# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- zf-CCHC_3 PF13917.6 CDJ36917.1 - 3.1e-05 23.9 0.7 7e-05 22.7 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle SR-25 PF10500.9 CDJ36917.1 - 3.5e-05 23.5 41.9 0.00091 18.9 29.5 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.23 CDJ36917.1 - 0.00024 21.0 1.1 0.00036 20.5 1.1 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF3446 PF11928.8 CDJ36917.1 - 0.0072 16.6 13.4 0.1 12.9 4.5 2.3 2 0 0 2 2 2 2 Early growth response N-terminal domain RR_TM4-6 PF06459.12 CDJ36917.1 - 1.1 9.0 11.2 1.9 8.2 11.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCDC106 PF15794.5 CDJ36917.1 - 1.4 8.5 25.0 0.75 9.5 18.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 TFIIF_alpha PF05793.12 CDJ36917.1 - 2.2 6.8 23.8 0.37 9.3 19.4 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4674 PF15719.5 CDJ36917.1 - 3 7.9 24.8 1.1 9.3 19.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) CDC45 PF02724.14 CDJ36917.1 - 3.5 5.8 20.6 4.6 5.4 20.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Smg8_Smg9 PF10220.9 CDJ36917.1 - 5.7 5.1 11.7 7.2 4.8 11.7 1.1 1 0 0 1 1 1 0 Smg8_Smg9 DUF966 PF06136.13 CDJ36918.1 - 3.2 7.4 34.7 5 6.8 34.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) NST1 PF13945.6 CDJ36918.1 - 7.4 6.6 45.5 3.5 7.7 23.2 2.7 1 1 2 3 3 3 0 Salt tolerance down-regulator Pex14_N PF04695.13 CDJ36919.1 - 2.7e-16 60.6 2.4 2.7e-16 60.6 2.4 11.7 6 3 4 10 10 10 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Mucin PF01456.17 CDJ36920.1 - 0.083 12.9 1.7 0.14 12.2 1.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Activator_LAG-3 PF11498.8 CDJ36920.1 - 0.13 11.2 6.4 0.18 10.7 6.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PsbQ PF05757.11 CDJ36920.1 - 0.48 10.1 6.8 3.3 7.4 2.2 2.3 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) SUIM_assoc PF16619.5 CDJ36920.1 - 1.8 8.7 7.1 4.7 7.4 7.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Profilin PF00235.19 CDJ36921.1 - 0.00043 20.5 0.0 0.0006 20.1 0.0 1.3 1 0 0 1 1 1 1 Profilin Na_H_antiport_3 PF07399.11 CDJ36921.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Putative Na+/H+ antiporter Ribosomal_S11 PF00411.19 CDJ36922.1 - 3.1e-47 159.5 1.4 3.1e-47 159.5 1.4 1.5 2 0 0 2 2 2 1 Ribosomal protein S11 DUF2423 PF10338.9 CDJ36923.1 - 4.2e-12 46.1 2.6 1.2e-11 44.6 2.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Ribosomal_60s PF00428.19 CDJ36923.1 - 0.77 10.4 10.3 3.4 8.3 9.7 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Gly_transf_sug PF04488.15 CDJ36924.1 - 4.1e-07 30.6 0.0 9.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF974 PF06159.13 CDJ36924.1 - 0.036 13.9 0.0 0.084 12.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF974) EphA2_TM PF14575.6 CDJ36924.1 - 7.1 7.6 5.7 6.3 7.8 0.6 3.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain MFS_1 PF07690.16 CDJ36925.1 - 0.0057 15.6 2.0 0.0057 15.6 2.0 3.3 3 0 0 3 3 3 2 Major Facilitator Superfamily MreB_Mbl PF06723.13 CDJ36927.1 - 0.093 11.5 0.1 1.8 7.3 0.0 2.0 1 1 1 2 2 2 0 MreB/Mbl protein DUF2163 PF09931.9 CDJ36928.1 - 0.0099 16.1 1.9 41 4.4 0.0 5.1 5 2 1 6 6 6 1 Uncharacterized conserved protein (DUF2163) HU-HIG PF18291.1 CDJ36928.1 - 0.043 13.9 4.0 7 6.8 0.0 3.4 5 0 0 5 5 5 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Lbh PF15317.6 CDJ36928.1 - 5 8.0 8.6 37 5.3 0.2 4.1 4 0 0 4 4 4 0 Cardiac transcription factor regulator, Developmental protein zf-U11-48K PF05253.12 CDJ36928.1 - 5.4 7.0 5.2 2.8e+02 1.6 0.0 4.4 4 0 0 4 4 4 0 U11-48K-like CHHC zinc finger TraC PF07820.12 CDJ36930.1 - 4.6e-05 23.7 0.4 18 5.8 0.0 4.1 4 0 0 4 4 4 3 TraC-like protein FERM_N PF09379.10 CDJ36930.1 - 0.00099 19.0 0.1 14 5.7 0.0 3.3 3 0 0 3 3 3 3 FERM N-terminal domain DUF1938 PF09153.10 CDJ36930.1 - 0.012 15.7 0.0 19 5.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1938) Mtd_N PF18454.1 CDJ36930.1 - 0.35 10.9 1.0 66 3.7 0.0 4.0 4 0 0 4 4 4 0 Major tropism determinant N-terminal domain Y_phosphatase2 PF03162.13 CDJ36930.1 - 1.2 8.7 3.4 2.8 7.5 0.2 2.6 2 1 1 3 3 3 0 Tyrosine phosphatase family PAM2 PF07145.15 CDJ36932.1 - 0.011 15.3 0.5 0.029 14.0 0.5 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region RNA_pol_3_Rpc31 PF11705.8 CDJ36933.1 - 1.8 8.8 14.6 4.5 7.5 0.7 2.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nucleoside_tran PF01733.18 CDJ36934.1 - 7.5e-19 68.2 9.6 6.1e-12 45.5 3.1 2.4 2 0 0 2 2 2 2 Nucleoside transporter TFIIA PF03153.13 CDJ36935.1 - 0.16 12.0 9.0 0.17 11.9 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ36935.1 - 1.5 7.0 5.8 1.6 6.9 5.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 CDJ36935.1 - 2.6 7.6 11.1 3.5 7.2 11.1 1.1 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 CDJ36935.1 - 7.6 5.1 9.9 8.3 5.0 9.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup VID27 PF08553.10 CDJ36936.1 - 3.6e-36 125.0 0.0 5.4e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain TFIIA PF03153.13 CDJ36936.1 - 0.001 19.1 15.4 0.0018 18.3 15.4 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ36936.1 - 0.0022 17.0 5.4 0.0022 17.0 5.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DUF4578 PF15147.6 CDJ36936.1 - 0.0089 16.9 5.0 0.03 15.2 5.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4578) Suf PF05843.14 CDJ36936.1 - 0.056 13.4 3.4 0.11 12.5 3.4 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FlaG PF03646.15 CDJ36936.1 - 0.31 11.2 7.8 0.8 9.9 7.8 1.7 1 0 0 1 1 1 0 FlaG protein PDE6_gamma PF04868.12 CDJ36936.1 - 0.32 11.2 1.9 0.9 9.8 1.9 1.7 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit Coilin_N PF15862.5 CDJ36936.1 - 9.8 6.0 14.5 0.64 9.8 8.6 2.1 2 0 0 2 2 2 0 Coilin N-terminus Peptidase_C13 PF01650.18 CDJ36937.1 - 7.1e-28 97.8 7.7 5.8e-21 75.2 0.0 3.0 3 0 0 3 3 3 2 Peptidase C13 family RskA PF10099.9 CDJ36937.1 - 0.0039 17.5 15.3 0.0039 17.5 15.3 5.8 4 2 1 5 5 5 2 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ36937.1 - 0.0052 15.6 2.1 0.0052 15.6 2.1 3.1 2 1 0 2 2 1 1 Presenilin DUF789 PF05623.12 CDJ36937.1 - 0.0084 15.8 1.6 0.0084 15.8 1.6 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF789) DUF2052 PF09747.9 CDJ36937.1 - 0.02 15.1 18.2 1.8 8.7 0.1 3.8 4 0 0 4 4 4 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 CDJ36937.1 - 0.023 14.4 9.0 3.2 7.4 3.4 3.3 3 0 0 3 3 3 0 FAM176 family CAF1 PF04857.20 CDJ36937.1 - 0.033 13.3 2.4 1.1 8.4 0.1 2.4 2 0 0 2 2 2 0 CAF1 family ribonuclease MecA PF05389.12 CDJ36937.1 - 0.039 13.6 7.4 0.15 11.6 1.2 3.3 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) V_ATPase_I PF01496.19 CDJ36937.1 - 0.6 8.0 15.4 0.17 9.7 4.2 3.0 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family DUF4450 PF14614.6 CDJ36937.1 - 0.64 9.5 6.7 1.7 8.2 6.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) DUF4834 PF16118.5 CDJ36937.1 - 0.91 10.5 31.0 6 7.9 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) DUF3807 PF12720.7 CDJ36937.1 - 1.6 9.0 30.8 0.33 11.2 9.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) Connexin PF00029.19 CDJ36937.1 - 1.7 8.4 11.2 1.1 9.0 3.5 3.0 3 0 0 3 3 3 0 Connexin DUF1980 PF09323.10 CDJ36937.1 - 2.2 8.2 13.9 7.5 6.4 4.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Scs3p PF10261.9 CDJ36937.1 - 2.9 7.3 5.2 16 4.9 0.1 2.5 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM Sarcoglycan_2 PF05510.13 CDJ36937.1 - 5.7 5.6 10.0 1.1 8.0 2.9 2.3 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon SpoIIP PF07454.11 CDJ36937.1 - 6.4 6.2 22.3 1.9 7.8 8.6 3.1 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) zf-RING_2 PF13639.6 CDJ36938.1 - 3.9e-08 33.5 18.4 3.9e-08 33.5 18.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ36938.1 - 2e-05 24.3 17.3 2e-05 24.3 17.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ36938.1 - 2.8e-05 23.8 9.9 2.8e-05 23.8 9.9 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 CDJ36938.1 - 4.4e-05 23.7 14.7 4.4e-05 23.7 14.7 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CDJ36938.1 - 0.0079 16.2 10.3 0.0079 16.2 10.3 3.2 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ36938.1 - 0.014 15.2 17.7 0.014 15.2 17.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ36938.1 - 2.6 8.2 10.6 0.92 9.6 6.8 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CDJ36938.1 - 7.8 6.6 26.5 0.31 11.0 17.3 2.5 2 0 0 2 2 2 0 zinc-RING finger domain Telomere_Sde2_2 PF13297.6 CDJ36939.1 - 0.051 13.2 1.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Telomere stability C-terminal TIM PF00121.18 CDJ36940.1 - 1.4e-66 224.3 0.0 1.8e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase DUF1800 PF08811.11 CDJ36940.1 - 0.031 13.3 0.2 0.052 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Lsr2 PF11774.8 CDJ36940.1 - 0.26 11.4 1.0 0.37 11.0 0.1 1.7 2 0 0 2 2 2 0 Lsr2 MT-A70 PF05063.14 CDJ36941.1 - 1.6e-57 194.1 0.4 1.6e-57 194.1 0.4 1.9 2 0 0 2 2 2 1 MT-A70 Cauli_DNA-bind PF03310.13 CDJ36941.1 - 0.18 11.9 2.7 0.25 11.4 0.1 2.5 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein DUF508 PF04370.12 CDJ36941.1 - 9.5 6.0 10.6 0.8 9.4 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF508) LRR_4 PF12799.7 CDJ36942.1 - 1.7e-15 56.9 9.2 0.00051 20.4 1.3 4.8 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ36942.1 - 9.4e-10 38.1 10.0 0.00013 21.6 0.1 4.6 4 0 0 4 4 4 3 Leucine rich repeat eIF-3_zeta PF05091.12 CDJ36942.1 - 0.0023 17.0 11.0 0.0023 17.0 11.0 4.2 3 1 1 4 4 4 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF5308 PF17233.2 CDJ36942.1 - 0.017 15.4 4.0 0.017 15.4 4.0 5.8 3 2 0 4 4 4 0 Family of unknown function (DUF5308) LRR_1 PF00560.33 CDJ36942.1 - 0.65 10.8 14.5 2.6 8.9 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat DHHC PF01529.20 CDJ36943.1 - 9.6e-27 93.7 8.0 9.6e-27 93.7 8.0 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 CDJ36943.1 - 2.8e-16 59.9 0.4 1.3e-08 35.3 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ36943.1 - 3e-12 46.8 3.3 1.1e-05 25.8 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ36943.1 - 2.2e-11 42.9 3.1 3.6e-06 26.9 0.0 5.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CDJ36943.1 - 4.1e-11 42.8 2.0 4.8e-07 29.9 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 CDJ36943.1 - 1.6e-08 34.7 0.5 8.4e-06 26.0 0.1 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) MpPF26 PF07666.11 CDJ36943.1 - 2.6 8.2 10.2 0.071 13.2 3.3 1.8 2 0 0 2 2 2 0 M penetrans paralogue family 26 Ribosomal_L19 PF01245.20 CDJ36944.1 - 6.6e-13 48.6 0.0 1.7e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L19 Alpha-amylase PF00128.24 CDJ36946.1 - 9e-17 61.6 0.0 7.9e-10 38.8 0.0 2.4 1 1 0 2 2 2 2 Alpha amylase, catalytic domain Alpha-amyl_C2 PF07821.12 CDJ36946.1 - 3.8e-13 49.5 0.5 8.8e-13 48.3 0.5 1.7 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain fn3 PF00041.21 CDJ36946.1 - 0.0005 20.4 0.0 0.0005 20.4 0.0 3.1 4 1 0 4 4 4 1 Fibronectin type III domain Macoilin PF09726.9 CDJ36946.1 - 0.0034 16.0 9.6 0.0058 15.3 9.6 1.4 1 0 0 1 1 1 1 Macoilin family SPX PF03105.19 CDJ36946.1 - 0.61 9.9 19.9 0.039 13.9 13.7 1.8 2 0 0 2 2 2 0 SPX domain Apt1 PF10351.9 CDJ36946.1 - 1.2 7.9 16.3 0.055 12.3 10.9 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain Calpain_III PF01067.22 CDJ36947.1 - 0.093 13.0 0.5 13 6.1 0.0 3.9 5 1 0 5 5 5 0 Calpain large subunit, domain III Peptidase_C2 PF00648.21 CDJ36948.1 - 1.2e-05 24.5 0.0 0.0012 17.9 0.0 2.9 2 1 0 2 2 2 1 Calpain family cysteine protease PhyH PF05721.13 CDJ36950.1 - 0.00076 19.8 0.6 0.19 12.0 0.0 2.9 2 1 1 3 3 3 2 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.16 CDJ36950.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family PBP1_TM PF14812.6 CDJ36951.1 - 0.011 16.1 0.5 0.013 15.9 0.5 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PTPRCAP PF15713.5 CDJ36951.1 - 0.026 14.8 5.0 0.029 14.6 5.0 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated FAM176 PF14851.6 CDJ36951.1 - 0.026 14.2 2.4 0.03 14.0 2.4 1.1 1 0 0 1 1 1 0 FAM176 family SLAIN PF15301.6 CDJ36951.1 - 0.038 13.3 3.0 0.044 13.0 3.0 1.0 1 0 0 1 1 1 0 SLAIN motif-containing family DR2241 PF18069.1 CDJ36951.1 - 0.042 13.7 0.9 0.051 13.4 0.9 1.1 1 0 0 1 1 1 0 DR2241 stabilising domain MPP6 PF10175.9 CDJ36951.1 - 0.046 14.2 4.0 0.057 13.9 4.0 1.1 1 0 0 1 1 1 0 M-phase phosphoprotein 6 Pox_Ag35 PF03286.14 CDJ36951.1 - 0.11 12.3 2.0 0.13 12.1 2.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PAC1 PF16094.5 CDJ36951.1 - 5 6.2 6.0 5.8 6.0 6.0 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Cullin PF00888.22 CDJ36952.1 - 4.8e-139 464.8 8.5 6.7e-139 464.3 8.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDJ36952.1 - 2e-22 79.0 0.2 1e-21 76.7 0.2 2.4 1 0 0 1 1 1 1 Cullin protein neddylation domain DAP PF15228.6 CDJ36952.1 - 0.0059 17.8 2.5 0.016 16.4 0.1 2.6 2 0 0 2 2 2 1 Death-associated protein DUF445 PF04286.12 CDJ36952.1 - 0.24 11.1 7.3 0.32 10.8 1.0 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF445) PKD_channel PF08016.12 CDJ36953.1 - 4.9e-10 38.7 13.2 1.3e-09 37.2 13.2 1.7 1 0 0 1 1 1 1 Polycystin cation channel Pox_A14 PF05767.12 CDJ36954.1 - 0.27 11.4 5.0 4.2 7.6 0.1 3.6 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Ost4 PF10215.9 CDJ36954.1 - 0.88 9.5 4.8 1.4 8.8 1.6 2.7 2 0 0 2 2 2 0 Oligosaccaryltransferase PKD_channel PF08016.12 CDJ36956.1 - 3e-10 39.3 11.5 3e-10 39.3 11.5 2.7 3 0 0 3 3 3 1 Polycystin cation channel Ion_trans PF00520.31 CDJ36956.1 - 0.36 10.0 26.3 0.049 12.9 18.4 2.9 2 2 0 2 2 2 0 Ion transport protein Kinesin PF00225.23 CDJ36957.1 - 2.9e-85 286.1 0.2 7.3e-43 146.8 0.3 2.5 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ36957.1 - 9.4e-21 74.3 0.1 3.5e-20 72.5 0.1 2.0 1 1 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 CDJ36957.1 - 0.00053 20.4 0.0 0.005 17.3 0.0 2.6 2 0 0 2 2 2 1 Kinesin protein 1B Kinesin_assoc PF16183.5 CDJ36957.1 - 0.032 14.4 0.3 0.032 14.4 0.3 3.8 3 2 2 5 5 5 0 Kinesin-associated AAA_22 PF13401.6 CDJ36957.1 - 2.3 8.5 4.6 16 5.7 0.1 3.4 3 0 0 3 3 3 0 AAA domain ATG16 PF08614.11 CDJ36957.1 - 2.8 8.1 35.8 1.4 9.1 17.5 3.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DNA_pol_B_exo1 PF03104.19 CDJ36959.1 - 0.11 11.6 0.0 0.5 9.4 0.0 1.8 1 1 0 1 1 1 0 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CDJ36960.1 - 2.8e-32 112.1 0.0 4.7e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B PF00136.21 CDJ36961.1 - 3.4e-36 124.9 0.0 4.9e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 CDJ36961.1 - 3.1e-07 30.7 7.4 8e-07 29.4 3.8 2.7 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta AMP-binding PF00501.28 CDJ36963.1 - 1.9e-21 76.2 0.0 1.4e-19 70.0 0.0 3.0 2 1 0 2 2 2 1 AMP-binding enzyme zf-C2H2_2 PF12756.7 CDJ36964.1 - 4e-17 62.4 1.5 4e-17 62.4 1.5 3.0 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CDJ36964.1 - 0.99 9.8 4.4 6.9 7.1 0.3 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Mito_carr PF00153.27 CDJ36965.1 - 1.7e-56 188.1 10.6 3.1e-23 81.5 0.0 4.6 5 0 0 5 5 5 4 Mitochondrial carrier protein Histone PF00125.24 CDJ36967.1 - 2.9e-17 63.2 0.0 4e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CDJ36967.1 - 6.5e-11 41.8 0.1 1.3e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CDJ36967.1 - 8.3e-05 22.8 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NAGLU PF05089.12 CDJ36970.1 - 0.045 12.7 0.1 0.078 11.9 0.1 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain tRNA_SAD PF07973.14 CDJ36970.1 - 0.087 12.9 0.3 0.29 11.2 0.3 1.9 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain Sec16_C PF12931.7 CDJ36971.1 - 0.01 15.5 0.7 0.019 14.7 0.5 1.5 1 1 0 1 1 1 0 Sec23-binding domain of Sec16 RRN9 PF10680.9 CDJ36971.1 - 0.2 12.0 0.9 0.32 11.3 0.2 1.8 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor TPR_2 PF07719.17 CDJ36971.1 - 8 6.9 6.7 35 4.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 CDJ36972.1 - 0.031 13.3 0.3 0.046 12.8 0.3 1.2 1 0 0 1 1 1 0 Coatomer WD associated region TPH PF13868.6 CDJ36973.1 - 7.1e-10 37.9 143.6 7.1e-10 37.9 143.6 2.3 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain DUF3384 PF11864.8 CDJ36974.1 - 0.0027 16.7 5.0 0.37 9.6 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3384) RIX1 PF08167.12 CDJ36974.1 - 0.0036 17.1 3.4 0.005 16.6 1.0 2.4 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 CDJ36974.1 - 1.2 8.7 5.3 5.1 6.6 1.0 3.2 2 1 1 3 3 3 0 CLASP N terminal Cnd1 PF12717.7 CDJ36975.1 - 0.00023 21.2 2.6 0.066 13.2 0.1 4.1 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Hexokinase_2 PF03727.16 CDJ36975.1 - 0.018 14.5 4.8 0.037 13.4 0.6 2.7 3 0 0 3 3 3 0 Hexokinase HEAT PF02985.22 CDJ36975.1 - 0.018 15.2 13.1 0.037 14.3 0.2 5.3 5 0 0 5 5 5 0 HEAT repeat WD40 PF00400.32 CDJ36976.1 - 6.9e-07 29.9 1.1 0.047 14.6 0.0 4.3 3 1 1 4 4 4 2 WD domain, G-beta repeat AAA_33 PF13671.6 CDJ36977.1 - 0.015 15.4 0.5 0.06 13.5 0.2 2.3 2 0 0 2 2 2 0 AAA domain FAP206 PF12018.8 CDJ36977.1 - 0.038 13.5 0.0 0.13 11.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function FAP206 PF12018.8 CDJ36978.1 - 1.6e-11 44.3 0.0 1.7e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function ADK PF00406.22 CDJ36978.1 - 0.0043 17.2 0.0 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 Adenylate kinase DUF2201_N PF13203.6 CDJ36978.1 - 0.14 11.7 3.7 0.62 9.6 3.7 2.1 1 0 0 1 1 1 0 Putative metallopeptidase domain NARP1 PF12569.8 CDJ36978.1 - 7.7 5.3 8.6 4.2 6.2 6.0 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 AMA-1 PF02430.15 CDJ36979.1 - 3.2e-65 220.9 0.2 8.4e-65 219.5 0.2 1.6 1 1 0 1 1 1 1 Apical membrane antigen 1 FAM176 PF14851.6 CDJ36979.1 - 0.011 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 FAM176 family Chordopox_A13L PF05961.11 CDJ36979.1 - 0.1 12.9 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF4710 PF15828.5 CDJ36979.1 - 1.5 9.0 6.1 1.5e+02 2.5 7.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) WD40 PF00400.32 CDJ36980.1 - 5.7e-06 27.0 10.2 0.0017 19.1 0.0 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF4205 PF13898.6 CDJ36981.1 - 5e-50 170.4 0.1 1.2e-48 165.8 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4205) DUF2722 PF10846.8 CDJ36981.1 - 2 7.2 22.3 0.03 13.3 6.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Sld5 PF05916.11 CDJ36982.1 - 2e-07 31.4 0.1 3.2e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein Ribosomal_L24e PF01246.20 CDJ36983.1 - 4.7e-32 110.0 5.5 9.5e-32 109.0 5.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.14 CDJ36983.1 - 0.019 14.9 2.9 0.019 14.9 2.9 1.9 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif TFIIA PF03153.13 CDJ36983.1 - 0.089 12.8 16.3 0.11 12.5 16.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit REC114-like PF15165.6 CDJ36983.1 - 0.32 10.7 13.4 0.51 10.1 13.4 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like BIRC6 PF12356.8 CDJ36983.1 - 0.77 9.2 8.8 1.2 8.6 8.8 1.2 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 STAC2_u1 PF16664.5 CDJ36983.1 - 1.8 9.0 12.3 1.6 9.2 11.1 1.5 1 1 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF4820 PF16091.5 CDJ36983.1 - 3.6 6.9 14.8 3.6 6.9 13.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) MMR_HSR1 PF01926.23 CDJ36984.1 - 2.1e-13 50.3 0.0 5.5e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 CDJ36984.1 - 3.2e-10 39.8 14.5 9.5e-06 25.3 3.3 3.7 2 1 1 3 3 3 2 GTP1/OBG FeoB_N PF02421.18 CDJ36984.1 - 5.1e-05 22.9 0.0 0.0017 17.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDJ36984.1 - 0.0023 17.5 0.1 0.0045 16.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 CDJ36984.1 - 0.0035 17.0 0.1 0.075 12.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 CDJ36984.1 - 0.0044 16.5 0.2 0.56 9.6 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 CDJ36984.1 - 0.12 12.4 2.4 8.1 6.5 0.0 3.2 1 1 2 3 3 3 0 Dynamin family Cob_adeno_trans PF01923.18 CDJ36984.1 - 0.14 12.2 4.0 0.6 10.2 0.0 3.0 3 0 0 3 3 3 0 Cobalamin adenosyltransferase ATP_bind_1 PF03029.17 CDJ36984.1 - 0.98 9.2 3.0 3.5 7.3 2.1 2.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 CDJ36984.1 - 2.2 8.5 4.4 4.6 7.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain TFIIA PF03153.13 CDJ36984.1 - 9.3 6.1 40.3 6.1 6.7 30.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S15 PF00312.22 CDJ36985.1 - 0.00066 19.8 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 SUIM_assoc PF16619.5 CDJ36985.1 - 0.018 15.1 4.8 0.018 15.1 4.8 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Med24_N PF11277.8 CDJ36985.1 - 0.14 10.2 1.1 0.17 9.9 1.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Spt20 PF12090.8 CDJ36985.1 - 0.17 11.5 14.3 0.32 10.6 10.5 2.1 2 0 0 2 2 2 0 Spt20 family Presenilin PF01080.17 CDJ36985.1 - 0.81 8.4 4.7 0.93 8.2 4.7 1.2 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 CDJ36985.1 - 1.2 7.4 7.3 1.4 7.2 7.3 1.1 1 0 0 1 1 1 0 Menin Hid1 PF12722.7 CDJ36985.1 - 2.1 6.4 4.2 1.9 6.5 4.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_S15 PF00312.22 CDJ36986.1 - 2.3e-10 40.5 2.1 2.3e-10 40.5 2.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_L6e PF01159.19 CDJ36986.1 - 0.058 13.9 2.8 0.1 13.2 2.8 1.3 1 0 0 1 1 1 0 Ribosomal protein L6e Ribosomal_L4 PF00573.22 CDJ36987.1 - 3.7e-36 124.6 0.0 6.2e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family ELO PF01151.18 CDJ36988.1 - 6.2e-63 212.6 24.4 7.6e-63 212.3 24.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Sec7 PF01369.20 CDJ36989.1 - 3.3e-58 196.4 0.0 5.5e-58 195.7 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CDJ36989.1 - 2.5e-11 43.8 0.0 8.4e-11 42.0 0.0 2.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CDJ36989.1 - 5.7e-09 35.7 0.0 2.3e-08 33.7 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) SUIM_assoc PF16619.5 CDJ36989.1 - 0.22 11.6 0.0 0.22 11.6 0.0 17.5 13 3 2 15 15 15 0 Unstructured region C-term to UIM in Ataxin3 Mito_carr PF00153.27 CDJ36989.1 - 0.61 10.0 3.9 0.71 9.8 0.1 3.4 2 0 0 2 2 2 0 Mitochondrial carrier protein UCR_UQCRX_QCR9 PF05365.12 CDJ36990.1 - 8.4e-15 54.5 5.2 1.2e-14 54.0 5.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF2593 PF10767.9 CDJ36990.1 - 0.033 14.3 0.3 0.035 14.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) Ribosomal_L37 PF08561.10 CDJ36990.1 - 0.17 12.4 0.3 0.2 12.2 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 SNF2_N PF00176.23 CDJ36991.1 - 3.4e-51 174.0 0.0 8.7e-51 172.7 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.29 CDJ36991.1 - 1.7e-20 72.7 81.9 2e-10 40.4 6.5 7.1 7 1 0 7 7 7 4 PHD-finger Helicase_C PF00271.31 CDJ36991.1 - 1.2e-12 48.2 0.3 4.6e-12 46.3 0.0 2.2 2 0 0 2 2 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ36991.1 - 3.6e-08 33.6 0.0 9.3e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD_4 PF16866.5 CDJ36991.1 - 0.00053 20.0 58.7 0.0058 16.7 6.2 6.7 5 0 0 5 5 5 4 PHD-finger PHD_2 PF13831.6 CDJ36991.1 - 0.001 18.5 1.7 0.001 18.5 1.7 6.6 7 0 0 7 7 6 1 PHD-finger zf-PHD-like PF15446.6 CDJ36991.1 - 0.0048 16.5 1.9 0.0048 16.5 1.9 8.0 7 2 2 9 9 9 4 PHD/FYVE-zinc-finger like domain AAA_14 PF13173.6 CDJ36991.1 - 0.0054 16.8 0.0 0.017 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Prok-RING_1 PF14446.6 CDJ36991.1 - 0.0064 16.4 2.3 0.0064 16.4 2.3 6.7 7 0 0 7 7 6 2 Prokaryotic RING finger family 1 C1_1 PF00130.22 CDJ36991.1 - 0.0077 16.1 1.6 0.0077 16.1 1.6 7.5 6 1 1 7 7 6 4 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4710 PF15828.5 CDJ36991.1 - 0.48 10.6 6.6 0.045 13.9 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) ENOD40 PF08247.11 CDJ36992.1 - 0.18 11.8 0.4 0.38 10.8 0.4 1.5 1 0 0 1 1 1 0 ENOD40 protein Nop53 PF07767.11 CDJ36993.1 - 2.1 7.7 18.7 2.4 7.4 18.7 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF5401 PF17380.2 CDJ36993.1 - 5.9 4.8 23.8 6.3 4.7 23.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) SET PF00856.28 CDJ36994.1 - 1.8e-10 41.5 0.0 1.8e-10 41.5 0.0 3.6 3 2 0 3 3 3 1 SET domain HypA PF01155.19 CDJ36994.1 - 0.095 12.7 0.5 0.34 10.9 0.5 1.9 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Arm PF00514.23 CDJ36995.1 - 9.4e-08 31.9 9.3 0.061 13.4 0.0 6.2 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 CDJ36995.1 - 6.7e-06 26.2 0.1 5.4e-05 23.3 0.0 2.3 3 0 0 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.6 CDJ36995.1 - 0.00012 22.4 0.1 0.029 14.7 0.0 3.7 2 1 2 4 4 4 1 HEAT repeats HEAT PF02985.22 CDJ36995.1 - 0.053 13.8 4.2 43 4.8 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat Calpain_inhib PF00748.19 CDJ36995.1 - 0.19 12.3 1.4 0.36 11.3 1.4 1.4 1 0 0 1 1 1 0 Calpain inhibitor Tim17 PF02466.19 CDJ36997.1 - 7.6e-23 81.0 6.5 1.1e-22 80.5 6.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4199 PF13858.6 CDJ36997.1 - 0.11 12.9 0.0 0.16 12.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) Phage_holin_3_3 PF16083.5 CDJ36997.1 - 0.12 12.5 6.1 4.1 7.6 0.5 2.8 3 1 0 3 3 3 0 LydA holin phage, holin superfamily III Spectrin_like PF18373.1 CDJ36999.1 - 0.0052 16.8 0.1 0.048 13.7 0.0 2.3 2 0 0 2 2 2 1 Spectrin like domain UvrD-helicase PF00580.21 CDJ37000.1 - 2e-46 158.9 1.1 1.8e-42 146.0 0.0 2.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CDJ37000.1 - 2e-29 103.1 0.0 1.1e-22 80.9 0.0 4.6 3 1 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CDJ37000.1 - 5.3e-20 72.2 0.0 1.8e-19 70.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CDJ37000.1 - 5e-10 39.1 1.5 0.00042 20.1 0.0 3.4 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain Evr1_Alr PF04777.13 CDJ37001.1 - 1.1e-20 73.9 0.0 1.4e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 Erv1 / Alr family DHO_dh PF01180.21 CDJ37002.1 - 7.2e-104 347.1 0.0 8.4e-104 346.9 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CDJ37002.1 - 0.001 18.2 0.6 0.0023 17.0 0.4 1.8 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 CDJ37002.1 - 0.038 13.4 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase IMPDH PF00478.25 CDJ37002.1 - 0.13 11.2 0.2 0.22 10.5 0.2 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Fusion_gly PF00523.18 CDJ37004.1 - 0.018 13.3 0.6 0.032 12.5 0.6 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 PRKCSH PF07915.13 CDJ37005.1 - 1.1e-12 48.8 0.0 6.2e-06 27.1 0.0 2.9 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein YccV-like PF08755.11 CDJ37005.1 - 9.3e-11 42.1 0.4 4.3e-10 40.0 0.4 2.0 1 1 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like PRKCSH_1 PF13015.6 CDJ37005.1 - 8.8e-05 22.2 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein UCH PF00443.29 CDJ37007.1 - 1.4e-37 129.6 0.0 2e-36 125.8 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ37007.1 - 2e-05 24.4 0.0 2e-05 24.4 0.0 3.9 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Fer4_2 PF12797.7 CDJ37007.1 - 0.25 11.5 1.6 0.94 9.7 1.6 2.1 1 0 0 1 1 1 0 4Fe-4S binding domain ABC_tran PF00005.27 CDJ37008.1 - 1.5e-44 151.8 0.6 4.7e-22 79.0 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 CDJ37008.1 - 4.1e-19 69.5 3.3 5.7e-06 26.4 0.1 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 CDJ37008.1 - 1.8e-18 66.3 2.6 1.8e-18 66.3 2.6 3.1 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 CDJ37008.1 - 2.2e-09 37.1 4.1 5.8e-06 25.9 3.0 4.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ37008.1 - 3.3e-07 29.9 0.3 0.016 15.0 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_15 PF13175.6 CDJ37008.1 - 1.8e-06 28.0 3.9 0.097 12.4 0.6 4.0 3 1 1 4 4 4 2 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ37008.1 - 3.1e-06 27.2 0.0 0.048 13.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDJ37008.1 - 5.8e-06 26.4 0.0 0.18 11.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 CDJ37008.1 - 1.5e-05 25.2 0.9 0.047 13.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 CDJ37008.1 - 3.2e-05 24.5 0.2 0.05 14.2 0.0 4.0 4 0 0 4 4 4 1 AAA domain Dynamin_N PF00350.23 CDJ37008.1 - 3.5e-05 23.9 0.1 0.24 11.4 0.0 3.0 3 0 0 3 3 3 2 Dynamin family AAA_28 PF13521.6 CDJ37008.1 - 3.6e-05 24.1 0.3 0.061 13.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CDJ37008.1 - 0.0004 20.7 7.4 0.094 13.0 0.2 4.2 4 1 0 4 4 3 2 AAA domain NACHT PF05729.12 CDJ37008.1 - 0.00066 19.6 0.6 1.3 8.9 0.0 3.3 3 0 0 3 3 3 2 NACHT domain AAA_24 PF13479.6 CDJ37008.1 - 0.0032 17.2 0.0 1.5 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CDJ37008.1 - 0.011 15.7 0.2 11 6.0 0.0 3.3 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.22 CDJ37008.1 - 0.014 15.7 0.0 4.6 7.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase MeaB PF03308.16 CDJ37008.1 - 0.017 14.1 0.0 2.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 CDJ37008.1 - 0.025 14.0 0.1 0.79 9.2 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family Septin PF00735.18 CDJ37008.1 - 0.04 13.2 0.2 13 5.0 0.0 2.9 2 1 1 3 3 3 0 Septin AAA_16 PF13191.6 CDJ37008.1 - 0.045 14.1 3.8 6.5 7.1 0.0 3.5 3 1 0 3 3 3 0 AAA ATPase domain DUF3584 PF12128.8 CDJ37008.1 - 0.048 11.2 0.0 0.048 11.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) FtsK_SpoIIIE PF01580.18 CDJ37008.1 - 0.055 12.8 2.3 1.6 8.0 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF87 PF01935.17 CDJ37008.1 - 0.059 13.4 2.5 1.8 8.6 0.0 3.2 4 0 0 4 4 4 0 Helicase HerA, central domain NTPase_1 PF03266.15 CDJ37008.1 - 0.073 13.0 0.0 18 5.2 0.0 3.1 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.22 CDJ37008.1 - 0.074 12.2 0.0 6.9 5.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 CDJ37008.1 - 0.14 11.9 0.7 68 3.1 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 CDJ37008.1 - 0.14 12.6 0.3 0.14 12.6 0.3 4.9 3 3 3 6 6 5 0 AAA domain S4 PF01479.25 CDJ37009.1 - 7.5e-06 25.6 0.1 2.5e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 S4 domain PseudoU_synth_2 PF00849.22 CDJ37009.1 - 5.5e-05 23.3 0.0 9.6e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 RNA pseudouridylate synthase Steroid_dh PF02544.16 CDJ37010.1 - 1.6e-35 122.3 4.7 2.7e-35 121.6 4.7 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 CDJ37010.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family YukD PF08817.10 CDJ37010.1 - 0.019 15.7 0.0 0.033 14.9 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DUF2340 PF10209.9 CDJ37010.1 - 0.11 12.9 0.2 0.25 11.8 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2340) zf-met2 PF12907.7 CDJ37011.1 - 6.5e-16 58.2 6.7 8.8e-16 57.8 6.7 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 CDJ37011.1 - 2.5e-08 34.7 5.9 3.8e-08 34.1 5.9 1.3 1 0 0 1 1 1 1 4F5 protein family zf-C2H2_12 PF18658.1 CDJ37011.1 - 0.0099 15.4 0.9 0.014 15.0 0.9 1.2 1 0 0 1 1 1 1 Zinc-finger C2H2-type Gram_pos_anchor PF00746.21 CDJ37012.1 - 0.038 13.9 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Podoplanin PF05808.11 CDJ37012.1 - 0.085 13.0 2.8 0.16 12.1 0.7 2.1 2 0 0 2 2 2 0 Podoplanin LapA_dom PF06305.11 CDJ37012.1 - 0.14 12.0 1.2 2.6 7.9 0.2 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Patched PF02460.18 CDJ37013.1 - 2.4e-88 297.2 0.0 1.3e-87 294.8 0.0 1.8 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ37013.1 - 3.2e-26 92.0 23.5 4.1e-25 88.4 1.3 2.4 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 CDJ37013.1 - 0.58 7.7 27.3 0.16 9.6 22.4 2.0 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family MtN3_slv PF03083.16 CDJ37014.1 - 2e-05 24.6 1.8 2e-05 24.6 1.8 1.8 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange FRQ PF09421.10 CDJ37014.1 - 8.3 4.3 17.7 0.11 10.6 9.5 1.7 2 0 0 2 2 2 0 Frequency clock protein Miga PF10265.9 CDJ37015.1 - 0.25 10.3 8.6 0.37 9.7 8.6 1.4 1 0 0 1 1 1 0 Mitoguardin Apt1 PF10351.9 CDJ37015.1 - 2.6 6.8 6.9 3.7 6.3 6.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain WD40 PF00400.32 CDJ37016.1 - 3.8e-26 90.8 1.2 1.2e-05 25.9 0.1 10.2 11 0 0 11 11 11 5 WD domain, G-beta repeat Utp13 PF08625.11 CDJ37016.1 - 1.5e-09 37.9 0.7 1.5e-09 37.9 0.7 2.8 3 0 0 3 3 3 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 CDJ37016.1 - 5.6e-07 29.8 0.2 0.73 10.2 0.0 5.9 5 1 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain TMEM51 PF15345.6 CDJ37016.1 - 7e-05 22.8 1.1 7e-05 22.8 1.1 6.1 7 1 0 7 7 7 1 Transmembrane protein 51 Ge1_WD40 PF16529.5 CDJ37016.1 - 0.0019 17.2 0.1 0.16 10.9 0.0 3.2 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4471 PF14740.6 CDJ37016.1 - 1.6 7.9 10.3 1.5 7.9 7.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) BAR_2 PF10455.9 CDJ37017.1 - 0.048 12.8 0.1 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking RskA PF10099.9 CDJ37017.1 - 1.2 9.4 5.6 4.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ37017.1 - 2 8.6 8.8 0.096 12.8 1.8 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PDEase_I PF00233.19 CDJ37018.1 - 4e-32 111.8 0.0 4e-32 111.8 0.0 4.8 4 1 1 5 5 5 1 3'5'-cyclic nucleotide phosphodiesterase Dsh_C PF12316.8 CDJ37018.1 - 0.0029 18.1 5.0 0.0029 18.1 5.0 5.3 3 1 1 4 4 4 1 Segment polarity protein dishevelled (Dsh) C terminal 14-3-3 PF00244.20 CDJ37019.1 - 4.6e-24 85.2 12.3 1.7e-20 73.5 1.8 3.9 3 1 0 3 3 3 2 14-3-3 protein DUF1690 PF07956.11 CDJ37019.1 - 2.3 8.6 17.6 2.2 8.7 4.3 3.6 3 1 0 3 3 3 0 Protein of Unknown function (DUF1690) SecY PF00344.20 CDJ37020.1 - 7.2e-70 235.6 11.6 1e-69 235.2 11.6 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CDJ37020.1 - 4.5e-16 58.4 1.8 5.5e-16 58.1 0.1 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p Spt20 PF12090.8 CDJ37020.1 - 0.13 11.9 21.0 0.055 13.1 5.6 2.2 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ37020.1 - 3.2 6.6 16.2 2.3 7.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RseC_MucC PF04246.12 CDJ37020.1 - 3.8 7.5 5.2 0.79 9.7 0.1 2.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC SUIM_assoc PF16619.5 CDJ37020.1 - 6 7.0 25.4 6.6 6.9 5.4 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 GT87 PF09594.10 CDJ37021.1 - 0.25 11.0 9.1 1.2 8.8 0.1 2.0 2 0 0 2 2 2 0 Glycosyltransferase family 87 Chorion_2 PF03964.15 CDJ37021.1 - 0.49 11.3 15.1 0.56 11.1 4.3 2.3 2 0 0 2 2 2 0 Chorion family 2 DUF4148 PF13663.6 CDJ37021.1 - 0.53 10.5 16.9 0.22 11.8 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Roughex PF06020.11 CDJ37021.1 - 1.2 8.2 4.6 1.5 7.8 4.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein THOC2_N PF16134.5 CDJ37021.1 - 1.6 7.3 3.5 2.1 6.9 3.5 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus IHABP4_N PF16174.5 CDJ37021.1 - 6.2 7.4 13.0 0.42 11.2 4.3 2.1 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal GramPos_pilinD1 PF16555.5 CDJ37021.1 - 7.2 6.8 6.1 13 5.9 6.1 1.6 1 1 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain DUF2057 PF09829.9 CDJ37021.1 - 8.1 6.6 11.8 3.5 7.7 4.8 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) RRM_1 PF00076.22 CDJ37022.1 - 6.3e-31 106.0 0.0 2.6e-19 68.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CDJ37022.1 - 6.5e-05 22.9 0.0 0.11 12.6 0.0 2.4 2 1 0 2 2 2 2 Limkain b1 RRM_3 PF08777.11 CDJ37022.1 - 0.00064 19.7 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif ATP-grasp_2 PF08442.10 CDJ37022.1 - 0.6 9.6 0.0 1.5 8.3 0.0 2.5 3 0 0 3 3 3 0 ATP-grasp domain WD40 PF00400.32 CDJ37023.1 - 5.1e-12 46.1 0.6 0.0009 20.0 0.0 4.8 4 1 0 4 4 4 2 WD domain, G-beta repeat Guanylate_cyc PF00211.20 CDJ37025.1 - 3.4e-19 69.2 0.1 6.6e-12 45.4 0.1 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF572 PF04502.13 CDJ37027.1 - 3.1e-63 214.4 0.1 6.8e-63 213.3 0.1 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF572) Ribosomal_L11_N PF03946.14 CDJ37028.1 - 6.2e-22 77.2 0.1 1.1e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CDJ37028.1 - 2.1e-11 44.1 0.3 2.6e-06 27.8 0.0 2.4 1 1 1 2 2 2 2 Ribosomal protein L11, RNA binding domain DUF1180 PF06679.12 CDJ37029.1 - 0.86 10.0 4.0 4.2 7.8 4.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Biotin_lipoyl PF00364.22 CDJ37030.1 - 7.9e-12 44.8 1.2 1.6e-11 43.9 1.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme S36_mt PF10937.8 CDJ37030.1 - 0.0005 21.6 2.1 0.0005 21.6 2.1 1.9 2 1 0 2 2 2 1 Ribosomal protein S36, mitochondrial HlyD_D23 PF16576.5 CDJ37030.1 - 0.0027 17.0 0.9 0.0052 16.0 0.7 1.6 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 CDJ37030.1 - 0.0043 16.9 0.1 0.3 10.9 0.1 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like Spt20 PF12090.8 CDJ37030.1 - 0.0094 15.6 4.7 0.013 15.1 4.7 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ37030.1 - 0.025 14.6 3.6 0.032 14.2 3.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HlyD_3 PF13437.6 CDJ37030.1 - 0.049 14.3 0.4 11 6.7 0.1 2.5 1 1 1 2 2 2 0 HlyD family secretion protein MSP1_C PF07462.11 CDJ37030.1 - 0.57 8.8 1.7 0.93 8.1 1.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Roughex PF06020.11 CDJ37030.1 - 2.7 7.0 6.9 2.5 7.1 5.0 1.7 2 0 0 2 2 2 0 Drosophila roughex protein IMP2_N PF18590.1 CDJ37031.1 - 3.5e-26 91.6 0.1 6.1e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 CDJ37031.1 - 0.00033 20.5 0.5 0.0006 19.6 0.5 1.4 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) C-terminal domain DUF4623 PF15416.6 CDJ37031.1 - 0.12 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) DUF3987 PF13148.6 CDJ37031.1 - 0.37 9.7 4.6 0.56 9.2 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) REPA_OB_2 PF16900.5 CDJ37032.1 - 5.1e-19 68.0 0.0 1.8e-17 63.0 0.0 2.4 2 0 0 2 2 2 1 Replication protein A OB domain Rep_fac-A_C PF08646.10 CDJ37032.1 - 1.2e-07 31.6 0.1 2.1e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Replication factor-A C terminal domain Zn-ribbon_8 PF09723.10 CDJ37032.1 - 0.39 10.9 1.9 4.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 CDJ37032.1 - 0.6 10.2 3.7 1.4 9.0 3.7 1.7 1 1 0 1 1 1 0 Double zinc ribbon eIF-3c_N PF05470.12 CDJ37033.1 - 8.7e-134 447.0 20.3 2.6e-100 336.5 3.3 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CDJ37033.1 - 5.8e-12 46.0 0.5 2.8e-11 43.9 0.1 2.5 2 0 0 2 2 2 1 PCI domain Hid1 PF12722.7 CDJ37033.1 - 4.3 5.3 16.3 8.2 4.4 16.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SNF2_N PF00176.23 CDJ37034.1 - 4.8e-57 193.3 0.0 4.8e-57 193.3 0.0 3.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ37034.1 - 1.3e-18 67.3 0.1 7.8e-18 64.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ37034.1 - 3.5e-09 36.9 0.0 9.8e-08 32.2 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CDJ37034.1 - 3.6e-07 29.7 0.0 1.4e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Adaptin_N PF01602.20 CDJ37036.1 - 5.4e-96 322.2 1.4 5.7e-95 318.9 1.4 1.9 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CDJ37036.1 - 3.4e-16 59.5 0.0 7.5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CDJ37036.1 - 6.2e-06 26.3 1.2 0.14 12.1 0.0 3.5 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ37036.1 - 9.1e-06 26.0 14.8 0.015 15.7 0.5 5.2 3 3 0 3 3 3 2 HEAT repeats HEAT PF02985.22 CDJ37036.1 - 0.0059 16.8 4.1 0.25 11.7 0.3 5.0 4 1 1 5 5 5 1 HEAT repeat SRA1 PF07304.11 CDJ37036.1 - 0.098 12.4 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Vac14_Fab1_bd PF12755.7 CDJ37036.1 - 0.15 12.7 0.9 4.9 7.8 0.1 3.3 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region P53 PF00870.18 CDJ37036.1 - 0.22 11.2 0.1 0.44 10.3 0.1 1.4 1 0 0 1 1 1 0 P53 DNA-binding domain Adap_comp_sub PF00928.21 CDJ37037.1 - 2.7e-85 285.9 0.0 3.3e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDJ37037.1 - 3e-05 24.0 0.2 5.9e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DIM1 PF02966.16 CDJ37038.1 - 2.4e-62 208.6 1.3 2.8e-62 208.4 1.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CDJ37038.1 - 0.0025 17.8 0.1 0.0034 17.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin DNA_photolyase PF00875.18 CDJ37039.1 - 3.1e-16 59.8 0.1 5.8e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase CMS1 PF14617.6 CDJ37039.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Mito_carr PF00153.27 CDJ37040.1 - 3.1e-31 107.2 7.8 8.8e-11 41.6 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein Kinase-like PF14531.6 CDJ37041.1 - 1.8e-17 63.6 0.0 2.6e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RabGAP-TBC PF00566.18 CDJ37042.1 - 5.1e-31 108.0 3.2 5.4e-30 104.7 0.1 2.8 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Beta-lactamase PF00144.24 CDJ37043.1 - 2.3e-39 135.6 0.0 2.5e-35 122.3 0.0 3.2 3 0 0 3 3 3 3 Beta-lactamase ABC1 PF03109.16 CDJ37043.1 - 9.5e-24 83.9 0.0 2e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.11 CDJ37043.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) MFS_1 PF07690.16 CDJ37044.1 - 1.2e-12 47.5 45.5 6.9e-09 35.1 27.3 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 CDJ37045.1 - 7.4e-24 84.5 0.0 4.7e-23 81.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ37045.1 - 1.2e-22 80.6 0.0 1.8e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ37045.1 - 0.00011 21.6 0.0 0.00021 20.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ37045.1 - 0.0087 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family KH_1 PF00013.29 CDJ37046.1 - 3.2e-41 139.0 0.1 1.6e-11 43.8 0.2 5.9 6 0 0 6 6 6 4 KH domain KH_2 PF07650.17 CDJ37046.1 - 0.013 15.3 0.0 1.7 8.6 0.0 3.1 3 0 0 3 3 3 0 KH domain DnaJ PF00226.31 CDJ37047.1 - 7.2e-10 38.9 0.0 1.9e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Aminotran_3 PF00202.21 CDJ37048.1 - 3.5e-119 398.1 0.0 4.1e-119 397.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CDJ37048.1 - 0.0024 17.1 0.0 0.0046 16.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II EFTUD2 PF16004.5 CDJ37049.1 - 9.2e-31 107.0 0.4 9.2e-31 107.0 0.4 3.0 3 0 0 3 3 3 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus GTP_EFTU PF00009.27 CDJ37049.1 - 2.3e-30 105.6 0.0 1.5e-28 99.7 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CDJ37049.1 - 3e-22 78.5 0.0 6.8e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CDJ37049.1 - 1.8e-19 69.7 0.0 4.3e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 CDJ37049.1 - 1.3e-06 28.7 0.0 3.3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CDJ37049.1 - 2.5e-05 24.3 0.0 6.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II AAA_33 PF13671.6 CDJ37049.1 - 0.034 14.3 0.4 3.1 7.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 CDJ37049.1 - 0.18 11.9 0.0 0.71 10.0 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF4667 PF15700.5 CDJ37049.1 - 0.68 10.0 10.4 0.18 11.8 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Presenilin PF01080.17 CDJ37049.1 - 4.4 6.0 5.0 16 4.2 0.5 2.1 2 0 0 2 2 2 0 Presenilin Topoisom_bac PF01131.20 CDJ37051.1 - 2.9e-101 339.5 0.0 3.6e-101 339.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CDJ37051.1 - 1.7e-09 37.9 0.0 3.4e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Coprogen_oxidas PF01218.18 CDJ37051.1 - 1.4e-06 27.3 0.1 2.4e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase ANAPC4_WD40 PF12894.7 CDJ37052.1 - 1.8e-09 37.8 0.4 0.13 12.6 0.0 4.7 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 CDJ37052.1 - 0.021 14.6 0.1 0.07 13.0 0.1 2.0 1 0 0 1 1 1 0 HIRA B motif Pribosyltran_N PF13793.6 CDJ37055.1 - 3.6e-47 159.1 0.1 1.6e-46 157.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CDJ37055.1 - 1.1e-34 120.0 1.1 2e-34 119.3 1.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CDJ37055.1 - 1.3e-12 47.5 0.1 2.5e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CDJ37055.1 - 0.0071 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ResIII PF04851.15 CDJ37056.1 - 0.038 14.0 0.5 0.056 13.4 0.5 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Maf1 PF09174.10 CDJ37058.1 - 4.8e-26 92.0 0.0 1.9e-21 77.0 0.0 2.1 2 0 0 2 2 2 2 Maf1 regulator DER1 PF04511.15 CDJ37059.1 - 2.9e-31 108.9 2.3 3.5e-31 108.6 2.3 1.0 1 0 0 1 1 1 1 Der1-like family ATP-synt_ab PF00006.25 CDJ37061.1 - 1.1e-72 244.2 0.0 1.6e-72 243.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CDJ37061.1 - 1.5e-46 157.8 0.8 2.5e-46 157.1 0.8 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CDJ37061.1 - 2.9e-13 50.1 2.3 7.5e-13 48.8 2.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 CDJ37061.1 - 0.00046 20.3 0.4 0.0011 19.1 0.4 1.6 1 0 0 1 1 1 1 HAS barrel domain MEF2_binding PF09047.10 CDJ37061.1 - 0.056 13.3 0.4 0.15 11.9 0.4 1.8 1 0 0 1 1 1 0 MEF2 binding TniB PF05621.11 CDJ37061.1 - 0.11 11.9 0.0 0.4 10.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein Roc PF08477.13 CDJ37061.1 - 0.13 12.5 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ISN1 PF06437.11 CDJ37062.1 - 5e-22 78.4 0.0 5.3e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Mem_trans PF03547.18 CDJ37064.1 - 0.029 12.8 5.3 0.066 11.6 5.3 1.5 1 0 0 1 1 1 0 Membrane transport protein CNDH2_C PF16858.5 CDJ37064.1 - 0.27 11.1 27.6 0.015 15.2 5.7 3.5 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2387 PF09526.10 CDJ37065.1 - 1.1 9.5 3.2 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) DUF4404 PF14357.6 CDJ37065.1 - 3.1 8.5 12.0 0.18 12.5 6.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Ldh_1_N PF00056.23 CDJ37067.1 - 1.2e-24 87.0 0.1 2.2e-24 86.1 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CDJ37067.1 - 2.7e-24 86.0 0.0 4.1e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 CDJ37067.1 - 0.00017 21.2 0.1 0.00057 19.5 0.0 1.8 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase HTH_31 PF13560.6 CDJ37067.1 - 0.019 15.3 5.8 0.025 14.9 0.4 3.3 4 0 0 4 4 4 0 Helix-turn-helix domain HTH_18 PF12833.7 CDJ37067.1 - 0.024 14.9 0.0 0.062 13.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain FAP PF07174.11 CDJ37067.1 - 0.12 11.8 19.7 0.18 11.2 19.7 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CCDC53 PF10152.9 CDJ37067.1 - 0.92 9.9 2.0 1.5 9.2 2.0 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex IPP-2 PF04979.14 CDJ37068.1 - 2.2e-11 44.6 2.4 2.3e-11 44.5 2.4 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF1772 PF08592.11 CDJ37068.1 - 0.002 18.5 1.9 0.0023 18.3 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Phage_holin_3_6 PF07332.11 CDJ37068.1 - 0.0029 17.6 8.3 0.0041 17.1 8.3 1.2 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Tic110 PF16940.5 CDJ37068.1 - 0.0041 15.7 4.8 0.0044 15.6 4.8 1.1 1 0 0 1 1 1 1 Chloroplast envelope transporter FHIPEP PF00771.20 CDJ37068.1 - 0.0051 15.3 3.8 0.0054 15.3 3.8 1.0 1 0 0 1 1 1 1 FHIPEP family Peptidase_S49_N PF08496.10 CDJ37068.1 - 0.0089 16.1 3.5 0.011 15.9 3.5 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Ureide_permease PF07168.11 CDJ37068.1 - 0.017 13.9 1.0 0.019 13.7 1.0 1.1 1 0 0 1 1 1 0 Ureide permease DUF719 PF05334.13 CDJ37068.1 - 0.042 14.1 2.9 0.051 13.8 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF719) PKI PF02827.16 CDJ37068.1 - 0.074 13.3 3.0 0.13 12.5 3.0 1.4 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor HEV_ORF1 PF02444.16 CDJ37068.1 - 0.08 13.5 1.4 0.11 13.1 1.4 1.2 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) HemX PF04375.14 CDJ37068.1 - 0.085 12.1 13.9 0.1 11.9 13.9 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4199 PF13858.6 CDJ37068.1 - 0.09 13.2 1.1 0.11 12.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) R_equi_Vir PF05526.11 CDJ37068.1 - 0.11 12.4 5.5 0.14 12.0 5.5 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein EOS1 PF12326.8 CDJ37068.1 - 0.18 11.7 0.3 0.2 11.6 0.3 1.1 1 0 0 1 1 1 0 N-glycosylation protein Dpy19 PF10034.9 CDJ37068.1 - 0.24 9.5 0.2 0.24 9.5 0.2 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation TFIIA PF03153.13 CDJ37068.1 - 0.28 11.1 12.4 0.28 11.2 12.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TALPID3 PF15324.6 CDJ37068.1 - 0.6 7.7 14.7 0.79 7.3 14.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target CT_C_D PF02682.16 CDJ37068.1 - 1 9.1 4.7 1.2 8.8 4.7 1.1 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D RskA PF10099.9 CDJ37068.1 - 5.5 7.2 22.1 14 5.9 22.1 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SLATT_1 PF18181.1 CDJ37068.1 - 6.1 6.8 14.9 8.4 6.3 14.7 1.3 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 HA2 PF04408.23 CDJ37068.1 - 7.8 6.8 8.5 12 6.2 8.4 1.5 1 1 0 1 1 1 0 Helicase associated domain (HA2) Ribosomal_60s PF00428.19 CDJ37069.1 - 0.0049 17.4 24.3 0.075 13.6 7.5 2.8 2 0 0 2 2 2 2 60s Acidic ribosomal protein STIMATE PF12400.8 CDJ37070.1 - 1.3e-29 103.3 0.4 1.9e-29 102.8 0.4 1.2 1 0 0 1 1 1 1 STIMATE family TFIIA PF03153.13 CDJ37070.1 - 0.18 11.8 14.7 0.19 11.7 14.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ37070.1 - 0.33 11.2 7.9 0.27 11.5 6.2 1.7 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF3523 PF12037.8 CDJ37071.1 - 2.7e-80 269.6 34.0 2.7e-80 269.6 34.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3523) AAA PF00004.29 CDJ37071.1 - 1.4e-17 64.4 0.0 5.2e-17 62.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ37071.1 - 1e-06 29.2 0.1 1e-06 29.2 0.1 3.7 2 2 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 CDJ37071.1 - 7.7e-06 25.7 0.0 2.3e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CDJ37071.1 - 4.3e-05 23.7 0.0 4.3e-05 23.7 0.0 2.8 2 1 0 2 2 1 1 AAA domain Rad17 PF03215.15 CDJ37071.1 - 0.00033 20.6 0.4 0.0013 18.7 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_lid_3 PF17862.1 CDJ37071.1 - 0.0013 18.5 0.1 0.0047 16.7 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ37071.1 - 0.003 17.6 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ37071.1 - 0.0042 17.4 8.7 0.0043 17.3 0.0 3.8 2 2 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 CDJ37071.1 - 0.0059 16.0 0.0 0.02 14.3 0.0 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 CDJ37071.1 - 0.0084 16.2 0.1 0.044 13.9 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain TsaE PF02367.17 CDJ37071.1 - 0.01 15.8 0.0 0.031 14.3 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 CDJ37071.1 - 0.015 15.2 0.0 0.044 13.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytochrom_C1 PF02167.15 CDJ37071.1 - 0.02 14.6 0.6 0.043 13.5 0.6 1.5 1 0 0 1 1 1 0 Cytochrome C1 family AAA_7 PF12775.7 CDJ37071.1 - 0.041 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CDJ37071.1 - 0.066 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 CDJ37071.1 - 0.088 12.6 0.0 0.088 12.6 0.0 3.5 3 1 1 4 4 2 0 AAA domain AAA_18 PF13238.6 CDJ37071.1 - 0.1 13.1 0.0 0.1 13.1 0.0 3.4 2 2 1 3 3 2 0 AAA domain AAA_24 PF13479.6 CDJ37071.1 - 0.11 12.2 1.4 0.24 11.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain SDH_beta PF03315.15 CDJ37071.1 - 0.26 11.7 3.3 0.22 11.9 0.2 2.4 1 1 0 2 2 2 0 Serine dehydratase beta chain PepSY_TM PF03929.16 CDJ37071.1 - 0.44 10.2 3.0 22 4.6 2.1 2.3 2 0 0 2 2 2 0 PepSY-associated TM region AAA_25 PF13481.6 CDJ37071.1 - 1.6 8.2 6.6 2.6 7.6 0.0 2.9 2 1 1 3 3 3 0 AAA domain TFIIA PF03153.13 CDJ37071.1 - 2.9 7.8 21.8 1.1 9.2 19.3 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Met_10 PF02475.16 CDJ37072.1 - 2.2e-11 43.9 0.0 3.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 CDJ37072.1 - 0.071 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain SUIM_assoc PF16619.5 CDJ37072.1 - 0.25 11.4 5.5 1.1 9.4 1.8 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Utp12 PF04003.12 CDJ37072.1 - 0.28 11.5 2.4 0.45 10.9 1.4 1.8 2 0 0 2 2 2 0 Dip2/Utp12 Family AAA_21 PF13304.6 CDJ37073.1 - 0.0089 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Pkinase PF00069.25 CDJ37074.1 - 6.1e-12 45.5 0.0 4.4e-05 23.0 0.0 3.7 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37074.1 - 3.6e-05 23.2 0.0 0.12 11.6 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ37074.1 - 0.0031 16.9 14.7 0.13 11.5 0.3 3.8 2 1 1 3 3 3 2 Kinase-like PBP1_TM PF14812.6 CDJ37074.1 - 0.034 14.5 3.7 0.1 13.0 3.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CSRNP_N PF16019.5 CDJ37074.1 - 0.048 13.6 14.3 0.021 14.7 8.4 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus FAM176 PF14851.6 CDJ37074.1 - 5 6.8 14.6 0.38 10.4 4.5 2.8 3 0 0 3 3 3 0 FAM176 family VEFS-Box PF09733.9 CDJ37074.1 - 6.1 6.7 10.7 12 5.7 10.7 1.4 1 0 0 1 1 1 0 VEFS-Box of polycomb protein LRR_4 PF12799.7 CDJ37075.1 - 3.4e-11 43.2 13.7 1.1e-05 25.7 0.9 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ37075.1 - 1.5e-09 37.5 27.1 4.3e-05 23.2 3.6 3.2 1 1 3 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 CDJ37075.1 - 4.9e-07 29.4 2.0 4.4e-06 26.3 1.7 2.3 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 CDJ37075.1 - 0.0064 16.5 7.8 2 8.7 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich repeat Lin-8 PF03353.15 CDJ37075.1 - 0.077 12.5 4.0 0.11 12.0 4.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spt20 PF12090.8 CDJ37075.1 - 0.21 11.2 12.5 0.34 10.5 12.5 1.4 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 CDJ37075.1 - 0.48 10.0 12.4 0.83 9.2 12.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Miga PF10265.9 CDJ37075.1 - 0.6 9.0 5.6 0.86 8.5 5.6 1.3 1 0 0 1 1 1 0 Mitoguardin Roughex PF06020.11 CDJ37075.1 - 1.6 7.7 4.8 2.4 7.1 4.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CDK2AP PF09806.9 CDJ37075.1 - 7.5 6.5 24.6 19 5.3 24.6 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF155 PF02582.14 CDJ37076.1 - 6e-33 114.4 0.0 2.6e-32 112.3 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Macoilin PF09726.9 CDJ37076.1 - 0.75 8.3 16.4 1.4 7.4 16.4 1.3 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 CDJ37076.1 - 1.2 8.9 21.0 1.7 8.5 21.0 1.3 1 0 0 1 1 1 0 SPX domain TPR_12 PF13424.6 CDJ37077.1 - 3.4e-05 24.0 6.5 0.043 14.1 0.7 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ37077.1 - 0.0028 17.5 4.3 0.14 12.0 0.2 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ37077.1 - 0.0062 16.7 4.2 2.7 8.4 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat RskA PF10099.9 CDJ37078.1 - 1e-07 32.4 8.0 0.00012 22.4 0.0 3.3 1 1 2 3 3 3 2 Anti-sigma-K factor rskA CAP_GLY PF01302.25 CDJ37079.1 - 1.4e-09 37.9 0.3 2e-08 34.1 0.3 2.2 1 1 0 1 1 1 1 CAP-Gly domain DUF3506 PF12014.8 CDJ37079.1 - 0.039 14.0 1.2 0.19 11.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) PIP5K PF01504.18 CDJ37079.1 - 0.15 11.3 0.9 0.19 10.9 0.9 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase EIIBC-GUT_N PF03612.14 CDJ37079.1 - 1.3 8.7 3.1 2.2 8.0 0.1 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus ORC_WH_C PF18137.1 CDJ37079.1 - 3.2 7.8 7.1 2.5 8.2 0.5 2.1 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Rpp20 PF12328.8 CDJ37079.1 - 9.5 6.2 7.8 0.99 9.4 0.2 2.1 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Glycos_transf_2 PF00535.26 CDJ37081.1 - 2.5e-22 79.5 0.0 3.8e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ37081.1 - 1.5e-13 51.1 0.3 3.4e-13 50.0 0.3 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CDJ37081.1 - 9.2e-09 34.8 1.1 2.9e-08 33.3 0.2 2.1 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase CDtoxinA PF03498.14 CDJ37081.1 - 0.0021 17.7 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 1 Cytolethal distending toxin A/C domain RicinB_lectin_2 PF14200.6 CDJ37081.1 - 0.0025 18.5 0.0 0.3 11.8 0.0 2.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like TFIIA PF03153.13 CDJ37081.1 - 0.93 9.4 10.1 0.14 12.1 6.6 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DnaJ PF00226.31 CDJ37082.1 - 2e-09 37.4 2.3 9e-07 28.9 0.0 3.3 3 0 0 3 3 3 2 DnaJ domain IncE PF17627.2 CDJ37082.1 - 0.013 15.5 2.5 0.022 14.8 0.5 2.4 2 0 0 2 2 2 0 Inclusion membrane protein E DUF5344 PF17279.2 CDJ37082.1 - 0.082 13.5 6.3 0.11 13.0 2.9 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5344) PAS PF00989.25 CDJ37082.1 - 0.28 11.2 2.2 0.51 10.4 0.5 2.3 2 0 0 2 2 2 0 PAS fold Pkinase PF00069.25 CDJ37083.1 - 3.6e-60 203.6 0.9 3.3e-52 177.5 0.4 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37083.1 - 2e-27 96.1 0.4 1.2e-21 77.2 0.2 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ37083.1 - 0.031 13.2 2.4 0.1 11.5 2.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain PAT1 PF09770.9 CDJ37083.1 - 1.3 7.2 23.1 2 6.6 23.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 CDJ37083.1 - 3.1 7.7 32.7 5.7 6.8 32.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ37083.1 - 3.9 6.2 8.6 5.6 5.6 8.6 1.1 1 0 0 1 1 1 0 Presenilin Metallophos PF00149.28 CDJ37084.1 - 0.0017 18.9 0.0 0.0028 18.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPI_Ypi1 PF07491.11 CDJ37086.1 - 1.5e-21 75.9 0.1 1.5e-21 75.9 0.1 1.8 2 0 0 2 2 2 1 Protein phosphatase inhibitor KI67R PF08065.12 CDJ37086.1 - 0.00097 19.7 0.9 0.0013 19.3 0.9 1.2 1 0 0 1 1 1 1 KI67R (NUC007) repeat Presenilin PF01080.17 CDJ37086.1 - 1.2 7.8 2.4 1.4 7.6 2.4 1.0 1 0 0 1 1 1 0 Presenilin Dehydrin PF00257.19 CDJ37086.1 - 7.9 7.0 12.4 15 6.1 12.4 1.7 1 1 0 1 1 1 0 Dehydrin Kinase-like PF14531.6 CDJ37087.1 - 7.3e-06 25.5 0.0 0.00029 20.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.25 CDJ37087.1 - 3.3e-05 23.4 0.0 5.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37087.1 - 0.0022 17.3 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ37088.1 - 2.8e-08 33.5 0.0 4.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ37088.1 - 2.3e-05 23.8 0.0 3.6e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ37088.1 - 0.00042 19.7 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ37089.1 - 8.6e-10 38.4 0.0 1.6e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ37089.1 - 1.9e-06 27.4 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ37089.1 - 7.2e-05 22.2 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ37090.1 - 2.6e-12 46.7 0.0 7.2e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 CDJ37090.1 - 5.3e-06 25.9 0.0 0.00082 18.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_Tyr PF07714.17 CDJ37090.1 - 6.9e-06 25.5 0.0 1.4e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase U5_2-snRNA_bdg PF10597.9 CDJ37090.1 - 0.019 15.0 0.0 0.075 13.1 0.0 1.9 2 0 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 HlyIII PF03006.20 CDJ37091.1 - 8.2e-07 29.0 3.3 1.2e-06 28.5 3.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3591 PF12157.8 CDJ37092.1 - 5.6e-25 87.9 0.0 2.3e-13 49.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3591) Bromodomain PF00439.25 CDJ37092.1 - 3.3e-16 59.1 0.0 6.1e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain zf-CCHC_6 PF15288.6 CDJ37092.1 - 0.0041 16.9 1.3 0.014 15.2 1.3 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CDJ37092.1 - 0.019 15.1 0.4 0.056 13.5 0.4 1.8 1 0 0 1 1 1 0 Zinc knuckle DUF5435 PF17503.2 CDJ37092.1 - 0.18 11.5 1.5 0.47 10.1 1.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5435) DUF1963 PF09234.10 CDJ37093.1 - 0.063 13.7 0.2 2 8.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1963) DUF4520 PF15016.6 CDJ37093.1 - 0.12 12.4 0.1 21 5.3 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) SUIM_assoc PF16619.5 CDJ37093.1 - 0.19 11.8 21.9 0.62 10.2 0.0 4.6 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Patched PF02460.18 CDJ37094.1 - 3.9e-105 352.7 0.4 2.2e-66 224.5 1.2 3.0 3 0 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 CDJ37094.1 - 6.5e-28 97.5 3.0 6.5e-28 97.5 3.0 2.1 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 CDJ37094.1 - 3.4e-05 21.7 11.2 6e-05 20.9 11.2 1.3 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF4525 PF15027.6 CDJ37094.1 - 0.13 12.0 0.8 0.38 10.5 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Macoilin PF09726.9 CDJ37094.1 - 0.17 10.5 22.1 0.29 9.6 22.1 1.3 1 0 0 1 1 1 0 Macoilin family Phage_holin_3_5 PF16085.5 CDJ37094.1 - 6.7 6.9 8.6 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Bacteriophage holin Hol, superfamily III BshC PF10079.9 CDJ37095.1 - 0.091 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC cEGF PF12662.7 CDJ37096.1 - 0.034 14.1 0.1 0.075 13.0 0.1 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like FAM176 PF14851.6 CDJ37096.1 - 0.078 12.6 0.0 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 FAM176 family Mid2 PF04478.12 CDJ37096.1 - 0.12 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EGF PF00008.27 CDJ37096.1 - 0.15 12.4 6.1 0.26 11.6 6.1 1.5 1 0 0 1 1 1 0 EGF-like domain Thyroglob_assoc PF16597.5 CDJ37096.1 - 0.17 12.2 0.3 0.17 12.2 0.3 2.4 2 0 0 2 2 2 0 Thyroglobulin_1 repeat associated disordered domain TrbC PF04956.13 CDJ37096.1 - 2.8 8.2 4.7 5.4 7.3 0.1 2.3 2 0 0 2 2 2 0 TrbC/VIRB2 family TMEM43 PF07787.12 CDJ37097.1 - 8.2e-18 64.7 0.0 1.3e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 43 DUF3096 PF11295.8 CDJ37097.1 - 0.66 9.7 4.6 1.6 8.4 4.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3096) Polysacc_deac_2 PF04748.13 CDJ37098.1 - 0.68 9.1 4.2 0.79 8.9 0.1 2.8 3 0 0 3 3 3 0 Divergent polysaccharide deacetylase Zip PF02535.22 CDJ37098.1 - 1.2 8.3 4.5 2.8 7.1 4.5 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Abhydrolase_6 PF12697.7 CDJ37100.1 - 2.3e-11 44.7 0.0 1.7e-09 38.6 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ37100.1 - 1e-07 31.9 0.5 0.00078 19.2 0.1 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.13 CDJ37100.1 - 0.12 12.1 0.3 0.58 9.8 0.1 2.0 2 0 0 2 2 2 0 PGAP1-like protein Syntaphilin PF15290.6 CDJ37100.1 - 2.6 7.6 6.0 7.3 6.2 6.0 1.7 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Oxysterol_BP PF01237.18 CDJ37101.1 - 2.1e-91 306.5 10.3 1.1e-74 251.5 0.0 3.2 2 1 1 3 3 3 2 Oxysterol-binding protein PH PF00169.29 CDJ37101.1 - 1.5e-12 47.9 0.2 5.7e-12 46.1 0.2 2.0 2 0 0 2 2 2 1 PH domain Prp19 PF08606.11 CDJ37101.1 - 0.051 13.6 5.8 0.19 11.7 5.8 2.0 1 0 0 1 1 1 0 Prp19/Pso4-like betaPIX_CC PF16523.5 CDJ37101.1 - 0.11 12.4 3.6 0.35 10.7 3.6 1.9 1 0 0 1 1 1 0 betaPIX coiled coil DUF4524 PF15025.6 CDJ37104.1 - 0.075 12.8 1.3 1.4 8.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4524) RT_RNaseH PF17917.1 CDJ37105.1 - 2.7e-16 59.7 0.3 3.4e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ37105.1 - 4.5e-06 26.6 0.0 8.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CDJ37105.1 - 0.00085 19.1 0.0 0.00095 19.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like RVP_2 PF08284.11 CDJ37106.1 - 2.4e-07 30.6 0.0 0.0046 16.7 0.0 2.3 1 1 1 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ37106.1 - 2e-05 25.1 0.0 8e-05 23.1 0.0 1.9 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ37106.1 - 4.4e-05 24.0 0.0 0.00011 22.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ37106.1 - 0.092 13.1 0.0 1.9 8.9 0.0 2.7 2 1 1 3 3 3 0 Retroviral aspartyl protease zf-CCHC PF00098.23 CDJ37107.1 - 5.4e-07 29.4 11.0 8.2e-05 22.5 2.8 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ37107.1 - 0.0016 18.3 9.4 0.0018 18.1 0.5 2.4 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 CDJ37107.1 - 0.0069 16.6 0.0 0.022 15.0 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zinc-ribbons_6 PF07191.12 CDJ37107.1 - 0.14 12.1 1.4 0.32 11.0 1.4 1.5 1 0 0 1 1 1 0 zinc-ribbons zf-CCHC_4 PF14392.6 CDJ37107.1 - 0.18 11.5 6.8 0.25 11.1 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ37107.1 - 0.87 9.6 8.2 0.15 12.1 1.4 2.4 1 1 1 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 CDJ37107.1 - 1.1 9.7 9.7 4.5 7.7 9.7 2.0 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC_2 PF13696.6 CDJ37107.1 - 8.4 6.3 11.5 0.3 11.0 2.6 2.4 2 0 0 2 2 2 0 Zinc knuckle RVP_2 PF08284.11 CDJ37108.1 - 1.7e-07 31.0 0.0 0.0039 17.0 0.0 2.3 1 1 1 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ37108.1 - 1.5e-05 25.4 0.0 7.5e-05 23.2 0.0 2.0 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ37108.1 - 3.5e-05 24.4 0.0 9.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ37108.1 - 0.098 13.0 0.0 1.6 9.1 0.0 2.5 1 1 1 2 2 2 0 Retroviral aspartyl protease LBP_C PF17386.2 CDJ37109.1 - 0.011 15.6 2.0 3.1 7.7 0.1 2.4 2 0 0 2 2 2 0 Lacto-N-biose phosphorylase C-terminal domain Frag1 PF10277.9 CDJ37109.1 - 0.1 12.1 13.0 0.17 11.4 13.0 1.3 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF4271 PF14093.6 CDJ37109.1 - 0.19 11.6 11.8 0.74 9.7 3.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) CstA PF02554.14 CDJ37109.1 - 0.7 8.7 14.4 1 8.2 14.4 1.2 1 0 0 1 1 1 0 Carbon starvation protein CstA Cortexin PF11057.8 CDJ37109.1 - 1.7 8.5 7.1 7.2 6.5 0.1 2.6 3 0 0 3 3 3 0 Cortexin of kidney DUF2207 PF09972.9 CDJ37109.1 - 3.4 6.3 8.6 8.8 5.0 8.6 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) CHZ PF09649.10 CDJ37109.1 - 5.7 6.5 12.3 4.1 6.9 0.1 3.3 3 0 0 3 3 3 0 Histone chaperone domain CHZ SF-assemblin PF06705.11 CDJ37110.1 - 0.0012 18.3 30.8 0.015 14.7 24.0 3.4 1 1 1 2 2 2 2 SF-assemblin/beta giardin Nipped-B_C PF12830.7 CDJ37110.1 - 0.12 12.3 13.5 0.092 12.7 1.7 2.2 1 1 1 2 2 2 0 Sister chromatid cohesion C-terminus EST1_DNA_bind PF10373.9 CDJ37110.1 - 0.23 10.9 6.2 0.33 10.4 6.2 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain FAST_2 PF08368.12 CDJ37110.1 - 5.2 7.9 9.6 3.3 8.6 0.5 3.3 2 1 1 3 3 3 0 FAST kinase-like protein, subdomain 2 RecG_N PF17190.4 CDJ37110.1 - 6.5 7.6 17.7 8.1 7.3 1.5 3.8 1 1 3 4 4 4 0 RecG N-terminal helical domain TFIIA PF03153.13 CDJ37111.1 - 0.0049 16.9 19.1 0.006 16.6 19.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 CDJ37111.1 - 0.03 13.3 29.0 0.04 12.9 29.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RAMP4 PF06624.12 CDJ37111.1 - 0.091 12.8 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 PAT1 PF09770.9 CDJ37111.1 - 1 7.5 16.6 1.2 7.3 16.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Methyltransf_34 PF11312.8 CDJ37112.1 - 8.8 5.5 7.0 13 4.9 7.0 1.4 1 1 0 1 1 1 0 Putative SAM-dependent methyltransferase Cnd1 PF12717.7 CDJ37113.1 - 0.00014 22.0 0.2 0.025 14.6 0.0 3.2 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Dehydrin PF00257.19 CDJ37114.1 - 0.15 12.6 0.4 0.35 11.4 0.4 1.6 1 0 0 1 1 1 0 Dehydrin Cyt_bd_oxida_II PF02322.15 CDJ37115.1 - 0.0066 15.9 4.6 1.9 7.8 3.4 2.1 2 0 0 2 2 2 2 Cytochrome bd terminal oxidase subunit II DUF4834 PF16118.5 CDJ37115.1 - 1.1 10.3 0.0 1.1 10.3 0.0 2.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Pyr_redox_2 PF07992.14 CDJ37116.1 - 5.6e-05 22.5 0.0 0.011 15.0 0.0 1.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDJ37116.1 - 0.00073 19.6 2.0 0.0074 16.3 0.1 3.1 2 1 0 3 3 3 1 FAD-NAD(P)-binding Methyltransf_34 PF11312.8 CDJ37116.1 - 0.013 14.7 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase FAD_binding_3 PF01494.19 CDJ37116.1 - 0.014 14.7 1.4 0.026 13.8 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 CDJ37116.1 - 0.023 14.3 1.0 14 5.1 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ37116.1 - 0.028 14.6 0.1 0.028 14.6 0.1 2.2 2 1 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Tim54 PF11711.8 CDJ37116.1 - 0.048 12.4 0.1 0.085 11.6 0.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HI0933_like PF03486.14 CDJ37116.1 - 0.12 11.0 0.1 0.12 11.0 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 CDJ37116.1 - 0.13 11.4 0.0 0.28 10.4 0.0 1.5 2 0 0 2 2 2 0 Thi4 family PAT1 PF09770.9 CDJ37116.1 - 0.41 8.9 9.6 0.46 8.7 9.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2722 PF10846.8 CDJ37116.1 - 0.43 9.5 16.9 3.3 6.5 13.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ37116.1 - 2.1 8.3 27.1 3.7 7.4 27.1 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ37116.1 - 5.8 8.0 7.3 3.4 8.7 4.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3292 PF11696.8 CDJ37116.1 - 8.7 4.6 6.4 2 6.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) Spt20 PF12090.8 CDJ37117.1 - 2.5e-05 24.0 19.0 0.0013 18.4 6.4 2.1 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 CDJ37117.1 - 0.00079 18.5 15.1 0.00087 18.3 3.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) PIP5K PF01504.18 CDJ37117.1 - 0.049 12.9 0.1 0.069 12.4 0.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Suf PF05843.14 CDJ37117.1 - 0.55 10.2 9.4 1.7 8.6 4.2 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) MPM1 PF17234.2 CDJ37117.1 - 3.2 8.0 10.1 3.4 7.9 0.8 2.5 2 1 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Roughex PF06020.11 CDJ37117.1 - 6.2 5.8 12.8 0.23 10.5 1.5 2.2 2 0 0 2 2 2 0 Drosophila roughex protein Sec62 PF03839.16 CDJ37117.1 - 6.6 6.2 5.9 2.5 7.6 0.6 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 zf-C3HC4_3 PF13920.6 CDJ37118.1 - 3.4e-08 33.2 8.8 3.4e-08 33.2 8.8 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ37118.1 - 1.2e-06 28.3 8.4 1.2e-06 28.3 8.4 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ37118.1 - 2.2e-06 27.4 10.4 6.8e-06 25.8 10.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1645 PF07816.11 CDJ37118.1 - 1.7e-05 25.5 34.2 0.00016 22.3 12.7 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1645) zf-RING_2 PF13639.6 CDJ37118.1 - 2e-05 24.8 10.1 2e-05 24.8 10.1 3.2 3 0 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 CDJ37118.1 - 5.3e-05 23.0 9.6 5.3e-05 23.0 9.6 2.5 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 SR-25 PF10500.9 CDJ37118.1 - 0.00011 21.9 12.4 0.00011 21.9 12.4 4.3 3 1 1 4 4 2 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ37118.1 - 0.0022 16.2 14.3 0.0022 16.2 14.3 2.7 2 1 0 2 2 1 1 AF-4 proto-oncoprotein zf-RING_5 PF14634.6 CDJ37118.1 - 0.0023 17.8 8.9 0.0023 17.8 8.9 2.9 2 1 1 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ37118.1 - 0.0064 16.5 10.3 0.033 14.2 10.3 2.4 1 0 0 1 1 1 1 RING-type zinc-finger Utp14 PF04615.13 CDJ37118.1 - 0.15 10.6 33.7 0.014 14.1 13.8 2.4 2 0 0 2 2 2 0 Utp14 protein Ecl1 PF12855.7 CDJ37118.1 - 0.66 11.1 30.3 1.1 10.5 11.8 3.4 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins Peptidase_S64 PF08192.11 CDJ37118.1 - 1 7.8 37.5 5.7 5.3 21.8 2.9 3 0 0 3 3 3 0 Peptidase family S64 Pox_A12 PF04651.13 CDJ37118.1 - 4.2 7.4 15.8 6.6 6.7 2.3 2.4 2 0 0 2 2 2 0 Poxvirus A12 protein Filament_head PF04732.14 CDJ37118.1 - 7.1 7.6 33.8 2.3 9.2 8.4 3.4 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region TFIIA PF03153.13 CDJ37119.1 - 0.00076 19.6 36.9 0.00076 19.6 36.9 5.1 4 1 1 5 5 5 3 Transcription factor IIA, alpha/beta subunit FleQ PF06490.11 CDJ37119.1 - 1.1 9.6 10.7 0.24 11.8 0.2 3.9 3 0 0 3 3 3 0 Flagellar regulatory protein FleQ S1-P1_nuclease PF02265.16 CDJ37120.1 - 2.7e-18 66.7 0.0 3.9e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease DUF3605 PF12239.8 CDJ37120.1 - 0.015 15.6 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) DUF429 PF04250.13 CDJ37120.1 - 0.032 14.0 0.1 0.074 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF429) Dapper PF15268.6 CDJ37121.1 - 1.6 7.5 49.4 0.0049 15.8 36.1 2.1 2 0 0 2 2 2 0 Dapper Pkinase_fungal PF17667.1 CDJ37121.1 - 2.5 6.8 12.6 4.3 6.0 12.6 1.4 1 0 0 1 1 1 0 Fungal protein kinase DUF3446 PF11928.8 CDJ37122.1 - 0.0067 16.7 11.1 0.0098 16.2 11.1 1.3 1 0 0 1 1 1 1 Early growth response N-terminal domain DUF4667 PF15700.5 CDJ37122.1 - 0.0095 16.1 2.1 0.011 15.9 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) FxsA PF04186.13 CDJ37122.1 - 0.012 15.7 0.1 0.016 15.3 0.1 1.1 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein CYSTM PF12734.7 CDJ37122.1 - 0.023 15.0 2.7 0.14 12.5 3.6 1.9 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Lin-8 PF03353.15 CDJ37122.1 - 0.13 11.8 1.0 0.15 11.6 1.0 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2207 PF09972.9 CDJ37122.1 - 0.25 10.1 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pex14_N PF04695.13 CDJ37123.1 - 0.14 12.9 6.4 0.18 12.4 6.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ37123.1 - 5.9 6.8 14.8 6.7 6.6 14.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aldedh PF00171.22 CDJ37125.1 - 4.5e-09 35.3 0.1 0.0011 17.6 0.0 2.9 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Unstab_antitox PF09720.10 CDJ37125.1 - 0.021 14.9 0.1 0.052 13.6 0.1 1.7 1 0 0 1 1 1 0 Putative addiction module component Acetone_carb_G PF08882.11 CDJ37125.1 - 0.13 12.4 0.2 0.28 11.3 0.2 1.6 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit UMP1 PF05348.11 CDJ37126.1 - 1.1e-11 45.0 0.0 1.7e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 AAA PF00004.29 CDJ37127.1 - 4.6e-42 143.6 0.0 8.7e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ37127.1 - 1.7e-12 46.9 0.4 3.7e-12 45.9 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CDJ37127.1 - 9e-09 35.2 0.1 1.8e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CDJ37127.1 - 2.8e-07 31.1 0.3 0.00014 22.3 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 CDJ37127.1 - 3.1e-07 30.7 0.0 8.5e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CDJ37127.1 - 5.5e-06 26.4 0.1 7.8e-05 22.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDJ37127.1 - 1.2e-05 25.1 0.0 3.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDJ37127.1 - 0.00024 21.4 0.9 0.024 14.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 CDJ37127.1 - 0.0006 19.6 0.1 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDJ37127.1 - 0.00092 19.0 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 CDJ37127.1 - 0.0011 18.5 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 CDJ37127.1 - 0.0015 18.2 0.1 0.0064 16.2 0.0 2.0 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 CDJ37127.1 - 0.0015 19.1 0.2 0.0083 16.7 0.0 2.4 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.13 CDJ37127.1 - 0.0017 17.7 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 CDJ37127.1 - 0.0024 18.2 0.0 0.0054 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 CDJ37127.1 - 0.0039 16.6 0.1 0.0073 15.7 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 CDJ37127.1 - 0.0058 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 CDJ37127.1 - 0.0063 16.5 0.1 0.016 15.2 0.0 1.7 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CDJ37127.1 - 0.0088 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 CDJ37127.1 - 0.0099 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CDJ37127.1 - 0.011 15.2 0.1 0.026 14.0 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 CDJ37127.1 - 0.013 15.7 0.0 0.053 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CDJ37127.1 - 0.017 15.1 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CDJ37127.1 - 0.021 15.1 0.1 0.067 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CDJ37127.1 - 0.03 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 CDJ37127.1 - 0.03 13.7 0.0 0.085 12.2 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.6 CDJ37127.1 - 0.041 13.5 0.1 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CDJ37127.1 - 0.078 12.8 2.6 0.19 11.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 CDJ37127.1 - 0.1 12.5 0.1 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 CDJ37127.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.6 CDJ37127.1 - 0.13 12.4 0.0 0.56 10.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 CDJ37128.1 - 1.9e-35 122.3 0.1 1.2e-18 67.9 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 CDJ37128.1 - 8.8e-20 71.5 7.2 8.8e-20 71.5 7.2 2.3 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_29 PF13555.6 CDJ37128.1 - 1.8e-08 34.0 0.1 0.0039 16.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ37128.1 - 6.3e-07 29.5 0.2 0.0046 17.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 CDJ37128.1 - 3.7e-05 24.2 0.0 3.7e-05 24.2 0.0 4.6 5 1 1 6 6 2 2 AAA ATPase domain MeaB PF03308.16 CDJ37128.1 - 4.6e-05 22.5 0.2 0.16 10.9 0.0 2.7 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CDJ37128.1 - 5.2e-05 23.8 0.1 0.068 13.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDJ37128.1 - 5.9e-05 22.9 0.1 5.9e-05 22.9 0.1 3.4 4 0 0 4 4 2 1 AAA domain AAA_21 PF13304.6 CDJ37128.1 - 6.2e-05 23.0 3.0 0.046 13.5 0.1 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ATPase_2 PF01637.18 CDJ37128.1 - 0.00015 21.7 0.0 0.097 12.6 0.0 3.0 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 CDJ37128.1 - 0.00019 21.4 1.4 0.64 9.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 CDJ37128.1 - 0.00021 20.4 0.4 0.39 9.7 0.1 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 CDJ37128.1 - 0.0003 21.1 9.7 0.024 14.9 0.0 4.4 5 0 0 5 5 5 2 AAA domain NTPase_1 PF03266.15 CDJ37128.1 - 0.00034 20.6 0.2 0.057 13.3 0.0 2.7 2 0 0 2 2 2 1 NTPase AAA_7 PF12775.7 CDJ37128.1 - 0.00051 19.6 0.1 0.059 12.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 CDJ37128.1 - 0.00064 19.4 0.7 0.14 11.7 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF2722 PF10846.8 CDJ37128.1 - 0.00095 18.2 10.1 0.11 11.5 7.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Viral_helicase1 PF01443.18 CDJ37128.1 - 0.0024 17.7 0.4 0.11 12.2 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 CDJ37128.1 - 0.0026 17.1 0.7 0.22 10.8 0.1 2.6 2 0 0 2 2 2 1 Zeta toxin SMC_N PF02463.19 CDJ37128.1 - 0.0026 17.2 0.0 0.89 8.9 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Gaa1 PF04114.14 CDJ37128.1 - 0.0044 16.1 9.7 0.0054 15.8 7.7 1.9 2 0 0 2 2 2 1 Gaa1-like, GPI transamidase component NACHT PF05729.12 CDJ37128.1 - 0.0046 16.9 4.5 0.4 10.6 0.0 3.3 3 0 0 3 3 3 1 NACHT domain DUF815 PF05673.13 CDJ37128.1 - 0.0056 15.9 0.2 0.22 10.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 CDJ37128.1 - 0.0066 16.8 0.4 0.0066 16.8 0.4 2.8 2 1 0 2 2 1 1 AAA domain Dynamin_N PF00350.23 CDJ37128.1 - 0.0069 16.5 3.0 1.3 9.1 0.1 3.6 3 0 0 3 3 3 1 Dynamin family FtsK_SpoIIIE PF01580.18 CDJ37128.1 - 0.0076 15.6 0.2 1.1 8.6 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 CDJ37128.1 - 0.0093 15.8 0.1 1.1 8.9 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.21 CDJ37128.1 - 0.012 15.0 0.2 2.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CDJ37128.1 - 0.014 15.4 0.2 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CDJ37128.1 - 0.014 15.8 0.2 1.9 8.9 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_23 PF13476.6 CDJ37128.1 - 0.015 15.8 0.2 0.065 13.7 0.1 4.8 5 1 0 5 5 3 0 AAA domain AAA_5 PF07728.14 CDJ37128.1 - 0.016 15.2 1.3 0.37 10.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CDJ37128.1 - 0.022 14.4 0.3 3.2 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CDJ37128.1 - 0.029 14.8 3.1 0.07 13.5 0.1 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 CDJ37128.1 - 0.031 14.0 7.0 0.059 13.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 CDJ37128.1 - 0.055 13.6 0.6 0.41 10.7 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 CDJ37128.1 - 0.094 12.4 0.1 13 5.4 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 CDJ37128.1 - 0.1 12.8 0.0 0.1 12.8 0.0 3.6 5 0 0 5 5 2 0 AAA domain RNA12 PF10443.9 CDJ37128.1 - 0.11 11.3 2.2 0.11 11.2 0.0 2.0 2 0 0 2 2 1 0 RNA12 protein AAA_14 PF13173.6 CDJ37128.1 - 0.13 12.3 0.2 9.8 6.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain Spt20 PF12090.8 CDJ37128.1 - 0.13 11.8 24.9 1.1 8.9 15.9 2.4 2 0 0 2 2 2 0 Spt20 family AAA_24 PF13479.6 CDJ37128.1 - 0.15 11.8 1.7 5.9 6.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain Adeno_IVa2 PF02456.15 CDJ37128.1 - 0.17 10.7 0.9 3 6.6 0.1 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein CobU PF02283.16 CDJ37128.1 - 0.55 9.8 3.5 1.9 8.0 0.2 3.3 4 0 0 4 4 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF2075 PF09848.9 CDJ37128.1 - 0.6 9.3 6.1 0.62 9.2 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) YscJ_FliF_C PF08345.11 CDJ37128.1 - 0.7 10.2 6.7 40 4.5 0.0 3.1 3 0 0 3 3 3 0 Flagellar M-ring protein C-terminal NB-ARC PF00931.22 CDJ37128.1 - 0.9 8.7 7.1 5 6.2 0.1 2.8 3 0 0 3 3 2 0 NB-ARC domain Vps51 PF08700.11 CDJ37129.1 - 3.4e-16 59.1 0.0 3.4e-16 59.1 0.0 2.3 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 CDJ37129.1 - 4.3e-07 30.1 2.2 1e-06 28.8 1.1 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Dor1 PF04124.12 CDJ37129.1 - 1.5e-05 23.8 0.6 2.6e-05 23.1 0.6 1.3 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 CDJ37129.1 - 0.15 11.8 0.3 0.4 10.5 0.0 1.8 2 0 0 2 2 2 0 Exocyst complex component Sec5 RLL PF10036.9 CDJ37129.1 - 0.52 10.1 7.3 0.045 13.6 1.6 2.1 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein SAPIS-gp6 PF16722.5 CDJ37129.1 - 1.9 8.9 4.8 5.9 7.4 4.8 1.8 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus Glyco_hydro_3_C PF01915.22 CDJ37130.1 - 0.048 13.6 4.0 0.017 15.1 1.4 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain PUF PF00806.19 CDJ37130.1 - 0.059 13.1 0.1 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Pkinase PF00069.25 CDJ37131.1 - 3.4e-40 138.1 0.0 2.8e-26 92.5 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37131.1 - 5.5e-22 78.3 0.0 3.5e-15 56.0 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 CDJ37132.1 - 2.2e-64 217.4 0.0 4e-64 216.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37132.1 - 9.3e-36 123.4 0.0 2.3e-35 122.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ37132.1 - 0.00021 20.7 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Death PF00531.22 CDJ37132.1 - 0.13 12.4 0.6 0.32 11.2 0.6 1.6 1 0 0 1 1 1 0 Death domain adh_short PF00106.25 CDJ37133.1 - 1.1e-31 109.8 0.0 7.5e-28 97.3 0.0 2.5 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ37133.1 - 1.7e-19 70.4 1.2 2.6e-19 69.7 0.1 1.9 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ37133.1 - 1.1e-07 32.0 0.0 1.9e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF4614 PF15391.6 CDJ37133.1 - 0.0091 16.0 1.1 0.014 15.4 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4614) SR-25 PF10500.9 CDJ37133.1 - 0.052 13.2 10.2 0.07 12.7 10.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Polysacc_synt_2 PF02719.15 CDJ37133.1 - 0.072 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DDHD PF02862.17 CDJ37133.1 - 0.18 11.9 1.7 0.26 11.4 1.7 1.2 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 CDJ37133.1 - 1.1 7.9 4.3 1.5 7.5 4.3 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CDJ37133.1 - 1.2 7.9 6.8 1.5 7.6 6.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NPR3 PF03666.13 CDJ37133.1 - 6.6 5.4 7.6 8.5 5.0 7.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 IMCp PF12314.8 CDJ37134.1 - 4.4e-12 46.1 49.7 9.3e-09 35.5 27.5 3.3 1 1 2 3 3 3 3 Inner membrane complex protein ANAPC_CDC26 PF10471.9 CDJ37134.1 - 0.00082 20.2 17.4 0.024 15.5 8.5 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex APC subunit CDC26 DUF2722 PF10846.8 CDJ37134.1 - 0.00095 18.2 11.0 0.036 13.0 9.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ37134.1 - 0.0062 16.6 0.1 0.0062 16.6 0.1 3.8 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ37134.1 - 0.011 15.8 5.9 0.011 15.8 5.9 2.4 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ37134.1 - 0.72 9.4 26.1 0.46 10.0 13.5 2.3 2 0 0 2 2 2 0 Spt20 family GREB1 PF15782.5 CDJ37134.1 - 1 6.4 3.4 1.4 6.0 3.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ37134.1 - 6.4 6.2 11.6 0.47 10.0 5.8 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Inositol_P PF00459.25 CDJ37135.1 - 6.2e-21 75.1 0.1 7.8e-21 74.8 0.1 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family GrpB PF04229.14 CDJ37135.1 - 0.17 12.0 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 GrpB protein DUF3074 PF11274.8 CDJ37137.1 - 0.062 13.3 3.2 0.18 11.8 3.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) Apt1 PF10351.9 CDJ37137.1 - 0.076 11.9 11.4 0.02 13.8 1.7 2.5 1 1 0 2 2 2 0 Golgi-body localisation protein domain Tim54 PF11711.8 CDJ37137.1 - 0.083 11.7 1.7 2.7 6.7 0.1 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 TMEM154 PF15102.6 CDJ37137.1 - 1.6 8.6 0.0 1.6 8.6 0.0 3.2 2 1 0 2 2 2 0 TMEM154 protein family SPX PF03105.19 CDJ37137.1 - 4.3 7.2 24.2 2e+02 1.7 24.2 2.1 1 1 0 1 1 1 0 SPX domain CIAPIN1 PF05093.13 CDJ37137.1 - 4.3 7.9 7.5 0.3 11.6 0.5 2.3 2 1 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis CagX PF03524.15 CDJ37137.1 - 7 6.3 9.7 0.69 9.6 0.4 2.2 2 0 0 2 2 2 0 Conjugal transfer protein TagF_N PF09867.9 CDJ37137.1 - 9 6.3 11.9 0.17 11.9 0.4 2.8 1 1 1 2 2 2 0 TagF N-terminal domain, Type VI secretion system-associated TraT PF05818.12 CDJ37137.1 - 9.9 5.8 18.7 1.2 8.8 8.8 2.4 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein MTBP_C PF14920.6 CDJ37138.1 - 0.00095 19.0 5.5 0.0013 18.6 5.5 1.2 1 0 0 1 1 1 1 MDM2-binding TFIIA PF03153.13 CDJ37138.1 - 0.0061 16.6 17.9 0.0076 16.3 17.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ribosomal_L24 PF17136.4 CDJ37138.1 - 0.0086 16.4 0.0 0.0086 16.4 0.0 2.3 3 0 0 3 3 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 Fer4_18 PF13746.6 CDJ37138.1 - 0.0098 16.1 7.7 0.15 12.3 3.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Sin_N PF04801.13 CDJ37138.1 - 0.028 13.6 13.4 0.031 13.5 13.4 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region DUF908 PF06012.12 CDJ37138.1 - 0.038 13.4 8.0 0.048 13.1 8.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DDHD PF02862.17 CDJ37138.1 - 0.041 14.0 2.6 0.054 13.6 2.6 1.3 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 CDJ37138.1 - 0.24 11.2 8.2 0.3 10.9 8.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 CDJ37138.1 - 0.25 11.3 12.0 0.32 10.9 12.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CCDC53 PF10152.9 CDJ37138.1 - 0.25 11.7 8.7 0.37 11.2 8.7 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Ndc1_Nup PF09531.10 CDJ37138.1 - 0.34 9.6 5.5 0.33 9.6 5.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sec16 PF12932.7 CDJ37138.1 - 0.5 11.0 4.6 0.72 10.5 4.6 1.2 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region CAF1 PF04857.20 CDJ37138.1 - 0.77 8.9 7.2 0.96 8.6 7.2 1.0 1 0 0 1 1 1 0 CAF1 family ribonuclease Neur_chan_memb PF02932.16 CDJ37138.1 - 0.78 9.8 5.1 0.97 9.4 5.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 CDJ37138.1 - 0.98 8.7 10.3 1.2 8.4 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SLC12 PF03522.15 CDJ37138.1 - 1.2 8.1 8.6 1.4 7.9 8.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Activator_LAG-3 PF11498.8 CDJ37138.1 - 1.3 7.9 32.0 1.7 7.5 32.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RNA_pol_Rbc25 PF08292.12 CDJ37138.1 - 1.7 8.9 5.7 5 7.4 2.1 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Presenilin PF01080.17 CDJ37138.1 - 1.8 7.2 12.0 2.3 6.9 12.0 1.1 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 CDJ37138.1 - 3.1 7.3 15.5 4 6.9 15.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hid1 PF12722.7 CDJ37138.1 - 5.4 5.0 9.1 6.6 4.7 9.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein VIT1 PF01988.19 CDJ37138.1 - 5.5 6.8 4.5 8.2 6.2 4.5 1.2 1 0 0 1 1 1 0 VIT family Otopetrin PF03189.13 CDJ37138.1 - 8.9 5.0 6.3 11 4.6 6.3 1.1 1 0 0 1 1 1 0 Otopetrin AAA_23 PF13476.6 CDJ37138.1 - 9.6 6.6 13.0 13 6.2 13.0 1.1 1 0 0 1 1 1 0 AAA domain A_deaminase PF00962.22 CDJ37139.1 - 3.9e-91 305.8 0.0 5.3e-91 305.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Herpes_UL52 PF03121.15 CDJ37142.1 - 3.5e-11 42.9 0.0 1e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Pyrophosphatase PF00719.19 CDJ37143.1 - 2.5e-10 40.4 0.0 3.2e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 Inorganic pyrophosphatase DDHD PF02862.17 CDJ37143.1 - 0.0055 16.9 0.0 0.018 15.2 0.0 1.7 2 0 0 2 2 2 1 DDHD domain RNA_pol_Rpc4 PF05132.14 CDJ37143.1 - 0.036 14.5 0.0 0.036 14.5 0.0 2.0 3 0 0 3 3 3 0 RNA polymerase III RPC4 Suf PF05843.14 CDJ37143.1 - 0.25 11.3 2.9 0.39 10.7 2.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2057 PF09829.9 CDJ37143.1 - 2 8.5 17.2 0.092 12.9 0.3 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2057) Presenilin PF01080.17 CDJ37143.1 - 2.4 6.9 4.8 4 6.1 4.8 1.3 1 0 0 1 1 1 0 Presenilin RIFIN PF02009.16 CDJ37143.1 - 3.4 7.5 10.0 0.14 12.0 3.1 1.8 2 0 0 2 2 2 0 Rifin GATA PF00320.27 CDJ37144.1 - 4e-08 32.7 3.5 1.1e-07 31.3 3.5 1.8 1 0 0 1 1 1 1 GATA zinc finger DUF4179 PF13786.6 CDJ37144.1 - 0.28 11.7 13.5 3.4 8.2 0.2 4.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) Maf PF02545.14 CDJ37145.1 - 2.3e-32 112.1 0.9 2.8e-22 79.3 0.2 2.9 2 1 0 2 2 2 2 Maf-like protein Hydrolase_6 PF13344.6 CDJ37145.1 - 0.059 13.5 0.0 0.38 10.9 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF2072 PF09845.9 CDJ37145.1 - 2.1 8.6 5.6 0.95 9.7 2.3 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein Init_tRNA_PT PF04179.12 CDJ37145.1 - 9.2 6.6 10.1 6.4 7.1 0.2 3.3 3 1 0 3 3 3 0 Rit1 DUSP-like domain PAC3 PF10178.9 CDJ37146.1 - 0.00029 20.9 0.0 0.00042 20.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 DUF1180 PF06679.12 CDJ37146.1 - 0.8 10.1 5.2 1.2 9.5 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Macoilin PF09726.9 CDJ37147.1 - 5.7 5.4 11.2 3.3 6.2 7.0 2.1 2 0 0 2 2 2 0 Macoilin family TMEM65 PF10507.9 CDJ37148.1 - 1.8e-39 134.0 0.1 1.8e-39 134.0 0.1 2.5 2 0 0 2 2 2 1 Transmembrane protein 65 GAF PF01590.26 CDJ37148.1 - 6.9e-06 26.7 0.1 0.0014 19.2 0.1 3.1 1 1 0 1 1 1 1 GAF domain TMEM117 PF15113.6 CDJ37148.1 - 0.034 13.1 1.2 0.052 12.5 1.2 1.1 1 0 0 1 1 1 0 TMEM117 protein family UPF0016 PF01169.19 CDJ37148.1 - 0.089 13.1 2.0 0.26 11.6 1.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 Golgin_A5 PF09787.9 CDJ37148.1 - 1.3 8.4 17.6 2.5 7.5 17.6 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Peroxin-3 PF04882.12 CDJ37149.1 - 0.00035 19.7 21.4 0.0024 16.9 0.0 3.3 2 1 1 4 4 4 2 Peroxin-3 NDUF_B12 PF08122.12 CDJ37149.1 - 0.022 14.8 0.8 7.3 6.7 0.0 3.8 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Dpy19 PF10034.9 CDJ37149.1 - 0.11 10.7 3.6 0.18 10.0 3.6 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation 7tm_1 PF00001.21 CDJ37149.1 - 0.26 10.6 1.2 0.45 9.8 1.2 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) MBR1 PF17058.5 CDJ37149.1 - 0.72 10.1 3.8 1.5 9.1 3.8 1.6 1 1 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 tRNA-synt_2 PF00152.20 CDJ37151.1 - 1.8e-82 276.9 0.0 2.3e-82 276.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ37151.1 - 5.8e-10 39.0 0.1 1.8e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDJ37151.1 - 0.00036 20.1 0.1 0.0029 17.1 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) BAF1_ABF1 PF04684.13 CDJ37152.1 - 3.7 6.5 7.9 5.2 6.0 7.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DNA_pol3_tau_4 PF12168.8 CDJ37152.1 - 4.2 8.0 13.3 0.78 10.3 9.5 1.9 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Presenilin PF01080.17 CDJ37152.1 - 5.1 5.7 5.1 6.5 5.4 5.1 1.2 1 0 0 1 1 1 0 Presenilin DUF2785 PF10978.8 CDJ37153.1 - 7.5 6.3 7.1 0.47 10.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) DUF2362 PF10154.9 CDJ37154.1 - 3.5e-06 26.3 0.0 3.5e-06 26.3 0.0 3.6 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2362) Ank_4 PF13637.6 CDJ37155.1 - 1.5e-05 25.4 0.0 0.00063 20.3 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ37155.1 - 7.3e-05 22.9 0.5 0.11 13.1 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 CDJ37155.1 - 0.00026 21.5 1.3 0.00097 19.7 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ37155.1 - 0.017 15.5 0.1 0.081 13.3 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) START PF01852.19 CDJ37155.1 - 0.036 13.5 0.4 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 START domain AviRa PF11599.8 CDJ37155.1 - 0.15 11.5 0.6 0.28 10.6 0.6 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Ank PF00023.30 CDJ37155.1 - 0.52 10.9 0.1 0.52 10.9 0.1 4.4 5 1 0 5 5 5 0 Ankyrin repeat DENN PF02141.21 CDJ37157.1 - 9.1e-24 84.4 10.2 5.1e-20 72.2 7.1 2.7 2 0 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 CDJ37157.1 - 8.1e-06 26.5 2.4 0.0011 19.6 0.3 3.3 2 0 0 2 2 2 2 uDENN domain PsiB PF06290.11 CDJ37158.1 - 0.076 12.5 0.0 15 5.1 0.0 3.0 2 0 0 2 2 2 0 Plasmid SOS inhibition protein (PsiB) Peptidase_S46 PF10459.9 CDJ37158.1 - 0.27 9.8 3.6 0.19 10.4 1.1 1.8 2 0 0 2 2 2 0 Peptidase S46 zf-CpG_bind_C PF12269.8 CDJ37158.1 - 0.47 10.2 3.8 10 5.8 1.8 2.8 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain RRM_1 PF00076.22 CDJ37159.1 - 9.9e-16 57.3 0.1 1.5e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 CDJ37159.1 - 7.3e-11 42.2 0.0 3.3e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 SPOC domain RRM_occluded PF16842.5 CDJ37159.1 - 0.033 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif SET_assoc PF11767.8 CDJ37159.1 - 0.051 13.2 0.2 0.089 12.4 0.2 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_3 PF08777.11 CDJ37159.1 - 0.086 12.9 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 RNA binding motif Methyltransf_11 PF08241.12 CDJ37160.1 - 8.8e-15 55.1 0.3 1.4e-12 48.1 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ37160.1 - 4.2e-12 46.6 0.5 2.9e-10 40.7 0.3 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ37160.1 - 2.9e-05 23.9 0.0 2.9e-05 23.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ37160.1 - 0.00014 22.5 3.5 0.00028 21.6 0.0 2.8 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ37160.1 - 0.00026 20.9 1.3 0.00052 19.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CDJ37160.1 - 0.07 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.18 CDJ37160.1 - 0.088 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 CDJ37160.1 - 0.088 12.6 0.0 0.97 9.2 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Spt20 PF12090.8 CDJ37160.1 - 1.3 8.6 15.5 1.9 8.1 15.5 1.1 1 0 0 1 1 1 0 Spt20 family zf-DNL PF05180.12 CDJ37162.1 - 1e-27 95.8 0.4 1.4e-27 95.4 0.4 1.2 1 0 0 1 1 1 1 DNL zinc finger DUF3458_C PF17432.2 CDJ37163.1 - 2.3e-100 336.1 5.5 4e-100 335.3 5.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 CDJ37163.1 - 2.8e-48 164.4 0.2 4.8e-48 163.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 CDJ37163.1 - 7e-23 80.9 0.1 1.5e-22 79.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 CDJ37163.1 - 1e-11 45.3 0.0 1.9e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 CDJ37163.1 - 0.055 13.9 0.1 0.34 11.3 0.1 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase cNMP_binding PF00027.29 CDJ37165.1 - 6e-22 77.5 0.0 8.1e-11 41.8 0.0 3.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Spc7 PF08317.11 CDJ37165.1 - 0.35 9.7 26.3 0.01 14.7 19.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Bacillus_HBL PF05791.11 CDJ37165.1 - 2.7 7.8 10.3 3.5 7.4 4.4 2.7 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) V_ATPase_I PF01496.19 CDJ37165.1 - 2.8 5.7 5.9 6.2 4.6 5.9 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 CDJ37165.1 - 4.5 6.4 13.2 0.47 9.7 1.5 2.6 1 1 1 2 2 2 0 TMPIT-like protein ClpS PF02617.17 CDJ37166.1 - 1.3e-11 44.1 0.1 2e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Pterin_bind PF00809.22 CDJ37167.1 - 1.5e-73 247.5 0.1 2.2e-73 246.9 0.1 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 CDJ37167.1 - 1e-24 87.2 0.1 3.6e-24 85.4 0.0 2.0 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF3560 PF12083.8 CDJ37167.1 - 0.18 11.9 2.4 1.3 9.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3560) CAP PF00188.26 CDJ37168.1 - 0.017 15.9 1.3 0.026 15.4 1.3 1.5 1 1 0 1 1 1 0 Cysteine-rich secretory protein family DUF1877 PF08974.10 CDJ37168.1 - 0.12 12.4 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) CAP PF00188.26 CDJ37169.1 - 0.0052 17.6 0.2 0.0084 16.9 0.2 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ37170.1 - 0.016 16.0 1.3 0.027 15.3 1.3 1.4 1 1 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ37171.1 - 0.0093 16.8 0.6 0.015 16.2 0.6 1.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ37172.1 - 0.0079 17.0 2.8 0.016 16.0 2.8 1.6 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ37173.1 - 0.17 12.7 0.7 0.46 11.3 1.2 1.7 2 1 0 2 2 2 0 Cysteine-rich secretory protein family Glyco_transf_7N PF13733.6 CDJ37173.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 CAP PF00188.26 CDJ37174.1 - 0.006 17.4 0.1 0.0082 17.0 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TcpA PF05946.12 CDJ37176.1 - 0.054 13.6 0.7 0.2 11.8 0.6 1.8 1 1 1 2 2 2 0 Toxin-coregulated pilus subunit TcpA CAP PF00188.26 CDJ37178.1 - 0.067 14.0 0.0 0.097 13.5 0.0 1.3 1 0 0 1 1 1 0 Cysteine-rich secretory protein family tRNA-synt_1 PF00133.22 CDJ37179.1 - 4.7e-30 104.4 0.0 1.4e-06 26.9 0.0 4.8 4 1 0 4 4 4 4 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ37179.1 - 4.3e-16 59.2 0.0 1.6e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ37179.1 - 2.2e-14 53.1 0.0 3.3e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CDJ37179.1 - 2.9e-09 36.7 0.0 7.2e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF5400 PF17379.2 CDJ37180.1 - 0.039 14.4 2.8 0.068 13.6 2.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5400) DUF2070 PF09843.9 CDJ37180.1 - 1.8 6.7 5.8 2.8 6.1 5.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3169 PF11368.8 CDJ37180.1 - 3.6 7.0 5.3 1.2 8.6 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) Tetraspanin PF00335.20 CDJ37180.1 - 3.9 7.1 8.2 7.3 6.2 8.1 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF2207 PF09972.9 CDJ37180.1 - 5.1 5.7 4.6 8.6 5.0 2.6 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) FKBP_C PF00254.28 CDJ37181.1 - 1e-18 67.5 0.0 1.9e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Med15 PF09606.10 CDJ37181.1 - 0.34 9.5 34.2 0.089 11.5 4.1 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ndc1_Nup PF09531.10 CDJ37181.1 - 3.9 6.1 12.1 1.4 7.5 6.8 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Activator_LAG-3 PF11498.8 CDJ37181.1 - 9.4 5.1 53.6 1.9 7.4 29.7 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 RAP PF08373.10 CDJ37182.1 - 6.5e-22 77.4 0.2 6.5e-22 77.4 0.2 3.2 2 0 0 2 2 2 1 RAP domain tRNA-synt_1d PF00750.19 CDJ37183.1 - 1.4e-20 73.6 1.7 7.2e-14 51.5 0.0 3.8 4 1 0 4 4 4 2 tRNA synthetases class I (R) DALR_1 PF05746.15 CDJ37183.1 - 7.5e-11 42.2 0.0 7.5e-11 42.2 0.0 4.3 4 1 0 4 4 4 1 DALR anticodon binding domain SUIM_assoc PF16619.5 CDJ37183.1 - 3e-05 24.0 0.0 0.00077 19.5 0.2 12.9 7 4 1 8 8 8 3 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ37183.1 - 0.00076 19.2 7.8 0.00076 19.2 7.8 7.2 6 2 0 6 6 6 2 Nuclear RNA-splicing-associated protein DUF3336 PF11815.8 CDJ37186.1 - 4.2e-14 52.4 0.0 7.2e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CDJ37186.1 - 1.9e-12 47.8 0.5 9e-09 35.8 0.2 3.4 2 2 2 4 4 4 2 Patatin-like phospholipase LEP503 PF15221.6 CDJ37186.1 - 0.01 16.1 0.0 0.04 14.2 0.0 2.0 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 CCT_2 PF09425.10 CDJ37186.1 - 2.1 8.3 4.9 1.4 8.9 1.0 2.6 2 0 0 2 2 2 0 Divergent CCT motif Ribosomal_L2_C PF03947.18 CDJ37188.1 - 7e-18 65.0 0.0 2.4e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CDJ37188.1 - 1.6e-08 34.4 0.0 2.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MORN PF02493.20 CDJ37190.1 - 3.3e-42 139.9 62.6 4.2e-06 26.3 0.8 9.9 10 0 0 10 10 10 9 MORN repeat Mito_carr PF00153.27 CDJ37192.1 - 6.8e-47 157.3 1.7 1.5e-15 56.9 0.0 4.1 3 2 0 3 3 3 3 Mitochondrial carrier protein PepSY_TM PF03929.16 CDJ37193.1 - 6.3 6.4 12.1 98 2.5 12.1 2.2 1 1 0 1 1 1 0 PepSY-associated TM region DUF747 PF05346.11 CDJ37194.1 - 7e-114 380.6 1.7 1.4e-113 379.5 1.7 1.6 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF4834 PF16118.5 CDJ37194.1 - 0.006 17.5 8.5 0.006 17.5 8.5 10.6 11 2 0 11 11 11 2 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ37194.1 - 0.047 12.6 0.1 0.047 12.6 0.1 13.9 9 5 1 11 11 11 0 Protein of unknown function (DUF2722) PRIMA1 PF16101.5 CDJ37194.1 - 0.25 11.4 5.4 0.65 10.0 1.0 3.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 GTP_EFTU PF00009.27 CDJ37195.1 - 2.8e-32 111.8 4.6 4.1e-32 111.3 0.1 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CDJ37195.1 - 9.6e-16 57.8 0.0 6.3e-11 42.3 0.0 3.4 3 0 0 3 3 3 2 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CDJ37195.1 - 1.1e-07 31.9 0.0 2.6e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CDJ37195.1 - 0.00049 20.3 0.1 0.0021 18.3 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CDJ37195.1 - 0.00079 19.4 0.0 1.1 9.1 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 CDJ37195.1 - 0.0076 16.3 3.4 0.33 11.0 0.1 3.5 2 1 0 3 3 3 1 Dynamin family SRPRB PF09439.10 CDJ37195.1 - 0.012 15.1 0.0 0.03 13.8 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 CDJ37195.1 - 0.017 14.9 0.1 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 CDJ37195.1 - 0.031 13.9 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 Ras family IF2_N PF04760.15 CDJ37195.1 - 0.14 12.0 0.0 0.78 9.6 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region DUF4205 PF13898.6 CDJ37195.1 - 0.95 8.3 5.9 3.9 6.3 5.9 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) Ribosomal_L21p PF00829.21 CDJ37197.1 - 6.4e-20 71.3 0.0 8.4e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein TFIIA PF03153.13 CDJ37198.1 - 2.2 8.2 14.3 3.6 7.5 14.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_2 PF12796.7 CDJ37199.1 - 9.4e-08 32.5 0.7 0.015 15.9 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ37199.1 - 1.3e-06 28.9 0.4 2 9.1 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ37199.1 - 1.5e-06 28.0 0.9 9.6 7.2 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CDJ37199.1 - 0.019 15.2 2.4 20 5.7 0.1 3.8 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ribosomal_L38e PF01781.18 CDJ37200.1 - 5.1e-28 97.0 0.4 6e-28 96.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Succ_CoA_lig PF13607.6 CDJ37200.1 - 0.13 12.0 0.6 0.19 11.5 0.6 1.2 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain SRR1 PF07985.12 CDJ37201.1 - 1.1e-13 51.0 0.5 2.1e-13 50.1 0.5 1.6 1 0 0 1 1 1 1 SRR1 TFIIA PF03153.13 CDJ37201.1 - 6.3 6.7 10.8 0.85 9.6 1.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Collagen PF01391.18 CDJ37202.1 - 0.0038 16.9 18.4 0.0038 16.9 18.4 2.5 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) DUF4256 PF14066.6 CDJ37202.1 - 0.059 13.0 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) TraD_N PF12615.8 CDJ37202.1 - 3.1 8.6 5.3 2.6 8.9 1.4 2.8 2 1 1 3 3 3 0 F sex factor protein N terminal zf-ZPR1 PF03367.13 CDJ37204.1 - 4.5e-94 312.6 0.0 3.8e-49 166.6 0.0 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Zn_Tnp_IS1595 PF12760.7 CDJ37204.1 - 0.00038 20.4 17.3 0.0025 17.7 0.9 4.3 3 1 1 4 4 4 2 Transposase zinc-ribbon domain HypA PF01155.19 CDJ37204.1 - 0.0092 16.0 7.7 0.28 11.2 2.1 2.6 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Eapp_C PF10238.9 CDJ37204.1 - 0.43 10.7 2.6 14 5.7 0.7 2.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein Zn-ribbon_8 PF09723.10 CDJ37204.1 - 4.5 7.5 13.2 10 6.3 0.9 4.3 4 0 0 4 4 4 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 CDJ37204.1 - 5.8 6.9 11.4 4.3 7.3 0.3 3.6 3 1 0 3 3 3 0 Putative transposase DNA-binding domain DUF16 PF01519.16 CDJ37206.1 - 0.16 12.5 0.0 2.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 YjbE PF11106.8 CDJ37206.1 - 5.5 7.3 9.5 0.82 9.9 5.6 1.7 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Kinase-like PF14531.6 CDJ37207.1 - 0.0015 17.9 0.1 0.0015 17.9 0.1 2.5 2 1 0 2 2 2 1 Kinase-like Pkinase PF00069.25 CDJ37207.1 - 0.0073 15.7 0.5 0.02 14.2 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Exo5 PF09810.9 CDJ37208.1 - 4.1e-34 118.7 0.1 4.1e-34 118.7 0.1 5.2 5 1 0 5 5 5 3 Exonuclease V - a 5' deoxyribonuclease FAD_binding_2 PF00890.24 CDJ37209.1 - 1.6e-116 389.9 5.2 2.3e-116 389.3 5.2 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CDJ37209.1 - 1.2e-41 141.7 1.2 1.9e-41 141.1 1.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 CDJ37209.1 - 0.00026 20.3 1.0 0.018 14.3 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 CDJ37209.1 - 0.00062 19.1 0.3 0.0017 17.7 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDJ37209.1 - 0.0021 17.7 0.8 0.0045 16.6 0.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CDJ37209.1 - 0.0045 16.3 0.3 0.0085 15.4 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CDJ37209.1 - 0.017 14.3 5.9 0.023 13.8 1.6 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CDJ37209.1 - 0.019 14.0 0.1 0.18 10.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 CDJ37209.1 - 1.9 7.1 5.4 0.21 10.2 0.6 1.8 3 0 0 3 3 3 0 HI0933-like protein DEAD PF00270.29 CDJ37210.1 - 2.8e-29 102.1 0.5 5.9e-21 75.0 0.0 3.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ37210.1 - 6.1e-16 58.8 2.7 6.8e-16 58.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Cwf_Cwc_15 PF04889.12 CDJ37210.1 - 0.0037 17.0 2.2 0.0037 17.0 2.2 6.6 6 1 1 7 7 7 1 Cwf15/Cwc15 cell cycle control protein RRM_1 PF00076.22 CDJ37211.1 - 1.2e-34 117.9 0.0 4.9e-14 51.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ37211.1 - 1.8e-05 24.3 0.0 0.96 9.0 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CDJ37211.1 - 0.015 15.3 0.0 8.1 6.6 0.0 3.2 3 0 0 3 3 3 0 Limkain b1 TFIIA PF03153.13 CDJ37211.1 - 0.053 13.5 23.7 0.17 11.8 8.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ37211.1 - 0.2 10.6 12.5 0.28 10.1 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF702 PF05142.12 CDJ37211.1 - 0.78 10.2 9.6 2.9 8.3 4.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Spt20 PF12090.8 CDJ37211.1 - 2 8.0 27.0 4 7.0 8.7 2.2 2 0 0 2 2 2 0 Spt20 family BAT2_N PF07001.11 CDJ37211.1 - 2.2 8.7 12.1 3 8.3 5.2 2.4 2 0 0 2 2 2 0 BAT2 N-terminus DUF2367 PF10164.9 CDJ37211.1 - 3.2 8.3 0.0 3.2 8.3 0.0 3.4 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2367) IPK PF03770.16 CDJ37213.1 - 5.4e-09 36.2 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase RRM_1 PF00076.22 CDJ37214.1 - 7.1e-21 73.8 0.0 2.3e-12 46.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ37214.1 - 2.2e-08 33.9 0.0 0.00065 19.5 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CDJ37214.1 - 8.5e-07 28.6 0.0 0.05 13.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 CDJ37214.1 - 0.014 15.2 0.0 0.054 13.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 CDJ37214.1 - 0.064 13.3 0.3 9.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TFIIA PF03153.13 CDJ37214.1 - 0.48 10.4 7.1 0.58 10.1 7.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ37214.1 - 0.49 10.3 2.3 0.77 9.7 2.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Gly-zipper_YMGG PF13441.6 CDJ37214.1 - 2.6 7.9 23.3 4.9 7.0 0.2 4.1 2 1 1 3 3 3 0 YMGG-like Gly-zipper E7 PF00527.18 CDJ37215.1 - 0.52 10.5 2.9 8.2 6.7 0.1 2.2 1 1 1 2 2 2 0 E7 protein, Early protein FAD_binding_3 PF01494.19 CDJ37216.1 - 0.027 13.7 1.2 0.036 13.3 1.2 1.1 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 CDJ37216.1 - 0.034 14.4 0.4 0.034 14.4 0.4 3.0 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Rotamase_2 PF13145.6 CDJ37216.1 - 0.54 11.1 7.2 0.74 10.7 2.1 2.2 2 0 0 2 2 2 0 PPIC-type PPIASE domain 2-Hacid_dh_C PF02826.19 CDJ37217.1 - 5.5e-46 156.2 0.0 7.4e-46 155.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CDJ37217.1 - 0.00081 19.9 0.1 0.0026 18.3 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 CDJ37217.1 - 0.0012 19.0 0.1 0.002 18.2 0.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 CDJ37217.1 - 0.0021 18.2 0.0 0.0035 17.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 CDJ37217.1 - 0.066 13.7 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Wzz PF02706.15 CDJ37218.1 - 0.029 14.6 0.1 0.07 13.4 0.1 1.6 1 0 0 1 1 1 0 Chain length determinant protein FAM176 PF14851.6 CDJ37219.1 - 0.00027 20.6 3.4 0.00031 20.4 3.4 1.0 1 0 0 1 1 1 1 FAM176 family DUF4834 PF16118.5 CDJ37219.1 - 0.0016 19.4 1.9 0.0019 19.1 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Ctr PF04145.15 CDJ37219.1 - 0.0027 18.3 1.9 0.0032 18.1 1.9 1.0 1 0 0 1 1 1 1 Ctr copper transporter family XK-related PF09815.9 CDJ37219.1 - 0.0059 15.7 1.5 0.0065 15.6 1.5 1.1 1 0 0 1 1 1 1 XK-related protein V_ATPase_I PF01496.19 CDJ37219.1 - 0.0066 14.4 5.8 0.0076 14.2 5.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SID-1_RNA_chan PF13965.6 CDJ37219.1 - 0.0097 14.4 0.3 0.01 14.3 0.3 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Connexin PF00029.19 CDJ37219.1 - 0.017 14.9 3.8 0.019 14.7 3.8 1.1 1 0 0 1 1 1 0 Connexin SLD3 PF08639.10 CDJ37219.1 - 0.019 13.8 8.7 0.019 13.7 8.7 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 Presenilin PF01080.17 CDJ37219.1 - 0.023 13.5 4.4 0.023 13.5 4.4 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ37219.1 - 0.025 14.2 13.6 0.028 14.0 13.6 1.2 1 0 0 1 1 1 0 Spt20 family TRAP_alpha PF03896.16 CDJ37219.1 - 0.04 13.1 2.0 0.043 13.0 2.0 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PepSY_TM_like_2 PF16357.5 CDJ37219.1 - 0.043 13.8 0.9 0.051 13.6 0.9 1.1 1 0 0 1 1 1 0 Putative PepSY_TM-like DNApol_Exo PF18136.1 CDJ37219.1 - 0.051 12.7 8.7 0.056 12.6 8.7 1.0 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Ureide_permease PF07168.11 CDJ37219.1 - 0.051 12.3 1.6 0.052 12.3 1.6 1.0 1 0 0 1 1 1 0 Ureide permease PIP5K PF01504.18 CDJ37219.1 - 0.06 12.6 3.3 0.061 12.5 3.3 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CCDC53 PF10152.9 CDJ37219.1 - 0.066 13.6 6.8 0.075 13.4 6.8 1.0 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Jak1_Phl PF17887.1 CDJ37219.1 - 0.071 13.1 6.7 0.084 12.8 6.7 1.1 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain DUF2828 PF11443.8 CDJ37219.1 - 0.079 11.0 7.2 0.082 11.0 7.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RPA43_OB PF17875.1 CDJ37219.1 - 0.08 13.6 3.3 0.091 13.4 3.3 1.1 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Zip PF02535.22 CDJ37219.1 - 0.082 12.1 0.6 0.077 12.2 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter O-antigen_lig PF13425.6 CDJ37219.1 - 0.093 11.5 0.6 0.1 11.4 0.6 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein UPF0239 PF06783.11 CDJ37219.1 - 0.13 12.5 6.1 0.17 12.1 6.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Scs3p PF10261.9 CDJ37219.1 - 0.13 11.7 1.3 0.14 11.6 1.3 1.0 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM CBP_BcsG PF11658.8 CDJ37219.1 - 0.14 10.5 3.6 0.15 10.4 3.6 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Serinc PF03348.15 CDJ37219.1 - 0.15 10.9 2.4 0.17 10.8 2.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1980 PF09323.10 CDJ37219.1 - 0.15 11.9 1.3 0.17 11.8 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Peroxin-13_N PF04088.13 CDJ37219.1 - 0.16 12.3 1.8 0.17 12.2 1.8 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Otopetrin PF03189.13 CDJ37219.1 - 0.18 10.6 1.7 0.19 10.5 1.7 1.0 1 0 0 1 1 1 0 Otopetrin CLN3 PF02487.17 CDJ37219.1 - 0.19 10.7 3.0 0.2 10.7 3.0 1.0 1 0 0 1 1 1 0 CLN3 protein Kei1 PF08552.11 CDJ37219.1 - 0.22 11.4 3.1 0.22 11.4 3.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF808 PF05661.12 CDJ37219.1 - 0.25 10.3 2.0 0.3 10.1 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Dpy19 PF10034.9 CDJ37219.1 - 0.28 9.4 1.1 0.31 9.2 1.1 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation CPSF100_C PF13299.6 CDJ37219.1 - 0.28 11.3 7.5 0.31 11.2 7.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal OATP PF03137.20 CDJ37219.1 - 0.29 9.4 1.7 0.28 9.4 1.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Nucleoside_tran PF01733.18 CDJ37219.1 - 0.31 10.4 1.4 0.34 10.3 1.4 1.0 1 0 0 1 1 1 0 Nucleoside transporter DUF775 PF05603.12 CDJ37219.1 - 0.31 10.5 9.9 0.35 10.4 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) EMC3_TMCO1 PF01956.16 CDJ37219.1 - 0.32 10.7 9.7 0.33 10.7 9.7 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like SpoIIP PF07454.11 CDJ37219.1 - 0.33 10.4 10.1 0.36 10.2 10.1 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TIMELESS PF04821.14 CDJ37219.1 - 0.4 9.9 8.4 0.48 9.6 8.4 1.0 1 0 0 1 1 1 0 Timeless protein Folliculin PF11704.8 CDJ37219.1 - 0.47 10.3 5.5 0.52 10.2 5.5 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Borrelia_P83 PF05262.11 CDJ37219.1 - 0.48 8.8 17.9 0.51 8.8 17.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Folate_carrier PF01770.18 CDJ37219.1 - 0.55 8.9 2.1 0.54 8.9 2.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier CSG2 PF16965.5 CDJ37219.1 - 0.63 8.9 1.5 0.64 8.9 1.5 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Ndc1_Nup PF09531.10 CDJ37219.1 - 0.67 8.6 7.3 0.82 8.3 7.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GNAT_acetyltr_2 PF13718.6 CDJ37219.1 - 0.74 9.2 7.5 0.86 9.0 7.5 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 PigN PF04987.14 CDJ37219.1 - 0.75 8.6 2.1 0.72 8.7 2.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) EOS1 PF12326.8 CDJ37219.1 - 0.76 9.7 2.4 0.83 9.6 2.4 1.2 1 0 0 1 1 1 0 N-glycosylation protein Eapp_C PF10238.9 CDJ37219.1 - 0.88 9.6 10.6 1 9.5 10.6 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein EIIBC-GUT_N PF03612.14 CDJ37219.1 - 0.89 9.3 9.9 1 9.1 9.9 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Coilin_N PF15862.5 CDJ37219.1 - 1 9.2 12.7 1.2 9.0 12.7 1.1 1 0 0 1 1 1 0 Coilin N-terminus DDHD PF02862.17 CDJ37219.1 - 1.4 9.0 7.4 1.5 9.0 7.4 1.0 1 0 0 1 1 1 0 DDHD domain DUF3408 PF11888.8 CDJ37219.1 - 1.6 8.9 12.9 1.8 8.7 12.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) FemAB PF02388.16 CDJ37219.1 - 1.7 7.4 12.0 1.9 7.3 12.0 1.0 1 0 0 1 1 1 0 FemAB family ATP-synt_E PF05680.12 CDJ37219.1 - 2.8 8.3 13.7 3.2 8.2 13.7 1.1 1 0 0 1 1 1 0 ATP synthase E chain DUF3987 PF13148.6 CDJ37219.1 - 3.1 6.7 13.0 3.4 6.6 13.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) MMR1 PF08505.10 CDJ37219.1 - 3.5 7.8 13.1 3.8 7.7 13.1 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein ORC_WH_C PF18137.1 CDJ37219.1 - 5 7.2 12.5 5.5 7.1 12.5 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Neur_chan_memb PF02932.16 CDJ37219.1 - 5.7 6.9 6.3 6.3 6.8 6.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ37219.1 - 6.5 6.5 14.7 7.5 6.3 14.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2722 PF10846.8 CDJ37219.1 - 7 5.5 17.1 7.8 5.3 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) OAD_gamma PF04277.13 CDJ37219.1 - 7.2 7.3 7.9 29 5.4 7.9 1.9 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AIF_C PF14721.6 CDJ37219.1 - 8.9 6.7 8.9 10 6.5 8.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term HORMA PF02301.18 CDJ37220.1 - 1.7e-32 112.7 0.0 2.4e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Ribosomal_60s PF00428.19 CDJ37220.1 - 0.0027 18.3 9.3 0.19 12.3 0.8 2.3 2 0 0 2 2 2 2 60s Acidic ribosomal protein CAF1 PF04857.20 CDJ37221.1 - 1.3 8.2 11.4 0.21 10.7 0.2 2.7 2 1 0 2 2 2 0 CAF1 family ribonuclease DUF4710 PF15828.5 CDJ37221.1 - 3.6 7.8 9.3 2.1 8.5 2.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) DUF4820 PF16091.5 CDJ37224.1 - 5.2 6.4 12.4 0.054 12.9 0.8 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4820) RRM_1 PF00076.22 CDJ37225.1 - 1.1e-16 60.4 0.0 1.5e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ37225.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 CDJ37225.1 - 0.098 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNARE PF05739.19 CDJ37226.1 - 3.2e-07 30.2 0.0 5.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CDJ37226.1 - 0.00014 21.6 0.2 0.0003 20.5 0.2 1.5 1 0 0 1 1 1 1 Syntaxin Prominin PF05478.11 CDJ37226.1 - 0.1 10.5 0.3 0.13 10.2 0.3 1.1 1 0 0 1 1 1 0 Prominin TerB PF05099.13 CDJ37226.1 - 0.12 12.3 1.5 0.19 11.7 1.5 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TerB GSP_synth PF03738.14 CDJ37226.1 - 0.19 10.9 0.4 0.26 10.4 0.4 1.1 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp Spt20 PF12090.8 CDJ37227.1 - 0.00044 19.9 12.8 0.00044 19.9 12.8 3.4 3 0 0 3 3 3 2 Spt20 family DUF2722 PF10846.8 CDJ37227.1 - 0.00082 18.4 8.8 0.00082 18.4 8.8 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) DUF455 PF04305.14 CDJ37227.1 - 2.3 7.7 5.9 1.6 8.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF455) Thioredoxin PF00085.20 CDJ37228.1 - 5.7e-39 132.3 0.0 8.6e-22 77.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 CDJ37228.1 - 5.3e-10 39.5 0.0 1.8e-05 24.7 0.0 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CDJ37228.1 - 0.001 19.5 0.0 0.12 12.9 0.0 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDJ37228.1 - 0.01 16.1 0.0 4.2 7.8 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.21 CDJ37228.1 - 0.014 15.4 0.0 0.54 10.2 0.0 2.8 3 0 0 3 3 3 0 AhpC/TSA family ERp29_N PF07912.13 CDJ37228.1 - 0.033 14.3 0.0 7.9 6.7 0.0 3.3 2 1 0 2 2 2 0 ERp29, N-terminal domain Mucin PF01456.17 CDJ37228.1 - 0.16 12.0 0.2 0.29 11.1 0.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RCC1 PF00415.18 CDJ37229.1 - 1.7e-66 220.7 34.9 2.6e-15 56.7 0.8 8.1 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ37229.1 - 2.7e-36 122.6 60.6 7.4e-09 35.2 1.6 8.4 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 CDJ37229.1 - 6.9e-05 22.7 0.3 2.9 7.6 0.0 4.7 5 0 0 5 5 5 2 TUP1-like enhancer of split Kelch_2 PF07646.15 CDJ37229.1 - 0.66 10.1 9.6 25 5.1 0.2 5.5 6 0 0 6 6 6 0 Kelch motif Ribosomal_L5e PF17144.4 CDJ37230.1 - 2.2e-81 271.6 0.4 2.2e-81 271.6 0.4 1.5 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CDJ37230.1 - 2.2e-31 108.6 6.7 2.2e-31 108.6 6.7 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF885 PF05960.11 CDJ37230.1 - 0.081 12.6 2.7 0.11 12.1 2.7 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Dus PF01207.17 CDJ37232.1 - 2.1e-46 158.4 0.1 6.3e-44 150.3 0.1 2.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Alba PF01918.21 CDJ37233.1 - 3.7e-08 33.1 0.0 6.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 CDJ37233.1 - 0.00028 20.8 2.3 0.95 9.4 0.1 3.2 2 1 1 3 3 3 2 Rpp20 subunit of nuclear RNase MRP and P Ribosomal_S7e PF01251.18 CDJ37234.1 - 2.9e-66 222.7 2.6 3.3e-66 222.6 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e FtsQ PF03799.15 CDJ37234.1 - 0.076 13.8 0.8 0.41 11.5 0.1 2.1 1 1 1 2 2 2 0 Cell division protein FtsQ DnaJ PF00226.31 CDJ37235.1 - 0.0062 16.6 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain SF3b10 PF07189.11 CDJ37236.1 - 1.8e-31 108.0 0.0 2.9e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF4820 PF16091.5 CDJ37236.1 - 0.038 13.3 1.9 0.046 13.1 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3391 PF11871.8 CDJ37236.1 - 0.079 13.5 3.6 0.11 13.0 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) FYDLN_acid PF09538.10 CDJ37236.1 - 2 9.2 12.7 2.8 8.7 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TRAP_alpha PF03896.16 CDJ37236.1 - 4.9 6.3 6.6 6.6 5.8 6.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.14 CDJ37236.1 - 5.6 7.4 9.2 7.8 6.9 9.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4539 PF15072.6 CDJ37238.1 - 1.1e-09 38.1 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) DUF3626 PF12294.8 CDJ37238.1 - 0.055 12.5 0.2 0.12 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) Rib_5-P_isom_A PF06026.14 CDJ37239.1 - 8.1e-49 165.5 0.3 1.3e-47 161.6 0.3 2.0 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) BetR PF08667.10 CDJ37239.1 - 0.022 14.8 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 BetR domain Dynein_attach_N PF15867.5 CDJ37240.1 - 4.2e-13 49.0 0.3 1e-12 47.8 0.3 1.6 1 0 0 1 1 1 1 Dynein attachment factor N-terminus RPAP3_C PF13877.6 CDJ37240.1 - 1.5e-06 28.7 0.1 1.6e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 tRNA-synt_2 PF00152.20 CDJ37241.1 - 1.3e-61 208.4 0.0 2.6e-61 207.4 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ37241.1 - 2.6e-06 27.3 0.0 8.4e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2722 PF10846.8 CDJ37241.1 - 0.00059 18.9 1.1 0.00059 18.9 1.1 2.3 2 2 1 3 3 3 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ37241.1 - 0.012 15.3 2.9 0.012 15.3 2.9 1.7 2 0 0 2 2 2 0 Spt20 family Velvet PF11754.8 CDJ37241.1 - 0.11 12.4 7.6 8.3 6.3 1.8 3.4 3 1 0 3 3 3 0 Velvet factor SPX PF03105.19 CDJ37241.1 - 0.13 12.1 11.6 13 5.6 11.5 2.2 1 1 0 1 1 1 0 SPX domain tRNA-synt_2d PF01409.20 CDJ37241.1 - 0.23 10.9 0.0 0.54 9.7 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Secretin_N_2 PF07655.13 CDJ37241.1 - 2.7 8.6 28.9 4.8 7.8 4.3 4.5 4 0 0 4 4 4 0 Secretin N-terminal domain Aminotran_5 PF00266.19 CDJ37242.1 - 2.7e-71 240.5 0.0 5.2e-50 170.4 0.0 2.3 1 1 1 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CDJ37242.1 - 5.6e-05 22.6 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 CDJ37242.1 - 0.0073 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF725 PF05267.12 CDJ37242.1 - 0.044 13.8 0.5 0.11 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF725) ING PF12998.7 CDJ37245.1 - 1.5e-07 31.9 2.0 1.5e-07 31.9 2.0 2.3 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding DUF5479 PF17575.2 CDJ37245.1 - 0.083 13.5 3.5 0.17 12.5 3.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5479) Med15 PF09606.10 CDJ37245.1 - 10 4.7 54.9 13 4.3 54.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CTP_transf_like PF01467.26 CDJ37247.1 - 3.5e-12 46.7 1.6 2.8e-05 24.3 2.9 2.7 1 1 1 2 2 2 2 Cytidylyltransferase-like SPX PF03105.19 CDJ37247.1 - 0.00051 20.1 32.7 0.015 15.2 21.0 2.3 2 0 0 2 2 2 2 SPX domain Presenilin PF01080.17 CDJ37247.1 - 0.0011 17.9 11.1 0.0011 17.9 11.1 3.0 3 0 0 3 3 3 1 Presenilin RR_TM4-6 PF06459.12 CDJ37247.1 - 0.026 14.4 30.8 0.27 11.0 15.7 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4235 PF14019.6 CDJ37247.1 - 0.081 13.0 4.2 0.46 10.6 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) Zip PF02535.22 CDJ37247.1 - 0.29 10.3 26.7 0.0071 15.6 3.8 3.0 3 0 0 3 3 3 0 ZIP Zinc transporter NPR3 PF03666.13 CDJ37247.1 - 2 7.1 35.0 0.019 13.8 8.0 2.8 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.16 CDJ37247.1 - 2.3 7.6 27.2 0.03 13.8 2.2 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 FAM60A PF15396.6 CDJ37247.1 - 2.5 8.1 30.5 0.018 15.0 6.4 3.1 3 0 0 3 3 3 0 Protein Family FAM60A CLN3 PF02487.17 CDJ37247.1 - 6.7 5.6 20.6 1.6 7.7 7.2 2.3 2 0 0 2 2 2 0 CLN3 protein Hamartin PF04388.12 CDJ37247.1 - 6.7 5.2 39.4 0.55 8.8 28.9 2.3 2 0 0 2 2 2 0 Hamartin protein eIF-3_zeta PF05091.12 CDJ37247.1 - 9.8 5.0 42.0 1.3 7.9 11.7 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RRM_1 PF00076.22 CDJ37248.1 - 3e-09 36.6 0.0 3.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CDJ37248.1 - 0.061 13.4 0.0 0.068 13.3 0.0 1.1 1 0 0 1 1 1 0 Limkain b1 DUF2623 PF11115.8 CDJ37248.1 - 0.07 13.2 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) RRM_5 PF13893.6 CDJ37248.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelK_SelG PF10961.8 CDJ37249.1 - 0.012 16.2 4.1 0.45 11.2 1.3 3.0 3 0 0 3 3 3 0 Selenoprotein SelK_SelG SUIM_assoc PF16619.5 CDJ37249.1 - 0.014 15.5 3.4 0.014 15.5 3.4 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ37249.1 - 0.072 13.1 12.4 0.11 12.5 12.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF775 PF05603.12 CDJ37249.1 - 0.19 11.3 1.8 0.4 10.2 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Spt20 PF12090.8 CDJ37249.1 - 0.3 10.7 8.4 0.43 10.1 8.4 1.2 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 CDJ37249.1 - 5.3 6.6 20.1 2.7 7.6 1.9 2.3 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein RtcB PF01139.17 CDJ37250.1 - 7.2e-79 265.9 7.8 2.4e-77 260.9 0.2 2.7 1 1 2 3 3 3 2 tRNA-splicing ligase RtcB TFIIA PF03153.13 CDJ37250.1 - 0.0015 18.7 9.4 0.0018 18.4 9.4 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ37250.1 - 0.021 15.8 2.9 0.043 14.8 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) eIF-3_zeta PF05091.12 CDJ37250.1 - 0.031 13.2 2.2 0.04 12.9 2.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 CDJ37250.1 - 0.12 12.3 4.5 0.17 11.8 4.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ37250.1 - 0.22 10.2 0.4 0.27 9.9 0.4 1.2 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ37250.1 - 0.3 10.7 20.9 0.45 10.1 20.9 1.2 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ37250.1 - 1.2 8.0 19.3 1.7 7.5 19.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) UPF0560 PF10577.9 CDJ37250.1 - 1.2 7.5 8.1 1.7 7.0 8.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Yip1 PF04893.17 CDJ37251.1 - 2.1e-10 40.6 8.2 4.1e-10 39.6 8.2 1.5 1 0 0 1 1 1 1 Yip1 domain FeoB_Cyto PF17910.1 CDJ37252.1 - 0.032 14.8 5.3 0.036 14.6 3.6 1.8 1 1 1 2 2 2 0 FeoB cytosolic helical domain PYC_OADA PF02436.18 CDJ37252.1 - 0.061 13.1 1.5 0.066 12.9 1.5 1.2 1 0 0 1 1 1 0 Conserved carboxylase domain TMPIT PF07851.13 CDJ37252.1 - 0.083 12.1 3.2 0.091 12.0 3.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 CDJ37252.1 - 0.086 13.2 11.0 0.11 12.9 11.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MRP-S31 PF15433.6 CDJ37252.1 - 0.14 11.8 8.2 0.14 11.8 8.2 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF4407 PF14362.6 CDJ37252.1 - 0.79 9.0 6.0 0.88 8.9 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YebO PF13974.6 CDJ37252.1 - 4.7 7.4 11.9 1 9.5 2.5 2.2 2 0 0 2 2 2 0 YebO-like protein GTA_holin_3TM PF11351.8 CDJ37252.1 - 5 7.7 8.0 13 6.3 8.0 1.7 1 1 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Myb_DNA-binding PF00249.31 CDJ37253.1 - 9.2e-22 77.0 0.0 7.4e-09 35.7 0.0 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ37253.1 - 2.7e-15 56.3 0.0 0.00017 21.8 0.0 3.7 2 1 1 3 3 3 3 Myb-like DNA-binding domain Pkinase PF00069.25 CDJ37256.1 - 2.4e-52 177.9 0.0 1.2e-50 172.3 0.0 3.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37256.1 - 3.7e-34 118.2 0.1 1.8e-32 112.7 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase EF-hand_11 PF08976.11 CDJ37256.1 - 2.2e-05 25.2 0.0 6.7e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain HA2 PF04408.23 CDJ37257.1 - 3.8e-26 91.5 0.2 2e-25 89.2 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ37257.1 - 1.7e-22 79.5 0.0 4.4e-22 78.2 0.0 1.7 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ37257.1 - 6.6e-10 39.3 0.0 1.5e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 CDJ37257.1 - 2.6e-07 30.9 0.0 6.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 CDJ37257.1 - 6.3e-06 26.1 0.1 1.7e-05 24.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ37257.1 - 3.5e-05 24.1 0.0 0.00011 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ37257.1 - 0.0011 18.8 0.0 0.0047 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDJ37257.1 - 0.0023 18.3 0.0 0.0059 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CDJ37257.1 - 0.0086 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 CDJ37257.1 - 0.017 14.2 0.5 0.049 12.7 0.2 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.16 CDJ37257.1 - 0.025 14.0 0.2 0.14 11.6 0.2 2.2 2 0 0 2 2 2 0 PhoH-like protein Microtub_bd PF16796.5 CDJ37257.1 - 0.11 12.4 0.0 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 Microtubule binding AAA_16 PF13191.6 CDJ37257.1 - 1.1 9.6 5.7 0.44 10.9 0.1 3.0 4 0 0 4 4 4 0 AAA ATPase domain SUI1 PF01253.22 CDJ37258.1 - 1.7e-26 92.5 0.4 2.6e-26 92.0 0.4 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.14 CDJ37258.1 - 0.19 12.0 0.1 0.29 11.5 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) RNase_PH PF01138.21 CDJ37259.1 - 4.2e-10 40.2 0.0 6.9e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CDJ37259.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 KH_1 PF00013.29 CDJ37260.1 - 0.0084 15.9 0.0 0.92 9.4 0.0 2.6 2 0 0 2 2 2 2 KH domain VHS PF00790.19 CDJ37260.1 - 0.015 15.2 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 VHS domain UFC1 PF08694.11 CDJ37262.1 - 1.4e-77 258.6 0.1 1.6e-77 258.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 CDJ37262.1 - 0.0035 17.0 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDJ37262.1 - 0.02 15.1 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain Glyco_hydro_61 PF03443.14 CDJ37262.1 - 0.071 13.0 0.0 0.091 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 PAP_assoc PF03828.19 CDJ37263.1 - 2.7e-05 24.3 0.3 0.00052 20.2 0.2 2.5 2 0 0 2 2 2 1 Cid1 family poly A polymerase SRP-alpha_N PF04086.13 CDJ37264.1 - 0.04 13.9 1.0 0.046 13.6 1.0 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PGA2 PF07543.12 CDJ37264.1 - 4 7.4 6.5 7.7 6.5 6.5 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF4604 PF15377.6 CDJ37264.1 - 9.1 6.7 13.1 1.3 9.5 8.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Exo_endo_phos PF03372.23 CDJ37265.1 - 5e-07 29.5 0.0 3.6e-06 26.7 0.0 2.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SPX PF03105.19 CDJ37265.1 - 0.19 11.6 18.9 0.017 15.0 1.3 2.3 2 0 0 2 2 2 0 SPX domain DUF368 PF04018.13 CDJ37266.1 - 0.087 12.4 1.9 0.19 11.3 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF368) DUF5523 PF17661.1 CDJ37266.1 - 8.2 6.0 20.9 21 4.7 20.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5523) EF-hand_8 PF13833.6 CDJ37267.1 - 0.0011 18.8 0.2 0.0025 17.6 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 CDJ37267.1 - 0.0022 18.4 0.4 0.0047 17.4 0.4 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ37267.1 - 0.039 13.5 1.5 0.72 9.5 0.7 2.5 2 0 0 2 2 2 0 EF hand SR-25 PF10500.9 CDJ37267.1 - 0.13 11.8 11.0 0.19 11.3 11.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EF-hand_6 PF13405.6 CDJ37267.1 - 0.21 11.6 1.0 8.1 6.7 0.4 2.6 2 0 0 2 2 2 0 EF-hand domain Chorion_2 PF03964.15 CDJ37268.1 - 0.012 16.4 6.8 0.012 16.4 6.8 4.4 2 1 1 3 3 3 0 Chorion family 2 SR-25 PF10500.9 CDJ37268.1 - 0.65 9.6 15.6 0.027 14.1 9.0 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MaoC_dehydratas PF01575.19 CDJ37269.1 - 4.6e-05 23.0 0.4 0.00032 20.3 0.8 2.1 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CDJ37269.1 - 0.00069 19.8 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase PAP1 PF08601.10 CDJ37269.1 - 0.12 12.1 10.5 0.16 11.7 10.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Apt1 PF10351.9 CDJ37269.1 - 0.39 9.5 6.3 0.47 9.2 6.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dehydrin PF00257.19 CDJ37269.1 - 1 9.9 17.1 0.19 12.2 12.6 1.9 2 0 0 2 2 2 0 Dehydrin GREB1 PF15782.5 CDJ37269.1 - 1.3 6.0 9.8 1.7 5.7 9.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MDFI PF15316.6 CDJ37269.1 - 1.4 9.0 7.1 2.3 8.3 7.1 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Presenilin PF01080.17 CDJ37269.1 - 2.9 6.6 9.1 4.2 6.0 9.1 1.1 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.11 CDJ37269.1 - 3.7 6.9 4.1 4.8 6.5 4.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Noc2 PF03715.13 CDJ37273.1 - 4.5e-26 91.8 0.2 4.5e-26 91.8 0.2 1.8 2 0 0 2 2 2 1 Noc2p family SUIM_assoc PF16619.5 CDJ37273.1 - 0.055 13.5 0.0 0.055 13.5 0.0 8.7 8 3 0 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 NEMP PF10225.9 CDJ37274.1 - 3.8 7.1 9.8 1.1 8.9 5.1 2.4 2 0 0 2 2 2 0 NEMP family MRP-L47 PF06984.13 CDJ37275.1 - 4.5e-26 90.8 0.4 4.5e-26 90.8 0.4 1.9 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 CDJ37275.1 - 0.00016 21.6 1.5 0.00016 21.6 1.5 2.6 3 0 0 3 3 3 1 Ribosomal L29 protein DUF2175 PF09943.9 CDJ37275.1 - 0.11 12.8 1.9 0.32 11.3 1.5 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) EMP70 PF02990.16 CDJ37276.1 - 6.9e-64 216.4 0.0 4.5e-61 207.1 0.0 2.3 2 0 0 2 2 2 2 Endomembrane protein 70 SR-25 PF10500.9 CDJ37276.1 - 0.0083 15.8 1.1 0.0083 15.8 1.1 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ37276.1 - 0.049 13.6 24.9 0.077 13.0 24.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 CDJ37276.1 - 2.5 6.1 6.4 3.6 5.6 6.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1180 PF06679.12 CDJ37277.1 - 0.0039 17.6 3.6 0.0043 17.5 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) YjbE PF11106.8 CDJ37277.1 - 0.07 13.4 10.3 0.14 12.4 10.3 1.5 1 1 0 1 1 1 0 Exopolysaccharide production protein YjbE Sox_N PF12444.8 CDJ37277.1 - 0.79 10.9 4.7 2.2 9.5 4.7 1.7 1 1 0 1 1 1 0 Sox developmental protein N terminal DUF1180 PF06679.12 CDJ37278.1 - 8.1 6.8 7.9 10 6.5 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) FAM199X PF15814.5 CDJ37279.1 - 0.051 12.6 7.5 0.071 12.2 7.5 1.2 1 0 0 1 1 1 0 Protein family FAM199X tRNA_lig_CPD PF08302.11 CDJ37279.1 - 0.42 10.0 5.9 0.56 9.6 5.9 1.2 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Presenilin PF01080.17 CDJ37279.1 - 0.87 8.3 6.4 0.84 8.3 6.4 1.2 1 0 0 1 1 1 0 Presenilin RskA PF10099.9 CDJ37279.1 - 1.1 9.5 21.4 0.76 10.0 7.4 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF4770 PF15994.5 CDJ37279.1 - 1.6 8.9 11.1 2.2 8.5 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4834 PF16118.5 CDJ37279.1 - 4.1 8.4 9.4 8.1 7.5 6.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Cwf_Cwc_15 PF04889.12 CDJ37279.1 - 8.8 6.0 16.8 17 5.0 16.8 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Rpn3_C PF08375.11 CDJ37281.1 - 2.1e-21 76.1 3.3 5.3e-21 74.8 3.3 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CDJ37281.1 - 2.3e-21 76.3 1.2 8.1e-21 74.5 0.1 2.3 2 0 0 2 2 2 1 PCI domain CCDC32 PF14989.6 CDJ37281.1 - 0.031 14.3 2.9 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing 32 TMEM101 PF15111.6 CDJ37282.1 - 0.056 13.0 1.8 0.093 12.3 1.8 1.3 1 0 0 1 1 1 0 TMEM101 protein family Claudin_2 PF13903.6 CDJ37282.1 - 0.13 12.0 3.9 0.19 11.5 3.9 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF5345 PF17280.2 CDJ37282.1 - 0.23 11.5 0.8 0.5 10.4 0.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5345) SNARE_assoc PF09335.11 CDJ37282.1 - 0.29 11.6 5.3 0.67 10.4 5.2 1.7 1 1 0 1 1 1 0 SNARE associated Golgi protein TraL PF07178.11 CDJ37282.1 - 5.6 7.5 6.7 11 6.6 6.7 1.4 1 0 0 1 1 1 0 TraL protein DTW PF03942.15 CDJ37283.1 - 1.2e-21 77.3 5.6 4.6e-21 75.4 5.6 1.9 1 1 0 1 1 1 1 DTW domain DUF4512 PF14975.6 CDJ37283.1 - 0.044 14.6 0.1 0.27 12.1 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) RR_TM4-6 PF06459.12 CDJ37283.1 - 5.2 6.8 7.0 11 5.7 1.0 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Ecm29 PF13001.7 CDJ37284.1 - 0.073 11.7 0.1 0.098 11.3 0.1 1.1 1 0 0 1 1 1 0 Proteasome stabiliser HEAT PF02985.22 CDJ37285.1 - 0.029 14.6 11.7 0.059 13.6 0.1 6.2 5 0 0 5 5 5 0 HEAT repeat Vac14_Fab1_bd PF12755.7 CDJ37285.1 - 0.053 14.1 0.0 2.3 8.8 0.0 2.6 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.7 CDJ37285.1 - 0.11 12.8 0.0 0.43 10.9 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 CDJ37285.1 - 0.2 12.2 0.0 0.2 12.2 0.0 6.4 6 0 0 6 6 6 0 HEAT-like repeat PBP PF01161.20 CDJ37286.1 - 4.9e-06 26.9 0.0 7.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SAWADEE PF16719.5 CDJ37286.1 - 0.037 14.0 0.0 8.8 6.3 0.0 2.2 2 0 0 2 2 2 0 SAWADEE domain SpoIIE PF07228.12 CDJ37287.1 - 0.014 15.3 0.0 0.062 13.2 0.0 2.0 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) RNase_H PF00075.24 CDJ37288.1 - 4.8e-30 104.6 0.0 4.1e-29 101.6 0.0 2.0 1 1 0 1 1 1 1 RNase H Guanylate_kin PF00625.21 CDJ37289.1 - 1.7e-49 168.0 0.0 2e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 CDJ37289.1 - 2.9e-05 24.5 0.1 5.1e-05 23.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CDJ37289.1 - 0.00026 21.6 0.5 0.002 18.7 0.5 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CDJ37289.1 - 0.00047 20.1 0.0 0.00079 19.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 CDJ37289.1 - 0.0031 17.7 0.9 0.053 13.7 0.9 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ37289.1 - 0.0073 16.6 0.0 0.048 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDJ37289.1 - 0.012 15.4 0.1 0.028 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CDJ37289.1 - 0.027 14.4 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 CDJ37289.1 - 0.038 13.9 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 CDJ37289.1 - 0.071 13.2 0.0 0.1 12.7 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 CDJ37289.1 - 0.12 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 NTPase DUF588 PF04535.12 CDJ37291.1 - 0.11 12.3 4.2 0.19 11.5 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF588) RRM_1 PF00076.22 CDJ37293.1 - 5.4e-23 80.6 0.1 1.2e-17 63.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.9 CDJ37293.1 - 0.021 14.0 4.6 0.026 13.7 4.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Glyoxalase_5 PF14696.6 CDJ37293.1 - 0.052 13.7 0.7 0.14 12.3 0.7 1.8 1 1 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF1866 PF08952.11 CDJ37293.1 - 0.056 13.3 0.0 0.4 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) RRM_7 PF16367.5 CDJ37293.1 - 0.086 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif DUF1543 PF07566.12 CDJ37293.1 - 0.13 12.0 0.8 0.5 10.1 0.8 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) Limkain-b1 PF11608.8 CDJ37293.1 - 0.16 12.1 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 Spt20 PF12090.8 CDJ37293.1 - 2.1 7.9 5.2 3.1 7.3 5.2 1.2 1 0 0 1 1 1 0 Spt20 family RRM_1 PF00076.22 CDJ37294.1 - 3.6e-05 23.5 0.0 8.5e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF2A PF08662.11 CDJ37294.1 - 0.019 14.9 0.2 0.052 13.4 0.1 1.6 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A NPIP PF06409.11 CDJ37294.1 - 0.44 9.6 1.8 0.72 8.9 1.8 1.3 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Cullin PF00888.22 CDJ37295.1 - 4.9e-28 98.1 12.5 4.7e-25 88.3 10.4 5.1 5 1 0 5 5 5 3 Cullin family eIF-3_zeta PF05091.12 CDJ37296.1 - 3.5e-141 471.7 0.0 4.4e-141 471.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 CDJ37296.1 - 0.051 13.1 0.2 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus ATP_bind_1 PF03029.17 CDJ37297.1 - 3.7e-66 223.3 0.0 2.7e-61 207.4 0.0 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CDJ37297.1 - 5.7e-05 23.7 0.1 0.00056 20.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Ribosomal_60s PF00428.19 CDJ37297.1 - 0.00012 22.6 6.9 0.00022 21.8 5.2 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein AAA_16 PF13191.6 CDJ37297.1 - 0.00016 22.1 2.5 0.00096 19.6 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDJ37297.1 - 0.00019 21.7 0.0 0.00057 20.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 CDJ37297.1 - 0.0038 17.7 0.0 0.0098 16.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter PduV-EutP PF10662.9 CDJ37297.1 - 0.0049 16.6 0.0 0.048 13.4 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 CDJ37297.1 - 0.0078 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA12 PF10443.9 CDJ37297.1 - 0.0078 15.0 0.0 0.31 9.7 0.0 2.1 2 0 0 2 2 2 1 RNA12 protein AAA_5 PF07728.14 CDJ37297.1 - 0.009 16.0 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 CDJ37297.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CDJ37297.1 - 0.014 15.1 0.0 0.049 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 CDJ37297.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 CDJ37297.1 - 0.017 15.1 0.0 0.045 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDJ37297.1 - 0.028 14.2 0.1 0.07 12.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 CDJ37297.1 - 0.033 14.6 0.0 0.24 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CDJ37297.1 - 0.041 13.2 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Cytidylate_kin PF02224.18 CDJ37297.1 - 0.041 13.6 0.4 0.091 12.5 0.0 1.7 2 0 0 2 2 1 0 Cytidylate kinase RNA_helicase PF00910.22 CDJ37297.1 - 0.042 14.2 0.0 0.081 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 CDJ37297.1 - 0.049 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 CDJ37297.1 - 0.05 12.8 0.0 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 CDJ37297.1 - 0.056 13.3 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 CDJ37297.1 - 0.067 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 CDJ37297.1 - 0.076 13.1 0.0 5.4 7.0 0.0 3.0 2 1 1 3 3 3 0 Dynamin family Pox_Ag35 PF03286.14 CDJ37297.1 - 0.092 12.5 7.0 0.15 11.9 7.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Gtr1_RagA PF04670.12 CDJ37297.1 - 0.14 11.4 0.0 0.48 9.7 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region NACHT PF05729.12 CDJ37297.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.17 CDJ37297.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain CbiA PF01656.23 CDJ37297.1 - 0.18 11.9 0.0 0.29 11.2 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RRN3 PF05327.11 CDJ37297.1 - 0.38 9.2 6.3 0.52 8.8 6.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 CDJ37297.1 - 1.7 8.3 8.6 4.5 6.9 8.6 1.8 1 1 0 1 1 1 0 FAM176 family Pkinase PF00069.25 CDJ37298.1 - 5.9e-18 65.2 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37298.1 - 1e-06 28.3 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ37298.1 - 0.00048 19.5 0.0 0.00084 18.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ37298.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRF PF01765.19 CDJ37298.1 - 0.63 10.0 3.2 0.67 9.9 1.6 1.8 2 0 0 2 2 2 0 Ribosome recycling factor Pkinase PF00069.25 CDJ37299.1 - 4.6e-19 68.8 0.0 8.5e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ37299.1 - 7.5e-06 25.5 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ37299.1 - 9.1e-06 25.1 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ37299.1 - 0.023 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ37299.1 - 0.034 14.1 0.1 0.034 14.1 0.1 3.0 2 2 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 CDJ37300.1 - 8.2e-23 81.1 0.0 1.6e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ37300.1 - 6.9e-13 48.6 0.0 1.1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ37300.1 - 3.8e-11 42.8 0.0 6.4e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ37300.1 - 0.00012 21.6 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ37300.1 - 0.0016 18.5 0.5 0.0016 18.5 0.5 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family PIP49_C PF12260.8 CDJ37300.1 - 0.042 13.5 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 MoaE PF02391.17 CDJ37300.1 - 0.24 11.7 1.6 0.96 9.8 0.0 2.7 4 0 0 4 4 4 0 MoaE protein SR-25 PF10500.9 CDJ37301.1 - 0.73 9.4 11.9 1.1 8.8 11.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Gaa1 PF04114.14 CDJ37302.1 - 1.4e-06 27.6 6.4 0.29 10.1 0.6 5.5 4 1 1 5 5 5 2 Gaa1-like, GPI transamidase component DUF2722 PF10846.8 CDJ37302.1 - 1.4 7.8 23.3 0.53 9.2 1.2 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ37302.1 - 2.6 6.7 8.7 0.061 12.1 1.5 2.0 2 0 0 2 2 2 0 Presenilin DUF2207 PF09972.9 CDJ37302.1 - 3 6.5 9.2 3.8 6.2 0.0 3.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) PDCD9 PF07147.12 CDJ37302.1 - 3 6.9 9.7 0.078 12.2 2.8 1.8 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) CSG2 PF16965.5 CDJ37302.1 - 5.4 5.8 5.0 0.57 9.1 0.2 1.7 2 0 0 2 2 2 0 Ceramide synthase regulator DUF3675 PF12428.8 CDJ37302.1 - 10 6.7 6.7 5.1 7.7 0.4 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Sporozoite_P67 PF05642.11 CDJ37304.1 - 0.00057 18.1 3.0 0.00063 18.0 3.0 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen AP2 PF00847.20 CDJ37304.1 - 0.0025 18.0 1.4 0.0025 18.0 1.4 2.9 4 0 0 4 4 4 1 AP2 domain SR-25 PF10500.9 CDJ37305.1 - 0.26 10.9 13.2 0.31 10.6 2.0 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein NifU PF01106.17 CDJ37306.1 - 8e-25 86.8 0.1 2.2e-24 85.4 0.0 1.7 2 0 0 2 2 2 1 NifU-like domain Nfu_N PF08712.11 CDJ37306.1 - 4.3e-21 74.8 0.0 8.5e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal Sigma70_ner PF04546.13 CDJ37306.1 - 0.038 13.9 2.5 0.056 13.3 2.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RskA PF10099.9 CDJ37306.1 - 0.49 10.7 19.4 1.4 9.2 9.3 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA adh_short PF00106.25 CDJ37307.1 - 1.9e-44 151.4 10.4 4.6e-38 130.7 0.5 2.9 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ37307.1 - 1.1e-35 123.3 14.0 8e-33 113.9 0.5 3.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 CDJ37307.1 - 9.6e-30 103.1 4.1 1.1e-17 64.4 0.0 3.9 4 0 0 4 4 4 2 SCP-2 sterol transfer family KR PF08659.10 CDJ37307.1 - 1.1e-11 45.0 9.7 1.1e-11 45.0 9.7 3.4 3 1 0 3 3 3 1 KR domain Alkyl_sulf_C PF14864.6 CDJ37307.1 - 0.0013 19.0 0.0 2.6 8.3 0.0 3.0 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal DUF2722 PF10846.8 CDJ37307.1 - 0.0042 16.1 2.4 0.12 11.3 0.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) 3HCDH_N PF02737.18 CDJ37307.1 - 0.026 14.4 2.4 0.061 13.2 2.4 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Spt20 PF12090.8 CDJ37307.1 - 0.25 10.9 18.3 0.37 10.4 8.8 2.3 2 0 0 2 2 2 0 Spt20 family Macoilin PF09726.9 CDJ37307.1 - 0.93 8.0 11.0 0.041 12.5 4.0 2.0 2 0 0 2 2 2 0 Macoilin family FAD_binding_2 PF00890.24 CDJ37307.1 - 9.7 5.1 16.6 0.021 13.9 6.6 1.6 2 0 0 2 2 2 0 FAD binding domain Aquarius_N PF16399.5 CDJ37308.1 - 7.9e-126 421.1 0.0 5.9e-88 295.8 0.0 6.3 7 1 0 7 7 7 2 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 CDJ37308.1 - 5.6e-23 81.6 0.0 5.6e-23 81.6 0.0 3.7 4 1 0 4 4 4 1 AAA domain AAA_11 PF13086.6 CDJ37308.1 - 2.9e-15 56.8 58.4 3e-14 53.4 10.4 9.9 6 3 1 7 7 7 2 AAA domain AAA_22 PF13401.6 CDJ37308.1 - 0.00078 19.7 0.0 0.00078 19.7 0.0 4.1 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 CDJ37308.1 - 0.0023 17.7 0.2 0.0069 16.2 0.2 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ATPase PF06745.13 CDJ37308.1 - 0.003 16.9 0.0 0.0095 15.3 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_5 PF07728.14 CDJ37308.1 - 0.037 14.0 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RskA PF10099.9 CDJ37308.1 - 0.042 14.1 0.1 0.042 14.1 0.1 21.6 8 5 9 19 19 19 0 Anti-sigma-K factor rskA AAA PF00004.29 CDJ37308.1 - 0.16 12.4 0.4 1.8 9.0 0.0 3.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sin_N PF04801.13 CDJ37308.1 - 9.7 5.3 0.0 0.031 13.5 20.7 10.6 5 3 4 10 10 10 0 Sin-like protein conserved region CEP44 PF15007.6 CDJ37309.1 - 2.9e-19 69.5 0.0 3.8e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Herpes_capsid PF06112.11 CDJ37310.1 - 5.2 7.1 16.4 2.6 8.1 14.5 1.4 1 1 0 1 1 1 0 Gammaherpesvirus capsid protein Mannitol_dh_C PF08125.13 CDJ37311.1 - 4.7e-37 127.8 0.0 5.3e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Adaptin_binding PF10199.9 CDJ37312.1 - 9.8e-09 35.9 8.3 9.8e-09 35.9 8.3 2.9 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 DUF2722 PF10846.8 CDJ37312.1 - 5.6e-05 22.3 6.4 5.6e-05 22.3 6.4 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ37312.1 - 0.0074 15.9 10.8 0.0074 15.9 10.8 4.6 2 1 2 4 4 4 1 Nuclear RNA-splicing-associated protein SDA1 PF05285.12 CDJ37312.1 - 2.9 7.2 25.5 2.9 7.2 5.7 2.2 2 0 0 2 2 2 0 SDA1 RR_TM4-6 PF06459.12 CDJ37312.1 - 3 7.6 28.6 3.2 7.5 7.4 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 EOS1 PF12326.8 CDJ37312.1 - 3.2 7.7 12.1 0.9 9.4 3.3 2.4 2 0 0 2 2 2 0 N-glycosylation protein Utp14 PF04615.13 CDJ37312.1 - 7 5.1 30.0 13 4.2 30.1 1.4 1 1 0 1 1 1 0 Utp14 protein E_Pc_C PF06752.12 CDJ37313.1 - 0.0057 16.8 11.7 0.012 15.8 11.7 1.5 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus DUF2240 PF09999.9 CDJ37313.1 - 0.017 14.8 0.1 0.048 13.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) Rotamase_2 PF13145.6 CDJ37313.1 - 0.073 13.9 5.7 0.1 13.4 0.1 2.6 2 0 0 2 2 2 0 PPIC-type PPIASE domain Rhomboid_N PF12122.8 CDJ37313.1 - 0.086 13.0 2.3 0.18 12.0 2.3 1.4 1 0 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease CBM_14 PF01607.24 CDJ37314.1 - 0.036 14.2 0.1 0.067 13.4 0.1 1.4 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain dCache_1 PF02743.18 CDJ37315.1 - 0.39 10.5 1.5 0.64 9.8 0.5 1.7 2 0 0 2 2 2 0 Cache domain RskA PF10099.9 CDJ37316.1 - 0.0056 17.0 4.4 0.011 16.0 4.4 1.6 1 1 0 1 1 1 1 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ37316.1 - 0.0084 17.0 2.1 1.2 10.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) WBP-1 PF11669.8 CDJ37316.1 - 0.016 15.8 0.2 0.016 15.8 0.2 2.4 2 1 1 3 3 3 0 WW domain-binding protein 1 Trp_oprn_chp PF09534.10 CDJ37316.1 - 0.087 12.6 0.2 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF92 PF01940.16 CDJ37316.1 - 0.17 11.3 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 DivIC PF04977.15 CDJ37316.1 - 0.69 9.7 12.9 0.2 11.4 1.4 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF2722 PF10846.8 CDJ37316.1 - 0.79 8.6 11.9 0.46 9.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ37316.1 - 0.92 9.1 21.1 2.7 7.5 3.4 2.1 2 0 0 2 2 2 0 Spt20 family Histone_HNS PF00816.21 CDJ37316.1 - 1.8 9.4 8.6 0.85 10.5 0.1 2.5 2 1 0 2 2 2 0 H-NS histone family Proteasom_PSMB PF10508.9 CDJ37317.1 - 1.2e-12 47.2 3.5 5.3e-07 28.5 2.4 2.1 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit SAPS PF04499.15 CDJ37317.1 - 0.099 11.4 0.1 0.18 10.5 0.1 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein U3snoRNP10 PF12397.8 CDJ37317.1 - 1.2 9.5 7.5 1.6 9.1 0.1 3.7 4 1 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 Lin-8 PF03353.15 CDJ37318.1 - 3.4 7.2 4.9 0.99 8.9 1.4 1.9 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Peptidase_M16_C PF05193.21 CDJ37319.1 - 2.2e-33 115.8 0.0 5.1e-33 114.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDJ37319.1 - 5.7e-25 88.0 0.0 3.3e-24 85.6 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) PIGA PF08288.12 CDJ37319.1 - 0.074 13.7 0.0 1.9 9.2 0.0 2.5 2 0 0 2 2 2 0 PIGA (GPI anchor biosynthesis) Jiraiya PF15038.6 CDJ37320.1 - 0.0001 21.8 1.9 0.00013 21.5 1.9 1.2 1 0 0 1 1 1 1 Jiraiya SLH PF00395.20 CDJ37320.1 - 0.078 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 S-layer homology domain Orai-1 PF07856.12 CDJ37320.1 - 0.15 11.7 10.1 1.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Mediator of CRAC channel activity TMEM171 PF15471.6 CDJ37320.1 - 0.31 10.0 1.3 0.44 9.5 1.3 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 PIG-P PF08510.12 CDJ37320.1 - 1.7 8.6 0.0 1.7 8.6 0.0 2.9 2 2 1 3 3 3 0 PIG-P MFS_1 PF07690.16 CDJ37321.1 - 1.5e-20 73.4 63.7 8.2e-18 64.4 9.0 4.5 3 1 1 4 4 4 3 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ37321.1 - 6.1e-13 48.4 1.9 6.1e-13 48.4 1.9 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 CDJ37321.1 - 0.0017 16.8 30.9 0.0068 14.7 5.4 4.9 4 1 1 5 5 5 4 Organic Anion Transporter Polypeptide (OATP) family DUF4128 PF13554.6 CDJ37322.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function AP2 PF00847.20 CDJ37323.1 - 3.5e-23 81.6 13.4 4.1e-10 39.7 0.0 5.1 4 0 0 4 4 4 3 AP2 domain DUF2515 PF10720.9 CDJ37323.1 - 0.3 10.2 6.5 0.54 9.4 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2515) WD40 PF00400.32 CDJ37324.1 - 0.25 12.3 1.2 22 6.1 0.0 4.0 3 0 0 3 3 3 0 WD domain, G-beta repeat TGT PF01702.18 CDJ37325.1 - 4.3e-09 36.0 0.1 1.1e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase SID-1_RNA_chan PF13965.6 CDJ37325.1 - 0.9 7.9 2.1 1.5 7.1 2.1 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TFIIF_alpha PF05793.12 CDJ37325.1 - 1.5 7.3 28.3 3.8 6.0 28.3 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4746 PF15928.5 CDJ37325.1 - 9.1 5.6 17.9 3.1 7.2 13.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Ribosomal_L7Ae PF01248.26 CDJ37326.1 - 2.2e-25 88.2 0.3 2.9e-25 87.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CDJ37326.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CDJ37326.1 - 0.064 13.3 0.0 0.073 13.1 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 RskA PF10099.9 CDJ37327.1 - 9.6e-05 22.7 2.8 0.00032 21.1 2.5 1.9 1 1 0 1 1 1 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ37327.1 - 0.1 12.2 10.7 0.15 11.6 10.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ37327.1 - 0.32 10.9 20.5 0.37 10.7 20.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NUC194 PF08163.12 CDJ37327.1 - 0.46 9.4 5.4 0.51 9.2 5.4 1.1 1 0 0 1 1 1 0 NUC194 domain MDFI PF15316.6 CDJ37327.1 - 1 9.4 5.8 1.4 8.9 5.8 1.3 1 0 0 1 1 1 0 MyoD family inhibitor GREB1 PF15782.5 CDJ37327.1 - 3.2 4.7 12.9 3.4 4.7 12.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer IMUP PF15761.5 CDJ37327.1 - 4.7 8.0 14.4 1.2 9.9 10.6 1.9 1 1 0 2 2 2 0 Immortalisation up-regulated protein Lin-8 PF03353.15 CDJ37327.1 - 5 6.6 11.1 5.9 6.4 11.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ERCC3_RAD25_C PF16203.5 CDJ37328.1 - 1.6e-76 256.8 12.1 3.5e-44 150.9 0.1 2.3 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CDJ37328.1 - 5.6e-10 39.5 0.0 1.9e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 CDJ37328.1 - 0.0011 17.8 0.0 0.0026 16.5 0.0 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain RskA PF10099.9 CDJ37328.1 - 1.6 9.0 20.0 0.035 14.4 7.0 3.0 3 0 0 3 3 3 0 Anti-sigma-K factor rskA DUF3357 PF11837.8 CDJ37328.1 - 3.2 8.2 6.2 26 5.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) IHABP4_N PF16174.5 CDJ37328.1 - 3.5 8.2 15.6 1.3 9.6 7.5 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Spt20 PF12090.8 CDJ37329.1 - 0.46 10.1 15.9 0.48 10.0 15.9 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ37329.1 - 0.78 9.7 12.7 0.79 9.7 12.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RabGAP-TBC PF00566.18 CDJ37330.1 - 8e-48 162.9 0.0 8e-48 162.9 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SPX PF03105.19 CDJ37330.1 - 0.049 13.5 10.7 0.061 13.2 10.7 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 CDJ37330.1 - 0.053 12.1 10.6 0.074 11.6 10.6 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ37330.1 - 0.059 12.2 11.9 0.075 11.9 11.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RskA PF10099.9 CDJ37331.1 - 0.01 16.1 7.5 0.012 15.9 7.5 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF5585 PF17823.1 CDJ37331.1 - 0.038 13.0 5.7 0.047 12.7 5.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Med3 PF11593.8 CDJ37331.1 - 9.3 5.3 20.5 11 5.1 20.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF737 PF05300.11 CDJ37332.1 - 0.042 14.2 4.4 0.053 13.9 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF5588 PF17826.1 CDJ37332.1 - 7.5 5.3 11.5 3.1 6.6 8.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5588) DUF572 PF04502.13 CDJ37333.1 - 0.024 14.3 5.7 0.027 14.1 5.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) ANAPC_CDC26 PF10471.9 CDJ37333.1 - 0.096 13.5 0.4 0.096 13.5 0.4 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Roughex PF06020.11 CDJ37333.1 - 0.95 8.5 15.1 1.2 8.2 1.1 2.3 2 0 0 2 2 2 0 Drosophila roughex protein Hep_59 PF07052.11 CDJ37333.1 - 3.6 8.4 10.6 13 6.6 0.7 2.5 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 DAG_kinase_N PF14513.6 CDJ37333.1 - 7.4 6.8 17.0 0.11 12.7 2.2 2.2 1 1 1 2 2 2 0 Diacylglycerol kinase N-terminus DUF1840 PF08895.11 CDJ37333.1 - 7.4 7.0 13.2 4.3 7.7 5.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Chromo PF00385.24 CDJ37335.1 - 4.5e-05 23.3 0.2 0.0001 22.1 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ubiquitin PF00240.23 CDJ37336.1 - 7.8e-12 44.8 0.0 1.7e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CDJ37336.1 - 1.9e-06 27.6 0.7 4.5e-06 26.4 0.2 2.0 2 0 0 2 2 2 1 UBA/TS-N domain STI1 PF17830.1 CDJ37336.1 - 0.00028 20.7 2.2 0.064 13.2 0.3 2.7 1 1 1 2 2 2 2 STI1 domain Myc_N PF01056.18 CDJ37336.1 - 0.0061 16.5 9.0 0.0061 16.5 9.0 2.5 2 1 0 2 2 2 1 Myc amino-terminal region HOIP-UBA PF16678.5 CDJ37336.1 - 0.0071 16.4 0.2 0.0071 16.4 0.2 2.5 3 0 0 3 3 3 1 HOIP UBA domain pair CUE PF02845.16 CDJ37336.1 - 0.015 15.0 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 0 CUE domain DUF3246 PF11596.8 CDJ37336.1 - 0.073 12.5 5.1 0.15 11.5 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) TFIIE-A_C PF11521.8 CDJ37336.1 - 4.3 7.7 13.6 0.057 13.7 4.8 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha SWIB PF02201.18 CDJ37337.1 - 1.8e-22 79.0 0.1 3.1e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain SUIM_assoc PF16619.5 CDJ37337.1 - 0.0029 17.7 9.8 0.0029 17.7 9.8 2.8 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 Mit_KHE1 PF10173.9 CDJ37337.1 - 0.075 13.1 3.0 0.14 12.3 3.0 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related FPL PF09758.9 CDJ37338.1 - 3e-51 173.3 1.0 5.6e-51 172.4 1.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein BTB PF00651.31 CDJ37339.1 - 1.1e-05 25.6 0.0 2.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain RCC1 PF00415.18 CDJ37340.1 - 2.5e-26 92.0 14.1 1.7e-07 31.8 0.0 6.3 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ37340.1 - 8.3e-12 44.6 26.3 1.6e-10 40.5 0.6 6.1 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 CDJ37340.1 - 4.5e-09 35.3 44.3 0.00012 21.6 1.6 8.4 9 0 0 9 9 9 5 IQ calmodulin-binding motif Myosin_head PF00063.21 CDJ37340.1 - 0.00016 20.1 0.0 0.00022 19.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_head PF00063.21 CDJ37341.1 - 1.9e-25 89.2 0.0 7.4e-11 41.0 0.0 3.1 3 0 0 3 3 3 3 Myosin head (motor domain) Mannosyl_trans PF05007.13 CDJ37342.1 - 3e-35 122.4 34.4 6.7e-25 88.4 9.1 4.1 1 1 1 2 2 2 2 Mannosyltransferase (PIG-M) GT87 PF09594.10 CDJ37342.1 - 9.9e-05 22.2 5.6 9.9e-05 22.2 5.6 3.0 3 2 1 4 4 4 1 Glycosyltransferase family 87 Ammonium_transp PF00909.21 CDJ37342.1 - 0.1 11.3 5.2 0.54 8.9 0.8 2.2 2 0 0 2 2 2 0 Ammonium Transporter Family DUF4200 PF13863.6 CDJ37344.1 - 0.017 15.5 11.5 0.017 15.5 11.5 4.6 2 1 3 5 5 5 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.12 CDJ37344.1 - 3.5 7.7 11.3 16 5.6 5.0 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PBECR1 PF18809.1 CDJ37344.1 - 5.1 7.8 5.0 1.4 9.6 0.5 2.3 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 HHH_8 PF14716.6 CDJ37347.1 - 0.017 15.5 0.1 0.21 12.0 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain NopRA1 PF16201.5 CDJ37348.1 - 1e-06 28.5 0.7 4e-06 26.5 0.7 2.1 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 CDJ37348.1 - 0.039 13.3 1.1 0.16 11.3 0.1 2.5 3 0 0 3 3 3 0 Ribosome 60S biogenesis N-terminal ISP1_C PF18161.1 CDJ37349.1 - 3.9e-43 145.8 0.0 5e-43 145.5 0.0 1.1 1 0 0 1 1 1 1 ISP1 C-terminal ISP3_C PF18045.1 CDJ37349.1 - 1.9e-39 133.9 0.0 2.4e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 ISP3 C-terminal TFIIA PF03153.13 CDJ37351.1 - 0.074 13.0 20.5 0.085 12.8 20.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF840 PF05801.11 CDJ37351.1 - 0.3 11.2 0.1 0.3 11.2 0.1 1.7 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) CAP PF00188.26 CDJ37354.1 - 0.037 14.9 0.0 0.048 14.5 0.0 1.2 1 0 0 1 1 1 0 Cysteine-rich secretory protein family WD40 PF00400.32 CDJ37355.1 - 5.5e-14 52.3 22.2 0.00025 21.8 0.2 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 CDJ37355.1 - 0.025 13.3 0.2 2.1 6.9 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Adeno_PIX PF03955.14 CDJ37357.1 - 0.58 10.4 7.8 0.53 10.5 0.4 2.5 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) YfcL PF08891.11 CDJ37357.1 - 2.1 8.7 5.6 0.35 11.3 0.8 2.2 2 0 0 2 2 2 0 YfcL protein TMEM131_like PF12371.8 CDJ37358.1 - 1.5e-08 34.8 0.1 9.3e-08 32.2 0.0 2.3 2 0 0 2 2 2 1 Transmembrane protein 131-like ASH PF15780.5 CDJ37358.1 - 2.6e-06 27.6 0.0 1.7e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CDJ37358.1 - 0.0002 21.5 1.8 0.44 10.7 0.0 3.9 3 1 0 3 3 3 2 Flagellar-associated PapD-like Motile_Sperm PF00635.26 CDJ37358.1 - 0.15 12.0 0.0 0.49 10.3 0.0 1.9 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Cytomega_UL20A PF05984.12 CDJ37360.1 - 2.3 8.5 6.3 2.4 8.5 0.0 3.6 3 1 0 3 3 3 0 Cytomegalovirus UL20A protein Vps26 PF03643.15 CDJ37361.1 - 1.8e-106 355.2 1.3 2e-106 355.0 1.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CDJ37361.1 - 0.0026 17.9 1.3 4.2 7.4 0.0 3.3 2 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain CAP PF00188.26 CDJ37363.1 - 7.9e-12 46.1 0.3 1.7e-11 45.0 0.3 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PTS_2-RNA PF01885.16 CDJ37364.1 - 3.7e-58 196.6 0.0 8.4e-58 195.4 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family LMBR1 PF04791.16 CDJ37364.1 - 4.1 6.2 4.0 8.5 5.1 4.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Sdh5 PF03937.16 CDJ37365.1 - 0.0023 17.8 0.1 0.005 16.8 0.1 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase CSN8_PSD8_EIF3K PF10075.9 CDJ37366.1 - 5.4e-16 58.9 0.1 1.1e-15 57.9 0.1 1.4 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family SARAF PF06682.12 CDJ37367.1 - 0.0034 17.1 0.6 0.0034 17.1 0.6 4.7 4 1 0 4 4 4 1 SOCE-associated regulatory factor of calcium homoeostasis NIBRIN_BRCT_II PF16508.5 CDJ37367.1 - 1.6 9.1 7.2 0.81 10.0 1.5 2.9 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein PGA_cap PF09587.10 CDJ37367.1 - 6.3 6.2 9.9 0.18 11.2 0.7 3.1 4 0 0 4 4 4 0 Bacterial capsule synthesis protein PGA_cap AAA_8 PF12780.7 CDJ37368.1 - 1.3e-43 149.2 8.2 4.2e-33 114.8 0.0 4.2 3 1 0 3 3 3 2 P-loop containing dynein motor region D4 Dynein_heavy PF03028.15 CDJ37368.1 - 1.1e-33 115.8 0.0 1.1e-33 115.8 0.0 2.6 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CDJ37368.1 - 9.5e-28 97.2 11.2 1e-19 70.8 4.6 2.3 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor SPX PF03105.19 CDJ37368.1 - 0.0035 17.3 5.1 0.0035 17.3 5.1 3.4 3 1 0 3 3 3 1 SPX domain DUF1464 PF07318.12 CDJ37368.1 - 0.0056 15.9 0.1 0.0097 15.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1464) SUIM_assoc PF16619.5 CDJ37368.1 - 0.058 13.5 0.0 0.058 13.5 0.0 11.0 6 2 1 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 DEAD_2 PF06733.15 CDJ37370.1 - 1.4e-26 93.2 5.0 1.2e-21 77.1 0.0 3.2 2 1 0 2 2 2 2 DEAD_2 ResIII PF04851.15 CDJ37370.1 - 7.2e-07 29.4 0.4 0.0021 18.1 1.5 2.6 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ37370.1 - 0.00096 19.0 6.1 0.19 11.4 6.2 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 CDJ37370.1 - 0.0011 18.4 0.3 0.39 10.1 0.1 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.6 CDJ37370.1 - 0.052 13.8 2.3 22 5.3 2.7 2.9 2 1 0 2 2 2 0 AAA domain SPX PF03105.19 CDJ37370.1 - 0.12 12.3 4.6 0.054 13.4 2.3 1.6 2 0 0 2 2 2 0 SPX domain AAA_19 PF13245.6 CDJ37370.1 - 0.64 10.3 5.0 3.3 8.0 2.1 3.0 2 2 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.6 CDJ37371.1 - 1.8e-25 90.1 0.0 2.8e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Helicase C-terminal domain Chon_Sulph_att PF06566.11 CDJ37371.1 - 0.11 12.3 2.7 0.16 11.8 2.7 1.1 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain SARG PF15385.6 CDJ37371.1 - 3.3 6.8 8.2 4.3 6.4 8.2 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Diacid_rec PF05651.13 CDJ37372.1 - 3.6 7.3 6.4 0.6 9.8 1.1 2.3 2 0 0 2 2 2 0 Putative sugar diacid recognition RAP1 PF07218.11 CDJ37372.1 - 7.7 4.7 25.7 0.58 8.4 17.9 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) IQCJ-SCHIP1 PF15157.6 CDJ37373.1 - 0.13 12.1 2.4 0.13 12.1 2.4 1.1 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Corona_nucleoca PF00937.18 CDJ37373.1 - 0.86 8.6 7.5 1 8.4 7.5 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RAP1 PF07218.11 CDJ37373.1 - 3.4 5.8 8.3 3.5 5.8 8.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FHA PF00498.26 CDJ37374.1 - 6e-16 58.6 0.0 1.2e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ37374.1 - 3.9e-08 33.5 0.0 8.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RRM_1 PF00076.22 CDJ37375.1 - 9.3e-29 99.1 0.1 3.3e-15 55.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ37375.1 - 4.1e-09 36.4 0.4 0.0059 16.7 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 CDJ37375.1 - 0.051 13.6 0.0 8.9 6.4 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif DUF2339 PF10101.9 CDJ37377.1 - 0.32 9.5 0.9 0.4 9.2 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) PK_C PF02887.16 CDJ37377.1 - 0.47 10.7 4.7 1.6 9.0 4.4 1.8 1 1 1 2 2 2 0 Pyruvate kinase, alpha/beta domain PUF PF00806.19 CDJ37379.1 - 0.00097 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Pumilio-family RNA binding repeat AF-4 PF05110.13 CDJ37379.1 - 0.0028 15.9 13.0 0.0034 15.6 13.0 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein TPPK_C PF12555.8 CDJ37379.1 - 0.044 13.8 1.4 0.48 10.5 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal PNISR PF15996.5 CDJ37379.1 - 0.059 13.6 1.8 0.059 13.6 1.8 1.9 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR ORC_WH_C PF18137.1 CDJ37379.1 - 0.27 11.3 3.5 0.51 10.4 3.5 1.5 1 1 0 1 1 1 0 Origin recognition complex winged helix C-terminal KfrA_N PF11740.8 CDJ37379.1 - 0.34 11.6 9.9 0.82 10.4 6.1 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF1117 PF06547.12 CDJ37379.1 - 0.64 10.6 7.2 0.45 11.1 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) DUF1633 PF07794.11 CDJ37379.1 - 0.76 7.9 8.8 0.89 7.6 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) OAD_gamma PF04277.13 CDJ37379.1 - 0.88 10.2 6.1 14 6.3 1.6 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain SUZ PF12752.7 CDJ37379.1 - 1.1 10.0 9.4 3.5 8.5 2.9 2.3 2 0 0 2 2 2 0 SUZ domain GRIN_C PF15235.6 CDJ37379.1 - 1.9 8.7 6.1 0.36 11.1 2.3 1.6 2 0 0 2 2 2 0 G protein-regulated inducer of neurite outgrowth C-terminus Secretin_N_2 PF07655.13 CDJ37379.1 - 3.5 8.2 16.3 2.6 8.6 12.4 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain MID_MedPIWI PF18296.1 CDJ37379.1 - 9.8 5.9 16.2 38 4.0 16.2 1.8 1 1 0 1 1 1 0 MID domain of medPIWI PUF PF00806.19 CDJ37380.1 - 0.0054 16.4 0.0 6.7 6.6 0.0 4.0 4 0 0 4 4 4 1 Pumilio-family RNA binding repeat UPF0565 PF10561.9 CDJ37380.1 - 0.033 13.4 0.0 0.033 13.4 0.0 2.5 2 1 0 2 2 2 0 Uncharacterised protein family UPF0565 RabGAP-TBC PF00566.18 CDJ37381.1 - 2.5e-19 69.8 0.4 2.5e-19 69.8 0.4 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 CDJ37381.1 - 1.1e-12 47.8 0.0 7.7e-09 35.3 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37381.1 - 2.5e-07 30.2 0.0 3.9e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Rhodanese PF00581.20 CDJ37381.1 - 0.028 14.9 0.0 21 5.7 0.0 3.1 3 0 0 3 3 3 0 Rhodanese-like domain IL28A PF15177.6 CDJ37381.1 - 0.032 14.1 2.6 0.092 12.6 2.6 1.8 1 0 0 1 1 1 0 Interleukin-28A Kinase-like PF14531.6 CDJ37381.1 - 0.062 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-CCCH PF00642.24 CDJ37382.1 - 1.1e-10 41.2 13.7 2.1e-05 24.3 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ37382.1 - 4.7e-05 23.3 15.9 0.011 15.7 5.7 2.6 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 CDJ37382.1 - 5.2e-05 23.9 1.3 0.099 13.4 0.1 2.4 2 0 0 2 2 2 2 Torus domain RRM_1 PF00076.22 CDJ37382.1 - 7.4e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 CDJ37382.1 - 0.06 13.6 2.7 5.9 7.2 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 CDJ37382.1 - 1.5 8.7 16.2 3.2 7.7 6.6 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger PSII PF00421.19 CDJ37383.1 - 0.34 9.5 1.1 0.42 9.2 1.1 1.1 1 0 0 1 1 1 0 Photosystem II protein DUF2070 PF09843.9 CDJ37383.1 - 2.9 6.0 7.8 3.9 5.6 7.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SUIM_assoc PF16619.5 CDJ37384.1 - 7.4 6.7 0.0 0.54 10.4 9.7 24.2 21 5 0 22 22 22 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_L16 PF00252.18 CDJ37386.1 - 2e-21 76.4 0.1 2.7e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Cupin_8 PF13621.6 CDJ37387.1 - 3.9e-22 79.2 0.0 8.7e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CDJ37387.1 - 1.6e-20 73.7 0.1 3.5e-20 72.5 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 CDJ37387.1 - 0.00045 19.8 0.0 0.0016 18.0 0.0 1.9 2 1 0 2 2 2 1 Cupin superfamily protein GPI PF06560.11 CDJ37387.1 - 0.042 13.1 0.1 0.11 11.8 0.1 1.6 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) Cupin_2 PF07883.11 CDJ37387.1 - 0.057 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Cupin domain SR-25 PF10500.9 CDJ37387.1 - 2.5 7.7 17.9 0.11 12.1 8.6 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Mlo PF03094.15 CDJ37388.1 - 1.5e-07 30.2 3.2 1.7e-06 26.7 0.4 2.8 2 1 1 3 3 3 1 Mlo family EF-hand_1 PF00036.32 CDJ37388.1 - 0.067 12.8 0.0 8.4 6.2 0.1 2.7 2 0 0 2 2 2 0 EF hand Bac_export_2 PF01312.19 CDJ37388.1 - 4.2 6.5 7.7 3.4 6.8 3.0 2.2 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family UCH PF00443.29 CDJ37389.1 - 3.4e-66 223.4 0.0 1.9e-65 220.9 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ37389.1 - 1.9e-15 57.3 0.5 4.7e-10 39.6 0.0 3.8 4 1 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase SUIM_assoc PF16619.5 CDJ37389.1 - 8.2e-07 29.0 32.8 0.3 11.2 0.0 5.9 5 1 0 5 5 5 4 Unstructured region C-term to UIM in Ataxin3 PNISR PF15996.5 CDJ37389.1 - 5.8e-05 23.5 2.2 5.8e-05 23.5 2.2 3.2 4 0 0 4 4 4 1 Arginine/serine-rich protein PNISR TMEM51 PF15345.6 CDJ37389.1 - 0.3 10.9 0.0 0.3 10.9 0.0 2.9 4 0 0 4 4 4 0 Transmembrane protein 51 LCCL PF03815.19 CDJ37390.1 - 5.1e-56 186.8 0.0 2.1e-18 66.2 0.5 4.2 2 2 1 3 3 3 3 LCCL domain Rxt3 PF08642.10 CDJ37390.1 - 5.6e-09 36.8 0.0 7.2e-05 23.6 0.0 3.3 3 0 0 3 3 3 2 Histone deacetylation protein Rxt3 SRCR PF00530.18 CDJ37390.1 - 2e-07 31.5 1.5 0.026 15.0 0.0 2.7 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Laminin_G_3 PF13385.6 CDJ37390.1 - 4.4e-05 23.7 0.0 0.0025 17.9 0.0 2.3 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.17 CDJ37390.1 - 0.091 12.4 0.0 0.78 9.4 0.0 2.1 2 0 0 2 2 2 0 Pentaxin family LCCL PF03815.19 CDJ37391.1 - 2.3e-10 40.4 1.2 4.7e-10 39.5 1.2 1.6 1 0 0 1 1 1 1 LCCL domain PLAT PF01477.23 CDJ37391.1 - 2.5e-05 24.8 0.0 0.002 18.7 0.0 2.6 2 1 0 2 2 2 1 PLAT/LH2 domain DUF5372 PF17342.2 CDJ37391.1 - 0.13 12.7 0.5 5.4 7.5 0.0 2.9 3 1 0 3 3 3 0 Family of unknown function (DUF5372) Peptidase_M17_N PF02789.17 CDJ37391.1 - 2.6 7.9 7.3 1.9 8.3 0.5 2.6 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain DUF2722 PF10846.8 CDJ37393.1 - 0.00025 20.1 3.4 0.00025 20.1 3.4 4.5 3 1 0 4 4 4 1 Protein of unknown function (DUF2722) MAP65_ASE1 PF03999.12 CDJ37393.1 - 0.022 13.5 9.9 0.18 10.5 0.2 2.4 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) RskA PF10099.9 CDJ37393.1 - 0.024 14.9 1.9 0.024 14.9 1.9 8.0 2 2 2 4 4 4 0 Anti-sigma-K factor rskA Blt1 PF12754.7 CDJ37393.1 - 0.063 13.6 0.6 20 5.5 0.1 3.1 2 1 0 2 2 2 0 Blt1 N-terminal domain PurK_C PF17769.1 CDJ37394.1 - 0.2 11.4 0.3 0.36 10.6 0.3 1.4 1 0 0 1 1 1 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain AMP-binding PF00501.28 CDJ37395.1 - 8.2e-14 51.0 0.1 1.3e-11 43.8 0.1 2.1 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 CDJ37396.1 - 0.00034 19.3 0.0 0.00088 18.0 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme tRNA-synt_2b PF00587.25 CDJ37397.1 - 2e-20 73.5 0.0 4.3e-20 72.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CDJ37397.1 - 7.3e-06 26.0 0.1 1.2e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Anticodon binding domain Uma2 PF05685.12 CDJ37397.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative restriction endonuclease WD40 PF00400.32 CDJ37398.1 - 7.9e-12 45.5 5.7 0.034 15.0 0.3 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat DHC_N1 PF08385.12 CDJ37399.1 - 1.5e-49 169.1 13.8 4.5e-41 141.1 7.0 2.1 1 1 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 DUF4047 PF13256.6 CDJ37400.1 - 0.053 13.7 0.5 0.094 12.9 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) AAA_6 PF12774.7 CDJ37401.1 - 1.5e-143 477.7 0.0 2.6e-143 476.9 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ37401.1 - 1.9e-82 277.5 4.5 1.9e-82 277.5 4.5 3.4 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 CDJ37401.1 - 2.5e-08 34.0 0.0 1.8e-05 24.8 0.0 3.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ37401.1 - 1e-05 26.0 0.0 0.44 10.9 0.0 3.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_7 PF12775.7 CDJ37401.1 - 2.4e-05 24.0 0.4 0.025 14.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 CDJ37401.1 - 0.00013 22.2 0.2 0.16 12.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 CDJ37401.1 - 0.0005 19.5 0.0 0.0017 17.8 0.0 1.9 1 0 0 1 1 1 1 Bacterial TniB protein AAA_18 PF13238.6 CDJ37401.1 - 0.00073 20.1 1.6 0.32 11.6 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 CDJ37401.1 - 0.00075 19.3 1.4 0.52 10.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CDJ37401.1 - 0.0013 19.2 1.7 0.12 12.9 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CDJ37401.1 - 0.015 15.7 0.2 2 8.8 0.0 3.2 3 0 0 3 3 3 0 RNA helicase DUF853 PF05872.12 CDJ37401.1 - 0.026 13.1 3.2 0.87 8.1 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) TrwB_AAD_bind PF10412.9 CDJ37401.1 - 0.029 13.3 2.7 0.12 11.3 0.2 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 CDJ37401.1 - 0.042 13.2 0.1 1.1 8.6 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.6 CDJ37401.1 - 0.089 13.1 4.6 15 5.9 0.2 3.5 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 CDJ37401.1 - 0.098 11.7 0.3 0.52 9.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein BCL_N PF04714.13 CDJ37401.1 - 0.2 11.7 1.8 0.51 10.4 0.4 2.4 2 0 0 2 2 2 0 BCL7, N-terminal conserver region RHH_4 PF13467.6 CDJ37401.1 - 0.21 11.5 2.4 1.7 8.6 0.1 3.1 3 1 0 3 3 3 0 Ribbon-helix-helix domain AAA_28 PF13521.6 CDJ37401.1 - 0.23 11.7 4.4 13 6.0 0.1 3.3 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 CDJ37401.1 - 0.26 10.7 1.5 3.8 6.9 0.1 2.7 2 0 0 2 2 2 0 PhoH-like protein DUF4510 PF14971.6 CDJ37401.1 - 0.3 11.4 1.7 7.2 6.9 0.2 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4510) DUF2205 PF10224.9 CDJ37401.1 - 0.32 11.0 7.7 0.6 10.1 0.6 4.3 5 0 0 5 5 4 0 Short coiled-coil protein Arnt_C PF18583.1 CDJ37401.1 - 1.5 8.5 4.4 0.95 9.1 0.2 2.4 2 0 0 2 2 2 0 Aminoarabinose transferase C-terminal domain Seryl_tRNA_N PF02403.22 CDJ37401.1 - 3.3 8.0 10.3 3.4 7.9 0.5 4.4 3 1 0 4 4 3 0 Seryl-tRNA synthetase N-terminal domain AAA_7 PF12775.7 CDJ37402.1 - 1.3e-37 129.0 0.0 2.3e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 CDJ37402.1 - 1.6e-20 73.5 0.1 3.1e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDJ37402.1 - 1.9e-06 27.9 0.0 0.047 13.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ37402.1 - 0.015 15.5 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.7 CDJ37403.1 - 2.5e-88 295.8 0.0 7.8e-88 294.2 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDJ37403.1 - 3.4e-77 258.5 3.7 3.4e-77 258.5 3.7 2.8 2 0 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 CDJ37403.1 - 2.6e-46 158.2 14.6 3.4e-45 154.6 14.6 2.2 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 CDJ37403.1 - 0.031 14.5 0.7 0.11 12.7 0.7 2.1 1 0 0 1 1 1 0 AAA+ lid domain MPS2 PF17060.5 CDJ37403.1 - 0.04 13.2 12.2 0.014 14.7 3.2 2.3 2 0 0 2 2 2 0 Monopolar spindle protein 2 SKA1 PF07160.12 CDJ37403.1 - 6.3 6.6 26.6 0.62 9.9 2.2 3.3 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 Osmo_CC PF08946.10 CDJ37403.1 - 6.9 7.0 12.1 29 5.0 0.2 4.1 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Dynein_C PF18199.1 CDJ37404.1 - 6.4e-69 232.5 0.0 1.1e-68 231.8 0.0 1.3 1 1 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CDJ37404.1 - 3.2e-56 189.7 0.0 4.7e-56 189.1 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ37404.1 - 1.8e-11 44.2 0.4 5.7e-11 42.5 0.1 2.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Ran_BP1 PF00638.18 CDJ37406.1 - 2.8e-37 127.7 2.3 5.8e-37 126.7 2.3 1.5 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CDJ37406.1 - 0.041 13.8 2.4 0.15 12.0 2.4 1.8 1 1 0 1 1 1 0 WH1 domain NAD_binding_2 PF03446.15 CDJ37407.1 - 4.1e-46 157.0 1.2 6.4e-46 156.4 1.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CDJ37407.1 - 7.2e-32 110.2 0.0 1.6e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 CDJ37407.1 - 1.9e-06 28.3 0.0 3.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CDJ37407.1 - 2.7e-05 23.6 0.0 4.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CDJ37407.1 - 0.00012 22.1 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 CDJ37407.1 - 0.0046 16.5 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 CDJ37407.1 - 0.016 15.1 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 CDJ37407.1 - 0.043 13.5 0.1 0.088 12.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SPX PF03105.19 CDJ37408.1 - 0.023 14.6 12.1 0.029 14.3 12.1 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ37408.1 - 0.074 11.9 9.9 0.089 11.6 9.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ37408.1 - 0.089 11.3 8.6 0.11 11.1 8.6 1.1 1 0 0 1 1 1 0 Macoilin family SRP-alpha_N PF04086.13 CDJ37408.1 - 1.3 8.9 11.2 1.8 8.4 11.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PPP4R2 PF09184.11 CDJ37408.1 - 1.7 8.2 7.4 2.6 7.5 7.4 1.4 1 0 0 1 1 1 0 PPP4R2 CLP1_P PF16575.5 CDJ37410.1 - 0.0045 16.8 0.1 0.0072 16.1 0.1 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Ribosomal_60s PF00428.19 CDJ37410.1 - 2.4 8.8 21.3 2.9 8.6 1.8 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein CLP1_P PF16575.5 CDJ37411.1 - 7.8e-06 25.8 9.1 0.002 18.0 0.0 4.0 5 1 0 5 5 5 2 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF2722 PF10846.8 CDJ37411.1 - 0.21 10.5 48.4 0.049 12.6 4.3 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) DUF359 PF04019.12 CDJ37411.1 - 9.6 5.9 6.3 0.34 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF359) Ribosomal_L37 PF08561.10 CDJ37412.1 - 0.00097 19.7 3.7 0.0049 17.4 3.7 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 IMP2_N PF18590.1 CDJ37413.1 - 1.3e-19 70.5 0.0 2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain Pex14_N PF04695.13 CDJ37413.1 - 1 10.0 10.5 0.56 10.9 8.5 1.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1768 PF08719.11 CDJ37414.1 - 8e-15 55.4 0.0 1.7e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_1 PF00076.22 CDJ37414.1 - 1.5e-11 44.0 0.0 9.2e-11 41.4 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.26 CDJ37414.1 - 2.2e-08 34.3 0.0 6.6e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ37414.1 - 0.0006 20.1 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain His_Phos_1 PF00300.22 CDJ37415.1 - 7e-20 71.5 0.3 3.2e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AMPK1_CBM PF16561.5 CDJ37416.1 - 1.3e-06 28.5 0.0 3.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase SpoIIE PF07228.12 CDJ37416.1 - 3.8e-06 27.0 0.0 1.9e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) CS PF04969.16 CDJ37416.1 - 1.8e-05 25.7 0.1 2.8e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 CS domain PP2C PF00481.21 CDJ37416.1 - 9e-05 22.2 2.4 0.1 12.2 0.0 2.9 3 0 0 3 3 3 2 Protein phosphatase 2C Med3 PF11593.8 CDJ37416.1 - 0.00011 21.6 10.7 0.00011 21.6 10.7 4.7 3 1 1 5 5 5 1 Mediator complex subunit 3 fungal Pilosulin PF17499.2 CDJ37416.1 - 0.15 12.2 1.0 4.8 7.4 0.1 3.3 2 1 1 3 3 3 0 Ant venom peptides Apt1 PF10351.9 CDJ37416.1 - 0.4 9.5 2.2 0.75 8.6 2.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF936 PF06075.12 CDJ37417.1 - 0.44 9.4 22.0 0.67 8.8 22.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) FOG_N PF15888.5 CDJ37417.1 - 0.7 10.3 3.0 40 4.6 0.1 4.6 4 1 0 5 5 5 0 Folded gastrulation N-terminus Hamartin PF04388.12 CDJ37417.1 - 1.5 7.4 10.7 2.1 6.9 10.7 1.1 1 0 0 1 1 1 0 Hamartin protein CBM_14 PF01607.24 CDJ37417.1 - 1.5 9.0 0.0 1.5 9.0 0.0 6.7 6 2 2 8 8 8 0 Chitin binding Peritrophin-A domain Tme5_EGF_like PF09064.10 CDJ37417.1 - 5 7.1 15.0 9.7 6.2 0.8 6.3 8 0 0 8 8 8 0 Thrombomodulin like fifth domain, EGF-like Galactosyl_T PF01762.21 CDJ37418.1 - 1.2e-26 93.8 0.0 1.8e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase DUF1635 PF07795.11 CDJ37418.1 - 0.0081 16.1 5.5 0.0081 16.1 5.5 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1635) Conotoxin PF02950.17 CDJ37418.1 - 0.011 16.7 0.3 0.011 16.7 0.3 3.9 3 1 0 3 3 3 0 Conotoxin BUD22 PF09073.10 CDJ37418.1 - 0.085 12.2 6.9 0.14 11.5 6.9 1.3 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 CDJ37418.1 - 2.3 6.9 7.8 3.5 6.3 7.8 1.3 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 CDJ37418.1 - 4.4 5.7 9.4 7.4 4.9 9.4 1.4 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.13 CDJ37421.1 - 0.0012 18.9 21.7 0.0015 18.7 21.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ37421.1 - 0.35 10.9 1.5 0.41 10.7 1.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 CDJ37421.1 - 0.43 10.2 16.7 0.58 9.7 16.7 1.2 1 0 0 1 1 1 0 Spt20 family Draxin PF15550.6 CDJ37421.1 - 0.45 10.3 9.2 0.59 10.0 9.2 1.1 1 0 0 1 1 1 0 Draxin eIF-3_zeta PF05091.12 CDJ37421.1 - 2.2 7.2 7.8 2.7 6.9 7.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ37421.1 - 2.3 6.4 15.0 2.6 6.2 15.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ37421.1 - 5.4 4.0 10.2 6.3 3.8 10.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 CDJ37421.1 - 7.2 5.3 10.3 9 4.9 10.3 1.1 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.6 CDJ37421.1 - 9.2 6.1 18.6 16 5.4 18.6 1.3 1 0 0 1 1 1 0 Spore coat protein CotO TFIIA PF03153.13 CDJ37422.1 - 0.001 19.2 25.1 0.001 19.2 25.1 19.1 11 6 3 16 16 16 3 Transcription factor IIA, alpha/beta subunit Glyco_trans_1_2 PF13524.6 CDJ37422.1 - 0.0011 19.3 1.2 0.035 14.5 0.1 4.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 CPBP PF02517.16 CDJ37422.1 - 0.062 13.7 0.0 5.7 7.4 0.0 4.1 3 2 0 3 3 3 0 CPBP intramembrane metalloprotease tRNA-synt_1 PF00133.22 CDJ37423.1 - 3.4e-155 517.7 0.0 7.5e-96 321.7 0.0 3.2 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ37423.1 - 3.7e-24 85.4 0.0 1.7e-23 83.3 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ37423.1 - 1.6e-07 30.4 0.1 0.0058 15.4 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CDJ37423.1 - 0.00035 20.0 0.0 0.00059 19.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DNA_primase_S PF01896.19 CDJ37424.1 - 1.5e-38 132.6 0.0 3.3e-38 131.5 0.0 1.5 1 1 0 1 1 1 1 DNA primase small subunit Activator_LAG-3 PF11498.8 CDJ37424.1 - 9.3e-05 21.6 23.7 0.00015 20.9 23.7 1.4 1 0 0 1 1 1 1 Transcriptional activator LAG-3 DUF4667 PF15700.5 CDJ37424.1 - 0.0023 18.1 7.6 0.74 9.9 5.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4667) RskA PF10099.9 CDJ37424.1 - 0.018 15.4 19.3 0.1 12.9 19.3 2.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Chorion_2 PF03964.15 CDJ37424.1 - 0.042 14.7 2.5 0.042 14.7 2.5 4.2 3 1 1 4 4 2 0 Chorion family 2 SPT16 PF08644.11 CDJ37424.1 - 0.074 13.2 3.4 0.16 12.2 3.4 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) TFIIA PF03153.13 CDJ37424.1 - 0.14 12.2 24.8 0.18 11.7 24.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GT87 PF09594.10 CDJ37424.1 - 0.18 11.5 4.6 0.47 10.1 4.6 1.6 1 1 0 1 1 1 0 Glycosyltransferase family 87 Anp1 PF03452.14 CDJ37424.1 - 0.51 9.7 5.3 0.82 9.0 5.3 1.3 1 0 0 1 1 1 0 Anp1 DUF1645 PF07816.11 CDJ37424.1 - 0.59 10.7 14.9 1.1 9.8 5.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) TMEM247 PF15444.6 CDJ37424.1 - 0.91 9.5 9.7 0.46 10.5 7.6 1.6 1 1 0 1 1 1 0 Transmembrane protein 247 MPM1 PF17234.2 CDJ37424.1 - 6.5 7.0 10.8 15 5.8 10.8 1.5 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 TFIIA PF03153.13 CDJ37425.1 - 0.36 10.8 23.1 0.49 10.3 23.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 CDJ37425.1 - 3.7 6.5 9.0 0.16 11.1 1.6 2.0 2 0 0 2 2 2 0 Drosophila roughex protein Ndc1_Nup PF09531.10 CDJ37426.1 - 0.31 9.7 5.3 0.4 9.3 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup API5 PF05918.11 CDJ37426.1 - 0.63 8.8 5.1 0.82 8.4 5.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Androgen_recep PF02166.16 CDJ37428.1 - 0.0076 15.2 5.6 0.0076 15.2 5.6 5.0 4 1 1 5 5 5 1 Androgen receptor DUF4834 PF16118.5 CDJ37428.1 - 0.12 13.4 14.1 3.1 8.8 3.7 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Afi1 PF07792.12 CDJ37428.1 - 0.18 12.3 5.5 4.8 7.7 0.1 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Gti1_Pac2 PF09729.9 CDJ37428.1 - 0.24 11.5 5.0 0.92 9.6 0.9 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family MPM1 PF17234.2 CDJ37428.1 - 6.1 7.1 11.1 0.69 10.1 2.1 2.4 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 CPSF100_C PF13299.6 CDJ37428.1 - 7.2 6.8 8.1 10 6.2 0.5 2.6 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Apt1 PF10351.9 CDJ37428.1 - 8 5.2 12.8 0.25 10.1 4.7 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain Proteasome PF00227.26 CDJ37430.1 - 3.2e-29 101.8 0.0 5.4e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ37430.1 - 1.2e-11 44.1 0.1 2.8e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Peptidase_M20 PF01546.28 CDJ37430.1 - 0.13 12.0 0.0 0.17 11.5 0.0 1.3 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Gln-synt_C PF00120.24 CDJ37432.1 - 1.3e-90 303.9 0.0 4.2e-45 154.2 0.1 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CDJ37432.1 - 1.4e-19 69.6 0.0 2.4e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF202 PF02656.15 CDJ37432.1 - 2.4 8.6 0.0 2.4 8.6 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) SbcCD_C PF13558.6 CDJ37432.1 - 9.3 6.6 7.8 1.3 9.3 3.0 2.0 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit Clat_adaptor_s PF01217.20 CDJ37433.1 - 2.8e-43 147.3 2.2 3.1e-43 147.1 2.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CAC1F_C PF16885.5 CDJ37434.1 - 0.018 14.7 14.8 0.021 14.5 14.8 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term SID-1_RNA_chan PF13965.6 CDJ37434.1 - 0.04 12.3 4.7 0.043 12.2 4.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Exonuc_VII_L PF02601.15 CDJ37434.1 - 1.8 8.1 27.3 2.2 7.7 27.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Plasmodium_Vir PF05795.11 CDJ37434.1 - 2.1 7.7 12.2 2.4 7.5 12.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2722 PF10846.8 CDJ37435.1 - 0.0013 17.8 5.2 0.0015 17.6 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ37435.1 - 0.0019 17.0 10.2 0.0019 17.0 10.2 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SUIM_assoc PF16619.5 CDJ37435.1 - 0.0033 17.5 8.5 0.0033 17.5 8.5 3.0 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ37435.1 - 0.036 14.4 17.7 0.049 13.9 17.7 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ37435.1 - 0.088 12.4 15.4 0.16 11.6 15.4 1.4 1 0 0 1 1 1 0 Spt20 family PPR PF01535.20 CDJ37435.1 - 0.51 10.7 2.1 22 5.6 0.0 2.4 2 0 0 2 2 2 0 PPR repeat Phostensin_N PF13916.6 CDJ37435.1 - 0.98 9.8 8.5 1.4 9.3 4.6 2.4 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Med3 PF11593.8 CDJ37435.1 - 1.8 7.7 21.8 3 6.9 21.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF775 PF05603.12 CDJ37435.1 - 3.6 7.1 13.7 1.2 8.6 6.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF775) DUF719 PF05334.13 CDJ37435.1 - 7.4 6.7 11.2 21 5.2 11.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF719) PPV_E1_N PF00524.18 CDJ37436.1 - 0.74 10.2 9.3 0.43 11.0 5.8 2.3 1 1 1 2 2 2 0 E1 Protein, N terminal domain NUDIX PF00293.28 CDJ37439.1 - 0.0023 18.0 6.7 0.34 11.0 4.6 3.2 1 1 1 2 2 2 2 NUDIX domain TFIIA PF03153.13 CDJ37439.1 - 0.03 14.3 11.6 0.039 14.0 11.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BTP PF05232.12 CDJ37439.1 - 0.16 12.1 2.5 0.32 11.1 2.5 1.5 1 0 0 1 1 1 0 Chlorhexidine efflux transporter CNDH2_C PF16858.5 CDJ37439.1 - 0.2 11.5 7.2 0.29 11.0 7.2 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Ribosomal_60s PF00428.19 CDJ37439.1 - 8.2 7.1 21.4 9.1 6.9 1.2 3.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein AAA PF00004.29 CDJ37440.1 - 1.6e-23 83.6 0.1 1.6e-23 83.6 0.1 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CDJ37440.1 - 0.085 13.0 3.7 0.13 12.4 0.2 2.6 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) DUF572 PF04502.13 CDJ37440.1 - 8.1 6.0 11.2 11 5.5 11.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3395 PF11875.8 CDJ37441.1 - 1.6e-13 50.8 0.3 2.4e-13 50.2 0.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) SSTK-IP PF15836.5 CDJ37441.1 - 0.03 14.5 0.1 0.038 14.1 0.1 1.1 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein TMEM65 PF10507.9 CDJ37442.1 - 9e-23 80.3 0.2 9e-23 80.3 0.2 3.2 3 1 0 3 3 3 1 Transmembrane protein 65 EF-hand_5 PF13202.6 CDJ37442.1 - 1.9e-05 23.9 0.0 3.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 EF hand SPX PF03105.19 CDJ37442.1 - 0.00086 19.3 23.7 0.00086 19.3 23.7 2.2 2 0 0 2 2 2 1 SPX domain EF-hand_1 PF00036.32 CDJ37442.1 - 0.00099 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CDJ37442.1 - 0.0011 19.4 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ37442.1 - 0.0028 17.5 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain DUF4207 PF13904.6 CDJ37442.1 - 0.086 12.5 28.4 0.036 13.8 25.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4207) Hamartin PF04388.12 CDJ37442.1 - 4.1 6.0 43.8 6 5.4 43.8 1.2 1 0 0 1 1 1 0 Hamartin protein SOG2 PF10428.9 CDJ37442.1 - 7.6 5.6 51.0 2.2 7.4 3.7 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Topoisom_I PF01028.20 CDJ37443.1 - 7.7e-99 329.6 5.3 7.7e-99 329.6 5.3 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 CDJ37443.1 - 2.1e-56 190.8 0.5 2e-53 181.1 0.0 3.9 3 2 1 4 4 4 2 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 CDJ37443.1 - 1.4e-31 108.3 0.4 3.7e-31 106.9 0.4 1.8 1 0 0 1 1 1 1 C-terminal topoisomerase domain Syntaxin-6_N PF09177.11 CDJ37443.1 - 0.018 15.6 0.9 0.18 12.4 0.1 2.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 CDJ37443.1 - 9.4 6.3 8.2 9.1 6.3 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Yip1 PF04893.17 CDJ37444.1 - 3e-11 43.4 13.7 3.8e-11 43.0 13.7 1.1 1 0 0 1 1 1 1 Yip1 domain VGCC_beta4Aa_N PF12052.8 CDJ37444.1 - 0.34 11.1 5.3 0.54 10.4 5.3 1.3 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal RskA PF10099.9 CDJ37445.1 - 0.027 14.8 0.3 0.027 14.8 0.3 5.3 4 1 1 5 5 5 0 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ37445.1 - 0.042 13.9 0.3 0.042 13.9 0.3 5.0 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_L18A PF01775.17 CDJ37446.1 - 6.5e-38 129.5 0.1 8.4e-38 129.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A SR-25 PF10500.9 CDJ37447.1 - 0.27 10.8 6.4 0.082 12.5 3.0 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 CDJ37447.1 - 1.8 6.7 4.3 2.3 6.4 4.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PDEase_I PF00233.19 CDJ37448.1 - 2.9e-64 217.1 1.2 4e-64 216.6 1.2 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CDJ37448.1 - 0.029 14.6 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 HD domain RabGAP-TBC PF00566.18 CDJ37450.1 - 7.2e-46 156.6 3.1 1e-45 156.0 3.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4692 PF15763.5 CDJ37450.1 - 0.0064 17.0 1.0 0.0093 16.4 1.0 1.2 1 0 0 1 1 1 1 Regulator of human erythroid cell expansion (RHEX) SR-25 PF10500.9 CDJ37450.1 - 0.054 13.1 9.1 0.07 12.7 9.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 CDJ37450.1 - 0.15 10.4 2.6 0.18 10.2 1.9 1.4 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF755 PF05501.11 CDJ37450.1 - 0.56 10.5 12.1 0.88 9.9 12.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) IMUP PF15761.5 CDJ37450.1 - 0.97 10.2 7.7 1.4 9.6 7.7 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein Glyco_hydro_3_C PF01915.22 CDJ37451.1 - 6.7 6.6 8.1 7.3 6.5 8.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain DUF4366 PF14283.6 CDJ37451.1 - 7.3 6.6 9.9 8.5 6.4 9.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Prefoldin_2 PF01920.20 CDJ37452.1 - 1.5e-12 47.4 1.4 1.5e-12 47.4 1.4 2.5 2 1 1 3 3 3 1 Prefoldin subunit Ribosomal_L26 PF16906.5 CDJ37453.1 - 1.7e-33 114.9 3.5 2.1e-33 114.6 3.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CDJ37453.1 - 9.2e-08 31.8 2.2 2e-07 30.7 2.2 1.6 1 0 0 1 1 1 1 KOW motif VEG PF06257.11 CDJ37453.1 - 0.046 13.8 0.2 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 Biofilm formation stimulator VEG RabGAP-TBC PF00566.18 CDJ37454.1 - 2.5e-19 69.8 1.4 6.8e-15 55.3 0.2 2.8 2 1 1 3 3 3 2 Rab-GTPase-TBC domain GAGA_bind PF06217.12 CDJ37454.1 - 3.4 7.9 8.3 3.7 7.7 7.5 1.3 1 1 0 1 1 1 0 GAGA binding protein-like family Connexin PF00029.19 CDJ37455.1 - 0.0026 17.6 1.2 0.0064 16.3 1.2 1.7 1 0 0 1 1 1 1 Connexin U79_P34 PF03064.16 CDJ37455.1 - 0.034 13.5 10.4 0.077 12.3 10.4 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TRAP_alpha PF03896.16 CDJ37455.1 - 0.045 13.0 1.0 0.096 11.9 1.0 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cytomega_UL84 PF06284.11 CDJ37455.1 - 0.56 8.6 7.4 1.1 7.6 7.4 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein ALMT PF11744.8 CDJ37455.1 - 0.62 8.8 17.1 1.8 7.3 5.0 2.5 2 0 0 2 2 2 0 Aluminium activated malate transporter CRA PF06589.11 CDJ37455.1 - 1.3 9.1 9.5 0.047 13.8 1.7 2.4 2 1 0 2 2 2 0 Circumsporozoite-related antigen (CRA) O-antigen_lig PF13425.6 CDJ37455.1 - 2.1 7.0 8.0 0.66 8.7 0.4 2.6 3 0 0 3 3 3 0 O-antigen ligase like membrane protein DUF4471 PF14740.6 CDJ37455.1 - 3.2 6.9 10.0 0.9 8.7 0.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4471) RR_TM4-6 PF06459.12 CDJ37455.1 - 6.2 6.6 18.0 0.71 9.6 11.2 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Pkinase PF00069.25 CDJ37456.1 - 2.6e-33 115.5 0.4 8.4e-30 104.0 0.0 4.5 4 1 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37456.1 - 3.1e-16 59.4 0.0 3.1e-16 59.4 0.0 2.7 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ37456.1 - 5.1e-06 25.5 0.0 5.1e-06 25.5 0.0 4.7 2 1 0 3 3 3 1 Fungal protein kinase CD20 PF04103.15 CDJ37456.1 - 0.002 18.3 0.5 0.025 14.7 0.0 2.9 2 0 0 2 2 2 1 CD20-like family AIF_C PF14721.6 CDJ37456.1 - 0.015 15.7 9.4 0.015 15.7 9.4 5.6 5 1 0 5 5 5 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DcuC PF03606.15 CDJ37456.1 - 0.023 13.2 8.8 0.083 11.3 8.8 2.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier zf-CCCH PF00642.24 CDJ37457.1 - 3.4e-22 77.8 22.4 5e-08 32.7 1.4 4.5 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ37457.1 - 3.7e-22 77.6 26.8 1.8e-06 27.8 1.5 4.5 4 0 0 4 4 4 4 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ37457.1 - 1.3e-17 63.1 25.7 1.4e-05 24.8 1.4 4.3 4 0 0 4 4 4 4 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CDJ37457.1 - 1.4e-09 38.0 28.2 0.0024 18.3 2.2 4.3 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CDJ37457.1 - 0.00031 21.4 16.8 0.0054 17.4 0.7 8.5 4 2 4 9 9 9 4 Torus domain Hamartin PF04388.12 CDJ37457.1 - 1.4 7.5 44.4 0.036 12.7 15.9 2.2 2 0 0 2 2 2 0 Hamartin protein PTPlike_phytase PF14566.6 CDJ37459.1 - 0.077 13.1 1.8 0.099 12.8 1.8 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate PAT1 PF09770.9 CDJ37459.1 - 0.87 7.8 34.0 0.9 7.7 34.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.7 CDJ37459.1 - 1.6 6.8 15.8 1.8 6.6 15.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 CDJ37459.1 - 1.7 6.8 10.1 1.9 6.7 10.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SPX PF03105.19 CDJ37459.1 - 2.9 7.7 22.4 3.8 7.3 22.4 1.2 1 0 0 1 1 1 0 SPX domain MDM10 PF12519.8 CDJ37459.1 - 5.1 5.8 9.5 5.4 5.8 9.5 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Ribosomal_60s PF00428.19 CDJ37461.1 - 3.1e-23 82.1 11.1 3.9e-23 81.8 11.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein SurE PF01975.17 CDJ37461.1 - 0.079 12.7 0.3 0.25 11.1 0.3 1.7 2 0 0 2 2 2 0 Survival protein SurE Glyco_hydro_77 PF02446.17 CDJ37463.1 - 1.7e-51 175.6 0.1 3.6e-51 174.5 0.1 1.4 1 1 0 1 1 1 1 4-alpha-glucanotransferase Fez1 PF06818.15 CDJ37464.1 - 0.0042 17.6 5.4 0.0093 16.4 5.4 1.6 1 0 0 1 1 1 1 Fez1 PliI PF16743.5 CDJ37464.1 - 0.084 12.6 0.0 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 Periplasmic lysozyme inhibitor of I-type lysozyme TetR PF13972.6 CDJ37464.1 - 0.17 11.6 1.8 0.16 11.7 0.4 1.7 2 0 0 2 2 2 0 Bacterial transcriptional repressor MAD PF05557.13 CDJ37465.1 - 0.0037 15.7 3.1 0.0045 15.4 3.1 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein ATG16 PF08614.11 CDJ37465.1 - 0.0051 17.1 8.2 0.0084 16.3 6.9 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 CDJ37465.1 - 0.0096 15.9 6.6 0.0098 15.9 4.0 1.9 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding DUF2046 PF09755.9 CDJ37465.1 - 0.01 15.1 3.7 0.013 14.8 3.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) DUF1664 PF07889.12 CDJ37465.1 - 0.013 15.5 4.2 0.22 11.5 4.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 CDJ37465.1 - 0.015 14.2 4.0 0.021 13.7 4.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF713 PF05218.14 CDJ37465.1 - 0.018 14.8 0.9 0.027 14.2 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF713) HMMR_N PF15905.5 CDJ37465.1 - 0.021 14.3 3.2 0.028 13.9 3.2 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal KASH_CCD PF14662.6 CDJ37465.1 - 0.028 14.3 5.6 0.043 13.7 5.6 1.3 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Spectrin PF00435.21 CDJ37465.1 - 0.039 14.4 5.3 0.14 12.7 5.3 1.8 1 1 0 1 1 1 0 Spectrin repeat ADIP PF11559.8 CDJ37465.1 - 0.041 14.0 4.9 0.11 12.6 2.7 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 CDJ37465.1 - 0.05 13.2 2.1 0.057 13.0 2.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit BST2 PF16716.5 CDJ37465.1 - 0.051 14.2 7.9 0.1 13.2 5.8 2.0 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 CdvA PF18822.1 CDJ37465.1 - 0.053 13.4 4.4 0.37 10.6 4.4 2.1 1 1 0 1 1 1 0 CdvA-like coiled-coil domain FliD_N PF02465.18 CDJ37465.1 - 0.054 14.2 2.6 0.99 10.1 2.3 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Sigma54_CBD PF04963.13 CDJ37465.1 - 0.07 13.0 3.1 9.9 6.0 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 factor, core binding domain Cob_adeno_trans PF01923.18 CDJ37465.1 - 0.074 13.2 0.5 0.096 12.8 0.5 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Ead_Ea22 PF13935.6 CDJ37465.1 - 0.077 13.6 0.6 0.094 13.4 0.6 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein DUF4407 PF14362.6 CDJ37465.1 - 0.078 12.3 0.4 0.1 11.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) THDPS_N_2 PF14805.6 CDJ37465.1 - 0.13 12.5 0.5 0.95 9.7 0.2 2.3 1 1 1 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal UPF0242 PF06785.11 CDJ37465.1 - 0.19 11.8 10.3 2.9 7.9 9.3 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 CDJ37465.1 - 0.22 12.1 6.2 0.28 11.7 6.2 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1690 PF07956.11 CDJ37465.1 - 0.23 11.9 4.7 0.39 11.2 4.5 1.5 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Snapin_Pallidin PF14712.6 CDJ37465.1 - 0.26 11.8 9.2 0.37 11.2 1.8 2.2 1 1 1 2 2 2 0 Snapin/Pallidin TMPIT PF07851.13 CDJ37465.1 - 0.46 9.7 2.6 0.57 9.4 2.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Med9 PF07544.13 CDJ37465.1 - 0.56 10.3 6.4 0.97 9.6 4.0 2.4 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.9 CDJ37465.1 - 0.76 10.1 5.1 17 5.8 0.1 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 CDJ37465.1 - 0.97 9.6 4.7 1.9 8.7 4.7 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.11 CDJ37465.1 - 1.7 8.5 6.5 7.9 6.3 2.7 1.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DivIC PF04977.15 CDJ37465.1 - 3.6 7.4 8.9 9.4 6.1 0.7 2.9 1 1 2 3 3 3 0 Septum formation initiator LPP PF04728.13 CDJ37465.1 - 6.6 7.2 7.3 9.5 6.7 0.3 2.9 2 1 0 2 2 2 0 Lipoprotein leucine-zipper SlyX PF04102.12 CDJ37465.1 - 7.9 7.2 11.7 3.3 8.4 1.0 2.9 1 1 2 3 3 3 0 SlyX WD40 PF00400.32 CDJ37466.1 - 6e-33 112.4 26.2 0.00021 22.0 1.7 11.3 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ37466.1 - 1.2e-16 60.8 0.0 0.0054 17.0 0.0 7.5 4 2 5 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDJ37466.1 - 0.00029 20.8 0.0 0.023 14.6 0.0 3.5 4 2 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 CDJ37466.1 - 0.0013 19.2 5.2 19 5.9 0.0 6.7 7 0 0 7 7 7 1 PQQ-like domain Ge1_WD40 PF16529.5 CDJ37466.1 - 0.0033 16.4 0.0 11 4.9 0.0 4.2 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NHL PF01436.21 CDJ37466.1 - 1.7 8.8 3.9 1.7 8.9 0.1 3.0 4 0 0 4 4 4 0 NHL repeat ASH PF15780.5 CDJ37468.1 - 1.2e-06 28.7 0.0 0.0021 18.2 0.0 2.8 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF2870 PF11069.8 CDJ37468.1 - 0.047 14.1 0.1 0.12 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) TPR_2 PF07719.17 CDJ37471.1 - 9.3e-13 47.2 17.8 0.037 14.1 0.9 6.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ37471.1 - 8.8e-09 35.7 10.7 0.015 15.8 7.8 4.7 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ37471.1 - 2e-08 34.4 24.0 0.00061 20.4 2.1 6.7 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ37471.1 - 1.7e-07 30.7 8.7 0.097 12.5 0.3 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ37471.1 - 7e-06 26.2 7.3 0.078 13.2 1.1 4.5 1 1 4 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CDJ37471.1 - 7.9e-06 25.7 11.0 0.029 14.6 0.6 6.0 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ37471.1 - 8.2e-06 26.0 20.0 0.01 16.1 0.1 5.5 3 2 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ37471.1 - 1.6e-05 25.2 16.0 0.14 12.9 1.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ37471.1 - 3.5e-05 23.9 0.3 0.039 14.3 0.0 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ37471.1 - 3.7e-05 24.3 16.1 0.00073 20.1 7.0 6.3 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ37471.1 - 0.0003 20.4 2.0 1.1 9.1 0.0 5.3 5 1 1 6 6 6 1 TPR repeat TPR_15 PF13429.6 CDJ37471.1 - 0.00084 18.6 1.2 0.00084 18.6 1.2 2.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ37471.1 - 0.0011 19.1 15.5 0.0032 17.6 2.6 4.7 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ37471.1 - 0.0014 18.5 9.5 1.9 8.7 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TAF1_subA PF14929.6 CDJ37471.1 - 0.0054 16.2 0.3 0.68 9.3 0.0 2.2 2 0 0 2 2 2 1 TAF RNA Polymerase I subunit A HrpB1_HrpK PF09613.10 CDJ37471.1 - 0.01 15.4 2.2 0.68 9.6 0.5 3.1 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_3 PF07720.12 CDJ37471.1 - 0.041 13.9 1.0 0.45 10.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3808 PF10300.9 CDJ37471.1 - 0.058 12.1 0.1 0.15 10.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) TPR_10 PF13374.6 CDJ37471.1 - 0.34 10.9 7.8 9.8 6.2 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 CDJ37471.1 - 0.71 10.2 8.6 1.6 9.1 0.5 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat SR-25 PF10500.9 CDJ37472.1 - 0.0076 15.9 14.4 0.0087 15.7 14.4 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Spem1 PF15670.5 CDJ37472.1 - 5 6.6 13.4 5.5 6.5 13.4 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 SNF2_N PF00176.23 CDJ37474.1 - 5.1e-42 143.8 12.3 1.2e-41 142.7 12.3 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 CDJ37474.1 - 4.6e-28 97.5 0.5 4.6e-28 97.5 0.5 3.0 2 1 0 2 2 1 1 SLIDE Helicase_C PF00271.31 CDJ37474.1 - 4.3e-18 65.7 2.8 6.5e-18 65.1 0.0 2.8 4 0 0 4 4 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ37474.1 - 6e-05 23.1 6.1 6e-05 23.1 6.1 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 CDJ37474.1 - 9.4e-05 22.5 0.1 0.14 12.3 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF2052 PF09747.9 CDJ37474.1 - 0.0059 16.8 11.5 0.0059 16.8 11.5 2.6 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) DEAD PF00270.29 CDJ37474.1 - 0.0084 15.9 1.0 0.031 14.0 1.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase DDHD PF02862.17 CDJ37474.1 - 0.012 15.7 13.5 0.064 13.4 4.9 2.7 2 0 0 2 2 2 0 DDHD domain AAA_11 PF13086.6 CDJ37474.1 - 0.09 12.6 24.5 0.017 14.9 12.4 2.7 2 0 0 2 2 2 0 AAA domain RR_TM4-6 PF06459.12 CDJ37474.1 - 0.19 11.5 29.3 0.23 11.2 2.4 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.13 CDJ37474.1 - 0.47 10.2 24.5 0.26 11.0 13.9 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Spt20 PF12090.8 CDJ37474.1 - 0.92 9.1 41.2 4.3 6.9 2.3 2.7 2 0 0 2 2 2 0 Spt20 family EPL1 PF10513.9 CDJ37474.1 - 1.3 9.4 18.5 2.5 8.5 12.5 2.7 2 0 0 2 2 2 0 Enhancer of polycomb-like Neur_chan_memb PF02932.16 CDJ37474.1 - 3.9 7.5 22.3 3 7.8 12.8 2.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TMEM51 PF15345.6 CDJ37474.1 - 5.1 6.9 21.9 1.1 9.1 9.5 3.5 3 0 0 3 3 3 0 Transmembrane protein 51 PNISR PF15996.5 CDJ37474.1 - 5.7 7.2 33.1 2.7 8.2 20.3 3.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Ctr PF04145.15 CDJ37474.1 - 6.3 7.4 12.8 3.8 8.1 4.4 3.0 2 0 0 2 2 2 0 Ctr copper transporter family Velvet PF11754.8 CDJ37474.1 - 6.7 6.6 22.4 0.53 10.2 8.8 2.8 3 0 0 3 3 3 0 Velvet factor RPN2_C PF18004.1 CDJ37474.1 - 7.9 6.4 26.1 6.3 6.7 17.6 2.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Presenilin PF01080.17 CDJ37474.1 - 9.3 4.9 30.4 1.2 7.9 18.9 2.2 2 0 0 2 2 2 0 Presenilin UPF0093 PF03653.13 CDJ37476.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) TFIIF_alpha PF05793.12 CDJ37477.1 - 0.00026 19.7 17.9 0.00039 19.1 17.9 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF755 PF05501.11 CDJ37477.1 - 0.0099 16.2 41.7 0.0099 16.2 41.7 2.6 3 0 0 3 3 2 1 Domain of unknown function (DUF755) FAM60A PF15396.6 CDJ37477.1 - 0.22 11.5 19.2 0.39 10.7 19.2 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF2151 PF10221.9 CDJ37477.1 - 0.37 9.3 11.0 0.4 9.2 11.0 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4603 PF15376.6 CDJ37477.1 - 0.69 7.2 21.9 0.78 7.1 21.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Menin PF05053.13 CDJ37477.1 - 1.5 7.1 12.0 1.6 7.0 12.0 1.1 1 0 0 1 1 1 0 Menin GREB1 PF15782.5 CDJ37477.1 - 1.5 5.9 13.3 1.5 5.9 13.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zip PF02535.22 CDJ37477.1 - 1.8 7.7 8.8 2 7.6 8.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 CDJ37477.1 - 2.5 6.9 20.7 2.9 6.6 20.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4692 PF15763.5 CDJ37477.1 - 6 7.3 13.8 9.7 6.6 13.8 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) SpoIIIAH PF12685.7 CDJ37477.1 - 6.6 6.5 18.2 11 5.8 18.2 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein FancD2 PF14631.6 CDJ37477.1 - 8 3.7 13.6 10 3.3 13.6 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease BT1 PF03092.16 CDJ37479.1 - 0.074 11.3 3.2 1.8 6.7 0.5 3.2 2 0 0 2 2 2 0 BT1 family DUF3801 PF12687.7 CDJ37481.1 - 0.042 13.9 9.3 0.052 13.6 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Sporozoite_P67 PF05642.11 CDJ37481.1 - 0.16 10.0 3.3 0.17 9.9 3.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4865 PF16157.5 CDJ37481.1 - 0.69 9.9 4.9 0.2 11.6 2.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4865) HMG_box PF00505.19 CDJ37482.1 - 1.7e-12 47.6 2.4 5.3e-12 46.0 2.4 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ37482.1 - 0.00018 22.1 1.6 0.00018 22.1 1.6 2.9 1 1 1 2 2 2 1 HMG-box domain SET PF00856.28 CDJ37482.1 - 0.094 13.1 0.0 0.094 13.1 0.0 4.9 3 3 0 3 3 3 0 SET domain ubiquitin PF00240.23 CDJ37483.1 - 2.1e-104 341.4 9.7 5.7e-34 115.7 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 CDJ37483.1 - 1.1e-49 166.1 11.5 7.5e-16 57.7 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ37483.1 - 4.4e-20 71.9 2.9 9.5e-05 22.8 0.1 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ37483.1 - 7.2e-13 48.3 1.2 0.014 15.3 0.0 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ37483.1 - 1.6e-11 44.2 0.7 0.062 13.4 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CDJ37483.1 - 2.1e-11 44.0 1.6 0.044 14.1 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin-like domain DUF2407 PF10302.9 CDJ37483.1 - 1.5e-09 38.3 0.1 0.26 11.9 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CDJ37483.1 - 3.3e-06 27.0 0.0 2.3 8.0 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 CDJ37483.1 - 7.6e-06 25.9 13.9 17 5.6 0.0 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF2870 PF11069.8 CDJ37483.1 - 0.00024 21.4 0.1 20 5.6 0.0 3.8 3 3 0 3 3 3 0 Protein of unknown function (DUF2870) UDP-g_GGTase PF06427.11 CDJ37483.1 - 0.002 18.2 1.3 4.2 7.5 0.0 3.1 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 CDJ37483.1 - 0.0067 15.9 0.0 14 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) TmoB PF06234.12 CDJ37483.1 - 0.0094 16.0 2.3 35 4.6 0.1 3.7 3 3 0 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) DUF3861 PF12977.7 CDJ37483.1 - 0.02 15.0 0.2 60 3.9 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) FlgD_ig PF13860.6 CDJ37483.1 - 0.026 14.4 2.8 39 4.2 0.1 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain RBD PF02196.15 CDJ37483.1 - 0.034 14.2 0.0 80 3.4 0.0 3.3 3 0 0 3 3 3 0 Raf-like Ras-binding domain ProRS-C_2 PF09181.10 CDJ37483.1 - 0.046 13.9 0.7 78 3.5 0.0 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal ORF11CD3 PF10549.9 CDJ37483.1 - 0.06 13.5 0.0 62 3.8 0.0 3.7 3 0 0 3 3 3 0 ORF11CD3 domain Big_7 PF17957.1 CDJ37483.1 - 0.13 13.0 0.0 1.7e+02 3.1 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig domain TraK PF06586.11 CDJ37483.1 - 0.17 11.5 0.1 83 2.8 0.0 3.0 3 0 0 3 3 3 0 TraK protein DMA PF03474.14 CDJ37483.1 - 0.43 10.2 1.7 1.1e+02 2.5 0.0 3.3 3 0 0 3 3 3 0 DMRTA motif MS_channel PF00924.18 CDJ37484.1 - 1.4e-09 37.8 5.0 5.5e-09 35.9 5.0 2.0 1 1 0 1 1 1 1 Mechanosensitive ion channel Secretin_N PF03958.17 CDJ37484.1 - 9 6.8 10.0 0.73 10.3 1.3 3.8 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain TIM PF00121.18 CDJ37485.1 - 5.1e-87 291.3 0.2 5.7e-87 291.1 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase PKS_DE PF18369.1 CDJ37485.1 - 0.046 14.3 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain Kinesin PF00225.23 CDJ37486.1 - 3.5e-80 269.4 0.4 3.7e-57 193.7 0.0 4.1 3 1 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ37486.1 - 6.1e-20 71.7 0.1 7.6e-19 68.1 0.0 2.8 2 1 0 2 2 2 1 Microtubule binding IF-2 PF11987.8 CDJ37487.1 - 6e-20 71.3 0.8 1e-19 70.6 0.8 1.4 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CDJ37487.1 - 4.1e-10 39.9 0.5 7.6e-10 39.0 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RNA_helicase PF00910.22 CDJ37488.1 - 0.00038 20.8 0.0 0.0013 19.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Spt20 PF12090.8 CDJ37488.1 - 0.0024 17.5 23.2 0.0024 17.5 23.2 4.2 3 1 0 3 3 3 2 Spt20 family DUF2722 PF10846.8 CDJ37488.1 - 0.0047 15.9 19.3 0.0047 15.9 19.3 4.1 3 1 0 3 3 3 2 Protein of unknown function (DUF2722) AAA_22 PF13401.6 CDJ37488.1 - 0.042 14.1 0.1 0.042 14.1 0.1 3.6 3 1 0 4 4 4 0 AAA domain MMR_HSR1 PF01926.23 CDJ37488.1 - 0.055 13.6 1.7 0.08 13.0 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.20 CDJ37488.1 - 0.54 9.4 15.1 0.04 13.1 4.6 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.23 CDJ37488.1 - 3.5 7.7 14.1 11 6.0 0.0 3.4 3 0 0 3 3 3 0 Dynamin family EOS1 PF12326.8 CDJ37488.1 - 6.1 6.7 17.0 2.3 8.1 11.1 2.7 2 1 0 2 2 2 0 N-glycosylation protein CSG2 PF16965.5 CDJ37488.1 - 8.1 5.3 15.1 0.43 9.5 3.0 2.5 3 0 0 3 3 3 0 Ceramide synthase regulator DUF3180 PF11377.8 CDJ37489.1 - 0.17 12.0 12.1 0.22 11.7 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) DUF5129 PF17173.4 CDJ37489.1 - 0.18 10.9 4.5 0.23 10.5 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) IMUP PF15761.5 CDJ37489.1 - 2.2 9.0 10.5 6.3 7.5 1.2 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF1690 PF07956.11 CDJ37490.1 - 0.0066 16.9 4.4 0.0066 16.9 4.4 3.9 2 1 0 3 3 3 1 Protein of Unknown function (DUF1690) DUF4404 PF14357.6 CDJ37490.1 - 0.072 13.7 9.0 2.3 8.9 8.8 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) AMP-binding PF00501.28 CDJ37491.1 - 2.2e-09 36.4 5.6 2.2e-06 26.6 0.0 2.9 3 0 0 3 3 3 2 AMP-binding enzyme GRDP-like PF07173.12 CDJ37491.1 - 0.24 12.1 0.1 0.24 12.1 0.1 3.2 2 1 0 2 2 2 0 Glycine-rich domain-containing protein-like DUF2722 PF10846.8 CDJ37492.1 - 0.0014 17.7 8.1 0.0014 17.7 8.1 8.5 8 2 0 8 8 8 2 Protein of unknown function (DUF2722) Polysacc_synt_2 PF02719.15 CDJ37492.1 - 6.8 5.7 5.9 0.97 8.5 0.5 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PNP_UDP_1 PF01048.20 CDJ37493.1 - 2.5e-32 112.0 0.0 3.2e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily F5_F8_type_C PF00754.25 CDJ37494.1 - 3.1e-12 46.7 0.0 1.5e-08 34.8 0.0 3.5 3 0 0 3 3 3 2 F5/8 type C domain LCCL PF03815.19 CDJ37494.1 - 4.8e-11 42.6 0.1 1.4e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 LCCL domain Laminin_N PF00055.17 CDJ37494.1 - 0.097 12.3 0.0 0.35 10.4 0.0 1.8 1 1 1 2 2 2 0 Laminin N-terminal (Domain VI) Rxt3 PF08642.10 CDJ37494.1 - 0.21 12.4 0.0 0.55 11.0 0.0 1.7 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Mago_nashi PF02792.14 CDJ37495.1 - 2.6e-75 251.3 0.4 2.9e-75 251.1 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein Histone PF00125.24 CDJ37496.1 - 2e-20 73.5 0.4 2.4e-20 73.2 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDJ37496.1 - 5.8e-05 23.3 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CDJ37496.1 - 0.00082 19.8 0.0 0.0012 19.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A SPX PF03105.19 CDJ37497.1 - 0.086 12.8 12.3 0.14 12.1 12.3 1.3 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 CDJ37497.1 - 2.9 7.0 20.0 5.5 6.1 20.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Biotin_lipoyl PF00364.22 CDJ37498.1 - 1.8e-29 101.3 0.5 5.3e-18 64.6 0.0 2.6 3 0 0 3 3 3 2 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CDJ37498.1 - 0.0012 18.6 5.7 0.37 10.7 0.0 4.0 3 1 1 4 4 4 2 Biotin-lipoyl like GCV_H PF01597.19 CDJ37498.1 - 0.0017 18.2 0.1 0.98 9.3 0.0 2.7 2 0 0 2 2 2 2 Glycine cleavage H-protein Virul_Fac PF10139.9 CDJ37498.1 - 0.14 10.3 4.0 0.2 9.9 4.0 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor SUIM_assoc PF16619.5 CDJ37499.1 - 0.003 17.6 0.2 0.003 17.6 0.2 2.2 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ37499.1 - 0.11 12.1 4.5 0.2 11.2 4.5 1.4 1 0 0 1 1 1 0 Spt20 family XAP5 PF04921.14 CDJ37500.1 - 1.8e-64 217.9 15.8 1.8e-64 217.9 15.8 2.8 1 1 1 2 2 2 1 XAP5, circadian clock regulator DPM3 PF08285.11 CDJ37500.1 - 0.0085 16.3 6.0 0.5 10.6 0.2 2.6 2 0 0 2 2 2 2 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Kdo PF06293.14 CDJ37501.1 - 0.072 12.4 0.2 0.076 12.4 0.2 1.0 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PI3_PI4_kinase PF00454.27 CDJ37502.1 - 8.9e-33 114.1 0.2 1.1e-23 84.4 0.2 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase V_ATPase_I PF01496.19 CDJ37502.1 - 1.6e-05 23.1 5.3 2.3e-05 22.6 5.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ37502.1 - 0.015 15.1 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 CDJ37502.1 - 0.025 13.6 0.7 0.043 12.8 0.7 1.4 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 CDJ37502.1 - 0.033 14.2 0.9 0.049 13.7 0.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.17 CDJ37502.1 - 0.035 14.3 0.1 0.05 13.8 0.1 1.4 1 0 0 1 1 1 0 DDHD domain DUF4135 PF13575.6 CDJ37502.1 - 0.065 12.5 2.4 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) EPL1 PF10513.9 CDJ37502.1 - 0.072 13.5 3.0 0.11 12.9 3.0 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like CCDC53 PF10152.9 CDJ37502.1 - 0.089 13.2 5.0 0.19 12.2 5.0 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex TRAP_alpha PF03896.16 CDJ37502.1 - 0.094 11.9 0.2 0.17 11.1 0.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MMR1 PF08505.10 CDJ37502.1 - 0.21 11.9 10.8 4.3 7.6 13.1 1.8 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein XK-related PF09815.9 CDJ37502.1 - 0.26 10.3 2.4 0.4 9.7 2.4 1.2 1 0 0 1 1 1 0 XK-related protein Presenilin PF01080.17 CDJ37502.1 - 0.39 9.4 8.5 0.59 8.8 8.5 1.2 1 0 0 1 1 1 0 Presenilin DUF4148 PF13663.6 CDJ37502.1 - 0.5 10.6 6.3 0.53 10.5 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) EMC3_TMCO1 PF01956.16 CDJ37502.1 - 0.51 10.0 3.0 1.2 8.9 3.0 1.6 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like eIF-3_zeta PF05091.12 CDJ37502.1 - 2.2 7.2 13.1 3.1 6.7 13.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ37502.1 - 4.4 5.5 16.9 5.9 5.0 16.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2722 PF10846.8 CDJ37502.1 - 4.8 6.0 22.4 0.0086 15.1 6.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ37502.1 - 5.5 6.9 29.5 8.4 6.3 29.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Orf78 PF06024.12 CDJ37502.1 - 6.4 7.1 6.4 30 5.0 2.6 2.4 2 0 0 2 2 2 0 Orf78 (ac78) HemY_N PF07219.13 CDJ37502.1 - 7.1 6.9 10.7 0.49 10.6 3.6 2.6 2 1 0 2 2 2 0 HemY protein N-terminus PPL5 PF18168.1 CDJ37503.1 - 0.0011 18.4 3.0 0.0011 18.4 3.0 1.6 2 0 0 2 2 2 1 Prim-pol family 5 eIF-3_zeta PF05091.12 CDJ37503.1 - 0.14 11.1 11.6 0.18 10.8 11.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EPL1 PF10513.9 CDJ37503.1 - 0.29 11.5 8.4 0.43 11.0 8.4 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like FemAB PF02388.16 CDJ37503.1 - 0.3 9.9 13.8 0.49 9.2 13.8 1.3 1 0 0 1 1 1 0 FemAB family MMR1 PF08505.10 CDJ37503.1 - 0.36 11.1 11.7 0.45 10.8 11.7 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4834 PF16118.5 CDJ37503.1 - 0.41 11.7 9.2 0.89 10.6 9.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ37503.1 - 0.42 9.3 8.9 0.56 8.9 8.9 1.2 1 0 0 1 1 1 0 Presenilin GNT-I PF03071.15 CDJ37503.1 - 0.46 9.2 9.7 0.63 8.7 9.7 1.1 1 0 0 1 1 1 0 GNT-I family DUF4638 PF15472.6 CDJ37503.1 - 0.7 9.6 11.0 1 9.1 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Ribosomal_S2 PF00318.20 CDJ37503.1 - 0.72 9.0 7.1 1.1 8.4 7.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 SpoIIP PF07454.11 CDJ37503.1 - 0.8 9.1 9.6 1.1 8.6 9.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CLN3 PF02487.17 CDJ37503.1 - 0.91 8.5 7.3 1.3 8.0 7.3 1.3 1 0 0 1 1 1 0 CLN3 protein TERB2 PF15101.6 CDJ37503.1 - 0.91 9.5 12.9 1.5 8.9 12.9 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EIIBC-GUT_N PF03612.14 CDJ37503.1 - 0.91 9.2 10.8 2.3 7.9 10.5 1.7 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus HCO3_cotransp PF00955.21 CDJ37503.1 - 0.98 8.2 3.5 1.7 7.4 3.5 1.3 1 0 0 1 1 1 0 HCO3- transporter family Gti1_Pac2 PF09729.9 CDJ37503.1 - 1.4 9.0 8.5 2.1 8.4 8.5 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4366 PF14283.6 CDJ37503.1 - 1.6 8.7 9.7 0.72 9.9 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) CPSF100_C PF13299.6 CDJ37503.1 - 1.8 8.7 11.0 0.5 10.5 6.7 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CSG2 PF16965.5 CDJ37503.1 - 3.1 6.7 4.7 4.4 6.2 4.7 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Orf78 PF06024.12 CDJ37503.1 - 3.2 8.1 8.5 9.7 6.6 7.1 2.1 2 0 0 2 2 2 0 Orf78 (ac78) DUF1779 PF08680.10 CDJ37503.1 - 3.2 7.9 12.1 4.5 7.4 12.1 1.2 1 0 0 1 1 1 0 TATA-box binding DUF5095 PF17016.5 CDJ37503.1 - 3.5 7.3 9.5 5.1 6.7 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) ALMT PF11744.8 CDJ37503.1 - 3.7 6.3 11.4 5.3 5.8 11.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CCDC53 PF10152.9 CDJ37503.1 - 6.1 7.2 14.8 12 6.2 9.4 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex FliP PF00813.20 CDJ37503.1 - 8 6.3 8.5 6.1 6.7 6.8 1.7 2 0 0 2 2 2 0 FliP family AviRa PF11599.8 CDJ37503.1 - 8.8 5.7 11.2 18 4.7 11.2 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa IMP2_N PF18590.1 CDJ37504.1 - 1.8e-16 60.4 0.1 3.5e-16 59.5 0.1 1.5 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain EPL1 PF10513.9 CDJ37504.1 - 0.014 15.7 4.9 0.018 15.5 4.9 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like TFIIA PF03153.13 CDJ37504.1 - 0.015 15.3 19.6 0.015 15.3 19.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 CDJ37504.1 - 0.036 12.4 2.8 0.036 12.4 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 CDJ37504.1 - 0.18 11.2 7.3 0.18 11.2 7.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Senescence_reg PF04520.13 CDJ37504.1 - 0.2 12.5 8.0 0.26 12.1 8.0 1.2 1 0 0 1 1 1 0 Senescence regulator Presenilin PF01080.17 CDJ37504.1 - 0.54 9.0 8.3 0.51 9.0 8.3 1.1 1 0 0 1 1 1 0 Presenilin SprA-related PF12118.8 CDJ37504.1 - 1.8 7.6 16.3 2.4 7.2 16.3 1.3 1 0 0 1 1 1 0 SprA-related family SPATA3 PF15662.5 CDJ37504.1 - 2.6 8.6 11.4 3.6 8.2 11.4 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family HGTP_anticodon2 PF12745.7 CDJ37504.1 - 3.3 7.1 9.4 5.1 6.5 9.4 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Ndc1_Nup PF09531.10 CDJ37504.1 - 4.2 6.0 6.9 4.4 5.9 6.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MDM10 PF12519.8 CDJ37504.1 - 4.4 6.1 5.6 4.4 6.1 5.6 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PAT1 PF09770.9 CDJ37504.1 - 5.3 5.2 17.5 5.6 5.1 17.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ37504.1 - 5.6 6.7 11.3 7.9 6.2 11.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 CDJ37504.1 - 6.2 6.5 6.7 11 5.7 6.7 1.4 1 0 0 1 1 1 0 FAM176 family DUF3464 PF11947.8 CDJ37504.1 - 7 6.4 13.7 14 5.4 13.7 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4834 PF16118.5 CDJ37504.1 - 7.1 7.7 10.0 14 6.7 10.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Connexin PF00029.19 CDJ37504.1 - 8.3 6.1 6.3 12 5.5 6.3 1.3 1 0 0 1 1 1 0 Connexin HEAT PF02985.22 CDJ37505.1 - 0.00029 20.8 24.2 0.00091 19.3 0.2 7.1 7 0 0 7 7 7 2 HEAT repeat Sporozoite_P67 PF05642.11 CDJ37505.1 - 0.0021 16.2 0.9 0.0021 16.2 0.9 2.9 3 1 0 3 3 3 1 Sporozoite P67 surface antigen Cnd1 PF12717.7 CDJ37505.1 - 0.0088 16.1 0.1 15 5.6 0.0 3.8 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 SUIM_assoc PF16619.5 CDJ37505.1 - 0.03 14.4 0.0 0.03 14.4 0.0 14.4 9 3 1 10 10 10 0 Unstructured region C-term to UIM in Ataxin3 SyrA PF11089.8 CDJ37505.1 - 0.58 10.3 0.0 0.58 10.3 0.0 3.0 3 0 0 3 3 3 0 Exopolysaccharide production repressor DUF5564 PF17719.1 CDJ37505.1 - 8.3 6.6 9.4 0.31 11.2 1.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5564) Sporozoite_P67 PF05642.11 CDJ37506.1 - 0.00013 20.2 0.0 0.0015 16.7 0.0 2.2 2 1 0 2 2 2 1 Sporozoite P67 surface antigen RskA PF10099.9 CDJ37506.1 - 0.00093 19.5 23.4 0.0047 17.2 19.0 5.2 1 1 2 4 4 2 2 Anti-sigma-K factor rskA Connexin PF00029.19 CDJ37506.1 - 0.0055 16.5 0.7 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 Connexin DUF4834 PF16118.5 CDJ37506.1 - 0.024 15.6 1.2 0.024 15.6 1.2 4.3 5 0 0 5 5 4 0 Domain of unknown function (DUF4834) dsRBD2 PF17842.1 CDJ37506.1 - 0.041 14.1 6.5 1.2 9.4 0.5 3.2 3 0 0 3 3 3 0 Double-stranded RNA binding domain 2 TRAP_alpha PF03896.16 CDJ37506.1 - 0.15 11.3 3.1 1.1 8.3 0.3 2.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit OATP PF03137.20 CDJ37506.1 - 0.51 8.6 2.5 0.73 8.0 0.3 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TMEM208_SND2 PF05620.11 CDJ37506.1 - 0.52 10.1 4.6 2.4 7.9 0.8 3.0 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Plasmodium_Vir PF05795.11 CDJ37506.1 - 1.1 8.6 9.2 2.1 7.7 3.5 2.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SID-1_RNA_chan PF13965.6 CDJ37506.1 - 1.4 7.3 4.3 0.65 8.3 0.4 2.1 1 1 0 2 2 2 0 dsRNA-gated channel SID-1 Peroxin-13_N PF04088.13 CDJ37506.1 - 9.9 6.4 8.5 2 8.6 0.5 3.2 3 0 0 3 3 3 0 Peroxin 13, N-terminal region SUIM_assoc PF16619.5 CDJ37507.1 - 0.022 14.8 0.6 0.022 14.8 0.6 3.4 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ37507.1 - 0.25 10.2 11.0 1.1 8.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Calpain_inhib PF00748.19 CDJ37507.1 - 1.1 9.8 7.6 5.3 7.5 2.8 2.9 2 0 0 2 2 2 0 Calpain inhibitor Spt20 PF12090.8 CDJ37507.1 - 2.9 7.4 19.5 0.6 9.7 1.7 2.2 2 0 0 2 2 2 0 Spt20 family Med3 PF11593.8 CDJ37507.1 - 3.1 6.9 16.2 2 7.5 4.7 2.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Phostensin_N PF13916.6 CDJ37507.1 - 4.2 7.8 15.2 0.26 11.7 0.3 2.9 2 1 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF2681 PF10883.8 CDJ37507.1 - 6 7.3 14.7 7.6 7.0 2.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ANAPC_CDC26 PF10471.9 CDJ37507.1 - 7.3 7.5 20.0 8.8 7.2 3.2 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF2443 PF10398.9 CDJ37508.1 - 0.0039 17.2 0.0 13 5.9 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2443) MetJ PF01340.20 CDJ37508.1 - 6.1 6.9 5.4 21 5.2 0.1 3.2 3 0 0 3 3 3 0 Met Apo-repressor, MetJ Pkinase PF00069.25 CDJ37509.1 - 1.2e-07 31.3 0.0 2.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ37509.1 - 6.8e-05 22.3 0.0 0.0052 16.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_Tyr PF07714.17 CDJ37509.1 - 0.033 13.5 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase MOZART1 PF12554.8 CDJ37510.1 - 1.5e-20 72.7 0.6 2.3e-20 72.1 0.6 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated p450 PF00067.22 CDJ37510.1 - 0.018 13.8 0.2 0.018 13.8 0.2 1.0 1 0 0 1 1 1 0 Cytochrome P450 Gasdermin_C PF17708.1 CDJ37510.1 - 0.054 13.6 0.2 0.059 13.5 0.2 1.1 1 0 0 1 1 1 0 Gasdermin PUB domain Tubulin PF00091.25 CDJ37511.1 - 3.2e-68 229.8 0.0 6.1e-68 228.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ37511.1 - 3e-42 143.8 0.0 4.5e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDJ37511.1 - 0.00028 21.2 0.0 0.00073 19.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CDJ37511.1 - 0.0053 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 CDJ37511.1 - 0.0065 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF202 PF02656.15 CDJ37512.1 - 0.00016 22.0 0.1 0.065 13.7 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF202) DUF3325 PF11804.8 CDJ37512.1 - 0.066 13.4 0.1 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Dmrt1 PF12374.8 CDJ37513.1 - 0.13 12.7 5.8 2.5 8.6 0.0 3.4 3 0 0 3 3 3 0 Double-sex mab3 related transcription factor 1 Hydrolase PF00702.26 CDJ37514.1 - 0.0058 16.9 0.0 0.052 13.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 CDJ37514.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase Mcl1_mid PF12341.8 CDJ37515.1 - 5.2e-10 39.2 0.0 9.7e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region TT_ORF2 PF02957.15 CDJ37515.1 - 0.66 10.9 4.6 2 9.4 3.9 2.2 1 1 0 1 1 1 0 TT viral ORF2 LRR_8 PF13855.6 CDJ37516.1 - 4.8e-10 39.0 1.9 2.8e-05 23.8 0.0 3.1 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CDJ37516.1 - 9.7e-08 32.2 3.2 0.032 14.7 0.0 4.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ37516.1 - 9.2e-05 22.2 1.7 8.3 6.8 0.0 6.3 7 0 0 7 7 7 1 Leucine Rich repeat adh_short PF00106.25 CDJ37517.1 - 2.9e-28 98.6 3.4 5.3e-26 91.3 3.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ37517.1 - 1.2e-10 41.3 2.7 4.9e-09 36.1 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ37517.1 - 6e-06 26.3 2.6 0.00015 21.8 2.6 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ37517.1 - 0.013 14.9 0.1 2 7.8 0.1 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 CDJ37517.1 - 0.023 14.6 0.4 0.045 13.6 0.2 1.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus Polysacc_synt_2 PF02719.15 CDJ37517.1 - 0.05 12.7 0.1 0.068 12.3 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 CDJ37517.1 - 0.053 12.8 0.4 0.11 11.8 0.4 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 CDJ37517.1 - 0.13 11.6 0.4 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) YqgC PF17430.2 CDJ37519.1 - 4.3 7.5 8.0 15 5.7 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized YqgC-like Adeno_PV PF03910.13 CDJ37519.1 - 7 5.2 13.6 3 6.4 0.9 3.0 2 1 0 2 2 2 0 Adenovirus minor core protein PV Thioredoxin_7 PF13899.6 CDJ37520.1 - 1.1e-11 44.7 0.4 2.1e-11 43.8 0.4 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 CDJ37520.1 - 3.6e-07 29.9 0.0 6.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain DnaT PF17948.1 CDJ37520.1 - 0.49 10.1 2.7 1.1 9.0 0.1 2.9 3 0 0 3 3 3 0 DnaT DNA-binding domain RAP1 PF07218.11 CDJ37520.1 - 4.8 5.3 6.3 6.6 4.9 6.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ABC_membrane PF00664.23 CDJ37521.1 - 3.9e-93 312.0 20.3 1e-46 159.8 1.6 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ37521.1 - 6.8e-65 217.7 0.0 4.3e-33 114.7 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDJ37521.1 - 3.1e-14 52.9 4.7 1.1e-06 28.3 0.6 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CDJ37521.1 - 7.5e-08 32.7 0.3 0.023 15.0 0.0 3.9 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CDJ37521.1 - 2.1e-07 31.0 0.0 0.013 15.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 CDJ37521.1 - 3e-07 29.6 1.1 0.035 12.9 0.1 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 CDJ37521.1 - 4.9e-07 29.4 0.0 0.024 14.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 CDJ37521.1 - 5.7e-07 29.4 0.5 0.0035 17.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CDJ37521.1 - 6.8e-07 29.8 5.6 0.021 15.2 0.2 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CDJ37521.1 - 2.4e-06 27.6 0.0 0.25 11.1 0.0 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDJ37521.1 - 3.7e-06 26.9 0.0 0.013 15.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 CDJ37521.1 - 1e-05 25.2 0.1 0.67 9.5 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 CDJ37521.1 - 2.2e-05 24.9 0.0 0.13 12.7 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDJ37521.1 - 2.8e-05 23.7 0.0 0.048 13.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 CDJ37521.1 - 2.9e-05 24.1 0.0 0.14 12.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Rad17 PF03215.15 CDJ37521.1 - 7.8e-05 22.7 0.2 0.28 11.1 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_28 PF13521.6 CDJ37521.1 - 8.5e-05 22.9 0.3 0.23 11.7 0.1 2.7 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 CDJ37521.1 - 0.00017 21.3 0.2 0.66 9.6 0.0 2.9 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 CDJ37521.1 - 0.00049 19.9 2.2 4.6 6.9 0.0 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein G-alpha PF00503.20 CDJ37521.1 - 0.00049 19.4 0.0 0.73 8.9 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit NB-ARC PF00931.22 CDJ37521.1 - 0.00059 19.1 0.1 0.79 8.9 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain AAA_18 PF13238.6 CDJ37521.1 - 0.00068 20.2 0.9 4.1 8.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 CDJ37521.1 - 0.00098 19.3 3.7 1.6 9.1 0.3 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 CDJ37521.1 - 0.00099 18.4 0.0 0.97 8.7 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 CDJ37521.1 - 0.001 19.6 0.1 2.1 8.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 CDJ37521.1 - 0.002 18.1 1.8 6.8 6.6 0.1 4.2 3 1 1 4 4 4 0 NTPase MMR_HSR1 PF01926.23 CDJ37521.1 - 0.0052 16.9 0.1 4.3 7.5 0.0 3.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase PRK PF00485.18 CDJ37521.1 - 0.007 16.1 0.2 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 CDJ37521.1 - 0.01 16.2 0.1 7.2 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ATPase PF06745.13 CDJ37521.1 - 0.01 15.2 1.1 9.6 5.5 0.0 3.5 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.6 CDJ37521.1 - 0.011 15.5 0.0 0.72 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CDJ37521.1 - 0.022 14.8 0.9 8.6 6.4 0.0 3.4 4 0 0 4 4 3 0 AAA domain TniB PF05621.11 CDJ37521.1 - 0.033 13.6 0.4 19 4.6 0.0 3.7 4 0 0 4 4 4 0 Bacterial TniB protein NACHT PF05729.12 CDJ37521.1 - 0.039 13.9 4.1 8.1 6.3 0.0 3.6 4 0 0 4 4 4 0 NACHT domain AAA_33 PF13671.6 CDJ37521.1 - 0.048 13.8 0.2 8.7 6.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CDJ37521.1 - 0.055 13.2 0.2 15 5.3 0.0 2.8 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 CDJ37521.1 - 0.075 12.2 0.0 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 CDJ37521.1 - 0.076 13.3 0.5 7.8 6.8 0.1 3.2 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 CDJ37521.1 - 0.12 12.2 0.4 22 4.8 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 CDJ37521.1 - 0.13 12.7 6.5 7 7.1 0.3 3.9 4 0 0 4 4 4 0 AAA domain Thioredoxin PF00085.20 CDJ37522.1 - 7.7e-18 64.4 0.1 6.7e-06 26.0 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 CDJ37522.1 - 1.2e-10 41.6 4.2 0.0004 20.3 1.8 3.4 2 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDJ37522.1 - 4e-06 27.1 1.2 0.56 10.6 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CDJ37522.1 - 7.7e-05 23.1 0.1 0.42 11.1 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CDJ37522.1 - 0.0013 18.1 3.9 0.44 9.9 0.7 3.0 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family TrbC_Ftype PF09673.10 CDJ37522.1 - 0.38 10.8 2.7 9.3 6.3 0.1 3.4 2 2 2 4 4 4 0 Type-F conjugative transfer system pilin assembly protein Peptidase_C12 PF01088.21 CDJ37523.1 - 4.8e-21 75.5 0.1 2.2e-18 66.8 0.0 2.9 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CDJ37523.1 - 4.2e-14 52.2 0.3 4.2e-14 52.2 0.3 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases GTP-bdg_M PF16360.5 CDJ37523.1 - 0.01 16.4 0.4 0.14 12.8 0.0 2.3 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region GvpL_GvpF PF06386.11 CDJ37523.1 - 0.018 15.0 6.9 0.027 14.4 6.9 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF MAP65_ASE1 PF03999.12 CDJ37523.1 - 0.022 13.5 0.5 0.031 13.0 0.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) PEP-utilisers_N PF05524.13 CDJ37523.1 - 0.28 11.4 15.1 0.14 12.3 12.3 1.8 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal HTH_Tnp_1 PF01527.20 CDJ37523.1 - 0.43 10.9 0.1 0.43 10.9 0.1 3.0 2 1 1 3 3 3 0 Transposase Pkinase PF00069.25 CDJ37524.1 - 3.8e-05 23.2 2.4 7.4e-05 22.2 0.1 2.3 2 1 0 3 3 3 1 Protein kinase domain SUIM_assoc PF16619.5 CDJ37524.1 - 0.0019 18.2 4.0 0.0019 18.2 4.0 4.0 3 1 1 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 CDJ37524.1 - 0.035 15.1 14.6 1.8 9.5 1.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Pkinase_Tyr PF07714.17 CDJ37524.1 - 0.079 12.2 0.1 0.079 12.2 0.1 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Ribosomal_60s PF00428.19 CDJ37524.1 - 0.1 13.2 22.0 12 6.5 0.0 3.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein PGM_PMM_I PF02878.16 CDJ37525.1 - 9.6e-34 116.1 0.1 3.8e-33 114.1 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CDJ37525.1 - 0.00024 21.7 0.0 0.00097 19.7 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ACP_syn_III_C PF08541.10 CDJ37526.1 - 1.5e-36 124.4 0.7 3.2e-36 123.4 0.1 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 CDJ37526.1 - 5.9e-24 83.7 2.9 7.9e-24 83.3 0.5 2.7 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_C PF02797.15 CDJ37526.1 - 2.3e-05 24.4 0.0 3.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain AlaDh_PNT_C PF01262.21 CDJ37528.1 - 8.2e-72 241.0 0.1 1.2e-71 240.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 CDJ37528.1 - 1e-41 142.4 0.2 1.8e-41 141.7 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Pyr_redox PF00070.27 CDJ37528.1 - 0.00066 20.2 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 CDJ37528.1 - 0.0008 18.8 0.0 0.0024 17.3 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 CDJ37528.1 - 0.0036 16.6 0.3 0.0077 15.5 0.2 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CDJ37528.1 - 0.029 14.8 0.1 0.069 13.6 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding zf-RanBP PF00641.18 CDJ37528.1 - 0.046 13.0 1.6 0.064 12.6 0.2 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others 3HCDH_N PF02737.18 CDJ37528.1 - 0.059 13.3 0.5 0.23 11.3 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CDJ37528.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 CDJ37528.1 - 0.066 12.3 0.2 0.092 11.8 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 CDJ37528.1 - 0.24 11.0 0.6 0.41 10.2 0.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.7 CDJ37528.1 - 0.82 9.0 3.6 1.2 8.3 3.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ37528.1 - 4.9 7.4 8.4 18 5.7 1.8 3.6 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.16 CDJ37529.1 - 6.6e-36 124.0 30.2 1.7e-30 106.1 21.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ37529.1 - 1.3e-08 34.1 1.7 1.3e-08 34.1 1.7 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 CDJ37529.1 - 0.042 12.7 7.6 0.35 9.7 8.8 2.0 1 1 0 1 1 1 0 MFS_1 like family DUF2514 PF10721.9 CDJ37529.1 - 3.2 7.7 6.0 2 8.4 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) SET PF00856.28 CDJ37531.1 - 3.4e-12 47.1 0.0 6.1e-11 43.0 0.0 2.7 2 1 0 2 2 2 1 SET domain DUF4175 PF13779.6 CDJ37531.1 - 1.2 7.0 18.1 1.6 6.5 18.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DDRGK PF09756.9 CDJ37531.1 - 6.6 6.3 13.9 10 5.6 13.9 1.2 1 0 0 1 1 1 0 DDRGK domain RPN7 PF10602.9 CDJ37532.1 - 9.2e-07 28.7 1.5 0.02 14.6 0.1 4.1 3 1 0 3 3 3 2 26S proteasome subunit RPN7 Mad3_BUB1_I PF08311.12 CDJ37532.1 - 4.9e-06 26.5 14.0 0.56 10.2 0.0 7.5 6 2 2 8 8 8 2 Mad3/BUB1 homology region 1 Suf PF05843.14 CDJ37532.1 - 2.2e-05 24.6 13.2 11 5.8 0.0 5.4 4 1 0 4 4 4 3 Suppressor of forked protein (Suf) TPR_8 PF13181.6 CDJ37532.1 - 0.00059 19.9 13.6 0.66 10.3 0.1 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat PPR PF01535.20 CDJ37532.1 - 0.0016 18.6 0.5 2.9 8.3 0.0 4.7 4 0 0 4 4 4 1 PPR repeat TPR_12 PF13424.6 CDJ37532.1 - 0.042 14.1 28.5 0.12 12.7 0.9 7.2 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ37532.1 - 0.086 12.9 17.0 3 8.1 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ37532.1 - 0.12 13.3 0.2 0.12 13.3 0.2 13.7 11 6 6 17 17 17 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ37532.1 - 0.13 12.4 35.0 0.65 10.3 0.1 10.1 12 0 0 12 12 12 0 Tetratricopeptide repeat CKAP2_C PF15297.6 CDJ37532.1 - 0.15 11.2 5.1 0.25 10.4 0.0 2.8 3 0 0 3 3 3 0 Cytoskeleton-associated protein 2 C-terminus Ras PF00071.22 CDJ37533.1 - 5.9e-50 169.0 0.0 7.2e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ37533.1 - 4e-31 107.7 0.0 8.2e-31 106.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ37533.1 - 2.1e-12 46.8 0.0 2.9e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ37533.1 - 0.00033 20.7 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ37533.1 - 0.00043 19.7 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDJ37533.1 - 0.00097 19.1 0.0 0.26 11.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase RNA_helicase PF00910.22 CDJ37533.1 - 0.0011 19.3 0.2 0.013 15.9 0.2 2.3 1 1 0 1 1 1 1 RNA helicase ArgoMid PF16487.5 CDJ37533.1 - 0.0073 16.5 0.1 0.016 15.4 0.1 1.6 1 1 0 1 1 1 1 Mid domain of argonaute GTP_EFTU PF00009.27 CDJ37533.1 - 0.011 15.3 0.7 0.06 12.9 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CDJ37533.1 - 0.016 15.6 0.0 0.029 14.7 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 CDJ37533.1 - 0.042 13.4 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 CDJ37533.1 - 0.052 12.7 0.1 0.11 11.7 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.18 CDJ37533.1 - 0.071 12.4 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.15 CDJ37533.1 - 0.096 12.6 0.7 0.13 12.1 0.1 1.5 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 CDJ37533.1 - 0.14 12.4 0.2 0.53 10.6 0.1 2.0 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CDJ37533.1 - 0.15 12.2 0.3 0.4 10.8 0.1 1.7 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDJ37533.1 - 0.15 12.1 0.6 0.42 10.6 0.1 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) PAN_1 PF00024.26 CDJ37535.1 - 4.5e-63 209.2 84.6 3.9e-08 33.1 1.0 11.2 7 3 4 11 11 11 11 PAN domain PAN_4 PF14295.6 CDJ37535.1 - 1.6e-42 143.2 65.3 1.2e-06 28.3 0.7 11.8 11 0 0 11 11 11 11 PAN domain PAN_2 PF08276.11 CDJ37535.1 - 0.00011 22.2 80.1 0.0021 18.1 1.0 11.4 11 1 1 12 12 12 7 PAN-like domain PAN_3 PF08277.12 CDJ37535.1 - 0.00099 18.9 64.3 0.55 10.1 0.1 11.3 11 0 0 11 11 11 9 PAN-like domain RAP PF08373.10 CDJ37537.1 - 0.097 12.8 0.0 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 RAP domain RskA PF10099.9 CDJ37537.1 - 2.7 8.2 9.5 1.1 9.5 0.7 3.2 1 1 2 3 3 3 0 Anti-sigma-K factor rskA Pkinase PF00069.25 CDJ37539.1 - 1.2e-41 142.8 0.0 1.7e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37539.1 - 1.7e-24 86.5 0.0 2.3e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ37539.1 - 0.00064 19.1 0.2 0.0018 17.7 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CDJ37539.1 - 0.00094 18.9 0.0 0.0038 17.0 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain APH PF01636.23 CDJ37539.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_5 PF13202.6 CDJ37539.1 - 0.0095 15.4 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CDJ37539.1 - 0.018 15.5 0.2 0.048 14.1 0.1 1.8 2 0 0 2 2 2 0 EF-hand domain pair Kdo PF06293.14 CDJ37539.1 - 0.048 13.0 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2_10 PF16588.5 CDJ37539.1 - 0.2 11.4 2.1 0.44 10.3 2.1 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger RCC1 PF00415.18 CDJ37541.1 - 3.6e-20 72.3 12.1 8.4e-08 32.7 0.2 3.8 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ37541.1 - 1.4e-08 34.3 10.6 0.00026 20.7 0.0 4.0 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat SR-25 PF10500.9 CDJ37542.1 - 5.1e-05 23.0 3.5 5.1e-05 23.0 3.5 6.4 5 2 1 6 6 6 3 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ37542.1 - 0.00072 19.9 9.0 0.00072 19.9 9.0 6.6 1 1 2 4 4 4 2 Anti-sigma-K factor rskA eIF-3_zeta PF05091.12 CDJ37542.1 - 0.64 8.9 40.7 2.5 7.0 14.2 3.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) WBS_methylT PF12589.8 CDJ37543.1 - 2.5e-13 50.6 6.9 2.5e-13 50.6 6.9 2.1 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 CDJ37543.1 - 2.1e-08 34.8 0.0 1.6e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ37543.1 - 4.4e-08 33.7 0.0 4.6e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ37543.1 - 0.00031 20.6 0.0 0.0042 16.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ37543.1 - 0.0005 20.8 0.0 0.0026 18.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ37543.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_60s PF00428.19 CDJ37543.1 - 0.019 15.5 2.6 0.05 14.2 2.6 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein TPMT PF05724.11 CDJ37543.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) eIF-3_zeta PF05091.12 CDJ37544.1 - 0.22 10.4 21.2 0.27 10.1 21.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) OSTbeta PF15048.6 CDJ37544.1 - 0.25 11.5 3.2 0.54 10.4 3.2 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein RR_TM4-6 PF06459.12 CDJ37544.1 - 0.4 10.5 14.2 0.69 9.7 14.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ37544.1 - 0.87 8.3 19.3 1.4 7.6 19.3 1.3 1 0 0 1 1 1 0 Presenilin Serinc PF03348.15 CDJ37544.1 - 0.87 8.4 4.5 0.99 8.3 4.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) CLN3 PF02487.17 CDJ37544.1 - 1.2 8.2 11.2 1.7 7.6 11.2 1.2 1 0 0 1 1 1 0 CLN3 protein CPSF100_C PF13299.6 CDJ37544.1 - 2.7 8.1 13.1 13 5.9 11.3 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 CDJ37544.1 - 3.9 6.9 16.4 5.8 6.3 16.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SID-1_RNA_chan PF13965.6 CDJ37544.1 - 4.1 5.7 5.2 5 5.4 5.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 CDJ37544.1 - 4.4 6.4 9.3 7 5.8 9.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 CDJ37544.1 - 5.1 7.1 12.0 7.7 6.5 12.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Velvet PF11754.8 CDJ37544.1 - 6.3 6.7 19.9 1.1 9.2 15.8 1.6 1 1 1 2 2 2 0 Velvet factor Pkinase PF00069.25 CDJ37545.1 - 4.1e-06 26.4 1.9 1.3e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Protein kinase domain Fumble PF03630.14 CDJ37547.1 - 1.6e-74 251.0 0.0 3e-69 233.7 0.0 2.6 2 1 0 2 2 2 2 Fumble Coatomer_WDAD PF04053.14 CDJ37547.1 - 0.082 11.9 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region GET2 PF08690.10 CDJ37547.1 - 0.47 10.1 6.6 0.78 9.4 6.6 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 SLATT_1 PF18181.1 CDJ37548.1 - 0.019 14.9 1.4 0.48 10.4 0.1 2.6 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 DUF872 PF05915.12 CDJ37549.1 - 0.2 11.9 0.2 26 5.0 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF1180 PF06679.12 CDJ37553.1 - 0.67 10.3 6.2 0.76 10.2 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Spt20 PF12090.8 CDJ37553.1 - 1.9 8.0 10.6 2.3 7.8 10.6 1.1 1 0 0 1 1 1 0 Spt20 family DUF4813 PF16072.5 CDJ37553.1 - 2.9 7.5 9.2 3.5 7.2 9.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Macoilin PF09726.9 CDJ37555.1 - 0.08 11.5 26.1 0.086 11.4 10.7 2.3 2 0 0 2 2 2 0 Macoilin family Ndc80_HEC PF03801.13 CDJ37556.1 - 0.17 11.5 6.3 0.22 11.2 6.3 1.2 1 0 0 1 1 1 0 HEC/Ndc80p family Folate_carrier PF01770.18 CDJ37556.1 - 1.1 7.9 2.7 1.1 7.9 2.7 1.0 1 0 0 1 1 1 0 Reduced folate carrier DEAD PF00270.29 CDJ37557.1 - 9.1e-20 71.1 0.9 5.8e-18 65.3 0.9 3.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ37557.1 - 1.3e-13 51.3 0.9 2.1e-12 47.3 0.0 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA PF00004.29 CDJ37557.1 - 0.094 13.1 0.0 12 6.3 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ37557.1 - 5.8 7.2 17.2 88 3.4 5.2 4.7 2 1 0 2 2 2 0 AAA domain Usp PF00582.26 CDJ37558.1 - 4.5e-09 37.0 4.3 4.5e-09 36.9 0.1 2.8 2 2 0 2 2 2 1 Universal stress protein family OMPdecase PF00215.24 CDJ37558.1 - 5.1 6.6 7.8 25 4.4 6.1 2.5 2 1 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family SR-25 PF10500.9 CDJ37559.1 - 0.0022 17.6 4.1 0.0022 17.6 4.1 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ37559.1 - 7.1 6.9 12.4 4.2 7.7 8.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) RTTN_N PF14726.6 CDJ37560.1 - 0.012 16.4 0.7 4.5 8.1 0.2 2.2 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning RTP1_C1 PF10363.9 CDJ37560.1 - 0.024 14.8 0.6 0.34 11.1 0.1 2.3 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 CDJ37560.1 - 0.1 11.1 0.3 0.21 10.1 0.3 1.6 1 1 0 1 1 1 0 Adaptin N terminal region FdhE PF04216.12 CDJ37560.1 - 2 8.2 11.1 1.4 8.7 3.4 2.2 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation RWD PF05773.22 CDJ37561.1 - 3.8e-10 40.1 0.0 1.2e-09 38.5 0.0 1.8 1 1 0 1 1 1 1 RWD domain TAF4 PF05236.14 CDJ37562.1 - 0.0077 16.0 14.6 0.0077 16.0 14.6 3.9 3 1 0 3 3 3 1 Transcription initiation factor TFIID component TAF4 family F-box PF00646.33 CDJ37562.1 - 0.077 12.9 0.3 0.24 11.3 0.3 1.8 1 0 0 1 1 1 0 F-box domain DUF572 PF04502.13 CDJ37562.1 - 2.1 7.9 19.8 0.38 10.3 11.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4667 PF15700.5 CDJ37562.1 - 7.6 6.5 36.4 0.38 10.8 4.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Cob_adeno_trans PF01923.18 CDJ37565.1 - 0.013 15.7 0.5 0.022 14.9 0.5 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase PDEase_I PF00233.19 CDJ37565.1 - 0.031 14.0 1.3 0.031 14.0 1.3 1.9 2 1 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase EzrA PF06160.12 CDJ37565.1 - 0.038 12.2 0.2 0.038 12.2 0.2 1.7 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF2894 PF11445.8 CDJ37565.1 - 0.052 14.0 4.3 0.027 14.9 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) DUF2336 PF10098.9 CDJ37565.1 - 0.061 12.8 4.6 0.046 13.2 2.5 1.9 2 1 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2336) MecA PF05389.12 CDJ37566.1 - 0.67 9.5 7.8 0.51 9.9 4.4 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) FapA PF03961.13 CDJ37566.1 - 4.6 5.7 7.1 8.4 4.9 7.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Metallophos PF00149.28 CDJ37567.1 - 4e-08 34.0 0.0 4.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DNA_pol_E_B PF04042.16 CDJ37567.1 - 0.091 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B RskA PF10099.9 CDJ37568.1 - 0.66 10.2 25.1 2.1 8.6 8.7 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA PFK PF00365.20 CDJ37570.1 - 2.9e-52 177.8 0.1 5.9e-32 111.1 0.0 3.3 3 1 0 3 3 3 3 Phosphofructokinase Hydrolase_3 PF08282.12 CDJ37571.1 - 2.4e-43 148.7 0.0 2.9e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ37571.1 - 1e-07 31.7 0.1 0.00022 20.8 0.1 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CDJ37571.1 - 0.00074 19.9 0.8 0.013 15.8 0.2 2.5 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDJ37571.1 - 0.021 14.9 0.9 0.05 13.7 0.1 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ37571.1 - 0.046 14.1 0.9 0.12 12.8 0.0 2.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase TPR_9 PF13371.6 CDJ37575.1 - 2.1e-09 37.4 1.2 5.3e-08 32.9 0.1 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ37575.1 - 7.1e-06 25.7 0.3 0.37 11.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ37575.1 - 1.2e-05 25.7 0.5 3.2e-05 24.4 0.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ37575.1 - 0.00087 19.0 0.2 0.045 13.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ37575.1 - 0.00089 19.9 1.0 0.011 16.5 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ37575.1 - 0.0057 17.2 0.1 0.34 11.6 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ37575.1 - 0.006 17.2 0.2 0.006 17.2 0.2 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ37575.1 - 0.017 15.3 0.1 0.2 12.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ37575.1 - 0.038 14.2 2.7 0.042 14.1 0.8 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CDJ37575.1 - 0.043 14.2 0.6 0.14 12.6 0.6 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ37575.1 - 0.064 13.3 0.1 14 5.8 0.1 2.6 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 CDJ37575.1 - 0.094 13.0 0.5 0.31 11.4 0.5 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ37575.1 - 0.44 11.3 0.1 0.44 11.3 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_2 PF02230.16 CDJ37576.1 - 6e-48 163.5 0.0 1.1e-47 162.6 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CDJ37576.1 - 9.9e-06 26.3 0.5 2.3e-05 25.1 0.6 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ37576.1 - 0.0016 18.1 0.1 0.022 14.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ37576.1 - 0.0019 17.5 0.8 0.37 10.0 0.2 2.8 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 CDJ37576.1 - 0.0025 17.4 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase FSH1 PF03959.13 CDJ37576.1 - 0.0097 15.6 0.0 0.041 13.5 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 CDJ37576.1 - 0.01 15.7 0.0 0.027 14.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2920 PF11144.8 CDJ37576.1 - 0.055 12.6 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 CDJ37576.1 - 0.11 11.9 0.1 4.6 6.6 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family Esterase PF00756.20 CDJ37576.1 - 0.17 11.5 0.3 0.57 9.8 0.3 2.0 1 1 0 1 1 1 0 Putative esterase p25-alpha PF05517.12 CDJ37577.1 - 0.014 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 p25-alpha CENP-N PF05238.13 CDJ37577.1 - 0.076 12.3 10.2 0.76 9.0 0.9 2.2 2 0 0 2 2 2 0 Kinetochore protein CHL4 like TFIIA PF03153.13 CDJ37577.1 - 2 8.3 20.5 3.5 7.5 3.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Utp14 PF04615.13 CDJ37577.1 - 3.7 6.0 22.8 2 6.9 7.6 2.1 2 0 0 2 2 2 0 Utp14 protein AT_hook PF02178.19 CDJ37578.1 - 2.2 8.4 11.4 0.29 11.1 5.3 3.1 2 0 0 2 2 2 0 AT hook motif RskA PF10099.9 CDJ37579.1 - 1.6e-05 25.2 78.3 0.011 16.1 31.1 4.2 1 1 2 3 3 3 2 Anti-sigma-K factor rskA BAF1_ABF1 PF04684.13 CDJ37579.1 - 0.0043 16.2 14.6 0.0099 15.0 14.6 1.6 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor SID-1_RNA_chan PF13965.6 CDJ37579.1 - 0.64 8.4 4.3 0.92 7.8 4.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Mcm10 PF09332.11 CDJ37579.1 - 0.93 8.9 22.7 1.8 7.9 22.7 1.4 1 0 0 1 1 1 0 Mcm10 replication factor DUF5523 PF17661.1 CDJ37579.1 - 1 9.0 18.1 0.025 14.3 11.4 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5523) DUF4484 PF14831.6 CDJ37579.1 - 2.8 7.9 13.5 0.18 11.8 6.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Paramyxo_ncap PF00973.19 CDJ37579.1 - 3.9 6.3 9.5 6.6 5.5 9.5 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein LMBR1 PF04791.16 CDJ37579.1 - 4.3 6.1 5.8 0.31 9.9 1.2 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein Zip PF02535.22 CDJ37580.1 - 8.1e-31 107.5 9.8 8.1e-31 107.5 9.8 2.8 2 1 1 3 3 3 1 ZIP Zinc transporter FAM176 PF14851.6 CDJ37580.1 - 0.078 12.6 4.1 0.84 9.3 1.3 2.9 2 0 0 2 2 2 0 FAM176 family Tfb4 PF03850.14 CDJ37580.1 - 0.53 9.7 10.6 0.057 12.9 5.8 1.8 2 0 0 2 2 2 0 Transcription factor Tfb4 DUF1216 PF06746.11 CDJ37582.1 - 4.4 7.3 5.4 7.9 6.5 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) B9-C2 PF07162.11 CDJ37583.1 - 7.2e-15 55.6 0.0 1e-14 55.1 0.0 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF4733 PF15878.5 CDJ37583.1 - 0.036 14.5 0.4 0.092 13.2 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4733) Spt20 PF12090.8 CDJ37583.1 - 0.076 12.6 5.6 0.11 12.1 5.6 1.3 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 CDJ37583.1 - 0.72 9.4 9.3 3.4 7.2 5.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ37583.1 - 4.6 7.4 13.3 3.3 7.9 10.0 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PET117 PF15786.5 CDJ37584.1 - 0.1 12.8 0.1 0.1 12.8 0.1 1.9 2 1 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Sina PF03145.16 CDJ37585.1 - 5.9e-24 85.1 8.1 5e-14 52.7 2.5 2.2 2 0 0 2 2 2 2 Seven in absentia protein family SPX PF03105.19 CDJ37585.1 - 0.7 9.7 5.7 1.3 8.9 5.7 1.6 1 1 0 1 1 1 0 SPX domain FtsJ PF01728.19 CDJ37587.1 - 5.2e-56 189.5 1.2 6.2e-56 189.3 1.2 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF2722 PF10846.8 CDJ37587.1 - 7e-05 22.0 18.2 0.016 14.2 12.7 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ37587.1 - 0.0078 16.3 10.6 0.0078 16.3 10.6 4.5 3 1 0 3 3 2 2 Unstructured region C-term to UIM in Ataxin3 OmpH PF03938.14 CDJ37587.1 - 0.01 16.2 22.8 0.13 12.6 5.7 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) IER PF05760.12 CDJ37587.1 - 0.01 16.2 10.5 0.01 16.2 10.5 2.2 1 1 0 2 2 2 0 Immediate early response protein (IER) Spt20 PF12090.8 CDJ37587.1 - 0.02 14.5 15.4 0.02 14.5 15.4 2.8 3 0 0 3 3 3 0 Spt20 family eIF3_p135 PF12807.7 CDJ37587.1 - 0.041 13.9 3.6 0.076 13.0 3.6 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 DUF4834 PF16118.5 CDJ37587.1 - 0.099 13.6 11.7 0.15 13.0 4.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Methyltransf_23 PF13489.6 CDJ37587.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.7 1 1 0 2 2 1 0 Methyltransferase domain BLOC1S3 PF15753.5 CDJ37587.1 - 0.18 12.0 8.8 1.4 9.0 2.5 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Presenilin PF01080.17 CDJ37587.1 - 0.6 8.8 6.9 0.93 8.2 6.9 1.2 1 0 0 1 1 1 0 Presenilin Eaf7 PF07904.13 CDJ37587.1 - 1.8 9.0 6.1 8.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 eIF_4EBP PF05456.11 CDJ37587.1 - 1.9 8.5 6.4 1.6 8.7 2.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) FAM177 PF14774.6 CDJ37587.1 - 2.1 8.7 11.7 1.1 9.7 0.5 2.3 2 0 0 2 2 2 0 FAM177 family IMUP PF15761.5 CDJ37588.1 - 0.021 15.5 1.9 0.021 15.5 1.9 8.9 9 2 0 9 9 9 0 Immortalisation up-regulated protein rRNA_proc-arch PF13234.6 CDJ37589.1 - 5.7e-48 164.2 0.0 1.1e-47 163.2 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 CDJ37589.1 - 1.4e-47 161.4 1.5 6.7e-47 159.2 0.2 2.8 2 1 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 CDJ37589.1 - 7.8e-20 71.4 0.1 9.6e-19 67.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ37589.1 - 3.4e-07 30.6 0.0 5.6e-06 26.7 0.0 2.5 1 1 1 2 2 2 1 Helicase conserved C-terminal domain SR-25 PF10500.9 CDJ37589.1 - 0.26 10.9 33.2 1.2 8.7 1.9 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Lzipper-MIP1 PF14389.6 CDJ37589.1 - 1.1 9.6 6.5 11 6.4 3.1 3.5 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Ras PF00071.22 CDJ37590.1 - 7.5e-66 220.7 0.6 8.8e-66 220.5 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ37590.1 - 4.7e-36 123.6 0.1 8.1e-36 122.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ37590.1 - 1.8e-18 66.6 0.1 2.3e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CDJ37590.1 - 1.9e-05 24.2 0.1 2.5e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDJ37590.1 - 2.7e-05 23.6 0.1 3.6e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDJ37590.1 - 3.9e-05 23.6 0.5 0.13 12.1 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDJ37590.1 - 7.3e-05 22.8 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ37590.1 - 0.00031 20.3 0.4 0.00064 19.3 0.4 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_5 PF07728.14 CDJ37590.1 - 0.015 15.3 0.0 0.041 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 CDJ37590.1 - 0.018 14.8 0.1 0.057 13.2 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CDJ37590.1 - 0.032 14.6 0.0 0.051 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain SMP_C2CD2L PF18696.1 CDJ37590.1 - 0.039 13.8 0.4 0.11 12.3 0.8 1.5 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain FeoB_N PF02421.18 CDJ37590.1 - 0.044 13.3 0.1 0.34 10.4 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 CDJ37590.1 - 0.046 14.0 0.0 0.079 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDJ37590.1 - 0.049 13.4 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Septin PF00735.18 CDJ37590.1 - 0.071 12.4 0.1 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 CDJ37590.1 - 0.08 12.4 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 CDJ37590.1 - 0.094 12.4 0.3 0.71 9.6 0.0 2.3 1 1 2 3 3 3 0 AAA domain AAA PF00004.29 CDJ37590.1 - 0.12 12.8 0.2 2.4 8.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SUIM_assoc PF16619.5 CDJ37591.1 - 0.023 14.8 2.3 0.023 14.8 2.3 3.3 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 CDC27 PF09507.10 CDJ37591.1 - 0.38 10.1 15.0 0.43 9.9 15.0 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAGA-Tad1 PF12767.7 CDJ37591.1 - 1.6 8.4 14.1 1.8 8.2 14.1 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Neur_chan_memb PF02932.16 CDJ37591.1 - 5.9 6.9 9.4 7.1 6.6 9.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ37591.1 - 7.5 6.4 31.6 11 5.9 31.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCHC_2 PF13696.6 CDJ37592.1 - 1.5e-07 31.1 4.1 3.7e-07 29.8 4.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CDJ37592.1 - 0.0081 16.2 5.2 0.022 14.9 5.2 1.8 1 0 0 1 1 1 1 Zinc knuckle SUIM_assoc PF16619.5 CDJ37592.1 - 0.3 11.2 0.0 0.3 11.2 0.0 3.9 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Collagen PF01391.18 CDJ37593.1 - 0.00089 19.0 3.7 0.00089 19.0 3.7 2.4 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Dimerisation2 PF16864.5 CDJ37594.1 - 0.075 13.0 3.1 0.38 10.7 1.3 3.2 2 0 0 2 2 2 0 Dimerisation domain ELMO_CED12 PF04727.13 CDJ37596.1 - 5.4e-27 95.0 0.0 8e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family His_Phos_2 PF00328.22 CDJ37597.1 - 2.8e-08 33.5 18.6 5.1e-06 26.1 0.0 3.9 4 0 0 4 4 4 3 Histidine phosphatase superfamily (branch 2) eIF-3_zeta PF05091.12 CDJ37597.1 - 3.5 6.5 13.9 11 4.8 14.2 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Adaptin_binding PF10199.9 CDJ37599.1 - 5.3 7.7 0.0 5.3 7.7 0.0 13.6 2 2 1 3 3 3 0 Alpha and gamma adaptin binding protein p34 GDP_Man_Dehyd PF16363.5 CDJ37600.1 - 2.8e-128 428.0 0.0 3.3e-128 427.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDJ37600.1 - 1.9e-64 217.4 0.0 2.5e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CDJ37600.1 - 1.2e-08 34.4 0.0 1.7e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CDJ37600.1 - 0.005 16.0 0.0 0.0098 15.1 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CDJ37600.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family DUF3040 PF11239.8 CDJ37601.1 - 0.63 10.4 3.1 6.9 7.0 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) UCH PF00443.29 CDJ37602.1 - 1.4e-39 136.2 0.0 2.9e-39 135.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ37602.1 - 6.2e-14 52.3 0.0 2.4e-05 24.1 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 CDJ37602.1 - 0.0041 16.8 0.0 0.0072 16.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal FliM PF02154.15 CDJ37602.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Pyr_redox_2 PF07992.14 CDJ37603.1 - 2.1e-35 122.4 0.1 8.8e-27 94.1 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ37603.1 - 2.1e-12 47.4 0.0 3.4e-10 40.3 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Band_7 PF01145.25 CDJ37603.1 - 0.023 14.7 0.7 0.049 13.6 0.7 1.6 1 0 0 1 1 1 0 SPFH domain / Band 7 family NAD_binding_8 PF13450.6 CDJ37603.1 - 0.11 12.8 7.8 0.33 11.2 0.0 3.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 CDJ37603.1 - 0.11 12.9 0.1 0.52 10.8 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 CDJ37603.1 - 0.18 10.4 1.1 1.9 7.1 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Corona_nucleoca PF00937.18 CDJ37604.1 - 0.068 12.2 3.8 0.21 10.6 3.8 1.8 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CNDH2_C PF16858.5 CDJ37605.1 - 6.3e-11 42.7 0.4 1.2e-10 41.7 0.4 1.5 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 CDJ37605.1 - 2e-06 28.0 0.9 1.3e-05 25.3 0.0 2.6 2 1 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF1635 PF07795.11 CDJ37605.1 - 0.39 10.5 6.8 0.035 13.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) AF-4 PF05110.13 CDJ37605.1 - 1.4 6.9 8.5 2.1 6.3 8.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Arf PF00025.21 CDJ37606.1 - 2.2e-66 222.6 0.0 2.5e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CDJ37606.1 - 4.9e-12 45.7 0.5 2.6e-07 30.1 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CDJ37606.1 - 7.6e-12 45.5 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ37606.1 - 3.5e-10 39.7 0.0 4.3e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CDJ37606.1 - 3.1e-09 36.5 0.0 4.1e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDJ37606.1 - 1.3e-06 28.5 0.0 1.7e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ37606.1 - 2.7e-05 23.6 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDJ37606.1 - 0.0087 15.6 0.0 0.033 13.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 CDJ37606.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain PPK2 PF03976.14 CDJ37606.1 - 0.2 11.1 0.2 0.36 10.3 0.1 1.5 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) DLIC PF05783.11 CDJ37606.1 - 0.21 10.4 0.0 0.61 8.9 0.0 1.6 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Peptidase_M14 PF00246.24 CDJ37607.1 - 4.7e-09 36.5 0.0 1e-08 35.4 0.0 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase DUF5532 PF17673.1 CDJ37607.1 - 0.095 12.8 0.0 2.9 8.0 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5532) CPBP PF02517.16 CDJ37608.1 - 7.3e-08 32.7 0.3 3.3e-07 30.6 0.4 2.3 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease EcsB PF05975.12 CDJ37608.1 - 0.06 12.2 0.1 0.12 11.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Peptidase_C1 PF00112.23 CDJ37609.1 - 7.5e-06 26.2 0.0 8.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.11 CDJ37611.1 - 3.6e-13 49.8 0.6 5.3e-12 46.1 0.0 2.7 2 1 0 2 2 2 1 Cathepsin C exclusion domain Vma12 PF11712.8 CDJ37613.1 - 6.2e-06 26.3 0.2 8.4e-05 22.7 0.0 2.3 2 1 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase HEPN_STY4199 PF18729.1 CDJ37613.1 - 0.054 12.7 2.9 0.056 12.6 0.6 1.9 2 0 0 2 2 2 0 STY4199-like HEPN TMEM187 PF15100.6 CDJ37613.1 - 0.076 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 TMEM187 protein family Orf78 PF06024.12 CDJ37613.1 - 0.087 13.1 3.7 0.64 10.3 0.0 2.7 2 1 0 2 2 2 0 Orf78 (ac78) IstB_IS21_ATP PF08483.11 CDJ37613.1 - 0.27 11.2 0.1 0.27 11.2 0.1 3.0 3 0 0 3 3 3 0 IstB-like ATP binding N-terminal Neur_chan_memb PF02932.16 CDJ37613.1 - 0.53 10.3 4.6 2.1 8.4 5.0 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Otopetrin PF03189.13 CDJ37613.1 - 0.7 8.6 2.1 1 8.1 0.0 1.9 2 0 0 2 2 2 0 Otopetrin Ndc1_Nup PF09531.10 CDJ37613.1 - 1.7 7.2 13.8 15 4.1 11.5 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 CDJ37613.1 - 2.4 6.6 9.2 2.9 6.3 9.2 1.2 1 0 0 1 1 1 0 Macoilin family Folliculin PF11704.8 CDJ37613.1 - 8.6 6.2 7.5 20 5.0 6.5 2.1 2 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Pribosyltran PF00156.27 CDJ37614.1 - 1.4e-21 76.7 0.0 1.8e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 CDJ37614.1 - 0.092 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Ras PF00071.22 CDJ37615.1 - 7.3e-34 116.7 0.0 1.7e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ37615.1 - 2e-12 47.4 0.0 9.1e-12 45.3 0.0 2.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ37615.1 - 0.0028 17.1 0.0 0.0077 15.7 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF4821 PF16092.5 CDJ37616.1 - 1.6e-32 113.2 2.2 4.5e-30 105.2 0.1 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF4821) YdjM PF04307.14 CDJ37616.1 - 0.001 18.4 5.2 0.001 18.4 5.2 3.0 3 1 0 3 3 3 1 LexA-binding, inner membrane-associated putative hydrolase Transposase_24 PF03004.14 CDJ37616.1 - 0.0018 18.4 0.7 0.0018 18.4 0.7 3.0 2 1 1 3 3 3 1 Plant transposase (Ptta/En/Spm family) RNA_pol_Rpc4 PF05132.14 CDJ37616.1 - 0.098 13.1 5.6 23 5.4 0.0 3.6 3 0 0 3 3 3 0 RNA polymerase III RPC4 Acetyltransf_1 PF00583.25 CDJ37616.1 - 0.14 12.4 0.0 0.38 11.0 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Apt1 PF10351.9 CDJ37616.1 - 1.9 7.2 22.5 2.6 6.8 3.2 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain BAF1_ABF1 PF04684.13 CDJ37616.1 - 3.4 6.6 13.0 2.9 6.8 0.2 2.4 1 1 1 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor SR-25 PF10500.9 CDJ37618.1 - 7.8e-05 22.4 4.7 9.9e-05 22.1 4.7 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ37618.1 - 0.014 16.1 2.5 0.019 15.7 2.5 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF4834 PF16118.5 CDJ37618.1 - 0.16 12.9 0.9 0.23 12.4 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ37618.1 - 0.56 10.2 7.1 0.6 10.0 7.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ37618.1 - 0.71 9.4 14.1 0.78 9.3 14.1 1.2 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ37618.1 - 7.4 5.3 16.2 9.3 5.0 16.2 1.3 1 0 0 1 1 1 0 Androgen receptor DUF3446 PF11928.8 CDJ37618.1 - 8.1 6.8 13.4 14 6.1 13.4 1.4 1 1 0 1 1 1 0 Early growth response N-terminal domain TFIIA PF03153.13 CDJ37618.1 - 9.3 6.1 17.9 10 6.0 17.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3824 PF12868.7 CDJ37619.1 - 0.001 19.7 8.2 0.0015 19.2 8.2 1.2 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) DUF5427 PF10310.9 CDJ37619.1 - 0.0063 15.5 13.3 0.0073 15.3 13.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) SARAF PF06682.12 CDJ37619.1 - 0.029 14.0 11.4 0.037 13.7 11.4 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Velvet PF11754.8 CDJ37619.1 - 0.044 13.7 12.5 0.057 13.3 12.5 1.1 1 0 0 1 1 1 0 Velvet factor HemX PF04375.14 CDJ37619.1 - 0.051 12.8 28.8 0.065 12.5 28.8 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase CDC45 PF02724.14 CDJ37619.1 - 0.077 11.3 6.5 0.079 11.3 6.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Miga PF10265.9 CDJ37619.1 - 0.16 10.9 4.6 0.19 10.7 4.6 1.0 1 0 0 1 1 1 0 Mitoguardin DUF4569 PF15133.6 CDJ37619.1 - 0.24 11.1 12.6 0.32 10.7 12.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) SLC12 PF03522.15 CDJ37619.1 - 0.44 9.5 11.7 0.46 9.5 11.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 TFIIA PF03153.13 CDJ37619.1 - 0.59 10.1 36.7 0.71 9.8 36.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Golgin_A5 PF09787.9 CDJ37619.1 - 0.85 9.0 19.1 1 8.7 19.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1387 PF07139.11 CDJ37619.1 - 0.85 9.3 13.1 1 9.0 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Suf PF05843.14 CDJ37619.1 - 0.9 9.5 18.7 1 9.3 18.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ37619.1 - 0.98 8.1 18.3 1.2 7.9 18.3 1.0 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ37619.1 - 1.6 7.6 16.6 2.3 7.1 16.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zip PF02535.22 CDJ37619.1 - 1.6 7.9 5.4 1.9 7.6 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.9 CDJ37619.1 - 1.7 6.8 26.9 1.9 6.7 26.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ37619.1 - 1.7 8.6 11.3 2 8.4 11.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ37619.1 - 2 8.2 16.6 2.5 7.8 16.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ37619.1 - 2.1 8.3 8.5 2.7 8.0 8.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF2052 PF09747.9 CDJ37619.1 - 2.4 8.3 15.6 3 7.9 15.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3810 PF12725.7 CDJ37619.1 - 2.9 7.1 4.4 4 6.7 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) CLN3 PF02487.17 CDJ37619.1 - 3 6.8 6.1 3.5 6.6 6.1 1.2 1 0 0 1 1 1 0 CLN3 protein Lin-8 PF03353.15 CDJ37619.1 - 3 7.3 17.4 3.6 7.1 17.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist 5_nucleotid PF05761.14 CDJ37619.1 - 3.2 6.5 7.0 3.8 6.3 7.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family OmpH PF03938.14 CDJ37619.1 - 3.6 7.9 35.5 5.6 7.3 35.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3450 PF11932.8 CDJ37619.1 - 4.1 6.6 25.7 5.3 6.3 25.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MAJIN PF15077.6 CDJ37619.1 - 4.1 7.1 11.1 5.2 6.8 11.1 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Hid1 PF12722.7 CDJ37619.1 - 4.3 5.3 13.4 4.8 5.2 13.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WTX PF09422.10 CDJ37619.1 - 5 6.1 13.6 5.9 5.9 13.6 1.0 1 0 0 1 1 1 0 WTX protein V_ATPase_I PF01496.19 CDJ37619.1 - 5 4.9 10.2 6 4.7 10.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GREB1 PF15782.5 CDJ37619.1 - 5.1 4.1 13.4 5.4 4.0 13.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4407 PF14362.6 CDJ37619.1 - 5.2 6.3 15.2 6.1 6.1 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MAT1 PF06391.13 CDJ37619.1 - 6.4 6.5 18.0 8.8 6.1 18.0 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 ALMT PF11744.8 CDJ37619.1 - 7 5.4 9.7 8 5.2 9.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Ndc1_Nup PF09531.10 CDJ37619.1 - 7.7 5.1 15.4 8.4 4.9 15.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Kinesin PF00225.23 CDJ37620.1 - 7.2e-86 288.1 2.0 1.8e-43 148.7 0.0 2.8 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ37620.1 - 1.7e-21 76.7 0.4 1.4e-20 73.8 0.4 2.6 1 1 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 CDJ37620.1 - 1.1e-05 25.7 0.1 7.2e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 Kinesin protein 1B Kinesin_assoc PF16183.5 CDJ37620.1 - 0.00072 19.7 13.4 0.0019 18.4 0.0 4.1 4 0 0 4 4 4 2 Kinesin-associated FHA PF00498.26 CDJ37620.1 - 0.0028 18.0 0.0 0.0077 16.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain Ion_trans PF00520.31 CDJ37621.1 - 3.4e-46 157.5 73.4 4.5e-16 58.8 17.9 4.3 4 0 0 4 4 4 4 Ion transport protein WD40 PF00400.32 CDJ37623.1 - 9.4e-10 38.9 11.1 0.72 10.8 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ37623.1 - 0.00019 21.6 0.0 0.45 10.9 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain IFT57 PF10498.9 CDJ37625.1 - 0.25 10.2 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 IFT57 PF10498.9 CDJ37626.1 - 0.003 16.6 4.4 0.0051 15.8 4.4 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Exonuc_VII_L PF02601.15 CDJ37626.1 - 0.025 14.1 11.0 0.038 13.6 11.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 CDJ37626.1 - 0.067 12.1 12.6 0.11 11.4 12.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Retrotrans_gag PF03732.17 CDJ37626.1 - 0.09 13.1 3.7 0.056 13.7 1.4 1.8 1 1 1 2 2 2 0 Retrotransposon gag protein Caps_synth_GfcC PF06251.11 CDJ37626.1 - 0.095 12.3 2.7 0.16 11.6 2.7 1.3 1 0 0 1 1 1 0 Capsule biosynthesis GfcC BRCA-2_OB3 PF09104.10 CDJ37626.1 - 0.1 12.2 0.7 0.18 11.5 0.7 1.4 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 FapA PF03961.13 CDJ37626.1 - 0.2 10.2 1.5 0.27 9.8 1.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Striatin PF08232.12 CDJ37626.1 - 1.9 9.0 15.2 0.27 11.8 7.4 2.2 2 0 0 2 2 2 0 Striatin family TT_ORF2 PF02957.15 CDJ37626.1 - 1.9 9.4 9.3 2.5 9.0 3.9 2.4 2 0 0 2 2 2 0 TT viral ORF2 RNA_pol_Rpc4 PF05132.14 CDJ37626.1 - 3 8.2 11.7 4.3 7.7 1.9 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 MCU PF04678.13 CDJ37626.1 - 4.5 7.3 7.3 11 6.0 7.1 1.8 1 1 0 1 1 1 0 Mitochondrial calcium uniporter FYDLN_acid PF09538.10 CDJ37626.1 - 7.4 7.3 9.2 2.5 8.8 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Halogen_Hydrol PF10112.9 CDJ37627.1 - 5.1 7.1 11.3 0.11 12.4 1.2 3.0 2 2 1 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Spc42p PF11544.8 CDJ37628.1 - 0.00011 22.2 2.7 0.00011 22.2 2.7 9.3 7 3 1 9 9 9 2 Spindle pole body component Spc42p SUIM_assoc PF16619.5 CDJ37629.1 - 1.2 9.3 6.0 2.8 8.1 6.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 AAA_11 PF13086.6 CDJ37630.1 - 6.1e-24 85.2 0.4 7e-24 85.0 0.4 1.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ37630.1 - 0.012 15.3 0.1 0.013 15.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 CDJ37630.1 - 0.034 13.9 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CDJ37630.1 - 0.093 13.1 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 CDJ37630.1 - 0.16 11.1 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase Thioredoxin PF00085.20 CDJ37632.1 - 9.2e-12 44.9 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CDJ37632.1 - 0.00064 19.9 0.1 0.0023 18.1 0.1 2.0 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CDJ37632.1 - 0.002 18.5 0.0 0.09 13.2 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.24 CDJ37632.1 - 0.03 14.5 0.0 0.077 13.2 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_8 PF13905.6 CDJ37632.1 - 0.12 12.8 0.0 0.28 11.5 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like SAP130_C PF16014.5 CDJ37632.1 - 0.16 11.0 11.0 0.21 10.6 11.0 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Ank_5 PF13857.6 CDJ37633.1 - 0.0066 16.7 0.0 0.88 10.0 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Pkinase PF00069.25 CDJ37634.1 - 2.8e-41 141.7 0.0 7.5e-41 140.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37634.1 - 3.2e-22 79.1 0.0 1.9e-20 73.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CDJ37634.1 - 0.00036 19.9 0.0 0.004 16.5 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ37634.1 - 0.015 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 CDJ37634.1 - 0.19 11.3 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Ribosomal_S21e PF01249.18 CDJ37636.1 - 3.4e-37 126.4 0.0 3.8e-37 126.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e CCDC53 PF10152.9 CDJ37637.1 - 0.0074 16.7 6.4 0.17 12.3 6.4 2.3 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex TFIIA PF03153.13 CDJ37637.1 - 0.049 13.6 11.4 0.073 13.1 11.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ37637.1 - 0.089 12.9 24.3 0.44 10.6 0.6 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Het-C PF07217.11 CDJ37637.1 - 0.13 10.8 2.0 0.22 10.0 2.0 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C FKBP_N PF01346.18 CDJ37637.1 - 0.86 10.6 7.5 3.2 8.8 7.5 2.0 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF4175 PF13779.6 CDJ37637.1 - 1.1 7.1 16.2 1.7 6.5 16.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ribosomal_60s PF00428.19 CDJ37637.1 - 5.5 7.6 9.8 0.38 11.4 0.6 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein CD20 PF04103.15 CDJ37638.1 - 0.023 14.8 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 CD20-like family Velvet PF11754.8 CDJ37638.1 - 0.35 10.8 0.0 0.35 10.8 0.0 3.1 2 2 0 2 2 2 0 Velvet factor CytB6-F_Fe-S PF08802.10 CDJ37640.1 - 0.17 11.9 0.1 0.17 11.9 0.1 4.3 3 1 1 4 4 4 0 Cytochrome B6-F complex Fe-S subunit Lin-8 PF03353.15 CDJ37640.1 - 2.3 7.7 7.8 3.7 7.0 7.8 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Stevor PF17410.2 CDJ37640.1 - 2.8 7.4 4.9 1 8.9 2.1 1.7 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame Hid1 PF12722.7 CDJ37640.1 - 4.5 5.3 6.6 7.6 4.5 6.6 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF898 PF05987.13 CDJ37640.1 - 4.8 6.1 8.5 40 3.1 6.9 2.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF898) DUF2339 PF10101.9 CDJ37640.1 - 6.1 5.3 27.8 8.8 4.8 27.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) PP-binding PF00550.25 CDJ37641.1 - 1.2e-13 51.2 0.1 1.6e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CDJ37641.1 - 5.5e-06 26.5 0.7 7.8e-06 26.0 0.7 1.3 1 1 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.9 CDJ37641.1 - 0.003 17.7 0.2 0.0045 17.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S Ribosomal_L12_N PF16320.5 CDJ37641.1 - 0.028 14.1 0.1 0.028 14.1 0.1 3.5 4 0 0 4 4 4 0 Ribosomal protein L7/L12 dimerisation domain Flt3_lig PF02947.14 CDJ37641.1 - 0.066 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 flt3 ligand DUF2517 PF10725.9 CDJ37641.1 - 0.1 12.4 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) Sporozoite_P67 PF05642.11 CDJ37642.1 - 3.3e-07 28.8 6.5 3.3e-07 28.8 6.5 2.1 2 1 1 3 3 2 2 Sporozoite P67 surface antigen RAP PF08373.10 CDJ37642.1 - 1.6e-05 24.9 0.0 0.00033 20.7 0.0 2.4 1 1 0 1 1 1 1 RAP domain DUF1645 PF07816.11 CDJ37642.1 - 8.6e-05 23.2 6.1 8.6e-05 23.2 6.1 4.6 3 1 0 3 3 2 1 Protein of unknown function (DUF1645) GNAT_acetyltr_2 PF13718.6 CDJ37642.1 - 0.033 13.6 14.8 0.013 14.9 4.1 2.6 3 0 0 3 3 3 0 GNAT acetyltransferase 2 CNDH2_C PF16858.5 CDJ37642.1 - 0.19 11.6 24.6 0.48 10.2 5.3 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Exonuc_VII_L PF02601.15 CDJ37642.1 - 0.74 9.3 30.9 0.17 11.5 15.6 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit PAT1 PF09770.9 CDJ37642.1 - 1.3 7.2 46.5 1.9 6.7 14.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CLN3 PF02487.17 CDJ37642.1 - 1.4 7.9 16.4 0.88 8.5 4.7 2.4 2 0 0 2 2 2 0 CLN3 protein SPX PF03105.19 CDJ37642.1 - 1.5 8.7 48.5 0.032 14.2 6.6 3.0 3 0 0 3 3 2 0 SPX domain AAA_23 PF13476.6 CDJ37642.1 - 1.5 9.3 38.5 0.63 10.5 19.6 2.5 2 0 0 2 2 2 0 AAA domain MecA PF05389.12 CDJ37642.1 - 1.5 8.4 14.4 2.5 7.7 1.5 2.6 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Connexin PF00029.19 CDJ37642.1 - 3.7 7.2 15.5 7.3 6.3 5.5 2.5 2 0 0 2 2 2 0 Connexin Tyrosinase PF00264.20 CDJ37642.1 - 3.9 7.7 14.7 0.54 10.5 3.8 2.3 2 0 0 2 2 2 0 Common central domain of tyrosinase Macoilin PF09726.9 CDJ37642.1 - 4.8 5.6 53.0 0.023 13.3 8.5 2.5 2 1 0 2 2 2 0 Macoilin family ARA70 PF12489.8 CDJ37643.1 - 0.17 12.1 16.4 0.21 11.8 16.4 1.2 1 0 0 1 1 1 0 Nuclear coactivator Lipocalin_8 PF16585.5 CDJ37643.1 - 0.52 10.7 6.8 0.64 10.5 6.8 1.2 1 0 0 1 1 1 0 Lipocalin-like domain MAT1 PF06391.13 CDJ37643.1 - 3.9 7.2 22.1 4.5 7.0 22.1 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DNA_pol_A PF00476.20 CDJ37644.1 - 1.5e-76 257.9 0.0 2.5e-51 174.9 0.0 2.5 2 1 0 2 2 2 2 DNA polymerase family A 5_3_exonuc PF01367.20 CDJ37644.1 - 1.9e-11 44.4 0.0 5.6e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold SKIP_SNW PF02731.15 CDJ37646.1 - 1.3e-68 229.7 1.3 1.3e-68 229.7 1.3 2.7 3 0 0 3 3 3 1 SKIP/SNW domain SET PF00856.28 CDJ37647.1 - 4.7e-05 23.8 0.0 0.00048 20.5 0.0 2.3 1 1 0 1 1 1 1 SET domain tRNA-synt_1g PF09334.11 CDJ37649.1 - 1.4e-13 50.4 0.1 6.3e-11 41.6 0.0 3.3 3 0 0 3 3 3 2 tRNA synthetases class I (M) RIBIOP_C PF04950.12 CDJ37649.1 - 5.7 6.3 10.1 3.1 7.1 0.1 2.3 2 0 0 2 2 2 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal ABC_tran_CTD PF16326.5 CDJ37651.1 - 0.58 10.4 8.1 0.7 10.2 4.4 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain LcrG PF07216.12 CDJ37651.1 - 5 7.1 9.9 3.4 7.7 5.8 2.5 2 0 0 2 2 2 0 LcrG protein Sporozoite_P67 PF05642.11 CDJ37652.1 - 0.23 9.5 3.0 0.28 9.2 3.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIA PF03153.13 CDJ37652.1 - 0.77 9.7 17.7 4.8 7.1 0.1 2.0 1 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PDEase_I PF00233.19 CDJ37653.1 - 1.6e-45 155.7 5.3 1.6e-45 155.7 5.3 4.4 4 1 0 4 4 4 1 3'5'-cyclic nucleotide phosphodiesterase UPF0242 PF06785.11 CDJ37653.1 - 0.0023 18.0 6.8 0.0023 18.0 6.8 3.5 3 1 0 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus AAA_23 PF13476.6 CDJ37653.1 - 0.0026 18.3 8.6 0.0026 18.3 8.6 3.5 3 0 0 3 3 3 1 AAA domain HD PF01966.22 CDJ37653.1 - 0.077 13.2 0.4 0.18 12.0 0.4 1.7 1 0 0 1 1 1 0 HD domain ABC2_membrane_3 PF12698.7 CDJ37653.1 - 3.9 6.5 11.0 6 5.9 0.6 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein MitMem_reg PF13012.6 CDJ37654.1 - 1.5e-06 28.5 1.1 2.4e-06 27.9 1.1 1.4 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function Gly_acyl_tr_N PF06021.11 CDJ37654.1 - 0.011 15.8 0.4 0.015 15.4 0.4 1.2 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase DUF5624 PF18538.1 CDJ37654.1 - 0.077 13.1 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Spt20 PF12090.8 CDJ37655.1 - 0.0068 16.0 30.3 0.0068 16.0 30.3 3.3 2 1 0 2 2 2 1 Spt20 family Macoilin PF09726.9 CDJ37655.1 - 0.75 8.3 56.9 0.053 12.1 51.7 1.5 1 1 1 2 2 2 0 Macoilin family DUF4638 PF15472.6 CDJ37655.1 - 3.4 7.3 25.8 0.73 9.5 11.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) DUF4647 PF15504.6 CDJ37655.1 - 5.6 5.9 34.1 0.65 9.0 7.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) Ribosomal_S13 PF00416.22 CDJ37656.1 - 1.6e-51 174.0 1.2 1.9e-51 173.8 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CDJ37656.1 - 0.0095 14.7 0.0 0.0095 14.7 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) ISP1_C PF18161.1 CDJ37658.1 - 2.3e-42 143.3 0.5 3.3e-42 142.8 0.5 1.2 1 0 0 1 1 1 1 ISP1 C-terminal ISP3_C PF18045.1 CDJ37658.1 - 3.2e-42 142.8 0.6 4.5e-42 142.4 0.6 1.2 1 0 0 1 1 1 1 ISP3 C-terminal Tim54 PF11711.8 CDJ37658.1 - 0.00041 19.3 5.0 0.00046 19.1 5.0 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Methyltrn_RNA_2 PF04013.12 CDJ37658.1 - 0.0082 15.9 0.4 0.017 14.8 0.3 1.5 1 1 0 1 1 1 1 Putative SAM-dependent RNA methyltransferase CDC45 PF02724.14 CDJ37658.1 - 0.023 13.0 5.7 0.024 12.9 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 CDJ37658.1 - 0.076 13.2 9.1 0.14 12.4 9.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NARP1 PF12569.8 CDJ37658.1 - 0.085 11.7 11.3 0.1 11.5 11.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Zip PF02535.22 CDJ37658.1 - 0.099 11.8 3.1 0.098 11.9 3.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CDJ37658.1 - 0.11 11.2 7.1 0.13 11.0 7.1 1.1 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 CDJ37658.1 - 0.22 10.9 7.0 0.29 10.6 7.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RNA_pol_Rpc4 PF05132.14 CDJ37658.1 - 0.5 10.8 11.3 0.87 10.0 11.3 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Rrn6 PF10214.9 CDJ37658.1 - 0.55 8.7 7.3 0.68 8.3 7.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Connexin PF00029.19 CDJ37658.1 - 0.65 9.7 5.2 0.93 9.2 5.2 1.2 1 0 0 1 1 1 0 Connexin Ndc1_Nup PF09531.10 CDJ37658.1 - 0.73 8.5 4.4 0.73 8.4 4.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2052 PF09747.9 CDJ37658.1 - 0.79 9.8 13.2 1.4 9.0 13.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF913 PF06025.12 CDJ37658.1 - 1.8 7.5 6.5 2.7 6.9 6.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3464 PF11947.8 CDJ37658.1 - 3.2 7.5 9.0 5.8 6.7 9.0 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 FancD2 PF14631.6 CDJ37658.1 - 4.2 4.7 11.3 5.3 4.3 11.3 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RNA_polI_A34 PF08208.11 CDJ37658.1 - 4.5 7.3 22.0 8.6 6.4 22.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 CDJ37658.1 - 5.9 6.6 15.9 9.4 6.0 15.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 CDJ37658.1 - 8.6 5.8 9.1 15 5.0 9.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 JUPITER PF17054.5 CDJ37659.1 - 0.029 13.9 0.1 0.33 10.4 0.1 2.0 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter DUF4057 PF13266.6 CDJ37659.1 - 0.064 13.0 0.2 1.4 8.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4057) SUIM_assoc PF16619.5 CDJ37659.1 - 6.4 6.9 12.0 6 7.0 11.5 1.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SPX PF03105.19 CDJ37660.1 - 0.0002 21.4 12.7 0.038 13.9 0.2 2.2 2 0 0 2 2 2 2 SPX domain DUF4667 PF15700.5 CDJ37660.1 - 0.0024 18.0 29.5 0.078 13.1 9.9 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4667) Apt1 PF10351.9 CDJ37660.1 - 0.013 14.4 19.4 0.043 12.7 0.0 2.4 2 1 0 2 2 2 0 Golgi-body localisation protein domain Sof1 PF04158.14 CDJ37660.1 - 0.065 13.5 6.5 0.14 12.4 6.5 1.5 1 0 0 1 1 1 0 Sof1-like domain RskA PF10099.9 CDJ37660.1 - 0.3 11.4 7.1 3.2 8.0 4.9 2.4 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Nup54 PF13874.6 CDJ37660.1 - 1.5 8.9 5.1 6 7.0 0.8 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DDHD PF02862.17 CDJ37660.1 - 1.8 8.6 11.3 11 6.1 0.1 2.3 3 0 0 3 3 3 0 DDHD domain PepX_C PF08530.10 CDJ37661.1 - 4.1e-10 40.0 0.0 8.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 CDJ37661.1 - 1.9e-05 24.4 0.3 7.5e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Lyase_1 PF00206.20 CDJ37661.1 - 0.13 11.7 1.1 0.25 10.7 1.1 1.4 1 0 0 1 1 1 0 Lyase Ribosomal_S4e PF00900.20 CDJ37662.1 - 2.7e-31 107.3 0.2 1.5e-30 104.9 0.0 2.3 3 0 0 3 3 3 1 Ribosomal family S4e 40S_S4_C PF16121.5 CDJ37662.1 - 3.9e-25 87.2 0.4 8.2e-25 86.2 0.2 1.7 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CDJ37662.1 - 2.3e-19 69.2 9.9 7.4e-19 67.6 9.1 2.1 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 CDJ37662.1 - 4.8e-06 26.2 0.2 1.5e-05 24.6 0.0 2.0 3 0 0 3 3 3 1 S4 domain KOW PF00467.29 CDJ37662.1 - 2.5e-05 24.0 4.0 3.4e-05 23.6 2.2 2.1 2 0 0 2 2 2 1 KOW motif Thioesterase PF00975.20 CDJ37663.1 - 7e-22 78.7 0.4 1.4e-09 38.4 0.0 2.5 1 1 1 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.7 CDJ37663.1 - 3.1e-15 57.4 15.3 8.3e-09 36.4 2.7 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family LIDHydrolase PF10230.9 CDJ37663.1 - 0.0036 16.9 0.0 2.7 7.5 0.0 2.1 2 0 0 2 2 2 2 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 CDJ37663.1 - 0.0071 15.6 0.2 2.8 7.1 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ37663.1 - 0.011 15.4 2.4 2.2 7.9 0.1 2.7 2 1 1 3 3 3 0 alpha/beta hydrolase fold DUF726 PF05277.12 CDJ37663.1 - 0.034 13.1 0.3 2.3 7.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF726) DUF900 PF05990.12 CDJ37663.1 - 0.038 13.5 0.0 8.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 CDJ37663.1 - 0.04 13.1 0.0 8.5 5.4 0.0 2.3 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Cutinase PF01083.22 CDJ37663.1 - 0.048 13.6 0.0 9.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Cutinase DUF452 PF04301.13 CDJ37663.1 - 0.11 12.0 0.0 21 4.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF452) WD40 PF00400.32 CDJ37665.1 - 1.1e-06 29.2 0.6 3.6e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Spt20 PF12090.8 CDJ37665.1 - 0.29 10.7 22.1 0.21 11.2 5.8 2.3 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 CDJ37665.1 - 0.38 10.7 26.4 0.26 11.2 12.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ37665.1 - 5.8 7.1 26.8 0.13 12.3 2.2 2.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PrpF PF04303.13 CDJ37666.1 - 0.35 9.8 2.0 3.1 6.6 0.0 2.1 2 0 0 2 2 2 0 PrpF protein Spt20 PF12090.8 CDJ37667.1 - 0.54 9.8 11.9 0.49 10.0 11.9 1.1 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ37667.1 - 7.1 5.3 12.9 6.9 5.4 12.9 1.1 1 0 0 1 1 1 0 Androgen receptor SNARE_assoc PF09335.11 CDJ37668.1 - 1.9e-17 63.9 7.9 1.9e-17 63.9 7.9 2.7 3 1 0 3 3 3 1 SNARE associated Golgi protein DUF2407_C PF13373.6 CDJ37668.1 - 0.083 13.1 0.0 0.26 11.4 0.0 2.0 1 1 0 1 1 1 0 DUF2407 C-terminal domain Baculo_11_kDa PF06143.11 CDJ37668.1 - 0.13 11.9 0.5 0.5 10.0 0.5 2.0 1 0 0 1 1 1 0 Baculovirus 11 kDa family Androgen_recep PF02166.16 CDJ37668.1 - 4.6 6.0 7.5 6.7 5.4 7.5 1.1 1 0 0 1 1 1 0 Androgen receptor DUF2722 PF10846.8 CDJ37669.1 - 0.031 13.2 75.4 0.022 13.7 13.2 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) CBFD_NFYB_HMF PF00808.23 CDJ37671.1 - 1.2e-05 25.4 0.6 3.6e-05 24.0 0.6 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ37671.1 - 3.2e-05 24.3 0.4 3.2e-05 24.3 0.4 2.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF2722 PF10846.8 CDJ37671.1 - 0.0013 17.8 2.6 0.0013 17.8 2.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DUF4718 PF15842.5 CDJ37671.1 - 0.0018 18.1 0.9 0.0018 18.1 0.9 1.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4718) TFIIA PF03153.13 CDJ37671.1 - 0.019 15.0 14.8 0.026 14.5 14.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rxt3 PF08642.10 CDJ37671.1 - 0.06 14.1 1.2 0.08 13.7 0.3 1.7 2 0 0 2 2 1 0 Histone deacetylation protein Rxt3 DUF31 PF01732.16 CDJ37671.1 - 0.065 12.8 0.1 0.094 12.2 0.1 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF31) MarC PF01914.17 CDJ37671.1 - 0.22 10.9 1.7 0.27 10.6 0.6 1.6 2 0 0 2 2 2 0 MarC family integral membrane protein DUF1266 PF06889.11 CDJ37671.1 - 2.2 8.3 7.1 0.91 9.5 3.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Neur_chan_memb PF02932.16 CDJ37671.1 - 3.8 7.5 4.9 6 6.8 4.9 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MTBP_C PF14920.6 CDJ37671.1 - 5 6.8 11.2 0.57 9.9 7.3 1.4 2 0 0 2 2 2 0 MDM2-binding Cytochrom_B_C PF00032.17 CDJ37672.1 - 0.093 13.0 0.5 0.13 12.6 0.5 1.2 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD RNA_pol_L_2 PF13656.6 CDJ37673.1 - 4.2e-19 68.1 0.0 4.9e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CDJ37673.1 - 0.00042 19.7 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF515 PF04415.12 CDJ37673.1 - 1.9 6.8 7.3 1.9 6.8 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF3446 PF11928.8 CDJ37673.1 - 5.3 7.4 20.5 2.1 8.7 18.2 1.6 2 0 0 2 2 2 0 Early growth response N-terminal domain IGPS PF00218.21 CDJ37674.1 - 5.8e-08 32.2 1.7 5.8e-08 32.2 1.7 2.8 2 1 1 3 3 3 1 Indole-3-glycerol phosphate synthase SUIM_assoc PF16619.5 CDJ37674.1 - 0.00084 19.4 3.6 0.00084 19.4 3.6 7.0 4 1 2 6 6 6 1 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ37675.1 - 0.0019 18.5 1.6 0.0019 18.5 1.6 6.7 2 2 1 4 4 4 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ37676.1 - 0.00053 19.7 19.2 0.00053 19.7 19.2 4.9 3 1 1 5 5 5 1 Nuclear RNA-splicing-associated protein tRNA_m1G_MT PF01746.21 CDJ37678.1 - 1.9e-12 47.3 0.0 1.2e-11 44.7 0.0 2.1 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Acyltransferase PF01553.21 CDJ37679.1 - 2.1e-19 69.5 0.0 3.6e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Fumble PF03630.14 CDJ37680.1 - 0.34 10.0 0.7 0.56 9.3 0.7 1.3 1 0 0 1 1 1 0 Fumble Peptidase_M14 PF00246.24 CDJ37681.1 - 0.03 14.1 0.0 0.037 13.8 0.0 1.1 1 0 0 1 1 1 0 Zinc carboxypeptidase GATase PF00117.28 CDJ37682.1 - 6.5e-15 55.4 0.0 7.3e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Chorismate_bind PF00425.18 CDJ37683.1 - 2.3e-30 106.0 0.0 8e-22 78.0 0.0 2.2 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.28 CDJ37683.1 - 1.7e-06 27.9 0.1 3.2e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 CDJ37683.1 - 3.3e-06 27.4 0.9 0.00068 19.9 0.2 3.2 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region DUF1682 PF07946.14 CDJ37685.1 - 4.6e-57 193.7 0.4 5.7e-57 193.3 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DsrC PF04358.13 CDJ37685.1 - 0.053 14.0 0.5 0.53 10.8 0.5 2.3 2 0 0 2 2 2 0 DsrC like protein CRA PF06589.11 CDJ37685.1 - 1.5 8.9 7.2 3.5 7.8 7.2 1.5 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Mito_carr PF00153.27 CDJ37686.1 - 1.2e-26 92.4 3.5 1e-07 31.7 0.1 4.3 3 1 1 4 4 4 4 Mitochondrial carrier protein Lzipper-MIP1 PF14389.6 CDJ37686.1 - 0.036 14.4 3.3 0.037 14.3 0.4 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 TEX13 PF15186.6 CDJ37686.1 - 0.047 13.4 0.7 0.11 12.1 0.7 1.6 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Metallothio PF00131.20 CDJ37686.1 - 0.24 11.5 5.1 0.55 10.4 5.1 1.5 1 0 0 1 1 1 0 Metallothionein DUF4692 PF15763.5 CDJ37686.1 - 0.76 10.2 7.1 0.064 13.7 1.9 1.8 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Sec1 PF00995.23 CDJ37687.1 - 0.013 14.7 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Sec1 family SUIM_assoc PF16619.5 CDJ37689.1 - 0.24 11.5 9.0 0.27 11.3 0.2 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 OTU PF02338.19 CDJ37690.1 - 2e-13 50.9 0.0 5.8e-13 49.5 0.0 1.7 1 1 1 2 2 2 1 OTU-like cysteine protease DUF2391 PF09622.10 CDJ37691.1 - 0.058 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) PTPlike_phytase PF14566.6 CDJ37691.1 - 1.3 9.1 5.9 4.1 7.5 5.9 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate Connexin PF00029.19 CDJ37691.1 - 3.6 7.3 5.4 4.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Connexin Motilin_assoc PF04643.12 CDJ37692.1 - 0.43 10.5 2.7 1.3 8.9 2.7 1.8 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide APG6 PF04111.12 CDJ37694.1 - 5.5e-46 156.8 0.0 8.8e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 CDJ37694.1 - 2.2e-12 47.7 8.3 3.3e-12 47.1 8.3 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Lectin_N PF03954.14 CDJ37694.1 - 0.017 14.9 1.2 0.032 14.0 1.2 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF4164 PF13747.6 CDJ37694.1 - 0.044 14.1 7.6 0.11 12.8 7.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF4407 PF14362.6 CDJ37694.1 - 0.065 12.6 0.0 0.094 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Swi5 PF07061.11 CDJ37694.1 - 0.46 10.6 3.3 0.95 9.6 3.3 1.5 1 0 0 1 1 1 0 Swi5 TMF_DNA_bd PF12329.8 CDJ37694.1 - 0.85 9.7 8.9 0.62 10.1 6.5 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 CDJ37694.1 - 1.1 9.0 4.4 2.4 8.0 4.4 1.4 1 0 0 1 1 1 0 Septum formation initiator UQ_con PF00179.26 CDJ37696.1 - 2.8e-51 172.9 0.0 3.4e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ37696.1 - 0.0002 21.1 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ37696.1 - 0.054 13.8 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Ank_2 PF12796.7 CDJ37697.1 - 4.1e-31 107.4 5.3 2e-09 37.9 0.4 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ37697.1 - 2.9e-24 85.1 1.3 4.5e-09 36.7 0.0 5.7 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ37697.1 - 8.6e-24 83.3 6.9 6.7e-06 26.3 0.0 6.1 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ37697.1 - 3.8e-23 79.0 3.8 0.015 15.8 0.0 7.8 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 CDJ37697.1 - 3.2e-20 71.6 15.4 0.015 15.8 0.0 7.4 8 0 0 8 8 8 5 Ankyrin repeat TPR_11 PF13414.6 CDJ37697.1 - 0.049 13.3 0.1 14 5.4 0.0 3.7 3 1 0 3 3 3 0 TPR repeat TPR_2 PF07719.17 CDJ37697.1 - 0.063 13.4 0.4 9.7 6.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ37697.1 - 0.067 13.6 0.0 13 6.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ37697.1 - 0.42 11.6 6.6 6.8 7.8 0.2 4.1 2 2 1 3 3 3 0 Tetratricopeptide repeat Ribosomal_S15 PF00312.22 CDJ37698.1 - 1.5e-22 79.6 2.5 2.5e-22 78.9 2.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 zf-RING_2 PF13639.6 CDJ37700.1 - 9.7e-09 35.4 9.8 6.1e-08 32.9 3.4 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ37700.1 - 1.9e-07 30.8 6.6 3e-07 30.2 2.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ37700.1 - 3e-07 30.3 7.4 3.1e-07 30.3 1.2 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDJ37700.1 - 7.6e-06 25.7 7.9 9.1e-06 25.4 2.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ37700.1 - 1.3e-05 24.9 8.3 1.7e-05 24.6 1.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ37700.1 - 1.6e-05 25.1 1.3 1.6e-05 25.1 1.3 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CDJ37700.1 - 5.3e-05 23.0 6.1 0.00038 20.2 1.5 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CDJ37700.1 - 0.00024 21.1 2.5 0.00024 21.1 2.5 2.9 2 1 0 2 2 2 1 RING-type zinc-finger PRIMA1 PF16101.5 CDJ37700.1 - 1.1 9.3 8.1 3.9 7.5 8.1 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-Nse PF11789.8 CDJ37700.1 - 1.7 8.5 4.2 0.86 9.5 1.3 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 CDJ37700.1 - 1.8 8.6 4.1 0.43 10.7 0.3 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CDJ37700.1 - 2.1 8.2 6.4 2.8 7.8 0.6 3.0 3 0 0 3 3 3 0 RING-like zinc finger zf-P11 PF03854.14 CDJ37700.1 - 3.3 7.4 7.5 0.35 10.6 2.1 2.0 2 0 0 2 2 2 0 P-11 zinc finger eIF-3_zeta PF05091.12 CDJ37700.1 - 8.9 5.2 13.6 14 4.5 13.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SPRY PF00622.28 CDJ37701.1 - 4.9e-06 26.7 0.0 0.0051 16.9 0.0 3.3 2 0 0 2 2 2 2 SPRY domain Rad21_Rec8 PF04824.16 CDJ37702.1 - 1.6e-05 24.1 0.0 4.8e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Peptidase_S8 PF00082.22 CDJ37702.1 - 0.47 9.7 5.1 1 8.6 5.1 1.6 1 0 0 1 1 1 0 Subtilase family DUF4168 PF13767.6 CDJ37703.1 - 0.14 13.3 0.0 0.29 12.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) Actin PF00022.19 CDJ37705.1 - 3.9e-26 91.6 0.0 3.4e-22 78.6 0.0 2.8 2 1 0 2 2 2 2 Actin TraW_N PF12477.8 CDJ37705.1 - 0.1 12.6 1.3 0.3 11.1 1.3 1.9 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal zf-CCHC PF00098.23 CDJ37706.1 - 2.8e-05 24.0 9.3 0.0018 18.3 1.2 2.5 2 0 0 2 2 2 2 Zinc knuckle Retrotrans_gag PF03732.17 CDJ37706.1 - 0.0042 17.3 0.1 0.023 15.0 0.0 2.2 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC_6 PF15288.6 CDJ37706.1 - 0.098 12.5 0.4 0.098 12.5 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle PPR_2 PF13041.6 CDJ37707.1 - 2.5e-11 43.6 0.0 2.4e-09 37.2 0.0 2.3 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 CDJ37707.1 - 7.9e-08 32.0 2.6 0.14 12.4 0.0 4.2 4 0 0 4 4 4 3 PPR repeat PPR_1 PF12854.7 CDJ37707.1 - 3.7e-07 29.7 0.1 0.017 14.8 0.0 2.5 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.6 CDJ37707.1 - 2.3e-05 24.4 0.0 4.9e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 CDJ37708.1 - 1.4e-31 108.4 0.3 1.5e-15 57.1 0.0 3.3 1 1 2 3 3 3 3 PPR repeat family PPR_1 PF12854.7 CDJ37708.1 - 7.2e-21 73.6 1.3 9.8e-09 34.8 0.0 3.8 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 CDJ37708.1 - 6.2e-20 71.0 0.0 6.3e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 CDJ37708.1 - 1.2e-19 69.1 1.1 2.7e-06 27.2 0.0 4.4 4 1 0 4 4 4 3 PPR repeat PPR_long PF17177.4 CDJ37708.1 - 1.5e-11 44.1 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP HOOK PF05622.12 CDJ37709.1 - 0.00098 17.4 11.2 0.00098 17.4 11.2 10.7 7 3 3 10 10 10 3 HOOK protein DivIC PF04977.15 CDJ37709.1 - 0.0034 17.1 4.6 0.0034 17.1 4.6 20.6 18 3 4 23 23 23 3 Septum formation initiator RILP PF11461.8 CDJ37709.1 - 0.0044 17.2 36.4 0.34 11.1 0.0 9.0 8 0 0 8 8 8 3 Rab interacting lysosomal protein DUF3164 PF11363.8 CDJ37709.1 - 0.65 9.6 11.4 4.3 6.9 2.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3164) DUF3287 PF11690.8 CDJ37709.1 - 8.5 6.1 9.3 5.2 6.8 0.6 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3287) 2TM PF13239.6 CDJ37710.1 - 0.28 11.5 0.0 0.28 11.5 0.0 3.8 3 2 1 4 4 4 0 2TM domain Metallophos PF00149.28 CDJ37711.1 - 2.4e-05 24.9 0.0 0.0036 17.8 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ37711.1 - 0.0054 16.9 0.0 1.5 9.0 0.0 3.1 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_67N PF03648.14 CDJ37712.1 - 0.0042 17.4 0.4 0.01 16.1 0.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus PUB PF09409.10 CDJ37713.1 - 1.7e-24 85.5 0.0 4.9e-24 84.1 0.0 1.7 2 0 0 2 2 2 1 PUB domain UBA PF00627.31 CDJ37713.1 - 0.0011 18.9 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Myosin_TH1 PF06017.13 CDJ37713.1 - 0.062 13.0 0.3 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding Asp-B-Hydro_N PF05279.11 CDJ37713.1 - 0.84 9.7 9.9 1.4 8.9 9.9 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MCM3AP_GANP PF16769.5 CDJ37713.1 - 1.4 7.1 9.4 2.1 6.5 9.4 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP MAJIN PF15077.6 CDJ37713.1 - 1.5 8.5 7.2 2.7 7.7 7.2 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein V_ATPase_I PF01496.19 CDJ37713.1 - 2.3 6.0 5.3 2.9 5.7 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5401 PF17380.2 CDJ37713.1 - 5.8 4.8 21.4 8.1 4.4 21.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) ArfGap PF01412.18 CDJ37714.1 - 2.5e-28 98.5 0.0 5.2e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Peptidase_M18 PF02127.15 CDJ37715.1 - 1e-131 439.7 0.0 4e-131 437.8 0.0 1.7 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CDJ37715.1 - 0.00061 18.9 0.0 0.0022 17.1 0.0 1.8 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Sec23_trunk PF04811.15 CDJ37716.1 - 1.7e-20 73.6 1.6 3.5e-20 72.6 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CDJ37716.1 - 8.3e-17 60.9 0.4 3.7e-16 58.8 0.4 2.3 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CDJ37716.1 - 4.1e-10 39.5 5.1 8.5e-10 38.5 5.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CDJ37716.1 - 3.6e-08 34.0 0.0 2.1e-07 31.6 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain WD40 PF00400.32 CDJ37717.1 - 5.8e-10 39.6 6.9 0.22 12.5 0.0 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat OmpH PF03938.14 CDJ37717.1 - 0.017 15.4 2.6 0.031 14.6 2.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4376 PF14301.6 CDJ37717.1 - 0.12 12.8 0.5 0.41 11.0 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) Metal_resist PF13801.6 CDJ37717.1 - 0.15 12.2 8.1 0.4 10.9 8.1 1.6 1 0 0 1 1 1 0 Heavy-metal resistance UPF0242 PF06785.11 CDJ37717.1 - 0.29 11.2 1.9 0.48 10.5 1.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus POTRA_TamA_1 PF17243.2 CDJ37717.1 - 0.65 10.1 3.3 1.7 8.8 3.3 1.7 1 0 0 1 1 1 0 POTRA domain TamA domain 1 HECT PF00632.25 CDJ37718.1 - 4.8e-30 105.1 0.0 7.5e-27 94.6 0.0 2.2 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) AKAP7_NLS PF10469.9 CDJ37719.1 - 6.4e-38 130.7 0.1 1.1e-37 130.0 0.1 1.4 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 CDJ37719.1 - 0.00013 21.9 0.5 0.00037 20.4 0.4 1.8 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily Inositol_P PF00459.25 CDJ37720.1 - 1.7e-16 60.6 0.4 7.1e-06 25.7 0.0 4.1 3 1 1 4 4 4 3 Inositol monophosphatase family SUIM_assoc PF16619.5 CDJ37720.1 - 0.00019 21.4 9.8 4.4 7.4 0.0 4.9 3 1 1 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 Cons_hypoth95 PF03602.15 CDJ37721.1 - 8.5e-36 123.3 0.0 1e-34 119.8 0.0 2.2 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 CDJ37721.1 - 7.3e-07 29.1 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ37721.1 - 0.00094 19.8 0.0 0.0038 17.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CDJ37721.1 - 0.0029 17.2 0.1 0.026 14.1 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase small domain PrmA PF06325.13 CDJ37721.1 - 0.0035 16.8 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 CDJ37721.1 - 0.25 10.9 0.0 0.45 10.1 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ABM PF03992.16 CDJ37722.1 - 0.005 16.9 0.1 0.033 14.3 0.0 2.4 1 1 1 2 2 2 1 Antibiotic biosynthesis monooxygenase TnpV PF14198.6 CDJ37722.1 - 0.51 10.3 3.8 0.76 9.8 3.8 1.2 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Pyr_redox_2 PF07992.14 CDJ37724.1 - 5.6e-16 58.6 0.0 1.5e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AIRS_C PF02769.22 CDJ37724.1 - 7.4e-15 55.4 3.9 9.6e-11 42.0 2.3 2.6 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.24 CDJ37724.1 - 6.6e-11 42.7 0.2 4e-10 40.2 0.2 2.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Pyr_redox PF00070.27 CDJ37724.1 - 3.5e-08 33.9 0.6 0.0034 17.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase UCR_TM PF02921.14 CDJ37724.1 - 0.013 15.9 0.0 0.042 14.3 0.0 1.9 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region Pyr_redox_3 PF13738.6 CDJ37724.1 - 0.037 13.3 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1635 PF07795.11 CDJ37724.1 - 0.18 11.7 4.0 3 7.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DHHC PF01529.20 CDJ37725.1 - 6.9e-11 42.4 9.2 1.3e-10 41.4 9.2 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase RabGAP-TBC PF00566.18 CDJ37726.1 - 1.4e-40 139.2 0.1 1.4e-40 139.2 0.1 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain F-box PF00646.33 CDJ37726.1 - 0.00044 20.0 0.5 0.001 18.9 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDJ37726.1 - 0.0021 17.9 0.7 0.0061 16.4 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 CDJ37726.1 - 0.045 13.3 0.9 0.1 12.2 0.9 1.6 1 0 0 1 1 1 0 F-box Presenilin PF01080.17 CDJ37726.1 - 3.2 6.4 4.5 4.6 5.9 4.5 1.1 1 0 0 1 1 1 0 Presenilin CDC73_N PF16050.5 CDJ37727.1 - 0.014 14.7 3.6 0.021 14.1 3.6 1.2 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal DUF3464 PF11947.8 CDJ37727.1 - 0.64 9.8 3.8 1.2 8.9 3.8 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4810 PF16068.5 CDJ37727.1 - 2.9 8.5 8.1 0.29 11.7 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4810) Presenilin PF01080.17 CDJ37727.1 - 3 6.5 5.1 4.1 6.0 5.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ37727.1 - 3.5 8.6 5.6 7.4 7.6 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Rhodanese PF00581.20 CDJ37728.1 - 2.5e-17 63.4 0.0 5.5e-05 23.7 0.0 4.2 3 1 0 3 3 3 3 Rhodanese-like domain TFIIA PF03153.13 CDJ37728.1 - 0.0083 16.2 10.2 0.016 15.2 1.6 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.6 CDJ37728.1 - 0.036 14.6 0.2 8 6.9 0.9 2.2 2 0 0 2 2 2 0 AAA domain DUF2722 PF10846.8 CDJ37728.1 - 0.047 12.6 3.9 0.62 8.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spc24 PF08286.11 CDJ37728.1 - 0.07 13.4 0.7 0.07 13.4 0.7 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SPT16 PF08644.11 CDJ37728.1 - 1.7 8.8 6.7 0.16 12.2 1.0 1.9 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) SNase PF00565.17 CDJ37729.1 - 8.6e-09 35.8 0.0 4.1e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Staphylococcal nuclease homologue YopE_N PF09020.10 CDJ37729.1 - 0.2 11.9 0.9 59 3.9 0.0 3.2 3 0 0 3 3 3 0 YopE, N terminal RRM_1 PF00076.22 CDJ37730.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Endonuclease_NS PF01223.23 CDJ37731.1 - 5.4e-06 26.4 0.0 0.057 13.2 0.0 2.1 2 0 0 2 2 2 2 DNA/RNA non-specific endonuclease Endonuclease_NS PF01223.23 CDJ37732.1 - 7.2e-05 22.7 0.0 0.32 10.8 0.0 2.1 1 1 0 2 2 2 2 DNA/RNA non-specific endonuclease Endonuclease_NS PF01223.23 CDJ37734.1 - 1.8e-05 24.7 0.0 0.003 17.4 0.0 3.5 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease MDFI PF15316.6 CDJ37736.1 - 0.0049 17.0 8.0 0.0049 17.0 8.0 3.6 4 1 1 5 5 5 1 MyoD family inhibitor AdoHcyase PF05221.17 CDJ37737.1 - 3e-136 453.4 0.0 3.4e-136 453.2 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CDJ37737.1 - 2.6e-81 271.4 1.3 3.6e-81 271.0 1.3 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CDJ37737.1 - 1.9e-06 27.3 0.1 3.5e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CDJ37737.1 - 0.00056 19.5 0.1 0.001 18.7 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CDJ37737.1 - 0.0022 18.2 0.1 0.005 17.1 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.19 CDJ37737.1 - 0.047 13.0 1.0 0.52 9.6 0.9 2.6 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 CDJ37737.1 - 0.089 12.8 0.1 0.23 11.5 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltrn_RNA_3 PF02598.17 CDJ37738.1 - 3.6e-72 243.3 0.0 6.5e-26 91.5 0.0 3.2 2 1 1 3 3 3 3 Putative RNA methyltransferase MRP-S34 PF16053.5 CDJ37738.1 - 1.4 8.6 6.8 6.5 6.4 4.5 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S34 BTB_2 PF02214.22 CDJ37739.1 - 0.00016 21.9 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-CCCH PF00642.24 CDJ37739.1 - 0.0032 17.3 2.8 0.0032 17.3 2.8 3.2 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) EH_Signature PF15611.6 CDJ37739.1 - 0.0035 16.8 0.3 0.0035 16.8 0.3 2.0 2 0 0 2 2 2 1 EH_Signature domain zf_CCCH_4 PF18345.1 CDJ37739.1 - 0.0047 16.9 6.6 0.0047 16.9 6.6 3.4 2 1 0 2 2 2 1 Zinc finger domain CDC45 PF02724.14 CDJ37739.1 - 0.012 13.9 8.4 0.022 13.0 8.4 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 CDJ37739.1 - 0.12 12.3 49.3 0.05 13.6 29.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 CDJ37739.1 - 0.17 12.2 10.3 0.56 10.6 10.1 1.9 2 0 0 2 2 2 0 Enhancer of polycomb-like Otopetrin PF03189.13 CDJ37739.1 - 0.89 8.3 2.6 1.4 7.6 2.6 1.2 1 0 0 1 1 1 0 Otopetrin SOBP PF15279.6 CDJ37739.1 - 1.2 9.6 23.4 4.3 7.9 11.1 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein SARG PF15385.6 CDJ37739.1 - 1.4 8.1 32.2 0.024 13.9 16.8 2.3 2 0 0 2 2 2 0 Specifically androgen-regulated gene protein DUF1387 PF07139.11 CDJ37739.1 - 4.5 6.9 26.5 0.045 13.5 14.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) RR_TM4-6 PF06459.12 CDJ37739.1 - 5.4 6.8 18.9 11 5.7 18.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Senescence_reg PF04520.13 CDJ37739.1 - 7.9 7.3 21.8 5.9 7.7 12.6 2.5 2 0 0 2 2 2 0 Senescence regulator DDHD PF02862.17 CDJ37739.1 - 8.6 6.4 13.1 0.26 11.4 5.8 2.0 2 0 0 2 2 2 0 DDHD domain Zip PF02535.22 CDJ37741.1 - 0.82 8.8 3.6 0.52 9.5 1.9 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter DUF572 PF04502.13 CDJ37741.1 - 1.9 8.1 16.2 0.7 9.5 9.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF2052 PF09747.9 CDJ37741.1 - 7.9 6.6 16.6 11 6.1 1.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) HSP20 PF00011.21 CDJ37742.1 - 7.9e-11 42.0 0.0 1.5e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ37742.1 - 0.0002 20.8 0.0 0.00084 18.8 0.0 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HMG_box PF00505.19 CDJ37743.1 - 4.8e-22 78.2 5.0 7.7e-22 77.5 5.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ37743.1 - 1.6e-15 57.4 4.2 2.6e-15 56.7 4.2 1.3 1 0 0 1 1 1 1 HMG-box domain KRAB PF01352.27 CDJ37743.1 - 0.027 14.1 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 KRAB box Peptidase_C14 PF00656.22 CDJ37744.1 - 3.7e-12 46.7 0.2 1.7e-11 44.6 0.0 2.3 2 0 0 2 2 2 1 Caspase domain DUF3377 PF11857.8 CDJ37744.1 - 4.9 7.2 5.1 12 5.9 5.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) 4HBT PF03061.22 CDJ37745.1 - 0.0015 18.8 0.6 0.0015 18.8 0.6 2.4 3 0 0 3 3 3 1 Thioesterase superfamily RRM PF10378.9 CDJ37746.1 - 0.028 14.1 1.2 0.028 14.1 1.2 3.8 4 0 0 4 4 4 0 Putative RRM domain SUIM_assoc PF16619.5 CDJ37746.1 - 0.042 13.9 32.1 0.064 13.3 0.2 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TraT PF05818.12 CDJ37746.1 - 0.055 13.1 14.0 0.099 12.3 11.3 2.0 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein DUF1442 PF07279.11 CDJ37746.1 - 0.06 12.6 1.1 0.095 12.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) Dehydrin PF00257.19 CDJ37746.1 - 0.092 13.3 8.4 0.11 13.0 4.1 2.2 2 0 0 2 2 2 0 Dehydrin DUF677 PF05055.12 CDJ37746.1 - 1.5 7.6 4.7 2.5 6.9 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) PP2C_2 PF13672.6 CDJ37746.1 - 5.2 6.6 15.3 1.7 8.2 11.3 1.9 1 1 1 2 2 2 0 Protein phosphatase 2C RskA PF10099.9 CDJ37747.1 - 0.3 11.4 0.0 0.3 11.4 0.0 10.9 2 2 5 7 7 7 0 Anti-sigma-K factor rskA Peptidase_S64 PF08192.11 CDJ37748.1 - 0.25 9.8 21.5 0.53 8.7 21.5 1.5 1 0 0 1 1 1 0 Peptidase family S64 Abhydro_lipase PF04083.16 CDJ37749.1 - 0.0063 16.1 0.1 0.018 14.6 0.1 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region DUF4834 PF16118.5 CDJ37750.1 - 1.8 9.6 19.2 20 6.3 2.6 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) SR-25 PF10500.9 CDJ37751.1 - 0.00062 19.4 5.5 0.00062 19.4 5.5 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein FAM199X PF15814.5 CDJ37751.1 - 2.4 7.1 11.4 4.1 6.4 11.4 1.3 1 0 0 1 1 1 0 Protein family FAM199X MMS1_N PF10433.9 CDJ37753.1 - 7.7e-20 71.0 0.1 7.2e-19 67.8 0.0 2.3 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CDJ37753.1 - 7.9e-17 61.5 0.0 1.4e-10 41.0 0.0 3.4 4 0 0 4 4 4 2 CPSF A subunit region SR-25 PF10500.9 CDJ37753.1 - 9.1e-05 22.2 11.1 9.1e-05 22.2 11.1 10.2 12 0 0 12 12 12 4 Nuclear RNA-splicing-associated protein EPL1 PF10513.9 CDJ37753.1 - 2.6 8.4 5.5 5.1 7.5 0.1 3.4 3 0 0 3 3 3 0 Enhancer of polycomb-like Coilin_N PF15862.5 CDJ37753.1 - 8.9 6.1 13.6 0.88 9.4 0.4 4.0 4 0 0 4 4 4 0 Coilin N-terminus MAR_sialic_bdg PF10564.9 CDJ37754.1 - 8e-47 157.2 13.4 6.8e-17 61.3 1.8 3.2 3 0 0 3 3 3 3 Sialic-acid binding micronemal adhesive repeat DUF2520 PF10728.9 CDJ37754.1 - 0.0099 15.6 0.0 0.36 10.6 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF2520) MAR_sialic_bdg PF10564.9 CDJ37755.1 - 1.7e-47 159.4 22.1 3.5e-16 59.0 1.5 4.3 4 0 0 4 4 4 4 Sialic-acid binding micronemal adhesive repeat DUF2520 PF10728.9 CDJ37755.1 - 0.023 14.4 0.0 6 6.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2520) zf-B_box PF00643.24 CDJ37755.1 - 0.28 11.4 4.4 1.1 9.5 4.4 2.1 1 0 0 1 1 1 0 B-box zinc finger Caskin1-CID PF16600.5 CDJ37756.1 - 0.077 13.6 1.9 0.086 13.4 0.3 2.0 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain DUF913 PF06025.12 CDJ37757.1 - 0.092 11.7 0.7 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Pkinase PF00069.25 CDJ37758.1 - 7.7e-32 110.7 2.2 4.6e-17 62.3 0.0 4.1 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37758.1 - 5.3e-14 52.1 0.0 6.2e-08 32.2 0.0 3.6 3 1 0 3 3 3 3 Protein tyrosine kinase His_Phos_2 PF00328.22 CDJ37759.1 - 0.013 14.9 0.0 4.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) SUIM_assoc PF16619.5 CDJ37759.1 - 0.5 10.5 22.2 1.3 9.1 2.0 3.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF678 PF05077.12 CDJ37761.1 - 0.31 11.2 1.1 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Pkinase PF00069.25 CDJ37763.1 - 2.7e-32 112.2 0.0 4.1e-28 98.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37763.1 - 2.3e-26 92.7 0.0 6.8e-22 78.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Protamine_P2 PF00841.19 CDJ37764.1 - 0.61 10.6 4.5 1.2 9.7 4.5 1.5 1 0 0 1 1 1 0 Sperm histone P2 TFIIA PF03153.13 CDJ37764.1 - 0.62 10.0 17.3 0.88 9.5 17.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAP70 PF07058.11 CDJ37764.1 - 0.72 8.5 5.8 0.82 8.3 5.8 1.0 1 0 0 1 1 1 0 Microtubule-associated protein 70 Lin-8 PF03353.15 CDJ37764.1 - 1.7 8.1 6.5 2 7.9 6.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ37764.1 - 2.4 6.6 8.0 2.7 6.4 8.0 1.0 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 CDJ37764.1 - 8.7 5.2 7.9 9.9 5.0 7.9 1.1 1 0 0 1 1 1 0 Mitoguardin FapA PF03961.13 CDJ37765.1 - 0.48 9.0 1.5 0.81 8.2 1.5 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Unstab_antitox PF09720.10 CDJ37765.1 - 0.85 9.7 10.9 2.8 8.1 2.4 3.7 3 0 0 3 3 3 0 Putative addiction module component MutS_II PF05188.17 CDJ37765.1 - 1.7 8.9 5.5 0.63 10.3 1.2 2.3 2 0 0 2 2 2 0 MutS domain II Paralemmin PF03285.15 CDJ37765.1 - 7.3 6.1 8.8 0.49 9.9 3.0 2.0 2 0 0 2 2 2 0 Paralemmin Mito_morph_reg PF14972.6 CDJ37766.1 - 0.046 13.3 1.4 0.1 12.2 1.4 1.5 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator AF-4 PF05110.13 CDJ37766.1 - 0.44 8.6 6.3 0.67 8.0 6.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 CDJ37766.1 - 0.62 9.6 11.9 0.041 13.5 6.9 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4719 PF15843.5 CDJ37766.1 - 0.91 9.6 6.7 0.28 11.3 3.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) FBP_C PF16571.5 CDJ37767.1 - 0.077 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger Pkinase PF00069.25 CDJ37768.1 - 1e-11 44.7 0.0 3e-05 23.5 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37768.1 - 0.013 14.8 0.0 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase WSD PF15613.6 CDJ37769.1 - 0.0003 21.2 0.0 0.0003 21.2 0.0 5.5 5 2 0 5 5 5 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Auxin_resp PF06507.13 CDJ37769.1 - 0.0007 19.8 0.0 0.0025 18.0 0.0 1.9 2 0 0 2 2 2 1 Auxin response factor DNMT1-RFD PF12047.8 CDJ37769.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain DDT PF02791.17 CDJ37769.1 - 0.15 12.4 0.0 0.56 10.6 0.0 1.9 1 0 0 1 1 1 0 DDT domain HECT PF00632.25 CDJ37770.1 - 1.5e-82 277.5 0.0 2.1e-82 277.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PALP PF00291.25 CDJ37771.1 - 5.7e-47 160.5 0.0 1e-46 159.7 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SPX PF03105.19 CDJ37775.1 - 0.0034 17.4 7.8 0.0034 17.4 7.8 3.3 3 1 0 3 3 3 1 SPX domain TFIIA PF03153.13 CDJ37775.1 - 9.6 6.1 63.7 0.024 14.6 38.3 3.2 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MTES_1575 PF18741.1 CDJ37777.1 - 0.046 13.9 0.0 0.2 11.9 0.0 2.1 1 0 0 1 1 1 0 REase_MTES_1575 SNAP PF14938.6 CDJ37778.1 - 6.1e-52 176.8 26.4 1.8e-28 99.8 3.3 2.8 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP PGM_PMM_III PF02880.16 CDJ37778.1 - 0.013 15.6 0.0 0.039 14.1 0.0 1.8 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Med15 PF09606.10 CDJ37778.1 - 0.035 12.8 11.4 0.0098 14.6 3.5 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal MAGI_u5 PF16666.5 CDJ37778.1 - 2.2 8.4 11.7 6 7.0 11.7 1.6 1 0 0 1 1 1 0 Unstructured region on MAGI Spt20 PF12090.8 CDJ37778.1 - 8.7 5.9 13.2 7.7 6.1 5.9 2.3 2 0 0 2 2 2 0 Spt20 family Glyco_transf_20 PF00982.21 CDJ37779.1 - 6.2e-61 206.5 0.0 6.2e-61 206.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CDJ37779.1 - 3e-50 170.5 0.0 3.3e-49 167.1 0.0 2.2 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 CDJ37779.1 - 6.7e-05 22.8 0.3 0.00089 19.1 0.0 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase RR_TM4-6 PF06459.12 CDJ37779.1 - 0.14 12.0 8.6 0.22 11.3 8.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCT PF06203.14 CDJ37779.1 - 0.15 12.1 0.2 0.42 10.7 0.2 1.7 1 0 0 1 1 1 0 CCT motif Vac7 PF12751.7 CDJ37779.1 - 0.22 10.9 3.6 0.32 10.4 3.6 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 PA26 PF04636.13 CDJ37779.1 - 0.35 9.7 7.4 1.4 7.8 6.8 1.9 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) ECM1 PF05782.11 CDJ37779.1 - 4.4 6.1 15.3 6.8 5.5 15.3 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Methyltr_RsmB-F PF01189.17 CDJ37781.1 - 4.2e-12 46.1 1.1 9.1e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Spt20 PF12090.8 CDJ37781.1 - 0.01 15.5 8.4 0.01 15.5 8.4 2.4 2 1 0 2 2 2 0 Spt20 family PSK PF06404.12 CDJ37781.1 - 0.027 15.5 2.6 0.027 15.5 2.6 3.6 5 0 0 5 5 5 0 Phytosulfokine precursor protein (PSK) RAWUL PF16207.5 CDJ37781.1 - 0.17 12.5 0.4 0.32 11.7 0.4 1.3 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like DUF3381 PF11861.8 CDJ37781.1 - 0.25 11.1 9.0 0.057 13.2 5.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 CDJ37781.1 - 1.4 8.8 4.6 2.6 7.9 4.2 1.5 1 1 0 1 1 1 0 Methyltransferase domain RuvX PF03652.15 CDJ37783.1 - 2.6e-12 47.3 0.0 5.6e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 Holliday junction resolvase Pex2_Pex12 PF04757.14 CDJ37784.1 - 1.6e-20 73.7 7.0 3.2e-20 72.7 7.0 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 CDJ37784.1 - 0.08 12.9 6.1 0.14 12.1 5.4 1.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H PF13771.6 CDJ37784.1 - 0.13 12.6 2.5 0.44 10.8 2.5 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain Connexin PF00029.19 CDJ37784.1 - 0.14 11.9 5.6 0.049 13.4 1.0 2.2 2 0 0 2 2 2 0 Connexin zf-C3HC4_3 PF13920.6 CDJ37784.1 - 0.22 11.4 9.1 0.72 9.8 9.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tim54 PF11711.8 CDJ37784.1 - 1 8.1 8.6 0.62 8.8 1.8 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Mg_trans_NIPA PF05653.14 CDJ37785.1 - 3.9e-10 39.3 13.4 1.2e-08 34.4 0.6 2.5 3 0 0 3 3 3 2 Magnesium transporter NIPA SAYSvFN PF10260.9 CDJ37789.1 - 7.1e-12 45.1 0.1 1e-11 44.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) SEC-C PF02810.15 CDJ37789.1 - 0.0012 18.8 5.6 0.0018 18.2 5.6 1.3 1 0 0 1 1 1 1 SEC-C motif Symplekin_C PF12295.8 CDJ37789.1 - 0.13 12.4 0.2 0.17 11.9 0.2 1.1 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal Pepsin-I3 PF06394.13 CDJ37790.1 - 0.00016 21.8 6.4 0.31 11.3 0.0 4.0 3 1 1 4 4 4 1 Pepsin inhibitor-3-like repeated domain Sterile PF03015.19 CDJ37790.1 - 0.00097 19.3 1.0 1.2 9.4 0.3 3.2 1 1 1 2 2 2 2 Male sterility protein KNOX1 PF03790.13 CDJ37790.1 - 0.013 15.2 0.0 35 4.2 0.0 3.4 3 0 0 3 3 3 0 KNOX1 domain DehI PF10778.9 CDJ37790.1 - 0.066 13.3 2.3 40 4.3 0.0 3.4 3 0 0 3 3 3 0 Halocarboxylic acid dehydrogenase DehI PepSY_like PF11396.8 CDJ37790.1 - 0.089 13.4 0.2 59 4.3 0.0 3.0 3 0 0 3 3 3 0 Putative beta-lactamase-inhibitor-like, PepSY-like LHH PF14411.6 CDJ37790.1 - 0.19 11.9 1.2 80 3.5 0.0 3.0 3 0 0 3 3 3 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH TraA PF05513.11 CDJ37790.1 - 0.28 11.5 2.4 12 6.3 0.1 3.4 3 1 1 4 4 4 0 TraA Flavi_M PF01004.19 CDJ37790.1 - 0.33 10.7 2.4 16 5.3 0.1 2.9 3 0 0 3 3 3 0 Flavivirus envelope glycoprotein M KH_8 PF17903.1 CDJ37791.1 - 1.6e-33 114.6 0.2 4.1e-33 113.3 0.2 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain Neisseria_TspB PF05616.13 CDJ37791.1 - 3.3 6.1 15.0 5 5.5 15.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein TGT PF01702.18 CDJ37792.1 - 3.9e-09 36.1 0.5 5.4e-07 29.1 0.1 2.1 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase RNA_pol_Rpc4 PF05132.14 CDJ37792.1 - 4.4 7.7 6.5 0.69 10.3 1.5 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 RabGAP-TBC PF00566.18 CDJ37794.1 - 0.0011 18.7 0.9 0.014 15.0 0.6 4.8 4 1 1 5 5 5 3 Rab-GTPase-TBC domain UCH PF00443.29 CDJ37796.1 - 3.5e-35 121.7 0.0 5e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CDJ37796.1 - 1.9e-13 50.5 4.8 3.4e-13 49.7 4.8 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein AF-4 PF05110.13 CDJ37796.1 - 0.00022 19.5 16.4 0.00032 19.0 16.4 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein SPX PF03105.19 CDJ37796.1 - 0.028 14.4 4.9 0.038 13.9 4.9 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 CDJ37796.1 - 0.032 12.8 1.2 0.047 12.3 1.2 1.3 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ37796.1 - 0.043 12.7 2.7 0.059 12.2 2.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 CDJ37796.1 - 0.87 9.1 25.7 1.5 8.3 25.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 CDJ37796.1 - 1.8 8.2 9.5 3.3 7.4 9.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 YbgS PF13985.6 CDJ37796.1 - 3.2 8.1 12.3 6.4 7.1 12.3 1.4 1 0 0 1 1 1 0 YbgS-like protein Hydrolase_4 PF12146.8 CDJ37797.1 - 0.00015 21.2 0.0 0.044 13.0 0.0 2.5 2 0 0 2 2 2 2 Serine aminopeptidase, S33 SPX PF03105.19 CDJ37797.1 - 0.14 12.1 12.8 0.036 14.0 8.4 1.9 2 0 0 2 2 2 0 SPX domain DUF4834 PF16118.5 CDJ37797.1 - 0.65 11.0 12.5 5.4 8.0 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Ctr PF04145.15 CDJ37797.1 - 0.93 10.1 4.4 15 6.2 0.4 3.0 4 0 0 4 4 4 0 Ctr copper transporter family Peroxin-3 PF04882.12 CDJ37797.1 - 0.98 8.3 8.9 7.8 5.4 5.1 2.1 2 0 0 2 2 2 0 Peroxin-3 DUF4131 PF13567.6 CDJ37797.1 - 4.3 7.0 6.9 20 4.8 5.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ORC2 PF04084.14 CDJ37798.1 - 5.8e-37 127.4 0.0 8.4e-21 74.2 0.0 2.3 1 1 1 2 2 2 2 Origin recognition complex subunit 2 DUF755 PF05501.11 CDJ37798.1 - 5.5 7.3 17.8 8 6.8 2.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) adh_short PF00106.25 CDJ37799.1 - 3.5e-15 56.0 0.1 2.2e-14 53.4 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ37799.1 - 2e-13 50.4 0.0 1.3e-11 44.5 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ37799.1 - 0.00025 21.0 0.1 0.00083 19.3 0.1 1.9 2 0 0 2 2 2 1 KR domain DSHCT PF08148.12 CDJ37799.1 - 0.087 12.5 0.0 0.21 11.2 0.0 1.6 1 1 0 1 1 1 0 DSHCT (NUC185) domain Kelch_4 PF13418.6 CDJ37800.1 - 5.4e-19 67.9 5.9 0.00011 22.1 0.0 4.4 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ37800.1 - 2e-16 59.8 5.2 0.002 18.3 0.0 5.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ37800.1 - 3e-14 52.6 9.6 0.0053 16.7 0.1 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 CDJ37800.1 - 3.5e-14 52.1 10.0 3e-05 23.5 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CDJ37800.1 - 3.4e-13 49.4 7.4 0.00027 21.1 0.0 4.4 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CDJ37800.1 - 6.5e-13 48.1 9.6 0.022 14.7 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Yuri_gagarin PF15934.5 CDJ37800.1 - 0.0026 17.6 2.4 0.0045 16.9 2.4 1.3 1 0 0 1 1 1 1 Yuri gagarin DUF4678 PF15727.5 CDJ37800.1 - 0.02 14.2 0.1 0.02 14.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4678) DUF241 PF03087.14 CDJ37800.1 - 0.062 13.1 0.0 0.062 13.1 0.0 1.6 2 0 0 2 2 2 0 Arabidopsis protein of unknown function DHR10 PF18595.1 CDJ37800.1 - 0.47 10.5 9.5 1.3 9.0 2.5 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain MRP-L28 PF09812.9 CDJ37800.1 - 6.8 6.8 8.6 1.1 9.3 3.4 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 TFIIS_C PF01096.18 CDJ37801.1 - 9.1e-15 54.2 9.8 1.1e-14 53.9 3.5 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 CDJ37801.1 - 0.07 13.3 15.9 0.9 9.7 0.0 4.4 3 1 0 3 3 3 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.13 CDJ37801.1 - 0.085 12.6 0.6 0.085 12.6 0.6 4.3 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit DUF2757 PF10955.8 CDJ37801.1 - 0.34 11.2 9.7 4.3 7.7 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) DUF2688 PF10892.8 CDJ37801.1 - 0.45 10.0 3.5 3.8 7.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) zinc_ribbon_4 PF13717.6 CDJ37801.1 - 0.85 9.6 9.2 2.3 8.2 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Nudix_N_2 PF14803.6 CDJ37801.1 - 4.3 7.3 13.3 6.5 6.8 0.1 4.2 4 0 0 4 4 4 0 Nudix N-terminal C1_4 PF07975.12 CDJ37801.1 - 6.4 7.1 8.9 3.7 7.9 1.4 2.9 2 1 0 2 2 2 0 TFIIH C1-like domain Exo_endo_phos PF03372.23 CDJ37802.1 - 9.7e-18 64.5 0.2 1.4e-17 64.0 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ABC_ATPase PF09818.9 CDJ37804.1 - 3.7e-176 586.3 0.0 5.3e-176 585.8 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 CDJ37804.1 - 0.0011 19.5 0.1 0.0021 18.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDJ37804.1 - 0.079 12.7 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNase_T PF00929.24 CDJ37805.1 - 2.6e-06 28.1 0.0 1.8e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 Exonuclease PLAC PF08686.11 CDJ37805.1 - 0.2 12.5 1.1 0.99 10.2 0.7 2.4 2 0 0 2 2 2 0 PLAC (protease and lacunin) domain Myosin_head PF00063.21 CDJ37806.1 - 4.9e-172 573.6 0.0 6.4e-172 573.3 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Dynein_light PF01221.18 CDJ37806.1 - 1.5e-05 25.2 0.0 0.0018 18.6 0.0 3.0 2 0 0 2 2 2 1 Dynein light chain type 1 AAA_16 PF13191.6 CDJ37806.1 - 0.077 13.4 0.9 0.24 11.8 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain U1snRNP70_N PF12220.8 CDJ37806.1 - 4.1 8.1 6.8 0.61 10.8 2.5 1.8 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AAA PF00004.29 CDJ37807.1 - 1.1e-83 278.3 0.0 2.4e-40 138.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ37807.1 - 5.9e-14 52.1 0.0 1.6e-05 24.7 0.0 2.8 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 CDJ37807.1 - 3.6e-12 45.9 1.6 0.00013 21.7 0.1 3.2 3 0 0 3 3 2 2 AAA+ lid domain IstB_IS21 PF01695.17 CDJ37807.1 - 2.1e-10 40.6 0.0 0.00012 21.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 CDJ37807.1 - 2.8e-09 37.4 0.1 0.0082 16.4 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CDJ37807.1 - 4.3e-09 37.0 3.6 0.038 14.4 0.0 5.2 3 2 1 5 5 5 2 AAA ATPase domain TIP49 PF06068.13 CDJ37807.1 - 3.4e-08 33.1 0.0 0.0074 15.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 CDJ37807.1 - 2.7e-07 30.7 0.1 0.06 13.3 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CDJ37807.1 - 4.7e-07 29.9 0.0 0.048 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CDJ37807.1 - 5.2e-07 30.3 0.0 0.068 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 CDJ37807.1 - 8.4e-07 29.4 0.0 0.079 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 CDJ37807.1 - 9.2e-07 29.1 0.0 0.073 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TsaE PF02367.17 CDJ37807.1 - 1.2e-06 28.5 0.0 0.034 14.1 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CDJ37807.1 - 1.3e-06 27.9 0.3 0.061 12.7 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDJ37807.1 - 2.4e-06 27.9 0.0 0.13 12.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 CDJ37807.1 - 3.5e-06 27.2 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CDJ37807.1 - 4.6e-06 26.4 0.0 0.18 11.5 0.0 3.9 2 2 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 CDJ37807.1 - 8.3e-06 25.7 0.0 0.21 11.5 0.0 2.8 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 CDJ37807.1 - 2.7e-05 23.4 0.0 0.22 10.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.16 CDJ37807.1 - 4.2e-05 23.1 0.1 0.32 10.4 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.27 CDJ37807.1 - 4.7e-05 23.9 0.0 0.68 10.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_7 PF12775.7 CDJ37807.1 - 4.7e-05 23.0 0.0 0.32 10.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF2075 PF09848.9 CDJ37807.1 - 0.0001 21.7 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 CDJ37807.1 - 0.00011 22.4 0.0 0.29 11.3 0.0 2.9 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 CDJ37807.1 - 0.00011 21.8 2.8 0.49 9.9 0.2 3.7 2 2 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CDJ37807.1 - 0.00026 20.8 0.0 0.93 9.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CDJ37807.1 - 0.00059 19.8 0.1 1.8 8.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.6 CDJ37807.1 - 0.00075 19.9 0.0 2.2 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 CDJ37807.1 - 0.0014 18.6 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_19 PF13245.6 CDJ37807.1 - 0.0018 18.6 0.0 3.6 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CDJ37807.1 - 0.0028 17.4 0.0 4.2 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CDJ37807.1 - 0.0028 17.5 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain SAM_Ste50p PF09235.10 CDJ37807.1 - 0.0056 16.9 0.4 3.4 8.0 0.1 2.5 2 0 0 2 2 2 1 Ste50p, sterile alpha motif NTPase_1 PF03266.15 CDJ37807.1 - 0.0059 16.5 0.1 5.6 6.8 0.0 2.6 2 0 0 2 2 2 0 NTPase ATPase PF06745.13 CDJ37807.1 - 0.0074 15.7 0.0 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 CDJ37807.1 - 0.016 14.3 0.0 1.9 7.5 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_6 PF12774.7 CDJ37807.1 - 0.026 13.5 0.1 6.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region DUF815 PF05673.13 CDJ37807.1 - 0.032 13.4 0.0 4.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 CDJ37807.1 - 0.052 13.3 0.1 16 5.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Bac_DnaA PF00308.18 CDJ37807.1 - 0.07 13.0 0.0 18 5.1 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein NB-ARC PF00931.22 CDJ37807.1 - 0.11 11.7 0.0 15 4.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 CDJ37807.1 - 0.11 11.8 0.0 18 4.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SKI PF01202.22 CDJ37807.1 - 0.11 12.6 0.0 24 5.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin PF02224.18 CDJ37807.1 - 0.12 12.1 0.0 21 4.8 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase RIO1 PF01163.22 CDJ37808.1 - 1.5e-46 158.4 0.2 2.5e-46 157.7 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CDJ37808.1 - 3.1e-32 110.6 0.7 9.6e-32 109.1 0.7 1.9 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 CDJ37808.1 - 4.3e-08 33.4 4.4 0.0014 18.6 1.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CDJ37808.1 - 5.2e-07 29.2 0.8 4.6e-06 26.1 0.8 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CDJ37808.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 CDJ37808.1 - 0.54 9.0 4.5 0.72 8.6 0.1 2.1 2 0 0 2 2 2 0 Fungal protein kinase Raftlin PF15250.6 CDJ37808.1 - 2.2 7.0 9.2 3 6.5 9.2 1.1 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 CDJ37808.1 - 5.6 5.1 15.4 3.8 5.7 13.5 1.6 2 0 0 2 2 2 0 CDC45-like protein Hid1 PF12722.7 CDJ37808.1 - 8.4 4.4 8.9 12 3.8 8.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BUD22 PF09073.10 CDJ37808.1 - 8.5 5.6 19.5 13 5.0 19.5 1.2 1 0 0 1 1 1 0 BUD22 STI1 PF17830.1 CDJ37809.1 - 0.0044 16.9 1.6 0.014 15.3 1.6 1.8 1 1 0 1 1 1 1 STI1 domain GerD PF17898.1 CDJ37809.1 - 0.011 15.7 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 Spore germination GerD central core domain Glutaredoxin PF00462.24 CDJ37810.1 - 1.6e-16 60.3 0.0 2.3e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CDJ37810.1 - 0.00019 21.4 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 CDJ37810.1 - 0.0034 17.2 0.0 0.0044 16.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.14 CDJ37810.1 - 0.0041 17.5 0.0 0.0062 16.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 CDJ37810.1 - 0.034 14.6 0.2 0.064 13.7 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain GST_N_3 PF13417.6 CDJ37810.1 - 0.039 14.4 0.0 0.058 13.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ogr_Delta PF04606.12 CDJ37810.1 - 0.052 13.5 0.1 0.052 13.5 0.1 2.4 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger TraF PF13728.6 CDJ37810.1 - 0.073 12.9 0.0 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 CDJ37810.1 - 0.19 11.9 0.5 15 5.7 0.3 2.2 1 1 1 2 2 2 0 Thioredoxin DEAD PF00270.29 CDJ37811.1 - 8.3e-38 129.9 1.5 3.6e-37 127.8 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ37811.1 - 7.1e-17 61.8 5.7 5.9e-11 42.7 0.1 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DUF4217 PF13959.6 CDJ37811.1 - 9.7e-10 38.5 0.0 2.4e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CDJ37811.1 - 5.8e-05 23.2 0.0 5.8e-05 23.2 0.0 3.4 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit IMS PF00817.20 CDJ37812.1 - 6e-31 107.5 0.3 1.6e-30 106.1 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family BRCT_2 PF16589.5 CDJ37812.1 - 2.5e-05 24.6 0.0 0.0016 18.8 0.0 3.1 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 CDJ37812.1 - 0.0019 18.9 0.0 0.0084 16.8 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain Duffy_binding PF05424.11 CDJ37812.1 - 0.046 13.8 0.4 2.8 8.0 0.0 2.7 2 0 0 2 2 2 0 Duffy binding domain ATP-synt_10 PF05176.14 CDJ37813.1 - 0.042 13.1 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP10 protein DUF493 PF04359.14 CDJ37814.1 - 1.4e-08 35.2 0.0 61 4.3 0.0 7.2 7 0 0 7 7 7 3 Protein of unknown function (DUF493) PRP3 PF08572.10 CDJ37814.1 - 0.00039 20.2 43.9 1.3 8.7 0.6 7.7 7 1 0 7 7 7 7 pre-mRNA processing factor 3 (PRP3) Spc7_N PF15402.6 CDJ37815.1 - 0.02 13.2 10.5 0.028 12.7 10.5 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 TFIIA PF03153.13 CDJ37815.1 - 0.29 11.1 22.0 0.47 10.4 22.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ37815.1 - 0.57 10.0 5.3 0.9 9.3 5.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.6 CDJ37815.1 - 1.7 7.3 7.3 2.3 6.8 7.3 1.1 1 0 0 1 1 1 0 Raftlin FGF-BP1 PF06473.12 CDJ37815.1 - 3.7 7.3 15.9 1.8 8.4 13.7 1.5 1 1 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Nup54 PF13874.6 CDJ37816.1 - 3.1e-13 50.0 1.2 3.1e-13 50.0 1.2 3.6 2 1 1 3 3 3 1 Nucleoporin complex subunit 54 VGPC1_C PF16799.5 CDJ37816.1 - 0.5 10.4 7.9 0.18 11.8 1.1 3.1 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Cluap1 PF10234.9 CDJ37816.1 - 0.57 9.5 8.2 0.039 13.3 2.0 2.0 2 1 0 2 2 2 0 Clusterin-associated protein-1 WES_acyltransf PF03007.16 CDJ37816.1 - 4.5 7.0 15.8 0.053 13.3 2.4 2.9 2 1 1 3 3 3 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Histone_H2A_C PF16211.5 CDJ37818.1 - 7e-19 67.3 0.3 7e-19 67.3 0.3 1.7 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 CDJ37818.1 - 3.4e-15 56.6 0.0 7.1e-15 55.5 0.0 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDJ37818.1 - 0.0001 22.5 0.0 0.00015 22.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ37819.1 - 1.2e-54 184.2 1.4 1.3e-54 184.0 1.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 CDJ37819.1 - 0.00024 21.7 0.9 0.00029 21.4 0.9 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CDJ37819.1 - 0.00039 20.5 0.1 0.00072 19.6 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CDJ37819.1 - 0.00046 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CDJ37819.1 - 0.0065 16.7 0.5 0.01 16.1 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CDJ37819.1 - 0.016 15.3 0.1 0.027 14.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit RRM_1 PF00076.22 CDJ37820.1 - 5.4e-12 45.4 0.1 3.1e-11 42.9 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3918 PF13056.6 CDJ37822.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Hid1 PF12722.7 CDJ37823.1 - 9.8e-08 30.6 10.0 2.5e-07 29.2 6.3 4.1 2 1 2 4 4 3 2 High-temperature-induced dauer-formation protein SR-25 PF10500.9 CDJ37823.1 - 0.00018 21.2 7.3 0.00018 21.2 7.3 3.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ37823.1 - 0.00021 21.6 2.6 0.00021 21.6 2.6 6.5 3 3 1 5 5 3 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ37823.1 - 0.00054 19.7 13.4 0.00054 19.7 13.4 3.9 4 1 0 4 4 3 2 Spt20 family SDA1 PF05285.12 CDJ37823.1 - 0.0014 18.1 14.1 0.0016 17.9 3.7 2.4 2 0 0 2 2 2 2 SDA1 IMUP PF15761.5 CDJ37823.1 - 0.014 16.1 4.6 0.014 16.1 4.6 2.9 3 1 0 3 3 3 0 Immortalisation up-regulated protein Cwf_Cwc_15 PF04889.12 CDJ37823.1 - 0.06 13.1 0.3 0.06 13.1 0.3 3.3 3 1 0 3 3 2 0 Cwf15/Cwc15 cell cycle control protein DUF3381 PF11861.8 CDJ37823.1 - 0.18 11.6 0.1 0.18 11.6 0.1 3.5 3 1 0 3 3 2 0 Domain of unknown function (DUF3381) GPCR_chapero_1 PF11904.8 CDJ37823.1 - 1.4 8.3 11.3 0.9 8.9 3.8 2.5 2 0 0 2 2 2 0 GPCR-chaperone Peptidase_S64 PF08192.11 CDJ37823.1 - 2.8 6.3 25.5 2.5 6.5 13.4 2.2 2 0 0 2 2 2 0 Peptidase family S64 DUF913 PF06025.12 CDJ37823.1 - 4.7 6.1 22.7 2 7.3 1.3 2.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF913) Plasmodium_Vir PF05795.11 CDJ37823.1 - 5.4 6.3 15.9 1.2 8.4 5.4 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein AAA_18 PF13238.6 CDJ37824.1 - 5.7e-23 81.9 0.0 7.5e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CDJ37824.1 - 9.4e-08 32.6 0.0 3.8e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ37824.1 - 1.9e-05 25.1 0.0 4.4e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CDJ37824.1 - 3.7e-05 23.9 0.0 0.00061 20.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain ADK PF00406.22 CDJ37824.1 - 0.00046 20.3 0.0 0.0044 17.1 0.0 2.1 1 1 1 2 2 2 1 Adenylate kinase AAA_28 PF13521.6 CDJ37824.1 - 0.0013 19.0 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 CDJ37824.1 - 0.0018 18.4 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA PF00004.29 CDJ37824.1 - 0.0019 18.6 0.0 0.0033 17.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 CDJ37824.1 - 0.0023 17.7 0.0 0.0042 16.8 0.0 1.4 2 0 0 2 2 1 1 Cytidylate kinase KTI12 PF08433.10 CDJ37824.1 - 0.0066 15.9 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 RNA_helicase PF00910.22 CDJ37824.1 - 0.0078 16.6 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 CDJ37824.1 - 0.009 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_22 PF13401.6 CDJ37824.1 - 0.011 16.0 0.2 0.019 15.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CDJ37824.1 - 0.012 15.6 0.0 0.044 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CDJ37824.1 - 0.015 14.5 0.1 0.035 13.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 CDJ37824.1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CDJ37824.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 CDJ37824.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ParA PF10609.9 CDJ37824.1 - 0.057 12.9 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase MeaB PF03308.16 CDJ37824.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 CDJ37824.1 - 0.094 12.8 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 CDJ37824.1 - 0.095 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 CDJ37824.1 - 0.099 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 CDJ37824.1 - 0.1 12.4 0.0 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain dNK PF01712.19 CDJ37824.1 - 0.12 12.2 0.1 0.41 10.5 0.0 1.9 2 1 0 2 2 2 0 Deoxynucleoside kinase Ploopntkinase3 PF18751.1 CDJ37824.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 CDJ37824.1 - 0.14 11.4 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Hydin_ADK PF17213.3 CDJ37824.1 - 0.17 12.1 0.2 0.35 11.1 0.0 1.5 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain CbiA PF01656.23 CDJ37824.1 - 0.18 11.9 0.1 0.37 10.9 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 CDJ37824.1 - 0.2 11.4 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 CDJ37824.1 - 0.21 10.7 0.0 0.43 9.7 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase Proteasome PF00227.26 CDJ37825.1 - 4.3e-34 117.7 0.1 7.6e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit RNA_pol_A_bac PF01000.26 CDJ37825.1 - 0.16 12.3 0.1 0.27 11.6 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/RpoA insert domain Dehydrin PF00257.19 CDJ37825.1 - 4.4 7.8 10.2 0.41 11.2 4.9 2.0 1 1 0 1 1 1 0 Dehydrin Methyltransf_11 PF08241.12 CDJ37826.1 - 0.059 14.0 0.0 0.3 11.7 0.0 2.3 1 0 0 1 1 1 0 Methyltransferase domain FAM199X PF15814.5 CDJ37827.1 - 0.06 12.4 39.7 0.01 14.9 16.4 2.1 2 0 0 2 2 2 0 Protein family FAM199X SprA-related PF12118.8 CDJ37827.1 - 3.9 6.5 56.3 0.41 9.7 26.2 2.1 2 0 0 2 2 2 0 SprA-related family MMR_HSR1_Xtn PF16897.5 CDJ37829.1 - 1.1e-40 137.9 0.1 1.9e-40 137.1 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CDJ37829.1 - 2.9e-23 81.7 0.0 6.9e-23 80.5 0.0 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CDJ37829.1 - 2.6e-21 75.8 0.0 4.8e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ37829.1 - 9e-12 44.8 0.1 6.5e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ37829.1 - 0.00013 22.0 0.2 0.43 10.6 0.2 2.4 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 CDJ37829.1 - 0.00059 18.9 0.3 0.0026 16.8 0.1 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 CDJ37829.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.27 CDJ37829.1 - 0.11 12.0 0.2 5.8 6.4 0.0 2.8 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ37829.1 - 0.29 11.0 1.1 0.7 9.8 0.1 2.1 2 1 1 3 3 3 0 RsgA GTPase PH PF00169.29 CDJ37830.1 - 0.0039 17.7 0.1 0.02 15.4 0.1 2.0 1 1 0 1 1 1 1 PH domain Pkinase PF00069.25 CDJ37831.1 - 3.2e-06 26.7 0.0 0.0018 17.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain zf-CCCH PF00642.24 CDJ37831.1 - 5.5e-06 26.2 16.6 0.00078 19.3 2.3 3.4 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ37831.1 - 0.003 17.6 2.5 0.003 17.6 2.5 3.9 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ37831.1 - 0.0053 16.5 8.6 0.0054 16.5 1.1 2.6 2 0 0 2 2 2 1 CCCH-type zinc finger Pkinase_Tyr PF07714.17 CDJ37831.1 - 0.12 11.6 0.0 1.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein tyrosine kinase PBP_like PF12727.7 CDJ37832.1 - 6.1 5.9 9.4 0.62 9.2 1.1 2.3 2 0 0 2 2 2 0 PBP superfamily domain bZIP_2 PF07716.15 CDJ37833.1 - 0.053 13.6 3.0 0.053 13.6 3.0 2.4 2 0 0 2 2 2 0 Basic region leucine zipper UPF0242 PF06785.11 CDJ37833.1 - 0.063 13.4 12.7 0.13 12.4 12.8 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HemX PF04375.14 CDJ37833.1 - 0.45 9.7 5.7 0.48 9.7 5.7 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3552 PF12072.8 CDJ37833.1 - 0.93 8.9 18.3 0.45 9.9 15.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) APG6_N PF17675.1 CDJ37833.1 - 1.9 9.0 13.6 2.4 8.7 13.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region OmpH PF03938.14 CDJ37833.1 - 9.5 6.6 11.8 11 6.4 11.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF5384 PF17358.2 CDJ37834.1 - 0.0091 16.0 8.8 0.0091 16.0 8.8 2.6 2 0 0 2 2 2 1 Family of unknown function (DUF5384) Phage_holin_2_4 PF16082.5 CDJ37834.1 - 0.056 13.2 0.5 0.056 13.2 0.5 2.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like baeRF_family7 PF18849.1 CDJ37834.1 - 0.21 11.8 4.1 0.092 12.9 0.9 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 TssO PF17561.2 CDJ37834.1 - 0.36 10.9 0.1 0.36 10.9 0.1 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssO Halogen_Hydrol PF10112.9 CDJ37834.1 - 3.9 7.4 9.7 0.14 12.2 2.3 2.3 1 1 2 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein EMC3_TMCO1 PF01956.16 CDJ37834.1 - 4.2 7.1 10.0 0.063 13.0 1.5 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Ribosomal_L37 PF08561.10 CDJ37834.1 - 8 7.0 16.7 2 8.9 2.5 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 mRNA_cap_enzyme PF01331.19 CDJ37835.1 - 1.5e-41 142.4 0.0 5.1e-39 134.1 0.0 3.2 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CDJ37835.1 - 1.9e-10 41.3 0.0 5.5e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 CDJ37835.1 - 0.00014 21.6 0.3 0.012 15.2 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain DUF5346 PF17281.2 CDJ37835.1 - 0.032 14.2 0.0 0.085 12.9 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5346) SUIM_assoc PF16619.5 CDJ37835.1 - 0.33 11.0 6.9 9.9 6.3 0.1 3.3 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Sensor_TM1 PF13755.6 CDJ37836.1 - 0.049 13.4 0.9 0.16 11.7 0.9 1.9 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain SARAF PF06682.12 CDJ37836.1 - 9.1 5.8 10.2 32 4.0 4.8 2.8 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis MIF4G PF02854.19 CDJ37837.1 - 2.9e-28 99.0 0.4 3.7e-28 98.6 0.4 1.1 1 0 0 1 1 1 1 MIF4G domain Transket_pyr PF02779.24 CDJ37838.1 - 7.9e-42 142.9 0.0 1.4e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDJ37838.1 - 9.9e-37 125.6 0.1 1.6e-36 124.9 0.1 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain ETF PF01012.21 CDJ37838.1 - 0.27 11.1 3.1 0.44 10.4 3.1 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein domain DUF4805 PF16063.5 CDJ37840.1 - 0.2 11.0 1.5 0.31 10.3 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) SUIM_assoc PF16619.5 CDJ37841.1 - 0.0095 16.0 3.8 0.035 14.2 3.8 2.0 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 RsbU_N PF08673.10 CDJ37843.1 - 7.2 6.8 6.5 9.1 6.5 0.4 2.5 3 0 0 3 3 3 0 Phosphoserine phosphatase RsbU, N-terminal domain Synaptonemal_3 PF15191.6 CDJ37844.1 - 0.013 15.2 0.1 0.033 14.0 0.0 1.6 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 Apolipoprotein PF01442.18 CDJ37844.1 - 0.016 15.1 0.1 0.31 10.9 0.1 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Ndc80_HEC PF03801.13 CDJ37845.1 - 2.2e-25 89.1 0.0 2.2e-25 89.1 0.0 3.0 3 0 0 3 3 3 1 HEC/Ndc80p family GAS PF13851.6 CDJ37845.1 - 0.00051 19.5 7.2 0.00051 19.5 7.2 4.0 2 2 1 3 3 3 2 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 CDJ37845.1 - 0.00061 19.9 23.3 0.00061 19.9 23.3 4.9 3 1 2 5 5 5 2 TPR/MLP1/MLP2-like protein Mcm10 PF09332.11 CDJ37846.1 - 0.0002 20.9 18.8 0.0002 20.9 18.8 3.1 2 1 1 3 3 3 1 Mcm10 replication factor DUF5421 PF17458.2 CDJ37846.1 - 0.014 14.8 3.0 0.014 14.8 3.0 3.4 3 1 0 3 3 3 0 Family of unknown function (DUF5421) Porph_ging PF09697.10 CDJ37846.1 - 0.52 10.9 0.1 0.52 10.9 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (Porph_ging) Peptidase_S15 PF02129.18 CDJ37847.1 - 0.019 14.6 21.5 0.61 9.6 0.4 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) eIF3_subunit PF08597.10 CDJ37847.1 - 0.069 13.1 24.0 0.014 15.3 19.8 1.8 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit GREB1 PF15782.5 CDJ37847.1 - 0.17 9.0 22.3 0.2 8.8 22.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4045 PF13254.6 CDJ37847.1 - 0.35 10.5 24.4 0.03 14.0 19.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) CCSAP PF15748.5 CDJ37847.1 - 0.51 10.5 31.0 0.076 13.2 25.7 1.9 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF2052 PF09747.9 CDJ37847.1 - 0.91 9.6 29.1 0.88 9.7 25.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CDJ37847.1 - 1.7 8.4 32.4 0.23 11.2 28.0 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CDJ37847.1 - 1.8 7.5 13.2 0.5 9.3 10.3 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF2828 PF11443.8 CDJ37847.1 - 1.8 6.5 22.3 0.31 9.1 18.9 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) CRT10 PF08728.10 CDJ37847.1 - 2 6.5 9.6 2.1 6.4 9.6 1.1 1 0 0 1 1 1 0 CRT10 PTPRCAP PF15713.5 CDJ37847.1 - 4.2 7.7 34.9 3.3 8.0 29.9 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated HCO3_cotransp PF00955.21 CDJ37847.1 - 6.1 5.5 7.3 9.6 4.9 7.3 1.4 1 0 0 1 1 1 0 HCO3- transporter family ALMT PF11744.8 CDJ37847.1 - 9.2 5.0 23.1 0.93 8.2 18.9 1.4 2 0 0 2 2 2 0 Aluminium activated malate transporter eIF-3_zeta PF05091.12 CDJ37847.1 - 9.3 5.1 33.1 2.9 6.8 27.2 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Membralin PF09746.9 CDJ37847.1 - 9.5 5.1 13.7 15 4.5 13.7 1.4 1 0 0 1 1 1 0 Tumour-associated protein ECR1_N PF14382.6 CDJ37848.1 - 9.6e-07 28.5 0.1 1.6e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 CDJ37848.1 - 0.00034 20.9 0.1 0.00075 19.8 0.1 1.6 1 0 0 1 1 1 1 KH domain B12D PF06522.11 CDJ37851.1 - 0.003 17.3 0.0 0.0058 16.4 0.0 1.5 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit cNMP_binding PF00027.29 CDJ37852.1 - 3.9e-40 135.8 0.1 2.6e-20 72.3 0.1 2.8 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Serglycin PF04360.12 CDJ37852.1 - 0.018 15.0 7.1 0.039 13.9 7.1 1.5 1 0 0 1 1 1 0 Serglycin Spt20 PF12090.8 CDJ37853.1 - 0.31 10.6 9.7 0.32 10.6 9.7 1.1 1 0 0 1 1 1 0 Spt20 family CDK2AP PF09806.9 CDJ37854.1 - 0.27 11.3 2.8 0.33 11.0 2.8 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SelK_SelG PF10961.8 CDJ37854.1 - 0.31 11.7 12.6 0.53 10.9 12.6 1.4 1 0 0 1 1 1 0 Selenoprotein SelK_SelG RAP PF08373.10 CDJ37855.1 - 0.0022 18.0 0.4 0.0049 16.9 0.0 1.7 2 0 0 2 2 2 1 RAP domain DDHD PF02862.17 CDJ37855.1 - 0.0077 16.4 4.5 0.0077 16.4 4.5 1.7 2 0 0 2 2 2 1 DDHD domain Peptidase_S49_N PF08496.10 CDJ37855.1 - 0.032 14.3 9.3 0.068 13.2 9.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CLN3 PF02487.17 CDJ37855.1 - 0.21 10.6 6.3 0.36 9.8 6.3 1.4 1 0 0 1 1 1 0 CLN3 protein SLC12 PF03522.15 CDJ37855.1 - 0.23 10.4 10.9 0.33 9.9 10.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Exonuc_VII_L PF02601.15 CDJ37855.1 - 0.3 10.6 13.5 0.46 10.0 13.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Presenilin PF01080.17 CDJ37855.1 - 0.41 9.4 16.0 0.66 8.7 16.0 1.2 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 CDJ37855.1 - 0.44 8.9 0.7 0.56 8.5 0.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 CDJ37855.1 - 0.71 9.6 11.5 1.2 8.9 11.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Isy1 PF06246.12 CDJ37855.1 - 0.74 9.3 15.1 1.2 8.7 15.1 1.3 1 0 0 1 1 1 0 Isy1-like splicing family Neur_chan_memb PF02932.16 CDJ37855.1 - 1.1 9.3 10.7 2.3 8.2 10.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CSG2 PF16965.5 CDJ37855.1 - 3 6.7 5.6 5.4 5.9 5.6 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Zip PF02535.22 CDJ37855.1 - 3.4 6.8 6.6 6.5 5.9 6.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Het-C PF07217.11 CDJ37855.1 - 5.4 5.4 9.3 7.4 5.0 9.3 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Serinc PF03348.15 CDJ37855.1 - 5.5 5.8 6.2 9.5 5.0 6.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) LpxB PF02684.15 CDJ37855.1 - 8.9 5.0 10.8 14 4.4 10.8 1.2 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase DUF4407 PF14362.6 CDJ37855.1 - 9.3 5.5 16.2 25 4.1 16.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3552 PF12072.8 CDJ37856.1 - 0.0024 17.3 39.8 0.0024 17.3 39.8 10.9 4 1 8 12 12 12 3 Domain of unknown function (DUF3552) DNA_ligase_A_M PF01068.21 CDJ37858.1 - 1.1e-21 77.5 0.0 3e-21 76.0 0.0 1.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 CDJ37858.1 - 1.2e-07 32.2 0.0 3.4e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_N PF04675.14 CDJ37858.1 - 0.00074 19.9 5.2 0.029 14.7 0.0 3.4 3 1 1 4 4 4 2 DNA ligase N terminus Neur_chan_memb PF02932.16 CDJ37858.1 - 0.17 11.9 10.2 1.6 8.8 3.1 2.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SRP9-21 PF05486.12 CDJ37858.1 - 3.5 8.1 7.8 0.95 9.9 0.1 3.5 3 0 0 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) RR_TM4-6 PF06459.12 CDJ37858.1 - 4.6 7.0 12.0 5 6.9 0.5 2.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.10 CDJ37859.1 - 2.1 6.9 4.9 2.3 6.8 4.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LEA_4 PF02987.16 CDJ37860.1 - 0.0011 19.0 38.8 0.0056 16.7 5.6 3.7 4 0 0 4 4 4 3 Late embryogenesis abundant protein YtxH PF12732.7 CDJ37860.1 - 0.0011 19.5 18.6 0.0042 17.6 3.3 2.5 1 1 1 2 2 2 2 YtxH-like protein Apolipoprotein PF01442.18 CDJ37860.1 - 0.045 13.6 7.3 0.06 13.2 7.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HSP9_HSP12 PF04119.12 CDJ37860.1 - 0.74 10.3 11.6 2.4 8.6 3.8 3.5 2 2 0 2 2 2 0 Heat shock protein 9/12 DUF883 PF05957.13 CDJ37860.1 - 0.88 10.2 19.7 3.6 8.3 1.3 2.9 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) Med3 PF11593.8 CDJ37861.1 - 0.0019 17.5 9.8 0.0019 17.5 9.8 11.0 7 5 1 9 9 9 1 Mediator complex subunit 3 fungal DUF247 PF03140.15 CDJ37861.1 - 2.8 7.1 5.3 5.5 6.1 1.0 2.8 3 0 0 3 3 3 0 Plant protein of unknown function Spt20 PF12090.8 CDJ37862.1 - 0.00094 18.9 11.0 0.00094 18.9 11.0 2.5 3 0 0 3 3 3 2 Spt20 family DUF2722 PF10846.8 CDJ37862.1 - 0.01 14.8 9.2 0.01 14.8 9.2 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ37862.1 - 0.013 15.8 17.1 0.013 15.8 17.1 5.1 2 2 2 4 4 4 0 Anti-sigma-K factor rskA Activator_LAG-3 PF11498.8 CDJ37862.1 - 0.14 11.1 24.7 0.05 12.6 13.4 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 TFIIIC_sub6 PF10419.9 CDJ37862.1 - 0.29 11.0 6.0 0.082 12.8 3.1 1.7 2 1 0 2 2 2 0 TFIIIC subunit triple barrel domain Tau95_N PF17682.1 CDJ37862.1 - 0.4 10.9 5.9 0.068 13.4 1.3 1.9 2 0 0 2 2 2 0 Tau95 Triple barrel domain DUF4834 PF16118.5 CDJ37862.1 - 1.4 10.0 13.3 0.23 12.4 4.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) MAP65_ASE1 PF03999.12 CDJ37862.1 - 2.5 6.7 12.8 0.35 9.5 7.9 1.8 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) TFIIA PF03153.13 CDJ37862.1 - 3.2 7.7 44.4 93 2.8 44.4 2.0 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3381 PF11861.8 CDJ37862.1 - 5.9 6.7 12.7 2.4 7.9 7.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Wzy_C PF04932.15 CDJ37864.1 - 0.0079 15.8 0.7 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 O-Antigen ligase DUF3531 PF12049.8 CDJ37864.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3531) SelK_SelG PF10961.8 CDJ37864.1 - 1.1 9.9 3.6 1.8 9.3 0.0 2.8 3 0 0 3 3 3 0 Selenoprotein SelK_SelG ABC_tran PF00005.27 CDJ37865.1 - 8.6e-49 165.6 0.0 1.4e-26 93.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CDJ37865.1 - 1.8e-33 116.1 35.7 3.8e-29 101.9 3.1 2.5 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ37865.1 - 1e-15 58.4 0.8 1.1e-05 25.4 0.0 4.5 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ37865.1 - 1.4e-05 24.7 1.0 0.086 12.6 0.2 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ37865.1 - 0.00012 22.0 0.5 0.026 14.4 0.1 3.2 3 0 0 3 3 3 1 RsgA GTPase AAA_23 PF13476.6 CDJ37865.1 - 0.0013 19.3 3.7 0.025 15.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 CDJ37865.1 - 0.0096 15.4 0.1 14 5.1 0.0 3.5 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CDJ37865.1 - 0.036 13.3 0.3 0.32 10.2 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin DUF4162 PF13732.6 CDJ37865.1 - 0.043 14.5 0.0 2.4 8.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_30 PF13604.6 CDJ37865.1 - 0.045 13.5 0.2 14 5.4 0.2 2.6 2 0 0 2 2 2 0 AAA domain DUF4658 PF15555.6 CDJ37865.1 - 0.053 13.6 1.2 9 6.4 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4658) AAA_16 PF13191.6 CDJ37865.1 - 0.062 13.7 0.1 12 6.3 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 CDJ37865.1 - 0.12 11.3 1.2 1.9 7.4 0.3 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 CDJ37865.1 - 0.14 12.3 4.2 0.43 10.7 0.6 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 CDJ37865.1 - 0.21 11.6 3.8 3 7.9 0.4 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain SRP54 PF00448.22 CDJ37865.1 - 0.28 10.8 2.2 0.82 9.3 0.0 2.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 CDJ37865.1 - 2.2 8.2 3.8 2.8 7.8 0.1 2.7 3 0 0 3 3 3 0 NTPase IMP2_N PF18590.1 CDJ37867.1 - 2.1e-24 85.9 1.3 2.1e-24 85.9 1.3 1.6 2 0 0 2 2 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain TFIIA PF03153.13 CDJ37867.1 - 0.031 14.3 30.0 0.047 13.7 30.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ37867.1 - 0.5 10.3 12.3 0.69 9.8 12.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GREB1 PF15782.5 CDJ37867.1 - 1.4 6.0 13.5 1.5 5.8 13.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SMYLE_N PF18615.1 CDJ37867.1 - 1.6 8.2 9.0 2 7.9 9.0 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Presenilin PF01080.17 CDJ37867.1 - 2 7.1 16.3 2.5 6.8 16.3 1.2 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 CDJ37867.1 - 2.5 7.6 12.9 3.8 7.0 12.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist eIF-3_zeta PF05091.12 CDJ37867.1 - 4.8 6.0 13.3 6.8 5.5 13.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Connexin PF00029.19 CDJ37867.1 - 7.1 6.3 5.0 10 5.8 5.0 1.3 1 0 0 1 1 1 0 Connexin FAM163 PF15069.6 CDJ37867.1 - 7.4 7.0 6.9 0.9 10.0 2.6 1.6 2 0 0 2 2 2 0 FAM163 family DUF5521 PF17659.1 CDJ37867.1 - 7.8 4.2 9.7 9.4 3.9 9.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Hamartin PF04388.12 CDJ37867.1 - 9.2 4.8 11.8 11 4.5 11.8 1.1 1 0 0 1 1 1 0 Hamartin protein CLP_protease PF00574.23 CDJ37868.1 - 1.9e-28 99.6 0.0 4.2e-25 88.7 0.0 2.1 1 1 1 2 2 2 2 Clp protease Metalloenzyme PF01676.18 CDJ37868.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF1289 PF06945.13 CDJ37868.1 - 0.025 14.4 0.2 0.092 12.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Glyco_tranf_2_3 PF13641.6 CDJ37868.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Slu7 PF11708.8 CDJ37869.1 - 2.3e-74 250.5 18.9 2.3e-74 250.5 18.9 3.1 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor Rrn6 PF10214.9 CDJ37869.1 - 0.12 10.8 19.0 0.16 10.4 19.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Draxin PF15550.6 CDJ37869.1 - 0.68 9.7 11.4 24 4.7 13.2 2.3 2 0 0 2 2 2 0 Draxin DUF3381 PF11861.8 CDJ37869.1 - 0.82 9.5 12.3 3 7.6 12.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF3458_C PF17432.2 CDJ37870.1 - 1.6e-18 67.2 0.1 1.6e-18 67.2 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3458_C) ARM repeats EI24 PF07264.11 CDJ37870.1 - 3.1e-05 24.3 11.1 7.6e-05 23.0 11.1 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SUIM_assoc PF16619.5 CDJ37870.1 - 0.27 11.3 7.7 1.6 8.9 3.5 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SMC_N PF02463.19 CDJ37871.1 - 1.7e-09 37.4 0.3 2.6e-09 36.8 0.3 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CDJ37871.1 - 0.00031 20.9 3.0 0.00054 20.1 0.0 2.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 CDJ37871.1 - 0.033 14.7 0.3 0.05 14.1 0.3 1.3 1 0 0 1 1 1 0 ABC transporter AAA_lid_2 PF17863.1 CDJ37871.1 - 0.11 12.4 0.2 0.11 12.4 0.2 1.9 2 0 0 2 2 2 0 AAA lid domain TFIIA PF03153.13 CDJ37873.1 - 1.2 9.0 5.0 3.5 7.5 5.0 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SRP40_C PF05022.12 CDJ37874.1 - 6.1e-24 84.7 1.0 6.1e-24 84.7 1.0 2.3 2 1 0 2 2 2 1 SRP40, C-terminal domain Hid1 PF12722.7 CDJ37874.1 - 0.83 7.7 12.0 0.96 7.5 12.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 CDJ37874.1 - 3.4 6.3 13.8 3.5 6.3 13.8 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ37874.1 - 4 6.4 10.9 4.3 6.3 10.9 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 CDJ37874.1 - 5.1 6.0 7.3 8 5.3 7.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 CDJ37874.1 - 5.4 6.1 7.7 6 6.0 7.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_60s PF00428.19 CDJ37875.1 - 1.6 9.4 16.1 4.2 8.0 2.7 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein K_channel_TID PF07941.11 CDJ37875.1 - 5 7.6 12.5 0.18 12.2 2.6 3.2 2 1 1 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain NatB_MDM20 PF09797.9 CDJ37876.1 - 0.0014 17.7 0.5 0.0043 16.1 0.5 1.7 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 CDJ37876.1 - 0.033 14.7 1.8 2.5 8.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ37876.1 - 2.7 9.1 10.0 19 6.4 0.0 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat DDRGK PF09756.9 CDJ37878.1 - 5.1e-43 146.9 15.2 5.1e-43 146.9 15.2 2.7 2 1 1 3 3 3 1 DDRGK domain BAF1_ABF1 PF04684.13 CDJ37878.1 - 0.00069 18.8 8.4 0.00095 18.3 8.4 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor HemN_C PF06969.16 CDJ37878.1 - 0.0035 17.4 0.6 0.06 13.4 0.4 2.8 1 1 1 2 2 2 1 HemN C-terminal domain RskA PF10099.9 CDJ37878.1 - 0.0079 16.5 14.2 0.011 16.0 12.4 1.9 1 1 1 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ37878.1 - 0.013 15.5 8.0 0.014 15.4 8.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hemopexin PF00045.19 CDJ37878.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Hemopexin PPP4R2 PF09184.11 CDJ37878.1 - 0.16 11.5 7.6 0.18 11.3 6.2 1.7 2 0 0 2 2 2 0 PPP4R2 SARAF PF06682.12 CDJ37878.1 - 0.19 11.3 7.2 0.25 10.9 7.2 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SR-25 PF10500.9 CDJ37878.1 - 0.82 9.2 22.6 1.5 8.3 22.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YjbH PF06082.11 CDJ37878.1 - 1 8.1 9.8 1.4 7.7 9.8 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Draxin PF15550.6 CDJ37878.1 - 2 8.2 14.9 3.6 7.4 14.9 1.4 1 0 0 1 1 1 0 Draxin GREB1 PF15782.5 CDJ37878.1 - 8.1 3.4 7.8 10 3.1 7.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hist_deacetyl PF00850.19 CDJ37879.1 - 4.3e-58 197.2 0.0 9.1e-58 196.1 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylase domain Ank_2 PF12796.7 CDJ37879.1 - 4e-10 40.1 0.2 1.5e-06 28.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ37879.1 - 5.1e-09 36.2 2.3 3.4e-07 30.4 0.2 3.7 3 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ37879.1 - 2.5e-07 31.1 4.8 0.012 16.1 0.3 4.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ37879.1 - 3.1e-06 27.1 1.1 1.2 10.0 0.1 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CDJ37879.1 - 0.00063 20.1 0.5 0.00063 20.1 0.5 4.3 4 0 0 4 4 4 2 Ankyrin repeat zf-CCCH PF00642.24 CDJ37880.1 - 9.6e-08 31.8 14.4 0.00014 21.7 3.0 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ37880.1 - 0.00013 21.6 8.9 0.0071 16.1 3.1 2.7 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CDJ37880.1 - 0.0005 20.7 0.1 0.0005 20.7 0.1 4.9 4 2 0 4 4 4 2 Torus domain zf_CCCH_4 PF18345.1 CDJ37880.1 - 0.0011 18.9 18.2 0.0035 17.3 1.7 3.7 4 1 0 4 4 4 2 Zinc finger domain zf-CCCH_3 PF15663.5 CDJ37880.1 - 0.77 10.0 12.3 0.077 13.2 0.8 3.1 2 1 1 3 3 3 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDJ37880.1 - 2.1 8.9 7.2 5.6 7.6 1.7 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger SR-25 PF10500.9 CDJ37881.1 - 5e-06 26.3 19.0 5.9e-06 26.1 19.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Connexin PF00029.19 CDJ37881.1 - 0.0018 18.1 2.3 0.0023 17.7 2.3 1.1 1 0 0 1 1 1 1 Connexin YqfQ PF14181.6 CDJ37881.1 - 0.0056 16.9 5.6 0.0065 16.7 5.6 1.2 1 0 0 1 1 1 1 YqfQ-like protein GAGA_bind PF06217.12 CDJ37881.1 - 0.0089 16.3 7.7 0.0098 16.2 7.7 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family YL1 PF05764.13 CDJ37881.1 - 0.013 15.6 15.8 0.016 15.3 15.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CPSF100_C PF13299.6 CDJ37881.1 - 0.02 15.1 4.0 0.023 14.9 4.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Rrn6 PF10214.9 CDJ37881.1 - 0.021 13.4 0.5 0.021 13.4 0.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3807 PF12720.7 CDJ37881.1 - 0.022 15.1 10.0 0.025 14.9 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) MMU163 PF17119.5 CDJ37881.1 - 0.033 13.3 1.4 0.04 13.1 1.4 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis CCDC106 PF15794.5 CDJ37881.1 - 0.034 13.8 13.0 0.041 13.6 13.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RNA_pol_Rpc4 PF05132.14 CDJ37881.1 - 0.047 14.1 7.9 0.059 13.8 7.9 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Med19 PF10278.9 CDJ37881.1 - 0.062 13.2 23.3 0.085 12.8 23.3 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4604 PF15377.6 CDJ37881.1 - 0.082 13.3 21.4 0.11 12.9 21.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) EIIBC-GUT_N PF03612.14 CDJ37881.1 - 0.1 12.3 5.5 0.14 11.9 5.5 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4770 PF15994.5 CDJ37881.1 - 0.11 12.8 5.4 0.14 12.4 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) EOS1 PF12326.8 CDJ37881.1 - 0.12 12.3 0.9 0.16 11.9 0.9 1.2 1 0 0 1 1 1 0 N-glycosylation protein U79_P34 PF03064.16 CDJ37881.1 - 0.14 11.5 12.2 0.16 11.3 12.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SpoIIP PF07454.11 CDJ37881.1 - 0.19 11.2 6.6 0.22 10.9 6.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SRP-alpha_N PF04086.13 CDJ37881.1 - 0.21 11.5 14.2 0.25 11.2 14.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 CDJ37881.1 - 0.27 10.0 2.6 0.3 9.8 2.6 1.1 1 0 0 1 1 1 0 Presenilin AP3D1 PF06375.11 CDJ37881.1 - 0.33 11.2 25.0 0.59 10.4 25.0 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF3464 PF11947.8 CDJ37881.1 - 0.34 10.6 9.8 0.47 10.2 9.8 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Protocadherin PF08374.11 CDJ37881.1 - 0.4 10.6 8.3 0.56 10.1 8.3 1.3 1 0 0 1 1 1 0 Protocadherin RNA_polI_A34 PF08208.11 CDJ37881.1 - 0.44 10.6 30.0 0.56 10.3 30.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Neur_chan_memb PF02932.16 CDJ37881.1 - 0.77 9.8 2.9 0.86 9.6 2.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Coilin_N PF15862.5 CDJ37881.1 - 0.87 9.4 19.4 1.2 9.0 19.4 1.2 1 0 0 1 1 1 0 Coilin N-terminus PPL5 PF18168.1 CDJ37881.1 - 1.2 8.4 8.1 1.5 8.1 8.1 1.1 1 0 0 1 1 1 0 Prim-pol family 5 RR_TM4-6 PF06459.12 CDJ37881.1 - 1.3 8.8 12.0 1.6 8.5 12.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 CDJ37881.1 - 1.3 6.8 3.4 1.5 6.7 3.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NARP1 PF12569.8 CDJ37881.1 - 1.5 7.6 15.6 1.8 7.3 15.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2828 PF11443.8 CDJ37881.1 - 2 6.4 10.1 2.4 6.1 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Peptidase_S49_N PF08496.10 CDJ37881.1 - 2.5 8.1 18.1 3.5 7.7 18.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sec62 PF03839.16 CDJ37881.1 - 2.6 7.5 13.0 4.1 6.9 13.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 CDC45 PF02724.14 CDJ37881.1 - 3.9 5.6 10.6 4.7 5.4 10.6 1.0 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 CDJ37881.1 - 4.2 6.0 11.0 5.4 5.7 11.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Eapp_C PF10238.9 CDJ37881.1 - 5.4 7.1 10.1 7.6 6.6 10.1 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein CMS1 PF14617.6 CDJ37881.1 - 7.9 5.7 16.4 11 5.3 16.4 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit OATP PF03137.20 CDJ37881.1 - 8.6 4.5 5.0 11 4.2 5.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ubiquitin PF00240.23 CDJ37883.1 - 2.3e-101 331.6 0.0 5e-09 35.8 0.0 11.0 1 1 10 11 11 11 11 Ubiquitin family Ubiquitin_2 PF14560.6 CDJ37883.1 - 8.6e-29 99.8 0.0 3.2 8.3 0.0 11.0 10 1 1 11 11 11 11 Ubiquitin-like domain DUF2407 PF10302.9 CDJ37883.1 - 3.7e-26 91.7 0.1 2 9.0 0.0 10.0 1 1 9 10 10 10 9 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 CDJ37883.1 - 5.1e-26 90.3 0.0 0.63 9.9 0.0 10.0 2 1 8 10 10 10 10 Ubiquitin-2 like Rad60 SUMO-like Pr_beta_C PF12465.8 CDJ37883.1 - 2.2e-18 65.3 0.0 18 4.8 0.0 11.0 11 0 0 11 11 11 0 Proteasome beta subunits C terminal Rad60-SLD_2 PF13881.6 CDJ37883.1 - 3.9e-15 55.9 0.1 7.7 6.7 0.0 9.2 2 1 8 10 10 10 2 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.8 CDJ37883.1 - 1.7e-12 47.6 0.1 1e+02 3.4 0.0 9.7 10 0 0 10 10 10 0 Protein of unknown function (DUF2870) BTK PF00779.19 CDJ37883.1 - 8.8e-10 38.2 3.1 1.3e+02 2.5 0.0 10.4 11 0 0 11 11 11 0 BTK motif FucT_N PF18025.1 CDJ37883.1 - 9.6e-09 35.6 0.0 80 3.8 0.0 9.1 8 2 1 10 10 10 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain DUF4850 PF16142.5 CDJ37883.1 - 9.4e-06 25.2 0.1 19 4.7 0.0 5.2 1 1 9 10 10 10 0 Domain of unknown function (DUF4850) DUF211 PF02680.14 CDJ37883.1 - 1.7e-05 24.9 0.0 2.5e+02 1.9 0.0 7.5 7 2 2 9 9 9 0 Uncharacterized ArCR, COG1888 NADH-u_ox-rdase PF10785.9 CDJ37883.1 - 7.8e-05 23.3 0.0 1.4e+02 3.2 0.0 6.7 1 1 7 8 8 8 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit TBSV_P22 PF03558.13 CDJ37883.1 - 0.0007 19.1 0.5 68 2.9 0.0 4.5 1 1 8 9 9 9 0 TBSV core protein P21/P22 Glyco_transf_20 PF00982.21 CDJ37884.1 - 4.3e-149 497.2 6.0 1.2e-124 416.6 0.0 4.4 4 0 0 4 4 4 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CDJ37884.1 - 1.6e-11 43.8 7.8 2.5e-08 33.3 0.0 3.0 2 1 1 3 3 3 2 Trehalose-phosphatase Na_trans_assoc PF06512.13 CDJ37884.1 - 0.0042 17.4 20.0 0.0042 17.4 20.0 6.2 4 3 0 4 4 4 1 Sodium ion transport-associated Med26 PF08711.11 CDJ37885.1 - 6.8e-07 29.2 0.0 6.8e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Zip PF02535.22 CDJ37885.1 - 0.57 9.3 5.9 0.032 13.5 1.1 1.4 2 0 0 2 2 2 0 ZIP Zinc transporter ERM PF00769.19 CDJ37885.1 - 1.2 8.9 38.3 0.95 9.2 21.5 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family UreE_C PF05194.12 CDJ37885.1 - 2.3 8.8 12.9 3.6 8.1 8.8 2.4 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain RNA_polI_A34 PF08208.11 CDJ37885.1 - 2.5 8.1 21.3 9.9 6.2 0.3 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 TFIIA PF03153.13 CDJ37885.1 - 2.6 8.0 31.3 0.3 11.0 19.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 CDJ37885.1 - 2.7 6.0 22.8 0.27 9.3 12.0 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein SelP_N PF04592.14 CDJ37885.1 - 3.2 7.1 17.9 0.059 12.8 10.1 2.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region GAGA_bind PF06217.12 CDJ37885.1 - 5.9 7.1 19.7 2 8.6 11.6 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family DUF1298 PF06974.13 CDJ37886.1 - 8.2e-21 74.5 0.0 1.5e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 CDJ37886.1 - 7.4e-09 35.7 9.9 0.00029 20.7 2.0 3.0 3 0 0 3 3 3 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Adeno_PV PF03910.13 CDJ37886.1 - 0.058 12.1 2.9 0.1 11.3 2.9 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF2681 PF10883.8 CDJ37886.1 - 0.088 13.2 0.5 0.088 13.2 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) LapA_dom PF06305.11 CDJ37886.1 - 0.12 12.2 6.3 0.048 13.5 1.7 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PspB PF06667.12 CDJ37886.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Phage shock protein B HSP70 PF00012.20 CDJ37887.1 - 3.5e-258 857.7 11.2 4e-258 857.5 11.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ37887.1 - 1.9e-20 72.9 2.0 1.8e-19 69.7 0.8 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CDJ37887.1 - 0.00018 21.9 2.8 0.31 11.5 0.1 3.5 3 2 0 3 3 3 2 Cell division protein FtsA Radial_spoke_3 PF06098.11 CDJ37887.1 - 0.0011 18.3 0.8 0.0011 18.3 0.8 1.6 2 0 0 2 2 2 1 Radial spoke protein 3 DDR PF08841.10 CDJ37887.1 - 0.013 14.6 0.2 1.8 7.5 0.1 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 CDJ37887.1 - 0.013 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain SIKE PF05769.11 CDJ37887.1 - 0.081 12.9 0.2 0.081 12.9 0.2 2.0 2 0 0 2 2 2 0 SIKE family CENP-Q PF13094.6 CDJ37887.1 - 0.52 10.5 4.3 8.9 6.5 0.8 2.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit MACPF PF01823.19 CDJ37888.1 - 9.5e-37 127.1 0.0 1.7e-36 126.3 0.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain EF-hand_7 PF13499.6 CDJ37889.1 - 0.0036 17.7 0.7 0.13 12.7 0.0 3.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CDJ37889.1 - 0.013 15.4 0.4 0.33 10.8 0.4 3.1 2 0 0 2 2 2 0 EF-hand domain pair VIT1 PF01988.19 CDJ37889.1 - 0.027 14.3 2.9 0.029 14.2 0.2 2.6 2 0 0 2 2 2 0 VIT family RE_XcyI PF09571.10 CDJ37889.1 - 0.18 11.1 1.3 0.63 9.2 0.2 2.2 2 0 0 2 2 2 0 XcyI restriction endonuclease DEAD PF00270.29 CDJ37890.1 - 3e-35 121.6 0.2 3e-35 121.6 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ37890.1 - 2.3e-06 27.7 0.6 1e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Plasmodium_Vir PF05795.11 CDJ37890.1 - 0.21 11.0 9.4 0.07 12.5 0.2 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Ndc1_Nup PF09531.10 CDJ37890.1 - 2.1 7.0 21.6 1.9 7.1 10.5 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 CDJ37890.1 - 6.6 5.2 11.7 0.32 9.5 1.5 2.2 2 0 0 2 2 2 0 Macoilin family DUF2722 PF10846.8 CDJ37890.1 - 9.7 5.0 26.1 0.028 13.4 8.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) RNase_P_p30 PF01876.16 CDJ37891.1 - 2.2e-18 66.6 0.8 2.8e-16 59.6 1.0 3.1 3 1 0 3 3 3 1 RNase P subunit p30 SUIM_assoc PF16619.5 CDJ37891.1 - 0.015 15.4 8.2 2.8 8.1 0.2 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 HA2 PF04408.23 CDJ37893.1 - 3.9e-19 68.9 2.0 4.4e-19 68.8 0.1 2.0 2 1 0 2 2 2 1 Helicase associated domain (HA2) GTP_EFTU PF00009.27 CDJ37895.1 - 1.7e-41 141.9 0.0 2.4e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDJ37895.1 - 1.4e-22 80.1 0.0 4.4e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDJ37895.1 - 2e-05 24.9 0.2 6.3e-05 23.3 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ37895.1 - 0.0047 17.0 0.1 0.018 15.1 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.15 CDJ37895.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.5 3 0 0 3 3 3 0 Ataxin-2 C-terminal region K_channel_TID PF07941.11 CDJ37896.1 - 0.0048 17.3 1.9 0.0048 17.3 1.9 5.0 4 2 1 5 5 5 2 Potassium channel Kv1.4 tandem inactivation domain Pkinase PF00069.25 CDJ37897.1 - 2.6e-59 200.7 0.0 9.8e-59 198.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37897.1 - 9.6e-29 100.4 0.0 1.4e-21 76.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 CDJ37897.1 - 4.6e-07 29.7 0.9 0.00068 19.3 0.0 2.9 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CDJ37897.1 - 1.6e-06 27.7 0.1 0.015 14.6 0.0 3.2 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 CDJ37897.1 - 0.00012 21.0 0.0 0.00012 21.0 0.0 2.5 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CDJ37897.1 - 0.0012 18.9 3.3 0.065 13.1 0.0 2.9 3 1 1 4 4 4 2 Phosphotransferase enzyme family RIO1 PF01163.22 CDJ37897.1 - 0.0016 18.1 1.6 0.0022 17.6 0.0 1.9 3 0 0 3 3 3 1 RIO1 family Haspin_kinase PF12330.8 CDJ37897.1 - 0.048 12.6 0.1 0.048 12.6 0.1 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CDJ37897.1 - 0.086 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RAP1 PF07218.11 CDJ37897.1 - 0.16 10.2 5.9 0.2 9.9 5.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4718 PF15842.5 CDJ37897.1 - 0.42 10.4 6.2 0.86 9.4 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) UBN_AB PF14075.6 CDJ37897.1 - 1 9.1 11.7 0.69 9.6 1.9 2.2 2 0 0 2 2 2 0 Ubinuclein conserved middle domain GTP_EFTU PF00009.27 CDJ37898.1 - 4.5e-22 78.5 0.0 9.9e-22 77.4 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ37898.1 - 1.7e-05 24.9 0.0 3.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CDJ37898.1 - 0.08 13.3 0.2 0.89 10.0 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 2 SUIM_assoc PF16619.5 CDJ37898.1 - 3.5 7.8 6.7 1.1 9.4 2.8 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AAA_5 PF07728.14 CDJ37901.1 - 4.9e-103 340.8 0.0 2.9e-20 72.7 0.0 10.3 9 1 0 9 9 9 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CDJ37901.1 - 1.1e-27 96.3 6.8 3.7e-13 49.6 0.4 5.6 5 0 0 5 5 4 2 Midasin AAA lid domain AAA PF00004.29 CDJ37901.1 - 5e-22 78.8 0.0 0.0044 17.4 0.0 7.2 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 CDJ37901.1 - 1.4e-21 76.5 0.0 3.8e-21 75.1 0.0 1.8 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_3 PF07726.11 CDJ37901.1 - 2.3e-17 63.1 0.0 0.0081 16.0 0.0 7.3 8 0 0 8 8 6 4 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 CDJ37901.1 - 1.6e-16 60.5 0.0 6.7e-06 26.2 0.0 5.8 5 0 0 5 5 5 4 Dynein heavy chain region D6 P-loop domain TsaE PF02367.17 CDJ37901.1 - 3e-13 49.9 1.8 0.074 13.1 0.3 6.5 6 0 0 6 6 6 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CDJ37901.1 - 2.3e-12 46.8 0.0 0.25 10.8 0.0 6.3 6 0 0 6 6 6 3 P-loop containing dynein motor region AAA_22 PF13401.6 CDJ37901.1 - 3e-10 40.5 22.4 0.086 13.1 0.0 9.5 10 0 0 10 10 6 3 AAA domain AAA_18 PF13238.6 CDJ37901.1 - 1.3e-09 38.6 0.0 1.1 9.8 0.0 7.1 6 0 0 6 6 6 1 AAA domain NACHT PF05729.12 CDJ37901.1 - 1.3e-07 31.7 4.6 1.1 9.2 0.0 7.2 6 0 0 6 6 6 2 NACHT domain AAA_33 PF13671.6 CDJ37901.1 - 7.3e-07 29.4 35.4 6.2e-05 23.2 0.0 8.6 9 0 0 9 9 6 3 AAA domain Sigma54_activat PF00158.26 CDJ37901.1 - 1.1e-06 28.4 2.0 4.9 6.8 0.0 6.7 7 0 0 7 7 7 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CDJ37901.1 - 1.9e-06 27.4 8.2 0.11 11.9 0.1 7.4 7 1 0 8 8 8 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CDJ37901.1 - 2.6e-06 26.8 1.6 0.087 12.0 0.0 5.7 6 0 0 6 6 6 1 Protein of unknown function (DUF815) AAA_6 PF12774.7 CDJ37901.1 - 1.9e-05 23.8 0.0 1.3 7.9 0.0 5.3 5 0 0 5 5 5 1 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 CDJ37901.1 - 0.00012 22.4 0.0 89 3.5 0.0 6.1 6 0 0 6 6 6 0 RNA helicase AAA_14 PF13173.6 CDJ37901.1 - 0.00018 21.6 0.0 0.18 11.9 0.0 4.6 5 0 0 5 5 4 1 AAA domain AAA_8 PF12780.7 CDJ37901.1 - 0.00022 20.7 0.0 0.06 12.7 0.0 4.2 5 0 0 5 5 4 1 P-loop containing dynein motor region D4 RuvB_N PF05496.12 CDJ37901.1 - 0.0009 19.0 0.2 27 4.5 0.0 6.1 7 0 0 7 7 7 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CDJ37901.1 - 0.0012 18.9 0.7 4.6 7.1 0.0 4.8 6 0 0 6 6 5 1 Rad17 P-loop domain AAA_29 PF13555.6 CDJ37901.1 - 0.0045 16.7 6.7 29 4.5 0.0 6.4 7 0 0 7 7 6 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CDJ37901.1 - 0.019 15.5 21.8 3.6 8.1 0.0 8.1 8 0 0 8 8 6 0 ABC transporter Viral_helicase1 PF01443.18 CDJ37901.1 - 0.024 14.4 0.0 1.2 8.8 0.0 3.4 4 0 0 4 4 3 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 CDJ37901.1 - 0.024 15.0 0.1 0.024 15.0 0.1 18.0 12 5 2 14 14 11 0 AAA ATPase domain dNK PF01712.19 CDJ37901.1 - 0.067 13.0 0.1 2.6 7.9 0.0 3.2 4 0 0 4 4 3 0 Deoxynucleoside kinase Sigma54_activ_2 PF14532.6 CDJ37901.1 - 0.067 13.3 20.7 1.4 9.1 0.0 7.8 8 0 0 8 8 6 0 Sigma-54 interaction domain Roc PF08477.13 CDJ37901.1 - 0.15 12.3 0.5 65 3.8 0.0 3.9 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase NDK PF00334.19 CDJ37902.1 - 3.2e-28 98.4 0.0 4.7e-26 91.4 0.0 2.2 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 CDJ37902.1 - 0.00014 21.6 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 DUF1126 PH-like domain Peptidase_S21 PF00716.17 CDJ37902.1 - 2 8.0 9.3 2.5 7.7 6.9 1.9 2 0 0 2 2 2 0 Assemblin (Peptidase family S21) Fe-S_biosyn PF01521.20 CDJ37903.1 - 1.3e-08 35.0 0.0 1.8e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis Macoilin PF09726.9 CDJ37903.1 - 0.23 10.0 5.4 0.34 9.4 5.4 1.2 1 0 0 1 1 1 0 Macoilin family DUF4614 PF15391.6 CDJ37903.1 - 1.4 8.9 9.3 2.8 7.9 9.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 CDJ37903.1 - 1.5 7.6 7.4 1.8 7.4 7.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RCC1 PF00415.18 CDJ37904.1 - 6.7e-30 103.5 17.1 1.7e-09 38.2 0.6 7.0 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ37904.1 - 2.3e-24 84.6 21.9 1.8e-09 37.1 1.1 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Ribosomal_L7Ae PF01248.26 CDJ37905.1 - 6.2e-19 67.5 0.0 1.4e-18 66.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SR-25 PF10500.9 CDJ37905.1 - 0.17 11.4 11.6 0.26 10.9 11.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4603 PF15376.6 CDJ37905.1 - 0.73 7.2 5.6 0.94 6.8 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Herpes_BLLF1 PF05109.13 CDJ37907.1 - 0.12 10.3 1.3 0.17 9.8 1.3 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) SUIM_assoc PF16619.5 CDJ37911.1 - 4.8 7.3 11.6 0.42 10.7 0.7 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 K_channel_TID PF07941.11 CDJ37912.1 - 0.0022 18.4 11.2 0.0032 17.9 11.2 1.3 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain RskA PF10099.9 CDJ37912.1 - 0.0027 18.0 4.8 0.0032 17.8 4.8 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA NICE-1 PF15845.5 CDJ37912.1 - 0.33 11.8 9.2 0.49 11.2 9.2 1.3 1 1 0 1 1 1 0 Cysteine-rich C-terminal 1 family DUF4587 PF15248.6 CDJ37914.1 - 0.07 13.9 1.2 0.8 10.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) LRR_6 PF13516.6 CDJ37915.1 - 7.7e-12 44.3 15.7 0.049 13.7 0.0 9.9 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.7 CDJ37915.1 - 0.0033 17.8 18.9 0.29 11.6 0.3 5.4 3 3 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDJ37915.1 - 0.18 12.5 7.9 82 4.4 0.2 6.1 6 1 0 6 6 6 0 Leucine Rich Repeat BAF1_ABF1 PF04684.13 CDJ37915.1 - 5.8 5.9 5.6 5.4 5.9 5.6 1.3 1 1 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Shadoo PF14999.6 CDJ37916.1 - 0.0039 17.3 1.3 0.0039 17.3 1.3 2.4 2 0 0 2 2 2 1 Shadow of prion protein, neuroprotective Phage_pRha PF09669.10 CDJ37916.1 - 0.23 12.1 2.0 2.1 8.9 2.6 2.3 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) SRP54 PF00448.22 CDJ37917.1 - 2.3e-76 255.8 0.1 4.5e-76 254.9 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CDJ37917.1 - 1.9e-31 108.6 5.1 4.1e-31 107.5 0.8 2.7 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.19 CDJ37917.1 - 1.7e-13 50.6 0.3 1.6e-12 47.4 0.1 2.6 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 CDJ37917.1 - 1.3e-05 25.4 0.0 3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CDJ37917.1 - 3.5e-05 23.5 0.2 0.00023 20.8 0.2 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CDJ37917.1 - 4.1e-05 24.0 1.0 0.00033 21.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 CDJ37917.1 - 0.00015 21.6 1.8 0.00034 20.4 0.1 2.5 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 CDJ37917.1 - 0.00028 19.9 0.6 0.0024 16.9 0.0 2.6 4 0 0 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 CDJ37917.1 - 0.00029 21.3 0.0 0.0015 19.0 0.0 2.3 1 0 0 1 1 1 1 AAA domain DRE2_N PF16803.5 CDJ37917.1 - 0.00086 19.6 0.0 0.1 12.8 0.0 2.5 2 0 0 2 2 2 1 Fe-S cluster assembly protein DRE2 N-terminus AAA_22 PF13401.6 CDJ37917.1 - 0.002 18.4 0.4 0.019 15.2 0.0 2.8 2 2 1 3 3 3 1 AAA domain Zeta_toxin PF06414.12 CDJ37917.1 - 0.0045 16.3 0.1 0.0087 15.4 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.23 CDJ37917.1 - 0.0053 16.8 0.0 0.013 15.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRPRB PF09439.10 CDJ37917.1 - 0.0063 16.0 0.3 2.2 7.7 0.0 2.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit APS_kinase PF01583.20 CDJ37917.1 - 0.0073 16.2 0.2 0.019 14.9 0.0 1.7 2 0 0 2 2 1 1 Adenylylsulphate kinase ResIII PF04851.15 CDJ37917.1 - 0.014 15.4 0.7 0.08 12.9 0.7 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4310 PF14187.6 CDJ37917.1 - 0.019 14.6 0.3 0.033 13.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) ATPase PF06745.13 CDJ37917.1 - 0.027 13.8 0.0 0.081 12.3 0.0 1.9 1 0 0 1 1 1 0 KaiC Methyltransf_24 PF13578.6 CDJ37917.1 - 0.028 15.4 0.1 0.077 14.0 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain AAA_28 PF13521.6 CDJ37917.1 - 0.032 14.5 0.1 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 CDJ37917.1 - 0.039 13.7 0.2 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 CDJ37917.1 - 0.046 13.8 0.4 0.37 10.9 0.2 2.6 2 1 0 2 2 1 0 50S ribosome-binding GTPase MobB PF03205.14 CDJ37917.1 - 0.047 13.6 0.1 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DpnI_C PF17726.1 CDJ37917.1 - 0.073 13.2 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Dam-replacing HTH domain Thymidylate_kin PF02223.17 CDJ37917.1 - 0.077 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Thymidylate kinase Herpes_LP PF03363.13 CDJ37917.1 - 0.1 12.4 0.8 0.18 11.6 0.8 1.3 1 0 0 1 1 1 0 Herpesvirus leader protein PduV-EutP PF10662.9 CDJ37917.1 - 0.11 12.2 0.4 4 7.2 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_31 PF13614.6 CDJ37917.1 - 0.11 12.3 0.4 1.8 8.4 0.0 2.5 1 1 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 CDJ37917.1 - 0.56 9.3 3.6 0.87 8.7 0.1 2.7 2 1 0 3 3 3 0 Anion-transporting ATPase Phage_BR0599 PF09356.10 CDJ37918.1 - 0.19 12.1 0.4 0.5 10.7 0.4 1.6 1 0 0 1 1 1 0 Phage conserved hypothetical protein BR0599 DUF572 PF04502.13 CDJ37918.1 - 0.2 11.3 11.4 0.26 10.8 11.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S64 PF08192.11 CDJ37918.1 - 5.2 5.4 10.6 1.9 6.9 0.7 2.0 1 1 1 2 2 2 0 Peptidase family S64 Brix PF04427.18 CDJ37920.1 - 3.8e-32 112.0 0.8 1.2e-31 110.4 0.8 1.8 1 1 0 1 1 1 1 Brix domain SR-25 PF10500.9 CDJ37920.1 - 0.0053 16.4 3.3 0.0053 16.4 3.3 5.7 4 2 0 5 5 5 2 Nuclear RNA-splicing-associated protein SepSecS PF05889.13 CDJ37922.1 - 0.08 11.6 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Hid1 PF12722.7 CDJ37922.1 - 0.24 9.5 11.9 0.3 9.2 11.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PSK_trans_fac PF07704.11 CDJ37922.1 - 0.41 11.4 0.0 0.41 11.4 0.0 2.2 2 0 0 2 2 1 0 Rv0623-like transcription factor PhnG PF06754.12 CDJ37922.1 - 0.59 10.1 6.6 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnG CDC45 PF02724.14 CDJ37922.1 - 0.87 7.8 9.6 1.1 7.4 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ37922.1 - 1.8 8.3 13.8 2.4 7.9 13.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4175 PF13779.6 CDJ37922.1 - 2.1 6.2 18.3 2.3 6.0 18.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CobT PF06213.12 CDJ37922.1 - 2.9 7.2 24.5 4.2 6.7 24.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT eIF-3_zeta PF05091.12 CDJ37922.1 - 3 6.7 11.8 3.7 6.4 11.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Paf1 PF03985.13 CDJ37922.1 - 3.3 6.6 18.1 4.5 6.2 18.1 1.2 1 0 0 1 1 1 0 Paf1 PTPRCAP PF15713.5 CDJ37922.1 - 3.4 8.0 17.3 5.8 7.2 17.3 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SpoIIP PF07454.11 CDJ37922.1 - 3.7 6.9 10.9 5.2 6.4 10.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) VIR_N PF15912.5 CDJ37922.1 - 3.7 7.1 10.7 5.2 6.6 10.7 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Neur_chan_memb PF02932.16 CDJ37922.1 - 5.5 7.0 7.6 7.9 6.5 7.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.6 CDJ37922.1 - 6.6 6.6 19.4 10 6.0 19.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Spt20 PF12090.8 CDJ37922.1 - 9.4 5.8 25.4 15 5.1 25.4 1.3 1 0 0 1 1 1 0 Spt20 family GREB1 PF15782.5 CDJ37923.1 - 0.25 8.4 48.9 0.3 8.2 48.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF572 PF04502.13 CDJ37923.1 - 9.3 5.8 44.4 12 5.4 44.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) baeRF_family10 PF18854.1 CDJ37924.1 - 0.038 14.2 0.2 0.038 14.2 0.2 2.1 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 CDK2AP PF09806.9 CDJ37924.1 - 0.13 12.3 24.2 0.17 11.9 24.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Apt1 PF10351.9 CDJ37924.1 - 1.6 7.5 13.7 1.9 7.2 13.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIA PF03153.13 CDJ37924.1 - 2.3 8.1 34.9 3.2 7.6 34.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ALMT PF11744.8 CDJ37924.1 - 6.6 5.4 12.2 7.5 5.3 12.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RskA PF10099.9 CDJ37925.1 - 5.7 7.2 42.7 0.12 12.7 20.4 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ37925.1 - 8.7 6.2 30.1 10 6.0 30.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CorA PF01544.18 CDJ37926.1 - 1.8 7.8 7.5 3.8 6.8 7.5 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Transformer PF06495.11 CDJ37927.1 - 8.6 6.4 16.5 0.039 14.0 7.8 1.5 2 0 0 2 2 2 0 Fruit fly transformer protein His_Phos_2 PF00328.22 CDJ37928.1 - 0.016 14.6 4.1 0.02 14.2 4.1 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Nha1_C PF08619.10 CDJ37928.1 - 4.3 6.4 13.4 5.4 6.1 13.4 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus TFIIA PF03153.13 CDJ37928.1 - 6.4 6.7 13.2 8.8 6.2 13.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mito_fiss_reg PF05308.11 CDJ37929.1 - 0.0095 16.0 1.9 0.0095 16.0 1.9 1.8 2 0 0 2 2 2 1 Mitochondrial fission regulator GREB1 PF15782.5 CDJ37929.1 - 4.8 4.2 5.3 5.9 3.9 5.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AF-4 PF05110.13 CDJ37929.1 - 8.8 4.3 24.3 1.4 6.9 4.0 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Med31 PF05669.12 CDJ37930.1 - 4.2e-24 84.4 4.7 4.2e-24 84.4 4.7 2.7 3 0 0 3 3 3 1 SOH1 RskA PF10099.9 CDJ37931.1 - 0.0039 17.5 0.0 0.0039 17.5 0.0 14.5 8 4 3 12 12 12 3 Anti-sigma-K factor rskA Aminotran_5 PF00266.19 CDJ37932.1 - 5.9e-31 107.8 0.0 1.7e-29 102.9 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-V Tho2 PF11262.8 CDJ37934.1 - 3.1e-60 203.9 4.9 1.2e-41 142.9 0.0 2.6 3 0 0 3 3 3 2 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 CDJ37934.1 - 4e-19 68.7 12.4 7.1e-12 44.8 0.0 4.6 4 1 0 4 4 4 3 THO complex subunit 2 N-terminus Thoc2 PF11732.8 CDJ37934.1 - 0.087 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Leu_zip PF15294.6 CDJ37934.1 - 0.11 12.0 5.0 0.26 10.8 5.0 1.6 1 0 0 1 1 1 0 Leucine zipper ABC2_membrane PF01061.24 CDJ37936.1 - 1.5e-34 119.2 20.6 1.5e-34 119.2 20.6 1.5 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 CDJ37936.1 - 2.1e-26 93.1 0.1 1.9e-25 90.0 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CDJ37936.1 - 6.2e-08 32.8 0.0 0.0022 17.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CDJ37936.1 - 2.3e-05 24.8 0.0 2.3e-05 24.8 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 CDJ37936.1 - 3.5e-05 23.1 17.2 3.5e-05 23.1 17.2 2.2 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_22 PF13401.6 CDJ37936.1 - 0.00024 21.4 0.3 0.0031 17.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CDJ37936.1 - 0.00035 20.5 0.5 0.0007 19.5 0.5 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CDJ37936.1 - 0.0012 18.6 0.1 0.0024 17.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 CDJ37936.1 - 0.0012 18.0 0.1 0.002 17.2 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 CDJ37936.1 - 0.0022 18.6 3.0 0.0064 17.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CDJ37936.1 - 0.0068 16.0 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 CDJ37936.1 - 0.013 14.9 0.1 0.24 10.8 0.1 2.3 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 CDJ37936.1 - 0.016 15.4 0.2 0.016 15.4 0.2 2.1 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 CDJ37936.1 - 0.02 15.4 0.0 0.048 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CDJ37936.1 - 0.022 14.8 0.3 0.049 13.7 0.3 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 CDJ37936.1 - 0.023 14.6 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 CDJ37936.1 - 0.03 14.7 0.1 0.1 13.0 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 CDJ37936.1 - 0.031 13.9 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 CDJ37936.1 - 0.033 13.9 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDJ37936.1 - 0.044 13.5 0.1 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CDJ37936.1 - 0.047 13.6 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain SRP54 PF00448.22 CDJ37936.1 - 0.051 13.2 0.1 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 CDJ37936.1 - 0.051 13.5 0.8 0.12 12.3 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 CDJ37936.1 - 0.087 13.0 0.1 0.087 13.0 0.1 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 CDJ37936.1 - 0.18 11.4 0.0 0.51 9.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Spt20 PF12090.8 CDJ37936.1 - 0.43 10.2 6.5 0.74 9.4 6.5 1.3 1 0 0 1 1 1 0 Spt20 family Dynamin_N PF00350.23 CDJ37936.1 - 0.97 9.5 3.6 0.6 10.1 0.3 2.1 2 0 0 2 2 2 0 Dynamin family SUIM_assoc PF16619.5 CDJ37937.1 - 0.01 15.9 1.0 0.022 14.8 1.0 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4781 PF16013.5 CDJ37937.1 - 5.8 5.6 6.4 16 4.2 6.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Bax1-I PF01027.20 CDJ37938.1 - 3.8e-12 46.5 10.7 4.5e-12 46.2 10.7 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CPP1-like PF11833.8 CDJ37938.1 - 0.093 12.4 4.5 0.11 12.1 4.5 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like IMD PF08397.11 CDJ37939.1 - 0.028 13.8 11.0 0.23 10.8 8.0 2.2 2 0 0 2 2 2 0 IRSp53/MIM homology domain MPS2 PF17060.5 CDJ37939.1 - 0.52 9.5 7.6 0.41 9.9 6.1 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF3086 PF11285.8 CDJ37939.1 - 0.65 9.0 9.9 0.016 14.3 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) L31 PF09784.9 CDJ37939.1 - 1.4 9.4 5.7 19 5.8 5.7 2.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF1754 PF08555.10 CDJ37940.1 - 1.2e-07 32.4 13.5 0.00019 22.2 4.2 2.4 1 1 0 2 2 2 2 Eukaryotic family of unknown function (DUF1754) Sld5 PF05916.11 CDJ37940.1 - 0.042 14.3 1.4 0.044 14.3 0.3 1.7 2 0 0 2 2 2 0 GINS complex protein HTH_32 PF13565.6 CDJ37940.1 - 0.24 12.0 4.1 0.18 12.5 0.7 2.3 2 1 0 2 2 2 0 Homeodomain-like domain Cation_ATPase_C PF00689.21 CDJ37942.1 - 2.1e-52 177.5 2.4 4.1e-52 176.5 2.4 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CDJ37942.1 - 3.7e-50 170.0 2.0 3e-49 167.0 0.2 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ37942.1 - 1.5e-20 74.4 3.9 3.5e-19 69.9 3.9 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ37942.1 - 1e-19 70.4 0.0 2e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CDJ37942.1 - 1e-18 66.8 0.1 4.9e-18 64.6 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDJ37942.1 - 1.4e-05 25.0 0.5 7.7e-05 22.6 0.5 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ37942.1 - 0.0024 18.3 0.0 0.0098 16.3 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase CLN3 PF02487.17 CDJ37943.1 - 0.0039 16.3 1.1 0.0095 15.0 1.1 1.5 1 0 0 1 1 1 1 CLN3 protein FAM176 PF14851.6 CDJ37943.1 - 0.35 10.5 3.2 0.2 11.3 0.1 2.1 2 0 0 2 2 2 0 FAM176 family DUF4834 PF16118.5 CDJ37943.1 - 1.5 9.8 7.1 0.37 11.8 1.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Methyltrans_RNA PF04452.14 CDJ37944.1 - 3.3e-33 114.9 0.0 1.7e-17 63.5 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase AbiEi_3 PF11459.8 CDJ37944.1 - 0.0027 17.4 0.1 0.0053 16.5 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Presenilin PF01080.17 CDJ37944.1 - 0.52 9.0 4.7 0.29 9.9 1.6 1.8 2 0 0 2 2 2 0 Presenilin RskA PF10099.9 CDJ37944.1 - 4.8 7.5 26.4 0.37 11.1 5.8 3.0 2 1 0 2 2 2 0 Anti-sigma-K factor rskA RsfS PF02410.15 CDJ37945.1 - 6.7e-13 48.9 0.0 1.4e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Ribosomal_L19e PF01280.20 CDJ37945.1 - 0.17 12.0 0.6 0.33 11.0 0.6 1.4 1 0 0 1 1 1 0 Ribosomal protein L19e Apt1 PF10351.9 CDJ37945.1 - 0.96 8.2 11.0 0.026 13.4 4.6 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain zf-C3HC4 PF00097.25 CDJ37946.1 - 0.00065 19.5 8.8 0.00065 19.5 8.8 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ37946.1 - 2.5 8.1 21.1 9.6 6.3 21.1 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ37946.1 - 4 7.4 19.1 0.23 11.3 11.6 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ37946.1 - 5.1 7.5 21.1 0.095 13.1 12.2 2.2 2 0 0 2 2 2 0 Ring finger domain RAP PF08373.10 CDJ37947.1 - 1.1e-16 60.6 0.0 1.7e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 CDJ37947.1 - 2.9e-05 24.2 0.1 5.3e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 REase_MTES_1575 Ribosomal_60s PF00428.19 CDJ37948.1 - 0.55 10.9 27.8 2.3 8.9 1.7 3.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein Rnk_N PF14760.6 CDJ37948.1 - 0.83 10.2 5.6 0.56 10.7 1.4 2.7 2 0 0 2 2 2 0 Rnk N-terminus LisH_2 PF16045.5 CDJ37949.1 - 0.0078 15.2 0.3 0.017 14.1 0.3 1.6 1 0 0 1 1 1 1 LisH RNB PF00773.19 CDJ37949.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 RNB domain DUF3654 PF12376.8 CDJ37949.1 - 0.072 13.3 0.0 0.081 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) PilJ PF13675.6 CDJ37949.1 - 0.18 11.8 0.0 0.23 11.5 0.0 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term MFS_1 PF07690.16 CDJ37950.1 - 2.8e-08 33.1 3.9 2.8e-08 33.1 3.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily GET2 PF08690.10 CDJ37950.1 - 0.55 9.8 4.2 1 9.0 0.9 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 SUIM_assoc PF16619.5 CDJ37950.1 - 3.6 7.7 20.9 0.44 10.6 0.2 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ37950.1 - 8.5 5.9 19.6 0.092 12.3 5.8 2.1 2 0 0 2 2 2 0 Spt20 family ribosomal_L24 PF17136.4 CDJ37951.1 - 9.7e-09 35.5 0.0 1.7e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 CDJ37951.1 - 0.00044 20.1 0.7 0.00076 19.3 0.1 1.7 2 0 0 2 2 2 1 KOW motif SH3_2 PF07653.17 CDJ37951.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Couple_hipA PF13657.6 CDJ37952.1 - 0.027 15.1 3.6 0.035 14.7 1.8 2.2 2 1 0 2 2 2 0 HipA N-terminal domain DUF4630 PF15443.6 CDJ37952.1 - 0.29 11.3 2.8 0.55 10.4 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) Vps54 PF07928.12 CDJ37952.1 - 0.66 10.4 7.4 7.7 7.0 0.5 2.2 2 0 0 2 2 2 0 Vps54-like protein V_ATPase_I PF01496.19 CDJ37952.1 - 0.73 7.7 6.2 0.91 7.4 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4834 PF16118.5 CDJ37952.1 - 0.77 10.8 2.8 6.4 7.8 0.6 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF4207 PF13904.6 CDJ37952.1 - 4.9 6.8 12.7 0.28 10.9 5.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) SAPS PF04499.15 CDJ37953.1 - 0.031 13.1 0.8 0.041 12.7 0.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Cwf_Cwc_15 PF04889.12 CDJ37953.1 - 2.8 7.6 7.2 1.2 8.8 4.5 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Thiolase_N PF00108.23 CDJ37954.1 - 3.6e-36 124.9 0.0 1.1e-12 47.8 0.0 3.1 3 0 0 3 3 3 3 Thiolase, N-terminal domain Thiolase_C PF02803.18 CDJ37954.1 - 1.4e-28 99.1 0.1 5.3e-28 97.1 0.0 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 CDJ37954.1 - 0.16 11.8 1.6 0.93 9.4 0.1 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SUIM_assoc PF16619.5 CDJ37958.1 - 0.019 15.0 0.2 0.019 15.0 0.2 17.6 13 4 2 15 15 15 0 Unstructured region C-term to UIM in Ataxin3 RAP PF08373.10 CDJ37959.1 - 2.5e-12 46.7 0.0 7.5e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 RAP domain FF PF01846.19 CDJ37960.1 - 0.005 17.0 0.1 0.083 13.1 0.1 2.2 2 0 0 2 2 2 1 FF domain VSG_B PF13206.6 CDJ37960.1 - 0.08 12.2 14.3 0.097 11.9 14.3 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain LMBR1 PF04791.16 CDJ37960.1 - 3.3 6.5 5.5 3.6 6.4 5.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Acetyltransf_8 PF13523.6 CDJ37960.1 - 4.4 7.0 10.8 0.14 11.9 4.2 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GREB1 PF15782.5 CDJ37960.1 - 4.6 4.2 12.8 5 4.1 12.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HSP70 PF00012.20 CDJ37960.1 - 9.9 4.2 14.7 11 4.0 14.7 1.1 1 0 0 1 1 1 0 Hsp70 protein Ala_racemase_N PF01168.20 CDJ37963.1 - 4.9e-17 62.3 4.8 4.9e-17 62.3 4.8 2.1 1 1 1 2 2 2 1 Alanine racemase, N-terminal domain DUF1048 PF06304.11 CDJ37963.1 - 0.09 13.2 0.1 9.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1048) FoP_duplication PF13865.6 CDJ37964.1 - 0.003 18.1 0.0 0.0042 17.6 0.0 1.2 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Ribosomal_60s PF00428.19 CDJ37964.1 - 0.065 13.8 5.8 0.068 13.8 5.8 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Atg8 PF02991.16 CDJ37965.1 - 8.1e-33 112.7 0.1 1.5e-32 111.9 0.1 1.4 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CDJ37965.1 - 2.6e-05 24.6 0.1 7.6e-05 23.0 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 MMR1 PF08505.10 CDJ37966.1 - 1 9.6 21.8 1.4 9.2 21.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.13 CDJ37966.1 - 1.2 9.1 41.2 0.12 12.3 37.0 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ37966.1 - 1.3 9.1 11.7 2.2 8.4 11.7 1.4 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.9 CDJ37966.1 - 1.4 7.1 24.6 1.8 6.7 24.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.13 CDJ37966.1 - 1.4 9.5 27.6 0.095 13.4 22.0 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4638 PF15472.6 CDJ37966.1 - 1.6 8.4 10.2 2.3 7.9 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF913 PF06025.12 CDJ37966.1 - 3.1 6.7 9.5 65 2.3 12.3 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) V_ATPase_I PF01496.19 CDJ37966.1 - 3.1 5.6 11.2 3.8 5.3 11.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF572 PF04502.13 CDJ37966.1 - 3.4 7.2 20.6 4.7 6.7 20.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) eIF-3_zeta PF05091.12 CDJ37966.1 - 4.2 6.2 18.6 5.6 5.8 18.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 CDJ37966.1 - 4.6 6.8 42.4 6.9 6.2 42.4 1.2 1 0 0 1 1 1 0 Spt20 family RR_TM4-6 PF06459.12 CDJ37966.1 - 5.8 6.6 18.6 8.6 6.1 18.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ37966.1 - 8.5 6.3 14.2 12 5.8 14.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DEAD PF00270.29 CDJ37967.1 - 9.2e-46 155.8 0.0 3.5e-45 153.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ37967.1 - 2.2e-31 108.5 2.2 2.3e-31 108.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pyr_redox_2 PF07992.14 CDJ37968.1 - 1.3e-16 60.7 0.0 1.7e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 CDJ37968.1 - 1.8e-07 31.6 0.1 4.1e-06 27.3 0.0 2.7 3 0 0 3 3 3 1 Reductase C-terminal FAD_binding_2 PF00890.24 CDJ37968.1 - 0.00099 18.3 0.1 0.0019 17.3 0.0 1.5 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 CDJ37968.1 - 0.0016 19.0 0.0 0.0031 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDJ37968.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 CDJ37968.1 - 0.026 13.6 0.0 0.053 12.6 0.0 1.5 1 1 1 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 CDJ37968.1 - 0.11 11.2 0.0 0.44 9.2 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein DUF3273 PF11677.8 CDJ37969.1 - 8.7e-29 100.6 7.4 1.1e-28 100.3 7.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Claudin_3 PF06653.11 CDJ37969.1 - 0.016 15.2 5.9 0.016 15.2 5.9 1.7 2 0 0 2 2 2 0 Tight junction protein, Claudin-like DUF4271 PF14093.6 CDJ37969.1 - 0.049 13.5 8.3 0.038 13.9 5.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) NDK PF00334.19 CDJ37970.1 - 5.6e-54 181.8 0.0 6.5e-54 181.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 CDJ37970.1 - 0.064 13.8 0.0 0.097 13.2 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ PAT1 PF09770.9 CDJ37971.1 - 0.14 10.4 34.9 0.16 10.2 34.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YjeF_N PF03853.15 CDJ37971.1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.4 1 1 1 2 2 1 0 YjeF-related protein N-terminus SLC12 PF03522.15 CDJ37971.1 - 0.72 8.8 18.9 0.88 8.5 18.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4411 PF14367.6 CDJ37971.1 - 0.92 9.4 10.5 1.3 8.9 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) ABC2_membrane_3 PF12698.7 CDJ37971.1 - 1.9 7.5 7.1 2.2 7.3 7.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein SID-1_RNA_chan PF13965.6 CDJ37971.1 - 2.9 6.2 5.0 3.1 6.1 5.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 CDJ37971.1 - 3.9 6.6 4.9 4.2 6.5 4.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Caldesmon PF02029.15 CDJ37971.1 - 4 6.1 23.8 5.2 5.7 23.8 1.1 1 0 0 1 1 1 0 Caldesmon Endostatin PF06482.11 CDJ37971.1 - 4.3 6.7 18.7 5.1 6.5 18.7 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Asp-B-Hydro_N PF05279.11 CDJ37971.1 - 4.9 7.2 18.7 7 6.7 18.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CCSAP PF15748.5 CDJ37971.1 - 5.4 7.1 19.3 7.1 6.7 19.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated MtaB PF12176.8 CDJ37971.1 - 8.1 5.1 7.8 10 4.8 7.8 1.0 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit U79_P34 PF03064.16 CDJ37972.1 - 2.2 7.6 8.2 2.3 7.5 8.2 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TPR_2 PF07719.17 CDJ37973.1 - 0.011 15.8 0.5 0.011 15.8 0.5 9.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ37973.1 - 0.14 12.0 0.1 0.14 12.0 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Phage_holin_5_1 PF06946.11 CDJ37973.1 - 0.32 11.4 0.7 0.84 10.1 0.7 1.6 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 TPR_8 PF13181.6 CDJ37973.1 - 3.2 8.2 9.9 2.4 8.6 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat GCP_C_terminal PF04130.13 CDJ37974.1 - 3.3e-22 79.3 4.1 3.3e-22 79.3 4.1 2.5 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CDJ37974.1 - 1.6e-15 57.6 0.0 1.6e-15 57.6 0.0 2.2 3 0 0 3 3 3 1 Gamma tubulin complex component N-terminal Atypical_Card PF18461.1 CDJ37975.1 - 0.033 14.4 0.1 0.047 13.9 0.1 1.3 1 1 0 1 1 1 0 Atypical caspase recruitment domain GAS PF13851.6 CDJ37976.1 - 1.2e-29 103.1 22.4 1.2e-29 103.1 22.4 2.6 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 CDJ37976.1 - 1.9e-05 24.6 21.2 1.9e-05 24.6 21.2 2.9 1 1 2 3 3 3 1 Coiled-coil region of CCDC155 or KASH XhlA PF10779.9 CDJ37976.1 - 0.068 13.4 0.8 0.068 13.4 0.8 4.2 4 0 0 4 4 4 0 Haemolysin XhlA DUF812 PF05667.11 CDJ37976.1 - 0.57 9.0 45.6 0.38 9.6 31.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF812) GRIM-19 PF06212.12 CDJ37976.1 - 0.7 9.8 3.6 2.2 8.2 3.6 1.9 1 0 0 1 1 1 0 GRIM-19 protein DNA_methylase PF00145.17 CDJ37977.1 - 4.4e-36 124.9 0.0 9.1e-35 120.6 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Band_3_cyto PF07565.13 CDJ37977.1 - 3.9 7.2 7.0 13 5.5 7.0 1.8 1 1 0 1 1 1 0 Band 3 cytoplasmic domain Suf PF05843.14 CDJ37977.1 - 8.6 6.2 7.7 2.2 8.2 3.3 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Pkinase PF00069.25 CDJ37978.1 - 2.2e-17 63.3 0.1 3.2e-14 52.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ37978.1 - 4.9e-10 39.1 0.0 5.9e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ37978.1 - 0.0057 16.0 0.0 0.0089 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ37978.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LCAT PF02450.15 CDJ37979.1 - 1.3e-37 129.9 0.0 3.8e-37 128.4 0.0 1.7 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Fzo_mitofusin PF04799.13 CDJ37981.1 - 0.18 11.3 2.0 0.31 10.6 2.0 1.3 1 0 0 1 1 1 0 fzo-like conserved region KxDL PF10241.9 CDJ37981.1 - 0.32 11.3 3.0 1.1 9.6 2.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF572 PF04502.13 CDJ37981.1 - 7.9 6.0 11.3 24 4.4 11.3 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF572) GIT_CC PF16559.5 CDJ37982.1 - 0.0021 17.9 2.3 0.0059 16.5 0.3 2.1 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-F_leu_zip PF10473.9 CDJ37982.1 - 0.0079 16.2 6.3 0.0079 16.2 6.3 1.7 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.12 CDJ37982.1 - 0.021 14.7 0.1 0.021 14.7 0.1 2.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CREPT PF16566.5 CDJ37982.1 - 0.36 11.0 7.7 1.2 9.3 2.3 2.0 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Telomere_Sde2_2 PF13297.6 CDJ37984.1 - 6.1e-17 61.0 0.7 1.7e-16 59.6 0.7 1.8 1 0 0 1 1 1 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 CDJ37984.1 - 6.7e-13 48.8 10.0 8.9e-13 48.4 0.1 2.6 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain WD40 PF00400.32 CDJ37985.1 - 1.8e-15 57.0 3.3 4.1e-05 24.2 0.1 4.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ37985.1 - 2.4e-06 27.8 0.0 0.07 13.4 0.0 3.7 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PTH2 PF01981.16 CDJ37986.1 - 1.3e-15 57.7 0.1 1.5e-15 57.5 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 MMR_HSR1 PF01926.23 CDJ37987.1 - 4.3e-17 62.2 0.0 7.9e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ37987.1 - 8.5e-08 31.9 0.0 3.6e-07 29.8 0.1 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ37987.1 - 2e-06 28.0 0.6 0.00012 22.2 0.3 2.3 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.16 CDJ37987.1 - 2.7e-06 26.9 0.0 4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 CDJ37987.1 - 3.7e-05 23.4 0.0 0.92 9.0 0.0 3.2 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ37987.1 - 4.3e-05 23.5 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase PPV_E1_C PF00519.17 CDJ37987.1 - 0.015 14.1 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase ABC_tran PF00005.27 CDJ37987.1 - 0.057 13.9 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 CDJ37987.1 - 0.15 12.3 0.1 0.67 10.2 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CDJ37987.1 - 0.16 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 CDJ37987.1 - 0.27 10.8 0.7 23 4.5 0.1 3.2 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF4229 PF14012.6 CDJ37990.1 - 0.07 13.2 1.5 0.32 11.1 1.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Tweety PF04906.13 CDJ37990.1 - 0.47 9.1 17.0 0.13 10.9 8.0 3.2 3 0 0 3 3 3 0 Tweety ABC_tran PF00005.27 CDJ37991.1 - 9.5e-25 87.7 0.0 2.3e-23 83.2 0.0 2.3 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ37991.1 - 0.00012 22.0 0.0 0.066 13.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ37991.1 - 0.003 17.3 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 CDJ37991.1 - 0.0054 16.2 0.0 0.45 9.9 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CDJ37991.1 - 0.0075 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dicer_dimer PF03368.14 CDJ37991.1 - 0.0076 16.4 0.1 0.89 9.7 0.0 3.1 3 0 0 3 3 3 1 Dicer dimerisation domain AAA_25 PF13481.6 CDJ37991.1 - 0.05 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CDJ37991.1 - 0.081 13.4 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ37991.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Peptidase_C25 PF01364.18 CDJ37991.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 ABC_tran PF00005.27 CDJ37992.1 - 6.8e-14 52.6 0.0 8e-13 49.1 0.0 2.6 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 CDJ37992.1 - 0.00083 19.1 0.1 0.00083 19.1 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ37992.1 - 0.069 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 CDJ37992.1 - 0.095 12.7 1.8 0.19 11.8 0.2 2.1 2 0 0 2 2 2 0 Dynamin family AAA_16 PF13191.6 CDJ37992.1 - 0.2 12.0 0.0 0.2 12.0 0.0 4.8 5 1 0 5 5 5 0 AAA ATPase domain AAA_23 PF13476.6 CDJ37992.1 - 0.36 11.3 4.9 2.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain TFIIA PF03153.13 CDJ37993.1 - 0.0023 18.0 12.0 0.0023 18.0 12.0 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Abhydrolase_1 PF00561.20 CDJ37993.1 - 0.042 13.5 0.0 0.042 13.5 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Coilin_N PF15862.5 CDJ37993.1 - 0.18 11.6 5.9 11 5.9 5.3 2.5 2 1 0 2 2 2 0 Coilin N-terminus DUF2722 PF10846.8 CDJ37993.1 - 2.7 6.8 22.6 0.0087 15.1 11.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SpoIIP PF07454.11 CDJ37993.1 - 3 7.2 7.0 1.3 8.4 2.3 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) S36_mt PF10937.8 CDJ37993.1 - 8 8.1 11.5 32 6.2 5.5 3.1 3 0 0 3 3 3 0 Ribosomal protein S36, mitochondrial Trp_oprn_chp PF09534.10 CDJ37994.1 - 0.0011 18.8 4.9 0.0011 18.8 4.9 4.8 2 1 1 3 3 3 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FAM176 PF14851.6 CDJ37994.1 - 5.7 6.6 14.3 0.86 9.3 4.8 2.4 2 0 0 2 2 2 0 FAM176 family GREB1 PF15782.5 CDJ37994.1 - 6.6 3.7 30.9 8.7 3.3 30.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ribosomal_L12 PF00542.19 CDJ37995.1 - 1.6e-06 28.3 3.0 0.001 19.4 1.2 2.3 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CDJ37995.1 - 0.028 14.1 1.5 0.028 14.1 1.5 4.0 2 2 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain ADK_lid PF05191.14 CDJ37995.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid PUMA PF15826.5 CDJ37995.1 - 0.33 11.1 7.9 0.49 10.6 7.9 1.4 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Spt20 PF12090.8 CDJ37996.1 - 0.56 9.8 7.9 0.54 9.8 7.9 1.1 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ37996.1 - 3.2 8.0 18.2 3.8 7.8 18.2 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Apt1 PF10351.9 CDJ37997.1 - 0.28 10.0 12.0 0.31 9.9 12.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Secretin_N_2 PF07655.13 CDJ37997.1 - 1.2 9.7 22.3 1.5 9.4 6.3 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain NAGLU PF05089.12 CDJ37998.1 - 0.12 11.3 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Phage_HK97_TLTM PF06120.11 CDJ37999.1 - 6e-09 35.5 29.0 3.1 6.9 0.0 10.7 1 1 10 11 11 11 11 Tail length tape measure protein NECFESHC PF16621.5 CDJ37999.1 - 9.4e-07 28.7 46.4 31 4.6 0.1 13.4 12 0 0 12 12 12 11 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 PCYCGC PF13798.6 CDJ37999.1 - 1.7 8.5 34.7 41 4.0 0.0 11.1 12 0 0 12 12 12 0 Protein of unknown function with PCYCGC motif PIG-S PF10510.9 CDJ38000.1 - 1.3e-07 30.9 5.5 0.006 15.5 0.2 4.0 3 1 0 3 3 3 3 Phosphatidylinositol-glycan biosynthesis class S protein HTH_1 PF00126.27 CDJ38000.1 - 0.017 15.1 1.7 0.29 11.1 0.8 3.2 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF2428 PF10350.9 CDJ38000.1 - 0.018 14.3 0.6 0.039 13.2 0.1 1.8 2 0 0 2 2 2 0 Putative death-receptor fusion protein (DUF2428) MFS_1 PF07690.16 CDJ38001.1 - 3.9e-12 45.8 26.2 3.9e-12 45.8 26.2 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily UPF0060 PF02694.15 CDJ38001.1 - 0.01 16.0 2.9 0.01 16.0 2.9 3.8 2 2 1 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family DAD PF02109.16 CDJ38001.1 - 1.7 9.0 10.2 2.7 8.4 7.5 2.8 2 1 0 2 2 2 0 DAD family Cyt_bd_oxida_I PF01654.17 CDJ38002.1 - 4.1 5.9 7.3 8.9 4.8 7.3 1.6 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I Methyltransf_32 PF13679.6 CDJ38003.1 - 0.015 15.3 5.1 0.015 15.3 5.1 4.7 3 2 0 3 3 3 0 Methyltransferase domain RRM_1 PF00076.22 CDJ38004.1 - 3.9e-17 61.8 0.1 1.4e-08 34.4 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ38004.1 - 0.045 13.6 0.0 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif ACDC PF14733.6 CDJ38006.1 - 8.4e-15 54.9 0.0 2.1e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ38006.1 - 8.6e-05 22.7 3.6 0.00023 21.3 3.6 1.8 1 0 0 1 1 1 1 AP2 domain DSPc PF00782.20 CDJ38007.1 - 1.2e-06 28.3 0.1 2.7e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ38007.1 - 0.0026 17.8 0.1 0.0026 17.8 0.1 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Spt20 PF12090.8 CDJ38007.1 - 0.0029 17.3 6.4 0.0029 17.3 6.4 6.6 5 2 1 6 6 6 2 Spt20 family Arm PF00514.23 CDJ38008.1 - 6.5e-12 45.1 0.0 0.00047 20.1 0.0 4.3 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CDJ38008.1 - 0.0003 20.3 0.4 0.011 15.3 0.0 2.8 3 0 0 3 3 3 1 Atypical Arm repeat Atx10homo_assoc PF09759.9 CDJ38008.1 - 0.099 12.7 0.0 10 6.2 0.0 2.9 1 1 2 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Paramyxo_P_V_N PF13825.6 CDJ38009.1 - 0.16 11.4 1.2 0.18 11.2 1.2 1.1 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus CAF1 PF04857.20 CDJ38010.1 - 4.5e-25 88.5 0.1 5.6e-14 52.0 0.0 2.3 1 1 1 2 2 2 2 CAF1 family ribonuclease SUIM_assoc PF16619.5 CDJ38010.1 - 0.0091 16.0 0.1 3.6 7.7 1.7 3.2 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 BAF1_ABF1 PF04684.13 CDJ38011.1 - 0.0028 16.8 4.2 0.0035 16.5 4.2 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor SUIM_assoc PF16619.5 CDJ38011.1 - 0.035 14.2 0.2 0.035 14.2 0.2 3.7 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Myc_N PF01056.18 CDJ38011.1 - 0.45 10.4 10.2 0.76 9.6 10.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Presenilin PF01080.17 CDJ38011.1 - 1.4 7.6 9.8 0.058 12.2 4.5 1.4 2 0 0 2 2 2 0 Presenilin NOA36 PF06524.12 CDJ38011.1 - 2.3 7.5 12.5 3.1 7.0 12.5 1.2 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 CDJ38011.1 - 3.7 7.4 12.4 7.8 6.4 12.4 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Hid1 PF12722.7 CDJ38011.1 - 7.6 4.5 6.6 11 4.1 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_L27A PF00828.19 CDJ38012.1 - 4.5e-23 82.3 0.1 5.8e-23 82.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RskA PF10099.9 CDJ38016.1 - 1.6e-06 28.5 30.0 0.0007 19.9 16.4 2.3 2 0 0 2 2 2 2 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ38016.1 - 0.0012 19.7 0.5 0.0012 19.7 0.5 3.9 4 1 0 4 4 4 1 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ38016.1 - 0.0037 17.3 26.4 0.0037 17.3 26.4 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF4770 PF15994.5 CDJ38016.1 - 0.0037 17.5 2.9 0.0042 17.4 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4770) Spt20 PF12090.8 CDJ38016.1 - 0.01 15.5 21.3 0.01 15.5 21.3 3.0 3 0 0 3 3 3 0 Spt20 family V_ATPase_I PF01496.19 CDJ38016.1 - 0.014 13.3 0.3 0.014 13.3 0.3 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TMEM208_SND2 PF05620.11 CDJ38016.1 - 4.1 7.2 6.8 8.1 6.2 6.8 1.5 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 FHIPEP PF00771.20 CDJ38016.1 - 4.5 5.6 6.1 0.29 9.6 0.7 1.6 2 0 0 2 2 2 0 FHIPEP family Apt1 PF10351.9 CDJ38017.1 - 1.7 7.4 15.6 2.3 7.0 15.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Herpes_UL17 PF04559.12 CDJ38017.1 - 9.2 4.9 17.1 15 4.2 17.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL17 protein E3_UbLigase_R4 PF13764.6 CDJ38018.1 - 0.011 14.0 0.5 0.035 12.3 0.1 1.8 1 1 0 2 2 2 0 E3 ubiquitin-protein ligase UBR4 WD40_alt PF14077.6 CDJ38020.1 - 0.059 13.3 0.1 15 5.6 0.0 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif Roughex PF06020.11 CDJ38020.1 - 0.49 9.4 4.1 0.77 8.8 4.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein CCDC53 PF10152.9 CDJ38020.1 - 1.2 9.5 10.2 0.18 12.2 5.4 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex V_ATPase_I PF01496.19 CDJ38020.1 - 1.9 6.3 3.4 2.6 5.9 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spt20 PF12090.8 CDJ38020.1 - 2.9 7.4 25.5 0.22 11.1 20.4 1.7 2 0 0 2 2 2 0 Spt20 family TPR_19 PF14559.6 CDJ38021.1 - 0.00023 21.6 0.2 0.0054 17.2 0.0 3.9 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ38021.1 - 0.0032 18.2 1.9 0.075 13.9 0.7 5.4 2 2 4 6 6 6 3 Tetratricopeptide repeat DUF1027 PF06265.11 CDJ38021.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) TPR_2 PF07719.17 CDJ38021.1 - 0.15 12.2 0.1 0.15 12.2 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_9 PF00759.19 CDJ38021.1 - 0.5 9.7 4.4 0.42 10.0 1.5 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 9 Spt20 PF12090.8 CDJ38021.1 - 2 8.0 10.0 3 7.4 10.0 1.2 1 0 0 1 1 1 0 Spt20 family ABC_tran PF00005.27 CDJ38022.1 - 1.4e-27 96.8 0.0 1.4e-27 96.8 0.0 4.3 3 1 0 3 3 3 1 ABC transporter ABC_membrane PF00664.23 CDJ38022.1 - 2.1e-20 73.5 0.7 4.5e-20 72.4 0.7 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 CDJ38022.1 - 0.00013 21.9 0.0 0.59 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Activator_LAG-3 PF11498.8 CDJ38022.1 - 0.00074 18.6 47.0 0.00074 18.6 47.0 8.2 8 1 0 8 8 8 1 Transcriptional activator LAG-3 RsgA_GTPase PF03193.16 CDJ38022.1 - 0.013 15.4 0.1 0.013 15.4 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 CDJ38022.1 - 0.024 14.4 0.1 0.07 12.9 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.14 CDJ38022.1 - 0.047 13.6 0.1 0.25 11.3 0.1 2.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 CDJ38022.1 - 0.12 12.7 0.0 0.12 12.7 0.0 4.6 4 1 0 4 4 4 0 AAA domain AAA_18 PF13238.6 CDJ38022.1 - 0.33 11.5 0.0 0.33 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CDJ38022.1 - 0.46 10.6 1.7 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase TFIIA PF03153.13 CDJ38023.1 - 0.49 10.3 4.8 0.59 10.1 4.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIB PF00382.19 CDJ38025.1 - 1.9e-20 72.6 2.0 7.9e-10 38.6 0.1 3.0 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 CDJ38025.1 - 2.9e-14 53.2 5.3 2.9e-14 53.2 5.3 3.1 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 CDJ38025.1 - 2.2e-08 33.5 4.4 4.2e-08 32.6 4.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding AAR2 PF05282.11 CDJ38025.1 - 0.11 11.9 0.6 8.2 5.7 0.2 2.4 2 0 0 2 2 2 0 AAR2 protein DUF4503 PF14951.6 CDJ38025.1 - 0.42 9.0 1.4 0.68 8.3 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) PRA1 PF03208.19 CDJ38026.1 - 3.1e-20 72.2 1.1 4.3e-20 71.8 1.1 1.1 1 0 0 1 1 1 1 PRA1 family protein DctQ PF04290.12 CDJ38026.1 - 0.043 13.7 0.4 0.081 12.8 0.3 1.6 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component YwiC PF14256.6 CDJ38026.1 - 0.31 11.3 6.5 0.47 10.8 1.2 2.3 2 0 0 2 2 2 0 YwiC-like protein KH_1 PF00013.29 CDJ38027.1 - 3.5e-21 74.8 0.0 8.6e-08 31.9 0.0 6.0 6 0 0 6 6 6 4 KH domain KH_2 PF07650.17 CDJ38027.1 - 0.021 14.7 2.9 1.4 8.8 0.0 3.3 3 0 0 3 3 3 0 KH domain BMC PF00936.19 CDJ38027.1 - 0.022 14.7 0.3 0.71 9.9 0.0 3.6 4 0 0 4 4 4 0 BMC domain TolA_bind_tri PF16331.5 CDJ38028.1 - 0.00043 20.3 3.6 0.00043 20.3 3.6 4.5 5 1 0 5 5 5 3 TolA binding protein trimerisation HALZ PF02183.18 CDJ38028.1 - 0.044 14.0 0.3 0.044 14.0 0.3 3.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper Mod_r PF07200.13 CDJ38028.1 - 0.053 13.6 27.8 0.79 9.8 5.7 4.5 4 0 0 4 4 4 0 Modifier of rudimentary (Mod(r)) protein Mce4_CUP1 PF11887.8 CDJ38028.1 - 0.091 12.2 1.3 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF948 PF06103.11 CDJ38028.1 - 0.43 10.9 10.0 5.5 7.3 0.2 4.2 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) C1ORF64 PF15547.6 CDJ38030.1 - 0.12 12.8 1.3 0.14 12.7 0.1 1.6 2 0 0 2 2 2 0 Steroid receptor-associated and regulated protein BCDHK_Adom3 PF10436.9 CDJ38031.1 - 3.5e-13 49.7 0.1 5.4e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase SR-25 PF10500.9 CDJ38031.1 - 0.0043 16.7 10.3 0.0066 16.1 10.3 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ38031.1 - 0.021 14.7 1.0 0.022 14.7 1.0 1.1 1 0 0 1 1 1 0 SPX domain DUF1635 PF07795.11 CDJ38031.1 - 0.038 13.8 7.6 0.059 13.2 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) TFIIA PF03153.13 CDJ38031.1 - 0.069 13.1 2.2 0.071 13.1 2.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kinesin_assoc PF16183.5 CDJ38031.1 - 0.17 12.0 0.8 0.25 11.5 0.6 1.3 1 1 0 1 1 1 0 Kinesin-associated BES1_N PF05687.13 CDJ38031.1 - 1.6 9.1 8.4 2.3 8.6 8.4 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal DUF3138 PF11336.8 CDJ38031.1 - 4.4 5.8 8.6 5.9 5.4 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_60s PF00428.19 CDJ38031.1 - 9.6 6.9 13.9 1.7 9.3 9.9 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4614 PF15391.6 CDJ38032.1 - 0.035 14.1 11.7 0.048 13.7 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Period_C PF12114.8 CDJ38032.1 - 2.1 7.9 24.8 3.1 7.3 24.8 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Apt1 PF10351.9 CDJ38032.1 - 3.6 6.3 6.6 3.5 6.4 6.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain HATPase_c PF02518.26 CDJ38033.1 - 9.7e-14 51.8 0.0 1.4e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDJ38033.1 - 0.0021 17.9 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CASP_C PF08172.12 CDJ38034.1 - 0.0012 18.2 4.2 0.0015 18.0 4.2 1.0 1 0 0 1 1 1 1 CASP C terminal HTH_DeoR PF08220.12 CDJ38034.1 - 0.0038 17.0 0.2 0.0068 16.1 0.2 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain TAF4 PF05236.14 CDJ38034.1 - 0.0046 16.7 6.3 0.0056 16.5 6.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF1645 PF07816.11 CDJ38034.1 - 0.0047 17.5 4.7 0.0057 17.3 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) AF-4 PF05110.13 CDJ38034.1 - 0.0067 14.6 8.2 0.0084 14.3 8.2 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein FCP1_C PF09309.10 CDJ38034.1 - 0.063 13.1 6.8 0.077 12.9 6.8 1.0 1 0 0 1 1 1 0 FCP1, C-terminal BAF1_ABF1 PF04684.13 CDJ38034.1 - 0.065 12.3 2.4 0.076 12.1 2.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CDJ38034.1 - 0.069 13.1 6.1 0.076 13.0 6.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ38034.1 - 0.087 11.8 5.6 0.12 11.4 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4667 PF15700.5 CDJ38034.1 - 0.092 12.8 5.6 0.12 12.5 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Spt20 PF12090.8 CDJ38034.1 - 0.13 11.9 8.5 0.15 11.7 8.5 1.1 1 0 0 1 1 1 0 Spt20 family PAP1 PF08601.10 CDJ38034.1 - 0.53 10.0 10.0 0.65 9.7 10.0 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 MCU PF04678.13 CDJ38034.1 - 1.6 8.8 4.2 2 8.5 4.2 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF3138 PF11336.8 CDJ38034.1 - 2 6.9 10.8 2.3 6.8 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Chromo PF00385.24 CDJ38035.1 - 1.1e-07 31.6 0.1 2.1e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCCH PF00642.24 CDJ38036.1 - 4.9e-08 32.7 16.2 8.9e-05 22.3 1.5 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ38036.1 - 0.0031 17.3 2.9 0.0031 17.3 2.9 4.1 4 1 0 4 4 4 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CDJ38036.1 - 0.011 15.9 16.0 0.014 15.6 2.6 3.9 3 1 1 4 4 4 0 Zinc-finger containing family Torus PF16131.5 CDJ38036.1 - 0.039 14.7 0.1 0.039 14.7 0.1 5.3 4 2 1 5 5 5 0 Torus domain zf_CCCH_4 PF18345.1 CDJ38036.1 - 0.91 9.7 15.9 2.2 8.4 3.9 4.5 3 2 0 3 3 3 0 Zinc finger domain Ndc1_Nup PF09531.10 CDJ38036.1 - 4.7 5.8 21.4 0.81 8.3 17.9 1.6 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup zf-RING_2 PF13639.6 CDJ38037.1 - 1.3e-10 41.4 3.0 2.4e-10 40.6 3.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CDJ38037.1 - 3.9e-08 33.5 2.5 1.1e-07 32.0 2.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ38037.1 - 4.5e-08 32.8 1.9 8.6e-08 31.9 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ38037.1 - 1.8e-06 27.7 2.6 3.5e-06 26.7 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ38037.1 - 1.3e-05 25.1 2.2 2.6e-05 24.1 2.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ38037.1 - 1.7e-05 24.7 2.4 2.4e-05 24.3 0.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ38037.1 - 2.2e-05 24.2 4.3 4e-05 23.4 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ38037.1 - 9.1e-05 22.1 3.1 9.1e-05 22.1 3.1 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 CDJ38037.1 - 0.0002 21.3 2.2 0.0002 21.3 2.2 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CDJ38037.1 - 0.0013 18.3 3.7 0.0026 17.3 3.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CDJ38037.1 - 0.0019 18.0 6.4 0.0038 17.1 6.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CDJ38037.1 - 0.031 14.4 3.6 0.11 12.7 3.6 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 CDJ38037.1 - 0.034 14.3 2.8 0.092 12.9 2.8 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 CDJ38037.1 - 0.12 12.5 3.6 0.32 11.1 3.6 1.8 1 0 0 1 1 1 0 RING-variant domain Endomucin PF07010.12 CDJ38038.1 - 1.3 9.0 10.8 8.7 6.2 10.9 1.9 1 1 0 1 1 1 0 Endomucin SART-1 PF03343.13 CDJ38039.1 - 0.072 11.6 0.8 0.15 10.6 0.8 1.4 1 0 0 1 1 1 0 SART-1 family BAMBI PF06211.12 CDJ38040.1 - 0.2 11.9 0.1 0.2 11.9 0.1 2.8 3 0 0 3 3 3 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Amastin PF07344.11 CDJ38040.1 - 4.1 7.2 33.8 0.22 11.4 12.0 3.0 2 2 1 3 3 3 0 Amastin surface glycoprotein Ribosomal_L7Ae PF01248.26 CDJ38041.1 - 5.5e-28 96.6 0.5 7e-28 96.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.12 CDJ38041.1 - 0.0024 18.1 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding eIF-5_eIF-2B PF01873.17 CDJ38042.1 - 4.9e-10 39.3 0.0 1.1e-09 38.1 0.0 1.6 2 0 0 2 2 2 1 Domain found in IF2B/IF5 ETAA1 PF15350.6 CDJ38042.1 - 0.12 10.7 0.0 0.14 10.4 0.0 1.2 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue Ribosomal_L6e PF01159.19 CDJ38045.1 - 3.1e-32 111.4 0.7 4.6e-32 110.9 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Kelch_3 PF13415.6 CDJ38046.1 - 1.1e-21 76.6 0.4 1.1e-06 28.8 0.1 4.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 CDJ38046.1 - 1.5e-16 60.1 2.1 8.8e-05 22.4 0.0 4.6 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ38046.1 - 8.6e-12 44.8 1.8 0.018 15.0 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 CDJ38046.1 - 1.7e-10 40.8 0.1 0.21 11.9 0.1 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CDJ38046.1 - 5.2e-06 26.2 4.0 0.24 11.4 1.1 4.6 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 CDJ38046.1 - 0.0017 17.9 0.5 4.7 6.9 0.1 3.9 3 0 0 3 3 3 1 Kelch motif DUF755 PF05501.11 CDJ38046.1 - 0.16 12.2 14.4 2.5 8.4 14.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF755) GRIM-19 PF06212.12 CDJ38046.1 - 0.29 11.1 0.9 0.57 10.1 0.9 1.4 1 0 0 1 1 1 0 GRIM-19 protein Spc7 PF08317.11 CDJ38046.1 - 1 8.2 8.4 3 6.6 8.1 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein BshC PF10079.9 CDJ38046.1 - 2.2 6.9 6.2 3.2 6.4 6.2 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Prefoldin PF02996.17 CDJ38046.1 - 5.5 6.9 10.2 2.8 7.9 1.5 2.5 2 0 0 2 2 2 0 Prefoldin subunit FlxA PF14282.6 CDJ38046.1 - 8.1 6.5 21.2 2.8 8.0 6.7 2.6 2 0 0 2 2 2 0 FlxA-like protein Ribosomal_L28 PF00830.19 CDJ38048.1 - 1.7e-11 44.2 1.3 1.3e-10 41.3 1.8 2.3 2 0 0 2 2 2 1 Ribosomal L28 family SUIM_assoc PF16619.5 CDJ38048.1 - 6.3 6.9 30.8 0.46 10.6 7.6 4.4 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 CDJ38051.1 - 2.2e-33 115.8 0.0 4.1e-33 114.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ38051.1 - 1.9e-29 102.7 0.0 4.2e-28 98.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ38051.1 - 0.00042 19.2 0.0 0.00056 18.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ38051.1 - 0.00083 18.8 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CDJ38051.1 - 0.0059 16.6 0.0 0.017 15.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family SUIM_assoc PF16619.5 CDJ38051.1 - 0.029 14.4 2.1 0.046 13.8 2.1 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TrmO_C PF18389.1 CDJ38051.1 - 0.13 12.3 4.9 0.62 10.2 0.0 2.2 2 0 0 2 2 2 0 TrmO C-terminal domain PALP PF00291.25 CDJ38055.1 - 3.7e-14 52.8 0.0 1.4e-07 31.3 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme TAF1D PF15333.6 CDJ38055.1 - 0.08 12.7 0.3 0.11 12.3 0.3 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D CTNNBL PF08216.11 CDJ38056.1 - 1.7e-30 105.3 0.6 3.7e-30 104.2 0.6 1.6 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear FTCD_C PF04961.12 CDJ38056.1 - 0.0069 16.2 3.1 0.015 15.1 3.1 1.5 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase DUF2312 PF10073.9 CDJ38056.1 - 0.023 14.3 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Arm PF00514.23 CDJ38056.1 - 0.1 12.7 0.1 0.71 10.0 0.0 2.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat FKBP_N PF01346.18 CDJ38057.1 - 0.017 16.0 0.9 0.017 16.0 0.9 2.3 1 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FliG_N PF14842.6 CDJ38057.1 - 0.031 14.8 8.5 0.29 11.7 2.0 3.0 2 1 0 2 2 2 0 FliG N-terminal domain SCO1-SenC PF02630.14 CDJ38057.1 - 0.067 13.1 0.2 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 SCO1/SenC NAC PF01849.18 CDJ38058.1 - 7.3e-07 29.1 1.3 1.4e-06 28.1 1.3 1.4 1 0 0 1 1 1 1 NAC domain YL1 PF05764.13 CDJ38058.1 - 0.61 10.1 14.0 1 9.5 14.0 1.4 1 1 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 CDJ38058.1 - 0.72 8.1 5.7 0.73 8.1 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PGK PF00162.19 CDJ38059.1 - 9.8e-146 485.5 1.1 1.1e-145 485.4 1.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF1279 PF06916.13 CDJ38060.1 - 1.1e-06 29.1 0.1 4.6e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) UPF0167 PF03691.14 CDJ38060.1 - 2.3 8.0 4.5 0.53 10.1 0.6 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) DHQ_synthase PF01761.20 CDJ38061.1 - 4.2e-70 235.9 13.5 1.4e-33 116.2 0.0 4.4 2 1 2 4 4 4 3 3-dehydroquinate synthase EPSP_synthase PF00275.20 CDJ38061.1 - 4.6e-10 38.8 1.5 0.0026 16.5 0.5 4.2 3 2 1 4 4 4 3 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Macoilin PF09726.9 CDJ38061.1 - 0.00022 20.0 0.8 0.00022 20.0 0.8 6.2 4 2 2 6 6 6 1 Macoilin family Velvet PF11754.8 CDJ38061.1 - 0.001 19.1 0.9 0.001 19.1 0.9 7.0 4 3 0 4 4 4 1 Velvet factor PNISR PF15996.5 CDJ38061.1 - 0.01 16.2 1.5 0.01 16.2 1.5 7.7 7 1 0 7 7 7 0 Arginine/serine-rich protein PNISR Otopetrin PF03189.13 CDJ38061.1 - 0.49 9.2 0.0 0.49 9.2 0.0 3.8 3 2 0 3 3 3 0 Otopetrin NAC PF01849.18 CDJ38062.1 - 8.6e-13 48.1 0.4 2e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 NAC domain SUIM_assoc PF16619.5 CDJ38062.1 - 0.0011 18.9 5.2 0.0011 18.9 5.2 2.0 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Flagellin_N PF00669.20 CDJ38062.1 - 0.0085 16.2 1.8 0.0085 16.2 1.8 1.9 1 1 1 2 2 2 1 Bacterial flagellin N-terminal helical region Succ_CoA_lig PF13607.6 CDJ38062.1 - 0.022 14.5 0.3 0.057 13.2 0.3 1.6 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain MRP-S31 PF15433.6 CDJ38062.1 - 0.24 11.0 8.0 0.044 13.5 1.8 2.0 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 YbjQ_1 PF01906.17 CDJ38062.1 - 0.36 11.5 3.3 0.62 10.7 1.9 2.0 2 1 0 2 2 2 0 Putative heavy-metal-binding DUF2477 PF10631.9 CDJ38062.1 - 0.66 10.6 5.5 1.3 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) Nitrate_red_del PF02613.15 CDJ38062.1 - 1.4 9.0 7.4 4.8 7.2 7.4 2.0 1 1 0 1 1 1 0 Nitrate reductase delta subunit LPP20 PF02169.16 CDJ38062.1 - 2.4 8.6 8.8 0.9 9.9 2.2 2.6 2 1 0 2 2 2 0 LPP20 lipoprotein Spt5_N PF11942.8 CDJ38063.1 - 4.5e-05 24.4 6.6 4.5e-05 24.4 6.6 2.2 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Exostosin PF03016.15 CDJ38063.1 - 0.0063 15.8 0.2 0.0063 15.8 0.2 1.8 2 0 0 2 2 2 1 Exostosin family SR-25 PF10500.9 CDJ38063.1 - 0.0077 15.9 28.3 0.0077 15.9 28.3 2.0 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein SART-1 PF03343.13 CDJ38063.1 - 0.36 9.3 32.4 0.46 9.0 32.4 1.0 1 0 0 1 1 1 0 SART-1 family PAS PF00989.25 CDJ38063.1 - 0.89 9.6 4.3 12 5.9 0.3 2.1 2 0 0 2 2 2 0 PAS fold Spt20 PF12090.8 CDJ38063.1 - 3 7.4 32.8 0.4 10.2 6.8 2.1 2 0 0 2 2 2 0 Spt20 family NAM-associated PF14303.6 CDJ38063.1 - 3 8.5 30.0 3.8 8.2 30.0 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF1764 PF08576.10 CDJ38063.1 - 3.2 8.7 23.7 2.9 8.8 1.9 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) SOBP PF15279.6 CDJ38063.1 - 7.5 7.1 17.4 8.7 6.8 17.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 CDJ38065.1 - 0.0007 18.4 3.4 0.00079 18.2 3.4 1.1 1 0 0 1 1 1 1 Hamartin protein DUF4834 PF16118.5 CDJ38065.1 - 0.17 12.8 3.0 0.36 11.8 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Sec16 PF12932.7 CDJ38065.1 - 2.8 8.5 9.9 10 6.7 2.0 3.0 2 1 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region AIM3 PF17096.5 CDJ38065.1 - 4.1 8.4 6.4 0.51 11.3 0.7 2.2 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 AAA_23 PF13476.6 CDJ38067.1 - 9 6.7 15.5 1.7 9.1 2.9 3.3 3 0 0 3 3 3 0 AAA domain Cyclin PF08613.11 CDJ38072.1 - 7.9e-31 107.6 6.2 8.6e-31 107.5 0.0 2.8 3 1 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 CDJ38072.1 - 1e-06 28.5 0.1 1e-06 28.5 0.1 3.0 3 1 0 3 3 3 1 Cyclin, N-terminal domain GHMP_kinases_N PF00288.26 CDJ38072.1 - 0.00016 21.8 0.2 0.00046 20.4 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain CRR7 PF12095.8 CDJ38072.1 - 0.021 15.2 8.0 0.021 15.2 8.0 2.7 4 0 0 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF3471 PF11954.8 CDJ38072.1 - 0.098 13.1 0.5 3 8.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) FixG_C PF11614.8 CDJ38073.1 - 0.029 14.6 0.2 0.044 14.0 0.2 1.3 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase SNF2_N PF00176.23 CDJ38075.1 - 9e-16 57.5 0.0 1.2e-12 47.2 0.0 2.7 3 0 0 3 3 3 2 SNF2 family N-terminal domain zf-C4_Topoisom PF01396.19 CDJ38075.1 - 1.6e-06 27.8 4.5 1.6e-06 27.8 4.5 2.5 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger Helicase_C PF00271.31 CDJ38075.1 - 0.00033 21.0 0.0 0.00089 19.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HNH PF01844.23 CDJ38075.1 - 0.00089 19.4 0.0 0.003 17.7 0.0 1.9 1 0 0 1 1 1 1 HNH endonuclease ResIII PF04851.15 CDJ38075.1 - 0.0035 17.4 0.0 0.0091 16.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ38075.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF1068 PF06364.12 CDJ38075.1 - 2.7 7.9 8.7 0.18 11.7 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) RNA_polI_A34 PF08208.11 CDJ38076.1 - 0.41 10.7 24.0 0.57 10.2 24.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2796 PF10986.8 CDJ38076.1 - 1.1 9.2 18.7 1.5 8.7 18.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Glyco_tran_28_C PF04101.16 CDJ38077.1 - 1.8e-16 60.6 0.0 2.6e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain WD40 PF00400.32 CDJ38078.1 - 0.024 15.5 5.2 0.083 13.8 0.6 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat CPSase_L_D2 PF02786.17 CDJ38079.1 - 9e-110 365.1 0.0 1.2e-78 263.4 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CDJ38079.1 - 3.7e-43 146.4 0.0 8.2e-43 145.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CDJ38079.1 - 2.6e-41 141.5 0.0 6.5e-41 140.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 CDJ38079.1 - 6.1e-38 129.9 1.6 1e-37 129.2 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 CDJ38079.1 - 1.6e-16 60.4 0.0 2.3e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CDJ38079.1 - 1.1e-15 57.7 0.0 3e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CDJ38079.1 - 4.3e-14 52.4 0.0 1.5e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 CDJ38079.1 - 1.8e-11 44.1 0.0 1.5e-10 41.1 0.0 2.7 2 0 0 2 2 2 1 MGS-like domain Peptidase_C26 PF07722.13 CDJ38079.1 - 2.1e-05 24.4 0.1 0.001 18.8 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 CDJ38079.1 - 0.00027 21.0 0.1 0.27 11.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 CDJ38079.1 - 0.0011 18.5 0.1 0.0031 17.0 0.1 1.8 1 0 0 1 1 1 1 ATP-grasp domain DJ-1_PfpI PF01965.24 CDJ38079.1 - 0.037 13.8 0.1 0.29 10.9 0.0 2.4 3 0 0 3 3 3 0 DJ-1/PfpI family Nitro_FeMo-Co PF02579.17 CDJ38079.1 - 0.3 11.4 1.9 6.5 7.2 0.0 3.4 4 0 0 4 4 3 0 Dinitrogenase iron-molybdenum cofactor MFS_1 PF07690.16 CDJ38081.1 - 1e-29 103.6 29.3 9.9e-23 80.6 2.9 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily BT1 PF03092.16 CDJ38081.1 - 0.99 7.5 18.9 0.23 9.6 4.2 3.2 4 0 0 4 4 4 0 BT1 family WD40 PF00400.32 CDJ38082.1 - 1.2e-28 98.8 22.9 0.00012 22.8 0.1 12.0 11 1 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ38082.1 - 1.7e-12 47.4 0.6 2 8.8 0.0 8.4 6 1 2 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CDJ38082.1 - 3.1e-08 33.9 1.6 7e-08 32.7 1.6 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family SR-25 PF10500.9 CDJ38082.1 - 0.073 12.7 15.2 0.39 10.3 5.4 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein CTU2 PF10288.9 CDJ38082.1 - 6.4 7.1 12.4 38 4.6 2.9 3.8 4 0 0 4 4 4 0 Cytoplasmic tRNA 2-thiolation protein 2 FAM176 PF14851.6 CDJ38082.1 - 7 6.3 7.0 3.5 7.3 0.6 2.7 3 0 0 3 3 3 0 FAM176 family RTC PF01137.21 CDJ38083.1 - 1.2e-28 99.9 0.3 1.6e-28 99.5 0.3 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CDJ38083.1 - 3.8e-12 46.6 9.2 1.1e-11 45.2 4.5 3.1 2 1 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Thioredoxin_8 PF13905.6 CDJ38084.1 - 7.7e-24 83.9 0.0 1.2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CDJ38084.1 - 0.043 13.7 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family SCO1-SenC PF02630.14 CDJ38084.1 - 0.21 11.5 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC PI3_PI4_kinase PF00454.27 CDJ38085.1 - 4.4e-31 108.6 0.2 1.9e-29 103.2 0.2 2.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CDJ38085.1 - 1.6e-15 57.0 0.1 4.8e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CSN8_PSD8_EIF3K PF10075.9 CDJ38085.1 - 0.035 14.1 0.1 0.09 12.7 0.1 1.6 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Lactamase_B_2 PF12706.7 CDJ38086.1 - 5e-25 88.2 0.1 6.6e-16 58.4 0.0 2.6 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDJ38086.1 - 4.1e-07 30.0 0.0 1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ38086.1 - 0.0015 18.6 4.3 0.0015 18.6 0.2 2.7 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Dabb PF07876.12 CDJ38087.1 - 4.4e-18 65.7 0.3 5e-18 65.5 0.3 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DZR PF12773.7 CDJ38090.1 - 0.26 11.3 7.2 0.086 12.9 1.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 CDJ38090.1 - 0.32 10.4 4.2 0.19 11.2 1.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain PHD PF00628.29 CDJ38090.1 - 0.53 10.2 9.5 1.3 9.0 2.0 2.5 2 0 0 2 2 2 0 PHD-finger HypA PF01155.19 CDJ38090.1 - 0.74 9.9 6.4 0.15 12.1 0.5 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_11 PF17123.5 CDJ38090.1 - 2.4 8.0 4.5 1.4 8.7 2.0 2.0 2 0 0 2 2 2 0 RING-like zinc finger Prok-RING_1 PF14446.6 CDJ38090.1 - 7.1 6.6 8.6 0.92 9.5 1.0 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C6H2 PF15801.5 CDJ38090.1 - 9.3 6.7 8.2 23 5.4 0.6 2.7 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding PHD PF00628.29 CDJ38091.1 - 8.8e-15 54.3 24.0 3.4e-12 46.1 11.3 4.5 2 1 2 4 4 4 2 PHD-finger PHD_2 PF13831.6 CDJ38091.1 - 4.8e-06 26.0 11.9 0.00021 20.8 0.6 5.0 6 0 0 6 6 6 2 PHD-finger C1_1 PF00130.22 CDJ38091.1 - 0.00017 21.4 29.5 0.0055 16.6 4.8 4.6 3 2 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 CDJ38091.1 - 0.015 15.7 31.3 17 5.9 5.8 4.4 2 2 1 3 3 3 0 Ring finger domain zf-CCHC_2 PF13696.6 CDJ38091.1 - 0.28 11.0 0.3 0.28 11.0 0.3 3.6 4 0 0 4 4 4 0 Zinc knuckle Trm112p PF03966.16 CDJ38091.1 - 0.67 10.6 4.9 0.35 11.5 0.9 2.5 2 1 0 2 2 2 0 Trm112p-like protein zf-PHD-like PF15446.6 CDJ38091.1 - 0.76 9.4 22.6 0.76 9.4 1.9 3.3 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain FYVE_2 PF02318.16 CDJ38091.1 - 0.84 9.9 34.9 0.065 13.5 6.5 3.7 1 1 3 4 4 4 0 FYVE-type zinc finger CASP_C PF08172.12 CDJ38092.1 - 2.3e-14 53.3 4.8 4.1e-09 36.2 0.1 5.9 3 1 3 6 6 6 3 CASP C terminal PNTB PF02233.16 CDJ38093.1 - 3.4e-29 102.1 0.0 5.2e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 CDJ38093.1 - 3.9e-23 81.9 0.0 5.1e-22 78.2 0.0 2.3 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 CDJ38093.1 - 0.0043 17.3 0.0 0.06 13.7 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain FAD_oxidored PF12831.7 CDJ38093.1 - 0.014 14.7 1.3 0.014 14.7 1.3 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 CDJ38093.1 - 0.2 10.7 1.7 0.38 9.8 1.7 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Presenilin PF01080.17 CDJ38093.1 - 0.56 8.9 4.7 0.78 8.4 4.7 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CDJ38093.1 - 1.9 9.1 10.3 3.3 8.3 10.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ38093.1 - 2.8 7.9 17.6 4 7.3 17.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ38093.1 - 9.1 5.8 21.6 14 5.2 21.6 1.2 1 0 0 1 1 1 0 Spt20 family DNA_topoisoIV PF00521.20 CDJ38094.1 - 1.3e-85 287.9 0.0 5e-49 167.4 0.0 3.2 3 0 0 3 3 3 3 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 CDJ38094.1 - 1.8e-29 100.9 7.1 7.9e-09 34.9 0.0 5.4 5 0 0 5 5 5 4 DNA gyrase C-terminal domain, beta-propeller DUF4559 PF15112.6 CDJ38094.1 - 0.84 9.3 4.3 1.4 8.6 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) FliT PF05400.13 CDJ38094.1 - 1.8 9.4 17.7 0.047 14.5 8.4 2.7 1 1 1 2 2 2 0 Flagellar protein FliT NFACT-R_1 PF05670.13 CDJ38095.1 - 1.2e-09 38.7 0.0 2.6e-08 34.5 0.0 2.4 1 1 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 CDJ38095.1 - 0.0075 16.4 0.0 4.1 7.7 0.0 2.8 2 1 0 3 3 3 2 NFACT protein RNA binding domain PIP5K PF01504.18 CDJ38096.1 - 2e-24 86.3 0.0 1.7e-16 60.3 0.0 3.1 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.21 CDJ38096.1 - 1.1e-14 54.3 11.7 1.1e-14 54.3 11.7 2.8 3 0 0 3 3 3 1 FYVE zinc finger Cpn60_TCP1 PF00118.24 CDJ38096.1 - 0.00053 18.7 0.0 0.0014 17.3 0.0 1.6 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family Vwaint PF14624.6 CDJ38096.1 - 0.0054 16.8 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 VWA / Hh protein intein-like Nop PF01798.18 CDJ38097.1 - 2e-80 269.6 0.2 3.6e-80 268.7 0.2 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CDJ38097.1 - 4e-16 59.2 1.0 1e-15 57.9 1.0 1.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF3138 PF11336.8 CDJ38097.1 - 0.083 11.5 1.6 0.14 10.7 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ATP-cone PF03477.16 CDJ38097.1 - 0.13 12.8 1.4 9.3 6.9 0.4 3.0 2 1 1 3 3 3 0 ATP cone domain TPR_2 PF07719.17 CDJ38098.1 - 3.9e-09 35.9 12.3 8.8e-05 22.3 0.7 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ38098.1 - 1.4e-06 27.8 4.7 0.006 16.4 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ38098.1 - 9.9e-06 25.1 3.8 1.7 8.4 0.0 4.1 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 CDJ38098.1 - 3e-05 23.9 6.4 0.15 12.4 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ38098.1 - 0.00028 21.5 3.8 0.00028 21.5 3.8 8.3 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ38098.1 - 0.0038 17.8 0.9 0.0038 17.8 0.9 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ38098.1 - 0.035 14.3 0.4 0.23 11.7 0.4 2.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 CDJ38098.1 - 0.039 14.0 5.6 0.049 13.7 0.3 3.4 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 CDJ38098.1 - 0.53 10.5 10.5 0.032 14.4 2.6 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ38098.1 - 3.1 8.4 9.2 1 9.9 0.3 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat RRM_1 PF00076.22 CDJ38099.1 - 1.4e-31 108.2 0.2 2.2e-14 53.0 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ38099.1 - 2.7e-05 24.2 0.0 0.037 14.1 0.0 2.9 2 2 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 CDJ38099.1 - 0.053 13.2 0.2 0.69 9.6 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain SUIM_assoc PF16619.5 CDJ38100.1 - 4.4 7.5 7.0 0.38 10.8 0.9 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4653 PF15546.6 CDJ38101.1 - 0.28 10.8 4.3 0.47 10.0 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF4653 PF15546.6 CDJ38102.1 - 0.57 9.8 5.4 0.87 9.2 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF4653 PF15546.6 CDJ38103.1 - 0.47 10.0 5.4 0.87 9.2 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF4653 PF15546.6 CDJ38104.1 - 0.44 10.1 5.4 0.86 9.2 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF4653 PF15546.6 CDJ38106.1 - 0.28 10.8 4.1 0.52 9.9 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Helicase_C PF00271.31 CDJ38108.1 - 3.1e-26 91.9 0.0 7.1e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ38108.1 - 1.9e-15 57.1 0.1 7.4e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase SUIM_assoc PF16619.5 CDJ38108.1 - 0.022 14.8 4.5 0.067 13.3 4.5 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Cluap1 PF10234.9 CDJ38109.1 - 3.7e-10 39.7 15.5 9.4e-10 38.3 14.3 2.1 1 1 0 1 1 1 1 Clusterin-associated protein-1 FlaC_arch PF05377.11 CDJ38109.1 - 0.0048 17.3 2.1 0.051 14.0 0.8 2.8 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) HALZ PF02183.18 CDJ38109.1 - 0.051 13.8 1.3 0.051 13.8 1.3 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper TMCO5 PF14992.6 CDJ38109.1 - 0.13 11.8 11.3 0.092 12.3 9.3 1.7 1 1 0 1 1 1 0 TMCO5 family BST2 PF16716.5 CDJ38109.1 - 0.3 11.7 15.5 5.3 7.7 3.4 3.5 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 FAM76 PF16046.5 CDJ38109.1 - 8.5 5.6 11.9 2.4 7.4 8.6 1.7 1 1 1 2 2 2 0 FAM76 protein Peptidase_C15 PF01470.17 CDJ38110.1 - 3.2e-16 60.1 0.0 1.6e-11 44.8 0.0 2.1 2 0 0 2 2 2 2 Pyroglutamyl peptidase SLATT_1 PF18181.1 CDJ38112.1 - 0.047 13.6 2.2 0.17 11.8 1.0 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 RNA_pol PF00940.19 CDJ38113.1 - 3.5e-134 447.7 0.0 9e-134 446.4 0.0 1.8 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CDJ38113.1 - 3.5e-15 56.2 10.9 6.8e-09 35.6 0.2 6.5 5 2 1 6 6 6 3 DNA-directed RNA polymerase N-terminal YcgR PF07317.12 CDJ38113.1 - 0.0069 16.2 0.2 0.026 14.4 0.2 2.1 1 0 0 1 1 1 1 Flagellar regulator YcgR YgbB PF02542.16 CDJ38114.1 - 1.4e-46 158.6 1.0 5.2e-45 153.5 1.0 2.3 1 1 0 1 1 1 1 YgbB family ABC2_membrane_2 PF12679.7 CDJ38115.1 - 1.8 7.8 3.6 0.37 10.0 0.2 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein eIF-1a PF01176.19 CDJ38116.1 - 4.7e-06 26.3 0.1 7.6e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_60s PF00428.19 CDJ38116.1 - 0.0031 18.1 1.8 0.0031 18.1 1.8 3.5 4 0 0 4 4 4 1 60s Acidic ribosomal protein RskA PF10099.9 CDJ38116.1 - 0.046 14.0 1.4 0.046 14.0 1.4 2.5 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Dehydrin PF00257.19 CDJ38116.1 - 0.18 12.4 0.3 0.18 12.4 0.3 2.8 3 0 0 3 3 3 0 Dehydrin Fasciclin PF02469.22 CDJ38117.1 - 1.5e-09 38.1 0.0 2.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain Secretin_N_2 PF07655.13 CDJ38117.1 - 0.44 11.1 25.1 0.3 11.6 7.9 3.2 3 0 0 3 3 3 0 Secretin N-terminal domain Mito_fiss_reg PF05308.11 CDJ38117.1 - 5.3 7.1 7.7 13 5.8 7.7 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator Coiled PF05710.12 CDJ38117.1 - 6.6 7.6 30.2 0.2 12.5 9.4 3.3 3 0 0 3 3 3 0 Coiled coil Pan3_PK PF18101.1 CDJ38119.1 - 7.2e-37 126.4 0.0 2.3e-36 124.8 0.0 2.0 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 CDJ38119.1 - 0.00085 18.8 0.0 0.00085 18.8 0.0 3.2 3 0 0 3 3 3 1 Protein kinase domain RskA PF10099.9 CDJ38119.1 - 0.0052 17.1 3.5 0.0052 17.1 3.5 7.6 3 1 1 5 5 5 2 Anti-sigma-K factor rskA DUF4395 PF14340.6 CDJ38119.1 - 8.6 6.7 9.5 0.67 10.3 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) PepSY_TM_like_2 PF16357.5 CDJ38120.1 - 0.36 10.8 9.5 0.042 13.8 3.4 2.2 2 0 0 2 2 2 0 Putative PepSY_TM-like SLC12 PF03522.15 CDJ38120.1 - 0.8 8.7 10.6 1.3 8.0 3.1 2.3 2 0 0 2 2 2 0 Solute carrier family 12 Fucose_iso_N2 PF07882.12 CDJ38121.1 - 0.31 10.6 1.1 0.59 9.7 1.1 1.4 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain DUF2722 PF10846.8 CDJ38122.1 - 0.00033 19.7 3.2 0.00033 19.7 3.2 6.6 5 2 1 6 6 6 1 Protein of unknown function (DUF2722) DUF755 PF05501.11 CDJ38122.1 - 0.0023 18.2 11.1 0.0023 18.2 11.1 6.6 4 1 1 5 5 5 1 Domain of unknown function (DUF755) LANC_like PF05147.13 CDJ38123.1 - 4.4e-31 107.7 1.0 1.3e-08 33.8 0.0 5.2 5 0 0 5 5 5 5 Lanthionine synthetase C-like protein Glyco_hydro_9 PF00759.19 CDJ38123.1 - 0.038 13.4 7.2 0.027 13.9 1.6 2.5 2 1 0 2 2 2 0 Glycosyl hydrolase family 9 Band_3_cyto PF07565.13 CDJ38123.1 - 0.44 10.3 2.3 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain EF-hand_6 PF13405.6 CDJ38124.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Prophage_tail PF06605.11 CDJ38125.1 - 0.0086 15.3 3.5 0.013 14.7 3.5 1.2 1 0 0 1 1 1 1 Prophage endopeptidase tail SHMT PF00464.19 CDJ38127.1 - 2.9e-147 490.5 0.0 4e-112 374.7 0.0 2.0 1 1 1 2 2 2 2 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 CDJ38127.1 - 0.05 12.9 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family PI3_PI4_kinase PF00454.27 CDJ38128.1 - 3e-33 115.7 0.0 5.3e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase AAA_32 PF13654.6 CDJ38129.1 - 0.0076 15.1 0.2 0.013 14.3 0.2 1.3 1 0 0 1 1 1 1 AAA domain RGS-like PF09128.11 CDJ38129.1 - 0.093 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain baeRF_family3 PF18845.1 CDJ38129.1 - 0.78 10.0 2.6 19 5.5 0.1 3.4 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 3 RPN1_RPN2_N PF17781.1 CDJ38130.1 - 6.3e-112 374.0 0.1 9.7e-112 373.3 0.1 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CDJ38130.1 - 7.6e-27 93.1 0.1 1.7e-26 92.0 0.1 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CDJ38130.1 - 6.3e-11 42.1 34.7 0.00027 21.2 0.2 8.7 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CDJ38130.1 - 0.0085 16.5 4.6 0.12 12.7 0.0 4.2 3 1 1 4 4 4 1 HEAT repeats DUF3682 PF12446.8 CDJ38130.1 - 7.2 7.1 19.6 0.27 11.7 11.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) PCI PF01399.27 CDJ38131.1 - 6e-12 46.0 0.2 1.4e-11 44.8 0.2 1.6 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 CDJ38131.1 - 0.038 14.1 0.1 0.72 10.1 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF736 PF05284.12 CDJ38133.1 - 0.12 12.3 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF736) YjbT PF17089.5 CDJ38134.1 - 0.087 12.8 0.1 0.48 10.5 0.1 2.3 1 0 0 1 1 1 0 Uncharacterised protein family HEAT PF02985.22 CDJ38134.1 - 8.7 6.9 12.2 6.2 7.4 0.2 5.1 5 0 0 5 5 5 0 HEAT repeat zf-CCCH_2 PF14608.6 CDJ38135.1 - 4.8e-10 39.5 35.5 0.00019 21.8 5.9 3.3 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CDJ38135.1 - 1.7e-06 27.7 15.9 0.02 14.7 0.2 4.0 4 0 0 4 4 4 3 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ38135.1 - 0.0041 17.0 0.9 0.0041 17.0 0.9 4.0 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ38135.1 - 0.0088 16.1 20.9 0.18 11.9 0.6 4.0 3 1 1 4 4 4 3 Zinc finger domain PWI PF01480.17 CDJ38135.1 - 0.013 15.8 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 PWI domain Nab2p_Zf1 PF18260.1 CDJ38135.1 - 0.02 14.8 2.4 0.02 14.8 2.4 2.6 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 zf-C3H1 PF10650.9 CDJ38135.1 - 0.077 12.7 2.2 0.27 11.0 2.2 1.9 1 0 0 1 1 1 0 Putative zinc-finger domain DEDD_Tnp_IS110 PF01548.17 CDJ38135.1 - 0.088 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Transposase ATG101 PF07855.12 CDJ38136.1 - 1.1e-08 35.2 0.0 0.034 14.1 0.0 3.2 3 0 0 3 3 3 3 Autophagy-related protein 101 Glycos_transf_1 PF00534.20 CDJ38137.1 - 7e-36 123.3 0.0 1.2e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ38137.1 - 6.7e-28 97.8 0.0 2.9e-27 95.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CDJ38137.1 - 7.9e-27 94.3 0.0 5.9e-26 91.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CDJ38137.1 - 3.9e-20 72.9 0.1 1.2e-18 68.1 0.0 2.9 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 CDJ38137.1 - 6.9e-15 55.4 0.2 3.9e-07 30.0 0.0 2.6 1 1 1 2 2 2 2 Starch synthase catalytic domain Alpha-amylase_C PF02806.18 CDJ38137.1 - 8.7e-15 55.0 0.0 2e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Glyco_trans_1_2 PF13524.6 CDJ38137.1 - 0.0019 18.5 0.0 0.0049 17.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Helicase_C PF00271.31 CDJ38139.1 - 6.6e-06 26.4 0.0 6.6e-06 26.4 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Endostatin PF06482.11 CDJ38139.1 - 3.2 7.1 16.6 1.3 8.4 13.0 1.9 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin RR_TM4-6 PF06459.12 CDJ38139.1 - 3.5 7.4 21.0 2.8 7.7 16.5 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 IHABP4_N PF16174.5 CDJ38139.1 - 7.2 7.2 29.6 18 5.9 24.7 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Neur_chan_memb PF02932.16 CDJ38141.1 - 0.071 13.2 2.4 0.07 13.2 2.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 CDJ38141.1 - 1.2 9.1 6.8 1.6 8.7 6.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4407 PF14362.6 CDJ38141.1 - 1.4 8.2 16.3 0.31 10.4 13.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RskA PF10099.9 CDJ38142.1 - 0.42 10.9 22.6 0.13 12.6 3.4 2.7 3 0 0 3 3 3 0 Anti-sigma-K factor rskA CLAG PF03805.13 CDJ38143.1 - 0.0054 14.4 0.0 0.0077 13.9 0.0 1.2 1 0 0 1 1 1 1 Cytoadherence-linked asexual protein DNA_pol_delta_4 PF04081.13 CDJ38144.1 - 4.1e-17 62.7 0.0 6.4e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 TPPII_N PF12583.8 CDJ38144.1 - 0.81 10.3 7.1 0.24 12.0 2.9 1.9 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal AP2 PF00847.20 CDJ38146.1 - 8e-10 38.8 0.0 3.7e-09 36.7 0.0 2.3 1 1 0 1 1 1 1 AP2 domain Pullulanase_Ins PF18494.1 CDJ38146.1 - 0.13 12.7 0.7 0.66 10.5 0.0 2.6 1 1 0 1 1 1 0 Pullulanase Ins domain AAA_13 PF13166.6 CDJ38146.1 - 0.66 8.5 10.3 1.3 7.6 10.3 1.4 1 0 0 1 1 1 0 AAA domain Noggin PF05806.12 CDJ38146.1 - 5.6 6.8 10.2 0.47 10.3 4.5 2.1 2 0 0 2 2 2 0 Noggin IATP PF04568.12 CDJ38147.1 - 1 9.8 6.3 0.15 12.5 0.5 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP TFIIA PF03153.13 CDJ38147.1 - 7.4 6.5 52.4 2.8 7.8 21.2 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Peroxin-3 PF04882.12 CDJ38147.1 - 8.5 5.2 18.1 1.4 7.8 6.5 2.3 2 0 0 2 2 2 0 Peroxin-3 CHCH PF06747.13 CDJ38149.1 - 0.038 14.1 5.4 0.12 12.5 5.4 1.9 1 1 0 1 1 1 0 CHCH domain COX6B PF02297.17 CDJ38149.1 - 0.061 13.6 2.6 0.11 12.7 2.6 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb SPX PF03105.19 CDJ38149.1 - 1.1 9.1 12.7 1.2 8.9 12.7 1.3 1 1 0 1 1 1 0 SPX domain TraT PF05818.12 CDJ38149.1 - 2.4 7.8 7.0 6 6.5 7.0 1.6 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein LPP PF04728.13 CDJ38150.1 - 0.022 15.1 6.9 0.022 15.1 6.9 4.4 5 0 0 5 5 5 0 Lipoprotein leucine-zipper BLOC1_2 PF10046.9 CDJ38150.1 - 0.062 13.6 5.4 2.3 8.6 1.3 3.6 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG2 PF06148.11 CDJ38150.1 - 0.18 11.9 11.9 0.29 11.2 3.4 3.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 CDJ38150.1 - 0.98 9.6 12.8 0.32 11.2 1.2 4.4 5 0 0 5 5 5 0 Golgi transport complex subunit 5 DUF1664 PF07889.12 CDJ38150.1 - 3.3 7.8 6.5 5.1 7.2 1.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) SR-25 PF10500.9 CDJ38152.1 - 0.59 9.7 12.5 0.17 11.5 9.4 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sad1_UNC PF07738.13 CDJ38153.1 - 9.2e-23 80.7 0.0 9.4e-12 45.1 0.0 2.5 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF1091 PF06477.13 CDJ38153.1 - 0.03 14.8 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) TFIIA PF03153.13 CDJ38153.1 - 0.98 9.3 44.1 0.063 13.3 22.5 2.9 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 CDJ38154.1 - 0.12 12.0 10.0 0.15 11.7 10.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Cwf_Cwc_15 PF04889.12 CDJ38154.1 - 0.33 10.6 13.7 1.7 8.3 5.7 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Apt1 PF10351.9 CDJ38154.1 - 0.63 8.8 20.8 0.94 8.3 20.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ38154.1 - 0.81 9.5 25.0 0.98 9.3 25.0 1.1 1 0 0 1 1 1 0 SPX domain DUF4554 PF15091.6 CDJ38154.1 - 0.82 8.5 8.2 1 8.2 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) TFIIA PF03153.13 CDJ38154.1 - 1.6 8.7 16.4 2.1 8.2 16.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 CDJ38154.1 - 3.5 6.7 28.3 4.2 6.5 28.3 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3807 PF12720.7 CDJ38154.1 - 4.3 7.6 15.4 12 6.2 15.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3807) CI-B14_5a PF07347.12 CDJ38155.1 - 0.51 10.3 4.0 0.55 10.1 1.5 2.4 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF1645 PF07816.11 CDJ38155.1 - 1.4 9.4 6.7 0.2 12.2 2.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) CCSAP PF15748.5 CDJ38155.1 - 4 7.5 13.0 1.8 8.7 10.0 1.9 1 1 0 1 1 1 0 Centriole, cilia and spindle-associated Arnt_C PF18583.1 CDJ38156.1 - 0.03 13.9 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain Rcd1 PF04078.13 CDJ38157.1 - 3.7e-123 409.9 0.6 3.7e-123 409.9 0.6 1.6 2 0 0 2 2 2 1 Cell differentiation family, Rcd1-like Sec16 PF12932.7 CDJ38158.1 - 0.34 11.5 2.5 0.43 11.2 0.1 2.4 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region Spt20 PF12090.8 CDJ38158.1 - 5.4 6.6 17.8 1.7 8.2 4.8 2.5 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ38158.1 - 8.1 5.3 10.5 1.6 7.6 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) ABC_membrane PF00664.23 CDJ38160.1 - 3.8e-30 105.5 0.0 4.9e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region PAP1 PF08601.10 CDJ38161.1 - 0.0017 18.2 13.1 0.0017 18.2 13.1 2.1 1 1 1 2 2 2 1 Transcription factor PAP1 NAM-associated PF14303.6 CDJ38161.1 - 0.0062 17.3 11.0 0.0062 17.3 11.0 3.6 1 1 2 3 3 3 1 No apical meristem-associated C-terminal domain RskA PF10099.9 CDJ38161.1 - 9.3 6.5 38.0 2.4 8.4 23.0 2.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ38162.1 - 0.0085 15.7 4.6 0.78 9.3 1.0 2.1 2 0 0 2 2 2 2 Spt20 family SUIM_assoc PF16619.5 CDJ38162.1 - 0.089 12.9 0.4 0.089 12.9 0.4 2.9 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ38162.1 - 0.11 11.5 0.8 5.9 5.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) AAT PF03417.16 CDJ38163.1 - 0.52 10.0 2.7 0.74 9.5 2.7 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase TFIIA PF03153.13 CDJ38163.1 - 7.6 6.4 8.1 9 6.2 8.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TAP42 PF04177.12 CDJ38165.1 - 8.2e-52 176.3 0.9 1.1e-51 175.9 0.9 1.0 1 0 0 1 1 1 1 TAP42-like family STD1 PF17235.2 CDJ38165.1 - 0.0037 16.9 0.2 0.007 16.0 0.2 1.4 1 0 0 1 1 1 1 STD1/MTH1 SMI1_KNR4 PF09346.10 CDJ38165.1 - 0.069 13.5 0.3 4 7.8 0.2 2.3 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) WD40 PF00400.32 CDJ38166.1 - 1e-14 54.6 4.7 2e-05 25.2 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ38166.1 - 0.0066 16.7 0.0 1.9 8.9 0.0 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Sulfotransfer_4 PF17784.1 CDJ38166.1 - 0.065 13.0 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Metallophos PF00149.28 CDJ38167.1 - 1e-41 143.7 0.1 1.3e-41 143.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ38167.1 - 7.5e-22 77.5 0.5 1.8e-21 76.3 0.2 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Nop PF01798.18 CDJ38168.1 - 1.3e-81 273.5 0.0 1.3e-81 273.5 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CDJ38168.1 - 3.2e-13 49.8 0.0 3.2e-13 49.8 0.0 3.1 4 0 0 4 4 4 1 NOP5NT (NUC127) domain AAA_lid_9 PF17871.1 CDJ38168.1 - 0.01 15.7 8.6 0.01 15.7 8.6 2.5 1 1 1 2 2 2 0 AAA lid domain RNA_polI_A34 PF08208.11 CDJ38168.1 - 1.1 9.3 22.2 1.9 8.5 22.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 FancD2 PF14631.6 CDJ38168.1 - 3.8 4.8 11.1 5.3 4.3 11.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Cdh1_DBD_1 PF18196.1 CDJ38168.1 - 3.9 7.8 15.3 18 5.7 15.2 2.2 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 MFS_1 PF07690.16 CDJ38169.1 - 2.3e-25 89.3 35.6 2.3e-25 89.3 35.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ38169.1 - 2.7e-14 52.9 28.2 8.7e-14 51.2 28.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 CDJ38169.1 - 1.6e-09 36.7 24.0 4.2e-08 31.9 7.0 3.1 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family CAF1A PF12253.8 CDJ38170.1 - 0.0088 16.2 13.7 0.0088 16.2 13.7 2.9 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A LMBR1 PF04791.16 CDJ38170.1 - 8.6 5.1 8.5 1.1 8.1 2.7 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Shadoo PF14999.6 CDJ38171.1 - 0.003 17.6 0.4 0.003 17.6 0.4 7.9 6 1 2 8 8 8 1 Shadow of prion protein, neuroprotective CcmD PF04995.14 CDJ38171.1 - 1 9.5 0.0 1 9.5 0.0 3.2 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) SPX PF03105.19 CDJ38174.1 - 0.00028 20.9 6.2 0.14 12.0 6.2 2.5 1 1 0 1 1 1 1 SPX domain GET2 PF08690.10 CDJ38174.1 - 0.0012 18.6 0.0 0.0012 18.6 0.0 2.8 3 0 0 3 3 3 1 GET complex subunit GET2 DUF2052 PF09747.9 CDJ38174.1 - 2.3 8.3 6.1 5.6 7.1 1.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) TFIIA PF03153.13 CDJ38174.1 - 6.1 6.7 48.5 1.2 9.1 12.7 2.7 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hydrolase_4 PF12146.8 CDJ38175.1 - 3.5e-13 49.4 17.2 5.6e-07 29.1 0.9 4.7 5 0 0 5 5 5 3 Serine aminopeptidase, S33 TFIIA PF03153.13 CDJ38175.1 - 0.00056 20.0 61.7 0.00056 20.0 61.7 4.4 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit DUF3458_C PF17432.2 CDJ38176.1 - 8.3e-84 281.7 14.8 4.4e-83 279.3 14.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 CDJ38176.1 - 2.7e-32 112.1 0.0 5e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CDJ38176.1 - 2.2e-10 41.0 0.0 7.8e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF3458 PF11940.8 CDJ38176.1 - 2.2e-09 37.6 0.0 2.2e-09 37.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M61 PF05299.12 CDJ38176.1 - 0.22 11.9 1.9 0.37 11.2 0.0 2.4 2 0 0 2 2 2 0 M61 glycyl aminopeptidase PP2C PF00481.21 CDJ38177.1 - 7.8e-47 160.1 2.7 9.1e-43 146.7 0.0 2.7 2 1 1 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.12 CDJ38177.1 - 0.0068 16.4 0.1 0.19 11.7 0.0 2.6 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) SurA_N_3 PF13624.6 CDJ38177.1 - 0.11 12.3 2.1 0.23 11.3 2.1 1.4 1 0 0 1 1 1 0 SurA N-terminal domain SOG2 PF10428.9 CDJ38177.1 - 9.9 5.2 12.5 0.56 9.3 7.4 1.4 2 0 0 2 2 2 0 RAM signalling pathway protein Spt20 PF12090.8 CDJ38178.1 - 0.0058 16.3 4.6 0.0058 16.3 4.6 3.3 2 1 1 3 3 3 1 Spt20 family SUIM_assoc PF16619.5 CDJ38178.1 - 0.023 14.7 10.1 0.023 14.7 10.1 4.0 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PLA2_B PF01735.18 CDJ38178.1 - 0.051 12.0 0.0 0.091 11.2 0.0 1.4 1 0 0 1 1 1 0 Lysophospholipase catalytic domain DLIC PF05783.11 CDJ38178.1 - 3.7 6.3 14.0 6 5.6 14.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RRM_1 PF00076.22 CDJ38179.1 - 1.1e-11 44.3 0.3 1.9e-11 43.6 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ38179.1 - 1.4e-06 27.9 0.1 4.9e-06 26.1 0.2 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ38179.1 - 0.00016 21.4 0.2 0.00042 20.1 0.2 1.7 1 1 0 1 1 1 1 Occluded RNA-recognition motif REPA_OB_2 PF16900.5 CDJ38179.1 - 0.04 13.8 0.6 6.4 6.8 0.2 2.4 1 1 1 2 2 2 0 Replication protein A OB domain Methyltrans_RNA PF04452.14 CDJ38179.1 - 0.041 13.2 0.4 0.049 13.0 0.4 1.3 1 1 0 1 1 1 0 RNA methyltransferase Ribosomal_60s PF00428.19 CDJ38179.1 - 0.11 13.1 11.6 0.21 12.2 4.9 2.4 2 1 0 2 2 2 0 60s Acidic ribosomal protein PNISR PF15996.5 CDJ38180.1 - 1.1 9.5 29.1 1.4 9.1 29.1 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR MMR1 PF08505.10 CDJ38180.1 - 1.2 9.4 28.5 1.3 9.2 28.5 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4638 PF15472.6 CDJ38180.1 - 3.6 7.3 17.3 4.6 6.9 17.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) NST1 PF13945.6 CDJ38180.1 - 4 7.5 29.1 6.2 6.9 29.1 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator RRM_1 PF00076.22 CDJ38181.1 - 0.0044 16.8 0.0 0.005 16.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CDJ38181.1 - 0.0053 16.9 0.0 0.0057 16.8 0.0 1.1 1 0 0 1 1 1 1 RRM-like domain Helicase_C PF00271.31 CDJ38182.1 - 2.1e-24 86.0 0.2 8.2e-24 84.1 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Nepo_coat_C PF03688.14 CDJ38183.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain Pkinase PF00069.25 CDJ38184.1 - 4.7e-69 232.7 0.0 6.2e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ38184.1 - 2.1e-31 109.1 0.0 3e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ38184.1 - 8.9e-30 100.0 4.5 1.3e-07 30.6 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ38184.1 - 2.3e-25 88.8 0.8 5.3e-12 46.0 0.0 3.4 4 0 0 4 4 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ38184.1 - 5e-24 82.1 0.5 1.9e-06 27.3 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDJ38184.1 - 4.9e-22 76.4 5.2 3e-06 26.5 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CDJ38184.1 - 1.2e-18 66.6 7.4 2e-07 30.7 0.4 4.5 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CDJ38184.1 - 9.3e-07 28.8 0.9 0.0071 16.3 0.0 3.2 2 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand APH PF01636.23 CDJ38184.1 - 2.4e-05 24.4 0.0 0.009 16.0 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family SPARC_Ca_bdg PF10591.9 CDJ38184.1 - 2.7e-05 24.4 0.0 0.051 13.9 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 CDJ38184.1 - 3e-05 23.5 0.0 0.00044 19.6 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ38184.1 - 3.7e-05 23.2 0.0 7.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.6 CDJ38184.1 - 0.00031 21.0 0.0 0.022 15.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain DUF2267 PF10025.9 CDJ38184.1 - 0.00034 20.9 0.2 0.1 12.9 0.0 3.1 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2267) TerB PF05099.13 CDJ38184.1 - 0.12 12.3 0.0 0.59 10.1 0.0 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB Spt20 PF12090.8 CDJ38185.1 - 0.0014 18.3 15.6 0.0014 18.3 15.6 2.8 2 0 0 2 2 2 1 Spt20 family XRN_M PF17846.1 CDJ38185.1 - 0.061 12.3 3.1 0.13 11.2 3.1 1.4 1 0 0 1 1 1 0 Xrn1 helical domain FAM176 PF14851.6 CDJ38185.1 - 0.15 11.7 2.1 0.57 9.8 2.1 2.0 1 0 0 1 1 1 0 FAM176 family GREB1 PF15782.5 CDJ38185.1 - 0.52 7.4 13.1 0.018 12.2 4.2 2.1 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Gti1_Pac2 PF09729.9 CDJ38185.1 - 0.65 10.1 9.4 0.11 12.5 1.1 2.8 3 0 0 3 3 3 0 Gti1/Pac2 family TMEM208_SND2 PF05620.11 CDJ38185.1 - 0.71 9.6 6.2 2.4 7.9 6.2 1.9 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF4692 PF15763.5 CDJ38185.1 - 0.94 9.9 19.4 3.9 7.9 4.2 3.5 3 0 0 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) FAM60A PF15396.6 CDJ38185.1 - 2 8.4 8.8 0.19 11.7 1.7 2.5 3 0 0 3 3 3 0 Protein Family FAM60A Presenilin PF01080.17 CDJ38185.1 - 2.8 6.6 17.6 1.5 7.5 9.2 2.4 2 0 0 2 2 2 0 Presenilin AAA_23 PF13476.6 CDJ38185.1 - 5.9 7.3 11.6 1.5 9.3 4.9 2.2 2 0 0 2 2 2 0 AAA domain Connexin PF00029.19 CDJ38185.1 - 8.6 6.0 6.8 2 8.1 3.3 1.6 2 0 0 2 2 2 0 Connexin IBN_N PF03810.19 CDJ38186.1 - 2.2e-10 40.3 0.0 2.2e-10 40.3 0.0 2.6 2 1 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 CDJ38186.1 - 6.9e-06 25.1 0.0 1.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 CDJ38186.1 - 0.014 15.5 2.3 0.014 15.5 2.3 2.5 2 1 0 2 2 2 0 Exportin 1-like protein Ribosomal_60s PF00428.19 CDJ38186.1 - 0.051 14.2 20.7 0.091 13.4 4.2 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein Glyco_hydro_9 PF00759.19 CDJ38186.1 - 0.16 11.3 3.9 0.16 11.3 0.7 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 TFIIA PF03153.13 CDJ38186.1 - 1.1 9.2 8.8 0.51 10.3 2.4 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ38186.1 - 2.4 8.4 27.4 6.6 7.0 10.2 4.1 3 1 0 3 3 3 0 Anti-sigma-K factor rskA Shadoo PF14999.6 CDJ38186.1 - 9.8 6.3 10.6 20 5.3 0.9 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective SR-25 PF10500.9 CDJ38187.1 - 0.00021 21.0 1.9 0.0003 20.5 1.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Sacchrp_dh_NADP PF03435.18 CDJ38187.1 - 0.0072 16.6 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAM104 PF15434.6 CDJ38187.1 - 0.032 14.8 4.0 0.059 13.9 4.0 1.4 1 0 0 1 1 1 0 Family 104 IMUP PF15761.5 CDJ38187.1 - 0.088 13.5 4.9 0.19 12.4 4.9 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Presenilin PF01080.17 CDJ38189.1 - 0.0065 15.3 23.5 0.019 13.7 23.5 1.8 1 0 0 1 1 1 1 Presenilin Otopetrin PF03189.13 CDJ38189.1 - 0.02 13.8 0.3 22 3.7 6.8 2.3 1 1 1 2 2 2 0 Otopetrin Pex14_N PF04695.13 CDJ38189.1 - 0.02 15.6 12.3 0.02 15.6 12.3 3.9 3 1 1 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2151 PF10221.9 CDJ38189.1 - 0.44 9.1 12.6 0.64 8.5 12.6 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator WTX PF09422.10 CDJ38189.1 - 0.51 9.4 21.3 1.2 8.2 21.3 1.5 1 0 0 1 1 1 0 WTX protein LMBR1 PF04791.16 CDJ38189.1 - 0.68 8.8 9.5 0.042 12.8 2.0 2.4 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF4484 PF14831.6 CDJ38189.1 - 5.4 7.0 29.8 13 5.7 29.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) BIRC6 PF12356.8 CDJ38189.1 - 7.1 6.0 10.5 0.48 9.8 1.2 2.3 2 0 0 2 2 2 0 Baculoviral IAP repeat-containing protein 6 GramPos_pilinD1 PF16555.5 CDJ38189.1 - 7.4 6.7 14.0 21 5.2 14.0 1.8 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain FbpA PF05833.11 CDJ38190.1 - 7.4e-15 54.6 17.3 1.1e-12 47.5 0.1 4.1 4 1 1 5 5 5 2 Fibronectin-binding protein A N-terminus (FbpA) ArsP_1 PF03773.13 CDJ38190.1 - 1.6 7.8 5.9 0.21 10.7 0.0 2.5 3 0 0 3 3 3 0 Predicted permease Jiraiya PF15038.6 CDJ38190.1 - 3.6 7.0 9.5 0.2 11.1 1.1 3.1 3 0 0 3 3 3 0 Jiraiya Kinesin PF00225.23 CDJ38191.1 - 1.9e-61 207.8 0.2 1.9e-61 207.8 0.2 3.0 1 1 3 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ38191.1 - 1.2e-11 44.7 1.0 1.2e-11 44.7 1.0 2.2 2 1 0 2 2 2 1 Microtubule binding SWI-SNF_Ssr4 PF08549.10 CDJ38191.1 - 0.0026 16.5 8.5 0.0035 16.1 8.5 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) GAS PF13851.6 CDJ38191.1 - 0.012 14.9 20.1 0.012 14.9 20.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 CDJ38191.1 - 0.013 15.6 15.9 0.034 14.2 15.9 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 CDJ38191.1 - 0.015 15.1 12.6 0.029 14.2 12.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Sec34 PF04136.15 CDJ38191.1 - 0.016 15.1 8.9 0.016 15.1 8.9 2.2 2 0 0 2 2 2 0 Sec34-like family V_ATPase_I PF01496.19 CDJ38191.1 - 0.022 12.7 5.4 0.024 12.6 5.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.22 CDJ38191.1 - 0.024 14.8 14.2 0.024 14.8 14.2 2.4 3 0 0 3 3 1 0 Seryl-tRNA synthetase N-terminal domain CALCOCO1 PF07888.11 CDJ38191.1 - 0.025 13.5 12.1 0.034 13.0 12.1 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DASH_Dam1 PF08653.10 CDJ38191.1 - 0.058 13.2 0.7 0.23 11.3 0.7 2.0 1 0 0 1 1 1 0 DASH complex subunit Dam1 Med9 PF07544.13 CDJ38191.1 - 0.075 13.1 10.8 0.22 11.7 10.8 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Laminin_II PF06009.12 CDJ38191.1 - 0.17 11.9 12.7 0.04 13.9 8.5 2.2 2 0 0 2 2 1 0 Laminin Domain II DUF4763 PF15960.5 CDJ38191.1 - 0.17 11.2 15.7 0.11 11.8 12.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Phage_GP20 PF06810.11 CDJ38191.1 - 0.18 11.6 14.4 0.59 9.9 14.4 1.9 1 0 0 1 1 1 0 Phage minor structural protein GP20 BRE1 PF08647.11 CDJ38191.1 - 0.19 11.8 21.2 0.049 13.7 17.0 2.3 2 1 0 2 2 1 0 BRE1 E3 ubiquitin ligase FapA PF03961.13 CDJ38191.1 - 0.2 10.3 11.9 0.32 9.5 11.9 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Occludin_ELL PF07303.13 CDJ38191.1 - 0.24 12.2 16.1 0.046 14.4 12.4 1.8 2 0 0 2 2 1 0 Occludin homology domain Fmp27_WPPW PF10359.9 CDJ38191.1 - 0.26 10.1 9.4 0.35 9.7 9.4 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMP_2 PF06791.13 CDJ38191.1 - 0.4 10.3 8.0 1.1 8.9 1.0 2.5 2 1 0 2 2 2 0 Prophage tail length tape measure protein TMPIT PF07851.13 CDJ38191.1 - 0.62 9.3 10.9 0.9 8.7 10.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein BLOC1_2 PF10046.9 CDJ38191.1 - 0.62 10.4 15.4 0.26 11.6 9.4 3.2 3 1 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_L PF02601.15 CDJ38191.1 - 0.63 9.6 8.8 1.2 8.6 8.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF812 PF05667.11 CDJ38191.1 - 0.67 8.8 18.0 1.1 8.1 18.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HemX PF04375.14 CDJ38191.1 - 0.78 9.0 13.3 1.7 7.8 13.3 1.6 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Spc7 PF08317.11 CDJ38191.1 - 0.79 8.5 18.9 1 8.2 18.4 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Spectrin PF00435.21 CDJ38191.1 - 0.8 10.2 14.5 0.65 10.5 10.9 2.6 2 1 1 3 3 2 0 Spectrin repeat ESM4 PF15952.5 CDJ38191.1 - 1.1 9.6 11.2 2.2 8.7 11.2 1.5 1 0 0 1 1 1 0 Enhancer of split M4 family NPV_P10 PF05531.12 CDJ38191.1 - 1.2 9.7 9.4 0.32 11.5 4.3 2.7 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Phage_GPO PF05929.11 CDJ38191.1 - 1.4 8.5 10.5 3.7 7.1 10.6 1.7 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FlaC_arch PF05377.11 CDJ38191.1 - 1.5 9.3 11.5 0.22 12.0 5.2 3.0 3 1 1 4 4 1 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 CDJ38191.1 - 1.6 8.0 18.3 1.6 8.0 16.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.15 CDJ38191.1 - 1.7 8.5 16.0 1.1 9.0 4.7 3.2 2 1 1 3 3 2 0 Septum formation initiator COG2 PF06148.11 CDJ38191.1 - 1.7 8.7 9.7 0.57 10.3 6.2 2.1 2 0 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2935 PF11155.8 CDJ38191.1 - 1.8 8.9 6.7 3.4 8.0 5.0 2.2 3 0 0 3 3 2 0 Domain of unknown function (DUF2935) Fib_alpha PF08702.10 CDJ38191.1 - 1.8 8.7 12.3 4.7 7.4 8.2 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 CDJ38191.1 - 2 8.6 21.4 0.13 12.5 16.0 1.9 2 0 0 2 2 1 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 CDJ38191.1 - 2.8 8.0 16.3 8.3 6.5 16.3 1.9 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PRKG1_interact PF15898.5 CDJ38191.1 - 3.3 8.7 15.3 8.2 7.4 14.3 2.3 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4407 PF14362.6 CDJ38191.1 - 3.3 7.0 12.6 6.1 6.1 12.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 CDJ38191.1 - 3.4 6.5 7.4 4.5 6.1 7.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PCRF PF03462.18 CDJ38191.1 - 3.7 7.4 15.3 2.3 8.1 12.4 1.9 1 1 1 2 2 2 0 PCRF domain Jnk-SapK_ap_N PF09744.9 CDJ38191.1 - 3.8 7.7 20.6 1.9 8.7 17.0 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 bZIP_1 PF00170.21 CDJ38191.1 - 3.9 7.7 13.1 0.26 11.4 6.3 2.4 2 0 0 2 2 2 0 bZIP transcription factor Noelin-1 PF12308.8 CDJ38191.1 - 5.5 7.0 9.1 21 5.2 7.1 2.6 2 1 1 3 3 2 0 Neurogenesis glycoprotein DUF2203 PF09969.9 CDJ38191.1 - 6.1 7.6 11.0 37 5.1 10.4 2.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TipAS PF07739.13 CDJ38191.1 - 6.1 7.4 12.2 2 9.0 9.0 1.9 2 0 0 2 2 1 0 TipAS antibiotic-recognition domain Spc24 PF08286.11 CDJ38191.1 - 6.3 7.1 16.0 1.6e+03 -0.7 15.0 2.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 YabA PF06156.13 CDJ38191.1 - 6.5 7.4 12.9 33 5.2 12.0 2.7 2 1 0 2 2 2 0 Initiation control protein YabA DUF1664 PF07889.12 CDJ38191.1 - 8.3 6.5 12.0 2.7 8.1 4.5 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) DUF4298 PF14131.6 CDJ38191.1 - 8.8 6.4 11.2 1.1e+02 2.9 11.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4298) HAUS6_N PF14661.6 CDJ38191.1 - 8.9 5.8 11.9 17 4.9 11.9 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus EIIBC-GUT_N PF03612.14 CDJ38192.1 - 0.0077 16.0 3.5 0.0081 15.9 3.5 1.0 1 0 0 1 1 1 1 Sorbitol phosphotransferase enzyme II N-terminus PAC1 PF16094.5 CDJ38192.1 - 0.0092 15.2 0.3 0.01 15.1 0.3 1.0 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 DUF2859 PF11072.8 CDJ38192.1 - 0.011 15.5 1.9 0.011 15.5 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) Tsg PF04668.12 CDJ38192.1 - 0.012 16.2 2.2 0.015 16.0 2.2 1.1 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region Rpp20 PF12328.8 CDJ38192.1 - 0.014 15.4 3.8 0.015 15.2 3.8 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P INSIG PF07281.12 CDJ38192.1 - 0.027 14.1 0.1 0.03 14.0 0.1 1.1 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) XRN_N PF03159.18 CDJ38192.1 - 0.036 13.5 1.7 0.043 13.2 1.7 1.0 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Nop53 PF07767.11 CDJ38192.1 - 0.049 13.0 10.5 0.051 13.0 10.5 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF3464 PF11947.8 CDJ38192.1 - 0.078 12.7 4.0 0.076 12.8 4.0 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Glt_symporter PF03616.14 CDJ38192.1 - 0.099 11.3 0.3 0.1 11.3 0.3 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter Orf78 PF06024.12 CDJ38192.1 - 0.1 12.9 1.0 0.1 12.9 1.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) CPSF100_C PF13299.6 CDJ38192.1 - 0.11 12.6 3.5 0.12 12.6 3.5 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.13 CDJ38192.1 - 0.13 12.9 9.6 0.14 12.9 9.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FHIPEP PF00771.20 CDJ38192.1 - 0.16 10.4 3.1 0.16 10.4 3.1 1.0 1 0 0 1 1 1 0 FHIPEP family Ndc1_Nup PF09531.10 CDJ38192.1 - 0.23 10.1 4.3 0.23 10.1 4.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2232 PF09991.9 CDJ38192.1 - 0.23 10.6 0.4 0.25 10.5 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) TFIIA PF03153.13 CDJ38192.1 - 0.36 10.8 19.3 0.34 10.8 19.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ38192.1 - 0.37 9.5 5.8 0.37 9.5 5.8 1.1 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 CDJ38192.1 - 0.39 10.7 8.1 0.39 10.8 8.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Suf PF05843.14 CDJ38192.1 - 0.39 10.6 9.3 0.39 10.6 9.3 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ38192.1 - 0.42 10.2 24.0 0.46 10.1 24.0 1.0 1 0 0 1 1 1 0 Spt20 family DUF5349 PF17298.2 CDJ38192.1 - 0.43 10.3 7.6 0.45 10.2 7.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF2722 PF10846.8 CDJ38192.1 - 0.52 9.2 18.4 0.55 9.1 18.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FAM199X PF15814.5 CDJ38192.1 - 0.52 9.3 6.9 0.53 9.3 6.9 1.1 1 0 0 1 1 1 0 Protein family FAM199X TMEM51 PF15345.6 CDJ38192.1 - 0.55 10.0 7.1 0.64 9.8 7.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Med3 PF11593.8 CDJ38192.1 - 1 8.5 18.7 1 8.5 18.7 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Neur_chan_memb PF02932.16 CDJ38192.1 - 1.3 9.1 4.2 1.3 9.0 4.2 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rrn6 PF10214.9 CDJ38192.1 - 1.3 7.4 10.4 1.3 7.4 10.4 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor UPF0560 PF10577.9 CDJ38192.1 - 1.7 7.0 10.4 1.7 7.1 10.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Roughex PF06020.11 CDJ38192.1 - 2.3 7.2 8.6 2.3 7.2 8.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Coilin_N PF15862.5 CDJ38192.1 - 2.7 7.8 12.7 3.3 7.5 12.7 1.1 1 0 0 1 1 1 0 Coilin N-terminus DUF4834 PF16118.5 CDJ38192.1 - 4.1 8.4 9.8 5.3 8.1 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) eIF-3_zeta PF05091.12 CDJ38192.1 - 4.9 6.0 11.7 5.2 5.9 11.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Activator_LAG-3 PF11498.8 CDJ38192.1 - 6 5.7 27.2 6.1 5.7 27.2 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Androgen_recep PF02166.16 CDJ38192.1 - 7.7 5.2 19.2 8.1 5.2 19.2 1.2 1 0 0 1 1 1 0 Androgen receptor Helicase_C PF00271.31 CDJ38193.1 - 3.1e-14 53.3 0.0 1.4e-13 51.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3240 PF11582.8 CDJ38193.1 - 0.02 15.0 0.2 0.41 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3240) PCM1_C PF15717.5 CDJ38193.1 - 0.16 10.7 1.3 0.31 9.7 1.3 1.4 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus FAM196 PF15265.6 CDJ38193.1 - 2.3 7.6 5.2 3.7 6.9 5.2 1.3 1 0 0 1 1 1 0 FAM196 family SAP25 PF15476.6 CDJ38193.1 - 3.9 7.1 11.8 0.038 13.7 3.2 2.1 2 1 0 2 2 2 0 Histone deacetylase complex subunit SAP25 DUF2722 PF10846.8 CDJ38195.1 - 0.00045 19.3 0.3 0.00045 19.3 0.3 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) DUF5411 PF17424.2 CDJ38195.1 - 0.0071 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5411) SUIM_assoc PF16619.5 CDJ38195.1 - 0.018 15.1 4.2 0.018 15.1 4.2 4.2 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF3506 PF12014.8 CDJ38195.1 - 1.4 8.9 5.0 0.88 9.6 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3506) Med15 PF09606.10 CDJ38195.1 - 1.7 7.3 23.3 2.3 6.8 4.5 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal RNA_pol_Rbc25 PF08292.12 CDJ38195.1 - 2.6 8.3 11.1 2.6 8.3 0.5 3.2 3 0 0 3 3 3 0 RNA polymerase III subunit Rpc25 Suf PF05843.14 CDJ38195.1 - 5 7.0 14.6 2.3 8.1 2.5 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Hydin_ADK PF17213.3 CDJ38195.1 - 5.1 7.3 10.0 2.5 8.3 0.2 3.1 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain Pex14_N PF04695.13 CDJ38195.1 - 7 7.3 28.5 0.12 13.1 6.3 3.2 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hist_deacetyl PF00850.19 CDJ38196.1 - 9.4e-81 271.6 0.0 1.1e-80 271.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain HXXSHH PF07586.11 CDJ38197.1 - 0.1 12.1 1.0 0.17 11.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) RNA_pol_A_bac PF01000.26 CDJ38198.1 - 5.4e-24 84.7 0.0 1.2e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CDJ38198.1 - 3.4e-15 55.2 0.0 7e-15 54.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 CDJ38198.1 - 0.0036 17.4 0.4 0.0083 16.3 0.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 CDJ38198.1 - 0.071 13.7 0.7 0.15 12.7 0.7 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain GMP_synt_C PF00958.22 CDJ38199.1 - 4.6e-36 122.7 0.0 1.1e-35 121.6 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CDJ38199.1 - 1.4e-30 106.5 0.0 3.1e-30 105.4 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CDJ38199.1 - 5.3e-07 29.6 0.1 3.7e-06 26.9 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 CDJ38199.1 - 8.3e-07 28.4 0.0 0.002 17.3 0.0 2.4 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.16 CDJ38199.1 - 0.00065 18.6 0.0 0.0016 17.3 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 CDJ38199.1 - 0.024 14.3 0.1 0.069 12.8 0.0 1.7 2 0 0 2 2 2 0 Asparagine synthase QueC PF06508.13 CDJ38199.1 - 0.028 13.9 0.0 5.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.14 CDJ38199.1 - 0.033 13.8 0.0 0.52 9.9 0.0 2.1 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 CDJ38199.1 - 0.047 13.7 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family DJ-1_PfpI PF01965.24 CDJ38199.1 - 0.06 13.2 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 DJ-1/PfpI family Ribosomal_60s PF00428.19 CDJ38199.1 - 9.8 6.8 13.6 41 4.9 13.6 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-rbx1 PF12678.7 CDJ38200.1 - 2.3e-05 24.6 6.2 9.2e-05 22.7 6.2 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CDJ38200.1 - 0.00011 22.5 5.0 0.00034 20.9 5.0 1.9 1 0 0 1 1 1 1 Ring finger domain SUIM_assoc PF16619.5 CDJ38200.1 - 0.00044 20.3 1.8 0.00044 20.3 1.8 24.3 21 2 3 24 24 24 4 Unstructured region C-term to UIM in Ataxin3 zf-ANAPC11 PF12861.7 CDJ38200.1 - 0.012 15.7 1.6 0.03 14.4 1.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CDJ38200.1 - 0.013 15.4 4.4 0.039 13.8 4.4 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ38200.1 - 0.048 13.5 4.1 0.14 12.1 4.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CDJ38200.1 - 0.12 12.6 4.0 0.29 11.3 4.0 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 CDJ38200.1 - 0.2 11.8 4.3 0.6 10.3 4.3 1.8 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 CDJ38200.1 - 0.35 11.2 6.2 1.1 9.6 6.2 1.9 1 0 0 1 1 1 0 RING-like domain AP2 PF00847.20 CDJ38201.1 - 3e-21 75.4 4.4 1.3e-12 47.7 0.7 4.4 5 0 0 5 5 5 2 AP2 domain DUF3399 PF11879.8 CDJ38201.1 - 0.0028 17.9 1.5 0.0028 17.9 1.5 3.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3399) AAA_6 PF12774.7 CDJ38201.1 - 0.16 10.9 0.5 0.28 10.1 0.5 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region DUF677 PF05055.12 CDJ38201.1 - 0.37 9.6 0.0 0.37 9.6 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF677) ANAPC4 PF12896.7 CDJ38201.1 - 1.3 8.5 3.9 6.7 6.2 0.8 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Peptidase_S64 PF08192.11 CDJ38201.1 - 2.4 6.5 10.2 2.8 6.3 0.2 2.4 2 0 0 2 2 2 0 Peptidase family S64 XPG_I PF00867.18 CDJ38202.1 - 2.5e-12 47.0 0.1 5.3e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDJ38202.1 - 1.5e-11 44.7 0.0 5.1e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 XPG N-terminal domain DUF4179 PF13786.6 CDJ38202.1 - 5.1 7.7 11.3 1.1e+02 3.4 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4179) Rad51 PF08423.11 CDJ38203.1 - 7.1e-08 32.0 0.3 8.6e-07 28.5 0.1 2.4 2 1 0 2 2 2 1 Rad51 AAA_25 PF13481.6 CDJ38203.1 - 0.0011 18.6 0.1 0.0052 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CDJ38203.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 KaiC RecA PF00154.21 CDJ38203.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_22 PF13401.6 CDJ38203.1 - 0.17 12.1 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain COX6A PF02046.15 CDJ38204.1 - 0.31 11.5 5.9 2.2 8.8 5.9 2.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa LSM PF01423.22 CDJ38205.1 - 1.2e-16 60.1 0.8 1.9e-16 59.5 0.8 1.3 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 CDJ38205.1 - 1.8 9.1 6.2 2.7 8.6 6.2 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 HECT PF00632.25 CDJ38206.1 - 1e-68 232.1 0.0 1.6e-68 231.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 CDJ38206.1 - 4.1e-28 97.7 7.2 2.5e-09 37.6 0.0 7.0 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ38206.1 - 1.9e-15 56.2 16.9 8.5e-06 25.4 0.1 6.0 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat R_equi_Vir PF05526.11 CDJ38206.1 - 4.2 7.2 7.7 0.43 10.4 0.1 2.8 3 0 0 3 3 3 0 Rhodococcus equi virulence-associated protein tRNA-synt_1c PF00749.21 CDJ38207.1 - 1.4e-100 336.2 0.0 1.4e-100 336.2 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CDJ38207.1 - 2.9e-47 160.8 0.0 7.4e-47 159.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain MFS_1 PF07690.16 CDJ38208.1 - 1.1e-11 44.3 23.6 2e-10 40.2 24.2 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily FAM176 PF14851.6 CDJ38208.1 - 0.00063 19.4 0.2 0.092 12.4 0.1 2.4 2 0 0 2 2 2 1 FAM176 family LapA_dom PF06305.11 CDJ38208.1 - 0.0019 18.0 0.5 0.28 11.0 0.2 2.8 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain Connexin PF00029.19 CDJ38208.1 - 0.0052 16.6 1.3 0.0061 16.4 0.0 1.7 2 0 0 2 2 2 1 Connexin MAS20 PF02064.15 CDJ38208.1 - 0.0073 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 MAS20 protein import receptor DUF2681 PF10883.8 CDJ38208.1 - 0.02 15.3 0.3 0.41 11.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Semialdhyde_dhC PF02774.18 CDJ38208.1 - 0.064 13.3 0.6 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain MAP17 PF15807.5 CDJ38208.1 - 0.11 12.8 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Involucrin2 PF06994.11 CDJ38208.1 - 0.2 11.8 13.4 0.37 10.9 13.4 1.4 1 0 0 1 1 1 0 Involucrin DUF4131 PF13567.6 CDJ38208.1 - 5.6 6.6 9.1 6.1 6.5 0.6 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) DUF2040 PF09745.9 CDJ38209.1 - 8.1e-16 58.2 18.2 7.4e-15 55.1 7.6 3.2 4 0 0 4 4 4 2 Coiled-coil domain-containing protein 55 (DUF2040) XRN_N PF03159.18 CDJ38210.1 - 4.1e-54 183.6 0.0 1.2e-45 155.8 0.0 3.4 3 1 0 3 3 3 2 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CDJ38210.1 - 2.7e-42 145.3 0.9 2.6e-26 92.6 1.1 4.3 4 0 0 4 4 4 2 Xrn1 helical domain Aldo_ket_red PF00248.21 CDJ38211.1 - 1.1e-46 159.4 0.0 2.2e-42 145.2 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family DUF4054 PF13262.6 CDJ38211.1 - 2.5 8.1 6.0 0.29 11.2 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) EF-hand_7 PF13499.6 CDJ38212.1 - 6.5e-31 106.6 19.8 2.8e-09 37.3 0.3 4.0 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.32 CDJ38212.1 - 2.5e-29 98.6 14.8 1.1e-05 24.7 0.1 6.6 7 0 0 7 7 7 5 EF hand EF-hand_5 PF13202.6 CDJ38212.1 - 5.5e-27 92.0 14.8 2.9e-05 23.3 0.2 6.6 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 CDJ38212.1 - 4.4e-24 82.3 9.4 3.2e-05 23.5 0.1 6.7 6 1 0 6 6 6 5 EF-hand domain EF-hand_8 PF13833.6 CDJ38212.1 - 1e-13 50.9 10.7 0.035 14.0 0.1 5.9 6 0 0 6 6 6 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ38212.1 - 5.1e-11 42.9 4.8 0.011 16.0 0.1 3.3 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Unstab_antitox PF09720.10 CDJ38212.1 - 0.0011 18.9 0.3 0.0011 18.9 0.3 2.6 4 0 0 4 4 4 1 Putative addiction module component Dockerin_1 PF00404.18 CDJ38212.1 - 0.0043 17.2 3.9 1.3 9.3 0.5 3.8 2 2 2 4 4 4 1 Dockerin type I domain EF-hand_4 PF12763.7 CDJ38212.1 - 0.1 12.6 7.5 7.6 6.6 0.8 4.2 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand O-FucT PF10250.9 CDJ38212.1 - 0.11 12.2 0.2 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Fes1 PF08609.10 CDJ38212.1 - 0.51 11.3 8.6 1.9 9.4 1.1 3.2 2 1 1 3 3 3 0 Nucleotide exchange factor Fes1 DUF3349 PF11829.8 CDJ38212.1 - 0.83 10.5 4.2 6.6 7.6 0.0 2.9 3 1 1 4 4 3 0 Protein of unknown function (DUF3349) Mst1_SARAH PF11629.8 CDJ38212.1 - 1.6 8.9 6.2 5.6 7.1 0.2 3.6 4 0 0 4 4 4 0 C terminal SARAH domain of Mst1 NPA PF16469.5 CDJ38212.1 - 3.7 8.2 7.2 2 9.0 2.6 2.4 1 1 1 2 2 2 0 Nematode polyprotein allergen ABA-1 E1-E2_ATPase PF00122.20 CDJ38213.1 - 2.4e-12 46.8 0.0 2.9e-11 43.2 0.0 2.8 1 1 0 1 1 1 1 E1-E2 ATPase DUF2722 PF10846.8 CDJ38213.1 - 0.0017 17.4 34.4 0.002 17.1 0.1 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ38213.1 - 0.003 17.9 11.1 0.47 10.8 0.1 3.2 3 0 0 3 3 3 2 Enhancer of polycomb-like Pex14_N PF04695.13 CDJ38213.1 - 0.021 15.5 3.9 0.021 15.5 3.9 4.5 5 0 0 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.9 CDJ38213.1 - 0.16 12.3 0.1 0.16 12.3 0.1 7.3 3 2 3 7 7 7 0 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ38213.1 - 0.27 12.2 21.8 5.3 8.1 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Eapp_C PF10238.9 CDJ38213.1 - 1.3 9.1 20.5 0.65 10.1 3.3 3.5 3 0 0 3 3 3 0 E2F-associated phosphoprotein HATPase_c PF02518.26 CDJ38214.1 - 0.00041 20.8 0.0 0.0019 18.6 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UDG PF03167.19 CDJ38216.1 - 4.1e-21 75.6 0.0 7e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily TFIIA PF03153.13 CDJ38216.1 - 0.26 11.2 14.9 0.37 10.7 14.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.9 CDJ38216.1 - 0.59 8.9 22.7 0.8 8.5 22.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macoilin PF09726.9 CDJ38216.1 - 4.1 5.8 6.2 5.1 5.5 6.2 1.1 1 0 0 1 1 1 0 Macoilin family Spt20 PF12090.8 CDJ38216.1 - 7.2 6.2 12.6 11 5.5 12.6 1.3 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 CDJ38216.1 - 8.6 4.9 10.5 12 4.4 10.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC_tran PF00005.27 CDJ38218.1 - 1.7e-13 51.3 1.2 1.6e-11 44.9 1.2 2.3 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ38218.1 - 9.8e-09 35.0 0.2 1.2e-08 34.6 0.2 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CDJ38218.1 - 0.016 15.4 1.1 0.21 11.9 0.6 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SART-1 PF03343.13 CDJ38218.1 - 0.032 12.8 8.1 0.25 9.8 8.1 1.9 1 1 0 1 1 1 0 SART-1 family Presenilin PF01080.17 CDJ38218.1 - 0.12 11.1 2.4 0.15 10.8 2.4 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ38218.1 - 1 9.3 3.3 1.6 8.8 3.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ABC_tran PF00005.27 CDJ38219.1 - 1.1e-13 51.8 0.1 2.4e-13 50.8 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CDJ38219.1 - 1.1e-11 44.9 0.3 1.4e-11 44.6 0.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 CDJ38219.1 - 0.0002 21.8 0.0 0.00058 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ38219.1 - 0.0016 18.4 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CDJ38219.1 - 0.0018 18.0 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CDJ38219.1 - 0.0062 16.8 0.1 0.017 15.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 CDJ38219.1 - 0.0076 16.2 0.1 0.017 15.1 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 CDJ38219.1 - 0.008 16.3 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CDJ38219.1 - 0.011 15.3 0.4 0.02 14.5 0.4 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 CDJ38219.1 - 0.017 14.3 0.1 0.028 13.6 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit SspB PF04386.13 CDJ38219.1 - 0.019 14.9 1.8 0.051 13.5 1.8 1.7 1 0 0 1 1 1 0 Stringent starvation protein B AAA_8 PF12780.7 CDJ38219.1 - 0.029 13.7 0.0 0.077 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Spore_IV_A PF09547.10 CDJ38219.1 - 0.075 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) AAA_5 PF07728.14 CDJ38219.1 - 0.088 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.18 CDJ38219.1 - 0.1 11.8 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Septin Roc PF08477.13 CDJ38219.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 CDJ38219.1 - 0.13 12.3 0.0 0.94 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CDJ38219.1 - 0.16 12.0 0.1 0.53 10.3 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 CDJ38219.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 CDJ38219.1 - 0.43 10.3 0.0 0.43 10.3 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 CDJ38219.1 - 1.8 9.0 0.0 1.8 9.0 0.0 2.3 2 0 0 2 2 1 0 AAA domain PQQ PF01011.21 CDJ38222.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 PQQ enzyme repeat AP2 PF00847.20 CDJ38224.1 - 1.6e-08 34.6 3.0 0.0026 17.9 0.0 2.3 2 0 0 2 2 2 2 AP2 domain AP2 PF00847.20 CDJ38225.1 - 3.8e-24 84.7 1.8 1.1e-11 44.8 0.2 2.4 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.6 CDJ38225.1 - 4.3e-16 59.0 0.2 7.2e-16 58.3 0.2 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal Pkinase PF00069.25 CDJ38227.1 - 5.8e-48 163.6 0.0 7.7e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ38227.1 - 1.5e-43 149.0 0.0 2e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CDJ38227.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 CDJ38227.1 - 0.022 13.7 0.2 0.037 13.0 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CDJ38227.1 - 0.21 10.8 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Actin PF00022.19 CDJ38228.1 - 3.5e-144 480.4 0.0 1.5e-143 478.3 0.0 1.7 1 1 0 1 1 1 1 Actin MMR_HSR1 PF01926.23 CDJ38230.1 - 1.1e-13 51.2 0.0 2.9e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ38230.1 - 6.2e-05 22.6 0.0 0.00037 20.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 CDJ38230.1 - 8e-05 22.1 0.0 0.00026 20.4 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Septin PF00735.18 CDJ38230.1 - 0.019 14.3 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Septin Arf PF00025.21 CDJ38230.1 - 0.067 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Roc PF08477.13 CDJ38230.1 - 0.088 13.0 0.0 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CDJ38230.1 - 0.13 12.3 0.2 0.88 9.6 0.0 2.1 1 1 1 2 2 2 0 Dynamin family Med21 PF11221.8 CDJ38231.1 - 3.3e-08 33.9 1.9 3.7e-08 33.7 1.9 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF16 PF01519.16 CDJ38231.1 - 0.00099 19.6 0.6 0.0013 19.2 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF16 Phage_GP20 PF06810.11 CDJ38231.1 - 0.0024 17.7 0.2 0.0027 17.5 0.2 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 GCN5L1 PF06320.13 CDJ38231.1 - 0.0035 17.5 0.5 0.0045 17.1 0.5 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) UPF0184 PF03670.13 CDJ38231.1 - 0.0058 17.0 1.0 0.0087 16.4 0.4 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0184) LXG PF04740.12 CDJ38231.1 - 0.011 15.4 0.8 0.013 15.3 0.8 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily TPR_MLP1_2 PF07926.12 CDJ38231.1 - 0.013 15.5 3.1 0.023 14.8 3.1 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CREPT PF16566.5 CDJ38231.1 - 0.015 15.5 2.3 0.018 15.2 2.3 1.1 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Med4 PF10018.9 CDJ38231.1 - 0.027 14.2 1.1 0.041 13.6 1.1 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Sec34 PF04136.15 CDJ38231.1 - 0.045 13.6 0.5 0.055 13.4 0.5 1.2 1 0 0 1 1 1 0 Sec34-like family COMP PF11598.8 CDJ38231.1 - 0.047 14.2 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Med9 PF07544.13 CDJ38231.1 - 0.058 13.5 0.9 0.1 12.7 0.9 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Snapin_Pallidin PF14712.6 CDJ38231.1 - 0.12 12.8 1.5 0.24 11.9 1.5 1.6 1 1 0 1 1 1 0 Snapin/Pallidin zf-C4H2 PF10146.9 CDJ38231.1 - 0.32 11.3 2.1 0.38 11.0 2.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein APG6_N PF17675.1 CDJ38231.1 - 0.5 10.9 6.7 0.65 10.5 6.7 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region TSC22 PF01166.18 CDJ38231.1 - 0.64 10.4 9.7 2.9 8.3 4.1 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family TMIE PF16038.5 CDJ38233.1 - 4.7 7.1 7.6 14 5.6 7.6 1.7 1 0 0 1 1 1 0 TMIE protein TIG PF01833.24 CDJ38235.1 - 4.1e-05 23.6 0.4 8.4e-05 22.6 0.4 1.6 1 1 0 1 1 1 1 IPT/TIG domain Filamin PF00630.19 CDJ38235.1 - 0.00018 22.3 0.0 0.00057 20.7 0.0 1.8 2 1 0 2 2 2 1 Filamin/ABP280 repeat Kelch_5 PF13854.6 CDJ38235.1 - 0.0048 16.9 0.0 0.041 13.9 0.0 2.3 2 0 0 2 2 2 1 Kelch motif DHC_N2 PF08393.13 CDJ38236.1 - 1e-86 291.5 14.6 1e-86 291.5 14.6 2.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Filamin PF00630.19 CDJ38236.1 - 1.3e-05 25.9 0.0 3.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Filamin/ABP280 repeat DUF4094 PF13334.6 CDJ38236.1 - 2.6 8.5 6.4 0.63 10.5 0.5 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) AAA_6 PF12774.7 CDJ38237.1 - 3.9e-118 394.2 0.0 1.4e-66 224.7 0.1 2.0 1 1 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 CDJ38237.1 - 0.00094 19.2 0.0 0.0078 16.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ38237.1 - 0.0081 16.6 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDJ38237.1 - 0.099 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 CDJ38237.1 - 0.11 13.0 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ38238.1 - 7.1e-24 84.3 0.0 5.7e-22 78.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 CDJ38238.1 - 9.7e-20 71.0 0.7 2.1e-19 69.9 0.7 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDJ38238.1 - 5.5e-15 55.6 0.0 1.4e-11 44.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_6 PF12774.7 CDJ38238.1 - 2.6e-10 39.8 0.0 4.6e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 CDJ38238.1 - 5.9e-06 26.8 0.0 0.01 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CDJ38238.1 - 3.2e-05 24.2 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CDJ38238.1 - 3.4e-05 24.4 0.0 0.022 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CDJ38238.1 - 0.00026 21.2 0.2 0.66 10.1 0.1 2.4 2 1 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 CDJ38238.1 - 0.00053 19.8 0.0 0.35 10.6 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 CDJ38238.1 - 0.00084 19.2 0.1 0.81 9.4 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA PF00004.29 CDJ38238.1 - 0.00086 19.7 0.0 0.55 10.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CDJ38238.1 - 0.0018 17.6 0.1 0.48 9.7 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin ABC_tran PF00005.27 CDJ38238.1 - 0.007 16.9 0.0 1.4 9.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 CDJ38238.1 - 0.011 16.2 0.0 5.7 7.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 CDJ38238.1 - 0.013 15.3 0.0 0.39 10.4 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 CDJ38238.1 - 0.017 14.8 0.0 0.84 9.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 CDJ38238.1 - 0.019 15.0 0.0 0.62 10.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase KTI12 PF08433.10 CDJ38238.1 - 0.022 14.2 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 CDJ38238.1 - 0.027 14.2 0.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CDJ38238.1 - 0.03 14.3 0.1 0.6 10.1 0.0 2.5 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 CDJ38238.1 - 0.031 14.2 0.0 4.3 7.2 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MeaB PF03308.16 CDJ38238.1 - 0.041 12.9 0.0 0.084 11.8 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 CDJ38238.1 - 0.052 13.8 0.3 3.2 8.0 0.0 2.8 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 CDJ38238.1 - 0.11 11.7 0.0 12 5.0 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_19 PF13245.6 CDJ38238.1 - 0.11 12.9 0.0 2.9 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CDJ38238.1 - 0.11 11.9 0.0 0.79 9.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 CDJ38238.1 - 0.14 12.1 0.0 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 CDJ38238.1 - 0.16 11.7 0.0 15 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDJ38239.1 - 1.8e-22 79.7 0.1 3.4e-22 78.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_1 PF17857.1 CDJ38239.1 - 1.9e-18 66.5 0.7 5.5e-16 58.6 0.2 2.7 2 1 0 2 2 2 1 AAA+ lid domain AAA_8 PF12780.7 CDJ38240.1 - 1.1e-86 290.4 0.0 2e-86 289.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 CDJ38240.1 - 5.4e-77 259.1 14.2 8.2e-77 258.5 14.2 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 CDJ38240.1 - 2.9e-69 232.6 0.6 1.4e-51 174.7 0.2 3.5 3 1 0 3 3 3 2 ATP-binding dynein motor region Dynein_C PF18199.1 CDJ38240.1 - 1.1e-65 221.9 0.1 5.8e-65 219.5 0.1 2.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CDJ38240.1 - 4.1e-42 143.8 0.0 7.8e-42 142.9 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ38240.1 - 7.6e-34 116.4 0.0 1.5e-30 105.7 0.0 3.4 2 1 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain Laminin_II PF06009.12 CDJ38240.1 - 0.01 15.9 1.9 0.01 15.9 1.9 5.3 4 1 2 6 6 6 1 Laminin Domain II AAA_5 PF07728.14 CDJ38240.1 - 0.019 15.0 0.0 4 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF948 PF06103.11 CDJ38240.1 - 3.6 7.9 18.0 2.5 8.4 0.4 5.6 4 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Sec34 PF04136.15 CDJ38240.1 - 9.8 6.0 11.5 6.6 6.6 0.6 3.4 3 0 0 3 3 3 0 Sec34-like family DEAD PF00270.29 CDJ38241.1 - 5.2e-24 85.0 0.0 1.1e-23 83.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ38241.1 - 0.022 15.0 0.0 0.3 11.3 0.0 2.8 1 1 0 1 1 1 0 AAA domain DUF2694 PF10904.8 CDJ38241.1 - 0.025 14.7 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) SNF2_N PF00176.23 CDJ38241.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Abhydrolase_6 PF12697.7 CDJ38242.1 - 1.5e-24 87.8 1.0 2.3e-24 87.2 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ38242.1 - 2e-08 34.2 0.0 6.3e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ38242.1 - 1.3e-07 31.2 0.8 2.4e-06 27.0 0.8 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CDJ38242.1 - 0.0006 19.6 0.1 0.00098 18.9 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 CDJ38242.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 CDJ38242.1 - 0.027 14.6 0.4 0.33 11.0 0.0 2.6 3 0 0 3 3 3 0 Thioesterase domain Lipase_3 PF01764.25 CDJ38242.1 - 0.034 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Wzy_C PF04932.15 CDJ38243.1 - 0.004 16.8 0.2 0.48 10.0 0.0 2.8 3 0 0 3 3 3 1 O-Antigen ligase SUR7 PF06687.12 CDJ38243.1 - 0.024 14.3 15.8 0.062 12.9 0.9 3.2 3 0 0 3 3 3 0 SUR7/PalI family DUF2207 PF09972.9 CDJ38243.1 - 0.028 13.2 6.2 1.4 7.6 0.1 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) FAM176 PF14851.6 CDJ38243.1 - 0.054 13.2 0.0 0.054 13.2 0.0 3.4 3 0 0 3 3 3 0 FAM176 family Phage_holin_3_6 PF07332.11 CDJ38243.1 - 0.74 9.9 21.7 0.071 13.2 1.0 3.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 CDJ38243.1 - 0.9 9.2 12.7 0.39 10.3 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Saf_2TM PF18303.1 CDJ38243.1 - 3.7 7.1 6.4 12 5.5 0.0 3.0 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain Prominin PF05478.11 CDJ38243.1 - 6.7 4.5 14.5 18 3.1 14.5 1.7 1 0 0 1 1 1 0 Prominin HMA PF00403.26 CDJ38244.1 - 1.4e-07 31.8 0.5 3.6e-06 27.3 0.0 2.9 2 1 1 3 3 3 1 Heavy-metal-associated domain B1 PF02246.15 CDJ38244.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein L b1 domain E1-E2_ATPase PF00122.20 CDJ38245.1 - 1.5e-18 66.9 8.0 2.2e-13 50.1 0.0 2.3 2 0 0 2 2 2 2 E1-E2 ATPase US30 PF17624.2 CDJ38245.1 - 0.06 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function Hydrolase PF00702.26 CDJ38245.1 - 0.061 13.6 1.0 0.18 12.1 0.1 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase ABC2_membrane_2 PF12679.7 CDJ38245.1 - 0.86 8.8 4.0 4.1 6.6 2.6 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Hydrolase PF00702.26 CDJ38246.1 - 1.3e-14 55.0 0.0 4.5e-12 46.7 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ38246.1 - 0.0042 16.8 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase SLATT_1 PF18181.1 CDJ38246.1 - 1.2 9.1 7.0 0.14 12.1 1.3 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Bacillus_PapR PF05968.11 CDJ38246.1 - 3 7.8 5.5 20 5.2 0.5 2.7 2 0 0 2 2 2 0 Bacillus PapR protein ArfGap PF01412.18 CDJ38247.1 - 7.6e-30 103.4 1.3 1.2e-29 102.7 0.1 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf ABC2_membrane_2 PF12679.7 CDJ38247.1 - 0.86 8.8 3.5 1.4 8.1 3.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein MccV PF17508.2 CDJ38247.1 - 5.4 7.6 8.2 5.5 7.6 6.1 2.0 2 0 0 2 2 2 0 Microcin V bacteriocin SARAF PF06682.12 CDJ38248.1 - 0.0035 17.1 11.0 0.0035 17.1 11.0 2.4 1 1 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis Glyoxal_oxid_N PF07250.11 CDJ38248.1 - 0.26 10.5 1.6 0.48 9.6 1.6 1.4 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus TFIIA PF03153.13 CDJ38249.1 - 0.079 12.9 75.0 0.082 12.9 27.5 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Proteasome PF00227.26 CDJ38252.1 - 1e-43 149.0 0.0 1.2e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4100 PF13352.6 CDJ38253.1 - 3.8 7.2 16.0 0.094 12.5 7.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4100) SART-1 PF03343.13 CDJ38253.1 - 4.6 5.7 28.3 6.4 5.2 28.3 1.1 1 0 0 1 1 1 0 SART-1 family Hc1 PF07432.13 CDJ38254.1 - 0.56 10.6 11.3 0.89 9.9 11.3 1.3 1 0 0 1 1 1 0 Histone H1-like protein Hc1 DUF3275 PF11679.8 CDJ38254.1 - 1.6 8.7 6.2 2.2 8.2 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF3597 PF12200.8 CDJ38254.1 - 2.6 8.6 7.8 6.3 7.4 7.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) WD40 PF00400.32 CDJ38255.1 - 9.8e-19 67.4 3.6 0.0028 18.5 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.8 CDJ38255.1 - 0.00044 19.0 0.2 0.048 12.3 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CDJ38255.1 - 0.01 16.1 0.1 1.6 9.1 0.1 3.3 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1676 PF07898.13 CDJ38257.1 - 0.083 12.9 1.1 0.13 12.3 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) RskA PF10099.9 CDJ38257.1 - 0.17 12.1 8.2 1.7 8.9 8.2 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ38257.1 - 0.18 12.8 2.8 0.71 10.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Activator_LAG-3 PF11498.8 CDJ38258.1 - 0.0023 17.0 8.6 0.0023 17.0 8.6 3.3 2 1 1 3 3 3 1 Transcriptional activator LAG-3 RskA PF10099.9 CDJ38258.1 - 0.0031 17.8 24.3 0.19 12.0 0.0 3.3 1 1 1 3 3 3 2 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ38258.1 - 0.0091 15.6 50.2 0.086 12.4 7.2 3.5 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein Mannosyl_trans4 PF15971.5 CDJ38258.1 - 0.47 10.3 2.6 0.5 10.2 0.1 2.0 2 0 0 2 2 2 0 DolP-mannose mannosyltransferase EIF4E-T PF10477.9 CDJ38259.1 - 0.14 11.0 12.7 0.12 11.2 12.7 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Spt20 PF12090.8 CDJ38259.1 - 0.4 10.2 20.2 0.41 10.2 20.2 1.1 1 0 0 1 1 1 0 Spt20 family Fumble PF03630.14 CDJ38259.1 - 0.43 9.7 1.5 0.47 9.6 1.5 1.0 1 0 0 1 1 1 0 Fumble DUF2722 PF10846.8 CDJ38259.1 - 0.86 8.5 14.4 0.74 8.7 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ38259.1 - 2.8 7.9 23.7 2.8 7.9 23.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 CDJ38259.1 - 6.6 6.7 10.2 6.5 6.7 10.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF5327 PF17261.2 CDJ38259.1 - 6.7 7.5 17.2 1.8 9.3 5.8 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5327) Phage_HK97_TLTM PF06120.11 CDJ38261.1 - 2.1e-06 27.1 3.0 0.3 10.2 0.1 3.6 1 1 3 4 4 4 3 Tail length tape measure protein NECFESHC PF16621.5 CDJ38261.1 - 9.7e-06 25.5 9.8 6.1 6.9 0.1 5.3 4 0 0 4 4 4 4 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 mRNA_triPase PF02940.15 CDJ38261.1 - 0.0004 20.2 19.1 0.59 9.8 0.5 4.1 4 0 0 4 4 4 3 mRNA capping enzyme, beta chain G2BR PF18442.1 CDJ38261.1 - 0.0033 17.0 2.8 1.4e+02 2.2 0.0 6.3 6 0 0 6 6 6 0 E3 gp78 Ube2g2-binding region (G2BR) PCYCGC PF13798.6 CDJ38261.1 - 0.0068 16.3 8.5 11 5.8 0.1 4.1 4 0 0 4 4 4 2 Protein of unknown function with PCYCGC motif VD10_N PF08476.10 CDJ38261.1 - 0.012 15.3 5.6 46 3.8 0.1 4.1 4 0 0 4 4 4 0 Viral D10 N-terminal DUF4174 PF13778.6 CDJ38261.1 - 0.42 11.1 8.3 1.1e+02 3.3 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4174) TMEM132D_N PF15705.5 CDJ38261.1 - 1.9 8.4 7.3 17 5.2 0.2 3.5 4 0 0 4 4 4 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term Presenilin PF01080.17 CDJ38263.1 - 0.68 8.6 3.8 0.59 8.8 3.8 1.1 1 0 0 1 1 1 0 Presenilin EMC3_TMCO1 PF01956.16 CDJ38264.1 - 1.5e-28 99.7 1.8 2.4e-28 99.0 1.8 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like eIF3_subunit PF08597.10 CDJ38265.1 - 0.0086 16.0 12.4 0.028 14.3 12.4 1.8 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit RskA PF10099.9 CDJ38265.1 - 0.05 13.9 12.8 0.061 13.6 12.8 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ38265.1 - 0.15 12.7 25.8 0.14 12.7 8.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Stm1_N PF09598.10 CDJ38265.1 - 4.6 8.1 11.0 6.9 7.6 2.9 2.2 2 0 0 2 2 2 0 Stm1 RRM_1 PF00076.22 CDJ38266.1 - 4e-21 74.6 0.0 5.9e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 CDJ38266.1 - 7.5e-14 52.1 4.4 7.5e-14 52.1 4.4 2.7 3 1 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SNRNP27 PF08648.12 CDJ38267.1 - 1.2e-25 89.4 0.3 2.3e-25 88.4 0.3 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DUF4598 PF15370.6 CDJ38267.1 - 0.042 14.3 1.4 0.042 14.3 1.4 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4598) CDK2AP PF09806.9 CDJ38267.1 - 0.12 12.4 9.5 0.21 11.6 9.5 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PPDK_N PF01326.19 CDJ38268.1 - 2.1e-19 70.0 0.0 4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Macoilin PF09726.9 CDJ38268.1 - 0.02 13.5 8.0 0.015 13.9 4.2 2.2 2 0 0 2 2 2 0 Macoilin family MID_MedPIWI PF18296.1 CDJ38268.1 - 0.37 10.5 9.6 0.52 10.1 6.8 2.2 2 0 0 2 2 2 0 MID domain of medPIWI Apt1 PF10351.9 CDJ38268.1 - 1.8 7.3 13.3 1.7 7.4 9.9 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF1416 PF07210.12 CDJ38269.1 - 0.082 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) SR-25 PF10500.9 CDJ38269.1 - 0.78 9.3 12.0 0.065 12.8 1.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Mpp10 PF04006.12 CDJ38270.1 - 4.4e-42 144.4 126.5 1.4e-25 89.8 7.5 4.2 2 1 1 3 3 3 3 Mpp10 protein Glyco_hydro2_C5 PF18565.1 CDJ38271.1 - 0.084 12.7 0.4 0.097 12.5 0.4 1.2 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 Porin_4 PF13609.6 CDJ38271.1 - 0.11 12.3 4.8 0.12 12.1 4.8 1.1 1 0 0 1 1 1 0 Gram-negative porin FAM199X PF15814.5 CDJ38271.1 - 0.26 10.3 10.7 0.26 10.3 10.7 1.0 1 0 0 1 1 1 0 Protein family FAM199X Activator_LAG-3 PF11498.8 CDJ38272.1 - 0.048 12.6 12.8 0.05 12.6 12.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ38272.1 - 2.3 8.1 10.7 2.2 8.2 10.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PS_Dcarbxylase PF02666.15 CDJ38273.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase PS_Dcarbxylase PF02666.15 CDJ38274.1 - 3.2e-05 23.5 0.0 4.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase IF4E PF01652.18 CDJ38277.1 - 5.6e-14 52.2 0.0 9.1e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ER PF01133.17 CDJ38278.1 - 8.7e-28 96.2 0.0 9.5e-28 96.1 0.0 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Sterile PF03015.19 CDJ38279.1 - 8.5e-11 41.9 0.0 2.4e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 CDJ38279.1 - 6.6e-09 35.5 0.0 1.6e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase EIF4E-T PF10477.9 CDJ38279.1 - 0.29 9.9 5.5 0.44 9.3 5.5 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E TFIIA PF03153.13 CDJ38279.1 - 1.1 9.2 20.6 0.63 10.0 13.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ38279.1 - 3.4 8.7 5.5 7.9 7.5 5.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ANAPC_CDC26 PF10471.9 CDJ38279.1 - 4.3 8.2 19.2 21 6.0 15.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF3464 PF11947.8 CDJ38279.1 - 4.9 6.9 5.0 5.9 6.6 2.5 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DivIC PF04977.15 CDJ38279.1 - 8.8 6.2 10.8 25 4.7 10.8 1.7 1 0 0 1 1 1 0 Septum formation initiator OAD_gamma PF04277.13 CDJ38280.1 - 0.18 12.4 0.1 0.18 12.4 0.1 6.0 4 2 1 5 5 5 0 Oxaloacetate decarboxylase, gamma chain B12D PF06522.11 CDJ38281.1 - 0.18 11.6 0.7 0.56 10.0 0.1 2.3 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit SMC_N PF02463.19 CDJ38282.1 - 1.7e-15 57.0 21.0 3.5e-15 56.0 21.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ38282.1 - 5.5e-10 39.6 2.2 9.7e-10 38.7 0.2 2.5 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system UPF0164 PF03687.13 CDJ38282.1 - 0.15 10.8 0.2 0.39 9.5 0.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0164) p25-alpha PF05517.12 CDJ38283.1 - 1.3e-36 126.2 3.4 1.4e-36 126.0 3.4 1.0 1 0 0 1 1 1 1 p25-alpha SurA_N PF09312.11 CDJ38283.1 - 0.03 14.4 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain SMYLE_N PF18615.1 CDJ38284.1 - 0.81 9.2 20.5 1.5 8.3 20.5 1.4 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DSHCT PF08148.12 CDJ38285.1 - 4.7e-40 136.9 0.3 1.3e-39 135.5 0.1 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 CDJ38285.1 - 7.3e-07 29.4 0.1 1.3e-06 28.6 0.1 1.5 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 CDJ38285.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain RVT_1 PF00078.27 CDJ38287.1 - 0.00015 21.4 0.0 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ38288.1 - 2.8e-07 31.1 0.0 4.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ38288.1 - 1.1e-06 29.1 0.0 1.7e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ38288.1 - 0.0012 18.6 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CDJ38288.1 - 0.027 14.8 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 CDJ38289.1 - 1.3e-08 34.5 14.1 1.3e-06 28.2 2.8 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ38289.1 - 0.0052 16.7 2.2 0.0052 16.7 2.2 2.5 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ38289.1 - 0.0083 15.9 10.3 0.0096 15.7 1.6 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ38289.1 - 0.0095 15.7 4.3 0.24 11.1 0.3 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ38289.1 - 0.015 15.1 1.1 0.015 15.1 1.1 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ38289.1 - 0.21 11.3 11.2 2.4 8.0 0.7 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DnaJ_CXXCXGXG PF00684.19 CDJ38289.1 - 0.24 11.8 10.3 0.82 10.1 10.1 2.0 1 1 1 2 2 2 0 DnaJ central domain Piezo_RRas_bdg PF12166.8 CDJ38292.1 - 0.057 12.7 0.9 0.42 9.8 0.0 2.1 2 0 0 2 2 2 0 Piezo non-specific cation channel, R-Ras-binding domain DUF3853 PF12964.7 CDJ38292.1 - 0.079 13.1 0.9 0.079 13.1 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) DUF572 PF04502.13 CDJ38292.1 - 0.26 10.9 13.9 0.54 9.8 13.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Gemini_mov PF01708.16 CDJ38292.1 - 1.1 9.1 0.0 1.1 9.1 0.0 3.0 3 0 0 3 3 3 0 Geminivirus putative movement protein Conotoxin PF02950.17 CDJ38292.1 - 1.2 10.1 0.1 1.2 10.1 0.1 4.6 4 2 0 4 4 4 0 Conotoxin DUF966 PF06136.13 CDJ38292.1 - 5.2 6.7 16.4 41 3.7 4.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF966) BAF1_ABF1 PF04684.13 CDJ38292.1 - 9.1 5.2 16.2 10 5.0 0.2 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF3597 PF12200.8 CDJ38293.1 - 2 8.9 7.5 3.4 8.2 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) DUF3138 PF11336.8 CDJ38293.1 - 4.5 5.8 10.7 4.6 5.8 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4112 PF13430.6 CDJ38294.1 - 0.076 13.3 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) Otopetrin PF03189.13 CDJ38294.1 - 0.4 9.4 0.0 0.4 9.4 0.0 4.7 3 2 1 4 4 4 0 Otopetrin Peptidase_M41 PF01434.18 CDJ38295.1 - 1.2e-48 165.5 0.0 2.2e-48 164.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CDJ38295.1 - 3.5e-40 137.5 0.0 1e-39 136.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ38295.1 - 1.2e-10 41.0 0.1 3e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDJ38295.1 - 6.5e-08 33.1 6.2 0.00014 22.3 0.1 4.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CDJ38295.1 - 1.6e-05 25.2 0.5 0.0055 17.0 0.0 3.2 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 CDJ38295.1 - 1.8e-05 24.5 0.0 5.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ38295.1 - 4.1e-05 23.6 0.0 0.00015 21.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CDJ38295.1 - 0.0002 20.7 0.0 0.00033 20.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 CDJ38295.1 - 0.0041 16.3 0.0 0.0075 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CDJ38295.1 - 0.0052 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 CDJ38295.1 - 0.0067 16.6 0.3 0.023 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CDJ38295.1 - 0.017 15.4 0.5 0.044 14.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 CDJ38295.1 - 0.02 14.8 0.7 0.074 13.0 0.0 2.3 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 CDJ38295.1 - 0.033 14.7 0.0 0.1 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CDJ38295.1 - 0.042 13.2 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CDJ38295.1 - 0.058 12.7 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 CDJ38295.1 - 0.062 12.8 0.0 0.18 11.3 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_2 PF07724.14 CDJ38295.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 CDJ38295.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 CDJ38295.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CDJ38295.1 - 0.19 11.1 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NAPRTase_C PF17956.1 CDJ38295.1 - 0.22 12.0 0.9 0.52 10.8 0.9 1.5 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain Abhydrolase_6 PF12697.7 CDJ38296.1 - 6.4e-15 56.4 3.3 6.4e-15 56.4 3.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ38296.1 - 4.1e-11 43.0 1.0 2.2e-09 37.3 1.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ38296.1 - 1.6e-05 24.3 0.0 4.4e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CDJ38296.1 - 1.7e-05 25.1 0.4 2.6e-05 24.5 0.4 1.4 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 CDJ38296.1 - 0.00013 20.8 0.2 0.42 9.3 0.4 2.2 2 0 0 2 2 2 2 Ndr family PGAP1 PF07819.13 CDJ38296.1 - 0.01 15.6 0.1 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein Chlorophyllase2 PF12740.7 CDJ38296.1 - 0.076 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 CDJ38296.1 - 0.13 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) BRAP2 PF07576.12 CDJ38297.1 - 0.13 12.5 0.0 0.77 10.0 0.0 2.1 2 0 0 2 2 2 0 BRCA1-associated protein 2 CPSase_L_D3 PF02787.19 CDJ38297.1 - 0.14 12.5 1.3 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Complex1_LYR_2 PF13233.6 CDJ38297.1 - 2 9.2 4.3 0.76 10.6 0.2 2.4 3 0 0 3 3 3 0 Complex1_LYR-like PAPS_reduct PF01507.19 CDJ38299.1 - 4.5e-21 75.6 3.4 5.8e-13 49.3 0.0 3.7 2 1 1 3 3 3 2 Phosphoadenosine phosphosulfate reductase family TFIIA PF03153.13 CDJ38299.1 - 0.011 15.8 59.4 0.029 14.4 30.4 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Scs3p PF10261.9 CDJ38299.1 - 0.023 14.2 0.0 0.05 13.1 0.0 1.6 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Peptidase_S15 PF02129.18 CDJ38299.1 - 7.8 6.0 18.9 3 7.4 8.9 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2828 PF11443.8 CDJ38299.1 - 8.7 4.3 27.0 1.3 7.1 15.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Suf PF05843.14 CDJ38300.1 - 0.12 12.3 3.4 0.18 11.8 3.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ38300.1 - 4.7 7.1 18.5 0.18 11.8 13.2 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Myosin_head PF00063.21 CDJ38302.1 - 2e-178 594.8 3.4 6.8e-159 530.2 3.5 2.2 1 1 1 2 2 2 2 Myosin head (motor domain) IQ PF00612.27 CDJ38302.1 - 7.3e-20 68.9 42.5 7.2e-05 22.2 0.2 7.7 8 0 0 8 8 8 6 IQ calmodulin-binding motif AAA_16 PF13191.6 CDJ38302.1 - 0.004 17.5 0.1 0.034 14.5 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain Myosin_N PF02736.19 CDJ38302.1 - 0.0059 16.4 0.2 0.013 15.3 0.2 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CDJ38302.1 - 0.016 15.4 0.0 0.052 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 CDJ38302.1 - 0.028 14.5 0.0 0.16 12.0 0.0 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sigma54_activat PF00158.26 CDJ38302.1 - 0.049 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 CDJ38302.1 - 0.075 12.8 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain KorB PF08535.10 CDJ38302.1 - 0.099 12.7 0.1 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 KorB domain RTC_insert PF05189.13 CDJ38303.1 - 0.1 13.1 0.0 0.1 13.1 0.0 2.7 2 1 0 2 2 2 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain Eapp_C PF10238.9 CDJ38304.1 - 0.0035 17.4 9.4 0.0041 17.2 9.4 1.0 1 0 0 1 1 1 1 E2F-associated phosphoprotein TRAP_alpha PF03896.16 CDJ38304.1 - 0.019 14.2 2.7 0.018 14.2 2.7 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DDRGK PF09756.9 CDJ38304.1 - 0.026 14.1 11.9 0.024 14.3 11.9 1.1 1 0 0 1 1 1 0 DDRGK domain Lipase_GDSL PF00657.22 CDJ38304.1 - 0.028 14.4 3.4 0.031 14.2 3.4 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF4746 PF15928.5 CDJ38304.1 - 0.048 13.1 4.8 0.049 13.0 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF5523 PF17661.1 CDJ38304.1 - 0.076 12.7 12.2 0.08 12.6 12.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RBM39linker PF15519.6 CDJ38304.1 - 0.085 13.9 10.2 0.11 13.6 10.2 1.1 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein CCDC53 PF10152.9 CDJ38304.1 - 0.13 12.6 10.0 0.13 12.7 10.0 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF719 PF05334.13 CDJ38304.1 - 0.13 12.4 7.5 0.13 12.4 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF719) FAM176 PF14851.6 CDJ38304.1 - 0.16 11.7 6.4 0.16 11.6 6.4 1.1 1 0 0 1 1 1 0 FAM176 family SpoIIP PF07454.11 CDJ38304.1 - 0.18 11.2 11.4 0.18 11.2 11.4 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CDJ38304.1 - 0.22 11.3 9.8 0.22 11.3 9.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 CDJ38304.1 - 0.23 10.2 9.5 0.24 10.1 9.5 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 CDJ38304.1 - 0.26 11.5 9.4 0.27 11.4 9.4 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Spt20 PF12090.8 CDJ38304.1 - 0.28 10.7 30.5 0.3 10.7 30.5 1.1 1 0 0 1 1 1 0 Spt20 family PTPRCAP PF15713.5 CDJ38304.1 - 0.3 11.3 13.4 0.3 11.4 13.4 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated EIIBC-GUT_N PF03612.14 CDJ38304.1 - 0.31 10.8 9.1 0.34 10.6 9.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus NARP1 PF12569.8 CDJ38304.1 - 0.32 9.9 10.6 0.31 9.9 10.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CobT PF06213.12 CDJ38304.1 - 0.33 10.3 17.3 0.37 10.2 17.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Suf PF05843.14 CDJ38304.1 - 0.36 10.8 14.2 0.34 10.9 14.2 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 CDJ38304.1 - 0.36 11.5 17.1 0.37 11.4 17.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4770 PF15994.5 CDJ38304.1 - 0.38 11.0 12.2 0.39 10.9 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Sec62 PF03839.16 CDJ38304.1 - 0.4 10.2 7.1 0.38 10.2 7.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S49_N PF08496.10 CDJ38304.1 - 0.4 10.7 7.5 0.42 10.7 7.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DDHD PF02862.17 CDJ38304.1 - 0.44 10.7 8.7 0.43 10.7 8.7 1.1 1 0 0 1 1 1 0 DDHD domain DUF3464 PF11947.8 CDJ38304.1 - 0.45 10.3 13.1 0.53 10.0 13.1 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Presenilin PF01080.17 CDJ38304.1 - 0.57 8.9 12.3 0.53 9.0 12.3 1.0 1 0 0 1 1 1 0 Presenilin PIP5K PF01504.18 CDJ38304.1 - 0.57 9.4 7.6 0.57 9.4 7.6 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF4834 PF16118.5 CDJ38304.1 - 0.58 11.2 14.2 0.73 10.8 14.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Connexin PF00029.19 CDJ38304.1 - 0.59 9.9 8.4 0.58 9.9 8.4 1.0 1 0 0 1 1 1 0 Connexin DUF2722 PF10846.8 CDJ38304.1 - 0.74 8.7 26.7 0.77 8.6 26.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Band_3_cyto PF07565.13 CDJ38304.1 - 0.77 9.5 9.4 0.83 9.4 9.4 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peroxin-13_N PF04088.13 CDJ38304.1 - 0.97 9.7 6.2 1.1 9.5 6.2 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region MDM31_MDM32 PF08118.11 CDJ38304.1 - 1 8.0 7.3 1.1 7.9 7.3 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Rxt3 PF08642.10 CDJ38304.1 - 1.1 10.0 5.9 1.2 9.9 5.9 1.1 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 EPL1 PF10513.9 CDJ38304.1 - 1.2 9.6 12.7 1.3 9.4 12.7 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like Orf78 PF06024.12 CDJ38304.1 - 1.2 9.5 5.9 1.5 9.2 5.9 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Gti1_Pac2 PF09729.9 CDJ38304.1 - 1.3 9.1 8.2 1.3 9.1 8.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family eIF-3_zeta PF05091.12 CDJ38304.1 - 1.3 7.9 15.1 1.3 7.9 15.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ38304.1 - 1.3 9.0 15.7 1.3 9.0 15.7 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Paf1 PF03985.13 CDJ38304.1 - 1.4 7.9 15.9 1.5 7.8 15.9 1.0 1 0 0 1 1 1 0 Paf1 OATP PF03137.20 CDJ38304.1 - 1.4 7.1 6.4 1.4 7.1 6.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ureide_permease PF07168.11 CDJ38304.1 - 1.5 7.5 4.0 1.5 7.5 4.0 1.0 1 0 0 1 1 1 0 Ureide permease Maf1 PF09174.10 CDJ38304.1 - 1.5 8.9 6.0 1.6 8.9 6.0 1.1 1 0 0 1 1 1 0 Maf1 regulator Ctr PF04145.15 CDJ38304.1 - 1.6 9.4 7.3 1.5 9.4 7.3 1.1 1 0 0 1 1 1 0 Ctr copper transporter family SID-1_RNA_chan PF13965.6 CDJ38304.1 - 1.6 7.1 4.6 1.6 7.0 4.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 V_ATPase_I PF01496.19 CDJ38304.1 - 1.7 6.5 11.4 1.6 6.5 11.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AIF_C PF14721.6 CDJ38304.1 - 1.7 9.0 9.1 2 8.8 9.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Folate_carrier PF01770.18 CDJ38304.1 - 2.3 6.8 6.7 2.3 6.8 6.7 1.0 1 0 0 1 1 1 0 Reduced folate carrier CSG2 PF16965.5 CDJ38304.1 - 2.4 7.0 6.0 2.3 7.1 6.0 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator CLN3 PF02487.17 CDJ38304.1 - 2.4 7.1 8.3 2.4 7.1 8.3 1.0 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 CDJ38304.1 - 2.5 6.9 8.0 2.5 6.8 8.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Phage_Gp23 PF10669.9 CDJ38304.1 - 2.5 8.5 7.9 2.8 8.3 7.9 1.0 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) TFIIA PF03153.13 CDJ38304.1 - 2.5 8.0 31.5 2.7 7.9 31.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM51 PF15345.6 CDJ38304.1 - 2.7 7.8 14.0 2.9 7.7 14.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 MTABC_N PF16185.5 CDJ38304.1 - 2.8 7.4 5.4 3.4 7.1 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region MDM10 PF12519.8 CDJ38304.1 - 3.2 6.5 8.7 3.1 6.6 8.7 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF3537 PF12056.8 CDJ38304.1 - 3.3 6.4 7.1 3.7 6.3 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) EOS1 PF12326.8 CDJ38304.1 - 3.4 7.5 5.0 3.6 7.5 5.0 1.1 1 0 0 1 1 1 0 N-glycosylation protein TFB6 PF17110.5 CDJ38304.1 - 3.7 7.3 8.3 4.2 7.1 8.3 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Neur_chan_memb PF02932.16 CDJ38304.1 - 3.7 7.5 9.6 3.9 7.5 9.6 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1980 PF09323.10 CDJ38304.1 - 4 7.3 7.5 4.2 7.3 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) UPF0560 PF10577.9 CDJ38304.1 - 4.5 5.6 17.7 4.9 5.5 17.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FHIPEP PF00771.20 CDJ38304.1 - 4.6 5.6 8.5 4.7 5.6 8.5 1.0 1 0 0 1 1 1 0 FHIPEP family Kei1 PF08552.11 CDJ38304.1 - 4.7 7.0 5.9 4.6 7.1 5.9 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Nucleoside_tran PF01733.18 CDJ38304.1 - 4.8 6.5 4.9 4.8 6.5 4.9 1.0 1 0 0 1 1 1 0 Nucleoside transporter Paramyxo_ncap PF00973.19 CDJ38304.1 - 5 5.9 6.9 4.3 6.1 6.9 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4407 PF14362.6 CDJ38304.1 - 5.1 6.4 11.4 4.7 6.5 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4175 PF13779.6 CDJ38304.1 - 5.3 4.8 27.2 5.1 4.9 27.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Folliculin PF11704.8 CDJ38304.1 - 5.5 6.8 9.1 5.5 6.8 9.1 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Plasmodium_Vir PF05795.11 CDJ38304.1 - 5.7 6.2 8.2 6.1 6.2 8.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Zip PF02535.22 CDJ38304.1 - 6.2 5.9 7.2 6.1 6.0 7.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SUIM_assoc PF16619.5 CDJ38305.1 - 0.0093 16.0 3.5 0.028 14.5 3.5 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ38305.1 - 0.079 12.6 5.5 0.12 11.9 5.5 1.3 1 0 0 1 1 1 0 Spt20 family LRV PF01816.17 CDJ38305.1 - 0.09 13.2 0.3 0.09 13.2 0.3 3.7 4 0 0 4 4 4 0 Leucine rich repeat variant DUF2722 PF10846.8 CDJ38305.1 - 0.53 9.2 4.5 0.79 8.6 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ38305.1 - 0.92 9.4 11.5 0.074 13.0 5.9 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HEAT PF02985.22 CDJ38305.1 - 1.3 9.5 5.6 7.7 7.1 0.1 4.7 5 0 0 5 5 5 0 HEAT repeat U3snoRNP10 PF12397.8 CDJ38305.1 - 1.7 9.0 5.2 8.7 6.7 0.0 3.7 2 1 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 VPS13 PF16908.5 CDJ38306.1 - 0.0018 18.1 0.2 0.0018 18.1 0.2 2.6 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal CAF1 PF04857.20 CDJ38307.1 - 3.7 6.6 11.2 3.2 6.8 0.0 2.4 2 0 0 2 2 2 0 CAF1 family ribonuclease PH_4 PF15404.6 CDJ38307.1 - 4.5 7.0 18.6 4.5 7.0 11.7 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain Spt20 PF12090.8 CDJ38308.1 - 1 8.9 10.7 1.3 8.6 10.7 1.1 1 0 0 1 1 1 0 Spt20 family Draxin PF15550.6 CDJ38308.1 - 1.2 8.9 4.1 0.59 10.0 2.0 1.5 1 1 1 2 2 2 0 Draxin TetR_C_35 PF18556.1 CDJ38309.1 - 0.11 12.7 1.1 0.37 11.0 0.1 2.1 2 0 0 2 2 2 0 Bacterial Tetracyclin repressor, C-terminal domain SUIM_assoc PF16619.5 CDJ38309.1 - 0.11 12.6 0.3 0.11 12.6 0.3 2.3 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ThrE PF06738.12 CDJ38309.1 - 2.3 7.5 6.9 3.6 6.9 6.9 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter PRMT5 PF05185.16 CDJ38310.1 - 2.4e-29 102.4 0.1 7.4e-14 52.0 0.0 2.7 2 0 0 2 2 2 2 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 CDJ38310.1 - 2e-22 79.6 0.3 2e-22 79.6 0.3 2.3 2 1 0 2 2 2 1 PRMT5 TIM barrel domain SR-25 PF10500.9 CDJ38310.1 - 0.00039 20.1 20.8 0.00039 20.1 20.8 5.4 6 0 0 6 6 6 2 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ38310.1 - 0.01 14.9 0.6 0.01 14.9 0.6 6.5 4 2 2 6 6 6 0 Protein of unknown function (DUF2722) RGCC PF15151.6 CDJ38310.1 - 9.3 6.5 12.0 0.49 10.6 3.9 2.8 2 0 0 2 2 2 0 Response gene to complement 32 protein family PIP5K PF01504.18 CDJ38312.1 - 1.3e-25 90.2 19.9 6.4e-23 81.4 15.3 3.6 1 1 1 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase SUIM_assoc PF16619.5 CDJ38313.1 - 0.1 12.7 12.6 0.29 11.2 3.0 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Miga PF10265.9 CDJ38313.1 - 0.48 9.3 5.8 0.7 8.8 5.8 1.1 1 0 0 1 1 1 0 Mitoguardin Spt20 PF12090.8 CDJ38313.1 - 6.5 6.3 10.1 1.7 8.2 4.6 2.1 2 0 0 2 2 2 0 Spt20 family Spt20 PF12090.8 CDJ38314.1 - 0.005 16.5 1.2 0.0065 16.1 1.2 1.1 1 0 0 1 1 1 1 Spt20 family Cyt_bd_oxida_II PF02322.15 CDJ38314.1 - 0.039 13.3 16.0 0.13 11.6 7.6 2.1 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II SUIM_assoc PF16619.5 CDJ38314.1 - 2.9 8.0 13.0 0.06 13.4 5.8 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ38314.1 - 4.7 7.1 11.4 6.3 6.7 11.4 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit La PF05383.17 CDJ38315.1 - 4.5e-12 45.8 0.0 9.7e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 La domain DUF3223 PF11523.8 CDJ38315.1 - 1.2e-11 45.3 0.1 2.4e-05 25.1 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3223) FAM60A PF15396.6 CDJ38315.1 - 3 7.8 6.2 7.6 6.5 6.2 1.7 1 0 0 1 1 1 0 Protein Family FAM60A Roughex PF06020.11 CDJ38315.1 - 7.1 5.6 15.6 14 4.6 15.6 1.5 1 0 0 1 1 1 0 Drosophila roughex protein FHA PF00498.26 CDJ38316.1 - 7.2e-10 39.1 0.1 1.3e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 FHA domain zf-C3HC4_4 PF15227.6 CDJ38316.1 - 4.7e-07 29.8 14.2 1.5e-06 28.2 14.2 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CDJ38316.1 - 7.1e-07 29.1 12.8 1.3e-06 28.3 10.9 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ38316.1 - 8.2e-05 22.4 13.1 0.00016 21.5 13.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ38316.1 - 0.00011 22.0 15.9 0.00023 20.9 15.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ38316.1 - 0.00012 22.3 16.3 0.00032 21.0 16.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ38316.1 - 0.00029 20.6 16.0 0.00063 19.6 16.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ38316.1 - 0.0014 18.6 15.0 0.0034 17.3 15.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain U-box PF04564.15 CDJ38316.1 - 0.006 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_10 PF16685.5 CDJ38316.1 - 0.028 14.6 12.1 0.073 13.2 12.1 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 CDJ38316.1 - 0.06 13.2 16.2 0.54 10.2 16.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CDJ38316.1 - 4.4 7.2 12.7 15 5.5 12.8 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain SR-25 PF10500.9 CDJ38316.1 - 7.5 6.1 22.2 5.5 6.5 14.1 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein C12orf66_like PF09404.10 CDJ38317.1 - 0.03 13.2 0.6 0.043 12.7 0.6 1.1 1 0 0 1 1 1 0 KICSTOR complex C12orf66 like ParB PF08775.10 CDJ38317.1 - 0.067 13.7 9.5 0.37 11.3 1.2 2.3 1 1 1 2 2 2 0 ParB family DUF4055 PF13264.6 CDJ38317.1 - 0.15 12.2 2.7 0.14 12.3 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) DUF87 PF01935.17 CDJ38317.1 - 0.24 11.4 4.0 0.31 11.1 3.1 1.5 1 1 0 1 1 1 0 Helicase HerA, central domain DASH_Dad2 PF08654.10 CDJ38317.1 - 2.6 8.5 8.3 6 7.3 0.2 3.0 2 1 1 3 3 3 0 DASH complex subunit Dad2 DNA_photolyase PF00875.18 CDJ38317.1 - 2.6 8.0 7.0 1.4 8.9 0.5 3.1 1 1 2 3 3 3 0 DNA photolyase RRM_1 PF00076.22 CDJ38318.1 - 4e-22 77.8 0.0 5.4e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ38318.1 - 4.6e-08 33.1 0.0 0.015 15.4 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif D123 PF07065.14 CDJ38319.1 - 1.5e-16 60.4 0.0 1.4e-10 40.9 0.0 4.5 4 1 0 4 4 4 2 D123 TFIIA PF03153.13 CDJ38319.1 - 0.26 11.2 59.6 0.11 12.5 6.7 4.1 3 1 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit CAF1 PF04857.20 CDJ38319.1 - 1.3 8.1 4.6 1.2 8.2 0.6 2.2 2 0 0 2 2 2 0 CAF1 family ribonuclease EPL1 PF10513.9 CDJ38319.1 - 1.7 9.0 12.2 0.99 9.8 0.1 3.5 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF3464 PF11947.8 CDJ38319.1 - 2.3 7.9 6.3 2.7 7.7 0.3 3.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 EamA PF00892.20 CDJ38320.1 - 3.2e-07 30.6 38.9 1.7e-05 25.0 13.7 3.5 3 0 0 3 3 3 3 EamA-like transporter family His_Phos_2 PF00328.22 CDJ38322.1 - 2.4e-45 155.5 11.3 1.2e-26 94.0 0.2 5.5 5 0 0 5 5 5 5 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CDJ38322.1 - 2.6e-33 114.0 0.0 4.9e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain HEAT PF02985.22 CDJ38323.1 - 1.6e-12 46.6 10.4 0.0038 17.3 0.0 5.7 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 CDJ38323.1 - 9.9e-09 35.5 19.8 2.1e-06 28.0 0.5 5.9 5 0 0 5 5 5 2 HEAT repeats Pkinase PF00069.25 CDJ38323.1 - 6.3e-06 25.7 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 CDJ38323.1 - 2.4e-05 24.4 0.0 0.079 13.0 0.0 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CDJ38323.1 - 0.074 13.6 0.0 0.074 13.6 0.0 9.6 10 1 1 11 11 11 0 HEAT-like repeat WD40 PF00400.32 CDJ38323.1 - 0.1 13.5 0.9 0.52 11.3 0.1 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat SpoIIIAH PF12685.7 CDJ38323.1 - 0.2 11.4 0.0 0.2 11.4 0.0 5.1 5 1 0 5 5 5 0 SpoIIIAH-like protein SPX PF03105.19 CDJ38323.1 - 0.9 9.4 32.0 0.35 10.7 7.7 4.4 4 0 0 4 4 4 0 SPX domain AP2 PF00847.20 CDJ38324.1 - 0.0022 18.2 8.7 0.088 13.0 0.6 2.5 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.6 CDJ38326.1 - 6.4e-09 36.0 0.0 0.00016 21.9 0.0 3.1 3 0 0 3 3 3 2 AP2-coincident C-terminal CdvA PF18822.1 CDJ38327.1 - 0.17 11.7 1.7 0.34 10.7 1.7 1.4 1 0 0 1 1 1 0 CdvA-like coiled-coil domain TFIIA PF03153.13 CDJ38327.1 - 0.19 11.7 29.4 1.1 9.1 4.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF444 PF04285.12 CDJ38327.1 - 1.3 8.0 6.8 0.11 11.6 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF444) DUF4094 PF13334.6 CDJ38327.1 - 2.7 8.5 5.8 0.28 11.6 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) DUF2203 PF09969.9 CDJ38327.1 - 3.9 8.2 6.4 0.63 10.8 0.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) CLPTM1 PF05602.12 CDJ38328.1 - 1.6e-27 96.7 0.0 7.7e-26 91.1 0.0 2.5 2 1 0 2 2 2 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) AMO PF02461.16 CDJ38328.1 - 0.0079 16.0 0.8 0.0079 16.0 0.8 1.9 2 0 0 2 2 2 1 Ammonia monooxygenase DUF3402 PF11882.8 CDJ38329.1 - 0.053 12.6 0.5 0.085 11.9 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3402) RseA_C PF03873.13 CDJ38329.1 - 1.6 9.0 12.6 3.1 8.1 0.6 3.4 3 1 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain PqqD PF05402.12 CDJ38330.1 - 0.59 10.5 4.4 2.2 8.7 2.1 3.3 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) SGT1 PF07093.11 CDJ38332.1 - 0.00087 17.8 0.2 0.0023 16.4 0.2 1.6 1 0 0 1 1 1 1 SGT1 protein HATPase_c_3 PF13589.6 CDJ38334.1 - 8.4e-05 22.4 0.0 0.00014 21.7 0.0 1.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ38334.1 - 0.0059 17.1 0.0 0.0088 16.5 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase XPA_N PF01286.18 CDJ38334.1 - 0.11 12.5 0.2 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 XPA protein N-terminal Pkinase PF00069.25 CDJ38336.1 - 2.5e-17 63.1 0.0 2.5e-17 63.1 0.0 3.9 3 2 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ38336.1 - 6.8e-09 35.4 0.0 2e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase LMWPc PF01451.21 CDJ38338.1 - 1.7e-24 86.8 0.0 2.3e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Ribosomal_S9 PF00380.19 CDJ38339.1 - 1.2e-18 67.8 0.1 1.4e-18 67.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.18 CDJ38340.1 - 1.9e-72 242.9 6.0 7.1e-72 241.0 6.0 2.1 1 0 0 1 1 1 1 Ribosomal protein L13e CENP-Q PF13094.6 CDJ38340.1 - 0.0046 17.2 5.0 0.0046 17.2 5.0 5.2 5 1 1 6 6 6 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF2730 PF10805.8 CDJ38340.1 - 0.01 15.9 9.5 0.22 11.6 0.7 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF5082 PF16888.5 CDJ38340.1 - 0.081 13.2 11.7 0.049 13.9 2.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) betaPIX_CC PF16523.5 CDJ38340.1 - 0.098 12.5 8.6 0.37 10.6 6.9 2.9 2 0 0 2 2 2 0 betaPIX coiled coil FapA PF03961.13 CDJ38340.1 - 0.55 8.8 8.9 4.4 5.8 0.0 3.2 3 0 0 3 3 3 0 Flagellar Assembly Protein A COG7 PF10191.9 CDJ38340.1 - 2.2 6.4 6.4 0.27 9.4 1.4 1.8 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) DUF4407 PF14362.6 CDJ38340.1 - 2.7 7.3 24.6 0.24 10.7 2.8 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4407) DUF1043 PF06295.12 CDJ38340.1 - 7.9 6.5 6.5 47 4.0 0.9 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) zf-CCCH PF00642.24 CDJ38341.1 - 2.1e-06 27.5 15.2 0.019 14.9 0.5 3.8 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ38341.1 - 1.8e-05 24.4 7.4 0.0038 17.0 0.8 3.5 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_5 PF18384.1 CDJ38341.1 - 0.018 15.1 2.9 2.8 8.1 0.9 3.0 2 0 0 2 2 2 0 Unkempt Zinc finger domain 1 (Znf1) zf_CCCH_4 PF18345.1 CDJ38341.1 - 0.092 12.8 15.5 0.25 11.5 0.4 4.3 3 1 0 3 3 3 0 Zinc finger domain DUF3568 PF12092.8 CDJ38342.1 - 0.089 12.9 1.0 0.76 9.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) DUF4335 PF14233.6 CDJ38342.1 - 0.27 11.1 2.1 1.1 9.2 2.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) RNA_polI_A14 PF08203.11 CDJ38342.1 - 1.7 9.4 5.4 1.3 9.8 0.3 3.7 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 CRAL_TRIO PF00650.20 CDJ38345.1 - 1.8e-31 109.0 0.0 2.5e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ38345.1 - 5.2e-06 26.7 0.1 8.6e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CDJ38345.1 - 0.0039 17.3 1.7 0.0064 16.7 0.3 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DnaJ PF00226.31 CDJ38346.1 - 4.2e-17 62.0 8.8 7.4e-17 61.2 2.2 3.8 3 1 0 3 3 3 1 DnaJ domain Myb_DNA-binding PF00249.31 CDJ38346.1 - 3e-16 59.3 0.3 1.3e-08 34.9 0.1 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ38346.1 - 2.1e-05 24.7 0.2 0.0048 17.1 0.0 4.2 5 0 0 5 5 5 2 Myb-like DNA-binding domain Exonuc_VII_L PF02601.15 CDJ38346.1 - 0.0017 18.0 1.1 0.0017 18.0 1.1 2.6 2 1 0 2 2 2 1 Exonuclease VII, large subunit FAM60A PF15396.6 CDJ38346.1 - 0.0036 17.3 0.9 0.0036 17.3 0.9 3.9 3 2 1 4 4 4 1 Protein Family FAM60A FancD2 PF14631.6 CDJ38346.1 - 1 6.7 11.2 2.2 5.6 11.2 1.5 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease HeLo PF14479.6 CDJ38346.1 - 1.4 8.7 19.4 2.2 8.1 14.5 2.8 2 0 0 2 2 2 0 Prion-inhibition and propagation GvpL_GvpF PF06386.11 CDJ38346.1 - 3.2 7.6 25.3 0.86 9.5 3.7 2.5 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF SAP PF02037.27 CDJ38347.1 - 5.7e-07 29.2 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 SAP domain zinc_ribbon_6 PF14599.6 CDJ38348.1 - 5e-22 77.7 1.7 5e-22 77.7 1.7 4.1 4 1 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 CDJ38348.1 - 4.3e-18 65.6 20.6 4.3e-18 65.6 20.6 4.3 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 CDJ38348.1 - 1.7e-07 31.5 5.0 1.7e-07 31.5 5.0 5.7 4 1 1 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ38348.1 - 3e-07 30.4 3.0 3e-07 30.4 3.0 4.4 4 2 0 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ38348.1 - 4.8e-05 23.2 7.5 4.8e-05 23.2 7.5 6.0 4 2 1 5 5 5 2 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ38348.1 - 0.00016 21.4 6.2 0.00016 21.4 6.2 5.6 2 1 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ38348.1 - 0.0026 17.5 2.2 0.0026 17.5 2.2 4.8 7 0 0 7 7 7 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CDJ38348.1 - 0.0032 17.6 2.1 0.0032 17.6 2.1 5.3 5 2 0 5 5 5 1 zinc finger of C3HC4-type, RING GcpE PF04551.14 CDJ38348.1 - 3.6 6.6 5.2 1.1 8.3 0.2 1.9 1 1 0 2 2 2 0 GcpE protein PA PF02225.22 CDJ38349.1 - 1e-06 28.7 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 PA domain Myb_DNA-bind_7 PF15963.5 CDJ38351.1 - 1.3e-21 76.2 0.1 1.3e-21 76.2 0.1 2.2 2 0 0 2 2 2 1 Myb DNA-binding like HMG_box_2 PF09011.10 CDJ38351.1 - 6.3e-10 39.5 1.4 3e-05 24.5 0.2 2.8 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 CDJ38351.1 - 1.7e-07 31.6 0.2 0.00034 21.0 0.1 2.8 2 0 0 2 2 2 2 HMG (high mobility group) box Myb_DNA-binding PF00249.31 CDJ38351.1 - 0.025 14.8 0.2 0.088 13.0 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Methyltrn_RNA_4 PF09936.9 CDJ38351.1 - 0.043 13.7 0.7 0.17 11.8 0.7 2.0 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase DUF1400 PF07176.11 CDJ38353.1 - 0.17 12.1 3.8 1.1 9.5 0.5 3.0 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF1400) Flg_hook PF02120.16 CDJ38353.1 - 0.96 9.4 6.4 0.71 9.8 0.5 3.4 3 1 1 4 4 4 0 Flagellar hook-length control protein FliK Troponin PF00992.20 CDJ38353.1 - 1.5 9.1 10.0 0.19 12.1 5.0 2.0 2 0 0 2 2 2 0 Troponin RabGAP-TBC PF00566.18 CDJ38354.1 - 8.9e-44 149.7 0.4 1.4e-43 149.1 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain YabA PF06156.13 CDJ38354.1 - 0.056 14.1 0.7 0.16 12.7 0.7 1.7 1 0 0 1 1 1 0 Initiation control protein YabA Wbp11 PF09429.10 CDJ38356.1 - 1.9e-14 53.8 7.1 2.2e-14 53.6 7.1 1.1 1 0 0 1 1 1 1 WW domain binding protein 11 120_Rick_ant PF12574.8 CDJ38356.1 - 0.045 13.0 0.2 0.05 12.8 0.2 1.0 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen MCM_bind PF09739.9 CDJ38357.1 - 0.083 11.3 1.7 0.15 10.5 1.7 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Dynein_light PF01221.18 CDJ38359.1 - 4.9e-06 26.8 0.1 7.1e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3273 PF11677.8 CDJ38360.1 - 4.1e-98 327.9 7.8 4.6e-98 327.7 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF3273 PF11677.8 CDJ38361.1 - 8.3e-100 333.5 7.5 9.5e-100 333.3 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) VWA PF00092.28 CDJ38362.1 - 2.8e-34 118.9 0.0 3.8e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.19 CDJ38362.1 - 3.6e-26 91.1 71.9 1.5e-07 31.5 3.7 7.1 6 1 0 6 6 6 6 Thrombospondin type 1 domain VWA_2 PF13519.6 CDJ38362.1 - 9.9e-16 58.3 0.0 1.9e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain OTU PF02338.19 CDJ38363.1 - 1.7e-09 38.3 0.0 4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDJ38363.1 - 6.5e-05 22.5 0.1 0.0071 15.8 0.1 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain DUF2012 PF09430.10 CDJ38364.1 - 2.6e-10 40.5 0.0 4.3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Anticodon_1 PF08264.13 CDJ38365.1 - 4.6e-20 72.1 0.0 6.8e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.14 CDJ38365.1 - 0.18 11.7 4.7 0.15 12.0 0.6 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS tRNA-synt_1 PF00133.22 CDJ38366.1 - 4.5e-77 259.7 0.0 4.2e-37 127.7 0.0 5.4 5 1 0 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CDJ38366.1 - 9.4e-09 34.5 0.3 1.4e-05 24.1 0.0 3.7 4 0 0 4 4 4 2 tRNA synthetases class I (M) WD40 PF00400.32 CDJ38367.1 - 1.2e-44 149.3 30.7 1.6e-09 38.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ38367.1 - 3.7e-11 43.2 2.9 0.088 13.1 0.0 4.9 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDJ38367.1 - 1.1e-07 31.6 0.0 0.00016 21.1 0.0 2.6 2 1 1 3 3 3 3 WD40-like domain PQQ_3 PF13570.6 CDJ38367.1 - 0.00049 20.5 0.9 0.079 13.5 0.0 3.7 3 1 0 3 3 3 1 PQQ-like domain Nup160 PF11715.8 CDJ38367.1 - 0.003 16.3 16.7 0.094 11.3 0.4 5.0 1 1 3 5 5 5 3 Nucleoporin Nup120/160 Adeno_terminal PF02459.15 CDJ38367.1 - 0.081 11.3 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Citrate_synt PF00285.21 CDJ38368.1 - 6e-70 236.1 0.0 4.2e-34 118.2 0.1 2.0 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Pox_G5 PF04599.12 CDJ38368.1 - 0.28 10.2 0.0 0.4 9.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein IHABP4_N PF16174.5 CDJ38369.1 - 0.019 15.6 2.1 0.019 15.6 2.1 3.5 2 1 1 3 3 3 0 Intracellular hyaluronan-binding protein 4 N-terminal TauE PF01925.19 CDJ38370.1 - 8.9e-24 84.4 21.2 4.6e-11 42.8 17.9 2.1 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DUF4328 PF14219.6 CDJ38370.1 - 0.012 15.1 0.2 0.035 13.7 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF1127 PF06568.11 CDJ38370.1 - 0.16 11.7 3.1 0.65 9.8 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) Presenilin PF01080.17 CDJ38370.1 - 0.47 9.2 5.4 1 8.1 5.4 1.5 1 0 0 1 1 1 0 Presenilin DUF2938 PF11158.8 CDJ38371.1 - 0.0081 15.6 1.2 0.014 14.9 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2938) SAC3_GANP PF03399.16 CDJ38372.1 - 1e-28 100.6 0.0 1e-28 100.6 0.0 3.9 3 1 0 3 3 3 1 SAC3/GANP family Amidase PF01425.21 CDJ38373.1 - 5.5e-05 22.3 0.7 0.023 13.7 0.0 3.0 4 0 0 4 4 4 2 Amidase DUF1298 PF06974.13 CDJ38373.1 - 0.0046 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) FTHFS PF01268.19 CDJ38373.1 - 0.18 10.0 0.1 0.26 9.4 0.1 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Guanylate_cyc PF00211.20 CDJ38374.1 - 9.1e-82 273.1 0.4 2e-43 148.2 0.1 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 CDJ38374.1 - 2.8e-53 181.2 21.7 2.8e-53 181.2 21.7 4.5 4 1 1 5 5 5 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 CDJ38374.1 - 5.6e-07 30.1 0.0 0.021 15.1 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ38374.1 - 1.2e-05 25.8 0.1 0.011 16.2 0.0 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ38374.1 - 2.4e-05 24.2 0.0 0.00053 19.8 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1053 PF06327.14 CDJ38374.1 - 0.18 12.4 0.9 8.2 7.0 0.2 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) Abhydrolase_9_N PF15420.6 CDJ38374.1 - 1 9.4 9.4 0.26 11.2 1.2 2.8 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus PhoLip_ATPase_N PF16209.5 CDJ38375.1 - 5.7e-16 58.0 0.4 1.7e-15 56.5 0.0 1.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CDJ38375.1 - 6.8e-08 32.2 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Vps55 PF04133.14 CDJ38375.1 - 0.098 12.6 0.2 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 55 Aminotran_4 PF01063.19 CDJ38378.1 - 4.6e-12 46.3 0.0 9.8e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Amino-transferase class IV RNase_HII PF01351.18 CDJ38379.1 - 1e-50 172.3 0.0 3e-46 157.8 0.1 2.2 2 0 0 2 2 2 2 Ribonuclease HII PASTA PF03793.19 CDJ38379.1 - 0.091 12.6 0.1 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 PASTA domain Pkinase PF00069.25 CDJ38380.1 - 7.8e-65 218.9 0.0 9.8e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ38380.1 - 4.2e-30 104.9 0.0 5.4e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ38380.1 - 1.5e-05 24.5 0.0 7.6e-05 22.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ38380.1 - 0.00015 21.2 0.2 0.00055 19.3 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ38380.1 - 0.00096 18.0 0.1 0.0029 16.4 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ38380.1 - 0.0025 17.8 0.1 1.5 8.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Na_sulph_symp PF00939.19 CDJ38382.1 - 8.3e-30 104.2 11.0 3.5e-15 56.0 6.2 2.0 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CDJ38382.1 - 5.6e-17 61.9 57.6 5e-08 32.5 5.8 3.3 2 1 1 3 3 3 3 Citrate transporter HTH_32 PF13565.6 CDJ38383.1 - 0.18 12.5 7.4 0.88 10.2 1.3 2.5 2 1 0 2 2 2 0 Homeodomain-like domain Tmemb_9 PF05434.11 CDJ38383.1 - 0.66 9.9 4.4 0.24 11.3 0.4 2.1 2 0 0 2 2 2 0 TMEM9 KAsynt_C_assoc PF16197.5 CDJ38383.1 - 2.2 8.7 5.4 4.9 7.7 1.3 2.2 1 1 1 2 2 2 0 Ketoacyl-synthetase C-terminal extension CcmD PF04995.14 CDJ38383.1 - 4.1 7.6 13.3 1.7 8.8 1.0 3.3 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) AAA_12 PF13087.6 CDJ38386.1 - 2.1e-53 180.9 0.0 3.4e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain R3H PF01424.22 CDJ38386.1 - 3e-10 39.9 0.1 1.6e-09 37.6 0.1 2.3 2 0 0 2 2 2 1 R3H domain AAA_11 PF13086.6 CDJ38386.1 - 1.7e-08 34.6 0.1 1.7e-08 34.6 0.1 3.9 3 1 0 3 3 3 1 AAA domain zf-AN1 PF01428.16 CDJ38386.1 - 1.8e-08 34.4 4.4 3.3e-08 33.6 4.4 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Viral_helicase1 PF01443.18 CDJ38386.1 - 0.0078 16.0 0.0 0.048 13.4 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 CDJ38386.1 - 0.028 14.3 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain SPT6_acidic PF14632.6 CDJ38386.1 - 0.33 11.5 5.9 0.91 10.2 5.9 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 SRP54 PF00448.22 CDJ38387.1 - 2.8e-31 108.7 0.0 3.8e-25 88.7 0.0 2.6 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 CDJ38387.1 - 9e-12 45.5 7.5 9e-12 45.5 7.5 3.3 3 1 0 3 3 2 1 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.9 CDJ38387.1 - 0.011 14.3 21.1 0.0033 16.1 6.5 2.2 2 0 0 2 2 2 0 Macoilin family ETF PF01012.21 CDJ38387.1 - 0.017 15.0 0.2 0.017 15.0 0.2 2.3 2 0 0 2 2 2 0 Electron transfer flavoprotein domain AAA_22 PF13401.6 CDJ38387.1 - 0.031 14.5 2.7 0.29 11.4 0.0 3.3 3 1 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 CDJ38387.1 - 0.06 13.4 1.1 0.93 9.6 1.1 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Zip PF02535.22 CDJ38387.1 - 0.079 12.2 5.4 1.8 7.7 0.3 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter SUIM_assoc PF16619.5 CDJ38387.1 - 0.12 12.5 0.2 0.12 12.5 0.2 3.3 3 1 0 3 3 2 0 Unstructured region C-term to UIM in Ataxin3 NTPase_1 PF03266.15 CDJ38387.1 - 0.13 12.2 0.3 27 4.6 0.0 2.9 3 0 0 3 3 3 0 NTPase Apt1 PF10351.9 CDJ38387.1 - 1 8.1 23.2 0.095 11.5 10.8 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain AAA_17 PF13207.6 CDJ38387.1 - 1.2 9.6 4.4 3.8 8.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain Thymidylate_kin PF02223.17 CDJ38387.1 - 1.8 8.2 6.0 13 5.4 0.0 3.1 3 0 0 3 3 2 0 Thymidylate kinase ANAPC1 PF12859.7 CDJ38387.1 - 1.9 9.0 9.2 0.85 10.2 4.3 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Neur_chan_memb PF02932.16 CDJ38387.1 - 3.3 7.7 17.3 0.79 9.7 0.2 2.9 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region GvpL_GvpF PF06386.11 CDJ38387.1 - 5.1 7.0 8.6 0.24 11.3 1.8 2.2 2 1 1 3 3 3 0 Gas vesicle synthesis protein GvpL/GvpF 3HCDH_RFF PF18321.1 CDJ38387.1 - 7.1 7.2 8.7 14 6.2 0.1 3.5 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain BAF1_ABF1 PF04684.13 CDJ38387.1 - 10 5.1 16.3 11 5.0 9.0 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Cellulose_synt PF03552.14 CDJ38388.1 - 8.1 4.8 9.1 8.6 4.7 9.1 1.1 1 0 0 1 1 1 0 Cellulose synthase Pepdidase_M14_N PF18027.1 CDJ38389.1 - 0.01 16.2 0.1 0.029 14.7 0.0 1.9 2 0 0 2 2 2 0 Cytosolic carboxypeptidase N-terminal domain Utp14 PF04615.13 CDJ38389.1 - 0.13 10.9 28.0 0.18 10.3 28.0 1.2 1 0 0 1 1 1 0 Utp14 protein BAF1_ABF1 PF04684.13 CDJ38389.1 - 0.73 8.8 29.5 0.17 10.9 24.3 1.9 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Adeno_PIX PF03955.14 CDJ38389.1 - 6 7.1 14.5 14 5.9 14.5 1.6 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) RskA PF10099.9 CDJ38390.1 - 3.8 7.8 16.0 4.8 7.4 9.6 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF1822 PF08852.11 CDJ38391.1 - 0.0045 16.1 3.9 0.0051 15.9 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1822) DUF295 PF03478.18 CDJ38391.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF295) TFIIA PF03153.13 CDJ38391.1 - 1.6 8.6 13.5 1.9 8.4 13.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L18 PF17135.4 CDJ38394.1 - 8.9e-45 152.4 0.2 9.7e-45 152.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CDJ38394.1 - 0.019 15.6 0.0 0.032 14.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A CS PF04969.16 CDJ38395.1 - 1.4e-11 45.3 0.0 1.8e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 CS domain Ribosomal_L28e PF01778.17 CDJ38396.1 - 3.3e-28 98.8 1.1 3.3e-28 98.8 1.1 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family DUF3138 PF11336.8 CDJ38396.1 - 0.4 9.2 5.7 0.53 8.8 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RskA PF10099.9 CDJ38396.1 - 5.1 7.4 14.4 7.8 6.7 14.4 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CCDC24 PF15669.5 CDJ38399.1 - 0.017 15.0 0.1 0.019 14.9 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family IMUP PF15761.5 CDJ38399.1 - 4.3 8.1 9.7 5.3 7.8 9.7 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ38399.1 - 5.1 6.6 11.3 5.7 6.5 11.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ38400.1 - 0.012 15.2 26.8 0.018 14.6 26.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 CDJ38400.1 - 0.17 10.4 6.3 0.17 10.4 6.3 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ38400.1 - 0.33 9.8 7.9 0.37 9.6 7.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ38400.1 - 1 8.1 2.1 1.1 7.9 2.1 1.1 1 0 0 1 1 1 0 Presenilin CCDC106 PF15794.5 CDJ38400.1 - 1.4 8.6 13.0 1.9 8.1 13.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Ndc1_Nup PF09531.10 CDJ38401.1 - 0.078 11.7 7.4 0.1 11.2 7.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sin_N PF04801.13 CDJ38401.1 - 0.2 10.8 22.5 0.37 9.9 22.5 1.4 1 0 0 1 1 1 0 Sin-like protein conserved region JAMP PF05571.12 CDJ38402.1 - 0.04 13.5 9.4 0.087 12.4 3.1 2.1 1 1 1 2 2 2 0 JNK1/MAPK8-associated membrane protein EGF_CA PF07645.15 CDJ38402.1 - 0.066 13.4 9.6 0.14 12.3 9.6 1.6 1 0 0 1 1 1 0 Calcium-binding EGF domain DUF4027 PF13219.6 CDJ38402.1 - 9.2 6.2 8.0 8.6 6.3 6.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4027) BSP_II PF05432.11 CDJ38405.1 - 2.1 8.0 7.9 0.068 12.9 1.8 1.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Helicase_C PF00271.31 CDJ38406.1 - 2.1e-12 47.4 0.0 3.2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain INCA1 PF15142.6 CDJ38407.1 - 0.0065 16.5 1.8 0.0073 16.3 0.2 1.9 2 0 0 2 2 2 1 INCA1 Gelsolin PF00626.22 CDJ38407.1 - 0.33 10.9 1.5 0.8 9.7 1.5 1.6 1 0 0 1 1 1 0 Gelsolin repeat FAM101 PF15068.6 CDJ38409.1 - 0.0093 15.9 1.2 0.0093 15.9 1.2 2.4 3 0 0 3 3 3 1 FAM101 family EPL1 PF10513.9 CDJ38409.1 - 0.16 12.3 3.8 0.95 9.8 0.6 2.7 2 0 0 2 2 2 0 Enhancer of polycomb-like zf-CCHC PF00098.23 CDJ38410.1 - 1.9e-11 43.5 15.7 6e-05 22.9 0.6 3.2 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ38410.1 - 1.9e-06 27.7 17.7 8.9e-05 22.4 1.0 3.7 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ38410.1 - 3.7e-05 23.5 19.2 0.031 14.1 1.5 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ38410.1 - 0.053 13.3 14.1 0.52 10.1 1.2 3.1 3 0 0 3 3 3 0 Zinc knuckle DUF3716 PF12511.8 CDJ38410.1 - 0.11 12.6 11.2 0.3 11.2 6.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3716) zf-CCHC_5 PF14787.6 CDJ38410.1 - 0.14 11.8 19.6 1.4 8.7 4.5 3.2 2 1 1 3 3 3 0 GAG-polyprotein viral zinc-finger IBR PF01485.21 CDJ38410.1 - 8.9 6.6 13.5 16 5.8 0.5 3.3 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain PP2C PF00481.21 CDJ38411.1 - 5.8e-31 108.1 0.0 7.3e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ38411.1 - 0.0014 18.6 0.0 0.0044 17.0 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Sec63 PF02889.16 CDJ38412.1 - 6.5e-90 300.8 0.0 2.8e-45 154.5 0.0 2.6 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CDJ38412.1 - 5.9e-35 120.6 0.0 1.8e-22 79.9 0.0 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CDJ38412.1 - 1.2e-12 48.2 0.0 9.4e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ38412.1 - 1.3e-08 35.2 0.0 0.0061 16.9 0.0 3.9 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ38412.1 - 0.00015 22.1 8.9 0.0007 19.9 0.0 4.3 4 0 0 4 4 4 2 AAA domain MerC PF03203.14 CDJ38412.1 - 0.0041 17.6 1.4 0.0041 17.6 1.4 3.9 2 0 0 2 2 2 1 MerC mercury resistance protein Hydrolase_6 PF13344.6 CDJ38413.1 - 2.2e-21 75.9 0.0 5.5e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Pex14_N PF04695.13 CDJ38413.1 - 0.00052 20.7 40.6 0.04 14.6 29.0 2.5 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region SUIM_assoc PF16619.5 CDJ38413.1 - 0.0017 18.4 0.0 0.0017 18.4 0.0 6.3 3 2 1 4 4 1 1 Unstructured region C-term to UIM in Ataxin3 SpoIIIAH PF12685.7 CDJ38413.1 - 0.0051 16.7 14.0 0.028 14.2 5.3 2.2 2 0 0 2 2 2 2 SpoIIIAH-like protein BAF1_ABF1 PF04684.13 CDJ38413.1 - 0.006 15.7 12.4 0.0076 15.4 12.4 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Rrn6 PF10214.9 CDJ38413.1 - 0.0062 15.1 26.5 0.0098 14.5 26.5 1.3 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Hydrolase PF00702.26 CDJ38413.1 - 0.014 15.7 2.3 0.045 14.0 0.1 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 CDJ38413.1 - 0.015 14.9 0.0 0.015 14.9 0.0 3.2 3 0 0 3 3 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) CPSF100_C PF13299.6 CDJ38413.1 - 0.024 14.8 18.1 0.054 13.7 9.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PAT1 PF09770.9 CDJ38413.1 - 0.033 12.5 43.9 0.097 10.9 29.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 CDJ38413.1 - 0.038 12.8 29.6 0.13 11.1 20.6 2.1 2 0 0 2 2 2 0 Presenilin PNISR PF15996.5 CDJ38413.1 - 0.076 13.3 30.7 0.25 11.6 17.8 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR FAM76 PF16046.5 CDJ38413.1 - 0.082 12.2 17.3 0.024 14.0 9.8 2.2 2 0 0 2 2 2 0 FAM76 protein DUF913 PF06025.12 CDJ38413.1 - 0.1 11.6 16.2 0.13 11.2 10.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SPX PF03105.19 CDJ38413.1 - 0.23 11.4 17.2 0.35 10.7 17.2 1.3 1 0 0 1 1 1 0 SPX domain SpoIIP PF07454.11 CDJ38413.1 - 0.32 10.4 24.6 0.22 11.0 14.3 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Endostatin PF06482.11 CDJ38413.1 - 0.42 10.0 23.5 0.4 10.1 15.6 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin DUF2052 PF09747.9 CDJ38413.1 - 0.55 10.3 27.5 2.1 8.4 19.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Lin-8 PF03353.15 CDJ38413.1 - 0.69 9.4 32.5 0.42 10.1 19.4 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist PIP5K PF01504.18 CDJ38413.1 - 0.83 8.8 15.7 7.1 5.8 11.1 2.3 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase GREB1 PF15782.5 CDJ38413.1 - 1.2 6.2 18.6 1.7 5.6 18.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pox_Ag35 PF03286.14 CDJ38413.1 - 1.3 8.8 10.3 0.16 11.8 4.4 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF572 PF04502.13 CDJ38413.1 - 5.2 6.6 26.2 9.3 5.8 26.3 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF572) ALMT PF11744.8 CDJ38413.1 - 7.1 5.3 18.6 3.1 6.5 11.0 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter Ctr PF04145.15 CDJ38413.1 - 9.4 6.8 18.3 8 7.1 0.6 2.4 2 0 0 2 2 2 0 Ctr copper transporter family DUF4746 PF15928.5 CDJ38413.1 - 9.9 5.5 20.3 0.46 9.9 10.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Thioredoxin PF00085.20 CDJ38415.1 - 0.0063 16.5 0.0 0.0075 16.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin MtN3_slv PF03083.16 CDJ38416.1 - 5.5e-07 29.5 0.2 1e-06 28.7 0.2 1.4 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange DUF5429 PF17494.2 CDJ38416.1 - 0.018 15.1 1.0 0.039 14.0 1.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5429) MFS_MOT1 PF16983.5 CDJ38416.1 - 0.3 11.5 12.5 0.032 14.6 6.4 2.1 1 1 1 2 2 2 0 Molybdate transporter of MFS superfamily sCache_2 PF17200.4 CDJ38417.1 - 0.056 13.3 0.4 0.084 12.7 0.4 1.2 1 0 0 1 1 1 0 Single Cache domain 2 Spt20 PF12090.8 CDJ38417.1 - 0.31 10.6 6.3 0.47 10.0 6.3 1.3 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ38417.1 - 2.6 6.8 12.3 4.4 6.0 12.3 1.3 1 0 0 1 1 1 0 Androgen receptor FTZ PF03867.14 CDJ38418.1 - 0.029 13.9 8.3 0.038 13.5 8.3 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Asp-B-Hydro_N PF05279.11 CDJ38418.1 - 0.24 11.4 5.3 0.3 11.1 5.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TFIIA PF03153.13 CDJ38418.1 - 0.49 10.3 25.8 0.6 10.0 25.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ38418.1 - 0.87 8.3 10.2 1 8.0 10.2 1.0 1 0 0 1 1 1 0 Presenilin UPF0560 PF10577.9 CDJ38418.1 - 2.9 6.3 11.8 3.6 6.0 11.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SprA-related PF12118.8 CDJ38418.1 - 4 6.5 17.7 5 6.2 17.7 1.1 1 0 0 1 1 1 0 SprA-related family PAT1 PF09770.9 CDJ38418.1 - 5.8 5.0 19.9 7.1 4.8 19.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TPT PF03151.16 CDJ38419.1 - 7.8e-56 189.5 5.6 7.7e-54 183.0 5.6 2.0 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CDJ38419.1 - 2.5e-05 24.4 16.4 0.0046 17.1 4.5 3.2 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CDJ38419.1 - 0.00021 20.6 2.0 0.1 11.8 0.2 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter UAA PF08449.11 CDJ38419.1 - 0.019 14.2 3.8 1.6 7.9 0.1 2.1 1 1 0 2 2 2 0 UAA transporter family Peptidase_M55 PF04951.13 CDJ38420.1 - 0.23 10.8 1.7 5.4 6.3 0.0 3.0 3 0 0 3 3 3 0 D-aminopeptidase TFIIA PF03153.13 CDJ38420.1 - 0.51 10.3 3.8 0.82 9.6 3.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apc15p PF05841.11 CDJ38420.1 - 0.54 11.1 5.2 0.18 12.6 1.0 2.3 2 0 0 2 2 2 0 Apc15p protein Secretin_N_2 PF07655.13 CDJ38420.1 - 2.3 8.8 17.2 45 4.7 12.4 3.1 3 0 0 3 3 3 0 Secretin N-terminal domain Apt1 PF10351.9 CDJ38420.1 - 6.6 5.5 7.1 11 4.8 7.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SH3_15 PF18346.1 CDJ38421.1 - 0.97 9.8 2.5 27 5.2 0.3 2.5 2 1 0 2 2 2 0 Mind bomb SH3 repeat domain Citrate_bind PF16114.5 CDJ38422.1 - 4.5e-74 247.8 0.0 7.5e-74 247.1 0.0 1.3 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 CDJ38422.1 - 6.8e-22 78.0 0.0 1.4e-20 73.7 0.0 2.6 1 1 1 2 2 2 1 Citrate synthase, C-terminal domain CoA_binding PF02629.19 CDJ38422.1 - 1.5e-08 35.2 0.0 3.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 CDJ38422.1 - 3.3e-08 33.5 0.0 7.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase AlaDh_PNT_C PF01262.21 CDJ38422.1 - 0.077 12.3 0.2 0.14 11.4 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SUIM_assoc PF16619.5 CDJ38422.1 - 0.35 11.0 4.2 0.86 9.7 4.2 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 ACDC PF14733.6 CDJ38423.1 - 5.3e-08 33.1 0.1 9.7e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal DUF5396 PF17374.2 CDJ38423.1 - 0.0018 16.3 0.6 0.0022 15.9 0.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5396) AF-4 PF05110.13 CDJ38423.1 - 0.0093 14.1 1.7 0.0089 14.2 1.7 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein DUF515 PF04415.12 CDJ38423.1 - 2.9 6.2 6.3 3.8 5.8 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Ribosomal_60s PF00428.19 CDJ38423.1 - 8 7.1 9.0 8.6 7.0 6.9 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2722 PF10846.8 CDJ38425.1 - 0.0013 17.8 5.1 0.0013 17.8 5.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ38425.1 - 5.7 6.5 36.5 0.14 11.8 17.5 2.3 2 0 0 2 2 2 0 Spt20 family Sec62 PF03839.16 CDJ38426.1 - 2.4e-15 56.7 0.9 2.7e-15 56.5 0.9 1.0 1 0 0 1 1 1 1 Translocation protein Sec62 FA_desaturase PF00487.24 CDJ38426.1 - 0.0079 16.1 0.3 0.0086 15.9 0.3 1.0 1 0 0 1 1 1 1 Fatty acid desaturase OPT PF03169.15 CDJ38426.1 - 0.097 11.3 4.1 0.11 11.1 4.1 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein SUIM_assoc PF16619.5 CDJ38427.1 - 0.0054 16.8 0.8 0.012 15.7 0.8 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Ribosomal_S13_N PF08069.12 CDJ38428.1 - 9.2e-27 92.9 0.0 1.3e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain HTH_32 PF13565.6 CDJ38428.1 - 0.014 16.0 0.0 0.016 15.8 0.0 1.1 1 0 0 1 1 1 0 Homeodomain-like domain Ribosomal_S2 PF00318.20 CDJ38430.1 - 4.4e-28 98.0 2.6 8.9e-16 57.8 0.1 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 DUF4148 PF13663.6 CDJ38431.1 - 0.17 12.1 15.3 0.33 11.1 3.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) FliX PF10768.9 CDJ38431.1 - 0.76 10.3 6.8 0.25 11.9 1.1 2.6 3 0 0 3 3 3 0 Class II flagellar assembly regulator DUF3446 PF11928.8 CDJ38431.1 - 0.91 9.9 14.3 0.041 14.2 3.5 3.1 3 0 0 3 3 3 0 Early growth response N-terminal domain Ribosomal_60s PF00428.19 CDJ38431.1 - 3.7 8.2 23.4 0.16 12.6 2.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein V_ATPase_I PF01496.19 CDJ38432.1 - 3.9 5.3 8.8 4.3 5.1 8.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SOBP PF15279.6 CDJ38432.1 - 6.3 7.3 17.4 9.7 6.7 17.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein AAA_23 PF13476.6 CDJ38432.1 - 7.6 7.0 19.9 0.11 13.0 13.0 1.5 2 0 0 2 2 2 0 AAA domain Miga PF10265.9 CDJ38434.1 - 9.1 5.1 13.6 9.3 5.1 13.6 1.0 1 0 0 1 1 1 0 Mitoguardin HlyD_2 PF12700.7 CDJ38435.1 - 8.1 5.1 6.5 11 4.6 0.1 2.5 2 0 0 2 2 2 0 HlyD family secretion protein Lsr2 PF11774.8 CDJ38437.1 - 8.9 6.5 10.7 13 6.0 2.2 2.7 3 0 0 3 3 3 0 Lsr2 RskA PF10099.9 CDJ38438.1 - 0.0011 19.3 1.6 0.0011 19.3 1.6 3.0 1 1 1 2 2 2 1 Anti-sigma-K factor rskA DUF3619 PF12279.8 CDJ38438.1 - 0.02 15.3 5.0 0.02 15.3 5.0 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF3619) TFIIA PF03153.13 CDJ38438.1 - 0.078 13.0 14.0 0.094 12.7 14.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ38438.1 - 0.17 11.4 8.6 0.25 10.9 8.6 1.2 1 0 0 1 1 1 0 Spt20 family DUF2681 PF10883.8 CDJ38439.1 - 0.003 17.9 5.4 0.003 17.9 5.4 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF2681) DUF4834 PF16118.5 CDJ38439.1 - 0.045 14.7 2.1 0.045 14.7 2.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) SurE PF01975.17 CDJ38440.1 - 0.11 12.2 6.1 1.2 8.9 0.5 3.0 1 1 2 3 3 3 0 Survival protein SurE SWIB PF02201.18 CDJ38441.1 - 8.3e-15 54.4 0.0 1.4e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain Presenilin PF01080.17 CDJ38441.1 - 0.1 11.3 6.2 0.25 10.1 0.1 2.0 2 0 0 2 2 2 0 Presenilin Pap_E4 PF02711.14 CDJ38441.1 - 0.88 10.6 4.9 7.6 7.6 2.4 2.4 2 0 0 2 2 2 0 E4 protein DUF2894 PF11445.8 CDJ38441.1 - 1.4 9.3 17.0 0.23 11.9 5.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) MAJIN PF15077.6 CDJ38441.1 - 4 7.2 6.2 1.2 8.9 1.2 2.1 2 0 0 2 2 2 0 Membrane-anchored junction protein Dehydrin PF00257.19 CDJ38441.1 - 5.4 7.6 26.8 0.89 10.1 0.6 2.9 2 1 0 2 2 2 0 Dehydrin DUF4551 PF15087.6 CDJ38442.1 - 0.49 9.2 10.0 0.5 9.1 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 CDJ38442.1 - 0.91 8.2 13.5 0.97 8.1 13.5 1.0 1 0 0 1 1 1 0 Presenilin Baculo_PP31 PF05311.11 CDJ38442.1 - 1.9 7.9 7.1 2.1 7.8 7.1 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SLC12 PF03522.15 CDJ38442.1 - 2.7 6.9 10.3 3 6.8 10.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Cellulose_synt PF03552.14 CDJ38442.1 - 3.1 6.2 3.5 3 6.2 3.5 1.1 1 0 0 1 1 1 0 Cellulose synthase Spt20 PF12090.8 CDJ38442.1 - 3.1 7.3 43.3 0.78 9.3 11.2 2.0 2 0 0 2 2 2 0 Spt20 family V_ATPase_I PF01496.19 CDJ38442.1 - 9.5 4.0 12.9 11 3.8 12.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FF PF01846.19 CDJ38443.1 - 3.3e-12 46.4 0.0 1.6e-05 25.0 0.1 2.6 2 0 0 2 2 2 2 FF domain SpmSyn_N PF17950.1 CDJ38443.1 - 0.079 13.2 0.4 1 9.6 0.0 2.6 2 0 0 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal Exonuc_VII_L PF02601.15 CDJ38444.1 - 0.86 9.1 22.6 1 8.9 22.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Asp-B-Hydro_N PF05279.11 CDJ38444.1 - 1 9.4 11.8 1.1 9.2 11.8 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pex14_N PF04695.13 CDJ38444.1 - 1.1 9.9 21.6 1.7 9.3 21.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CemA PF03040.14 CDJ38444.1 - 1.9 8.4 10.7 2.2 8.2 10.7 1.2 1 0 0 1 1 1 0 CemA family CTI PF06934.11 CDJ38444.1 - 3.6 6.0 14.4 3.9 5.9 14.4 1.0 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) Miga PF10265.9 CDJ38444.1 - 5.8 5.8 11.5 6.3 5.7 11.5 1.0 1 0 0 1 1 1 0 Mitoguardin Spt20 PF12090.8 CDJ38445.1 - 0.0011 18.6 21.7 0.0011 18.6 21.7 2.5 2 1 0 2 2 2 1 Spt20 family RskA PF10099.9 CDJ38445.1 - 0.0033 17.7 9.2 0.0033 17.7 9.2 2.3 2 0 0 2 2 2 1 Anti-sigma-K factor rskA FGAR-AT_N PF18076.1 CDJ38445.1 - 1 9.4 6.0 3.3 7.7 0.8 2.7 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase N-terminal Ribosomal_60s PF00428.19 CDJ38445.1 - 1.5 9.5 11.8 5.8 7.6 11.8 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3597 PF12200.8 CDJ38446.1 - 0.01 16.4 7.5 1.6 9.2 5.5 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3597) SUIM_assoc PF16619.5 CDJ38446.1 - 0.021 14.9 19.4 2.1 8.5 6.0 3.6 2 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TIM PF00121.18 CDJ38446.1 - 0.027 13.9 0.1 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 Triosephosphate isomerase CBP_BcsG PF11658.8 CDJ38446.1 - 0.26 9.6 2.3 0.41 9.0 2.3 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG CCDC53 PF10152.9 CDJ38446.1 - 0.33 11.3 2.2 0.88 10.0 2.2 1.7 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2057 PF09829.9 CDJ38446.1 - 4.4 7.4 14.3 1.3 9.2 10.3 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) ChAPs PF09295.10 CDJ38448.1 - 0.00068 18.7 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) HTH_18 PF12833.7 CDJ38450.1 - 0.15 12.3 0.9 0.24 11.7 0.9 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain PepSY_2 PF13670.6 CDJ38456.1 - 2.5 8.1 7.7 4 7.5 0.7 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain TMEM100 PF16311.5 CDJ38457.1 - 0.23 11.1 2.1 0.64 9.6 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 100 NUDE_C PF04880.13 CDJ38458.1 - 0.0097 16.4 7.3 0.012 16.2 7.3 1.2 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region DUF755 PF05501.11 CDJ38458.1 - 0.034 14.4 15.8 0.066 13.5 15.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) PI3K_1B_p101 PF10486.9 CDJ38458.1 - 0.09 10.5 3.5 0.088 10.6 3.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4718 PF15842.5 CDJ38458.1 - 0.098 12.4 5.2 0.14 12.0 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) DUF1635 PF07795.11 CDJ38458.1 - 0.099 12.5 7.2 0.14 12.0 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Roughex PF06020.11 CDJ38458.1 - 0.12 11.5 9.8 0.14 11.3 9.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Macoilin PF09726.9 CDJ38458.1 - 0.44 9.0 8.4 0.47 9.0 8.4 1.0 1 0 0 1 1 1 0 Macoilin family MPM1 PF17234.2 CDJ38458.1 - 0.77 10.0 7.8 1.1 9.5 7.8 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 CCDC106 PF15794.5 CDJ38458.1 - 0.79 9.4 9.1 0.99 9.1 9.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 PAP1 PF08601.10 CDJ38458.1 - 0.95 9.1 18.1 1.1 8.9 18.1 1.3 1 1 0 1 1 1 0 Transcription factor PAP1 CDK2AP PF09806.9 CDJ38458.1 - 1.2 9.2 17.7 1.8 8.6 17.7 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein GREB1 PF15782.5 CDJ38458.1 - 1.3 6.1 10.4 1.4 5.9 10.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 CDJ38458.1 - 1.3 9.0 17.6 1.4 8.8 17.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM199X PF15814.5 CDJ38458.1 - 1.3 8.0 10.4 1.6 7.7 10.4 1.2 1 0 0 1 1 1 0 Protein family FAM199X SLC12 PF03522.15 CDJ38458.1 - 1.5 7.8 5.2 1.4 7.8 5.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 CDJ38458.1 - 1.7 8.1 9.3 1.9 8.0 9.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 CDJ38458.1 - 2.4 6.9 10.8 2.1 7.0 10.8 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CDJ38458.1 - 2.5 6.3 8.2 2.3 6.4 8.2 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ38458.1 - 4.1 7.2 8.0 4.6 7.0 8.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.9 CDJ38458.1 - 5.4 5.8 10.6 5.4 5.8 10.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 CDJ38458.1 - 5.7 5.1 8.1 6.8 4.8 8.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Miga PF10265.9 CDJ38458.1 - 6.4 5.6 8.2 6.9 5.5 8.2 1.0 1 0 0 1 1 1 0 Mitoguardin Peptidase_S64 PF08192.11 CDJ38458.1 - 6.6 5.1 9.3 6.2 5.2 9.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.10 CDJ38458.1 - 6.6 5.3 12.2 7.2 5.2 12.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Paf1 PF03985.13 CDJ38458.1 - 7.7 5.4 20.0 9.4 5.1 20.0 1.1 1 0 0 1 1 1 0 Paf1 DUF4407 PF14362.6 CDJ38458.1 - 9.9 5.4 9.4 10 5.4 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SIMPL PF04402.14 CDJ38461.1 - 0.12 12.8 0.2 0.12 12.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF541) NIF PF03031.18 CDJ38462.1 - 5.1e-26 91.3 0.0 4.1e-25 88.4 0.0 2.4 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase SNase PF00565.17 CDJ38464.1 - 3.3e-08 34.0 0.0 4.4e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Ribosomal_60s PF00428.19 CDJ38464.1 - 0.14 12.8 2.4 0.34 11.5 2.5 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein 17kDa_Anti_2 PF16998.5 CDJ38466.1 - 0.024 14.6 0.6 0.027 14.4 0.6 1.2 1 0 0 1 1 1 0 17 kDa outer membrane surface antigen TFIIA PF03153.13 CDJ38467.1 - 0.012 15.6 20.3 0.021 14.8 20.3 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EOS1 PF12326.8 CDJ38467.1 - 0.14 12.1 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 N-glycosylation protein Neur_chan_memb PF02932.16 CDJ38467.1 - 0.29 11.1 2.3 0.39 10.7 2.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ38467.1 - 0.84 8.3 9.8 1.1 8.0 9.8 1.1 1 0 0 1 1 1 0 Presenilin Glt_symporter PF03616.14 CDJ38467.1 - 1.7 7.3 2.2 2.3 6.8 2.2 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF5345 PF17280.2 CDJ38469.1 - 5.6 7.0 13.5 0.18 11.8 7.1 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5345) CWC25 PF12542.8 CDJ38471.1 - 0.029 15.3 1.2 0.029 15.3 1.2 2.1 2 1 1 3 3 3 0 Pre-mRNA splicing factor Apt1 PF10351.9 CDJ38471.1 - 0.15 10.9 11.6 0.17 10.7 11.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ38471.1 - 0.48 10.3 13.8 0.56 10.1 13.8 1.1 1 0 0 1 1 1 0 SPX domain ACC_epsilon PF13822.6 CDJ38471.1 - 1.2 9.8 12.9 0.4 11.4 8.9 2.0 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Secretin_N_2 PF07655.13 CDJ38471.1 - 9.4 6.9 24.0 0.98 10.0 5.6 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Pkinase PF00069.25 CDJ38472.1 - 7.1e-12 45.2 0.1 4.1e-09 36.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ38472.1 - 3.3e-07 29.9 0.2 1.7e-06 27.5 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RskA PF10099.9 CDJ38472.1 - 0.0008 19.7 12.0 0.00099 19.4 12.0 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ38472.1 - 0.0059 16.7 1.6 0.0059 16.7 1.6 2.4 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ38472.1 - 0.16 11.5 3.4 0.26 10.9 3.4 1.3 1 0 0 1 1 1 0 Spt20 family INCENP_ARK-bind PF03941.15 CDJ38474.1 - 4.8e-05 23.2 0.0 0.0002 21.3 0.0 2.1 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region S1-P1_nuclease PF02265.16 CDJ38476.1 - 2e-33 116.3 2.0 1.8e-25 90.2 0.6 2.3 2 0 0 2 2 2 2 S1/P1 Nuclease DUF2722 PF10846.8 CDJ38476.1 - 0.0059 15.6 5.4 0.0059 15.6 5.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ38476.1 - 0.017 15.1 33.0 0.033 14.2 16.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2076 PF09849.9 CDJ38476.1 - 0.66 10.0 36.6 0.068 13.2 13.9 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Lin-8 PF03353.15 CDJ38476.1 - 1.2 8.6 8.6 0.22 11.0 1.5 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Neur_chan_memb PF02932.16 CDJ38476.1 - 5.3 7.0 8.6 2.2 8.3 2.7 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Rxt3 PF08642.10 CDJ38476.1 - 6.3 7.6 5.3 10 6.9 1.0 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 RskA PF10099.9 CDJ38477.1 - 0.0011 19.3 0.1 0.0011 19.3 0.1 8.3 3 2 2 6 6 6 2 Anti-sigma-K factor rskA FATC PF02260.20 CDJ38478.1 - 7.8e-14 51.2 0.3 9.8e-13 47.7 0.1 2.6 2 0 0 2 2 2 1 FATC domain PI3_PI4_kinase PF00454.27 CDJ38478.1 - 1.4e-07 31.6 0.1 5.6e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase zf-ANAPC11 PF12861.7 CDJ38479.1 - 4.1e-21 74.8 6.1 5.4e-21 74.4 6.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CDJ38479.1 - 4.2e-19 68.6 8.8 7e-19 67.9 8.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CDJ38479.1 - 7.7e-08 32.5 7.9 5.5e-07 29.8 7.9 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CDJ38479.1 - 1.1e-06 28.5 4.7 2.2e-06 27.5 4.7 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ38479.1 - 0.00011 22.0 2.2 0.00024 20.9 2.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ38479.1 - 0.0019 18.2 7.3 0.007 16.4 6.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ38479.1 - 0.019 14.8 7.4 0.4 10.6 6.8 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ38479.1 - 0.039 13.8 6.4 0.15 11.9 6.2 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CDJ38479.1 - 0.3 10.7 9.8 1 9.0 9.5 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RanBP PF00641.18 CDJ38479.1 - 0.66 9.3 0.0 0.66 9.3 0.0 2.6 2 1 1 3 3 3 0 Zn-finger in Ran binding protein and others zf-RING_11 PF17123.5 CDJ38479.1 - 1.6 8.5 15.9 11 5.8 15.9 2.3 1 1 0 1 1 1 0 RING-like zinc finger Pkinase PF00069.25 CDJ38480.1 - 1.5e-06 27.8 0.0 0.0008 18.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Myb_DNA-bind_6 PF13921.6 CDJ38481.1 - 1.4e-05 25.2 1.1 2.4e-05 24.5 1.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CDJ38481.1 - 0.0014 18.8 0.3 0.0022 18.1 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 CDJ38481.1 - 0.0037 17.4 0.7 0.0057 16.8 0.7 1.2 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 CDJ38481.1 - 0.21 11.6 0.1 0.34 10.9 0.1 1.3 1 0 0 1 1 1 0 SLIDE Tmp39 PF10271.9 CDJ38482.1 - 0.22 10.5 8.1 0.46 9.4 8.1 1.4 1 0 0 1 1 1 0 Putative transmembrane protein Sua5_yciO_yrdC PF01300.18 CDJ38483.1 - 0.062 12.8 0.0 10 5.6 0.0 2.6 2 0 0 2 2 2 0 Telomere recombination TFIIF_beta_N PF17683.1 CDJ38483.1 - 0.091 13.4 2.5 0.19 12.4 2.5 1.6 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus Pox_G7 PF05503.12 CDJ38483.1 - 0.096 11.6 3.7 0.036 13.0 0.3 1.8 2 0 0 2 2 2 0 Poxvirus G7-like TFIIA PF03153.13 CDJ38483.1 - 0.32 10.9 18.3 0.63 10.0 18.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 CDJ38483.1 - 0.61 8.2 18.0 0.89 7.6 18.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SUIM_assoc PF16619.5 CDJ38483.1 - 1.3 9.1 27.9 0.7 10.0 13.4 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 cNMP_binding PF00027.29 CDJ38484.1 - 5.3e-59 196.3 3.0 5.5e-19 68.0 0.0 5.1 5 1 0 5 5 5 4 Cyclic nucleotide-binding domain Pkinase PF00069.25 CDJ38484.1 - 5.4e-09 35.8 0.2 5.4e-09 35.8 0.2 4.7 4 2 1 5 5 5 2 Protein kinase domain Cupin_2 PF07883.11 CDJ38484.1 - 2e-05 24.2 1.5 1.2 8.9 0.0 4.9 5 0 0 5 5 5 2 Cupin domain Draxin PF15550.6 CDJ38484.1 - 0.35 10.7 18.9 0.68 9.8 18.9 1.4 1 0 0 1 1 1 0 Draxin CRT10 PF08728.10 CDJ38484.1 - 0.61 8.2 6.4 1.7 6.7 6.5 1.7 2 0 0 2 2 2 0 CRT10 TFIIA PF03153.13 CDJ38484.1 - 1.2 9.1 38.4 2.4 8.1 38.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 CDJ38484.1 - 1.8 7.2 13.3 2.6 6.6 13.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DDHD PF02862.17 CDJ38484.1 - 2.1 8.4 10.6 3.5 7.7 9.0 2.1 2 0 0 2 2 2 0 DDHD domain DHC_N1 PF08385.12 CDJ38486.1 - 3.2e-120 402.4 2.0 3.2e-120 402.4 2.0 3.2 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CDJ38486.1 - 1.4e-112 376.8 9.0 1.4e-112 376.8 9.0 2.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 PSD1 PF07587.11 CDJ38486.1 - 0.00078 19.0 0.1 0.31 10.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1553) INCENP_N PF12178.8 CDJ38486.1 - 0.055 13.5 0.2 2.5 8.2 0.0 3.3 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal ORC_WH_C PF18137.1 CDJ38486.1 - 1.6 8.8 4.5 1.4 8.9 0.3 2.8 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal AAA_6 PF12774.7 CDJ38487.1 - 4.1e-18 65.4 0.0 4.2e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 CDJ38488.1 - 8.7e-84 280.9 0.0 2e-81 273.2 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDJ38488.1 - 6.3e-77 257.6 1.8 2.2e-76 255.8 1.8 2.0 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDJ38488.1 - 7.7e-66 221.1 0.2 2.2e-65 219.6 0.1 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region MT PF12777.7 CDJ38488.1 - 4.9e-60 203.4 16.6 6.2e-60 203.0 15.7 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 CDJ38488.1 - 2.3e-48 164.8 0.1 8e-47 159.8 0.0 3.2 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region Dynein_AAA_lid PF17852.1 CDJ38488.1 - 3.4e-24 85.4 2.1 1.2e-23 83.6 2.1 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ38488.1 - 4.7e-23 81.3 0.1 1.1e-22 80.1 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ38488.1 - 6.5e-16 58.6 0.0 2.7e-05 24.2 0.0 4.5 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CDJ38488.1 - 6.3e-05 23.5 1.7 0.0011 19.5 0.0 3.2 4 0 0 4 4 2 1 ABC transporter AAA_29 PF13555.6 CDJ38488.1 - 0.00033 20.3 0.1 0.04 13.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_14 PF13173.6 CDJ38488.1 - 0.0012 18.9 0.6 0.0084 16.1 0.0 2.6 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 CDJ38488.1 - 0.0028 16.8 0.0 0.14 11.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 CDJ38488.1 - 0.0057 17.1 9.9 0.0068 16.8 0.0 4.7 5 1 1 6 6 6 1 AAA ATPase domain AAA_22 PF13401.6 CDJ38488.1 - 0.0077 16.5 0.0 0.077 13.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain TniB PF05621.11 CDJ38488.1 - 0.011 15.2 0.0 0.17 11.3 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein Mg_chelatase PF01078.21 CDJ38488.1 - 0.017 14.5 0.0 1.6 8.1 0.0 2.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 CDJ38488.1 - 0.023 14.4 0.1 2.8 7.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CDJ38488.1 - 0.028 14.6 0.3 1.8 8.8 0.0 3.7 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 CDJ38488.1 - 0.04 14.2 0.0 3.7 7.9 0.0 3.2 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 CDJ38488.1 - 0.048 12.8 0.0 0.048 12.8 0.0 2.8 4 0 0 4 4 3 0 G-protein alpha subunit DUF573 PF04504.14 CDJ38488.1 - 0.068 13.8 0.3 0.63 10.7 0.2 2.7 2 0 0 2 2 1 0 Protein of unknown function, DUF573 AAA PF00004.29 CDJ38488.1 - 0.085 13.3 0.0 2.5 8.5 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CDJ38488.1 - 0.11 12.4 0.1 1.6 8.7 0.0 2.9 3 0 0 3 3 2 0 RsgA GTPase ATP-synt_ab PF00006.25 CDJ38488.1 - 0.12 12.0 0.0 6.1 6.4 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 CDJ38488.1 - 0.13 12.2 0.0 0.56 10.2 0.0 2.1 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ISG65-75 PF11727.8 CDJ38488.1 - 5.5 6.1 21.7 0.77 8.9 11.0 2.3 2 0 0 2 2 2 0 Invariant surface glycoprotein Dynein_heavy PF03028.15 CDJ38489.1 - 1.1e-06 28.8 0.0 2.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 CDJ38490.1 - 1.2e-54 185.7 0.0 2.4e-44 151.8 0.0 2.1 1 1 1 2 2 2 2 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CDJ38490.1 - 3.8e-41 140.6 0.0 5.7e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ38490.1 - 1.9e-24 86.0 0.0 2e-23 82.7 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain PRY PF13765.6 CDJ38491.1 - 0.33 10.6 1.6 0.39 10.4 0.3 1.8 2 0 0 2 2 2 0 SPRY-associated domain Big_3_5 PF16640.5 CDJ38491.1 - 4.1 7.6 9.0 1.5 9.0 0.9 2.9 3 1 0 3 3 3 0 Bacterial Ig-like domain (group 3) G0-G1_switch_2 PF15103.6 CDJ38492.1 - 0.057 13.9 0.4 0.17 12.3 0.4 1.8 1 0 0 1 1 1 0 G0/G1 switch protein 2 LRR_4 PF12799.7 CDJ38495.1 - 9.5e-16 57.7 29.0 7.6e-07 29.4 0.4 3.8 1 1 5 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ38495.1 - 7.5e-11 41.6 14.2 0.00011 21.9 0.3 3.6 2 2 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 CDJ38495.1 - 2.6e-05 23.8 0.7 0.0027 17.2 0.4 2.1 2 0 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CDJ38495.1 - 3.6e-05 23.5 13.6 0.07 13.2 0.3 5.7 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 CDJ38495.1 - 0.062 13.9 10.6 1.2 10.0 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich Repeat DUF1524 PF07510.11 CDJ38496.1 - 0.096 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) InaF-motif PF15018.6 CDJ38496.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 TRP-interacting helix LRR_8 PF13855.6 CDJ38497.1 - 1.7e-05 24.5 4.7 0.00016 21.4 0.1 3.1 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 CDJ38497.1 - 0.0016 18.8 4.9 0.018 15.4 1.1 3.4 2 2 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ38497.1 - 0.0049 16.4 0.1 0.015 14.8 0.0 1.8 2 0 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 CDJ38497.1 - 0.41 11.4 1.7 18 6.4 0.7 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_9 PF14580.6 CDJ38498.1 - 8.5e-32 110.0 2.8 7.9e-13 48.3 0.1 4.4 2 2 3 5 5 5 4 Leucine-rich repeat LRR_8 PF13855.6 CDJ38498.1 - 3.4e-27 94.0 15.2 4.6e-07 29.5 0.9 6.0 4 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 CDJ38498.1 - 9.2e-27 92.7 21.7 8.1e-07 29.3 0.1 7.5 6 2 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ38498.1 - 2.2e-05 24.1 21.6 0.062 13.4 0.3 8.8 9 1 1 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 CDJ38498.1 - 0.00034 20.8 29.9 0.59 10.9 0.0 9.1 9 1 0 9 9 9 3 Leucine Rich Repeat Pou PF00157.17 CDJ38498.1 - 0.083 12.9 0.2 4 7.5 0.0 2.9 3 0 0 3 3 3 0 Pou domain - N-terminal to homeobox domain DUF5600 PF18150.1 CDJ38499.1 - 0.17 12.5 0.3 1 10.0 0.1 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF5600) COPI_assoc PF08507.10 CDJ38500.1 - 3.5e-10 40.0 4.9 4.5e-10 39.7 4.9 1.1 1 0 0 1 1 1 1 COPI associated protein Hydrolase_4 PF12146.8 CDJ38501.1 - 7.4e-22 77.8 0.3 6.4e-11 42.0 0.0 3.2 3 1 0 3 3 3 2 Serine aminopeptidase, S33 PGAP1 PF07819.13 CDJ38501.1 - 0.095 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Amino_oxidase PF01593.24 CDJ38502.1 - 3.7e-15 56.2 18.1 9.5e-05 21.9 3.2 3.6 4 0 0 4 4 4 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ38502.1 - 2.9e-09 37.0 0.9 1.8e-08 34.4 0.9 2.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ38502.1 - 7.6e-06 25.4 1.3 1.8e-05 24.1 1.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDJ38502.1 - 8e-06 25.3 0.4 1.5e-05 24.4 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CDJ38502.1 - 0.00014 22.3 1.1 0.00029 21.3 1.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ38502.1 - 0.00033 19.5 1.4 0.00057 18.7 1.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 CDJ38502.1 - 0.0014 17.9 0.1 0.0028 16.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDJ38502.1 - 0.0074 15.4 1.7 0.016 14.3 1.7 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CDJ38502.1 - 0.032 13.3 7.2 0.08 12.0 2.6 3.2 1 1 1 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 CDJ38502.1 - 0.093 12.0 2.3 0.16 11.1 2.3 1.3 1 0 0 1 1 1 0 Thi4 family RRM_1 PF00076.22 CDJ38503.1 - 2.1e-39 133.2 0.0 1.3e-20 72.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ38503.1 - 9.7e-08 31.7 0.0 0.0071 15.9 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ38503.1 - 0.00037 20.5 0.1 0.15 12.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 CDJ38503.1 - 0.0073 16.0 0.1 4.3 7.1 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease B OB domain PsbQ PF05757.11 CDJ38504.1 - 0.2 11.4 6.2 0.08 12.7 0.7 2.9 2 1 1 3 3 3 0 Oxygen evolving enhancer protein 3 (PsbQ) PIG-L PF02585.17 CDJ38504.1 - 0.41 11.3 2.9 0.8 10.3 0.0 2.7 3 0 0 3 3 3 0 GlcNAc-PI de-N-acetylase SCIMP PF15050.6 CDJ38504.1 - 2.8 8.4 5.5 0.66 10.4 0.9 2.1 2 0 0 2 2 2 0 SCIMP protein MMR_HSR1_C PF08438.10 CDJ38505.1 - 9e-24 84.2 0.0 1.7e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 CDJ38505.1 - 2.7e-19 69.4 0.0 6.3e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ38505.1 - 3e-06 26.8 0.1 9.6e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 CDJ38505.1 - 0.0035 17.4 0.0 0.0076 16.3 0.0 1.6 1 0 0 1 1 1 1 TGS domain ATP_bind_1 PF03029.17 CDJ38505.1 - 0.1 12.4 1.7 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PCP_red PF08369.10 CDJ38507.1 - 0.7 10.2 4.0 0.75 10.1 0.2 2.5 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit LRR_6 PF13516.6 CDJ38508.1 - 2.7e-05 23.9 2.4 0.95 9.7 0.2 3.7 3 0 0 3 3 3 2 Leucine Rich repeat CemA PF03040.14 CDJ38508.1 - 0.38 10.6 1.5 1 9.2 1.5 1.7 1 0 0 1 1 1 0 CemA family CRAL_TRIO PF00650.20 CDJ38509.1 - 2.4e-22 79.3 0.0 5.1e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ38509.1 - 3.3e-07 30.5 0.0 7.1e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CDJ38509.1 - 0.0074 16.5 2.8 0.0074 16.5 2.8 2.7 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain BAALC_N PF06989.12 CDJ38509.1 - 0.061 13.7 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 BAALC N-terminus 7tm_6 PF02949.20 CDJ38511.1 - 2.8 6.9 4.7 8.2 5.4 0.2 2.4 2 0 0 2 2 2 0 7tm Odorant receptor ThiF PF00899.21 CDJ38512.1 - 1.4e-47 162.1 0.0 1.3e-44 152.4 0.0 2.3 1 1 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 CDJ38512.1 - 1.3e-09 38.5 0.0 4e-09 36.9 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain SR-25 PF10500.9 CDJ38512.1 - 6e-05 22.8 18.2 6e-05 22.8 18.2 3.9 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein Shikimate_DH PF01488.20 CDJ38512.1 - 0.07 13.2 0.5 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1480 PF07351.13 CDJ38512.1 - 0.079 13.2 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) Polysacc_synt_2 PF02719.15 CDJ38512.1 - 0.11 11.6 0.0 0.24 10.5 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Enolase_C PF00113.22 CDJ38513.1 - 5.8e-143 475.5 0.0 7.4e-143 475.2 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CDJ38513.1 - 1.1e-50 171.2 0.0 1.1e-50 171.2 0.0 2.0 1 1 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CDJ38513.1 - 1.9e-13 50.5 0.1 1.9e-13 50.5 0.1 2.4 2 1 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CDJ38513.1 - 4.3e-06 26.1 0.0 7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Retinal PF15449.6 CDJ38513.1 - 2.8 5.6 11.4 3.7 5.2 11.4 1.0 1 0 0 1 1 1 0 Retinal protein tRNA_synthFbeta PF17759.1 CDJ38514.1 - 3.3e-31 108.4 0.0 6.3e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CDJ38514.1 - 2e-26 92.0 0.0 4.2e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 CDJ38514.1 - 1.3e-12 47.8 0.0 8e-10 38.9 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain B3_4 PF03483.17 CDJ38514.1 - 8.7e-10 38.5 0.0 1.2e-05 25.1 0.0 2.7 2 0 0 2 2 2 2 B3/4 domain tRNA-synt_2d PF01409.20 CDJ38514.1 - 0.023 14.2 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) DUF4805 PF16063.5 CDJ38514.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Apolipoprotein PF01442.18 CDJ38516.1 - 3 7.7 47.7 5.3 6.9 31.1 3.6 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain Prominin PF05478.11 CDJ38516.1 - 3.5 5.4 4.8 2.8 5.8 2.5 1.8 2 0 0 2 2 2 0 Prominin DUF1664 PF07889.12 CDJ38516.1 - 4.1 7.5 8.8 19 5.3 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CDJ38516.1 - 4.5 7.4 9.4 1.7 8.9 4.8 2.4 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Laminin_N PF00055.17 CDJ38518.1 - 0.16 11.5 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Laminin N-terminal (Domain VI) AAA_29 PF13555.6 CDJ38519.1 - 0.0023 17.6 0.1 0.0044 16.7 0.0 1.5 1 1 1 2 2 2 1 P-loop containing region of AAA domain G-alpha PF00503.20 CDJ38519.1 - 0.0043 16.3 0.0 0.0048 16.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Roc PF08477.13 CDJ38519.1 - 0.005 17.1 0.0 0.0061 16.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CDJ38519.1 - 0.011 16.2 0.0 0.011 16.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 CDJ38519.1 - 0.033 13.7 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 CDJ38519.1 - 0.035 13.9 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 CDJ38519.1 - 0.049 13.9 0.0 0.056 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CDJ38519.1 - 0.064 13.8 0.0 0.086 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3449 PF11931.8 CDJ38520.1 - 0.033 14.0 0.2 0.033 14.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) YcaO PF02624.16 CDJ38522.1 - 0.0032 16.8 0.1 0.0045 16.3 0.1 1.2 1 0 0 1 1 1 1 YcaO cyclodehydratase, ATP-ad Mg2+-binding PPE PF00823.19 CDJ38522.1 - 0.014 15.5 0.3 0.03 14.4 0.3 1.5 1 0 0 1 1 1 0 PPE family Spt20 PF12090.8 CDJ38522.1 - 1.2 8.7 6.1 2 8.0 6.1 1.3 1 0 0 1 1 1 0 Spt20 family CWC25 PF12542.8 CDJ38523.1 - 1.6e-07 32.2 0.2 1.6e-07 32.2 0.2 3.6 2 1 0 2 2 2 1 Pre-mRNA splicing factor VIR_N PF15912.5 CDJ38523.1 - 3.1 7.3 5.5 5.5 6.5 5.5 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal CDC45 PF02724.14 CDJ38523.1 - 4 5.6 15.6 4.9 5.3 15.6 1.4 1 0 0 1 1 1 0 CDC45-like protein SOG2 PF10428.9 CDJ38523.1 - 8.3 5.5 30.5 11 5.1 30.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Nucleo_P87 PF07267.11 CDJ38523.1 - 8.4 5.1 10.7 11 4.8 10.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FTR PF01913.18 CDJ38525.1 - 0.35 10.8 7.3 0.24 11.3 2.2 2.4 2 0 0 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase YdjM PF04307.14 CDJ38525.1 - 1.5 8.1 6.8 3 7.1 6.8 1.5 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Spt5-NGN PF03439.13 CDJ38526.1 - 6.7e-07 29.1 0.0 7.1e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CCDC106 PF15794.5 CDJ38527.1 - 0.051 13.3 6.2 0.054 13.2 6.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4710 PF15828.5 CDJ38527.1 - 0.066 13.3 6.4 0.094 12.8 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) U3_snoRNA_assoc PF08297.11 CDJ38527.1 - 0.22 12.2 8.6 0.33 11.7 8.6 1.2 1 0 0 1 1 1 0 U3 snoRNA associated UPF0688 PF15772.5 CDJ38527.1 - 0.38 11.0 10.6 0.46 10.7 10.6 1.0 1 0 0 1 1 1 0 UPF0688 family CDC45 PF02724.14 CDJ38527.1 - 0.81 7.9 4.5 0.85 7.8 4.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Rrn6 PF10214.9 CDJ38527.1 - 1.6 7.1 7.9 1.8 7.0 7.9 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PI3K_1B_p101 PF10486.9 CDJ38527.1 - 1.7 6.3 4.1 1.9 6.2 4.1 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Coilin_N PF15862.5 CDJ38527.1 - 7.4 6.4 9.2 9.8 6.0 9.2 1.2 1 0 0 1 1 1 0 Coilin N-terminus Presenilin PF01080.17 CDJ38527.1 - 8.8 5.0 5.0 10 4.8 5.0 1.0 1 0 0 1 1 1 0 Presenilin CENP-H PF05837.12 CDJ38529.1 - 0.03 14.7 3.0 0.03 14.7 3.0 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Sperm_Ag_HE2 PF05324.13 CDJ38529.1 - 0.18 12.3 6.4 0.26 11.8 1.6 2.7 2 0 0 2 2 2 0 Sperm antigen HE2 DUF4446 PF14584.6 CDJ38529.1 - 0.23 11.4 3.4 5.2 7.0 3.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) TFIIA PF03153.13 CDJ38529.1 - 0.49 10.3 21.1 0.25 11.3 1.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MTABC_N PF16185.5 CDJ38529.1 - 1.7 8.1 4.3 0.32 10.5 0.3 1.8 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region DivIC PF04977.15 CDJ38529.1 - 3.3 7.5 22.2 0.4 10.5 5.2 3.4 3 0 0 3 3 3 0 Septum formation initiator DUF2721 PF11026.8 CDJ38529.1 - 8.6 6.3 8.4 5.6 6.9 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Motile_Sperm PF00635.26 CDJ38530.1 - 5.5e-21 74.5 0.0 1e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain BRE1 PF08647.11 CDJ38530.1 - 0.014 15.5 1.0 0.025 14.6 1.0 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 CDJ38530.1 - 0.025 14.7 2.4 0.025 14.7 2.4 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FixG_C PF11614.8 CDJ38530.1 - 0.025 14.8 0.1 0.18 12.0 0.0 2.2 1 1 1 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF5001 PF16392.5 CDJ38530.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Ig-like domain TEBP_beta PF07404.11 CDJ38530.1 - 0.17 11.2 2.3 0.21 10.9 2.3 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) CCDC106 PF15794.5 CDJ38530.1 - 6.3 6.4 7.5 0.71 9.5 2.1 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 PEN-2 PF10251.9 CDJ38531.1 - 0.0021 18.4 1.6 0.042 14.3 0.0 2.2 1 1 1 2 2 2 2 Presenilin enhancer-2 subunit of gamma secretase DUF2722 PF10846.8 CDJ38533.1 - 0.00016 20.7 24.0 0.00022 20.3 6.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) BRF1 PF07741.13 CDJ38533.1 - 0.0041 17.4 10.7 0.092 13.1 2.9 2.2 2 0 0 2 2 2 2 Brf1-like TBP-binding domain TFIIA PF03153.13 CDJ38533.1 - 0.007 16.4 10.3 0.007 16.4 10.3 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.6 CDJ38533.1 - 0.021 15.3 0.2 0.021 15.3 0.2 2.1 2 0 0 2 2 2 0 AAA domain DDHD PF02862.17 CDJ38533.1 - 0.024 14.8 1.5 0.99 9.5 0.1 2.1 2 0 0 2 2 2 0 DDHD domain Exonuc_VII_L PF02601.15 CDJ38533.1 - 0.025 14.1 9.4 0.046 13.3 0.8 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit DivIC PF04977.15 CDJ38533.1 - 0.034 13.9 31.6 0.095 12.5 10.1 2.4 2 0 0 2 2 2 0 Septum formation initiator EPL1 PF10513.9 CDJ38533.1 - 0.052 13.9 7.9 0.15 12.5 0.2 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like EMC3_TMCO1 PF01956.16 CDJ38533.1 - 0.098 12.4 7.8 2.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF2828 PF11443.8 CDJ38533.1 - 0.16 10.0 1.7 0.29 9.2 1.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2828) DUF1645 PF07816.11 CDJ38533.1 - 0.22 12.1 3.5 2.5 8.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) RRP36 PF06102.12 CDJ38533.1 - 0.26 11.3 17.5 0.93 9.4 3.1 2.1 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 Tim54 PF11711.8 CDJ38533.1 - 0.27 10.0 4.7 0.43 9.3 0.2 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Spt20 PF12090.8 CDJ38533.1 - 0.29 10.7 44.1 0.64 9.6 21.7 2.1 2 0 0 2 2 2 0 Spt20 family SpoIIP PF07454.11 CDJ38533.1 - 0.31 10.5 7.6 0.42 10.0 0.6 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) TERB2 PF15101.6 CDJ38533.1 - 0.56 10.2 17.6 0.17 11.9 3.9 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF702 PF05142.12 CDJ38533.1 - 0.7 10.4 13.1 1.5 9.3 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF4770 PF15994.5 CDJ38533.1 - 2.6 8.3 15.8 1.6 9.0 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Eapp_C PF10238.9 CDJ38533.1 - 3.2 7.8 11.3 0.98 9.5 1.3 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein Band_3_cyto PF07565.13 CDJ38533.1 - 4.3 7.1 9.2 1.2 8.8 0.7 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF4355 PF14265.6 CDJ38533.1 - 4.8 7.4 20.6 0.34 11.2 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF45 PF01863.17 CDJ38533.1 - 6.9 6.7 9.8 8.3 6.4 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 CNDH2_M PF16869.5 CDJ38533.1 - 7 7.3 14.6 4.7 7.9 2.0 2.3 2 1 0 2 2 2 0 PF16858 ANAPC_CDC26 PF10471.9 CDJ38533.1 - 9.2 7.2 39.6 0.54 11.1 9.4 3.0 3 0 0 3 3 2 0 Anaphase-promoting complex APC subunit CDC26 DUF2722 PF10846.8 CDJ38534.1 - 0.00027 20.0 4.5 0.00027 20.0 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ38534.1 - 0.021 13.8 16.4 0.03 13.3 16.4 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 MAP65_ASE1 PF03999.12 CDJ38534.1 - 0.051 12.3 4.4 0.054 12.2 4.4 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Spt20 PF12090.8 CDJ38534.1 - 0.08 12.5 15.1 0.092 12.3 15.1 1.1 1 0 0 1 1 1 0 Spt20 family SARAF PF06682.12 CDJ38534.1 - 0.084 12.5 3.1 0.084 12.5 3.1 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Neur_chan_memb PF02932.16 CDJ38534.1 - 0.41 10.7 2.1 0.4 10.7 2.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 CDJ38534.1 - 0.42 11.6 4.9 0.56 11.2 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ38534.1 - 0.67 8.7 4.1 0.63 8.7 4.1 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ38534.1 - 1.8 7.2 14.1 2 7.0 14.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Herpes_DNAp_acc PF04929.12 CDJ38534.1 - 1.8 7.5 10.2 1.7 7.5 10.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor IER PF05760.12 CDJ38534.1 - 3.4 7.9 20.4 3.9 7.7 20.4 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) TMEM171 PF15471.6 CDJ38534.1 - 4.5 6.2 8.7 4.6 6.1 8.2 1.3 1 1 0 1 1 1 0 Transmembrane protein family 171 NUDE_C PF04880.13 CDJ38534.1 - 4.9 7.6 12.5 7.2 7.1 12.5 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Myosin_head PF00063.21 CDJ38535.1 - 1e-13 50.5 1.7 1.2e-09 36.9 0.1 3.8 2 2 2 4 4 4 3 Myosin head (motor domain) RskA PF10099.9 CDJ38535.1 - 0.0003 21.1 21.0 0.0003 21.1 21.0 3.4 2 1 1 3 3 1 1 Anti-sigma-K factor rskA Activator_LAG-3 PF11498.8 CDJ38535.1 - 0.0026 16.8 19.8 0.0026 16.8 19.8 1.6 2 0 0 2 2 1 1 Transcriptional activator LAG-3 Suf PF05843.14 CDJ38535.1 - 0.0043 17.1 7.1 0.0043 17.1 7.1 1.5 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) RAB3GAP2_N PF14655.6 CDJ38535.1 - 0.01 15.1 4.3 0.016 14.5 4.3 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus MecA PF05389.12 CDJ38535.1 - 0.02 14.6 0.2 0.027 14.1 0.2 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF2722 PF10846.8 CDJ38535.1 - 0.097 11.6 22.6 0.16 10.8 22.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 CDJ38535.1 - 0.16 11.0 6.2 0.19 10.7 6.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rxt3 PF08642.10 CDJ38535.1 - 0.18 12.6 2.8 6.4 7.6 2.0 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 RNA_pol_Rbc25 PF08292.12 CDJ38535.1 - 0.28 11.4 2.7 0.54 10.5 2.7 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Spt20 PF12090.8 CDJ38535.1 - 0.32 10.6 30.2 0.63 9.6 30.2 1.4 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ38535.1 - 0.33 11.9 8.0 0.67 10.9 8.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TERB2 PF15101.6 CDJ38535.1 - 1.1 9.2 10.0 2.2 8.3 10.0 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PIP5K PF01504.18 CDJ38535.1 - 1.5 8.0 5.9 2.2 7.4 5.4 1.3 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase UPF0560 PF10577.9 CDJ38535.1 - 2.2 6.7 10.9 3.7 5.9 10.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pex14_N PF04695.13 CDJ38535.1 - 4.7 7.8 26.7 3.1 8.4 17.4 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 CDJ38535.1 - 5.5 5.1 17.2 8.4 4.5 17.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.10 CDJ38535.1 - 5.9 5.5 32.7 0.072 11.8 20.3 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal EPL1 PF10513.9 CDJ38536.1 - 0.62 10.4 43.2 4.1 7.8 0.2 4.7 5 0 0 5 5 5 0 Enhancer of polycomb-like Mpp10 PF04006.12 CDJ38536.1 - 4 5.8 39.1 0.071 11.5 10.2 4.0 4 0 0 4 4 4 0 Mpp10 protein K_channel_TID PF07941.11 CDJ38538.1 - 1 9.8 17.7 1 9.9 13.6 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Dala_Dala_lig_N PF01820.21 CDJ38539.1 - 0.24 11.9 5.8 3.9 8.0 5.8 2.5 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF4484 PF14831.6 CDJ38539.1 - 0.3 11.1 12.1 0.077 13.0 3.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) AP-5_subunit_s1 PF15001.6 CDJ38539.1 - 2.7 7.9 16.9 0.74 9.8 8.4 2.2 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 CPSF100_C PF13299.6 CDJ38539.1 - 3.6 7.7 12.6 4.2 7.5 6.0 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Pet20 PF08692.10 CDJ38539.1 - 4 8.2 6.1 6.2 7.5 1.5 2.3 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Band_3_cyto PF07565.13 CDJ38539.1 - 6.3 6.5 15.6 3 7.6 7.3 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Peptidase_S8 PF00082.22 CDJ38542.1 - 1.3e-08 34.5 0.0 1.5e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Subtilase family CcmD PF04995.14 CDJ38542.1 - 0.61 10.2 5.0 1.2 9.2 5.0 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) TFIIA PF03153.13 CDJ38543.1 - 0.0024 17.9 40.6 0.0031 17.6 40.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SART-1 PF03343.13 CDJ38543.1 - 0.62 8.6 16.4 0.84 8.1 16.4 1.2 1 0 0 1 1 1 0 SART-1 family EphA2_TM PF14575.6 CDJ38543.1 - 4.2 8.3 4.9 2.6 9.0 0.7 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4207 PF13904.6 CDJ38543.1 - 4.9 6.8 25.3 9.4 5.8 18.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) DUF5327 PF17261.2 CDJ38543.1 - 5.5 7.8 21.3 7.8 7.3 12.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Eapp_C PF10238.9 CDJ38543.1 - 8.2 6.5 16.5 1.9 8.5 7.1 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Proteasome PF00227.26 CDJ38545.1 - 0.0011 18.5 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Phostensin_N PF13916.6 CDJ38547.1 - 0.0086 16.4 1.4 0.0086 16.4 1.4 8.0 8 0 0 8 8 8 1 PP1-regulatory protein, Phostensin N-terminal SUIM_assoc PF16619.5 CDJ38547.1 - 0.076 13.1 0.2 0.076 13.1 0.2 10.0 9 1 0 9 9 9 0 Unstructured region C-term to UIM in Ataxin3 Proteasome PF00227.26 CDJ38548.1 - 1.6e-19 70.2 0.0 1.8e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CcmD PF04995.14 CDJ38550.1 - 0.0062 16.6 2.2 0.014 15.5 2.2 1.5 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) Spt20 PF12090.8 CDJ38550.1 - 0.9 9.1 10.0 1.2 8.7 10.0 1.3 1 0 0 1 1 1 0 Spt20 family AAA_lid_11 PF18198.1 CDJ38551.1 - 1.4e-16 60.8 0.0 2.9e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_9 PF12781.7 CDJ38551.1 - 7.4e-11 41.6 3.6 1.4e-10 40.6 3.6 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region RskA PF10099.9 CDJ38552.1 - 0.017 15.4 0.1 0.017 15.4 0.1 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3824 PF12868.7 CDJ38552.1 - 0.82 10.3 3.7 0.35 11.5 1.4 1.5 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Iso_dh PF00180.20 CDJ38553.1 - 3.3e-20 72.5 0.0 4.3e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-RING_2 PF13639.6 CDJ38554.1 - 1.2e-08 35.2 2.5 1.2e-08 35.2 2.5 2.6 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 CDJ38554.1 - 5e-08 33.1 2.9 1.2e-07 31.9 2.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ38554.1 - 1.2e-06 28.3 1.4 1.2e-06 28.3 1.4 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ38554.1 - 4e-06 26.6 3.7 4e-06 26.6 3.7 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ38554.1 - 9.2e-06 25.3 2.0 9.2e-06 25.3 2.0 2.6 3 0 0 3 3 3 1 RING-like zinc finger zf-ANAPC11 PF12861.7 CDJ38554.1 - 0.00016 21.6 1.4 0.00031 20.7 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CDJ38554.1 - 0.00027 20.8 1.5 0.00027 20.8 1.5 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ38554.1 - 0.001 19.0 0.4 0.001 19.0 0.4 2.8 2 2 0 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CDJ38554.1 - 0.0012 18.4 1.8 0.0012 18.4 1.8 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CDJ38554.1 - 0.24 11.6 4.5 0.9 9.8 4.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain TMEM154 PF15102.6 CDJ38555.1 - 0.00046 20.1 0.9 0.00052 19.9 0.0 1.4 2 0 0 2 2 2 1 TMEM154 protein family DUF4667 PF15700.5 CDJ38555.1 - 0.0011 19.1 0.5 0.0013 18.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) Sporozoite_P67 PF05642.11 CDJ38555.1 - 0.019 13.1 7.1 0.024 12.8 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BatD PF13584.6 CDJ38555.1 - 0.028 13.2 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance TraT PF05818.12 CDJ38555.1 - 0.098 12.3 1.5 0.11 12.1 0.6 1.4 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein Macoilin PF09726.9 CDJ38555.1 - 0.25 9.8 1.5 0.33 9.4 1.5 1.1 1 0 0 1 1 1 0 Macoilin family LCE6A PF15858.5 CDJ38555.1 - 0.44 11.3 12.1 0.16 12.8 2.4 2.3 2 0 0 2 2 2 0 Late cornified envelope protein 6A family DUF3446 PF11928.8 CDJ38555.1 - 6.4 7.2 20.4 0.84 10.0 7.9 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 CDJ38555.1 - 6.5 6.3 15.2 11 5.6 15.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4644 PF15486.6 CDJ38555.1 - 8.2 6.2 12.3 5.5 6.7 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) F-box-like PF12937.7 CDJ38556.1 - 6e-06 26.1 0.3 1.4e-05 24.9 0.3 1.7 1 0 0 1 1 1 1 F-box-like Exonuc_VII_L PF02601.15 CDJ38556.1 - 0.0027 17.4 8.5 0.0042 16.7 8.5 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit F-box PF00646.33 CDJ38556.1 - 0.0067 16.3 2.3 0.01 15.7 0.1 2.3 2 0 0 2 2 2 1 F-box domain PI3K_1B_p101 PF10486.9 CDJ38556.1 - 0.033 12.0 15.3 0.067 11.0 15.3 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Draxin PF15550.6 CDJ38556.1 - 8.5 6.1 13.7 16 5.2 13.7 1.5 1 0 0 1 1 1 0 Draxin Cofilin_ADF PF00241.20 CDJ38558.1 - 0.076 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Ribosomal_S9 PF00380.19 CDJ38559.1 - 3.8e-35 121.0 0.6 3.8e-35 121.0 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S9/S16 Tli4_C PF18426.1 CDJ38559.1 - 0.078 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Tle cognate immunity protein 4 C-terminal domain SLC12 PF03522.15 CDJ38560.1 - 0.69 8.9 3.6 1.1 8.3 3.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SUIM_assoc PF16619.5 CDJ38561.1 - 0.007 16.4 3.3 0.007 16.4 3.3 6.0 3 2 2 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 DUF3357 PF11837.8 CDJ38561.1 - 0.11 13.0 4.9 0.99 9.9 0.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) DUF4746 PF15928.5 CDJ38561.1 - 1.5 8.1 0.0 1.5 8.1 0.0 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4746) Spt20 PF12090.8 CDJ38563.1 - 0.055 13.1 5.0 0.062 12.9 5.0 1.1 1 0 0 1 1 1 0 Spt20 family Sporozoite_P67 PF05642.11 CDJ38563.1 - 4.6 5.2 9.1 5 5.1 9.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen F-actin_cap_A PF01267.17 CDJ38564.1 - 5.6e-15 55.5 0.4 9.9e-15 54.7 0.4 1.4 1 1 0 1 1 1 1 F-actin capping protein alpha subunit SID-1_RNA_chan PF13965.6 CDJ38564.1 - 0.0015 17.1 2.8 0.0018 16.8 2.8 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 RF-1 PF00472.20 CDJ38564.1 - 0.012 15.6 4.3 0.012 15.6 4.3 1.7 2 0 0 2 2 2 0 RF-1 domain ANAPC1 PF12859.7 CDJ38564.1 - 0.044 14.3 0.1 0.083 13.5 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Spt20 PF12090.8 CDJ38564.1 - 0.076 12.6 7.4 0.12 12.0 7.4 1.3 1 0 0 1 1 1 0 Spt20 family TLP-20 PF06088.11 CDJ38564.1 - 0.32 10.9 4.7 0.61 10.0 4.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CAF-1_p150 PF11600.8 CDJ38564.1 - 0.45 10.2 19.6 2.4 7.8 17.8 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Afi1 PF07792.12 CDJ38564.1 - 3.8 8.0 8.0 1.1 9.8 5.0 1.5 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2722 PF10846.8 CDJ38565.1 - 1.5e-06 27.5 12.3 1.5e-06 27.5 12.3 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ38565.1 - 0.0067 16.8 4.5 0.0067 16.8 4.5 2.3 2 0 0 2 2 2 1 Enhancer of polycomb-like SpoIIP PF07454.11 CDJ38565.1 - 2.7 7.4 18.7 0.19 11.1 9.9 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CTNNB1_binding PF08347.11 CDJ38565.1 - 3 8.0 16.6 2.6 8.2 7.8 2.2 2 0 0 2 2 2 0 N-terminal CTNNB1 binding Zip PF02535.22 CDJ38565.1 - 3.4 6.8 8.8 0.74 9.0 1.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Band_3_cyto PF07565.13 CDJ38565.1 - 5.4 6.7 21.3 2 8.2 10.6 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain EOS1 PF12326.8 CDJ38565.1 - 9.6 6.1 12.8 41 4.1 0.1 2.2 2 0 0 2 2 2 0 N-glycosylation protein Kelch_1 PF01344.25 CDJ38566.1 - 1.1e-19 69.7 0.0 2.5e-10 39.8 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CDJ38566.1 - 1.5e-10 40.9 0.0 4.7e-07 29.8 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CDJ38566.1 - 0.0007 19.5 0.0 0.005 16.8 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 CDJ38566.1 - 0.017 15.1 0.0 9.1 6.4 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 CDJ38566.1 - 0.05 13.9 0.1 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain FAM76 PF16046.5 CDJ38567.1 - 8.1e-11 41.8 20.4 8.1e-11 41.8 20.4 2.7 2 1 0 2 2 2 1 FAM76 protein DZR PF12773.7 CDJ38567.1 - 4.3 7.4 12.7 46 4.1 10.4 2.8 2 1 0 2 2 2 0 Double zinc ribbon PAT1 PF09770.9 CDJ38568.1 - 1.9 6.7 31.8 2.4 6.3 31.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RskA PF10099.9 CDJ38569.1 - 0.019 15.3 17.9 0.027 14.8 17.9 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF755 PF05501.11 CDJ38569.1 - 0.029 14.7 13.9 0.061 13.6 13.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Sec3_C PF09763.9 CDJ38569.1 - 0.035 12.5 0.9 0.034 12.6 0.9 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF1635 PF07795.11 CDJ38569.1 - 0.12 12.2 7.0 0.17 11.7 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) ATG22 PF11700.8 CDJ38569.1 - 0.2 10.3 1.1 0.22 10.1 1.1 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like BPS1 PF05633.11 CDJ38569.1 - 0.37 9.8 5.8 0.46 9.4 5.8 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related Presenilin PF01080.17 CDJ38569.1 - 0.66 8.7 4.2 0.65 8.7 4.2 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CDJ38569.1 - 2 7.2 6.9 2.3 6.9 6.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIA PF03153.13 CDJ38569.1 - 5.6 6.9 14.5 6.7 6.6 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CorA PF01544.18 CDJ38570.1 - 2.1e-07 30.6 0.1 4e-07 29.6 0.1 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein HxlR PF01638.17 CDJ38570.1 - 0.018 14.8 0.1 0.041 13.7 0.1 1.6 1 1 0 1 1 1 0 HxlR-like helix-turn-helix DUF202 PF02656.15 CDJ38570.1 - 0.032 14.7 2.3 0.032 14.7 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF2231 PF09990.9 CDJ38570.1 - 0.088 13.3 2.5 0.16 12.4 2.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) SesA PF17107.5 CDJ38570.1 - 0.11 12.7 1.6 0.22 11.7 0.2 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Kringle PF00051.18 CDJ38571.1 - 4.3e-13 49.4 2.5 4.3e-13 49.4 2.5 2.7 2 0 0 2 2 2 1 Kringle domain MAR_sialic_bdg PF10564.9 CDJ38571.1 - 2.9e-09 36.9 7.9 0.001 19.1 0.0 5.0 5 0 0 5 5 5 2 Sialic-acid binding micronemal adhesive repeat K_trans PF02705.16 CDJ38571.1 - 0.043 12.3 0.5 0.065 11.7 0.5 1.1 1 0 0 1 1 1 0 K+ potassium transporter COX14 PF14880.6 CDJ38571.1 - 0.2 11.5 4.1 0.6 10.0 4.1 1.8 1 0 0 1 1 1 0 Cytochrome oxidase c assembly PalH PF08733.10 CDJ38571.1 - 0.24 10.3 0.6 0.47 9.4 0.6 1.3 1 0 0 1 1 1 0 PalH/RIM21 Presenilin PF01080.17 CDJ38571.1 - 2.1 7.1 10.3 1.1 8.0 0.5 2.2 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 CDJ38571.1 - 3 7.8 5.6 13 5.8 0.6 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region GEN1_C PF18380.1 CDJ38571.1 - 6.3 7.8 8.1 2.8 8.9 3.3 2.3 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Pkinase PF00069.25 CDJ38572.1 - 4.3e-75 252.5 0.0 6.3e-75 251.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ38572.1 - 1.8e-38 132.3 0.0 3.2e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CDJ38572.1 - 1e-14 54.9 0.0 1.7e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 CDJ38572.1 - 0.00016 21.1 0.2 0.0046 16.3 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CDJ38572.1 - 0.00019 20.3 0.0 0.00071 18.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 CDJ38572.1 - 0.00056 19.6 1.0 0.0011 18.6 1.0 1.4 1 0 0 1 1 1 1 RIO1 family PH_8 PF15409.6 CDJ38572.1 - 0.00073 19.8 0.1 0.002 18.3 0.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain Kdo PF06293.14 CDJ38572.1 - 0.0015 17.9 0.5 0.0015 17.9 0.5 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 CDJ38572.1 - 0.0092 15.0 0.1 0.013 14.4 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase PH_11 PF15413.6 CDJ38572.1 - 0.17 12.3 0.1 4.5 7.7 0.1 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain Lar_restr_allev PF14354.6 CDJ38572.1 - 1.6 9.2 9.0 2.8 8.4 4.2 4.3 3 0 0 3 3 2 0 Restriction alleviation protein Lar zf-RING_7 PF02591.15 CDJ38572.1 - 2.6 8.3 5.3 3.9 7.7 0.0 3.1 3 0 0 3 3 3 0 C4-type zinc ribbon domain RskA PF10099.9 CDJ38576.1 - 0.054 13.8 21.5 5.9 7.2 21.6 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA LRR_4 PF12799.7 CDJ38576.1 - 0.22 12.0 9.5 20 5.8 0.4 4.4 2 2 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ38576.1 - 4.9 7.0 6.4 5.5 6.8 0.2 3.2 3 1 0 3 3 3 0 Leucine rich repeat PRP3 PF08572.10 CDJ38577.1 - 4.3e-58 196.7 14.7 4.3e-58 196.7 14.7 3.5 3 1 1 4 4 4 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CDJ38577.1 - 1.5e-33 116.0 0.2 1.5e-33 116.0 0.2 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF1115) Gp_dh_C PF02800.20 CDJ38578.1 - 9.5e-55 184.5 0.0 4.3e-53 179.1 0.0 2.3 1 1 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CDJ38578.1 - 1.5e-34 118.3 0.0 2.8e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CDJ38578.1 - 0.044 13.1 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 CDJ38578.1 - 0.16 12.1 0.6 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus MIF4G PF02854.19 CDJ38579.1 - 1.7e-35 122.6 3.4 3e-35 121.8 3.4 1.3 1 0 0 1 1 1 1 MIF4G domain Helicase_C PF00271.31 CDJ38580.1 - 1.6e-09 38.1 0.0 2.1e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NodZ PF05830.11 CDJ38580.1 - 0.13 11.1 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) PAN_4 PF14295.6 CDJ38581.1 - 2.3e-05 24.2 0.6 4.3e-05 23.3 0.6 1.4 1 0 0 1 1 1 1 PAN domain DivIC PF04977.15 CDJ38582.1 - 2 8.3 10.9 5.9 6.7 10.9 1.8 1 0 0 1 1 1 0 Septum formation initiator Eapp_C PF10238.9 CDJ38583.1 - 0.11 12.6 9.5 0.13 12.3 9.5 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein ANAPC_CDC26 PF10471.9 CDJ38583.1 - 5.5 7.9 33.3 3.8e+02 2.0 33.3 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 NOT2_3_5 PF04153.18 CDJ38584.1 - 3.2e-15 56.4 8.7 1.9e-14 53.8 0.1 2.8 2 1 0 2 2 2 2 NOT2 / NOT3 / NOT5 family Peptidase_C1 PF00112.23 CDJ38585.1 - 1e-16 61.7 6.1 3.1e-13 50.3 2.1 2.9 1 1 2 3 3 3 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ38585.1 - 0.071 11.9 1.5 0.098 11.4 1.5 1.1 1 0 0 1 1 1 0 Peptidase C1-like family DUF5437 PF17505.2 CDJ38586.1 - 1.2 9.2 6.3 1.1 9.4 4.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5437) Prp18 PF02840.15 CDJ38587.1 - 9.1e-56 187.9 0.3 9.1e-56 187.9 0.3 2.4 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 CDJ38587.1 - 2.9e-12 45.9 0.4 2.9e-12 45.9 0.4 2.4 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like NUC130_3NT PF08158.12 CDJ38587.1 - 0.097 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 NUC130/3NT domain RimM PF01782.18 CDJ38588.1 - 1.5e-10 41.2 0.0 3.5e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 RimM N-terminal domain Apt1 PF10351.9 CDJ38588.1 - 4.6 6.0 10.2 1.8 7.3 7.4 1.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain YEATS PF03366.16 CDJ38590.1 - 4.2e-08 33.0 0.0 6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 YEATS family TIR PF01582.20 CDJ38590.1 - 0.098 12.4 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 TIR domain AAA_25 PF13481.6 CDJ38591.1 - 0.019 14.5 0.1 0.054 13.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain Smr PF01713.21 CDJ38591.1 - 0.023 15.0 0.2 0.3 11.5 0.0 2.8 3 0 0 3 3 3 0 Smr domain SUIM_assoc PF16619.5 CDJ38591.1 - 0.39 10.8 60.4 1.4 9.1 3.2 5.7 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Ribul_P_3_epim PF00834.19 CDJ38593.1 - 9.5e-26 90.4 0.1 1.2e-25 90.1 0.1 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family His_biosynth PF00977.21 CDJ38593.1 - 0.002 17.6 0.1 0.0023 17.4 0.1 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF561 PF04481.12 CDJ38593.1 - 0.037 13.2 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) QRPTase_C PF01729.19 CDJ38593.1 - 0.061 13.1 0.0 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Helicase_C PF00271.31 CDJ38595.1 - 1.9e-09 37.9 0.0 4e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ38595.1 - 1.2e-07 32.1 0.1 2.5e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CDJ38595.1 - 3e-07 30.4 0.2 5.9e-07 29.4 0.2 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CDJ38595.1 - 1.4e-05 24.9 0.1 1.4e-05 24.9 0.1 1.7 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 CDJ38595.1 - 1.8e-05 25.1 0.1 4.1e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ38595.1 - 0.00068 19.7 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 CDJ38595.1 - 0.0021 18.4 0.2 0.0091 16.4 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 CDJ38595.1 - 0.0025 17.4 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region SRP54 PF00448.22 CDJ38595.1 - 0.0056 16.3 0.4 0.016 14.8 0.4 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain PhoH PF02562.16 CDJ38595.1 - 0.0074 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_33 PF13671.6 CDJ38595.1 - 0.012 15.8 0.0 0.036 14.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CDJ38595.1 - 0.016 14.7 0.2 0.065 12.8 0.1 2.2 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 CDJ38595.1 - 0.018 14.1 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 CDJ38595.1 - 0.027 15.0 0.4 0.86 10.1 0.1 2.4 1 1 0 2 2 2 0 ABC transporter DUF2075 PF09848.9 CDJ38595.1 - 0.035 13.4 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CDJ38595.1 - 0.038 13.9 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain DAP3 PF10236.9 CDJ38595.1 - 0.054 12.7 0.1 0.098 11.8 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TrwB_AAD_bind PF10412.9 CDJ38595.1 - 0.086 11.7 0.2 0.14 11.0 0.2 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.6 CDJ38595.1 - 0.099 12.7 0.1 0.81 9.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDJ38595.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 CDJ38595.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 CDJ38595.1 - 0.18 11.3 0.0 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.6 CDJ38595.1 - 0.18 12.3 0.1 0.48 10.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain Sin_N PF04801.13 CDJ38607.1 - 2.5e-46 158.8 32.9 3.2e-43 148.5 28.6 2.2 1 1 1 2 2 2 2 Sin-like protein conserved region SUIM_assoc PF16619.5 CDJ38607.1 - 0.03 14.4 3.5 0.03 14.4 3.5 4.9 3 1 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 ANAPC_CDC26 PF10471.9 CDJ38607.1 - 0.083 13.7 41.0 0.075 13.9 2.3 4.3 4 1 0 4 4 4 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CDJ38607.1 - 0.19 11.3 31.1 0.59 9.7 3.4 3.2 3 0 0 3 3 3 0 Spt20 family DUF4834 PF16118.5 CDJ38607.1 - 0.61 11.1 12.1 1.3 10.0 0.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF2877 PF11392.8 CDJ38607.1 - 3.1 8.6 5.6 1.7 9.4 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2877) DUF2371 PF10177.9 CDJ38607.1 - 4.9 7.3 5.3 19 5.4 5.3 2.0 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) BSMAP PF12280.8 CDJ38607.1 - 7.3 6.8 22.7 0.052 13.8 3.5 3.2 2 1 1 3 3 3 0 Brain specific membrane anchored protein DUF5345 PF17280.2 CDJ38623.1 - 0.081 12.9 2.2 0.12 12.4 2.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5345) WTX PF09422.10 CDJ38623.1 - 0.088 11.9 1.3 0.087 11.9 1.3 1.0 1 0 0 1 1 1 0 WTX protein FBP_C PF16571.5 CDJ38623.1 - 0.18 11.3 3.6 0.29 10.7 3.3 1.4 1 1 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger CcmD PF04995.14 CDJ38623.1 - 7.5 6.7 7.4 17 5.6 7.4 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Cullin PF00888.22 CDJ38624.1 - 5e-42 144.3 1.5 8.1e-42 143.6 1.5 1.3 1 0 0 1 1 1 1 Cullin family NifU PF01106.17 CDJ38626.1 - 0.00036 20.6 0.0 0.00091 19.3 0.0 1.7 1 1 0 1 1 1 1 NifU-like domain Ribosomal_L19e PF01280.20 CDJ38627.1 - 8.7e-43 145.8 10.3 8.7e-43 145.8 10.3 2.0 1 1 1 2 2 2 1 Ribosomal protein L19e YhzD PF14120.6 CDJ38627.1 - 2.9 8.1 6.0 2.2 8.4 3.5 2.0 2 0 0 2 2 2 0 YhzD-like protein adh_short PF00106.25 CDJ38629.1 - 1.5e-27 96.3 1.2 1.9e-22 79.7 1.3 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ38629.1 - 1.6e-20 73.7 1.6 4e-17 62.6 0.9 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ38629.1 - 2.6e-10 40.5 0.3 4.8e-10 39.6 0.3 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ38629.1 - 0.029 13.8 0.1 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PNPase PF03726.14 CDJ38629.1 - 0.081 13.4 0.2 15 6.2 0.0 2.3 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain H_PPase PF03030.16 CDJ38638.1 - 7.5e-50 170.3 11.5 6.8e-48 163.8 2.4 2.5 1 1 2 3 3 3 2 Inorganic H+ pyrophosphatase DUF1645 PF07816.11 CDJ38650.1 - 0.0094 16.5 11.9 0.0094 16.5 11.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1645) EMC3_TMCO1 PF01956.16 CDJ38650.1 - 0.0094 15.7 4.6 0.013 15.2 4.6 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF572 PF04502.13 CDJ38650.1 - 0.072 12.7 9.3 0.093 12.3 9.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Med15 PF09606.10 CDJ38650.1 - 0.24 10.0 29.7 0.38 9.4 29.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2052 PF09747.9 CDJ38650.1 - 0.26 11.4 11.5 0.44 10.7 11.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Lin-8 PF03353.15 CDJ38650.1 - 0.4 10.2 20.6 0.7 9.4 20.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Fmp27_WPPW PF10359.9 CDJ38650.1 - 0.43 9.4 15.2 0.59 8.9 15.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Serinc PF03348.15 CDJ38650.1 - 0.56 9.1 6.5 27 3.5 7.1 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) eIF3_subunit PF08597.10 CDJ38650.1 - 0.7 9.8 11.4 1.3 8.9 11.4 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Ureide_permease PF07168.11 CDJ38650.1 - 0.75 8.5 3.4 3 6.5 3.1 1.9 2 0 0 2 2 2 0 Ureide permease Peptidase_S64 PF08192.11 CDJ38650.1 - 1.2 7.6 15.8 1.7 7.1 15.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 WASH-7_C PF14746.6 CDJ38650.1 - 2.1 8.0 10.0 3.9 7.1 10.0 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Sec62 PF03839.16 CDJ38650.1 - 2.1 7.8 6.6 3.4 7.1 6.6 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 CSG2 PF16965.5 CDJ38650.1 - 2.2 7.1 4.1 4.2 6.2 4.1 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator Mcm10 PF09332.11 CDJ38650.1 - 2.5 7.5 19.6 3.9 6.8 19.6 1.3 1 0 0 1 1 1 0 Mcm10 replication factor PAT1 PF09770.9 CDJ38650.1 - 2.6 6.2 21.3 3.5 5.8 21.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Connexin PF00029.19 CDJ38650.1 - 2.6 7.7 6.7 4.4 7.0 6.7 1.3 1 0 0 1 1 1 0 Connexin SID-1_RNA_chan PF13965.6 CDJ38650.1 - 2.8 6.2 3.5 4 5.7 3.5 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Cellulose_synt PF03552.14 CDJ38650.1 - 3.1 6.2 3.4 4 5.8 3.4 1.1 1 0 0 1 1 1 0 Cellulose synthase V_ATPase_I PF01496.19 CDJ38650.1 - 3.2 5.5 9.2 4 5.2 9.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Folate_carrier PF01770.18 CDJ38650.1 - 3.4 6.3 5.7 7 5.3 5.7 1.5 1 0 0 1 1 1 0 Reduced folate carrier CLN3 PF02487.17 CDJ38650.1 - 4.8 6.1 7.1 8.8 5.3 7.1 1.4 1 0 0 1 1 1 0 CLN3 protein TAF4 PF05236.14 CDJ38650.1 - 5.6 6.6 19.8 1.2e+02 2.3 19.8 2.3 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Macoilin PF09726.9 CDJ38651.1 - 0.011 14.3 4.8 0.016 13.8 4.8 1.3 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ38651.1 - 0.19 10.6 4.9 0.2 10.4 4.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ38651.1 - 1.9 8.3 14.5 2.5 8.0 14.5 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 CDJ38651.1 - 2.3 7.3 13.3 2.9 7.0 13.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4692 PF15763.5 CDJ38651.1 - 2.6 8.5 20.4 0.75 10.3 6.1 2.2 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) SR-25 PF10500.9 CDJ38651.1 - 3.3 7.3 24.9 0.31 10.6 6.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.19 CDJ38657.1 - 0.024 15.2 0.9 0.033 14.8 0.9 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Med15 PF09606.10 CDJ38657.1 - 0.85 8.2 8.0 1.1 7.9 8.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Methyltransf_9 PF08003.11 CDJ38664.1 - 0.12 11.3 5.2 0.18 10.7 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TFIIA PF03153.13 CDJ38664.1 - 4.7 7.1 39.8 6.5 6.6 39.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Baculo_p24 PF05073.12 CDJ38664.1 - 5 6.9 8.3 4.7 7.0 7.4 1.3 1 1 0 1 1 1 0 Baculovirus P24 capsid protein SR-25 PF10500.9 CDJ38668.1 - 0.00038 20.1 4.5 0.00049 19.8 4.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ38668.1 - 0.04 14.1 9.6 0.044 14.0 9.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TFIIA PF03153.13 CDJ38668.1 - 0.99 9.3 24.0 1.2 9.0 24.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 CDJ38668.1 - 1.2 9.0 10.6 1.4 8.8 10.6 1.1 1 0 0 1 1 1 0 Velvet factor Presenilin PF01080.17 CDJ38668.1 - 1.9 7.2 8.5 2 7.1 8.5 1.1 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CDJ38668.1 - 3.8 4.5 9.8 3.9 4.5 9.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF-3_zeta PF05091.12 CDJ38668.1 - 4.1 6.3 8.5 4.9 6.0 8.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ndc1_Nup PF09531.10 CDJ38668.1 - 6.1 5.4 8.3 6.4 5.3 8.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRM_1 PF00076.22 CDJ38676.1 - 1.6e-05 24.7 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ38676.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CDJ38676.1 - 0.056 13.0 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PPTA PF01239.22 CDJ38679.1 - 3.4e-14 52.0 17.4 4.9e-07 29.3 1.4 4.0 5 0 0 5 5 3 3 Protein prenyltransferase alpha subunit repeat RskA PF10099.9 CDJ38679.1 - 9.4e-06 26.0 15.2 2.6e-05 24.6 1.8 2.7 2 1 0 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ38679.1 - 0.00059 19.9 29.6 0.00081 19.5 29.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 CDJ38679.1 - 0.0027 17.7 10.0 0.0036 17.3 10.0 1.1 1 0 0 1 1 1 1 Velvet factor Tau95_N PF17682.1 CDJ38679.1 - 0.0049 17.1 2.8 0.0092 16.2 2.8 1.4 1 0 0 1 1 1 1 Tau95 Triple barrel domain Presenilin PF01080.17 CDJ38679.1 - 0.013 14.3 7.6 0.015 14.1 7.6 1.2 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ38679.1 - 0.014 14.5 11.3 0.015 14.3 11.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ38679.1 - 0.018 13.0 7.1 0.021 12.8 7.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAT1 PF09770.9 CDJ38679.1 - 0.034 12.4 19.0 0.037 12.3 19.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EOS1 PF12326.8 CDJ38679.1 - 0.067 13.1 2.1 0.1 12.5 2.1 1.4 1 0 0 1 1 1 0 N-glycosylation protein SpoIIP PF07454.11 CDJ38679.1 - 0.096 12.1 7.7 0.14 11.6 7.7 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) OATP PF03137.20 CDJ38679.1 - 0.097 10.9 3.1 0.13 10.5 3.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ALMT PF11744.8 CDJ38679.1 - 0.12 11.2 6.5 0.13 11.1 6.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter TFB6 PF17110.5 CDJ38679.1 - 0.16 11.7 6.7 0.27 11.0 6.7 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Dpy19 PF10034.9 CDJ38679.1 - 0.16 10.1 1.2 0.21 9.7 1.2 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Neur_chan_memb PF02932.16 CDJ38679.1 - 0.17 11.9 5.3 0.22 11.6 5.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 CDJ38679.1 - 0.18 11.5 4.8 0.27 10.9 4.8 1.3 1 0 0 1 1 1 0 Connexin Band_3_cyto PF07565.13 CDJ38679.1 - 0.31 10.8 8.2 0.44 10.3 8.2 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FTO_NTD PF12933.7 CDJ38679.1 - 0.36 10.0 11.3 0.065 12.5 7.8 1.5 2 0 0 2 2 2 0 FTO catalytic domain CLN3 PF02487.17 CDJ38679.1 - 0.42 9.6 6.0 0.54 9.2 6.0 1.2 1 0 0 1 1 1 0 CLN3 protein UPF0560 PF10577.9 CDJ38679.1 - 0.76 8.2 14.6 1.1 7.7 14.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TPR_17 PF13431.6 CDJ38679.1 - 0.84 10.2 0.1 0.84 10.2 0.1 3.7 3 1 0 3 3 2 0 Tetratricopeptide repeat SID-1_RNA_chan PF13965.6 CDJ38679.1 - 0.84 8.0 2.9 1 7.7 2.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4834 PF16118.5 CDJ38679.1 - 1.3 10.0 13.6 2.7 9.0 12.9 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) Myc_N PF01056.18 CDJ38679.1 - 1.4 8.8 11.3 1.3 8.9 10.3 1.4 1 1 0 1 1 1 0 Myc amino-terminal region RR_TM4-6 PF06459.12 CDJ38679.1 - 1.5 8.6 13.2 0.11 12.3 8.6 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 LMBR1 PF04791.16 CDJ38679.1 - 2.4 7.0 8.9 3.3 6.5 8.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF853 PF05872.12 CDJ38679.1 - 2.5 6.6 14.8 0.15 10.7 8.9 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) O-antigen_lig PF13425.6 CDJ38679.1 - 2.5 6.8 3.6 3.2 6.4 3.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Folate_carrier PF01770.18 CDJ38679.1 - 2.5 6.7 6.4 3.5 6.3 6.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier LRRC37AB_C PF14914.6 CDJ38679.1 - 3.5 7.5 13.2 7.4 6.5 13.2 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain FAM176 PF14851.6 CDJ38679.1 - 3.8 7.2 8.9 0.43 10.2 4.5 1.7 2 0 0 2 2 2 0 FAM176 family AIF_C PF14721.6 CDJ38679.1 - 5.1 7.5 9.7 1.6 9.1 6.5 1.8 2 0 0 2 2 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TERB2 PF15101.6 CDJ38679.1 - 5.6 7.0 20.0 0.26 11.3 14.1 1.8 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Scs3p PF10261.9 CDJ38679.1 - 6 6.3 6.9 12 5.3 6.9 1.6 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Afi1 PF07792.12 CDJ38679.1 - 7.7 7.0 13.2 13 6.3 13.2 1.4 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DDRGK PF09756.9 CDJ38679.1 - 9.7 5.7 21.0 1.1 8.8 16.4 1.7 2 0 0 2 2 2 0 DDRGK domain eIF-5a PF01287.20 CDJ38681.1 - 6.8e-25 87.0 0.1 9.8e-25 86.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CDJ38681.1 - 0.0032 17.5 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain DUF1840 PF08895.11 CDJ38683.1 - 0.061 13.7 0.3 0.13 12.6 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) SPX PF03105.19 CDJ38683.1 - 2 8.3 7.7 2.7 7.8 7.7 1.1 1 0 0 1 1 1 0 SPX domain Edc3_linker PF16598.5 CDJ38683.1 - 4.5 8.0 11.3 0.78 10.4 7.0 1.9 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 DUF2076 PF09849.9 CDJ38686.1 - 0.00041 20.5 4.5 0.00057 20.0 4.5 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) RskA PF10099.9 CDJ38686.1 - 0.054 13.8 9.0 0.099 12.9 8.9 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA CSRNP_N PF16019.5 CDJ38686.1 - 7.1 6.5 6.4 1.2 9.0 2.6 1.8 2 1 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Pkinase PF00069.25 CDJ38687.1 - 4.5e-60 203.3 0.0 6.6e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ38687.1 - 3e-30 105.4 0.0 4.5e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ38687.1 - 0.021 14.1 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 CDJ38687.1 - 0.15 10.8 0.0 0.15 10.8 0.0 2.7 2 1 0 2 2 2 0 Fungal protein kinase Tox-GHH2 PF15635.6 CDJ38687.1 - 1.1 9.8 8.1 0.064 13.8 1.6 2.3 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 DUF3649 PF12365.8 CDJ38688.1 - 0.066 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) RNA_pol_Rpb8 PF03870.15 CDJ38689.1 - 4.2e-38 130.7 0.0 4.8e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CDJ38689.1 - 4.5e-06 26.7 0.0 2.9e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 DNA-directed RNA polymerase, subunit G SAPS PF04499.15 CDJ38693.1 - 1.2 7.8 4.9 1.8 7.2 4.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein V_ATPase_I PF01496.19 CDJ38693.1 - 3.8 5.3 3.9 5.9 4.7 3.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SUIM_assoc PF16619.5 CDJ38693.1 - 6.6 6.9 25.2 0.15 12.1 0.7 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PAP1 PF08601.10 CDJ38704.1 - 0.087 12.5 7.0 0.15 11.8 7.0 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 Vps16_C PF04840.12 CDJ38705.1 - 1.2e-25 90.3 0.2 5.5e-24 84.8 0.0 2.3 1 1 1 2 2 2 2 Vps16, C-terminal region Sigma54_activ_2 PF14532.6 CDJ38705.1 - 0.11 12.7 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain zf-P11 PF03854.14 CDJ38706.1 - 0.094 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 P-11 zinc finger AAA_22 PF13401.6 CDJ38707.1 - 0.00037 20.8 0.1 0.0011 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CDJ38707.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Glug PF07581.12 CDJ38707.1 - 0.023 15.1 1.3 0.75 10.3 0.0 2.8 2 0 0 2 2 2 0 The GLUG motif AAA_19 PF13245.6 CDJ38707.1 - 0.024 15.0 0.3 0.18 12.1 0.3 2.2 1 1 0 1 1 1 0 AAA domain SUIM_assoc PF16619.5 CDJ38707.1 - 0.042 13.9 6.7 0.096 12.8 6.7 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DEAD PF00270.29 CDJ38707.1 - 0.071 12.9 0.1 0.35 10.6 0.1 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_7 PF12775.7 CDJ38707.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 CDJ38707.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Spt20 PF12090.8 CDJ38707.1 - 0.28 10.7 3.7 0.45 10.1 3.7 1.3 1 0 0 1 1 1 0 Spt20 family AAA_23 PF13476.6 CDJ38707.1 - 0.64 10.5 0.0 0.64 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ38707.1 - 5.4 7.4 7.6 0.26 11.7 0.6 2.4 3 1 0 3 3 3 0 AAA ATPase domain S1 PF00575.23 CDJ38708.1 - 0.14 12.6 0.0 0.55 10.6 0.0 1.9 1 1 0 1 1 1 0 S1 RNA binding domain CBP_BcsF PF11120.8 CDJ38708.1 - 0.25 11.5 1.1 0.69 10.1 0.7 1.9 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsF DUF572 PF04502.13 CDJ38708.1 - 0.81 9.3 9.0 1.2 8.7 9.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Calc_CGRP_IAPP PF00214.19 CDJ38708.1 - 0.93 9.9 4.7 4.3 7.7 4.7 2.1 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Exo_endo_phos PF03372.23 CDJ38710.1 - 2.7e-05 23.8 0.0 6.8e-05 22.5 0.0 1.6 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family SUIM_assoc PF16619.5 CDJ38710.1 - 0.0018 18.3 0.3 0.0094 16.0 0.3 2.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 EF-hand_7 PF13499.6 CDJ38712.1 - 0.011 16.2 0.1 0.021 15.3 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 CDJ38712.1 - 0.011 15.6 0.5 0.045 13.7 0.5 1.9 1 1 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 CDJ38712.1 - 0.05 13.2 0.7 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 EF hand Spt20 PF12090.8 CDJ38712.1 - 0.17 11.4 6.6 0.31 10.6 6.6 1.3 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ38712.1 - 2 8.5 10.3 0.13 12.4 4.8 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Arv1 PF04161.13 CDJ38713.1 - 5.6e-32 111.6 0.5 3.4e-31 109.1 0.4 2.2 2 1 0 2 2 2 1 Arv1-like family PDDEXK_6 PF04720.12 CDJ38713.1 - 0.037 14.0 6.3 0.38 10.7 1.3 2.4 2 0 0 2 2 2 0 PDDEXK-like family of unknown function Nudix_N_2 PF14803.6 CDJ38713.1 - 0.061 13.2 4.4 0.2 11.6 4.4 1.9 1 0 0 1 1 1 0 Nudix N-terminal SR-25 PF10500.9 CDJ38713.1 - 0.089 12.4 0.2 0.089 12.4 0.2 3.4 2 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein PPP4R2 PF09184.11 CDJ38713.1 - 4.8 6.7 10.8 7.3 6.1 10.8 1.4 1 0 0 1 1 1 0 PPP4R2 N-SET PF11764.8 CDJ38714.1 - 3.9 7.5 7.6 6.3 6.9 7.6 1.3 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N SUIM_assoc PF16619.5 CDJ38715.1 - 0.00013 21.9 0.0 0.00013 21.9 0.0 8.4 5 2 1 6 6 6 3 Unstructured region C-term to UIM in Ataxin3 bMG10 PF17973.1 CDJ38716.1 - 0.12 12.5 0.5 0.19 11.9 0.5 1.3 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain TFIIA PF03153.13 CDJ38717.1 - 0.61 10.0 10.4 0.71 9.8 10.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 CDJ38718.1 - 2e-33 113.9 10.0 4e-08 33.8 0.1 9.0 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ38718.1 - 6.3e-05 23.2 0.1 5.2 7.4 0.0 5.0 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ38718.1 - 0.00036 19.6 0.0 0.041 12.8 0.0 2.9 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ38718.1 - 0.031 12.9 0.8 13 4.3 0.1 3.4 4 0 0 4 4 4 0 Nucleoporin Nup120/160 DUF3138 PF11336.8 CDJ38718.1 - 1.5 7.4 7.1 3.3 6.2 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) EMC3_TMCO1 PF01956.16 CDJ38719.1 - 2.9e-07 30.4 0.0 2.4e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like zf-MYND PF01753.18 CDJ38720.1 - 9.2e-13 48.0 11.3 1.6e-12 47.3 11.3 1.4 1 0 0 1 1 1 1 MYND finger Hen1_Lam_C PF18441.1 CDJ38720.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Hen1 La-motif C-terminal domain zf-C6H2 PF15801.5 CDJ38720.1 - 0.063 13.6 10.3 0.15 12.4 10.3 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding EndIII_4Fe-2S PF10576.9 CDJ38720.1 - 7.5 7.0 9.3 0.91 9.9 3.3 2.4 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III DUF4746 PF15928.5 CDJ38721.1 - 4.4 6.7 16.9 0.43 9.9 0.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4746) RskA PF10099.9 CDJ38722.1 - 0.0073 16.6 12.0 0.0073 16.6 12.0 8.2 3 2 2 6 6 6 2 Anti-sigma-K factor rskA Hydrolase_3 PF08282.12 CDJ38723.1 - 9.7e-31 107.4 0.0 8.1e-24 84.7 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ38723.1 - 3e-10 40.0 0.0 1.1e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CDJ38723.1 - 0.00018 21.9 6.3 0.011 16.0 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDJ38723.1 - 0.012 15.7 0.1 0.036 14.1 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Amidohydro_2 PF04909.14 CDJ38723.1 - 0.11 12.3 11.3 0.38 10.5 10.5 2.0 1 1 1 2 2 2 0 Amidohydrolase PCNA_N PF00705.18 CDJ38724.1 - 2.3e-45 153.4 4.8 1.1e-44 151.2 2.4 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CDJ38724.1 - 3.2e-28 98.5 0.0 3.4e-27 95.2 0.0 2.3 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 CDJ38724.1 - 1.6e-07 31.0 1.4 9.6e-05 22.0 0.1 2.1 1 1 1 2 2 2 2 Rad9 zf-MIZ PF02891.20 CDJ38726.1 - 2.6e-17 62.3 2.9 6.6e-17 61.0 2.9 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger DUF2722 PF10846.8 CDJ38726.1 - 0.00015 20.9 2.5 0.00015 20.9 2.5 8.4 4 3 1 6 6 6 1 Protein of unknown function (DUF2722) zf-Nse PF11789.8 CDJ38726.1 - 0.016 15.0 0.9 0.037 13.9 0.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4834 PF16118.5 CDJ38726.1 - 0.041 14.8 0.8 0.041 14.8 0.8 8.2 4 3 0 4 4 4 0 Domain of unknown function (DUF4834) malic PF00390.19 CDJ38726.1 - 0.51 10.1 3.3 0.36 10.6 0.1 2.3 3 0 0 3 3 3 0 Malic enzyme, N-terminal domain Sulfate_transp PF00916.20 CDJ38727.1 - 3.4e-74 249.9 15.6 6.2e-74 249.0 15.6 1.4 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CDJ38727.1 - 1.1e-14 54.1 0.0 2e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain Hint_2 PF13403.6 CDJ38727.1 - 0.19 12.1 0.4 2.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Hint domain DUF4746 PF15928.5 CDJ38729.1 - 2.7 7.3 21.8 0.46 9.8 14.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) AMA-1 PF02430.15 CDJ38730.1 - 2.6e-63 214.6 0.0 3.6e-56 191.1 0.0 2.1 1 1 1 2 2 2 2 Apical membrane antigen 1 S1FA PF04689.13 CDJ38730.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA DUF2371 PF10177.9 CDJ38731.1 - 0.028 14.6 0.0 9.6 6.4 0.0 3.3 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2371) Apt1 PF10351.9 CDJ38731.1 - 0.054 12.4 7.2 5.5 5.7 6.4 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 CDJ38731.1 - 0.26 10.7 2.2 0.67 9.3 0.5 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Amnionless PF14828.6 CDJ38731.1 - 4 6.2 11.5 0.82 8.4 1.7 2.6 3 0 0 3 3 3 0 Amnionless SPT16 PF08644.11 CDJ38732.1 - 2.8e-42 144.4 0.0 2.8e-42 144.4 0.0 3.7 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 CDJ38732.1 - 3.1e-20 72.8 0.2 8e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 FACT-Spt16_Nlob PF14826.6 CDJ38732.1 - 7.8e-16 58.3 0.3 2.1e-14 53.6 0.0 3.0 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.12 CDJ38732.1 - 2.3e-12 47.2 0.0 1e-11 45.1 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like WD40 PF00400.32 CDJ38733.1 - 6.8e-28 96.4 12.2 1.1e-07 32.4 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ38733.1 - 7.8e-12 45.3 0.1 0.017 15.4 0.0 5.4 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 CDJ38733.1 - 8.7e-12 44.5 0.1 2e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 CDJ38733.1 - 4.8e-09 35.6 0.3 0.015 14.3 0.0 3.5 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ38733.1 - 3.1e-05 22.9 0.1 0.075 11.7 0.1 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CDJ38733.1 - 0.01 14.8 0.0 0.051 12.5 0.0 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 CDJ38733.1 - 0.17 11.9 0.0 0.5 10.4 0.0 1.8 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 CDJ38733.1 - 0.18 11.1 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain DUF5531 PF17671.1 CDJ38734.1 - 2.7 7.9 5.6 1.7 8.5 1.3 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5531) TctC PF03401.14 CDJ38735.1 - 0.026 13.6 0.5 0.028 13.5 0.5 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor DUF4106 PF13388.6 CDJ38735.1 - 5.4 6.2 9.6 6.1 6.0 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) S-AdoMet_synt_C PF02773.16 CDJ38737.1 - 5.6e-62 207.8 0.0 1.6e-61 206.3 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CDJ38737.1 - 1.9e-47 160.4 0.0 3.6e-47 159.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CDJ38737.1 - 8.1e-44 148.4 0.2 1.7e-43 147.3 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain FAD-oxidase_C PF02913.19 CDJ38738.1 - 8.1e-43 146.8 0.0 1.5e-42 145.9 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CDJ38738.1 - 2.6e-35 121.2 0.3 4.7e-35 120.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DUF2722 PF10846.8 CDJ38738.1 - 0.024 13.6 1.1 0.035 13.1 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BBE PF08031.12 CDJ38738.1 - 0.098 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like Fungal_trans_2 PF11951.8 CDJ38738.1 - 0.29 9.9 0.7 1.3 7.7 0.0 2.0 2 0 0 2 2 2 0 Fungal specific transcription factor domain Androgen_recep PF02166.16 CDJ38738.1 - 2.5 6.8 13.5 3.6 6.3 13.5 1.2 1 0 0 1 1 1 0 Androgen receptor Tmemb_14 PF03647.13 CDJ38739.1 - 9.4e-08 32.7 9.6 1.5e-07 32.0 9.6 1.3 1 1 0 1 1 1 1 Transmembrane proteins 14C ER_lumen_recept PF00810.18 CDJ38740.1 - 3.2e-31 109.1 3.7 3.2e-31 109.1 3.7 1.8 2 0 0 2 2 2 1 ER lumen protein retaining receptor DUF1422 PF07226.11 CDJ38740.1 - 0.022 14.8 0.1 0.063 13.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) DUF5317 PF17248.2 CDJ38740.1 - 0.19 11.7 14.5 0.12 12.4 1.8 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5317) MASE3 PF17159.4 CDJ38740.1 - 2.8 7.5 12.8 0.35 10.5 0.2 3.0 1 1 1 3 3 3 0 Membrane-associated sensor domain Beta-Casp PF10996.8 CDJ38741.1 - 0.0022 18.3 0.0 0.0089 16.3 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 CDJ38741.1 - 0.07 12.6 0.0 0.61 9.5 0.0 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain SPX PF03105.19 CDJ38741.1 - 0.1 12.5 7.4 0.26 11.2 5.8 2.1 2 0 0 2 2 2 0 SPX domain PI3_PI4_kinase PF00454.27 CDJ38742.1 - 2.7e-22 79.8 0.0 6.1e-20 72.1 0.0 2.9 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase SR-25 PF10500.9 CDJ38744.1 - 0.021 14.4 9.6 0.033 13.8 9.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ELO PF01151.18 CDJ38745.1 - 3.4e-47 161.1 16.7 4.4e-38 131.2 8.8 2.5 3 0 0 3 3 3 2 GNS1/SUR4 family Casein_kappa PF00997.18 CDJ38745.1 - 0.17 11.9 0.9 0.38 10.8 0.9 1.5 1 0 0 1 1 1 0 Kappa casein Miga PF10265.9 CDJ38745.1 - 1.7 7.5 3.8 3.1 6.7 3.8 1.3 1 0 0 1 1 1 0 Mitoguardin SUIM_assoc PF16619.5 CDJ38748.1 - 0.0017 18.4 4.1 0.0017 18.4 4.1 9.0 4 2 2 6 6 6 2 Unstructured region C-term to UIM in Ataxin3 TPR_14 PF13428.6 CDJ38749.1 - 1.4e-08 34.8 25.3 0.0027 18.4 0.0 8.3 4 2 5 9 9 9 3 Tetratricopeptide repeat Suf PF05843.14 CDJ38749.1 - 1.5e-08 35.0 22.6 0.0034 17.4 0.3 5.7 2 1 2 4 4 4 3 Suppressor of forked protein (Suf) HAT PF02184.16 CDJ38749.1 - 7.5e-06 25.8 34.0 6.1 6.9 0.0 10.7 10 1 0 10 10 10 4 HAT (Half-A-TPR) repeat TPR_17 PF13431.6 CDJ38749.1 - 0.0021 18.3 0.7 11 6.7 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ38749.1 - 1.4 9.7 16.8 21 6.0 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CDJ38749.1 - 1.8 8.6 10.0 4.2 7.4 0.6 3.9 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 zf-Tim10_DDP PF02953.15 CDJ38750.1 - 1.8e-11 43.5 0.1 2.7e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_60s PF00428.19 CDJ38750.1 - 0.34 11.5 12.5 0.6 10.7 12.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Rsm22 PF09243.10 CDJ38751.1 - 4.2e-57 193.5 0.2 4.7e-34 117.9 0.4 3.3 3 0 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 Coagulin PF02035.15 CDJ38751.1 - 0.031 14.2 3.7 0.091 12.7 3.8 1.6 2 0 0 2 2 2 0 Coagulin Methyltransf_23 PF13489.6 CDJ38751.1 - 0.032 14.1 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SPX PF03105.19 CDJ38751.1 - 0.079 12.9 9.8 0.72 9.7 0.3 2.4 2 0 0 2 2 2 0 SPX domain Macoilin PF09726.9 CDJ38751.1 - 0.86 8.1 20.8 0.097 11.2 7.4 2.3 2 0 0 2 2 2 0 Macoilin family UCR_14kD PF02271.16 CDJ38752.1 - 1.2e-21 76.6 0.1 1.6e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit UQ_con PF00179.26 CDJ38754.1 - 1.4e-44 151.2 0.0 1.8e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 CDJ38754.1 - 3.2e-07 30.1 0.0 5.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 CDJ38754.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ38754.1 - 0.0088 16.3 0.1 0.019 15.2 0.0 1.6 2 0 0 2 2 2 1 RWD domain UFC1 PF08694.11 CDJ38754.1 - 0.083 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RCC1 PF00415.18 CDJ38755.1 - 3e-32 111.0 13.3 8.1e-09 36.0 0.1 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ38755.1 - 6.6e-18 64.0 16.8 4.6e-06 26.3 0.1 4.7 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat DUF1664 PF07889.12 CDJ38755.1 - 0.0043 17.1 5.5 0.0043 17.1 5.5 7.2 4 1 3 8 8 8 4 Protein of unknown function (DUF1664) LSM PF01423.22 CDJ38756.1 - 5.1e-16 58.1 0.4 6.3e-16 57.8 0.4 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CDJ38756.1 - 0.038 13.6 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Hfq protein SM-ATX PF14438.6 CDJ38756.1 - 0.063 13.4 0.0 0.075 13.2 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain RNA_pol_Rpb1_5 PF04998.17 CDJ38757.1 - 1.3e-100 336.2 0.2 1.9e-100 335.7 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CDJ38757.1 - 9.1e-95 317.6 0.0 1.8e-94 316.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CDJ38757.1 - 1.2e-74 250.0 0.0 2.7e-74 248.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CDJ38757.1 - 4.2e-48 163.7 4.5 7.3e-48 162.9 4.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 CDJ38757.1 - 6.2e-48 162.2 1.6 1.5e-47 160.9 1.6 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 CDJ38757.1 - 7.6e-44 149.4 0.0 2.3e-43 147.9 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CDJ38757.1 - 4.9e-39 132.6 0.2 4.9e-39 132.6 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 CDJ38757.1 - 0.0042 17.4 10.4 0.0042 17.4 10.4 16.2 11 2 2 15 15 15 6 RNA polymerase Rpb1 C-terminal repeat PIG-H PF10181.9 CDJ38758.1 - 2.2e-11 43.4 0.7 4.3e-11 42.5 0.7 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Kelch_4 PF13418.6 CDJ38759.1 - 2.2e-06 27.6 0.2 9.7e-06 25.5 0.1 2.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ38759.1 - 2.5e-05 24.4 0.4 0.0004 20.6 0.0 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 CDJ38759.1 - 0.00017 21.5 0.0 0.0048 16.9 0.0 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 CDJ38759.1 - 0.00027 20.5 0.0 0.00064 19.2 0.0 1.7 1 0 0 1 1 1 1 Kelch motif PAM2 PF07145.15 CDJ38759.1 - 0.011 15.4 0.3 0.022 14.4 0.3 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Kelch_3 PF13415.6 CDJ38759.1 - 0.021 15.1 4.8 0.1 12.9 0.2 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain Mpv17_PMP22 PF04117.12 CDJ38760.1 - 1.6e-11 44.3 0.3 1.6e-11 44.3 0.3 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family PepSY_TM_like_2 PF16357.5 CDJ38760.1 - 0.13 12.2 2.4 1.4 8.9 0.1 2.5 2 0 0 2 2 2 0 Putative PepSY_TM-like Neur_chan_memb PF02932.16 CDJ38760.1 - 0.62 10.1 13.5 0.74 9.8 3.2 2.5 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF4057 PF13266.6 CDJ38762.1 - 0.045 13.4 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) MSL1_dimer PF16801.5 CDJ38762.1 - 1.7 8.5 6.9 4.3 7.2 6.9 1.6 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 zf-CCHC PF00098.23 CDJ38763.1 - 3.2e-05 23.8 0.8 8.7e-05 22.4 0.8 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ38763.1 - 0.00014 21.7 0.6 0.0033 17.4 0.3 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ38763.1 - 0.0065 16.3 0.8 0.017 15.0 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ38763.1 - 0.3 11.0 3.6 0.29 11.0 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-A20 PF01754.16 CDJ38764.1 - 1.3e-11 44.2 7.5 1.3e-11 44.2 7.5 2.4 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 CDJ38764.1 - 1.5e-08 34.7 8.5 1.5e-08 34.7 8.5 2.2 2 0 0 2 2 2 1 AN1-like Zinc finger DUF4428 PF14471.6 CDJ38764.1 - 0.36 10.8 3.6 5.7 6.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) NUP50 PF08911.11 CDJ38765.1 - 0.012 16.2 5.7 0.05 14.3 5.7 2.1 1 1 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) NUDE_C PF04880.13 CDJ38765.1 - 7.3 7.0 16.2 15 6.1 16.0 1.7 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region PRRSV_Env PF02340.15 CDJ38766.1 - 0.0012 18.3 0.0 0.0056 16.1 0.0 2.0 2 0 0 2 2 2 1 PRRSV putative envelope protein TFIID_30kDa PF03540.13 CDJ38768.1 - 3.3e-07 30.2 0.1 5.5e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit zf-UDP PF14569.6 CDJ38768.1 - 0.08 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger Prefoldin PF02996.17 CDJ38769.1 - 4e-17 62.2 1.7 5.3e-17 61.8 1.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit YugN PF08868.10 CDJ38769.1 - 0.081 12.8 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 YugN-like family Cep57_CLD_2 PF14197.6 CDJ38769.1 - 0.18 11.9 2.8 7.6 6.7 0.1 2.6 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Fib_alpha PF08702.10 CDJ38769.1 - 0.29 11.3 2.1 4.6 7.4 0.4 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family zf-CCHC PF00098.23 CDJ38774.1 - 1.2e-06 28.3 18.2 3.2e-06 27.0 3.0 3.1 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ38774.1 - 0.00087 19.2 0.4 0.00087 19.2 0.4 2.6 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ38774.1 - 0.0028 17.5 2.2 0.0028 17.5 2.2 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ38774.1 - 0.022 14.5 6.3 0.035 13.8 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.17 CDJ38774.1 - 0.038 14.3 0.4 0.081 13.2 0.1 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein zf-C4pol PF14260.6 CDJ38774.1 - 0.074 13.5 2.7 0.66 10.5 0.4 2.6 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DnaJ_CXXCXGXG PF00684.19 CDJ38774.1 - 0.077 13.4 7.6 0.16 12.3 7.6 1.5 1 0 0 1 1 1 0 DnaJ central domain zinc-ribbons_6 PF07191.12 CDJ38774.1 - 0.19 11.8 3.0 0.38 10.8 3.0 1.5 1 0 0 1 1 1 0 zinc-ribbons zf-CCHC_5 PF14787.6 CDJ38774.1 - 1.8 8.3 9.3 1.4 8.7 0.9 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 CDJ38774.1 - 2.1 8.3 11.9 0.07 13.0 2.9 2.5 2 0 0 2 2 2 0 Zinc knuckle Chromo PF00385.24 CDJ38776.1 - 7.4e-12 45.0 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain 14-3-3 PF00244.20 CDJ38777.1 - 1.5e-98 328.8 7.3 1.7e-98 328.6 7.3 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_C98 PF15499.6 CDJ38777.1 - 0.033 13.6 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase MKT1_N PF12247.8 CDJ38777.1 - 0.18 12.1 1.4 0.38 11.1 0.1 2.2 2 1 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication EGF_CA PF07645.15 CDJ38778.1 - 2e-24 85.5 82.0 7.9e-11 42.0 9.1 5.7 6 0 0 6 6 6 5 Calcium-binding EGF domain cEGF PF12662.7 CDJ38778.1 - 2.7e-14 52.7 34.0 0.00059 19.7 0.3 6.8 5 1 0 5 5 5 4 Complement Clr-like EGF-like EGF_3 PF12947.7 CDJ38778.1 - 3e-10 40.1 71.3 2.7e-05 24.3 8.8 6.2 6 0 0 6 6 6 4 EGF domain EGF PF00008.27 CDJ38778.1 - 1.8e-05 25.0 59.1 0.016 15.5 5.7 6.5 5 2 0 5 5 5 5 EGF-like domain EGF_MSP1_1 PF12946.7 CDJ38778.1 - 0.0005 20.1 21.5 0.0025 17.8 8.0 4.8 5 0 0 5 5 5 2 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CDJ38778.1 - 0.0025 18.1 66.7 0.045 14.0 4.5 5.9 5 1 0 5 5 5 4 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CDJ38778.1 - 0.0051 17.4 2.2 0.0051 17.4 2.2 7.1 7 0 0 7 7 7 2 Human growth factor-like EGF ORC3_N PF07034.11 CDJ38779.1 - 3.9e-10 39.4 2.1 3.9e-10 39.4 2.1 3.4 3 1 0 3 3 3 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 CDJ38779.1 - 0.00052 20.1 0.0 0.00052 20.1 0.0 3.8 3 2 0 3 3 3 1 Origin recognition complex winged helix C-terminal MRP-S27 PF10037.9 CDJ38780.1 - 0.0048 15.8 18.7 0.0048 15.8 18.7 1.8 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S27 SID-1_RNA_chan PF13965.6 CDJ38780.1 - 0.51 8.7 6.7 0.7 8.2 6.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HSP70 PF00012.20 CDJ38780.1 - 1.3 7.1 21.8 2.4 6.2 21.8 1.3 1 0 0 1 1 1 0 Hsp70 protein LMBR1 PF04791.16 CDJ38780.1 - 1.5 7.7 11.3 2 7.2 11.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 CDJ38780.1 - 2.1 6.8 16.7 3.6 6.1 16.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Pkinase PF00069.25 CDJ38781.1 - 9.7e-61 205.4 0.0 1.5e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ38781.1 - 1.1e-37 129.7 0.2 1.6e-37 129.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ38781.1 - 2.4e-15 56.6 0.0 7.3e-15 55.0 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ38781.1 - 4.5e-06 26.2 0.0 7.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ38781.1 - 1e-05 25.6 0.1 1e-05 25.6 0.1 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ38781.1 - 0.00065 18.6 0.4 0.012 14.4 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 CDJ38781.1 - 0.0059 15.6 0.0 0.0094 14.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CDJ38781.1 - 0.022 14.3 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase TFIIA PF03153.13 CDJ38781.1 - 0.026 14.5 19.6 0.033 14.2 19.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit KAR9 PF08580.10 CDJ38781.1 - 1.3 7.5 13.2 1.6 7.1 13.2 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Hamartin PF04388.12 CDJ38781.1 - 5.3 5.6 18.1 6.9 5.2 18.1 1.1 1 0 0 1 1 1 0 Hamartin protein CCSAP PF15748.5 CDJ38781.1 - 7.6 6.6 17.7 11 6.1 17.7 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PAN_1 PF00024.26 CDJ38783.1 - 0.017 15.0 0.9 0.017 15.0 0.9 2.2 2 0 0 2 2 2 0 PAN domain PAN_4 PF14295.6 CDJ38783.1 - 0.019 14.8 0.6 0.061 13.2 0.6 1.8 1 0 0 1 1 1 0 PAN domain Phage_holin_3_3 PF16083.5 CDJ38783.1 - 0.85 9.8 4.3 1.3 9.1 3.1 2.0 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III Herpes_U47 PF05467.11 CDJ38783.1 - 7.4 4.6 8.2 4.6 5.3 4.7 2.0 2 0 0 2 2 2 0 Herpesvirus glycoprotein U47 SAE2 PF08573.10 CDJ38784.1 - 5.4e-06 27.5 6.6 5.4e-06 27.5 6.6 5.1 4 1 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus AAA_11 PF13086.6 CDJ38784.1 - 0.25 11.1 18.8 0.41 10.4 0.9 2.4 2 0 0 2 2 2 0 AAA domain MtN3_slv PF03083.16 CDJ38786.1 - 6.2e-34 115.9 3.4 6.8e-19 67.7 0.2 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange LAB_N PF07578.11 CDJ38786.1 - 0.00085 19.4 0.2 0.92 9.6 0.0 2.7 2 0 0 2 2 2 2 Lipid A Biosynthesis N-terminal domain AP2 PF00847.20 CDJ38787.1 - 9.4e-12 45.0 0.5 4.3e-11 42.9 0.5 2.2 1 0 0 1 1 1 1 AP2 domain zf-HC5HC2H_2 PF13832.6 CDJ38788.1 - 1.3e-20 73.6 38.2 1.1e-12 48.1 1.6 6.1 6 0 0 6 6 6 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDJ38788.1 - 2.5e-14 53.3 15.9 1.1e-08 35.1 4.6 5.8 6 0 0 6 6 6 3 PHD-like zinc-binding domain PHD_2 PF13831.6 CDJ38788.1 - 4.4e-06 26.2 2.1 4.4e-06 26.2 2.1 3.5 3 0 0 3 3 3 1 PHD-finger RIX1 PF08167.12 CDJ38788.1 - 0.0036 17.1 2.5 0.01 15.6 2.5 1.7 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis TUDOR_5 PF18359.1 CDJ38788.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 DUF5428 PF17493.2 CDJ38789.1 - 0.28 11.6 2.2 21 5.6 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5428) DEAD PF00270.29 CDJ38791.1 - 2.8e-36 124.9 0.0 4.3e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase NUC153 PF08159.12 CDJ38792.1 - 0.001 18.8 0.2 0.0024 17.7 0.2 1.7 1 0 0 1 1 1 1 NUC153 domain RskA PF10099.9 CDJ38792.1 - 0.0093 16.3 2.2 0.0093 16.3 2.2 5.6 3 2 3 6 6 6 1 Anti-sigma-K factor rskA ANAPC4_WD40 PF12894.7 CDJ38792.1 - 0.055 13.8 0.0 0.19 12.0 0.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF755 PF05501.11 CDJ38793.1 - 0.0027 18.0 20.4 0.0027 18.0 20.4 2.4 2 0 0 2 2 1 1 Domain of unknown function (DUF755) Spt20 PF12090.8 CDJ38793.1 - 0.073 12.7 21.4 0.19 11.3 21.4 1.6 1 0 0 1 1 1 0 Spt20 family PA26 PF04636.13 CDJ38793.1 - 0.27 10.1 5.6 0.058 12.3 1.8 1.7 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) GREB1 PF15782.5 CDJ38793.1 - 0.27 8.3 14.0 0.0044 14.2 6.8 1.5 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer RdRP_2 PF00978.21 CDJ38793.1 - 0.4 9.5 3.5 0.66 8.8 3.5 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase GvpK PF05121.12 CDJ38793.1 - 0.51 10.4 7.5 1.6 8.8 7.5 1.8 1 0 0 1 1 1 0 Gas vesicle protein K Activator_LAG-3 PF11498.8 CDJ38793.1 - 1.4 7.8 25.6 2.8 6.8 25.6 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF1635 PF07795.11 CDJ38793.1 - 1.5 8.6 17.5 0.045 13.6 9.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) PEX11 PF05648.14 CDJ38793.1 - 1.5 8.2 6.5 3.1 7.2 6.5 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) SPT16 PF08644.11 CDJ38793.1 - 3.5 7.8 6.7 7.3 6.8 6.7 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) RICTOR_N PF14664.6 CDJ38793.1 - 3.8 6.4 6.8 2.3 7.1 0.1 2.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term V_ATPase_I PF01496.19 CDJ38793.1 - 4.8 5.0 6.2 7.9 4.3 6.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4834 PF16118.5 CDJ38793.1 - 5.7 8.0 11.7 1.4 9.9 6.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) MPM1 PF17234.2 CDJ38793.1 - 6.7 6.9 11.1 15 5.8 11.1 1.5 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 TMEM51 PF15345.6 CDJ38793.1 - 7.9 6.2 16.4 0.11 12.3 7.9 2.3 2 0 0 2 2 1 0 Transmembrane protein 51 SR-25 PF10500.9 CDJ38794.1 - 0.0017 18.0 11.7 0.0018 17.9 11.7 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDK2AP PF09806.9 CDJ38794.1 - 2.3 8.2 11.6 2.6 8.1 11.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1635 PF07795.11 CDJ38794.1 - 3.7 7.4 17.4 5.8 6.7 17.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) CCSAP PF15748.5 CDJ38795.1 - 0.014 15.6 13.7 1.2 9.3 0.2 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated SUIM_assoc PF16619.5 CDJ38795.1 - 8.2 6.6 16.1 0.039 14.0 5.6 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 IspD PF01128.19 CDJ38796.1 - 1.2e-07 31.7 5.9 0.00027 20.7 2.9 3.1 3 0 0 3 3 3 2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase TAS2R PF05296.13 CDJ38796.1 - 0.55 9.3 1.0 0.84 8.7 1.0 1.2 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) Sin_N PF04801.13 CDJ38796.1 - 3.5 6.7 31.5 0.15 11.2 23.8 2.1 2 0 0 2 2 2 0 Sin-like protein conserved region Baculo_PP31 PF05311.11 CDJ38796.1 - 7.8 5.9 12.6 1.4 8.4 7.8 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) TFIIA PF03153.13 CDJ38798.1 - 0.021 14.9 4.5 0.023 14.7 4.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Metallophos PF00149.28 CDJ38799.1 - 9.9e-21 75.2 0.0 1.3e-20 74.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nop53 PF07767.11 CDJ38801.1 - 1.8 7.9 7.5 2.1 7.6 7.5 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF3391 PF11871.8 CDJ38801.1 - 2.8 8.5 9.9 3.3 8.3 9.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Spt20 PF12090.8 CDJ38802.1 - 0.0043 16.7 2.0 0.0043 16.7 2.0 2.7 3 0 0 3 3 3 1 Spt20 family CopD PF05425.13 CDJ38802.1 - 0.12 12.8 0.2 0.12 12.8 0.2 2.0 2 0 0 2 2 2 0 Copper resistance protein D DUF4667 PF15700.5 CDJ38802.1 - 3.9 7.5 38.8 0.76 9.8 6.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) AIF_C PF14721.6 CDJ38803.1 - 0.0025 18.2 4.1 0.0072 16.7 0.3 2.1 2 0 0 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Presenilin PF01080.17 CDJ38803.1 - 0.017 13.9 10.9 0.025 13.4 10.9 1.2 1 0 0 1 1 1 0 Presenilin Eapp_C PF10238.9 CDJ38803.1 - 0.017 15.2 8.9 0.12 12.5 2.8 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF4199 PF13858.6 CDJ38803.1 - 0.026 14.9 1.7 0.026 14.9 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) FAM176 PF14851.6 CDJ38803.1 - 0.075 12.7 4.2 0.14 11.8 1.4 2.1 2 0 0 2 2 2 0 FAM176 family Orf78 PF06024.12 CDJ38803.1 - 0.14 12.5 3.1 0.6 10.4 0.2 2.2 2 0 0 2 2 2 0 Orf78 (ac78) DUF2417 PF10329.9 CDJ38803.1 - 0.35 10.2 1.0 1.1 8.6 0.0 1.9 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Peroxin-13_N PF04088.13 CDJ38803.1 - 0.35 11.1 4.8 0.27 11.5 0.7 2.0 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF5385 PF17359.2 CDJ38803.1 - 0.36 10.4 13.3 0.14 11.7 3.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5385) DUF3464 PF11947.8 CDJ38803.1 - 0.39 10.5 12.7 0.21 11.3 3.1 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 TRAP_alpha PF03896.16 CDJ38803.1 - 0.43 9.7 5.8 0.075 12.2 2.1 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit RPA43_OB PF17875.1 CDJ38803.1 - 0.94 10.1 6.5 2 9.1 2.8 2.1 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I F-protein PF00469.20 CDJ38803.1 - 1.1 8.9 13.1 4.2 6.9 0.4 2.1 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef CPSF100_C PF13299.6 CDJ38803.1 - 1.2 9.3 14.0 1.3 9.2 7.8 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TERB2 PF15101.6 CDJ38803.1 - 1.3 9.1 19.6 2 8.4 10.7 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 CAF1 PF04857.20 CDJ38803.1 - 1.4 8.0 7.1 1.9 7.6 7.1 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease TFB6 PF17110.5 CDJ38803.1 - 1.6 8.5 6.7 4.7 6.9 4.5 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH CTU2 PF10288.9 CDJ38803.1 - 1.8 8.9 11.8 3.1 8.1 5.1 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 EIIBC-GUT_N PF03612.14 CDJ38803.1 - 1.8 8.3 11.9 1.7 8.3 5.9 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Afi1 PF07792.12 CDJ38803.1 - 2.1 8.8 13.7 1.5 9.3 5.5 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking OATP PF03137.20 CDJ38803.1 - 2.5 6.3 6.5 0.44 8.8 0.9 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4834 PF16118.5 CDJ38803.1 - 2.8 9.0 17.0 1.7 9.6 7.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3408 PF11888.8 CDJ38803.1 - 3 8.0 17.1 1.8 8.7 9.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Usp PF00582.26 CDJ38803.1 - 3.4 8.2 11.8 7.8 7.0 0.6 2.2 2 0 0 2 2 2 0 Universal stress protein family DUF2722 PF10846.8 CDJ38803.1 - 3.4 6.5 34.5 0.19 10.6 14.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) FYDLN_acid PF09538.10 CDJ38803.1 - 5.6 7.7 12.3 2.5 8.8 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Ndc1_Nup PF09531.10 CDJ38803.1 - 8.1 5.0 15.7 11 4.6 15.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PRC2_HTH_1 PF18118.1 CDJ38803.1 - 8.7 7.2 11.3 10 7.0 5.9 2.1 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain RMP PF14996.6 CDJ38803.1 - 10 6.4 12.3 11 6.2 4.6 2.1 2 0 0 2 2 2 0 Retinal Maintenance UPF0160 PF03690.13 CDJ38804.1 - 1.4e-19 70.9 0.0 1.5e-15 57.6 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0160) zf-C2HC5 PF06221.13 CDJ38805.1 - 0.015 15.3 6.2 0.09 12.8 6.2 2.4 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type CCDC-167 PF15188.6 CDJ38805.1 - 0.1 12.9 6.2 0.43 10.9 6.2 2.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Alkyl_sulf_dimr PF14863.6 CDJ38806.1 - 1.9e-20 73.7 0.0 5.1e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 CDJ38806.1 - 1.7e-18 67.3 0.3 2.9e-17 63.4 0.0 2.8 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDJ38806.1 - 0.00012 21.6 2.1 0.00041 19.9 0.1 2.6 2 1 1 3 3 3 1 Beta-lactamase superfamily domain ESM4 PF15952.5 CDJ38806.1 - 0.0027 18.2 7.2 0.0027 18.2 7.2 2.0 2 0 0 2 2 2 1 Enhancer of split M4 family Rtf2 PF04641.12 CDJ38806.1 - 0.0031 16.9 3.0 0.0047 16.3 3.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger DUF5308 PF17233.2 CDJ38806.1 - 0.024 14.9 3.3 0.032 14.5 1.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5308) SpoIIP PF07454.11 CDJ38806.1 - 0.034 13.6 3.6 0.056 12.9 3.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SARAF PF06682.12 CDJ38806.1 - 0.15 11.6 6.3 0.22 11.1 5.4 1.7 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis CLN3 PF02487.17 CDJ38806.1 - 0.31 10.0 2.0 0.98 8.4 0.6 2.0 2 0 0 2 2 2 0 CLN3 protein Prok-JAB PF14464.6 CDJ38806.1 - 0.34 10.7 3.2 1.3 8.8 2.2 2.4 2 2 0 2 2 2 0 Prokaryotic homologs of the JAB domain PNISR PF15996.5 CDJ38806.1 - 0.42 10.9 12.0 0.088 13.1 8.2 1.7 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR MDM10 PF12519.8 CDJ38806.1 - 1.1 8.0 3.0 1.4 7.7 3.0 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Sec62 PF03839.16 CDJ38806.1 - 1.2 8.6 4.8 2.6 7.5 4.8 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Borrelia_P83 PF05262.11 CDJ38806.1 - 1.7 7.1 6.4 2.5 6.5 6.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 CDJ38806.1 - 2.6 6.7 8.7 4.2 6.0 8.7 1.2 1 0 0 1 1 1 0 Presenilin RskA PF10099.9 CDJ38806.1 - 2.9 8.1 20.5 0.62 10.3 0.7 3.4 2 1 1 3 3 3 0 Anti-sigma-K factor rskA TERB2 PF15101.6 CDJ38806.1 - 4.4 7.3 9.8 4.1 7.4 7.8 1.8 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Spt20 PF12090.8 CDJ38806.1 - 4.4 6.8 31.3 9.1 5.8 0.5 2.2 2 0 0 2 2 2 0 Spt20 family RR_TM4-6 PF06459.12 CDJ38806.1 - 5.9 6.6 8.6 10 5.9 8.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4456 PF14644.6 CDJ38806.1 - 9.6 5.8 21.0 0.13 11.9 13.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) HSP70 PF00012.20 CDJ38807.1 - 0.014 13.6 0.1 0.014 13.6 0.1 1.0 1 0 0 1 1 1 0 Hsp70 protein SUIM_assoc PF16619.5 CDJ38808.1 - 6.4 6.9 27.5 0.36 10.9 9.2 2.9 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Fmp27_WPPW PF10359.9 CDJ38809.1 - 0.44 9.4 12.0 0.13 11.1 8.2 1.9 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Sec7 PF01369.20 CDJ38812.1 - 1.1e-37 129.5 0.0 2.8e-37 128.2 0.0 1.6 2 0 0 2 2 2 1 Sec7 domain RabGAP-TBC PF00566.18 CDJ38812.1 - 7.9e-28 97.6 0.9 3.8e-27 95.4 0.2 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PAN_1 PF00024.26 CDJ38813.1 - 7.1e-05 22.7 0.6 0.00015 21.7 0.6 1.5 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 CDJ38813.1 - 0.00018 21.3 0.6 0.00038 20.2 0.6 1.5 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.6 CDJ38813.1 - 0.00048 20.0 6.1 0.00048 20.0 6.1 2.3 3 1 0 3 3 3 1 PAN domain Collagen PF01391.18 CDJ38813.1 - 0.44 10.3 24.1 0.071 12.9 18.8 2.3 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) DUF3458_C PF17432.2 CDJ38814.1 - 1.1e-62 212.2 7.1 1.3e-62 212.1 7.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats HD_assoc PF13286.6 CDJ38814.1 - 0.12 12.9 0.8 14 6.3 0.0 3.2 2 1 0 3 3 3 0 Phosphohydrolase-associated domain DUF1995 PF09353.10 CDJ38814.1 - 0.26 11.3 2.3 0.33 11.0 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) DUF4813 PF16072.5 CDJ38815.1 - 7.7 6.1 31.7 11 5.6 31.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF2722 PF10846.8 CDJ38816.1 - 0.028 13.4 11.5 0.045 12.7 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF3464 PF11947.8 CDJ38816.1 - 0.22 11.2 3.8 0.37 10.5 3.8 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Presenilin PF01080.17 CDJ38816.1 - 0.35 9.6 8.2 0.6 8.8 8.2 1.3 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CDJ38816.1 - 0.39 8.6 4.0 0.51 8.2 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SprA-related PF12118.8 CDJ38816.1 - 1 8.4 19.6 2.5 7.1 19.7 1.5 2 0 0 2 2 2 0 SprA-related family Suf PF05843.14 CDJ38816.1 - 1.1 9.2 10.5 1.4 8.8 10.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ38816.1 - 2.4 8.2 6.1 3.2 7.7 6.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ38816.1 - 4.4 7.2 30.6 6.5 6.6 30.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_16 PF13191.6 CDJ38817.1 - 1.5e-05 25.5 0.2 2.4e-05 24.8 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CDJ38817.1 - 0.00017 21.8 0.1 0.00039 20.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ38817.1 - 0.00028 21.2 0.0 0.00039 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CDJ38817.1 - 0.00081 18.9 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_25 PF13481.6 CDJ38817.1 - 0.00096 18.8 0.5 0.0018 17.9 0.5 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDJ38817.1 - 0.0035 17.9 0.0 0.0057 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CDJ38817.1 - 0.006 16.6 0.0 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ38817.1 - 0.006 17.0 0.0 0.0092 16.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CDJ38817.1 - 0.011 15.5 0.4 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 CDJ38817.1 - 0.012 15.5 0.0 0.032 14.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 CDJ38817.1 - 0.041 13.2 0.1 0.063 12.6 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 CDJ38817.1 - 0.046 14.0 0.3 0.086 13.1 0.3 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CDJ38817.1 - 0.049 13.3 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CDJ38817.1 - 0.05 13.0 1.1 0.057 12.8 0.1 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDJ38817.1 - 0.14 12.5 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AF-4 PF05110.13 CDJ38817.1 - 0.15 10.1 8.8 0.19 9.8 8.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein 6PGD PF00393.19 CDJ38818.1 - 1.6e-54 185.2 0.0 2.1e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CDJ38818.1 - 1.2e-08 35.3 0.3 1.9e-08 34.7 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Exo84_C PF16528.5 CDJ38818.1 - 0.17 11.6 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Exocyst component 84 C-terminal Isy1 PF06246.12 CDJ38821.1 - 0.059 12.9 9.7 0.14 11.7 2.9 2.4 2 0 0 2 2 2 0 Isy1-like splicing family RR_TM4-6 PF06459.12 CDJ38821.1 - 0.5 10.2 13.7 1.4 8.7 0.7 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ38821.1 - 4.1 7.4 12.0 1.4 9.0 2.0 3.2 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 CDJ38821.1 - 5.3 6.7 8.3 5.1 6.8 3.2 2.4 2 0 0 2 2 2 0 Connexin SNF2_N PF00176.23 CDJ38822.1 - 1.5e-60 204.8 0.0 1.5e-60 204.8 0.0 2.9 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ38822.1 - 4.3e-14 52.8 0.5 3.4e-10 40.2 0.0 3.2 1 1 1 2 2 2 2 Helicase conserved C-terminal domain HSP90 PF00183.18 CDJ38823.1 - 8e-07 28.3 0.0 1.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 CDJ38823.1 - 0.003 17.4 0.0 0.092 12.6 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Spt20 PF12090.8 CDJ38823.1 - 0.021 14.4 0.4 0.021 14.4 0.4 1.7 2 0 0 2 2 2 0 Spt20 family Spc24 PF08286.11 CDJ38823.1 - 0.068 13.4 1.3 2.6 8.3 0.1 3.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF755 PF05501.11 CDJ38823.1 - 0.24 11.7 14.3 0.18 12.1 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF3446 PF11928.8 CDJ38823.1 - 1.3 9.4 11.9 0.47 10.8 0.5 2.7 3 0 0 3 3 3 0 Early growth response N-terminal domain Ribosomal_60s PF00428.19 CDJ38823.1 - 3.4 8.3 22.5 0.26 11.9 13.7 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein SUIM_assoc PF16619.5 CDJ38824.1 - 1.2 9.3 16.2 0.25 11.4 8.6 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Dehydrin PF00257.19 CDJ38824.1 - 1.4 9.4 5.8 13 6.3 0.5 2.6 3 0 0 3 3 3 0 Dehydrin VCBS PF13517.6 CDJ38825.1 - 2.6e-06 27.9 0.0 0.01 16.4 0.0 2.9 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CDJ38825.1 - 0.00015 21.8 0.0 0.12 12.5 0.1 2.5 2 0 0 2 2 2 2 FG-GAP repeat DUF3446 PF11928.8 CDJ38825.1 - 0.0096 16.2 2.6 1.5 9.2 1.0 2.3 2 0 0 2 2 2 2 Early growth response N-terminal domain LIM_bind PF01803.16 CDJ38825.1 - 0.049 13.2 0.3 0.058 12.9 0.3 1.1 1 0 0 1 1 1 0 LIM-domain binding protein SUIM_assoc PF16619.5 CDJ38825.1 - 0.095 12.8 8.8 0.18 11.9 8.8 1.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Roughex PF06020.11 CDJ38825.1 - 2.8 7.0 5.3 3.8 6.5 5.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Methyltransf_16 PF10294.9 CDJ38826.1 - 1.2e-05 25.1 0.1 0.026 14.3 0.3 3.2 2 1 0 2 2 2 2 Lysine methyltransferase UbiA PF01040.18 CDJ38827.1 - 7.6e-08 32.0 0.0 7.6e-08 32.0 0.0 3.7 3 1 0 4 4 4 1 UbiA prenyltransferase family SR-25 PF10500.9 CDJ38828.1 - 0.00085 19.0 2.9 0.00085 19.0 2.9 3.4 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ38828.1 - 0.028 14.0 23.7 0.46 10.1 13.0 2.3 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ38828.1 - 0.49 9.3 22.1 0.34 9.8 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF3337 PF11816.8 CDJ38828.1 - 0.79 9.6 3.8 2.1 8.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3337) Isy1 PF06246.12 CDJ38828.1 - 0.92 9.0 6.0 6 6.3 6.0 2.0 1 1 0 1 1 1 0 Isy1-like splicing family BRF1 PF07741.13 CDJ38828.1 - 3.4 8.0 5.1 18 5.7 0.1 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain SPX PF03105.19 CDJ38828.1 - 4.4 7.1 15.9 3.5 7.4 6.3 2.1 2 0 0 2 2 2 0 SPX domain SOBP PF15279.6 CDJ38828.1 - 7.2 7.1 30.9 4.3 7.9 6.4 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein Peptidase_C54 PF03416.19 CDJ38830.1 - 4.9e-09 36.0 0.4 7.7e-09 35.4 0.4 1.2 1 0 0 1 1 1 1 Peptidase family C54 PhoR PF11808.8 CDJ38830.1 - 0.44 11.0 2.7 2.4 8.6 0.2 2.6 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR TFIIA PF03153.13 CDJ38832.1 - 0.039 14.0 10.2 0.033 14.2 10.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ38832.1 - 0.47 11.5 3.3 0.53 11.3 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ38832.1 - 8.3 5.9 23.2 9.2 5.8 23.2 1.1 1 0 0 1 1 1 0 Spt20 family Hexapep PF00132.24 CDJ38835.1 - 0.00041 20.0 0.2 0.0006 19.4 0.2 1.3 1 0 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) MORN PF02493.20 CDJ38838.1 - 4.9e-21 73.3 14.6 5.8e-07 29.0 0.4 3.3 3 0 0 3 3 3 3 MORN repeat PMR5N PF14416.6 CDJ38838.1 - 2.7 8.4 4.8 22 5.4 0.1 2.9 3 0 0 3 3 3 0 PMR5 N terminal Domain Sec1 PF00995.23 CDJ38840.1 - 1.8e-12 47.3 0.0 2.2e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family UQ_con PF00179.26 CDJ38847.1 - 9.3e-24 83.7 6.6 2.3e-23 82.4 6.6 1.8 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme DDHD PF02862.17 CDJ38847.1 - 6.8e-05 23.1 1.2 7e-05 23.1 1.2 1.2 1 0 0 1 1 1 1 DDHD domain UEV PF05743.13 CDJ38847.1 - 0.00078 19.3 0.8 0.0013 18.5 0.8 1.4 1 0 0 1 1 1 1 UEV domain Pex14_N PF04695.13 CDJ38847.1 - 0.0011 19.7 18.1 0.0015 19.2 18.1 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ38847.1 - 0.0018 18.4 15.2 0.0024 17.9 15.2 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) EPL1 PF10513.9 CDJ38847.1 - 0.028 14.8 10.3 0.039 14.3 10.3 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like RP-C_C PF11800.8 CDJ38847.1 - 0.032 14.3 9.8 0.04 14.0 9.8 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Presenilin PF01080.17 CDJ38847.1 - 0.057 12.2 15.2 0.067 11.9 15.2 1.1 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 CDJ38847.1 - 0.061 12.1 9.2 0.082 11.7 9.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GPCR_chapero_1 PF11904.8 CDJ38847.1 - 0.063 12.7 9.5 0.055 12.9 6.4 2.0 2 0 0 2 2 2 0 GPCR-chaperone Otopetrin PF03189.13 CDJ38847.1 - 0.1 11.4 2.2 0.11 11.3 2.2 1.1 1 0 0 1 1 1 0 Otopetrin RXT2_N PF08595.11 CDJ38847.1 - 0.2 11.7 12.4 0.31 11.1 12.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal SpoIIP PF07454.11 CDJ38847.1 - 0.21 11.0 12.6 0.26 10.7 12.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) V_ATPase_I PF01496.19 CDJ38847.1 - 0.21 9.5 13.2 0.25 9.2 13.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4569 PF15133.6 CDJ38847.1 - 0.22 11.2 15.5 0.3 10.8 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Ndc1_Nup PF09531.10 CDJ38847.1 - 0.23 10.1 8.3 0.26 9.9 8.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Folate_carrier PF01770.18 CDJ38847.1 - 0.3 9.8 3.7 0.37 9.5 3.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier Lys-AminoMut_A PF09043.11 CDJ38847.1 - 0.37 9.2 2.9 0.46 8.9 2.9 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit RR_TM4-6 PF06459.12 CDJ38847.1 - 0.43 10.4 13.8 0.55 10.0 13.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCDC53 PF10152.9 CDJ38847.1 - 0.5 10.8 13.4 0.75 10.2 13.4 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SLC12 PF03522.15 CDJ38847.1 - 0.58 9.1 14.3 0.72 8.8 14.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CPSF100_C PF13299.6 CDJ38847.1 - 0.59 10.3 10.0 0.84 9.8 10.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CLN3 PF02487.17 CDJ38847.1 - 0.67 8.9 11.3 0.89 8.5 11.3 1.1 1 0 0 1 1 1 0 CLN3 protein CDC45 PF02724.14 CDJ38847.1 - 0.71 8.1 13.0 0.91 7.7 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 CDJ38847.1 - 0.74 9.5 11.6 1.2 8.9 11.6 1.3 1 0 0 1 1 1 0 Connexin Band_3_cyto PF07565.13 CDJ38847.1 - 0.75 9.6 13.2 1 9.1 13.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Glyco_hydro_35 PF01301.19 CDJ38847.1 - 0.79 9.3 7.2 1 8.9 7.2 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 FAM60A PF15396.6 CDJ38847.1 - 0.88 9.5 13.0 1.2 9.1 13.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 CDJ38847.1 - 0.97 7.5 12.8 1.3 7.1 12.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MAP7 PF05672.11 CDJ38847.1 - 1 9.1 36.4 1.4 8.6 36.4 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family eIF-3_zeta PF05091.12 CDJ38847.1 - 1.1 8.1 20.1 1.4 7.8 20.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ38847.1 - 1.2 9.2 12.8 1.5 8.9 12.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2828 PF11443.8 CDJ38847.1 - 1.3 7.0 14.9 1.7 6.7 14.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) OATP PF03137.20 CDJ38847.1 - 1.4 7.1 4.7 1.8 6.8 4.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ALMT PF11744.8 CDJ38847.1 - 1.6 7.5 11.2 1.9 7.2 11.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Rtf2 PF04641.12 CDJ38847.1 - 1.8 7.8 12.2 2.5 7.4 12.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Gti1_Pac2 PF09729.9 CDJ38847.1 - 2.3 8.3 11.5 3.3 7.8 11.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Endostatin PF06482.11 CDJ38847.1 - 2.4 7.6 15.1 2.8 7.3 15.1 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF2370 PF10176.9 CDJ38847.1 - 3.2 7.3 6.7 4.6 6.8 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) PAT1 PF09770.9 CDJ38847.1 - 3.5 5.8 28.4 4.1 5.6 28.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM176 PF14851.6 CDJ38847.1 - 3.6 7.2 10.3 5.4 6.7 10.3 1.3 1 0 0 1 1 1 0 FAM176 family CSG2 PF16965.5 CDJ38847.1 - 4.1 6.3 6.7 6.2 5.6 6.7 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4746 PF15928.5 CDJ38847.1 - 4.6 6.6 12.9 6.5 6.1 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIA PF03153.13 CDJ38847.1 - 4.8 7.1 41.7 6.3 6.7 41.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PepSY_TM PF03929.16 CDJ38847.1 - 5.4 6.6 8.8 8.1 6.0 8.8 1.3 1 0 0 1 1 1 0 PepSY-associated TM region EOS1 PF12326.8 CDJ38847.1 - 6.6 6.6 6.4 12 5.8 6.4 1.5 1 0 0 1 1 1 0 N-glycosylation protein Zip PF02535.22 CDJ38847.1 - 7.1 5.7 9.4 9.4 5.3 9.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MMU163 PF17119.5 CDJ38847.1 - 8.3 5.5 9.6 12 5.0 9.6 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis NPR3 PF03666.13 CDJ38847.1 - 8.7 5.0 19.9 0.32 9.7 11.9 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1980 PF09323.10 CDJ38847.1 - 9.9 6.0 8.7 16 5.4 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SUIM_assoc PF16619.5 CDJ38849.1 - 0.00052 20.0 37.6 0.35 11.0 0.1 4.8 4 0 0 4 4 4 4 Unstructured region C-term to UIM in Ataxin3 DUF4179 PF13786.6 CDJ38849.1 - 0.013 16.0 0.5 7.8 7.0 0.9 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) Med15 PF09606.10 CDJ38849.1 - 0.24 10.0 50.3 0.62 8.7 32.7 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal UQ_con PF00179.26 CDJ38850.1 - 1.2e-36 125.4 0.0 1.4e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Topoisom_I_N PF02919.15 CDJ38851.1 - 8.5e-25 87.5 0.1 1.5e-24 86.7 0.0 1.4 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF2057 PF09829.9 CDJ38851.1 - 2.6 8.2 5.7 3.6 7.7 5.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF3123 PF11321.8 CDJ38851.1 - 5.1 7.8 8.9 8.1 7.2 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Bromodomain PF00439.25 CDJ38853.1 - 4.2e-14 52.4 0.0 8.1e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain SUIM_assoc PF16619.5 CDJ38853.1 - 0.052 13.6 13.9 0.031 14.3 2.4 3.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HD_assoc PF13286.6 CDJ38854.1 - 1.6 9.3 4.8 0.51 10.9 0.6 2.3 3 0 0 3 3 3 0 Phosphohydrolase-associated domain PAT1 PF09770.9 CDJ38854.1 - 4.5 5.4 25.0 5.3 5.2 25.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 tRNA-synt_His PF13393.6 CDJ38854.1 - 9.6 5.4 12.8 0.2 10.9 1.1 2.4 2 1 1 3 3 3 0 Histidyl-tRNA synthetase Thioredoxin_6 PF13848.6 CDJ38856.1 - 8.7e-11 42.1 0.0 1.5e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 CDJ38856.1 - 4.4e-07 29.8 0.0 1.3e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Tic110 PF16940.5 CDJ38856.1 - 0.91 7.9 7.6 1.1 7.6 7.6 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Adeno_PV PF03910.13 CDJ38856.1 - 1.5 7.5 3.4 2 7.0 3.4 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV FAIM1 PF06905.13 CDJ38859.1 - 0.002 17.8 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) TFIIA PF03153.13 CDJ38859.1 - 0.039 13.9 20.5 0.014 15.4 11.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ38859.1 - 4.1 7.6 23.5 58 3.8 6.4 3.8 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Phostensin_N PF13916.6 CDJ38860.1 - 0.02 15.3 1.5 0.58 10.5 1.5 2.3 1 1 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal PAP2 PF01569.21 CDJ38861.1 - 0.036 13.8 0.3 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 PAP2 superfamily Utp14 PF04615.13 CDJ38861.1 - 0.99 7.9 34.7 1.7 7.1 34.7 1.3 1 0 0 1 1 1 0 Utp14 protein SR-25 PF10500.9 CDJ38862.1 - 0.06 13.0 5.9 0.062 12.9 5.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ38863.1 - 0.018 15.1 3.1 0.024 14.7 3.1 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Choline_kinase PF01633.20 CDJ38864.1 - 4.2e-14 52.7 0.0 1.4e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Sin_N PF04801.13 CDJ38864.1 - 0.012 14.9 6.5 0.015 14.5 6.5 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region FAM60A PF15396.6 CDJ38864.1 - 0.051 13.6 2.8 0.1 12.6 2.8 1.4 1 1 0 1 1 1 0 Protein Family FAM60A FIST PF08495.10 CDJ38864.1 - 0.082 12.9 0.0 0.15 12.0 0.0 1.5 2 0 0 2 2 2 0 FIST N domain Med15 PF09606.10 CDJ38864.1 - 0.97 8.0 18.5 1.2 7.8 18.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ38864.1 - 1.6 8.6 17.3 2.2 8.2 17.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PepSY_2 PF13670.6 CDJ38864.1 - 7.6 6.6 10.1 0.26 11.3 0.9 2.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF3138 PF11336.8 CDJ38864.1 - 7.6 5.0 8.5 11 4.5 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2722 PF10846.8 CDJ38865.1 - 0.00024 20.2 6.1 0.00024 20.2 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) ArAE_2_N PF10337.9 CDJ38865.1 - 0.0045 16.1 1.2 0.0056 15.8 1.2 1.1 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal FAD_SOX PF18371.1 CDJ38865.1 - 0.0062 16.9 0.6 0.008 16.5 0.6 1.3 1 0 0 1 1 1 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase CHAD PF05235.14 CDJ38865.1 - 0.021 14.8 7.0 0.051 13.6 1.3 2.0 1 1 1 2 2 2 0 CHAD domain Ribonuc_red_sm PF00268.21 CDJ38865.1 - 0.027 14.0 0.0 0.03 13.8 0.0 1.0 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain Mrpl_C PF18502.1 CDJ38865.1 - 0.069 13.4 5.0 0.081 13.2 5.0 1.1 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain DUF4199 PF13858.6 CDJ38865.1 - 0.077 13.4 0.7 0.096 13.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) N1221 PF07923.13 CDJ38865.1 - 0.11 11.7 3.7 0.13 11.4 3.7 1.0 1 0 0 1 1 1 0 N1221-like protein Spt20 PF12090.8 CDJ38865.1 - 0.23 11.1 20.0 0.27 10.8 20.0 1.0 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ38865.1 - 1.2 9.1 14.9 1.2 9.0 14.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FTZ PF03867.14 CDJ38865.1 - 1.9 7.9 5.9 2.4 7.6 5.9 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region DUF3533 PF12051.8 CDJ38865.1 - 4.1 6.2 7.5 5.1 5.9 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) CheD PF03975.13 CDJ38867.1 - 0.0054 16.8 0.1 0.0076 16.3 0.1 1.2 1 0 0 1 1 1 1 CheD chemotactic sensory transduction Spt20 PF12090.8 CDJ38868.1 - 0.0015 18.2 40.4 0.035 13.7 13.1 3.3 3 0 0 3 3 3 2 Spt20 family BTB_2 PF02214.22 CDJ38870.1 - 3.9e-14 52.8 2.6 3.9e-14 52.8 0.1 2.1 2 1 0 2 2 2 1 BTB/POZ domain UPF0240 PF06784.11 CDJ38870.1 - 0.048 13.7 10.2 0.065 13.3 10.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) AAA_11 PF13086.6 CDJ38870.1 - 0.79 9.5 11.7 1 9.1 11.7 1.1 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 CDJ38870.1 - 0.92 10.0 26.6 1.5 9.3 26.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF740 PF05340.12 CDJ38870.1 - 1.1 8.0 12.9 1.3 7.7 12.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) FapA PF03961.13 CDJ38870.1 - 2.5 6.6 10.7 3.1 6.3 10.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 CDJ38870.1 - 2.8 7.1 9.0 3.9 6.6 9.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein VIT1 PF01988.19 CDJ38870.1 - 4.1 7.2 5.7 5.5 6.8 5.7 1.2 1 0 0 1 1 1 0 VIT family Band_3_cyto PF07565.13 CDJ38870.1 - 5.2 6.8 11.5 6.9 6.4 11.4 1.3 1 1 0 1 1 1 0 Band 3 cytoplasmic domain Membralin PF09746.9 CDJ38870.1 - 5.5 5.9 8.3 6.5 5.7 8.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Exonuc_VII_L PF02601.15 CDJ38870.1 - 7 6.1 12.2 8 5.9 12.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 CDJ38870.1 - 7.4 5.6 13.5 8.6 5.3 13.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Calc_CGRP_IAPP PF00214.19 CDJ38871.1 - 0.64 10.4 6.7 0.048 14.0 1.4 1.7 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family Ank_2 PF12796.7 CDJ38873.1 - 3.2e-06 27.7 12.5 3.3e-06 27.6 0.3 3.8 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ38873.1 - 1.4e-05 25.6 6.9 3.5e-05 24.2 0.1 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ38873.1 - 0.0002 21.6 1.9 0.079 13.3 0.1 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ38873.1 - 0.00028 21.1 8.8 0.53 11.0 0.1 5.4 6 0 0 6 6 6 2 Ankyrin repeat RLL PF10036.9 CDJ38873.1 - 0.47 10.3 4.9 0.35 10.7 3.1 1.6 1 1 1 2 2 2 0 RNA transcription, translation and transport factor protein SUIM_assoc PF16619.5 CDJ38874.1 - 0.071 13.2 0.1 0.071 13.2 0.1 9.9 7 2 2 9 9 9 0 Unstructured region C-term to UIM in Ataxin3 Shadoo PF14999.6 CDJ38875.1 - 0.075 13.1 2.8 0.17 12.0 2.8 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective RskA PF10099.9 CDJ38876.1 - 0.015 15.6 8.3 0.015 15.6 8.3 3.2 2 2 0 3 3 3 0 Anti-sigma-K factor rskA MITF_TFEB_C_3_N PF15951.5 CDJ38876.1 - 1.7 9.2 17.4 6.2 7.4 6.2 2.5 2 0 0 2 2 2 0 MITF/TFEB/TFEC/TFE3 N-terminus Spt20 PF12090.8 CDJ38876.1 - 6.5 6.3 15.1 1.8 8.1 8.7 2.1 2 0 0 2 2 2 0 Spt20 family UPF0020 PF01170.18 CDJ38878.1 - 6.2e-06 26.0 0.0 6.2e-06 26.0 0.0 2.2 2 0 0 2 2 1 1 Putative RNA methylase family UPF0020 CDC45 PF02724.14 CDJ38878.1 - 0.00048 18.6 14.7 0.00078 17.9 14.7 1.2 1 0 0 1 1 1 1 CDC45-like protein Tim54 PF11711.8 CDJ38878.1 - 0.0012 17.7 16.2 0.0034 16.2 16.2 1.7 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF4746 PF15928.5 CDJ38878.1 - 0.0044 16.5 16.3 0.0093 15.4 16.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) Hid1 PF12722.7 CDJ38878.1 - 0.016 13.4 15.7 0.021 13.0 15.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RskA PF10099.9 CDJ38878.1 - 0.02 15.2 0.4 0.02 15.2 0.4 6.4 3 2 1 5 5 3 0 Anti-sigma-K factor rskA Exonuc_VII_L PF02601.15 CDJ38878.1 - 0.033 13.7 18.7 3.7 7.0 18.9 2.5 2 1 0 2 2 2 0 Exonuclease VII, large subunit DUF4045 PF13254.6 CDJ38878.1 - 0.11 12.1 20.5 0.22 11.1 20.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) NPR3 PF03666.13 CDJ38878.1 - 0.14 10.9 20.9 0.22 10.3 20.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Velvet PF11754.8 CDJ38878.1 - 0.21 11.5 16.0 0.023 14.7 11.1 2.0 2 0 0 2 2 2 0 Velvet factor DUF913 PF06025.12 CDJ38878.1 - 0.25 10.3 12.2 0.41 9.6 12.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 CDJ38878.1 - 0.27 10.4 12.9 0.42 9.8 12.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter N6_N4_Mtase PF01555.18 CDJ38878.1 - 0.29 10.8 5.0 9.1 5.9 0.0 2.4 2 0 0 2 2 2 0 DNA methylase DUF2151 PF10221.9 CDJ38878.1 - 0.36 9.4 11.2 0.52 8.8 11.2 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator SAPS PF04499.15 CDJ38878.1 - 0.43 9.3 16.5 0.64 8.7 16.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Smg8_Smg9 PF10220.9 CDJ38878.1 - 0.8 7.9 18.6 1.1 7.4 18.6 1.2 1 0 0 1 1 1 0 Smg8_Smg9 AviRa PF11599.8 CDJ38878.1 - 0.87 9.0 0.0 0.87 9.0 0.0 2.8 3 0 0 3 3 1 0 RRNA methyltransferase AviRa GREB1 PF15782.5 CDJ38878.1 - 1.1 6.3 17.9 1.5 5.9 17.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SID-1_RNA_chan PF13965.6 CDJ38878.1 - 1.5 7.2 8.0 1.9 6.8 8.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SelP_N PF04592.14 CDJ38878.1 - 1.6 8.0 22.5 3 7.2 22.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Gti1_Pac2 PF09729.9 CDJ38878.1 - 3.5 7.7 20.5 8.9 6.4 20.5 1.7 1 0 0 1 1 1 0 Gti1/Pac2 family FAM60A PF15396.6 CDJ38878.1 - 4.1 7.3 20.5 11 6.0 20.5 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Plasmodium_Vir PF05795.11 CDJ38878.1 - 7.2 5.9 15.1 12 5.2 15.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein LMBR1 PF04791.16 CDJ38878.1 - 7.6 5.3 9.8 10 4.9 9.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Membralin PF09746.9 CDJ38878.1 - 8.1 5.4 14.7 13 4.7 14.7 1.2 1 0 0 1 1 1 0 Tumour-associated protein Endostatin PF06482.11 CDJ38878.1 - 9.1 5.6 22.8 0.76 9.2 18.1 1.6 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin MFS_1 PF07690.16 CDJ38879.1 - 0.036 13.0 10.4 0.053 12.4 9.7 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily tRNA-synt_1 PF00133.22 CDJ38881.1 - 4.5e-188 626.3 0.0 8e-187 622.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ38881.1 - 8.5e-35 120.0 0.0 7e-34 117.0 0.0 2.3 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ38881.1 - 1.2e-16 60.5 0.3 6.9e-08 31.6 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CDJ38881.1 - 2.6e-08 33.6 0.0 1.2e-06 28.2 0.0 2.4 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 CDJ38881.1 - 0.00049 20.3 7.1 0.0014 18.8 7.1 1.9 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1b PF00579.25 CDJ38881.1 - 0.0033 16.8 0.0 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 CDJ38881.1 - 0.035 13.0 0.0 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 CDJ38881.1 - 0.041 13.2 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.21 CDJ38881.1 - 0.059 12.3 0.0 0.16 10.9 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Mito_fiss_reg PF05308.11 CDJ38881.1 - 0.064 13.3 3.5 0.11 12.5 3.5 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator 4HBT PF03061.22 CDJ38883.1 - 0.017 15.5 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase superfamily Protamine_P2 PF00841.19 CDJ38883.1 - 0.045 14.2 0.1 5.9 7.5 0.1 2.2 2 0 0 2 2 2 0 Sperm histone P2 4HBT_2 PF13279.6 CDJ38883.1 - 0.075 13.5 0.0 0.088 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF2184 PF09950.9 CDJ38883.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2184) Pkinase PF00069.25 CDJ38884.1 - 2.3e-61 207.5 0.0 2.8e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ38884.1 - 2.5e-26 92.5 0.0 4.8e-26 91.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ38884.1 - 3.7e-06 26.5 0.0 0.0005 19.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CDJ38884.1 - 0.0076 16.2 0.1 0.046 13.7 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ38884.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CDJ38884.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 CDJ38884.1 - 0.096 12.3 0.0 0.25 10.9 0.0 1.6 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 eIF-3_zeta PF05091.12 CDJ38885.1 - 1.8 7.4 7.4 2 7.3 7.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EphA2_TM PF14575.6 CDJ38885.1 - 7.6 7.5 0.0 7.6 7.5 0.0 2.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SOBP PF15279.6 CDJ38886.1 - 2.2 8.8 23.3 3 8.3 23.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.9 CDJ38886.1 - 2.5 6.2 32.6 3.6 5.8 32.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0492 PF15744.5 CDJ38886.1 - 3.2 6.9 30.6 5.5 6.1 30.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 SOG2 PF10428.9 CDJ38886.1 - 6.5 5.8 28.2 8.5 5.5 28.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4521 PF15021.6 CDJ38887.1 - 0.011 15.6 0.3 0.013 15.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) DUF3043 PF11241.8 CDJ38887.1 - 0.028 14.5 0.7 0.038 14.0 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) ETRAMP PF09716.10 CDJ38887.1 - 0.046 13.8 0.4 0.046 13.8 0.4 1.8 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Chi-conotoxin PF16981.5 CDJ38887.1 - 0.14 12.4 0.3 0.14 12.4 0.3 2.2 1 1 1 2 2 2 0 chi-Conotoxin or t superfamily DUF3138 PF11336.8 CDJ38887.1 - 0.17 10.5 18.0 0.2 10.2 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DnaJ PF00226.31 CDJ38888.1 - 6.9e-15 54.9 0.0 4.5e-14 52.3 0.0 2.2 1 1 0 1 1 1 1 DnaJ domain Snf7 PF03357.21 CDJ38889.1 - 0.0022 17.6 1.4 0.0032 17.1 1.4 1.3 1 1 0 1 1 1 1 Snf7 DUF812 PF05667.11 CDJ38890.1 - 0.0022 16.9 1.2 0.0027 16.7 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) SAC3_GANP PF03399.16 CDJ38890.1 - 0.0024 17.3 2.1 0.0032 16.9 2.1 1.2 1 0 0 1 1 1 1 SAC3/GANP family OmpH PF03938.14 CDJ38890.1 - 0.0067 16.8 4.5 0.016 15.5 4.5 1.6 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF4618 PF15397.6 CDJ38890.1 - 0.0067 15.9 4.5 0.01 15.3 4.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) YPEB PF14620.6 CDJ38890.1 - 0.031 13.6 1.0 0.054 12.8 1.0 1.3 1 0 0 1 1 1 0 YpeB sporulation AAA_23 PF13476.6 CDJ38890.1 - 0.041 14.4 1.2 0.053 14.0 1.2 1.3 1 0 0 1 1 1 0 AAA domain DUF3573 PF12097.8 CDJ38890.1 - 0.042 12.7 2.1 0.054 12.3 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Spc24 PF08286.11 CDJ38890.1 - 0.065 13.5 1.0 0.12 12.6 1.0 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4140 PF13600.6 CDJ38890.1 - 0.14 12.6 0.8 0.28 11.6 0.8 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF5320 PF17253.2 CDJ38890.1 - 0.16 13.0 0.4 0.52 11.4 0.4 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DUF4279 PF14106.6 CDJ38890.1 - 0.19 11.9 0.8 0.34 11.1 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) TMPIT PF07851.13 CDJ38890.1 - 0.37 10.0 4.1 0.56 9.4 4.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF3138 PF11336.8 CDJ38890.1 - 0.42 9.2 2.7 0.65 8.5 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) YlqD PF11068.8 CDJ38890.1 - 0.48 10.8 12.9 0.23 11.8 9.7 2.0 2 0 0 2 2 2 0 YlqD protein MCU PF04678.13 CDJ38890.1 - 0.79 9.8 4.3 1.6 8.8 4.2 1.5 1 1 0 1 1 1 0 Mitochondrial calcium uniporter HR1 PF02185.16 CDJ38890.1 - 0.89 9.7 13.4 2.2 8.4 11.8 2.2 2 0 0 2 2 2 0 Hr1 repeat FlxA PF14282.6 CDJ38890.1 - 0.97 9.5 21.9 2.7 8.0 21.9 1.7 1 0 0 1 1 1 0 FlxA-like protein PspB PF06667.12 CDJ38890.1 - 1.6 8.9 4.4 3.2 7.9 4.4 1.4 1 0 0 1 1 1 0 Phage shock protein B GIT1_C PF12205.8 CDJ38890.1 - 1.8 8.7 8.6 0.94 9.6 5.9 1.9 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF2205 PF10224.9 CDJ38890.1 - 2.4 8.2 7.5 5.5 7.1 7.5 1.6 1 0 0 1 1 1 0 Short coiled-coil protein DUF4407 PF14362.6 CDJ38890.1 - 2.8 7.2 6.2 0.25 10.6 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Sec2p PF06428.11 CDJ38890.1 - 3.4 7.7 9.5 2.7 8.0 7.7 1.7 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p bZIP_Maf PF03131.17 CDJ38890.1 - 6.4 7.4 15.4 6 7.5 10.3 2.4 2 0 0 2 2 2 0 bZIP Maf transcription factor PAS_3 PF08447.12 CDJ38891.1 - 0.02 15.2 0.0 3.2 8.1 0.0 2.3 2 0 0 2 2 2 0 PAS fold Pkinase PF00069.25 CDJ38894.1 - 8.2e-20 71.3 0.0 2.9e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 CDJ38894.1 - 1.7e-15 57.1 0.0 9.7e-10 38.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_Tyr PF07714.17 CDJ38894.1 - 5.7e-05 22.5 0.0 0.00018 20.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase ACBP PF00887.19 CDJ38895.1 - 2.8e-24 85.1 0.0 4.8e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 CDJ38895.1 - 1.9e-13 50.3 0.1 6.9e-07 29.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ38895.1 - 7.9e-12 45.1 0.1 2.5e-05 24.5 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 CDJ38895.1 - 1.5e-11 44.7 0.1 2.8e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ38895.1 - 1.2e-08 34.5 0.1 0.0039 17.6 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CDJ38895.1 - 1.8e-08 34.7 0.0 0.00063 20.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PTPRCAP PF15713.5 CDJ38896.1 - 1.1 9.6 11.9 0.19 12.0 4.8 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Baculo_F PF12259.8 CDJ38898.1 - 0.54 8.7 2.8 0.81 8.1 2.8 1.1 1 0 0 1 1 1 0 Baculovirus F protein PseudoU_synth_2 PF00849.22 CDJ38899.1 - 4.3e-24 85.4 0.0 7e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ribosomal_L33 PF00471.20 CDJ38900.1 - 3.1e-08 33.9 1.0 5.8e-08 33.1 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L33 Diphthami_syn_2 PF01902.17 CDJ38904.1 - 1.8e-19 70.1 0.0 3.5e-19 69.2 0.0 1.5 1 1 0 1 1 1 1 Diphthamide synthase AAA PF00004.29 CDJ38905.1 - 1.2e-28 100.1 0.1 2.7e-28 99.0 0.1 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ38905.1 - 8.2e-08 31.9 0.0 2.6e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CDJ38905.1 - 1.8e-07 31.1 3.7 1.4e-06 28.2 0.3 2.8 2 1 1 3 3 3 2 Vps4 C terminal oligomerisation domain DnaJ PF00226.31 CDJ38906.1 - 2.5e-19 69.2 7.4 1e-18 67.2 1.1 3.3 2 2 0 2 2 2 1 DnaJ domain GYF PF02213.16 CDJ38907.1 - 3.9e-09 36.0 0.0 8.9e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 GYF domain Pkinase PF00069.25 CDJ38908.1 - 6.9e-18 64.9 0.0 3.3e-15 56.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ38908.1 - 1.6e-10 40.7 0.0 2.7e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ38908.1 - 1.6e-09 37.5 0.9 1.1e-06 28.2 0.0 2.1 2 0 0 2 2 2 2 Kinase-like DUF4259 PF14078.6 CDJ38908.1 - 0.59 10.9 5.2 0.28 11.9 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) MOZ_SAS PF01853.18 CDJ38909.1 - 1.7e-52 177.7 0.1 5.9e-37 127.1 0.4 2.2 1 1 1 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 CDJ38909.1 - 6.3e-20 70.5 1.1 1.3e-19 69.5 1.1 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CDJ38909.1 - 2.6e-09 36.8 0.0 6.1e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain DUF4590 PF15257.6 CDJ38909.1 - 0.0018 18.2 2.4 0.0059 16.5 2.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4590) LEA_3 PF03242.13 CDJ38909.1 - 0.1 13.3 0.2 0.1 13.3 0.2 3.2 2 1 1 3 3 3 0 Late embryogenesis abundant protein Ribosomal_S16 PF00886.19 CDJ38910.1 - 1.2e-16 60.5 0.0 2e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 FAM199X PF15814.5 CDJ38911.1 - 0.0011 18.1 18.5 0.0011 18.1 18.5 5.3 6 0 0 6 6 6 2 Protein family FAM199X Pkinase PF00069.25 CDJ38912.1 - 4.6e-16 59.0 0.0 8.5e-14 51.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 CDJ38912.1 - 6.2e-11 42.1 0.0 2.8e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ38912.1 - 2.5e-06 27.0 0.0 5.4e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase MCM PF00493.23 CDJ38913.1 - 3.1e-78 261.9 0.0 3.6e-50 170.2 0.1 3.4 2 1 1 3 3 3 3 MCM P-loop domain MCM_OB PF17207.3 CDJ38913.1 - 2.5e-30 104.9 0.1 6e-30 103.7 0.1 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDJ38913.1 - 5.2e-25 87.7 0.6 3.5e-24 85.0 0.4 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain MCM6_C PF18263.1 CDJ38913.1 - 3e-08 33.8 0.1 1.3e-07 31.8 0.1 2.1 1 1 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 CDJ38913.1 - 3.9e-06 27.4 0.0 4.5e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 CDJ38913.1 - 0.19 11.7 0.0 0.51 10.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Clathrin_lg_ch PF01086.17 CDJ38914.1 - 3.8e-09 36.9 15.7 3.8e-09 36.9 15.7 2.2 2 1 0 2 2 2 1 Clathrin light chain LMBR1 PF04791.16 CDJ38914.1 - 0.13 11.1 0.2 0.17 10.8 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Esterase PF00756.20 CDJ38914.1 - 0.21 11.2 3.3 1.4 8.5 1.2 2.1 2 0 0 2 2 2 0 Putative esterase AAA_11 PF13086.6 CDJ38914.1 - 4 7.2 14.3 0.78 9.5 5.8 2.1 2 0 0 2 2 2 0 AAA domain tRNA-synt_2 PF00152.20 CDJ38915.1 - 1.3e-38 132.8 0.0 4.3e-25 88.5 0.0 3.0 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CDJ38915.1 - 0.00061 19.3 0.1 0.36 10.3 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 CDJ38915.1 - 0.011 15.7 0.0 0.042 13.8 0.0 1.9 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain SUIM_assoc PF16619.5 CDJ38915.1 - 0.17 12.0 0.1 0.17 12.0 0.1 9.6 8 1 0 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 DUF1645 PF07816.11 CDJ38915.1 - 0.45 11.1 21.8 1.3 9.6 2.6 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) DUF3446 PF11928.8 CDJ38916.1 - 0.016 15.5 28.2 0.16 12.3 9.7 3.8 4 0 0 4 4 4 0 Early growth response N-terminal domain IMUP PF15761.5 CDJ38916.1 - 0.62 10.8 26.3 3.7 8.3 1.3 3.7 3 0 0 3 3 3 0 Immortalisation up-regulated protein SUZ PF12752.7 CDJ38916.1 - 5.8 7.7 11.4 1.6 9.5 2.1 2.9 3 0 0 3 3 3 0 SUZ domain ERCC4 PF02732.15 CDJ38917.1 - 5.7e-13 49.4 0.0 5.7e-13 49.4 0.0 2.8 4 0 0 4 4 4 1 ERCC4 domain SR-25 PF10500.9 CDJ38917.1 - 0.0098 15.5 0.7 0.0098 15.5 0.7 6.6 7 0 0 7 7 7 3 Nuclear RNA-splicing-associated protein GCFC PF07842.12 CDJ38918.1 - 1.2e-32 113.6 11.4 1.2e-32 113.6 11.4 2.1 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 CDJ38918.1 - 4.6e-08 32.8 0.9 4.6e-08 32.8 0.9 2.1 2 0 0 2 2 2 1 G-patch domain TIP_N PF12457.8 CDJ38918.1 - 0.00049 20.4 8.4 0.00049 20.4 8.4 5.2 2 2 3 5 5 5 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 CDJ38918.1 - 0.067 13.3 0.1 0.36 11.0 0.1 2.4 1 0 0 1 1 1 0 G-patch domain MRP-S31 PF15433.6 CDJ38919.1 - 2.7 7.6 19.6 4.5 6.9 19.3 1.6 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 LAP1C PF05609.12 CDJ38919.1 - 6.5 5.7 21.7 0.4 9.7 17.0 1.4 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) bMG3 PF11974.8 CDJ38921.1 - 0.03 14.3 0.5 0.26 11.3 0.1 2.6 2 0 0 2 2 2 0 Bacterial alpha-2-macroglobulin MG3 domain TatD_DNase PF01026.21 CDJ38922.1 - 1.3e-42 145.9 0.0 2e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase SUIM_assoc PF16619.5 CDJ38922.1 - 0.0021 18.1 15.3 0.0046 17.0 5.7 3.3 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ38922.1 - 0.044 13.4 9.0 0.26 10.9 2.4 2.2 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.9 CDJ38922.1 - 5.1 6.6 13.8 1e+02 2.4 0.1 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Scaffolding_pro PF11418.8 CDJ38923.1 - 0.62 10.7 2.6 9.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Phi29 scaffolding protein P16-Arc PF04699.14 CDJ38924.1 - 1.8 9.1 5.4 1.9 9.0 0.9 3.1 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) NTF2 PF02136.20 CDJ38926.1 - 4.6e-16 59.5 0.0 4.6e-16 59.5 0.0 1.8 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain AP2 PF00847.20 CDJ38927.1 - 4.3e-09 36.5 0.2 8.5e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 AP2 domain C2 PF00168.30 CDJ38928.1 - 4.4e-34 116.9 0.2 1.4e-06 28.5 0.0 6.5 6 0 0 6 6 6 6 C2 domain Ferlin_C PF16165.5 CDJ38928.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Ferlin C-terminus ERM PF00769.19 CDJ38929.1 - 0.045 13.6 13.7 0.074 12.9 13.7 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHODB_Fe-S_bind PF10418.9 CDJ38929.1 - 0.97 9.3 6.6 2.3 8.1 6.6 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B ADIP PF11559.8 CDJ38929.1 - 5.4 7.1 13.7 9.6 6.3 13.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Pyr_redox_2 PF07992.14 CDJ38931.1 - 1.5e-72 244.3 2.2 2.3e-72 243.7 2.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ38931.1 - 1.4e-35 121.8 0.1 4.4e-35 120.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDJ38931.1 - 2.1e-23 82.6 5.9 2.3e-20 72.9 0.5 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ38931.1 - 5.7e-11 42.4 4.8 6.2e-11 42.3 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CDJ38931.1 - 2.7e-10 40.0 1.2 7.5e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDJ38931.1 - 2.3e-08 33.5 5.7 3.5e-08 33.0 1.5 2.6 2 1 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 CDJ38931.1 - 1e-07 31.0 5.8 0.00011 21.0 0.2 3.7 3 1 1 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.24 CDJ38931.1 - 2.8e-07 30.0 3.6 2.8e-07 30.0 3.6 3.2 3 1 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 CDJ38931.1 - 9.7e-07 28.2 0.1 0.038 13.1 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 CDJ38931.1 - 2.1e-06 27.3 9.9 0.01 15.1 0.9 3.2 2 1 1 3 3 3 3 FAD binding domain AlaDh_PNT_C PF01262.21 CDJ38931.1 - 1e-05 24.9 3.5 0.011 15.1 0.2 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CDJ38931.1 - 1.2e-05 25.1 10.0 0.075 12.6 0.0 3.6 4 0 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 CDJ38931.1 - 2.7e-05 23.6 1.8 3.8e-05 23.0 0.0 2.1 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.6 CDJ38931.1 - 8.2e-05 22.8 8.0 0.00065 19.9 1.5 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 CDJ38931.1 - 0.054 13.4 0.1 0.054 13.4 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 CDJ38931.1 - 0.11 11.5 2.7 0.6 9.1 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 CDJ38931.1 - 0.16 12.4 1.0 3.3 8.2 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Peptidase_S9 PF00326.21 CDJ38932.1 - 2.7e-07 30.3 0.2 0.015 14.8 0.2 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ38932.1 - 7.7e-07 29.0 0.3 1.6e-05 24.7 0.3 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CDJ38932.1 - 1.1e-06 28.5 0.2 5e-06 26.3 0.2 1.9 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 CDJ38932.1 - 9.5e-05 21.8 0.2 0.024 13.9 0.3 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 PhoPQ_related PF10142.9 CDJ38932.1 - 0.00027 19.7 0.0 0.00045 19.0 0.0 1.3 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_6 PF12697.7 CDJ38932.1 - 0.0012 19.5 0.0 0.0095 16.6 0.0 1.9 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CDJ38932.1 - 0.04 13.8 2.7 0.056 13.3 0.1 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold VirJ PF06057.11 CDJ38932.1 - 0.048 13.5 0.1 0.081 12.8 0.1 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Peptidase_S9_N PF02897.15 CDJ38933.1 - 2.3e-105 352.8 0.1 3.2e-105 352.3 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CDJ38933.1 - 3.5e-57 193.3 0.0 6.1e-57 192.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4227 PF14004.6 CDJ38933.1 - 0.049 13.6 0.0 0.18 11.8 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) Abhydrolase_3 PF07859.13 CDJ38933.1 - 0.053 13.4 0.1 0.26 11.1 0.1 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 CDJ38933.1 - 0.084 12.5 0.1 1 8.9 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.11 CDJ38933.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal zf-C2HC_2 PF13913.6 CDJ38934.1 - 1.8e-09 37.3 7.1 5.3e-05 23.0 1.0 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 CDJ38934.1 - 0.00061 20.1 8.5 0.076 13.5 0.2 3.4 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CDJ38934.1 - 0.0093 16.2 6.8 0.07 13.4 0.2 3.7 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CDJ38934.1 - 0.03 15.1 16.4 0.23 12.4 0.2 3.9 3 1 1 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDJ38934.1 - 0.057 13.2 5.5 0.16 11.8 0.1 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-Di19 PF05605.12 CDJ38934.1 - 0.074 13.4 0.3 0.074 13.4 0.3 1.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TPR_MLP1_2 PF07926.12 CDJ38937.1 - 6.1e-05 23.1 14.9 6.1e-05 23.1 14.9 7.0 3 1 2 6 6 6 2 TPR/MLP1/MLP2-like protein HalX PF08663.10 CDJ38937.1 - 0.037 14.3 0.4 0.037 14.3 0.4 9.9 5 4 5 10 10 10 0 HalX domain Baculo_PEP_C PF04513.12 CDJ38937.1 - 0.074 13.1 18.0 0.59 10.2 3.2 4.7 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 CDJ38937.1 - 2.8 8.5 26.7 27 5.3 0.0 7.6 5 2 2 7 7 7 0 Nucleopolyhedrovirus P10 protein EELM2 PF15863.5 CDJ38938.1 - 3.7e-63 212.7 0.0 6e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Extended EGL-27 and MTA1 homology domain Pre-PUA PF17832.1 CDJ38939.1 - 1.3e-25 89.9 0.1 1.9e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CDJ38939.1 - 2.7e-14 52.9 0.0 3.8e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 PUA domain ATP-grasp_6 PF18419.1 CDJ38939.1 - 0.027 14.1 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp-like domain S10_plectin PF03501.15 CDJ38940.1 - 2e-41 140.0 0.6 2.5e-41 139.7 0.6 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF2250 PF10007.9 CDJ38940.1 - 0.11 12.6 0.2 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) zf-CCCH PF00642.24 CDJ38941.1 - 7.6e-09 35.3 19.9 0.00014 21.6 1.9 3.5 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CDJ38941.1 - 0.00036 20.7 3.9 0.0014 18.8 0.8 2.2 2 0 0 2 2 2 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 CDJ38941.1 - 0.00097 19.1 4.9 0.00097 19.1 4.9 4.5 5 0 0 5 5 5 1 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ38941.1 - 0.0013 18.4 3.5 0.0013 18.4 3.5 3.7 3 1 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 CDJ38941.1 - 0.0022 18.7 11.5 0.0092 16.7 1.3 2.9 1 1 2 3 3 3 2 Torus domain zf-C3H1 PF10650.9 CDJ38941.1 - 0.012 15.4 6.0 6.6 6.6 0.2 3.3 3 0 0 3 3 3 0 Putative zinc-finger domain zf-CCCH_2 PF14608.6 CDJ38941.1 - 0.15 12.6 19.3 0.84 10.2 1.2 3.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Disintegrin PF00200.23 CDJ38941.1 - 4.4 8.2 9.7 17 6.3 0.7 2.3 1 1 1 2 2 2 0 Disintegrin Aldedh PF00171.22 CDJ38942.1 - 0.0035 15.9 1.9 0.02 13.4 0.0 2.5 3 0 0 3 3 3 2 Aldehyde dehydrogenase family PCRF PF03462.18 CDJ38943.1 - 4.3e-30 105.0 6.5 4.3e-30 105.0 6.5 2.5 2 1 0 2 2 2 1 PCRF domain RF-1 PF00472.20 CDJ38943.1 - 3.3e-28 98.0 1.6 3.3e-28 98.0 1.6 2.5 3 0 0 3 3 3 1 RF-1 domain DUF3740 PF12548.8 CDJ38943.1 - 3.9 7.9 6.8 0.91 9.9 0.1 2.8 3 0 0 3 3 3 0 Sulfatase protein RskA PF10099.9 CDJ38944.1 - 0.009 16.3 11.1 0.009 16.3 11.1 6.4 4 2 2 6 6 6 3 Anti-sigma-K factor rskA Dehydrin PF00257.19 CDJ38948.1 - 0.012 16.2 3.9 0.012 16.2 3.9 2.1 2 1 0 2 2 2 0 Dehydrin FHIPEP PF00771.20 CDJ38948.1 - 0.23 9.9 4.9 0.31 9.5 4.9 1.2 1 0 0 1 1 1 0 FHIPEP family Nop25 PF09805.9 CDJ38948.1 - 0.94 9.9 16.8 0.14 12.7 10.9 2.0 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) SR-25 PF10500.9 CDJ38948.1 - 1.5 8.4 15.6 0.22 11.1 11.9 1.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PGA2 PF07543.12 CDJ38948.1 - 3.4 7.7 11.8 2.2 8.3 8.2 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF2229 PF09989.9 CDJ38948.1 - 4.8 6.8 5.9 6.9 6.3 2.1 2.2 2 1 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Afi1 PF07792.12 CDJ38948.1 - 5 7.6 8.3 1.6 9.2 5.0 1.7 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CSRNP_N PF16019.5 CDJ38948.1 - 5.8 6.8 12.6 0.57 10.1 6.6 1.9 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus EBP50_C PF09007.11 CDJ38948.1 - 6.7 7.7 12.8 4.8 8.2 9.3 2.0 2 0 0 2 2 2 0 EBP50, C-terminal RskA PF10099.9 CDJ38949.1 - 1.1 9.6 44.0 0.15 12.4 10.3 4.6 1 1 3 4 4 4 0 Anti-sigma-K factor rskA RRM_1 PF00076.22 CDJ38950.1 - 0.011 15.6 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.26 CDJ38951.1 - 2.3e-13 50.0 0.0 3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDJ38951.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain EMP70 PF02990.16 CDJ38952.1 - 0.15 10.7 2.3 1.2 7.7 0.4 2.3 2 0 0 2 2 2 0 Endomembrane protein 70 FliP PF00813.20 CDJ38952.1 - 0.22 11.4 3.1 0.31 10.9 0.1 2.4 2 0 0 2 2 2 0 FliP family Acyl_transf_3 PF01757.22 CDJ38952.1 - 2 7.4 14.8 0.096 11.7 7.2 2.4 3 0 0 3 3 3 0 Acyltransferase family TFIIA PF03153.13 CDJ38952.1 - 7.8 6.4 47.8 3.1 7.7 6.9 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit EphA2_TM PF14575.6 CDJ38952.1 - 10 7.1 8.5 21 6.1 0.0 4.1 4 1 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain NAP PF00956.18 CDJ38953.1 - 3.6e-52 177.2 0.0 3.6e-52 177.2 0.0 4.7 3 2 0 3 3 3 1 Nucleosome assembly protein (NAP) MRP_L53 PF10780.9 CDJ38955.1 - 0.0087 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 LPD29 PF18847.1 CDJ38955.1 - 0.092 13.7 0.0 0.11 13.4 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 29 cNMP_binding PF00027.29 CDJ38958.1 - 4e-14 52.4 0.1 8.6e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kelch_4 PF13418.6 CDJ38960.1 - 2.1e-39 133.3 3.3 3.9e-08 33.2 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ38960.1 - 3.5e-27 94.1 6.9 3.3e-07 30.4 0.0 7.7 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ38960.1 - 5.1e-25 87.0 0.0 7.2e-05 22.7 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CDJ38960.1 - 1.5e-20 72.7 3.0 8.5e-05 22.7 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 CDJ38960.1 - 3.6e-17 61.7 5.0 0.00062 19.3 0.0 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 CDJ38960.1 - 2.2e-07 30.6 12.2 0.0045 16.9 0.0 6.7 7 1 0 7 7 7 2 Kelch motif APG6_N PF17675.1 CDJ38960.1 - 0.0021 18.6 6.6 0.0037 17.8 6.6 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF948 PF06103.11 CDJ38960.1 - 0.021 15.1 4.0 0.021 15.1 4.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec34 PF04136.15 CDJ38960.1 - 0.027 14.4 2.9 0.049 13.5 2.9 1.4 1 0 0 1 1 1 0 Sec34-like family GAT PF03127.14 CDJ38960.1 - 0.032 14.5 1.9 0.059 13.7 1.9 1.4 1 0 0 1 1 1 0 GAT domain TMPIT PF07851.13 CDJ38960.1 - 0.11 11.7 5.2 0.17 11.1 5.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein Lebercilin PF15619.6 CDJ38960.1 - 0.14 11.8 9.4 0.23 11.1 9.4 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease YscO PF07321.12 CDJ38960.1 - 0.21 11.6 10.3 0.37 10.7 10.3 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO GAS PF13851.6 CDJ38960.1 - 0.27 10.5 9.8 0.46 9.8 9.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TF_AP-2 PF03299.14 CDJ38960.1 - 0.29 11.1 7.5 0.19 11.7 3.5 2.0 2 0 0 2 2 2 0 Transcription factor AP-2 Syntaxin-6_N PF09177.11 CDJ38960.1 - 0.56 10.8 5.4 2.1 8.9 5.4 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 CDJ38960.1 - 0.6 10.1 5.9 1.4 8.9 5.9 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vps53_N PF04100.12 CDJ38960.1 - 0.86 8.5 6.2 1.2 8.0 6.2 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal Atg14 PF10186.9 CDJ38960.1 - 0.95 8.5 5.5 1.3 8.0 5.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 CDJ38960.1 - 1.3 8.3 15.2 0.87 8.8 11.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) WXG100 PF06013.12 CDJ38960.1 - 1.3 9.3 10.3 5.4 7.3 10.1 2.1 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Spc7 PF08317.11 CDJ38960.1 - 1.8 7.4 13.2 2.6 6.9 13.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 CDJ38960.1 - 3.4 7.8 7.8 7.3 6.8 7.8 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 CDJ38960.1 - 3.9 7.8 10.8 8.5 6.8 4.7 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BRE1 PF08647.11 CDJ38960.1 - 5.4 7.2 11.9 9.8 6.3 11.9 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase KxDL PF10241.9 CDJ38960.1 - 6.9 7.0 10.3 22 5.4 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein DivIC PF04977.15 CDJ38960.1 - 7.3 6.4 6.7 8.8 6.2 0.4 2.5 2 0 0 2 2 2 0 Septum formation initiator Nudc_N PF14050.6 CDJ38961.1 - 2e-18 66.1 0.0 3.4e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 CDJ38961.1 - 1.1e-06 29.5 0.8 1.6e-05 25.8 0.8 2.3 1 1 0 1 1 1 1 CS domain RAP1 PF07218.11 CDJ38961.1 - 1.3 7.2 4.0 2 6.6 4.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ODV-E18 PF10717.9 CDJ38961.1 - 1.4 8.9 3.2 0.67 9.9 0.8 1.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 CDC27 PF09507.10 CDJ38961.1 - 4.8 6.5 16.1 9.3 5.5 16.1 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 eIF2A PF08662.11 CDJ38962.1 - 9.2e-32 110.5 0.0 5.8e-30 104.6 0.0 2.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Med19 PF10278.9 CDJ38962.1 - 0.0036 17.3 7.0 0.75 9.7 5.0 2.9 3 0 0 3 3 3 2 Mediator of RNA pol II transcription subunit 19 BTK PF00779.19 CDJ38963.1 - 0.0057 16.5 8.1 0.0057 16.5 8.1 3.6 4 0 0 4 4 4 1 BTK motif LIM PF00412.22 CDJ38963.1 - 0.19 12.0 11.7 1.8 8.9 0.8 2.3 2 0 0 2 2 2 0 LIM domain Glycos_transf_2 PF00535.26 CDJ38964.1 - 2.8e-16 59.8 0.0 7.9e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ38964.1 - 4.6e-08 33.4 1.2 1.2e-07 32.0 1.2 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CDJ38964.1 - 0.00013 21.6 0.1 0.00028 20.5 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 CDJ38964.1 - 0.00093 19.9 0.8 0.0019 18.9 0.0 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.9 CDJ38964.1 - 0.052 13.0 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 CBF PF03914.17 CDJ38966.1 - 4.8e-10 39.7 2.5 4.8e-10 39.7 2.5 2.4 2 0 0 2 2 2 1 CBF/Mak21 family CRISPR_Cse2 PF09485.10 CDJ38966.1 - 1.8 9.1 8.5 3.2 8.3 0.0 3.4 4 0 0 4 4 4 0 CRISPR-associated protein Cse2 (CRISPR_cse2) rRNA_processing PF08524.11 CDJ38967.1 - 2.9e-06 27.4 25.0 2.9e-06 27.4 25.0 2.8 1 1 0 2 2 2 1 rRNA processing DBR1 PF05011.13 CDJ38968.1 - 1.1e-13 51.8 14.7 3.2e-12 47.0 14.7 2.7 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 CDJ38968.1 - 3.3e-09 37.6 0.5 6.6e-09 36.6 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ38968.1 - 0.00017 21.8 0.0 0.0017 18.6 0.0 2.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain ALMT PF11744.8 CDJ38968.1 - 4.9 5.9 12.5 6.9 5.4 12.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RR_TM4-6 PF06459.12 CDJ38968.1 - 6.3 6.5 19.6 11 5.8 19.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.11 CDJ38968.1 - 9 6.3 23.3 14 5.7 23.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region EF1_GNE PF00736.19 CDJ38969.1 - 4.8e-33 113.2 3.5 7.6e-33 112.6 3.5 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Kri1_C PF12936.7 CDJ38970.1 - 7.7e-25 86.9 1.3 7.7e-25 86.9 1.3 4.5 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 CDJ38970.1 - 2.2e-15 57.0 8.8 2.2e-15 57.0 8.8 5.8 3 2 1 4 4 4 1 KRI1-like family ZZ PF00569.17 CDJ38970.1 - 7.1e-07 28.9 2.8 1.6e-06 27.8 2.8 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type RCC1 PF00415.18 CDJ38971.1 - 1.2e-38 131.5 25.5 3.7e-09 37.1 0.4 6.8 5 2 1 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ38971.1 - 9.5e-09 34.8 35.0 1e-05 25.2 1.9 6.0 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Efg1 PF10153.9 CDJ38971.1 - 0.062 13.7 0.3 0.13 12.7 0.3 1.4 1 0 0 1 1 1 0 rRNA-processing protein Efg1 SUIM_assoc PF16619.5 CDJ38971.1 - 9.4 6.4 11.9 0.025 14.6 1.7 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Actin PF00022.19 CDJ38972.1 - 1.7e-124 415.5 0.0 1e-123 413.0 0.0 1.8 1 1 0 1 1 1 1 Actin Homoserine_dh PF00742.19 CDJ38972.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Homoserine dehydrogenase IBR PF01485.21 CDJ38974.1 - 1.2e-17 63.9 30.7 4.3e-10 39.7 4.2 3.8 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain PPDK_N PF01326.19 CDJ38975.1 - 3.5e-15 56.1 0.0 6.3e-14 52.0 0.0 3.2 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain RPN13_C PF16550.5 CDJ38975.1 - 0.014 15.6 0.1 0.039 14.1 0.1 1.7 1 0 0 1 1 1 0 UCH-binding domain FXMR_C2 PF16098.5 CDJ38975.1 - 0.22 12.1 1.7 0.82 10.2 1.7 1.9 1 0 0 1 1 1 0 Fragile X-related mental retardation protein C-terminal region 2 preATP-grasp_3 PF18301.1 CDJ38975.1 - 1.2 9.5 4.8 0.6 10.4 0.1 3.1 3 0 0 3 3 3 0 pre ATP-grasp 3 domain CSD PF00313.22 CDJ38976.1 - 6.5e-24 83.6 0.4 9e-24 83.1 0.4 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 CDJ38976.1 - 0.00064 19.4 0.8 0.0016 18.1 0.8 1.7 1 1 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.23 CDJ38976.1 - 0.11 12.9 0.1 0.17 12.3 0.1 1.2 1 0 0 1 1 1 0 S1 RNA binding domain PP2C PF00481.21 CDJ38978.1 - 1.5e-35 123.1 0.0 2.2e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ38978.1 - 2e-06 27.9 0.0 3.5e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CDJ38978.1 - 4.6e-05 23.1 0.0 0.0073 16.0 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C Trehalase PF01204.18 CDJ38979.1 - 1.5e-64 218.7 0.0 2e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 CDJ38979.1 - 1.1e-05 24.6 0.2 1.6e-05 24.0 0.2 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DEAD PF00270.29 CDJ38983.1 - 5.8e-45 153.2 0.1 8e-45 152.7 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ38983.1 - 6.2e-29 100.6 1.9 1.1e-28 99.8 0.4 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CDJ38983.1 - 0.044 13.1 0.1 0.081 12.3 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MMR_HSR1 PF01926.23 CDJ38984.1 - 9.7e-38 128.8 0.0 1.6e-18 66.8 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 CDJ38984.1 - 3.6e-25 88.1 0.1 8.1e-25 86.9 0.1 1.7 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 CDJ38984.1 - 2.4e-13 49.9 0.1 9.1e-09 35.0 0.0 3.2 3 1 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDJ38984.1 - 9.4e-12 44.9 0.5 2.1e-05 24.1 0.1 4.6 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CDJ38984.1 - 2.7e-10 40.6 2.6 0.00038 20.6 0.1 4.4 3 1 1 4 4 4 2 Dynamin family AIG1 PF04548.16 CDJ38984.1 - 4.5e-09 35.9 0.2 0.0011 18.3 0.0 2.8 3 1 0 3 3 3 2 AIG1 family RsgA_GTPase PF03193.16 CDJ38984.1 - 1.8e-06 27.9 0.2 0.079 12.9 0.0 4.0 5 0 0 5 5 5 2 RsgA GTPase Roc PF08477.13 CDJ38984.1 - 2.5e-05 24.5 0.1 0.098 12.9 0.0 3.2 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ38984.1 - 0.00033 20.3 0.1 0.15 11.6 0.0 3.3 3 1 0 3 3 3 1 Ras family Gtr1_RagA PF04670.12 CDJ38984.1 - 0.00081 18.8 0.1 0.064 12.6 0.0 2.6 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region TniB PF05621.11 CDJ38984.1 - 0.0016 17.8 0.1 0.23 10.8 0.0 2.7 3 0 0 3 3 3 1 Bacterial TniB protein ABC_tran PF00005.27 CDJ38984.1 - 0.0037 17.8 0.0 3.5 8.1 0.0 3.1 3 0 0 3 3 3 1 ABC transporter Arf PF00025.21 CDJ38984.1 - 0.033 13.6 0.1 0.28 10.6 0.1 2.3 1 1 0 1 1 1 0 ADP-ribosylation factor family Vert_HS_TF PF06546.11 CDJ38984.1 - 0.051 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Vertebrate heat shock transcription factor SRPRB PF09439.10 CDJ38984.1 - 0.052 13.0 0.1 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_15 PF13175.6 CDJ38984.1 - 0.12 12.0 0.0 4.8 6.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Nuc_deoxyrib_tr PF05014.15 CDJ38984.1 - 0.18 11.8 0.5 11 6.0 0.1 2.7 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase Pkinase PF00069.25 CDJ38985.1 - 1e-60 205.4 0.0 1.6e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ38985.1 - 3.9e-36 124.6 0.0 6.5e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ38985.1 - 0.00066 18.6 0.0 0.0025 16.7 0.0 1.9 1 0 0 1 1 1 1 Fungal protein kinase UPF0113_N PF17833.1 CDJ38987.1 - 3.3e-26 91.6 0.1 4.9e-26 91.1 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CDJ38987.1 - 2.7e-16 59.6 0.0 4.4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain DEAD PF00270.29 CDJ38988.1 - 1.4e-25 90.1 0.0 3.5e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ38988.1 - 7.8e-23 80.9 0.0 2.3e-22 79.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ38988.1 - 0.017 15.1 0.3 0.1 12.6 0.0 2.5 2 2 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ38988.1 - 0.14 12.4 0.5 1.3 9.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF4351 PF14261.6 CDJ38988.1 - 0.25 11.4 5.3 0.92 9.6 2.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) Cir_N PF10197.9 CDJ38989.1 - 6.4e-12 45.5 13.0 6.4e-12 45.5 13.0 4.4 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Slu7 PF11708.8 CDJ38989.1 - 2.4 7.8 18.5 4 7.1 12.4 2.8 2 1 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor HSP70 PF00012.20 CDJ38989.1 - 6.3 4.8 10.3 8.6 4.4 10.3 1.1 1 0 0 1 1 1 0 Hsp70 protein V_ATPase_I PF01496.19 CDJ38989.1 - 6.9 4.5 5.5 7.9 4.3 5.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Penicil_amidase PF01804.18 CDJ38991.1 - 9.1e-105 352.1 0.0 1.7e-104 351.2 0.0 1.3 1 1 0 1 1 1 1 Penicillin amidase EF-hand_6 PF13405.6 CDJ38993.1 - 2.5e-10 39.4 0.1 0.00031 20.4 0.0 3.1 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDJ38993.1 - 1.1e-09 37.1 0.0 0.00038 19.8 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CDJ38993.1 - 2.8e-08 34.1 0.1 0.0034 17.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ38993.1 - 1.8e-05 24.5 0.1 0.032 14.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CDJ38993.1 - 0.00071 19.8 0.0 0.46 10.8 0.1 3.1 2 1 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CDJ38993.1 - 0.096 12.2 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 EF hand ASH PF15780.5 CDJ38994.1 - 6e-15 55.2 7.8 0.35 11.1 0.0 8.8 9 0 0 9 9 9 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CDJ38994.1 - 0.00019 21.5 0.2 0.07 13.3 0.0 4.0 4 0 0 4 4 4 1 Flagellar-associated PapD-like MYCBPAP PF14646.6 CDJ38994.1 - 0.026 13.5 0.8 0.059 12.3 0.1 1.9 3 0 0 3 3 3 0 MYCBP-associated protein family DUF1573 PF07610.11 CDJ38994.1 - 0.13 12.3 2.6 65 3.7 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1573) MITF_TFEB_C_3_N PF15951.5 CDJ38995.1 - 9.2e-05 23.1 3.4 0.00022 21.9 3.4 1.6 1 0 0 1 1 1 1 MITF/TFEB/TFEC/TFE3 N-terminus PapD-like PF14874.6 CDJ38996.1 - 0.0012 18.9 0.0 2.3 8.5 0.0 2.9 3 0 0 3 3 3 2 Flagellar-associated PapD-like DUF1573 PF07610.11 CDJ38996.1 - 0.0033 17.4 0.0 17 5.5 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1573) FixG_C PF11614.8 CDJ38996.1 - 0.061 13.5 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase ASH PF15780.5 CDJ38997.1 - 1.5e-12 47.6 0.1 0.024 14.8 0.0 6.4 6 0 0 6 6 6 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CDJ38997.1 - 0.00026 20.8 0.2 3.2 7.6 0.0 5.1 6 0 0 6 6 6 2 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CDJ38997.1 - 0.0017 18.6 0.4 1.7 8.9 0.1 3.6 4 0 0 4 4 4 2 Transmembrane protein 131-like MYCBPAP PF14646.6 CDJ38997.1 - 0.037 13.0 0.1 30 3.4 0.0 3.2 3 0 0 3 3 3 0 MYCBP-associated protein family ASH PF15780.5 CDJ38998.1 - 1.5e-09 37.9 0.0 7.3e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CDJ38998.1 - 0.00011 22.0 0.0 0.088 12.7 0.0 2.8 3 0 0 3 3 3 2 MSP (Major sperm protein) domain PapD-like PF14874.6 CDJ38998.1 - 0.0053 16.9 0.0 0.093 12.9 0.0 2.1 2 0 0 2 2 2 1 Flagellar-associated PapD-like ASH PF15780.5 CDJ38999.1 - 7.6e-06 26.1 0.1 0.025 14.8 0.0 3.0 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FXa_inhibition PF14670.6 CDJ39000.1 - 0.028 14.7 2.1 0.028 14.7 2.1 9.5 8 2 1 9 9 9 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CDJ39000.1 - 0.052 13.5 0.6 0.052 13.5 0.6 7.2 8 0 0 8 8 8 0 Complement Clr-like EGF-like EGF_3 PF12947.7 CDJ39000.1 - 0.98 9.7 60.8 0.058 13.6 2.6 8.9 8 1 0 8 8 8 0 EGF domain Peptidase_M24 PF00557.24 CDJ39001.1 - 5.1e-38 130.9 0.0 7.2e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 CDJ39001.1 - 6.9e-31 107.5 0.0 2.9e-29 102.2 0.0 3.2 3 1 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CDJ39001.1 - 3.6e-24 84.6 0.1 1.5e-23 82.6 0.1 2.2 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CDJ39001.1 - 2e-20 73.8 0.4 3.5e-16 60.0 0.0 2.8 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain zf-U1 PF06220.12 CDJ39002.1 - 0.00043 20.0 0.5 0.00043 20.0 0.5 1.9 2 0 0 2 2 2 1 U1 zinc finger WW PF00397.26 CDJ39002.1 - 0.063 13.4 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 WW domain Ribosomal_S2 PF00318.20 CDJ39002.1 - 0.32 10.2 5.4 0.038 13.2 0.7 1.8 2 0 0 2 2 2 0 Ribosomal protein S2 zf-RING_2 PF13639.6 CDJ39003.1 - 3e-05 24.3 13.7 3e-05 24.3 13.7 3.5 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ39003.1 - 0.00024 20.9 14.2 0.00024 20.9 14.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 CDJ39003.1 - 0.00064 19.7 1.9 0.00064 19.7 1.9 4.7 1 1 4 5 5 5 2 Seven in absentia protein family zf-C3HC4_2 PF13923.6 CDJ39003.1 - 0.0018 18.1 12.8 0.0018 18.1 12.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ39003.1 - 0.0023 17.9 13.5 0.01 15.8 13.5 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-TRAF PF02176.18 CDJ39003.1 - 0.0031 18.2 11.7 0.011 16.4 5.5 4.1 2 1 3 5 5 5 2 TRAF-type zinc finger zf-ANAPC11 PF12861.7 CDJ39003.1 - 0.01 15.9 5.2 0.01 15.9 5.2 2.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CDJ39003.1 - 0.02 15.0 12.5 0.02 15.0 12.5 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-TRAF_2 PF15965.5 CDJ39003.1 - 0.071 13.6 21.7 0.054 14.0 5.1 3.3 1 1 2 3 3 3 0 TRAF-like zinc-finger zf_C2H2_6 PF18450.1 CDJ39003.1 - 7.5 6.4 11.4 9.8 6.0 0.2 3.4 3 1 0 3 3 3 0 Zinc Finger domain OTU PF02338.19 CDJ39004.1 - 3.6e-12 46.9 0.0 7.1e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDJ39004.1 - 0.0022 17.5 0.5 0.8 9.1 0.5 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain ATP-synt_C PF00137.21 CDJ39005.1 - 5.6e-30 103.5 32.3 3.2e-16 59.4 10.1 2.4 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.6 CDJ39005.1 - 0.17 12.3 0.1 0.31 11.5 0.1 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 IMCp PF12314.8 CDJ39006.1 - 2.8e-24 85.2 23.1 2.8e-24 85.2 23.1 3.7 1 1 2 3 3 3 3 Inner membrane complex protein ParA PF10609.9 CDJ39007.1 - 9.3e-69 231.6 0.0 4.9e-46 157.2 0.0 2.2 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 CDJ39007.1 - 3e-17 62.6 0.3 1.1e-16 60.7 0.0 2.1 3 0 0 3 3 3 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 CDJ39007.1 - 5.6e-10 39.4 0.0 9.1e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF971 PF06155.12 CDJ39007.1 - 1.4e-07 32.1 0.0 2.9e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) MipZ PF09140.11 CDJ39007.1 - 3.9e-06 26.3 0.0 8e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.6 CDJ39007.1 - 5.1e-06 26.5 0.1 2.7e-05 24.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 CDJ39007.1 - 0.0018 17.5 0.1 0.25 10.5 0.0 2.3 2 0 0 2 2 2 2 Anion-transporting ATPase VirC1 PF07015.11 CDJ39007.1 - 0.0025 17.1 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein CLP1_P PF16575.5 CDJ39007.1 - 0.047 13.5 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 CDJ39007.1 - 0.073 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase XPC-binding PF09280.11 CDJ39008.1 - 0.02 14.7 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 XPC-binding domain Ribosomal_L34 PF00468.17 CDJ39008.1 - 0.042 13.8 0.2 0.089 12.8 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein L34 Tox-REase-2 PF15646.6 CDJ39008.1 - 0.056 13.6 0.2 0.071 13.3 0.2 1.1 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 GldM_N PF12081.8 CDJ39008.1 - 0.063 13.4 0.5 0.11 12.5 0.1 1.5 2 0 0 2 2 2 0 GldM N-terminal domain BAR_2 PF10455.9 CDJ39008.1 - 0.077 12.1 0.4 0.083 12.0 0.4 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking CiPC PF15800.5 CDJ39011.1 - 0.42 10.3 2.3 0.25 11.0 0.2 1.6 2 0 0 2 2 2 0 Clock interacting protein circadian Voltage_CLC PF00654.20 CDJ39012.1 - 5.5e-67 226.5 35.2 5.1e-66 223.3 29.2 2.8 2 1 0 2 2 2 1 Voltage gated chloride channel zf-CCCH PF00642.24 CDJ39013.1 - 1.2e-09 37.8 12.2 8.4e-07 28.8 1.0 3.7 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ39013.1 - 2.7e-06 27.3 16.3 0.00041 20.3 1.1 3.5 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 CDJ39013.1 - 0.13 13.0 0.8 0.13 13.0 0.8 3.1 1 1 2 3 3 3 0 Torus domain zf-CCCH_4 PF18044.1 CDJ39013.1 - 0.47 10.3 16.8 0.37 10.6 1.1 4.0 3 2 0 3 3 3 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CDJ39013.1 - 0.59 10.7 11.3 7.6 7.2 1.3 3.7 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CDJ39013.1 - 0.69 10.1 8.6 2.5 8.3 3.9 2.3 1 1 1 2 2 2 0 Zinc-finger containing family TFIIA PF03153.13 CDJ39014.1 - 0.007 16.4 21.1 0.0089 16.1 21.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Menin PF05053.13 CDJ39014.1 - 0.24 9.7 5.2 0.32 9.3 5.2 1.0 1 0 0 1 1 1 0 Menin Exo_endo_phos PF03372.23 CDJ39015.1 - 0.00019 21.1 0.0 0.00053 19.6 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CDP-OH_P_transf PF01066.21 CDJ39016.1 - 3.2e-09 37.4 0.0 3.2e-09 37.4 0.0 3.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase RskA PF10099.9 CDJ39019.1 - 0.00096 19.5 4.3 0.0012 19.1 4.3 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Sterol-sensing PF12349.8 CDJ39020.1 - 8.6e-06 25.7 2.9 8.6e-06 25.7 2.9 1.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CDJ39020.1 - 0.0024 16.0 7.8 0.015 13.4 1.5 2.7 2 0 0 2 2 2 2 Patched family Ribo_biogen_C PF04034.13 CDJ39021.1 - 1.3e-34 118.6 0.0 2.3e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CDJ39021.1 - 1.5e-06 27.9 0.1 2.8e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Collagen PF01391.18 CDJ39022.1 - 0.16 11.7 16.0 0.059 13.1 12.5 2.0 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Ribosomal_L44 PF00935.19 CDJ39023.1 - 1.8e-35 121.2 11.8 2.4e-35 120.9 11.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 RESP18 PF14948.6 CDJ39025.1 - 0.069 13.5 0.0 0.086 13.1 0.0 1.2 1 0 0 1 1 1 0 RESP18 domain Kinesin PF00225.23 CDJ39027.1 - 1.7e-44 152.1 5.4 1.1e-43 149.5 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ39027.1 - 5.2e-16 58.9 0.3 4.2e-15 56.0 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding ATP_bind_3 PF01171.20 CDJ39027.1 - 2.1e-14 53.7 4.8 3.3e-07 30.2 0.1 3.8 2 2 1 3 3 2 2 PP-loop family zn-ribbon_14 PF16503.5 CDJ39027.1 - 7.5e-05 22.2 1.1 7.5e-05 22.2 1.1 2.9 3 0 0 3 3 2 1 Zinc-ribbon BUD22 PF09073.10 CDJ39027.1 - 0.0014 18.1 13.0 0.0029 17.0 13.0 1.4 1 0 0 1 1 1 1 BUD22 V_ATPase_I PF01496.19 CDJ39027.1 - 0.02 12.9 3.3 0.031 12.2 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MecA PF05389.12 CDJ39027.1 - 0.029 14.0 3.2 0.059 13.0 3.2 1.4 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) EIIBC-GUT_N PF03612.14 CDJ39027.1 - 0.03 14.1 6.0 0.079 12.7 6.0 1.7 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Connexin PF00029.19 CDJ39027.1 - 0.033 14.0 3.7 0.066 13.0 3.7 1.4 1 0 0 1 1 1 0 Connexin DUF2126 PF09899.9 CDJ39027.1 - 0.036 12.1 4.2 0.053 11.6 4.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PAPS_reduct PF01507.19 CDJ39027.1 - 0.043 13.8 1.0 0.17 11.9 1.0 2.1 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family LTV PF04180.14 CDJ39027.1 - 0.044 13.5 9.9 0.085 12.6 9.9 1.4 1 0 0 1 1 1 0 Low temperature viability protein SpoIIP PF07454.11 CDJ39027.1 - 0.49 9.8 11.0 0.94 8.9 11.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 CDJ39027.1 - 0.72 10.0 11.0 2 8.5 11.0 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SID-1_RNA_chan PF13965.6 CDJ39027.1 - 0.76 8.1 1.8 1.1 7.5 1.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF913 PF06025.12 CDJ39027.1 - 0.9 8.4 8.8 1.1 8.1 5.6 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SLC12 PF03522.15 CDJ39027.1 - 1.5 7.8 12.2 3 6.7 12.2 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Orf78 PF06024.12 CDJ39027.1 - 2.1 8.7 5.2 6.8 7.1 5.2 1.8 1 0 0 1 1 1 0 Orf78 (ac78) DUF4770 PF15994.5 CDJ39027.1 - 3 8.0 13.2 0.022 15.0 4.6 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4770) Peroxin-13_N PF04088.13 CDJ39027.1 - 3.1 8.1 5.5 11 6.3 5.5 1.9 1 0 0 1 1 1 0 Peroxin 13, N-terminal region RR_TM4-6 PF06459.12 CDJ39027.1 - 4.5 7.0 13.4 10 5.8 13.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MscS_TM PF12794.7 CDJ39027.1 - 5.4 5.8 6.6 19 4.0 6.6 1.9 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DnaJ-X PF14308.6 CDJ39027.1 - 5.7 6.3 12.6 0.73 9.2 7.9 1.7 2 0 0 2 2 2 0 X-domain of DnaJ-containing Serinc PF03348.15 CDJ39027.1 - 5.8 5.7 5.3 14 4.5 5.3 1.6 1 0 0 1 1 1 0 Serine incorporator (Serinc) CLN3 PF02487.17 CDJ39027.1 - 6.8 5.6 7.8 15 4.5 7.8 1.5 1 0 0 1 1 1 0 CLN3 protein Eapp_C PF10238.9 CDJ39027.1 - 6.9 6.7 19.1 5.7 7.0 13.5 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein VPS13_C PF16909.5 CDJ39028.1 - 4e-13 49.5 0.0 1.4e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 CDJ39028.1 - 0.0002 21.4 0.0 0.0002 21.4 0.0 4.1 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 GNAT_acetyltr_2 PF13718.6 CDJ39029.1 - 4e-82 275.0 0.0 2.8e-55 187.2 0.0 2.9 3 0 0 3 3 3 2 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CDJ39029.1 - 4.4e-43 147.7 0.0 4.4e-43 147.7 0.0 2.4 2 0 0 2 2 2 1 Possible tRNA binding domain Acetyltransf_1 PF00583.25 CDJ39029.1 - 0.00056 20.1 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF1598 PF07643.11 CDJ39029.1 - 0.0078 16.4 0.3 0.53 10.6 0.0 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1598) Acetyltransf_7 PF13508.7 CDJ39029.1 - 0.014 15.8 0.1 0.073 13.5 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SSF PF00474.17 CDJ39030.1 - 1.6e-14 53.6 19.8 4.4e-14 52.2 19.8 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family Tam41_Mmp37 PF09139.11 CDJ39031.1 - 1.2e-51 176.1 0.0 1.9e-51 175.4 0.0 1.3 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial ACBP PF00887.19 CDJ39032.1 - 1.5e-22 79.6 1.6 5.8e-22 77.7 1.6 2.1 1 0 0 1 1 1 1 Acyl CoA binding protein CbiC PF02570.15 CDJ39032.1 - 1.3 8.6 3.8 2.5 7.7 0.0 2.7 3 0 0 3 3 3 0 Precorrin-8X methylmutase MMR1 PF08505.10 CDJ39032.1 - 7.4 6.8 23.3 0.42 10.9 4.8 3.3 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein PEX-1N PF09262.11 CDJ39033.1 - 2.1e-15 56.9 0.0 5.2e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA PF00004.29 CDJ39034.1 - 3.6e-42 143.9 0.0 2.2e-36 125.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ39034.1 - 2e-09 37.1 0.0 0.003 17.3 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain IstB_IS21 PF01695.17 CDJ39034.1 - 1.5e-07 31.3 0.1 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 CDJ39034.1 - 6.3e-06 26.7 1.9 0.1 13.0 0.1 3.9 3 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CDJ39034.1 - 0.00012 22.4 0.1 0.39 11.0 0.1 3.5 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 CDJ39034.1 - 0.00024 21.5 0.0 0.32 11.4 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 CDJ39034.1 - 0.00079 19.6 0.0 0.0047 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDJ39034.1 - 0.0011 19.5 0.0 0.25 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CDJ39034.1 - 0.006 16.8 0.1 0.14 12.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 CDJ39034.1 - 0.011 15.7 0.4 0.23 11.5 0.1 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CDJ39034.1 - 0.013 16.0 0.0 3 8.3 0.0 2.4 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.16 CDJ39034.1 - 0.027 13.9 0.1 0.25 10.8 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 CDJ39034.1 - 0.049 13.2 0.2 0.84 9.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CDJ39034.1 - 0.063 13.0 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CDJ39034.1 - 0.064 13.2 0.3 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 CDJ39034.1 - 0.069 12.5 0.4 0.21 10.9 0.2 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CDJ39034.1 - 0.18 11.1 0.1 0.4 9.9 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin HalX PF08663.10 CDJ39035.1 - 0.1 12.9 2.4 3.8 7.9 0.0 2.6 2 0 0 2 2 2 0 HalX domain Arm PF00514.23 CDJ39036.1 - 2.6e-06 27.3 9.1 0.31 11.2 0.0 9.3 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CDJ39036.1 - 0.021 15.2 12.7 0.19 12.2 0.1 6.0 4 1 1 5 5 5 0 HEAT repeats Speriolin_C PF15059.6 CDJ39036.1 - 0.071 13.2 0.0 6.8 6.8 0.0 3.0 2 0 0 2 2 2 0 Speriolin C-terminus ThiF PF00899.21 CDJ39037.1 - 3.9e-46 157.4 0.1 5.7e-46 156.8 0.1 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CDJ39037.1 - 0.00012 22.3 0.1 0.47 10.7 0.0 2.5 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CDJ39037.1 - 0.0042 17.5 0.0 0.011 16.1 0.0 1.7 1 1 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 CDJ39037.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cpn10 PF00166.21 CDJ39038.1 - 1.5e-17 63.5 0.0 1.7e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit RPAP2_Rtr1 PF04181.13 CDJ39039.1 - 3.7e-08 33.6 2.0 3.7e-08 33.6 2.0 2.1 2 0 0 2 2 2 1 Rtr1/RPAP2 family TPH PF13868.6 CDJ39040.1 - 5.7e-45 153.4 143.6 5.7e-45 153.4 143.6 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain FapA PF03961.13 CDJ39041.1 - 4.4 5.8 11.5 6.4 5.3 11.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A AalphaY_MDB PF04611.12 CDJ39042.1 - 0.051 13.6 0.8 0.13 12.3 0.8 1.7 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Ank_2 PF12796.7 CDJ39043.1 - 8.5e-20 71.1 0.0 5.6e-10 39.7 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ39043.1 - 1.2e-18 67.3 0.1 2.1e-11 44.1 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ39043.1 - 4e-17 61.8 0.2 0.00033 21.0 0.0 5.7 5 1 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CDJ39043.1 - 4.4e-17 60.4 0.2 0.00075 19.8 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CDJ39043.1 - 6.2e-12 45.5 0.1 9.8e-06 25.8 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Sec7_N PF12783.7 CDJ39044.1 - 0.036 14.0 0.6 0.51 10.2 0.0 2.7 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal UPF0242 PF06785.11 CDJ39044.1 - 0.94 9.6 16.2 2.2 8.3 1.6 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_23 PF13476.6 CDJ39044.1 - 6.6 7.2 11.5 28 5.1 0.2 2.4 2 0 0 2 2 2 0 AAA domain Nrap_D4 PF17405.2 CDJ39045.1 - 1.2e-26 93.4 0.2 2.1e-26 92.6 0.2 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 CDJ39045.1 - 1.8e-17 63.6 0.3 2.3e-15 56.8 0.0 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 CDJ39045.1 - 1e-16 61.4 0.0 5.8e-16 59.0 0.0 2.3 3 0 0 3 3 3 1 Nrap protein domain 3 Nrap PF03813.14 CDJ39045.1 - 6.7e-16 58.7 0.0 2.2e-15 57.0 0.0 1.9 1 1 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 CDJ39045.1 - 1.6e-10 41.0 2.8 4.4e-09 36.3 0.5 3.5 3 1 0 3 3 3 1 Nrap protein PAP/OAS-like domain NIF PF03031.18 CDJ39047.1 - 2.5e-17 63.1 0.0 4.3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2057 PF09829.9 CDJ39047.1 - 0.12 12.5 5.7 2.7 8.1 5.7 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) CP12 PF02672.15 CDJ39049.1 - 0.1 13.3 0.7 0.1 13.3 0.7 3.6 4 1 0 4 4 4 0 CP12 domain FAD-oxidase_C PF02913.19 CDJ39049.1 - 7.4 6.1 7.7 0.81 9.3 0.2 2.5 3 0 0 3 3 3 0 FAD linked oxidases, C-terminal domain Ribosomal_60s PF00428.19 CDJ39050.1 - 0.013 16.1 0.7 0.027 15.1 0.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4680 PF15730.5 CDJ39050.1 - 0.053 13.9 1.7 0.057 13.8 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4680) Pex14_N PF04695.13 CDJ39051.1 - 0.095 13.3 12.1 1.2 9.8 5.8 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 CDJ39051.1 - 0.11 11.4 12.7 0.047 12.6 4.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ39051.1 - 0.17 11.5 20.6 0.51 9.9 13.3 2.2 2 0 0 2 2 2 0 Spt20 family Suf PF05843.14 CDJ39051.1 - 0.24 11.4 6.7 0.62 10.0 1.3 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RAB3GAP2_N PF14655.6 CDJ39051.1 - 0.3 10.3 5.9 1.1 8.5 1.5 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ca_hom_mod PF14798.6 CDJ39051.1 - 0.61 9.1 2.8 1.2 8.2 2.8 1.4 1 0 0 1 1 1 0 Calcium homeostasis modulator Roughex PF06020.11 CDJ39051.1 - 2.4 7.2 14.5 0.23 10.5 6.6 2.1 2 0 0 2 2 2 0 Drosophila roughex protein PSK_trans_fac PF07704.11 CDJ39051.1 - 3.5 8.4 8.4 0.46 11.3 2.4 2.5 3 0 0 3 3 3 0 Rv0623-like transcription factor YqzE PF14038.6 CDJ39051.1 - 4.3 7.4 5.2 20 5.3 0.6 2.4 2 0 0 2 2 2 0 YqzE-like protein DUF4680 PF15730.5 CDJ39052.1 - 0.083 13.2 0.8 0.083 13.2 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4680) SPATA3 PF15662.5 CDJ39054.1 - 3.5 8.2 12.7 1.4 9.5 1.1 2.7 3 0 0 3 3 3 0 Spermatogenesis-associated protein 3 family DUF4834 PF16118.5 CDJ39055.1 - 0.0019 19.1 1.3 0.0019 19.1 1.3 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4834) Folate_carrier PF01770.18 CDJ39055.1 - 0.026 13.3 1.1 0.044 12.5 1.1 1.3 1 0 0 1 1 1 0 Reduced folate carrier CSG2 PF16965.5 CDJ39055.1 - 0.072 12.0 2.6 0.05 12.6 1.3 1.4 1 1 0 1 1 1 0 Ceramide synthase regulator SID-1_RNA_chan PF13965.6 CDJ39055.1 - 0.17 10.3 0.4 0.2 10.0 0.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ39055.1 - 0.17 10.8 9.9 0.011 14.7 4.3 1.7 1 1 0 2 2 2 0 Serine incorporator (Serinc) Mitofilin PF09731.9 CDJ39055.1 - 0.43 9.4 27.7 0.66 8.7 27.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FHIPEP PF00771.20 CDJ39055.1 - 1.5 7.2 5.8 1 7.8 4.4 1.3 1 1 0 1 1 1 0 FHIPEP family DUF1980 PF09323.10 CDJ39055.1 - 1.6 8.6 3.6 0.57 10.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) G0-G1_switch_2 PF15103.6 CDJ39055.1 - 4.4 7.8 9.2 0.13 12.7 0.6 2.6 2 1 0 2 2 2 0 G0/G1 switch protein 2 SLC12 PF03522.15 CDJ39055.1 - 5.9 5.8 13.1 8.2 5.3 13.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF4647 PF15504.6 CDJ39055.1 - 5.9 5.9 15.5 10 5.1 15.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF966 PF06136.13 CDJ39055.1 - 6.1 6.4 22.4 10 5.7 22.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) EF-hand_6 PF13405.6 CDJ39058.1 - 0.00017 21.3 0.1 0.032 14.2 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CDJ39058.1 - 0.00018 20.8 0.1 0.028 14.0 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 CDJ39058.1 - 0.00027 21.3 0.1 0.054 14.0 0.0 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ39058.1 - 0.0039 16.6 0.5 0.14 11.7 0.0 2.5 2 0 0 2 2 2 1 EF hand SUIM_assoc PF16619.5 CDJ39059.1 - 0.06 13.4 7.3 0.13 12.4 7.3 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ39059.1 - 0.21 11.2 6.0 0.31 10.6 6.0 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ39059.1 - 1.1 8.1 5.0 1.9 7.4 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DnaJ_C PF01556.18 CDJ39060.1 - 4.5e-44 150.1 0.3 6.5e-44 149.6 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDJ39060.1 - 2.3e-25 88.5 4.0 4.1e-25 87.7 4.0 1.4 1 0 0 1 1 1 1 DnaJ domain TPT PF03151.16 CDJ39061.1 - 1.4e-07 31.2 7.3 2.6e-07 30.3 7.3 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 CDJ39061.1 - 9.9e-07 28.3 5.1 9.9e-07 28.3 5.1 1.9 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 CDJ39061.1 - 3.9e-05 23.0 0.8 5.8e-05 22.4 0.8 1.5 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CDJ39061.1 - 0.00022 21.4 19.8 0.00027 21.1 4.3 3.6 3 1 1 4 4 4 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CDJ39061.1 - 0.0015 17.8 2.3 0.0029 16.8 2.3 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 CDJ39061.1 - 0.0029 16.6 0.4 0.004 16.2 0.4 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Herpes_UL79 PF03049.14 CDJ39061.1 - 0.049 13.3 0.1 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 UL79 family AP2 PF00847.20 CDJ39062.1 - 0.019 15.2 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 AP2 domain DUF1980 PF09323.10 CDJ39063.1 - 1.3 8.9 0.0 1.3 8.9 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF1980) PAS_4 PF08448.10 CDJ39063.1 - 2.1 8.7 9.6 0.7 10.2 0.8 3.7 1 1 2 4 4 4 0 PAS fold PAP_assoc PF03828.19 CDJ39065.1 - 4.3e-09 36.4 0.7 9.4e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CDJ39065.1 - 0.00019 21.7 0.0 0.0027 18.0 0.0 2.3 2 0 0 2 2 2 1 Nucleotidyltransferase domain TetR_C_33 PF13305.6 CDJ39065.1 - 4.8 8.0 10.6 0.12 13.1 0.5 3.4 4 1 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Patched PF02460.18 CDJ39066.1 - 1.4e-104 350.9 5.3 8.3e-55 186.3 0.0 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CDJ39066.1 - 1.4e-30 106.2 6.6 1.4e-30 106.2 6.6 2.6 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation DUF1090 PF06476.12 CDJ39067.1 - 0.051 13.7 3.4 0.12 12.5 3.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) HEM4 PF02602.15 CDJ39069.1 - 0.046 13.1 0.2 0.069 12.5 0.2 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD ESX-1_EspG PF14011.6 CDJ39069.1 - 0.068 12.8 0.1 0.099 12.2 0.1 1.2 1 0 0 1 1 1 0 EspG family CRAL_TRIO_2 PF13716.6 CDJ39070.1 - 0.0094 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CDJ39070.1 - 0.013 15.3 0.0 0.036 13.8 0.0 1.8 1 1 0 1 1 1 0 CRAL/TRIO domain HAGH_C PF16123.5 CDJ39071.1 - 1.2e-29 102.7 0.1 1.8e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CDJ39071.1 - 3.3e-08 33.8 0.8 4.9e-08 33.2 0.3 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily UPF0139 PF03669.13 CDJ39072.1 - 1.6e-07 31.1 0.1 2.1e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Mito_carr PF00153.27 CDJ39074.1 - 6.5e-35 118.9 0.1 1.8e-17 63.0 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.27 CDJ39075.1 - 2e-18 66.1 0.0 2.2e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein zf-CCCH PF00642.24 CDJ39078.1 - 4.1e-09 36.1 16.4 0.00011 22.1 0.8 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CDJ39078.1 - 1.7e-05 25.5 13.9 0.042 14.5 0.0 3.4 1 1 2 3 3 3 3 Torus domain zf-CCCH_3 PF15663.5 CDJ39078.1 - 2.6e-05 24.4 10.2 0.0054 16.9 3.0 2.4 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 CDJ39078.1 - 0.0041 16.9 22.7 0.045 13.6 5.7 3.9 3 1 0 3 3 3 2 CCCH-type zinc finger zf-C3H1 PF10650.9 CDJ39078.1 - 0.0043 16.8 4.3 0.12 12.2 1.7 2.5 2 0 0 2 2 2 1 Putative zinc-finger domain zf-CCCH_2 PF14608.6 CDJ39078.1 - 0.022 15.2 0.9 0.022 15.2 0.9 3.5 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 CDJ39078.1 - 0.18 11.9 25.8 0.6 10.2 3.6 4.2 3 1 0 3 3 3 0 Zinc finger domain DUF1664 PF07889.12 CDJ39079.1 - 0.002 18.2 5.0 0.002 18.2 5.0 10.3 6 2 4 10 10 10 4 Protein of unknown function (DUF1664) KELK PF15796.5 CDJ39079.1 - 0.011 16.1 6.2 0.011 16.1 6.2 14.1 4 3 5 12 12 12 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TAT_signal PF10518.9 CDJ39080.1 - 0.021 14.6 8.6 0.1 12.5 8.6 2.3 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence KELK PF15796.5 CDJ39080.1 - 2.3 8.7 12.0 2.8 8.4 4.4 2.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase PF00069.25 CDJ39081.1 - 2.9e-49 167.8 0.0 6.3e-36 124.1 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ39081.1 - 2e-22 79.7 0.0 2.5e-20 72.9 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ39081.1 - 5e-13 47.6 0.7 0.016 14.7 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ39081.1 - 2.1e-12 47.3 0.0 6.6e-05 23.3 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ39081.1 - 9.9e-10 37.6 3.5 0.0078 16.1 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CDJ39081.1 - 4.5e-07 29.6 3.3 0.27 11.1 0.3 4.4 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ39081.1 - 2.5e-06 26.7 8.7 2.3 7.9 0.0 5.2 5 0 0 5 5 5 4 EF hand Kinase-like PF14531.6 CDJ39081.1 - 0.0035 16.7 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Presenilin PF01080.17 CDJ39081.1 - 1.6 7.4 23.8 1.2 7.8 0.9 2.4 2 0 0 2 2 2 0 Presenilin CSG2 PF16965.5 CDJ39081.1 - 2 7.3 5.2 6.3 5.6 1.7 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator Bromodomain PF00439.25 CDJ39082.1 - 2.2e-15 56.5 0.0 4.6e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain SET PF00856.28 CDJ39082.1 - 3.8e-15 56.7 0.0 3.8e-15 56.7 0.0 9.2 6 3 0 6 6 6 1 SET domain PHD PF00628.29 CDJ39082.1 - 2.9e-05 23.9 1.3 2.9e-05 23.9 1.3 9.7 9 2 1 10 10 10 5 PHD-finger FYRN PF05964.14 CDJ39082.1 - 0.0052 16.6 0.0 0.019 14.8 0.0 2.0 1 0 0 1 1 1 1 F/Y-rich N-terminus ABC_tran PF00005.27 CDJ39083.1 - 3.8e-11 43.7 2.4 7.1e-11 42.8 2.4 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 CDJ39083.1 - 9.3e-05 22.1 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 CDJ39083.1 - 0.0002 21.2 0.4 0.00035 20.4 0.4 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 CDJ39083.1 - 0.00024 21.1 0.3 0.00038 20.4 0.3 1.4 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 CDJ39083.1 - 0.00067 19.6 3.3 0.0023 17.9 3.2 2.1 1 1 0 1 1 1 1 NACHT domain AAA_21 PF13304.6 CDJ39083.1 - 0.00097 19.0 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 CDJ39083.1 - 0.0019 18.4 0.3 0.0037 17.5 0.3 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SMC_N PF02463.19 CDJ39083.1 - 0.002 17.6 0.1 0.0029 17.1 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDJ39083.1 - 0.0028 18.2 0.6 0.0028 18.2 0.6 2.6 1 1 1 2 2 1 1 AAA domain AAA_25 PF13481.6 CDJ39083.1 - 0.0029 17.2 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CDJ39083.1 - 0.0086 15.8 0.6 0.0086 15.8 0.6 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CDJ39083.1 - 0.009 16.0 0.5 0.077 13.0 0.4 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.27 CDJ39083.1 - 0.0097 15.5 0.6 0.018 14.6 0.3 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CDJ39083.1 - 0.017 15.5 6.9 0.017 15.5 6.9 1.7 1 1 1 2 2 2 0 AAA ATPase domain CobN-Mg_chel PF02514.16 CDJ39083.1 - 0.02 12.6 5.2 0.022 12.5 5.2 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase TsaE PF02367.17 CDJ39083.1 - 0.023 14.7 0.2 0.043 13.8 0.2 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 CDJ39083.1 - 0.044 13.4 0.0 0.094 12.3 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 CDJ39083.1 - 0.055 12.9 0.1 0.09 12.2 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA PF00004.29 CDJ39083.1 - 0.06 13.8 1.3 0.15 12.4 1.3 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDJ39083.1 - 0.069 12.7 0.4 0.13 11.8 0.4 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 CDJ39083.1 - 0.098 12.7 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pyr_redox PF00070.27 CDJ39083.1 - 0.15 12.6 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RNA_helicase PF00910.22 CDJ39083.1 - 0.19 12.2 0.1 0.36 11.2 0.1 1.6 1 1 0 1 1 1 0 RNA helicase Septin PF00735.18 CDJ39083.1 - 0.2 10.9 1.4 0.24 10.6 0.6 1.5 1 1 0 1 1 1 0 Septin Pyr_redox_2 PF07992.14 CDJ39083.1 - 0.2 10.8 2.7 0.2 10.9 0.3 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA_33 PF13671.6 CDJ39083.1 - 0.21 11.7 5.2 0.7 10.0 5.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDJ39083.1 - 0.46 10.8 5.7 0.43 10.8 4.3 1.8 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 CDJ39083.1 - 0.53 9.4 4.9 0.69 9.0 4.9 1.2 1 0 0 1 1 1 0 G-protein alpha subunit RR_TM4-6 PF06459.12 CDJ39083.1 - 0.88 9.3 12.1 1.2 8.9 12.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DAO PF01266.24 CDJ39083.1 - 1 8.8 5.6 1.6 8.3 5.6 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase ResIII PF04851.15 CDJ39083.1 - 1.6 8.7 8.0 4.1 7.4 7.8 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit FapA PF03961.13 CDJ39083.1 - 1.8 7.1 7.3 2.3 6.7 7.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prefoldin_2 PF01920.20 CDJ39084.1 - 2.5e-19 69.2 2.7 2.5e-19 69.2 2.7 1.7 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin PF02996.17 CDJ39084.1 - 6.3e-05 22.9 0.9 0.13 12.2 0.1 2.2 2 0 0 2 2 2 2 Prefoldin subunit DUF1043 PF06295.12 CDJ39084.1 - 0.0018 18.3 1.9 0.0018 18.3 1.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1043) Helo_like_N PF17111.5 CDJ39084.1 - 0.0049 16.3 6.5 0.013 14.9 0.5 2.1 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins Filament PF00038.21 CDJ39084.1 - 0.0069 16.0 5.2 0.034 13.7 0.5 2.1 2 0 0 2 2 2 1 Intermediate filament protein Spc24 PF08286.11 CDJ39084.1 - 0.014 15.6 5.0 0.91 9.8 1.3 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 LytTR PF04397.15 CDJ39084.1 - 0.025 14.8 0.5 0.7 10.2 0.1 2.1 1 1 1 2 2 2 0 LytTr DNA-binding domain DUF615 PF04751.14 CDJ39084.1 - 0.027 14.5 5.3 0.038 14.0 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF615) DUF1319 PF07028.11 CDJ39084.1 - 0.028 14.6 1.7 0.058 13.6 0.1 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1319) DASH_Dad3 PF08656.10 CDJ39084.1 - 0.031 14.3 1.0 1.5 8.9 0.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4407 PF14362.6 CDJ39084.1 - 0.042 13.2 7.7 0.09 12.1 7.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MscS_porin PF12795.7 CDJ39084.1 - 0.043 13.4 0.9 0.043 13.4 0.9 2.6 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain CLZ PF16526.5 CDJ39084.1 - 0.044 14.1 2.1 8.2 6.9 0.3 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_DNA_bd PF12329.8 CDJ39084.1 - 0.076 13.0 6.2 0.33 11.0 0.8 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3138 PF11336.8 CDJ39084.1 - 0.19 10.3 6.4 0.27 9.8 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) KfrA_N PF11740.8 CDJ39084.1 - 0.21 12.3 13.6 0.15 12.7 2.0 3.0 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term COG2 PF06148.11 CDJ39084.1 - 0.23 11.6 4.7 0.13 12.3 1.0 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CdvA PF18822.1 CDJ39084.1 - 0.31 10.9 5.1 0.87 9.4 0.5 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Fib_alpha PF08702.10 CDJ39084.1 - 0.32 11.2 4.0 0.95 9.6 0.8 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GrpE PF01025.19 CDJ39084.1 - 0.33 10.6 4.9 2.1 8.0 1.4 2.1 2 0 0 2 2 2 0 GrpE DUF1664 PF07889.12 CDJ39084.1 - 0.34 11.0 4.9 0.24 11.4 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4618 PF15397.6 CDJ39084.1 - 0.44 9.9 6.7 1.2 8.5 6.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) APG6_N PF17675.1 CDJ39084.1 - 0.46 11.0 16.4 8.7 6.9 16.0 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region HSCB_C PF07743.13 CDJ39084.1 - 0.48 11.0 6.1 1 9.9 0.9 2.4 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain TMPIT PF07851.13 CDJ39084.1 - 0.48 9.6 2.8 0.91 8.7 2.8 1.4 1 1 0 1 1 1 0 TMPIT-like protein DUF5320 PF17253.2 CDJ39084.1 - 0.73 10.9 4.0 8.3 7.5 0.2 2.5 2 1 1 3 3 2 0 Family of unknown function (DUF5320) NAM-associated PF14303.6 CDJ39084.1 - 0.95 10.2 5.5 4.8 7.9 5.5 1.9 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain CASP_C PF08172.12 CDJ39084.1 - 1.5 8.1 9.7 2.8 7.2 1.4 2.1 2 0 0 2 2 2 0 CASP C terminal DUF4140 PF13600.6 CDJ39084.1 - 1.6 9.2 10.6 2.3 8.7 1.3 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) AATF-Che1 PF13339.6 CDJ39084.1 - 2 9.1 8.3 5.5 7.7 3.0 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF4600 PF15372.6 CDJ39084.1 - 2.3 8.7 8.3 1.7 9.1 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Seryl_tRNA_N PF02403.22 CDJ39084.1 - 4.2 7.6 8.9 7.7 6.8 0.7 2.5 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain XhlA PF10779.9 CDJ39084.1 - 5.9 7.2 10.2 4.5 7.5 0.1 2.5 3 0 0 3 3 2 0 Haemolysin XhlA Phage_GP20 PF06810.11 CDJ39084.1 - 6.9 6.5 10.9 0.35 10.6 1.3 2.6 2 1 1 3 3 3 0 Phage minor structural protein GP20 DivIC PF04977.15 CDJ39084.1 - 7.1 6.5 13.7 2.4 8.0 2.0 3.0 3 0 0 3 3 3 0 Septum formation initiator MS_channel PF00924.18 CDJ39085.1 - 5.1e-12 45.8 1.7 9.4e-12 44.9 1.7 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel CPP1-like PF11833.8 CDJ39086.1 - 2.3 7.8 8.2 0.81 9.3 5.4 1.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2207 PF09972.9 CDJ39086.1 - 8.4 5.0 8.3 17 4.0 8.4 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) CPL PF08144.11 CDJ39087.1 - 0.084 13.2 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 CPL (NUC119) domain SelB-wing_2 PF09106.11 CDJ39087.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.5 3 0 0 3 3 3 0 Elongation factor SelB, winged helix DUF3446 PF11928.8 CDJ39087.1 - 0.14 12.5 7.9 0.043 14.1 3.0 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain LexA_DNA_bind PF01726.16 CDJ39087.1 - 1.2 8.9 3.5 0.81 9.5 0.1 2.5 3 0 0 3 3 3 0 LexA DNA binding domain UDPGP PF01704.18 CDJ39088.1 - 2.6e-23 82.4 0.0 1.7e-20 73.1 0.0 2.4 2 1 0 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase DUF2722 PF10846.8 CDJ39088.1 - 0.0007 18.7 0.9 0.0007 18.7 0.9 2.4 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Tsg PF04668.12 CDJ39088.1 - 0.037 14.7 1.1 0.037 14.7 1.1 1.8 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region AAA_assoc_2 PF16193.5 CDJ39088.1 - 0.17 12.2 0.7 0.57 10.6 0.7 1.9 1 0 0 1 1 1 0 AAA C-terminal domain Mak16 PF04874.14 CDJ39088.1 - 4.3 8.0 8.2 0.75 10.4 4.3 1.7 2 0 0 2 2 2 0 Mak16 protein C-terminal region RRM_1 PF00076.22 CDJ39089.1 - 0.00016 21.4 0.0 0.00046 20.0 0.0 1.7 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 CDJ39089.1 - 0.00074 19.4 0.1 0.0044 16.9 0.0 2.0 1 1 1 2 2 2 1 RL domain RRM_7 PF16367.5 CDJ39089.1 - 0.03 14.4 0.0 0.21 11.7 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif DUF1744 PF08490.12 CDJ39091.1 - 2.2e-14 52.9 0.1 2.2e-14 52.9 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) TFIIA PF03153.13 CDJ39091.1 - 0.00029 20.9 18.4 0.00029 20.9 18.4 3.8 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit KduI PF04962.12 CDJ39091.1 - 0.13 11.6 0.8 0.27 10.5 0.8 1.5 1 0 0 1 1 1 0 KduI/IolB family DUF572 PF04502.13 CDJ39091.1 - 0.46 10.1 27.4 1.4 8.5 6.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) Peptidase_S64 PF08192.11 CDJ39091.1 - 4.3 5.7 34.8 0.22 10.0 12.2 2.6 3 0 0 3 3 3 0 Peptidase family S64 LAP1C PF05609.12 CDJ39091.1 - 5.7 5.9 32.6 0.57 9.2 11.0 2.6 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) EI24 PF07264.11 CDJ39091.1 - 8.3 6.6 16.1 21 5.3 16.1 1.7 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DNA_pol_B_exo1 PF03104.19 CDJ39092.1 - 8.5e-39 133.6 0.0 1.8e-38 132.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CDJ39092.1 - 2e-09 36.7 0.3 1.6e-06 27.1 0.3 3.2 3 0 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CDJ39092.1 - 2e-07 30.9 0.0 2.4e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CDJ39092.1 - 0.0011 18.9 0.0 0.0033 17.4 0.0 1.8 1 1 0 1 1 1 1 RNase_H superfamily TEX15 PF15326.6 CDJ39092.1 - 0.012 15.3 2.8 0.022 14.5 2.8 1.3 1 0 0 1 1 1 0 Testis expressed sequence 15 MFS_5 PF05631.14 CDJ39094.1 - 8.7e-06 24.9 0.1 1e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM HemY_N PF07219.13 CDJ39094.1 - 0.0071 16.5 1.7 0.0071 16.5 1.7 1.7 2 0 0 2 2 2 1 HemY protein N-terminus G0-G1_switch_2 PF15103.6 CDJ39094.1 - 0.016 15.6 1.5 0.023 15.1 1.5 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 MFS_1 PF07690.16 CDJ39094.1 - 0.017 14.1 9.5 0.022 13.7 9.5 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Ctr PF04145.15 CDJ39094.1 - 0.99 10.0 3.5 0.95 10.1 0.4 2.0 2 0 0 2 2 2 0 Ctr copper transporter family TFIIA PF03153.13 CDJ39094.1 - 4.7 7.1 16.6 5.7 6.8 16.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EMC3_TMCO1 PF01956.16 CDJ39094.1 - 9.2 6.0 7.5 0.88 9.3 2.9 1.6 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like CAP_C PF08603.11 CDJ39095.1 - 4.3e-50 169.4 2.3 4.7e-50 169.3 2.3 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 CDJ39095.1 - 0.00011 22.0 5.0 0.00015 21.5 5.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF918 PF06033.11 CDJ39095.1 - 0.00018 21.5 0.3 0.0013 18.8 0.1 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF918) TT_ORF2a PF08197.11 CDJ39095.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 pORF2a truncated protein FKBP_C PF00254.28 CDJ39097.1 - 1.6e-22 79.6 0.0 2.3e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Shisa PF13908.6 CDJ39097.1 - 0.097 12.9 0.3 0.14 12.4 0.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Glucan_synthase PF02364.15 CDJ39099.1 - 1.9e-92 310.9 12.0 6.9e-58 196.5 10.8 4.2 2 2 1 4 4 4 4 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CDJ39099.1 - 3.1e-12 47.0 5.0 6.1e-10 39.5 5.0 2.5 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Ribonuclease_P PF00825.18 CDJ39099.1 - 0.022 14.8 0.0 0.049 13.7 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease P Hemagglutinin PF00509.18 CDJ39100.1 - 0.0059 15.1 0.0 0.0093 14.4 0.0 1.2 1 0 0 1 1 1 1 Haemagglutinin Rep_3 PF01051.21 CDJ39101.1 - 0.088 12.6 1.9 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Initiator Replication protein Peptidase_C12 PF01088.21 CDJ39102.1 - 0.12 12.1 0.1 1.3 8.7 0.0 2.2 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF2528 PF10800.8 CDJ39104.1 - 0.11 13.1 0.1 1.4 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2528) SUIM_assoc PF16619.5 CDJ39104.1 - 1.5 8.9 8.7 3.9 7.6 8.7 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF755 PF05501.11 CDJ39105.1 - 6.1 7.2 11.4 5.8 7.2 9.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ39107.1 - 0.00084 19.0 6.0 0.00084 19.0 6.0 3.7 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Pex14_N PF04695.13 CDJ39107.1 - 0.0054 17.4 16.3 0.0054 17.4 16.3 4.6 3 1 1 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region BAF1_ABF1 PF04684.13 CDJ39107.1 - 0.037 13.1 17.4 0.064 12.3 2.8 2.4 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Allantoicase PF03561.15 CDJ39107.1 - 0.13 12.3 6.8 1.4 8.9 1.4 2.6 2 0 0 2 2 2 0 Allantoicase repeat DSHCT PF08148.12 CDJ39107.1 - 0.93 9.1 12.0 1.9 8.1 0.0 3.9 4 0 0 4 4 4 0 DSHCT (NUC185) domain FHIPEP PF00771.20 CDJ39107.1 - 2.1 6.7 12.3 0.27 9.7 4.8 2.3 2 0 0 2 2 2 0 FHIPEP family Hid1 PF12722.7 CDJ39107.1 - 8.6 4.3 30.6 2.4 6.2 9.4 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Hid1 PF12722.7 CDJ39109.1 - 0.013 13.7 12.8 0.014 13.6 12.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 CDJ39109.1 - 0.019 14.0 14.5 0.022 13.8 14.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 YL1 PF05764.13 CDJ39109.1 - 0.023 14.8 22.3 0.028 14.6 22.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SOG2 PF10428.9 CDJ39109.1 - 0.04 13.1 18.7 0.046 12.9 18.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Miga PF10265.9 CDJ39109.1 - 0.069 12.1 9.2 0.071 12.1 9.2 1.0 1 0 0 1 1 1 0 Mitoguardin Presenilin PF01080.17 CDJ39109.1 - 0.074 11.8 21.7 0.097 11.4 21.7 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ39109.1 - 0.11 12.5 10.9 0.17 11.9 10.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Macoilin PF09726.9 CDJ39109.1 - 0.11 11.0 12.8 0.13 10.8 12.8 1.0 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 CDJ39109.1 - 0.18 10.5 20.8 0.2 10.3 20.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PNISR PF15996.5 CDJ39109.1 - 0.26 11.5 22.9 0.31 11.3 22.9 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR FAM220 PF15487.6 CDJ39109.1 - 0.31 10.6 13.5 0.37 10.4 13.5 1.1 1 0 0 1 1 1 0 FAM220 family O-antigen_lig PF13425.6 CDJ39109.1 - 0.69 8.6 2.9 0.85 8.3 2.9 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Apt1 PF10351.9 CDJ39109.1 - 0.81 8.5 11.7 0.96 8.2 11.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 CDJ39109.1 - 0.86 8.8 9.8 1 8.5 9.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4551 PF15087.6 CDJ39109.1 - 1.4 7.6 16.7 1.7 7.4 16.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Sin_N PF04801.13 CDJ39109.1 - 1.5 8.0 26.2 1.8 7.7 26.2 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region PAT1 PF09770.9 CDJ39109.1 - 1.5 7.0 33.9 1.8 6.8 33.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ39109.1 - 1.7 8.6 16.3 2.3 8.2 16.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S64 PF08192.11 CDJ39109.1 - 1.8 7.0 14.5 2.1 6.7 14.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Membralin PF09746.9 CDJ39109.1 - 4.5 6.2 9.5 6.4 5.7 9.5 1.3 1 0 0 1 1 1 0 Tumour-associated protein CDK2AP PF09806.9 CDJ39109.1 - 4.8 7.2 26.8 7.1 6.6 26.8 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein ALMT PF11744.8 CDJ39109.1 - 5.6 5.7 14.6 7.3 5.3 14.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SAPS PF04499.15 CDJ39109.1 - 6 5.5 14.4 7.6 5.2 14.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Plasmodium_Vir PF05795.11 CDJ39109.1 - 7.3 5.9 13.7 9.7 5.5 13.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hid1 PF12722.7 CDJ39110.1 - 5.3 5.1 7.2 5.8 4.9 7.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Membralin PF09746.9 CDJ39111.1 - 2.3 7.2 8.1 2 7.4 8.1 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF5624 PF18538.1 CDJ39111.1 - 4.3 7.4 9.2 7 6.8 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) LptF_LptG PF03739.14 CDJ39111.1 - 7.2 5.4 6.8 7.6 5.3 6.8 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Glyco_transf_41 PF13844.6 CDJ39111.1 - 8.7 4.7 9.7 10 4.4 9.7 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 Pkinase_Tyr PF07714.17 CDJ39113.1 - 3e-07 30.0 0.0 4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ39113.1 - 0.0033 16.8 0.1 0.0061 16.0 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Ndc1_Nup PF09531.10 CDJ39113.1 - 0.032 13.0 0.5 0.035 12.8 0.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NPR3 PF03666.13 CDJ39113.1 - 0.032 13.0 0.9 0.039 12.7 0.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ACC_central PF08326.12 CDJ39113.1 - 0.032 12.4 0.4 0.04 12.1 0.4 1.0 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region DUF3915 PF13054.6 CDJ39113.1 - 0.033 14.2 1.4 0.07 13.1 1.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) Suf PF05843.14 CDJ39113.1 - 0.054 13.5 2.0 0.063 13.3 2.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4366 PF14283.6 CDJ39113.1 - 0.068 13.2 4.4 0.13 12.3 4.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 CDJ39113.1 - 0.15 10.8 4.0 0.18 10.5 4.0 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_60s PF00428.19 CDJ39113.1 - 0.16 12.6 15.0 0.25 11.9 15.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1180 PF06679.12 CDJ39113.1 - 0.19 12.2 4.9 0.29 11.5 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Fusion_gly PF00523.18 CDJ39113.1 - 0.45 8.7 4.3 0.57 8.4 4.3 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Neur_chan_memb PF02932.16 CDJ39113.1 - 0.5 10.4 1.9 0.6 10.1 1.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region THOC2_N PF16134.5 CDJ39113.1 - 0.57 8.7 3.0 0.69 8.5 3.0 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Spore_coat_CotO PF14153.6 CDJ39113.1 - 0.63 9.9 9.5 0.84 9.5 9.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SprA-related PF12118.8 CDJ39113.1 - 0.65 9.1 17.4 0.85 8.7 17.4 1.1 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.13 CDJ39113.1 - 0.78 9.7 11.1 1 9.3 11.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CTU2 PF10288.9 CDJ39113.1 - 0.95 9.7 6.2 1.3 9.3 6.2 1.2 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF612 PF04747.12 CDJ39113.1 - 1 8.4 15.2 1.3 8.1 15.2 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF612 BAF1_ABF1 PF04684.13 CDJ39113.1 - 1.2 8.1 6.7 1.6 7.7 6.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RskA PF10099.9 CDJ39113.1 - 1.7 8.9 20.1 2.2 8.5 20.1 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Kei1 PF08552.11 CDJ39113.1 - 1.7 8.5 4.6 2.3 8.0 4.6 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ribosomal_60s PF00428.19 CDJ39117.1 - 0.38 11.4 10.3 0.51 10.9 10.3 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein IMS PF00817.20 CDJ39118.1 - 0.00072 19.6 0.4 0.00085 19.3 0.4 1.2 1 0 0 1 1 1 1 impB/mucB/samB family Presenilin PF01080.17 CDJ39118.1 - 0.0041 15.9 5.0 0.0049 15.7 5.0 1.3 1 0 0 1 1 1 1 Presenilin SpoIIP PF07454.11 CDJ39118.1 - 0.0046 16.5 2.8 0.0046 16.5 2.8 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) BAF1_ABF1 PF04684.13 CDJ39118.1 - 0.0048 16.0 3.4 0.0054 15.9 3.4 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Tim54 PF11711.8 CDJ39118.1 - 0.0081 15.0 2.9 0.0085 14.9 2.9 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 CDJ39118.1 - 0.039 13.0 2.6 0.035 13.2 2.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DDHD PF02862.17 CDJ39118.1 - 0.041 14.0 2.8 0.045 13.9 2.8 1.2 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.9 CDJ39118.1 - 0.13 10.6 16.6 0.12 10.6 16.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Eapp_C PF10238.9 CDJ39118.1 - 0.48 10.5 11.0 0.85 9.7 11.0 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein Plasmodium_Vir PF05795.11 CDJ39118.1 - 0.56 9.6 2.8 0.59 9.5 2.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ndc1_Nup PF09531.10 CDJ39118.1 - 0.63 8.7 4.9 0.64 8.6 4.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex14_N PF04695.13 CDJ39118.1 - 0.96 10.1 17.2 0.15 12.7 13.5 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NPR3 PF03666.13 CDJ39118.1 - 2.5 6.8 8.6 3.5 6.3 8.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 CDJ39118.1 - 2.6 6.2 7.2 3.2 5.9 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 CDJ39118.1 - 3.8 7.6 14.2 5.6 7.0 14.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) NARP1 PF12569.8 CDJ39118.1 - 8.2 5.2 16.3 11 4.8 16.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 UPF0560 PF10577.9 CDJ39118.1 - 8.3 4.8 20.8 10 4.5 20.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 EOS1 PF12326.8 CDJ39118.1 - 8.4 6.3 5.6 33 4.4 5.9 1.7 2 0 0 2 2 2 0 N-glycosylation protein MDM10 PF12519.8 CDJ39118.1 - 9 5.0 7.7 11 4.8 7.7 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Ripply PF14998.6 CDJ39119.1 - 0.02 15.5 0.1 0.031 14.9 0.1 1.2 1 0 0 1 1 1 0 Transcription Regulator Spt20 PF12090.8 CDJ39121.1 - 0.0047 16.6 19.9 0.035 13.7 6.4 2.4 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 CDJ39121.1 - 0.0055 15.7 13.5 0.28 10.1 7.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ39121.1 - 0.04 13.9 18.7 0.14 12.1 7.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ANAPC_CDC26 PF10471.9 CDJ39121.1 - 0.048 14.5 20.8 0.21 12.5 5.8 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 TMEM247 PF15444.6 CDJ39121.1 - 0.53 10.3 2.9 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 247 PGA2 PF07543.12 CDJ39121.1 - 1.1 9.3 6.4 2.3 8.2 0.3 2.7 3 0 0 3 3 3 0 Protein trafficking PGA2 DUF4834 PF16118.5 CDJ39121.1 - 2.1 9.3 8.7 6.2 7.9 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Med3 PF11593.8 CDJ39121.1 - 2.3 7.3 17.8 0.71 9.0 5.9 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal MAP65_ASE1 PF03999.12 CDJ39121.1 - 7.8 5.1 10.2 1.6 7.3 4.4 2.0 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Activator_LAG-3 PF11498.8 CDJ39121.1 - 8 5.3 25.4 5.2 5.9 4.2 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 ATP-synt_F PF01990.17 CDJ39123.1 - 2.4e-27 95.1 0.0 2.8e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF5423 PF17461.2 CDJ39125.1 - 0.74 8.6 3.1 14 4.4 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5423) DUF4131 PF13567.6 CDJ39125.1 - 1.3 8.7 4.6 3 7.5 4.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3824 PF12868.7 CDJ39126.1 - 0.023 15.3 5.3 0.055 14.1 5.3 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Miga PF10265.9 CDJ39126.1 - 0.28 10.1 3.6 0.4 9.6 3.6 1.1 1 0 0 1 1 1 0 Mitoguardin Ribosomal_60s PF00428.19 CDJ39126.1 - 0.48 11.0 5.5 0.31 11.7 1.2 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF1127 PF06568.11 CDJ39126.1 - 5.8 6.7 7.9 12 5.7 7.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) Ku PF02735.16 CDJ39127.1 - 4.4e-09 36.3 1.0 1.1e-07 31.8 0.1 2.4 1 1 0 2 2 2 1 Ku70/Ku80 beta-barrel domain FHIPEP PF00771.20 CDJ39127.1 - 0.0017 16.9 1.0 0.0018 16.8 1.0 1.0 1 0 0 1 1 1 1 FHIPEP family Med15 PF09606.10 CDJ39127.1 - 0.0019 17.0 10.2 0.0019 17.0 10.2 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Androgen_recep PF02166.16 CDJ39127.1 - 0.0032 16.4 10.6 0.0033 16.3 10.6 1.1 1 0 0 1 1 1 1 Androgen receptor DUF3818 PF12825.7 CDJ39127.1 - 0.0035 16.4 3.5 0.0042 16.2 3.5 1.0 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) SprA-related PF12118.8 CDJ39127.1 - 0.006 15.8 12.0 0.0068 15.6 12.0 1.1 1 0 0 1 1 1 1 SprA-related family TFIIA PF03153.13 CDJ39127.1 - 0.01 15.9 10.3 0.01 15.8 10.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex26 PF07163.12 CDJ39127.1 - 0.013 14.8 3.0 0.015 14.7 3.0 1.1 1 0 0 1 1 1 0 Pex26 protein RskA PF10099.9 CDJ39127.1 - 0.019 15.3 5.6 0.024 14.9 5.6 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ39127.1 - 0.032 15.2 1.9 0.044 14.7 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MHC_I PF00129.18 CDJ39127.1 - 0.033 13.8 3.3 0.043 13.4 3.3 1.1 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 DUF4770 PF15994.5 CDJ39127.1 - 0.037 14.3 5.3 0.045 14.0 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF3391 PF11871.8 CDJ39127.1 - 0.041 14.4 6.7 0.052 14.1 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF2722 PF10846.8 CDJ39127.1 - 0.069 12.1 14.4 0.084 11.8 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2368 PF10166.9 CDJ39127.1 - 0.15 11.7 6.5 0.22 11.1 6.5 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) ABC2_membrane_3 PF12698.7 CDJ39127.1 - 0.31 10.1 2.2 0.36 9.9 2.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein 7tm_7 PF08395.12 CDJ39127.1 - 0.33 10.1 2.2 0.42 9.8 2.2 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Presenilin PF01080.17 CDJ39127.1 - 0.34 9.6 2.5 0.36 9.5 2.5 1.1 1 0 0 1 1 1 0 Presenilin GTA_holin_3TM PF11351.8 CDJ39127.1 - 0.58 10.7 5.0 0.81 10.2 5.0 1.4 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release LPP20 PF02169.16 CDJ39127.1 - 0.63 10.4 10.7 0.96 9.8 10.7 1.3 1 0 0 1 1 1 0 LPP20 lipoprotein Spt20 PF12090.8 CDJ39127.1 - 0.98 9.0 19.7 1.2 8.6 19.7 1.1 1 0 0 1 1 1 0 Spt20 family Maf1 PF09174.10 CDJ39127.1 - 1.1 9.4 4.6 1.4 9.0 4.6 1.1 1 0 0 1 1 1 0 Maf1 regulator Activator_LAG-3 PF11498.8 CDJ39127.1 - 2.7 6.9 22.7 3.1 6.7 22.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 NTP_transf_5 PF14907.6 CDJ39127.1 - 3.3 7.2 6.8 4.4 6.8 6.8 1.1 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase TFIIA PF03153.13 CDJ39131.1 - 0.032 14.3 12.8 0.039 13.9 12.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ39131.1 - 0.059 13.0 13.9 0.081 12.5 13.9 1.1 1 0 0 1 1 1 0 Spt20 family DUF908 PF06012.12 CDJ39131.1 - 0.13 11.7 2.6 0.13 11.7 2.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PAT1 PF09770.9 CDJ39131.1 - 0.35 9.1 8.5 0.41 8.9 8.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 CDJ39131.1 - 2.4 6.8 4.2 2.8 6.6 4.2 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ39131.1 - 2.7 9.0 5.2 4.3 8.3 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) UPF0560 PF10577.9 CDJ39131.1 - 4.7 5.6 9.6 5.9 5.3 9.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3123 PF11321.8 CDJ39131.1 - 6.6 7.4 6.8 2.2 9.0 3.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3123) Connexin PF00029.19 CDJ39132.1 - 3.6 7.3 23.8 0.76 9.5 5.6 2.2 2 0 0 2 2 2 0 Connexin Med19 PF10278.9 CDJ39132.1 - 4.3 7.2 25.5 2.1 8.3 7.8 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF1772 PF08592.11 CDJ39132.1 - 4.7 7.5 11.3 0.41 10.9 1.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) PseudoU_synth_1 PF01416.20 CDJ39134.1 - 0.00071 20.0 6.9 0.17 12.3 5.7 3.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase CrgA PF06781.12 CDJ39134.1 - 0.21 11.7 0.2 0.21 11.7 0.2 5.5 5 1 1 6 6 6 0 Cell division protein CrgA DUF979 PF06166.12 CDJ39134.1 - 2.4 7.3 3.1 3.7 6.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF979) SR-25 PF10500.9 CDJ39135.1 - 0.0078 15.8 5.2 0.0078 15.8 5.2 5.2 3 1 2 5 5 5 2 Nuclear RNA-splicing-associated protein FAP PF07174.11 CDJ39136.1 - 4.9 6.5 21.5 6 6.2 21.5 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Rtf2 PF04641.12 CDJ39136.1 - 7.1 5.9 8.2 7.3 5.9 8.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2052 PF09747.9 CDJ39141.1 - 0.69 10.0 32.7 0.76 9.9 32.7 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 CDJ39141.1 - 0.75 8.0 28.6 0.82 7.9 28.6 1.0 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 CDJ39141.1 - 1.4 9.2 28.3 2 8.7 28.3 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SRP-alpha_N PF04086.13 CDJ39141.1 - 2 8.3 28.0 2.1 8.2 28.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RR_TM4-6 PF06459.12 CDJ39141.1 - 2.6 7.8 32.6 2.8 7.7 32.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CDJ39141.1 - 3.3 6.6 16.9 3.8 6.4 16.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) eIF-3_zeta PF05091.12 CDJ39141.1 - 3.3 6.6 35.3 4.2 6.2 35.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Merozoite_SPAM PF07133.11 CDJ39141.1 - 4.3 7.3 21.7 5.8 6.9 21.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CLN3 PF02487.17 CDJ39141.1 - 5.1 6.0 21.0 6.3 5.7 21.0 1.2 1 0 0 1 1 1 0 CLN3 protein NPR3 PF03666.13 CDJ39141.1 - 5.5 5.7 28.8 5.9 5.6 28.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Gti1_Pac2 PF09729.9 CDJ39141.1 - 5.8 7.0 23.6 7.4 6.6 23.6 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family CCSAP PF15748.5 CDJ39141.1 - 8.9 6.4 37.9 10 6.2 37.9 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF2370 PF10176.9 CDJ39141.1 - 9.3 5.8 13.6 12 5.5 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF4045 PF13254.6 CDJ39141.1 - 9.9 5.7 27.8 11 5.6 27.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ank_2 PF12796.7 CDJ39142.1 - 8.4e-21 74.4 0.0 3.6e-10 40.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ39142.1 - 7e-19 67.9 2.9 6.6e-09 36.1 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ39142.1 - 7.6e-17 61.2 0.3 1.9e-07 31.2 0.0 2.6 2 2 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ39142.1 - 2.8e-15 54.9 0.1 0.00056 20.1 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 CDJ39142.1 - 5.4e-14 51.9 0.0 0.0022 18.4 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Toxin_30 PF08117.11 CDJ39142.1 - 0.1 12.9 0.1 78 3.6 0.0 3.7 4 0 0 4 4 4 0 Ptu family DUF1151 PF06625.11 CDJ39143.1 - 0.011 15.6 9.6 0.011 15.6 9.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1151) GT87 PF09594.10 CDJ39143.1 - 0.14 11.9 4.6 0.75 9.5 1.7 2.3 2 0 0 2 2 2 0 Glycosyltransferase family 87 PEHE PF15275.6 CDJ39143.1 - 5.7 7.6 15.8 1.5 9.5 0.5 3.2 3 0 0 3 3 3 0 PEHE domain tRNA-synt_2b PF00587.25 CDJ39145.1 - 5.8e-14 52.4 0.1 8.9e-13 48.6 0.1 2.4 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) SUIM_assoc PF16619.5 CDJ39145.1 - 5.3 7.2 13.2 0.34 11.0 4.6 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 2OG-FeII_Oxy_2 PF13532.6 CDJ39146.1 - 1.6e-12 48.0 0.2 2.4e-12 47.4 0.2 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_1 PF00561.20 CDJ39146.1 - 0.018 14.7 1.3 0.021 14.5 1.3 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2722 PF10846.8 CDJ39146.1 - 0.023 13.6 12.2 0.04 12.9 12.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ39146.1 - 0.038 14.0 25.1 0.048 13.7 25.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PDEase_I_N PF08499.12 CDJ39146.1 - 0.45 10.4 2.7 0.87 9.5 2.7 1.5 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Spt20 PF12090.8 CDJ39146.1 - 0.7 9.5 23.5 1.1 8.8 23.5 1.3 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ39146.1 - 6.3 7.8 10.1 2.4 9.2 7.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DivIC PF04977.15 CDJ39146.1 - 6.9 6.5 14.0 14 5.5 14.0 1.5 1 0 0 1 1 1 0 Septum formation initiator RskA PF10099.9 CDJ39146.1 - 7.7 6.8 38.9 0.68 10.2 28.0 2.4 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF4366 PF14283.6 CDJ39147.1 - 3.4 7.7 4.6 4.8 7.2 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SUIM_assoc PF16619.5 CDJ39148.1 - 0.0085 16.1 3.2 0.0085 16.1 3.2 2.3 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 MDFI PF15316.6 CDJ39148.1 - 0.9 9.6 8.1 0.59 10.2 4.8 2.0 2 0 0 2 2 2 0 MyoD family inhibitor DUF4834 PF16118.5 CDJ39148.1 - 2.9 8.9 5.6 7.9 7.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ39148.1 - 3.3 7.2 19.1 0.17 11.5 4.7 2.1 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 CDJ39148.1 - 3.7 7.5 24.8 5 7.0 24.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ39148.1 - 8.8 6.6 46.9 0.21 11.9 27.8 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ39148.1 - 9.2 5.8 14.0 2.2 7.9 9.5 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sof1 PF04158.14 CDJ39149.1 - 4.9e-31 106.8 11.0 5.4e-30 103.5 9.7 2.3 2 0 0 2 2 2 1 Sof1-like domain WD40 PF00400.32 CDJ39149.1 - 6.3e-15 55.3 7.5 0.0052 17.6 0.2 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 CDJ39149.1 - 0.00052 20.0 0.0 0.0045 16.9 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CDJ39149.1 - 0.0022 18.3 0.0 1.6 9.1 0.0 3.6 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2956 PF11169.8 CDJ39150.1 - 0.0068 16.6 0.3 0.033 14.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2956) Spt20 PF12090.8 CDJ39150.1 - 0.29 10.7 9.6 0.26 10.8 2.4 2.2 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 CDJ39150.1 - 2.5 8.0 17.3 10 6.0 17.3 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pinin_SDK_memA PF04696.13 CDJ39151.1 - 0.84 9.7 37.3 2.5 8.2 5.7 3.9 4 0 0 4 4 4 0 pinin/SDK/memA/ protein conserved region Spt20 PF12090.8 CDJ39151.1 - 0.98 9.0 61.4 0.099 12.2 16.6 4.0 4 0 0 4 4 4 0 Spt20 family eIF-3_zeta PF05091.12 CDJ39151.1 - 1.3 7.9 26.0 1.5 7.7 3.0 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BORG_CEP PF14957.6 CDJ39151.1 - 5.2 8.2 16.3 65 4.7 0.1 3.4 3 0 0 3 3 3 0 Cdc42 effector DUF572 PF04502.13 CDJ39153.1 - 0.39 10.3 12.6 0.63 9.6 12.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) SR-25 PF10500.9 CDJ39154.1 - 0.29 10.7 1.4 0.35 10.4 1.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med3 PF11593.8 CDJ39154.1 - 2.9 7.0 7.5 3.2 6.8 7.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1467 PF07330.12 CDJ39155.1 - 0.3 11.0 0.5 0.46 10.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) ABC_tran PF00005.27 CDJ39156.1 - 1.2e-11 45.3 0.0 1.4e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 CDJ39156.1 - 0.00027 20.6 0.2 0.00051 19.7 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 CDJ39156.1 - 0.00077 18.2 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CDJ39156.1 - 0.0027 17.6 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 CDJ39156.1 - 0.016 15.7 0.7 0.033 14.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 CDJ39156.1 - 0.017 14.6 0.1 0.026 14.0 0.1 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Ribosomal_60s PF00428.19 CDJ39156.1 - 0.017 15.7 4.0 0.017 15.7 4.0 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein AAA_21 PF13304.6 CDJ39156.1 - 0.019 14.8 0.1 0.026 14.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system GHMP_kinases_N PF00288.26 CDJ39156.1 - 0.022 15.0 2.5 3.9 7.8 0.7 2.4 2 0 0 2 2 2 0 GHMP kinases N terminal domain FtsK_SpoIIIE PF01580.18 CDJ39156.1 - 0.035 13.4 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 CDJ39156.1 - 0.036 14.2 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 CDJ39156.1 - 0.044 13.4 0.1 0.54 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDJ39156.1 - 0.056 14.0 0.4 0.34 11.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CDJ39156.1 - 0.078 13.1 0.2 0.15 12.2 0.2 1.6 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 CDJ39156.1 - 0.099 12.7 0.1 0.18 11.9 0.0 1.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_15 PF13175.6 CDJ39156.1 - 0.12 12.0 0.4 0.18 11.5 0.4 1.2 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 CDJ39156.1 - 0.15 11.9 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_27 PF13514.6 CDJ39156.1 - 0.2 11.2 0.1 0.2 11.2 0.1 1.6 2 0 0 2 2 2 0 AAA domain LRR_9 PF14580.6 CDJ39157.1 - 6.6e-16 58.3 0.1 2.1e-15 56.7 0.1 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CDJ39157.1 - 4.8e-07 30.0 8.7 0.00065 20.0 0.6 3.5 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ39157.1 - 1.4e-06 28.0 6.9 0.0065 16.2 0.5 3.1 2 1 0 2 2 2 2 Leucine rich repeat Chorein_N PF12624.7 CDJ39158.1 - 1.1e-20 73.9 0.0 1.4e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 COX1 PF00115.20 CDJ39159.1 - 0.0068 15.3 0.1 0.01 14.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3169 PF11368.8 CDJ39159.1 - 0.13 11.7 0.5 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) AA_permease_2 PF13520.6 CDJ39159.1 - 0.18 10.6 2.9 0.28 10.0 2.9 1.2 1 0 0 1 1 1 0 Amino acid permease Secretin_N_2 PF07655.13 CDJ39159.1 - 2.9 8.5 9.2 0.53 10.9 3.0 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain EIF4E-T PF10477.9 CDJ39159.1 - 6.1 5.5 35.2 9.1 5.0 35.2 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E SPX PF03105.19 CDJ39160.1 - 0.077 12.9 20.4 0.1 12.5 20.4 1.1 1 0 0 1 1 1 0 SPX domain Hid1 PF12722.7 CDJ39160.1 - 0.13 10.4 4.9 0.14 10.2 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MAP65_ASE1 PF03999.12 CDJ39160.1 - 0.31 9.7 10.0 0.33 9.6 10.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Plasmodium_Vir PF05795.11 CDJ39160.1 - 0.36 10.2 8.6 0.55 9.6 8.6 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PNISR PF15996.5 CDJ39160.1 - 0.8 10.0 16.1 0.085 13.1 11.7 1.5 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Peptidase_S64 PF08192.11 CDJ39160.1 - 2.6 6.4 16.7 3 6.2 16.7 1.2 1 0 0 1 1 1 0 Peptidase family S64 Cwf_Cwc_15 PF04889.12 CDJ39160.1 - 2.9 7.5 10.2 0.25 11.1 4.4 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GREB1 PF15782.5 CDJ39160.1 - 9.2 3.2 13.3 9.6 3.2 13.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glt_symporter PF03616.14 CDJ39161.1 - 0.00061 18.6 0.3 0.0011 17.8 0.3 1.3 1 0 0 1 1 1 1 Sodium/glutamate symporter Menin PF05053.13 CDJ39161.1 - 0.00091 17.7 5.1 0.0012 17.3 5.1 1.2 1 0 0 1 1 1 1 Menin TraT PF05818.12 CDJ39161.1 - 0.0064 16.2 5.2 0.0096 15.6 5.2 1.2 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein CD20 PF04103.15 CDJ39161.1 - 0.0065 16.6 1.6 0.023 14.8 1.5 1.9 1 1 0 1 1 1 1 CD20-like family Bac_luciferase PF00296.20 CDJ39161.1 - 0.012 15.1 3.7 0.021 14.3 3.7 1.4 1 0 0 1 1 1 0 Luciferase-like monooxygenase RAB3GAP2_N PF14655.6 CDJ39161.1 - 0.014 14.7 5.5 0.021 14.1 5.5 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF5349 PF17298.2 CDJ39161.1 - 0.18 11.5 9.3 0.36 10.6 9.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Peptidase_S15 PF02129.18 CDJ39161.1 - 0.28 10.7 5.5 0.35 10.4 5.5 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Roughex PF06020.11 CDJ39161.1 - 1.5 7.9 7.0 2 7.4 7.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein R_equi_Vir PF05526.11 CDJ39161.1 - 2.2 8.1 4.7 3 7.7 4.7 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Spt20 PF12090.8 CDJ39161.1 - 4.9 6.7 29.9 0.057 13.0 19.3 2.1 2 0 0 2 2 2 0 Spt20 family Tim17 PF02466.19 CDJ39162.1 - 2.4e-11 44.0 5.3 3.4e-11 43.5 5.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Rick_17kDa_Anti PF05433.15 CDJ39162.1 - 2.4 8.1 16.2 2.1 8.3 4.1 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain Ribosomal_60s PF00428.19 CDJ39163.1 - 0.17 12.5 5.1 0.23 12.1 5.1 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Metal_resist PF13801.6 CDJ39164.1 - 0.0039 17.4 1.1 0.0039 17.4 1.1 3.6 4 1 0 4 4 4 1 Heavy-metal resistance PLDc_2 PF13091.6 CDJ39165.1 - 2.1e-20 72.9 0.0 6.8e-08 32.5 0.0 3.8 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 CDJ39165.1 - 1.4e-10 40.9 0.1 4.1e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Pex19 PF04614.12 CDJ39165.1 - 0.054 13.3 0.2 0.054 13.3 0.2 2.5 2 1 0 2 2 2 0 Pex19 protein family TFIIA PF03153.13 CDJ39165.1 - 0.13 12.2 27.1 0.85 9.6 1.5 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ39165.1 - 0.18 10.7 12.8 0.11 11.4 1.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ39165.1 - 0.38 9.4 5.6 0.95 8.1 0.1 2.2 2 0 0 2 2 2 0 Presenilin SR-25 PF10500.9 CDJ39165.1 - 1.3 8.6 16.7 0.033 13.8 9.8 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Suf PF05843.14 CDJ39165.1 - 2.4 8.0 11.9 0.25 11.3 3.5 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ39166.1 - 0.27 11.2 14.5 0.33 10.9 14.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tuberin PF03542.16 CDJ39166.1 - 0.4 9.7 1.4 0.53 9.3 1.0 1.3 1 1 0 1 1 1 0 Tuberin Kei1 PF08552.11 CDJ39168.1 - 0.29 11.0 8.4 0.36 10.7 8.4 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4366 PF14283.6 CDJ39168.1 - 0.52 10.4 6.0 0.59 10.2 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Baculo_PP31 PF05311.11 CDJ39168.1 - 0.65 9.4 14.1 0.82 9.1 14.1 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) AIF_C PF14721.6 CDJ39168.1 - 0.67 10.3 7.0 0.93 9.9 7.0 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pex14_N PF04695.13 CDJ39168.1 - 0.69 10.6 19.0 0.78 10.4 19.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.14 CDJ39168.1 - 0.94 7.7 13.9 1 7.6 13.9 1.0 1 0 0 1 1 1 0 CDC45-like protein CCDC53 PF10152.9 CDJ39168.1 - 0.94 9.9 15.8 1.1 9.7 15.8 1.0 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Dicty_REP PF05086.12 CDJ39168.1 - 1.4 6.8 14.8 1.5 6.7 14.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Protocadherin PF08374.11 CDJ39168.1 - 1.5 8.8 9.9 1.8 8.5 9.9 1.1 1 0 0 1 1 1 0 Protocadherin Rtf2 PF04641.12 CDJ39168.1 - 1.5 8.1 15.5 1.6 8.0 15.5 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2072 PF09845.9 CDJ39168.1 - 2.4 8.4 9.0 2.8 8.2 9.0 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein Methyltransf_32 PF13679.6 CDJ39168.1 - 2.4 8.1 11.0 3 7.8 11.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain SpoIIP PF07454.11 CDJ39168.1 - 2.6 7.4 15.4 3.1 7.2 15.4 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 CDJ39168.1 - 2.7 8.1 11.6 3.2 7.9 11.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal BORG_CEP PF14957.6 CDJ39168.1 - 3 9.0 11.3 3.3 8.9 11.3 1.1 1 0 0 1 1 1 0 Cdc42 effector RR_TM4-6 PF06459.12 CDJ39168.1 - 3.2 7.5 16.0 3.4 7.4 16.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ39168.1 - 3.4 7.6 13.4 3.6 7.5 13.4 1.0 1 0 0 1 1 1 0 Protein Family FAM60A MDM31_MDM32 PF08118.11 CDJ39168.1 - 4.1 6.0 10.3 4.1 5.9 10.3 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF913 PF06025.12 CDJ39168.1 - 4.6 6.1 9.3 5 6.0 9.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Asp-B-Hydro_N PF05279.11 CDJ39168.1 - 4.8 7.2 11.9 5.4 7.0 11.9 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Endostatin PF06482.11 CDJ39168.1 - 4.9 6.5 13.8 5.6 6.3 13.8 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Med19 PF10278.9 CDJ39168.1 - 5.2 7.0 16.8 5.7 6.8 16.8 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Neur_chan_memb PF02932.16 CDJ39168.1 - 5.3 7.0 14.2 5.8 6.9 14.2 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ39168.1 - 5.5 5.6 18.0 5.7 5.6 18.0 1.0 1 0 0 1 1 1 0 Presenilin Consortin_C PF15281.6 CDJ39168.1 - 5.8 6.9 7.9 20 5.2 7.9 1.8 1 1 0 1 1 1 0 Consortin C-terminus Zip PF02535.22 CDJ39168.1 - 6 6.0 6.7 6.6 5.8 6.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0565 PF10561.9 CDJ39168.1 - 6.1 6.0 8.7 6.1 6.0 8.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 V_ATPase_I PF01496.19 CDJ39168.1 - 6.2 4.6 13.8 6.7 4.5 13.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hydin_ADK PF17213.3 CDJ39168.1 - 7.2 6.8 12.3 7.8 6.7 12.3 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Suf PF05843.14 CDJ39168.1 - 7.6 6.4 19.5 9.4 6.1 19.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4746 PF15928.5 CDJ39168.1 - 8 5.8 12.7 8.8 5.6 12.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Folliculin PF11704.8 CDJ39168.1 - 9.5 6.1 13.0 11 5.8 13.0 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Connexin PF00029.19 CDJ39168.1 - 9.9 5.8 10.8 11 5.7 10.8 1.1 1 0 0 1 1 1 0 Connexin DEAD PF00270.29 CDJ39169.1 - 1.7e-10 40.9 0.0 2.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase UPF0016 PF01169.19 CDJ39170.1 - 5.1e-12 46.0 11.4 8.7e-12 45.2 11.4 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0016 DUF2722 PF10846.8 CDJ39170.1 - 6.9e-05 22.0 0.3 7.5e-05 21.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ39170.1 - 0.0076 16.9 4.1 0.013 16.2 4.1 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ctr PF04145.15 CDJ39170.1 - 0.059 14.0 0.2 0.093 13.3 0.2 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Suf PF05843.14 CDJ39170.1 - 0.085 12.8 2.5 0.11 12.5 2.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) OATP PF03137.20 CDJ39170.1 - 0.17 10.1 0.0 0.23 9.7 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TFIIA PF03153.13 CDJ39170.1 - 0.2 11.6 11.4 0.27 11.2 11.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EIIBC-GUT_N PF03612.14 CDJ39170.1 - 0.23 11.2 2.3 0.45 10.2 2.3 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus UPF0560 PF10577.9 CDJ39170.1 - 0.3 9.5 5.8 0.42 9.0 5.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3464 PF11947.8 CDJ39170.1 - 4.1 7.1 5.1 9.2 6.0 5.1 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Spt20 PF12090.8 CDJ39170.1 - 5.8 6.5 20.5 8.3 5.9 20.5 1.1 1 0 0 1 1 1 0 Spt20 family Coilin_N PF15862.5 CDJ39170.1 - 9 6.1 8.8 14 5.5 8.8 1.2 1 0 0 1 1 1 0 Coilin N-terminus DUF4834 PF16118.5 CDJ39170.1 - 9.3 7.3 6.5 16 6.5 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SEA PF01390.20 CDJ39171.1 - 0.065 13.3 0.4 0.065 13.3 0.4 2.5 2 2 0 2 2 2 0 SEA domain PEP-utilisers_N PF05524.13 CDJ39171.1 - 3.8 7.7 12.9 0.59 10.3 8.9 1.6 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Serinc PF03348.15 CDJ39171.1 - 5.6 5.8 6.2 9 5.1 6.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) PAT1 PF09770.9 CDJ39171.1 - 7.4 4.7 38.1 8.4 4.5 38.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dehydrin PF00257.19 CDJ39172.1 - 0.55 10.8 11.0 0.5 10.9 7.9 2.1 2 0 0 2 2 2 0 Dehydrin DUF1180 PF06679.12 CDJ39172.1 - 2.5 8.5 14.4 4.1 7.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) DUF702 PF05142.12 CDJ39173.1 - 0.39 11.2 6.6 0.58 10.6 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF3275 PF11679.8 CDJ39173.1 - 9.4 6.2 8.2 11 6.0 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) ProQ PF04352.13 CDJ39174.1 - 0.0043 16.9 2.8 0.0061 16.4 2.8 1.3 1 0 0 1 1 1 1 ProQ/FINO family Med3 PF11593.8 CDJ39174.1 - 0.0047 16.2 20.1 0.0053 16.0 20.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ39174.1 - 0.0087 16.4 11.9 0.011 16.1 11.9 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ39174.1 - 2 8.4 15.6 2.3 8.2 15.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CTP_transf_1 PF01148.20 CDJ39175.1 - 1.5e-50 172.5 29.0 1.5e-49 169.2 29.0 2.3 1 1 0 1 1 1 1 Cytidylyltransferase family FlaC_arch PF05377.11 CDJ39175.1 - 0.65 10.4 2.0 1.5 9.3 2.0 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Trehalase PF01204.18 CDJ39175.1 - 2 7.2 6.5 3 6.6 6.5 1.2 1 0 0 1 1 1 0 Trehalase TFIIA PF03153.13 CDJ39175.1 - 7.3 6.5 48.8 8.9 6.2 38.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RCC1 PF00415.18 CDJ39176.1 - 1.4e-15 57.6 3.2 1.6e-08 35.0 0.1 4.4 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ39176.1 - 5.2e-13 48.4 14.9 0.00018 21.2 0.3 3.3 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat adh_short PF00106.25 CDJ39178.1 - 2.2e-08 33.8 0.7 4.2e-08 32.9 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ39178.1 - 4.2e-05 23.2 0.1 6.1e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PDEase_I PF00233.19 CDJ39179.1 - 8.6e-38 130.4 6.4 1.1e-37 130.0 6.4 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CDJ39179.1 - 0.072 13.3 0.7 0.22 11.7 0.1 1.9 1 1 1 2 2 2 0 HD domain MAGI_u5 PF16666.5 CDJ39179.1 - 3.7 7.7 6.1 6.4 7.0 6.1 1.4 1 0 0 1 1 1 0 Unstructured region on MAGI RRM_1 PF00076.22 CDJ39181.1 - 2.6e-26 91.2 0.1 4.5e-15 55.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FANCI_S1-cap PF14674.6 CDJ39181.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 1 cap Presenilin PF01080.17 CDJ39181.1 - 2 7.1 5.0 2.8 6.6 5.0 1.2 1 0 0 1 1 1 0 Presenilin IPK PF03770.16 CDJ39182.1 - 0.0047 16.8 0.0 1.4 8.7 0.0 2.1 1 1 1 2 2 2 2 Inositol polyphosphate kinase TUDOR PF00567.24 CDJ39182.1 - 0.077 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Tudor domain CtnDOT_TraJ PF07863.11 CDJ39182.1 - 0.47 11.1 2.6 0.67 10.6 2.6 1.3 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon Ribosomal_60s PF00428.19 CDJ39182.1 - 4.5 7.9 14.9 6.8 7.4 14.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein V-ATPase_G_2 PF16999.5 CDJ39184.1 - 0.0012 19.3 1.7 0.0012 19.2 1.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Androgen_recep PF02166.16 CDJ39184.1 - 1.7 7.4 6.4 1.5 7.6 6.4 1.0 1 0 0 1 1 1 0 Androgen receptor RskA PF10099.9 CDJ39185.1 - 0.00023 21.5 6.1 0.00023 21.5 6.1 2.5 2 1 0 2 2 2 1 Anti-sigma-K factor rskA Hamartin PF04388.12 CDJ39185.1 - 0.027 13.2 15.0 0.041 12.6 15.0 1.3 1 0 0 1 1 1 0 Hamartin protein MFAP1 PF06991.11 CDJ39185.1 - 1.1 9.0 6.6 0.13 12.1 0.9 2.1 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing TRAUB PF08164.12 CDJ39186.1 - 1.5e-13 51.1 0.0 1.8e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal SR-25 PF10500.9 CDJ39187.1 - 0.28 10.8 4.1 0.34 10.5 4.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Citrate_synt PF00285.21 CDJ39188.1 - 0.99 8.4 8.8 0.75 8.8 0.8 2.3 2 0 0 2 2 2 0 Citrate synthase, C-terminal domain DUF3446 PF11928.8 CDJ39188.1 - 3.7 7.9 19.1 5.2 7.4 9.3 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF3138 PF11336.8 CDJ39188.1 - 4 5.9 11.4 5.3 5.5 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ATG16 PF08614.11 CDJ39189.1 - 0.00074 19.8 6.3 0.00074 19.8 6.3 2.8 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 CDJ39189.1 - 0.0016 19.0 9.8 0.0016 19.0 9.8 2.1 2 0 0 2 2 2 1 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 CDJ39189.1 - 0.0041 17.3 7.8 0.0041 17.3 7.8 2.0 2 0 0 2 2 2 1 Tropomyosin like HAP1_N PF04849.13 CDJ39189.1 - 0.005 16.1 7.8 0.0081 15.4 7.8 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region HOOK PF05622.12 CDJ39189.1 - 0.0057 14.9 5.1 0.0057 14.9 5.1 1.5 2 0 0 2 2 2 1 HOOK protein Csm1_N PF18504.1 CDJ39189.1 - 0.0063 16.8 11.0 0.022 15.1 0.9 2.9 3 0 0 3 3 3 1 Csm1 N-terminal domain Filament PF00038.21 CDJ39189.1 - 0.0067 16.1 6.5 0.0067 16.1 6.5 1.7 2 0 0 2 2 2 1 Intermediate filament protein HMMR_N PF15905.5 CDJ39189.1 - 0.0081 15.7 5.9 0.0081 15.7 5.9 1.7 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal Lectin_N PF03954.14 CDJ39189.1 - 0.0085 15.8 5.9 0.18 11.5 3.0 2.4 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain Phlebovirus_NSM PF07246.11 CDJ39189.1 - 0.018 14.4 2.4 0.028 13.8 2.4 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M HAUS-augmin3 PF14932.6 CDJ39189.1 - 0.081 12.5 11.9 0.033 13.8 6.9 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Jnk-SapK_ap_N PF09744.9 CDJ39189.1 - 0.1 12.8 13.4 0.083 13.1 7.6 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FAM76 PF16046.5 CDJ39189.1 - 0.13 11.6 7.8 0.22 10.9 6.3 1.8 2 0 0 2 2 2 0 FAM76 protein ADIP PF11559.8 CDJ39189.1 - 0.16 12.1 16.0 0.052 13.6 11.7 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 CDJ39189.1 - 0.17 10.7 12.2 0.067 12.1 9.0 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein CtIP_N PF10482.9 CDJ39189.1 - 0.25 11.4 10.6 0.14 12.2 6.2 2.3 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain V_ATPase_I PF01496.19 CDJ39189.1 - 0.26 9.1 2.5 0.29 9.0 2.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 CDJ39189.1 - 0.32 11.0 13.6 0.12 12.4 1.3 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Mod_r PF07200.13 CDJ39189.1 - 0.4 10.8 12.8 0.48 10.5 8.1 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.6 CDJ39189.1 - 0.46 9.8 12.4 0.15 11.4 8.4 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 CDJ39189.1 - 0.46 10.6 7.7 26 5.0 7.7 2.9 1 1 0 1 1 1 0 bZIP transcription factor GIT_CC PF16559.5 CDJ39189.1 - 0.47 10.4 10.0 2.6 8.0 3.0 2.6 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor PRKG1_interact PF15898.5 CDJ39189.1 - 0.6 11.0 11.5 0.34 11.8 8.1 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TMF_TATA_bd PF12325.8 CDJ39189.1 - 1.2 9.4 10.9 1.6 9.0 7.8 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 CDJ39189.1 - 1.3 9.1 10.5 1.4 9.0 8.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Sec34 PF04136.15 CDJ39189.1 - 1.4 8.8 9.0 0.42 10.5 6.2 1.5 2 0 0 2 2 1 0 Sec34-like family FapA PF03961.13 CDJ39189.1 - 1.6 7.3 6.5 0.47 9.0 3.8 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A Phage_GP20 PF06810.11 CDJ39189.1 - 1.8 8.4 11.4 0.48 10.2 6.8 2.3 2 1 0 2 2 2 0 Phage minor structural protein GP20 Pedibin PF08182.11 CDJ39189.1 - 2.2 8.1 6.5 0.26 11.1 1.0 2.2 2 0 0 2 2 2 0 Pedibin/Hym-346 family Seryl_tRNA_N PF02403.22 CDJ39189.1 - 2.2 8.5 11.3 18 5.6 9.4 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 CDJ39189.1 - 2.4 8.3 9.1 1.4 9.1 6.7 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 CDJ39189.1 - 2.7 8.5 11.5 2.1 8.8 8.8 2.1 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF4094 PF13334.6 CDJ39189.1 - 3.2 8.2 6.8 1.3 9.5 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Uso1_p115_C PF04871.13 CDJ39189.1 - 3.5 8.0 13.1 1.8 9.0 9.8 2.1 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 CDJ39189.1 - 5.6 7.0 7.4 6.5 6.8 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 CDJ39189.1 - 5.7 7.6 9.4 6.3 7.5 6.8 2.4 2 1 0 2 2 2 0 Initiation control protein YabA UPF0449 PF15136.6 CDJ39189.1 - 8 7.0 11.0 68 4.0 8.7 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Ribosomal_60s PF00428.19 CDJ39190.1 - 0.17 12.5 60.4 1.3 9.6 4.4 5.6 4 1 1 5 5 5 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ39191.1 - 0.0035 17.7 14.9 0.0035 17.7 14.9 2.9 2 1 0 2 2 2 1 Anti-sigma-K factor rskA IMUP PF15761.5 CDJ39191.1 - 0.29 11.8 5.2 0.62 10.8 5.2 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Enterotoxin_a PF01375.17 CDJ39191.1 - 0.66 9.5 6.8 0.96 9.0 6.8 1.2 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain AAA_23 PF13476.6 CDJ39191.1 - 3.6 8.1 15.9 0.22 12.0 9.4 2.0 2 0 0 2 2 2 0 AAA domain Presenilin PF01080.17 CDJ39191.1 - 3.8 6.2 7.8 6.7 5.4 7.8 1.5 1 0 0 1 1 1 0 Presenilin Exonuc_VII_L PF02601.15 CDJ39191.1 - 6.9 6.1 17.4 3.5 7.1 13.7 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit FHIPEP PF00771.20 CDJ39192.1 - 0.032 12.7 5.7 0.038 12.5 5.7 1.0 1 0 0 1 1 1 0 FHIPEP family EIF4E-T PF10477.9 CDJ39192.1 - 0.059 12.2 14.8 0.069 12.0 14.8 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4179 PF13786.6 CDJ39192.1 - 0.36 11.3 1.1 0.7 10.4 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Presenilin PF01080.17 CDJ39192.1 - 0.44 9.3 3.0 0.37 9.5 3.0 1.1 1 0 0 1 1 1 0 Presenilin R_equi_Vir PF05526.11 CDJ39192.1 - 1.1 9.1 4.1 1.7 8.5 4.1 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF1980 PF09323.10 CDJ39192.1 - 1.5 8.7 4.0 0.49 10.3 1.5 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) FAM199X PF15814.5 CDJ39192.1 - 4.2 6.3 6.8 0.79 8.7 3.7 1.3 1 1 0 1 1 1 0 Protein family FAM199X DUF4834 PF16118.5 CDJ39192.1 - 4.8 8.2 7.0 8.3 7.5 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FCSD-flav_bind PF09242.11 CDJ39192.1 - 6.5 7.2 7.4 24 5.3 0.8 2.5 1 1 1 2 2 2 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding eIF3_subunit PF08597.10 CDJ39192.1 - 8.1 6.3 13.8 13 5.6 13.8 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Med3 PF11593.8 CDJ39193.1 - 0.0072 15.6 17.1 0.0091 15.2 17.1 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ39193.1 - 0.012 16.0 14.1 0.013 15.8 14.1 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Rsc14 PF08586.10 CDJ39193.1 - 0.015 16.1 0.4 0.019 15.8 0.4 1.2 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit DUF4824 PF16106.5 CDJ39193.1 - 0.02 14.1 2.1 0.023 13.9 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) TFIIA PF03153.13 CDJ39193.1 - 0.058 13.4 14.7 0.063 13.3 14.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2232 PF09991.9 CDJ39193.1 - 0.077 12.2 0.1 0.088 12.0 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Spt20 PF12090.8 CDJ39193.1 - 0.098 12.3 13.2 0.12 12.0 13.2 1.1 1 0 0 1 1 1 0 Spt20 family Neuregulin PF02158.15 CDJ39193.1 - 0.16 11.3 5.0 0.19 11.0 5.0 1.0 1 0 0 1 1 1 0 Neuregulin intracellular region SUIM_assoc PF16619.5 CDJ39193.1 - 0.22 11.6 12.5 0.41 10.7 12.5 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ39193.1 - 0.27 10.1 8.5 0.29 10.0 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TALPID3 PF15324.6 CDJ39193.1 - 0.35 8.5 10.9 0.4 8.3 10.9 1.0 1 0 0 1 1 1 0 Hedgehog signalling target FAM199X PF15814.5 CDJ39193.1 - 0.43 9.6 2.8 0.51 9.3 2.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X TraT PF05818.12 CDJ39193.1 - 4.8 6.8 9.5 7.3 6.2 9.5 1.3 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein FAM70 PF14967.6 CDJ39193.1 - 7.6 5.9 7.2 8.6 5.7 7.2 1.1 1 0 0 1 1 1 0 FAM70 protein Methyltransf_15 PF09445.10 CDJ39194.1 - 0.0047 16.5 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase RskA PF10099.9 CDJ39194.1 - 0.0097 16.2 11.5 0.0097 16.2 11.5 2.6 2 1 0 2 2 2 1 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ39194.1 - 0.31 11.1 14.6 0.045 13.8 4.2 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ39194.1 - 5 6.0 9.6 0.78 8.6 4.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) zf-RanBP PF00641.18 CDJ39196.1 - 0.15 11.4 0.2 0.4 10.1 0.2 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others RskA PF10099.9 CDJ39197.1 - 0.00045 20.6 0.0 0.00045 20.6 0.0 29.1 8 5 11 23 23 23 4 Anti-sigma-K factor rskA INTS5_N PF14837.6 CDJ39198.1 - 0.066 12.8 0.7 0.1 12.2 0.7 1.3 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus CTI PF06934.11 CDJ39198.1 - 0.24 9.9 2.8 0.34 9.4 2.8 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) MRP-S27 PF10037.9 CDJ39198.1 - 0.31 9.9 6.8 0.44 9.4 6.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Presenilin PF01080.17 CDJ39198.1 - 0.66 8.7 4.1 1.3 7.7 4.1 1.3 1 0 0 1 1 1 0 Presenilin CpXC PF14353.6 CDJ39199.1 - 0.036 14.1 1.2 0.1 12.6 1.5 1.5 2 0 0 2 2 2 0 CpXC protein Zn-ribbon_8 PF09723.10 CDJ39199.1 - 0.16 12.1 3.5 4.3 7.5 0.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Cyclin PF08613.11 CDJ39200.1 - 5.4e-15 56.1 0.0 2.9e-14 53.8 0.0 2.3 2 0 0 2 2 2 1 Cyclin Arm PF00514.23 CDJ39203.1 - 1.6e-08 34.3 43.9 0.00014 21.7 0.8 9.0 9 1 1 10 10 10 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CDJ39203.1 - 0.012 16.1 0.4 0.012 16.1 0.4 7.0 7 2 0 7 7 7 0 HEAT-like repeat HEAT_2 PF13646.6 CDJ39203.1 - 0.4 11.1 10.3 8.1 6.9 0.0 4.7 4 0 0 4 4 4 0 HEAT repeats NOC3p PF07540.11 CDJ39204.1 - 1.4e-11 44.7 0.5 1.4e-11 44.7 0.5 2.7 2 1 0 2 2 2 1 Nucleolar complex-associated protein zf-met2 PF12907.7 CDJ39205.1 - 2.1e-19 69.3 2.0 3.4e-19 68.7 2.0 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 CDJ39205.1 - 4.9e-05 24.1 3.7 4.9e-05 24.1 3.7 1.8 2 0 0 2 2 2 1 4F5 protein family zf-BED PF02892.15 CDJ39205.1 - 0.11 12.6 1.1 0.11 12.5 0.2 1.5 2 0 0 2 2 2 0 BED zinc finger DSPc PF00782.20 CDJ39206.1 - 1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ39206.1 - 0.0011 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DEAD_assoc PF08494.11 CDJ39206.1 - 0.094 12.5 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 DEAD/H associated Maf PF02545.14 CDJ39207.1 - 3.2e-21 75.9 0.6 1.1e-09 38.3 0.0 2.9 2 1 0 2 2 2 2 Maf-like protein Efg1 PF10153.9 CDJ39208.1 - 6.3e-17 62.0 8.8 6.3e-17 62.0 8.8 2.0 2 0 0 2 2 2 1 rRNA-processing protein Efg1 DUF2336 PF10098.9 CDJ39208.1 - 0.17 11.3 6.6 0.26 10.7 5.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) Coatomer_WDAD PF04053.14 CDJ39209.1 - 3.8e-74 250.3 0.0 2.2e-73 247.8 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 CDJ39209.1 - 2.5e-72 243.9 0.0 3.5e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CDJ39209.1 - 6.3e-23 80.6 10.4 2.1e-07 31.5 0.5 5.9 7 0 0 7 7 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ39209.1 - 4.9e-12 46.0 0.3 4.5e-07 30.1 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ39209.1 - 0.0087 14.8 2.4 1.7 7.2 0.3 2.5 2 1 0 2 2 2 2 Nucleoporin Nup120/160 NRBF2_MIT PF17169.4 CDJ39209.1 - 0.018 15.3 0.2 0.054 13.7 0.2 1.8 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 TCL1_MTCP1 PF01840.17 CDJ39209.1 - 0.023 14.3 0.2 0.051 13.2 0.2 1.5 1 0 0 1 1 1 0 TCL1/MTCP1 family TPR_2 PF07719.17 CDJ39209.1 - 0.029 14.5 4.6 3.1 8.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CDJ39209.1 - 0.085 12.9 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Nucleoporin_N PF08801.11 CDJ39209.1 - 0.25 10.0 0.1 0.83 8.3 0.0 1.9 2 0 0 2 2 2 0 Nup133 N terminal like TPR_16 PF13432.6 CDJ39209.1 - 4.8 7.9 9.5 18 6.1 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_2 PF07724.14 CDJ39210.1 - 9.7e-52 175.5 0.0 2.7e-50 170.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CDJ39210.1 - 2.2e-33 114.3 0.7 2.2e-33 114.3 0.7 2.5 3 0 0 3 3 2 1 AAA lid domain AAA PF00004.29 CDJ39210.1 - 7.9e-24 84.6 0.0 1.8e-10 41.3 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CDJ39210.1 - 3.7e-20 71.8 0.3 2.2e-19 69.3 0.3 2.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 CDJ39210.1 - 4.8e-17 61.8 1.4 6.4e-09 35.8 0.1 3.7 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 CDJ39210.1 - 2e-13 50.6 0.0 1.5e-10 41.3 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CDJ39210.1 - 3.9e-07 29.9 0.0 5.2e-06 26.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CDJ39210.1 - 6.8e-07 29.4 0.0 0.043 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CDJ39210.1 - 2.5e-05 24.5 2.4 0.005 17.1 0.0 4.4 4 1 0 4 4 3 1 AAA domain AAA_16 PF13191.6 CDJ39210.1 - 3.4e-05 24.3 12.9 0.013 15.9 0.3 5.1 4 3 1 5 5 3 2 AAA ATPase domain RuvB_N PF05496.12 CDJ39210.1 - 5.6e-05 22.9 0.1 0.038 13.7 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 CDJ39210.1 - 0.00014 21.9 0.6 0.28 11.1 0.0 3.5 4 0 0 4 4 4 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 CDJ39210.1 - 0.00032 21.2 4.0 0.028 15.0 0.0 4.1 5 1 1 6 6 3 1 AAA domain AAA_7 PF12775.7 CDJ39210.1 - 0.00032 20.2 0.0 0.0063 16.0 0.0 2.4 2 1 0 2 2 2 1 P-loop containing dynein motor region DNA_pol3_delta2 PF13177.6 CDJ39210.1 - 0.0023 17.7 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase III, delta subunit IstB_IS21 PF01695.17 CDJ39210.1 - 0.0067 16.2 0.0 0.14 11.9 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 CDJ39210.1 - 0.007 15.7 0.1 0.057 12.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 CDJ39210.1 - 0.0082 15.5 0.2 2.5 7.5 0.0 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDJ39210.1 - 0.0091 15.9 0.0 0.36 10.7 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CDJ39210.1 - 0.017 14.2 0.0 0.049 12.7 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein Sulfatase_C PF14707.6 CDJ39210.1 - 0.022 15.5 0.1 0.071 13.8 0.1 1.9 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase RNA_helicase PF00910.22 CDJ39210.1 - 0.028 14.8 0.0 0.73 10.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 CDJ39210.1 - 0.032 14.8 0.0 0.21 12.1 0.0 2.4 3 0 0 3 3 1 0 ABC transporter DUF815 PF05673.13 CDJ39210.1 - 0.043 13.0 0.1 0.43 9.7 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 CDJ39210.1 - 0.046 13.6 0.4 1.3 8.9 0.0 3.4 4 1 0 4 4 4 0 RsgA GTPase AAA_30 PF13604.6 CDJ39210.1 - 0.056 13.2 0.2 1.3 8.7 0.0 3.1 3 1 0 3 3 2 0 AAA domain AAA_28 PF13521.6 CDJ39210.1 - 0.076 13.3 1.5 5.9 7.1 0.0 3.9 3 1 0 3 3 3 0 AAA domain AAA_17 PF13207.6 CDJ39210.1 - 0.088 13.2 0.1 2.7 8.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF4407 PF14362.6 CDJ39210.1 - 0.097 12.0 6.7 0.22 10.9 6.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TsaE PF02367.17 CDJ39210.1 - 0.099 12.6 0.1 1.3 9.0 0.0 2.8 4 0 0 4 4 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 CDJ39210.1 - 0.12 12.6 0.0 0.59 10.4 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 CDJ39210.1 - 0.12 12.3 0.1 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Fmp27_WPPW PF10359.9 CDJ39210.1 - 0.16 10.7 3.5 0.3 9.9 3.5 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain phage_tail_N PF08400.10 CDJ39210.1 - 0.23 11.4 1.1 1 9.4 0.3 2.5 3 0 0 3 3 1 0 Prophage tail fibre N-terminal DUF87 PF01935.17 CDJ39210.1 - 0.65 10.1 4.7 2 8.4 0.0 3.4 3 1 0 3 3 3 0 Helicase HerA, central domain AAA_33 PF13671.6 CDJ39210.1 - 1.1 9.4 4.0 2.6 8.2 0.0 3.4 5 0 0 5 5 2 0 AAA domain AAA_12 PF13087.6 CDJ39211.1 - 9.6e-23 80.8 0.0 1.1e-15 57.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CDJ39211.1 - 9.8e-13 48.5 0.0 5.5e-06 26.4 0.0 2.9 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 CDJ39211.1 - 2e-11 44.0 0.0 2e-11 44.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CDJ39211.1 - 2.2e-08 34.6 0.4 8.4e-08 32.7 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CDJ39211.1 - 0.00032 21.1 0.5 0.0024 18.3 0.1 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 CDJ39211.1 - 0.0016 18.9 0.0 0.0064 16.9 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CDJ39211.1 - 0.0017 18.3 0.1 0.0089 16.0 0.0 2.2 2 0 0 2 2 2 1 NACHT domain PhoH PF02562.16 CDJ39211.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Fer2_2 PF01799.20 CDJ39211.1 - 0.023 14.7 0.0 0.99 9.5 0.0 2.9 2 0 0 2 2 2 0 [2Fe-2S] binding domain DUF2075 PF09848.9 CDJ39211.1 - 0.056 12.7 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.13 CDJ39211.1 - 0.093 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DUF1180 PF06679.12 CDJ39212.1 - 0.92 9.9 8.4 1.4 9.4 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) LRRNT_2 PF08263.12 CDJ39213.1 - 0.19 12.1 1.4 11 6.4 0.2 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Asn_synthase PF00733.21 CDJ39215.1 - 2.2e-11 44.1 4.8 1.3e-05 25.1 0.7 3.2 2 1 0 2 2 2 2 Asparagine synthase Lectin_leg-like PF03388.13 CDJ39216.1 - 4.6e-13 49.0 0.2 1.1e-12 47.9 0.2 1.6 1 1 0 1 1 1 1 Legume-like lectin family Got1 PF04178.12 CDJ39217.1 - 8.9e-31 106.6 18.4 1.2e-30 106.2 18.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Sensor PF13796.6 CDJ39217.1 - 9 6.3 21.2 0.23 11.5 11.8 2.4 2 1 0 2 2 2 0 Putative sensor Kazal_1 PF00050.21 CDJ39218.1 - 3e-08 33.6 5.8 4.6e-08 33.0 5.8 1.3 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 CDJ39218.1 - 5.2e-08 32.9 6.7 1.3e-07 31.6 6.7 1.5 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Myb_DNA-binding PF00249.31 CDJ39219.1 - 3.8e-18 65.4 14.6 1.5e-11 44.3 1.1 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ39219.1 - 1e-17 64.1 2.4 3.2e-12 46.5 2.0 3.7 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_Cef PF11831.8 CDJ39219.1 - 6.6e-17 61.9 3.7 6.6e-17 61.9 3.7 4.1 4 1 0 4 4 4 1 pre-mRNA splicing factor component GSCFA PF08885.11 CDJ39219.1 - 0.019 14.6 0.1 0.044 13.4 0.1 1.6 1 0 0 1 1 1 0 GSCFA family TssC PF17541.2 CDJ39219.1 - 0.04 12.8 0.2 0.099 11.4 0.2 1.6 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Rap1_C PF11626.8 CDJ39219.1 - 0.28 11.3 6.5 0.41 10.8 0.1 3.5 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Phosducin PF02114.16 CDJ39219.1 - 0.44 9.4 3.9 1 8.3 3.9 1.5 1 0 0 1 1 1 0 Phosducin Chorein_N PF12624.7 CDJ39220.1 - 5e-10 39.5 0.0 1.5e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CDJ39220.1 - 6.2e-05 22.8 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 CDJ39220.1 - 0.00012 21.6 0.0 0.00041 19.8 0.0 1.8 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 Na_H_antiporter PF03553.14 CDJ39220.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Na+/H+ antiporter family Ribosomal_L31e PF01198.19 CDJ39221.1 - 5.3e-40 135.5 4.0 5.3e-40 135.5 4.0 1.6 1 1 1 2 2 2 1 Ribosomal protein L31e DUF4890 PF16231.5 CDJ39221.1 - 0.11 13.0 1.3 8.5 6.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) Rep_fac_C PF08542.11 CDJ39222.1 - 1.5e-12 47.7 0.0 4.7e-12 46.1 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CDJ39222.1 - 6.5e-12 45.5 0.7 1.1e-11 44.8 0.7 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CDJ39222.1 - 3e-05 24.4 0.0 7.7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 CDJ39222.1 - 0.0001 22.5 0.1 0.00059 20.1 0.0 2.3 2 0 0 2 2 2 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 CDJ39222.1 - 0.00058 19.7 1.1 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Macoilin PF09726.9 CDJ39222.1 - 0.00084 18.0 10.0 0.001 17.8 10.0 1.1 1 0 0 1 1 1 1 Macoilin family Sporozoite_P67 PF05642.11 CDJ39222.1 - 0.045 11.8 11.5 0.077 11.1 11.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA_16 PF13191.6 CDJ39222.1 - 0.055 13.9 0.3 0.099 13.0 0.3 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CDJ39222.1 - 0.1 12.8 1.3 0.32 11.3 1.3 1.9 1 1 0 1 1 1 0 AAA domain DUF1387 PF07139.11 CDJ39222.1 - 0.11 12.1 9.4 0.17 11.6 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Vma12 PF11712.8 CDJ39222.1 - 0.13 12.3 0.4 0.29 11.2 0.2 1.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Sec10 PF07393.11 CDJ39222.1 - 0.16 10.3 10.5 0.23 9.8 10.5 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Ndc1_Nup PF09531.10 CDJ39222.1 - 0.31 9.7 7.2 0.41 9.3 7.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.19 CDJ39222.1 - 0.32 10.9 10.8 0.43 10.5 10.8 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ39222.1 - 0.54 9.1 12.7 0.72 8.6 12.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain GCOM2 PF15328.6 CDJ39222.1 - 0.94 9.8 10.4 1.3 9.3 10.4 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 RAP1 PF07218.11 CDJ39222.1 - 1.5 7.0 18.3 2.1 6.5 18.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1635 PF07795.11 CDJ39222.1 - 1.8 8.4 9.9 3.3 7.5 9.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Lin-8 PF03353.15 CDJ39222.1 - 2.1 7.8 7.5 3.3 7.2 7.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Miga PF10265.9 CDJ39222.1 - 2.1 7.2 7.7 2.5 7.0 7.7 1.2 1 0 0 1 1 1 0 Mitoguardin NST1 PF13945.6 CDJ39222.1 - 2.2 8.3 11.7 3.8 7.6 11.7 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Presenilin PF01080.17 CDJ39222.1 - 4.1 6.0 10.3 5.6 5.6 10.3 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S9 PF00326.21 CDJ39223.1 - 1.4e-32 112.9 0.0 7.5e-24 84.4 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CDJ39223.1 - 0.0087 15.7 0.0 0.0087 15.7 0.0 4.3 3 2 0 5 5 5 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 CDJ39223.1 - 0.054 12.8 0.3 2.8 7.1 0.1 3.2 2 1 0 3 3 3 0 Serine aminopeptidase, S33 Esterase PF00756.20 CDJ39223.1 - 0.072 12.7 0.2 0.072 12.7 0.2 2.6 2 0 0 2 2 2 0 Putative esterase RAI1 PF08652.11 CDJ39223.1 - 8.4 6.7 0.0 8.4 6.7 0.0 3.2 3 0 0 3 3 3 0 RAI1 like PD-(D/E)XK nuclease Myosin_head PF00063.21 CDJ39225.1 - 3.8e-186 620.3 0.0 4.5e-186 620.0 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 CDJ39225.1 - 0.021 15.2 0.0 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CDJ39225.1 - 0.098 12.9 0.0 0.68 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain ICMT PF04140.14 CDJ39227.1 - 8.7e-22 77.4 0.8 8.7e-22 77.4 0.8 2.2 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDJ39227.1 - 1e-09 38.7 0.3 3.5e-09 37.0 0.3 2.0 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 CDJ39227.1 - 0.00037 20.1 1.5 0.00037 20.1 1.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 CDJ39227.1 - 0.0021 16.9 2.1 0.0036 16.1 2.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Ribosomal_60s PF00428.19 CDJ39227.1 - 0.075 13.6 4.4 0.16 12.5 4.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein UQ_con PF00179.26 CDJ39228.1 - 1.9e-47 160.5 0.0 2.1e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ39228.1 - 0.0049 16.6 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CDJ39228.1 - 0.0082 16.0 0.1 0.015 15.2 0.1 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 CDJ39228.1 - 0.16 12.2 0.3 0.22 11.8 0.3 1.4 1 1 0 1 1 1 0 RWD domain DUF4064 PF13273.6 CDJ39229.1 - 0.17 12.2 9.6 0.42 10.9 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) HSP20 PF00011.21 CDJ39231.1 - 4.5e-19 68.5 0.0 4.5e-19 68.5 0.0 2.4 3 1 0 3 3 3 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ39231.1 - 1.6e-08 34.0 0.0 2.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Spt20 PF12090.8 CDJ39231.1 - 0.0073 15.9 6.9 0.0073 15.9 6.9 4.4 3 1 1 4 4 4 2 Spt20 family BON PF04972.17 CDJ39231.1 - 0.15 12.4 0.0 0.15 12.4 0.0 2.5 3 0 0 3 3 3 0 BON domain Folate_carrier PF01770.18 CDJ39231.1 - 1.2 7.8 7.0 6 5.5 4.9 2.3 2 0 0 2 2 2 0 Reduced folate carrier OATP PF03137.20 CDJ39231.1 - 1.7 6.8 8.3 8.8 4.5 0.0 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SpoIIP PF07454.11 CDJ39231.1 - 3 7.2 23.4 0.21 11.0 8.4 3.4 4 0 0 4 4 4 0 Stage II sporulation protein P (SpoIIP) RskA PF10099.9 CDJ39232.1 - 1.6e-05 25.3 7.5 0.0026 18.1 0.4 2.6 3 0 0 3 3 3 2 Anti-sigma-K factor rskA K_channel_TID PF07941.11 CDJ39232.1 - 0.0042 17.5 7.7 0.0042 17.5 7.7 3.2 3 0 0 3 3 3 1 Potassium channel Kv1.4 tandem inactivation domain RRM_1 PF00076.22 CDJ39232.1 - 0.008 16.0 0.2 2.2 8.1 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RXLR PF16810.5 CDJ39232.1 - 1.9 8.9 13.5 0.93 9.9 3.1 2.7 3 0 0 3 3 3 0 RXLR phytopathogen effector protein, Avirulence activity Spore_III_AF PF09581.10 CDJ39232.1 - 8.8 6.3 14.3 1.3 9.0 0.4 2.6 2 1 1 3 3 3 0 Stage III sporulation protein AF (Spore_III_AF) Suf PF05843.14 CDJ39234.1 - 1.3 8.9 9.4 1.7 8.6 9.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ39234.1 - 1.8 7.3 6.6 2.2 7.0 6.6 1.3 1 0 0 1 1 1 0 Presenilin TAF4 PF05236.14 CDJ39234.1 - 7.9 6.1 17.6 9.3 5.9 17.6 1.3 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Ctr PF04145.15 CDJ39234.1 - 9.8 6.8 6.9 5 7.7 4.8 1.5 1 1 1 2 2 2 0 Ctr copper transporter family Utp14 PF04615.13 CDJ39235.1 - 2.9e-13 49.4 20.5 2.9e-13 49.4 20.5 2.0 1 1 1 2 2 2 1 Utp14 protein SR-25 PF10500.9 CDJ39235.1 - 9.1 5.8 28.0 4.6 6.8 11.4 2.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-CCCH PF00642.24 CDJ39236.1 - 0.00013 21.7 20.9 0.013 15.4 3.7 3.7 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ39236.1 - 0.0036 17.3 19.6 0.064 13.3 1.1 3.8 4 0 0 4 4 4 2 Zinc finger domain SUIM_assoc PF16619.5 CDJ39236.1 - 0.014 15.4 2.2 0.014 15.4 2.2 11.3 6 2 5 11 11 11 0 Unstructured region C-term to UIM in Ataxin3 zf-CCCH_2 PF14608.6 CDJ39236.1 - 0.064 13.8 16.2 2 9.0 0.3 3.7 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CDJ39236.1 - 0.067 13.0 12.9 0.051 13.4 2.9 3.2 3 0 0 3 3 3 0 CCCH-type zinc finger DHHC PF01529.20 CDJ39237.1 - 1.6e-28 99.5 13.2 1.7e-28 99.4 13.2 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF4400 PF14348.6 CDJ39238.1 - 0.82 9.1 0.0 0.82 9.1 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4400) MMR1 PF08505.10 CDJ39238.1 - 1.3 9.3 32.3 0.72 10.1 12.6 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Merozoite_SPAM PF07133.11 CDJ39238.1 - 6.1 6.8 18.5 0.29 11.1 12.8 1.7 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) LTV PF04180.14 CDJ39238.1 - 6.8 6.3 24.9 0.1 12.3 12.1 2.3 2 0 0 2 2 2 0 Low temperature viability protein RL10P_insert PF17777.1 CDJ39239.1 - 3.1e-17 62.3 0.1 7.5e-17 61.1 0.1 1.7 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CDJ39239.1 - 1.1e-12 47.9 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 CCSAP PF15748.5 CDJ39242.1 - 0.0099 16.1 0.3 0.014 15.6 0.3 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated Acyl_transf_1 PF00698.21 CDJ39243.1 - 2.6e-16 60.0 3.1 4.9e-16 59.1 3.1 1.4 1 1 0 1 1 1 1 Acyl transferase domain Cpn60_TCP1 PF00118.24 CDJ39244.1 - 6.4e-31 107.5 0.0 7e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Lin-8 PF03353.15 CDJ39245.1 - 0.048 13.2 8.9 0.089 12.3 8.9 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist YppG PF14179.6 CDJ39245.1 - 0.47 11.2 15.9 0.4 11.4 13.3 2.2 2 0 0 2 2 2 0 YppG-like protein PIEZO PF15917.5 CDJ39245.1 - 0.57 9.6 7.5 0.95 8.9 7.5 1.2 1 0 0 1 1 1 0 Piezo Apt1 PF10351.9 CDJ39245.1 - 3.4 6.4 14.1 4.4 6.0 14.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spt20 PF12090.8 CDJ39245.1 - 6.1 6.4 18.5 14 5.2 18.5 1.7 1 0 0 1 1 1 0 Spt20 family DCP2 PF05026.13 CDJ39247.1 - 2.6e-14 53.3 0.6 6.9e-14 51.9 0.6 1.8 1 0 0 1 1 1 1 Dcp2, box A domain LsmAD PF06741.13 CDJ39247.1 - 0.022 15.3 0.1 0.022 15.3 0.1 4.1 5 0 0 5 5 5 0 LsmAD domain AAA PF00004.29 CDJ39249.1 - 7.7e-32 110.5 0.0 7.8e-25 87.8 0.0 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ39249.1 - 1.3e-05 25.6 0.2 1.3e-05 25.6 0.2 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 CDJ39249.1 - 2.1e-05 24.7 0.4 0.00014 22.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CDJ39249.1 - 0.00017 21.9 0.8 0.00088 19.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CDJ39249.1 - 0.00024 20.9 0.1 0.0035 17.1 0.0 2.5 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDJ39249.1 - 0.00029 21.1 0.1 0.013 15.7 0.0 3.0 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.14 CDJ39249.1 - 0.00038 20.5 0.0 0.001 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CDJ39249.1 - 0.00046 20.0 0.3 0.0011 18.7 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_lid_3 PF17862.1 CDJ39249.1 - 0.001 18.8 0.5 0.0039 17.0 0.5 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 CDJ39249.1 - 0.0016 19.0 0.0 0.004 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF755 PF05501.11 CDJ39249.1 - 0.0017 18.6 10.1 0.0017 18.6 10.1 3.4 4 0 0 4 4 3 1 Domain of unknown function (DUF755) Mg_chelatase PF01078.21 CDJ39249.1 - 0.0022 17.4 0.0 0.0053 16.2 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 CDJ39249.1 - 0.003 18.1 0.1 0.0082 16.7 0.0 1.7 2 0 0 2 2 1 1 ABC transporter SUIM_assoc PF16619.5 CDJ39249.1 - 0.0036 17.3 1.2 0.0036 17.3 1.2 3.5 3 1 0 3 3 1 1 Unstructured region C-term to UIM in Ataxin3 RNA_helicase PF00910.22 CDJ39249.1 - 0.0055 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TFIIA PF03153.13 CDJ39249.1 - 0.012 15.6 12.2 0.035 14.1 3.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AAA_17 PF13207.6 CDJ39249.1 - 0.014 15.9 0.0 0.061 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF1645 PF07816.11 CDJ39249.1 - 0.015 15.9 4.0 0.015 15.9 4.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) CPT PF07931.12 CDJ39249.1 - 0.025 14.4 0.1 2.3 8.0 0.0 2.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Rad17 PF03215.15 CDJ39249.1 - 0.046 13.6 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 CDJ39249.1 - 0.059 13.1 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 CDJ39249.1 - 0.065 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 CDJ39249.1 - 0.1 12.5 0.1 0.33 10.8 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 CDJ39249.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF702 PF05142.12 CDJ39249.1 - 0.13 12.8 6.3 1.2 9.6 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF702) AAA_2 PF07724.14 CDJ39249.1 - 0.15 12.1 0.0 0.48 10.5 0.0 1.9 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CDJ39249.1 - 0.18 11.0 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain DUF4603 PF15376.6 CDJ39249.1 - 0.2 9.0 4.1 0.45 7.9 4.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Spt20 PF12090.8 CDJ39249.1 - 0.44 10.1 16.3 0.14 11.8 4.7 2.2 2 0 0 2 2 2 0 Spt20 family Hydin_ADK PF17213.3 CDJ39249.1 - 0.58 10.4 13.2 2.7 8.2 0.0 3.5 2 1 1 3 3 2 0 Hydin Adenylate kinase-like domain SKI PF01202.22 CDJ39249.1 - 0.67 10.1 3.2 2.1 8.4 0.0 2.7 2 1 1 3 3 3 0 Shikimate kinase TetR_C_12 PF16914.5 CDJ39249.1 - 2.1 8.5 8.6 0.22 11.6 2.6 2.2 2 0 0 2 2 2 0 Bacterial transcriptional repressor C-terminal CCDC53 PF10152.9 CDJ39249.1 - 5 7.5 9.6 7.4 7.0 1.5 2.9 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Lin-8 PF03353.15 CDJ39249.1 - 5 6.6 8.6 6.3 6.3 2.5 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Mt_ATP-synt_D PF05873.12 CDJ39250.1 - 0.00062 19.6 0.1 0.00088 19.2 0.1 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Dehalogenase PF13486.6 CDJ39250.1 - 0.024 14.0 0.1 0.038 13.4 0.1 1.3 1 0 0 1 1 1 0 Reductive dehalogenase subunit SurA_N_2 PF13623.6 CDJ39250.1 - 0.076 12.9 2.8 0.16 11.8 2.8 1.5 1 0 0 1 1 1 0 SurA N-terminal domain Lant_dehydr_C PF14028.6 CDJ39250.1 - 0.19 11.3 4.0 0.27 10.7 4.0 1.3 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term GrpE PF01025.19 CDJ39251.1 - 3e-34 118.1 1.0 4e-34 117.7 1.0 1.1 1 0 0 1 1 1 1 GrpE DUF1664 PF07889.12 CDJ39251.1 - 0.077 13.0 0.9 0.14 12.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) STAG PF08514.11 CDJ39251.1 - 0.16 11.9 1.1 0.38 10.7 1.1 1.6 1 0 0 1 1 1 0 STAG domain DUF4914 PF16260.5 CDJ39251.1 - 0.23 9.5 2.6 0.28 9.2 2.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4914) SpoIIIAH PF12685.7 CDJ39251.1 - 1.4 8.7 10.2 2 8.2 10.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein TFIIA PF03153.13 CDJ39252.1 - 0.0021 18.1 8.9 0.0024 17.9 8.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 CDJ39252.1 - 0.037 13.2 5.6 0.045 13.0 5.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 CDJ39252.1 - 0.17 9.0 4.5 0.19 8.8 4.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 CDJ39252.1 - 0.28 10.5 0.4 0.33 10.3 0.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2828 PF11443.8 CDJ39252.1 - 0.65 8.0 3.1 0.85 7.6 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4551 PF15087.6 CDJ39252.1 - 0.84 8.4 7.0 1.1 8.0 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF755 PF05501.11 CDJ39252.1 - 2.6 8.3 25.5 2.1 8.7 14.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) UPF0560 PF10577.9 CDJ39252.1 - 3.3 6.1 9.2 4.3 5.7 9.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3827 PF12877.7 CDJ39252.1 - 6.5 5.0 10.5 8.2 4.7 10.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) TMEM247 PF15444.6 CDJ39253.1 - 0.016 15.2 0.1 0.016 15.2 0.1 3.4 4 0 0 4 4 4 0 Transmembrane protein 247 DUF4614 PF15391.6 CDJ39254.1 - 0.24 11.4 13.7 0.28 11.2 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) EPL1 PF10513.9 CDJ39254.1 - 0.25 11.7 2.0 0.3 11.5 2.0 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Pneumo_att_G PF05539.11 CDJ39254.1 - 1.2 8.6 13.7 1.4 8.4 13.7 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G CDK2AP PF09806.9 CDJ39254.1 - 1.8 8.5 31.3 2.2 8.3 31.3 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein NST1 PF13945.6 CDJ39254.1 - 4 7.5 7.2 4.6 7.3 7.2 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator RIFIN PF02009.16 CDJ39254.1 - 5.8 6.7 14.2 7.8 6.3 14.2 1.3 1 0 0 1 1 1 0 Rifin DUF966 PF06136.13 CDJ39254.1 - 9.3 5.8 14.2 10 5.7 14.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) NPR3 PF03666.13 CDJ39254.1 - 9.5 4.9 7.1 10 4.8 7.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Spt20 PF12090.8 CDJ39255.1 - 0.54 9.8 19.1 0.072 12.7 10.7 2.6 2 0 0 2 2 2 0 Spt20 family RskA PF10099.9 CDJ39255.1 - 4 7.7 35.9 16 5.8 4.2 4.6 1 1 0 2 2 2 0 Anti-sigma-K factor rskA Pkinase PF00069.25 CDJ39256.1 - 7.3e-11 41.9 0.1 7.7e-11 41.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ39256.1 - 4.2e-07 29.5 0.1 4.7e-07 29.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase SR-25 PF10500.9 CDJ39257.1 - 0.073 12.7 1.2 0.093 12.3 1.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.11 CDJ39257.1 - 0.19 11.6 3.0 0.11 12.4 1.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) PRIMA1 PF16101.5 CDJ39257.1 - 0.21 11.6 0.2 0.21 11.6 0.2 1.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 LAG1-DNAbind PF09271.11 CDJ39258.1 - 0.13 12.9 0.8 0.28 11.8 0.2 1.8 2 0 0 2 2 2 0 LAG1, DNA binding CPSF100_C PF13299.6 CDJ39258.1 - 4 7.6 9.7 2.2 8.4 6.7 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Cwf_Cwc_15 PF04889.12 CDJ39258.1 - 4.2 7.0 13.4 0.29 10.8 8.3 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Androgen_recep PF02166.16 CDJ39261.1 - 0.11 11.3 2.2 8.9 5.0 3.0 2.0 2 0 0 2 2 2 0 Androgen receptor Ribosomal_L17 PF01196.19 CDJ39262.1 - 2.4e-18 66.8 0.1 3.2e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 Caskin1-CID PF16600.5 CDJ39263.1 - 0.13 12.9 5.8 0.29 11.8 5.8 1.6 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain TraG_N PF07916.11 CDJ39263.1 - 0.5 9.2 3.9 0.63 8.8 3.9 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region SR-25 PF10500.9 CDJ39263.1 - 0.8 9.3 8.7 1.1 8.8 8.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Androgen_recep PF02166.16 CDJ39264.1 - 0.0097 14.8 2.3 0.011 14.7 2.3 1.1 1 0 0 1 1 1 1 Androgen receptor DUF1180 PF06679.12 CDJ39264.1 - 0.078 13.4 0.1 0.085 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TMEM154 PF15102.6 CDJ39264.1 - 0.18 11.7 0.7 0.26 11.2 0.7 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF5373 PF17343.2 CDJ39264.1 - 0.21 11.4 6.0 0.26 11.1 6.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5373) Spt20 PF12090.8 CDJ39264.1 - 0.39 10.3 7.6 0.47 10.0 7.6 1.2 1 0 0 1 1 1 0 Spt20 family APG6_N PF17675.1 CDJ39266.1 - 0.049 14.2 5.6 0.099 13.2 5.6 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region USP8_interact PF08941.10 CDJ39268.1 - 0.42 10.4 6.1 0.54 10.0 6.1 1.2 1 0 0 1 1 1 0 USP8 interacting SPX PF03105.19 CDJ39268.1 - 0.45 10.4 29.3 0.53 10.1 29.3 1.1 1 0 0 1 1 1 0 SPX domain Tmemb_cc2 PF10267.9 CDJ39268.1 - 1.7 7.7 24.0 1.9 7.5 24.0 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Roughex PF06020.11 CDJ39268.1 - 4.7 6.2 15.3 7.7 5.5 15.3 1.3 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 CDJ39268.1 - 5.1 7.0 29.3 6.3 6.7 29.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ERM PF00769.19 CDJ39268.1 - 9 6.0 24.4 11 5.8 24.4 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Aminotran_1_2 PF00155.21 CDJ39270.1 - 9.9e-73 245.4 0.0 1.1e-72 245.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CDC45 PF02724.14 CDJ39271.1 - 0.01 14.2 7.9 0.012 13.9 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4045 PF13254.6 CDJ39271.1 - 0.029 14.0 22.0 0.036 13.7 22.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) TFIIA PF03153.13 CDJ39271.1 - 0.068 13.2 54.2 0.11 12.5 54.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ39271.1 - 0.1 11.4 23.2 0.13 11.0 23.2 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CDJ39271.1 - 0.29 8.2 18.4 0.34 8.0 18.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF778 PF05608.12 CDJ39271.1 - 0.65 10.3 7.7 1 9.7 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF778) ALMT PF11744.8 CDJ39271.1 - 0.96 8.2 17.7 1.3 7.8 17.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF913 PF06025.12 CDJ39271.1 - 1.5 7.7 10.0 2 7.3 10.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RIFIN PF02009.16 CDJ39271.1 - 1.6 8.6 12.1 2.1 8.2 12.1 1.1 1 0 0 1 1 1 0 Rifin SMN PF06003.12 CDJ39271.1 - 2.1 7.6 12.7 3.2 6.9 12.7 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Otopetrin PF03189.13 CDJ39271.1 - 3.3 6.4 4.8 4.3 6.0 4.8 1.2 1 0 0 1 1 1 0 Otopetrin PAT1 PF09770.9 CDJ39271.1 - 3.9 5.6 44.6 4.8 5.3 44.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rrn6 PF10214.9 CDJ39271.1 - 3.9 5.8 28.3 4.6 5.6 28.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SLC12 PF03522.15 CDJ39271.1 - 5.4 5.9 20.2 7.5 5.5 20.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 eIF-3_zeta PF05091.12 CDJ39271.1 - 6.7 5.6 26.0 9.1 5.1 26.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLN3 PF02487.17 CDJ39271.1 - 9.5 5.2 11.2 13 4.7 11.2 1.4 1 0 0 1 1 1 0 CLN3 protein NPR3 PF03666.13 CDJ39271.1 - 9.5 4.9 23.1 14 4.3 23.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Thioredoxin PF00085.20 CDJ39272.1 - 1.4e-11 44.3 0.0 1.7e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 CDJ39272.1 - 0.0026 17.5 0.0 0.003 17.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 CDJ39272.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Redoxin Helicase_C PF00271.31 CDJ39273.1 - 8.9e-12 45.3 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IMUP PF15761.5 CDJ39274.1 - 0.012 16.3 1.4 0.014 16.0 1.4 1.1 1 0 0 1 1 1 0 Immortalisation up-regulated protein HEAT_2 PF13646.6 CDJ39275.1 - 7.5e-14 51.9 10.4 3e-12 46.8 2.9 2.4 1 1 0 2 2 2 2 HEAT repeats PC_rep PF01851.22 CDJ39275.1 - 3.4e-11 43.0 9.0 0.002 18.5 2.6 3.7 4 0 0 4 4 4 3 Proteasome/cyclosome repeat HEAT PF02985.22 CDJ39275.1 - 9.7e-07 28.5 3.5 0.17 12.2 0.1 4.4 4 0 0 4 4 4 3 HEAT repeat Dynein_IC2 PF11540.8 CDJ39275.1 - 0.22 11.5 0.1 0.41 10.6 0.1 1.4 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 DUF4045 PF13254.6 CDJ39278.1 - 6 6.4 31.0 6.5 6.3 31.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DnaJ PF00226.31 CDJ39280.1 - 9.8e-13 48.0 0.9 2.3e-12 46.9 0.9 1.6 1 1 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 CDJ39281.1 - 9.6e-37 124.6 0.4 3.6e-18 65.1 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ39281.1 - 1e-08 34.8 0.0 0.00037 20.1 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ39281.1 - 2.8e-08 33.8 0.0 0.0084 16.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 CDJ39281.1 - 0.0016 18.7 0.1 0.52 10.5 0.0 2.8 2 1 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RNA_bind PF08675.11 CDJ39281.1 - 0.0075 16.3 0.1 0.57 10.2 0.0 2.7 2 2 0 2 2 2 1 RNA binding domain RRM_3 PF08777.11 CDJ39281.1 - 0.045 13.8 0.1 16 5.6 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif NTP_transferase PF00483.23 CDJ39282.1 - 2e-13 50.5 0.0 2e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CDJ39282.1 - 1.6e-07 31.9 0.0 1.6e-07 31.8 0.0 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain SMC_N PF02463.19 CDJ39284.1 - 3.4e-27 95.3 2.6 1.3e-26 93.4 2.6 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CDJ39284.1 - 5.1e-10 39.6 0.1 9.2e-10 38.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 CDJ39284.1 - 8e-10 39.6 9.7 2.1e-08 34.9 9.7 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 CDJ39284.1 - 9.5e-08 32.2 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ39284.1 - 2.6e-07 30.3 0.0 5.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CDJ39284.1 - 4.5e-05 24.0 0.6 0.00011 22.7 0.6 1.6 1 1 0 1 1 1 1 ABC transporter DUF3987 PF13148.6 CDJ39284.1 - 0.0012 18.0 0.1 0.0012 18.0 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_27 PF13514.6 CDJ39284.1 - 0.013 15.1 1.2 0.022 14.4 0.1 2.0 1 1 1 2 2 2 0 AAA domain Ribosomal_60s PF00428.19 CDJ39284.1 - 0.024 15.2 7.4 0.024 15.2 7.4 3.3 2 1 1 3 3 3 0 60s Acidic ribosomal protein AAA_16 PF13191.6 CDJ39284.1 - 0.029 14.8 0.2 0.029 14.8 0.2 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 CDJ39284.1 - 0.067 13.5 0.3 0.067 13.5 0.3 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDJ39284.1 - 0.073 13.4 0.1 0.15 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain MukB PF04310.12 CDJ39284.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 MukB N-terminal TFIIA PF03153.13 CDJ39284.1 - 1.8 8.4 20.6 0.22 11.5 15.0 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MSP1_C PF07462.11 CDJ39287.1 - 9.3 4.8 10.2 11 4.6 10.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus tRNA-synt_1e PF01406.19 CDJ39290.1 - 9.9e-56 189.3 0.0 1.2e-55 189.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.25 CDJ39291.1 - 6.2e-09 35.6 0.0 1.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ39291.1 - 0.00085 18.7 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase SUIM_assoc PF16619.5 CDJ39291.1 - 0.18 11.9 42.1 0.22 11.6 16.5 3.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Trp_oprn_chp PF09534.10 CDJ39291.1 - 0.58 9.9 15.5 0.079 12.8 5.4 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pkinase_fungal PF17667.1 CDJ39291.1 - 0.6 8.8 0.0 0.6 8.8 0.0 2.9 1 1 1 2 2 2 0 Fungal protein kinase Med15 PF09606.10 CDJ39291.1 - 4.3 5.9 42.9 6.8 5.2 42.9 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Med3 PF11593.8 CDJ39292.1 - 4.9 6.2 14.5 6.2 5.9 14.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FMN_red PF03358.15 CDJ39293.1 - 0.008 15.9 0.0 0.008 15.9 0.0 2.7 3 0 0 3 3 3 1 NADPH-dependent FMN reductase IMUP PF15761.5 CDJ39293.1 - 7.9 7.2 26.8 1.1 10.0 6.5 3.2 3 0 0 3 3 3 0 Immortalisation up-regulated protein Spt20 PF12090.8 CDJ39294.1 - 0.15 11.7 32.7 0.7 9.5 16.6 2.1 2 0 0 2 2 2 0 Spt20 family DUF543 PF04418.12 CDJ39296.1 - 0.0012 18.8 0.1 0.0018 18.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF543) E_Pc_C PF06752.12 CDJ39296.1 - 0.064 13.3 0.3 0.064 13.3 0.3 1.6 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus SUIM_assoc PF16619.5 CDJ39298.1 - 0.00053 20.0 3.5 0.00053 20.0 3.5 3.5 3 1 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 DUF2967 PF11179.8 CDJ39298.1 - 0.15 10.1 3.2 0.36 8.9 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) PorB PF11565.8 CDJ39298.1 - 2 8.9 6.4 15 6.0 0.1 2.4 2 0 0 2 2 2 0 Alpha helical Porin B Dehydrin PF00257.19 CDJ39298.1 - 4.5 7.8 13.1 0.96 10.0 5.4 2.4 2 1 0 2 2 2 0 Dehydrin DnaJ-X PF14308.6 CDJ39299.1 - 0.00027 20.5 0.8 0.00033 20.2 0.8 1.0 1 0 0 1 1 1 1 X-domain of DnaJ-containing UPF0560 PF10577.9 CDJ39299.1 - 0.021 13.3 5.0 0.021 13.4 5.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TFIIA PF03153.13 CDJ39299.1 - 0.032 14.2 11.3 0.03 14.3 11.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NUC194 PF08163.12 CDJ39299.1 - 0.057 12.3 2.8 0.059 12.3 2.8 1.0 1 0 0 1 1 1 0 NUC194 domain Spt20 PF12090.8 CDJ39299.1 - 0.18 11.4 16.8 0.21 11.2 16.8 1.1 1 0 0 1 1 1 0 Spt20 family NEMP PF10225.9 CDJ39299.1 - 0.2 11.3 2.5 0.22 11.1 2.5 1.0 1 0 0 1 1 1 0 NEMP family DUF4834 PF16118.5 CDJ39299.1 - 1.4 9.9 5.7 1.8 9.6 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ39299.1 - 1.6 7.6 14.7 1.7 7.5 14.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ39299.1 - 8.2 5.3 24.9 9.2 5.1 24.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 MORN PF02493.20 CDJ39300.1 - 4.6e-11 41.9 14.2 0.00016 21.4 0.9 4.6 4 0 0 4 4 4 3 MORN repeat SAM_1 PF00536.30 CDJ39300.1 - 5.8e-06 26.7 0.1 3.8e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDJ39300.1 - 0.047 13.8 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ndc1_Nup PF09531.10 CDJ39301.1 - 0.34 9.6 2.7 0.38 9.4 2.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Herpes_UL32 PF06070.11 CDJ39301.1 - 1 7.0 8.2 1.3 6.6 8.2 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 TFIIA PF03153.13 CDJ39301.1 - 7.1 6.5 22.1 9.2 6.1 22.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EIF4E-T PF10477.9 CDJ39303.1 - 1.5e-07 30.7 30.3 1.5e-07 30.7 30.3 6.1 5 1 2 7 7 7 2 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E LRR_8 PF13855.6 CDJ39303.1 - 0.0023 17.6 1.9 0.0023 17.6 1.9 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CDJ39303.1 - 0.029 14.8 5.0 0.26 11.8 1.8 2.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF4763 PF15960.5 CDJ39304.1 - 0.0088 15.4 8.1 0.011 15.1 8.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) Ribosomal_L23 PF00276.20 CDJ39305.1 - 5.6e-08 33.1 0.1 8.4e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 Arm PF00514.23 CDJ39306.1 - 2e-72 237.2 38.1 5.1e-14 51.7 0.0 9.4 11 0 0 11 11 11 7 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CDJ39306.1 - 2.1e-13 50.4 4.2 2e-08 34.5 0.1 12.8 11 4 3 14 14 14 3 HEAT-like repeat HEAT PF02985.22 CDJ39306.1 - 6.9e-11 41.4 1.8 0.0002 21.3 0.0 6.3 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 CDJ39306.1 - 3e-10 40.4 1.2 2.3e-06 27.9 0.0 6.8 5 1 3 8 8 8 3 HEAT repeats Pex14_N PF04695.13 CDJ39306.1 - 0.0092 16.6 5.3 0.0092 16.6 5.3 6.4 6 1 0 6 6 6 2 Peroxisomal membrane anchor protein (Pex14p) conserved region V-ATPase_H_C PF11698.8 CDJ39306.1 - 0.013 15.6 0.0 1.7 8.8 0.0 3.1 2 1 2 4 4 4 0 V-ATPase subunit H RICTOR_V PF14668.6 CDJ39306.1 - 0.048 13.9 0.3 4.1 7.7 0.0 3.7 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF1361 PF07099.11 CDJ39308.1 - 0.066 13.2 0.2 0.24 11.4 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1361) DUF4529 PF15032.6 CDJ39308.1 - 0.069 12.3 0.7 0.099 11.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) AAA_23 PF13476.6 CDJ39309.1 - 0.0038 17.8 3.6 0.0046 17.5 3.6 1.1 1 0 0 1 1 1 1 AAA domain Peptidase_U57 PF05582.12 CDJ39309.1 - 2 7.6 8.7 2.9 7.1 8.7 1.1 1 0 0 1 1 1 0 YabG peptidase U57 ORC5_C PF14630.6 CDJ39310.1 - 1.8e-17 63.8 0.0 2.8e-17 63.2 0.0 1.4 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus K_channel_TID PF07941.11 CDJ39310.1 - 0.011 16.2 7.1 0.011 16.2 7.1 5.8 6 1 0 6 6 6 0 Potassium channel Kv1.4 tandem inactivation domain Presenilin PF01080.17 CDJ39311.1 - 0.00082 18.2 9.5 0.0019 17.0 9.5 1.6 1 0 0 1 1 1 1 Presenilin DUF1980 PF09323.10 CDJ39311.1 - 0.013 15.4 5.8 0.034 14.1 5.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) MAJIN PF15077.6 CDJ39311.1 - 0.02 14.7 6.0 0.11 12.3 6.9 1.8 2 0 0 2 2 2 0 Membrane-anchored junction protein SID-1_RNA_chan PF13965.6 CDJ39311.1 - 0.038 12.4 2.7 0.06 11.8 2.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF5523 PF17661.1 CDJ39311.1 - 0.24 11.1 21.7 0.54 9.9 21.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Serinc PF03348.15 CDJ39311.1 - 1.6 7.6 4.5 3.2 6.6 4.5 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) CDC45 PF02724.14 CDJ39311.1 - 1.7 6.8 17.3 3.6 5.8 17.3 1.5 1 0 0 1 1 1 0 CDC45-like protein Otopetrin PF03189.13 CDJ39311.1 - 1.7 7.4 4.1 3.2 6.5 4.1 1.3 1 0 0 1 1 1 0 Otopetrin Baculo_PP31 PF05311.11 CDJ39311.1 - 1.8 8.0 9.5 6.1 6.2 9.5 1.9 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) eIF-3_zeta PF05091.12 CDJ39311.1 - 2 7.3 21.6 3.9 6.4 21.6 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 CDJ39311.1 - 2.3 8.0 21.4 7.2 6.4 21.4 1.8 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 CDJ39311.1 - 3 7.2 19.0 5.8 6.3 19.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) VIR_N PF15912.5 CDJ39311.1 - 5.7 6.5 11.9 11 5.6 11.9 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal DUF4050 PF13259.6 CDJ39311.1 - 6 7.2 20.1 3.9 7.8 13.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4050) LMBR1 PF04791.16 CDJ39311.1 - 6.6 5.5 6.6 19 4.0 6.6 1.7 1 0 0 1 1 1 0 LMBR1-like membrane protein Macoilin PF09726.9 CDJ39313.1 - 0.71 8.4 40.3 0.91 8.0 40.3 1.1 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 CDJ39313.1 - 2.4 6.3 24.4 2.7 6.2 24.4 1.2 1 0 0 1 1 1 0 CDC45-like protein ketoacyl-synt PF00109.26 CDJ39315.1 - 3.9e-19 69.2 8.0 3.9e-19 69.2 8.0 3.6 3 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CDJ39315.1 - 7e-14 51.9 3.1 1.7e-13 50.6 0.0 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain SARAF PF06682.12 CDJ39315.1 - 6.4e-07 29.3 9.5 0.015 14.9 6.9 3.4 2 2 2 4 4 4 3 SOCE-associated regulatory factor of calcium homoeostasis DUF4079 PF13301.6 CDJ39315.1 - 0.051 13.7 1.7 0.49 10.5 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF4710 PF15828.5 CDJ39315.1 - 0.14 12.2 3.5 8.2 6.6 0.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4710) Tic110 PF16940.5 CDJ39315.1 - 0.38 9.2 5.8 0.91 7.9 5.8 1.6 1 0 0 1 1 1 0 Chloroplast envelope transporter LMBR1 PF04791.16 CDJ39315.1 - 1.4 7.8 3.5 9.3 5.0 0.6 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein MASE2 PF05230.11 CDJ39315.1 - 1.9 8.6 4.8 3.3 7.9 0.0 3.8 4 0 0 4 4 4 0 MASE2 domain GCV_T PF01571.21 CDJ39316.1 - 3.5e-08 33.1 0.0 0.00036 20.0 0.0 2.1 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain PRP38_assoc PF12871.7 CDJ39316.1 - 0.0054 17.3 27.7 0.0054 17.3 27.7 2.3 2 0 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term IMUP PF15761.5 CDJ39316.1 - 0.81 10.4 9.8 1.6 9.5 9.8 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF755 PF05501.11 CDJ39316.1 - 1.3 9.3 15.9 2.7 8.3 15.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF2428 PF10350.9 CDJ39317.1 - 0.00019 20.8 3.2 0.0002 20.7 3.2 1.1 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) PAP_RNA-bind PF04926.15 CDJ39317.1 - 0.039 13.6 5.3 0.044 13.4 5.3 1.2 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain Peptidase_S49_N PF08496.10 CDJ39317.1 - 0.078 13.0 7.8 0.091 12.8 7.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Connexin PF00029.19 CDJ39317.1 - 0.092 12.5 5.0 0.094 12.5 5.0 1.0 1 0 0 1 1 1 0 Connexin Orf78 PF06024.12 CDJ39317.1 - 0.15 12.4 4.5 0.2 11.9 4.2 1.3 1 1 0 1 1 1 0 Orf78 (ac78) Activator_LAG-3 PF11498.8 CDJ39317.1 - 0.16 10.9 37.5 0.17 10.8 37.5 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 NEMP PF10225.9 CDJ39317.1 - 0.19 11.4 7.1 0.21 11.2 7.1 1.1 1 0 0 1 1 1 0 NEMP family OATP PF03137.20 CDJ39317.1 - 0.29 9.4 3.8 0.27 9.5 3.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.18 CDJ39317.1 - 0.3 9.8 4.3 0.31 9.7 4.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF868 PF05910.12 CDJ39317.1 - 0.3 10.7 4.9 0.35 10.5 4.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) TMEM215 PF15746.5 CDJ39317.1 - 0.41 10.1 2.2 0.51 9.8 2.2 1.1 1 0 0 1 1 1 0 TMEM215 family SpoIIP PF07454.11 CDJ39317.1 - 0.51 9.7 8.7 0.55 9.6 8.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pex14_N PF04695.13 CDJ39317.1 - 0.59 10.8 15.2 0.84 10.3 15.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ORC_WH_C PF18137.1 CDJ39317.1 - 0.61 10.2 11.0 1 9.4 11.0 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal MMR1 PF08505.10 CDJ39317.1 - 0.63 10.3 15.0 0.7 10.1 15.0 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein eIF-3_zeta PF05091.12 CDJ39317.1 - 0.68 8.8 15.2 0.72 8.8 15.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.17 CDJ39317.1 - 0.71 10.0 9.2 0.82 9.8 9.2 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 CDJ39317.1 - 0.78 9.5 11.1 0.92 9.3 11.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 CDJ39317.1 - 0.87 9.5 11.3 0.92 9.4 11.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TERB2 PF15101.6 CDJ39317.1 - 1.1 9.3 12.3 1.1 9.2 12.3 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Serinc PF03348.15 CDJ39317.1 - 1.2 8.0 5.9 1.4 7.8 5.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Paf1 PF03985.13 CDJ39317.1 - 1.7 7.6 14.2 1.9 7.4 14.2 1.0 1 0 0 1 1 1 0 Paf1 UPF0560 PF10577.9 CDJ39317.1 - 1.8 6.9 15.1 2.3 6.6 15.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 tRNA-synt_1c PF00749.21 CDJ39317.1 - 1.9 7.3 8.7 2.4 7.0 8.7 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Ctr PF04145.15 CDJ39317.1 - 2.1 8.9 5.2 2.4 8.8 5.2 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Peptidase_S15 PF02129.18 CDJ39317.1 - 2.4 7.7 10.3 2.6 7.6 10.3 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Neur_chan_memb PF02932.16 CDJ39317.1 - 2.8 7.9 8.7 3.1 7.8 8.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ39317.1 - 2.8 6.9 5.9 2.8 6.9 5.9 1.1 1 0 0 1 1 1 0 CLN3 protein Band_3_cyto PF07565.13 CDJ39317.1 - 2.9 7.6 8.4 3.3 7.5 8.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain EOS1 PF12326.8 CDJ39317.1 - 3.2 7.6 4.7 3.7 7.4 4.7 1.2 1 0 0 1 1 1 0 N-glycosylation protein V_ATPase_I PF01496.19 CDJ39317.1 - 3.3 5.5 10.6 3.6 5.4 10.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ39317.1 - 4.7 5.9 14.7 5.5 5.6 14.7 1.0 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ39317.1 - 5.1 7.0 30.8 5.5 6.9 30.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.6 CDJ39317.1 - 5.2 4.8 28.4 6.6 4.5 28.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Sin_N PF04801.13 CDJ39317.1 - 5.3 6.1 19.3 5.6 6.1 19.3 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region DUF1980 PF09323.10 CDJ39317.1 - 6 6.7 6.7 6.9 6.5 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PAT1 PF09770.9 CDJ39317.1 - 7.1 4.8 20.0 7.4 4.7 20.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MAJIN PF15077.6 CDJ39317.1 - 8.5 6.1 8.8 9.6 5.9 8.8 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein Eapp_C PF10238.9 CDJ39317.1 - 8.7 6.4 17.0 11 6.1 16.7 1.3 1 1 0 1 1 1 0 E2F-associated phosphoprotein GDP_Man_Dehyd PF16363.5 CDJ39319.1 - 1.7e-47 162.4 0.0 2.7e-31 109.2 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDJ39319.1 - 5.5e-47 160.3 0.0 1.4e-32 113.1 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDJ39319.1 - 3.9e-14 52.3 0.0 4.2e-08 32.5 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CDJ39319.1 - 9.2e-13 48.0 0.0 3.6e-05 23.0 0.0 3.5 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CDJ39319.1 - 4.9e-11 42.3 0.1 1.1e-06 28.0 0.0 2.2 1 1 1 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.6 CDJ39319.1 - 4.7e-09 36.4 0.2 1.7e-08 34.5 0.2 1.9 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CDJ39319.1 - 2.1e-07 31.0 0.6 5.6e-06 26.4 0.1 2.2 1 1 1 2 2 2 1 KR domain NAD_binding_4 PF07993.12 CDJ39319.1 - 0.00018 20.8 0.1 0.00082 18.6 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CDJ39319.1 - 0.00025 20.5 0.0 0.0009 18.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ39319.1 - 0.00043 19.9 0.1 0.0009 18.9 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ribosomal_60s PF00428.19 CDJ39319.1 - 0.0023 18.5 3.3 0.0067 17.0 3.3 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein Glyco_transf_4 PF13439.6 CDJ39319.1 - 0.013 15.5 0.1 0.27 11.2 0.0 2.4 3 0 0 3 3 3 0 Glycosyltransferase Family 4 3HCDH_N PF02737.18 CDJ39319.1 - 0.16 11.9 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F-box-like PF12937.7 CDJ39320.1 - 0.0078 16.1 1.0 0.0078 16.1 1.0 2.7 2 0 0 2 2 2 1 F-box-like Penaeidin PF05927.11 CDJ39320.1 - 0.024 15.4 1.5 0.024 15.4 1.5 3.3 3 0 0 3 3 3 0 Penaeidin DUF1645 PF07816.11 CDJ39320.1 - 0.68 10.5 12.2 0.12 13.0 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) DUF1635 PF07795.11 CDJ39320.1 - 1.1 9.1 5.9 0.72 9.7 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) SR-25 PF10500.9 CDJ39320.1 - 1.5 8.4 31.0 1.4 8.5 15.9 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4614 PF15391.6 CDJ39320.1 - 4.5 7.2 12.2 18 5.3 6.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) DUF1765 PF08578.10 CDJ39321.1 - 1.3e-12 48.3 0.0 2.2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) SUIM_assoc PF16619.5 CDJ39321.1 - 0.0037 17.3 15.7 0.44 10.7 0.1 3.7 3 0 0 3 3 3 3 Unstructured region C-term to UIM in Ataxin3 FliG_M PF14841.6 CDJ39322.1 - 0.0033 17.6 1.4 0.0033 17.6 1.4 1.1 1 0 0 1 1 1 1 FliG middle domain Sun2_CC2 PF18580.1 CDJ39322.1 - 0.024 14.9 1.4 0.027 14.7 1.4 1.1 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 zf-U1 PF06220.12 CDJ39324.1 - 1.7e-17 62.9 1.5 2.4e-17 62.4 1.5 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.7 CDJ39324.1 - 5.7 7.5 5.2 67 4.1 5.2 2.1 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ39324.1 - 6.4 7.2 5.7 0.63 10.4 1.3 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding VIT1 PF01988.19 CDJ39327.1 - 0.11 12.3 0.2 0.11 12.3 0.2 2.3 2 0 0 2 2 2 0 VIT family Gemini_BL1 PF00845.19 CDJ39327.1 - 0.48 10.0 1.9 1 8.9 1.9 1.5 1 0 0 1 1 1 0 Geminivirus BL1 movement protein SUIM_assoc PF16619.5 CDJ39327.1 - 1.1 9.4 30.8 0.27 11.3 0.6 4.8 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ39328.1 - 3.2e-05 23.1 39.5 0.00055 19.0 21.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ39328.1 - 0.0021 17.7 61.0 0.038 13.6 10.7 2.2 2 0 0 2 2 2 2 Spt20 family ASC PF00858.24 CDJ39328.1 - 0.028 13.4 0.8 0.033 13.2 0.8 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel EPL1 PF10513.9 CDJ39328.1 - 0.03 14.7 18.1 0.34 11.3 10.2 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like SpoIIP PF07454.11 CDJ39328.1 - 0.036 13.5 20.0 0.24 10.8 12.2 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Eapp_C PF10238.9 CDJ39328.1 - 0.039 14.0 19.7 0.32 11.1 11.0 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein MAT1 PF06391.13 CDJ39328.1 - 0.086 12.7 23.6 0.61 9.9 14.3 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF4770 PF15994.5 CDJ39328.1 - 0.23 11.7 23.2 1 9.6 14.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) FAM76 PF16046.5 CDJ39328.1 - 0.28 10.5 21.2 0.68 9.2 13.1 2.1 2 0 0 2 2 2 0 FAM76 protein MecA PF05389.12 CDJ39328.1 - 0.51 9.9 15.5 3.2 7.3 0.4 2.2 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Ferlin_C PF16165.5 CDJ39328.1 - 1.1 9.2 4.2 3.8 7.4 0.6 2.2 2 0 0 2 2 2 0 Ferlin C-terminus DUF5523 PF17661.1 CDJ39328.1 - 1.4 8.5 24.5 3 7.5 2.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) MMM1 PF10296.9 CDJ39328.1 - 1.5 7.8 13.8 2 7.4 7.3 2.1 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 FAM176 PF14851.6 CDJ39328.1 - 1.7 8.3 15.7 11 5.7 0.1 2.2 2 0 0 2 2 2 0 FAM176 family Dala_Dala_lig_N PF01820.21 CDJ39328.1 - 1.9 9.0 4.2 12 6.4 1.6 2.2 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus RPA43_OB PF17875.1 CDJ39328.1 - 2.1 9.0 16.2 8.4 7.0 0.5 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I TMEM51 PF15345.6 CDJ39328.1 - 2.2 8.1 31.9 0.22 11.4 17.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 DUF4471 PF14740.6 CDJ39328.1 - 2.2 7.4 13.3 2 7.6 7.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) TRAP_alpha PF03896.16 CDJ39328.1 - 2.3 7.3 10.8 1.9 7.6 4.7 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CTNNB1_binding PF08347.11 CDJ39328.1 - 2.5 8.3 14.5 6.6 6.9 0.6 2.2 2 0 0 2 2 2 0 N-terminal CTNNB1 binding Band_3_cyto PF07565.13 CDJ39328.1 - 2.5 7.8 20.3 5.6 6.7 0.5 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Sec62 PF03839.16 CDJ39328.1 - 2.8 7.4 16.2 7.5 6.0 9.7 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 DUF3807 PF12720.7 CDJ39328.1 - 3.3 8.0 32.7 1.4 9.2 17.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) eIF-3_zeta PF05091.12 CDJ39328.1 - 3.5 6.5 34.3 0.53 9.2 3.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4569 PF15133.6 CDJ39328.1 - 4.5 6.9 24.9 0.64 9.7 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) BSMAP PF12280.8 CDJ39328.1 - 5.8 7.1 16.7 9.7 6.3 0.4 2.2 2 0 0 2 2 2 0 Brain specific membrane anchored protein Spore_coat_CotO PF14153.6 CDJ39328.1 - 5.9 6.8 41.6 0.95 9.4 11.6 2.2 2 0 0 2 2 2 0 Spore coat protein CotO NPR3 PF03666.13 CDJ39328.1 - 6.4 5.4 19.6 5.1 5.8 12.8 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1644 PF07800.12 CDJ39328.1 - 6.9 6.7 13.2 15 5.6 7.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) DUF4834 PF16118.5 CDJ39328.1 - 8.6 7.4 34.9 1.2 10.1 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PPL5 PF18168.1 CDJ39328.1 - 8.8 5.5 16.6 7.3 5.8 9.3 2.1 2 0 0 2 2 2 0 Prim-pol family 5 TERB2 PF15101.6 CDJ39328.1 - 9 6.3 34.9 9.3 6.2 5.5 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 TFB6 PF17110.5 CDJ39328.1 - 9.2 6.0 15.9 7.6 6.3 0.1 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH SprA-related PF12118.8 CDJ39330.1 - 4.2e-05 22.9 36.6 5.9e-05 22.4 36.6 1.1 1 0 0 1 1 1 1 SprA-related family TFIIA PF03153.13 CDJ39330.1 - 0.00062 19.9 33.9 0.00082 19.5 33.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 CDJ39330.1 - 0.00093 19.6 14.1 0.0014 19.1 14.1 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like Raftlin PF15250.6 CDJ39330.1 - 0.0093 14.8 9.5 0.01 14.6 9.5 1.1 1 0 0 1 1 1 1 Raftlin Presenilin PF01080.17 CDJ39330.1 - 0.03 13.1 20.0 0.041 12.7 20.0 1.1 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 CDJ39330.1 - 0.044 13.3 16.0 0.059 12.9 16.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RR_TM4-6 PF06459.12 CDJ39330.1 - 0.047 13.5 18.0 0.073 12.9 18.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ39330.1 - 0.051 12.4 10.1 0.063 12.1 10.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter NPR3 PF03666.13 CDJ39330.1 - 0.054 12.3 13.2 0.077 11.8 13.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PTPRCAP PF15713.5 CDJ39330.1 - 0.065 13.5 17.8 0.15 12.4 17.8 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Band_3_cyto PF07565.13 CDJ39330.1 - 0.074 12.9 9.9 0.11 12.3 9.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CDC45 PF02724.14 CDJ39330.1 - 0.075 11.3 14.2 0.089 11.1 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 CDJ39330.1 - 0.075 12.5 12.5 0.13 11.8 12.5 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ39330.1 - 0.088 11.8 18.8 0.11 11.4 18.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 CDJ39330.1 - 0.17 10.9 15.9 0.21 10.6 15.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Velvet PF11754.8 CDJ39330.1 - 0.17 11.8 13.9 0.26 11.2 13.9 1.2 1 0 0 1 1 1 0 Velvet factor FAM60A PF15396.6 CDJ39330.1 - 0.18 11.8 11.3 0.27 11.2 11.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Gti1_Pac2 PF09729.9 CDJ39330.1 - 0.2 11.8 11.1 0.31 11.1 11.1 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2052 PF09747.9 CDJ39330.1 - 0.22 11.7 22.5 0.36 11.0 22.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF2828 PF11443.8 CDJ39330.1 - 0.23 9.5 15.0 0.29 9.2 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CobT PF06213.12 CDJ39330.1 - 0.28 10.5 30.1 0.4 10.0 30.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Hydin_ADK PF17213.3 CDJ39330.1 - 0.28 11.4 15.3 0.42 10.9 15.3 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Nop53 PF07767.11 CDJ39330.1 - 0.29 10.5 26.4 0.4 10.0 26.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CCSAP PF15748.5 CDJ39330.1 - 0.31 11.2 21.0 0.45 10.6 21.0 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Tim54 PF11711.8 CDJ39330.1 - 0.32 9.7 13.1 0.52 9.0 13.1 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sec62 PF03839.16 CDJ39330.1 - 0.38 10.2 11.9 0.51 9.8 11.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S64 PF08192.11 CDJ39330.1 - 0.43 9.0 11.5 0.52 8.7 11.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 BORG_CEP PF14957.6 CDJ39330.1 - 0.44 11.7 9.5 0.77 10.9 9.5 1.5 1 0 0 1 1 1 0 Cdc42 effector DUF4050 PF13259.6 CDJ39330.1 - 0.5 10.7 12.9 0.88 9.9 12.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Membralin PF09746.9 CDJ39330.1 - 0.82 8.6 8.0 1 8.3 8.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein AUX_IAA PF02309.16 CDJ39330.1 - 0.96 9.3 8.8 1.3 8.8 8.8 1.4 1 0 0 1 1 1 0 AUX/IAA family GREB1 PF15782.5 CDJ39330.1 - 0.97 6.5 17.4 1.1 6.2 17.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 CDJ39330.1 - 1 9.4 13.9 1.5 8.9 13.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 CDJ39330.1 - 1.2 7.5 4.1 1.3 7.4 4.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SWI-SNF_Ssr4 PF08549.10 CDJ39330.1 - 1.7 7.2 24.2 2.3 6.8 24.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) MDM10 PF12519.8 CDJ39330.1 - 1.8 7.3 12.1 2.3 7.0 12.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Ndc1_Nup PF09531.10 CDJ39330.1 - 2 7.0 13.6 2.3 6.8 13.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LMBR1 PF04791.16 CDJ39330.1 - 2.1 7.2 4.1 2.1 7.2 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein VIR_N PF15912.5 CDJ39330.1 - 4.1 6.9 13.0 6.4 6.3 13.0 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal MAJIN PF15077.6 CDJ39330.1 - 4.1 7.1 15.1 6.6 6.5 15.1 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein Peptidase_S15 PF02129.18 CDJ39330.1 - 4.1 6.9 11.3 5.9 6.4 11.3 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Paramyxo_ncap PF00973.19 CDJ39330.1 - 4.2 6.2 15.2 5.4 5.8 15.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Rtf2 PF04641.12 CDJ39330.1 - 5.6 6.2 22.0 9 5.6 22.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Otopetrin PF03189.13 CDJ39330.1 - 5.8 5.6 7.9 6.8 5.4 7.9 1.1 1 0 0 1 1 1 0 Otopetrin DDRGK PF09756.9 CDJ39330.1 - 6.6 6.3 31.9 12 5.4 31.9 1.4 1 0 0 1 1 1 0 DDRGK domain Asp-B-Hydro_N PF05279.11 CDJ39330.1 - 6.9 6.7 18.6 11 6.0 18.6 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FliP PF00813.20 CDJ39330.1 - 7.9 6.3 6.5 14 5.5 6.5 1.5 1 0 0 1 1 1 0 FliP family Prenyltrans PF00432.21 CDJ39331.1 - 8.7e-33 111.8 26.6 6.2e-10 38.7 0.0 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CDJ39331.1 - 6.9e-10 38.5 0.1 1.9e-05 23.9 0.0 3.8 1 1 3 4 4 4 3 Squalene-hopene cyclase N-terminal domain SPX PF03105.19 CDJ39331.1 - 0.0047 16.9 3.3 0.006 16.6 3.3 1.1 1 0 0 1 1 1 1 SPX domain TED_complement PF07678.14 CDJ39331.1 - 0.0064 15.6 0.1 0.14 11.1 0.1 2.1 2 0 0 2 2 2 1 A-macroglobulin TED domain MFS_1 PF07690.16 CDJ39332.1 - 1.4e-28 99.9 29.5 7.5e-24 84.3 8.6 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CDJ39332.1 - 0.017 14.0 10.2 0.066 12.1 10.2 1.9 1 1 0 1 1 1 0 MFS_1 like family CDC50 PF03381.15 CDJ39334.1 - 1.2e-60 205.4 0.0 1.8e-60 204.9 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1673 PF07895.11 CDJ39334.1 - 0.19 11.4 0.6 9.5 5.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF2275 PF10039.9 CDJ39334.1 - 0.21 11.7 0.0 15 5.6 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) EF-hand_8 PF13833.6 CDJ39335.1 - 0.0061 16.4 1.2 0.015 15.1 1.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 CDJ39335.1 - 0.0065 16.9 2.3 0.016 15.7 1.2 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ39335.1 - 0.027 14.4 1.6 0.027 14.4 1.6 2.4 2 0 0 2 2 2 0 EF-hand domain Vps4_C PF09336.10 CDJ39335.1 - 0.18 11.8 0.0 0.46 10.5 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain EF-hand_1 PF00036.32 CDJ39335.1 - 0.64 9.7 2.5 2.7 7.7 2.5 2.1 1 0 0 1 1 1 0 EF hand Mlo PF03094.15 CDJ39336.1 - 1.7e-06 26.7 3.6 1.7e-06 26.7 3.6 1.9 1 1 1 2 2 2 1 Mlo family Baculo_VP91_N PF08475.10 CDJ39336.1 - 0.014 15.1 0.7 0.014 15.1 0.7 1.4 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal UPF0182 PF03699.13 CDJ39336.1 - 0.63 8.1 5.1 0.72 7.9 5.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Sigma_reg_N PF13800.6 CDJ39336.1 - 8.5 6.7 8.2 8.4 6.8 0.8 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DFP PF04127.15 CDJ39337.1 - 1.2e-12 48.1 9.0 7.9e-09 35.6 0.0 4.3 4 0 0 4 4 4 3 DNA / pantothenate metabolism flavoprotein LCE6A PF15858.5 CDJ39337.1 - 0.094 13.5 0.1 0.094 13.5 0.1 2.9 4 0 0 4 4 4 0 Late cornified envelope protein 6A family Spt20 PF12090.8 CDJ39337.1 - 0.34 10.5 6.5 0.67 9.5 6.5 1.5 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ39337.1 - 1.7 8.6 15.5 1.2 9.1 8.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TPR_1 PF00515.28 CDJ39338.1 - 1.5e-11 43.6 10.1 1.8e-06 27.5 0.8 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ39338.1 - 5e-10 38.7 14.0 0.00022 21.1 0.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ39338.1 - 1.6e-05 25.1 7.3 0.00035 20.8 1.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ39338.1 - 0.00018 21.1 6.9 0.02 14.6 0.2 3.6 2 1 1 3 3 3 1 TPR repeat TFIIA PF03153.13 CDJ39338.1 - 0.00035 20.7 50.3 0.0048 17.0 22.3 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit TPR_17 PF13431.6 CDJ39338.1 - 0.0031 17.8 2.0 0.0093 16.3 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat DDHD PF02862.17 CDJ39338.1 - 0.0044 17.2 21.1 0.075 13.2 4.7 2.4 2 0 0 2 2 2 2 DDHD domain BUD22 PF09073.10 CDJ39338.1 - 0.0059 16.0 42.2 0.013 14.9 16.9 2.1 2 0 0 2 2 2 2 BUD22 TPR_8 PF13181.6 CDJ39338.1 - 0.01 16.0 6.2 0.14 12.4 0.4 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ39338.1 - 0.012 15.8 0.1 0.012 15.8 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5113 PF17140.4 CDJ39338.1 - 0.45 10.3 3.5 0.72 9.6 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5113) PAT1 PF09770.9 CDJ39338.1 - 2 6.6 46.1 1.4 7.1 19.3 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 UPF0565 PF10561.9 CDJ39338.1 - 2.8 7.1 15.0 0.33 10.1 3.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 eIF-3_zeta PF05091.12 CDJ39338.1 - 4.1 6.3 34.4 0.72 8.8 11.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDC27 PF09507.10 CDJ39338.1 - 4.2 6.7 43.0 2.6 7.4 13.3 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 FAM76 PF16046.5 CDJ39338.1 - 5.5 6.3 36.5 1.4 8.2 17.3 2.3 2 0 0 2 2 2 0 FAM76 protein Endostatin PF06482.11 CDJ39338.1 - 7 6.0 23.8 6.2 6.2 8.0 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin PTPA PF03095.15 CDJ39339.1 - 1.6e-97 326.6 0.0 1.9e-97 326.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MIP PF00230.20 CDJ39341.1 - 7.9e-15 55.2 30.9 4.9e-09 36.2 13.0 3.8 1 1 2 3 3 3 3 Major intrinsic protein DUF3948 PF13134.6 CDJ39341.1 - 5.8 6.7 8.5 40 4.0 1.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3948) AAA PF00004.29 CDJ39342.1 - 4.6e-43 146.8 0.0 1.1e-42 145.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ39342.1 - 8.6e-11 41.5 0.6 1.7e-10 40.5 0.6 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CDJ39342.1 - 2.3e-09 37.1 0.0 4.8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CDJ39342.1 - 1.7e-06 28.3 0.0 4.4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ39342.1 - 5.9e-06 26.6 0.0 0.0045 17.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDJ39342.1 - 1.7e-05 24.6 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CDJ39342.1 - 2.5e-05 23.6 0.0 4.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 CDJ39342.1 - 5.3e-05 23.7 1.1 0.00083 19.8 0.2 3.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.14 CDJ39342.1 - 0.00011 22.2 0.6 0.00049 20.1 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CDJ39342.1 - 0.0012 18.9 0.0 0.005 16.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDJ39342.1 - 0.0012 19.4 0.1 0.0038 17.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 CDJ39342.1 - 0.0017 17.6 0.1 0.49 9.5 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain IstB_IS21 PF01695.17 CDJ39342.1 - 0.002 17.9 0.0 0.0058 16.4 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 CDJ39342.1 - 0.0044 17.2 0.0 0.012 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 CDJ39342.1 - 0.0059 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 CDJ39342.1 - 0.007 16.6 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDJ39342.1 - 0.0087 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDJ39342.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CDJ39342.1 - 0.023 14.4 0.2 0.064 13.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CDJ39342.1 - 0.028 14.3 1.0 2 8.2 0.0 3.1 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 CDJ39342.1 - 0.033 14.0 0.1 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CDJ39342.1 - 0.049 13.1 0.1 0.15 11.5 0.1 1.8 2 0 0 2 2 1 0 PhoH-like protein AAA_25 PF13481.6 CDJ39342.1 - 0.053 13.1 0.3 0.27 10.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 CDJ39342.1 - 0.056 13.0 0.0 0.15 11.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 CDJ39342.1 - 0.079 12.7 0.2 0.27 10.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CDJ39342.1 - 0.079 12.9 0.2 0.69 9.8 0.0 2.4 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 CDJ39342.1 - 0.083 12.8 0.0 0.47 10.3 0.0 2.0 1 1 0 2 2 2 0 NACHT domain ATPase PF06745.13 CDJ39342.1 - 0.11 11.8 0.2 1.1 8.5 0.1 2.2 1 1 0 2 2 2 0 KaiC TsaE PF02367.17 CDJ39342.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prot_ATP_OB_N PF17758.1 CDJ39342.1 - 0.16 11.7 0.0 0.47 10.1 0.0 1.8 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain Parvo_NS1 PF01057.17 CDJ39342.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Ribosomal_L13 PF00572.18 CDJ39343.1 - 1.4e-32 112.6 0.3 2.2e-32 111.9 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L13 MFS_1 PF07690.16 CDJ39344.1 - 7.5e-09 35.0 13.5 7.5e-09 35.0 13.5 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4834 PF16118.5 CDJ39344.1 - 0.015 16.2 10.2 3.7 8.6 6.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) OATP PF03137.20 CDJ39344.1 - 0.017 13.5 9.2 0.17 10.1 0.0 3.1 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 CDJ39344.1 - 0.023 13.3 7.7 0.012 14.2 2.7 2.3 2 0 0 2 2 2 0 MFS/sugar transport protein Pex2_Pex12 PF04757.14 CDJ39344.1 - 0.06 12.9 0.0 0.06 12.9 0.0 1.7 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region BT1 PF03092.16 CDJ39344.1 - 0.099 10.8 0.0 0.099 10.8 0.0 2.7 3 0 0 3 3 3 0 BT1 family CTU2 PF10288.9 CDJ39344.1 - 2.7 8.3 10.9 17 5.7 5.7 3.3 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 TMEM51 PF15345.6 CDJ39344.1 - 3.3 7.5 22.4 0.97 9.2 0.9 2.8 2 0 0 2 2 2 0 Transmembrane protein 51 Connexin PF00029.19 CDJ39344.1 - 6.9 6.4 8.5 1.3e+02 2.2 4.8 3.2 3 0 0 3 3 3 0 Connexin FGAR-AT_N PF18076.1 CDJ39345.1 - 0.028 14.4 0.6 0.066 13.2 0.1 1.9 2 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase N-terminal XisH PF08814.10 CDJ39345.1 - 0.03 14.5 0.3 0.056 13.6 0.3 1.4 1 0 0 1 1 1 0 XisH protein Takusan PF04822.13 CDJ39345.1 - 0.16 11.9 0.3 0.16 11.9 0.3 2.0 2 0 0 2 2 2 0 Takusan MRP-S26 PF14943.6 CDJ39345.1 - 0.17 11.8 2.8 0.31 10.9 2.8 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Apt1 PF10351.9 CDJ39345.1 - 0.52 9.1 3.3 0.7 8.7 3.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF737 PF05300.11 CDJ39345.1 - 0.72 10.2 5.2 1.4 9.2 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Kri1 PF05178.12 CDJ39345.1 - 1.4 9.5 4.4 3.9 8.1 0.7 2.2 2 0 0 2 2 2 0 KRI1-like family Aida_N PF08910.10 CDJ39346.1 - 0.12 12.8 1.1 12 6.4 0.1 2.7 2 0 0 2 2 2 0 Aida N-terminus DUF1635 PF07795.11 CDJ39346.1 - 0.76 9.6 5.2 1.6 8.6 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Phage_Gp23 PF10669.9 CDJ39346.1 - 0.89 9.9 5.5 0.48 10.8 2.3 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) SR-25 PF10500.9 CDJ39346.1 - 1.3 8.6 20.6 0.07 12.7 11.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.13 CDJ39346.1 - 2.6 8.6 12.5 0.31 11.6 8.2 1.6 2 0 0 2 2 2 0 Secretin N-terminal domain PPTA PF01239.22 CDJ39347.1 - 7e-10 38.3 2.1 0.012 15.3 0.0 3.8 3 0 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat RskA PF10099.9 CDJ39347.1 - 0.0011 19.3 0.2 0.0011 19.3 0.2 5.6 3 2 1 4 4 4 2 Anti-sigma-K factor rskA DUF4207 PF13904.6 CDJ39347.1 - 0.0036 17.0 40.3 0.0036 17.0 40.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4207) EIF4E-T PF10477.9 CDJ39347.1 - 0.18 10.6 23.5 0.26 10.0 23.5 1.3 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E HNOBA PF07701.14 CDJ39347.1 - 0.83 9.0 12.0 0.33 10.4 0.1 2.4 2 0 0 2 2 2 0 Heme NO binding associated Connexin PF00029.19 CDJ39347.1 - 6.7 6.4 14.3 3.1 7.5 0.5 2.3 2 0 0 2 2 2 0 Connexin RPA43_OB PF17875.1 CDJ39347.1 - 9.2 6.9 17.4 2 9.0 3.9 2.9 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I Ribosomal_L14e PF01929.17 CDJ39348.1 - 5.5e-30 103.7 3.7 7.3e-30 103.3 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 ER_lumen_recept PF00810.18 CDJ39349.1 - 8e-24 85.1 5.2 1.9e-23 83.9 5.2 1.6 1 1 0 1 1 1 1 ER lumen protein retaining receptor DUF3810 PF12725.7 CDJ39349.1 - 1.2 8.4 6.4 1.3 8.3 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3810) EMP70 PF02990.16 CDJ39350.1 - 9.2e-183 608.6 4.9 9.2e-183 608.6 4.9 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 SUIM_assoc PF16619.5 CDJ39350.1 - 0.051 13.6 3.2 0.11 12.6 3.2 1.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LZ3wCH PF18517.1 CDJ39351.1 - 5.3e-07 29.6 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Leucine zipper with capping helix domain HalX PF08663.10 CDJ39351.1 - 0.019 15.2 2.3 0.088 13.1 0.6 2.3 2 1 0 2 2 2 0 HalX domain Spc7 PF08317.11 CDJ39351.1 - 0.032 13.1 0.7 0.052 12.4 0.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Mnd1 PF03962.15 CDJ39351.1 - 0.053 13.8 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Mnd1 HTH domain Methyltr_RsmB-F PF01189.17 CDJ39352.1 - 3.8e-31 108.3 0.0 2.5e-30 105.6 0.0 1.9 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 CDJ39352.1 - 4.5e-08 32.7 0.0 6.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CDJ39352.1 - 2.9e-07 30.4 0.0 6.2e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmF_N PF17125.5 CDJ39352.1 - 1.4e-06 28.7 0.0 2.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_25 PF13649.6 CDJ39352.1 - 3.5e-05 24.4 0.0 7.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 CDJ39352.1 - 0.0017 18.1 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 CDJ39352.1 - 0.0036 16.9 0.0 0.07 12.7 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 CDJ39352.1 - 0.013 15.3 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 CDJ39352.1 - 0.041 13.6 0.0 0.15 11.7 0.0 1.8 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 FtsJ PF01728.19 CDJ39352.1 - 0.099 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 CDJ39352.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Skp1_POZ PF03931.15 CDJ39353.1 - 8.2e-08 32.3 0.0 3.1e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Patatin PF01734.22 CDJ39354.1 - 1.7e-29 103.5 1.1 1.7e-29 103.5 1.1 3.8 4 1 0 4 4 4 1 Patatin-like phospholipase DUF4407 PF14362.6 CDJ39355.1 - 5.3 6.3 17.0 5.7 6.2 17.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 CDJ39355.1 - 8.5 6.7 20.2 9.5 6.6 20.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Amino_oxidase PF01593.24 CDJ39356.1 - 2.1e-09 37.2 0.6 4e-08 33.0 0.2 2.6 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ39356.1 - 1.5e-05 25.1 0.3 8.6e-05 22.7 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDJ39356.1 - 0.0036 17.0 0.1 0.097 12.2 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase MCRA PF06100.11 CDJ39356.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 MCRA family NAD_binding_9 PF13454.6 CDJ39356.1 - 0.069 13.1 0.1 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Myosin_head PF00063.21 CDJ39357.1 - 5e-174 580.2 0.0 4.6e-163 544.0 0.0 2.3 1 1 1 2 2 2 2 Myosin head (motor domain) MyTH4 PF00784.17 CDJ39357.1 - 3.4e-13 50.0 1.2 5.5e-12 46.1 0.0 3.5 3 1 0 3 3 3 1 MyTH4 domain IQ PF00612.27 CDJ39357.1 - 0.0008 19.0 0.8 0.0025 17.5 0.8 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_16 PF13191.6 CDJ39357.1 - 0.007 16.8 0.9 0.13 12.7 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 CDJ39357.1 - 0.025 13.8 0.3 0.057 12.7 0.3 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.7 CDJ39357.1 - 0.052 12.5 1.5 1.6 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.6 CDJ39357.1 - 0.054 13.8 2.7 0.29 11.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain Stk19 PF10494.9 CDJ39358.1 - 0.0099 15.6 0.0 0.025 14.2 0.0 1.6 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 Ribosomal_L1 PF00687.21 CDJ39359.1 - 1.1e-37 129.7 0.0 2.4e-37 128.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Acyl-CoA_dh_1 PF00441.24 CDJ39360.1 - 6.5e-25 88.1 4.4 9.3e-25 87.6 4.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ39360.1 - 1.2e-21 76.7 0.0 4.7e-21 74.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Peptidase_C97 PF05903.14 CDJ39360.1 - 4.8e-18 65.4 0.0 7.6e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Acyl-CoA_dh_2 PF08028.11 CDJ39360.1 - 2.5e-05 24.6 1.5 3.8e-05 24.0 1.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain LRAT PF04970.13 CDJ39360.1 - 0.032 14.5 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Rpr2 PF04032.16 CDJ39361.1 - 7.1e-06 26.2 0.0 7.1e-06 26.2 0.0 4.2 4 2 0 4 4 4 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain TPR_2 PF07719.17 CDJ39362.1 - 3e-05 23.8 3.7 0.065 13.4 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ39362.1 - 4.1e-05 23.2 2.7 0.034 14.0 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ39362.1 - 0.0037 17.7 2.9 0.01 16.3 0.4 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ39362.1 - 0.033 14.8 0.2 0.033 14.8 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ39362.1 - 0.034 14.4 1.6 10 6.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ39362.1 - 0.068 13.4 0.7 0.47 10.7 0.3 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDJ39362.1 - 0.081 13.2 8.2 0.39 11.0 0.6 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ39362.1 - 0.12 12.4 2.2 0.47 10.6 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ39362.1 - 0.26 12.2 2.7 2.6 9.1 0.4 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ39362.1 - 0.61 10.9 7.0 7.8 7.4 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ39362.1 - 1.1 9.1 3.4 60 3.4 0.0 3.6 4 0 0 4 4 4 0 TPR repeat MIT PF04212.18 CDJ39362.1 - 8.9 6.5 8.7 21 5.3 0.2 4.1 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain Nucleoporin_N PF08801.11 CDJ39363.1 - 0.13 11.0 0.0 0.41 9.3 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like AAA PF00004.29 CDJ39364.1 - 4.9e-15 56.1 0.0 1.1e-14 55.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CDJ39364.1 - 4.5e-14 52.6 0.0 8.4e-13 48.4 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 CDJ39364.1 - 6.4e-05 23.2 0.1 0.00024 21.4 0.1 2.0 2 0 0 2 2 2 1 AAA C-terminal domain AAA_22 PF13401.6 CDJ39364.1 - 7.2e-05 23.1 0.0 0.00098 19.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ39364.1 - 0.00018 21.3 0.1 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CDJ39364.1 - 0.00029 20.6 0.0 0.00079 19.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CDJ39364.1 - 0.00033 20.1 0.0 0.0014 18.0 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CDJ39364.1 - 0.00043 20.3 0.0 0.00076 19.5 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_19 PF13245.6 CDJ39364.1 - 0.00043 20.7 0.2 0.031 14.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDJ39364.1 - 0.00075 20.0 0.0 0.0015 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDJ39364.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CDJ39364.1 - 0.0011 18.9 0.0 0.0054 16.7 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CDJ39364.1 - 0.0013 19.1 0.1 0.0091 16.4 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 CDJ39364.1 - 0.0016 17.5 0.2 0.24 10.4 0.0 2.6 2 1 1 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 CDJ39364.1 - 0.0024 17.2 0.0 0.0035 16.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 CDJ39364.1 - 0.0024 17.9 0.1 0.019 15.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 CDJ39364.1 - 0.0027 17.5 0.2 0.025 14.4 0.0 2.4 1 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 CDJ39364.1 - 0.003 17.0 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 TIP49 PF06068.13 CDJ39364.1 - 0.0041 16.4 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CDJ39364.1 - 0.0052 17.0 0.0 0.016 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CDJ39364.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CDJ39364.1 - 0.018 15.3 0.0 0.12 12.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_2 PF07724.14 CDJ39364.1 - 0.027 14.6 0.0 0.068 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) DEAD PF00270.29 CDJ39364.1 - 0.045 13.5 0.0 10 5.9 0.0 2.3 1 1 0 2 2 2 0 DEAD/DEAH box helicase Zot PF05707.12 CDJ39364.1 - 0.069 12.8 0.0 0.2 11.3 0.0 1.8 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_7 PF12775.7 CDJ39364.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 CDJ39364.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-AN1 PF01428.16 CDJ39365.1 - 1.6e-09 37.7 7.7 2.8e-09 37.0 7.7 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CDJ39365.1 - 0.0028 18.0 5.1 0.0046 17.3 5.1 1.3 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain zf-ribbon_3 PF13248.6 CDJ39365.1 - 0.024 14.1 1.8 0.081 12.4 1.8 2.0 1 0 0 1 1 1 0 zinc-ribbon domain IBR PF01485.21 CDJ39365.1 - 0.11 12.8 8.7 0.21 11.8 8.7 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Zn_Tnp_IS1 PF03811.13 CDJ39365.1 - 2.4 8.0 7.7 0.17 11.6 2.4 1.9 2 0 0 2 2 2 0 InsA N-terminal domain GTP_EFTU PF00009.27 CDJ39366.1 - 3.1e-66 222.7 0.2 4.7e-66 222.0 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CDJ39366.1 - 4.9e-31 107.0 0.0 4.2e-30 104.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CDJ39366.1 - 4.1e-19 68.4 0.0 8.9e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CDJ39366.1 - 9.3e-15 54.5 0.0 2.5e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CDJ39366.1 - 8.6e-12 45.3 0.1 2.2e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ39366.1 - 4.2e-05 23.6 0.1 8.8e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 CDJ39366.1 - 0.023 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Shikimate_DH PF01488.20 CDJ39366.1 - 0.027 14.5 0.0 0.51 10.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SRPRB PF09439.10 CDJ39366.1 - 0.16 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Myosin_head PF00063.21 CDJ39367.1 - 4.3e-173 577.1 0.6 1.6e-136 456.3 0.1 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) AAA_16 PF13191.6 CDJ39367.1 - 0.011 16.1 0.0 0.032 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ39367.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab PF00006.25 CDJ39367.1 - 0.027 14.1 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 CDJ39367.1 - 0.048 13.9 0.0 0.18 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 CDJ39367.1 - 0.099 12.7 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 CDJ39367.1 - 0.12 12.8 0.0 0.49 10.8 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Ank_2 PF12796.7 CDJ39368.1 - 1.9e-26 92.4 0.0 6.1e-12 46.0 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ39368.1 - 3.5e-15 55.8 0.0 1.7e-05 25.0 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ39368.1 - 1.4e-14 54.3 0.1 1.1e-09 38.6 0.0 3.3 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CDJ39368.1 - 4.2e-12 45.9 0.1 1.5e-05 25.3 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CDJ39368.1 - 8.6e-11 41.1 0.1 0.0032 17.8 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat HrpE PF06188.12 CDJ39369.1 - 0.15 11.9 0.2 0.29 11.0 0.2 1.4 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Sigma70_r4_2 PF08281.12 CDJ39371.1 - 0.2 11.3 1.3 3.7 7.3 0.1 2.7 2 0 0 2 2 2 0 Sigma-70, region 4 RHD3 PF05879.12 CDJ39373.1 - 1.2e-107 361.0 0.0 1.5e-107 360.6 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 CDJ39373.1 - 0.00074 19.6 2.2 0.0013 18.8 0.3 2.3 2 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 CDJ39373.1 - 0.00087 19.4 0.0 0.0023 18.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.19 CDJ39373.1 - 0.03 13.6 0.2 0.078 12.2 0.2 1.7 1 1 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Septin PF00735.18 CDJ39373.1 - 0.037 13.3 1.4 0.044 13.1 0.1 1.7 2 0 0 2 2 2 0 Septin Tctex-1 PF03645.13 CDJ39373.1 - 0.13 12.5 0.3 0.42 10.9 0.3 1.8 1 0 0 1 1 1 0 Tctex-1 family AAA_24 PF13479.6 CDJ39373.1 - 0.14 11.9 0.2 6.2 6.5 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 CDJ39373.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain DUF445 PF04286.12 CDJ39373.1 - 0.33 10.7 4.4 0.14 12.0 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) AAA_28 PF13521.6 CDJ39373.1 - 0.46 10.7 4.0 0.58 10.4 0.1 3.0 3 1 0 3 3 3 0 AAA domain RHH_5 PF07878.11 CDJ39374.1 - 0.054 13.4 1.1 0.17 11.8 0.1 2.3 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 tRNA-synt_1c PF00749.21 CDJ39375.1 - 5.1e-105 350.8 0.0 6.6e-105 350.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CDJ39375.1 - 5.4e-36 124.1 0.1 2e-35 122.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 CDJ39375.1 - 4.3e-05 23.5 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ39375.1 - 0.0025 18.0 0.0 0.0065 16.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GDA1_CD39 PF01150.17 CDJ39375.1 - 0.13 10.9 0.2 0.19 10.4 0.2 1.2 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family FAD_oxidored PF12831.7 CDJ39376.1 - 0.017 14.5 1.3 0.022 14.1 1.3 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ39376.1 - 0.13 12.5 0.3 0.35 11.1 0.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TF_Zn_Ribbon PF08271.12 CDJ39377.1 - 0.0043 16.5 0.4 0.0093 15.5 0.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Spore_III_AB PF09548.10 CDJ39377.1 - 0.017 15.2 1.1 0.033 14.3 0.5 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RPA_interact_C PF14768.6 CDJ39377.1 - 0.073 13.6 1.1 0.15 12.7 0.5 1.9 2 0 0 2 2 2 0 Replication protein A interacting C-terminal Rad50_zn_hook PF04423.14 CDJ39377.1 - 1.6 8.7 5.1 19 5.2 0.1 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif Roc PF08477.13 CDJ39378.1 - 1.5e-05 25.2 0.0 0.067 13.4 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CDJ39378.1 - 0.00075 19.9 0.1 0.0014 19.1 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 CDJ39378.1 - 0.0075 15.9 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Zeta_toxin PF06414.12 CDJ39378.1 - 0.15 11.3 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin Apt1 PF10351.9 CDJ39380.1 - 0.34 9.7 4.0 0.52 9.1 4.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain MAP70 PF07058.11 CDJ39380.1 - 6 5.5 5.9 9.4 4.8 5.9 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 DUF3597 PF12200.8 CDJ39380.1 - 9.3 6.8 15.4 5.9 7.4 1.3 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3597) Glyco_hydro_52 PF03512.13 CDJ39381.1 - 0.026 13.5 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 FERM_M PF00373.18 CDJ39381.1 - 0.095 13.1 0.9 1.8 9.0 0.9 2.4 1 1 0 1 1 1 0 FERM central domain Adeno_PIX PF03955.14 CDJ39381.1 - 7.2 6.8 11.3 4.2 7.6 8.9 1.9 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Ribosomal_60s PF00428.19 CDJ39384.1 - 0.38 11.4 14.8 1.1 9.9 14.8 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Methyltransf_32 PF13679.6 CDJ39385.1 - 4.8 7.1 7.9 11 6.0 0.4 3.2 3 0 0 3 3 3 0 Methyltransferase domain Hemagglutinin PF00509.18 CDJ39386.1 - 0.023 13.1 1.3 0.033 12.6 1.3 1.2 1 0 0 1 1 1 0 Haemagglutinin DUF3584 PF12128.8 CDJ39386.1 - 0.069 10.7 21.0 0.098 10.2 21.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 CDJ39386.1 - 0.072 13.6 24.8 0.022 15.3 13.3 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4446 PF14584.6 CDJ39386.1 - 0.11 12.5 0.3 0.11 12.5 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) SPX PF03105.19 CDJ39386.1 - 0.14 12.0 13.5 0.19 11.6 13.5 1.1 1 0 0 1 1 1 0 SPX domain RAP1 PF07218.11 CDJ39386.1 - 0.54 8.5 4.0 0.64 8.2 4.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Plasmodium_Vir PF05795.11 CDJ39386.1 - 1 8.7 3.1 1.9 7.8 3.1 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Taxilin PF09728.9 CDJ39386.1 - 3.2 6.9 24.6 0.049 12.8 9.9 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Spc24 PF08286.11 CDJ39386.1 - 4.9 7.5 16.3 10 6.4 4.5 3.3 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Tmemb_cc2 PF10267.9 CDJ39386.1 - 5.2 6.1 17.0 9.3 5.3 16.5 1.7 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein TPPII_N PF12583.8 CDJ39386.1 - 5.9 7.5 14.3 6.3 7.4 12.1 1.9 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal IMP2_N PF18590.1 CDJ39387.1 - 2.6e-27 95.2 0.1 4e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 CDJ39387.1 - 4.4e-26 90.5 1.0 4.4e-26 90.5 1.0 1.9 2 0 0 2 2 2 1 Immune Mapped Protein 2 (IMP2) C-terminal domain Dehydratase_MU PF02288.15 CDJ39387.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Dehydratase medium subunit zf-C3HC4_3 PF13920.6 CDJ39389.1 - 1.4e-05 24.9 10.8 3e-05 23.8 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ39389.1 - 1.3 9.0 12.1 2.6 8.0 12.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 NTP_transf_4 PF13562.6 CDJ39389.1 - 1.8 8.8 3.6 3.2 7.9 0.2 2.3 2 0 0 2 2 2 0 Sugar nucleotidyl transferase Ribosomal_L39 PF00832.20 CDJ39391.1 - 6.6e-23 80.1 9.8 7.3e-23 79.9 9.8 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein K_channel_TID PF07941.11 CDJ39395.1 - 0.011 16.2 1.5 0.011 16.2 1.5 3.2 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Corona_nucleoca PF00937.18 CDJ39395.1 - 0.27 10.2 7.2 0.14 11.1 4.9 1.6 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DUF1645 PF07816.11 CDJ39395.1 - 0.42 11.2 9.5 0.87 10.1 9.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) DUF2052 PF09747.9 CDJ39396.1 - 0.47 10.6 18.8 0.49 10.5 18.8 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FAM76 PF16046.5 CDJ39396.1 - 0.73 9.1 15.9 0.75 9.1 15.9 1.0 1 0 0 1 1 1 0 FAM76 protein Paf1 PF03985.13 CDJ39396.1 - 1.6 7.6 20.0 1.8 7.5 20.0 1.0 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 CDJ39396.1 - 3.3 5.9 17.9 3.7 5.7 17.9 1.0 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 CDJ39396.1 - 3.3 8.0 17.3 4.4 7.6 17.3 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SpoIIP PF07454.11 CDJ39396.1 - 3.4 7.1 17.8 3.4 7.1 17.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Dynamin_N PF00350.23 CDJ39396.1 - 4.7 7.2 8.0 4.7 7.2 8.0 1.1 1 0 0 1 1 1 0 Dynamin family Presenilin PF01080.17 CDJ39396.1 - 6.6 5.4 20.8 6.9 5.3 20.8 1.0 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 CDJ39396.1 - 7.2 5.3 11.4 7.2 5.3 11.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Lin-8 PF03353.15 CDJ39396.1 - 7.3 6.1 19.3 7.2 6.1 19.3 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF913 PF06025.12 CDJ39396.1 - 7.5 5.4 14.1 7.4 5.4 14.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 CDJ39396.1 - 7.8 6.6 13.7 8.2 6.5 13.7 1.1 1 0 0 1 1 1 0 DDHD domain Sec62 PF03839.16 CDJ39396.1 - 8.4 5.8 14.7 9.2 5.7 14.7 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Pex14_N PF04695.13 CDJ39396.1 - 8.5 7.0 23.5 9.4 6.9 23.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tim54 PF11711.8 CDJ39396.1 - 8.5 5.0 17.0 9.3 4.9 17.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TRAP_alpha PF03896.16 CDJ39396.1 - 8.9 5.4 9.7 9.2 5.4 9.7 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Endostatin PF06482.11 CDJ39396.1 - 9.2 5.6 14.9 9.4 5.6 14.9 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin YABBY PF04690.13 CDJ39396.1 - 9.4 6.8 15.0 9.8 6.7 15.0 1.1 1 0 0 1 1 1 0 YABBY protein FAM176 PF14851.6 CDJ39396.1 - 9.5 5.9 17.2 11 5.7 17.2 1.1 1 0 0 1 1 1 0 FAM176 family MID_MedPIWI PF18296.1 CDJ39399.1 - 0.066 13.0 10.0 0.11 12.3 10.0 1.3 1 0 0 1 1 1 0 MID domain of medPIWI Spt20 PF12090.8 CDJ39399.1 - 0.067 12.8 28.6 0.019 14.6 23.6 2.1 2 0 0 2 2 2 0 Spt20 family CobT PF06213.12 CDJ39399.1 - 0.08 12.3 14.3 0.12 11.8 14.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HEV_ORF1 PF02444.16 CDJ39399.1 - 0.098 13.2 10.4 0.13 12.9 10.4 1.4 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) SelK_SelG PF10961.8 CDJ39399.1 - 0.14 12.8 4.8 0.61 10.7 0.4 2.5 1 1 1 2 2 2 0 Selenoprotein SelK_SelG Baculo_PP31 PF05311.11 CDJ39399.1 - 0.3 10.6 5.3 0.42 10.0 5.3 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Presenilin PF01080.17 CDJ39399.1 - 0.36 9.5 9.7 0.57 8.9 9.7 1.3 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 CDJ39399.1 - 0.38 10.8 11.7 0.68 9.9 11.7 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 eIF-3_zeta PF05091.12 CDJ39399.1 - 0.39 9.6 9.1 0.51 9.3 9.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ39399.1 - 0.8 7.6 10.0 0.99 7.2 10.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4471 PF14740.6 CDJ39399.1 - 0.8 8.9 8.8 1.2 8.3 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF4407 PF14362.6 CDJ39399.1 - 0.81 9.0 10.2 1 8.7 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.17 CDJ39399.1 - 0.83 9.8 7.4 1.2 9.2 7.4 1.3 1 0 0 1 1 1 0 DDHD domain RP-C_C PF11800.8 CDJ39399.1 - 1.1 9.3 11.2 1.8 8.6 11.2 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4746 PF15928.5 CDJ39399.1 - 1.4 8.3 6.9 1.8 8.0 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4175 PF13779.6 CDJ39399.1 - 1.4 6.7 32.0 1.9 6.3 32.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FAM222A PF15258.6 CDJ39399.1 - 1.9 7.5 17.5 2.1 7.3 17.5 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Neur_chan_memb PF02932.16 CDJ39399.1 - 2 8.4 9.1 3.7 7.6 9.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.6 CDJ39399.1 - 3.3 7.6 17.1 5.3 6.9 17.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO ALMT PF11744.8 CDJ39399.1 - 3.8 6.2 7.1 5.1 5.8 7.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 CDJ39399.1 - 4.1 7.3 31.6 0.35 10.8 26.8 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CLN3 PF02487.17 CDJ39399.1 - 4.7 6.1 8.7 7.5 5.5 8.7 1.2 1 0 0 1 1 1 0 CLN3 protein EB PF01683.18 CDJ39400.1 - 0.21 11.9 42.9 20 5.6 4.4 10.2 7 4 0 7 7 7 0 EB module FOG_N PF15888.5 CDJ39400.1 - 0.47 10.8 38.4 1.7 9.0 0.8 10.0 8 3 4 12 12 12 0 Folded gastrulation N-terminus 2-oxoacid_dh PF00198.23 CDJ39401.1 - 3.1e-68 229.7 0.6 6.5e-64 215.6 0.2 2.4 2 0 0 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CDJ39401.1 - 4.1e-16 58.6 0.1 6.8e-16 57.9 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CDJ39401.1 - 3.9e-05 23.4 0.0 0.018 14.8 0.0 3.0 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 CDJ39401.1 - 0.086 13.6 0.2 0.48 11.1 0.2 2.1 1 1 1 2 2 2 0 HlyD family secretion protein FA_desaturase PF00487.24 CDJ39401.1 - 5.1 6.8 5.4 4.8 6.9 3.9 1.6 1 1 1 2 2 2 0 Fatty acid desaturase Spt20 PF12090.8 CDJ39403.1 - 0.011 15.4 12.3 0.012 15.3 12.3 1.2 1 0 0 1 1 1 0 Spt20 family DUF4660 PF15559.6 CDJ39403.1 - 0.02 15.2 3.4 0.03 14.6 3.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4660) IU_nuc_hydro PF01156.19 CDJ39403.1 - 0.051 13.1 0.7 0.058 13.0 0.7 1.2 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase Phostensin_N PF13916.6 CDJ39403.1 - 0.079 13.3 6.1 3.1 8.2 5.9 2.5 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Suf PF05843.14 CDJ39403.1 - 0.088 12.8 5.8 0.13 12.2 5.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ39403.1 - 0.2 11.6 17.5 0.26 11.2 17.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PET10 PF17316.2 CDJ39403.1 - 0.21 11.1 0.1 0.27 10.7 0.1 1.1 1 0 0 1 1 1 0 Petite colonies protein 10 Presenilin PF01080.17 CDJ39403.1 - 2 7.1 5.1 2.2 6.9 5.1 1.1 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 CDJ39403.1 - 2.6 8.2 9.2 0.7 10.0 5.7 1.7 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF2890 PF11081.8 CDJ39405.1 - 0.0045 17.1 0.2 0.016 15.3 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2890) Dehydrin PF00257.19 CDJ39405.1 - 0.021 15.4 0.5 0.021 15.4 0.5 4.0 3 1 0 3 3 3 0 Dehydrin Adeno_PV PF03910.13 CDJ39405.1 - 1.1 7.9 9.2 2.4 6.8 9.2 1.7 1 0 0 1 1 1 0 Adenovirus minor core protein PV Herpes_pp85 PF04637.12 CDJ39405.1 - 3.7 5.9 4.5 6 5.2 4.5 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Herpes_UL35 PF04496.12 CDJ39405.1 - 6.7 7.1 11.9 0.52 10.6 5.6 2.5 2 1 0 2 2 2 0 Herpesvirus UL35 family Mob1_phocein PF03637.17 CDJ39406.1 - 0.005 16.9 0.0 0.46 10.5 0.0 2.2 2 0 0 2 2 2 2 Mob1/phocein family Robl_LC7 PF03259.17 CDJ39408.1 - 0.15 11.8 8.9 0.58 10.0 1.7 2.1 1 1 1 2 2 2 0 Roadblock/LC7 domain Tic110 PF16940.5 CDJ39408.1 - 3.2 6.1 8.4 3.5 6.0 8.4 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter His_Phos_1 PF00300.22 CDJ39410.1 - 6.6e-13 48.8 9.0 1.7e-09 37.6 5.3 4.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) HAT PF02184.16 CDJ39412.1 - 6.9e-05 22.7 0.4 0.0077 16.2 0.0 2.4 2 0 0 2 2 2 2 HAT (Half-A-TPR) repeat U3_assoc_6 PF08640.11 CDJ39412.1 - 0.0044 17.1 0.7 0.23 11.5 0.2 2.3 1 1 1 2 2 2 2 U3 small nucleolar RNA-associated protein 6 DUF812 PF05667.11 CDJ39413.1 - 1.7 7.4 65.7 1.3 7.8 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Lip_A_acyltrans PF03279.13 CDJ39414.1 - 0.042 13.0 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase DUF4179 PF13786.6 CDJ39414.1 - 0.093 13.2 0.3 11 6.5 0.4 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) Med15 PF09606.10 CDJ39414.1 - 1.1 7.9 54.6 1.4 7.5 54.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SARAF PF06682.12 CDJ39414.1 - 1.6 8.3 13.7 2.4 7.7 13.7 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PAT1 PF09770.9 CDJ39414.1 - 3.4 5.8 27.5 4.9 5.3 27.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ureide_permease PF07168.11 CDJ39414.1 - 4.1 6.0 5.9 1.3 7.7 0.2 2.2 2 0 0 2 2 2 0 Ureide permease MORN PF02493.20 CDJ39415.1 - 3e-14 52.0 8.1 5.9e-07 29.0 0.5 3.6 3 1 0 3 3 3 3 MORN repeat CHZ PF09649.10 CDJ39416.1 - 0.24 10.9 3.2 0.61 9.6 3.2 1.7 1 0 0 1 1 1 0 Histone chaperone domain CHZ HSD3 PF15244.6 CDJ39416.1 - 1.3 8.4 17.1 1.6 8.1 17.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Macoilin PF09726.9 CDJ39416.1 - 4.4 5.7 21.3 5.6 5.4 21.3 1.1 1 0 0 1 1 1 0 Macoilin family Band_3_cyto PF07565.13 CDJ39416.1 - 4.5 7.0 9.5 5.3 6.8 9.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Joubert PF15392.6 CDJ39416.1 - 4.7 6.8 20.7 5.6 6.6 20.7 1.0 1 0 0 1 1 1 0 Joubert syndrome-associated SLC12 PF03522.15 CDJ39416.1 - 4.7 6.1 11.0 5.1 6.0 11.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ39416.1 - 7.3 6.3 12.0 8.2 6.2 12.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5094 PF17015.5 CDJ39416.1 - 8.5 6.4 8.5 11 6.1 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) F-protein PF00469.20 CDJ39416.1 - 9 5.8 10.0 11 5.6 10.0 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF668 PF05003.12 CDJ39417.1 - 0.02 15.4 0.0 0.063 13.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF668) CCDC24 PF15669.5 CDJ39419.1 - 0.079 12.8 5.0 0.14 12.0 5.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family MMR1 PF08505.10 CDJ39419.1 - 0.53 10.5 5.4 0.67 10.2 5.4 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.13 CDJ39419.1 - 1.7 8.6 25.6 1.9 8.4 25.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 CDJ39419.1 - 4 6.5 13.7 4.5 6.4 13.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Pkinase PF00069.25 CDJ39421.1 - 5.3e-06 26.0 0.3 1.6e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain DUF2722 PF10846.8 CDJ39421.1 - 1.5 7.7 17.5 2.7 6.9 17.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2722) BNR_3 PF13859.6 CDJ39421.1 - 6 6.1 5.2 1.5 8.1 1.1 1.8 1 1 1 2 2 2 0 BNR repeat-like domain Hamartin PF04388.12 CDJ39421.1 - 6.7 5.3 13.2 5.1 5.6 12.0 1.3 1 1 0 1 1 1 0 Hamartin protein Kelch_5 PF13854.6 CDJ39422.1 - 2.1e-05 24.4 0.0 2.4e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Kelch motif Kelch_1 PF01344.25 CDJ39422.1 - 0.009 15.6 0.1 0.012 15.2 0.1 1.2 1 0 0 1 1 1 1 Kelch motif Kelch_3 PF13415.6 CDJ39422.1 - 0.036 14.4 0.2 4.5 7.7 0.0 2.0 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ39422.1 - 0.053 13.5 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Kelch motif Amino_oxidase PF01593.24 CDJ39424.1 - 0.00018 20.9 0.0 0.015 14.6 0.0 2.3 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase C_GCAxxG_C_C PF09719.10 CDJ39424.1 - 1 9.6 3.1 0.73 10.1 0.8 1.8 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Nucleoporin2 PF04096.14 CDJ39427.1 - 2.9e-14 53.4 0.0 4.7e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Cas_CT1975 PF09344.10 CDJ39427.1 - 0.0067 15.9 3.7 0.0092 15.5 3.7 1.1 1 0 0 1 1 1 1 CT1975-like protein DUF4179 PF13786.6 CDJ39427.1 - 0.092 13.2 2.4 10 6.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) SPX PF03105.19 CDJ39427.1 - 0.31 10.9 5.0 0.34 10.8 5.0 1.1 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 CDJ39427.1 - 1.5 7.4 10.8 1.9 7.1 10.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 CDJ39427.1 - 1.7 7.4 6.0 2.1 7.1 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SOG2 PF10428.9 CDJ39427.1 - 4.1 6.5 12.5 5.3 6.1 12.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Lipoprotein_2 PF00921.17 CDJ39427.1 - 6.4 6.2 11.4 0.18 11.3 4.7 1.7 2 0 0 2 2 2 0 Borrelia lipoprotein GREB1 PF15782.5 CDJ39427.1 - 8.7 3.3 10.2 10 3.1 10.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 CDJ39427.1 - 9.8 6.1 31.0 18 5.2 31.0 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Collagen PF01391.18 CDJ39428.1 - 0.00088 19.0 31.1 0.00088 19.0 31.1 3.6 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Pkinase_Tyr PF07714.17 CDJ39429.1 - 8.1e-10 38.4 0.0 1.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ39429.1 - 2.9e-07 30.1 0.1 1.1e-06 28.3 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Herpes_capsid PF06112.11 CDJ39429.1 - 0.0019 18.3 9.6 0.0019 18.3 9.6 2.3 1 1 1 2 2 2 1 Gammaherpesvirus capsid protein PAT1 PF09770.9 CDJ39429.1 - 7.1 4.8 29.5 8.7 4.5 29.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IPPT PF01715.17 CDJ39431.1 - 6.3e-27 94.9 0.0 9.5e-20 71.4 0.2 2.1 2 0 0 2 2 2 2 IPP transferase DUF4046 PF13255.6 CDJ39431.1 - 0.078 13.5 0.2 0.31 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4046) TPK_catalytic PF04263.16 CDJ39432.1 - 8.3e-08 32.3 0.0 1.8e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain Ketoacyl-synt_2 PF13723.6 CDJ39432.1 - 1.6 8.3 9.7 1.1 8.8 8.2 1.4 1 1 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain SUIM_assoc PF16619.5 CDJ39432.1 - 1.9 8.6 9.8 0.047 13.8 3.1 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RecO_C PF02565.15 CDJ39433.1 - 0.00051 19.9 0.2 0.0008 19.2 0.2 1.3 1 0 0 1 1 1 1 Recombination protein O C terminal Suf PF05843.14 CDJ39433.1 - 0.051 13.6 0.0 0.083 12.9 0.0 1.3 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) stn_TNFRSF12A PF12191.8 CDJ39434.1 - 0.0082 16.4 2.0 0.0082 16.4 2.0 2.6 2 1 1 3 3 3 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SR-25 PF10500.9 CDJ39434.1 - 0.65 9.6 51.0 0.077 12.6 4.2 3.4 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein AUX_IAA PF02309.16 CDJ39434.1 - 1.6 8.6 10.0 0.55 10.0 4.0 2.2 2 0 0 2 2 2 0 AUX/IAA family NST1 PF13945.6 CDJ39435.1 - 3.6 7.6 10.3 3.9 7.5 10.3 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator Mucin PF01456.17 CDJ39435.1 - 5.5 7.0 19.2 5.8 6.9 19.2 1.0 1 0 0 1 1 1 0 Mucin-like glycoprotein SNF2_N PF00176.23 CDJ39436.1 - 6e-09 35.1 0.2 1.9e-08 33.4 0.2 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_25 PF13481.6 CDJ39436.1 - 0.028 14.0 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDJ39436.1 - 0.15 12.3 0.1 0.26 11.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 CDJ39436.1 - 0.15 12.0 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit WD40 PF00400.32 CDJ39437.1 - 7.8e-08 32.9 17.1 0.3 12.0 0.0 7.6 7 1 0 7 7 7 5 WD domain, G-beta repeat BASP1 PF05466.12 CDJ39438.1 - 0.039 14.0 28.4 0.056 13.5 28.4 1.2 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) TFIIA PF03153.13 CDJ39438.1 - 2.9 7.8 8.9 3.7 7.5 8.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ39439.1 - 0.12 11.1 26.6 6.7 5.4 26.3 2.4 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 CDJ39439.1 - 0.19 11.8 16.1 18 5.3 17.6 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SOBP PF15279.6 CDJ39439.1 - 2.6 8.6 24.1 1.1 9.8 18.4 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein ALMT PF11744.8 CDJ39439.1 - 6.9 5.4 15.6 19 3.9 14.5 1.9 2 0 0 2 2 2 0 Aluminium activated malate transporter CD20 PF04103.15 CDJ39440.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.5 2 0 0 2 2 2 0 CD20-like family DUF979 PF06166.12 CDJ39440.1 - 1 8.4 3.9 2.4 7.2 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF979) Aminotran_5 PF00266.19 CDJ39441.1 - 1.5e-15 57.0 0.0 1.7e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DUF5106 PF17127.4 CDJ39441.1 - 0.12 12.7 0.2 0.22 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) ANAPC3 PF12895.7 CDJ39442.1 - 0.0013 19.0 0.3 0.0033 17.6 0.3 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CDJ39442.1 - 0.0022 18.4 1.9 0.0022 18.4 1.9 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat Sin_N PF04801.13 CDJ39442.1 - 0.0032 16.8 1.4 0.004 16.4 1.4 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region SAGA-Tad1 PF12767.7 CDJ39442.1 - 0.0038 17.0 1.2 0.0047 16.7 1.2 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TFIIA PF03153.13 CDJ39442.1 - 0.015 15.3 9.9 0.016 15.2 9.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HrpB1_HrpK PF09613.10 CDJ39442.1 - 0.042 13.5 1.0 0.71 9.5 0.4 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) SR-25 PF10500.9 CDJ39442.1 - 0.18 11.4 9.5 0.29 10.7 9.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SpoIIIAH PF12685.7 CDJ39442.1 - 0.28 11.0 3.7 0.36 10.6 3.7 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Ndc1_Nup PF09531.10 CDJ39442.1 - 1.5 7.4 4.8 1.8 7.1 4.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ39442.1 - 2 7.1 4.5 2.5 6.7 4.5 1.2 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 CDJ39442.1 - 8.4 5.9 7.4 12 5.4 7.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RskA PF10099.9 CDJ39443.1 - 0.014 15.7 6.0 0.015 15.6 6.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Zincin_1 PF06262.11 CDJ39443.1 - 0.084 13.0 0.0 0.15 12.2 0.0 1.6 1 1 0 1 1 1 0 Zincin-like metallopeptidase PCIF1_WW PF12237.8 CDJ39444.1 - 1.5e-18 67.0 0.8 4e-18 65.6 0.8 1.7 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain DUF4471 PF14740.6 CDJ39444.1 - 0.0051 16.1 6.0 0.21 10.8 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4471) Zip PF02535.22 CDJ39444.1 - 0.042 13.1 8.3 0.58 9.3 0.1 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4746 PF15928.5 CDJ39444.1 - 0.19 11.1 10.4 0.23 10.8 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) SRP-alpha_N PF04086.13 CDJ39444.1 - 0.5 10.3 32.1 0.072 13.0 2.2 3.3 3 0 0 3 3 3 0 Signal recognition particle, alpha subunit, N-terminal MecA PF05389.12 CDJ39444.1 - 0.57 9.8 19.7 0.8 9.3 0.7 2.6 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) EOS1 PF12326.8 CDJ39444.1 - 0.65 9.9 16.7 3.1 7.7 1.7 2.6 2 0 0 2 2 2 0 N-glycosylation protein Lin-8 PF03353.15 CDJ39444.1 - 1.7 8.1 43.7 0.41 10.2 2.9 4.1 4 0 0 4 4 4 0 Ras-mediated vulval-induction antagonist Otopetrin PF03189.13 CDJ39444.1 - 2.7 6.7 12.9 0.9 8.3 0.0 2.4 2 1 0 2 2 2 0 Otopetrin CDC45 PF02724.14 CDJ39444.1 - 4.3 5.5 21.9 3.1 6.0 5.9 2.4 2 0 0 2 2 2 0 CDC45-like protein Connexin PF00029.19 CDJ39444.1 - 8.3 6.1 20.7 1 9.0 1.6 2.5 2 0 0 2 2 2 0 Connexin PmbA_TldD PF01523.16 CDJ39446.1 - 0.017 15.0 3.0 0.022 14.6 3.0 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase LZ_Tnp_IS66 PF13007.7 CDJ39446.1 - 1.4 9.7 7.3 1.3 9.8 2.3 2.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain DUF5427 PF10310.9 CDJ39446.1 - 6.9 5.5 7.8 7.8 5.3 7.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) His_Phos_1 PF00300.22 CDJ39447.1 - 2.1e-28 99.4 7.8 7.9e-26 90.9 2.1 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) TFIIA PF03153.13 CDJ39447.1 - 0.044 13.8 7.5 0.03 14.3 1.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF305 PF03713.13 CDJ39447.1 - 1.8 8.7 11.2 0.47 10.6 4.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF305) CDK2AP PF09806.9 CDJ39447.1 - 4.1 7.4 18.6 1.7 8.7 9.4 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein SPX PF03105.19 CDJ39448.1 - 0.0021 18.1 34.0 0.066 13.1 6.1 2.3 2 0 0 2 2 2 2 SPX domain MID_MedPIWI PF18296.1 CDJ39448.1 - 0.0037 17.1 1.6 0.0037 17.1 1.6 3.6 2 1 0 2 2 2 1 MID domain of medPIWI RAP1 PF07218.11 CDJ39448.1 - 0.018 13.4 10.9 0.69 8.1 7.9 2.2 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Citrate_synt PF00285.21 CDJ39449.1 - 2.1e-58 198.2 0.1 1.9e-36 125.9 0.1 2.1 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain tRNA_edit PF04073.15 CDJ39450.1 - 4e-05 23.7 1.2 0.0053 16.8 1.0 2.8 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Tic110 PF16940.5 CDJ39450.1 - 0.11 10.9 4.0 0.13 10.7 4.0 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Pro-rich PF15240.6 CDJ39450.1 - 1.5 9.1 46.8 2.5 8.4 46.8 1.3 1 0 0 1 1 1 0 Proline-rich TMEM234 PF10639.9 CDJ39451.1 - 4.8e-25 87.9 0.3 5.6e-25 87.6 0.3 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 Androgen_recep PF02166.16 CDJ39451.1 - 2.5 6.8 6.1 2.8 6.7 6.1 1.0 1 0 0 1 1 1 0 Androgen receptor SUIM_assoc PF16619.5 CDJ39451.1 - 5.4 7.2 15.1 7.7 6.7 15.1 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ras PF00071.22 CDJ39452.1 - 1.5e-32 112.4 0.1 1.7e-32 112.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ39452.1 - 9.9e-25 87.1 0.0 1.1e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ39452.1 - 5.6e-08 32.4 0.0 6.2e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ39452.1 - 2.8e-05 24.2 0.0 3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ39452.1 - 0.017 14.7 0.0 0.24 10.9 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DAP3 PF10236.9 CDJ39452.1 - 0.029 13.5 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 CDJ39452.1 - 0.05 13.9 0.0 0.05 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDJ39452.1 - 0.086 12.5 0.0 0.097 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDJ39452.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ39452.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase Gtr1_RagA PF04670.12 CDJ39452.1 - 0.16 11.3 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 CDJ39452.1 - 0.21 11.1 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region TFIIA PF03153.13 CDJ39453.1 - 0.36 10.8 28.5 1.6 8.7 5.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Exo5 PF09810.9 CDJ39453.1 - 0.45 10.0 3.0 0.48 9.9 0.1 2.2 2 1 1 3 3 3 0 Exonuclease V - a 5' deoxyribonuclease DUF4148 PF13663.6 CDJ39453.1 - 0.7 10.1 23.1 1.1 9.5 4.8 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) TFIIA PF03153.13 CDJ39456.1 - 0.026 14.5 19.8 0.034 14.1 19.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Helicase_RecD PF05127.14 CDJ39456.1 - 0.043 13.7 1.5 0.074 12.9 1.5 1.4 1 0 0 1 1 1 0 Helicase Tachylectin PF14517.6 CDJ39456.1 - 0.046 13.3 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Tachylectin Polysacc_deac_2 PF04748.13 CDJ39456.1 - 0.11 11.7 3.2 0.086 12.0 0.9 1.9 1 1 1 2 2 2 0 Divergent polysaccharide deacetylase Sin_N PF04801.13 CDJ39456.1 - 0.16 11.1 13.0 0.23 10.6 13.0 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region DUF1840 PF08895.11 CDJ39456.1 - 0.37 11.1 6.9 0.07 13.5 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Comm PF15957.5 CDJ39456.1 - 1.1 9.6 3.2 2.4 8.5 3.2 1.5 1 1 0 1 1 1 0 Commissureless DUF2722 PF10846.8 CDJ39456.1 - 1.5 7.7 18.0 1.2 8.0 9.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ39456.1 - 1.7 7.3 4.8 2.2 7.0 4.8 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ39456.1 - 3 6.4 10.5 3.6 6.2 10.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NINJA_B PF16136.5 CDJ39456.1 - 4.1 7.8 10.6 7.5 7.0 2.1 2.4 2 0 0 2 2 2 0 Putative nuclear localisation signal RskA PF10099.9 CDJ39457.1 - 0.00092 19.5 21.5 0.013 15.8 14.8 2.3 1 1 0 2 2 2 2 Anti-sigma-K factor rskA AAA PF00004.29 CDJ39457.1 - 0.0034 17.8 0.0 0.051 14.0 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TamB PF04357.13 CDJ39457.1 - 0.067 12.4 0.8 0.15 11.2 0.0 1.8 1 1 1 2 2 2 0 TamB, inner membrane protein subunit of TAM complex DUF5563 PF17718.1 CDJ39457.1 - 0.24 10.9 2.4 0.45 10.0 2.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5563) Shadoo PF14999.6 CDJ39457.1 - 0.5 10.5 12.4 0.6 10.2 0.2 2.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Pex14_N PF04695.13 CDJ39457.1 - 9.3 6.9 20.5 3.9 8.1 8.2 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.9 CDJ39458.1 - 0.029 14.0 0.9 0.029 14.0 0.9 3.0 3 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein PIG-U PF06728.13 CDJ39458.1 - 0.078 12.0 1.9 0.67 8.9 0.0 2.4 1 1 1 2 2 2 0 GPI transamidase subunit PIG-U CCSAP PF15748.5 CDJ39458.1 - 3.1 7.9 14.6 2.6 8.2 4.5 2.6 2 1 0 2 2 2 0 Centriole, cilia and spindle-associated Orf78 PF06024.12 CDJ39458.1 - 7.9 6.8 6.3 7.1 7.0 0.2 3.3 3 1 1 4 4 4 0 Orf78 (ac78) SR-25 PF10500.9 CDJ39460.1 - 0.016 14.8 6.4 0.016 14.8 6.4 4.5 3 1 2 5 5 4 0 Nuclear RNA-splicing-associated protein CSG2 PF16965.5 CDJ39460.1 - 0.035 13.0 4.8 0.089 11.7 1.0 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator Connexin PF00029.19 CDJ39460.1 - 0.065 13.0 1.1 7.1 6.3 0.2 2.3 2 0 0 2 2 2 0 Connexin Orf78 PF06024.12 CDJ39460.1 - 0.094 13.0 4.6 2.9 8.3 0.3 2.9 2 0 0 2 2 2 0 Orf78 (ac78) DUF4457 PF14652.6 CDJ39460.1 - 0.12 11.6 3.7 0.89 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4457) DUF4518 PF15008.6 CDJ39460.1 - 0.65 9.1 9.9 0.24 10.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) EOS1 PF12326.8 CDJ39460.1 - 0.69 9.8 5.3 10 6.0 0.1 2.7 3 0 0 3 3 3 0 N-glycosylation protein BSMAP PF12280.8 CDJ39460.1 - 0.74 10.0 13.5 0.92 9.7 0.2 3.3 2 1 0 2 2 2 0 Brain specific membrane anchored protein V_ATPase_I PF01496.19 CDJ39460.1 - 1.1 7.0 6.3 4.4 5.1 0.6 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3405 PF11885.8 CDJ39460.1 - 1.2 7.6 5.6 1.9 7.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3405) DUF3408 PF11888.8 CDJ39460.1 - 1.5 9.0 12.8 0.99 9.5 2.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) CPSF73-100_C PF11718.8 CDJ39460.1 - 4.4 6.8 7.5 0.4 10.2 0.6 2.3 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Rsc14 PF08586.10 CDJ39460.1 - 5.4 7.9 9.3 16 6.3 0.5 2.6 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit DUF3464 PF11947.8 CDJ39460.1 - 8.8 6.1 14.8 10 5.9 0.6 3.8 4 0 0 4 4 4 0 Photosynthesis affected mutant 68 V_ATPase_I PF01496.19 CDJ39461.1 - 0.00047 18.2 5.9 0.0007 17.7 5.9 1.3 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TMEM154 PF15102.6 CDJ39461.1 - 0.0044 16.9 0.3 0.057 13.3 0.0 2.2 2 0 0 2 2 2 1 TMEM154 protein family DUF2615 PF11027.8 CDJ39461.1 - 0.013 15.6 7.7 0.069 13.3 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2615) OATP PF03137.20 CDJ39461.1 - 0.041 12.2 0.8 0.06 11.6 0.8 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Orf78 PF06024.12 CDJ39461.1 - 0.061 13.6 1.7 0.71 10.2 0.0 2.9 1 1 1 2 2 2 0 Orf78 (ac78) CLN3 PF02487.17 CDJ39461.1 - 0.087 11.9 1.1 0.12 11.3 1.1 1.4 1 0 0 1 1 1 0 CLN3 protein SCIMP PF15050.6 CDJ39461.1 - 0.18 12.2 1.0 0.34 11.4 1.0 1.5 1 0 0 1 1 1 0 SCIMP protein SR-25 PF10500.9 CDJ39461.1 - 0.69 9.5 16.5 1 8.9 4.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Beta-lactamase2 PF13354.6 CDJ39461.1 - 1.1 8.8 7.6 2.5 7.7 6.8 1.9 1 1 1 2 2 2 0 Beta-lactamase enzyme family FAM176 PF14851.6 CDJ39461.1 - 1.2 8.8 4.7 3.2 7.4 4.8 1.6 1 1 0 1 1 1 0 FAM176 family Peptidase_S46 PF10459.9 CDJ39461.1 - 4.6 5.7 11.0 6.4 5.3 11.0 1.2 1 0 0 1 1 1 0 Peptidase S46 RAP1 PF07218.11 CDJ39461.1 - 8.4 4.5 5.9 12 4.0 5.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 CDJ39462.1 - 1e-16 61.1 0.0 2e-07 30.6 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ39462.1 - 4.5e-06 26.1 0.0 0.00047 19.5 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase RskA PF10099.9 CDJ39462.1 - 0.0088 16.4 7.4 0.0088 16.4 7.4 3.3 2 2 1 3 3 3 1 Anti-sigma-K factor rskA APH PF01636.23 CDJ39462.1 - 1.4 8.8 16.1 0.04 13.8 2.4 3.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF755 PF05501.11 CDJ39463.1 - 0.013 15.7 12.3 0.021 15.1 12.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Spt20 PF12090.8 CDJ39463.1 - 0.089 12.4 6.8 0.11 12.1 6.8 1.1 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 CDJ39463.1 - 0.29 10.7 13.1 0.57 9.7 13.1 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 CDJ39463.1 - 6.7 4.9 6.2 9 4.4 6.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4692 PF15763.5 CDJ39464.1 - 0.019 15.5 2.1 0.019 15.5 2.1 3.0 3 0 0 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) DUF2407 PF10302.9 CDJ39464.1 - 0.26 11.8 0.0 0.26 11.8 0.0 4.0 3 1 1 4 4 4 0 DUF2407 ubiquitin-like domain Dehydrin PF00257.19 CDJ39465.1 - 0.017 15.7 2.3 0.017 15.7 2.3 4.1 2 1 2 4 4 4 0 Dehydrin Adeno_E4 PF05385.11 CDJ39465.1 - 0.15 12.2 0.6 0.27 11.3 0.6 1.3 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein PPL5 PF18168.1 CDJ39465.1 - 5.6 6.2 10.2 0.22 10.8 2.3 2.5 1 1 2 3 3 3 0 Prim-pol family 5 DUF1644 PF07800.12 CDJ39469.1 - 0.021 14.9 10.1 0.031 14.3 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) DUF3984 PF13136.6 CDJ39469.1 - 0.041 13.3 11.5 0.051 13.0 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) SelP_N PF04592.14 CDJ39469.1 - 0.27 10.6 16.2 0.31 10.4 16.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pex14_N PF04695.13 CDJ39469.1 - 0.9 10.2 19.9 1.1 9.8 19.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 CDJ39469.1 - 1.1 9.1 10.6 1 9.1 10.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Activator_LAG-3 PF11498.8 CDJ39469.1 - 1.3 7.9 40.3 1.5 7.7 40.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RCR PF12273.8 CDJ39469.1 - 1.7 9.3 12.5 2.1 9.0 12.5 1.1 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF3546 PF12066.8 CDJ39469.1 - 2 8.7 13.0 3.3 7.9 13.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3546) V_ATPase_I PF01496.19 CDJ39469.1 - 2.2 6.1 11.9 2.3 6.0 11.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tim54 PF11711.8 CDJ39469.1 - 3.1 6.5 10.4 3.6 6.3 10.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PAT1 PF09770.9 CDJ39469.1 - 3.6 5.7 24.6 3.5 5.8 24.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ39469.1 - 4 7.4 14.5 4.5 7.3 14.5 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ39469.1 - 5.9 6.8 33.1 6.2 6.7 33.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.10 CDJ39469.1 - 7.2 6.7 9.7 9 6.3 9.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sec62 PF03839.16 CDJ39469.1 - 9.5 5.7 11.0 11 5.5 11.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Mitoc_L55 PF09776.9 CDJ39470.1 - 0.096 12.4 1.4 0.34 10.6 1.4 2.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 MCR_alpha PF02249.17 CDJ39471.1 - 0.49 10.8 2.6 0.5 10.8 2.6 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain RskA PF10099.9 CDJ39471.1 - 2.6 8.3 17.1 3 8.1 17.1 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4681 PF15732.5 CDJ39472.1 - 0.13 12.6 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) PT PF04886.12 CDJ39472.1 - 2.2 7.9 34.0 2 8.0 11.0 3.9 3 1 0 3 3 3 0 PT repeat Cnd1 PF12717.7 CDJ39474.1 - 0.0012 18.9 0.1 0.015 15.4 0.0 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 SPX PF03105.19 CDJ39474.1 - 0.53 10.1 9.3 37 4.1 9.2 2.2 1 1 0 1 1 1 0 SPX domain Hepatitis_core PF00906.20 CDJ39474.1 - 1.7 8.2 6.4 3.7 7.0 6.4 1.5 1 0 0 1 1 1 0 Hepatitis core antigen SGIII PF15467.6 CDJ39474.1 - 9.1 5.4 6.3 1.7 7.8 1.0 1.9 1 1 1 2 2 2 0 Secretogranin-3 DUF755 PF05501.11 CDJ39476.1 - 0.013 15.8 12.4 0.013 15.8 12.4 6.1 6 0 0 6 6 6 0 Domain of unknown function (DUF755) Spt20 PF12090.8 CDJ39476.1 - 0.054 13.1 0.3 0.054 13.1 0.3 4.5 3 1 0 3 3 3 0 Spt20 family LMBR1 PF04791.16 CDJ39476.1 - 0.36 9.7 8.3 1.2 8.0 2.8 2.4 2 0 0 2 2 2 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 CDJ39476.1 - 1.9 6.3 13.8 0.35 8.7 8.0 2.2 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Radical_SAM_N PF08497.10 CDJ39476.1 - 7.3 5.7 7.3 17 4.5 7.3 1.5 1 0 0 1 1 1 0 Radical SAM N-terminal LCD1 PF09798.9 CDJ39476.1 - 7.9 4.9 17.1 0.93 7.9 12.1 1.8 2 0 0 2 2 2 0 DNA damage checkpoint protein GTP_EFTU PF00009.27 CDJ39477.1 - 1.1e-42 145.8 0.0 1.6e-41 142.0 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CDJ39477.1 - 5e-09 36.1 0.0 1.2e-07 31.7 0.0 2.4 1 1 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CDJ39477.1 - 9.3e-07 28.9 0.0 2.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CDJ39477.1 - 0.0019 18.3 0.1 0.0061 16.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 CDJ39477.1 - 0.052 12.9 0.0 0.052 12.9 0.0 2.8 5 0 0 5 5 5 0 AIG1 family Ras PF00071.22 CDJ39477.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Ras family DUF4366 PF14283.6 CDJ39477.1 - 0.31 11.1 1.1 1.5 8.8 1.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Hamartin PF04388.12 CDJ39479.1 - 3.4 6.2 9.3 1.7 7.2 7.6 1.4 1 1 0 1 1 1 0 Hamartin protein DUF4050 PF13259.6 CDJ39479.1 - 7.7 6.8 11.5 43 4.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) DUF4638 PF15472.6 CDJ39480.1 - 0.16 11.7 3.0 0.17 11.6 3.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) PARM PF17061.5 CDJ39480.1 - 0.52 10.4 8.8 0.63 10.1 8.8 1.1 1 0 0 1 1 1 0 PARM Lin-8 PF03353.15 CDJ39480.1 - 0.65 9.5 12.0 0.71 9.4 12.0 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NST1 PF13945.6 CDJ39480.1 - 2.1 8.4 12.9 2.7 8.1 12.9 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Presenilin PF01080.17 CDJ39480.1 - 4.1 6.1 9.7 4.4 6.0 9.7 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ39480.1 - 4.4 5.4 20.4 4.9 5.3 20.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ39480.1 - 6.9 6.7 7.1 7.4 6.6 7.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 CDJ39480.1 - 9.9 4.1 9.5 10 4.1 9.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF3_subunit PF08597.10 CDJ39481.1 - 0.007 16.3 9.4 0.007 16.3 9.4 2.5 1 1 2 3 3 3 1 Translation initiation factor eIF3 subunit MRP-S31 PF15433.6 CDJ39481.1 - 0.0078 15.9 11.3 0.0078 15.9 11.3 2.2 1 1 1 2 2 2 1 Mitochondrial 28S ribosomal protein S31 Sprouty PF05210.13 CDJ39481.1 - 0.0098 16.3 0.6 0.02 15.2 0.6 1.6 1 0 0 1 1 1 1 Sprouty protein (Spry) ComFB PF10719.9 CDJ39481.1 - 0.021 14.9 2.5 0.021 14.9 2.5 2.6 2 1 0 2 2 2 0 Late competence development protein ComFB SOBP PF15279.6 CDJ39481.1 - 0.21 12.2 18.7 0.3 11.6 18.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Rrn6 PF10214.9 CDJ39481.1 - 0.23 9.9 30.6 0.3 9.5 30.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SpoIIE PF07228.12 CDJ39481.1 - 0.69 9.8 4.3 0.22 11.4 1.2 1.7 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) SOG2 PF10428.9 CDJ39481.1 - 0.8 8.8 29.9 1 8.5 29.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein HTH_9 PF08221.11 CDJ39482.1 - 0.54 10.4 3.3 6.6 6.9 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain MTTB PF06253.11 CDJ39482.1 - 1.2 7.0 9.2 1.5 6.7 9.2 1.2 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) PP2C PF00481.21 CDJ39483.1 - 1e-47 163.0 0.1 6.7e-45 153.7 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Ribosomal_L18 PF17135.4 CDJ39483.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e zf-Tim10_DDP PF02953.15 CDJ39484.1 - 1.2e-16 60.1 1.4 1.4e-16 59.9 1.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DnaJ PF00226.31 CDJ39485.1 - 1.3e-22 79.7 0.3 2.3e-22 78.9 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 CDJ39485.1 - 2.7e-13 50.1 0.0 5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Med3 PF11593.8 CDJ39485.1 - 0.051 12.8 9.9 0.067 12.4 9.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Velvet PF11754.8 CDJ39486.1 - 0.00017 21.6 6.5 0.00017 21.6 6.5 10.5 6 2 0 7 7 7 3 Velvet factor zf-C3H2C3 PF17122.5 CDJ39486.1 - 0.0013 18.7 0.7 0.0058 16.6 0.7 2.2 1 0 0 1 1 1 1 Zinc-finger GPCR_chapero_1 PF11904.8 CDJ39486.1 - 0.036 13.5 0.1 0.036 13.5 0.1 5.2 5 1 0 5 5 5 0 GPCR-chaperone Vps8 PF12816.7 CDJ39486.1 - 0.63 9.5 0.0 0.63 9.5 0.0 3.5 4 0 0 4 4 4 0 Golgi CORVET complex core vacuolar protein 8 DUF4471 PF14740.6 CDJ39486.1 - 7.9 5.6 27.5 0.24 10.6 2.1 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4471) Peptidase_S8 PF00082.22 CDJ39488.1 - 6.6e-41 140.5 1.5 6.6e-41 140.5 1.5 3.0 3 1 1 4 4 4 1 Subtilase family RskA PF10099.9 CDJ39488.1 - 0.011 16.1 0.1 0.011 16.1 0.1 12.4 2 2 5 7 7 7 0 Anti-sigma-K factor rskA Cu-binding_MopE PF11617.8 CDJ39488.1 - 0.018 15.2 1.6 0.04 14.1 1.6 1.6 1 0 0 1 1 1 0 Putative metal-binding motif Orthopox_F8 PF05886.11 CDJ39488.1 - 0.22 11.7 0.1 0.22 11.7 0.1 6.0 5 0 0 5 5 5 0 Orthopoxvirus F8 protein AP2 PF00847.20 CDJ39489.1 - 2.4e-06 27.6 0.9 2.4e-06 27.6 0.9 4.0 3 0 0 3 3 3 1 AP2 domain DUF3682 PF12446.8 CDJ39489.1 - 0.0013 19.2 27.9 0.0013 19.2 27.9 16.3 10 5 4 14 14 14 1 Protein of unknown function (DUF3682) HECT PF00632.25 CDJ39490.1 - 1.5e-91 307.1 0.0 2.4e-91 306.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 CDJ39490.1 - 1.6e-14 54.1 0.0 1.6e-14 54.1 0.0 13.4 13 2 0 13 13 13 2 Domain of Unknown Function (DUF908) UBA PF00627.31 CDJ39490.1 - 7.3e-10 38.6 0.1 2.4e-09 36.9 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain UBM PF14377.6 CDJ39490.1 - 3.9e-09 35.6 1.9 3.9e-09 35.6 1.9 4.3 3 0 0 3 3 3 1 Ubiquitin binding region DUF913 PF06025.12 CDJ39490.1 - 5.3e-07 28.9 0.0 3.8e-08 32.7 0.0 12.0 12 3 1 13 13 13 2 Domain of Unknown Function (DUF913) Radical_SAM PF04055.21 CDJ39491.1 - 0.0013 19.1 0.0 0.012 16.0 0.0 2.4 2 1 0 2 2 2 1 Radical SAM superfamily HTH_1 PF00126.27 CDJ39491.1 - 0.14 12.1 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Pkinase_Tyr PF07714.17 CDJ39492.1 - 9e-10 38.3 0.0 2.2e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ39492.1 - 2.9e-09 36.7 0.0 5.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ39492.1 - 6.5e-05 22.4 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Syntaxin-6_N PF09177.11 CDJ39492.1 - 6.1 7.5 8.8 18 6.0 2.6 3.2 1 1 1 3 3 3 0 Syntaxin 6, N-terminal ATPgrasp_TupA PF14305.6 CDJ39494.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.0 1 0 0 1 1 1 0 TupA-like ATPgrasp CRAL_TRIO PF00650.20 CDJ39495.1 - 5.1e-24 84.8 0.0 3e-23 82.3 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO domain Ribosomal_L35p PF01632.19 CDJ39495.1 - 2.1e-08 34.6 5.3 7.4e-08 32.8 5.3 1.9 1 0 0 1 1 1 1 Ribosomal protein L35 CRAL_TRIO_2 PF13716.6 CDJ39495.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CDJ39496.1 - 1.7e-23 83.1 0.0 2.8e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ39496.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain GTP1_OBG PF01018.22 CDJ39497.1 - 1.4e-26 92.9 3.1 5.1e-25 87.9 3.1 2.4 1 1 0 1 1 1 1 GTP1/OBG GTP_EFTU PF00009.27 CDJ39497.1 - 1.5e-07 31.2 0.0 0.00096 18.7 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ39497.1 - 5.2e-07 29.7 0.0 8.4e-06 25.8 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ39497.1 - 0.0013 18.6 0.0 0.43 10.5 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase Arf PF00025.21 CDJ39497.1 - 0.0023 17.4 0.0 0.044 13.2 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.9 CDJ39497.1 - 0.0038 17.0 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.18 CDJ39497.1 - 0.0039 16.6 0.0 0.0086 15.5 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF3744 PF12558.8 CDJ39497.1 - 0.012 16.4 0.3 0.063 14.1 0.3 2.2 1 0 0 1 1 1 0 ATP-binding cassette cobalt transporter cobW PF02492.19 CDJ39497.1 - 0.013 15.1 0.0 4.4 6.9 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 CDJ39497.1 - 0.016 15.0 0.0 0.82 9.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 CDJ39497.1 - 0.082 12.0 0.0 9.5 5.3 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit Roc PF08477.13 CDJ39497.1 - 0.1 12.8 0.1 12 6.1 0.0 2.7 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CDJ39497.1 - 0.12 12.2 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mpt_N PF09176.11 CDJ39497.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Dynamin_N PF00350.23 CDJ39497.1 - 0.15 12.1 0.4 0.69 10.0 0.0 2.3 3 0 0 3 3 3 0 Dynamin family AAA_22 PF13401.6 CDJ39497.1 - 0.17 12.1 0.5 6.3 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CDJ39497.1 - 0.54 10.7 0.0 0.54 10.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain Spt20 PF12090.8 CDJ39497.1 - 0.78 9.3 12.5 0.061 12.9 4.3 2.4 2 0 0 2 2 2 0 Spt20 family IMS PF00817.20 CDJ39499.1 - 8.2e-39 133.0 0.3 2.9e-38 131.2 0.3 2.0 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CDJ39499.1 - 3e-12 47.3 0.9 6.5e-12 46.2 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CDJ39499.1 - 0.0002 21.5 0.0 0.00049 20.3 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.8 CDJ39499.1 - 0.0034 17.6 0.0 0.015 15.5 0.0 2.1 1 0 0 1 1 1 1 Pathogenicity locus mCpol PF18182.1 CDJ39499.1 - 0.051 13.9 0.6 0.27 11.6 0.1 2.4 3 0 0 3 3 3 0 minimal CRISPR polymerase domain SUIM_assoc PF16619.5 CDJ39499.1 - 0.071 13.2 0.1 0.071 13.2 0.1 5.9 4 2 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 TAN PF11640.8 CDJ39499.1 - 4.4 7.4 5.8 2.8 8.1 0.2 3.0 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair Folate_rec PF03024.14 CDJ39500.1 - 1.8e-14 54.0 13.1 2.5e-14 53.5 13.1 1.2 1 0 0 1 1 1 1 Folate receptor family Pinin_SDK_memA PF04696.13 CDJ39500.1 - 0.023 14.8 3.0 0.04 14.0 3.0 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region GPS2_interact PF15784.5 CDJ39500.1 - 0.085 13.3 3.9 0.17 12.4 3.9 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain MscS_TM PF12794.7 CDJ39500.1 - 4.2 6.1 4.9 0.45 9.3 0.5 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 MORN PF02493.20 CDJ39501.1 - 3.8e-12 45.3 14.8 7.8e-05 22.3 0.1 6.1 6 0 0 6 6 6 4 MORN repeat V_ATPase_I PF01496.19 CDJ39502.1 - 0.43 8.4 0.9 0.84 7.5 0.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pep1_7 PF17232.2 CDJ39502.1 - 3.7 8.1 5.7 2.4 8.7 0.2 2.8 2 0 0 2 2 2 0 Elicitor peptide 1-7 VirB8 PF04335.13 CDJ39504.1 - 0.21 11.4 0.2 0.21 11.4 0.2 2.6 2 0 0 2 2 2 0 VirB8 protein TMV_coat PF00721.21 CDJ39505.1 - 0.08 12.8 0.6 0.12 12.2 0.6 1.3 1 0 0 1 1 1 0 Virus coat protein (TMV like) Ribosomal_60s PF00428.19 CDJ39505.1 - 0.4 11.3 9.4 0.25 11.9 3.7 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein NDK PF00334.19 CDJ39506.1 - 0.0042 17.1 0.0 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 Nucleoside diphosphate kinase HDC PF02329.16 CDJ39506.1 - 0.18 10.8 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 Histidine carboxylase PI chain DUF2771 PF10969.8 CDJ39506.1 - 0.44 10.6 2.6 0.56 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2771) DUF2722 PF10846.8 CDJ39506.1 - 0.9 8.4 9.4 0.48 9.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Glyco_tran_WecB PF03808.13 CDJ39507.1 - 0.053 13.5 0.2 0.27 11.2 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family SUIM_assoc PF16619.5 CDJ39507.1 - 0.69 10.0 8.1 1.9 8.6 0.7 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 ATP-synt_Eps PF04627.13 CDJ39509.1 - 7.6e-16 57.8 0.1 1e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain RRM_1 PF00076.22 CDJ39510.1 - 2.3e-15 56.2 0.0 5.1e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 CDJ39510.1 - 1.4e-14 53.8 0.1 2.8e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 Surp module cwf21 PF08312.12 CDJ39510.1 - 1.9e-12 47.1 3.5 1.9e-12 47.1 3.5 2.5 2 0 0 2 2 2 1 cwf21 domain Phage_sheath_1 PF04984.14 CDJ39510.1 - 0.0043 16.9 0.6 0.0043 16.9 0.6 2.5 3 0 0 3 3 3 1 Phage tail sheath protein subtilisin-like domain CTK3 PF12243.8 CDJ39510.1 - 0.009 16.0 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Ku_C PF03730.14 CDJ39510.1 - 0.015 16.0 1.4 0.015 16.0 1.4 2.7 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Tubulin PF00091.25 CDJ39511.1 - 2.5e-31 109.4 0.0 4.5e-28 98.8 0.0 2.9 2 1 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 CDJ39511.1 - 0.019 14.2 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin like E1-E2_ATPase PF00122.20 CDJ39512.1 - 9e-43 145.9 1.5 9e-43 145.9 1.5 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ39512.1 - 1.2e-18 68.2 0.0 3e-18 66.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ39512.1 - 7.7e-05 22.7 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDJ39512.1 - 0.0018 18.1 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_11 PF13086.6 CDJ39512.1 - 0.94 9.2 0.0 0.94 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Cation_ATPase_N PF00690.26 CDJ39513.1 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus BOP1NT PF08145.12 CDJ39514.1 - 0.0078 16.2 0.2 0.014 15.3 0.2 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain PEP-utilisers_N PF05524.13 CDJ39514.1 - 0.14 12.4 3.0 0.15 12.3 1.0 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal EF-hand_7 PF13499.6 CDJ39515.1 - 1.2e-15 57.7 0.0 3.8e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ39515.1 - 4.2e-13 48.1 0.0 1.6e-05 24.5 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 CDJ39515.1 - 1.1e-12 46.5 0.0 1.3e-05 24.4 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 CDJ39515.1 - 6e-08 31.9 0.1 3.1e-05 23.2 0.0 2.8 2 1 1 3 3 3 2 EF hand EF-hand_8 PF13833.6 CDJ39515.1 - 1.5e-07 31.2 0.0 2.3e-05 24.1 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ39515.1 - 0.00039 20.7 0.0 0.00062 20.1 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 CDJ39515.1 - 0.05 13.7 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand LRR_4 PF12799.7 CDJ39521.1 - 2.8e-17 62.5 7.5 1.5e-05 25.2 0.0 5.2 2 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ39521.1 - 4.2e-15 55.2 1.3 5e-05 23.0 0.1 4.6 2 1 1 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 CDJ39521.1 - 4.3e-07 29.6 0.7 0.0032 17.0 0.1 2.4 1 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CDJ39521.1 - 8.6e-06 25.4 1.4 0.89 9.8 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 CDJ39521.1 - 0.0027 18.0 8.1 4.6 8.2 0.0 5.8 7 0 0 7 7 7 1 Leucine Rich Repeat Guanylate_cyc PF00211.20 CDJ39522.1 - 1.8e-17 63.6 0.2 3.3e-17 62.7 0.2 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Cor1 PF04803.12 CDJ39525.1 - 0.44 10.8 11.9 0.16 12.2 8.7 2.0 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region TPR_2 PF07719.17 CDJ39525.1 - 7.3 7.0 5.8 44 4.5 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat CpeT PF06206.11 CDJ39526.1 - 0.00016 21.7 0.0 0.00032 20.7 0.0 1.5 1 0 0 1 1 1 1 CpeT/CpcT family (DUF1001) NTP_transf_3 PF12804.7 CDJ39527.1 - 2.1e-13 50.9 0.0 5e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 CDJ39527.1 - 1.6e-12 47.6 0.0 2.7e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CDJ39527.1 - 0.00047 19.8 0.4 0.15 11.8 0.1 2.8 2 1 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 CDJ39527.1 - 0.001 18.1 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 CDJ39527.1 - 0.06 11.5 0.1 0.086 11.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 CDJ39527.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase CTP_transf_like PF01467.26 CDJ39528.1 - 0.0036 17.5 0.1 0.086 13.0 0.0 2.9 3 0 0 3 3 3 1 Cytidylyltransferase-like FAD_syn PF06574.12 CDJ39528.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 FAD synthetase Wbp11 PF09429.10 CDJ39528.1 - 0.21 12.0 0.1 0.21 12.0 0.1 1.9 2 0 0 2 2 2 0 WW domain binding protein 11 IMPDH PF00478.25 CDJ39529.1 - 1.9e-125 418.4 2.4 3.5e-125 417.6 2.4 1.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CDJ39529.1 - 1.5e-10 41.3 0.1 0.001 19.5 0.0 2.7 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 CDJ39529.1 - 2.1e-10 40.1 3.4 4e-10 39.3 1.7 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 CDJ39529.1 - 2.3e-10 40.4 8.6 1.3e-06 28.0 4.4 3.1 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 CDJ39529.1 - 1e-05 25.1 2.9 7.2e-05 22.4 2.9 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 CDJ39529.1 - 0.0016 17.8 3.0 0.0024 17.3 1.8 1.8 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 CDJ39529.1 - 0.0021 17.3 1.8 0.1 11.8 1.8 2.8 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase G3P_antiterm PF04309.12 CDJ39529.1 - 0.018 14.4 0.8 0.49 9.8 0.1 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator DHO_dh PF01180.21 CDJ39529.1 - 0.041 13.1 1.3 0.12 11.5 1.3 1.8 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 CDJ39529.1 - 0.065 12.6 3.2 0.5 9.7 2.7 2.5 2 1 0 2 2 2 0 Thiamine monophosphate synthase NAD_binding_7 PF13241.6 CDJ39529.1 - 0.24 11.9 1.4 24 5.4 0.1 2.6 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF5455 PF17537.2 CDJ39530.1 - 0.11 12.9 4.1 1.8 9.0 2.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5455) Exo_endo_phos PF03372.23 CDJ39532.1 - 0.00024 20.7 0.0 0.0012 18.5 0.0 2.1 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 CDJ39533.1 - 2.9e-33 115.3 0.0 4.4e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ39533.1 - 5.6e-22 78.3 0.0 9.2e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ39533.1 - 0.00099 19.1 1.4 0.001 19.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family MTS PF05175.14 CDJ39534.1 - 6.8e-09 35.5 0.3 0.00011 21.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltrans_SAM PF10672.9 CDJ39534.1 - 7.3e-07 28.6 0.0 6.1e-05 22.3 0.1 2.2 2 0 0 2 2 2 1 S-adenosylmethionine-dependent methyltransferase Methyltransf_31 PF13847.6 CDJ39534.1 - 5.9e-06 26.2 0.0 6.3e-05 22.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ39534.1 - 1.6e-05 25.5 0.6 0.0015 19.2 0.2 2.7 1 1 1 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CDJ39534.1 - 3.2e-05 23.7 0.6 0.037 13.7 0.6 2.3 1 1 0 1 1 1 1 Conserved hypothetical protein 95 PUA_3 PF17785.1 CDJ39534.1 - 0.00015 21.5 0.0 0.00051 19.8 0.0 1.9 1 1 0 1 1 1 1 PUA-like domain PrmA PF06325.13 CDJ39534.1 - 0.00025 20.5 0.0 0.00048 19.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 CDJ39534.1 - 0.00027 20.9 0.0 0.00049 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ39534.1 - 0.0088 16.7 1.0 0.19 12.4 0.1 2.9 2 1 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.19 CDJ39534.1 - 0.015 15.4 0.1 0.032 14.4 0.1 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Met_10 PF02475.16 CDJ39534.1 - 0.017 14.9 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.18 CDJ39534.1 - 0.043 13.5 0.0 0.1 12.2 0.0 1.5 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 CDJ39534.1 - 0.05 12.9 0.0 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DSPn PF14671.6 CDJ39535.1 - 3.6e-43 147.4 0.3 9.8e-43 146.0 0.4 1.7 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CDJ39535.1 - 1.1e-08 34.9 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ39535.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDJ39535.1 - 0.0029 17.7 0.0 0.005 17.0 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CDJ39535.1 - 0.14 12.1 0.1 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family RskA PF10099.9 CDJ39538.1 - 0.048 13.9 0.1 0.048 13.9 0.1 3.2 1 1 2 3 3 3 0 Anti-sigma-K factor rskA DNA_pol_A_exo1 PF01612.20 CDJ39538.1 - 0.072 12.8 0.1 10 5.8 0.0 2.2 2 0 0 2 2 2 0 3'-5' exonuclease PGA2 PF07543.12 CDJ39538.1 - 0.18 11.8 1.1 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 GCV_H PF01597.19 CDJ39539.1 - 0.00028 20.8 0.0 0.00067 19.5 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein RskA PF10099.9 CDJ39539.1 - 0.0011 19.4 11.8 0.0011 19.4 11.8 4.6 1 1 2 3 3 3 1 Anti-sigma-K factor rskA PPR_3 PF13812.6 CDJ39540.1 - 0.00072 19.6 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 CDJ39540.1 - 0.071 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 PPR repeat family SUIM_assoc PF16619.5 CDJ39540.1 - 0.49 10.5 14.5 3.8 7.7 0.7 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FliD_N PF02465.18 CDJ39540.1 - 0.59 10.9 4.3 2.3 9.0 0.1 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Spt20 PF12090.8 CDJ39540.1 - 2.2 7.8 8.9 8.8 5.9 3.1 2.1 2 0 0 2 2 2 0 Spt20 family Clat_adaptor_s PF01217.20 CDJ39541.1 - 1.4e-44 151.4 1.1 2.2e-42 144.3 1.1 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain zf-C3HC4_2 PF13923.6 CDJ39543.1 - 1.7e-09 37.4 10.2 1.7e-09 37.4 10.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ39543.1 - 2e-07 30.7 10.3 2e-07 30.7 10.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ39543.1 - 4.2e-07 30.2 9.7 4.2e-07 30.2 9.7 2.7 3 0 0 3 3 2 1 Ring finger domain LON_substr_bdg PF02190.16 CDJ39543.1 - 4.3e-07 30.0 0.1 1.2e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain U-box PF04564.15 CDJ39543.1 - 2.1e-06 27.8 4.2 2.5e-06 27.5 0.2 2.3 2 0 0 2 2 2 1 U-box domain zf-RING_UBOX PF13445.6 CDJ39543.1 - 4.1e-06 26.7 11.0 4.1e-06 26.7 11.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ39543.1 - 9e-06 25.5 10.2 9e-06 25.5 10.2 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ39543.1 - 4e-05 23.7 12.3 4e-05 23.7 12.3 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDJ39543.1 - 7.4e-05 22.6 8.3 7.4e-05 22.6 8.3 2.5 2 1 1 3 3 2 1 zinc-RING finger domain RskA PF10099.9 CDJ39543.1 - 0.00096 19.5 0.0 0.00096 19.5 0.0 4.6 3 2 0 4 4 2 1 Anti-sigma-K factor rskA zf-rbx1 PF12678.7 CDJ39543.1 - 0.0018 18.5 7.6 0.0018 18.5 7.6 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CDJ39543.1 - 0.0089 15.9 12.1 0.14 12.1 12.2 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 DUF3043 PF11241.8 CDJ39543.1 - 0.013 15.5 0.2 0.013 15.5 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) K_channel_TID PF07941.11 CDJ39543.1 - 0.014 15.8 6.1 0.014 15.8 6.1 8.0 6 2 1 7 7 2 0 Potassium channel Kv1.4 tandem inactivation domain zf-RING_10 PF16685.5 CDJ39543.1 - 0.018 15.2 8.6 0.053 13.7 8.6 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 Spt20 PF12090.8 CDJ39543.1 - 0.021 14.4 37.2 0.58 9.7 6.8 3.3 3 0 0 3 3 3 0 Spt20 family Hamartin PF04388.12 CDJ39543.1 - 1.2 7.7 9.0 0.29 9.8 2.4 2.0 2 0 0 2 2 2 0 Hamartin protein zf-RING_6 PF14835.6 CDJ39543.1 - 1.4 8.8 7.0 3.8 7.5 7.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein EIF4E-T PF10477.9 CDJ39543.1 - 2.2 7.0 16.3 0.55 9.0 3.9 2.1 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF2722 PF10846.8 CDJ39543.1 - 2.3 7.1 30.3 1.4 7.8 11.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) OmpH PF03938.14 CDJ39543.1 - 2.7 8.3 43.6 2.2 8.6 6.6 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Saw1 PF11561.8 CDJ39544.1 - 1.3 8.5 8.9 1.7 8.1 8.9 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 DUF4407 PF14362.6 CDJ39544.1 - 2.8 7.2 8.1 3.6 6.9 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 CDJ39544.1 - 4.2 6.0 7.2 5.2 5.7 7.2 1.1 1 0 0 1 1 1 0 Presenilin Hydin_ADK PF17213.3 CDJ39544.1 - 5.9 7.1 6.8 11 6.3 6.8 1.5 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain MMR1 PF08505.10 CDJ39548.1 - 0.13 12.6 22.9 0.22 11.8 22.9 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Lin-8 PF03353.15 CDJ39548.1 - 0.38 10.3 19.4 0.53 9.8 19.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SpoIIP PF07454.11 CDJ39548.1 - 0.47 9.9 9.5 0.61 9.5 9.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ39548.1 - 0.61 9.0 18.8 0.78 8.7 18.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NEMP PF10225.9 CDJ39548.1 - 1.2 8.7 7.3 1.9 8.1 7.3 1.2 1 0 0 1 1 1 0 NEMP family Macoilin PF09726.9 CDJ39548.1 - 1.8 7.0 23.9 2.7 6.4 23.9 1.2 1 0 0 1 1 1 0 Macoilin family Neur_chan_memb PF02932.16 CDJ39548.1 - 3.3 7.7 13.6 5.2 7.1 13.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ39548.1 - 5.1 6.8 15.7 6.8 6.4 15.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Miga PF10265.9 CDJ39548.1 - 6.9 5.5 17.2 11 4.9 17.2 1.2 1 0 0 1 1 1 0 Mitoguardin BORG_CEP PF14957.6 CDJ39548.1 - 8.9 7.5 15.6 2.7 9.1 12.7 1.8 2 0 0 2 2 2 0 Cdc42 effector LMBR1 PF04791.16 CDJ39548.1 - 9.2 5.0 6.2 11 4.8 6.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SUIM_assoc PF16619.5 CDJ39550.1 - 3.9 7.6 12.4 4.9 7.3 12.4 1.5 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 GREB1 PF15782.5 CDJ39552.1 - 0.75 6.8 6.6 1 6.4 6.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1645 PF07816.11 CDJ39552.1 - 0.8 10.2 20.0 1.7 9.1 5.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) SR-25 PF10500.9 CDJ39552.1 - 0.84 9.2 38.7 0.091 12.4 11.8 2.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein HTH_23 PF13384.6 CDJ39553.1 - 0.03 14.1 0.5 0.081 12.7 0.1 2.0 2 1 0 2 2 2 0 Homeodomain-like domain Lin-8 PF03353.15 CDJ39553.1 - 0.051 13.1 4.9 0.061 12.9 4.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spt20 PF12090.8 CDJ39553.1 - 0.072 12.7 11.0 0.096 12.3 11.0 1.2 1 0 0 1 1 1 0 Spt20 family MarR PF01047.22 CDJ39553.1 - 0.099 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 MarR family TFIIA PF03153.13 CDJ39553.1 - 0.26 11.3 12.0 0.28 11.1 12.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ39553.1 - 0.34 9.8 10.9 0.46 9.4 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ39553.1 - 0.45 9.2 2.9 0.55 8.9 2.9 1.1 1 0 0 1 1 1 0 Presenilin Conotoxin PF02950.17 CDJ39553.1 - 3 8.9 6.0 1.2 10.2 3.1 1.7 1 1 1 2 2 2 0 Conotoxin Pkinase PF00069.25 CDJ39554.1 - 0.00029 20.3 0.0 0.0003 20.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain IPTL-CTERM PF18203.1 CDJ39554.1 - 0.051 13.5 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 IPTL-CTERM motif PseudoU_synth_2 PF00849.22 CDJ39555.1 - 7.8e-05 22.8 3.3 7.8e-05 22.8 3.3 3.0 2 1 0 3 3 3 1 RNA pseudouridylate synthase TFIIA PF03153.13 CDJ39556.1 - 4.5 7.2 12.0 7.3 6.5 12.0 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AhpC-TSA PF00578.21 CDJ39557.1 - 1.9e-32 111.8 0.0 2.3e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ39557.1 - 1.7e-14 53.7 0.0 2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDJ39557.1 - 4.9e-12 45.5 0.0 1.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF5555 PF17710.1 CDJ39557.1 - 0.0084 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5555) TPPK_C PF12555.8 CDJ39558.1 - 0.047 13.7 1.5 0.15 12.1 0.4 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Arf PF00025.21 CDJ39560.1 - 3.8e-23 81.8 0.0 7.5e-23 80.9 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDJ39560.1 - 7.4e-14 52.0 0.9 4e-13 49.6 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDJ39560.1 - 5.3e-08 32.5 0.2 1.3e-07 31.2 0.2 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CDJ39560.1 - 3e-07 30.2 0.0 6.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CDJ39560.1 - 0.0003 20.1 13.6 0.0036 16.5 0.6 3.1 2 1 1 3 3 3 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CDJ39560.1 - 0.0079 16.3 0.1 0.046 13.8 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 CDJ39560.1 - 0.033 13.8 0.0 0.097 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.11 CDJ39560.1 - 0.035 12.6 15.7 0.044 12.3 15.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Utp14 PF04615.13 CDJ39560.1 - 0.08 11.5 25.4 0.11 11.0 25.4 1.1 1 0 0 1 1 1 0 Utp14 protein NB-ARC PF00931.22 CDJ39560.1 - 0.091 11.9 0.0 0.091 11.9 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain DUF4746 PF15928.5 CDJ39560.1 - 0.1 12.0 10.4 0.17 11.3 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AAA_18 PF13238.6 CDJ39560.1 - 0.15 12.6 0.0 0.15 12.6 0.0 2.8 2 1 0 2 2 1 0 AAA domain PAT1 PF09770.9 CDJ39560.1 - 0.19 10.0 25.3 0.23 9.7 25.3 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SRP54 PF00448.22 CDJ39560.1 - 0.19 11.3 0.0 0.19 11.3 0.0 3.1 2 1 2 4 4 3 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 CDJ39560.1 - 0.2 11.6 0.0 0.53 10.2 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CDJ39560.1 - 0.22 11.2 0.0 0.22 11.2 0.0 2.3 2 1 0 2 2 1 0 AAA domain AAA_33 PF13671.6 CDJ39560.1 - 0.44 10.7 0.0 0.44 10.7 0.0 3.1 2 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CDJ39560.1 - 0.65 10.5 8.8 0.73 10.4 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Spore_coat_CotO PF14153.6 CDJ39560.1 - 1.7 8.6 24.1 3.3 7.6 24.1 1.6 1 0 0 1 1 1 0 Spore coat protein CotO Activator_LAG-3 PF11498.8 CDJ39561.1 - 7.9 5.3 13.4 10 4.9 13.4 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 ISN1 PF06437.11 CDJ39563.1 - 2.9e-43 148.3 0.0 3.9e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Menin PF05053.13 CDJ39563.1 - 1.6 7.0 8.2 2.6 6.3 8.2 1.2 1 0 0 1 1 1 0 Menin SR-25 PF10500.9 CDJ39564.1 - 0.0039 16.8 15.9 0.0049 16.5 15.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein ALMT PF11744.8 CDJ39564.1 - 2.5 6.8 4.7 3.4 6.4 4.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 CDJ39564.1 - 3.9 5.5 9.0 4.2 5.4 9.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Methyltransf_16 PF10294.9 CDJ39565.1 - 0.22 11.2 0.2 0.33 10.7 0.2 1.2 1 0 0 1 1 1 0 Lysine methyltransferase DUF480 PF04337.12 CDJ39566.1 - 0.0039 17.3 0.5 0.014 15.5 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function, DUF480 Plus-3 PF03126.18 CDJ39566.1 - 0.019 15.5 0.0 0.095 13.2 0.0 1.9 2 0 0 2 2 2 0 Plus-3 domain Med4 PF10018.9 CDJ39566.1 - 0.04 13.6 7.1 0.063 13.0 7.1 1.4 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Fzo_mitofusin PF04799.13 CDJ39566.1 - 0.041 13.4 6.2 0.24 11.0 0.6 2.1 1 1 1 2 2 2 0 fzo-like conserved region DUF4205 PF13898.6 CDJ39566.1 - 0.05 12.5 0.3 0.067 12.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) FUSC PF04632.12 CDJ39566.1 - 0.13 10.8 1.9 0.14 10.6 1.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CRR7 PF12095.8 CDJ39566.1 - 0.16 12.5 1.9 0.7 10.4 0.2 2.2 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 GlutR_dimer PF00745.20 CDJ39566.1 - 0.54 10.7 7.6 1.1 9.7 0.7 2.1 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF4574 PF15141.6 CDJ39567.1 - 0.0083 16.0 0.1 0.0083 16.0 0.1 2.9 2 1 1 3 3 3 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF2203 PF09969.9 CDJ39567.1 - 8.3 7.2 8.0 0.82 10.4 3.4 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) RRM_1 PF00076.22 CDJ39568.1 - 3e-05 23.7 0.0 4.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sin_N PF04801.13 CDJ39569.1 - 0.00025 20.4 0.8 0.00033 20.0 0.1 1.6 1 1 1 2 2 2 1 Sin-like protein conserved region RF-1 PF00472.20 CDJ39570.1 - 3.6e-12 46.2 6.8 6.7e-12 45.4 6.8 1.3 1 0 0 1 1 1 1 RF-1 domain DUF2175 PF09943.9 CDJ39570.1 - 0.023 15.0 1.3 0.038 14.3 1.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) IPP-2 PF04979.14 CDJ39570.1 - 0.96 10.2 7.0 0.2 12.4 1.5 2.1 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) RskA PF10099.9 CDJ39570.1 - 2.1 8.6 9.5 8.4 6.6 9.5 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF1744 PF08490.12 CDJ39572.1 - 0.0032 16.1 0.0 0.013 14.1 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) Helicase_C PF00271.31 CDJ39573.1 - 6.5e-13 49.0 0.0 2.8e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chaperone_III PF07824.12 CDJ39573.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Type III secretion chaperone domain Draxin PF15550.6 CDJ39575.1 - 0.16 11.8 31.7 0.19 11.5 31.7 1.2 1 0 0 1 1 1 0 Draxin GREB1 PF15782.5 CDJ39575.1 - 0.95 6.5 42.1 1.1 6.3 42.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ39575.1 - 1.5 7.0 50.4 1.9 6.7 50.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF572 PF04502.13 CDJ39575.1 - 2.2 7.8 38.2 3.3 7.3 38.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) YL1 PF05764.13 CDJ39575.1 - 3.4 7.7 50.1 4.3 7.4 50.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Dicty_REP PF05086.12 CDJ39575.1 - 3.9 5.3 24.7 4.6 5.1 24.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC27 PF09507.10 CDJ39575.1 - 7.6 5.8 50.9 9.8 5.4 50.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1772 PF08592.11 CDJ39575.1 - 9.2 6.6 9.1 1.5 9.1 4.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) IMUP PF15761.5 CDJ39576.1 - 0.033 14.9 1.4 0.033 14.9 1.4 3.3 4 0 0 4 4 4 0 Immortalisation up-regulated protein DDT PF02791.17 CDJ39576.1 - 0.055 13.8 2.7 2.9 8.3 2.7 2.8 1 1 0 1 1 1 0 DDT domain Ribosomal_S19 PF00203.21 CDJ39576.1 - 5.2 7.0 5.6 0.61 10.0 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein S19 T_Ag_DNA_bind PF02217.16 CDJ39577.1 - 0.017 15.7 0.6 0.048 14.3 0.6 1.7 1 0 0 1 1 1 0 Origin of replication binding protein DUF1269 PF06897.12 CDJ39577.1 - 0.1 12.9 2.8 5 7.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) XK-related PF09815.9 CDJ39578.1 - 0.12 11.4 9.4 0.13 11.3 9.4 1.1 1 0 0 1 1 1 0 XK-related protein V_ATPase_I PF01496.19 CDJ39578.1 - 2.8 5.7 19.3 3.1 5.6 19.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FYDLN_acid PF09538.10 CDJ39578.1 - 5.2 7.8 13.6 0.67 10.7 8.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) Presenilin PF01080.17 CDJ39578.1 - 9.6 4.8 22.6 11 4.7 22.6 1.0 1 0 0 1 1 1 0 Presenilin Sporozoite_P67 PF05642.11 CDJ39580.1 - 0.19 9.7 11.5 0.2 9.7 11.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PH PF00169.29 CDJ39581.1 - 0.00021 21.7 0.0 0.023 15.2 0.0 2.9 3 0 0 3 3 3 1 PH domain IKBKB_SDD PF18397.1 CDJ39581.1 - 0.18 11.0 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain PH_17 PF18012.1 CDJ39581.1 - 3.3 7.5 5.0 0.44 10.3 0.4 2.0 2 0 0 2 2 2 0 PH domain NPR3 PF03666.13 CDJ39582.1 - 2.3e-05 23.4 9.5 3e-05 23.0 9.5 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CDJ39582.1 - 0.00015 20.6 15.4 0.00017 20.5 15.4 1.1 1 0 0 1 1 1 1 Presenilin DUF2828 PF11443.8 CDJ39582.1 - 0.003 15.7 19.1 0.0041 15.3 19.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF913 PF06025.12 CDJ39582.1 - 0.005 15.9 10.3 0.0067 15.4 10.3 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DUF572 PF04502.13 CDJ39582.1 - 0.0058 16.3 12.4 0.007 16.0 12.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) CAF1 PF04857.20 CDJ39582.1 - 0.006 15.8 4.9 0.0055 15.9 4.9 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Lin-8 PF03353.15 CDJ39582.1 - 0.0062 16.1 15.2 0.007 16.0 15.2 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Sin_N PF04801.13 CDJ39582.1 - 0.0069 15.6 22.1 0.0075 15.5 22.1 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region Velvet PF11754.8 CDJ39582.1 - 0.0097 15.9 10.7 0.012 15.6 10.7 1.2 1 0 0 1 1 1 1 Velvet factor Pex14_N PF04695.13 CDJ39582.1 - 0.012 16.2 23.9 0.02 15.6 23.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.10 CDJ39582.1 - 0.014 14.1 7.9 0.014 14.1 7.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 CDJ39582.1 - 0.027 13.7 4.2 0.033 13.4 4.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter VIT1 PF01988.19 CDJ39582.1 - 0.082 12.8 4.3 0.1 12.5 4.3 1.3 1 0 0 1 1 1 0 VIT family SID-1_RNA_chan PF13965.6 CDJ39582.1 - 0.09 11.2 6.0 0.11 10.9 6.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Membralin PF09746.9 CDJ39582.1 - 0.14 11.1 8.3 0.16 11.0 8.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Otopetrin PF03189.13 CDJ39582.1 - 0.19 10.5 6.8 0.2 10.4 6.8 1.1 1 0 0 1 1 1 0 Otopetrin SpoVR PF04293.13 CDJ39582.1 - 0.24 10.0 17.9 0.34 9.6 17.9 1.1 1 0 0 1 1 1 0 SpoVR like protein Dicty_REP PF05086.12 CDJ39582.1 - 0.3 9.0 7.9 0.31 8.9 7.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Exonuc_VII_L PF02601.15 CDJ39582.1 - 0.41 10.2 21.8 0.46 10.0 21.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM60A PF15396.6 CDJ39582.1 - 0.49 10.4 17.2 0.71 9.8 17.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CCDC53 PF10152.9 CDJ39582.1 - 0.51 10.8 17.3 0.84 10.0 17.3 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Connexin PF00029.19 CDJ39582.1 - 0.63 9.8 16.5 1.1 8.9 16.5 1.4 1 0 0 1 1 1 0 Connexin SpoIIP PF07454.11 CDJ39582.1 - 0.66 9.4 19.4 0.98 8.8 19.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4366 PF14283.6 CDJ39582.1 - 0.7 9.9 8.7 0.74 9.9 6.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Scs3p PF10261.9 CDJ39582.1 - 0.76 9.2 6.5 1.2 8.6 6.5 1.3 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM PAT1 PF09770.9 CDJ39582.1 - 0.79 7.9 35.6 0.97 7.6 35.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ39582.1 - 0.9 9.6 16.4 1.3 9.0 16.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 CDJ39582.1 - 0.94 7.7 20.3 1.2 7.3 20.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CBP_BcsG PF11658.8 CDJ39582.1 - 1.1 7.6 16.9 1.6 7.1 16.9 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG LAP1C PF05609.12 CDJ39582.1 - 1.2 8.1 22.6 1.6 7.7 22.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) HCO3_cotransp PF00955.21 CDJ39582.1 - 1.2 7.8 10.2 1.6 7.5 10.2 1.1 1 0 0 1 1 1 0 HCO3- transporter family BORG_CEP PF14957.6 CDJ39582.1 - 1.5 10.0 12.6 2.3 9.4 12.6 1.3 1 0 0 1 1 1 0 Cdc42 effector Afi1 PF07792.12 CDJ39582.1 - 1.5 9.3 19.1 3.3 8.2 19.1 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Kei1 PF08552.11 CDJ39582.1 - 1.5 8.6 11.4 2.4 8.0 11.4 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 ALMT PF11744.8 CDJ39582.1 - 1.7 7.4 17.0 2.3 7.0 17.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2370 PF10176.9 CDJ39582.1 - 1.8 8.2 8.1 2.6 7.6 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) RR_TM4-6 PF06459.12 CDJ39582.1 - 2 8.2 23.5 3.2 7.5 23.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.9 CDJ39582.1 - 2.3 7.8 38.6 3.5 7.2 38.6 1.2 1 0 0 1 1 1 0 DDRGK domain PA26 PF04636.13 CDJ39582.1 - 2.5 6.9 19.5 3.1 6.6 19.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PIP5K PF01504.18 CDJ39582.1 - 2.8 7.1 15.9 4.2 6.5 15.9 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF4050 PF13259.6 CDJ39582.1 - 2.9 8.2 18.4 4.4 7.6 18.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Peptidase_S64 PF08192.11 CDJ39582.1 - 3.2 6.1 17.8 4.4 5.7 17.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF4228 PF14009.6 CDJ39582.1 - 4.4 7.7 14.8 7.9 6.8 14.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) SLC12 PF03522.15 CDJ39582.1 - 5.2 6.0 23.7 7.3 5.5 23.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Tmem26 PF09772.9 CDJ39582.1 - 5.9 6.2 9.1 10 5.3 9.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 26 Sec62 PF03839.16 CDJ39582.1 - 6 6.3 22.2 8.8 5.8 22.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 CSG2 PF16965.5 CDJ39582.1 - 7.2 5.4 12.2 10 5.0 12.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator MDM10 PF12519.8 CDJ39582.1 - 7.7 5.2 18.4 9.8 4.9 18.4 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SPX PF03105.19 CDJ39583.1 - 9.3 6.1 11.2 11 5.8 11.2 1.1 1 0 0 1 1 1 0 SPX domain Cep57_MT_bd PF06657.13 CDJ39584.1 - 0.026 15.0 0.2 0.026 15.0 0.2 6.4 5 1 1 7 7 7 0 Centrosome microtubule-binding domain of Cep57 PBP_N PF17093.5 CDJ39584.1 - 1 9.6 8.4 0.77 10.0 0.2 2.6 1 1 1 2 2 2 0 Penicillin-binding protein N-terminus Apt1 PF10351.9 CDJ39585.1 - 0.011 14.6 4.0 0.012 14.5 4.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ39585.1 - 0.026 14.4 4.7 0.034 14.1 4.7 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 CDJ39585.1 - 0.044 12.4 11.1 0.064 11.8 11.1 1.2 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 CDJ39585.1 - 0.07 11.5 0.1 0.07 11.5 0.1 1.6 2 0 0 2 2 2 0 Menin ANAPC1 PF12859.7 CDJ39585.1 - 0.43 11.1 6.2 0.76 10.3 6.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 DUF4614 PF15391.6 CDJ39585.1 - 0.72 9.8 13.5 1.2 9.1 13.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Pacs-1 PF10254.9 CDJ39585.1 - 1.7 7.5 7.3 2.4 7.0 7.3 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Med3 PF11593.8 CDJ39586.1 - 0.001 18.4 3.5 0.0012 18.1 3.5 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DUF2956 PF11169.8 CDJ39586.1 - 0.29 11.3 7.6 0.43 10.8 7.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2956) TFIIA PF03153.13 CDJ39586.1 - 5.8 6.8 10.2 6.9 6.6 10.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt4 PF06093.13 CDJ39587.1 - 2.4e-21 75.6 0.0 2.7e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Ctr PF04145.15 CDJ39588.1 - 0.00079 20.1 4.9 0.0025 18.4 4.8 1.9 1 1 0 1 1 1 1 Ctr copper transporter family Phage_holin_3_6 PF07332.11 CDJ39588.1 - 0.00084 19.4 0.9 0.00084 19.4 0.9 5.4 3 2 3 6 6 2 1 Putative Actinobacterial Holin-X, holin superfamily III CLN3 PF02487.17 CDJ39588.1 - 0.0015 17.7 0.2 0.0028 16.8 0.2 1.4 1 0 0 1 1 1 1 CLN3 protein Vac7 PF12751.7 CDJ39588.1 - 0.0027 17.2 1.0 0.0043 16.6 1.0 1.3 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 DUF4131 PF13567.6 CDJ39588.1 - 0.0051 16.5 3.4 0.0051 16.5 3.4 4.4 3 2 1 4 4 3 1 Domain of unknown function (DUF4131) SPX PF03105.19 CDJ39588.1 - 0.039 13.9 3.6 0.053 13.4 3.6 1.1 1 0 0 1 1 1 0 SPX domain Wzy_C PF04932.15 CDJ39588.1 - 0.045 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 O-Antigen ligase Herpes_glycop PF01528.16 CDJ39588.1 - 0.077 11.8 0.1 0.14 11.0 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein M PrmA PF06325.13 CDJ39588.1 - 0.12 11.8 1.7 0.18 11.2 1.7 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Presenilin PF01080.17 CDJ39588.1 - 0.13 11.0 1.7 0.22 10.2 1.7 1.3 1 0 0 1 1 1 0 Presenilin Miga PF10265.9 CDJ39588.1 - 0.15 11.0 4.9 0.21 10.6 4.9 1.1 1 0 0 1 1 1 0 Mitoguardin V_ATPase_I PF01496.19 CDJ39588.1 - 0.16 9.9 1.7 0.21 9.5 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GREB1 PF15782.5 CDJ39588.1 - 0.17 9.0 8.0 0.21 8.7 8.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 CDJ39588.1 - 0.28 11.1 21.3 0.52 10.2 21.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF775 PF05603.12 CDJ39588.1 - 0.44 10.1 6.5 0.81 9.2 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF4330 PF14221.6 CDJ39588.1 - 0.46 10.7 1.3 0.99 9.6 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) DUF2052 PF09747.9 CDJ39588.1 - 0.51 10.4 6.0 0.74 9.9 6.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CytochromB561_N PF09786.9 CDJ39588.1 - 1.8 7.5 9.9 5 6.0 9.9 1.6 1 1 0 1 1 1 0 Cytochrome B561, N terminal MAT1 PF06391.13 CDJ39588.1 - 2.8 7.7 9.7 4.1 7.2 9.7 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Lin-8 PF03353.15 CDJ39588.1 - 3.5 7.1 14.0 4.8 6.6 14.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SARAF PF06682.12 CDJ39588.1 - 6.2 6.4 11.9 3.4 7.2 6.7 2.2 1 1 2 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Pkinase PF00069.25 CDJ39589.1 - 8.8e-24 84.3 0.1 1.1e-23 84.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ39589.1 - 1.1e-13 51.1 0.1 1.3e-13 50.8 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RPE65 PF03055.15 CDJ39589.1 - 0.062 12.5 0.0 0.062 12.5 0.0 1.0 1 0 0 1 1 1 0 Retinal pigment epithelial membrane protein His_binding PF02098.16 CDJ39589.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Tick histamine binding protein SufE PF02657.15 CDJ39590.1 - 0.086 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Fe-S metabolism associated domain DUF5343 PF17278.2 CDJ39591.1 - 0.06 13.4 0.2 0.095 12.8 0.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5343) Presenilin PF01080.17 CDJ39592.1 - 0.11 11.3 0.8 0.087 11.6 0.8 1.2 1 0 0 1 1 1 0 Presenilin TMEM214 PF10151.9 CDJ39592.1 - 2.8 6.3 4.4 3.3 6.0 4.4 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator RrnaAD PF00398.20 CDJ39594.1 - 1e-52 178.9 0.0 1.3e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CDJ39594.1 - 0.00047 20.8 0.3 0.0011 19.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ39594.1 - 0.0019 18.0 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CDJ39594.1 - 0.0081 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Robl_LC7 PF03259.17 CDJ39594.1 - 0.12 12.2 0.3 0.12 12.2 0.3 2.2 2 0 0 2 2 2 0 Roadblock/LC7 domain Methyltransf_12 PF08242.12 CDJ39594.1 - 0.18 12.6 0.1 0.54 11.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain SR-25 PF10500.9 CDJ39594.1 - 1.3 8.5 10.7 2.4 7.7 10.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SURF6 PF04935.12 CDJ39596.1 - 0.76 9.5 11.2 0.056 13.2 5.3 1.8 2 0 0 2 2 2 0 Surfeit locus protein 6 TFIIA PF03153.13 CDJ39596.1 - 3.5 7.5 23.4 5.2 6.9 23.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLX9 PF15341.6 CDJ39596.1 - 8.2 6.8 14.1 29 5.0 14.2 1.8 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 SUIM_assoc PF16619.5 CDJ39598.1 - 0.99 9.5 29.7 1.1 9.4 9.8 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SAGA-Tad1 PF12767.7 CDJ39598.1 - 2.1 8.0 15.6 0.13 11.9 9.9 1.8 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit VPS9 PF02204.18 CDJ39600.1 - 0.0013 18.9 0.7 0.0041 17.3 0.4 2.0 2 1 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Rad50_zn_hook PF04423.14 CDJ39600.1 - 0.0032 17.3 1.5 0.0098 15.7 0.1 2.5 2 0 0 2 2 2 1 Rad50 zinc hook motif DivIC PF04977.15 CDJ39600.1 - 0.81 9.5 0.0 0.81 9.5 0.0 5.9 2 2 4 6 6 6 0 Septum formation initiator RskA PF10099.9 CDJ39600.1 - 3.2 8.0 37.0 16 5.8 4.5 3.1 1 1 2 3 3 3 0 Anti-sigma-K factor rskA GIDA_assoc PF13932.6 CDJ39602.1 - 7.5e-10 39.3 0.0 7.5e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 GidA associated domain WTX PF09422.10 CDJ39602.1 - 4 6.4 12.8 6.7 5.7 12.8 1.3 1 0 0 1 1 1 0 WTX protein Asp-B-Hydro_N PF05279.11 CDJ39602.1 - 5.2 7.1 10.9 7.5 6.5 10.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TFIIA PF03153.13 CDJ39602.1 - 7.4 6.5 32.9 10 6.0 32.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nuf2 PF03800.14 CDJ39604.1 - 5.3e-08 33.1 0.0 3e-07 30.6 0.0 2.2 1 1 1 2 2 2 1 Nuf2 family LMBR1 PF04791.16 CDJ39604.1 - 0.0052 15.8 10.6 0.0087 15.0 10.6 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein Fibin PF15819.5 CDJ39604.1 - 0.17 11.6 10.9 0.26 11.0 10.9 1.3 1 0 0 1 1 1 0 Fin bud initiation factor homologue OmpH PF03938.14 CDJ39605.1 - 0.013 15.9 2.5 0.013 15.9 2.5 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Spc29 PF17082.5 CDJ39605.1 - 0.11 12.3 2.9 0.68 9.7 0.3 2.1 2 0 0 2 2 2 0 Spindle Pole Component 29 MCU PF04678.13 CDJ39605.1 - 0.8 9.8 3.9 0.68 10.0 1.1 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF4770 PF15994.5 CDJ39605.1 - 7.3 6.8 10.4 2.3 8.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Peptidase_S28 PF05577.12 CDJ39606.1 - 0.04 12.7 0.2 6.1 5.5 0.0 2.8 3 0 0 3 3 3 0 Serine carboxypeptidase S28 SR-25 PF10500.9 CDJ39606.1 - 2.1 7.9 8.6 0.078 12.6 2.7 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ39607.1 - 0.046 13.7 21.7 0.063 13.3 21.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit THOC2_N PF16134.5 CDJ39607.1 - 1.3 7.5 6.3 2.1 6.9 6.3 1.3 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Presenilin PF01080.17 CDJ39607.1 - 3.7 6.2 4.6 4.3 6.0 4.6 1.3 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 CDJ39609.1 - 0.0033 16.9 30.2 0.0052 16.3 30.2 1.3 1 0 0 1 1 1 1 SDA1 RskA PF10099.9 CDJ39609.1 - 0.013 15.8 14.9 0.013 15.8 14.9 3.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA PA26 PF04636.13 CDJ39609.1 - 0.038 12.9 24.6 0.0087 15.0 15.9 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Zip PF02535.22 CDJ39609.1 - 0.56 9.4 18.7 0.023 14.0 11.1 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter AP2 PF00847.20 CDJ39610.1 - 5.4e-06 26.5 2.9 1.2e-05 25.4 2.9 1.5 1 0 0 1 1 1 1 AP2 domain Med15 PF09606.10 CDJ39610.1 - 3.9 6.0 40.6 0.4 9.3 24.9 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DTW PF03942.15 CDJ39611.1 - 2.8e-16 59.8 1.2 6.5e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 DTW domain RskA PF10099.9 CDJ39611.1 - 0.015 15.6 12.5 0.015 15.6 12.5 5.5 1 1 2 4 4 4 0 Anti-sigma-K factor rskA SID-1_RNA_chan PF13965.6 CDJ39611.1 - 0.3 9.5 0.6 0.44 8.9 0.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Connexin PF00029.19 CDJ39611.1 - 0.61 9.8 9.6 0.08 12.7 2.3 2.7 3 0 0 3 3 3 0 Connexin EPL1 PF10513.9 CDJ39611.1 - 1.2 9.5 19.9 3.5 8.0 10.2 3.2 3 0 0 3 3 3 0 Enhancer of polycomb-like Neur_chan_memb PF02932.16 CDJ39611.1 - 1.6 8.7 16.3 0.18 11.8 4.0 3.0 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Myc_N PF01056.18 CDJ39611.1 - 1.9 8.3 12.6 0.35 10.7 8.0 2.1 2 0 0 2 2 2 0 Myc amino-terminal region MID_MedPIWI PF18296.1 CDJ39611.1 - 5.2 6.8 15.6 0.22 11.3 5.2 2.9 3 0 0 3 3 3 0 MID domain of medPIWI Endostatin PF06482.11 CDJ39611.1 - 5.7 6.3 19.6 0.01 15.4 6.0 2.5 3 0 0 3 3 3 0 Collagenase NC10 and Endostatin PLU-1 PF08429.11 CDJ39612.1 - 0.17 11.0 0.4 0.55 9.3 0.4 1.7 1 1 0 1 1 1 0 PLU-1-like protein CHASE3 PF05227.13 CDJ39612.1 - 0.24 11.3 3.1 1.2 9.1 0.0 2.6 1 1 1 2 2 2 0 CHASE3 domain ADP_PFK_GK PF04587.15 CDJ39614.1 - 0.0076 14.9 0.3 0.011 14.3 0.3 1.2 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region TFIIA PF03153.13 CDJ39614.1 - 0.015 15.3 17.1 0.018 15.1 17.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ39614.1 - 0.082 12.5 3.5 0.1 12.1 3.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Band_3_cyto PF07565.13 CDJ39614.1 - 0.33 10.7 2.9 0.54 10.0 2.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Suf PF05843.14 CDJ39614.1 - 0.38 10.7 4.6 0.63 10.0 4.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ39614.1 - 0.4 9.4 4.9 0.6 8.8 4.9 1.3 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ39614.1 - 0.86 9.4 3.9 1.2 8.9 3.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ACPS PF01648.20 CDJ39616.1 - 9.3e-15 54.8 0.0 2.3e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Nup54 PF13874.6 CDJ39616.1 - 0.098 12.8 0.3 0.22 11.6 0.3 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Pox_MCEL PF03291.16 CDJ39617.1 - 7.8e-10 38.4 0.0 0.00095 18.4 0.0 2.5 2 1 0 2 2 2 2 mRNA capping enzyme Ecl1 PF12855.7 CDJ39617.1 - 0.035 15.3 27.5 0.4 11.8 10.9 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins GHMP_kinases_C PF08544.13 CDJ39617.1 - 0.1 12.9 1.3 0.9 9.9 0.0 3.0 2 0 0 2 2 2 0 GHMP kinases C terminal DUF1645 PF07816.11 CDJ39617.1 - 0.39 11.3 21.7 3.6 8.1 7.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) SR-25 PF10500.9 CDJ39617.1 - 0.62 9.6 34.5 2.5 7.6 15.0 2.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 CDJ39617.1 - 0.68 8.4 18.4 0.099 11.2 1.8 2.3 2 0 0 2 2 2 0 Macoilin family eIF3g PF12353.8 CDJ39618.1 - 1.6 9.1 16.9 0.28 11.6 7.4 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Lin-8 PF03353.15 CDJ39618.1 - 7.1 6.1 25.7 11 5.5 25.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2722 PF10846.8 CDJ39619.1 - 0.0022 17.1 4.1 0.0022 17.1 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Androgen_recep PF02166.16 CDJ39619.1 - 0.0028 16.6 15.3 0.0031 16.4 15.3 1.1 1 0 0 1 1 1 1 Androgen receptor BSMAP PF12280.8 CDJ39619.1 - 0.02 15.1 0.6 0.022 15.0 0.6 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein Pex14_N PF04695.13 CDJ39619.1 - 0.044 14.4 7.3 0.046 14.4 7.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tim54 PF11711.8 CDJ39619.1 - 0.063 12.0 0.8 0.062 12.1 0.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.13 CDJ39619.1 - 0.2 11.6 13.6 0.21 11.5 13.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ39619.1 - 0.23 11.0 12.3 0.24 11.0 12.3 1.1 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 CDJ39619.1 - 0.25 10.5 17.5 0.3 10.2 17.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4366 PF14283.6 CDJ39619.1 - 1.3 9.0 4.5 3.3 7.7 4.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 CDJ39619.1 - 3.1 6.5 4.2 3 6.5 4.2 1.1 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 CDJ39619.1 - 3.7 7.7 6.9 4.4 7.5 6.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3464 PF11947.8 CDJ39619.1 - 7.7 6.3 6.6 9.3 6.0 6.6 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Nup96 PF12110.8 CDJ39621.1 - 3.5e-12 46.1 4.3 3.5e-12 46.1 4.3 2.1 2 0 0 2 2 2 1 Nuclear protein 96 SUIM_assoc PF16619.5 CDJ39621.1 - 0.048 13.7 0.7 0.048 13.7 0.7 5.6 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 DUF3458 PF11940.8 CDJ39621.1 - 0.54 10.7 4.5 0.78 10.2 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3458) Ig-like fold Prp19 PF08606.11 CDJ39622.1 - 7.9e-10 38.6 0.1 1.3e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like TGT PF01702.18 CDJ39623.1 - 5.5e-10 38.9 0.1 4.2e-09 36.0 0.1 1.9 2 0 0 2 2 2 1 Queuine tRNA-ribosyltransferase K_channel_TID PF07941.11 CDJ39623.1 - 0.00075 19.9 5.2 0.00075 19.9 5.2 5.7 4 1 1 5 5 5 2 Potassium channel Kv1.4 tandem inactivation domain PmbA_TldD PF01523.16 CDJ39623.1 - 0.82 9.5 6.5 2.9 7.7 0.1 2.3 2 0 0 2 2 2 0 Putative modulator of DNA gyrase TPR_MLP1_2 PF07926.12 CDJ39624.1 - 0.0027 17.7 19.1 0.0027 17.7 19.1 4.7 2 2 1 4 4 4 1 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 CDJ39624.1 - 0.039 14.0 1.1 0.039 14.0 1.1 3.8 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 CDJ39624.1 - 0.094 12.0 56.1 0.66 9.3 18.8 4.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 CDJ39624.1 - 0.16 12.2 35.3 0.34 11.1 6.4 3.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family SpoVAD PF07451.11 CDJ39624.1 - 0.2 10.3 1.5 0.44 9.2 1.5 1.5 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) CENP-F_leu_zip PF10473.9 CDJ39624.1 - 0.53 10.3 59.0 4.5 7.3 11.5 5.5 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_F PF12259.8 CDJ39624.1 - 0.6 8.6 14.9 0.026 13.0 5.2 2.2 2 0 0 2 2 2 0 Baculovirus F protein ETRAMP PF09716.10 CDJ39624.1 - 1 9.5 0.0 1 9.5 0.0 2.5 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF2203 PF09969.9 CDJ39624.1 - 2 9.2 38.1 0.52 11.0 5.0 4.2 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) COG5 PF10392.9 CDJ39624.1 - 5.7 7.1 21.0 0.57 10.4 8.2 3.3 2 2 0 2 2 2 0 Golgi transport complex subunit 5 Spc7 PF08317.11 CDJ39624.1 - 8.6 5.1 55.5 0.14 11.0 17.8 3.3 1 1 3 4 4 4 0 Spc7 kinetochore protein Ribosomal_L36e PF01158.18 CDJ39626.1 - 1.6e-38 130.8 4.6 1.8e-38 130.6 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Bystin PF05291.11 CDJ39627.1 - 1.8e-111 372.1 3.2 2.5e-111 371.6 3.2 1.1 1 0 0 1 1 1 1 Bystin HemY_N PF07219.13 CDJ39629.1 - 0.046 13.9 1.0 0.046 13.9 1.0 2.0 2 0 0 2 2 2 0 HemY protein N-terminus DUF962 PF06127.11 CDJ39629.1 - 0.51 10.4 2.1 1.3 9.2 2.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Peptidase_C1 PF00112.23 CDJ39630.1 - 3.8e-51 174.3 1.0 5.2e-51 173.8 1.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 CDJ39630.1 - 0.0062 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C1 propeptide Glycolytic PF00274.19 CDJ39631.1 - 0.19 10.4 0.1 0.28 9.9 0.1 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I MCM PF00493.23 CDJ39632.1 - 4.3e-93 310.5 0.1 7.8e-93 309.7 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDJ39632.1 - 6.1e-27 94.0 0.2 1.7e-26 92.5 0.2 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDJ39632.1 - 2.1e-26 92.2 2.9 3.9e-26 91.3 2.9 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDJ39632.1 - 9.5e-07 28.4 0.1 5.1e-06 26.0 0.1 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_lid_7 PF17867.1 CDJ39632.1 - 0.0026 17.9 0.8 0.0065 16.7 0.8 1.6 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_3 PF07726.11 CDJ39632.1 - 0.0038 17.1 0.0 0.01 15.7 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ39632.1 - 0.037 14.0 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 CDJ39632.1 - 0.11 13.2 1.6 0.4 11.4 1.6 2.0 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal BAG PF02179.16 CDJ39632.1 - 0.99 9.9 6.1 0.25 11.8 0.3 2.8 3 0 0 3 3 3 0 BAG domain U1snRNP70_N PF12220.8 CDJ39634.1 - 1.3 9.7 18.2 3.5 8.3 0.3 3.2 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ACDC PF14733.6 CDJ39636.1 - 1.4e-13 51.0 0.2 4.4e-13 49.4 0.2 1.9 1 0 0 1 1 1 1 AP2-coincident C-terminal GATase_2 PF00310.21 CDJ39637.1 - 0.53 8.9 8.5 0.95 8.1 8.5 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II V_ATPase_I PF01496.19 CDJ39637.1 - 2.2 6.1 22.9 2.2 6.1 3.3 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4834 PF16118.5 CDJ39638.1 - 0.027 15.4 2.4 0.027 15.4 2.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) RS4NT PF08071.12 CDJ39638.1 - 0.043 13.9 0.2 0.075 13.2 0.2 1.3 1 0 0 1 1 1 0 RS4NT (NUC023) domain CCSAP PF15748.5 CDJ39638.1 - 0.051 13.7 18.8 0.068 13.3 18.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF5320 PF17253.2 CDJ39638.1 - 0.068 14.2 2.2 0.068 14.2 2.2 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5320) Exonuc_VII_L PF02601.15 CDJ39638.1 - 0.075 12.6 26.4 0.1 12.2 26.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SID-1_RNA_chan PF13965.6 CDJ39638.1 - 0.13 10.7 7.1 0.046 12.1 4.8 1.3 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.7 CDJ39638.1 - 4.1 5.4 19.9 5 5.1 19.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Caldesmon PF02029.15 CDJ39638.1 - 7.1 5.3 37.8 9.3 4.9 37.8 1.1 1 0 0 1 1 1 0 Caldesmon Complex1_LYR_2 PF13233.6 CDJ39639.1 - 0.0045 17.7 6.3 0.0045 17.7 6.3 2.6 2 1 0 2 2 2 1 Complex1_LYR-like DUF4179 PF13786.6 CDJ39639.1 - 0.0085 16.5 6.4 0.54 10.8 1.1 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4179) SR-25 PF10500.9 CDJ39639.1 - 0.063 12.9 15.4 0.061 12.9 7.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CD20 PF04103.15 CDJ39639.1 - 0.081 13.0 1.4 0.68 10.0 0.1 2.1 2 0 0 2 2 2 0 CD20-like family Spt20 PF12090.8 CDJ39639.1 - 0.086 12.4 33.3 0.31 10.6 19.6 2.4 2 0 0 2 2 2 0 Spt20 family BSMAP PF12280.8 CDJ39639.1 - 0.77 9.9 13.3 1.1 9.4 1.3 2.3 2 0 0 2 2 2 0 Brain specific membrane anchored protein CRF1 PF10380.9 CDJ39639.1 - 1.4 9.3 4.9 1.1 9.7 0.8 2.4 2 0 0 2 2 2 0 Transcription factor CRF1 SprA-related PF12118.8 CDJ39639.1 - 1.5 7.9 44.3 1 8.4 25.3 2.2 2 0 0 2 2 2 0 SprA-related family DUF719 PF05334.13 CDJ39639.1 - 4.9 7.3 19.0 9.3 6.4 10.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) TRM13 PF05206.14 CDJ39639.1 - 6 6.3 12.2 1.3 8.4 3.0 2.6 2 1 0 2 2 2 0 Methyltransferase TRM13 Ureide_permease PF07168.11 CDJ39639.1 - 8.6 5.0 14.9 0.86 8.3 4.2 2.5 1 1 2 3 3 3 0 Ureide permease RNB PF00773.19 CDJ39640.1 - 1.4e-27 96.9 0.1 1.7e-27 96.6 0.1 1.1 1 0 0 1 1 1 1 RNB domain SUIM_assoc PF16619.5 CDJ39640.1 - 0.37 10.9 10.6 0.058 13.5 6.0 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 OB_Dis3 PF17849.1 CDJ39641.1 - 6.8e-13 48.4 0.0 1.9e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 CDJ39641.1 - 9.3e-05 22.5 4.4 0.012 15.7 0.0 3.4 3 0 0 3 3 3 2 Cold shock domain Rrp44_CSD1 PF17216.3 CDJ39641.1 - 0.00011 22.0 0.7 0.00022 20.9 0.0 1.9 2 0 0 2 2 2 1 Rrp44-like cold shock domain OB_RNB PF08206.11 CDJ39641.1 - 0.024 14.3 0.7 0.087 12.5 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF3446 PF11928.8 CDJ39641.1 - 0.063 13.6 28.2 0.19 12.0 8.0 2.8 3 0 0 3 3 3 0 Early growth response N-terminal domain Chorion_2 PF03964.15 CDJ39641.1 - 0.075 13.9 11.8 0.3 11.9 1.2 2.4 2 0 0 2 2 2 0 Chorion family 2 COPI_assoc PF08507.10 CDJ39642.1 - 0.015 15.4 5.9 0.029 14.4 5.9 1.5 1 1 0 1 1 1 0 COPI associated protein RskA PF10099.9 CDJ39642.1 - 0.055 13.8 7.0 3.2 8.0 6.0 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA YlqD PF11068.8 CDJ39642.1 - 0.38 11.1 7.7 0.064 13.6 1.9 2.0 2 0 0 2 2 2 0 YlqD protein Promethin PF16015.5 CDJ39642.1 - 1.1 9.2 8.7 0.072 13.0 1.5 2.1 1 1 1 2 2 2 0 Promethin Enkurin PF13864.6 CDJ39643.1 - 8e-22 77.5 0.5 8e-22 77.5 0.5 2.1 2 0 0 2 2 2 1 Calmodulin-binding DUF2722 PF10846.8 CDJ39643.1 - 0.54 9.1 14.6 0.84 8.5 14.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SID-1_RNA_chan PF13965.6 CDJ39644.1 - 0.13 10.7 6.9 0.14 10.5 6.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hamartin PF04388.12 CDJ39644.1 - 0.43 9.2 17.3 0.5 9.0 17.3 1.0 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 CDJ39644.1 - 0.58 10.1 31.4 0.67 9.9 31.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ39644.1 - 0.63 9.9 22.1 0.76 9.6 22.1 1.0 1 0 0 1 1 1 0 SPX domain DUF4551 PF15087.6 CDJ39644.1 - 0.79 8.5 21.2 0.94 8.2 21.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) BAF1_ABF1 PF04684.13 CDJ39644.1 - 0.92 8.5 19.5 1 8.3 19.5 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 CDJ39644.1 - 1.1 7.9 21.2 1.2 7.9 21.2 1.1 1 0 0 1 1 1 0 Presenilin Retinal PF15449.6 CDJ39644.1 - 1.2 6.8 26.8 1.4 6.6 26.8 1.0 1 0 0 1 1 1 0 Retinal protein Suf PF05843.14 CDJ39644.1 - 2.3 8.1 20.9 3.5 7.5 20.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4690 PF15756.5 CDJ39644.1 - 2.3 8.9 6.7 0.46 11.1 2.9 1.7 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF1387 PF07139.11 CDJ39644.1 - 3.7 7.2 21.1 5 6.8 21.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Herpes_DNAp_acc PF04929.12 CDJ39644.1 - 5.1 6.0 17.0 6.7 5.6 17.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SAPS PF04499.15 CDJ39644.1 - 5.2 5.7 12.1 6.4 5.4 12.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paf1 PF03985.13 CDJ39644.1 - 7.2 5.5 18.0 9.6 5.1 18.0 1.2 1 0 0 1 1 1 0 Paf1 CDK5_activator PF03261.15 CDJ39644.1 - 8.8 5.8 17.2 10 5.5 17.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Complex1_LYR PF05347.15 CDJ39645.1 - 0.035 14.2 0.4 0.66 10.1 0.1 2.3 2 0 0 2 2 2 0 Complex 1 protein (LYR family) tRNA-synt_1b PF00579.25 CDJ39646.1 - 2.1e-59 201.2 0.0 2.8e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PDEase_I PF00233.19 CDJ39647.1 - 2.4e-77 259.9 1.6 2.4e-77 259.9 1.6 1.5 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Dpy19 PF10034.9 CDJ39648.1 - 8e-76 255.6 0.8 1.1e-29 103.2 0.0 4.0 1 1 2 4 4 4 4 Q-cell neuroblast polarisation TPR_1 PF00515.28 CDJ39648.1 - 0.22 11.4 1.1 0.35 10.8 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ39648.1 - 9.7 6.6 9.7 0.76 10.0 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyoxalase PF00903.25 CDJ39649.1 - 3.2e-34 117.9 0.0 6.8e-16 58.6 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CDJ39649.1 - 5.7e-14 52.3 0.0 5.5e-06 26.6 0.0 3.0 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 CDJ39649.1 - 6.6e-08 33.3 0.0 0.0005 20.8 0.0 2.9 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 CDJ39649.1 - 1.6e-05 25.1 0.0 0.0056 16.8 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 CDJ39649.1 - 7.2e-05 22.7 0.0 0.69 9.9 0.0 4.0 4 0 0 4 4 4 1 Glyoxalase-like domain CppA_N PF14506.6 CDJ39649.1 - 0.0049 16.9 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 CppA N-terminal DUF3081 PF11280.8 CDJ39649.1 - 0.036 13.9 0.0 0.87 9.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3081) RAP PF08373.10 CDJ39650.1 - 0.066 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 RAP domain IHABP4_N PF16174.5 CDJ39650.1 - 4.3 7.9 8.5 28 5.3 4.6 2.5 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal PTPLA PF04387.14 CDJ39651.1 - 1.5e-52 177.6 8.8 2.4e-52 177.0 8.8 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DivIC PF04977.15 CDJ39652.1 - 0.058 13.2 0.9 0.13 12.1 0.9 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 CDJ39652.1 - 3.4 7.8 8.2 0.19 11.8 0.9 2.5 3 0 0 3 3 3 0 bZIP transcription factor WD40 PF00400.32 CDJ39654.1 - 4.1e-36 122.4 25.8 8.6e-09 35.9 0.1 8.8 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ39654.1 - 2.5e-09 37.3 0.0 0.006 16.8 0.0 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ39654.1 - 3.2e-06 26.1 2.8 0.53 8.9 0.0 4.0 3 1 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CDJ39654.1 - 0.0018 17.1 0.2 0.12 11.1 0.0 2.6 2 1 1 3 3 3 1 Nup133 N terminal like Ge1_WD40 PF16529.5 CDJ39654.1 - 0.016 14.2 2.3 1.8 7.5 0.3 3.4 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Lipase_3 PF01764.25 CDJ39655.1 - 1.4e-16 60.6 0.0 2.7e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDJ39655.1 - 0.034 14.8 0.9 0.21 12.2 0.0 2.5 1 1 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 CDJ39655.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Hydrolase_4 PF12146.8 CDJ39655.1 - 0.15 11.3 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Sec7_N PF12783.7 CDJ39660.1 - 4.5e-11 42.9 8.1 1e-10 41.8 8.1 1.5 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4050 PF13259.6 CDJ39660.1 - 1.3 9.3 7.1 1.6 9.0 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Ctr PF04145.15 CDJ39660.1 - 3.6 8.2 13.3 6.7 7.3 3.5 3.3 2 1 0 2 2 2 0 Ctr copper transporter family Chorion_S16 PF05836.12 CDJ39661.1 - 7.5 6.8 16.5 0.33 11.2 0.7 2.1 2 0 0 2 2 2 0 Chorion protein S16 Spt20 PF12090.8 CDJ39662.1 - 0.03 13.9 31.0 0.046 13.3 3.1 3.2 3 0 0 3 3 3 0 Spt20 family Mito_carr PF00153.27 CDJ39663.1 - 0.00013 21.8 1.7 0.00028 20.7 0.5 1.9 1 1 1 2 2 2 2 Mitochondrial carrier protein RIFIN PF02009.16 CDJ39664.1 - 2.8 7.7 17.0 3.4 7.5 17.0 1.0 1 0 0 1 1 1 0 Rifin MCM PF00493.23 CDJ39666.1 - 3e-78 262.0 0.0 4.7e-78 261.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 CDJ39666.1 - 2.1e-07 30.5 0.3 1.6e-05 24.4 0.3 2.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CDJ39666.1 - 0.00042 20.1 0.1 0.0077 15.9 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 CDJ39666.1 - 0.0044 17.0 0.0 0.016 15.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDJ39666.1 - 0.0049 16.7 0.1 0.013 15.3 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M20 PF01546.28 CDJ39666.1 - 0.089 12.5 0.0 0.22 11.2 0.0 1.9 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 AAA_16 PF13191.6 CDJ39666.1 - 0.24 11.7 9.9 1.2 9.5 4.0 3.7 2 1 0 2 2 2 0 AAA ATPase domain Mito_carr PF00153.27 CDJ39667.1 - 2.8e-07 30.4 1.1 3.6e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial carrier protein Dehydrin PF00257.19 CDJ39668.1 - 6.2 7.3 31.8 0.13 12.8 1.7 4.0 2 1 1 3 3 3 0 Dehydrin Ribosomal_60s PF00428.19 CDJ39668.1 - 6.4 7.4 34.9 11 6.7 5.6 4.5 4 0 0 4 4 4 0 60s Acidic ribosomal protein Miga PF10265.9 CDJ39668.1 - 8.5 5.2 11.9 1.1 8.2 0.6 2.2 2 0 0 2 2 2 0 Mitoguardin BAF1_ABF1 PF04684.13 CDJ39669.1 - 2.4 7.1 5.3 3 6.8 5.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor IMCp PF12314.8 CDJ39670.1 - 8.8e-30 102.9 67.2 3.9e-18 65.5 25.6 5.3 1 1 4 5 5 5 5 Inner membrane complex protein CAP_N PF01213.19 CDJ39672.1 - 0.0021 17.6 5.9 0.0029 17.2 5.9 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CDJ39672.1 - 0.026 14.6 4.0 0.045 13.8 4.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TFIIA PF03153.13 CDJ39672.1 - 0.042 13.9 14.3 0.048 13.6 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cytochrom_B558a PF05038.13 CDJ39672.1 - 0.066 12.8 1.1 0.086 12.4 1.1 1.1 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Pex14_N PF04695.13 CDJ39672.1 - 0.14 12.8 12.3 0.23 12.1 12.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SUIM_assoc PF16619.5 CDJ39672.1 - 0.17 12.0 23.6 0.088 12.9 3.0 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF1668 PF07893.13 CDJ39672.1 - 0.32 10.3 5.2 1.7 7.9 5.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1668) NOZZLE PF08744.10 CDJ39672.1 - 0.39 10.2 0.9 0.52 9.7 0.9 1.1 1 0 0 1 1 1 0 Plant transcription factor NOZZLE CCDC53 PF10152.9 CDJ39672.1 - 0.69 10.3 7.9 1.1 9.7 7.9 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2076 PF09849.9 CDJ39672.1 - 2 8.4 18.6 2.8 7.9 18.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SARAF PF06682.12 CDJ39672.1 - 2.1 7.9 10.1 2.8 7.5 10.1 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Helicase_C PF00271.31 CDJ39673.1 - 0.018 15.3 0.0 0.025 14.9 0.0 1.1 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Phage_stabilise PF11134.8 CDJ39673.1 - 0.15 10.9 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Phage stabilisation protein DUF3138 PF11336.8 CDJ39673.1 - 9.8 4.7 14.1 12 4.4 14.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ion_trans_2 PF07885.16 CDJ39674.1 - 3.6e-12 46.1 0.4 9.9e-12 44.7 0.4 1.8 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.18 CDJ39674.1 - 9.5e-05 22.5 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 CDJ39674.1 - 0.018 14.3 6.7 0.027 13.7 6.7 1.2 1 0 0 1 1 1 0 Ion transport protein DUF1345 PF07077.11 CDJ39674.1 - 4.1 7.1 9.3 2.3 7.9 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1345) Kinesin PF00225.23 CDJ39675.1 - 2.1e-12 46.6 0.0 2.4e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ39675.1 - 0.0096 15.9 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding DUF1659 PF07872.11 CDJ39675.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) Patatin PF01734.22 CDJ39678.1 - 2.5e-05 24.6 0.1 3.2e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase Spt20 PF12090.8 CDJ39679.1 - 0.00031 20.4 21.0 0.00031 20.4 21.0 3.6 2 1 1 3 3 3 1 Spt20 family RskA PF10099.9 CDJ39679.1 - 0.01 16.2 18.6 0.01 16.2 18.6 4.8 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Hamartin PF04388.12 CDJ39679.1 - 3.2 6.3 41.3 4.8 5.7 41.3 1.2 1 0 0 1 1 1 0 Hamartin protein eIF-3_zeta PF05091.12 CDJ39679.1 - 7 5.5 41.1 1.3 7.9 12.8 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.25 CDJ39680.1 - 5.5e-13 48.9 0.0 2e-07 30.7 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ39680.1 - 2.4e-05 23.8 0.0 5.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.6 CDJ39680.1 - 0.077 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 CDJ39680.1 - 0.11 12.9 0.0 0.53 10.8 0.0 2.0 2 1 1 3 3 3 0 EF-hand domain pair DUF4698 PF15769.5 CDJ39680.1 - 0.85 8.6 9.8 1.1 8.2 5.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) PI3K_1B_p101 PF10486.9 CDJ39680.1 - 1.6 6.4 17.4 0.031 12.1 10.3 1.6 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Usp PF00582.26 CDJ39683.1 - 0.05 14.1 3.3 1.9 9.0 3.3 2.5 1 1 0 1 1 1 0 Universal stress protein family Spc7_N PF15402.6 CDJ39683.1 - 1.6 6.9 29.0 0.028 12.7 19.9 1.9 1 1 1 2 2 2 0 N-terminus of kinetochore NMS complex subunit Spc7 Nucleo_P87 PF07267.11 CDJ39683.1 - 6.6 5.5 13.5 7.4 5.3 13.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AAA_24 PF13479.6 CDJ39684.1 - 0.0047 16.7 3.9 0.0081 15.9 3.9 1.3 1 0 0 1 1 1 1 AAA domain FAM91_C PF14648.6 CDJ39684.1 - 0.19 10.5 3.3 0.28 10.0 3.3 1.2 1 0 0 1 1 1 0 FAM91 C-terminus SLC12 PF03522.15 CDJ39684.1 - 1 8.3 9.4 1.9 7.4 9.4 1.5 1 0 0 1 1 1 0 Solute carrier family 12 PCI PF01399.27 CDJ39685.1 - 7.7e-06 26.4 2.1 9.7e-06 26.0 0.1 2.2 2 0 0 2 2 2 1 PCI domain Chorion_2 PF03964.15 CDJ39685.1 - 2.1 9.2 6.5 4.8 8.1 6.5 1.5 1 0 0 1 1 1 0 Chorion family 2 Exonuc_VII_L PF02601.15 CDJ39685.1 - 2.3 7.7 9.4 4.2 6.8 9.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dehydratase_SU PF02287.15 CDJ39686.1 - 0.0021 18.1 0.1 0.0024 17.9 0.1 1.1 1 0 0 1 1 1 1 Dehydratase small subunit RRM_1 PF00076.22 CDJ39687.1 - 0.035 13.9 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sporozoite_P67 PF05642.11 CDJ39687.1 - 4 5.4 22.0 10 4.0 22.0 1.8 1 1 0 1 1 1 0 Sporozoite P67 surface antigen CLN3 PF02487.17 CDJ39687.1 - 6.4 5.7 8.2 16 4.4 8.2 1.6 1 0 0 1 1 1 0 CLN3 protein PTH2 PF01981.16 CDJ39688.1 - 1.3e-15 57.7 0.0 1.4e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Dymeclin PF09742.9 CDJ39689.1 - 4 5.7 6.8 6.8 5.0 6.8 1.5 1 1 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein SMC_N PF02463.19 CDJ39691.1 - 1.9e-24 86.4 1.3 4.5e-24 85.1 1.2 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDJ39691.1 - 2.2e-10 40.9 0.0 2.2e-10 40.9 0.0 4.2 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain BPD_transp_2 PF02653.16 CDJ39691.1 - 0.027 13.7 1.6 0.037 13.2 0.7 1.6 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component Lactamase_B_6 PF16661.5 CDJ39692.1 - 0.00011 21.7 0.0 0.00012 21.5 0.0 1.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 CDJ39692.1 - 0.073 12.6 0.1 0.085 12.4 0.1 1.1 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ39692.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.0 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily SR-25 PF10500.9 CDJ39693.1 - 0.0059 16.3 33.2 0.0059 16.3 33.2 4.2 2 1 2 4 4 4 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ39693.1 - 0.0092 16.3 7.7 0.0092 16.3 7.7 4.4 1 1 2 3 3 3 1 Anti-sigma-K factor rskA SPX PF03105.19 CDJ39694.1 - 0.23 11.4 22.5 0.29 11.0 22.5 1.3 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 CDJ39694.1 - 0.37 10.4 50.4 1 8.9 23.1 2.3 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Fusion_gly PF00523.18 CDJ39694.1 - 3.5 5.8 8.7 5.9 5.0 8.7 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 MAP65_ASE1 PF03999.12 CDJ39694.1 - 3.8 6.1 23.1 4.9 5.7 23.1 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF936 PF06075.12 CDJ39694.1 - 4.1 6.2 29.8 5.5 5.8 29.8 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) XRN_M PF17846.1 CDJ39696.1 - 1.2e-13 50.9 0.2 2e-13 50.1 0.1 1.3 1 1 0 1 1 1 1 Xrn1 helical domain TAF4 PF05236.14 CDJ39696.1 - 3.6 7.2 6.0 9.2 5.9 1.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family SDA1 PF05285.12 CDJ39697.1 - 0.035 13.5 3.8 0.046 13.2 3.8 1.2 1 0 0 1 1 1 0 SDA1 Peptidase_S64 PF08192.11 CDJ39697.1 - 1.3 7.4 15.6 1.7 7.1 15.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.13 CDJ39698.1 - 0.26 11.2 30.8 0.039 13.9 15.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ39698.1 - 3.2 8.4 18.6 0.21 12.2 6.2 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ39698.1 - 4.7 7.1 16.2 0.22 11.5 4.5 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF202 PF02656.15 CDJ39699.1 - 0.075 13.5 0.6 0.44 11.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) CAP_N PF01213.19 CDJ39699.1 - 0.23 10.9 5.5 0.25 10.8 5.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 CDJ39699.1 - 0.26 11.3 6.1 0.32 11.0 6.1 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator Med3 PF11593.8 CDJ39699.1 - 3.7 6.6 18.5 4.2 6.4 18.5 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.25 CDJ39700.1 - 5.1e-27 94.9 0.0 3e-26 92.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ39700.1 - 5.8e-10 38.9 1.4 8e-09 35.1 1.4 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2572 PF10833.8 CDJ39700.1 - 0.01 15.6 2.8 0.013 15.2 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Kdo PF06293.14 CDJ39700.1 - 0.013 14.9 0.7 0.023 14.1 0.7 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ39700.1 - 0.029 13.2 1.0 0.14 10.9 1.0 2.0 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CDJ39700.1 - 0.046 13.6 5.2 0.056 13.4 4.8 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF2967 PF11179.8 CDJ39700.1 - 6.5 4.7 6.4 8.4 4.3 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) ABC_tran PF00005.27 CDJ39701.1 - 2.8e-07 31.2 0.0 4.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CDJ39701.1 - 1e-05 25.3 0.0 1.3e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Aquarius_N PF16399.5 CDJ39702.1 - 2e-06 26.2 0.1 2e-06 26.2 0.1 2.2 1 1 1 3 3 3 1 Intron-binding protein aquarius N-terminus TAF4 PF05236.14 CDJ39702.1 - 0.0032 17.3 23.7 0.0032 17.3 23.7 1.4 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family BAF1_ABF1 PF04684.13 CDJ39702.1 - 0.14 11.2 8.0 0.16 11.0 8.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Borrelia_P83 PF05262.11 CDJ39702.1 - 0.22 10.0 13.2 0.26 9.7 13.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Hamartin PF04388.12 CDJ39702.1 - 0.34 9.5 5.8 0.36 9.5 5.8 1.1 1 0 0 1 1 1 0 Hamartin protein TP53IP5 PF15331.6 CDJ39702.1 - 0.66 10.1 7.8 0.88 9.7 7.8 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 TFIIA PF03153.13 CDJ39702.1 - 1.1 9.2 18.2 1.3 8.9 18.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF755 PF05501.11 CDJ39702.1 - 3 8.1 21.3 0.48 10.7 11.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) PA26 PF04636.13 CDJ39702.1 - 3.7 6.4 7.0 5.3 5.8 7.0 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RR_TM4-6 PF06459.12 CDJ39702.1 - 4 7.2 10.3 5.2 6.8 10.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NuiA PF07924.11 CDJ39702.1 - 5.3 7.5 6.3 0.51 10.7 0.4 2.1 1 1 1 2 2 2 0 Nuclease A inhibitor-like protein GBP_C PF02841.14 CDJ39702.1 - 5.8 6.2 22.4 12 5.2 22.4 1.5 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Roughex PF06020.11 CDJ39702.1 - 6.1 5.8 8.8 9.6 5.2 8.8 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Peptidase_S64 PF08192.11 CDJ39702.1 - 7.1 5.0 8.5 8.4 4.7 8.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 CDJ39702.1 - 8.8 3.3 11.3 9.6 3.2 11.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MBOAT PF03062.19 CDJ39703.1 - 1.5e-22 80.4 26.2 2.7e-22 79.6 18.6 2.1 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CDJ39703.1 - 1.6e-05 25.0 5.2 6.2e-05 23.2 5.2 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family TFIIA PF03153.13 CDJ39703.1 - 0.25 11.3 30.8 0.35 10.8 30.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 CDJ39703.1 - 0.32 9.9 24.6 0.53 9.2 24.6 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RR_TM4-6 PF06459.12 CDJ39703.1 - 3.3 7.5 14.9 0.031 14.1 5.4 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Ctr PF04145.15 CDJ39703.1 - 3.6 8.2 5.8 5.8 7.5 1.4 3.2 2 0 0 2 2 2 0 Ctr copper transporter family Neur_chan_memb PF02932.16 CDJ39703.1 - 3.9 7.5 7.0 12 5.8 7.0 1.9 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Exonuc_VII_L PF02601.15 CDJ39703.1 - 4.4 6.8 19.9 11 5.4 19.9 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Borrelia_P83 PF05262.11 CDJ39703.1 - 5 5.5 14.1 9.1 4.6 14.1 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Mem_trans PF03547.18 CDJ39704.1 - 0.35 9.2 2.8 0.53 8.6 2.8 1.3 1 0 0 1 1 1 0 Membrane transport protein ARA70 PF12489.8 CDJ39704.1 - 2.7 8.2 13.5 4.6 7.4 1.9 2.4 2 1 0 2 2 2 0 Nuclear coactivator CENP-N PF05238.13 CDJ39705.1 - 0.32 10.3 15.3 0.34 10.2 15.3 1.0 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Vfa1 PF08432.10 CDJ39705.1 - 3.7 7.9 22.8 4.6 7.5 22.8 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Membralin PF09746.9 CDJ39705.1 - 4.1 6.4 15.5 4.3 6.3 15.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF737 PF05300.11 CDJ39705.1 - 6.1 7.1 28.4 7.2 6.9 28.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) HemX PF04375.14 CDJ39705.1 - 7.1 5.8 55.0 8.1 5.6 55.0 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase GvpL_GvpF PF06386.11 CDJ39705.1 - 7.3 6.4 19.0 11 5.9 19.0 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Pal1 PF08316.11 CDJ39705.1 - 9 7.1 7.1 14 6.4 7.1 1.4 1 0 0 1 1 1 0 Pal1 cell morphology protein Exonuc_VII_L PF02601.15 CDJ39705.1 - 9.3 5.7 33.1 10 5.6 33.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit GAS PF13851.6 CDJ39706.1 - 0.012 15.0 13.3 0.013 14.9 13.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 CDJ39706.1 - 0.015 15.9 3.2 0.015 15.9 3.2 2.1 1 1 1 2 2 2 0 Initiation control protein YabA COG5 PF10392.9 CDJ39706.1 - 0.039 14.1 4.1 0.026 14.7 3.0 1.3 1 1 0 1 1 1 0 Golgi transport complex subunit 5 APG6_N PF17675.1 CDJ39706.1 - 0.07 13.7 15.9 0.19 12.3 15.9 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region RNase_E_G PF10150.9 CDJ39706.1 - 0.1 12.0 4.9 0.12 11.8 4.9 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family Chibby PF14645.6 CDJ39706.1 - 0.18 12.2 4.5 0.51 10.8 4.5 1.8 1 1 0 1 1 1 0 Chibby family DUF5082 PF16888.5 CDJ39706.1 - 0.18 12.1 8.2 0.087 13.1 3.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Filament PF00038.21 CDJ39706.1 - 0.23 11.0 14.1 0.32 10.5 14.1 1.2 1 0 0 1 1 1 0 Intermediate filament protein DUF2514 PF10721.9 CDJ39706.1 - 0.24 11.4 9.6 0.12 12.4 7.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) DUF3450 PF11932.8 CDJ39706.1 - 0.46 9.7 13.8 0.58 9.4 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) WXG100 PF06013.12 CDJ39706.1 - 0.51 10.6 11.5 5.6 7.3 8.5 3.0 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Herpes_UL25 PF01499.16 CDJ39706.1 - 0.81 8.1 7.1 0.79 8.2 7.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family V_ATPase_I PF01496.19 CDJ39706.1 - 1.1 7.1 9.0 1.3 6.9 9.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 CDJ39706.1 - 1.2 7.9 14.6 1.3 7.8 14.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.11 CDJ39706.1 - 5.2 7.4 9.9 12 6.2 3.5 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Pkinase PF00069.25 CDJ39708.1 - 1.9e-22 79.9 0.0 2.4e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CBM_20 PF00686.19 CDJ39708.1 - 9.2e-14 51.1 0.0 1.5e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Starch binding domain Pkinase_Tyr PF07714.17 CDJ39708.1 - 2.4e-12 46.7 0.0 3.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase KaiB PF07689.12 CDJ39708.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 KaiB domain ERO1 PF04137.15 CDJ39709.1 - 6.3e-10 38.8 0.6 7e-10 38.6 0.6 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) NatB_MDM20 PF09797.9 CDJ39709.1 - 0.0033 16.4 4.8 0.0038 16.2 4.8 1.0 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TFIIA PF03153.13 CDJ39709.1 - 2.3 8.1 17.9 2.9 7.8 17.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DivIC PF04977.15 CDJ39709.1 - 7.2 6.5 13.9 1.6 8.5 7.5 2.1 2 0 0 2 2 2 0 Septum formation initiator M16C_assoc PF08367.11 CDJ39710.1 - 4.8e-09 35.7 0.2 6.6e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 Peptidase M16C associated LcrG PF07216.12 CDJ39710.1 - 0.017 15.0 1.7 0.026 14.4 1.2 1.6 1 1 0 1 1 1 0 LcrG protein PI31_Prot_N PF11566.8 CDJ39713.1 - 0.29 10.9 3.2 0.32 10.8 3.2 1.0 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal RAB3GAP2_N PF14655.6 CDJ39716.1 - 0.0087 15.4 0.1 0.009 15.3 0.1 1.0 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Pro-MCH PF05824.12 CDJ39716.1 - 0.049 13.6 0.1 0.065 13.2 0.1 1.3 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) CAP_GLY PF01302.25 CDJ39716.1 - 0.054 13.5 0.0 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 CAP-Gly domain PsbY PF06298.11 CDJ39717.1 - 0.11 12.4 0.7 0.11 12.4 0.7 1.7 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) SBE2 PF17076.5 CDJ39718.1 - 0.98 7.6 2.8 1.4 7.1 2.8 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation AAA_11 PF13086.6 CDJ39719.1 - 0.0073 16.1 5.1 0.012 15.4 5.1 1.3 1 0 0 1 1 1 1 AAA domain NEMO PF11577.8 CDJ39719.1 - 0.008 16.2 12.7 0.018 15.1 12.7 1.5 1 0 0 1 1 1 1 NF-kappa-B essential modulator NEMO Ribosomal_60s PF00428.19 CDJ39719.1 - 0.017 15.7 6.7 0.017 15.7 6.7 4.9 4 1 1 5 5 5 0 60s Acidic ribosomal protein DUF4106 PF13388.6 CDJ39719.1 - 0.18 11.0 12.4 0.28 10.4 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) MFAP1 PF06991.11 CDJ39719.1 - 0.46 10.3 15.8 0.83 9.5 15.8 1.3 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing V_ATPase_I PF01496.19 CDJ39719.1 - 2 6.2 8.9 2.9 5.7 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PIN_2 PF10130.9 CDJ39719.1 - 2.9 8.1 3.8 5.1 7.3 3.8 1.3 1 0 0 1 1 1 0 PIN domain Exonuc_VII_L PF02601.15 CDJ39719.1 - 5.1 6.6 14.3 9.1 5.8 14.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TFIIA PF03153.13 CDJ39720.1 - 0.004 17.2 28.2 0.14 12.2 5.4 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit CLN3 PF02487.17 CDJ39720.1 - 0.004 16.3 0.5 0.2 10.7 0.1 2.1 2 0 0 2 2 2 1 CLN3 protein DUF2722 PF10846.8 CDJ39720.1 - 0.018 14.0 20.2 0.04 12.9 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Connexin PF00029.19 CDJ39720.1 - 0.057 13.2 0.5 5.6 6.6 0.0 2.1 2 0 0 2 2 2 0 Connexin TMEM51 PF15345.6 CDJ39720.1 - 0.069 13.0 16.3 0.22 11.3 0.1 3.3 3 0 0 3 3 3 0 Transmembrane protein 51 DUF3327 PF11806.8 CDJ39720.1 - 0.086 13.5 9.4 0.083 13.6 5.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3327) MAS20 PF02064.15 CDJ39720.1 - 0.089 12.9 0.0 0.089 12.9 0.0 2.6 2 1 0 2 2 1 0 MAS20 protein import receptor SpoIIIAH PF12685.7 CDJ39720.1 - 0.28 11.0 8.0 3.8 7.3 4.9 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF4834 PF16118.5 CDJ39720.1 - 0.3 12.1 11.8 0.42 11.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Hydin_ADK PF17213.3 CDJ39720.1 - 0.49 10.6 6.0 1.3 9.2 0.2 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Neur_chan_memb PF02932.16 CDJ39720.1 - 3.2 7.7 4.6 5.4 7.0 1.4 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.12 CDJ39720.1 - 3.4 7.0 20.8 1.9 7.8 0.2 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF4589 PF15252.6 CDJ39720.1 - 5.8 6.9 9.0 4.7 7.1 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) DUF3402 PF11882.8 CDJ39720.1 - 9.3 5.2 7.6 7.9 5.5 3.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) Spt20 PF12090.8 CDJ39720.1 - 9.3 5.8 40.6 7.5 6.1 12.0 2.2 2 0 0 2 2 2 0 Spt20 family DUF4659 PF15558.6 CDJ39721.1 - 0.11 11.3 48.7 0.15 10.9 48.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4659) Utp14 PF04615.13 CDJ39721.1 - 1.6 7.2 25.9 1.9 7.0 25.9 1.0 1 0 0 1 1 1 0 Utp14 protein DLIC PF05783.11 CDJ39722.1 - 3.5 6.4 11.9 0.18 10.6 0.6 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) SSP160 PF06933.11 CDJ39722.1 - 5.1 5.2 15.0 8.1 4.5 15.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.9 CDJ39723.1 - 7.8e-05 21.4 16.7 0.0001 21.1 16.7 1.1 1 0 0 1 1 1 1 Macoilin family Exonuc_VII_L PF02601.15 CDJ39723.1 - 0.00038 20.1 14.7 0.00038 20.1 14.7 1.5 2 0 0 2 2 2 1 Exonuclease VII, large subunit V_ATPase_I PF01496.19 CDJ39723.1 - 0.026 12.5 16.0 0.035 12.0 16.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ39723.1 - 0.095 12.7 53.8 0.52 10.3 45.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LMBR1 PF04791.16 CDJ39723.1 - 0.2 10.5 3.2 0.27 10.1 3.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein hDGE_amylase PF14701.6 CDJ39723.1 - 1.5 7.8 8.3 2.1 7.3 8.3 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain PX PF00787.24 CDJ39724.1 - 1.9e-13 50.4 0.1 2.1e-13 50.3 0.1 1.0 1 0 0 1 1 1 1 PX domain CCT_2 PF09425.10 CDJ39724.1 - 0.023 14.6 0.1 0.038 13.9 0.1 1.3 1 0 0 1 1 1 0 Divergent CCT motif Presenilin PF01080.17 CDJ39725.1 - 0.0047 15.8 7.1 0.0047 15.8 7.1 1.6 2 0 0 2 2 2 1 Presenilin DUF2052 PF09747.9 CDJ39725.1 - 0.049 13.8 17.0 0.099 12.8 17.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF2828 PF11443.8 CDJ39725.1 - 0.07 11.2 9.0 0.11 10.6 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Dimerisation PF08100.11 CDJ39725.1 - 0.073 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain MRP-S31 PF15433.6 CDJ39725.1 - 0.14 11.8 13.1 0.21 11.2 13.1 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 FAM150 PF15129.6 CDJ39725.1 - 0.21 11.7 15.5 0.52 10.5 2.6 2.4 2 0 0 2 2 2 0 FAM150 family SLC12 PF03522.15 CDJ39725.1 - 0.43 9.6 13.0 0.74 8.8 13.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 TFIIA PF03153.13 CDJ39725.1 - 0.86 9.5 29.5 0.045 13.8 23.8 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.6 CDJ39725.1 - 1.1 9.8 11.3 2.1 8.9 5.4 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein ALMT PF11744.8 CDJ39725.1 - 1.3 7.8 13.3 2.1 7.1 13.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Glyco_transf_41 PF13844.6 CDJ39725.1 - 1.5 7.2 6.4 2.1 6.7 6.4 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 Dicty_REP PF05086.12 CDJ39725.1 - 1.9 6.4 7.1 2.8 5.8 7.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GPCR_chapero_1 PF11904.8 CDJ39725.1 - 3.7 6.9 8.3 7 6.0 8.3 1.4 1 0 0 1 1 1 0 GPCR-chaperone XRN_M PF17846.1 CDJ39725.1 - 3.9 6.3 11.1 5.6 5.8 11.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DUF4407 PF14362.6 CDJ39725.1 - 4.1 6.7 26.7 5.9 6.1 26.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF572 PF04502.13 CDJ39725.1 - 4.2 6.9 15.4 74 2.8 14.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.16 CDJ39725.1 - 5.1 7.1 10.8 1.1 9.2 6.5 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ39725.1 - 5.2 6.8 16.9 0.61 9.9 12.8 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4647 PF15504.6 CDJ39725.1 - 6.6 5.7 16.9 11 5.0 16.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Activator_LAG-3 PF11498.8 CDJ39725.1 - 7.1 5.5 42.0 11 4.8 42.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Hid1 PF12722.7 CDJ39725.1 - 9.8 4.2 15.7 16 3.5 15.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2722 PF10846.8 CDJ39726.1 - 0.0039 16.2 0.2 0.0039 16.2 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DER1 PF04511.15 CDJ39729.1 - 0.0039 17.2 0.0 0.0042 17.0 0.0 1.1 1 0 0 1 1 1 1 Der1-like family Hamartin PF04388.12 CDJ39731.1 - 8 5.0 36.7 11 4.6 36.7 1.0 1 0 0 1 1 1 0 Hamartin protein FH2 PF02181.23 CDJ39733.1 - 4.5e-70 236.7 0.1 5.8e-70 236.3 0.1 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Cir_N PF10197.9 CDJ39733.1 - 6.2 7.1 8.7 0.28 11.4 1.9 2.3 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCCH PF00642.24 CDJ39734.1 - 8.5e-05 22.4 22.1 0.001 18.9 1.6 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ39734.1 - 0.014 15.2 0.7 0.014 15.2 0.7 3.2 4 0 0 4 4 4 0 CCCH-type zinc finger IMCp PF12314.8 CDJ39736.1 - 1.1e-19 70.5 33.0 1.1e-19 70.5 33.0 2.4 2 0 0 2 2 2 1 Inner membrane complex protein SUIM_assoc PF16619.5 CDJ39736.1 - 0.00065 19.7 0.0 0.00065 19.7 0.0 3.8 4 2 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ39736.1 - 0.039 14.0 44.9 0.47 10.4 13.9 2.3 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ39736.1 - 2.1 7.9 30.4 0.63 9.6 9.7 2.4 2 0 0 2 2 2 0 Spt20 family IQCJ-SCHIP1 PF15157.6 CDJ39739.1 - 0.075 12.9 0.2 0.085 12.7 0.2 1.1 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Ribosomal_60s PF00428.19 CDJ39739.1 - 7.4 7.2 17.6 4.2 8.0 10.0 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein CCDC53 PF10152.9 CDJ39740.1 - 0.054 13.9 0.1 0.071 13.5 0.1 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2729 PF10870.8 CDJ39740.1 - 0.19 11.6 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) WD40 PF00400.32 CDJ39741.1 - 6e-13 49.1 3.8 0.011 16.5 0.1 6.6 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ39741.1 - 0.00031 21.0 0.0 0.095 13.0 0.0 3.4 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_20 PF14561.6 CDJ39741.1 - 0.059 13.7 1.8 0.15 12.4 1.8 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PQQ_3 PF13570.6 CDJ39741.1 - 0.17 12.4 0.7 37 5.0 0.0 3.9 3 0 0 3 3 3 0 PQQ-like domain SF1-HH PF16275.5 CDJ39742.1 - 1.7e-25 89.5 0.0 4.4e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CDJ39742.1 - 1e-09 38.1 0.1 1.8e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 CDJ39742.1 - 7.3e-05 22.7 0.8 0.18 11.8 0.3 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 CDJ39742.1 - 0.00066 19.6 8.5 0.014 15.4 0.4 2.7 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ39742.1 - 0.0012 18.5 2.8 0.93 9.3 0.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-RING_9 PF13901.6 CDJ39742.1 - 0.0031 17.5 0.2 0.0051 16.8 0.2 1.2 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon SPX PF03105.19 CDJ39742.1 - 0.17 11.7 8.7 0.33 10.8 8.7 1.4 1 0 0 1 1 1 0 SPX domain zf-CCHC_6 PF15288.6 CDJ39742.1 - 0.43 10.5 10.8 2.2 8.2 0.3 3.3 3 0 0 3 3 3 0 Zinc knuckle zf-LSD1 PF06943.12 CDJ39742.1 - 2.9 7.8 6.7 6.4 6.7 0.2 2.5 2 0 0 2 2 2 0 LSD1 zinc finger DUF2722 PF10846.8 CDJ39743.1 - 0.0017 17.4 9.8 0.0017 17.4 9.8 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) RIFIN PF02009.16 CDJ39743.1 - 0.003 17.5 4.7 0.045 13.6 0.4 2.5 2 0 0 2 2 2 1 Rifin Neur_chan_memb PF02932.16 CDJ39743.1 - 0.004 17.3 6.1 0.029 14.4 1.2 2.3 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region MMR1 PF08505.10 CDJ39743.1 - 0.0071 16.7 18.1 0.25 11.6 3.8 2.4 2 0 0 2 2 2 2 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.17 CDJ39743.1 - 0.012 14.4 13.2 0.012 14.4 1.0 2.3 2 0 0 2 2 2 0 Presenilin Peptidase_S49_N PF08496.10 CDJ39743.1 - 0.023 14.8 9.2 0.16 12.0 3.0 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal FAM76 PF16046.5 CDJ39743.1 - 0.027 13.8 16.6 0.13 11.6 4.3 2.2 2 0 0 2 2 2 0 FAM76 protein DUF4050 PF13259.6 CDJ39743.1 - 0.05 13.9 9.1 0.25 11.6 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) DUF4471 PF14740.6 CDJ39743.1 - 0.078 12.2 9.1 0.029 13.6 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) MecA PF05389.12 CDJ39743.1 - 0.12 12.0 3.9 0.13 11.8 0.3 2.2 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) SR-25 PF10500.9 CDJ39743.1 - 0.13 11.9 34.8 0.36 10.4 17.1 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ39743.1 - 0.13 12.5 0.0 0.13 12.5 0.0 5.4 2 1 3 5 5 4 0 Anti-sigma-K factor rskA eIF-3_zeta PF05091.12 CDJ39743.1 - 0.27 10.2 16.9 0.12 11.3 4.5 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Apt1 PF10351.9 CDJ39743.1 - 0.29 9.9 11.8 0.81 8.5 4.0 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain PAT1 PF09770.9 CDJ39743.1 - 0.3 9.3 29.8 0.45 8.7 17.0 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CPSF100_C PF13299.6 CDJ39743.1 - 0.35 11.0 9.8 0.85 9.8 2.5 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Gti1_Pac2 PF09729.9 CDJ39743.1 - 0.38 10.8 11.2 0.3 11.1 1.2 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family Tim54 PF11711.8 CDJ39743.1 - 0.52 9.0 7.1 0.1 11.4 0.8 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 CDJ39743.1 - 0.7 9.6 9.2 0.073 12.8 1.1 2.2 2 0 0 2 2 2 0 Connexin GPCR_chapero_1 PF11904.8 CDJ39743.1 - 0.76 9.2 6.0 0.54 9.6 0.2 2.2 2 0 0 2 2 2 0 GPCR-chaperone Otopetrin PF03189.13 CDJ39743.1 - 0.94 8.2 5.7 1.2 7.9 0.8 2.1 2 0 0 2 2 2 0 Otopetrin DUF4770 PF15994.5 CDJ39743.1 - 1.3 9.3 15.5 0.34 11.1 6.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Band_3_cyto PF07565.13 CDJ39743.1 - 1.5 8.6 18.1 0.49 10.1 7.8 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FAM60A PF15396.6 CDJ39743.1 - 2.3 8.2 12.3 8.2 6.4 0.7 2.4 2 0 0 2 2 2 0 Protein Family FAM60A Eapp_C PF10238.9 CDJ39743.1 - 3.1 7.9 15.3 0.13 12.3 2.4 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein OATP PF03137.20 CDJ39743.1 - 4.6 5.4 7.1 0.42 8.8 0.6 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family EPL1 PF10513.9 CDJ39743.1 - 5.7 7.3 16.2 2.5 8.5 6.6 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like SelP_N PF04592.14 CDJ39743.1 - 6.6 6.1 36.6 0.098 12.1 21.8 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region RR_TM4-6 PF06459.12 CDJ39743.1 - 8.3 6.1 12.7 0.58 9.9 3.5 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 BRF1 PF07741.13 CDJ39743.1 - 9 6.7 10.8 4.8 7.6 1.3 2.9 2 0 0 2 2 2 0 Brf1-like TBP-binding domain SMN PF06003.12 CDJ39744.1 - 0.024 13.9 10.9 2.5 7.3 0.0 3.9 1 1 2 3 3 3 0 Survival motor neuron protein (SMN) XRN_M PF17846.1 CDJ39744.1 - 0.028 13.4 5.5 0.16 10.9 1.5 2.2 2 0 0 2 2 2 0 Xrn1 helical domain F-112 PF09645.10 CDJ39744.1 - 0.031 14.4 1.0 0.031 14.4 1.0 3.1 3 1 1 4 4 4 0 F-112 protein SAWADEE PF16719.5 CDJ39744.1 - 0.062 13.3 0.1 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 SAWADEE domain DDHD PF02862.17 CDJ39744.1 - 0.33 11.1 9.6 0.26 11.4 2.8 2.2 2 0 0 2 2 2 0 DDHD domain CCDC84 PF14968.6 CDJ39744.1 - 8.6 5.9 12.5 1.6 8.2 5.8 2.0 2 0 0 2 2 2 0 Coiled coil protein 84 Pkinase PF00069.25 CDJ39745.1 - 0.016 14.5 3.4 0.023 14.1 0.1 2.5 2 1 1 3 3 3 0 Protein kinase domain YlqD PF11068.8 CDJ39745.1 - 7 7.0 17.6 11 6.4 17.6 1.2 1 0 0 1 1 1 0 YlqD protein TPR_1 PF00515.28 CDJ39746.1 - 6.7e-51 168.1 25.3 7e-09 35.1 0.0 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ39746.1 - 7.5e-40 131.8 25.0 2.3e-06 27.3 2.1 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ39746.1 - 7.2e-26 89.6 10.4 9.1e-09 34.9 1.9 6.7 5 1 1 6 6 6 5 TPR repeat TPR_8 PF13181.6 CDJ39746.1 - 1.2e-21 75.0 21.5 0.0042 17.2 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ39746.1 - 1.7e-19 69.9 10.0 9.4e-11 41.9 0.5 6.3 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ39746.1 - 6.4e-17 60.8 9.9 0.11 13.3 0.4 8.9 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ39746.1 - 4.9e-16 59.1 17.1 0.00067 20.3 0.3 7.3 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ39746.1 - 3.6e-12 45.4 4.8 0.0021 18.0 0.1 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ39746.1 - 2.3e-10 40.1 15.3 0.028 14.8 0.3 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ39746.1 - 3.3e-10 39.5 9.5 0.072 13.0 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat STI1 PF17830.1 CDJ39746.1 - 5.6e-09 35.8 5.8 2.9e-07 30.3 2.8 6.4 3 1 3 6 6 2 2 STI1 domain TPR_9 PF13371.6 CDJ39746.1 - 1e-07 32.0 0.0 0.0048 17.0 0.0 7.4 4 2 2 8 8 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ39746.1 - 3.8e-06 26.9 11.2 0.27 11.3 0.0 6.6 5 1 1 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 CDJ39746.1 - 0.00087 19.8 8.5 6 7.7 0.2 6.4 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR PF01535.20 CDJ39746.1 - 0.032 14.5 3.8 0.28 11.5 0.2 3.4 3 0 0 3 3 3 0 PPR repeat PPR_2 PF13041.6 CDJ39746.1 - 0.33 11.2 1.9 10 6.4 0.2 2.7 2 0 0 2 2 2 0 PPR repeat family Ribosomal_S17 PF00366.20 CDJ39747.1 - 1.9e-12 47.1 0.0 3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 His_Phos_1 PF00300.22 CDJ39749.1 - 2.1e-44 151.5 0.0 2.9e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 CDJ39749.1 - 0.046 13.1 0.0 0.094 12.0 0.0 1.4 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Ribosomal_S17e PF00833.18 CDJ39750.1 - 6.8e-60 200.4 1.8 7.7e-60 200.2 1.8 1.0 1 0 0 1 1 1 1 Ribosomal S17 SpoIIE PF07228.12 CDJ39751.1 - 1.1e-06 28.7 0.5 0.031 14.2 0.1 3.0 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) CDC45 PF02724.14 CDJ39751.1 - 1.1 7.5 26.6 0.014 13.8 4.1 2.3 2 0 0 2 2 2 0 CDC45-like protein DUF913 PF06025.12 CDJ39751.1 - 5.9 5.8 20.4 0.037 13.0 1.6 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Abhydrolase_6 PF12697.7 CDJ39752.1 - 4.5e-12 47.0 15.9 2.9e-11 44.4 15.9 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ39752.1 - 3.2e-11 43.0 0.1 1.5e-05 24.4 0.2 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ39752.1 - 4.9e-06 26.4 1.4 0.00028 20.6 0.3 2.8 3 0 0 3 3 3 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CDJ39752.1 - 0.0074 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Tir_receptor_N PF07490.11 CDJ39752.1 - 0.07 13.0 0.8 0.12 12.2 0.8 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Collagen PF01391.18 CDJ39752.1 - 0.44 10.3 15.6 0.5 10.2 4.7 2.6 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) PHD PF00628.29 CDJ39753.1 - 0.00074 19.4 3.3 0.00074 19.4 3.3 4.0 4 0 0 4 4 4 1 PHD-finger zf-MIZ PF02891.20 CDJ39754.1 - 6.1e-10 38.7 2.4 1.5e-06 27.8 0.1 3.0 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger Ank_2 PF12796.7 CDJ39755.1 - 1.7e-23 83.0 0.1 2.5e-09 37.6 0.1 3.7 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ39755.1 - 1.5e-20 73.3 1.9 7.4e-10 39.2 0.1 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ39755.1 - 2.4e-20 70.5 0.3 5.7e-05 23.2 0.1 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CDJ39755.1 - 6.9e-19 67.7 2.7 1.2e-06 28.7 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CDJ39755.1 - 2.9e-18 65.4 0.9 0.00023 21.5 0.2 4.8 4 0 0 4 4 4 4 Ankyrin repeat Pex14_N PF04695.13 CDJ39755.1 - 0.23 12.1 10.8 0.034 14.8 6.6 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GREB1 PF15782.5 CDJ39755.1 - 6 3.9 12.8 7.6 3.5 12.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AF-4 PF05110.13 CDJ39755.1 - 7.2 4.6 21.8 9.4 4.2 21.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TP6A_N PF04406.14 CDJ39756.1 - 7e-11 42.0 0.1 1.3e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Orthopox_A36R PF05950.11 CDJ39756.1 - 0.062 13.5 0.1 2.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Orthopoxvirus A36R protein Sdh5 PF03937.16 CDJ39757.1 - 7.7e-16 57.8 0.0 1.3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Aldo_ket_red PF00248.21 CDJ39758.1 - 4.7e-30 104.8 0.0 2.4e-27 95.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family LCM PF04072.14 CDJ39759.1 - 3.4e-26 92.4 0.1 1.8e-24 86.7 0.0 2.5 2 1 0 2 2 2 2 Leucine carboxyl methyltransferase Orthopox_A5L PF06193.11 CDJ39759.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like OAR PF03826.17 CDJ39760.1 - 0.082 12.8 1.8 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 OAR domain AP2 PF00847.20 CDJ39761.1 - 2.8e-10 40.3 1.2 2.8e-10 40.3 1.2 2.0 2 0 0 2 2 2 1 AP2 domain NifU_N PF01592.16 CDJ39762.1 - 4.9e-48 162.5 0.1 6e-48 162.2 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Sec1 PF00995.23 CDJ39763.1 - 9.2e-69 233.2 0.0 6.3e-68 230.4 0.0 1.9 1 1 0 1 1 1 1 Sec1 family UPF0121 PF03661.13 CDJ39764.1 - 6.7e-12 45.3 0.7 1.2e-11 44.5 0.7 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Ephrin_rec_like PF07699.13 CDJ39765.1 - 9.4e-30 102.1 115.3 1.4e-08 34.4 2.9 11.3 11 1 0 11 11 11 8 Putative ephrin-receptor like PAN_4 PF14295.6 CDJ39765.1 - 0.00086 19.2 1.0 0.0055 16.6 1.0 2.6 1 0 0 1 1 1 1 PAN domain Uso1_p115_C PF04871.13 CDJ39765.1 - 0.012 15.9 4.3 0.025 14.9 4.3 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HALZ PF02183.18 CDJ39765.1 - 0.098 12.9 1.1 0.19 12.0 1.1 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper He_PIG PF05345.12 CDJ39765.1 - 0.48 10.7 2.3 1 9.6 0.3 2.7 2 0 0 2 2 2 0 Putative Ig domain EGF_MSP1_1 PF12946.7 CDJ39765.1 - 1.8 8.7 20.4 8.4 6.5 0.3 7.0 6 0 0 6 6 6 0 MSP1 EGF domain 1 RabGAP-TBC PF00566.18 CDJ39766.1 - 2.3e-33 115.7 0.1 2.3e-33 115.7 0.1 3.0 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 CDJ39766.1 - 0.016 15.8 0.0 0.064 13.8 0.0 2.0 1 0 0 1 1 1 0 Rhodanese-like domain PIG-S PF10510.9 CDJ39766.1 - 7.4 5.3 12.5 0.61 8.9 5.1 2.5 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein RRM_1 PF00076.22 CDJ39767.1 - 9e-17 60.7 0.3 2.5e-16 59.2 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 CDJ39767.1 - 2.5e-13 50.5 0.2 4.4e-13 49.7 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G PHM7_cyt PF14703.6 CDJ39767.1 - 0.015 15.6 0.6 21 5.3 0.1 3.3 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter DA1-like PF12315.8 CDJ39769.1 - 4.1e-13 49.2 0.3 7.7e-13 48.3 0.3 1.4 1 0 0 1 1 1 1 Protein DA1 LIM PF00412.22 CDJ39769.1 - 0.071 13.4 0.1 0.071 13.4 0.1 5.1 4 1 1 5 5 5 0 LIM domain Spt5-NGN PF03439.13 CDJ39769.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section EF-hand_6 PF13405.6 CDJ39770.1 - 5.1e-05 22.9 0.1 7e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CDJ39770.1 - 0.00024 21.5 0.1 0.0003 21.2 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ39770.1 - 0.00038 19.8 0.2 0.00054 19.3 0.2 1.3 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 CDJ39770.1 - 0.00075 18.9 0.3 0.0011 18.3 0.3 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CDJ39770.1 - 0.0049 16.7 0.1 0.0069 16.2 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair Ribosomal_S17_N PF16205.5 CDJ39771.1 - 9.9e-29 99.5 0.2 1.9e-28 98.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CDJ39771.1 - 3e-23 81.7 1.5 4.5e-23 81.1 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 EELM2 PF15863.5 CDJ39772.1 - 3.9e-78 261.5 0.1 5.7e-78 260.9 0.1 1.2 1 0 0 1 1 1 1 Extended EGL-27 and MTA1 homology domain PHD PF00628.29 CDJ39772.1 - 5.7e-09 35.7 6.8 5.7e-09 35.7 6.8 1.9 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 CDJ39772.1 - 0.0028 17.3 3.8 0.079 12.6 3.2 2.7 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain zf-RanBP PF00641.18 CDJ39772.1 - 0.035 13.4 0.5 0.46 9.8 0.1 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others WD40_4 PF16300.5 CDJ39773.1 - 2.1e-19 69.1 0.0 4.2e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CDJ39773.1 - 2.8e-14 53.3 5.4 1.1e-06 29.2 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ39773.1 - 8.6e-10 38.8 0.0 0.001 19.3 0.1 4.2 4 1 1 5 5 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 CDJ39773.1 - 4.4e-07 29.7 0.0 9.5e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Shugoshin_N PF07558.11 CDJ39773.1 - 0.00078 19.3 0.7 0.21 11.5 0.1 2.7 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Nup160 PF11715.8 CDJ39773.1 - 0.0094 14.6 0.0 0.027 13.1 0.1 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.11 CDJ39773.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A BLOC1_2 PF10046.9 CDJ39773.1 - 0.045 14.0 19.0 0.35 11.2 4.9 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ge1_WD40 PF16529.5 CDJ39773.1 - 0.095 11.6 0.3 1.4 7.8 0.0 2.9 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF812 PF05667.11 CDJ39773.1 - 0.21 10.4 19.2 0.39 9.6 19.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ABC_tran_CTD PF16326.5 CDJ39773.1 - 0.29 11.4 26.2 0.14 12.4 13.6 3.6 1 1 2 3 3 3 0 ABC transporter C-terminal domain DUF3015 PF11220.8 CDJ39773.1 - 0.32 10.9 1.7 0.52 10.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3015) Lebercilin PF15619.6 CDJ39773.1 - 0.38 10.4 30.0 1.5 8.5 13.0 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Nop16 PF09420.10 CDJ39773.1 - 0.43 10.6 14.0 0.77 9.8 14.0 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 DUF3584 PF12128.8 CDJ39773.1 - 0.5 7.8 20.9 0.68 7.4 20.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 CDJ39773.1 - 0.66 10.4 27.4 0.054 13.9 8.4 2.1 1 1 1 2 2 2 0 Fez1 Atg14 PF10186.9 CDJ39773.1 - 1.1 8.3 18.8 1.7 7.7 18.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin_1 PF12718.7 CDJ39773.1 - 1.4 9.1 30.1 4.4 7.4 29.7 1.9 1 1 1 2 2 2 0 Tropomyosin like Noelin-1 PF12308.8 CDJ39773.1 - 1.7 8.7 7.3 0.81 9.7 0.8 2.5 1 1 2 3 3 3 0 Neurogenesis glycoprotein GAS PF13851.6 CDJ39773.1 - 2.9 7.2 28.8 12 5.2 28.3 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 CDJ39773.1 - 3 6.4 17.7 4.2 5.9 17.7 1.1 1 0 0 1 1 1 0 AAA domain TolA_bind_tri PF16331.5 CDJ39773.1 - 4.1 7.6 19.1 2.8 8.1 8.0 3.1 2 1 1 3 3 3 0 TolA binding protein trimerisation LMBR1 PF04791.16 CDJ39773.1 - 4.4 6.1 10.2 6 5.7 10.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TSC22 PF01166.18 CDJ39773.1 - 5.1 7.5 7.5 2.9 8.3 0.4 3.2 1 1 2 3 3 3 0 TSC-22/dip/bun family V_ATPase_I PF01496.19 CDJ39773.1 - 9.4 4.0 13.6 15 3.3 13.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF853 PF05872.12 CDJ39774.1 - 0.12 10.9 1.6 0.2 10.2 1.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) CAF1C_H4-bd PF12265.8 CDJ39775.1 - 1.2e-17 63.9 0.6 3.4e-17 62.5 0.6 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CDJ39775.1 - 3.9e-12 46.5 8.1 0.082 13.8 0.5 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ39775.1 - 0.00042 20.6 0.1 0.7 10.2 0.0 3.9 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ciart PF15673.5 CDJ39775.1 - 0.042 13.2 0.1 0.065 12.6 0.1 1.3 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor V-ATPase_G PF03179.15 CDJ39777.1 - 4.7e-25 88.2 9.0 5.6e-25 87.9 9.0 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 CDJ39777.1 - 0.082 13.0 11.0 0.039 14.0 8.5 1.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) PEP-utilisers_N PF05524.13 CDJ39777.1 - 0.58 10.3 5.6 0.87 9.8 5.6 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal WD40 PF00400.32 CDJ39778.1 - 4.3e-22 78.0 16.3 2e-05 25.2 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ39778.1 - 1.3e-06 28.6 0.0 1.3 9.4 0.0 4.9 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ39778.1 - 0.3 10.0 0.5 37 3.1 0.2 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_S5 PF00333.20 CDJ39779.1 - 1.4e-29 101.9 0.4 3.1e-29 100.7 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CDJ39779.1 - 1.9e-23 81.7 0.0 3.5e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 CDJ39779.1 - 4.1 8.0 9.7 9.7 6.8 9.7 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 BAG6 PF12057.8 CDJ39780.1 - 0.038 13.7 0.1 5.1 6.8 0.0 2.6 1 1 1 2 2 2 0 BCL2-associated athanogene 6 PRP1_N PF06424.12 CDJ39781.1 - 1.5e-52 178.0 3.2 2.1e-43 148.2 0.6 3.0 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 CDJ39781.1 - 4.4e-30 101.8 31.2 0.0011 19.7 0.4 15.2 5 3 9 15 15 15 8 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ39781.1 - 3.7e-20 72.2 13.4 0.00042 20.8 0.2 9.4 7 3 3 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ39781.1 - 2.7e-08 34.3 15.8 0.00026 21.6 0.0 8.7 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ39781.1 - 4.3e-06 26.5 2.7 12 6.4 0.0 7.8 9 1 1 10 10 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ39781.1 - 5.6e-06 26.1 17.5 5.1 7.5 0.2 10.5 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ39781.1 - 1.3e-05 25.2 5.2 2.9 8.5 0.0 9.4 11 2 1 12 12 11 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ39781.1 - 6.3e-05 22.6 0.3 1.7 8.4 0.0 4.8 4 0 0 4 4 4 2 TPR repeat ANAPC3 PF12895.7 CDJ39781.1 - 9.5e-05 22.5 6.1 0.22 11.8 0.3 5.5 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDJ39781.1 - 0.0015 18.8 11.4 1.5 9.1 0.2 7.0 6 1 1 7 7 7 1 Tetratricopeptide repeat ChAPs PF09295.10 CDJ39781.1 - 0.002 17.2 8.3 0.73 8.8 0.1 4.1 2 1 2 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) Suf PF05843.14 CDJ39781.1 - 0.0025 17.9 0.2 17 5.3 0.1 4.7 4 2 1 5 5 5 0 Suppressor of forked protein (Suf) DUF3808 PF10300.9 CDJ39781.1 - 0.0073 15.1 3.1 0.69 8.6 0.1 4.2 4 1 1 5 5 5 1 Protein of unknown function (DUF3808) TPR_9 PF13371.6 CDJ39781.1 - 0.018 15.2 8.9 0.55 10.4 0.1 5.5 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ39781.1 - 0.021 15.4 12.6 32 5.5 0.0 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_21 PF09976.9 CDJ39781.1 - 0.023 14.4 14.5 0.014 15.1 3.3 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat-like domain HHH PF00633.23 CDJ39781.1 - 0.035 14.0 0.3 0.21 11.5 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif SCAN PF02023.17 CDJ39781.1 - 0.099 12.5 4.1 2.3 8.1 0.1 3.9 2 1 1 3 3 3 0 SCAN domain TPR_1 PF00515.28 CDJ39781.1 - 0.36 10.7 1.7 3.5 7.6 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 CDJ39782.1 - 5.9e-40 137.9 0.6 3.7e-29 102.3 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ39782.1 - 4.4e-12 46.0 0.9 1.6e-11 44.3 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CDJ39782.1 - 7.5e-07 28.6 3.6 1.8e-06 27.3 3.6 1.7 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CDJ39782.1 - 3.4e-06 26.7 0.2 8e-06 25.5 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDJ39782.1 - 9.5e-06 25.0 0.1 1.8e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDJ39782.1 - 1.6e-05 24.7 0.2 4.6e-05 23.2 0.2 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CDJ39782.1 - 0.00015 21.1 0.4 0.0003 20.2 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CDJ39782.1 - 0.0005 19.4 0.1 0.0016 17.8 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 CDJ39782.1 - 0.0012 19.3 0.3 0.0034 17.9 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ39782.1 - 0.0031 16.3 0.8 0.0031 16.3 0.8 2.2 2 1 1 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 CDJ39782.1 - 0.0034 16.7 1.2 0.0091 15.3 1.2 1.7 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CDJ39782.1 - 0.0069 15.5 1.8 0.013 14.6 1.8 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A PHD PF00628.29 CDJ39782.1 - 0.12 12.3 8.4 0.016 15.1 1.5 2.9 3 0 0 3 3 3 0 PHD-finger Ribosomal_S3_C PF00189.20 CDJ39783.1 - 4.8e-23 81.5 1.2 2.1e-22 79.5 1.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CDJ39783.1 - 5.3e-11 42.2 0.0 8.4e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 CDJ39783.1 - 0.13 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Ank_4 PF13637.6 CDJ39785.1 - 7.7e-10 39.1 6.9 0.001 19.6 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ39785.1 - 7.2e-07 29.4 3.6 0.0056 17.0 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ39785.1 - 9.4e-07 29.3 7.8 0.26 11.9 0.0 6.1 5 0 0 5 5 5 2 Ankyrin repeats (3 copies) LRR_8 PF13855.6 CDJ39785.1 - 1.7e-05 24.5 3.2 1.7e-05 24.5 3.2 2.9 3 0 0 3 3 3 1 Leucine rich repeat Ank PF00023.30 CDJ39785.1 - 4.1e-05 23.8 6.4 0.049 14.1 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 CDJ39785.1 - 0.0071 16.8 8.8 2.2 9.1 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat Bromodomain PF00439.25 CDJ39786.1 - 6.3e-13 48.6 0.0 1.5e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain SPX PF03105.19 CDJ39787.1 - 0.0011 18.9 12.9 0.0019 18.2 12.9 1.4 1 0 0 1 1 1 1 SPX domain Ribosomal_60s PF00428.19 CDJ39787.1 - 3.1 8.5 19.8 6.4 7.4 11.3 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPPII_N PF12583.8 CDJ39789.1 - 0.0033 18.0 4.1 0.0041 17.7 4.1 1.0 1 0 0 1 1 1 1 Tripeptidyl peptidase II N terminal DUF1068 PF06364.12 CDJ39789.1 - 0.0069 16.3 1.9 0.0077 16.1 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1068) SR-25 PF10500.9 CDJ39789.1 - 0.071 12.7 11.3 0.083 12.5 11.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein POM121 PF15229.6 CDJ39790.1 - 0.44 10.2 21.5 0.54 9.9 21.5 1.1 1 0 0 1 1 1 0 POM121 family Dehydrin PF00257.19 CDJ39790.1 - 1.5 9.3 17.5 2.3 8.7 17.5 1.3 1 0 0 1 1 1 0 Dehydrin PAP1 PF08601.10 CDJ39790.1 - 4 7.1 23.9 4.6 6.9 23.9 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 SR-25 PF10500.9 CDJ39790.1 - 4.8 6.7 27.1 5.9 6.4 27.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spem1 PF15670.5 CDJ39790.1 - 5.1 6.6 12.3 5.7 6.4 12.3 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 BORG_CEP PF14957.6 CDJ39790.1 - 5.5 8.2 17.0 6.5 7.9 17.0 1.0 1 0 0 1 1 1 0 Cdc42 effector FAM60A PF15396.6 CDJ39790.1 - 6 6.8 13.1 6.5 6.7 13.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Membralin PF09746.9 CDJ39790.1 - 6.4 5.7 9.3 6.2 5.7 9.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein Tim54 PF11711.8 CDJ39790.1 - 7.1 5.3 13.8 8.2 5.1 13.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 CDJ39790.1 - 7.2 6.3 8.1 8 6.1 8.1 1.1 1 0 0 1 1 1 0 Connexin TERB2 PF15101.6 CDJ39790.1 - 8.9 6.3 16.6 11 6.0 16.6 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Macoilin PF09726.9 CDJ39790.1 - 9.5 4.6 20.4 9.7 4.6 20.4 1.0 1 0 0 1 1 1 0 Macoilin family PGA2 PF07543.12 CDJ39792.1 - 0.089 12.8 0.5 6.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein trafficking PGA2 Pkinase PF00069.25 CDJ39793.1 - 4.3e-06 26.3 1.4 6.6e-05 22.4 0.0 2.8 2 2 1 3 3 3 1 Protein kinase domain Methyltransf_34 PF11312.8 CDJ39793.1 - 0.64 9.2 20.1 0.6 9.3 4.9 2.6 1 1 1 2 2 2 0 Putative SAM-dependent methyltransferase DUF812 PF05667.11 CDJ39793.1 - 0.7 8.7 19.1 1 8.2 19.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Peptidase_M3 PF01432.20 CDJ39794.1 - 0.38 10.0 4.1 0.73 9.0 4.1 1.3 1 0 0 1 1 1 0 Peptidase family M3 PDEase_I PF00233.19 CDJ39796.1 - 0.03 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Ribosomal_60s PF00428.19 CDJ39796.1 - 0.09 13.4 1.6 0.13 12.8 1.6 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein LPP PF04728.13 CDJ39796.1 - 0.31 11.5 3.9 0.42 11.0 3.9 1.2 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF3824 PF12868.7 CDJ39796.1 - 2 9.1 4.2 3.5 8.3 4.2 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) SET PF00856.28 CDJ39798.1 - 0.0045 17.4 0.0 0.011 16.2 0.0 1.8 1 1 0 1 1 1 1 SET domain VHS PF00790.19 CDJ39799.1 - 3.2e-08 33.5 0.0 0.00057 19.7 0.0 2.2 2 0 0 2 2 2 2 VHS domain Pro-rich PF15240.6 CDJ39801.1 - 0.019 15.2 34.8 0.026 14.8 34.8 1.1 1 0 0 1 1 1 0 Proline-rich MRI PF15325.6 CDJ39801.1 - 2.9 9.0 7.7 1.5 10.0 5.2 1.8 1 1 0 1 1 1 0 Modulator of retrovirus infection DivIC PF04977.15 CDJ39802.1 - 0.36 10.6 6.9 0.54 10.1 6.9 1.2 1 0 0 1 1 1 0 Septum formation initiator Spt20 PF12090.8 CDJ39802.1 - 1.3 8.6 12.3 1.6 8.3 12.3 1.1 1 0 0 1 1 1 0 Spt20 family TMEM171 PF15471.6 CDJ39803.1 - 0.19 10.7 2.8 0.23 10.4 2.8 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 CCDC24 PF15669.5 CDJ39803.1 - 0.83 9.5 10.7 4.4 7.1 10.7 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Sox_N PF12444.8 CDJ39803.1 - 1.1 10.4 9.8 14 6.9 0.2 2.3 2 0 0 2 2 2 0 Sox developmental protein N terminal Peptidase_S64 PF08192.11 CDJ39803.1 - 1.2 7.6 6.4 1.4 7.3 6.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF4551 PF15087.6 CDJ39803.1 - 1.5 7.5 10.9 1.8 7.3 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ribosomal_60s PF00428.19 CDJ39803.1 - 2.6 8.7 11.0 17 6.1 0.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ39803.1 - 4.9 6.7 13.6 1 8.9 4.5 2.0 2 0 0 2 2 2 0 Spt20 family DUF4808 PF16066.5 CDJ39803.1 - 5.7 7.5 7.1 8.2 7.0 6.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4808) Utp14 PF04615.13 CDJ39804.1 - 0.22 10.0 38.3 0.27 9.8 38.3 1.1 1 0 0 1 1 1 0 Utp14 protein TRAP_alpha PF03896.16 CDJ39804.1 - 8.9 5.4 10.7 7.8 5.6 4.3 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_E_B PF04042.16 CDJ39805.1 - 1.4e-18 67.1 0.0 2.8e-18 66.0 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B NRBF2 PF08961.10 CDJ39805.1 - 0.049 13.2 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DUF2057 PF09829.9 CDJ39805.1 - 0.12 12.6 3.3 11 6.1 1.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Ribosomal_S6 PF01250.17 CDJ39806.1 - 1.6e-05 25.1 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6 Spt20 PF12090.8 CDJ39806.1 - 0.23 11.1 8.6 0.51 9.9 8.6 1.6 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ39806.1 - 0.52 9.2 20.0 0.88 8.5 20.0 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ribosomal_60s PF00428.19 CDJ39807.1 - 7.1 7.3 13.4 0.24 12.0 4.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein KH_1 PF00013.29 CDJ39808.1 - 1.1e-17 63.5 1.3 9.6e-08 31.7 0.6 3.1 2 1 0 2 2 2 2 KH domain KH_2 PF07650.17 CDJ39808.1 - 0.00045 20.0 0.1 0.21 11.4 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 CDJ39808.1 - 0.029 14.5 0.8 7 6.8 0.0 2.9 3 0 0 3 3 3 0 NusA-like KH domain Spt20 PF12090.8 CDJ39809.1 - 1.3 8.6 10.9 1.8 8.1 10.9 1.4 1 0 0 1 1 1 0 Spt20 family CPSF100_C PF13299.6 CDJ39810.1 - 0.53 10.5 10.4 0.98 9.6 2.8 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Sec16 PF12932.7 CDJ39810.1 - 8.6 7.0 7.8 2.1 9.0 0.0 2.9 3 1 0 3 3 3 0 Vesicle coat trafficking protein Sec16 mid-region Spt20 PF12090.8 CDJ39811.1 - 0.21 11.2 28.3 0.31 10.6 15.5 2.5 3 0 0 3 3 3 0 Spt20 family SR-25 PF10500.9 CDJ39811.1 - 1.3 8.5 15.5 0.13 11.8 9.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ39811.1 - 1.4 7.8 23.1 0.33 9.9 11.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ39811.1 - 1.7 8.8 29.3 0.76 9.9 11.5 3.5 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TCP PF03634.13 CDJ39811.1 - 5.5 7.5 16.7 11 6.5 9.2 2.7 2 0 0 2 2 2 0 TCP family transcription factor EPL1 PF10513.9 CDJ39811.1 - 9.5 6.6 9.9 4.1 7.8 4.2 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like ANAPC4_WD40 PF12894.7 CDJ39813.1 - 5.2e-05 23.5 0.0 0.0011 19.2 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 CDJ39813.1 - 0.0088 15.3 0.1 2.9 7.0 0.0 2.5 1 1 1 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 CDJ39813.1 - 0.01 16.7 2.3 18 6.4 1.5 3.9 4 1 0 4 4 4 1 WD domain, G-beta repeat PQQ_2 PF13360.6 CDJ39813.1 - 0.014 15.0 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 PQQ-like domain Lgl_C PF08596.10 CDJ39813.1 - 0.031 13.0 0.1 0.057 12.1 0.0 1.3 1 1 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal SR-25 PF10500.9 CDJ39813.1 - 0.64 9.6 3.5 0.91 9.1 3.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Actin PF00022.19 CDJ39814.1 - 9.2e-11 41.0 0.0 4.4e-09 35.5 0.0 2.0 2 0 0 2 2 2 2 Actin IQCJ-SCHIP1 PF15157.6 CDJ39814.1 - 0.31 10.9 1.8 0.41 10.5 1.8 1.2 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif SR-25 PF10500.9 CDJ39814.1 - 1.7 8.2 10.1 2.3 7.8 10.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RRM_1 PF00076.22 CDJ39815.1 - 3.3e-19 68.5 0.0 4.3e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CDJ39815.1 - 0.0025 17.8 0.3 0.0054 16.7 0.3 1.6 1 1 0 1 1 1 1 RNA binding domain CBM_20 PF00686.19 CDJ39816.1 - 0.0018 18.1 0.0 0.0018 18.1 0.0 1.0 1 0 0 1 1 1 1 Starch binding domain WD40 PF00400.32 CDJ39817.1 - 6.6e-06 26.8 4.2 0.097 13.6 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ39817.1 - 5.5e-05 23.4 0.0 0.0063 16.8 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain ATP_bind_3 PF01171.20 CDJ39819.1 - 9.1e-11 41.8 0.0 9.1e-11 41.8 0.0 2.3 2 1 0 2 2 2 1 PP-loop family DDHD PF02862.17 CDJ39819.1 - 0.049 13.8 10.5 0.21 11.7 6.8 2.5 2 0 0 2 2 2 0 DDHD domain Cwf_Cwc_15 PF04889.12 CDJ39819.1 - 0.055 13.2 16.6 0.8 9.4 7.0 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CCSAP PF15748.5 CDJ39819.1 - 0.32 11.1 30.1 0.14 12.4 24.2 2.5 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Nop53 PF07767.11 CDJ39819.1 - 0.33 10.3 21.3 0.042 13.2 13.5 2.4 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Spt20 PF12090.8 CDJ39819.1 - 0.42 10.2 38.8 1.8 8.2 3.1 2.3 2 0 0 2 2 2 0 Spt20 family Methyltransf_12 PF08242.12 CDJ39819.1 - 2.7 8.8 4.2 3.6 8.4 0.8 2.4 2 0 0 2 2 2 0 Methyltransferase domain RR_TM4-6 PF06459.12 CDJ39819.1 - 2.9 7.7 19.6 1.5 8.6 13.6 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ39819.1 - 4.8 6.1 16.9 0.72 8.8 11.5 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MMR1 PF08505.10 CDJ39819.1 - 8.9 6.5 26.8 2 8.6 20.4 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DcrB PF08786.11 CDJ39820.1 - 0.0013 18.8 4.0 0.0026 17.9 4.0 1.4 1 0 0 1 1 1 1 DcrB MerR-DNA-bind PF09278.11 CDJ39820.1 - 0.4 11.3 10.5 1.3 9.6 10.5 1.9 1 0 0 1 1 1 0 MerR, DNA binding Spt20 PF12090.8 CDJ39820.1 - 3.9 7.0 11.2 5.7 6.5 11.2 1.2 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ39820.1 - 4.6 7.5 27.7 20 5.4 27.5 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA HemY_N PF07219.13 CDJ39821.1 - 0.029 14.6 7.7 0.029 14.6 7.7 3.3 3 0 0 3 3 3 0 HemY protein N-terminus Tom37_C PF11801.8 CDJ39821.1 - 0.055 13.4 0.7 0.055 13.4 0.7 1.9 2 1 0 2 2 2 0 Tom37 C-terminal domain GST_C_6 PF17171.4 CDJ39821.1 - 0.095 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2135 PF09906.9 CDJ39821.1 - 0.13 12.6 0.1 0.51 10.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2135) Fam20C PF06702.12 CDJ39821.1 - 0.25 11.1 0.7 2.3 8.0 0.2 2.1 2 0 0 2 2 2 0 Golgi casein kinase, C-terminal, Fam20 ANAPC_CDC26 PF10471.9 CDJ39821.1 - 2.1 9.3 22.5 0.5 11.2 1.3 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 SUIM_assoc PF16619.5 CDJ39821.1 - 6.9 6.8 39.0 0.27 11.3 6.7 4.2 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DnaJ PF00226.31 CDJ39822.1 - 3e-06 27.3 1.0 6.9e-06 26.1 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF2722 PF10846.8 CDJ39822.1 - 0.00032 19.8 5.5 0.00032 19.8 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DnaJ-X PF14308.6 CDJ39822.1 - 0.00041 19.8 1.5 0.00041 19.8 1.5 2.2 2 0 0 2 2 2 1 X-domain of DnaJ-containing PepSY_TM PF03929.16 CDJ39822.1 - 0.033 13.9 0.8 0.044 13.4 0.8 1.3 1 0 0 1 1 1 0 PepSY-associated TM region Neur_chan_memb PF02932.16 CDJ39822.1 - 0.059 13.4 1.3 0.092 12.8 1.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ39822.1 - 0.06 12.1 1.7 0.058 12.2 1.7 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CDJ39822.1 - 0.15 12.8 8.8 0.29 11.8 8.8 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ39822.1 - 0.37 10.4 20.9 0.11 12.1 18.3 1.4 2 0 0 2 2 2 0 Spt20 family OATP PF03137.20 CDJ39822.1 - 0.37 9.0 0.5 0.47 8.7 0.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4407 PF14362.6 CDJ39822.1 - 0.61 9.4 8.0 1 8.7 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spore_coat_CotO PF14153.6 CDJ39822.1 - 0.95 9.4 13.2 1.7 8.5 13.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF4834 PF16118.5 CDJ39822.1 - 2.9 8.9 7.2 5.7 8.0 7.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CPSF100_C PF13299.6 CDJ39822.1 - 4.2 7.5 8.2 9.1 6.4 7.9 1.8 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pex26 PF07163.12 CDJ39822.1 - 6.1 6.1 8.1 11 5.3 8.1 1.3 1 0 0 1 1 1 0 Pex26 protein Roughex PF06020.11 CDJ39822.1 - 7.1 5.6 12.8 10 5.1 12.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein ABC_tran PF00005.27 CDJ39823.1 - 3.7e-10 40.5 0.0 4.5e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ39823.1 - 9.5e-05 21.9 0.0 9.6e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ39823.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system WAC_Acf1_DNA_bd PF10537.9 CDJ39824.1 - 0.014 15.9 0.2 0.018 15.6 0.2 1.2 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal REV1_C PF16727.5 CDJ39824.1 - 0.086 13.2 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain Tropomyosin_1 PF12718.7 CDJ39825.1 - 0.055 13.6 11.3 0.11 12.7 11.3 1.4 1 0 0 1 1 1 0 Tropomyosin like SLX9 PF15341.6 CDJ39825.1 - 0.29 11.6 5.9 0.61 10.5 5.9 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 SKA1 PF07160.12 CDJ39825.1 - 4.3 7.1 11.3 3 7.6 6.7 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4407 PF14362.6 CDJ39825.1 - 5.3 6.3 7.9 7.7 5.8 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SR-25 PF10500.9 CDJ39826.1 - 0.94 9.0 16.4 0.1 12.2 4.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3967 PF13152.6 CDJ39827.1 - 1.1 9.1 10.3 11 5.9 10.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3967) UPF1_Zn_bind PF09416.10 CDJ39828.1 - 3.5e-27 95.2 0.1 4.4e-27 94.9 0.1 1.1 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) FTCD_C PF04961.12 CDJ39829.1 - 4.4 7.0 14.1 0.48 10.2 2.3 3.3 3 1 0 3 3 3 0 Formiminotransferase-cyclodeaminase INSIG PF07281.12 CDJ39829.1 - 7.1 6.2 13.7 1.2e+02 2.2 0.0 3.5 2 1 0 2 2 2 0 Insulin-induced protein (INSIG) Hat1_N PF10394.9 CDJ39830.1 - 0.0018 18.5 0.0 0.0023 18.2 0.0 1.2 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus RskA PF10099.9 CDJ39831.1 - 0.029 14.7 12.8 0.033 14.5 12.8 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Rpn3_C PF08375.11 CDJ39831.1 - 0.14 12.6 6.9 0.21 12.0 4.4 1.9 1 1 1 2 2 2 0 Proteasome regulatory subunit C-terminal NEMP PF10225.9 CDJ39831.1 - 2.5 7.7 3.9 2.6 7.6 3.9 1.0 1 0 0 1 1 1 0 NEMP family Spt20 PF12090.8 CDJ39831.1 - 4 7.0 32.3 4.2 6.9 32.3 1.2 1 0 0 1 1 1 0 Spt20 family V_ATPase_I PF01496.19 CDJ39831.1 - 8.4 4.2 11.3 8.4 4.2 11.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ39831.1 - 8.6 6.2 38.8 8.8 6.2 38.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Flavodoxin_1 PF00258.25 CDJ39832.1 - 0.00017 21.8 0.1 0.0021 18.3 0.0 2.5 2 1 0 2 2 2 1 Flavodoxin Collagen PF01391.18 CDJ39832.1 - 0.00084 19.0 77.6 0.0097 15.6 26.1 3.7 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Helicase_C PF00271.31 CDJ39833.1 - 6.8e-08 32.8 0.3 4.9e-07 30.1 0.1 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ39833.1 - 1.4e-05 24.9 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_60s PF00428.19 CDJ39833.1 - 1.6 9.4 8.1 0.4 11.3 4.9 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein SUIM_assoc PF16619.5 CDJ39834.1 - 0.024 14.7 0.1 0.024 14.7 0.1 2.9 2 2 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ39834.1 - 0.1 12.9 14.3 0.16 12.2 14.3 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ39834.1 - 0.13 12.2 14.5 0.15 12.0 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ39834.1 - 1.6 8.6 7.8 1.9 8.4 7.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Tim54 PF11711.8 CDJ39834.1 - 3.6 6.3 6.6 5.1 5.8 6.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 CDJ39834.1 - 8.8 5.0 7.0 11 4.6 7.0 1.1 1 0 0 1 1 1 0 Presenilin RNA_lig_T4_1 PF09511.10 CDJ39835.1 - 7 6.4 6.5 20 5.0 6.1 2.0 1 1 0 1 1 1 0 RNA ligase Herpes_pp85 PF04637.12 CDJ39836.1 - 10 4.4 6.7 12 4.2 6.7 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SET PF00856.28 CDJ39837.1 - 3.6e-15 56.8 1.7 2.4e-14 54.1 0.0 2.8 2 2 0 2 2 2 1 SET domain Pre-SET PF05033.16 CDJ39837.1 - 0.002 18.8 2.5 1.2 9.8 1.6 2.7 1 1 1 2 2 2 2 Pre-SET motif Apt1 PF10351.9 CDJ39837.1 - 0.049 12.5 5.6 0.063 12.1 5.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SRP-alpha_N PF04086.13 CDJ39837.1 - 7 6.5 8.0 10 6.0 8.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NST1 PF13945.6 CDJ39840.1 - 0.37 10.9 4.0 0.25 11.4 1.4 1.9 1 1 0 1 1 1 0 Salt tolerance down-regulator TFIIA PF03153.13 CDJ39840.1 - 0.72 9.8 9.7 1.3 9.0 9.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3446 PF11928.8 CDJ39841.1 - 1.7 9.0 32.4 0.47 10.8 9.9 3.5 2 1 1 3 3 3 0 Early growth response N-terminal domain SUIM_assoc PF16619.5 CDJ39842.1 - 2.2 8.4 9.9 2 8.6 9.9 1.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 eRF1_3 PF03465.15 CDJ39843.1 - 4.8e-36 123.7 1.2 6.4e-36 123.3 1.2 1.2 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 CDJ39843.1 - 6.3e-09 36.2 0.1 2.4e-07 31.1 0.0 2.5 2 0 0 2 2 2 1 eRF1 domain 2 Ribosomal_L7Ae PF01248.26 CDJ39843.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NAD_binding_2 PF03446.15 CDJ39845.1 - 1e-13 51.7 0.2 1.1e-13 51.6 0.2 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 CDJ39845.1 - 0.00062 19.7 0.2 0.00074 19.5 0.2 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CDJ39845.1 - 0.035 14.7 0.1 0.039 14.5 0.1 1.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Hamartin PF04388.12 CDJ39846.1 - 1.6 7.3 28.2 2.5 6.7 28.2 1.2 1 0 0 1 1 1 0 Hamartin protein Utp14 PF04615.13 CDJ39846.1 - 4.1 5.8 50.0 0.21 10.1 44.1 1.6 2 0 0 2 2 2 0 Utp14 protein tRNA-synt_2d PF01409.20 CDJ39847.1 - 8.7e-15 54.9 1.0 3.3e-08 33.3 0.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Hist_deacetyl PF00850.19 CDJ39847.1 - 2.6e-08 33.7 4.9 2.6e-08 33.7 4.9 2.8 2 1 1 3 3 3 1 Histone deacetylase domain SUIM_assoc PF16619.5 CDJ39847.1 - 0.019 15.0 2.0 0.019 15.0 2.0 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ39847.1 - 2.1 8.6 0.0 2.1 8.6 0.0 9.1 4 3 2 6 6 6 0 Anti-sigma-K factor rskA RRM_1 PF00076.22 CDJ39848.1 - 0.0069 16.2 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1645 PF07816.11 CDJ39848.1 - 2.7 8.5 10.8 0.41 11.2 1.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) DUF572 PF04502.13 CDJ39849.1 - 9.9 5.7 27.1 0.74 9.4 4.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) Trp_oprn_chp PF09534.10 CDJ39850.1 - 0.0051 16.6 9.9 0.0051 16.6 9.9 3.3 2 1 1 3 3 3 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3446 PF11928.8 CDJ39850.1 - 0.019 15.3 5.8 0.019 15.3 5.8 5.3 4 2 1 5 5 5 0 Early growth response N-terminal domain PGI PF00342.19 CDJ39851.1 - 8.3e-66 222.5 0.0 9.9e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Mqo PF06039.15 CDJ39852.1 - 5.4e-07 28.5 0.0 0.012 14.2 0.0 2.1 1 1 1 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Gly-zipper_OmpA PF13436.6 CDJ39854.1 - 0.0014 18.4 17.3 0.11 12.3 17.3 2.8 1 1 0 1 1 1 1 Glycine-zipper domain Bacteriocin_IIc PF10439.9 CDJ39854.1 - 0.051 13.7 17.6 2.2 8.4 14.1 2.7 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.6 CDJ39854.1 - 0.21 11.3 12.3 1.4 8.8 12.3 2.4 1 1 0 1 1 1 0 YMGG-like Gly-zipper PT PF04886.12 CDJ39854.1 - 2 8.0 16.3 0.06 12.9 7.3 2.8 2 1 0 2 2 2 0 PT repeat Gly-zipper_Omp PF13488.6 CDJ39854.1 - 2.6 8.1 7.4 2.3 8.3 5.8 1.8 1 1 0 1 1 1 0 Glycine zipper DUF4114 PF13448.6 CDJ39855.1 - 0.18 12.6 0.4 0.24 12.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4114) DALR_2 PF09190.11 CDJ39855.1 - 0.21 12.1 0.9 0.29 11.7 0.9 1.6 1 1 0 1 1 1 0 DALR domain LPD1 PF18796.1 CDJ39855.1 - 0.22 11.6 2.1 0.28 11.3 2.1 1.2 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 1 RskA PF10099.9 CDJ39856.1 - 0.00068 20.0 7.6 0.0017 18.7 2.6 2.2 1 1 1 2 2 2 2 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ39857.1 - 0.59 8.8 3.7 0.55 8.9 3.7 1.1 1 0 0 1 1 1 0 Presenilin Med15 PF09606.10 CDJ39857.1 - 3 6.4 32.7 3.9 6.0 32.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Coilin_N PF15862.5 CDJ39857.1 - 9.5 6.0 13.8 13 5.5 13.8 1.2 1 0 0 1 1 1 0 Coilin N-terminus TFIIA PF03153.13 CDJ39858.1 - 0.35 10.8 26.2 0.43 10.5 26.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ39858.1 - 3.4 5.8 15.9 3.6 5.7 15.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DASH_Spc34 PF08657.10 CDJ39859.1 - 0.0047 16.8 1.0 0.0052 16.6 1.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Spc34 N_NLPC_P60 PF12912.7 CDJ39859.1 - 0.0077 16.6 4.0 0.015 15.7 2.7 1.9 2 0 0 2 2 2 1 NLPC_P60 stabilising domain, N term DivIC PF04977.15 CDJ39859.1 - 0.13 12.1 5.9 0.28 11.0 4.0 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 CDJ39859.1 - 0.15 11.4 9.3 0.25 10.7 9.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 CDJ39859.1 - 0.52 10.3 17.0 0.61 10.0 17.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP1 PF08601.10 CDJ39859.1 - 1.6 8.4 15.8 2.1 8.0 15.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 SF1-HH PF16275.5 CDJ39859.1 - 1.8 8.9 4.5 13 6.1 1.6 2.1 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain OmpH PF03938.14 CDJ39859.1 - 2.7 8.3 17.5 5.4 7.4 17.5 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) YlqD PF11068.8 CDJ39859.1 - 8.9 6.7 14.7 2 8.8 9.7 2.0 2 0 0 2 2 2 0 YlqD protein DUF1635 PF07795.11 CDJ39860.1 - 0.0075 16.2 8.8 0.012 15.5 8.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) Macoilin PF09726.9 CDJ39860.1 - 0.11 11.0 8.0 0.13 10.8 8.0 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 CDJ39860.1 - 0.24 11.0 11.0 0.31 10.6 11.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Miga PF10265.9 CDJ39860.1 - 0.96 8.4 9.2 1.1 8.1 9.2 1.1 1 0 0 1 1 1 0 Mitoguardin Presenilin PF01080.17 CDJ39860.1 - 2.3 6.9 7.8 2.5 6.8 7.8 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ39860.1 - 2.5 8.1 5.4 2.8 7.9 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 CDJ39860.1 - 3.9 5.5 7.5 3.6 5.6 7.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RAP1 PF07218.11 CDJ39860.1 - 5.6 5.1 6.9 6 5.0 6.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Dicty_REP PF05086.12 CDJ39860.1 - 8.7 4.2 7.5 9.8 4.0 7.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S64 PF08192.11 CDJ39860.1 - 8.7 4.7 10.6 10 4.5 10.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Utp14 PF04615.13 CDJ39863.1 - 8.5e-06 24.7 95.4 0.00068 18.4 50.1 2.1 1 1 1 2 2 2 2 Utp14 protein SR-25 PF10500.9 CDJ39863.1 - 0.00053 19.7 15.7 0.00053 19.7 15.7 3.7 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein SMAP PF15477.6 CDJ39864.1 - 1.6e-12 48.2 0.0 1.6e-12 48.2 0.0 3.5 1 1 1 2 2 2 1 Small acidic protein family Cwf_Cwc_15 PF04889.12 CDJ39864.1 - 0.0029 17.4 3.7 0.0029 17.4 3.7 2.1 1 1 1 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DUF677 PF05055.12 CDJ39864.1 - 0.011 14.7 0.8 0.013 14.4 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) CHIP_TPR_N PF18391.1 CDJ39864.1 - 0.065 14.0 6.7 0.94 10.3 0.2 3.4 3 0 0 3 3 3 0 CHIP N-terminal tetratricopeptide repeat domain Lentiviral_Tat PF02998.14 CDJ39864.1 - 0.1 12.7 0.2 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Lentiviral Tat protein SR-25 PF10500.9 CDJ39864.1 - 2.2 7.8 33.9 0.17 11.5 26.5 2.5 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ39864.1 - 2.2 8.2 19.9 2.7 7.9 19.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TAF1D PF15333.6 CDJ39864.1 - 2.8 7.6 10.7 0.46 10.2 5.5 2.0 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D DUF4614 PF15391.6 CDJ39864.1 - 5.3 7.0 17.2 0.66 9.9 10.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) K_channel_TID PF07941.11 CDJ39865.1 - 1.4 9.4 11.6 1.5 9.3 11.2 1.4 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain WD40 PF00400.32 CDJ39866.1 - 4.5e-13 49.5 1.6 0.0021 18.8 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-CCCH PF00642.24 CDJ39866.1 - 4.2e-05 23.3 5.8 0.00013 21.7 5.8 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ39866.1 - 0.00081 19.1 6.1 0.0018 18.0 6.1 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDJ39866.1 - 0.0066 16.5 7.6 0.017 15.2 7.6 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 CDJ39866.1 - 0.058 13.9 2.6 0.14 12.7 2.6 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CDJ39866.1 - 0.06 14.1 0.3 0.19 12.4 0.4 1.7 2 0 0 2 2 2 0 Torus domain Evr1_Alr PF04777.13 CDJ39867.1 - 6.4e-18 65.1 0.0 8.8e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family MFS_1 PF07690.16 CDJ39868.1 - 1.5e-08 34.0 12.5 2e-08 33.6 12.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 CDJ39868.1 - 0.0091 14.4 0.5 0.017 13.5 0.3 1.5 1 1 0 1 1 1 1 Transmembrane secretion effector Sugar_tr PF00083.24 CDJ39868.1 - 0.012 14.5 1.7 0.031 13.2 0.6 2.0 2 0 0 2 2 2 0 Sugar (and other) transporter DUF2722 PF10846.8 CDJ39868.1 - 0.013 14.5 0.1 0.015 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ39868.1 - 0.013 15.1 4.6 0.019 14.6 4.6 1.1 1 0 0 1 1 1 0 Spt20 family TMEM208_SND2 PF05620.11 CDJ39868.1 - 0.11 12.3 0.3 0.23 11.2 0.3 1.5 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 SUIM_assoc PF16619.5 CDJ39868.1 - 0.91 9.6 12.5 2.2 8.4 12.5 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SCO1-SenC PF02630.14 CDJ39872.1 - 1.2e-42 145.0 0.0 2.4e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 SCO1/SenC Ndc1_Nup PF09531.10 CDJ39872.1 - 1.4e-05 24.1 6.0 1.4e-05 24.0 6.0 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Atg14 PF10186.9 CDJ39872.1 - 0.00014 21.1 6.3 0.00014 21.1 6.3 1.4 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 BAF1_ABF1 PF04684.13 CDJ39872.1 - 0.0036 16.4 6.0 0.0059 15.7 6.0 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor SWIB PF02201.18 CDJ39872.1 - 0.025 14.5 0.0 0.025 14.5 0.0 2.1 2 0 0 2 2 2 0 SWIB/MDM2 domain Auxin_canalis PF05703.11 CDJ39872.1 - 0.33 10.8 13.0 0.69 9.8 0.1 2.2 2 0 0 2 2 2 0 Auxin canalisation NAD_synthase PF02540.17 CDJ39875.1 - 5.8e-13 48.5 0.0 8.3e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 NAD synthase DUF3446 PF11928.8 CDJ39876.1 - 0.00022 21.5 10.2 0.00032 21.0 10.2 1.3 1 0 0 1 1 1 1 Early growth response N-terminal domain Herpes_ICP4_N PF03584.15 CDJ39876.1 - 0.19 11.5 0.8 0.42 10.4 0.1 1.7 2 0 0 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region CCDC106 PF15794.5 CDJ39876.1 - 0.5 10.0 8.2 0.69 9.6 8.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SR-25 PF10500.9 CDJ39876.1 - 1 8.9 28.3 1.5 8.4 28.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DpaA_N PF16924.5 CDJ39877.1 - 0.08 13.0 0.4 0.69 10.0 0.0 2.1 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain SUIM_assoc PF16619.5 CDJ39878.1 - 0.004 17.2 1.9 0.017 15.1 1.9 2.1 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Roughex PF06020.11 CDJ39879.1 - 0.02 14.0 11.4 0.023 13.8 11.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PBP1_TM PF14812.6 CDJ39879.1 - 0.03 14.7 0.4 0.035 14.5 0.4 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3527 PF12043.8 CDJ39879.1 - 0.11 12.0 8.5 0.13 11.8 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Lin-8 PF03353.15 CDJ39879.1 - 0.51 9.9 15.7 0.58 9.7 15.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spt20 PF12090.8 CDJ39879.1 - 0.55 9.8 22.0 0.58 9.7 22.0 1.2 1 0 0 1 1 1 0 Spt20 family DUF908 PF06012.12 CDJ39879.1 - 0.67 9.3 13.0 0.8 9.1 13.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Tim54 PF11711.8 CDJ39879.1 - 0.79 8.4 7.8 0.86 8.3 7.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1645 PF07816.11 CDJ39879.1 - 1.1 9.8 12.9 1.4 9.5 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) CytochromB561_N PF09786.9 CDJ39879.1 - 1.3 8.0 13.5 1.4 7.8 13.5 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Band_3_cyto PF07565.13 CDJ39879.1 - 1.4 8.7 8.8 1.6 8.5 8.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Zip PF02535.22 CDJ39879.1 - 2 7.6 7.4 2.1 7.5 7.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.13 CDJ39879.1 - 2 8.3 18.5 2.2 8.2 18.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 CDJ39879.1 - 3.1 7.8 14.6 1.8 8.6 12.9 1.4 1 1 1 2 2 2 0 Telomere-associated protein TERB2 CPSF100_C PF13299.6 CDJ39879.1 - 3.1 7.9 7.5 3.3 7.9 7.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Macoilin PF09726.9 CDJ39879.1 - 6.7 5.1 16.3 7.3 5.0 16.3 1.0 1 0 0 1 1 1 0 Macoilin family DUF5521 PF17659.1 CDJ39879.1 - 7.7 4.2 12.0 8.4 4.1 12.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) GREB1 PF15782.5 CDJ39879.1 - 7.8 3.5 17.5 8.6 3.3 17.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MAJIN PF15077.6 CDJ39879.1 - 9.1 6.0 9.1 12 5.6 9.1 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein RskA PF10099.9 CDJ39880.1 - 0.18 12.1 0.0 0.18 12.1 0.0 5.6 1 1 1 3 3 3 0 Anti-sigma-K factor rskA APC1_C PF18122.1 CDJ39880.1 - 0.52 10.2 6.6 0.36 10.8 2.0 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain COPI_assoc PF08507.10 CDJ39881.1 - 0.0045 17.0 4.6 0.0069 16.4 4.6 1.2 1 0 0 1 1 1 1 COPI associated protein Polysacc_synt_3 PF13440.6 CDJ39881.1 - 0.063 12.5 0.3 0.091 12.0 0.3 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Apq12 PF12716.7 CDJ39881.1 - 4.9 7.2 9.1 0.22 11.5 0.6 2.4 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis HATPase_c PF02518.26 CDJ39883.1 - 8.2e-06 26.3 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDJ39883.1 - 2.4e-05 24.2 0.0 4.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_60s PF00428.19 CDJ39883.1 - 0.032 14.8 6.9 0.15 12.7 6.9 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein SoxY PF13501.6 CDJ39883.1 - 0.13 12.4 1.4 0.33 11.2 0.4 2.0 2 0 0 2 2 2 0 Sulfur oxidation protein SoxY CDC45 PF02724.14 CDJ39885.1 - 0.00056 18.4 6.3 0.00056 18.4 6.3 1.9 2 0 0 2 2 2 1 CDC45-like protein RskA PF10099.9 CDJ39885.1 - 0.0012 19.2 12.8 0.0012 19.2 12.8 3.7 2 2 1 3 3 3 1 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ39885.1 - 0.03 14.9 0.7 0.03 14.9 0.7 3.9 4 1 0 4 4 3 0 60s Acidic ribosomal protein EOS1 PF12326.8 CDJ39885.1 - 0.064 13.2 5.4 0.23 11.4 3.0 2.3 2 0 0 2 2 2 0 N-glycosylation protein DUF4746 PF15928.5 CDJ39885.1 - 0.13 11.7 13.2 0.12 11.8 8.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF2052 PF09747.9 CDJ39885.1 - 0.15 12.2 20.3 0.19 11.8 12.6 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Lin-8 PF03353.15 CDJ39885.1 - 0.26 10.8 22.9 0.052 13.1 15.8 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF3405 PF11885.8 CDJ39885.1 - 0.39 9.3 8.8 0.66 8.5 8.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Bul1_N PF04425.12 CDJ39885.1 - 0.66 8.7 9.4 1.1 7.9 9.4 1.4 1 0 0 1 1 1 0 Bul1 N terminus GPCR_chapero_1 PF11904.8 CDJ39885.1 - 0.67 9.3 7.9 0.08 12.4 3.6 1.7 2 0 0 2 2 2 0 GPCR-chaperone PAT1 PF09770.9 CDJ39885.1 - 0.8 7.9 34.5 0.062 11.6 27.6 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Zip PF02535.22 CDJ39885.1 - 0.84 8.8 5.1 1.6 7.8 5.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 CDJ39885.1 - 1.2 7.5 5.7 0.55 8.6 2.8 1.7 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Membralin PF09746.9 CDJ39885.1 - 1.3 8.0 6.1 2.2 7.2 6.1 1.4 1 0 0 1 1 1 0 Tumour-associated protein eIF-3_zeta PF05091.12 CDJ39885.1 - 1.4 7.8 23.4 0.0082 15.2 14.7 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Connexin PF00029.19 CDJ39885.1 - 3 7.5 15.4 13 5.5 13.5 2.2 2 0 0 2 2 2 0 Connexin GREB1 PF15782.5 CDJ39885.1 - 6 3.8 18.3 0.063 10.4 10.9 1.5 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 CDJ39885.1 - 7 5.6 19.2 0.37 9.8 13.0 1.8 2 0 0 2 2 2 0 Solute carrier family 12 CLN3 PF02487.17 CDJ39885.1 - 7.1 5.6 13.1 0.7 8.9 8.3 1.7 2 0 0 2 2 2 0 CLN3 protein SRP-alpha_N PF04086.13 CDJ39885.1 - 7.5 6.4 28.8 1.2 9.0 0.1 2.6 3 0 0 3 3 3 0 Signal recognition particle, alpha subunit, N-terminal Peptidase_S64 PF08192.11 CDJ39885.1 - 9.4 4.6 14.2 1.2 7.6 10.0 1.5 2 0 0 2 2 2 0 Peptidase family S64 ALMT PF11744.8 CDJ39885.1 - 9.7 4.9 12.3 2.4 6.9 9.0 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter MMR1 PF08505.10 CDJ39885.1 - 10 6.4 25.6 0.68 10.2 17.4 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Myosin_head PF00063.21 CDJ39887.1 - 3.8e-123 412.1 0.8 1e-90 304.9 0.6 3.3 3 0 0 3 3 3 3 Myosin head (motor domain) AAA_22 PF13401.6 CDJ39887.1 - 0.0089 16.3 0.5 0.037 14.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CDJ39887.1 - 0.078 12.2 0.0 0.24 10.7 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin Ribosomal_L14 PF00238.19 CDJ39889.1 - 3.9e-33 114.1 0.0 4.7e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PARG_cat PF05028.14 CDJ39890.1 - 3.1e-36 125.4 0.0 1.4e-18 67.3 0.0 3.6 4 0 0 4 4 4 3 Poly (ADP-ribose) glycohydrolase (PARG) URO-D PF01208.17 CDJ39891.1 - 1.9e-94 316.7 0.0 3e-94 316.0 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Pro_isomerase PF00160.21 CDJ39894.1 - 1.5e-48 165.1 0.0 1.7e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Methyltransf_16 PF10294.9 CDJ39895.1 - 2.6e-05 24.0 0.5 0.077 12.7 0.0 2.7 2 2 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 CDJ39895.1 - 0.00044 19.7 0.0 0.00068 19.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CDJ39895.1 - 0.081 12.5 0.3 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Macoilin PF09726.9 CDJ39896.1 - 1.1 7.7 8.0 1.5 7.3 8.0 1.1 1 0 0 1 1 1 0 Macoilin family Beach PF02138.18 CDJ39897.1 - 3.3e-73 246.4 0.0 6e-42 143.9 0.0 2.5 2 0 0 2 2 2 2 Beige/BEACH domain WD40 PF00400.32 CDJ39897.1 - 0.0041 17.9 0.1 0.047 14.6 0.0 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat TFIIA PF03153.13 CDJ39897.1 - 7.9 6.4 51.3 0.062 13.3 11.5 4.6 4 1 0 4 4 4 0 Transcription factor IIA, alpha/beta subunit Surface_antigen PF11054.8 CDJ39898.1 - 2.4e-22 79.8 4.6 3.6e-20 72.7 3.4 2.9 2 1 0 2 2 2 2 Sporozoite TA4 surface antigen GRP PF07172.11 CDJ39898.1 - 0.17 12.6 27.2 28 5.5 25.9 3.0 3 0 0 3 3 3 0 Glycine rich protein family Surface_antigen PF11054.8 CDJ39899.1 - 1.2e-23 84.0 0.2 1.6e-23 83.7 0.2 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen FBPase PF00316.20 CDJ39900.1 - 5.8e-67 224.8 0.1 7.7e-67 224.4 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NucS PF01939.16 CDJ39900.1 - 0.099 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Endonuclease NucS NdhM PF10664.9 CDJ39900.1 - 0.15 12.3 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Proteasome PF00227.26 CDJ39901.1 - 3.2e-21 75.7 0.0 3.8e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF637 PF04830.13 CDJ39901.1 - 0.017 14.9 0.2 0.024 14.5 0.2 1.3 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) Pkinase PF00069.25 CDJ39902.1 - 0.038 13.4 0.0 0.083 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain Not3 PF04065.15 CDJ39903.1 - 1.6e-56 191.3 14.3 1.6e-56 191.3 14.3 1.7 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CDJ39903.1 - 1.5e-33 115.7 0.1 4e-33 114.3 0.1 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Ribosomal_60s PF00428.19 CDJ39904.1 - 0.3 11.7 4.4 0.71 10.5 4.4 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.25 CDJ39905.1 - 2.2e-70 237.0 0.0 3.5e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ39905.1 - 3.6e-29 101.9 0.0 5.6e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ39905.1 - 0.0017 17.2 0.0 0.0074 15.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CDJ39905.1 - 0.0045 16.9 0.3 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ39905.1 - 0.018 14.4 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.29 CDJ39905.1 - 0.13 12.8 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 PH domain Thioredoxin_8 PF13905.6 CDJ39906.1 - 3e-33 114.0 0.0 9.5e-27 93.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin PF00085.20 CDJ39906.1 - 1.7e-08 34.4 0.0 3.1e-07 30.3 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin Redoxin PF08534.10 CDJ39906.1 - 1.7e-08 34.3 0.0 3.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 CDJ39906.1 - 1e-07 32.4 0.0 2.4e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CDJ39906.1 - 4.1e-07 30.0 0.0 1.2e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family SCO1-SenC PF02630.14 CDJ39906.1 - 4.7e-05 23.3 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_7 PF13899.6 CDJ39906.1 - 0.049 13.8 0.0 0.34 11.1 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin-like DUF1180 PF06679.12 CDJ39907.1 - 0.019 15.4 3.3 0.042 14.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) XRN_M PF17846.1 CDJ39909.1 - 0.024 13.6 0.3 0.091 11.7 0.2 1.8 2 0 0 2 2 2 0 Xrn1 helical domain AAA_6 PF12774.7 CDJ39910.1 - 1.4e-131 438.3 0.0 6.6e-131 436.1 0.0 2.3 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ39910.1 - 5.2e-113 378.2 8.2 5.2e-113 378.2 8.2 3.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CDJ39910.1 - 3.3e-110 369.4 1.2 3.3e-110 369.4 1.2 4.7 4 1 1 5 5 5 2 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 CDJ39910.1 - 1.7e-67 226.8 0.1 1.7e-67 226.8 0.1 3.8 5 0 0 5 5 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 CDJ39910.1 - 5.8e-63 212.6 0.0 7.1e-62 209.1 0.0 3.0 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CDJ39910.1 - 3.2e-47 161.3 0.1 1.1e-46 159.5 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CDJ39910.1 - 2.4e-34 118.4 0.0 7.2e-28 97.3 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 CDJ39910.1 - 2.6e-33 115.5 11.5 4.4e-33 114.8 11.5 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CDJ39910.1 - 1e-32 113.2 0.0 2.6e-32 111.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ39910.1 - 1.8e-30 105.5 0.4 1.2e-29 102.8 0.0 2.9 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CDJ39910.1 - 4.2e-30 104.5 0.0 2.1e-11 44.0 0.0 7.0 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDJ39910.1 - 8.3e-23 80.9 0.1 3.1e-22 79.0 0.1 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CDJ39910.1 - 2.1e-15 57.3 0.1 0.0013 19.1 0.0 5.6 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ39910.1 - 2.3e-12 47.4 1.9 0.0025 18.1 0.0 7.4 6 1 1 7 7 6 1 AAA domain AAA_16 PF13191.6 CDJ39910.1 - 3.2e-07 30.9 6.4 6.9 7.0 0.1 7.3 5 1 1 6 6 5 0 AAA ATPase domain AAA_18 PF13238.6 CDJ39910.1 - 3.5e-07 30.8 0.0 16 6.0 0.0 5.3 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 CDJ39910.1 - 1.7e-05 24.1 0.0 0.13 11.3 0.0 3.4 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_30 PF13604.6 CDJ39910.1 - 5.1e-05 23.1 1.5 5.7 6.6 0.0 5.3 5 0 0 5 5 5 0 AAA domain AAA_33 PF13671.6 CDJ39910.1 - 5.3e-05 23.4 3.9 0.46 10.6 0.0 5.0 5 0 0 5 5 4 1 AAA domain TelA PF05816.11 CDJ39910.1 - 0.00047 19.3 4.5 0.00047 19.3 4.5 3.5 2 0 0 2 2 1 1 Toxic anion resistance protein (TelA) AAA_25 PF13481.6 CDJ39910.1 - 0.00051 19.7 1.7 0.024 14.2 0.0 3.7 4 0 0 4 4 3 1 AAA domain IstB_IS21 PF01695.17 CDJ39910.1 - 0.00062 19.6 0.2 0.77 9.5 0.0 4.9 5 0 0 5 5 4 1 IstB-like ATP binding protein AAA_19 PF13245.6 CDJ39910.1 - 0.0012 19.2 1.2 0.53 10.6 0.0 5.3 6 0 0 6 6 5 1 AAA domain Asn_synthase PF00733.21 CDJ39910.1 - 0.0051 16.5 0.2 0.011 15.4 0.2 1.6 1 0 0 1 1 1 1 Asparagine synthase Rad17 PF03215.15 CDJ39910.1 - 0.0073 16.3 0.3 20 5.1 0.0 4.6 6 0 0 6 6 4 0 Rad17 P-loop domain TsaE PF02367.17 CDJ39910.1 - 0.008 16.2 1.5 11 6.0 0.0 4.2 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_1 PF17857.1 CDJ39910.1 - 0.0096 16.1 0.0 0.028 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RNA_helicase PF00910.22 CDJ39910.1 - 0.018 15.4 0.1 1.2e+02 3.1 0.0 4.9 4 0 0 4 4 4 0 RNA helicase RuvB_N PF05496.12 CDJ39910.1 - 0.025 14.3 0.1 1.8 8.3 0.0 3.2 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain MPS2 PF17060.5 CDJ39910.1 - 0.028 13.7 11.4 0.36 10.0 2.8 2.6 2 0 0 2 2 2 0 Monopolar spindle protein 2 Mg_chelatase PF01078.21 CDJ39910.1 - 0.035 13.5 6.5 6 6.2 0.0 4.6 4 1 1 5 5 5 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 CDJ39910.1 - 0.049 13.2 0.2 0.43 10.1 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NBD94 PF16830.5 CDJ39910.1 - 0.12 12.8 6.1 0.11 12.9 2.4 2.9 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH LPP PF04728.13 CDJ39910.1 - 0.48 10.8 4.9 22 5.5 0.8 4.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ABC_tran PF00005.27 CDJ39910.1 - 0.59 10.7 9.9 17 5.9 0.0 5.8 7 0 0 7 7 4 0 ABC transporter Atg14 PF10186.9 CDJ39910.1 - 1.1 8.3 19.7 2.3 7.2 4.0 2.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 CDJ39910.1 - 1.8 7.4 23.5 0.67 8.8 7.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF812) ATG16 PF08614.11 CDJ39910.1 - 2.7 8.2 26.1 3.2 7.9 9.3 3.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) AAA_24 PF13479.6 CDJ39910.1 - 2.9 7.6 7.2 19 4.9 0.0 4.2 5 0 0 5 5 3 0 AAA domain Sec5 PF15469.6 CDJ39910.1 - 4.4 7.1 7.7 18 5.1 2.0 3.5 2 1 0 2 2 2 0 Exocyst complex component Sec5 DUF4407 PF14362.6 CDJ39910.1 - 6.2 6.1 22.5 7.2 5.9 3.9 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ERM PF00769.19 CDJ39910.1 - 7.2 6.3 42.4 5.1 6.8 14.1 3.5 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Ribosomal_L29 PF00831.23 CDJ39911.1 - 7.6e-19 67.4 2.0 7.6e-19 67.4 2.0 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein TLD PF07534.16 CDJ39912.1 - 3.5e-20 72.6 0.0 4.2e-19 69.1 0.0 2.0 2 0 0 2 2 2 1 TLD Cation_ATPase_N PF00690.26 CDJ39913.1 - 0.06 13.0 0.1 0.41 10.4 0.0 2.1 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus SUI1 PF01253.22 CDJ39914.1 - 9.5e-16 58.1 1.8 7.5e-15 55.2 0.1 2.2 2 0 0 2 2 2 1 Translation initiation factor SUI1 PRIMA1 PF16101.5 CDJ39917.1 - 0.00032 20.7 0.0 0.0008 19.4 0.0 1.7 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 DUF3357 PF11837.8 CDJ39917.1 - 0.025 15.0 3.1 1.3 9.5 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) DUF202 PF02656.15 CDJ39918.1 - 0.0055 17.1 4.0 0.095 13.2 1.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF202) Holin_SPP1 PF04688.13 CDJ39918.1 - 0.18 12.0 0.2 0.43 10.8 0.2 1.5 1 0 0 1 1 1 0 SPP1 phage holin DUF2518 PF10726.9 CDJ39918.1 - 0.2 11.3 0.7 0.42 10.3 0.7 1.6 1 0 0 1 1 1 0 Protein of function (DUF2518) MgtE PF01769.16 CDJ39918.1 - 1.5 9.2 9.6 13 6.1 8.6 2.3 2 1 0 2 2 2 0 Divalent cation transporter FrhB_FdhB_C PF04432.13 CDJ39920.1 - 0.0067 16.3 0.1 0.52 10.1 0.1 2.1 2 0 0 2 2 2 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus HNOBA PF07701.14 CDJ39920.1 - 0.13 11.7 1.5 0.71 9.3 0.0 2.2 2 0 0 2 2 2 0 Heme NO binding associated TFIIA PF03153.13 CDJ39920.1 - 0.17 11.8 16.2 0.21 11.6 16.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ39920.1 - 0.2 11.8 15.4 0.48 10.5 5.6 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ39920.1 - 3.2 7.3 18.2 0.72 9.4 12.1 2.1 2 0 0 2 2 2 0 Spt20 family EFG_IV PF03764.18 CDJ39921.1 - 2.5e-29 101.5 0.0 4e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CDJ39921.1 - 1.1e-14 54.2 0.0 9.1e-13 48.1 0.0 2.2 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU PF00009.27 CDJ39921.1 - 8.9e-09 35.2 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CDJ39921.1 - 0.001 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 CDJ39921.1 - 0.052 13.4 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Fe_hyd_lg_C PF02906.14 CDJ39922.1 - 2.7e-14 53.4 4.2 6.1e-08 32.6 0.0 2.9 2 1 1 3 3 3 2 Iron only hydrogenase large subunit, C-terminal domain Adaptin_binding PF10199.9 CDJ39922.1 - 0.0014 19.2 0.0 0.0067 17.0 0.0 2.2 1 1 1 2 2 2 1 Alpha and gamma adaptin binding protein p34 PepSY_TM_like_2 PF16357.5 CDJ39922.1 - 0.023 14.7 4.1 0.049 13.6 4.1 1.5 1 0 0 1 1 1 0 Putative PepSY_TM-like PDEase_II PF02112.15 CDJ39922.1 - 0.064 12.4 0.9 0.096 11.8 0.9 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II DUF3810 PF12725.7 CDJ39922.1 - 0.066 12.5 2.0 0.11 11.8 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) CLN3 PF02487.17 CDJ39922.1 - 0.19 10.8 2.1 0.38 9.8 2.1 1.4 1 0 0 1 1 1 0 CLN3 protein Prominin PF05478.11 CDJ39922.1 - 0.2 9.6 7.3 0.32 8.9 7.3 1.2 1 0 0 1 1 1 0 Prominin Fer4_22 PF17179.4 CDJ39922.1 - 0.37 11.7 5.6 0.95 10.3 5.6 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain DASH_Spc34 PF08657.10 CDJ39922.1 - 0.48 10.2 7.8 0.88 9.3 7.8 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 Cluap1 PF10234.9 CDJ39922.1 - 0.63 9.4 15.3 1.5 8.2 15.3 1.6 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF1631 PF07793.11 CDJ39922.1 - 0.64 8.4 54.5 0.027 12.9 37.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) PBP_dimer PF03717.15 CDJ39922.1 - 0.9 9.9 8.0 1.5 9.1 8.0 1.2 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain FliP PF00813.20 CDJ39922.1 - 1.5 8.7 6.0 2.7 7.9 6.0 1.3 1 0 0 1 1 1 0 FliP family Folliculin PF11704.8 CDJ39922.1 - 2.5 8.0 11.8 0.083 12.8 4.2 2.2 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Pro_CA PF00484.19 CDJ39922.1 - 2.5 8.4 10.8 0.12 12.6 4.6 1.9 2 0 0 2 2 1 0 Carbonic anhydrase DUF5352 PF17303.2 CDJ39922.1 - 2.9 7.7 7.6 1.7 8.5 5.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5352) DUF2072 PF09845.9 CDJ39922.1 - 3.1 8.1 6.5 8.5 6.6 6.5 1.7 1 0 0 1 1 1 0 Zn-ribbon containing protein EIF4E-T PF10477.9 CDJ39922.1 - 3.7 6.3 14.9 5.6 5.7 14.9 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RLL PF10036.9 CDJ39922.1 - 5.2 6.8 16.5 0.39 10.5 6.8 2.3 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein DUF3533 PF12051.8 CDJ39922.1 - 6.6 5.6 11.9 11 4.8 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) SEP PF08059.13 CDJ39923.1 - 8.3e-21 74.4 0.2 1.5e-20 73.6 0.2 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 CDJ39923.1 - 2.4e-13 50.1 0.0 3.6e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 UBX domain Androgen_recep PF02166.16 CDJ39923.1 - 0.0035 16.3 9.0 0.13 11.1 0.0 2.2 2 0 0 2 2 2 2 Androgen receptor Pribosyltran PF00156.27 CDJ39924.1 - 3.8e-19 68.8 0.0 4.6e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 CDJ39924.1 - 0.07 12.6 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Nucleoside_tran PF01733.18 CDJ39925.1 - 1e-17 64.5 5.2 1e-17 64.5 5.2 2.2 2 0 0 2 2 2 2 Nucleoside transporter NRN1 PF15056.6 CDJ39926.1 - 0.09 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Neuritin protein family Endostatin PF06482.11 CDJ39927.1 - 0.46 9.9 8.8 0.022 14.2 2.4 1.9 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin GAT PF03127.14 CDJ39929.1 - 0.06 13.7 0.2 0.14 12.4 0.1 1.6 2 0 0 2 2 2 0 GAT domain PARP PF00644.20 CDJ39930.1 - 1.1e-53 181.8 0.0 2.6e-53 180.5 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CDJ39930.1 - 7.9e-34 116.7 1.5 2e-33 115.4 1.5 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 CDJ39930.1 - 2.2e-10 40.4 1.8 3.8e-10 39.7 1.0 1.9 2 0 0 2 2 2 1 WGR domain BRCT PF00533.26 CDJ39930.1 - 3.2e-05 24.2 0.0 0.00012 22.4 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-PARP PF00645.18 CDJ39930.1 - 0.00019 22.2 0.1 0.00056 20.7 0.1 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Ribosomal_L27e PF01777.18 CDJ39931.1 - 1.2e-23 83.3 4.9 1.5e-23 82.9 4.9 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CDJ39931.1 - 0.0005 19.9 2.5 0.00093 19.1 2.5 1.4 1 0 0 1 1 1 1 KOW motif rRNA_proc-arch PF13234.6 CDJ39931.1 - 0.037 14.0 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 rRNA-processing arch domain Uds1 PF15456.6 CDJ39932.1 - 0.26 11.5 4.1 11 6.2 0.1 2.7 3 0 0 3 3 3 0 Up-regulated During Septation TssN PF17555.2 CDJ39934.1 - 0.42 9.9 5.2 0.52 9.7 5.2 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Prolamin_like PF05617.11 CDJ39935.1 - 0.005 17.0 0.6 0.44 10.7 0.4 2.2 2 0 0 2 2 2 2 Prolamin-like Pap_E4 PF02711.14 CDJ39935.1 - 0.036 15.0 5.3 0.064 14.2 5.3 1.4 1 0 0 1 1 1 0 E4 protein VIT1 PF01988.19 CDJ39936.1 - 1.3 8.9 9.2 0.034 14.0 0.6 2.6 2 1 0 2 2 2 0 VIT family DUF3584 PF12128.8 CDJ39937.1 - 0.0018 15.9 17.6 0.0018 15.9 17.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) Glyoxalase PF00903.25 CDJ39937.1 - 0.0039 17.4 0.0 1.9 8.7 0.0 3.4 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Protocadherin PF08374.11 CDJ39937.1 - 1 9.3 5.4 1.8 8.5 2.6 2.2 2 0 0 2 2 2 0 Protocadherin ALMT PF11744.8 CDJ39937.1 - 7.1 5.3 10.7 15 4.3 10.7 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter CorA PF01544.18 CDJ39937.1 - 8.4 5.6 10.9 15 4.8 10.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IF3_C PF00707.22 CDJ39938.1 - 1.7e-16 60.0 0.0 8e-16 57.8 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain P53_tetramer PF07710.11 CDJ39938.1 - 0.065 12.6 0.1 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 P53 tetramerisation motif Bac_luciferase PF00296.20 CDJ39938.1 - 0.086 12.2 1.7 0.14 11.6 1.7 1.3 1 1 0 1 1 1 0 Luciferase-like monooxygenase DCP1 PF06058.13 CDJ39939.1 - 2.1e-16 59.9 0.8 1.9e-08 34.2 0.0 2.9 3 0 0 3 3 3 2 Dcp1-like decapping family Pkinase PF00069.25 CDJ39940.1 - 3.2e-71 239.8 0.4 5.3e-71 239.1 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ39940.1 - 8.7e-37 126.8 0.0 1.3e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ39940.1 - 9.1e-28 93.7 9.1 1.1e-06 27.8 0.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CDJ39940.1 - 4e-24 83.0 8.1 3.5e-07 29.4 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDJ39940.1 - 4.2e-23 79.3 4.2 3.2e-05 23.5 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CDJ39940.1 - 2.3e-21 76.0 4.3 9.8e-10 38.7 0.7 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ39940.1 - 4.8e-10 39.1 9.2 0.0011 18.8 0.2 4.5 3 1 1 4 4 4 3 EF-hand domain pair Pkinase_fungal PF17667.1 CDJ39940.1 - 6.6e-07 28.4 0.0 1.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ39940.1 - 7.5e-06 25.4 0.1 1.5e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.7 CDJ39940.1 - 8.9e-06 25.6 4.3 0.007 16.3 0.1 3.6 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ39940.1 - 1.7e-05 25.1 0.3 0.33 11.3 0.3 3.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 CDJ39940.1 - 0.00082 18.8 0.3 0.0034 16.7 0.3 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ39940.1 - 0.0063 16.5 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_10 PF14788.6 CDJ39940.1 - 0.038 13.9 0.2 0.58 10.1 0.0 2.8 2 0 0 2 2 2 0 EF hand COX7B PF05392.11 CDJ39941.1 - 0.14 11.9 0.3 1.3 8.8 0.3 2.8 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB ZZ PF00569.17 CDJ39943.1 - 3.4e-08 33.2 0.7 8.8e-08 31.8 0.7 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-C3HC4_3 PF13920.6 CDJ39943.1 - 1.1e-07 31.6 10.5 1.1e-07 31.6 10.5 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ39943.1 - 4.5e-05 23.5 16.8 4.5e-05 23.5 16.8 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CDJ39943.1 - 0.00023 20.9 14.9 0.00023 20.9 14.9 2.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ39943.1 - 0.00059 19.7 13.7 0.00059 19.7 13.7 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RskA PF10099.9 CDJ39943.1 - 0.00063 20.1 2.9 0.00063 20.1 2.9 6.6 3 3 2 5 5 2 1 Anti-sigma-K factor rskA zf-RING_UBOX PF13445.6 CDJ39943.1 - 0.0037 17.3 8.5 0.0037 17.3 8.5 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDJ39943.1 - 0.0049 17.2 14.7 0.0049 17.2 14.7 2.3 2 0 0 2 2 1 1 Ring finger domain Prok-RING_4 PF14447.6 CDJ39943.1 - 0.017 15.0 11.9 0.017 15.0 11.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Spt20 PF12090.8 CDJ39943.1 - 0.16 11.6 18.0 0.32 10.6 18.0 1.4 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ39943.1 - 1 8.2 13.2 1.5 7.7 13.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ39943.1 - 5.5 6.9 6.3 11 5.9 6.3 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-RING_10 PF16685.5 CDJ39943.1 - 8.2 6.7 19.1 0.028 14.5 9.7 1.8 2 0 0 2 2 1 0 zinc RING finger of MSL2 Pkinase PF00069.25 CDJ39944.1 - 7e-64 215.7 0.0 1.9e-63 214.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ39944.1 - 2.2e-29 102.5 0.0 1.2e-28 100.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ39944.1 - 0.05 12.9 0.0 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Kinase-like NAD_binding_1 PF00175.21 CDJ39945.1 - 6.6e-15 55.7 0.0 1e-14 55.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CDJ39945.1 - 0.23 11.8 0.0 0.44 10.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain UPF0181 PF03701.14 CDJ39946.1 - 0.051 13.2 0.6 1.3 8.7 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0181) DUF3742 PF12553.8 CDJ39946.1 - 0.14 12.3 1.5 0.31 11.2 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) DUF45 PF01863.17 CDJ39948.1 - 1.2 9.2 11.1 3.5 7.6 11.1 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF45 Corona_nucleoca PF00937.18 CDJ39949.1 - 0.88 8.5 9.0 1.4 7.9 9.0 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein MutS_III PF05192.18 CDJ39950.1 - 7.2e-20 72.0 3.6 1.1e-19 71.4 1.5 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CDJ39950.1 - 7.9e-11 42.2 0.0 1.6e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 CDJ39950.1 - 0.0023 18.2 0.1 0.0023 18.2 0.1 4.0 3 1 0 3 3 3 1 MutS domain II SUIM_assoc PF16619.5 CDJ39950.1 - 0.021 14.9 0.7 0.021 14.9 0.7 6.9 4 2 1 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ39950.1 - 0.041 12.8 29.7 0.028 13.4 7.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ39950.1 - 0.46 10.0 56.1 0.2 11.2 16.2 4.3 4 0 0 4 4 4 0 Spt20 family Med15 PF09606.10 CDJ39950.1 - 6.7 5.3 64.0 0.19 10.4 35.7 3.3 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ39952.1 - 0.015 15.4 29.2 0.023 14.7 29.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAF1 PF04857.20 CDJ39952.1 - 0.04 13.1 8.6 0.051 12.7 8.6 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease RskA PF10099.9 CDJ39952.1 - 0.086 13.1 0.0 0.086 13.1 0.0 2.9 1 1 2 3 3 1 0 Anti-sigma-K factor rskA FCP1_C PF09309.10 CDJ39952.1 - 0.31 10.9 14.0 0.48 10.3 14.0 1.2 1 0 0 1 1 1 0 FCP1, C-terminal Baculo_PP31 PF05311.11 CDJ39952.1 - 0.5 9.8 6.1 0.67 9.4 6.1 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Draxin PF15550.6 CDJ39952.1 - 0.53 10.1 8.0 0.69 9.7 8.0 1.1 1 0 0 1 1 1 0 Draxin Presenilin PF01080.17 CDJ39952.1 - 0.77 8.4 13.1 0.96 8.1 13.1 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ39952.1 - 0.99 8.4 9.9 1.2 8.1 9.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF572 PF04502.13 CDJ39952.1 - 1 8.9 12.9 1.5 8.3 12.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.7 CDJ39952.1 - 1.3 7.1 10.6 1.4 6.9 10.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.8 CDJ39952.1 - 1.5 7.6 6.9 1.7 7.3 6.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter FUSC PF04632.12 CDJ39952.1 - 2.5 6.5 20.4 3 6.3 20.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Asp-B-Hydro_N PF05279.11 CDJ39952.1 - 2.6 8.0 13.5 3.4 7.7 13.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Peptidase_S46 PF10459.9 CDJ39952.1 - 3.5 6.2 15.8 4.1 5.9 15.8 1.1 1 0 0 1 1 1 0 Peptidase S46 SUIM_assoc PF16619.5 CDJ39952.1 - 3.7 7.7 40.9 3.9 7.6 17.9 3.6 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CLN3 PF02487.17 CDJ39952.1 - 3.9 6.4 6.3 5.2 6.0 6.3 1.2 1 0 0 1 1 1 0 CLN3 protein PA26 PF04636.13 CDJ39952.1 - 4.2 6.2 9.5 5.2 5.9 9.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Neur_chan_memb PF02932.16 CDJ39952.1 - 8 6.4 10.6 11 6.0 10.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM222A PF15258.6 CDJ39952.1 - 9.8 5.2 22.9 12 4.8 22.9 1.1 1 0 0 1 1 1 0 Protein family of FAM222A UBA_4 PF14555.6 CDJ39953.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain DUF2753 PF10952.8 CDJ39953.1 - 0.024 14.7 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) TcpF PF06340.11 CDJ39954.1 - 0.24 10.2 0.0 0.36 9.6 0.0 1.1 1 0 0 1 1 1 0 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F TFIIA PF03153.13 CDJ39956.1 - 0.42 10.6 14.8 0.42 10.5 14.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dehydrin PF00257.19 CDJ39956.1 - 1.9 9.0 4.4 2.4 8.7 4.4 1.4 1 1 0 1 1 1 0 Dehydrin DUF3552 PF12072.8 CDJ39957.1 - 1.4 8.3 17.1 1.4 8.3 17.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Atg14 PF10186.9 CDJ39957.1 - 2 7.5 15.6 2 7.4 15.6 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MctB PF11382.8 CDJ39957.1 - 3.4 7.3 15.4 3.5 7.3 15.4 1.0 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Spc24 PF08286.11 CDJ39957.1 - 5.6 7.3 13.3 5.7 7.2 13.3 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4140 PF13600.6 CDJ39957.1 - 6.5 7.3 12.1 6.9 7.2 12.1 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) GPHR_N PF12537.8 CDJ39957.1 - 9.9 6.3 5.6 11 6.2 5.6 1.2 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal RRM_1 PF00076.22 CDJ39961.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TetR_C_24 PF17932.1 CDJ39962.1 - 0.15 12.3 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RskA PF10099.9 CDJ39963.1 - 0.14 12.5 13.5 0.18 12.1 13.5 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Myc_N PF01056.18 CDJ39964.1 - 0.26 11.1 2.6 0.31 10.9 2.6 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Dehydrin PF00257.19 CDJ39964.1 - 0.28 11.7 3.4 7.2 7.1 0.2 2.2 2 0 0 2 2 2 0 Dehydrin DUF4131 PF13567.6 CDJ39964.1 - 3.3 7.3 12.0 16 5.1 12.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Tim54 PF11711.8 CDJ39965.1 - 0.13 11.1 5.8 0.088 11.6 4.5 1.3 1 1 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RSRP PF17069.5 CDJ39966.1 - 0.00071 19.2 6.5 0.0013 18.3 6.5 1.5 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 Ephrin_rec_like PF07699.13 CDJ39966.1 - 0.0009 19.0 43.3 0.0013 18.4 9.4 6.2 3 3 3 6 6 6 2 Putative ephrin-receptor like Spt20 PF12090.8 CDJ39966.1 - 0.004 16.8 12.5 0.004 16.8 12.5 3.1 2 1 0 2 2 2 1 Spt20 family Apt1 PF10351.9 CDJ39966.1 - 0.42 9.4 8.7 0.037 12.9 3.4 1.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain Lin-8 PF03353.15 CDJ39966.1 - 0.56 9.7 25.3 0.032 13.8 7.2 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ39966.1 - 1.5 7.3 15.2 0.86 8.1 6.2 2.2 2 0 0 2 2 2 0 Macoilin family DUF2052 PF09747.9 CDJ39966.1 - 7.4 6.6 15.8 3 7.9 8.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) BORG_CEP PF14957.6 CDJ39966.1 - 8.2 7.6 20.7 4.9 8.3 7.8 2.5 2 0 0 2 2 2 0 Cdc42 effector NifU PF01106.17 CDJ39967.1 - 0.00046 20.3 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 NifU-like domain BRF1 PF07741.13 CDJ39967.1 - 0.016 15.5 1.8 0.024 15.0 1.8 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF2722 PF10846.8 CDJ39967.1 - 0.085 11.8 11.0 0.099 11.6 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ39967.1 - 0.12 12.3 18.5 0.12 12.3 18.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ39967.1 - 0.2 10.4 4.0 0.17 10.6 4.0 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CDJ39967.1 - 0.64 10.7 12.6 0.82 10.3 12.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.16 CDJ39967.1 - 2.1 8.3 3.9 2.2 8.3 3.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cytochrom_B558a PF05038.13 CDJ39967.1 - 4 7.0 4.8 7.2 6.1 4.8 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Roughex PF06020.11 CDJ39967.1 - 4.8 6.2 8.2 5.4 6.0 8.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF928 PF06051.12 CDJ39968.1 - 0.042 13.7 2.1 0.044 13.6 1.4 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF928) CCDC53 PF10152.9 CDJ39968.1 - 0.047 14.1 3.5 0.055 13.9 3.5 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Gemini_AL1_M PF08283.11 CDJ39968.1 - 0.11 12.6 0.2 0.19 11.8 0.2 1.4 1 1 0 1 1 1 0 Geminivirus rep protein central domain DUF3138 PF11336.8 CDJ39968.1 - 0.65 8.5 5.8 0.76 8.3 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Shadoo PF14999.6 CDJ39968.1 - 1.4 9.0 10.4 1.9 8.6 10.4 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective IHABP4_N PF16174.5 CDJ39968.1 - 2.7 8.6 7.9 6.5 7.3 3.8 2.0 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal AP2 PF00847.20 CDJ39969.1 - 0.1 12.9 2.8 6.8 7.0 0.2 3.6 3 0 0 3 3 3 0 AP2 domain Peptidase_C97 PF05903.14 CDJ39971.1 - 4.1e-13 49.4 0.2 6.9e-13 48.7 0.2 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain UBA PF00627.31 CDJ39971.1 - 1.7e-08 34.2 1.2 1.7e-08 34.2 1.2 2.0 2 0 0 2 2 2 1 UBA/TS-N domain PUB PF09409.10 CDJ39971.1 - 1.9e-06 27.7 0.0 1.6e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 PUB domain DUF1796 PF08795.10 CDJ39971.1 - 0.0063 16.5 0.2 0.012 15.6 0.2 1.9 1 1 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) HOIP-UBA PF16678.5 CDJ39971.1 - 0.024 14.7 2.5 0.067 13.2 2.5 1.9 1 1 0 1 1 1 0 HOIP UBA domain pair CUE PF02845.16 CDJ39971.1 - 0.046 13.4 1.8 0.083 12.6 0.2 2.2 2 0 0 2 2 2 0 CUE domain DUF2344 PF10105.9 CDJ39971.1 - 0.33 10.8 1.8 0.97 9.3 1.9 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) LRAT PF04970.13 CDJ39971.1 - 0.39 11.0 1.7 0.54 10.6 0.3 1.8 2 0 0 2 2 2 0 Lecithin retinol acyltransferase DUF4813 PF16072.5 CDJ39971.1 - 0.42 10.2 38.4 0.32 10.6 16.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) DUF4358 PF14270.6 CDJ39971.1 - 1 9.7 2.8 7.9 6.8 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4358) bZIP_1 PF00170.21 CDJ39971.1 - 1.3 9.2 7.0 0.2 11.8 1.0 2.5 3 0 0 3 3 3 0 bZIP transcription factor Aft1_HRA PF11786.8 CDJ39971.1 - 7.1 7.1 7.4 0.69 10.3 1.4 2.5 2 2 0 2 2 2 0 Aft1 HRA domain Activator_LAG-3 PF11498.8 CDJ39972.1 - 2.5 6.9 41.7 0.4 9.6 29.1 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Pkinase PF00069.25 CDJ39973.1 - 6.2e-06 25.8 0.0 3.2e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ39973.1 - 0.0062 15.9 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Roughex PF06020.11 CDJ39973.1 - 0.22 10.6 0.9 0.4 9.7 0.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein YqfQ PF14181.6 CDJ39973.1 - 0.28 11.4 0.0 0.28 11.4 0.0 2.5 3 0 0 3 3 3 0 YqfQ-like protein SR-25 PF10500.9 CDJ39974.1 - 0.006 16.2 14.9 0.013 15.1 14.9 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Smg8_Smg9 PF10220.9 CDJ39974.1 - 0.047 12.0 7.7 0.057 11.7 7.7 1.2 1 0 0 1 1 1 0 Smg8_Smg9 Peptidase_S64 PF08192.11 CDJ39974.1 - 0.067 11.7 10.4 0.11 10.9 10.4 1.3 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 CDJ39974.1 - 0.082 10.0 12.9 0.095 9.8 12.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CDJ39974.1 - 0.092 11.3 14.0 0.011 14.4 8.0 1.9 2 0 0 2 2 2 0 Macoilin family LCD1 PF09798.9 CDJ39974.1 - 0.13 10.8 6.5 0.18 10.3 6.5 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Presenilin PF01080.17 CDJ39974.1 - 0.25 10.1 15.0 0.056 12.2 11.9 1.5 2 0 0 2 2 2 0 Presenilin Caudo_TAP PF02413.17 CDJ39974.1 - 0.59 10.3 15.2 2.2 8.5 10.2 2.4 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK Gti1_Pac2 PF09729.9 CDJ39974.1 - 0.59 10.2 9.7 1.9 8.6 9.7 1.8 2 0 0 2 2 2 0 Gti1/Pac2 family Hrs_helical PF12210.8 CDJ39974.1 - 0.7 10.5 13.9 0.2 12.2 6.4 2.3 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate UPF0524 PF15823.5 CDJ39974.1 - 0.84 9.0 6.9 0.07 12.5 1.9 1.7 2 0 0 2 2 2 0 UPF0524 of C3orf70 Miga PF10265.9 CDJ39974.1 - 0.99 8.3 10.9 1.4 7.8 10.9 1.2 1 0 0 1 1 1 0 Mitoguardin Plasmodium_Vir PF05795.11 CDJ39974.1 - 1.3 8.3 7.1 1.9 7.9 7.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Menin PF05053.13 CDJ39974.1 - 1.4 7.2 9.7 2.1 6.6 9.7 1.3 1 0 0 1 1 1 0 Menin Apt1 PF10351.9 CDJ39974.1 - 1.5 7.6 12.0 2.3 6.9 12.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain MPM1 PF17234.2 CDJ39974.1 - 2.6 8.3 18.2 0.12 12.6 11.5 2.0 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 MMR1 PF08505.10 CDJ39974.1 - 2.6 8.3 19.4 0.35 11.1 13.6 2.0 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein CCDC106 PF15794.5 CDJ39974.1 - 3.1 7.4 14.8 6.6 6.4 14.8 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Mem_trans PF03547.18 CDJ39974.1 - 3.3 6.0 7.9 4.8 5.5 7.9 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF4746 PF15928.5 CDJ39974.1 - 3.7 6.9 7.9 12 5.2 7.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF4692 PF15763.5 CDJ39974.1 - 4.8 7.6 11.8 9.6 6.6 11.8 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Sec62 PF03839.16 CDJ39974.1 - 5.7 6.4 8.6 13 5.3 8.6 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 CDJ39974.1 - 5.8 5.6 12.4 8.9 5.0 12.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Lin-8 PF03353.15 CDJ39974.1 - 6.6 6.2 24.8 1.9 8.0 17.5 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Hid1 PF12722.7 CDJ39974.1 - 8 4.4 13.3 9.3 4.2 13.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spt20 PF12090.8 CDJ39975.1 - 0.1 12.2 2.4 0.11 12.1 2.4 1.0 1 0 0 1 1 1 0 Spt20 family Tegument_dsDNA PF12818.7 CDJ39975.1 - 0.69 9.0 4.0 0.74 8.9 4.0 1.0 1 0 0 1 1 1 0 dsDNA viral tegument protein RR_TM4-6 PF06459.12 CDJ39976.1 - 0.063 13.1 14.8 0.077 12.8 14.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Velvet PF11754.8 CDJ39976.1 - 0.14 12.0 14.5 0.17 11.8 14.5 1.0 1 0 0 1 1 1 0 Velvet factor SID-1_RNA_chan PF13965.6 CDJ39976.1 - 0.16 10.3 3.1 0.17 10.3 3.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Cellulose_synt PF03552.14 CDJ39976.1 - 0.26 9.7 6.5 0.33 9.4 6.5 1.1 1 0 0 1 1 1 0 Cellulose synthase MAJIN PF15077.6 CDJ39976.1 - 0.88 9.3 12.0 0.93 9.2 12.0 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein Neur_chan_memb PF02932.16 CDJ39976.1 - 1.6 8.7 13.2 1.8 8.6 13.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Gti1_Pac2 PF09729.9 CDJ39976.1 - 1.9 8.6 12.8 2.2 8.3 12.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Sec62 PF03839.16 CDJ39976.1 - 2.1 7.8 13.4 2.5 7.5 13.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4407 PF14362.6 CDJ39976.1 - 2.2 7.6 13.5 2.7 7.3 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 CDJ39976.1 - 2.9 7.8 43.4 3.7 7.4 43.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop53 PF07767.11 CDJ39976.1 - 3.4 6.9 22.2 4.2 6.7 22.2 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Presenilin PF01080.17 CDJ39976.1 - 4.4 6.0 21.2 5.2 5.7 21.2 1.0 1 0 0 1 1 1 0 Presenilin STAC2_u1 PF16664.5 CDJ39976.1 - 4.6 7.7 11.9 7.2 7.1 11.9 1.3 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Membralin PF09746.9 CDJ39976.1 - 5.9 5.8 11.1 7.9 5.4 11.1 1.2 1 0 0 1 1 1 0 Tumour-associated protein ALMT PF11744.8 CDJ39976.1 - 6.3 5.5 14.0 7.3 5.3 14.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Hydin_ADK PF17213.3 CDJ39976.1 - 6.5 7.0 16.7 8.3 6.6 16.7 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Exonuc_VII_L PF02601.15 CDJ39976.1 - 6.5 6.2 20.1 7.4 6.0 20.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Zip PF02535.22 CDJ39976.1 - 6.6 5.8 14.9 7.9 5.6 14.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.9 CDJ39976.1 - 7.1 4.8 33.4 8.3 4.5 33.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.16 CDJ39976.1 - 8.1 5.2 8.4 8.2 5.2 8.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein BORG_CEP PF14957.6 CDJ39976.1 - 9.6 7.4 13.1 12 7.0 13.1 1.1 1 0 0 1 1 1 0 Cdc42 effector Phage_Gp23 PF10669.9 CDJ39976.1 - 9.8 6.5 9.5 13 6.1 9.5 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF1635 PF07795.11 CDJ39978.1 - 0.023 14.5 4.4 0.023 14.5 4.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) CCDC117 PF15810.5 CDJ39978.1 - 0.17 12.2 0.3 0.17 12.2 0.3 2.8 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 117 DUF4781 PF16013.5 CDJ39978.1 - 0.6 8.9 2.4 1 8.1 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) PIEZO PF15917.5 CDJ39978.1 - 5.6 6.4 15.3 1.5 8.3 10.0 2.0 2 0 0 2 2 2 0 Piezo Hydin_ADK PF17213.3 CDJ39978.1 - 5.8 7.2 8.0 2 8.7 2.3 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Suf PF05843.14 CDJ39980.1 - 0.0013 18.8 9.4 0.0016 18.4 9.4 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ39980.1 - 0.011 15.7 26.9 0.012 15.6 26.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EIF4E-T PF10477.9 CDJ39980.1 - 0.013 14.4 8.6 0.015 14.2 8.6 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Orf78 PF06024.12 CDJ39980.1 - 0.026 14.8 3.1 0.031 14.6 1.0 1.8 2 0 0 2 2 2 0 Orf78 (ac78) DDHD PF02862.17 CDJ39980.1 - 0.028 14.6 2.4 0.032 14.4 2.4 1.1 1 0 0 1 1 1 0 DDHD domain DUF2126 PF09899.9 CDJ39980.1 - 0.051 11.6 1.1 0.059 11.4 1.1 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF2076 PF09849.9 CDJ39980.1 - 0.056 13.5 25.5 0.087 12.9 25.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FAM91_C PF14648.6 CDJ39980.1 - 0.058 12.2 3.1 0.07 12.0 3.1 1.1 1 0 0 1 1 1 0 FAM91 C-terminus ANAPC_CDC26 PF10471.9 CDJ39980.1 - 0.14 13.0 29.0 1.5 9.8 19.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Peptidase_M16 PF00675.20 CDJ39980.1 - 0.14 12.1 0.0 0.14 12.1 0.0 2.2 1 1 1 2 2 1 0 Insulinase (Peptidase family M16) PIP5K PF01504.18 CDJ39980.1 - 0.15 11.2 3.1 0.2 10.8 3.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase MMR1 PF08505.10 CDJ39980.1 - 0.16 12.2 10.0 0.21 11.8 10.0 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4330 PF14221.6 CDJ39980.1 - 0.27 11.5 1.8 0.43 10.8 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) V_ATPase_I PF01496.19 CDJ39980.1 - 0.28 9.1 6.3 0.35 8.8 6.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Conotoxin PF02950.17 CDJ39980.1 - 0.41 11.7 12.7 0.18 12.9 7.8 2.2 2 0 0 2 2 2 0 Conotoxin PAS PF00989.25 CDJ39980.1 - 0.44 10.6 4.4 0.42 10.6 0.5 2.1 1 1 1 2 2 2 0 PAS fold ORC_WH_C PF18137.1 CDJ39980.1 - 0.66 10.0 8.2 0.92 9.6 8.2 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF2722 PF10846.8 CDJ39980.1 - 0.75 8.7 29.1 0.048 12.6 18.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 CDJ39980.1 - 1.4 7.9 12.2 1.8 7.4 12.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ39980.1 - 1.8 8.6 4.8 2.4 8.2 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Caudo_TAP PF02413.17 CDJ39980.1 - 1.8 8.7 11.8 2.6 8.2 11.8 1.2 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Het-C PF07217.11 CDJ39980.1 - 1.9 6.9 7.9 2.5 6.5 7.9 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C FIST_C PF10442.9 CDJ39980.1 - 2.1 8.3 11.5 0.15 12.0 0.5 2.1 1 1 1 2 2 2 0 FIST C domain DUF3292 PF11696.8 CDJ39980.1 - 3.6 5.8 7.3 4.6 5.5 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF2489 PF10675.9 CDJ39980.1 - 4 7.4 16.5 14 5.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Presenilin PF01080.17 CDJ39980.1 - 4.9 5.8 10.6 6.6 5.4 10.6 1.1 1 0 0 1 1 1 0 Presenilin DUF3499 PF12005.8 CDJ39980.1 - 5.7 7.6 12.1 2.9e+02 2.0 12.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3499) AAA PF00004.29 CDJ39981.1 - 6.9e-12 45.9 0.0 1.1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ39981.1 - 4.8e-10 40.1 0.0 6.3e-08 33.2 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 CDJ39981.1 - 1.6e-05 24.9 0.1 0.0049 16.8 0.0 2.0 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CDJ39981.1 - 0.00015 21.3 0.0 0.00028 20.4 0.0 1.3 1 1 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 CDJ39981.1 - 0.00021 20.7 0.1 0.031 13.7 0.1 2.1 1 1 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 CDJ39981.1 - 0.0003 21.1 0.0 0.0019 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDJ39981.1 - 0.0012 18.6 0.7 0.43 10.3 0.1 2.2 1 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ39981.1 - 0.0014 18.6 0.1 0.0043 17.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 CDJ39981.1 - 0.0062 16.5 0.0 0.02 14.9 0.0 1.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CDJ39981.1 - 0.012 14.9 0.9 0.08 12.1 0.4 1.8 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_14 PF13173.6 CDJ39981.1 - 0.013 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CDJ39981.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 CDJ39981.1 - 0.033 14.5 1.5 0.17 12.2 0.2 2.1 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 CDJ39981.1 - 0.036 14.6 0.0 0.056 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CDJ39981.1 - 0.04 13.8 0.0 0.071 13.0 0.0 1.3 1 1 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 CDJ39981.1 - 0.072 12.4 0.3 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 CDJ39981.1 - 0.083 12.0 0.1 0.27 10.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 CDJ39981.1 - 0.088 13.2 0.1 0.15 12.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDJ39981.1 - 0.089 12.5 0.1 0.12 12.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CDJ39981.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDJ39981.1 - 0.19 12.2 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Dehydrin PF00257.19 CDJ39982.1 - 0.03 14.9 5.8 0.048 14.2 5.8 1.4 1 1 0 1 1 1 0 Dehydrin Vps8 PF12816.7 CDJ39983.1 - 0.0014 18.2 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Ribosomal_60s PF00428.19 CDJ39983.1 - 0.018 15.6 12.9 0.023 15.3 12.9 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein TraG_N PF07916.11 CDJ39983.1 - 0.4 9.5 3.4 0.43 9.4 3.4 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF3138 PF11336.8 CDJ39983.1 - 6.7 5.2 7.4 6.6 5.2 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Leu_zip PF15294.6 CDJ39984.1 - 0.11 12.0 6.4 0.035 13.6 3.0 1.7 2 0 0 2 2 2 0 Leucine zipper PRCC PF10253.9 CDJ39986.1 - 2.5e-14 54.6 23.8 2.5e-14 54.6 23.8 3.6 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting SPX PF03105.19 CDJ39986.1 - 0.064 13.2 21.0 0.03 14.3 11.0 2.3 2 0 0 2 2 2 0 SPX domain PIEZO PF15917.5 CDJ39986.1 - 0.07 12.6 5.5 0.13 11.7 5.5 1.5 1 0 0 1 1 1 0 Piezo Lin-8 PF03353.15 CDJ39986.1 - 1.5 8.3 10.8 3.3 7.2 10.8 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ecl1 PF12855.7 CDJ39986.1 - 8.5 7.5 26.6 14 6.8 1.7 2.5 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins CDK2AP PF09806.9 CDJ39987.1 - 0.0056 16.8 2.8 0.008 16.3 2.8 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein WSD PF15613.6 CDJ39987.1 - 0.05 14.1 0.1 0.058 13.9 0.1 1.2 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF4589 PF15252.6 CDJ39987.1 - 0.051 13.6 0.4 0.06 13.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) SR-25 PF10500.9 CDJ39987.1 - 7.8 6.0 13.0 13 5.3 13.0 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein TALPID3 PF15324.6 CDJ39989.1 - 7.7 4.0 12.7 9.5 3.7 12.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Pro_isomerase PF00160.21 CDJ39990.1 - 1.8e-08 34.8 0.0 2.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_60s PF00428.19 CDJ39990.1 - 1.7e-05 25.3 2.0 1.7e-05 25.3 2.0 2.9 3 0 0 3 3 3 1 60s Acidic ribosomal protein Herpes_UL17 PF04559.12 CDJ39990.1 - 0.25 10.1 1.3 0.28 9.9 1.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein SUIM_assoc PF16619.5 CDJ39991.1 - 0.021 14.9 0.0 0.021 14.9 0.0 6.5 4 2 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 BLI1 PF17324.2 CDJ39992.1 - 0.14 12.8 0.6 0.36 11.5 0.0 1.8 2 0 0 2 2 2 0 BLOC-1 interactor 1 DUF4391 PF14335.6 CDJ39992.1 - 0.2 11.3 1.4 0.26 11.0 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DUF327 PF03885.13 CDJ39992.1 - 0.34 10.9 2.4 13 5.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF327) HrpJ PF07201.11 CDJ39992.1 - 0.8 10.0 11.1 3.9 7.7 1.3 2.1 2 0 0 2 2 2 0 HrpJ-like domain SARAF PF06682.12 CDJ39993.1 - 1.5 8.4 9.3 0.041 13.5 1.4 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis WD40 PF00400.32 CDJ39994.1 - 0.00084 20.1 0.0 0.011 16.6 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ39994.1 - 0.0052 17.1 0.0 4.8 7.6 0.0 2.3 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain CDC50 PF03381.15 CDJ39995.1 - 8.3e-20 71.4 0.0 1e-19 71.1 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Herpes_LMP1 PF05297.11 CDJ39995.1 - 0.079 12.2 0.9 0.11 11.6 0.9 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2722 PF10846.8 CDJ39996.1 - 0.0016 17.5 9.6 0.0019 17.3 9.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF3886 PF13025.6 CDJ39996.1 - 0.19 11.9 11.7 0.28 11.4 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Maf1 PF09174.10 CDJ39996.1 - 0.33 11.1 3.7 0.43 10.7 3.7 1.1 1 0 0 1 1 1 0 Maf1 regulator Spt20 PF12090.8 CDJ39996.1 - 0.45 10.1 17.7 0.46 10.1 17.7 1.1 1 0 0 1 1 1 0 Spt20 family EIF4E-T PF10477.9 CDJ39996.1 - 0.86 8.3 10.7 0.99 8.1 10.7 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E MctB PF11382.8 CDJ39996.1 - 1.9 8.1 7.4 2.5 7.7 7.4 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB TFIIA PF03153.13 CDJ39996.1 - 5.5 6.9 18.6 5.5 6.9 18.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ipi1_N PF12333.8 CDJ39997.1 - 0.22 12.1 2.7 11 6.7 0.2 2.6 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation SR-25 PF10500.9 CDJ39997.1 - 0.88 9.1 18.8 1.1 8.9 5.9 2.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF1968 PF09291.10 CDJ39997.1 - 1.4 9.1 5.6 0.2 11.7 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1968) ANAPC_CDC26 PF10471.9 CDJ39997.1 - 1.8 9.5 9.2 3.5 8.5 2.6 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 RAP PF08373.10 CDJ39998.1 - 0.0013 18.8 2.4 0.0013 18.8 0.0 2.1 2 0 0 2 2 2 1 RAP domain CPSF100_C PF13299.6 CDJ39998.1 - 0.02 15.1 4.3 0.034 14.3 4.3 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Connexin PF00029.19 CDJ39998.1 - 1.6 8.4 4.0 2.4 7.9 4.0 1.2 1 0 0 1 1 1 0 Connexin Macoilin PF09726.9 CDJ39998.1 - 2.6 6.5 13.2 3.9 5.9 13.2 1.2 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CDJ39998.1 - 3.4 6.3 9.9 4.7 5.9 9.9 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CDJ39998.1 - 4.9 5.9 12.4 6.3 5.5 12.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4770 PF15994.5 CDJ39998.1 - 6.2 7.0 10.7 0.54 10.5 5.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) TERB2 PF15101.6 CDJ39998.1 - 6.8 6.7 12.3 0.41 10.7 7.3 1.5 2 0 0 2 2 2 0 Telomere-associated protein TERB2 TauE PF01925.19 CDJ39999.1 - 7.2e-09 35.6 9.5 7.2e-09 35.6 9.5 2.8 4 0 0 4 4 4 2 Sulfite exporter TauE/SafE SARAF PF06682.12 CDJ39999.1 - 0.0021 17.8 2.3 0.0021 17.8 2.3 2.5 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis CoA_binding_3 PF13727.6 CDJ39999.1 - 0.006 16.6 3.7 0.021 14.8 0.3 2.6 2 0 0 2 2 2 1 CoA-binding domain TMEM208_SND2 PF05620.11 CDJ39999.1 - 0.028 14.2 0.2 0.028 14.2 0.2 4.5 3 1 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 OAD_gamma PF04277.13 CDJ39999.1 - 0.22 12.1 0.0 0.22 12.1 0.0 4.7 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4179 PF13786.6 CDJ39999.1 - 0.57 10.7 5.1 0.64 10.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) AMP-binding PF00501.28 CDJ39999.1 - 3.6 6.1 10.9 0.15 10.7 3.3 2.1 1 1 1 2 2 2 0 AMP-binding enzyme DUF3375 PF11855.8 CDJ40000.1 - 0.0015 17.6 2.4 0.0016 17.5 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) AF-4 PF05110.13 CDJ40000.1 - 0.034 12.3 14.7 0.036 12.2 14.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TPR_20 PF14561.6 CDJ40000.1 - 0.034 14.5 4.2 0.072 13.4 4.2 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat SAP25 PF15476.6 CDJ40000.1 - 0.056 13.1 3.8 0.063 12.9 3.8 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 Urb2 PF10441.9 CDJ40000.1 - 0.13 12.2 1.8 0.14 12.1 1.8 1.1 1 0 0 1 1 1 0 Urb2/Npa2 family Herpes_pp85 PF04637.12 CDJ40000.1 - 0.31 9.4 2.5 0.33 9.3 2.5 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) CCDC24 PF15669.5 CDJ40000.1 - 1.4 8.7 13.0 2.5 8.0 13.0 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family SR-25 PF10500.9 CDJ40000.1 - 1.4 8.5 15.1 1.1 8.8 14.5 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ40001.1 - 0.0091 16.3 2.1 0.0091 16.3 2.1 2.6 2 1 0 2 2 2 1 Anti-sigma-K factor rskA TACI-CRD2 PF09305.10 CDJ40001.1 - 0.059 13.4 0.3 0.18 11.9 0.3 1.7 1 0 0 1 1 1 0 TACI, cysteine-rich domain DUF3408 PF11888.8 CDJ40001.1 - 0.11 12.6 3.8 0.18 11.9 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Spt20 PF12090.8 CDJ40001.1 - 0.21 11.2 8.6 0.27 10.8 8.6 1.2 1 0 0 1 1 1 0 Spt20 family Vac_Fusion PF02346.16 CDJ40004.1 - 0.0018 17.8 0.2 0.013 15.1 0.2 2.6 1 0 0 1 1 1 1 Chordopoxvirus multifunctional envelope protein A27 FHIPEP PF00771.20 CDJ40005.1 - 0.083 11.4 3.1 1.2 7.5 0.2 2.2 2 0 0 2 2 2 0 FHIPEP family DUF3365 PF11845.8 CDJ40005.1 - 3.1 8.1 8.1 5.8 7.2 3.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3365) Ribosomal_60s PF00428.19 CDJ40005.1 - 5.4 7.7 23.3 1.4 9.6 0.1 4.2 4 0 0 4 4 4 0 60s Acidic ribosomal protein CPSF73-100_C PF11718.8 CDJ40006.1 - 1.6 8.2 3.9 3 7.3 0.1 2.3 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Fra10Ac1 PF09725.9 CDJ40009.1 - 2.3e-07 30.9 0.3 3.3e-05 24.0 0.2 2.3 1 1 1 2 2 2 2 Folate-sensitive fragile site protein Fra10Ac1 Utp14 PF04615.13 CDJ40009.1 - 0.011 14.3 15.4 0.015 13.9 15.4 1.1 1 0 0 1 1 1 0 Utp14 protein PatG_D PF18047.1 CDJ40011.1 - 0.19 12.2 1.0 1.5 9.3 0.1 2.1 2 0 0 2 2 2 0 PatG Domain Peptidase_M14 PF00246.24 CDJ40013.1 - 4.5e-05 23.4 0.0 5e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Tim44 PF04280.15 CDJ40014.1 - 6.9e-12 45.7 1.1 3.1e-11 43.6 0.0 2.4 2 0 0 2 2 2 1 Tim44-like domain TOBE PF03459.17 CDJ40014.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 TOBE domain NPR3 PF03666.13 CDJ40014.1 - 0.074 11.8 8.0 0.045 12.6 5.2 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.15 CDJ40014.1 - 0.13 11.0 6.9 0.19 10.5 6.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FUSC PF04632.12 CDJ40014.1 - 2.7 6.4 29.2 4.6 5.7 29.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family TetR_C_20 PF17925.1 CDJ40014.1 - 4.2 7.7 11.8 0.29 11.4 3.7 3.0 2 1 2 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Robl_LC7 PF03259.17 CDJ40014.1 - 5.6 6.8 7.8 0.98 9.2 0.7 2.4 2 0 0 2 2 2 0 Roadblock/LC7 domain DUF4392 PF14336.6 CDJ40014.1 - 7.6 5.9 6.7 2.3 7.6 3.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) RRM_1 PF00076.22 CDJ40015.1 - 4.6e-06 26.4 0.0 1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PsbW PF07123.12 CDJ40015.1 - 9.9 6.2 7.5 8 6.5 1.3 3.2 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) Pox_A12 PF04651.13 CDJ40016.1 - 0.23 11.5 7.1 0.29 11.2 7.1 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein PAP1 PF08601.10 CDJ40016.1 - 0.98 9.1 13.5 1.1 9.0 13.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF3439 PF11921.8 CDJ40016.1 - 1.9 8.5 10.9 0.75 9.8 8.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) Hamartin PF04388.12 CDJ40016.1 - 9.6 4.7 7.2 11 4.6 7.2 1.0 1 0 0 1 1 1 0 Hamartin protein DUF2722 PF10846.8 CDJ40017.1 - 0.35 9.8 11.4 0.18 10.7 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ40017.1 - 0.83 9.2 19.2 1.9 8.0 2.7 2.0 2 0 0 2 2 2 0 Spt20 family Collagen PF01391.18 CDJ40017.1 - 0.87 9.4 34.8 0.047 13.4 18.0 2.7 2 1 1 3 3 3 0 Collagen triple helix repeat (20 copies) ANAPC_CDC26 PF10471.9 CDJ40017.1 - 4.8 8.1 18.0 2.6 8.9 3.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Preseq_ALAS PF09029.10 CDJ40019.1 - 9.7 6.7 8.2 1.1 9.8 3.1 2.0 2 0 0 2 2 2 0 5-aminolevulinate synthase presequence Dehydrin PF00257.19 CDJ40019.1 - 9.7 6.7 8.2 7.7 7.0 1.4 2.3 2 0 0 2 2 2 0 Dehydrin Cep57_MT_bd PF06657.13 CDJ40020.1 - 0.021 15.2 10.3 0.054 13.9 1.4 2.5 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF3138 PF11336.8 CDJ40020.1 - 0.54 8.8 11.8 0.79 8.3 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) V_ATPase_I PF01496.19 CDJ40020.1 - 0.6 7.9 3.1 4.4 5.1 0.3 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2205 PF10224.9 CDJ40020.1 - 0.81 9.7 12.4 5 7.2 6.1 2.2 2 0 0 2 2 2 0 Short coiled-coil protein Uds1 PF15456.6 CDJ40020.1 - 0.91 9.7 12.0 0.17 12.1 3.1 2.1 2 0 0 2 2 2 0 Up-regulated During Septation Fzo_mitofusin PF04799.13 CDJ40020.1 - 0.98 8.9 10.2 0.4 10.2 3.0 2.1 2 0 0 2 2 2 0 fzo-like conserved region MCU PF04678.13 CDJ40020.1 - 1.1 9.4 6.1 3.8 7.6 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF948 PF06103.11 CDJ40020.1 - 1.2 9.5 4.9 4.1 7.7 1.4 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CDC37_N PF03234.14 CDJ40020.1 - 1.3 9.9 11.0 2 9.3 2.5 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding FapA PF03961.13 CDJ40020.1 - 2.5 6.6 4.5 6.8 5.2 0.1 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A ATP-synt_E PF05680.12 CDJ40020.1 - 3.3 8.1 7.9 0.64 10.4 2.0 2.2 2 0 0 2 2 2 0 ATP synthase E chain DUF1043 PF06295.12 CDJ40020.1 - 3.4 7.7 14.8 3.4 7.7 4.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Tropomyosin_1 PF12718.7 CDJ40020.1 - 4.4 7.4 13.3 0.29 11.3 2.2 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF755 PF05501.11 CDJ40020.1 - 4.5 7.6 11.8 1.5 9.1 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Laminin_II PF06009.12 CDJ40020.1 - 8.4 6.4 10.4 2.4 8.2 2.4 2.2 2 0 0 2 2 2 0 Laminin Domain II SR-25 PF10500.9 CDJ40021.1 - 5.5e-05 22.9 11.6 7.7e-05 22.4 11.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Peptidase_S64 PF08192.11 CDJ40021.1 - 0.035 12.6 3.5 0.041 12.4 3.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 AF-4 PF05110.13 CDJ40021.1 - 0.044 11.9 15.4 0.058 11.5 15.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein IQCJ-SCHIP1 PF15157.6 CDJ40021.1 - 0.05 13.4 6.8 0.076 12.8 6.8 1.2 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Macoilin PF09726.9 CDJ40021.1 - 0.064 11.8 1.9 0.073 11.6 1.9 1.1 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CDJ40021.1 - 0.1 12.6 6.6 0.12 12.3 6.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM199X PF15814.5 CDJ40021.1 - 0.23 10.5 9.3 0.32 10.0 9.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X ATG16 PF08614.11 CDJ40021.1 - 0.47 10.7 7.5 0.78 9.9 7.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SSP160 PF06933.11 CDJ40021.1 - 0.49 8.5 9.5 0.6 8.2 9.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 GREB1 PF15782.5 CDJ40021.1 - 2.9 4.9 6.2 3.6 4.6 6.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pap_E4 PF02711.14 CDJ40021.1 - 4.1 8.4 9.7 7.2 7.7 2.2 2.5 2 0 0 2 2 2 0 E4 protein DUF913 PF06025.12 CDJ40022.1 - 0.004 16.2 6.0 0.004 16.2 6.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CDJ40022.1 - 0.0084 14.9 12.8 0.0076 15.1 12.8 1.1 1 0 0 1 1 1 1 Presenilin RR_TM4-6 PF06459.12 CDJ40022.1 - 0.012 15.5 11.5 0.012 15.5 11.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4834 PF16118.5 CDJ40022.1 - 0.013 16.4 9.7 0.013 16.4 9.7 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) PTPRCAP PF15713.5 CDJ40022.1 - 0.018 15.3 14.5 0.021 15.1 14.5 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated ANAPC8 PF04049.13 CDJ40022.1 - 0.042 13.9 7.9 0.064 13.3 7.9 1.4 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 CCDC53 PF10152.9 CDJ40022.1 - 0.042 14.3 13.1 0.046 14.1 13.1 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Serinc PF03348.15 CDJ40022.1 - 0.045 12.7 5.1 0.042 12.8 5.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DDHD PF02862.17 CDJ40022.1 - 0.065 13.4 9.1 0.065 13.4 9.1 1.1 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 CDJ40022.1 - 0.065 12.2 13.7 0.055 12.4 13.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3408 PF11888.8 CDJ40022.1 - 0.07 13.3 13.5 0.092 12.9 13.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) SpoIIP PF07454.11 CDJ40022.1 - 0.076 12.5 14.9 0.086 12.3 14.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 CDJ40022.1 - 0.12 11.3 8.9 0.11 11.6 8.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FHIPEP PF00771.20 CDJ40022.1 - 0.14 10.6 5.4 0.15 10.5 5.4 1.2 1 0 0 1 1 1 0 FHIPEP family SID-1_RNA_chan PF13965.6 CDJ40022.1 - 0.16 10.4 3.2 0.13 10.6 3.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.7 CDJ40022.1 - 0.3 9.2 9.9 0.3 9.2 9.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EOS1 PF12326.8 CDJ40022.1 - 0.45 10.4 3.2 0.4 10.6 3.2 1.2 1 0 0 1 1 1 0 N-glycosylation protein PIP5K PF01504.18 CDJ40022.1 - 0.55 9.4 9.7 0.62 9.2 9.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Connexin PF00029.19 CDJ40022.1 - 0.81 9.4 12.2 1 9.1 12.2 1.1 1 0 0 1 1 1 0 Connexin DUF4175 PF13779.6 CDJ40022.1 - 0.86 7.4 33.4 0.93 7.3 33.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Neur_chan_memb PF02932.16 CDJ40022.1 - 0.99 9.4 10.7 0.98 9.4 10.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ureide_permease PF07168.11 CDJ40022.1 - 1.1 8.0 5.0 1.3 7.7 5.0 1.1 1 0 0 1 1 1 0 Ureide permease AIF_C PF14721.6 CDJ40022.1 - 1.3 9.4 12.7 1.9 8.9 12.7 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FAM60A PF15396.6 CDJ40022.1 - 3.1 7.8 10.2 3.7 7.5 10.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CLN3 PF02487.17 CDJ40022.1 - 3.5 6.6 12.8 4.3 6.3 12.8 1.1 1 0 0 1 1 1 0 CLN3 protein AAA_23 PF13476.6 CDJ40022.1 - 3.6 8.0 20.5 4.1 7.9 20.5 1.1 1 0 0 1 1 1 0 AAA domain Pex14_N PF04695.13 CDJ40022.1 - 4 8.1 26.2 0.43 11.2 22.2 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Plasmodium_Vir PF05795.11 CDJ40022.1 - 4.1 6.7 10.1 4.4 6.6 10.1 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM176 PF14851.6 CDJ40022.1 - 4.3 7.0 13.1 6.2 6.5 13.1 1.2 1 0 0 1 1 1 0 FAM176 family PAT1 PF09770.9 CDJ40022.1 - 4.5 5.4 25.2 4.5 5.4 25.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tim54 PF11711.8 CDJ40022.1 - 4.6 5.9 16.9 5.6 5.6 16.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 OATP PF03137.20 CDJ40022.1 - 4.8 5.3 8.1 5.5 5.1 8.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4407 PF14362.6 CDJ40022.1 - 5 6.4 14.4 6.1 6.1 14.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 CDJ40022.1 - 6.6 4.5 17.2 7.6 4.3 17.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1980 PF09323.10 CDJ40022.1 - 7.3 6.5 10.4 9 6.2 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Kei1 PF08552.11 CDJ40022.1 - 7.8 6.3 14.1 10 5.9 14.1 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 O-antigen_lig PF13425.6 CDJ40022.1 - 9.4 4.9 9.6 11 4.7 9.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3458_C PF17432.2 CDJ40023.1 - 4.2e-19 69.1 0.2 4.5e-19 69.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats ATP11 PF06644.11 CDJ40024.1 - 1.1 9.1 6.7 1.3 8.8 6.7 1.2 1 0 0 1 1 1 0 ATP11 protein Calici_coat PF00915.20 CDJ40024.1 - 1.6 7.5 9.1 2 7.3 9.1 1.3 1 0 0 1 1 1 0 Calicivirus coat protein GET2 PF08690.10 CDJ40024.1 - 5.3 6.6 12.0 5.8 6.5 12.0 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Pex14_N PF04695.13 CDJ40024.1 - 7 7.3 12.8 9.8 6.8 12.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.9 CDJ40026.1 - 8.1 4.9 30.9 19 3.7 30.9 1.5 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 CDJ40027.1 - 5.3e-20 71.4 0.6 0.0058 17.4 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ40027.1 - 0.00025 21.3 0.0 0.27 11.6 0.0 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RskA PF10099.9 CDJ40027.1 - 0.00027 21.3 38.8 0.0008 19.7 7.1 4.1 4 0 0 4 4 4 3 Anti-sigma-K factor rskA Ribosomal_S27e PF01667.17 CDJ40028.1 - 6e-25 86.7 8.1 8.9e-25 86.2 8.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 RAG1_imp_bd PF12560.8 CDJ40028.1 - 0.0042 16.7 4.0 0.0054 16.3 4.0 1.1 1 0 0 1 1 1 1 RAG1 importin binding DUF4407 PF14362.6 CDJ40028.1 - 0.1 11.9 1.7 0.12 11.7 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peroxin-13_N PF04088.13 CDJ40028.1 - 0.12 12.7 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Activator_LAG-3 PF11498.8 CDJ40028.1 - 9.9 5.0 27.9 13 4.6 27.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RNA_pol_N PF01194.17 CDJ40029.1 - 2.2e-32 111.1 0.5 2.6e-32 110.9 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Thioredoxin PF00085.20 CDJ40030.1 - 3.3e-27 94.5 0.1 3.9e-27 94.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CDJ40030.1 - 1.9e-05 25.1 0.2 0.00032 21.1 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CDJ40030.1 - 0.00026 20.7 0.0 0.00028 20.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CDJ40030.1 - 0.00036 20.8 0.0 0.00079 19.7 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 CDJ40030.1 - 0.00092 19.4 0.1 0.0013 18.9 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin KaiB PF07689.12 CDJ40030.1 - 0.0025 17.5 0.0 0.0044 16.7 0.0 1.5 2 0 0 2 2 2 1 KaiB domain Redoxin PF08534.10 CDJ40030.1 - 0.023 14.4 0.3 1.5 8.5 0.1 2.1 1 1 1 2 2 2 0 Redoxin DUF1633 PF07794.11 CDJ40032.1 - 3.8 5.6 14.5 4.4 5.4 14.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) SRA1 PF07304.11 CDJ40033.1 - 0.0074 16.1 0.2 0.01 15.6 0.2 1.3 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) YbgS PF13985.6 CDJ40033.1 - 0.21 11.9 4.3 0.3 11.4 4.3 1.3 1 0 0 1 1 1 0 YbgS-like protein PDEase_I PF00233.19 CDJ40035.1 - 8.1e-62 209.0 0.0 1e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CDJ40035.1 - 0.1 12.8 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 HD domain PDEase_I PF00233.19 CDJ40036.1 - 1.1e-46 159.6 0.1 2e-46 158.6 0.1 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Condensation PF00668.20 CDJ40038.1 - 0.46 9.1 7.6 1.3 7.6 0.0 3.3 4 0 0 4 4 4 0 Condensation domain HEAT PF02985.22 CDJ40039.1 - 0.1 12.9 0.1 1.3 9.5 0.1 3.0 1 0 0 1 1 1 0 HEAT repeat PKS_DE PF18369.1 CDJ40039.1 - 0.11 13.1 0.4 1.1 9.8 0.4 2.9 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain JmjC PF02373.22 CDJ40040.1 - 1.2e-34 119.2 0.6 1.2e-34 119.2 0.6 2.6 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 CDJ40040.1 - 0.0011 18.9 0.1 0.002 18.0 0.1 1.5 1 0 0 1 1 1 1 jmjN domain SPRY PF00622.28 CDJ40041.1 - 0.057 13.5 0.0 9.4 6.4 0.0 3.5 3 0 0 3 3 3 0 SPRY domain TMEM247 PF15444.6 CDJ40041.1 - 7.2 6.6 8.1 8.8 6.3 4.9 2.4 2 0 0 2 2 2 0 Transmembrane protein 247 DEAD PF00270.29 CDJ40042.1 - 2.9e-13 50.0 2.4 5e-13 49.2 0.1 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ40042.1 - 5.8e-09 36.3 0.1 2e-06 28.1 0.0 3.4 1 1 0 2 2 2 1 Helicase conserved C-terminal domain SUIM_assoc PF16619.5 CDJ40042.1 - 0.04 14.0 0.2 0.04 14.0 0.2 30.3 22 6 6 28 28 28 0 Unstructured region C-term to UIM in Ataxin3 cNMP_binding PF00027.29 CDJ40043.1 - 1.1e-44 150.4 0.1 3.2e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Surface_antigen PF11054.8 CDJ40044.1 - 1.1e-25 90.7 0.0 3.5e-25 89.1 0.0 1.7 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen DUF4407 PF14362.6 CDJ40045.1 - 0.015 14.7 2.1 0.017 14.5 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Codanin-1_C PF15296.6 CDJ40045.1 - 0.039 14.0 3.2 0.049 13.7 3.2 1.1 1 0 0 1 1 1 0 Codanin-1 C-terminus AIF_C PF14721.6 CDJ40045.1 - 0.13 12.6 2.5 0.17 12.3 2.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SNF2_N PF00176.23 CDJ40046.1 - 1.2e-51 175.5 0.1 1.2e-51 175.5 0.1 4.6 3 1 1 4 4 4 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ40046.1 - 1.1e-22 80.5 0.0 1.1e-22 80.5 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Chromo PF00385.24 CDJ40046.1 - 8.1e-10 38.5 0.0 2.5e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cdh1_DBD_1 PF18196.1 CDJ40046.1 - 0.011 16.0 0.7 0.011 16.0 0.7 6.2 3 2 1 4 4 4 0 Chromodomain helicase DNA-binding domain 1 CYSTM PF12734.7 CDJ40047.1 - 0.006 16.9 3.8 0.006 16.9 3.8 7.2 6 1 0 6 6 2 1 Cysteine-rich TM module stress tolerance DUF2052 PF09747.9 CDJ40047.1 - 0.0069 16.5 1.5 0.0069 16.5 1.5 3.7 3 1 0 3 3 2 1 Coiled-coil domain containing protein (DUF2052) Frizzled PF01534.17 CDJ40047.1 - 0.008 15.3 0.0 0.05 12.6 0.0 2.0 2 0 0 2 2 2 1 Frizzled/Smoothened family membrane region RskA PF10099.9 CDJ40047.1 - 0.0098 16.2 7.8 0.0098 16.2 7.8 9.3 1 1 2 3 3 1 1 Anti-sigma-K factor rskA DUF4471 PF14740.6 CDJ40047.1 - 0.13 11.4 6.7 0.1 11.8 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) PIG-U PF06728.13 CDJ40047.1 - 0.28 10.2 9.1 0.057 12.5 0.3 2.8 3 0 0 3 3 2 0 GPI transamidase subunit PIG-U OATP PF03137.20 CDJ40047.1 - 0.48 8.7 5.6 0.083 11.2 0.8 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pet20 PF08692.10 CDJ40047.1 - 0.53 11.0 8.5 4.2 8.1 0.1 2.7 3 0 0 3 3 2 0 Mitochondrial protein Pet20 Endostatin PF06482.11 CDJ40047.1 - 0.58 9.6 18.0 0.26 10.7 5.6 2.8 3 0 0 3 3 3 0 Collagenase NC10 and Endostatin Nucleoside_tran PF01733.18 CDJ40047.1 - 0.59 9.5 2.2 1.5 8.2 2.2 1.6 1 0 0 1 1 1 0 Nucleoside transporter Lipase_GDSL PF00657.22 CDJ40047.1 - 0.71 9.8 10.8 20 5.1 0.4 3.2 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase DUF1269 PF06897.12 CDJ40047.1 - 0.75 10.1 0.0 0.75 10.1 0.0 4.6 4 1 0 4 4 3 0 Protein of unknown function (DUF1269) dsRBD2 PF17842.1 CDJ40047.1 - 0.92 9.7 8.2 0.4 10.9 2.1 3.0 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 Med15 PF09606.10 CDJ40047.1 - 1.2 7.7 72.8 0.052 12.2 23.4 2.5 2 1 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4446 PF14584.6 CDJ40047.1 - 1.5 8.8 6.2 0.2 11.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) V_ATPase_I PF01496.19 CDJ40047.1 - 1.5 6.6 15.4 0.0098 13.9 2.9 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FAM176 PF14851.6 CDJ40047.1 - 4.9 6.8 12.5 0.26 10.9 0.3 3.9 4 0 0 4 4 3 0 FAM176 family Spo7 PF03907.13 CDJ40047.1 - 6.9 6.1 7.9 11 5.5 1.0 3.1 3 0 0 3 3 3 0 Spo7-like protein DUF572 PF04502.13 CDJ40047.1 - 8 6.0 23.4 1.4 8.4 6.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF572) eIF-3_zeta PF05091.12 CDJ40047.1 - 9.6 5.0 28.4 5.5 5.9 13.3 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Cpn60_TCP1 PF00118.24 CDJ40048.1 - 1.6e-105 353.6 4.6 9e-75 252.2 0.6 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family ATG_C PF09333.11 CDJ40048.1 - 5.6 7.4 5.9 6.9 7.1 0.9 3.0 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain IHABP4_N PF16174.5 CDJ40049.1 - 0.3 11.7 13.1 0.32 11.6 13.1 1.0 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF3959 PF13105.6 CDJ40049.1 - 3.4 7.1 9.1 4.1 6.8 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF3800 PF12686.7 CDJ40051.1 - 2 9.0 5.8 59 4.3 5.8 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Cyclin_N PF00134.23 CDJ40052.1 - 1.3e-12 47.6 1.0 2.9e-12 46.4 0.3 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDJ40052.1 - 6e-05 23.1 1.3 0.0038 17.3 0.0 3.3 2 2 0 2 2 2 1 Cyclin, C-terminal domain Myosin_head PF00063.21 CDJ40053.1 - 2.1e-72 244.4 10.3 2.9e-71 240.6 0.0 3.3 4 0 0 4 4 4 2 Myosin head (motor domain) Ras PF00071.22 CDJ40053.1 - 4e-30 104.6 0.2 3.9e-29 101.3 0.3 2.6 2 1 0 2 2 2 1 Ras family Roc PF08477.13 CDJ40053.1 - 2.1e-21 76.4 0.9 3.4e-18 66.0 0.0 3.4 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ40053.1 - 3e-08 33.3 1.0 2.2e-07 30.5 0.0 2.8 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ40053.1 - 2.9e-06 26.9 0.0 2.9e-06 26.9 0.0 3.6 5 0 0 5 5 5 1 Elongation factor Tu GTP binding domain IQ PF00612.27 CDJ40053.1 - 0.00085 18.9 38.1 0.048 13.5 1.0 6.5 6 0 0 6 6 6 3 IQ calmodulin-binding motif AAA_5 PF07728.14 CDJ40053.1 - 0.0029 17.6 0.1 0.0076 16.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RskA PF10099.9 CDJ40053.1 - 0.0063 16.8 13.2 0.0063 16.8 13.2 9.3 5 3 3 8 8 8 1 Anti-sigma-K factor rskA Gtr1_RagA PF04670.12 CDJ40053.1 - 0.027 13.8 0.0 0.027 13.8 0.0 2.6 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region AAA PF00004.29 CDJ40053.1 - 0.79 10.2 4.5 3.6 8.0 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Syja_N PF02383.18 CDJ40054.1 - 4.3e-34 118.3 0.0 1.3e-16 60.9 0.0 3.7 3 1 0 3 3 3 2 SacI homology domain RRM_1 PF00076.22 CDJ40057.1 - 1.8e-27 95.0 0.0 6.6e-20 70.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ40057.1 - 0.00039 20.0 0.0 0.0026 17.4 0.0 1.9 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CDJ40057.1 - 0.061 13.6 0.1 11 6.2 0.0 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 CDJ40057.1 - 0.069 13.2 0.5 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CDJ40057.1 - 0.092 12.6 0.1 2.8 7.9 0.1 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif SR-25 PF10500.9 CDJ40057.1 - 0.3 10.7 4.8 0.36 10.4 4.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ40057.1 - 2.2 8.6 9.6 1.1 9.6 7.2 1.7 1 1 1 2 2 2 0 Early growth response N-terminal domain Dehydrin PF00257.19 CDJ40062.1 - 5.8 7.5 6.1 1.3 9.6 2.8 1.5 2 0 0 2 2 2 0 Dehydrin TPR_19 PF14559.6 CDJ40063.1 - 2.8e-07 30.9 0.3 2.8e-07 30.9 0.3 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat SART-1 PF03343.13 CDJ40063.1 - 0.0021 16.7 0.7 0.0026 16.4 0.7 1.1 1 0 0 1 1 1 1 SART-1 family TPR_9 PF13371.6 CDJ40063.1 - 0.032 14.4 0.7 0.032 14.4 0.7 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SR-25 PF10500.9 CDJ40063.1 - 0.93 9.1 23.9 1.8 8.1 2.2 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.13 CDJ40064.1 - 2.3 7.2 28.6 2.6 7.0 28.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CDJ40064.1 - 2.6 8.0 52.0 2.7 7.9 52.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 CDJ40065.1 - 0.00014 20.8 6.5 0.00018 20.5 6.5 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain TPR_2 PF07719.17 CDJ40065.1 - 0.0023 17.9 0.7 0.0023 17.9 0.7 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ40065.1 - 0.0068 16.2 0.4 0.052 13.4 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ40065.1 - 0.028 15.2 2.4 0.028 15.2 2.4 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat YbjQ_1 PF01906.17 CDJ40065.1 - 0.034 14.8 0.3 0.087 13.5 0.0 1.8 2 0 0 2 2 2 0 Putative heavy-metal-binding TPR_12 PF13424.6 CDJ40065.1 - 2.3 8.6 16.3 0.46 10.8 0.4 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Peptidase_S64 PF08192.11 CDJ40065.1 - 3.3 6.1 16.3 5 5.5 16.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 TPR_6 PF13174.6 CDJ40065.1 - 9.8 7.1 7.2 8.9 7.2 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RNA_lig_T4_1 PF09511.10 CDJ40068.1 - 0.27 11.0 0.5 0.35 10.7 0.5 1.1 1 0 0 1 1 1 0 RNA ligase Spt20 PF12090.8 CDJ40068.1 - 0.73 9.4 13.1 0.92 9.1 13.1 1.1 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ40068.1 - 1.1 7.9 3.9 1.4 7.6 3.9 1.0 1 0 0 1 1 1 0 Presenilin DUF2802 PF10975.8 CDJ40070.1 - 3 8.0 12.8 0.67 10.1 4.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Pkinase_Tyr PF07714.17 CDJ40072.1 - 0.00015 21.1 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_60s PF00428.19 CDJ40072.1 - 0.0043 17.6 2.9 0.0053 17.3 2.9 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pkinase PF00069.25 CDJ40072.1 - 0.017 14.5 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain CGI-121 PF08617.10 CDJ40072.1 - 0.16 12.1 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase binding protein CGI-121 CCSAP PF15748.5 CDJ40073.1 - 0.043 14.0 7.1 0.051 13.7 7.1 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Spt20 PF12090.8 CDJ40073.1 - 0.14 11.8 6.7 0.17 11.5 6.7 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ40073.1 - 0.22 11.5 8.4 0.27 11.2 8.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4179 PF13786.6 CDJ40073.1 - 3.7 8.1 0.0 3.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Chorion_2 PF03964.15 CDJ40074.1 - 1.8 9.4 9.4 1.9 9.4 9.4 1.1 1 0 0 1 1 1 0 Chorion family 2 IMUP PF15761.5 CDJ40074.1 - 4.1 8.2 11.3 4.3 8.1 11.3 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF2722 PF10846.8 CDJ40076.1 - 0.0019 17.2 1.6 0.0019 17.2 1.6 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ40076.1 - 0.14 12.1 56.7 0.7 9.8 20.7 3.9 3 1 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ40076.1 - 0.38 11.0 0.0 0.38 11.0 0.0 7.7 2 2 2 6 6 6 0 Anti-sigma-K factor rskA TPR_2 PF07719.17 CDJ40077.1 - 1e-09 37.7 9.9 0.0032 17.4 1.6 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ40077.1 - 2.6e-09 36.6 0.1 0.0029 17.2 0.0 2.8 2 1 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 CDJ40077.1 - 1.3e-08 35.4 41.5 0.00015 22.3 16.8 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ40077.1 - 9.9e-08 32.2 16.2 0.004 17.9 5.8 4.0 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ40077.1 - 4.6e-07 29.5 1.3 0.015 15.5 0.3 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ40077.1 - 2.2e-06 27.7 9.9 0.0052 16.9 4.5 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ40077.1 - 2.6e-06 27.0 5.5 0.31 10.9 0.3 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ40077.1 - 0.00039 20.6 0.3 0.063 13.7 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ40077.1 - 0.00096 19.6 14.5 0.0021 18.6 8.1 2.6 1 1 2 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 CDJ40077.1 - 0.0099 16.3 4.0 1.7 9.1 0.8 2.4 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_12 PF13424.6 CDJ40077.1 - 0.05 13.9 14.9 1.6 9.0 3.6 3.6 1 1 2 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 CDJ40077.1 - 0.15 10.9 0.4 0.63 8.9 0.4 1.8 1 1 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 CDJ40077.1 - 2.2 8.5 6.3 9.1 6.6 0.3 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_60s PF00428.19 CDJ40077.1 - 3.4 8.3 9.4 8.5 7.0 9.4 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein TPR_6 PF13174.6 CDJ40077.1 - 9.3 7.1 10.5 26 5.7 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TauE PF01925.19 CDJ40079.1 - 3e-13 50.0 9.2 3e-13 50.0 9.2 2.3 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE APC1_C PF18122.1 CDJ40079.1 - 0.099 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain DUF2722 PF10846.8 CDJ40079.1 - 1.4 7.8 7.7 3.3 6.5 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) DUF4179 PF13786.6 CDJ40083.1 - 1 9.9 8.0 0.24 11.9 1.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) CcmF_C PF16327.5 CDJ40083.1 - 1.7 7.9 5.8 14 4.8 2.0 2.3 2 0 0 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal RIBIOP_C PF04950.12 CDJ40083.1 - 3.1 7.1 6.1 5.9 6.2 6.1 1.4 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal SR-25 PF10500.9 CDJ40084.1 - 3.9e-06 26.7 13.5 0.0072 16.0 8.5 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Peptidase_M16 PF00675.20 CDJ40084.1 - 5.2e-06 26.5 0.0 5.2e-06 26.5 0.0 2.9 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) tRNA-synt_2d PF01409.20 CDJ40084.1 - 0.021 14.3 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Ndc1_Nup PF09531.10 CDJ40084.1 - 0.064 11.9 12.7 0.0035 16.1 4.5 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup LCD1 PF09798.9 CDJ40084.1 - 0.33 9.4 1.3 1.2 7.5 1.3 1.8 1 1 0 1 1 1 0 DNA damage checkpoint protein Peptidase_S64 PF08192.11 CDJ40084.1 - 2.1 6.7 14.1 3.8 5.9 11.2 2.0 2 0 0 2 2 2 0 Peptidase family S64 Suf PF05843.14 CDJ40084.1 - 4.2 7.3 16.4 5.9 6.8 9.0 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) CCDC53 PF10152.9 CDJ40084.1 - 7.5 7.0 23.3 0.37 11.2 6.3 2.8 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex DUF719 PF05334.13 CDJ40085.1 - 0.0051 17.0 3.6 0.0071 16.6 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF719) eIF-3_zeta PF05091.12 CDJ40085.1 - 0.48 9.3 16.6 0.53 9.2 16.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 CDJ40085.1 - 0.76 9.7 22.9 0.89 9.5 22.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM60A PF15396.6 CDJ40085.1 - 1.7 8.6 12.1 2.1 8.3 12.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF1682 PF07946.14 CDJ40085.1 - 4.7 6.3 15.6 6.2 5.9 15.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RR_TM4-6 PF06459.12 CDJ40085.1 - 5.5 6.7 15.7 6.1 6.6 15.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Serinc PF03348.15 CDJ40085.1 - 6 5.7 6.3 6.1 5.6 6.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFIIA PF03153.13 CDJ40085.1 - 6.7 6.6 39.2 8 6.3 39.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ40085.1 - 9.7 4.8 18.9 11 4.7 18.9 1.0 1 0 0 1 1 1 0 Presenilin AIG1 PF04548.16 CDJ40086.1 - 0.66 9.3 7.7 0.82 9.0 7.7 1.1 1 0 0 1 1 1 0 AIG1 family DUF4446 PF14584.6 CDJ40086.1 - 2.5 8.1 5.1 3.3 7.7 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF932 PF06067.11 CDJ40086.1 - 2.6 7.8 10.5 3.1 7.5 10.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF932) APG9 PF04109.16 CDJ40086.1 - 3 6.8 5.3 6.7 5.6 5.3 1.5 1 1 0 1 1 1 0 Autophagy protein Apg9 FliP PF00813.20 CDJ40086.1 - 4.5 7.1 7.2 0.44 10.4 1.3 1.8 1 1 1 2 2 2 0 FliP family Exonuc_VII_L PF02601.15 CDJ40086.1 - 5.2 6.5 12.7 6.1 6.3 12.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit TFIIA PF03153.13 CDJ40086.1 - 5.4 6.9 18.4 5.5 6.9 18.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleoporin_FG2 PF15967.5 CDJ40088.1 - 0.48 8.9 7.5 0.53 8.8 7.5 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region RskA PF10099.9 CDJ40088.1 - 2.2 8.5 20.8 3.2 8.0 20.8 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4635 PF15466.6 CDJ40089.1 - 0.025 14.1 1.9 0.087 12.3 1.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) Yos1 PF08571.10 CDJ40089.1 - 0.2 11.9 0.2 1.1 9.6 0.2 2.3 1 0 0 1 1 1 0 Yos1-like MCCD1 PF15707.5 CDJ40091.1 - 0.0026 18.2 3.0 0.0026 18.2 3.0 2.8 2 1 1 3 3 3 1 Mitochondrial coiled-coil domain protein 1 Cwf_Cwc_15 PF04889.12 CDJ40091.1 - 0.039 13.7 16.0 0.049 13.4 16.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 CDJ40091.1 - 0.093 11.0 14.3 0.12 10.6 14.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF966 PF06136.13 CDJ40091.1 - 0.12 12.1 17.4 0.14 11.8 17.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SAPS PF04499.15 CDJ40091.1 - 0.2 10.4 10.0 0.25 10.1 10.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 CDJ40091.1 - 0.23 10.3 19.4 0.27 10.1 19.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DNA_pol_phi PF04931.13 CDJ40091.1 - 0.47 8.5 9.2 0.57 8.2 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Lin-8 PF03353.15 CDJ40091.1 - 0.56 9.7 10.4 0.7 9.4 10.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SEEEED PF14797.6 CDJ40091.1 - 0.59 10.3 36.2 0.13 12.4 32.2 1.9 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Dicty_REP PF05086.12 CDJ40091.1 - 1.6 6.6 5.2 1.9 6.3 5.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GREB1 PF15782.5 CDJ40091.1 - 2.8 4.9 13.5 3.3 4.7 13.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S64 PF08192.11 CDJ40091.1 - 3.1 6.2 12.6 3.2 6.1 12.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Neur_chan_memb PF02932.16 CDJ40091.1 - 6 6.8 7.7 8.4 6.4 7.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.6 CDJ40091.1 - 9.7 4.9 14.1 11 4.7 14.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF1631 PF07793.11 CDJ40092.1 - 0.66 8.3 13.7 0.78 8.1 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) TFIIA PF03153.13 CDJ40092.1 - 0.98 9.3 9.3 1.1 9.1 9.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TAF4 PF05236.14 CDJ40093.1 - 0.0093 15.8 14.1 0.0093 15.8 14.1 1.9 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Neur_chan_memb PF02932.16 CDJ40093.1 - 0.18 11.9 4.9 0.29 11.2 4.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 CDJ40093.1 - 0.54 9.4 4.5 0.87 8.7 4.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 CDJ40093.1 - 1.2 7.8 9.5 1.4 7.6 9.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BAF1_ABF1 PF04684.13 CDJ40093.1 - 1.5 7.8 13.3 2.5 7.0 13.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Nop14 PF04147.12 CDJ40093.1 - 1.6 6.8 19.9 2.1 6.5 19.9 1.1 1 0 0 1 1 1 0 Nop14-like family Ndc1_Nup PF09531.10 CDJ40093.1 - 1.7 7.3 6.4 2.5 6.7 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.12 CDJ40093.1 - 3.1 7.6 14.9 4.7 7.0 14.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.11 CDJ40093.1 - 4.6 6.7 15.9 6.1 6.4 15.9 1.1 1 0 0 1 1 1 0 PPP4R2 Spt20 PF12090.8 CDJ40093.1 - 4.8 6.7 13.8 7 6.2 13.8 1.2 1 0 0 1 1 1 0 Spt20 family GREB1 PF15782.5 CDJ40093.1 - 5 4.1 7.6 5.6 3.9 7.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCSAP PF15748.5 CDJ40093.1 - 6 7.0 20.5 2 8.5 17.8 1.5 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated TFIIA PF03153.13 CDJ40098.1 - 0.018 15.1 22.1 0.019 15.0 22.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DFF40 PF09230.10 CDJ40098.1 - 0.02 14.5 0.4 0.019 14.6 0.4 1.1 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa Hydin_ADK PF17213.3 CDJ40098.1 - 0.032 14.5 5.7 0.053 13.8 5.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain PRMT5_TIM PF17285.2 CDJ40098.1 - 0.038 13.2 1.5 0.087 12.0 1.4 1.8 1 1 0 1 1 1 0 PRMT5 TIM barrel domain DUF572 PF04502.13 CDJ40098.1 - 0.16 11.6 7.9 0.24 11.0 7.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S46 PF10459.9 CDJ40098.1 - 0.28 9.8 10.9 0.27 9.9 10.9 1.1 1 0 0 1 1 1 0 Peptidase S46 NUP PF06516.11 CDJ40098.1 - 0.31 10.2 3.1 0.49 9.6 3.1 1.3 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) DUF1788 PF08747.11 CDJ40098.1 - 0.76 9.8 4.6 4 7.5 4.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1788) V_ATPase_I PF01496.19 CDJ40098.1 - 1.3 6.8 8.6 1.5 6.7 8.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AsmA_2 PF13502.6 CDJ40098.1 - 4.9 6.6 6.7 0.95 8.9 2.1 2.0 2 0 0 2 2 2 0 AsmA-like C-terminal region UCH PF00443.29 CDJ40098.1 - 4.9 6.6 9.9 5.6 6.4 9.9 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase TMPIT PF07851.13 CDJ40098.1 - 5.1 6.3 9.7 6.3 6.0 9.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.9 CDJ40098.1 - 6.3 5.8 17.3 8.4 5.4 17.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phostensin_N PF13916.6 CDJ40100.1 - 2.8 8.3 15.3 0.71 10.2 2.3 2.3 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal LIM_bind PF01803.16 CDJ40100.1 - 3.7 7.0 17.5 0.036 13.6 3.3 2.0 1 1 1 2 2 2 0 LIM-domain binding protein GET2 PF08690.10 CDJ40100.1 - 5.7 6.5 10.5 7.4 6.2 10.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Presenilin PF01080.17 CDJ40100.1 - 7.2 5.3 7.6 8.8 5.0 7.6 1.1 1 0 0 1 1 1 0 Presenilin Presenilin PF01080.17 CDJ40101.1 - 0.014 14.2 3.0 0.021 13.6 3.0 1.4 1 0 0 1 1 1 0 Presenilin SAGA-Tad1 PF12767.7 CDJ40101.1 - 0.022 14.5 4.7 0.033 13.9 4.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DDHD PF02862.17 CDJ40101.1 - 0.052 13.7 2.4 0.11 12.6 2.4 1.6 1 0 0 1 1 1 0 DDHD domain CSG2 PF16965.5 CDJ40101.1 - 0.12 11.3 0.3 0.2 10.6 0.3 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator SpoIIP PF07454.11 CDJ40101.1 - 0.17 11.3 3.3 0.28 10.6 3.3 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF648 PF04890.13 CDJ40101.1 - 0.31 10.7 2.8 0.44 10.3 2.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) PAT1 PF09770.9 CDJ40101.1 - 0.64 8.2 15.1 1.1 7.4 15.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4578 PF15147.6 CDJ40101.1 - 2.7 8.9 12.9 4.5 8.2 8.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) TERB2 PF15101.6 CDJ40101.1 - 9.9 6.1 10.3 1.1 9.2 4.5 2.0 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Spt20 PF12090.8 CDJ40102.1 - 5.1 6.6 9.8 5.9 6.4 2.5 2.1 2 0 0 2 2 2 0 Spt20 family Med3 PF11593.8 CDJ40103.1 - 0.11 11.6 4.5 0.12 11.5 4.5 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3275 PF11679.8 CDJ40104.1 - 2.2 8.2 6.9 2.5 8.0 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) HEAT_2 PF13646.6 CDJ40105.1 - 0.11 12.9 1.0 9.3 6.7 0.1 3.0 2 1 0 2 2 2 0 HEAT repeats TOM13 PF08219.11 CDJ40105.1 - 0.3 11.1 0.8 1.9 8.5 0.0 2.4 3 0 0 3 3 3 0 Outer membrane protein TOM13 DUF4148 PF13663.6 CDJ40107.1 - 0.47 10.7 10.7 2.6 8.3 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) FapA PF03961.13 CDJ40108.1 - 0.096 11.3 7.8 0.14 10.8 7.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF702 PF05142.12 CDJ40108.1 - 1.1 9.7 17.2 11 6.5 17.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF702) DDHD PF02862.17 CDJ40108.1 - 1.7 8.8 7.0 1 9.5 3.4 2.1 2 0 0 2 2 2 0 DDHD domain LMBR1 PF04791.16 CDJ40108.1 - 1.8 7.4 3.1 2.2 7.1 3.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Neur_chan_memb PF02932.16 CDJ40108.1 - 2.2 8.3 6.6 0.46 10.5 3.4 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF3573 PF12097.8 CDJ40108.1 - 2.2 7.0 8.0 3.7 6.3 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Presenilin PF01080.17 CDJ40108.1 - 6.5 5.4 10.0 12 4.6 10.0 1.3 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ40109.1 - 0.029 14.4 10.2 0.033 14.2 10.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V4R PF02830.18 CDJ40109.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 V4R domain UPF0239 PF06783.11 CDJ40111.1 - 0.0058 16.8 4.4 0.0058 16.8 4.4 6.3 5 1 1 6 6 6 1 Uncharacterised protein family (UPF0239) GTP_EFTU PF00009.27 CDJ40113.1 - 0.00069 19.2 0.0 0.00099 18.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CDJ40113.1 - 0.0012 18.9 1.2 0.0014 18.7 0.1 1.6 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CDJ40113.1 - 0.0042 17.2 0.1 0.0086 16.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SUIM_assoc PF16619.5 CDJ40113.1 - 0.067 13.3 6.1 0.11 12.6 6.1 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 FeoB_N PF02421.18 CDJ40113.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B Spt20 PF12090.8 CDJ40113.1 - 0.12 11.9 4.3 0.19 11.3 4.3 1.2 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ40113.1 - 0.13 11.2 1.3 0.18 10.7 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2722 PF10846.8 CDJ40114.1 - 0.0036 16.3 9.4 0.087 11.8 2.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Rad50_zn_hook PF04423.14 CDJ40114.1 - 0.055 13.3 1.3 0.11 12.3 1.3 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif Spt20 PF12090.8 CDJ40114.1 - 0.19 11.4 22.5 0.44 10.1 6.6 2.4 2 0 0 2 2 2 0 Spt20 family Peptidase_C12 PF01088.21 CDJ40115.1 - 0.017 14.8 0.1 0.018 14.8 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Med15 PF09606.10 CDJ40115.1 - 5.4 5.6 22.4 5.4 5.6 22.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ40115.1 - 9.6 6.1 17.4 11 5.9 17.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HemY_N PF07219.13 CDJ40116.1 - 0.22 11.7 0.1 0.22 11.7 0.1 4.3 4 2 1 5 5 5 0 HemY protein N-terminus BRF1 PF07741.13 CDJ40118.1 - 0.019 15.3 2.6 0.021 15.2 2.6 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Spt20 PF12090.8 CDJ40118.1 - 0.39 10.3 2.8 0.44 10.1 2.8 1.0 1 0 0 1 1 1 0 Spt20 family Herpes_capsid PF06112.11 CDJ40119.1 - 0.15 12.1 11.2 0.4 10.7 11.2 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein GLE1 PF07817.13 CDJ40120.1 - 6.6e-21 74.7 2.1 1.6e-20 73.4 2.1 1.7 1 1 0 1 1 1 1 GLE1-like protein Caldesmon PF02029.15 CDJ40120.1 - 0.00046 19.1 43.4 0.00065 18.6 43.4 1.1 1 0 0 1 1 1 1 Caldesmon DUF4778 PF16008.5 CDJ40120.1 - 0.14 12.2 23.3 0.24 11.4 23.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) V_ATPase_I PF01496.19 CDJ40120.1 - 3.1 5.6 25.3 5 4.9 25.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SR-25 PF10500.9 CDJ40120.1 - 6.1 6.4 55.6 1.1 8.8 17.5 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Hira PF07569.11 CDJ40121.1 - 0.027 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split SUIM_assoc PF16619.5 CDJ40121.1 - 0.028 14.5 1.4 0.095 12.8 1.4 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ40122.1 - 0.054 13.5 20.2 0.068 13.2 20.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt5_N PF11942.8 CDJ40123.1 - 0.035 15.1 5.3 0.052 14.5 5.3 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Sulfatase_C PF14707.6 CDJ40123.1 - 0.48 11.2 5.9 0.65 10.7 5.9 1.2 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF572 PF04502.13 CDJ40123.1 - 0.71 9.4 9.4 0.82 9.2 9.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIA PF03153.13 CDJ40123.1 - 1.3 9.0 26.0 1.4 8.8 26.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPT16 PF08644.11 CDJ40123.1 - 2.8 8.1 9.1 3.4 7.8 9.1 1.1 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Peptidase_S49_N PF08496.10 CDJ40123.1 - 3.9 7.5 9.6 5.1 7.1 9.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Exonuc_VII_L PF02601.15 CDJ40123.1 - 6.9 6.1 15.0 8.1 5.9 15.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit EIF4E-T PF10477.9 CDJ40125.1 - 4.2 6.1 17.6 0.19 10.5 12.0 1.5 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E PP2C PF00481.21 CDJ40126.1 - 9.7e-25 87.7 6.2 1e-18 67.9 0.2 2.8 3 1 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ40126.1 - 0.0023 17.6 6.3 0.0023 17.6 6.3 3.4 3 1 0 3 3 3 1 Protein phosphatase 2C Plasmodium_Vir PF05795.11 CDJ40127.1 - 0.55 9.6 5.6 0.91 8.9 3.2 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SUIM_assoc PF16619.5 CDJ40127.1 - 3.2 7.9 36.7 3 8.0 5.1 4.1 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 RAB3GAP2_N PF14655.6 CDJ40127.1 - 3.8 6.7 6.8 0.18 11.1 0.4 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.8 CDJ40127.1 - 6 6.4 26.6 0.09 12.4 8.0 2.9 3 0 0 3 3 3 0 Spt20 family YL1 PF05764.13 CDJ40129.1 - 0.31 11.1 20.7 0.4 10.7 20.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Pex14_N PF04695.13 CDJ40129.1 - 4.8 7.8 31.1 8.1 7.1 14.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SPX PF03105.19 CDJ40129.1 - 6.7 6.5 20.8 8 6.3 20.8 1.1 1 0 0 1 1 1 0 SPX domain MMR1 PF08505.10 CDJ40130.1 - 0.63 10.3 12.6 0.87 9.8 12.6 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF2868 PF11067.8 CDJ40130.1 - 1.1 8.8 17.4 1.4 8.4 17.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Mitofilin PF09731.9 CDJ40130.1 - 1.1 8.0 30.7 1.3 7.8 30.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Miga PF10265.9 CDJ40130.1 - 1.5 7.7 6.1 1.6 7.6 6.1 1.1 1 0 0 1 1 1 0 Mitoguardin DUF1180 PF06679.12 CDJ40130.1 - 2.3 8.6 34.1 0.25 11.7 12.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Neur_chan_memb PF02932.16 CDJ40130.1 - 3.4 7.7 7.7 4.1 7.4 7.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ40130.1 - 3.9 7.4 21.7 4.8 7.1 21.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 CDJ40130.1 - 4.1 6.1 9.1 4.9 5.8 9.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Conotoxin PF02950.17 CDJ40130.1 - 7.7 7.6 12.8 2.8e+02 2.6 12.8 3.0 1 1 0 1 1 1 0 Conotoxin DDHD PF02862.17 CDJ40130.1 - 8.1 6.5 9.8 12 6.0 9.8 1.3 1 0 0 1 1 1 0 DDHD domain CDC27 PF09507.10 CDJ40130.1 - 8.6 5.6 27.9 11 5.3 27.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.10 CDJ40130.1 - 9.4 4.8 15.5 12 4.4 15.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HIT PF01230.23 CDJ40131.1 - 3.3e-11 43.8 0.0 3.3e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 HIT domain COE1_HLH PF16423.5 CDJ40131.1 - 0.13 12.0 0.1 0.71 9.6 0.1 2.0 2 0 0 2 2 2 0 Transcription factor COE1 helix-loop-helix domain DPPIV_N PF00930.21 CDJ40132.1 - 2.4e-18 66.0 0.0 1.6e-13 50.2 0.0 3.2 3 0 0 3 3 3 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Ribosomal_60s PF00428.19 CDJ40132.1 - 0.0013 19.2 6.3 0.0013 19.2 6.3 4.1 3 1 1 4 4 4 1 60s Acidic ribosomal protein V_ATPase_I PF01496.19 CDJ40132.1 - 1.3 6.8 4.3 1.5 6.6 4.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIF_alpha PF05793.12 CDJ40132.1 - 1.6 7.2 17.5 2 6.9 3.5 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YABBY PF04690.13 CDJ40132.1 - 3.4 8.2 9.2 4.7 7.7 6.5 2.4 2 0 0 2 2 2 0 YABBY protein DUF4407 PF14362.6 CDJ40132.1 - 6.3 6.1 8.1 12 5.1 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CytochromB561_N PF09786.9 CDJ40134.1 - 1.7 7.5 15.7 1.8 7.5 15.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Suf PF05843.14 CDJ40134.1 - 2.5 8.0 9.5 2.8 7.8 9.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) QWRF PF04484.12 CDJ40134.1 - 4.3 7.0 15.7 4.9 6.8 15.7 1.1 1 0 0 1 1 1 0 QWRF family Pneumo_att_G PF05539.11 CDJ40134.1 - 5.6 6.5 15.0 6.4 6.3 15.0 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G CAML PF14963.6 CDJ40134.1 - 6.9 6.7 9.6 7.5 6.6 9.6 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand NST1 PF13945.6 CDJ40134.1 - 7.3 6.6 13.6 9.2 6.3 13.6 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator CCDC142 PF14923.6 CDJ40134.1 - 9 4.9 9.2 11 4.6 9.2 1.0 1 0 0 1 1 1 0 Coiled-coil protein 142 Kinesin PF00225.23 CDJ40136.1 - 2.2e-37 128.8 2.0 5.6e-25 88.0 0.1 2.0 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ40136.1 - 1.4e-16 60.8 0.0 1.8e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 CDJ40136.1 - 0.019 14.2 0.1 0.022 13.9 0.1 1.1 1 0 0 1 1 1 0 PIF1-like helicase AAA_30 PF13604.6 CDJ40136.1 - 0.1 12.3 0.2 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 AAA domain PP2C PF00481.21 CDJ40137.1 - 0.00047 19.9 0.0 0.00074 19.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3446 PF11928.8 CDJ40137.1 - 4.2 7.8 13.1 0.51 10.7 5.6 2.6 2 1 1 3 3 3 0 Early growth response N-terminal domain SR-25 PF10500.9 CDJ40137.1 - 7.8 6.0 7.3 12 5.4 7.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ40139.1 - 0.013 15.5 2.2 0.013 15.5 2.2 7.8 5 1 2 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 RAP1 PF07218.11 CDJ40139.1 - 0.37 9.0 2.0 0.47 8.7 2.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Birna_RdRp PF04197.12 CDJ40139.1 - 0.75 8.0 8.6 0.93 7.7 8.6 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) RRM_1 PF00076.22 CDJ40140.1 - 4.5e-17 61.6 0.0 2.5e-09 36.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ40140.1 - 0.0036 17.1 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif SUIM_assoc PF16619.5 CDJ40140.1 - 0.0049 16.9 15.5 0.021 14.8 2.1 2.7 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 DUF1744 PF08490.12 CDJ40140.1 - 0.16 10.5 0.0 0.33 9.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1744) Spt20 PF12090.8 CDJ40140.1 - 7.9 6.0 14.9 3.2 7.3 3.8 2.3 2 0 0 2 2 2 0 Spt20 family RIC1 PF07064.13 CDJ40142.1 - 0.0038 16.7 0.1 0.0074 15.7 0.1 1.4 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 CDJ40142.1 - 0.073 13.4 0.0 2.8 8.3 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RE_Bsp6I PF09504.10 CDJ40142.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Bsp6I restriction endonuclease TetR_C_14 PF17754.1 CDJ40143.1 - 1.1 9.2 8.9 0.29 11.1 0.1 3.3 3 0 0 3 3 3 0 MftR C-terminal domain RRM_1 PF00076.22 CDJ40144.1 - 3e-23 81.4 0.0 1.1e-07 31.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RuBisCO_large_N PF02788.16 CDJ40144.1 - 0.028 14.6 1.2 0.057 13.6 1.2 1.4 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain RRM_7 PF16367.5 CDJ40144.1 - 0.067 13.3 0.0 27 5.0 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif Tic110 PF16940.5 CDJ40144.1 - 8 4.8 6.5 13 4.1 6.5 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter MMR_HSR1 PF01926.23 CDJ40145.1 - 3.1e-17 62.7 0.1 3.3e-14 52.9 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase GN3L_Grn1 PF08701.11 CDJ40145.1 - 1.7e-10 40.9 8.8 1.7e-10 40.9 8.8 4.3 3 2 1 4 4 4 1 GNL3L/Grn1 putative GTPase FeoB_N PF02421.18 CDJ40145.1 - 4.8e-09 35.9 0.0 5.3e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDJ40145.1 - 6.2e-06 26.2 1.4 0.02 14.8 0.1 3.9 4 0 0 4 4 4 2 RsgA GTPase AAA_16 PF13191.6 CDJ40145.1 - 0.0063 16.9 0.0 0.0063 16.9 0.0 3.8 3 1 0 3 3 3 1 AAA ATPase domain GTP_EFTU PF00009.27 CDJ40145.1 - 0.0073 15.9 5.3 0.056 13.0 0.0 4.1 3 3 1 4 4 4 1 Elongation factor Tu GTP binding domain DUF687 PF05095.12 CDJ40145.1 - 0.21 10.0 2.0 0.33 9.4 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF687) Dynamin_N PF00350.23 CDJ40145.1 - 0.33 11.0 17.5 0.73 9.9 0.1 4.4 3 2 0 4 4 4 0 Dynamin family Utp21 PF04192.12 CDJ40145.1 - 8.3 5.8 12.8 1.1 8.7 6.6 2.2 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain PDZ_3 PF17815.1 CDJ40146.1 - 4e-41 140.3 0.2 8.6e-40 135.9 0.1 2.2 2 0 0 2 2 2 1 PDZ domain Trypsin_2 PF13365.6 CDJ40146.1 - 1.7e-08 35.5 2.7 0.00068 20.5 0.0 3.2 2 1 1 3 3 3 2 Trypsin-like peptidase domain Trypsin PF00089.26 CDJ40146.1 - 2.2e-06 27.6 2.4 0.0059 16.4 0.3 2.9 1 1 2 3 3 3 2 Trypsin PDZ_2 PF13180.6 CDJ40146.1 - 1.6e-05 25.1 0.2 0.00015 22.0 0.1 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CDJ40146.1 - 0.057 13.3 0.0 0.81 9.6 0.0 2.8 3 0 0 3 3 3 0 PDZ domain DUF1180 PF06679.12 CDJ40148.1 - 0.038 14.4 2.4 0.059 13.8 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF515 PF04415.12 CDJ40148.1 - 5 5.4 12.7 7.6 4.8 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF2870 PF11069.8 CDJ40149.1 - 5.2e-34 116.5 0.1 1.8e-33 114.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) ubiquitin PF00240.23 CDJ40149.1 - 3.1e-06 26.8 0.1 2.6 7.9 0.2 3.5 3 0 0 3 3 3 3 Ubiquitin family Type2_restr_D3 PF16902.5 CDJ40149.1 - 0.052 13.5 1.9 0.062 13.2 0.4 1.9 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain RTX PF02382.15 CDJ40150.1 - 0.035 13.8 0.2 0.035 13.8 0.2 2.5 3 0 0 3 3 3 0 N-terminal domain in RTX protein RNA_pol_Rpb4 PF03874.16 CDJ40151.1 - 2.2e-09 37.7 0.0 3.2e-09 37.2 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 UPF0147 PF03685.13 CDJ40153.1 - 0.16 12.1 1.3 0.43 10.7 1.3 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) T3SSipB PF16535.5 CDJ40153.1 - 6.7 7.2 10.3 12 6.3 0.8 3.0 3 0 0 3 3 3 0 Type III cell invasion protein SipB PHM7_cyt PF14703.6 CDJ40154.1 - 0.00018 21.8 1.0 0.12 12.6 0.8 2.1 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter DnaJ PF00226.31 CDJ40155.1 - 8.1e-08 32.3 0.0 2.2e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 CDJ40155.1 - 0.35 11.1 3.6 0.53 10.5 2.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ40155.1 - 0.76 9.7 5.5 0.57 10.1 1.8 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L6 PF00347.23 CDJ40156.1 - 4e-25 88.3 1.3 3.6e-14 53.2 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF4795 PF16043.5 CDJ40156.1 - 0.14 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF3090 PF11290.8 CDJ40157.1 - 0.056 13.3 0.3 0.083 12.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) VTC PF09359.10 CDJ40158.1 - 5e-88 295.1 0.0 7.1e-88 294.6 0.0 1.2 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 CDJ40158.1 - 6.5e-05 23.3 0.5 0.00023 21.5 0.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 CDJ40158.1 - 0.00096 19.2 0.4 0.00096 19.2 0.4 1.8 2 0 0 2 2 2 1 SPX domain Thioredoxin PF00085.20 CDJ40159.1 - 0.018 15.0 0.0 0.048 13.6 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 CDJ40159.1 - 0.18 12.3 0.0 0.5 10.8 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain AAA PF00004.29 CDJ40160.1 - 8.4e-94 311.0 0.0 1.5e-46 158.1 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ40160.1 - 5e-24 83.8 13.1 1.3e-13 50.5 0.6 3.5 3 1 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 CDJ40160.1 - 2.2e-21 75.8 0.8 5.1e-21 74.7 0.8 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CDJ40160.1 - 1.1e-13 51.2 0.0 5e-06 26.3 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ40160.1 - 1.5e-12 48.2 0.4 0.00054 20.4 0.1 4.2 2 2 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 CDJ40160.1 - 2.6e-11 43.9 0.0 2.1e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CDJ40160.1 - 1.5e-10 41.4 0.0 5.5e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CDJ40160.1 - 2.1e-10 40.7 0.1 3.7e-05 23.8 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 CDJ40160.1 - 1.4e-09 37.6 0.0 3.4e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 CDJ40160.1 - 5.5e-09 36.4 0.2 0.073 13.3 0.0 3.9 2 2 2 4 4 3 2 AAA domain TIP49 PF06068.13 CDJ40160.1 - 1.6e-08 34.2 0.0 0.00076 18.8 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 CDJ40160.1 - 1.2e-07 31.8 0.0 0.0018 18.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CDJ40160.1 - 2.8e-07 31.2 0.0 0.03 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CDJ40160.1 - 5.6e-07 29.2 0.3 0.038 13.4 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDJ40160.1 - 8.6e-07 29.3 0.0 0.019 15.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Vps4_C PF09336.10 CDJ40160.1 - 1.1e-06 28.5 0.1 0.0007 19.5 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 CDJ40160.1 - 1.2e-06 28.2 1.0 0.81 9.2 0.0 3.9 3 1 0 4 4 4 2 AAA domain IstB_IS21 PF01695.17 CDJ40160.1 - 1.3e-05 25.0 0.0 0.18 11.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 CDJ40160.1 - 3.6e-05 23.8 0.1 0.65 9.9 0.1 3.2 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_28 PF13521.6 CDJ40160.1 - 3.9e-05 23.9 0.0 0.46 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CDJ40160.1 - 4.6e-05 23.0 0.0 0.35 10.3 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 CDJ40160.1 - 4.9e-05 23.3 0.1 0.53 10.2 0.0 3.4 2 1 0 3 3 3 2 NACHT domain ATPase PF06745.13 CDJ40160.1 - 5.3e-05 22.7 0.1 2.5 7.4 0.0 3.3 3 0 0 3 3 3 1 KaiC ABC_tran PF00005.27 CDJ40160.1 - 5.3e-05 23.7 0.0 0.29 11.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_17 PF13207.6 CDJ40160.1 - 5.7e-05 23.6 0.0 0.18 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CDJ40160.1 - 0.0001 22.1 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CDJ40160.1 - 0.00016 21.5 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 CDJ40160.1 - 0.00017 21.6 0.0 0.93 9.5 0.0 2.8 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 CDJ40160.1 - 0.00022 20.4 0.0 0.55 9.3 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 CDJ40160.1 - 0.00038 19.7 0.0 0.87 8.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.26 CDJ40160.1 - 0.00057 19.6 0.0 1.4 8.6 0.0 3.4 2 2 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 CDJ40160.1 - 0.0008 18.7 0.0 0.81 8.9 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 CDJ40160.1 - 0.0011 18.2 0.0 0.4 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 CDJ40160.1 - 0.0012 19.0 0.0 0.61 10.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Bac_DnaA PF00308.18 CDJ40160.1 - 0.002 18.0 0.0 0.88 9.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein Rad17 PF03215.15 CDJ40160.1 - 0.0022 17.9 0.0 0.91 9.4 0.0 2.8 2 1 1 3 3 2 1 Rad17 P-loop domain PhoH PF02562.16 CDJ40160.1 - 0.0026 17.2 0.2 1.9 7.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.11 CDJ40160.1 - 0.0027 17.6 0.0 3.1 7.7 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 CDJ40160.1 - 0.0055 16.9 0.1 2.4 8.3 0.0 2.9 3 0 0 3 3 3 1 Cytidylate kinase-like family ResIII PF04851.15 CDJ40160.1 - 0.0066 16.5 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CDJ40160.1 - 0.0088 15.3 0.0 0.89 8.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 CDJ40160.1 - 0.017 15.0 1.1 13 5.7 0.0 3.8 4 0 0 4 4 3 0 NTPase AAA_19 PF13245.6 CDJ40160.1 - 0.02 15.2 1.2 6.9 7.0 0.1 3.3 3 1 1 4 4 2 0 AAA domain KAP_NTPase PF07693.14 CDJ40160.1 - 0.024 13.9 0.1 3.4 6.8 0.0 3.3 2 2 2 4 4 4 0 KAP family P-loop domain AAA_30 PF13604.6 CDJ40160.1 - 0.025 14.3 0.1 6.5 6.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 CDJ40160.1 - 0.035 14.2 0.1 18 5.4 0.0 3.0 3 0 0 3 3 3 0 Shikimate kinase AAA_11 PF13086.6 CDJ40160.1 - 0.05 13.4 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 CDJ40160.1 - 0.065 13.0 0.1 8.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase UFD1 PF03152.14 CDJ40160.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 TniB PF05621.11 CDJ40160.1 - 0.18 11.2 0.1 14 5.1 0.0 3.2 4 0 0 4 4 3 0 Bacterial TniB protein AAA_29 PF13555.6 CDJ40160.1 - 0.23 11.2 2.5 6.1 6.7 0.0 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain Hydin_ADK PF17213.3 CDJ40160.1 - 6 7.1 6.7 63 3.8 0.0 4.3 5 0 0 5 5 5 0 Hydin Adenylate kinase-like domain HIT PF01230.23 CDJ40161.1 - 5.1e-22 78.4 0.1 6.8e-22 78.0 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CDJ40161.1 - 4.8e-10 39.9 0.0 5.7e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Orexin PF02072.15 CDJ40161.1 - 0.027 14.4 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Prepro-orexin Pkinase PF00069.25 CDJ40162.1 - 4.4e-40 137.7 0.0 4.3e-13 49.2 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ40162.1 - 4.3e-21 75.4 0.0 4e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ40162.1 - 4.6e-06 25.8 0.0 0.019 14.5 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CDJ40162.1 - 6.5e-05 23.3 0.0 1.7 9.2 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ40162.1 - 0.00096 18.9 0.3 2.4 8.3 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDJ40162.1 - 0.041 13.7 0.1 1.4 8.8 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 CDJ40162.1 - 0.096 12.2 0.2 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 EF hand BSP_II PF05432.11 CDJ40162.1 - 0.72 9.5 2.5 1.7 8.3 2.5 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) M16C_assoc PF08367.11 CDJ40162.1 - 2.8 7.0 5.6 73 2.4 0.0 2.4 2 0 0 2 2 2 0 Peptidase M16C associated SUIM_assoc PF16619.5 CDJ40163.1 - 0.0061 16.6 29.0 0.35 11.0 3.7 4.5 3 1 0 3 3 3 3 Unstructured region C-term to UIM in Ataxin3 DUF3253 PF11625.8 CDJ40163.1 - 0.12 12.7 0.2 0.12 12.7 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3253) NPR3 PF03666.13 CDJ40164.1 - 0.00093 18.1 8.7 0.0022 16.9 8.7 1.5 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 CDJ40164.1 - 0.0021 16.4 15.0 0.0029 15.9 15.0 1.1 1 0 0 1 1 1 1 Nop14-like family Peroxin-3 PF04882.12 CDJ40164.1 - 0.012 14.7 8.8 6.8 5.6 12.9 2.3 2 1 0 2 2 2 0 Peroxin-3 Pox_Ag35 PF03286.14 CDJ40164.1 - 0.018 14.8 10.2 0.035 13.9 10.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RR_TM4-6 PF06459.12 CDJ40164.1 - 0.063 13.1 18.8 0.14 12.0 18.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SMN PF06003.12 CDJ40164.1 - 0.069 12.4 4.4 0.16 11.2 4.4 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) PAT1 PF09770.9 CDJ40164.1 - 0.069 11.4 15.6 0.097 10.9 15.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF913 PF06025.12 CDJ40164.1 - 0.12 11.3 7.6 0.32 9.9 7.6 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Merozoite_SPAM PF07133.11 CDJ40164.1 - 0.23 11.4 25.8 0.37 10.8 25.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) V_ATPase_I PF01496.19 CDJ40164.1 - 0.3 9.0 15.5 0.41 8.5 15.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SAPS PF04499.15 CDJ40164.1 - 0.3 9.8 10.1 0.45 9.2 10.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 CDJ40164.1 - 0.35 8.9 11.0 0.51 8.4 11.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EBP50_C PF09007.11 CDJ40164.1 - 0.47 11.4 16.4 2.2 9.3 8.3 3.1 3 0 0 3 3 3 0 EBP50, C-terminal Raftlin PF15250.6 CDJ40164.1 - 0.48 9.1 10.7 0.038 12.8 5.9 1.5 2 0 0 2 2 2 0 Raftlin Endostatin PF06482.11 CDJ40164.1 - 0.55 9.6 8.6 0.95 8.9 8.6 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin TRAP_alpha PF03896.16 CDJ40164.1 - 0.59 9.3 9.8 1.2 8.3 9.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 CDJ40164.1 - 0.69 8.1 18.7 1.3 7.2 18.7 1.4 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 CDJ40164.1 - 0.86 9.0 15.1 1.8 7.9 15.1 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Vfa1 PF08432.10 CDJ40164.1 - 0.87 9.9 17.9 1.7 9.0 17.9 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Drc1-Sld2 PF11719.8 CDJ40164.1 - 0.88 9.1 16.3 1.5 8.3 16.3 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF2828 PF11443.8 CDJ40164.1 - 1.1 7.3 12.2 1.5 6.8 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PIP5K PF01504.18 CDJ40164.1 - 1.2 8.4 8.3 2.2 7.5 8.3 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase BORG_CEP PF14957.6 CDJ40164.1 - 1.6 9.9 17.1 1.5 10.0 9.0 3.0 3 0 0 3 3 3 0 Cdc42 effector Neur_chan_memb PF02932.16 CDJ40164.1 - 1.7 8.6 10.0 4.1 7.4 10.0 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.12 CDJ40164.1 - 2.3 7.5 14.5 4.7 6.5 14.5 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Suf PF05843.14 CDJ40164.1 - 2.4 8.1 11.4 5 7.0 11.4 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AUX_IAA PF02309.16 CDJ40164.1 - 2.5 7.9 7.8 6.7 6.5 7.8 1.7 1 0 0 1 1 1 0 AUX/IAA family ALMT PF11744.8 CDJ40164.1 - 2.6 6.8 11.3 3.9 6.2 11.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DNA_pol_phi PF04931.13 CDJ40164.1 - 2.7 6.0 18.8 3.9 5.5 18.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi SpoIIIAH PF12685.7 CDJ40164.1 - 3 7.6 20.8 0.38 10.5 12.9 2.6 3 0 0 3 3 2 0 SpoIIIAH-like protein Spore_coat_CotO PF14153.6 CDJ40164.1 - 3.1 7.7 25.2 0.35 10.8 19.2 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Membralin PF09746.9 CDJ40164.1 - 3.2 6.7 5.5 4.6 6.2 5.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein Band_3_cyto PF07565.13 CDJ40164.1 - 3.2 7.5 13.6 5.8 6.6 13.6 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SID-1_RNA_chan PF13965.6 CDJ40164.1 - 3.3 6.0 3.9 4.6 5.5 3.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Connexin PF00029.19 CDJ40164.1 - 4.5 7.0 11.3 9.7 5.9 11.3 1.5 1 0 0 1 1 1 0 Connexin Smg8_Smg9 PF10220.9 CDJ40164.1 - 4.8 5.4 14.8 8.5 4.5 14.8 1.3 1 0 0 1 1 1 0 Smg8_Smg9 GREB1 PF15782.5 CDJ40164.1 - 5.4 4.0 11.1 0.099 9.8 3.4 1.9 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 CDJ40164.1 - 6 5.5 25.0 0.26 10.0 19.0 1.7 2 0 0 2 2 2 0 Presenilin CLN3 PF02487.17 CDJ40164.1 - 6.5 5.7 10.6 10 5.1 10.6 1.2 1 0 0 1 1 1 0 CLN3 protein AAA_11 PF13086.6 CDJ40164.1 - 6.7 6.4 15.8 12 5.6 15.8 1.3 1 0 0 1 1 1 0 AAA domain DUF3362 PF11842.8 CDJ40164.1 - 6.9 7.0 25.0 0.041 14.2 15.3 2.1 2 1 0 2 2 1 0 Domain of unknown function (DUF3362) SLC12 PF03522.15 CDJ40164.1 - 7.5 5.4 16.8 12 4.8 16.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RPN2_C PF18004.1 CDJ40164.1 - 8.3 6.3 16.9 16 5.4 16.9 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CSG2 PF16965.5 CDJ40164.1 - 9.4 5.1 6.5 15 4.4 6.5 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DUF374 PF04028.13 CDJ40165.1 - 0.027 14.0 0.9 0.062 12.9 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Utp14 PF04615.13 CDJ40165.1 - 3.1 6.2 22.4 3.7 6.0 22.4 1.0 1 0 0 1 1 1 0 Utp14 protein TFIIA PF03153.13 CDJ40166.1 - 0.78 9.7 13.6 0.93 9.4 13.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NPL4 PF05021.15 CDJ40167.1 - 7.1e-09 35.5 0.0 6.7e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 NPL4 family TPR_2 PF07719.17 CDJ40168.1 - 0.00053 19.9 14.0 0.49 10.6 2.5 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat SR-25 PF10500.9 CDJ40168.1 - 0.0011 18.7 21.3 0.012 15.3 3.0 4.3 4 0 0 4 4 4 3 Nuclear RNA-splicing-associated protein TPR_1 PF00515.28 CDJ40168.1 - 1.6 8.7 9.6 21 5.1 0.8 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PBP1_TM PF14812.6 CDJ40168.1 - 2.7 8.4 5.6 12 6.3 0.0 3.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_8 PF13181.6 CDJ40168.1 - 3 8.3 5.6 15 6.1 0.5 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat SID-1_RNA_chan PF13965.6 CDJ40168.1 - 8 4.7 6.6 1.7 7.0 2.6 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 ELMO_CED12 PF04727.13 CDJ40169.1 - 1.2e-25 90.6 0.6 1.2e-25 90.6 0.6 3.2 3 1 0 3 3 3 1 ELMO/CED-12 family ARTD15_N PF18084.1 CDJ40169.1 - 0.018 15.3 0.4 0.11 12.8 0.4 2.4 1 0 0 1 1 1 0 ARTD15 N-terminal domain RskA PF10099.9 CDJ40169.1 - 0.05 13.9 0.0 0.05 13.9 0.0 11.5 3 2 4 10 10 10 0 Anti-sigma-K factor rskA Hamartin PF04388.12 CDJ40170.1 - 0.0062 15.3 31.6 0.0082 14.9 31.6 1.1 1 0 0 1 1 1 1 Hamartin protein DUF1943 PF09172.11 CDJ40170.1 - 0.85 8.8 9.8 1.7 7.8 9.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) MMR1 PF08505.10 CDJ40170.1 - 1.2 9.3 30.3 0.62 10.3 23.8 2.6 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein SpoIIP PF07454.11 CDJ40170.1 - 2.2 7.7 20.3 0.38 10.2 14.9 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF913 PF06025.12 CDJ40170.1 - 3.2 6.6 15.5 28 3.5 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF572 PF04502.13 CDJ40170.1 - 3.8 7.0 27.7 0.63 9.6 22.6 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) Presenilin PF01080.17 CDJ40170.1 - 6.4 5.4 30.1 0.63 8.7 22.6 2.2 2 0 0 2 2 2 0 Presenilin RR_TM4-6 PF06459.12 CDJ40170.1 - 9.8 5.9 28.7 1.6 8.5 23.6 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF1152 PF06626.12 CDJ40171.1 - 0.049 12.8 1.2 0.13 11.5 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) NOG1_N PF17835.1 CDJ40172.1 - 9.5e-32 110.2 0.6 9.5e-32 110.2 0.6 3.3 2 1 0 3 3 3 1 NOG1 N-terminal helical domain NOGCT PF08155.11 CDJ40172.1 - 2.2e-23 82.0 3.5 2.2e-23 82.0 3.5 2.2 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.14 CDJ40172.1 - 1.1e-22 79.5 0.7 3.5e-22 77.9 0.7 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 CDJ40172.1 - 8.2e-18 64.6 0.0 2.7e-17 62.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ40172.1 - 3.4e-12 46.1 0.0 5.7e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RskA PF10099.9 CDJ40172.1 - 3.3e-05 24.2 0.4 0.00011 22.6 0.3 1.9 2 1 0 2 2 2 1 Anti-sigma-K factor rskA Sec34 PF04136.15 CDJ40172.1 - 0.0046 16.8 0.1 0.0046 16.8 0.1 3.0 3 0 0 3 3 3 1 Sec34-like family RsgA_GTPase PF03193.16 CDJ40172.1 - 0.0063 16.4 5.6 0.039 13.8 0.0 3.2 3 1 0 3 3 3 1 RsgA GTPase SRPRB PF09439.10 CDJ40172.1 - 0.0081 15.6 0.2 0.0081 15.6 0.2 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CDJ40172.1 - 0.026 14.0 0.4 0.026 14.0 0.4 3.1 4 0 0 4 4 4 0 ADP-ribosylation factor family AAA_16 PF13191.6 CDJ40172.1 - 0.03 14.7 0.2 0.03 14.7 0.2 3.9 2 2 1 3 3 3 0 AAA ATPase domain Presenilin PF01080.17 CDJ40173.1 - 0.00012 21.0 38.9 0.00013 20.9 38.9 1.1 1 0 0 1 1 1 1 Presenilin CCSAP PF15748.5 CDJ40173.1 - 0.00022 21.5 35.4 0.00028 21.2 35.4 1.3 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated DUF4045 PF13254.6 CDJ40173.1 - 0.0021 17.8 28.8 0.0024 17.6 28.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) PAT1 PF09770.9 CDJ40173.1 - 0.0046 15.3 61.9 0.0052 15.1 61.9 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 CDJ40173.1 - 0.0065 14.8 30.1 0.0077 14.6 30.1 1.0 1 0 0 1 1 1 1 CDC45-like protein Lin-8 PF03353.15 CDJ40173.1 - 0.0073 15.9 37.7 0.0085 15.7 37.7 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist DUF1387 PF07139.11 CDJ40173.1 - 0.013 15.2 29.6 0.02 14.6 29.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF572 PF04502.13 CDJ40173.1 - 0.014 15.1 29.1 0.016 14.8 29.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SLC12 PF03522.15 CDJ40173.1 - 0.019 14.0 36.9 0.021 13.8 36.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 CDJ40173.1 - 0.019 13.8 31.5 0.02 13.7 31.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 CDJ40173.1 - 0.024 13.5 21.2 0.026 13.4 21.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ40173.1 - 0.025 13.2 22.5 0.028 13.0 22.5 1.1 1 0 0 1 1 1 0 Macoilin family LTV PF04180.14 CDJ40173.1 - 0.034 13.9 27.0 0.054 13.2 27.0 1.4 1 0 0 1 1 1 0 Low temperature viability protein Caldesmon PF02029.15 CDJ40173.1 - 0.041 12.6 34.6 0.044 12.6 34.6 1.1 1 0 0 1 1 1 0 Caldesmon AAA_11 PF13086.6 CDJ40173.1 - 0.043 13.6 31.9 0.055 13.2 31.9 1.1 1 0 0 1 1 1 0 AAA domain AbLIM_anchor PF16182.5 CDJ40173.1 - 0.044 13.6 19.9 0.065 13.1 19.9 1.3 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM DUF966 PF06136.13 CDJ40173.1 - 0.055 13.2 24.8 0.064 13.0 24.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Raftlin PF15250.6 CDJ40173.1 - 0.081 11.7 28.5 0.089 11.5 28.5 1.1 1 0 0 1 1 1 0 Raftlin Dapper PF15268.6 CDJ40173.1 - 0.094 11.6 39.5 0.1 11.4 39.5 1.0 1 0 0 1 1 1 0 Dapper Exonuc_VII_L PF02601.15 CDJ40173.1 - 0.16 11.5 38.3 0.18 11.4 38.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AF-4 PF05110.13 CDJ40173.1 - 0.17 10.0 40.4 0.19 9.8 40.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein WTX PF09422.10 CDJ40173.1 - 0.17 10.9 23.6 0.2 10.7 23.6 1.2 1 0 0 1 1 1 0 WTX protein Hamartin PF04388.12 CDJ40173.1 - 0.19 10.4 32.2 0.2 10.3 32.2 1.1 1 0 0 1 1 1 0 Hamartin protein FAM60A PF15396.6 CDJ40173.1 - 0.21 11.6 32.0 0.31 11.0 32.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Membralin PF09746.9 CDJ40173.1 - 0.25 10.3 21.6 0.31 10.0 21.6 1.2 1 0 0 1 1 1 0 Tumour-associated protein GREB1 PF15782.5 CDJ40173.1 - 0.26 8.4 39.0 0.3 8.2 39.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RR_TM4-6 PF06459.12 CDJ40173.1 - 0.3 10.9 40.1 0.44 10.3 40.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ40173.1 - 0.46 9.3 29.1 0.57 8.9 29.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SAGA-Tad1 PF12767.7 CDJ40173.1 - 0.57 9.9 32.9 0.69 9.6 32.9 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Hid1 PF12722.7 CDJ40173.1 - 0.59 8.2 37.8 0.81 7.7 37.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Smg8_Smg9 PF10220.9 CDJ40173.1 - 0.69 8.2 34.7 0.8 7.9 34.7 1.0 1 0 0 1 1 1 0 Smg8_Smg9 LAP1C PF05609.12 CDJ40173.1 - 0.88 8.6 37.5 1 8.4 37.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) LicD PF04991.13 CDJ40173.1 - 1.1 9.4 12.3 1.3 9.1 12.3 1.2 1 0 0 1 1 1 0 LicD family DUF2151 PF10221.9 CDJ40173.1 - 1.2 7.7 21.8 1.3 7.5 21.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator PA26 PF04636.13 CDJ40173.1 - 1.2 8.0 28.2 1.5 7.7 28.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Rtf2 PF04641.12 CDJ40173.1 - 1.5 8.2 32.5 2.6 7.3 32.5 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger MDM10 PF12519.8 CDJ40173.1 - 2.1 7.1 33.3 2.6 6.8 33.3 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Zip PF02535.22 CDJ40173.1 - 3.3 6.8 22.2 4.3 6.4 22.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 CDJ40173.1 - 3.4 6.3 30.9 4.2 6.0 30.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4569 PF15133.6 CDJ40173.1 - 5.2 6.7 38.9 8.3 6.0 38.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Ndc1_Nup PF09531.10 CDJ40173.1 - 7.5 5.1 39.0 8.7 4.9 39.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2052 PF09747.9 CDJ40173.1 - 9.5 6.3 40.5 15 5.7 40.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) GDA1_CD39 PF01150.17 CDJ40174.1 - 2.9e-26 92.1 4.9 1.4e-23 83.3 0.0 4.3 2 1 0 2 2 1 1 GDA1/CD39 (nucleoside phosphatase) family Collagen PF01391.18 CDJ40174.1 - 2.1e-05 24.2 38.7 2.1e-05 24.2 38.7 3.3 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Peroxin-3 PF04882.12 CDJ40174.1 - 0.00027 20.1 14.7 0.0068 15.4 3.7 2.2 2 0 0 2 2 2 2 Peroxin-3 SPX PF03105.19 CDJ40174.1 - 0.00064 19.8 16.3 0.0017 18.4 1.3 2.3 2 0 0 2 2 2 2 SPX domain Neur_chan_memb PF02932.16 CDJ40174.1 - 0.0014 18.7 0.8 0.0014 18.7 0.8 2.6 2 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF4667 PF15700.5 CDJ40174.1 - 0.0022 18.1 3.9 0.0022 18.1 3.9 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) Velvet PF11754.8 CDJ40174.1 - 0.0073 16.3 20.1 0.17 11.8 0.1 2.4 2 0 0 2 2 2 2 Velvet factor Lin-8 PF03353.15 CDJ40174.1 - 0.045 13.3 28.2 0.058 12.9 0.7 2.4 2 1 0 2 2 2 0 Ras-mediated vulval-induction antagonist SpoIIIAH PF12685.7 CDJ40174.1 - 0.78 9.5 31.0 3.3 7.5 2.6 3.1 3 0 0 3 3 3 0 SpoIIIAH-like protein DUF5308 PF17233.2 CDJ40174.1 - 0.84 9.8 26.3 1.7 8.8 2.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5308) MRP-S26 PF14943.6 CDJ40174.1 - 1.1 9.2 31.1 0.078 12.9 21.4 2.3 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 CPSF100_C PF13299.6 CDJ40174.1 - 1.3 9.2 23.0 15 5.7 14.2 3.3 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal SAPS PF04499.15 CDJ40174.1 - 1.8 7.3 18.5 4.2 6.0 0.4 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 CDJ40174.1 - 2.9 6.8 20.7 3.4 6.6 0.1 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Plasmodium_Vir PF05795.11 CDJ40174.1 - 2.9 7.2 16.2 1.8 7.9 0.8 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF4106 PF13388.6 CDJ40174.1 - 3.8 6.6 22.3 6.9 5.8 22.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RNA_pol_Rpc4 PF05132.14 CDJ40174.1 - 4.7 7.6 26.9 0.77 10.2 11.0 3.3 3 0 0 3 3 3 0 RNA polymerase III RPC4 AUX_IAA PF02309.16 CDJ40174.1 - 5.9 6.7 15.9 8.2 6.2 9.3 2.8 3 0 0 3 3 3 0 AUX/IAA family EOS1 PF12326.8 CDJ40174.1 - 6.2 6.7 16.5 34 4.3 0.0 3.0 3 0 0 3 3 3 0 N-glycosylation protein SARAF PF06682.12 CDJ40174.1 - 7.6 6.1 26.7 0.4 10.3 3.1 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Apt1 PF10351.9 CDJ40174.1 - 9.8 4.9 33.4 0.23 10.3 7.9 2.5 3 0 0 3 3 3 0 Golgi-body localisation protein domain SR-25 PF10500.9 CDJ40175.1 - 0.0026 17.4 13.4 0.0026 17.4 13.4 4.6 4 1 0 4 4 4 1 Nuclear RNA-splicing-associated protein Ferlin_C PF16165.5 CDJ40175.1 - 9.2 6.2 6.1 5.3 7.0 4.1 1.7 2 0 0 2 2 2 0 Ferlin C-terminus CDC45 PF02724.14 CDJ40175.1 - 9.9 4.3 11.0 20 3.3 7.7 2.0 2 0 0 2 2 2 0 CDC45-like protein Phasin_2 PF09361.10 CDJ40176.1 - 1.4 9.2 11.3 0.28 11.5 7.2 1.9 2 0 0 2 2 2 0 Phasin protein ODR4-like PF14778.6 CDJ40177.1 - 0.092 11.7 0.8 0.14 11.1 0.8 1.2 1 0 0 1 1 1 0 Olfactory receptor 4-like PT PF04886.12 CDJ40177.1 - 0.39 10.3 14.3 0.16 11.6 11.1 2.0 2 0 0 2 2 2 0 PT repeat Integrase_DNA PF02920.15 CDJ40177.1 - 0.94 9.2 3.0 2 8.2 3.0 1.5 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase CCDC53 PF10152.9 CDJ40178.1 - 0.74 10.2 2.9 0.95 9.9 2.9 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex MSA-2c PF12238.8 CDJ40178.1 - 2 8.4 4.4 2.4 8.1 4.4 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Chorion_2 PF03964.15 CDJ40178.1 - 6.3 7.7 8.4 12 6.8 8.3 1.5 1 1 0 1 1 1 0 Chorion family 2 Peptidase_M17 PF00883.21 CDJ40179.1 - 1e-115 386.3 0.1 1.4e-115 385.8 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 CDJ40179.1 - 9.5e-13 48.1 1.0 8.1e-12 45.1 0.1 2.5 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain Bot1p PF12298.8 CDJ40181.1 - 0.036 14.2 1.5 0.98 9.6 0.6 2.5 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein DUF2935 PF11155.8 CDJ40181.1 - 0.62 10.4 3.1 0.98 9.8 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Shadoo PF14999.6 CDJ40181.1 - 4.4 7.4 7.9 4.3 7.4 5.3 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Mucin PF01456.17 CDJ40182.1 - 0.012 15.6 35.4 0.024 14.6 12.9 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein RabGAP-TBC PF00566.18 CDJ40183.1 - 4.3e-33 114.8 1.2 8.4e-18 64.8 0.1 3.2 2 1 0 2 2 2 2 Rab-GTPase-TBC domain SlyX PF04102.12 CDJ40183.1 - 0.0012 19.4 3.8 0.17 12.5 1.3 3.0 2 0 0 2 2 2 2 SlyX Peptidase_C48 PF02902.19 CDJ40184.1 - 0.00065 19.6 0.0 0.011 15.6 0.0 2.4 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1412 PF07203.11 CDJ40185.1 - 0.13 12.5 0.1 0.34 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1412) DUF1640 PF07798.11 CDJ40188.1 - 0.21 11.6 1.3 0.31 11.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Borrelia_P83 PF05262.11 CDJ40188.1 - 1.7 7.0 6.7 2.2 6.7 6.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein POX PF07526.11 CDJ40188.1 - 7.9 7.1 7.2 12 6.5 7.2 1.2 1 0 0 1 1 1 0 Associated with HOX SR-25 PF10500.9 CDJ40189.1 - 0.0025 17.4 4.3 0.0025 17.4 4.3 3.5 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein Flavokinase PF01687.17 CDJ40192.1 - 6.5e-23 81.2 0.0 1.2e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase UPF0240 PF06784.11 CDJ40192.1 - 0.24 11.5 1.6 0.65 10.0 1.6 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) SPX PF03105.19 CDJ40192.1 - 1.3 8.8 6.5 0.33 10.8 1.1 2.1 2 0 0 2 2 2 0 SPX domain SR-25 PF10500.9 CDJ40192.1 - 2.1 7.9 9.3 7.2 6.1 9.3 1.9 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RIB43A PF05914.12 CDJ40193.1 - 0.00041 19.2 10.2 0.00041 19.2 10.2 2.5 2 1 0 2 2 2 1 RIB43A RskA PF10099.9 CDJ40193.1 - 0.49 10.7 22.8 1.7 8.9 22.8 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA ANAPC1 PF12859.7 CDJ40193.1 - 2.8 8.5 10.5 7.9 7.1 7.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Mitoc_L55 PF09776.9 CDJ40193.1 - 4.5 7.1 6.6 5.4 6.8 0.0 3.0 2 1 2 4 4 4 0 Mitochondrial ribosomal protein L55 RIFIN PF02009.16 CDJ40193.1 - 5.4 6.8 19.6 2.9 7.7 17.8 1.5 1 1 0 1 1 1 0 Rifin SR-25 PF10500.9 CDJ40193.1 - 7.3 6.1 55.2 0.19 11.3 6.5 3.1 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein PRIMA1 PF16101.5 CDJ40195.1 - 0.6 10.2 5.8 1 9.4 5.8 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 APH PF01636.23 CDJ40195.1 - 6.4 6.6 9.6 8.9 6.2 9.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Cytochrom_B562 PF07361.11 CDJ40195.1 - 9 7.0 6.6 4.7 7.9 1.2 2.6 3 0 0 3 3 3 0 Cytochrome b562 Macoilin PF09726.9 CDJ40196.1 - 0.02 13.5 15.7 0.027 13.0 15.7 1.2 1 0 0 1 1 1 0 Macoilin family DUF1115 PF06544.12 CDJ40196.1 - 0.038 14.1 3.2 0.065 13.3 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) Spt20 PF12090.8 CDJ40196.1 - 0.056 13.0 21.7 0.095 12.3 21.7 1.4 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ40196.1 - 0.17 10.8 30.6 0.044 12.8 27.0 1.7 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Zip PF02535.22 CDJ40196.1 - 0.26 10.5 2.5 0.31 10.2 2.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SPX PF03105.19 CDJ40196.1 - 0.27 11.1 14.1 0.34 10.8 14.1 1.2 1 0 0 1 1 1 0 SPX domain Lin-8 PF03353.15 CDJ40196.1 - 0.37 10.3 11.2 0.56 9.7 11.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SelP_N PF04592.14 CDJ40196.1 - 0.63 9.4 12.7 1 8.7 12.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PAT1 PF09770.9 CDJ40196.1 - 0.8 7.9 17.8 0.91 7.7 17.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EIIBC-GUT_N PF03612.14 CDJ40196.1 - 0.81 9.4 4.5 1.4 8.6 4.5 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus THOC2_N PF16134.5 CDJ40196.1 - 0.93 8.0 8.5 0.85 8.2 4.9 1.9 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus WDCP PF15390.6 CDJ40196.1 - 2.2 6.6 14.0 2.9 6.1 14.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family GREB1 PF15782.5 CDJ40196.1 - 2.7 5.0 17.2 2.9 4.9 17.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer VIT1 PF01988.19 CDJ40196.1 - 2.9 7.7 8.1 1.2 9.0 4.2 2.1 2 0 0 2 2 2 0 VIT family DUF3464 PF11947.8 CDJ40196.1 - 3 7.6 6.9 6.9 6.4 6.9 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TFIIA PF03153.13 CDJ40196.1 - 3.8 7.4 34.5 4.1 7.3 33.9 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Plasmodium_Vir PF05795.11 CDJ40196.1 - 3.8 6.8 7.8 5.1 6.4 7.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Connexin PF00029.19 CDJ40196.1 - 4.1 7.1 6.3 6.3 6.5 6.3 1.2 1 0 0 1 1 1 0 Connexin eIF-3_zeta PF05091.12 CDJ40196.1 - 5.3 5.9 12.7 7 5.5 12.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Roughex PF06020.11 CDJ40196.1 - 5.5 6.0 8.7 7.7 5.5 8.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Stig1 PF04885.13 CDJ40196.1 - 6.7 7.2 9.1 16 6.0 9.1 1.6 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 RR_TM4-6 PF06459.12 CDJ40196.1 - 8.3 6.1 13.9 13 5.5 13.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MutL PF13941.6 CDJ40197.1 - 0.08 11.5 1.6 0.094 11.3 1.6 1.1 1 0 0 1 1 1 0 MutL protein Activator_LAG-3 PF11498.8 CDJ40197.1 - 0.11 11.5 32.8 0.16 10.9 32.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RskA PF10099.9 CDJ40197.1 - 0.51 10.6 19.2 0.29 11.4 17.0 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA OmpH PF03938.14 CDJ40197.1 - 3.2 8.1 25.3 1.6 9.1 5.3 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ndc1_Nup PF09531.10 CDJ40197.1 - 8 5.0 12.9 9.6 4.8 12.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.9 CDJ40198.1 - 8.2e-07 28.9 14.2 8.2e-07 28.9 14.2 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein RL10P_insert PF17777.1 CDJ40200.1 - 2.8e-26 91.3 0.0 4.5e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CDJ40200.1 - 5.5e-12 45.7 1.0 8.5e-12 45.1 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DDHD PF02862.17 CDJ40201.1 - 0.057 13.6 3.7 0.12 12.5 3.6 1.6 2 0 0 2 2 2 0 DDHD domain Afi1 PF07792.12 CDJ40201.1 - 0.27 11.7 9.9 0.53 10.8 9.9 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Peptidase_S15 PF02129.18 CDJ40201.1 - 0.32 10.5 6.2 0.5 9.9 6.2 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) RR_TM4-6 PF06459.12 CDJ40201.1 - 0.34 10.7 7.5 0.51 10.1 7.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ40201.1 - 0.65 8.9 12.8 0.84 8.5 12.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 CDJ40201.1 - 1.2 9.3 7.7 1.9 8.7 7.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.13 CDJ40201.1 - 1.7 9.2 20.9 4 8.1 15.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Conotoxin PF02950.17 CDJ40201.1 - 6.1 7.9 8.0 18 6.5 8.0 1.8 1 0 0 1 1 1 0 Conotoxin MRI PF15325.6 CDJ40202.1 - 0.54 11.4 4.5 0.75 10.9 4.5 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection RskA PF10099.9 CDJ40203.1 - 0.19 12.0 7.9 0.28 11.5 7.9 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Androgen_recep PF02166.16 CDJ40203.1 - 0.35 9.7 8.8 0.54 9.0 8.8 1.2 1 0 0 1 1 1 0 Androgen receptor Exonuc_VII_L PF02601.15 CDJ40203.1 - 0.75 9.3 7.5 0.92 9.0 7.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GcrA PF07750.11 CDJ40203.1 - 1.5 9.3 7.0 0.94 9.9 5.0 1.6 1 1 1 2 2 2 0 GcrA cell cycle regulator TFIIA PF03153.13 CDJ40203.1 - 2.1 8.3 9.3 2.4 8.0 9.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S14 PF00253.21 CDJ40204.1 - 5.4e-11 42.1 5.7 5.9e-11 42.0 5.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 CDJ40204.1 - 0.057 13.3 0.1 0.071 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Cytochrom_c3_2 PF14537.6 CDJ40204.1 - 0.063 13.8 0.1 0.069 13.6 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c3 Cnd2 PF05786.14 CDJ40205.1 - 1.3e-12 47.3 0.1 1.5e-12 47.1 0.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 CDJ40205.1 - 7.6e-06 26.1 1.4 1e-05 25.7 1.4 1.2 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal S-antigen PF05756.11 CDJ40205.1 - 0.037 14.4 0.4 0.051 13.9 0.4 1.2 1 0 0 1 1 1 0 S-antigen protein TMEM208_SND2 PF05620.11 CDJ40205.1 - 0.089 12.6 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Spt20 PF12090.8 CDJ40205.1 - 0.69 9.5 8.9 0.78 9.3 8.9 1.1 1 0 0 1 1 1 0 Spt20 family DUF2897 PF11446.8 CDJ40206.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Metallophos PF00149.28 CDJ40208.1 - 4.1e-22 79.7 0.2 8.2e-22 78.7 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CAP_GLY PF01302.25 CDJ40208.1 - 2.8e-10 40.1 1.4 5.7e-10 39.1 1.4 1.5 1 0 0 1 1 1 1 CAP-Gly domain EF-hand_1 PF00036.32 CDJ40208.1 - 1.1e-09 37.2 0.5 0.00034 19.9 0.1 3.5 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CDJ40208.1 - 2.1e-09 37.7 0.0 0.00021 21.7 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ40208.1 - 7.2e-08 31.8 0.2 0.0087 15.9 0.2 3.5 4 0 0 4 4 4 2 EF-hand domain PPP5 PF08321.12 CDJ40208.1 - 4.7e-06 26.8 0.0 1.5e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 PPP5 TPR repeat region EF-hand_5 PF13202.6 CDJ40208.1 - 2.6e-05 23.5 0.4 0.031 13.8 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CDJ40208.1 - 0.00044 20.0 1.9 0.068 13.0 0.2 4.0 4 1 1 5 5 5 1 EF-hand domain pair IQ PF00612.27 CDJ40208.1 - 0.16 11.9 0.4 0.67 9.9 0.4 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif ATP-grasp_2 PF08442.10 CDJ40209.1 - 3.8e-58 196.4 0.2 1.6e-57 194.4 0.2 1.8 1 1 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CDJ40209.1 - 1.5e-10 41.1 0.1 5.1e-10 39.4 0.1 2.0 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 CDJ40209.1 - 5.8e-08 32.5 0.3 8.6e-07 28.6 0.3 2.1 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CDJ40209.1 - 0.0096 15.7 0.1 0.05 13.4 0.1 2.1 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 CDJ40209.1 - 0.015 14.9 0.4 1.4 8.5 0.0 2.6 2 1 1 3 3 3 0 RimK-like ATP-grasp domain SUIM_assoc PF16619.5 CDJ40209.1 - 0.26 11.4 0.0 0.26 11.4 0.0 4.0 2 2 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SUIM_assoc PF16619.5 CDJ40211.1 - 3.6 7.7 14.6 1.3 9.1 8.2 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FAM199X PF15814.5 CDJ40212.1 - 0.76 8.8 11.1 0.81 8.7 11.1 1.0 1 0 0 1 1 1 0 Protein family FAM199X DUF4013 PF13197.6 CDJ40212.1 - 1.5 8.7 9.2 1.8 8.4 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) Tic110 PF16940.5 CDJ40212.1 - 7.2 5.0 18.4 8.1 4.8 18.4 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter ABC2_membrane_2 PF12679.7 CDJ40213.1 - 0.0089 15.3 1.1 0.016 14.5 0.2 1.9 2 1 0 2 2 2 1 ABC-2 family transporter protein RskA PF10099.9 CDJ40213.1 - 0.015 15.6 16.8 0.015 15.6 16.8 4.1 1 1 1 2 2 1 0 Anti-sigma-K factor rskA MMR1 PF08505.10 CDJ40213.1 - 0.016 15.6 8.8 0.033 14.5 8.8 1.6 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF719 PF05334.13 CDJ40213.1 - 0.018 15.2 2.5 0.018 15.2 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF719) CLN3 PF02487.17 CDJ40213.1 - 0.065 12.3 1.3 0.11 11.5 1.3 1.3 1 0 0 1 1 1 0 CLN3 protein SpoIIP PF07454.11 CDJ40213.1 - 0.076 12.5 6.8 0.13 11.7 6.8 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Methyltransf_34 PF11312.8 CDJ40213.1 - 0.099 11.9 13.8 0.11 11.8 12.5 1.5 1 1 0 1 1 1 0 Putative SAM-dependent methyltransferase Lin-8 PF03353.15 CDJ40213.1 - 0.1 12.1 10.4 0.2 11.2 10.4 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist EIIBC-GUT_N PF03612.14 CDJ40213.1 - 0.12 12.1 5.0 0.29 10.9 5.0 1.7 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus WD40 PF00400.32 CDJ40213.1 - 0.19 12.6 15.8 5.7 8.0 12.2 3.6 2 1 0 2 2 2 0 WD domain, G-beta repeat eIF-3_zeta PF05091.12 CDJ40213.1 - 0.25 10.3 10.1 0.44 9.5 10.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AUX_IAA PF02309.16 CDJ40213.1 - 0.34 10.7 6.0 0.57 10.0 6.0 1.4 1 0 0 1 1 1 0 AUX/IAA family V_ATPase_I PF01496.19 CDJ40213.1 - 0.62 7.9 6.7 0.88 7.4 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4770 PF15994.5 CDJ40213.1 - 0.62 10.3 13.3 0.26 11.5 9.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Peptidase_S49_N PF08496.10 CDJ40213.1 - 0.78 9.8 8.0 2.8 8.0 6.8 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Plasmodium_Vir PF05795.11 CDJ40213.1 - 0.85 9.0 4.4 1.3 8.4 4.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PAT1 PF09770.9 CDJ40213.1 - 0.94 7.7 21.4 1.5 7.0 21.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 CDJ40213.1 - 0.95 8.4 8.3 1.3 7.9 8.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Peroxin-13_N PF04088.13 CDJ40213.1 - 1.2 9.4 4.9 0.58 10.4 2.1 1.8 2 0 0 2 2 2 0 Peroxin 13, N-terminal region YABBY PF04690.13 CDJ40213.1 - 1.3 9.6 10.1 1 9.9 7.4 2.1 1 1 1 2 2 2 0 YABBY protein RED_N PF07808.13 CDJ40213.1 - 1.4 8.4 11.6 0.2 11.2 7.1 1.9 2 0 0 2 2 2 0 RED-like protein N-terminal region Med26_C PF15693.5 CDJ40213.1 - 1.8 8.7 14.2 2.9 8.0 13.3 1.9 1 1 0 1 1 1 0 Mediator complex subunit 26 C-terminal ALMT PF11744.8 CDJ40213.1 - 2.8 6.7 4.6 3.8 6.2 4.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter EMC3_TMCO1 PF01956.16 CDJ40213.1 - 3.1 7.5 5.3 5.6 6.7 5.3 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF1980 PF09323.10 CDJ40213.1 - 3.3 7.6 5.4 7.7 6.4 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) 60KD_IMP PF02096.20 CDJ40213.1 - 3.3 7.6 10.2 8.3 6.3 10.2 1.6 1 0 0 1 1 1 0 60Kd inner membrane protein WRNPLPNID PF15017.6 CDJ40213.1 - 3.8 8.5 13.9 28 5.7 8.9 3.1 3 0 0 3 3 2 0 Putative WW-binding domain and destruction box MDM10 PF12519.8 CDJ40213.1 - 5.9 5.6 8.3 9.3 5.0 8.3 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Peptidase_S64 PF08192.11 CDJ40213.1 - 7 5.0 10.9 9.5 4.6 10.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Paf1 PF03985.13 CDJ40213.1 - 8.1 5.3 14.5 17 4.3 14.5 1.4 1 0 0 1 1 1 0 Paf1 AIF_C PF14721.6 CDJ40213.1 - 9 6.7 8.6 3.1 8.2 4.9 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3347 PF11827.8 CDJ40213.1 - 9.4 6.4 15.2 13 5.9 14.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) SUIM_assoc PF16619.5 CDJ40216.1 - 0.0055 16.7 1.2 0.0055 16.7 1.2 2.3 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Tic110 PF16940.5 CDJ40216.1 - 6.2 5.2 6.1 8 4.8 6.1 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter DUF4179 PF13786.6 CDJ40217.1 - 0.00093 19.6 2.7 2.3 8.8 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4179) Hamartin PF04388.12 CDJ40217.1 - 0.47 9.1 31.4 0.54 8.8 31.4 1.0 1 0 0 1 1 1 0 Hamartin protein PHD_2 PF13831.6 CDJ40218.1 - 5.2e-10 38.7 6.7 1.1e-09 37.7 6.7 1.6 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 CDJ40218.1 - 0.0015 18.4 15.8 0.0015 18.4 15.8 2.2 2 0 0 2 2 2 1 PHD-finger FHIPEP PF00771.20 CDJ40218.1 - 0.36 9.2 0.8 0.46 8.9 0.8 1.1 1 0 0 1 1 1 0 FHIPEP family Cwf_Cwc_15 PF04889.12 CDJ40218.1 - 0.56 9.9 9.2 1 9.0 9.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Trehalose_PPase PF02358.16 CDJ40219.1 - 0.048 12.8 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase FBPase PF00316.20 CDJ40220.1 - 3.2e-08 33.3 0.0 3.2e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Fructose-1-6-bisphosphatase, N-terminal domain Trehalose_PPase PF02358.16 CDJ40220.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Trehalose-phosphatase RskA PF10099.9 CDJ40220.1 - 0.43 10.8 23.2 0.61 10.4 8.1 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF4482 PF14818.6 CDJ40220.1 - 1 10.2 4.3 0.41 11.5 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Cwf_Cwc_15 PF04889.12 CDJ40220.1 - 1.6 8.4 7.5 0.086 12.6 1.8 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Kelch_1 PF01344.25 CDJ40223.1 - 6.6e-05 22.4 0.0 6.8e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.6 CDJ40223.1 - 0.00027 20.9 0.0 0.00028 20.8 0.0 1.0 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ40223.1 - 0.0016 18.7 0.0 0.0016 18.6 0.0 1.0 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.15 CDJ40223.1 - 0.0063 16.4 0.0 0.0066 16.4 0.0 1.1 1 0 0 1 1 1 1 Kelch motif Kelch_3 PF13415.6 CDJ40223.1 - 0.015 15.6 0.0 0.015 15.5 0.0 1.0 1 0 0 1 1 1 0 Galactose oxidase, central domain Peptidase_M1 PF01433.20 CDJ40226.1 - 6.8e-21 74.8 0.0 8.8e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 CDJ40226.1 - 2.6e-12 47.0 0.1 4.9e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Brr6_like_C_C PF10104.9 CDJ40227.1 - 2.1e-23 82.5 0.1 2.9e-23 82.1 0.1 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PAP2 PF01569.21 CDJ40227.1 - 0.025 14.4 4.0 0.018 14.8 2.1 1.7 1 1 1 2 2 2 0 PAP2 superfamily EIF4E-T PF10477.9 CDJ40227.1 - 0.19 10.5 1.9 0.24 10.2 1.9 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E CcmF_C PF16327.5 CDJ40227.1 - 0.29 10.4 4.7 0.11 11.7 0.8 1.8 2 0 0 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal YajC PF02699.15 CDJ40227.1 - 0.37 10.7 1.6 3.4 7.6 0.8 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit RskA PF10099.9 CDJ40227.1 - 0.79 10.0 8.7 1.7 8.9 8.7 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DivIC PF04977.15 CDJ40227.1 - 2.4 8.0 11.1 6.6 6.6 6.8 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF4878 PF12870.7 CDJ40228.1 - 0.0027 18.0 0.2 0.0027 18.0 0.2 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4878) DUF2815 PF10991.8 CDJ40228.1 - 2.5 8.0 7.0 0.13 12.2 0.5 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2815) Secretin_N_2 PF07655.13 CDJ40230.1 - 0.075 13.6 29.6 2.8 8.6 0.3 3.3 3 0 0 3 3 3 0 Secretin N-terminal domain Hamartin PF04388.12 CDJ40230.1 - 1.8 7.1 16.1 2.6 6.6 16.1 1.2 1 0 0 1 1 1 0 Hamartin protein IMUP PF15761.5 CDJ40230.1 - 3.8 8.3 36.4 2.9 8.6 3.4 4.2 3 0 0 3 3 3 0 Immortalisation up-regulated protein Kinetochor_Ybp2 PF08568.10 CDJ40231.1 - 0.015 13.9 0.3 0.015 13.9 0.3 1.4 2 0 0 2 2 2 0 Uncharacterised protein family, YAP/Alf4/glomulin Activator_LAG-3 PF11498.8 CDJ40231.1 - 4.2 6.2 20.4 4.9 6.0 2.1 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SR-25 PF10500.9 CDJ40232.1 - 0.064 12.8 4.7 0.093 12.3 4.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 CDJ40233.1 - 8.7e-36 123.6 0.0 9.4e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ40233.1 - 4.6e-14 52.3 0.0 4.9e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ40233.1 - 0.0064 15.3 0.0 0.0073 15.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ40233.1 - 0.011 15.1 0.1 0.013 14.9 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ40233.1 - 0.015 14.2 0.1 0.017 14.0 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CDJ40233.1 - 0.025 13.6 0.2 0.031 13.3 0.2 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 CDJ40233.1 - 0.057 12.7 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like SUIM_assoc PF16619.5 CDJ40234.1 - 0.11 12.6 2.3 0.38 10.8 0.2 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 CDJ40234.1 - 4 6.5 5.9 4.8 6.3 5.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TMEM100 PF16311.5 CDJ40235.1 - 0.024 14.2 0.1 0.076 12.6 0.1 1.9 1 0 0 1 1 1 0 Transmembrane protein 100 FAM176 PF14851.6 CDJ40235.1 - 0.51 10.0 0.0 0.51 10.0 0.0 3.9 3 1 2 5 5 5 0 FAM176 family SR-25 PF10500.9 CDJ40236.1 - 0.57 9.8 12.8 0.79 9.3 12.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 CDJ40236.1 - 6.3 5.0 5.0 8.3 4.6 5.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PrmA PF06325.13 CDJ40238.1 - 1.2e-06 28.1 0.1 2.1e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 CDJ40238.1 - 2.7e-06 27.2 0.4 5.2e-06 26.2 0.4 1.5 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 CDJ40238.1 - 3.3e-06 27.0 0.1 8e-06 25.8 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ40238.1 - 7.9e-06 26.5 1.4 0.00027 21.6 1.4 2.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ40238.1 - 4.8e-05 23.0 0.9 8.9e-05 22.1 0.6 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 CDJ40238.1 - 0.00021 21.1 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 CDJ40238.1 - 0.0077 16.9 0.4 0.038 14.7 0.4 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ40238.1 - 0.013 15.3 0.2 0.027 14.3 0.2 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 CDJ40238.1 - 0.024 14.4 0.1 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 Lysine methyltransferase PRMT5 PF05185.16 CDJ40238.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase DOT1 PF08123.13 CDJ40238.1 - 0.23 11.0 0.1 0.4 10.2 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 YajC PF02699.15 CDJ40238.1 - 2.7 7.9 3.9 1.9 8.4 1.5 1.9 2 0 0 2 2 2 0 Preprotein translocase subunit CAP_N PF01213.19 CDJ40238.1 - 9.7 5.6 16.0 5.4 6.4 10.2 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF2400 PF09674.10 CDJ40239.1 - 0.14 12.2 5.7 0.16 12.0 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) CENP-K PF11802.8 CDJ40239.1 - 0.14 11.7 20.3 0.18 11.3 20.3 1.1 1 0 0 1 1 1 0 Centromere-associated protein K TFIIA PF03153.13 CDJ40239.1 - 0.27 11.2 28.2 0.45 10.5 28.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit C_GCAxxG_C_C PF09719.10 CDJ40239.1 - 0.28 11.5 7.1 0.22 11.8 5.4 1.7 1 1 1 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) FapA PF03961.13 CDJ40239.1 - 0.48 9.0 10.7 0.56 8.7 10.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 CDJ40239.1 - 0.56 10.3 22.2 0.8 9.8 22.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 CDJ40239.1 - 4.4 5.1 13.5 4.5 5.1 13.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SR-25 PF10500.9 CDJ40240.1 - 2 8.0 12.8 2.6 7.6 12.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF746 PF05344.11 CDJ40241.1 - 0.0066 16.3 0.3 0.015 15.2 0.3 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF746) HTH_23 PF13384.6 CDJ40241.1 - 0.0093 15.7 0.2 0.0093 15.7 0.2 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ40241.1 - 0.012 15.8 0.2 0.012 15.8 0.2 3.2 5 0 0 5 5 5 0 Helix-turn-helix domain PhoH PF02562.16 CDJ40241.1 - 0.057 12.9 1.0 0.078 12.4 1.0 1.2 1 0 0 1 1 1 0 PhoH-like protein HTH_Tnp_1 PF01527.20 CDJ40241.1 - 0.19 12.1 9.4 0.73 10.2 2.2 2.7 2 1 1 3 3 3 0 Transposase Fe_hyd_lg_C PF02906.14 CDJ40242.1 - 2.1e-09 37.4 0.0 3.7e-06 26.8 0.0 2.4 3 0 0 3 3 3 2 Iron only hydrogenase large subunit, C-terminal domain RNA_pol_Rpc34 PF05158.12 CDJ40242.1 - 0.21 10.9 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit zinc_ribbon_6 PF14599.6 CDJ40243.1 - 0.087 12.8 1.2 0.14 12.2 1.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon Pal1 PF08316.11 CDJ40243.1 - 0.12 13.1 1.2 0.13 13.0 1.2 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein Spt20 PF12090.8 CDJ40243.1 - 0.27 10.8 17.8 0.34 10.5 17.8 1.1 1 0 0 1 1 1 0 Spt20 family MPM1 PF17234.2 CDJ40243.1 - 0.89 9.8 7.2 0.97 9.7 7.2 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF2722 PF10846.8 CDJ40243.1 - 1.5 7.7 15.1 2.1 7.2 15.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4407 PF14362.6 CDJ40243.1 - 7.3 5.8 10.4 8.3 5.7 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PP2C PF00481.21 CDJ40244.1 - 8.1e-14 51.9 0.3 1e-13 51.6 0.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ40244.1 - 0.0099 15.8 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PH PF00169.29 CDJ40246.1 - 0.00061 20.3 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 PH domain SUIM_assoc PF16619.5 CDJ40246.1 - 0.0052 16.8 28.2 0.94 9.6 8.1 3.4 3 0 0 3 3 3 3 Unstructured region C-term to UIM in Ataxin3 DUF2076 PF09849.9 CDJ40246.1 - 0.089 12.8 22.0 0.075 13.1 15.7 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Ndc1_Nup PF09531.10 CDJ40246.1 - 0.37 9.4 7.3 0.055 12.2 3.3 1.6 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF3123 PF11321.8 CDJ40246.1 - 0.41 11.3 3.6 7.7 7.2 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3123) Ribosomal_60s PF00428.19 CDJ40246.1 - 3 8.5 13.5 0.34 11.5 2.6 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF3391 PF11871.8 CDJ40246.1 - 4 8.0 8.4 1.8 9.1 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Rpp20 PF12328.8 CDJ40246.1 - 6.7 6.7 6.1 7.5 6.5 0.0 2.7 3 0 0 3 3 3 0 Rpp20 subunit of nuclear RNase MRP and P PsbY PF06298.11 CDJ40247.1 - 9.1 6.3 9.9 0.43 10.5 0.7 2.8 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) SUIM_assoc PF16619.5 CDJ40248.1 - 0.00024 21.1 2.0 0.00024 21.1 2.0 15.0 7 5 3 10 10 10 3 Unstructured region C-term to UIM in Ataxin3 CDC45 PF02724.14 CDJ40248.1 - 0.00057 18.3 4.0 0.00057 18.3 4.0 4.0 4 1 0 4 4 4 2 CDC45-like protein Ank_4 PF13637.6 CDJ40249.1 - 3.6e-06 27.4 0.1 6.2e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ40249.1 - 1e-05 25.5 0.0 0.091 13.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 CDJ40249.1 - 1.3e-05 25.7 0.1 2.1e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ40249.1 - 3e-05 24.2 1.1 0.0044 17.4 0.2 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CDJ40249.1 - 0.097 13.0 0.2 0.46 10.9 0.0 2.0 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Presenilin PF01080.17 CDJ40249.1 - 0.3 9.8 2.0 0.31 9.8 2.0 1.1 1 0 0 1 1 1 0 Presenilin SOG2 PF10428.9 CDJ40249.1 - 1.1 8.4 7.9 1.3 8.1 7.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF5427 PF10310.9 CDJ40249.1 - 3.6 6.4 12.3 4.5 6.1 12.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Ndc1_Nup PF09531.10 CDJ40249.1 - 5.3 5.6 7.6 5.5 5.6 7.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FTZ PF03867.14 CDJ40249.1 - 5.7 6.4 12.3 5.3 6.5 11.5 1.3 1 1 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Neur_chan_memb PF02932.16 CDJ40249.1 - 9 6.3 5.8 12 5.9 5.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dehydrin PF00257.19 CDJ40250.1 - 8.2 7.0 11.0 0.77 10.3 4.9 2.0 1 1 1 2 2 2 0 Dehydrin DUF494 PF04361.13 CDJ40251.1 - 0.07 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF494) TFIIA PF03153.13 CDJ40251.1 - 0.099 12.6 21.9 0.13 12.2 21.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ40251.1 - 0.1 12.2 3.9 0.14 11.8 3.9 1.2 1 0 0 1 1 1 0 Spt20 family DUF966 PF06136.13 CDJ40251.1 - 0.55 9.9 4.1 0.79 9.4 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Endomucin PF07010.12 CDJ40251.1 - 1.3 8.9 9.4 2.3 8.2 9.4 1.4 1 0 0 1 1 1 0 Endomucin Ndc1_Nup PF09531.10 CDJ40251.1 - 8.6 4.9 8.4 13 4.3 8.3 1.5 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Diphthamide_syn PF01866.17 CDJ40252.1 - 0.026 14.0 0.0 0.057 12.9 0.0 1.5 2 0 0 2 2 2 0 Putative diphthamide synthesis protein FAM60A PF15396.6 CDJ40252.1 - 0.84 9.6 4.8 3.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Spc7_N PF15402.6 CDJ40252.1 - 2.4 6.3 13.3 0.047 12.0 2.0 2.1 2 0 0 2 2 2 0 N-terminus of kinetochore NMS complex subunit Spc7 RskA PF10099.9 CDJ40252.1 - 5.1 7.4 16.2 2.4 8.4 10.7 2.4 2 1 0 2 2 2 0 Anti-sigma-K factor rskA BAF1_ABF1 PF04684.13 CDJ40255.1 - 1.7 7.6 13.3 1.9 7.4 13.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FAM199X PF15814.5 CDJ40255.1 - 7.1 5.6 9.2 8.5 5.3 9.2 1.1 1 0 0 1 1 1 0 Protein family FAM199X SLBP_RNA_bind PF15247.6 CDJ40256.1 - 1.1e-18 67.0 2.2 1.1e-18 67.0 2.2 2.5 2 1 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain SR-25 PF10500.9 CDJ40256.1 - 0.0033 17.1 6.6 0.0039 16.8 6.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein UPF0524 PF15823.5 CDJ40256.1 - 0.29 10.5 4.3 0.42 10.0 4.3 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 Ndc1_Nup PF09531.10 CDJ40256.1 - 0.49 9.0 9.3 0.57 8.8 9.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDK2AP PF09806.9 CDJ40256.1 - 0.54 10.3 8.9 0.71 9.9 8.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PTH2 PF01981.16 CDJ40256.1 - 1.5 9.1 4.6 1 9.6 3.0 1.5 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 IMUP PF15761.5 CDJ40257.1 - 0.08 13.6 6.1 0.086 13.5 6.1 1.1 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ40257.1 - 0.28 10.8 7.4 0.27 10.8 7.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATP-synt_ab PF00006.25 CDJ40258.1 - 3.6e-65 219.6 0.0 5.1e-65 219.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDJ40258.1 - 4.4e-10 39.9 0.2 8.1e-10 39.1 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RskA PF10099.9 CDJ40259.1 - 0.0025 18.2 0.9 0.0025 18.2 0.9 4.8 2 2 2 4 4 4 1 Anti-sigma-K factor rskA DUF1645 PF07816.11 CDJ40259.1 - 0.0094 16.5 4.2 0.0094 16.5 4.2 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF1645) DUF1522 PF07482.11 CDJ40259.1 - 0.32 11.3 0.1 0.32 11.3 0.1 3.6 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1522) Secretin_N_2 PF07655.13 CDJ40259.1 - 0.92 10.1 20.4 2.3 8.8 20.4 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Apt1 PF10351.9 CDJ40259.1 - 6.1 5.6 8.1 0.23 10.3 1.8 1.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain TFIIA PF03153.13 CDJ40259.1 - 8.7 6.2 27.4 0.86 9.5 9.5 2.6 1 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CRT-like PF08627.10 CDJ40260.1 - 0.00018 20.6 5.5 0.00048 19.2 4.8 1.9 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Spt20 PF12090.8 CDJ40260.1 - 0.00027 20.6 9.2 0.00035 20.3 9.2 1.1 1 0 0 1 1 1 1 Spt20 family GTA_holin_3TM PF11351.8 CDJ40260.1 - 0.0079 16.7 0.1 0.0079 16.7 0.1 2.2 1 1 1 2 2 2 1 Holin of 3TMs, for gene-transfer release DUF702 PF05142.12 CDJ40260.1 - 0.033 14.7 1.2 0.058 13.9 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Kei1 PF08552.11 CDJ40260.1 - 0.035 14.0 0.6 0.035 14.0 0.6 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 FAM60A PF15396.6 CDJ40260.1 - 0.11 12.4 0.3 0.15 12.0 0.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A GREB1 PF15782.5 CDJ40260.1 - 0.12 9.4 2.8 0.14 9.2 2.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF755 PF05501.11 CDJ40260.1 - 0.14 12.5 14.9 0.19 12.0 14.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Miga PF10265.9 CDJ40260.1 - 0.21 10.6 7.3 0.29 10.1 7.3 1.1 1 0 0 1 1 1 0 Mitoguardin TFIIA PF03153.13 CDJ40260.1 - 1.4 8.8 17.8 1.8 8.5 17.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ40260.1 - 7.7 6.0 10.2 9.9 5.6 10.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Rrn6 PF10214.9 CDJ40260.1 - 7.8 4.8 14.4 9.8 4.5 14.4 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4199 PF13858.6 CDJ40260.1 - 9.4 6.6 11.2 0.15 12.5 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) eIF-3_zeta PF05091.12 CDJ40260.1 - 9.9 5.0 9.4 12 4.7 9.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SKA2 PF16740.5 CDJ40261.1 - 1.4e-06 28.0 2.4 1.9e-06 27.6 2.4 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Vps5 PF09325.10 CDJ40261.1 - 0.045 13.3 0.1 1 8.8 0.0 2.1 1 1 0 2 2 2 0 Vps5 C terminal like Pex16 PF08610.10 CDJ40261.1 - 0.11 11.6 0.3 0.19 10.9 0.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) EccE PF11203.8 CDJ40261.1 - 0.16 12.3 3.3 0.2 12.0 2.0 1.7 1 1 1 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Muted PF14942.6 CDJ40261.1 - 0.16 12.3 0.8 0.22 11.8 0.6 1.4 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Ribophorin_I PF04597.14 CDJ40262.1 - 1.2e-65 222.5 0.0 1.7e-65 222.0 0.0 1.3 1 0 0 1 1 1 1 Ribophorin I DUF3632 PF12311.8 CDJ40262.1 - 0.064 13.7 0.0 0.064 13.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3632) DUF1488 PF07369.11 CDJ40262.1 - 0.087 12.8 2.4 0.14 12.2 0.3 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1488) AATF-Che1 PF13339.6 CDJ40262.1 - 0.17 12.6 4.7 0.45 11.2 4.7 1.7 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor AgrD PF05931.11 CDJ40262.1 - 0.2 11.7 0.1 0.48 10.5 0.1 1.6 1 0 0 1 1 1 0 Staphylococcal AgrD protein zf-MYND PF01753.18 CDJ40263.1 - 5.3e-12 45.6 6.8 2e-11 43.7 6.8 2.1 1 0 0 1 1 1 1 MYND finger SET PF00856.28 CDJ40263.1 - 9.3e-10 39.1 0.0 3.8e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 SET domain B56 PF01603.20 CDJ40266.1 - 1.4e-162 541.5 5.7 1.7e-162 541.1 5.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 CDJ40266.1 - 0.2 11.5 4.6 0.17 11.7 0.5 2.8 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DNA_ligase_aden PF01653.18 CDJ40267.1 - 1.7e-43 148.9 0.0 2.2e-13 50.0 0.1 5.8 3 1 1 4 4 4 4 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 CDJ40267.1 - 6e-24 83.7 0.2 1.2e-23 82.8 0.2 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain Wyosine_form PF08608.12 CDJ40268.1 - 1e-18 67.4 0.0 2.4e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 CDJ40268.1 - 1.9e-17 64.2 0.0 3.5e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily CMD PF02627.20 CDJ40268.1 - 0.041 13.9 0.2 0.13 12.3 0.2 1.8 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Hydrolase PF00702.26 CDJ40268.1 - 0.058 13.7 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ELYS PF13934.6 CDJ40268.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.2 3 0 0 3 3 3 0 Nuclear pore complex assembly Miff PF05644.11 CDJ40269.1 - 0.52 9.9 7.7 1 8.9 7.7 1.4 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Ocnus PF05005.15 CDJ40270.1 - 8.1e-22 77.4 0.3 1.4e-21 76.7 0.3 1.3 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) MukB_hinge PF16330.5 CDJ40270.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 MukB hinge domain E1_dh PF00676.20 CDJ40271.1 - 3.6e-82 275.7 0.0 4.5e-82 275.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 CDJ40271.1 - 3.6e-11 43.1 0.2 7.9e-11 42.0 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 CDJ40271.1 - 7.7e-05 22.0 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 CDJ40271.1 - 0.00034 19.7 0.0 0.00051 19.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain MAR_sialic_bdg PF10564.9 CDJ40272.1 - 3.7e-23 81.4 0.8 5.6e-23 80.8 0.8 1.3 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat NOG1_N PF17835.1 CDJ40273.1 - 0.0046 16.9 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 1 NOG1 N-terminal helical domain BBS2_N PF14781.6 CDJ40274.1 - 3.7 7.5 5.5 3.1 7.7 0.5 3.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal MAR_sialic_bdg PF10564.9 CDJ40275.1 - 2.2e-135 441.1 54.1 4.8e-26 90.6 4.8 6.4 6 0 0 6 6 6 6 Sialic-acid binding micronemal adhesive repeat FAM25 PF15825.5 CDJ40275.1 - 0.0012 19.2 0.6 17 5.8 0.0 3.7 3 0 0 3 3 3 2 FAM25 family Calci_bind_CcbP PF11535.8 CDJ40275.1 - 0.0079 16.7 0.0 71 4.0 0.0 4.4 4 0 0 4 4 4 0 Calcium binding Ribosomal_L6e_N PF03868.15 CDJ40275.1 - 0.0094 16.2 3.4 22 5.4 0.1 3.6 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain DUF3391 PF11871.8 CDJ40275.1 - 0.021 15.4 6.4 10 6.7 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) Myotub-related PF06602.14 CDJ40275.1 - 0.041 12.8 0.5 37 3.1 0.0 3.3 3 0 0 3 3 3 0 Myotubularin-like phosphatase domain DUF1652 PF07865.11 CDJ40275.1 - 0.08 12.8 0.1 87 3.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) Herpes_IE2_3 PF03361.14 CDJ40275.1 - 0.64 9.9 6.6 45 3.9 0.2 3.4 3 0 0 3 3 3 0 Herpes virus intermediate/early protein 2/3 Prenyltrans PF00432.21 CDJ40276.1 - 3e-18 65.3 23.8 5.9e-09 35.5 0.0 8.0 8 1 0 8 8 8 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CDJ40276.1 - 0.027 13.6 0.0 0.1 11.6 0.0 1.9 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain NUDIX PF00293.28 CDJ40277.1 - 0.0014 18.6 0.3 0.0035 17.4 0.1 1.7 2 0 0 2 2 2 1 NUDIX domain FANCF PF11107.8 CDJ40277.1 - 0.0033 16.7 1.9 0.0052 16.1 1.9 1.3 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) HydF_tetramer PF18133.1 CDJ40277.1 - 0.038 13.7 0.1 0.066 13.0 0.1 1.3 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain MRP-L46 PF11788.8 CDJ40277.1 - 0.3 11.8 7.3 0.76 10.5 7.3 1.8 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Phosducin PF02114.16 CDJ40277.1 - 0.52 9.2 3.5 0.83 8.5 3.5 1.3 1 0 0 1 1 1 0 Phosducin LSM PF01423.22 CDJ40278.1 - 6.4e-20 70.6 0.0 7.7e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CDJ40278.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.5 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Clathrin PF00637.20 CDJ40283.1 - 2.4e-168 552.7 21.0 1.3e-28 99.6 0.4 7.6 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CDJ40283.1 - 3.6e-26 90.9 0.5 1.5e-25 88.9 0.1 2.4 2 0 0 2 2 2 1 Clathrin-H-link Coatomer_WDAD PF04053.14 CDJ40283.1 - 7.6e-08 31.8 2.0 0.18 10.8 0.0 3.7 4 0 0 4 4 4 3 Coatomer WD associated region Clathrin_propel PF01394.20 CDJ40283.1 - 1.6e-07 31.3 0.0 5.5e-05 23.3 0.0 4.1 4 0 0 4 4 4 1 Clathrin propeller repeat Ribosomal_S24e PF01282.19 CDJ40283.1 - 0.035 14.0 0.0 0.53 10.3 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S24e TPR_1 PF00515.28 CDJ40283.1 - 0.047 13.5 3.4 31 4.6 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ40283.1 - 0.13 12.7 0.1 17 6.1 0.0 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 CDJ40283.1 - 0.15 12.1 1.0 0.35 11.0 0.1 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TPR_19 PF14559.6 CDJ40283.1 - 0.17 12.4 7.2 0.76 10.3 0.4 5.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ40283.1 - 1.9 8.8 0.0 1.9 8.8 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ40283.1 - 5.5 7.9 6.6 5.2 8.0 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Sugar_tr PF00083.24 CDJ40285.1 - 4.3e-82 276.4 26.9 5.1e-82 276.1 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ40285.1 - 4.2e-34 118.0 59.8 4e-25 88.5 35.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CDJ40285.1 - 0.039 12.2 10.7 0.0022 16.4 5.0 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Holin_SPP1 PF04688.13 CDJ40285.1 - 2 8.6 6.9 2.4 8.4 1.2 3.2 2 0 0 2 2 2 0 SPP1 phage holin Frataxin_Cyay PF01491.16 CDJ40286.1 - 3.1e-22 78.7 0.0 4.2e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Patatin PF01734.22 CDJ40288.1 - 1.7e-05 25.1 2.5 9.8e-05 22.6 2.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase DUF1205 PF06722.12 CDJ40288.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) ATG7_N PF16420.5 CDJ40289.1 - 7.5e-23 81.6 6.0 1e-13 51.6 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 CDJ40289.1 - 3.2e-13 49.6 0.0 1.2e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 ThiF family OTU PF02338.19 CDJ40290.1 - 1.8e-15 57.6 0.0 3.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDJ40290.1 - 0.038 13.4 0.0 3 7.2 0.0 2.4 1 1 1 2 2 2 0 Peptidase C65 Otubain Mito_carr PF00153.27 CDJ40293.1 - 1.2e-55 185.4 0.3 1.1e-18 66.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DNA_pol_B PF00136.21 CDJ40294.1 - 1.1e-138 462.8 0.6 1.5e-138 462.4 0.6 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CDJ40294.1 - 3e-73 246.9 0.0 5e-73 246.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CDJ40294.1 - 3.8e-17 62.5 6.3 1.2e-16 60.9 6.3 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CDJ40294.1 - 0.0088 14.9 0.1 0.074 11.9 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 CDJ40294.1 - 0.16 11.6 0.0 0.41 10.3 0.0 1.6 1 1 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB zf-RING-like PF08746.11 CDJ40294.1 - 3.6 8.0 9.9 2.2 8.7 0.3 2.9 3 0 0 3 3 3 0 RING-like domain AAA_2 PF07724.14 CDJ40295.1 - 3.2e-24 85.9 0.0 3.6e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CDJ40295.1 - 1.9e-05 25.1 0.0 2.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CDJ40295.1 - 0.0034 17.4 0.0 0.0067 16.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CDJ40296.1 - 2.1e-07 31.4 0.0 4.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ40296.1 - 1.4e-06 28.3 0.0 2.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDJ40296.1 - 1.9e-06 28.1 0.0 3.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ40296.1 - 9e-06 26.0 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CDJ40296.1 - 1.1e-05 24.8 0.2 1.7e-05 24.2 0.2 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain MCM PF00493.23 CDJ40296.1 - 1.7e-05 24.1 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 CDJ40296.1 - 2.5e-05 24.7 0.1 4.6e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CDJ40296.1 - 5.7e-05 23.7 0.0 9.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDJ40296.1 - 0.00055 19.4 0.1 0.0081 15.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CDJ40296.1 - 0.0018 18.4 0.1 0.0048 17.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 CDJ40296.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CDJ40296.1 - 0.0024 18.1 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CDJ40296.1 - 0.0029 16.9 0.1 0.0056 16.0 0.1 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_3 PF07726.11 CDJ40296.1 - 0.0034 17.2 0.1 0.16 11.8 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ40296.1 - 0.0037 17.0 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 CDJ40296.1 - 0.0039 16.7 0.0 0.0064 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 CDJ40296.1 - 0.0061 16.6 0.0 0.0093 16.0 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 CDJ40296.1 - 0.0062 16.3 0.1 0.026 14.3 0.0 1.8 1 1 1 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.6 CDJ40296.1 - 0.0068 16.7 0.1 0.012 15.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.25 CDJ40296.1 - 0.0071 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 CDJ40296.1 - 0.022 14.5 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 CDJ40296.1 - 0.023 14.8 0.1 0.067 13.3 0.0 1.9 2 1 0 2 2 1 0 Shikimate kinase RsgA_GTPase PF03193.16 CDJ40296.1 - 0.037 13.9 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 CDJ40296.1 - 0.041 14.3 0.0 0.078 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IPT PF01745.16 CDJ40296.1 - 0.042 13.2 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Isopentenyl transferase NTPase_1 PF03266.15 CDJ40296.1 - 0.046 13.6 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 NTPase TniB PF05621.11 CDJ40296.1 - 0.05 13.0 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ResIII PF04851.15 CDJ40296.1 - 0.056 13.5 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CPT PF07931.12 CDJ40296.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein SRP54 PF00448.22 CDJ40296.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 CDJ40296.1 - 0.077 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_6 PF12774.7 CDJ40296.1 - 0.093 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region PduV-EutP PF10662.9 CDJ40296.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 CDJ40296.1 - 0.1 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 CDJ40296.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.7 CDJ40296.1 - 0.15 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 AAA_17 PF13207.6 CDJ40296.1 - 0.15 12.5 0.1 0.47 10.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain CLAMP PF14769.6 CDJ40297.1 - 7.9e-17 61.5 0.5 1.4e-16 60.7 0.5 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Pro_isomerase PF00160.21 CDJ40298.1 - 1.9e-34 119.2 0.0 1.6e-33 116.2 0.0 1.9 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RskA PF10099.9 CDJ40298.1 - 0.86 9.9 5.3 0.64 10.3 3.0 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA ADP_PFK_GK PF04587.15 CDJ40299.1 - 0.061 11.9 1.4 0.11 11.1 1.4 1.3 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region BRO1 PF03097.18 CDJ40300.1 - 1.6e-12 46.9 0.1 1.6e-12 46.9 0.1 3.1 3 1 0 3 3 3 1 BRO1-like domain PMC2NT PF08066.12 CDJ40300.1 - 0.011 16.4 0.3 0.011 16.4 0.3 3.7 4 1 1 5 5 5 0 PMC2NT (NUC016) domain DUF2573 PF10835.8 CDJ40300.1 - 0.23 11.8 1.3 20 5.6 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2573) C_Hendra PF16821.5 CDJ40301.1 - 0.076 12.9 3.4 4.7 7.1 0.0 2.6 2 0 0 2 2 2 0 C protein from hendra and measles viruses Pkinase PF00069.25 CDJ40307.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ40307.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Sec63 PF02889.16 CDJ40308.1 - 6.6e-147 487.5 0.0 1.4e-85 286.6 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CDJ40308.1 - 6.8e-43 146.5 0.1 1.7e-25 89.8 0.2 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CDJ40308.1 - 1.4e-32 112.2 0.7 4.7e-32 110.5 0.7 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 CDJ40308.1 - 7.9e-18 65.0 0.0 3e-13 50.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ40308.1 - 3.2e-14 53.2 0.0 2.1e-07 31.2 0.0 3.7 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA PF00004.29 CDJ40308.1 - 0.11 12.9 0.0 0.51 10.8 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) YL1 PF05764.13 CDJ40308.1 - 3.8 7.6 15.9 0.087 12.9 8.5 2.0 1 1 0 2 2 2 0 YL1 nuclear protein UPF0524 PF15823.5 CDJ40309.1 - 0.012 15.0 1.5 0.012 15.0 1.5 3.6 4 0 0 4 4 4 0 UPF0524 of C3orf70 Pkinase PF00069.25 CDJ40309.1 - 1.9 7.8 0.0 1.9 7.8 0.0 2.7 3 0 0 3 3 3 0 Protein kinase domain Apt1 PF10351.9 CDJ40310.1 - 1.3 7.8 16.3 0.018 13.9 5.6 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Sec16 PF12932.7 CDJ40310.1 - 3.1 8.4 10.6 3 8.4 4.8 2.7 2 1 1 3 3 3 0 Vesicle coat trafficking protein Sec16 mid-region DUF755 PF05501.11 CDJ40311.1 - 0.0084 16.4 5.6 0.0084 16.4 5.6 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF755) SUIM_assoc PF16619.5 CDJ40311.1 - 0.012 15.6 6.8 0.012 15.6 6.8 3.4 3 1 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 GAIN PF16489.5 CDJ40311.1 - 0.034 13.6 0.1 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain IMUP PF15761.5 CDJ40311.1 - 0.056 14.1 3.9 0.056 14.1 3.9 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein Med15 PF09606.10 CDJ40311.1 - 0.1 11.3 10.4 0.14 10.8 10.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.13 CDJ40311.1 - 3 8.5 11.7 7.8 7.1 7.9 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AF-4 PF05110.13 CDJ40312.1 - 0.014 13.5 10.7 0.018 13.2 10.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TFIIA PF03153.13 CDJ40312.1 - 0.36 10.8 12.1 0.57 10.1 12.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ40312.1 - 3.6 7.0 8.6 5.2 6.5 8.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Med15 PF09606.10 CDJ40313.1 - 2.4 6.7 23.6 3.5 6.2 23.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CoA_binding PF02629.19 CDJ40314.1 - 5.5e-05 23.8 0.5 5.5e-05 23.8 0.5 1.7 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CDJ40314.1 - 0.00043 20.1 0.1 0.00043 20.1 0.1 1.5 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 CDJ40314.1 - 0.018 14.9 0.2 0.027 14.3 0.2 1.2 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CDJ40314.1 - 0.019 15.5 0.2 0.12 12.8 0.2 1.9 2 0 0 2 2 2 0 CoA binding domain zf-RING_2 PF13639.6 CDJ40315.1 - 0.0028 17.9 2.3 0.004 17.4 2.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CDJ40315.1 - 0.0057 16.4 1.2 0.0057 16.4 1.2 1.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDJ40316.1 - 4.6e-08 32.8 12.4 1.7e-07 30.9 12.4 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ40316.1 - 4.5e-07 30.1 11.6 1.4e-06 28.5 11.6 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ40316.1 - 1.7e-06 27.7 9.2 4.7e-06 26.4 9.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ40316.1 - 2.1e-05 24.3 11.3 8e-05 22.4 11.3 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ40316.1 - 5.2e-05 23.2 11.6 0.00019 21.4 11.6 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ40316.1 - 0.0001 22.2 9.8 0.0001 22.2 9.8 2.3 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ40316.1 - 0.00013 21.7 9.9 0.00047 20.0 9.9 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CDJ40316.1 - 0.001 18.9 4.3 0.0026 17.6 4.3 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 CDJ40316.1 - 0.0026 17.9 14.5 0.0099 16.0 14.5 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Peptidase_C97 PF05903.14 CDJ40316.1 - 0.037 13.9 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain U-box PF04564.15 CDJ40316.1 - 0.064 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-rbx1 PF12678.7 CDJ40316.1 - 2.6 8.4 12.5 2.3 8.5 7.7 3.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain Peptidase_M22 PF00814.25 CDJ40317.1 - 3.2e-07 30.3 7.5 0.069 12.8 0.2 3.2 3 0 0 3 3 3 3 Glycoprotease family TAF4 PF05236.14 CDJ40317.1 - 0.00012 21.9 0.5 0.00012 21.9 0.5 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Lin-8 PF03353.15 CDJ40317.1 - 1.8 8.1 15.3 2.4 7.7 15.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 CDJ40317.1 - 2.5 6.3 25.3 3.2 5.9 25.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Folliculin PF11704.8 CDJ40317.1 - 3.1 7.6 10.7 5.6 6.8 10.7 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport TFIIA PF03153.13 CDJ40317.1 - 3.3 7.6 38.2 0.096 12.7 32.0 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribonuc_P_40 PF08584.11 CDJ40317.1 - 3.3 6.9 7.3 4.7 6.4 7.3 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit DUF4366 PF14283.6 CDJ40317.1 - 5.9 6.9 9.3 2.2 8.3 5.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF1387 PF07139.11 CDJ40317.1 - 6.4 6.4 13.7 8.9 6.0 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) RR_TM4-6 PF06459.12 CDJ40317.1 - 7.1 6.4 14.5 10 5.8 14.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPL PF17800.1 CDJ40318.1 - 4e-11 43.4 0.0 4.9e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoplasmin-like domain DAP_epimerase PF01678.19 CDJ40319.1 - 0.022 14.9 0.8 0.083 13.1 0.8 2.0 1 0 0 1 1 1 0 Diaminopimelate epimerase SR-25 PF10500.9 CDJ40319.1 - 5.6 6.5 43.4 0.65 9.6 21.0 3.9 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein STN1_2 PF09170.10 CDJ40320.1 - 1.9 8.7 18.7 2.3 8.4 18.7 1.2 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 DUF4820 PF16091.5 CDJ40320.1 - 2.3 7.5 9.4 2.7 7.3 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Egg_lysin PF01303.17 CDJ40321.1 - 0.028 14.7 0.1 0.044 14.0 0.1 1.3 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) Menin PF05053.13 CDJ40321.1 - 0.065 11.6 9.5 0.1 11.0 9.5 1.2 1 0 0 1 1 1 0 Menin TMEM237 PF15383.6 CDJ40321.1 - 0.74 8.9 7.7 0.04 13.0 1.8 2.0 2 0 0 2 2 2 0 Transmembrane protein 237 Macoilin PF09726.9 CDJ40323.1 - 0.26 9.8 22.4 0.38 9.2 22.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF572 PF04502.13 CDJ40323.1 - 3.2 7.3 12.4 5.6 6.5 12.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) SPX PF03105.19 CDJ40323.1 - 4.2 7.2 21.7 7.8 6.3 21.7 1.4 1 0 0 1 1 1 0 SPX domain Agenet PF05641.12 CDJ40324.1 - 0.043 14.3 0.0 0.33 11.4 0.0 2.0 2 0 0 2 2 2 0 Agenet domain SR-25 PF10500.9 CDJ40327.1 - 0.00045 19.9 6.7 0.00071 19.3 6.7 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.13 CDJ40327.1 - 0.0056 17.2 1.8 0.011 16.3 1.8 1.4 1 0 0 1 1 1 1 Secretin N-terminal domain Mannitol_dh_C PF08125.13 CDJ40327.1 - 0.01 15.4 0.0 0.029 13.8 0.0 1.8 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain AF-4 PF05110.13 CDJ40327.1 - 0.029 12.5 11.9 0.04 12.0 11.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PAP1 PF08601.10 CDJ40327.1 - 0.096 12.4 4.4 0.16 11.7 4.4 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 CCSAP PF15748.5 CDJ40328.1 - 0.052 13.7 24.0 0.054 13.7 24.0 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated AF-4 PF05110.13 CDJ40328.1 - 1.9 6.5 22.9 2.1 6.3 22.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NST1 PF13945.6 CDJ40328.1 - 1.9 8.6 27.1 2.3 8.3 27.1 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Strabismus PF06638.11 CDJ40328.1 - 4.1 5.9 12.6 4.7 5.7 12.6 1.0 1 0 0 1 1 1 0 Strabismus protein Lin-8 PF03353.15 CDJ40328.1 - 8.6 5.8 22.2 9.2 5.7 22.2 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF5427 PF10310.9 CDJ40328.1 - 9.2 5.1 24.1 10 5.0 24.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Toxin_ToxA PF11584.8 CDJ40329.1 - 0.009 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Proteinaceous host-selective toxin ToxA Ribosomal_60s PF00428.19 CDJ40329.1 - 0.048 14.3 2.0 0.093 13.3 2.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3446 PF11928.8 CDJ40330.1 - 0.33 11.3 18.9 1.7 9.0 5.1 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 CDJ40331.1 - 0.0044 16.7 3.3 0.0044 16.7 3.3 6.1 4 1 2 6 6 6 2 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ40332.1 - 1.3 8.6 17.8 1.7 8.2 17.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF5427 PF10310.9 CDJ40333.1 - 0.15 11.0 26.5 0.15 11.0 26.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Nop14 PF04147.12 CDJ40333.1 - 0.3 9.2 21.4 0.29 9.3 21.4 1.0 1 0 0 1 1 1 0 Nop14-like family SpoIIP PF07454.11 CDJ40333.1 - 0.4 10.1 23.2 0.4 10.1 23.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 CDJ40333.1 - 0.51 9.1 22.5 0.51 9.1 22.5 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DNA_pol_phi PF04931.13 CDJ40333.1 - 0.65 8.0 19.0 0.6 8.1 19.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi GNT-I PF03071.15 CDJ40333.1 - 0.68 8.6 10.7 0.66 8.7 10.7 1.0 1 0 0 1 1 1 0 GNT-I family CDC45 PF02724.14 CDJ40333.1 - 0.88 7.8 22.7 0.88 7.8 22.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 CDJ40333.1 - 1.8 6.6 19.4 1.7 6.6 19.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) EPL1 PF10513.9 CDJ40333.1 - 2.1 8.7 22.7 3.1 8.2 22.7 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Methyltransf_32 PF13679.6 CDJ40333.1 - 2.2 8.2 13.4 2.5 8.1 13.4 1.2 1 0 0 1 1 1 0 Methyltransferase domain MCM_bind PF09739.9 CDJ40333.1 - 2.9 6.2 19.1 2.9 6.2 19.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CCSAP PF15748.5 CDJ40333.1 - 3.6 7.7 26.3 3.7 7.7 26.3 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TRAP_alpha PF03896.16 CDJ40333.1 - 3.8 6.6 16.3 4.2 6.5 16.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.12 CDJ40333.1 - 4.3 6.7 26.0 4.4 6.6 26.0 1.0 1 0 0 1 1 1 0 SDA1 DDHD PF02862.17 CDJ40333.1 - 4.5 7.4 18.5 5.8 7.0 18.5 1.3 1 0 0 1 1 1 0 DDHD domain SLC12 PF03522.15 CDJ40333.1 - 4.7 6.1 21.2 4.7 6.1 21.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 CDJ40333.1 - 4.8 6.7 27.3 4.8 6.6 27.3 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 CDJ40333.1 - 4.9 5.8 28.5 5 5.8 28.5 1.0 1 0 0 1 1 1 0 Presenilin Slu7 PF11708.8 CDJ40333.1 - 5.2 6.7 24.2 5.2 6.7 24.2 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor RP-C_C PF11800.8 CDJ40333.1 - 5.2 7.1 20.4 5.4 7.1 20.4 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region NPR3 PF03666.13 CDJ40333.1 - 5.8 5.6 22.1 6 5.6 22.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2151 PF10221.9 CDJ40333.1 - 5.8 5.4 16.1 5.8 5.4 16.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator CLN3 PF02487.17 CDJ40333.1 - 5.9 5.8 17.6 5.8 5.8 17.6 1.0 1 0 0 1 1 1 0 CLN3 protein Dynamin_N PF00350.23 CDJ40333.1 - 6.3 6.8 12.8 6.7 6.7 12.8 1.2 1 0 0 1 1 1 0 Dynamin family Scs3p PF10261.9 CDJ40333.1 - 7.2 6.0 6.9 8.2 5.9 6.9 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Isy1 PF06246.12 CDJ40333.1 - 7.6 6.0 24.4 8 5.9 24.4 1.1 1 0 0 1 1 1 0 Isy1-like splicing family eIF-3_zeta PF05091.12 CDJ40333.1 - 7.6 5.4 24.9 7.8 5.4 24.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pex14_N PF04695.13 CDJ40333.1 - 8.3 7.1 27.6 11 6.7 27.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 CDJ40333.1 - 8.5 6.1 20.2 9.8 5.8 20.2 1.2 1 0 0 1 1 1 0 Connexin Tfb4 PF03850.14 CDJ40333.1 - 8.8 5.7 10.8 8.8 5.7 10.8 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 RR_TM4-6 PF06459.12 CDJ40333.1 - 9.1 6.0 31.3 10 5.9 31.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 CDJ40333.1 - 9.3 5.6 27.8 9.8 5.5 27.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ALMT PF11744.8 CDJ40333.1 - 9.6 4.9 19.5 10 4.8 19.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_S64 PF08192.11 CDJ40333.1 - 9.7 4.5 19.9 10 4.5 19.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 Pex14_N PF04695.13 CDJ40335.1 - 0.02 15.5 26.6 0.027 15.1 26.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2207 PF09972.9 CDJ40335.1 - 0.17 10.6 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CDC45 PF02724.14 CDJ40335.1 - 0.29 9.4 8.5 0.32 9.2 8.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 CDJ40335.1 - 0.31 10.4 16.1 0.37 10.1 16.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TCP PF03634.13 CDJ40335.1 - 0.48 11.0 14.8 0.6 10.7 14.8 1.1 1 0 0 1 1 1 0 TCP family transcription factor TAF4 PF05236.14 CDJ40335.1 - 0.58 9.9 17.3 0.81 9.4 17.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF2076 PF09849.9 CDJ40335.1 - 0.6 10.1 28.9 0.84 9.6 28.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) BAF1_ABF1 PF04684.13 CDJ40335.1 - 0.79 8.7 13.7 0.92 8.5 13.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4813 PF16072.5 CDJ40335.1 - 1.2 8.8 18.5 1.5 8.4 18.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) SOG2 PF10428.9 CDJ40335.1 - 1.2 8.3 19.5 1.4 8.0 19.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SelP_N PF04592.14 CDJ40335.1 - 1.2 8.4 13.5 1.4 8.2 13.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Nha1_C PF08619.10 CDJ40335.1 - 1.3 8.2 18.5 1.5 7.9 18.5 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus eIF-3_zeta PF05091.12 CDJ40335.1 - 1.3 7.9 13.3 1.5 7.7 13.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Mitofilin PF09731.9 CDJ40335.1 - 1.5 7.6 22.4 1.7 7.4 22.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Spc7_N PF15402.6 CDJ40335.1 - 1.6 6.9 19.5 1.9 6.7 19.5 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Lin-8 PF03353.15 CDJ40335.1 - 2 7.9 16.6 2.5 7.6 16.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Velvet PF11754.8 CDJ40335.1 - 2.6 7.9 16.9 3 7.7 16.9 1.1 1 0 0 1 1 1 0 Velvet factor TFIIA PF03153.13 CDJ40335.1 - 2.8 7.9 35.7 3.2 7.6 35.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4366 PF14283.6 CDJ40335.1 - 3 7.9 9.6 5.2 7.1 9.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) FAM60A PF15396.6 CDJ40335.1 - 3.9 7.4 11.9 5 7.1 11.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A GREB1 PF15782.5 CDJ40335.1 - 4.4 4.3 20.6 4.7 4.2 20.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4551 PF15087.6 CDJ40335.1 - 4.4 6.0 15.7 4.8 5.9 15.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PAT1 PF09770.9 CDJ40335.1 - 6.9 4.8 25.7 7.3 4.7 25.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF5427 PF10310.9 CDJ40335.1 - 7.2 5.4 19.8 8.1 5.3 19.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Endostatin PF06482.11 CDJ40335.1 - 8.1 5.8 16.5 9.5 5.6 16.5 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Peptidase_S64 PF08192.11 CDJ40335.1 - 8.7 4.7 11.5 10 4.5 11.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Spore_coat_CotO PF14153.6 CDJ40335.1 - 9.9 6.0 20.8 12 5.7 20.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Med3 PF11593.8 CDJ40337.1 - 0.056 12.6 13.5 0.065 12.4 13.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CRISPR_Cse2 PF09485.10 CDJ40337.1 - 0.076 13.5 3.6 0.086 13.4 3.6 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Cwf_Cwc_15 PF04889.12 CDJ40337.1 - 4.5 6.9 13.6 4.8 6.8 13.6 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_A21 PF03566.13 CDJ40337.1 - 4.6 5.4 10.5 5.7 5.1 10.5 1.1 1 0 0 1 1 1 0 Peptidase family A21 DUF2477 PF10631.9 CDJ40337.1 - 8.7 7.0 10.3 11 6.7 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) DUF4834 PF16118.5 CDJ40338.1 - 0.014 16.3 6.0 0.1 13.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 CDJ40338.1 - 0.03 14.0 0.9 0.29 10.8 0.0 2.5 3 0 0 3 3 3 0 FAM176 family KASH PF10541.9 CDJ40338.1 - 0.042 14.1 0.4 0.12 12.6 0.4 1.7 1 0 0 1 1 1 0 Nuclear envelope localisation domain EphA2_TM PF14575.6 CDJ40338.1 - 1.4 9.9 0.0 1.4 9.9 0.0 2.6 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Ly49 PF08391.10 CDJ40338.1 - 2 8.8 0.0 2 8.8 0.0 2.6 3 0 0 3 3 3 0 Ly49-like protein, N-terminal region V_ATPase_I PF01496.19 CDJ40338.1 - 4.6 5.0 4.2 0.66 7.8 0.2 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3682 PF12446.8 CDJ40340.1 - 0.007 16.8 16.8 0.007 16.8 16.8 4.7 3 2 1 4 4 4 1 Protein of unknown function (DUF3682) SR-25 PF10500.9 CDJ40340.1 - 0.017 14.7 38.2 0.18 11.4 17.2 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DDHD PF02862.17 CDJ40340.1 - 3.2 7.9 16.3 14 5.8 0.1 2.1 2 0 0 2 2 2 0 DDHD domain TCP PF03634.13 CDJ40340.1 - 5.1 7.6 25.1 7 7.2 1.8 2.1 2 0 0 2 2 2 0 TCP family transcription factor DNA_ligase_A_M PF01068.21 CDJ40341.1 - 6.8e-07 29.1 0.0 9.7e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DUF4333 PF14230.6 CDJ40341.1 - 0.082 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4333) KAR9 PF08580.10 CDJ40341.1 - 4.6 5.7 5.7 4.5 5.7 5.7 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 NUDE_C PF04880.13 CDJ40341.1 - 5 7.6 11.2 7 7.1 11.2 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region TFIIA PF03153.13 CDJ40341.1 - 8.1 6.3 15.2 10 6.0 15.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRORP PF16953.5 CDJ40342.1 - 8.1e-05 22.3 9.2 0.047 13.2 0.0 2.7 2 1 0 2 2 2 1 Protein-only RNase P TERB2 PF15101.6 CDJ40342.1 - 0.008 16.3 10.6 0.008 16.3 10.6 2.5 2 1 0 2 2 1 1 Telomere-associated protein TERB2 SPX PF03105.19 CDJ40342.1 - 0.015 15.3 15.1 0.02 14.8 15.1 1.1 1 0 0 1 1 1 0 SPX domain SpoIIP PF07454.11 CDJ40342.1 - 0.017 14.6 10.1 0.028 13.9 10.1 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Membralin PF09746.9 CDJ40342.1 - 0.02 14.0 5.2 0.032 13.3 5.2 1.3 1 0 0 1 1 1 0 Tumour-associated protein DUF4746 PF15928.5 CDJ40342.1 - 0.031 13.7 2.1 0.041 13.3 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4407 PF14362.6 CDJ40342.1 - 0.05 13.0 10.5 0.064 12.6 10.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3381 PF11861.8 CDJ40342.1 - 0.15 11.8 17.3 0.35 10.7 17.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) ABC2_membrane_2 PF12679.7 CDJ40342.1 - 0.25 10.6 0.2 0.21 10.8 0.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein CLN3 PF02487.17 CDJ40342.1 - 0.3 10.1 8.9 0.027 13.5 4.5 1.5 2 0 0 2 2 2 0 CLN3 protein Paf1 PF03985.13 CDJ40342.1 - 0.31 10.0 13.7 0.71 8.8 13.7 1.6 1 0 0 1 1 1 0 Paf1 DUF2828 PF11443.8 CDJ40342.1 - 0.33 9.0 11.5 0.52 8.3 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Peptidase_U57 PF05582.12 CDJ40342.1 - 0.36 10.1 7.2 0.53 9.5 7.2 1.2 1 0 0 1 1 1 0 YabG peptidase U57 V_ATPase_I PF01496.19 CDJ40342.1 - 0.48 8.3 12.6 0.71 7.7 12.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SR-25 PF10500.9 CDJ40342.1 - 0.78 9.3 31.8 1.4 8.4 4.1 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein eIF-3_zeta PF05091.12 CDJ40342.1 - 1.2 8.0 19.9 1.7 7.5 19.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RNase_Zc3h12a PF11977.8 CDJ40342.1 - 1.3 8.7 0.0 1.3 8.7 0.0 2.4 3 0 0 3 3 1 0 Zc3h12a-like Ribonuclease NYN domain Neur_chan_memb PF02932.16 CDJ40342.1 - 1.6 8.8 14.0 3.4 7.6 9.6 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ40342.1 - 1.7 8.6 42.7 3.4 7.6 42.7 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF853 PF05872.12 CDJ40342.1 - 1.7 7.2 11.1 2.4 6.7 11.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Pkinase_fungal PF17667.1 CDJ40342.1 - 1.8 7.2 11.3 0.29 9.9 3.8 2.0 2 0 0 2 2 2 0 Fungal protein kinase DUF4770 PF15994.5 CDJ40342.1 - 2.1 8.6 15.1 1.6 8.9 13.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF913 PF06025.12 CDJ40342.1 - 2.3 7.1 9.7 0.91 8.4 5.1 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Cellulose_synt PF03552.14 CDJ40342.1 - 2.5 6.5 3.9 3.5 6.0 3.9 1.2 1 0 0 1 1 1 0 Cellulose synthase FAM60A PF15396.6 CDJ40342.1 - 2.6 8.0 13.9 1.7 8.6 7.7 2.1 2 0 0 2 2 2 0 Protein Family FAM60A SID-1_RNA_chan PF13965.6 CDJ40342.1 - 2.7 6.3 5.8 4.6 5.5 5.8 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Folliculin PF11704.8 CDJ40342.1 - 2.7 7.8 16.9 11 5.9 0.2 2.2 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Gti1_Pac2 PF09729.9 CDJ40342.1 - 3.1 7.8 16.4 1.5 8.9 9.8 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family DUF4175 PF13779.6 CDJ40342.1 - 3.5 5.4 37.4 5.6 4.7 37.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CPSF100_C PF13299.6 CDJ40342.1 - 3.6 7.8 15.7 0.21 11.8 9.3 2.0 2 1 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SURF6 PF04935.12 CDJ40342.1 - 3.6 7.3 26.9 0.046 13.5 18.8 1.8 2 1 0 2 2 2 0 Surfeit locus protein 6 DUF4050 PF13259.6 CDJ40342.1 - 4.7 7.5 18.9 9.5 6.5 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Apc15p PF05841.11 CDJ40342.1 - 5.8 7.7 24.8 0.92 10.3 17.2 2.3 2 0 0 2 2 2 0 Apc15p protein Serinc PF03348.15 CDJ40342.1 - 6.1 5.7 8.2 9.7 5.0 8.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) XRN_M PF17846.1 CDJ40342.1 - 6.3 5.6 10.6 10 4.9 10.6 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Peroxin-13_N PF04088.13 CDJ40342.1 - 6.3 7.1 9.2 1.3 9.3 5.7 1.7 2 0 0 2 2 1 0 Peroxin 13, N-terminal region AIF_C PF14721.6 CDJ40342.1 - 6.6 7.1 12.8 0.091 13.1 4.5 2.1 2 1 1 3 3 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Asparaginase_2 PF01112.18 CDJ40342.1 - 6.8 5.6 7.4 10 5.1 7.4 1.2 1 0 0 1 1 1 0 Asparaginase RR_TM4-6 PF06459.12 CDJ40342.1 - 7.1 6.4 16.0 2.2 8.0 12.9 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ40342.1 - 7.3 5.5 17.6 1.6 7.6 12.9 1.8 2 0 0 2 2 2 0 Solute carrier family 12 MCU PF04678.13 CDJ40342.1 - 8 6.5 11.2 14 5.7 11.2 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter NEMP PF10225.9 CDJ40342.1 - 9.3 5.8 6.8 16 5.1 6.8 1.4 1 0 0 1 1 1 0 NEMP family FAM176 PF14851.6 CDJ40342.1 - 10 5.8 14.0 0.42 10.3 5.4 2.3 2 1 0 2 2 2 0 FAM176 family DUF1180 PF06679.12 CDJ40343.1 - 0.65 10.4 9.3 0.99 9.8 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF1957 PF09210.11 CDJ40343.1 - 5.1 7.6 6.4 2.4 8.6 1.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1957) FYVE PF01363.21 CDJ40344.1 - 0.63 10.2 11.3 1.7 8.8 8.8 2.6 2 1 0 2 2 2 0 FYVE zinc finger Prim_Zn_Ribbon PF08273.12 CDJ40344.1 - 3.1 8.2 12.1 2.8 8.3 8.6 2.7 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase Apt1 PF10351.9 CDJ40345.1 - 0.015 14.2 5.0 0.023 13.6 5.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Secretin_N_2 PF07655.13 CDJ40345.1 - 0.072 13.6 13.7 0.8 10.3 7.5 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain MA3 PF02847.17 CDJ40346.1 - 3.6e-17 62.4 4.0 9.6e-17 61.0 4.0 1.8 1 0 0 1 1 1 1 MA3 domain DUF5523 PF17661.1 CDJ40346.1 - 0.45 10.2 5.2 0.11 12.1 1.8 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5523) RskA PF10099.9 CDJ40346.1 - 0.79 10.0 10.5 0.056 13.7 5.7 1.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF4692 PF15763.5 CDJ40346.1 - 2.6 8.5 7.1 7.1 7.1 1.5 2.2 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) SR-25 PF10500.9 CDJ40346.1 - 8.1 6.0 14.3 12 5.4 9.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SNARE PF05739.19 CDJ40348.1 - 1 9.4 2.5 2.1 8.4 2.5 1.4 1 0 0 1 1 1 0 SNARE domain DUF3597 PF12200.8 CDJ40348.1 - 9.6 6.8 31.4 0.11 13.0 1.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3597) SR-25 PF10500.9 CDJ40349.1 - 7.4e-06 25.7 30.2 7.4e-06 25.7 30.2 3.6 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein KCNQ2_u3 PF16642.5 CDJ40349.1 - 0.0059 17.6 2.6 0.0059 17.6 2.6 7.5 5 4 0 5 5 5 1 Unstructured region on Potassium channel subunit alpha KvLQT2 TCP PF03634.13 CDJ40349.1 - 0.85 10.2 45.0 0.12 12.9 2.1 4.2 4 0 0 4 4 4 0 TCP family transcription factor CDC45 PF02724.14 CDJ40349.1 - 8.5 4.5 33.1 0.25 9.6 2.5 2.2 2 0 0 2 2 2 0 CDC45-like protein AAA PF00004.29 CDJ40353.1 - 6.3e-07 29.9 0.0 9.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CDJ40353.1 - 0.006 16.7 0.0 0.008 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 CDJ40353.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein RPN7 PF10602.9 CDJ40355.1 - 3.7e-45 153.7 0.5 5.4e-45 153.2 0.5 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CDJ40355.1 - 1.2e-15 57.9 0.0 3.3e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 PCI domain HTH_11 PF08279.12 CDJ40355.1 - 0.091 12.7 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 HTH domain Suf PF05843.14 CDJ40356.1 - 0.011 15.8 10.9 0.013 15.5 10.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2722 PF10846.8 CDJ40356.1 - 0.019 13.9 23.0 0.024 13.6 23.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF913 PF06025.12 CDJ40356.1 - 0.033 13.2 7.0 0.038 13.0 7.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Roughex PF06020.11 CDJ40356.1 - 0.056 12.5 12.3 0.058 12.5 12.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein SpoIIP PF07454.11 CDJ40356.1 - 0.068 12.6 10.0 0.081 12.4 10.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Folliculin PF11704.8 CDJ40356.1 - 0.11 12.3 13.1 0.15 11.9 13.1 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport MecA PF05389.12 CDJ40356.1 - 0.13 11.9 8.2 0.14 11.7 8.2 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DDHD PF02862.17 CDJ40356.1 - 0.17 12.0 11.4 0.19 11.8 11.4 1.1 1 0 0 1 1 1 0 DDHD domain Seryl_tRNA_N PF02403.22 CDJ40356.1 - 0.18 12.1 25.1 0.14 12.4 1.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3371 PF11851.8 CDJ40356.1 - 0.18 12.9 11.2 0.24 12.5 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Band_3_cyto PF07565.13 CDJ40356.1 - 0.18 11.6 10.7 0.23 11.3 10.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MMR1 PF08505.10 CDJ40356.1 - 0.2 11.9 15.5 0.23 11.7 15.5 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF3408 PF11888.8 CDJ40356.1 - 0.21 11.7 11.9 0.25 11.5 11.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) FAM176 PF14851.6 CDJ40356.1 - 0.32 10.7 8.2 0.42 10.3 8.2 1.2 1 0 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.12 CDJ40356.1 - 0.33 10.7 12.6 0.38 10.5 12.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLY PF12485.8 CDJ40356.1 - 0.39 11.4 9.4 0.48 11.1 9.4 1.1 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Med15 PF09606.10 CDJ40356.1 - 0.39 9.3 26.6 0.46 9.1 26.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4746 PF15928.5 CDJ40356.1 - 0.4 10.0 10.9 0.47 9.8 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF572 PF04502.13 CDJ40356.1 - 0.42 10.2 14.0 0.55 9.8 14.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) YL1 PF05764.13 CDJ40356.1 - 0.44 10.6 26.8 0.51 10.4 26.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Paf1 PF03985.13 CDJ40356.1 - 0.46 9.4 20.6 0.54 9.2 20.6 1.0 1 0 0 1 1 1 0 Paf1 TCP PF03634.13 CDJ40356.1 - 0.49 11.0 21.2 0.64 10.6 21.2 1.1 1 0 0 1 1 1 0 TCP family transcription factor Neur_chan_memb PF02932.16 CDJ40356.1 - 0.49 10.4 10.3 0.57 10.2 10.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2795 PF11387.8 CDJ40356.1 - 0.5 10.6 2.8 0.4 10.9 0.4 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF2795) SPT16 PF08644.11 CDJ40356.1 - 0.52 10.5 8.7 0.61 10.3 8.7 1.2 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF2052 PF09747.9 CDJ40356.1 - 0.52 10.4 16.3 0.67 10.0 16.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CCDC53 PF10152.9 CDJ40356.1 - 0.54 10.7 13.6 0.65 10.4 13.6 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Hydin_ADK PF17213.3 CDJ40356.1 - 0.57 10.4 10.8 0.71 10.1 10.8 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain TERB2 PF15101.6 CDJ40356.1 - 0.6 10.1 17.1 0.79 9.7 17.1 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Connexin PF00029.19 CDJ40356.1 - 0.67 9.7 7.3 0.81 9.4 7.3 1.2 1 0 0 1 1 1 0 Connexin Gti1_Pac2 PF09729.9 CDJ40356.1 - 0.73 9.9 10.7 0.92 9.6 10.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family EPL1 PF10513.9 CDJ40356.1 - 0.82 10.0 14.2 1.1 9.6 14.2 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like eIF-3_zeta PF05091.12 CDJ40356.1 - 0.9 8.4 15.6 0.93 8.4 15.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 CDJ40356.1 - 0.94 8.4 12.4 1.1 8.3 12.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 MTBP_C PF14920.6 CDJ40356.1 - 1 9.1 15.4 1.2 8.8 15.4 1.1 1 0 0 1 1 1 0 MDM2-binding GREB1 PF15782.5 CDJ40356.1 - 1.3 6.1 11.0 1.4 6.0 11.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 CDJ40356.1 - 1.3 7.6 11.5 1.4 7.5 11.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ESM4 PF15952.5 CDJ40356.1 - 1.4 9.4 20.7 1.7 9.0 20.7 1.1 1 0 0 1 1 1 0 Enhancer of split M4 family ALMT PF11744.8 CDJ40356.1 - 1.4 7.6 14.0 1.6 7.4 14.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 CDJ40356.1 - 1.4 7.6 17.7 1.6 7.4 17.7 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CDJ40356.1 - 1.5 8.0 2.7 1.6 7.8 2.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.13 CDJ40356.1 - 1.6 8.6 32.5 2 8.3 32.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.8 CDJ40356.1 - 1.6 7.8 27.5 1.8 7.6 27.5 1.1 1 0 0 1 1 1 0 SprA-related family PA26 PF04636.13 CDJ40356.1 - 1.7 7.4 10.7 1.9 7.3 10.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Het-C PF07217.11 CDJ40356.1 - 1.7 7.0 7.8 1.8 7.0 7.8 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF3306 PF11748.8 CDJ40356.1 - 1.9 9.4 19.3 0.65 10.9 14.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) OATP PF03137.20 CDJ40356.1 - 2 6.6 5.4 2.1 6.5 5.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SET PF00856.28 CDJ40356.1 - 2 8.8 4.7 2.6 8.4 4.7 1.3 1 0 0 1 1 1 0 SET domain ATAD4 PF15321.6 CDJ40356.1 - 2.3 9.6 14.2 1.6 10.1 12.4 1.6 2 0 0 2 2 1 0 ATPase family AAA domain containing 4 CSG2 PF16965.5 CDJ40356.1 - 2.3 7.1 5.8 2.6 6.9 5.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator GNAT_acetyltr_2 PF13718.6 CDJ40356.1 - 2.4 7.5 9.3 3.1 7.1 9.3 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 MCD PF05292.11 CDJ40356.1 - 2.4 7.6 9.4 2.9 7.4 8.9 1.3 1 1 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain DUF4175 PF13779.6 CDJ40356.1 - 2.6 5.8 38.5 3.3 5.5 38.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ctr PF04145.15 CDJ40356.1 - 2.6 8.6 8.7 3.7 8.1 8.7 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Ureide_permease PF07168.11 CDJ40356.1 - 2.7 6.7 4.7 2.9 6.5 4.7 1.2 1 0 0 1 1 1 0 Ureide permease FAM60A PF15396.6 CDJ40356.1 - 2.8 7.9 10.1 3.1 7.7 10.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Vfa1 PF08432.10 CDJ40356.1 - 2.8 8.2 18.4 3.4 8.0 18.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Plasmodium_Vir PF05795.11 CDJ40356.1 - 2.9 7.2 7.2 2.9 7.2 7.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GBP_C PF02841.14 CDJ40356.1 - 3 7.2 25.3 3.6 6.9 25.3 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain V_ATPase_I PF01496.19 CDJ40356.1 - 3.1 5.6 14.3 3.4 5.5 14.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1980 PF09323.10 CDJ40356.1 - 3.2 7.6 5.9 3.4 7.5 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) FPN1 PF06963.12 CDJ40356.1 - 3.3 6.2 4.7 3.8 6.0 4.7 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Hid1 PF12722.7 CDJ40356.1 - 3.3 5.7 12.8 3.4 5.7 12.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EOS1 PF12326.8 CDJ40356.1 - 3.4 7.6 5.6 3.8 7.4 5.6 1.2 1 0 0 1 1 1 0 N-glycosylation protein MPM1 PF17234.2 CDJ40356.1 - 4 7.7 14.2 6 7.1 14.2 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Peptidase_S64 PF08192.11 CDJ40356.1 - 4.2 5.7 10.8 4.7 5.6 10.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF3381 PF11861.8 CDJ40356.1 - 4.2 7.1 26.1 0.91 9.3 22.8 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF3381) XRN_M PF17846.1 CDJ40356.1 - 4.3 6.2 12.1 5.1 5.9 12.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain PAT1 PF09770.9 CDJ40356.1 - 4.4 5.5 23.8 5 5.3 23.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Membralin PF09746.9 CDJ40356.1 - 4.4 6.2 7.9 5.1 6.0 7.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein ATG22 PF11700.8 CDJ40356.1 - 4.5 5.8 5.9 5.6 5.5 5.9 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DNApol_Exo PF18136.1 CDJ40356.1 - 4.6 6.3 10.1 5.7 6.0 10.1 1.1 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain UPF0565 PF10561.9 CDJ40356.1 - 4.8 6.3 8.4 5.4 6.1 8.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Peptidase_U57 PF05582.12 CDJ40356.1 - 5.7 6.1 9.8 6.4 5.9 9.8 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Peptidase_S46 PF10459.9 CDJ40356.1 - 5.8 5.4 15.2 7 5.1 15.2 1.0 1 0 0 1 1 1 0 Peptidase S46 ACOX PF01756.19 CDJ40356.1 - 5.9 6.4 13.3 8.6 5.9 12.8 1.5 1 1 0 1 1 1 0 Acyl-CoA oxidase XAP5 PF04921.14 CDJ40356.1 - 6.1 6.6 12.8 7.8 6.3 12.8 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Sec62 PF03839.16 CDJ40356.1 - 6.1 6.3 12.7 8.1 5.9 12.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PepSY_TM PF03929.16 CDJ40356.1 - 6.2 6.4 7.0 6.7 6.3 7.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region CLN3 PF02487.17 CDJ40356.1 - 6.2 5.7 13.0 8.1 5.4 13.0 1.1 1 0 0 1 1 1 0 CLN3 protein Folate_carrier PF01770.18 CDJ40356.1 - 6.3 5.4 7.1 7.1 5.3 7.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF2828 PF11443.8 CDJ40356.1 - 6.4 4.7 14.6 7.2 4.6 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) IHABP4_N PF16174.5 CDJ40356.1 - 6.5 7.3 22.7 9 6.9 22.7 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Asp-B-Hydro_N PF05279.11 CDJ40356.1 - 6.9 6.7 13.3 8.6 6.3 13.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TMEM51 PF15345.6 CDJ40356.1 - 7.2 6.4 16.2 10 5.9 16.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 CENP-O PF09496.10 CDJ40356.1 - 7.3 6.5 14.0 9 6.2 14.0 1.2 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component F-protein PF00469.20 CDJ40356.1 - 7.4 6.1 12.8 9.8 5.7 12.8 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef SID-1_RNA_chan PF13965.6 CDJ40356.1 - 8 4.7 7.2 8.8 4.6 7.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF702 PF05142.12 CDJ40356.1 - 8.2 6.9 14.0 13 6.2 14.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Pex14_N PF04695.13 CDJ40356.1 - 8.5 7.0 23.4 15 6.2 23.4 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peroxin-13_N PF04088.13 CDJ40356.1 - 8.8 6.6 11.3 15 5.9 11.3 1.5 1 1 0 1 1 1 0 Peroxin 13, N-terminal region MRNIP PF15749.5 CDJ40356.1 - 9.8 6.9 22.4 18 6.1 22.4 1.6 1 1 0 1 1 1 0 MRN-interacting protein Serinc PF03348.15 CDJ40356.1 - 9.9 5.0 7.0 9.5 5.0 7.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Myb_DNA-binding PF00249.31 CDJ40357.1 - 2.6e-05 24.3 0.0 5.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ40357.1 - 0.00019 21.6 0.3 0.00057 20.1 0.3 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DGF-1_C PF11040.8 CDJ40357.1 - 0.011 15.7 0.7 0.011 15.7 0.7 2.8 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Rap1_C PF11626.8 CDJ40357.1 - 0.034 14.2 0.1 0.094 12.8 0.1 1.8 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain IMUP PF15761.5 CDJ40357.1 - 2.2 9.0 26.8 0.051 14.3 4.7 3.0 3 0 0 3 3 3 0 Immortalisation up-regulated protein Macoilin PF09726.9 CDJ40360.1 - 0.025 13.2 13.4 0.051 12.2 13.4 1.4 1 0 0 1 1 1 0 Macoilin family HEAT PF02985.22 CDJ40360.1 - 0.078 13.3 15.3 0.47 10.9 0.3 6.3 5 0 0 5 5 5 0 HEAT repeat NOZZLE PF08744.10 CDJ40360.1 - 0.35 10.3 2.7 0.18 11.3 0.2 1.8 2 0 0 2 2 2 0 Plant transcription factor NOZZLE IZUMO PF15005.6 CDJ40360.1 - 0.61 10.6 10.8 0.35 11.4 5.5 2.6 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Spt20 PF12090.8 CDJ40361.1 - 3.7 7.1 10.4 2.6 7.6 3.7 2.2 2 0 0 2 2 2 0 Spt20 family CRAL_TRIO_2 PF13716.6 CDJ40363.1 - 2.9e-21 76.1 0.1 3.9e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CDJ40363.1 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 CRAL/TRIO domain RhoGAP PF00620.27 CDJ40363.1 - 0.1 12.4 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 RhoGAP domain DUF3391 PF11871.8 CDJ40363.1 - 9.4 6.8 8.0 1.4e+02 3.0 8.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) SDA1 PF05285.12 CDJ40364.1 - 0.12 11.8 9.3 0.16 11.4 9.3 1.2 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 CDJ40364.1 - 2 7.6 3.7 2.1 7.5 3.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S49_N PF08496.10 CDJ40364.1 - 5.3 7.1 7.4 9.9 6.2 7.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.12 CDJ40364.1 - 7.9 6.2 14.8 0.69 9.7 10.6 1.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Pex14_N PF04695.13 CDJ40365.1 - 1.6 9.3 31.0 0.13 12.9 15.2 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CCSAP PF15748.5 CDJ40365.1 - 3.4 7.8 26.6 2.1 8.4 4.3 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Pkinase PF00069.25 CDJ40366.1 - 3.1e-13 49.7 9.4 1.3e-11 44.4 0.1 3.8 3 2 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ40366.1 - 0.00015 21.2 0.9 0.00022 20.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ40366.1 - 0.012 14.6 0.1 0.012 14.6 0.1 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Peptidase_C92 PF05708.12 CDJ40367.1 - 1.4e-07 31.7 0.6 3.3e-06 27.3 0.0 3.0 2 1 0 2 2 2 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family PAT1 PF09770.9 CDJ40368.1 - 3.4 5.8 21.0 4.2 5.5 21.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF702 PF05142.12 CDJ40368.1 - 3.9 7.9 13.8 13 6.3 13.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF702) Ribosomal_60s PF00428.19 CDJ40369.1 - 1.3 9.7 9.9 2.3 8.9 9.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein SUIM_assoc PF16619.5 CDJ40370.1 - 0.0045 17.0 0.0 0.0045 17.0 0.0 7.6 2 2 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 CDJ40370.1 - 0.03 13.1 35.1 0.093 11.5 32.1 2.1 2 0 0 2 2 2 0 Presenilin AAA_11 PF13086.6 CDJ40370.1 - 0.56 9.9 30.0 11 5.7 29.9 2.1 2 0 0 2 2 2 0 AAA domain Sporozoite_P67 PF05642.11 CDJ40370.1 - 0.8 7.7 16.3 1.4 6.9 16.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Caldesmon PF02029.15 CDJ40370.1 - 1.1 8.0 38.0 0.29 9.8 32.2 2.1 2 0 0 2 2 2 0 Caldesmon eIF-3_zeta PF05091.12 CDJ40370.1 - 1.3 8.0 34.1 0.13 11.3 25.9 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HCO3_cotransp PF00955.21 CDJ40370.1 - 1.6 7.5 10.9 2.9 6.6 10.9 1.3 1 0 0 1 1 1 0 HCO3- transporter family DUF2052 PF09747.9 CDJ40370.1 - 2.8 8.0 41.7 4.2 7.5 34.6 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 CDJ40370.1 - 3.3 5.9 32.9 0.012 13.9 23.4 1.6 2 0 0 2 2 2 0 CDC45-like protein Exonuc_VII_L PF02601.15 CDJ40370.1 - 3.7 7.0 32.5 23 4.4 0.0 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit PCEMA1 PF07418.11 CDJ40370.1 - 8.5 5.8 16.7 0.26 10.8 10.4 1.6 2 0 0 2 2 2 0 Acidic phosphoprotein precursor PCEMA1 DUF4614 PF15391.6 CDJ40371.1 - 0.16 11.9 15.2 0.25 11.3 15.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) PRP38_assoc PF12871.7 CDJ40371.1 - 0.61 10.7 28.9 1.3 9.7 28.9 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Apt1 PF10351.9 CDJ40371.1 - 0.71 8.7 10.7 0.76 8.6 10.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ40371.1 - 1.9 7.2 9.9 2.3 6.9 9.9 1.3 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ40371.1 - 2.1 7.2 8.2 3.1 6.7 8.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NPR3 PF03666.13 CDJ40371.1 - 2.4 6.9 12.0 2.8 6.6 12.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.16 CDJ40371.1 - 2.4 8.1 5.3 2.8 7.9 5.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EBP50_C PF09007.11 CDJ40372.1 - 8.4 7.4 16.6 9.7 7.2 16.6 1.2 1 0 0 1 1 1 0 EBP50, C-terminal PPR_2 PF13041.6 CDJ40373.1 - 1.2e-16 60.6 0.0 3e-08 33.7 0.0 3.8 3 0 0 3 3 3 3 PPR repeat family PPR_long PF17177.4 CDJ40373.1 - 1.1e-15 57.5 8.7 1.3e-07 31.2 3.7 2.7 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CDJ40373.1 - 7.7e-15 54.7 0.0 0.00017 21.6 0.0 4.3 2 1 2 4 4 4 4 Pentatricopeptide repeat domain PPR PF01535.20 CDJ40373.1 - 3.2e-08 33.3 0.3 0.15 12.4 0.0 4.9 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.7 CDJ40373.1 - 5.6e-07 29.2 0.0 1.5 8.6 0.0 5.1 5 0 0 5 5 5 2 PPR repeat Auxin_canalis PF05703.11 CDJ40374.1 - 0.0026 17.8 6.7 0.0026 17.8 6.7 4.9 3 1 1 4 4 4 1 Auxin canalisation CCDC24 PF15669.5 CDJ40374.1 - 0.0059 16.5 5.6 0.0059 16.5 5.6 4.2 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 24 family DUF2852 PF11014.8 CDJ40374.1 - 0.082 13.1 2.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) RIFIN PF02009.16 CDJ40374.1 - 6.1 6.6 11.3 0.088 12.7 0.2 2.5 2 0 0 2 2 2 0 Rifin Cpn60_TCP1 PF00118.24 CDJ40375.1 - 2.7e-71 240.7 0.6 4.2e-53 180.7 0.0 3.0 1 1 2 3 3 3 3 TCP-1/cpn60 chaperonin family Herpes_US9 PF06072.11 CDJ40378.1 - 0.14 12.0 0.3 0.22 11.4 0.3 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF2116 PF09889.9 CDJ40378.1 - 2.2 8.3 4.9 0.79 9.8 2.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Mcm10 PF09332.11 CDJ40379.1 - 1.2 8.5 11.3 1.7 8.0 11.3 1.1 1 0 0 1 1 1 0 Mcm10 replication factor YL1 PF05764.13 CDJ40380.1 - 0.066 13.3 26.9 0.081 13.0 26.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein BAF1_ABF1 PF04684.13 CDJ40380.1 - 0.95 8.4 22.2 0.99 8.4 22.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Dehydrin PF00257.19 CDJ40380.1 - 0.98 10.0 20.7 0.064 13.8 14.1 1.9 1 1 1 2 2 2 0 Dehydrin CDC45 PF02724.14 CDJ40380.1 - 2 6.6 23.0 2.5 6.3 23.0 1.1 1 0 0 1 1 1 0 CDC45-like protein XRCC4 PF06632.12 CDJ40380.1 - 2.5 6.9 27.8 2.9 6.7 27.8 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RAB3GAP2_N PF14655.6 CDJ40381.1 - 0.074 12.3 1.4 0.12 11.6 1.4 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2722 PF10846.8 CDJ40383.1 - 1.8e-05 23.9 9.0 2.2e-05 23.6 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ40383.1 - 0.00014 22.0 12.3 0.00016 21.8 12.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ40383.1 - 0.0018 17.1 11.5 0.0018 17.1 11.5 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ndc1_Nup PF09531.10 CDJ40383.1 - 0.1 11.3 4.9 0.12 11.0 4.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ40383.1 - 0.12 11.1 2.3 0.16 10.7 2.3 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CDJ40383.1 - 0.13 12.9 10.8 0.25 12.0 8.2 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Activator_LAG-3 PF11498.8 CDJ40383.1 - 0.31 10.0 26.1 0.53 9.2 26.1 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4175 PF13779.6 CDJ40383.1 - 0.32 8.8 16.4 0.37 8.7 16.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF5336 PF17270.2 CDJ40383.1 - 0.37 10.4 6.1 0.52 9.9 6.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Suf PF05843.14 CDJ40383.1 - 0.64 10.0 12.8 0.26 11.3 9.8 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3043 PF11241.8 CDJ40383.1 - 0.94 9.5 4.8 4 7.5 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Protamine_P2 PF00841.19 CDJ40384.1 - 0.026 15.0 13.4 0.051 14.0 13.4 1.5 1 0 0 1 1 1 0 Sperm histone P2 Spt20 PF12090.8 CDJ40384.1 - 0.24 11.0 7.5 0.36 10.4 7.5 1.2 1 0 0 1 1 1 0 Spt20 family Conotoxin PF02950.17 CDJ40384.1 - 0.34 11.9 2.4 1.5 9.9 2.4 2.2 1 0 0 1 1 1 0 Conotoxin CENP-O PF09496.10 CDJ40384.1 - 0.89 9.5 3.6 0.21 11.5 0.4 1.5 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component TFIIA PF03153.13 CDJ40384.1 - 6.8 6.6 11.1 3.8 7.4 7.5 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ40385.1 - 0.008 16.5 1.6 0.008 16.5 1.6 1.9 2 1 0 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ40385.1 - 0.67 9.9 10.7 0.4 10.6 5.2 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ40386.1 - 0.039 14.3 6.5 0.045 14.0 6.5 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA ACP53EA PF06313.11 CDJ40386.1 - 0.083 13.1 0.2 0.1 12.8 0.2 1.0 1 0 0 1 1 1 0 Drosophila ACP53EA protein SR-25 PF10500.9 CDJ40386.1 - 0.089 12.4 10.6 0.1 12.2 10.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein R_equi_Vir PF05526.11 CDJ40386.1 - 2.8 7.7 7.9 3.1 7.6 7.9 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein MSP1_C PF07462.11 CDJ40386.1 - 6.1 5.4 6.5 6.5 5.3 6.5 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pex14_N PF04695.13 CDJ40386.1 - 8.3 7.0 14.1 9.2 6.9 14.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Collagen PF01391.18 CDJ40387.1 - 0.00025 20.7 16.0 0.00025 20.7 16.0 3.7 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) U1snRNP70_N PF12220.8 CDJ40387.1 - 3.8 8.2 8.7 2.1 9.0 0.8 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SRP_TPR_like PF17004.5 CDJ40389.1 - 8.5e-07 29.0 1.6 8.5e-07 29.0 1.6 2.1 2 1 0 2 2 2 1 Putative TPR-like repeat TPR_14 PF13428.6 CDJ40389.1 - 0.00048 20.7 24.5 0.75 10.8 0.1 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ40389.1 - 0.00089 19.7 38.5 1.6 9.3 3.7 6.7 2 2 5 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ40389.1 - 0.0035 17.4 17.6 1.1 9.5 1.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ40389.1 - 0.0044 17.2 4.3 0.0044 17.2 4.3 4.0 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDJ40389.1 - 0.0071 16.6 32.3 0.026 14.8 6.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat PPR PF01535.20 CDJ40389.1 - 0.015 15.5 0.0 6.1 7.3 0.0 3.6 4 0 0 4 4 4 0 PPR repeat NARP1 PF12569.8 CDJ40389.1 - 0.033 13.1 0.6 0.033 13.1 0.6 2.9 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 CDJ40389.1 - 0.14 12.3 18.1 2.3 8.4 0.2 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ40389.1 - 0.51 11.1 21.4 39 5.2 0.7 6.8 5 1 1 6 6 6 0 Tetratricopeptide repeat HflK_N PF12221.8 CDJ40389.1 - 2.1 8.4 5.5 0.44 10.6 0.2 2.2 2 0 0 2 2 2 0 Bacterial membrane protein N terminal PGAP1 PF07819.13 CDJ40390.1 - 5.2e-07 29.6 0.0 9.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Nab1 PF04902.12 CDJ40390.1 - 0.0085 16.5 1.0 0.025 15.0 1.0 1.7 1 0 0 1 1 1 1 Conserved region in Nab1 DUF676 PF05057.14 CDJ40390.1 - 0.025 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AF-4 PF05110.13 CDJ40390.1 - 3.2 5.7 16.5 0.042 12.0 8.6 1.7 2 0 0 2 2 2 0 AF-4 proto-oncoprotein DUF572 PF04502.13 CDJ40391.1 - 9.7e-38 130.6 9.9 9.7e-38 130.6 9.9 3.0 2 2 0 2 2 2 1 Family of unknown function (DUF572) Atx10homo_assoc PF09759.9 CDJ40391.1 - 0.0029 17.6 0.0 0.0029 17.6 0.0 3.3 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain DUF866 PF05907.13 CDJ40391.1 - 0.13 12.2 2.8 0.09 12.7 0.3 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) TFIIA PF03153.13 CDJ40393.1 - 0.0005 20.2 28.3 0.00064 19.8 28.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CCSAP PF15748.5 CDJ40393.1 - 0.0065 16.7 17.8 0.013 15.7 17.8 1.5 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated CDC45 PF02724.14 CDJ40393.1 - 0.011 14.0 9.5 0.013 13.9 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RAP1 PF07218.11 CDJ40393.1 - 0.051 11.9 0.6 0.072 11.4 0.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DDHD PF02862.17 CDJ40393.1 - 0.095 12.8 8.0 0.12 12.5 8.0 1.4 1 0 0 1 1 1 0 DDHD domain TCP PF03634.13 CDJ40393.1 - 0.12 12.9 14.9 0.026 15.1 11.0 1.9 2 0 0 2 2 2 0 TCP family transcription factor Dynamin_N PF00350.23 CDJ40393.1 - 0.17 11.9 2.7 0.26 11.3 2.7 1.2 1 0 0 1 1 1 0 Dynamin family RR_TM4-6 PF06459.12 CDJ40393.1 - 0.24 11.2 15.9 0.32 10.8 15.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S15 PF02129.18 CDJ40393.1 - 0.27 10.8 9.8 0.39 10.3 9.8 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hamartin PF04388.12 CDJ40393.1 - 0.37 9.4 18.8 0.47 9.1 18.8 1.1 1 0 0 1 1 1 0 Hamartin protein MMR1 PF08505.10 CDJ40393.1 - 0.49 10.6 16.9 0.79 10.0 16.9 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Exonuc_VII_L PF02601.15 CDJ40393.1 - 1.1 8.7 15.2 1.3 8.5 15.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lin-8 PF03353.15 CDJ40393.1 - 1.1 8.7 19.9 0.58 9.7 17.3 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Pal1 PF08316.11 CDJ40393.1 - 1.1 10.0 6.7 2 9.2 6.7 1.4 1 0 0 1 1 1 0 Pal1 cell morphology protein Presenilin PF01080.17 CDJ40393.1 - 1.2 7.8 19.1 1.6 7.4 19.1 1.2 1 0 0 1 1 1 0 Presenilin SprA-related PF12118.8 CDJ40393.1 - 1.2 8.2 28.4 2.1 7.4 28.4 1.3 1 0 0 1 1 1 0 SprA-related family CobT PF06213.12 CDJ40393.1 - 1.3 8.4 20.7 1.7 8.0 20.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIP PF07454.11 CDJ40393.1 - 1.3 8.4 13.5 1.7 8.0 13.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ40393.1 - 1.6 7.6 16.8 1.9 7.3 16.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ribosomal_60s PF00428.19 CDJ40393.1 - 1.8 9.2 6.6 4.4 7.9 6.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein PAT1 PF09770.9 CDJ40393.1 - 2.4 6.3 27.8 3.2 5.9 27.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EOS1 PF12326.8 CDJ40393.1 - 2.6 8.0 4.7 4.7 7.1 4.7 1.6 1 0 0 1 1 1 0 N-glycosylation protein SLC12 PF03522.15 CDJ40393.1 - 3.4 6.6 14.2 4.4 6.2 14.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Spore_coat_CotO PF14153.6 CDJ40393.1 - 3.7 7.5 22.1 5.4 6.9 22.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Membralin PF09746.9 CDJ40393.1 - 4 6.4 8.2 5.3 6.0 8.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein Peptidase_S64 PF08192.11 CDJ40393.1 - 4.1 5.8 11.0 5 5.5 11.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Band_3_cyto PF07565.13 CDJ40393.1 - 4.5 7.0 13.0 7.1 6.3 13.0 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain VIR_N PF15912.5 CDJ40393.1 - 4.6 6.8 10.2 6.6 6.2 10.2 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF2126 PF09899.9 CDJ40393.1 - 6.2 4.8 10.6 8.3 4.3 10.6 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Sec62 PF03839.16 CDJ40393.1 - 6.5 6.2 10.7 11 5.4 10.7 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 V_ATPase_I PF01496.19 CDJ40393.1 - 7 4.4 15.5 9 4.1 15.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4746 PF15928.5 CDJ40393.1 - 8.2 5.7 11.7 12 5.2 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Otopetrin PF03189.13 CDJ40393.1 - 9 5.0 7.8 11 4.7 7.8 1.2 1 0 0 1 1 1 0 Otopetrin DUF1635 PF07795.11 CDJ40394.1 - 0.1 12.4 8.2 0.12 12.3 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF4554 PF15091.6 CDJ40394.1 - 0.58 9.0 9.1 0.58 9.0 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) TFIIA PF03153.13 CDJ40394.1 - 1.1 9.1 23.0 1.2 9.1 23.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF908 PF06012.12 CDJ40394.1 - 1.1 8.5 8.0 1.3 8.4 8.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) GAGA_bind PF06217.12 CDJ40394.1 - 1.9 8.7 10.2 2.1 8.6 10.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF45 PF01863.17 CDJ40394.1 - 2.5 8.1 9.9 2.8 7.9 9.9 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF966 PF06136.13 CDJ40394.1 - 2.8 7.6 10.7 2.8 7.6 10.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) ALMT PF11744.8 CDJ40394.1 - 3.4 6.4 8.2 3.6 6.3 8.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Suf PF05843.14 CDJ40394.1 - 6.4 6.7 11.8 6.7 6.6 11.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RHH_8 PF17723.1 CDJ40394.1 - 6.4 7.0 8.0 45 4.3 8.0 2.0 1 1 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family DAG_kinase_N PF14513.6 CDJ40394.1 - 7.9 6.7 10.1 10 6.3 10.1 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus OmpH PF03938.14 CDJ40395.1 - 0.29 11.5 6.6 0.4 11.0 6.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ecl1 PF12855.7 CDJ40395.1 - 0.33 12.1 21.3 0.46 11.6 21.3 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Rrn6 PF10214.9 CDJ40395.1 - 1.6 7.1 29.6 1.9 6.9 29.6 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor GREB1 PF15782.5 CDJ40395.1 - 2.4 5.1 15.0 3 4.8 15.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Exonuc_VII_L PF02601.15 CDJ40395.1 - 6.4 6.2 12.0 8.4 5.9 12.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit BAF1_ABF1 PF04684.13 CDJ40398.1 - 1.5 7.8 16.3 1.7 7.6 16.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Menin PF05053.13 CDJ40398.1 - 6.3 5.0 17.7 7.5 4.8 17.7 1.0 1 0 0 1 1 1 0 Menin Spt20 PF12090.8 CDJ40399.1 - 0.93 9.1 16.8 3 7.4 16.8 1.8 1 0 0 1 1 1 0 Spt20 family SARAF PF06682.12 CDJ40400.1 - 2.5 7.6 0.0 2.5 7.6 0.0 4.6 3 2 0 4 4 4 0 SOCE-associated regulatory factor of calcium homoeostasis TTL PF03133.15 CDJ40401.1 - 3e-46 157.9 0.0 3e-46 157.9 0.0 2.1 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 CDJ40401.1 - 1.5e-05 24.4 0.0 0.046 13.0 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 CDJ40401.1 - 6.9e-05 22.2 0.0 6.9e-05 22.2 0.0 4.0 3 1 1 4 4 4 2 YheC/D like ATP-grasp zf-C4H2 PF10146.9 CDJ40401.1 - 0.0016 18.8 3.2 0.0016 18.8 3.2 4.2 4 0 0 4 4 4 2 Zinc finger-containing protein SUIM_assoc PF16619.5 CDJ40401.1 - 0.0051 16.8 4.5 0.0051 16.8 4.5 8.0 7 1 0 7 7 7 3 Unstructured region C-term to UIM in Ataxin3 CMV_1a PF12467.8 CDJ40402.1 - 7.2 6.9 6.8 8.2 6.7 6.8 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Pyr_redox_2 PF07992.14 CDJ40403.1 - 4.9e-42 144.2 0.0 1.7e-41 142.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ40403.1 - 1.1e-10 41.9 0.0 2.3e-07 31.3 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CDJ40403.1 - 0.0088 16.5 0.0 0.21 12.1 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding KCNQ2_u3 PF16642.5 CDJ40403.1 - 0.028 15.4 4.0 0.28 12.2 0.9 2.9 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Pyr_redox_3 PF13738.6 CDJ40403.1 - 0.099 11.9 0.0 6.9 5.8 0.0 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MMS1_N PF10433.9 CDJ40404.1 - 5.1e-122 408.0 0.0 2.4e-121 405.8 0.0 2.1 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CDJ40404.1 - 1.1e-85 287.8 0.0 7.1e-85 285.2 0.0 2.2 2 1 0 2 2 2 1 CPSF A subunit region WD40_like PF17005.5 CDJ40404.1 - 0.19 11.0 0.0 3.8 6.8 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain ANAPC4_WD40 PF12894.7 CDJ40404.1 - 0.21 11.9 0.0 2 8.8 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain UQ_con PF00179.26 CDJ40406.1 - 1.3e-34 118.8 0.0 1.8e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CDJ40406.1 - 0.007 16.2 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 CDJ40406.1 - 0.021 15.1 0.0 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 CDJ40406.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B ACD PF16671.5 CDJ40406.1 - 0.21 9.9 0.7 0.27 9.5 0.7 1.1 1 0 0 1 1 1 0 Actin cross-linking domain DUF3682 PF12446.8 CDJ40407.1 - 0.0028 18.1 4.4 0.0028 18.1 4.4 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF3682) SARAF PF06682.12 CDJ40407.1 - 0.015 15.0 1.9 0.029 14.0 1.9 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis IMUP PF15761.5 CDJ40407.1 - 0.039 14.6 3.2 0.039 14.6 3.2 2.7 3 0 0 3 3 3 0 Immortalisation up-regulated protein Activator_LAG-3 PF11498.8 CDJ40407.1 - 0.86 8.5 25.4 0.36 9.7 7.8 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ40407.1 - 0.89 9.5 21.6 0.2 11.6 8.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1685 PF07939.11 CDJ40407.1 - 0.89 9.3 2.4 1.4 8.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1685) SR-25 PF10500.9 CDJ40407.1 - 2.8 7.5 8.8 0.072 12.7 1.3 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Suf PF05843.14 CDJ40407.1 - 5 7.0 10.5 0.29 11.1 3.8 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PAN_4 PF14295.6 CDJ40411.1 - 3.2e-18 65.4 15.3 6.3e-06 26.0 2.5 4.5 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.26 CDJ40411.1 - 5.8e-12 45.4 16.7 0.00045 20.1 0.9 5.1 5 0 0 5 5 5 4 PAN domain PSI_PsaF PF02507.15 CDJ40412.1 - 0.013 15.4 3.5 0.031 14.1 3.5 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III AAA_23 PF13476.6 CDJ40412.1 - 0.17 12.4 3.4 0.26 11.7 3.4 1.2 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.13 CDJ40412.1 - 0.17 11.8 24.1 0.25 11.3 24.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ40413.1 - 0.016 15.3 3.1 0.016 15.3 3.1 12.9 6 3 3 11 11 11 0 Unstructured region C-term to UIM in Ataxin3 NDUF_B12 PF08122.12 CDJ40413.1 - 0.31 11.1 0.0 0.31 11.1 0.0 3.2 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family TBP PF00352.21 CDJ40414.1 - 6.8e-50 167.0 0.0 8.7e-26 89.7 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CDJ40414.1 - 0.00085 19.4 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Collagen PF01391.18 CDJ40414.1 - 0.0045 16.7 17.2 0.012 15.3 17.2 1.7 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) NapE PF06796.11 CDJ40415.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE DHHC PF01529.20 CDJ40416.1 - 8.8e-26 90.6 9.1 8.8e-26 90.6 9.1 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase EI24 PF07264.11 CDJ40416.1 - 0.29 11.3 12.1 2.6 8.3 12.5 2.0 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) TFIIA PF03153.13 CDJ40416.1 - 0.38 10.7 40.3 0.33 10.9 16.4 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF3481 PF11980.8 CDJ40416.1 - 2 8.1 4.7 6.3 6.6 4.7 1.8 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein Zein PF01559.16 CDJ40417.1 - 0.82 9.2 32.3 1.3 8.6 32.3 1.3 1 0 0 1 1 1 0 Zein seed storage protein PP2C_2 PF13672.6 CDJ40417.1 - 4.6 6.8 16.0 6.3 6.4 16.0 1.4 1 1 0 1 1 1 0 Protein phosphatase 2C PAF PF15715.5 CDJ40418.1 - 0.007 17.0 3.9 0.007 17.0 3.9 4.2 6 0 0 6 6 3 1 PCNA-associated factor histone like domain Nop14 PF04147.12 CDJ40418.1 - 0.74 8.0 24.7 1.2 7.2 24.7 1.2 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpc4 PF05132.14 CDJ40418.1 - 0.99 9.8 9.4 0.6 10.5 6.7 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF913 PF06025.12 CDJ40418.1 - 1.7 7.6 6.9 3.8 6.4 6.9 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Merozoite_SPAM PF07133.11 CDJ40418.1 - 1.7 8.6 31.2 2.7 7.9 31.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) LTV PF04180.14 CDJ40418.1 - 2.2 7.9 18.7 4.1 7.0 18.7 1.4 1 0 0 1 1 1 0 Low temperature viability protein BUD22 PF09073.10 CDJ40418.1 - 2.2 7.5 25.6 7.5 5.8 25.6 1.9 1 0 0 1 1 1 0 BUD22 Asp-B-Hydro_N PF05279.11 CDJ40418.1 - 4.3 7.3 23.3 8.1 6.4 23.3 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PTPRCAP PF15713.5 CDJ40418.1 - 6.2 7.1 33.3 24 5.2 33.3 2.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF2052 PF09747.9 CDJ40418.1 - 9.1 6.4 25.6 5 7.2 22.8 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4746 PF15928.5 CDJ40418.1 - 9.3 5.6 16.9 16 4.8 16.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MMR_HSR1 PF01926.23 CDJ40419.1 - 1.7e-08 34.6 0.0 3.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SR-25 PF10500.9 CDJ40419.1 - 0.0034 17.0 13.8 0.0034 17.0 13.8 7.4 4 3 3 7 7 7 1 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ40419.1 - 0.0076 16.2 14.6 0.0076 16.2 14.6 3.1 2 1 0 2 2 2 1 SPX domain FeoB_N PF02421.18 CDJ40419.1 - 0.043 13.4 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF4667 PF15700.5 CDJ40419.1 - 0.057 13.5 0.1 0.057 13.5 0.1 5.4 4 1 1 5 5 5 0 Domain of unknown function (DUF4667) Presenilin PF01080.17 CDJ40419.1 - 2.3 6.9 25.5 0.34 9.6 2.7 3.0 3 0 0 3 3 3 0 Presenilin Zip PF02535.22 CDJ40419.1 - 6.6 5.8 15.6 0.37 10.0 1.6 2.8 3 0 0 3 3 3 0 ZIP Zinc transporter DUF4148 PF13663.6 CDJ40419.1 - 7.5 6.8 23.6 0.17 12.1 5.7 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DnaJ PF00226.31 CDJ40420.1 - 5.7e-29 100.0 0.9 9.8e-29 99.3 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain COX4 PF02936.14 CDJ40420.1 - 0.027 14.5 0.1 0.043 13.8 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV GW PF13457.6 CDJ40420.1 - 0.63 10.7 2.8 0.73 10.5 0.7 2.0 1 1 1 2 2 2 0 GW (Gly-Tryp) dipeptide domain FA_hydroxylase PF04116.13 CDJ40421.1 - 7e-17 62.0 10.0 7e-17 62.0 10.0 1.7 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.28 CDJ40421.1 - 6.5e-10 39.0 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain OTCace_N PF02729.21 CDJ40422.1 - 5.3e-34 117.4 0.0 5.3e-34 117.4 0.0 3.8 3 0 0 3 3 3 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 CDJ40422.1 - 2.4e-23 82.9 0.9 5e-22 78.7 0.0 3.5 3 1 0 3 3 3 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MORN PF02493.20 CDJ40423.1 - 2.9e-20 70.9 43.0 1.9e-05 24.3 2.7 7.4 7 0 0 7 7 7 5 MORN repeat Pex14_N PF04695.13 CDJ40423.1 - 0.86 10.2 6.7 0.15 12.7 3.3 1.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NEMP PF10225.9 CDJ40424.1 - 0.13 12.0 0.1 0.13 12.0 0.1 3.2 3 1 1 4 4 4 0 NEMP family MMR_HSR1_Xtn PF16897.5 CDJ40425.1 - 3.6e-34 117.0 0.1 5.9e-34 116.3 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CDJ40425.1 - 1.9e-19 69.8 0.0 3.4e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CDJ40425.1 - 6.1e-14 51.8 0.0 1.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CDJ40425.1 - 6.5e-09 35.5 0.0 1.4e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ40425.1 - 4.1e-05 23.7 0.1 0.12 12.4 0.0 2.3 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 CDJ40425.1 - 0.00013 21.9 0.0 0.0011 18.9 0.0 2.3 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 CDJ40425.1 - 0.0009 18.8 0.0 0.072 12.6 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CDJ40425.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 CDJ40425.1 - 0.0068 16.9 0.0 0.018 15.5 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 CDJ40425.1 - 0.0079 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ40425.1 - 0.015 15.7 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 CDJ40425.1 - 0.03 13.3 0.0 0.62 9.0 0.0 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 CDJ40425.1 - 0.046 13.9 0.0 0.15 12.3 0.0 1.9 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 CDJ40425.1 - 0.055 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain RED_N PF07808.13 CDJ40426.1 - 0.028 14.0 0.3 0.033 13.8 0.3 1.0 1 0 0 1 1 1 0 RED-like protein N-terminal region Suf PF05843.14 CDJ40427.1 - 0.046 13.7 10.4 0.06 13.3 10.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ40427.1 - 0.087 12.8 18.9 0.093 12.7 18.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serinc PF03348.15 CDJ40427.1 - 0.13 11.2 0.8 0.14 11.0 0.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Lin-8 PF03353.15 CDJ40427.1 - 0.41 10.2 6.5 0.51 9.9 6.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Med15 PF09606.10 CDJ40427.1 - 0.47 9.1 17.5 0.51 9.0 17.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Sin_N PF04801.13 CDJ40427.1 - 1.2 8.3 11.4 1.3 8.2 11.4 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region S36_mt PF10937.8 CDJ40427.1 - 5.6 8.6 11.2 0.5 12.0 4.7 2.0 2 0 0 2 2 2 0 Ribosomal protein S36, mitochondrial SbcCD_C PF13558.6 CDJ40427.1 - 6 7.2 10.8 2.6 8.4 7.6 2.0 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit TFIIA PF03153.13 CDJ40428.1 - 0.83 9.6 7.1 0.56 10.1 4.9 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Clathrin_lg_ch PF01086.17 CDJ40429.1 - 0.0071 16.4 0.7 0.0071 16.4 0.7 3.3 4 0 0 4 4 4 1 Clathrin light chain ORC_WH_C PF18137.1 CDJ40429.1 - 0.01 15.9 13.2 3.6 7.7 0.2 3.7 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal Tir_receptor_N PF07490.11 CDJ40429.1 - 0.012 15.5 0.2 0.012 15.5 0.2 2.7 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) N-terminus FAM60A PF15396.6 CDJ40429.1 - 0.23 11.5 10.2 0.31 11.0 0.3 3.4 3 0 0 3 3 3 0 Protein Family FAM60A Connexin PF00029.19 CDJ40429.1 - 0.76 9.5 6.2 20 4.8 1.7 3.1 3 0 0 3 3 3 0 Connexin Band_3_cyto PF07565.13 CDJ40429.1 - 1.1 9.0 15.0 0.57 9.9 4.2 3.5 3 0 0 3 3 3 0 Band 3 cytoplasmic domain TPR_2 PF07719.17 CDJ40431.1 - 2.7e-12 45.8 13.7 0.00043 20.2 0.4 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ40431.1 - 1.6e-11 43.5 7.0 0.0072 16.1 1.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ40431.1 - 6.8e-06 25.9 7.7 0.23 11.8 0.2 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ40431.1 - 9.9e-05 22.9 8.4 0.0091 16.6 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ40431.1 - 0.00011 22.7 10.6 0.054 14.3 0.2 4.4 4 1 1 5 5 4 2 Tetratricopeptide repeat MIT PF04212.18 CDJ40431.1 - 0.00095 19.2 0.3 0.00095 19.2 0.3 3.4 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 CDJ40431.1 - 0.0012 18.5 2.5 1.3 8.8 0.1 3.6 3 1 1 4 4 4 2 TPR repeat TPR_12 PF13424.6 CDJ40431.1 - 0.0025 18.1 11.9 7.6 6.9 4.2 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ40431.1 - 0.0027 18.2 3.9 0.52 10.9 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ40431.1 - 0.0028 18.2 10.1 2.1 9.2 0.1 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ40431.1 - 0.0041 17.2 1.1 0.044 13.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2239 PF09998.9 CDJ40431.1 - 0.01 15.6 0.2 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) DUF3808 PF10300.9 CDJ40431.1 - 0.012 14.3 1.6 0.017 13.9 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) EcoR124_C PF12008.8 CDJ40431.1 - 0.038 13.7 0.0 0.08 12.6 0.0 1.6 1 1 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal ANAPC3 PF12895.7 CDJ40431.1 - 0.044 14.0 6.7 1 9.7 1.7 3.1 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 CDJ40431.1 - 0.051 13.7 1.1 0.57 10.3 0.1 2.6 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat REV PF00424.18 CDJ40431.1 - 0.062 13.3 0.2 0.35 10.9 0.1 2.2 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) DUF4407 PF14362.6 CDJ40431.1 - 0.076 12.4 0.7 0.1 11.9 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_10 PF13374.6 CDJ40431.1 - 0.24 11.3 4.1 7 6.7 0.1 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ40431.1 - 0.58 10.7 0.0 0.58 10.7 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat PNMA PF14893.6 CDJ40431.1 - 0.77 9.1 5.3 3 7.2 3.7 2.1 1 1 1 2 2 2 0 PNMA BTAD PF03704.17 CDJ40431.1 - 5.1 7.5 9.9 0.47 10.9 4.8 1.9 2 1 0 2 2 1 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 CDJ40431.1 - 7.5 7.5 10.1 8.7 7.3 0.4 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat RsmJ PF04378.13 CDJ40432.1 - 0.11 11.7 0.3 0.17 11.0 0.3 1.2 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ DUF4698 PF15769.5 CDJ40432.1 - 1.7 7.6 11.0 0.056 12.5 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) TFIIA PF03153.13 CDJ40432.1 - 3.1 7.7 10.9 5.3 6.9 10.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WGG PF10273.9 CDJ40434.1 - 8.3e-23 80.9 0.7 1.5e-22 80.0 0.7 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Tautomerase_2 PF14552.6 CDJ40434.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme PAZ PF02170.22 CDJ40435.1 - 6.3e-10 39.0 0.1 1.9e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 PAZ domain Piwi PF02171.17 CDJ40435.1 - 3e-07 30.0 0.0 1.2e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Piwi domain FhuF PF06276.12 CDJ40435.1 - 0.11 12.9 0.2 0.33 11.4 0.2 1.9 2 0 0 2 2 2 0 Ferric iron reductase FhuF-like transporter Sec7 PF01369.20 CDJ40439.1 - 4.5e-66 222.0 0.0 7e-66 221.4 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CDJ40439.1 - 8.4e-12 45.3 0.0 3.1e-11 43.4 0.0 2.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Pex16 PF08610.10 CDJ40440.1 - 3.5e-27 95.4 0.8 7.4e-27 94.4 0.8 1.4 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF4120 PF13496.6 CDJ40441.1 - 0.063 13.6 0.1 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4120) PARP PF00644.20 CDJ40442.1 - 0.0014 18.3 0.0 0.004 16.8 0.0 1.8 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain MA3 PF02847.17 CDJ40443.1 - 1.7e-28 98.8 1.5 1.5e-09 37.8 0.0 3.2 3 0 0 3 3 3 3 MA3 domain DUF445 PF04286.12 CDJ40443.1 - 0.14 11.9 0.0 0.61 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DUF3357 PF11837.8 CDJ40444.1 - 0.093 13.2 3.1 0.082 13.4 1.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Kelch_4 PF13418.6 CDJ40445.1 - 1.7e-35 120.8 12.1 2.3e-08 33.9 0.0 6.8 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ40445.1 - 3.3e-28 97.2 1.3 4.8e-06 26.4 0.2 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CDJ40445.1 - 1.1e-24 86.1 6.7 7.8e-07 29.2 0.0 7.1 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ40445.1 - 1.2e-24 85.7 1.8 4.1e-07 30.0 0.2 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.15 CDJ40445.1 - 4.8e-17 61.2 12.5 2.9e-05 23.9 0.2 6.5 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 CDJ40445.1 - 1.1e-16 60.1 6.6 4.6e-05 22.9 0.0 5.8 6 0 0 6 6 6 3 Kelch motif DUF4110 PF13422.6 CDJ40445.1 - 2.6e-14 53.1 0.0 2.6e-14 53.1 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Alpha_GJ PF03229.13 CDJ40445.1 - 0.14 12.7 0.3 0.31 11.6 0.3 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J PIEZO PF15917.5 CDJ40445.1 - 1.1 8.7 11.5 0.075 12.5 3.4 2.5 2 0 0 2 2 2 0 Piezo CUE PF02845.16 CDJ40446.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 CUE domain Lipase_3 PF01764.25 CDJ40447.1 - 5.1e-17 62.1 0.0 9.4e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDJ40447.1 - 0.00054 20.6 0.9 0.00054 20.6 0.9 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ40447.1 - 0.00078 18.8 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 CDJ40447.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase RNA_pol_Rpc4 PF05132.14 CDJ40447.1 - 2.8 8.4 7.0 3.4 8.1 0.4 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 Presenilin PF01080.17 CDJ40447.1 - 9.7 4.8 7.3 0.33 9.7 1.5 1.4 2 0 0 2 2 2 0 Presenilin Ribosomal_S3Ae PF01015.18 CDJ40449.1 - 1e-89 299.5 0.1 1.3e-89 299.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 CDJ40449.1 - 0.19 11.3 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Kelch_3 PF13415.6 CDJ40450.1 - 2.8e-17 62.5 2.7 2.7e-07 30.7 0.2 5.3 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ40450.1 - 6.4e-17 61.2 0.6 0.0016 18.4 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 CDJ40450.1 - 1.3e-13 50.7 6.7 2.1e-05 24.4 0.1 5.7 5 0 0 5 5 5 3 Galactose oxidase, central domain HATPase_c_3 PF13589.6 CDJ40450.1 - 1.4e-09 37.9 0.0 2.7e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_1 PF01344.25 CDJ40450.1 - 5.5e-05 22.7 0.2 1.6 8.4 0.0 3.9 4 0 0 4 4 4 2 Kelch motif HATPase_c PF02518.26 CDJ40450.1 - 0.00023 21.6 0.0 0.00045 20.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_6 PF13964.6 CDJ40450.1 - 0.0024 18.1 3.1 0.14 12.5 0.2 4.1 2 2 3 5 5 5 1 Kelch motif PDCD2_C PF04194.13 CDJ40451.1 - 1.9e-34 119.3 0.3 4.7e-33 114.7 0.1 2.2 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain vATP-synt_E PF01991.18 CDJ40452.1 - 2.7e-60 203.2 1.8 3.3e-60 202.9 1.8 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4239 PF14023.6 CDJ40452.1 - 0.031 14.0 5.5 0.093 12.4 5.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Helicase_PWI PF18149.1 CDJ40452.1 - 0.038 14.2 4.5 0.047 13.9 3.0 1.9 2 0 0 2 2 2 0 N-terminal helicase PWI domain IL13 PF03487.13 CDJ40452.1 - 0.082 12.7 1.6 0.11 12.2 0.4 1.8 2 0 0 2 2 2 0 Interleukin-13 CemA PF03040.14 CDJ40452.1 - 0.42 10.5 4.3 0.61 10.0 4.3 1.3 1 0 0 1 1 1 0 CemA family Selenoprotein_S PF06936.11 CDJ40452.1 - 5.5 6.8 6.9 9.1 6.0 6.9 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) TIP120 PF08623.10 CDJ40452.1 - 8.2 6.2 10.6 27 4.5 7.3 2.4 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) CutA1 PF03091.15 CDJ40453.1 - 1.4e-33 114.7 1.3 1.7e-33 114.4 1.3 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein DUF3082 PF11282.8 CDJ40453.1 - 0.071 13.4 1.1 0.086 13.1 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) Ribosomal_S19 PF00203.21 CDJ40454.1 - 3.1e-30 103.9 0.1 4.2e-30 103.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 LRR_4 PF12799.7 CDJ40456.1 - 1.1e-18 67.0 30.4 1.2e-06 28.7 2.6 4.2 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ40456.1 - 7.4e-15 54.5 34.4 4.5e-07 29.5 4.3 3.7 2 1 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 CDJ40456.1 - 4.9e-06 26.2 2.4 0.00067 19.2 0.3 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 CDJ40456.1 - 9.7e-06 25.5 15.5 5 8.1 0.0 6.5 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 CDJ40456.1 - 2.4e-05 24.0 14.9 1.3 9.2 0.1 6.2 6 0 0 6 6 6 2 Leucine Rich repeat DRY_EERY PF09750.9 CDJ40457.1 - 4.3e-09 36.7 0.1 4.3e-09 36.7 0.1 3.4 2 1 0 2 2 2 1 Alternative splicing regulator Surp PF01805.20 CDJ40457.1 - 7.2e-09 35.5 1.6 5.2e-08 32.8 0.1 2.4 2 0 0 2 2 2 1 Surp module SHS2_Rpb7-N PF03876.17 CDJ40458.1 - 3.2e-12 46.6 0.0 5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 polyprenyl_synt PF00348.17 CDJ40459.1 - 5.5e-53 179.6 0.0 5.8e-52 176.3 0.0 2.2 1 1 0 1 1 1 1 Polyprenyl synthetase DUF3780 PF12635.7 CDJ40459.1 - 0.00025 20.9 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3780) adh_short PF00106.25 CDJ40461.1 - 1.7e-26 92.9 0.0 3.8e-21 75.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ40461.1 - 2.2e-17 63.4 0.0 3e-14 53.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ40461.1 - 1.2e-06 28.6 0.0 2.8e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 KR domain B-block_TFIIIC PF04182.12 CDJ40462.1 - 1.3e-06 28.4 0.0 5.6e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 CDJ40462.1 - 0.0017 18.2 1.1 4 7.4 0.0 3.5 3 0 0 3 3 3 2 MarR family HTH_5 PF01022.20 CDJ40462.1 - 0.11 12.4 0.0 0.36 10.7 0.0 2.0 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Dishevelled PF02377.15 CDJ40463.1 - 0.053 14.0 3.5 0.091 13.2 3.5 1.3 1 0 0 1 1 1 0 Dishevelled specific domain Wzy_C PF04932.15 CDJ40465.1 - 0.012 15.3 3.2 0.35 10.5 0.0 3.1 3 0 0 3 3 3 0 O-Antigen ligase DUF4064 PF13273.6 CDJ40465.1 - 0.057 13.7 2.6 8.1 6.8 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) G3P_antiterm PF04309.12 CDJ40465.1 - 0.083 12.3 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator DUF4131 PF13567.6 CDJ40465.1 - 2.3 7.8 21.1 0.16 11.6 3.9 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) HSP70 PF00012.20 CDJ40466.1 - 4e-264 877.4 7.7 4.6e-264 877.2 7.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ40466.1 - 2.4e-15 56.2 1.9 4.2e-13 48.8 0.4 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CDJ40466.1 - 0.00016 22.0 1.4 2.6 8.5 0.0 3.9 3 1 0 3 3 3 2 Cell division protein FtsA DUF5398 PF17376.2 CDJ40466.1 - 0.0038 17.8 0.7 0.0094 16.5 0.7 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5398) FGGY_C PF02782.16 CDJ40466.1 - 0.014 15.1 0.1 0.04 13.6 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain ATP-synt_B PF00430.18 CDJ40466.1 - 1.5 8.9 8.0 3.5 7.7 8.0 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF1090 PF06476.12 CDJ40466.1 - 2 8.6 7.5 4.3 7.5 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Med19 PF10278.9 CDJ40467.1 - 0.025 14.5 15.6 0.042 13.8 15.6 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SRP-alpha_N PF04086.13 CDJ40467.1 - 0.091 12.7 10.9 0.12 12.3 10.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zinc_ribbon_2 PF13240.6 CDJ40467.1 - 0.28 10.9 2.3 0.61 9.9 2.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DTHCT PF08070.11 CDJ40467.1 - 0.68 10.7 33.2 0.46 11.2 30.8 1.8 1 1 1 2 2 2 0 DTHCT (NUC029) region NAM-associated PF14303.6 CDJ40467.1 - 0.85 10.3 15.1 1.4 9.7 15.1 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain FancD2 PF14631.6 CDJ40467.1 - 0.88 6.9 6.6 1.2 6.5 6.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SWIRM-assoc_2 PF16496.5 CDJ40467.1 - 0.96 8.3 13.6 1.2 7.9 13.6 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF4614 PF15391.6 CDJ40467.1 - 1.3 9.0 15.8 2 8.4 15.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Neur_chan_memb PF02932.16 CDJ40467.1 - 1.6 8.8 4.0 2 8.4 4.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIF_alpha PF05793.12 CDJ40467.1 - 1.8 7.1 19.3 2.3 6.7 19.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 CDJ40467.1 - 2.4 6.8 7.5 2.9 6.6 7.5 1.1 1 0 0 1 1 1 0 Presenilin DUF3827 PF12877.7 CDJ40467.1 - 3 6.1 13.0 3.7 5.8 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Apt1 PF10351.9 CDJ40467.1 - 5.5 5.7 14.5 7.1 5.4 14.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4710 PF15828.5 CDJ40467.1 - 5.7 7.1 13.0 9.7 6.4 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) NPR3 PF03666.13 CDJ40467.1 - 6.3 5.5 13.7 8 5.1 13.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nucleo_P87 PF07267.11 CDJ40467.1 - 8.4 5.1 6.4 11 4.7 6.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAM220 PF15487.6 CDJ40467.1 - 9.6 5.7 12.9 12 5.4 12.9 1.1 1 0 0 1 1 1 0 FAM220 family RskA PF10099.9 CDJ40468.1 - 1.4 9.2 0.0 1.4 9.2 0.0 6.5 6 2 0 6 6 6 0 Anti-sigma-K factor rskA PIG-X PF08320.12 CDJ40471.1 - 1.3e-12 48.1 0.2 2.1e-11 44.2 0.2 2.4 1 1 0 1 1 1 1 PIG-X / PBN1 REV PF00424.18 CDJ40472.1 - 0.041 13.9 9.6 0.093 12.8 1.7 3.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) APP_Cu_bd PF12924.7 CDJ40472.1 - 0.056 14.2 0.1 0.25 12.1 0.1 2.2 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD RNase_Zc3h12a PF11977.8 CDJ40473.1 - 1.8e-20 73.3 2.4 2.6e-20 72.8 0.0 2.3 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain N6_N4_Mtase PF01555.18 CDJ40473.1 - 0.0084 15.8 0.1 0.0084 15.8 0.1 2.0 2 0 0 2 2 2 1 DNA methylase DCX PF03607.17 CDJ40474.1 - 4.5e-09 36.3 0.0 1.1e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Doublecortin p25-alpha PF05517.12 CDJ40474.1 - 2.9e-08 34.0 0.0 4.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 p25-alpha CAP_N PF01213.19 CDJ40474.1 - 0.2 11.1 0.3 0.29 10.6 0.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Citrate_synt PF00285.21 CDJ40475.1 - 3.5e-92 309.3 0.3 1.4e-91 307.3 0.0 1.8 2 0 0 2 2 2 1 Citrate synthase, C-terminal domain DUF3883 PF13020.6 CDJ40478.1 - 1.3e-19 70.0 0.1 2.6e-19 69.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) Cupin_8 PF13621.6 CDJ40479.1 - 0.0047 16.7 0.0 0.008 15.9 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain zf-HC2 PF13490.6 CDJ40479.1 - 0.013 15.7 0.2 0.013 15.7 0.2 2.1 3 0 0 3 3 3 0 Putative zinc-finger Cupin_8 PF13621.6 CDJ40480.1 - 6.7e-27 94.8 0.0 2.3e-26 93.1 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CDJ40480.1 - 0.00046 19.7 0.1 0.059 12.8 0.0 2.7 3 0 0 3 3 3 2 Cupin superfamily protein Seryl_tRNA_N PF02403.22 CDJ40480.1 - 0.11 12.7 1.0 0.2 11.9 1.0 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rieske PF00355.26 CDJ40481.1 - 3.9e-11 42.7 0.1 7.3e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 CDJ40481.1 - 0.038 14.5 0.1 0.11 13.0 0.1 1.8 1 1 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region Phe_tRNA-synt_N PF02912.18 CDJ40486.1 - 0.099 12.6 2.6 2.6 8.0 0.0 3.6 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain SET PF00856.28 CDJ40486.1 - 0.13 12.7 0.1 0.91 9.9 0.0 2.5 2 0 0 2 2 2 0 SET domain PyrBI_leader PF08052.11 CDJ40486.1 - 0.13 12.2 0.1 0.39 10.7 0.1 1.7 1 0 0 1 1 1 0 PyrBI operon leader peptide CLZ PF16526.5 CDJ40486.1 - 3.1 8.2 17.1 6.1 7.3 1.7 3.7 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MCC-bdg_PDZ PF10506.9 CDJ40486.1 - 5.1 7.2 10.8 0.8 9.8 3.6 2.9 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF724 PF05266.14 CDJ40486.1 - 5.7 6.7 11.4 2 8.2 4.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) EXS PF03124.14 CDJ40488.1 - 7.8e-67 225.9 10.0 1.1e-66 225.4 10.0 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CDJ40488.1 - 1.2e-17 64.9 12.3 1.4e-16 61.4 12.3 2.3 1 1 0 1 1 1 1 SPX domain DUF3774 PF12609.8 CDJ40488.1 - 2.5 9.2 5.9 0.32 12.0 0.4 2.2 2 1 0 2 2 2 0 Wound-induced protein LIP PF03583.14 CDJ40489.1 - 1.6 8.0 10.2 1.3 8.3 3.3 2.0 2 0 0 2 2 2 0 Secretory lipase YqfQ PF14181.6 CDJ40490.1 - 0.31 11.2 2.3 1.9 8.6 1.2 2.4 2 0 0 2 2 2 0 YqfQ-like protein Fringe PF02434.16 CDJ40491.1 - 1.8e-17 63.6 0.0 5.4e-07 29.3 0.0 3.2 3 0 0 3 3 3 3 Fringe-like DUF4770 PF15994.5 CDJ40492.1 - 0.15 12.3 15.8 0.16 12.2 7.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) SID-1_RNA_chan PF13965.6 CDJ40492.1 - 0.73 8.2 2.0 1.7 7.0 2.0 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CSG2 PF16965.5 CDJ40492.1 - 0.95 8.3 3.8 2.4 7.0 3.8 1.6 1 0 0 1 1 1 0 Ceramide synthase regulator DUF1980 PF09323.10 CDJ40492.1 - 3 7.7 9.7 1 9.2 5.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) PAT1 PF09770.9 CDJ40492.1 - 3 6.0 33.4 0.36 9.0 18.1 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Folate_carrier PF01770.18 CDJ40492.1 - 3.3 6.3 3.9 7.7 5.1 3.9 1.5 1 0 0 1 1 1 0 Reduced folate carrier Med15 PF09606.10 CDJ40492.1 - 7 5.2 54.6 0.065 11.9 20.8 2.8 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal LMF1 PF06762.14 CDJ40493.1 - 6.5e-13 48.6 0.6 2.2e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 Lipase maturation factor TMEM51 PF15345.6 CDJ40493.1 - 0.0092 15.9 2.3 0.0092 15.9 2.3 1.6 2 0 0 2 2 2 1 Transmembrane protein 51 Spt20 PF12090.8 CDJ40493.1 - 0.013 15.2 11.4 0.013 15.2 11.4 2.2 2 0 0 2 2 2 0 Spt20 family SARAF PF06682.12 CDJ40493.1 - 0.03 14.0 1.5 0.04 13.6 1.5 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SUIM_assoc PF16619.5 CDJ40493.1 - 0.036 14.1 0.1 0.036 14.1 0.1 3.1 2 2 0 2 2 1 0 Unstructured region C-term to UIM in Ataxin3 Tau95 PF09734.9 CDJ40493.1 - 0.049 14.4 1.5 0.13 13.1 0.6 1.9 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DNApol_Exo PF18136.1 CDJ40493.1 - 0.11 11.6 0.9 0.17 11.0 0.9 1.3 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain ANAPC_CDC26 PF10471.9 CDJ40493.1 - 0.12 13.3 19.7 0.26 12.1 10.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Presenilin PF01080.17 CDJ40493.1 - 0.12 11.1 0.4 0.16 10.7 0.4 1.3 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 CDJ40493.1 - 0.14 11.0 16.8 0.031 13.2 8.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Ndc1_Nup PF09531.10 CDJ40493.1 - 0.83 8.3 3.5 1 8.0 3.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4834 PF16118.5 CDJ40493.1 - 6.6 7.8 11.3 2.7 9.0 7.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ATP-synt_E PF05680.12 CDJ40493.1 - 7.6 7.0 9.6 14 6.1 4.8 2.2 2 0 0 2 2 2 0 ATP synthase E chain TERB2 PF15101.6 CDJ40493.1 - 7.7 6.5 9.6 8.1 6.4 6.3 2.0 2 0 0 2 2 2 0 Telomere-associated protein TERB2 zf-RanBP PF00641.18 CDJ40494.1 - 1.6e-06 27.3 5.2 1.6e-06 27.3 5.2 2.1 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Coilin_N PF15862.5 CDJ40494.1 - 0.27 11.0 0.0 0.27 11.0 0.0 4.4 4 1 1 5 5 5 0 Coilin N-terminus Dynamin_M PF01031.20 CDJ40495.1 - 1.7e-69 234.2 2.2 4.5e-69 232.8 0.0 2.5 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 CDJ40495.1 - 4.3e-27 95.2 0.1 2e-26 93.1 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 CDJ40495.1 - 1.2e-22 79.8 0.1 4.6e-22 78.0 0.1 2.1 1 0 0 1 1 1 1 Dynamin GTPase effector domain SUIM_assoc PF16619.5 CDJ40495.1 - 1.2e-07 31.7 0.1 0.00086 19.3 0.0 4.3 1 1 1 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 DUF4726 PF15855.5 CDJ40495.1 - 0.027 14.7 1.6 0.027 14.7 1.6 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4726) Glyco_hydro_57 PF03065.15 CDJ40495.1 - 0.045 13.0 0.2 0.098 11.8 0.2 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 SipA PF09052.10 CDJ40495.1 - 0.081 12.5 0.9 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 SipA N-terminal domain LPD22 PF18834.1 CDJ40495.1 - 0.14 12.4 4.1 7.5 6.8 2.5 2.9 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 MPM1 PF17234.2 CDJ40495.1 - 5.9 7.1 7.3 0.63 10.3 0.2 2.3 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Na_H_Exchanger PF00999.21 CDJ40496.1 - 4.9e-45 154.0 38.6 7e-45 153.4 38.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Presenilin PF01080.17 CDJ40496.1 - 0.26 10.0 15.0 0.81 8.4 0.1 2.6 2 0 0 2 2 2 0 Presenilin Apt1 PF10351.9 CDJ40496.1 - 0.27 10.0 14.6 0.021 13.7 3.2 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain Cpn10 PF00166.21 CDJ40497.1 - 1.8e-40 136.9 0.2 4.4e-19 68.3 0.1 2.1 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit Cupin_3 PF05899.12 CDJ40497.1 - 0.048 13.4 0.2 0.64 9.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF861) AMP-binding PF00501.28 CDJ40499.1 - 1.9e-79 267.3 0.0 2.7e-79 266.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DUF2477 PF10631.9 CDJ40499.1 - 0.13 12.9 2.5 0.41 11.3 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) RPN2_C PF18004.1 CDJ40500.1 - 0.014 15.3 2.1 0.014 15.3 2.1 2.6 4 0 0 4 4 4 0 26S proteasome regulatory subunit RPN2 C-terminal domain SLC12 PF03522.15 CDJ40500.1 - 0.13 11.3 6.4 1.4 7.9 5.7 2.1 2 0 0 2 2 2 0 Solute carrier family 12 EPL1 PF10513.9 CDJ40500.1 - 0.16 12.4 4.6 0.1 13.0 1.9 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like PAT1 PF09770.9 CDJ40500.1 - 2.5 6.3 15.9 4.2 5.5 15.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TIMELESS PF04821.14 CDJ40500.1 - 8.1 5.6 12.7 0.19 11.0 6.0 1.7 2 0 0 2 2 2 0 Timeless protein TERB2 PF15101.6 CDJ40500.1 - 9.7 6.2 15.1 29 4.6 15.1 1.8 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RAP1 PF07218.11 CDJ40501.1 - 8.9 4.4 12.7 14 3.8 12.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF202 PF02656.15 CDJ40504.1 - 1.3e-13 51.1 6.3 1.3e-13 51.1 6.3 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF202) VTC PF09359.10 CDJ40504.1 - 3e-13 49.8 0.0 6.4e-08 32.3 0.0 2.4 2 0 0 2 2 2 2 VTC domain SPX PF03105.19 CDJ40504.1 - 1.5e-05 25.2 1.0 1.5e-05 25.2 1.0 5.9 4 1 2 6 6 6 4 SPX domain DUF21 PF01595.20 CDJ40505.1 - 4.6e-27 94.9 5.0 4.6e-27 94.9 5.0 3.2 3 1 0 3 3 3 1 Cyclin M transmembrane N-terminal domain SPX PF03105.19 CDJ40505.1 - 0.0015 18.5 0.4 0.0015 18.5 0.4 2.9 2 1 1 3 3 3 1 SPX domain TFIIA PF03153.13 CDJ40505.1 - 0.14 12.1 47.2 0.43 10.5 8.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 CDJ40505.1 - 0.19 10.5 18.5 0.14 11.0 5.9 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF572 PF04502.13 CDJ40505.1 - 0.49 10.0 17.7 0.47 10.0 2.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF2052 PF09747.9 CDJ40505.1 - 2.3 8.3 19.9 1.6 8.8 4.4 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Lin-8 PF03353.15 CDJ40505.1 - 8.3 5.9 26.5 2.6 7.5 9.7 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SNF PF00209.18 CDJ40506.1 - 5.6e-53 180.4 11.2 1e-51 176.3 11.2 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family zf-met PF12874.7 CDJ40508.1 - 8.6e-06 26.0 0.4 8.6e-06 26.0 0.4 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ40508.1 - 0.0046 17.2 2.8 0.0046 17.2 2.8 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.12 CDJ40508.1 - 0.049 13.9 2.1 0.095 12.9 2.1 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Dehydrin PF00257.19 CDJ40508.1 - 0.063 13.8 1.0 0.063 13.8 1.0 4.0 3 2 0 3 3 3 0 Dehydrin Metallophos PF00149.28 CDJ40509.1 - 4.3e-15 56.8 0.2 7e-14 52.8 0.4 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Phage_Gp23 PF10669.9 CDJ40509.1 - 0.016 15.5 1.6 0.033 14.5 1.6 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) FlaC_arch PF05377.11 CDJ40510.1 - 0.29 11.6 7.0 2.6 8.5 0.4 4.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Draxin PF15550.6 CDJ40511.1 - 0.5 10.2 11.0 0.55 10.0 11.0 1.0 1 0 0 1 1 1 0 Draxin SRP-alpha_N PF04086.13 CDJ40511.1 - 1.7 8.5 17.8 2 8.3 17.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RIFIN PF02009.16 CDJ40511.1 - 2.6 7.8 14.9 3.5 7.4 14.9 1.1 1 0 0 1 1 1 0 Rifin Neur_chan_memb PF02932.16 CDJ40511.1 - 2.7 8.0 11.9 3 7.8 11.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ40511.1 - 8.5 6.2 28.7 10 6.0 28.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPR_2 PF13041.6 CDJ40512.1 - 7.2e-50 167.0 0.0 2.5e-09 37.2 0.0 9.0 5 4 5 10 10 10 7 PPR repeat family PPR_1 PF12854.7 CDJ40512.1 - 2.6e-30 103.8 2.1 0.00099 18.8 0.0 9.8 10 1 0 10 10 10 7 PPR repeat PPR PF01535.20 CDJ40512.1 - 7.7e-29 97.9 9.9 0.00013 21.9 0.0 11.7 13 0 0 13 13 13 5 PPR repeat PPR_3 PF13812.6 CDJ40512.1 - 1.1e-25 89.5 0.0 2.4e-06 27.5 0.0 7.6 5 2 3 8 8 8 6 Pentatricopeptide repeat domain PPR_long PF17177.4 CDJ40512.1 - 1.5e-09 37.5 30.5 0.0001 21.8 0.1 6.2 2 2 2 5 5 5 3 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 CDJ40512.1 - 5.8e-06 26.1 0.0 0.5 10.2 0.0 5.2 5 1 2 7 7 7 2 Mitochondrial ATPase expression SDH_alpha PF03313.15 CDJ40512.1 - 0.00025 20.8 20.8 0.00025 20.8 20.8 3.0 2 1 0 2 2 2 1 Serine dehydratase alpha chain JHD PF17811.1 CDJ40512.1 - 2 9.0 0.0 2 9.0 0.0 4.1 5 0 0 5 5 5 0 Jumonji helical domain HCNGP PF07818.13 CDJ40513.1 - 1.7e-11 44.6 0.0 3e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein K_channel_TID PF07941.11 CDJ40513.1 - 0.0041 17.5 6.1 0.0074 16.7 6.1 1.4 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain RskA PF10099.9 CDJ40513.1 - 0.022 15.0 3.1 0.035 14.4 3.1 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Rrn6 PF10214.9 CDJ40513.1 - 0.25 9.8 10.6 0.3 9.5 10.6 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peptidase_C1 PF00112.23 CDJ40514.1 - 2.7e-30 106.1 9.5 5.5e-15 56.0 0.4 3.4 2 1 0 2 2 2 2 Papain family cysteine protease CathepsinC_exc PF08773.11 CDJ40514.1 - 1.5e-09 38.2 6.0 2e-09 37.7 0.3 3.5 2 1 0 2 2 2 1 Cathepsin C exclusion domain Propeptide_C1 PF08127.13 CDJ40514.1 - 0.0013 18.6 1.3 0.0027 17.5 1.3 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide TFIIA PF03153.13 CDJ40514.1 - 0.033 14.2 14.3 0.048 13.7 14.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ40514.1 - 0.039 14.2 17.6 0.32 11.3 6.7 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA GREB1 PF15782.5 CDJ40514.1 - 0.052 10.7 4.3 0.067 10.3 4.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 CDJ40514.1 - 3.1 6.5 4.8 4.2 6.0 4.8 1.2 1 0 0 1 1 1 0 Presenilin TSP_1 PF00090.19 CDJ40516.1 - 0.0043 17.2 33.5 0.033 14.4 0.3 4.5 3 1 0 3 3 3 2 Thrombospondin type 1 domain Adeno_terminal PF02459.15 CDJ40516.1 - 0.028 12.8 0.7 0.039 12.4 0.7 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DcpS_C PF11969.8 CDJ40517.1 - 1.1e-05 25.8 0.1 0.0077 16.7 0.0 2.9 3 0 0 3 3 3 2 Scavenger mRNA decapping enzyme C-term binding Macoilin PF09726.9 CDJ40518.1 - 0.37 9.3 13.6 0.48 8.9 13.6 1.2 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 CDJ40518.1 - 2.8 5.6 11.8 4 5.1 11.8 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ThiJ_like PF17124.5 CDJ40520.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 ThiJ/PfpI family-like Nuc_sug_transp PF04142.15 CDJ40521.1 - 3.4e-105 351.7 10.1 4.2e-105 351.4 10.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 CDJ40521.1 - 5.6e-07 29.1 9.0 1e-05 24.9 9.0 2.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 CDJ40521.1 - 1.1e-06 28.9 28.9 6.3e-05 23.2 4.5 2.8 3 0 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 CDJ40521.1 - 4e-06 26.0 1.8 4e-06 26.0 1.8 1.6 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EmrE PF13536.6 CDJ40521.1 - 1.1e-05 25.2 8.3 0.00017 21.3 8.3 2.2 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter PUNUT PF16913.5 CDJ40521.1 - 5.5e-05 22.5 2.2 5.5e-05 22.5 2.2 1.6 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 CDJ40521.1 - 0.074 12.4 10.9 0.036 13.4 1.8 2.7 2 1 0 2 2 2 0 Triose-phosphate Transporter family Mon1 PF03164.14 CDJ40521.1 - 0.18 10.8 0.2 0.27 10.2 0.2 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 ENOD93 PF03386.14 CDJ40521.1 - 0.48 10.3 5.1 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 Early nodulin 93 ENOD93 protein LCCL PF03815.19 CDJ40523.1 - 1.1e-30 105.5 0.2 3.4e-16 59.1 0.0 2.2 1 1 1 2 2 2 2 LCCL domain SRCR PF00530.18 CDJ40525.1 - 0.0001 22.7 1.1 0.04 14.4 0.1 2.3 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain LCCL PF03815.19 CDJ40526.1 - 1.5e-18 66.7 0.0 2.3e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 LCCL domain PLAT PF01477.23 CDJ40526.1 - 1.9e-07 31.6 0.0 3.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 PLAT/LH2 domain Ribosomal_L32e PF01655.18 CDJ40527.1 - 1e-44 151.3 0.3 1.3e-44 151.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 pPIWI_RE_X PF13111.6 CDJ40527.1 - 0.061 12.5 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 pPIWI_RE module N-terminal domain CDP-OH_P_transf PF01066.21 CDJ40528.1 - 2.4e-14 53.8 0.1 2.4e-14 53.8 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PNP_UDP_1 PF01048.20 CDJ40529.1 - 6.4e-31 107.4 0.0 1.1e-30 106.7 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily DUF3357 PF11837.8 CDJ40531.1 - 9.1e-06 26.1 5.4 2.9 8.4 0.0 4.3 4 0 0 4 4 4 3 Domain of unknown function (DUF3357) EphA2_TM PF14575.6 CDJ40531.1 - 0.0011 19.8 2.5 5.8 7.9 0.0 4.2 4 0 0 4 4 4 1 Ephrin type-A receptor 2 transmembrane domain DUF2298 PF10060.9 CDJ40531.1 - 0.0013 17.6 0.2 0.0018 17.1 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) DUF3180 PF11377.8 CDJ40531.1 - 1 9.5 28.7 6.3 6.9 1.9 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3180) DUF3704 PF12488.8 CDJ40531.1 - 2 8.1 11.3 23 4.8 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3704) DUF3382 PF11862.8 CDJ40531.1 - 3.8 7.8 13.4 0.18 12.1 1.8 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) DUF3357 PF11837.8 CDJ40532.1 - 6.5e-06 26.6 10.0 3.9 8.0 0.0 5.2 5 0 0 5 5 5 3 Domain of unknown function (DUF3357) DUF2298 PF10060.9 CDJ40532.1 - 0.0012 17.7 0.7 0.0043 15.8 0.2 1.9 1 1 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) DUF2079 PF09852.9 CDJ40532.1 - 0.13 11.1 2.5 3.5 6.4 0.0 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2079) CopD PF05425.13 CDJ40532.1 - 0.38 11.2 27.2 1.1 9.7 4.7 3.6 1 1 3 4 4 4 0 Copper resistance protein D DUF2162 PF09930.9 CDJ40532.1 - 0.82 9.0 9.2 2 7.8 0.6 3.9 5 0 0 5 5 5 0 Predicted transporter (DUF2162) DUF3180 PF11377.8 CDJ40532.1 - 3 8.0 33.9 8.5 6.5 1.9 4.3 2 1 1 4 4 4 0 Protein of unknown function (DUF3180) DUF3382 PF11862.8 CDJ40532.1 - 3.4 8.0 18.3 0.077 13.3 2.3 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF3382) DUF3752 PF12572.8 CDJ40533.1 - 9.1 6.8 34.2 0.038 14.5 15.4 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF3752) Actin PF00022.19 CDJ40534.1 - 9e-77 258.4 0.0 4.2e-76 256.2 0.0 1.8 1 1 0 1 1 1 1 Actin FtsA PF14450.6 CDJ40534.1 - 0.035 14.5 0.0 5.9 7.4 0.0 3.1 3 0 0 3 3 3 0 Cell division protein FtsA MreB_Mbl PF06723.13 CDJ40534.1 - 0.13 11.0 0.7 9.3 5.0 0.0 3.0 3 0 0 3 3 3 0 MreB/Mbl protein Dynamitin PF04912.14 CDJ40535.1 - 8.7e-37 127.4 12.1 2.2e-33 116.1 10.1 2.3 2 1 0 2 2 2 2 Dynamitin DUF4995 PF16386.5 CDJ40535.1 - 0.014 15.3 2.5 5 7.2 0.3 3.7 3 1 0 3 3 3 0 Domain of unknown function Baculo_PEP_C PF04513.12 CDJ40535.1 - 0.29 11.2 8.8 0.92 9.5 0.2 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 CDJ40535.1 - 0.38 11.2 3.2 7.8 7.0 0.0 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Troponin PF00992.20 CDJ40535.1 - 0.91 9.8 7.7 4.7 7.5 1.2 2.9 3 0 0 3 3 3 0 Troponin FlaC_arch PF05377.11 CDJ40535.1 - 2.1 8.8 5.0 14 6.2 0.2 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4094 PF13334.6 CDJ40535.1 - 3.8 8.0 6.4 6.5 7.2 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) CLZ PF16526.5 CDJ40535.1 - 7.2 7.0 15.8 8.2 6.9 2.5 3.7 4 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Muted PF14942.6 CDJ40535.1 - 9.1 6.6 8.5 4.2 7.7 0.5 3.1 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein zf-C3HC4 PF00097.25 CDJ40536.1 - 7.7e-07 28.9 7.0 1.6e-06 27.9 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ40536.1 - 1.4e-05 24.8 7.5 4.4e-05 23.2 7.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CDJ40536.1 - 8.9e-05 22.3 4.7 0.00018 21.3 4.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 CDJ40536.1 - 0.00021 21.1 6.5 0.00039 20.2 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ40536.1 - 0.00025 20.9 8.3 0.00055 19.8 8.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDJ40536.1 - 0.00042 20.4 10.6 0.00088 19.4 10.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CDJ40536.1 - 0.00065 19.7 5.7 0.0016 18.4 5.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDJ40536.1 - 0.0023 18.2 8.7 0.005 17.2 8.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.8 CDJ40536.1 - 0.051 13.4 2.1 0.12 12.2 2.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PagP PF07017.11 CDJ40536.1 - 0.16 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP Prok-RING_4 PF14447.6 CDJ40536.1 - 0.17 11.7 6.3 0.33 10.8 6.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FAST_2 PF08368.12 CDJ40536.1 - 0.57 11.0 2.2 5.6 7.8 2.0 2.5 1 1 0 1 1 1 0 FAST kinase-like protein, subdomain 2 zf-RING_4 PF14570.6 CDJ40536.1 - 1.4 8.8 9.7 2.6 7.9 9.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.6 CDJ40536.1 - 7.1 7.2 7.0 15 6.2 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_4 PF14570.6 CDJ40542.1 - 1e-19 70.1 10.6 2e-19 69.1 10.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CDJ40542.1 - 7.3e-07 29.0 7.9 1.4e-06 28.0 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CDJ40542.1 - 2.9e-06 27.0 0.0 5.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 CDJ40542.1 - 0.0041 17.8 0.1 0.0041 17.8 0.1 2.5 2 0 0 2 2 2 1 Torus domain zf-RING_2 PF13639.6 CDJ40542.1 - 0.01 16.2 11.4 0.01 16.2 11.4 1.9 2 0 0 2 2 2 0 Ring finger domain Baculo_IE-1 PF05290.11 CDJ40542.1 - 0.18 11.8 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Rsc14 PF08586.10 CDJ40542.1 - 0.22 12.4 5.0 4.2 8.2 2.7 2.9 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Prok-RING_4 PF14447.6 CDJ40542.1 - 0.35 10.8 9.5 12 5.8 9.7 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 CDJ40542.1 - 0.5 10.5 2.8 1.3 9.2 2.8 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 CDJ40542.1 - 7.3 6.8 9.5 24 5.2 9.5 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING TFIIA PF03153.13 CDJ40544.1 - 0.2 11.6 20.8 0.26 11.2 20.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NAP PF00956.18 CDJ40544.1 - 0.64 9.1 11.0 0.96 8.6 11.0 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) GRIM-19 PF06212.12 CDJ40544.1 - 1.2 9.0 6.7 0.78 9.7 4.3 2.0 1 1 1 2 2 2 0 GRIM-19 protein RskA PF10099.9 CDJ40545.1 - 0.64 10.3 12.9 0.3 11.4 1.3 3.2 3 0 0 3 3 3 0 Anti-sigma-K factor rskA V-SNARE_C PF12352.8 CDJ40546.1 - 0.0029 17.8 0.4 0.0029 17.8 0.4 3.3 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus DUF3433 PF11915.8 CDJ40546.1 - 0.16 12.4 0.3 0.35 11.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) Pkinase PF00069.25 CDJ40547.1 - 1e-16 61.1 0.0 3.6e-15 56.0 0.0 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ40547.1 - 9e-10 38.3 0.0 8.7e-09 35.0 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase ALMT PF11744.8 CDJ40547.1 - 2.1 7.1 22.0 0.049 12.5 12.7 2.8 3 0 0 3 3 3 0 Aluminium activated malate transporter SPC12 PF06645.13 CDJ40549.1 - 1.4e-19 69.9 0.8 1.7e-19 69.6 0.8 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Sec62 PF03839.16 CDJ40549.1 - 0.098 12.2 0.2 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Big_5 PF13205.6 CDJ40550.1 - 1.5e-11 44.9 0.0 0.0011 19.7 0.0 4.7 3 1 0 3 3 3 3 Bacterial Ig-like domain Notch PF00066.17 CDJ40550.1 - 1.2e-05 25.7 7.4 1.2e-05 25.7 7.4 3.8 2 0 0 2 2 2 1 LNR domain DUF4381 PF14316.6 CDJ40550.1 - 0.016 15.5 0.2 0.016 15.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) CopC PF04234.12 CDJ40550.1 - 0.03 15.4 0.1 4.2 8.5 0.0 3.9 4 1 0 4 4 4 0 CopC domain SIT PF15330.6 CDJ40550.1 - 0.034 14.6 0.0 0.034 14.6 0.0 2.8 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT CcmD PF04995.14 CDJ40550.1 - 0.44 10.7 10.6 6 7.0 10.6 3.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SHR3_chaperone PF08229.11 CDJ40550.1 - 5.4 5.9 7.3 3.5 6.6 4.4 1.9 2 0 0 2 2 2 0 ER membrane protein SH3 Mut7-C PF01927.16 CDJ40551.1 - 0.11 12.5 0.2 0.16 12.0 0.2 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain ATG_C PF09333.11 CDJ40552.1 - 0.14 12.5 1.2 3.2 8.2 0.1 2.6 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain DSPc PF00782.20 CDJ40554.1 - 1.2e-11 44.6 0.0 2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CBM_20 PF00686.19 CDJ40554.1 - 0.00082 19.2 0.0 0.029 14.3 0.0 2.5 2 0 0 2 2 2 1 Starch binding domain DUF442 PF04273.13 CDJ40554.1 - 0.042 13.9 0.1 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Putative phosphatase (DUF442) DivIVA PF05103.13 CDJ40554.1 - 0.053 13.6 0.0 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 DivIVA protein Y_phosphatase PF00102.27 CDJ40554.1 - 0.059 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_L22e PF01776.17 CDJ40556.1 - 2.6e-44 150.0 3.1 3.2e-44 149.8 3.1 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family AMPK1_CBM PF16561.5 CDJ40556.1 - 0.019 15.2 0.0 0.062 13.5 0.0 1.8 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase pP_pnuc_1 PF18165.1 CDJ40556.1 - 0.027 14.3 0.8 2.9 7.8 0.0 2.1 1 1 1 2 2 2 0 Predicted pPIWI-associating nuclease DUF3228 PF11539.8 CDJ40557.1 - 2.3e-80 268.7 0.0 2.7e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) bPH_4 PF06713.11 CDJ40557.1 - 0.046 13.8 0.1 14 5.8 0.0 2.6 2 1 0 2 2 2 0 Bacterial PH domain eIF3_p135 PF12807.7 CDJ40558.1 - 3.3e-08 33.8 0.0 1.5e-07 31.6 0.0 2.1 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 CDJ40558.1 - 0.081 13.2 3.6 1.4 9.3 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PWI PF01480.17 CDJ40559.1 - 1.9e-28 98.6 0.0 3.1e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 PWI domain PYC_OADA PF02436.18 CDJ40559.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Conserved carboxylase domain CALM_bind PF16025.5 CDJ40559.1 - 0.056 13.9 0.7 0.1 13.1 0.7 1.3 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding DIRP PF06584.13 CDJ40559.1 - 0.057 13.6 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 DIRP PhoD PF09423.10 CDJ40562.1 - 1.3e-13 50.8 1.6 2.7e-12 46.4 1.6 2.2 1 1 0 1 1 1 1 PhoD-like phosphatase DUF4757 PF15949.5 CDJ40562.1 - 0.023 15.2 2.8 0.029 14.8 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4757) TerD PF02342.18 CDJ40563.1 - 3.2e-05 23.5 0.0 0.00023 20.7 0.0 2.2 2 0 0 2 2 2 1 TerD domain Spc7 PF08317.11 CDJ40563.1 - 0.0068 15.3 0.5 0.011 14.6 0.5 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 CDJ40563.1 - 0.046 13.8 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AIP3 PF03915.13 CDJ40563.1 - 0.059 12.5 0.1 0.083 12.0 0.1 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 NPV_P10 PF05531.12 CDJ40563.1 - 0.071 13.6 0.9 2.5 8.6 0.9 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein BCAS2 PF05700.11 CDJ40563.1 - 0.074 12.7 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Dynamitin PF04912.14 CDJ40563.1 - 0.21 10.9 3.0 0.25 10.6 1.8 1.7 1 1 1 2 2 2 0 Dynamitin ABC_tran_CTD PF16326.5 CDJ40563.1 - 0.25 11.6 4.9 1 9.7 1.9 3.1 1 1 2 3 3 3 0 ABC transporter C-terminal domain Apt1 PF10351.9 CDJ40563.1 - 0.45 9.3 2.2 0.82 8.5 2.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain LPP PF04728.13 CDJ40563.1 - 0.5 10.8 2.4 6 7.3 0.6 2.9 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DSS1_SEM1 PF05160.13 CDJ40564.1 - 0.014 15.5 22.5 0.54 10.4 22.5 2.3 1 1 0 1 1 1 0 DSS1/SEM1 family FAM193_C PF15914.5 CDJ40564.1 - 5.6 6.8 5.9 3.1 7.6 0.1 2.2 2 0 0 2 2 2 0 FAM193 family C-terminal DEAD PF00270.29 CDJ40565.1 - 2.4e-38 131.7 0.0 5.2e-38 130.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ40565.1 - 4.5e-18 65.6 0.0 1.2e-16 61.1 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Rhomboid PF01694.22 CDJ40567.1 - 1.5e-28 99.6 13.2 1.5e-28 99.6 13.2 1.6 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 CDJ40567.1 - 0.076 13.6 0.0 0.076 13.6 0.0 2.2 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) YbjQ_1 PF01906.17 CDJ40568.1 - 5e-19 68.9 0.4 7.9e-19 68.2 0.4 1.3 1 0 0 1 1 1 1 Putative heavy-metal-binding Pkinase PF00069.25 CDJ40569.1 - 4.8e-39 134.3 0.0 1.2e-36 126.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ40569.1 - 2.7e-23 82.6 0.0 3.8e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ40569.1 - 5.3e-08 32.5 0.0 1e-07 31.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CDJ40569.1 - 7e-06 25.1 0.0 8.6e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ40569.1 - 6.8e-05 22.9 0.7 0.00017 21.6 0.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family MMR_HSR1 PF01926.23 CDJ40571.1 - 4.3e-14 52.6 0.0 8.3e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ40571.1 - 1.5e-06 28.2 0.0 0.049 13.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CDJ40571.1 - 5.1e-05 22.9 0.0 7.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ40571.1 - 0.014 15.5 0.0 0.28 11.2 0.1 2.9 3 0 0 3 3 3 0 Dynamin family GTP_EFTU PF00009.27 CDJ40571.1 - 0.015 14.9 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CDJ40571.1 - 0.11 12.3 0.0 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation YL1 PF05764.13 CDJ40571.1 - 1.3 9.1 15.4 0.12 12.4 2.9 2.5 2 0 0 2 2 2 0 YL1 nuclear protein Radical_SAM PF04055.21 CDJ40572.1 - 4.7e-17 62.9 0.0 3.9e-16 59.9 0.0 2.3 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 CDJ40572.1 - 1.2e-15 57.4 0.5 1.4e-14 53.9 0.5 2.7 1 1 0 1 1 1 1 Uncharacterized protein family UPF0004 TEA PF01285.18 CDJ40572.1 - 0.02 15.0 0.5 5.5 7.1 0.0 2.7 2 0 0 2 2 2 0 TEA/ATTS domain DUF1450 PF07293.11 CDJ40572.1 - 0.035 13.9 0.1 8.6 6.3 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) Phg_2220_C PF09524.10 CDJ40572.1 - 0.19 11.8 0.0 0.68 10.0 0.0 1.9 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) VPS13_C PF16909.5 CDJ40573.1 - 1.7e-24 86.5 0.4 2.7e-20 72.9 0.0 2.7 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CDJ40573.1 - 8.9e-06 25.7 0.0 0.00032 20.6 0.0 2.9 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal ATG_C PF09333.11 CDJ40573.1 - 4.7e-05 23.7 0.0 0.00018 21.8 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain AAA_2 PF07724.14 CDJ40576.1 - 2.6e-52 177.4 0.0 4.7e-48 163.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CDJ40576.1 - 2e-31 108.0 0.6 2e-31 108.0 0.6 3.1 1 1 2 3 3 3 1 AAA lid domain AAA PF00004.29 CDJ40576.1 - 6.2e-26 91.4 0.0 4.7e-14 52.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CDJ40576.1 - 2.8e-24 85.0 2.1 2.8e-24 85.0 2.1 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 CDJ40576.1 - 2.8e-20 72.2 3.7 4.2e-11 42.8 0.1 2.9 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 CDJ40576.1 - 3e-19 69.4 0.0 1.3e-13 51.2 0.0 3.7 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ40576.1 - 1.3e-12 48.5 3.1 1.5e-05 25.4 0.0 5.2 3 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 CDJ40576.1 - 9e-09 35.7 1.0 0.00069 19.9 0.0 4.7 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 CDJ40576.1 - 7.3e-08 32.3 0.0 1.4e-05 24.9 0.0 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CDJ40576.1 - 1.7e-07 31.3 0.0 0.01 15.8 0.0 3.3 3 1 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 CDJ40576.1 - 3.9e-07 30.0 0.1 0.13 11.9 0.0 4.0 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.6 CDJ40576.1 - 7.6e-07 29.7 0.2 0.01 16.4 0.0 3.4 3 1 0 3 3 2 2 AAA domain TniB PF05621.11 CDJ40576.1 - 1e-06 28.3 0.0 0.0077 15.7 0.0 3.8 2 1 0 2 2 2 1 Bacterial TniB protein ATPase_2 PF01637.18 CDJ40576.1 - 3.2e-05 24.0 1.5 2 8.3 0.0 4.5 4 1 1 5 5 4 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 CDJ40576.1 - 4.5e-05 23.4 0.3 2.5 8.0 0.0 3.5 3 0 0 3 3 3 1 RsgA GTPase AAA_7 PF12775.7 CDJ40576.1 - 4.8e-05 23.0 0.0 0.036 13.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region RuvB_N PF05496.12 CDJ40576.1 - 0.00011 22.0 0.1 5.4 6.7 0.0 4.3 3 1 1 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CDJ40576.1 - 0.00013 22.0 0.0 0.36 10.8 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CDJ40576.1 - 0.00018 21.5 0.0 0.14 12.1 0.0 3.2 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 CDJ40576.1 - 0.00051 20.4 0.0 0.42 11.0 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Roc PF08477.13 CDJ40576.1 - 0.00052 20.2 0.0 1.9 8.8 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 CDJ40576.1 - 0.0015 18.7 1.0 0.84 9.8 0.0 4.1 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 CDJ40576.1 - 0.0018 17.7 0.1 5.9 6.2 0.0 3.5 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CDJ40576.1 - 0.0024 17.2 1.7 0.2 10.9 0.0 3.5 4 0 0 4 4 4 1 Zeta toxin AAA_19 PF13245.6 CDJ40576.1 - 0.0059 16.9 0.2 0.34 11.2 0.0 3.4 4 0 0 4 4 2 1 AAA domain ABC_tran_CTD PF16326.5 CDJ40576.1 - 0.0074 16.5 4.8 0.0074 16.5 4.8 2.9 1 1 1 2 2 2 1 ABC transporter C-terminal domain NTPase_1 PF03266.15 CDJ40576.1 - 0.0099 15.8 1.2 10 6.0 0.0 3.8 4 0 0 4 4 3 0 NTPase AAA_25 PF13481.6 CDJ40576.1 - 0.012 15.3 0.1 0.47 10.0 0.1 3.1 2 1 1 3 3 3 0 AAA domain ResIII PF04851.15 CDJ40576.1 - 0.013 15.5 0.0 0.79 9.7 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit MutS_III PF05192.18 CDJ40576.1 - 0.015 15.5 0.1 0.015 15.5 0.1 2.6 2 2 0 2 2 2 0 MutS domain III ABC_tran PF00005.27 CDJ40576.1 - 0.017 15.7 0.0 0.78 10.3 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_3 PF07726.11 CDJ40576.1 - 0.021 14.7 0.0 9.1 6.2 0.0 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 CDJ40576.1 - 0.032 13.2 0.1 0.33 9.9 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region ATP_bind_1 PF03029.17 CDJ40576.1 - 0.036 13.9 0.1 0.97 9.2 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Bac_DnaA PF00308.18 CDJ40576.1 - 0.037 13.8 0.0 1.5 8.6 0.0 2.8 3 0 0 3 3 2 0 Bacterial dnaA protein AAA_24 PF13479.6 CDJ40576.1 - 0.047 13.4 0.0 12 5.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 CDJ40576.1 - 0.072 12.7 0.0 10 5.7 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 CDJ40576.1 - 0.11 12.2 0.0 23 4.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.6 CDJ40576.1 - 0.17 12.3 1.9 5 7.6 0.0 3.7 3 1 0 3 3 2 0 AAA domain AAA_28 PF13521.6 CDJ40576.1 - 0.17 12.1 6.8 3.5 7.8 0.0 3.6 4 1 0 4 4 2 0 AAA domain SPACA9 PF15120.6 CDJ40576.1 - 0.18 11.6 1.5 0.47 10.2 1.5 1.7 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 AAA_23 PF13476.6 CDJ40576.1 - 0.19 12.2 13.9 5.6 7.4 0.0 4.1 2 2 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDJ40576.1 - 0.61 9.8 5.5 16 5.1 0.0 4.0 3 1 0 3 3 2 0 AAA domain LUC7 PF03194.15 CDJ40576.1 - 1.1 8.8 4.7 2.3 7.8 4.7 1.5 1 0 0 1 1 1 0 LUC7 N_terminus zf-C2H2_11 PF16622.5 CDJ40577.1 - 0.021 14.6 1.4 0.037 13.8 1.4 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type Lactamase_B_2 PF12706.7 CDJ40578.1 - 8.1e-14 51.6 0.1 3.8e-09 36.4 0.1 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ40578.1 - 6.4e-05 23.0 0.0 0.0033 17.5 0.0 2.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 CDJ40578.1 - 0.23 10.9 0.0 0.4 10.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Spt20 PF12090.8 CDJ40578.1 - 1.3 8.6 5.0 1.9 8.0 5.0 1.2 1 0 0 1 1 1 0 Spt20 family Pro-rich PF15240.6 CDJ40579.1 - 4.1e-05 23.9 11.6 4.1e-05 23.9 11.6 1.9 2 0 0 2 2 2 1 Proline-rich SWI-SNF_Ssr4 PF08549.10 CDJ40580.1 - 0.31 9.7 14.3 0.36 9.4 14.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PAT1 PF09770.9 CDJ40580.1 - 1.8 6.7 24.5 2.1 6.5 24.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AUX_IAA PF02309.16 CDJ40580.1 - 4.5 7.1 10.2 6 6.7 10.2 1.2 1 0 0 1 1 1 0 AUX/IAA family Presenilin PF01080.17 CDJ40580.1 - 5 5.8 10.9 6 5.5 10.9 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ40580.1 - 9 4.8 20.9 11 4.6 20.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 CDJ40581.1 - 4.5e-23 81.1 0.8 0.0034 18.2 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ40581.1 - 8.5e-07 29.2 0.1 0.15 12.4 0.0 3.6 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ40581.1 - 0.0086 15.1 0.1 5.8 5.8 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Spt20 PF12090.8 CDJ40581.1 - 0.13 11.9 11.9 0.81 9.3 3.8 2.0 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 CDJ40581.1 - 0.59 10.2 24.6 0.28 11.3 7.6 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2076 PF09849.9 CDJ40581.1 - 0.9 9.5 18.9 5.9 6.9 12.6 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) AAA PF00004.29 CDJ40582.1 - 3.4e-42 144.0 0.0 3.4e-42 144.0 0.0 2.3 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ40582.1 - 2.3e-13 49.7 0.2 5.7e-13 48.4 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ40582.1 - 8.5e-06 25.8 0.2 4.4e-05 23.5 0.0 2.4 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDJ40582.1 - 2.1e-05 24.7 2.5 3.2e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 CDJ40582.1 - 6.9e-05 22.7 0.8 0.00016 21.5 0.8 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 CDJ40582.1 - 0.00015 21.5 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ40582.1 - 0.00016 22.1 0.1 0.00016 22.1 0.1 6.0 6 1 1 7 7 6 1 AAA ATPase domain DUF2072 PF09845.9 CDJ40582.1 - 0.00076 19.7 0.8 0.00076 19.7 0.8 2.7 2 0 0 2 2 2 1 Zn-ribbon containing protein AAA_18 PF13238.6 CDJ40582.1 - 0.0048 17.4 0.0 0.035 14.6 0.0 2.6 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 CDJ40582.1 - 0.013 15.2 1.5 0.021 14.6 0.0 2.1 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 CDJ40582.1 - 0.021 15.0 0.0 0.021 15.0 0.0 3.3 4 0 0 4 4 2 0 AAA domain AAA_22 PF13401.6 CDJ40582.1 - 0.027 14.7 0.5 0.027 14.7 0.5 4.3 4 1 0 4 4 3 0 AAA domain AAA_3 PF07726.11 CDJ40582.1 - 0.03 14.2 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CDJ40582.1 - 0.031 13.7 0.1 0.085 12.2 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CDJ40582.1 - 0.031 13.6 0.1 0.23 10.8 0.0 2.3 2 0 0 2 2 2 0 KaiC TIP49 PF06068.13 CDJ40582.1 - 0.033 13.4 2.1 0.043 13.0 0.0 2.0 2 0 0 2 2 2 0 TIP49 P-loop domain TsaE PF02367.17 CDJ40582.1 - 0.073 13.1 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CDJ40582.1 - 0.081 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CDJ40582.1 - 0.085 12.6 0.0 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CDJ40582.1 - 0.1 12.9 0.0 0.1 12.9 0.0 4.2 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.22 CDJ40582.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 CDJ40582.1 - 0.16 11.0 1.1 0.25 10.4 0.0 1.8 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 CDJ40582.1 - 0.44 11.0 0.0 0.44 11.0 0.0 2.8 3 0 0 3 3 1 0 AAA domain AAA_11 PF13086.6 CDJ40582.1 - 1.1 9.0 0.0 1.1 9.0 0.0 4.1 4 0 0 4 4 4 0 AAA domain DUF1018 PF06252.12 CDJ40584.1 - 0.48 11.4 9.5 0.039 14.9 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) K-box PF01486.17 CDJ40584.1 - 0.7 10.1 11.9 0.66 10.2 9.0 2.3 2 1 0 2 2 2 0 K-box region DOR PF14839.6 CDJ40584.1 - 0.75 9.7 8.8 0.76 9.7 8.2 1.4 1 1 0 1 1 1 0 DOR family FlgN PF05130.12 CDJ40584.1 - 1.4 9.4 17.3 0.66 10.5 14.2 2.1 1 1 1 2 2 2 0 FlgN protein N2227 PF07942.12 CDJ40585.1 - 2.3e-75 253.3 0.0 3.2e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 CDJ40585.1 - 0.035 14.7 0.0 0.2 12.3 0.0 2.2 1 1 0 2 2 2 0 Methyltransferase domain DUF4551 PF15087.6 CDJ40585.1 - 0.38 9.5 9.0 0.53 9.1 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TFIIA PF03153.13 CDJ40585.1 - 0.58 10.1 24.4 0.87 9.5 24.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ40585.1 - 1.9 8.0 13.8 2.7 7.4 13.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cwf_Cwc_15 PF04889.12 CDJ40585.1 - 2.2 7.9 16.5 3.2 7.4 16.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BORG_CEP PF14957.6 CDJ40585.1 - 9.8 7.4 7.8 22 6.2 7.8 1.6 1 0 0 1 1 1 0 Cdc42 effector FKBP_N PF01346.18 CDJ40586.1 - 0.00052 20.9 6.3 0.053 14.5 6.3 2.5 1 1 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase ATPase-cat_bd PF12156.8 CDJ40586.1 - 0.14 12.9 1.1 31 5.4 0.1 2.6 2 1 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase RskA PF10099.9 CDJ40586.1 - 1.2 9.4 29.5 1.3 9.3 1.6 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Thioredoxin_4 PF13462.6 CDJ40586.1 - 3.8 7.7 8.4 9.6 6.3 7.7 1.9 2 0 0 2 2 2 0 Thioredoxin WD40 PF00400.32 CDJ40587.1 - 6e-17 61.7 5.2 0.016 16.0 0.0 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ40587.1 - 2e-07 31.2 0.0 0.47 10.8 0.0 4.3 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 CDJ40587.1 - 1e-05 25.7 0.3 2.4e-05 24.6 0.3 1.6 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain RskA PF10099.9 CDJ40587.1 - 0.00063 20.1 4.2 0.00063 20.1 4.2 6.5 4 3 1 5 5 5 1 Anti-sigma-K factor rskA RAB3GAP2_N PF14655.6 CDJ40587.1 - 0.046 13.0 0.0 0.046 13.0 0.0 5.2 7 0 0 7 7 7 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FAM176 PF14851.6 CDJ40587.1 - 0.18 11.5 0.2 0.51 10.0 0.2 1.8 1 0 0 1 1 1 0 FAM176 family Kinesin PF00225.23 CDJ40588.1 - 3.5e-77 259.6 0.0 3.5e-77 259.6 0.0 5.9 6 2 0 7 7 7 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ40588.1 - 1.6e-14 54.1 0.0 6.5e-14 52.1 0.0 5.1 6 1 1 7 7 7 2 Microtubule binding RskA PF10099.9 CDJ40589.1 - 0.032 14.5 0.0 0.032 14.5 0.0 7.3 3 2 2 5 5 5 0 Anti-sigma-K factor rskA Surface_antigen PF11054.8 CDJ40590.1 - 6.7e-62 209.3 0.2 9e-62 208.9 0.2 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen TC1 PF15063.6 CDJ40590.1 - 0.11 12.4 0.0 0.65 9.9 0.0 2.2 2 1 0 2 2 2 0 Thyroid cancer protein 1 Surface_antigen PF11054.8 CDJ40591.1 - 1e-74 251.3 0.0 1.2e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40592.1 - 3.6e-81 272.4 3.9 4.4e-81 272.1 3.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen GCD14 PF08704.10 CDJ40593.1 - 1.3e-63 214.9 0.0 2.9e-39 135.2 0.0 2.1 1 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CDJ40593.1 - 0.0001 22.1 0.0 0.00072 19.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CDJ40593.1 - 0.0026 17.6 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6_Mtase PF02384.16 CDJ40593.1 - 0.07 12.4 0.0 2.8 7.1 0.0 2.1 2 0 0 2 2 2 0 N-6 DNA Methylase RrnaAD PF00398.20 CDJ40593.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Surface_antigen PF11054.8 CDJ40594.1 - 8.1e-76 254.9 0.3 9.5e-76 254.7 0.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40595.1 - 2.5e-76 256.5 5.2 3.1e-76 256.3 5.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40596.1 - 3.6e-61 206.9 2.6 8.8e-61 205.7 2.6 1.5 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40597.1 - 4.7e-63 213.1 7.3 5.6e-63 212.9 7.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF4047 PF13256.6 CDJ40597.1 - 0.041 14.1 0.1 0.081 13.1 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) ADAM_CR_2 PF17771.1 CDJ40597.1 - 0.23 12.0 2.4 8.7 6.9 0.1 2.7 2 1 1 3 3 3 0 ADAM cysteine-rich domain Chromo PF00385.24 CDJ40598.1 - 2.4e-07 30.5 0.1 8.4e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Surface_antigen PF11054.8 CDJ40599.1 - 1.2e-72 244.5 7.3 1.6e-72 244.2 7.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Mitofilin PF09731.9 CDJ40599.1 - 0.061 12.2 0.1 0.074 11.9 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Surface_antigen PF11054.8 CDJ40600.1 - 3.1e-69 233.4 6.8 3.6e-69 233.1 6.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen ATF7IP_BD PF16788.5 CDJ40600.1 - 0.1 12.7 1.2 0.16 12.1 1.2 1.4 1 0 0 1 1 1 0 ATF-interacting protein binding domain Surface_antigen PF11054.8 CDJ40601.1 - 9.2e-66 222.0 0.9 1.1e-65 221.7 0.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40602.1 - 1e-74 251.3 4.2 1.3e-74 251.0 4.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40603.1 - 1.4e-72 244.3 3.4 1.7e-72 244.1 3.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40604.1 - 8.2e-74 248.3 7.6 9.8e-74 248.1 7.6 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40605.1 - 6.7e-76 255.2 2.5 8.5e-76 254.8 2.5 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40606.1 - 1.3e-71 241.1 0.3 1.5e-71 240.9 0.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40607.1 - 2.1e-70 237.1 0.9 2.5e-70 236.9 0.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40608.1 - 1.6e-75 253.9 7.4 1.9e-75 253.7 7.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40609.1 - 4.2e-75 252.6 2.8 5.8e-75 252.1 2.8 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40610.1 - 3.4e-73 246.3 5.5 4.1e-73 246.0 5.5 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40611.1 - 3.7e-61 206.9 5.1 4.8e-61 206.5 5.1 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40612.1 - 5.9e-73 245.5 2.3 8.1e-73 245.1 2.3 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40613.1 - 9.4e-58 195.7 4.3 6.1e-54 183.3 2.2 2.0 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen zinc_ribbon_10 PF10058.9 CDJ40613.1 - 0.026 14.2 0.0 1.8 8.4 0.0 2.7 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Surface_antigen PF11054.8 CDJ40614.1 - 4.9e-61 206.5 12.4 1.6e-56 191.7 8.8 2.1 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40615.1 - 2.4e-74 250.1 5.8 4.2e-74 249.3 5.8 1.3 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen zinc_ribbon_10 PF10058.9 CDJ40615.1 - 0.094 12.5 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Transglut_C PF00927.22 CDJ40615.1 - 0.19 11.9 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain Surface_antigen PF11054.8 CDJ40616.1 - 2e-76 256.9 5.3 2.5e-76 256.6 5.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40617.1 - 1.9e-74 250.4 6.2 2.3e-74 250.1 6.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40618.1 - 3e-72 243.2 3.2 3.8e-72 242.9 3.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40619.1 - 1.7e-76 257.1 5.0 2.1e-76 256.8 5.0 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ40620.1 - 2e-75 253.6 8.5 4.5e-75 252.5 8.5 1.5 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen ABC_tran PF00005.27 CDJ40621.1 - 2.1e-32 112.5 0.0 3.8e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CDJ40621.1 - 2.8e-22 79.7 9.8 6e-22 78.6 9.8 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CDJ40621.1 - 9.7e-05 21.9 0.0 0.0042 16.5 0.0 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ40621.1 - 0.0004 20.8 0.3 0.0017 18.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 CDJ40621.1 - 0.00073 19.4 0.0 0.0064 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 CDJ40621.1 - 0.0033 16.6 0.0 0.0062 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CDJ40621.1 - 0.0066 16.7 0.0 0.036 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CDJ40621.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 CDJ40621.1 - 0.02 14.6 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CDJ40621.1 - 0.044 13.5 0.0 0.083 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CDJ40621.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ABC_membrane_2 PF06472.15 CDJ40621.1 - 0.056 12.8 1.8 0.095 12.1 1.8 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 DEAD PF00270.29 CDJ40621.1 - 0.092 12.5 0.1 1.1 9.0 0.1 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 CDJ40621.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DLIC PF05783.11 CDJ40621.1 - 0.24 10.2 0.0 0.24 10.2 0.0 1.7 2 0 0 2 2 1 0 Dynein light intermediate chain (DLIC) AAA_15 PF13175.6 CDJ40621.1 - 0.24 11.1 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Apt1 PF10351.9 CDJ40621.1 - 1.2 7.9 3.9 1.8 7.3 3.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain ATP-synt_S1 PF05827.12 CDJ40622.1 - 0.013 15.3 1.3 0.014 15.2 0.6 1.3 1 1 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) TMEM52 PF14979.6 CDJ40622.1 - 0.03 14.3 0.2 0.034 14.1 0.2 1.2 1 0 0 1 1 1 0 Transmembrane 52 L51_S25_CI-B8 PF05047.16 CDJ40623.1 - 0.00035 20.4 0.0 0.00066 19.5 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF547 PF04784.14 CDJ40623.1 - 0.092 12.8 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF547 DAGAT PF03982.13 CDJ40624.1 - 1.6e-29 102.8 0.0 2.6e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Pkinase PF00069.25 CDJ40625.1 - 1.8e-66 224.2 0.0 2.6e-66 223.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ40625.1 - 1.8e-32 112.6 0.0 2.9e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ40625.1 - 7.2e-05 22.2 0.1 7.2e-05 22.2 0.1 2.2 2 1 1 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 CDJ40625.1 - 9.1e-05 21.6 0.3 9.1e-05 21.6 0.3 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CDJ40625.1 - 0.0032 16.9 0.6 0.0066 15.8 0.6 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5320 PF17253.2 CDJ40625.1 - 0.058 14.5 0.9 0.14 13.2 0.9 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Activator_LAG-3 PF11498.8 CDJ40625.1 - 0.2 10.6 31.8 0.34 9.8 29.4 2.3 3 0 0 3 3 3 0 Transcriptional activator LAG-3 APH PF01636.23 CDJ40625.1 - 0.23 11.3 5.0 2.2 8.2 0.0 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family PI3K_1B_p101 PF10486.9 CDJ40625.1 - 0.5 8.1 7.0 0.7 7.6 7.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SOBP PF15279.6 CDJ40625.1 - 5.6 7.5 21.4 8.9 6.8 21.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein ANAPC4_WD40 PF12894.7 CDJ40627.1 - 8.6e-05 22.8 0.0 0.023 15.0 0.0 3.5 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ40627.1 - 0.082 13.8 1.1 86 4.3 0.1 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat PUF PF00806.19 CDJ40628.1 - 9.2e-42 138.4 5.6 4.6e-06 26.0 0.0 8.7 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat TBPIP PF07106.13 CDJ40628.1 - 0.059 13.3 1.5 3.5 7.6 0.0 3.7 5 0 0 5 5 5 0 TBPIP/Hop2 winged helix domain Pkinase PF00069.25 CDJ40629.1 - 8e-36 123.8 0.0 9.5e-24 84.2 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ40629.1 - 4.1e-17 62.3 0.0 7.8e-11 41.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ40629.1 - 1.2e-05 24.8 0.0 0.0023 17.3 0.1 2.8 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 CDJ40629.1 - 4.5e-05 23.5 5.3 0.00022 21.2 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ40629.1 - 0.093 12.1 4.7 0.22 10.8 0.1 2.9 1 1 2 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ40629.1 - 0.47 9.2 4.4 0.43 9.3 0.7 2.1 1 1 1 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 CDJ40630.1 - 7.9e-32 110.7 0.2 1e-17 64.4 0.0 3.8 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ40630.1 - 8e-06 25.3 12.4 0.0043 16.4 0.0 4.1 5 0 0 5 5 5 2 Protein tyrosine kinase Exonuc_VII_L PF02601.15 CDJ40630.1 - 0.057 13.0 19.9 0.7 9.4 2.2 3.4 3 0 0 3 3 3 0 Exonuclease VII, large subunit DUF5094 PF17015.5 CDJ40630.1 - 1.6 8.8 10.1 0.36 10.9 0.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5094) FancD2 PF14631.6 CDJ40630.1 - 2.4 5.4 6.2 19 2.4 7.6 1.7 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease DUF4179 PF13786.6 CDJ40630.1 - 9.7 6.7 7.8 5.8 7.5 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Macoilin PF09726.9 CDJ40631.1 - 0.0015 17.2 14.7 0.0023 16.6 14.7 1.3 1 0 0 1 1 1 1 Macoilin family Ras PF00071.22 CDJ40634.1 - 2.9e-15 56.2 0.0 7.2e-15 54.9 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CDJ40634.1 - 3.4e-08 33.7 0.0 1.1e-07 32.0 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CDJ40634.1 - 0.018 15.1 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 CDJ40634.1 - 0.08 13.1 1.2 0.17 12.1 0.0 2.1 3 0 0 3 3 3 0 AAA domain PX PF00787.24 CDJ40635.1 - 9.5e-15 54.6 0.0 2.3e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 PX domain SUIM_assoc PF16619.5 CDJ40635.1 - 0.085 12.9 0.0 0.085 12.9 0.0 11.5 9 4 0 9 9 9 0 Unstructured region C-term to UIM in Ataxin3 Syja_N PF02383.18 CDJ40636.1 - 9e-43 146.8 0.4 7.4e-41 140.5 0.0 3.1 3 0 0 3 3 3 1 SacI homology domain Bcl-2 PF00452.19 CDJ40636.1 - 2.8 8.7 6.3 26 5.6 1.8 3.5 2 1 1 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family Jak1_Phl PF17887.1 CDJ40636.1 - 7.2 6.6 11.2 0.24 11.4 3.8 2.2 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain DUF4366 PF14283.6 CDJ40637.1 - 0.077 13.0 1.3 1.7 8.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Prok-RING_1 PF14446.6 CDJ40638.1 - 0.00023 21.0 0.5 0.00023 21.0 0.5 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD PF00628.29 CDJ40638.1 - 0.01 15.7 1.7 0.01 15.7 1.7 3.6 3 0 0 3 3 3 0 PHD-finger Aminotran_5 PF00266.19 CDJ40639.1 - 4e-27 95.1 0.0 1.5e-26 93.3 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V HHH_6 PF14579.6 CDJ40639.1 - 0.0025 18.0 0.1 2.5 8.4 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif LRR_10 PF18805.1 CDJ40641.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat AAA_2 PF07724.14 CDJ40642.1 - 5e-39 134.1 0.0 1.4e-38 132.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CDJ40642.1 - 5e-23 81.0 2.6 1.1e-22 79.9 2.6 1.5 1 0 0 1 1 1 1 AAA lid domain ClpB_D2-small PF10431.9 CDJ40642.1 - 3.2e-13 49.5 0.4 1.1e-12 47.8 0.0 2.2 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CDJ40642.1 - 1.2e-08 35.0 0.2 9.1e-08 32.2 0.0 2.6 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ40642.1 - 9e-08 32.6 0.0 2.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ40642.1 - 9e-07 28.7 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 CDJ40642.1 - 0.00043 19.6 0.0 0.00091 18.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 CDJ40642.1 - 0.00071 20.0 0.5 0.006 17.0 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain DUF3384 PF11864.8 CDJ40642.1 - 0.001 18.1 0.2 0.0015 17.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Seryl_tRNA_N PF02403.22 CDJ40642.1 - 0.0035 17.6 2.1 0.011 16.0 2.1 1.8 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Bac_DnaA PF00308.18 CDJ40642.1 - 0.004 17.0 0.1 0.53 10.1 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein RuvB_N PF05496.12 CDJ40642.1 - 0.0074 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CDJ40642.1 - 0.012 16.2 0.1 0.082 13.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDJ40642.1 - 0.014 15.6 1.0 2 8.7 0.1 3.4 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 CDJ40642.1 - 0.042 14.1 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CDJ40642.1 - 0.06 13.9 0.2 0.37 11.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 CDJ40642.1 - 0.065 13.3 0.0 0.24 11.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ40642.1 - 0.079 12.9 0.1 0.43 10.5 0.0 2.2 3 0 0 3 3 3 0 RsgA GTPase TMPIT PF07851.13 CDJ40642.1 - 0.19 11.0 0.6 0.28 10.4 0.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Folliculin PF11704.8 CDJ40643.1 - 0.07 13.0 0.1 0.074 12.9 0.1 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Spt20 PF12090.8 CDJ40643.1 - 0.19 11.3 12.6 0.2 11.2 12.6 1.1 1 0 0 1 1 1 0 Spt20 family Fer4_13 PF13370.6 CDJ40643.1 - 1.4 9.6 4.7 2.6 8.7 4.7 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I DUF4554 PF15091.6 CDJ40644.1 - 4.6 6.0 10.3 7 5.4 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) MeMO_Hyd_G PF02964.16 CDJ40645.1 - 0.087 12.8 0.5 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Methane monooxygenase, hydrolase gamma chain YajC PF02699.15 CDJ40646.1 - 0.94 9.4 3.7 1.5 8.8 3.7 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit ATP_bind_3 PF01171.20 CDJ40647.1 - 1.7e-13 50.8 5.4 1.2e-05 25.2 3.4 3.5 2 1 1 3 3 3 3 PP-loop family SpoIIIAH PF12685.7 CDJ40647.1 - 0.013 15.4 10.0 0.022 14.6 7.8 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein SPX PF03105.19 CDJ40647.1 - 9.5 6.0 15.1 16 5.3 15.1 1.5 1 1 0 1 1 1 0 SPX domain SAND PF01342.21 CDJ40648.1 - 0.0036 17.0 5.0 0.016 14.9 1.0 2.4 2 1 0 2 2 2 2 SAND domain Gemini_coat PF00844.18 CDJ40648.1 - 0.018 14.5 1.2 0.019 14.4 1.2 1.1 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family DUF2767 PF10965.8 CDJ40650.1 - 8.3 6.5 6.8 0.69 9.9 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2767) DUF4667 PF15700.5 CDJ40651.1 - 0.27 11.3 33.5 0.079 13.0 15.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) Lin-8 PF03353.15 CDJ40651.1 - 0.41 10.2 22.9 1.6 8.3 4.0 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CCDC24 PF15669.5 CDJ40651.1 - 1 9.2 24.5 1.9 8.3 11.2 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 24 family Apt1 PF10351.9 CDJ40651.1 - 2.3 7.0 19.6 0.7 8.7 9.8 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain GREB1 PF15782.5 CDJ40651.1 - 3.4 4.6 23.7 0.78 6.8 13.2 2.1 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 CDJ40651.1 - 5.8 6.2 10.7 0.19 11.1 2.6 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF572 PF04502.13 CDJ40651.1 - 8.4 5.9 11.5 1.1 8.8 2.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) Ribosomal_S2 PF00318.20 CDJ40652.1 - 0.065 12.4 0.2 0.082 12.1 0.2 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 RskA PF10099.9 CDJ40652.1 - 0.25 11.6 27.0 0.43 10.9 27.0 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Coilin_N PF15862.5 CDJ40652.1 - 0.51 10.1 6.6 0.64 9.8 6.6 1.1 1 0 0 1 1 1 0 Coilin N-terminus Spt20 PF12090.8 CDJ40652.1 - 0.58 9.7 13.4 0.55 9.8 13.4 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ40652.1 - 1.9 8.4 21.8 2 8.3 21.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ40652.1 - 5.1 7.0 9.7 5.4 6.9 9.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ40652.1 - 6.8 5.3 7.5 6.6 5.4 7.5 1.0 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ40652.1 - 8.4 7.4 6.4 10 7.1 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3325 PF11804.8 CDJ40654.1 - 0.069 13.3 7.2 0.088 13.0 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) RskA PF10099.9 CDJ40654.1 - 1.8 8.8 14.6 2.1 8.6 14.6 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Macoilin PF09726.9 CDJ40655.1 - 0.0028 16.3 14.2 0.0059 15.2 14.2 1.5 1 0 0 1 1 1 1 Macoilin family Tmp39 PF10271.9 CDJ40655.1 - 0.026 13.6 0.3 0.026 13.6 0.3 2.1 2 1 0 2 2 2 0 Putative transmembrane protein DUF3853 PF12964.7 CDJ40655.1 - 0.04 14.1 0.1 0.04 14.1 0.1 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF3853) TFIIA PF03153.13 CDJ40655.1 - 0.78 9.7 69.8 0.04 13.9 44.2 3.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 CDJ40655.1 - 6.4 5.1 7.3 22 3.3 7.4 1.9 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Cytochrom_B_N_2 PF13631.6 CDJ40657.1 - 0.016 15.2 0.2 0.02 14.9 0.2 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB SARAF PF06682.12 CDJ40657.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Ribosomal_L1 PF00687.21 CDJ40658.1 - 1.2e-41 142.7 4.0 1.5e-41 142.4 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_S24e PF01282.19 CDJ40659.1 - 3.4e-23 81.4 0.0 6.6e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e P120R PF08062.11 CDJ40659.1 - 0.87 10.0 11.9 1.8 9.0 0.4 2.8 2 0 0 2 2 2 0 P120R (NUC006) repeat TetR_C_11 PF16859.5 CDJ40662.1 - 0.0007 19.9 3.9 0.26 11.6 0.1 2.9 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain Trypan_PARP PF05887.11 CDJ40662.1 - 1.2 9.1 5.9 0.39 10.7 1.8 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SPX PF03105.19 CDJ40663.1 - 0.35 10.7 15.9 0.36 10.7 15.9 1.1 1 0 0 1 1 1 0 SPX domain Importin_rep_4 PF18808.1 CDJ40664.1 - 1.7e-08 34.6 0.0 5.8e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Importin repeat HEAT PF02985.22 CDJ40664.1 - 1.3e-06 28.1 13.8 2.7e-05 24.0 0.0 7.6 8 0 0 8 8 8 1 HEAT repeat Vac14_Fab1_bd PF12755.7 CDJ40664.1 - 6.7e-06 26.6 0.1 0.00028 21.4 0.0 3.2 2 1 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 CDJ40664.1 - 7.1e-06 26.3 34.2 0.0005 20.4 0.1 6.1 3 2 1 4 4 3 3 HEAT repeats HEAT_EZ PF13513.6 CDJ40664.1 - 8.2e-05 23.0 1.6 0.0096 16.4 0.2 8.7 6 4 4 10 10 9 2 HEAT-like repeat Trp_DMAT PF11991.8 CDJ40664.1 - 0.046 13.1 0.5 0.17 11.3 0.1 2.0 2 0 0 2 2 2 0 Tryptophan dimethylallyltransferase RTP1_C1 PF10363.9 CDJ40664.1 - 0.075 13.2 0.4 2.2 8.5 0.0 3.1 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Ecm29 PF13001.7 CDJ40664.1 - 0.082 11.6 0.0 0.21 10.2 0.0 1.6 1 0 0 1 1 1 0 Proteasome stabiliser Adaptin_N PF01602.20 CDJ40664.1 - 0.1 11.2 0.0 2.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region DUF4259 PF14078.6 CDJ40664.1 - 0.13 13.0 3.5 0.21 12.3 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) Cnd1 PF12717.7 CDJ40664.1 - 0.14 12.2 0.5 2.2 8.3 0.0 2.9 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 AAA PF00004.29 CDJ40665.1 - 1.7e-11 44.7 0.0 2.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ40665.1 - 4.8e-06 26.3 0.3 8.5e-06 25.5 0.3 1.4 1 0 0 1 1 1 1 AAA+ lid domain ketoacyl-synt PF00109.26 CDJ40666.1 - 2.1e-06 27.5 0.4 2.1e-06 27.5 0.4 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thi4 PF01946.17 CDJ40666.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.0 1 0 0 1 1 1 0 Thi4 family HTH_51 PF18558.1 CDJ40666.1 - 0.06 13.2 1.4 0.065 13.1 1.4 1.0 1 0 0 1 1 1 0 Helix-turn-helix domain Androgen_recep PF02166.16 CDJ40666.1 - 0.44 9.3 8.0 0.47 9.3 8.0 1.0 1 0 0 1 1 1 0 Androgen receptor EphA2_TM PF14575.6 CDJ40667.1 - 1.4 9.9 5.3 3.4 8.6 5.3 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain zf-UBP PF02148.19 CDJ40667.1 - 4 7.9 15.8 1.5 9.2 13.3 1.7 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein DUF4778 PF16008.5 CDJ40669.1 - 0.63 10.1 8.8 0.047 13.7 3.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4778) SpoIIIAH PF12685.7 CDJ40669.1 - 2.6 7.8 6.4 4.8 6.9 6.4 1.5 1 1 0 1 1 1 0 SpoIIIAH-like protein Herpes_DNAp_acc PF04929.12 CDJ40669.1 - 9.8 5.0 6.3 16 4.4 6.3 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor AAA_23 PF13476.6 CDJ40670.1 - 1.9 9.0 5.6 3.4 8.1 1.2 2.4 2 0 0 2 2 2 0 AAA domain SKA1 PF07160.12 CDJ40671.1 - 0.28 11.0 6.7 0.12 12.2 4.6 1.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 TFIIA PF03153.13 CDJ40672.1 - 0.61 10.0 21.4 0.87 9.5 21.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4718 PF15842.5 CDJ40673.1 - 1.8e-05 24.6 1.5 2.6e-05 24.1 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4718) DUF1645 PF07816.11 CDJ40673.1 - 0.097 13.2 7.7 0.16 12.5 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Miga PF10265.9 CDJ40673.1 - 0.1 11.6 5.3 0.13 11.3 5.3 1.1 1 0 0 1 1 1 0 Mitoguardin RAP1 PF07218.11 CDJ40673.1 - 6.9 4.8 5.4 7.8 4.6 5.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4692 PF15763.5 CDJ40673.1 - 7.6 7.0 9.6 12 6.3 9.6 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) EIF4E-T PF10477.9 CDJ40674.1 - 0.091 11.6 5.2 0.18 10.6 5.2 1.4 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E CDT1_C PF16679.5 CDJ40675.1 - 0.011 16.1 0.4 0.056 13.9 0.2 2.3 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain MFS_1 PF07690.16 CDJ40676.1 - 0.00064 18.7 3.4 0.00082 18.4 3.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CagY_M PF07337.11 CDJ40676.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 DC-EC Repeat DUF3510 PF12022.8 CDJ40677.1 - 0.05 14.0 0.5 0.068 13.5 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) XLF PF09302.11 CDJ40677.1 - 0.075 13.2 1.6 0.11 12.7 1.6 1.1 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component TFIIA PF03153.13 CDJ40677.1 - 5.4 6.9 10.5 6.9 6.5 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ40678.1 - 0.014 14.2 11.9 0.015 14.1 11.9 1.1 1 0 0 1 1 1 0 Presenilin Velvet PF11754.8 CDJ40678.1 - 0.029 14.3 5.1 0.029 14.3 5.1 1.1 1 0 0 1 1 1 0 Velvet factor CbtA PF09490.10 CDJ40678.1 - 0.044 13.5 0.3 0.058 13.2 0.3 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) FHIPEP PF00771.20 CDJ40678.1 - 0.35 9.3 3.2 0.36 9.2 3.2 1.2 1 0 0 1 1 1 0 FHIPEP family RR_TM4-6 PF06459.12 CDJ40678.1 - 0.94 9.2 18.7 1.5 8.5 18.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 CDJ40678.1 - 2.3 6.0 15.7 2.6 5.9 15.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLAIN PF15301.6 CDJ40678.1 - 2.6 7.2 16.8 3.3 6.8 16.8 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family Ndc1_Nup PF09531.10 CDJ40678.1 - 4.4 5.9 8.3 4.4 5.9 8.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 CDJ40678.1 - 4.6 6.3 11.0 7.2 5.7 11.0 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.15 CDJ40678.1 - 5.8 5.7 9.8 7.4 5.4 9.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF913 PF06025.12 CDJ40678.1 - 9.8 5.0 9.8 13 4.6 9.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MCU PF04678.13 CDJ40678.1 - 9.9 6.2 8.9 14 5.7 8.9 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Ribosomal_L22 PF00237.19 CDJ40679.1 - 1.1e-31 109.1 0.2 1.5e-31 108.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Holin_BhlA PF10960.8 CDJ40679.1 - 0.18 11.8 0.1 0.31 11.0 0.1 1.6 1 1 0 1 1 1 0 BhlA holin family Chorion_2 PF03964.15 CDJ40682.1 - 0.0034 18.2 2.7 0.01 16.6 0.6 2.1 2 0 0 2 2 2 1 Chorion family 2 IMUP PF15761.5 CDJ40682.1 - 0.062 14.0 0.9 0.062 14.0 0.9 2.5 2 1 0 2 2 2 0 Immortalisation up-regulated protein OMPdecase PF00215.24 CDJ40683.1 - 5.6e-09 35.9 4.9 3.1e-08 33.5 4.9 2.0 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF2722 PF10846.8 CDJ40684.1 - 0.11 11.4 3.0 0.15 11.0 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ40684.1 - 0.11 12.4 10.3 0.13 12.2 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 CDJ40684.1 - 4.2 6.5 20.9 0.031 13.5 12.2 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Activator_LAG-3 PF11498.8 CDJ40685.1 - 1.1 8.2 35.9 0.024 13.6 5.8 3.3 3 0 0 3 3 3 0 Transcriptional activator LAG-3 T2SSM PF04612.12 CDJ40686.1 - 0.11 12.6 3.8 0.14 12.2 3.8 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M SPACA9 PF15120.6 CDJ40686.1 - 0.31 10.8 2.5 0.36 10.6 2.5 1.1 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 DUF1043 PF06295.12 CDJ40687.1 - 0.24 11.4 13.5 1.5 8.9 5.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Ndc1_Nup PF09531.10 CDJ40687.1 - 0.29 9.8 9.2 0.29 9.8 9.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glyco_hydro_9 PF00759.19 CDJ40687.1 - 3.8 6.8 7.2 1.9 7.8 0.9 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 M_domain PF12938.7 CDJ40687.1 - 6 6.6 26.1 0.57 9.9 0.6 2.7 3 0 0 3 3 3 0 M domain of GW182 LAP1C PF05609.12 CDJ40687.1 - 8.5 5.3 14.4 12 4.9 14.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RSRP PF17069.5 CDJ40688.1 - 0.93 9.0 18.9 1.5 8.3 18.9 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 5_3_exonuc_N PF02739.16 CDJ40690.1 - 0.00032 20.6 0.0 0.00046 20.1 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain SUIM_assoc PF16619.5 CDJ40690.1 - 0.77 9.9 7.4 2.4 8.3 7.4 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ40692.1 - 0.045 13.4 3.7 0.051 13.2 3.7 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ40692.1 - 0.064 12.2 1.0 0.067 12.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ40692.1 - 0.15 12.2 7.6 0.22 11.6 7.6 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CLN3 PF02487.17 CDJ40693.1 - 0.17 10.9 1.0 0.26 10.3 1.0 1.3 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 CDJ40693.1 - 1.2 9.1 5.7 1.4 8.9 5.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dsh_C PF12316.8 CDJ40693.1 - 4.8 7.5 17.5 8 6.8 17.5 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RAB3GAP2_N PF14655.6 CDJ40694.1 - 0.02 14.2 3.4 0.022 14.0 3.4 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RskA PF10099.9 CDJ40694.1 - 0.042 14.1 19.5 0.052 13.8 19.5 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CBP_BcsG PF11658.8 CDJ40694.1 - 0.065 11.6 2.3 0.073 11.5 2.3 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Dehydrin PF00257.19 CDJ40694.1 - 0.094 13.3 6.2 0.11 13.0 6.2 1.1 1 0 0 1 1 1 0 Dehydrin TFIIA PF03153.13 CDJ40694.1 - 0.26 11.2 16.0 0.28 11.1 16.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tic110 PF16940.5 CDJ40694.1 - 0.28 9.6 9.7 0.31 9.5 9.7 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Spt20 PF12090.8 CDJ40694.1 - 0.72 9.4 12.9 0.81 9.3 12.9 1.1 1 0 0 1 1 1 0 Spt20 family FAM199X PF15814.5 CDJ40694.1 - 1.5 7.8 7.7 1.8 7.6 7.7 1.1 1 0 0 1 1 1 0 Protein family FAM199X Presenilin PF01080.17 CDJ40694.1 - 1.6 7.4 3.8 1.7 7.3 3.8 1.0 1 0 0 1 1 1 0 Presenilin Roughex PF06020.11 CDJ40694.1 - 3.2 6.8 7.1 3.4 6.7 7.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein MSP1_C PF07462.11 CDJ40694.1 - 4.5 5.8 7.2 5.2 5.6 7.2 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus MCM PF00493.23 CDJ40695.1 - 7.3e-36 123.4 3.4 8e-36 123.2 3.4 1.0 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 CDJ40695.1 - 4.1e-07 29.6 0.0 4.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDJ40695.1 - 0.0013 18.6 0.0 0.0015 18.4 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MinC_C PF03775.16 CDJ40695.1 - 0.016 15.2 0.3 0.026 14.5 0.3 1.4 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain AAA_5 PF07728.14 CDJ40695.1 - 0.083 12.9 0.0 0.12 12.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDJ40695.1 - 0.2 11.8 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DNA_pol_B_palm PF14792.6 CDJ40696.1 - 3.5e-13 49.7 0.0 4.4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase beta palm FAM199X PF15814.5 CDJ40696.1 - 0.069 12.2 0.2 0.077 12.0 0.2 1.0 1 0 0 1 1 1 0 Protein family FAM199X NTP_transf_2 PF01909.23 CDJ40696.1 - 0.095 13.0 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase domain B-block_TFIIIC PF04182.12 CDJ40696.1 - 0.15 12.3 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC SR-25 PF10500.9 CDJ40697.1 - 0.015 14.9 7.7 0.015 14.9 7.7 3.5 3 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein MecA PF05389.12 CDJ40697.1 - 0.22 11.1 2.5 3.5 7.2 1.5 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) ARA70 PF12489.8 CDJ40697.1 - 0.75 10.0 11.6 1.2 9.4 0.1 2.5 2 0 0 2 2 2 0 Nuclear coactivator Macoilin PF09726.9 CDJ40697.1 - 2.7 6.5 12.4 4 5.9 12.4 1.2 1 0 0 1 1 1 0 Macoilin family S36_mt PF10937.8 CDJ40697.1 - 3 9.5 10.5 5.3 8.7 0.2 3.2 3 0 0 3 3 3 0 Ribosomal protein S36, mitochondrial OmpH PF03938.14 CDJ40697.1 - 3 8.2 21.3 0.81 10.0 14.3 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 CDJ40697.1 - 6.3 6.3 14.3 12 5.4 9.5 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Activator_LAG-3 PF11498.8 CDJ40697.1 - 6.7 5.6 25.3 0.46 9.4 20.3 1.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 MutS_V PF00488.21 CDJ40698.1 - 8e-58 195.6 0.2 1.9e-57 194.3 0.2 1.6 1 1 0 1 1 1 1 MutS domain V RskA PF10099.9 CDJ40698.1 - 0.21 11.9 10.9 0.31 11.3 10.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA RLL PF10036.9 CDJ40699.1 - 2.1e-15 57.3 11.5 3e-14 53.5 0.7 2.0 1 1 1 2 2 2 2 RNA transcription, translation and transport factor protein KCNQ2_u3 PF16642.5 CDJ40699.1 - 0.39 11.7 3.9 0.32 12.0 2.6 1.6 1 1 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Roughex PF06020.11 CDJ40699.1 - 3.9 6.5 6.4 4 6.4 6.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 CDJ40699.1 - 7 6.5 14.7 8.3 6.3 14.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rogdi_lz PF10259.9 CDJ40699.1 - 9.3 5.6 9.5 5.2 6.4 1.0 2.0 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein Hid1 PF12722.7 CDJ40701.1 - 1.1e-40 139.6 0.0 1.3e-22 79.8 0.0 2.0 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 CDJ40701.1 - 1.4e-24 86.6 0.0 1.4e-12 46.9 0.0 2.0 1 1 1 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein PBP1_TM PF14812.6 CDJ40702.1 - 0.019 15.3 0.6 0.033 14.5 0.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GREB1 PF15782.5 CDJ40702.1 - 0.16 9.1 12.9 0.17 9.0 12.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Apt1 PF10351.9 CDJ40702.1 - 1.2 7.9 9.4 1.4 7.7 9.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ40702.1 - 2.1 6.8 11.5 2.6 6.5 11.5 1.1 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 CDJ40702.1 - 2.4 5.8 9.2 2.9 5.5 9.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PAP1 PF08601.10 CDJ40702.1 - 3.8 7.2 17.3 5.4 6.6 17.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 SUIM_assoc PF16619.5 CDJ40704.1 - 0.012 15.7 7.3 0.012 15.7 7.3 4.6 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PAP_assoc PF03828.19 CDJ40704.1 - 0.086 13.1 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 Cid1 family poly A polymerase Dynactin_p22 PF07426.11 CDJ40705.1 - 4.2e-11 43.0 3.0 4.2e-11 43.0 3.0 3.8 1 1 1 3 3 3 1 Dynactin subunit p22 PAT1 PF09770.9 CDJ40705.1 - 0.0099 14.2 55.7 0.011 14.0 55.7 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Caldesmon PF02029.15 CDJ40705.1 - 0.017 13.9 41.4 0.024 13.4 41.4 1.3 1 0 0 1 1 1 0 Caldesmon LAP1C PF05609.12 CDJ40705.1 - 0.03 13.4 34.1 0.032 13.3 34.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Dapper PF15268.6 CDJ40705.1 - 0.031 13.1 35.9 0.035 13.0 35.9 1.2 1 0 0 1 1 1 0 Dapper Med15 PF09606.10 CDJ40705.1 - 2.1 6.9 67.0 2.8 6.5 67.0 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SLC12 PF03522.15 CDJ40705.1 - 7.6 5.4 38.9 14 4.6 38.9 1.5 1 0 0 1 1 1 0 Solute carrier family 12 Spt20 PF12090.8 CDJ40706.1 - 6.3 6.3 20.3 0.2 11.2 14.2 1.6 2 0 0 2 2 2 0 Spt20 family DUF1117 PF06547.12 CDJ40706.1 - 8.5 7.0 11.6 1.7 9.2 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1117) Roughex PF06020.11 CDJ40707.1 - 0.048 12.7 3.0 0.066 12.3 3.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein NCOA_u2 PF16665.5 CDJ40707.1 - 0.23 11.8 6.8 0.61 10.4 6.8 1.7 1 0 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein Prenyltransf PF01255.19 CDJ40708.1 - 1e-45 156.0 0.0 1.3e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase SUIM_assoc PF16619.5 CDJ40708.1 - 0.066 13.3 11.8 0.079 13.0 0.6 2.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 UPRTase PF14681.6 CDJ40708.1 - 0.12 11.8 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase TFIIA PF03153.13 CDJ40710.1 - 2e-05 24.8 14.6 2e-05 24.8 14.6 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit AA_permease PF00324.21 CDJ40710.1 - 0.046 12.3 0.1 0.078 11.6 0.1 1.3 1 0 0 1 1 1 0 Amino acid permease Pex14_N PF04695.13 CDJ40710.1 - 0.049 14.3 14.8 0.073 13.7 14.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TRAP_alpha PF03896.16 CDJ40710.1 - 0.13 11.5 1.3 3.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF2370 PF10176.9 CDJ40710.1 - 0.24 11.0 5.2 0.3 10.7 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF5427 PF10310.9 CDJ40710.1 - 0.39 9.6 13.0 0.46 9.4 13.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Otopetrin PF03189.13 CDJ40710.1 - 0.4 9.4 3.8 0.42 9.4 3.8 1.2 1 0 0 1 1 1 0 Otopetrin CSG2 PF16965.5 CDJ40710.1 - 0.41 9.6 5.4 0.59 9.0 5.4 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4175 PF13779.6 CDJ40710.1 - 0.66 7.8 14.4 0.69 7.8 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Macoilin PF09726.9 CDJ40710.1 - 0.89 8.0 17.5 1.1 7.7 17.5 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 CDJ40710.1 - 1.5 8.3 15.4 2.3 7.7 15.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Menin PF05053.13 CDJ40710.1 - 3 6.1 8.9 3.9 5.7 8.9 1.1 1 0 0 1 1 1 0 Menin PNISR PF15996.5 CDJ40710.1 - 3.9 7.7 11.7 5.4 7.2 11.7 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR GREB1 PF15782.5 CDJ40710.1 - 4 4.4 21.3 4.4 4.3 21.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S64 PF08192.11 CDJ40710.1 - 4 5.8 16.9 5 5.5 16.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 THEG4 PF15834.5 CDJ40710.1 - 4.1 7.4 7.6 5.7 6.9 7.6 1.1 1 0 0 1 1 1 0 Testis highly expressed protein 4 DUF1387 PF07139.11 CDJ40710.1 - 4.5 6.9 14.5 5.7 6.6 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) PAT1 PF09770.9 CDJ40710.1 - 5.5 5.1 16.4 6.5 4.9 16.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TMEM52 PF14979.6 CDJ40710.1 - 5.8 6.8 12.9 7 6.6 0.4 2.6 2 1 0 2 2 2 0 Transmembrane 52 Membralin PF09746.9 CDJ40710.1 - 7.2 5.5 7.3 9.2 5.2 7.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Neur_chan_memb PF02932.16 CDJ40710.1 - 7.5 6.5 9.4 11 6.0 9.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hydin_ADK PF17213.3 CDJ40710.1 - 7.6 6.8 18.2 12 6.2 18.2 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Suf PF05843.14 CDJ40710.1 - 8.5 6.3 15.3 11 5.9 15.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SLC12 PF03522.15 CDJ40710.1 - 9.5 5.1 11.4 12 4.8 11.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2722 PF10846.8 CDJ40711.1 - 3.8e-05 22.8 7.8 3.8e-05 22.8 7.8 3.6 3 1 0 4 4 4 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ40711.1 - 0.0066 16.5 12.2 0.0066 16.5 12.2 3.0 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit CTD_bind PF04818.13 CDJ40711.1 - 0.057 14.2 0.1 0.21 12.4 0.1 2.1 1 0 0 1 1 1 0 RNA polymerase II-binding domain. MecA PF05389.12 CDJ40711.1 - 0.78 9.3 16.1 2.4 7.7 2.1 3.1 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) Presenilin PF01080.17 CDJ40711.1 - 3.7 6.2 22.0 4.4 6.0 5.0 2.3 2 0 0 2 2 2 0 Presenilin Maf1 PF09174.10 CDJ40711.1 - 3.8 7.7 0.0 3.8 7.7 0.0 3.8 3 1 0 3 3 3 0 Maf1 regulator DnaJ PF00226.31 CDJ40713.1 - 8.2e-11 41.9 0.2 1.2e-10 41.3 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain SUIM_assoc PF16619.5 CDJ40714.1 - 0.0097 15.9 5.4 0.016 15.3 5.4 1.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 EF-hand_4 PF12763.7 CDJ40714.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Med3 PF11593.8 CDJ40714.1 - 1.5 8.0 8.0 2.1 7.5 8.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Methyltransf_14 PF08484.11 CDJ40715.1 - 0.015 15.1 0.5 12 5.7 0.0 3.1 3 0 0 3 3 3 0 C-methyltransferase C-terminal domain AbiEi_4 PF13338.6 CDJ40715.1 - 0.047 13.8 0.3 0.2 11.8 0.3 2.2 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Abhydrolase_4 PF08386.10 CDJ40715.1 - 0.32 11.1 4.3 8 6.6 0.5 2.6 2 0 0 2 2 2 0 TAP-like protein PDZ_3 PF17815.1 CDJ40717.1 - 3.2e-45 153.6 0.0 6e-45 152.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 CDJ40717.1 - 6.8e-21 75.7 0.4 1.3e-20 74.9 0.4 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CDJ40717.1 - 2e-13 50.6 0.5 3.8e-13 49.8 0.5 1.5 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 CDJ40717.1 - 1.3e-08 35.0 0.1 7.9e-07 29.3 0.0 3.0 3 0 0 3 3 3 1 PDZ domain PDZ_6 PF17820.1 CDJ40717.1 - 1.6e-05 24.7 0.3 0.021 14.6 0.3 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 CDJ40717.1 - 0.0025 18.1 0.0 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 CDJ40717.1 - 0.053 12.2 0.0 0.076 11.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S7 PF00949.21 CDJ40717.1 - 0.07 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease UQ_con PF00179.26 CDJ40718.1 - 4.6e-39 133.3 0.1 6.4e-39 132.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ40718.1 - 0.042 13.5 0.2 0.1 12.3 0.1 1.7 1 1 1 2 2 2 0 Prokaryotic E2 family B DUF3273 PF11677.8 CDJ40719.1 - 1.5e-95 319.5 4.4 1.7e-95 319.3 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF2569 PF10754.9 CDJ40719.1 - 0.16 12.4 5.3 0.29 11.6 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) Tetraspanin PF00335.20 CDJ40719.1 - 5.2 6.7 8.2 62 3.2 5.9 2.9 1 1 1 2 2 2 0 Tetraspanin family DUF948 PF06103.11 CDJ40721.1 - 0.12 12.7 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FeoB_associated PF12669.7 CDJ40721.1 - 0.18 12.3 0.8 0.31 11.5 0.8 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Ribosomal_L3 PF00297.22 CDJ40724.1 - 5e-10 38.9 3.9 3.1e-08 33.0 2.6 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Bromodomain PF00439.25 CDJ40725.1 - 8.4e-22 77.0 0.3 1.9e-21 75.9 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 CDJ40725.1 - 2.5e-11 43.8 0.1 6.2e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ40725.1 - 6.3e-09 35.8 0.1 1.1e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ40725.1 - 7e-07 29.6 0.8 1.5e-06 28.5 0.8 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PCAF_N PF06466.11 CDJ40725.1 - 0.0038 16.8 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Acetyltransf_9 PF13527.7 CDJ40725.1 - 0.011 15.9 0.1 0.06 13.4 0.1 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ40725.1 - 0.011 15.7 0.0 0.032 14.2 0.0 1.9 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 CDJ40725.1 - 0.095 12.8 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PsbQ PF05757.11 CDJ40725.1 - 0.56 9.9 2.0 1.1 8.9 1.5 1.7 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) OST-HTH PF12872.7 CDJ40726.1 - 0.00024 20.9 0.0 0.00055 19.7 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain FH2 PF02181.23 CDJ40727.1 - 1.9e-38 132.6 0.0 6.5e-27 94.6 0.0 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain SET PF00856.28 CDJ40732.1 - 5.9e-20 72.3 0.0 5.9e-20 72.3 0.0 3.5 3 0 0 3 3 3 1 SET domain CDC45 PF02724.14 CDJ40732.1 - 0.81 7.9 7.7 1.6 6.9 7.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Med19 PF10278.9 CDJ40732.1 - 1.6 8.6 6.8 3.3 7.6 6.8 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4746 PF15928.5 CDJ40732.1 - 2.6 7.4 11.7 12 5.3 12.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) NARP1 PF12569.8 CDJ40732.1 - 3.4 6.5 10.8 6.5 5.5 10.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PHF5 PF03660.14 CDJ40733.1 - 5.2e-50 168.0 12.7 6.4e-50 167.7 12.7 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 CDJ40733.1 - 0.22 9.3 7.9 0.24 9.2 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF1077 PF06417.12 CDJ40736.1 - 4.8e-14 52.4 0.0 7e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF3138 PF11336.8 CDJ40736.1 - 0.076 11.6 5.1 0.096 11.3 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4412 PF14371.6 CDJ40737.1 - 0.019 14.8 2.0 0.03 14.1 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4412) VPS13 PF16908.5 CDJ40738.1 - 0.032 14.0 0.4 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CDJ40738.1 - 0.14 12.3 7.0 0.15 12.2 0.1 3.2 3 0 0 3 3 3 0 N-terminal region of Chorein or VPS13 SPX PF03105.19 CDJ40738.1 - 8.2 6.2 20.3 5.8 6.7 5.8 2.5 2 1 0 2 2 2 0 SPX domain Ribosomal_L27 PF01016.19 CDJ40739.1 - 1.1e-11 44.6 0.2 4.7e-11 42.6 0.2 1.8 1 1 0 1 1 1 1 Ribosomal L27 protein KAAG1 PF15354.6 CDJ40739.1 - 1.7 9.3 6.5 2.1 9.0 0.9 3.1 2 1 1 3 3 3 0 Kidney-associated antigen 1 Dynein_light PF01221.18 CDJ40740.1 - 2.6e-21 75.7 0.1 2.9e-21 75.6 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 zf-4CXXC_R1 PF10497.9 CDJ40740.1 - 0.0061 16.8 0.0 0.0064 16.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Sec63 PF02889.16 CDJ40743.1 - 5.2e-20 71.7 0.1 7.3e-20 71.2 0.1 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 CDJ40743.1 - 1.2e-19 70.1 0.4 2.6e-19 69.1 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain Ank_2 PF12796.7 CDJ40744.1 - 5.7e-26 90.9 9.5 8.5e-09 35.9 3.9 4.7 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ40744.1 - 1.1e-24 86.5 13.8 2.4e-08 34.3 1.4 6.5 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ40744.1 - 1.3e-23 82.7 14.0 2.5e-10 40.4 0.2 5.8 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 CDJ40744.1 - 8.8e-23 79.7 18.0 0.00092 19.6 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 CDJ40744.1 - 1.4e-17 62.0 8.6 0.091 13.4 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Sushi PF00084.20 CDJ40744.1 - 3.5e-08 33.9 0.2 7.4e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) DUF4201 PF13870.6 CDJ40745.1 - 3.2e-19 69.3 24.9 3.2e-19 69.3 24.9 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF4201) TFIIA PF03153.13 CDJ40746.1 - 2.1 8.3 10.0 2.9 7.8 10.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ40747.1 - 6.6 6.2 12.9 9.3 5.7 12.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF775 PF05603.12 CDJ40748.1 - 4.2e-15 55.8 0.3 8.6e-06 25.4 0.0 3.4 2 2 0 2 2 2 2 Protein of unknown function (DUF775) Apt1 PF10351.9 CDJ40748.1 - 0.023 13.6 7.8 0.025 13.5 7.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nucleoporin_FG2 PF15967.5 CDJ40748.1 - 0.19 10.2 22.0 0.24 9.9 22.0 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region SPX PF03105.19 CDJ40748.1 - 0.41 10.5 14.0 0.094 12.6 10.5 1.6 2 0 0 2 2 2 0 SPX domain Macoilin PF09726.9 CDJ40748.1 - 0.47 9.0 12.8 0.52 8.8 12.8 1.1 1 0 0 1 1 1 0 Macoilin family CHZ PF09649.10 CDJ40749.1 - 0.064 12.7 0.2 0.23 10.9 0.2 2.0 1 0 0 1 1 1 0 Histone chaperone domain CHZ Macro PF01661.21 CDJ40750.1 - 4.8e-09 36.3 0.1 2.1e-05 24.5 0.0 2.8 3 0 0 3 3 3 2 Macro domain SUIM_assoc PF16619.5 CDJ40750.1 - 0.013 15.5 3.7 0.013 15.5 3.7 5.3 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Myb_DNA-binding PF00249.31 CDJ40751.1 - 6.7e-09 35.8 0.2 1.2e-08 34.9 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ40751.1 - 0.00024 21.3 0.0 0.00075 19.7 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain FAM60A PF15396.6 CDJ40754.1 - 0.27 11.2 7.6 0.45 10.5 7.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.13 CDJ40754.1 - 0.29 11.1 30.4 0.39 10.7 30.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 CDJ40754.1 - 0.52 8.4 21.3 0.67 8.0 21.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PNISR PF15996.5 CDJ40754.1 - 0.71 10.1 28.1 1.6 9.0 28.1 1.5 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR TFIIF_alpha PF05793.12 CDJ40754.1 - 3 6.3 24.5 4.1 5.9 24.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 CDJ40754.1 - 5.2 5.1 23.2 6.8 4.8 23.2 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 CDJ40754.1 - 6.3 5.5 19.7 9.1 4.9 19.7 1.2 1 0 0 1 1 1 0 Presenilin EGF_3 PF12947.7 CDJ40756.1 - 7.5e-07 29.2 56.6 0.00046 20.3 12.7 5.8 5 0 0 5 5 5 4 EGF domain FXa_inhibition PF14670.6 CDJ40756.1 - 0.0093 16.2 70.3 0.025 14.8 8.2 6.0 5 1 1 6 6 6 5 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CDJ40756.1 - 0.13 12.5 64.6 0.53 10.5 12.9 5.8 5 0 0 5 5 5 0 Calcium-binding EGF domain DUF4083 PF13314.6 CDJ40756.1 - 0.17 11.8 0.3 0.38 10.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) cEGF PF12662.7 CDJ40756.1 - 0.8 9.7 45.9 0.12 12.3 3.9 6.0 5 1 0 5 5 5 0 Complement Clr-like EGF-like Nucleoside_tran PF01733.18 CDJ40758.1 - 2.2e-16 60.2 9.2 3.3e-16 59.6 9.2 1.3 1 0 0 1 1 1 1 Nucleoside transporter AT_hook PF02178.19 CDJ40759.1 - 0.71 9.9 6.5 1.9 8.6 6.5 1.8 1 0 0 1 1 1 0 AT hook motif RRM_1 PF00076.22 CDJ40760.1 - 7.1e-08 32.2 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LSM PF01423.22 CDJ40761.1 - 1.3e-15 56.8 0.9 2.3e-15 56.0 0.9 1.4 1 0 0 1 1 1 1 LSM domain IMCp PF12314.8 CDJ40762.1 - 3.2e-31 107.5 89.2 4.2e-20 71.8 38.7 4.2 1 1 2 3 3 3 3 Inner membrane complex protein IMCp PF12314.8 CDJ40763.1 - 1.3e-25 89.5 64.0 3.2e-25 88.3 41.8 4.7 2 2 1 3 3 3 2 Inner membrane complex protein PBAN PF05874.11 CDJ40763.1 - 0.1 12.5 0.4 0.27 11.1 0.4 1.6 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) ALMT PF11744.8 CDJ40763.1 - 4.8 5.9 8.9 3.6 6.3 0.4 2.4 2 0 0 2 2 2 0 Aluminium activated malate transporter PEHE PF15275.6 CDJ40763.1 - 9.7 6.8 14.3 0.17 12.5 0.3 3.1 3 0 0 3 3 3 0 PEHE domain ketoacyl-synt PF00109.26 CDJ40764.1 - 1.2e-299 988.3 8.8 2.9e-79 266.2 0.4 4.8 4 0 0 4 4 4 4 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 CDJ40764.1 - 4.1e-237 779.5 0.1 8.6e-58 195.2 0.0 5.6 6 0 0 6 6 5 4 KR domain PS-DH PF14765.6 CDJ40764.1 - 3.3e-171 568.3 14.1 1.1e-44 152.9 0.1 5.6 5 0 0 5 5 5 5 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 CDJ40764.1 - 5e-160 523.3 13.6 2.8e-40 137.0 0.3 5.1 5 0 0 5 5 4 4 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 CDJ40764.1 - 3.9e-121 404.5 1.6 2.2e-49 168.7 0.1 3.4 3 0 0 3 3 3 3 Acyl transferase domain PP-binding PF00550.25 CDJ40764.1 - 1.4e-67 223.9 1.4 1.6e-12 47.6 0.0 5.8 5 0 0 5 5 5 5 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 CDJ40764.1 - 3.2e-61 205.1 0.4 5.4e-15 55.5 0.0 5.1 5 0 0 5 5 4 4 Zinc-binding dehydrogenase NAD_binding_4 PF07993.12 CDJ40764.1 - 1.2e-54 185.2 0.0 3e-52 177.4 0.0 3.6 4 0 0 4 4 4 1 Male sterility protein adh_short PF00106.25 CDJ40764.1 - 3.2e-50 170.3 0.0 3.9e-12 46.1 0.0 5.6 4 0 0 4 4 4 4 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 CDJ40764.1 - 5.6e-45 153.6 0.0 7.3e-09 36.8 0.0 6.6 5 0 0 5 5 5 4 Zinc-binding dehydrogenase Sulfotransfer_3 PF13469.6 CDJ40764.1 - 3.6e-42 145.2 0.1 8.1e-42 144.0 0.1 1.7 1 0 0 1 1 1 1 Sulfotransferase family KAsynt_C_assoc PF16197.5 CDJ40764.1 - 2.6e-35 121.3 0.0 4.8e-08 33.4 0.0 4.8 4 0 0 4 4 4 4 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 CDJ40764.1 - 1.3e-33 116.4 0.0 5.5e-07 29.3 0.0 5.5 5 0 0 5 5 5 5 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 CDJ40764.1 - 6.6e-32 110.9 0.0 6.6e-07 29.1 0.0 4.7 4 0 0 4 4 4 4 Enoyl-(Acyl carrier protein) reductase AMP-binding PF00501.28 CDJ40764.1 - 1.4e-26 93.1 0.0 9e-26 90.4 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme ADH_N PF08240.12 CDJ40764.1 - 8.7e-22 77.1 13.8 2.8e-05 24.0 0.1 6.6 7 0 0 7 7 6 4 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 CDJ40764.1 - 4.3e-18 65.6 6.9 0.00051 19.5 0.3 4.9 4 0 0 4 4 4 4 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 CDJ40764.1 - 1.1e-17 64.0 0.0 0.0042 16.1 0.0 5.4 5 0 0 5 5 5 4 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CDJ40764.1 - 4.1e-16 59.0 0.0 0.0045 16.1 0.0 4.9 5 0 0 5 5 5 4 Polysaccharide biosynthesis protein Sulfotransfer_1 PF00685.27 CDJ40764.1 - 1.7e-15 57.2 0.3 3e-15 56.4 0.3 1.3 1 0 0 1 1 1 1 Sulfotransferase domain GDP_Man_Dehyd PF16363.5 CDJ40764.1 - 2.1e-11 43.8 0.0 0.44 9.9 0.0 5.6 5 0 0 5 5 5 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CDJ40764.1 - 1.3e-05 25.2 0.1 25 4.7 0.0 5.2 5 0 0 5 5 4 0 NAD(P)H-binding AlaDh_PNT_C PF01262.21 CDJ40764.1 - 2.9e-05 23.5 11.6 0.54 9.5 0.3 4.6 4 0 0 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 CDJ40764.1 - 0.0014 18.4 2.5 9.5 5.8 0.0 4.9 5 0 0 5 5 4 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 4HB PF17947.1 CDJ40764.1 - 0.0041 17.1 0.1 1.1 9.3 0.0 3.2 3 0 0 3 3 2 1 Four helical bundle domain SAT PF16073.5 CDJ40764.1 - 0.0041 16.9 6.0 0.53 10.0 0.0 4.1 3 2 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Shikimate_DH PF01488.20 CDJ40764.1 - 0.0076 16.3 0.2 58 3.7 0.0 3.8 4 0 0 4 4 3 0 Shikimate / quinate 5-dehydrogenase Sulfotransfer_4 PF17784.1 CDJ40764.1 - 0.016 15.0 0.6 0.066 13.0 0.1 2.3 2 0 0 2 2 2 0 Sulfotransferase domain AMP-binding_C_2 PF14535.6 CDJ40764.1 - 0.017 15.4 0.0 0.058 13.7 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain FabA PF07977.13 CDJ40764.1 - 0.066 12.8 0.0 0.3 10.7 0.0 2.1 1 0 0 1 1 1 0 FabA-like domain ACP_syn_III PF08545.10 CDJ40764.1 - 0.07 13.0 25.3 0.68 9.8 0.5 5.9 5 1 0 5 5 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ApbA PF02558.16 CDJ40764.1 - 5 6.7 4.9 6 6.5 0.3 3.5 4 0 0 4 4 4 0 Ketopantoate reductase PanE/ApbA AMP-binding PF00501.28 CDJ40765.1 - 1.8e-33 115.8 0.0 4.6e-33 114.4 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Thioredoxin PF00085.20 CDJ40767.1 - 0.0019 18.1 0.1 0.0027 17.7 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CDJ40767.1 - 0.0026 17.7 0.0 0.0031 17.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Rad10 PF03834.14 CDJ40768.1 - 2.5e-24 85.5 0.0 5.1e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) V_ATPase_I PF01496.19 CDJ40768.1 - 7.6e-05 20.8 11.8 8.9e-05 20.6 11.8 1.4 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Ndc1_Nup PF09531.10 CDJ40768.1 - 0.0093 14.7 21.0 0.012 14.4 21.0 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup HHH_5 PF14520.6 CDJ40768.1 - 0.01 16.4 0.0 0.023 15.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH PF00633.23 CDJ40768.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_2 PF12826.7 CDJ40768.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Mem_trans PF03547.18 CDJ40768.1 - 0.21 10.0 1.3 0.25 9.7 1.3 1.3 1 0 0 1 1 1 0 Membrane transport protein Pkinase_fungal PF17667.1 CDJ40768.1 - 0.24 10.2 12.4 0.36 9.6 12.4 1.3 1 0 0 1 1 1 0 Fungal protein kinase VIT1 PF01988.19 CDJ40768.1 - 0.4 10.5 8.6 1.2 9.0 8.6 1.9 1 0 0 1 1 1 0 VIT family Endostatin PF06482.11 CDJ40768.1 - 1.2 8.5 27.9 1.9 7.9 27.9 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Presenilin PF01080.17 CDJ40768.1 - 2 7.1 38.4 3.1 6.5 38.4 1.2 1 0 0 1 1 1 0 Presenilin DUF763 PF05559.11 CDJ40768.1 - 4.7 6.3 16.6 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF763) DUF2877 PF11392.8 CDJ40768.1 - 6.1 7.6 0.0 6.1 7.6 0.0 3.4 2 2 1 3 3 2 0 Protein of unknown function (DUF2877) Otopetrin PF03189.13 CDJ40768.1 - 6.4 5.5 19.1 37 3.0 19.6 1.8 1 1 0 1 1 1 0 Otopetrin PIEZO PF15917.5 CDJ40768.1 - 6.6 6.1 35.4 12 5.2 35.4 1.5 1 0 0 1 1 1 0 Piezo Glycolytic PF00274.19 CDJ40769.1 - 6.7e-168 557.8 0.0 7.5e-168 557.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Pkinase PF00069.25 CDJ40770.1 - 1e-47 162.7 6.1 4.8e-33 114.6 0.0 3.1 4 0 0 4 4 4 2 Protein kinase domain YueH PF14166.6 CDJ40770.1 - 6.3 6.7 6.6 3.8 7.4 0.0 3.7 3 0 0 3 3 3 0 YueH-like protein LSM PF01423.22 CDJ40771.1 - 8.9e-19 67.0 0.0 1.1e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.13 CDJ40772.1 - 1.1e-12 48.0 0.5 2e-11 44.0 0.2 2.0 1 1 1 2 2 2 2 Mitochondrial pyruvate carriers Herpes_pp85 PF04637.12 CDJ40772.1 - 0.13 10.7 0.9 0.14 10.6 0.9 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SR-25 PF10500.9 CDJ40772.1 - 1.7 8.2 10.4 1.9 8.0 10.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BASP1 PF05466.12 CDJ40773.1 - 0.0064 16.6 46.7 0.0064 16.6 46.7 1.6 2 0 0 2 2 2 1 Brain acid soluble protein 1 (BASP1 protein) SPX PF03105.19 CDJ40773.1 - 0.31 10.9 5.3 0.41 10.5 5.3 1.2 1 0 0 1 1 1 0 SPX domain Mitofilin PF09731.9 CDJ40773.1 - 3.3 6.4 17.0 5 5.8 17.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Spt20 PF12090.8 CDJ40773.1 - 4.3 6.9 22.3 3.3 7.2 12.7 2.2 2 0 0 2 2 2 0 Spt20 family Leu_zip PF15294.6 CDJ40774.1 - 0.018 14.6 1.2 0.018 14.6 1.2 2.1 1 1 0 2 2 2 0 Leucine zipper PROCN PF08083.11 CDJ40776.1 - 1.5e-230 764.9 6.2 2.2e-230 764.4 6.2 1.2 1 0 0 1 1 1 1 PROCN (NUC071) domain U6-snRNA_bdg PF10596.9 CDJ40776.1 - 6.9e-86 286.1 2.4 1.5e-85 285.0 2.4 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CDJ40776.1 - 2.6e-82 274.2 0.3 6.6e-82 272.9 0.3 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CDJ40776.1 - 5.5e-72 240.1 0.0 1e-71 239.3 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 CDJ40776.1 - 4e-46 155.3 0.1 8.5e-46 154.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Planc_extracel PF07595.12 CDJ40776.1 - 6.5 6.7 6.4 0.74 9.7 0.2 2.9 2 0 0 2 2 2 0 Planctomycete extracellular SARAF PF06682.12 CDJ40776.1 - 7.6 6.1 10.1 13 5.4 10.1 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SOG2 PF10428.9 CDJ40777.1 - 7.4 5.6 16.3 9.1 5.3 16.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SR-25 PF10500.9 CDJ40779.1 - 0.0014 18.3 18.1 0.0014 18.3 16.5 1.6 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ40779.1 - 1.3 7.8 9.8 1.7 7.4 9.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 CDJ40779.1 - 2.9 6.5 12.0 3.4 6.3 12.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF755 PF05501.11 CDJ40779.1 - 3.7 7.8 27.3 0.12 12.6 19.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF4692 PF15763.5 CDJ40779.1 - 4.7 7.7 10.1 8.4 6.8 10.1 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Spt20 PF12090.8 CDJ40779.1 - 4.7 6.8 24.2 4.1 6.9 14.4 2.1 2 0 0 2 2 2 0 Spt20 family SLC12 PF03522.15 CDJ40779.1 - 4.8 6.1 6.4 6.4 5.7 6.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF702 PF05142.12 CDJ40779.1 - 6.4 7.2 9.2 0.93 10.0 4.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Macoilin PF09726.9 CDJ40779.1 - 7.8 4.9 9.0 9.8 4.6 9.0 1.1 1 0 0 1 1 1 0 Macoilin family TERB2 PF15101.6 CDJ40779.1 - 9.3 6.2 10.1 13 5.8 7.6 1.9 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Fis1_TPR_N PF14852.6 CDJ40781.1 - 1.7e-06 27.6 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat Ntox1 PF15500.6 CDJ40781.1 - 0.17 12.2 0.1 0.3 11.5 0.1 1.4 1 1 0 1 1 1 0 Putative RNase-like toxin, toxin_1 RIO1 PF01163.22 CDJ40782.1 - 7.7e-12 45.2 0.0 7.9e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 RIO1 family CDC45 PF02724.14 CDJ40784.1 - 0.00025 19.5 6.4 0.00025 19.5 6.4 1.4 2 0 0 2 2 2 1 CDC45-like protein DUF2052 PF09747.9 CDJ40784.1 - 0.019 15.1 24.2 0.03 14.5 24.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RIFIN PF02009.16 CDJ40784.1 - 0.044 13.7 6.8 0.06 13.2 6.8 1.2 1 0 0 1 1 1 0 Rifin Connexin PF00029.19 CDJ40784.1 - 0.053 13.3 7.4 0.081 12.7 7.4 1.3 1 0 0 1 1 1 0 Connexin VIR_N PF15912.5 CDJ40784.1 - 0.19 11.3 15.5 0.26 10.9 15.5 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal LAP1C PF05609.12 CDJ40784.1 - 0.26 10.3 17.2 0.33 10.0 17.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RR_TM4-6 PF06459.12 CDJ40784.1 - 0.3 10.9 18.5 0.42 10.4 18.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 CDJ40784.1 - 0.4 8.5 14.8 0.51 8.2 14.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4471 PF14740.6 CDJ40784.1 - 0.46 9.7 9.8 0.7 9.1 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Ndc1_Nup PF09531.10 CDJ40784.1 - 0.51 9.0 15.0 0.57 8.8 15.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CCSAP PF15748.5 CDJ40784.1 - 0.63 10.2 22.6 0.89 9.7 22.6 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Bul1_C PF04426.12 CDJ40784.1 - 0.64 9.4 12.5 0.93 8.9 12.5 1.1 1 0 0 1 1 1 0 Bul1 C terminus SID-1_RNA_chan PF13965.6 CDJ40784.1 - 0.64 8.4 3.1 0.69 8.3 3.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TT_ORF1 PF02956.14 CDJ40784.1 - 0.76 8.4 9.5 0.26 9.9 7.2 1.3 2 0 0 2 2 2 0 TT viral orf 1 DUF4746 PF15928.5 CDJ40784.1 - 1.2 8.5 21.4 1.7 8.0 21.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) HCO3_cotransp PF00955.21 CDJ40784.1 - 1.3 7.8 4.8 1.7 7.4 4.8 1.1 1 0 0 1 1 1 0 HCO3- transporter family Peptidase_S64 PF08192.11 CDJ40784.1 - 1.3 7.4 10.0 1.5 7.2 10.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 GAGA_bind PF06217.12 CDJ40784.1 - 1.4 9.1 12.4 1.8 8.8 12.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SART-1 PF03343.13 CDJ40784.1 - 1.5 7.3 25.6 2 6.8 25.6 1.1 1 0 0 1 1 1 0 SART-1 family Het-C PF07217.11 CDJ40784.1 - 1.6 7.1 16.4 2.2 6.7 16.4 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Band_3_cyto PF07565.13 CDJ40784.1 - 1.9 8.2 12.7 3.2 7.5 12.7 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SLC12 PF03522.15 CDJ40784.1 - 1.9 7.4 18.4 2.7 6.9 18.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Asp-B-Hydro_N PF05279.11 CDJ40784.1 - 2.5 8.1 23.7 3.5 7.6 23.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HAUS6_N PF14661.6 CDJ40784.1 - 2.5 7.6 20.1 4.1 6.9 20.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2347 PF09804.9 CDJ40784.1 - 2.9 7.4 8.1 4.1 6.9 8.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) SpoIIP PF07454.11 CDJ40784.1 - 3.4 7.0 19.7 5.7 6.3 19.7 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ40784.1 - 3.8 6.4 18.6 4.8 6.0 18.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SAPS PF04499.15 CDJ40784.1 - 4.1 6.1 20.0 5.9 5.6 20.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MDM10 PF12519.8 CDJ40784.1 - 4.1 6.1 13.1 5.2 5.8 13.1 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 LMBR1 PF04791.16 CDJ40784.1 - 4.4 6.1 10.0 5.8 5.7 10.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CSG2 PF16965.5 CDJ40784.1 - 4.6 6.1 6.9 6.1 5.7 6.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator ALMT PF11744.8 CDJ40784.1 - 5.3 5.8 13.4 7.1 5.3 13.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 CDJ40784.1 - 5.9 5.0 36.2 8 4.6 36.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Membralin PF09746.9 CDJ40784.1 - 6.1 5.8 10.1 8.1 5.4 10.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein Hid1 PF12722.7 CDJ40784.1 - 8.8 4.3 16.8 10 4.1 16.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAST_1 PF06743.15 CDJ40785.1 - 0.018 15.0 0.5 10 6.2 0.2 3.3 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Glt_symporter PF03616.14 CDJ40785.1 - 0.029 13.1 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF2722 PF10846.8 CDJ40785.1 - 0.071 12.1 1.3 0.078 11.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ40785.1 - 0.51 9.9 7.2 0.75 9.4 7.2 1.2 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ40785.1 - 2.9 6.8 15.7 4.1 6.3 15.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ribosomal_60s PF00428.19 CDJ40785.1 - 3.1 8.4 10.2 12 6.5 10.2 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein EPL1 PF10513.9 CDJ40786.1 - 0.0051 17.2 7.3 0.0062 16.9 7.3 1.4 1 0 0 1 1 1 1 Enhancer of polycomb-like CPSF100_C PF13299.6 CDJ40786.1 - 0.0069 16.6 10.8 0.0089 16.2 10.8 1.2 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 CDJ40786.1 - 0.011 15.9 7.3 0.011 15.9 7.3 1.1 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.9 CDJ40786.1 - 0.014 13.7 19.2 0.015 13.6 19.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.9 CDJ40786.1 - 0.018 14.6 12.9 0.023 14.3 12.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF5523 PF17661.1 CDJ40786.1 - 0.03 14.0 13.4 0.035 13.8 13.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) SpoIIP PF07454.11 CDJ40786.1 - 0.037 13.5 11.3 0.041 13.3 11.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Nop53 PF07767.11 CDJ40786.1 - 0.046 13.1 18.8 0.055 12.9 18.8 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GBP_C PF02841.14 CDJ40786.1 - 0.048 13.1 16.7 0.053 12.9 16.7 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain eIF3_subunit PF08597.10 CDJ40786.1 - 0.21 11.5 17.3 0.26 11.2 17.3 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SAPS PF04499.15 CDJ40786.1 - 0.25 10.1 10.5 0.27 10.0 10.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIA PF03153.13 CDJ40786.1 - 0.25 11.3 34.6 0.29 11.1 34.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.6 CDJ40786.1 - 0.29 11.6 17.6 0.38 11.2 17.6 1.2 1 0 0 1 1 1 0 AAA domain CCSAP PF15748.5 CDJ40786.1 - 0.37 10.9 20.4 0.47 10.6 20.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF3391 PF11871.8 CDJ40786.1 - 0.53 10.8 14.6 0.8 10.2 14.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Tim54 PF11711.8 CDJ40786.1 - 0.69 8.6 11.4 0.82 8.4 11.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Rxt3 PF08642.10 CDJ40786.1 - 0.69 10.7 5.0 0.94 10.3 5.0 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Sec62 PF03839.16 CDJ40786.1 - 0.71 9.3 7.0 0.79 9.2 7.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Cyto_heme_lyase PF01265.17 CDJ40786.1 - 0.73 9.4 14.2 0.91 9.1 14.2 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Ndc1_Nup PF09531.10 CDJ40786.1 - 0.83 8.3 13.2 0.82 8.3 13.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex26 PF07163.12 CDJ40786.1 - 0.86 8.8 10.5 1.1 8.5 10.5 1.2 1 0 0 1 1 1 0 Pex26 protein Isy1 PF06246.12 CDJ40786.1 - 0.87 9.1 15.9 0.98 8.9 15.9 1.1 1 0 0 1 1 1 0 Isy1-like splicing family RabGAP-TBC PF00566.18 CDJ40786.1 - 1 8.9 9.8 1.4 8.5 9.8 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain EIIBC-GUT_N PF03612.14 CDJ40786.1 - 1.1 9.0 10.9 1.5 8.5 10.9 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SMYLE_N PF18615.1 CDJ40786.1 - 1.2 8.6 12.0 1.3 8.5 12.0 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Endostatin PF06482.11 CDJ40786.1 - 1.5 8.2 13.6 1.9 7.9 13.6 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Lin-8 PF03353.15 CDJ40786.1 - 1.6 8.2 20.3 2.2 7.7 20.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Connexin PF00029.19 CDJ40786.1 - 1.6 8.4 8.5 1.9 8.2 8.5 1.1 1 0 0 1 1 1 0 Connexin RR_TM4-6 PF06459.12 CDJ40786.1 - 1.7 8.4 18.1 2 8.2 18.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Plasmodium_Vir PF05795.11 CDJ40786.1 - 2 7.8 9.1 2.4 7.5 9.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein XAP5 PF04921.14 CDJ40786.1 - 2.1 8.1 11.1 2.7 7.7 11.1 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator GRA6 PF05084.13 CDJ40786.1 - 2.3 8.1 12.4 2.9 7.8 12.4 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Exonuc_VII_L PF02601.15 CDJ40786.1 - 2.4 7.7 13.6 2.9 7.4 13.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CLN3 PF02487.17 CDJ40786.1 - 2.4 7.1 9.3 2.9 6.8 9.3 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4407 PF14362.6 CDJ40786.1 - 2.6 7.3 13.5 3 7.1 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 CDJ40786.1 - 2.7 6.7 19.5 2.8 6.6 19.5 1.1 1 0 0 1 1 1 0 Presenilin Membralin PF09746.9 CDJ40786.1 - 2.7 7.0 5.8 2.9 6.8 5.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein Folate_carrier PF01770.18 CDJ40786.1 - 2.7 6.6 6.7 3.2 6.4 6.7 1.1 1 0 0 1 1 1 0 Reduced folate carrier SOBP PF15279.6 CDJ40786.1 - 2.8 8.4 17.0 3.2 8.3 17.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF5521 PF17659.1 CDJ40786.1 - 3.2 5.5 9.0 4 5.2 9.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) CSG2 PF16965.5 CDJ40786.1 - 3.7 6.4 6.4 4.1 6.2 6.4 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator eIF-3_zeta PF05091.12 CDJ40786.1 - 3.7 6.4 18.5 4.1 6.3 18.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Paf1 PF03985.13 CDJ40786.1 - 4 6.4 19.4 5.7 5.8 19.4 1.3 1 0 0 1 1 1 0 Paf1 Gti1_Pac2 PF09729.9 CDJ40786.1 - 4.1 7.5 13.1 5.4 7.1 13.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family PepSY_TM PF03929.16 CDJ40786.1 - 4.2 6.9 4.8 4.6 6.8 4.8 1.2 1 0 0 1 1 1 0 PepSY-associated TM region DUF2828 PF11443.8 CDJ40786.1 - 4.3 5.3 11.4 5.3 5.0 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) TCP PF03634.13 CDJ40786.1 - 4.4 7.8 16.4 5.5 7.5 16.4 1.2 1 0 0 1 1 1 0 TCP family transcription factor EOS1 PF12326.8 CDJ40786.1 - 4.6 7.1 6.2 6.1 6.7 6.2 1.2 1 0 0 1 1 1 0 N-glycosylation protein OATP PF03137.20 CDJ40786.1 - 4.8 5.4 6.8 5.5 5.1 6.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Tho2 PF11262.8 CDJ40786.1 - 5 6.2 10.5 6 6.0 10.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Peptidase_S64 PF08192.11 CDJ40786.1 - 5.1 5.5 14.5 5.7 5.3 14.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 SLC12 PF03522.15 CDJ40786.1 - 5.3 6.0 14.5 5.5 5.9 14.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FHIPEP PF00771.20 CDJ40786.1 - 5.3 5.4 11.5 6.4 5.1 11.5 1.0 1 0 0 1 1 1 0 FHIPEP family WASH-7_C PF14746.6 CDJ40786.1 - 6 6.5 13.7 11 5.7 13.7 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal V_ATPase_I PF01496.19 CDJ40786.1 - 6 4.6 12.1 6.7 4.5 12.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Raftlin PF15250.6 CDJ40786.1 - 6.1 5.5 16.2 6.8 5.3 16.2 1.0 1 0 0 1 1 1 0 Raftlin ORC_WH_C PF18137.1 CDJ40786.1 - 6.1 6.9 13.5 9.7 6.3 13.5 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Pannexin_like PF12534.8 CDJ40786.1 - 6.3 5.8 8.4 7.1 5.6 8.4 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 G0-G1_switch_2 PF15103.6 CDJ40786.1 - 6.5 7.2 9.9 11 6.5 9.9 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 Med15 PF09606.10 CDJ40786.1 - 6.5 5.3 30.4 2.2 6.9 28.4 1.2 2 0 0 2 2 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TP53IP5 PF15331.6 CDJ40786.1 - 6.9 6.7 12.0 9.1 6.4 12.0 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 MDM10 PF12519.8 CDJ40786.1 - 7.1 5.4 10.7 8.2 5.2 10.7 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 MDM31_MDM32 PF08118.11 CDJ40786.1 - 7.4 5.1 7.4 8.7 4.9 7.4 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins UPF0560 PF10577.9 CDJ40786.1 - 7.9 4.8 17.3 8.8 4.7 17.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Suf PF05843.14 CDJ40786.1 - 8.3 6.3 20.4 9.6 6.1 20.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GREB1 PF15782.5 CDJ40786.1 - 8.6 3.3 17.7 8.9 3.3 17.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GCFC PF07842.12 CDJ40787.1 - 5.5e-11 42.6 2.9 1.4e-10 41.2 0.5 2.1 2 0 0 2 2 2 2 GC-rich sequence DNA-binding factor-like protein UCR_14kD PF02271.16 CDJ40789.1 - 1.6 8.7 8.3 1.2 9.2 1.6 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit EutN_CcmL PF03319.13 CDJ40790.1 - 0.16 12.6 0.0 0.4 11.3 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome Serinc PF03348.15 CDJ40790.1 - 4.8 6.0 5.6 6.8 5.5 5.6 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Activator_LAG-3 PF11498.8 CDJ40790.1 - 5.4 5.9 76.1 0.32 9.9 47.8 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DEAD PF00270.29 CDJ40791.1 - 0.014 15.2 0.4 0.062 13.1 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF4805 PF16063.5 CDJ40792.1 - 1.1 8.5 9.3 1.3 8.3 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Ashwin PF15323.6 CDJ40792.1 - 6.5 6.7 6.8 7.1 6.6 6.8 1.0 1 0 0 1 1 1 0 Developmental protein DUF2057 PF09829.9 CDJ40792.1 - 7.3 6.7 11.5 8.9 6.4 11.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) PI3K_1B_p101 PF10486.9 CDJ40792.1 - 9.2 3.9 7.0 9.5 3.9 7.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RIFIN PF02009.16 CDJ40792.1 - 9.5 6.0 7.7 11 5.8 7.7 1.0 1 0 0 1 1 1 0 Rifin RAP1 PF07218.11 CDJ40793.1 - 5.9 5.0 6.8 12 4.1 6.8 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAP1 PF08601.10 CDJ40793.1 - 8.4 6.0 25.4 0.46 10.2 17.4 2.0 1 1 1 2 2 2 0 Transcription factor PAP1 SR-25 PF10500.9 CDJ40793.1 - 9.6 5.7 37.9 0.08 12.5 24.0 3.0 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein DUF4207 PF13904.6 CDJ40795.1 - 0.0064 16.2 6.6 0.0074 16.0 6.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) PRAS PF15798.5 CDJ40795.1 - 0.041 14.5 0.2 0.082 13.5 0.2 1.5 1 0 0 1 1 1 0 Proline-rich AKT1 substrate 1 Mito_carr PF00153.27 CDJ40795.1 - 0.12 12.3 2.8 5.7 6.9 2.8 2.7 1 1 0 1 1 1 0 Mitochondrial carrier protein TFIIA PF03153.13 CDJ40795.1 - 1.7 8.6 15.7 2 8.3 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM165 PF14981.6 CDJ40795.1 - 4.1 7.3 10.8 0.17 11.7 3.8 2.1 1 1 1 2 2 2 0 FAM165 family AP2 PF00847.20 CDJ40797.1 - 3.1e-07 30.5 0.1 6e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 AP2 domain IrmA PF18673.1 CDJ40797.1 - 0.032 14.4 0.2 0.038 14.1 0.2 1.2 1 0 0 1 1 1 0 interleukin receptor mimic protein A SUIM_assoc PF16619.5 CDJ40797.1 - 0.032 14.3 7.9 0.046 13.8 7.9 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ40798.1 - 0.0002 20.4 0.2 0.0002 20.4 0.2 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) DUF4799 PF16056.5 CDJ40798.1 - 0.0039 16.4 1.0 0.011 15.0 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4799) TFIIA PF03153.13 CDJ40798.1 - 0.1 12.6 13.9 0.13 12.2 8.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ40798.1 - 0.6 10.0 3.3 0.32 10.9 1.0 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Med15 PF09606.10 CDJ40798.1 - 1 8.0 16.1 0.26 9.9 9.8 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ40798.1 - 2.2 7.8 17.3 1.7 8.2 11.3 2.1 2 0 0 2 2 2 0 Spt20 family Vps36-NZF-N PF16988.5 CDJ40799.1 - 0.001 18.5 2.2 0.0085 15.5 0.1 3.6 2 1 1 3 3 3 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain SPX PF03105.19 CDJ40799.1 - 0.19 11.6 59.8 0.11 12.4 5.2 3.4 3 0 0 3 3 3 0 SPX domain RskA PF10099.9 CDJ40801.1 - 0.0006 20.2 46.0 0.025 14.9 2.1 3.4 1 1 2 3 3 3 2 Anti-sigma-K factor rskA RAP1 PF07218.11 CDJ40801.1 - 1.1 7.5 5.6 1.8 6.8 5.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) WBP-1 PF11669.8 CDJ40802.1 - 0.028 15.0 0.9 0.028 15.0 0.9 2.0 1 1 1 2 2 2 0 WW domain-binding protein 1 TFIIA PF03153.13 CDJ40802.1 - 0.35 10.8 9.9 0.49 10.3 9.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ApoL PF05461.11 CDJ40803.1 - 0.12 11.7 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Apolipoprotein L T7SS_ESX_EspC PF10824.8 CDJ40803.1 - 0.27 11.7 3.7 0.59 10.6 3.7 1.4 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm TFIIA PF03153.13 CDJ40804.1 - 0.0019 18.3 9.8 0.0019 18.3 9.8 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ40804.1 - 0.0039 17.7 18.8 0.26 11.9 14.3 2.6 2 0 0 2 2 2 2 60s Acidic ribosomal protein Staufen_C PF16482.5 CDJ40804.1 - 0.0066 16.6 1.6 0.0096 16.1 0.0 2.1 2 1 0 2 2 2 1 Staufen C-terminal domain SUIM_assoc PF16619.5 CDJ40804.1 - 0.025 14.6 5.5 0.025 14.6 5.5 3.8 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DNA_pol3_gamma3 PF12169.8 CDJ40804.1 - 0.32 10.9 7.9 0.57 10.1 7.9 1.4 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III CSG2 PF16965.5 CDJ40804.1 - 0.59 9.0 3.4 2.5 7.0 0.4 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator TSA PF03249.13 CDJ40804.1 - 9.9 4.8 10.0 16 4.2 10.0 1.2 1 0 0 1 1 1 0 Type specific antigen PFK PF00365.20 CDJ40806.1 - 0.15 11.3 0.4 0.84 8.9 0.0 2.2 3 1 1 4 4 4 0 Phosphofructokinase RskA PF10099.9 CDJ40807.1 - 0.24 11.7 7.1 0.24 11.7 7.1 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA RNA_pol_A_bac PF01000.26 CDJ40808.1 - 5.2e-16 59.0 0.0 3.5e-14 53.1 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain SUIM_assoc PF16619.5 CDJ40809.1 - 0.0048 16.9 7.7 0.0048 16.9 7.7 2.2 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 CDK2AP PF09806.9 CDJ40809.1 - 0.0055 16.8 12.6 0.0086 16.2 12.6 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein DUF4366 PF14283.6 CDJ40809.1 - 0.033 14.2 0.3 0.041 13.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RSF PF14876.6 CDJ40809.1 - 0.51 9.2 3.4 0.57 9.1 3.4 1.1 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator DUF3138 PF11336.8 CDJ40809.1 - 0.81 8.2 11.8 1.1 7.8 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Phostensin_N PF13916.6 CDJ40809.1 - 1.3 9.4 8.0 3.3 8.1 8.0 1.7 1 1 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Atrophin-1 PF03154.15 CDJ40809.1 - 1.8 6.7 14.1 2.1 6.5 14.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family Dsh_C PF12316.8 CDJ40809.1 - 2.3 8.6 16.8 2.7 8.4 16.8 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal MFMR_assoc PF16596.5 CDJ40809.1 - 5.8 7.4 16.4 7.3 7.1 16.4 1.2 1 0 0 1 1 1 0 Disordered region downstream of MFMR Roughex PF06020.11 CDJ40809.1 - 6.5 5.7 12.7 1.5 7.8 9.6 1.4 1 1 1 2 2 2 0 Drosophila roughex protein YajC PF02699.15 CDJ40809.1 - 8.9 6.3 6.5 15 5.6 6.5 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit DUF2052 PF09747.9 CDJ40810.1 - 0.19 11.9 15.8 0.013 15.7 7.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PRC2_HTH_1 PF18118.1 CDJ40810.1 - 0.25 12.2 5.5 0.18 12.6 0.9 2.7 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain Renin_r PF07850.14 CDJ40810.1 - 0.32 11.6 0.2 0.32 11.6 0.2 2.3 1 1 1 2 2 2 0 Renin receptor-like protein eIF_4EBP PF05456.11 CDJ40810.1 - 0.87 9.5 12.1 0.1 12.5 5.0 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PAT1 PF09770.9 CDJ40810.1 - 0.87 7.8 20.2 1.1 7.5 20.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4834 PF16118.5 CDJ40810.1 - 1.8 9.6 11.0 40 5.3 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ARF7EP_C PF14949.6 CDJ40810.1 - 6 7.5 10.1 1.2 9.8 1.2 3.0 3 0 0 3 3 3 0 ARF7 effector protein C-terminus TFIIA PF03153.13 CDJ40811.1 - 0.0041 17.2 10.8 0.0041 17.2 10.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ40811.1 - 0.072 11.8 4.7 0.082 11.7 4.7 1.1 1 0 0 1 1 1 0 Presenilin PRC2_HTH_1 PF18118.1 CDJ40811.1 - 0.13 13.1 1.8 0.17 12.7 0.4 1.7 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain VKG_Carbox PF05090.14 CDJ40811.1 - 0.37 9.6 0.3 0.49 9.2 0.3 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase DUF4199 PF13858.6 CDJ40811.1 - 0.82 10.0 1.8 1.2 9.5 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) ANAPC_CDC26 PF10471.9 CDJ40811.1 - 1.2 10.0 20.2 1.7 9.5 16.9 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF4834 PF16118.5 CDJ40811.1 - 1.9 9.5 9.5 3 8.9 7.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Cupin_1 PF00190.22 CDJ40812.1 - 2.9e-07 30.2 0.0 3.3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 CDJ40812.1 - 2.4e-06 27.2 0.0 3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CDJ40812.1 - 0.00059 19.7 0.0 0.00078 19.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.7 CDJ40812.1 - 0.0094 15.7 0.7 0.011 15.5 0.7 1.1 1 0 0 1 1 1 1 Cupin 3-HAO PF06052.12 CDJ40812.1 - 0.019 14.6 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Adeno_PIX PF03955.14 CDJ40812.1 - 0.1 12.8 0.5 0.1 12.8 0.5 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Spt20 PF12090.8 CDJ40813.1 - 1.3 8.6 32.0 3.5 7.2 4.0 4.1 4 0 0 4 4 4 0 Spt20 family Ribosomal_60s PF00428.19 CDJ40814.1 - 4.3 8.0 10.9 12 6.5 0.9 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein RRM_1 PF00076.22 CDJ40816.1 - 8.8e-07 28.7 0.1 1.3e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ40816.1 - 0.048 13.5 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF3720 PF12517.8 CDJ40817.1 - 6.8e-05 23.7 4.4 8.3e-05 23.5 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3720) SET PF00856.28 CDJ40819.1 - 1.5e-08 35.3 5.3 4.5e-07 30.4 5.3 2.5 1 1 0 1 1 1 1 SET domain RHS PF03527.14 CDJ40819.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 RHS protein SR-25 PF10500.9 CDJ40819.1 - 1 8.9 14.7 0.12 11.9 9.2 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein p25-alpha PF05517.12 CDJ40820.1 - 3.2e-30 105.3 0.2 3.6e-30 105.2 0.2 1.0 1 0 0 1 1 1 1 p25-alpha SurA_N PF09312.11 CDJ40820.1 - 0.02 15.0 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 SurA N-terminal domain RHH_4 PF13467.6 CDJ40820.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain Peptidase_S41_N PF11918.8 CDJ40821.1 - 0.0027 17.9 0.1 0.0071 16.6 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of Peptidase_S41 in eukaryotic IRBP OmpH PF03938.14 CDJ40821.1 - 0.07 13.5 16.2 0.29 11.5 4.8 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AAA_23 PF13476.6 CDJ40821.1 - 3.3 8.2 12.8 2.3 8.7 1.5 2.1 2 0 0 2 2 2 0 AAA domain Activator_LAG-3 PF11498.8 CDJ40822.1 - 0.003 16.6 9.2 0.003 16.6 9.2 3.3 2 1 1 3 3 3 1 Transcriptional activator LAG-3 DUF4165 PF13752.6 CDJ40822.1 - 0.043 13.8 0.6 0.079 13.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) FXa_inhibition PF14670.6 CDJ40823.1 - 8.6e-05 22.7 44.1 0.062 13.6 2.5 5.4 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CDJ40823.1 - 8.7e-05 23.0 23.2 0.53 11.0 0.6 5.5 5 0 0 5 5 5 4 Human growth factor-like EGF EGF PF00008.27 CDJ40823.1 - 0.0002 21.6 41.9 0.022 15.1 1.3 5.6 5 0 0 5 5 5 4 EGF-like domain P_C PF06640.11 CDJ40823.1 - 0.00035 20.8 4.7 0.00038 20.7 4.0 1.3 1 1 0 1 1 1 1 P protein C-terminus EGF_CA PF07645.15 CDJ40823.1 - 0.0045 17.2 42.0 0.042 14.1 3.7 5.1 5 0 0 5 5 5 4 Calcium-binding EGF domain cEGF PF12662.7 CDJ40823.1 - 0.073 13.0 1.6 0.073 13.0 1.6 6.4 6 1 0 6 6 6 0 Complement Clr-like EGF-like Form-deh_trans PF09163.11 CDJ40823.1 - 0.47 10.3 0.1 0.47 10.3 0.1 2.2 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane EGF_3 PF12947.7 CDJ40823.1 - 0.87 9.8 46.0 0.27 11.5 3.6 5.8 5 0 0 5 5 5 0 EGF domain Trp_oprn_chp PF09534.10 CDJ40823.1 - 7.2 6.4 11.9 0.79 9.5 5.5 2.1 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Draxin PF15550.6 CDJ40824.1 - 0.0065 16.4 12.5 0.0073 16.2 12.5 1.1 1 0 0 1 1 1 1 Draxin FAM60A PF15396.6 CDJ40824.1 - 0.009 16.0 14.4 0.012 15.6 14.4 1.2 1 0 0 1 1 1 1 Protein Family FAM60A TFIIF_alpha PF05793.12 CDJ40824.1 - 0.057 12.0 17.6 0.073 11.6 17.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF572 PF04502.13 CDJ40824.1 - 0.075 12.6 14.4 0.084 12.5 14.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Rubella_Capsid PF05750.11 CDJ40824.1 - 0.1 12.2 13.0 0.12 11.9 13.0 1.1 1 0 0 1 1 1 0 Rubella capsid protein NST1 PF13945.6 CDJ40824.1 - 0.1 12.7 14.1 0.17 11.9 14.1 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Apt1 PF10351.9 CDJ40824.1 - 0.12 11.2 14.7 0.13 11.1 14.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1168 PF06658.12 CDJ40824.1 - 0.12 12.1 22.5 0.22 11.4 22.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) SWIRM-assoc_2 PF16496.5 CDJ40824.1 - 0.15 10.9 14.5 0.18 10.6 14.5 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal EPL1 PF10513.9 CDJ40824.1 - 0.16 12.3 9.1 0.21 11.9 9.1 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like GREB1 PF15782.5 CDJ40824.1 - 0.18 8.9 13.1 0.19 8.8 13.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 CDJ40824.1 - 0.18 10.1 9.4 0.19 10.0 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 CDJ40824.1 - 0.21 11.5 18.6 0.29 11.0 18.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MCM_bind PF09739.9 CDJ40824.1 - 0.26 9.7 13.8 0.34 9.3 13.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Macoilin PF09726.9 CDJ40824.1 - 0.27 9.7 15.6 0.35 9.4 15.6 1.2 1 0 0 1 1 1 0 Macoilin family SAGA-Tad1 PF12767.7 CDJ40824.1 - 0.32 10.7 10.6 0.38 10.5 10.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit GEMIN8 PF15348.6 CDJ40824.1 - 0.44 10.8 11.1 0.57 10.5 11.1 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF755 PF05501.11 CDJ40824.1 - 0.46 10.8 50.1 1.1 9.5 50.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF755) NARP1 PF12569.8 CDJ40824.1 - 0.48 9.3 16.3 0.55 9.1 16.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Dsh_C PF12316.8 CDJ40824.1 - 0.66 10.3 20.8 0.97 9.8 20.8 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SAPS PF04499.15 CDJ40824.1 - 0.66 8.7 7.5 0.73 8.6 7.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.10 CDJ40824.1 - 0.7 10.2 16.7 0.92 9.8 16.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.13 CDJ40824.1 - 0.74 8.5 15.9 0.84 8.3 15.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.16 CDJ40824.1 - 0.82 9.1 8.7 0.96 8.9 8.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Suf PF05843.14 CDJ40824.1 - 1.1 9.2 9.4 1.3 9.0 9.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4603 PF15376.6 CDJ40824.1 - 1.1 6.6 18.1 1.3 6.3 18.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) SLC12 PF03522.15 CDJ40824.1 - 1.2 8.1 9.5 1.3 7.9 9.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SARAF PF06682.12 CDJ40824.1 - 1.6 8.3 10.5 1.9 8.1 10.5 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2052 PF09747.9 CDJ40824.1 - 1.6 8.8 10.1 2.3 8.3 10.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CDJ40824.1 - 1.7 8.4 14.2 2.1 8.1 14.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CDJ40824.1 - 1.8 7.5 8.7 2.2 7.2 8.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spem1 PF15670.5 CDJ40824.1 - 1.8 8.1 8.6 2.4 7.7 8.6 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 SOBP PF15279.6 CDJ40824.1 - 2 9.0 12.7 2.4 8.7 12.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Raftlin PF15250.6 CDJ40824.1 - 2 7.0 11.3 2.4 6.8 11.3 1.1 1 0 0 1 1 1 0 Raftlin DUF4551 PF15087.6 CDJ40824.1 - 2.5 6.9 13.5 2.6 6.8 13.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PPL5 PF18168.1 CDJ40824.1 - 2.5 7.3 10.1 3.3 6.9 10.1 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 CDJ40824.1 - 2.6 6.7 14.3 3 6.5 14.3 1.1 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 CDJ40824.1 - 2.7 7.7 9.1 3.5 7.4 9.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Rrn6 PF10214.9 CDJ40824.1 - 3 6.2 18.3 3.7 5.9 18.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Neur_chan_memb PF02932.16 CDJ40824.1 - 3.3 7.7 7.9 4 7.4 7.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paramyxo_ncap PF00973.19 CDJ40824.1 - 3.4 6.5 7.7 3.6 6.4 7.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ALMT PF11744.8 CDJ40824.1 - 3.9 6.2 10.3 4.1 6.1 10.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter MAP17 PF15807.5 CDJ40824.1 - 4 7.7 8.5 6.6 7.0 8.5 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Use1 PF09753.9 CDJ40824.1 - 5 6.8 13.1 5.9 6.5 13.1 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Med24_N PF11277.8 CDJ40824.1 - 9.5 4.1 9.0 12 3.8 9.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Peptidase_C12 PF01088.21 CDJ40825.1 - 1.7e-14 54.1 0.0 1.8e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Pox_A31 PF05771.11 CDJ40825.1 - 0.012 15.6 0.1 0.015 15.3 0.1 1.0 1 0 0 1 1 1 0 Poxvirus A31 protein DUF2722 PF10846.8 CDJ40826.1 - 0.27 10.1 15.5 0.06 12.3 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Med3 PF11593.8 CDJ40827.1 - 0.72 9.0 14.5 0.078 12.2 7.5 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Pex14_N PF04695.13 CDJ40827.1 - 1.3 9.6 10.5 0.14 12.8 4.4 2.0 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region OmpH PF03938.14 CDJ40827.1 - 3.8 7.8 13.7 1.3 9.3 8.9 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Activator_LAG-3 PF11498.8 CDJ40827.1 - 4.2 6.2 20.7 0.12 11.3 14.4 1.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ40828.1 - 0.022 14.8 47.4 0.026 14.6 47.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ40828.1 - 0.14 11.1 18.0 0.17 10.8 18.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.6 CDJ40828.1 - 0.19 10.1 3.3 0.22 9.9 3.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAT1 PF09770.9 CDJ40828.1 - 0.33 9.2 32.6 0.4 8.9 32.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CENP-N PF05238.13 CDJ40828.1 - 0.43 9.8 15.7 0.5 9.6 15.7 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Presenilin PF01080.17 CDJ40828.1 - 0.45 9.2 23.3 0.58 8.9 23.3 1.2 1 0 0 1 1 1 0 Presenilin DUF5523 PF17661.1 CDJ40828.1 - 0.54 9.9 14.7 0.68 9.6 14.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) CDC27 PF09507.10 CDJ40828.1 - 0.8 9.0 30.3 1 8.7 30.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SART-1 PF03343.13 CDJ40828.1 - 1.5 7.3 22.2 1.9 6.9 22.2 1.1 1 0 0 1 1 1 0 SART-1 family SOBP PF15279.6 CDJ40828.1 - 3.6 8.1 25.1 6.6 7.2 25.1 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein SR-25 PF10500.9 CDJ40831.1 - 0.0015 18.2 1.1 0.0015 18.2 1.1 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein PAD_M PF08527.10 CDJ40831.1 - 0.087 12.5 1.6 4.1 7.0 0.1 2.2 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain MCU PF04678.13 CDJ40831.1 - 0.22 11.6 6.1 0.22 11.6 1.1 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter MAS20 PF02064.15 CDJ40831.1 - 0.25 11.4 10.1 3.6 7.7 3.4 2.6 2 0 0 2 2 2 0 MAS20 protein import receptor Synuclein PF01387.17 CDJ40831.1 - 1.6 8.9 6.9 1.9 8.7 1.5 2.8 2 1 1 3 3 3 0 Synuclein Med15 PF09606.10 CDJ40831.1 - 9.5 4.8 35.2 0.064 11.9 3.5 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Androgen_recep PF02166.16 CDJ40832.1 - 7 5.4 10.2 8.2 5.1 10.2 1.1 1 0 0 1 1 1 0 Androgen receptor BT1 PF03092.16 CDJ40833.1 - 9.7e-10 37.3 0.0 1.1e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.16 CDJ40833.1 - 0.0059 15.6 0.2 0.006 15.6 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CTD_bind PF04818.13 CDJ40834.1 - 5.8e-15 55.9 0.1 1.7e-14 54.4 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Surp PF01805.20 CDJ40834.1 - 7.1e-07 29.1 0.0 2.2e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Surp module Mito_fiss_reg PF05308.11 CDJ40834.1 - 0.015 15.4 3.8 0.015 15.4 3.8 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF2076 PF09849.9 CDJ40834.1 - 0.016 15.2 7.4 0.031 14.3 7.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SUIM_assoc PF16619.5 CDJ40834.1 - 0.023 14.8 5.0 0.023 14.8 5.0 3.5 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ40834.1 - 0.044 13.4 3.2 0.068 12.8 3.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ40834.1 - 0.082 12.5 9.3 0.16 11.6 9.3 1.4 1 0 0 1 1 1 0 Spt20 family IMUP PF15761.5 CDJ40834.1 - 0.11 13.2 1.6 0.23 12.2 1.6 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein VIR_N PF15912.5 CDJ40834.1 - 0.11 12.1 4.5 0.22 11.1 4.5 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal PPI_Ypi1 PF07491.11 CDJ40834.1 - 0.15 11.9 6.3 0.18 11.7 0.0 3.1 3 0 0 3 3 3 0 Protein phosphatase inhibitor Ndc1_Nup PF09531.10 CDJ40834.1 - 0.55 8.9 5.5 0.66 8.6 5.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3292 PF11696.8 CDJ40834.1 - 0.68 8.2 4.5 0.93 7.8 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) FAD-SLDH PF12318.8 CDJ40834.1 - 2.4 8.2 9.1 0.14 12.2 0.7 2.8 1 1 2 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase Ribosomal_60s PF00428.19 CDJ40835.1 - 0.035 14.7 7.8 0.068 13.8 7.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3138 PF11336.8 CDJ40835.1 - 0.11 11.1 5.6 0.13 10.9 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ATPase PF06745.13 CDJ40836.1 - 0.011 15.0 0.9 0.02 14.2 0.9 1.4 1 0 0 1 1 1 0 KaiC TFIIA PF03153.13 CDJ40836.1 - 0.31 11.0 50.9 0.55 10.2 50.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Z1 PF10593.9 CDJ40836.1 - 0.34 10.4 7.9 0.69 9.4 7.9 1.6 1 0 0 1 1 1 0 Z1 domain Tet_JBP PF12851.7 CDJ40836.1 - 1.2 8.4 7.7 1.6 8.0 7.7 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily SOBP PF15279.6 CDJ40836.1 - 6.4 7.3 17.7 9.4 6.7 17.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4746 PF15928.5 CDJ40836.1 - 7.1 6.0 7.0 9.4 5.6 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SPX PF03105.19 CDJ40837.1 - 0.29 11.0 12.8 0.39 10.6 12.8 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ40837.1 - 1.3 7.8 12.0 1.8 7.3 12.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1645 PF07816.11 CDJ40837.1 - 1.5 9.4 20.8 1.8 9.1 12.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DUF2722 PF10846.8 CDJ40839.1 - 0.00035 19.7 5.3 0.00035 19.7 5.3 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ40839.1 - 0.001 20.0 9.3 0.0057 17.6 0.1 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4834) Eisosome1 PF12757.7 CDJ40839.1 - 0.015 15.6 8.5 0.015 15.6 8.5 4.6 2 1 1 3 3 3 0 Eisosome protein 1 RskA PF10099.9 CDJ40839.1 - 0.079 13.2 0.3 0.079 13.2 0.3 3.6 1 1 2 3 3 3 0 Anti-sigma-K factor rskA ATG22 PF11700.8 CDJ40839.1 - 0.12 11.0 1.7 0.19 10.4 0.9 1.7 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Peptidase_S49_N PF08496.10 CDJ40839.1 - 2 8.5 8.4 0.38 10.8 0.2 2.7 3 0 0 3 3 3 0 Peptidase family S49 N-terminal eIF-3_zeta PF05091.12 CDJ40839.1 - 5.4 5.9 14.2 0.87 8.5 5.7 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ40839.1 - 5.9 4.7 10.3 0.048 11.6 0.6 2.2 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Spore_III_AF PF09581.10 CDJ40839.1 - 6.1 6.8 9.8 0.07 13.2 0.5 2.4 2 1 1 3 3 3 0 Stage III sporulation protein AF (Spore_III_AF) DUF4820 PF16091.5 CDJ40839.1 - 7.2 5.9 14.8 0.3 10.4 3.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4820) ATP_bind_1 PF03029.17 CDJ40840.1 - 1.4e-73 247.7 0.0 1.9e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CDJ40840.1 - 0.0017 18.2 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop Mg_chelatase PF01078.21 CDJ40840.1 - 0.019 14.4 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI GTP_EFTU PF00009.27 CDJ40840.1 - 0.051 13.1 0.0 0.085 12.4 0.0 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 CDJ40840.1 - 0.053 14.1 0.4 0.23 12.0 0.0 2.3 1 1 0 2 2 2 0 AAA domain CbiA PF01656.23 CDJ40840.1 - 0.095 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 CDJ40840.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CDJ40840.1 - 0.13 12.5 0.0 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 CDJ40840.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 CDJ40840.1 - 0.18 11.9 0.0 9.9 6.3 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase DctQ PF04290.12 CDJ40842.1 - 0.008 16.1 0.1 0.011 15.6 0.1 1.1 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component DUF5527 PF17665.1 CDJ40842.1 - 0.062 12.8 0.1 0.09 12.3 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) DUF5408 PF17402.2 CDJ40842.1 - 0.34 10.8 0.9 0.55 10.2 0.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5408) LpxI_N PF17930.1 CDJ40843.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 LpxI N-terminal domain Fer2 PF00111.27 CDJ40844.1 - 4.1e-19 68.3 1.4 4.1e-19 68.3 1.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain CaKB PF03185.15 CDJ40844.1 - 0.0017 18.0 12.2 0.13 11.9 6.3 2.1 2 0 0 2 2 2 2 Calcium-activated potassium channel, beta subunit Fer2_4 PF13510.6 CDJ40844.1 - 0.0093 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Serinc PF03348.15 CDJ40844.1 - 0.11 11.4 5.1 0.18 10.7 5.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) OATP PF03137.20 CDJ40844.1 - 0.15 10.3 7.2 0.29 9.4 7.2 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SID-1_RNA_chan PF13965.6 CDJ40844.1 - 0.16 10.4 1.6 0.13 10.6 1.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FAM176 PF14851.6 CDJ40844.1 - 0.29 10.8 6.0 0.63 9.7 6.0 1.5 1 0 0 1 1 1 0 FAM176 family Peptidase_U57 PF05582.12 CDJ40844.1 - 0.62 9.3 7.8 1.1 8.5 7.8 1.4 1 0 0 1 1 1 0 YabG peptidase U57 Pal1 PF08316.11 CDJ40844.1 - 1.3 9.7 12.3 4.1 8.2 0.2 2.2 2 0 0 2 2 2 0 Pal1 cell morphology protein Usp PF00582.26 CDJ40844.1 - 1.7 9.2 6.8 3.8 8.0 0.2 2.3 2 0 0 2 2 2 0 Universal stress protein family Ureide_permease PF07168.11 CDJ40844.1 - 2.6 6.7 5.3 4.6 5.9 5.3 1.3 1 0 0 1 1 1 0 Ureide permease CPSF100_C PF13299.6 CDJ40844.1 - 2.8 8.1 15.0 0.089 13.0 7.6 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Peroxin-13_N PF04088.13 CDJ40844.1 - 3.5 7.9 11.5 0.34 11.2 6.1 2.0 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Connexin PF00029.19 CDJ40844.1 - 4 7.1 13.0 0.92 9.2 9.8 1.5 2 0 0 2 2 2 0 Connexin LMBR1 PF04791.16 CDJ40844.1 - 4.3 6.1 4.8 3.9 6.3 4.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PIP5K PF01504.18 CDJ40844.1 - 4.7 6.4 12.5 0.53 9.5 7.9 1.7 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF2232 PF09991.9 CDJ40844.1 - 6.2 5.9 6.0 12 4.9 6.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) MDM31_MDM32 PF08118.11 CDJ40844.1 - 6.2 5.4 9.2 9.8 4.7 9.2 1.3 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Baculo_PP31 PF05311.11 CDJ40844.1 - 6.4 6.2 15.2 0.83 9.1 11.1 1.5 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) HCO3_cotransp PF00955.21 CDJ40844.1 - 6.6 5.4 6.3 9.2 4.9 6.3 1.2 1 0 0 1 1 1 0 HCO3- transporter family Folate_carrier PF01770.18 CDJ40844.1 - 8.2 5.0 8.7 12 4.5 8.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier PI3_PI4_kinase PF00454.27 CDJ40845.1 - 4e-10 39.9 8.3 2.4e-07 30.9 0.0 3.1 3 0 0 3 3 3 2 Phosphatidylinositol 3- and 4-kinase Spt20 PF12090.8 CDJ40845.1 - 2e-05 24.4 6.0 2e-05 24.4 6.0 9.8 10 0 0 10 10 10 4 Spt20 family RskA PF10099.9 CDJ40845.1 - 0.16 12.2 0.0 0.16 12.2 0.0 13.3 9 3 4 13 13 13 0 Anti-sigma-K factor rskA Gln_deamidase_2 PF18626.1 CDJ40846.1 - 0.37 11.1 5.3 0.73 10.1 5.3 1.6 1 1 0 1 1 1 0 Glutaminase SPX PF03105.19 CDJ40847.1 - 0.86 9.5 0.0 0.86 9.5 0.0 6.9 4 3 1 6 6 6 0 SPX domain U1snRNP70_N PF12220.8 CDJ40848.1 - 0.001 19.6 9.9 0.0088 16.7 9.9 2.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4638 PF15472.6 CDJ40848.1 - 2.8 7.6 10.4 0.22 11.2 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) SCAI PF12070.8 CDJ40848.1 - 4.3 6.1 7.3 6.5 5.5 7.3 1.2 1 0 0 1 1 1 0 Protein SCAI Kazal_2 PF07648.15 CDJ40849.1 - 2.8e-22 78.6 10.8 3.2e-11 43.2 3.1 3.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CDJ40849.1 - 4.9e-19 68.1 9.4 4.3e-10 39.4 4.6 2.8 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain MbeD_MobD PF04899.12 CDJ40850.1 - 2.1 8.5 15.4 0.29 11.3 1.2 2.6 2 0 0 2 2 2 0 MbeD/MobD like Synaptobrevin PF00957.21 CDJ40851.1 - 7.3e-25 86.6 0.3 1.7e-24 85.4 0.3 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CDJ40851.1 - 4e-19 68.4 0.1 9.9e-19 67.2 0.1 1.7 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 CDJ40851.1 - 0.061 13.0 0.1 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region MCU PF04678.13 CDJ40851.1 - 0.18 11.9 0.5 0.48 10.5 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DNA_pol_A PF00476.20 CDJ40852.1 - 8.9e-62 209.3 0.0 6.9e-57 193.2 0.0 2.1 2 0 0 2 2 2 2 DNA polymerase family A Metaviral_G PF09595.10 CDJ40852.1 - 3 7.9 13.5 0.34 11.0 1.7 2.3 1 1 1 2 2 2 0 Metaviral_G glycoprotein Raco_middle PF17651.1 CDJ40853.1 - 2 8.1 6.1 3.2 7.4 0.9 3.3 3 1 0 3 3 3 0 RACo middle region Laminin_G_3 PF13385.6 CDJ40854.1 - 9.3e-15 55.1 0.0 1.5e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 CDJ40854.1 - 2.9e-05 24.6 0.1 0.00012 22.6 0.0 2.1 2 1 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.23 CDJ40854.1 - 0.00011 22.5 0.0 0.00032 20.9 0.0 1.8 2 1 0 2 2 2 1 Laminin G domain Sin3_corepress PF08295.12 CDJ40855.1 - 1.1e-21 76.7 0.0 2.5e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor DUF4404 PF14357.6 CDJ40856.1 - 0.043 14.5 0.0 0.084 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DEAD PF00270.29 CDJ40857.1 - 3.2e-14 53.1 2.2 3.4e-13 49.7 2.2 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CDJ40857.1 - 2.3e-10 41.1 0.5 2.3e-10 41.1 0.5 4.1 4 0 0 4 4 4 1 RecQ zinc-binding ResIII PF04851.15 CDJ40857.1 - 7.4e-09 35.8 0.3 7.4e-09 35.8 0.3 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ40857.1 - 0.00053 20.3 0.6 0.88 9.9 0.0 3.2 3 1 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ40857.1 - 0.85 9.9 6.7 0.22 11.8 2.4 2.3 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CDJ40857.1 - 1.9 8.2 14.2 0.14 11.9 4.2 3.4 4 0 0 4 4 4 0 AAA domain PA26 PF04636.13 CDJ40857.1 - 3.2 6.6 8.6 0.86 8.5 4.0 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Band_3_cyto PF07565.13 CDJ40857.1 - 5.1 6.8 12.7 0.021 14.7 2.1 2.3 3 0 0 3 3 3 0 Band 3 cytoplasmic domain 2-oxoacid_dh PF00198.23 CDJ40859.1 - 8.3e-67 225.0 0.0 1.1e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CDJ40859.1 - 3.7e-19 68.3 0.7 6.1e-19 67.6 0.7 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CDJ40859.1 - 3.3e-16 59.3 1.1 1.7e-15 57.0 0.3 2.4 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CDJ40859.1 - 3.8e-08 33.0 0.0 1.2e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_D23 PF16576.5 CDJ40859.1 - 1.5e-06 27.6 0.0 3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion PTS_EIIA_1 PF00358.20 CDJ40859.1 - 0.014 15.2 0.0 0.065 13.0 0.0 1.9 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 GCV_H PF01597.19 CDJ40859.1 - 0.041 13.8 0.1 0.083 12.8 0.1 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein Ndc1_Nup PF09531.10 CDJ40859.1 - 1.2 7.7 3.6 1.7 7.2 3.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAP PF07174.11 CDJ40861.1 - 0.09 12.2 19.0 0.22 10.9 19.0 1.6 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) COX4_pro PF03626.14 CDJ40861.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic Cytochrome C oxidase subunit IV DUF1631 PF07793.11 CDJ40861.1 - 0.81 8.0 5.2 1.1 7.6 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Dfp1_Him1_M PF08630.10 CDJ40862.1 - 1.6 9.0 6.8 1 9.6 1.5 3.1 2 0 0 2 2 2 0 Dfp1/Him1, central region Med4 PF10018.9 CDJ40862.1 - 2.4 7.8 13.8 0.15 11.7 5.7 3.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 PIP5K PF01504.18 CDJ40862.1 - 4.1 6.5 4.8 11 5.1 1.6 2.7 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Sec23_trunk PF04811.15 CDJ40863.1 - 2.9e-53 180.9 0.0 2.9e-53 180.9 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CDJ40863.1 - 1.6e-29 102.5 0.0 1.6e-29 102.5 0.0 2.2 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CDJ40863.1 - 4e-23 81.2 0.3 4e-23 81.2 0.3 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CDJ40863.1 - 1e-12 47.9 3.8 2.1e-12 46.9 3.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CDJ40863.1 - 7.9e-11 41.7 0.0 7.9e-11 41.7 0.0 2.9 2 2 0 2 2 2 1 Gelsolin repeat RNase_E_G PF10150.9 CDJ40863.1 - 0.038 13.4 5.5 0.06 12.8 5.5 1.2 1 0 0 1 1 1 0 Ribonuclease E/G family TFIIA PF03153.13 CDJ40863.1 - 0.043 13.8 24.0 0.067 13.2 24.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM222A PF15258.6 CDJ40863.1 - 0.66 9.0 18.7 1.1 8.3 18.7 1.2 1 0 0 1 1 1 0 Protein family of FAM222A Tfb5 PF06331.12 CDJ40864.1 - 4.4e-21 74.6 0.3 5.6e-21 74.3 0.3 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Rad51 PF08423.11 CDJ40865.1 - 4.8e-50 170.2 0.0 5.4e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Rad51 Mx_ML PF17536.2 CDJ40865.1 - 0.079 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Matrix and Matrix long proteins N-terminal SAPS PF04499.15 CDJ40866.1 - 0.078 11.7 2.3 0.12 11.1 2.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SelK_SelG PF10961.8 CDJ40866.1 - 0.23 12.1 4.5 0.49 11.0 2.2 2.4 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Presenilin PF01080.17 CDJ40866.1 - 2.2 6.9 14.9 0.3 9.8 10.0 1.8 2 0 0 2 2 2 0 Presenilin DivIC PF04977.15 CDJ40867.1 - 0.04 13.7 4.1 0.04 13.7 4.1 2.2 2 0 0 2 2 2 0 Septum formation initiator BCCT PF02028.17 CDJ40867.1 - 0.09 11.2 0.1 0.11 11.0 0.1 1.0 1 0 0 1 1 1 0 BCCT, betaine/carnitine/choline family transporter DUF913 PF06025.12 CDJ40867.1 - 0.099 11.6 3.7 0.13 11.3 3.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ANAPC_CDC26 PF10471.9 CDJ40867.1 - 0.1 13.4 26.1 0.87 10.5 10.8 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 RskA PF10099.9 CDJ40867.1 - 0.16 12.3 16.2 0.2 12.0 16.2 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ40867.1 - 0.35 9.6 9.8 0.44 9.2 9.8 1.1 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 CDJ40867.1 - 0.39 9.6 27.8 0.27 10.2 11.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DDDD PF10161.9 CDJ40867.1 - 0.4 10.5 2.7 0.52 10.1 0.1 1.9 1 1 1 2 2 2 0 Putative mitochondrial precursor protein SARAF PF06682.12 CDJ40867.1 - 0.79 9.3 9.1 0.99 9.0 9.1 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Hid1 PF12722.7 CDJ40867.1 - 0.92 7.6 8.1 1 7.4 8.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lin-8 PF03353.15 CDJ40867.1 - 1.2 8.6 12.1 1.6 8.2 12.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mak10 PF04112.13 CDJ40867.1 - 2.4 7.6 6.1 1.4 8.4 0.1 2.0 2 0 0 2 2 2 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Conotoxin PF02950.17 CDJ40867.1 - 6.1 7.9 9.9 23 6.1 0.4 2.2 2 0 0 2 2 2 0 Conotoxin Protamine_P2 PF00841.19 CDJ40867.1 - 6.7 7.3 17.1 9 6.9 5.4 2.1 2 0 0 2 2 2 0 Sperm histone P2 TetR_C_8 PF14278.6 CDJ40869.1 - 0.0099 16.0 3.3 0.18 11.9 0.2 2.2 2 0 0 2 2 2 1 Transcriptional regulator C-terminal region JHBP PF06585.11 CDJ40869.1 - 0.023 13.9 2.4 0.12 11.5 0.2 2.2 1 1 1 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) LepB_N PF18640.1 CDJ40869.1 - 0.05 13.2 11.1 58 3.2 11.1 2.6 1 1 0 1 1 1 0 LepB N-terminal domain Skp1_POZ PF03931.15 CDJ40869.1 - 0.12 12.6 6.0 2.2 8.5 2.4 2.9 1 1 1 2 2 2 0 Skp1 family, tetramerisation domain B12-binding_2 PF02607.17 CDJ40869.1 - 0.17 12.4 10.6 5.3e+02 1.2 10.6 3.2 1 1 0 1 1 1 0 B12 binding domain OSCP PF00213.18 CDJ40869.1 - 0.2 11.8 10.5 0.55 10.3 10.5 1.6 1 1 0 1 1 1 0 ATP synthase delta (OSCP) subunit DUF29 PF01724.16 CDJ40869.1 - 0.28 11.4 6.6 3.8 7.8 1.0 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF29 MCM_N PF14551.6 CDJ40869.1 - 0.56 10.8 12.7 70 4.1 11.9 2.8 1 1 0 1 1 1 0 MCM N-terminal domain Trigger_N PF05697.13 CDJ40869.1 - 0.76 10.1 7.1 5 7.4 1.2 2.8 1 1 1 2 2 2 0 Bacterial trigger factor protein (TF) SATase_N PF06426.14 CDJ40869.1 - 0.78 10.1 8.7 14 6.2 8.7 2.2 1 1 0 1 1 1 0 Serine acetyltransferase, N-terminal DUF913 PF06025.12 CDJ40869.1 - 1.3 8.0 7.6 1.5 7.7 7.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) zf-CRD PF17979.1 CDJ40869.1 - 1.4 9.0 10.0 1.7 8.7 3.8 2.1 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions Het-C PF07217.11 CDJ40869.1 - 1.7 7.1 10.1 2.1 6.8 10.1 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C PDDEXK_1 PF12705.7 CDJ40869.1 - 1.9 8.3 7.2 8.3 6.2 7.2 1.9 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Knl1_RWD_C PF18210.1 CDJ40869.1 - 2.1 8.9 14.7 2.6 8.6 4.7 2.5 1 1 1 2 2 2 0 Knl1 RWD C-terminal domain AAA_32 PF13654.6 CDJ40869.1 - 2.1 7.0 11.5 4.3 6.0 11.5 1.5 1 1 0 1 1 1 0 AAA domain Dynamin_M PF01031.20 CDJ40869.1 - 2.1 7.5 15.4 2.7 7.1 4.1 2.1 1 1 1 2 2 2 0 Dynamin central region RecG_N PF17190.4 CDJ40869.1 - 2.4 9.0 7.7 6.3 7.6 1.7 2.5 1 1 1 2 2 2 0 RecG N-terminal helical domain SesA PF17107.5 CDJ40869.1 - 2.7 8.2 17.7 3.5 7.8 7.5 2.6 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF2935 PF11155.8 CDJ40869.1 - 3.5 8.0 12.6 62 3.9 12.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) CsiD PF08943.10 CDJ40869.1 - 5.9 5.9 12.0 25 3.9 12.0 1.8 1 1 0 1 1 1 0 CsiD WASH_WAHD PF11945.8 CDJ40869.1 - 6.4 6.2 17.6 1.9 7.9 6.6 2.2 1 1 1 2 2 2 0 WAHD domain of WASH complex PXB PF12828.7 CDJ40869.1 - 7 6.6 11.3 1.8e+02 2.1 11.2 2.4 1 1 0 1 1 1 0 PX-associated DUF3461 PF11944.8 CDJ40869.1 - 7.1 6.8 11.7 1.9 8.6 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) IFT57 PF10498.9 CDJ40869.1 - 7.7 5.4 15.9 9.1 5.1 15.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 MutS_III PF05192.18 CDJ40869.1 - 9.3 6.4 9.1 18 5.5 9.1 1.5 1 1 0 1 1 1 0 MutS domain III MAT1 PF06391.13 CDJ40870.1 - 2.3e-08 34.1 16.6 6.2e-08 32.7 16.6 1.6 1 1 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.6 CDJ40870.1 - 3.3e-05 23.7 11.2 6.5e-05 22.8 11.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ40870.1 - 0.014 15.3 8.2 0.04 13.8 8.2 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ40870.1 - 0.032 14.6 12.2 0.43 10.9 13.4 2.1 1 1 1 2 2 2 0 Ring finger domain Lin-8 PF03353.15 CDJ40870.1 - 0.04 13.5 7.5 0.051 13.1 7.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-RING_UBOX PF13445.6 CDJ40870.1 - 0.05 13.6 9.5 0.41 10.7 6.0 2.8 2 0 0 2 2 2 0 RING-type zinc-finger Rad50_zn_hook PF04423.14 CDJ40870.1 - 0.085 12.7 0.0 0.085 12.7 0.0 3.1 4 0 0 4 4 4 0 Rad50 zinc hook motif Histidinol_dh PF00815.20 CDJ40870.1 - 0.09 11.8 1.5 0.12 11.3 1.5 1.1 1 0 0 1 1 1 0 Histidinol dehydrogenase PAP1 PF08601.10 CDJ40870.1 - 0.1 12.3 10.1 0.13 12.0 10.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Prok-RING_4 PF14447.6 CDJ40870.1 - 0.23 11.4 10.9 1 9.3 10.9 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF572 PF04502.13 CDJ40870.1 - 0.62 9.6 10.0 0.84 9.2 10.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Presenilin PF01080.17 CDJ40870.1 - 1.4 7.6 11.0 1.9 7.2 11.0 1.1 1 0 0 1 1 1 0 Presenilin Tweety PF04906.13 CDJ40870.1 - 1.5 7.4 3.5 1.9 7.0 1.0 1.9 1 1 1 2 2 2 0 Tweety zf-C3HC4_5 PF17121.5 CDJ40870.1 - 1.5 8.7 12.2 0.26 11.2 5.8 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ40870.1 - 2.5 8.0 11.5 36 4.3 0.0 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3740 PF12548.8 CDJ40870.1 - 4.6 7.7 13.2 0.086 13.3 3.7 2.2 1 1 1 2 2 2 0 Sulfatase protein zf-4CXXC_R1 PF10497.9 CDJ40870.1 - 6.1 7.1 11.9 2.9 8.2 8.1 2.3 2 1 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 E7 PF00527.18 CDJ40873.1 - 0.025 14.8 0.1 0.037 14.2 0.1 1.2 1 0 0 1 1 1 0 E7 protein, Early protein Tmemb_9 PF05434.11 CDJ40873.1 - 0.038 13.9 0.2 0.055 13.4 0.1 1.4 1 1 0 1 1 1 0 TMEM9 Amnionless PF14828.6 CDJ40873.1 - 0.077 11.8 0.1 0.079 11.8 0.1 1.1 1 0 0 1 1 1 0 Amnionless Fungus-induced PF10917.8 CDJ40874.1 - 0.15 12.4 0.0 0.19 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungus-induced protein SPX PF03105.19 CDJ40875.1 - 0.013 15.5 6.1 0.017 15.1 6.1 1.1 1 0 0 1 1 1 0 SPX domain EII-Sor PF03609.14 CDJ40875.1 - 0.052 12.9 0.3 0.052 12.9 0.3 1.6 2 0 0 2 2 2 0 PTS system sorbose-specific iic component DUF572 PF04502.13 CDJ40875.1 - 0.22 11.1 4.1 0.31 10.6 4.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) RIFIN PF02009.16 CDJ40875.1 - 0.37 10.7 7.8 0.59 10.0 7.8 1.3 1 0 0 1 1 1 0 Rifin Mlf1IP PF10248.9 CDJ40875.1 - 0.47 10.4 5.1 0.7 9.9 5.1 1.2 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Apt1 PF10351.9 CDJ40875.1 - 0.83 8.4 9.2 1.1 8.0 9.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 CDJ40875.1 - 0.92 9.5 16.7 1.5 8.8 16.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF1635 PF07795.11 CDJ40875.1 - 1.9 8.3 6.3 3.7 7.4 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) RAP1 PF07218.11 CDJ40875.1 - 2.4 6.3 19.6 3 6.0 19.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RSRP PF17069.5 CDJ40875.1 - 4.8 6.7 27.7 8.1 5.9 27.7 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Pox_A12 PF04651.13 CDJ40875.1 - 5.4 7.0 12.4 9.4 6.3 12.4 1.4 1 0 0 1 1 1 0 Poxvirus A12 protein PMSR PF01625.21 CDJ40876.1 - 3.9e-52 176.5 0.0 4.6e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF4390 PF14334.6 CDJ40876.1 - 0.076 12.4 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) Nucleoporin_FG2 PF15967.5 CDJ40876.1 - 4.7 5.6 10.4 5.7 5.4 10.4 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Sporozoite_P67 PF05642.11 CDJ40877.1 - 0.041 12.0 0.2 0.088 10.9 0.2 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3464 PF11947.8 CDJ40877.1 - 1.3 8.8 12.4 6.9 6.4 0.0 3.2 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 CCDC53 PF10152.9 CDJ40877.1 - 5.8 7.3 22.9 5.4 7.4 1.6 3.6 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Macoilin PF09726.9 CDJ40878.1 - 0.05 12.2 17.9 0.054 12.1 17.9 1.0 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CDJ40878.1 - 0.12 12.4 39.9 0.13 12.3 39.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 CDJ40878.1 - 0.15 12.3 20.9 0.18 12.1 20.9 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DehI PF10778.9 CDJ40878.1 - 0.17 12.1 10.9 0.17 12.0 10.4 1.3 1 1 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI DUF1387 PF07139.11 CDJ40878.1 - 0.54 9.9 15.2 0.61 9.8 15.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) PAT1 PF09770.9 CDJ40878.1 - 0.64 8.2 23.9 0.68 8.1 23.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 CDJ40878.1 - 0.72 9.4 16.5 0.78 9.2 16.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RIFIN PF02009.16 CDJ40878.1 - 0.99 9.2 13.0 1.1 9.0 13.0 1.0 1 0 0 1 1 1 0 Rifin Plasmodium_Vir PF05795.11 CDJ40878.1 - 1.7 8.0 8.9 1.8 7.9 8.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein EMC3_TMCO1 PF01956.16 CDJ40878.1 - 5.1 6.8 7.0 6.1 6.5 7.0 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like SLC12 PF03522.15 CDJ40878.1 - 8 5.4 12.9 9.1 5.2 12.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF501 PF04417.12 CDJ40879.1 - 1e-16 61.0 1.7 1.1e-09 38.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF501) Bacteriocin_IIc PF10439.9 CDJ40879.1 - 3.2 7.9 11.6 0.085 13.0 3.2 2.1 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide S1 PF00575.23 CDJ40880.1 - 1.3e-27 95.9 1.2 2.1e-14 53.6 0.1 2.5 2 0 0 2 2 2 2 S1 RNA binding domain zf-CCHC_3 PF13917.6 CDJ40880.1 - 3.8e-08 33.2 1.2 9.6e-08 31.9 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Dehydrin PF00257.19 CDJ40880.1 - 1.7e-06 28.7 7.1 2.9e-06 28.0 7.1 1.4 1 0 0 1 1 1 1 Dehydrin S1_2 PF13509.6 CDJ40880.1 - 0.0042 17.1 0.0 1.6 8.9 0.0 2.9 2 1 0 2 2 2 1 S1 domain CSD PF00313.22 CDJ40880.1 - 0.012 15.4 0.1 2.6 8.0 0.0 2.6 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain zf-CCHC PF00098.23 CDJ40880.1 - 0.019 15.0 5.4 0.019 15.0 5.4 1.9 2 0 0 2 2 2 0 Zinc knuckle RskA PF10099.9 CDJ40880.1 - 0.16 12.3 5.4 0.32 11.3 5.4 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Nucleo_P87 PF07267.11 CDJ40880.1 - 0.27 10.1 5.0 0.34 9.7 5.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DDHD PF02862.17 CDJ40880.1 - 0.88 9.7 6.1 1.6 8.9 6.1 1.5 1 0 0 1 1 1 0 DDHD domain SRP-alpha_N PF04086.13 CDJ40880.1 - 0.92 9.4 17.1 1.3 8.9 17.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF1980 PF09323.10 CDJ40880.1 - 1.1 9.1 3.8 1.7 8.5 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Presenilin PF01080.17 CDJ40880.1 - 1.6 7.4 9.3 1.9 7.1 9.3 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ40880.1 - 1.7 8.2 13.4 2.3 7.8 13.4 1.2 1 0 0 1 1 1 0 Spt20 family RR_TM4-6 PF06459.12 CDJ40880.1 - 1.7 8.4 10.2 2.5 7.9 10.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med19 PF10278.9 CDJ40880.1 - 2.7 7.9 19.1 4 7.3 19.1 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Pap_E4 PF02711.14 CDJ40880.1 - 5 8.2 12.2 13 6.8 12.2 1.7 1 0 0 1 1 1 0 E4 protein RNA_pol_Rpc4 PF05132.14 CDJ40880.1 - 9 6.7 16.4 21 5.5 16.4 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Thioredoxin PF00085.20 CDJ40881.1 - 1.4e-55 185.6 0.0 2.4e-31 107.8 0.2 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CDJ40881.1 - 3.2e-20 72.8 0.0 6.4e-09 36.0 0.0 3.7 2 2 1 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 CDJ40881.1 - 1.2e-11 44.5 0.2 1.9e-06 27.5 0.0 2.5 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CDJ40881.1 - 4e-11 43.3 0.7 3.8e-05 24.1 0.1 3.3 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDJ40881.1 - 1.6e-09 37.8 5.9 0.00035 20.7 0.1 4.2 3 1 1 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.17 CDJ40881.1 - 1.4e-08 34.2 0.0 4.3e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Calsequestrin AhpC-TSA PF00578.21 CDJ40881.1 - 5.9e-08 32.7 0.1 5.5e-05 23.1 0.1 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 CDJ40881.1 - 6.7e-08 32.7 0.0 0.0024 18.2 0.0 3.3 3 1 1 4 4 4 2 Thioredoxin-like TraF PF13728.6 CDJ40881.1 - 7.2e-08 32.5 0.0 0.0077 16.1 0.0 2.7 3 0 0 3 3 3 2 F plasmid transfer operon protein Redoxin PF08534.10 CDJ40881.1 - 5.8e-06 26.1 0.8 0.0017 18.1 0.1 3.1 2 1 1 3 3 3 1 Redoxin ERp29_N PF07912.13 CDJ40881.1 - 0.00031 20.9 0.0 1.7 8.8 0.0 2.9 3 0 0 3 3 3 2 ERp29, N-terminal domain Glutaredoxin PF00462.24 CDJ40881.1 - 0.00082 19.6 1.4 3.8 7.8 0.0 4.0 3 1 0 3 3 3 2 Glutaredoxin Thioredoxin_9 PF14595.6 CDJ40881.1 - 0.0098 15.7 0.0 4 7.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin FAM60A PF15396.6 CDJ40882.1 - 0.00096 19.2 13.1 0.00096 19.2 13.1 4.7 2 1 1 3 3 3 1 Protein Family FAM60A IMUP PF15761.5 CDJ40882.1 - 0.019 15.7 3.7 0.019 15.7 3.7 6.6 5 1 1 7 7 7 0 Immortalisation up-regulated protein Glu_cyclase_2 PF05096.12 CDJ40883.1 - 5.4e-10 39.1 0.0 2.5e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Glutamine cyclotransferase TFIIA PF03153.13 CDJ40883.1 - 0.56 10.2 24.8 1.1 9.2 24.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Chorion_2 PF03964.15 CDJ40883.1 - 6.3 7.7 16.4 8.8 7.2 0.4 3.5 3 0 0 3 3 3 0 Chorion family 2 CKS PF01111.19 CDJ40884.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit SNARE PF05739.19 CDJ40886.1 - 0.00099 19.1 2.4 0.00099 19.1 2.4 2.3 2 0 0 2 2 2 1 SNARE domain Remorin_C PF03763.13 CDJ40886.1 - 0.0064 16.4 2.0 0.0064 16.4 2.0 2.2 2 0 0 2 2 2 1 Remorin, C-terminal region SOAR PF16533.5 CDJ40886.1 - 0.022 14.7 6.8 0.2 11.7 0.9 2.7 3 0 0 3 3 3 0 STIM1 Orai1-activating region Laminin_II PF06009.12 CDJ40886.1 - 0.3 11.1 10.6 0.49 10.4 0.3 2.5 2 1 0 2 2 2 0 Laminin Domain II Syntaxin_2 PF14523.6 CDJ40886.1 - 0.59 10.5 17.9 0.078 13.4 9.4 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Hom_end_hint PF05203.16 CDJ40886.1 - 0.93 9.4 3.8 0.59 10.1 2.1 1.5 1 1 0 1 1 1 0 Hom_end-associated Hint IZUMO PF15005.6 CDJ40886.1 - 1.8 9.1 5.6 16 6.0 0.1 2.7 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Fib_alpha PF08702.10 CDJ40886.1 - 2.4 8.3 9.8 2.9 8.1 3.5 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CorA PF01544.18 CDJ40886.1 - 2.4 7.4 11.6 0.16 11.3 5.7 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Rx_N PF18052.1 CDJ40886.1 - 5.2 7.4 9.5 27 5.1 0.5 3.5 2 1 1 3 3 3 0 Rx N-terminal domain HisKA_3 PF07730.13 CDJ40886.1 - 5.4 7.6 12.4 1.3 9.6 0.1 3.8 4 2 0 4 4 4 0 Histidine kinase T3SS_needle_E PF08988.10 CDJ40886.1 - 6.3 7.0 8.7 13 6.0 3.7 3.2 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle EMP24_GP25L PF01105.24 CDJ40887.1 - 2.4e-20 73.3 0.0 3.1e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TrmO_C PF18389.1 CDJ40888.1 - 0.17 12.0 0.5 0.17 12.0 0.5 2.0 2 0 0 2 2 2 0 TrmO C-terminal domain Med3 PF11593.8 CDJ40888.1 - 7.7 5.6 17.2 3.5 6.7 1.8 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal RNA_pol_Rpb4 PF03874.16 CDJ40889.1 - 1.6 9.1 13.9 1.8 8.9 3.4 2.0 1 1 1 2 2 2 0 RNA polymerase Rpb4 Utp14 PF04615.13 CDJ40890.1 - 4.3e-05 22.3 21.3 5.2e-05 22.1 21.3 1.1 1 0 0 1 1 1 1 Utp14 protein Caldesmon PF02029.15 CDJ40890.1 - 0.0072 15.1 26.7 0.0094 14.8 26.7 1.1 1 0 0 1 1 1 1 Caldesmon PIG-U PF06728.13 CDJ40890.1 - 0.018 14.1 1.5 0.1 11.6 2.3 2.0 2 1 0 2 2 2 0 GPI transamidase subunit PIG-U SARAF PF06682.12 CDJ40890.1 - 0.025 14.2 15.0 0.038 13.6 15.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis GREB1 PF15782.5 CDJ40890.1 - 0.033 11.3 20.3 0.041 11.0 20.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zip PF02535.22 CDJ40890.1 - 0.033 13.4 14.7 0.15 11.2 9.4 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter FAM176 PF14851.6 CDJ40890.1 - 0.077 12.7 0.2 0.077 12.7 0.2 3.1 2 1 0 2 2 1 0 FAM176 family SpoIIIAH PF12685.7 CDJ40890.1 - 0.12 12.2 22.5 0.73 9.6 0.4 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein LptF_LptG PF03739.14 CDJ40890.1 - 0.15 10.9 1.0 0.25 10.1 1.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG SR-25 PF10500.9 CDJ40890.1 - 0.19 11.3 31.5 0.064 12.9 23.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF789 PF05623.12 CDJ40890.1 - 0.28 10.8 21.8 0.57 9.8 16.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF789) DUF3357 PF11837.8 CDJ40890.1 - 0.38 11.2 2.3 2.4 8.7 0.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) MSP1a PF11670.8 CDJ40890.1 - 0.53 9.5 1.7 0.49 9.7 0.3 1.5 1 1 1 2 2 2 0 Major surface protein 1a (MSP1a) DUF2052 PF09747.9 CDJ40890.1 - 0.71 10.0 29.0 0.27 11.3 1.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CCSAP PF15748.5 CDJ40890.1 - 1.8 8.6 31.5 3.3 7.8 23.4 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated LAP1C PF05609.12 CDJ40890.1 - 2.4 7.2 24.5 3.6 6.6 24.5 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4228 PF14009.6 CDJ40890.1 - 3.5 8.0 17.3 27 5.1 14.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) GAGA_bind PF06217.12 CDJ40890.1 - 3.9 7.7 21.9 5.6 7.2 15.8 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family SMYLE_N PF18615.1 CDJ40890.1 - 4 6.9 18.6 8.9 5.8 14.0 2.2 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Pkinase PF00069.25 CDJ40891.1 - 1.6e-54 185.0 0.0 1.6e-54 185.0 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ40891.1 - 1.5e-27 96.6 0.0 1.5e-27 96.6 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ40891.1 - 7.8e-06 24.9 14.0 8.6e-05 21.5 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase Utp14 PF04615.13 CDJ40891.1 - 0.0043 15.7 24.3 0.0068 15.1 24.3 1.2 1 0 0 1 1 1 1 Utp14 protein GAGA_bind PF06217.12 CDJ40891.1 - 0.37 11.0 19.8 0.79 10.0 19.8 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family PAT1 PF09770.9 CDJ40891.1 - 0.92 7.7 51.1 0.024 12.9 44.6 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TetR_C_20 PF17925.1 CDJ40891.1 - 8.6 6.7 12.3 0.63 10.4 1.4 3.4 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain ADSL_C PF10397.9 CDJ40892.1 - 0.056 14.0 2.5 0.33 11.5 0.3 2.3 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminus RTTN_N PF14726.6 CDJ40892.1 - 0.12 13.2 3.2 5.7 7.8 2.4 2.5 1 1 1 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Phosducin PF02114.16 CDJ40892.1 - 0.15 11.0 0.1 0.21 10.5 0.1 1.1 1 0 0 1 1 1 0 Phosducin TFIIF_beta PF02270.15 CDJ40893.1 - 6.1e-05 23.1 0.1 0.00034 20.7 0.1 2.1 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 CDJ40893.1 - 0.017 15.8 0.2 0.029 15.0 0.2 1.8 1 1 0 1 1 1 0 TFIIF, beta subunit N-terminus RNA_pol_Rpb1_2 PF00623.20 CDJ40896.1 - 2.5e-49 167.7 0.0 1.9e-32 112.8 0.0 2.8 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CDJ40896.1 - 9.7e-23 80.8 0.0 1.7e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CDJ40896.1 - 3.3e-16 59.5 0.8 2.2e-14 53.5 0.0 3.4 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 1 SUIM_assoc PF16619.5 CDJ40896.1 - 0.047 13.7 33.1 0.82 9.8 6.0 3.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 ANAPC_CDC26 PF10471.9 CDJ40896.1 - 0.13 13.1 30.0 0.35 11.7 3.5 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CDJ40896.1 - 1.3 8.6 34.1 0.14 11.8 5.3 3.2 3 0 0 3 3 3 0 Spt20 family RNA_pol_Rpb1_5 PF04998.17 CDJ40897.1 - 5.4e-27 94.9 0.0 1.6e-26 93.3 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 CDJ40897.1 - 1.3e-15 57.3 0.1 5.4e-15 55.3 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Asparaginase PF00710.20 CDJ40897.1 - 0.053 13.1 0.2 2.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Asparaginase, N-terminal RNA_pol_Rpb1_5 PF04998.17 CDJ40898.1 - 1.6e-44 152.3 0.0 5e-43 147.4 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 TAF4 PF05236.14 CDJ40898.1 - 0.049 13.4 0.2 0.049 13.4 0.2 3.6 2 1 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family IMUP PF15761.5 CDJ40898.1 - 0.95 10.2 45.3 0.18 12.5 5.0 3.6 2 1 0 3 3 3 0 Immortalisation up-regulated protein SDA1 PF05285.12 CDJ40898.1 - 1.5 8.2 43.2 3.3 7.0 43.2 1.6 1 0 0 1 1 1 0 SDA1 Ndc1_Nup PF09531.10 CDJ40898.1 - 6.2 5.4 12.6 13 4.3 12.6 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SART-1 PF03343.13 CDJ40899.1 - 1.6 7.2 11.8 0.07 11.7 5.6 1.8 2 0 0 2 2 2 0 SART-1 family MPP6 PF10175.9 CDJ40900.1 - 1.8 9.1 10.3 2.4 8.7 10.3 1.3 1 0 0 1 1 1 0 M-phase phosphoprotein 6 CDC27 PF09507.10 CDJ40900.1 - 9.7 5.5 18.8 11 5.2 18.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PrsW-protease PF13367.6 CDJ40901.1 - 1.4e-10 40.9 3.4 1.4e-10 40.9 3.4 3.0 3 0 0 3 3 3 2 PrsW family intramembrane metalloprotease SR-25 PF10500.9 CDJ40901.1 - 0.31 10.6 3.7 0.38 10.3 0.5 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ40903.1 - 0.0048 16.5 22.1 0.0048 16.5 22.1 6.0 4 1 1 5 5 5 2 Nuclear RNA-splicing-associated protein ANAPC_CDC26 PF10471.9 CDJ40905.1 - 0.025 15.4 10.9 0.025 15.4 10.9 4.4 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CDJ40905.1 - 0.1 12.2 28.4 0.023 14.3 11.5 3.2 3 0 0 3 3 3 0 Spt20 family MAGE PF01454.19 CDJ40905.1 - 0.35 10.6 3.4 1.1 8.9 2.7 2.1 2 0 0 2 2 2 0 MAGE family SARAF PF06682.12 CDJ40905.1 - 0.43 10.2 9.0 2.5 7.7 7.8 2.2 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis eIF-3_zeta PF05091.12 CDJ40905.1 - 0.5 9.3 6.5 0.9 8.4 6.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SUIM_assoc PF16619.5 CDJ40905.1 - 0.63 10.1 49.0 0.16 12.0 2.6 4.3 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 CTU2 PF10288.9 CDJ40905.1 - 4.2 7.6 11.6 0.15 12.3 3.1 2.8 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF4569 PF15133.6 CDJ40905.1 - 4.8 6.8 10.5 25 4.5 7.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) MMR1 PF08505.10 CDJ40905.1 - 6.2 7.0 12.7 1.3 9.2 9.0 1.8 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Suf PF05843.14 CDJ40906.1 - 0.04 13.9 0.7 0.053 13.5 0.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AdoMetDC_leader PF08132.11 CDJ40906.1 - 0.041 13.8 1.8 0.087 12.8 1.4 1.8 1 1 0 1 1 1 0 S-adenosyl-l-methionine decarboxylase leader peptide BNIP2 PF12496.8 CDJ40906.1 - 0.044 14.2 1.9 0.074 13.5 1.9 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Spt20 PF12090.8 CDJ40906.1 - 0.064 12.9 7.0 0.099 12.2 7.0 1.2 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 CDJ40906.1 - 0.23 10.6 8.4 0.43 9.7 8.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SUIM_assoc PF16619.5 CDJ40906.1 - 0.83 9.8 13.0 0.048 13.7 6.5 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Roughex PF06020.11 CDJ40906.1 - 1.1 8.3 4.3 1.5 7.9 4.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Ribosomal_60s PF00428.19 CDJ40906.1 - 3.1 8.4 8.4 2.1 9.0 1.7 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2722 PF10846.8 CDJ40906.1 - 8.2 5.2 11.2 2.3 7.1 8.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2722) Zip PF02535.22 CDJ40907.1 - 4.2 6.5 10.2 1.6 7.9 0.4 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DEAD PF00270.29 CDJ40908.1 - 2.5e-15 56.7 0.1 3.9e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ40908.1 - 0.0001 22.3 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIF_alpha PF05793.12 CDJ40908.1 - 0.09 11.4 4.0 0.12 10.9 4.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.9 CDJ40908.1 - 0.69 8.4 3.0 0.68 8.4 3.0 1.2 1 0 0 1 1 1 0 Macoilin family NUDIX PF00293.28 CDJ40909.1 - 7.4e-16 58.4 0.3 9.8e-16 58.0 0.3 1.2 1 0 0 1 1 1 1 NUDIX domain Ribosomal_60s PF00428.19 CDJ40909.1 - 7.8 7.2 12.6 15 6.3 12.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Aminotran_5 PF00266.19 CDJ40910.1 - 1.8e-62 211.5 1.9 3.2e-59 200.7 0.1 2.4 1 1 1 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 CDJ40910.1 - 0.0035 16.6 0.5 0.0035 16.6 0.5 3.2 1 1 2 3 3 3 1 Aminotransferase class I and II eIF-3_zeta PF05091.12 CDJ40910.1 - 0.31 10.0 11.1 0.62 9.0 11.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ40910.1 - 0.46 9.2 9.2 0.8 8.4 9.2 1.3 1 0 0 1 1 1 0 Presenilin DUF4820 PF16091.5 CDJ40910.1 - 0.89 8.9 13.4 0.49 9.7 11.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4638 PF15472.6 CDJ40910.1 - 0.99 9.1 7.1 0.15 11.8 2.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) DDHD PF02862.17 CDJ40910.1 - 3.5 7.7 11.0 0.27 11.4 5.1 2.1 2 1 0 2 2 2 0 DDHD domain DUF2722 PF10846.8 CDJ40910.1 - 4.3 6.2 27.2 0.012 14.6 6.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) V_ATPase_I PF01496.19 CDJ40910.1 - 9.9 3.9 10.1 16 3.2 10.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nse4_C PF08743.10 CDJ40911.1 - 4.3e-07 30.1 0.2 8.2e-05 22.8 0.0 2.6 2 0 0 2 2 2 1 Nse4 C-terminal Spt20 PF12090.8 CDJ40911.1 - 0.00058 19.6 18.3 0.00066 19.4 13.3 2.3 2 0 0 2 2 2 1 Spt20 family Secretin_N_2 PF07655.13 CDJ40911.1 - 0.0071 16.9 7.2 0.0071 16.9 7.2 3.1 3 0 0 3 3 3 1 Secretin N-terminal domain TFIIA PF03153.13 CDJ40911.1 - 0.02 14.9 25.0 0.036 14.1 25.0 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2407_C PF13373.6 CDJ40911.1 - 0.032 14.4 0.7 0.07 13.3 0.7 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain SPRY PF00622.28 CDJ40911.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 SPRY domain LMBR1 PF04791.16 CDJ40911.1 - 0.32 9.9 2.4 0.42 9.4 2.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CPSF100_C PF13299.6 CDJ40911.1 - 0.79 9.9 13.1 2.8 8.1 6.7 3.0 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Ctr PF04145.15 CDJ40911.1 - 2.4 8.8 15.6 9.4 6.8 0.0 3.4 2 1 1 3 3 3 0 Ctr copper transporter family DUF1645 PF07816.11 CDJ40911.1 - 3.2 8.3 31.9 0.019 15.6 4.4 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1645) MRP-S27 PF10037.9 CDJ40911.1 - 3.5 6.4 12.0 5 5.9 12.0 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Roughex PF06020.11 CDJ40911.1 - 3.7 6.5 6.7 6.4 5.8 6.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein GCP_N_terminal PF17681.1 CDJ40912.1 - 4e-12 46.4 0.0 3.4e-09 36.7 0.0 2.4 2 1 0 2 2 2 2 Gamma tubulin complex component N-terminal DrsE PF02635.15 CDJ40912.1 - 0.1 13.0 0.2 0.33 11.3 0.2 1.8 1 0 0 1 1 1 0 DsrE/DsrF-like family zf-C6H2 PF15801.5 CDJ40913.1 - 3.1e-13 49.8 8.4 4.2e-13 49.4 8.4 1.2 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CDJ40913.1 - 0.00031 20.7 9.4 0.00051 20.1 9.4 1.4 1 0 0 1 1 1 1 MYND finger Ribosomal_L32p PF01783.23 CDJ40913.1 - 0.17 12.2 0.8 0.33 11.2 0.8 1.5 1 0 0 1 1 1 0 Ribosomal L32p protein family PolC_DP2 PF03833.13 CDJ40913.1 - 0.76 7.6 1.7 0.79 7.5 1.7 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Aldo_ket_red PF00248.21 CDJ40914.1 - 1.3e-06 27.9 0.0 1.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family CDC45 PF02724.14 CDJ40917.1 - 3.9 5.6 7.7 4.8 5.3 7.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 CDJ40917.1 - 4.5 5.3 11.8 5.4 5.0 11.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCDC53 PF10152.9 CDJ40917.1 - 5.7 7.3 12.9 8.2 6.8 12.9 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Suf PF05843.14 CDJ40917.1 - 5.9 6.8 12.6 9.3 6.1 12.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SpoIIP PF07454.11 CDJ40917.1 - 8.3 5.8 10.9 10 5.5 10.9 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Dehydrin PF00257.19 CDJ40918.1 - 0.038 14.5 1.2 0.038 14.5 1.2 3.5 4 0 0 4 4 4 0 Dehydrin BBS1 PF14779.6 CDJ40918.1 - 0.25 10.8 1.1 3.3 7.1 0.0 2.5 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 1 Plasmodium_Vir PF05795.11 CDJ40920.1 - 0.13 11.6 1.0 0.19 11.1 1.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Cwf_Cwc_15 PF04889.12 CDJ40922.1 - 9.3 5.9 24.5 12 5.5 24.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AroM PF07302.11 CDJ40923.1 - 0.0039 16.6 1.5 0.0056 16.1 1.3 1.4 1 1 0 1 1 1 1 AroM protein Gcd10p PF04189.13 CDJ40923.1 - 0.0082 15.3 0.1 0.0091 15.1 0.1 1.0 1 0 0 1 1 1 1 Gcd10p family P22_portal PF16510.5 CDJ40923.1 - 1.3 7.5 7.3 1.5 7.3 7.3 1.0 1 0 0 1 1 1 0 Phage P22-like portal protein BAF1_ABF1 PF04684.13 CDJ40925.1 - 0.13 11.3 13.7 0.2 10.7 13.7 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SAPS PF04499.15 CDJ40925.1 - 2.5 6.8 13.6 3.4 6.4 13.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GREB1 PF15782.5 CDJ40925.1 - 5.6 3.9 24.0 7.3 3.6 24.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FSA_C PF10479.9 CDJ40927.1 - 0.0027 15.9 1.8 0.0033 15.7 1.8 1.2 1 0 0 1 1 1 1 Fragile site-associated protein C-terminus TFIIA PF03153.13 CDJ40927.1 - 0.56 10.1 14.9 0.67 9.9 14.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 CDJ40927.1 - 2.4 7.7 9.1 2.8 7.5 9.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SRP-alpha_N PF04086.13 CDJ40927.1 - 4.6 7.1 13.1 5.9 6.7 13.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 CDJ40927.1 - 5.7 5.6 6.6 6.4 5.4 6.6 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ40927.1 - 6 6.4 11.5 7.9 6.0 11.5 1.2 1 0 0 1 1 1 0 Spt20 family GHMP_kinases_C PF08544.13 CDJ40928.1 - 0.016 15.6 1.0 0.04 14.3 1.0 1.7 1 0 0 1 1 1 0 GHMP kinases C terminal SUIM_assoc PF16619.5 CDJ40928.1 - 4.1 7.5 0.0 4.1 7.5 0.0 7.2 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PA26 PF04636.13 CDJ40929.1 - 0.42 9.5 25.4 0.5 9.2 25.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) 4HB_MCP_1 PF12729.7 CDJ40930.1 - 1.1 8.8 10.5 1.8 8.0 10.5 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction FapA PF03961.13 CDJ40930.1 - 2.4 6.7 11.6 4.3 5.8 11.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A SUIM_assoc PF16619.5 CDJ40931.1 - 0.022 14.8 1.2 0.04 14.0 1.2 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Roughex PF06020.11 CDJ40931.1 - 0.17 11.0 3.0 0.28 10.2 3.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Sporozoite_P67 PF05642.11 CDJ40931.1 - 1.9 6.5 7.6 2.2 6.3 7.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF5523 PF17661.1 CDJ40932.1 - 0.011 15.5 24.8 0.086 12.5 16.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) TPR_2 PF07719.17 CDJ40932.1 - 0.18 12.0 9.7 0.44 10.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_60s PF00428.19 CDJ40932.1 - 3 8.5 16.8 0.12 13.0 3.5 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Adeno_PIX PF03955.14 CDJ40932.1 - 8.2 6.7 7.1 0.34 11.1 0.3 1.9 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) RMMBL PF07521.12 CDJ40934.1 - 1.3e-18 66.7 0.0 3.3e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain CPSF73-100_C PF11718.8 CDJ40934.1 - 1.1e-08 34.9 3.1 4.4e-06 26.4 6.7 2.7 2 1 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CDJ40934.1 - 1.1e-06 28.9 0.0 4e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain DRMBL PF07522.14 CDJ40934.1 - 0.0028 17.8 0.0 0.0059 16.8 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase R_equi_Vir PF05526.11 CDJ40935.1 - 0.068 13.0 4.9 0.07 13.0 4.9 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF3464 PF11947.8 CDJ40935.1 - 0.88 9.3 5.0 1.1 9.1 5.0 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Pex14_N PF04695.13 CDJ40935.1 - 0.91 10.2 15.7 0.97 10.1 15.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM199X PF15814.5 CDJ40935.1 - 1.2 8.1 6.9 1.2 8.1 6.9 1.0 1 0 0 1 1 1 0 Protein family FAM199X RskA PF10099.9 CDJ40935.1 - 1.5 9.0 15.8 2 8.7 15.8 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA LCIB_C_CA PF18599.1 CDJ40935.1 - 2.7 7.2 6.5 3 7.1 6.5 1.0 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases CCDC53 PF10152.9 CDJ40935.1 - 3.1 8.2 12.1 4 7.8 12.1 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Ctr PF04145.15 CDJ40935.1 - 6.7 7.3 6.1 8.1 7.1 6.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family PepSY_TM PF03929.16 CDJ40935.1 - 7.4 6.1 7.6 8.3 6.0 7.6 1.2 1 0 0 1 1 1 0 PepSY-associated TM region DUF4179 PF13786.6 CDJ40936.1 - 0.0039 17.6 0.9 0.0051 17.2 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4179) RskA PF10099.9 CDJ40936.1 - 0.05 13.9 17.4 0.073 13.4 17.4 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Gaa1 PF04114.14 CDJ40936.1 - 0.067 12.2 0.3 0.073 12.1 0.3 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component TMEM65 PF10507.9 CDJ40936.1 - 0.092 12.7 4.3 0.11 12.5 4.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 65 CD20 PF04103.15 CDJ40936.1 - 0.093 12.8 0.1 0.1 12.7 0.1 1.1 1 0 0 1 1 1 0 CD20-like family R_equi_Vir PF05526.11 CDJ40936.1 - 0.14 12.0 11.2 0.15 11.9 11.2 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein SID-1_RNA_chan PF13965.6 CDJ40936.1 - 0.28 9.5 2.5 0.28 9.5 2.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FHIPEP PF00771.20 CDJ40936.1 - 0.41 9.0 7.0 0.44 9.0 7.0 1.0 1 0 0 1 1 1 0 FHIPEP family Herpes_glycop PF01528.16 CDJ40936.1 - 0.42 9.4 6.1 0.48 9.2 6.1 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M O-antigen_lig PF13425.6 CDJ40936.1 - 0.75 8.5 1.2 0.73 8.5 1.2 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Glt_symporter PF03616.14 CDJ40936.1 - 0.79 8.3 2.6 0.88 8.2 2.6 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter Peptidase_S49_N PF08496.10 CDJ40936.1 - 0.92 9.6 15.0 1 9.4 15.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ctr PF04145.15 CDJ40936.1 - 1.1 9.8 6.7 1.3 9.7 6.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family BAF1_ABF1 PF04684.13 CDJ40936.1 - 1.2 8.1 15.1 1.3 8.0 15.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NEMP PF10225.9 CDJ40936.1 - 1.3 8.6 4.0 1.4 8.6 4.0 1.0 1 0 0 1 1 1 0 NEMP family Ureide_permease PF07168.11 CDJ40936.1 - 1.4 7.6 6.6 1.6 7.4 6.6 1.1 1 0 0 1 1 1 0 Ureide permease TERB2 PF15101.6 CDJ40936.1 - 1.5 8.8 17.1 1.6 8.8 17.1 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Connexin PF00029.19 CDJ40936.1 - 1.6 8.4 10.3 1.6 8.4 10.3 1.1 1 0 0 1 1 1 0 Connexin SpoIIP PF07454.11 CDJ40936.1 - 1.8 7.9 13.3 1.8 8.0 13.3 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EIIBC-GUT_N PF03612.14 CDJ40936.1 - 1.9 8.2 11.2 2.4 7.9 11.2 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3450 PF11932.8 CDJ40936.1 - 2.1 7.6 24.9 2.4 7.4 24.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4834 PF16118.5 CDJ40936.1 - 2.2 9.3 15.3 2.5 9.1 15.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) HA2 PF04408.23 CDJ40936.1 - 3.1 8.1 8.3 3.9 7.8 8.3 1.3 1 0 0 1 1 1 0 Helicase associated domain (HA2) Serinc PF03348.15 CDJ40936.1 - 3.3 6.5 9.0 3.3 6.5 9.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) eIF-3_zeta PF05091.12 CDJ40936.1 - 3.6 6.4 20.3 3.7 6.4 20.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PPL5 PF18168.1 CDJ40936.1 - 4 6.6 11.6 4 6.6 11.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 CDJ40936.1 - 4.2 6.0 16.8 4.4 6.0 16.8 1.0 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.8 CDJ40936.1 - 5.9 6.8 8.5 5.9 6.8 8.5 1.1 1 0 0 1 1 1 0 N-glycosylation protein AIF_C PF14721.6 CDJ40936.1 - 6.6 7.1 12.8 7.3 7.0 12.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DDHD PF02862.17 CDJ40936.1 - 7.2 6.7 14.2 7.2 6.7 14.2 1.0 1 0 0 1 1 1 0 DDHD domain Folate_carrier PF01770.18 CDJ40936.1 - 7.3 5.2 6.6 7.8 5.1 6.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier Activator_LAG-3 PF11498.8 CDJ40936.1 - 8.2 5.3 35.0 8 5.3 35.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pex14_N PF04695.13 CDJ40936.1 - 8.3 7.0 20.2 11 6.7 20.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 CDJ40936.1 - 8.3 6.1 14.8 8.3 6.1 14.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1980 PF09323.10 CDJ40936.1 - 9.1 6.2 10.4 9.5 6.1 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Neur_chan_memb PF02932.16 CDJ40936.1 - 9.6 6.2 11.4 9.3 6.2 11.4 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ni_hydr_CYTB PF01292.20 CDJ40937.1 - 0.0022 17.6 0.3 0.0022 17.6 0.3 2.0 2 0 0 2 2 2 1 Prokaryotic cytochrome b561 O-antigen_lig PF13425.6 CDJ40937.1 - 0.22 10.3 0.2 0.5 9.1 0.2 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Pdase_M17_N2 PF18295.1 CDJ40939.1 - 0.006 16.8 0.4 0.016 15.4 0.4 1.7 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 Metallophos PF00149.28 CDJ40941.1 - 0.016 15.7 0.0 0.016 15.7 0.0 1.0 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Peptidase_S28 PF05577.12 CDJ40942.1 - 2.3e-13 49.7 0.0 2.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 SARG PF15385.6 CDJ40942.1 - 0.0053 16.1 3.0 0.0058 15.9 3.0 1.0 1 0 0 1 1 1 1 Specifically androgen-regulated gene protein Ski2_N PF17911.1 CDJ40942.1 - 0.053 13.3 0.6 0.081 12.7 0.6 1.2 1 0 0 1 1 1 0 Ski2 N-terminal region DUF755 PF05501.11 CDJ40942.1 - 1.6 9.0 12.7 2.3 8.5 12.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ40942.1 - 1.7 8.2 11.5 2.1 7.9 11.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 CDJ40942.1 - 4.4 5.6 5.5 4.5 5.6 5.5 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SpoIIIAH PF12685.7 CDJ40946.1 - 9.6 6.0 18.4 6.6 6.5 6.4 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF3824 PF12868.7 CDJ40947.1 - 0.025 15.2 6.6 0.043 14.5 6.6 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) CbiD PF01888.17 CDJ40947.1 - 0.19 11.0 1.8 0.24 10.6 1.8 1.2 1 0 0 1 1 1 0 CbiD Med3 PF11593.8 CDJ40947.1 - 0.23 10.6 17.2 0.33 10.1 17.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SR-25 PF10500.9 CDJ40947.1 - 0.23 11.0 39.9 0.079 12.6 13.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Miga PF10265.9 CDJ40947.1 - 0.42 9.5 16.7 0.51 9.3 16.7 1.0 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 CDJ40947.1 - 1.2 7.7 20.0 1.5 7.3 20.0 1.1 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 CDJ40947.1 - 1.8 8.4 22.6 2 8.2 22.6 1.0 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ40947.1 - 2.5 6.9 18.7 3.2 6.5 18.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SRP-alpha_N PF04086.13 CDJ40947.1 - 3.1 7.6 17.5 3.9 7.3 17.5 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4407 PF14362.6 CDJ40947.1 - 5.9 6.2 12.2 8.1 5.7 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAT1 PF09770.9 CDJ40947.1 - 8.7 4.5 15.1 10 4.2 15.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 API5 PF05918.11 CDJ40947.1 - 9.2 4.9 10.2 15 4.3 10.2 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2339 PF10101.9 CDJ40948.1 - 3.4e-05 22.7 4.8 4.6e-05 22.2 4.8 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) RskA PF10099.9 CDJ40948.1 - 0.0021 18.4 0.8 0.0021 18.4 0.8 3.6 1 1 2 3 3 2 1 Anti-sigma-K factor rskA Mitofilin PF09731.9 CDJ40948.1 - 0.013 14.4 26.8 0.016 14.1 26.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MMR1 PF08505.10 CDJ40948.1 - 0.015 15.6 16.2 0.023 15.0 16.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Nop14 PF04147.12 CDJ40948.1 - 0.041 12.1 10.8 0.054 11.7 10.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF966 PF06136.13 CDJ40948.1 - 0.18 11.5 19.0 0.25 11.0 19.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PI3K_1B_p101 PF10486.9 CDJ40948.1 - 0.22 9.2 7.8 0.25 9.1 7.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Activator_LAG-3 PF11498.8 CDJ40948.1 - 0.24 10.3 18.5 0.42 9.5 18.5 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIF_alpha PF05793.12 CDJ40948.1 - 0.27 9.8 18.9 0.35 9.4 18.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Tub_N PF16322.5 CDJ40948.1 - 0.33 11.3 23.2 0.67 10.3 23.2 1.5 1 0 0 1 1 1 0 Tubby N-terminal DUF5385 PF17359.2 CDJ40948.1 - 0.35 10.4 5.1 0.53 9.8 5.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) NPR3 PF03666.13 CDJ40948.1 - 0.65 8.7 9.7 0.8 8.4 9.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF755 PF05501.11 CDJ40948.1 - 0.94 9.8 22.6 1.8 8.8 22.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Apt1 PF10351.9 CDJ40948.1 - 1.6 7.5 13.0 1.8 7.3 13.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 CDJ40948.1 - 1.8 5.6 16.4 2.2 5.3 16.4 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4746 PF15928.5 CDJ40948.1 - 2.9 7.3 11.1 4.1 6.7 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Plasmodium_Vir PF05795.11 CDJ40948.1 - 5 6.4 12.9 7.1 5.9 12.9 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Lin-8 PF03353.15 CDJ40948.1 - 5.1 6.6 18.5 6.9 6.1 18.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist LAP1C PF05609.12 CDJ40948.1 - 6.2 5.8 21.2 7.7 5.5 21.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_S64 PF08192.11 CDJ40948.1 - 8.2 4.8 15.2 9.5 4.6 15.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Fumble PF03630.14 CDJ40949.1 - 6.3e-15 55.2 0.0 8.9e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Fumble Peptidase_S49_N PF08496.10 CDJ40950.1 - 1.6 8.8 11.6 2 8.5 11.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CPSF100_C PF13299.6 CDJ40950.1 - 1.7 8.8 10.3 1.9 8.7 10.3 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PIP5K PF01504.18 CDJ40950.1 - 2.1 7.5 11.6 2.2 7.4 11.6 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Sec62 PF03839.16 CDJ40950.1 - 4.1 6.8 8.7 4.6 6.7 8.7 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Kei1 PF08552.11 CDJ40950.1 - 4.2 7.2 8.1 5.1 6.9 8.1 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RR_TM4-6 PF06459.12 CDJ40950.1 - 4.5 7.0 12.3 5.2 6.8 12.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 CDJ40950.1 - 5.1 6.5 12.6 6 6.2 12.6 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2828 PF11443.8 CDJ40950.1 - 5.6 4.9 13.7 6.2 4.8 13.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Connexin PF00029.19 CDJ40950.1 - 5.7 6.6 11.1 6.6 6.4 11.1 1.0 1 0 0 1 1 1 0 Connexin FliP PF00813.20 CDJ40950.1 - 9.6 6.0 6.8 11 5.8 6.8 1.0 1 0 0 1 1 1 0 FliP family SUIM_assoc PF16619.5 CDJ40951.1 - 3.3 7.9 22.4 0.16 12.1 4.6 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 baeRF_family10 PF18854.1 CDJ40952.1 - 0.02 15.2 3.3 0.02 15.2 3.3 1.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 Activator_LAG-3 PF11498.8 CDJ40952.1 - 0.23 10.4 20.2 0.34 9.8 20.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TraG_N PF07916.11 CDJ40952.1 - 2 7.1 3.1 3.2 6.5 3.1 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Uso1_p115_C PF04871.13 CDJ40952.1 - 5.6 7.4 9.8 13 6.1 9.8 1.7 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region SUIM_assoc PF16619.5 CDJ40954.1 - 1.6 8.8 16.2 0.6 10.2 2.1 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 CDJ40955.1 - 9.7 6.9 16.2 1 10.0 9.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein UvrD-helicase PF00580.21 CDJ40957.1 - 0.057 12.9 10.5 0.062 12.8 10.5 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain X8 PF07983.13 CDJ40957.1 - 0.91 10.3 5.0 0.4 11.4 1.4 2.1 2 0 0 2 2 2 0 X8 domain YfhO PF09586.10 CDJ40957.1 - 3.1 5.9 7.2 3.6 5.7 7.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO BPL_N PF09825.9 CDJ40957.1 - 7 5.6 9.1 8.5 5.3 9.1 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Band_3_cyto PF07565.13 CDJ40957.1 - 7.3 6.3 16.1 9.6 5.9 16.1 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Rpp20 PF12328.8 CDJ40957.1 - 8.9 6.3 17.7 31 4.5 17.2 2.1 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P K_channel_TID PF07941.11 CDJ40958.1 - 0.3 11.6 9.0 0.39 11.2 9.0 1.1 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain ANAPC_CDC26 PF10471.9 CDJ40960.1 - 0.044 14.6 10.7 0.044 14.6 10.7 5.3 2 1 1 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Pox_A3L PF05288.11 CDJ40960.1 - 0.084 12.9 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A3L Protein TFIIA PF03153.13 CDJ40961.1 - 1.6 8.6 18.6 2 8.3 18.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TTL PF03133.15 CDJ40962.1 - 6.6e-29 101.0 0.1 3.8e-28 98.5 0.0 2.2 4 0 0 4 4 4 1 Tubulin-tyrosine ligase family Fez1 PF06818.15 CDJ40962.1 - 5.6e-05 23.7 6.5 0.00011 22.7 6.5 1.4 1 0 0 1 1 1 1 Fez1 Fmp27_WPPW PF10359.9 CDJ40963.1 - 0.0078 15.1 1.2 0.0078 15.1 1.2 3.2 2 1 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain TMF_TATA_bd PF12325.8 CDJ40963.1 - 7.4 6.8 48.7 0.039 14.2 11.6 4.5 4 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding TPR_1 PF00515.28 CDJ40964.1 - 4.5e-08 32.6 18.3 0.0006 19.5 0.4 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ40964.1 - 9.2e-06 25.3 8.9 0.045 13.8 0.2 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ40964.1 - 1.1e-05 25.1 22.6 0.012 15.7 2.5 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ40964.1 - 0.23 11.8 13.5 9.5 6.7 0.4 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PH_11 PF15413.6 CDJ40964.1 - 0.66 10.4 4.2 0.39 11.1 0.2 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain EIIBC-GUT_N PF03612.14 CDJ40964.1 - 3.4 7.4 16.2 2 8.1 5.4 2.5 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus PcfK PF14058.6 CDJ40964.1 - 6.3 7.1 18.2 1.1 9.6 11.3 2.5 2 0 0 2 2 2 0 PcfK-like protein RskA PF10099.9 CDJ40965.1 - 0.00041 20.7 0.8 0.00047 20.5 0.8 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA RAM PF15320.6 CDJ40965.1 - 0.01 16.4 1.8 0.016 15.8 1.8 1.2 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Spt20 PF12090.8 CDJ40965.1 - 0.58 9.7 9.7 0.71 9.4 9.7 1.1 1 0 0 1 1 1 0 Spt20 family Dpy-30 PF05186.13 CDJ40969.1 - 4.4e-12 45.5 0.1 8.1e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 Dpy-30 motif DUF1499 PF07386.11 CDJ40972.1 - 1.5 9.4 4.4 12 6.4 0.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1499) Kei1 PF08552.11 CDJ40974.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.3 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 BTB PF00651.31 CDJ40975.1 - 5.6e-11 42.7 0.0 5.1e-10 39.6 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain UPF0565 PF10561.9 CDJ40975.1 - 0.15 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 BTB PF00651.31 CDJ40978.1 - 6.4e-11 42.5 0.0 5.8e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain UPF0565 PF10561.9 CDJ40978.1 - 0.15 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DEAD PF00270.29 CDJ40979.1 - 6.7e-44 149.7 0.1 3.9e-43 147.3 0.0 2.4 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ40979.1 - 9.6e-31 106.4 0.0 4.7e-30 104.2 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ40979.1 - 2e-06 27.9 0.0 1.1e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 CDJ40979.1 - 0.0012 18.2 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain Aldolase PF01081.19 CDJ40979.1 - 0.094 12.1 0.0 1.1 8.7 0.0 2.4 3 0 0 3 3 3 0 KDPG and KHG aldolase RCDG1 PF15725.5 CDJ40979.1 - 0.3 11.5 1.6 0.78 10.2 1.6 1.6 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein zf-CCHC PF00098.23 CDJ40979.1 - 4.6 7.5 8.6 0.36 11.0 3.6 1.8 2 0 0 2 2 2 0 Zinc knuckle Galactosyl_T PF01762.21 CDJ40984.1 - 8.4e-44 149.7 0.0 1e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 CDJ40984.1 - 2.9e-05 23.6 0.0 4.3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CDJ40985.1 - 3.2e-34 118.5 0.0 4.2e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase MMR_HSR1 PF01926.23 CDJ40986.1 - 1.6e-09 37.8 0.0 3.5e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ40986.1 - 0.00028 20.5 0.0 0.98 8.9 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CDJ40986.1 - 0.0006 19.9 0.7 0.042 13.9 0.2 2.5 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 CDJ40986.1 - 0.0013 18.6 0.1 0.079 12.9 0.1 2.6 2 1 0 2 2 2 1 RsgA GTPase Spore_IV_A PF09547.10 CDJ40986.1 - 0.0057 15.6 0.0 0.0085 15.1 0.0 1.1 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) G-alpha PF00503.20 CDJ40986.1 - 0.043 13.0 0.0 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 CDJ40986.1 - 0.11 12.3 0.0 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain FeoB_N PF02421.18 CDJ40986.1 - 0.15 11.6 0.3 9.8 5.7 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B ATPase_2 PF01637.18 CDJ40986.1 - 0.29 11.0 0.3 0.64 9.9 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SR-25 PF10500.9 CDJ40987.1 - 0.012 15.3 11.7 0.018 14.7 11.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.11 CDJ40987.1 - 0.048 13.5 3.9 0.066 13.1 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Fmp27_WPPW PF10359.9 CDJ40987.1 - 0.095 11.5 2.9 0.14 11.0 2.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Lin-8 PF03353.15 CDJ40987.1 - 0.2 11.2 3.7 0.29 10.7 3.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sporozoite_P67 PF05642.11 CDJ40987.1 - 4.8 5.2 7.5 9.3 4.2 7.5 1.6 1 1 0 1 1 1 0 Sporozoite P67 surface antigen MACPF PF01823.19 CDJ40988.1 - 4.2e-42 144.6 0.2 5.5e-42 144.2 0.2 1.1 1 0 0 1 1 1 1 MAC/Perforin domain Pkinase PF00069.25 CDJ40988.1 - 4.9e-23 81.8 0.0 1e-22 80.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ40988.1 - 6.7e-06 25.6 0.0 1.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Baculo_PEP_C PF04513.12 CDJ40988.1 - 0.0044 17.1 0.1 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5419 PF17441.2 CDJ40988.1 - 0.13 12.4 0.5 0.59 10.3 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5419) FtsL PF04999.13 CDJ40990.1 - 0.018 15.0 11.6 0.054 13.5 11.6 1.7 1 1 0 1 1 1 0 Cell division protein FtsL Sperm_Ag_HE2 PF05324.13 CDJ40990.1 - 0.47 10.9 5.4 0.55 10.7 5.4 1.1 1 0 0 1 1 1 0 Sperm antigen HE2 FAM150 PF15129.6 CDJ40990.1 - 0.82 9.8 7.9 0.95 9.6 7.9 1.1 1 0 0 1 1 1 0 FAM150 family ExbD PF02472.16 CDJ40990.1 - 1.4 9.1 8.2 1.7 8.8 8.2 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR FliP PF00813.20 CDJ40990.1 - 2.6 7.9 5.5 2.6 7.9 5.5 1.0 1 0 0 1 1 1 0 FliP family Conotoxin PF02950.17 CDJ40990.1 - 4.2 8.5 6.9 9.2 7.4 6.9 1.7 1 1 0 1 1 1 0 Conotoxin TMEM51 PF15345.6 CDJ40990.1 - 4.9 6.9 10.7 5.6 6.7 10.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.6 CDJ40990.1 - 7.1 7.6 6.0 11 7.0 6.0 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Dus PF01207.17 CDJ40992.1 - 0.00052 19.2 0.0 0.0014 17.8 0.0 1.7 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) CAF1 PF04857.20 CDJ40992.1 - 8.5 5.4 9.8 12 4.9 9.8 1.3 1 1 0 1 1 1 0 CAF1 family ribonuclease PIN_6 PF17146.4 CDJ40993.1 - 4e-18 65.7 0.0 7.8e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 CDJ40993.1 - 4.9e-18 65.1 0.7 8e-18 64.4 0.7 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.11 CDJ40993.1 - 0.057 13.1 1.5 2.8 7.7 0.1 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain OrfB_Zn_ribbon PF07282.11 CDJ40993.1 - 0.17 11.9 0.7 0.31 11.0 0.7 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Nudix_N_2 PF14803.6 CDJ40993.1 - 0.19 11.7 2.0 4.2 7.4 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal Spt20 PF12090.8 CDJ40993.1 - 1 8.9 5.8 1.3 8.5 4.5 1.8 2 0 0 2 2 2 0 Spt20 family NINJA_B PF16136.5 CDJ40993.1 - 6.9 7.1 8.4 5.2 7.5 5.8 2.2 2 0 0 2 2 2 0 Putative nuclear localisation signal SUIM_assoc PF16619.5 CDJ40993.1 - 9.9 6.3 13.4 3.3 7.8 9.4 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HEAT PF02985.22 CDJ40994.1 - 0.037 14.3 9.2 4.1 7.9 0.2 6.6 5 0 0 5 5 5 0 HEAT repeat PUB PF09409.10 CDJ40994.1 - 0.072 13.0 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 PUB domain DUF1126 PF06565.12 CDJ40995.1 - 6.5e-33 112.7 0.6 1e-28 99.2 0.0 2.1 2 0 0 2 2 2 2 DUF1126 PH-like domain EF-hand_8 PF13833.6 CDJ40996.1 - 1.3e-08 34.6 0.5 3.2e-08 33.3 0.5 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ40996.1 - 1.7e-07 30.3 0.8 0.00011 21.5 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDJ40996.1 - 2e-07 31.4 1.1 4.5e-07 30.2 0.2 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ40996.1 - 1.9e-05 24.2 0.2 0.0078 16.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ40996.1 - 0.01 15.3 0.1 0.036 13.6 0.0 1.9 2 0 0 2 2 2 0 EF hand ketoacyl-synt PF00109.26 CDJ40997.1 - 1.4e-16 60.9 0.0 2.3e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ketoacyl-synt PF00109.26 CDJ40998.1 - 1.3e-221 732.6 6.9 1.5e-67 227.9 0.0 4.7 4 0 0 4 4 4 4 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CDJ40998.1 - 1.1e-143 470.6 12.2 1.4e-36 125.0 0.2 4.9 4 0 0 4 4 4 4 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 CDJ40998.1 - 8.1e-106 351.7 0.3 5.7e-52 176.2 0.1 3.4 3 0 0 3 3 3 2 KR domain Acyl_transf_1 PF00698.21 CDJ40998.1 - 1.3e-79 268.0 7.1 1.9e-39 136.0 1.5 2.5 2 0 0 2 2 2 2 Acyl transferase domain PP-binding PF00550.25 CDJ40998.1 - 8.9e-36 122.1 4.1 5.9e-12 45.8 0.5 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site PS-DH PF14765.6 CDJ40998.1 - 4e-35 121.5 0.0 9.8e-35 120.2 0.0 1.6 1 1 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.12 CDJ40998.1 - 5.2e-28 97.9 0.0 2.1e-25 89.4 0.0 3.1 3 0 0 3 3 3 1 Male sterility protein adh_short PF00106.25 CDJ40998.1 - 1.1e-21 77.2 0.0 5.3e-12 45.6 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase KAsynt_C_assoc PF16197.5 CDJ40998.1 - 2.5e-18 66.6 0.2 3.9e-05 24.1 0.0 3.8 3 0 0 3 3 3 3 Ketoacyl-synthetase C-terminal extension adh_short_C2 PF13561.6 CDJ40998.1 - 1.1e-15 57.8 0.0 3.2e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CDJ40998.1 - 8.2e-05 22.2 1.9 0.0015 18.0 0.0 3.5 3 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family DUF4426 PF14467.6 CDJ40998.1 - 0.0005 20.0 0.2 7.1 6.6 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4426) GDP_Man_Dehyd PF16363.5 CDJ40998.1 - 0.0034 16.8 0.0 0.008 15.6 0.0 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase COMP PF11598.8 CDJ40998.1 - 0.0049 17.3 2.9 2.6 8.6 0.2 2.6 2 0 0 2 2 2 2 Cartilage oligomeric matrix protein Polysacc_synt_2 PF02719.15 CDJ40998.1 - 0.0056 15.9 0.0 0.28 10.3 0.0 3.3 4 0 0 4 4 4 1 Polysaccharide biosynthesis protein Glyco_trans_4_3 PF12000.8 CDJ40998.1 - 0.074 12.7 0.0 17 5.0 0.0 2.8 2 0 0 2 2 2 0 Glycosyl transferase family 4 group Thiolase_N PF00108.23 CDJ40998.1 - 0.1 11.9 12.1 1.9 7.8 0.1 4.3 4 0 0 4 4 4 0 Thiolase, N-terminal domain Syntaxin-6_N PF09177.11 CDJ41000.1 - 5.9e-19 68.5 8.6 5.2e-18 65.4 1.2 2.2 2 0 0 2 2 2 2 Syntaxin 6, N-terminal Peptidase_M61 PF05299.12 CDJ41000.1 - 0.098 13.1 1.4 0.23 11.8 0.2 2.0 1 1 1 2 2 2 0 M61 glycyl aminopeptidase Nup88 PF10168.9 CDJ41000.1 - 0.13 10.1 9.8 0.14 9.9 9.8 1.1 1 0 0 1 1 1 0 Nuclear pore component BLOC1_2 PF10046.9 CDJ41000.1 - 0.69 10.2 11.0 0.2 12.0 0.6 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SUIM_assoc PF16619.5 CDJ41000.1 - 2.1 8.4 20.7 0.3 11.2 1.2 3.4 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SNARE PF05739.19 CDJ41000.1 - 4.7 7.3 8.7 0.95 9.5 3.9 2.3 2 0 0 2 2 2 0 SNARE domain Exonuc_VII_L PF02601.15 CDJ41000.1 - 4.8 6.6 16.8 8.2 5.9 16.8 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit ALMT PF11744.8 CDJ41000.1 - 5.2 5.8 6.9 6.3 5.5 6.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Ribosomal_L23 PF00276.20 CDJ41001.1 - 5.6e-13 49.1 0.9 5.6e-13 49.1 0.9 2.4 2 2 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 CDJ41001.1 - 0.00026 21.1 18.9 0.0006 20.0 16.9 2.6 2 2 0 2 2 2 1 Ribosomal protein L23, N-terminal domain TusA PF01206.17 CDJ41001.1 - 0.0052 16.6 0.1 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 Sulfurtransferase TusA NPR3 PF03666.13 CDJ41001.1 - 0.081 11.7 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pro_isomerase PF00160.21 CDJ41002.1 - 8.6e-42 143.1 0.0 1.1e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Coilin_N PF15862.5 CDJ41003.1 - 0.041 13.7 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus WD40 PF00400.32 CDJ41004.1 - 9.9e-07 29.4 10.9 0.0046 17.8 0.0 4.1 4 1 0 4 4 4 2 WD domain, G-beta repeat TFIIA PF03153.13 CDJ41004.1 - 1.8 8.5 15.1 1.1 9.2 12.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HEAT PF02985.22 CDJ41005.1 - 9.6e-08 31.7 19.8 0.023 14.9 0.1 6.8 6 0 0 6 6 6 3 HEAT repeat DUF4042 PF13251.6 CDJ41005.1 - 4.4 7.0 5.6 7.8 6.2 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) RRS1 PF04939.12 CDJ41006.1 - 1e-35 123.0 5.9 5e-35 120.8 5.9 2.0 1 1 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Roughex PF06020.11 CDJ41007.1 - 7.7e-05 22.0 5.7 7.7e-05 22.0 5.7 2.2 2 0 0 2 2 2 1 Drosophila roughex protein FapA PF03961.13 CDJ41007.1 - 0.092 11.3 3.9 0.14 10.8 3.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 CDJ41007.1 - 0.12 10.3 9.9 0.18 9.7 9.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spt20 PF12090.8 CDJ41007.1 - 0.15 11.7 25.9 0.33 10.5 16.6 2.2 2 0 0 2 2 2 0 Spt20 family Anoctamin PF04547.12 CDJ41007.1 - 0.16 10.7 2.0 0.27 10.0 2.0 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel Peptidase_S49_N PF08496.10 CDJ41007.1 - 0.54 10.3 12.4 0.79 9.8 8.8 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Allexi_40kDa PF05549.11 CDJ41007.1 - 0.97 8.9 8.3 2.5 7.5 8.3 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein Cwf_Cwc_15 PF04889.12 CDJ41007.1 - 1.1 9.0 19.4 0.25 11.0 13.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF1645 PF07816.11 CDJ41007.1 - 1.4 9.5 29.4 0.83 10.2 10.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1645) LIM_bind PF01803.16 CDJ41007.1 - 1.4 8.4 12.2 0.68 9.4 7.9 2.1 2 0 0 2 2 2 0 LIM-domain binding protein Fmp27_WPPW PF10359.9 CDJ41007.1 - 2.1 7.1 20.6 0.21 10.4 16.0 1.5 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Jnk-SapK_ap_N PF09744.9 CDJ41007.1 - 3.2 7.9 27.2 0.15 12.3 19.9 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 PAT1 PF09770.9 CDJ41007.1 - 3.4 5.8 21.4 4.8 5.3 21.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDRGK PF09756.9 CDJ41007.1 - 3.8 7.1 25.6 0.14 11.8 15.2 2.1 2 0 0 2 2 2 0 DDRGK domain Pinin_SDK_memA PF04696.13 CDJ41007.1 - 4.3 7.4 29.7 1.5 8.9 20.5 2.4 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region ALMT PF11744.8 CDJ41007.1 - 5.4 5.7 17.3 0.36 9.6 12.3 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter MAT1 PF06391.13 CDJ41007.1 - 5.6 6.7 20.9 1.9 8.3 14.1 2.4 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF4770 PF15994.5 CDJ41007.1 - 6.1 7.0 13.7 1.9 8.7 7.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Kinase-like PF14531.6 CDJ41008.1 - 1e-09 38.1 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SUIM_assoc PF16619.5 CDJ41009.1 - 3.9 7.6 9.1 7.3 6.7 5.3 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SLATT_1 PF18181.1 CDJ41010.1 - 5.8 6.9 10.8 5.4 7.0 6.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Smg4_UPF3 PF03467.15 CDJ41011.1 - 0.013 15.5 0.2 0.013 15.5 0.2 2.1 1 1 1 2 2 2 0 Smg-4/UPF3 family USP8_interact PF08941.10 CDJ41011.1 - 0.11 12.3 6.1 0.14 12.0 6.1 1.0 1 0 0 1 1 1 0 USP8 interacting MTP18 PF10558.9 CDJ41011.1 - 0.15 12.0 1.9 0.16 11.9 1.9 1.0 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Androgen_recep PF02166.16 CDJ41011.1 - 0.17 10.7 13.6 0.19 10.5 13.6 1.1 1 0 0 1 1 1 0 Androgen receptor Tim54 PF11711.8 CDJ41011.1 - 0.31 9.8 6.4 0.36 9.6 6.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Roughex PF06020.11 CDJ41011.1 - 0.41 9.7 7.3 0.46 9.5 7.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF2722 PF10846.8 CDJ41011.1 - 0.78 8.6 12.8 0.82 8.5 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pap_E4 PF02711.14 CDJ41011.1 - 1.8 9.6 9.8 1.5 9.8 9.0 1.3 1 1 0 1 1 1 0 E4 protein CLN3 PF02487.17 CDJ41011.1 - 2.1 7.3 3.4 2.1 7.3 3.4 1.0 1 0 0 1 1 1 0 CLN3 protein CBP4 PF07960.11 CDJ41011.1 - 2.6 7.9 15.5 1.9 8.3 0.2 2.1 1 1 1 2 2 2 0 CBP4 PepSY_TM PF03929.16 CDJ41011.1 - 3.6 7.2 5.2 3.8 7.1 5.2 1.1 1 0 0 1 1 1 0 PepSY-associated TM region DUF4834 PF16118.5 CDJ41011.1 - 3.6 8.6 6.9 4.8 8.2 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 CDJ41011.1 - 3.7 7.5 8.1 4 7.4 8.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4108 PF13390.6 CDJ41012.1 - 0.15 11.9 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4108) Asn_synthase PF00733.21 CDJ41013.1 - 3.8e-62 211.0 0.0 3.4e-38 132.2 0.0 2.0 1 1 1 2 2 2 2 Asparagine synthase SRAP PF02586.14 CDJ41014.1 - 3.1e-19 69.4 9.7 3.3e-18 66.0 9.7 2.3 1 1 0 1 1 1 1 SOS response associated peptidase (SRAP) MAT1 PF06391.13 CDJ41014.1 - 0.014 15.3 17.5 0.44 10.4 9.0 2.4 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 ORC_WH_C PF18137.1 CDJ41014.1 - 0.038 14.1 0.5 0.038 14.1 0.5 3.0 2 1 0 2 2 2 0 Origin recognition complex winged helix C-terminal SLC12 PF03522.15 CDJ41014.1 - 1.5 7.8 13.7 2.9 6.8 4.7 2.1 2 0 0 2 2 2 0 Solute carrier family 12 TEX19 PF15553.6 CDJ41014.1 - 1.5 8.8 10.4 5.8 6.9 0.2 2.7 2 0 0 2 2 2 0 Testis-expressed protein 19 DUF2347 PF09804.9 CDJ41014.1 - 3.3 7.2 8.0 0.56 9.7 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Otopetrin PF03189.13 CDJ41014.1 - 6.9 5.4 7.8 5.9 5.6 0.9 2.2 2 0 0 2 2 2 0 Otopetrin Ribosomal_60s PF00428.19 CDJ41015.1 - 0.0076 16.8 13.5 0.0076 16.8 13.5 11.7 6 3 3 9 9 9 2 60s Acidic ribosomal protein Lipase_3 PF01764.25 CDJ41015.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) SUIM_assoc PF16619.5 CDJ41015.1 - 1.9 8.6 0.0 1.9 8.6 0.0 6.2 2 1 3 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Sec62 PF03839.16 CDJ41015.1 - 3.5 7.1 9.4 8.9 5.7 9.4 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 V_ATPase_I PF01496.19 CDJ41015.1 - 4.3 5.1 14.3 7.2 4.4 14.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paramyxo_ncap PF00973.19 CDJ41015.1 - 7.3 5.4 7.5 13 4.6 7.5 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DEAD PF00270.29 CDJ41016.1 - 1.6e-24 86.6 21.8 4.3e-24 85.2 0.2 3.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase Draxin PF15550.6 CDJ41016.1 - 0.0013 18.6 5.4 0.0013 18.6 5.4 3.5 3 1 0 3 3 3 1 Draxin Miga PF10265.9 CDJ41016.1 - 2.1 7.2 33.2 0.0081 15.2 9.2 3.3 3 0 0 3 3 3 0 Mitoguardin DUF4701 PF15773.5 CDJ41017.1 - 0.0015 17.6 2.0 0.002 17.2 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4701) DUF3446 PF11928.8 CDJ41017.1 - 0.012 15.9 5.4 0.026 14.8 5.4 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain IMUP PF15761.5 CDJ41017.1 - 1.1 9.9 10.1 2.2 9.0 10.1 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Hom_end_hint PF05203.16 CDJ41018.1 - 2.3 8.1 9.6 1 9.2 5.9 2.0 2 0 0 2 2 2 0 Hom_end-associated Hint DUF3638 PF12340.8 CDJ41019.1 - 3.8e-22 78.7 0.1 5e-22 78.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) ResIII PF04851.15 CDJ41019.1 - 0.013 15.5 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TFIIA PF03153.13 CDJ41020.1 - 0.069 13.1 14.2 0.08 12.9 14.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ41020.1 - 0.088 12.4 6.9 0.13 11.9 6.9 1.2 1 0 0 1 1 1 0 Spt20 family DUF775 PF05603.12 CDJ41020.1 - 7.2 6.1 6.9 13 5.3 6.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF775) Rad52_Rad22 PF04098.15 CDJ41020.1 - 7.5 6.5 8.3 0.67 9.9 0.3 2.3 2 0 0 2 2 2 0 Rad52/22 family double-strand break repair protein Corona_nucleoca PF00937.18 CDJ41022.1 - 0.00028 20.0 6.2 0.00028 20.0 6.2 2.2 1 1 1 2 2 2 1 Coronavirus nucleocapsid protein Dehydrin PF00257.19 CDJ41022.1 - 0.0076 16.8 0.6 0.0076 16.8 0.6 5.0 4 1 0 5 5 5 1 Dehydrin GREB1 PF15782.5 CDJ41022.1 - 2.4 5.1 7.9 3.9 4.5 7.9 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ41022.1 - 8 5.9 10.6 0.51 9.9 3.3 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist RNA_POL_M_15KD PF02150.16 CDJ41023.1 - 3.2e-07 30.1 6.1 3.2e-07 30.1 6.1 2.0 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 CDJ41023.1 - 1.6e-05 24.6 0.7 1.6e-05 24.6 0.7 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Nudc_N PF14050.6 CDJ41023.1 - 0.11 12.5 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. PHD PF00628.29 CDJ41023.1 - 1.1 9.2 10.1 7.4 6.6 2.7 3.1 2 1 0 2 2 2 0 PHD-finger zf-IS66 PF13005.7 CDJ41023.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.3 3 1 1 4 4 4 0 zinc-finger binding domain of transposase IS66 IBR PF01485.21 CDJ41023.1 - 1.3 9.3 9.0 1.4 9.2 0.5 2.9 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain zinc_ribbon_10 PF10058.9 CDJ41023.1 - 1.6 8.5 5.3 11 5.9 0.4 3.1 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Ogr_Delta PF04606.12 CDJ41023.1 - 2.3 8.3 6.0 2.7 8.0 1.9 2.8 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger CpXC PF14353.6 CDJ41023.1 - 7.5 6.6 7.9 0.46 10.5 0.5 2.6 2 2 1 3 3 3 0 CpXC protein HECT PF00632.25 CDJ41025.1 - 1.9e-36 126.1 0.0 2.7e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DisA-linker PF10635.9 CDJ41026.1 - 0.061 13.1 0.0 0.085 12.6 0.0 1.1 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Pkinase PF00069.25 CDJ41027.1 - 0.0004 19.8 0.1 0.0007 19.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain YceD PF02620.17 CDJ41027.1 - 0.04 14.1 0.1 0.068 13.3 0.1 1.4 1 0 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD T2SSM_b PF10741.9 CDJ41027.1 - 0.072 12.9 0.3 0.072 12.9 0.3 3.6 4 1 0 5 5 5 0 Type II secretion system (T2SS), protein M subtype b Velvet PF11754.8 CDJ41027.1 - 0.15 12.0 11.6 0.14 12.0 9.4 2.1 1 1 1 2 2 2 0 Velvet factor Secretin_N_2 PF07655.13 CDJ41028.1 - 0.3 11.7 25.8 3.4 8.3 5.2 3.4 3 0 0 3 3 3 0 Secretin N-terminal domain Peptidase_C2 PF00648.21 CDJ41029.1 - 1.6e-06 27.4 0.0 1.9e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease K_channel_TID PF07941.11 CDJ41029.1 - 0.76 10.3 7.5 1.5 9.3 7.5 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Dus PF01207.17 CDJ41032.1 - 3.1e-12 46.2 0.5 2.3e-11 43.3 0.1 2.4 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) DUF3446 PF11928.8 CDJ41032.1 - 7.1e-07 29.5 14.0 0.0015 18.8 4.7 2.9 3 0 0 3 3 3 2 Early growth response N-terminal domain His_biosynth PF00977.21 CDJ41032.1 - 0.14 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein IMPDH PF00478.25 CDJ41032.1 - 0.15 11.0 0.8 0.21 10.5 0.8 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain PLU-1 PF08429.11 CDJ41033.1 - 8.4e-22 77.8 0.0 1.1e-18 67.6 0.0 2.6 2 1 0 2 2 2 2 PLU-1-like protein AP2 PF00847.20 CDJ41034.1 - 0.00094 19.4 1.0 0.00094 19.4 1.0 2.3 2 0 0 2 2 2 1 AP2 domain TFIIS_C PF01096.18 CDJ41037.1 - 2.5e-19 68.8 4.6 2.5e-19 68.8 4.6 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CDJ41037.1 - 2.1e-09 37.1 9.7 2.2e-09 37.0 1.6 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zinc_ribbon_10 PF10058.9 CDJ41037.1 - 0.00017 21.2 6.0 0.022 14.5 0.4 2.6 2 1 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein DUF3716 PF12511.8 CDJ41037.1 - 0.00036 20.5 0.5 0.00036 20.5 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) Zn_Tnp_IS1595 PF12760.7 CDJ41037.1 - 0.00075 19.4 9.1 0.028 14.4 1.6 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain zf-RRPl_C4 PF17026.5 CDJ41037.1 - 0.0034 17.5 2.0 0.0049 17.0 2.0 1.3 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type DUF2387 PF09526.10 CDJ41037.1 - 0.008 16.3 4.0 0.058 13.6 0.2 2.2 1 1 1 2 2 2 1 Probable metal-binding protein (DUF2387) zf-C4_Topoisom PF01396.19 CDJ41037.1 - 0.015 15.1 6.6 1.3 8.9 0.3 3.0 2 2 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger TF_Zn_Ribbon PF08271.12 CDJ41037.1 - 0.034 13.7 9.1 0.84 9.2 1.2 2.4 2 1 0 2 2 2 0 TFIIB zinc-binding zinc-ribbons_6 PF07191.12 CDJ41037.1 - 0.17 11.9 7.5 0.24 11.4 0.3 2.6 2 1 1 3 3 3 0 zinc-ribbons Terminase_GpA PF05876.12 CDJ41037.1 - 0.19 10.3 1.1 0.31 9.5 1.1 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) FAM163 PF15069.6 CDJ41037.1 - 0.26 11.7 2.5 0.3 11.5 0.7 1.9 1 1 1 2 2 2 0 FAM163 family DpnI PF06044.12 CDJ41037.1 - 0.29 10.8 5.2 0.15 11.7 0.4 2.0 1 1 0 2 2 2 0 Dam-replacing family HypA PF01155.19 CDJ41037.1 - 0.36 10.9 4.7 0.14 12.1 0.3 2.3 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_2 PF03107.16 CDJ41037.1 - 0.38 11.1 6.2 5.4 7.4 0.1 2.9 3 0 0 3 3 3 0 C1 domain Baculo_LEF5_C PF11792.8 CDJ41037.1 - 2.5 7.9 5.3 0.57 9.9 1.3 1.9 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Pyr_redox_2 PF07992.14 CDJ41038.1 - 3.5e-17 62.6 0.0 4.2e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDJ41038.1 - 0.00066 18.9 3.1 0.0099 15.0 2.8 2.0 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 CDJ41038.1 - 0.00087 18.6 0.0 0.00092 18.6 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CDJ41038.1 - 0.0014 17.4 0.4 0.0065 15.2 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.6 CDJ41038.1 - 0.0029 16.8 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 CDJ41038.1 - 0.01 15.2 0.5 0.015 14.6 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 CDJ41038.1 - 0.021 13.9 0.7 0.027 13.5 0.7 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CDJ41038.1 - 0.072 12.3 1.9 1.3 8.2 1.6 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4834 PF16118.5 CDJ41039.1 - 0.14 13.1 6.8 0.31 12.0 3.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ41039.1 - 0.43 9.3 3.3 0.51 9.0 3.3 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ41039.1 - 0.44 10.1 25.1 0.54 9.8 15.2 2.1 2 0 0 2 2 2 0 Spt20 family SAPIS-gp6 PF16722.5 CDJ41039.1 - 0.86 10.1 12.7 0.064 13.7 5.1 2.2 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus Kei1 PF08552.11 CDJ41039.1 - 0.91 9.4 4.6 1.2 9.0 4.6 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RAB3GAP2_N PF14655.6 CDJ41039.1 - 0.99 8.6 8.5 0.62 9.3 3.6 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus tRNA_synt_1c_R2 PF04557.15 CDJ41039.1 - 1.1 10.2 7.4 24 6.0 0.0 2.1 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF2722 PF10846.8 CDJ41039.1 - 6.8 5.5 20.8 9 5.1 16.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) XRN_N PF03159.18 CDJ41039.1 - 10 5.5 8.6 0.94 8.9 4.6 1.4 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus DUF4733 PF15878.5 CDJ41040.1 - 0.26 11.8 0.1 0.26 11.8 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4733) DUF4820 PF16091.5 CDJ41041.1 - 2.3 7.5 16.1 0.52 9.6 1.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4820) RskA PF10099.9 CDJ41041.1 - 2.5 8.4 43.9 1.7 8.9 14.5 3.8 1 1 0 2 2 2 0 Anti-sigma-K factor rskA Nop16 PF09420.10 CDJ41042.1 - 0.00081 19.5 5.6 0.096 12.7 0.1 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 Neur_chan_memb PF02932.16 CDJ41045.1 - 5.1 7.1 8.5 7.5 6.5 8.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MFS_1 PF07690.16 CDJ41046.1 - 1.8e-18 66.6 32.0 1.8e-18 66.6 32.0 3.1 2 1 1 3 3 3 1 Major Facilitator Superfamily OATP PF03137.20 CDJ41046.1 - 8.7e-12 44.1 24.0 1.4e-11 43.4 14.4 3.9 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DDHD PF02862.17 CDJ41046.1 - 2.4 8.3 14.0 7.1 6.7 1.7 3.3 3 0 0 3 3 3 0 DDHD domain Ctr PF04145.15 CDJ41046.1 - 6.9 7.3 8.3 31 5.1 0.1 3.7 3 0 0 3 3 3 0 Ctr copper transporter family CTP_transf_1 PF01148.20 CDJ41048.1 - 0.00063 19.6 0.3 0.00082 19.2 0.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Nop53 PF07767.11 CDJ41050.1 - 0.013 14.9 10.3 0.016 14.6 10.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Caldesmon PF02029.15 CDJ41050.1 - 0.04 12.7 11.5 0.047 12.4 11.5 1.0 1 0 0 1 1 1 0 Caldesmon TCP PF03634.13 CDJ41050.1 - 0.29 11.7 16.5 0.35 11.4 16.5 1.0 1 0 0 1 1 1 0 TCP family transcription factor Roughex PF06020.11 CDJ41050.1 - 0.35 9.9 5.3 0.4 9.7 5.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein SprA-related PF12118.8 CDJ41050.1 - 0.44 9.6 22.0 0.53 9.4 22.0 1.1 1 0 0 1 1 1 0 SprA-related family PIP5K PF01504.18 CDJ41050.1 - 0.55 9.4 8.4 0.82 8.8 8.4 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase FAM199X PF15814.5 CDJ41050.1 - 0.63 9.0 16.8 0.71 8.9 16.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X DUF4407 PF14362.6 CDJ41050.1 - 0.74 9.1 5.9 0.71 9.2 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GET2 PF08690.10 CDJ41050.1 - 0.92 9.1 17.0 1 9.0 17.0 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 CDC45 PF02724.14 CDJ41050.1 - 1.3 7.2 12.4 1.5 7.0 12.4 1.0 1 0 0 1 1 1 0 CDC45-like protein eIF-3_zeta PF05091.12 CDJ41050.1 - 1.8 7.4 13.1 1.8 7.4 13.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EOS1 PF12326.8 CDJ41050.1 - 2.5 8.0 8.2 3.5 7.5 8.2 1.2 1 0 0 1 1 1 0 N-glycosylation protein Presenilin PF01080.17 CDJ41050.1 - 2.8 6.6 17.1 3.4 6.4 17.1 1.0 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ41050.1 - 4 7.3 25.3 5.6 6.9 25.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.6 CDJ41050.1 - 5 4.9 18.5 5 4.9 18.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med3 PF11593.8 CDJ41051.1 - 0.012 14.9 10.0 0.013 14.7 10.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Trp_oprn_chp PF09534.10 CDJ41051.1 - 0.015 15.1 1.5 0.018 14.8 1.5 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TFIIA PF03153.13 CDJ41051.1 - 0.018 15.0 9.4 0.019 15.0 9.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ41051.1 - 0.1 13.3 6.4 0.12 13.0 6.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region THOC2_N PF16134.5 CDJ41051.1 - 0.22 10.1 2.3 0.25 9.9 2.3 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Suf PF05843.14 CDJ41051.1 - 0.41 10.6 3.8 0.41 10.6 3.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ribosomal_60s PF00428.19 CDJ41051.1 - 0.46 11.1 6.0 0.77 10.4 6.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Presenilin PF01080.17 CDJ41051.1 - 0.53 9.0 2.2 0.53 9.0 2.2 1.0 1 0 0 1 1 1 0 Presenilin R_equi_Vir PF05526.11 CDJ41051.1 - 0.55 10.1 1.8 0.67 9.8 1.8 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Baculo_PP31 PF05311.11 CDJ41051.1 - 0.76 9.2 3.2 0.85 9.1 3.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SR-25 PF10500.9 CDJ41052.1 - 0.32 10.6 19.6 0.062 12.9 12.5 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SAP18 PF06487.12 CDJ41052.1 - 0.34 11.1 3.3 2.5 8.3 0.1 2.5 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) DNA_binding_2 PF13724.6 CDJ41052.1 - 8.7 6.8 6.2 48 4.4 1.4 2.9 2 0 0 2 2 2 0 DNA-binding domain Catalase PF00199.19 CDJ41053.1 - 7.7e-13 48.3 0.0 8.7e-13 48.1 0.0 1.0 1 0 0 1 1 1 1 Catalase DUF4094 PF13334.6 CDJ41054.1 - 0.0009 19.6 0.1 0.0013 19.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) SYS1 PF09801.9 CDJ41054.1 - 0.02 15.0 1.4 0.024 14.8 1.4 1.3 1 1 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network TALPID3 PF15324.6 CDJ41054.1 - 0.052 11.2 2.1 0.067 10.9 2.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target TMEM52 PF14979.6 CDJ41054.1 - 0.092 12.7 0.6 0.14 12.1 0.6 1.2 1 0 0 1 1 1 0 Transmembrane 52 Methyltransf_5 PF01795.19 CDJ41056.1 - 5.9e-25 88.4 1.1 2.6e-24 86.3 1.1 2.0 1 1 0 1 1 1 1 MraW methylase family Methyltransf_23 PF13489.6 CDJ41056.1 - 0.00086 19.2 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MRP PF09387.10 CDJ41056.1 - 0.032 14.2 1.0 0.032 14.2 1.0 1.9 2 1 1 3 3 3 0 Mitochondrial RNA binding protein MRP Pkinase PF00069.25 CDJ41057.1 - 4e-23 82.1 3.4 1.6e-15 57.2 0.2 2.8 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ41057.1 - 2.3e-08 33.6 5.2 2.4e-05 23.8 0.7 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Ribosomal_60s PF00428.19 CDJ41057.1 - 0.0011 19.5 7.7 0.033 14.8 5.5 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF908 PF06012.12 CDJ41057.1 - 0.0086 15.5 6.4 0.0096 15.4 6.4 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) Endostatin PF06482.11 CDJ41057.1 - 0.23 10.9 12.2 0.31 10.5 12.2 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin ALMT PF11744.8 CDJ41057.1 - 0.34 9.7 3.4 0.3 9.8 3.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MAP7 PF05672.11 CDJ41057.1 - 0.38 10.4 24.4 0.53 10.0 24.4 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Presenilin PF01080.17 CDJ41057.1 - 0.63 8.7 16.4 0.76 8.5 16.4 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ41057.1 - 0.7 9.9 8.5 0.97 9.4 8.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A SARAF PF06682.12 CDJ41057.1 - 0.93 9.1 18.2 1.7 8.2 18.2 1.5 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CIAPIN1 PF05093.13 CDJ41057.1 - 0.97 10.0 7.5 1.3 9.6 1.5 2.3 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis PAT1 PF09770.9 CDJ41057.1 - 0.99 7.6 32.2 1.2 7.3 32.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM70 PF14967.6 CDJ41057.1 - 2.4 7.5 9.6 3.6 7.0 9.6 1.2 1 0 0 1 1 1 0 FAM70 protein Pneumo_att_G PF05539.11 CDJ41057.1 - 3 7.4 11.3 4.7 6.7 11.3 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Gti1_Pac2 PF09729.9 CDJ41057.1 - 3.3 7.8 9.0 4.6 7.3 9.0 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 CDJ41057.1 - 4.3 6.3 11.8 5.1 6.0 11.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 CDJ41057.1 - 6.1 6.3 18.8 8.3 5.9 18.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sec62 PF03839.16 CDJ41057.1 - 6.8 6.1 8.2 9.4 5.7 8.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Membralin PF09746.9 CDJ41057.1 - 7.2 5.5 7.2 9.9 5.1 7.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF2828 PF11443.8 CDJ41057.1 - 8.7 4.3 12.1 12 3.9 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SR-25 PF10500.9 CDJ41059.1 - 0.035 13.7 30.7 0.03 13.9 9.4 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1180 PF06679.12 CDJ41060.1 - 0.32 11.4 4.9 0.41 11.0 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF3800 PF12686.7 CDJ41061.1 - 0.045 14.4 0.3 15 6.2 0.3 4.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Pex2_Pex12 PF04757.14 CDJ41062.1 - 1.6e-05 24.6 5.1 0.023 14.3 0.0 2.6 2 1 0 2 2 2 2 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 CDJ41062.1 - 0.00043 20.6 18.5 0.00096 19.4 18.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CDJ41062.1 - 0.00068 19.7 17.8 0.0033 17.6 17.9 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING SpoIIIAH PF12685.7 CDJ41062.1 - 0.00097 19.0 3.0 0.0025 17.7 0.3 2.2 2 0 0 2 2 2 1 SpoIIIAH-like protein DUF4228 PF14009.6 CDJ41062.1 - 0.0014 19.0 5.2 0.0054 17.1 0.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4228) Herpes_capsid PF06112.11 CDJ41062.1 - 0.012 15.7 9.2 0.012 15.7 9.2 3.1 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein DUF755 PF05501.11 CDJ41062.1 - 0.016 15.5 4.6 0.016 15.5 4.6 4.5 3 2 0 4 4 1 0 Domain of unknown function (DUF755) zf-RING_UBOX PF13445.6 CDJ41062.1 - 0.05 13.6 17.1 0.042 13.9 15.3 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ41062.1 - 0.076 12.9 19.6 0.16 11.9 19.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 CDJ41062.1 - 0.26 11.7 9.1 0.51 10.8 9.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CDJ41062.1 - 0.62 10.4 21.3 2 8.8 21.3 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain MAP17 PF15807.5 CDJ41062.1 - 0.74 10.1 0.0 0.74 10.1 0.0 2.6 2 1 0 2 2 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Ribosomal_60s PF00428.19 CDJ41062.1 - 0.98 10.0 6.5 8.1 7.1 2.4 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-RING_5 PF14634.6 CDJ41062.1 - 3 7.9 21.4 24 5.0 21.8 2.3 1 1 1 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ41062.1 - 8.5 6.3 20.0 34 4.4 20.0 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 WW PF00397.26 CDJ41063.1 - 1.1e-09 38.1 2.2 1.9e-09 37.4 2.2 1.4 1 0 0 1 1 1 1 WW domain DUF3328 PF11807.8 CDJ41063.1 - 0.085 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Wzz PF02706.15 CDJ41063.1 - 0.13 12.5 7.7 0.2 12.0 0.5 3.6 3 0 0 3 3 3 0 Chain length determinant protein Yip1 PF04893.17 CDJ41063.1 - 0.14 11.9 16.9 2.2 8.0 17.0 2.6 1 1 1 2 2 2 0 Yip1 domain BAF1_ABF1 PF04684.13 CDJ41063.1 - 0.17 10.9 5.0 0.09 11.8 1.1 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Las1 PF04031.13 CDJ41064.1 - 1.4e-35 122.7 3.2 1.4e-35 122.7 3.2 5.0 3 2 0 3 3 3 1 Las1-like DUF4079 PF13301.6 CDJ41064.1 - 8.8 6.5 10.3 0.3 11.2 0.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) TFIIA PF03153.13 CDJ41065.1 - 0.0035 17.4 4.8 0.0035 17.4 4.8 5.5 3 1 2 5 5 5 2 Transcription factor IIA, alpha/beta subunit PrmA PF06325.13 CDJ41065.1 - 0.014 14.8 0.1 0.014 14.8 0.1 3.7 4 1 1 5 5 5 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CDJ41065.1 - 0.14 12.9 0.0 0.71 10.6 0.0 2.4 1 0 0 1 1 1 0 Methyltransferase domain PhoLip_ATPase_C PF16212.5 CDJ41066.1 - 3.1e-52 177.8 18.9 3.1e-52 177.8 18.9 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDJ41066.1 - 1.5e-16 59.8 0.3 4.6e-16 58.3 0.3 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CDJ41066.1 - 4e-11 43.6 3.0 1.4e-06 28.8 0.5 3.9 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ41066.1 - 5e-07 29.7 0.0 3.7e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CDJ41066.1 - 4e-06 26.5 3.2 0.00015 21.3 0.0 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CDJ41066.1 - 0.035 13.8 0.1 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Sas10 PF09368.10 CDJ41068.1 - 1.6e-22 79.7 7.1 1.6e-22 79.7 7.1 2.5 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CDJ41068.1 - 1.2e-18 67.4 4.2 4.4e-18 65.7 2.7 2.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family YebO PF13974.6 CDJ41068.1 - 0.2 11.8 5.0 0.4 10.8 2.1 3.1 2 0 0 2 2 2 0 YebO-like protein GAT PF03127.14 CDJ41068.1 - 7.1 7.0 8.2 0.6 10.5 1.0 2.9 3 0 0 3 3 3 0 GAT domain RRM_1 PF00076.22 CDJ41070.1 - 6.4e-17 61.1 0.0 8.7e-17 60.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ41070.1 - 0.0044 17.1 0.0 0.026 14.6 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CDJ41070.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PseudoU_synth_2 PF00849.22 CDJ41071.1 - 7.3e-05 22.9 0.0 0.00025 21.2 0.0 2.0 2 0 0 2 2 2 1 RNA pseudouridylate synthase Herpes_UL43 PF05072.13 CDJ41073.1 - 0.069 12.2 0.2 0.083 12.0 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL43 protein PIRT PF15099.6 CDJ41074.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family C2 PF00168.30 CDJ41076.1 - 5.2e-10 39.5 0.0 9.4e-09 35.5 0.0 2.5 1 1 0 1 1 1 1 C2 domain Chorion_2 PF03964.15 CDJ41076.1 - 0.0037 18.1 1.2 0.0037 18.1 1.2 4.3 4 0 0 4 4 4 1 Chorion family 2 Transglut_core PF01841.19 CDJ41076.1 - 0.1 13.1 0.2 0.29 11.6 0.2 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily Ribosomal_S8 PF00410.19 CDJ41077.1 - 3.2e-21 75.6 0.0 3.7e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Mito_carr PF00153.27 CDJ41078.1 - 5.7e-24 83.9 0.4 9.4e-13 47.9 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein V-SNARE_C PF12352.8 CDJ41079.1 - 3.2e-11 43.3 1.3 2.7e-10 40.4 1.1 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 CDJ41079.1 - 1.6e-05 25.2 4.7 6.6e-05 23.2 0.3 2.8 3 1 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus EF-hand_6 PF13405.6 CDJ41080.1 - 1e-07 31.3 0.1 2.3e-07 30.2 0.1 1.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CDJ41080.1 - 1.2e-06 27.6 0.1 3.7e-06 26.1 0.1 1.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CDJ41080.1 - 4.9e-06 26.9 0.0 7.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair Milton PF12448.8 CDJ41080.1 - 0.036 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 Kinesin associated protein EF-hand_9 PF14658.6 CDJ41080.1 - 0.082 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain 7TM_GPCR_Srw PF10324.9 CDJ41080.1 - 0.097 11.9 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw EF-hand_8 PF13833.6 CDJ41081.1 - 3.8e-05 23.4 0.1 0.00013 21.8 0.1 1.8 1 1 0 1 1 1 1 EF-hand domain pair DUF3008 PF11450.8 CDJ41081.1 - 0.00034 20.7 0.1 0.00039 20.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknwon function (DUF3008) EF-hand_7 PF13499.6 CDJ41081.1 - 0.045 14.2 0.1 0.079 13.4 0.1 1.6 1 1 0 1 1 1 0 EF-hand domain pair LEM PF03020.15 CDJ41081.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 LEM domain AAA_lid_2 PF17863.1 CDJ41081.1 - 0.15 11.9 0.0 0.35 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA lid domain DEAD PF00270.29 CDJ41082.1 - 2e-41 141.6 0.0 3.7e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ41082.1 - 4.9e-27 94.5 0.0 1.2e-26 93.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain mIF3 PF14877.6 CDJ41082.1 - 0.08 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Cyt-b5 PF00173.28 CDJ41083.1 - 1.8e-22 79.2 0.0 2.4e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DnaJ PF00226.31 CDJ41084.1 - 3.9e-15 55.7 0.0 1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Phage_prot_Gp6 PF05133.14 CDJ41084.1 - 0.098 11.7 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like GPDPase_memb PF10110.9 CDJ41086.1 - 0.049 12.4 0.5 0.076 11.8 0.5 1.1 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Fcf2 PF08698.11 CDJ41088.1 - 4.3e-10 39.9 0.0 1.1e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing MMR_HSR1 PF01926.23 CDJ41089.1 - 1.3e-44 151.0 0.0 1.1e-22 80.3 0.0 2.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ41089.1 - 5.1e-21 74.8 0.0 1.7e-11 43.9 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDJ41089.1 - 1.1e-18 67.5 1.1 3.5e-07 30.0 0.4 4.5 4 1 0 4 4 4 3 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CDJ41089.1 - 8.5e-11 41.6 0.0 4.1e-05 23.0 0.0 2.5 3 0 0 3 3 3 2 AIG1 family KH_dom-like PF14714.6 CDJ41089.1 - 7.7e-10 39.0 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Roc PF08477.13 CDJ41089.1 - 1.2e-08 35.2 0.0 0.013 15.7 0.0 4.2 2 2 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ41089.1 - 3.8e-06 26.6 0.0 0.1 12.2 0.0 3.8 2 2 0 2 2 2 2 Ras family RsgA_GTPase PF03193.16 CDJ41089.1 - 1.6e-05 24.9 0.0 2.4 8.0 0.0 4.2 4 0 0 4 4 4 1 RsgA GTPase Dynamin_N PF00350.23 CDJ41089.1 - 1.8e-05 24.9 0.0 0.16 12.0 0.0 3.3 4 0 0 4 4 4 2 Dynamin family MeaB PF03308.16 CDJ41089.1 - 8e-05 21.7 0.3 1.1 8.2 0.1 4.0 3 1 1 4 4 4 2 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CDJ41089.1 - 0.00021 21.0 0.2 0.1 12.2 0.1 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 CDJ41089.1 - 0.0035 16.8 0.0 19 4.6 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Arf PF00025.21 CDJ41089.1 - 0.013 14.9 0.0 1.4 8.4 0.0 3.6 4 1 0 4 4 4 0 ADP-ribosylation factor family MCM PF00493.23 CDJ41089.1 - 0.018 14.2 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain ABC_tran PF00005.27 CDJ41089.1 - 0.17 12.4 0.0 5.2 7.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter TPP_enzyme_M PF00205.22 CDJ41089.1 - 0.18 11.6 0.3 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Glyco_hydro_3_C PF01915.22 CDJ41089.1 - 0.21 11.5 0.3 0.64 9.9 0.1 1.9 2 1 0 2 2 1 0 Glycosyl hydrolase family 3 C-terminal domain Nup84_Nup100 PF04121.13 CDJ41090.1 - 9.1e-08 30.7 2.6 0.0073 14.5 0.1 3.6 4 0 0 4 4 4 3 Nuclear pore protein 84 / 107 FUSC_2 PF13515.6 CDJ41091.1 - 6.7e-07 29.5 10.1 6.7e-07 29.5 10.1 3.1 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ANAPC4_WD40 PF12894.7 CDJ41092.1 - 0.00013 22.2 0.0 0.003 17.8 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ41092.1 - 0.0013 19.6 1.7 12 6.9 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Mcl1_mid PF12341.8 CDJ41092.1 - 0.0097 15.3 0.3 14 4.9 0.0 3.0 1 1 2 3 3 3 2 Minichromosome loss protein, Mcl1, middle region RNase_PH PF01138.21 CDJ41093.1 - 1.8e-15 57.6 3.6 8e-15 55.5 3.6 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 SCPU PF05229.15 CDJ41093.1 - 0.043 14.2 0.7 0.083 13.3 0.7 1.4 1 0 0 1 1 1 0 Spore Coat Protein U domain RNA_pol_Rpb2_6 PF00562.28 CDJ41094.1 - 9.2e-124 413.4 0.0 1.2e-123 413.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CDJ41094.1 - 9.3e-60 201.6 0.0 1.3e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CDJ41094.1 - 7.1e-48 162.8 0.0 1.2e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CDJ41094.1 - 3.6e-33 113.8 0.5 8e-33 112.7 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 CDJ41094.1 - 3.4e-26 91.2 0.0 7.6e-26 90.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 CDJ41094.1 - 1.7e-20 73.0 0.1 3.4e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 CDJ41094.1 - 1.8e-16 60.5 1.8 4.8e-16 59.1 1.8 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 TBP PF00352.21 CDJ41095.1 - 2.9e-12 46.4 0.0 1.4e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) CD34_antigen PF06365.12 CDJ41097.1 - 0.048 13.2 0.1 0.073 12.6 0.1 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family SLBP_RNA_bind PF15247.6 CDJ41098.1 - 2.1e-23 82.2 1.3 4e-23 81.3 1.3 1.5 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain RT_RNaseH PF17917.1 CDJ41099.1 - 8.2e-28 96.8 0.0 1.2e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ41099.1 - 1.6e-27 95.5 0.0 2.3e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RNase_H PF00075.24 CDJ41099.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 RNase H RVT_3 PF13456.6 CDJ41099.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like Retrotrans_gag PF03732.17 CDJ41100.1 - 0.0011 19.2 0.0 0.013 15.8 0.0 2.5 3 0 0 3 3 3 1 Retrotransposon gag protein Kinesin PF00225.23 CDJ41101.1 - 1.6e-93 313.2 0.3 3.4e-93 312.2 0.3 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ41101.1 - 5.2e-19 68.7 0.3 3.6e-16 59.4 0.0 2.9 1 1 1 2 2 2 2 Microtubule binding tRNA-synt_2b PF00587.25 CDJ41102.1 - 1.1e-29 103.7 0.0 1.7e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Vps51 PF08700.11 CDJ41104.1 - 3.9e-05 23.7 0.0 8.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 RNA_GG_bind PF10258.9 CDJ41106.1 - 1.9e-24 85.5 0.1 3.4e-24 84.7 0.1 1.3 1 0 0 1 1 1 1 PHAX RNA-binding domain Ribosomal_L13e PF01294.18 CDJ41106.1 - 0.082 12.8 1.8 0.13 12.1 1.8 1.2 1 0 0 1 1 1 0 Ribosomal protein L13e SUR7 PF06687.12 CDJ41108.1 - 2 8.0 5.6 1.5 8.4 2.5 2.1 2 1 0 2 2 2 0 SUR7/PalI family EI24 PF07264.11 CDJ41108.1 - 4.9 7.4 13.7 13 6.0 13.7 1.6 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) SIS PF01380.22 CDJ41109.1 - 2.1e-36 124.7 0.3 9.5e-19 67.5 0.0 2.6 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 CDJ41109.1 - 4e-20 72.4 0.0 8.2e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CDJ41109.1 - 5.1e-16 58.7 0.0 9.3e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CDJ41109.1 - 1.7e-05 23.9 0.1 3.4e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II LRR_4 PF12799.7 CDJ41110.1 - 3.2e-06 27.4 3.8 0.005 17.2 0.1 3.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ41110.1 - 3e-05 23.7 2.1 0.046 13.8 0.1 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_9 PF14580.6 CDJ41110.1 - 0.00039 20.0 0.3 0.00068 19.2 0.3 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CDJ41110.1 - 0.00043 20.0 1.9 0.22 11.3 0.2 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 CDJ41110.1 - 0.0039 17.5 1.1 20 6.2 0.1 4.5 3 1 0 3 3 3 1 Leucine Rich Repeat Dscam_C PF12355.8 CDJ41110.1 - 1.6 9.7 5.3 1.1 10.3 2.8 2.0 1 1 1 2 2 2 0 Down syndrome cell adhesion molecule C terminal ABC1 PF03109.16 CDJ41112.1 - 9.1e-15 54.9 0.0 1.4e-10 41.3 0.0 2.5 2 0 0 2 2 2 2 ABC1 family K-box PF01486.17 CDJ41115.1 - 0.002 18.2 0.5 0.002 18.2 0.5 3.1 3 1 0 3 3 3 1 K-box region AIP3 PF03915.13 CDJ41115.1 - 0.017 14.2 1.9 0.18 10.9 1.9 2.1 1 1 0 1 1 1 0 Actin interacting protein 3 CheZ PF04344.13 CDJ41115.1 - 0.024 14.6 4.2 0.21 11.5 1.1 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ SRA1 PF07304.11 CDJ41115.1 - 0.033 14.0 1.1 1.4 8.7 0.4 2.6 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) DUF1192 PF06698.11 CDJ41115.1 - 0.041 13.9 0.9 0.12 12.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Cep57_MT_bd PF06657.13 CDJ41115.1 - 0.065 13.7 5.8 0.48 10.9 0.4 3.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Phage_lysozyme2 PF18013.1 CDJ41115.1 - 0.13 12.2 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 Phage tail lysozyme CCDC144C PF14915.6 CDJ41115.1 - 0.16 11.1 7.5 0.13 11.3 2.0 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Surfac_D-trimer PF09006.11 CDJ41115.1 - 0.16 11.9 1.4 1.3 9.0 0.0 2.9 3 1 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation M16C_assoc PF08367.11 CDJ41116.1 - 2.2e-31 108.9 0.0 4.8e-31 107.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CDJ41116.1 - 2.1e-07 31.2 1.8 2.3e-06 27.8 0.0 3.1 3 1 0 3 3 3 1 Peptidase M16 inactive domain DUF4240 PF14024.6 CDJ41116.1 - 0.23 11.7 2.4 0.58 10.3 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) SURF6 PF04935.12 CDJ41118.1 - 0.00032 20.6 32.8 0.00032 20.6 32.8 2.2 1 1 1 2 2 2 1 Surfeit locus protein 6 GREB1 PF15782.5 CDJ41118.1 - 6.5 3.7 27.8 8.2 3.4 27.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ebp2 PF05890.12 CDJ41119.1 - 1.8e-19 70.4 9.3 2.4e-19 70.0 9.3 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 GET2 PF08690.10 CDJ41119.1 - 0.81 9.3 11.2 1.7 8.3 3.7 2.1 1 1 1 2 2 2 0 GET complex subunit GET2 DUF2722 PF10846.8 CDJ41120.1 - 0.0088 15.0 4.0 0.01 14.8 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) GREB1 PF15782.5 CDJ41120.1 - 0.76 6.8 3.8 0.83 6.7 3.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DGF-1_C PF11040.8 CDJ41120.1 - 1.2 9.2 4.6 1.2 9.1 3.5 1.7 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Spt20 PF12090.8 CDJ41120.1 - 1.7 8.2 9.0 2.2 7.8 9.0 1.2 1 0 0 1 1 1 0 Spt20 family CDK2AP PF09806.9 CDJ41120.1 - 2.2 8.3 6.3 2.6 8.0 6.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SUIM_assoc PF16619.5 CDJ41122.1 - 0.059 13.4 15.3 0.32 11.1 3.4 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2380 PF09533.10 CDJ41122.1 - 6.8 6.3 11.5 0.29 10.7 2.7 2.4 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) Spt20 PF12090.8 CDJ41122.1 - 8.3 5.9 16.4 0.07 12.7 0.7 2.3 2 1 0 2 2 2 0 Spt20 family PEX11 PF05648.14 CDJ41123.1 - 4.9e-10 39.2 0.1 5.1e-10 39.2 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) CDK2AP PF09806.9 CDJ41124.1 - 2.1 8.4 13.1 2.2 8.3 13.1 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1635 PF07795.11 CDJ41124.1 - 4.3 7.1 13.2 4.8 7.0 13.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) FAM60A PF15396.6 CDJ41124.1 - 6.2 6.8 10.3 6.3 6.7 10.3 1.0 1 0 0 1 1 1 0 Protein Family FAM60A WAPL PF07814.13 CDJ41128.1 - 0.03 13.1 0.1 0.045 12.5 0.1 1.2 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin FTA4 PF13093.6 CDJ41128.1 - 0.045 13.6 2.2 0.077 12.9 2.2 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 LIME1 PF15332.6 CDJ41131.1 - 0.11 12.0 1.7 0.12 11.9 1.7 1.0 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 BAF PF02961.14 CDJ41131.1 - 0.13 12.7 0.0 0.41 11.1 0.0 1.7 2 0 0 2 2 2 0 Barrier to autointegration factor FtsL PF04999.13 CDJ41132.1 - 0.087 12.8 1.0 2.2 8.3 0.0 2.7 2 0 0 2 2 2 0 Cell division protein FtsL CRAL_TRIO PF00650.20 CDJ41133.1 - 4.1e-26 91.6 0.0 5.4e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ41133.1 - 0.055 13.6 0.0 0.082 13.1 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Lant_dehydr_C PF14028.6 CDJ41133.1 - 0.41 10.2 9.1 0.73 9.3 9.1 1.5 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Gly-zipper_OmpA PF13436.6 CDJ41134.1 - 0.067 13.0 1.4 0.067 13.0 1.4 3.5 3 1 0 3 3 3 0 Glycine-zipper domain Bacteriocin_IIc PF10439.9 CDJ41134.1 - 1.7 8.9 21.3 0.76 9.9 2.9 3.5 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.6 CDJ41134.1 - 6.8 6.5 11.3 0.99 9.2 1.6 2.6 2 0 0 2 2 2 0 YMGG-like Gly-zipper Pyr_redox_2 PF07992.14 CDJ41135.1 - 3.7e-34 118.3 0.1 1.4e-32 113.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ41135.1 - 8.6e-20 71.0 0.0 1.6e-17 63.8 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDJ41135.1 - 4.1e-13 49.7 0.0 4.1e-13 49.7 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 CDJ41135.1 - 0.00018 20.9 2.4 0.0033 16.8 0.0 3.0 3 1 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CDJ41135.1 - 0.00028 20.3 0.9 0.55 9.5 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CDJ41135.1 - 0.0014 17.7 4.3 0.0023 17.1 0.6 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 CDJ41135.1 - 0.0017 18.3 1.8 0.026 14.4 0.0 2.7 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CDJ41135.1 - 0.022 14.3 0.1 0.022 14.3 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 CDJ41135.1 - 0.094 11.8 4.7 0.03 13.4 1.4 2.0 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.6 CDJ41135.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CDJ41135.1 - 1.6 9.0 7.9 0.24 11.7 0.3 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CDJ41135.1 - 4 6.0 4.8 2 7.1 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein DUF1356 PF07092.12 CDJ41136.1 - 0.14 11.4 0.6 0.21 10.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) Zip PF02535.22 CDJ41137.1 - 7.8e-22 77.9 20.9 4.9e-20 72.0 20.9 2.7 1 1 0 1 1 1 1 ZIP Zinc transporter BrkDBD PF09607.10 CDJ41138.1 - 0.16 11.7 0.3 0.16 11.7 0.3 2.3 2 0 0 2 2 2 0 Brinker DNA-binding domain SR-25 PF10500.9 CDJ41139.1 - 1.2 8.7 38.6 2 8.0 33.1 2.9 2 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.11 CDJ41139.1 - 2.7 7.8 17.4 2.4 8.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DUF4683 PF15735.5 CDJ41139.1 - 3.4 7.2 16.7 7.1 6.1 16.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) Sporozoite_P67 PF05642.11 CDJ41139.1 - 4.1 5.4 18.9 7.2 4.6 18.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2722 PF10846.8 CDJ41140.1 - 0.014 14.4 3.7 0.014 14.3 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC45 PF02724.14 CDJ41141.1 - 0.19 10.0 14.0 0.36 9.1 14.0 1.4 1 0 0 1 1 1 0 CDC45-like protein V_ATPase_I PF01496.19 CDJ41141.1 - 3.5 5.4 6.1 4.8 5.0 6.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rxt3 PF08642.10 CDJ41141.1 - 9.6 7.0 7.1 1e+02 3.7 7.1 2.5 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 NTP_transf_6 PF06042.11 CDJ41142.1 - 0.061 13.2 3.4 0.095 12.6 3.4 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase PTPRCAP PF15713.5 CDJ41142.1 - 0.4 11.0 26.4 0.47 10.7 15.3 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Apt1 PF10351.9 CDJ41142.1 - 6.6 5.5 15.8 0.81 8.5 6.3 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain Neur_chan_memb PF02932.16 CDJ41142.1 - 7.8 6.5 8.6 4 7.4 1.3 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.25 CDJ41143.1 - 2e-47 161.8 0.0 2.3e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ41143.1 - 1.9e-24 86.3 0.0 2.4e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ41143.1 - 3.8e-05 23.1 0.0 5.5e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ41143.1 - 0.018 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CDJ41143.1 - 0.052 12.9 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DLIC PF05783.11 CDJ41144.1 - 0.39 9.5 2.3 0.66 8.7 2.3 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Ribosomal_60s PF00428.19 CDJ41144.1 - 1.3 9.7 26.3 0.11 13.1 1.9 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Ribosom_S12_S23 PF00164.25 CDJ41145.1 - 1.4e-51 172.9 0.3 1.9e-51 172.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_15 PF09445.10 CDJ41145.1 - 0.03 13.9 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase EMP24_GP25L PF01105.24 CDJ41146.1 - 2.6e-25 89.4 0.0 4.2e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD XTBD PF11952.8 CDJ41147.1 - 1e-06 28.4 0.8 1.8e-06 27.6 0.8 1.4 1 0 0 1 1 1 1 XRN-Two Binding Domain, XTBD SAP130_C PF16014.5 CDJ41147.1 - 2.2 7.3 16.3 3 6.9 16.3 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Collagen PF01391.18 CDJ41148.1 - 3.1e-06 26.8 21.1 3.1e-06 26.8 21.1 4.0 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Na_trans_assoc PF06512.13 CDJ41149.1 - 0.24 11.7 14.8 0.27 11.5 10.8 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated WBP-1 PF11669.8 CDJ41150.1 - 0.0022 18.6 2.3 0.0027 18.3 2.3 1.1 1 0 0 1 1 1 1 WW domain-binding protein 1 DNA_pol3_a_NII PF11490.8 CDJ41150.1 - 0.0055 16.6 2.6 0.0067 16.3 2.6 1.1 1 0 0 1 1 1 1 DNA polymerase III polC-type N-terminus II RskA PF10099.9 CDJ41150.1 - 0.049 13.9 1.4 0.059 13.7 1.4 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA MscS_TM PF12794.7 CDJ41150.1 - 0.077 11.8 1.4 0.098 11.5 1.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4834 PF16118.5 CDJ41150.1 - 0.1 13.6 0.6 0.13 13.2 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Activator_LAG-3 PF11498.8 CDJ41150.1 - 0.21 10.5 11.5 0.21 10.5 11.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CheY-binding PF09078.11 CDJ41152.1 - 0.19 11.9 2.4 0.89 9.7 0.1 2.8 3 0 0 3 3 3 0 CheY binding PPIP5K2_N PF18086.1 CDJ41152.1 - 0.24 11.6 0.0 0.63 10.2 0.0 1.7 1 0 0 1 1 1 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Prefoldin_2 PF01920.20 CDJ41153.1 - 0.0027 17.6 0.0 0.0032 17.4 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit RbpA PF13397.6 CDJ41154.1 - 0.023 15.3 1.9 0.068 13.8 1.9 1.8 1 0 0 1 1 1 0 RNA polymerase-binding protein Takusan PF04822.13 CDJ41155.1 - 0.017 15.0 0.6 0.048 13.5 0.6 1.8 1 0 0 1 1 1 0 Takusan CxxCxxCC PF03692.15 CDJ41155.1 - 0.14 12.9 0.2 0.14 12.9 0.2 2.3 3 0 0 3 3 3 0 Putative zinc- or iron-chelating domain US6 PF17616.2 CDJ41156.1 - 0.29 11.1 1.3 0.42 10.5 1.3 1.1 1 0 0 1 1 1 0 Viral unique short region 6 Adeno_E3_CR2 PF02439.15 CDJ41156.1 - 1.4 8.7 3.9 14 5.6 0.0 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 IRK_C PF17655.1 CDJ41157.1 - 5.1e-06 26.2 0.0 8.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 CDJ41157.1 - 0.016 15.1 0.8 0.033 14.1 0.8 1.5 1 0 0 1 1 1 0 Ion channel IRK PF01007.20 CDJ41157.1 - 0.04 13.7 0.1 0.087 12.6 0.1 1.6 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain GAS PF13851.6 CDJ41161.1 - 0.0057 16.0 9.9 0.0086 15.4 9.8 1.3 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding NCD2 PF04905.13 CDJ41161.1 - 0.018 15.0 0.8 0.022 14.7 0.8 1.1 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) Ead_Ea22 PF13935.6 CDJ41161.1 - 0.032 14.9 1.7 0.045 14.4 1.7 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein IL11 PF07400.11 CDJ41161.1 - 0.056 13.1 0.2 0.06 13.0 0.2 1.1 1 0 0 1 1 1 0 Interleukin 11 DUF4238 PF14022.6 CDJ41161.1 - 0.065 12.7 1.1 0.07 12.6 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) DUF1151 PF06625.11 CDJ41161.1 - 0.066 13.2 5.3 0.081 12.9 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) G10 PF01125.17 CDJ41161.1 - 0.075 12.8 1.9 0.095 12.5 1.8 1.4 1 1 0 1 1 1 0 G10 protein FAM76 PF16046.5 CDJ41161.1 - 0.13 11.6 6.9 0.15 11.4 6.9 1.0 1 0 0 1 1 1 0 FAM76 protein YabA PF06156.13 CDJ41161.1 - 0.36 11.5 5.5 1.6 9.4 5.5 1.9 1 1 0 1 1 1 0 Initiation control protein YabA pRN1_helical PF13010.6 CDJ41161.1 - 0.5 10.3 6.6 0.16 11.9 4.1 1.4 2 0 0 2 2 2 0 Primase helical domain BST2 PF16716.5 CDJ41161.1 - 2 9.0 8.3 4.3 8.0 1.5 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 CCDC-167 PF15188.6 CDJ41161.1 - 2.3 8.6 7.2 5 7.5 2.4 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Csm1_N PF18504.1 CDJ41161.1 - 2.9 8.3 8.6 2.2 8.7 5.7 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain IFP_35_N PF07334.13 CDJ41161.1 - 4 7.6 13.1 4.6 7.4 0.8 3.0 1 1 2 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus KASH_CCD PF14662.6 CDJ41162.1 - 0.032 14.1 15.4 0.021 14.7 13.6 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 CDJ41162.1 - 0.11 12.6 12.9 0.15 12.2 12.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PLAC9 PF15205.6 CDJ41162.1 - 0.17 12.3 2.1 0.24 11.8 0.3 2.1 2 0 0 2 2 2 0 Placenta-specific protein 9 APG6_N PF17675.1 CDJ41162.1 - 1.1 9.8 21.0 6.7 7.2 21.1 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4790 PF16037.5 CDJ41162.1 - 1.4 9.4 5.1 3.5 8.1 0.6 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4790) EzrA PF06160.12 CDJ41163.1 - 0.0039 15.4 30.8 0.0049 15.1 30.8 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Spc7 PF08317.11 CDJ41163.1 - 1.7 7.4 44.9 0.27 10.1 30.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 CDJ41163.1 - 2 7.7 44.0 14 5.0 21.8 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 CDJ41163.1 - 2 8.8 39.1 5.3 7.5 12.4 2.3 1 1 1 2 2 2 0 Fez1 Hemagglutinin PF00509.18 CDJ41163.1 - 2.7 6.3 6.8 1.7 6.9 5.2 1.5 1 1 1 2 2 2 0 Haemagglutinin APG6_N PF17675.1 CDJ41163.1 - 2.9 8.4 54.1 0.9 10.1 23.6 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region Occludin_ELL PF07303.13 CDJ41163.1 - 4.1 8.2 24.7 0.35 11.6 7.1 3.1 1 1 2 3 3 3 0 Occludin homology domain Leu_zip PF15294.6 CDJ41163.1 - 4.6 6.7 32.0 5.3 6.5 30.8 1.6 1 1 1 2 2 2 0 Leucine zipper ADIP PF11559.8 CDJ41163.1 - 5.2 7.2 47.5 0.31 11.1 21.1 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 CDJ41163.1 - 5.7 7.1 47.8 3 8.0 28.9 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DHR10 PF18595.1 CDJ41163.1 - 5.8 7.0 56.0 0.042 13.9 22.9 3.8 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain DUF1664 PF07889.12 CDJ41163.1 - 6.1 6.9 24.8 6.9 6.7 2.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Rrn6 PF10214.9 CDJ41163.1 - 6.3 5.2 23.4 8 4.8 23.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor IFT57 PF10498.9 CDJ41163.1 - 8.7 5.2 33.5 17 4.2 33.5 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 SOBP PF15279.6 CDJ41163.1 - 9.8 6.7 9.9 13 6.3 9.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CARD PF00619.21 CDJ41164.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Caspase recruitment domain RRM_1 PF00076.22 CDJ41165.1 - 1.8e-28 98.2 0.0 2.6e-17 62.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ41165.1 - 1.4e-05 25.1 0.1 7e-05 22.9 0.1 2.2 2 1 0 2 2 2 1 RNA recognition motif Dynein_C PF18199.1 CDJ41166.1 - 7.7e-11 41.8 0.3 8e-11 41.7 0.3 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain MT PF12777.7 CDJ41167.1 - 8.6e-56 189.4 2.7 1.4e-55 188.7 2.7 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 CDJ41167.1 - 2.5e-51 174.5 0.2 1.2e-50 172.3 0.0 2.4 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDJ41167.1 - 1.6e-46 158.2 0.0 1.6e-46 158.2 0.0 2.5 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDJ41167.1 - 2.3e-28 98.9 0.0 3.1e-17 62.7 0.0 3.8 4 0 0 4 4 4 3 P-loop containing dynein motor region AAA_6 PF12774.7 CDJ41167.1 - 4.9e-23 81.6 1.7 3.2e-21 75.7 0.1 3.1 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_AAA_lid PF17852.1 CDJ41167.1 - 4.1e-16 59.2 0.0 1.1e-15 57.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ41167.1 - 1.3e-06 28.5 0.1 4.7e-05 23.5 0.0 3.3 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CDJ41167.1 - 0.00053 20.0 1.2 0.44 10.6 0.0 4.3 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CDJ41167.1 - 0.0052 16.2 3.0 0.56 9.5 0.1 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 CDJ41167.1 - 0.013 15.7 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA+ lid domain PRK PF00485.18 CDJ41167.1 - 0.13 12.0 0.9 0.75 9.5 0.2 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TssO PF17561.2 CDJ41167.1 - 0.7 10.0 3.4 1.2 9.2 0.3 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF4795 PF16043.5 CDJ41167.1 - 1.5 8.4 12.8 0.16 11.5 1.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Spc7 PF08317.11 CDJ41167.1 - 2.2 7.1 24.6 4.2 6.2 10.0 2.7 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_22 PF13401.6 CDJ41167.1 - 3.6 7.9 11.3 4.2 7.6 0.1 4.6 4 1 1 5 5 4 0 AAA domain DUF4407 PF14362.6 CDJ41167.1 - 4 6.7 23.9 0.0084 15.5 5.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) AAA_23 PF13476.6 CDJ41167.1 - 4.3 7.8 15.6 15 6.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_6 PF12774.7 CDJ41168.1 - 9.2e-91 304.2 0.0 1.5e-90 303.5 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ41168.1 - 3.2e-82 276.8 3.5 3.2e-82 276.8 3.5 2.6 2 1 1 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 CDJ41168.1 - 0.00036 20.5 0.0 0.0069 16.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) SNAP PF14938.6 CDJ41168.1 - 0.0045 16.5 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF4510 PF14971.6 CDJ41168.1 - 0.0088 16.4 1.4 0.0088 16.4 1.4 4.4 4 1 0 4 4 4 1 Domain of unknown function (DUF4510) eIF3m_C_helix PF18005.1 CDJ41168.1 - 0.02 14.6 3.4 0.24 11.1 0.4 2.9 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix AAA PF00004.29 CDJ41168.1 - 0.033 14.6 0.0 0.13 12.7 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ExbD PF02472.16 CDJ41168.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR HsbA PF12296.8 CDJ41168.1 - 0.24 11.8 3.1 1.6 9.2 0.7 3.6 5 0 0 5 5 4 0 Hydrophobic surface binding protein A T7SS_ESX_EspC PF10824.8 CDJ41168.1 - 1.2 9.6 8.4 21 5.7 1.8 3.6 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm THOC7 PF05615.13 CDJ41168.1 - 2.6 8.4 8.0 0.74 10.1 1.0 3.4 2 0 0 2 2 2 0 Tho complex subunit 7 Sec34 PF04136.15 CDJ41168.1 - 3.5 7.5 6.7 2.4 8.0 0.3 3.9 4 1 0 4 4 4 0 Sec34-like family Baculo_PEP_C PF04513.12 CDJ41168.1 - 6.8 6.7 7.8 28 4.7 0.1 4.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus PikAIV_N PF18605.1 CDJ41168.1 - 7.6 6.2 10.1 0.048 13.3 0.6 2.5 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain NurA PF09376.10 CDJ41171.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 NurA domain DUF4148 PF13663.6 CDJ41171.1 - 2 8.7 13.3 0.22 11.7 5.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Kin17_mid PF10357.9 CDJ41174.1 - 1.5e-42 144.5 3.5 3.2e-42 143.4 3.5 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 CDJ41174.1 - 9.7e-19 67.2 1.0 2.8e-18 65.8 1.0 1.8 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 CDJ41174.1 - 0.0069 16.7 4.0 0.018 15.4 4.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type NdhS PF11623.8 CDJ41174.1 - 0.18 11.5 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H dehydrogenase subunit S zf-C2H2_jaz PF12171.8 CDJ41174.1 - 0.32 11.3 7.3 0.13 12.6 4.2 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rick_17kDa_Anti PF05433.15 CDJ41176.1 - 0.1 12.5 0.5 0.21 11.5 0.5 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain Clat_adaptor_s PF01217.20 CDJ41177.1 - 1.1e-09 38.4 0.0 2.1e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Hydrolase_4 PF12146.8 CDJ41178.1 - 7.7e-22 77.7 0.0 3.2e-21 75.7 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF726 PF05277.12 CDJ41178.1 - 0.019 13.9 0.1 0.019 13.9 0.1 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.20 CDJ41178.1 - 0.051 13.2 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2457 PF10446.9 CDJ41179.1 - 0.074 12.2 21.7 0.2 10.8 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TFIIA PF03153.13 CDJ41179.1 - 0.32 11.0 30.5 0.42 10.5 30.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 CDJ41179.1 - 0.78 8.9 3.7 0.95 8.6 3.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 CDJ41179.1 - 2 6.6 17.7 3.1 6.0 17.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Membralin PF09746.9 CDJ41179.1 - 2.7 6.9 4.0 4 6.4 4.0 1.3 1 0 0 1 1 1 0 Tumour-associated protein GAGA_bind PF06217.12 CDJ41179.1 - 5.9 7.1 13.7 8.4 6.6 13.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CSRNP_N PF16019.5 CDJ41179.1 - 6.2 6.7 15.1 14 5.5 15.1 1.6 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Peptidase_S64 PF08192.11 CDJ41179.1 - 9 4.6 10.4 14 4.0 10.4 1.3 1 0 0 1 1 1 0 Peptidase family S64 SUIM_assoc PF16619.5 CDJ41180.1 - 5.9 7.0 16.0 5.7 7.1 2.9 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 CCDC-167 PF15188.6 CDJ41181.1 - 0.12 12.8 0.1 0.34 11.3 0.1 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 PHM7_cyt PF14703.6 CDJ41181.1 - 0.28 11.4 1.3 0.39 10.9 0.1 1.8 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Presenilin PF01080.17 CDJ41181.1 - 3.3 6.4 14.2 4.6 5.9 6.8 2.2 2 0 0 2 2 2 0 Presenilin Iso_dh PF00180.20 CDJ41182.1 - 2.1e-22 79.8 0.0 2.6e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.20 CDJ41183.1 - 2.5e-42 145.3 0.0 2.8e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phosphorylase PF00343.20 CDJ41184.1 - 5.6e-301 1000.1 0.0 6.9e-301 999.8 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase EGF_CA PF07645.15 CDJ41185.1 - 1.5e-211 684.5 545.7 1.5e-11 44.3 12.0 34.4 32 2 1 33 33 33 27 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ41185.1 - 2.7e-138 449.8 553.6 2.8e-10 40.2 16.3 33.7 34 0 0 34 34 34 29 EGF domain cEGF PF12662.7 CDJ41185.1 - 4.2e-134 435.8 309.2 9.2e-09 35.1 4.3 32.3 31 0 0 31 31 31 28 Complement Clr-like EGF-like EGF PF00008.27 CDJ41185.1 - 1.4e-72 239.5 413.7 0.00017 21.9 5.5 32.3 30 0 0 30 30 30 29 EGF-like domain hEGF PF12661.7 CDJ41185.1 - 1.1e-65 216.2 324.6 0.00015 22.2 2.4 32.0 29 0 0 29 29 29 26 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CDJ41185.1 - 1.8e-53 178.2 396.2 4.1e-07 29.9 8.6 32.9 33 0 0 33 33 33 26 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CDJ41185.1 - 3.1e-26 91.4 424.7 8.4e-05 22.8 8.3 31.8 31 2 2 33 33 33 25 Pvs28 EGF domain FXa_inhibition PF14670.6 CDJ41185.1 - 6.8e-25 87.1 481.0 0.00019 21.6 9.6 32.3 27 4 4 31 31 31 23 Coagulation Factor Xa inhibitory site HTH_20 PF12840.7 CDJ41185.1 - 2.6 8.2 4.2 62 3.8 0.0 4.6 6 0 0 6 6 6 0 Helix-turn-helix domain C2 PF00168.30 CDJ41187.1 - 3.1e-36 123.8 0.0 2.3e-13 50.3 0.0 4.9 5 0 0 5 5 5 4 C2 domain Ferlin_C PF16165.5 CDJ41187.1 - 0.015 15.3 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Ferlin C-terminus SF3b1 PF08920.10 CDJ41188.1 - 2.7e-26 92.4 21.0 6.7e-24 84.7 5.3 3.7 1 1 2 3 3 3 2 Splicing factor 3B subunit 1 HEAT PF02985.22 CDJ41188.1 - 5.1e-08 32.5 7.0 1.2 9.5 0.1 8.0 8 0 0 8 8 8 2 HEAT repeat UME PF08064.13 CDJ41188.1 - 8e-06 25.7 0.9 5.6 6.9 0.0 5.3 5 1 0 5 5 5 2 UME (NUC010) domain Adaptin_N PF01602.20 CDJ41188.1 - 5.8e-05 21.8 0.4 0.074 11.6 0.0 3.6 3 1 1 4 4 4 2 Adaptin N terminal region HEAT_EZ PF13513.6 CDJ41188.1 - 9.1e-05 22.9 10.5 0.27 11.8 0.0 6.2 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 CDJ41188.1 - 0.0015 18.8 19.4 0.18 12.2 0.1 7.2 5 2 4 9 9 9 3 HEAT repeats Arm PF00514.23 CDJ41188.1 - 0.017 15.2 1.2 68 3.7 0.0 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat NUC173 PF08161.12 CDJ41188.1 - 0.018 14.7 0.0 3.3 7.3 0.0 3.9 3 1 1 4 4 4 0 NUC173 domain CLASP_N PF12348.8 CDJ41188.1 - 0.022 14.4 0.1 1 8.8 0.0 2.6 2 0 0 2 2 2 0 CLASP N terminal Bep_C_terminal PF17841.1 CDJ41188.1 - 0.027 14.7 2.8 0.08 13.2 2.8 1.8 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) Myb_DNA-binding PF00249.31 CDJ41189.1 - 0.14 12.4 0.2 0.34 11.1 0.0 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain IHABP4_N PF16174.5 CDJ41189.1 - 2.6 8.6 11.7 1.5 9.4 7.9 2.0 1 1 1 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal K_channel_TID PF07941.11 CDJ41190.1 - 0.03 14.8 11.9 0.03 14.8 11.9 3.0 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain START PF01852.19 CDJ41192.1 - 4.6e-21 75.2 1.2 5.5e-21 74.9 0.2 1.6 2 0 0 2 2 2 1 START domain LapA_dom PF06305.11 CDJ41192.1 - 0.027 14.3 0.1 0.083 12.7 0.1 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2840 PF11000.8 CDJ41192.1 - 0.12 12.2 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2840) DUF3597 PF12200.8 CDJ41192.1 - 0.2 12.2 7.5 0.59 10.7 7.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) SpoIIIAH PF12685.7 CDJ41192.1 - 0.54 10.1 3.4 0.91 9.3 3.4 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein TFIIA PF03153.13 CDJ41193.1 - 3.1e-05 24.2 19.3 3.5e-05 24.0 19.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 CDJ41193.1 - 0.019 13.8 20.6 0.023 13.6 20.6 1.3 1 0 0 1 1 1 0 Androgen receptor Spt20 PF12090.8 CDJ41193.1 - 0.048 13.3 31.5 0.07 12.7 31.5 1.2 1 0 0 1 1 1 0 Spt20 family SARAF PF06682.12 CDJ41193.1 - 0.06 13.0 11.2 0.079 12.6 11.2 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Presenilin PF01080.17 CDJ41193.1 - 0.57 8.9 10.5 0.6 8.8 10.5 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ41193.1 - 0.75 8.0 15.9 0.8 7.9 15.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4551 PF15087.6 CDJ41193.1 - 0.75 8.6 11.4 0.96 8.2 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SPX PF03105.19 CDJ41193.1 - 1.1 9.0 16.7 1.3 8.9 16.7 1.1 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 CDJ41193.1 - 1.5 7.4 16.5 1.7 7.2 16.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP-alpha_N PF04086.13 CDJ41193.1 - 1.7 8.5 12.2 1.9 8.3 12.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal eIF-3_zeta PF05091.12 CDJ41193.1 - 1.8 7.4 9.5 2.1 7.2 9.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 CDJ41193.1 - 1.9 7.4 7.8 2.2 7.2 7.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S64 PF08192.11 CDJ41193.1 - 2.8 6.3 9.2 3.2 6.1 9.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 Nucleo_P87 PF07267.11 CDJ41193.1 - 2.8 6.7 11.5 3.3 6.4 11.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1180 PF06679.12 CDJ41193.1 - 3 8.2 11.1 4.5 7.7 11.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4820 PF16091.5 CDJ41193.1 - 3.1 7.1 10.5 6.4 6.1 10.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) Apt1 PF10351.9 CDJ41193.1 - 3.5 6.4 10.9 3.9 6.2 10.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain API5 PF05918.11 CDJ41193.1 - 6.8 5.4 13.1 8.7 5.0 13.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Menin PF05053.13 CDJ41193.1 - 7.2 4.8 9.0 7.9 4.7 9.0 1.1 1 0 0 1 1 1 0 Menin GREB1 PF15782.5 CDJ41193.1 - 9.1 3.3 11.4 9.7 3.2 11.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4175 PF13779.6 CDJ41193.1 - 9.2 4.0 20.2 11 3.8 20.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RskA PF10099.9 CDJ41194.1 - 0.0013 19.0 2.8 0.0013 19.0 2.8 14.8 5 3 3 8 8 8 1 Anti-sigma-K factor rskA IF4E PF01652.18 CDJ41195.1 - 4.3e-34 117.6 0.3 6e-34 117.1 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mago-bind PF09282.10 CDJ41196.1 - 1.9e-14 53.2 3.0 3e-14 52.6 3.0 1.3 1 0 0 1 1 1 1 Mago binding RhlB PF12300.8 CDJ41196.1 - 0.003 17.7 4.7 0.0057 16.8 4.7 1.5 1 0 0 1 1 1 1 ATP-dependent RNA helicase RhlB RAP1 PF07218.11 CDJ41196.1 - 0.0081 14.5 4.7 0.009 14.3 4.7 1.0 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) DUF3375 PF11855.8 CDJ41196.1 - 0.022 13.7 7.3 0.026 13.5 7.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3375) Macoilin PF09726.9 CDJ41196.1 - 0.077 11.5 11.7 0.093 11.3 11.7 1.0 1 0 0 1 1 1 0 Macoilin family Meckelin PF09773.9 CDJ41196.1 - 0.13 10.3 0.7 0.16 10.1 0.7 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) DUF5539 PF17693.1 CDJ41196.1 - 0.22 11.2 6.0 0.38 10.4 6.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5539) HNF-1_N PF04814.13 CDJ41196.1 - 1.2 9.7 9.1 3 8.4 9.1 1.8 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Otopetrin PF03189.13 CDJ41198.1 - 0.00072 18.5 0.0 52 2.5 0.0 2.4 1 1 1 2 2 2 1 Otopetrin Cys_Met_Meta_PP PF01053.20 CDJ41199.1 - 1.4e-113 379.3 0.0 1.2e-64 218.2 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CDJ41199.1 - 0.0012 18.3 0.4 0.0018 17.7 0.0 1.4 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CDJ41199.1 - 0.093 11.9 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II NAPRTase_C PF17956.1 CDJ41201.1 - 3.3e-26 91.9 0.0 4.8e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 CDJ41201.1 - 1.8e-11 44.1 0.0 3.6e-11 43.1 0.0 1.4 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF4179 PF13786.6 CDJ41202.1 - 0.054 14.0 0.4 0.096 13.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Velvet PF11754.8 CDJ41202.1 - 0.15 11.9 19.5 0.2 11.6 19.5 1.2 1 0 0 1 1 1 0 Velvet factor TFIIA PF03153.13 CDJ41202.1 - 0.22 11.5 51.2 0.35 10.8 51.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ41202.1 - 0.36 9.5 22.0 0.4 9.4 22.0 1.0 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ41202.1 - 0.69 8.1 42.1 0.79 7.9 42.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CCSAP PF15748.5 CDJ41202.1 - 1.1 9.4 22.8 1.2 9.2 22.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TCP PF03634.13 CDJ41202.1 - 1.5 9.4 15.4 2.1 8.9 15.4 1.3 1 0 0 1 1 1 0 TCP family transcription factor SID-1_RNA_chan PF13965.6 CDJ41202.1 - 1.5 7.1 3.5 1.6 7.0 3.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FAM60A PF15396.6 CDJ41202.1 - 1.6 8.7 12.2 2 8.4 12.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4045 PF13254.6 CDJ41202.1 - 1.6 8.3 22.5 1.8 8.1 22.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) HemX PF04375.14 CDJ41202.1 - 1.6 7.9 32.6 2 7.6 32.6 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Endostatin PF06482.11 CDJ41202.1 - 1.8 7.9 24.3 2.1 7.7 24.3 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin RR_TM4-6 PF06459.12 CDJ41202.1 - 2.2 8.0 19.8 2.6 7.8 19.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lin-8 PF03353.15 CDJ41202.1 - 2.5 7.6 23.8 3 7.3 23.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF908 PF06012.12 CDJ41202.1 - 2.5 7.4 16.3 2.9 7.2 16.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) eIF-3_zeta PF05091.12 CDJ41202.1 - 2.7 6.8 18.0 3.1 6.7 18.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Gti1_Pac2 PF09729.9 CDJ41202.1 - 2.9 8.0 15.4 3.8 7.6 15.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family MAJIN PF15077.6 CDJ41202.1 - 3.3 7.4 15.0 3.9 7.2 15.0 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Neur_chan_memb PF02932.16 CDJ41202.1 - 3.5 7.6 17.1 3.9 7.5 17.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 CDJ41202.1 - 3.9 6.6 13.7 5 6.3 13.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Maf1 PF09174.10 CDJ41202.1 - 4.2 7.5 8.0 5.6 7.1 8.0 1.3 1 0 0 1 1 1 0 Maf1 regulator CLN3 PF02487.17 CDJ41202.1 - 4.5 6.2 11.4 4.8 6.1 11.4 1.2 1 0 0 1 1 1 0 CLN3 protein DUF4638 PF15472.6 CDJ41202.1 - 6.6 6.4 14.8 8.4 6.0 14.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) CSG2 PF16965.5 CDJ41202.1 - 7.2 5.4 4.9 7.9 5.3 4.9 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DUF1387 PF07139.11 CDJ41202.1 - 7.9 6.1 19.9 9.3 5.9 19.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) ALMT PF11744.8 CDJ41202.1 - 9.3 4.9 14.9 11 4.8 14.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ41202.1 - 9.4 5.1 19.7 11 5.0 19.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DDHD PF02862.17 CDJ41204.1 - 0.0063 16.7 0.1 0.0066 16.6 0.1 1.0 1 0 0 1 1 1 1 DDHD domain Spt20 PF12090.8 CDJ41204.1 - 0.052 13.2 2.7 0.055 13.1 2.7 1.1 1 0 0 1 1 1 0 Spt20 family Feld-I_B PF09252.10 CDJ41205.1 - 5.7 7.0 29.7 27 4.8 0.2 7.5 1 1 7 9 9 9 0 Allergen Fel d I-B chain SF-assemblin PF06705.11 CDJ41207.1 - 7.7e-62 208.8 26.3 8.8e-62 208.7 26.3 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Gp58 PF07902.11 CDJ41207.1 - 0.0083 14.5 1.2 0.0083 14.5 1.2 1.9 1 1 1 2 2 2 1 gp58-like protein RT_RNaseH PF17917.1 CDJ41207.1 - 0.066 13.5 0.6 1 9.7 0.1 2.4 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DUF1664 PF07889.12 CDJ41207.1 - 0.14 12.2 10.9 0.12 12.4 2.4 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) FlgM PF04316.13 CDJ41207.1 - 6.3 7.2 10.9 15 6.1 4.2 3.2 2 1 0 2 2 2 0 Anti-sigma-28 factor, FlgM LYRIC PF15686.5 CDJ41208.1 - 0.44 10.1 14.1 0.54 9.8 14.1 1.0 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family SLC12 PF03522.15 CDJ41208.1 - 6.9 5.6 11.7 8.1 5.3 11.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 MIase PF02426.16 CDJ41209.1 - 0.37 11.0 13.3 0.16 12.2 3.4 2.9 3 0 0 3 3 3 0 Muconolactone delta-isomerase DUF2407 PF10302.9 CDJ41209.1 - 5.2 7.7 11.0 0.67 10.5 2.4 2.9 2 1 1 3 3 3 0 DUF2407 ubiquitin-like domain CCSAP PF15748.5 CDJ41209.1 - 5.8 7.0 18.5 0.7 10.0 10.9 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF4765 PF15962.5 CDJ41210.1 - 0.052 11.5 0.4 0.072 11.0 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4765) TFIIA PF03153.13 CDJ41210.1 - 0.48 10.4 18.3 0.7 9.8 18.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 CDJ41211.1 - 2 8.2 28.7 3.7 7.4 3.1 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Macoilin PF09726.9 CDJ41211.1 - 9 4.7 33.0 13 4.2 33.0 1.1 1 0 0 1 1 1 0 Macoilin family Laminin_G_3 PF13385.6 CDJ41212.1 - 2.4e-05 24.5 0.0 0.04 14.1 0.0 3.0 2 1 1 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily Apt1 PF10351.9 CDJ41212.1 - 1.6 7.5 3.2 2.2 7.0 3.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Filament_head PF04732.14 CDJ41212.1 - 2.7 8.9 27.2 2 9.4 7.3 4.0 4 0 0 4 4 4 0 Intermediate filament head (DNA binding) region DUF4220 PF13968.6 CDJ41213.1 - 0.00015 21.3 0.1 0.00056 19.4 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4220) TPR_2 PF07719.17 CDJ41213.1 - 0.015 15.4 3.6 3.7 7.9 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AnfO_nitrog PF09582.10 CDJ41213.1 - 0.043 13.1 1.6 0.072 12.4 1.6 1.3 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) DUF2126 PF09899.9 CDJ41213.1 - 0.1 10.6 1.2 0.14 10.2 1.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Tim54 PF11711.8 CDJ41213.1 - 0.11 11.3 1.6 0.19 10.5 1.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ribosomal_60s PF00428.19 CDJ41213.1 - 0.36 11.5 26.2 1.7 9.3 2.4 3.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein Lin-8 PF03353.15 CDJ41213.1 - 5.2 6.5 13.2 1.2 8.6 6.7 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist RTX PF02382.15 CDJ41213.1 - 7.5 6.1 12.9 0.46 10.1 0.3 2.3 2 0 0 2 2 2 0 N-terminal domain in RTX protein SUIM_assoc PF16619.5 CDJ41214.1 - 0.071 13.2 0.0 0.071 13.2 0.0 4.9 3 2 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Apt1 PF10351.9 CDJ41214.1 - 1.7 7.4 20.5 0.54 9.1 1.8 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain CbtB PF09489.10 CDJ41214.1 - 2.6 8.2 6.8 0.43 10.7 1.8 2.3 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Menin PF05053.13 CDJ41214.1 - 4.2 5.6 10.5 2.2 6.5 0.4 2.2 2 0 0 2 2 2 0 Menin DUF2721 PF11026.8 CDJ41215.1 - 0.0015 18.4 0.5 0.0018 18.2 0.5 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2721) Seryl_tRNA_N PF02403.22 CDJ41215.1 - 0.0072 16.5 0.7 0.0078 16.4 0.7 1.1 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 CDJ41215.1 - 0.017 15.2 7.3 0.02 15.0 7.3 1.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 CDJ41215.1 - 0.019 15.2 4.7 0.022 15.0 4.7 1.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3391 PF11871.8 CDJ41215.1 - 0.069 13.7 1.7 0.078 13.5 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Casc1_N PF15927.5 CDJ41215.1 - 10 5.8 12.2 16 5.1 12.2 1.5 1 1 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Flavoprotein PF02441.19 CDJ41216.1 - 1.6e-36 125.5 0.0 3.3e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 Flavoprotein DUF2284 PF10050.9 CDJ41216.1 - 3.2 7.5 8.5 29 4.3 8.1 2.2 1 1 0 1 1 1 0 Predicted metal-binding protein (DUF2284) PAT1 PF09770.9 CDJ41216.1 - 9.6 4.3 42.1 11 4.2 42.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Phage_holin_3_2 PF04550.12 CDJ41217.1 - 0.21 12.1 1.7 0.5 10.9 0.6 2.1 1 1 1 2 2 2 0 Phage holin family 2 Rad60-SLD PF11976.8 CDJ41218.1 - 2.9e-23 81.5 0.0 2.9e-23 81.5 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDJ41218.1 - 3.5e-11 42.7 0.0 3.5e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family YukD PF08817.10 CDJ41218.1 - 0.11 13.2 0.1 0.26 12.0 0.1 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD zf-CSL PF05207.13 CDJ41219.1 - 7.6e-15 54.4 0.0 1.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 CSL zinc finger Hamartin PF04388.12 CDJ41219.1 - 1.6 7.3 4.1 2 7.0 4.1 1.1 1 0 0 1 1 1 0 Hamartin protein Peptidase_C14 PF00656.22 CDJ41220.1 - 2.5e-12 47.3 0.0 2.5e-12 47.3 0.0 2.4 2 1 0 2 2 2 1 Caspase domain SR-25 PF10500.9 CDJ41220.1 - 1.6e-05 24.6 9.5 1.6e-05 24.6 9.5 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Pex14_N PF04695.13 CDJ41220.1 - 0.0053 17.4 4.1 0.0053 17.4 4.1 6.7 1 1 2 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IMUP PF15761.5 CDJ41220.1 - 0.023 15.4 9.6 0.023 15.4 9.6 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein PBP1_TM PF14812.6 CDJ41221.1 - 0.29 11.5 8.7 0.38 11.2 8.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Afi1 PF07792.12 CDJ41221.1 - 4.3 7.8 18.3 5 7.6 18.3 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Zip PF02535.22 CDJ41221.1 - 5.1 6.2 21.6 5.5 6.1 21.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter CYSTM PF12734.7 CDJ41223.1 - 0.09 13.1 12.5 0.34 11.3 12.5 2.0 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Spt20 PF12090.8 CDJ41223.1 - 3.8 7.1 9.8 5.8 6.5 9.8 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ41223.1 - 8 6.6 13.2 0.38 10.9 6.9 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Sin_N PF04801.13 CDJ41224.1 - 0.0019 17.5 3.0 0.0026 17.0 3.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region Peptidase_M64 PF09471.10 CDJ41224.1 - 0.027 14.0 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 IgA Peptidase M64 FeoB_associated PF12669.7 CDJ41224.1 - 0.063 13.7 1.3 0.12 12.8 1.3 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein SUIM_assoc PF16619.5 CDJ41225.1 - 0.01 15.9 7.7 0.01 15.9 7.7 5.0 5 1 1 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ41225.1 - 8.3 6.0 30.6 1.7 8.2 1.0 2.5 2 0 0 2 2 2 0 Spt20 family MAP70 PF07058.11 CDJ41225.1 - 9.9 4.8 18.5 14 4.2 18.5 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 Syntaphilin PF15290.6 CDJ41226.1 - 3.4 7.2 9.1 4.2 6.9 9.1 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Hat1_N PF10394.9 CDJ41229.1 - 1.3e-14 54.8 0.0 1.5e-14 54.6 0.0 1.0 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus AP2 PF00847.20 CDJ41230.1 - 5.3e-13 49.0 1.3 5.3e-13 49.0 1.3 1.7 2 0 0 2 2 2 1 AP2 domain V_ATPase_I PF01496.19 CDJ41230.1 - 1.6 6.6 15.4 2.1 6.2 15.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S15 PF02129.18 CDJ41231.1 - 2 7.9 16.7 0.22 11.1 10.6 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Herpes_LMP1 PF05297.11 CDJ41232.1 - 0.085 12.0 1.5 0.3 10.2 1.4 1.8 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Jnk-SapK_ap_N PF09744.9 CDJ41232.1 - 1 9.5 19.5 1.7 8.9 19.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 COMM_domain PF07258.14 CDJ41232.1 - 1.4 9.1 5.6 2.6 8.2 5.6 1.4 1 0 0 1 1 1 0 COMM domain ZYG-11_interact PF05884.12 CDJ41232.1 - 2.5 7.5 10.3 4.3 6.7 10.3 1.4 1 1 0 1 1 1 0 Interactor of ZYG-11 Exonuc_VII_L PF02601.15 CDJ41232.1 - 2.5 7.6 20.5 3.8 7.0 20.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Kinesin PF00225.23 CDJ41234.1 - 6.2e-41 140.4 0.1 8.5e-41 140.0 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Img2 PF05046.14 CDJ41235.1 - 1.1e-08 35.2 0.1 1.7e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Adeno_PIX PF03955.14 CDJ41235.1 - 4 7.6 17.3 0.051 13.7 4.0 2.4 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Peptidase_C78 PF07910.13 CDJ41237.1 - 2.2e-23 82.8 0.0 1.3e-22 80.4 0.0 2.3 1 0 0 1 1 1 1 Peptidase family C78 Caldesmon PF02029.15 CDJ41237.1 - 5.8 5.6 53.1 32 3.1 0.1 2.7 2 1 0 2 2 2 0 Caldesmon DUF4174 PF13778.6 CDJ41238.1 - 0.039 14.4 2.3 0.072 13.6 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Macoilin PF09726.9 CDJ41238.1 - 0.051 12.1 21.3 0.068 11.7 21.3 1.1 1 0 0 1 1 1 0 Macoilin family RusA PF05866.11 CDJ41238.1 - 0.26 11.9 3.4 1.1 9.8 3.1 2.1 2 0 0 2 2 2 0 Endodeoxyribonuclease RusA TFIIA PF03153.13 CDJ41238.1 - 0.55 10.2 22.3 0.72 9.8 22.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ41238.1 - 0.77 8.0 16.7 0.89 7.7 16.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.9 CDJ41238.1 - 1.5 7.6 15.8 1.8 7.3 15.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF572 PF04502.13 CDJ41238.1 - 5.2 6.6 14.0 7 6.2 14.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DNA_pol3_a_NII PF11490.8 CDJ41238.1 - 5.4 6.9 7.8 1.1 9.1 3.3 1.9 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus II Acatn PF13000.7 CDJ41239.1 - 2.7e-27 95.5 2.8 1.2e-26 93.4 2.4 2.0 1 1 1 2 2 2 1 Acetyl-coenzyme A transporter 1 MFS_1 PF07690.16 CDJ41239.1 - 0.0038 16.2 7.1 0.0038 16.2 7.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily AtpR PF12966.7 CDJ41239.1 - 0.13 12.8 4.9 4.3 7.9 0.6 2.4 2 1 0 2 2 2 0 N-ATPase, AtpR subunit SR-25 PF10500.9 CDJ41239.1 - 0.74 9.4 9.8 0.93 9.1 9.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mito_carr PF00153.27 CDJ41240.1 - 5.2e-66 218.6 3.1 6.5e-24 83.7 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GSHPx PF00255.19 CDJ41241.1 - 1.5e-27 95.3 0.6 2.1e-27 94.8 0.6 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CDJ41241.1 - 4.3e-08 33.1 0.2 4.6e-07 29.8 0.2 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ41241.1 - 6.4e-05 22.7 0.0 0.00037 20.2 0.0 2.0 2 0 0 2 2 2 1 Redoxin Shadoo PF14999.6 CDJ41241.1 - 0.23 11.6 9.9 0.37 10.9 9.9 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.19 CDJ41241.1 - 4.3 8.0 9.6 9.4 6.9 9.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein FtsJ PF01728.19 CDJ41242.1 - 4e-22 79.2 0.0 2.1e-19 70.3 0.0 2.5 2 0 0 2 2 2 2 FtsJ-like methyltransferase NYAP_N PF15439.6 CDJ41245.1 - 1e-05 25.0 3.5 1e-05 25.0 3.5 2.6 1 1 2 3 3 3 2 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter DDOST_48kD PF03345.14 CDJ41246.1 - 4.1e-49 167.6 0.0 2.4e-45 155.1 0.0 2.2 1 1 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta 2OG-FeII_Oxy_3 PF13640.6 CDJ41246.1 - 5.5e-10 40.0 0.0 4.8e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 CDJ41246.1 - 0.0015 17.7 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 Poxvirus C4/C10 protein zf-NOSIP PF15906.5 CDJ41247.1 - 8.5e-11 41.8 0.0 1.9e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 CDJ41247.1 - 0.094 12.8 0.3 0.094 12.8 0.3 1.7 2 0 0 2 2 2 0 RING-type zinc-finger Ima1_N PF09779.9 CDJ41247.1 - 0.15 12.9 3.8 0.28 12.0 3.6 1.5 1 1 0 1 1 1 0 Ima1 N-terminal domain Rtf2 PF04641.12 CDJ41247.1 - 0.16 11.3 0.0 0.16 11.3 0.0 3.0 1 1 1 2 2 2 0 Rtf2 RING-finger DUF3613 PF12266.8 CDJ41247.1 - 0.48 10.2 12.8 0.058 13.2 6.9 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3613) LPP20 PF02169.16 CDJ41247.1 - 0.94 9.9 5.3 1.9 8.9 5.3 1.5 1 0 0 1 1 1 0 LPP20 lipoprotein Bud13 PF09736.9 CDJ41249.1 - 1.3e-38 132.7 5.8 1.3e-38 132.7 5.8 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex AAA PF00004.29 CDJ41250.1 - 7.3e-39 133.2 0.0 1.4e-38 132.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ41250.1 - 1.2e-08 34.6 0.2 2.7e-08 33.5 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDJ41250.1 - 4.9e-05 23.8 3.6 0.0027 18.1 0.4 3.2 1 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CDJ41250.1 - 0.00038 20.7 0.3 0.052 13.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CDJ41250.1 - 0.0024 17.9 0.1 0.011 15.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CDJ41250.1 - 0.0039 16.4 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 CDJ41250.1 - 0.015 14.8 0.0 0.048 13.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 CDJ41250.1 - 0.02 14.4 0.2 0.037 13.5 0.2 1.3 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 CDJ41250.1 - 0.023 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 CDJ41250.1 - 0.026 14.5 0.1 0.097 12.6 0.1 2.1 1 1 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 CDJ41250.1 - 0.028 14.2 0.0 0.082 12.6 0.0 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CDJ41250.1 - 0.042 14.0 0.0 0.099 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CDJ41250.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CDJ41250.1 - 0.068 12.5 0.2 0.16 11.3 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CDJ41250.1 - 0.15 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 CDJ41250.1 - 0.16 11.9 0.1 0.29 11.1 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 CDJ41250.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.9 CDJ41251.1 - 0.41 10.2 9.8 0.75 9.4 9.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RRM_1 PF00076.22 CDJ41252.1 - 8e-37 124.9 0.1 4.4e-17 61.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ41252.1 - 1.3e-05 25.1 0.0 0.024 14.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CDJ41252.1 - 0.00011 22.0 0.0 0.008 16.0 0.0 2.7 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CDJ41252.1 - 0.014 15.5 0.0 0.63 10.2 0.0 3.1 2 1 0 2 2 2 0 RNA recognition motif DUF418 PF04235.12 CDJ41253.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF418) DUF2681 PF10883.8 CDJ41253.1 - 6.3 7.3 11.3 17 5.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) AMP-binding PF00501.28 CDJ41254.1 - 3.9e-86 289.3 0.0 6.4e-86 288.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ41254.1 - 4e-05 24.5 0.1 9.6e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 CDJ41256.1 - 2e-68 230.6 0.0 4.3e-68 229.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ41256.1 - 3e-33 115.2 0.0 6e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ41256.1 - 0.55 9.0 0.0 0.55 9.0 0.0 3.4 4 1 0 4 4 4 0 Fungal protein kinase LRR_4 PF12799.7 CDJ41257.1 - 4.4e-36 122.3 35.1 9.7e-08 32.2 2.9 7.3 2 1 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ41257.1 - 6.6e-32 109.1 28.0 1.7e-09 37.3 1.1 5.6 5 1 1 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 CDJ41257.1 - 3.9e-22 78.6 16.5 2.3e-06 27.2 0.8 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 CDJ41257.1 - 0.0013 19.0 36.1 0.97 10.2 0.2 9.3 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 CDJ41257.1 - 0.073 13.2 30.0 0.26 11.4 0.3 8.0 8 1 0 8 8 8 0 Leucine Rich repeat DUF2322 PF10084.9 CDJ41257.1 - 1.8 8.7 4.2 12 6.0 0.1 3.7 4 1 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2322) RCC1 PF00415.18 CDJ41258.1 - 3e-24 85.4 13.7 2.9e-08 34.2 0.3 7.7 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ41258.1 - 6.4e-17 60.9 29.4 5.1e-06 26.1 3.6 6.8 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat GpcrRhopsn4 PF10192.9 CDJ41259.1 - 0.0082 15.6 1.0 0.016 14.6 1.0 1.4 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 CDJ41259.1 - 0.013 14.7 1.9 0.015 14.6 1.1 1.4 1 1 0 1 1 1 0 Lung seven transmembrane receptor MIF4G PF02854.19 CDJ41260.1 - 2.4e-31 109.1 1.9 3.7e-31 108.4 1.9 1.3 1 0 0 1 1 1 1 MIF4G domain SPX PF03105.19 CDJ41260.1 - 7.2 6.4 8.7 3.5 7.4 2.7 2.5 2 0 0 2 2 2 0 SPX domain Dehydrin PF00257.19 CDJ41261.1 - 2.1 8.9 4.7 3.1 8.3 4.7 1.2 1 0 0 1 1 1 0 Dehydrin Spt20 PF12090.8 CDJ41262.1 - 0.36 10.4 7.8 0.33 10.5 7.8 1.2 1 0 0 1 1 1 0 Spt20 family Adaptin_N PF01602.20 CDJ41263.1 - 1.1e-54 186.0 1.7 9.6e-32 110.2 0.5 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 CDJ41263.1 - 4.6e-07 30.0 2.9 4.7e-07 30.0 0.2 2.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDJ41263.1 - 0.78 10.2 13.9 5.2 7.6 0.1 5.7 5 0 0 5 5 5 0 HEAT repeat SAP PF02037.27 CDJ41264.1 - 3.3e-14 52.2 2.8 3.6e-14 52.1 0.1 2.4 3 0 0 3 3 3 1 SAP domain Tho1_MOS11_C PF18592.1 CDJ41264.1 - 8.9e-08 31.8 26.3 0.01 15.6 2.0 4.4 2 2 2 4 4 4 4 Tho1/MOS11 C-terminal domain HeH PF12949.7 CDJ41264.1 - 0.0016 18.1 0.0 0.0043 16.7 0.0 1.6 1 0 0 1 1 1 1 HeH/LEM domain FANC_SAP PF18081.1 CDJ41264.1 - 0.03 14.5 1.5 0.03 14.5 1.5 2.4 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Statherin PF03875.13 CDJ41264.1 - 0.51 10.5 0.2 0.51 10.5 0.2 3.9 6 0 0 6 6 6 0 Statherin RNA_pol_Rpb1_5 PF04998.17 CDJ41265.1 - 1.9e-52 178.3 0.0 2.3e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 PucR PF07905.11 CDJ41265.1 - 0.069 13.4 0.0 0.4 11.0 0.0 2.1 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family SR-25 PF10500.9 CDJ41265.1 - 3 7.4 5.6 4.2 6.9 5.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNA_pol_Rpb1_2 PF00623.20 CDJ41266.1 - 1.1e-66 224.2 0.0 1.6e-66 223.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 CDJ41266.1 - 6.5e-37 127.5 0.0 9.3e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 CDJ41266.1 - 1.8e-30 106.0 0.0 2.7e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CDJ41266.1 - 7e-27 93.5 0.0 1.6e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 PF04998.17 CDJ41266.1 - 1.5e-18 67.2 0.1 2.3e-18 66.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Ribosomal_60s PF00428.19 CDJ41266.1 - 0.024 15.2 6.4 0.065 13.8 6.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Sybindin PF04099.12 CDJ41268.1 - 1.9e-16 60.3 0.0 2.3e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Pex2_Pex12 PF04757.14 CDJ41269.1 - 8.4e-17 61.5 0.0 9.1e-16 58.1 0.0 2.4 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CDJ41269.1 - 0.00013 21.8 2.6 0.0003 20.6 2.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ41269.1 - 0.024 15.0 5.2 0.052 13.9 5.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ41269.1 - 0.027 14.3 4.0 0.054 13.3 4.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ41269.1 - 2.3 8.4 6.2 6.2 7.1 6.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING IBN_N PF03810.19 CDJ41270.1 - 6.3e-06 26.0 1.0 3.1e-05 23.8 0.1 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Peptidase_M99_m PF17130.4 CDJ41270.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 beta-barrel domain of carboxypeptidase M99 RPN6_N PF18055.1 CDJ41270.1 - 0.089 13.2 0.1 0.46 10.9 0.1 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain Hyr1 PF15789.5 CDJ41270.1 - 0.17 11.5 0.8 7.3 6.2 0.2 2.5 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 DUF4351 PF14261.6 CDJ41272.1 - 0.051 13.6 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) IL13 PF03487.13 CDJ41272.1 - 0.097 12.4 0.5 0.14 11.9 0.4 1.4 1 1 0 1 1 1 0 Interleukin-13 R3H-assoc PF13902.6 CDJ41273.1 - 0.031 14.7 0.5 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 R3H-associated N-terminal domain Methyltr_RsmB-F PF01189.17 CDJ41274.1 - 3.1e-26 92.3 0.0 1.1e-18 67.6 0.0 2.2 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CDJ41274.1 - 0.0041 17.2 0.0 0.017 15.2 0.0 2.0 1 1 1 2 2 2 1 FtsJ-like methyltransferase HsbA PF12296.8 CDJ41275.1 - 0.16 12.4 1.1 2.6 8.5 0.2 2.7 2 0 0 2 2 2 0 Hydrophobic surface binding protein A DUF4407 PF14362.6 CDJ41275.1 - 1.4 8.2 31.6 0.01 15.2 6.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MgtE PF01769.16 CDJ41276.1 - 0.35 11.3 1.5 0.71 10.3 1.5 1.4 1 0 0 1 1 1 0 Divalent cation transporter DUF1084 PF06454.11 CDJ41277.1 - 1.5e-11 44.2 3.9 2.2e-11 43.6 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) L27 PF02828.16 CDJ41279.1 - 0.12 12.1 0.3 0.24 11.2 0.3 1.5 1 0 0 1 1 1 0 L27 domain TAL_FSA PF00923.19 CDJ41280.1 - 4.6e-99 331.4 2.7 5.4e-99 331.2 2.7 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Sod_Fe_N PF00081.22 CDJ41281.1 - 5.3e-35 119.7 0.3 9.2e-35 119.0 0.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 CDJ41281.1 - 4.1e-33 113.6 0.7 2.9e-32 110.9 0.0 2.4 2 1 1 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Peptidase_M16 PF00675.20 CDJ41282.1 - 3.3e-49 166.7 0.1 1.6e-48 164.5 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDJ41282.1 - 6.8e-29 101.2 0.0 2.3e-28 99.5 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Hydrolase_4 PF12146.8 CDJ41283.1 - 7.1e-11 41.8 0.0 7.1e-11 41.8 0.0 4.9 5 1 1 6 6 6 2 Serine aminopeptidase, S33 PHD_2 PF13831.6 CDJ41283.1 - 0.00019 20.9 28.0 0.013 15.1 2.0 4.7 4 0 0 4 4 4 3 PHD-finger FSH1 PF03959.13 CDJ41283.1 - 0.00035 20.3 0.0 0.00035 20.3 0.0 3.0 3 1 0 3 3 3 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 CDJ41283.1 - 0.00044 20.0 0.1 0.00044 20.0 0.1 4.1 3 0 0 3 3 3 1 alpha/beta hydrolase fold PRC2_HTH_1 PF18118.1 CDJ41286.1 - 0.053 14.3 0.4 0.076 13.8 0.4 1.2 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain CDT1 PF08839.11 CDJ41287.1 - 0.03 14.6 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 DNA replication factor CDT1 like INCA1 PF15142.6 CDJ41287.1 - 0.034 14.2 0.3 0.069 13.2 0.3 1.6 1 0 0 1 1 1 0 INCA1 SUIM_assoc PF16619.5 CDJ41287.1 - 1.5 8.9 8.2 0.77 9.9 3.7 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ41288.1 - 0.0022 17.7 13.7 0.0027 17.4 13.7 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ41288.1 - 0.0096 16.0 11.6 0.011 15.7 11.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ41288.1 - 0.035 14.2 16.4 0.85 9.7 14.8 2.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Pex14_N PF04695.13 CDJ41288.1 - 0.13 12.9 9.5 0.19 12.4 9.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rsc14 PF08586.10 CDJ41288.1 - 0.15 12.9 4.4 0.88 10.4 2.6 2.3 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Ndc1_Nup PF09531.10 CDJ41288.1 - 0.2 10.3 4.1 0.26 9.9 4.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Roughex PF06020.11 CDJ41288.1 - 0.22 10.6 6.9 0.28 10.2 6.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein ALMT PF11744.8 CDJ41288.1 - 0.22 10.3 3.4 0.28 10.0 3.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter baeRF_family7 PF18849.1 CDJ41288.1 - 0.25 11.5 0.0 0.25 11.5 0.0 2.1 1 1 1 2 2 1 0 Bacterial archaeo-eukaryotic release factor family 7 DUF2722 PF10846.8 CDJ41288.1 - 0.31 9.9 17.5 0.39 9.6 17.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Rpp20 PF12328.8 CDJ41288.1 - 0.36 10.8 4.2 0.68 9.9 4.2 1.4 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P DUF4834 PF16118.5 CDJ41288.1 - 0.44 11.5 5.8 0.76 10.8 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4820 PF16091.5 CDJ41288.1 - 0.46 9.8 7.4 0.65 9.3 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PepSY_TM PF03929.16 CDJ41288.1 - 0.64 9.6 2.8 0.8 9.3 2.8 1.3 1 0 0 1 1 1 0 PepSY-associated TM region Presenilin PF01080.17 CDJ41288.1 - 3.4 6.3 7.2 4.2 6.0 7.2 1.1 1 0 0 1 1 1 0 Presenilin HEAT_PBS PF03130.16 CDJ41288.1 - 3.9 8.4 6.2 3 8.8 0.3 3.1 2 1 0 2 2 2 0 PBS lyase HEAT-like repeat Med3 PF11593.8 CDJ41288.1 - 5.7 6.0 12.9 9.2 5.3 12.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4770 PF15994.5 CDJ41289.1 - 0.0089 16.3 6.1 0.8 9.9 0.4 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4770) Spt20 PF12090.8 CDJ41289.1 - 0.034 13.8 28.1 0.27 10.8 5.3 2.3 2 0 0 2 2 2 0 Spt20 family TERB2 PF15101.6 CDJ41289.1 - 0.12 12.4 11.2 0.068 13.2 0.7 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 MAP65_ASE1 PF03999.12 CDJ41289.1 - 0.52 9.0 10.6 0.5 9.0 3.5 2.1 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) DMAP1 PF05499.12 CDJ41289.1 - 4.9 7.0 12.9 1.8 8.4 4.0 2.2 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) eIF-3_zeta PF05091.12 CDJ41289.1 - 8 5.3 11.2 7.8 5.3 0.4 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EPL1 PF10513.9 CDJ41289.1 - 8.2 6.8 11.6 12 6.3 0.7 2.3 2 1 0 2 2 2 0 Enhancer of polycomb-like Cpn60_TCP1 PF00118.24 CDJ41292.1 - 2.9e-140 468.2 1.9 3.9e-103 345.7 0.5 2.3 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family LMBR1 PF04791.16 CDJ41292.1 - 0.08 11.8 0.8 0.1 11.5 0.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 CDJ41292.1 - 0.91 9.0 9.0 1.7 8.1 9.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_C1 PF00112.23 CDJ41293.1 - 7.3e-54 183.1 0.0 2.7e-53 181.3 0.0 1.7 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ41293.1 - 0.013 14.3 1.3 0.056 12.2 0.1 1.9 2 0 0 2 2 2 0 Peptidase C1-like family RCDG1 PF15725.5 CDJ41293.1 - 0.15 12.5 5.6 0.14 12.6 3.9 1.9 1 1 0 1 1 1 0 Renal cancer differentiation gene 1 protein Spore_coat_CotO PF14153.6 CDJ41294.1 - 0.004 17.1 9.5 0.004 17.1 9.5 2.8 3 0 0 3 3 3 1 Spore coat protein CotO FAM60A PF15396.6 CDJ41294.1 - 0.055 13.5 6.7 0.12 12.4 6.7 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 CDJ41294.1 - 0.12 10.5 9.6 0.2 9.8 9.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein O-antigen_lig PF13425.6 CDJ41294.1 - 0.17 10.6 0.3 0.25 10.1 0.3 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CSG2 PF16965.5 CDJ41294.1 - 0.33 9.8 1.5 0.59 9.0 1.5 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4746 PF15928.5 CDJ41294.1 - 0.76 9.1 6.5 0.47 9.8 3.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Peptidase_S64 PF08192.11 CDJ41294.1 - 0.91 7.9 9.5 1.4 7.4 9.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF1980 PF09323.10 CDJ41294.1 - 1.4 8.8 7.2 1.3 8.9 3.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) SLC12 PF03522.15 CDJ41294.1 - 2.6 7.0 13.5 0.82 8.6 10.7 1.5 2 0 0 2 2 2 0 Solute carrier family 12 Connexin PF00029.19 CDJ41294.1 - 2.7 7.7 10.0 0.061 13.1 3.2 1.7 2 0 0 2 2 2 0 Connexin Sin_N PF04801.13 CDJ41294.1 - 3.6 6.7 29.9 0.79 8.9 24.9 2.3 2 0 0 2 2 2 0 Sin-like protein conserved region Lin-8 PF03353.15 CDJ41294.1 - 8.3 5.9 18.1 1.2 8.6 14.1 1.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist WBP-1 PF11669.8 CDJ41295.1 - 0.0039 17.8 1.1 0.0039 17.8 1.1 3.4 2 2 2 4 4 4 1 WW domain-binding protein 1 YajC PF02699.15 CDJ41295.1 - 0.022 14.6 0.4 0.022 14.6 0.4 4.6 4 1 0 4 4 4 0 Preprotein translocase subunit ETRAMP PF09716.10 CDJ41295.1 - 0.033 14.3 1.2 8.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) ANAPC_CDC26 PF10471.9 CDJ41295.1 - 0.033 15.0 0.7 0.033 15.0 0.7 4.3 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit CDC26 PCYCGC PF13798.6 CDJ41295.1 - 0.52 10.1 8.4 0.77 9.6 3.6 2.6 2 1 1 3 3 3 0 Protein of unknown function with PCYCGC motif YTH PF04146.15 CDJ41296.1 - 3.8e-27 95.3 2.6 2.5e-26 92.6 0.0 3.0 2 2 0 2 2 2 1 YT521-B-like domain DUF1388 PF07142.12 CDJ41296.1 - 0.0043 17.0 1.1 0.095 12.7 0.0 2.7 2 0 0 2 2 2 1 Repeat of unknown function (DUF1388) Ribosomal_60s PF00428.19 CDJ41296.1 - 0.066 13.8 0.9 0.066 13.8 0.9 3.4 2 1 0 2 2 2 0 60s Acidic ribosomal protein WW PF00397.26 CDJ41297.1 - 1.2e-15 57.2 8.8 1.4e-09 37.8 2.3 2.6 2 0 0 2 2 2 2 WW domain FF PF01846.19 CDJ41297.1 - 1.2e-13 51.0 14.9 6.5e-06 26.2 0.4 5.0 5 0 0 5 5 5 3 FF domain Trypan_PARP PF05887.11 CDJ41297.1 - 0.0047 16.9 7.3 0.0047 16.9 7.3 2.4 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Patatin PF01734.22 CDJ41297.1 - 0.13 12.4 2.4 0.11 12.6 0.5 1.9 2 0 0 2 2 2 0 Patatin-like phospholipase MFAP1 PF06991.11 CDJ41298.1 - 2.4e-64 217.2 29.0 2.4e-64 217.2 29.0 2.2 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing TFIIA PF03153.13 CDJ41298.1 - 0.00064 19.8 22.2 0.00082 19.5 22.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ41299.1 - 0.64 9.6 18.2 1.1 8.8 18.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 CDJ41299.1 - 3.5 8.2 9.6 0.34 11.5 2.4 2.5 2 0 0 2 2 2 0 Dehydrin DUF913 PF06025.12 CDJ41300.1 - 0.11 11.5 0.5 0.27 10.1 0.5 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CDJ41300.1 - 4.4 6.0 11.3 0.16 10.7 4.6 1.9 2 0 0 2 2 2 0 Presenilin eIF-3_zeta PF05091.12 CDJ41300.1 - 6.3 5.6 17.8 0.083 11.8 7.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 CDJ41300.1 - 6.6 6.3 35.0 0.059 13.0 19.8 2.8 3 0 0 3 3 3 0 Spt20 family CPSF100_C PF13299.6 CDJ41300.1 - 9.3 6.4 15.2 0.47 10.6 3.7 3.2 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal PCNA_N PF00705.18 CDJ41301.1 - 3.8e-23 81.6 0.1 5.2e-23 81.2 0.1 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 CDJ41301.1 - 0.066 12.7 0.1 0.08 12.4 0.1 1.1 1 0 0 1 1 1 0 Rad9 Ureide_permease PF07168.11 CDJ41301.1 - 0.16 10.7 0.0 0.16 10.7 0.0 2.4 3 0 0 3 3 3 0 Ureide permease Spt20 PF12090.8 CDJ41301.1 - 3.1 7.3 20.7 3.9 7.0 20.7 1.1 1 0 0 1 1 1 0 Spt20 family PCNA_C PF02747.15 CDJ41302.1 - 4.9e-14 52.6 0.0 5.3e-13 49.3 0.0 2.2 1 1 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Translin PF01997.16 CDJ41304.1 - 6.7e-29 101.3 1.1 1.5e-28 100.2 1.1 1.5 1 1 0 1 1 1 1 Translin family CPW_WPC PF09717.10 CDJ41305.1 - 1.3e-05 26.0 4.2 0.015 16.2 0.3 2.3 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) nlz1 PF12402.8 CDJ41305.1 - 0.046 14.2 0.3 0.11 13.0 0.3 1.6 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 RNA_Me_trans PF04252.13 CDJ41306.1 - 1.8e-48 164.8 0.0 2.3e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase bPH_6 PF10756.9 CDJ41306.1 - 0.29 11.3 3.2 3.1 8.0 0.7 2.8 2 1 1 3 3 3 0 Bacterial PH domain SSB PF00436.25 CDJ41307.1 - 1.2e-32 112.0 0.1 1.7e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family MOLO1 PF17175.4 CDJ41309.1 - 2.7e-06 27.5 0.2 5.9e-06 26.4 0.2 1.6 1 1 0 1 1 1 1 Modulator of levamisole receptor-1 PNK3P PF08645.11 CDJ41310.1 - 0.019 14.7 0.2 0.04 13.6 0.2 1.6 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase DUF1110 PF06533.12 CDJ41310.1 - 0.045 13.7 0.1 0.075 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) DUF2608 PF11019.8 CDJ41310.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) HAD_2 PF13419.6 CDJ41310.1 - 0.72 9.9 5.9 10 6.2 0.1 2.7 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Torus PF16131.5 CDJ41311.1 - 0.00077 20.1 9.2 0.0024 18.5 0.0 3.3 2 1 1 3 3 3 2 Torus domain RRM_1 PF00076.22 CDJ41311.1 - 0.0037 17.0 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) D_CNTX PF17492.2 CDJ41311.1 - 0.15 12.3 2.2 0.33 11.2 0.1 2.6 2 0 0 2 2 2 0 Delta Ctenitoxins RRM_1 PF00076.22 CDJ41313.1 - 6.5e-11 41.9 0.0 2e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CPW_WPC PF09717.10 CDJ41314.1 - 9.1e-48 161.1 14.1 1.4e-11 45.2 2.2 5.5 5 0 0 5 5 5 5 Plasmodium falciparum domain of unknown function (CPW_WPC) Cullin_binding PF03556.15 CDJ41315.1 - 7.4e-24 84.5 0.9 3.3e-16 59.8 0.0 2.1 2 0 0 2 2 2 2 Cullin binding Shadoo PF14999.6 CDJ41315.1 - 0.14 12.2 6.8 0.3 11.2 6.8 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.19 CDJ41315.1 - 0.97 10.1 8.4 1 10.0 7.1 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein ThiF PF00899.21 CDJ41316.1 - 5.7e-18 65.2 0.0 2.5e-13 49.9 0.0 2.9 1 1 0 2 2 2 2 ThiF family CK_II_beta PF01214.18 CDJ41316.1 - 0.2 11.5 0.1 1.7 8.4 0.0 2.1 1 1 1 2 2 2 0 Casein kinase II regulatory subunit IMUP PF15761.5 CDJ41316.1 - 0.84 10.3 8.7 0.05 14.3 3.1 1.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein K_channel_TID PF07941.11 CDJ41316.1 - 8.8 6.9 30.5 0.37 11.3 5.5 3.7 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain CAF1 PF04857.20 CDJ41317.1 - 7.7e-20 71.3 0.5 6.9e-09 35.3 0.0 4.3 2 1 2 4 4 4 3 CAF1 family ribonuclease Activator_LAG-3 PF11498.8 CDJ41317.1 - 0.00058 19.0 21.9 0.00058 19.0 21.9 1.7 2 0 0 2 2 2 1 Transcriptional activator LAG-3 Ribosomal_60s PF00428.19 CDJ41317.1 - 0.0056 17.3 3.9 0.0056 17.3 3.9 3.5 3 0 0 3 3 3 1 60s Acidic ribosomal protein Dicty_REP PF05086.12 CDJ41317.1 - 0.07 11.1 0.8 0.11 10.4 0.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MID_MedPIWI PF18296.1 CDJ41317.1 - 0.13 12.1 8.7 12 5.6 4.2 3.1 3 0 0 3 3 3 0 MID domain of medPIWI SUIM_assoc PF16619.5 CDJ41317.1 - 0.18 11.9 0.0 0.18 11.9 0.0 3.4 2 1 1 3 3 2 0 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 CDJ41317.1 - 1.7 7.3 9.9 0.023 13.5 2.7 1.5 2 0 0 2 2 2 0 Presenilin SpoIIP PF07454.11 CDJ41317.1 - 3.3 7.1 10.1 0.53 9.7 3.4 2.6 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) SR-25 PF10500.9 CDJ41317.1 - 7.4 6.1 21.6 0.35 10.4 7.7 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein CPSF100_C PF13299.6 CDJ41317.1 - 7.4 6.7 8.8 1.7 8.8 1.2 2.9 4 0 0 4 4 4 0 Cleavage and polyadenylation factor 2 C-terminal DUF5327 PF17261.2 CDJ41317.1 - 7.6 7.4 17.5 16 6.3 12.6 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Coilin_N PF15862.5 CDJ41317.1 - 8.7 6.1 13.5 30 4.4 0.2 3.4 3 0 0 3 3 3 0 Coilin N-terminus Mito_carr PF00153.27 CDJ41318.1 - 2.1e-46 155.8 21.0 6.4e-20 70.9 0.0 6.0 7 0 0 7 7 7 4 Mitochondrial carrier protein Serine_protease PF18405.1 CDJ41318.1 - 0.14 11.3 0.3 0.51 9.4 0.2 2.0 2 0 0 2 2 2 0 Gammaproteobacterial serine protease DUF3915 PF13054.6 CDJ41318.1 - 5.3 7.0 11.1 1.8 8.6 8.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Mre11_DNA_bind PF04152.14 CDJ41319.1 - 1.1e-26 94.2 0.0 1.8e-24 87.0 0.0 3.2 2 1 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CDJ41319.1 - 3.9e-14 53.6 1.7 1.9e-08 35.0 0.0 2.6 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ41319.1 - 7.9e-09 35.9 0.0 0.00057 20.1 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain EMC3_TMCO1 PF01956.16 CDJ41319.1 - 0.94 9.2 2.5 2 8.1 2.5 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like FXMRP1_C_core PF12235.8 CDJ41319.1 - 8.8 7.0 18.6 1.1 10.0 11.4 2.6 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal SlyX PF04102.12 CDJ41320.1 - 0.0041 17.7 11.0 1.3 9.7 0.0 3.9 3 0 0 3 3 3 2 SlyX DUF2205 PF10224.9 CDJ41320.1 - 0.027 14.5 4.3 0.032 14.2 1.1 2.6 2 0 0 2 2 2 0 Short coiled-coil protein Herpes_BLRF2 PF05812.12 CDJ41320.1 - 0.027 14.6 3.3 0.069 13.3 3.3 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Elf4 PF07011.11 CDJ41320.1 - 0.064 13.2 0.4 1.4 8.9 0.1 2.6 2 0 0 2 2 2 0 Early Flowering 4 domain FlaC_arch PF05377.11 CDJ41320.1 - 0.85 10.1 6.3 6.1 7.3 0.1 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 CDJ41320.1 - 1.1 9.8 24.5 3.7 8.1 0.9 3.6 3 0 0 3 3 3 0 Apg6 coiled-coil region GIT_CC PF16559.5 CDJ41320.1 - 6.8 6.6 8.9 3.9 7.4 0.3 3.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor RNA_pol_Rpb4 PF03874.16 CDJ41322.1 - 1.5e-05 25.3 0.0 5e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb4 DER1 PF04511.15 CDJ41323.1 - 3.3e-44 151.1 15.0 3.8e-44 150.9 15.0 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 CDJ41323.1 - 5.6e-06 26.4 15.8 9.8e-06 25.6 15.8 1.3 1 0 0 1 1 1 1 Rhomboid family DUF373 PF04123.13 CDJ41323.1 - 0.8 9.1 5.0 0.95 8.8 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) zf-B_box PF00643.24 CDJ41324.1 - 1.7e-12 47.3 14.0 2.3e-06 27.7 6.6 2.2 2 0 0 2 2 2 2 B-box zinc finger PARP PF00644.20 CDJ41324.1 - 0.0057 16.3 0.5 0.025 14.2 0.2 2.2 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Pec_lyase_N PF04431.13 CDJ41324.1 - 0.24 11.7 1.2 0.61 10.4 0.0 2.3 3 0 0 3 3 3 0 Pectate lyase, N terminus Cript PF10235.9 CDJ41324.1 - 4.1 8.0 5.8 3.2 8.4 3.6 2.0 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Leu_Phe_trans PF03588.14 CDJ41325.1 - 8.9e-15 54.6 0.0 1e-09 38.2 0.0 2.4 2 0 0 2 2 2 2 Leucyl/phenylalanyl-tRNA protein transferase Unstab_antitox PF09720.10 CDJ41326.1 - 0.029 14.4 2.9 3 8.0 0.4 3.2 3 0 0 3 3 3 0 Putative addiction module component Shadoo PF14999.6 CDJ41329.1 - 0.021 14.9 4.0 0.021 14.9 4.0 1.7 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DREPP PF05558.12 CDJ41329.1 - 0.051 13.5 0.4 0.094 12.6 0.4 1.4 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide ACDC PF14733.6 CDJ41330.1 - 2.6e-17 62.9 0.1 7.3e-17 61.5 0.1 1.8 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ41330.1 - 1.4e-09 38.0 0.2 1.4e-09 38.0 0.2 2.5 2 0 0 2 2 2 1 AP2 domain AAA_33 PF13671.6 CDJ41333.1 - 0.047 13.8 0.1 0.047 13.8 0.1 4.3 6 0 0 6 6 6 0 AAA domain RNA_ligase PF09414.10 CDJ41333.1 - 0.048 14.0 0.0 16 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA ligase DUF4992 PF16383.5 CDJ41334.1 - 0.075 12.6 0.1 0.13 11.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function PE-PPE PF08237.11 CDJ41335.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Hydrolase_3 PF08282.12 CDJ41336.1 - 2.2e-35 122.7 0.0 1.6e-19 70.6 0.0 2.0 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ41336.1 - 4e-10 39.6 0.0 0.00021 20.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CDJ41336.1 - 5.6e-09 36.6 0.1 0.044 14.0 0.0 3.3 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDJ41336.1 - 0.00078 19.5 0.1 0.0017 18.4 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 CDJ41336.1 - 0.0075 15.9 0.0 0.086 12.4 0.0 2.0 1 1 1 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) ATPgrasp_N PF18130.1 CDJ41336.1 - 0.0092 16.5 0.2 1 10.0 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp N-terminal domain HAD PF12710.7 CDJ41336.1 - 0.053 13.9 0.0 20 5.5 0.0 3.4 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 CDJ41336.1 - 0.077 12.1 0.0 0.94 8.6 0.0 2.2 2 0 0 2 2 2 0 Trehalose-phosphatase Robl_LC7 PF03259.17 CDJ41336.1 - 0.12 12.1 0.3 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Roadblock/LC7 domain zf-B_box PF00643.24 CDJ41337.1 - 7.3e-11 42.0 17.4 4.3e-06 26.8 5.3 3.0 3 0 0 3 3 3 2 B-box zinc finger DUF3135 PF11333.8 CDJ41337.1 - 0.0019 18.4 0.3 0.0068 16.6 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3135) PARP PF00644.20 CDJ41337.1 - 0.014 15.0 0.7 0.062 12.9 0.2 2.2 2 1 0 2 2 2 0 Poly(ADP-ribose) polymerase catalytic domain DUF4407 PF14362.6 CDJ41341.1 - 0.0012 18.2 3.1 0.0012 18.2 3.1 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4407) DUF45 PF01863.17 CDJ41341.1 - 2.8 7.9 8.9 0.33 10.9 3.4 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 RNB PF00773.19 CDJ41342.1 - 4.4e-16 59.1 1.5 7.1e-14 51.9 0.0 2.4 2 1 0 2 2 2 2 RNB domain TFIIA PF03153.13 CDJ41342.1 - 0.00077 19.6 33.5 0.015 15.3 9.9 2.4 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ41342.1 - 0.035 13.7 23.5 0.22 11.1 8.1 2.3 2 0 0 2 2 2 0 Spt20 family Imm40 PF15569.6 CDJ41342.1 - 0.21 11.7 0.0 0.4 10.8 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 40 DUF2722 PF10846.8 CDJ41342.1 - 0.22 10.4 19.3 0.68 8.8 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Pertus-S4-tox PF09275.10 CDJ41342.1 - 0.51 10.6 0.0 0.51 10.6 0.0 3.5 4 1 1 5 5 5 0 Pertussis toxin S4 subunit DUF4834 PF16118.5 CDJ41342.1 - 3 8.9 8.2 15 6.6 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Mus7 PF09462.10 CDJ41342.1 - 5.9 5.6 5.2 4 6.2 0.1 2.1 2 0 0 2 2 2 0 Mus7/MMS22 family 14-3-3 PF00244.20 CDJ41343.1 - 2e-11 43.8 0.8 2e-11 43.8 0.8 2.5 3 1 0 3 3 3 1 14-3-3 protein DUF2722 PF10846.8 CDJ41343.1 - 0.0037 16.3 2.0 0.0037 16.3 2.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ41343.1 - 0.057 14.1 0.7 0.057 14.1 0.7 3.2 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PI-PLC-X PF00388.19 CDJ41344.1 - 1.5e-48 164.1 0.0 2.3e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain RINGv PF12906.7 CDJ41345.1 - 4.3e-12 46.0 6.0 9.9e-12 44.8 6.0 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 CDJ41345.1 - 0.015 15.6 1.7 0.034 14.5 1.7 1.5 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 CDJ41345.1 - 0.13 12.4 1.4 0.29 11.3 1.4 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Mito_carr PF00153.27 CDJ41346.1 - 9.5e-10 38.3 0.0 0.0026 17.6 0.0 2.7 2 0 0 2 2 2 2 Mitochondrial carrier protein BAF1_ABF1 PF04684.13 CDJ41346.1 - 0.096 11.7 0.3 0.13 11.3 0.3 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SpoIIIAH PF12685.7 CDJ41346.1 - 0.42 10.4 8.2 54 3.5 11.1 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Apt1 PF10351.9 CDJ41346.1 - 1.5 7.6 10.2 4.7 6.0 6.2 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain SprA-related PF12118.8 CDJ41346.1 - 3.7 6.6 18.7 0.014 14.6 6.9 2.2 2 0 0 2 2 2 0 SprA-related family RskA PF10099.9 CDJ41347.1 - 0.0055 17.0 24.9 0.016 15.5 19.7 6.8 3 1 2 5 5 5 3 Anti-sigma-K factor rskA polyprenyl_synt PF00348.17 CDJ41348.1 - 5.3e-23 81.4 0.0 6.1e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Sec23_trunk PF04811.15 CDJ41349.1 - 1.3e-53 182.1 0.2 3.3e-46 157.8 0.0 2.2 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CDJ41349.1 - 3.8e-15 56.4 0.0 1.7e-14 54.3 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CDJ41349.1 - 9.9e-09 35.0 0.5 2e-08 34.0 0.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CDJ41349.1 - 1.4e-08 34.6 2.1 2.8e-08 33.7 2.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 CDJ41349.1 - 0.27 10.6 2.4 0.63 9.5 2.4 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Syja_N PF02383.18 CDJ41350.1 - 2.3e-49 168.5 0.0 2e-48 165.4 0.0 2.5 3 0 0 3 3 3 1 SacI homology domain Exo_endo_phos PF03372.23 CDJ41350.1 - 6.3e-09 35.7 0.0 2.1e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF755 PF05501.11 CDJ41350.1 - 0.0055 17.0 8.2 0.0055 17.0 8.2 7.7 8 0 0 8 8 8 1 Domain of unknown function (DUF755) SUIM_assoc PF16619.5 CDJ41350.1 - 0.037 14.1 0.4 0.037 14.1 0.4 8.0 7 0 0 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 PsbQ PF05757.11 CDJ41351.1 - 4.5 7.0 22.3 0.36 10.5 9.7 2.2 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) FGAR-AT_N PF18076.1 CDJ41352.1 - 0.22 11.5 6.7 0.61 10.1 6.7 1.8 1 1 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal TFIIA PF03153.13 CDJ41352.1 - 0.55 10.2 20.0 0.59 10.1 20.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ41352.1 - 0.94 8.3 12.7 0.88 8.4 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ41352.1 - 7 6.2 21.7 8 6.0 21.7 1.1 1 0 0 1 1 1 0 Spt20 family DUF3573 PF12097.8 CDJ41352.1 - 8 5.2 5.8 7.8 5.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Lyase_1 PF00206.20 CDJ41353.1 - 3.5e-21 75.9 0.4 6.8e-13 48.7 0.0 2.6 1 1 1 2 2 2 2 Lyase ASL_C PF08328.11 CDJ41353.1 - 3.4e-07 30.4 0.0 6.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal SUIM_assoc PF16619.5 CDJ41353.1 - 0.023 14.8 0.3 0.023 14.8 0.3 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MMU163 PF17119.5 CDJ41354.1 - 5.7 6.0 9.0 7.8 5.6 9.0 1.3 1 1 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Alba PF01918.21 CDJ41355.1 - 0.00091 19.0 0.6 0.004 16.9 0.6 1.8 1 1 0 1 1 1 1 Alba NTP_transf_2 PF01909.23 CDJ41356.1 - 0.005 17.1 0.0 0.0084 16.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase domain CmlA_N PF18456.1 CDJ41356.1 - 0.011 15.0 0.0 0.011 15.0 0.0 1.5 2 0 0 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain dCache_3 PF14827.6 CDJ41356.1 - 0.026 14.2 3.1 0.11 12.1 0.4 2.2 2 0 0 2 2 2 0 Double sensory domain of two-component sensor kinase TetR_C_20 PF17925.1 CDJ41356.1 - 0.036 14.4 0.5 0.036 14.4 0.5 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CASP_C PF08172.12 CDJ41356.1 - 0.5 9.7 5.1 1.2 8.5 5.1 1.6 1 0 0 1 1 1 0 CASP C terminal RskA PF10099.9 CDJ41356.1 - 0.73 10.1 30.6 0.028 14.7 9.7 2.7 1 1 2 3 3 3 0 Anti-sigma-K factor rskA KAR9 PF08580.10 CDJ41356.1 - 2 6.9 11.9 2.4 6.6 11.9 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Neugrin PF06413.11 CDJ41357.1 - 0.043 13.8 3.9 0.059 13.4 3.9 1.2 1 0 0 1 1 1 0 Neugrin Spt20 PF12090.8 CDJ41357.1 - 7.3 6.1 13.5 9.6 5.7 13.5 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ41357.1 - 7.6 6.4 16.2 11 5.9 16.2 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNase_H2-Ydr279 PF09468.10 CDJ41358.1 - 0.033 14.4 0.1 0.051 13.8 0.1 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain FAST_1 PF06743.15 CDJ41360.1 - 0.0018 18.2 0.4 6.6 6.8 0.0 4.5 3 1 2 5 5 5 3 FAST kinase-like protein, subdomain 1 Rootletin PF15035.6 CDJ41360.1 - 0.16 12.0 0.2 0.29 11.1 0.2 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Peptidase_M16_C PF05193.21 CDJ41362.1 - 2.6e-25 89.5 0.1 2.6e-13 50.4 0.0 3.9 2 2 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDJ41362.1 - 1e-15 58.0 0.3 6.7e-14 52.1 0.3 2.6 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) YicC_N PF03755.13 CDJ41362.1 - 0.095 13.2 1.2 0.51 10.8 0.0 2.6 3 0 0 3 3 3 0 YicC-like family, N-terminal region Trep_dent_lipo PF09710.10 CDJ41362.1 - 0.16 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) ALAD PF00490.21 CDJ41363.1 - 4.8e-129 430.1 0.0 5.7e-129 429.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Cnd2 PF05786.14 CDJ41363.1 - 0.28 9.8 2.7 0.38 9.4 2.7 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Nop14 PF04147.12 CDJ41363.1 - 0.79 7.9 6.6 0.96 7.6 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CDJ41363.1 - 0.86 7.8 2.5 1.2 7.4 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 CDJ41363.1 - 2.1 8.5 13.6 3.8 7.7 13.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 YL1 PF05764.13 CDJ41363.1 - 4.1 7.5 9.1 6.8 6.7 9.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein AP2 PF00847.20 CDJ41364.1 - 3.3e-06 27.2 0.8 1.1e-05 25.5 0.3 2.1 2 0 0 2 2 2 1 AP2 domain Methyltransf_23 PF13489.6 CDJ41365.1 - 2.2e-11 43.8 0.0 1.3e-10 41.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ41365.1 - 3.5e-10 39.9 0.0 7.9e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ41365.1 - 6.9e-09 36.3 0.0 2.6e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ41365.1 - 9.5e-09 35.9 0.1 3.5e-07 30.8 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ41365.1 - 0.00023 21.9 0.0 0.0044 17.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CDJ41365.1 - 0.023 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain EF-hand_6 PF13405.6 CDJ41367.1 - 0.00012 21.7 0.0 0.00052 19.7 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CDJ41367.1 - 0.00019 20.7 0.0 0.00072 18.9 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CDJ41367.1 - 0.019 15.4 0.2 0.081 13.4 0.0 2.2 3 0 0 3 3 3 0 EF-hand domain pair HSP90 PF00183.18 CDJ41370.1 - 1.2e-233 776.7 37.3 1.6e-233 776.3 37.3 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CDJ41370.1 - 2.9e-16 60.0 0.0 5.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDJ41370.1 - 7.9e-10 38.7 0.1 2.4e-09 37.1 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 CDJ41370.1 - 0.0039 17.2 0.2 0.016 15.3 0.2 2.0 1 0 0 1 1 1 1 Tumour suppressor protein Cofac_haem_bdg PF04187.13 CDJ41370.1 - 0.12 12.3 1.6 0.34 10.9 0.1 2.5 2 1 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN Zip PF02535.22 CDJ41370.1 - 0.18 11.0 3.2 0.29 10.3 3.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.16 CDJ41370.1 - 0.47 9.6 7.3 0.91 8.7 7.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.14 CDJ41370.1 - 2.3 8.6 10.6 4.8 7.6 10.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 CDJ41370.1 - 2.8 6.6 7.0 4.3 6.0 7.0 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CDJ41370.1 - 4.8 5.3 17.2 7.9 4.6 17.2 1.2 1 0 0 1 1 1 0 CDC45-like protein GH114_assoc PF14741.6 CDJ41371.1 - 0.16 12.2 0.1 0.39 10.9 0.1 1.6 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain SUIM_assoc PF16619.5 CDJ41372.1 - 0.025 14.7 1.9 0.025 14.7 1.9 7.4 3 2 3 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 Diphthamide_syn PF01866.17 CDJ41373.1 - 0.064 12.7 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative diphthamide synthesis protein Peptidase_S9 PF00326.21 CDJ41374.1 - 2e-06 27.5 25.5 5.7e-05 22.7 0.4 4.0 3 1 1 4 4 4 3 Prolyl oligopeptidase family RRM_1 PF00076.22 CDJ41375.1 - 1.3e-10 40.9 0.0 0.0085 15.9 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TrbC PF04956.13 CDJ41376.1 - 6.6 7.0 8.2 0.6 10.4 0.3 2.8 2 0 0 2 2 2 0 TrbC/VIRB2 family TAXi_N PF14543.6 CDJ41377.1 - 5.7e-11 43.0 1.2 5.7e-11 43.0 1.2 3.2 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp PF00026.23 CDJ41377.1 - 2.9e-08 33.5 0.0 0.00037 20.0 0.0 3.9 4 0 0 4 4 4 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 CDJ41377.1 - 8.7e-05 22.4 0.0 0.12 12.1 0.0 3.5 3 0 0 3 3 3 2 Xylanase inhibitor C-terminal Ku PF02735.16 CDJ41378.1 - 4.9e-20 72.1 0.0 9.6e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 CDJ41378.1 - 4.4e-17 62.4 0.0 6.1e-10 39.3 0.0 2.8 2 1 0 2 2 2 2 Ku C terminal domain like Ku_C PF03730.14 CDJ41378.1 - 0.17 12.6 0.2 0.17 12.6 0.2 2.4 2 1 1 3 3 3 0 Ku70/Ku80 C-terminal arm Glutaredoxin PF00462.24 CDJ41379.1 - 0.0039 17.4 0.0 0.0069 16.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin NSs PF11073.8 CDJ41379.1 - 0.18 11.2 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like DUF1298 PF06974.13 CDJ41380.1 - 1.2e-05 25.3 0.0 0.0064 16.5 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1298) SNF PF00209.18 CDJ41382.1 - 2.5e-18 66.1 39.1 2.5e-18 66.1 33.9 2.1 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family VIT1 PF01988.19 CDJ41383.1 - 1.2e-56 191.9 0.8 1.6e-56 191.6 0.8 1.1 1 0 0 1 1 1 1 VIT family EF-hand_1 PF00036.32 CDJ41384.1 - 3.1e-15 54.5 0.0 0.0056 16.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ41384.1 - 5.2e-15 55.7 0.0 1.6e-06 28.5 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ41384.1 - 1.1e-13 49.9 0.0 0.002 17.9 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CDJ41384.1 - 1.5e-08 33.7 0.1 0.15 11.6 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CDJ41384.1 - 2e-08 34.4 0.0 0.00048 20.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDJ41384.1 - 4.4e-08 32.8 0.2 0.08 12.8 0.1 3.9 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ41384.1 - 0.094 13.0 0.0 12 6.2 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4637 PF15470.6 CDJ41388.1 - 0.00063 19.5 2.1 0.0014 18.4 2.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) Glutaredoxin PF00462.24 CDJ41389.1 - 0.024 14.8 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin XRN_N PF03159.18 CDJ41390.1 - 1.8e-66 224.1 0.0 2.8e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CDJ41390.1 - 2.7e-49 168.3 13.7 1.7e-21 76.8 0.0 3.6 4 0 0 4 4 4 3 Xrn1 helical domain Phostensin_N PF13916.6 CDJ41391.1 - 0.19 12.1 0.3 0.19 12.1 0.3 1.9 1 1 1 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DmpG_comm PF07836.11 CDJ41392.1 - 0.09 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 DmpG-like communication domain DinB_2 PF12867.7 CDJ41392.1 - 3.2 8.3 8.8 0.93 10.0 2.0 2.7 2 1 1 3 3 3 0 DinB superfamily CHCH PF06747.13 CDJ41393.1 - 0.048 13.8 7.4 7.8 6.8 2.9 3.3 1 1 2 3 3 3 0 CHCH domain NDUF_B7 PF05676.13 CDJ41393.1 - 0.37 10.5 4.9 4 7.2 0.9 2.4 1 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 CDJ41393.1 - 4.1 7.5 11.2 3.7 7.6 2.8 2.3 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF2298 PF10060.9 CDJ41394.1 - 2.4 6.8 4.8 1.9 7.1 2.3 2.1 2 0 0 2 2 2 0 Uncharacterized membrane protein (DUF2298) CTD_bind PF04818.13 CDJ41395.1 - 0.065 14.1 0.0 0.34 11.7 0.0 2.3 1 1 0 1 1 1 0 RNA polymerase II-binding domain. OSCP PF00213.18 CDJ41396.1 - 1.8e-22 80.3 5.1 1.8e-22 80.3 5.1 1.4 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit HSL_N PF06350.12 CDJ41396.1 - 0.064 12.2 2.7 0.089 11.8 2.7 1.2 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus SR-25 PF10500.9 CDJ41396.1 - 0.18 11.4 11.5 0.27 10.8 11.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PRR18 PF15671.5 CDJ41396.1 - 0.52 10.2 8.8 0.54 10.1 8.1 1.3 1 1 0 1 1 1 0 Proline-rich protein family 18 DUF2400 PF09674.10 CDJ41396.1 - 0.97 9.4 5.8 0.37 10.7 2.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) CDK2AP PF09806.9 CDJ41396.1 - 1.2 9.2 17.7 1.7 8.7 17.3 1.4 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein Kinesin_assoc PF16183.5 CDJ41396.1 - 5.1 7.2 7.9 2.9e+02 1.5 7.9 2.1 1 1 0 1 1 1 0 Kinesin-associated RAP1 PF07218.11 CDJ41396.1 - 6.8 4.8 6.2 6.7 4.8 6.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LCE6A PF15858.5 CDJ41396.1 - 8.6 7.2 11.4 0.48 11.2 5.3 2.1 3 0 0 3 3 3 0 Late cornified envelope protein 6A family CDK2AP PF09806.9 CDJ41397.1 - 0.024 14.7 5.4 0.039 14.0 5.4 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein D5_N PF08706.11 CDJ41397.1 - 0.079 13.2 1.1 0.11 12.8 1.1 1.1 1 0 0 1 1 1 0 D5 N terminal like TFIIA PF03153.13 CDJ41397.1 - 0.11 12.5 7.2 0.14 12.1 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HI0933_like PF03486.14 CDJ41397.1 - 0.17 10.5 2.2 0.089 11.5 0.4 1.5 2 0 0 2 2 2 0 HI0933-like protein SUV3_C PF12513.8 CDJ41397.1 - 1.3 9.0 5.8 1.2 9.1 0.4 2.4 1 1 1 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal PdaC PF13739.6 CDJ41397.1 - 1.4 10.0 6.5 0.24 12.4 3.1 1.5 2 0 0 2 2 2 0 Deacetylase PdaC DUF3138 PF11336.8 CDJ41397.1 - 7.5 5.0 7.8 9.3 4.7 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Totivirus_coat PF05518.11 CDJ41397.1 - 8 4.4 12.4 11 4.0 12.4 1.1 1 0 0 1 1 1 0 Totivirus coat protein SR-25 PF10500.9 CDJ41398.1 - 6.3e-05 22.7 27.1 6.3e-05 22.7 27.1 9.9 7 4 2 9 9 9 2 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ41398.1 - 8.8e-05 22.7 25.9 8.8e-05 22.7 25.9 4.2 3 1 1 4 4 4 2 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 CDJ41398.1 - 0.0052 17.1 10.1 0.0052 17.1 10.1 5.2 4 1 1 5 5 5 1 Mitochondrial Myo2 receptor-related protein DUF4207 PF13904.6 CDJ41398.1 - 0.0054 16.5 16.5 0.0054 16.5 16.5 5.9 6 2 0 6 6 6 1 Domain of unknown function (DUF4207) Utp14 PF04615.13 CDJ41398.1 - 0.037 12.6 54.2 0.089 11.4 4.3 3.3 3 0 0 3 3 3 0 Utp14 protein Zip PF02535.22 CDJ41398.1 - 0.19 10.9 28.5 0.023 13.9 0.4 4.3 4 0 0 4 4 4 0 ZIP Zinc transporter Caldesmon PF02029.15 CDJ41398.1 - 4 6.1 58.3 0.006 15.4 13.1 3.4 3 0 0 3 3 3 0 Caldesmon Cwf_Cwc_15 PF04889.12 CDJ41398.1 - 4.6 6.9 67.3 0.013 15.3 16.0 4.3 3 1 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein MRP-S28 PF10213.9 CDJ41399.1 - 7.5e-05 23.1 0.0 0.00015 22.2 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF4064 PF13273.6 CDJ41400.1 - 1.3 9.3 0.0 1.3 9.3 0.0 5.8 5 2 0 5 5 5 0 Protein of unknown function (DUF4064) DUF3446 PF11928.8 CDJ41401.1 - 2.6 8.4 8.0 10 6.5 0.7 3.3 3 0 0 3 3 3 0 Early growth response N-terminal domain DEAD PF00270.29 CDJ41402.1 - 4.5e-23 81.9 0.0 1.1e-22 80.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ41402.1 - 1.6e-07 31.7 0.0 4e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SR-25 PF10500.9 CDJ41403.1 - 0.00032 20.4 1.2 0.00062 19.4 1.2 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein ANAPC_CDC26 PF10471.9 CDJ41403.1 - 0.013 16.3 9.9 0.41 11.5 3.4 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF2259 PF10016.9 CDJ41403.1 - 0.019 14.9 1.3 0.42 10.5 1.3 2.3 1 1 0 1 1 1 0 Predicted secreted protein (DUF2259) ATP_bind_3 PF01171.20 CDJ41403.1 - 0.023 14.5 0.8 6.4 6.5 0.0 2.5 2 1 0 2 2 2 0 PP-loop family NINJA_B PF16136.5 CDJ41403.1 - 0.024 15.0 3.3 0.29 11.5 1.6 2.3 2 0 0 2 2 2 0 Putative nuclear localisation signal SUIM_assoc PF16619.5 CDJ41403.1 - 0.028 14.5 3.1 0.028 14.5 3.1 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MITF_TFEB_C_3_N PF15951.5 CDJ41403.1 - 0.03 15.0 7.5 0.04 14.6 1.5 2.4 2 0 0 2 2 2 0 MITF/TFEB/TFEC/TFE3 N-terminus CDK2AP PF09806.9 CDJ41403.1 - 0.15 12.1 9.2 0.27 11.2 9.2 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Dehydrin PF00257.19 CDJ41403.1 - 0.23 12.0 2.5 0.31 11.6 0.8 1.9 2 0 0 2 2 2 0 Dehydrin DUF1635 PF07795.11 CDJ41403.1 - 0.63 9.9 5.0 9.2 6.0 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Ribosomal_60s PF00428.19 CDJ41403.1 - 1.8 9.2 18.8 3 8.5 5.0 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein WD40 PF00400.32 CDJ41404.1 - 0.0013 19.5 0.0 0.0029 18.4 0.0 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat Dehydrin PF00257.19 CDJ41404.1 - 0.046 14.3 3.7 0.099 13.2 3.7 1.5 1 0 0 1 1 1 0 Dehydrin RNase_T PF00929.24 CDJ41406.1 - 1.9e-15 57.8 0.0 3.3e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Exonuclease AP2 PF00847.20 CDJ41407.1 - 4.4e-10 39.6 0.5 1e-09 38.5 0.2 1.7 2 0 0 2 2 2 1 AP2 domain MucB_RseB PF03888.14 CDJ41407.1 - 0.075 12.6 0.1 0.12 11.9 0.1 1.3 1 1 0 1 1 1 0 MucB/RseB N-terminal domain FSA_C PF10479.9 CDJ41409.1 - 2.4 6.2 5.8 4.2 5.4 5.8 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3038 PF11237.8 CDJ41409.1 - 5.1 7.1 13.7 0.16 12.0 3.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3038) Exonuc_VII_L PF02601.15 CDJ41409.1 - 7.1 6.1 19.3 0.33 10.5 13.8 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Presenilin PF01080.17 CDJ41410.1 - 1.5 7.5 5.2 3 6.5 5.2 1.5 1 0 0 1 1 1 0 Presenilin SARAF PF06682.12 CDJ41410.1 - 2 8.0 11.2 0.1 12.3 4.4 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis EF1_GNE PF00736.19 CDJ41411.1 - 0.00012 22.2 0.1 0.00022 21.3 0.1 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain SUIM_assoc PF16619.5 CDJ41411.1 - 0.00015 21.8 24.2 0.0046 17.0 0.8 3.3 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 DUF4407 PF14362.6 CDJ41411.1 - 0.28 10.5 10.2 0.41 10.0 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spt20 PF12090.8 CDJ41411.1 - 0.51 9.9 26.8 0.42 10.2 16.7 2.1 2 0 0 2 2 2 0 Spt20 family DUF3381 PF11861.8 CDJ41411.1 - 0.57 10.0 15.0 0.11 12.3 8.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) TORC_M PF12885.7 CDJ41411.1 - 1.3 9.0 4.5 0.24 11.3 1.2 1.5 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain SPT6_acidic PF14632.6 CDJ41411.1 - 9.2 6.9 13.9 25 5.5 0.1 2.7 2 1 0 2 2 2 0 Acidic N-terminal SPT6 DUF3450 PF11932.8 CDJ41412.1 - 0.05 12.9 15.3 0.093 12.0 15.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3584 PF12128.8 CDJ41412.1 - 0.077 10.5 12.3 0.097 10.2 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 CDJ41412.1 - 1.2 7.9 8.8 1.7 7.4 8.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TFIIA PF03153.13 CDJ41412.1 - 2.1 8.3 16.7 0.37 10.7 12.7 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ41412.1 - 2.6 7.5 10.4 2.6 7.5 8.3 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit EH_Signature PF15611.6 CDJ41412.1 - 6.7 6.0 11.5 6.9 6.0 10.4 1.6 1 1 1 2 2 2 0 EH_Signature domain Utp11 PF03998.13 CDJ41413.1 - 6.8e-09 36.0 34.2 3.9e-08 33.5 34.2 2.2 1 1 0 1 1 1 1 Utp11 protein RskA PF10099.9 CDJ41413.1 - 0.00064 20.1 9.1 0.00064 20.1 9.1 2.7 1 1 1 2 2 2 1 Anti-sigma-K factor rskA DUF2935 PF11155.8 CDJ41413.1 - 0.011 16.1 0.0 0.37 11.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF4179 PF13786.6 CDJ41413.1 - 0.23 11.9 0.1 0.23 11.9 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4179) GREB1 PF15782.5 CDJ41413.1 - 3.1 4.8 17.5 3.8 4.5 17.5 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1690 PF07956.11 CDJ41414.1 - 0.75 10.2 3.9 2.8 8.4 3.9 2.0 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) FAP206 PF12018.8 CDJ41414.1 - 2.2 7.7 4.9 5.1 6.5 4.9 1.6 1 1 0 1 1 1 0 Domain of unknown function DAGAT PF03982.13 CDJ41415.1 - 5.1e-18 65.0 0.0 7e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase SPX PF03105.19 CDJ41415.1 - 0.0062 16.5 3.1 0.0062 16.5 3.1 2.1 1 1 0 2 2 2 1 SPX domain CDC45 PF02724.14 CDJ41415.1 - 0.11 10.7 0.0 0.11 10.7 0.0 2.0 2 0 0 2 2 2 0 CDC45-like protein Presenilin PF01080.17 CDJ41415.1 - 0.6 8.8 0.0 0.6 8.8 0.0 2.8 2 1 0 2 2 2 0 Presenilin Comm PF15957.5 CDJ41415.1 - 0.63 10.4 3.9 0.67 10.3 0.1 2.5 2 0 0 2 2 2 0 Commissureless LUC7 PF03194.15 CDJ41416.1 - 1.9e-38 132.6 1.0 2.3e-38 132.3 1.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Occludin_ELL PF07303.13 CDJ41416.1 - 0.0077 16.9 3.6 0.015 16.0 3.6 1.5 1 1 1 2 2 2 1 Occludin homology domain HSCB_C PF07743.13 CDJ41416.1 - 0.0092 16.5 5.5 0.051 14.1 3.9 2.2 1 1 1 2 2 2 1 HSCB C-terminal oligomerisation domain SKA1 PF07160.12 CDJ41416.1 - 0.023 14.6 2.4 0.029 14.2 2.4 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 FlgN PF05130.12 CDJ41416.1 - 0.025 15.1 3.8 0.7 10.4 0.1 2.1 1 1 1 2 2 2 0 FlgN protein FCD PF07729.12 CDJ41416.1 - 0.031 14.7 1.9 0.074 13.5 0.6 1.9 1 1 1 2 2 2 0 FCD domain DUF2357 PF09823.9 CDJ41416.1 - 0.051 12.8 2.1 0.075 12.3 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) NPV_P10 PF05531.12 CDJ41416.1 - 0.074 13.5 4.7 3.9 8.0 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ran-binding PF05508.11 CDJ41416.1 - 0.078 12.0 1.0 0.11 11.4 1.0 1.2 1 0 0 1 1 1 0 RanGTP-binding protein Exonuc_VII_L PF02601.15 CDJ41416.1 - 0.083 12.5 2.7 0.099 12.2 2.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit IML1 PF12257.8 CDJ41416.1 - 0.15 11.2 0.7 0.56 9.3 0.4 1.8 1 1 1 2 2 2 0 Vacuolar membrane-associated protein Iml1 DASH_Dad4 PF08650.10 CDJ41416.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.6 2 1 0 2 2 2 0 DASH complex subunit Dad4 Meth_synt_2 PF01717.18 CDJ41416.1 - 0.16 11.2 0.6 0.57 9.4 0.6 2.0 1 1 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain DUF1090 PF06476.12 CDJ41416.1 - 0.18 11.9 4.9 0.3 11.2 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) HlyD_2 PF12700.7 CDJ41416.1 - 0.19 10.4 3.5 0.23 10.1 3.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Rho_Binding PF08912.11 CDJ41416.1 - 0.2 12.5 5.2 18 6.2 0.0 2.3 2 0 0 2 2 2 0 Rho Binding ABC_tran_CTD PF16326.5 CDJ41416.1 - 0.25 11.6 5.7 0.25 11.6 3.5 1.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain SlyX PF04102.12 CDJ41416.1 - 0.36 11.5 5.3 24 5.7 3.2 2.5 2 1 0 2 2 2 0 SlyX Mst1_SARAH PF11629.8 CDJ41416.1 - 0.37 10.9 2.9 0.55 10.4 0.5 2.2 1 1 1 2 2 2 0 C terminal SARAH domain of Mst1 ADIP PF11559.8 CDJ41416.1 - 0.39 10.8 8.0 7.9 6.5 8.3 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4404 PF14357.6 CDJ41416.1 - 0.4 11.4 4.4 2.3 8.9 4.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) GIT_CC PF16559.5 CDJ41416.1 - 0.47 10.3 4.3 0.64 9.9 0.0 2.7 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.15 CDJ41416.1 - 0.7 10.0 12.8 9.6 6.4 0.1 3.3 3 0 0 3 3 3 0 Basic region leucine zipper DivIC PF04977.15 CDJ41416.1 - 4.7 7.1 8.2 11 5.8 0.1 2.7 1 1 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 CDJ41416.1 - 9.9 6.7 10.3 2.3 8.7 0.1 2.4 1 1 1 2 2 2 0 Cell division protein ZapB DnaJ-X PF14308.6 CDJ41417.1 - 1.5e-53 181.4 6.0 1.5e-53 181.4 6.0 2.9 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 CDJ41417.1 - 1.5e-24 85.9 1.1 3.4e-24 84.7 1.1 1.7 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.11 CDJ41417.1 - 5.1e-07 30.0 0.0 5.1e-07 30.0 0.0 3.8 3 1 1 4 4 4 1 Autophagy-related protein C terminal domain SelR PF01641.18 CDJ41418.1 - 5.9e-33 113.5 0.3 1.3e-32 112.4 0.3 1.6 1 0 0 1 1 1 1 SelR domain AP2 PF00847.20 CDJ41418.1 - 0.00012 22.3 0.3 0.00039 20.6 0.3 2.0 1 0 0 1 1 1 1 AP2 domain Mitofilin PF09731.9 CDJ41419.1 - 3.9e-11 42.5 0.7 3.9e-11 42.5 0.7 3.4 2 1 1 3 3 3 1 Mitochondrial inner membrane protein SID-1_RNA_chan PF13965.6 CDJ41419.1 - 0.41 9.0 4.5 0.54 8.6 4.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TT_ORF1 PF02956.14 CDJ41419.1 - 1.2 7.7 7.4 1.7 7.2 7.4 1.1 1 0 0 1 1 1 0 TT viral orf 1 VIR_N PF15912.5 CDJ41419.1 - 3.8 7.0 16.1 8.5 5.9 16.1 1.6 1 0 0 1 1 1 0 Virilizer, N-terminal Zip PF02535.22 CDJ41419.1 - 3.9 6.6 14.2 8.4 5.5 14.2 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Otopetrin PF03189.13 CDJ41419.1 - 4.9 5.8 6.7 7.7 5.2 6.7 1.4 1 0 0 1 1 1 0 Otopetrin Cellulose_synt PF03552.14 CDJ41419.1 - 5.4 5.4 7.1 8.5 4.7 7.1 1.2 1 0 0 1 1 1 0 Cellulose synthase CRT10 PF08728.10 CDJ41419.1 - 7.5 4.6 8.4 9.8 4.2 8.4 1.1 1 0 0 1 1 1 0 CRT10 Sortilin-Vps10 PF15902.5 CDJ41421.1 - 2.2e-96 323.4 0.3 1.6e-48 165.6 0.0 2.9 2 1 1 3 3 3 3 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CDJ41421.1 - 1.2e-40 139.7 0.5 2.1e-40 138.9 0.5 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR_2 PF13088.6 CDJ41421.1 - 4.5e-05 22.9 0.0 1.1 8.4 0.0 3.6 3 1 0 3 3 3 2 BNR repeat-like domain BNR PF02012.20 CDJ41421.1 - 0.00019 21.0 20.6 1.2 9.5 0.3 7.5 8 0 0 8 8 8 3 BNR/Asp-box repeat BNR_6 PF15899.5 CDJ41421.1 - 0.27 11.4 0.9 1.2 9.4 0.0 2.7 3 0 0 3 3 3 0 BNR-Asp box repeat MIF PF01187.18 CDJ41422.1 - 4.9e-20 71.9 0.1 5.2e-20 71.9 0.1 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) ADH_zinc_N_2 PF13602.6 CDJ41422.1 - 0.098 13.7 0.0 0.12 13.5 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Tautomerase PF01361.21 CDJ41422.1 - 0.13 12.3 0.0 2.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Tautomerase enzyme AAA_lid_3 PF17862.1 CDJ41422.1 - 0.14 12.0 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA+ lid domain Metallophos PF00149.28 CDJ41423.1 - 4.7e-32 112.1 0.0 7.1e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_2 PF07719.17 CDJ41423.1 - 8.6e-17 59.8 4.8 0.00021 21.2 0.8 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat PPP5 PF08321.12 CDJ41423.1 - 1e-16 61.0 0.0 2.5e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 CDJ41423.1 - 6.7e-16 57.4 4.5 0.00012 21.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ41423.1 - 2.3e-07 31.0 0.5 8.8e-05 22.7 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ41423.1 - 2e-06 27.4 0.4 0.0017 18.0 0.1 3.2 2 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 CDJ41423.1 - 3e-05 23.9 0.9 0.066 13.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ41423.1 - 7.1e-05 22.9 0.3 0.001 19.2 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ41423.1 - 0.00026 21.6 3.9 3.3 8.8 0.0 4.4 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ41423.1 - 0.0065 17.1 5.8 0.21 12.3 0.7 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ41423.1 - 0.026 14.9 1.0 0.51 10.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pex26 PF07163.12 CDJ41423.1 - 0.061 12.6 0.3 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 Pex26 protein TPR_19 PF14559.6 CDJ41423.1 - 6.8 7.3 8.3 33 5.1 1.0 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat Peptidase_M28 PF04389.17 CDJ41424.1 - 4.8e-24 85.1 0.0 2.5e-23 82.8 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M28 AAA_33 PF13671.6 CDJ41425.1 - 2.8e-27 95.6 0.0 5.8e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain SPRY PF00622.28 CDJ41425.1 - 9e-19 67.8 0.0 9e-19 67.8 0.0 2.7 2 1 0 2 2 2 1 SPRY domain AAA_18 PF13238.6 CDJ41425.1 - 0.066 13.8 0.1 0.3 11.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain CK_II_beta PF01214.18 CDJ41426.1 - 1.3e-61 207.6 0.0 2.8e-61 206.5 0.0 1.6 2 0 0 2 2 2 1 Casein kinase II regulatory subunit Radial_spoke PF04712.12 CDJ41426.1 - 0.11 11.4 4.2 0.15 11.0 4.2 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 CDJ41426.1 - 9 4.2 7.5 11 4.0 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi CS PF04969.16 CDJ41427.1 - 3.4e-05 24.8 0.0 6.8e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 CS domain Thioredoxin PF00085.20 CDJ41428.1 - 8.9e-20 70.6 0.4 1e-19 70.4 0.4 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CDJ41428.1 - 0.0041 17.4 0.0 0.0065 16.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like KaiB PF07689.12 CDJ41428.1 - 0.038 13.7 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 KaiB domain PITH PF06201.13 CDJ41429.1 - 1e-22 81.0 0.0 2.8e-21 76.3 0.0 2.0 1 1 0 1 1 1 1 PITH domain Tcf25 PF04910.14 CDJ41430.1 - 4.1e-45 154.4 3.7 6.1e-45 153.8 3.7 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Copine PF07002.16 CDJ41431.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Copine MLVIN_C PF18697.1 CDJ41431.1 - 0.044 13.9 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Glyco_tran_WecB PF03808.13 CDJ41431.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family YliH PF10799.8 CDJ41433.1 - 0.39 10.6 1.7 0.89 9.5 0.0 2.6 2 0 0 2 2 2 0 Biofilm formation protein (YliH/bssR) DUF1072 PF06380.11 CDJ41433.1 - 0.46 10.4 3.9 2.8 7.9 3.9 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) DJ-1_PfpI PF01965.24 CDJ41434.1 - 0.0055 16.5 0.0 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family Thioredoxin_3 PF13192.6 CDJ41434.1 - 0.059 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Methyltr_RsmB-F PF01189.17 CDJ41435.1 - 1.1e-15 57.8 1.8 6.9e-08 32.4 0.1 3.3 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F GTP_EFTU PF00009.27 CDJ41436.1 - 1.9e-54 184.1 0.0 3.2e-54 183.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CDJ41436.1 - 8.9e-31 106.2 0.0 3.8e-30 104.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 CDJ41436.1 - 1.7e-29 101.7 0.0 3.2e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CDJ41436.1 - 1.1e-23 83.1 0.1 2.7e-23 81.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CDJ41436.1 - 1.1e-12 48.1 0.2 2.9e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CDJ41436.1 - 0.0049 16.7 0.0 0.0049 16.7 0.0 1.7 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CDJ41437.1 - 3.7e-13 49.5 0.0 9.1e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ41437.1 - 3.7e-10 39.7 0.0 1.6e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CDJ41437.1 - 3.6e-07 29.8 0.3 0.00026 20.5 0.1 2.5 2 0 0 2 2 2 2 Bacterial TniB protein AAA_16 PF13191.6 CDJ41437.1 - 0.00035 21.0 4.9 0.001 19.5 4.8 1.9 1 1 1 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ41437.1 - 0.00086 19.2 0.2 0.12 12.3 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 CDJ41437.1 - 0.016 14.7 0.0 0.32 10.5 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B Septin PF00735.18 CDJ41437.1 - 0.041 13.1 0.2 0.2 10.9 0.2 2.0 1 1 0 1 1 1 0 Septin MeaB PF03308.16 CDJ41437.1 - 0.12 11.3 0.0 2.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CDJ41437.1 - 0.71 9.9 3.0 6.2 6.9 3.0 2.4 1 1 0 1 1 1 0 Dynamin family ECH_2 PF16113.5 CDJ41438.1 - 2.6e-85 286.9 0.4 2.1e-69 234.6 0.0 2.4 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CDJ41438.1 - 2.4e-23 82.7 0.1 1.4e-22 80.3 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Aconitase_2_N PF06434.13 CDJ41438.1 - 0.062 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus CwsA PF10814.8 CDJ41438.1 - 0.2 11.9 3.1 0.49 10.6 3.1 1.7 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Pro_isomerase PF00160.21 CDJ41439.1 - 1.9e-49 168.0 0.1 6e-49 166.3 0.1 1.9 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CDJ41439.1 - 3e-09 37.4 1.6 0.56 11.2 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-C3HC4_3 PF13920.6 CDJ41440.1 - 1.8e-09 37.3 13.9 2.7e-09 36.7 13.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ41440.1 - 0.0024 18.2 14.0 0.0041 17.4 14.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ41440.1 - 0.097 12.5 14.4 0.19 11.6 14.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 CDJ41440.1 - 0.49 10.1 13.3 1.3 8.7 6.8 2.3 1 1 1 2 2 2 0 P-11 zinc finger EMP24_GP25L PF01105.24 CDJ41441.1 - 3.3e-35 121.7 0.1 4.2e-35 121.3 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HEAT PF02985.22 CDJ41442.1 - 1.7e-05 24.6 16.8 0.037 14.3 0.0 8.3 8 0 0 8 8 8 2 HEAT repeat Importin_rep_6 PF18829.1 CDJ41442.1 - 0.0016 18.6 0.0 0.0044 17.1 0.0 1.7 1 0 0 1 1 1 1 Importin repeat 6 HEAT_2 PF13646.6 CDJ41442.1 - 0.016 15.5 1.2 0.016 15.5 1.2 7.5 6 2 2 8 8 8 0 HEAT repeats Importin_rep_4 PF18808.1 CDJ41442.1 - 0.83 10.0 8.8 11 6.4 0.0 4.7 3 2 1 4 4 4 0 Importin repeat HEAT_EZ PF13513.6 CDJ41442.1 - 3.3 8.3 0.0 3.3 8.3 0.0 9.0 10 1 1 11 11 11 0 HEAT-like repeat DUF4042 PF13251.6 CDJ41442.1 - 3.6 7.2 6.6 2.6 7.7 0.2 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4042) PfkB PF00294.24 CDJ41443.1 - 3e-43 148.3 0.1 3.9e-37 128.2 0.1 2.4 2 1 0 2 2 2 2 pfkB family carbohydrate kinase NAD_Gly3P_dh_N PF01210.23 CDJ41445.1 - 1.5e-41 142.0 0.0 2.5e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CDJ41445.1 - 2.1e-37 128.6 0.0 3.3e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 CDJ41445.1 - 0.12 13.0 0.0 1.2 9.8 0.0 2.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Asp_protease_2 PF13650.6 CDJ41446.1 - 1.7e-07 31.8 0.0 3.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ41446.1 - 2e-06 28.3 0.0 4.2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ41446.1 - 0.00028 20.6 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF3552 PF12072.8 CDJ41446.1 - 0.0068 15.8 0.4 0.011 15.2 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Cyclin PF08613.11 CDJ41447.1 - 3.4e-29 102.3 0.0 5.8e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CDJ41447.1 - 2.8e-11 43.3 0.2 4.1e-11 42.7 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain KH_6 PF15985.5 CDJ41448.1 - 1.3e-10 41.4 0.0 2.7e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 KH domain Adeno_PIX PF03955.14 CDJ41448.1 - 0.069 13.3 0.7 0.069 13.3 0.7 1.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF2183 PF09949.9 CDJ41449.1 - 0.019 15.3 0.0 0.052 13.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) XhlA PF10779.9 CDJ41451.1 - 0.3 11.3 0.0 0.3 11.3 0.0 2.5 3 0 0 3 3 3 0 Haemolysin XhlA HECT PF00632.25 CDJ41452.1 - 4.5e-46 157.7 0.0 7.9e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_5 PF13857.6 CDJ41452.1 - 7.1e-09 35.8 0.3 0.042 14.2 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ41452.1 - 2.6e-08 34.3 0.0 7.8e-07 29.6 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ41452.1 - 2.6e-07 30.8 0.2 0.22 12.1 0.0 4.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CDJ41452.1 - 3.7e-05 24.2 0.1 3.4 8.4 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ41452.1 - 0.00039 20.6 0.5 1.1 10.1 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Exonuc_VII_L PF02601.15 CDJ41452.1 - 0.14 11.7 2.7 0.26 10.8 2.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ribosomal_L5e PF17144.4 CDJ41453.1 - 0.027 14.5 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal large subunit proteins 60S L5, and 50S L18 Spt20 PF12090.8 CDJ41455.1 - 1.1 8.8 53.7 0.27 10.8 11.3 3.1 3 0 0 3 3 3 0 Spt20 family TIP_N PF12457.8 CDJ41455.1 - 1.7 9.1 9.0 6.1 7.3 4.9 2.5 2 1 0 2 2 2 0 Tuftelin interacting protein N terminal PAT1 PF09770.9 CDJ41455.1 - 3.8 5.6 31.3 4.4 5.5 31.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EamA PF00892.20 CDJ41456.1 - 7.5e-11 42.4 17.3 1.7e-10 41.2 17.3 1.6 1 0 0 1 1 1 1 EamA-like transporter family ABC2_membrane PF01061.24 CDJ41457.1 - 1.5e-34 119.3 22.1 1.9e-34 118.9 22.1 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CDJ41457.1 - 2.4e-23 83.1 0.0 8.2e-23 81.4 0.0 1.9 1 1 1 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 CDJ41457.1 - 4.2e-06 26.1 17.0 5.1e-06 25.8 15.6 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CDJ41457.1 - 0.00012 22.0 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 CDJ41457.1 - 0.0035 16.9 0.0 0.0088 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDJ41457.1 - 0.0037 17.0 0.1 0.0099 15.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ41457.1 - 0.0081 16.2 0.2 0.017 15.2 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC2_membrane_2 PF12679.7 CDJ41457.1 - 0.024 13.9 11.1 0.038 13.3 11.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.6 CDJ41457.1 - 0.047 14.2 0.1 0.086 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ41457.1 - 0.076 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 CDJ41457.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Dynamin family AAA_21 PF13304.6 CDJ41457.1 - 0.14 11.9 0.1 7.9 6.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SURF1 PF02104.15 CDJ41459.1 - 7.5e-27 94.7 1.5 1.3e-17 64.6 0.1 2.9 2 2 0 2 2 2 2 SURF1 family EFTUD2 PF16004.5 CDJ41459.1 - 0.81 10.3 7.1 13 6.3 0.0 3.3 3 0 0 3 3 3 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus IPTL-CTERM PF18203.1 CDJ41459.1 - 8.4 6.4 8.8 0.64 10.0 1.4 2.4 2 0 0 2 2 2 0 IPTL-CTERM motif WW PF00397.26 CDJ41460.1 - 5.5e-07 29.6 1.3 1.2e-06 28.5 1.3 1.6 1 0 0 1 1 1 1 WW domain PepSY_TM_like_2 PF16357.5 CDJ41460.1 - 1.1 9.2 3.1 1.9 8.4 0.4 2.6 2 0 0 2 2 2 0 Putative PepSY_TM-like DegT_DnrJ_EryC1 PF01041.17 CDJ41462.1 - 9.3e-17 61.4 0.0 1.8e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Dynein_C PF18199.1 CDJ41463.1 - 5.5e-70 236.0 0.0 7.4e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 CDJ41463.1 - 6.8e-38 129.4 0.0 1.4e-37 128.4 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 CDJ41463.1 - 8.1e-35 120.1 0.0 2.1e-34 118.7 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_9 PF12781.7 CDJ41464.1 - 9.2e-24 83.8 0.6 1.3e-23 83.3 0.6 1.2 1 0 0 1 1 1 1 ATP-binding dynein motor region SesA PF17107.5 CDJ41464.1 - 0.051 13.8 0.2 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases LcrV PF04792.12 CDJ41464.1 - 0.054 12.8 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 V antigen (LcrV) protein MT PF12777.7 CDJ41465.1 - 9.8e-43 146.5 4.8 1.3e-42 146.1 4.8 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 CDJ41465.1 - 8.9e-23 80.9 0.0 3.6e-19 69.1 0.0 2.5 1 1 1 2 2 2 2 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDJ41465.1 - 2.1e-20 72.8 3.1 1.4e-19 70.1 0.0 2.9 3 0 0 3 3 3 1 ATP-binding dynein motor region Spc7 PF08317.11 CDJ41465.1 - 0.00047 19.1 5.1 0.00047 19.1 5.1 2.3 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF745 PF05335.13 CDJ41465.1 - 0.0017 18.1 15.2 0.0036 17.0 1.9 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF745) DHR10 PF18595.1 CDJ41465.1 - 0.0074 16.3 5.2 0.0074 16.3 5.2 2.9 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain HAUS-augmin3 PF14932.6 CDJ41465.1 - 0.023 14.3 0.8 0.023 14.3 0.8 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Sec8_exocyst PF04048.14 CDJ41465.1 - 0.027 14.4 7.9 0.23 11.4 0.1 3.8 2 2 2 4 4 4 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 CDJ41465.1 - 0.1 12.6 5.9 2.1 8.4 0.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 CDJ41465.1 - 0.12 12.3 3.2 0.45 10.4 0.3 2.7 2 0 0 2 2 2 0 Sec34-like family PMEI PF04043.15 CDJ41465.1 - 0.12 12.7 5.4 3.5 7.9 0.3 2.8 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor DASH_Spc34 PF08657.10 CDJ41465.1 - 0.18 11.6 3.9 1.3 8.8 0.2 2.3 2 0 0 2 2 2 0 DASH complex subunit Spc34 Plk4_PB2 PF18409.1 CDJ41465.1 - 0.18 12.5 3.4 0.2 12.4 0.2 2.6 2 1 1 3 3 2 0 Polo-like Kinase 4 Polo Box 2 MPS2 PF17060.5 CDJ41465.1 - 0.26 10.5 6.5 0.28 10.4 0.5 2.2 2 0 0 2 2 2 0 Monopolar spindle protein 2 ATG16 PF08614.11 CDJ41465.1 - 0.27 11.4 14.0 0.021 15.0 3.3 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 CDJ41465.1 - 0.29 11.2 9.2 0.12 12.5 2.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 CDJ41465.1 - 0.44 10.7 3.2 0.97 9.6 0.3 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 CDJ41465.1 - 0.53 9.8 15.7 0.18 11.3 3.1 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit TelA PF05816.11 CDJ41465.1 - 0.67 9.0 11.1 3 6.8 1.4 2.5 2 1 0 2 2 2 0 Toxic anion resistance protein (TelA) AcylCoA_dehyd_C PF12186.8 CDJ41465.1 - 0.74 10.0 4.3 2.6 8.2 0.4 3.1 4 0 0 4 4 2 0 Acyl-CoA dehydrogenase C terminal FliD_N PF02465.18 CDJ41465.1 - 0.75 10.5 5.4 7.5 7.3 0.3 2.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4795 PF16043.5 CDJ41465.1 - 0.81 9.3 13.4 0.5 9.9 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Phage_GP20 PF06810.11 CDJ41465.1 - 0.88 9.4 13.9 1.6 8.5 2.5 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 BST2 PF16716.5 CDJ41465.1 - 1.2 9.8 12.0 0.71 10.5 3.4 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 ERM PF00769.19 CDJ41465.1 - 1.4 8.7 20.7 3.2 7.5 7.7 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family TMF_TATA_bd PF12325.8 CDJ41465.1 - 2 8.7 11.2 0.37 11.0 1.9 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HrpB7 PF09486.10 CDJ41465.1 - 2.1 8.7 16.8 0.065 13.6 4.2 3.0 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) PCRF PF03462.18 CDJ41465.1 - 2.6 7.9 13.8 0.9 9.4 2.9 3.1 2 1 1 3 3 3 0 PCRF domain V_ATPase_I PF01496.19 CDJ41465.1 - 2.6 5.8 5.4 1.5 6.6 0.3 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.12 CDJ41465.1 - 2.9 7.9 11.0 0.5 10.4 1.0 2.9 2 1 1 3 3 3 0 Laminin Domain II DivIVA PF05103.13 CDJ41465.1 - 3.1 7.9 15.4 3.8 7.6 3.4 3.2 2 1 1 3 3 3 0 DivIVA protein KxDL PF10241.9 CDJ41465.1 - 3.5 8.0 5.8 5 7.5 0.4 3.4 2 1 1 3 3 3 0 Uncharacterized conserved protein Tropomyosin_1 PF12718.7 CDJ41465.1 - 4.7 7.4 18.2 0.055 13.6 5.8 2.5 2 0 0 2 2 2 0 Tropomyosin like Phage_GPO PF05929.11 CDJ41465.1 - 4.8 6.7 8.5 4.4 6.8 0.8 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Fez1 PF06818.15 CDJ41465.1 - 6.7 7.1 13.8 0.97 9.8 2.4 2.4 2 0 0 2 2 2 0 Fez1 CorA PF01544.18 CDJ41465.1 - 7.8 5.7 7.7 0.41 9.9 0.3 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein ZapB PF06005.12 CDJ41465.1 - 9.5 6.8 13.0 0.076 13.5 2.5 2.6 2 1 0 2 2 1 0 Cell division protein ZapB AAA_7 PF12775.7 CDJ41466.1 - 3.4e-38 131.0 0.0 5e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_1 PF17857.1 CDJ41466.1 - 9.4e-13 48.2 0.1 2.4e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDJ41466.1 - 0.00017 22.1 0.2 0.00038 20.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CDJ41466.1 - 0.00025 21.1 0.0 0.00057 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDJ41466.1 - 0.0007 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain TIP49 PF06068.13 CDJ41466.1 - 0.0092 15.2 0.0 0.025 13.8 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain Imm48 PF15574.6 CDJ41466.1 - 0.021 14.6 0.0 6 6.7 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 48 AAA PF00004.29 CDJ41466.1 - 0.042 14.3 0.0 0.087 13.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CDJ41466.1 - 0.063 13.2 0.2 0.21 11.5 0.2 1.9 1 1 0 1 1 1 0 NACHT domain AAA_lid_8 PF17868.1 CDJ41466.1 - 0.11 12.4 0.3 0.36 10.8 0.2 1.9 2 0 0 2 2 2 0 AAA lid domain Mg_chelatase PF01078.21 CDJ41466.1 - 0.11 11.8 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 CDJ41466.1 - 0.27 11.0 0.9 0.4 10.4 0.2 1.6 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 CDJ41467.1 - 1.4e-49 168.8 0.1 1e-48 166.0 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 CDJ41467.1 - 6.1e-10 39.2 0.0 0.00016 21.7 0.0 2.4 1 1 1 2 2 2 2 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 CDJ41467.1 - 0.00023 20.8 0.0 0.0024 17.6 0.0 2.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CDJ41467.1 - 0.00097 19.7 0.0 0.0018 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ41467.1 - 0.004 17.6 0.1 0.0097 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CDJ41467.1 - 0.008 15.8 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CDJ41467.1 - 0.0086 16.1 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Mg_chelatase PF01078.21 CDJ41467.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CDJ41467.1 - 0.032 14.5 0.0 0.083 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ41467.1 - 0.04 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase L27 PF02828.16 CDJ41467.1 - 0.046 13.5 0.3 0.12 12.2 0.3 1.7 1 0 0 1 1 1 0 L27 domain AAA_33 PF13671.6 CDJ41467.1 - 0.046 13.9 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDJ41467.1 - 0.047 14.1 0.0 0.087 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 CDJ41467.1 - 0.17 11.8 0.2 0.6 10.0 0.1 2.1 2 1 0 2 2 2 0 NACHT domain Rad17 PF03215.15 CDJ41467.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 CDJ41467.1 - 0.18 11.5 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DHC_N2 PF08393.13 CDJ41468.1 - 1.6e-56 192.2 2.3 1.7e-56 192.1 0.8 1.7 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 CDJ41468.1 - 1.9e-16 60.0 0.4 3.1e-16 59.3 0.4 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ41469.1 - 2.8e-15 56.4 0.2 2.8e-15 56.4 0.2 3.0 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 BCL9 PF11502.8 CDJ41469.1 - 0.076 12.8 0.1 0.3 10.9 0.2 2.0 2 0 0 2 2 2 0 B-cell lymphoma 9 protein DegS PF05384.11 CDJ41469.1 - 0.15 11.5 8.1 0.047 13.2 2.2 2.9 3 0 0 3 3 3 0 Sensor protein DegS Exonuc_VII_L PF02601.15 CDJ41470.1 - 0.14 11.7 5.2 0.18 11.3 5.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_A17 PF05380.13 CDJ41470.1 - 0.56 10.2 6.9 1.2 9.2 1.9 2.5 1 1 1 2 2 2 0 Pao retrotransposon peptidase MeaB PF03308.16 CDJ41470.1 - 0.78 8.7 5.0 1.1 8.2 5.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2362 PF10154.9 CDJ41470.1 - 1.9 7.3 12.7 2.7 6.9 12.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Retrotrans_gag PF03732.17 CDJ41470.1 - 3.8 7.8 12.8 2.1 8.7 9.1 2.3 2 1 1 3 3 3 0 Retrotransposon gag protein DUF883 PF05957.13 CDJ41470.1 - 9.4 6.9 9.4 21 5.8 0.7 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) UCH PF00443.29 CDJ41471.1 - 3.2e-44 151.4 0.0 9e-44 149.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CDJ41471.1 - 1.5e-11 44.5 0.0 7.3e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 CDJ41471.1 - 2.5e-10 40.0 2.0 0.00012 21.9 0.1 3.2 3 0 0 3 3 3 2 UBA/TS-N domain UCH_1 PF13423.6 CDJ41471.1 - 4.5e-10 39.6 0.1 0.00013 21.7 0.5 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RuvA_C PF07499.13 CDJ41471.1 - 0.0024 18.3 0.3 0.53 10.8 0.2 3.1 2 0 0 2 2 2 1 RuvA, C-terminal domain zf-UBP_var PF17807.1 CDJ41471.1 - 0.0033 17.1 0.0 0.0077 16.0 0.0 1.7 1 0 0 1 1 1 1 Variant UBP zinc finger Dis3l2_C_term PF17877.1 CDJ41471.1 - 0.039 14.3 0.2 0.15 12.4 0.2 2.0 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal Eapp_C PF10238.9 CDJ41471.1 - 2.7 8.0 14.0 0.15 12.1 0.6 4.1 5 0 0 5 5 5 0 E2F-associated phosphoprotein SRP14 PF02290.15 CDJ41472.1 - 1.5e-17 63.7 0.8 7e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle 14kD protein DUF4387 PF14330.6 CDJ41472.1 - 0.13 13.0 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4387) Presenilin PF01080.17 CDJ41472.1 - 0.97 8.1 5.0 1 8.1 5.0 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ41472.1 - 1.2 8.7 12.1 1.4 8.5 12.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ41472.1 - 2.6 9.0 5.4 4.7 8.2 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Cpn60_TCP1 PF00118.24 CDJ41474.1 - 4.9e-135 450.9 5.5 5.7e-135 450.7 5.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chromo PF00385.24 CDJ41475.1 - 0.0021 17.9 0.0 0.0044 16.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CDJ41476.1 - 0.056 13.6 0.1 0.088 13.0 0.1 1.2 1 0 0 1 1 1 0 Integrase core domain SLBP_RNA_bind PF15247.6 CDJ41477.1 - 2.1e-23 82.2 1.3 4e-23 81.3 1.3 1.5 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain TFIIA PF03153.13 CDJ41477.1 - 0.25 11.3 6.1 0.5 10.3 6.0 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit P5CR_dimer PF14748.6 CDJ41478.1 - 2.2e-23 82.5 0.2 8e-22 77.5 0.2 2.2 2 0 0 2 2 2 2 Pyrroline-5-carboxylate reductase dimerisation MutL_C PF08676.11 CDJ41479.1 - 8.3e-14 51.6 0.0 2.7e-10 40.2 0.0 3.7 4 0 0 4 4 4 2 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CDJ41479.1 - 2e-12 46.8 0.0 3.4e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 CDJ41479.1 - 4.3e-08 33.6 0.0 9.6e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDJ41479.1 - 9.6e-07 28.7 0.0 1.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LtuB PF17455.2 CDJ41479.1 - 0.048 14.3 0.4 4.3 8.0 0.1 3.2 2 1 1 3 3 3 0 Late transcription unit B TPR_1 PF00515.28 CDJ41480.1 - 7.8e-09 35.0 9.8 0.00031 20.4 1.6 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ41480.1 - 2.2e-08 33.6 8.4 0.00043 20.2 2.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ41480.1 - 5.1e-07 29.3 2.9 5.1e-07 29.3 2.9 2.6 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 CDJ41480.1 - 1.1e-06 28.6 7.1 1.1e-06 28.6 7.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ41480.1 - 0.00031 21.3 11.9 0.00031 21.3 11.9 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ41480.1 - 0.0011 19.0 4.0 0.81 10.1 0.7 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ41480.1 - 0.0018 18.9 4.2 0.0018 18.9 4.2 5.2 6 1 1 7 7 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ41480.1 - 0.011 15.7 3.0 0.34 11.0 0.3 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF2478 PF10649.9 CDJ41480.1 - 0.05 13.2 0.4 1.6 8.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) PAS_4 PF08448.10 CDJ41480.1 - 0.11 12.7 0.1 1.6 9.0 0.0 2.6 2 0 0 2 2 2 0 PAS fold DUF2510 PF10708.9 CDJ41480.1 - 0.2 11.4 1.0 0.66 9.8 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) TPR_7 PF13176.6 CDJ41480.1 - 0.22 11.7 5.4 1 9.6 0.8 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ41480.1 - 0.32 11.3 8.0 1.5 9.2 8.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ41480.1 - 5.6 7.6 8.0 1.4 9.5 1.7 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ECH_2 PF16113.5 CDJ41481.1 - 2.4e-35 122.6 0.0 1.3e-31 110.3 0.0 2.2 1 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CDJ41481.1 - 2.7e-07 30.2 0.0 6.3e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RNA_pol_Rpb4 PF03874.16 CDJ41481.1 - 0.11 12.8 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb4 RPAP3_C PF13877.6 CDJ41481.1 - 0.13 12.9 0.2 5.7 7.6 0.1 2.4 1 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 SNF2_N PF00176.23 CDJ41482.1 - 2.7e-45 154.6 0.0 4.3e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ41482.1 - 4.4e-13 49.6 0.0 1.1e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ41482.1 - 2.5e-07 30.8 0.0 6.2e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ41482.1 - 0.00035 20.4 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 CDJ41482.1 - 0.0025 17.1 0.0 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 CDJ41482.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase HDA2-3 PF11496.8 CDJ41482.1 - 0.021 14.0 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 COG2 PF06148.11 CDJ41486.1 - 7.2 6.7 5.5 16 5.6 0.5 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 LUD_dom PF02589.15 CDJ41487.1 - 1.4 8.6 5.3 1.1 8.9 0.1 3.3 4 0 0 4 4 4 0 LUD domain BPL_LplA_LipB PF03099.19 CDJ41489.1 - 2.8e-09 37.0 0.5 5.5e-09 36.0 0.5 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 CDJ41489.1 - 5.5e-05 23.0 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain DNA_pol_lambd_f PF10391.9 CDJ41489.1 - 0.36 10.7 3.7 9.3 6.2 0.2 2.7 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Lipid_DES PF08557.10 CDJ41489.1 - 0.55 9.8 2.4 25 4.5 0.2 2.7 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) Macoilin PF09726.9 CDJ41490.1 - 0.15 10.6 21.4 0.32 9.5 21.4 1.5 1 0 0 1 1 1 0 Macoilin family DUF4520 PF15016.6 CDJ41493.1 - 0.06 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) NYN_YacP PF05991.11 CDJ41493.1 - 0.06 13.3 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 YacP-like NYN domain Ist1 PF03398.14 CDJ41494.1 - 1.5e-31 109.5 0.7 2e-31 109.1 0.7 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Chorein_N PF12624.7 CDJ41495.1 - 2.6e-29 101.7 0.6 8.8e-29 100.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CDJ41495.1 - 7.3e-14 52.1 0.0 2.1e-11 44.1 0.0 2.8 2 0 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 CDJ41495.1 - 5.1e-06 26.1 0.0 1.7e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 CDJ41495.1 - 3.1e-05 24.2 0.0 0.00021 21.6 0.0 2.5 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 CDJ41495.1 - 0.053 13.3 2.5 18 5.0 0.0 3.4 3 0 0 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal RAP1 PF07218.11 CDJ41495.1 - 6.3 5.0 15.9 12 4.0 15.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Abhydrolase_3 PF07859.13 CDJ41496.1 - 2.3e-35 122.4 0.0 4.1e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CDJ41496.1 - 5.2e-08 32.2 0.1 1.9e-07 30.4 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 CDJ41496.1 - 4.2e-05 22.6 0.0 6.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 CDJ41496.1 - 0.0017 17.8 0.0 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Coleoptericin PF06286.11 CDJ41496.1 - 0.03 14.4 0.2 0.058 13.5 0.2 1.4 1 0 0 1 1 1 0 Coleoptericin Nop52 PF05997.12 CDJ41497.1 - 2.1e-39 135.6 0.2 3.2e-39 135.0 0.2 1.3 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Evr1_Alr PF04777.13 CDJ41499.1 - 4.3e-11 43.2 0.2 1.4e-10 41.5 0.1 1.8 2 0 0 2 2 2 1 Erv1 / Alr family BT1 PF03092.16 CDJ41500.1 - 2.8e-68 230.4 26.1 1.9e-40 138.6 14.3 2.1 1 1 1 2 2 2 2 BT1 family MFS_1 PF07690.16 CDJ41500.1 - 3.7e-12 45.9 37.3 9.4e-07 28.1 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CDJ41500.1 - 0.00063 18.7 13.1 0.0012 17.8 13.1 1.4 1 0 0 1 1 1 1 MFS_1 like family AFP PF02420.15 CDJ41501.1 - 0.29 11.6 1.4 0.91 10.1 1.4 1.9 1 0 0 1 1 1 0 Insect antifreeze protein repeat Neur_chan_memb PF02932.16 CDJ41501.1 - 7.4 6.6 8.0 4.1 7.4 5.6 1.8 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region OTU PF02338.19 CDJ41502.1 - 0.00026 21.5 0.0 0.0014 19.1 0.0 2.0 1 1 0 1 1 1 1 OTU-like cysteine protease TFIIA PF03153.13 CDJ41502.1 - 1.1 9.1 11.1 1.5 8.7 11.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PseudoU_synth_2 PF00849.22 CDJ41503.1 - 2e-20 73.5 0.0 2e-20 73.5 0.0 2.2 2 0 0 2 2 2 1 RNA pseudouridylate synthase NARP1 PF12569.8 CDJ41504.1 - 8e-103 345.1 26.1 4.8e-78 263.3 15.9 4.0 4 0 0 4 4 4 3 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 CDJ41504.1 - 2.1e-11 43.1 11.1 4.2e-05 23.2 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ41504.1 - 6e-11 41.9 2.5 0.025 14.9 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ41504.1 - 4.6e-07 30.4 11.6 0.023 15.3 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ41504.1 - 7.2e-06 25.7 0.0 3.3e-05 23.7 0.0 9.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ41504.1 - 2.2e-05 24.3 19.8 0.0013 18.7 0.0 6.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ41504.1 - 4e-05 24.1 15.5 0.6 11.1 0.0 8.7 7 3 2 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ41504.1 - 9.3e-05 22.5 4.9 3.4 7.9 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ41504.1 - 0.00015 21.3 3.4 0.15 11.8 0.1 3.9 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.6 CDJ41504.1 - 0.00075 19.4 9.3 0.094 12.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ41504.1 - 0.0014 18.9 13.2 0.39 11.0 0.0 5.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ41504.1 - 0.006 17.1 12.3 0.037 14.5 0.1 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat Adaptin_binding PF10199.9 CDJ41504.1 - 0.009 16.6 0.0 0.52 10.9 0.0 2.9 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 TPR_6 PF13174.6 CDJ41504.1 - 0.01 16.4 12.9 19 6.1 0.0 7.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ41504.1 - 0.044 13.7 0.4 2.2 8.3 0.0 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Laminin_G_2 PF02210.24 CDJ41505.1 - 0.00018 22.1 0.0 0.11 13.0 0.0 2.5 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 CDJ41505.1 - 0.0078 16.4 0.0 3.6 7.8 0.0 2.4 2 0 0 2 2 2 2 Laminin G domain DUF1080 PF06439.11 CDJ41505.1 - 0.016 15.4 0.0 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1080) HdeA PF06411.11 CDJ41507.1 - 0.028 14.6 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 HdeA/HdeB family COMP PF11598.8 CDJ41507.1 - 0.065 13.7 0.3 0.14 12.7 0.3 1.5 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Ricin_B_lectin PF00652.22 CDJ41508.1 - 9.7e-08 32.3 0.3 0.0085 16.4 0.0 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain F5_F8_type_C PF00754.25 CDJ41508.1 - 7.1e-07 29.4 0.7 1.7e-06 28.1 0.1 2.0 2 0 0 2 2 2 1 F5/8 type C domain RNA_pol_3_Rpc31 PF11705.8 CDJ41509.1 - 8.1e-06 26.3 10.4 7.8e-05 23.0 10.4 2.2 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 FYDLN_acid PF09538.10 CDJ41509.1 - 5.7 7.7 10.7 18 6.1 10.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) MAS20 PF02064.15 CDJ41510.1 - 0.11 12.6 3.8 0.053 13.6 1.6 1.5 2 0 0 2 2 2 0 MAS20 protein import receptor AMP-binding PF00501.28 CDJ41511.1 - 1.7e-82 277.3 0.1 1.8e-79 267.4 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ41511.1 - 5.6e-23 81.7 0.5 1.3e-22 80.6 0.5 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CDJ41511.1 - 4.8e-16 58.4 1.5 1e-15 57.3 1.5 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus E1-E2_ATPase PF00122.20 CDJ41512.1 - 2.9e-35 121.4 3.8 6.6e-35 120.3 0.1 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CDJ41512.1 - 1.5e-34 119.3 1.7 1.5e-34 119.3 1.7 3.8 5 0 0 5 5 5 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CDJ41512.1 - 9.8e-17 61.9 0.8 1.2e-09 38.7 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ41512.1 - 3.4e-14 52.7 0.0 6.7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CDJ41512.1 - 1.1e-07 31.4 0.0 4.4e-07 29.5 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDJ41512.1 - 0.00017 21.4 2.3 0.0018 18.1 0.4 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PAP_central PF04928.17 CDJ41512.1 - 0.12 11.3 0.1 0.26 10.2 0.1 1.5 1 0 0 1 1 1 0 Poly(A) polymerase central domain HPP PF04982.13 CDJ41512.1 - 8.3 6.6 15.4 0.055 13.7 2.5 3.7 3 1 0 3 3 3 0 HPP family MMtag PF10159.9 CDJ41513.1 - 5.6e-17 61.8 1.9 5.6e-17 61.8 1.9 4.0 4 0 0 4 4 4 1 Multiple myeloma tumor-associated FUSC_2 PF13515.6 CDJ41514.1 - 1e-11 45.0 7.9 1e-11 45.0 7.9 3.6 3 1 1 4 4 4 2 Fusaric acid resistance protein-like SesA PF17107.5 CDJ41514.1 - 0.17 12.1 1.1 11 6.3 0.0 3.8 4 0 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases F-box-like PF12937.7 CDJ41516.1 - 0.0039 17.0 0.3 0.019 14.8 0.3 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ41516.1 - 0.007 16.2 0.1 0.056 13.3 0.0 2.6 3 0 0 3 3 3 1 F-box domain WD40 PF00400.32 CDJ41516.1 - 0.016 16.1 4.9 0.96 10.4 0.2 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat PRTase_2 PF15609.6 CDJ41516.1 - 0.029 13.9 0.2 0.086 12.3 0.2 1.7 1 0 0 1 1 1 0 Phosphoribosyl transferase NolV PF06635.12 CDJ41517.1 - 0.063 12.7 1.1 0.14 11.6 1.1 1.5 1 0 0 1 1 1 0 Nodulation protein NolV STT3 PF02516.14 CDJ41518.1 - 7.9e-09 35.0 0.2 8.5e-09 34.8 0.2 1.0 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit STT3 PF02516.14 CDJ41519.1 - 1.9e-33 116.1 13.4 2.3e-33 115.9 13.4 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit BT1 PF03092.16 CDJ41520.1 - 7e-07 27.9 3.5 0.0011 17.3 0.1 2.4 2 0 0 2 2 2 2 BT1 family RepB_primase PF16793.5 CDJ41520.1 - 0.11 12.6 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 RepB DNA-primase from phage plasmid Comm PF15957.5 CDJ41520.1 - 0.15 12.4 0.1 0.4 11.0 0.1 1.7 1 0 0 1 1 1 0 Commissureless Peptidase_M24_C PF16188.5 CDJ41520.1 - 0.16 12.0 1.6 31 4.7 0.0 3.7 4 0 0 4 4 4 0 C-terminal region of peptidase_M24 Mt_ATP-synt_B PF05405.14 CDJ41520.1 - 0.17 11.5 2.9 0.32 10.6 2.9 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Remorin_C PF03763.13 CDJ41520.1 - 0.28 11.1 1.7 0.58 10.0 1.7 1.5 1 0 0 1 1 1 0 Remorin, C-terminal region SPATA1_C PF15743.5 CDJ41520.1 - 1.2 9.2 5.9 2.2 8.4 5.9 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus zf-CDGSH PF09360.10 CDJ41521.1 - 6.5e-08 32.7 0.1 6.5e-08 32.7 0.1 1.8 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type MMR_HSR1 PF01926.23 CDJ41522.1 - 1.8e-17 63.5 0.0 7.7e-15 55.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ41522.1 - 4.8e-06 26.6 0.1 0.0045 16.9 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CDJ41522.1 - 9.1e-05 22.0 0.0 0.00043 19.8 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ41522.1 - 0.014 15.4 1.2 0.014 15.4 1.2 3.8 4 0 0 4 4 4 0 Dynamin family Roc PF08477.13 CDJ41522.1 - 0.12 12.6 0.0 13 6.0 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CDJ41522.1 - 0.14 11.7 0.0 10 5.7 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zip PF02535.22 CDJ41522.1 - 0.4 9.8 18.9 0.038 13.2 1.2 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Apt1 PF10351.9 CDJ41523.1 - 0.85 8.4 6.5 1 8.1 6.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ41523.1 - 8 6.3 13.2 11 5.8 13.2 1.2 1 0 0 1 1 1 0 SPX domain Rep_fac-A_3 PF08661.11 CDJ41524.1 - 0.00014 22.1 0.0 0.0002 21.7 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 Ribosomal_L1 PF00687.21 CDJ41525.1 - 0.00017 21.4 0.0 0.00042 20.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family RPA_interact_M PF14767.6 CDJ41525.1 - 0.68 10.5 6.9 1.6 9.3 0.6 2.3 2 0 0 2 2 2 0 Replication protein A interacting middle His_Phos_1 PF00300.22 CDJ41526.1 - 1.2e-05 25.1 2.9 0.94 9.1 0.1 3.9 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) SUIM_assoc PF16619.5 CDJ41526.1 - 0.056 13.5 12.7 0.34 11.0 0.6 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 BROMI PF14961.6 CDJ41526.1 - 0.17 9.3 0.0 0.25 8.7 0.0 1.1 1 0 0 1 1 1 0 Broad-minded protein His_Phos_1 PF00300.22 CDJ41527.1 - 1.2e-11 44.7 0.0 7.1e-06 25.8 0.0 2.8 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 CDJ41528.1 - 0.00085 19.1 0.2 0.44 10.2 0.0 3.1 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF1639 PF07797.14 CDJ41528.1 - 0.65 10.0 2.7 1.5 8.8 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) His_Phos_1 PF00300.22 CDJ41529.1 - 0.031 14.0 0.8 2.7 7.6 0.0 3.1 2 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) SPC22 PF04573.12 CDJ41530.1 - 4.1e-42 143.6 0.0 5.1e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase subunit LSM PF01423.22 CDJ41531.1 - 7.7e-16 57.5 0.1 1.1e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CDJ41531.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Hfq protein SOG2 PF10428.9 CDJ41533.1 - 0.043 13.0 17.2 0.051 12.8 17.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 CDJ41533.1 - 0.31 8.1 5.1 0.35 7.9 5.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF966 PF06136.13 CDJ41533.1 - 2.2 7.9 10.1 3.1 7.4 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Apt1 PF10351.9 CDJ41533.1 - 6.7 5.4 9.7 0.26 10.1 4.3 1.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain UCH PF00443.29 CDJ41534.1 - 2e-35 122.5 0.0 2.7e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CDJ41534.1 - 1.5e-05 24.7 0.0 7.3e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family TBK1_ULD PF18396.1 CDJ41534.1 - 0.00057 19.8 0.0 0.0014 18.5 0.0 1.6 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain UCH_1 PF13423.6 CDJ41534.1 - 0.0035 17.0 0.0 0.07 12.7 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.6 CDJ41534.1 - 0.11 12.9 0.0 1.1 9.8 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain SGP PF17228.2 CDJ41535.1 - 0.027 15.3 14.7 0.027 15.3 14.7 6.9 3 1 2 5 5 5 0 Sulphur globule protein DUF615 PF04751.14 CDJ41536.1 - 0.00051 20.1 2.1 0.00078 19.5 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF615) V-ATPase_C PF03223.15 CDJ41536.1 - 0.058 12.8 0.3 0.079 12.3 0.3 1.1 1 0 0 1 1 1 0 V-ATPase subunit C Njmu-R1 PF15053.6 CDJ41536.1 - 0.16 11.1 0.2 0.21 10.7 0.2 1.1 1 0 0 1 1 1 0 Mjmu-R1-like protein family Fib_alpha PF08702.10 CDJ41536.1 - 0.3 11.3 1.0 0.48 10.6 1.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GTP_cyclohydroI PF01227.22 CDJ41536.1 - 1.1 8.7 3.5 0.45 9.9 0.7 1.7 2 0 0 2 2 2 0 GTP cyclohydrolase I DUF536 PF04394.14 CDJ41537.1 - 1.5 8.7 5.1 8 6.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF536 FTA2 PF13095.6 CDJ41539.1 - 0.038 13.6 0.1 0.055 13.1 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Utp21 PF04192.12 CDJ41540.1 - 7.5e-15 55.1 0.5 7.5e-15 55.1 0.5 1.4 2 0 0 2 2 2 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 CDJ41540.1 - 6e-05 23.3 0.0 0.014 15.6 0.0 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ41540.1 - 6.8e-05 23.6 1.8 0.054 14.4 0.1 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Frtz PF11768.8 CDJ41540.1 - 0.022 13.1 0.0 0.032 12.6 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 CDJ41540.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RskA PF10099.9 CDJ41540.1 - 0.24 11.7 7.6 8.4 6.6 4.6 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ41540.1 - 1.1 8.8 11.9 2.4 7.7 2.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TOM20_plant PF06552.12 CDJ41541.1 - 0.085 12.6 0.2 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 RBFA PF02033.18 CDJ41542.1 - 2.2e-12 47.4 0.0 4.6e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Ribosome-binding factor A ACT PF01842.25 CDJ41542.1 - 0.096 12.5 0.0 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 ACT domain NIF PF03031.18 CDJ41543.1 - 1.7e-12 47.4 0.0 1.2e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Apt1 PF10351.9 CDJ41543.1 - 0.1 11.5 0.8 0.13 11.1 0.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain TPR_1 PF00515.28 CDJ41544.1 - 2.5e-11 42.9 0.3 3.6e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ41544.1 - 8.1e-11 41.2 0.1 3.8e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ41544.1 - 2.7e-09 36.5 0.0 0.0024 18.0 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ41544.1 - 5e-08 33.0 0.1 0.00048 20.2 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ41544.1 - 1.3e-06 28.0 0.1 1.8e-05 24.3 0.0 2.1 1 1 1 2 2 2 1 TPR repeat TPR_16 PF13432.6 CDJ41544.1 - 3.1e-05 24.5 0.0 4.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ41544.1 - 0.0001 22.8 0.2 0.01 16.6 0.0 2.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ41544.1 - 0.00097 19.6 0.0 0.0019 18.6 0.0 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 CDJ41544.1 - 0.005 16.3 0.1 0.9 9.0 0.0 2.4 2 0 0 2 2 2 1 SHNi-TPR MAS20 PF02064.15 CDJ41544.1 - 0.0067 16.5 0.1 0.0099 16.0 0.1 1.3 1 0 0 1 1 1 1 MAS20 protein import receptor TPR_12 PF13424.6 CDJ41544.1 - 0.0089 16.3 0.1 0.077 13.3 0.1 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ41544.1 - 0.025 14.4 0.0 8.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 CDJ41544.1 - 0.067 13.3 0.3 0.24 11.5 0.3 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) Cas_Cas02710 PF09670.10 CDJ41544.1 - 0.08 11.7 0.1 0.08 11.7 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) TPR_7 PF13176.6 CDJ41544.1 - 0.091 12.8 0.0 0.79 9.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RAP PF08373.10 CDJ41545.1 - 1.8e-13 50.4 0.0 3.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 RAP domain Spc29 PF17082.5 CDJ41545.1 - 0.35 10.7 1.9 0.52 10.1 1.9 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 PAP1 PF08601.10 CDJ41546.1 - 1.5 8.5 14.9 1.6 8.3 14.9 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 FAP PF07174.11 CDJ41546.1 - 2.6 7.4 18.0 2.9 7.3 18.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Gcd10p PF04189.13 CDJ41547.1 - 1.9e-09 37.0 0.0 3.1e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family SRC-1 PF08832.10 CDJ41548.1 - 4.2 8.5 17.6 0.85 10.7 5.1 3.4 2 1 1 3 3 3 0 Steroid receptor coactivator Hid1 PF12722.7 CDJ41548.1 - 6.2 4.8 16.8 8.2 4.4 16.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Archease PF01951.16 CDJ41549.1 - 5.2e-23 81.8 13.6 1.4e-10 41.5 10.6 2.5 1 1 1 2 2 2 2 Archease protein family (MTH1598/TM1083) SARAF PF06682.12 CDJ41549.1 - 0.0066 16.1 3.2 0.0066 16.1 3.2 2.0 1 1 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis OAD_gamma PF04277.13 CDJ41549.1 - 0.019 15.6 4.6 0.8 10.3 1.1 3.1 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF4667 PF15700.5 CDJ41549.1 - 0.019 15.1 1.5 0.019 15.1 1.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4667) Ribosomal_60s PF00428.19 CDJ41549.1 - 0.031 14.9 10.0 1.2 9.8 9.4 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ41549.1 - 0.11 12.7 21.4 0.48 10.7 21.4 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Rad4 PF03835.15 CDJ41549.1 - 0.21 11.3 5.5 0.53 10.0 5.5 1.7 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain Tsg PF04668.12 CDJ41549.1 - 0.25 12.0 4.4 1 10.0 0.3 2.3 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region Presenilin PF01080.17 CDJ41549.1 - 0.27 10.0 10.3 0.044 12.5 6.1 1.7 2 0 0 2 2 2 0 Presenilin EphA2_TM PF14575.6 CDJ41549.1 - 0.29 12.0 2.8 6.2 7.8 0.4 2.9 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain ALMT PF11744.8 CDJ41549.1 - 0.34 9.7 4.4 0.48 9.2 4.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter O-antigen_lig PF13425.6 CDJ41549.1 - 0.37 9.5 0.9 0.47 9.2 0.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4484 PF14831.6 CDJ41549.1 - 0.86 9.6 10.9 2.9 7.9 10.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) CNDH2_N PF06278.11 CDJ41549.1 - 0.96 9.7 11.1 0.49 10.6 1.5 3.0 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Zip PF02535.22 CDJ41549.1 - 1 8.5 5.8 0.54 9.4 4.0 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter DUF4366 PF14283.6 CDJ41549.1 - 1 9.4 9.4 0.82 9.7 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) SID-1_RNA_chan PF13965.6 CDJ41549.1 - 1.1 7.6 3.9 1.4 7.2 3.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4288 PF14119.6 CDJ41549.1 - 1.2 9.6 11.2 6.3 7.3 3.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) MecA PF05389.12 CDJ41549.1 - 1.3 8.6 10.6 2.9 7.5 3.8 2.3 2 1 0 2 2 2 0 Negative regulator of genetic competence (MecA) RAP1 PF07218.11 CDJ41549.1 - 1.5 7.1 6.7 2 6.6 6.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Mss4 PF04421.13 CDJ41549.1 - 1.6 8.9 6.2 2.9 8.1 0.3 2.3 2 0 0 2 2 2 0 Mss4 protein DUF2489 PF10675.9 CDJ41549.1 - 1.8 8.5 18.9 3.7 7.5 3.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Conotoxin PF02950.17 CDJ41549.1 - 1.9 9.6 13.5 0.13 13.3 2.5 2.8 3 0 0 3 3 2 0 Conotoxin 7tm_7 PF08395.12 CDJ41549.1 - 2.3 7.4 7.6 2.1 7.5 0.4 2.0 2 0 0 2 2 2 0 7tm Chemosensory receptor IHABP4_N PF16174.5 CDJ41549.1 - 3.9 8.1 21.2 11 6.6 0.5 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF2722 PF10846.8 CDJ41550.1 - 4.6e-05 22.6 19.1 0.0012 17.8 9.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ41550.1 - 0.00035 20.3 13.3 0.00035 20.3 13.3 2.3 2 0 0 2 2 2 2 Spt20 family RskA PF10099.9 CDJ41550.1 - 0.022 15.1 1.4 0.022 15.1 1.4 4.7 1 1 2 3 3 3 0 Anti-sigma-K factor rskA SpoIIP PF07454.11 CDJ41550.1 - 1.7 8.1 11.5 0.64 9.4 1.8 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) zinc_ribbon_6 PF14599.6 CDJ41550.1 - 3.1 7.9 6.9 0.94 9.5 2.9 2.2 1 1 1 2 2 2 0 Zinc-ribbon MCU PF04678.13 CDJ41550.1 - 4.1 7.5 7.6 4.4 7.4 2.6 2.5 2 0 0 2 2 2 0 Mitochondrial calcium uniporter MecA PF05389.12 CDJ41550.1 - 4.8 6.7 8.1 0.82 9.3 0.4 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) TERB2 PF15101.6 CDJ41550.1 - 5.7 6.9 17.4 0.49 10.4 4.4 2.6 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Peptidase_S49_N PF08496.10 CDJ41550.1 - 7.3 6.6 10.8 1.2 9.2 1.4 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal eIF-3_zeta PF05091.12 CDJ41550.1 - 9.1 5.1 16.6 0.4 9.6 3.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TetR_C_28 PF17937.1 CDJ41552.1 - 0.0076 16.7 1.0 0.027 14.9 0.4 2.2 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain IBN_N PF03810.19 CDJ41552.1 - 0.031 14.2 0.1 0.031 14.2 0.1 1.6 2 0 0 2 2 2 0 Importin-beta N-terminal domain SQHop_cyclase_N PF13249.6 CDJ41552.1 - 0.044 12.9 0.6 0.089 11.9 0.1 1.7 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain ROS_MUCR PF05443.11 CDJ41552.1 - 0.049 13.7 0.4 0.076 13.1 0.4 1.3 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein SQHop_cyclase_C PF13243.6 CDJ41552.1 - 0.078 12.1 3.9 1.1 8.3 0.2 2.0 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain DUF812 PF05667.11 CDJ41553.1 - 0.012 14.5 38.0 0.016 14.1 38.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ATP11 PF06644.11 CDJ41553.1 - 0.086 12.6 28.7 0.027 14.3 20.4 2.2 2 0 0 2 2 2 0 ATP11 protein Exonuc_VII_L PF02601.15 CDJ41553.1 - 0.96 8.9 45.3 0.05 13.2 31.2 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit BORG_CEP PF14957.6 CDJ41553.1 - 2.8 9.1 20.0 3.1 9.0 13.4 2.3 2 0 0 2 2 2 0 Cdc42 effector TCP PF03634.13 CDJ41553.1 - 6.6 7.3 28.2 12 6.4 0.4 2.3 2 0 0 2 2 2 0 TCP family transcription factor PA26 PF04636.13 CDJ41553.1 - 8.3 5.2 26.7 0.57 9.1 15.4 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Sod_Fe_C PF02777.18 CDJ41554.1 - 7.6e-33 112.7 3.3 2.3e-32 111.2 0.1 2.4 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CDJ41554.1 - 4.1e-28 97.7 4.0 6.4e-28 97.1 2.8 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain MPM1 PF17234.2 CDJ41554.1 - 0.2 11.9 6.2 0.79 10.0 4.0 2.5 1 1 1 2 2 2 0 Mitochondrial peculiar membrane protein 1 Ribosomal_60s PF00428.19 CDJ41555.1 - 0.033 14.8 10.2 0.055 14.1 10.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Auxin_canalis PF05703.11 CDJ41555.1 - 0.075 13.0 16.0 0.087 12.7 16.0 1.1 1 0 0 1 1 1 0 Auxin canalisation DUF1980 PF09323.10 CDJ41555.1 - 0.56 10.1 6.0 0.71 9.8 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) TFIIA PF03153.13 CDJ41555.1 - 1.5 8.7 22.6 1.9 8.4 22.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tristanin_u2 PF16638.5 CDJ41555.1 - 2.8 8.8 7.8 3.8 8.3 7.8 1.2 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers DUF2870 PF11069.8 CDJ41555.1 - 5.2 7.5 9.7 70 3.9 9.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) YlzJ PF14035.6 CDJ41555.1 - 5.5 7.3 11.3 2.2 8.5 1.7 2.5 1 1 1 2 2 2 0 YlzJ-like protein Presenilin PF01080.17 CDJ41555.1 - 7.6 5.2 10.1 7.9 5.1 10.1 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ41555.1 - 9.9 6.1 8.0 11 6.0 8.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Clat_adaptor_s PF01217.20 CDJ41557.1 - 4.8e-24 84.9 0.2 6.1e-24 84.6 0.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF677 PF05055.12 CDJ41557.1 - 1.8 7.4 10.1 2.4 7.0 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) SIT PF15330.6 CDJ41558.1 - 4.8 7.7 0.0 4.8 7.7 0.0 3.6 2 1 2 4 4 4 0 SHP2-interacting transmembrane adaptor protein, SIT PDEase_I PF00233.19 CDJ41559.1 - 4.3e-20 72.4 0.5 3.4e-15 56.4 0.8 2.4 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CDJ41559.1 - 0.024 14.9 0.1 0.057 13.6 0.1 1.6 1 0 0 1 1 1 0 HD domain Prefoldin PF02996.17 CDJ41560.1 - 1.3e-20 73.5 0.4 1.9e-20 73.0 0.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit RecG_N PF17190.4 CDJ41560.1 - 0.031 15.0 0.3 0.38 11.5 0.0 2.1 2 0 0 2 2 2 0 RecG N-terminal helical domain DUF4530 PF15039.6 CDJ41560.1 - 0.049 13.8 0.1 0.097 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) TPR_2 PF07719.17 CDJ41561.1 - 0.00057 19.8 1.7 2 8.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_5 PF12688.7 CDJ41561.1 - 0.012 15.9 4.6 0.015 15.5 0.9 2.6 2 0 0 2 2 2 0 Tetratrico peptide repeat Cloacin PF03515.14 CDJ41561.1 - 0.058 13.1 0.4 0.1 12.3 0.4 1.2 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain SET PF00856.28 CDJ41561.1 - 0.49 10.8 5.5 0.08 13.3 0.5 2.4 2 0 0 2 2 2 0 SET domain DUF3626 PF12294.8 CDJ41562.1 - 0.0014 17.7 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3626) tRNA-synt_His PF13393.6 CDJ41563.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF3626 PF12294.8 CDJ41564.1 - 2.4e-15 56.4 0.1 2.8e-12 46.3 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3626) Pkinase PF00069.25 CDJ41565.1 - 3.7e-25 88.8 0.0 4.6e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ41565.1 - 3.6e-16 59.2 0.0 4.6e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ41565.1 - 3.9e-08 32.5 0.0 5.3e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CDJ41565.1 - 0.082 11.9 0.6 0.15 11.0 0.1 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase GST_C_3 PF14497.6 CDJ41568.1 - 0.023 14.9 0.0 0.13 12.4 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF5486 PF17588.2 CDJ41569.1 - 0.63 10.0 3.0 0.95 9.4 3.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5486) SUIM_assoc PF16619.5 CDJ41570.1 - 0.63 10.2 8.1 0.19 11.8 3.5 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AP2 PF00847.20 CDJ41571.1 - 0.051 13.8 1.5 0.11 12.7 1.5 1.5 1 0 0 1 1 1 0 AP2 domain NAD_binding_10 PF13460.6 CDJ41572.1 - 0.19 11.6 3.8 0.5 10.2 3.8 1.6 1 0 0 1 1 1 0 NAD(P)H-binding DPM3 PF08285.11 CDJ41574.1 - 6.1 7.1 6.9 0.65 10.2 0.2 2.8 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) GPS2_interact PF15784.5 CDJ41576.1 - 0.0067 16.8 2.4 0.0067 16.8 2.4 3.1 3 1 1 4 4 4 1 G-protein pathway suppressor 2-interacting domain IQ PF00612.27 CDJ41576.1 - 0.0099 15.6 0.0 0.036 13.8 0.0 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif PI_PP_I PF18363.1 CDJ41576.1 - 0.27 11.4 2.5 1.8 8.8 1.1 2.6 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain SPX PF03105.19 CDJ41576.1 - 0.35 10.7 19.7 0.12 12.3 16.6 1.7 2 0 0 2 2 2 0 SPX domain DUF1492 PF07374.11 CDJ41576.1 - 1.1 9.4 5.1 0.58 10.4 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1492) Hydantoinase_B PF02538.14 CDJ41576.1 - 1.2 7.5 5.2 2 6.7 5.2 1.3 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase DUF4618 PF15397.6 CDJ41576.1 - 2.7 7.3 29.8 0.68 9.3 8.2 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.12 CDJ41576.1 - 8.6 6.9 14.1 2.9 8.4 0.6 4.3 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein RT_RNaseH PF17917.1 CDJ41579.1 - 8.7e-24 83.8 0.0 1.4e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ41579.1 - 2.2e-16 59.7 0.0 5.3e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ41579.1 - 4.7e-08 33.0 0.2 8.7e-08 32.2 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_3 PF13456.6 CDJ41579.1 - 0.0013 18.6 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like zf-H2C2 PF09337.10 CDJ41579.1 - 0.081 13.2 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Dpy-30 PF05186.13 CDJ41580.1 - 2e-05 24.2 0.0 4.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Dpy-30 motif PPTA PF01239.22 CDJ41580.1 - 0.2 11.4 0.6 1.5 8.7 0.5 2.3 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Neuregulin PF02158.15 CDJ41580.1 - 3.1 7.0 14.4 1.7 7.9 12.8 1.4 1 1 0 1 1 1 0 Neuregulin intracellular region Trypsin_2 PF13365.6 CDJ41581.1 - 5.5e-17 63.1 0.2 1.1e-16 62.1 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 CDJ41581.1 - 3.8e-09 36.2 1.1 8.5e-09 35.1 1.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ41581.1 - 5.5e-07 29.8 0.0 1.3e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ41581.1 - 8.9e-05 22.7 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Peptidase_S29 PF02907.15 CDJ41581.1 - 0.0046 16.7 0.2 0.01 15.6 0.2 1.5 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Trypsin PF00089.26 CDJ41581.1 - 0.017 14.9 0.0 0.048 13.5 0.0 1.7 1 1 0 1 1 1 0 Trypsin Tricorn_PDZ PF14685.6 CDJ41581.1 - 0.054 13.5 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain DUF3601 PF12208.8 CDJ41581.1 - 0.22 11.7 0.0 0.45 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) Phage_AlpA PF05930.12 CDJ41582.1 - 0.04 13.7 0.0 0.94 9.3 0.0 2.3 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) Calreticulin PF00262.18 CDJ41583.1 - 6.5e-33 114.1 0.0 1.4e-31 109.6 0.0 2.1 2 0 0 2 2 2 2 Calreticulin family Cullin_Nedd8 PF10557.9 CDJ41584.1 - 3.4e-10 39.8 0.0 6.8e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 CDJ41584.1 - 0.14 12.6 0.0 1.2 9.5 0.0 2.4 1 1 0 1 1 1 0 Penicillinase repressor Dynein_C PF18199.1 CDJ41587.1 - 1.3e-104 349.7 0.0 2.6e-104 348.7 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CDJ41587.1 - 1.2e-81 273.1 0.1 5e-81 271.0 0.1 2.0 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 CDJ41587.1 - 4.4e-54 182.7 0.0 1.1e-53 181.4 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ41587.1 - 1.9e-49 166.7 0.0 4.1e-46 155.9 0.0 2.7 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain bZIP_1 PF00170.21 CDJ41587.1 - 0.075 13.1 1.1 0.16 12.1 1.1 1.6 1 0 0 1 1 1 0 bZIP transcription factor MnmE_helical PF12631.7 CDJ41587.1 - 0.15 12.2 0.8 9.2 6.4 4.5 1.6 1 1 0 1 1 1 0 MnmE helical domain MT PF12777.7 CDJ41588.1 - 6e-29 101.2 6.9 7.9e-29 100.7 6.9 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor TMF_TATA_bd PF12325.8 CDJ41588.1 - 0.059 13.6 10.0 1.3 9.3 1.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding AAA_6 PF12774.7 CDJ41589.1 - 1.4e-147 490.9 1.8 5.4e-147 489.0 0.1 2.7 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 CDJ41589.1 - 1.9e-92 309.3 0.3 4.3e-91 304.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CDJ41589.1 - 2.3e-79 265.1 0.0 1.3e-72 243.2 0.0 3.5 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_5 PF07728.14 CDJ41589.1 - 2.5e-28 98.8 0.0 4.3e-09 36.5 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDJ41589.1 - 7.1e-25 87.6 0.3 6.9e-24 84.4 0.0 2.8 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ41589.1 - 4.5e-21 74.9 0.0 1.6e-20 73.2 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CDJ41589.1 - 2.9e-12 47.2 0.0 0.0069 16.8 0.0 4.7 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ41589.1 - 3.9e-09 37.1 3.9 0.31 11.4 0.0 6.2 7 1 1 8 8 6 2 AAA ATPase domain AAA_22 PF13401.6 CDJ41589.1 - 1.8e-08 34.7 2.2 0.22 11.8 0.0 5.0 6 0 0 6 6 4 3 AAA domain DUF853 PF05872.12 CDJ41589.1 - 1.8e-06 26.9 0.3 0.3 9.6 0.0 3.2 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) AAA_18 PF13238.6 CDJ41589.1 - 3e-06 27.8 0.0 0.076 13.6 0.0 4.3 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 CDJ41589.1 - 1.3e-05 25.5 0.0 0.13 12.7 0.0 4.2 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 CDJ41589.1 - 5.3e-05 23.0 0.2 1 9.1 0.1 3.5 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 CDJ41589.1 - 0.00012 22.4 0.1 2.9 8.1 0.0 4.7 5 0 0 5 5 5 1 AAA domain Mg_chelatase PF01078.21 CDJ41589.1 - 0.0003 20.2 0.9 3.5 7.0 0.0 4.2 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 CDJ41589.1 - 0.00039 19.6 3.0 0.91 8.5 0.0 4.0 4 0 0 4 4 4 2 Type II/IV secretion system protein SRP54 PF00448.22 CDJ41589.1 - 0.001 18.7 0.8 1.3 8.6 0.0 3.7 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 CDJ41589.1 - 0.0014 18.3 5.6 7.2 6.1 0.1 4.5 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.6 CDJ41589.1 - 0.0019 18.4 0.3 16 5.7 0.0 4.4 5 0 0 5 5 4 0 AAA domain DEAD PF00270.29 CDJ41589.1 - 0.0028 17.5 0.0 2.4 7.9 0.0 3.3 3 1 0 3 3 3 1 DEAD/DEAH box helicase Sigma54_activat PF00158.26 CDJ41589.1 - 0.0036 17.0 1.8 17 5.1 0.0 3.9 5 0 0 5 5 3 0 Sigma-54 interaction domain TsaE PF02367.17 CDJ41589.1 - 0.0036 17.3 1.3 6.1 6.9 0.2 3.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 CDJ41589.1 - 0.0038 17.3 0.2 11 6.0 0.0 3.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 CDJ41589.1 - 0.0048 16.7 0.1 7.6 6.2 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_19 PF13245.6 CDJ41589.1 - 0.0051 17.2 1.4 15 5.9 0.3 4.1 4 1 0 4 4 3 0 AAA domain AAA_11 PF13086.6 CDJ41589.1 - 0.07 12.9 0.1 8 6.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CDJ41589.1 - 0.071 12.4 0.6 6.1 6.1 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin AAA_2 PF07724.14 CDJ41589.1 - 0.081 13.0 0.0 2.7 8.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 CDJ41589.1 - 0.092 12.7 0.1 9.2 6.1 0.0 3.5 3 0 0 3 3 3 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 CDJ41589.1 - 0.15 11.8 0.6 1.4 8.6 0.0 2.9 3 0 0 3 3 3 0 Cytidylate kinase AAA_24 PF13479.6 CDJ41589.1 - 0.19 11.4 0.2 34 4.1 0.0 3.7 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 CDJ41589.1 - 0.21 11.5 0.9 35 4.3 0.0 3.7 3 1 0 3 3 3 0 NACHT domain Sec2p PF06428.11 CDJ41589.1 - 0.66 10.0 5.5 0.28 11.2 1.7 2.3 2 0 0 2 2 1 0 GDP/GTP exchange factor Sec2p DHC_N2 PF08393.13 CDJ41590.1 - 8.1e-66 222.7 7.0 1.6e-41 142.8 0.6 2.6 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 2 SNAPc_SNAP43 PF09808.9 CDJ41591.1 - 0.0096 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Peptidase_M4_C PF02868.15 CDJ41593.1 - 0.031 14.1 0.2 0.054 13.4 0.0 1.5 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain Ins_allergen_rp PF06757.13 CDJ41594.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification Lin-8 PF03353.15 CDJ41594.1 - 0.06 12.9 0.1 0.086 12.4 0.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist APC_u14 PF16635.5 CDJ41594.1 - 0.11 13.1 0.2 0.21 12.2 0.2 1.4 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr Trp_oprn_chp PF09534.10 CDJ41596.1 - 0.00082 19.2 9.7 0.00098 19.0 9.7 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Trep_Strep PF09605.10 CDJ41596.1 - 0.0025 17.8 0.8 0.0033 17.4 0.8 1.1 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) LapA_dom PF06305.11 CDJ41596.1 - 0.031 14.1 0.6 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Pox_A14 PF05767.12 CDJ41596.1 - 0.046 13.9 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 RskA PF10099.9 CDJ41596.1 - 0.053 13.8 18.7 0.03 14.6 14.5 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF4064 PF13273.6 CDJ41596.1 - 0.087 13.1 0.1 0.19 12.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4834 PF16118.5 CDJ41596.1 - 0.22 12.5 1.6 2 9.4 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ41597.1 - 0.077 13.0 12.0 0.095 12.7 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ41597.1 - 0.33 10.5 4.1 0.44 10.1 4.1 1.2 1 0 0 1 1 1 0 Spt20 family SRP-alpha_N PF04086.13 CDJ41597.1 - 1.2 9.0 10.2 1.3 8.9 10.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FAM199X PF15814.5 CDJ41597.1 - 4.9 6.1 9.2 0.3 10.1 3.6 1.7 1 1 1 2 2 2 0 Protein family FAM199X Abhydrolase_1 PF00561.20 CDJ41598.1 - 0.27 10.8 1.8 0.38 10.3 1.8 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Spt20 PF12090.8 CDJ41598.1 - 0.3 10.7 23.7 0.32 10.6 13.5 2.1 2 0 0 2 2 2 0 Spt20 family Ldt_C PF17969.1 CDJ41598.1 - 6.5 7.6 5.8 1.2 9.9 1.4 1.9 2 0 0 2 2 2 0 L,D-transpeptidase C-terminal domain DUF4834 PF16118.5 CDJ41598.1 - 9.2 7.3 6.8 21 6.2 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SNF2_N PF00176.23 CDJ41600.1 - 1.7e-11 43.4 0.1 4.9e-11 42.0 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF2439 PF10382.9 CDJ41600.1 - 0.0079 16.5 0.1 0.015 15.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) SUIM_assoc PF16619.5 CDJ41600.1 - 0.01 15.9 0.3 0.01 15.9 0.3 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2330 PF10092.9 CDJ41600.1 - 0.072 12.2 0.4 0.15 11.1 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) Velvet PF11754.8 CDJ41600.1 - 0.13 12.2 5.5 0.032 14.2 1.6 1.8 2 0 0 2 2 2 0 Velvet factor SAPS PF04499.15 CDJ41600.1 - 0.18 10.5 0.4 0.26 10.0 0.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Lin-8 PF03353.15 CDJ41600.1 - 0.99 8.9 5.8 0.39 10.2 3.4 1.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ41600.1 - 1.3 8.9 19.4 0.033 14.2 11.8 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3292 PF11696.8 CDJ41600.1 - 3.6 5.8 9.3 5.8 5.2 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) SAGA-Tad1 PF12767.7 CDJ41600.1 - 5.4 6.7 7.3 0.39 10.4 2.3 1.6 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit ABC1 PF03109.16 CDJ41604.1 - 5.8e-08 32.9 0.0 1.4e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 ABC1 family RRN3 PF05327.11 CDJ41604.1 - 0.054 12.0 0.0 0.076 11.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.13 CDJ41604.1 - 0.2 11.6 6.6 0.038 14.0 1.4 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 CDJ41604.1 - 0.42 9.7 7.2 0.69 9.0 7.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 CDJ41604.1 - 2 8.0 6.3 3 7.4 6.3 1.2 1 0 0 1 1 1 0 Spt20 family MutL_C PF08676.11 CDJ41606.1 - 0.025 14.4 0.5 0.035 13.9 0.5 1.3 1 0 0 1 1 1 0 MutL C terminal dimerisation domain IHABP4_N PF16174.5 CDJ41606.1 - 0.51 10.9 8.9 0.65 10.6 8.9 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal TFIIA PF03153.13 CDJ41606.1 - 2 8.3 9.7 2.3 8.1 9.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3318 PF11780.8 CDJ41606.1 - 4.6 7.2 12.2 3 7.8 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3318) SUIM_assoc PF16619.5 CDJ41606.1 - 4.9 7.3 17.9 7.7 6.7 8.4 2.5 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 CDJ41607.1 - 0.00028 21.4 3.0 0.00041 20.9 3.0 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Menin PF05053.13 CDJ41607.1 - 0.021 13.2 0.1 0.023 13.1 0.1 1.0 1 0 0 1 1 1 0 Menin EF-hand_7 PF13499.6 CDJ41608.1 - 0.024 15.1 0.0 0.067 13.6 0.0 1.7 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 CDJ41608.1 - 0.13 12.3 0.0 0.87 9.7 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain eRF1_1 PF03463.15 CDJ41608.1 - 0.13 12.2 1.0 0.27 11.3 0.2 1.8 1 1 1 2 2 2 0 eRF1 domain 1 DUF755 PF05501.11 CDJ41608.1 - 3.9 7.8 40.7 0.62 10.3 6.5 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF755) RIFIN PF02009.16 CDJ41608.1 - 4.8 7.0 8.8 6.3 6.6 8.8 1.2 1 0 0 1 1 1 0 Rifin DUF572 PF04502.13 CDJ41608.1 - 5.8 6.4 12.8 8.2 5.9 12.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pkinase PF00069.25 CDJ41609.1 - 9.1e-52 176.0 0.0 1.4e-51 175.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ41609.1 - 6.4e-19 68.2 0.0 1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2722 PF10846.8 CDJ41609.1 - 2.8e-05 23.3 1.5 3e-05 23.2 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pkinase_fungal PF17667.1 CDJ41609.1 - 0.00024 20.0 2.6 0.0007 18.5 2.6 1.6 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ41609.1 - 0.0016 17.8 0.0 0.0016 17.8 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ41609.1 - 0.13 12.2 7.4 0.34 10.8 7.4 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family SpoIIP PF07454.11 CDJ41609.1 - 0.14 11.5 5.2 0.23 10.9 5.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Suf PF05843.14 CDJ41609.1 - 0.61 10.0 6.9 0.86 9.5 6.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM199X PF15814.5 CDJ41609.1 - 3.5 6.6 6.8 5.2 6.0 6.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X TFIIA PF03153.13 CDJ41609.1 - 6 6.7 18.4 9 6.2 18.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit XRN_M PF17846.1 CDJ41610.1 - 0.46 9.4 26.3 0.25 10.2 13.7 2.2 2 0 0 2 2 2 0 Xrn1 helical domain DUF3446 PF11928.8 CDJ41610.1 - 6.7 7.1 20.9 2.6 8.4 5.6 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain Fumble PF03630.14 CDJ41610.1 - 8 5.5 7.3 12 5.0 5.3 2.2 2 0 0 2 2 2 0 Fumble SR-25 PF10500.9 CDJ41611.1 - 0.00022 20.9 16.6 0.00027 20.7 16.6 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TP2 PF01254.18 CDJ41611.1 - 0.015 15.9 4.1 0.02 15.5 4.1 1.1 1 0 0 1 1 1 0 Nuclear transition protein 2 IMUP PF15761.5 CDJ41611.1 - 0.017 15.8 16.4 0.027 15.2 16.4 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein AF-4 PF05110.13 CDJ41611.1 - 0.025 12.7 16.3 0.03 12.5 16.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein YL1 PF05764.13 CDJ41611.1 - 0.064 13.4 15.4 0.08 13.0 15.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 CDJ41611.1 - 0.19 10.0 14.5 0.22 9.8 14.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 CDJ41611.1 - 0.29 10.5 17.3 0.33 10.3 17.3 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SIR4_SID PF16991.5 CDJ41611.1 - 0.76 9.8 6.3 0.82 9.7 6.3 1.1 1 0 0 1 1 1 0 Sir4 SID domain XAP5 PF04921.14 CDJ41611.1 - 2.4 7.9 10.5 3.6 7.3 10.5 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator FAM199X PF15814.5 CDJ41611.1 - 5 6.1 15.0 5.6 5.9 15.0 1.1 1 0 0 1 1 1 0 Protein family FAM199X Hamartin PF04388.12 CDJ41611.1 - 5.4 5.6 9.1 6.3 5.3 9.1 1.0 1 0 0 1 1 1 0 Hamartin protein Menin PF05053.13 CDJ41611.1 - 5.7 5.2 14.9 6.6 5.0 14.9 1.0 1 0 0 1 1 1 0 Menin SR-25 PF10500.9 CDJ41612.1 - 9.3e-06 25.4 36.6 1.4e-05 24.9 36.6 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ41612.1 - 0.3 11.4 18.2 0.085 13.1 6.2 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA CDC45 PF02724.14 CDJ41612.1 - 4.1 5.6 15.3 4.4 5.5 15.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PAT1 PF09770.9 CDJ41612.1 - 5.2 5.2 19.0 5.8 5.1 19.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Menin PF05053.13 CDJ41612.1 - 5.6 5.2 17.1 6.3 5.0 17.1 1.3 1 0 0 1 1 1 0 Menin RAP1 PF07218.11 CDJ41612.1 - 7.8 4.6 29.6 9.7 4.3 29.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ASD2 PF08687.11 CDJ41612.1 - 8.4 5.9 15.4 9.8 5.6 15.4 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Yippee-Mis18 PF03226.14 CDJ41613.1 - 1.2e-13 51.2 0.2 1.5e-13 50.8 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_6 PF14599.6 CDJ41613.1 - 0.012 15.6 0.2 0.012 15.6 0.2 2.2 2 0 0 2 2 2 0 Zinc-ribbon zf-P11 PF03854.14 CDJ41613.1 - 0.014 15.0 1.0 0.03 14.0 1.0 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-CHY PF05495.12 CDJ41613.1 - 0.027 14.9 6.5 0.14 12.7 6.5 1.9 1 1 0 1 1 1 0 CHY zinc finger RIG-I_C-RD PF11648.8 CDJ41613.1 - 0.034 14.4 0.3 0.051 13.8 0.3 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I HNH_5 PF14279.6 CDJ41613.1 - 0.043 13.7 0.7 6.1 6.8 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease DUF2321 PF10083.9 CDJ41613.1 - 0.064 12.9 0.5 0.097 12.3 0.5 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Ribosomal_L40e PF01020.17 CDJ41613.1 - 0.14 12.1 3.3 0.4 10.6 1.8 2.4 2 1 1 3 3 3 0 Ribosomal L40e family Zn_ribbon_SprT PF17283.2 CDJ41613.1 - 0.22 11.5 5.1 0.17 11.8 1.4 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DZR PF12773.7 CDJ41613.1 - 0.63 10.1 4.2 7 6.8 0.2 2.2 1 1 0 1 1 1 0 Double zinc ribbon CAF1 PF04857.20 CDJ41614.1 - 0.081 12.1 3.5 0.11 11.6 3.5 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Exonuc_VII_L PF02601.15 CDJ41614.1 - 0.19 11.2 9.8 0.28 10.7 9.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ALMT PF11744.8 CDJ41614.1 - 1.6 7.5 10.7 2.3 7.0 10.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter EPL1 PF10513.9 CDJ41614.1 - 2.1 8.7 9.9 4.6 7.6 9.9 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like UPF0061 PF02696.14 CDJ41614.1 - 2.7 6.7 10.3 3.6 6.2 10.3 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family CPSF100_C PF13299.6 CDJ41614.1 - 3.1 8.0 7.0 6.6 6.9 7.0 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal N6_N4_Mtase PF01555.18 CDJ41614.1 - 4.3 7.0 5.6 24 4.5 6.6 1.5 1 1 0 1 1 1 0 DNA methylase LMBR1 PF04791.16 CDJ41614.1 - 5.7 5.7 5.2 8.1 5.2 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Bul1_N PF04425.12 CDJ41614.1 - 6.1 5.5 9.7 8.8 5.0 9.7 1.1 1 0 0 1 1 1 0 Bul1 N terminus DUF4865 PF16157.5 CDJ41614.1 - 6.5 6.7 9.2 14 5.6 9.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4865) Glycos_transf_2 PF00535.26 CDJ41616.1 - 1.9e-21 76.6 0.0 3.3e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ41616.1 - 8e-16 58.5 5.1 3.7e-10 40.1 2.3 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CDJ41616.1 - 6.5e-09 35.3 0.1 1.3e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 CDJ41616.1 - 8.8e-07 29.0 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CDJ41616.1 - 0.036 13.5 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CDJ41616.1 - 0.073 12.5 0.0 0.5 9.8 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 21 DUF2933 PF11666.8 CDJ41616.1 - 0.26 11.3 1.6 0.71 10.0 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) PGM_PMM_III PF02880.16 CDJ41617.1 - 1e-25 90.2 0.0 2.1e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.16 CDJ41617.1 - 3e-10 39.9 0.0 5.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CDJ41617.1 - 4e-10 40.2 0.0 1e-09 38.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CDJ41617.1 - 0.0059 16.8 0.0 0.025 14.8 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Arf PF00025.21 CDJ41618.1 - 7.4e-76 253.5 0.0 8.6e-76 253.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDJ41618.1 - 2.4e-14 53.6 0.0 3.3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDJ41618.1 - 1.4e-13 50.7 0.0 1.7e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CDJ41618.1 - 2.4e-12 46.7 1.1 2.2e-08 33.7 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CDJ41618.1 - 3.9e-12 46.1 0.0 4.8e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CDJ41618.1 - 3.2e-09 36.5 0.0 3.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ41618.1 - 2.5e-05 24.3 0.0 4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CDJ41618.1 - 0.013 14.8 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase COX2 PF00116.20 CDJ41619.1 - 4.6e-43 145.9 0.0 6.2e-43 145.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain CS PF04969.16 CDJ41620.1 - 8.5e-06 26.7 0.0 0.00018 22.5 0.0 2.6 2 1 0 2 2 2 1 CS domain GYF_2 PF14237.6 CDJ41620.1 - 0.02 14.7 0.2 0.37 10.6 0.0 2.9 3 0 0 3 3 3 0 GYF domain 2 TatD_DNase PF01026.21 CDJ41620.1 - 0.024 14.0 0.2 5.5 6.3 0.0 2.5 2 0 0 2 2 2 0 TatD related DNase SR-25 PF10500.9 CDJ41620.1 - 0.038 13.6 29.1 0.053 13.1 7.1 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein CDC37_N PF03234.14 CDJ41620.1 - 0.069 14.1 0.6 0.069 14.1 0.6 3.8 4 1 0 4 4 4 0 Cdc37 N terminal kinase binding Ribosomal_L37 PF08561.10 CDJ41620.1 - 0.62 10.6 6.8 0.37 11.3 2.4 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 Ecl1 PF12855.7 CDJ41620.1 - 2.3 9.4 20.1 0.22 12.7 10.0 2.6 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins PIG-L PF02585.17 CDJ41621.1 - 3.6e-19 69.7 0.1 3.6e-18 66.5 0.0 2.4 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase Presenilin PF01080.17 CDJ41621.1 - 0.042 12.6 18.6 0.36 9.5 0.2 2.2 2 0 0 2 2 2 0 Presenilin DUF2052 PF09747.9 CDJ41621.1 - 0.061 13.5 15.9 1.6 8.8 9.5 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Zip PF02535.22 CDJ41621.1 - 0.062 12.5 4.8 0.071 12.3 0.1 2.4 2 1 0 2 2 2 0 ZIP Zinc transporter PIP5K PF01504.18 CDJ41621.1 - 0.074 12.3 5.4 0.27 10.4 2.7 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Afi1 PF07792.12 CDJ41621.1 - 0.079 13.4 10.3 1.8 9.1 6.6 2.6 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Connexin PF00029.19 CDJ41621.1 - 0.38 10.5 10.2 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Connexin SpoIIP PF07454.11 CDJ41621.1 - 0.88 9.0 13.7 1.3 8.4 7.5 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Med19 PF10278.9 CDJ41621.1 - 2.2 8.2 21.3 0.14 12.1 10.3 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 SID-1_RNA_chan PF13965.6 CDJ41621.1 - 2.4 6.5 3.8 7.1 4.9 2.0 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 CDJ41621.1 - 2.7 7.7 17.6 0.26 11.1 7.5 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ41621.1 - 3 6.8 12.5 1.8 7.5 7.2 2.2 2 0 0 2 2 2 0 Solute carrier family 12 Serinc PF03348.15 CDJ41621.1 - 3.4 6.5 6.2 10 4.9 3.0 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) EPL1 PF10513.9 CDJ41621.1 - 4.1 7.8 16.0 0.96 9.8 6.0 2.7 3 0 0 3 3 3 0 Enhancer of polycomb-like Tim54 PF11711.8 CDJ41621.1 - 4.6 5.9 14.2 2.3 6.9 6.6 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4746 PF15928.5 CDJ41621.1 - 5.2 6.4 16.9 2 7.7 9.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Plasmodium_Vir PF05795.11 CDJ41621.1 - 8.6 5.7 12.9 1.5 8.2 2.1 2.9 3 0 0 3 3 3 0 Plasmodium vivax Vir protein BCAS2 PF05700.11 CDJ41622.1 - 2.1e-43 148.4 7.0 3.1e-43 147.9 7.0 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Ribosomal_L16 PF00252.18 CDJ41623.1 - 2.3e-41 140.9 0.1 2.8e-41 140.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Peptidase_M20 PF01546.28 CDJ41625.1 - 5.4e-28 98.1 0.1 1.6e-27 96.5 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDJ41625.1 - 5.3e-11 42.4 0.1 2.2e-10 40.4 0.1 2.1 1 0 0 1 1 1 1 Peptidase dimerisation domain Pkinase PF00069.25 CDJ41626.1 - 1.9e-51 174.9 0.0 3.4e-51 174.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ41626.1 - 2.3e-21 76.3 0.0 4.6e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 CDJ41626.1 - 0.0008 19.6 2.0 0.0011 19.1 0.0 2.1 2 0 0 2 2 2 1 ABC1 family RIO1 PF01163.22 CDJ41626.1 - 0.0085 15.7 0.1 0.03 13.9 0.1 1.8 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CDJ41626.1 - 1.2 7.8 0.0 1.2 7.8 0.0 3.2 4 0 0 4 4 4 0 Fungal protein kinase CAF1C_H4-bd PF12265.8 CDJ41627.1 - 2.4e-15 56.5 0.0 6.7e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex KBP_C PF12309.8 CDJ41627.1 - 4.5e-10 39.6 26.0 4.5e-10 39.6 26.0 5.7 4 1 1 5 5 5 1 KIF-1 binding protein C terminal RskA PF10099.9 CDJ41627.1 - 6.5e-05 23.3 2.5 6.5e-05 23.3 2.5 11.7 4 2 5 10 10 10 2 Anti-sigma-K factor rskA SPX PF03105.19 CDJ41627.1 - 0.0025 17.8 5.3 0.0025 17.8 5.3 5.8 3 2 0 4 4 4 1 SPX domain TFIIA PF03153.13 CDJ41627.1 - 0.0039 17.3 11.6 0.0039 17.3 11.6 7.9 5 1 2 8 8 8 2 Transcription factor IIA, alpha/beta subunit Mito_carr PF00153.27 CDJ41628.1 - 2.7e-32 110.5 8.3 2.6e-18 65.7 0.0 4.0 4 0 0 4 4 4 3 Mitochondrial carrier protein RskA PF10099.9 CDJ41628.1 - 1.5 9.1 13.9 4.3 7.6 13.7 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ41629.1 - 0.003 17.6 29.0 0.0036 17.3 22.9 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 CDJ41629.1 - 0.35 10.2 26.3 0.68 9.3 26.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Neur_chan_memb PF02932.16 CDJ41629.1 - 0.95 9.5 10.2 0.93 9.5 8.9 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF111 PF01969.17 CDJ41629.1 - 1.8 7.6 7.0 2.7 7.0 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF111 Pex14_N PF04695.13 CDJ41629.1 - 3.3 8.3 19.0 5.8 7.6 14.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 CDJ41629.1 - 6.4 6.5 13.7 11 5.8 13.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PRP1_N PF06424.12 CDJ41629.1 - 6.5 7.2 11.5 14 6.0 11.5 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Exonuc_VII_L PF02601.15 CDJ41629.1 - 6.8 6.2 19.8 0.3 10.6 13.3 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Hydrolase_4 PF12146.8 CDJ41630.1 - 5.1e-20 71.8 0.3 1.7e-13 50.4 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ41630.1 - 1.6e-11 44.3 0.6 7e-08 32.4 0.1 2.8 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ41630.1 - 7.8e-10 39.7 0.3 1.4e-09 38.9 0.0 1.6 2 0 0 2 2 1 1 Alpha/beta hydrolase family DLH PF01738.18 CDJ41630.1 - 4.5e-08 32.9 0.0 2.9e-07 30.3 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 CDJ41630.1 - 5.1e-07 29.8 0.0 0.02 14.8 0.0 2.4 1 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 CDJ41630.1 - 1.1e-06 28.3 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CDJ41630.1 - 4.8e-05 23.1 4.5 0.0071 16.0 0.0 3.1 2 2 0 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 CDJ41630.1 - 5.4e-05 23.0 0.0 0.00043 20.0 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CDJ41630.1 - 6.4e-05 22.9 0.0 0.028 14.2 0.0 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 CDJ41630.1 - 0.00012 22.3 0.1 0.00037 20.7 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain AXE1 PF05448.12 CDJ41630.1 - 0.00045 19.0 0.0 0.0014 17.3 0.1 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF1057 PF06342.12 CDJ41630.1 - 0.00056 19.0 0.0 0.018 14.1 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) DUF818 PF05677.12 CDJ41630.1 - 0.00071 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Esterase PF00756.20 CDJ41630.1 - 0.00081 19.1 0.0 0.0021 17.7 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 CDJ41630.1 - 0.0013 18.5 0.0 0.041 13.7 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CDJ41630.1 - 0.002 18.1 0.0 0.0054 16.6 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 CDJ41630.1 - 0.0087 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein LIP PF03583.14 CDJ41630.1 - 0.012 15.0 5.9 1.1 8.6 0.0 3.2 3 1 0 3 3 3 0 Secretory lipase DUF2974 PF11187.8 CDJ41630.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 CDJ41630.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 CDJ41630.1 - 0.028 14.0 0.0 1.1 8.8 0.0 2.2 1 1 0 2 2 2 0 Lipid-droplet associated hydrolase UPF0227 PF05728.12 CDJ41630.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PIRT PF15099.6 CDJ41630.1 - 0.066 12.8 0.7 6.2 6.4 0.0 3.0 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family LCAT PF02450.15 CDJ41630.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF4589 PF15252.6 CDJ41631.1 - 1.2 9.1 14.3 2 8.4 14.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) TFIIA PF03153.13 CDJ41631.1 - 1.4 8.9 17.6 2.2 8.2 17.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 CDJ41631.1 - 2 7.0 9.4 2.4 6.7 9.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 CDJ41631.1 - 3.3 6.5 7.9 4.3 6.1 7.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ41631.1 - 9.8 4.8 7.5 11 4.6 7.5 1.1 1 0 0 1 1 1 0 Presenilin TAFII55_N PF04658.13 CDJ41632.1 - 1.1e-17 64.2 0.0 1.1e-17 64.2 0.0 3.7 3 1 0 3 3 3 1 TAFII55 protein conserved region SUIM_assoc PF16619.5 CDJ41632.1 - 0.01 15.9 8.5 0.01 15.9 8.5 5.4 4 1 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ41632.1 - 0.24 11.3 49.5 0.51 10.3 11.4 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ41632.1 - 6.9 6.7 16.6 5.8 6.9 0.3 3.1 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region NepR PF18557.1 CDJ41634.1 - 0.14 11.8 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Anti-sigma factor NepR Hydrolase_4 PF12146.8 CDJ41635.1 - 9.3e-14 51.3 0.0 1.7e-08 34.1 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ41635.1 - 4.7e-11 42.8 0.0 7.6e-06 25.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 CDJ41635.1 - 1.8e-07 30.2 0.0 0.0045 15.7 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 CDJ41635.1 - 7.2e-06 25.6 0.0 1.5e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CDJ41635.1 - 1.6e-05 25.6 0.0 4.5e-05 24.1 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 CDJ41635.1 - 0.00018 21.2 0.0 0.001 18.7 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 CDJ41635.1 - 0.00041 20.0 0.0 0.0026 17.4 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 CDJ41635.1 - 0.0009 19.2 0.0 0.0018 18.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 CDJ41635.1 - 0.002 17.9 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.12 CDJ41635.1 - 0.0045 16.0 0.0 0.0061 15.6 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.11 CDJ41635.1 - 0.005 16.8 0.0 0.057 13.3 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 CDJ41635.1 - 0.0077 16.1 0.0 0.049 13.4 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 CDJ41635.1 - 0.0093 15.5 0.0 0.19 11.3 0.0 2.3 1 1 1 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 CDJ41635.1 - 0.18 11.5 0.0 1.5 8.6 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family LRR_8 PF13855.6 CDJ41636.1 - 0.55 10.0 2.1 7.2 6.4 0.1 3.4 3 0 0 3 3 3 0 Leucine rich repeat DUF1852 PF08908.11 CDJ41639.1 - 0.054 12.5 0.3 0.37 9.7 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1852) TMEM192 PF14802.6 CDJ41639.1 - 0.074 12.1 0.8 0.097 11.8 0.8 1.3 1 0 0 1 1 1 0 TMEM192 family Spc7 PF08317.11 CDJ41640.1 - 0.0031 16.4 18.2 0.0037 16.2 18.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein TMCO5 PF14992.6 CDJ41640.1 - 0.0042 16.7 14.6 0.0052 16.4 14.6 1.1 1 0 0 1 1 1 1 TMCO5 family SlyX PF04102.12 CDJ41640.1 - 0.0043 17.6 9.6 0.0043 17.6 9.6 2.9 1 1 1 2 2 2 1 SlyX TPR_MLP1_2 PF07926.12 CDJ41640.1 - 0.019 15.0 24.8 0.024 14.7 24.8 1.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein BRE1 PF08647.11 CDJ41640.1 - 0.021 14.9 16.7 0.027 14.5 16.7 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Exonuc_VII_L PF02601.15 CDJ41640.1 - 0.058 12.9 13.6 0.067 12.8 13.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.8 CDJ41640.1 - 0.08 10.4 17.3 0.095 10.2 17.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SnoaL_2 PF12680.7 CDJ41640.1 - 0.097 13.3 0.3 0.16 12.6 0.3 1.5 1 1 0 1 1 1 0 SnoaL-like domain APG17 PF04108.12 CDJ41640.1 - 0.11 11.5 13.9 0.13 11.4 13.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 YhfZ_C PF14503.6 CDJ41640.1 - 0.2 11.2 7.0 0.23 11.0 7.0 1.1 1 0 0 1 1 1 0 YhfZ C-terminal domain HMMR_N PF15905.5 CDJ41640.1 - 0.24 10.8 21.4 0.065 12.7 12.2 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal OmpH PF03938.14 CDJ41640.1 - 0.3 11.4 23.4 0.44 10.9 23.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc29 PF17082.5 CDJ41640.1 - 0.35 10.7 7.9 0.49 10.2 7.6 1.3 1 1 0 1 1 1 0 Spindle Pole Component 29 DUF16 PF01519.16 CDJ41640.1 - 0.54 10.8 19.1 0.12 12.9 4.0 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 HrpB7 PF09486.10 CDJ41640.1 - 0.58 10.5 25.3 8.9 6.7 25.5 2.0 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) IFT20 PF14931.6 CDJ41640.1 - 0.59 10.3 20.7 0.1 12.8 9.8 2.4 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF3138 PF11336.8 CDJ41640.1 - 0.8 8.3 9.6 0.92 8.0 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RRP36 PF06102.12 CDJ41640.1 - 0.83 9.6 13.8 1.1 9.2 13.8 1.1 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF4407 PF14362.6 CDJ41640.1 - 0.84 8.9 19.3 1 8.7 19.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 CDJ41640.1 - 0.92 8.5 17.4 2.1 7.3 17.4 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM117 PF15388.6 CDJ41640.1 - 1.3 8.4 10.2 1.5 8.2 10.2 1.0 1 0 0 1 1 1 0 Protein Family FAM117 ADIP PF11559.8 CDJ41640.1 - 1.4 9.0 23.9 0.48 10.5 7.3 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ExsD PF16806.5 CDJ41640.1 - 1.4 8.8 16.6 2.8 7.8 16.5 1.5 1 1 0 1 1 1 0 Antiactivator protein ExsD V_ATPase_I PF01496.19 CDJ41640.1 - 1.4 6.7 11.2 1.4 6.7 11.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bud13 PF09736.9 CDJ41640.1 - 1.7 9.0 12.9 2.2 8.6 12.9 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DOR PF14839.6 CDJ41640.1 - 1.9 8.4 13.8 2.4 8.1 13.8 1.2 1 0 0 1 1 1 0 DOR family UPF0242 PF06785.11 CDJ41640.1 - 1.9 8.6 17.5 2.7 8.1 17.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 CDJ41640.1 - 2.5 7.3 25.7 19 4.4 25.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) HDAC4_Gln PF12203.8 CDJ41640.1 - 2.6 8.3 29.5 1.5 9.1 17.1 2.1 1 1 1 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 Cob_adeno_trans PF01923.18 CDJ41640.1 - 3 8.0 10.2 6.5 6.9 10.2 1.5 1 1 0 1 1 1 0 Cobalamin adenosyltransferase DUF4200 PF13863.6 CDJ41640.1 - 3.7 8.0 25.7 13 6.2 25.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) USP8_interact PF08941.10 CDJ41640.1 - 3.9 7.2 16.3 87 2.9 16.3 2.1 1 1 0 1 1 1 0 USP8 interacting HAUS6_N PF14661.6 CDJ41640.1 - 4.1 6.9 14.5 5.2 6.6 14.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Phage_GPO PF05929.11 CDJ41640.1 - 4.6 6.8 17.6 7.5 6.1 17.6 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase PV-1 PF06637.11 CDJ41640.1 - 8 5.2 20.8 14 4.4 20.8 1.4 1 1 0 1 1 1 0 PV-1 protein (PLVAP) XRN_M PF17846.1 CDJ41640.1 - 9.3 5.1 9.4 10 4.9 9.4 1.0 1 0 0 1 1 1 0 Xrn1 helical domain CENP-Q PF13094.6 CDJ41640.1 - 9.9 6.3 21.4 33 4.6 21.4 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Pkinase PF00069.25 CDJ41641.1 - 1.2e-44 152.7 0.0 2.4e-44 151.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ41641.1 - 3.8e-21 75.6 0.0 6.6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase GLTT PF01744.20 CDJ41641.1 - 0.36 10.7 2.2 0.72 9.7 2.2 1.5 1 0 0 1 1 1 0 GLTT repeat (6 copies) Peptidase_C48 PF02902.19 CDJ41642.1 - 3.1e-17 63.1 0.8 1.6e-12 47.8 0.0 2.3 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain SPX PF03105.19 CDJ41643.1 - 0.15 12.0 15.5 0.72 9.7 15.5 2.0 1 1 0 1 1 1 0 SPX domain Glt_symporter PF03616.14 CDJ41643.1 - 0.3 9.7 5.2 0.045 12.4 0.7 1.8 2 0 0 2 2 2 0 Sodium/glutamate symporter EPL1 PF10513.9 CDJ41643.1 - 1.3 9.4 16.3 3.6 8.0 2.3 3.2 3 0 0 3 3 3 0 Enhancer of polycomb-like Connexin PF00029.19 CDJ41643.1 - 4.2 7.1 5.6 36 4.0 0.3 2.8 3 0 0 3 3 3 0 Connexin TFIIA PF03153.13 CDJ41643.1 - 7.7 6.4 53.9 0.11 12.4 19.7 2.3 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GCS PF03074.16 CDJ41646.1 - 3e-101 339.4 5.0 2.5e-54 185.1 0.0 3.5 4 0 0 4 4 4 3 Glutamate-cysteine ligase SUIM_assoc PF16619.5 CDJ41646.1 - 0.023 14.8 0.1 0.023 14.8 0.1 4.6 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ41647.1 - 0.015 15.0 20.1 0.016 14.8 20.1 1.1 1 0 0 1 1 1 0 Spt20 family PsbQ PF05757.11 CDJ41647.1 - 0.025 14.3 9.2 0.03 14.1 9.2 1.1 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Med15 PF09606.10 CDJ41647.1 - 0.057 12.1 13.8 0.06 12.0 13.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pep1_7 PF17232.2 CDJ41647.1 - 0.13 12.7 2.9 2.4 8.7 0.3 2.1 2 0 0 2 2 2 0 Elicitor peptide 1-7 TFIIA PF03153.13 CDJ41647.1 - 0.14 12.1 20.1 0.16 12.0 20.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FTZ PF03867.14 CDJ41647.1 - 0.16 11.4 12.0 0.19 11.2 12.0 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region BNR_3 PF13859.6 CDJ41647.1 - 0.2 10.9 3.6 0.23 10.7 3.6 1.0 1 0 0 1 1 1 0 BNR repeat-like domain Arb1 PF09692.10 CDJ41647.1 - 0.39 9.8 8.2 0.45 9.6 8.2 1.0 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 MPM1 PF17234.2 CDJ41647.1 - 1.1 9.5 9.9 1.4 9.2 9.9 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Otopetrin PF03189.13 CDJ41647.1 - 1.2 7.9 5.1 1.3 7.7 5.1 1.0 1 0 0 1 1 1 0 Otopetrin Spore_III_AF PF09581.10 CDJ41647.1 - 1.2 9.1 10.6 1.5 8.8 10.6 1.0 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) SPICE PF15678.5 CDJ41647.1 - 1.3 8.3 16.8 1.5 8.1 16.8 1.0 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression BORG_CEP PF14957.6 CDJ41647.1 - 1.3 10.2 5.4 1.9 9.7 5.4 1.2 1 0 0 1 1 1 0 Cdc42 effector DUF4769 PF15992.5 CDJ41647.1 - 1.3 8.7 8.1 1.6 8.4 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) Adeno_PV PF03910.13 CDJ41647.1 - 1.4 7.6 8.2 1.5 7.4 8.2 1.0 1 0 0 1 1 1 0 Adenovirus minor core protein PV Mitofilin PF09731.9 CDJ41647.1 - 1.5 7.6 20.8 1.6 7.5 20.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MMR1 PF08505.10 CDJ41647.1 - 2.3 8.5 10.4 2.7 8.2 10.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein BAT2_N PF07001.11 CDJ41647.1 - 2.3 8.6 16.9 2.7 8.4 16.9 1.1 1 0 0 1 1 1 0 BAT2 N-terminus BAF1_ABF1 PF04684.13 CDJ41647.1 - 2.3 7.2 13.8 2.5 7.0 13.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3381 PF11861.8 CDJ41647.1 - 2.4 7.9 11.9 3 7.6 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Sin_N PF04801.13 CDJ41647.1 - 2.9 7.0 18.4 3.5 6.7 18.4 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region EBP50_C PF09007.11 CDJ41647.1 - 3.3 8.7 13.1 4.4 8.3 13.1 1.1 1 0 0 1 1 1 0 EBP50, C-terminal XRN_M PF17846.1 CDJ41647.1 - 3.9 6.3 10.3 4.3 6.2 10.3 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Ureide_permease PF07168.11 CDJ41647.1 - 3.9 6.1 6.8 4.6 5.9 6.8 1.0 1 0 0 1 1 1 0 Ureide permease Neur_chan_memb PF02932.16 CDJ41647.1 - 6.6 6.7 9.6 7.3 6.6 9.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RIFIN PF02009.16 CDJ41647.1 - 7.8 6.3 14.2 9.3 6.0 14.2 1.1 1 0 0 1 1 1 0 Rifin Roughex PF06020.11 CDJ41647.1 - 8.1 5.4 13.2 9.3 5.2 13.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 CDJ41647.1 - 8.7 5.0 13.6 9.5 4.9 13.6 1.0 1 0 0 1 1 1 0 Presenilin NuA4 PF09340.10 CDJ41648.1 - 2e-17 62.8 0.4 4.8e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Herpes_US12 PF05363.12 CDJ41648.1 - 0.0034 18.1 0.3 0.0034 18.1 0.3 2.1 2 1 0 2 2 2 1 Herpesvirus US12 family TFIIA PF03153.13 CDJ41648.1 - 2.2 8.2 24.8 2.6 7.9 24.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ41648.1 - 4.8 5.3 16.7 5.2 5.2 16.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-CDGSH PF09360.10 CDJ41649.1 - 0.00022 21.3 2.9 0.00022 21.3 2.9 1.9 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type tRNA_bind PF01588.20 CDJ41651.1 - 1.1e-23 83.1 0.0 2e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 CDJ41651.1 - 1e-06 28.8 0.0 1e-06 28.8 0.0 2.2 2 0 0 2 2 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ41651.1 - 3.8e-05 23.8 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ41651.1 - 0.011 15.8 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PBP_sp32 PF07222.12 CDJ41651.1 - 0.034 13.6 5.5 0.068 12.6 5.5 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Mss4 PF04421.13 CDJ41651.1 - 0.076 13.2 0.6 0.96 9.6 0.0 2.4 2 0 0 2 2 2 0 Mss4 protein FAM176 PF14851.6 CDJ41651.1 - 0.18 11.5 3.9 0.36 10.5 3.9 1.4 1 0 0 1 1 1 0 FAM176 family Macoilin PF09726.9 CDJ41651.1 - 0.19 10.2 10.6 0.29 9.7 10.6 1.2 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 CDJ41651.1 - 0.35 9.5 5.0 0.47 9.1 5.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 CDJ41651.1 - 1 9.3 7.3 2 8.3 7.3 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NOZZLE PF08744.10 CDJ41651.1 - 1.1 8.7 4.1 1.7 8.1 4.1 1.2 1 0 0 1 1 1 0 Plant transcription factor NOZZLE Presenilin PF01080.17 CDJ41651.1 - 1.6 7.4 7.3 2.2 7.0 7.3 1.2 1 0 0 1 1 1 0 Presenilin TraV PF09676.10 CDJ41651.1 - 1.9 9.5 9.9 4.8 8.2 9.9 1.7 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Neur_chan_memb PF02932.16 CDJ41651.1 - 3.5 7.6 6.0 5.8 6.9 6.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2477 PF10631.9 CDJ41651.1 - 9.6 6.9 10.8 8.7 7.0 8.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2477) Hydrolase_4 PF12146.8 CDJ41653.1 - 3.8e-13 49.3 0.3 1.8e-12 47.0 0.3 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 CDJ41653.1 - 9.7e-07 27.8 0.0 0.0048 15.6 0.0 3.1 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 CDJ41653.1 - 3.4e-06 26.9 0.0 7.9e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 CDJ41653.1 - 6.6e-06 25.9 0.0 0.00012 21.8 0.0 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 CDJ41653.1 - 9.2e-06 25.7 0.3 2.7e-05 24.1 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ41653.1 - 2.4e-05 25.0 1.2 2.4e-05 25.0 1.2 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CDJ41653.1 - 0.00044 19.8 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Lipase_3 PF01764.25 CDJ41653.1 - 0.029 14.2 0.1 0.029 14.2 0.1 1.7 2 0 0 2 2 2 0 Lipase (class 3) HOOK PF05622.12 CDJ41654.1 - 0.00084 17.6 27.0 0.00096 17.4 27.0 1.1 1 0 0 1 1 1 1 HOOK protein Filament PF00038.21 CDJ41654.1 - 0.0096 15.5 23.7 0.014 15.0 23.7 1.3 1 0 0 1 1 1 1 Intermediate filament protein Cep57_CLD_2 PF14197.6 CDJ41654.1 - 0.018 15.1 29.3 0.048 13.7 5.0 3.4 2 2 0 2 2 2 0 Centrosome localisation domain of PPC89 Shugoshin_N PF07558.11 CDJ41654.1 - 0.019 14.8 0.8 0.019 14.8 0.8 2.6 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region HIP1_clath_bdg PF16515.5 CDJ41654.1 - 0.025 15.2 4.8 0.025 15.2 4.8 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 VPS11_C PF12451.8 CDJ41654.1 - 0.032 14.5 0.5 0.032 14.5 0.5 3.5 3 1 1 4 4 4 0 Vacuolar protein sorting protein 11 C terminal TSC22 PF01166.18 CDJ41654.1 - 0.045 14.1 10.5 0.21 11.9 2.1 3.6 2 1 1 3 3 3 0 TSC-22/dip/bun family DUF720 PF05302.11 CDJ41654.1 - 0.082 12.8 2.8 0.31 10.9 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF720) HALZ PF02183.18 CDJ41654.1 - 0.096 12.9 9.0 4.1 7.7 0.0 4.0 4 0 0 4 4 3 0 Homeobox associated leucine zipper Amino_oxidase PF01593.24 CDJ41654.1 - 0.098 11.9 2.3 0.11 11.8 1.7 1.3 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase Syntaxin PF00804.25 CDJ41654.1 - 0.12 12.1 19.5 0.064 12.9 7.3 2.2 1 1 1 2 2 2 0 Syntaxin KASH_CCD PF14662.6 CDJ41654.1 - 0.17 11.7 25.6 0.28 11.0 21.4 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH TolA_bind_tri PF16331.5 CDJ41654.1 - 0.18 11.9 20.8 1.5 9.0 2.8 3.3 1 1 2 3 3 3 0 TolA binding protein trimerisation FlaC_arch PF05377.11 CDJ41654.1 - 0.18 12.2 6.5 13 6.3 0.2 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 CDJ41654.1 - 0.5 10.1 8.1 1.9 8.2 6.2 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DASH_Dam1 PF08653.10 CDJ41654.1 - 0.51 10.2 5.3 1.2 9.0 0.3 3.0 3 1 0 3 3 3 0 DASH complex subunit Dam1 KxDL PF10241.9 CDJ41654.1 - 1.3 9.3 19.0 0.1 12.9 1.9 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein ZapB PF06005.12 CDJ41654.1 - 1.7 9.2 33.5 4.4 7.8 14.0 3.4 2 1 1 3 3 3 0 Cell division protein ZapB Cnn_1N PF07989.11 CDJ41654.1 - 1.9 8.7 21.9 2.5 8.3 3.5 2.9 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 YabA PF06156.13 CDJ41654.1 - 2.3 8.9 20.8 2.1 9.0 2.9 3.0 1 1 2 3 3 3 0 Initiation control protein YabA PRKG1_interact PF15898.5 CDJ41654.1 - 3.3 8.7 27.5 0.2 12.5 12.9 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Baculo_F PF12259.8 CDJ41654.1 - 5.5 5.4 9.1 1.1 7.7 4.2 1.8 1 1 1 2 2 2 0 Baculovirus F protein Fez1 PF06818.15 CDJ41654.1 - 6.6 7.1 28.4 1.2 9.5 16.7 2.0 1 1 1 2 2 2 0 Fez1 FtsX_ECD PF18075.1 CDJ41654.1 - 6.6 7.4 8.2 1 10.0 0.3 2.9 1 1 2 3 3 3 0 FtsX extracellular domain Spc24 PF08286.11 CDJ41654.1 - 6.9 7.0 22.7 2.3 8.5 2.8 3.1 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 NRBF2 PF08961.10 CDJ41654.1 - 7.1 6.2 21.5 1.3 8.5 4.3 2.8 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator Spc7 PF08317.11 CDJ41654.1 - 8.6 5.1 27.2 30 3.3 26.4 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 CDJ41654.1 - 9.3 6.9 14.8 22 5.7 10.6 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Prominin PF05478.11 CDJ41654.1 - 9.5 4.0 10.5 14 3.4 10.4 1.3 1 1 0 1 1 1 0 Prominin DEAD PF00270.29 CDJ41655.1 - 4.4e-05 23.3 0.0 0.00019 21.3 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ41655.1 - 0.00011 22.3 0.0 0.0019 18.2 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SUIM_assoc PF16619.5 CDJ41655.1 - 4.7 7.4 86.5 0.15 12.2 2.6 8.2 7 0 0 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 Helicase_C PF00271.31 CDJ41656.1 - 5e-05 23.6 0.0 0.00087 19.6 0.0 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ41656.1 - 0.0001 22.1 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Glyoxalase_5 PF14696.6 CDJ41657.1 - 0.05 13.8 0.3 0.071 13.3 0.3 1.2 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal SR-25 PF10500.9 CDJ41658.1 - 0.00015 21.4 21.0 0.00023 20.9 21.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SOBP PF15279.6 CDJ41658.1 - 0.024 15.2 5.2 0.027 15.1 5.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4603 PF15376.6 CDJ41658.1 - 0.33 8.3 12.7 0.39 8.0 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Spem1 PF15670.5 CDJ41658.1 - 2.3 7.7 10.1 3.2 7.3 10.1 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Arf PF00025.21 CDJ41661.1 - 1.4e-68 229.8 0.0 1.7e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDJ41661.1 - 1.2e-12 48.1 0.0 2.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDJ41661.1 - 4.5e-11 42.5 0.0 5.9e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CDJ41661.1 - 2.6e-10 40.0 0.1 1e-07 31.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CDJ41661.1 - 6.3e-09 35.6 0.0 8e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CDJ41661.1 - 2.2e-08 33.7 0.0 2.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ41661.1 - 4.1e-05 23.6 0.0 7.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ41661.1 - 0.033 13.7 0.6 0.18 11.3 0.6 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDJ41662.1 - 2.2e-39 135.0 0.2 2.5e-39 134.8 0.2 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ41662.1 - 1.1e-06 28.7 0.1 7.1e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDJ41662.1 - 0.0032 16.9 0.1 0.012 15.0 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 CDJ41662.1 - 0.15 12.1 0.0 9.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.27 CDJ41663.1 - 5.5e-51 172.9 0.0 9.1e-51 172.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDJ41663.1 - 8.6e-41 138.8 0.1 2.7e-40 137.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDJ41663.1 - 2.2e-15 56.8 1.0 4.6e-15 55.8 0.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ41663.1 - 1.2e-05 25.4 0.0 0.00052 20.1 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDJ41663.1 - 0.0038 16.7 0.1 0.019 14.4 0.1 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 CDJ41663.1 - 0.0051 16.7 1.0 0.011 15.6 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 FlpD PF02662.16 CDJ41663.1 - 0.0061 16.5 0.1 0.016 15.2 0.0 1.7 2 0 0 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit Semialdhyde_dhC PF02774.18 CDJ41663.1 - 0.022 14.8 0.1 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain gpW PF02831.15 CDJ41663.1 - 0.15 12.0 0.0 16 5.5 0.0 2.5 2 0 0 2 2 2 0 gpW MOLO1 PF17175.4 CDJ41664.1 - 3e-14 53.1 0.1 7.7e-11 42.2 0.0 2.1 1 1 1 2 2 2 2 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 CDJ41664.1 - 0.23 11.7 0.0 1.3 9.2 0.0 2.0 1 1 0 1 1 1 0 TPM domain Fer2 PF00111.27 CDJ41665.1 - 2.5e-05 24.1 4.3 2.5e-05 24.1 4.3 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Peptidase_S15 PF02129.18 CDJ41665.1 - 2.7 7.5 10.4 0.34 10.4 6.4 1.5 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2722 PF10846.8 CDJ41666.1 - 0.00096 18.2 6.3 0.00096 18.2 6.3 3.8 3 1 0 3 3 3 1 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ41666.1 - 0.6 8.7 85.9 0.77 8.4 85.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MRP-S31 PF15433.6 CDJ41666.1 - 6.1 6.4 37.9 9.2 5.8 37.9 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Caldesmon PF02029.15 CDJ41666.1 - 7 5.3 45.6 11 4.6 45.6 1.2 1 0 0 1 1 1 0 Caldesmon Hamartin PF04388.12 CDJ41666.1 - 8.1 5.0 41.3 11 4.5 41.3 1.1 1 0 0 1 1 1 0 Hamartin protein Tic110 PF16940.5 CDJ41667.1 - 6.4 5.1 9.6 6.8 5.0 9.6 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter DUF572 PF04502.13 CDJ41669.1 - 0.058 13.0 21.9 0.084 12.5 21.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GREB1 PF15782.5 CDJ41669.1 - 3.6 4.6 17.9 4.2 4.4 17.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Rtf2 PF04641.12 CDJ41669.1 - 9.8 5.5 21.6 2.5 7.4 15.1 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger CSG2 PF16965.5 CDJ41669.1 - 9.9 5.0 6.1 18 4.2 6.1 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator IER PF05760.12 CDJ41670.1 - 1.7 8.9 3.9 3.1 8.0 3.9 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) YppF PF14178.6 CDJ41674.1 - 0.099 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 YppF-like protein HECT PF00632.25 CDJ41675.1 - 9.7e-52 176.3 0.0 1.9e-51 175.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) GILT PF03227.16 CDJ41676.1 - 4.2e-23 81.6 0.3 1.2e-22 80.2 0.3 1.7 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Choline_transpo PF04515.12 CDJ41678.1 - 9.6e-19 67.7 4.2 1.5e-18 67.1 1.3 2.5 2 1 1 3 3 3 1 Plasma-membrane choline transporter Megourin PF17560.2 CDJ41679.1 - 0.042 14.1 0.1 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 Aphid Megourins Asp_protease_2 PF13650.6 CDJ41680.1 - 2.3e-07 31.3 0.0 5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ41680.1 - 3.1e-06 27.6 0.0 6.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ41680.1 - 1.2e-05 25.1 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 CDJ41680.1 - 0.15 11.8 0.0 0.37 10.5 0.1 1.6 1 1 1 2 2 2 0 Putative peptidase (DUF1758) Retrotrans_gag PF03732.17 CDJ41681.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.6 2 0 0 2 2 2 0 Retrotransposon gag protein NYD-SP28_assoc PF14775.6 CDJ41682.1 - 0.24 11.5 0.5 0.93 9.6 0.1 2.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain COPI_assoc PF08507.10 CDJ41685.1 - 5.7e-07 29.6 3.7 7.3e-07 29.3 3.7 1.1 1 0 0 1 1 1 1 COPI associated protein G-patch PF01585.23 CDJ41686.1 - 1.3e-14 53.8 1.1 2.1e-14 53.1 1.1 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDJ41686.1 - 0.00045 20.3 0.6 0.0013 18.8 0.6 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 CDJ41686.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBP4 PF07960.11 CDJ41686.1 - 0.032 14.1 0.3 0.067 13.0 0.3 1.5 1 0 0 1 1 1 0 CBP4 ALS2CR11 PF15729.5 CDJ41686.1 - 0.22 10.7 0.3 0.31 10.1 0.3 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 AAA_12 PF13087.6 CDJ41687.1 - 1.2e-51 175.2 0.0 2.2e-51 174.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ41687.1 - 1.1e-43 149.9 3.9 1.6e-26 93.6 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 CDJ41687.1 - 2.8e-11 43.5 0.0 1.2e-10 41.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ41687.1 - 1.4e-09 38.4 0.0 5.4e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 CDJ41687.1 - 6.8e-05 22.2 0.0 0.0064 15.7 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.9 CDJ41687.1 - 0.00038 19.8 0.2 0.062 12.5 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CDJ41687.1 - 0.0011 18.9 0.0 0.0031 17.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.16 CDJ41687.1 - 0.002 17.6 0.0 0.014 14.8 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 CDJ41687.1 - 0.0026 17.8 0.0 0.0059 16.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 CDJ41687.1 - 0.0032 18.1 0.1 1.1 10.1 0.0 3.1 3 0 0 3 3 2 1 Double-stranded RNA binding motif IstB_IS21 PF01695.17 CDJ41687.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 CDJ41687.1 - 0.014 15.1 0.0 1.7 8.4 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 CDJ41687.1 - 0.018 15.5 0.0 0.086 13.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ41687.1 - 0.021 14.5 0.1 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain UvrD-helicase PF00580.21 CDJ41687.1 - 0.032 13.8 0.3 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DEAD PF00270.29 CDJ41687.1 - 0.077 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 CDJ41687.1 - 0.095 12.1 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CDJ41687.1 - 0.1 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DSPc PF00782.20 CDJ41688.1 - 1.2e-19 70.5 0.0 2.6e-17 62.9 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 CDJ41688.1 - 0.032 14.1 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 Gelsolin repeat Y_phosphatase PF00102.27 CDJ41688.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CLU PF13236.6 CDJ41689.1 - 0.0098 15.7 0.0 0.026 14.3 0.0 1.6 2 0 0 2 2 2 1 Clustered mitochondria TPR_12 PF13424.6 CDJ41690.1 - 0.024 14.9 0.5 0.075 13.3 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat MORN PF02493.20 CDJ41691.1 - 1.5e-21 74.9 35.6 0.00093 19.0 0.0 9.2 10 0 0 10 10 10 6 MORN repeat Avl9 PF09794.9 CDJ41691.1 - 2.3e-11 43.0 0.1 1.1e-10 40.8 0.0 1.7 1 1 1 2 2 2 1 Transport protein Avl9 DENN PF02141.21 CDJ41691.1 - 0.0022 18.0 1.1 0.0048 16.9 0.5 1.8 2 0 0 2 2 2 1 DENN (AEX-3) domain PDZ PF00595.24 CDJ41693.1 - 4e-05 23.9 0.0 8.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ41693.1 - 4.2e-05 23.3 0.0 0.00015 21.6 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ41693.1 - 0.071 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PAP2 PF01569.21 CDJ41695.1 - 5.1e-22 78.1 1.0 5.1e-22 78.1 1.0 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CDJ41695.1 - 0.17 12.5 0.3 0.17 12.5 0.3 3.5 4 0 0 4 4 4 0 PAP2 superfamily C-terminal ADK PF00406.22 CDJ41696.1 - 7.4e-56 188.4 0.0 1.1e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDJ41696.1 - 9e-29 100.6 0.1 4.7e-28 98.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CDJ41696.1 - 4.6e-17 61.7 1.5 6.6e-17 61.2 0.1 2.1 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 CDJ41696.1 - 1.7e-09 38.0 0.0 7.7e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 CDJ41696.1 - 7.2e-08 32.9 1.6 3.7e-05 24.1 0.2 2.5 2 1 1 3 3 3 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 CDJ41696.1 - 3.5e-05 24.3 0.0 0.00011 22.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CDJ41696.1 - 0.0068 16.7 0.1 0.034 14.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain DAP3 PF10236.9 CDJ41696.1 - 0.073 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 CAML PF14963.6 CDJ41697.1 - 0.057 13.5 0.7 0.086 12.9 0.7 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Hydrolase_4 PF12146.8 CDJ41698.1 - 6.2e-05 22.4 3.6 0.15 11.3 0.0 3.1 3 1 1 4 4 4 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CDJ41698.1 - 0.059 13.2 0.3 0.36 10.6 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 CDJ41698.1 - 0.075 12.7 0.5 0.63 9.6 0.0 2.5 2 1 0 3 3 3 0 alpha/beta hydrolase fold Na_Ca_ex PF01699.24 CDJ41700.1 - 2.8e-35 121.5 40.9 1.3e-20 73.9 18.9 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Ribosomal_L37ae PF01780.19 CDJ41701.1 - 6.3e-41 138.4 8.4 7.2e-41 138.2 8.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 CDJ41701.1 - 0.0016 18.4 1.9 0.0023 17.8 1.9 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Zn_ribbon_SprT PF17283.2 CDJ41701.1 - 0.012 15.5 1.7 0.022 14.7 1.7 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Elf1 PF05129.13 CDJ41701.1 - 0.022 14.8 1.2 0.04 14.0 1.2 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.6 CDJ41701.1 - 0.026 14.0 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CDJ41701.1 - 0.056 13.6 0.2 0.33 11.1 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 CDJ41701.1 - 0.082 12.7 2.1 2.3 8.0 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Di19 PF05605.12 CDJ41701.1 - 0.22 11.9 0.8 0.22 11.9 0.8 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 CDJ41701.1 - 1.5 9.3 5.8 0.88 10.1 1.7 2.3 1 1 1 2 2 2 0 Zinc-finger double domain HSP70 PF00012.20 CDJ41702.1 - 4.4e-99 332.3 1.8 5.1e-93 312.3 0.0 2.5 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 CDJ41702.1 - 1.3e-05 24.2 0.0 0.00013 20.9 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CDJ41702.1 - 0.0048 16.6 1.0 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FBPase_2 PF06874.11 CDJ41702.1 - 0.12 10.7 0.9 0.17 10.1 0.9 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase Hydrolase_4 PF12146.8 CDJ41703.1 - 8.5e-12 44.9 10.1 0.00046 19.5 0.0 4.4 3 1 0 4 4 4 3 Serine aminopeptidase, S33 SpoIIP PF07454.11 CDJ41703.1 - 0.0019 17.7 10.3 0.0027 17.2 6.3 2.2 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) SAPS PF04499.15 CDJ41703.1 - 0.0051 15.7 5.4 0.036 12.9 2.5 2.1 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein UPF0227 PF05728.12 CDJ41703.1 - 0.036 14.0 0.0 0.036 14.0 0.0 2.5 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0227) DUF2227 PF09988.9 CDJ41703.1 - 0.17 11.7 0.1 0.17 11.7 0.1 1.9 2 1 0 2 2 1 0 Uncharacterized metal-binding protein (DUF2227) Apt1 PF10351.9 CDJ41703.1 - 0.54 9.1 6.9 7.4 5.3 6.8 2.4 2 1 1 3 3 3 0 Golgi-body localisation protein domain Zip PF02535.22 CDJ41703.1 - 0.66 9.1 6.2 0.86 8.7 4.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2370 PF10176.9 CDJ41703.1 - 2.4 7.8 8.3 1.4 8.5 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF2052 PF09747.9 CDJ41703.1 - 4 7.5 25.6 4.9 7.2 16.7 2.6 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) DUF913 PF06025.12 CDJ41703.1 - 4.6 6.1 14.7 1 8.2 5.8 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) EPL1 PF10513.9 CDJ41703.1 - 6.2 7.2 17.5 23 5.3 13.2 3.0 3 0 0 3 3 3 0 Enhancer of polycomb-like Hydrolase_4 PF12146.8 CDJ41704.1 - 5.8e-05 22.5 0.4 9.8e-05 21.7 0.4 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ41704.1 - 0.00011 22.0 1.2 0.00028 20.6 0.1 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold UPF0565 PF10561.9 CDJ41704.1 - 0.001 18.4 2.9 0.001 18.4 2.9 2.1 1 1 1 2 2 2 1 Uncharacterised protein family UPF0565 FSH1 PF03959.13 CDJ41704.1 - 0.002 17.8 3.4 0.0029 17.3 3.4 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 CDJ41704.1 - 0.017 14.9 0.2 0.041 13.7 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 CDJ41704.1 - 0.028 15.0 4.1 0.045 14.4 3.7 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 CDJ41704.1 - 0.18 11.5 4.0 0.4 10.3 3.2 1.9 1 1 0 1 1 1 0 PGAP1-like protein FAM199X PF15814.5 CDJ41705.1 - 0.26 10.3 2.3 0.34 9.9 2.3 1.1 1 0 0 1 1 1 0 Protein family FAM199X TFIIA PF03153.13 CDJ41705.1 - 0.76 9.7 8.1 0.94 9.4 8.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF3_subunit PF08597.10 CDJ41705.1 - 5 7.0 9.1 6.5 6.6 9.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Profilin PF00235.19 CDJ41706.1 - 1.1e-16 61.2 0.1 1.6e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 Profilin DUF755 PF05501.11 CDJ41707.1 - 0.00029 21.1 1.5 0.00029 21.1 1.5 7.2 5 2 0 5 5 5 1 Domain of unknown function (DUF755) Pkinase PF00069.25 CDJ41707.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain SUIM_assoc PF16619.5 CDJ41708.1 - 1.8 8.7 9.6 0.32 11.1 0.2 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ41708.1 - 3.2 7.3 14.0 6 6.4 14.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ras PF00071.22 CDJ41709.1 - 6.1e-32 110.4 0.3 1.1e-31 109.6 0.0 1.6 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CDJ41709.1 - 1e-28 99.9 0.3 2.8e-28 98.5 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ41709.1 - 3.9e-09 36.2 0.1 6.5e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CDJ41709.1 - 0.00036 20.0 0.7 0.00052 19.5 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDJ41709.1 - 0.0066 16.5 0.1 0.023 14.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ41709.1 - 0.0067 15.8 1.3 0.0092 15.4 0.0 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 CDJ41709.1 - 0.018 14.6 0.6 0.038 13.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 CDJ41709.1 - 0.049 14.0 3.4 0.43 10.9 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 CDJ41709.1 - 0.068 12.7 0.5 0.17 11.4 0.0 1.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Spt20 PF12090.8 CDJ41709.1 - 1.9 8.0 12.7 3 7.4 12.7 1.2 1 0 0 1 1 1 0 Spt20 family SWIRM PF04433.17 CDJ41710.1 - 1.1e-21 77.0 0.0 3.3e-21 75.4 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 CDJ41710.1 - 6.9e-12 45.4 0.0 1.3e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 CDJ41710.1 - 6.4e-10 38.9 9.7 6.4e-10 38.9 9.7 3.4 6 0 0 6 6 6 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 CDJ41710.1 - 6e-07 29.6 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Macoilin PF09726.9 CDJ41710.1 - 9.4 4.6 10.6 1.4 7.4 5.8 1.9 2 0 0 2 2 2 0 Macoilin family MFMR_assoc PF16596.5 CDJ41711.1 - 0.02 15.4 3.2 0.02 15.4 3.2 2.8 1 1 1 2 2 2 0 Disordered region downstream of MFMR Nucleoporin_FG PF13634.6 CDJ41712.1 - 3.6e-15 56.6 133.0 5.3e-07 30.4 27.5 13.2 5 4 5 10 10 10 4 Nucleoporin FG repeat region Ferric_reduct PF01794.19 CDJ41714.1 - 0.0092 16.1 2.0 0.0092 16.1 2.0 2.1 2 1 0 2 2 2 1 Ferric reductase like transmembrane component UCR_UQCRX_QCR9 PF05365.12 CDJ41714.1 - 5.3 7.1 16.2 1.3 9.0 0.8 3.2 2 1 1 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Sedlin_N PF04628.13 CDJ41715.1 - 3.4e-12 46.6 0.0 4.6e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CDJ41715.1 - 0.022 14.7 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 Sybindin-like family zn-ribbon_14 PF16503.5 CDJ41719.1 - 0.13 11.8 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon Collagen PF01391.18 CDJ41720.1 - 9.5 6.1 53.4 3.5e+02 1.0 53.4 2.5 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Helicase_C PF00271.31 CDJ41721.1 - 1.1e-09 38.7 0.0 1.1e-09 38.7 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SUIM_assoc PF16619.5 CDJ41721.1 - 0.012 15.7 2.3 0.012 15.7 2.3 9.3 5 3 2 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 ESSS PF10183.9 CDJ41721.1 - 0.031 14.5 0.4 0.031 14.5 0.4 2.2 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Thymidylat_synt PF00303.19 CDJ41722.1 - 1.1e-98 329.6 0.0 1.5e-98 329.2 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 CDJ41722.1 - 8e-28 97.2 0.0 1.6e-10 40.9 0.0 3.4 3 0 0 3 3 3 3 Dihydrofolate reductase SARAF PF06682.12 CDJ41722.1 - 0.023 14.4 2.8 0.053 13.2 2.8 1.5 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis FAM176 PF14851.6 CDJ41722.1 - 0.066 12.9 0.1 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 FAM176 family ANAPC_CDC26 PF10471.9 CDJ41722.1 - 4.1 8.3 19.8 8.6 7.3 4.0 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF4820 PF16091.5 CDJ41723.1 - 0.0077 15.6 2.5 0.012 15.0 2.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) TFIIA PF03153.13 CDJ41723.1 - 0.071 13.1 7.2 0.093 12.7 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ41723.1 - 0.17 11.8 0.3 0.22 11.5 0.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 CDJ41723.1 - 2.1 9.0 10.2 7 7.3 10.3 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LapA_dom PF06305.11 CDJ41723.1 - 2.9 7.8 5.2 3 7.7 2.7 2.2 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Spt20 PF12090.8 CDJ41723.1 - 5.5 6.5 14.4 7.7 6.0 14.4 1.1 1 0 0 1 1 1 0 Spt20 family DEAD PF00270.29 CDJ41724.1 - 2.1e-50 170.9 0.0 3.4e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ41724.1 - 4.7e-34 117.1 0.0 1.4e-33 115.5 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 CDJ41724.1 - 0.0044 15.9 0.0 0.011 14.5 0.0 1.6 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 CDJ41724.1 - 0.1 12.9 0.0 2.8 8.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain CDV3 PF15359.6 CDJ41724.1 - 0.12 12.9 3.4 0.22 12.0 3.4 1.3 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 V-ATPase_C PF03223.15 CDJ41725.1 - 4.6e-83 279.7 0.0 5.2e-83 279.5 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C SARAF PF06682.12 CDJ41725.1 - 0.22 11.1 1.1 0.33 10.6 1.1 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis ECH_1 PF00378.20 CDJ41726.1 - 3.9e-24 85.3 0.0 5.1e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDJ41726.1 - 4.5e-08 33.0 0.0 5.6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CDC45 PF02724.14 CDJ41727.1 - 0.0019 16.6 28.1 0.002 16.5 28.1 1.0 1 0 0 1 1 1 1 CDC45-like protein Apt1 PF10351.9 CDJ41727.1 - 0.11 11.3 20.8 0.12 11.2 20.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ41727.1 - 0.17 10.6 38.3 0.23 10.2 38.3 1.2 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 CDJ41727.1 - 0.35 10.8 26.1 0.39 10.6 26.1 1.0 1 0 0 1 1 1 0 SPX domain ALMT PF11744.8 CDJ41727.1 - 0.98 8.2 26.3 1.6 7.5 26.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Vac7 PF12751.7 CDJ41727.1 - 1.1 8.6 20.0 1.5 8.2 20.0 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 SLC12 PF03522.15 CDJ41727.1 - 1.2 8.1 37.1 1.5 7.8 37.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Membralin PF09746.9 CDJ41727.1 - 1.8 7.5 23.7 2.2 7.2 23.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein Raftlin PF15250.6 CDJ41727.1 - 2 7.1 25.9 2.3 6.8 25.9 1.0 1 0 0 1 1 1 0 Raftlin DUF4045 PF13254.6 CDJ41727.1 - 2.5 7.7 27.6 2.9 7.5 27.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Sin_N PF04801.13 CDJ41727.1 - 3.3 6.8 46.6 4 6.6 46.6 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Caldesmon PF02029.15 CDJ41727.1 - 3.3 6.3 38.2 4.2 6.0 38.2 1.1 1 0 0 1 1 1 0 Caldesmon LAP1C PF05609.12 CDJ41727.1 - 4.3 6.3 32.7 5 6.1 32.7 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hydin_ADK PF17213.3 CDJ41727.1 - 4.5 7.5 25.7 6.7 6.9 25.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain PAT1 PF09770.9 CDJ41727.1 - 5.4 5.2 57.7 6.2 5.0 57.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.11 CDJ41727.1 - 5.7 5.3 26.6 7.8 4.8 26.6 1.3 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 CDJ41727.1 - 5.7 3.9 31.2 6.1 3.8 31.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AF-4 PF05110.13 CDJ41727.1 - 8 4.4 41.2 9 4.2 41.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 CDJ41727.1 - 9.2 4.7 29.6 16 3.9 29.6 1.3 1 0 0 1 1 1 0 Macoilin family ATP-synt_ab PF00006.25 CDJ41728.1 - 4.8e-60 202.9 0.4 3.2e-59 200.1 0.4 2.0 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDJ41728.1 - 1.5e-18 67.0 1.3 6e-18 65.1 1.3 2.1 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_16 PF13191.6 CDJ41728.1 - 8.2e-05 23.0 0.0 8.2e-05 23.0 0.0 2.3 2 1 0 2 2 1 1 AAA ATPase domain RnfC_N PF13375.6 CDJ41728.1 - 0.00076 19.4 2.2 0.0033 17.3 0.7 2.4 3 0 0 3 3 2 1 RnfC Barrel sandwich hybrid domain NB-ARC PF00931.22 CDJ41728.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2722 PF10846.8 CDJ41728.1 - 0.014 14.4 3.9 0.48 9.3 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) AAA PF00004.29 CDJ41728.1 - 0.023 15.1 0.2 0.39 11.2 0.2 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CDJ41728.1 - 0.068 12.5 1.5 0.095 12.0 0.1 2.0 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.6 CDJ41728.1 - 0.095 12.3 0.4 0.25 10.9 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDJ41728.1 - 0.099 12.9 1.0 0.14 12.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 CDJ41728.1 - 0.099 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 CDJ41728.1 - 0.1 13.1 1.1 0.14 12.7 0.0 1.7 2 0 0 2 2 2 0 ABC transporter TFIIA PF03153.13 CDJ41728.1 - 0.15 12.1 13.1 1.6 8.7 5.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NACHT PF05729.12 CDJ41728.1 - 0.16 11.9 1.9 0.17 11.8 0.2 2.0 2 1 0 2 2 2 0 NACHT domain SUIM_assoc PF16619.5 CDJ41728.1 - 0.16 12.1 22.1 0.83 9.8 5.2 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4746 PF15928.5 CDJ41728.1 - 0.19 11.1 0.4 0.41 10.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Spt20 PF12090.8 CDJ41728.1 - 0.67 9.5 16.5 2.3 7.7 5.8 2.1 2 0 0 2 2 2 0 Spt20 family Ribosomal_60s PF00428.19 CDJ41729.1 - 0.031 14.9 2.8 0.031 14.9 2.8 3.7 2 1 1 3 3 3 0 60s Acidic ribosomal protein ESM4 PF15952.5 CDJ41729.1 - 0.13 12.7 29.6 0.15 12.5 16.2 2.2 2 0 0 2 2 2 0 Enhancer of split M4 family Peptidase_S15 PF02129.18 CDJ41729.1 - 1.4 8.4 22.7 0.16 11.5 3.7 2.4 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) XAP5 PF04921.14 CDJ41729.1 - 6.1 6.6 13.4 7 6.4 0.1 2.4 2 0 0 2 2 2 0 XAP5, circadian clock regulator DUF1732 PF08340.11 CDJ41731.1 - 0.0075 16.2 0.6 0.0094 15.9 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1732) Lysyl_oxidase PF01186.17 CDJ41731.1 - 0.055 13.1 0.2 0.057 13.1 0.2 1.0 1 0 0 1 1 1 0 Lysyl oxidase SOG2 PF10428.9 CDJ41732.1 - 0.96 8.6 19.0 0.97 8.6 19.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 CDJ41732.1 - 2.1 7.0 7.3 2.6 6.7 7.3 1.1 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 CDJ41732.1 - 4.7 7.0 23.5 6 6.7 23.5 1.1 1 0 0 1 1 1 0 SPX domain DDHD PF02862.17 CDJ41734.1 - 0.008 16.4 4.8 0.21 11.7 0.4 2.2 2 0 0 2 2 2 2 DDHD domain TFIIA PF03153.13 CDJ41734.1 - 0.012 15.6 2.7 0.012 15.6 2.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TPPII_N PF12583.8 CDJ41734.1 - 0.015 15.9 0.2 0.015 15.9 0.2 3.3 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal DUF3173 PF11372.8 CDJ41734.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) Ctr PF04145.15 CDJ41734.1 - 0.11 13.1 3.1 7.4 7.2 0.1 2.3 2 0 0 2 2 2 0 Ctr copper transporter family Plasmodium_Vir PF05795.11 CDJ41734.1 - 0.29 10.5 4.8 0.5 9.7 0.1 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Apt1 PF10351.9 CDJ41734.1 - 0.31 9.9 9.9 0.35 9.7 0.7 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Dsh_C PF12316.8 CDJ41734.1 - 0.74 10.2 25.6 1.3 9.4 6.2 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Neur_chan_memb PF02932.16 CDJ41734.1 - 0.88 9.6 3.1 2.5 8.1 0.1 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CDJ41734.1 - 1.1 9.1 4.9 0.62 9.8 0.5 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Presenilin PF01080.17 CDJ41734.1 - 1.7 7.3 11.1 0.22 10.2 1.4 2.1 2 0 0 2 2 2 0 Presenilin SR-25 PF10500.9 CDJ41734.1 - 3.4 7.2 30.7 2.8 7.5 14.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ41734.1 - 4.3 7.5 21.4 0.087 12.9 9.2 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF4228 PF14009.6 CDJ41734.1 - 8.3 6.8 18.0 0.089 13.2 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4228) Macoilin PF09726.9 CDJ41734.1 - 8.4 4.8 12.5 4.3 5.8 3.4 2.1 2 0 0 2 2 2 0 Macoilin family MID_MedPIWI PF18296.1 CDJ41735.1 - 0.017 14.9 1.1 0.018 14.8 1.1 1.1 1 0 0 1 1 1 0 MID domain of medPIWI eIF_4EBP PF05456.11 CDJ41735.1 - 0.074 13.0 2.3 0.11 12.4 2.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CobT PF06213.12 CDJ41735.1 - 0.16 11.4 6.2 0.2 11.0 6.2 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT K_channel_TID PF07941.11 CDJ41735.1 - 0.2 12.2 3.6 0.24 11.9 3.6 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Protamine_P2 PF00841.19 CDJ41735.1 - 0.23 11.9 3.3 0.3 11.6 3.3 1.2 1 0 0 1 1 1 0 Sperm histone P2 TFIIA PF03153.13 CDJ41735.1 - 0.35 10.8 10.1 0.37 10.7 10.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 CDJ41735.1 - 1.2 8.3 11.9 1.3 8.2 11.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TPR_16 PF13432.6 CDJ41737.1 - 0.0087 16.7 7.0 0.0087 16.7 7.0 10.2 11 2 1 12 12 12 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ41737.1 - 0.43 10.8 12.9 0.51 10.6 0.1 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 CDJ41738.1 - 0.0019 18.2 0.0 1.6 8.9 4.0 2.8 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Memo PF01875.17 CDJ41739.1 - 8.6e-40 136.6 0.0 1.1e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Ribosomal_L27A PF00828.19 CDJ41740.1 - 6.9e-19 68.8 0.0 6.9e-19 68.8 0.0 2.9 3 2 0 3 3 3 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TFIIA PF03153.13 CDJ41740.1 - 0.0045 17.0 13.1 0.0045 17.0 13.1 1.5 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Seryl_tRNA_N PF02403.22 CDJ41740.1 - 0.0051 17.0 2.4 0.015 15.5 2.4 1.8 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 CDJ41740.1 - 0.025 14.6 1.2 0.05 13.7 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SLX9 PF15341.6 CDJ41740.1 - 0.052 13.9 3.6 0.099 13.0 3.6 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF2333 PF10095.9 CDJ41740.1 - 0.22 10.5 4.2 0.37 9.8 4.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Cob_adeno_trans PF01923.18 CDJ41740.1 - 1.6 8.8 5.2 3.3 7.8 5.1 1.8 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Coatomer_b_Cpla PF14806.6 CDJ41741.1 - 1.7e-33 115.3 0.0 2.5e-16 59.8 0.0 2.5 1 1 1 2 2 2 2 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 CDJ41741.1 - 1.9e-29 102.3 0.0 5.2e-29 101.0 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Adaptin_N PF01602.20 CDJ41741.1 - 1.1e-07 30.8 0.2 2.2e-07 29.8 0.2 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Transposase_24 PF03004.14 CDJ41741.1 - 0.75 9.9 5.6 0.7 10.0 1.4 2.6 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) DUF3446 PF11928.8 CDJ41741.1 - 3.9 7.8 39.5 0.046 14.0 6.0 5.0 5 0 0 5 5 5 0 Early growth response N-terminal domain IMUP PF15761.5 CDJ41741.1 - 9 7.0 30.7 0.26 12.0 3.7 3.9 3 0 0 3 3 3 0 Immortalisation up-regulated protein Spt20 PF12090.8 CDJ41742.1 - 0.26 10.9 28.1 0.46 10.0 28.1 1.4 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ41742.1 - 3.1 7.7 52.5 4.4 7.2 52.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ41742.1 - 4.9 6.6 13.1 7.9 5.9 13.1 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist V_ATPase_I PF01496.19 CDJ41742.1 - 7.4 4.3 8.4 9.2 4.0 8.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Smg8_Smg9 PF10220.9 CDJ41742.1 - 8.5 4.5 15.2 12 4.0 15.2 1.2 1 0 0 1 1 1 0 Smg8_Smg9 BORG_CEP PF14957.6 CDJ41742.1 - 9 7.5 10.3 20 6.3 10.3 1.6 1 0 0 1 1 1 0 Cdc42 effector Spt20 PF12090.8 CDJ41743.1 - 0.0033 17.1 13.4 0.0049 16.5 13.4 1.3 1 0 0 1 1 1 1 Spt20 family DUF4175 PF13779.6 CDJ41743.1 - 0.0084 14.1 12.3 0.0097 13.9 12.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) DDHD PF02862.17 CDJ41743.1 - 0.014 15.5 3.1 0.017 15.3 3.1 1.2 1 0 0 1 1 1 0 DDHD domain EPL1 PF10513.9 CDJ41743.1 - 0.019 15.4 4.8 0.025 15.0 4.8 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Lin-8 PF03353.15 CDJ41743.1 - 0.02 14.4 7.8 0.023 14.3 7.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist eIF3_p135 PF12807.7 CDJ41743.1 - 0.021 14.8 2.4 0.03 14.3 2.4 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 eIF-3_zeta PF05091.12 CDJ41743.1 - 0.03 13.3 6.3 0.037 13.0 6.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Bac_rhamnosid_N PF08531.10 CDJ41743.1 - 0.059 13.2 0.8 0.083 12.7 0.8 1.2 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Pex14_N PF04695.13 CDJ41743.1 - 0.061 14.0 10.7 0.13 12.9 10.7 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CDJ41743.1 - 0.068 11.9 5.1 0.07 11.9 5.1 1.1 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 CDJ41743.1 - 0.098 12.6 8.0 0.15 12.0 8.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4667 PF15700.5 CDJ41743.1 - 0.53 10.4 5.9 0.67 10.0 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Hydin_ADK PF17213.3 CDJ41743.1 - 1.4 9.2 8.7 2.2 8.5 8.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain ALMT PF11744.8 CDJ41743.1 - 3.4 6.4 7.4 4.5 6.0 7.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter GramPos_pilinD1 PF16555.5 CDJ41743.1 - 3.6 7.7 10.1 3.5 7.8 8.8 1.6 1 1 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain Neur_chan_memb PF02932.16 CDJ41743.1 - 4.1 7.4 5.7 5.7 6.9 5.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ETRAMP PF09716.10 CDJ41744.1 - 1.9 8.6 3.7 16 5.7 0.0 2.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF1223 PF06764.11 CDJ41744.1 - 4 7.4 11.1 0.36 10.8 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1223) Rhomboid PF01694.22 CDJ41745.1 - 1.1e-26 93.6 11.5 1.1e-26 93.6 11.5 1.8 2 0 0 2 2 2 1 Rhomboid family DUF192 PF02643.15 CDJ41746.1 - 0.00036 20.6 0.0 0.00052 20.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 MreC PF04085.14 CDJ41746.1 - 0.11 12.4 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 rod shape-determining protein MreC SH3_7 PF12914.7 CDJ41746.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 SH3 domain of SH3b2 type Ribosomal_S8e PF01201.22 CDJ41747.1 - 1.3e-52 177.6 0.3 1.5e-52 177.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e HEPN_AbiV PF18728.1 CDJ41748.1 - 0.15 12.2 1.4 0.37 10.9 1.4 1.6 1 0 0 1 1 1 0 AbiV NUMOD1 PF07453.13 CDJ41748.1 - 0.24 11.7 0.0 0.79 10.1 0.0 1.9 2 0 0 2 2 2 0 NUMOD1 domain YqzM PF14141.6 CDJ41751.1 - 0.53 10.4 2.6 0.89 9.6 2.6 1.3 1 0 0 1 1 1 0 YqzM-like protein BAF1_ABF1 PF04684.13 CDJ41751.1 - 8.9 5.2 39.6 3 6.8 24.0 2.0 1 1 1 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Sas10_Utp3 PF04000.15 CDJ41752.1 - 2.1e-08 34.6 0.0 2.1e-08 34.6 0.0 2.7 2 1 0 2 2 2 1 Sas10/Utp3/C1D family DUF4558 PF15104.6 CDJ41752.1 - 0.017 15.2 6.5 0.034 14.2 6.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) Apo-CIII PF05778.12 CDJ41752.1 - 0.05 13.3 0.2 0.14 11.8 0.2 1.7 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) RAP1 PF07218.11 CDJ41752.1 - 0.44 8.8 12.2 0.57 8.4 12.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDK2AP PF09806.9 CDJ41752.1 - 0.64 10.1 23.0 0.15 12.1 13.5 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Cwf_Cwc_15 PF04889.12 CDJ41753.1 - 3.2e-38 131.9 4.3 3.6e-38 131.7 4.3 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein End3 PF12761.7 CDJ41753.1 - 0.023 14.9 3.9 0.036 14.2 3.9 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Pex14_N PF04695.13 CDJ41754.1 - 0.076 13.7 0.2 0.076 13.7 0.2 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 CDJ41754.1 - 1.2 8.8 6.5 4.1 7.1 5.9 2.0 2 0 0 2 2 2 0 Connexin U79_P34 PF03064.16 CDJ41754.1 - 2.9 7.2 12.3 25 4.2 9.3 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 S1 PF00575.23 CDJ41757.1 - 1.3e-05 25.5 0.0 3.7 8.0 0.0 5.8 6 0 0 6 6 6 2 S1 RNA binding domain Cna_B PF05738.13 CDJ41757.1 - 0.12 12.9 2.5 0.61 10.7 2.5 2.2 1 0 0 1 1 1 0 Cna protein B-type domain KASH PF10541.9 CDJ41758.1 - 0.089 13.1 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 Nuclear envelope localisation domain AF-4 PF05110.13 CDJ41758.1 - 1.7 6.6 7.0 2.3 6.2 7.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ribosomal_60s PF00428.19 CDJ41758.1 - 3.6 8.3 24.4 0.094 13.3 9.6 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein NPR1_interact PF15699.5 CDJ41759.1 - 0.044 14.4 9.1 0.053 14.1 9.1 1.1 1 0 0 1 1 1 0 NPR1 interacting Phostensin_N PF13916.6 CDJ41759.1 - 0.048 14.0 0.8 0.048 14.0 0.8 2.4 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Hydin_ADK PF17213.3 CDJ41759.1 - 1.2 9.4 9.5 1.3 9.3 9.5 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RR_TM4-6 PF06459.12 CDJ41759.1 - 2.5 7.8 11.0 2.7 7.8 11.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ41759.1 - 5.6 6.9 10.0 6.1 6.8 10.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 CDJ41759.1 - 7.1 5.9 12.0 7.9 5.7 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 CDJ41759.1 - 7.2 6.5 32.2 8.8 6.2 32.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ41759.1 - 8.4 5.0 12.8 8.9 5.0 12.8 1.0 1 0 0 1 1 1 0 Presenilin BT1 PF03092.16 CDJ41760.1 - 2.1e-77 260.6 20.8 8.3e-54 182.7 7.8 2.1 2 0 0 2 2 2 2 BT1 family AMPK1_CBM PF16561.5 CDJ41761.1 - 0.043 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase DUF3306 PF11748.8 CDJ41761.1 - 2.6 9.0 14.8 4.7 8.1 4.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) zf-CCCH PF00642.24 CDJ41762.1 - 5.3e-08 32.6 17.3 4.8e-06 26.3 0.7 4.2 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ41762.1 - 1.2e-05 25.2 18.7 0.024 14.7 0.5 3.8 4 0 0 4 4 4 3 Zinc finger domain Torus PF16131.5 CDJ41762.1 - 1.3e-05 25.9 7.1 0.032 14.9 0.0 3.6 3 1 0 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 CDJ41762.1 - 0.016 15.0 14.2 0.054 13.3 0.9 3.8 4 0 0 4 4 4 0 CCCH-type zinc finger Peptidase_S51 PF03575.17 CDJ41762.1 - 0.02 14.6 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 zf-CCCH_3 PF15663.5 CDJ41762.1 - 0.16 12.2 7.8 0.057 13.6 3.2 2.3 2 0 0 2 2 2 0 Zinc-finger containing family Neur_chan_memb PF02932.16 CDJ41763.1 - 7.9 6.5 6.5 4.7 7.2 4.2 1.8 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RRM_1 PF00076.22 CDJ41764.1 - 1.6e-19 69.4 0.0 1.9e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PepSY_TM PF03929.16 CDJ41765.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 PepSY-associated TM region Col_cuticle_N PF01484.17 CDJ41765.1 - 0.17 12.0 0.3 0.42 10.7 0.3 1.7 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain DUF349 PF03993.12 CDJ41765.1 - 0.17 12.2 2.6 3.6 8.0 1.1 3.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) SesA PF17107.5 CDJ41765.1 - 0.19 11.9 3.3 4.2 7.6 0.1 2.8 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DASH_Duo1 PF08651.10 CDJ41765.1 - 2.2 8.1 5.9 12 5.7 1.2 3.6 3 0 0 3 3 3 0 DASH complex subunit Duo1 Flu_M1_C PF08289.11 CDJ41766.1 - 4.2 7.6 7.3 38 4.6 0.3 3.1 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain CM_2 PF01817.21 CDJ41766.1 - 6.2 7.3 12.0 0.42 11.0 0.2 4.3 3 2 2 6 6 6 0 Chorismate mutase type II DUF3037 PF11236.8 CDJ41766.1 - 7.4 7.0 7.6 4.4 7.8 0.0 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF3037) MnmE_helical PF12631.7 CDJ41766.1 - 7.6 6.6 12.5 5.2 7.2 0.2 3.2 3 0 0 3 3 3 0 MnmE helical domain FRB_dom PF08771.11 CDJ41767.1 - 0.18 12.2 4.3 0.25 11.8 1.8 2.5 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain RRF_GI PF12614.8 CDJ41767.1 - 0.45 10.7 2.9 20 5.4 0.3 3.3 2 1 1 3 3 3 0 Ribosome recycling factor V-SNARE PF05008.15 CDJ41767.1 - 1 9.8 9.9 6.1 7.3 0.1 4.3 4 0 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Hpt PF01627.23 CDJ41767.1 - 2.2 8.6 8.9 2.7 8.3 0.1 4.1 3 0 0 3 3 3 0 Hpt domain MFS_2 PF13347.6 CDJ41768.1 - 2.3e-42 145.1 12.0 3.2e-42 144.6 12.0 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein ubiquitin PF00240.23 CDJ41768.1 - 5.8e-19 67.6 0.0 1.2e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family MFS_1 PF07690.16 CDJ41768.1 - 2e-07 30.3 22.8 2e-07 30.3 22.8 2.2 2 1 0 2 2 1 1 Major Facilitator Superfamily Rad60-SLD PF11976.8 CDJ41768.1 - 5.8e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SUIM_assoc PF16619.5 CDJ41768.1 - 0.00035 20.6 5.4 0.00035 20.6 5.4 1.7 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Rad60-SLD_2 PF13881.6 CDJ41768.1 - 0.00048 20.2 0.5 0.00085 19.4 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDJ41768.1 - 0.0012 19.4 0.3 0.0027 18.2 0.3 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 CDJ41768.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 CDJ41768.1 - 0.042 14.3 0.0 0.089 13.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Spt20 PF12090.8 CDJ41768.1 - 0.46 10.1 8.9 0.78 9.3 8.9 1.3 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ41768.1 - 0.58 9.2 1.5 0.98 8.5 1.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 CDJ41768.1 - 6.8 6.6 10.8 11 5.9 10.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PCI PF01399.27 CDJ41769.1 - 4e-09 36.9 0.1 1.5e-08 35.1 0.2 1.9 2 0 0 2 2 2 1 PCI domain TPR_14 PF13428.6 CDJ41769.1 - 0.033 15.0 2.1 0.36 11.8 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CLTH PF10607.9 CDJ41769.1 - 0.039 13.8 0.3 2 8.3 0.3 2.6 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain TPR_5 PF12688.7 CDJ41769.1 - 0.045 14.0 0.1 1.2 9.4 0.0 2.9 2 1 1 3 3 3 0 Tetratrico peptide repeat TPR_1 PF00515.28 CDJ41769.1 - 0.18 11.6 0.3 0.49 10.3 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat eIF3m_C_helix PF18005.1 CDJ41769.1 - 5.7 6.7 9.9 0.094 12.4 2.7 1.8 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix PPP4R2 PF09184.11 CDJ41770.1 - 1.3e-05 25.0 6.8 1.3e-05 25.0 6.8 2.4 2 1 0 2 2 2 1 PPP4R2 SUIM_assoc PF16619.5 CDJ41770.1 - 0.0038 17.3 0.4 0.0038 17.3 0.4 4.7 4 1 0 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ41770.1 - 0.014 15.1 25.3 0.3 10.7 11.3 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Dsh_C PF12316.8 CDJ41770.1 - 1.9 8.8 29.8 2.9 8.2 14.5 2.5 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal LAG1-DNAbind PF09271.11 CDJ41770.1 - 3.3 8.3 13.5 1.2 9.8 2.3 2.3 2 0 0 2 2 2 0 LAG1, DNA binding Hexokinase_1 PF00349.21 CDJ41772.1 - 3.6e-57 193.5 0.0 7.1e-57 192.5 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Hexokinase_2 PF03727.16 CDJ41772.1 - 1.7e-49 168.4 0.0 2.7e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase VanY PF02557.17 CDJ41772.1 - 0.0043 16.9 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase DUF2572 PF10833.8 CDJ41772.1 - 0.56 9.9 2.4 0.87 9.3 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) DUF2009 PF09418.10 CDJ41773.1 - 8.8e-160 532.7 0.0 1.6e-91 307.7 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2009) Corona_nucleoca PF00937.18 CDJ41773.1 - 2.9 6.8 16.0 0.82 8.6 10.5 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DUF4366 PF14283.6 CDJ41774.1 - 0.65 10.0 4.1 0.94 9.5 4.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) TMEM51 PF15345.6 CDJ41775.1 - 0.00031 20.7 0.1 0.00037 20.4 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 BatD PF13584.6 CDJ41775.1 - 0.0015 17.4 0.1 0.002 17.0 0.1 1.1 1 0 0 1 1 1 1 Oxygen tolerance OAD_gamma PF04277.13 CDJ41775.1 - 0.014 16.0 0.0 0.033 14.8 0.0 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TssO PF17561.2 CDJ41775.1 - 0.033 14.3 0.0 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO Cadherin_C_2 PF16492.5 CDJ41775.1 - 0.041 14.6 0.2 0.097 13.4 0.1 1.7 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 CDJ41775.1 - 0.061 14.2 0.0 0.13 13.1 0.0 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2448 PF10476.9 CDJ41775.1 - 0.11 12.4 1.7 0.13 12.1 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2448) DUF4834 PF16118.5 CDJ41775.1 - 0.26 12.3 0.1 0.26 12.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) COX15-CtaA PF02628.15 CDJ41776.1 - 1.1e-30 106.9 1.9 1.2e-30 106.7 1.9 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Ribosomal_60s PF00428.19 CDJ41776.1 - 0.086 13.4 7.6 0.12 12.9 7.6 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF773 PF05600.12 CDJ41777.1 - 2.3e-38 132.2 36.7 3.3e-37 128.4 30.9 3.1 2 2 0 2 2 2 2 CDK5 regulatory subunit-associated protein 3 Androgen_recep PF02166.16 CDJ41777.1 - 0.0035 16.3 6.8 0.0035 16.3 6.8 5.4 4 2 2 6 6 6 1 Androgen receptor IMUP PF15761.5 CDJ41777.1 - 2.1 9.1 6.4 3.9 8.2 1.8 2.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein EF-hand_1 PF00036.32 CDJ41778.1 - 3.1e-22 76.4 9.4 5e-08 31.9 1.8 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CDJ41778.1 - 8e-20 71.1 6.8 8e-15 55.1 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ41778.1 - 8.7e-19 65.8 6.2 1.3e-05 24.8 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CDJ41778.1 - 1.6e-14 53.5 7.2 5.2e-11 42.2 0.8 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 CDJ41778.1 - 9.3e-10 38.7 0.3 1.6e-06 28.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ41778.1 - 2.4e-09 36.2 6.3 4e-06 26.1 0.8 3.3 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 CDJ41778.1 - 0.0036 17.1 3.4 0.0041 16.9 0.2 2.1 2 0 0 2 2 2 1 EF hand SHOCT PF09851.9 CDJ41778.1 - 0.0096 15.6 1.2 0.79 9.5 0.1 3.0 2 0 0 2 2 2 1 Short C-terminal domain Staphylokinase PF02821.16 CDJ41778.1 - 0.01 16.3 0.3 0.028 14.9 0.1 1.6 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family EF-hand_4 PF12763.7 CDJ41778.1 - 0.022 14.7 1.8 0.41 10.6 0.7 2.5 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand MgtE_N PF03448.17 CDJ41778.1 - 0.074 13.7 2.0 0.087 13.4 1.3 1.5 2 0 0 2 2 1 0 MgtE intracellular N domain RST PF12174.8 CDJ41778.1 - 0.095 12.6 0.2 1.4 8.9 0.0 2.4 1 1 2 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain DUF1636 PF07845.11 CDJ41778.1 - 0.17 12.4 0.0 2.8 8.4 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1636) PhetRS_B1 PF18262.1 CDJ41778.1 - 0.22 11.8 2.9 0.29 11.4 0.4 2.2 1 1 2 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain IMUP PF15761.5 CDJ41779.1 - 0.05 14.3 2.0 0.19 12.4 2.0 2.0 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF2458 PF10454.9 CDJ41779.1 - 2.4 7.8 8.7 0.96 9.1 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2458) Prominin PF05478.11 CDJ41780.1 - 1.7 6.5 3.4 1.3 6.8 1.3 1.7 2 0 0 2 2 2 0 Prominin Laminin_II PF06009.12 CDJ41780.1 - 4.1 7.4 20.1 1.4 9.0 0.6 4.4 4 1 0 4 4 4 0 Laminin Domain II PSD1 PF07587.11 CDJ41782.1 - 0.029 13.9 5.5 0.095 12.2 5.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1553) DUF3774 PF12609.8 CDJ41782.1 - 2.4 9.2 4.8 13 6.9 0.0 4.0 3 1 0 3 3 3 0 Wound-induced protein Com_YlbF PF06133.11 CDJ41782.1 - 9.7 6.9 14.0 23 5.6 1.2 4.1 4 1 0 4 4 4 0 Control of competence regulator ComK, YlbF/YmcA MBF1 PF08523.10 CDJ41784.1 - 3.5e-19 69.0 0.8 3.5e-19 69.0 0.8 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CDJ41784.1 - 8.2e-15 54.6 0.1 1.3e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 CDJ41784.1 - 6.1e-07 29.4 0.1 1.5e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 CDJ41784.1 - 8.7e-07 29.2 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 CDJ41784.1 - 0.00027 21.3 0.0 0.00048 20.5 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 CDJ41784.1 - 0.012 15.6 0.1 0.027 14.4 0.1 1.6 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 CDJ41784.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_25 PF13413.6 CDJ41784.1 - 0.04 13.8 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 CDJ41784.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding UPF0203 PF05254.12 CDJ41785.1 - 0.0018 18.5 0.0 0.0018 18.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.13 CDJ41785.1 - 0.083 13.0 0.6 0.093 12.9 0.6 1.1 1 0 0 1 1 1 0 CHCH domain Transketolase_N PF00456.21 CDJ41786.1 - 7.5e-144 478.8 0.0 1.1e-143 478.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CDJ41786.1 - 8e-37 126.6 0.0 1.3e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDJ41786.1 - 3.7e-05 23.6 0.0 8.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CDJ41786.1 - 0.00045 19.5 0.0 0.00078 18.7 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 CDJ41786.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Retrotrans_gag PF03732.17 CDJ41788.1 - 0.0029 17.8 0.0 0.021 15.1 0.0 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein TPR_12 PF13424.6 CDJ41791.1 - 0.00088 19.5 3.2 0.32 11.3 0.2 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat Mob1_phocein PF03637.17 CDJ41792.1 - 4.4e-32 111.4 0.0 6.1e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family NopRA1 PF16201.5 CDJ41792.1 - 0.13 11.8 3.9 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 Methyltransf_16 PF10294.9 CDJ41793.1 - 4.3e-05 23.3 0.0 7.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase BEX PF04538.12 CDJ41793.1 - 0.14 12.8 10.3 0.24 12.0 10.3 1.4 1 0 0 1 1 1 0 Brain expressed X-linked like family ubiquitin PF00240.23 CDJ41794.1 - 0 1187.5 0.0 2.5e-08 33.6 0.0 41.0 1 1 40 41 41 41 41 Ubiquitin family Ubiquitin_2 PF14560.6 CDJ41794.1 - 1.7e-89 294.4 0.1 6.9 7.2 0.0 40.7 41 0 0 41 41 41 39 Ubiquitin-like domain DUF2407 PF10302.9 CDJ41794.1 - 6.6e-87 286.9 10.0 9.3 6.9 0.0 39.6 1 1 39 40 40 40 37 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 CDJ41794.1 - 9.9e-83 272.0 0.0 0.4 10.5 0.0 38.5 1 1 39 40 40 40 40 Ubiquitin-2 like Rad60 SUMO-like Pr_beta_C PF12465.8 CDJ41794.1 - 1.1e-48 162.2 0.0 80 2.8 0.0 38.3 41 0 0 41 41 41 0 Proteasome beta subunits C terminal Rad60-SLD_2 PF13881.6 CDJ41794.1 - 9.7e-45 151.2 2.6 35 4.5 0.0 30.8 1 1 38 39 39 39 0 Ubiquitin-2 like Rad60 SUMO-like DUF4850 PF16142.5 CDJ41794.1 - 5.4e-19 68.4 4.6 14 5.1 0.0 17.5 1 1 31 33 33 33 1 Domain of unknown function (DUF4850) Androgen_recep PF02166.16 CDJ41795.1 - 0.0038 16.1 1.9 0.0038 16.1 1.9 2.2 2 0 0 2 2 2 1 Androgen receptor DUF247 PF03140.15 CDJ41795.1 - 0.13 11.5 0.2 0.19 10.9 0.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function DUF3645 PF12359.8 CDJ41796.1 - 6.9e-16 57.3 0.1 1.3e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_7 PF13499.6 CDJ41796.1 - 2.3e-05 24.8 0.0 4.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ41796.1 - 4.4e-05 23.1 0.1 0.38 10.8 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CDJ41796.1 - 9.7e-05 21.7 0.1 0.005 16.3 0.1 2.5 2 0 0 2 2 2 1 EF hand RskA PF10099.9 CDJ41796.1 - 0.00055 20.3 7.0 0.00055 20.3 7.0 8.2 6 3 0 7 7 7 3 Anti-sigma-K factor rskA EF-hand_8 PF13833.6 CDJ41796.1 - 0.0028 17.4 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair Vps62 PF06101.11 CDJ41796.1 - 0.11 10.7 0.0 0.2 9.9 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 62 RskA PF10099.9 CDJ41797.1 - 0.012 15.9 10.6 0.012 15.9 10.6 8.7 2 2 3 6 6 6 0 Anti-sigma-K factor rskA Acid_PPase PF12689.7 CDJ41798.1 - 0.18 11.7 1.1 1.9 8.3 0.0 3.3 2 1 0 2 2 2 0 Acid Phosphatase DEAD PF00270.29 CDJ41799.1 - 3.7e-44 150.6 1.0 1e-43 149.2 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ41799.1 - 5.5e-30 104.0 1.3 1.8e-29 102.3 0.4 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 CDJ41799.1 - 6.9e-06 25.9 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ41799.1 - 1.7e-05 24.9 0.0 3.6e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA-synt_1b PF00579.25 CDJ41799.1 - 0.0015 17.9 0.0 0.0034 16.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CMS1 PF14617.6 CDJ41799.1 - 0.0025 17.2 0.2 0.026 13.9 0.0 2.3 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 CDJ41799.1 - 0.0055 16.6 0.1 0.019 14.8 0.0 2.0 2 1 0 2 2 2 1 Helicase AAA_22 PF13401.6 CDJ41799.1 - 0.072 13.4 0.5 0.58 10.4 0.5 2.5 1 1 0 1 1 1 0 AAA domain PapG_C PF03628.13 CDJ41799.1 - 0.14 12.1 0.0 8.5 6.3 0.0 2.6 3 0 0 3 3 3 0 PapG chaperone-binding domain TB2_DP1_HVA22 PF03134.19 CDJ41800.1 - 3.6e-26 90.9 8.3 5e-26 90.4 8.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Collagen PF01391.18 CDJ41800.1 - 1.7 8.5 17.6 0.27 11.0 13.6 1.7 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) eIF3_p135 PF12807.7 CDJ41801.1 - 3.5e-14 53.2 0.0 3.5e-14 53.2 0.0 4.1 4 0 0 4 4 4 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.6 CDJ41801.1 - 7.3e-08 32.5 0.1 2.8e-06 27.3 0.1 2.7 1 1 0 1 1 1 1 Clustered mitochondria DUF727 PF05303.12 CDJ41801.1 - 0.016 15.3 0.0 0.88 9.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF727) Zip PF02535.22 CDJ41801.1 - 1.9 7.6 10.5 6.3 5.9 10.5 1.9 1 0 0 1 1 1 0 ZIP Zinc transporter Otopetrin PF03189.13 CDJ41801.1 - 4.5 6.0 8.2 1 8.1 3.7 2.2 2 0 0 2 2 2 0 Otopetrin ELM2 PF01448.24 CDJ41802.1 - 0.01 16.5 0.1 0.028 15.2 0.1 1.7 1 0 0 1 1 1 0 ELM2 domain TFIIA PF03153.13 CDJ41802.1 - 0.13 12.2 14.1 0.16 11.9 14.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rad60-SLD_2 PF13881.6 CDJ41803.1 - 0.00072 19.6 0.0 0.00092 19.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Gp37 PF09646.10 CDJ41803.1 - 0.04 13.8 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Gp37 protein DUF2407 PF10302.9 CDJ41803.1 - 0.066 13.8 0.0 0.3 11.7 0.0 1.8 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain DUF5067 PF16729.5 CDJ41803.1 - 0.071 13.0 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5067) Ldh_1_N PF00056.23 CDJ41804.1 - 1.3e-36 125.8 0.2 2.4e-36 124.9 0.2 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CDJ41804.1 - 5.2e-31 107.8 0.0 7.3e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 CDJ41804.1 - 3e-05 23.7 0.7 0.0008 19.0 0.1 2.5 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase DUF2336 PF10098.9 CDJ41804.1 - 0.021 14.3 0.2 0.051 13.0 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) 3Beta_HSD PF01073.19 CDJ41804.1 - 0.024 13.7 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HTH_31 PF13560.6 CDJ41804.1 - 0.041 14.2 1.6 0.061 13.7 0.2 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain F420_oxidored PF03807.17 CDJ41804.1 - 0.99 10.0 4.4 3.7 8.2 1.3 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent IMP2_N PF18590.1 CDJ41805.1 - 3.5e-15 56.3 0.0 6.7e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain COX6B PF02297.17 CDJ41806.1 - 3e-05 24.2 4.6 4.5e-05 23.6 4.6 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UTRA PF07702.13 CDJ41806.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.4 2 0 0 2 2 2 0 UTRA domain DUF627 PF04781.12 CDJ41806.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF627) PDZ_3 PF17815.1 CDJ41808.1 - 7e-35 120.0 0.0 1.2e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 CDJ41808.1 - 2.5e-19 70.7 1.2 6.7e-19 69.3 1.2 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CDJ41808.1 - 5.2e-11 42.8 0.0 1.3e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 CDJ41808.1 - 0.00072 19.4 0.1 0.33 10.8 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CDJ41808.1 - 0.047 14.0 0.1 3.3 8.1 0.0 3.2 4 0 0 4 4 4 0 PDZ domain Tricorn_PDZ PF14685.6 CDJ41808.1 - 0.11 12.4 0.0 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain Med4 PF10018.9 CDJ41809.1 - 0.00098 18.9 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF1604 PF07713.13 CDJ41810.1 - 3.7e-10 39.5 1.0 3.7e-10 39.5 1.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) SH3-WW_linker PF16618.5 CDJ41810.1 - 0.03 14.8 2.3 0.26 11.7 0.4 2.2 2 0 0 2 2 2 0 Linker region between SH3 and WW domains on ARHGAP12 DUF3035 PF11233.8 CDJ41810.1 - 1.5 9.1 13.4 1.8 8.9 11.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3035) Methyltransf_25 PF13649.6 CDJ41812.1 - 6.4e-12 46.0 0.1 2.9e-11 43.9 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ41812.1 - 2.9e-10 40.2 0.1 9.8e-10 38.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CDJ41812.1 - 5.1e-10 39.2 0.0 8.5e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CDJ41812.1 - 1.5e-09 38.3 0.1 7.5e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ41812.1 - 2.8e-05 24.0 0.0 8.5e-05 22.4 0.0 1.7 1 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CDJ41812.1 - 0.0001 21.7 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CDJ41812.1 - 0.00022 20.8 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 CDJ41812.1 - 0.0031 17.5 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CDJ41812.1 - 0.0035 16.3 0.0 0.0087 15.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 CDJ41812.1 - 0.0043 16.4 0.0 0.021 14.1 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 CDJ41812.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DOT1 PF08123.13 CDJ41812.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 CDJ41812.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 CDJ41812.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.16 CDJ41812.1 - 0.032 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_18 PF12847.7 CDJ41812.1 - 0.033 14.1 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ41812.1 - 0.034 14.9 0.0 0.073 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 CDJ41812.1 - 0.053 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase BsuPI PF12690.7 CDJ41812.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Intracellular proteinase inhibitor Methyltransf_24 PF13578.6 CDJ41812.1 - 0.065 14.3 0.0 0.13 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CDJ41812.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_2 PF00891.18 CDJ41812.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Ras PF00071.22 CDJ41813.1 - 5.3e-60 201.7 0.2 6.3e-60 201.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ41813.1 - 1.6e-34 118.7 0.1 2.6e-34 118.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ41813.1 - 8.8e-14 51.3 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ41813.1 - 6e-06 26.3 0.0 1.5e-05 25.0 0.0 1.6 1 1 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ41813.1 - 5.9e-05 22.5 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDJ41813.1 - 0.00029 20.8 0.2 0.11 12.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CDJ41813.1 - 0.00069 19.1 0.0 0.0014 18.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CDJ41813.1 - 0.0044 16.6 0.4 0.012 15.2 0.2 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CDJ41813.1 - 0.034 14.4 0.0 0.075 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ41813.1 - 0.036 14.4 0.3 0.073 13.5 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain SNF2_N PF00176.23 CDJ41813.1 - 0.085 11.6 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain DAP3 PF10236.9 CDJ41813.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Cu_amine_oxid PF01179.20 CDJ41814.1 - 2.1e-67 227.8 0.7 1.9e-66 224.7 0.7 2.2 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain MAM PF00629.23 CDJ41814.1 - 3.6e-30 105.0 0.0 7.1e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DUF1965 PF09248.10 CDJ41814.1 - 0.072 12.9 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Syntaxin-6_N PF09177.11 CDJ41816.1 - 0.64 10.6 8.0 1.5 9.5 0.2 3.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Phosphonate-bd PF12974.7 CDJ41818.1 - 0.05 13.2 0.1 0.13 11.9 0.1 1.6 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Brix PF04427.18 CDJ41820.1 - 8.6e-28 97.8 0.0 1.3e-27 97.2 0.0 1.3 1 0 0 1 1 1 1 Brix domain SAC3_GANP PF03399.16 CDJ41823.1 - 2.1e-07 30.6 7.1 6.5e-06 25.7 1.7 2.4 1 1 0 2 2 2 2 SAC3/GANP family DnaJ PF00226.31 CDJ41824.1 - 2e-13 50.2 0.2 4.2e-13 49.2 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain SNARE_assoc PF09335.11 CDJ41828.1 - 5.8e-08 33.2 6.3 0.00093 19.7 0.0 3.0 3 0 0 3 3 3 2 SNARE associated Golgi protein SelP_N PF04592.14 CDJ41828.1 - 0.16 11.4 4.5 0.23 10.8 4.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region EOS1 PF12326.8 CDJ41828.1 - 0.31 10.9 3.1 9.2 6.2 0.2 2.4 2 0 0 2 2 2 0 N-glycosylation protein DNA_topoisoIV PF00521.20 CDJ41830.1 - 5.3e-114 381.4 0.0 7.7e-114 380.9 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CDJ41830.1 - 1.2e-23 83.8 3.0 5.5e-17 62.2 0.1 3.1 2 1 1 3 3 3 2 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CDJ41830.1 - 3.5e-20 72.2 0.4 7.4e-20 71.1 0.4 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CDJ41830.1 - 1.6e-10 41.4 0.1 5.5e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CDJ41830.1 - 1.7e-07 31.4 0.0 4.5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Nucleoporin_FG PF13634.6 CDJ41831.1 - 2.1e-34 118.2 260.8 3.3e-10 40.7 38.8 9.4 2 2 7 9 9 9 9 Nucleoporin FG repeat region Ribosomal_S27 PF01599.19 CDJ41833.1 - 4.8e-26 90.7 2.8 9e-26 89.8 2.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 CDJ41833.1 - 1.1e-13 50.6 0.0 2.4e-13 49.6 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ41833.1 - 1.3e-05 24.9 0.0 4.5e-05 23.2 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CDJ41833.1 - 0.0067 16.5 0.3 0.027 14.5 0.0 2.1 3 1 0 3 3 3 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 CDJ41833.1 - 0.011 16.2 0.0 0.1 13.1 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 CDJ41833.1 - 0.034 14.4 0.9 0.056 13.7 0.9 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain EF_TS PF00889.19 CDJ41834.1 - 1.4e-21 77.1 0.0 5.1e-21 75.3 0.0 1.8 1 1 1 2 2 2 1 Elongation factor TS UBA PF00627.31 CDJ41834.1 - 0.0023 17.8 0.4 0.0071 16.2 0.4 1.9 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 CDJ41834.1 - 0.054 13.3 0.5 0.8 9.6 0.2 2.4 2 0 0 2 2 2 0 UBA-like domain SNase PF00565.17 CDJ41836.1 - 5.2e-11 43.0 0.0 0.014 15.8 0.0 4.5 4 0 0 4 4 4 3 Staphylococcal nuclease homologue TFIIA PF03153.13 CDJ41837.1 - 2.7 7.9 25.7 0.91 9.4 2.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Arf PF00025.21 CDJ41839.1 - 7.1e-30 103.7 0.0 8.9e-30 103.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CDJ41839.1 - 0.00026 20.6 0.0 0.00033 20.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CDJ41839.1 - 0.00027 20.4 0.0 0.0036 16.7 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CDJ41839.1 - 0.037 14.3 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Band_7 PF01145.25 CDJ41840.1 - 9.4e-30 103.9 0.0 1.7e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 CDJ41840.1 - 3.6e-16 58.9 1.6 3.6e-16 58.9 1.6 2.0 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 CDJ41840.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family 2OG-FeII_Oxy_3 PF13640.6 CDJ41841.1 - 2.4e-06 28.3 0.0 5.8e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GREB1 PF15782.5 CDJ41841.1 - 1 6.4 7.7 1.4 5.9 7.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Suf PF05843.14 CDJ41842.1 - 0.00067 19.7 27.2 0.062 13.3 5.1 2.2 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) AAA_11 PF13086.6 CDJ41842.1 - 0.0015 18.3 18.5 0.13 12.0 13.1 2.2 2 0 0 2 2 2 2 AAA domain Presenilin PF01080.17 CDJ41842.1 - 0.0026 16.6 21.5 0.016 14.0 1.7 2.2 2 0 0 2 2 2 2 Presenilin TFIIA PF03153.13 CDJ41842.1 - 0.0028 17.7 60.6 0.016 15.2 22.0 2.4 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit AIRS_C PF02769.22 CDJ41842.1 - 0.0053 16.9 0.1 0.018 15.2 0.1 2.0 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain RskA PF10099.9 CDJ41842.1 - 0.015 15.6 18.6 0.015 15.6 18.6 4.1 2 2 2 4 4 3 0 Anti-sigma-K factor rskA TCP PF03634.13 CDJ41842.1 - 0.023 15.3 22.7 0.091 13.3 0.5 2.8 2 1 0 2 2 2 0 TCP family transcription factor DUF3446 PF11928.8 CDJ41842.1 - 0.033 14.5 0.8 0.033 14.5 0.8 3.3 2 1 1 3 3 3 0 Early growth response N-terminal domain CDC45 PF02724.14 CDJ41842.1 - 0.056 11.7 17.0 0.43 8.8 0.1 2.3 2 0 0 2 2 2 0 CDC45-like protein Zip PF02535.22 CDJ41842.1 - 0.058 12.6 9.4 0.087 12.0 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 CDJ41842.1 - 0.13 12.3 17.4 0.32 11.0 1.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CAF1 PF04857.20 CDJ41842.1 - 0.24 10.5 9.1 1.7 7.7 3.8 2.1 2 0 0 2 2 2 0 CAF1 family ribonuclease DUF2052 PF09747.9 CDJ41842.1 - 0.26 11.4 26.4 0.32 11.1 0.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) GAGA_bind PF06217.12 CDJ41842.1 - 0.27 11.5 18.8 0.067 13.5 7.4 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family DUF3801 PF12687.7 CDJ41842.1 - 0.47 10.5 23.3 1.3 9.1 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) PAT1 PF09770.9 CDJ41842.1 - 0.54 8.5 36.5 0.055 11.8 8.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SID-1_RNA_chan PF13965.6 CDJ41842.1 - 0.76 8.1 7.0 4.2 5.7 2.5 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 CCSAP PF15748.5 CDJ41842.1 - 1.7 8.7 32.7 0.69 10.0 15.0 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated V_ATPase_I PF01496.19 CDJ41842.1 - 2.9 5.7 23.6 0.48 8.3 4.3 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family SR-25 PF10500.9 CDJ41842.1 - 4.4 6.9 29.1 0.17 11.4 2.6 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Tim54 PF11711.8 CDJ41842.1 - 6.1 5.5 20.5 0.7 8.6 3.9 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 XRN_M PF17846.1 CDJ41842.1 - 6.8 5.5 18.1 3.2 6.6 0.2 2.1 2 0 0 2 2 2 0 Xrn1 helical domain CLN3 PF02487.17 CDJ41842.1 - 7.2 5.5 15.1 2.3 7.1 1.6 2.2 2 0 0 2 2 2 0 CLN3 protein ADK PF00406.22 CDJ41843.1 - 1e-29 103.6 0.0 1.2e-22 80.6 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 CDJ41843.1 - 2.3e-24 86.3 0.0 2.7e-17 63.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CDJ41843.1 - 0.00061 20.3 0.0 0.49 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain SR-25 PF10500.9 CDJ41843.1 - 0.0019 17.8 2.8 0.0032 17.1 2.8 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Thymidylate_kin PF02223.17 CDJ41843.1 - 0.01 15.5 0.0 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.12 CDJ41843.1 - 0.081 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PmbA_TldD PF01523.16 CDJ41843.1 - 0.98 9.2 5.3 3.1 7.5 2.9 2.1 2 0 0 2 2 2 0 Putative modulator of DNA gyrase RskA PF10099.9 CDJ41843.1 - 1.6 9.0 26.2 0.032 14.5 2.2 3.0 3 0 0 3 3 3 0 Anti-sigma-K factor rskA DUF4692 PF15763.5 CDJ41843.1 - 2.2 8.8 5.4 2.3 8.7 4.2 1.6 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Shadoo PF14999.6 CDJ41843.1 - 3.3 7.8 25.7 2.3 8.3 5.0 3.0 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective RskA PF10099.9 CDJ41844.1 - 0.0086 16.4 5.7 0.013 15.8 5.7 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA IMUP PF15761.5 CDJ41844.1 - 0.052 14.2 15.0 0.06 14.0 15.0 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein CCDC106 PF15794.5 CDJ41844.1 - 1.5 8.4 17.9 1.8 8.2 17.9 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 FAM209 PF15206.6 CDJ41844.1 - 3.1 7.6 5.9 4.3 7.1 5.9 1.2 1 0 0 1 1 1 0 FAM209 family Spt20 PF12090.8 CDJ41845.1 - 0.38 10.3 11.5 0.17 11.5 8.9 1.7 2 0 0 2 2 2 0 Spt20 family CSN8_PSD8_EIF3K PF10075.9 CDJ41846.1 - 1.2e-06 28.6 0.1 1.2e-06 28.6 0.1 2.5 3 0 0 3 3 3 1 CSN8/PSMD8/EIF3K family DUF5134 PF17197.4 CDJ41846.1 - 0.0012 18.8 0.2 0.0018 18.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5134) LEDGF PF11467.8 CDJ41846.1 - 0.032 13.8 0.6 0.032 13.8 0.6 2.1 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) RskA PF10099.9 CDJ41846.1 - 2.7 8.2 12.4 0.39 11.0 8.1 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Thg1C PF14413.6 CDJ41847.1 - 1.5 9.0 8.0 0.5 10.5 1.5 2.3 2 0 0 2 2 2 0 Thg1 C terminal domain Spt20 PF12090.8 CDJ41847.1 - 3 7.4 43.5 0.041 13.5 17.7 2.2 2 0 0 2 2 2 0 Spt20 family TERB2 PF15101.6 CDJ41847.1 - 8.5 6.4 16.0 1.4 9.0 3.9 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 S4 PF01479.25 CDJ41848.1 - 2.2e-08 33.7 0.2 4.5e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 CDJ41848.1 - 1.1e-07 32.6 0.7 1.5e-07 32.2 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_S28e PF01200.18 CDJ41849.1 - 1.4e-31 108.3 1.5 1.5e-31 108.2 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Surface_antigen PF11054.8 CDJ41852.1 - 3.7e-15 56.3 9.0 4.6e-11 42.9 5.7 3.0 2 1 0 2 2 2 2 Sporozoite TA4 surface antigen PilI PF10623.9 CDJ41852.1 - 0.14 12.3 0.2 0.48 10.6 0.0 1.9 2 0 0 2 2 2 0 Plasmid conjugative transfer protein PilI PDE8 PF08629.10 CDJ41852.1 - 0.24 11.4 1.6 0.3 11.1 0.1 1.9 2 0 0 2 2 2 0 PDE8 phosphodiesterase Surface_antigen PF11054.8 CDJ41854.1 - 0.00023 20.9 0.1 0.00025 20.8 0.1 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Chorion_3 PF05387.11 CDJ41856.1 - 0.095 12.3 0.1 0.096 12.3 0.1 1.1 1 0 0 1 1 1 0 Chorion family 3 Surface_antigen PF11054.8 CDJ41857.1 - 8.6e-12 45.3 22.6 2.9e-10 40.2 6.0 5.5 5 2 1 6 6 6 3 Sporozoite TA4 surface antigen SPT2 PF08243.11 CDJ41858.1 - 1.4e-09 38.4 11.4 1.4e-09 38.4 11.4 6.0 6 2 0 6 6 6 1 SPT2 chromatin protein MCM PF00493.23 CDJ41859.1 - 4.6e-89 297.4 0.0 3.4e-80 268.3 0.0 2.2 1 1 1 2 2 2 2 MCM P-loop domain MCM_lid PF17855.1 CDJ41859.1 - 9.6e-20 70.8 0.0 2.3e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDJ41859.1 - 4.3e-10 39.3 0.3 9.2e-07 28.4 0.1 3.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CDJ41859.1 - 4.8e-06 26.4 0.0 4.3e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 CDJ41859.1 - 2.5e-05 24.3 0.0 0.00012 22.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDJ41859.1 - 0.001 19.0 0.0 0.0051 16.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 CDJ41859.1 - 0.023 15.1 0.1 0.1 13.0 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ41859.1 - 0.16 11.7 0.2 2.2 8.0 0.2 2.5 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDJ41859.1 - 0.24 11.6 4.4 9.7 6.5 0.0 3.5 4 0 0 4 4 4 0 AAA domain Ribosomal_60s PF00428.19 CDJ41859.1 - 0.34 11.5 15.7 0.045 14.3 9.1 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein AAA_16 PF13191.6 CDJ41859.1 - 0.46 10.9 0.0 0.46 10.9 0.0 3.7 3 1 1 4 4 4 0 AAA ATPase domain RskA PF10099.9 CDJ41859.1 - 2 8.6 17.4 2.9 8.1 5.8 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DHHC PF01529.20 CDJ41860.1 - 2.7e-21 76.1 11.8 2.7e-21 76.1 11.8 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase MCM_N PF14551.6 CDJ41860.1 - 3.5e-10 40.4 0.1 6.1e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.8 CDJ41860.1 - 0.025 14.9 8.3 0.025 14.9 8.3 1.8 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 XK-related PF09815.9 CDJ41860.1 - 0.048 12.7 0.3 0.098 11.7 0.0 1.6 2 0 0 2 2 2 0 XK-related protein RskA PF10099.9 CDJ41860.1 - 8.2 6.7 23.2 4.7 7.5 4.1 2.5 1 1 0 2 2 2 0 Anti-sigma-K factor rskA Radical_SAM PF04055.21 CDJ41861.1 - 3e-06 27.7 0.0 0.017 15.5 0.0 2.3 2 0 0 2 2 2 2 Radical SAM superfamily HemN_C PF06969.16 CDJ41861.1 - 0.00073 19.5 0.3 0.0063 16.6 0.3 2.7 1 0 0 1 1 1 1 HemN C-terminal domain ESM4 PF15952.5 CDJ41861.1 - 1.3 9.4 45.5 0.89 10.0 5.6 4.3 4 0 0 4 4 4 0 Enhancer of split M4 family DUF1786 PF08735.10 CDJ41862.1 - 0.17 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) DUF456 PF04306.13 CDJ41864.1 - 0.022 15.1 4.9 0.041 14.2 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Romo1 PF10247.9 CDJ41864.1 - 0.081 13.3 3.9 0.34 11.3 3.9 2.1 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF1269 PF06897.12 CDJ41864.1 - 0.088 13.1 5.1 0.26 11.6 5.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Hep_59 PF07052.11 CDJ41865.1 - 8.7e-21 74.7 2.0 8.7e-21 74.7 2.0 2.1 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Nbs1_C PF08599.10 CDJ41865.1 - 3.6 7.8 5.4 2.8 8.2 1.2 2.6 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 Aminotran_1_2 PF00155.21 CDJ41867.1 - 1.1e-39 136.7 0.0 3.3e-39 135.1 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II DAO PF01266.24 CDJ41868.1 - 6.6e-38 131.2 0.0 1.1e-37 130.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CDJ41868.1 - 2.1e-29 102.0 0.0 4e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_oxidored PF12831.7 CDJ41868.1 - 9.4e-05 21.9 1.0 0.01 15.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CDJ41868.1 - 0.00034 20.0 0.1 0.013 14.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 CDJ41868.1 - 0.015 14.4 2.2 0.045 12.8 0.4 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 CDJ41868.1 - 0.035 13.3 0.1 0.19 10.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ABC_tran PF00005.27 CDJ41869.1 - 4.6e-19 69.3 0.3 2e-18 67.2 0.0 2.3 3 0 0 3 3 2 1 ABC transporter ABC_membrane PF00664.23 CDJ41869.1 - 3.1e-15 56.5 0.7 3.1e-15 56.5 0.7 2.3 3 0 0 3 3 2 1 ABC transporter transmembrane region SbcCD_C PF13558.6 CDJ41869.1 - 3.3e-05 24.0 0.0 0.00012 22.2 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 CDJ41869.1 - 0.00042 20.7 0.2 0.00042 20.7 0.2 2.5 3 0 0 3 3 2 1 AAA ATPase domain SMC_N PF02463.19 CDJ41869.1 - 0.0011 18.4 2.5 0.1 12.0 0.0 2.6 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ41869.1 - 0.019 14.7 0.1 0.061 13.1 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CDJ41869.1 - 0.054 13.1 0.2 0.3 10.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain FAM176 PF14851.6 CDJ41869.1 - 0.058 13.0 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 FAM176 family AAA_18 PF13238.6 CDJ41869.1 - 0.079 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDJ41869.1 - 0.11 12.8 0.0 0.11 12.8 0.0 3.1 3 1 0 3 3 3 0 AAA domain Roughex PF06020.11 CDJ41869.1 - 1.9 7.5 5.2 3.6 6.6 5.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Patatin PF01734.22 CDJ41871.1 - 0.12 12.5 2.8 0.37 10.9 2.8 1.9 1 1 0 1 1 1 0 Patatin-like phospholipase Glutaredoxin PF00462.24 CDJ41873.1 - 5.6e-12 45.7 0.0 9.8e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin LRR_9 PF14580.6 CDJ41874.1 - 7.2e-10 38.6 0.1 1.9e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CDJ41874.1 - 8.7e-05 22.8 2.0 0.28 11.6 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ41874.1 - 0.86 9.4 9.0 17 5.2 4.9 2.6 1 1 1 3 3 3 0 Leucine rich repeat GpcrRhopsn4 PF10192.9 CDJ41875.1 - 4.8e-09 36.0 0.2 4.8e-09 36.0 0.2 1.6 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Exo_endo_phos PF03372.23 CDJ41875.1 - 4.5e-07 29.6 0.0 4.5e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family TFIIA PF03153.13 CDJ41875.1 - 0.027 14.5 59.5 0.35 10.8 48.7 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ni_hydr_CYTB PF01292.20 CDJ41875.1 - 0.77 9.3 5.7 2.8 7.5 3.6 2.7 1 1 2 3 3 3 0 Prokaryotic cytochrome b561 SGS PF05002.15 CDJ41876.1 - 7.9e-30 102.8 0.8 1.9e-29 101.6 0.8 1.6 1 0 0 1 1 1 1 SGS domain CS PF04969.16 CDJ41876.1 - 2.5e-13 50.8 0.4 4.9e-13 49.9 0.4 1.5 1 0 0 1 1 1 1 CS domain Trypan_glycop PF00913.19 CDJ41876.1 - 0.14 11.4 1.4 0.95 8.7 1.4 1.9 1 1 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Ribosomal_L3 PF00297.22 CDJ41878.1 - 1.8e-172 573.4 2.6 2.1e-172 573.2 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 RNA_pol_Rpb2_3 PF04565.16 CDJ41881.1 - 7.7e-27 93.3 0.0 1.9e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.15 CDJ41881.1 - 1e-26 93.7 0.0 1.6e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CDJ41881.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.7 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_6 PF00562.28 CDJ41882.1 - 1.4e-116 389.8 0.0 2e-116 389.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 CDJ41882.1 - 1.1e-13 51.3 0.0 2.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Rad50_zn_hook PF04423.14 CDJ41882.1 - 0.11 12.3 0.3 0.21 11.4 0.3 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif Lactamase_B_2 PF12706.7 CDJ41884.1 - 2e-06 27.5 3.6 0.0003 20.4 0.3 3.7 2 2 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ41884.1 - 0.0003 20.9 0.1 0.0024 17.9 0.1 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RRM_1 PF00076.22 CDJ41885.1 - 1.3e-07 31.4 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ41885.1 - 0.045 13.6 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Se-cys_synth_N PF12390.8 CDJ41887.1 - 0.47 10.7 3.4 11 6.3 3.4 3.6 1 0 0 1 1 1 0 Selenocysteine synthase N terminal Peptidase_C26 PF07722.13 CDJ41888.1 - 7.1e-17 61.9 0.0 3.6e-12 46.5 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 GATase PF00117.28 CDJ41888.1 - 3.3e-12 46.6 0.1 3.6e-11 43.2 0.1 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I AMP-binding PF00501.28 CDJ41889.1 - 1.2e-77 261.3 0.0 1.9e-77 260.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ41889.1 - 0.0005 21.0 0.0 0.0011 19.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IFR3_antag PF14754.6 CDJ41890.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Papain-like auto-proteinase TFIIA PF03153.13 CDJ41890.1 - 6.6 6.6 53.4 2.5 8.0 26.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Bul1_N PF04425.12 CDJ41891.1 - 5.5 5.6 18.3 6.6 5.4 18.3 1.0 1 0 0 1 1 1 0 Bul1 N terminus DEAD PF00270.29 CDJ41892.1 - 8.8e-44 149.4 0.0 2.4e-43 148.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ41892.1 - 5.1e-33 113.7 0.0 3e-32 111.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ41892.1 - 5.2e-05 23.3 0.0 0.00016 21.7 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDJ41892.1 - 0.00057 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ41892.1 - 0.01 16.2 0.0 0.027 14.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 CDJ41892.1 - 0.028 13.6 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CDJ41892.1 - 0.029 13.7 0.0 0.21 10.9 0.0 2.1 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF72 PF01904.18 CDJ41892.1 - 0.067 13.3 0.1 0.098 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF72 BAF1_ABF1 PF04684.13 CDJ41893.1 - 3.6 6.5 35.0 4.6 6.2 35.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PTS_2-RNA PF01885.16 CDJ41894.1 - 5.1e-42 144.0 0.0 7.4e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family HAT PF02184.16 CDJ41896.1 - 0.025 14.5 0.0 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat DUF1800 PF08811.11 CDJ41896.1 - 0.17 10.9 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Cullin_Nedd8 PF10557.9 CDJ41897.1 - 2.7e-13 49.7 0.1 4.8e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.22 CDJ41897.1 - 5.2e-11 41.9 0.0 6.4e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Cullin family DUF1645 PF07816.11 CDJ41898.1 - 0.00028 21.5 16.8 0.0027 18.3 0.5 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1645) Utp14 PF04615.13 CDJ41898.1 - 0.016 13.8 6.4 0.02 13.5 6.4 1.1 1 0 0 1 1 1 0 Utp14 protein MID_MedPIWI PF18296.1 CDJ41898.1 - 0.21 11.4 10.3 0.043 13.6 4.3 2.2 2 0 0 2 2 2 0 MID domain of medPIWI PI3K_1B_p101 PF10486.9 CDJ41898.1 - 0.58 7.9 9.3 1 7.1 9.3 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit AF-4 PF05110.13 CDJ41898.1 - 0.81 7.7 35.0 0.015 13.4 18.8 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Plasmodium_Vir PF05795.11 CDJ41898.1 - 8.3 5.7 7.2 19 4.5 1.7 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Ribosomal_S8 PF00410.19 CDJ41899.1 - 1.1e-14 54.5 0.0 2.2e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S8 GREB1 PF15782.5 CDJ41899.1 - 0.13 9.3 31.9 0.16 9.0 31.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Utp14 PF04615.13 CDJ41899.1 - 0.29 9.7 16.5 0.37 9.3 16.5 1.1 1 0 0 1 1 1 0 Utp14 protein BPL_N PF09825.9 CDJ41899.1 - 2 7.4 8.6 2.7 7.0 8.6 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal SWI-SNF_Ssr4 PF08549.10 CDJ41899.1 - 2.2 6.8 25.5 3 6.4 25.5 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PAT1 PF09770.9 CDJ41899.1 - 2.7 6.2 30.1 4.5 5.4 30.2 1.3 1 1 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PSS PF03034.15 CDJ41900.1 - 0.0011 18.8 1.8 0.0029 17.4 0.1 2.0 1 1 1 2 2 2 1 Phosphatidyl serine synthase Aminotran_1_2 PF00155.21 CDJ41900.1 - 0.02 14.1 6.5 0.066 12.4 6.5 1.9 1 1 0 1 1 1 0 Aminotransferase class I and II Peptidase_S15 PF02129.18 CDJ41900.1 - 0.034 13.7 8.5 0.073 12.7 8.5 1.6 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ndc1_Nup PF09531.10 CDJ41900.1 - 0.055 12.2 11.2 0.067 11.9 11.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 CDJ41900.1 - 0.071 11.8 9.5 0.086 11.5 9.5 1.0 1 0 0 1 1 1 0 Hamartin protein eIF-3_zeta PF05091.12 CDJ41900.1 - 0.12 11.3 10.1 0.15 11.0 10.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FliP PF00813.20 CDJ41900.1 - 0.45 10.4 2.0 0.72 9.7 2.0 1.4 1 0 0 1 1 1 0 FliP family LMBR1 PF04791.16 CDJ41900.1 - 0.49 9.2 4.2 0.67 8.8 4.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 CDJ41900.1 - 1.2 7.8 10.5 1.6 7.4 10.5 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CDJ41900.1 - 1.3 7.1 11.5 1.6 6.8 11.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCSAP PF15748.5 CDJ41900.1 - 1.4 9.1 18.1 2 8.5 18.1 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated VIR_N PF15912.5 CDJ41900.1 - 2.1 7.9 8.8 3.5 7.1 8.8 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal FAM60A PF15396.6 CDJ41900.1 - 3.5 7.6 7.5 5.3 7.0 7.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A PA26 PF04636.13 CDJ41900.1 - 4 6.3 9.5 5.1 5.9 9.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Alph_Pro_TM PF09608.10 CDJ41900.1 - 4.3 7.1 7.2 6.3 6.5 7.2 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) GET2 PF08690.10 CDJ41900.1 - 5.6 6.5 15.0 9 5.9 15.0 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Sin_N PF04801.13 CDJ41900.1 - 6.3 5.9 20.9 8.7 5.4 20.9 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF737 PF05300.11 CDJ41900.1 - 6.6 7.0 19.8 10 6.4 19.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) AAA_32 PF13654.6 CDJ41900.1 - 6.6 5.4 12.3 8.4 5.0 12.3 1.1 1 0 0 1 1 1 0 AAA domain Suf PF05843.14 CDJ41900.1 - 9.6 6.1 16.0 17 5.3 16.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PepSY_2 PF13670.6 CDJ41901.1 - 0.63 10.1 4.6 8.1 6.5 0.1 2.5 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Collagen PF01391.18 CDJ41901.1 - 6.8 6.5 34.3 0.037 13.8 13.1 2.5 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Abhydrolase_1 PF00561.20 CDJ41903.1 - 5.1e-12 46.0 0.1 1.7e-10 41.0 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ41903.1 - 9.7e-11 42.7 4.0 9.7e-11 42.7 4.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ41903.1 - 9.2e-09 34.9 0.7 4.4e-08 32.7 0.1 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CDJ41903.1 - 0.0041 16.9 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 CDJ41903.1 - 0.015 15.4 0.1 0.044 13.9 0.1 1.8 1 0 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.12 CDJ41903.1 - 0.037 14.0 0.0 0.58 10.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) LIDHydrolase PF10230.9 CDJ41903.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Pex14_N PF04695.13 CDJ41904.1 - 3.6e-05 24.5 4.2 3.6e-05 24.5 4.2 1.7 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Pyrid_ox_like PF16242.5 CDJ41904.1 - 0.0045 16.6 0.0 0.0075 15.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like AP2 PF00847.20 CDJ41905.1 - 2.5e-07 30.8 1.4 1.6e-05 25.0 0.3 3.2 2 0 0 2 2 2 1 AP2 domain RskA PF10099.9 CDJ41905.1 - 0.00047 20.5 0.9 0.00047 20.5 0.9 16.7 3 3 7 10 10 10 1 Anti-sigma-K factor rskA Carb_kinase PF01256.17 CDJ41907.1 - 6.9e-30 104.3 0.1 1.7e-18 67.0 0.0 3.7 3 1 0 3 3 3 3 Carbohydrate kinase Spt20 PF12090.8 CDJ41907.1 - 0.36 10.4 7.3 0.6 9.7 7.3 1.3 1 0 0 1 1 1 0 Spt20 family Neur_chan_memb PF02932.16 CDJ41907.1 - 5 7.1 5.7 6.7 6.7 5.7 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Proteasome PF00227.26 CDJ41908.1 - 6.9e-56 188.7 0.0 8.5e-56 188.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ41908.1 - 1.2e-13 50.5 0.0 2.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 CDJ41908.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Chromo PF00385.24 CDJ41909.1 - 0.0042 17.0 0.0 0.0089 15.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 CDJ41910.1 - 8.6e-20 70.6 0.0 1.4e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ41910.1 - 5.1e-14 52.4 0.0 8.5e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ41910.1 - 0.0016 18.0 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ldl_recept_b PF00058.17 CDJ41910.1 - 0.15 12.6 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 Low-density lipoprotein receptor repeat class B Pkinase PF00069.25 CDJ41912.1 - 5.2e-44 150.6 1.4 8.6e-21 74.5 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ41912.1 - 5.9e-18 65.1 0.0 3.2e-10 39.7 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase PseudoU_synth_1 PF01416.20 CDJ41914.1 - 1.8e-19 70.2 0.1 8.9e-17 61.5 0.0 3.3 3 0 0 3 3 3 1 tRNA pseudouridine synthase Prot_ATP_ID_OB PF16450.5 CDJ41914.1 - 0.081 12.9 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain TFIIA PF03153.13 CDJ41917.1 - 0.0013 18.8 9.8 0.0023 18.0 9.8 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ41919.1 - 0.38 10.3 20.5 0.17 11.5 9.7 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ41919.1 - 6.1 6.7 32.2 0.42 10.5 10.1 2.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ41919.1 - 9.3 5.7 9.2 26 4.2 9.2 1.7 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MMR_HSR1 PF01926.23 CDJ41920.1 - 4.2e-11 42.9 0.1 1e-10 41.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ41920.1 - 6.7e-10 39.1 0.0 1.4e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 CDJ41920.1 - 5.9e-06 25.9 2.0 0.31 10.6 0.1 3.2 2 1 1 3 3 3 3 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 CDJ41920.1 - 0.0014 18.6 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Arf PF00025.21 CDJ41920.1 - 0.006 16.1 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.22 CDJ41920.1 - 0.012 15.2 0.0 0.094 12.3 0.0 2.0 2 0 0 2 2 2 0 Ras family Toprim_3 PF13362.6 CDJ41920.1 - 0.026 14.9 0.0 0.047 14.0 0.0 1.3 1 0 0 1 1 1 0 Toprim domain AAA_29 PF13555.6 CDJ41920.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 CDJ41920.1 - 0.4 10.2 1.3 0.43 10.2 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain LRR_4 PF12799.7 CDJ41921.1 - 0.028 14.8 3.7 29 5.3 0.0 5.2 5 1 0 6 6 6 0 Leucine Rich repeats (2 copies) Peptidase_C97 PF05903.14 CDJ41923.1 - 1.1e-24 87.0 0.0 2.7e-23 82.5 0.0 2.2 1 1 0 1 1 1 1 PPPDE putative peptidase domain PepSY_TM PF03929.16 CDJ41923.1 - 0.43 10.2 3.2 0.31 10.7 0.6 1.9 2 0 0 2 2 2 0 PepSY-associated TM region EccE PF11203.8 CDJ41923.1 - 0.44 10.9 11.2 0.022 15.1 4.2 2.5 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE TPR_12 PF13424.6 CDJ41924.1 - 0.003 17.8 7.8 0.67 10.3 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ41924.1 - 0.0073 16.1 2.5 3.4 7.7 0.5 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ41924.1 - 0.019 15.1 7.2 11 6.5 1.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CDJ41924.1 - 0.097 12.7 0.0 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 Putative TPR-like repeat TPR_10 PF13374.6 CDJ41924.1 - 0.64 10.0 5.0 20 5.2 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CDJ41924.1 - 3 8.3 5.6 6.4 7.2 0.0 3.1 3 1 0 4 4 4 0 Alkyl sulfatase dimerisation TPR_9 PF13371.6 CDJ41924.1 - 4.9 7.4 8.4 6.9 6.9 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat EPL1 PF10513.9 CDJ41925.1 - 4e-05 24.1 2.3 7.5e-05 23.2 0.1 2.6 2 1 0 2 2 2 1 Enhancer of polycomb-like TipAS PF07739.13 CDJ41925.1 - 0.037 14.6 3.7 0.14 12.7 3.7 2.0 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain 5-FTHF_cyc-lig PF01812.20 CDJ41926.1 - 1.3e-14 54.5 0.0 5.4e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family Pkinase PF00069.25 CDJ41927.1 - 9.4e-27 94.0 0.0 5.8e-26 91.4 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ41927.1 - 4.1e-12 46.0 0.0 3.8e-11 42.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase LAP1C PF05609.12 CDJ41927.1 - 1.1 8.2 17.2 2 7.4 17.2 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BT1 PF03092.16 CDJ41928.1 - 1.3e-75 254.6 16.1 5.8e-73 245.9 16.1 2.1 1 1 0 1 1 1 1 BT1 family PAP1 PF08601.10 CDJ41928.1 - 7.6 6.2 9.3 12 5.5 9.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 SID-1_RNA_chan PF13965.6 CDJ41932.1 - 7.8 4.8 7.0 19 3.5 7.0 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3682 PF12446.8 CDJ41933.1 - 0.044 14.3 19.5 0.058 13.9 19.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) TPPII_N PF12583.8 CDJ41933.1 - 6.1 7.4 17.2 7.9 7.1 17.2 1.1 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal DUF2567 PF10821.8 CDJ41934.1 - 0.024 14.7 5.2 0.28 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) CDC45 PF02724.14 CDJ41934.1 - 0.075 11.3 10.6 0.089 11.1 10.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ41934.1 - 2.5 6.8 27.0 3.9 6.1 27.0 1.2 1 0 0 1 1 1 0 Presenilin LcrG PF07216.12 CDJ41935.1 - 0.0061 16.5 2.5 0.0061 16.5 1.3 1.7 1 1 0 1 1 1 1 LcrG protein DUF1839 PF08893.10 CDJ41935.1 - 0.013 14.7 2.2 0.016 14.4 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) DUF334 PF03904.13 CDJ41935.1 - 0.06 12.9 0.6 0.084 12.4 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF790 PF05626.11 CDJ41935.1 - 0.061 12.0 4.4 0.083 11.6 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF790) Yuri_gagarin PF15934.5 CDJ41935.1 - 0.12 12.2 2.9 0.2 11.5 2.9 1.3 1 1 0 1 1 1 0 Yuri gagarin MCU PF04678.13 CDJ41935.1 - 0.42 10.7 2.7 0.68 10.0 2.7 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter RskA PF10099.9 CDJ41935.1 - 2 8.7 19.7 0.5 10.6 4.9 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF4140 PF13600.6 CDJ41935.1 - 3.7 8.1 11.5 26 5.3 11.5 2.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SR-25 PF10500.9 CDJ41936.1 - 4.8 6.7 9.8 5.8 6.5 9.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ41937.1 - 0.7 8.7 29.3 0.29 10.0 21.7 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain SOBP PF15279.6 CDJ41937.1 - 4 8.0 25.5 8.2 6.9 6.8 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein DUF846 PF05832.12 CDJ41938.1 - 1.8e-19 70.1 5.8 2.1e-19 69.9 5.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Ribosomal_L18p PF00861.22 CDJ41939.1 - 1.1e-20 74.1 15.7 7.3e-15 55.4 3.8 2.6 3 0 0 3 3 3 2 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast RskA PF10099.9 CDJ41940.1 - 0.0052 17.1 9.7 0.0052 17.1 9.7 3.7 2 1 1 3 3 3 1 Anti-sigma-K factor rskA EMC3_TMCO1 PF01956.16 CDJ41940.1 - 0.79 9.4 2.1 1.6 8.5 2.1 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like eIF2A PF08662.11 CDJ41941.1 - 2.8e-24 86.1 1.5 2.8e-24 86.1 1.5 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DDE_Tnp_ISL3 PF01610.17 CDJ41941.1 - 3.6 7.2 8.3 5.8 6.6 8.3 1.2 1 0 0 1 1 1 0 Transposase Ephrin_rec_like PF07699.13 CDJ41942.1 - 8.4e-10 38.3 11.4 0.00011 21.9 2.8 2.7 2 1 0 2 2 2 2 Putative ephrin-receptor like Dirigent PF03018.14 CDJ41942.1 - 0.074 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Dirigent-like protein PsbQ PF05757.11 CDJ41942.1 - 3.7 7.2 7.2 11 5.7 7.2 1.8 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) PAP_central PF04928.17 CDJ41944.1 - 3.3e-83 278.5 0.0 8.2e-83 277.2 0.0 1.6 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CDJ41944.1 - 3.3e-13 49.6 0.0 1.5e-08 34.5 0.4 2.7 2 0 0 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CDJ41944.1 - 7.7e-09 35.7 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 CDJ41944.1 - 0.00015 21.6 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain CH_2 PF06294.11 CDJ41945.1 - 3.3e-17 62.4 0.0 9.2e-17 61.0 0.0 1.8 1 0 0 1 1 1 1 CH-like domain in sperm protein ADK PF00406.22 CDJ41945.1 - 0.12 12.5 0.0 18 5.4 0.0 2.8 2 0 0 2 2 2 0 Adenylate kinase SpoU_methylase PF00588.19 CDJ41947.1 - 1.9e-08 34.5 0.0 7.1e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 SpoU rRNA Methylase family RRM_1 PF00076.22 CDJ41949.1 - 4e-18 65.0 0.1 7.3e-18 64.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP_SPB PF02978.19 CDJ41949.1 - 0.0024 18.5 0.8 0.0066 17.0 0.8 1.7 1 0 0 1 1 1 1 Signal peptide binding domain TFIIA PF03153.13 CDJ41949.1 - 0.058 13.4 8.9 0.051 13.6 7.5 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Chromo PF00385.24 CDJ41950.1 - 1.5e-09 37.6 0.3 2.8e-09 36.8 0.3 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TAF4 PF05236.14 CDJ41950.1 - 1.2 8.8 21.5 0.3 10.8 0.5 3.6 3 1 0 3 3 3 0 Transcription initiation factor TFIID component TAF4 family AAR2 PF05282.11 CDJ41951.1 - 4.5e-53 180.9 0.0 4.1e-52 177.7 0.0 2.0 2 0 0 2 2 2 1 AAR2 protein OHA PF14418.6 CDJ41952.1 - 4.9e-15 55.1 0.0 2e-14 53.1 0.0 2.1 1 0 0 1 1 1 1 OST-HTH Associated domain OST-HTH PF12872.7 CDJ41952.1 - 0.0028 17.4 0.0 0.0072 16.1 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Utp14 PF04615.13 CDJ41952.1 - 6.2 5.3 42.7 9.2 4.7 42.7 1.1 1 0 0 1 1 1 0 Utp14 protein AOX PF01786.17 CDJ41953.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Alternative oxidase K_channel_TID PF07941.11 CDJ41953.1 - 1.2 9.6 7.0 0.14 12.6 2.2 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF4317 PF14199.6 CDJ41954.1 - 0.027 13.6 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) TFIIA PF03153.13 CDJ41954.1 - 0.066 13.2 8.6 0.07 13.1 8.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 CDJ41955.1 - 4.5e-05 23.0 0.0 4.5e-05 23.0 0.0 3.6 5 0 0 5 5 5 1 Protein kinase domain Cyclin_N PF00134.23 CDJ41955.1 - 0.0037 17.0 2.5 0.0037 17.0 2.5 3.7 5 0 0 5 5 5 1 Cyclin, N-terminal domain SR-25 PF10500.9 CDJ41956.1 - 0.01 15.5 7.1 0.01 15.5 7.1 6.0 4 1 2 6 6 6 0 Nuclear RNA-splicing-associated protein Porin_3 PF01459.22 CDJ41957.1 - 5.8e-18 65.3 0.1 7.2e-18 65.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin NAD_binding_1 PF00175.21 CDJ41958.1 - 2.8e-14 53.7 1.4 6.1e-12 46.1 0.2 2.6 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 CDJ41958.1 - 8.9e-12 45.1 0.2 3.9e-11 42.9 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain NAD_binding_6 PF08030.12 CDJ41958.1 - 0.0003 20.9 0.1 0.015 15.4 0.0 2.9 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Chlorophyllase PF07224.11 CDJ41958.1 - 0.027 13.5 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase EntA_Immun PF08951.10 CDJ41958.1 - 0.11 12.9 1.1 0.2 12.0 1.1 1.4 1 0 0 1 1 1 0 Enterocin A Immunity RNA_pol_Rpb1_3 PF04983.18 CDJ41958.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 TFIIA PF03153.13 CDJ41958.1 - 0.63 10.0 10.4 2.8 7.9 1.4 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Tymo_45kd_70kd PF03251.13 CDJ41959.1 - 0.024 13.6 13.3 0.052 12.5 6.8 2.2 1 1 0 2 2 2 0 Tymovirus 45/70Kd protein Spc24 PF08286.11 CDJ41959.1 - 0.35 11.1 9.8 0.2 11.9 7.6 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF572 PF04502.13 CDJ41959.1 - 0.9 9.1 15.1 1.2 8.7 15.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Glyco_hydro_35 PF01301.19 CDJ41959.1 - 2.4 7.7 10.1 4 7.0 10.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 DUF4698 PF15769.5 CDJ41959.1 - 2.7 7.0 18.7 5.2 6.0 18.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Lambda_Bor PF06291.11 CDJ41959.1 - 6.1 7.0 10.6 6.4 6.9 0.1 3.3 3 0 0 3 3 3 0 Bor protein DUF789 PF05623.12 CDJ41960.1 - 2.9e-36 125.7 6.6 4.3e-35 121.8 6.6 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF789) SR-25 PF10500.9 CDJ41960.1 - 0.01 15.4 9.5 0.01 15.4 9.5 5.4 4 1 0 4 4 4 0 Nuclear RNA-splicing-associated protein Suf PF05843.14 CDJ41960.1 - 3.2 7.7 9.1 0.29 11.1 4.0 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4551 PF15087.6 CDJ41960.1 - 4.5 6.0 5.9 11 4.8 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pkinase PF00069.25 CDJ41961.1 - 8.7e-67 225.3 0.0 1.2e-66 224.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ41961.1 - 3e-39 134.9 0.0 5e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ41961.1 - 2.9e-33 110.9 3.9 1.7e-06 27.2 0.0 6.6 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 CDJ41961.1 - 4.4e-33 113.6 0.7 1.6e-11 44.5 0.0 4.7 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ41961.1 - 5.8e-29 97.5 4.3 4.6e-05 23.0 0.0 6.6 6 0 0 6 6 6 5 EF-hand domain EF-hand_5 PF13202.6 CDJ41961.1 - 6.3e-27 91.9 8.8 3.7e-07 29.3 0.0 6.7 7 0 0 7 7 7 4 EF hand EF-hand_8 PF13833.6 CDJ41961.1 - 1.1e-20 73.2 5.7 3e-05 23.8 0.0 5.7 3 3 3 6 6 6 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ41961.1 - 2.9e-07 30.8 0.8 0.0076 16.6 0.0 2.9 3 0 0 3 3 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDJ41961.1 - 1e-06 28.6 1.3 0.056 13.4 0.0 3.4 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 CDJ41961.1 - 1.6e-06 27.6 0.0 3.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDJ41961.1 - 1.3e-05 24.7 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like EF-hand_9 PF14658.6 CDJ41961.1 - 0.00028 21.1 0.0 0.95 9.8 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain APH PF01636.23 CDJ41961.1 - 0.0045 16.9 0.0 0.23 11.3 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_10 PF14788.6 CDJ41961.1 - 0.01 15.7 0.1 24 4.9 0.0 4.5 4 1 1 5 5 5 0 EF hand Choline_kinase PF01633.20 CDJ41961.1 - 0.06 12.9 0.2 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Dockerin_1 PF00404.18 CDJ41961.1 - 0.071 13.3 0.5 2.8e+02 1.8 0.0 4.6 4 1 0 4 4 4 0 Dockerin type I domain PDH PF02153.17 CDJ41961.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase DUF892 PF05974.12 CDJ41961.1 - 0.15 12.1 0.1 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF892) DUF3675 PF12428.8 CDJ41963.1 - 0.00049 20.6 0.3 0.00089 19.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3675) Phage_GPO PF05929.11 CDJ41963.1 - 0.003 17.2 10.0 0.0049 16.5 10.0 1.2 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase DUF812 PF05667.11 CDJ41963.1 - 0.0032 16.4 2.1 0.0038 16.2 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Synaptobrevin PF00957.21 CDJ41963.1 - 0.023 14.5 0.4 0.038 13.8 0.4 1.3 1 0 0 1 1 1 0 Synaptobrevin DUF4407 PF14362.6 CDJ41963.1 - 0.025 14.0 6.4 0.023 14.1 5.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TACC_C PF05010.14 CDJ41963.1 - 0.15 11.8 9.3 0.25 11.1 9.3 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Sipho_Gp157 PF05565.11 CDJ41963.1 - 0.18 11.8 6.9 0.28 11.2 6.9 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 SNARE PF05739.19 CDJ41963.1 - 0.42 10.6 4.7 1.6 8.8 4.7 2.0 1 1 0 1 1 1 0 SNARE domain DUF1664 PF07889.12 CDJ41963.1 - 0.65 10.0 6.2 1.1 9.3 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MCU PF04678.13 CDJ41963.1 - 0.65 10.1 6.7 0.17 11.9 3.5 1.6 2 0 0 2 2 2 0 Mitochondrial calcium uniporter THOC7 PF05615.13 CDJ41963.1 - 3.1 8.1 9.5 4.9 7.4 9.5 1.4 1 1 0 1 1 1 0 Tho complex subunit 7 DUF4199 PF13858.6 CDJ41963.1 - 3.3 8.1 6.3 0.45 10.9 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Seryl_tRNA_N PF02403.22 CDJ41963.1 - 5.9 7.2 12.5 10 6.4 10.5 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain U3_assoc_6 PF08640.11 CDJ41964.1 - 2.1e-10 40.5 3.2 2.1e-10 40.5 3.2 2.5 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 CDJ41964.1 - 0.00021 21.9 3.8 0.00021 21.9 3.8 9.9 8 2 1 9 9 9 1 Tetratricopeptide repeat RskA PF10099.9 CDJ41965.1 - 0.022 15.0 3.5 0.034 14.5 3.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF1003 PF06210.11 CDJ41965.1 - 4.9 7.3 7.0 1.5 9.0 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) F-box-like PF12937.7 CDJ41966.1 - 0.0027 17.6 2.8 0.0027 17.6 2.8 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDJ41966.1 - 0.36 10.8 3.1 0.76 9.7 3.1 1.5 1 0 0 1 1 1 0 F-box domain V_ATPase_I PF01496.19 CDJ41966.1 - 5.1 4.9 14.1 7.2 4.4 14.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 CDJ41966.1 - 5.1 6.8 12.9 4.4 7.1 10.5 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 AAA PF00004.29 CDJ41967.1 - 2.6e-15 57.0 0.4 2.8e-14 53.7 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CDJ41967.1 - 0.0098 16.1 7.3 0.092 12.9 0.0 4.5 5 1 0 5 5 5 1 AAA domain Dehydrin PF00257.19 CDJ41967.1 - 0.013 16.0 2.3 0.013 16.0 2.3 9.4 8 1 0 9 9 9 0 Dehydrin AAA_17 PF13207.6 CDJ41967.1 - 0.051 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain EB1 PF03271.17 CDJ41968.1 - 8e-13 48.4 0.0 1.8e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 CDJ41968.1 - 0.00044 20.4 0.8 0.00068 19.8 0.8 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain TFIIA PF03153.13 CDJ41968.1 - 0.092 12.7 7.8 0.11 12.4 7.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit STIMATE PF12400.8 CDJ41969.1 - 4.2e-06 27.3 0.0 6.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 STIMATE family ASFV_J13L PF05568.11 CDJ41969.1 - 1.2 8.8 7.5 2 8.2 7.5 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Surface_antigen PF11054.8 CDJ41970.1 - 4.2e-32 111.8 9.4 6.2e-31 107.9 9.3 2.0 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ41971.1 - 6.8e-34 117.6 1.2 1.1e-33 117.0 1.2 1.3 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen FYRC PF05965.14 CDJ41971.1 - 0.12 12.6 0.0 21 5.3 0.0 2.3 2 0 0 2 2 2 0 F/Y rich C-terminus Surface_antigen PF11054.8 CDJ41972.1 - 1.3e-33 116.7 2.8 1.7e-33 116.3 2.8 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen FYRC PF05965.14 CDJ41972.1 - 0.066 13.4 0.0 0.9 9.7 0.0 2.3 2 0 0 2 2 2 0 F/Y rich C-terminus Surface_antigen PF11054.8 CDJ41973.1 - 3.8e-30 105.4 0.3 5.9e-30 104.7 0.3 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen FYRC PF05965.14 CDJ41973.1 - 0.15 12.3 0.0 11 6.3 0.0 2.3 2 0 0 2 2 2 0 F/Y rich C-terminus Surface_antigen PF11054.8 CDJ41974.1 - 4.1e-28 98.7 1.4 6e-28 98.2 1.4 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ41975.1 - 1.3e-33 116.7 1.6 1.7e-33 116.3 1.6 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ41976.1 - 5.5e-31 108.1 0.7 7.4e-31 107.7 0.7 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ41977.1 - 6.1e-31 108.0 0.7 8.7e-31 107.5 0.7 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Equine_IAV_S2 PF06502.11 CDJ41977.1 - 0.08 13.0 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Equine infectious anaemia virus S2 protein Surface_antigen PF11054.8 CDJ41978.1 - 1.1e-33 116.9 1.3 1.4e-33 116.6 1.3 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Peptidase_S9_N PF02897.15 CDJ41978.1 - 0.045 12.5 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Surface_antigen PF11054.8 CDJ41979.1 - 1.5e-25 90.3 1.9 1e-24 87.6 1.9 2.0 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Tom7 PF08038.12 CDJ41979.1 - 0.17 11.6 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 TOM7 family CHASE4 PF05228.13 CDJ41979.1 - 0.22 11.7 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 CHASE4 domain Surface_antigen PF11054.8 CDJ41980.1 - 1.2e-33 116.9 3.2 1.5e-33 116.5 3.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF3982 PF13138.6 CDJ41980.1 - 0.089 12.6 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) Surface_antigen PF11054.8 CDJ41981.1 - 4.3e-30 105.2 0.9 6.9e-30 104.5 0.9 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ41982.1 - 3.3e-34 118.6 1.7 1.1e-33 116.9 1.7 1.7 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Coronavirus_5 PF05528.11 CDJ41982.1 - 0.029 14.4 0.1 0.059 13.3 0.0 1.6 2 0 0 2 2 2 0 Coronavirus gene 5 protein Surface_antigen PF11054.8 CDJ41983.1 - 4e-27 95.4 4.5 3.1e-26 92.5 4.6 1.9 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ41984.1 - 1.2e-27 97.1 1.1 1.4e-27 96.9 1.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Retrotrans_gag PF03732.17 CDJ41985.1 - 0.00062 20.0 0.4 0.0014 18.9 0.0 1.7 3 0 0 3 3 3 1 Retrotransposon gag protein Retrotrans_gag PF03732.17 CDJ41988.1 - 0.0055 17.0 0.8 0.0055 17.0 0.8 1.9 3 1 0 3 3 3 1 Retrotransposon gag protein Sec20 PF03908.13 CDJ41989.1 - 0.00031 20.6 18.5 0.0025 17.7 1.8 3.8 4 0 0 4 4 4 2 Sec20 HupE_UreJ_2 PF13795.6 CDJ41989.1 - 0.2 11.3 2.0 0.41 10.3 2.0 1.5 1 0 0 1 1 1 0 HupE / UreJ protein ARGLU PF15346.6 CDJ41989.1 - 2.2 8.1 11.2 0.29 11.0 0.2 2.5 3 0 0 3 3 3 0 Arginine and glutamate-rich 1 Exonuc_VII_L PF02601.15 CDJ41989.1 - 9.3 5.7 16.0 3.4 7.1 0.1 2.6 2 1 0 2 2 2 0 Exonuclease VII, large subunit Surface_antigen PF11054.8 CDJ41990.1 - 4.9e-28 98.4 0.1 5.9e-28 98.2 0.1 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ41991.1 - 1.2e-09 38.2 0.6 4e-06 26.7 0.4 2.1 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ41992.1 - 3.2e-22 79.4 1.8 4.5e-18 65.8 0.3 2.1 2 0 0 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ41993.1 - 1.5e-30 106.7 0.7 2.2e-30 106.1 0.7 1.3 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ41994.1 - 1e-20 74.4 0.1 1.2e-20 74.2 0.1 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ41995.1 - 9.5e-34 117.2 1.2 1.4e-33 116.6 1.2 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ41996.1 - 7.9e-33 114.1 0.7 9.4e-33 113.9 0.7 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ41997.1 - 1.5e-29 103.4 1.1 3e-29 102.4 1.1 1.4 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Acetyltransf_1 PF00583.25 CDJ41998.1 - 6.9e-11 42.4 0.0 1.3e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ41998.1 - 6.7e-08 32.9 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ41998.1 - 4.1e-06 26.7 0.0 7.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4603 PF15376.6 CDJ41998.1 - 0.045 11.2 9.8 0.058 10.8 9.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) IMUP PF15761.5 CDJ41998.1 - 0.15 12.7 9.1 0.34 11.6 9.1 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein NAM-associated PF14303.6 CDJ41998.1 - 0.29 11.9 5.9 0.44 11.3 5.9 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Presenilin PF01080.17 CDJ41998.1 - 1 8.0 3.9 1.8 7.3 3.9 1.3 1 1 0 1 1 1 0 Presenilin SNARE_assoc PF09335.11 CDJ42000.1 - 3.6e-14 53.3 8.2 3.6e-14 53.3 8.2 2.5 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF3087 PF11286.8 CDJ42000.1 - 0.14 11.6 1.7 7.9 5.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) FAD-oxidase_C PF02913.19 CDJ42001.1 - 3.1e-38 131.8 0.0 4.5e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CDJ42001.1 - 2.8e-33 114.6 0.5 4.9e-33 113.8 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain zf-U11-48K PF05253.12 CDJ42002.1 - 4e-06 26.6 0.2 9.3e-06 25.4 0.2 1.7 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger TRM13 PF05206.14 CDJ42002.1 - 8.2e-06 25.5 8.1 0.00059 19.5 0.0 3.8 4 1 0 4 4 4 2 Methyltransferase TRM13 Radial_spoke_3 PF06098.11 CDJ42003.1 - 1.1e-07 31.5 10.8 2.9e-07 30.0 10.8 1.7 1 0 0 1 1 1 1 Radial spoke protein 3 DUF842 PF05811.13 CDJ42003.1 - 0.017 14.8 1.5 0.047 13.4 0.0 2.3 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) DUF2335 PF10097.9 CDJ42003.1 - 3.3 7.7 9.1 3.1 7.8 0.0 3.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2335) CBM_19 PF03427.13 CDJ42006.1 - 0.034 14.1 0.2 0.052 13.5 0.2 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) EGF_2 PF07974.13 CDJ42008.1 - 0.67 10.4 37.6 0.25 11.7 6.6 3.9 3 0 0 3 3 3 0 EGF-like domain U-box PF04564.15 CDJ42009.1 - 3.8e-18 65.4 0.0 7.5e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 CDJ42009.1 - 1.3e-10 40.6 7.7 0.0013 18.4 1.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ42009.1 - 6.6e-10 38.3 8.9 0.0074 16.3 1.8 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ42009.1 - 8.6e-07 28.7 7.3 0.016 15.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ42009.1 - 1.8e-05 25.3 6.3 0.0003 21.4 2.4 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ42009.1 - 3.6e-05 23.9 1.3 7.5e-05 22.9 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CDJ42009.1 - 4.6e-05 23.5 2.9 0.00019 21.5 0.5 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ42009.1 - 0.00032 20.9 9.6 0.086 13.1 0.5 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ42009.1 - 0.011 16.2 3.3 0.037 14.6 1.6 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-NOSIP PF15906.5 CDJ42009.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_11 PF13414.6 CDJ42009.1 - 0.014 15.0 7.5 2.1 8.1 1.3 3.2 1 1 2 3 3 3 0 TPR repeat HTH_17 PF12728.7 CDJ42009.1 - 0.037 14.2 0.2 0.078 13.2 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_14 PF13428.6 CDJ42009.1 - 1.1 10.3 10.5 3.8 8.6 0.0 4.2 2 2 3 5 5 4 0 Tetratricopeptide repeat SPX PF03105.19 CDJ42009.1 - 2.3 8.1 7.6 3.2 7.6 7.6 1.3 1 0 0 1 1 1 0 SPX domain ubiquitin PF00240.23 CDJ42011.1 - 2.6e-34 116.8 0.3 3.6e-34 116.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CDJ42011.1 - 5.9e-30 102.9 11.2 9e-30 102.3 11.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CDJ42011.1 - 6.8e-17 61.1 0.5 1e-16 60.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ42011.1 - 3.3e-06 27.5 0.1 1.2e-05 25.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ42011.1 - 0.004 17.1 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CDJ42011.1 - 0.011 16.1 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ42011.1 - 0.013 15.5 0.0 0.03 14.4 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CDJ42011.1 - 0.025 14.6 0.8 5.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CDJ42011.1 - 0.044 14.4 0.0 0.053 14.1 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Vac14_Fab1_bd PF12755.7 CDJ42012.1 - 6.7e-33 113.2 0.0 1.5e-28 99.2 0.0 4.4 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.8 CDJ42012.1 - 9.4e-17 61.2 0.0 2.5e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.22 CDJ42012.1 - 2.1e-10 39.9 0.6 0.018 15.3 0.0 5.1 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.6 CDJ42012.1 - 1e-05 25.9 1.5 0.19 12.2 0.0 4.9 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 CDJ42012.1 - 0.00058 20.2 2.5 0.58 10.6 0.1 5.1 3 2 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 CDJ42012.1 - 0.0013 18.8 0.0 1.4 8.9 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 CDJ42012.1 - 0.051 13.1 0.7 1.4 8.4 0.1 3.1 3 0 0 3 3 3 0 Tti2 family HA2 PF04408.23 CDJ42012.1 - 0.071 13.4 3.9 0.6 10.4 2.1 3.1 2 1 0 2 2 2 0 Helicase associated domain (HA2) PPR PF01535.20 CDJ42013.1 - 6.4e-14 51.1 1.8 0.00057 20.0 0.1 6.2 7 0 0 7 7 7 2 PPR repeat PPR_2 PF13041.6 CDJ42013.1 - 1.3e-13 50.9 0.0 1e-05 25.6 0.0 4.4 3 1 2 5 5 5 2 PPR repeat family PPR_long PF17177.4 CDJ42013.1 - 2.4e-05 23.8 0.1 2.4e-05 23.8 0.1 3.9 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CDJ42013.1 - 9.8e-05 22.4 0.0 1.7 8.8 0.0 4.9 4 1 1 5 5 5 2 Pentatricopeptide repeat domain Vir_act_alpha_C PF10400.9 CDJ42013.1 - 0.06 14.0 0.3 0.06 14.0 0.3 5.8 4 3 2 6 6 6 0 Virulence activator alpha C-term PrpF PF04303.13 CDJ42013.1 - 0.22 10.4 2.3 0.52 9.2 2.3 1.5 1 0 0 1 1 1 0 PrpF protein YjbH PF06082.11 CDJ42013.1 - 0.51 9.1 10.6 0.02 13.7 4.5 1.7 2 0 0 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH TPR_7 PF13176.6 CDJ42013.1 - 1.2 9.3 4.1 4.4 7.6 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat SF3A2 PF16835.5 CDJ42014.1 - 8.5e-36 122.2 0.0 1.3e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CDJ42014.1 - 3.3e-07 30.5 1.4 6.1e-07 29.6 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 CDJ42014.1 - 0.0093 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein ABC_tran PF00005.27 CDJ42015.1 - 5.5e-24 85.2 0.0 8.8e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 CDJ42015.1 - 7.9e-20 71.2 23.2 4.9e-17 62.0 19.0 2.5 1 1 1 2 2 2 2 ABC-2 type transporter ABC2_membrane_3 PF12698.7 CDJ42015.1 - 9.2e-10 38.1 11.1 1.4e-09 37.6 11.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ42015.1 - 2.8e-05 24.1 0.2 0.018 14.9 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CDJ42015.1 - 0.00014 21.8 0.1 0.00026 20.9 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CDJ42015.1 - 0.00024 21.5 0.0 0.00055 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CDJ42015.1 - 0.00048 19.7 0.2 0.0028 17.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDJ42015.1 - 0.0015 18.2 0.2 0.0035 17.1 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ42015.1 - 0.0033 17.5 0.1 0.0064 16.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 CDJ42015.1 - 0.004 17.7 0.0 0.0088 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 CDJ42015.1 - 0.021 14.9 0.7 0.041 14.0 0.7 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain ABC2_membrane_2 PF12679.7 CDJ42015.1 - 0.022 14.0 5.5 0.034 13.4 5.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein IstB_IS21 PF01695.17 CDJ42015.1 - 0.023 14.5 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein MeaB PF03308.16 CDJ42015.1 - 0.024 13.6 1.0 0.035 13.1 0.2 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 CDJ42015.1 - 0.05 13.8 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ42015.1 - 0.051 12.9 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 CDJ42015.1 - 0.059 13.1 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 CDJ42015.1 - 0.22 10.9 0.0 2.8 7.3 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DGF-1_C PF11040.8 CDJ42018.1 - 0.0071 16.3 4.3 0.0084 16.1 3.0 1.8 1 1 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF4663 PF15668.5 CDJ42018.1 - 1.4 7.9 7.8 1.1 8.3 6.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4663) Glyoxalase PF00903.25 CDJ42019.1 - 2.4e-11 44.0 0.0 1.2e-07 32.0 0.0 3.1 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CDJ42019.1 - 0.00019 21.6 0.0 0.11 12.8 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Peptidase_M41 PF01434.18 CDJ42020.1 - 2.6e-52 177.4 0.1 9.7e-52 175.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 CDJ42020.1 - 1.1e-41 142.3 0.0 2.2e-41 141.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ42020.1 - 7e-13 48.2 0.5 1.6e-12 47.0 0.5 1.7 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 CDJ42020.1 - 0.00047 19.5 0.0 0.00081 18.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CDJ42020.1 - 0.00053 20.3 1.4 0.15 12.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 CDJ42020.1 - 0.0033 17.4 0.0 0.0099 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CDJ42020.1 - 0.0064 17.0 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDJ42020.1 - 0.0082 15.9 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ42020.1 - 0.0086 16.5 0.2 0.0086 16.5 0.2 2.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 CDJ42020.1 - 0.017 15.3 0.0 0.07 13.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CDJ42020.1 - 0.023 14.4 0.0 0.08 12.7 0.0 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CDJ42020.1 - 0.024 14.0 0.5 0.14 11.5 0.2 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 CDJ42020.1 - 0.12 12.5 0.0 0.48 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 CDJ42020.1 - 0.43 10.8 0.0 0.43 10.8 0.0 2.4 3 0 0 3 3 1 0 AAA domain DUF4837 PF16125.5 CDJ42020.1 - 0.59 9.1 5.7 5.7 5.9 5.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4837) AAA_11 PF13086.6 CDJ42020.1 - 5.2 6.8 10.6 11 5.7 0.1 3.3 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 CDJ42021.1 - 6.4e-35 120.5 0.0 2.2e-24 86.2 0.0 2.5 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ42021.1 - 2e-24 86.1 0.0 4.9e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ42021.1 - 0.00021 21.3 0.0 0.00054 20.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ42021.1 - 0.035 14.4 0.1 5.4 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain RES PF08808.11 CDJ42021.1 - 0.057 13.3 1.5 0.13 12.1 0.1 2.4 3 0 0 3 3 3 0 RES domain DUF2730 PF10805.8 CDJ42022.1 - 0.017 15.2 0.1 0.029 14.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) EMG1 PF03587.14 CDJ42023.1 - 1.3e-45 155.5 0.2 1.5e-45 155.2 0.2 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase BAF1_ABF1 PF04684.13 CDJ42024.1 - 1.4 7.9 22.4 1.7 7.6 22.4 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor zf-RING_2 PF13639.6 CDJ42026.1 - 3.4e-09 36.9 11.8 6.9e-09 35.9 11.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CDJ42026.1 - 3.4e-06 27.2 9.7 8.5e-06 26.0 9.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CDJ42026.1 - 3.8e-06 26.5 0.8 8.6e-06 25.4 0.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDJ42026.1 - 2.1e-05 24.2 11.0 4.2e-05 23.3 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ42026.1 - 0.00032 20.5 6.1 0.00073 19.3 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ42026.1 - 0.00066 19.7 2.7 0.0015 18.5 2.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ42026.1 - 0.0018 18.1 7.8 0.0038 17.0 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ42026.1 - 0.0066 16.4 9.3 0.013 15.5 9.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CDJ42026.1 - 0.019 14.6 9.8 0.04 13.5 9.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CDJ42026.1 - 0.061 13.4 4.8 0.11 12.5 4.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 CDJ42026.1 - 0.11 12.7 6.7 0.24 11.6 6.7 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF1272 PF06906.11 CDJ42026.1 - 2 8.6 7.1 5.3 7.2 7.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING-like PF08746.11 CDJ42026.1 - 5.6 7.4 8.5 12 6.3 8.5 1.6 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 CDJ42026.1 - 7 6.5 8.4 17 5.3 8.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2975 PF11188.8 CDJ42027.1 - 0.028 14.3 0.5 0.074 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) LapA_dom PF06305.11 CDJ42027.1 - 0.031 14.1 0.0 0.031 14.1 0.0 2.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain TMEM100 PF16311.5 CDJ42027.1 - 0.039 13.5 0.1 0.07 12.7 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 DUF4658 PF15555.6 CDJ42027.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Ninjurin PF04923.12 CDJ42027.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Ninjurin SIT PF15330.6 CDJ42027.1 - 0.19 12.2 0.7 0.39 11.2 0.7 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4064 PF13273.6 CDJ42027.1 - 0.21 11.9 1.3 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) LMBR1 PF04791.16 CDJ42028.1 - 1.7e-07 30.5 0.0 1.7e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 LMBR1-like membrane protein DUF1180 PF06679.12 CDJ42028.1 - 0.0071 16.8 10.9 0.35 11.3 1.9 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1180) DUF4381 PF14316.6 CDJ42028.1 - 0.078 13.2 0.5 0.078 13.2 0.5 4.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4381) DUF5357 PF17310.2 CDJ42028.1 - 0.36 9.3 1.5 0.71 8.4 1.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Peptidase_S8 PF00082.22 CDJ42029.1 - 3.8e-42 144.6 6.0 9.4e-42 143.3 6.0 1.7 1 0 0 1 1 1 1 Subtilase family UPF0051 PF01458.17 CDJ42031.1 - 8.8e-45 153.1 0.1 1.4e-44 152.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Med17 PF10156.9 CDJ42031.1 - 0.0025 16.6 2.4 0.0041 15.9 0.1 2.0 2 0 0 2 2 2 1 Subunit 17 of Mediator complex Avidin PF01382.17 CDJ42031.1 - 0.053 14.0 0.6 0.13 12.7 0.6 1.6 1 0 0 1 1 1 0 Avidin family TFIIA PF03153.13 CDJ42032.1 - 0.96 9.4 17.8 0.12 12.3 13.6 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NUP PF06516.11 CDJ42032.1 - 1.9 7.7 5.7 0.74 9.0 0.9 2.3 3 0 0 3 3 3 0 Purine nucleoside permease (NUP) Spt20 PF12090.8 CDJ42032.1 - 4.6 6.8 18.1 8.6 5.9 18.1 1.4 1 0 0 1 1 1 0 Spt20 family HJURP_C PF12347.8 CDJ42033.1 - 0.54 10.3 4.2 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat Activator_LAG-3 PF11498.8 CDJ42033.1 - 1.5 7.7 17.7 1.7 7.5 17.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TSA PF03249.13 CDJ42033.1 - 3 6.5 14.4 1.8 7.2 13.3 1.3 1 1 0 1 1 1 0 Type specific antigen DFRP_C PF16543.5 CDJ42036.1 - 2.3e-16 60.0 1.8 2.3e-16 60.0 1.8 3.7 3 1 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 Caskin1-CID PF16600.5 CDJ42036.1 - 7.6 7.2 12.6 3 8.5 3.6 2.4 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain Coatomer_E PF04733.14 CDJ42038.1 - 5.3e-13 49.0 2.2 8.9e-13 48.3 2.2 1.3 1 0 0 1 1 1 1 Coatomer epsilon subunit Alkyl_sulf_dimr PF14863.6 CDJ42038.1 - 0.014 15.9 1.4 0.35 11.3 0.1 2.5 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_19 PF14559.6 CDJ42038.1 - 0.02 15.4 0.1 0.02 15.4 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Proteasom_PSMB PF10508.9 CDJ42038.1 - 0.023 13.2 0.6 0.04 12.4 0.4 1.4 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit TPR_7 PF13176.6 CDJ42038.1 - 0.027 14.5 5.9 0.054 13.5 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ42038.1 - 0.094 13.6 0.1 0.094 13.6 0.1 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 CDJ42041.1 - 1.7e-47 161.6 0.1 2.2e-47 161.3 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GCP_N_terminal PF17681.1 CDJ42042.1 - 1.4e-45 156.3 0.0 5.4e-45 154.3 0.0 1.8 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CDJ42042.1 - 1.8e-09 37.5 1.0 1.8e-09 37.5 1.0 2.7 3 1 0 3 3 3 1 Gamma tubulin complex component C-terminal PDT PF00800.18 CDJ42042.1 - 7.2 6.4 8.5 0.34 10.7 0.4 2.5 2 0 0 2 2 2 0 Prephenate dehydratase GCP_C_terminal PF04130.13 CDJ42043.1 - 3.9e-11 43.0 1.8 8e-11 42.0 1.8 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal HEAT_EZ PF13513.6 CDJ42043.1 - 0.07 13.7 0.2 0.07 13.7 0.2 3.0 3 1 1 4 4 4 0 HEAT-like repeat HEAT PF02985.22 CDJ42043.1 - 0.12 12.7 0.2 0.64 10.4 0.2 2.3 1 0 0 1 1 1 0 HEAT repeat Ribosomal_60s PF00428.19 CDJ42043.1 - 0.16 12.6 5.7 6.2 7.5 0.4 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein PPC PF04151.15 CDJ42043.1 - 0.25 12.5 0.6 49 5.1 0.0 2.6 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain Peptidase_M17_N PF02789.17 CDJ42043.1 - 0.52 10.2 5.8 1.8 8.5 1.4 2.6 2 1 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain SUIM_assoc PF16619.5 CDJ42043.1 - 1.1 9.3 10.1 1.7 8.8 6.3 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-Mss51 PF13824.6 CDJ42044.1 - 0.57 10.3 6.3 0.43 10.7 0.2 3.9 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 TctA PF01970.16 CDJ42045.1 - 0.02 13.6 0.3 0.02 13.6 0.3 1.6 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctA family Patched PF02460.18 CDJ42045.1 - 0.065 11.3 0.0 0.093 10.8 0.0 1.1 1 0 0 1 1 1 0 Patched family DUF2530 PF10745.9 CDJ42045.1 - 0.14 12.4 0.9 0.57 10.4 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) PARM PF17061.5 CDJ42045.1 - 0.16 12.1 10.7 0.25 11.5 10.7 1.2 1 0 0 1 1 1 0 PARM DUF4064 PF13273.6 CDJ42045.1 - 1.1 9.5 5.3 6.6 7.1 0.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF4131 PF13567.6 CDJ42045.1 - 4.7 6.8 5.6 1.1 8.9 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) HAP1_N PF04849.13 CDJ42046.1 - 0.78 8.9 23.8 0.044 13.0 10.3 2.4 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Adap_comp_sub PF00928.21 CDJ42047.1 - 1.5e-09 37.7 0.0 2.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDJ42047.1 - 0.22 11.4 0.6 0.77 9.7 0.2 2.0 2 0 0 2 2 2 0 Clathrin adaptor complex small chain PK PF00224.21 CDJ42048.1 - 1.6e-145 484.4 0.6 2.1e-145 484.0 0.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CDJ42048.1 - 4.5e-32 110.7 0.4 1.1e-31 109.5 0.4 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CDJ42048.1 - 0.0046 16.1 1.1 0.011 14.9 0.1 2.1 2 1 1 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family Vps8 PF12816.7 CDJ42048.1 - 0.041 13.4 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 Dor1 PF04124.12 CDJ42049.1 - 1.5e-23 83.0 1.8 2.3e-23 82.4 1.8 1.2 1 0 0 1 1 1 1 Dor1-like family Exo84_C PF16528.5 CDJ42049.1 - 1.3e-05 25.1 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CDJ42049.1 - 0.026 14.6 0.1 0.077 13.1 0.1 1.8 1 0 0 1 1 1 0 Vps51/Vps67 Sec1 PF00995.23 CDJ42050.1 - 4.1e-80 270.7 0.6 5e-80 270.4 0.6 1.0 1 0 0 1 1 1 1 Sec1 family YlbD_coat PF14071.6 CDJ42050.1 - 0.08 13.2 0.3 0.38 11.0 0.3 1.9 2 0 0 2 2 2 0 Putative coat protein Sec1 PF00995.23 CDJ42051.1 - 7.9e-16 58.4 0.0 8.2e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PEP_hydrolase PF09370.10 CDJ42051.1 - 0.078 12.2 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like DSPc PF00782.20 CDJ42053.1 - 9.6e-25 86.9 0.0 1.4e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain HTH_32 PF13565.6 CDJ42053.1 - 0.00052 20.6 0.0 0.0018 18.8 0.0 2.0 1 0 0 1 1 1 1 Homeodomain-like domain PTPlike_phytase PF14566.6 CDJ42053.1 - 0.0013 18.9 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CDJ42053.1 - 0.0015 18.1 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Proteasome PF00227.26 CDJ42054.1 - 5.1e-59 199.0 0.0 6.3e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ42054.1 - 2.1e-13 49.7 0.2 3.4e-13 49.0 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GM_CSF PF01109.17 CDJ42054.1 - 0.023 14.9 0.2 0.049 13.8 0.1 1.6 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor Ribosomal_S26e PF01283.19 CDJ42055.1 - 4.8e-49 165.3 9.2 5.8e-49 165.0 9.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e SRP19 PF01922.17 CDJ42055.1 - 0.041 14.8 0.2 0.059 14.3 0.2 1.3 1 0 0 1 1 1 0 SRP19 protein JAB PF01398.21 CDJ42056.1 - 5.4e-28 97.3 0.0 1.5e-27 95.9 0.0 1.7 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CDJ42056.1 - 8.6e-06 25.5 0.0 4.6e-05 23.2 0.0 2.2 2 1 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CDJ42056.1 - 0.03 14.4 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF2615 PF11027.8 CDJ42059.1 - 0.13 12.4 0.3 0.8 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Autophagy_act_C PF03987.15 CDJ42060.1 - 1.4e-21 76.8 0.3 2e-21 76.3 0.3 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CDJ42060.1 - 3.6e-13 48.7 2.4 6.1e-13 48.0 2.4 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Use1 PF09753.9 CDJ42061.1 - 0.0008 19.2 9.2 0.0013 18.5 9.2 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 CDJ42061.1 - 0.0093 16.0 0.6 0.018 15.0 0.6 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin-6_N PF09177.11 CDJ42061.1 - 0.023 15.3 0.4 0.023 15.3 0.4 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4577 PF15145.6 CDJ42061.1 - 0.047 13.7 0.4 0.078 13.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DUF2218 PF09981.9 CDJ42061.1 - 0.13 12.6 1.8 4.6 7.7 0.1 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) Med15 PF09606.10 CDJ42061.1 - 0.31 9.7 11.8 0.065 11.9 3.8 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal PDDEXK_6 PF04720.12 CDJ42061.1 - 0.63 9.9 4.5 0.19 11.6 0.8 1.9 2 0 0 2 2 2 0 PDDEXK-like family of unknown function DUF4407 PF14362.6 CDJ42061.1 - 1.4 8.2 14.9 1.9 7.8 6.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) CCDC-167 PF15188.6 CDJ42061.1 - 3.3 8.1 11.3 0.21 11.9 4.4 2.5 3 1 0 3 3 2 0 Coiled-coil domain-containing protein 167 FliD_N PF02465.18 CDJ42061.1 - 5.7 7.7 15.8 17 6.2 0.3 3.2 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF2721 PF11026.8 CDJ42061.1 - 5.8 6.8 13.0 2.3 8.1 1.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Tropomyosin PF00261.20 CDJ42061.1 - 6.2 6.1 14.5 7.4 5.9 1.0 2.2 2 0 0 2 2 2 0 Tropomyosin Myosin_head PF00063.21 CDJ42062.1 - 9.4e-173 576.0 0.0 1.2e-172 575.7 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 CDJ42062.1 - 0.0092 16.4 0.0 0.0092 16.4 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain T2SSE PF00437.20 CDJ42062.1 - 0.031 13.3 0.0 0.093 11.8 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 CDJ42062.1 - 0.063 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDJ42062.1 - 0.097 12.9 1.0 0.3 11.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CDJ42062.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter COG6 PF06419.11 CDJ42063.1 - 2.5e-07 29.4 12.9 8.5e-06 24.3 12.9 2.6 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 FAD-oxidase_C PF02913.19 CDJ42063.1 - 0.24 11.0 3.0 1.3 8.6 0.2 2.6 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain MethyTransf_Reg PF10119.9 CDJ42063.1 - 0.41 11.4 11.1 0.56 10.9 0.2 3.8 3 0 0 3 3 3 0 Predicted methyltransferase regulatory domain NOG1 PF06858.14 CDJ42063.1 - 1.3 8.9 6.3 0.72 9.7 0.1 3.2 3 0 0 3 3 3 0 Nucleolar GTP-binding protein 1 (NOG1) CP12 PF02672.15 CDJ42063.1 - 9.6 7.0 8.4 0.98 10.2 0.9 3.1 2 0 0 2 2 2 0 CP12 domain GCV_H PF01597.19 CDJ42064.1 - 1.7e-21 76.4 0.0 2.1e-17 63.1 0.0 2.2 2 0 0 2 2 2 2 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 CDJ42064.1 - 0.0021 17.8 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme SPX PF03105.19 CDJ42064.1 - 0.26 11.2 3.6 0.35 10.8 3.6 1.1 1 0 0 1 1 1 0 SPX domain SpoU_methylase PF00588.19 CDJ42065.1 - 6.4e-06 26.4 0.0 1.8e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 SpoU rRNA Methylase family MgtE_N PF03448.17 CDJ42068.1 - 0.14 12.8 5.4 0.18 12.4 5.4 1.1 1 0 0 1 1 1 0 MgtE intracellular N domain Ion_trans PF00520.31 CDJ42068.1 - 0.57 9.4 3.5 1.5 8.0 3.5 1.7 1 1 0 1 1 1 0 Ion transport protein Pkinase PF00069.25 CDJ42069.1 - 1e-76 257.8 0.0 1.3e-76 257.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ42069.1 - 1.4e-34 119.6 0.0 2e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ42069.1 - 1.3e-27 93.3 8.8 7.1e-07 28.3 0.0 4.9 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ42069.1 - 2.9e-24 85.3 3.0 8.1e-13 48.6 1.4 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ42069.1 - 2.7e-23 81.5 10.2 1.5e-07 31.1 1.3 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ42069.1 - 8.9e-23 78.2 8.0 7.1e-06 25.5 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CDJ42069.1 - 7.1e-22 75.9 9.9 4e-07 29.2 0.1 4.9 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.6 CDJ42069.1 - 3.5e-07 30.4 0.4 0.0021 18.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDJ42069.1 - 1.6e-05 24.8 1.5 0.12 12.4 0.6 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.6 CDJ42069.1 - 6.2e-05 22.5 0.0 0.0042 16.4 0.0 2.3 1 1 1 2 2 2 1 Kinase-like SPARC_Ca_bdg PF10591.9 CDJ42069.1 - 9.8e-05 22.6 0.2 0.33 11.3 0.0 2.6 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.23 CDJ42069.1 - 0.015 15.3 3.1 0.11 12.4 0.0 3.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family ABC1 PF03109.16 CDJ42069.1 - 0.051 13.7 0.0 0.38 10.9 0.0 2.2 2 0 0 2 2 2 0 ABC1 family Kdo PF06293.14 CDJ42069.1 - 0.078 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_2 PF02230.16 CDJ42070.1 - 1.6e-37 129.5 0.0 2.5e-36 125.5 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CDJ42070.1 - 6.7e-09 35.7 0.0 1.3e-08 34.7 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 CDJ42070.1 - 9.4e-06 26.4 0.4 1.4e-05 25.8 0.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CDJ42070.1 - 0.00031 20.7 0.1 0.00063 19.7 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ42070.1 - 0.00072 19.1 0.3 1.1 8.6 0.1 2.6 1 1 1 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CDJ42070.1 - 0.0051 16.1 0.5 0.97 8.6 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Esterase_phd PF10503.9 CDJ42070.1 - 0.014 14.9 0.1 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF2974 PF11187.8 CDJ42070.1 - 0.022 14.3 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 CDJ42070.1 - 0.028 14.1 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 CDJ42070.1 - 0.086 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II GTP_EFTU PF00009.27 CDJ42071.1 - 2e-14 53.6 0.3 2e-14 53.6 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CDJ42071.1 - 6.6e-11 42.3 0.0 1.4e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 RsgA_GTPase PF03193.16 CDJ42071.1 - 0.15 12.0 4.0 0.34 10.8 0.2 2.7 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 CDJ42071.1 - 0.17 12.3 0.1 0.68 10.4 0.1 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 CDJ42071.1 - 0.43 10.2 2.4 0.26 10.9 0.3 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF4651 PF15513.6 CDJ42072.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) RRM_1 PF00076.22 CDJ42072.1 - 0.16 11.8 0.0 9.7 6.1 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RdRP PF05183.12 CDJ42073.1 - 5.7e-18 64.9 0.0 6.4e-16 58.1 0.0 2.0 1 1 1 2 2 2 2 RNA dependent RNA polymerase DUF4148 PF13663.6 CDJ42073.1 - 0.021 15.0 4.0 0.021 15.0 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Peptidase_M18 PF02127.15 CDJ42073.1 - 0.29 9.9 0.0 0.41 9.4 0.0 1.1 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) RdRP PF05183.12 CDJ42074.1 - 4.9e-21 75.0 0.6 2.8e-10 39.5 0.0 2.5 3 0 0 3 3 3 2 RNA dependent RNA polymerase DUF3452 PF11934.8 CDJ42074.1 - 0.35 10.4 1.1 1.1 8.8 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) TRAPP PF04051.16 CDJ42076.1 - 7.6e-31 106.8 0.0 2.3e-30 105.2 0.0 1.7 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Macoilin PF09726.9 CDJ42077.1 - 1.2 7.6 3.1 1.8 7.0 3.1 1.2 1 0 0 1 1 1 0 Macoilin family CDC73_C PF05179.14 CDJ42078.1 - 5e-33 114.0 0.0 8.7e-33 113.2 0.0 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Treslin_N PF15292.6 CDJ42078.1 - 0.18 10.1 0.1 0.26 9.6 0.1 1.1 1 0 0 1 1 1 0 Treslin N-terminus AF-4 PF05110.13 CDJ42078.1 - 0.98 7.4 4.4 1.5 6.8 4.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Helicase_C_2 PF13307.6 CDJ42079.1 - 4.5e-40 137.6 0.1 4.5e-40 137.6 0.1 2.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 CDJ42079.1 - 4.3e-24 85.1 13.9 1.7e-19 70.1 0.0 4.1 4 0 0 4 4 4 2 DEAD_2 DEAD PF00270.29 CDJ42079.1 - 0.021 14.6 10.2 0.029 14.2 0.0 3.4 3 1 0 3 3 3 0 DEAD/DEAH box helicase DEAD PF00270.29 CDJ42080.1 - 5.1e-15 55.7 0.0 1.3e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ42080.1 - 5.7e-14 52.4 0.0 1.5e-12 47.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CDJ42080.1 - 5.3e-10 39.9 0.3 5.3e-10 39.9 0.3 3.0 3 0 0 3 3 3 1 RecQ zinc-binding ResIII PF04851.15 CDJ42080.1 - 8.3e-06 25.9 0.2 0.00011 22.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RQC PF09382.10 CDJ42080.1 - 0.00017 21.4 0.0 0.0005 19.8 0.0 1.8 1 0 0 1 1 1 1 RQC domain AAA_22 PF13401.6 CDJ42080.1 - 0.037 14.3 0.3 0.18 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain MCM_lid PF17855.1 CDJ42080.1 - 0.054 13.9 1.2 0.31 11.5 1.2 2.3 1 0 0 1 1 1 0 MCM AAA-lid domain Thymidylate_kin PF02223.17 CDJ42080.1 - 0.81 9.3 4.4 0.13 11.9 0.3 1.8 2 0 0 2 2 2 0 Thymidylate kinase DUF1168 PF06658.12 CDJ42080.1 - 5.5 6.8 16.6 5.2 6.9 4.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) MORN PF02493.20 CDJ42081.1 - 2.4e-91 294.4 101.0 4.6e-09 35.6 3.0 14.3 14 0 0 14 14 14 14 MORN repeat DUF2859 PF11072.8 CDJ42082.1 - 0.13 12.0 2.7 0.18 11.5 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2859) F-box-like PF12937.7 CDJ42083.1 - 0.14 12.1 1.6 0.93 9.4 0.3 2.6 2 0 0 2 2 2 0 F-box-like Serpin PF00079.20 CDJ42085.1 - 4.4e-77 259.9 0.5 5.4e-77 259.6 0.5 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Methyltransf_3 PF01596.17 CDJ42086.1 - 0.058 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.13 CDJ42086.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_S8 PF00082.22 CDJ42087.1 - 2.4e-10 40.2 0.1 3.7e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Subtilase family AP2 PF00847.20 CDJ42088.1 - 0.0003 20.9 1.5 0.0008 19.6 1.5 1.8 1 0 0 1 1 1 1 AP2 domain ArfGap PF01412.18 CDJ42090.1 - 3.9e-41 139.8 0.0 9.2e-41 138.6 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SUIM_assoc PF16619.5 CDJ42090.1 - 3 8.0 30.5 3.3 7.9 9.7 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Shadoo PF14999.6 CDJ42091.1 - 2.2 8.4 20.3 0.55 10.3 13.6 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective PCI PF01399.27 CDJ42092.1 - 1.8e-16 60.5 0.1 1.5e-15 57.5 0.0 2.3 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 CDJ42092.1 - 3.8e-12 46.1 1.1 9.4e-12 44.8 1.1 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF2379 PF09543.10 CDJ42092.1 - 0.44 10.7 6.0 1.8 8.8 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2379) PIGA PF08288.12 CDJ42093.1 - 3.7e-38 130.0 3.7 9.8e-38 128.6 3.7 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CDJ42093.1 - 2.7e-27 95.8 4.5 5e-27 95.0 4.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CDJ42093.1 - 9.8e-24 83.8 0.0 1.7e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ42093.1 - 1.3e-21 77.4 0.0 2.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CDJ42093.1 - 1.6e-13 51.4 0.2 1.1e-12 48.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CDJ42093.1 - 6.1e-07 29.6 0.4 9.4e-07 28.9 0.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 CDJ42093.1 - 7e-05 23.1 0.0 0.00018 21.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 CKS PF01111.19 CDJ42094.1 - 1.9e-21 76.1 0.0 3.8e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Ligase_CoA PF00549.19 CDJ42094.1 - 0.44 10.4 3.2 1.8 8.4 0.5 2.4 2 0 0 2 2 2 0 CoA-ligase PP2C PF00481.21 CDJ42096.1 - 6.7e-37 127.5 0.0 9e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ42096.1 - 0.0022 17.7 0.0 0.0077 15.9 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ42096.1 - 0.025 14.5 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) YjgF_endoribonc PF14588.6 CDJ42096.1 - 0.091 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Peptidase_C2 PF00648.21 CDJ42097.1 - 3.9e-37 127.9 0.0 9e-36 123.4 0.0 2.5 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CDJ42097.1 - 5.1e-10 39.8 3.2 7.5e-05 23.0 0.1 4.3 3 1 1 4 4 4 3 Calpain large subunit, domain III Gpi16 PF04113.14 CDJ42098.1 - 3.7e-33 114.8 5.9 8.7e-24 83.9 6.7 2.9 2 1 0 2 2 2 2 Gpi16 subunit, GPI transamidase component DNA_topoisoIV PF00521.20 CDJ42099.1 - 3.3 6.5 11.1 5.2 5.8 11.1 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A MutS_V PF00488.21 CDJ42101.1 - 2.2e-77 259.4 1.8 1.8e-76 256.4 0.1 2.3 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CDJ42101.1 - 2.3e-16 60.6 0.6 2.3e-16 60.6 0.6 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 CDJ42101.1 - 1.1e-05 25.7 2.0 2.1e-05 24.8 0.1 2.4 2 0 0 2 2 2 1 MutS family domain IV AAA_27 PF13514.6 CDJ42101.1 - 0.011 15.3 0.4 0.047 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CDJ42101.1 - 0.82 10.1 5.2 2.7 8.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF3138 PF11336.8 CDJ42101.1 - 1.3 7.6 3.7 2.7 6.5 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MMS19_N PF14500.6 CDJ42102.1 - 1.5e-27 96.9 0.0 1.5e-27 96.9 0.0 2.7 2 1 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF4064 PF13273.6 CDJ42102.1 - 0.023 15.0 1.8 1.9 8.8 0.1 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF368 PF04018.13 CDJ42102.1 - 0.13 11.9 1.1 2.3 7.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF368) RRM_1 PF00076.22 CDJ42103.1 - 9.5e-15 54.2 0.1 1.8e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CDJ42103.1 - 0.00082 19.2 0.2 0.14 12.0 0.1 2.5 1 1 1 2 2 2 2 Rrp7 RRM-like N-terminal domain HCO3_cotransp PF00955.21 CDJ42103.1 - 0.14 11.0 0.5 0.19 10.5 0.5 1.1 1 0 0 1 1 1 0 HCO3- transporter family PPL5 PF18168.1 CDJ42103.1 - 0.65 9.2 8.8 0.64 9.3 3.0 2.0 2 0 0 2 2 2 0 Prim-pol family 5 Sec62 PF03839.16 CDJ42103.1 - 0.83 9.1 10.8 0.063 12.8 4.3 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 CPSF100_C PF13299.6 CDJ42103.1 - 1.3 9.1 16.3 0.015 15.5 6.0 2.1 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal MMU163 PF17119.5 CDJ42103.1 - 1.8 7.7 6.9 0.23 10.6 2.4 1.7 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Pox_Ag35 PF03286.14 CDJ42103.1 - 2.4 7.9 13.1 0.19 11.5 3.2 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM176 PF14851.6 CDJ42103.1 - 3 7.5 10.1 4.7 6.9 2.2 2.4 2 0 0 2 2 2 0 FAM176 family Afi1 PF07792.12 CDJ42103.1 - 5.7 7.4 12.2 1.4 9.4 5.1 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NPR3 PF03666.13 CDJ42103.1 - 7.7 5.2 13.6 0.34 9.6 5.4 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 OKR_DC_1 PF01276.20 CDJ42104.1 - 5.6e-74 249.4 0.0 2e-53 181.6 0.0 2.2 1 1 0 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 CDJ42104.1 - 0.0017 17.7 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1_C PF03711.15 CDJ42104.1 - 0.011 16.0 0.1 0.026 14.8 0.1 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain PrmA PF06325.13 CDJ42105.1 - 8.4e-12 45.1 0.1 1.6e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CDJ42105.1 - 1.1e-08 35.6 0.1 3.9e-08 33.9 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ42105.1 - 5.9e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CDJ42105.1 - 1.7e-06 28.0 0.0 8.1e-06 25.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ42105.1 - 2.6e-06 27.3 0.0 1.2e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ42105.1 - 1.3e-05 25.8 0.0 7.5e-05 23.3 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain CMAS PF02353.20 CDJ42105.1 - 0.00067 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 CDJ42105.1 - 0.00081 19.3 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ42105.1 - 0.0015 17.9 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.15 CDJ42105.1 - 0.0016 18.2 0.1 0.0031 17.2 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_9 PF08003.11 CDJ42105.1 - 0.0016 17.5 0.2 0.0068 15.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 CDJ42105.1 - 0.0031 17.5 0.8 0.0099 15.9 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain PCMT PF01135.19 CDJ42105.1 - 0.013 15.2 0.1 0.023 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 CDJ42105.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TehB PF03848.14 CDJ42105.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB zf-HIT PF04438.16 CDJ42106.1 - 4.2e-05 23.3 14.6 0.00011 22.0 14.6 1.7 1 0 0 1 1 1 1 HIT zinc finger Methyltransf_23 PF13489.6 CDJ42107.1 - 8.7e-14 51.7 0.0 1.5e-13 50.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ42107.1 - 3.9e-10 40.4 0.0 6.6e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ42107.1 - 1.5e-07 32.0 0.0 0.002 18.8 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ42107.1 - 8.9e-05 23.1 0.0 0.19 12.4 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 CDJ42107.1 - 0.0021 17.6 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CDJ42107.1 - 0.0034 17.2 0.0 0.052 13.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 CDJ42107.1 - 0.031 13.8 0.0 0.076 12.5 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 CDJ42107.1 - 0.033 13.5 0.0 0.13 11.5 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain DUF3273 PF11677.8 CDJ42109.1 - 3.3e-99 331.5 6.0 3.8e-99 331.3 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Exo_endo_phos PF03372.23 CDJ42111.1 - 0.024 14.2 0.0 0.08 12.5 0.0 1.9 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family TPT PF03151.16 CDJ42112.1 - 8.9e-06 25.3 10.3 1.6e-05 24.4 10.3 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CDJ42112.1 - 0.00093 19.4 15.7 0.058 13.6 12.5 2.9 2 1 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 CDJ42112.1 - 0.062 13.3 3.0 0.12 12.4 3.0 1.5 1 0 0 1 1 1 0 Putative transmembrane family 234 TPR_17 PF13431.6 CDJ42113.1 - 0.048 14.0 0.1 0.15 12.5 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat SET PF00856.28 CDJ42113.1 - 0.12 12.8 0.0 0.46 10.8 0.0 2.2 2 1 0 2 2 2 0 SET domain Ank_2 PF12796.7 CDJ42114.1 - 9.8e-15 54.9 1.1 7.6e-14 52.1 0.9 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ42114.1 - 1.4e-14 54.2 1.2 6.6e-09 36.1 0.3 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CDJ42114.1 - 4.2e-10 39.6 8.4 0.00045 20.5 1.8 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CDJ42114.1 - 9.9e-10 37.8 5.1 0.0026 18.1 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CDJ42114.1 - 4e-09 36.5 3.1 3.5e-07 30.4 0.3 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) CRAL_TRIO_2 PF13716.6 CDJ42115.1 - 1.3e-13 51.2 0.1 2.2e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.21 CDJ42115.1 - 6.7e-07 29.4 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Macro domain Abhydrolase_1 PF00561.20 CDJ42116.1 - 8.4e-05 22.3 0.3 0.00024 20.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ42116.1 - 0.00016 21.0 0.2 0.071 12.4 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDJ42116.1 - 0.00051 20.7 1.3 0.0012 19.5 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CDJ42116.1 - 0.0012 18.7 0.0 0.012 15.5 0.0 2.3 2 0 0 2 2 2 1 Lipase (class 3) Thioesterase PF00975.20 CDJ42116.1 - 0.023 14.8 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain FSH1 PF03959.13 CDJ42116.1 - 0.082 12.6 0.0 0.55 9.9 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Shugoshin_N PF07558.11 CDJ42117.1 - 0.038 13.9 2.5 0.37 10.7 0.8 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region VPS11_C PF12451.8 CDJ42117.1 - 0.12 12.6 0.5 0.69 10.2 0.5 2.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal HOOK PF05622.12 CDJ42117.1 - 7 4.7 40.9 1.2e+02 0.6 40.9 2.3 1 1 0 1 1 1 0 HOOK protein Pkinase PF00069.25 CDJ42118.1 - 1.4e-55 188.5 10.5 4.1e-35 121.4 0.0 3.4 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ42118.1 - 7.7e-25 87.7 0.0 7.7e-25 87.7 0.0 3.5 4 0 0 4 4 4 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ42118.1 - 0.0099 14.9 0.3 0.0099 14.9 0.3 3.7 4 0 0 4 4 4 1 Haspin like kinase domain PP2C PF00481.21 CDJ42119.1 - 6.9e-31 107.8 0.0 3.5e-30 105.5 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Ketoacyl-synt_C PF02801.22 CDJ42119.1 - 1.7 8.6 8.2 21 5.2 0.0 4.2 4 0 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain FAST_1 PF06743.15 CDJ42120.1 - 0.00059 19.7 1.2 0.27 11.2 1.4 3.7 3 0 0 3 3 3 2 FAST kinase-like protein, subdomain 1 RRM_1 PF00076.22 CDJ42122.1 - 7.3e-13 48.1 0.0 1.6e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1314 PF07013.11 CDJ42122.1 - 0.027 14.4 0.3 0.19 11.6 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1314) TFIIA PF03153.13 CDJ42123.1 - 6.5e-08 33.0 13.3 5.2e-07 30.0 12.9 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit BSP_II PF05432.11 CDJ42123.1 - 0.06 13.0 19.5 0.087 12.5 19.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SRP-alpha_N PF04086.13 CDJ42123.1 - 0.38 10.6 14.0 0.49 10.3 14.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal R3H-assoc PF13902.6 CDJ42124.1 - 0.025 14.9 14.0 0.015 15.6 7.6 3.4 2 1 0 2 2 2 0 R3H-associated N-terminal domain AP3D1 PF06375.11 CDJ42126.1 - 0.0012 19.1 19.7 0.0018 18.5 19.7 1.3 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 SR-25 PF10500.9 CDJ42126.1 - 0.009 15.6 22.7 0.012 15.2 22.7 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Vfa1 PF08432.10 CDJ42126.1 - 0.053 13.8 18.0 0.066 13.5 18.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 CDJ42126.1 - 0.19 11.9 3.0 0.2 11.8 3.0 1.1 1 0 0 1 1 1 0 DDHD domain CRA PF06589.11 CDJ42126.1 - 0.2 11.8 24.1 0.3 11.2 24.1 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Presenilin PF01080.17 CDJ42126.1 - 0.32 9.7 2.9 0.33 9.7 2.9 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ42126.1 - 0.41 10.7 1.2 0.4 10.7 1.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 CDJ42126.1 - 0.66 9.1 1.8 0.62 9.2 1.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FAM176 PF14851.6 CDJ42126.1 - 0.92 9.2 3.9 1.4 8.6 3.9 1.3 1 0 0 1 1 1 0 FAM176 family RNA_polI_A34 PF08208.11 CDJ42126.1 - 0.94 9.5 24.2 1.2 9.2 24.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Paramyxo_ncap PF00973.19 CDJ42126.1 - 1 8.2 7.5 1.1 8.1 7.5 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDC45 PF02724.14 CDJ42126.1 - 1.2 7.3 9.8 1.3 7.2 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein TMEM214 PF10151.9 CDJ42126.1 - 2 6.8 11.8 2.3 6.6 11.8 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Connexin PF00029.19 CDJ42126.1 - 2.7 7.7 9.3 3.4 7.4 9.3 1.2 1 0 0 1 1 1 0 Connexin Eapp_C PF10238.9 CDJ42126.1 - 2.8 8.0 8.9 4 7.5 8.9 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein PPL5 PF18168.1 CDJ42126.1 - 3.4 6.9 11.6 5 6.3 11.6 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Ureide_permease PF07168.11 CDJ42126.1 - 5.1 5.7 6.4 6.6 5.4 6.4 1.1 1 0 0 1 1 1 0 Ureide permease SR-25 PF10500.9 CDJ42127.1 - 0.0055 16.4 8.1 0.0077 15.9 8.1 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SOUL PF04832.12 CDJ42127.1 - 0.019 15.1 0.3 0.035 14.3 0.3 1.4 2 0 0 2 2 2 0 SOUL heme-binding protein DUF2681 PF10883.8 CDJ42127.1 - 0.04 14.3 3.1 0.061 13.7 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF2207 PF09972.9 CDJ42127.1 - 0.25 10.1 1.1 0.28 9.9 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PsbM PF05151.12 CDJ42130.1 - 0.073 12.9 0.8 0.13 12.1 0.8 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) DUF412 PF04217.13 CDJ42130.1 - 0.36 10.7 3.8 5.8 6.8 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF412 Sulfotransfer_3 PF13469.6 CDJ42131.1 - 0.025 15.0 0.0 0.062 13.7 0.0 1.6 1 1 0 1 1 1 0 Sulfotransferase family LapA_dom PF06305.11 CDJ42131.1 - 0.16 11.8 1.5 15 5.5 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MADF_DNA_bdg PF10545.9 CDJ42131.1 - 0.54 10.6 9.2 0.5 10.7 1.6 2.2 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like CEP63 PF17045.5 CDJ42131.1 - 1.8 8.4 10.0 0.9 9.4 7.9 1.6 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa SR-25 PF10500.9 CDJ42132.1 - 0.11 12.0 9.1 0.15 11.7 9.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM60A PF15396.6 CDJ42132.1 - 0.34 10.9 2.7 0.34 10.9 2.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A BAF1_ABF1 PF04684.13 CDJ42132.1 - 0.51 9.3 5.8 0.58 9.2 5.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FGF-BP1 PF06473.12 CDJ42132.1 - 6 6.6 10.0 7.5 6.3 10.0 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Neur_chan_memb PF02932.16 CDJ42132.1 - 7.1 6.6 5.1 8 6.4 5.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.12 CDJ42132.1 - 9.8 5.5 11.9 12 5.1 11.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Herpes_LMP1 PF05297.11 CDJ42133.1 - 5.7 6.0 5.5 0.81 8.8 1.0 1.9 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Peptidase_M24 PF00557.24 CDJ42134.1 - 7.7e-16 58.4 7.3 8.3e-11 42.0 0.2 3.1 2 1 1 3 3 3 3 Metallopeptidase family M24 MID_MedPIWI PF18296.1 CDJ42135.1 - 0.006 16.4 0.3 0.0065 16.3 0.3 1.2 1 0 0 1 1 1 1 MID domain of medPIWI Sec23_helical PF04815.15 CDJ42135.1 - 0.032 14.0 2.9 0.063 13.1 2.9 1.5 1 0 0 1 1 1 0 Sec23/Sec24 helical domain TFIIA PF03153.13 CDJ42135.1 - 0.34 10.9 4.2 0.45 10.5 4.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 CDJ42135.1 - 0.41 7.7 3.1 0.51 7.4 3.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCDC24 PF15669.5 CDJ42135.1 - 6 6.7 12.5 0.69 9.7 7.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Pkinase PF00069.25 CDJ42136.1 - 3.8e-22 78.9 0.0 3.5e-16 59.3 0.0 2.3 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ42136.1 - 5.6e-13 48.8 0.1 5.1e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DSHCT PF08148.12 CDJ42136.1 - 0.021 14.5 0.1 0.021 14.5 0.1 2.2 2 1 0 2 2 2 0 DSHCT (NUC185) domain Spt20 PF12090.8 CDJ42136.1 - 0.037 13.7 4.6 0.046 13.3 4.6 1.2 1 0 0 1 1 1 0 Spt20 family DUF3412 PF11892.8 CDJ42136.1 - 0.098 12.7 0.6 0.19 11.8 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3412) Kinase-like PF14531.6 CDJ42136.1 - 0.12 11.7 2.6 1.2 8.4 0.0 2.7 2 1 1 3 3 3 0 Kinase-like Activator_LAG-3 PF11498.8 CDJ42136.1 - 0.13 11.2 20.9 0.2 10.6 20.9 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Macoilin PF09726.9 CDJ42138.1 - 0.32 9.5 16.9 0.39 9.2 16.9 1.0 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CDJ42138.1 - 2.1 8.2 14.3 2.7 7.9 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.11 CDJ42138.1 - 3.7 5.7 12.1 4.3 5.5 12.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Menin PF05053.13 CDJ42138.1 - 6.2 5.1 9.4 7 4.9 9.4 1.0 1 0 0 1 1 1 0 Menin Neur_chan_memb PF02932.16 CDJ42138.1 - 6.4 6.8 9.1 7.9 6.5 9.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Miga PF10265.9 CDJ42138.1 - 7.3 5.4 11.4 8.4 5.2 11.4 1.0 1 0 0 1 1 1 0 Mitoguardin DUF702 PF05142.12 CDJ42139.1 - 0.0022 18.5 5.1 0.0022 18.5 5.1 5.9 4 2 1 5 5 5 1 Domain of unknown function (DUF702) DUF572 PF04502.13 CDJ42139.1 - 0.83 9.2 16.6 0.074 12.7 3.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) UcrQ PF02939.16 CDJ42140.1 - 0.0037 17.1 0.8 0.0054 16.6 0.8 1.2 1 0 0 1 1 1 1 UcrQ family zf-C3HC4_2 PF13923.6 CDJ42142.1 - 4.9e-08 32.7 13.1 7.6e-08 32.1 13.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ42142.1 - 4.3e-06 27.0 13.8 6.7e-06 26.3 13.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ42142.1 - 6.2e-06 26.0 12.8 9.2e-06 25.4 12.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ42142.1 - 7.6e-06 25.7 14.1 1.2e-05 25.1 14.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ42142.1 - 0.00059 19.8 11.5 0.0013 18.8 11.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ42142.1 - 0.0006 19.7 12.5 0.00094 19.1 12.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 CDJ42142.1 - 0.0053 16.6 7.8 0.01 15.7 7.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein RAWUL PF16207.5 CDJ42142.1 - 0.059 14.0 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-Nse PF11789.8 CDJ42142.1 - 0.061 13.1 8.3 0.13 12.1 8.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 CDJ42142.1 - 0.24 11.6 12.4 0.43 10.8 12.4 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CDJ42142.1 - 0.35 11.2 7.3 0.82 10.0 7.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CDJ42142.1 - 0.49 10.2 10.3 0.98 9.3 10.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 CDJ42142.1 - 0.69 10.0 4.2 1.3 9.1 4.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CDJ42142.1 - 1.2 9.1 13.5 19 5.2 13.9 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 CDJ42142.1 - 1.5 8.8 10.3 2.7 8.0 9.3 1.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GYD PF08734.11 CDJ42144.1 - 0.0062 16.5 2.7 1.9 8.5 0.2 2.2 2 0 0 2 2 2 2 GYD domain Ribosomal_60s PF00428.19 CDJ42144.1 - 0.022 15.3 13.0 0.42 11.2 2.7 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein PixA PF12306.8 CDJ42144.1 - 0.44 10.7 6.8 13 5.9 3.0 2.9 2 1 0 2 2 2 0 Inclusion body protein Microtub_bind PF13931.6 CDJ42144.1 - 0.46 10.9 13.1 0.045 14.1 6.8 1.9 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding DUF883 PF05957.13 CDJ42144.1 - 0.57 10.8 19.1 0.53 10.9 2.6 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) CsgE PF10627.9 CDJ42144.1 - 1.1 9.4 16.4 1.9 8.8 0.6 3.0 2 1 0 2 2 2 0 Curli assembly protein CsgE Adeno_PIX PF03955.14 CDJ42144.1 - 1.3 9.2 10.0 3.4 7.9 0.9 2.4 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF4179 PF13786.6 CDJ42144.1 - 3.8 8.1 10.0 0.69 10.4 1.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) EIIBC-GUT_N PF03612.14 CDJ42144.1 - 6.2 6.5 9.3 2.1 8.0 3.9 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Tir_receptor_C PF07489.11 CDJ42144.1 - 6.2 6.7 24.7 0.26 11.2 1.3 3.2 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) C-terminus Pro_isomerase PF00160.21 CDJ42145.1 - 3.4e-38 131.4 0.1 2.5e-37 128.6 0.0 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2722 PF10846.8 CDJ42145.1 - 2.5e-05 23.4 18.8 0.0091 15.0 1.9 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) zf-NOSIP PF15906.5 CDJ42145.1 - 0.00013 22.0 0.6 0.00033 20.7 0.6 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Spt20 PF12090.8 CDJ42145.1 - 0.00089 18.9 30.0 0.0019 17.9 8.7 2.4 2 0 0 2 2 2 2 Spt20 family U-box PF04564.15 CDJ42145.1 - 0.00097 19.3 0.1 0.0036 17.5 0.0 2.1 2 0 0 2 2 1 1 U-box domain DUF5470 PF17564.2 CDJ42145.1 - 0.0012 18.9 0.3 0.0028 17.8 0.3 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5470) Med15 PF09606.10 CDJ42145.1 - 0.0083 14.9 27.3 0.031 13.0 3.8 2.4 3 0 0 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.9 CDJ42145.1 - 0.12 12.6 18.7 2.1 8.6 0.2 3.4 3 1 0 3 3 3 0 Anti-sigma-K factor rskA NARP1 PF12569.8 CDJ42145.1 - 0.15 10.9 0.0 0.15 10.9 0.0 2.8 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 RAB3GAP2_N PF14655.6 CDJ42145.1 - 0.37 10.0 12.2 0.21 10.8 2.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3371 PF11851.8 CDJ42145.1 - 0.54 11.4 14.9 1.8 9.7 2.4 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF3371) DUF4834 PF16118.5 CDJ42145.1 - 0.75 10.8 14.7 0.42 11.6 1.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) AAA_23 PF13476.6 CDJ42145.1 - 1.1 9.7 16.2 0.16 12.5 0.2 3.1 3 0 0 3 3 3 0 AAA domain eIF-3_zeta PF05091.12 CDJ42145.1 - 2.3 7.1 9.7 0.92 8.4 0.9 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PIP5K PF01504.18 CDJ42145.1 - 2.3 7.4 6.8 1 8.5 4.2 1.6 1 1 1 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Pex14_N PF04695.13 CDJ42145.1 - 3.6 8.2 17.1 4 8.1 0.1 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UPF0560 PF10577.9 CDJ42145.1 - 4 5.8 13.6 3.7 5.9 0.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 Kazal_2 PF07648.15 CDJ42145.1 - 4.2 7.6 13.8 22 5.3 13.8 2.3 1 1 0 1 1 1 0 Kazal-type serine protease inhibitor domain DUF382 PF04037.13 CDJ42145.1 - 5.8 7.1 10.4 3.7 7.7 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF382) TMEM208_SND2 PF05620.11 CDJ42145.1 - 8.9 6.1 10.1 9.3 6.0 0.2 2.5 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Dynein_C PF18199.1 CDJ42146.1 - 7.8e-21 74.6 0.0 3e-20 72.7 0.0 1.7 1 1 0 1 1 1 1 Dynein heavy chain C-terminal domain DUF4797 PF16051.5 CDJ42146.1 - 0.45 10.5 3.0 2.4 8.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4797) NolX PF05819.11 CDJ42146.1 - 0.51 9.6 8.7 0.62 9.3 8.7 1.0 1 0 0 1 1 1 0 NolX protein Spt20 PF12090.8 CDJ42147.1 - 0.0022 17.6 8.0 0.0025 17.5 8.0 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ42147.1 - 0.057 13.4 7.8 0.06 13.3 7.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Not1 PF04054.15 CDJ42148.1 - 3e-108 362.0 0.1 1.1e-107 360.1 0.0 2.0 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 RskA PF10099.9 CDJ42148.1 - 1.3e-05 25.5 0.7 1.3e-05 25.5 0.7 7.2 2 2 2 4 4 4 1 Anti-sigma-K factor rskA Pex14_N PF04695.13 CDJ42148.1 - 0.0062 17.2 2.5 0.0062 17.2 2.5 4.3 5 1 1 6 6 6 1 Peroxisomal membrane anchor protein (Pex14p) conserved region B56 PF01603.20 CDJ42148.1 - 2.5 7.0 10.8 0.16 10.9 2.9 2.1 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) Myosin_head PF00063.21 CDJ42149.1 - 6.3e-95 318.8 0.3 6.3e-76 256.0 0.0 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.6 CDJ42149.1 - 0.018 15.3 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CDJ42149.1 - 0.13 11.3 0.1 0.22 10.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 CDJ42149.1 - 0.13 12.6 5.7 0.086 13.2 2.8 2.2 2 1 0 2 2 2 0 AAA ATPase domain TFIIA PF03153.13 CDJ42149.1 - 0.95 9.4 6.6 0.84 9.6 5.8 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit K_channel_TID PF07941.11 CDJ42149.1 - 3.9 8.0 20.8 0.21 12.1 9.3 3.1 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain DUF3138 PF11336.8 CDJ42149.1 - 6.1 5.3 12.3 0.97 8.0 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) HRDC PF00570.23 CDJ42150.1 - 0.004 17.1 0.4 0.0075 16.2 0.4 1.4 1 0 0 1 1 1 1 HRDC domain RRM_1 PF00076.22 CDJ42151.1 - 2.4e-21 75.3 0.0 8e-10 38.4 0.0 4.2 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2722 PF10846.8 CDJ42151.1 - 0.0002 20.5 12.9 0.0005 19.2 1.9 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF2722) RRM_5 PF13893.6 CDJ42151.1 - 0.0033 17.0 0.0 0.66 9.6 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 CDJ42151.1 - 0.014 15.4 0.0 0.014 15.4 0.0 4.6 4 2 0 4 4 4 0 Smg-4/UPF3 family RRM_occluded PF16842.5 CDJ42151.1 - 0.03 14.2 0.1 0.3 11.0 0.0 2.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif Spt20 PF12090.8 CDJ42151.1 - 0.33 10.5 61.0 0.2 11.2 10.1 3.3 3 0 0 3 3 3 0 Spt20 family DUF4770 PF15994.5 CDJ42151.1 - 8.2 6.6 29.2 6.9 6.9 7.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) LRR_4 PF12799.7 CDJ42152.1 - 1.7e-10 41.0 12.1 0.00063 20.1 1.1 5.0 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ42152.1 - 1.9e-10 40.4 4.1 0.0065 16.2 0.2 5.2 4 1 1 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 CDJ42152.1 - 1.1e-05 25.0 1.5 6 7.2 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich repeat Spt20 PF12090.8 CDJ42152.1 - 0.0011 18.6 49.6 0.019 14.6 11.2 2.4 2 0 0 2 2 2 2 Spt20 family EOS1 PF12326.8 CDJ42152.1 - 0.0021 18.0 1.9 2.2 8.2 2.3 2.3 2 0 0 2 2 2 0 N-glycosylation protein FHIPEP PF00771.20 CDJ42152.1 - 0.004 15.7 9.6 0.015 13.8 0.2 2.3 2 0 0 2 2 2 1 FHIPEP family LRR_9 PF14580.6 CDJ42152.1 - 0.0079 15.7 7.9 0.17 11.4 0.3 3.5 3 1 1 4 4 3 1 Leucine-rich repeat Plasmodium_Vir PF05795.11 CDJ42152.1 - 0.0091 15.5 7.4 0.092 12.2 3.4 2.2 2 0 0 2 2 2 1 Plasmodium vivax Vir protein DUF4820 PF16091.5 CDJ42152.1 - 0.012 15.0 13.8 0.1 12.0 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Mus7 PF09462.10 CDJ42152.1 - 0.015 14.2 10.4 0.21 10.4 0.6 2.1 2 0 0 2 2 2 0 Mus7/MMS22 family MecA PF05389.12 CDJ42152.1 - 0.03 13.9 0.1 0.03 13.9 0.1 2.5 2 1 0 2 2 1 0 Negative regulator of genetic competence (MecA) Neur_chan_memb PF02932.16 CDJ42152.1 - 0.031 14.4 9.3 0.89 9.6 5.5 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Gti1_Pac2 PF09729.9 CDJ42152.1 - 0.041 14.0 11.3 3.4 7.7 8.0 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family DUF2722 PF10846.8 CDJ42152.1 - 0.042 12.8 41.4 0.012 14.6 9.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Eapp_C PF10238.9 CDJ42152.1 - 0.045 13.8 20.4 0.64 10.1 9.0 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein FAM176 PF14851.6 CDJ42152.1 - 0.06 13.0 14.9 0.15 11.7 4.1 2.3 2 0 0 2 2 2 0 FAM176 family DUF3381 PF11861.8 CDJ42152.1 - 0.082 12.7 23.5 0.018 14.9 5.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) EPL1 PF10513.9 CDJ42152.1 - 0.091 13.1 21.5 0.053 13.9 5.6 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Methyltransf_23 PF13489.6 CDJ42152.1 - 0.11 12.3 2.3 2.3 8.0 0.1 2.4 2 0 0 2 2 2 0 Methyltransferase domain PA26 PF04636.13 CDJ42152.1 - 0.11 11.4 9.2 3 6.7 0.1 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) RXT2_N PF08595.11 CDJ42152.1 - 0.13 12.3 11.2 0.96 9.5 0.1 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal ORC_WH_C PF18137.1 CDJ42152.1 - 0.15 12.1 20.3 0.2 11.7 0.1 2.7 2 1 0 2 2 2 0 Origin recognition complex winged helix C-terminal LRR_1 PF00560.33 CDJ42152.1 - 0.17 12.5 10.7 83 4.4 0.1 5.7 6 0 0 6 6 5 0 Leucine Rich Repeat Peroxin-13_N PF04088.13 CDJ42152.1 - 0.23 11.7 9.3 5.3 7.3 0.1 2.5 2 0 0 2 2 2 0 Peroxin 13, N-terminal region RskA PF10099.9 CDJ42152.1 - 0.23 11.7 67.6 1.6 9.0 15.1 4.4 1 1 2 3 3 1 0 Anti-sigma-K factor rskA RNase_H2_suC PF08615.11 CDJ42152.1 - 0.24 11.6 10.4 0.79 9.9 0.1 2.5 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF4834 PF16118.5 CDJ42152.1 - 0.25 12.3 24.9 1.9 9.5 4.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SpoIIP PF07454.11 CDJ42152.1 - 0.25 10.8 21.8 0.81 9.1 9.4 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 CDJ42152.1 - 0.25 10.3 16.1 0.71 8.8 8.0 2.2 2 0 0 2 2 2 0 Solute carrier family 12 DUF5523 PF17661.1 CDJ42152.1 - 0.42 10.3 21.4 0.19 11.4 1.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Folate_carrier PF01770.18 CDJ42152.1 - 0.48 9.1 9.9 0.5 9.0 0.2 2.1 2 0 0 2 2 2 0 Reduced folate carrier DUF1980 PF09323.10 CDJ42152.1 - 0.52 10.2 10.2 8.1 6.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) zf-C2H2_3rep PF18868.1 CDJ42152.1 - 0.53 11.0 10.7 0.97 10.1 5.0 2.4 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Dpy19 PF10034.9 CDJ42152.1 - 0.59 8.3 3.6 4.2 5.4 0.7 2.0 2 0 0 2 2 2 0 Q-cell neuroblast polarisation MMR1 PF08505.10 CDJ42152.1 - 0.68 10.2 26.0 0.074 13.3 8.6 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein AP-5_subunit_s1 PF15001.6 CDJ42152.1 - 0.73 9.8 16.2 1.6 8.6 5.8 2.5 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 AAA_23 PF13476.6 CDJ42152.1 - 0.9 10.0 22.0 0.19 12.2 2.4 2.3 2 0 0 2 2 2 0 AAA domain Baculo_PP31 PF05311.11 CDJ42152.1 - 0.96 8.9 14.0 6.5 6.2 9.2 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Afi1 PF07792.12 CDJ42152.1 - 1 9.9 21.5 0.71 10.4 2.7 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Rad54_N PF08658.10 CDJ42152.1 - 1 9.5 12.3 2.6 8.2 1.6 2.4 2 0 0 2 2 2 0 Rad54 N terminal PIP5K PF01504.18 CDJ42152.1 - 1.1 8.4 14.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase TERB2 PF15101.6 CDJ42152.1 - 1.1 9.2 30.0 0.39 10.7 4.5 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Peptidase_S49_N PF08496.10 CDJ42152.1 - 1.2 9.2 19.7 1 9.4 7.2 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Radial_spoke PF04712.12 CDJ42152.1 - 1.2 8.0 13.9 2.4 7.0 1.7 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein NinG PF05766.12 CDJ42152.1 - 1.3 9.0 15.1 4.9 7.0 0.3 2.3 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein NPR3 PF03666.13 CDJ42152.1 - 1.4 7.6 16.6 3.8 6.2 0.5 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 MH2 PF03166.14 CDJ42152.1 - 1.5 9.1 7.4 4.6 7.4 0.6 2.3 2 0 0 2 2 2 0 MH2 domain GPCR_chapero_1 PF11904.8 CDJ42152.1 - 1.5 8.2 10.4 3.7 6.9 3.7 2.3 2 0 0 2 2 2 0 GPCR-chaperone Mem_trans PF03547.18 CDJ42152.1 - 1.6 7.0 6.8 0.058 11.8 0.2 1.8 2 0 0 2 2 2 0 Membrane transport protein RAB3GAP2_C PF14656.6 CDJ42152.1 - 1.8 6.7 15.1 0.18 10.0 2.1 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Smg8_Smg9 PF10220.9 CDJ42152.1 - 1.8 6.7 15.4 7.2 4.8 10.5 2.2 2 0 0 2 2 2 0 Smg8_Smg9 DUF2052 PF09747.9 CDJ42152.1 - 1.9 8.6 27.0 0.65 10.1 2.4 2.5 3 0 0 3 3 2 0 Coiled-coil domain containing protein (DUF2052) DUF2151 PF10221.9 CDJ42152.1 - 2 6.9 9.9 0.92 8.0 4.0 2.0 2 0 0 2 2 2 0 Cell cycle and development regulator Band_3_cyto PF07565.13 CDJ42152.1 - 2.4 7.9 19.7 2.7 7.7 0.8 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Pinin_SDK_memA PF04696.13 CDJ42152.1 - 2.4 8.2 36.6 1.4 8.9 16.0 2.3 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region OATP PF03137.20 CDJ42152.1 - 2.6 6.2 8.9 2.6 6.2 0.1 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family NARP1 PF12569.8 CDJ42152.1 - 2.8 6.8 22.3 2.4 7.0 12.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Dynamin_N PF00350.23 CDJ42152.1 - 3.2 7.8 9.9 7.9 6.5 3.6 2.2 2 0 0 2 2 2 0 Dynamin family dsRBD2 PF17842.1 CDJ42152.1 - 3.6 7.8 12.0 6 7.1 0.8 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 DAG_kinase_N PF14513.6 CDJ42152.1 - 4.6 7.4 19.7 5.1 7.3 1.2 2.5 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus XAP5 PF04921.14 CDJ42152.1 - 4.6 7.0 18.5 3 7.6 0.6 2.4 2 0 0 2 2 2 0 XAP5, circadian clock regulator MAT1 PF06391.13 CDJ42152.1 - 4.7 7.0 27.9 0.81 9.5 5.9 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DNA_pol_delta_4 PF04081.13 CDJ42152.1 - 4.9 7.5 22.1 0.75 10.1 8.7 2.5 2 0 0 2 2 2 0 DNA polymerase delta, subunit 4 Sec62 PF03839.16 CDJ42152.1 - 5 6.6 17.7 4.3 6.8 8.7 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 Saw1 PF11561.8 CDJ42152.1 - 5.6 6.4 10.9 2.3 7.7 0.3 2.2 2 0 0 2 2 2 0 Single strand annealing-weakened 1 Zip PF02535.22 CDJ42152.1 - 5.7 6.1 8.7 15 4.6 0.2 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter PPL5 PF18168.1 CDJ42152.1 - 5.8 6.1 17.3 7.2 5.8 9.6 2.2 2 0 0 2 2 2 0 Prim-pol family 5 Serinc PF03348.15 CDJ42152.1 - 6.2 5.6 11.5 9.9 5.0 0.4 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF4770 PF15994.5 CDJ42152.1 - 6.7 6.9 21.0 3.2 8.0 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) CLN3 PF02487.17 CDJ42152.1 - 7 5.6 17.3 1.7 7.6 0.2 2.2 2 0 0 2 2 2 0 CLN3 protein SID-1_RNA_chan PF13965.6 CDJ42152.1 - 7.1 4.9 7.6 5.5 5.3 2.7 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 ALMT PF11744.8 CDJ42152.1 - 7.8 5.2 17.5 6.8 5.4 10.0 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter Pex26 PF07163.12 CDJ42152.1 - 8.1 5.7 20.5 1.8 7.8 2.9 2.5 2 0 0 2 2 2 0 Pex26 protein DUF2828 PF11443.8 CDJ42152.1 - 8.1 4.4 18.9 2.8 5.9 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Raftlin PF15250.6 CDJ42152.1 - 8.1 5.1 19.8 2.5 6.7 0.0 2.4 3 0 0 3 3 2 0 Raftlin TRAP_alpha PF03896.16 CDJ42152.1 - 8.3 5.5 14.5 3.8 6.6 1.0 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit eIF-3_zeta PF05091.12 CDJ42152.1 - 8.4 5.2 27.8 0.69 8.8 10.6 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MPM1 PF17234.2 CDJ42152.1 - 8.8 6.6 24.9 3.9 7.7 10.5 2.3 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 ABC2_membrane_2 PF12679.7 CDJ42152.1 - 8.9 5.5 11.1 3 7.0 4.0 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein Pet20 PF08692.10 CDJ42152.1 - 9.3 7.0 9.5 27 5.5 0.3 2.3 2 0 0 2 2 2 0 Mitochondrial protein Pet20 DUF913 PF06025.12 CDJ42152.1 - 9.8 5.0 22.1 1.6 7.6 0.1 2.5 2 1 1 3 3 3 0 Domain of Unknown Function (DUF913) DUF5320 PF17253.2 CDJ42153.1 - 3.7e-05 24.7 0.4 0.24 12.5 0.1 2.8 2 0 0 2 2 2 2 Family of unknown function (DUF5320) Glutaredoxin2_C PF04399.13 CDJ42153.1 - 0.018 14.8 0.4 9.7 6.0 0.1 2.8 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain C6 PF01681.17 CDJ42153.1 - 0.032 14.7 1.6 11 6.7 0.1 2.8 2 0 0 2 2 2 0 C6 domain Filament_head PF04732.14 CDJ42153.1 - 0.058 14.3 34.3 13 6.7 0.0 4.9 5 0 0 5 5 5 0 Intermediate filament head (DNA binding) region Allexi_40kDa PF05549.11 CDJ42153.1 - 0.06 12.8 4.7 2.8 7.4 0.3 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein CDC14 PF08045.11 CDJ42153.1 - 0.42 9.7 3.7 11 5.0 0.2 2.7 2 0 0 2 2 2 0 Cell division control protein 14, SIN component Nitro_FeMo-Co PF02579.17 CDJ42153.1 - 0.59 10.5 11.9 5.8 7.3 2.3 2.9 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor HMMR_N PF15905.5 CDJ42153.1 - 0.64 9.4 5.9 6.8 6.1 0.6 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal HR1 PF02185.16 CDJ42153.1 - 1.2 9.3 7.5 15 5.8 0.9 2.9 2 0 0 2 2 2 0 Hr1 repeat Fmp27_WPPW PF10359.9 CDJ42153.1 - 2.1 7.1 6.6 8.2 5.2 0.7 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Corona_nucleoca PF00937.18 CDJ42153.1 - 2.6 7.0 14.3 2.8 6.9 3.1 2.3 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein tRNA_NucTran2_2 PF13735.6 CDJ42153.1 - 2.8 7.9 6.8 17 5.3 0.7 2.6 2 2 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative UPF0565 PF10561.9 CDJ42153.1 - 2.8 7.0 9.0 6.9 5.8 1.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 End3 PF12761.7 CDJ42153.1 - 2.8 8.0 12.8 3 8.0 0.1 3.4 3 1 1 4 4 4 0 Actin cytoskeleton-regulatory complex protein END3 DUF1635 PF07795.11 CDJ42153.1 - 4.9 6.9 10.2 13 5.6 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) AAA_11 PF13086.6 CDJ42155.1 - 1.4e-51 175.8 3.5 1.5e-37 129.8 1.6 9.0 8 2 0 8 8 8 3 AAA domain AAA_12 PF13087.6 CDJ42155.1 - 1.2e-46 158.9 0.0 1.6e-45 155.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDJ42155.1 - 2e-06 28.2 3.5 4e-05 24.0 0.1 3.7 3 0 0 3 3 3 1 AAA domain DUF1980 PF09323.10 CDJ42155.1 - 0.0017 18.3 0.9 0.0017 18.3 0.9 5.2 9 0 0 9 9 9 1 Domain of unknown function (DUF1980) AAA_22 PF13401.6 CDJ42155.1 - 0.061 13.6 0.1 0.061 13.6 0.1 4.0 4 1 0 4 4 4 0 AAA domain AAA PF00004.29 CDJ42155.1 - 0.46 10.9 2.0 0.79 10.2 0.1 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) His_Phos_1 PF00300.22 CDJ42156.1 - 2e-06 27.6 9.4 0.029 14.1 0.1 4.5 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 1) DUF2195 PF09961.9 CDJ42156.1 - 0.2 11.6 2.0 0.53 10.2 0.3 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2195) Pro_isomerase PF00160.21 CDJ42157.1 - 3.5e-34 118.4 0.0 7.5e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SYF2 PF08231.12 CDJ42157.1 - 6e-29 101.5 2.8 6e-29 101.5 2.8 4.0 2 2 0 3 3 3 1 SYF2 splicing factor Ribosomal_L3 PF00297.22 CDJ42158.1 - 2e-12 46.8 3.6 7.4e-10 38.3 1.4 3.0 2 1 1 3 3 3 3 Ribosomal protein L3 ubiquitin PF00240.23 CDJ42159.1 - 4.3e-07 29.6 0.0 1e-06 28.4 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ42159.1 - 0.00062 19.5 0.1 0.0036 17.1 0.0 2.2 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like DUF237 PF03072.14 CDJ42159.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF237) ParD_antitoxin PF03693.14 CDJ42159.1 - 0.18 12.2 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH WD40 PF00400.32 CDJ42160.1 - 0.0015 19.3 2.0 0.072 14.0 0.0 2.8 2 1 0 2 2 2 1 WD domain, G-beta repeat BBS2_N PF14781.6 CDJ42160.1 - 0.014 15.3 0.2 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal ANAPC4_WD40 PF12894.7 CDJ42160.1 - 0.02 15.2 0.0 0.31 11.4 0.0 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_60s PF00428.19 CDJ42160.1 - 0.6 10.7 17.4 0.14 12.8 4.5 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ42160.1 - 0.64 10.0 7.9 0.83 9.6 7.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YajC PF02699.15 CDJ42160.1 - 0.66 9.9 4.7 1.7 8.6 0.4 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit PepSY_TM PF03929.16 CDJ42160.1 - 1.1 8.9 12.4 0.36 10.4 2.6 1.9 1 1 1 2 2 2 0 PepSY-associated TM region TFIIIC_delta PF12657.7 CDJ42160.1 - 1.7 8.5 5.1 12 5.7 4.1 2.6 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term Alk_phosphatase PF00245.20 CDJ42161.1 - 0.017 14.1 1.2 0.021 13.8 1.2 1.1 1 0 0 1 1 1 0 Alkaline phosphatase Nucleos_tra2_C PF07662.13 CDJ42161.1 - 0.061 13.2 1.3 0.072 12.9 1.3 1.1 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus DUF4357 PF14267.6 CDJ42161.1 - 0.077 13.0 3.2 0.084 12.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) Spt20 PF12090.8 CDJ42161.1 - 0.12 12.0 3.1 0.13 11.9 3.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF4366 PF14283.6 CDJ42161.1 - 0.17 11.9 0.5 0.21 11.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PepSY_TM PF03929.16 CDJ42161.1 - 0.66 9.6 3.2 0.84 9.2 3.2 1.1 1 0 0 1 1 1 0 PepSY-associated TM region DUF4335 PF14233.6 CDJ42161.1 - 1.2 9.0 5.6 0.71 9.8 2.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4335) Robl_LC7 PF03259.17 CDJ42161.1 - 1.8 8.4 6.7 2.8 7.8 2.9 2.1 2 0 0 2 2 2 0 Roadblock/LC7 domain SUIM_assoc PF16619.5 CDJ42161.1 - 3 8.0 11.4 4.4 7.5 11.4 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 ISP1_C PF18161.1 CDJ42163.1 - 2.6e-13 49.9 0.0 3.3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ISP1 C-terminal ISP3_C PF18045.1 CDJ42163.1 - 3.4e-13 49.4 0.0 4.4e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 ISP3 C-terminal CDRT4 PF15213.6 CDJ42165.1 - 0.022 15.4 0.2 0.022 15.4 0.2 3.0 2 1 1 3 3 3 0 CMT1A duplicated region transcript 4 protein DUF4006 PF13179.6 CDJ42166.1 - 0.16 11.9 0.1 0.64 10.0 0.1 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF4006) EphA2_TM PF14575.6 CDJ42166.1 - 5.3 8.0 5.9 31 5.5 0.0 3.6 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain SpoU_sub_bind PF08032.12 CDJ42167.1 - 0.029 14.7 1.4 0.064 13.5 0.6 1.9 1 1 1 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DUF4618 PF15397.6 CDJ42167.1 - 0.035 13.5 12.0 0.043 13.2 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) BOP1NT PF08145.12 CDJ42167.1 - 0.048 13.6 1.9 0.059 13.3 1.9 1.1 1 0 0 1 1 1 0 BOP1NT (NUC169) domain USP8_interact PF08941.10 CDJ42167.1 - 0.87 9.4 7.7 0.25 11.1 4.6 1.6 1 1 1 2 2 2 0 USP8 interacting V_ATPase_I PF01496.19 CDJ42167.1 - 1.9 6.3 8.6 2.3 6.0 8.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ZapB PF06005.12 CDJ42167.1 - 3.2 8.2 19.5 1.1 9.8 7.4 2.8 1 1 1 2 2 2 0 Cell division protein ZapB Nucleoporin_N PF08801.11 CDJ42171.1 - 0.058 12.1 0.1 0.21 10.3 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like Snapin_Pallidin PF14712.6 CDJ42173.1 - 0.01 16.3 3.9 0.68 10.4 0.5 2.7 2 0 0 2 2 2 2 Snapin/Pallidin CdvA PF18822.1 CDJ42173.1 - 0.033 14.0 1.2 0.033 14.0 1.2 2.6 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Rx_N PF18052.1 CDJ42173.1 - 0.078 13.3 7.7 0.46 10.8 0.4 2.8 3 0 0 3 3 3 0 Rx N-terminal domain Tup_N PF08581.10 CDJ42173.1 - 0.094 13.0 4.3 0.49 10.7 0.1 3.0 3 0 0 3 3 3 0 Tup N-terminal DUF16 PF01519.16 CDJ42173.1 - 0.24 11.9 8.3 0.82 10.2 1.8 2.3 1 1 0 2 2 2 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 CDJ42173.1 - 2.9 7.9 9.5 0.81 9.7 0.6 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.9 CDJ42173.1 - 4.9 7.5 10.0 1.2 9.4 1.5 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein NPV_P10 PF05531.12 CDJ42173.1 - 5.7 7.5 7.1 16 6.1 1.3 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF883 PF05957.13 CDJ42173.1 - 8 7.1 13.2 0.39 11.3 0.5 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Phage_P2_GpU PF06995.11 CDJ42174.1 - 0.0046 16.6 0.1 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 Phage P2 GpU ATG16 PF08614.11 CDJ42174.1 - 0.73 10.0 14.3 3.7 7.7 6.2 2.3 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DHC_N1 PF08385.12 CDJ42176.1 - 2.4e-64 217.9 0.7 3.5e-64 217.4 0.7 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DUF4745 PF15923.5 CDJ42176.1 - 0.061 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) L27 PF02828.16 CDJ42176.1 - 0.12 12.2 0.6 0.67 9.8 0.1 2.5 2 0 0 2 2 2 0 L27 domain DHC_N2 PF08393.13 CDJ42177.1 - 2.2e-95 320.1 7.2 3.3e-95 319.5 7.2 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Rx_N PF18052.1 CDJ42177.1 - 0.013 15.8 0.7 0.46 10.8 0.1 3.1 2 0 0 2 2 2 0 Rx N-terminal domain Cag12 PF13117.6 CDJ42177.1 - 0.1 13.1 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Cag pathogenicity island protein Cag12 Plasmid_RAQPRD PF09686.10 CDJ42177.1 - 2.5 8.4 5.2 2.3 8.5 0.0 3.3 4 0 0 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) AAA_6 PF12774.7 CDJ42178.1 - 9.1e-62 208.9 0.3 1.2e-61 208.5 0.3 1.1 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 CDJ42178.1 - 0.0032 17.5 0.0 0.14 12.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ42178.1 - 0.0066 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ42178.1 - 0.095 13.0 0.8 0.2 11.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDJ42178.1 - 0.1 13.1 0.1 0.25 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDJ42178.1 - 0.15 11.8 0.4 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDJ42178.1 - 0.17 11.4 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_6 PF12774.7 CDJ42179.1 - 3.9e-65 220.0 0.0 4.5e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region T2SSE PF00437.20 CDJ42179.1 - 0.076 12.1 0.1 0.13 11.3 0.1 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_8 PF12780.7 CDJ42180.1 - 3.9e-83 278.8 0.0 2.3e-81 273.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDJ42180.1 - 2e-73 246.2 0.1 2e-73 246.2 0.1 2.6 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDJ42180.1 - 1.4e-60 203.9 0.0 5.1e-60 202.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region MT PF12777.7 CDJ42180.1 - 4.8e-48 163.9 9.4 6.6e-36 124.0 11.6 2.3 1 1 0 2 2 2 2 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CDJ42180.1 - 2.5e-25 89.0 0.0 6.7e-25 87.7 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDJ42180.1 - 6.9e-16 58.5 0.0 6.7e-07 29.4 0.0 3.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CDJ42180.1 - 1.6e-12 47.5 0.5 7.9e-12 45.3 0.1 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 CDJ42180.1 - 0.0026 18.2 0.0 0.04 14.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) VIT1 PF01988.19 CDJ42180.1 - 0.044 13.6 4.2 0.1 12.4 2.6 2.3 2 0 0 2 2 2 0 VIT family AAA_14 PF13173.6 CDJ42180.1 - 0.093 12.8 0.0 0.36 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDJ42180.1 - 0.11 12.8 0.0 1.1 9.5 0.0 2.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ42180.1 - 0.56 10.6 11.6 1.1 9.6 0.1 4.9 5 1 1 6 6 6 0 AAA ATPase domain Sec34 PF04136.15 CDJ42180.1 - 0.58 10.0 7.9 6.1 6.7 0.1 3.3 3 0 0 3 3 3 0 Sec34-like family Atg14 PF10186.9 CDJ42180.1 - 6.3 5.8 18.7 0.55 9.3 2.9 2.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Dynein_C PF18199.1 CDJ42181.1 - 6.9e-22 78.1 0.0 7.5e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Spc24 PF08286.11 CDJ42183.1 - 0.65 10.3 4.2 1.4 9.2 4.2 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 CENP-K PF11802.8 CDJ42184.1 - 0.011 15.4 2.3 0.011 15.4 2.3 2.0 2 0 0 2 2 2 0 Centromere-associated protein K DUF641 PF04859.12 CDJ42184.1 - 0.024 15.0 3.7 0.096 13.0 3.7 2.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF4795 PF16043.5 CDJ42184.1 - 7.9 6.0 10.1 4.3 6.9 2.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) Tctex-1 PF03645.13 CDJ42185.1 - 7.9e-20 71.0 0.0 9.3e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Lustrin_cystein PF14625.6 CDJ42187.1 - 0.0005 20.4 20.1 0.029 14.8 2.7 3.8 4 0 0 4 4 4 3 Lustrin, cysteine-rich repeated domain LEA_6 PF10714.9 CDJ42187.1 - 0.043 13.9 0.1 0.081 13.0 0.1 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 FOLN PF09289.10 CDJ42187.1 - 0.23 11.7 5.9 20 5.5 0.1 3.9 4 0 0 4 4 4 0 Follistatin/Osteonectin-like EGF domain Granulin PF00396.18 CDJ42187.1 - 0.6 10.5 17.8 1.5 9.2 1.0 4.2 4 0 0 4 4 4 0 Granulin CBM_19 PF03427.13 CDJ42187.1 - 1.5 8.9 15.6 3.2 7.8 0.1 4.5 4 1 1 5 5 5 0 Carbohydrate binding domain (family 19) Opy2 PF09463.10 CDJ42187.1 - 2.9 8.3 19.7 0.87 10.0 1.1 4.1 4 1 0 4 4 4 0 Opy2 protein Ephrin_rec_like PF07699.13 CDJ42187.1 - 7.1 6.5 19.0 1.4 8.8 0.3 4.4 4 1 1 5 5 5 0 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 CDJ42188.1 - 1.8e-06 27.6 17.1 1e-05 25.2 2.6 5.0 4 1 2 6 6 6 3 Putative ephrin-receptor like HrcA_DNA-bdg PF03444.15 CDJ42188.1 - 1.6 8.5 2.8 43 3.9 0.3 3.4 3 1 0 3 3 3 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Ephrin_rec_like PF07699.13 CDJ42189.1 - 0.0096 15.7 9.0 0.015 15.1 5.6 2.4 1 1 1 2 2 2 1 Putative ephrin-receptor like NCD3G PF07562.14 CDJ42189.1 - 0.012 15.6 4.9 1.6 8.7 0.6 2.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Furin-like_2 PF15913.5 CDJ42189.1 - 0.061 13.5 1.4 0.32 11.2 0.0 2.1 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich Dickkopf_N PF04706.12 CDJ42190.1 - 1.9 9.0 14.2 1.4e+02 3.1 9.9 3.3 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region NHL PF01436.21 CDJ42191.1 - 6.1e-13 48.1 0.3 0.021 14.9 0.0 4.0 4 0 0 4 4 4 3 NHL repeat SGL PF08450.12 CDJ42191.1 - 0.00021 21.0 0.3 0.088 12.4 0.0 3.0 2 1 2 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 CDJ42191.1 - 0.037 14.2 0.9 0.31 11.2 0.0 2.7 4 0 0 4 4 4 0 Arylesterase PQQ_3 PF13570.6 CDJ42191.1 - 0.34 11.4 3.5 0.5 10.9 0.2 3.0 4 0 0 4 4 4 0 PQQ-like domain Ephrin_rec_like PF07699.13 CDJ42192.1 - 1.2e-06 28.2 32.4 4e-05 23.3 8.9 4.4 2 2 1 4 4 4 3 Putative ephrin-receptor like NCD3G PF07562.14 CDJ42192.1 - 0.016 15.2 23.8 0.06 13.3 5.3 4.5 2 2 3 5 5 5 0 Nine Cysteines Domain of family 3 GPCR Lustrin_cystein PF14625.6 CDJ42192.1 - 0.043 14.2 39.4 0.14 12.5 5.0 6.2 2 2 4 6 6 6 0 Lustrin, cysteine-rich repeated domain Dickkopf_N PF04706.12 CDJ42192.1 - 0.65 10.5 25.8 21 5.7 2.3 5.3 3 2 1 4 4 4 0 Dickkopf N-terminal cysteine-rich region Lustrin_cystein PF14625.6 CDJ42193.1 - 0.025 14.9 36.8 0.96 9.9 1.8 5.9 3 2 2 5 5 5 0 Lustrin, cysteine-rich repeated domain CBM_14 PF01607.24 CDJ42193.1 - 0.84 9.8 14.2 0.24 11.6 1.7 3.5 2 1 1 3 3 3 0 Chitin binding Peritrophin-A domain Ephrin_rec_like PF07699.13 CDJ42193.1 - 1.6 8.6 42.0 1.2 9.0 7.2 5.2 2 2 2 4 4 4 0 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 CDJ42194.1 - 0.0077 16.0 3.9 0.0077 16.0 3.9 2.1 2 1 0 2 2 2 1 Putative ephrin-receptor like FAM165 PF14981.6 CDJ42196.1 - 0.063 13.1 0.2 0.063 13.1 0.2 4.4 5 0 0 5 5 5 0 FAM165 family Asp-B-Hydro_N PF05279.11 CDJ42196.1 - 0.069 13.2 21.1 0.11 12.6 21.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4936 PF16290.5 CDJ42196.1 - 0.65 10.7 7.6 0.21 12.3 3.3 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4936) Cytochrom_NNT PF03264.14 CDJ42196.1 - 0.96 9.1 8.5 0.73 9.5 6.1 2.0 1 1 1 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region MeaB PF03308.16 CDJ42196.1 - 1.1 8.2 5.5 1.8 7.5 5.3 1.5 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB BUD22 PF09073.10 CDJ42197.1 - 0.059 12.7 37.6 0.069 12.5 37.6 1.2 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 CDJ42197.1 - 0.11 12.3 31.5 0.16 11.9 31.5 1.5 1 0 0 1 1 1 0 SPX domain Nop14 PF04147.12 CDJ42197.1 - 1.9 6.6 27.1 2.4 6.3 27.1 1.3 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 CDJ42197.1 - 9.8 5.5 7.8 12 5.2 7.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) Pkinase PF00069.25 CDJ42198.1 - 1.1e-35 123.3 0.0 7.1e-35 120.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ42198.1 - 3.2e-19 69.2 0.0 1.4e-13 50.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CDJ42198.1 - 0.037 13.9 9.1 0.12 12.3 9.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family CDC27 PF09507.10 CDJ42199.1 - 3 7.1 10.0 3.1 7.1 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CPW_WPC PF09717.10 CDJ42200.1 - 0.0021 19.0 0.2 0.0048 17.9 0.2 1.6 1 0 0 1 1 1 1 Plasmodium falciparum domain of unknown function (CPW_WPC) Pol_alpha_B_N PF08418.10 CDJ42201.1 - 0.62 10.0 7.1 0.027 14.4 2.0 1.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Menin PF05053.13 CDJ42201.1 - 0.88 7.9 2.9 1.3 7.3 2.9 1.3 1 0 0 1 1 1 0 Menin DUF3704 PF12488.8 CDJ42201.1 - 1.5 8.6 6.7 3.7 7.3 6.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) Rrn6 PF10214.9 CDJ42201.1 - 2.6 6.4 17.8 2.9 6.3 17.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Presenilin PF01080.17 CDJ42201.1 - 4.7 5.9 4.6 5.8 5.6 4.6 1.3 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ42201.1 - 5 7.0 20.5 7 6.5 20.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ42202.1 - 0.051 13.2 12.9 0.059 13.0 12.9 1.2 1 0 0 1 1 1 0 Spt20 family DUF3292 PF11696.8 CDJ42202.1 - 0.12 10.8 10.4 0.13 10.6 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) TFIIA PF03153.13 CDJ42202.1 - 0.2 11.6 23.9 0.23 11.4 23.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ42202.1 - 1.1 7.7 11.4 1.3 7.5 11.4 1.0 1 0 0 1 1 1 0 Macoilin family Suf PF05843.14 CDJ42202.1 - 1.2 9.0 8.1 1.3 9.0 8.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RRM_1 PF00076.22 CDJ42204.1 - 2.7e-17 62.4 0.0 5.4e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 CDJ42204.1 - 1.1e-08 35.0 6.7 1.9e-08 34.2 6.7 1.4 1 0 0 1 1 1 1 WW domain RNA_bind PF08675.11 CDJ42204.1 - 0.0072 16.3 1.1 0.033 14.2 1.1 1.9 1 1 0 1 1 1 1 RNA binding domain DUF1866 PF08952.11 CDJ42204.1 - 0.014 15.2 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Nup35_RRM_2 PF14605.6 CDJ42204.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GREB1 PF15782.5 CDJ42205.1 - 1.8 5.6 42.5 2.9 4.9 42.5 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TMEM51 PF15345.6 CDJ42207.1 - 2e-08 34.4 0.1 2.4e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 Acyltransferase PF01553.21 CDJ42208.1 - 6.2e-14 51.8 0.0 1.6e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase tRNA-synt_1 PF00133.22 CDJ42209.1 - 2.8e-42 144.8 11.7 2.1e-17 62.6 0.0 7.0 5 2 1 7 7 7 6 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ42209.1 - 9.3e-08 32.2 0.0 0.00013 21.9 0.0 2.7 2 0 0 2 2 2 2 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ42209.1 - 5.3e-05 22.1 0.0 1.2 7.8 0.0 3.9 4 0 0 4 4 4 2 tRNA synthetases class I (M) Otopetrin PF03189.13 CDJ42209.1 - 0.18 10.6 0.4 2 7.1 0.0 2.9 3 1 0 3 3 3 0 Otopetrin SUIM_assoc PF16619.5 CDJ42209.1 - 6.8 6.8 0.0 5.9 7.0 4.0 11.7 12 1 0 12 12 12 0 Unstructured region C-term to UIM in Ataxin3 VioE PF18234.1 CDJ42210.1 - 0.086 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Violacein biosynthetic enzyme VioE NMD3 PF04981.13 CDJ42211.1 - 8.3e-54 182.6 6.7 1.2e-53 182.1 6.7 1.2 1 0 0 1 1 1 1 NMD3 family Tau95_N PF17682.1 CDJ42211.1 - 0.098 12.9 2.6 0.19 11.9 0.0 2.6 3 0 0 3 3 3 0 Tau95 Triple barrel domain CENP-R PF06729.12 CDJ42211.1 - 2.4 8.1 7.5 0.42 10.5 0.6 2.4 2 0 0 2 2 2 0 Kinetochore component, CENP-R Presenilin PF01080.17 CDJ42211.1 - 5.4 5.7 11.4 5.8 5.6 1.0 2.1 2 0 0 2 2 2 0 Presenilin Dynactin_p62 PF05502.13 CDJ42212.1 - 4.3e-11 42.3 16.2 1.6e-08 33.8 7.0 3.3 3 0 0 3 3 3 3 Dynactin p62 family DUF1455 PF07306.11 CDJ42212.1 - 0.0013 18.7 1.8 0.0043 17.0 1.8 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1455) DUF3006 PF11213.8 CDJ42213.1 - 2.1e-05 24.7 0.7 3.6e-05 23.9 0.0 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3006) CHS5_N PF16892.5 CDJ42213.1 - 3.8e-05 23.6 0.1 3.8e-05 23.6 0.1 1.5 2 0 0 2 2 2 1 Chitin biosynthesis protein CHS5 N-terminus Mic1 PF07035.12 CDJ42214.1 - 0.17 11.6 0.0 0.21 11.3 0.0 1.0 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like Bac_GDH PF05088.12 CDJ42215.1 - 4.1e-09 34.6 0.0 5.8e-09 34.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase SUIM_assoc PF16619.5 CDJ42215.1 - 9.3e-05 22.4 0.0 0.0011 18.9 0.0 2.6 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 ELFV_dehydrog_N PF02812.18 CDJ42215.1 - 0.00058 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SARAF PF06682.12 CDJ42215.1 - 0.81 9.3 4.4 3.2 7.3 1.2 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Glyco_hydro_9 PF00759.19 CDJ42215.1 - 5.3 6.4 9.5 9.6 5.5 1.8 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 DUF3824 PF12868.7 CDJ42216.1 - 0.05 14.3 10.6 0.05 14.3 10.6 2.1 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Connexin PF00029.19 CDJ42216.1 - 0.089 12.5 7.9 0.11 12.3 7.9 1.1 1 0 0 1 1 1 0 Connexin Spore_coat_CotO PF14153.6 CDJ42216.1 - 0.12 12.3 25.1 0.13 12.2 25.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Ureide_permease PF07168.11 CDJ42216.1 - 0.51 9.0 7.1 0.61 8.8 7.1 1.1 1 0 0 1 1 1 0 Ureide permease BAF1_ABF1 PF04684.13 CDJ42216.1 - 0.51 9.3 15.9 0.53 9.3 15.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Lin-8 PF03353.15 CDJ42216.1 - 0.52 9.8 16.8 0.53 9.8 16.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDK5_activator PF03261.15 CDJ42216.1 - 0.65 9.5 17.6 0.67 9.4 17.6 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein O-antigen_lig PF13425.6 CDJ42216.1 - 1.1 8.0 8.3 1.2 7.9 8.3 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4366 PF14283.6 CDJ42216.1 - 1.2 9.2 9.4 1.6 8.8 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Pex14_N PF04695.13 CDJ42216.1 - 1.2 9.7 19.9 1.7 9.3 19.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_S64 PF08192.11 CDJ42216.1 - 1.4 7.3 17.0 1.3 7.4 17.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 PMSI1 PF15322.6 CDJ42216.1 - 2.1 7.7 16.4 2.3 7.6 16.4 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative RskA PF10099.9 CDJ42216.1 - 3.3 8.0 25.0 0.15 12.3 8.8 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF1980 PF09323.10 CDJ42216.1 - 3.5 7.5 9.5 4.5 7.1 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Miga PF10265.9 CDJ42216.1 - 4 6.3 12.9 4.5 6.1 12.9 1.0 1 0 0 1 1 1 0 Mitoguardin HemX PF04375.14 CDJ42216.1 - 4.1 6.6 25.4 4.6 6.4 25.4 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Peptidase_S49_N PF08496.10 CDJ42216.1 - 5.8 7.0 14.7 8.2 6.5 14.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal UPF0560 PF10577.9 CDJ42216.1 - 6.9 5.0 17.4 8.1 4.8 17.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Lin-8 PF03353.15 CDJ42217.1 - 2.6 7.5 5.5 3.4 7.1 5.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ42217.1 - 5.6 5.7 7.2 6.9 5.4 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Secretin_N_2 PF07655.13 CDJ42217.1 - 5.8 7.5 15.4 2.9 8.5 0.4 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain tRNA-synt_1d PF00750.19 CDJ42218.1 - 8.2e-75 251.9 0.0 1.6e-74 250.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CDJ42218.1 - 9.2e-17 61.3 0.4 5.9e-13 49.0 0.0 2.7 2 0 0 2 2 2 2 DALR anticodon binding domain RLI PF04068.15 CDJ42218.1 - 5.8e-14 51.6 6.0 1.3e-13 50.5 6.0 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI ABC_tran PF00005.27 CDJ42218.1 - 1.4e-06 28.9 0.0 3.2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Fer4 PF00037.27 CDJ42218.1 - 2.2e-06 27.2 2.8 2.2e-06 27.2 2.8 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_6 PF12837.7 CDJ42218.1 - 6.7e-05 22.8 2.4 6.7e-05 22.8 2.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.7 CDJ42218.1 - 0.00076 20.0 6.2 0.0018 18.8 0.4 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Rad17 PF03215.15 CDJ42218.1 - 0.0013 18.7 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain Fer4_21 PF14697.6 CDJ42218.1 - 0.0039 17.3 11.7 0.0089 16.1 11.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 CDJ42218.1 - 0.0047 17.0 1.3 0.0047 17.0 1.3 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 CDJ42218.1 - 0.006 16.7 10.7 0.016 15.4 10.7 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_18 PF13238.6 CDJ42218.1 - 0.0075 16.8 0.0 0.021 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Fer4_10 PF13237.6 CDJ42218.1 - 0.011 15.9 1.6 0.011 15.9 1.6 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_21 PF13304.6 CDJ42218.1 - 0.027 14.3 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Fer4_16 PF13484.6 CDJ42218.1 - 0.04 14.9 1.0 0.04 14.9 1.0 2.8 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain IMUP PF15761.5 CDJ42218.1 - 0.056 14.1 7.5 0.15 12.7 7.5 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein AAA_29 PF13555.6 CDJ42218.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fer4_8 PF13183.6 CDJ42218.1 - 0.085 13.3 7.0 0.12 12.8 0.2 2.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_15 PF13175.6 CDJ42218.1 - 0.086 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Fer4_17 PF13534.6 CDJ42218.1 - 0.087 13.4 0.3 0.087 13.4 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Dehydrin PF00257.19 CDJ42218.1 - 0.46 11.0 4.3 0.15 12.6 1.1 1.7 2 0 0 2 2 2 0 Dehydrin Fer4_4 PF12800.7 CDJ42218.1 - 4.2 8.1 15.1 0.62 10.7 3.1 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Jun PF03957.13 CDJ42218.1 - 8.6 6.2 8.2 0.61 9.9 2.6 1.8 2 0 0 2 2 2 0 Jun-like transcription factor DUF1761 PF08570.10 CDJ42219.1 - 0.027 14.7 2.5 0.043 14.1 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) Cyt_bd_oxida_II PF02322.15 CDJ42219.1 - 0.64 9.3 7.4 0.91 8.8 7.4 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II ELFV_dehydrog PF00208.21 CDJ42220.1 - 5.2e-38 131.1 0.0 5e-24 85.4 0.0 2.2 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Jun PF03957.13 CDJ42220.1 - 0.035 14.0 0.1 0.05 13.5 0.1 1.2 1 0 0 1 1 1 0 Jun-like transcription factor Ribosomal_60s PF00428.19 CDJ42220.1 - 5 7.8 9.7 56 4.4 7.8 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-3CxxC_2 PF17180.4 CDJ42222.1 - 1.7e-11 44.6 6.1 1.7e-11 44.6 6.1 7.4 9 1 0 9 9 9 1 Zinc-binding domain F-box-like PF12937.7 CDJ42222.1 - 0.0042 17.0 0.3 0.012 15.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ42222.1 - 0.0074 16.1 0.1 0.0074 16.1 0.1 2.5 2 0 0 2 2 2 1 F-box domain ATP-sulfurylase PF01747.17 CDJ42223.1 - 4.8e-86 287.6 0.2 6.5e-86 287.2 0.2 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 CDJ42223.1 - 2.5e-51 173.7 0.2 9.5e-34 116.6 0.0 2.6 3 0 0 3 3 3 2 Adenylylsulphate kinase PUA_2 PF14306.6 CDJ42223.1 - 2.4e-31 108.5 0.0 2.1e-30 105.5 0.0 2.2 1 1 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 CDJ42223.1 - 8.5e-06 26.0 0.0 4.1e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 CDJ42223.1 - 0.00011 21.8 0.0 0.00029 20.4 0.0 1.7 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 CDJ42223.1 - 0.00075 19.8 0.0 0.0023 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ42223.1 - 0.0035 17.8 0.1 0.011 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 CDJ42223.1 - 0.0079 16.7 0.0 0.044 14.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CDJ42223.1 - 0.015 14.6 0.0 0.067 12.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin DpnI_C PF17726.1 CDJ42223.1 - 0.051 13.7 0.0 0.4 10.8 0.0 2.4 2 0 0 2 2 2 0 Dam-replacing HTH domain SUIM_assoc PF16619.5 CDJ42223.1 - 0.067 13.3 14.7 0.057 13.5 5.3 2.8 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MeaB PF03308.16 CDJ42223.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 CDJ42223.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CDJ42223.1 - 0.15 11.9 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3947 PF13135.6 CDJ42223.1 - 0.3 11.3 9.4 1.4 9.2 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) ACDC PF14733.6 CDJ42224.1 - 1.7e-22 79.5 0.8 3.8e-22 78.4 0.2 2.0 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ42224.1 - 3.6e-05 23.9 4.9 3.6e-05 23.9 4.9 2.2 2 0 0 2 2 2 1 AP2 domain ANAPC_CDC26 PF10471.9 CDJ42224.1 - 5.7 7.8 13.0 0.21 12.4 3.2 3.8 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Laminin_G_3 PF13385.6 CDJ42225.1 - 6.8e-08 32.8 0.0 1.7e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 CDJ42225.1 - 0.014 15.9 0.0 0.049 14.2 0.0 1.8 2 0 0 2 2 2 0 Laminin G domain DUF4811 PF16069.5 CDJ42226.1 - 0.018 14.9 0.0 0.02 14.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) Ribosomal_L32e PF01655.18 CDJ42227.1 - 0.072 13.5 0.5 0.15 12.5 0.5 1.5 1 0 0 1 1 1 0 Ribosomal protein L32 DnaJ PF00226.31 CDJ42229.1 - 4.3e-10 39.6 0.3 1.1e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain DUF4366 PF14283.6 CDJ42229.1 - 0.035 14.2 0.1 0.071 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TraC_F_IV PF11130.8 CDJ42229.1 - 0.047 13.3 3.5 0.057 13.0 2.5 1.4 1 1 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer OAD_gamma PF04277.13 CDJ42229.1 - 3.6 8.2 7.2 0.53 10.9 1.8 2.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain PITH PF06201.13 CDJ42231.1 - 2.6e-17 63.5 0.0 4.1e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 PITH domain DUF2890 PF11081.8 CDJ42231.1 - 1.5 8.9 5.4 2.4 8.3 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Cas_Csn2 PF09711.10 CDJ42232.1 - 0.4 10.3 6.1 0.068 12.8 1.5 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csn2) LETM1 PF07766.13 CDJ42233.1 - 7.1e-82 274.7 3.2 7.1e-82 274.7 3.2 2.5 2 0 0 2 2 2 1 LETM1-like protein HAD_2 PF13419.6 CDJ42233.1 - 0.053 13.6 0.6 0.23 11.5 0.2 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.25 CDJ42235.1 - 1.9e-21 76.7 0.0 4.8e-21 75.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ42235.1 - 4.1e-11 42.7 0.0 9.6e-11 41.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ42235.1 - 6e-10 38.8 0.0 1.7e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ42235.1 - 0.2 11.0 0.1 0.9 8.9 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSP90 PF00183.18 CDJ42236.1 - 8.3e-129 430.8 0.0 9.1e-85 285.5 0.1 3.4 2 1 0 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CDJ42236.1 - 2e-10 40.6 0.0 4.3e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ42236.1 - 9.6e-08 32.5 0.0 2.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_60s PF00428.19 CDJ42236.1 - 0.0096 16.5 0.5 0.0096 16.5 0.5 6.5 5 1 0 5 5 5 2 60s Acidic ribosomal protein Peptidase_U57 PF05582.12 CDJ42236.1 - 2.8 7.1 5.2 0.49 9.6 1.1 1.8 2 0 0 2 2 2 0 YabG peptidase U57 Med14 PF08638.11 CDJ42237.1 - 1.7e-08 34.1 7.6 3.4e-08 33.2 7.6 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 2_5_RNA_ligase2 PF13563.6 CDJ42237.1 - 1.4 8.9 14.8 0.31 11.0 1.4 3.9 3 0 0 3 3 3 0 2'-5' RNA ligase superfamily SR-25 PF10500.9 CDJ42237.1 - 5.3 6.6 22.9 0.04 13.5 8.3 2.8 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ42238.1 - 0.0041 16.7 10.0 0.0041 16.7 10.0 2.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ42238.1 - 0.021 13.8 29.0 0.025 13.5 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) DUF3682 PF12446.8 CDJ42238.1 - 0.072 13.6 0.1 0.072 13.6 0.1 4.9 4 2 0 4 4 4 0 Protein of unknown function (DUF3682) Roc PF08477.13 CDJ42238.1 - 0.21 11.8 1.0 0.62 10.3 1.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RskA PF10099.9 CDJ42238.1 - 0.22 11.8 0.0 0.22 11.8 0.0 4.4 2 2 1 4 4 4 0 Anti-sigma-K factor rskA SDA1 PF05285.12 CDJ42238.1 - 1.7 8.0 12.9 0.41 10.0 7.8 2.0 2 0 0 2 2 2 0 SDA1 BAF1_ABF1 PF04684.13 CDJ42238.1 - 2.2 7.3 11.3 0.31 10.0 7.0 1.6 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Neur_chan_memb PF02932.16 CDJ42238.1 - 3.3 7.7 10.7 5.6 6.9 8.1 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4434 PF14488.6 CDJ42238.1 - 3.5 7.6 12.2 5.5 7.0 4.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4434) V_ATPase_I PF01496.19 CDJ42238.1 - 5.4 4.8 11.8 1.1 7.1 6.2 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CAS_CSE1 PF03378.15 CDJ42239.1 - 1.5e-38 132.5 6.5 4.7e-38 130.8 6.5 1.9 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 CDJ42239.1 - 1.6e-26 93.0 0.1 9.9e-13 47.6 0.0 4.2 4 0 0 4 4 4 3 Cse1 SUIM_assoc PF16619.5 CDJ42240.1 - 0.034 14.2 11.0 0.23 11.5 7.4 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PAP2 PF01569.21 CDJ42241.1 - 3.1e-21 75.6 1.2 3.1e-21 75.6 1.2 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CDJ42241.1 - 0.018 15.6 0.2 0.018 15.6 0.2 2.6 3 0 0 3 3 3 0 PAP2 superfamily C-terminal DDE_Tnp_1_4 PF13701.6 CDJ42241.1 - 0.21 9.8 0.0 0.28 9.4 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 Band_7 PF01145.25 CDJ42242.1 - 1e-24 87.5 0.3 1.5e-24 87.0 0.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CDJ42242.1 - 0.00013 21.1 1.2 0.00017 20.8 1.2 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Band_7_1 PF13421.6 CDJ42242.1 - 0.064 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family WHAMM-JMY_N PF15920.5 CDJ42242.1 - 0.19 11.6 0.5 0.38 10.7 0.5 1.4 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated Neur_chan_memb PF02932.16 CDJ42243.1 - 0.00021 21.4 3.9 0.00028 21.0 3.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region LPG_synthase_TM PF03706.13 CDJ42243.1 - 0.25 10.9 0.4 0.3 10.6 0.4 1.0 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Peptidase_S49_N PF08496.10 CDJ42243.1 - 2.3 8.3 12.3 3.7 7.6 0.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4175 PF13779.6 CDJ42243.1 - 9.1 4.0 33.4 15 3.3 33.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4175) SET PF00856.28 CDJ42245.1 - 0.58 10.5 0.0 0.58 10.5 0.0 3.9 2 2 0 2 2 2 0 SET domain Hep_59 PF07052.11 CDJ42245.1 - 2 9.2 5.9 0.6 10.9 0.6 2.5 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Siah-Interact_N PF09032.11 CDJ42246.1 - 0.25 11.7 1.5 0.67 10.3 1.5 1.6 1 0 0 1 1 1 0 Siah interacting protein, N terminal Defensin_1 PF00323.19 CDJ42246.1 - 0.52 10.9 3.1 4.7 7.9 0.2 2.6 2 0 0 2 2 2 0 Mammalian defensin CREPT PF16566.5 CDJ42247.1 - 0.046 13.9 0.9 0.13 12.5 0.9 1.7 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour MCU PF04678.13 CDJ42247.1 - 7.8 6.6 6.2 12 5.9 1.0 2.5 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF2053 PF09767.9 CDJ42248.1 - 7.1e-26 91.3 4.8 9.4e-26 90.9 4.8 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) Ribosomal_L28 PF00830.19 CDJ42249.1 - 5.3e-08 32.9 0.8 1.6e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal L28 family V-SNARE_C PF12352.8 CDJ42251.1 - 2.1e-07 31.1 2.0 2.1e-07 31.1 2.0 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 CDJ42251.1 - 0.00098 17.2 5.6 0.0012 17.0 5.6 1.3 1 1 0 1 1 1 1 Prominin Synaptobrevin PF00957.21 CDJ42251.1 - 0.0095 15.7 0.7 0.026 14.3 0.2 2.0 2 0 0 2 2 2 1 Synaptobrevin Sec20 PF03908.13 CDJ42251.1 - 0.028 14.3 0.4 0.028 14.3 0.4 2.1 2 1 0 2 2 2 0 Sec20 PEP-utilisers_N PF05524.13 CDJ42251.1 - 0.041 14.1 0.3 0.041 14.1 0.3 2.5 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal Tox-URI2 PF15653.6 CDJ42251.1 - 0.061 13.6 1.1 0.43 10.9 0.1 2.3 1 1 0 2 2 2 0 URI fold toxin 2 Amidohydro_2 PF04909.14 CDJ42252.1 - 1.5e-10 41.3 0.0 3e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 CDJ42252.1 - 1.9e-08 34.1 0.1 8.8e-08 31.8 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family Asp PF00026.23 CDJ42254.1 - 4.3e-27 95.3 0.0 1.5e-13 50.9 0.0 4.0 1 1 2 3 3 3 3 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ42254.1 - 0.034 14.4 0.0 7.3 6.8 0.0 3.0 3 1 0 3 3 3 0 Xylanase inhibitor N-terminal Peptidase_M16 PF00675.20 CDJ42255.1 - 2.1e-43 147.9 0.5 1.3e-42 145.3 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 CDJ42255.1 - 2.2e-26 92.8 0.0 8.4e-26 90.9 0.0 1.9 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CDJ42255.1 - 8.8e-21 74.7 0.3 4.2e-08 33.4 0.0 3.9 4 0 0 4 4 4 3 Peptidase M16 inactive domain DUF974 PF06159.13 CDJ42256.1 - 3.8e-29 102.2 0.3 2.7e-24 86.3 0.7 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF974) Helicase_C PF00271.31 CDJ42257.1 - 1e-09 38.7 0.0 7.1e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ42257.1 - 2.8e-05 24.0 0.0 0.18 11.5 0.0 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase Complex1_LYR_2 PF13233.6 CDJ42257.1 - 0.027 15.2 0.7 0.073 13.8 0.7 1.7 1 0 0 1 1 1 0 Complex1_LYR-like ABC_tran PF00005.27 CDJ42258.1 - 2.1e-22 80.1 0.0 3.4e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 CDJ42258.1 - 2.3e-21 76.2 21.2 2.3e-21 76.2 21.2 1.4 2 0 0 2 2 1 1 ABC-2 type transporter AAA_25 PF13481.6 CDJ42258.1 - 1.6e-05 24.6 0.6 0.055 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CDJ42258.1 - 0.0027 18.2 0.0 0.0046 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CDJ42258.1 - 0.0028 18.2 0.0 0.0047 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ42258.1 - 0.003 18.0 0.0 0.006 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 CDJ42258.1 - 0.0046 16.8 0.0 0.049 13.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CDJ42258.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC2_membrane_3 PF12698.7 CDJ42258.1 - 0.017 14.3 23.3 0.0085 15.2 19.9 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein AAA_22 PF13401.6 CDJ42258.1 - 0.024 14.9 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CDJ42258.1 - 0.025 14.5 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 CDJ42258.1 - 0.066 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 CDJ42258.1 - 0.072 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 CDJ42258.1 - 0.073 12.8 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CDJ42258.1 - 0.088 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 CDJ42258.1 - 0.096 13.1 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CDJ42258.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 CDJ42258.1 - 0.16 11.9 0.6 0.32 10.9 0.1 1.8 2 0 0 2 2 1 0 NACHT domain AAA_24 PF13479.6 CDJ42258.1 - 0.17 11.6 0.0 0.45 10.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CDJ42258.1 - 0.19 11.5 0.0 0.5 10.1 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 CDJ42258.1 - 0.32 10.8 0.8 0.87 9.4 0.8 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TIP49 PF06068.13 CDJ42260.1 - 3.7e-158 526.3 0.1 4.6e-158 526.0 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CDJ42260.1 - 1.8e-17 63.2 0.3 4.8e-16 58.7 0.3 3.0 1 1 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CDJ42260.1 - 1.4e-12 48.2 0.0 1.9e-08 34.8 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ42260.1 - 5.2e-10 39.3 0.3 4.9e-07 29.6 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDJ42260.1 - 2.2e-06 28.0 0.1 0.028 14.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ42260.1 - 1.3e-05 25.7 0.0 0.0005 20.5 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CDJ42260.1 - 3.4e-05 23.9 0.1 0.0058 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CDJ42260.1 - 0.00015 22.2 0.1 0.063 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CDJ42260.1 - 0.00034 20.4 0.1 0.18 11.5 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CDJ42260.1 - 0.00088 18.7 0.2 0.036 13.5 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CDJ42260.1 - 0.001 19.6 0.0 0.0032 18.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain DnaB_C PF03796.15 CDJ42260.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CDJ42260.1 - 0.0028 17.4 0.1 0.0063 16.3 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 CDJ42260.1 - 0.0034 17.6 0.0 0.0076 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ42260.1 - 0.0039 17.2 0.1 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 CDJ42260.1 - 0.0044 16.6 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDJ42260.1 - 0.0049 16.9 0.0 3.9 7.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CDJ42260.1 - 0.0055 16.0 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 CDJ42260.1 - 0.0062 16.7 0.0 0.049 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CDJ42260.1 - 0.0065 16.0 0.5 0.04 13.4 0.0 2.3 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_11 PF13086.6 CDJ42260.1 - 0.0066 16.3 0.1 0.017 15.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CDJ42260.1 - 0.013 15.4 0.1 0.078 12.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 CDJ42260.1 - 0.017 14.4 0.1 0.044 13.1 0.1 1.7 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 CDJ42260.1 - 0.019 14.0 0.1 0.042 12.9 0.1 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 CDJ42260.1 - 0.024 15.1 0.0 0.053 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CDJ42260.1 - 0.031 14.2 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 CDJ42260.1 - 0.032 13.7 0.1 0.062 12.7 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 CDJ42260.1 - 0.035 14.5 0.0 0.083 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 CDJ42260.1 - 0.035 14.0 0.1 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 CDJ42260.1 - 0.037 13.7 0.8 0.5 10.1 0.3 2.6 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 CDJ42260.1 - 0.039 13.3 0.0 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 CDJ42260.1 - 0.043 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain PIF1 PF05970.14 CDJ42260.1 - 0.057 12.6 0.1 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_17 PF13207.6 CDJ42260.1 - 0.06 13.8 0.1 0.42 11.1 0.0 2.4 2 1 1 3 3 3 0 AAA domain T2SSE PF00437.20 CDJ42260.1 - 0.078 12.0 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein TniB PF05621.11 CDJ42260.1 - 0.11 11.9 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein IPT PF01745.16 CDJ42260.1 - 0.11 11.8 0.1 0.28 10.6 0.1 1.6 1 0 0 1 1 1 0 Isopentenyl transferase TsaE PF02367.17 CDJ42260.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SAS-6_N PF16531.5 CDJ42261.1 - 3.7e-28 97.9 3.2 6.2e-28 97.2 3.2 1.4 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal CSD PF00313.22 CDJ42261.1 - 0.088 12.7 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Rep_fac-A_C PF08646.10 CDJ42263.1 - 1.2e-26 93.3 0.1 2.4e-26 92.2 0.1 1.5 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CDJ42263.1 - 5.8e-15 55.0 0.0 1.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Replication protein A OB domain DZR PF12773.7 CDJ42263.1 - 0.011 15.8 0.9 0.026 14.5 0.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon tRNA_anti-codon PF01336.25 CDJ42263.1 - 0.013 15.4 0.1 26 4.9 0.0 3.4 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain PLATZ PF04640.14 CDJ42263.1 - 0.2 12.3 1.6 0.57 10.8 0.7 2.2 2 0 0 2 2 2 0 PLATZ transcription factor Importin_rep PF18773.1 CDJ42263.1 - 0.82 9.4 2.5 22 4.8 0.1 2.9 3 0 0 3 3 3 0 Importin 13 repeat Ribosomal_L21p PF00829.21 CDJ42264.1 - 1.1e-14 54.5 0.2 2.2e-14 53.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Tim17 PF02466.19 CDJ42265.1 - 1.4e-08 35.0 1.0 1.9e-08 34.7 0.3 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family OB_NTP_bind PF07717.16 CDJ42266.1 - 3e-13 49.9 0.3 1.2e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CDJ42266.1 - 1.3e-08 35.1 0.0 1.3e-08 35.1 0.0 3.2 3 1 0 3 3 3 1 Helicase associated domain (HA2) RED_C PF07807.11 CDJ42266.1 - 1 9.9 4.8 2.2 8.8 4.8 1.5 1 0 0 1 1 1 0 RED-like protein C-terminal region XhlA PF10779.9 CDJ42267.1 - 0.17 12.1 0.1 0.43 10.8 0.1 1.7 1 0 0 1 1 1 0 Haemolysin XhlA CRAL_TRIO PF00650.20 CDJ42268.1 - 1.4e-20 73.6 0.0 2.2e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Popeye PF04831.13 CDJ42269.1 - 3.3e-11 43.5 0.0 4.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 CDJ42269.1 - 0.00026 21.0 0.2 0.038 14.0 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain REV1_C PF16727.5 CDJ42270.1 - 0.049 14.0 1.0 0.12 12.8 1.0 1.6 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain Methyltr_RsmB-F PF01189.17 CDJ42271.1 - 3.7e-24 85.5 0.0 2e-13 50.4 0.0 3.3 3 0 0 3 3 3 3 16S rRNA methyltransferase RsmB/F Pantoate_transf PF02548.15 CDJ42273.1 - 2.8e-81 272.7 1.3 2.8e-81 272.7 1.3 1.7 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.11 CDJ42273.1 - 3.5e-11 43.4 0.2 8.5e-11 42.1 0.2 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CDJ42273.1 - 2e-09 37.3 0.0 2.1e-08 33.9 0.0 2.3 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA PEP_mutase PF13714.6 CDJ42273.1 - 0.0024 17.4 0.1 0.005 16.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase G6PD_C PF02781.16 CDJ42274.1 - 4.4e-107 357.6 0.0 4.9e-107 357.4 0.0 1.0 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain EF-hand_1 PF00036.32 CDJ42275.1 - 3.7e-18 63.6 0.1 2.3e-05 23.6 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CDJ42275.1 - 3.3e-15 56.3 0.0 1.4e-07 31.8 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ42275.1 - 1.7e-13 49.4 0.3 4.7e-05 22.7 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CDJ42275.1 - 1.1e-11 43.6 0.5 7.6e-05 22.3 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CDJ42275.1 - 3.1e-11 42.9 1.1 0.002 18.0 0.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair Dockerin_1 PF00404.18 CDJ42275.1 - 0.0089 16.2 3.6 0.27 11.5 0.0 3.3 3 1 0 3 3 3 1 Dockerin type I domain NolX PF05819.11 CDJ42275.1 - 0.018 14.4 0.5 0.025 13.9 0.5 1.2 1 0 0 1 1 1 0 NolX protein EF-hand_9 PF14658.6 CDJ42275.1 - 0.17 12.2 0.1 10 6.5 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain ApoL PF05461.11 CDJ42276.1 - 0.0097 15.3 0.5 0.014 14.7 0.5 1.3 1 0 0 1 1 1 1 Apolipoprotein L WXG100 PF06013.12 CDJ42276.1 - 0.036 14.3 0.2 0.099 12.9 0.2 1.7 1 0 0 1 1 1 0 Proteins of 100 residues with WXG KH_1 PF00013.29 CDJ42278.1 - 1.7e-22 79.0 0.0 3.9e-07 29.8 0.0 4.2 4 0 0 4 4 4 4 KH domain MOEP19 PF16005.5 CDJ42278.1 - 0.094 12.7 0.0 20 5.3 0.0 2.3 2 0 0 2 2 2 0 KH-like RNA-binding domain DUF775 PF05603.12 CDJ42279.1 - 0.0045 16.5 8.4 0.0075 15.8 8.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF775) SARAF PF06682.12 CDJ42279.1 - 0.0092 15.7 3.1 0.01 15.6 3.1 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF913 PF06025.12 CDJ42279.1 - 0.34 9.8 5.7 0.51 9.3 5.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Exonuc_VII_L PF02601.15 CDJ42279.1 - 0.38 10.3 18.0 0.52 9.8 18.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FHIPEP PF00771.20 CDJ42279.1 - 1.5 7.2 6.9 2.2 6.7 6.9 1.2 1 0 0 1 1 1 0 FHIPEP family DUF3616 PF12275.8 CDJ42279.1 - 1.7 8.0 6.9 2.6 7.4 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) eIF-3_zeta PF05091.12 CDJ42279.1 - 3.1 6.7 13.6 4.6 6.1 13.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FapA PF03961.13 CDJ42279.1 - 4.4 5.8 7.3 5.4 5.5 7.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Activator_LAG-3 PF11498.8 CDJ42279.1 - 7.1 5.5 39.9 10 5.0 39.9 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spore_coat_CotO PF14153.6 CDJ42279.1 - 9.8 6.0 21.8 1.2 9.1 17.8 1.6 2 0 0 2 2 2 0 Spore coat protein CotO AMPK1_CBM PF16561.5 CDJ42280.1 - 6e-31 106.5 2.2 9.3e-31 105.9 1.5 1.6 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase DUF1398 PF07166.11 CDJ42280.1 - 0.025 14.6 0.1 0.043 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) SR-25 PF10500.9 CDJ42281.1 - 0.0019 17.9 14.9 0.0019 17.9 14.9 2.9 2 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein HEAT_2 PF13646.6 CDJ42282.1 - 2.4e-12 47.1 33.1 9.2e-09 35.6 0.1 4.9 2 1 1 3 3 3 1 HEAT repeats HEAT_PBS PF03130.16 CDJ42282.1 - 6.4e-07 29.5 9.1 4.7e-06 26.8 0.4 6.4 6 0 0 6 6 6 3 PBS lyase HEAT-like repeat HEAT PF02985.22 CDJ42282.1 - 0.00033 20.6 8.7 0.25 11.7 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 CDJ42282.1 - 0.0036 17.3 3.6 2 8.4 1.0 3.3 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 CDJ42282.1 - 0.041 14.0 3.4 3 8.0 0.0 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TMEM173 PF15009.6 CDJ42282.1 - 0.31 10.2 1.9 0.47 9.6 1.9 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 DUF4820 PF16091.5 CDJ42282.1 - 6.1 6.1 7.7 0.43 9.9 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Peptidase_S49_N PF08496.10 CDJ42282.1 - 6.1 6.9 10.4 0.52 10.4 2.9 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Suf PF05843.14 CDJ42283.1 - 0.057 13.4 14.0 0.063 13.3 14.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SprA-related PF12118.8 CDJ42283.1 - 0.11 11.6 25.0 0.12 11.5 25.0 1.0 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.13 CDJ42283.1 - 0.86 9.5 24.5 0.95 9.4 24.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAJIN PF15077.6 CDJ42283.1 - 3.7 7.3 11.3 4.2 7.1 11.3 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein MAP70 PF07058.11 CDJ42283.1 - 7.2 5.2 14.0 7.9 5.1 14.0 1.0 1 0 0 1 1 1 0 Microtubule-associated protein 70 TFIIA PF03153.13 CDJ42284.1 - 2.8 7.8 18.1 3.1 7.7 18.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3450 PF11932.8 CDJ42284.1 - 3 7.1 13.0 3.8 6.7 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CCDC53 PF10152.9 CDJ42284.1 - 7.6 6.9 11.2 9 6.7 11.2 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Tic110 PF16940.5 CDJ42284.1 - 7.9 4.8 12.9 8 4.8 12.9 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter FAM199X PF15814.5 CDJ42284.1 - 9 5.2 6.7 11 5.0 6.7 1.0 1 0 0 1 1 1 0 Protein family FAM199X GcpE PF04551.14 CDJ42285.1 - 4.5e-127 423.9 0.0 1.2e-126 422.6 0.0 1.7 1 1 0 1 1 1 1 GcpE protein V_ATPase_I PF01496.19 CDJ42285.1 - 1.4 6.7 18.9 0.099 10.6 12.3 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DDHD PF02862.17 CDJ42285.1 - 1.9 8.6 14.0 0.95 9.6 6.1 3.1 4 0 0 4 4 4 0 DDHD domain Hist_deacetyl PF00850.19 CDJ42285.1 - 2.6 7.4 11.5 4 6.8 0.1 2.7 3 0 0 3 3 3 0 Histone deacetylase domain LRR_4 PF12799.7 CDJ42286.1 - 2.5e-05 24.5 0.4 2.5e-05 24.5 0.4 2.8 1 1 2 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ42286.1 - 0.00069 19.3 3.8 0.0028 17.4 3.8 1.9 1 1 1 2 2 2 1 Leucine rich repeat DUF1645 PF07816.11 CDJ42286.1 - 0.0017 19.0 2.2 0.0023 18.6 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) LRR_9 PF14580.6 CDJ42286.1 - 0.17 11.4 0.7 0.22 11.0 0.7 1.2 1 0 0 1 1 1 0 Leucine-rich repeat SR-25 PF10500.9 CDJ42286.1 - 8.5 5.9 16.1 13 5.3 16.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein McrBC PF10117.9 CDJ42288.1 - 0.099 11.8 0.4 0.15 11.1 0.4 1.2 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component DUF1488 PF07369.11 CDJ42288.1 - 0.63 10.1 5.6 3.7 7.6 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) Sec62 PF03839.16 CDJ42289.1 - 6.9e-12 45.3 13.3 6.9e-12 45.3 13.3 1.6 2 0 0 2 2 2 1 Translocation protein Sec62 Kinesin PF00225.23 CDJ42290.1 - 1.3e-88 297.2 0.5 1.1e-64 218.5 0.0 5.7 3 2 1 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ42290.1 - 2.1e-18 66.7 0.5 6.5e-16 58.6 0.3 3.7 4 1 0 4 4 4 2 Microtubule binding Ribosomal_S25 PF03297.15 CDJ42291.1 - 9.5e-36 122.1 0.3 1.1e-35 121.9 0.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Trp_halogenase PF04820.14 CDJ42291.1 - 0.071 11.9 0.0 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DEAD PF00270.29 CDJ42292.1 - 3.9e-30 104.9 1.1 1.1e-29 103.4 0.8 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ42292.1 - 1.3e-20 73.8 0.0 6.5e-20 71.5 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ42292.1 - 0.0012 19.1 0.4 0.011 16.0 0.4 2.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ42292.1 - 0.0015 18.6 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SIS PF01380.22 CDJ42292.1 - 0.0019 18.1 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 SIS domain DUF2075 PF09848.9 CDJ42292.1 - 0.085 12.1 0.0 3 7.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MRPL52 PF18699.1 CDJ42292.1 - 0.25 11.6 0.0 0.25 11.6 0.0 2.5 3 0 0 3 3 3 0 Mitoribosomal protein mL52 NACHT PF05729.12 CDJ42292.1 - 4 7.3 6.5 14 5.5 6.5 2.0 1 1 0 1 1 1 0 NACHT domain Phage_integrase PF00589.22 CDJ42293.1 - 2.8e-10 40.3 0.0 6.9e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Phage integrase family SAP PF02037.27 CDJ42293.1 - 1e-05 25.1 0.3 3e-05 23.6 0.3 1.8 1 0 0 1 1 1 1 SAP domain zinc_ribbon_2 PF13240.6 CDJ42293.1 - 2.1e-05 24.1 1.5 5e-05 22.9 1.5 1.7 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 CDJ42293.1 - 2.7e-05 24.1 0.6 8.2e-05 22.5 0.6 1.8 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 CDJ42293.1 - 0.00066 20.4 0.7 0.0014 19.3 0.7 1.6 1 0 0 1 1 1 1 zinc-ribbon family PLATZ PF04640.14 CDJ42293.1 - 0.0063 17.1 0.5 0.014 16.0 0.5 1.5 1 0 0 1 1 1 1 PLATZ transcription factor zf-ribbon_3 PF13248.6 CDJ42293.1 - 0.018 14.4 1.1 0.018 14.4 1.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 CDJ42293.1 - 0.062 13.3 0.4 0.14 12.2 0.4 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 CDJ42293.1 - 0.22 11.2 0.1 0.22 11.2 0.1 2.8 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain UQ_con PF00179.26 CDJ42295.1 - 1.2e-23 83.3 0.0 2.1e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CCDC106 PF15794.5 CDJ42295.1 - 5.5 6.6 7.8 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 NPR1_interact PF15699.5 CDJ42298.1 - 7 7.3 13.9 5.1 7.8 0.1 3.7 4 0 0 4 4 4 0 NPR1 interacting Peptidase_M3 PF01432.20 CDJ42299.1 - 4.4e-12 46.0 1.1 5.6e-12 45.7 1.1 1.3 1 1 0 1 1 1 1 Peptidase family M3 DUF3198 PF11433.8 CDJ42299.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) XhlA PF10779.9 CDJ42300.1 - 0.0094 16.1 3.9 0.012 15.8 0.6 2.8 2 0 0 2 2 2 1 Haemolysin XhlA ArdA PF07275.11 CDJ42300.1 - 3 8.4 5.9 1.1 9.8 0.9 2.6 1 1 2 3 3 3 0 Antirestriction protein (ArdA) zf-CCHC PF00098.23 CDJ42301.1 - 3e-05 23.9 1.7 3e-05 23.9 1.7 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ42301.1 - 0.12 12.2 0.7 0.3 10.9 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Anti-TRAP PF15777.5 CDJ42301.1 - 0.69 9.9 0.1 0.69 9.9 0.1 2.6 1 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF775 PF05603.12 CDJ42302.1 - 2.5 7.6 6.5 7.2 6.1 6.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF775) FeS_assembly_P PF01883.19 CDJ42303.1 - 0.0013 18.8 0.3 2.5 8.3 0.0 2.7 2 1 0 2 2 2 2 Iron-sulfur cluster assembly protein HTH_32 PF13565.6 CDJ42303.1 - 0.11 13.1 0.3 0.32 11.6 0.3 1.7 1 0 0 1 1 1 0 Homeodomain-like domain zf-CCCH PF00642.24 CDJ42304.1 - 1.5e-11 43.9 16.8 0.00081 19.2 0.5 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ42304.1 - 3.6e-08 33.0 11.9 1.3e-05 24.8 1.1 3.4 3 0 0 3 3 3 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDJ42304.1 - 4.6e-08 32.8 20.1 0.00081 19.4 2.3 3.5 3 0 0 3 3 3 3 Zinc finger domain Scs3p PF10261.9 CDJ42304.1 - 0.019 14.5 0.7 0.054 13.0 0.7 1.8 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM zf-CCCH_3 PF15663.5 CDJ42304.1 - 0.15 12.3 8.4 0.09 13.0 2.9 3.0 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDJ42304.1 - 0.52 10.9 9.1 0.95 10.0 0.1 3.3 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger PFK PF00365.20 CDJ42305.1 - 1.7e-37 129.3 0.9 1.4e-34 119.7 0.0 3.8 3 1 0 3 3 3 3 Phosphofructokinase Btz PF09405.10 CDJ42307.1 - 1.9e-09 37.9 15.2 1.9e-09 37.9 15.2 2.8 3 1 1 4 4 4 1 CASC3/Barentsz eIF4AIII binding DUF4407 PF14362.6 CDJ42307.1 - 0.49 9.7 2.3 0.7 9.2 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L15e PF00827.17 CDJ42311.1 - 2.4e-84 281.8 10.2 2.7e-84 281.6 10.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 BCIP PF13862.6 CDJ42312.1 - 8e-32 110.7 0.1 8e-32 110.7 0.1 3.0 2 1 0 2 2 2 1 p21-C-terminal region-binding protein PP2C PF00481.21 CDJ42313.1 - 3.3e-36 125.2 0.0 4.7e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C BRCT_2 PF16589.5 CDJ42313.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain DA1-like PF12315.8 CDJ42315.1 - 1.9e-08 34.0 0.3 6e-07 29.0 0.3 2.5 1 1 0 1 1 1 1 Protein DA1 RRM_1 PF00076.22 CDJ42316.1 - 0.00014 21.7 0.2 0.47 10.3 0.0 3.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V-ATPase_G PF03179.15 CDJ42317.1 - 6e-05 23.5 10.7 0.00011 22.6 10.7 1.4 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 CDJ42317.1 - 0.00025 20.5 9.4 0.00041 19.8 9.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ATP-synt_B PF00430.18 CDJ42317.1 - 0.18 11.9 16.6 0.23 11.5 15.4 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 CDJ42317.1 - 0.46 10.9 15.1 0.95 9.9 15.1 1.5 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit PNK3P PF08645.11 CDJ42318.1 - 7e-39 133.1 0.0 5.4e-38 130.2 0.0 2.0 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 CDJ42318.1 - 6.7e-10 39.3 0.2 0.00012 22.2 0.0 2.7 1 1 1 2 2 2 2 AAA domain tRNA_lig_kinase PF08303.11 CDJ42318.1 - 6.3e-06 26.4 0.0 9.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_16 PF13191.6 CDJ42318.1 - 5.5e-05 23.6 0.6 0.00024 21.5 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDJ42318.1 - 0.0011 19.2 0.2 0.003 17.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 CDJ42318.1 - 0.0012 19.1 0.1 0.0095 16.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CDJ42318.1 - 0.0035 17.9 0.1 0.0096 16.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDJ42318.1 - 0.0059 16.3 0.0 0.038 13.7 0.0 2.3 3 0 0 3 3 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ42318.1 - 0.011 15.7 0.0 0.04 13.8 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase Viral_helicase1 PF01443.18 CDJ42318.1 - 0.013 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 CDJ42318.1 - 0.018 15.1 0.0 0.041 14.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 CDJ42318.1 - 0.029 14.3 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 CDJ42318.1 - 0.031 14.8 0.0 0.065 13.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 CDJ42318.1 - 0.039 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CDJ42318.1 - 0.05 13.6 0.0 0.19 11.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 CDJ42318.1 - 0.058 12.7 0.0 0.058 12.7 0.0 2.1 2 1 0 2 2 2 0 Zeta toxin NACHT PF05729.12 CDJ42318.1 - 0.058 13.3 0.8 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain HAD_2 PF13419.6 CDJ42318.1 - 0.064 13.3 0.3 10 6.1 0.1 3.2 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ42318.1 - 0.068 13.6 0.5 1 9.7 0.5 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase 6PF2K PF01591.18 CDJ42318.1 - 0.084 12.2 0.4 6.7 5.9 0.0 2.2 1 1 0 2 2 2 0 6-phosphofructo-2-kinase cobW PF02492.19 CDJ42318.1 - 0.13 11.8 0.1 0.31 10.6 0.0 1.8 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CDJ42318.1 - 0.16 10.9 0.0 0.35 9.8 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 CDJ42318.1 - 0.21 12.0 0.3 0.67 10.4 0.1 1.9 1 1 1 2 2 2 0 AAA domain KTI12 PF08433.10 CDJ42318.1 - 0.23 10.9 3.7 0.83 9.0 0.2 2.3 2 1 0 3 3 2 0 Chromatin associated protein KTI12 CEP209_CC5 PF16574.5 CDJ42319.1 - 0.027 14.6 0.4 0.027 14.6 0.4 1.9 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 Molybdopterin_N PF18364.1 CDJ42319.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain DUF3669 PF12417.8 CDJ42319.1 - 0.16 12.2 1.6 3.9 7.7 0.1 3.0 3 1 1 4 4 4 0 Zinc finger protein START PF01852.19 CDJ42325.1 - 9.4e-22 77.5 0.2 1.5e-21 76.8 0.2 1.3 1 0 0 1 1 1 1 START domain ORC6 PF05460.13 CDJ42325.1 - 0.092 12.0 4.6 0.18 11.0 4.6 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF3138 PF11336.8 CDJ42328.1 - 0.012 14.3 0.6 0.012 14.3 0.6 4.9 6 0 0 6 6 6 0 Protein of unknown function (DUF3138) Sec1 PF00995.23 CDJ42329.1 - 2.2e-61 208.8 0.4 2.5e-61 208.6 0.4 1.0 1 0 0 1 1 1 1 Sec1 family ABC_tran_CTD PF16326.5 CDJ42330.1 - 0.045 14.0 2.6 0.084 13.1 2.6 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain SKA2 PF16740.5 CDJ42330.1 - 0.056 13.2 2.4 0.097 12.5 2.4 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Utp14 PF04615.13 CDJ42330.1 - 3.9 5.9 34.9 5.1 5.5 34.9 1.1 1 0 0 1 1 1 0 Utp14 protein RskA PF10099.9 CDJ42331.1 - 0.0046 17.3 11.6 0.0046 17.3 11.6 1.9 1 1 1 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ42331.1 - 1.2 9.1 13.3 1.4 8.8 13.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ42331.1 - 1.7 8.2 12.0 2.3 7.8 12.0 1.2 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ42332.1 - 0.0083 16.4 9.2 0.0083 16.4 9.2 7.3 1 1 4 5 5 5 1 Anti-sigma-K factor rskA DUF1685 PF07939.11 CDJ42332.1 - 0.14 11.9 4.9 0.065 13.0 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1685) AMP-binding PF00501.28 CDJ42333.1 - 0.11 11.1 0.0 0.28 9.7 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme BRCT PF00533.26 CDJ42333.1 - 0.27 11.6 0.7 34 4.9 0.0 3.6 5 0 0 5 5 5 0 BRCA1 C Terminus (BRCT) domain TFIIA PF03153.13 CDJ42333.1 - 0.64 9.9 18.8 0.31 11.0 4.9 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ42333.1 - 6.3 6.3 17.6 0.11 12.0 3.1 2.3 2 0 0 2 2 2 0 Spt20 family HHV6-IE PF03753.13 CDJ42334.1 - 0.26 8.7 1.5 0.38 8.1 1.5 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein MraY_sig1 PF10555.9 CDJ42334.1 - 0.36 10.5 1.7 0.68 9.6 1.7 1.5 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Epimerase PF01370.21 CDJ42335.1 - 6.3e-41 140.4 0.0 8.4e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ42335.1 - 4.4e-05 23.0 0.0 6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CDJ42335.1 - 0.00033 19.8 0.0 0.0014 17.7 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDJ42335.1 - 0.0094 15.1 0.0 0.015 14.4 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CDJ42335.1 - 0.064 12.4 0.3 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein TIP49 PF06068.13 CDJ42336.1 - 9.6e-151 501.9 1.5 3.1e-134 447.6 0.0 2.1 2 0 0 2 2 2 2 TIP49 P-loop domain TIP49_C PF17856.1 CDJ42336.1 - 1.4e-19 70.0 0.0 6.8e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 CDJ42336.1 - 1.4e-07 32.0 0.1 0.001 19.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ42336.1 - 0.0029 17.9 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CDJ42336.1 - 0.047 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 CDJ42336.1 - 0.073 12.8 0.1 18 5.1 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 CDJ42336.1 - 0.08 13.3 0.9 1.2 9.4 0.9 2.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CDJ42336.1 - 0.14 12.2 0.0 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CDJ42336.1 - 0.15 11.1 0.1 0.25 10.4 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Glyco_transf_17 PF04724.13 CDJ42337.1 - 1.4e-20 73.7 0.1 8e-20 71.2 0.1 2.0 2 1 0 2 2 2 1 Glycosyltransferase family 17 CytB6-F_Fe-S PF08802.10 CDJ42339.1 - 0.048 13.7 2.1 0.098 12.7 2.1 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit E1-E2_ATPase PF00122.20 CDJ42340.1 - 2.5e-46 157.5 0.7 2.5e-46 157.5 0.7 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 CDJ42340.1 - 1.3e-14 53.6 0.7 5.1e-14 51.7 0.0 2.3 2 1 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CDJ42340.1 - 1.8e-11 43.9 0.0 8.1e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDJ42340.1 - 0.032 14.5 12.3 0.023 15.0 8.4 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Macoilin PF09726.9 CDJ42341.1 - 0.02 13.5 8.2 0.023 13.3 8.2 1.0 1 0 0 1 1 1 0 Macoilin family DUF5320 PF17253.2 CDJ42341.1 - 0.12 13.4 6.9 0.88 10.7 2.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Mod_r PF07200.13 CDJ42341.1 - 0.16 12.1 9.8 1.4 9.0 1.1 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ERM PF00769.19 CDJ42341.1 - 0.82 9.4 17.3 0.91 9.3 17.3 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family APG6_N PF17675.1 CDJ42341.1 - 4 8.0 15.3 2.5 8.6 2.5 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region GHMP_kinases_N PF00288.26 CDJ42343.1 - 0.5 10.6 7.5 3.7 7.9 0.5 2.4 2 0 0 2 2 2 0 GHMP kinases N terminal domain DUF3138 PF11336.8 CDJ42343.1 - 9.6 4.7 14.4 13 4.2 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SR-25 PF10500.9 CDJ42344.1 - 0.0032 17.1 13.3 0.0044 16.7 13.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2946 PF11162.8 CDJ42344.1 - 7 7.3 14.5 0.74 10.5 6.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2946) DUF755 PF05501.11 CDJ42344.1 - 7.2 6.9 14.0 0.5 10.6 7.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Solute_trans_a PF03619.16 CDJ42345.1 - 1.8e-54 185.0 3.9 6.5e-51 173.4 0.9 2.1 2 0 0 2 2 2 2 Organic solute transporter Ostalpha SR-25 PF10500.9 CDJ42348.1 - 0.0084 15.7 34.1 0.012 15.3 34.1 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.12 CDJ42348.1 - 0.054 13.3 17.6 0.064 13.1 17.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCDC106 PF15794.5 CDJ42348.1 - 0.14 11.9 22.6 0.18 11.5 22.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 GAGA_bind PF06217.12 CDJ42348.1 - 0.43 10.8 16.5 0.53 10.5 16.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.14 CDJ42348.1 - 0.44 8.8 20.8 0.5 8.6 20.8 1.0 1 0 0 1 1 1 0 CDC45-like protein MID_MedPIWI PF18296.1 CDJ42348.1 - 0.74 9.6 11.9 0.83 9.4 11.9 1.1 1 0 0 1 1 1 0 MID domain of medPIWI EOS1 PF12326.8 CDJ42348.1 - 0.87 9.5 7.6 1.1 9.2 7.6 1.3 1 0 0 1 1 1 0 N-glycosylation protein Dsh_C PF12316.8 CDJ42348.1 - 0.91 9.9 11.6 1.1 9.6 11.6 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Transformer PF06495.11 CDJ42348.1 - 1 9.4 13.6 1.2 9.3 13.6 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein DUF913 PF06025.12 CDJ42348.1 - 1.3 7.9 8.9 1.4 7.8 8.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 CDJ42348.1 - 2.3 7.3 12.4 2.8 7.1 12.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3827 PF12877.7 CDJ42348.1 - 3.2 6.0 16.3 3.6 5.9 16.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Vfa1 PF08432.10 CDJ42348.1 - 4.4 7.6 30.4 1.6 9.0 27.7 1.4 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SLC12 PF03522.15 CDJ42348.1 - 4.5 6.2 17.8 5.5 5.9 17.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Smg8_Smg9 PF10220.9 CDJ42348.1 - 4.5 5.5 16.2 5.5 5.2 16.2 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Med19 PF10278.9 CDJ42348.1 - 5 7.0 35.5 0.94 9.4 31.8 1.6 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 XRN_M PF17846.1 CDJ42348.1 - 6.7 5.5 15.9 7.8 5.3 15.9 1.0 1 0 0 1 1 1 0 Xrn1 helical domain NPR3 PF03666.13 CDJ42348.1 - 7 5.3 19.6 8.4 5.1 19.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MCM_bind PF09739.9 CDJ42348.1 - 7.4 4.9 17.2 8.8 4.6 17.2 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor AAA_11 PF13086.6 CDJ42348.1 - 8.7 6.0 17.1 11 5.7 17.1 1.2 1 0 0 1 1 1 0 AAA domain FGF-BP1 PF06473.12 CDJ42348.1 - 9.9 5.9 25.4 19 5.0 25.4 1.4 1 1 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) BCDHK_Adom3 PF10436.9 CDJ42349.1 - 0.39 10.5 7.5 0.078 12.8 2.8 2.1 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF3896 PF13035.6 CDJ42349.1 - 0.72 10.1 3.0 1.9 8.7 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) AP2 PF00847.20 CDJ42350.1 - 1.6e-15 57.1 4.6 3.4e-12 46.4 0.1 2.5 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.6 CDJ42350.1 - 2.3e-05 24.6 0.0 5.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AP2-coincident C-terminal Got1 PF04178.12 CDJ42351.1 - 5e-30 104.2 10.0 6.8e-30 103.8 10.0 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Ribosomal_L34e PF01199.18 CDJ42352.1 - 5.5e-35 119.6 5.1 5.5e-35 119.6 5.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L34e zf-3CxxC_2 PF17180.4 CDJ42352.1 - 0.047 14.4 2.0 0.047 14.4 2.0 1.8 2 0 0 2 2 2 0 Zinc-binding domain PDGF PF00341.17 CDJ42352.1 - 0.62 10.4 7.2 4.9 7.5 2.8 2.3 2 0 0 2 2 2 0 PDGF/VEGF domain zinc_ribbon_12 PF11331.8 CDJ42352.1 - 3.8 7.4 6.1 0.87 9.4 0.2 2.6 2 1 1 3 3 3 0 Probable zinc-ribbon domain FtsJ PF01728.19 CDJ42353.1 - 1.9e-54 184.5 0.0 2.3e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 CDJ42353.1 - 0.0008 19.2 0.0 0.01 15.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ42353.1 - 0.0024 18.5 0.0 0.0057 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ42353.1 - 0.0069 16.2 0.0 0.028 14.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain NSP16 PF06460.12 CDJ42353.1 - 0.0096 15.1 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Coronavirus NSP16 NUDIX_2 PF13869.6 CDJ42354.1 - 9.3e-55 185.1 0.0 1.2e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase DUF667 PF05018.13 CDJ42355.1 - 1.8e-13 50.6 0.1 2.2e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF667) RCC1_2 PF13540.6 CDJ42357.1 - 0.17 11.7 1.3 0.46 10.4 0.2 2.3 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat TMEM95 PF15203.6 CDJ42357.1 - 1.6 8.4 5.2 0.44 10.2 0.5 2.4 2 1 1 3 3 3 0 TMEM95 family Peptidase_M22 PF00814.25 CDJ42358.1 - 2e-75 254.0 0.1 3.6e-55 187.6 0.1 2.1 1 1 1 2 2 2 2 Glycoprotease family ATP-synt_C PF00137.21 CDJ42359.1 - 9.4e-31 106.0 32.3 4.9e-19 68.4 13.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.13 CDJ42359.1 - 4.4 5.7 6.8 11 4.4 0.6 2.4 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Mtc PF03820.17 CDJ42360.1 - 3.3e-65 220.2 0.6 7e-54 183.0 0.4 2.0 1 1 1 2 2 2 2 Tricarboxylate carrier RAP PF08373.10 CDJ42363.1 - 2.1e-10 40.5 0.0 4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 RAP domain RskA PF10099.9 CDJ42363.1 - 0.0016 18.8 10.9 0.0016 18.8 10.9 4.9 3 3 1 4 4 4 1 Anti-sigma-K factor rskA Tmemb_cc2 PF10267.9 CDJ42363.1 - 2.5 7.2 9.9 0.75 8.9 0.6 2.2 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Spt20 PF12090.8 CDJ42365.1 - 3.7 7.1 26.4 3.7 7.1 26.4 1.2 1 0 0 1 1 1 0 Spt20 family IHABP4_N PF16174.5 CDJ42365.1 - 5.5 7.6 16.8 5.9 7.5 16.8 1.0 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal RAB3GAP2_N PF14655.6 CDJ42365.1 - 5.5 6.1 9.4 5.8 6.1 9.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TMEM154 PF15102.6 CDJ42365.1 - 6.1 6.7 7.2 6.7 6.6 7.2 1.1 1 0 0 1 1 1 0 TMEM154 protein family MRI PF15325.6 CDJ42365.1 - 7.5 7.7 8.8 8 7.6 8.8 1.0 1 0 0 1 1 1 0 Modulator of retrovirus infection DnaJ_C PF01556.18 CDJ42368.1 - 9.8e-35 119.8 0.1 1.5e-34 119.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDJ42368.1 - 2.7e-24 85.1 1.8 4.1e-24 84.5 1.1 1.7 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CDJ42368.1 - 0.046 14.1 3.8 0.098 13.0 3.8 1.5 1 0 0 1 1 1 0 DnaJ central domain TB PF00683.17 CDJ42368.1 - 0.11 12.3 0.5 0.23 11.2 0.5 1.5 1 0 0 1 1 1 0 TB domain Pkinase PF00069.25 CDJ42369.1 - 3.6e-16 59.3 0.0 5.8e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ42369.1 - 6.1e-08 32.3 0.0 1.7e-07 30.8 0.0 1.7 1 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ42369.1 - 8.7e-07 28.5 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SUIM_assoc PF16619.5 CDJ42369.1 - 0.036 14.1 0.6 0.11 12.5 0.6 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RIO1 PF01163.22 CDJ42369.1 - 0.04 13.5 0.0 0.098 12.3 0.0 1.6 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 CDJ42369.1 - 1.4 8.8 9.1 0.06 13.3 0.3 3.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ42370.1 - 1e-05 25.1 0.0 1.8e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ42370.1 - 1.2e-05 24.8 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ42370.1 - 7e-05 22.3 0.0 9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain IGR PF09597.10 CDJ42370.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 IGR protein motif Pro_isomerase PF00160.21 CDJ42371.1 - 2.6e-41 141.5 0.0 2.9e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Solute_trans_a PF03619.16 CDJ42373.1 - 2.5e-07 30.5 0.0 4.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Pkinase PF00069.25 CDJ42374.1 - 1.2e-05 24.8 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ42374.1 - 0.0001 21.7 0.0 0.00096 18.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kinase-like PF14531.6 CDJ42375.1 - 0.00085 18.7 0.0 0.0024 17.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 CDJ42375.1 - 0.018 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 CDJ42376.1 - 0.00018 21.0 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ42376.1 - 0.00025 20.5 0.0 0.00044 19.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ42376.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase CAP59_mtransfer PF11735.8 CDJ42377.1 - 0.055 13.2 1.5 0.062 13.0 1.5 1.1 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 CSRNP_N PF16019.5 CDJ42377.1 - 0.075 12.9 4.6 0.085 12.8 4.6 1.0 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Seryl_tRNA_N PF02403.22 CDJ42377.1 - 0.26 11.6 7.9 0.32 11.2 7.9 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 CDJ42377.1 - 0.76 8.8 7.0 0.94 8.5 7.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UCH PF00443.29 CDJ42379.1 - 1.1e-22 80.7 0.0 1.3e-21 77.3 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ42379.1 - 1.8e-11 44.2 0.5 5.8e-06 26.1 0.0 4.7 5 1 0 6 6 6 2 Ubiquitin carboxyl-terminal hydrolase RskA PF10099.9 CDJ42380.1 - 0.012 15.9 0.3 0.012 15.9 0.3 7.4 2 2 2 4 4 4 0 Anti-sigma-K factor rskA Acyltransferase PF01553.21 CDJ42381.1 - 2.7e-08 33.5 0.0 4.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Cyt_bd_oxida_II PF02322.15 CDJ42381.1 - 1.1 8.6 10.3 1.7 7.9 10.3 1.3 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Arm PF00514.23 CDJ42382.1 - 0.001 19.0 0.5 10 6.3 0.0 4.1 3 1 1 4 4 4 1 Armadillo/beta-catenin-like repeat SET PF00856.28 CDJ42382.1 - 0.015 15.7 1.9 0.066 13.6 0.1 2.2 2 0 0 2 2 2 0 SET domain Atx10homo_assoc PF09759.9 CDJ42382.1 - 0.028 14.4 0.4 0.5 10.4 0.0 2.9 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain SUIM_assoc PF16619.5 CDJ42382.1 - 0.03 14.4 1.9 0.03 14.4 1.9 6.5 3 2 2 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 DUF2999 PF11212.8 CDJ42382.1 - 0.04 14.2 0.6 0.7 10.2 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) FPL PF09758.9 CDJ42382.1 - 0.044 13.8 0.1 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein TFIIA PF03153.13 CDJ42382.1 - 0.048 13.7 57.0 0.6 10.1 5.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit V-ATPase_H_C PF11698.8 CDJ42382.1 - 0.25 11.5 2.3 7 6.8 0.1 2.8 2 1 1 3 3 3 0 V-ATPase subunit H Fumerase PF05681.14 CDJ42383.1 - 1.7e-83 280.2 0.0 2.2e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 CDJ42383.1 - 6e-83 277.2 0.0 9.2e-83 276.6 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus MSA-2c PF12238.8 CDJ42385.1 - 2.7 7.9 11.9 0.75 9.8 5.5 3.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c Frankia_peptide PF14407.6 CDJ42386.1 - 0.054 13.5 0.1 0.15 12.1 0.1 1.8 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. SNF2_N PF00176.23 CDJ42388.1 - 2e-23 82.7 0.2 7.1e-17 61.1 0.0 3.5 2 2 0 2 2 2 2 SNF2 family N-terminal domain BTK PF00779.19 CDJ42388.1 - 4.1 7.3 5.7 1.9 8.4 1.6 2.4 2 0 0 2 2 2 0 BTK motif Glycos_transf_4 PF00953.21 CDJ42390.1 - 5.9e-21 75.1 12.1 6.4e-13 49.0 0.9 3.1 3 0 0 3 3 3 2 Glycosyl transferase family 4 Fer2_3 PF13085.6 CDJ42391.1 - 2.5e-30 104.7 0.0 4.6e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CDJ42391.1 - 5.4e-10 39.7 4.8 5.4e-10 39.7 4.8 2.1 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CDJ42391.1 - 6e-07 29.8 17.3 1.1e-06 28.9 5.5 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CDJ42391.1 - 3.9e-06 26.9 2.7 3.9e-06 26.9 2.7 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CDJ42391.1 - 0.0039 17.1 4.6 0.042 13.8 1.2 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 CDJ42391.1 - 0.0071 16.9 4.9 0.0071 16.9 4.9 2.8 2 2 0 2 2 2 1 4Fe-4S dicluster domain Ribosomal_L5_C PF00673.21 CDJ42392.1 - 1.5e-22 79.5 0.0 2.3e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CDJ42392.1 - 1.3e-20 73.5 0.0 2.5e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 CDJ42392.1 - 0.25 11.1 0.2 0.25 11.1 0.2 1.7 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain TipAS PF07739.13 CDJ42394.1 - 0.062 13.9 1.6 2.1 8.9 0.0 3.4 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain Zw10 PF06248.13 CDJ42395.1 - 0.029 13.0 0.1 0.037 12.6 0.1 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Apolipoprotein PF01442.18 CDJ42395.1 - 0.045 13.6 0.2 0.072 13.0 0.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CdvA PF18822.1 CDJ42395.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 CdvA-like coiled-coil domain ADH_zinc_N PF00107.26 CDJ42396.1 - 4.8e-24 84.8 0.0 7.2e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDJ42396.1 - 6.4e-16 58.2 2.3 6.4e-16 58.2 2.3 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 CDJ42396.1 - 8.8e-05 22.1 0.2 0.00016 21.2 0.2 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 CDJ42396.1 - 0.00046 19.8 0.1 0.00066 19.3 0.1 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 CDJ42396.1 - 0.0035 16.7 0.3 0.0053 16.1 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.25 CDJ42397.1 - 1.9e-68 230.7 0.0 2.3e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ42397.1 - 7.3e-34 117.2 0.0 9.1e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ42397.1 - 3.2e-07 30.0 0.0 3.1e-05 23.4 0.0 2.7 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.14 CDJ42397.1 - 1.9e-05 24.2 0.0 3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ42397.1 - 0.00021 21.3 0.0 0.14 12.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ42397.1 - 0.031 13.9 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Cytokin-bind PF09265.10 CDJ42397.1 - 0.13 11.6 0.0 0.33 10.3 0.0 1.6 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding RRM_1 PF00076.22 CDJ42398.1 - 1.8e-18 66.1 0.0 2.7e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ42398.1 - 0.0054 16.7 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RhoGEF67_u2 PF16614.5 CDJ42398.1 - 0.091 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 FlhD PF05247.13 CDJ42401.1 - 0.016 15.4 0.3 0.2 11.9 0.0 2.7 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhD) TMEM119 PF15724.5 CDJ42402.1 - 0.019 15.1 1.3 0.019 15.1 1.3 1.8 1 1 1 2 2 2 0 TMEM119 family Porin_3 PF01459.22 CDJ42403.1 - 4.3e-23 82.1 0.0 6e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic porin NIF PF03031.18 CDJ42404.1 - 7.1e-22 77.9 0.0 1.3e-21 77.0 0.0 1.4 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Ndc1_Nup PF09531.10 CDJ42404.1 - 0.98 8.0 5.0 1.4 7.5 5.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ42404.1 - 1.1 7.9 2.6 1.7 7.3 2.6 1.2 1 0 0 1 1 1 0 Presenilin RFamide_26RFa PF11109.8 CDJ42404.1 - 4.6 7.8 9.9 5.5 7.5 0.2 2.6 2 0 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 Steroid_dh PF02544.16 CDJ42405.1 - 1.8e-33 115.6 7.8 2.4e-27 95.8 1.3 3.5 3 1 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CDJ42405.1 - 0.62 9.5 4.5 2.4 7.6 3.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1295) PSS PF03034.15 CDJ42406.1 - 4.3e-46 157.9 2.1 5.8e-31 108.2 1.6 2.1 1 1 1 2 2 2 2 Phosphatidyl serine synthase Polysacc_synt_C PF14667.6 CDJ42406.1 - 3.4 7.7 9.5 8.5 6.4 1.3 3.4 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain MFS_1 PF07690.16 CDJ42407.1 - 2e-26 92.8 41.3 2e-26 92.8 41.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CDJ42407.1 - 1.6e-05 23.4 3.3 4.4e-05 22.0 0.1 2.6 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family HECT_2 PF09814.9 CDJ42410.1 - 0.0089 14.9 1.7 0.17 10.7 1.1 2.5 2 1 0 2 2 2 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 CDJ42410.1 - 0.087 13.0 0.3 0.53 10.5 0.0 2.3 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Spt20 PF12090.8 CDJ42410.1 - 0.57 9.8 6.1 0.99 9.0 6.1 1.3 1 0 0 1 1 1 0 Spt20 family LYTB PF02401.18 CDJ42411.1 - 4.6e-70 235.9 4.0 8.7e-57 192.4 1.2 2.2 2 0 0 2 2 2 2 LytB protein PI3K_1B_p101 PF10486.9 CDJ42411.1 - 0.046 11.5 2.4 0.085 10.6 2.4 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pap_E4 PF02711.14 CDJ42411.1 - 0.07 14.1 0.7 0.2 12.7 0.7 1.8 1 0 0 1 1 1 0 E4 protein TSNR_N PF04705.12 CDJ42411.1 - 0.094 12.8 0.1 0.48 10.5 0.0 2.1 2 0 0 2 2 2 0 Thiostrepton-resistance methylase, N terminus DUF1635 PF07795.11 CDJ42411.1 - 2.1 8.2 7.6 0.12 12.2 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) zf-RING_UBOX PF13445.6 CDJ42412.1 - 2.8e-05 24.1 1.5 8.3e-05 22.5 1.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ42412.1 - 0.00019 21.2 1.9 0.00051 19.9 1.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ42412.1 - 0.0015 18.3 2.9 0.0015 18.3 2.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ42412.1 - 0.0018 18.1 1.0 0.0018 18.1 1.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ42412.1 - 0.003 17.9 1.6 0.008 16.5 1.6 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CDJ42412.1 - 0.0048 16.7 3.2 0.014 15.3 3.2 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CDJ42412.1 - 0.0056 16.8 0.6 0.0056 16.8 0.6 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDJ42412.1 - 0.0096 15.9 0.5 0.0096 15.9 0.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain SUIM_assoc PF16619.5 CDJ42413.1 - 0.00016 21.7 11.0 0.048 13.7 1.0 3.1 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Collagen PF01391.18 CDJ42413.1 - 0.00057 19.6 5.3 0.0011 18.7 5.3 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) GHMP_kinases_N PF00288.26 CDJ42413.1 - 0.12 12.6 7.9 2.1 8.7 0.9 3.3 3 0 0 3 3 3 0 GHMP kinases N terminal domain DUF2380 PF09533.10 CDJ42413.1 - 5.2 6.6 7.1 1.5 8.4 0.9 2.6 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) SUIM_assoc PF16619.5 CDJ42414.1 - 0.0052 16.8 26.1 0.097 12.7 2.6 3.8 3 1 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 FlxA PF14282.6 CDJ42414.1 - 0.045 13.7 0.2 0.045 13.7 0.2 4.9 4 1 0 4 4 4 0 FlxA-like protein Phostensin_N PF13916.6 CDJ42414.1 - 8.4 6.8 18.8 0.16 12.3 6.9 3.4 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal TFIIA PF03153.13 CDJ42415.1 - 0.17 11.8 10.7 0.21 11.6 10.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SH3-WW_linker PF16618.5 CDJ42415.1 - 0.22 12.0 4.5 2.8 8.4 0.5 2.1 2 0 0 2 2 2 0 Linker region between SH3 and WW domains on ARHGAP12 FSA_C PF10479.9 CDJ42415.1 - 2.3 6.2 4.5 3.1 5.8 4.5 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SNARE PF05739.19 CDJ42418.1 - 2.7e-11 43.3 1.0 8.2e-11 41.7 0.3 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 CDJ42418.1 - 3.4e-06 26.9 3.0 9.3e-06 25.4 3.0 1.8 1 1 0 1 1 1 1 Syntaxin Syntaxin-6_N PF09177.11 CDJ42418.1 - 0.015 15.9 1.3 0.75 10.4 0.1 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal F_actin_bind PF08919.10 CDJ42418.1 - 0.016 15.3 1.0 0.043 13.9 0.2 2.0 2 0 0 2 2 2 0 F-actin binding HhH-GPD PF00730.25 CDJ42418.1 - 0.022 15.2 0.0 0.058 13.9 0.0 1.7 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Rho_N PF07498.12 CDJ42418.1 - 0.05 13.5 0.2 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Sod_Ni PF09055.11 CDJ42418.1 - 0.063 13.8 0.4 0.23 12.0 0.0 2.0 2 0 0 2 2 2 0 Nickel-containing superoxide dismutase Spc29 PF17082.5 CDJ42418.1 - 0.066 13.0 3.1 0.12 12.3 0.7 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF948 PF06103.11 CDJ42418.1 - 0.13 12.6 2.2 16 5.8 0.1 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Vac_Fusion PF02346.16 CDJ42418.1 - 0.14 11.8 3.0 1.4 8.6 0.0 3.0 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Turandot PF07240.11 CDJ42418.1 - 0.15 12.1 0.2 5.4 7.0 0.1 2.6 1 1 1 2 2 2 0 Stress-inducible humoral factor Turandot Phage_Mu_Gam PF07352.12 CDJ42418.1 - 0.58 10.0 3.5 8 6.3 0.1 2.3 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF148 PF02520.17 CDJ42418.1 - 2.8 8.1 9.0 1.1 9.4 1.2 3.2 1 1 1 3 3 3 0 Domain of unknown function DUF148 AFG1_ATPase PF03969.16 CDJ42419.1 - 1.5e-65 221.5 0.0 5.2e-61 206.5 0.0 3.1 2 1 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.6 CDJ42419.1 - 0.069 13.4 0.2 4.7 7.5 0.0 3.3 3 1 0 3 3 3 0 AAA domain Bac_DnaA PF00308.18 CDJ42419.1 - 0.079 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein NACHT PF05729.12 CDJ42419.1 - 0.1 12.5 0.1 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain TniB PF05621.11 CDJ42419.1 - 0.13 11.7 0.0 0.47 9.8 0.0 1.9 1 1 1 2 2 2 0 Bacterial TniB protein SUIM_assoc PF16619.5 CDJ42419.1 - 9.4 6.4 7.9 1.1 9.4 1.7 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AP2 PF00847.20 CDJ42420.1 - 2e-14 53.5 1.6 2.2e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.6 CDJ42420.1 - 6.2e-13 48.9 0.0 6.2e-13 48.9 0.0 2.3 2 1 0 2 2 2 1 AP2-coincident C-terminal CENP-T_C PF15511.6 CDJ42422.1 - 6.1e-09 36.0 0.1 7.3e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CDJ42422.1 - 0.00023 21.3 0.0 0.0003 20.9 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CDJ42422.1 - 0.00051 20.4 0.1 0.00073 19.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CDJ42422.1 - 0.00055 20.2 0.0 0.00079 19.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ42422.1 - 0.0013 19.1 0.1 0.0015 18.9 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CDJ42422.1 - 0.023 14.8 0.0 0.026 14.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CDJ42422.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 CDJ42422.1 - 0.066 13.0 0.2 0.081 12.7 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TAFII28 PF04719.14 CDJ42422.1 - 0.069 13.2 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Tic22 PF04278.12 CDJ42423.1 - 0.023 14.1 0.0 3.7 6.8 0.0 2.7 2 1 0 2 2 2 0 Tic22-like family zf-CCCH_4 PF18044.1 CDJ42424.1 - 8.6e-06 25.4 0.5 8.6e-06 25.4 0.5 3.4 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ42424.1 - 5.4e-05 23.0 1.0 5.4e-05 23.0 1.0 3.7 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Caldesmon PF02029.15 CDJ42424.1 - 0.0028 16.5 36.8 0.04 12.7 14.6 2.4 2 0 0 2 2 2 2 Caldesmon Hom_end_hint PF05203.16 CDJ42424.1 - 0.092 12.7 13.1 0.11 12.4 2.1 2.3 2 0 0 2 2 2 0 Hom_end-associated Hint zf-CCCH_2 PF14608.6 CDJ42424.1 - 0.23 12.0 11.8 3.8 8.1 0.0 4.2 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger Mem_trans PF03547.18 CDJ42424.1 - 0.26 9.6 0.3 0.36 9.2 0.3 1.3 1 0 0 1 1 1 0 Membrane transport protein WD40 PF00400.32 CDJ42425.1 - 1.3e-11 44.9 5.7 6.2e-05 23.7 0.1 5.0 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ42425.1 - 0.0023 18.2 0.0 0.2 12.0 0.0 3.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SUIM_assoc PF16619.5 CDJ42425.1 - 0.019 15.0 20.1 0.023 14.8 0.6 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ42425.1 - 0.034 13.1 6.2 0.051 12.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Ge1_WD40 PF16529.5 CDJ42425.1 - 0.037 13.0 0.2 0.078 11.9 0.2 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Spt20 PF12090.8 CDJ42425.1 - 0.073 12.7 14.8 0.12 12.0 3.2 2.2 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 CDJ42425.1 - 0.14 12.1 17.6 0.034 14.1 14.1 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ANAPC_CDC26 PF10471.9 CDJ42425.1 - 0.5 11.2 17.7 4.4 8.2 4.9 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 THOC2_N PF16134.5 CDJ42425.1 - 7.2 5.1 5.6 11 4.6 5.6 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus BUD22 PF09073.10 CDJ42426.1 - 1.5 8.1 13.8 2.5 7.4 13.8 1.3 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 CDJ42426.1 - 2 8.3 20.6 3.2 7.6 20.6 1.3 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ42426.1 - 2.5 6.9 22.1 3.8 6.3 22.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain CbtA PF09490.10 CDJ42427.1 - 0.89 9.3 9.7 0.44 10.3 0.5 2.7 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) YTH PF04146.15 CDJ42428.1 - 2.4e-28 99.2 6.9 7.6e-27 94.3 0.0 3.1 2 1 0 2 2 2 1 YT521-B-like domain ANAPC_CDC26 PF10471.9 CDJ42428.1 - 3.2 8.7 22.0 5.3 7.9 22.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 GET2 PF08690.10 CDJ42429.1 - 9 5.9 9.8 0.79 9.3 0.2 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 DUF2853 PF11015.8 CDJ42430.1 - 0.0089 16.7 0.1 0.027 15.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2853) LisH PF08513.11 CDJ42430.1 - 0.024 14.6 0.2 0.059 13.3 0.2 1.7 1 0 0 1 1 1 0 LisH WD40 PF00400.32 CDJ42430.1 - 0.27 12.2 0.0 0.27 12.2 0.0 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat RskA PF10099.9 CDJ42430.1 - 0.56 10.5 52.7 0.3 11.4 15.1 4.9 3 2 1 4 4 4 0 Anti-sigma-K factor rskA DUF3327 PF11806.8 CDJ42430.1 - 7.5 7.3 8.9 0.39 11.4 0.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3327) RskA PF10099.9 CDJ42431.1 - 0.0098 16.2 5.6 0.0098 16.2 5.6 15.0 2 1 8 11 11 11 2 Anti-sigma-K factor rskA FA_desaturase PF00487.24 CDJ42431.1 - 0.37 10.6 1.6 1.6 8.5 1.6 2.1 1 0 0 1 1 1 0 Fatty acid desaturase PIG-U PF06728.13 CDJ42432.1 - 7.1e-43 147.1 6.5 2.5e-41 142.0 6.4 2.3 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U AIF_C PF14721.6 CDJ42432.1 - 0.18 12.1 0.3 12 6.3 0.0 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Connexin PF00029.19 CDJ42432.1 - 0.19 11.4 0.8 0.85 9.3 0.2 2.4 1 1 1 2 2 2 0 Connexin DUF2561 PF10812.8 CDJ42432.1 - 0.42 10.6 11.6 0.3 11.1 9.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) HA2 PF04408.23 CDJ42432.1 - 2.7 8.3 8.4 0.86 9.9 0.6 2.7 2 0 0 2 2 2 0 Helicase associated domain (HA2) Pkinase PF00069.25 CDJ42433.1 - 0.052 12.9 0.1 0.052 12.9 0.1 2.7 3 0 0 3 3 3 0 Protein kinase domain Med19 PF10278.9 CDJ42433.1 - 1.2 9.1 6.3 2.6 8.0 6.3 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Presenilin PF01080.17 CDJ42433.1 - 1.6 7.4 11.3 2.4 6.8 11.3 1.2 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 CDJ42435.1 - 2.2e-11 43.6 0.0 7.5e-10 38.6 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ42435.1 - 0.00029 20.2 0.0 0.0011 18.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ42436.1 - 7.8e-08 32.0 0.0 2.7e-06 26.9 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain APH PF01636.23 CDJ42436.1 - 0.067 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family PIP5K PF01504.18 CDJ42437.1 - 5.7e-79 265.2 8.2 4.6e-76 255.7 0.0 3.7 3 1 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase LCD1 PF09798.9 CDJ42437.1 - 0.00014 20.6 2.8 0.00014 20.6 2.8 2.2 2 0 0 2 2 1 1 DNA damage checkpoint protein EF-hand_1 PF00036.32 CDJ42437.1 - 0.0022 17.4 0.1 0.0062 16.0 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CDJ42437.1 - 0.036 14.0 0.4 0.13 12.3 0.4 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 CDJ42437.1 - 0.062 13.8 0.0 0.26 11.8 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 CDJ42437.1 - 0.17 11.8 0.0 0.47 10.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair YL1 PF05764.13 CDJ42437.1 - 0.34 11.0 29.6 0.023 14.8 12.8 2.4 2 0 0 2 2 2 0 YL1 nuclear protein MMR1 PF08505.10 CDJ42437.1 - 0.37 11.1 34.1 0.013 15.9 6.7 2.4 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein AAA_23 PF13476.6 CDJ42437.1 - 0.55 10.7 14.1 0.059 13.9 3.1 2.3 2 0 0 2 2 2 0 AAA domain CCSAP PF15748.5 CDJ42437.1 - 0.57 10.3 38.8 0.37 10.9 23.0 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Apt1 PF10351.9 CDJ42437.1 - 1.6 7.5 21.6 0.41 9.4 10.1 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain GET2 PF08690.10 CDJ42437.1 - 4.6 6.8 42.3 0.59 9.8 25.2 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 HSP70 PF00012.20 CDJ42438.1 - 4e-19 68.2 14.2 4e-19 68.2 14.2 3.5 2 1 0 2 2 2 1 Hsp70 protein BUD22 PF09073.10 CDJ42438.1 - 5.1 6.3 58.3 0.31 10.3 36.0 3.3 3 0 0 3 3 3 0 BUD22 zf-HC5HC2H_2 PF13832.6 CDJ42439.1 - 1.8e-07 31.3 6.8 1.8e-07 31.3 6.8 4.3 5 1 0 5 5 5 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDJ42439.1 - 5.1e-07 29.8 8.8 5.1e-07 29.8 8.8 4.6 4 1 1 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.29 CDJ42439.1 - 8.8e-06 25.5 6.2 8.8e-06 25.5 6.2 5.3 5 0 0 5 5 5 1 PHD-finger DUF755 PF05501.11 CDJ42439.1 - 0.0027 18.0 10.2 0.0027 18.0 10.2 8.6 8 2 0 8 8 8 2 Domain of unknown function (DUF755) CAF1 PF04857.20 CDJ42439.1 - 2.6 7.1 10.1 68 2.5 12.7 2.0 2 0 0 2 2 2 0 CAF1 family ribonuclease PH PF00169.29 CDJ42440.1 - 1.4e-06 28.7 0.1 3e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 PH domain PH_10 PF15411.6 CDJ42440.1 - 0.0035 17.6 0.2 0.0053 17.0 0.2 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PBP1_TM PF14812.6 CDJ42440.1 - 0.0075 16.6 0.8 0.016 15.5 0.8 1.5 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2890 PF11081.8 CDJ42440.1 - 0.26 11.4 5.8 0.35 11.0 5.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) LRR_9 PF14580.6 CDJ42441.1 - 3.6e-05 23.3 0.3 6.7e-05 22.5 0.3 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CDJ42441.1 - 0.0005 19.8 2.4 0.059 13.1 0.0 3.6 3 1 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 CDJ42441.1 - 0.0027 18.1 5.0 0.59 10.6 0.0 4.5 3 1 2 5 5 5 1 Leucine Rich repeats (2 copies) DUF4834 PF16118.5 CDJ42441.1 - 0.65 11.0 6.2 0.33 11.9 0.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) G0-G1_switch_2 PF15103.6 CDJ42441.1 - 2.6 8.5 6.8 0.54 10.7 0.8 2.5 3 0 0 3 3 3 0 G0/G1 switch protein 2 TFIIA PF03153.13 CDJ42441.1 - 3.9 7.4 23.1 2.7 7.9 11.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Apolipoprotein PF01442.18 CDJ42443.1 - 0.0038 17.1 0.0 0.025 14.5 0.0 2.1 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain GTP_EFTU_D3 PF03143.17 CDJ42444.1 - 3.1e-20 72.5 0.0 5.4e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDJ42444.1 - 5.2e-16 58.8 1.3 1.9e-15 57.0 1.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.27 CDJ42444.1 - 1.7e-08 34.3 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D4 PF14578.6 CDJ42444.1 - 0.1 12.5 0.3 0.21 11.5 0.3 1.5 1 0 0 1 1 1 0 Elongation factor Tu domain 4 PGI PF00342.19 CDJ42445.1 - 3.6e-131 438.1 0.7 4.2e-131 437.9 0.7 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase YtzH PF14165.6 CDJ42445.1 - 0.098 13.1 0.1 2.9 8.3 0.1 2.4 2 0 0 2 2 2 0 YtzH-like protein DUF3080 PF11279.8 CDJ42455.1 - 0.14 11.4 0.1 0.26 10.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) FERM_M PF00373.18 CDJ42457.1 - 0.0017 18.7 0.0 0.0039 17.6 0.0 1.7 1 0 0 1 1 1 1 FERM central domain PTN13_u3 PF16599.5 CDJ42458.1 - 0.054 13.5 0.2 0.054 13.5 0.2 1.8 2 0 0 2 2 2 0 Unstructured linker region on PTN13 protein between PDZ DUF1180 PF06679.12 CDJ42459.1 - 1 9.8 4.4 5.5 7.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Metallophos PF00149.28 CDJ42465.1 - 6e-19 69.4 0.0 2.6e-15 57.5 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase SUIM_assoc PF16619.5 CDJ42465.1 - 0.0027 17.7 6.6 0.054 13.6 7.4 2.1 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 STPPase_N PF16891.5 CDJ42465.1 - 0.12 12.9 0.7 0.34 11.4 0.7 1.8 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain SQS_PSY PF00494.19 CDJ42467.1 - 0.036 13.6 0.1 0.074 12.5 0.1 1.4 1 0 0 1 1 1 0 Squalene/phytoene synthase HisKA_3 PF07730.13 CDJ42467.1 - 0.088 13.3 1.2 0.21 12.1 0.2 2.2 2 0 0 2 2 2 0 Histidine kinase LcrG PF07216.12 CDJ42469.1 - 0.015 15.2 0.4 6.1 6.8 0.0 2.6 2 0 0 2 2 2 0 LcrG protein B12D PF06522.11 CDJ42469.1 - 0.18 11.6 0.5 1.4 8.8 0.4 2.2 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF883 PF05957.13 CDJ42469.1 - 0.45 11.1 3.0 2.2 8.9 0.2 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Pilin_PilA PF14245.6 CDJ42470.1 - 0.023 14.7 0.6 0.089 12.8 0.6 2.0 1 0 0 1 1 1 0 Type IV pilin PilA AP2 PF00847.20 CDJ42471.1 - 9e-07 29.0 0.5 0.007 16.6 0.7 2.6 2 0 0 2 2 2 2 AP2 domain ProRS-C_1 PF09180.11 CDJ42472.1 - 2.1e-28 98.3 0.0 4.9e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 CDJ42472.1 - 1.2e-22 80.7 0.0 2.6e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 CDJ42472.1 - 3.4e-21 75.6 0.1 5.7e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 CDJ42472.1 - 4.5e-19 68.4 0.0 1.9e-18 66.4 0.0 2.1 3 0 0 3 3 3 1 Anticodon binding domain DUF726 PF05277.12 CDJ42474.1 - 1.1e-108 363.2 0.4 1.5e-108 362.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cutinase PF01083.22 CDJ42474.1 - 0.033 14.2 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Cutinase Abhydrolase_1 PF00561.20 CDJ42474.1 - 0.037 13.7 0.2 0.25 11.0 0.1 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF3040 PF11239.8 CDJ42475.1 - 0.27 11.5 2.2 4.2 7.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Rer1 PF03248.13 CDJ42476.1 - 4e-61 205.7 1.7 4.9e-61 205.4 1.7 1.1 1 0 0 1 1 1 1 Rer1 family Bromodomain PF00439.25 CDJ42477.1 - 1e-32 112.0 0.0 7.2e-17 61.2 0.0 2.4 2 0 0 2 2 2 2 Bromodomain RPA_interact_M PF14767.6 CDJ42477.1 - 2.8 8.6 7.0 20 5.8 0.1 2.9 2 0 0 2 2 2 0 Replication protein A interacting middle Kinase-like PF14531.6 CDJ42478.1 - 7.9e-09 35.2 0.0 5.6e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 CDJ42478.1 - 0.00021 20.7 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ42478.1 - 0.019 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase TadE PF07811.12 CDJ42478.1 - 0.07 13.4 1.5 0.19 12.0 1.5 1.7 1 0 0 1 1 1 0 TadE-like protein Pkinase PF00069.25 CDJ42479.1 - 2.9e-12 46.5 0.0 4.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ42479.1 - 3.2e-10 39.8 0.1 1.1e-09 38.0 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ42479.1 - 1.9e-06 27.4 0.0 3.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MARVEL PF01284.23 CDJ42480.1 - 0.0012 18.9 2.7 0.0012 18.9 2.7 2.1 1 1 1 2 2 2 1 Membrane-associating domain DUF5090 PF17009.5 CDJ42480.1 - 1.2 9.1 6.7 1.5 8.7 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Methyltr_RsmB-F PF01189.17 CDJ42481.1 - 2.5e-40 138.3 0.0 3.6e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 CDJ42481.1 - 1.4e-07 31.4 0.0 2.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 CDJ42481.1 - 9.3e-05 22.6 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 CDJ42481.1 - 0.00012 21.9 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CDJ42481.1 - 0.00034 21.2 0.1 0.0017 19.0 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 CDJ42481.1 - 0.0016 17.6 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin PUA PF01472.20 CDJ42481.1 - 0.0059 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 PUA domain Ubie_methyltran PF01209.18 CDJ42481.1 - 0.018 14.4 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CDJ42481.1 - 0.022 14.6 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 CDJ42481.1 - 0.2 10.7 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CRT-like PF08627.10 CDJ42484.1 - 5.1e-111 370.8 13.9 6e-111 370.6 13.9 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 CDJ42484.1 - 0.00023 21.3 4.5 0.00023 21.3 4.5 3.3 3 0 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 CDJ42484.1 - 0.00023 20.8 3.1 0.00023 20.8 3.1 1.7 2 0 0 2 2 2 1 Solute carrier family 35 UAA PF08449.11 CDJ42484.1 - 0.081 12.1 9.5 0.018 14.3 4.7 1.9 2 0 0 2 2 2 0 UAA transporter family O-antigen_lig PF13425.6 CDJ42484.1 - 0.26 10.0 5.6 0.035 12.9 0.4 2.0 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Pkinase_Tyr PF07714.17 CDJ42485.1 - 1.8e-21 76.6 0.0 1.9e-09 37.2 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 CDJ42485.1 - 7.1e-14 51.8 0.0 1.4e-05 24.7 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain MORN PF02493.20 CDJ42485.1 - 0.12 12.3 1.6 1 9.4 0.0 2.9 3 0 0 3 3 3 0 MORN repeat FliD_N PF02465.18 CDJ42485.1 - 1.5 9.5 4.7 4.4 8.1 4.7 1.7 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus YL1 PF05764.13 CDJ42486.1 - 0.00093 19.4 0.5 0.00099 19.3 0.5 1.1 1 0 0 1 1 1 1 YL1 nuclear protein TMEM220 PF15071.6 CDJ42487.1 - 0.11 13.3 0.3 0.18 12.6 0.3 1.3 1 0 0 1 1 1 0 Transmembrane family 220, helix Inhibitor_I42 PF09394.10 CDJ42488.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.8 1 1 0 1 1 1 0 Chagasin family peptidase inhibitor I42 Inhibitor_I71 PF12628.7 CDJ42488.1 - 0.026 14.4 0.0 0.08 12.8 0.0 1.7 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor Nucleoporin_FG PF13634.6 CDJ42489.1 - 0.00032 21.5 110.3 0.0026 18.6 24.7 6.5 1 1 2 3 3 3 1 Nucleoporin FG repeat region Chorein_N PF12624.7 CDJ42490.1 - 0.064 13.4 0.0 0.064 13.4 0.0 2.7 3 0 0 3 3 3 0 N-terminal region of Chorein or VPS13 XendoU PF09412.10 CDJ42491.1 - 0.051 12.8 2.0 0.1 11.8 2.0 1.4 1 0 0 1 1 1 0 Endoribonuclease XendoU Calici_MSP PF05752.11 CDJ42491.1 - 5.3 6.9 13.7 0.056 13.3 4.5 2.3 2 1 1 3 3 3 0 Calicivirus minor structural protein Pkinase PF00069.25 CDJ42493.1 - 6.8e-36 124.0 0.0 1.2e-34 119.9 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ42493.1 - 1.1e-09 37.9 0.0 0.00038 19.8 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Med3 PF11593.8 CDJ42493.1 - 0.51 9.5 0.0 0.51 9.5 0.0 4.4 3 1 2 5 5 5 0 Mediator complex subunit 3 fungal Sas6_CC PF18594.1 CDJ42493.1 - 3.3 7.6 4.7 0.5 10.2 0.3 2.0 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain RskA PF10099.9 CDJ42493.1 - 6.2 7.1 25.6 0.23 11.7 5.5 3.6 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Miga PF10265.9 CDJ42494.1 - 0.13 11.2 0.3 0.19 10.6 0.3 1.2 1 0 0 1 1 1 0 Mitoguardin Acetyltransf_1 PF00583.25 CDJ42495.1 - 4.1e-12 46.4 0.0 6e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ42495.1 - 3.5e-10 40.2 0.0 5.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ42495.1 - 1.2e-09 38.1 0.0 2.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ42495.1 - 8.7e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CDJ42495.1 - 8.9e-05 23.2 0.0 0.00015 22.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDJ42495.1 - 0.0062 16.6 0.1 0.025 14.7 0.0 2.0 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase DNA_pol_A_exo1 PF01612.20 CDJ42496.1 - 1.3e-28 99.9 0.5 2e-28 99.3 0.5 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HTH_Tnp_Tc5 PF03221.16 CDJ42496.1 - 0.0077 16.2 0.1 0.028 14.4 0.1 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Aldedh PF00171.22 CDJ42497.1 - 9.1e-140 466.2 4.0 2.5e-107 359.3 2.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Adeno_E1B_55K_N PF04623.12 CDJ42497.1 - 5.8 7.7 8.3 1.2 9.8 1.8 3.1 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus Alpha_adaptinC2 PF02883.20 CDJ42498.1 - 1.8e-09 37.8 0.1 3.5e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 Adaptin C-terminal domain Alpha_adaptin_C PF02296.16 CDJ42498.1 - 0.079 13.2 0.0 5.8 7.1 0.0 2.4 1 1 1 2 2 2 0 Alpha adaptin AP2, C-terminal domain DNA_methylase PF00145.17 CDJ42499.1 - 1.1e-12 48.0 21.1 7.6e-09 35.4 0.0 4.2 3 1 0 3 3 3 2 C-5 cytosine-specific DNA methylase adh_short_C2 PF13561.6 CDJ42500.1 - 8.9e-50 169.4 0.2 3.8e-47 160.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ42500.1 - 1e-10 41.4 0.1 1.1e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Enoyl_reductase PF12241.8 CDJ42500.1 - 0.00071 19.0 0.1 0.34 10.2 0.0 2.4 1 1 1 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region Es2 PF09751.9 CDJ42501.1 - 2.2e-10 40.9 6.8 5.4e-06 26.4 0.1 6.5 2 2 3 6 6 6 3 Nuclear protein Es2 YL1 PF05764.13 CDJ42501.1 - 0.0077 16.4 14.4 0.0077 16.4 14.4 5.3 2 2 1 4 4 4 1 YL1 nuclear protein RskA PF10099.9 CDJ42502.1 - 0.012 15.9 1.2 0.012 15.9 1.2 13.5 6 5 5 11 11 11 0 Anti-sigma-K factor rskA DNA_pol_E_B PF04042.16 CDJ42503.1 - 1.4e-14 54.0 1.9 1.4e-14 54.0 1.9 2.1 2 2 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B SUIM_assoc PF16619.5 CDJ42503.1 - 0.0023 17.9 11.9 0.11 12.5 0.8 2.4 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ42503.1 - 0.0039 17.5 0.1 0.0039 17.5 0.1 4.2 2 1 1 3 3 3 2 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ42503.1 - 2.4 7.7 14.5 1.2 8.7 1.4 2.2 2 0 0 2 2 2 0 Spt20 family C2 PF00168.30 CDJ42504.1 - 2.3e-35 121.0 0.1 8e-09 35.7 0.0 7.0 7 0 0 7 7 7 6 C2 domain Ferlin_C PF16165.5 CDJ42504.1 - 0.053 13.5 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Ferlin C-terminus FerI PF08151.12 CDJ42504.1 - 0.078 13.1 0.0 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 FerI (NUC094) domain zf-RING_2 PF13639.6 CDJ42505.1 - 1.2e-09 38.4 12.7 2.1e-09 37.5 12.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CDJ42505.1 - 9.4e-08 31.7 7.3 2.4e-07 30.4 7.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CDJ42505.1 - 1.4e-06 28.1 8.2 2.5e-06 27.3 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ42505.1 - 2.6e-05 23.9 8.6 4.9e-05 23.1 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CDJ42505.1 - 0.0001 21.9 8.5 0.00019 21.0 8.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 CDJ42505.1 - 0.00018 21.7 10.2 0.00059 20.1 10.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CDJ42505.1 - 0.00078 19.4 5.9 0.0016 18.5 5.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CDJ42505.1 - 0.0023 17.9 4.1 0.0052 16.8 4.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CDJ42505.1 - 0.13 12.4 8.2 0.32 11.1 8.2 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_5 PF14634.6 CDJ42505.1 - 0.13 12.2 10.4 0.3 11.1 10.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Caa3_CtaG PF09678.10 CDJ42505.1 - 0.18 11.2 0.2 0.27 10.7 0.2 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) zf-Nse PF11789.8 CDJ42505.1 - 0.2 11.5 5.0 0.36 10.7 5.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 CDJ42505.1 - 0.39 11.0 6.3 0.97 9.8 6.1 1.8 1 1 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.6 CDJ42505.1 - 0.43 10.5 10.1 0.82 9.6 10.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 CDJ42505.1 - 1.8 8.8 10.0 6.4 7.0 10.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 CDJ42505.1 - 1.9 8.7 7.8 3.6 7.8 7.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pox_A_type_inc PF04508.12 CDJ42506.1 - 0.00044 20.0 6.1 0.3 11.0 0.3 3.8 2 1 1 3 3 3 3 Viral A-type inclusion protein repeat Phosphodiest PF01663.22 CDJ42507.1 - 0.00025 20.8 0.0 0.00037 20.2 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1525 PF07511.11 CDJ42508.1 - 6 7.0 5.8 0.74 10.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) SSFA2_C PF14723.6 CDJ42509.1 - 0.089 12.7 0.0 0.092 12.6 0.0 1.0 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus cNMP_binding PF00027.29 CDJ42510.1 - 4e-25 87.7 0.1 1.9e-15 56.7 0.0 2.9 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 CDJ42511.1 - 7e-57 189.5 0.2 4.6e-19 68.3 0.0 4.6 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain EF-hand_1 PF00036.32 CDJ42511.1 - 1.1e-06 27.7 0.5 0.06 12.9 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CDJ42511.1 - 4.5e-06 26.2 0.7 0.29 11.2 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CDJ42511.1 - 6e-05 22.8 1.2 0.67 9.8 0.1 4.2 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.6 CDJ42511.1 - 0.00051 20.4 7.5 0.93 10.0 0.1 4.9 5 1 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ42511.1 - 0.014 14.8 0.0 7.3 6.3 0.0 3.0 2 0 0 2 2 2 0 EF hand EF-hand_11 PF08976.11 CDJ42511.1 - 0.079 13.8 0.0 0.4 11.6 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain WD40_alt PF14077.6 CDJ42511.1 - 0.47 10.4 14.1 5.2 7.0 2.2 4.0 3 0 0 3 3 3 0 Alternative WD40 repeat motif RRM_1 PF00076.22 CDJ42512.1 - 2.8e-17 62.3 0.0 7.3e-12 44.9 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ42512.1 - 0.008 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ42512.1 - 0.027 14.3 0.0 0.096 12.6 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif Lambda_Bor PF06291.11 CDJ42512.1 - 0.12 12.5 0.0 6 7.0 0.0 2.2 2 0 0 2 2 2 0 Bor protein TrmB PF01978.19 CDJ42512.1 - 0.13 12.2 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB PRP21_like_P PF12230.8 CDJ42513.1 - 6.3e-43 147.2 3.3 6.3e-43 147.2 3.3 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CDJ42513.1 - 7.2e-36 122.0 2.7 1.3e-16 60.3 0.2 3.3 3 0 0 3 3 3 2 Surp module DUF1682 PF07946.14 CDJ42513.1 - 0.003 16.8 1.7 0.003 16.8 1.7 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1682) TNT PF14021.6 CDJ42513.1 - 0.13 12.9 0.1 0.34 11.5 0.1 1.7 1 0 0 1 1 1 0 Tuberculosis necrotizing toxin Peptidase_S9 PF00326.21 CDJ42514.1 - 1.4e-27 96.5 0.0 6.8e-22 78.0 0.0 2.6 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ42514.1 - 8.4e-07 28.9 0.0 2.5e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CDJ42514.1 - 0.00033 19.7 0.0 0.00033 19.7 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S28 PF05577.12 CDJ42514.1 - 0.0092 14.8 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Esterase_phd PF10503.9 CDJ42514.1 - 0.021 14.3 0.1 0.063 12.7 0.0 1.8 2 0 0 2 2 2 0 Esterase PHB depolymerase TFIIA PF03153.13 CDJ42514.1 - 0.51 10.3 28.6 0.84 9.6 28.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PapD-like PF14874.6 CDJ42516.1 - 7.1e-05 22.9 0.5 0.98 9.6 0.0 4.3 4 0 0 4 4 4 2 Flagellar-associated PapD-like ASH PF15780.5 CDJ42516.1 - 0.0014 18.8 0.0 6.8 7.0 0.0 5.1 6 0 0 6 6 6 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin HipN PF18253.1 CDJ42517.1 - 3.6e-15 55.3 0.3 8.7e-15 54.1 0.1 1.7 2 0 0 2 2 2 1 Hsp70-interacting protein N N-terminal domain TPR_1 PF00515.28 CDJ42517.1 - 7.9e-13 47.6 4.2 2.3e-08 33.5 0.3 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ42517.1 - 4.7e-11 41.9 8.3 9.8e-07 28.4 0.4 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat STI1 PF17830.1 CDJ42517.1 - 1.8e-10 40.6 2.6 5e-10 39.2 2.6 1.7 1 0 0 1 1 1 1 STI1 domain TPR_16 PF13432.6 CDJ42517.1 - 8.7e-09 35.9 9.8 1.1e-05 26.0 2.7 2.7 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ42517.1 - 1.7e-07 30.8 1.6 0.00012 21.7 0.3 2.5 1 1 1 2 2 2 2 TPR repeat TPR_9 PF13371.6 CDJ42517.1 - 2.8e-05 24.2 1.4 7.8e-05 22.7 0.6 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ42517.1 - 8.6e-05 23.1 3.5 0.00063 20.4 0.6 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ42517.1 - 8.8e-05 22.4 7.3 0.0025 17.9 0.1 3.3 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ42517.1 - 0.00012 22.3 8.8 0.00016 21.9 0.1 2.9 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ42517.1 - 0.0003 21.2 0.9 0.0003 21.2 0.9 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ42517.1 - 0.0027 18.0 1.3 0.056 13.8 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF1641 PF07849.11 CDJ42517.1 - 0.011 15.6 0.1 0.04 13.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) ANAPC3 PF12895.7 CDJ42517.1 - 0.021 15.0 0.9 0.041 14.1 0.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CDJ42517.1 - 0.2 11.6 0.3 0.2 11.6 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PTPRCAP PF15713.5 CDJ42517.1 - 0.29 11.4 8.3 0.13 12.5 1.7 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated TPR_6 PF13174.6 CDJ42517.1 - 1.9 9.3 5.1 24 5.9 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Spc7_N PF15402.6 CDJ42517.1 - 5.4 5.1 12.6 8.4 4.5 12.6 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 BSD PF03909.17 CDJ42518.1 - 3.1e-07 30.3 0.2 0.013 15.5 0.1 3.0 2 0 0 2 2 2 2 BSD domain FTHFS PF01268.19 CDJ42518.1 - 0.039 12.2 0.7 0.06 11.5 0.7 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase DUF3040 PF11239.8 CDJ42518.1 - 1.2 9.5 4.4 0.71 10.2 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) PLDc PF00614.22 CDJ42519.1 - 4.2e-08 33.0 0.0 0.01 16.0 0.0 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CDJ42519.1 - 1.3e-07 31.6 0.0 0.011 15.7 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain USP7_C2 PF14533.6 CDJ42520.1 - 0.049 13.3 1.0 0.12 12.0 1.0 1.6 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal DUF2721 PF11026.8 CDJ42520.1 - 4 7.3 12.6 0.049 13.5 2.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) cwf21 PF08312.12 CDJ42521.1 - 1.1e-07 31.9 8.6 1.1e-07 31.9 8.6 3.0 2 0 0 2 2 2 1 cwf21 domain PI3K_1B_p101 PF10486.9 CDJ42521.1 - 0.0027 15.6 24.7 0.004 15.0 24.7 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CKS PF01111.19 CDJ42523.1 - 1.1e-06 28.7 0.0 3.1e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DnaJ_C PF01556.18 CDJ42524.1 - 1.5e-28 99.8 0.0 2.9e-26 92.3 0.0 2.1 1 1 1 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CDJ42524.1 - 5.1e-08 33.2 11.7 1.3e-07 31.8 11.7 1.8 1 0 0 1 1 1 1 DnaJ central domain PHD_4 PF16866.5 CDJ42524.1 - 0.076 13.1 0.7 0.22 11.7 0.7 1.8 1 0 0 1 1 1 0 PHD-finger Lar_restr_allev PF14354.6 CDJ42524.1 - 0.094 13.1 2.5 0.25 11.8 2.5 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-C3HC4_3 PF13920.6 CDJ42524.1 - 1.2 9.0 6.0 1.2 9.1 1.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TackOD1 PF18551.1 CDJ42524.1 - 3.1 7.4 8.5 4.7 6.8 1.1 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 CDJ42524.1 - 5.4 7.1 12.7 15 5.7 11.8 2.1 1 1 1 2 2 2 0 Double zinc ribbon M20_dimer PF07687.14 CDJ42525.1 - 5.7e-08 32.6 0.0 9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 CDJ42525.1 - 8e-05 22.4 0.0 0.00017 21.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 CDJ42526.1 - 1.2e-09 38.7 11.7 0.14 13.1 0.0 6.6 5 1 0 5 5 5 4 WD domain, G-beta repeat Peptidase_M20 PF01546.28 CDJ42526.1 - 1.5e-09 37.8 0.0 1.2e-06 28.3 0.0 3.4 3 0 0 3 3 3 1 Peptidase family M20/M25/M40 Ephrin_rec_like PF07699.13 CDJ42528.1 - 0.021 14.6 0.7 0.075 12.8 0.7 1.9 1 0 0 1 1 1 0 Putative ephrin-receptor like EMP24_GP25L PF01105.24 CDJ42530.1 - 0.028 14.3 2.4 0.1 12.6 0.3 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Matrilin_ccoil PF10393.9 CDJ42531.1 - 3.4 7.6 7.3 16 5.5 3.3 3.0 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin A_deaminase PF00962.22 CDJ42532.1 - 1.5e-63 215.1 0.0 2.5e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase RRF PF01765.19 CDJ42533.1 - 3.7e-30 105.0 3.3 6.7e-30 104.2 3.3 1.4 1 0 0 1 1 1 1 Ribosome recycling factor RRF_GI PF12614.8 CDJ42533.1 - 0.098 12.8 3.7 0.27 11.4 1.0 2.3 2 0 0 2 2 2 0 Ribosome recycling factor DUF58 PF01882.18 CDJ42533.1 - 0.45 10.8 6.2 1 9.7 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF58 DUF5102 PF17104.5 CDJ42533.1 - 1.5 8.8 10.5 0.1 12.6 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) SpoIIIAH PF12685.7 CDJ42533.1 - 5.7 6.7 16.0 27 4.5 16.0 1.8 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF4201 PF13870.6 CDJ42534.1 - 0.1 12.3 0.7 0.12 12.1 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Macoilin PF09726.9 CDJ42534.1 - 2.7 6.4 10.3 3.1 6.2 10.3 1.0 1 0 0 1 1 1 0 Macoilin family DUF2722 PF10846.8 CDJ42535.1 - 0.0022 17.0 8.9 0.0022 17.0 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ42535.1 - 0.013 15.1 16.4 0.013 15.1 16.4 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ42535.1 - 0.23 11.4 18.1 0.27 11.2 18.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF702 PF05142.12 CDJ42535.1 - 0.28 11.6 4.7 0.31 11.5 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF4834 PF16118.5 CDJ42535.1 - 3.9 8.5 7.4 5.3 8.1 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ42535.1 - 4.1 6.1 6.2 4.2 6.0 6.2 1.1 1 0 0 1 1 1 0 Presenilin PsbQ PF05757.11 CDJ42536.1 - 2.1 8.0 30.2 0.92 9.2 9.5 2.2 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Adaptin_N PF01602.20 CDJ42537.1 - 5e-53 180.4 0.4 8.2e-47 159.9 0.0 3.8 2 1 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 CDJ42537.1 - 0.0022 18.1 0.8 0.38 10.8 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDJ42537.1 - 8.2 7.0 11.6 6.8 7.2 0.3 4.6 4 0 0 4 4 4 0 HEAT repeat SR-25 PF10500.9 CDJ42538.1 - 4e-05 23.3 10.9 4.9e-05 23.1 10.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4519 PF15012.6 CDJ42538.1 - 0.036 14.2 1.2 0.066 13.4 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Ilar_coat PF01787.16 CDJ42538.1 - 0.08 12.7 2.2 0.11 12.3 2.2 1.4 1 0 0 1 1 1 0 Ilarvirus coat protein TFIIA PF03153.13 CDJ42538.1 - 0.21 11.6 10.5 0.21 11.5 10.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ42538.1 - 0.28 11.1 6.3 0.31 11.0 6.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med3 PF11593.8 CDJ42538.1 - 0.34 10.1 8.8 0.43 9.7 8.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spem1 PF15670.5 CDJ42538.1 - 0.36 10.4 13.3 0.56 9.7 13.3 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 FRG2 PF15315.6 CDJ42538.1 - 0.81 9.9 17.1 0.97 9.6 17.1 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 RSRP PF17069.5 CDJ42538.1 - 1.3 8.5 18.7 1.5 8.3 18.7 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Spt20 PF12090.8 CDJ42538.1 - 1.4 8.5 17.6 1.8 8.1 17.6 1.2 1 0 0 1 1 1 0 Spt20 family SprA-related PF12118.8 CDJ42538.1 - 2.7 7.0 13.4 3.7 6.6 13.4 1.1 1 0 0 1 1 1 0 SprA-related family Transposase_21 PF02992.14 CDJ42538.1 - 4.3 6.5 5.6 5.9 6.1 5.6 1.2 1 0 0 1 1 1 0 Transposase family tnp2 Presenilin PF01080.17 CDJ42538.1 - 6.7 5.4 8.6 7.6 5.2 8.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.6 CDJ42538.1 - 8 4.2 13.4 9 4.1 13.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Phage_tail_3 PF08813.11 CDJ42540.1 - 0.011 15.4 1.3 0.024 14.2 0.1 2.1 2 0 0 2 2 2 0 Phage tail tube protein, TTP LptE PF04390.12 CDJ42540.1 - 0.024 15.3 10.1 0.13 13.0 3.7 3.3 2 2 0 2 2 2 0 Lipopolysaccharide-assembly DUF1439 PF07273.12 CDJ42540.1 - 0.071 12.9 3.8 2.7 7.8 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1439) PAD PF03068.15 CDJ42540.1 - 0.69 8.8 3.0 3.3 6.6 1.0 2.3 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) Ribosomal_L18p PF00861.22 CDJ42542.1 - 0.013 15.8 0.1 0.056 13.8 0.1 2.1 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast HSBP1 PF06825.12 CDJ42542.1 - 0.064 13.1 7.1 12 5.9 0.3 4.9 5 1 0 6 6 6 0 Heat shock factor binding protein 1 NPV_P10 PF05531.12 CDJ42542.1 - 1.2 9.7 16.3 26 5.4 0.2 5.3 2 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF4686 PF15742.5 CDJ42542.1 - 6.1 5.9 54.5 0.24 10.5 0.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4686) Nas2_N PF18265.1 CDJ42543.1 - 4.3e-25 87.4 0.0 5.4e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 Nas2 N_terminal domain Tom22 PF04281.13 CDJ42545.1 - 7.8e-07 29.0 0.1 9.6e-07 28.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 SK_channel PF03530.14 CDJ42545.1 - 0.022 14.8 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated SK potassium channel PFK PF00365.20 CDJ42545.1 - 0.054 12.8 0.0 0.066 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosphofructokinase Methyltr_RsmB-F PF01189.17 CDJ42546.1 - 3.4e-27 95.4 0.0 4.1e-19 69.0 0.0 3.7 3 1 0 3 3 3 2 16S rRNA methyltransferase RsmB/F SUIM_assoc PF16619.5 CDJ42546.1 - 0.0034 17.4 3.1 0.013 15.5 0.1 2.6 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Tubulin PF00091.25 CDJ42547.1 - 6.9e-67 225.5 0.0 9.6e-67 225.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ42547.1 - 6e-51 171.9 0.3 1.6e-50 170.5 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDJ42547.1 - 0.039 13.6 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Tubulin domain H_PPase PF03030.16 CDJ42548.1 - 2.8e-83 280.7 2.6 3.9e-83 280.2 2.6 1.1 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase RRM_1 PF00076.22 CDJ42548.1 - 2.9e-12 46.2 0.0 5.4e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) partial_CstF PF15861.5 CDJ42548.1 - 1.3e-08 34.5 0.0 2.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Partial cleavage stimulation factor domain CSTF2_hinge PF14327.6 CDJ42548.1 - 0.0011 19.3 5.1 0.012 16.1 3.7 3.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 Neur_chan_memb PF02932.16 CDJ42548.1 - 5.6 6.9 5.1 3.3 7.7 1.1 2.4 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ42548.1 - 6.7 6.6 46.6 0.89 9.5 20.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit IPPT PF01715.17 CDJ42549.1 - 1.6e-24 87.0 0.0 2.5e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 IPP transferase PhoH PF02562.16 CDJ42549.1 - 0.0011 18.5 0.1 0.0018 17.8 0.1 1.3 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 CDJ42549.1 - 0.0016 18.4 0.4 0.022 14.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 CDJ42549.1 - 0.0027 18.1 0.2 0.0034 17.8 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 CDJ42549.1 - 0.0038 17.0 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 CDJ42549.1 - 0.0044 17.2 0.2 0.014 15.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CDJ42549.1 - 0.0058 17.0 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 CDJ42549.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 CDJ42549.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase IPT PF01745.16 CDJ42549.1 - 0.018 14.4 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase MeaB PF03308.16 CDJ42549.1 - 0.032 13.2 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 CDJ42549.1 - 0.042 13.8 0.1 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase ParA PF10609.9 CDJ42549.1 - 0.051 13.0 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase NACHT PF05729.12 CDJ42549.1 - 0.051 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 CDJ42549.1 - 0.056 13.4 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 CDJ42549.1 - 0.062 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 CDJ42549.1 - 0.067 12.8 0.5 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NODP PF07684.12 CDJ42549.1 - 0.073 13.2 0.1 0.21 11.7 0.1 1.8 1 0 0 1 1 1 0 NOTCH protein ATPase_2 PF01637.18 CDJ42549.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Spt20 PF12090.8 CDJ42549.1 - 1.5 8.3 19.1 0.16 11.5 1.8 2.4 2 0 0 2 2 2 0 Spt20 family CCDC117 PF15810.5 CDJ42549.1 - 5.9 7.2 9.1 0.18 12.1 1.6 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 117 PH PF00169.29 CDJ42550.1 - 5.7e-05 23.6 0.0 7.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 PH domain Sec3-PIP2_bind PF15277.6 CDJ42550.1 - 0.016 15.3 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH DUF4834 PF16118.5 CDJ42551.1 - 0.37 11.8 0.1 0.37 11.8 0.1 4.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Glyco_transf_7N PF13733.6 CDJ42552.1 - 1.8e-09 37.4 3.2 1.4e-08 34.5 3.2 2.2 1 1 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CDJ42552.1 - 2.4e-07 30.3 0.0 4.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase SUIM_assoc PF16619.5 CDJ42552.1 - 0.075 13.1 12.5 0.81 9.8 3.4 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ42552.1 - 0.56 9.8 6.4 1.4 8.5 6.4 1.6 1 0 0 1 1 1 0 Spt20 family Ras PF00071.22 CDJ42554.1 - 5.2e-44 149.7 0.1 5.9e-44 149.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ42554.1 - 1.3e-32 112.5 0.0 1.6e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ42554.1 - 1.3e-12 47.5 0.0 1.6e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ42554.1 - 4.2e-08 33.3 0.0 5.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ42554.1 - 1.3e-05 24.9 0.0 0.0008 19.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDJ42554.1 - 2.2e-05 23.9 0.0 2.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDJ42554.1 - 0.001 18.6 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 CDJ42554.1 - 0.011 15.1 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 0 Septin TniB PF05621.11 CDJ42554.1 - 0.016 14.6 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 CDJ42554.1 - 0.018 14.9 0.1 0.13 12.1 0.1 2.1 1 1 2 3 3 3 0 RsgA GTPase G-alpha PF00503.20 CDJ42554.1 - 0.067 12.3 0.9 0.18 11.0 0.7 1.7 1 1 1 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 CDJ42554.1 - 0.078 12.5 0.1 0.22 11.1 0.1 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B ATPase_2 PF01637.18 CDJ42554.1 - 0.098 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CDJ42554.1 - 0.1 12.3 0.1 0.15 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CDJ42554.1 - 0.12 12.1 0.1 0.15 11.8 0.1 1.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CDJ42554.1 - 0.12 11.9 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DLIC PF05783.11 CDJ42554.1 - 0.13 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 CDJ42554.1 - 0.21 12.0 0.0 0.29 11.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain SIR2 PF02146.17 CDJ42555.1 - 5.7e-47 159.9 0.0 7.1e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CDJ42555.1 - 2.4e-05 24.1 0.0 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Med16 PF11635.8 CDJ42555.1 - 0.041 11.8 0.0 0.049 11.5 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 PNTB PF02233.16 CDJ42555.1 - 0.14 11.1 0.1 1 8.2 0.0 1.9 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit zf-CSL PF05207.13 CDJ42555.1 - 0.38 10.5 1.3 6.2 6.6 1.3 2.3 1 1 0 1 1 1 0 CSL zinc finger GMC_oxred_C PF05199.13 CDJ42557.1 - 4e-21 76.0 0.1 5.9e-16 59.3 0.0 2.9 3 0 0 3 3 3 2 GMC oxidoreductase GMC_oxred_N PF00732.19 CDJ42557.1 - 3.9e-09 36.3 0.1 6.5e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Phage_integrase PF00589.22 CDJ42558.1 - 0.061 13.1 1.2 0.11 12.2 1.2 1.3 1 0 0 1 1 1 0 Phage integrase family Ndc1_Nup PF09531.10 CDJ42558.1 - 5.9 5.4 7.1 3.7 6.1 2.3 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Ribosomal_L22 PF00237.19 CDJ42559.1 - 2.6e-18 66.1 0.2 3.5e-18 65.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ELFV_dehydrog PF00208.21 CDJ42560.1 - 5.4e-78 262.1 0.9 6.8e-78 261.7 0.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CDJ42560.1 - 2.1e-51 173.2 0.0 7.7e-51 171.4 0.0 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 CDJ42560.1 - 0.0013 19.2 0.2 0.0031 17.9 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding ThiF PF00899.21 CDJ42560.1 - 0.019 14.3 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 ThiF family Bac_GDH PF05088.12 CDJ42560.1 - 0.12 9.8 0.2 0.17 9.3 0.2 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase 2-Hacid_dh_C PF02826.19 CDJ42560.1 - 0.2 11.0 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Josephin PF02099.17 CDJ42561.1 - 3.1e-43 147.7 0.0 2.3e-42 144.9 0.0 2.0 2 0 0 2 2 2 1 Josephin UIM PF02809.20 CDJ42561.1 - 0.02 14.8 0.8 0.054 13.4 0.8 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif S-methyl_trans PF02574.16 CDJ42561.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Homocysteine S-methyltransferase PTS_IIA PF02255.16 CDJ42561.1 - 0.45 10.6 2.9 0.69 10.0 0.1 2.4 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Osmo_CC PF08946.10 CDJ42562.1 - 2.5 8.4 5.6 36 4.7 5.5 2.3 1 1 0 1 1 1 0 Osmosensory transporter coiled coil APC_rep PF18797.1 CDJ42563.1 - 0.1 13.5 2.8 0.8 10.7 1.7 2.3 2 0 0 2 2 2 0 Adenomatous polyposis coli (APC) repeat TFIIA PF03153.13 CDJ42563.1 - 0.21 11.6 14.3 0.25 11.3 14.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ42563.1 - 1 8.0 2.3 1.1 8.0 2.3 1.2 1 0 0 1 1 1 0 Presenilin DUF3689 PF12463.8 CDJ42564.1 - 1.5e-22 80.3 0.1 4.3e-12 46.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3689) SR-25 PF10500.9 CDJ42564.1 - 0.00096 18.8 8.2 0.00096 18.8 8.2 12.9 12 2 2 14 14 14 3 Nuclear RNA-splicing-associated protein ANAPC_CDC26 PF10471.9 CDJ42564.1 - 0.0018 19.1 4.0 0.0018 19.1 4.0 14.5 13 4 1 14 14 14 2 Anaphase-promoting complex APC subunit CDC26 DUF4195 PF13836.6 CDJ42566.1 - 0.32 11.1 17.9 0.76 9.9 17.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4195) DUF4834 PF16118.5 CDJ42567.1 - 0.0018 19.2 1.2 0.39 11.7 0.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) CPSF100_C PF13299.6 CDJ42567.1 - 0.064 13.4 0.9 0.65 10.2 0.2 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal V_ATPase_I PF01496.19 CDJ42567.1 - 0.54 8.1 3.0 0.79 7.6 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ42567.1 - 2.5 6.8 8.2 5.8 5.6 8.2 1.5 1 1 0 1 1 1 0 Presenilin Aerolysin PF01117.20 CDJ42567.1 - 8.3 5.5 6.7 0.36 10.0 0.7 1.6 2 0 0 2 2 2 0 Aerolysin toxin RskA PF10099.9 CDJ42567.1 - 9.8 6.4 27.3 88 3.3 27.3 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA APA3_viroporin PF11289.8 CDJ42569.1 - 0.31 10.5 2.5 0.34 10.4 2.5 1.0 1 0 0 1 1 1 0 Coronavirus accessory protein 3a GLTT PF01744.20 CDJ42570.1 - 0.35 10.7 3.7 0.22 11.3 1.4 1.9 2 0 0 2 2 2 0 GLTT repeat (6 copies) ESM4 PF15952.5 CDJ42572.1 - 0.00074 20.0 13.7 0.0014 19.1 1.3 3.2 3 0 0 3 3 3 1 Enhancer of split M4 family HTH_20 PF12840.7 CDJ42572.1 - 0.077 13.1 3.5 0.28 11.3 3.5 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Spt20 PF12090.8 CDJ42572.1 - 0.09 12.4 29.7 0.032 13.8 13.1 2.4 2 0 0 2 2 2 0 Spt20 family HGTP_anticodon2 PF12745.7 CDJ42572.1 - 1.7 8.1 12.1 0.042 13.3 2.8 2.4 3 0 0 3 3 3 0 Anticodon binding domain of tRNAs DUF4834 PF16118.5 CDJ42572.1 - 1.7 9.7 8.3 1.7 9.6 2.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CCDC53 PF10152.9 CDJ42572.1 - 1.8 8.9 10.4 0.17 12.3 3.4 2.5 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 CDJ42572.1 - 2.6 6.7 6.3 5.2 5.7 6.1 1.4 1 1 0 1 1 1 0 Presenilin Peroxin-13_N PF04088.13 CDJ42572.1 - 9.4 6.5 6.9 1.5 9.1 0.7 2.4 3 0 0 3 3 3 0 Peroxin 13, N-terminal region EPL1 PF10513.9 CDJ42572.1 - 9.6 6.6 11.0 7.1 7.0 5.3 2.3 2 1 0 2 2 2 0 Enhancer of polycomb-like SUIM_assoc PF16619.5 CDJ42573.1 - 0.0056 16.7 2.9 0.018 15.1 2.9 1.9 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ42573.1 - 0.012 15.3 2.2 0.012 15.3 2.2 3.0 2 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF1835 PF08874.10 CDJ42573.1 - 0.024 14.9 0.5 0.1 12.8 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) Spt20 PF12090.8 CDJ42573.1 - 0.3 10.7 5.9 0.57 9.8 5.9 1.4 1 0 0 1 1 1 0 Spt20 family Lin-8 PF03353.15 CDJ42573.1 - 3 7.3 8.2 1.4 8.4 3.9 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Hid1 PF12722.7 CDJ42573.1 - 3.2 5.8 4.4 5.3 5.0 4.4 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YqfQ PF14181.6 CDJ42574.1 - 0.0053 17.0 0.5 0.0058 16.9 0.5 1.3 1 0 0 1 1 1 1 YqfQ-like protein Med3 PF11593.8 CDJ42574.1 - 0.045 12.9 4.6 0.062 12.5 4.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CAP_N PF01213.19 CDJ42574.1 - 0.065 12.7 2.4 0.096 12.1 2.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3306 PF11748.8 CDJ42574.1 - 0.22 12.4 4.1 0.38 11.6 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) E1-E2_ATPase PF00122.20 CDJ42575.1 - 6.5e-27 94.2 6.7 2.2e-15 56.7 0.2 4.4 4 1 0 5 5 5 2 E1-E2 ATPase Hydrolase PF00702.26 CDJ42575.1 - 2.1e-22 80.4 0.9 2.1e-22 80.4 0.9 3.2 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CDJ42575.1 - 2.8e-08 34.1 0.1 5.8e-07 29.9 0.0 2.4 2 0 0 2 2 2 1 Heavy-metal-associated domain DUF5341 PF17276.2 CDJ42575.1 - 0.045 13.9 2.7 0.078 13.1 2.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5341) Tsg PF04668.12 CDJ42575.1 - 0.89 10.2 2.2 1.7 9.3 2.2 1.4 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region Hydrolase_3 PF08282.12 CDJ42575.1 - 0.89 9.2 5.0 2.4 7.8 0.7 2.6 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase ORC_WH_C PF18137.1 CDJ42575.1 - 2.7 8.1 5.9 6.8 6.8 5.9 1.7 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal SDA1 PF05285.12 CDJ42578.1 - 4.8e-44 151.2 32.3 6.2e-44 150.8 32.3 1.1 1 0 0 1 1 1 1 SDA1 Pep1_7 PF17232.2 CDJ42578.1 - 0.033 14.6 0.6 0.033 14.6 0.6 3.7 4 2 0 4 4 4 0 Elicitor peptide 1-7 DUF2981 PF11200.8 CDJ42578.1 - 4.8 6.8 10.4 0.47 10.1 5.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) Cyt-b5 PF00173.28 CDJ42579.1 - 5.9e-17 61.6 0.0 9.5e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TFIIA PF03153.13 CDJ42579.1 - 5.6 6.9 7.8 8.3 6.3 7.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MDMPI_N PF11716.8 CDJ42579.1 - 8.2 7.1 31.1 22 5.7 31.1 1.8 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain LMBR1 PF04791.16 CDJ42580.1 - 0.41 9.5 0.5 0.41 9.5 0.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Coatomer_WDAD PF04053.14 CDJ42581.1 - 1.8e-61 208.5 0.0 2.7e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region PP2C PF00481.21 CDJ42581.1 - 2.4e-51 174.8 0.1 2.5e-47 161.7 0.0 3.4 2 1 1 3 3 3 3 Protein phosphatase 2C SUIM_assoc PF16619.5 CDJ42581.1 - 0.0077 16.3 1.9 0.0077 16.3 1.9 4.8 3 2 2 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 Sec16_C PF12931.7 CDJ42581.1 - 0.017 14.8 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 Apt1 PF10351.9 CDJ42581.1 - 8.5 5.1 13.1 18 4.0 13.1 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF572 PF04502.13 CDJ42582.1 - 0.047 13.3 15.5 0.065 12.9 15.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) V_ATPase_I PF01496.19 CDJ42582.1 - 0.16 9.9 5.3 0.2 9.5 5.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family VIT1 PF01988.19 CDJ42582.1 - 0.39 10.5 7.5 0.03 14.2 2.6 1.7 2 0 0 2 2 2 0 VIT family Glycogen_syn PF05693.13 CDJ42582.1 - 2.5 6.5 5.4 3.7 6.0 5.4 1.2 1 0 0 1 1 1 0 Glycogen synthase TMPIT PF07851.13 CDJ42582.1 - 3.8 6.7 13.9 5.7 6.1 13.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Det1 PF09737.9 CDJ42582.1 - 7.8 5.4 7.9 3 6.8 0.0 2.0 2 0 0 2 2 2 0 De-etiolated protein 1 Det1 CCB2_CCB4 PF11152.8 CDJ42584.1 - 0.0049 16.2 0.9 0.0049 16.2 0.9 1.6 1 1 1 2 2 2 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 TFIIA PF03153.13 CDJ42584.1 - 0.49 10.3 9.6 0.6 10.0 9.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIA PF03153.13 CDJ42585.1 - 1.1e-07 32.3 31.6 2.2e-07 31.2 31.6 1.6 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ42585.1 - 2.1e-05 24.8 3.2 0.00013 22.2 3.4 2.1 2 0 0 2 2 2 1 DDHD domain PhoD PF09423.10 CDJ42585.1 - 2.2e-05 23.6 2.0 2.2e-05 23.6 2.0 4.1 1 1 1 2 2 1 1 PhoD-like phosphatase GAGA_bind PF06217.12 CDJ42585.1 - 0.001 19.5 5.6 0.0015 18.9 5.6 1.3 1 0 0 1 1 1 1 GAGA binding protein-like family SAPS PF04499.15 CDJ42585.1 - 0.0013 17.6 3.9 0.002 17.0 3.9 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 CDJ42585.1 - 0.0044 16.9 17.4 0.0078 16.1 17.4 1.4 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Myc_N PF01056.18 CDJ42585.1 - 0.0053 16.7 4.2 0.0053 16.7 4.2 2.4 3 0 0 3 3 3 1 Myc amino-terminal region CDC45 PF02724.14 CDJ42585.1 - 0.0061 14.9 14.1 0.011 14.0 14.1 1.4 1 0 0 1 1 1 1 CDC45-like protein SpoIIP PF07454.11 CDJ42585.1 - 0.011 15.3 17.6 0.019 14.5 17.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ42585.1 - 0.011 14.8 22.1 0.018 14.0 22.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CCSAP PF15748.5 CDJ42585.1 - 0.014 15.6 19.6 0.014 15.6 19.6 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated CBP_BcsF PF11120.8 CDJ42585.1 - 0.024 14.8 9.2 0.059 13.5 9.2 1.7 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF Mem_trans PF03547.18 CDJ42585.1 - 0.033 12.6 0.1 0.063 11.7 0.1 1.4 1 0 0 1 1 1 0 Membrane transport protein Band_3_cyto PF07565.13 CDJ42585.1 - 0.047 13.5 11.6 0.098 12.5 11.6 1.6 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PTPRCAP PF15713.5 CDJ42585.1 - 0.069 13.4 22.7 0.21 11.9 22.7 1.8 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SID-1_RNA_chan PF13965.6 CDJ42585.1 - 0.081 11.3 2.6 0.12 10.8 2.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2052 PF09747.9 CDJ42585.1 - 0.092 12.9 20.6 0.61 10.2 19.7 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) EBP50_C PF09007.11 CDJ42585.1 - 0.11 13.5 23.2 0.22 12.5 12.8 2.4 2 0 0 2 2 2 0 EBP50, C-terminal Tim54 PF11711.8 CDJ42585.1 - 0.14 10.9 17.9 0.25 10.1 17.9 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S49_N PF08496.10 CDJ42585.1 - 0.14 12.2 10.7 0.43 10.6 10.7 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Endostatin PF06482.11 CDJ42585.1 - 0.2 11.1 17.8 0.42 10.0 17.8 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin EMC3_TMCO1 PF01956.16 CDJ42585.1 - 0.25 11.1 6.8 0.46 10.2 6.8 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PepSY_TM PF03929.16 CDJ42585.1 - 0.31 10.7 12.7 0.43 10.2 7.1 3.1 3 0 0 3 3 3 0 PepSY-associated TM region Hid1 PF12722.7 CDJ42585.1 - 0.32 9.1 16.5 0.5 8.4 16.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCDC53 PF10152.9 CDJ42585.1 - 0.45 10.9 24.5 1.8 9.0 23.4 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Ureide_permease PF07168.11 CDJ42585.1 - 0.53 9.0 6.9 1.4 7.6 6.3 1.9 2 0 0 2 2 2 0 Ureide permease Otopetrin PF03189.13 CDJ42585.1 - 0.57 8.9 6.0 0.87 8.3 6.0 1.2 1 0 0 1 1 1 0 Otopetrin PIP5K PF01504.18 CDJ42585.1 - 0.61 9.3 14.0 1.1 8.4 14.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase TCP PF03634.13 CDJ42585.1 - 0.64 10.6 21.2 0.036 14.6 13.8 2.2 2 0 0 2 2 2 0 TCP family transcription factor BORG_CEP PF14957.6 CDJ42585.1 - 0.75 11.0 18.2 0.4 11.8 13.6 2.3 2 0 0 2 2 2 0 Cdc42 effector PAT1 PF09770.9 CDJ42585.1 - 0.97 7.6 38.2 1.5 7.0 38.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ALMT PF11744.8 CDJ42585.1 - 1.2 7.9 14.8 1.9 7.2 14.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2126 PF09899.9 CDJ42585.1 - 1.4 6.9 15.2 2 6.4 15.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Presenilin PF01080.17 CDJ42585.1 - 1.5 7.5 31.3 0.69 8.6 28.3 1.7 2 0 0 2 2 2 0 Presenilin Cellulose_synt PF03552.14 CDJ42585.1 - 1.9 6.9 4.0 2.7 6.4 4.0 1.3 1 0 0 1 1 1 0 Cellulose synthase Afi1 PF07792.12 CDJ42585.1 - 2.2 8.7 19.4 4.8 7.7 19.4 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Zip PF02535.22 CDJ42585.1 - 2.5 7.2 10.2 5.7 6.0 10.2 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.15 CDJ42585.1 - 3 6.7 10.3 6 5.7 10.3 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pex14_N PF04695.13 CDJ42585.1 - 3 8.5 42.2 1.3 9.7 34.7 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.16 CDJ42585.1 - 3 7.8 19.0 1.5 8.8 16.1 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 CDJ42585.1 - 5.8 5.5 18.9 0.33 9.6 13.1 1.9 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup SLC12 PF03522.15 CDJ42585.1 - 6.2 5.7 23.8 11 5.0 23.8 1.3 1 0 0 1 1 1 0 Solute carrier family 12 CSG2 PF16965.5 CDJ42585.1 - 7 5.5 13.0 70 2.2 12.4 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator FAP206 PF12018.8 CDJ42586.1 - 1.1e-10 41.6 1.5 1.1e-10 41.6 1.5 2.3 2 1 0 2 2 2 1 Domain of unknown function Proteasome PF00227.26 CDJ42587.1 - 3.9e-27 95.0 0.1 3.5e-13 49.5 0.0 2.7 2 1 0 2 2 2 2 Proteasome subunit DUF4034 PF13226.6 CDJ42587.1 - 0.011 15.1 0.1 0.011 15.1 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4034) DUF5336 PF17270.2 CDJ42587.1 - 0.032 13.9 0.3 0.032 13.9 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5336) PIP5K PF01504.18 CDJ42587.1 - 0.042 13.1 0.2 0.065 12.5 0.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase TFIIA PF03153.13 CDJ42587.1 - 0.084 12.9 8.0 0.17 11.9 8.1 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit COX17 PF05051.13 CDJ42588.1 - 0.08 13.3 1.7 3 8.3 1.8 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Mlh1_C PF16413.5 CDJ42589.1 - 1.8e-40 139.0 0.0 1.8e-40 139.0 0.0 2.6 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CDJ42589.1 - 3.2e-26 91.4 0.0 6.2e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CDJ42589.1 - 2.9e-08 33.6 0.0 8.9e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ42589.1 - 0.0002 21.9 0.0 0.00079 19.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEAT PF02985.22 CDJ42591.1 - 4.4e-08 32.7 10.5 0.009 16.2 0.2 6.8 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 CDJ42591.1 - 4.8e-05 23.7 9.7 0.042 14.2 0.0 5.8 5 2 2 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 CDJ42591.1 - 0.017 15.6 4.8 13 6.4 1.1 4.5 3 1 0 3 3 3 0 HEAT-like repeat DnaJ_C PF01556.18 CDJ42592.1 - 4.9e-38 130.5 0.1 6.9e-38 130.1 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDJ42592.1 - 5.3e-23 80.9 1.9 9.2e-23 80.2 1.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CDJ42592.1 - 7.1e-13 48.7 16.3 7.1e-13 48.7 16.3 2.3 2 0 0 2 2 2 1 DnaJ central domain Tnp_zf-ribbon_2 PF13842.6 CDJ42592.1 - 0.19 12.6 10.5 1.1 10.1 0.1 3.5 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon HypA PF01155.19 CDJ42592.1 - 0.46 10.5 10.8 1.8 8.6 0.5 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RRM_1 PF00076.22 CDJ42593.1 - 1.9e-10 40.4 0.0 3.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ42593.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif V-SNARE_C PF12352.8 CDJ42594.1 - 1.3e-13 51.0 0.1 2.9e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CDJ42594.1 - 0.0061 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Sec20 AA_permease_2 PF13520.6 CDJ42594.1 - 0.11 11.3 0.5 0.15 10.9 0.5 1.1 1 0 0 1 1 1 0 Amino acid permease Peptidase_S8 PF00082.22 CDJ42595.1 - 1.9e-43 148.9 0.1 3.3e-43 148.1 0.1 1.3 1 0 0 1 1 1 1 Subtilase family EGF_CA PF07645.15 CDJ42595.1 - 3.2e-14 52.9 42.9 3.7e-09 36.6 5.9 4.6 3 1 1 4 4 3 3 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ42595.1 - 6.7e-13 48.6 41.7 7.6e-05 22.8 10.6 4.4 4 0 0 4 4 4 4 EGF domain cEGF PF12662.7 CDJ42595.1 - 3.1e-10 39.8 14.0 4.4e-05 23.3 1.6 3.6 3 0 0 3 3 3 2 Complement Clr-like EGF-like S_locus_glycop PF00954.20 CDJ42595.1 - 0.0041 17.6 27.4 0.04 14.5 2.0 3.7 3 0 0 3 3 3 2 S-locus glycoprotein domain Cu-binding_MopE PF11617.8 CDJ42595.1 - 0.1 12.8 2.7 0.28 11.4 2.7 1.8 1 0 0 1 1 1 0 Putative metal-binding motif Plasmod_Pvs28 PF06247.11 CDJ42595.1 - 0.14 12.4 32.6 0.16 12.3 6.6 5.1 4 1 1 5 5 5 0 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 CDJ42595.1 - 0.16 12.1 40.5 0.057 13.5 5.1 4.6 4 0 0 4 4 4 0 MSP1 EGF domain 1 EGF PF00008.27 CDJ42595.1 - 0.16 12.3 39.6 0.084 13.2 2.9 4.6 4 0 0 4 4 4 0 EGF-like domain FXa_inhibition PF14670.6 CDJ42595.1 - 2.4 8.5 41.2 0.39 11.0 4.0 4.4 4 0 0 4 4 4 0 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CDJ42595.1 - 3 8.6 35.8 0.26 12.0 3.8 5.0 4 1 0 4 4 4 0 Human growth factor-like EGF Peptidase_C50 PF03568.17 CDJ42600.1 - 1.1e-05 24.8 0.1 1.5e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C50 SF-assemblin PF06705.11 CDJ42601.1 - 1.4e-30 106.5 20.0 1.1e-28 100.2 17.3 2.1 2 0 0 2 2 2 2 SF-assemblin/beta giardin Ribosomal_L17 PF01196.19 CDJ42601.1 - 2.6e-10 41.0 1.1 1e-09 39.1 0.1 2.4 2 0 0 2 2 2 1 Ribosomal protein L17 Baculo_PEP_C PF04513.12 CDJ42601.1 - 1.5 8.9 7.4 0.58 10.2 0.2 3.0 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus betaPIX_CC PF16523.5 CDJ42601.1 - 8.7 6.2 10.0 3.1 7.7 0.1 2.9 3 0 0 3 3 3 0 betaPIX coiled coil FBPase PF00316.20 CDJ42603.1 - 1.7e-33 115.7 0.0 2.9e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 CDJ42603.1 - 0.045 13.3 0.0 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 Inositol monophosphatase family Peptidase_M24 PF00557.24 CDJ42604.1 - 1.1e-56 191.8 0.0 1.9e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CDJ42604.1 - 1.7e-13 50.4 0.0 3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3376 PF11856.8 CDJ42604.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) Ank_2 PF12796.7 CDJ42606.1 - 1.3e-05 25.7 0.0 1.7e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ42606.1 - 0.004 17.5 0.0 0.31 11.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 CDJ42606.1 - 0.0061 17.1 0.0 0.0094 16.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CDJ42606.1 - 0.0074 16.7 0.0 5.3 7.7 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CDJ42606.1 - 0.023 15.0 0.1 0.07 13.5 0.1 1.8 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Kinesin PF00225.23 CDJ42608.1 - 8.2e-10 38.1 0.0 9.3e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Peptidase_C48 PF02902.19 CDJ42610.1 - 7.9e-11 42.2 3.3 4.5e-10 39.8 3.3 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SNF2_N PF00176.23 CDJ42612.1 - 1.9e-68 230.7 0.0 3e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_5 PF14634.6 CDJ42612.1 - 1.3e-07 31.4 5.5 3.9e-07 29.9 5.5 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDJ42612.1 - 2.3e-06 27.3 5.5 6.2e-06 26.0 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ42612.1 - 2.8e-05 23.9 6.7 7.5e-05 22.5 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ42612.1 - 0.00087 19.1 8.2 0.0025 17.6 8.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ42612.1 - 0.0031 17.8 8.3 0.0089 16.3 8.3 1.9 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.31 CDJ42612.1 - 0.0041 17.5 0.0 0.22 11.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.6 CDJ42612.1 - 0.015 15.4 8.5 0.041 14.0 8.5 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CDJ42612.1 - 0.02 14.7 8.7 0.095 12.6 8.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CDJ42612.1 - 0.032 14.3 6.1 0.082 12.9 6.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 CDJ42612.1 - 0.14 12.1 2.3 0.35 10.8 2.3 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_5 PF17121.5 CDJ42612.1 - 0.29 11.0 7.9 0.75 9.7 6.6 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ42612.1 - 1.5 9.2 5.2 5.5 7.4 5.2 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CDJ42612.1 - 2.3 8.1 4.2 18 5.3 4.7 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Pkinase_Tyr PF07714.17 CDJ42613.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ42613.1 - 0.032 13.6 0.0 0.092 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain Etmic-2 PF06670.11 CDJ42616.1 - 4e-224 743.6 30.3 1.5e-222 738.4 30.3 2.0 1 1 0 1 1 1 1 Microneme protein Etmic-2 TBPIP PF07106.13 CDJ42619.1 - 5.2e-16 58.3 0.1 1.2e-15 57.2 0.0 1.6 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 CDJ42619.1 - 0.026 14.6 0.0 0.074 13.2 0.0 1.8 1 0 0 1 1 1 0 Leucine zipper with capping helix domain TF_AP-2 PF03299.14 CDJ42619.1 - 0.041 13.9 2.1 0.064 13.2 2.1 1.2 1 0 0 1 1 1 0 Transcription factor AP-2 FANCAA PF15146.6 CDJ42619.1 - 0.15 11.1 6.6 0.36 9.9 6.5 1.6 1 1 1 2 2 2 0 Fanconi anemia-associated LapA_dom PF06305.11 CDJ42620.1 - 0.0013 18.4 3.4 0.0019 18.0 0.7 2.2 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain Sensor PF13796.6 CDJ42620.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative sensor Sin3a_C PF16879.5 CDJ42620.1 - 0.085 12.6 0.4 0.085 12.6 0.4 1.6 2 0 0 2 2 2 0 C-terminal domain of Sin3a protein TT_ORF2 PF02957.15 CDJ42620.1 - 0.21 12.5 4.1 4.1 8.3 1.6 2.2 2 0 0 2 2 2 0 TT viral ORF2 MscS_TM PF12794.7 CDJ42620.1 - 0.85 8.4 6.6 0.12 11.2 1.2 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 WASH-7_C PF14746.6 CDJ42620.1 - 1.2 8.8 3.9 0.38 10.4 0.4 1.8 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal eIF-3_zeta PF05091.12 CDJ42620.1 - 2.9 6.8 6.3 1.7 7.6 3.5 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CFIA_Pcf11 PF11526.8 CDJ42620.1 - 5.7 7.5 14.2 0.71 10.4 0.5 2.9 3 0 0 3 3 3 0 Subunit of cleavage factor IA Pcf11 ANAPC_CDC26 PF10471.9 CDJ42620.1 - 8.8 7.2 29.6 0.12 13.2 8.8 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 DUF4834 PF16118.5 CDJ42620.1 - 9.8 7.2 14.9 1.1 10.3 1.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) RRM_1 PF00076.22 CDJ42621.1 - 2.2e-08 33.8 0.0 3.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AP-5_subunit_s1 PF15001.6 CDJ42622.1 - 2.8e-19 69.9 0.2 2.3e-18 66.9 0.2 2.1 1 1 0 1 1 1 1 AP-5 complex subunit sigma-1 Pentapeptide_4 PF13599.6 CDJ42623.1 - 0.31 11.2 16.2 0.96 9.7 3.8 2.5 1 1 2 3 3 3 0 Pentapeptide repeats (9 copies) MIF4G_like PF09088.11 CDJ42623.1 - 7.8 6.2 10.4 6.9 6.4 2.3 2.3 1 1 1 2 2 2 0 MIF4G like RAP PF08373.10 CDJ42624.1 - 2.3e-06 27.6 0.1 5.8e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 RAP domain DUF559 PF04480.12 CDJ42624.1 - 0.002 18.0 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF559) LcrG PF07216.12 CDJ42624.1 - 0.49 10.4 5.1 2.7 8.0 0.4 3.3 3 0 0 3 3 3 0 LcrG protein MCM_bind PF09739.9 CDJ42625.1 - 6.4e-26 90.9 30.7 1.1e-09 37.3 2.2 7.4 4 2 2 7 7 7 5 Mini-chromosome maintenance replisome factor AAA_23 PF13476.6 CDJ42625.1 - 0.002 18.6 7.2 0.002 18.6 7.2 4.1 4 0 0 4 4 4 2 AAA domain DUF4667 PF15700.5 CDJ42625.1 - 0.0028 17.8 5.1 0.0028 17.8 5.1 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4667) Herpes_IE2_3 PF03361.14 CDJ42625.1 - 0.0052 16.7 0.9 0.014 15.3 0.9 1.7 1 0 0 1 1 1 1 Herpes virus intermediate/early protein 2/3 Sporozoite_P67 PF05642.11 CDJ42625.1 - 0.27 9.3 9.6 0.21 9.7 6.3 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PT-TG PF14449.6 CDJ42625.1 - 0.31 11.0 0.1 0.31 11.0 0.1 2.1 2 0 0 2 2 2 0 Pre-toxin TG Methyltransf_23 PF13489.6 CDJ42625.1 - 0.43 10.4 5.6 3 7.7 0.0 3.3 3 0 0 3 3 3 0 Methyltransferase domain Med15 PF09606.10 CDJ42625.1 - 0.8 8.3 44.3 0.79 8.3 4.9 3.3 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Init_tRNA_PT PF04179.12 CDJ42625.1 - 1.5 9.2 4.9 0.49 10.7 0.4 2.6 2 0 0 2 2 2 0 Rit1 DUSP-like domain Pex14_N PF04695.13 CDJ42625.1 - 8.2 7.1 39.9 0.034 14.8 5.6 5.3 4 1 1 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NTF2 PF02136.20 CDJ42626.1 - 9.5e-25 87.5 0.0 1.3e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 CDJ42626.1 - 0.039 13.9 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 DUF4518 PF15008.6 CDJ42626.1 - 0.22 10.7 0.0 0.3 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Octopine_DH PF02317.17 CDJ42627.1 - 3.8e-37 127.7 0.0 5.4e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain PDH PF02153.17 CDJ42627.1 - 0.0016 17.5 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.23 CDJ42627.1 - 0.0021 18.1 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 CDJ42627.1 - 0.0024 18.4 0.0 0.0073 16.9 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 CDJ42627.1 - 0.071 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 CDJ42627.1 - 0.091 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 CDJ42627.1 - 0.38 11.3 1.3 1.5 9.4 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AhpC-TSA PF00578.21 CDJ42629.1 - 1.5e-29 102.4 0.0 1.9e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ42629.1 - 6.1e-13 48.7 0.0 7.7e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDJ42629.1 - 1.9e-07 30.8 0.1 3.2e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 CDJ42629.1 - 0.0085 16.2 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme TENA_THI-4 PF03070.16 CDJ42629.1 - 0.2 11.5 0.0 0.38 10.5 0.0 1.5 2 0 0 2 2 2 0 TENA/THI-4/PQQC family CwfJ_C_1 PF04677.15 CDJ42630.1 - 6.9e-25 87.3 0.0 1.1e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CDJ42630.1 - 2.6e-07 31.4 0.0 1e-06 29.5 0.0 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 RRM_1 PF00076.22 CDJ42630.1 - 3.1e-07 30.1 0.0 5.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sin_N PF04801.13 CDJ42630.1 - 0.12 11.6 1.9 0.18 11.0 1.9 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Spt20 PF12090.8 CDJ42631.1 - 0.00036 20.2 6.3 0.00036 20.2 6.3 2.5 3 0 0 3 3 3 1 Spt20 family Presenilin PF01080.17 CDJ42631.1 - 2 7.1 9.1 0.15 10.8 2.2 2.0 2 0 0 2 2 2 0 Presenilin EF-hand_1 PF00036.32 CDJ42632.1 - 1.6e-40 133.6 10.2 1.2e-09 37.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ42632.1 - 7.6e-35 119.2 1.9 5.3e-17 62.0 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ42632.1 - 1e-32 111.8 10.5 8.2e-16 57.6 0.6 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CDJ42632.1 - 7.1e-29 97.2 6.0 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDJ42632.1 - 4.9e-26 89.0 8.6 2.3e-06 26.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CDJ42632.1 - 4.3e-15 55.8 0.1 3.3e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDJ42632.1 - 2.3e-09 37.1 0.3 0.00039 20.3 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ42632.1 - 1.5e-07 31.7 0.1 0.017 15.4 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CDJ42632.1 - 3.3e-06 27.9 0.0 0.0009 20.1 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CDJ42632.1 - 2.8e-05 24.0 0.0 0.042 13.9 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 CDJ42632.1 - 0.00082 19.5 4.3 0.16 12.2 0.5 2.8 2 2 1 3 3 3 2 Dockerin type I domain Caleosin PF05042.13 CDJ42632.1 - 0.0017 18.3 0.2 0.52 10.2 0.0 3.1 1 1 2 3 3 3 1 Caleosin related protein DUF3349 PF11829.8 CDJ42632.1 - 0.0018 19.0 0.5 1.2 10.0 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) RNA_pol_Rpb4 PF03874.16 CDJ42632.1 - 0.0033 17.7 0.4 1.8 8.9 0.2 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF1103 PF06513.11 CDJ42632.1 - 0.0056 16.3 1.2 0.0067 16.1 1.2 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) EFhand_Ca_insen PF08726.10 CDJ42632.1 - 0.0068 16.5 0.4 0.042 13.9 0.0 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand YqeY PF09424.10 CDJ42632.1 - 0.012 15.6 0.2 0.15 12.1 0.1 2.0 1 1 1 2 2 2 0 Yqey-like protein SurA_N_2 PF13623.6 CDJ42632.1 - 0.015 15.1 0.4 0.85 9.5 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF853 PF05872.12 CDJ42632.1 - 0.026 13.2 0.2 0.7 8.4 0.1 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) EF-hand_14 PF17959.1 CDJ42632.1 - 0.035 14.4 0.1 9.2 6.7 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 CDJ42632.1 - 0.047 13.9 0.1 9.3 6.6 0.0 3.1 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein DUF5580 PF17743.1 CDJ42632.1 - 0.071 11.6 0.0 0.071 11.6 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Fe_hyd_lg_C PF02906.14 CDJ42632.1 - 0.072 12.7 0.6 0.23 11.1 0.6 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain TetR_C_7 PF14246.6 CDJ42632.1 - 0.095 12.7 0.0 6.3 6.9 0.0 2.3 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain SurA_N_3 PF13624.6 CDJ42632.1 - 0.1 12.4 0.2 0.44 10.3 0.0 1.9 1 1 1 2 2 2 0 SurA N-terminal domain dCache_2 PF08269.11 CDJ42632.1 - 0.1 11.7 0.0 7.7 5.6 0.0 2.1 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 CDJ42632.1 - 0.12 12.6 0.4 2 8.6 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain Ribosomal_S10 PF00338.22 CDJ42633.1 - 7.5e-26 90.2 0.1 8.7e-26 90.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF1922 PF09082.10 CDJ42633.1 - 0.02 15.2 0.1 0.048 14.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1922) Ribosomal_L35Ae PF01247.18 CDJ42634.1 - 3.1e-44 149.1 0.4 3.8e-44 148.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CDJ42634.1 - 0.056 13.7 0.1 5.3 7.3 0.0 2.3 2 0 0 2 2 2 0 RimM N-terminal domain OMPdecase PF00215.24 CDJ42635.1 - 7e-24 84.7 0.0 2.6e-23 82.8 0.0 1.7 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.14 CDJ42635.1 - 0.028 13.7 0.0 4.4 6.5 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG HEAT PF02985.22 CDJ42636.1 - 4.4e-10 38.9 24.2 0.06 13.6 0.0 9.9 9 1 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.6 CDJ42636.1 - 4.8e-06 26.9 0.8 4.8e-06 26.9 0.8 9.1 9 1 0 9 9 9 1 HEAT-like repeat IBN_N PF03810.19 CDJ42636.1 - 0.00073 19.4 0.8 0.0052 16.7 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 CDJ42636.1 - 0.0025 18.2 27.5 0.033 14.6 1.2 8.1 6 3 1 7 7 7 3 HEAT repeats Cohesin_HEAT PF12765.7 CDJ42636.1 - 0.74 10.2 8.4 19 5.7 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DUF898 PF05987.13 CDJ42637.1 - 0.087 11.9 0.1 0.19 10.7 0.1 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) PP-binding_2 PF14573.6 CDJ42638.1 - 4.6e-22 78.0 0.1 7.8e-22 77.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier PP-binding PF00550.25 CDJ42638.1 - 0.061 13.7 0.1 0.17 12.2 0.0 1.8 2 0 0 2 2 2 0 Phosphopantetheine attachment site Hydrolase_4 PF12146.8 CDJ42639.1 - 6.3e-20 71.5 0.0 8.1e-08 31.8 0.0 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDJ42639.1 - 4.6e-08 33.9 0.0 6.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CDJ42639.1 - 7e-08 32.2 0.0 7.1e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ42639.1 - 6.3e-06 26.0 0.5 0.0011 18.6 0.5 2.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 CDJ42639.1 - 7.2e-06 24.9 0.1 0.00031 19.5 0.0 2.4 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 CDJ42639.1 - 5.6e-05 22.8 0.0 0.00027 20.6 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 CDJ42639.1 - 0.0007 19.5 0.2 0.026 14.4 0.1 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peroxin-13_N PF04088.13 CDJ42639.1 - 0.0013 19.0 0.1 0.98 9.7 0.0 2.2 2 0 0 2 2 2 2 Peroxin 13, N-terminal region Peptidase_S15 PF02129.18 CDJ42639.1 - 0.005 16.5 0.1 4.3 6.9 0.0 2.8 1 1 2 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 CDJ42639.1 - 0.005 16.6 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 CDJ42639.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 CDJ42639.1 - 0.04 14.0 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 CDJ42639.1 - 0.043 13.7 0.5 0.081 12.8 0.5 1.6 1 1 0 1 1 1 0 Lipase (class 3) Macoilin PF09726.9 CDJ42639.1 - 0.088 11.4 3.2 0.1 11.1 3.2 1.1 1 0 0 1 1 1 0 Macoilin family FSH1 PF03959.13 CDJ42639.1 - 0.093 12.4 0.3 0.46 10.1 0.3 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) RAP1 PF07218.11 CDJ42639.1 - 1.6 6.9 6.3 1.9 6.7 6.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PEPCK_ATP PF01293.20 CDJ42640.1 - 1.8e-143 478.6 6.0 8.1e-94 314.9 0.0 5.1 1 1 4 5 5 5 5 Phosphoenolpyruvate carboxykinase Shadoo PF14999.6 CDJ42640.1 - 0.0093 16.1 5.0 0.02 15.0 5.0 1.5 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective AAA_25 PF13481.6 CDJ42640.1 - 0.0096 15.5 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDJ42640.1 - 0.014 15.6 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.9 CDJ42640.1 - 0.029 14.0 11.7 0.042 13.5 11.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_18 PF13238.6 CDJ42640.1 - 0.083 13.4 0.2 0.78 10.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 CDJ42640.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 CDJ42640.1 - 0.11 12.2 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CDJ42640.1 - 0.14 12.4 0.3 0.4 10.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 CDJ42640.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PEPCK_ATP PF01293.20 CDJ42641.1 - 1.7e-23 83.1 0.0 2e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Activator_LAG-3 PF11498.8 CDJ42642.1 - 0.021 13.8 27.2 0.02 13.9 27.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 NPR1_interact PF15699.5 CDJ42642.1 - 0.046 14.4 1.9 0.064 13.9 1.9 1.2 1 0 0 1 1 1 0 NPR1 interacting EutA PF06277.11 CDJ42642.1 - 0.066 12.1 0.2 0.068 12.0 0.2 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA EIF4E-T PF10477.9 CDJ42642.1 - 0.26 10.0 11.8 0.24 10.2 11.8 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Ribosomal_L12_N PF16320.5 CDJ42642.1 - 0.27 10.9 2.1 0.48 10.2 2.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain TFIIA PF03153.13 CDJ42642.1 - 2.3 8.1 19.2 2.3 8.1 19.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S5 PF00333.20 CDJ42645.1 - 2.5e-14 53.0 0.4 6.3e-14 51.7 0.4 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain PRP38 PF03371.15 CDJ42646.1 - 8.9e-52 175.5 0.2 1.4e-51 174.8 0.2 1.3 1 0 0 1 1 1 1 PRP38 family RMI2 PF16100.5 CDJ42646.1 - 0.018 14.9 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 0 RecQ-mediated genome instability protein 2 PCB_OB PF17092.5 CDJ42646.1 - 0.027 15.2 4.4 0.086 13.6 0.0 3.5 3 1 1 4 4 4 0 Penicillin-binding protein OB-like domain S1 PF00575.23 CDJ42646.1 - 0.04 14.2 0.0 0.18 12.1 0.0 2.2 2 1 0 2 2 2 0 S1 RNA binding domain DUF4551 PF15087.6 CDJ42646.1 - 5.7 5.6 14.9 9.5 4.9 14.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) IMCp PF12314.8 CDJ42647.1 - 1.2e-16 60.7 59.6 3.6e-12 46.4 27.5 5.6 1 1 4 5 5 5 4 Inner membrane complex protein Plasmodium_Vir PF05795.11 CDJ42648.1 - 0.041 13.3 0.4 0.041 13.3 0.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pacs-1 PF10254.9 CDJ42648.1 - 0.39 9.6 2.5 0.5 9.3 2.5 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein SPX PF03105.19 CDJ42648.1 - 0.63 9.9 11.0 0.73 9.7 11.0 1.0 1 0 0 1 1 1 0 SPX domain DUF1180 PF06679.12 CDJ42648.1 - 1.1 9.6 12.4 1.6 9.1 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SpoIIIAH PF12685.7 CDJ42648.1 - 1.3 8.8 10.8 1.7 8.4 10.8 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Presenilin PF01080.17 CDJ42648.1 - 1.7 7.3 4.5 2 7.1 4.5 1.1 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CDJ42648.1 - 2.4 7.7 26.0 3.7 7.1 26.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ42648.1 - 3.2 6.5 11.8 3.9 6.2 11.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain BAF1_ABF1 PF04684.13 CDJ42648.1 - 4.5 6.2 9.4 5.8 5.8 9.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor InvH PF04741.12 CDJ42648.1 - 5.1 7.0 9.0 8.2 6.4 9.0 1.4 1 0 0 1 1 1 0 InvH outer membrane lipoprotein FUSC-like PF12805.7 CDJ42650.1 - 0.021 13.9 16.3 0.023 13.8 15.8 1.3 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS Exonuc_VII_L PF02601.15 CDJ42650.1 - 0.032 13.8 4.6 0.031 13.9 4.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CemA PF03040.14 CDJ42650.1 - 2.3 8.1 5.5 3.1 7.7 5.5 1.2 1 0 0 1 1 1 0 CemA family Herpes_pp85 PF04637.12 CDJ42651.1 - 0.11 10.8 8.8 0.19 10.1 8.8 1.5 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) IL5 PF02025.15 CDJ42651.1 - 0.22 11.8 1.0 0.5 10.7 1.0 1.6 1 0 0 1 1 1 0 Interleukin 5 DcrB PF08786.11 CDJ42651.1 - 2.8 8.1 9.6 0.13 12.4 0.7 3.0 2 1 1 3 3 3 0 DcrB Spore_III_AB PF09548.10 CDJ42651.1 - 5.8 7.0 15.2 3.2 7.9 0.4 2.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) HECT PF00632.25 CDJ42652.1 - 1e-05 25.2 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CDJ42652.1 - 5.3e-05 23.3 0.0 0.00047 20.3 0.0 2.8 2 0 0 2 2 2 1 SPRY domain TRAM_LAG1_CLN8 PF03798.16 CDJ42653.1 - 6.8e-07 29.2 0.6 6.8e-07 29.2 0.6 2.5 2 0 0 2 2 2 2 TLC domain HA2 PF04408.23 CDJ42654.1 - 3.1e-10 40.3 0.0 3.1e-10 40.3 0.0 4.4 4 1 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDJ42654.1 - 2.3e-09 37.6 0.0 1.7e-08 34.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ42654.1 - 0.022 15.0 0.1 3.7 7.8 0.0 3.1 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.9 CDJ42654.1 - 6.2 5.3 26.5 0.12 10.9 15.7 2.6 2 0 0 2 2 2 0 Macoilin family HSP90 PF00183.18 CDJ42655.1 - 4.2e-107 359.2 0.0 2.3e-102 343.6 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CDJ42655.1 - 7.6e-10 38.7 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ42655.1 - 7e-09 36.2 0.1 1.5e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2183 PF09949.9 CDJ42655.1 - 0.01 16.1 0.1 5.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) Methyltransf_15 PF09445.10 CDJ42656.1 - 3.6e-19 68.9 0.0 6.8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase K_channel_TID PF07941.11 CDJ42657.1 - 0.048 14.1 2.6 0.048 14.1 2.6 4.4 3 1 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Ribosomal_60s PF00428.19 CDJ42657.1 - 0.1 13.2 23.2 0.14 12.7 7.5 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2722 PF10846.8 CDJ42657.1 - 0.9 8.4 12.2 1.3 7.9 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DRY_EERY PF09750.9 CDJ42658.1 - 0.017 15.4 2.1 0.051 13.8 2.1 1.9 1 0 0 1 1 1 0 Alternative splicing regulator Secretin_N_2 PF07655.13 CDJ42658.1 - 0.25 11.9 20.7 0.16 12.5 8.8 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain DUF5320 PF17253.2 CDJ42658.1 - 1.3 10.1 6.2 11 7.2 1.1 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5320) DUF2339 PF10101.9 CDJ42659.1 - 0.17 10.4 5.4 0.24 9.9 5.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) SUIM_assoc PF16619.5 CDJ42659.1 - 0.42 10.7 0.0 0.42 10.7 0.0 6.7 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 CcmF_C PF16327.5 CDJ42659.1 - 0.45 9.7 4.3 0.75 9.0 4.3 1.4 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal DUF3292 PF11696.8 CDJ42659.1 - 2.1 6.6 25.7 0.024 13.0 15.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) Peptidase_S15 PF02129.18 CDJ42659.1 - 6 6.4 22.8 10 5.6 22.8 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PMSI1 PF15322.6 CDJ42659.1 - 6.9 6.0 32.8 0.58 9.6 26.3 2.1 2 1 0 2 2 2 0 Protein missing in infertile sperm 1, putative DUF2368 PF10166.9 CDJ42660.1 - 0.01 15.5 3.3 0.012 15.2 3.3 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) TRAPPC10 PF12584.8 CDJ42661.1 - 0.0011 18.6 0.0 0.0033 17.1 0.0 1.8 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Ribosomal_L30_N PF08079.12 CDJ42662.1 - 0.4 11.0 17.9 0.93 9.8 17.5 1.7 1 1 1 2 2 2 0 Ribosomal L30 N-terminal domain TRM PF02005.16 CDJ42663.1 - 3.9e-96 322.5 0.0 5.9e-72 242.9 0.0 2.7 2 1 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 CDJ42663.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Tau95 PF09734.9 CDJ42665.1 - 1.2e-26 94.1 2.0 2.9e-23 83.2 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CDJ42665.1 - 0.01 16.0 1.5 0.91 9.7 0.0 3.2 2 1 0 2 2 2 0 Tau95 Triple barrel domain GDI PF00996.18 CDJ42666.1 - 2.7e-14 52.6 0.0 3e-07 29.3 0.0 3.3 3 0 0 3 3 3 3 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CDJ42666.1 - 0.011 15.9 0.0 0.035 14.3 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SUIM_assoc PF16619.5 CDJ42666.1 - 0.023 14.7 0.2 0.023 14.7 0.2 7.7 7 2 0 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 CCB2_CCB4 PF11152.8 CDJ42666.1 - 0.07 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 GRP PF07172.11 CDJ42666.1 - 0.33 11.6 5.4 4.9 7.9 0.5 3.4 3 0 0 3 3 3 0 Glycine rich protein family MMR1 PF08505.10 CDJ42667.1 - 0.9 9.8 25.0 1.3 9.2 25.0 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Nop53 PF07767.11 CDJ42667.1 - 1.2 8.4 31.1 1.4 8.2 31.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIA PF03153.13 CDJ42668.1 - 0.66 9.9 10.9 0.69 9.9 10.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mitoc_mL59 PF18126.1 CDJ42669.1 - 0.00021 21.6 4.1 0.0076 16.5 4.1 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Sec6 PF06046.13 CDJ42669.1 - 0.038 12.4 0.0 0.049 12.0 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 Ank_2 PF12796.7 CDJ42670.1 - 1.9e-14 54.0 6.3 4.4e-13 49.6 0.6 4.2 4 2 1 5 5 5 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ42670.1 - 4.1e-12 45.1 8.7 0.00015 22.0 0.0 6.8 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 CDJ42670.1 - 3e-11 43.2 11.3 0.00028 21.2 0.4 6.7 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 CDJ42670.1 - 4.4e-11 43.1 0.3 3.6e-06 27.4 0.0 4.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ42670.1 - 2.7e-09 37.1 4.6 0.00012 22.3 0.6 4.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) SET PF00856.28 CDJ42670.1 - 0.016 15.6 0.1 0.053 13.9 0.0 2.0 2 1 0 2 2 2 0 SET domain TPR_17 PF13431.6 CDJ42670.1 - 0.15 12.5 0.2 0.7 10.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA PF00004.29 CDJ42672.1 - 2.2e-41 141.3 0.0 7.3e-41 139.7 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CDJ42672.1 - 2.3e-19 69.1 0.1 4.4e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CDJ42672.1 - 9.8e-12 44.5 0.1 2e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ42672.1 - 1.5e-06 28.3 0.1 7.1e-06 26.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ42672.1 - 3.9e-05 24.1 0.3 0.0046 17.4 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CDJ42672.1 - 8.6e-05 22.3 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDJ42672.1 - 0.00042 20.5 0.0 0.0017 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ42672.1 - 0.00071 19.9 0.6 0.081 13.2 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 CDJ42672.1 - 0.0029 17.8 0.1 0.0068 16.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDJ42672.1 - 0.0038 16.6 0.3 0.014 14.8 0.0 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CDJ42672.1 - 0.0098 15.3 0.1 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 KaiC PhoH PF02562.16 CDJ42672.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF815 PF05673.13 CDJ42672.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CDJ42672.1 - 0.025 14.3 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CDJ42672.1 - 0.04 13.7 0.1 0.11 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 CDJ42672.1 - 0.044 13.0 0.5 0.23 10.6 0.0 2.0 1 1 1 2 2 2 0 TIP49 P-loop domain ZapB PF06005.12 CDJ42672.1 - 0.064 13.7 1.3 0.24 11.9 0.4 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Sigma54_activat PF00158.26 CDJ42672.1 - 0.074 12.8 0.0 0.32 10.7 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 CDJ42672.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Exo_endo_phos PF03372.23 CDJ42675.1 - 1.9e-11 43.9 0.0 6.1e-11 42.3 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Gp58 PF07902.11 CDJ42676.1 - 0.2 9.9 0.1 0.22 9.8 0.1 1.0 1 0 0 1 1 1 0 gp58-like protein Seryl_tRNA_N PF02403.22 CDJ42677.1 - 0.24 11.7 15.8 0.033 14.4 8.6 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3535 PF12054.8 CDJ42677.1 - 5.7 6.1 13.6 15 4.7 13.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3535) Mod_r PF07200.13 CDJ42677.1 - 9.1 6.4 18.8 6 7.0 17.5 1.4 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Gln_amidase PF15644.6 CDJ42678.1 - 0.016 16.3 0.3 0.016 16.3 0.3 2.5 2 1 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase PACT_coil_coil PF10495.9 CDJ42678.1 - 0.027 15.1 3.8 0.027 15.1 3.8 2.4 2 1 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein MAT1 PF06391.13 CDJ42678.1 - 2.2 8.0 14.5 1.9 8.3 13.3 1.6 1 1 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 SNF2_N PF00176.23 CDJ42681.1 - 3.7e-37 127.9 0.0 2.6e-30 105.3 0.0 2.7 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ42681.1 - 1.6e-09 38.1 0.0 4.5e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 CDJ42681.1 - 4.5e-07 29.8 5.3 4.5e-07 29.8 5.3 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDJ42681.1 - 3.8e-05 23.9 11.8 3.8e-05 23.9 11.8 4.1 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ42681.1 - 0.00063 19.6 11.7 0.00076 19.3 6.8 3.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ42681.1 - 0.0011 19.1 6.6 0.0011 19.1 6.6 4.1 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDJ42681.1 - 0.0012 18.8 16.1 0.0012 18.8 16.1 3.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDJ42681.1 - 0.0016 18.3 14.8 0.023 14.5 14.9 3.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ42681.1 - 0.0039 17.0 6.8 0.0039 17.0 6.8 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CDJ42681.1 - 3.7 7.4 9.5 9 6.2 7.7 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain AP2 PF00847.20 CDJ42682.1 - 1e-09 38.5 3.7 2.5e-05 24.4 0.7 4.7 6 0 0 6 6 6 2 AP2 domain HS1_rep PF02218.15 CDJ42683.1 - 0.38 11.1 1.3 0.74 10.2 1.3 1.5 1 0 0 1 1 1 0 Repeat in HS1/Cortactin Pro_isomerase PF00160.21 CDJ42684.1 - 1.6e-31 109.7 0.0 6.5e-31 107.7 0.0 2.1 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_60s PF00428.19 CDJ42684.1 - 0.011 16.3 12.1 0.011 16.3 12.1 4.1 4 0 0 4 4 4 0 60s Acidic ribosomal protein ASFV_J13L PF05568.11 CDJ42684.1 - 0.13 12.1 2.4 0.35 10.6 2.4 1.8 1 0 0 1 1 1 0 African swine fever virus J13L protein Allexi_40kDa PF05549.11 CDJ42684.1 - 0.43 10.0 3.2 1.1 8.8 3.2 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein Lin-8 PF03353.15 CDJ42684.1 - 1.3 8.5 16.5 0.17 11.4 3.5 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist RSRP PF17069.5 CDJ42684.1 - 4.7 6.7 49.2 0.19 11.3 28.0 2.4 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 LCD1 PF09798.9 CDJ42684.1 - 4.8 5.6 7.8 6.5 5.1 7.8 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein KH_1 PF00013.29 CDJ42686.1 - 1.5e-17 63.2 0.0 5.9e-08 32.4 0.1 2.5 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 CDJ42686.1 - 3.8e-06 26.7 1.1 0.073 13.0 0.0 2.7 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CDJ42686.1 - 6.2e-05 22.7 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 KH domain SUIM_assoc PF16619.5 CDJ42686.1 - 0.048 13.7 23.9 0.24 11.5 0.2 4.0 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 KH_5 PF13184.6 CDJ42686.1 - 0.57 10.3 1.6 17 5.5 0.1 2.5 2 0 0 2 2 2 0 NusA-like KH domain RskA PF10099.9 CDJ42686.1 - 4.3 7.6 51.1 0.14 12.5 2.6 3.8 3 1 1 4 4 4 0 Anti-sigma-K factor rskA NAD_kinase PF01513.21 CDJ42687.1 - 0.0003 20.1 0.6 0.53 9.4 0.0 3.2 3 0 0 3 3 3 2 ATP-NAD kinase DDHD PF02862.17 CDJ42687.1 - 0.011 16.0 7.2 0.046 13.9 1.5 2.4 2 0 0 2 2 2 0 DDHD domain Exonuc_VII_L PF02601.15 CDJ42687.1 - 0.12 12.0 13.2 0.4 10.2 7.2 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit DAGK_cat PF00781.24 CDJ42687.1 - 0.35 10.5 0.0 0.35 10.5 0.0 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain PNISR PF15996.5 CDJ42687.1 - 0.5 10.6 25.4 0.21 11.9 9.7 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Neur_chan_memb PF02932.16 CDJ42687.1 - 1.4 8.9 15.7 0.65 10.0 3.7 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BORG_CEP PF14957.6 CDJ42687.1 - 2 9.6 14.6 6.7 7.9 5.2 2.6 2 0 0 2 2 2 0 Cdc42 effector EPL1 PF10513.9 CDJ42687.1 - 2.2 8.6 22.3 4.7 7.6 3.6 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Med15 PF09606.10 CDJ42687.1 - 2.9 6.5 51.6 0.8 8.3 26.3 2.5 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DnaJ PF00226.31 CDJ42690.1 - 1.3e-20 73.2 0.2 1.3e-20 73.2 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 CDJ42690.1 - 3.1e-11 43.2 0.0 8.3e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 CDJ42690.1 - 0.07 13.5 0.0 0.46 10.8 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like Transket_pyr PF02779.24 CDJ42691.1 - 3.5e-43 147.4 0.2 6.4e-43 146.5 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDJ42691.1 - 3.6e-07 30.1 0.3 0.013 15.4 0.0 2.4 1 1 1 2 2 2 2 Transketolase, C-terminal domain BOP1NT PF08145.12 CDJ42692.1 - 5e-25 88.9 0.1 5e-25 88.9 0.1 2.4 3 0 0 3 3 3 1 BOP1NT (NUC169) domain RRM_1 PF00076.22 CDJ42692.1 - 1.8e-14 53.3 0.1 3.9e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 CDJ42692.1 - 0.00038 21.2 0.0 33 5.6 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Spt20 PF12090.8 CDJ42692.1 - 0.01 15.5 10.9 0.21 11.2 1.2 2.7 2 0 0 2 2 2 0 Spt20 family RRM_7 PF16367.5 CDJ42692.1 - 0.011 15.8 0.0 0.041 14.0 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif AIP3 PF03915.13 CDJ42693.1 - 0.032 13.3 1.7 0.063 12.4 1.7 1.4 1 0 0 1 1 1 0 Actin interacting protein 3 DUF2052 PF09747.9 CDJ42693.1 - 0.81 9.8 19.9 0.18 11.9 3.6 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF2057 PF09829.9 CDJ42693.1 - 2.1 8.5 0.0 2.1 8.5 0.0 5.8 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2057) SART-1 PF03343.13 CDJ42693.1 - 4.7 5.7 25.1 0.11 11.0 6.3 2.2 2 0 0 2 2 2 0 SART-1 family Atg14 PF10186.9 CDJ42693.1 - 9.6 5.2 7.3 21 4.1 7.3 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CCSAP PF15748.5 CDJ42693.1 - 9.9 6.2 20.5 1.1 9.4 8.7 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Sugar_tr PF00083.24 CDJ42694.1 - 4.6e-47 160.9 22.4 3.2e-32 112.0 1.5 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDJ42694.1 - 3e-16 59.3 59.9 1.3e-10 40.7 38.7 4.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Spt20 PF12090.8 CDJ42694.1 - 0.00023 20.9 11.4 0.00023 20.9 11.4 4.0 4 0 0 4 4 4 2 Spt20 family DUF4834 PF16118.5 CDJ42694.1 - 0.021 15.8 0.1 0.021 15.8 0.1 3.4 4 0 0 4 4 3 0 Domain of unknown function (DUF4834) IBV_3C PF03620.13 CDJ42694.1 - 0.11 13.0 3.6 11 6.6 0.4 2.8 2 0 0 2 2 2 0 IBV 3C protein PRIMA1 PF16101.5 CDJ42694.1 - 0.34 11.0 3.3 0.6 10.2 0.5 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 FHIPEP PF00771.20 CDJ42694.1 - 0.55 8.6 4.6 0.18 10.3 0.6 2.0 2 0 0 2 2 2 0 FHIPEP family Band_3_cyto PF07565.13 CDJ42694.1 - 0.8 9.5 8.6 0.22 11.3 1.5 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain CLN3 PF02487.17 CDJ42694.1 - 0.85 8.6 9.4 0.42 9.6 0.3 3.3 4 0 0 4 4 4 0 CLN3 protein V_ATPase_I PF01496.19 CDJ42694.1 - 1.2 6.9 7.8 0.093 10.6 2.2 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF1681 PF07933.14 CDJ42694.1 - 3.6 7.3 5.4 0.45 10.2 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1681) GNAT_acetyltr_2 PF13718.6 CDJ42694.1 - 8.3 5.7 8.5 1.2 8.5 3.0 2.1 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Lipase_GDSL PF00657.22 CDJ42695.1 - 1.5 8.8 8.2 2.2 8.2 8.2 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Dehalogenase PF13486.6 CDJ42695.1 - 6.6 6.0 12.0 6.9 6.0 12.0 1.0 1 0 0 1 1 1 0 Reductive dehalogenase subunit Dus PF01207.17 CDJ42696.1 - 9.1e-11 41.4 8.9 1.2e-08 34.4 8.9 2.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF3138 PF11336.8 CDJ42696.1 - 0.56 8.8 6.0 0.8 8.3 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF5588 PF17826.1 CDJ42697.1 - 0.00061 18.8 9.4 0.00079 18.4 9.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5588) CAP59_mtransfer PF11735.8 CDJ42697.1 - 0.00076 19.2 1.2 0.001 18.8 1.2 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF4207 PF13904.6 CDJ42697.1 - 0.0059 16.3 6.6 0.0059 16.3 6.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4207) FAM199X PF15814.5 CDJ42697.1 - 0.016 14.3 7.9 0.021 13.9 7.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X TFIIA PF03153.13 CDJ42697.1 - 0.19 11.7 18.0 0.22 11.5 18.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GET2 PF08690.10 CDJ42697.1 - 0.2 11.3 10.7 0.25 11.0 10.7 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 DUF3446 PF11928.8 CDJ42697.1 - 0.23 11.8 15.2 19 5.7 15.3 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain Corona_nucleoca PF00937.18 CDJ42697.1 - 0.26 10.3 10.3 0.41 9.6 10.3 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein ATP-synt_E PF05680.12 CDJ42697.1 - 0.31 11.4 6.7 0.46 10.9 1.5 2.2 2 0 0 2 2 2 0 ATP synthase E chain RAP1 PF07218.11 CDJ42697.1 - 0.38 9.0 3.4 0.37 9.0 3.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SOBP PF15279.6 CDJ42697.1 - 1 9.9 10.4 1.4 9.5 10.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RSF PF14876.6 CDJ42697.1 - 4.2 6.2 14.0 0.83 8.5 2.0 2.1 1 1 1 2 2 2 0 Respiratory growth transcriptional regulator Nop14 PF04147.12 CDJ42698.1 - 2.1e-12 46.2 64.0 2.1e-12 46.2 64.0 5.9 4 1 1 5 5 5 3 Nop14-like family bMG5 PF17972.1 CDJ42699.1 - 0.023 15.1 0.1 0.032 14.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain Apt1 PF10351.9 CDJ42699.1 - 0.057 12.3 13.0 0.073 11.9 13.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ42699.1 - 0.77 9.6 16.3 0.98 9.3 16.3 1.1 1 0 0 1 1 1 0 SPX domain CopD PF05425.13 CDJ42700.1 - 0.043 14.2 0.1 0.043 14.2 0.1 2.9 2 1 1 3 3 3 0 Copper resistance protein D HSCB_C PF07743.13 CDJ42701.1 - 4.6e-10 39.8 4.4 4.6e-10 39.8 4.4 2.5 3 0 0 3 3 3 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CDJ42701.1 - 0.00035 20.6 0.2 0.00077 19.5 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.7 CDJ42701.1 - 0.25 11.4 0.2 0.25 11.4 0.2 2.7 2 1 0 2 2 2 0 Double zinc ribbon SUIM_assoc PF16619.5 CDJ42702.1 - 0.0024 17.9 4.5 0.0024 17.9 4.5 8.5 6 4 2 8 8 8 1 Unstructured region C-term to UIM in Ataxin3 BCS1_N PF08740.11 CDJ42702.1 - 0.035 14.1 0.1 0.035 14.1 0.1 2.4 3 0 0 3 3 3 0 BCS1 N terminal FAST_1 PF06743.15 CDJ42702.1 - 0.056 13.4 1.0 0.13 12.2 1.0 1.5 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 Nha1_C PF08619.10 CDJ42703.1 - 0.52 9.5 0.0 0.52 9.5 0.0 8.1 7 2 0 7 7 7 0 Alkali metal cation/H+ antiporter Nha1 C terminus EF-hand_1 PF00036.32 CDJ42704.1 - 0.0029 17.1 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ42704.1 - 0.0055 16.5 0.0 5.4 7.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CDJ42704.1 - 0.035 14.5 0.0 11 6.6 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair Presenilin PF01080.17 CDJ42704.1 - 0.071 11.9 2.5 0.14 10.9 2.5 1.4 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ42704.1 - 0.17 12.9 4.4 1.5 9.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) SR-25 PF10500.9 CDJ42704.1 - 6.9 6.2 14.4 2.2 7.8 0.4 2.8 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Glyco_hydro_19 PF00182.19 CDJ42705.1 - 5.8e-08 32.9 0.2 3.7e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Chitinase class I PUL PF08324.11 CDJ42706.1 - 1.1e-30 106.9 5.9 1.1e-30 106.9 5.9 2.0 2 0 0 2 2 2 1 PUL domain PFU PF09070.11 CDJ42706.1 - 1.6e-23 83.1 0.0 3.6e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CDJ42706.1 - 6.8e-17 61.5 16.7 0.001 19.8 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat SR-25 PF10500.9 CDJ42706.1 - 0.12 11.9 25.2 0.28 10.8 5.8 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein EBP50_C PF09007.11 CDJ42706.1 - 4.9 8.1 13.1 0.62 11.1 0.3 3.3 3 0 0 3 3 3 0 EBP50, C-terminal Ccdc124 PF06244.12 CDJ42712.1 - 6.8e-33 114.0 27.7 3.3e-30 105.3 27.7 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 CDJ42712.1 - 0.00011 22.6 0.3 0.00011 22.6 0.3 2.6 2 1 0 2 2 2 1 HMG (high mobility group) box CHDNT PF08073.12 CDJ42712.1 - 0.016 15.2 0.3 0.027 14.4 0.3 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.13 CDJ42712.1 - 3.2 8.3 12.5 2.5e+02 2.1 12.5 2.3 1 1 0 1 1 1 0 YABBY protein TMPIT PF07851.13 CDJ42712.1 - 8.4 5.5 8.1 11 5.2 8.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein MIP-T3_C PF17749.1 CDJ42713.1 - 0.021 14.8 8.4 0.055 13.4 4.0 2.7 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region zf-C4H2 PF10146.9 CDJ42713.1 - 0.045 14.1 6.5 0.13 12.5 6.5 1.9 1 0 0 1 1 1 0 Zinc finger-containing protein CENP-F_leu_zip PF10473.9 CDJ42713.1 - 0.25 11.4 29.2 0.12 12.4 5.3 3.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fzo_mitofusin PF04799.13 CDJ42713.1 - 0.35 10.4 5.5 0.75 9.3 5.5 1.6 1 0 0 1 1 1 0 fzo-like conserved region Spc7 PF08317.11 CDJ42713.1 - 0.57 9.0 25.4 0.024 13.5 15.1 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 CDJ42713.1 - 1.6 6.5 6.7 2.7 5.8 6.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1216 PF06746.11 CDJ42713.1 - 1.7 8.6 6.1 3.7 7.6 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) DUF641 PF04859.12 CDJ42713.1 - 1.8 8.9 11.3 0.66 10.3 6.6 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Baculo_PEP_C PF04513.12 CDJ42713.1 - 1.8 8.6 7.3 0.2 11.7 0.7 2.4 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MAD PF05557.13 CDJ42713.1 - 2.3 6.4 23.6 5.8 5.1 23.7 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein FlaC_arch PF05377.11 CDJ42713.1 - 2.8 8.4 5.2 7.9 7.0 2.3 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 CDJ42713.1 - 7.7 6.3 13.8 2.5 7.9 10.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 CDJ42713.1 - 8.6 5.7 21.6 0.83 9.1 15.2 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 WD40 PF00400.32 CDJ42714.1 - 9.6e-14 51.6 0.5 6.8e-06 26.7 0.0 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat tRNA-synt_1c PF00749.21 CDJ42715.1 - 3.3e-63 213.5 0.0 3.6e-32 111.5 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (E and Q), catalytic domain WD40 PF00400.32 CDJ42715.1 - 2.1e-31 107.5 27.4 3e-07 31.0 0.6 11.3 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ42715.1 - 2.9e-12 46.7 0.0 0.11 12.9 0.0 7.0 4 3 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CDJ42715.1 - 0.07 11.7 0.0 0.17 10.4 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 CDJ42715.1 - 0.083 11.8 0.1 23 3.8 0.0 3.6 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Hydrolase_4 PF12146.8 CDJ42716.1 - 1.4e-12 47.4 0.5 3.3e-08 33.1 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CDJ42716.1 - 2.9e-09 36.7 0.3 2.3e-06 27.3 0.0 3.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CDJ42716.1 - 6.8e-07 30.1 0.0 1.4e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ42716.1 - 0.00024 20.8 0.1 0.0092 15.6 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 CDJ42716.1 - 0.00079 19.1 0.1 0.04 13.6 0.0 2.3 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Fe_dep_repr_C PF02742.15 CDJ42716.1 - 0.0051 16.9 0.0 8.8 6.5 0.0 3.5 4 0 0 4 4 4 2 Iron dependent repressor, metal binding and dimerisation domain DUF818 PF05677.12 CDJ42716.1 - 0.0057 15.6 0.1 0.0084 15.1 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 CDJ42716.1 - 0.033 14.0 0.3 0.3 10.9 0.0 2.4 3 1 0 3 3 3 0 Phospholipase/Carboxylesterase Pkinase PF00069.25 CDJ42717.1 - 2.4e-23 82.9 4.3 3.5e-11 43.0 0.0 4.0 5 0 0 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ42717.1 - 2.9e-09 36.6 0.0 0.00028 20.3 0.0 4.4 4 0 0 4 4 4 3 Protein tyrosine kinase DHHC PF01529.20 CDJ42718.1 - 2.9e-38 131.0 11.9 7.7e-37 126.4 6.5 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase Yip1 PF04893.17 CDJ42718.1 - 0.23 11.2 10.1 0.49 10.1 0.4 2.3 2 0 0 2 2 2 0 Yip1 domain RDD PF06271.12 CDJ42718.1 - 1.1 9.5 8.6 5.6 7.2 1.0 2.2 2 0 0 2 2 2 0 RDD family Sigma_reg_N PF13800.6 CDJ42718.1 - 1.8 8.9 3.8 3.7 7.9 0.0 2.7 3 0 0 3 3 3 0 Sigma factor regulator N-terminal TMEM213 PF15192.6 CDJ42718.1 - 2.7 8.0 10.0 0.12 12.4 3.7 2.0 2 0 0 2 2 2 0 TMEM213 family DUF2207 PF09972.9 CDJ42718.1 - 4.1 6.0 4.1 4.1 6.1 0.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Colicin_V PF02674.16 CDJ42718.1 - 4.8 7.1 18.3 0.24 11.4 6.0 2.5 2 1 0 2 2 2 0 Colicin V production protein Bac_export_2 PF01312.19 CDJ42718.1 - 6.8 5.8 6.5 14 4.7 0.7 2.0 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family START PF01852.19 CDJ42719.1 - 1.6e-11 44.1 0.0 9.7e-06 25.1 0.0 2.3 2 0 0 2 2 2 2 START domain TP_methylase PF00590.20 CDJ42721.1 - 2.3e-21 76.7 0.0 6.3e-21 75.3 0.0 1.7 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases UQ_con PF00179.26 CDJ42722.1 - 1.7e-47 160.6 0.0 2e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ42722.1 - 0.00028 20.6 0.0 0.00032 20.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ42722.1 - 0.013 15.7 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain Rhomboid PF01694.22 CDJ42724.1 - 5e-18 65.5 14.0 4.3e-14 52.8 4.1 2.6 2 1 1 3 3 3 2 Rhomboid family DUF2705 PF10920.8 CDJ42724.1 - 0.011 15.1 0.9 0.015 14.6 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2705) APG5 PF04106.12 CDJ42725.1 - 1.2e-21 77.4 0.0 1.7e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 U79_P34 PF03064.16 CDJ42725.1 - 0.067 12.5 0.6 0.11 11.8 0.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDK2AP PF09806.9 CDJ42726.1 - 2.3 8.2 7.1 4.4 7.3 7.1 1.3 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein MBOAT PF03062.19 CDJ42727.1 - 3.5e-27 95.7 32.7 7e-27 94.7 32.7 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CDJ42727.1 - 0.0014 18.9 3.8 0.0045 17.2 3.8 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SRP-alpha_N PF04086.13 CDJ42727.1 - 0.13 12.2 3.9 0.27 11.1 3.6 1.6 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SUIM_assoc PF16619.5 CDJ42727.1 - 2.7 8.1 13.4 1.6 8.9 1.5 2.7 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 NACHT_N PF17100.5 CDJ42728.1 - 0.18 11.6 0.5 0.33 10.8 0.5 1.3 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase MRP-S23 PF10484.9 CDJ42730.1 - 2.8 8.2 6.5 0.86 9.9 0.9 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 TFIIA PF03153.13 CDJ42731.1 - 0.22 11.5 39.5 0.24 11.3 2.7 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit OST3_OST6 PF04756.13 CDJ42735.1 - 0.22 10.8 0.0 0.83 8.9 0.0 1.8 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family zf-C2H2_9 PF16293.5 CDJ42735.1 - 0.22 11.4 0.0 0.48 10.3 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) CReP_N PF10472.9 CDJ42738.1 - 0.013 14.4 0.6 0.017 14.0 0.6 1.1 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor VIT1 PF01988.19 CDJ42739.1 - 0.0047 16.8 2.4 0.0047 16.8 2.4 2.8 3 0 0 3 3 3 1 VIT family FAD_binding_3 PF01494.19 CDJ42741.1 - 5e-22 78.6 3.6 2.1e-13 50.2 0.4 4.6 5 0 0 5 5 5 3 FAD binding domain Ribosomal_L14 PF00238.19 CDJ42743.1 - 1.2e-17 64.1 0.0 1.8e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RskA PF10099.9 CDJ42743.1 - 5.8 7.2 14.0 24 5.2 14.0 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA AP2 PF00847.20 CDJ42744.1 - 1.1e-08 35.2 0.2 1.1e-08 35.2 0.2 2.3 2 0 0 2 2 2 1 AP2 domain Duffy_binding PF05424.11 CDJ42744.1 - 0.37 10.8 7.1 0.14 12.1 2.4 2.6 2 0 0 2 2 2 0 Duffy binding domain Apt1 PF10351.9 CDJ42745.1 - 0.31 9.9 10.4 0.063 12.1 2.3 2.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain WD40 PF00400.32 CDJ42746.1 - 5.8e-13 49.1 0.1 0.00011 23.0 0.1 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ42746.1 - 1.4e-05 25.3 0.1 0.011 16.0 0.0 3.3 3 1 1 4 4 3 2 Anaphase-promoting complex subunit 4 WD40 domain AP3D1 PF06375.11 CDJ42746.1 - 0.0072 16.6 8.8 0.47 10.7 0.1 2.2 2 0 0 2 2 2 2 AP-3 complex subunit delta-1 Nup160 PF11715.8 CDJ42746.1 - 0.014 14.1 0.0 0.014 14.1 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 BNIP3 PF06553.12 CDJ42746.1 - 0.027 14.1 3.1 0.047 13.4 3.1 1.4 1 0 0 1 1 1 0 BNIP3 PRC2_HTH_1 PF18118.1 CDJ42746.1 - 0.033 15.0 6.8 0.62 10.9 2.5 2.3 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain DUF702 PF05142.12 CDJ42746.1 - 0.037 14.5 5.5 2.1 8.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) TFIIA PF03153.13 CDJ42746.1 - 0.1 12.6 15.5 0.46 10.4 2.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 CDJ42746.1 - 0.13 12.1 8.1 0.035 14.0 2.5 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Eapp_C PF10238.9 CDJ42746.1 - 0.28 11.3 9.1 0.77 9.8 1.4 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Coilin_N PF15862.5 CDJ42746.1 - 0.28 11.0 8.2 16 5.3 0.0 2.4 2 0 0 2 2 2 0 Coilin N-terminus Chorein_N PF12624.7 CDJ42746.1 - 0.33 11.1 6.5 0.34 11.0 2.7 2.2 2 0 0 2 2 2 0 N-terminal region of Chorein or VPS13 DUF2722 PF10846.8 CDJ42746.1 - 0.48 9.3 16.4 0.25 10.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Afi1 PF07792.12 CDJ42746.1 - 0.58 10.6 7.8 0.68 10.4 3.0 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF913 PF06025.12 CDJ42746.1 - 0.6 9.0 3.1 2.6 6.9 1.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Eaf7 PF07904.13 CDJ42746.1 - 0.8 10.1 3.5 3.1 8.2 0.0 2.5 2 1 0 2 2 2 0 Chromatin modification-related protein EAF7 S36_mt PF10937.8 CDJ42746.1 - 1.1 10.8 5.8 2 10.1 0.5 2.3 2 0 0 2 2 2 0 Ribosomal protein S36, mitochondrial TERB2 PF15101.6 CDJ42746.1 - 1.2 9.2 14.5 0.49 10.4 0.3 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Spt20 PF12090.8 CDJ42746.1 - 1.5 8.4 25.6 1.3 8.6 9.5 2.1 2 0 0 2 2 2 0 Spt20 family DUF5308 PF17233.2 CDJ42746.1 - 1.8 8.7 9.3 4.5 7.5 5.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5308) CENP-B_dimeris PF09026.10 CDJ42746.1 - 2 8.9 6.8 1.9 8.9 5.4 1.6 1 1 0 1 1 1 0 Centromere protein B dimerisation domain BRF1 PF07741.13 CDJ42746.1 - 2.2 8.7 11.3 2.7 8.4 0.4 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain eIF-3_zeta PF05091.12 CDJ42746.1 - 4.8 6.1 9.7 1 8.3 0.8 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PPL5 PF18168.1 CDJ42746.1 - 7.4 5.8 8.7 1.1 8.5 2.0 2.0 2 0 0 2 2 2 0 Prim-pol family 5 DUF4770 PF15994.5 CDJ42746.1 - 8.5 6.6 8.0 5.5 7.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) EF-hand_6 PF13405.6 CDJ42747.1 - 0.00068 19.4 0.5 0.0015 18.3 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CDJ42747.1 - 0.024 14.1 0.2 0.054 13.0 0.2 1.6 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 CDJ42747.1 - 0.038 13.5 0.2 0.077 12.6 0.2 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 CDJ42747.1 - 0.043 14.3 0.2 0.11 13.0 0.2 1.8 1 1 0 1 1 1 0 EF-hand domain pair RPAP1_C PF08620.10 CDJ42748.1 - 1.5e-19 69.9 0.0 5.7e-19 68.0 0.0 2.2 1 1 0 1 1 1 1 RPAP1-like, C-terminal CNOT1_HEAT PF16418.5 CDJ42748.1 - 7 6.7 11.6 9.7 6.3 6.6 3.5 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Vps39_2 PF10367.9 CDJ42749.1 - 0.44 11.0 7.6 0.45 11.0 7.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 HI0933_like PF03486.14 CDJ42749.1 - 2.5 6.7 10.2 2.5 6.7 10.2 1.0 1 0 0 1 1 1 0 HI0933-like protein G-gamma PF00631.22 CDJ42749.1 - 2.8 8.0 15.4 84 3.3 9.6 2.3 1 1 1 2 2 2 0 GGL domain Minor_tail_Z PF06763.11 CDJ42749.1 - 9 6.0 14.1 14 5.4 14.1 1.4 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) DUF3313 PF11769.8 CDJ42749.1 - 9.5 6.0 10.0 19 5.0 10.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3313) ORC5_C PF14630.6 CDJ42750.1 - 0.013 15.1 0.0 0.013 15.0 0.0 1.0 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus TMEM51 PF15345.6 CDJ42750.1 - 5.2 6.8 7.7 6.1 6.6 7.7 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 RAP PF08373.10 CDJ42751.1 - 1.2e-05 25.2 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RAP domain BHD_3 PF10405.9 CDJ42752.1 - 1.6e-05 25.2 0.0 3.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 CDJ42752.1 - 1.8e-05 24.4 0.0 0.0038 16.9 0.0 3.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 CDJ42752.1 - 0.00029 21.7 10.3 0.00029 21.7 10.3 4.3 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 DMAP1 PF05499.12 CDJ42752.1 - 0.0024 17.8 8.1 0.09 12.7 0.7 3.6 2 0 0 2 2 2 2 DNA methyltransferase 1-associated protein 1 (DMAP1) Transglut_core PF01841.19 CDJ42752.1 - 0.01 16.3 0.1 0.12 12.9 0.1 2.9 1 0 0 1 1 1 0 Transglutaminase-like superfamily Pkinase PF00069.25 CDJ42753.1 - 3e-35 121.9 0.6 1e-34 120.1 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ42753.1 - 7.3e-15 54.9 0.1 6.1e-14 51.9 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 CDJ42753.1 - 0.0016 18.1 0.4 0.0082 15.8 0.0 2.4 2 0 0 2 2 2 1 RIO1 family ATP-synt_D PF01813.17 CDJ42754.1 - 3.2e-60 203.3 2.7 4.1e-60 203.0 2.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit D CorA PF01544.18 CDJ42754.1 - 0.077 12.3 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Spore_SspJ PF09575.10 CDJ42754.1 - 0.71 10.3 4.8 1 9.8 1.4 2.5 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) SUIM_assoc PF16619.5 CDJ42755.1 - 0.86 9.7 12.9 0.23 11.5 1.0 2.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DEAD PF00270.29 CDJ42756.1 - 3.8e-43 147.3 0.0 1.2e-42 145.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ42756.1 - 1.6e-23 83.1 0.0 1.6e-23 83.1 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Pkinase PF00069.25 CDJ42757.1 - 8.6e-40 136.8 0.0 3.9e-23 82.2 0.0 3.8 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ42757.1 - 2.9e-27 95.6 0.0 1.7e-17 63.6 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 CDJ42757.1 - 0.00096 18.5 0.0 0.0035 16.7 0.0 2.0 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ42757.1 - 0.004 16.5 0.7 0.004 16.5 0.7 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ42757.1 - 0.039 13.9 0.1 0.039 13.9 0.1 3.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family LSM PF01423.22 CDJ42759.1 - 3.1e-20 71.6 0.1 3.6e-20 71.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDJ42759.1 - 0.09 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF2235 PF09994.9 CDJ42760.1 - 0.13 11.6 0.0 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DEAD PF00270.29 CDJ42761.1 - 2.7e-36 125.0 0.0 5.3e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ42761.1 - 1.1e-24 86.9 0.0 3.5e-24 85.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ42761.1 - 7.2e-08 32.6 0.0 2.4e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 CDJ42761.1 - 6.7e-06 25.1 0.0 1.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 CDJ42761.1 - 0.0021 17.8 0.0 0.94 9.1 0.0 2.4 2 0 0 2 2 2 2 SWI2/SNF2 ATPase AAA_22 PF13401.6 CDJ42761.1 - 0.029 14.7 0.1 3.5 7.9 0.1 3.9 2 2 0 2 2 2 0 AAA domain AP2 PF00847.20 CDJ42762.1 - 5.6e-08 32.9 0.1 1.5e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 AP2 domain HECT PF00632.25 CDJ42765.1 - 4e-93 312.3 0.0 7.2e-93 311.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_60s PF00428.19 CDJ42765.1 - 0.0025 18.4 8.1 0.0025 18.4 8.1 8.7 8 1 1 9 9 9 1 60s Acidic ribosomal protein LIM PF00412.22 CDJ42766.1 - 0.051 13.8 9.1 0.1 12.8 9.1 1.6 1 0 0 1 1 1 0 LIM domain zf-RING_2 PF13639.6 CDJ42766.1 - 1.3 9.5 8.2 3.2 8.2 8.2 1.7 1 1 0 1 1 1 0 Ring finger domain DnaJ PF00226.31 CDJ42767.1 - 9.4e-24 83.3 0.1 9.4e-24 83.3 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain zf-C2H2 PF00096.26 CDJ42767.1 - 8e-08 32.3 2.6 0.0072 16.7 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 CDJ42767.1 - 1.4e-07 31.6 7.2 2.4e-05 24.6 0.5 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ42767.1 - 2.2e-07 31.0 8.7 1.3e-05 25.3 0.8 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDJ42767.1 - 4.2e-07 30.2 7.1 0.0062 16.8 0.3 3.8 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CDJ42767.1 - 1.7e-06 28.4 3.4 0.02 15.7 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ42767.1 - 2.4e-05 24.2 2.4 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-MYST PF17772.1 CDJ42767.1 - 0.0064 16.1 1.1 0.011 15.4 0.1 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain zf-DBF PF07535.12 CDJ42767.1 - 0.25 11.5 1.6 0.55 10.4 0.5 2.2 2 0 0 2 2 2 0 DBF zinc finger Kinesin PF00225.23 CDJ42768.1 - 8.8e-69 232.0 0.0 5.6e-68 229.3 0.0 2.0 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ42768.1 - 6.5e-13 48.9 0.0 3.6e-12 46.4 0.0 2.1 2 1 0 2 2 2 1 Microtubule binding Solute_trans_a PF03619.16 CDJ42769.1 - 4.6e-33 114.9 9.5 2e-14 53.8 0.8 3.1 3 0 0 3 3 3 3 Organic solute transporter Ostalpha TPR_1 PF00515.28 CDJ42772.1 - 7.8e-11 41.3 2.2 0.024 14.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ42772.1 - 1.5e-09 37.2 5.9 0.021 14.9 0.3 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ42772.1 - 9.6e-08 32.1 0.9 3.9e-06 26.9 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ42772.1 - 3.2e-07 30.7 6.6 0.0012 19.3 4.9 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ42772.1 - 4.4e-07 29.5 12.8 0.00029 20.5 0.5 3.6 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.6 CDJ42772.1 - 3.4e-06 27.6 8.2 0.0028 18.3 0.8 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ42772.1 - 5.2e-05 23.2 3.2 0.037 14.1 0.2 3.3 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 CDJ42772.1 - 7.5e-05 23.2 10.2 0.12 13.3 0.3 4.2 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ42772.1 - 0.00014 22.3 6.1 3.6 8.4 0.0 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ42772.1 - 0.00059 19.9 2.6 0.23 11.8 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ42772.1 - 0.00073 19.7 1.9 0.0083 16.3 1.1 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CDJ42772.1 - 0.0008 19.3 0.7 0.58 10.3 0.1 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 CDJ42772.1 - 0.00088 19.6 6.9 0.004 17.4 2.9 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ42772.1 - 0.0057 16.9 8.1 0.23 11.7 0.2 3.6 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ42772.1 - 0.0094 16.3 1.9 0.098 13.1 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Paf67 PF10255.9 CDJ42772.1 - 0.017 14.2 0.4 0.022 13.8 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 DUF3752 PF12572.8 CDJ42772.1 - 0.34 11.4 9.6 0.72 10.4 9.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DUF4391 PF14335.6 CDJ42772.1 - 2.1 8.0 7.8 4.9 6.8 7.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4391) Aha1_N PF09229.11 CDJ42773.1 - 3.1e-18 66.3 1.4 5.7e-18 65.4 0.0 2.0 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal TPH PF13868.6 CDJ42773.1 - 0.0078 14.8 9.9 0.016 13.7 9.9 1.5 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain TFIIF_alpha PF05793.12 CDJ42773.1 - 0.019 13.6 16.0 0.022 13.4 16.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ARA70 PF12489.8 CDJ42773.1 - 0.02 15.1 4.8 0.02 15.1 4.8 1.8 2 0 0 2 2 2 0 Nuclear coactivator ERM PF00769.19 CDJ42773.1 - 0.052 13.3 12.3 0.1 12.4 12.3 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ABC_tran_Xtn PF12848.7 CDJ42773.1 - 0.082 13.0 6.6 0.22 11.6 6.6 1.7 1 0 0 1 1 1 0 ABC transporter DUF755 PF05501.11 CDJ42773.1 - 0.27 11.5 10.1 0.58 10.4 10.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MPM1 PF17234.2 CDJ42773.1 - 0.62 10.3 10.0 1.2 9.4 10.0 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF4551 PF15087.6 CDJ42773.1 - 4.3 6.1 6.7 5 5.8 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SUIM_assoc PF16619.5 CDJ42773.1 - 5.9 7.0 12.3 10 6.3 5.9 2.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 EF-hand_6 PF13405.6 CDJ42774.1 - 0.0012 18.6 0.0 0.004 17.0 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CDJ42774.1 - 0.0088 15.5 0.0 0.023 14.2 0.0 1.8 1 0 0 1 1 1 1 EF hand ubiquitin PF00240.23 CDJ42774.1 - 0.024 14.4 0.0 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin family DAG_kinase_N PF14513.6 CDJ42774.1 - 1.4 9.1 3.9 0.56 10.4 0.4 2.0 1 1 1 2 2 2 0 Diacylglycerol kinase N-terminus ACOX PF01756.19 CDJ42775.1 - 8.6e-39 133.0 1.3 1.6e-38 132.1 1.3 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 CDJ42775.1 - 2.7e-16 60.2 0.2 5.7e-16 59.2 0.2 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 CDJ42775.1 - 6.7e-14 51.9 0.0 1.3e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CDJ42775.1 - 0.043 14.0 3.3 0.2 11.9 0.4 3.1 3 1 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain PP2C PF00481.21 CDJ42776.1 - 6.1e-39 134.2 0.0 8.1e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ42776.1 - 3.8e-07 29.9 0.0 1.3e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ42776.1 - 2.7e-05 24.2 0.0 0.0021 18.0 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Ephrin_rec_like PF07699.13 CDJ42778.1 - 9.4e-36 121.3 104.3 5.9e-08 32.3 10.9 12.3 10 2 2 12 12 12 9 Putative ephrin-receptor like TACI-CRD2 PF09305.10 CDJ42778.1 - 0.0022 17.9 1.8 0.0022 17.9 1.8 3.3 3 0 0 3 3 3 1 TACI, cysteine-rich domain Collagen PF01391.18 CDJ42780.1 - 2.2e-05 24.1 24.5 2.2e-05 24.1 24.5 3.7 2 1 1 3 3 3 1 Collagen triple helix repeat (20 copies) DUF3040 PF11239.8 CDJ42780.1 - 0.034 14.4 1.2 0.5 10.7 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Sec16 PF12932.7 CDJ42780.1 - 0.85 10.2 3.2 0.94 10.1 0.6 2.2 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region BatA PF07584.11 CDJ42780.1 - 1.4 9.3 4.2 7.5 7.0 4.2 2.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF3381 PF11861.8 CDJ42780.1 - 2.5 7.9 16.7 0.056 13.2 9.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) T2SSF PF00482.23 CDJ42780.1 - 5.3 7.0 12.7 0.58 10.1 0.1 3.4 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein F Brix PF04427.18 CDJ42781.1 - 1.3e-13 51.5 0.0 1.9e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain Alba PF01918.21 CDJ42782.1 - 3.6e-14 52.3 0.0 6.1e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Alba ATP-synt_ab PF00006.25 CDJ42784.1 - 3.8e-34 118.2 0.0 5.4e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain SR-25 PF10500.9 CDJ42785.1 - 4.1 7.0 46.5 6 6.4 23.2 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein RBDV_coat PF06593.11 CDJ42785.1 - 7.3 6.0 10.2 8.2 5.8 10.2 1.1 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein UBX PF00789.20 CDJ42786.1 - 9.9e-07 28.9 0.0 1.9e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain DDHD PF02862.17 CDJ42786.1 - 0.026 14.7 4.2 0.025 14.7 4.2 1.1 1 0 0 1 1 1 0 DDHD domain Pex14_N PF04695.13 CDJ42786.1 - 0.027 15.1 8.0 0.037 14.7 8.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Band_3_cyto PF07565.13 CDJ42786.1 - 1.3 8.8 12.7 1.8 8.3 12.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.17 CDJ42786.1 - 1.4 7.6 14.8 1.5 7.5 14.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 CDJ42786.1 - 1.7 8.0 9.9 2.4 7.5 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TMEM214 PF10151.9 CDJ42786.1 - 1.7 7.0 11.5 1.9 6.9 11.5 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator CDC45 PF02724.14 CDJ42786.1 - 1.8 6.8 14.6 1.8 6.8 14.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 CDJ42786.1 - 2 8.4 7.6 2.1 8.3 7.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ42786.1 - 8.5 5.1 9.8 8.8 5.0 9.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RRM_1 PF00076.22 CDJ42789.1 - 0.024 14.5 0.0 1 9.2 0.0 2.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RskA PF10099.9 CDJ42789.1 - 3.2 8.0 22.9 7 6.9 15.3 2.5 2 1 0 2 2 2 0 Anti-sigma-K factor rskA ABC2_membrane_2 PF12679.7 CDJ42791.1 - 0.28 10.4 0.0 0.28 10.4 0.0 3.4 3 1 0 3 3 3 0 ABC-2 family transporter protein PAM2 PF07145.15 CDJ42792.1 - 0.15 11.8 2.2 0.33 10.7 2.2 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region zf-CCCH PF00642.24 CDJ42792.1 - 0.23 11.4 1.5 0.97 9.4 1.5 2.1 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Dpy-30 PF05186.13 CDJ42793.1 - 4.9e-12 45.3 0.1 9.8e-12 44.4 0.1 1.5 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 CDJ42793.1 - 6.4e-08 32.8 0.0 0.097 12.8 0.0 3.4 3 0 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 CDJ42793.1 - 5.7e-06 26.8 2.7 0.00021 21.7 0.0 3.8 3 1 0 4 4 3 1 AAA domain AAA_18 PF13238.6 CDJ42793.1 - 8e-06 26.4 0.2 0.00034 21.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain SPX PF03105.19 CDJ42793.1 - 7.9e-05 22.7 12.8 0.0026 17.7 6.2 2.3 2 0 0 2 2 2 2 SPX domain AAA_28 PF13521.6 CDJ42793.1 - 0.00023 21.5 1.1 0.00023 21.5 1.1 3.4 4 0 0 4 4 2 1 AAA domain Mg_chelatase PF01078.21 CDJ42793.1 - 0.00096 18.6 0.1 0.002 17.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CDJ42793.1 - 0.0014 19.1 0.7 0.0014 19.1 0.7 3.9 3 1 1 4 4 3 1 AAA ATPase domain 6PF2K PF01591.18 CDJ42793.1 - 0.0019 17.5 0.0 2.1 7.6 0.0 2.8 3 0 0 3 3 2 2 6-phosphofructo-2-kinase AAA_22 PF13401.6 CDJ42793.1 - 0.0021 18.4 0.6 0.036 14.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 CDJ42793.1 - 0.0072 16.3 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 CDJ42793.1 - 0.0089 15.8 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 CDJ42793.1 - 0.011 16.1 0.0 0.044 14.2 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 CDJ42793.1 - 0.012 15.4 1.0 0.012 15.4 1.0 3.3 4 0 0 4 4 2 0 Cytidylate kinase NTPase_1 PF03266.15 CDJ42793.1 - 0.026 14.4 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 CDJ42793.1 - 0.026 14.7 0.0 0.026 14.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CDJ42793.1 - 0.031 14.0 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CDJ42793.1 - 0.049 13.4 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CDJ42793.1 - 0.052 13.5 0.3 0.11 12.4 0.0 1.7 2 0 0 2 2 1 0 Rad17 P-loop domain GlcNAc-1_reg PF18440.1 CDJ42793.1 - 0.076 13.3 0.1 4.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain KTI12 PF08433.10 CDJ42793.1 - 0.077 12.4 0.0 0.077 12.4 0.0 1.8 2 0 0 2 2 1 0 Chromatin associated protein KTI12 PRK PF00485.18 CDJ42793.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MID_MedPIWI PF18296.1 CDJ42793.1 - 0.097 12.4 0.0 0.097 12.4 0.0 2.6 2 1 0 2 2 1 0 MID domain of medPIWI SKI PF01202.22 CDJ42793.1 - 0.14 12.3 2.1 1.1 9.4 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase Presenilin PF01080.17 CDJ42793.1 - 0.24 10.1 15.4 0.22 10.2 8.7 2.3 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 CDJ42793.1 - 0.28 11.2 4.7 1.8 8.6 1.2 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region AAA_23 PF13476.6 CDJ42793.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.2 4 0 0 4 4 3 0 AAA domain DUF1645 PF07816.11 CDJ42793.1 - 1.4 9.4 30.3 1.5 9.3 0.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) DUF3807 PF12720.7 CDJ42793.1 - 2.3 8.5 19.2 2.5 8.3 6.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) DUF4569 PF15133.6 CDJ42793.1 - 2.3 7.8 13.2 1.4 8.6 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) Hydin_ADK PF17213.3 CDJ42793.1 - 2.3 8.4 37.9 6.6 7.0 12.3 3.9 3 1 0 3 3 3 0 Hydin Adenylate kinase-like domain CDC45 PF02724.14 CDJ42793.1 - 2.5 6.3 20.8 0.018 13.4 8.5 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF4667 PF15700.5 CDJ42793.1 - 2.8 8.0 20.9 0.18 11.9 7.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4667) EOS1 PF12326.8 CDJ42793.1 - 8.4 6.3 6.4 56 3.6 0.0 2.3 2 0 0 2 2 2 0 N-glycosylation protein DUF4201 PF13870.6 CDJ42794.1 - 5.4e-08 32.8 19.8 5.4e-08 32.8 19.8 4.4 2 2 2 4 4 4 1 Domain of unknown function (DUF4201) RNA_pol_Rpb2_6 PF00562.28 CDJ42795.1 - 8.6e-117 390.5 0.0 1.2e-116 390.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CDJ42795.1 - 4.4e-44 150.4 0.0 6.3e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 CDJ42795.1 - 1.8e-32 111.6 0.3 3.9e-32 110.5 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CDJ42795.1 - 7.3e-20 71.0 0.0 1.3e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CDJ42795.1 - 8.2e-20 70.8 0.0 1.7e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 CDJ42795.1 - 1.4e-15 57.4 0.0 2.8e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 CDJ42795.1 - 5.3e-06 26.9 1.7 1.5e-05 25.4 1.7 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 zn-ribbon_14 PF16503.5 CDJ42795.1 - 0.32 10.5 2.4 1.2 8.7 2.4 2.1 1 0 0 1 1 1 0 Zinc-ribbon Vps35 PF03635.17 CDJ42796.1 - 5.3e-245 815.4 0.0 3.2e-244 812.8 0.0 1.8 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Rtt106 PF08512.12 CDJ42798.1 - 1.8e-24 85.9 1.2 9.5e-24 83.6 0.1 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like POB3_N PF17292.2 CDJ42798.1 - 1.4e-23 83.1 0.3 1e-22 80.4 0.1 2.4 2 1 1 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 CDJ42798.1 - 1.8e-21 75.8 0.6 4.4e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) YL1 PF05764.13 CDJ42798.1 - 0.0053 16.9 14.2 0.013 15.7 14.2 1.5 1 0 0 1 1 1 1 YL1 nuclear protein RNA_pol_Rpc4 PF05132.14 CDJ42799.1 - 3.1e-13 50.4 0.1 3.1e-13 50.4 0.1 2.6 2 1 0 2 2 2 1 RNA polymerase III RPC4 AP2 PF00847.20 CDJ42800.1 - 6.9e-10 39.0 0.0 1.6e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 AP2 domain DUF3498 PF12004.8 CDJ42800.1 - 0.19 10.9 5.1 0.3 10.2 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) AP2 PF00847.20 CDJ42801.1 - 7e-12 45.4 0.2 1.9e-11 44.0 0.2 1.8 1 0 0 1 1 1 1 AP2 domain TFIIA PF03153.13 CDJ42801.1 - 0.72 9.8 7.3 1.3 8.9 7.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DivIC PF04977.15 CDJ42803.1 - 1.5e-05 24.7 0.6 2.8e-05 23.8 0.6 1.5 1 0 0 1 1 1 1 Septum formation initiator HALZ PF02183.18 CDJ42803.1 - 0.00034 20.8 2.0 0.00082 19.5 2.0 1.7 1 1 0 1 1 1 1 Homeobox associated leucine zipper TMF_DNA_bd PF12329.8 CDJ42803.1 - 0.00034 20.5 1.4 0.00053 19.9 1.4 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 CDJ42803.1 - 0.00039 20.4 1.9 0.0006 19.9 1.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 CDJ42803.1 - 0.00075 19.8 0.1 0.0016 18.7 0.1 1.6 1 1 0 1 1 1 1 TSC-22/dip/bun family DUF2968 PF11180.8 CDJ42803.1 - 0.00096 18.8 0.4 0.0013 18.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Nnf1 PF03980.14 CDJ42803.1 - 0.0013 19.1 0.3 0.0016 18.8 0.3 1.3 1 0 0 1 1 1 1 Nnf1 bZIP_2 PF07716.15 CDJ42803.1 - 0.0014 18.6 3.1 0.003 17.6 3.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Cnn_1N PF07989.11 CDJ42803.1 - 0.0015 18.7 0.2 0.002 18.2 0.2 1.4 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 ADIP PF11559.8 CDJ42803.1 - 0.0034 17.5 1.0 0.0059 16.7 1.0 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF4140 PF13600.6 CDJ42803.1 - 0.0059 17.0 0.2 0.0061 17.0 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) ZapB PF06005.12 CDJ42803.1 - 0.0067 16.8 3.0 0.011 16.1 3.0 1.4 1 0 0 1 1 1 1 Cell division protein ZapB DUF2730 PF10805.8 CDJ42803.1 - 0.0079 16.3 0.1 0.0084 16.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) GIT_CC PF16559.5 CDJ42803.1 - 0.0081 16.0 1.6 0.015 15.2 1.6 1.5 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3450 PF11932.8 CDJ42803.1 - 0.0087 15.4 1.2 0.013 14.8 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) JIP_LZII PF16471.5 CDJ42803.1 - 0.01 16.0 1.7 0.032 14.4 1.7 1.9 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Csm1_N PF18504.1 CDJ42803.1 - 0.012 16.0 1.9 0.02 15.2 1.9 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain FlaC_arch PF05377.11 CDJ42803.1 - 0.017 15.5 0.9 0.14 12.5 0.5 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 CDJ42803.1 - 0.023 13.6 0.4 0.022 13.6 0.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Phasin PF05597.11 CDJ42803.1 - 0.025 14.6 0.2 0.28 11.2 0.0 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4407 PF14362.6 CDJ42803.1 - 0.027 13.8 0.4 0.025 14.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 CDJ42803.1 - 0.039 14.5 2.9 0.042 14.4 2.9 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region Mto2_bdg PF12808.7 CDJ42803.1 - 0.046 14.0 0.4 0.11 12.8 0.4 1.6 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Shugoshin_N PF07558.11 CDJ42803.1 - 0.047 13.6 0.4 0.097 12.6 0.4 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Seryl_tRNA_N PF02403.22 CDJ42803.1 - 0.051 13.8 1.6 0.071 13.3 1.3 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain MbeD_MobD PF04899.12 CDJ42803.1 - 0.055 13.6 0.8 0.13 12.4 0.6 1.7 2 0 0 2 2 1 0 MbeD/MobD like YabA PF06156.13 CDJ42803.1 - 0.11 13.2 0.4 0.17 12.5 0.4 1.4 1 1 0 1 1 1 0 Initiation control protein YabA DUF1843 PF08898.10 CDJ42803.1 - 0.25 11.9 3.0 3.5 8.2 2.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) TRAF_BIRC3_bd PF16673.5 CDJ42803.1 - 0.28 11.0 3.1 0.24 11.2 1.4 1.6 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF4200 PF13863.6 CDJ42804.1 - 1.1e-14 54.9 3.3 1.1e-14 54.9 3.3 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) Med11 PF10280.9 CDJ42804.1 - 0.015 15.8 5.9 0.015 15.8 5.9 1.8 2 1 0 2 2 2 0 Mediator complex protein DUF768 PF05589.11 CDJ42804.1 - 0.47 10.5 2.2 1.8 8.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF768) HSBP1 PF06825.12 CDJ42804.1 - 1.1 9.2 0.0 1.1 9.2 0.0 3.1 2 2 0 2 2 2 0 Heat shock factor binding protein 1 Borrelia_P83 PF05262.11 CDJ42804.1 - 2.1 6.7 22.5 2.4 6.6 22.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Robl_LC7 PF03259.17 CDJ42806.1 - 3.1e-05 23.7 0.0 3.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CDJ42806.1 - 0.0039 17.1 0.0 0.004 17.0 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Arm PF00514.23 CDJ42807.1 - 1e-07 31.7 2.6 0.0055 16.7 0.1 4.1 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CDJ42807.1 - 0.0002 21.7 7.3 0.017 15.5 1.4 3.4 1 1 2 3 3 3 2 HEAT repeats Cnd1 PF12717.7 CDJ42807.1 - 0.00021 21.4 0.1 0.37 10.8 0.1 2.2 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDJ42807.1 - 0.032 14.5 2.4 11 6.6 0.1 3.4 3 1 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 CDJ42807.1 - 1.9 9.1 5.7 24 5.5 0.3 3.2 2 1 1 3 3 3 0 HEAT-like repeat SUIM_assoc PF16619.5 CDJ42809.1 - 7.6 6.7 13.9 1.2 9.3 4.0 3.5 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Rad50_zn_hook PF04423.14 CDJ42810.1 - 0.012 15.5 0.9 0.02 14.7 0.9 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif F-box PF00646.33 CDJ42811.1 - 0.0021 17.9 0.3 0.0054 16.6 0.3 1.7 1 0 0 1 1 1 1 F-box domain Radial_spoke PF04712.12 CDJ42813.1 - 9.6e-08 31.4 0.4 1.1e-07 31.2 0.4 1.3 1 1 0 1 1 1 1 Radial spokehead-like protein TSP_1 PF00090.19 CDJ42815.1 - 0.00046 20.4 1.8 0.0026 18.0 0.3 2.4 2 0 0 2 2 2 1 Thrombospondin type 1 domain Collagen PF01391.18 CDJ42815.1 - 0.89 9.4 49.2 0.15 11.9 13.4 5.1 4 1 0 4 4 4 0 Collagen triple helix repeat (20 copies) SUIM_assoc PF16619.5 CDJ42816.1 - 0.014 15.4 3.0 0.2 11.7 3.0 2.1 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 UPF0524 PF15823.5 CDJ42816.1 - 0.024 14.1 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 UPF0524 of C3orf70 RabGAP-TBC PF00566.18 CDJ42817.1 - 2.5e-41 141.7 4.6 3.8e-41 141.1 4.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain UBN_AB PF14075.6 CDJ42817.1 - 0.21 11.3 0.9 7.1 6.3 0.3 2.3 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Use1 PF09753.9 CDJ42817.1 - 0.63 9.7 5.3 0.92 9.2 4.5 1.7 1 1 0 1 1 1 0 Membrane fusion protein Use1 PHM7_cyt PF14703.6 CDJ42817.1 - 3.2 8.0 9.5 0.13 12.5 1.6 2.5 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Vta1 PF04652.16 CDJ42819.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Vta1 like NIF PF03031.18 CDJ42820.1 - 2.1e-31 108.8 0.0 2.4e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Mito_carr PF00153.27 CDJ42821.1 - 3.6e-28 97.3 0.2 1.5e-13 50.5 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3767 PF12597.8 CDJ42824.1 - 0.41 10.5 2.1 0.38 10.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) PolyA_pol PF01743.20 CDJ42825.1 - 1.4e-23 83.7 0.1 5.4e-23 81.8 0.0 2.2 3 0 0 3 3 3 1 Poly A polymerase head domain Kinesin PF00225.23 CDJ42827.1 - 1.2e-39 136.2 0.0 2.7e-36 125.2 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ42827.1 - 3.9e-09 36.6 0.0 1.1e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding MFS_1 PF07690.16 CDJ42828.1 - 1.3e-21 77.0 16.2 1.8e-21 76.5 16.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Presenilin PF01080.17 CDJ42828.1 - 1.5 7.5 3.8 2.5 6.8 3.8 1.3 1 0 0 1 1 1 0 Presenilin FOXP-CC PF16159.5 CDJ42829.1 - 0.67 10.6 4.2 2.1 9.1 0.8 3.5 3 1 1 4 4 4 0 FOXP coiled-coil domain YabA PF06156.13 CDJ42829.1 - 1.2 9.9 9.4 0.088 13.5 3.7 2.1 2 0 0 2 2 2 0 Initiation control protein YabA FliJ PF02050.16 CDJ42829.1 - 3.3 8.0 12.6 0.079 13.2 5.1 2.2 3 0 0 3 3 3 0 Flagellar FliJ protein CENP-Q PF13094.6 CDJ42829.1 - 10 6.3 14.3 65 3.7 11.0 2.8 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Glycophorin_A PF01102.18 CDJ42830.1 - 0.046 14.0 0.0 0.18 12.0 0.0 2.0 1 0 0 1 1 1 0 Glycophorin A RINGv PF12906.7 CDJ42832.1 - 1.1e-12 47.8 4.4 2.1e-12 46.9 4.4 1.5 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.26 CDJ42832.1 - 1.2e-10 41.5 0.3 3.2e-10 40.2 0.1 1.8 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ42832.1 - 2.3e-07 31.1 0.1 6.4e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain TPR_7 PF13176.6 CDJ42833.1 - 0.065 13.3 0.4 3 8.1 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIA PF03153.13 CDJ42834.1 - 0.063 13.3 41.1 0.076 13.0 41.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Atg14 PF10186.9 CDJ42834.1 - 0.085 11.9 18.7 0.11 11.6 18.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nop25 PF09805.9 CDJ42834.1 - 1.7 9.1 19.3 2.9 8.4 19.3 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Fmp27_WPPW PF10359.9 CDJ42834.1 - 2.2 7.0 18.7 2.7 6.8 18.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Mac PF12464.8 CDJ42834.1 - 2.7 8.3 7.2 4.7 7.5 6.7 1.7 1 1 0 1 1 1 0 Maltose acetyltransferase Cnn_1N PF07989.11 CDJ42834.1 - 4 7.7 20.0 0.47 10.6 13.5 2.4 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Paramyxo_ncap PF00973.19 CDJ42834.1 - 7.6 5.3 12.7 8.3 5.2 12.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein MAT1 PF06391.13 CDJ42834.1 - 8.2 6.2 25.7 10 5.8 25.7 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 adh_short_C2 PF13561.6 CDJ42835.1 - 6.2e-64 215.7 3.9 7.7e-64 215.5 3.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ42835.1 - 3.8e-57 192.9 2.3 4.7e-57 192.6 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDJ42835.1 - 6.5e-21 75.1 0.5 1.1e-20 74.3 0.5 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ42835.1 - 0.00015 21.3 0.4 0.00031 20.3 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 CDJ42835.1 - 0.041 13.6 0.3 0.088 12.6 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.10 CDJ42835.1 - 0.05 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Seadorna_Vp10 PF07322.11 CDJ42835.1 - 0.083 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus Vp10 PK PF00224.21 CDJ42836.1 - 4.8e-77 259.2 0.0 1.2e-36 126.3 0.5 3.1 3 0 0 3 3 3 3 Pyruvate kinase, barrel domain PK_C PF02887.16 CDJ42836.1 - 2.4e-12 47.1 0.0 1.6e-11 44.4 0.0 2.4 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain Spt20 PF12090.8 CDJ42836.1 - 0.45 10.1 2.7 0.83 9.2 2.7 1.3 1 0 0 1 1 1 0 Spt20 family Coatomer_g_Cpla PF16381.5 CDJ42837.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform Kinesin PF00225.23 CDJ42838.1 - 1.1e-85 287.5 0.0 1.9e-85 286.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ42838.1 - 9.9e-18 64.5 0.0 2.5e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding AIP3 PF03915.13 CDJ42838.1 - 0.0016 17.6 1.0 0.0016 17.6 1.0 1.5 2 0 0 2 2 2 1 Actin interacting protein 3 PH_17 PF18012.1 CDJ42838.1 - 0.0018 17.9 0.0 0.0046 16.6 0.0 1.6 1 0 0 1 1 1 1 PH domain Hs1pro-1_C PF07014.12 CDJ42838.1 - 0.021 14.3 0.0 4 6.8 0.0 2.3 2 0 0 2 2 2 0 Hs1pro-1 protein C-terminus CHASE3 PF05227.13 CDJ42838.1 - 0.25 11.2 8.1 2.9 7.8 0.1 2.4 2 0 0 2 2 2 0 CHASE3 domain AAA_22 PF13401.6 CDJ42838.1 - 0.89 9.8 2.9 23 5.2 0.1 3.1 3 0 0 3 3 3 0 AAA domain IP_trans PF02121.18 CDJ42839.1 - 9.9e-61 205.4 0.0 2.3e-41 142.0 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol transfer protein Oxysterol_BP PF01237.18 CDJ42839.1 - 9.8e-12 44.4 0.0 7.7e-10 38.1 0.0 2.3 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 CDJ42839.1 - 5.2e-11 43.0 0.0 9.8e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 PH domain YbhQ PF11076.8 CDJ42839.1 - 0.048 13.7 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ PH_11 PF15413.6 CDJ42839.1 - 0.2 12.1 0.2 3.8 8.0 0.2 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain DUF5336 PF17270.2 CDJ42839.1 - 3.8 7.1 6.6 0.92 9.1 2.5 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5336) SNF2_N PF00176.23 CDJ42840.1 - 5.6e-64 216.1 0.6 5.6e-64 216.1 0.6 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ42840.1 - 2.6e-19 69.6 0.0 2.6e-19 69.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_25 PF13481.6 CDJ42840.1 - 0.063 12.8 0.0 0.33 10.5 0.0 2.3 1 0 0 1 1 1 0 AAA domain CRAL_TRIO PF00650.20 CDJ42843.1 - 0.0047 16.7 0.2 0.0098 15.6 0.2 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain Ribosomal_60s PF00428.19 CDJ42843.1 - 0.13 12.8 3.3 0.25 12.0 3.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein TerD PF02342.18 CDJ42844.1 - 2.4e-06 27.2 0.0 4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 TerD domain Prefoldin_2 PF01920.20 CDJ42844.1 - 0.054 13.5 1.2 0.95 9.5 0.2 2.8 3 0 0 3 3 3 0 Prefoldin subunit Nup54 PF13874.6 CDJ42844.1 - 0.081 13.0 0.4 0.17 12.0 0.4 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DHR10 PF18595.1 CDJ42844.1 - 0.26 11.4 3.3 0.73 9.9 3.3 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Thioredoxin PF00085.20 CDJ42845.1 - 7.8e-44 147.9 0.3 1.4e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 CDJ42845.1 - 9.9e-07 28.9 0.5 0.006 16.7 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CDJ42845.1 - 2.4e-06 27.8 0.0 0.34 11.3 0.0 3.3 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.6 CDJ42845.1 - 0.0001 22.1 0.0 0.29 10.9 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.6 CDJ42845.1 - 0.00013 21.9 0.3 0.19 11.5 0.1 2.9 2 1 1 3 3 3 2 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 CDJ42845.1 - 0.00027 21.4 0.3 0.47 10.9 0.1 3.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 CDJ42845.1 - 0.00051 20.0 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain OST3_OST6 PF04756.13 CDJ42845.1 - 0.0034 16.8 0.0 1.7 7.9 0.0 2.6 2 1 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 CDJ42845.1 - 0.0051 16.7 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CDJ42845.1 - 0.013 15.4 0.1 6.7 6.6 0.0 2.2 2 0 0 2 2 2 0 AhpC/TSA family BNIP3 PF06553.12 CDJ42845.1 - 0.021 14.5 1.4 0.021 14.5 1.4 1.6 2 0 0 2 2 2 0 BNIP3 IL2 PF00715.17 CDJ42845.1 - 0.071 13.0 0.1 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Interleukin 2 SR-25 PF10500.9 CDJ42845.1 - 0.17 11.5 12.1 0.24 11.0 12.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ42845.1 - 0.23 12.1 11.6 0.48 11.1 11.6 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein LUC7 PF03194.15 CDJ42846.1 - 2e-48 165.2 0.8 2e-48 165.2 0.8 3.0 3 1 0 3 3 3 1 LUC7 N_terminus QRPTase_C PF01729.19 CDJ42846.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Spt20 PF12090.8 CDJ42848.1 - 0.0089 15.7 4.4 0.0089 15.7 4.4 4.4 3 1 0 3 3 3 2 Spt20 family MMR1 PF08505.10 CDJ42848.1 - 1.5 9.0 27.6 2.1 8.6 11.0 3.4 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein Pantoate_ligase PF02569.15 CDJ42849.1 - 8.6e-43 146.5 0.0 9.5e-33 113.5 0.0 2.5 1 1 1 2 2 2 2 Pantoate-beta-alanine ligase Acetyltransf_CG PF14542.6 CDJ42849.1 - 0.0021 18.1 0.0 0.0048 17.0 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 CDJ42849.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 CDJ42849.1 - 0.016 15.7 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ42849.1 - 0.018 15.2 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ42849.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SF-assemblin PF06705.11 CDJ42851.1 - 1.2e-18 67.4 12.0 7.5e-11 41.8 7.3 2.0 1 1 1 2 2 2 2 SF-assemblin/beta giardin Fes1 PF08609.10 CDJ42851.1 - 0.042 14.7 0.9 0.31 11.9 0.3 2.2 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 DUF1664 PF07889.12 CDJ42851.1 - 1 9.4 3.7 0.71 9.9 0.6 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) APC_N_CC PF16689.5 CDJ42852.1 - 0.016 15.2 5.5 0.1 12.7 0.0 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Herpes_UL36 PF03586.13 CDJ42852.1 - 0.041 13.2 8.9 0.86 8.9 0.8 2.3 1 1 1 2 2 2 0 Herpesvirus UL36 tegument protein TPR_2 PF07719.17 CDJ42852.1 - 0.17 12.1 0.6 34 4.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RPW8 PF05659.11 CDJ42852.1 - 0.45 10.2 7.8 0.26 11.0 1.5 3.0 3 1 1 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF664 PF04978.12 CDJ42852.1 - 0.62 10.5 8.8 0.039 14.4 1.8 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF664) PI3K_P85_iSH2 PF16454.5 CDJ42852.1 - 1.4 8.5 24.1 0.27 10.8 8.8 3.3 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Nsp1_C PF05064.13 CDJ42852.1 - 2.5 7.9 9.8 1.6 8.6 0.1 3.3 2 1 1 3 3 3 0 Nsp1-like C-terminal region Csm1_N PF18504.1 CDJ42852.1 - 2.9 8.3 16.5 0.39 11.1 0.2 4.7 3 1 1 4 4 4 0 Csm1 N-terminal domain TPR_14 PF13428.6 CDJ42852.1 - 3.4 8.7 6.4 27 6.0 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Spc7 PF08317.11 CDJ42852.1 - 4.7 6.0 30.2 1 8.2 5.0 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein Mt_ATP-synt_B PF05405.14 CDJ42852.1 - 4.8 6.8 16.9 0.24 11.0 3.7 2.7 2 1 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Fez1 PF06818.15 CDJ42852.1 - 5.9 7.3 25.8 62 4.0 24.8 2.7 1 1 1 2 2 2 0 Fez1 Sec20 PF03908.13 CDJ42852.1 - 6.6 6.7 10.2 0.62 10.0 0.7 3.4 2 2 1 3 3 3 0 Sec20 DUF4298 PF14131.6 CDJ42852.1 - 7 6.7 11.7 1.4 8.9 0.5 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4298) DUF724 PF05266.14 CDJ42852.1 - 7.8 6.3 21.8 11 5.9 1.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Thump_like PF18096.1 CDJ42853.1 - 0.1 12.5 2.3 1.4 8.9 1.2 2.9 1 1 1 2 2 2 0 THUMP domain-like NPV_P10 PF05531.12 CDJ42853.1 - 2 8.9 6.7 2.8 8.5 0.3 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Fez1 PF06818.15 CDJ42854.1 - 0.015 15.8 11.4 0.017 15.6 11.4 1.1 1 0 0 1 1 1 0 Fez1 TMF_TATA_bd PF12325.8 CDJ42854.1 - 0.076 13.2 11.5 0.13 12.5 4.0 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF641 PF04859.12 CDJ42854.1 - 0.23 11.8 7.7 0.26 11.6 7.2 1.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.12 CDJ42854.1 - 0.84 9.7 18.4 0.43 10.7 10.4 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 CDJ42854.1 - 1.1 8.5 10.1 1.2 8.4 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WASH-7_C PF14746.6 CDJ42854.1 - 7.7 6.2 7.4 2.5 7.7 1.9 1.9 1 1 1 2 2 2 0 WASH complex subunit 7, C-terminal TMF_TATA_bd PF12325.8 CDJ42855.1 - 0.0072 16.5 6.1 0.0072 16.5 6.1 2.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF4763 PF15960.5 CDJ42855.1 - 0.083 12.2 20.9 0.41 9.9 4.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Csm1_N PF18504.1 CDJ42855.1 - 1.1 9.6 11.2 0.09 13.1 2.3 3.0 2 0 0 2 2 2 0 Csm1 N-terminal domain Sec2p PF06428.11 CDJ42855.1 - 1.3 9.0 19.4 0.17 11.9 4.8 3.1 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p DUF3450 PF11932.8 CDJ42855.1 - 3.2 7.0 20.1 1.2 8.4 5.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) YabA PF06156.13 CDJ42855.1 - 4 8.1 8.7 11 6.7 2.9 2.6 2 0 0 2 2 2 0 Initiation control protein YabA DUF3972 PF13118.6 CDJ42855.1 - 5.6 7.4 9.4 7.3 7.0 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) AAA_lid_9 PF17871.1 CDJ42855.1 - 9.2 6.3 10.4 0.17 11.8 1.5 2.6 2 0 0 2 2 2 0 AAA lid domain zf-C2H2 PF00096.26 CDJ42858.1 - 0.00023 21.4 1.2 0.00046 20.5 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 CDJ42858.1 - 0.018 15.7 0.0 0.018 15.7 0.0 3.2 3 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 CDJ42858.1 - 0.037 14.9 0.8 0.087 13.7 0.8 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CDJ42858.1 - 0.058 13.3 0.1 0.092 12.7 0.1 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 CDJ42858.1 - 0.061 13.6 1.7 0.17 12.2 1.7 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF5320 PF17253.2 CDJ42858.1 - 0.093 13.8 1.2 0.093 13.8 1.2 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5320) XPA_N PF01286.18 CDJ42858.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 XPA protein N-terminal MCU PF04678.13 CDJ42858.1 - 2.1 8.4 9.0 1.1 9.3 0.9 2.7 3 0 0 3 3 3 0 Mitochondrial calcium uniporter Anillin_N PF16018.5 CDJ42860.1 - 0.054 14.1 9.1 0.4 11.3 0.5 3.8 3 0 0 3 3 3 0 Anillin N-terminus Ephrin_rec_like PF07699.13 CDJ42862.1 - 0.037 13.8 28.3 0.024 14.4 6.4 4.0 2 1 1 3 3 3 0 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 CDJ42865.1 - 0.014 15.1 3.7 0.014 15.1 3.7 16.9 8 6 7 18 18 18 0 Putative ephrin-receptor like RecT PF03837.14 CDJ42868.1 - 0.012 15.1 0.8 0.015 14.8 0.8 1.1 1 0 0 1 1 1 0 RecT family SlyX PF04102.12 CDJ42869.1 - 0.0016 19.0 0.9 0.0016 19.0 0.9 13.6 4 2 8 13 13 13 3 SlyX TolA_bind_tri PF16331.5 CDJ42869.1 - 0.0064 16.6 2.2 0.0064 16.6 2.2 11.7 9 3 2 11 11 11 3 TolA binding protein trimerisation EF-hand_7 PF13499.6 CDJ42870.1 - 2.3e-17 63.2 0.2 3.1e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ42870.1 - 4.7e-16 57.1 0.5 1.5e-07 30.4 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CDJ42870.1 - 1.3e-14 52.8 3.9 2.6e-07 30.0 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_9 PF14658.6 CDJ42870.1 - 2.2e-13 50.3 0.0 9.4e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDJ42870.1 - 4.6e-10 39.2 1.9 8.4e-05 22.3 0.3 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CDJ42870.1 - 9.4e-07 28.1 1.3 1.7e-05 24.1 0.3 2.7 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.13 CDJ42870.1 - 0.22 11.5 0.0 1.4 9.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) LNS2 PF08235.13 CDJ42871.1 - 9.3e-95 316.4 0.0 1.2e-94 316.0 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CDJ42871.1 - 6.1e-30 103.2 0.0 1.1e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 CDJ42871.1 - 1.7e-16 60.2 0.0 7.1e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Kinesin PF00225.23 CDJ42873.1 - 1.1e-40 139.6 22.5 1.1e-29 103.5 0.3 4.3 2 2 2 4 4 4 3 Kinesin motor domain Microtub_bd PF16796.5 CDJ42873.1 - 2.9e-17 63.0 0.0 2.9e-17 63.0 0.0 2.8 2 1 0 2 2 2 1 Microtubule binding DUF812 PF05667.11 CDJ42873.1 - 0.86 8.4 53.6 1.2 7.9 53.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Cgr1 PF03879.14 CDJ42874.1 - 0.066 13.6 21.3 0.14 12.5 21.3 1.5 1 0 0 1 1 1 0 Cgr1 family DUF4578 PF15147.6 CDJ42874.1 - 7.8 7.4 10.5 2 9.3 6.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) DUF3724 PF12521.8 CDJ42876.1 - 0.0025 17.6 2.8 36 4.6 0.1 5.5 3 0 0 3 3 3 3 Protein of unknown function (DUF3724) Peptidase_M48_N PF16491.5 CDJ42877.1 - 1.7e-55 187.7 2.1 1.8e-55 187.7 0.2 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CDJ42877.1 - 4.2e-40 137.6 0.0 6.1e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Spatacsin_C PF14649.6 CDJ42879.1 - 1.1e-07 31.3 5.7 0.00048 19.3 3.9 2.2 2 0 0 2 2 2 2 Spatacsin C-terminus Spond_N PF06468.13 CDJ42879.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Spondin_N DUF3452 PF11934.8 CDJ42880.1 - 0.011 15.3 0.2 0.014 15.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) MRP-S27 PF10037.9 CDJ42880.1 - 0.17 10.7 5.4 0.21 10.4 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 MukE PF04288.13 CDJ42883.1 - 0.0019 17.1 0.3 0.0019 17.1 0.3 2.4 3 0 0 3 3 3 1 MukE-like family SRP_SPB PF02978.19 CDJ42884.1 - 0.01 16.4 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 Signal peptide binding domain DUF1679 PF07914.11 CDJ42884.1 - 0.21 10.4 0.2 0.33 9.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) SUIM_assoc PF16619.5 CDJ42884.1 - 1.3 9.1 11.9 0.098 12.7 2.7 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Kinesin PF00225.23 CDJ42885.1 - 1.3e-83 280.8 0.0 1.3e-83 280.8 0.0 4.3 5 1 0 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ42885.1 - 1.1e-13 51.4 0.7 3.4e-12 46.5 0.0 3.5 2 1 0 2 2 2 1 Microtubule binding FHA PF00498.26 CDJ42885.1 - 1e-08 35.4 0.0 3e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 FHA domain Kinesin_assoc PF16183.5 CDJ42885.1 - 2.5e-05 24.5 0.2 2.5e-05 24.5 0.2 7.7 7 3 1 8 8 8 2 Kinesin-associated KIF1B PF12423.8 CDJ42885.1 - 0.078 13.4 0.0 0.66 10.5 0.0 2.7 1 0 0 1 1 1 0 Kinesin protein 1B Mito_carr PF00153.27 CDJ42886.1 - 7.7e-07 28.9 14.7 0.017 15.0 0.1 4.8 4 1 1 5 5 5 3 Mitochondrial carrier protein TFIIA PF03153.13 CDJ42886.1 - 0.00035 20.7 20.1 0.0022 18.1 2.6 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit ATG22 PF11700.8 CDJ42886.1 - 0.0018 17.0 0.1 0.0049 15.6 0.0 1.7 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like SPX PF03105.19 CDJ42886.1 - 0.011 15.6 7.3 0.019 14.9 4.9 1.9 2 0 0 2 2 2 0 SPX domain SARAF PF06682.12 CDJ42886.1 - 0.024 14.3 3.7 0.21 11.2 0.4 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4637 PF15470.6 CDJ42886.1 - 0.09 12.5 0.1 0.09 12.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) DUF4667 PF15700.5 CDJ42886.1 - 1.4 8.9 15.3 3.9 7.5 1.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) DUF4400 PF14348.6 CDJ42886.1 - 3 7.3 11.0 0.099 12.1 1.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4400) Med15 PF09606.10 CDJ42886.1 - 5.6 5.5 25.5 0.026 13.3 5.9 3.0 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal CCSAP PF15748.5 CDJ42886.1 - 8.6 6.4 11.7 17 5.4 0.1 3.1 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated zf-C2HC_2 PF13913.6 CDJ42887.1 - 1.2e-09 37.8 20.7 4e-07 29.8 6.8 2.8 2 0 0 2 2 2 2 zinc-finger of a C2HC-type RskA PF10099.9 CDJ42887.1 - 0.00036 20.9 3.5 0.00036 20.9 3.5 18.8 3 3 6 11 11 11 1 Anti-sigma-K factor rskA Herpes_LAMP2 PF06126.11 CDJ42887.1 - 3.4 6.2 5.1 6.4 5.3 5.1 1.4 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 AP2 PF00847.20 CDJ42888.1 - 4.4e-12 46.0 6.3 1.1e-06 28.8 0.2 6.5 8 1 0 8 8 8 2 AP2 domain Spt20 PF12090.8 CDJ42888.1 - 0.036 13.7 4.4 0.093 12.3 4.4 1.7 1 0 0 1 1 1 0 Spt20 family FmiP_Thoc5 PF09766.9 CDJ42889.1 - 0.48 9.6 7.9 0.75 9.0 7.9 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 UPF0242 PF06785.11 CDJ42889.1 - 1.6 8.8 9.5 2.2 8.4 9.2 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FtsH_ext PF06480.15 CDJ42890.1 - 0.053 13.9 0.1 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 FtsH Extracellular SR-25 PF10500.9 CDJ42890.1 - 0.3 10.7 4.5 0.42 10.2 4.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 CDJ42890.1 - 0.71 8.1 1.5 0.9 7.7 1.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-MYND PF01753.18 CDJ42891.1 - 2.7e-05 24.2 3.7 0.00013 22.0 3.7 2.3 1 0 0 1 1 1 1 MYND finger Shadoo PF14999.6 CDJ42891.1 - 0.033 14.3 9.1 0.61 10.2 1.9 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF3824 PF12868.7 CDJ42891.1 - 2.6 8.7 22.5 0.31 11.7 0.8 2.9 3 0 0 3 3 3 0 Domain of unknwon function (DUF3824) TFIIA PF03153.13 CDJ42891.1 - 2.9 7.8 27.1 0.23 11.4 22.3 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-HIT PF04438.16 CDJ42891.1 - 6 6.8 11.5 1.4 8.9 7.0 2.2 2 0 0 2 2 2 0 HIT zinc finger RskA PF10099.9 CDJ42891.1 - 7.9 6.7 22.2 2.1 8.6 6.8 2.4 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ42891.1 - 9 7.0 13.4 14 6.4 2.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein SR-25 PF10500.9 CDJ42893.1 - 5.4e-05 22.9 8.6 5.4e-05 22.9 8.6 5.1 5 1 1 6 6 6 2 Nuclear RNA-splicing-associated protein HTH_44 PF14641.6 CDJ42893.1 - 0.00081 19.8 0.0 0.0025 18.2 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 CDJ42894.1 - 1.5e-08 34.9 0.0 5.4e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 CDJ42894.1 - 1.3e-05 25.0 0.7 6.3e-05 22.8 0.0 2.5 3 0 0 3 3 3 1 Holliday-junction resolvase-like of SPT6 SH2_2 PF14633.6 CDJ42894.1 - 0.00035 20.1 0.0 0.00035 20.1 0.0 3.9 5 0 0 5 5 5 1 SH2 domain DUF2235 PF09994.9 CDJ42894.1 - 4.7 6.5 7.0 15 4.9 0.0 3.0 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) FAST_1 PF06743.15 CDJ42895.1 - 0.012 15.5 11.5 0.086 12.8 0.0 6.0 5 2 3 8 8 8 0 FAST kinase-like protein, subdomain 1 Ribonuc_P_40 PF08584.11 CDJ42896.1 - 5.5e-06 25.9 0.0 0.00054 19.3 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit AAA_21 PF13304.6 CDJ42897.1 - 6.8e-08 32.7 0.2 0.00041 20.3 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDJ42897.1 - 7.2e-06 26.6 0.3 6.2e-05 23.6 0.3 2.1 1 1 0 1 1 1 1 AAA domain Metallophos PF00149.28 CDJ42897.1 - 2.6e-05 24.8 0.0 5.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SMC_N PF02463.19 CDJ42897.1 - 0.00031 20.2 0.0 0.34 10.3 0.0 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CDJ42897.1 - 0.00071 19.8 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CDJ42897.1 - 0.03 14.1 0.0 0.084 12.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain HTH_55 PF18622.1 CDJ42897.1 - 0.05 13.9 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 RctB helix turn helix domain MukB PF04310.12 CDJ42897.1 - 0.095 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 MukB N-terminal ABC_tran PF00005.27 CDJ42897.1 - 0.12 12.9 0.1 22 5.6 0.1 2.5 2 0 0 2 2 2 0 ABC transporter TPR_2 PF07719.17 CDJ42898.1 - 2.2e-11 43.0 6.2 0.022 14.9 0.4 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ42898.1 - 1e-09 37.8 0.2 0.13 12.6 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ42898.1 - 2.6e-09 37.1 0.3 0.037 14.8 0.1 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ42898.1 - 3.5e-08 32.9 7.8 0.0076 16.0 0.3 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ42898.1 - 7.3e-08 32.4 0.7 0.00042 20.4 0.1 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ42898.1 - 2.3e-07 30.3 0.1 0.19 11.9 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ42898.1 - 1.2e-05 25.7 0.6 0.1 13.1 0.0 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ42898.1 - 7.3e-05 22.9 0.0 12 6.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ42898.1 - 0.00011 21.8 0.2 1.5 8.5 0.2 4.3 2 2 2 4 4 4 1 TPR repeat TPR_12 PF13424.6 CDJ42898.1 - 0.00018 21.7 0.9 1.6 9.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ42898.1 - 0.00048 20.6 0.2 3.7 8.4 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ42898.1 - 0.0016 19.0 2.7 0.057 14.1 0.2 3.7 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ42898.1 - 0.0027 17.0 0.0 0.0093 15.2 0.0 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ42898.1 - 0.0043 17.3 1.3 2 8.7 0.3 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 ABC1 PF03109.16 CDJ42901.1 - 2.6e-32 111.5 0.3 5.7e-32 110.4 0.2 1.6 1 1 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CDJ42901.1 - 0.012 15.2 0.0 0.042 13.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family AP_endonuc_2 PF01261.24 CDJ42902.1 - 2.3e-29 102.3 0.0 3.2e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF2124 PF09897.9 CDJ42902.1 - 0.14 12.0 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) Ribosomal_S19e PF01090.19 CDJ42903.1 - 2.9e-51 172.8 0.0 3.5e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.10 CDJ42903.1 - 0.0014 18.5 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain DTC PF18102.1 CDJ42904.1 - 2.5e-44 150.7 0.0 4.7e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Deltex C-terminal domain WWE PF02825.20 CDJ42904.1 - 6.2e-12 45.9 4.2 0.00012 22.5 0.0 3.6 3 0 0 3 3 3 3 WWE domain zf-RING_2 PF13639.6 CDJ42904.1 - 1.7e-06 28.3 8.2 2.2e-05 24.7 3.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CDJ42904.1 - 6.6e-05 22.6 4.9 0.00074 19.2 0.9 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 CDJ42904.1 - 0.00024 21.3 3.3 0.00024 21.3 3.3 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ42904.1 - 0.00028 20.7 4.4 0.00028 20.7 4.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ42904.1 - 0.003 17.5 3.4 0.003 17.5 3.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain PHD PF00628.29 CDJ42904.1 - 0.003 17.4 2.5 0.0096 15.8 2.5 1.9 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.6 CDJ42904.1 - 0.025 14.4 8.5 0.065 13.1 4.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ42904.1 - 0.037 14.1 4.1 0.062 13.3 1.5 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ42904.1 - 0.22 11.7 8.6 0.25 11.5 4.8 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Caudo_TAP PF02413.17 CDJ42904.1 - 1.3 9.2 7.5 0.75 9.9 5.1 1.9 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK Ribosomal_L30 PF00327.20 CDJ42906.1 - 1.1e-14 54.1 0.9 2.2e-14 53.1 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 CDJ42906.1 - 3.2e-14 52.9 18.3 3.2e-14 52.9 18.3 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L11_N PF03946.14 CDJ42907.1 - 2.3e-21 75.4 0.1 3.5e-21 74.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CDJ42907.1 - 9.5e-18 64.5 0.1 1.6e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF4476 PF14771.6 CDJ42907.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Chorein_N PF12624.7 CDJ42908.1 - 8.3e-30 103.3 0.0 8.3e-30 103.3 0.0 2.9 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CDJ42908.1 - 4.4e-16 59.4 1.3 1.2e-14 54.7 0.0 3.1 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 CDJ42908.1 - 1.3e-07 31.3 0.0 3.7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 CDJ42908.1 - 5.2e-05 23.5 0.0 0.00037 20.8 0.0 2.6 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 CDJ42908.1 - 0.26 11.1 2.3 25 4.6 0.1 3.5 3 0 0 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal Carboxyl_trans PF01039.22 CDJ42909.1 - 6.8e-154 513.1 0.0 3.1e-153 511.0 0.0 1.9 1 1 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CDJ42909.1 - 1.9e-52 177.8 0.0 3.6e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CDJ42909.1 - 2.5e-28 98.8 0.0 5.9e-28 97.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CDJ42909.1 - 4.9e-20 71.6 0.0 1.1e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ACC_central PF08326.12 CDJ42909.1 - 4.7e-17 61.5 0.1 4.5e-11 41.7 0.0 3.2 3 0 0 3 3 3 3 Acetyl-CoA carboxylase, central region Biotin_lipoyl PF00364.22 CDJ42909.1 - 1.7e-10 40.6 0.0 4.6e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 CDJ42909.1 - 8e-09 35.3 0.0 1.6e-07 31.0 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CDJ42909.1 - 4.8e-05 23.1 0.0 0.0008 19.2 0.0 2.9 2 0 0 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CDJ42909.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CDJ42909.1 - 0.00025 21.1 0.0 0.00059 19.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain DUF2857 PF11198.8 CDJ42909.1 - 0.045 13.5 1.0 0.16 11.7 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) LAL_C2 PF18603.1 CDJ42909.1 - 9.8 6.4 8.5 4.6 7.5 0.0 4.3 3 0 0 3 3 2 0 L-amino acid ligase C-terminal domain 2 Peptidase_S8 PF00082.22 CDJ42911.1 - 2e-33 116.0 2.2 2e-33 116.0 2.2 3.9 4 2 0 4 4 4 1 Subtilase family AAA_22 PF13401.6 CDJ42911.1 - 0.0015 18.8 4.3 0.12 12.6 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ42911.1 - 0.0041 17.5 12.9 0.0041 17.5 12.9 4.4 3 2 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 CDJ42911.1 - 0.0073 16.8 0.3 0.024 15.2 0.0 1.9 2 0 0 2 2 2 1 ABC transporter DUF2791 PF10923.8 CDJ42911.1 - 0.018 13.9 0.1 0.045 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) NACHT PF05729.12 CDJ42911.1 - 2 8.3 7.6 5.6 6.8 5.0 2.9 2 1 0 2 2 2 0 NACHT domain RAB3GAP2_N PF14655.6 CDJ42911.1 - 2.6 7.2 7.7 3.3 6.9 5.1 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus MCD PF05292.11 CDJ42911.1 - 4.5 6.8 6.1 13 5.2 6.1 1.8 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain SR-25 PF10500.9 CDJ42912.1 - 3.8e-05 23.4 43.3 3.8e-05 23.4 43.3 2.1 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Spore_GerAC PF05504.11 CDJ42912.1 - 0.12 12.6 7.0 0.16 12.2 7.0 1.1 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal DUF1168 PF06658.12 CDJ42912.1 - 0.45 10.3 46.1 0.44 10.4 30.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) O-antigen_lig PF13425.6 CDJ42912.1 - 3.7 6.2 6.1 4.1 6.1 6.1 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein PA26 PF04636.13 CDJ42912.1 - 5.1 5.9 13.2 6.5 5.6 13.2 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PHD PF00628.29 CDJ42913.1 - 6.7e-09 35.5 12.2 6.7e-09 35.5 12.2 2.9 3 0 0 3 3 2 1 PHD-finger zf-RING_2 PF13639.6 CDJ42913.1 - 4.8e-07 30.0 11.5 4.8e-07 30.0 11.5 2.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ42913.1 - 7.9e-06 25.6 7.7 7.9e-06 25.6 7.7 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ42913.1 - 0.0011 18.8 11.7 0.0011 18.8 11.7 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ42913.1 - 0.0034 17.2 9.8 0.0034 17.2 9.8 2.2 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CDJ42913.1 - 0.0043 17.3 6.0 0.0043 17.3 6.0 3.8 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDJ42913.1 - 0.0052 16.7 9.2 0.0052 16.7 9.2 2.9 2 1 1 3 3 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ42913.1 - 0.0062 16.3 11.6 0.0062 16.3 11.6 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CDJ42913.1 - 0.011 15.9 6.7 0.05 13.7 6.7 2.1 1 0 0 1 1 1 0 zinc RING finger of MSL2 Baculo_IE-1 PF05290.11 CDJ42913.1 - 0.014 15.3 1.7 0.014 15.3 1.7 1.9 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) PHD_2 PF13831.6 CDJ42913.1 - 0.045 13.3 7.1 0.11 12.1 7.1 1.7 1 0 0 1 1 1 0 PHD-finger zf-ANAPC11 PF12861.7 CDJ42913.1 - 0.72 9.9 12.8 2 8.5 1.0 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1364 PF07102.12 CDJ42913.1 - 1.7 8.5 9.8 1.6 8.6 3.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1364) DNA_methylase PF00145.17 CDJ42914.1 - 0.0016 17.9 0.0 0.47 9.7 0.0 2.1 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase PP2C PF00481.21 CDJ42915.1 - 2.3e-21 76.6 27.0 9.8e-18 64.7 1.9 4.8 3 3 1 4 4 4 3 Protein phosphatase 2C SR-25 PF10500.9 CDJ42915.1 - 5.6e-06 26.1 20.2 5.6e-06 26.1 20.2 7.1 4 1 2 6 6 6 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ42915.1 - 1.8 8.8 46.7 2.9 8.1 8.9 4.9 3 2 0 3 3 3 0 Anti-sigma-K factor rskA RAWUL PF16207.5 CDJ42916.1 - 0.13 12.9 1.2 0.15 12.7 1.2 1.3 1 1 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Androgen_recep PF02166.16 CDJ42916.1 - 1.5 7.6 9.9 1.5 7.6 9.9 1.1 1 0 0 1 1 1 0 Androgen receptor YjeF_N PF03853.15 CDJ42917.1 - 0.43 10.4 6.5 0.61 9.9 6.3 1.4 1 1 0 1 1 1 0 YjeF-related protein N-terminus BAF1_ABF1 PF04684.13 CDJ42917.1 - 0.51 9.3 11.8 0.62 9.1 11.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MAT1 PF06391.13 CDJ42917.1 - 0.62 9.9 9.8 0.85 9.4 9.8 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 IHABP4_N PF16174.5 CDJ42917.1 - 1 9.9 16.6 1.5 9.4 16.6 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Neur_chan_memb PF02932.16 CDJ42917.1 - 1.3 9.1 4.9 1.4 8.9 4.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ42917.1 - 2.1 8.3 25.4 2.4 8.1 25.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Coilin_N PF15862.5 CDJ42917.1 - 5.8 6.7 16.9 0.53 10.1 8.2 2.1 2 0 0 2 2 2 0 Coilin N-terminus CaKB PF03185.15 CDJ42918.1 - 0.12 12.1 4.6 0.15 11.7 4.6 1.1 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit AAT PF03417.16 CDJ42918.1 - 0.14 11.8 3.7 0.17 11.6 3.7 1.1 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase XPG_I_2 PF12813.7 CDJ42918.1 - 0.75 9.2 6.9 0.97 8.9 6.9 1.0 1 0 0 1 1 1 0 XPG domain containing Uso1_p115_C PF04871.13 CDJ42918.1 - 1.2 9.5 10.8 1.6 9.1 10.8 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TFIIA PF03153.13 CDJ42918.1 - 2.3 8.1 24.5 2.6 7.9 24.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ42918.1 - 2.6 6.2 19.8 2.8 6.1 19.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4636 PF15468.6 CDJ42919.1 - 0.0023 17.7 1.0 0.0023 17.7 1.0 2.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4636) Pep1_7 PF17232.2 CDJ42919.1 - 1.1 9.8 4.1 0.39 11.2 0.4 2.2 2 0 0 2 2 2 0 Elicitor peptide 1-7 DUF2975 PF11188.8 CDJ42920.1 - 0.005 16.7 4.5 0.08 12.8 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2975) YibE_F PF07907.11 CDJ42920.1 - 0.0055 16.2 0.5 0.0055 16.2 0.5 1.8 2 0 0 2 2 2 1 YibE/F-like protein DUF3021 PF11457.8 CDJ42920.1 - 0.017 15.5 0.4 0.03 14.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) DctQ PF04290.12 CDJ42920.1 - 0.033 14.1 1.2 0.033 14.1 1.2 1.9 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component E1-E2_ATPase PF00122.20 CDJ42920.1 - 0.2 11.2 4.4 0.073 12.6 0.9 1.8 2 0 0 2 2 2 0 E1-E2 ATPase DUF1345 PF07077.11 CDJ42920.1 - 0.53 10.0 8.3 0.31 10.7 5.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF202 PF02656.15 CDJ42920.1 - 3.3 8.2 13.2 6.2 7.3 2.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) AhpC-TSA PF00578.21 CDJ42921.1 - 4e-23 81.7 0.0 6.6e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ42921.1 - 4.1e-06 26.6 0.0 8.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDJ42921.1 - 7.6e-05 22.5 0.3 0.00014 21.6 0.3 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin zf-Di19 PF05605.12 CDJ42921.1 - 0.083 13.2 0.2 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding SecE PF00584.20 CDJ42922.1 - 4.5e-13 48.9 0.1 5.5e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex PAP_assoc PF03828.19 CDJ42923.1 - 0.008 16.4 1.4 0.077 13.2 1.4 2.5 1 1 0 1 1 1 1 Cid1 family poly A polymerase Metallothio_2 PF01439.18 CDJ42923.1 - 0.024 15.5 1.2 0.024 15.5 1.2 3.6 2 0 0 2 2 2 0 Metallothionein SARAF PF06682.12 CDJ42924.1 - 0.0024 17.6 0.1 0.0033 17.1 0.1 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis RAP1 PF07218.11 CDJ42924.1 - 6.7 4.9 6.6 8.8 4.5 6.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ion_trans PF00520.31 CDJ42925.1 - 1.5e-23 83.4 21.4 1.5e-20 73.4 0.3 2.8 2 1 1 3 3 3 2 Ion transport protein TFIIA PF03153.13 CDJ42925.1 - 0.0066 16.5 19.4 0.0066 16.5 19.4 3.2 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit CBP_BcsG PF11658.8 CDJ42925.1 - 0.059 11.8 8.5 0.49 8.7 0.3 2.4 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG PsaL PF02605.15 CDJ42925.1 - 0.065 12.9 0.1 0.9 9.2 0.0 2.7 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI V_ATPase_I PF01496.19 CDJ42925.1 - 0.33 8.8 5.9 0.94 7.3 5.9 1.7 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLN3 PF02487.17 CDJ42925.1 - 0.54 9.2 8.6 0.33 9.9 4.7 2.4 2 0 0 2 2 2 0 CLN3 protein RLL PF10036.9 CDJ42925.1 - 0.6 9.9 13.8 6.8 6.5 10.5 2.5 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein CPSF100_C PF13299.6 CDJ42925.1 - 0.8 9.9 7.9 1.7 8.8 5.0 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RICTOR_N PF14664.6 CDJ42925.1 - 1.7 7.6 7.4 0.45 9.5 4.0 1.7 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term EphA2_TM PF14575.6 CDJ42925.1 - 2.2 9.2 6.1 6.6 7.7 0.7 3.9 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Plasmodium_Vir PF05795.11 CDJ42925.1 - 4 6.7 4.0 3.7 6.9 2.3 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Gti1_Pac2 PF09729.9 CDJ42925.1 - 6.1 6.9 8.1 2.6 8.1 4.0 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family SID-1_RNA_chan PF13965.6 CDJ42925.1 - 8.4 4.7 6.9 3.8 5.8 2.4 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 NPR1_interact PF15699.5 CDJ42925.1 - 9.5 6.9 12.0 0.88 10.2 4.6 2.5 2 0 0 2 2 2 0 NPR1 interacting BING4CT PF08149.11 CDJ42926.1 - 6.7e-33 112.3 0.0 9.6e-30 102.2 0.0 3.2 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.32 CDJ42926.1 - 0.0057 17.5 0.0 2.3 9.3 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat SOBP PF15279.6 CDJ42926.1 - 1.2 9.7 6.4 0.18 12.4 1.8 1.8 2 0 0 2 2 2 0 Sine oculis-binding protein YL1 PF05764.13 CDJ42926.1 - 4.8 7.2 23.8 2.4 8.2 14.7 2.1 2 0 0 2 2 2 0 YL1 nuclear protein DUF3391 PF11871.8 CDJ42926.1 - 8.7 6.9 8.7 24 5.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF155 PF02582.14 CDJ42927.1 - 1.6e-43 148.9 0.0 3.1e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Carot_N PF09150.10 CDJ42928.1 - 0.015 15.1 0.1 0.023 14.6 0.1 1.2 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal tRNA-synt_1 PF00133.22 CDJ42929.1 - 1.3e-29 103.0 0.4 7e-13 47.7 0.0 5.6 4 1 0 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CDJ42929.1 - 1.9e-19 69.7 0.0 2.3e-07 29.9 0.0 4.1 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CDJ42929.1 - 3.4e-11 43.3 0.0 7.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 CDJ42929.1 - 2.3e-06 27.3 0.0 4.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.18 CDJ42929.1 - 0.18 10.7 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) SUIM_assoc PF16619.5 CDJ42929.1 - 1.5 8.9 10.9 0.21 11.7 0.6 3.9 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 ketoacyl-synt PF00109.26 CDJ42930.1 - 1.3e-49 169.1 1.0 1.8e-49 168.6 1.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 CDJ42930.1 - 0.00055 19.4 0.9 0.001 18.5 0.9 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF1180 PF06679.12 CDJ42930.1 - 0.055 13.9 1.6 0.15 12.5 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Ketoacyl-synt_C PF02801.22 CDJ42931.1 - 1.9e-27 95.6 0.2 2.2e-27 95.4 0.2 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain CactinC_cactus PF09732.9 CDJ42932.1 - 2.8e-54 182.4 8.4 2.8e-54 182.4 8.4 1.8 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 CDJ42932.1 - 1.5e-46 158.7 1.5 1.5e-46 158.7 1.5 2.7 3 0 0 3 3 3 1 Conserved mid region of cactin Sporozoite_P67 PF05642.11 CDJ42933.1 - 0.069 11.2 0.2 0.099 10.7 0.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GIDE PF12483.8 CDJ42933.1 - 0.16 11.3 0.0 0.43 10.0 0.0 1.6 1 0 0 1 1 1 0 E3 Ubiquitin ligase Ion_trans PF00520.31 CDJ42934.1 - 2.3e-09 36.8 14.1 6.2e-05 22.4 7.4 2.1 1 1 1 2 2 2 2 Ion transport protein Tmemb_170 PF10190.9 CDJ42934.1 - 0.084 13.2 2.3 0.24 11.8 2.3 1.7 1 0 0 1 1 1 0 Putative transmembrane protein 170 UPF0176_N PF17773.1 CDJ42935.1 - 1.7e-20 73.2 0.0 4.4e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Methyltransf_3 PF01596.17 CDJ42935.1 - 1.9e-20 73.0 0.0 5.8e-11 42.0 0.0 2.7 2 1 0 2 2 2 2 O-methyltransferase Rhodanese_C PF12368.8 CDJ42935.1 - 3.5e-11 43.3 12.0 9.9e-11 41.9 12.0 1.8 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 CDJ42935.1 - 7e-08 33.0 0.0 1.7e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_24 PF13578.6 CDJ42935.1 - 3.8e-06 27.9 0.0 1.7e-05 25.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain tRNA_Me_trans PF03054.16 CDJ42936.1 - 2.1e-78 263.6 0.0 9.4e-71 238.4 0.0 2.5 2 1 0 2 2 2 2 tRNA methyl transferase SufE PF02657.15 CDJ42936.1 - 0.0021 17.9 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 Fe-S metabolism associated domain ThiI PF02568.14 CDJ42936.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Rep_fac-A_3 PF08661.11 CDJ42937.1 - 6.7e-10 39.3 0.0 6.8e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 DUF150_C PF17384.2 CDJ42937.1 - 0.077 13.1 0.4 0.62 10.2 0.0 2.2 2 1 0 2 2 2 0 RimP C-terminal SH3 domain RR_TM4-6 PF06459.12 CDJ42938.1 - 3.3 7.4 12.5 8.2 6.2 12.5 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Carb_anhydrase PF00194.21 CDJ42939.1 - 1.6e-21 77.0 1.1 2.8e-13 50.0 0.0 3.0 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase SMC_ScpB PF04079.16 CDJ42939.1 - 0.18 11.4 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB MFS_1 PF07690.16 CDJ42940.1 - 1.8e-11 43.5 21.3 8.2e-09 34.8 22.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MAP17 PF15807.5 CDJ42940.1 - 0.059 13.6 3.5 0.063 13.5 0.5 2.2 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF3823 PF12866.7 CDJ42941.1 - 0.17 12.2 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) N-terminal domain TPR_1 PF00515.28 CDJ42942.1 - 3.7e-09 36.0 0.1 8e-07 28.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ42942.1 - 4.2e-07 29.6 0.0 0.0012 18.8 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat GFO_IDH_MocA PF01408.22 CDJ42942.1 - 5.4e-07 30.4 0.0 1.4e-06 29.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TPR_8 PF13181.6 CDJ42942.1 - 9.9e-07 28.5 0.0 0.00031 20.7 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ42942.1 - 1.8e-05 25.0 0.1 0.1 12.9 0.0 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ42942.1 - 0.0018 18.9 0.2 9.2 7.4 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ42942.1 - 0.0028 17.6 0.0 0.83 9.8 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ42942.1 - 0.034 14.7 0.0 0.11 13.0 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ42942.1 - 0.06 13.0 0.1 2.1 8.1 0.1 2.8 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.6 CDJ42942.1 - 0.12 13.1 0.0 0.33 11.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat tRNA-synt_2d PF01409.20 CDJ42943.1 - 0.57 9.6 2.6 3.6 7.0 1.1 2.1 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Adaptin_N PF01602.20 CDJ42944.1 - 2.1e-37 128.9 0.0 1.4e-20 73.4 0.0 2.3 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 CDJ42944.1 - 6.6e-29 101.0 0.2 4.8e-27 95.0 0.0 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 CDJ42944.1 - 1.1e-14 54.5 0.1 2.5e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 CDJ42944.1 - 1.5e-06 28.5 6.3 0.0078 16.6 0.7 4.0 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 CDJ42944.1 - 0.00015 21.7 5.0 0.018 15.3 0.2 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 CDJ42944.1 - 0.019 15.5 3.9 3.2 8.4 0.0 4.6 4 0 0 4 4 4 0 HEAT-like repeat Arm PF00514.23 CDJ42944.1 - 0.035 14.2 1.4 0.67 10.1 0.2 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat EBP50_C PF09007.11 CDJ42944.1 - 0.39 11.7 3.9 0.79 10.7 3.9 1.4 1 0 0 1 1 1 0 EBP50, C-terminal DUF3112 PF11309.8 CDJ42945.1 - 0.53 9.7 2.0 1 8.7 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Macoilin PF09726.9 CDJ42945.1 - 0.77 8.2 35.4 0.14 10.7 16.9 2.2 2 0 0 2 2 2 0 Macoilin family CDC27 PF09507.10 CDJ42945.1 - 1.9 7.8 30.1 0.43 9.9 12.7 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MMU163 PF17119.5 CDJ42945.1 - 5.5 6.1 7.6 17 4.5 7.6 1.7 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Apt1 PF10351.9 CDJ42945.1 - 6.6 5.5 28.2 0.16 10.8 15.5 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain SOBP PF15279.6 CDJ42945.1 - 8.2 6.9 13.9 1.1 9.8 5.7 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein RRM_1 PF00076.22 CDJ42946.1 - 4.9e-26 90.3 0.0 1.8e-16 59.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ42946.1 - 0.11 12.7 0.0 1 9.5 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif Proteasome PF00227.26 CDJ42947.1 - 2e-32 112.2 0.0 2.3e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit GAS PF13851.6 CDJ42948.1 - 0.002 17.5 12.1 0.002 17.5 12.1 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Spc29 PF17082.5 CDJ42948.1 - 0.033 14.0 0.6 0.033 14.0 0.6 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 GCD14 PF08704.10 CDJ42948.1 - 0.093 12.4 4.3 0.14 11.8 4.3 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Prominin PF05478.11 CDJ42948.1 - 0.11 10.4 4.7 0.18 9.7 4.7 1.3 1 0 0 1 1 1 0 Prominin DAG_kinase_N PF14513.6 CDJ42948.1 - 0.31 11.2 7.5 0.13 12.5 4.8 1.7 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DUF3584 PF12128.8 CDJ42948.1 - 0.37 8.2 15.8 0.013 13.1 10.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Herpes_UL6 PF01763.16 CDJ42948.1 - 0.96 7.9 9.6 0.44 9.0 7.9 1.3 1 1 0 1 1 1 0 Herpesvirus UL6 like ALMT PF11744.8 CDJ42948.1 - 1.2 7.8 6.8 1.5 7.6 6.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4600 PF15372.6 CDJ42948.1 - 5 7.6 15.8 15 6.0 15.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Sas6_CC PF18594.1 CDJ42948.1 - 5 7.0 15.3 0.18 11.6 4.1 2.6 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain V_ATPase_I PF01496.19 CDJ42948.1 - 5.2 4.8 6.4 6.2 4.6 6.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMEM192 PF14802.6 CDJ42948.1 - 7.7 5.5 7.9 12 4.9 1.5 2.2 2 0 0 2 2 2 0 TMEM192 family SpoIIP PF07454.11 CDJ42949.1 - 4.9 6.5 11.4 6.2 6.2 6.2 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Sybindin PF04099.12 CDJ42950.1 - 4.9e-29 101.1 0.0 1e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 Sybindin-like family Sec16_C PF12931.7 CDJ42950.1 - 2.8e-15 56.8 6.6 2.8e-15 56.8 6.6 3.4 2 2 0 2 2 2 1 Sec23-binding domain of Sec16 Sedlin_N PF04628.13 CDJ42950.1 - 1.7e-05 24.9 0.0 4.4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Hema_stalk PF08720.10 CDJ42954.1 - 0.22 11.2 0.4 0.52 10.0 0.4 1.6 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk RT_RNaseH PF17917.1 CDJ42960.1 - 1.3e-28 99.4 0.0 1.8e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ42960.1 - 4e-28 97.4 0.0 6.8e-28 96.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CDJ42960.1 - 0.0092 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like FAM92 PF06730.11 CDJ42960.1 - 0.051 13.0 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 FAM92 protein Pinin_SDK_memA PF04696.13 CDJ42962.1 - 1.5e-18 67.1 12.0 1.5e-18 67.1 12.0 1.5 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region SOGA PF11365.8 CDJ42962.1 - 0.07 14.3 7.2 23 6.2 1.7 3.3 2 1 1 3 3 3 0 Protein SOGA DAGK_acc PF00609.19 CDJ42963.1 - 1.7e-30 106.5 0.0 6.3e-15 55.9 0.0 2.8 2 1 1 3 3 3 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CDJ42963.1 - 9.4e-22 77.0 0.0 1.3e-14 53.9 0.0 2.7 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 CDJ42963.1 - 1.4e-09 37.6 30.6 3.1e-07 30.2 5.1 2.8 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Coilin_N PF15862.5 CDJ42963.1 - 0.25 11.1 20.4 22 4.9 3.4 5.3 5 1 0 5 5 5 0 Coilin N-terminus EF-hand_1 PF00036.32 CDJ42964.1 - 6e-33 109.9 14.3 5.2e-09 35.0 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ42964.1 - 8.4e-29 99.8 7.6 5.6e-14 52.4 2.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ42964.1 - 3.3e-27 92.1 7.4 5e-09 35.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDJ42964.1 - 2e-20 72.4 14.2 3.8e-13 49.1 0.9 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CDJ42964.1 - 2.3e-14 53.4 0.1 3.9e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ42964.1 - 1.2e-13 49.8 12.7 0.00023 20.5 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 CDJ42964.1 - 6.4e-05 22.9 4.0 0.46 10.5 0.4 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SurA_N_3 PF13624.6 CDJ42964.1 - 0.00057 19.7 1.0 0.27 11.0 0.2 2.1 1 1 1 2 2 2 2 SurA N-terminal domain Dockerin_1 PF00404.18 CDJ42964.1 - 0.003 17.7 0.6 0.13 12.4 0.1 2.4 2 1 0 2 2 2 1 Dockerin type I domain DUF853 PF05872.12 CDJ42964.1 - 0.0061 15.2 0.2 0.63 8.6 0.0 2.0 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF853) SurA_N_2 PF13623.6 CDJ42964.1 - 0.0063 16.4 0.2 1.1 9.1 0.1 2.2 2 0 0 2 2 2 1 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 CDJ42964.1 - 0.035 14.4 0.0 6.6 7.1 0.1 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 CDJ42964.1 - 0.044 14.1 0.5 2.9 8.3 0.1 2.6 1 1 2 3 3 3 0 EF-hand domain Staphylokinase PF02821.16 CDJ42964.1 - 0.053 14.0 0.3 0.26 11.7 0.3 2.1 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family Sigma54_CBD PF04963.13 CDJ42964.1 - 0.064 13.1 0.1 0.084 12.7 0.1 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain Acetyltransf_11 PF13720.6 CDJ42964.1 - 0.08 13.4 0.1 0.91 10.0 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Phage_TAC_12 PF12363.8 CDJ42964.1 - 0.1 13.1 1.8 0.53 10.7 0.3 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC HTH_40 PF14493.6 CDJ42964.1 - 0.12 12.8 1.7 2.7 8.5 0.1 2.3 1 1 0 2 2 2 0 Helix-turn-helix domain DUF3349 PF11829.8 CDJ42964.1 - 0.16 12.8 1.9 7.6 7.4 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3349) MgtE_N PF03448.17 CDJ42964.1 - 0.49 11.0 2.9 0.43 11.2 0.3 2.2 3 0 0 3 3 2 0 MgtE intracellular N domain SHOCT PF09851.9 CDJ42964.1 - 1 9.2 0.1 1 9.2 0.1 3.5 4 0 0 4 4 4 0 Short C-terminal domain Plasmodium_Vir PF05795.11 CDJ42965.1 - 3.8 6.8 7.6 0.22 10.9 0.1 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein FHA PF00498.26 CDJ42966.1 - 8.2e-09 35.7 0.0 2.2e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ42966.1 - 1e-05 25.8 0.0 2.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain HBS1_N PF08938.10 CDJ42966.1 - 0.065 13.6 0.8 0.15 12.4 0.8 1.6 1 0 0 1 1 1 0 HBS1 N-terminus Methyltransf_25 PF13649.6 CDJ42967.1 - 6e-13 49.3 0.1 1.3e-12 48.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ42967.1 - 1.2e-11 45.1 0.0 2.2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ42967.1 - 3.5e-10 40.0 0.0 5.5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ42967.1 - 1.8e-08 35.1 0.0 3.6e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ42967.1 - 0.00017 21.4 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ42967.1 - 0.00058 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ42967.1 - 0.017 14.7 0.3 0.063 12.8 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase small domain NodS PF05401.11 CDJ42967.1 - 0.035 13.7 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) TehB PF03848.14 CDJ42967.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.20 CDJ42967.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 CDJ42967.1 - 0.2 12.0 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Vps39_2 PF10367.9 CDJ42968.1 - 0.026 15.0 0.5 0.057 13.9 0.5 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 HTH_11 PF08279.12 CDJ42969.1 - 1.3 9.0 4.8 13 5.8 0.1 3.5 3 0 0 3 3 3 0 HTH domain Tubulin PF00091.25 CDJ42970.1 - 1.2e-65 221.4 0.0 1.8e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ42970.1 - 2.3e-29 102.1 0.0 4.1e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDJ42970.1 - 2.9e-05 24.4 0.0 6.1e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CDJ42970.1 - 0.0038 16.5 0.0 0.0068 15.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin like SBF2 PF12335.8 CDJ42971.1 - 0.063 12.9 1.6 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Myotubularin protein CdiI_2 PF18593.1 CDJ42972.1 - 0.31 11.7 1.1 1e+02 3.7 0.0 3.7 4 0 0 4 4 4 0 CdiI immunity protein DUF5336 PF17270.2 CDJ42975.1 - 1.1e-07 31.7 8.2 1.2 8.8 0.1 7.2 8 0 0 8 8 8 4 Family of unknown function (DUF5336) Ribosomal_TL5_C PF14693.6 CDJ42975.1 - 0.00087 19.6 2.6 36 4.8 0.0 5.0 6 0 0 6 6 6 0 Ribosomal protein TL5, C-terminal domain HisG PF01634.18 CDJ42975.1 - 0.0045 17.0 0.1 20 5.1 0.0 4.3 5 0 0 5 5 5 2 ATP phosphoribosyltransferase NiFe_hyd_SSU_C PF14720.6 CDJ42975.1 - 0.099 13.0 0.1 38 4.8 0.0 2.9 2 0 0 2 2 2 0 NiFe/NiFeSe hydrogenase small subunit C-terminal Bac_GDH PF05088.12 CDJ42975.1 - 8.7 3.7 15.2 1.1 6.6 0.1 3.1 3 0 0 3 3 3 0 Bacterial NAD-glutamate dehydrogenase Brix PF04427.18 CDJ42977.1 - 2.5e-33 115.8 0.1 3.5e-33 115.3 0.1 1.2 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.13 CDJ42977.1 - 1 9.3 14.5 1.4 8.8 14.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mon1 PF03164.14 CDJ42978.1 - 7e-33 114.3 0.0 8.5e-23 81.1 0.0 2.7 1 1 1 2 2 2 2 Trafficking protein Mon1 TraF_2 PF13729.6 CDJ42978.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein CcdA PF07362.12 CDJ42978.1 - 1.6 9.2 5.2 24 5.5 0.0 3.3 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA STI1 PF17830.1 CDJ42980.1 - 0.052 13.5 0.6 0.083 12.8 0.6 1.3 1 0 0 1 1 1 0 STI1 domain Tic110 PF16940.5 CDJ42980.1 - 0.46 8.9 22.0 0.54 8.7 22.0 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter ubiquitin PF00240.23 CDJ42982.1 - 7.1e-07 28.9 0.1 1.7e-06 27.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CDJ42982.1 - 4.2e-05 23.9 0.0 0.00022 21.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 CDJ42982.1 - 0.033 14.0 0.1 0.15 11.9 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PI3K_rbd PF00794.18 CDJ42982.1 - 0.12 12.6 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain UN_NPL4 PF11543.8 CDJ42982.1 - 0.16 12.5 0.0 0.2 12.1 0.0 1.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 GMC_oxred_N PF00732.19 CDJ42983.1 - 1.8e-22 80.1 0.2 8.5e-15 54.9 0.0 3.3 2 1 1 3 3 3 3 GMC oxidoreductase TFIIA PF03153.13 CDJ42983.1 - 0.65 9.9 39.4 0.19 11.7 1.4 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 CDJ42983.1 - 4.9 7.5 15.9 3.7 7.9 2.1 3.2 3 0 0 3 3 3 0 Enhancer of polycomb-like GMC_oxred_N PF00732.19 CDJ42984.1 - 8.2e-14 51.7 0.1 8.7e-14 51.6 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CDJ42985.1 - 2.3e-12 47.7 4.8 5.2e-08 33.5 1.7 2.6 1 1 0 2 2 2 2 GMC oxidoreductase UPF0564 PF10595.9 CDJ42985.1 - 5e-05 22.5 5.5 5.9e-05 22.3 5.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 Mucin PF01456.17 CDJ42985.1 - 0.0024 17.9 15.3 0.0037 17.3 15.3 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Macoilin PF09726.9 CDJ42985.1 - 0.0074 14.9 22.1 0.01 14.4 22.1 1.2 1 0 0 1 1 1 1 Macoilin family Alpha_GJ PF03229.13 CDJ42985.1 - 0.03 14.9 8.8 0.05 14.1 8.8 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J BAF1_ABF1 PF04684.13 CDJ42985.1 - 0.061 12.4 10.1 0.073 12.1 10.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ndc1_Nup PF09531.10 CDJ42985.1 - 0.36 9.5 20.4 0.44 9.2 20.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TAF4 PF05236.14 CDJ42985.1 - 0.63 9.7 17.9 0.03 14.1 10.7 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Hid1 PF12722.7 CDJ42985.1 - 0.71 7.9 14.7 0.85 7.7 14.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spt20 PF12090.8 CDJ42985.1 - 0.76 9.3 33.8 0.61 9.7 17.4 2.3 2 0 0 2 2 2 0 Spt20 family GREB1 PF15782.5 CDJ42985.1 - 1.3 6.0 17.9 1.4 5.9 17.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Kinesin_assoc PF16183.5 CDJ42985.1 - 2.2 8.4 6.0 3.9 7.6 6.0 1.5 1 0 0 1 1 1 0 Kinesin-associated WD40 PF00400.32 CDJ42986.1 - 1.5e-18 66.8 27.6 8.6e-05 23.2 0.1 8.7 8 1 0 8 8 8 4 WD domain, G-beta repeat PRP4 PF08799.11 CDJ42986.1 - 5.3e-12 45.1 1.0 9.6e-12 44.2 1.0 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 CDJ42986.1 - 1.5e-06 28.4 0.4 0.76 10.1 0.1 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain SUIM_assoc PF16619.5 CDJ42986.1 - 0.082 13.0 0.0 0.082 13.0 0.0 5.7 5 1 1 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 MRP-L27 PF09809.9 CDJ42987.1 - 6.9e-12 45.2 0.0 7.5e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 RRM_1 PF00076.22 CDJ42988.1 - 0.001 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MREG PF15812.5 CDJ42988.1 - 0.029 14.7 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 Melanoregulin Sugar_tr PF00083.24 CDJ42989.1 - 1e-10 41.1 2.6 1.2e-10 40.9 2.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ42989.1 - 1.9e-08 33.6 22.6 2.4e-08 33.3 22.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CDJ42989.1 - 0.0082 14.5 0.0 0.012 13.9 0.0 1.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Ribosomal_60s PF00428.19 CDJ42989.1 - 0.12 13.0 5.5 0.24 12.0 5.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein SpoU_methylase PF00588.19 CDJ42991.1 - 8.1e-09 35.8 0.0 3.4e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 SpoU rRNA Methylase family TFIIA PF03153.13 CDJ42991.1 - 0.002 18.2 10.1 0.0033 17.5 10.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ42991.1 - 0.43 10.9 12.7 0.77 10.0 12.7 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Raftlin PF15250.6 CDJ42991.1 - 0.6 8.8 4.4 1.2 7.8 4.4 1.4 1 0 0 1 1 1 0 Raftlin DEK_C PF08766.11 CDJ42992.1 - 4.3e-06 26.6 0.7 7.8e-06 25.7 0.7 1.5 1 0 0 1 1 1 1 DEK C terminal domain Adaptin_binding PF10199.9 CDJ42992.1 - 0.0048 17.5 10.5 0.0082 16.7 10.5 1.3 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Sporozoite_P67 PF05642.11 CDJ42992.1 - 0.01 14.0 1.0 0.0098 14.0 1.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DDHD PF02862.17 CDJ42992.1 - 0.036 14.2 1.4 0.037 14.2 1.4 1.1 1 0 0 1 1 1 0 DDHD domain DUF4175 PF13779.6 CDJ42992.1 - 0.059 11.3 8.2 0.071 11.0 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med8 PF10232.9 CDJ42992.1 - 0.075 12.6 6.4 0.1 12.1 6.4 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF4611 PF15387.6 CDJ42992.1 - 0.13 12.5 8.7 0.22 11.8 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CobT PF06213.12 CDJ42992.1 - 0.18 11.2 12.7 0.22 10.9 12.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2052 PF09747.9 CDJ42992.1 - 0.21 11.7 11.5 0.27 11.4 11.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pkinase_fungal PF17667.1 CDJ42992.1 - 0.24 10.2 5.3 0.28 9.9 5.3 1.0 1 0 0 1 1 1 0 Fungal protein kinase Folliculin PF11704.8 CDJ42992.1 - 0.29 11.0 3.9 0.42 10.5 3.9 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport RP-C_C PF11800.8 CDJ42992.1 - 0.3 11.2 7.8 0.4 10.7 7.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region UBN_AB PF14075.6 CDJ42992.1 - 0.31 10.7 9.3 0.4 10.4 9.3 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Het-C PF07217.11 CDJ42992.1 - 0.33 9.4 5.0 0.43 9.1 5.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C TLP-20 PF06088.11 CDJ42992.1 - 0.37 10.7 5.0 0.63 9.9 5.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SAPS PF04499.15 CDJ42992.1 - 0.4 9.4 10.5 0.45 9.3 10.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 CDJ42992.1 - 0.41 9.4 3.9 0.42 9.3 3.9 1.1 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 CDJ42992.1 - 0.47 10.8 11.3 0.59 10.4 11.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RRN3 PF05327.11 CDJ42992.1 - 0.51 8.8 4.5 0.56 8.7 4.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 CDJ42992.1 - 0.58 10.0 14.7 0.66 9.8 14.1 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region RR_TM4-6 PF06459.12 CDJ42992.1 - 0.9 9.3 13.1 1 9.2 13.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ42992.1 - 1.2 9.0 6.2 1.6 8.7 6.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF3810 PF12725.7 CDJ42992.1 - 1.4 8.2 3.4 1.8 7.8 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) CDC45 PF02724.14 CDJ42992.1 - 1.5 7.0 10.7 1.7 6.8 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 CDJ42992.1 - 2.7 6.9 17.0 3.2 6.6 17.0 1.1 1 0 0 1 1 1 0 Paf1 ALMT PF11744.8 CDJ42992.1 - 3.1 6.5 8.8 3.7 6.3 8.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter RNA_pol_Rpc4 PF05132.14 CDJ42992.1 - 9.4 6.7 12.5 13 6.2 11.9 1.6 1 1 0 1 1 1 0 RNA polymerase III RPC4 Rad51 PF08423.11 CDJ42993.1 - 1.4e-52 178.5 0.1 1.4e-51 175.2 0.0 2.1 1 1 2 3 3 3 1 Rad51 HHH_5 PF14520.6 CDJ42993.1 - 9.1e-05 23.0 0.7 0.00018 22.0 0.7 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain SR-25 PF10500.9 CDJ42994.1 - 0.0036 17.0 12.4 0.0036 17.0 12.4 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 CDJ42994.1 - 0.53 8.8 9.4 0.024 13.2 3.1 1.8 2 0 0 2 2 2 0 Macoilin family NAM-associated PF14303.6 CDJ42994.1 - 2.6 8.7 8.2 0.18 12.5 2.2 2.0 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain DUF3338 PF11819.8 CDJ42994.1 - 4.9 7.1 8.4 6.9 6.7 2.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3338) DUF3446 PF11928.8 CDJ42994.1 - 7.2 7.0 19.1 2.7 8.4 14.3 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF4614 PF15391.6 CDJ42994.1 - 10 6.1 13.1 0.67 9.9 5.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4614) WD40 PF00400.32 CDJ42995.1 - 5.9e-08 33.3 3.0 0.032 15.1 0.0 6.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ42995.1 - 8.6e-07 29.2 0.0 0.0019 18.5 0.0 4.6 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CDJ42995.1 - 0.013 15.5 0.5 11 6.1 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat ANAPC1 PF12859.7 CDJ42995.1 - 0.75 10.4 7.4 3.7 8.1 6.9 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Peptidase_S64 PF08192.11 CDJ42995.1 - 2 6.8 6.9 4 5.8 6.9 1.4 1 0 0 1 1 1 0 Peptidase family S64 Sporozoite_P67 PF05642.11 CDJ42995.1 - 5 5.1 18.4 0.14 10.3 10.0 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen tRNA-synt_2 PF00152.20 CDJ42998.1 - 1.4e-78 264.2 0.0 1.8e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ42998.1 - 1.7e-10 40.7 0.0 3.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDJ42998.1 - 3e-07 30.2 0.0 0.00012 21.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) UCH PF00443.29 CDJ42999.1 - 5.1e-10 39.3 5.5 5.1e-10 39.3 5.5 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Radical_SAM PF04055.21 CDJ43000.1 - 9.5e-18 65.1 0.0 3.2e-17 63.4 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Radical_SAM_C PF16199.5 CDJ43000.1 - 1.4e-17 63.5 0.0 3.1e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Glyco_transf_9 PF01075.17 CDJ43000.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Acetyltransf_1 PF00583.25 CDJ43000.1 - 0.068 13.4 0.1 0.23 11.7 0.1 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ43000.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Adeno_E3_CR2 PF02439.15 CDJ43001.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RRM_1 PF00076.22 CDJ43005.1 - 1.4e-27 95.2 0.1 6.7e-16 57.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ43005.1 - 2.4e-06 27.6 0.2 0.0016 18.5 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ43005.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif tRNA-synt_2c PF01411.19 CDJ43006.1 - 2.5e-198 660.1 0.0 3e-198 659.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CDJ43006.1 - 1.1e-14 54.2 0.1 2.6e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CDJ43006.1 - 8.5e-06 26.2 1.7 2.4e-05 24.8 1.7 1.8 1 0 0 1 1 1 1 DHHA1 domain Spore_YpjB PF09577.10 CDJ43010.1 - 0.021 14.6 3.0 0.021 14.6 3.0 2.5 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) DUF4781 PF16013.5 CDJ43010.1 - 0.61 8.8 4.3 1.5 7.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) G6PD_N PF00479.22 CDJ43010.1 - 7.5 7.1 9.9 0.5 11.0 0.8 2.4 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase, NAD binding domain RT_RNaseH PF17917.1 CDJ43011.1 - 6.5e-25 87.4 0.0 9.6e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ43011.1 - 2.1e-24 85.5 0.0 3.1e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase YsaB PF13983.6 CDJ43011.1 - 0.059 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 YsaB-like lipoprotein Scramblase PF03803.15 CDJ43011.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Scramblase SMC_N PF02463.19 CDJ43012.1 - 8.9e-15 54.7 0.1 1.1e-14 54.4 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ43012.1 - 2.8e-08 34.0 0.1 3.1e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CDJ43012.1 - 3.3e-06 27.3 0.1 6.1e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 CDJ43012.1 - 2.6e-05 24.1 0.0 2.6e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 CDJ43012.1 - 0.0024 18.4 0.8 0.0052 17.3 0.2 1.9 2 1 0 2 2 2 1 ABC transporter SMC_hinge PF06470.13 CDJ43013.1 - 6.3e-11 42.6 0.0 6.3e-11 42.6 0.0 3.8 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.19 CDJ43013.1 - 5e-09 35.9 0.0 5e-09 35.9 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDJ43013.1 - 2.2e-07 31.6 0.0 2.2e-07 31.6 0.0 5.3 3 2 2 5 5 5 1 AAA domain AAA_21 PF13304.6 CDJ43013.1 - 0.097 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Actin PF00022.19 CDJ43014.1 - 6.8e-76 255.5 0.0 1.4e-68 231.4 0.0 2.3 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 CDJ43014.1 - 0.0037 16.1 0.0 0.099 11.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein SUIM_assoc PF16619.5 CDJ43014.1 - 0.0083 16.2 6.4 7.2 6.8 5.5 3.2 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Prenyltrans PF00432.21 CDJ43015.1 - 4.4e-35 119.1 21.7 5.6e-12 45.2 1.0 5.5 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Spt20 PF12090.8 CDJ43016.1 - 3 7.4 14.4 3.1 7.4 14.4 1.0 1 0 0 1 1 1 0 Spt20 family Pam16 PF03656.13 CDJ43017.1 - 4.5e-11 42.9 0.0 5.5e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Pam16 N6_N4_Mtase PF01555.18 CDJ43018.1 - 0.045 13.5 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 DNA methylase UPF0020 PF01170.18 CDJ43018.1 - 0.16 11.6 0.0 0.6 9.8 0.0 1.9 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Trigger_C PF05698.14 CDJ43019.1 - 2.6e-14 53.5 9.4 6.5e-14 52.3 9.4 1.7 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus Trigger_N PF05697.13 CDJ43019.1 - 0.00081 19.7 0.2 0.037 14.3 0.0 2.8 3 0 0 3 3 3 1 Bacterial trigger factor protein (TF) BolA PF01722.18 CDJ43020.1 - 0.076 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 BolA-like protein Ribosomal_L24e PF01246.20 CDJ43021.1 - 6.6e-24 83.9 0.9 6.6e-24 83.9 0.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 CDJ43021.1 - 0.074 12.6 0.2 0.085 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) APO_RNA-bind PF05634.11 CDJ43021.1 - 1.5 8.2 8.4 1.3 8.4 7.6 1.3 1 1 0 1 1 1 0 APO RNA-binding zf-CCHC PF00098.23 CDJ43022.1 - 3.6e-06 26.8 2.3 3.6e-06 26.8 2.3 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ43022.1 - 0.0043 16.9 1.2 0.0043 16.9 1.2 2.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ43022.1 - 0.0079 16.1 7.6 0.01 15.8 0.5 2.5 1 1 1 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 CDJ43022.1 - 0.017 15.4 0.0 0.099 12.9 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_2 PF13696.6 CDJ43022.1 - 0.019 14.8 1.9 0.019 14.8 1.9 2.3 2 0 0 2 2 2 0 Zinc knuckle zinc-ribbons_6 PF07191.12 CDJ43022.1 - 0.033 14.2 1.1 0.067 13.2 1.1 1.4 1 0 0 1 1 1 0 zinc-ribbons DUF3425 PF11905.8 CDJ43022.1 - 0.12 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) DnaJ_CXXCXGXG PF00684.19 CDJ43022.1 - 0.59 10.5 10.2 1.8 9.0 10.2 1.7 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC_4 PF14392.6 CDJ43022.1 - 0.6 9.9 5.7 0.36 10.6 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF4588 PF15251.6 CDJ43022.1 - 1.5 8.5 4.8 3.1 7.5 0.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4588) Asp_protease_2 PF13650.6 CDJ43023.1 - 5.3e-07 30.2 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ43023.1 - 9.3e-06 26.1 0.0 1.9e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ43023.1 - 5.6e-05 22.9 0.0 9.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF3552 PF12072.8 CDJ43023.1 - 0.071 12.5 2.2 0.1 12.0 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) VPS11_C PF12451.8 CDJ43024.1 - 1.3e-05 25.3 0.1 3.9e-05 23.8 0.1 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 CDJ43024.1 - 0.0034 17.3 0.4 0.011 15.6 0.1 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 CDJ43024.1 - 0.0056 16.7 4.4 0.019 15.0 4.4 1.9 1 0 0 1 1 1 1 Zinc-finger PHD PF00628.29 CDJ43024.1 - 0.0066 16.3 0.5 0.025 14.4 0.5 2.1 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.6 CDJ43024.1 - 0.016 15.1 1.2 0.016 15.1 1.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ43024.1 - 0.027 14.3 2.2 0.12 12.2 2.3 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ43024.1 - 0.28 11.2 3.6 0.96 9.5 3.6 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 CDJ43024.1 - 0.85 10.0 6.9 7.2 7.0 7.0 2.6 1 1 1 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 CDJ43024.1 - 1.5 8.9 4.4 0.52 10.4 1.0 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 CDJ43024.1 - 2.8 8.3 10.8 0.73 10.2 1.2 3.5 3 0 0 3 3 3 0 RING-H2 zinc finger domain IMCp PF12314.8 CDJ43025.1 - 6.4e-26 90.5 50.3 9.2e-25 86.8 20.3 3.5 1 1 2 3 3 3 3 Inner membrane complex protein ubiquitin PF00240.23 CDJ43026.1 - 1.2e-13 50.5 0.2 1.3e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_4 PF18036.1 CDJ43026.1 - 0.0012 18.8 2.5 0.04 14.0 0.3 3.1 2 2 0 2 2 2 1 Ubiquitin-like domain UN_NPL4 PF11543.8 CDJ43026.1 - 0.08 13.4 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 ANAPC15 PF15243.6 CDJ43027.1 - 0.24 11.8 7.3 0.3 11.5 7.3 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Mog1 PF04603.12 CDJ43028.1 - 5e-30 104.7 0.0 6.4e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Notch PF00066.17 CDJ43029.1 - 1.1e-41 140.9 103.1 4.4e-08 33.4 10.4 6.5 6 0 0 6 6 6 6 LNR domain DUF4949 PF16307.5 CDJ43029.1 - 0.0095 16.0 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4949) Raf1_HTH PF18579.1 CDJ43031.1 - 0.082 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain E3_binding PF02817.17 CDJ43032.1 - 0.076 13.4 0.1 0.28 11.6 0.0 2.0 2 0 0 2 2 2 0 e3 binding domain Fasciclin PF02469.22 CDJ43033.1 - 9.2e-07 29.1 0.0 2.4e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain Myb_DNA-binding PF00249.31 CDJ43034.1 - 1.8e-10 40.9 0.2 3.7e-10 39.8 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ43034.1 - 1.7e-06 28.2 0.3 1.7e-06 28.2 0.3 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain EF-hand_1 PF00036.32 CDJ43037.1 - 9.2e-21 71.8 0.6 7.9e-07 28.2 0.2 3.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CDJ43037.1 - 6.1e-20 71.4 0.5 1.1e-12 48.2 0.2 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ43037.1 - 1.5e-18 65.1 0.2 1.9e-06 27.4 0.0 3.5 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CDJ43037.1 - 1.9e-12 46.8 0.5 8.6e-06 25.5 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CDJ43037.1 - 4.3e-12 45.0 0.6 1e-05 24.8 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_11 PF08976.11 CDJ43037.1 - 5.1e-05 24.1 0.0 6.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 CDJ43037.1 - 0.00024 21.0 0.1 0.91 9.5 0.0 2.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CDJ43037.1 - 0.00075 19.8 0.1 0.011 16.1 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CDJ43037.1 - 0.0021 18.3 0.0 0.006 16.9 0.0 1.7 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CDJ43037.1 - 0.0034 17.3 0.0 0.15 12.0 0.0 2.3 1 1 1 2 2 2 1 Caleosin related protein Dockerin_1 PF00404.18 CDJ43037.1 - 0.041 14.1 0.1 0.36 11.1 0.0 2.4 2 1 0 2 2 2 0 Dockerin type I domain DUF5580 PF17743.1 CDJ43037.1 - 0.11 11.0 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) MHCassoc_trimer PF08831.10 CDJ43037.1 - 0.16 12.0 0.3 9.4 6.3 0.1 2.4 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain DUF1547 PF07577.11 CDJ43037.1 - 0.16 12.4 0.0 0.66 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) Myb_DNA-binding PF00249.31 CDJ43038.1 - 0.012 15.8 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain PikAIV_N PF18605.1 CDJ43039.1 - 0.00033 20.2 16.6 0.027 14.1 4.9 4.1 3 0 0 3 3 3 2 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Leu_zip PF15294.6 CDJ43039.1 - 0.095 12.2 26.6 0.028 13.9 13.3 3.5 2 1 0 3 3 3 0 Leucine zipper YabA PF06156.13 CDJ43039.1 - 6.5 7.4 20.2 1.1 10.0 2.5 3.9 2 1 2 4 4 4 0 Initiation control protein YabA CS PF04969.16 CDJ43040.1 - 7.6e-15 55.7 0.0 1.5e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 CDJ43040.1 - 6.9e-12 45.2 0.2 1.4e-11 44.2 0.2 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. FGF-BP1 PF06473.12 CDJ43040.1 - 0.4 10.5 0.0 0.4 10.5 0.0 3.0 2 2 1 3 3 3 0 FGF binding protein 1 (FGF-BP1) SLC12 PF03522.15 CDJ43040.1 - 3.5 6.6 12.8 0.71 8.8 7.7 1.9 2 0 0 2 2 2 0 Solute carrier family 12 DUF3987 PF13148.6 CDJ43040.1 - 3.6 6.5 9.2 9.5 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DDE_Tnp_ISL3 PF01610.17 CDJ43041.1 - 3.1 7.5 7.5 0.33 10.7 1.6 2.3 2 0 0 2 2 2 0 Transposase Peptidase_S24 PF00717.23 CDJ43042.1 - 1.1e-09 38.1 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like RNase_H2_suC PF08615.11 CDJ43044.1 - 4.3e-13 49.7 0.0 9.7e-13 48.5 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PsbQ PF05757.11 CDJ43044.1 - 0.024 14.4 0.5 0.024 14.4 0.5 1.8 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) UPF0016 PF01169.19 CDJ43045.1 - 4.7e-34 116.6 18.2 4e-19 68.7 3.8 3.4 3 1 0 3 3 3 2 Uncharacterized protein family UPF0016 B12-binding PF02310.19 CDJ43045.1 - 0.12 12.4 0.1 0.35 10.9 0.0 1.7 2 0 0 2 2 2 0 B12 binding domain DUF4131 PF13567.6 CDJ43045.1 - 6.4 6.4 8.7 5.1 6.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Ion_trans PF00520.31 CDJ43047.1 - 0.00067 19.0 9.6 0.00092 18.5 9.6 1.1 1 0 0 1 1 1 1 Ion transport protein TNFR_16_TM PF18422.1 CDJ43047.1 - 0.25 11.3 1.6 0.57 10.2 1.6 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF5090 PF17009.5 CDJ43047.1 - 0.38 10.7 6.2 0.53 10.2 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) PCI PF01399.27 CDJ43049.1 - 5.1e-09 36.6 0.0 1.8e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 PCI domain GNAT_acetyltr_2 PF13718.6 CDJ43050.1 - 0.0027 17.1 0.2 0.0045 16.4 0.2 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase 2 SpoIIP PF07454.11 CDJ43050.1 - 0.0087 15.6 0.8 0.013 15.0 0.8 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Suf PF05843.14 CDJ43050.1 - 0.022 14.8 3.6 0.039 13.9 3.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.17 CDJ43050.1 - 0.029 14.5 0.5 0.029 14.5 0.5 1.4 2 0 0 2 2 2 0 DDHD domain Presenilin PF01080.17 CDJ43050.1 - 0.052 12.3 3.3 0.072 11.8 3.3 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ43050.1 - 0.37 9.7 8.4 0.52 9.2 8.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 CDJ43050.1 - 2.5 8.3 6.0 4.4 7.5 6.0 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.13 CDJ43050.1 - 2.5 8.7 13.9 4.5 7.9 13.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 CDJ43050.1 - 3.2 7.4 4.4 5 6.8 4.4 1.2 1 0 0 1 1 1 0 Connexin FAM176 PF14851.6 CDJ43050.1 - 3.3 7.4 6.1 5.4 6.7 6.1 1.3 1 0 0 1 1 1 0 FAM176 family TFIIA PF03153.13 CDJ43050.1 - 5.3 6.9 24.0 7.6 6.4 24.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNAP PF14938.6 CDJ43051.1 - 0.099 12.1 13.2 0.14 11.6 12.9 1.4 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP DUF3253 PF11625.8 CDJ43051.1 - 9.7 6.5 6.3 22 5.4 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3253) Rep_fac-A_C PF08646.10 CDJ43052.1 - 2.2e-25 89.1 0.1 6.1e-20 71.4 0.1 3.1 3 0 0 3 3 3 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CDJ43052.1 - 3e-23 81.6 0.0 2.3e-21 75.5 0.1 3.0 3 0 0 3 3 3 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 CDJ43052.1 - 9.4e-13 48.0 0.1 5.9e-10 39.0 0.0 3.2 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF4503 PF14951.6 CDJ43052.1 - 3.8e-05 22.3 0.8 3.8e-05 22.3 0.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4503) CDC24_OB3 PF17244.2 CDJ43052.1 - 0.00023 20.9 0.2 0.0024 17.6 0.6 2.2 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 POT1 PF02765.17 CDJ43052.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 Zn_Tnp_IS1595 PF12760.7 CDJ43052.1 - 0.18 11.8 1.6 0.41 10.7 1.6 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain ThiD2 PF17792.1 CDJ43053.1 - 1.8 9.1 8.5 1.5 9.3 0.5 4.0 3 0 0 3 3 3 0 ThiD2 family AMMECR1 PF01871.17 CDJ43055.1 - 1.4e-37 128.9 0.5 4.8e-30 104.4 0.0 3.0 3 0 0 3 3 3 2 AMMECR1 CTD_bind PF04818.13 CDJ43056.1 - 0.01 16.6 0.0 0.12 13.2 0.0 2.8 2 1 0 2 2 2 0 RNA polymerase II-binding domain. SR-25 PF10500.9 CDJ43056.1 - 0.74 9.4 22.7 1.6 8.3 22.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ43057.1 - 0.0036 17.6 0.9 0.0036 17.6 0.9 8.6 4 3 4 8 8 8 2 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ43057.1 - 0.013 15.5 2.3 0.013 15.5 2.3 12.4 9 3 2 11 11 11 0 Unstructured region C-term to UIM in Ataxin3 DUF898 PF05987.13 CDJ43057.1 - 9.4 5.2 9.6 37 3.2 3.9 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF898) Peptidase_C54 PF03416.19 CDJ43058.1 - 6e-12 45.6 0.6 1.4e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase family C54 SR-25 PF10500.9 CDJ43058.1 - 0.015 14.9 0.7 0.015 14.9 0.7 11.2 9 2 2 11 11 11 0 Nuclear RNA-splicing-associated protein RNA_pol_Rpc34 PF05158.12 CDJ43060.1 - 4.5e-35 121.6 0.4 1.2e-24 87.4 0.0 3.0 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit UBA_3 PF09288.10 CDJ43060.1 - 0.067 13.0 0.1 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Skp1_POZ PF03931.15 CDJ43061.1 - 1.6e-21 76.2 0.1 3e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 CDJ43061.1 - 3.1e-18 65.6 0.0 5.5e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain RskA PF10099.9 CDJ43061.1 - 0.034 14.4 1.3 0.048 14.0 1.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Acyltransferase PF01553.21 CDJ43063.1 - 4e-05 23.3 0.0 0.0001 22.0 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase DUF4939 PF16297.5 CDJ43063.1 - 0.064 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) DnaJ PF00226.31 CDJ43064.1 - 0.0071 16.4 0.2 0.02 15.0 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain LuxT_C PF18285.1 CDJ43064.1 - 0.083 13.4 0.2 1.9 9.1 0.1 2.9 2 0 0 2 2 2 0 Tetracycline repressor LuxT C-terminal domain AAA PF00004.29 CDJ43065.1 - 1.7e-08 35.0 1.3 9.8e-05 22.8 0.0 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PIN_8 PF18476.1 CDJ43065.1 - 1.4 8.8 0.0 1.4 8.8 0.0 3.1 3 0 0 3 3 3 0 PIN like domain V_ATPase_I PF01496.19 CDJ43065.1 - 7.6 4.3 7.0 0.28 9.1 0.8 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family zf-HC5HC2H_2 PF13832.6 CDJ43066.1 - 6.1e-11 42.5 18.3 8.6e-07 29.1 0.0 3.2 3 0 0 3 3 3 2 PHD-zinc-finger like domain PHD_2 PF13831.6 CDJ43066.1 - 9.2e-10 37.9 1.9 9.2e-10 37.9 1.9 4.0 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 CDJ43066.1 - 2.4e-09 36.9 5.1 2.4e-09 36.9 5.1 3.4 4 0 0 4 4 4 1 PHD-finger zf-HC5HC2H PF13771.6 CDJ43066.1 - 7.3e-05 22.9 19.8 0.0015 18.7 9.2 4.2 4 0 0 4 4 4 1 PHD-like zinc-binding domain C1_1 PF00130.22 CDJ43066.1 - 0.0012 18.7 0.1 0.0012 18.7 0.1 3.7 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 CDJ43066.1 - 0.0038 17.1 2.9 0.013 15.4 2.9 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PGA_cap PF09587.10 CDJ43067.1 - 0.58 9.6 4.5 0.16 11.4 1.0 1.8 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap IMPa_helical PF18642.1 CDJ43068.1 - 0.027 14.9 0.4 6.2 7.3 0.1 2.5 2 0 0 2 2 2 0 Immunomodulating metalloprotease helical domain SRP68 PF16969.5 CDJ43069.1 - 8.7e-46 157.1 15.4 6e-43 147.7 10.6 2.3 2 0 0 2 2 2 2 RNA-binding signal recognition particle 68 Cytochrom_C1 PF02167.15 CDJ43070.1 - 1.3e-87 293.1 0.0 2e-87 292.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CDJ43070.1 - 0.0037 17.6 0.0 0.0074 16.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CDJ43070.1 - 0.039 15.1 0.0 0.083 14.0 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c Sulfate_transp PF00916.20 CDJ43071.1 - 2.6e-22 79.1 17.9 2.9e-21 75.7 17.9 2.0 1 1 0 1 1 1 1 Sulfate permease family ATP-synt_I PF03899.15 CDJ43071.1 - 0.3 11.5 0.0 0.3 11.5 0.0 3.4 3 0 0 3 3 3 0 ATP synthase I chain Ufd2P_core PF10408.9 CDJ43072.1 - 5e-129 431.7 0.0 6e-129 431.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CDJ43072.1 - 4.5e-27 94.0 0.9 8.9e-27 93.1 0.9 1.5 1 0 0 1 1 1 1 U-box domain zf-Tim10_DDP PF02953.15 CDJ43073.1 - 1.4e-14 53.5 7.8 4.2e-14 52.0 7.8 1.7 1 1 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 CDJ43073.1 - 0.0086 15.8 4.4 0.015 15.0 4.4 1.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF1039 PF06287.11 CDJ43073.1 - 0.089 13.2 0.3 0.13 12.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) PIH1 PF08190.12 CDJ43074.1 - 8.4e-17 61.1 0.0 1.5e-12 47.3 0.0 2.4 1 1 1 2 2 2 2 PIH1 N-terminal domain HDPD PF02924.14 CDJ43074.1 - 0.39 10.8 15.8 0.081 13.0 2.1 2.6 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D SPOR PF05036.13 CDJ43074.1 - 0.87 10.0 4.3 11 6.5 0.1 3.6 2 1 1 3 3 3 0 Sporulation related domain L27_2 PF09045.10 CDJ43075.1 - 0.063 13.3 0.1 0.063 13.3 0.1 2.6 2 1 1 3 3 3 0 L27_2 ATP-synt_S1 PF05827.12 CDJ43075.1 - 0.17 11.7 1.0 0.58 10.0 0.1 2.0 2 0 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF3235 PF11574.8 CDJ43076.1 - 0.25 12.2 1.3 0.78 10.6 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Apo-CIII PF05778.12 CDJ43078.1 - 0.0082 15.8 0.1 0.052 13.2 0.0 2.5 2 0 0 2 2 2 1 Apolipoprotein CIII (Apo-CIII) DNA_pol_B PF00136.21 CDJ43081.1 - 9e-102 341.1 0.0 1.2e-101 340.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_alpha_N PF12254.8 CDJ43081.1 - 7.9e-15 54.7 3.1 2.1e-14 53.3 3.1 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_exo1 PF03104.19 CDJ43081.1 - 1.3e-13 50.9 0.0 1.1e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain BPS1 PF05633.11 CDJ43081.1 - 0.0011 18.1 2.1 0.32 9.9 3.5 2.3 2 0 0 2 2 2 2 Protein BYPASS1-related zf-DNA_Pol PF08996.10 CDJ43081.1 - 0.028 14.2 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Zn-ribbon_8 PF09723.10 CDJ43081.1 - 0.22 11.7 6.5 0.34 11.1 0.8 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Plasmodium_Vir PF05795.11 CDJ43081.1 - 8 5.8 6.8 1.4 8.2 1.5 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein AP2 PF00847.20 CDJ43082.1 - 4.9e-13 49.1 5.3 1.2e-12 47.9 5.3 1.7 1 0 0 1 1 1 1 AP2 domain Collagen PF01391.18 CDJ43082.1 - 0.2 11.4 3.1 0.53 10.1 3.1 1.7 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Med15 PF09606.10 CDJ43082.1 - 0.8 8.3 111.2 1.7 7.2 111.2 1.5 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Mob_Pre PF01076.19 CDJ43083.1 - 0.21 11.4 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Plasmid recombination enzyme 2OG-FeII_Oxy_2 PF13532.6 CDJ43084.1 - 0.005 17.0 0.3 0.038 14.2 0.3 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Acyl-CoA_dh_N PF02771.16 CDJ43086.1 - 4.1e-20 72.5 0.0 1.1e-19 71.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 CDJ43086.1 - 1.4e-13 51.3 5.7 2.1e-13 50.7 5.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ43086.1 - 5.2e-12 45.8 0.0 9.9e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CDJ43086.1 - 1e-07 32.3 10.4 1.7e-07 31.6 10.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_M50 PF02163.22 CDJ43087.1 - 0.00034 19.9 1.2 0.00034 19.9 1.2 2.2 1 1 1 2 2 2 1 Peptidase family M50 Autophagy_C PF10381.9 CDJ43087.1 - 0.19 11.3 2.2 0.54 9.8 2.2 1.7 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal eRF1_1 PF03463.15 CDJ43088.1 - 1.3e-31 109.3 0.0 3.2e-31 108.0 0.0 1.7 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.15 CDJ43088.1 - 5e-16 59.2 0.1 2e-15 57.2 0.1 2.1 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_2 PF03464.15 CDJ43088.1 - 1.5e-15 57.6 0.0 2.7e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 SUIM_assoc PF16619.5 CDJ43088.1 - 0.026 14.6 2.6 0.026 14.6 2.6 2.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ43088.1 - 0.26 10.9 6.4 0.22 11.1 4.2 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ43089.1 - 3.4 7.6 25.4 0.27 11.2 18.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4179 PF13786.6 CDJ43090.1 - 1.9 9.0 6.1 4.2 7.9 1.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) GDI PF00996.18 CDJ43091.1 - 8.8e-206 683.5 0.0 1e-205 683.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 CDJ43091.1 - 0.032 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ43091.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SBDS PF01172.18 CDJ43092.1 - 7e-29 99.7 0.0 1.4e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 CDJ43092.1 - 6.8e-19 68.0 1.0 1.6e-18 66.8 0.0 2.2 2 0 0 2 2 2 1 SBDS protein C-terminal domain Retrotrans_gag PF03732.17 CDJ43093.1 - 0.026 14.8 0.0 0.25 11.6 0.1 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein Retrotrans_gag PF03732.17 CDJ43094.1 - 0.0015 18.8 0.1 0.0075 16.5 0.2 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein WD40 PF00400.32 CDJ43095.1 - 4.7e-08 33.6 5.5 0.0062 17.4 0.0 5.1 5 1 0 5 5 5 3 WD domain, G-beta repeat Itfg2 PF15907.5 CDJ43095.1 - 0.13 11.2 0.0 0.69 8.9 0.0 1.9 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 Symplekin_C PF12295.8 CDJ43096.1 - 6.3e-39 134.0 0.2 7.8e-39 133.7 0.2 1.1 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal CCDC53 PF10152.9 CDJ43100.1 - 2.1 8.8 6.3 0.49 10.8 1.3 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Ribosomal_S6e PF01092.19 CDJ43101.1 - 2.3e-52 176.2 0.0 4.5e-52 175.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Chromo PF00385.24 CDJ43102.1 - 5.7e-13 48.5 0.0 1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CENP-R PF06729.12 CDJ43104.1 - 2.4 8.1 4.7 15 5.5 0.1 2.4 2 0 0 2 2 2 0 Kinetochore component, CENP-R TraE PF05309.11 CDJ43105.1 - 0.17 11.3 0.0 0.68 9.3 0.0 1.9 2 0 0 2 2 2 0 TraE protein DUF4834 PF16118.5 CDJ43108.1 - 0.21 12.6 0.1 0.21 12.6 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CDJ43108.1 - 0.39 8.6 1.1 0.64 7.9 1.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RCR PF12273.8 CDJ43109.1 - 0.25 12.0 0.1 0.25 12.0 0.1 3.3 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red SNF2_N PF00176.23 CDJ43110.1 - 9.9e-69 231.7 0.5 4.8e-68 229.4 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ43110.1 - 2.5e-18 66.4 0.1 1.2e-17 64.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CDJ43110.1 - 6.4e-13 48.5 0.7 2e-12 46.9 0.7 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 CDJ43110.1 - 3.5e-07 30.4 0.0 1.5e-06 28.3 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ43110.1 - 8.8e-06 25.6 0.9 3.4e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase UBA_e1_thiolCys PF10585.9 CDJ43110.1 - 0.16 11.8 0.1 0.16 11.8 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin-activating enzyme active site Sad1_UNC PF07738.13 CDJ43112.1 - 1.1e-12 48.1 0.0 1.1e-12 48.1 0.0 1.9 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Rft-1 PF04506.13 CDJ43113.1 - 1.5e-14 53.7 1.7 4.7e-08 32.2 0.6 2.1 2 0 0 2 2 2 2 Rft protein DUF2635 PF10948.8 CDJ43113.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) CLTH PF10607.9 CDJ43117.1 - 1.2e-20 73.9 0.0 1.7e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CDJ43117.1 - 2e-05 24.3 0.1 3.7e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 LisH NRIP1_repr_3 PF15689.5 CDJ43118.1 - 0.12 12.7 0.1 0.13 12.6 0.1 1.1 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 3 BTB PF00651.31 CDJ43119.1 - 3.1e-14 53.1 0.2 7.3e-14 51.9 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain Dus PF01207.17 CDJ43121.1 - 2.1e-46 158.4 0.0 1.1e-38 133.1 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) DUF3800 PF12686.7 CDJ43122.1 - 0.072 13.7 0.3 0.23 12.1 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Met_10 PF02475.16 CDJ43123.1 - 8.9e-47 159.4 0.0 1.2e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 CDJ43123.1 - 0.00063 19.0 0.1 0.00092 18.5 0.1 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_25 PF13649.6 CDJ43123.1 - 0.011 16.4 0.1 0.027 15.2 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 CDJ43123.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MethyltransfD12 PF02086.15 CDJ43123.1 - 0.05 13.3 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase SAM_MT PF04445.13 CDJ43123.1 - 0.055 12.9 0.1 0.094 12.1 0.1 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase gpW PF02831.15 CDJ43124.1 - 0.069 13.1 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 gpW Orai-1 PF07856.12 CDJ43124.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Mediator of CRAC channel activity Col_cuticle_N PF01484.17 CDJ43124.1 - 0.87 9.7 2.8 1.7 8.8 2.8 1.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain P4Ha_N PF08336.11 CDJ43124.1 - 1.6 8.7 6.2 1.6 8.7 1.2 2.8 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Ribosomal_S30 PF04758.14 CDJ43129.1 - 1.5e-25 89.2 6.8 1.7e-25 89.0 6.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 Fib_alpha PF08702.10 CDJ43131.1 - 0.04 14.1 0.5 0.04 14.1 0.5 2.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family NTP_transferase PF00483.23 CDJ43131.1 - 0.12 12.0 0.6 0.31 10.6 0.6 1.7 1 0 0 1 1 1 0 Nucleotidyl transferase Gp-FAR-1 PF05823.12 CDJ43131.1 - 0.14 12.5 2.5 0.29 11.5 2.5 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) YscO-like PF16789.5 CDJ43131.1 - 0.18 11.8 5.4 0.43 10.6 5.4 1.6 1 0 0 1 1 1 0 YscO-like protein CorA PF01544.18 CDJ43131.1 - 0.26 10.5 3.9 0.51 9.6 3.1 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein PIN_8 PF18476.1 CDJ43131.1 - 0.27 11.1 9.0 0.12 12.3 1.1 2.5 3 0 0 3 3 3 0 PIN like domain Prefoldin PF02996.17 CDJ43131.1 - 0.37 10.7 7.0 0.69 9.8 5.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit MIT PF04212.18 CDJ43131.1 - 0.38 10.9 6.6 4 7.6 0.7 2.7 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain Spc7 PF08317.11 CDJ43131.1 - 0.53 9.1 7.9 1.1 8.1 7.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein BST2 PF16716.5 CDJ43131.1 - 0.69 10.5 8.9 0.24 12.0 3.0 2.9 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 GrpE PF01025.19 CDJ43131.1 - 0.94 9.1 10.1 0.45 10.2 6.8 2.1 1 1 1 2 2 2 0 GrpE DUF4559 PF15112.6 CDJ43131.1 - 3.6 7.2 6.7 6.6 6.3 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) CLZ PF16526.5 CDJ43131.1 - 7.1 7.1 9.9 29 5.1 0.2 3.2 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FUSC PF04632.12 CDJ43131.1 - 7.1 5.0 9.8 17 3.7 9.8 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family ThiF PF00899.21 CDJ43132.1 - 2.4e-56 190.8 0.0 1.7e-31 109.4 0.0 4.8 4 1 0 4 4 4 4 ThiF family Shikimate_DH PF01488.20 CDJ43132.1 - 5.8e-05 23.2 0.0 0.3 11.2 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CDJ43132.1 - 0.0002 20.8 0.0 0.083 12.3 0.0 2.7 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UBA_e1_thiolCys PF10585.9 CDJ43132.1 - 0.00031 20.7 0.3 0.85 9.5 0.0 3.3 4 0 0 4 4 4 2 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CDJ43132.1 - 0.0017 19.0 0.0 0.006 17.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin fold domain Pyr_redox PF00070.27 CDJ43132.1 - 0.0048 17.4 0.9 2.2 8.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDJ43132.1 - 0.0064 15.8 0.0 4.4 6.4 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CDJ43132.1 - 0.01 16.3 0.1 0.65 10.5 0.0 3.1 2 0 0 2 2 2 1 Putative NAD(P)-binding HEPN_RiboL-PSP PF18735.1 CDJ43137.1 - 0.0093 15.9 1.2 3.8 7.4 0.4 2.4 2 0 0 2 2 2 2 RiboL-PSP-HEPN SPARC_Ca_bdg PF10591.9 CDJ43137.1 - 0.16 12.3 0.2 0.16 12.3 0.2 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Abi_C PF14355.6 CDJ43137.1 - 0.27 11.4 1.9 3.7 7.7 0.2 3.0 3 0 0 3 3 3 0 Abortive infection C-terminus Patched PF02460.18 CDJ43137.1 - 0.52 8.3 4.5 0.75 7.8 4.5 1.2 1 0 0 1 1 1 0 Patched family FAM184 PF15665.5 CDJ43137.1 - 2.7 7.7 30.3 0.34 10.6 21.7 2.6 1 1 0 2 2 2 0 Family with sequence similarity 184, A and B DUF1664 PF07889.12 CDJ43137.1 - 3.1 7.9 16.4 0.65 10.0 2.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Cytochrom_B562 PF07361.11 CDJ43137.1 - 6.6 7.4 19.5 0.47 11.1 2.4 3.9 4 0 0 4 4 4 0 Cytochrome b562 CCDC24 PF15669.5 CDJ43139.1 - 7.5 6.4 0.0 7.5 6.4 0.0 5.1 4 1 1 5 5 5 0 Coiled-coil domain-containing protein 24 family CDC45 PF02724.14 CDJ43140.1 - 0.036 12.4 13.4 0.008 14.5 9.0 1.9 2 0 0 2 2 2 0 CDC45-like protein DUF4179 PF13786.6 CDJ43140.1 - 0.19 12.3 0.5 1.2 9.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF1664 PF07889.12 CDJ43141.1 - 0.3 11.1 0.8 0.71 9.9 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LXG PF04740.12 CDJ43141.1 - 3.7 7.2 9.4 0.64 9.7 5.0 1.9 1 1 0 1 1 1 0 LXG domain of WXG superfamily Hormone_1 PF00103.20 CDJ43141.1 - 5.3 6.7 5.5 1.8 8.2 2.7 1.6 1 1 1 2 2 2 0 Somatotropin hormone family Baculo_PEP_C PF04513.12 CDJ43141.1 - 6.3 6.8 13.7 16 5.5 12.9 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ank_2 PF12796.7 CDJ43142.1 - 6.1e-12 46.0 0.9 4.8e-06 27.1 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ43142.1 - 2.5e-10 39.7 0.1 0.26 11.9 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 CDJ43142.1 - 6.3e-10 39.4 0.1 8.1e-07 29.5 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ43142.1 - 2.3e-08 34.1 0.4 3.2e-07 30.5 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CDJ43142.1 - 2.1e-06 27.9 0.8 3.4 8.3 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat SOG2 PF10428.9 CDJ43142.1 - 6.8 5.8 36.0 0.15 11.2 8.3 2.7 3 0 0 3 3 3 0 RAM signalling pathway protein DUF4611 PF15387.6 CDJ43143.1 - 0.0054 16.9 1.4 0.0068 16.6 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) ERM PF00769.19 CDJ43143.1 - 0.044 13.6 17.3 0.19 11.5 17.2 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family EMP24_GP25L PF01105.24 CDJ43143.1 - 0.057 13.3 1.8 0.048 13.6 1.2 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Atg14 PF10186.9 CDJ43143.1 - 0.066 12.3 10.0 0.074 12.1 10.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Trans_reg_C PF00486.28 CDJ43143.1 - 0.091 12.9 3.1 0.13 12.4 0.1 2.4 2 1 1 3 3 3 0 Transcriptional regulatory protein, C terminal Aminopep PF10023.9 CDJ43143.1 - 0.092 12.1 6.0 0.097 12.0 6.0 1.1 1 0 0 1 1 1 0 Putative aminopeptidase CENP-H PF05837.12 CDJ43143.1 - 0.4 11.1 11.7 0.42 11.0 11.0 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Csm1_N PF18504.1 CDJ43143.1 - 0.69 10.3 12.7 0.14 12.5 3.9 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain V_ATPase_I PF01496.19 CDJ43143.1 - 2.8 5.8 5.2 3.2 5.6 5.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 CDJ43143.1 - 4.2 8.1 7.9 5.8 7.6 7.8 1.4 1 1 0 1 1 1 0 Initiation control protein YabA FUSC PF04632.12 CDJ43143.1 - 4.5 5.7 6.1 5 5.5 6.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family FapA PF03961.13 CDJ43143.1 - 7.8 5.0 8.1 9.1 4.8 8.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Mitofilin PF09731.9 CDJ43144.1 - 0.053 12.4 13.2 0.06 12.2 13.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Spt20 PF12090.8 CDJ43144.1 - 0.13 11.9 7.5 0.14 11.8 7.5 1.3 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 CDJ43144.1 - 1.5 7.4 8.5 1.7 7.3 8.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 CDJ43144.1 - 8.5 6.3 18.3 11 5.9 18.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ACCA PF03255.14 CDJ43149.1 - 0.083 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit OATP PF03137.20 CDJ43150.1 - 1.7e-09 36.6 0.1 4.7e-09 35.1 0.0 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 CDJ43150.1 - 3.5e-08 32.8 39.1 1.6e-06 27.3 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ43150.1 - 1.2e-06 27.6 5.6 1.7e-06 27.2 5.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TFIIA PF03153.13 CDJ43150.1 - 1.7 8.6 9.8 2.3 8.1 9.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit S4 PF01479.25 CDJ43151.1 - 2.2e-12 46.5 0.4 2.2e-12 46.5 0.4 2.1 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 CDJ43151.1 - 4.5e-06 27.5 1.5 6.3e-06 27.0 1.1 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DOT1 PF08123.13 CDJ43152.1 - 4.8e-05 23.0 0.0 8.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 EGF_2 PF07974.13 CDJ43153.1 - 6.1e-22 77.7 185.6 0.0001 22.6 6.7 11.1 9 1 1 10 10 10 8 EGF-like domain AMA-1 PF02430.15 CDJ43153.1 - 1.4e-17 63.9 2.6 1.3e-13 50.8 0.7 3.0 3 0 0 3 3 3 2 Apical membrane antigen 1 hEGF PF12661.7 CDJ43153.1 - 2.2e-08 34.4 113.5 0.022 15.4 5.3 11.3 10 0 0 10 10 10 8 Human growth factor-like EGF EGF PF00008.27 CDJ43153.1 - 0.00098 19.4 27.6 0.0011 19.2 5.7 10.7 10 0 0 10 10 10 5 EGF-like domain CLAG PF03805.13 CDJ43154.1 - 3.2e-08 31.7 0.0 1.5e-07 29.5 0.0 1.8 1 1 0 2 2 2 1 Cytoadherence-linked asexual protein DUF569 PF04601.13 CDJ43157.1 - 0.087 12.5 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF569) MCU PF04678.13 CDJ43157.1 - 0.25 11.4 1.4 0.52 10.4 1.4 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter YitT_membrane PF02588.15 CDJ43157.1 - 3.1 7.1 7.3 2.2 7.6 1.7 2.4 2 0 0 2 2 2 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 F-box-like PF12937.7 CDJ43158.1 - 8.9e-05 22.3 0.7 8.9e-05 22.3 0.7 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 CDJ43158.1 - 0.25 11.3 3.0 1.3 9.0 3.0 2.3 1 0 0 1 1 1 0 F-box domain FapA PF03961.13 CDJ43158.1 - 0.52 8.8 3.0 1 7.9 3.0 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A WXG100 PF06013.12 CDJ43158.1 - 7.7 6.8 15.0 0.83 9.9 1.9 3.7 3 0 0 3 3 3 0 Proteins of 100 residues with WXG 5_nucleotid_C PF02872.18 CDJ43159.1 - 9.9e-37 126.6 0.0 2.3e-36 125.4 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CDJ43159.1 - 2.8e-06 28.0 0.5 1.7e-05 25.4 0.5 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ank_2 PF12796.7 CDJ43161.1 - 1.7e-39 134.3 0.3 2.9e-13 50.2 0.1 5.7 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ43161.1 - 2.4e-30 104.5 0.2 1.4e-05 25.5 0.0 8.0 5 2 4 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ43161.1 - 9.8e-29 99.0 4.5 0.00013 22.2 0.0 7.3 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ43161.1 - 1.6e-27 92.5 0.6 0.032 14.8 0.0 10.2 10 0 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 CDJ43161.1 - 2.6e-19 68.7 0.8 0.08 13.4 0.0 10.0 11 0 0 11 11 11 5 Ankyrin repeat AAA_23 PF13476.6 CDJ43161.1 - 1.9 8.9 13.0 0.71 10.3 4.0 2.6 2 0 0 2 2 2 0 AAA domain SWI-SNF_Ssr4 PF08549.10 CDJ43162.1 - 0.046 12.4 3.7 0.05 12.2 3.7 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SPATA3 PF15662.5 CDJ43162.1 - 0.37 11.4 13.7 0.43 11.2 13.7 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Fcf1 PF04900.12 CDJ43163.1 - 1e-33 115.6 1.9 1e-33 115.6 1.9 1.7 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 CDJ43163.1 - 2e-14 53.9 0.1 2e-14 53.9 0.1 1.5 2 0 0 2 2 2 1 PIN like domain PIN PF01850.21 CDJ43163.1 - 0.3 11.6 1.5 19 5.7 0.0 2.5 2 1 1 3 3 3 0 PIN domain YqzE PF14038.6 CDJ43163.1 - 1.4 9.0 6.3 2.8 8.0 6.3 1.5 1 0 0 1 1 1 0 YqzE-like protein OST3_OST6 PF04756.13 CDJ43164.1 - 5.8e-05 22.6 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF641 PF04859.12 CDJ43165.1 - 2.8e-31 108.5 156.0 0.083 13.2 1.6 20.4 16 1 1 17 17 17 15 Plant protein of unknown function (DUF641) KASH_CCD PF14662.6 CDJ43165.1 - 2.6e-19 69.8 243.1 0.09 12.6 4.9 17.6 16 1 1 17 17 16 14 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 CDJ43165.1 - 2e-14 53.2 196.9 0.12 11.2 1.7 17.1 15 2 1 17 17 16 14 Spc7 kinetochore protein Med30 PF11315.8 CDJ43165.1 - 6.2e-13 49.2 125.6 1.9 8.7 0.5 17.6 16 1 0 17 17 17 14 Mediator complex subunit 30 Tweety PF04906.13 CDJ43165.1 - 2.7e-12 46.1 93.0 1.6 7.3 0.2 17.2 16 1 2 18 18 18 14 Tweety DUF3450 PF11932.8 CDJ43165.1 - 2.7e-11 43.3 158.9 0.6 9.4 0.6 18.2 16 1 2 18 18 18 14 Protein of unknown function (DUF3450) DUF1654 PF07867.11 CDJ43165.1 - 3e-11 42.9 43.1 32 4.4 0.1 14.9 15 0 0 15 15 15 0 Protein of unknown function (DUF1654) Cytochrom_B562 PF07361.11 CDJ43165.1 - 6.1e-10 39.7 105.9 8.5 7.1 0.4 17.3 16 1 0 17 17 17 0 Cytochrome b562 Lebercilin PF15619.6 CDJ43165.1 - 2.7e-09 37.0 233.9 0.11 12.2 6.1 18.2 16 2 1 17 17 16 14 Ciliary protein causing Leber congenital amaurosis disease ING PF12998.7 CDJ43165.1 - 6.7e-09 36.3 115.4 7.1 7.3 0.3 18.6 16 1 2 19 19 19 13 Inhibitor of growth proteins N-terminal histone-binding Vps53_N PF04100.12 CDJ43165.1 - 1.5e-06 27.4 103.9 3.3 6.6 0.3 16.7 16 1 1 17 17 17 14 Vps53-like, N-terminal Y_phosphatase3 PF13350.6 CDJ43165.1 - 1.8e-05 24.9 39.7 77 3.1 0.2 14.7 15 0 0 15 15 15 0 Tyrosine phosphatase family Uso1_p115_C PF04871.13 CDJ43165.1 - 0.00013 22.3 196.6 1.8 9.0 2.4 17.9 16 1 2 18 18 18 14 Uso1 / p115 like vesicle tethering protein, C terminal region SKA2 PF16740.5 CDJ43165.1 - 0.0013 18.5 125.6 6.7 6.5 0.5 18.7 17 1 1 19 19 19 14 Spindle and kinetochore-associated protein 2 KxDL PF10241.9 CDJ43165.1 - 0.038 14.3 140.6 3.1 8.1 3.9 19.3 16 1 2 19 19 19 0 Uncharacterized conserved protein TMPIT PF07851.13 CDJ43165.1 - 0.42 9.8 129.4 4.7 6.4 0.5 17.1 16 1 1 17 17 17 0 TMPIT-like protein Fib_alpha PF08702.10 CDJ43165.1 - 0.7 10.1 115.6 23 5.1 0.3 17.6 16 1 1 17 17 17 0 Fibrinogen alpha/beta chain family Spc24 PF08286.11 CDJ43165.1 - 0.79 10.0 181.0 5.2 7.4 2.6 18.6 16 1 2 18 18 18 0 Spc24 subunit of Ndc80 COG2 PF06148.11 CDJ43165.1 - 0.92 9.6 139.7 8.3 6.5 1.0 17.6 16 1 2 18 18 18 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4735 PF15882.5 CDJ43165.1 - 2.1 7.7 107.2 12 5.2 0.7 15.8 15 1 0 15 15 15 0 Domain of unknown function (DUF4735) NYD-SP28 PF14772.6 CDJ43165.1 - 5.4 7.1 199.3 6.9 6.8 4.2 18.2 16 1 1 17 17 17 0 Sperm tail FtsX_ECD PF18075.1 CDJ43165.1 - 7.5 7.3 116.6 22 5.7 0.7 16.6 16 1 1 17 17 16 0 FtsX extracellular domain DUF4578 PF15147.6 CDJ43166.1 - 0.05 14.5 2.7 1.2 10.0 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) CARD PF00619.21 CDJ43167.1 - 0.07 13.2 0.2 1.7 8.7 0.1 2.8 2 1 1 3 3 3 0 Caspase recruitment domain DUF4227 PF14004.6 CDJ43167.1 - 0.16 11.9 0.6 0.57 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) JAB PF01398.21 CDJ43168.1 - 6.4e-12 45.5 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CDJ43168.1 - 3.7e-09 37.0 0.0 6.7e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF2336 PF10098.9 CDJ43168.1 - 0.026 14.0 2.0 0.048 13.1 2.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) HTH_3 PF01381.22 CDJ43168.1 - 0.18 11.9 0.0 0.44 10.7 0.0 1.7 1 1 1 2 2 2 0 Helix-turn-helix Thioredoxin PF00085.20 CDJ43169.1 - 7.3e-28 96.6 0.0 1.1e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CDJ43169.1 - 5.3e-06 26.8 0.2 6e-05 23.5 0.2 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 CDJ43169.1 - 4e-05 23.6 0.0 5.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 CDJ43169.1 - 0.0049 17.2 0.0 0.035 14.4 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.6 CDJ43169.1 - 0.0066 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CDJ43169.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 CDJ43169.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_7 PF13899.6 CDJ43169.1 - 0.016 15.3 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 CDJ43169.1 - 0.018 15.0 0.0 0.068 13.1 0.0 1.8 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 CDJ43169.1 - 0.047 13.5 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DUF4602 PF15375.6 CDJ43170.1 - 0.17 12.2 0.2 0.17 12.2 0.2 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4602) Lsr2 PF11774.8 CDJ43170.1 - 1.2 9.3 12.0 1.9 8.7 4.1 3.0 2 1 1 3 3 3 0 Lsr2 TIP_N PF12457.8 CDJ43170.1 - 1.5 9.3 12.3 0.35 11.3 0.2 3.1 3 0 0 3 3 3 0 Tuftelin interacting protein N terminal GTP_EFTU PF00009.27 CDJ43173.1 - 5.1e-35 120.8 0.0 8.9e-35 120.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CDJ43173.1 - 6e-15 55.0 0.0 1.3e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CDJ43173.1 - 6.1e-05 23.0 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 CDJ43173.1 - 0.0089 15.8 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV YIF1 PF03878.15 CDJ43174.1 - 8.4e-37 127.0 1.8 1.3e-34 119.8 0.3 2.0 2 0 0 2 2 2 2 YIF1 DUF1180 PF06679.12 CDJ43174.1 - 3.3 8.1 5.2 12 6.3 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) PCI PF01399.27 CDJ43175.1 - 2.1e-14 53.9 0.1 3.4e-12 46.8 0.0 2.4 2 0 0 2 2 2 2 PCI domain LCCL PF03815.19 CDJ43176.1 - 7.1e-21 74.1 0.1 1.9e-20 72.8 0.1 1.7 1 0 0 1 1 1 1 LCCL domain COLFI PF01410.18 CDJ43176.1 - 0.0035 16.7 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Rxt3 PF08642.10 CDJ43176.1 - 0.033 15.0 0.0 0.12 13.2 0.0 1.9 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 EcpB_C PF18649.1 CDJ43176.1 - 0.098 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 EcpB C-terminal domain Methyltransf_25 PF13649.6 CDJ43178.1 - 7.7e-22 77.8 0.0 3e-21 75.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ43178.1 - 4.5e-21 75.3 0.0 1.4e-20 73.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ43178.1 - 7.1e-18 65.0 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ43178.1 - 5.3e-16 58.8 0.0 8.5e-16 58.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CDJ43178.1 - 5.9e-14 52.0 0.0 9.2e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CDJ43178.1 - 4.2e-13 49.9 0.1 2.5e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ43178.1 - 8e-11 41.7 0.1 2.3e-08 33.6 0.0 2.2 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family MTS PF05175.14 CDJ43178.1 - 2.8e-05 23.7 0.0 4.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CDJ43178.1 - 8.1e-05 22.0 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_PK PF05891.12 CDJ43178.1 - 0.0002 20.9 0.0 0.00069 19.2 0.0 1.7 1 1 1 2 2 2 1 AdoMet dependent proline di-methyltransferase TPMT PF05724.11 CDJ43178.1 - 0.00078 19.2 0.0 0.005 16.5 0.0 2.0 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 CDJ43178.1 - 0.0036 17.1 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 CDJ43178.1 - 0.004 16.7 0.0 0.28 10.7 0.0 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain NodS PF05401.11 CDJ43178.1 - 0.0047 16.6 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.19 CDJ43178.1 - 0.0091 16.1 0.0 0.056 13.5 0.0 2.1 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 CDJ43178.1 - 0.019 14.4 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Reo_sigmaC PF04582.12 CDJ43178.1 - 0.039 14.2 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein C-terminal domain DOT1 PF08123.13 CDJ43178.1 - 0.046 13.2 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.20 CDJ43178.1 - 0.065 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase YscO-like PF16789.5 CDJ43178.1 - 0.084 12.9 1.1 0.15 12.1 1.1 1.4 1 0 0 1 1 1 0 YscO-like protein PrmA PF06325.13 CDJ43178.1 - 0.094 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 CDJ43178.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Str_synth PF03088.16 CDJ43179.1 - 8.4e-08 32.2 0.0 3.7e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 CDJ43179.1 - 0.0011 18.6 0.0 0.0038 16.8 0.0 1.8 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region RRM_1 PF00076.22 CDJ43180.1 - 3.8e-14 52.3 0.0 5.5e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_1 PF00515.28 CDJ43181.1 - 0.039 13.8 1.5 0.75 9.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ43181.1 - 0.058 13.4 0.5 0.35 11.0 0.5 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ43181.1 - 1.7 8.9 12.2 0.12 12.5 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Ras PF00071.22 CDJ43183.1 - 9e-60 201.0 0.0 1.1e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ43183.1 - 7.7e-34 116.5 0.0 1.2e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ43183.1 - 7.5e-13 48.3 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ43183.1 - 1.5e-06 27.8 0.0 1.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ43183.1 - 0.00019 21.5 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ43183.1 - 0.026 14.1 0.0 0.11 12.1 0.0 1.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ43183.1 - 0.028 14.4 0.0 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 CDJ43183.1 - 0.031 13.8 0.0 0.065 12.8 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 CDJ43183.1 - 0.072 13.5 0.1 0.1 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain MORN PF02493.20 CDJ43184.1 - 1.7e-49 162.8 52.8 2.4e-06 27.1 3.0 10.2 10 0 0 10 10 10 10 MORN repeat DUF3048_C PF17479.2 CDJ43184.1 - 3.5 8.0 9.0 21 5.5 0.4 3.8 1 1 2 4 4 4 0 Protein of unknown function (DUF3048) C-terminal domain Pkinase PF00069.25 CDJ43185.1 - 4.3e-35 121.4 0.0 1.7e-26 93.2 0.0 4.2 4 1 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ43185.1 - 1.7e-34 119.3 0.1 3e-14 52.9 0.0 5.0 3 2 0 3 3 3 3 Protein tyrosine kinase AAA PF00004.29 CDJ43186.1 - 5.3e-17 62.5 0.0 8.4e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CDJ43186.1 - 6.1e-13 48.9 0.1 6.2e-11 42.3 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CDJ43186.1 - 5.1e-11 42.8 0.0 1.4e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 CDJ43186.1 - 2.1e-06 28.0 0.1 3e-05 24.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ43186.1 - 4.3e-06 27.2 0.1 0.00033 21.1 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 CDJ43186.1 - 6e-06 26.1 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDJ43186.1 - 2e-05 24.4 0.0 8.2e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 CDJ43186.1 - 2.2e-05 24.4 0.1 6.2e-05 22.9 0.0 1.5 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 CDJ43186.1 - 2.4e-05 24.4 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 CDJ43186.1 - 0.00012 22.3 0.0 0.00032 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain ResIII PF04851.15 CDJ43186.1 - 0.001 19.1 0.0 0.012 15.6 0.0 2.0 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit Rad17 PF03215.15 CDJ43186.1 - 0.0034 17.3 0.0 0.0069 16.3 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 CDJ43186.1 - 0.0034 17.4 0.1 0.016 15.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CDJ43186.1 - 0.0045 17.3 0.1 0.017 15.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CDJ43186.1 - 0.0067 15.7 0.0 0.016 14.5 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CDJ43186.1 - 0.013 15.1 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 CDJ43186.1 - 0.017 14.9 0.1 0.23 11.2 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_24 PF13479.6 CDJ43186.1 - 0.019 14.7 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CDJ43186.1 - 0.043 13.2 0.1 0.26 10.6 0.1 2.0 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDJ43186.1 - 0.068 13.0 0.1 0.79 9.6 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CDJ43186.1 - 0.094 12.1 0.0 5.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 CDJ43186.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 CDJ43186.1 - 0.13 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CDJ43186.1 - 0.16 11.4 0.0 5.1 6.5 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Mer2 PF09074.10 CDJ43188.1 - 0.0013 18.6 9.7 0.0018 18.2 9.7 1.3 1 0 0 1 1 1 1 Mer2 Syntaxin-6_N PF09177.11 CDJ43188.1 - 0.0013 19.2 7.3 0.0013 19.2 7.3 2.1 1 1 0 2 2 2 1 Syntaxin 6, N-terminal DUF1664 PF07889.12 CDJ43188.1 - 0.0023 17.9 12.0 0.0066 16.5 5.9 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) Lipoprotein_6 PF01441.19 CDJ43188.1 - 0.0074 16.3 4.4 0.012 15.7 3.9 1.6 1 1 0 1 1 1 1 Lipoprotein HMMR_N PF15905.5 CDJ43188.1 - 0.0083 15.6 19.7 0.012 15.1 19.7 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 CDJ43188.1 - 0.013 15.1 21.1 0.061 12.9 10.2 2.2 1 1 1 2 2 2 0 Intermediate filament protein Laminin_II PF06009.12 CDJ43188.1 - 0.016 15.3 6.5 0.016 15.3 6.5 2.3 1 1 1 2 2 2 0 Laminin Domain II PspA_IM30 PF04012.12 CDJ43188.1 - 0.023 14.3 18.5 0.26 10.9 9.4 2.3 1 1 1 2 2 2 0 PspA/IM30 family Gp58 PF07902.11 CDJ43188.1 - 0.036 12.4 6.4 0.041 12.2 6.4 1.1 1 0 0 1 1 1 0 gp58-like protein ApoLp-III PF07464.11 CDJ43188.1 - 0.075 13.1 12.7 0.68 10.0 11.9 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 CDJ43188.1 - 0.085 13.5 9.3 0.3 11.7 2.4 2.8 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) CHDCT2 PF08074.11 CDJ43188.1 - 0.11 12.7 9.9 0.73 10.0 9.9 2.0 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain EST1 PF10374.9 CDJ43188.1 - 0.18 12.5 7.3 0.24 12.0 7.0 1.5 1 1 0 1 1 1 0 Telomerase activating protein Est1 Cob_adeno_trans PF01923.18 CDJ43188.1 - 0.18 12.0 5.5 0.13 12.4 3.3 1.7 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF948 PF06103.11 CDJ43188.1 - 0.19 12.0 4.6 5.6 7.3 0.2 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NBD_C PF17042.5 CDJ43188.1 - 0.2 12.2 4.9 0.29 11.6 4.9 1.4 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain DUF4706 PF15797.5 CDJ43188.1 - 0.23 12.0 3.9 0.24 11.9 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4706) TMF_TATA_bd PF12325.8 CDJ43188.1 - 0.31 11.3 24.9 1.4 9.1 2.8 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding OmpH PF03938.14 CDJ43188.1 - 0.38 11.1 25.4 0.077 13.3 14.5 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 CDJ43188.1 - 0.8 9.2 13.7 0.98 8.9 13.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.7 CDJ43188.1 - 0.88 9.7 27.3 0.84 9.8 13.5 2.6 1 1 1 2 2 2 0 Tropomyosin like Spectrin PF00435.21 CDJ43188.1 - 1.3 9.6 17.1 4.5 7.8 8.8 2.5 1 1 1 2 2 2 0 Spectrin repeat Baculo_PEP_C PF04513.12 CDJ43188.1 - 1.9 8.5 9.7 8.8 6.4 4.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.13 CDJ43188.1 - 2.1 7.5 12.7 4.6 6.4 9.8 2.0 1 1 1 2 2 2 0 TMPIT-like protein ZYG-11_interact PF05884.12 CDJ43188.1 - 2.2 7.6 4.1 9.7 5.5 4.0 1.9 1 1 0 1 1 1 0 Interactor of ZYG-11 Atg14 PF10186.9 CDJ43188.1 - 3 6.9 14.4 4.4 6.3 14.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 CDJ43188.1 - 3.6 7.4 14.9 0.5 10.2 7.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 CDJ43188.1 - 3.9 6.7 14.9 7.3 5.9 14.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1481 PF07356.12 CDJ43188.1 - 4.2 7.1 10.0 0.49 10.1 2.5 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1481) Tweety PF04906.13 CDJ43188.1 - 4.4 5.9 6.6 8.6 4.9 2.5 2.0 1 1 1 2 2 2 0 Tweety Spc7 PF08317.11 CDJ43188.1 - 4.4 6.1 20.3 6 5.6 19.0 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein 7TMR-HDED PF07697.11 CDJ43188.1 - 4.6 7.3 20.3 12 5.9 20.3 1.6 1 1 0 1 1 1 0 7TM-HD extracellular YlqD PF11068.8 CDJ43188.1 - 6.4 7.2 21.4 0.5 10.7 4.4 2.6 1 1 1 2 2 2 0 YlqD protein SbcD_C PF12320.8 CDJ43188.1 - 7.5 6.9 14.0 8.4 6.8 1.1 2.5 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain V_ATPase_I PF01496.19 CDJ43188.1 - 9.6 4.0 10.3 13 3.5 8.8 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Cation_efflux PF01545.21 CDJ43189.1 - 2.1e-45 154.9 6.1 2.6e-45 154.6 6.1 1.1 1 0 0 1 1 1 1 Cation efflux family Virul_fac_BrkB PF03631.15 CDJ43190.1 - 0.12 12.0 0.1 0.66 9.5 0.1 2.0 2 0 0 2 2 2 0 Virulence factor BrkB DNA_pol_A_exo1 PF01612.20 CDJ43191.1 - 6.5e-35 120.4 0.0 1.3e-34 119.4 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 CDJ43191.1 - 5.6e-10 39.1 0.1 1.3e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 CDJ43191.1 - 0.019 15.7 0.7 0.61 10.8 0.4 3.3 2 1 0 2 2 2 0 PMC2NT (NUC016) domain RNase_T PF00929.24 CDJ43192.1 - 3e-28 99.5 0.0 3.4e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 CDJ43192.1 - 0.00066 19.7 0.0 0.00082 19.4 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like eIF2A PF08662.11 CDJ43193.1 - 2.7e-46 157.9 0.0 2.6e-43 148.2 0.0 3.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A GYF PF02213.16 CDJ43193.1 - 5.6e-16 57.9 0.1 1.4e-15 56.6 0.1 1.8 1 0 0 1 1 1 1 GYF domain ANAPC4_WD40 PF12894.7 CDJ43193.1 - 0.013 15.8 1.2 7.5 6.9 0.0 4.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain K_channel_TID PF07941.11 CDJ43197.1 - 0.41 11.1 8.3 0.91 10.0 8.3 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF4357 PF14267.6 CDJ43197.1 - 6.6 6.8 0.0 6.6 6.8 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4357) DUF3449 PF11931.8 CDJ43198.1 - 1.6e-75 252.9 1.3 3e-75 252.1 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 CDJ43198.1 - 1.8e-08 34.8 0.4 4.1e-08 33.6 0.4 1.6 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Vfa1 PF08432.10 CDJ43198.1 - 0.038 14.3 6.4 0.12 12.7 6.4 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Desulfoferrod_N PF06397.12 CDJ43198.1 - 0.11 12.1 0.2 0.18 11.5 0.2 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain RPN2_C PF18004.1 CDJ43198.1 - 3.8 7.4 9.7 1.4 8.8 6.6 1.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DLIC PF05783.11 CDJ43199.1 - 2.3e-14 53.1 0.0 2.5e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) Tctex-1 PF03645.13 CDJ43201.1 - 2.5e-16 59.8 0.0 2.9e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family SpoIIP PF07454.11 CDJ43202.1 - 0.2 11.1 10.9 0.087 12.3 2.4 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CGI-121 PF08617.10 CDJ43203.1 - 7.5e-11 42.4 0.1 7.5e-11 42.4 0.1 2.6 3 1 0 3 3 3 1 Kinase binding protein CGI-121 DUF755 PF05501.11 CDJ43203.1 - 0.00033 20.9 22.4 0.00033 20.9 22.4 4.1 4 0 0 4 4 3 1 Domain of unknown function (DUF755) Apt1 PF10351.9 CDJ43203.1 - 0.00071 18.6 2.6 0.00071 18.6 2.6 2.0 3 0 0 3 3 2 1 Golgi-body localisation protein domain TFIIA PF03153.13 CDJ43203.1 - 0.02 14.9 42.0 0.24 11.4 7.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ43203.1 - 0.024 14.2 44.5 0.033 13.8 27.6 2.2 2 0 0 2 2 2 0 Spt20 family EPL1 PF10513.9 CDJ43203.1 - 0.031 14.7 8.5 0.03 14.7 2.7 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Ndc1_Nup PF09531.10 CDJ43203.1 - 0.031 13.0 11.2 0.0058 15.4 5.1 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Velvet PF11754.8 CDJ43203.1 - 0.043 13.7 11.6 0.22 11.5 7.3 2.3 2 0 0 2 2 2 0 Velvet factor Tim54 PF11711.8 CDJ43203.1 - 0.25 10.1 3.3 0.27 10.0 0.8 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 NPR1_interact PF15699.5 CDJ43203.1 - 0.3 11.7 6.8 0.66 10.6 2.4 2.5 2 0 0 2 2 2 0 NPR1 interacting DUF3657 PF12394.8 CDJ43203.1 - 0.32 11.6 4.3 1.2 9.7 1.5 2.8 2 0 0 2 2 2 0 Protein FAM135 Mit_KHE1 PF10173.9 CDJ43203.1 - 0.33 11.0 2.9 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Activator_LAG-3 PF11498.8 CDJ43203.1 - 0.47 9.4 43.9 0.48 9.3 11.3 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Plasmodium_Vir PF05795.11 CDJ43203.1 - 0.87 8.9 5.4 1.5 8.2 5.4 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Miga PF10265.9 CDJ43203.1 - 1 8.2 11.6 0.2 10.6 7.6 1.8 2 0 0 2 2 2 0 Mitoguardin DUF2722 PF10846.8 CDJ43203.1 - 1.6 7.6 37.1 0.22 10.4 21.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ43203.1 - 1.7 7.3 14.8 0.2 10.4 8.8 2.1 2 0 0 2 2 2 0 Presenilin CCSAP PF15748.5 CDJ43203.1 - 1.8 8.7 17.5 1.7 8.7 13.0 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Neur_chan_memb PF02932.16 CDJ43203.1 - 2.6 8.0 7.5 2.9 7.9 4.9 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ43203.1 - 3 6.8 7.5 0.56 9.2 3.5 1.7 2 0 0 2 2 2 0 CLN3 protein CCDC117 PF15810.5 CDJ43203.1 - 3.1 8.1 13.7 0.84 9.9 8.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 117 EIF4E-T PF10477.9 CDJ43203.1 - 3.7 6.3 22.7 1.9 7.2 10.1 2.1 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF572 PF04502.13 CDJ43203.1 - 4.5 6.8 14.8 0.86 9.2 9.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) MPM1 PF17234.2 CDJ43203.1 - 5.8 7.1 18.5 0.67 10.2 10.6 2.3 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Slu7 PF11708.8 CDJ43203.1 - 6.8 6.3 16.2 3.1 7.5 6.6 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor DUF4770 PF15994.5 CDJ43203.1 - 7.3 6.8 15.2 2.2 8.5 7.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) GREB1 PF15782.5 CDJ43203.1 - 7.3 3.6 17.2 0.15 9.2 10.7 1.4 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer AAA_23 PF13476.6 CDJ43203.1 - 7.3 7.0 11.7 6.7 7.1 4.6 2.2 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 CDJ43203.1 - 8.9 5.0 7.8 18 4.0 7.8 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) zf-CCCH PF00642.24 CDJ43205.1 - 7.1e-11 41.7 23.6 0.00036 20.4 1.5 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ43205.1 - 0.001 19.1 29.0 0.03 14.4 7.1 3.9 3 1 0 3 3 3 3 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ43205.1 - 0.0022 17.8 20.6 0.17 11.7 3.1 3.6 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 CDJ43205.1 - 0.0025 18.5 5.1 0.0025 18.5 5.1 4.3 2 1 2 4 4 4 3 Torus domain IMUP PF15761.5 CDJ43205.1 - 0.016 15.9 5.3 0.016 15.9 5.3 4.4 4 1 0 4 4 4 0 Immortalisation up-regulated protein RskA PF10099.9 CDJ43205.1 - 0.02 15.2 41.8 2.6 8.3 5.8 4.4 2 1 1 3 3 3 0 Anti-sigma-K factor rskA zf-CCCH_3 PF15663.5 CDJ43205.1 - 0.022 15.0 5.6 0.022 15.0 5.6 3.1 2 1 1 3 3 3 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDJ43205.1 - 0.11 13.0 15.9 1 9.9 1.5 3.5 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger SR-25 PF10500.9 CDJ43205.1 - 0.57 9.7 33.8 0.12 12.0 9.2 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 CDJ43206.1 - 3.8e-38 131.4 0.0 7.2e-24 84.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ43206.1 - 8.4e-20 71.1 0.1 2.5e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ43206.1 - 2.9e-07 30.1 0.1 0.0077 15.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CDJ43206.1 - 0.0018 18.3 0.9 0.0018 18.3 0.9 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ43206.1 - 0.0064 15.3 1.2 0.012 14.5 0.0 1.7 1 1 1 2 2 2 1 Fungal protein kinase SR-25 PF10500.9 CDJ43206.1 - 0.15 11.6 7.0 0.26 10.9 7.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1772 PF08592.11 CDJ43206.1 - 0.28 11.5 13.9 0.48 10.7 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF5327 PF17261.2 CDJ43206.1 - 4.3 8.2 6.7 3.4 8.5 2.3 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5327) RskA PF10099.9 CDJ43206.1 - 9.9 6.4 38.8 0.69 10.2 8.9 2.5 2 1 1 3 3 3 0 Anti-sigma-K factor rskA PUA_3 PF17785.1 CDJ43207.1 - 2.8e-12 46.3 0.0 6e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain Aminotran_1_2 PF00155.21 CDJ43209.1 - 8.7e-40 137.0 0.0 1.5e-38 133.0 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CDJ43209.1 - 0.00021 20.7 0.0 0.00057 19.3 0.0 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CDJ43209.1 - 0.0029 16.9 0.1 0.029 13.7 0.0 2.1 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CDJ43209.1 - 0.0066 15.0 0.0 0.0096 14.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 CDJ43209.1 - 0.0096 14.7 0.0 0.026 13.3 0.0 1.6 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain ERGIC_N PF13850.6 CDJ43210.1 - 0.03 14.7 1.2 0.14 12.5 0.4 2.4 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) NGP1NT PF08153.12 CDJ43211.1 - 3.7e-34 117.7 0.0 9.5e-34 116.4 0.0 1.6 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CDJ43211.1 - 1.1e-15 57.7 0.0 8.9e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ43211.1 - 1.2e-06 28.5 0.0 2.8e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 CDJ43211.1 - 4.1e-06 26.4 0.0 0.0035 16.9 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDJ43211.1 - 0.00094 18.8 0.1 0.011 15.3 0.0 2.3 1 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.21 CDJ43211.1 - 0.0013 18.2 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 CDJ43211.1 - 0.14 12.2 0.1 8.4 6.4 0.0 2.9 2 1 1 3 3 3 0 Dynamin family Beta-Casp PF10996.8 CDJ43212.1 - 3e-22 79.0 0.0 6.2e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 CDJ43212.1 - 5.1e-16 58.4 0.0 1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 CDJ43212.1 - 3.3e-09 36.5 0.0 1.3e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ43212.1 - 1e-05 25.7 0.1 0.00019 21.5 0.0 2.8 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDJ43212.1 - 0.00092 18.8 0.1 0.19 11.2 0.0 3.2 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Cpn60_TCP1 PF00118.24 CDJ43214.1 - 3.5e-81 273.3 0.6 9.9e-81 271.8 0.6 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family GP3_package PF16677.5 CDJ43214.1 - 0.15 12.2 1.6 4.5 7.5 0.1 2.5 1 1 0 2 2 2 0 DNA-packaging protein gp3 DNA_primase_lrg PF04104.14 CDJ43214.1 - 0.57 9.5 1.9 4.8 6.5 0.2 2.2 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit GBP PF02263.19 CDJ43216.1 - 3.7e-18 65.7 0.0 1.8e-13 50.4 0.0 2.5 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 CDJ43216.1 - 2.1e-12 47.1 18.3 3.2e-12 46.5 18.3 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain LMBR1 PF04791.16 CDJ43216.1 - 8.1 5.2 8.8 14 4.4 8.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein MFS_1 PF07690.16 CDJ43217.1 - 3.3e-11 42.7 19.1 8.4e-11 41.4 19.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily ERGIC_N PF13850.6 CDJ43217.1 - 0.12 12.7 2.3 0.33 11.3 0.4 2.6 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2678 PF10856.8 CDJ43217.1 - 0.39 10.6 4.1 1.5 8.7 4.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) TRAPPC-Trs85 PF12739.7 CDJ43218.1 - 3.8e-78 263.3 5.7 6.4e-78 262.5 5.7 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF2722 PF10846.8 CDJ43218.1 - 0.00059 18.9 3.9 0.00059 18.9 3.9 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) SNAP PF14938.6 CDJ43218.1 - 0.021 14.3 0.5 0.066 12.6 0.0 1.9 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Velvet PF11754.8 CDJ43218.1 - 0.73 9.7 13.2 0.91 9.4 2.5 2.7 2 0 0 2 2 2 0 Velvet factor TFIIA PF03153.13 CDJ43218.1 - 6.5 6.6 65.0 1.4 8.9 25.3 3.4 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ43218.1 - 6.8 5.3 14.6 0.43 9.3 1.4 2.2 2 0 0 2 2 2 0 Presenilin DUF842 PF05811.13 CDJ43219.1 - 1.2e-28 99.4 10.6 1.4e-28 99.2 10.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) TBCC_N PF16752.5 CDJ43219.1 - 0.79 10.2 3.6 3.7 8.0 0.2 2.8 1 1 2 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Rubis-subs-bind PF09273.11 CDJ43220.1 - 0.0034 18.1 0.0 0.0083 16.8 0.0 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 CDJ43220.1 - 0.04 14.3 0.0 3.4 8.0 0.0 2.8 2 1 0 2 2 2 0 SET domain Asp PF00026.23 CDJ43222.1 - 9.4e-66 222.4 0.0 1.2e-65 222.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ43222.1 - 7.8e-06 26.2 0.3 7.8e-06 26.2 0.3 3.1 2 2 2 4 4 4 2 Xylanase inhibitor N-terminal M_domain PF12938.7 CDJ43222.1 - 0.11 12.2 13.1 2.7 7.7 0.1 2.2 2 0 0 2 2 2 0 M domain of GW182 RskA PF10099.9 CDJ43222.1 - 0.52 10.6 6.5 0.85 9.9 6.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Spore_YtfJ PF09579.10 CDJ43222.1 - 0.86 9.8 3.1 0.47 10.6 0.1 2.2 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) Phage_r1t_holin PF16945.5 CDJ43222.1 - 1 9.6 5.8 2.2 8.5 5.8 1.4 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin Spt20 PF12090.8 CDJ43222.1 - 9.5 5.8 6.9 16 5.0 6.9 1.3 1 0 0 1 1 1 0 Spt20 family LAP1C PF05609.12 CDJ43223.1 - 0.12 11.4 2.0 0.2 10.7 2.0 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PRELI PF04707.14 CDJ43224.1 - 1e-33 116.4 0.0 1.6e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 PRELI-like family Peptidase_C54 PF03416.19 CDJ43224.1 - 0.0086 15.5 0.0 0.016 14.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase family C54 Shisa PF13908.6 CDJ43224.1 - 0.0091 16.3 0.2 0.0091 16.3 0.2 2.9 4 1 0 4 4 4 1 Wnt and FGF inhibitory regulator SUIM_assoc PF16619.5 CDJ43224.1 - 3.4 7.8 10.6 0.065 13.3 1.1 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 MCM PF00493.23 CDJ43226.1 - 7.6e-91 303.2 0.0 1.1e-90 302.6 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CDJ43226.1 - 1.1e-20 73.8 0.9 5.6e-19 68.3 0.0 2.4 1 1 1 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDJ43226.1 - 1.4e-07 31.1 0.1 1.6e-05 24.4 0.1 2.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDJ43226.1 - 3.7e-07 30.2 0.0 1.4e-05 25.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDJ43226.1 - 1.5e-05 24.9 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ43226.1 - 0.1 12.4 0.1 0.48 10.2 0.1 2.0 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SUIM_assoc PF16619.5 CDJ43226.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MCM_N PF14551.6 CDJ43227.1 - 3.3e-07 30.9 0.0 6.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain XisI PF08869.11 CDJ43228.1 - 0.055 13.8 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 XisI protein DJ-1_PfpI PF01965.24 CDJ43229.1 - 5.5e-38 130.4 0.1 9.8e-38 129.5 0.1 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family MIF4G PF02854.19 CDJ43229.1 - 1e-27 97.2 10.1 3.3e-15 56.3 0.1 4.5 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 CDJ43229.1 - 2.1e-08 35.0 13.8 2.1e-08 35.0 13.8 5.3 7 0 0 7 7 7 1 Up-frameshift suppressor 2 DUF5327 PF17261.2 CDJ43229.1 - 0.22 12.3 0.0 0.22 12.3 0.0 7.6 7 1 1 8 8 8 0 Family of unknown function (DUF5327) DUF445 PF04286.12 CDJ43230.1 - 0.024 14.4 11.9 0.028 14.2 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) NopRA1 PF16201.5 CDJ43230.1 - 0.032 13.8 6.7 0.058 13.0 6.7 1.6 1 1 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 TFIIA PF03153.13 CDJ43230.1 - 0.22 11.5 42.4 0.26 11.3 42.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BPL_N PF09825.9 CDJ43230.1 - 0.36 9.9 8.6 0.39 9.7 8.6 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal PIN_12 PF16289.5 CDJ43230.1 - 0.5 10.8 2.6 0.67 10.4 2.6 1.2 1 0 0 1 1 1 0 PIN domain Herpes_UL92 PF03048.14 CDJ43230.1 - 0.85 9.4 7.4 1.2 8.9 7.4 1.2 1 0 0 1 1 1 0 UL92 family Hydant_A_N PF05378.13 CDJ43230.1 - 0.91 9.2 5.9 1.4 8.6 5.9 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region HI0933_like PF03486.14 CDJ43230.1 - 1.5 7.5 11.5 1.9 7.1 11.5 1.2 1 0 0 1 1 1 0 HI0933-like protein RIFIN PF02009.16 CDJ43230.1 - 1.6 8.6 16.5 1.8 8.4 16.5 1.0 1 0 0 1 1 1 0 Rifin Macoilin PF09726.9 CDJ43230.1 - 4.3 5.8 23.1 5 5.6 23.1 1.0 1 0 0 1 1 1 0 Macoilin family JUPITER PF17054.5 CDJ43231.1 - 2.8 7.3 14.9 3.1 7.2 14.9 1.2 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter SOBP PF15279.6 CDJ43231.1 - 8.1 7.0 13.0 10 6.6 13.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SR-25 PF10500.9 CDJ43231.1 - 9 5.8 34.8 6.3 6.3 31.4 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ43231.1 - 9.7 4.9 10.0 9.7 4.9 10.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spt20 PF12090.8 CDJ43233.1 - 9.8e-05 22.1 7.9 9.8e-05 22.1 7.9 1.4 2 0 0 2 2 2 1 Spt20 family Apt1 PF10351.9 CDJ43233.1 - 0.00054 18.9 2.5 0.00054 18.9 2.5 1.5 2 0 0 2 2 2 1 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 CDJ43233.1 - 0.014 14.8 0.9 0.017 14.5 0.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CDK2AP PF09806.9 CDJ43233.1 - 0.017 15.2 8.6 0.017 15.2 8.6 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF1645 PF07816.11 CDJ43233.1 - 0.32 11.6 24.4 0.052 14.1 12.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Lin-8 PF03353.15 CDJ43233.1 - 0.34 10.4 12.0 0.044 13.3 7.5 1.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF908 PF06012.12 CDJ43233.1 - 0.49 9.8 9.5 1.2 8.5 9.5 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MAP65_ASE1 PF03999.12 CDJ43233.1 - 0.8 8.3 9.9 1.4 7.6 9.9 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Presenilin PF01080.17 CDJ43233.1 - 0.83 8.3 8.0 1.2 7.8 8.0 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 CDJ43233.1 - 1.7 7.1 9.9 2.4 6.5 9.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Miga PF10265.9 CDJ43233.1 - 2.2 7.2 10.0 0.03 13.3 2.6 1.6 2 0 0 2 2 2 0 Mitoguardin Peroxin-3 PF04882.12 CDJ43233.1 - 3.6 6.5 13.7 7 5.5 13.7 1.4 1 0 0 1 1 1 0 Peroxin-3 PPP4R2 PF09184.11 CDJ43234.1 - 1.6 8.2 4.8 2.9 7.4 4.8 1.3 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 CDJ43234.1 - 3.9 6.1 4.8 8.1 5.1 4.8 1.4 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.22 CDJ43235.1 - 0.00078 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ43235.1 - 0.0035 17.4 0.0 0.017 15.2 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif AAA_23 PF13476.6 CDJ43235.1 - 0.0087 16.6 12.2 0.45 11.0 5.2 2.1 2 0 0 2 2 2 2 AAA domain CFIA_Pcf11 PF11526.8 CDJ43235.1 - 0.034 14.6 1.4 0.034 14.6 1.4 2.1 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 RskA PF10099.9 CDJ43235.1 - 0.035 14.4 12.7 0.15 12.3 2.1 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA FolB PF02152.18 CDJ43235.1 - 0.12 13.0 0.1 0.24 12.0 0.1 1.5 1 0 0 1 1 1 0 Dihydroneopterin aldolase DUF5327 PF17261.2 CDJ43235.1 - 0.22 12.3 14.7 0.61 10.9 5.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF3138 PF11336.8 CDJ43235.1 - 0.24 10.0 3.6 0.37 9.4 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) GBP_C PF02841.14 CDJ43235.1 - 0.86 8.9 21.8 0.24 10.8 2.0 2.1 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain eIF-3_zeta PF05091.12 CDJ43235.1 - 1.2 8.0 14.6 0.047 12.7 7.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BST2 PF16716.5 CDJ43235.1 - 2.4 8.8 24.8 0.22 12.1 3.6 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 NYN_YacP PF05991.11 CDJ43235.1 - 3.2 7.7 11.3 1.8 8.5 1.9 2.1 2 0 0 2 2 2 0 YacP-like NYN domain DUF4834 PF16118.5 CDJ43235.1 - 3.4 8.7 11.4 0.94 10.5 4.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2849 PF11011.8 CDJ43235.1 - 3.6 8.3 7.7 2.3 8.9 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) EPL1 PF10513.9 CDJ43235.1 - 5 7.5 10.6 1.7 9.0 2.9 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF179 PF02622.15 CDJ43236.1 - 7.2e-09 35.8 0.9 1.7e-05 24.8 0.0 3.0 3 0 0 3 3 3 2 Uncharacterized ACR, COG1678 DUF4564 PF15169.6 CDJ43236.1 - 1.8 8.3 5.3 0.25 11.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4564) Glycolytic PF00274.19 CDJ43237.1 - 9.3e-157 521.2 0.0 1.3e-156 520.7 0.0 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I RRM_1 PF00076.22 CDJ43238.1 - 1.1e-71 236.6 0.0 5.8e-20 70.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CDJ43238.1 - 4e-27 94.2 1.6 1.7e-26 92.2 1.2 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 CDJ43238.1 - 0.0065 16.4 0.0 5.2 7.2 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CDJ43238.1 - 0.017 15.2 0.0 4.4 7.5 0.0 3.5 3 1 0 3 3 3 0 RNA recognition motif OHA PF14418.6 CDJ43239.1 - 7.9e-21 73.7 0.0 2.2e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 OST-HTH Associated domain RAP PF08373.10 CDJ43240.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 RAP domain Mit_KHE1 PF10173.9 CDJ43240.1 - 0.16 12.0 3.4 0.13 12.3 1.0 2.1 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related NDUFA12 PF05071.16 CDJ43240.1 - 2 9.3 9.9 0.2 12.5 5.0 1.9 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 LRR_4 PF12799.7 CDJ43241.1 - 3.5e-15 55.9 21.0 1.8e-06 28.2 5.5 3.8 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ43241.1 - 1.9e-11 43.8 5.0 7e-07 28.9 0.2 2.5 2 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 CDJ43241.1 - 3.3e-09 36.3 11.8 2.4e-05 24.0 1.0 3.9 1 1 4 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 CDJ43241.1 - 0.0011 19.2 11.0 1.7 9.5 0.8 5.4 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 CDJ43241.1 - 0.0083 16.1 7.0 2.1 8.6 0.2 3.9 3 0 0 3 3 3 2 Leucine Rich repeat Adaptin_N PF01602.20 CDJ43243.1 - 2.9e-59 201.0 0.9 4.4e-54 183.9 1.0 2.2 2 0 0 2 2 2 2 Adaptin N terminal region AP4E_app_platf PF14807.6 CDJ43243.1 - 0.00028 21.2 0.0 0.00081 19.7 0.0 1.9 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform DUF5586 PF17824.1 CDJ43243.1 - 0.015 14.4 0.8 4 6.4 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5586) MRAP PF15183.6 CDJ43244.1 - 0.018 14.9 1.7 3.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family ODV-E18 PF10717.9 CDJ43244.1 - 0.18 11.7 0.4 0.18 11.7 0.4 2.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Neurokinin_B PF03823.14 CDJ43244.1 - 5.8 7.0 5.7 13 5.9 0.2 2.2 2 0 0 2 2 2 0 Neurokinin B DUF4051 PF13260.6 CDJ43244.1 - 9.5 6.0 12.2 12 5.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) ubiquitin PF00240.23 CDJ43245.1 - 2.4e-09 36.8 0.0 1.9e-07 30.7 0.0 3.0 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CDJ43245.1 - 4e-07 30.1 0.1 4e-07 30.1 0.1 3.5 3 1 1 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 CDJ43245.1 - 0.00019 22.0 0.8 0.00067 20.3 0.1 2.4 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD PF11976.8 CDJ43245.1 - 0.0007 19.4 0.0 0.0034 17.2 0.0 2.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDJ43245.1 - 0.0099 16.4 0.7 0.0099 16.4 0.7 5.2 3 1 0 3 3 3 1 DUF2407 ubiquitin-like domain zf-HIT PF04438.16 CDJ43246.1 - 2.8e-08 33.5 13.1 5.9e-08 32.4 13.1 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 CDJ43246.1 - 0.71 10.0 14.5 1.9 8.6 14.5 1.8 1 0 0 1 1 1 0 MYND finger DUF382 PF04037.13 CDJ43248.1 - 1.1e-50 171.1 0.6 1.1e-50 171.1 0.6 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 CDJ43248.1 - 4.9e-19 67.9 6.7 1.1e-18 66.8 6.7 1.6 1 0 0 1 1 1 1 PSP Voldacs PF03517.13 CDJ43248.1 - 0.0057 16.8 11.0 0.0057 16.8 11.0 2.1 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Na_trans_assoc PF06512.13 CDJ43248.1 - 0.38 11.0 20.4 0.23 11.7 16.1 2.4 2 0 0 2 2 2 0 Sodium ion transport-associated A1_Propeptide PF07966.12 CDJ43248.1 - 3 7.8 5.5 2.6 8.0 3.2 2.2 2 0 0 2 2 2 0 A1 Propeptide LMBR1 PF04791.16 CDJ43249.1 - 0.11 11.3 10.6 0.18 10.7 10.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 CDJ43249.1 - 0.25 10.2 21.9 0.41 9.5 21.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Tektin PF03148.14 CDJ43249.1 - 0.33 9.7 26.6 0.69 8.6 26.6 1.5 1 1 0 1 1 1 0 Tektin family UPF0242 PF06785.11 CDJ43249.1 - 0.33 11.0 19.0 0.59 10.2 19.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 CDJ43249.1 - 0.49 8.3 15.4 0.67 7.8 15.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAT1 PF09770.9 CDJ43249.1 - 0.58 8.4 21.6 0.72 8.0 21.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mucin15 PF15672.5 CDJ43249.1 - 0.66 9.4 2.8 0.95 8.9 2.8 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 DUF668 PF05003.12 CDJ43249.1 - 0.77 10.3 6.1 2.4 8.7 5.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF668) Golgin_A5 PF09787.9 CDJ43249.1 - 6.5 6.1 27.5 11 5.4 27.5 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 CDJ43249.1 - 6.7 6.2 30.4 0.024 14.2 21.1 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit SPX PF03105.19 CDJ43250.1 - 0.32 10.9 6.9 0.45 10.4 6.9 1.4 1 0 0 1 1 1 0 SPX domain SARAF PF06682.12 CDJ43250.1 - 4.2 6.9 6.9 5.9 6.4 6.9 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CAP PF00188.26 CDJ43251.1 - 0.00039 21.3 0.0 0.00056 20.8 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ43252.1 - 0.00042 21.2 0.0 0.0006 20.6 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ43253.1 - 0.0033 18.3 0.4 0.0047 17.8 0.4 1.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ43254.1 - 0.043 14.7 0.5 0.06 14.2 0.5 1.5 1 1 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ43255.1 - 0.051 14.4 0.6 0.071 13.9 0.6 1.5 1 1 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ43256.1 - 0.11 13.3 0.0 0.14 12.9 0.0 1.3 1 0 0 1 1 1 0 Cysteine-rich secretory protein family ELP6 PF09807.9 CDJ43258.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Elongation complex protein 6 CAP PF00188.26 CDJ43260.1 - 0.047 14.5 0.0 0.079 13.8 0.0 1.5 1 1 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ43261.1 - 0.064 14.1 0.0 0.085 13.7 0.0 1.3 1 0 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ43262.1 - 0.13 13.1 0.0 0.22 12.4 0.0 1.5 1 1 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ43265.1 - 0.0052 17.6 0.3 0.0077 17.1 0.3 1.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family RskA PF10099.9 CDJ43266.1 - 0.0007 19.9 3.7 0.0007 19.9 3.7 7.9 2 2 1 3 3 3 1 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ43266.1 - 0.0043 17.5 0.0 0.17 12.4 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4179) Clathrin PF00637.20 CDJ43267.1 - 1.5e-07 31.3 4.0 4.7e-06 26.5 0.2 3.1 2 2 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 CDJ43267.1 - 0.00021 21.7 0.0 0.00021 21.7 0.0 4.9 5 0 0 5 5 4 1 Vacuolar sorting protein 39 domain 2 DUF2722 PF10846.8 CDJ43267.1 - 0.0047 15.9 17.3 0.0047 15.9 17.3 4.2 3 1 1 4 4 2 1 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ43267.1 - 0.0054 16.8 35.3 0.045 13.7 13.3 3.1 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ43267.1 - 0.014 14.1 22.4 0.059 12.1 7.3 2.4 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 CDJ43267.1 - 0.02 15.0 14.1 0.5 10.4 2.2 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 CDJ43267.1 - 0.04 13.8 5.1 2.4 8.1 1.6 2.6 2 0 0 2 2 2 0 N-glycosylation protein Na_trans_assoc PF06512.13 CDJ43267.1 - 0.051 13.9 9.8 0.027 14.7 2.8 2.6 2 0 0 2 2 2 0 Sodium ion transport-associated Endostatin PF06482.11 CDJ43267.1 - 0.057 12.9 19.6 0.053 13.0 5.4 2.5 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin eIF-3_zeta PF05091.12 CDJ43267.1 - 0.18 10.8 27.3 0.46 9.4 6.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 CDJ43267.1 - 0.38 9.7 20.1 0.54 9.2 5.3 2.3 2 0 0 2 2 2 0 Solute carrier family 12 PBP1_TM PF14812.6 CDJ43267.1 - 0.61 10.5 6.0 0.5 10.8 1.6 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM60A PF15396.6 CDJ43267.1 - 0.62 10.0 16.1 1.8 8.5 4.8 2.6 2 0 0 2 2 2 0 Protein Family FAM60A DUF4746 PF15928.5 CDJ43267.1 - 0.74 9.2 15.8 0.14 11.6 4.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) SR-25 PF10500.9 CDJ43267.1 - 0.95 9.0 23.4 1.2 8.7 0.1 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.12 CDJ43267.1 - 2.4 7.9 28.1 1.4 8.7 13.2 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TFB6 PF17110.5 CDJ43267.1 - 2.4 7.9 13.3 2.9 7.6 4.6 2.8 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF5523 PF17661.1 CDJ43267.1 - 2.7 7.6 27.4 2 8.0 8.9 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Zip PF02535.22 CDJ43267.1 - 4.2 6.5 7.6 18 4.4 0.1 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4667 PF15700.5 CDJ43267.1 - 4.4 7.3 18.1 2.1 8.4 2.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) zf-C2H2_3rep PF18868.1 CDJ43267.1 - 4.5 8.0 11.9 1.2 9.9 2.2 3.0 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats CDK5_activator PF03261.15 CDJ43267.1 - 4.6 6.7 19.1 4.7 6.7 8.1 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein DUF4471 PF14740.6 CDJ43267.1 - 4.8 6.3 13.4 6.5 5.9 6.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) DUF3675 PF12428.8 CDJ43267.1 - 5.7 7.5 6.4 5.5 7.6 1.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Connexin PF00029.19 CDJ43267.1 - 6.9 6.4 18.7 0.94 9.2 5.6 2.6 3 0 0 3 3 2 0 Connexin Afi1 PF07792.12 CDJ43267.1 - 7 7.1 21.5 0.94 10.0 5.3 2.7 3 0 0 3 3 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RMP PF14996.6 CDJ43267.1 - 7.4 6.8 17.9 5.7 7.1 5.7 3.0 3 0 0 3 3 2 0 Retinal Maintenance Ferlin_C PF16165.5 CDJ43267.1 - 8.3 6.3 7.2 3.5 7.6 1.5 2.4 2 0 0 2 2 2 0 Ferlin C-terminus PAT1 PF09770.9 CDJ43267.1 - 9.5 4.3 54.7 0.26 9.5 14.1 2.6 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 EF-hand_1 PF00036.32 CDJ43268.1 - 1.7e-30 102.2 5.5 1.2e-08 33.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ43268.1 - 6.8e-28 96.9 1.4 4.3e-15 55.9 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ43268.1 - 1.3e-25 87.1 5.7 9.2e-09 34.6 0.0 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDJ43268.1 - 6.5e-23 80.3 8.5 2.3e-11 43.3 0.1 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CDJ43268.1 - 4.4e-14 51.2 11.5 2.7e-05 23.5 0.0 4.8 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.6 CDJ43268.1 - 1.1e-12 48.1 0.0 2.9e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDJ43268.1 - 1.9e-05 24.6 0.5 0.027 14.4 0.1 3.0 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 CDJ43268.1 - 0.0048 16.9 0.1 1.4 8.9 0.0 2.8 2 1 1 3 3 3 1 Tellurite resistance protein TerB EF-hand_14 PF17959.1 CDJ43268.1 - 0.005 17.2 0.1 2.2 8.7 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain Caleosin PF05042.13 CDJ43268.1 - 0.0082 16.1 0.0 4.8 7.1 0.0 2.8 2 1 1 3 3 3 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 CDJ43268.1 - 0.016 15.5 0.0 2.2 8.6 0.0 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Arc_PepC PF06819.11 CDJ43268.1 - 0.023 14.8 0.4 0.077 13.1 0.3 1.8 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain Smoothelin PF12510.8 CDJ43268.1 - 0.1 12.7 2.5 0.13 12.4 0.4 2.2 3 0 0 3 3 3 0 Smoothelin cytoskeleton protein EcoEI_R_C PF08463.10 CDJ43268.1 - 0.11 12.7 0.2 1.1 9.3 0.1 2.1 2 0 0 2 2 2 0 EcoEI R protein C-terminal Peptidase_M24 PF00557.24 CDJ43268.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.5 2 0 0 2 2 2 0 Metallopeptidase family M24 DUF3008 PF11450.8 CDJ43268.1 - 0.13 12.4 1.6 0.19 11.9 0.3 1.9 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) Cript PF10235.9 CDJ43269.1 - 1.7e-14 54.1 5.6 1.7e-14 54.1 5.6 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 CDJ43269.1 - 0.0096 15.9 5.5 0.24 11.5 5.5 2.3 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 CDJ43269.1 - 0.032 15.0 7.0 0.05 14.3 3.6 2.4 2 1 0 2 2 2 0 zinc-ribbon family zf-FCS PF06467.14 CDJ43269.1 - 0.75 9.8 0.1 0.75 9.8 0.1 2.9 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Sar8_2 PF03058.14 CDJ43269.1 - 1.5 9.4 11.3 0.97 10.0 7.6 2.1 1 1 1 2 2 2 0 Sar8.2 family DiS_P_DiS PF06750.13 CDJ43269.1 - 1.6 8.9 8.4 0.86 9.8 4.3 2.4 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Kelch_1 PF01344.25 CDJ43270.1 - 1.1e-48 162.6 4.5 5.8e-10 38.6 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CDJ43270.1 - 4.6e-39 131.0 11.0 1.6e-07 31.0 0.1 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ43270.1 - 2.1e-36 123.0 10.8 2.2e-06 27.7 0.0 6.4 2 2 4 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CDJ43270.1 - 1.3e-35 121.0 18.6 4.9e-06 26.7 0.0 8.8 9 0 0 9 9 9 6 Galactose oxidase, central domain Kelch_4 PF13418.6 CDJ43270.1 - 1.7e-31 107.9 11.8 1.6e-06 28.0 0.1 6.6 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ43270.1 - 1.8e-28 98.0 4.4 7.9e-06 25.7 0.0 6.8 7 0 0 7 7 7 6 Kelch motif BTB PF00651.31 CDJ43270.1 - 1.7e-14 54.0 0.0 1.3e-13 51.2 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain Presenilin PF01080.17 CDJ43270.1 - 3.2 6.4 38.9 0.0068 15.2 12.6 2.6 3 0 0 3 3 3 0 Presenilin V_ATPase_I PF01496.19 CDJ43272.1 - 7.7e-176 586.4 0.0 1.2e-174 582.4 0.0 2.1 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family Spore_III_AB PF09548.10 CDJ43272.1 - 0.0062 16.7 0.0 0.022 14.9 0.0 2.0 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) Apt1 PF10351.9 CDJ43272.1 - 1.1 8.0 5.2 2.1 7.1 5.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain ALMT PF11744.8 CDJ43272.1 - 2.1 7.1 6.3 3.5 6.3 6.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SOBP PF15279.6 CDJ43272.1 - 5 7.6 9.8 0.92 10.1 5.4 1.8 2 0 0 2 2 2 0 Sine oculis-binding protein Proteasome PF00227.26 CDJ43273.1 - 6.5e-45 153.0 0.0 8.4e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ43273.1 - 2.8e-11 42.9 0.0 6.9e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ORF6C PF10552.9 CDJ43274.1 - 0.036 14.1 4.1 0.063 13.4 4.1 1.4 1 0 0 1 1 1 0 ORF6C domain betaPIX_CC PF16523.5 CDJ43274.1 - 0.068 13.0 8.5 0.13 12.1 8.5 1.4 1 0 0 1 1 1 0 betaPIX coiled coil CysG_dimeriser PF10414.9 CDJ43274.1 - 0.072 12.8 0.5 0.16 11.7 0.5 1.7 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region CENP-H PF05837.12 CDJ43274.1 - 1.1 9.6 10.3 0.098 13.1 3.6 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FmdE PF02663.14 CDJ43274.1 - 2.6 8.1 6.6 2.1 8.4 5.5 1.4 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon APG6_N PF17675.1 CDJ43274.1 - 2.8 8.5 13.1 5 7.7 13.1 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region DASH_Spc19 PF08287.11 CDJ43274.1 - 3.1 7.7 15.9 1.4 8.8 8.4 2.0 2 0 0 2 2 2 0 Spc19 Ribosomal_L34 PF00468.17 CDJ43274.1 - 6.7 6.8 12.7 1.2 9.2 3.2 2.3 2 0 0 2 2 2 0 Ribosomal protein L34 DHC_N1 PF08385.12 CDJ43275.1 - 3.7e-26 91.9 0.2 2e-23 82.9 0.2 2.1 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 DHC_N1 PF08385.12 CDJ43276.1 - 3.5e-61 207.5 0.0 8.9e-57 193.0 0.0 2.1 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CDJ43277.1 - 5.1e-113 378.2 8.5 5.1e-113 378.2 8.5 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 CDJ43277.1 - 1.7e-99 332.9 0.7 6.9e-94 314.5 0.0 3.2 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 CDJ43277.1 - 9e-10 38.7 0.0 2e-06 27.9 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) T2SSE PF00437.20 CDJ43277.1 - 0.0059 15.7 0.1 0.016 14.3 0.1 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein Nab2 PF11517.8 CDJ43277.1 - 0.017 15.4 0.0 0.22 11.8 0.0 2.7 2 0 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) AAA_7 PF12775.7 CDJ43277.1 - 0.019 14.5 1.1 0.056 13.0 0.2 2.2 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_29 PF13555.6 CDJ43277.1 - 0.02 14.6 0.1 0.051 13.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ43277.1 - 0.025 14.7 0.2 0.28 11.3 0.0 2.8 3 0 0 3 3 3 0 50S ribosome-binding GTPase APS_kinase PF01583.20 CDJ43277.1 - 0.052 13.4 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.10 CDJ43277.1 - 0.057 12.9 0.1 0.27 10.6 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Roc PF08477.13 CDJ43277.1 - 0.071 13.3 2.5 0.31 11.2 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 CDJ43277.1 - 0.12 11.8 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF1611 PF07755.11 CDJ43277.1 - 0.13 11.6 0.1 0.27 10.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain AAA_16 PF13191.6 CDJ43277.1 - 0.15 12.4 0.0 2.8 8.3 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 CDJ43277.1 - 0.16 12.3 0.1 2.8 8.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_8 PF12780.7 CDJ43278.1 - 5e-87 291.5 0.0 1.1e-86 290.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CDJ43278.1 - 5.7e-51 172.6 0.1 5e-50 169.5 0.0 2.6 2 1 1 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 CDJ43278.1 - 9.8e-34 116.9 20.8 2.1e-32 112.5 20.8 2.3 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 CDJ43278.1 - 2.3e-19 69.5 3.6 1.1e-18 67.3 0.0 3.0 3 0 0 3 3 2 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CDJ43278.1 - 2.1e-18 66.7 0.1 9.3e-18 64.6 0.1 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDJ43278.1 - 4.3e-08 33.3 0.0 0.00027 21.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ43278.1 - 0.0013 19.2 1.7 0.3 11.5 0.0 4.0 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) DUF4407 PF14362.6 CDJ43278.1 - 0.045 13.1 17.6 0.11 11.8 6.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) UPF0565 PF10561.9 CDJ43278.1 - 0.29 10.3 5.0 0.13 11.4 1.9 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 PDCD7 PF16021.5 CDJ43278.1 - 2 7.4 25.3 0.0086 15.2 10.7 2.3 2 0 0 2 2 2 0 Programmed cell death protein 7 PRKG1_interact PF15898.5 CDJ43278.1 - 2.4 9.1 22.3 2.8 8.9 11.1 2.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Mac PF12464.8 CDJ43278.1 - 3.7 7.9 8.4 0.79 10.0 0.2 3.2 2 1 0 2 2 2 0 Maltose acetyltransferase LUC7 PF03194.15 CDJ43278.1 - 4.1 7.0 14.5 0.097 12.3 5.1 2.2 2 0 0 2 2 2 0 LUC7 N_terminus Spc7 PF08317.11 CDJ43278.1 - 4.3 6.1 27.9 2.6 6.8 4.0 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Tho2 PF11262.8 CDJ43278.1 - 4.5 6.4 12.3 2.5 7.2 5.1 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 ATP-synt_B PF00430.18 CDJ43278.1 - 9.1 6.4 33.5 1 9.4 14.1 2.5 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Laminin_I PF06008.14 CDJ43278.1 - 9.6 5.8 28.1 0.97 9.1 4.9 3.3 2 1 1 3 3 3 0 Laminin Domain I AAA_9 PF12781.7 CDJ43279.1 - 3.8e-51 173.3 0.0 4.8e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 ATP-binding dynein motor region Dynein_C PF18199.1 CDJ43280.1 - 8.3e-83 278.1 0.4 1.8e-82 277.0 0.0 1.8 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CDJ43280.1 - 2e-49 167.6 0.0 3.6e-49 166.7 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ43280.1 - 3.7e-36 123.8 0.0 1.6e-35 121.7 0.0 2.2 1 1 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_9 PF12781.7 CDJ43280.1 - 8.2e-11 41.5 7.1 1.5e-10 40.6 7.1 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region MbeB_N PF04837.12 CDJ43280.1 - 0.055 13.8 4.7 5.1 7.5 0.4 2.6 2 0 0 2 2 2 0 MbeB-like, N-term conserved region DUF2368 PF10166.9 CDJ43280.1 - 0.062 12.9 0.6 0.14 11.8 0.6 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Motilin_ghrelin PF04644.12 CDJ43280.1 - 0.65 9.8 1.9 0.72 9.7 0.1 2.0 2 0 0 2 2 2 0 Motilin/ghrelin DUF4795 PF16043.5 CDJ43280.1 - 1.3 8.5 8.4 3.9 7.0 7.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Spore_III_AB PF09548.10 CDJ43280.1 - 8.2 6.5 7.5 20 5.2 5.8 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) VPS13_C PF16909.5 CDJ43281.1 - 1.5e-16 60.7 0.0 2.8e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 CDJ43281.1 - 6.1e-13 48.8 0.0 5.7e-11 42.3 0.0 2.7 1 1 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 Elicitin PF00964.17 CDJ43281.1 - 0.051 13.7 0.5 0.13 12.3 0.5 1.7 1 0 0 1 1 1 0 Elicitin VPS13 PF16908.5 CDJ43285.1 - 4.4e-07 30.0 0.0 3.9e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal TPR_12 PF13424.6 CDJ43286.1 - 0.027 14.8 0.9 1.8 8.9 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Gp_dh_C PF02800.20 CDJ43289.1 - 7.6e-68 227.1 0.0 1e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CDJ43289.1 - 1.9e-38 130.8 0.0 4.4e-38 129.7 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CDJ43289.1 - 0.087 12.9 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ATP-synt_10 PF05176.14 CDJ43290.1 - 0.0024 17.1 0.0 0.44 9.7 0.0 2.1 2 0 0 2 2 2 2 ATP10 protein Psb28 PF03912.14 CDJ43290.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Psb28 protein DUF905 PF06006.12 CDJ43290.1 - 0.18 11.8 0.3 1.8 8.6 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) tRNA-synt_His PF13393.6 CDJ43291.1 - 2.1e-13 50.2 2.9 1e-05 25.0 0.2 3.9 3 1 1 4 4 4 2 Histidyl-tRNA synthetase Ribosomal_L7Ae PF01248.26 CDJ43292.1 - 4.6e-23 80.8 1.6 8.6e-23 79.9 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CDJ43292.1 - 0.03 14.4 0.1 0.056 13.5 0.1 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 Metallophos_2 PF12850.7 CDJ43293.1 - 8.6e-20 71.6 0.0 1.1e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CDJ43293.1 - 0.00038 21.0 2.5 0.0067 16.9 0.6 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase CHCH PF06747.13 CDJ43294.1 - 3e-05 24.0 1.5 5.4e-05 23.2 1.5 1.5 1 0 0 1 1 1 1 CHCH domain Pex14_N PF04695.13 CDJ43295.1 - 0.17 12.5 13.1 0.32 11.6 13.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-5_eIF-2B PF01873.17 CDJ43296.1 - 6.7e-35 119.5 0.6 3.6e-34 117.1 0.0 2.2 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 CDJ43296.1 - 4.7e-15 55.5 0.0 4.7e-15 55.5 0.0 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Nop14 PF04147.12 CDJ43296.1 - 0.34 9.1 20.9 0.46 8.6 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family Ndc1_Nup PF09531.10 CDJ43296.1 - 2.9 6.5 3.9 3.6 6.2 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ALMT PF11744.8 CDJ43296.1 - 3.2 6.5 7.9 4.3 6.0 7.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF913 PF06025.12 CDJ43296.1 - 5.5 5.9 7.4 8.9 5.2 7.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 CDJ43296.1 - 8.5 5.0 11.3 11 4.7 11.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 CDJ43296.1 - 9.7 4.3 16.8 14 3.9 16.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Paramyxo_ncap PF00973.19 CDJ43297.1 - 0.023 13.6 2.5 0.03 13.3 2.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein EAGR_box PF16713.5 CDJ43298.1 - 0.001 18.7 5.6 0.001 18.7 5.6 4.2 4 0 0 4 4 4 3 Enriched in aromatic and glycine Residues box PHD PF00628.29 CDJ43299.1 - 2.1e-07 30.7 3.9 7.3e-07 29.0 3.9 1.9 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 CDJ43299.1 - 5.1 7.3 5.8 25 5.1 5.8 2.3 1 0 0 1 1 1 0 PHD-finger UCH PF00443.29 CDJ43301.1 - 5.6e-28 98.1 0.0 5.6e-28 98.1 0.0 2.7 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ43301.1 - 3.8e-10 39.9 12.0 3.6e-06 26.8 0.0 3.6 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase AF-4 PF05110.13 CDJ43302.1 - 0.0064 14.7 4.6 0.0058 14.8 4.6 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein SR-25 PF10500.9 CDJ43302.1 - 0.032 13.8 8.1 0.036 13.7 8.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Gemini_V2 PF01524.17 CDJ43302.1 - 0.092 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Geminivirus V2 protein DUF755 PF05501.11 CDJ43302.1 - 2.1 8.6 16.8 2.4 8.4 16.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF755) PFK PF00365.20 CDJ43303.1 - 1.4 8.2 12.0 5.6 6.2 1.7 3.2 3 0 0 3 3 3 0 Phosphofructokinase RRM_1 PF00076.22 CDJ43306.1 - 7.7e-15 54.5 0.0 1.4e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ctr PF04145.15 CDJ43308.1 - 6.3e-16 59.3 13.0 1.8e-13 51.3 13.0 2.1 1 1 0 1 1 1 1 Ctr copper transporter family GLTP PF08718.11 CDJ43309.1 - 6.2e-24 85.0 0.0 7.8e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) SWIRM-assoc_2 PF16496.5 CDJ43310.1 - 0.52 9.1 10.8 0.77 8.6 10.8 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Reticulon PF02453.17 CDJ43312.1 - 3.5e-10 40.1 9.2 4.5e-10 39.7 8.5 1.4 1 1 0 1 1 1 1 Reticulon zf-PARP PF00645.18 CDJ43313.1 - 3.8e-07 30.9 0.1 1.2e-06 29.2 0.1 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region RAP1 PF07218.11 CDJ43313.1 - 5.7 5.1 6.4 7.4 4.7 6.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SNF2_N PF00176.23 CDJ43314.1 - 2e-16 59.7 0.1 2.2e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.23 CDJ43315.1 - 2.6e-21 75.7 0.2 1.2e-12 47.3 0.0 3.3 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ43315.1 - 5.8e-17 62.0 0.0 1.4e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 CDJ43315.1 - 6.4e-07 29.6 1.2 6.4e-07 29.6 1.2 2.9 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 CDJ43315.1 - 5e-05 23.5 1.4 5e-05 23.5 1.4 3.1 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ43315.1 - 8.9e-05 22.3 2.0 8.9e-05 22.3 2.0 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ43315.1 - 0.00025 21.0 0.1 0.00025 21.0 0.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ43315.1 - 0.00068 19.4 1.3 0.00068 19.4 1.3 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ43315.1 - 0.0014 18.6 0.7 0.0033 17.5 0.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CDJ43315.1 - 0.0019 17.9 4.2 0.0019 17.9 4.2 2.4 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 CDJ43315.1 - 0.0052 16.9 1.0 0.036 14.2 0.3 2.5 2 0 0 2 2 2 1 FANCL C-terminal domain UQ_con PF00179.26 CDJ43316.1 - 5.1e-44 149.3 0.0 6.4e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.26 CDJ43317.1 - 2e-15 56.7 0.0 3.2e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDJ43317.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain Vps36-NZF-N PF16988.5 CDJ43317.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain WD40 PF00400.32 CDJ43318.1 - 9.9e-15 54.7 8.3 0.00024 21.8 0.9 5.4 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ43318.1 - 1.2e-08 35.1 0.0 0.67 10.3 0.0 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 CDJ43318.1 - 0.0028 17.1 0.0 0.0065 15.9 0.0 1.6 1 0 0 1 1 1 1 EF hand PQQ PF01011.21 CDJ43318.1 - 0.017 15.1 2.0 54 4.0 0.0 4.4 4 0 0 4 4 4 0 PQQ enzyme repeat Nup160 PF11715.8 CDJ43318.1 - 0.1 11.2 0.1 5.2 5.6 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF5046 PF16465.5 CDJ43318.1 - 0.15 11.5 0.0 6.4 6.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) EF-hand_6 PF13405.6 CDJ43318.1 - 0.18 11.8 0.0 0.51 10.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain PQQ_3 PF13570.6 CDJ43318.1 - 2.3 8.8 5.1 8.3 7.1 0.0 3.9 5 0 0 5 5 5 0 PQQ-like domain RCC1_2 PF13540.6 CDJ43319.1 - 4.2e-12 45.5 24.5 0.00024 20.8 0.4 5.9 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CDJ43319.1 - 7.5e-12 45.7 17.4 5.6e-05 23.7 1.3 7.2 7 1 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat PDEase_I PF00233.19 CDJ43320.1 - 1.3e-59 201.8 6.3 3.4e-29 102.2 0.0 2.4 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase CBM_48 PF02922.18 CDJ43321.1 - 5.8e-22 77.9 0.0 1.5e-20 73.4 0.0 3.0 3 0 0 3 3 3 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 CDJ43321.1 - 3.1e-19 69.2 0.0 1.8e-18 66.8 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 CDJ43321.1 - 2.4e-13 50.4 0.8 0.00011 21.9 0.1 3.2 2 1 1 3 3 3 3 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 CDJ43321.1 - 0.0079 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DND1_DSRM PF14709.7 CDJ43322.1 - 0.49 10.7 4.8 1.8 8.9 0.0 3.3 3 0 0 3 3 3 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsRBD2 PF17842.1 CDJ43322.1 - 2 8.6 10.5 0.56 10.4 0.4 3.1 3 0 0 3 3 3 0 Double-stranded RNA binding domain 2 DUF45 PF01863.17 CDJ43322.1 - 2.4 8.1 7.3 1.3 9.0 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF45 Med26_C PF15693.5 CDJ43322.1 - 5.5 7.1 9.2 1.6 8.9 3.6 2.5 2 0 0 2 2 2 0 Mediator complex subunit 26 C-terminal OB_NTP_bind PF07717.16 CDJ43323.1 - 8.9e-17 61.2 0.0 2e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ43323.1 - 7.7e-14 52.0 0.0 1.8e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 CDJ43323.1 - 5.5e-13 49.1 1.0 1.6e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 CDJ43323.1 - 3.6e-08 33.4 0.1 6.8e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ43323.1 - 0.00011 22.5 0.1 0.00027 21.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ43323.1 - 0.0032 17.2 0.1 0.0086 15.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDJ43323.1 - 0.011 14.9 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 CDJ43323.1 - 0.02 15.3 1.0 0.043 14.2 0.2 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CDJ43323.1 - 0.022 14.0 0.1 0.042 13.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 CDJ43323.1 - 0.045 14.1 0.4 0.29 11.5 0.4 2.4 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 CDJ43323.1 - 0.053 13.5 0.0 1.1 9.3 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 CDJ43323.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 CDJ43323.1 - 0.093 12.5 1.8 7.2 6.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain Tyr_Deacylase PF02580.16 CDJ43324.1 - 6.5e-46 156.4 0.0 8e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase C2 PF00168.30 CDJ43325.1 - 1.9e-12 47.4 0.1 4.9e-10 39.6 0.0 3.5 3 0 0 3 3 3 2 C2 domain TFIIA PF03153.13 CDJ43326.1 - 0.031 14.3 31.0 0.038 14.0 31.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ43326.1 - 0.047 12.0 20.5 0.046 12.0 20.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SID-1_RNA_chan PF13965.6 CDJ43326.1 - 0.067 11.6 4.4 0.087 11.2 4.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ43326.1 - 0.093 11.6 3.7 0.1 11.5 3.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) VIR_N PF15912.5 CDJ43326.1 - 0.1 12.2 3.4 0.12 12.0 3.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Ctr PF04145.15 CDJ43326.1 - 0.21 12.2 10.5 0.34 11.5 10.5 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Exonuc_VII_L PF02601.15 CDJ43326.1 - 0.25 10.8 14.5 0.25 10.9 14.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit NARP1 PF12569.8 CDJ43326.1 - 0.54 9.1 19.0 0.7 8.7 19.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4446 PF14584.6 CDJ43326.1 - 0.59 10.1 8.0 0.83 9.6 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Connexin PF00029.19 CDJ43326.1 - 0.88 9.3 10.1 1.1 9.0 10.1 1.2 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 CDJ43326.1 - 1.3 8.0 11.3 1.5 7.7 11.3 1.1 1 0 0 1 1 1 0 CLN3 protein Peptidase_U57 PF05582.12 CDJ43326.1 - 1.3 8.2 11.1 1.6 7.9 11.1 1.1 1 0 0 1 1 1 0 YabG peptidase U57 RR_TM4-6 PF06459.12 CDJ43326.1 - 1.5 8.6 16.0 1.8 8.3 16.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.10 CDJ43326.1 - 1.5 8.9 17.7 2.1 8.4 17.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DDHD PF02862.17 CDJ43326.1 - 2 8.5 13.4 2.6 8.1 13.4 1.2 1 0 0 1 1 1 0 DDHD domain Methyltransf_32 PF13679.6 CDJ43326.1 - 2 8.4 11.5 3 7.8 11.5 1.3 1 0 0 1 1 1 0 Methyltransferase domain Presenilin PF01080.17 CDJ43326.1 - 2.4 6.8 18.9 3.4 6.3 18.9 1.2 1 0 0 1 1 1 0 Presenilin CSG2 PF16965.5 CDJ43326.1 - 3.2 6.6 7.4 3.8 6.3 7.4 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator V_ATPase_I PF01496.19 CDJ43326.1 - 4.1 5.2 14.5 4.7 5.0 14.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MMR1 PF08505.10 CDJ43326.1 - 4.1 7.6 18.4 6.3 7.0 18.4 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein BT1 PF03092.16 CDJ43326.1 - 4.5 5.4 5.5 5.9 5.0 5.5 1.2 1 0 0 1 1 1 0 BT1 family O-antigen_lig PF13425.6 CDJ43326.1 - 5.7 5.6 6.5 7.4 5.2 6.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF2828 PF11443.8 CDJ43326.1 - 5.8 4.9 22.3 1.6 6.7 19.6 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Band_3_cyto PF07565.13 CDJ43326.1 - 7.2 6.3 14.4 8.9 6.0 14.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ORC_WH_C PF18137.1 CDJ43326.1 - 8.6 6.4 16.4 13 5.8 16.4 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal RabGAP-TBC PF00566.18 CDJ43328.1 - 1.6e-18 67.2 0.0 2.6e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Utp11 PF03998.13 CDJ43328.1 - 0.19 11.6 3.0 0.29 11.0 3.0 1.2 1 0 0 1 1 1 0 Utp11 protein RskA PF10099.9 CDJ43328.1 - 1.6 9.0 15.1 0.49 10.7 9.8 2.3 2 1 0 2 2 2 0 Anti-sigma-K factor rskA BAF1_ABF1 PF04684.13 CDJ43328.1 - 2.1 7.3 17.2 0.013 14.6 7.2 1.8 1 1 1 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor WD40 PF00400.32 CDJ43329.1 - 4e-14 52.8 0.0 0.00052 20.8 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat TAF4 PF05236.14 CDJ43329.1 - 0.058 13.1 1.0 0.1 12.3 1.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family zf-CCHC PF00098.23 CDJ43332.1 - 1.1e-05 25.3 3.3 2.4e-05 24.2 3.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ43332.1 - 0.0022 17.8 1.9 0.0022 17.8 1.9 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ43332.1 - 0.032 14.2 0.6 0.087 12.8 0.6 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ43332.1 - 0.042 13.6 0.8 0.081 12.7 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 CDJ43332.1 - 0.05 13.9 0.0 0.64 10.3 0.0 2.5 3 0 0 3 3 3 0 Retrotransposon gag protein DUF1281 PF06924.11 CDJ43332.1 - 0.12 11.9 0.0 7.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) zf-CCHC_2 PF13696.6 CDJ43332.1 - 0.31 10.9 5.6 0.2 11.5 3.4 1.9 2 0 0 2 2 2 0 Zinc knuckle GTSE1_N PF15259.6 CDJ43333.1 - 0.01 16.0 0.3 0.023 14.9 0.3 1.5 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 DSHCT PF08148.12 CDJ43335.1 - 0.021 14.5 0.2 0.15 11.7 0.1 2.2 1 1 1 2 2 2 0 DSHCT (NUC185) domain DUF1192 PF06698.11 CDJ43335.1 - 0.17 11.9 0.8 0.93 9.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Retrotrans_gag PF03732.17 CDJ43337.1 - 0.0054 17.0 0.0 0.048 13.9 0.0 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein Peptidase_M3_N PF08439.10 CDJ43338.1 - 0.023 14.9 0.1 0.055 13.8 0.1 1.6 1 0 0 1 1 1 0 Oligopeptidase F Isochorismatase PF00857.20 CDJ43339.1 - 2.9e-25 89.4 1.0 1.5e-19 70.8 0.9 2.2 2 0 0 2 2 2 2 Isochorismatase family Helicase_C_2 PF13307.6 CDJ43340.1 - 4.7e-39 134.3 0.0 1.2e-37 129.7 0.0 2.6 1 1 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CDJ43340.1 - 3.1e-30 105.1 1.4 1.4e-29 103.0 0.0 2.2 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 CDJ43340.1 - 0.003 17.6 0.0 2.6 8.0 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ43340.1 - 0.011 15.5 0.0 0.051 13.3 0.0 2.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase SUIM_assoc PF16619.5 CDJ43341.1 - 0.14 12.3 0.1 0.14 12.3 0.1 14.6 9 4 2 11 11 11 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 CDJ43342.1 - 7.9e-36 123.8 0.0 7.9e-36 123.8 0.0 3.3 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ43342.1 - 4.9e-25 88.3 0.0 4.9e-25 88.3 0.0 3.9 3 1 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ43343.1 - 2.3e-20 73.1 0.1 4.2e-15 55.8 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ43343.1 - 5.3e-10 39.0 0.0 0.00048 19.5 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase FH2 PF02181.23 CDJ43345.1 - 1.6e-05 24.2 0.2 1.6e-05 24.2 0.2 3.5 2 1 2 4 4 4 1 Formin Homology 2 Domain Cep57_CLD_2 PF14197.6 CDJ43345.1 - 0.00024 21.1 0.4 0.00024 21.1 0.4 4.8 4 1 0 4 4 4 1 Centrosome localisation domain of PPC89 PKcGMP_CC PF16808.5 CDJ43345.1 - 2.4 8.1 7.5 19 5.2 3.4 3.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ELO PF01151.18 CDJ43346.1 - 3e-46 158.0 22.7 3.9e-46 157.6 22.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family TPH PF13868.6 CDJ43348.1 - 1.7e-26 92.6 151.7 1.7e-26 92.6 151.7 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain DEAD PF00270.29 CDJ43349.1 - 6.9e-46 156.2 0.0 1.5e-45 155.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ43349.1 - 8.4e-22 77.6 0.0 6.5e-21 74.8 0.0 2.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CDJ43349.1 - 1.1e-18 67.2 0.3 2.2e-18 66.2 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CDJ43349.1 - 0.00032 20.7 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4813 PF16072.5 CDJ43349.1 - 0.76 9.4 13.4 1.1 8.8 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Roughex PF06020.11 CDJ43349.1 - 5.3 6.0 10.5 8.3 5.4 10.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Spore_coat_CotO PF14153.6 CDJ43349.1 - 9.6 6.1 10.8 17 5.3 10.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Bromodomain PF00439.25 CDJ43350.1 - 6e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain AAA_16 PF13191.6 CDJ43351.1 - 0.0034 17.8 6.6 0.0034 17.8 6.6 4.6 4 2 0 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 CDJ43351.1 - 0.045 13.5 0.1 0.18 11.6 0.1 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain TRAPP PF04051.16 CDJ43352.1 - 2.4e-28 98.7 0.0 3.2e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF3793 PF12672.7 CDJ43352.1 - 0.17 11.9 0.0 0.17 11.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3793) Exonuc_VII_L PF02601.15 CDJ43353.1 - 0.00021 21.0 11.0 0.00021 21.0 11.0 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit BAF1_ABF1 PF04684.13 CDJ43353.1 - 0.00078 18.6 10.6 0.00078 18.6 10.6 1.9 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor eIF-3_zeta PF05091.12 CDJ43353.1 - 0.00093 18.3 24.4 0.0011 18.0 24.4 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Endostatin PF06482.11 CDJ43353.1 - 0.0015 18.1 15.3 0.0019 17.7 15.3 1.2 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin CDC45 PF02724.14 CDJ43353.1 - 0.0045 15.3 17.8 0.0056 15.0 17.8 1.1 1 0 0 1 1 1 1 CDC45-like protein PA26 PF04636.13 CDJ43353.1 - 0.0072 15.3 11.3 0.0081 15.1 11.3 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) SAPS PF04499.15 CDJ43353.1 - 0.0092 14.8 11.0 0.01 14.7 11.0 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein CPSF100_C PF13299.6 CDJ43353.1 - 0.0094 16.2 14.3 0.0094 16.2 14.3 1.8 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal MCM_bind PF09739.9 CDJ43353.1 - 0.011 14.2 15.7 0.013 14.0 15.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SID-1_RNA_chan PF13965.6 CDJ43353.1 - 0.016 13.7 5.3 0.016 13.7 5.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAT1 PF09770.9 CDJ43353.1 - 0.024 12.9 38.8 0.03 12.6 38.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Paf1 PF03985.13 CDJ43353.1 - 0.046 12.7 24.9 0.065 12.2 24.9 1.2 1 0 0 1 1 1 0 Paf1 LMBR1 PF04791.16 CDJ43353.1 - 0.057 12.3 7.4 0.051 12.5 7.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF913 PF06025.12 CDJ43353.1 - 0.13 11.2 12.9 0.19 10.7 12.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4638 PF15472.6 CDJ43353.1 - 0.14 11.9 17.5 0.2 11.4 17.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Velvet PF11754.8 CDJ43353.1 - 0.14 12.0 22.5 0.053 13.4 19.6 1.6 2 0 0 2 2 2 0 Velvet factor FAM60A PF15396.6 CDJ43353.1 - 0.3 11.1 20.8 0.016 15.2 15.2 1.7 2 0 0 2 2 2 0 Protein Family FAM60A SpoIIP PF07454.11 CDJ43353.1 - 0.32 10.4 25.6 0.6 9.5 25.6 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 CDJ43353.1 - 0.33 9.7 22.7 0.46 9.2 22.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 LAP1C PF05609.12 CDJ43353.1 - 0.33 10.0 24.0 0.47 9.5 24.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) NPR3 PF03666.13 CDJ43353.1 - 0.38 9.5 24.9 0.59 8.9 24.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CDJ43353.1 - 0.4 9.4 33.1 0.68 8.6 33.1 1.3 1 0 0 1 1 1 0 Presenilin DUF5427 PF10310.9 CDJ43353.1 - 0.5 9.3 27.0 0.79 8.6 27.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) TFIIA PF03153.13 CDJ43353.1 - 0.61 10.0 59.4 1.4 8.8 59.4 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 CDJ43353.1 - 0.83 7.7 23.4 1.1 7.3 23.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2151 PF10221.9 CDJ43353.1 - 0.99 7.9 13.4 1.3 7.5 13.4 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Gti1_Pac2 PF09729.9 CDJ43353.1 - 1.1 9.3 24.6 1.1 9.4 23.2 1.6 2 0 0 2 2 2 0 Gti1/Pac2 family DUF3027 PF11228.8 CDJ43353.1 - 1.2 9.1 10.5 1.7 8.6 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) NARP1 PF12569.8 CDJ43353.1 - 1.3 7.8 27.3 1.8 7.3 27.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SLC12 PF03522.15 CDJ43353.1 - 1.4 7.8 28.5 2 7.4 28.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF3807 PF12720.7 CDJ43353.1 - 1.5 9.0 36.0 0.14 12.4 31.3 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF3807) SAGA-Tad1 PF12767.7 CDJ43353.1 - 1.8 8.3 22.3 2.4 7.8 21.6 1.5 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2126 PF09899.9 CDJ43353.1 - 1.9 6.5 19.1 2.4 6.1 19.1 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF2370 PF10176.9 CDJ43353.1 - 2.4 7.7 13.5 3.6 7.2 13.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) V_ATPase_I PF01496.19 CDJ43353.1 - 3.4 5.5 29.4 4.4 5.1 29.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lin-8 PF03353.15 CDJ43353.1 - 4.2 6.9 32.2 7 6.1 32.3 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BORG_CEP PF14957.6 CDJ43353.1 - 4.2 8.5 21.9 4.7 8.4 20.2 1.8 2 0 0 2 2 2 0 Cdc42 effector DUF4776 PF16003.5 CDJ43353.1 - 4.3 6.2 25.4 5.9 5.8 25.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) MDM10 PF12519.8 CDJ43353.1 - 4.6 6.0 23.9 6.7 5.5 23.9 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 GREB1 PF15782.5 CDJ43353.1 - 4.7 4.2 26.6 6.2 3.8 26.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_U57 PF05582.12 CDJ43353.1 - 4.7 6.4 16.3 7.8 5.7 16.3 1.4 1 0 0 1 1 1 0 YabG peptidase U57 CCSAP PF15748.5 CDJ43353.1 - 7.1 6.7 34.6 3.1 7.9 31.6 1.7 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Hamartin PF04388.12 CDJ43353.1 - 7.2 5.1 23.9 2.4 6.7 21.5 1.4 2 0 0 2 2 2 0 Hamartin protein Peptidase_S64 PF08192.11 CDJ43353.1 - 7.2 5.0 25.8 12 4.2 25.8 1.3 1 0 0 1 1 1 0 Peptidase family S64 Neur_chan_memb PF02932.16 CDJ43353.1 - 7.4 6.6 25.3 13 5.8 25.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Membralin PF09746.9 CDJ43353.1 - 8.3 5.3 18.5 11 4.9 18.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF4569 PF15133.6 CDJ43353.1 - 8.4 6.0 27.1 14 5.3 27.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Plasmodium_Vir PF05795.11 CDJ43353.1 - 9.2 5.6 15.6 0.71 9.2 11.2 1.5 2 0 0 2 2 1 0 Plasmodium vivax Vir protein Sin_N PF04801.13 CDJ43353.1 - 9.6 5.3 46.6 15 4.7 46.6 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Band_3_cyto PF07565.13 CDJ43353.1 - 9.7 5.9 24.3 17 5.1 24.3 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Alg14 PF08660.11 CDJ43354.1 - 2.8e-09 37.1 0.0 5.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF1712 PF08217.11 CDJ43355.1 - 1.4e-14 53.6 0.0 4.1e-12 45.4 0.0 2.2 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) DUF2057 PF09829.9 CDJ43355.1 - 0.029 14.5 1.2 0.029 14.5 1.2 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Rad54_N PF08658.10 CDJ43355.1 - 0.061 13.5 0.2 2.3 8.4 0.1 2.5 2 1 0 2 2 2 0 Rad54 N terminal TFIIA PF03153.13 CDJ43355.1 - 0.67 9.9 10.7 0.95 9.4 10.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ43355.1 - 2.4 6.9 4.9 3.6 6.2 4.9 1.2 1 0 0 1 1 1 0 Presenilin RIFIN PF02009.16 CDJ43355.1 - 3.9 7.3 5.1 6 6.7 5.1 1.3 1 0 0 1 1 1 0 Rifin DUF572 PF04502.13 CDJ43355.1 - 4.3 6.9 7.5 6.4 6.3 7.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) LRR_9 PF14580.6 CDJ43356.1 - 9.2e-59 197.8 0.2 1.4e-58 197.2 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CDJ43356.1 - 1.4e-06 28.5 7.0 0.0071 16.7 1.7 3.8 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ43356.1 - 5.6e-06 26.0 0.6 5.6e-06 26.0 0.6 2.3 2 0 0 2 2 2 1 Leucine rich repeat TPR_7 PF13176.6 CDJ43356.1 - 0.0017 18.3 0.2 0.052 13.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ43356.1 - 0.0062 17.1 3.1 0.54 11.0 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ43356.1 - 0.014 15.5 0.0 0.062 13.6 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Adeno_PIX PF03955.14 CDJ43356.1 - 4.4 7.5 7.5 8.5 6.6 0.5 2.5 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) dUTPase PF00692.19 CDJ43357.1 - 2.3e-16 59.6 0.0 3.2e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 dUTPase Atrophin-1 PF03154.15 CDJ43357.1 - 1.5 7.0 5.3 1.7 6.8 5.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family EF-hand_7 PF13499.6 CDJ43358.1 - 2.3e-10 40.8 0.1 0.0013 19.1 0.0 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ43358.1 - 2.3e-09 36.4 1.9 0.0022 17.8 1.2 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDJ43358.1 - 1.6e-06 27.2 0.2 0.01 15.3 0.8 2.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CDJ43358.1 - 0.024 14.4 0.2 9 6.2 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 CDJ43358.1 - 0.028 13.9 3.8 0.15 11.6 0.2 2.6 3 0 0 3 3 3 0 EF hand DUF1456 PF07308.13 CDJ43358.1 - 0.038 14.3 0.1 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) DUF5580 PF17743.1 CDJ43358.1 - 0.096 11.2 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Tcp10_C PF07202.13 CDJ43359.1 - 5.3e-17 62.3 0.0 2.1e-16 60.4 0.0 2.0 1 0 0 1 1 1 1 T-complex protein 10 C-terminus SNase PF00565.17 CDJ43360.1 - 5.3e-37 126.6 1.2 3.5e-14 53.2 0.0 4.6 4 1 0 4 4 4 3 Staphylococcal nuclease homologue TUDOR PF00567.24 CDJ43360.1 - 6.8e-21 74.5 0.0 2.2e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 Tudor domain Agenet PF05641.12 CDJ43360.1 - 5.2e-05 23.6 0.1 0.0027 18.2 0.0 3.2 3 0 0 3 3 3 1 Agenet domain bMG10 PF17973.1 CDJ43360.1 - 0.00043 20.5 0.1 1.8 8.8 0.0 3.1 3 0 0 3 3 3 2 Bacterial Alpha-2-macroglobulin MG10 domain Iron_permease PF04120.12 CDJ43360.1 - 0.2 11.4 0.3 23 4.8 0.0 2.6 2 0 0 2 2 2 0 Low affinity iron permease TruD PF01142.18 CDJ43361.1 - 8.4e-48 163.2 0.2 1.2e-44 152.8 0.0 4.1 3 2 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) AAA_23 PF13476.6 CDJ43361.1 - 0.25 11.8 21.9 3.4 8.1 8.9 4.1 4 0 0 4 4 4 0 AAA domain HEAT PF02985.22 CDJ43361.1 - 0.42 11.0 3.6 2.9 8.4 0.5 3.9 2 0 0 2 2 2 0 HEAT repeat HEM4 PF02602.15 CDJ43362.1 - 4.4e-11 42.6 25.5 4.9e-06 26.1 11.2 4.3 4 1 0 4 4 4 3 Uroporphyrinogen-III synthase HemD SNAPc_SNAP43 PF09808.9 CDJ43363.1 - 0.0002 21.4 0.3 0.014 15.4 0.0 3.0 3 0 0 3 3 3 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DUF2722 PF10846.8 CDJ43363.1 - 0.0014 17.7 4.6 0.0014 17.7 4.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ43363.1 - 0.0026 17.8 2.7 0.0047 17.0 2.7 1.4 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) V_ATPase_I PF01496.19 CDJ43363.1 - 0.38 8.6 1.1 0.58 8.0 1.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SelP_N PF04592.14 CDJ43363.1 - 0.65 9.4 7.1 1.1 8.6 7.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Stathmin PF00836.19 CDJ43365.1 - 0.00047 20.1 10.1 0.00047 20.1 10.1 2.5 2 0 0 2 2 2 1 Stathmin family Apolipoprotein PF01442.18 CDJ43365.1 - 0.7 9.7 19.7 0.063 13.1 6.4 2.7 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain Kelch_5 PF13854.6 CDJ43366.1 - 2.8e-12 46.3 1.8 4.9e-08 32.8 0.1 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CDJ43366.1 - 1.6e-11 44.0 7.5 2.1e-05 24.4 0.2 4.8 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ43366.1 - 4.6e-09 36.3 0.3 4.6e-09 36.3 0.3 3.0 2 1 1 3 3 3 1 Kelch motif Kelch_2 PF07646.15 CDJ43366.1 - 7e-09 35.3 1.7 5.4e-05 23.0 1.2 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 CDJ43366.1 - 8.2e-09 34.9 1.7 8.2e-09 34.9 1.7 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 CDJ43366.1 - 1.8e-08 34.5 0.4 7.9e-05 22.8 0.1 4.2 3 0 0 3 3 3 2 Galactose oxidase, central domain TPR_14 PF13428.6 CDJ43369.1 - 1.2 10.1 0.0 1.2 10.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4549 PF15082.6 CDJ43373.1 - 0.15 11.8 0.1 0.43 10.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) WD40 PF00400.32 CDJ43374.1 - 2.1e-09 37.8 7.3 2.5e-05 24.9 0.2 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Hira PF07569.11 CDJ43374.1 - 0.068 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 TUP1-like enhancer of split Ribosomal_60s PF00428.19 CDJ43374.1 - 6.3 7.5 16.3 3.6 8.3 4.2 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein PH_10 PF15411.6 CDJ43375.1 - 0.045 14.0 0.0 8.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain TFIIA PF03153.13 CDJ43375.1 - 0.47 10.4 10.1 4.9 7.0 5.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ43375.1 - 0.5 11.3 3.6 0.85 10.6 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DnaJ PF00226.31 CDJ43376.1 - 2e-15 56.6 0.0 3.1e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF2052 PF09747.9 CDJ43377.1 - 6.1e-27 95.0 74.4 1.2e-11 45.1 50.4 4.3 2 1 1 3 3 3 3 Coiled-coil domain containing protein (DUF2052) Pal1 PF08316.11 CDJ43377.1 - 0.00016 22.4 2.7 0.00016 22.4 2.7 4.9 3 1 1 4 4 4 1 Pal1 cell morphology protein SR-25 PF10500.9 CDJ43377.1 - 0.0013 18.4 15.7 0.0013 18.4 15.7 4.2 3 1 1 4 4 4 3 Nuclear RNA-splicing-associated protein DUF4071 PF13281.6 CDJ43378.1 - 0.028 13.5 11.7 0.051 12.6 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) PIN_8 PF18476.1 CDJ43378.1 - 0.12 12.2 13.4 0.32 10.8 13.4 1.7 1 0 0 1 1 1 0 PIN like domain DUF4954 PF16314.5 CDJ43378.1 - 0.13 10.3 2.6 0.19 9.8 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) AAA_32 PF13654.6 CDJ43378.1 - 0.16 10.7 18.4 0.28 9.9 18.4 1.3 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 CDJ43378.1 - 0.21 10.2 10.0 0.35 9.4 10.0 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A WASH-7_mid PF14744.6 CDJ43378.1 - 0.21 10.6 5.5 0.36 9.9 5.5 1.3 1 0 0 1 1 1 0 WASH complex subunit 7 RNase_E_G PF10150.9 CDJ43378.1 - 0.33 10.3 10.5 0.59 9.5 10.5 1.4 1 0 0 1 1 1 0 Ribonuclease E/G family Peptidase_Prp PF04327.12 CDJ43378.1 - 0.39 11.0 4.2 1.3 9.4 4.2 1.9 1 0 0 1 1 1 0 Cysteine protease Prp RHD3 PF05879.12 CDJ43378.1 - 0.63 8.1 10.4 0.92 7.6 10.4 1.2 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) ZYG-11_interact PF05884.12 CDJ43378.1 - 1.2 8.4 18.4 0.5 9.7 15.1 1.9 2 0 0 2 2 2 0 Interactor of ZYG-11 AI-2E_transport PF01594.16 CDJ43378.1 - 1.2 8.2 3.2 2.2 7.4 3.2 1.3 1 0 0 1 1 1 0 AI-2E family transporter Prominin PF05478.11 CDJ43378.1 - 1.9 6.3 13.6 3.2 5.6 13.6 1.3 1 0 0 1 1 1 0 Prominin CorA PF01544.18 CDJ43378.1 - 1.9 7.7 7.2 4 6.7 7.2 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4795 PF16043.5 CDJ43378.1 - 2.4 7.7 25.7 31 4.1 25.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF2115 PF09888.9 CDJ43378.1 - 2.8 8.5 6.8 2.8 8.4 4.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF4837 PF16125.5 CDJ43378.1 - 3.7 6.5 9.3 6.1 5.8 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) Tam41_Mmp37 PF09139.11 CDJ43378.1 - 3.9 6.8 10.5 10 5.4 10.5 1.7 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial DUF668 PF05003.12 CDJ43378.1 - 4.2 7.9 9.2 13 6.3 8.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF668) dCache_2 PF08269.11 CDJ43378.1 - 5.8 6.0 13.3 11 5.1 13.3 1.4 1 0 0 1 1 1 0 Cache domain YpjP PF14005.6 CDJ43378.1 - 6.2 6.9 6.5 13 5.8 6.5 1.5 1 0 0 1 1 1 0 YpjP-like protein DUF2294 PF10057.9 CDJ43378.1 - 7.3 6.8 11.6 1.3 9.1 7.6 1.9 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2294) DUF2722 PF10846.8 CDJ43379.1 - 0.013 14.5 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ43379.1 - 0.019 14.6 3.4 0.027 14.1 3.4 1.2 1 0 0 1 1 1 0 Spt20 family Pinin_SDK_memA PF04696.13 CDJ43379.1 - 0.025 14.6 2.5 0.025 14.6 2.5 2.3 3 0 0 3 3 3 0 pinin/SDK/memA/ protein conserved region Inj_translocase PF16928.5 CDJ43379.1 - 0.037 13.5 5.6 0.053 13.0 5.6 1.2 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome DUF945 PF06097.11 CDJ43379.1 - 0.046 12.8 1.8 0.074 12.1 1.8 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) SUIM_assoc PF16619.5 CDJ43379.1 - 1.4 9.0 12.0 3.3 7.9 12.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SDP_N PF12278.8 CDJ43380.1 - 0.0012 19.0 9.0 0.0012 19.0 9.0 4.6 5 2 1 6 6 6 1 Sex determination protein N terminal SR-25 PF10500.9 CDJ43380.1 - 0.0075 15.9 10.8 0.0075 15.9 10.8 3.5 4 1 0 4 4 4 1 Nuclear RNA-splicing-associated protein WD40 PF00400.32 CDJ43381.1 - 1.7e-10 41.3 1.8 0.0026 18.6 0.0 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ43381.1 - 0.0001 22.5 0.0 0.0061 16.8 0.0 3.5 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain FliD_N PF02465.18 CDJ43381.1 - 0.0031 18.2 3.7 0.0031 18.2 3.7 3.0 3 0 0 3 3 3 1 Flagellar hook-associated protein 2 N-terminus RAB3GAP2_N PF14655.6 CDJ43381.1 - 0.038 13.2 0.0 0.038 13.2 0.0 3.6 3 1 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Duffy_binding PF05424.11 CDJ43381.1 - 0.043 13.9 0.1 0.043 13.9 0.1 2.4 3 0 0 3 3 3 0 Duffy binding domain DUF3592 PF12158.8 CDJ43381.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) DUF4834 PF16118.5 CDJ43381.1 - 0.11 13.5 7.3 0.47 11.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Acetyltransf_1 PF00583.25 CDJ43382.1 - 2.7e-06 27.6 0.1 5.9e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ43382.1 - 7e-05 23.2 0.0 0.0002 21.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ43382.1 - 0.0069 16.3 0.3 0.036 14.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GIDA PF01134.22 CDJ43383.1 - 1.6e-65 221.8 0.0 2.4e-43 148.7 0.1 2.1 1 1 1 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CDJ43383.1 - 0.00053 19.3 2.7 0.0092 15.2 1.7 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDJ43383.1 - 0.022 14.8 1.8 1.2 9.1 0.0 2.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glyco_transf_4 PF13439.6 CDJ43383.1 - 0.073 13.1 0.6 2.7 8.0 0.3 2.5 2 1 0 2 2 2 0 Glycosyltransferase Family 4 DAO PF01266.24 CDJ43383.1 - 0.096 12.2 11.6 0.027 14.0 0.7 2.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CDJ43383.1 - 0.13 11.6 15.8 0.0093 15.4 10.4 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDJ43383.1 - 0.15 11.1 19.8 0.11 11.5 7.7 2.8 1 1 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 CDJ43383.1 - 0.25 10.6 0.1 0.74 9.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ43383.1 - 2.1 9.0 3.5 4.1 8.0 2.7 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cytochrom_C PF00034.21 CDJ43384.1 - 2e-12 48.0 0.0 2.6e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CDJ43384.1 - 5.3e-06 26.7 2.4 1.3e-05 25.4 2.4 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CDJ43384.1 - 0.0034 17.1 0.0 0.0087 15.8 0.0 1.6 2 0 0 2 2 2 1 Cytochrome c-550 domain Haem_bd PF14376.6 CDJ43384.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Haem-binding domain Ferrochelatase PF00762.19 CDJ43385.1 - 3e-66 223.7 0.0 1.7e-65 221.2 0.0 2.0 1 1 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 CDJ43385.1 - 0.14 12.5 1.3 2.2 8.7 0.0 2.7 3 0 0 3 3 3 0 CbiX SelP_N PF04592.14 CDJ43385.1 - 0.22 10.9 10.5 0.38 10.1 10.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Vac7 PF12751.7 CDJ43385.1 - 6.4 6.1 8.7 9.2 5.6 8.7 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Herpes_UL6 PF01763.16 CDJ43386.1 - 0.085 11.4 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Kinesin PF00225.23 CDJ43387.1 - 3e-105 351.8 0.1 3e-105 351.8 0.1 1.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ43387.1 - 9.9e-27 93.7 0.0 2.2e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DKCLD PF08068.12 CDJ43388.1 - 2.2e-28 98.1 0.1 5e-28 96.9 0.1 1.7 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_N PF01509.18 CDJ43388.1 - 1e-24 87.6 0.8 9.2e-22 78.0 0.8 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 CDJ43388.1 - 1.9e-21 75.8 0.9 3.6e-21 74.9 0.9 1.5 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 CDJ43388.1 - 9.7e-21 73.7 0.7 1.7e-20 72.9 0.7 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UPF0113 PF03657.13 CDJ43388.1 - 0.0032 17.7 0.1 0.01 16.1 0.0 2.0 2 0 0 2 2 2 1 UPF0113 PUA domain Evr1_Alr PF04777.13 CDJ43391.1 - 3.8e-09 36.9 2.4 2.9e-06 27.7 1.7 3.5 2 1 0 2 2 2 2 Erv1 / Alr family Thioredoxin PF00085.20 CDJ43391.1 - 1.1e-07 31.8 0.0 2.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CDJ43391.1 - 0.11 12.7 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Zn_Tnp_IS1595 PF12760.7 CDJ43391.1 - 4 7.5 10.7 1.5 8.8 0.8 3.9 5 0 0 5 5 5 0 Transposase zinc-ribbon domain Microvir_J PF04726.13 CDJ43392.1 - 0.012 15.5 0.2 10 6.2 0.0 2.9 2 0 0 2 2 2 0 Microvirus J protein TMP_2 PF06791.13 CDJ43392.1 - 0.14 11.8 7.7 3 7.5 0.9 2.5 2 0 0 2 2 2 0 Prophage tail length tape measure protein Phage_holin_7_1 PF16081.5 CDJ43392.1 - 6.1 7.0 10.3 18 5.5 1.7 2.6 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF282 PF03380.14 CDJ43393.1 - 0.89 9.5 6.6 5.1 7.1 0.7 2.4 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 LRR19-TM PF15176.6 CDJ43397.1 - 0.13 12.3 0.1 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain zf-C2H2_4 PF13894.6 CDJ43398.1 - 0.033 15.0 0.4 0.033 15.0 0.4 3.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ43398.1 - 0.074 13.5 1.1 0.27 11.8 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type MAP65_ASE1 PF03999.12 CDJ43399.1 - 0.15 10.7 3.7 0.23 10.1 3.7 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TFIIA PF03153.13 CDJ43400.1 - 4 7.3 31.4 6.7 6.6 31.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ43400.1 - 6.6 5.2 21.6 9.5 4.6 21.6 1.2 1 0 0 1 1 1 0 Macoilin family HCMV_UL139 PF12507.8 CDJ43403.1 - 0.015 15.7 0.4 0.015 15.7 0.4 2.1 2 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein Mod_r PF07200.13 CDJ43403.1 - 0.02 15.0 0.4 0.02 15.0 0.4 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TMF_DNA_bd PF12329.8 CDJ43403.1 - 0.42 10.7 7.9 0.19 11.7 2.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.11 CDJ43403.1 - 9.4 6.5 6.9 32 4.8 0.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 AAA_16 PF13191.6 CDJ43405.1 - 3.5e-07 30.7 8.0 3.5e-07 30.7 8.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 CDJ43405.1 - 2.5e-06 27.8 0.8 2.5e-06 27.8 0.8 1.8 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 CDJ43405.1 - 0.00016 21.1 0.1 0.00031 20.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial TniB protein ORC4_C PF14629.6 CDJ43405.1 - 0.012 15.0 0.0 0.032 13.6 0.0 1.7 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus DUF3446 PF11928.8 CDJ43405.1 - 0.023 15.0 3.4 0.023 15.0 3.4 3.5 3 0 0 3 3 3 0 Early growth response N-terminal domain T2SSE PF00437.20 CDJ43405.1 - 0.029 13.4 0.1 0.061 12.4 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 CDJ43405.1 - 0.048 13.6 5.9 0.093 12.6 5.9 1.5 1 0 0 1 1 1 0 NACHT domain YchF-GTPase_C PF06071.13 CDJ43406.1 - 3.3e-41 139.4 0.7 8.9e-41 138.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CDJ43406.1 - 7e-21 74.4 0.0 4.3e-20 71.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ43406.1 - 2.1e-06 27.4 0.0 8.5e-06 25.4 0.0 2.0 3 0 0 3 3 3 1 Ferrous iron transport protein B PEP-utilisers_N PF05524.13 CDJ43406.1 - 0.043 14.0 0.5 0.11 12.7 0.5 1.6 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal TGS PF02824.21 CDJ43406.1 - 0.071 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 TGS domain AAA_18 PF13238.6 CDJ43406.1 - 0.18 12.4 0.7 45 4.6 0.0 3.0 3 1 1 4 4 4 0 AAA domain Pkinase PF00069.25 CDJ43407.1 - 4.5e-75 252.4 0.0 7.3e-75 251.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ43407.1 - 8.2e-39 133.4 0.0 1.6e-38 132.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ43407.1 - 4.8e-06 26.1 0.0 9.4e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ43407.1 - 8.7e-05 22.6 0.1 8.7e-05 22.6 0.1 3.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ43407.1 - 0.00029 20.2 0.6 0.00066 19.1 0.6 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ43407.1 - 0.00085 18.4 0.4 0.0017 17.4 0.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CDJ43407.1 - 0.068 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase GldM_N PF12081.8 CDJ43408.1 - 0.03 14.4 1.5 0.054 13.6 1.5 1.3 1 0 0 1 1 1 0 GldM N-terminal domain Spc7 PF08317.11 CDJ43408.1 - 0.045 12.6 3.3 0.082 11.8 3.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 CDJ43408.1 - 0.2 11.7 3.5 0.35 10.9 3.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 CDJ43408.1 - 0.5 8.2 2.0 0.66 7.8 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 CDJ43408.1 - 0.6 10.6 10.1 0.41 11.2 7.9 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 CDJ43409.1 - 0.028 14.6 0.5 0.028 14.6 0.5 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4423 PF14394.6 CDJ43409.1 - 0.26 11.0 10.2 0.055 13.2 3.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4423) TSC22 PF01166.18 CDJ43409.1 - 0.54 10.6 8.3 0.043 14.1 1.5 2.6 2 1 1 3 3 3 0 TSC-22/dip/bun family CbiG_C PF01890.16 CDJ43409.1 - 1.6 9.4 8.6 0.17 12.5 3.4 2.1 3 0 0 3 3 3 0 Cobalamin synthesis G C-terminus Ntox25 PF15530.6 CDJ43410.1 - 0.022 14.9 0.6 0.059 13.5 0.6 1.7 1 1 0 1 1 1 0 Bacterial toxin 25 Topoisom_bac PF01131.20 CDJ43411.1 - 6.7e-06 25.4 0.1 0.029 13.4 0.0 2.1 1 1 1 2 2 2 2 DNA topoisomerase Pkinase PF00069.25 CDJ43412.1 - 3.7e-33 115.0 0.0 5.2e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ43412.1 - 1.5e-15 57.2 0.0 2.4e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 CDJ43412.1 - 6.3e-12 45.8 0.5 6.1e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ43412.1 - 4.2e-08 32.5 1.3 0.0019 18.0 0.2 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDJ43412.1 - 4.5e-08 32.1 1.0 0.0024 17.3 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CDJ43412.1 - 2.8e-07 30.3 0.9 3.2e-05 23.7 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ43412.1 - 5.4e-07 28.8 4.3 0.0014 18.0 0.6 3.0 3 0 0 3 3 3 2 EF hand Kinase-like PF14531.6 CDJ43412.1 - 0.0002 20.8 0.0 0.00033 20.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Dockerin_1 PF00404.18 CDJ43412.1 - 0.18 12.0 1.4 2.3 8.5 1.2 2.4 1 1 1 2 2 2 0 Dockerin type I domain Dcc1 PF09724.9 CDJ43414.1 - 5.1e-13 49.0 0.1 4.7e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Sister chromatid cohesion protein Dcc1 DUF4585 PF15232.6 CDJ43414.1 - 0.12 12.4 0.0 0.42 10.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) FAD_binding_3 PF01494.19 CDJ43415.1 - 9.5e-60 202.7 2.9 1.3e-30 106.8 0.6 3.7 4 0 0 4 4 4 3 FAD binding domain Lycopene_cycl PF05834.12 CDJ43415.1 - 7.3e-05 22.0 0.1 0.00015 21.0 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 CDJ43415.1 - 0.00017 20.8 0.2 0.00017 20.8 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CDJ43415.1 - 0.00032 20.4 0.3 0.0014 18.3 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDJ43415.1 - 0.00056 19.2 0.0 0.00096 18.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDJ43415.1 - 0.0016 18.6 0.8 0.0045 17.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CDJ43415.1 - 0.0029 16.9 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ43415.1 - 0.0033 16.7 0.2 0.006 15.8 0.2 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 CDJ43415.1 - 0.0092 14.7 0.1 0.016 13.9 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein ThiF PF00899.21 CDJ43415.1 - 0.071 12.4 0.3 7.2 5.9 0.0 2.4 2 0 0 2 2 2 0 ThiF family SLATT_1 PF18181.1 CDJ43415.1 - 2.2 8.2 6.0 0.36 10.7 1.3 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Presenilin PF01080.17 CDJ43415.1 - 6.7 5.4 8.5 14 4.3 8.5 1.4 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 CDJ43416.1 - 2.8e-20 72.8 0.0 1.2e-10 41.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ43416.1 - 1e-06 28.3 0.0 0.0083 15.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pro_dh PF01619.18 CDJ43417.1 - 2.3e-64 217.8 0.0 1.3e-63 215.4 0.0 1.9 1 1 0 1 1 1 1 Proline dehydrogenase Abhydrolase_1 PF00561.20 CDJ43418.1 - 0.0017 18.0 0.1 0.029 14.0 0.1 2.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF818 PF05677.12 CDJ43418.1 - 0.0086 15.1 0.1 0.15 11.0 0.0 2.3 2 0 0 2 2 2 1 Chlamydia CHLPS protein (DUF818) PP2C PF00481.21 CDJ43419.1 - 2.1e-24 86.5 1.9 7.2e-11 42.2 0.0 3.3 3 1 0 3 3 3 2 Protein phosphatase 2C Cwf_Cwc_15 PF04889.12 CDJ43419.1 - 3.5 7.3 37.1 7.4 6.2 2.6 4.6 4 0 0 4 4 4 0 Cwf15/Cwc15 cell cycle control protein RR_TM4-6 PF06459.12 CDJ43419.1 - 9.6 5.9 44.2 0.39 10.5 16.8 4.3 4 0 0 4 4 4 0 Ryanodine Receptor TM 4-6 Ribosomal_60s PF00428.19 CDJ43422.1 - 3.3e-22 78.9 11.0 4e-22 78.6 11.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Totivirus_coat PF05518.11 CDJ43422.1 - 0.049 11.7 2.5 0.054 11.5 2.5 1.0 1 0 0 1 1 1 0 Totivirus coat protein MarR_2 PF12802.7 CDJ43423.1 - 0.012 15.5 0.2 0.034 14.0 0.2 1.8 1 0 0 1 1 1 0 MarR family Mor PF08765.11 CDJ43423.1 - 0.73 9.9 0.0 0.73 9.9 0.0 2.5 3 0 0 3 3 3 0 Mor transcription activator family SR-25 PF10500.9 CDJ43423.1 - 4 7.0 9.5 9.1 5.8 9.5 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TAF4 PF05236.14 CDJ43424.1 - 0.013 15.3 5.4 0.017 14.9 5.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Use1 PF09753.9 CDJ43424.1 - 0.4 10.4 4.2 0.53 10.0 4.2 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF5600 PF18150.1 CDJ43425.1 - 1e-38 132.2 0.1 2.3e-38 131.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 CDJ43425.1 - 4.5e-14 52.9 0.0 2.4e-13 50.5 0.0 2.0 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 CDJ43425.1 - 7.3e-14 51.4 1.1 1.4e-13 50.5 1.1 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein EF-hand_4 PF12763.7 CDJ43425.1 - 2.2e-08 34.0 0.0 4.9e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.23 CDJ43425.1 - 2.5e-07 30.8 0.0 4.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ43425.1 - 3.5e-05 23.4 0.0 0.00025 20.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 CDJ43425.1 - 0.00072 19.8 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CDJ43425.1 - 0.0082 16.1 0.0 0.59 10.0 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase SUIM_assoc PF16619.5 CDJ43425.1 - 0.0088 16.1 0.1 0.021 14.9 0.1 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 AAA_28 PF13521.6 CDJ43425.1 - 0.023 15.0 0.0 0.067 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CDJ43425.1 - 0.054 13.2 0.0 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation EF-hand_7 PF13499.6 CDJ43425.1 - 0.066 13.7 0.0 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair AAA_16 PF13191.6 CDJ43425.1 - 0.15 12.4 0.0 0.99 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 CDJ43425.1 - 0.18 11.9 0.2 3 8.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain Mem_trans PF03547.18 CDJ43426.1 - 0.71 8.2 3.1 0.65 8.3 2.0 1.5 1 1 0 1 1 1 0 Membrane transport protein Spore_III_AF PF09581.10 CDJ43426.1 - 9 6.3 14.1 1.2 9.1 4.6 2.9 2 1 1 3 3 3 0 Stage III sporulation protein AF (Spore_III_AF) GatB_N PF02934.15 CDJ43427.1 - 3e-73 246.6 0.0 3.4e-70 236.5 0.0 2.8 2 1 0 2 2 2 1 GatB/GatE catalytic domain LysE PF01810.18 CDJ43428.1 - 0.071 12.6 0.3 0.15 11.5 0.3 1.4 1 0 0 1 1 1 0 LysE type translocator DLIC PF05783.11 CDJ43428.1 - 0.23 10.2 5.8 0.41 9.4 5.8 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) PAP1 PF08601.10 CDJ43430.1 - 0.0083 15.9 15.1 0.0098 15.7 15.1 1.0 1 0 0 1 1 1 1 Transcription factor PAP1 DUF755 PF05501.11 CDJ43430.1 - 0.041 14.1 18.6 0.058 13.7 18.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) ANAPC_CDC26 PF10471.9 CDJ43430.1 - 0.047 14.5 6.5 0.084 13.7 6.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 SDP_N PF12278.8 CDJ43430.1 - 0.079 13.1 2.8 0.1 12.7 2.8 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal DUF1635 PF07795.11 CDJ43430.1 - 0.42 10.4 11.4 0.84 9.4 11.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) GREB1 PF15782.5 CDJ43430.1 - 0.47 7.5 7.0 0.48 7.5 7.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CNDH2_M PF16869.5 CDJ43430.1 - 0.73 10.5 4.4 1.1 9.9 4.4 1.3 1 0 0 1 1 1 0 PF16858 FAM199X PF15814.5 CDJ43430.1 - 0.88 8.6 12.6 1 8.4 12.6 1.1 1 0 0 1 1 1 0 Protein family FAM199X Spt20 PF12090.8 CDJ43430.1 - 0.9 9.1 7.8 1.1 8.8 7.8 1.1 1 0 0 1 1 1 0 Spt20 family Apt1 PF10351.9 CDJ43430.1 - 1.4 7.7 5.8 1.5 7.6 5.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAM-associated PF14303.6 CDJ43430.1 - 1.5 9.5 7.1 1.8 9.2 7.1 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain HSD3 PF15244.6 CDJ43430.1 - 1.6 8.2 10.2 1.9 7.9 10.2 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 TFIIA PF03153.13 CDJ43430.1 - 2 8.3 8.2 2.3 8.1 8.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 CDJ43430.1 - 3.2 5.7 17.6 3.8 5.5 17.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 CDJ43430.1 - 4.7 5.6 8.6 5.7 5.4 8.6 1.1 1 0 0 1 1 1 0 Macoilin family Peroxin-3 PF04882.12 CDJ43430.1 - 7.6 5.4 10.8 9.6 5.1 10.8 1.1 1 0 0 1 1 1 0 Peroxin-3 tRNA-synt_1b PF00579.25 CDJ43432.1 - 6.5e-26 91.3 0.0 4.7e-24 85.2 0.0 3.0 1 1 1 2 2 2 1 tRNA synthetases class I (W and Y) S4 PF01479.25 CDJ43432.1 - 8.9e-05 22.1 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain NUDIX PF00293.28 CDJ43433.1 - 3.7e-20 72.3 0.0 7.2e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SR-25 PF10500.9 CDJ43433.1 - 7.5e-06 25.7 8.0 7.5e-06 25.7 8.0 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ43433.1 - 0.00028 21.3 10.8 0.0041 17.4 2.1 3.0 2 1 1 3 3 3 3 Anti-sigma-K factor rskA DUF755 PF05501.11 CDJ43433.1 - 0.0088 16.3 4.1 0.0088 16.3 4.1 4.3 3 1 1 4 4 2 1 Domain of unknown function (DUF755) MecA PF05389.12 CDJ43433.1 - 0.028 14.0 0.4 0.028 14.0 0.4 3.1 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) BRF1 PF07741.13 CDJ43433.1 - 0.03 14.7 0.5 0.03 14.7 0.5 3.3 3 0 0 3 3 3 0 Brf1-like TBP-binding domain TCP PF03634.13 CDJ43433.1 - 0.05 14.2 23.9 0.74 10.4 0.3 3.1 3 0 0 3 3 3 0 TCP family transcription factor Peroxin-13_N PF04088.13 CDJ43433.1 - 0.21 11.9 11.8 0.6 10.4 0.9 3.3 3 0 0 3 3 3 0 Peroxin 13, N-terminal region SLC12 PF03522.15 CDJ43433.1 - 0.43 9.5 22.9 0.18 10.8 17.7 2.0 2 0 0 2 2 2 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ43433.1 - 0.69 9.7 22.4 0.93 9.3 3.9 3.0 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 MAP17 PF15807.5 CDJ43433.1 - 0.81 9.9 11.1 2.1 8.6 0.3 3.1 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RIC3 PF15361.6 CDJ43433.1 - 1.6 9.2 17.5 1.3 9.4 1.1 3.1 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 SpoIIP PF07454.11 CDJ43433.1 - 1.8 8.0 21.4 0.79 9.1 3.0 3.1 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) EIIBC-GUT_N PF03612.14 CDJ43433.1 - 2.8 7.6 20.0 1.7 8.3 4.5 3.2 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus Inhibitor_I71 PF12628.7 CDJ43434.1 - 0.051 13.4 0.1 0.071 13.0 0.1 1.2 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor HMG_box PF00505.19 CDJ43436.1 - 1.4e-19 70.3 2.8 2.1e-19 69.7 2.8 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ43436.1 - 4.4e-11 43.2 3.0 6.4e-11 42.7 3.0 1.3 1 0 0 1 1 1 1 HMG-box domain DUF5566 PF17721.1 CDJ43436.1 - 0.0038 17.5 9.7 0.0043 17.4 9.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5566) MlaC PF05494.12 CDJ43436.1 - 0.0096 15.7 1.5 0.013 15.3 1.5 1.2 1 0 0 1 1 1 1 MlaC protein YABBY PF04690.13 CDJ43436.1 - 0.014 16.0 1.1 0.014 16.0 1.1 1.5 1 1 0 1 1 1 0 YABBY protein DUF508 PF04370.12 CDJ43436.1 - 0.15 11.8 5.7 0.21 11.3 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Sporozoite_P67 PF05642.11 CDJ43436.1 - 0.26 9.3 6.3 0.28 9.2 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GET2 PF08690.10 CDJ43436.1 - 0.61 9.7 7.7 0.65 9.6 7.7 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 RAP1 PF07218.11 CDJ43436.1 - 3 6.0 9.8 3 6.0 9.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apc15p PF05841.11 CDJ43436.1 - 7.1 7.5 10.9 2.4 9.0 0.2 2.2 1 1 1 2 2 2 0 Apc15p protein Longin PF13774.6 CDJ43437.1 - 7.1e-13 48.4 0.0 1.5e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CDJ43437.1 - 3.1e-05 23.7 4.2 3.1e-05 23.7 4.2 1.8 2 0 0 2 2 2 1 Synaptobrevin DUF2284 PF10050.9 CDJ43437.1 - 0.0025 17.6 0.0 0.0036 17.1 0.0 1.2 1 0 0 1 1 1 1 Predicted metal-binding protein (DUF2284) MCM PF00493.23 CDJ43438.1 - 3.7e-89 297.7 0.0 1e-88 296.2 0.0 1.8 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CDJ43438.1 - 1.3e-22 80.0 1.7 3.7e-22 78.6 1.7 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDJ43438.1 - 1.4e-07 31.1 0.0 8.4e-06 25.3 0.1 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDJ43438.1 - 1.2e-06 28.6 0.0 3.1e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDJ43438.1 - 0.00011 22.1 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ43438.1 - 0.00023 20.9 0.0 0.32 10.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain GntR PF00392.21 CDJ43438.1 - 0.036 13.7 0.0 0.09 12.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Tryp_alpha_amyl PF00234.22 CDJ43438.1 - 0.16 12.4 3.7 0.44 11.0 0.1 3.0 3 0 0 3 3 3 0 Protease inhibitor/seed storage/LTP family RskA PF10099.9 CDJ43439.1 - 6.1e-05 23.4 8.1 0.23 11.7 0.0 2.3 1 1 1 2 2 2 2 Anti-sigma-K factor rskA Dev_Cell_Death PF10539.9 CDJ43439.1 - 0.061 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Development and cell death domain SUIM_assoc PF16619.5 CDJ43439.1 - 0.1 12.7 0.0 0.1 12.7 0.0 3.8 3 1 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Abhydrolase_9_N PF15420.6 CDJ43439.1 - 0.96 9.4 8.4 20 5.1 9.4 2.2 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus DLIC PF05783.11 CDJ43439.1 - 1.8 7.3 4.4 2.4 6.9 4.4 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Paf67 PF10255.9 CDJ43440.1 - 1.4e-130 436.0 0.2 1.8e-130 435.6 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 CDJ43440.1 - 0.0023 17.9 0.0 0.0082 16.2 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Pro_isomerase PF00160.21 CDJ43441.1 - 1.1e-14 55.0 0.0 1.6e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Gluconate_2-dh3 PF13618.6 CDJ43441.1 - 0.11 12.7 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 TFIIA PF03153.13 CDJ43442.1 - 0.0027 17.8 6.8 0.0034 17.5 6.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ43442.1 - 0.027 14.1 1.6 0.043 13.4 1.6 1.3 1 0 0 1 1 1 0 Spt20 family PQ-loop PF04193.14 CDJ43442.1 - 0.032 14.0 0.4 0.072 12.9 0.0 1.7 2 0 0 2 2 2 0 PQ loop repeat Ribosomal_60s PF00428.19 CDJ43442.1 - 0.043 14.4 10.8 0.043 14.4 10.8 3.8 2 1 0 2 2 2 0 60s Acidic ribosomal protein Dehydrin PF00257.19 CDJ43442.1 - 0.46 11.0 10.6 0.38 11.3 7.4 2.0 2 0 0 2 2 2 0 Dehydrin EIF_2_alpha PF07541.12 CDJ43443.1 - 1.7e-29 102.3 0.3 1.7e-29 102.3 0.3 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CDJ43443.1 - 6.3e-12 45.7 0.2 6.3e-12 45.7 0.2 1.7 2 0 0 2 2 2 1 S1 RNA binding domain Nucleo_P87 PF07267.11 CDJ43443.1 - 0.078 11.8 1.5 0.11 11.3 1.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CPP1-like PF11833.8 CDJ43443.1 - 0.12 12.0 0.5 0.22 11.1 0.5 1.4 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Phage_1_1 PF08200.11 CDJ43443.1 - 0.16 12.4 0.1 0.42 11.1 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein EXOSC1 PF10447.9 CDJ43443.1 - 0.17 12.5 1.4 0.28 11.8 0.3 2.0 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 TSP_1 PF00090.19 CDJ43444.1 - 1.3e-05 25.3 19.3 0.0015 18.7 0.8 5.3 4 0 0 4 4 4 2 Thrombospondin type 1 domain TSP_1 PF00090.19 CDJ43445.1 - 0.0016 18.6 8.5 0.0016 18.6 8.5 2.5 2 1 0 2 2 2 1 Thrombospondin type 1 domain Septin PF00735.18 CDJ43445.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.5 2 0 0 2 2 2 0 Septin H_lectin PF09458.10 CDJ43446.1 - 0.13 12.5 0.3 0.48 10.6 0.0 2.3 2 0 0 2 2 2 0 H-type lectin domain DUF1201 PF06716.11 CDJ43448.1 - 0.092 12.8 1.1 0.16 12.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) Aconitase PF00330.20 CDJ43449.1 - 3.6e-169 563.6 0.0 4.6e-169 563.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CDJ43449.1 - 1.3e-41 142.0 0.0 2.6e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Nsp1_C PF05064.13 CDJ43450.1 - 9.6e-13 48.0 3.4 9.6e-13 48.0 3.4 2.0 1 1 2 3 3 3 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 CDJ43450.1 - 7.6e-11 42.7 145.8 0.0013 19.5 35.3 7.5 1 1 6 7 7 7 5 Nucleoporin FG repeat region DUF1664 PF07889.12 CDJ43450.1 - 0.44 10.6 9.1 3.2 7.8 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 CDJ43451.1 - 3.1e-32 112.0 0.0 3.9e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ43451.1 - 2.3e-23 82.8 0.0 2.9e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ43451.1 - 1.8e-10 40.2 0.0 2.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ43451.1 - 0.0012 18.9 0.0 0.03 14.2 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.16 CDJ43451.1 - 0.026 14.7 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Pox_ser-thr_kin PF05445.11 CDJ43451.1 - 0.062 12.3 0.1 0.095 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TRAM_LAG1_CLN8 PF03798.16 CDJ43453.1 - 3.1e-27 95.6 19.2 4.1e-27 95.2 19.2 1.2 1 0 0 1 1 1 1 TLC domain CHD5 PF04420.14 CDJ43454.1 - 0.13 12.1 0.4 0.22 11.3 0.4 1.3 1 0 0 1 1 1 0 CHD5-like protein Dynamin_M PF01031.20 CDJ43455.1 - 4.8e-86 288.5 0.0 2.8e-84 282.7 0.0 2.3 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CDJ43455.1 - 9.9e-53 178.6 0.0 2.2e-52 177.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CDJ43455.1 - 4.4e-30 103.7 2.5 6.6e-30 103.1 1.2 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CDJ43455.1 - 6.2e-06 26.3 0.0 1.6e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CDJ43455.1 - 0.0042 17.5 0.6 0.65 10.4 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain T3SS_needle_E PF08988.10 CDJ43455.1 - 0.37 11.0 2.5 20 5.4 0.0 3.0 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Amino_oxidase PF01593.24 CDJ43456.1 - 3.6e-42 145.2 2.9 2.6e-33 116.0 0.1 2.8 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase zf-CW PF07496.15 CDJ43456.1 - 2.9e-37 126.5 40.2 1.1e-12 47.8 5.6 3.6 3 0 0 3 3 3 3 CW-type Zinc Finger NAD_binding_8 PF13450.6 CDJ43456.1 - 1e-05 25.6 4.1 1e-05 25.6 4.1 3.5 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ43456.1 - 0.0018 17.5 0.2 0.0037 16.5 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ43456.1 - 0.012 14.9 1.6 0.024 13.9 1.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ43456.1 - 0.017 13.8 0.3 0.017 13.8 0.3 3.5 4 0 0 4 4 4 0 HI0933-like protein Thi4 PF01946.17 CDJ43456.1 - 0.042 13.1 0.2 0.087 12.1 0.2 1.4 1 0 0 1 1 1 0 Thi4 family PHD PF00628.29 CDJ43456.1 - 0.76 9.7 12.2 8.9 6.3 0.8 4.2 3 1 0 3 3 3 0 PHD-finger DAO PF01266.24 CDJ43456.1 - 2.7 7.5 19.0 0.025 14.2 3.3 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thioredoxin PF00085.20 CDJ43457.1 - 8.2e-138 449.8 0.7 3.6e-21 75.1 0.0 7.3 7 0 0 7 7 7 7 Thioredoxin Glyco_transf_90 PF05686.12 CDJ43457.1 - 5.6e-58 196.7 0.0 8.3e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Thioredoxin_2 PF13098.6 CDJ43457.1 - 6.9e-35 119.8 0.0 0.0015 19.0 0.0 7.3 6 0 0 6 6 6 6 Thioredoxin-like domain OST3_OST6 PF04756.13 CDJ43457.1 - 3.1e-28 99.0 2.3 0.0012 18.3 0.0 7.2 8 0 0 8 8 8 5 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CDJ43457.1 - 7.9e-27 93.3 0.0 0.037 14.2 0.0 6.8 6 0 0 6 6 6 6 Thioredoxin-like ERp29_N PF07912.13 CDJ43457.1 - 1.1e-20 74.1 0.7 0.071 13.3 0.0 6.2 6 0 0 6 6 6 5 ERp29, N-terminal domain Thioredoxin_6 PF13848.6 CDJ43457.1 - 6e-18 65.4 2.8 0.16 11.8 0.0 6.3 6 0 0 6 6 6 5 Thioredoxin-like domain TraF PF13728.6 CDJ43457.1 - 2.6e-13 50.4 0.0 4.7 7.0 0.0 7.6 2 1 8 10 10 10 5 F plasmid transfer operon protein AhpC-TSA PF00578.21 CDJ43457.1 - 1e-11 44.8 1.2 13 5.7 0.0 7.4 7 0 0 7 7 7 0 AhpC/TSA family Thioredoxin_8 PF13905.6 CDJ43457.1 - 1.7e-11 44.3 2.3 16 5.9 0.0 8.6 7 5 0 7 7 7 0 Thioredoxin-like Redoxin PF08534.10 CDJ43457.1 - 3.4e-10 39.8 6.9 3.2 7.4 0.0 7.1 7 0 0 7 7 7 4 Redoxin Glutaredoxin PF00462.24 CDJ43457.1 - 4.1e-08 33.3 3.1 2 8.7 0.0 7.4 7 0 0 7 7 7 1 Glutaredoxin Thioredoxin_9 PF14595.6 CDJ43457.1 - 3.3e-07 30.1 0.0 4.1 7.2 0.0 6.9 7 0 0 7 7 7 1 Thioredoxin MAAL_C PF07476.11 CDJ43457.1 - 4.5e-07 29.3 3.0 3.8 6.6 0.0 4.3 4 0 0 4 4 4 4 Methylaspartate ammonia-lyase C-terminus ProRS-C_1 PF09180.11 CDJ43457.1 - 7.8e-07 29.2 2.8 39 4.6 0.0 6.4 6 0 0 6 6 6 0 Prolyl-tRNA synthetase, C-terminal CdvA PF18822.1 CDJ43457.1 - 0.00019 21.2 0.9 97 2.8 0.0 5.0 5 0 0 5 5 5 0 CdvA-like coiled-coil domain Glyco_trans_1_2 PF13524.6 CDJ43457.1 - 0.00032 21.0 0.0 0.00074 19.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Phytase PF02333.15 CDJ43457.1 - 0.00044 19.3 3.5 17 4.2 0.0 4.1 4 0 0 4 4 4 0 Phytase ACP PF06857.11 CDJ43457.1 - 0.0023 18.1 0.3 1.3e+02 2.9 0.0 4.5 4 0 0 4 4 4 0 Malonate decarboxylase delta subunit (MdcD) DUF4549 PF15082.6 CDJ43457.1 - 0.0049 16.7 0.0 1.8e+02 1.9 0.0 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4549) HET-s_218-289 PF11558.8 CDJ43457.1 - 0.0099 15.9 0.7 1.5e+02 2.4 0.0 4.4 4 0 0 4 4 4 0 Het-s 218-289 Filamin PF00630.19 CDJ43457.1 - 0.059 14.2 0.0 0.15 12.9 0.0 1.6 1 0 0 1 1 1 0 Filamin/ABP280 repeat Band_7_C PF16200.5 CDJ43457.1 - 0.38 10.9 3.1 4.6e+02 1.0 0.0 4.8 5 0 0 5 5 5 0 C-terminal region of band_7 DUF2280 PF10045.9 CDJ43458.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) Coa1 PF08695.10 CDJ43458.1 - 0.14 11.9 0.0 0.57 9.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome oxidase complex assembly protein 1 EF-hand_1 PF00036.32 CDJ43459.1 - 1.3e-27 93.2 4.3 1.9e-07 30.1 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CDJ43459.1 - 1.7e-24 84.2 3.7 5.6e-07 28.8 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ43459.1 - 4.2e-24 84.8 2.3 2.8e-12 46.9 0.5 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ43459.1 - 1e-20 71.8 3.4 0.00094 18.9 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDJ43459.1 - 5.7e-13 48.5 7.0 3.7e-05 23.5 1.4 4.6 4 1 1 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ43459.1 - 1.2e-09 38.5 0.0 0.00023 21.4 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDJ43459.1 - 2.4e-05 24.2 1.9 0.19 11.7 0.3 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CDJ43459.1 - 0.00018 21.6 4.6 0.0086 16.2 0.1 3.8 2 1 2 4 4 4 3 Dockerin type I domain EF-hand_9 PF14658.6 CDJ43459.1 - 0.00079 19.7 0.0 0.048 14.0 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain NOD2_WH PF17779.1 CDJ43459.1 - 0.031 14.6 0.1 1.6 9.1 0.0 2.7 3 0 0 3 3 3 0 NOD2 winged helix domain Caleosin PF05042.13 CDJ43459.1 - 0.044 13.7 1.1 4.6 7.2 0.0 3.2 2 1 2 4 4 4 0 Caleosin related protein PUB PF09409.10 CDJ43460.1 - 2e-05 24.4 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 PUB domain CCDC53 PF10152.9 CDJ43460.1 - 4.3 7.7 6.7 16 5.9 6.7 2.0 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Asp PF00026.23 CDJ43461.1 - 2.6e-18 66.5 0.0 9.9e-18 64.6 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Mito_carr PF00153.27 CDJ43462.1 - 8.6e-39 131.4 1.5 1.3e-18 66.7 0.3 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Fer4_11 PF13247.6 CDJ43464.1 - 0.047 13.8 0.3 0.3 11.2 0.1 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Abhydrolase_1 PF00561.20 CDJ43466.1 - 0.061 13.0 0.0 0.061 13.0 0.0 2.8 3 0 0 3 3 3 0 alpha/beta hydrolase fold Peptidase_S10 PF00450.22 CDJ43466.1 - 0.097 12.1 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 Serine carboxypeptidase CLN3 PF02487.17 CDJ43466.1 - 0.23 10.4 4.1 4.2 6.3 0.2 3.2 3 0 0 3 3 3 0 CLN3 protein Acetyltransf_1 PF00583.25 CDJ43467.1 - 8.8e-11 42.1 0.0 1.3e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ43467.1 - 2.5e-05 24.2 0.1 4.1e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ43467.1 - 8.9e-05 22.9 0.1 0.00013 22.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ43467.1 - 0.00021 21.2 0.1 0.00039 20.3 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CDJ43467.1 - 0.0017 18.4 0.1 0.003 17.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Dehydrin PF00257.19 CDJ43467.1 - 0.055 14.0 11.0 0.097 13.2 11.0 1.4 1 0 0 1 1 1 0 Dehydrin Oscp1 PF10188.9 CDJ43467.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Organic solute transport protein 1 SR-25 PF10500.9 CDJ43467.1 - 0.42 10.2 22.9 0.69 9.5 22.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 CDJ43467.1 - 0.47 10.0 8.4 0.62 9.6 8.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RIFIN PF02009.16 CDJ43467.1 - 0.58 10.0 5.1 0.69 9.8 5.1 1.2 1 0 0 1 1 1 0 Rifin Macoilin PF09726.9 CDJ43467.1 - 0.65 8.5 12.5 0.73 8.3 12.5 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_M24 PF00557.24 CDJ43469.1 - 5.6e-15 55.6 0.2 5.2e-09 36.1 0.0 2.4 1 1 1 2 2 2 2 Metallopeptidase family M24 Med3 PF11593.8 CDJ43469.1 - 6.4 5.9 8.8 10 5.2 8.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Aa_trans PF01490.18 CDJ43470.1 - 1.3e-06 27.4 5.5 1.3e-06 27.4 5.5 2.2 3 0 0 3 3 3 1 Transmembrane amino acid transporter protein Macoilin PF09726.9 CDJ43470.1 - 0.25 9.9 11.3 0.37 9.3 11.3 1.2 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 CDJ43470.1 - 0.44 10.4 14.6 0.83 9.5 14.6 1.4 1 0 0 1 1 1 0 SPX domain TFIIA PF03153.13 CDJ43470.1 - 0.45 10.5 7.8 0.67 9.9 7.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 CDJ43470.1 - 2.1 6.3 5.5 3.1 5.8 5.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Apt1 PF10351.9 CDJ43470.1 - 3 6.6 14.6 4.3 6.1 14.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 CDJ43470.1 - 3.7 4.5 12.3 3.5 4.6 10.9 1.6 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 CDJ43470.1 - 4.1 6.5 18.7 7.2 5.7 18.7 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein GATase PF00117.28 CDJ43471.1 - 4.3e-50 170.1 0.2 1.3e-49 168.6 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CDJ43471.1 - 1.9e-05 24.5 3.2 3.4e-05 23.7 0.0 2.8 2 0 0 2 2 2 1 Peptidase C26 Neur_chan_memb PF02932.16 CDJ43471.1 - 1.3 9.0 17.0 1.5 8.8 2.2 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region GDA1_CD39 PF01150.17 CDJ43472.1 - 3.9e-12 45.6 0.0 2.6e-11 42.9 0.0 2.3 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family TFIIA PF03153.13 CDJ43472.1 - 0.00035 20.7 44.6 0.052 13.5 13.5 2.4 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ43472.1 - 3.3 7.8 14.7 5.4 7.1 3.3 2.5 2 0 0 2 2 2 0 DDHD domain Velvet PF11754.8 CDJ43472.1 - 3.8 7.4 21.0 2.7 7.9 4.9 2.4 2 0 0 2 2 2 0 Velvet factor MMR1 PF08505.10 CDJ43472.1 - 4 7.6 27.5 3.3 7.9 8.7 2.4 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein CRAL_TRIO PF00650.20 CDJ43473.1 - 1.2e-11 44.6 0.0 1.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Ndc1_Nup PF09531.10 CDJ43473.1 - 0.012 14.3 3.4 0.014 14.1 3.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ43473.1 - 0.019 13.8 4.1 0.023 13.5 4.1 1.1 1 0 0 1 1 1 0 Presenilin DUF3402 PF11882.8 CDJ43473.1 - 0.02 14.0 6.9 0.036 13.2 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Pex14_N PF04695.13 CDJ43473.1 - 0.081 13.6 23.3 0.12 13.0 23.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 CDJ43473.1 - 0.64 8.2 20.9 0.79 7.9 20.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PepSY_TM PF03929.16 CDJ43473.1 - 0.77 9.4 2.7 1.1 8.9 2.7 1.3 1 0 0 1 1 1 0 PepSY-associated TM region CCDC53 PF10152.9 CDJ43473.1 - 1.9 8.9 16.6 3.1 8.2 16.6 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2076 PF09849.9 CDJ43473.1 - 2 8.4 30.2 3 7.8 30.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Suf PF05843.14 CDJ43473.1 - 4.4 7.2 16.3 6.3 6.7 16.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ43473.1 - 5.4 6.9 34.9 7.3 6.5 34.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ43473.1 - 5.4 5.9 10.3 7.6 5.4 10.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1206 PF06724.11 CDJ43474.1 - 0.0041 17.2 2.4 0.017 15.2 0.1 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1206) ABC_membrane PF00664.23 CDJ43474.1 - 0.034 13.8 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region Zip PF02535.22 CDJ43474.1 - 0.055 12.7 3.4 0.08 12.1 3.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.9 CDJ43474.1 - 0.38 9.3 11.2 0.5 8.9 11.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF1180 PF06679.12 CDJ43474.1 - 0.57 10.6 2.9 1.5 9.2 2.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) NicO PF03824.16 CDJ43474.1 - 1 8.7 4.0 9 5.5 3.5 2.0 2 0 0 2 2 2 0 High-affinity nickel-transport protein Melibiase_C PF17801.1 CDJ43475.1 - 5.1e-05 23.3 0.0 6.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 CDJ43475.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain SNF2_N PF00176.23 CDJ43476.1 - 5.4e-42 143.7 0.0 4.5e-33 114.4 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ43476.1 - 7.9e-18 64.8 0.0 1.8e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ43476.1 - 5.1e-08 33.1 0.0 1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ43476.1 - 0.00011 22.0 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CDJ43476.1 - 0.0021 17.3 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Nop25 PF09805.9 CDJ43476.1 - 0.27 11.7 6.0 1.4 9.4 6.0 2.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) PNTB PF02233.16 CDJ43479.1 - 1.6e-154 515.3 22.2 1.2e-128 429.9 8.3 2.6 1 1 1 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 CDJ43479.1 - 4.1e-66 222.4 0.3 7e-66 221.6 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 CDJ43479.1 - 5.1e-18 65.7 0.0 1.2e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 CDJ43479.1 - 3e-11 43.6 5.5 3e-11 43.6 5.5 3.5 3 0 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 CDJ43479.1 - 7.3e-06 25.5 0.1 0.059 12.7 0.2 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 CDJ43479.1 - 0.0049 16.6 0.4 0.081 12.7 0.1 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Tti2 PF10521.9 CDJ43480.1 - 0.0017 18.0 0.5 0.055 13.0 0.0 2.8 3 0 0 3 3 3 2 Tti2 family AAA_11 PF13086.6 CDJ43481.1 - 1.9e-56 191.8 0.1 7.5e-29 101.3 0.9 3.3 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 CDJ43481.1 - 8.8e-56 188.7 0.0 1.8e-55 187.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ43481.1 - 6.4e-11 42.3 0.1 6.9e-05 22.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDJ43481.1 - 8.4e-11 42.4 0.0 0.00053 20.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 CDJ43481.1 - 0.001 18.8 0.1 0.085 12.6 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CDJ43481.1 - 0.012 15.1 0.1 2.7 7.4 0.1 2.7 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 CDJ43481.1 - 0.093 13.1 0.4 0.62 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 CDJ43481.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvrD_C_2 PF13538.6 CDJ43481.1 - 0.17 11.8 0.0 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA PF00004.29 CDJ43481.1 - 0.19 12.2 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RRM_1 PF00076.22 CDJ43484.1 - 1.4e-37 127.3 0.2 2.4e-14 52.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CDJ43484.1 - 1.8e-06 28.9 0.4 1.8e-06 28.9 0.4 2.5 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 CDJ43484.1 - 1.4e-05 24.8 0.0 0.094 12.6 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif DUF1866 PF08952.11 CDJ43484.1 - 0.018 14.9 0.0 0.058 13.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Lipoprotein_8 PF02030.15 CDJ43484.1 - 0.035 12.8 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) RRM_3 PF08777.11 CDJ43484.1 - 0.061 13.4 0.1 11 6.1 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif DbpA PF03880.15 CDJ43484.1 - 0.35 10.9 1.2 65 3.6 0.0 3.6 4 1 0 4 4 4 0 DbpA RNA binding domain PIP5K PF01504.18 CDJ43485.1 - 4.3e-72 242.6 0.4 7.9e-72 241.8 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_1 PF00036.32 CDJ43485.1 - 8e-05 21.9 0.2 0.00035 19.9 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CDJ43485.1 - 0.0017 18.8 0.1 0.0054 17.2 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ43485.1 - 0.0069 16.2 0.0 0.028 14.3 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain LRR_8 PF13855.6 CDJ43486.1 - 1.3e-12 47.2 45.1 5.5e-07 29.3 12.8 3.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CDJ43486.1 - 2.8e-11 43.4 28.6 2.3e-05 24.7 8.2 4.1 1 1 5 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ43486.1 - 0.00097 18.7 7.8 0.0019 17.7 3.5 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LCD1 PF09798.9 CDJ43486.1 - 0.11 10.9 1.4 1.7 7.0 0.1 2.3 2 0 0 2 2 2 0 DNA damage checkpoint protein zf-CDGSH PF09360.10 CDJ43488.1 - 1.4e-10 41.2 0.2 3.8e-10 39.8 0.1 1.7 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type DUF2076 PF09849.9 CDJ43488.1 - 9.4e-05 22.6 2.0 0.00013 22.1 2.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF2309 PF10070.9 CDJ43488.1 - 0.009 14.4 0.3 0.011 14.1 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2309) SARAF PF06682.12 CDJ43488.1 - 0.014 15.1 0.4 0.018 14.7 0.4 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Trep_Strep PF09605.10 CDJ43488.1 - 0.034 14.1 0.0 0.04 13.9 0.0 1.1 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF3180 PF11377.8 CDJ43488.1 - 0.062 13.5 1.6 0.084 13.0 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) TMEM237 PF15383.6 CDJ43488.1 - 0.12 11.4 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 FxsA PF04186.13 CDJ43488.1 - 5.8 7.1 5.9 1.6 8.9 0.3 2.1 1 1 1 2 2 2 0 FxsA cytoplasmic membrane protein UBM PF14377.6 CDJ43489.1 - 5.4e-07 28.8 0.7 5.4e-07 28.8 0.7 5.0 3 1 1 4 4 4 2 Ubiquitin binding region AARP2CN PF08142.12 CDJ43490.1 - 2.1e-23 82.2 3.4 4.4e-21 74.8 3.4 2.8 1 1 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 CDJ43490.1 - 6.8e-07 29.0 3.4 3.1e-06 26.9 3.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TFIIA PF03153.13 CDJ43490.1 - 0.00053 20.1 26.6 0.00053 20.1 26.6 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ43490.1 - 0.00079 19.1 7.2 0.00079 19.1 7.2 4.2 4 1 0 4 4 3 2 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ43490.1 - 0.0032 17.7 18.3 0.0032 17.7 18.3 2.5 2 1 0 2 2 2 1 Centriole, cilia and spindle-associated Oest_recep PF02159.15 CDJ43490.1 - 0.018 15.5 3.9 0.045 14.2 0.0 2.5 2 0 0 2 2 2 0 Oestrogen receptor Coilin_N PF15862.5 CDJ43490.1 - 0.048 13.5 0.5 0.048 13.5 0.5 3.1 3 0 0 3 3 3 0 Coilin N-terminus RR_TM4-6 PF06459.12 CDJ43490.1 - 0.38 10.6 17.6 0.81 9.5 10.1 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 CDJ43490.1 - 0.5 8.4 11.7 0.8 7.7 11.7 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 CDJ43490.1 - 3.1 6.0 16.0 1.9 6.7 8.3 2.1 2 0 0 2 2 2 0 CDC45-like protein PPP4R2 PF09184.11 CDJ43490.1 - 3.9 7.0 14.1 0.34 10.4 9.4 1.7 2 0 0 2 2 2 0 PPP4R2 DUF5427 PF10310.9 CDJ43490.1 - 5.1 5.9 20.9 0.099 11.6 11.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5427) DUF719 PF05334.13 CDJ43490.1 - 9.2 6.4 12.5 5.8 7.1 5.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF719) E1_dh PF00676.20 CDJ43491.1 - 1.7e-64 217.7 0.0 2e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CDJ43491.1 - 0.12 11.5 0.0 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase DUF3810 PF12725.7 CDJ43492.1 - 0.016 14.6 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) SpoIIP PF07454.11 CDJ43492.1 - 4.1 6.8 19.2 39 3.6 12.9 3.2 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) RRM_1 PF00076.22 CDJ43493.1 - 8.2e-18 64.0 0.1 1.2e-17 63.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ43493.1 - 8.2e-05 22.7 0.0 0.00018 21.6 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ43493.1 - 0.006 16.5 0.0 0.0098 15.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CDJ43493.1 - 0.042 13.9 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif SOG2 PF10428.9 CDJ43496.1 - 0.00084 18.7 25.1 0.00088 18.6 25.1 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein HSD3 PF15244.6 CDJ43496.1 - 7.6 5.9 34.0 11 5.4 34.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Sugar_tr PF00083.24 CDJ43497.1 - 9.8e-40 136.8 16.2 2.3e-38 132.3 16.2 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter partial_CstF PF15861.5 CDJ43498.1 - 0.0024 17.6 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 Partial cleavage stimulation factor domain Ras PF00071.22 CDJ43500.1 - 0.00026 20.6 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 2 Ras family CPT PF07931.12 CDJ43500.1 - 0.024 14.5 0.0 0.085 12.7 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Roc PF08477.13 CDJ43500.1 - 0.025 14.8 0.0 0.057 13.6 0.0 1.8 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDJ43500.1 - 0.084 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein CSTF1_dimer PF16699.5 CDJ43500.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Cleavage stimulation factor subunit 1, dimerisation domain ComA PF02679.15 CDJ43501.1 - 0.088 12.3 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Med5 PF08689.10 CDJ43501.1 - 0.13 10.0 2.3 0.15 9.8 2.3 1.0 1 0 0 1 1 1 0 Mediator complex subunit Med5 FAM176 PF14851.6 CDJ43501.1 - 0.15 11.7 5.6 0.2 11.3 5.6 1.3 1 1 0 1 1 1 0 FAM176 family TFIIA PF03153.13 CDJ43501.1 - 0.25 11.3 16.0 0.3 11.0 16.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ43501.1 - 1 7.2 4.2 1.2 6.9 4.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MDFI PF15316.6 CDJ43501.1 - 1.1 9.3 4.0 1.3 9.1 4.0 1.1 1 0 0 1 1 1 0 MyoD family inhibitor A_deaminase_N PF08451.11 CDJ43501.1 - 2.4 8.5 6.9 0.35 11.2 1.7 1.8 1 1 1 2 2 2 0 Adenosine/AMP deaminase N-terminal Pkinase PF00069.25 CDJ43502.1 - 9.8e-49 166.1 0.0 1.4e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ43502.1 - 6.2e-27 94.5 0.0 9.2e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ43502.1 - 1.2e-07 31.4 0.0 6.2e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ43502.1 - 0.0039 16.6 0.1 0.0082 15.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 CDJ43502.1 - 0.14 11.7 0.6 0.33 10.6 0.6 1.6 1 1 0 1 1 1 0 Protein-kinase domain of FAM69 DGF-1_C PF11040.8 CDJ43502.1 - 0.45 10.5 0.0 0.45 10.5 0.0 3.7 3 2 1 4 4 4 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus UPF0524 PF15823.5 CDJ43503.1 - 0.0046 16.4 12.7 0.0052 16.2 12.7 1.1 1 0 0 1 1 1 1 UPF0524 of C3orf70 Spt20 PF12090.8 CDJ43503.1 - 0.013 15.1 25.7 0.015 14.9 25.7 1.1 1 0 0 1 1 1 0 Spt20 family BAT2_N PF07001.11 CDJ43503.1 - 0.083 13.3 22.6 0.09 13.2 22.6 1.0 1 0 0 1 1 1 0 BAT2 N-terminus Herpes_capsid PF06112.11 CDJ43503.1 - 0.097 12.7 16.5 0.14 12.3 16.5 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TFIIA PF03153.13 CDJ43503.1 - 0.15 12.0 26.4 0.16 11.9 26.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 CDJ43503.1 - 0.17 11.2 4.4 0.22 10.9 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sporozoite_P67 PF05642.11 CDJ43503.1 - 0.17 9.9 11.1 0.2 9.7 11.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MPM1 PF17234.2 CDJ43503.1 - 0.66 10.2 12.2 0.88 9.8 12.2 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Roughex PF06020.11 CDJ43503.1 - 0.79 8.8 8.0 0.78 8.8 8.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF4175 PF13779.6 CDJ43503.1 - 1.2 7.0 15.1 1 7.2 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SPX PF03105.19 CDJ43503.1 - 1.3 8.9 24.8 1.4 8.8 24.8 1.0 1 0 0 1 1 1 0 SPX domain Tmemb_161AB PF10268.9 CDJ43503.1 - 1.3 7.6 2.7 1.8 7.1 2.7 1.2 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB Macoilin PF09726.9 CDJ43503.1 - 1.3 7.5 25.0 1.5 7.3 25.0 1.0 1 0 0 1 1 1 0 Macoilin family DUF1180 PF06679.12 CDJ43503.1 - 1.6 9.1 10.4 2 8.8 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PI3K_1B_p101 PF10486.9 CDJ43503.1 - 1.6 6.4 15.0 1.8 6.2 15.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Lin-8 PF03353.15 CDJ43503.1 - 2.7 7.5 19.2 3.2 7.2 19.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CAML PF14963.6 CDJ43503.1 - 3.4 7.7 13.4 3.8 7.6 13.4 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Gti1_Pac2 PF09729.9 CDJ43503.1 - 4.1 7.5 15.6 5.7 7.0 15.6 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family PNISR PF15996.5 CDJ43503.1 - 5 7.4 19.8 6.2 7.0 19.8 1.0 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SRP-alpha_N PF04086.13 CDJ43503.1 - 5.1 6.9 19.3 6.1 6.7 19.3 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal AF-4 PF05110.13 CDJ43503.1 - 5.7 4.9 30.0 9.9 4.1 30.0 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Membralin PF09746.9 CDJ43503.1 - 5.7 5.9 8.3 6.4 5.7 8.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein MscS_TM PF12794.7 CDJ43503.1 - 6 5.6 5.1 6.8 5.4 5.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Apt1 PF10351.9 CDJ43503.1 - 7 5.4 23.7 8.1 5.2 23.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 CDJ43503.1 - 7.3 5.9 13.4 8.3 5.7 13.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PAT1 PF09770.9 CDJ43503.1 - 9.5 4.4 18.1 9.6 4.3 18.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4667 PF15700.5 CDJ43505.1 - 1.2e-05 25.5 1.0 1.4e-05 25.3 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) SPX PF03105.19 CDJ43505.1 - 0.001 19.1 0.7 0.0011 19.0 0.7 1.2 1 0 0 1 1 1 1 SPX domain Sporozoite_P67 PF05642.11 CDJ43505.1 - 0.0052 14.9 7.7 0.0071 14.5 7.7 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF4598 PF15370.6 CDJ43505.1 - 0.0087 16.5 2.0 0.02 15.4 2.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) Peroxin-3 PF04882.12 CDJ43505.1 - 0.011 14.8 0.5 0.011 14.8 0.5 1.2 1 0 0 1 1 1 0 Peroxin-3 CCDC106 PF15794.5 CDJ43505.1 - 0.017 14.8 9.0 0.028 14.2 9.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Apt1 PF10351.9 CDJ43505.1 - 0.023 13.5 8.2 0.031 13.1 8.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AF-4 PF05110.13 CDJ43505.1 - 0.026 12.6 27.0 0.036 12.2 27.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Presenilin PF01080.17 CDJ43505.1 - 0.24 10.1 0.5 0.32 9.7 0.5 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 CDJ43505.1 - 0.29 9.6 9.4 0.41 9.1 9.4 1.2 1 0 0 1 1 1 0 Macoilin family NAM-associated PF14303.6 CDJ43505.1 - 0.31 11.7 7.0 0.51 11.0 7.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RSRP PF17069.5 CDJ43505.1 - 0.54 9.8 22.4 0.75 9.3 22.4 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 FmiP_Thoc5 PF09766.9 CDJ43505.1 - 1 8.6 6.2 10 5.3 2.2 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 BUD22 PF09073.10 CDJ43505.1 - 1.1 8.6 11.9 1.6 8.0 11.9 1.1 1 0 0 1 1 1 0 BUD22 PI3K_1B_p101 PF10486.9 CDJ43505.1 - 1.2 6.8 7.3 1.6 6.4 7.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Lin-8 PF03353.15 CDJ43505.1 - 1.2 8.6 4.5 2.3 7.7 4.5 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF1635 PF07795.11 CDJ43505.1 - 1.2 8.9 12.0 0.074 12.9 5.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) CCDC24 PF15669.5 CDJ43505.1 - 2.6 7.9 7.3 5.1 6.9 7.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF4614 PF15391.6 CDJ43505.1 - 2.8 7.9 17.3 4.6 7.2 17.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Secretin_N_2 PF07655.13 CDJ43505.1 - 4.5 7.9 20.9 8.3 7.0 20.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Macoilin PF09726.9 CDJ43506.1 - 0.11 11.0 7.8 0.12 10.9 7.8 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ43506.1 - 0.68 8.7 7.3 0.71 8.7 7.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tmemb_cc2 PF10267.9 CDJ43506.1 - 7.4 5.6 5.0 8.1 5.5 5.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein UTP25 PF06862.12 CDJ43508.1 - 3.3e-85 286.7 0.0 1.4e-52 179.1 0.0 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Arginase PF00491.21 CDJ43508.1 - 0.035 13.6 0.2 0.085 12.3 0.0 1.7 2 0 0 2 2 2 0 Arginase family DUF483 PF04467.12 CDJ43508.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF483) DUF2722 PF10846.8 CDJ43508.1 - 6.7 5.5 12.9 9.7 5.0 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ43508.1 - 7.2 6.5 17.6 0.36 10.8 11.8 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TraT PF05818.12 CDJ43509.1 - 0.82 9.3 6.5 1.2 8.8 6.5 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein TTRAP PF14203.6 CDJ43510.1 - 0.13 12.2 2.6 2.9 7.9 0.3 2.5 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Exonuc_VII_L PF02601.15 CDJ43510.1 - 0.34 10.4 18.4 0.44 10.1 18.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PMC2NT PF08066.12 CDJ43510.1 - 1.8 9.3 5.6 0.58 10.9 1.3 2.3 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF2228 PF10228.9 CDJ43510.1 - 2.3 7.9 13.0 1.2 8.8 0.7 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2228) MIS13 PF08202.11 CDJ43510.1 - 5.5 6.2 20.5 8.3 5.6 20.4 1.3 1 1 0 1 1 1 0 Mis12-Mtw1 protein family Prominin PF05478.11 CDJ43510.1 - 5.7 4.8 14.2 7.9 4.3 14.2 1.3 1 0 0 1 1 1 0 Prominin SPARC_Ca_bdg PF10591.9 CDJ43510.1 - 6.4 7.1 10.2 0.39 11.1 0.3 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Flavodoxin_1 PF00258.25 CDJ43511.1 - 3.4e-13 50.0 0.0 8e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin DUF3801 PF12687.7 CDJ43511.1 - 0.018 15.1 28.7 0.23 11.5 10.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) DUF2370 PF10176.9 CDJ43511.1 - 1.5 8.4 7.0 0.26 10.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) CCSAP PF15748.5 CDJ43511.1 - 2.6 8.2 31.6 1.5 8.9 8.1 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Apc15p PF05841.11 CDJ43512.1 - 5.3 7.9 13.2 3 8.7 0.1 3.2 2 1 1 3 3 3 0 Apc15p protein Suf PF05843.14 CDJ43512.1 - 8.9 6.2 15.0 6.2 6.7 7.4 2.5 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) Sec3_C PF09763.9 CDJ43513.1 - 0.025 13.0 3.0 0.026 12.9 3.0 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF4614 PF15391.6 CDJ43513.1 - 0.033 14.2 13.2 0.039 14.0 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Corona_nucleoca PF00937.18 CDJ43513.1 - 0.51 9.3 13.0 0.52 9.3 13.0 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Period_C PF12114.8 CDJ43513.1 - 1.6 8.3 15.4 1.7 8.2 15.4 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Apt1 PF10351.9 CDJ43513.1 - 1.8 7.3 9.2 1.6 7.5 9.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1635 PF07795.11 CDJ43513.1 - 3 7.6 9.1 3.5 7.4 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) RIFIN PF02009.16 CDJ43513.1 - 8.5 6.2 14.4 12 5.7 14.4 1.2 1 0 0 1 1 1 0 Rifin YjbE PF11106.8 CDJ43514.1 - 0.0044 17.2 2.0 0.0044 17.2 2.0 3.6 2 1 1 3 3 3 1 Exopolysaccharide production protein YjbE Lin-8 PF03353.15 CDJ43515.1 - 0.053 13.1 19.9 0.061 12.9 19.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sporozoite_P67 PF05642.11 CDJ43515.1 - 1.1 7.3 15.0 1.3 7.0 15.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BAF1_ABF1 PF04684.13 CDJ43515.1 - 1.1 8.2 16.7 1.4 7.9 16.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mcm10 PF09332.11 CDJ43515.1 - 2.5 7.4 21.9 3.5 7.0 21.9 1.2 1 0 0 1 1 1 0 Mcm10 replication factor DUF4746 PF15928.5 CDJ43515.1 - 2.8 7.3 7.7 3.3 7.1 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PAT1 PF09770.9 CDJ43515.1 - 9.3 4.4 35.0 10 4.2 35.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Transcrip_act PF04949.13 CDJ43516.1 - 0.21 11.5 1.8 0.38 10.6 1.8 1.3 1 0 0 1 1 1 0 Transcriptional activator DUF5327 PF17261.2 CDJ43516.1 - 0.36 11.6 3.1 0.77 10.5 3.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Dehydrin PF00257.19 CDJ43517.1 - 9.7 6.7 8.7 15 6.1 8.7 1.3 1 1 0 1 1 1 0 Dehydrin Peptidase_S8 PF00082.22 CDJ43518.1 - 0.0012 18.1 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Subtilase family EF-hand_6 PF13405.6 CDJ43518.1 - 0.68 10.0 2.8 2.1 8.5 2.8 1.8 1 0 0 1 1 1 0 EF-hand domain Bacteriocin_IIc PF10439.9 CDJ43519.1 - 2.1 8.5 10.1 0.25 11.5 5.8 1.7 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide PAT1 PF09770.9 CDJ43520.1 - 0.28 9.4 39.8 0.32 9.2 39.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IHABP4_N PF16174.5 CDJ43520.1 - 2.8 8.5 33.5 2.1 9.0 17.2 2.4 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal RR_TM4-6 PF06459.12 CDJ43520.1 - 4 7.2 21.9 1.4 8.7 17.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF5523 PF17661.1 CDJ43520.1 - 4.1 7.0 16.6 1.1 8.8 11.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) HCO3_cotransp PF00955.21 CDJ43520.1 - 9.3 4.9 5.7 13 4.4 5.7 1.3 1 0 0 1 1 1 0 HCO3- transporter family Med15 PF09606.10 CDJ43520.1 - 9.8 4.7 55.7 12 4.4 55.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PITH PF06201.13 CDJ43521.1 - 5e-16 59.3 0.0 8.4e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 PITH domain tRNA_int_endo PF01974.17 CDJ43521.1 - 2.9e-09 36.9 0.0 4.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Dsh_C PF12316.8 CDJ43521.1 - 0.01 16.2 17.6 0.016 15.6 17.6 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Apt1 PF10351.9 CDJ43521.1 - 0.1 11.5 4.9 0.11 11.4 4.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 CDJ43521.1 - 0.12 12.0 33.3 0.12 11.9 13.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ43521.1 - 1.6 9.1 30.3 0.94 9.8 9.1 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Secretin_N_2 PF07655.13 CDJ43521.1 - 9.7 6.8 17.4 13 6.4 2.0 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain BCDHK_Adom3 PF10436.9 CDJ43523.1 - 4.5e-08 33.1 0.2 9.2e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Pheromone PF08015.11 CDJ43523.1 - 9.5 7.3 20.2 9.7 7.3 2.3 2.5 2 0 0 2 2 2 0 Fungal mating-type pheromone Hydin_ADK PF17213.3 CDJ43524.1 - 0.33 11.2 26.8 0.16 12.2 17.4 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain FAM76 PF16046.5 CDJ43524.1 - 0.48 9.7 14.2 0.34 10.2 7.8 2.1 2 0 0 2 2 2 0 FAM76 protein MRC1 PF09444.10 CDJ43524.1 - 1.7 9.1 15.8 0.17 12.4 4.9 2.3 2 0 0 2 2 2 0 MRC1-like domain Exonuc_VII_L PF02601.15 CDJ43524.1 - 7 6.1 26.5 7 6.1 18.7 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Cellulose_synt PF03552.14 CDJ43527.1 - 0.0016 17.0 4.6 0.0022 16.6 4.6 1.1 1 0 0 1 1 1 1 Cellulose synthase Presenilin PF01080.17 CDJ43527.1 - 0.0037 16.1 12.6 0.0068 15.2 12.6 1.4 1 0 0 1 1 1 1 Presenilin DUF913 PF06025.12 CDJ43527.1 - 0.0042 16.1 3.7 0.0064 15.5 3.7 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 CDJ43527.1 - 0.0049 16.7 12.9 0.0082 16.0 12.9 1.3 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ43527.1 - 0.0052 15.8 11.4 0.0052 15.8 11.4 1.5 2 0 0 2 2 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.17 CDJ43527.1 - 0.0073 16.5 6.1 0.0073 16.5 6.1 1.6 2 0 0 2 2 2 1 DDHD domain DUF2370 PF10176.9 CDJ43527.1 - 0.033 13.9 3.2 0.057 13.1 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) V_ATPase_I PF01496.19 CDJ43527.1 - 0.033 12.1 14.3 0.047 11.6 13.3 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FAM60A PF15396.6 CDJ43527.1 - 0.033 14.2 7.0 0.065 13.2 7.0 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 CDJ43527.1 - 0.036 12.2 8.6 0.048 11.8 8.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pox_Ag35 PF03286.14 CDJ43527.1 - 0.049 13.4 8.0 0.079 12.7 8.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DAG_kinase_N PF14513.6 CDJ43527.1 - 0.055 13.7 14.2 0.078 13.2 11.3 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus SID-1_RNA_chan PF13965.6 CDJ43527.1 - 0.071 11.5 3.2 0.092 11.1 3.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PIP5K PF01504.18 CDJ43527.1 - 0.086 12.1 7.3 0.14 11.4 7.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase GAGA_bind PF06217.12 CDJ43527.1 - 0.13 12.6 11.1 0.27 11.5 8.7 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family CDC45 PF02724.14 CDJ43527.1 - 0.15 10.3 11.8 0.28 9.4 11.8 1.3 1 0 0 1 1 1 0 CDC45-like protein TERB2 PF15101.6 CDJ43527.1 - 0.2 11.7 20.0 0.049 13.7 16.0 1.9 2 0 0 2 2 2 0 Telomere-associated protein TERB2 CPSF100_C PF13299.6 CDJ43527.1 - 0.22 11.7 11.2 0.55 10.4 11.2 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Connexin PF00029.19 CDJ43527.1 - 0.22 11.2 10.6 0.44 10.3 10.6 1.4 1 0 0 1 1 1 0 Connexin CSG2 PF16965.5 CDJ43527.1 - 0.23 10.4 5.8 0.042 12.8 2.1 1.6 2 0 0 2 2 2 0 Ceramide synthase regulator EOS1 PF12326.8 CDJ43527.1 - 0.3 11.0 3.9 0.21 11.5 2.5 1.5 2 0 0 2 2 1 0 N-glycosylation protein DUF1980 PF09323.10 CDJ43527.1 - 0.35 10.8 7.1 0.1 12.5 4.2 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF1980) Hydin_ADK PF17213.3 CDJ43527.1 - 0.37 11.0 13.8 0.12 12.6 9.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Serinc PF03348.15 CDJ43527.1 - 0.37 9.7 5.3 0.63 8.9 5.3 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) CAML PF14963.6 CDJ43527.1 - 0.44 10.6 5.0 0.85 9.7 5.0 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF2339 PF10101.9 CDJ43527.1 - 0.62 8.6 23.8 0.74 8.3 23.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) TRAP_alpha PF03896.16 CDJ43527.1 - 0.73 9.0 6.7 1.4 8.0 6.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SpoIIP PF07454.11 CDJ43527.1 - 0.91 8.9 17.7 1.6 8.1 17.7 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4746 PF15928.5 CDJ43527.1 - 1 8.8 10.3 1.6 8.1 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ALMT PF11744.8 CDJ43527.1 - 1 8.1 13.7 1.6 7.4 13.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ43527.1 - 1.2 8.1 15.6 2.2 7.2 15.6 1.4 1 0 0 1 1 1 0 Solute carrier family 12 BORG_CEP PF14957.6 CDJ43527.1 - 1.3 10.1 11.9 0.69 11.1 9.6 1.6 2 0 0 2 2 1 0 Cdc42 effector DUF2126 PF09899.9 CDJ43527.1 - 1.5 6.8 11.3 2.1 6.3 11.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) EPL1 PF10513.9 CDJ43527.1 - 1.6 9.1 18.1 1.1 9.6 15.7 1.8 2 0 0 2 2 2 0 Enhancer of polycomb-like Pannexin_like PF12534.8 CDJ43527.1 - 2.1 7.4 11.5 3.3 6.7 11.5 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Paf1 PF03985.13 CDJ43527.1 - 2.3 7.2 23.2 3.6 6.5 23.2 1.2 1 0 0 1 1 1 0 Paf1 EIIBC-GUT_N PF03612.14 CDJ43527.1 - 2.3 7.9 13.2 6.7 6.4 13.2 1.8 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Spore_coat_CotO PF14153.6 CDJ43527.1 - 2.7 7.9 24.3 0.38 10.7 20.1 1.8 2 0 0 2 2 1 0 Spore coat protein CotO LMBR1 PF04791.16 CDJ43527.1 - 3 6.6 6.3 4.1 6.2 6.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CLN3 PF02487.17 CDJ43527.1 - 3.2 6.7 13.3 5.7 5.9 13.3 1.3 1 0 0 1 1 1 0 CLN3 protein Zip PF02535.22 CDJ43527.1 - 4 6.6 11.1 7.7 5.6 11.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter FAM176 PF14851.6 CDJ43527.1 - 4.1 7.1 12.3 9.2 5.9 12.3 1.5 1 0 0 1 1 1 0 FAM176 family Tim54 PF11711.8 CDJ43527.1 - 4.6 5.9 17.8 0.93 8.2 14.2 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Folate_carrier PF01770.18 CDJ43527.1 - 5.6 5.6 6.9 9.1 4.9 6.9 1.3 1 0 0 1 1 1 0 Reduced folate carrier Pal1 PF08316.11 CDJ43527.1 - 5.8 7.7 6.1 13 6.5 6.1 1.5 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF2828 PF11443.8 CDJ43527.1 - 7.1 4.6 17.2 15 3.6 17.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Baculo_PP31 PF05311.11 CDJ43527.1 - 7.2 6.0 13.2 12 5.3 13.2 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Membralin PF09746.9 CDJ43527.1 - 7.4 5.5 9.6 12 4.8 9.6 1.3 1 0 0 1 1 1 0 Tumour-associated protein Ureide_permease PF07168.11 CDJ43527.1 - 8.1 5.1 6.1 18 3.9 6.1 1.5 1 0 0 1 1 1 0 Ureide permease DUF4820 PF16091.5 CDJ43527.1 - 8.2 5.7 17.6 1.6 8.1 13.8 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4820) OATP PF03137.20 CDJ43527.1 - 8.4 4.5 6.6 13 3.9 6.6 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family VIR_N PF15912.5 CDJ43527.1 - 9.1 5.8 15.6 14 5.2 15.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF3408 PF11888.8 CDJ43527.1 - 9.7 6.3 20.7 21 5.2 20.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) TAF6_C PF07571.13 CDJ43528.1 - 4.6e-07 30.1 0.3 4.6e-07 30.1 0.3 2.3 2 1 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain Neur_chan_memb PF02932.16 CDJ43528.1 - 0.59 10.1 3.2 0.91 9.5 3.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ43528.1 - 3.3 6.4 8.5 5 5.8 8.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Draxin PF15550.6 CDJ43528.1 - 9.6 6.0 12.3 15 5.3 12.3 1.2 1 0 0 1 1 1 0 Draxin DUF2514 PF10721.9 CDJ43532.1 - 0.39 10.7 16.3 0.45 10.5 16.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Aldedh PF00171.22 CDJ43534.1 - 7.8e-32 110.4 0.0 1.2e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3522 PF12036.8 CDJ43537.1 - 1.4e-11 45.1 12.5 9.9e-06 26.0 0.9 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3522) Spt20 PF12090.8 CDJ43537.1 - 1.2 8.7 9.0 1.9 8.0 9.0 1.2 1 0 0 1 1 1 0 Spt20 family WBP-1 PF11669.8 CDJ43537.1 - 2.7 8.6 8.0 9.2 7.0 0.1 3.8 4 0 0 4 4 4 0 WW domain-binding protein 1 SUIM_assoc PF16619.5 CDJ43537.1 - 9.8 6.3 17.9 6.6 6.9 11.1 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 CDJ43538.1 - 5.8e-33 112.4 0.1 1.6e-07 31.9 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ43538.1 - 3.8e-14 52.7 0.0 0.0013 19.0 0.0 5.5 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ43538.1 - 0.00014 20.9 1.2 0.006 15.6 0.0 3.5 2 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ43538.1 - 0.0005 18.8 0.1 0.83 8.2 0.0 2.4 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 CDJ43538.1 - 0.00095 17.8 0.0 0.0074 14.9 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.11 CDJ43538.1 - 0.0046 16.9 0.0 0.25 11.2 0.0 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CDJ43538.1 - 0.0049 16.2 0.0 0.36 10.1 0.0 2.6 2 1 1 3 3 3 2 WD40-like domain Hira PF07569.11 CDJ43538.1 - 0.012 15.4 0.0 3.2 7.4 0.0 3.2 1 1 2 3 3 3 0 TUP1-like enhancer of split Mcl1_mid PF12341.8 CDJ43538.1 - 0.14 11.5 0.0 9.5 5.5 0.0 2.2 1 1 1 2 2 2 0 Minichromosome loss protein, Mcl1, middle region HEAT_2 PF13646.6 CDJ43540.1 - 9.9e-09 35.5 17.6 6.9e-08 32.8 3.1 8.6 5 3 3 8 8 8 3 HEAT repeats HEAT PF02985.22 CDJ43540.1 - 3.9e-08 32.9 43.7 9.2e-06 25.5 0.1 12.7 12 0 0 12 12 12 2 HEAT repeat HEAT_EZ PF13513.6 CDJ43540.1 - 9.8e-07 29.2 11.7 5.2e-06 26.8 1.9 14.2 8 5 8 16 16 16 2 HEAT-like repeat Cnd1 PF12717.7 CDJ43540.1 - 0.00013 22.0 0.4 0.39 10.7 0.1 3.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 SART-1 PF03343.13 CDJ43540.1 - 0.0064 15.1 1.9 0.011 14.4 1.9 1.3 1 0 0 1 1 1 1 SART-1 family SPX PF03105.19 CDJ43540.1 - 0.012 15.5 5.2 0.022 14.7 5.2 1.3 1 0 0 1 1 1 0 SPX domain Adaptin_N PF01602.20 CDJ43540.1 - 0.014 13.9 3.9 13 4.2 0.0 3.4 2 1 0 3 3 3 0 Adaptin N terminal region CLASP_N PF12348.8 CDJ43540.1 - 0.017 14.7 8.3 0.31 10.6 3.9 4.0 3 1 1 4 4 4 0 CLASP N terminal Spt20 PF12090.8 CDJ43540.1 - 0.023 14.3 13.3 0.013 15.1 4.5 2.7 2 0 0 2 2 2 0 Spt20 family RTP1_C1 PF10363.9 CDJ43540.1 - 0.039 14.1 4.0 0.07 13.3 0.1 3.6 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 UPF0147 PF03685.13 CDJ43540.1 - 0.047 13.7 0.1 3.1 7.9 0.0 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) Vac14_Fab1_bd PF12755.7 CDJ43540.1 - 0.075 13.6 0.0 7.7 7.2 0.0 3.6 2 1 3 5 5 5 0 Vacuolar 14 Fab1-binding region BP28CT PF08146.12 CDJ43540.1 - 0.091 12.6 0.2 0.53 10.1 0.2 2.3 2 0 0 2 2 2 0 BP28CT (NUC211) domain ParcG PF10274.9 CDJ43540.1 - 0.15 12.2 7.3 1.5 8.9 0.0 4.1 4 1 1 5 5 5 0 Parkin co-regulated protein Period_C PF12114.8 CDJ43540.1 - 4.4 6.9 12.3 11 5.6 12.3 1.6 1 0 0 1 1 1 0 Period protein 2/3C-terminal region MitMem_reg PF13012.6 CDJ43543.1 - 6.3e-32 110.3 1.3 8.5e-32 109.9 1.3 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CDJ43543.1 - 8.5e-05 22.5 0.9 0.00033 20.6 0.0 2.3 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RNase_J_C PF17770.1 CDJ43543.1 - 0.33 12.0 0.2 0.33 12.0 0.2 1.9 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain SelP_N PF04592.14 CDJ43544.1 - 6.2 6.2 11.8 0.041 13.3 1.7 2.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region TFIIA PF03153.13 CDJ43545.1 - 0.39 10.6 63.0 2.3 8.1 43.4 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3332 PF11810.8 CDJ43545.1 - 4.7 6.8 6.4 4.4 6.9 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3332) DUF1668 PF07893.13 CDJ43546.1 - 0.0086 15.5 1.3 0.0086 15.5 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1668) TFIIA PF03153.13 CDJ43546.1 - 0.043 13.8 27.0 0.05 13.6 27.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_coat_CotO PF14153.6 CDJ43546.1 - 0.085 12.8 15.0 0.1 12.5 15.0 1.0 1 0 0 1 1 1 0 Spore coat protein CotO PRP3 PF08572.10 CDJ43546.1 - 0.16 11.7 9.6 0.18 11.5 9.6 1.2 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) DUF4569 PF15133.6 CDJ43546.1 - 0.98 9.1 12.2 1.1 8.9 12.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Med15 PF09606.10 CDJ43546.1 - 1 7.9 23.1 1.1 7.8 23.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PepSY_TM PF03929.16 CDJ43546.1 - 1.4 8.5 3.0 1.6 8.3 3.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region EPL1 PF10513.9 CDJ43546.1 - 1.5 9.2 7.2 2.1 8.7 7.2 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Band_3_cyto PF07565.13 CDJ43546.1 - 2.2 8.0 8.1 2.6 7.8 8.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.17 CDJ43546.1 - 3.6 6.2 10.9 3.9 6.1 10.9 1.0 1 0 0 1 1 1 0 Presenilin DOR PF14839.6 CDJ43546.1 - 6.1 6.7 16.9 6.7 6.6 16.9 1.0 1 0 0 1 1 1 0 DOR family CCDC53 PF10152.9 CDJ43546.1 - 6.1 7.2 11.4 7.2 7.0 11.4 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DDHD PF02862.17 CDJ43546.1 - 7.9 6.6 8.9 9.3 6.3 8.9 1.1 1 0 0 1 1 1 0 DDHD domain Suf PF05843.14 CDJ43546.1 - 8.2 6.3 12.3 11 5.9 12.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CemA PF03040.14 CDJ43546.1 - 8.6 6.2 7.7 10 5.9 7.7 1.0 1 0 0 1 1 1 0 CemA family Activator_LAG-3 PF11498.8 CDJ43546.1 - 9.2 5.1 31.8 11 4.9 31.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 UPF0560 PF10577.9 CDJ43546.1 - 9.5 4.6 15.9 11 4.4 15.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SR-25 PF10500.9 CDJ43547.1 - 0.00079 19.1 0.9 0.00079 19.1 0.9 6.0 4 3 1 6 6 6 1 Nuclear RNA-splicing-associated protein AAA PF00004.29 CDJ43548.1 - 4.4e-41 140.4 0.0 9.2e-41 139.4 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ43548.1 - 6.4e-10 38.7 0.1 1.4e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CDJ43548.1 - 4e-06 27.1 0.2 0.0049 17.1 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 CDJ43548.1 - 8.8e-06 25.8 0.1 7.6e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ43548.1 - 6.6e-05 23.3 0.8 0.001 19.5 0.1 2.4 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CDJ43548.1 - 0.00017 21.4 0.0 0.00091 19.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDJ43548.1 - 0.00059 20.0 0.1 0.002 18.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 CDJ43548.1 - 0.0053 16.3 0.0 0.016 14.7 0.0 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 CDJ43548.1 - 0.0053 17.3 0.0 0.015 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CDJ43548.1 - 0.0057 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDJ43548.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDJ43548.1 - 0.011 15.4 0.2 0.044 13.5 0.1 2.1 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 CDJ43548.1 - 0.026 13.7 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CDJ43548.1 - 0.027 13.9 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 CDJ43548.1 - 0.029 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 CDJ43548.1 - 0.042 13.1 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activat PF00158.26 CDJ43548.1 - 0.062 13.0 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 CDJ43548.1 - 0.085 13.3 0.0 0.21 12.0 0.0 1.7 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 CDJ43548.1 - 0.098 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 CDJ43548.1 - 0.1 12.0 0.0 0.63 9.3 0.0 2.2 3 0 0 3 3 3 0 KaiC AAA_19 PF13245.6 CDJ43548.1 - 0.19 12.1 0.4 0.72 10.2 0.2 1.9 1 1 0 2 2 2 0 AAA domain TPR_11 PF13414.6 CDJ43551.1 - 0.022 14.4 0.1 0.044 13.5 0.1 1.5 1 0 0 1 1 1 0 TPR repeat TPR_19 PF14559.6 CDJ43551.1 - 0.077 13.5 0.6 0.41 11.2 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ43551.1 - 0.13 12.4 1.0 0.22 11.7 0.2 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Asp-B-Hydro_N PF05279.11 CDJ43552.1 - 0.9 9.6 12.4 0.98 9.4 12.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4638 PF15472.6 CDJ43552.1 - 1.7 8.3 11.0 1.8 8.2 11.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Phage_GPO PF05929.11 CDJ43552.1 - 9.6 5.7 20.1 11 5.6 20.1 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Ribosomal_S14 PF00253.21 CDJ43553.1 - 0.0012 18.6 0.6 0.0033 17.1 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e MORN PF02493.20 CDJ43554.1 - 2.6e-37 124.5 34.8 4.9e-07 29.3 1.2 6.2 6 0 0 6 6 6 6 MORN repeat HD_3 PF13023.6 CDJ43555.1 - 8.9e-26 90.8 0.0 1.1e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CDJ43555.1 - 2e-08 34.2 0.0 2.5e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CDJ43555.1 - 0.00027 21.1 0.0 0.00037 20.7 0.0 1.2 1 0 0 1 1 1 1 HD domain Presenilin PF01080.17 CDJ43556.1 - 1 8.1 4.3 0.39 9.4 1.4 1.9 2 0 0 2 2 2 0 Presenilin SR-25 PF10500.9 CDJ43557.1 - 0.0062 16.2 13.8 0.0062 16.2 13.8 2.2 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ43557.1 - 0.49 10.5 19.1 1.1 9.3 19.1 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF3446 PF11928.8 CDJ43557.1 - 3.5 8.0 13.1 1.2 9.5 5.3 2.8 3 0 0 3 3 3 0 Early growth response N-terminal domain Utp14 PF04615.13 CDJ43559.1 - 7.3 5.0 26.9 3.1 6.2 0.5 2.1 2 0 0 2 2 2 0 Utp14 protein TRAM_LAG1_CLN8 PF03798.16 CDJ43560.1 - 2.1e-17 63.6 7.7 2.6e-17 63.2 7.7 1.0 1 0 0 1 1 1 1 TLC domain HemY_N PF07219.13 CDJ43560.1 - 5.8e-05 23.2 0.1 0.0052 17.0 0.0 2.3 2 0 0 2 2 2 2 HemY protein N-terminus DUF3043 PF11241.8 CDJ43560.1 - 0.21 11.6 0.3 0.4 10.7 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) DUF2235 PF09994.9 CDJ43561.1 - 0.029 13.7 3.0 0.069 12.5 3.0 1.6 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) MecA PF05389.12 CDJ43561.1 - 0.16 11.6 6.1 1 9.0 1.7 2.6 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Connexin PF00029.19 CDJ43561.1 - 0.74 9.5 5.6 0.62 9.8 1.0 2.5 2 0 0 2 2 2 0 Connexin SAPS PF04499.15 CDJ43561.1 - 0.88 8.3 6.3 0.43 9.3 2.8 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Orf78 PF06024.12 CDJ43561.1 - 2.4 8.5 7.6 7.5 6.9 1.7 3.3 2 0 0 2 2 2 0 Orf78 (ac78) EOS1 PF12326.8 CDJ43561.1 - 2.7 7.9 4.6 2.2 8.2 0.1 2.8 3 0 0 3 3 3 0 N-glycosylation protein PAS_3 PF08447.12 CDJ43562.1 - 0.013 15.7 0.2 0.018 15.3 0.2 1.2 1 0 0 1 1 1 0 PAS fold TLD PF07534.16 CDJ43564.1 - 1e-10 42.0 0.3 1.3e-10 41.6 0.3 1.2 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 CDJ43564.1 - 4.1e-05 23.4 0.0 5.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IF-2B PF01008.17 CDJ43565.1 - 1.4e-34 119.6 0.0 1.7e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family WD40 PF00400.32 CDJ43566.1 - 0.02 15.8 0.0 17 6.5 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Peptidase_M16_C PF05193.21 CDJ43567.1 - 7.2e-06 26.1 1.4 9e-05 22.6 1.4 2.3 1 1 0 1 1 1 1 Peptidase M16 inactive domain PTPRCAP PF15713.5 CDJ43567.1 - 3.2 8.0 13.2 0.98 9.7 5.0 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Mut7-C PF01927.16 CDJ43568.1 - 6.3 6.9 7.4 12 6.0 2.2 3.4 3 0 0 3 3 3 0 Mut7-C RNAse domain Spt20 PF12090.8 CDJ43570.1 - 0.0016 18.1 5.8 0.0022 17.7 5.8 1.1 1 0 0 1 1 1 1 Spt20 family ELMO_CED12 PF04727.13 CDJ43570.1 - 0.034 14.3 0.4 0.63 10.1 0.0 2.3 2 0 0 2 2 2 0 ELMO/CED-12 family SUIM_assoc PF16619.5 CDJ43570.1 - 0.043 13.9 8.4 0.097 12.8 8.4 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ43570.1 - 0.059 13.4 11.0 0.085 12.8 11.0 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ43570.1 - 0.09 11.7 4.2 0.13 11.1 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ43570.1 - 2.5 6.7 10.3 0.27 9.9 4.3 1.9 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4217 PF13959.6 CDJ43571.1 - 1.9e-13 50.4 0.2 4.7e-13 49.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) HMG-CoA_red PF00368.18 CDJ43571.1 - 0.021 13.9 0.0 0.021 13.9 0.0 1.5 2 0 0 2 2 2 0 Hydroxymethylglutaryl-coenzyme A reductase RNA_pol_Rpc4 PF05132.14 CDJ43571.1 - 0.038 14.4 8.2 0.043 14.2 2.6 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 AAA_11 PF13086.6 CDJ43571.1 - 0.64 9.8 12.9 0.46 10.2 9.0 2.0 2 0 0 2 2 2 0 AAA domain CPSF100_C PF13299.6 CDJ43571.1 - 2.5 8.3 11.5 2.9 8.0 5.1 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Rtf2 PF04641.12 CDJ43571.1 - 2.9 7.2 20.0 3.1 7.1 13.7 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger DUF3807 PF12720.7 CDJ43571.1 - 5.9 7.1 24.6 4.1 7.6 17.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) EIIBC-GUT_N PF03612.14 CDJ43571.1 - 7.6 6.2 9.0 36 4.0 6.4 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus SpoIIP PF07454.11 CDJ43571.1 - 9.3 5.6 12.9 2.6 7.4 8.1 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Proteasome PF00227.26 CDJ43573.1 - 1.4e-59 200.8 0.0 1.9e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ43573.1 - 6.9e-10 38.4 0.9 1.6e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature TFIIA PF03153.13 CDJ43574.1 - 0.051 13.6 15.2 0.065 13.2 15.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dfp1_Him1_M PF08630.10 CDJ43574.1 - 0.49 10.6 2.9 0.98 9.6 2.9 1.5 1 0 0 1 1 1 0 Dfp1/Him1, central region IL28A PF15177.6 CDJ43574.1 - 0.65 9.8 9.7 0.39 10.5 7.7 1.6 1 1 0 1 1 1 0 Interleukin-28A SPX PF03105.19 CDJ43575.1 - 0.015 15.2 7.2 0.0046 16.9 1.9 2.3 2 1 0 2 2 2 0 SPX domain ANAPC4_WD40 PF12894.7 CDJ43576.1 - 3.7e-07 30.4 0.1 0.018 15.3 0.0 4.6 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ43576.1 - 7.9e-05 23.4 10.4 0.16 12.9 0.0 5.9 7 0 0 7 7 5 1 WD domain, G-beta repeat AF-4 PF05110.13 CDJ43576.1 - 0.0032 15.6 7.7 0.0042 15.3 7.7 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein UPF0524 PF15823.5 CDJ43576.1 - 0.0042 16.5 2.7 0.0074 15.7 2.7 1.4 1 0 0 1 1 1 1 UPF0524 of C3orf70 IMUP PF15761.5 CDJ43576.1 - 0.007 17.1 4.9 0.022 15.5 4.9 1.8 1 0 0 1 1 1 1 Immortalisation up-regulated protein RskA PF10099.9 CDJ43576.1 - 0.01 16.2 0.3 0.027 14.8 0.3 1.7 1 1 0 1 1 1 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ43576.1 - 0.011 15.3 11.1 0.021 14.4 11.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UPF0560 PF10577.9 CDJ43576.1 - 0.023 13.2 6.8 0.03 12.8 6.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TFIIA PF03153.13 CDJ43576.1 - 0.023 14.7 12.6 0.032 14.2 12.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1168 PF06658.12 CDJ43576.1 - 0.025 14.4 15.8 0.048 13.5 15.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) GREB1 PF15782.5 CDJ43576.1 - 0.038 11.1 3.6 0.045 10.9 3.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF755 PF05501.11 CDJ43576.1 - 0.068 13.4 23.4 0.17 12.2 23.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) NARP1 PF12569.8 CDJ43576.1 - 0.13 11.2 7.5 0.19 10.6 7.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Menin PF05053.13 CDJ43576.1 - 0.21 9.9 5.1 0.29 9.5 5.1 1.1 1 0 0 1 1 1 0 Menin DUF4746 PF15928.5 CDJ43576.1 - 0.73 9.2 4.2 1.1 8.6 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NEMP PF10225.9 CDJ43576.1 - 0.87 9.2 2.4 1.3 8.6 2.4 1.2 1 0 0 1 1 1 0 NEMP family Dehydrin PF00257.19 CDJ43576.1 - 1 9.9 7.6 2.1 8.9 7.6 1.5 1 0 0 1 1 1 0 Dehydrin Rrn6 PF10214.9 CDJ43576.1 - 1.4 7.3 17.7 2.4 6.5 17.7 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peptidase_S49_N PF08496.10 CDJ43576.1 - 2 8.4 7.3 4.3 7.4 7.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MAS20 PF02064.15 CDJ43576.1 - 3.6 7.7 10.8 7.1 6.7 10.8 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor Afi1 PF07792.12 CDJ43576.1 - 3.9 8.0 8.4 7.3 7.1 8.4 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking V_ATPase_I PF01496.19 CDJ43576.1 - 4.3 5.1 8.0 5.9 4.7 8.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 CDJ43576.1 - 5 7.1 5.0 8.1 6.4 5.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FH2 PF02181.23 CDJ43577.1 - 4.6e-16 58.9 0.0 4.6e-16 58.9 0.0 2.7 2 1 0 2 2 2 1 Formin Homology 2 Domain DDHD PF02862.17 CDJ43577.1 - 0.014 15.5 10.9 0.083 13.0 6.0 2.3 2 0 0 2 2 2 0 DDHD domain CPSF100_C PF13299.6 CDJ43577.1 - 0.026 14.7 14.0 1.1 9.4 8.6 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF2052 PF09747.9 CDJ43577.1 - 0.054 13.6 12.2 0.22 11.6 7.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Apc15p PF05841.11 CDJ43577.1 - 0.094 13.5 17.7 0.58 11.0 13.5 2.6 2 0 0 2 2 2 0 Apc15p protein EPL1 PF10513.9 CDJ43577.1 - 0.18 12.2 12.7 0.16 12.3 9.3 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like SpoIIP PF07454.11 CDJ43577.1 - 0.43 10.0 14.6 0.046 13.2 8.7 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 CDJ43577.1 - 0.49 8.6 8.9 0.046 12.0 3.9 1.7 2 0 0 2 2 2 0 CDC45-like protein ORC_WH_C PF18137.1 CDJ43577.1 - 0.53 10.3 17.6 1.5 8.9 8.4 2.5 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Exonuc_VII_L PF02601.15 CDJ43577.1 - 0.6 9.6 18.9 0.22 11.1 10.8 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit BRF1 PF07741.13 CDJ43577.1 - 0.68 10.3 22.4 0.68 10.3 3.5 2.7 2 0 0 2 2 2 0 Brf1-like TBP-binding domain CCSAP PF15748.5 CDJ43577.1 - 1 9.5 24.2 0.5 10.5 18.0 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated MecA PF05389.12 CDJ43577.1 - 1.2 8.7 12.6 2.7 7.6 8.2 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) RIFIN PF02009.16 CDJ43577.1 - 1.5 8.6 10.0 2.6 7.9 4.7 2.4 2 0 0 2 2 2 0 Rifin Lin-8 PF03353.15 CDJ43577.1 - 1.6 8.2 17.0 0.8 9.2 14.4 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist eIF-3_zeta PF05091.12 CDJ43577.1 - 2.1 7.2 18.2 0.11 11.4 12.8 1.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4471 PF14740.6 CDJ43577.1 - 2.9 7.0 9.2 0.12 11.5 3.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) DUF702 PF05142.12 CDJ43577.1 - 3.5 8.1 18.8 1 9.8 10.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) G0-G1_switch_2 PF15103.6 CDJ43577.1 - 4 7.9 12.9 11 6.5 7.8 2.9 2 0 0 2 2 2 0 G0/G1 switch protein 2 Presenilin PF01080.17 CDJ43577.1 - 4.5 5.9 20.6 1.7 7.3 16.6 1.9 2 0 0 2 2 2 0 Presenilin Folliculin PF11704.8 CDJ43577.1 - 6.6 6.6 15.1 5.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4407 PF14362.6 CDJ43577.1 - 6.7 6.0 23.5 0.93 8.8 10.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SPT16 PF08644.11 CDJ43577.1 - 7.1 6.8 12.0 51 4.0 8.8 2.3 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) TCP PF03634.13 CDJ43577.1 - 7.6 7.1 20.0 6.7 7.3 14.5 2.3 2 0 0 2 2 2 0 TCP family transcription factor Serinc PF03348.15 CDJ43577.1 - 8.7 5.1 6.8 15 4.3 6.8 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.12 CDJ43577.1 - 8.8 6.1 23.5 1.5 8.6 15.6 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Herpes_glycop PF01528.16 CDJ43578.1 - 0.063 12.1 0.0 0.074 11.9 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Thioredoxin_8 PF13905.6 CDJ43580.1 - 4.6e-19 68.5 0.0 7.5e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CDJ43580.1 - 7.7e-07 29.5 0.0 1.9e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CDJ43580.1 - 4.2e-05 23.4 0.0 0.00069 19.5 0.0 2.3 2 1 0 3 3 3 1 AhpC/TSA family Thioredoxin PF00085.20 CDJ43580.1 - 0.0013 18.7 0.1 0.015 15.3 0.1 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 CDJ43580.1 - 0.024 14.8 0.0 0.074 13.2 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like Kelch_5 PF13854.6 CDJ43581.1 - 1.6e-11 43.9 0.6 8e-06 25.7 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 CDJ43581.1 - 4.3e-08 33.0 0.6 0.0016 18.4 0.0 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ43581.1 - 1.3e-05 25.3 11.1 0.23 11.8 0.0 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ43581.1 - 0.00061 20.0 0.9 0.23 11.8 0.0 4.3 5 0 0 5 5 5 1 Kelch motif Peptidase_A22B PF04258.13 CDJ43582.1 - 4e-71 239.8 6.2 6.8e-71 239.1 6.2 1.3 1 1 0 1 1 1 1 Signal peptide peptidase TraX PF05857.11 CDJ43582.1 - 2.7 8.0 11.9 10 6.1 6.0 2.9 2 1 1 3 3 3 0 TraX protein MOZ_SAS PF01853.18 CDJ43583.1 - 1.5e-32 112.7 0.0 1e-30 106.7 0.1 2.2 1 1 1 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 CDJ43583.1 - 1.3e-18 66.4 0.2 2.8e-18 65.3 0.2 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CDJ43583.1 - 7.2e-11 41.8 0.0 1.9e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain Chromo PF00385.24 CDJ43586.1 - 0.00077 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-RING_2 PF13639.6 CDJ43587.1 - 3.4e-13 49.7 6.2 1e-12 48.2 6.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ43587.1 - 7.3e-10 38.5 5.9 2.1e-09 37.1 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ43587.1 - 4.1e-08 32.8 5.5 4.1e-08 32.8 5.5 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 CDJ43587.1 - 2.1e-07 30.8 2.9 6.2e-07 29.3 2.9 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ43587.1 - 4.3e-07 29.7 3.9 1e-06 28.5 3.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ43587.1 - 4.3e-07 30.1 8.0 5.8e-06 26.5 8.0 2.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CDJ43587.1 - 6.8e-06 25.9 5.5 1.5e-05 24.7 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ43587.1 - 0.00011 22.1 1.1 0.00011 22.1 1.1 2.4 1 1 1 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CDJ43587.1 - 0.0041 16.7 6.9 0.0094 15.6 6.9 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 CDJ43587.1 - 0.031 13.9 3.5 0.09 12.5 3.5 1.8 1 1 0 1 1 1 0 P-11 zinc finger Prok-RING_4 PF14447.6 CDJ43587.1 - 0.057 13.3 8.0 0.17 11.7 8.0 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CDJ43587.1 - 0.08 13.0 5.1 0.23 11.5 5.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CDJ43587.1 - 0.13 12.4 3.8 0.52 10.5 3.8 2.1 1 1 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 CDJ43587.1 - 0.31 11.1 4.4 0.9 9.6 4.4 1.9 1 0 0 1 1 1 0 Zinc-finger Alkyl_sulf_C PF14864.6 CDJ43589.1 - 7.4e-05 23.0 0.0 0.26 11.5 0.0 2.5 2 1 0 2 2 2 2 Alkyl sulfatase C-terminal TFIIA PF03153.13 CDJ43589.1 - 0.0028 17.7 15.1 0.0031 17.6 15.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ43589.1 - 0.0075 16.9 8.3 0.0092 16.6 8.3 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SCP2 PF02036.17 CDJ43589.1 - 0.008 16.6 0.1 0.018 15.5 0.1 1.7 1 1 0 1 1 1 1 SCP-2 sterol transfer family IHABP4_N PF16174.5 CDJ43589.1 - 0.015 15.9 11.1 0.021 15.4 11.1 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4228 PF14009.6 CDJ43589.1 - 0.037 14.4 0.5 0.045 14.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF5385 PF17359.2 CDJ43589.1 - 0.047 13.2 2.1 0.061 12.9 2.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Phostensin_N PF13916.6 CDJ43589.1 - 0.13 12.6 6.8 0.23 11.8 6.8 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Ndc1_Nup PF09531.10 CDJ43589.1 - 0.61 8.7 3.9 0.62 8.7 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AIF_C PF14721.6 CDJ43589.1 - 1.6 9.1 3.8 3.6 8.0 3.8 1.6 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3381 PF11861.8 CDJ43589.1 - 3.3 7.5 9.1 5.5 6.8 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4106 PF13388.6 CDJ43589.1 - 5.5 6.1 19.5 7.1 5.8 19.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Ribonuclease_3 PF00636.26 CDJ43590.1 - 4e-15 56.3 0.2 1.6e-10 41.5 0.1 3.3 2 1 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CDJ43590.1 - 3.9e-07 30.3 0.0 0.00035 20.7 0.0 2.6 3 0 0 3 3 3 2 Ribonuclease-III-like Spore_III_AB PF09548.10 CDJ43591.1 - 2.4 8.2 0.0 2.4 8.2 0.0 3.4 4 0 0 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) FAD_oxidored PF12831.7 CDJ43592.1 - 0.12 11.7 0.1 0.16 11.2 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Zein PF01559.16 CDJ43593.1 - 0.029 14.0 54.2 0.042 13.5 54.2 1.3 1 0 0 1 1 1 0 Zein seed storage protein Tic110 PF16940.5 CDJ43594.1 - 2.9 6.3 8.0 2.6 6.5 8.0 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter DUF3138 PF11336.8 CDJ43594.1 - 3.7 6.0 12.2 4.2 5.9 12.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Arm_3 PF16186.5 CDJ43595.1 - 0.034 13.7 0.1 0.062 12.9 0.1 1.4 1 0 0 1 1 1 0 Atypical Arm repeat SUIM_assoc PF16619.5 CDJ43595.1 - 0.047 13.8 7.4 0.1 12.7 7.4 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2721 PF11026.8 CDJ43596.1 - 0.023 14.6 0.2 0.023 14.6 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Utp14 PF04615.13 CDJ43596.1 - 5.3 5.5 36.8 6.9 5.1 36.8 1.1 1 0 0 1 1 1 0 Utp14 protein TPR_1 PF00515.28 CDJ43597.1 - 4.4e-07 29.5 4.9 0.19 11.6 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ43597.1 - 5e-05 23.1 14.0 0.056 13.6 0.0 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ43597.1 - 0.00019 21.7 23.1 0.0021 18.3 8.6 3.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ43597.1 - 0.013 15.4 7.3 0.2 11.6 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Spt20 PF12090.8 CDJ43597.1 - 0.04 13.5 3.6 0.062 12.9 3.6 1.3 1 0 0 1 1 1 0 Spt20 family TPR_8 PF13181.6 CDJ43597.1 - 0.05 13.8 2.9 26 5.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ43597.1 - 0.32 10.7 5.3 30 4.4 0.1 4.2 3 2 2 5 5 5 0 TPR repeat Pex26 PF07163.12 CDJ43597.1 - 0.54 9.5 6.6 1 8.6 0.8 2.3 2 0 0 2 2 2 0 Pex26 protein TPR_4 PF07721.14 CDJ43597.1 - 0.66 10.8 0.1 0.66 10.8 0.1 6.7 6 2 0 6 6 6 0 Tetratricopeptide repeat Hamartin PF04388.12 CDJ43598.1 - 5.8 5.5 36.3 8 5.0 36.3 1.3 1 0 0 1 1 1 0 Hamartin protein DUF4471 PF14740.6 CDJ43599.1 - 0.0003 20.1 5.4 0.00046 19.5 5.3 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4471) Lin-8 PF03353.15 CDJ43599.1 - 0.0068 16.0 12.4 0.0096 15.5 12.4 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 CDJ43599.1 - 0.0097 14.7 11.3 0.013 14.3 11.3 1.3 1 0 0 1 1 1 1 Presenilin SpoIIP PF07454.11 CDJ43599.1 - 0.013 15.0 11.9 0.018 14.5 11.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Eapp_C PF10238.9 CDJ43599.1 - 0.015 15.4 8.0 0.015 15.4 8.0 1.7 2 0 0 2 2 1 0 E2F-associated phosphoprotein EPL1 PF10513.9 CDJ43599.1 - 0.034 14.5 9.5 0.061 13.7 9.5 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like SLC12 PF03522.15 CDJ43599.1 - 0.044 12.8 9.5 0.061 12.3 9.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF4746 PF15928.5 CDJ43599.1 - 0.065 12.7 4.7 0.081 12.3 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2828 PF11443.8 CDJ43599.1 - 0.1 10.6 11.5 0.13 10.3 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4770 PF15994.5 CDJ43599.1 - 0.12 12.6 12.3 0.22 11.8 12.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) CTU2 PF10288.9 CDJ43599.1 - 0.14 12.4 11.8 0.4 10.9 11.8 1.8 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF3405 PF11885.8 CDJ43599.1 - 0.18 10.3 12.5 0.26 9.8 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) XRN_M PF17846.1 CDJ43599.1 - 0.2 10.6 6.4 0.31 10.0 6.4 1.3 1 0 0 1 1 1 0 Xrn1 helical domain FAM176 PF14851.6 CDJ43599.1 - 0.2 11.3 7.2 0.36 10.5 7.2 1.4 1 0 0 1 1 1 0 FAM176 family Connexin PF00029.19 CDJ43599.1 - 0.25 11.1 11.6 0.38 10.5 11.6 1.2 1 0 0 1 1 1 0 Connexin Plasmodium_Vir PF05795.11 CDJ43599.1 - 0.33 10.3 3.3 0.37 10.1 3.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3408 PF11888.8 CDJ43599.1 - 0.36 10.9 13.6 0.78 9.9 13.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Tim54 PF11711.8 CDJ43599.1 - 0.41 9.4 12.4 0.66 8.7 12.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Otopetrin PF03189.13 CDJ43599.1 - 0.44 9.3 2.9 0.51 9.1 2.9 1.2 1 0 0 1 1 1 0 Otopetrin DUF2370 PF10176.9 CDJ43599.1 - 0.61 9.7 5.2 0.76 9.4 4.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) RPA43_OB PF17875.1 CDJ43599.1 - 0.7 10.5 8.3 2.9 8.5 7.7 2.1 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF913 PF06025.12 CDJ43599.1 - 0.8 8.6 8.5 1.3 7.9 8.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MDM10 PF12519.8 CDJ43599.1 - 0.84 8.4 10.2 1.1 8.1 10.2 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 RR_TM4-6 PF06459.12 CDJ43599.1 - 0.85 9.4 13.9 1.5 8.6 13.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2126 PF09899.9 CDJ43599.1 - 1.1 7.2 9.3 1.7 6.6 9.3 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) MMR1 PF08505.10 CDJ43599.1 - 1.3 9.3 16.7 0.12 12.7 12.2 1.6 2 0 0 2 2 1 0 Mitochondrial Myo2 receptor-related protein FAM60A PF15396.6 CDJ43599.1 - 1.4 8.8 10.8 2.9 7.8 10.8 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 CDJ43599.1 - 1.5 6.8 12.6 2 6.5 12.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EIIBC-GUT_N PF03612.14 CDJ43599.1 - 1.8 8.3 12.5 4.1 7.1 12.5 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus ALMT PF11744.8 CDJ43599.1 - 1.8 7.3 9.9 2.4 6.9 9.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Membralin PF09746.9 CDJ43599.1 - 1.8 7.5 7.3 2.5 7.0 7.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein Sec62 PF03839.16 CDJ43599.1 - 2.2 7.7 9.9 3.8 7.0 9.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 eIF-3_zeta PF05091.12 CDJ43599.1 - 2.3 7.1 20.9 3.3 6.6 20.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ORC_WH_C PF18137.1 CDJ43599.1 - 2.5 8.2 15.9 6 6.9 15.9 1.6 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Mid2 PF04478.12 CDJ43599.1 - 2.5 7.9 0.0 2.5 7.9 0.0 2.1 2 0 0 2 2 1 0 Mid2 like cell wall stress sensor CAF1 PF04857.20 CDJ43599.1 - 3 6.9 10.7 2.2 7.4 5.9 2.1 2 0 0 2 2 2 0 CAF1 family ribonuclease DUF4638 PF15472.6 CDJ43599.1 - 4.5 6.9 13.1 7.1 6.3 13.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF4449 PF14613.6 CDJ43599.1 - 5.3 7.1 18.9 0.69 10.0 14.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) OATP PF03137.20 CDJ43599.1 - 5.4 5.2 7.6 7.1 4.8 7.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TERB2 PF15101.6 CDJ43599.1 - 6.4 6.8 22.8 12 5.8 22.8 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Band_3_cyto PF07565.13 CDJ43599.1 - 6.6 6.5 15.9 12 5.6 15.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PIP5K PF01504.18 CDJ43599.1 - 6.7 5.8 13.8 9.7 5.3 13.8 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CLN3 PF02487.17 CDJ43599.1 - 7 5.6 12.6 11 4.9 12.6 1.2 1 0 0 1 1 1 0 CLN3 protein NPL PF17800.1 CDJ43599.1 - 7.5 7.2 8.5 5.4 7.6 0.3 2.5 2 0 0 2 2 2 0 Nucleoplasmin-like domain Folate_carrier PF01770.18 CDJ43599.1 - 8.1 5.1 10.4 13 4.4 10.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier SR-25 PF10500.9 CDJ43600.1 - 0.58 9.7 13.3 0.83 9.2 13.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ43600.1 - 0.75 10.5 10.6 0.14 12.8 7.1 1.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF262 PF03235.14 CDJ43601.1 - 0.042 14.0 7.3 0.068 13.3 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 DDRGK PF09756.9 CDJ43601.1 - 4.2 6.9 42.0 8.1 6.0 42.0 1.4 1 0 0 1 1 1 0 DDRGK domain SpoIIP PF07454.11 CDJ43601.1 - 5.1 6.5 14.3 10 5.5 14.3 1.6 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PAT1 PF09770.9 CDJ43601.1 - 6.4 4.9 22.8 11 4.2 22.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAF-AH_p_II PF03403.13 CDJ43601.1 - 6.9 5.1 12.4 11 4.5 12.4 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II NPR3 PF03666.13 CDJ43601.1 - 8.6 5.0 19.4 14 4.3 19.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FRQ PF09421.10 CDJ43604.1 - 0.0023 16.1 19.1 0.0027 15.9 19.1 1.0 1 0 0 1 1 1 1 Frequency clock protein DUF1168 PF06658.12 CDJ43604.1 - 0.23 11.3 18.4 0.31 10.9 18.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF1180 PF06679.12 CDJ43604.1 - 0.41 11.0 18.9 0.62 10.5 18.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Lin-8 PF03353.15 CDJ43604.1 - 0.43 10.1 25.1 0.48 9.9 25.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CCDC24 PF15669.5 CDJ43604.1 - 0.81 9.5 15.7 1 9.2 15.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF2052 PF09747.9 CDJ43604.1 - 1.4 9.0 14.0 1.7 8.7 14.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) V_ATPase_I PF01496.19 CDJ43604.1 - 1.7 6.5 14.3 1.9 6.3 14.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RAP1 PF07218.11 CDJ43604.1 - 1.7 6.8 7.4 1.6 6.9 7.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 CDJ43604.1 - 2 6.9 18.3 2.3 6.7 18.3 1.0 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 CDJ43604.1 - 2.4 7.1 16.3 2.7 6.9 16.3 1.0 1 0 0 1 1 1 0 Mitoguardin GAGA_bind PF06217.12 CDJ43604.1 - 3.1 8.0 14.4 3.4 7.9 14.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DAG_kinase_N PF14513.6 CDJ43604.1 - 3.1 8.0 15.3 4.3 7.5 15.3 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus SPX PF03105.19 CDJ43604.1 - 3.3 7.5 24.1 3.9 7.3 24.1 1.0 1 0 0 1 1 1 0 SPX domain DUF3807 PF12720.7 CDJ43604.1 - 4.1 7.6 20.1 5.4 7.2 20.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Peptidase_S30 PF01577.16 CDJ43604.1 - 5 6.7 10.6 6.5 6.3 10.6 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease Paf1 PF03985.13 CDJ43604.1 - 5.2 6.0 19.9 6.5 5.6 19.9 1.1 1 0 0 1 1 1 0 Paf1 BORG_CEP PF14957.6 CDJ43604.1 - 5.3 8.2 17.4 8.5 7.6 17.4 1.3 1 0 0 1 1 1 0 Cdc42 effector Menin PF05053.13 CDJ43604.1 - 5.4 5.2 15.5 6.6 5.0 15.5 1.2 1 0 0 1 1 1 0 Menin ATP11 PF06644.11 CDJ43604.1 - 6.1 6.5 15.9 9.8 5.9 15.9 1.3 1 0 0 1 1 1 0 ATP11 protein DDRGK PF09756.9 CDJ43604.1 - 6.5 6.3 14.9 7.9 6.0 14.9 1.1 1 0 0 1 1 1 0 DDRGK domain Peptidase_S64 PF08192.11 CDJ43604.1 - 9.9 4.5 19.1 12 4.3 19.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.10 CDJ43605.1 - 0.042 12.6 8.5 0.059 12.1 8.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ43605.1 - 0.34 9.6 4.6 0.46 9.2 4.6 1.3 1 0 0 1 1 1 0 Presenilin Activator_LAG-3 PF11498.8 CDJ43605.1 - 1.3 7.9 33.4 1.1 8.2 16.3 2.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 FAM176 PF14851.6 CDJ43605.1 - 1.4 8.5 6.4 7.2 6.3 2.4 2.3 2 0 0 2 2 2 0 FAM176 family adh_short PF00106.25 CDJ43606.1 - 1.5e-35 122.4 0.0 2e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ43606.1 - 1.2e-21 77.4 0.0 1.5e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ43606.1 - 4.5e-10 39.7 0.0 6.6e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CDJ43606.1 - 3.1e-05 23.3 0.0 3.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 CDJ43606.1 - 0.0032 17.0 0.2 0.01 15.3 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 CDJ43606.1 - 0.0044 17.6 0.1 0.0079 16.8 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 CDJ43606.1 - 0.0077 16.1 0.4 0.011 15.6 0.4 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 CDJ43606.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Nop10p PF04135.12 CDJ43607.1 - 0.58 10.3 2.7 26 4.9 0.2 2.4 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family DUF445 PF04286.12 CDJ43608.1 - 3.7e-08 33.6 24.6 4.4e-08 33.3 24.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) RHD3 PF05879.12 CDJ43608.1 - 0.00033 19.0 22.2 0.00044 18.6 22.2 1.3 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) SR-25 PF10500.9 CDJ43608.1 - 0.2 11.3 36.5 0.11 12.2 23.0 2.5 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein RNase_J_C PF17770.1 CDJ43608.1 - 2.5 9.2 20.9 1.8e+04 -7.3 20.9 3.4 1 1 0 1 1 1 0 Ribonuclease J C-terminal domain Peptidase_S46 PF10459.9 CDJ43608.1 - 9.2 4.8 32.7 9.4 4.7 32.7 1.1 1 0 0 1 1 1 0 Peptidase S46 BatD PF13584.6 CDJ43609.1 - 0.021 13.7 4.0 0.025 13.4 4.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance DUF5313 PF17240.2 CDJ43609.1 - 0.039 14.4 0.1 0.056 13.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5313) Presenilin PF01080.17 CDJ43609.1 - 0.32 9.7 11.8 0.35 9.6 11.8 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ43609.1 - 0.38 10.5 4.1 0.5 10.2 4.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SPX PF03105.19 CDJ43609.1 - 0.55 10.1 18.1 0.61 10.0 18.1 1.1 1 0 0 1 1 1 0 SPX domain Ribosomal_L12_N PF16320.5 CDJ43609.1 - 0.97 9.2 12.5 1.6 8.5 12.5 1.3 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain Apt1 PF10351.9 CDJ43609.1 - 1.3 7.7 21.8 1.6 7.5 21.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 CDJ43609.1 - 1.4 8.1 8.7 1.8 7.7 8.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Med24_N PF11277.8 CDJ43609.1 - 2.2 6.2 7.4 2.7 5.9 7.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal CDC45 PF02724.14 CDJ43609.1 - 2.2 6.5 13.5 2.6 6.2 13.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 CDJ43609.1 - 4.1 5.4 12.5 4.2 5.4 12.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 CDJ43609.1 - 4.5 7.3 7.6 5.8 6.9 7.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.13 CDJ43609.1 - 7.2 5.3 16.6 9.2 4.9 16.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1517 PF07466.11 CDJ43610.1 - 0.077 13.1 0.3 0.16 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Med3 PF11593.8 CDJ43611.1 - 3.7 6.6 18.8 5.2 6.2 18.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Metallopep PF12044.8 CDJ43612.1 - 0.055 12.1 0.1 0.091 11.4 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase family ubiquitin PF00240.23 CDJ43613.1 - 4.7e-22 77.5 0.5 5.3e-22 77.4 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ43613.1 - 4.2e-10 39.3 0.3 5.2e-10 39.0 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ43613.1 - 7e-06 26.4 0.5 2.8e-05 24.5 0.5 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CDJ43613.1 - 0.0047 17.3 0.1 0.0055 17.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 CDJ43613.1 - 0.0086 16.6 0.1 0.0087 16.6 0.1 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CDJ43613.1 - 0.071 13.2 0.3 2.9 8.0 0.1 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain ThiS PF02597.20 CDJ43613.1 - 0.12 13.1 0.1 0.14 12.8 0.1 1.1 1 0 0 1 1 1 0 ThiS family SUIM_assoc PF16619.5 CDJ43614.1 - 3.6e-05 23.7 11.6 0.0047 16.9 1.1 2.6 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 DUF3446 PF11928.8 CDJ43614.1 - 0.12 12.7 9.2 0.19 12.0 6.0 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF2195 PF09961.9 CDJ43614.1 - 0.5 10.3 2.1 0.39 10.7 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2195) DUF1645 PF07816.11 CDJ43614.1 - 1.3 9.6 7.8 0.22 12.1 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) TFIIA PF03153.13 CDJ43614.1 - 2.2 8.2 22.3 0.76 9.7 6.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ43614.1 - 5.4 6.6 15.2 0.4 10.3 9.0 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Virul_Fac PF10139.9 CDJ43615.1 - 1.6 6.8 10.8 2 6.6 10.8 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor SAP130_C PF16014.5 CDJ43615.1 - 5.7 5.9 15.7 6.4 5.7 15.7 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Phosducin PF02114.16 CDJ43616.1 - 1.2e-08 34.3 0.0 1.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Phosducin Succ_CoA_lig PF13607.6 CDJ43616.1 - 0.0022 17.8 0.1 0.21 11.4 0.0 2.3 1 1 1 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain DUF2722 PF10846.8 CDJ43616.1 - 0.0031 16.6 0.3 0.0036 16.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Med3 PF11593.8 CDJ43616.1 - 3.1 6.9 10.0 3.7 6.6 10.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Androgen_recep PF02166.16 CDJ43616.1 - 7.1 5.3 14.3 2.4 6.9 10.3 1.9 2 0 0 2 2 2 0 Androgen receptor Dynamin_N PF00350.23 CDJ43618.1 - 3e-09 37.1 0.0 4.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Dynamin family DUF4628 PF15429.6 CDJ43618.1 - 0.016 14.9 0.3 0.024 14.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) MMR_HSR1 PF01926.23 CDJ43618.1 - 0.08 13.0 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase BAF1_ABF1 PF04684.13 CDJ43619.1 - 0.15 11.1 7.4 0.16 11.0 7.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.8 CDJ43619.1 - 2 8.0 19.2 2 8.0 19.2 1.1 1 0 0 1 1 1 0 Spt20 family COG2 PF06148.11 CDJ43620.1 - 2.9 8.0 9.0 16 5.6 5.9 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 INO80_Ies4 PF08193.11 CDJ43620.1 - 9.1 6.2 10.1 0.31 11.0 3.6 1.9 2 0 0 2 2 2 0 INO80 complex subunit Ies4 EIF4E-T PF10477.9 CDJ43622.1 - 1.3 7.7 7.7 1.5 7.5 7.7 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF1840 PF08895.11 CDJ43622.1 - 2.3 8.6 11.7 2.5 8.5 5.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) TFIIA PF03153.13 CDJ43622.1 - 6.8 6.6 21.7 10 6.0 21.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ43622.1 - 8.4 7.1 27.6 2.3 8.9 1.4 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF2742 PF10888.8 CDJ43623.1 - 0.0018 18.5 0.1 0.0063 16.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2742) Bromodomain PF00439.25 CDJ43624.1 - 4e-17 62.1 0.0 7.2e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain Spt20 PF12090.8 CDJ43624.1 - 0.00018 21.2 17.2 0.00026 20.7 17.2 1.1 1 0 0 1 1 1 1 Spt20 family eIF3_p135 PF12807.7 CDJ43624.1 - 0.015 15.3 0.3 0.024 14.7 0.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 TERB2 PF15101.6 CDJ43624.1 - 0.019 15.0 4.3 0.025 14.7 4.3 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF963 PF06131.11 CDJ43624.1 - 0.11 11.9 8.6 0.16 11.4 4.2 2.4 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF2722 PF10846.8 CDJ43624.1 - 0.13 11.1 14.3 0.18 10.7 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RIFIN PF02009.16 CDJ43624.1 - 0.15 11.9 3.2 0.32 10.8 3.2 1.5 1 0 0 1 1 1 0 Rifin KGK PF08872.10 CDJ43624.1 - 0.39 11.2 3.8 0.6 10.6 3.8 1.2 1 0 0 1 1 1 0 KGK domain EIF4E-T PF10477.9 CDJ43624.1 - 0.51 9.1 9.2 0.63 8.8 9.2 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Folliculin PF11704.8 CDJ43624.1 - 1.3 8.9 6.0 2 8.3 6.0 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport NACHT_N PF17100.5 CDJ43624.1 - 1.3 8.8 9.4 2 8.2 9.4 1.2 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase DUF4834 PF16118.5 CDJ43624.1 - 2.6 9.1 5.3 4 8.5 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) UPF0560 PF10577.9 CDJ43624.1 - 5.3 5.4 13.0 7 5.0 13.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 V_ATPase_I PF01496.19 CDJ43625.1 - 1.4 6.7 20.0 2.2 6.1 20.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAT1 PF09770.9 CDJ43625.1 - 3.3 5.9 53.3 0.044 12.1 43.9 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 P34-Arc PF04045.14 CDJ43626.1 - 0.091 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Arp2/3 complex, 34 kD subunit p34-Arc TFIIA PF03153.13 CDJ43627.1 - 0.055 13.5 23.4 0.074 13.0 23.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ43627.1 - 0.28 11.1 8.9 0.42 10.6 8.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ43627.1 - 0.82 8.4 6.6 1.1 7.9 6.6 1.1 1 0 0 1 1 1 0 Presenilin RskA PF10099.9 CDJ43627.1 - 0.82 9.9 33.2 42 4.4 33.2 2.2 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ43627.1 - 1 10.0 25.5 1.8 9.2 6.2 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pes-10 PF07149.11 CDJ43628.1 - 0.018 14.1 32.0 0.027 13.6 32.0 1.1 1 0 0 1 1 1 0 Pes-10 Nop14 PF04147.12 CDJ43628.1 - 0.075 11.2 35.1 0.1 10.8 35.1 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 CDJ43628.1 - 0.11 11.9 23.7 0.16 11.4 23.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid_p PF12226.8 CDJ43628.1 - 2 7.5 17.6 3.1 6.8 17.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TRAP_alpha PF03896.16 CDJ43628.1 - 3.1 6.9 18.2 8.1 5.6 18.2 1.7 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.11 CDJ43628.1 - 5.3 5.5 17.3 7 5.1 17.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Na_trans_assoc PF06512.13 CDJ43628.1 - 7 6.9 33.7 11 6.2 33.7 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DUF4045 PF13254.6 CDJ43628.1 - 8.8 5.8 28.2 16 5.0 28.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CLP1_N PF16573.5 CDJ43629.1 - 7e-11 42.2 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor YqfQ PF14181.6 CDJ43629.1 - 0.6 10.3 7.5 1.3 9.2 7.5 1.6 1 0 0 1 1 1 0 YqfQ-like protein ACDC PF14733.6 CDJ43630.1 - 5.1e-14 52.3 0.5 5.9e-14 52.2 0.5 1.0 1 0 0 1 1 1 1 AP2-coincident C-terminal MRI PF15325.6 CDJ43631.1 - 3 9.0 21.6 0.2 12.8 0.6 3.5 3 0 0 3 3 3 0 Modulator of retrovirus infection Dehydrin PF00257.19 CDJ43632.1 - 0.031 14.8 3.0 0.031 14.8 3.0 2.3 2 1 0 2 2 2 0 Dehydrin FAM60A PF15396.6 CDJ43632.1 - 0.04 13.9 1.3 2.1 8.3 1.3 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Presenilin PF01080.17 CDJ43632.1 - 0.088 11.6 5.6 0.13 11.0 5.6 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ43632.1 - 3.5 8.6 11.0 19 6.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CAF20 PF17052.5 CDJ43632.1 - 5.7 7.1 9.9 34 4.5 0.0 2.2 2 0 0 2 2 2 0 Cap associated factor Cation_efflux PF01545.21 CDJ43633.1 - 0.024 14.4 9.9 0.77 9.4 4.3 3.4 3 1 0 3 3 3 0 Cation efflux family SUR7 PF06687.12 CDJ43633.1 - 0.29 10.8 9.5 3 7.4 0.0 2.5 2 1 0 2 2 2 0 SUR7/PalI family Neur_chan_memb PF02932.16 CDJ43634.1 - 0.061 13.4 13.6 1.3 9.0 0.0 3.1 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF4179 PF13786.6 CDJ43634.1 - 0.087 13.3 0.1 0.087 13.3 0.1 4.2 4 1 0 4 4 4 0 Domain of unknown function (DUF4179) CybS PF05328.12 CDJ43634.1 - 0.27 10.9 1.4 3.2 7.4 0.0 2.6 3 0 0 3 3 3 0 CybS, succinate dehydrogenase cytochrome B small subunit VPDSG-CTERM PF18205.1 CDJ43634.1 - 4.2 7.3 8.2 22 5.0 8.2 2.4 1 0 0 1 1 1 0 VPDSG-CTERM motif SR-25 PF10500.9 CDJ43635.1 - 0.15 11.7 17.7 0.31 10.6 17.7 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF572 PF04502.13 CDJ43635.1 - 0.6 9.7 12.5 0.81 9.2 12.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4407 PF14362.6 CDJ43635.1 - 4.8 6.4 19.3 6.5 6.0 19.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 CDJ43635.1 - 5.3 5.7 14.9 8.2 5.1 14.9 1.3 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ43635.1 - 9.1 6.3 12.5 12 5.9 12.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SUIM_assoc PF16619.5 CDJ43637.1 - 1.9 8.6 48.8 0.23 11.5 3.9 4.1 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Thioredoxin_8 PF13905.6 CDJ43638.1 - 1.2e-19 70.4 0.0 1.7e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Hydrolase PF00702.26 CDJ43640.1 - 6.8e-07 29.8 0.1 1.2e-06 29.0 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ43640.1 - 0.00015 21.8 0.0 0.00055 20.0 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Fer4_8 PF13183.6 CDJ43642.1 - 0.048 14.1 1.4 0.072 13.6 1.4 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain SR-25 PF10500.9 CDJ43642.1 - 0.096 12.3 5.2 0.13 11.9 5.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NINJA_B PF16136.5 CDJ43642.1 - 0.13 12.6 5.5 0.17 12.2 5.5 1.3 1 0 0 1 1 1 0 Putative nuclear localisation signal Spt20 PF12090.8 CDJ43642.1 - 0.33 10.5 3.3 0.35 10.4 3.3 1.0 1 0 0 1 1 1 0 Spt20 family CtnDOT_TraJ PF07863.11 CDJ43642.1 - 4.8 7.9 7.4 6 7.6 0.2 2.2 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon Lactamase_B_2 PF12706.7 CDJ43644.1 - 5.3e-11 42.4 0.0 7.5e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ43644.1 - 0.067 13.2 0.5 0.46 10.5 0.5 2.3 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily E1_FCCH PF16190.5 CDJ43645.1 - 1.3e-17 63.8 0.0 2.3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain ThiF PF00899.21 CDJ43645.1 - 9.4e-14 51.4 0.0 4.9e-09 35.9 2.1 3.1 2 1 0 2 2 2 2 ThiF family E1_4HB PF16191.5 CDJ43645.1 - 1.6e-05 25.0 1.9 1.6e-05 25.0 1.9 2.4 2 1 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Ribosomal_60s PF00428.19 CDJ43645.1 - 0.06 13.9 0.4 0.06 13.9 0.4 4.9 3 2 1 4 4 4 0 60s Acidic ribosomal protein 2-Hacid_dh_C PF02826.19 CDJ43645.1 - 0.064 12.6 0.1 0.16 11.3 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FoP_duplication PF13865.6 CDJ43645.1 - 0.11 13.1 0.5 0.11 13.1 0.5 2.8 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 DUF4834 PF16118.5 CDJ43645.1 - 1.6 9.7 10.9 40 5.2 2.8 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) CNDH2_M PF16869.5 CDJ43645.1 - 4.5 8.0 10.0 1.7 9.3 0.1 3.1 3 0 0 3 3 3 0 PF16858 SUIM_assoc PF16619.5 CDJ43645.1 - 8.4 6.5 39.9 0.12 12.5 4.7 3.7 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Zip PF02535.22 CDJ43647.1 - 1.3e-14 54.2 5.2 1.3e-14 54.2 5.2 2.1 2 0 0 2 2 2 1 ZIP Zinc transporter UPF0515 PF15135.6 CDJ43647.1 - 0.078 12.3 1.7 0.11 11.8 1.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 SLATT_5 PF18160.1 CDJ43647.1 - 0.085 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF3824 PF12868.7 CDJ43647.1 - 0.15 12.7 3.3 0.25 12.0 3.3 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF3792 PF12670.7 CDJ43647.1 - 0.19 11.9 4.5 0.47 10.6 4.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Ribosomal_60s PF00428.19 CDJ43647.1 - 0.82 10.3 5.9 0.44 11.2 3.4 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein SelP_N PF04592.14 CDJ43647.1 - 2.4 7.5 10.1 3.4 7.0 10.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CDK2AP PF09806.9 CDJ43649.1 - 0.00055 20.1 20.6 0.00058 20.0 14.9 2.1 2 0 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein RskA PF10099.9 CDJ43649.1 - 0.012 16.0 2.6 0.015 15.6 2.6 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF1645 PF07816.11 CDJ43649.1 - 0.021 15.4 15.3 0.021 15.4 15.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Plasmodium_Vir PF05795.11 CDJ43649.1 - 0.036 13.5 12.8 0.046 13.1 12.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein VIR_N PF15912.5 CDJ43649.1 - 0.06 12.9 5.6 0.067 12.8 5.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal MAT1 PF06391.13 CDJ43649.1 - 0.094 12.5 14.6 0.14 11.9 14.6 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 TFIIA PF03153.13 CDJ43649.1 - 0.13 12.3 28.2 0.16 12.0 28.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ43649.1 - 0.2 9.5 8.2 0.21 9.5 8.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Membralin PF09746.9 CDJ43649.1 - 0.31 10.1 7.0 0.38 9.7 7.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein SID-1_RNA_chan PF13965.6 CDJ43649.1 - 0.33 9.3 3.5 0.46 8.8 3.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MCU PF04678.13 CDJ43649.1 - 1.1 9.3 7.4 1.6 8.8 7.4 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4407 PF14362.6 CDJ43649.1 - 1.2 8.4 7.7 1.5 8.1 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0524 PF15823.5 CDJ43649.1 - 1.6 8.1 15.6 2.6 7.4 15.6 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 SLC12 PF03522.15 CDJ43649.1 - 1.9 7.4 16.9 2.2 7.2 16.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PI3K_1B_p101 PF10486.9 CDJ43649.1 - 3.6 5.3 17.0 5.5 4.6 17.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PAT1 PF09770.9 CDJ43649.1 - 4 5.6 20.1 4.6 5.4 20.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 XRN_M PF17846.1 CDJ43649.1 - 4 6.3 9.8 5 6.0 9.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Med24_N PF11277.8 CDJ43649.1 - 4 5.3 11.5 4.6 5.2 11.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal SDP_N PF12278.8 CDJ43649.1 - 4.5 7.4 25.3 0.088 12.9 17.0 1.9 2 0 0 2 2 2 0 Sex determination protein N terminal SPX PF03105.19 CDJ43649.1 - 5.1 6.9 26.2 7.3 6.4 26.2 1.2 1 0 0 1 1 1 0 SPX domain GREB1 PF15782.5 CDJ43649.1 - 5.5 4.0 24.8 6.8 3.7 24.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAP1 PF08601.10 CDJ43649.1 - 5.9 6.5 29.8 9.4 5.8 29.8 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Smg8_Smg9 PF10220.9 CDJ43649.1 - 6.3 5.0 17.1 7.1 4.8 17.1 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Hid1 PF12722.7 CDJ43649.1 - 7.7 4.5 19.1 9.4 4.2 19.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCSAP PF15748.5 CDJ43649.1 - 7.9 6.6 26.9 12 6.0 26.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DivIC PF04977.15 CDJ43649.1 - 7.9 6.3 15.6 14 5.5 15.6 1.4 1 0 0 1 1 1 0 Septum formation initiator CCDC117 PF15810.5 CDJ43649.1 - 9.4 6.5 14.3 4.9 7.5 11.5 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 117 SR-25 PF10500.9 CDJ43650.1 - 0.13 11.9 14.3 0.24 11.0 14.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein KAR9 PF08580.10 CDJ43650.1 - 4.6 5.7 10.8 6.5 5.2 10.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 GTP1_OBG PF01018.22 CDJ43653.1 - 3.8e-17 62.3 0.5 8.1e-17 61.2 0.5 1.5 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 CDJ43653.1 - 1.5e-10 41.1 0.0 3.8e-10 39.9 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDJ43653.1 - 0.005 16.9 0.1 0.0098 16.0 0.1 1.5 1 1 0 1 1 1 1 Dynamin family DDHD PF02862.17 CDJ43653.1 - 0.019 15.1 0.7 0.027 14.6 0.7 1.3 1 0 0 1 1 1 0 DDHD domain GTP_EFTU PF00009.27 CDJ43653.1 - 0.086 12.4 0.5 4.2 6.9 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CDJ43653.1 - 0.1 13.1 4.5 0.28 11.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 CDJ43653.1 - 0.13 12.5 0.2 0.74 10.1 0.0 2.4 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase SpoIIP PF07454.11 CDJ43653.1 - 0.25 10.7 4.1 0.39 10.1 4.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AAA_23 PF13476.6 CDJ43653.1 - 0.99 9.9 17.0 29 5.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Neur_chan_memb PF02932.16 CDJ43653.1 - 1.4 8.9 5.2 2.2 8.3 5.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CDJ43653.1 - 1.5 8.8 9.3 0.92 9.4 7.3 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ43653.1 - 1.6 7.4 7.2 2.3 6.9 7.2 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ43653.1 - 2.4 8.1 4.9 4.2 7.3 4.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Roughex PF06020.11 CDJ43653.1 - 3.8 6.5 13.4 7 5.6 13.4 1.4 1 0 0 1 1 1 0 Drosophila roughex protein ThiF PF00899.21 CDJ43654.1 - 3.7e-21 75.6 0.0 4.1e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 CDJ43654.1 - 3.3e-10 40.3 0.0 5.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Macro PF01661.21 CDJ43656.1 - 1.1e-09 38.3 0.3 4.8e-09 36.3 0.0 2.1 2 1 1 3 3 3 1 Macro domain WD40 PF00400.32 CDJ43657.1 - 0.0019 19.0 0.0 0.0031 18.3 0.0 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat DUF4641 PF15483.6 CDJ43657.1 - 1.6 7.8 11.1 1.6 7.7 10.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4641) HBM PF16591.5 CDJ43659.1 - 0.036 13.5 0.1 0.043 13.2 0.1 1.1 1 0 0 1 1 1 0 Helical bimodular sensor domain TH1 PF04858.13 CDJ43660.1 - 0.0013 17.5 0.0 0.0041 15.8 0.0 1.6 1 1 1 2 2 2 1 TH1 protein TFIIA PF03153.13 CDJ43660.1 - 1.3 8.9 4.9 1.7 8.6 4.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ43660.1 - 9.1 6.9 13.3 19 5.9 13.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rotamase PF00639.21 CDJ43661.1 - 6.4e-19 68.7 2.9 1.3e-17 64.6 2.9 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CDJ43661.1 - 1.3e-16 61.1 0.5 3.5e-15 56.5 1.2 1.9 1 1 1 2 2 2 2 PPIC-type PPIASE domain Rotamase_2 PF13145.6 CDJ43661.1 - 5.9e-05 23.9 0.5 0.00019 22.3 0.5 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain zf-RING_9 PF13901.6 CDJ43661.1 - 0.031 14.2 0.6 0.036 14.1 0.6 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Spc7 PF08317.11 CDJ43661.1 - 0.054 12.4 7.8 0.07 12.0 7.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1043 PF06295.12 CDJ43661.1 - 0.098 12.7 10.0 0.12 12.3 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3450 PF11932.8 CDJ43661.1 - 0.13 11.5 13.1 0.19 11.0 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) OmpH PF03938.14 CDJ43661.1 - 0.16 12.3 12.7 0.2 12.0 12.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2120 PF09893.9 CDJ43661.1 - 0.18 11.9 0.0 0.24 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Exonuc_VII_L PF02601.15 CDJ43661.1 - 0.63 9.6 7.1 0.66 9.5 7.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit EMC3_TMCO1 PF01956.16 CDJ43661.1 - 0.66 9.7 3.4 0.8 9.4 3.4 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like KfrA_N PF11740.8 CDJ43661.1 - 1.1 9.9 13.5 1.8 9.3 13.5 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term TFIIA PF03153.13 CDJ43661.1 - 2.9 7.8 14.7 3.1 7.7 14.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Acylphosphatase PF00708.18 CDJ43662.1 - 3.8e-05 24.0 0.2 4.8e-05 23.7 0.2 1.2 1 0 0 1 1 1 1 Acylphosphatase SR-25 PF10500.9 CDJ43662.1 - 0.081 12.5 8.5 0.065 12.8 8.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Iso_dh PF00180.20 CDJ43664.1 - 2.6e-13 49.8 0.0 2.8e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Tubulin PF00091.25 CDJ43667.1 - 3.9e-27 95.7 0.0 1e-26 94.4 0.0 1.7 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain ACBP PF00887.19 CDJ43668.1 - 6.7e-27 93.5 2.1 7.4e-27 93.4 2.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein COX14 PF14880.6 CDJ43669.1 - 3e-08 33.4 0.6 4e-08 33.0 0.6 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c assembly SR-25 PF10500.9 CDJ43669.1 - 0.0059 16.2 16.0 0.0069 16.0 16.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4667 PF15700.5 CDJ43669.1 - 0.05 13.7 9.5 0.086 12.9 9.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4667) Herpes_pp85 PF04637.12 CDJ43669.1 - 4.8 5.5 6.5 5.1 5.4 6.5 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) YGGT PF02325.17 CDJ43672.1 - 0.00032 21.1 0.1 0.00036 20.9 0.1 1.1 1 0 0 1 1 1 1 YGGT family DUF2828 PF11443.8 CDJ43673.1 - 0.0012 17.0 9.1 0.0017 16.6 9.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) LTV PF04180.14 CDJ43673.1 - 0.0034 17.2 13.5 0.0056 16.5 13.5 1.3 1 0 0 1 1 1 1 Low temperature viability protein PTPRCAP PF15713.5 CDJ43673.1 - 0.0076 16.5 23.9 0.0076 16.5 23.9 2.2 2 0 0 2 2 1 1 Protein tyrosine phosphatase receptor type C-associated SAPS PF04499.15 CDJ43673.1 - 0.027 13.3 8.5 0.045 12.6 8.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PA26 PF04636.13 CDJ43673.1 - 0.051 12.5 6.3 0.076 11.9 6.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DDHD PF02862.17 CDJ43673.1 - 0.065 13.4 13.4 0.029 14.5 8.9 2.4 2 0 0 2 2 2 0 DDHD domain Lin-8 PF03353.15 CDJ43673.1 - 0.085 12.4 25.8 0.17 11.4 25.8 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4746 PF15928.5 CDJ43673.1 - 0.11 11.9 13.0 0.2 11.0 13.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Neur_chan_memb PF02932.16 CDJ43673.1 - 0.23 11.5 11.8 0.56 10.2 11.8 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MMR1 PF08505.10 CDJ43673.1 - 0.27 11.5 19.2 0.68 10.2 19.2 1.7 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein RR_TM4-6 PF06459.12 CDJ43673.1 - 0.35 10.7 24.1 0.03 14.1 19.3 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 CDJ43673.1 - 0.36 10.3 18.9 0.62 9.5 18.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CDJ43673.1 - 0.39 9.4 25.4 0.022 13.6 20.3 1.5 2 0 0 2 2 2 0 Presenilin Endostatin PF06482.11 CDJ43673.1 - 0.44 10.0 13.3 0.91 8.9 13.3 1.6 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Hid1 PF12722.7 CDJ43673.1 - 1 7.4 19.0 1.8 6.6 19.0 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 CDJ43673.1 - 1.2 8.3 8.2 2.2 7.4 8.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 CDJ43673.1 - 1.4 8.9 12.8 3.1 7.7 12.8 1.6 1 0 0 1 1 1 0 Protein Family FAM60A SID-1_RNA_chan PF13965.6 CDJ43673.1 - 1.4 7.2 5.2 1.9 6.8 5.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Otopetrin PF03189.13 CDJ43673.1 - 1.9 7.2 6.7 2.9 6.6 6.7 1.2 1 0 0 1 1 1 0 Otopetrin DUF2052 PF09747.9 CDJ43673.1 - 2.3 8.3 26.2 5.4 7.1 26.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SLC12 PF03522.15 CDJ43673.1 - 4.3 6.2 19.6 7.2 5.5 19.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 CDJ43673.1 - 4.4 5.5 23.5 6.8 4.9 23.5 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 CDJ43673.1 - 5.8 6.4 16.0 10 5.6 16.0 1.3 1 0 0 1 1 1 0 PPP4R2 MCM_bind PF09739.9 CDJ43673.1 - 5.8 5.2 17.8 8.7 4.7 17.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Ctr PF04145.15 CDJ43673.1 - 5.8 7.5 7.9 20 5.8 7.9 2.0 1 0 0 1 1 1 0 Ctr copper transporter family Peptidase_S64 PF08192.11 CDJ43673.1 - 6.1 5.2 21.0 11 4.3 21.0 1.4 1 0 0 1 1 1 0 Peptidase family S64 MAP7 PF05672.11 CDJ43673.1 - 6.7 6.4 46.9 0.15 11.8 40.0 1.7 2 0 0 2 2 1 0 MAP7 (E-MAP-115) family Smg8_Smg9 PF10220.9 CDJ43673.1 - 6.9 4.8 18.3 11 4.1 18.3 1.3 1 0 0 1 1 1 0 Smg8_Smg9 Apt1 PF10351.9 CDJ43673.1 - 8.3 5.1 19.0 13 4.5 19.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tim54 PF11711.8 CDJ43673.1 - 9.2 4.9 20.9 18 4.0 20.9 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S49_N PF08496.10 CDJ43674.1 - 1.1 9.3 7.5 9 6.3 0.1 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF572 PF04502.13 CDJ43674.1 - 3.3 7.3 13.7 4.3 6.9 13.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Roughex PF06020.11 CDJ43674.1 - 4 6.4 18.7 2.6 7.1 6.4 2.1 2 0 0 2 2 2 0 Drosophila roughex protein DUF1840 PF08895.11 CDJ43674.1 - 5.4 7.4 14.5 2.1 8.7 5.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) HBB PF06777.11 CDJ43676.1 - 2.3e-22 79.6 8.5 1.8e-14 53.9 0.0 3.5 2 1 0 3 3 3 3 Helical and beta-bridge domain DUF2722 PF10846.8 CDJ43676.1 - 0.0068 15.4 7.3 0.008 15.2 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Drf_GBD PF06371.13 CDJ43676.1 - 0.068 12.7 1.5 0.089 12.4 1.5 1.3 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain DUF4050 PF13259.6 CDJ43676.1 - 0.18 12.1 4.0 0.26 11.6 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Suf PF05843.14 CDJ43676.1 - 0.38 10.7 6.4 0.5 10.3 6.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Roughex PF06020.11 CDJ43676.1 - 0.5 9.4 10.0 0.74 8.9 10.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PIEZO PF15917.5 CDJ43676.1 - 0.79 9.2 9.3 1.2 8.6 9.3 1.2 1 0 0 1 1 1 0 Piezo CobT PF06213.12 CDJ43676.1 - 1.1 8.6 11.7 1.5 8.1 11.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Spt20 PF12090.8 CDJ43676.1 - 4.1 7.0 20.8 7.2 6.1 20.8 1.4 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ43676.1 - 4.9 8.2 8.8 8.2 7.5 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DDE_Tnp_ISAZ013 PF07592.11 CDJ43676.1 - 5.2 5.9 6.5 7.4 5.4 6.5 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain zf-RING_2 PF13639.6 CDJ43677.1 - 2.8e-12 46.7 4.4 4.3e-12 46.2 4.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CDJ43677.1 - 2.1e-09 37.5 7.5 1.4e-08 34.9 7.5 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CDJ43677.1 - 1.5e-08 34.3 4.0 3e-08 33.4 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ43677.1 - 5.4e-07 29.2 2.5 1.1e-06 28.3 2.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CDJ43677.1 - 1.4e-06 28.1 3.9 2.4e-06 27.3 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ43677.1 - 2.5e-06 27.4 3.7 8.2e-06 25.8 3.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ43677.1 - 9.7e-06 25.5 3.0 2.2e-05 24.3 3.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 CDJ43677.1 - 1.1e-05 25.4 2.8 2.7e-05 24.2 2.8 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 CDJ43677.1 - 1.2e-05 25.2 0.9 4.4e-05 23.4 0.9 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CDJ43677.1 - 0.0035 17.2 2.2 0.006 16.4 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CDJ43677.1 - 0.014 15.0 2.6 0.028 14.1 2.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 CDJ43677.1 - 0.035 13.9 0.2 0.068 13.0 0.2 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif PHD PF00628.29 CDJ43677.1 - 0.061 13.2 3.1 0.15 12.0 3.1 1.7 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 CDJ43677.1 - 0.071 12.9 1.1 0.15 11.9 1.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 CDJ43677.1 - 0.08 13.1 4.1 0.16 12.1 4.1 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 CDJ43677.1 - 0.19 11.7 2.0 3.2 7.8 0.5 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 CDJ43677.1 - 0.21 11.4 2.6 0.37 10.6 2.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain D123 PF07065.14 CDJ43677.1 - 1.6 7.8 10.5 0.082 12.0 0.6 2.4 2 0 0 2 2 2 0 D123 Prok-RING_4 PF14447.6 CDJ43677.1 - 2 8.3 5.5 11 6.0 5.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-P11 PF03854.14 CDJ43677.1 - 2.9 7.6 4.9 0.52 10.0 1.1 1.6 2 0 0 2 2 2 0 P-11 zinc finger Presenilin PF01080.17 CDJ43678.1 - 0.0018 17.1 10.8 0.0027 16.6 10.8 1.4 1 0 0 1 1 1 1 Presenilin DUF1631 PF07793.11 CDJ43678.1 - 0.0092 14.5 2.3 0.0092 14.5 2.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1631) Cortex-I_coil PF09304.10 CDJ43678.1 - 0.014 15.6 3.7 0.014 15.6 3.7 2.6 3 0 0 3 3 3 0 Cortexillin I, coiled coil FAM199X PF15814.5 CDJ43678.1 - 1.3 8.0 4.9 2.4 7.1 4.9 1.4 1 0 0 1 1 1 0 Protein family FAM199X PaaX_C PF08223.11 CDJ43678.1 - 5.3 7.4 11.2 0.083 13.2 3.0 2.2 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain Utp14 PF04615.13 CDJ43678.1 - 5.4 5.5 25.4 7.7 4.9 25.3 1.3 1 1 0 1 1 1 0 Utp14 protein Connexin PF00029.19 CDJ43678.1 - 9.9 5.8 11.7 12 5.6 3.7 2.3 2 0 0 2 2 2 0 Connexin HATPase_c PF02518.26 CDJ43679.1 - 7.4e-11 42.5 0.0 1.8e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDJ43679.1 - 0.0043 16.9 0.0 0.0043 16.9 0.0 2.8 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cys_rich_CPXG PF14255.6 CDJ43679.1 - 0.063 13.2 6.2 0.16 11.8 6.2 1.7 1 0 0 1 1 1 0 Cysteine-rich CPXCG FHIPEP PF00771.20 CDJ43679.1 - 0.11 11.0 1.0 0.16 10.4 1.0 1.2 1 0 0 1 1 1 0 FHIPEP family Ribosomal_60s PF00428.19 CDJ43679.1 - 2.3 8.9 49.7 0.18 12.4 6.3 5.0 6 0 0 6 6 6 0 60s Acidic ribosomal protein Presenilin PF01080.17 CDJ43680.1 - 4 6.1 32.8 4.3 6.0 32.8 1.0 1 0 0 1 1 1 0 Presenilin Cwf_Cwc_15 PF04889.12 CDJ43680.1 - 6.2 6.5 30.5 7 6.3 30.5 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PCMT PF01135.19 CDJ43681.1 - 1.5e-24 87.0 0.0 5.9e-20 71.9 0.0 2.0 1 1 1 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NAP PF00956.18 CDJ43682.1 - 6.7e-10 38.6 3.3 1.2e-05 24.6 0.0 2.1 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Tmemb_cc2 PF10267.9 CDJ43682.1 - 0.0011 18.2 3.7 0.0013 17.9 3.7 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein SR-25 PF10500.9 CDJ43682.1 - 0.0033 17.1 0.9 0.0038 16.9 0.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF229 PF02995.17 CDJ43682.1 - 0.023 13.3 0.0 0.029 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF4407 PF14362.6 CDJ43682.1 - 0.068 12.5 0.2 0.075 12.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IMUP PF15761.5 CDJ43682.1 - 0.47 11.2 6.9 0.16 12.7 3.9 1.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein ORC_WH_C PF18137.1 CDJ43683.1 - 0.047 13.8 5.6 0.069 13.2 5.6 1.2 1 1 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF3340 PF11818.8 CDJ43683.1 - 0.62 10.2 13.4 1 9.5 2.6 2.2 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) DUF3276 PF11680.8 CDJ43683.1 - 0.8 9.8 8.5 1.1 9.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) Rsc14 PF08586.10 CDJ43683.1 - 1.2 9.9 10.2 3.7 8.4 1.2 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit ANAPC_CDC26 PF10471.9 CDJ43683.1 - 1.9 9.4 28.8 0.15 12.9 9.8 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 MPM1 PF17234.2 CDJ43683.1 - 6.4 7.0 16.8 0.6 10.4 5.5 2.0 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF4199 PF13858.6 CDJ43683.1 - 7.9 6.8 11.7 0.39 11.1 4.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) DAGK_acc PF00609.19 CDJ43684.1 - 1.9e-24 86.8 0.0 1.7e-12 48.0 0.0 2.3 2 0 0 2 2 2 2 Diacylglycerol kinase accessory domain Ycf4 PF02392.16 CDJ43684.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.6 2 0 0 2 2 2 1 Ycf4 Dehydrin PF00257.19 CDJ43684.1 - 0.11 13.1 1.6 0.16 12.5 1.6 1.4 1 0 0 1 1 1 0 Dehydrin LSM PF01423.22 CDJ43686.1 - 2.3e-16 59.2 0.0 3.7e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain TFIIA PF03153.13 CDJ43686.1 - 0.0017 18.5 7.4 0.0019 18.3 7.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ43686.1 - 0.0053 16.4 12.3 0.0073 16.0 12.3 1.2 1 0 0 1 1 1 1 Spt20 family DUF4820 PF16091.5 CDJ43686.1 - 0.0079 15.6 1.0 0.014 14.8 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) SM-ATX PF14438.6 CDJ43686.1 - 0.035 14.2 0.3 0.081 13.1 0.0 1.7 2 0 0 2 2 2 0 Ataxin 2 SM domain eIF-3_zeta PF05091.12 CDJ43686.1 - 0.19 10.6 4.1 0.25 10.3 4.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ43686.1 - 0.35 11.9 2.0 0.55 11.2 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2828 PF11443.8 CDJ43688.1 - 0.083 11.0 7.1 0.077 11.1 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 CDJ43688.1 - 2 7.1 13.1 2.5 6.8 13.1 1.2 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CDJ43688.1 - 9.1 4.1 12.0 9.2 4.0 12.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PWI PF01480.17 CDJ43689.1 - 3.4e-14 52.9 1.2 8.4e-14 51.7 0.3 2.0 2 0 0 2 2 2 1 PWI domain PAP1 PF08601.10 CDJ43689.1 - 0.0061 16.3 10.2 0.0078 16.0 10.2 1.2 1 0 0 1 1 1 1 Transcription factor PAP1 RAP1 PF07218.11 CDJ43689.1 - 0.012 13.9 7.1 0.014 13.7 7.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 CDJ43689.1 - 0.052 12.1 15.6 0.064 11.8 15.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF1677 PF07911.13 CDJ43689.1 - 0.06 13.7 0.3 0.06 13.7 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1677) Ndc1_Nup PF09531.10 CDJ43689.1 - 0.09 11.5 8.0 0.094 11.4 8.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PNISR PF15996.5 CDJ43689.1 - 1.1 9.6 24.6 1.4 9.2 24.6 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Menin PF05053.13 CDJ43689.1 - 1.9 6.7 10.8 2.4 6.4 10.8 1.2 1 0 0 1 1 1 0 Menin Apt1 PF10351.9 CDJ43689.1 - 2.1 7.1 20.4 3.1 6.6 20.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain PI3K_1B_p101 PF10486.9 CDJ43689.1 - 3 5.5 14.6 3.5 5.3 14.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GREB1 PF15782.5 CDJ43689.1 - 4.3 4.3 15.2 5.1 4.1 15.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MCPVI PF02993.14 CDJ43692.1 - 0.018 14.9 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 Minor capsid protein VI MAP65_ASE1 PF03999.12 CDJ43693.1 - 0.91 8.1 23.2 1.2 7.8 23.2 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Ras PF00071.22 CDJ43694.1 - 4.2e-46 156.5 0.0 5.1e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ43694.1 - 1.8e-29 102.4 0.0 2.7e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ43694.1 - 3.6e-14 52.6 0.0 4.8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ43694.1 - 3.9e-06 26.9 0.0 6.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ43694.1 - 6.4e-06 25.7 0.0 9.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDJ43694.1 - 8.5e-05 22.2 0.0 0.00034 20.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ43694.1 - 0.0018 18.2 0.0 0.38 10.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Apt1 PF10351.9 CDJ43694.1 - 0.0036 16.2 1.6 0.0042 16.0 1.6 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain NACHT PF05729.12 CDJ43694.1 - 0.061 13.3 0.0 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Menin PF05053.13 CDJ43694.1 - 0.066 11.6 1.0 0.089 11.1 1.0 1.1 1 0 0 1 1 1 0 Menin SPX PF03105.19 CDJ43694.1 - 1.2 9.0 9.5 1.5 8.7 9.5 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 CDJ43694.1 - 1.8 7.1 11.1 2.4 6.6 11.1 1.1 1 0 0 1 1 1 0 Macoilin family CCDC24 PF15669.5 CDJ43694.1 - 3.9 7.3 7.3 5.8 6.7 7.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Ribosomal_60s PF00428.19 CDJ43695.1 - 1 10.0 0.1 1 10.0 0.1 6.0 4 1 2 6 6 6 0 60s Acidic ribosomal protein FapA PF03961.13 CDJ43695.1 - 4.4 5.8 11.2 7.2 5.1 11.2 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Stk19 PF10494.9 CDJ43696.1 - 2.4e-07 30.7 0.1 5.8e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 JAB PF01398.21 CDJ43697.1 - 8.7e-08 32.2 0.1 1.2e-07 31.8 0.1 1.1 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DnaJ PF00226.31 CDJ43699.1 - 6.8e-06 26.1 0.1 1.2e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain ANAPC_CDC26 PF10471.9 CDJ43699.1 - 0.00047 20.9 7.4 0.00092 20.0 7.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Treacle PF03546.14 CDJ43699.1 - 0.0062 15.4 2.8 0.0078 15.1 2.8 1.0 1 0 0 1 1 1 1 Treacher Collins syndrome protein Treacle Pex26 PF07163.12 CDJ43699.1 - 0.036 13.4 3.4 0.052 12.9 3.4 1.2 1 0 0 1 1 1 0 Pex26 protein Roughex PF06020.11 CDJ43699.1 - 0.064 12.3 2.5 0.088 11.9 2.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF5423 PF17461.2 CDJ43699.1 - 6.9 5.4 8.7 8.8 5.1 8.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) WD40 PF00400.32 CDJ43700.1 - 2.4e-07 31.3 3.5 0.0007 20.4 0.1 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat Nup160 PF11715.8 CDJ43700.1 - 0.00076 18.2 1.6 0.026 13.2 0.2 2.8 2 1 1 3 3 3 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CDJ43700.1 - 0.0029 17.9 0.0 4.7 7.6 0.0 3.2 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PBP1_TM PF14812.6 CDJ43700.1 - 0.1 13.0 1.1 0.19 12.1 1.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_60s PF00428.19 CDJ43700.1 - 1 10.0 27.6 0.57 10.8 7.5 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein RNA_pol_Rpc4 PF05132.14 CDJ43700.1 - 2.3 8.6 5.3 0.95 9.9 1.9 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Secretin_N_2 PF07655.13 CDJ43700.1 - 6.9 7.3 16.7 0.27 11.8 7.0 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain COG6 PF06419.11 CDJ43701.1 - 0.003 15.8 1.2 0.003 15.8 1.2 4.0 4 1 0 4 4 4 3 Conserved oligomeric complex COG6 NOG1 PF06858.14 CDJ43701.1 - 0.023 14.5 0.2 0.27 11.1 0.2 2.7 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) OATP PF03137.20 CDJ43701.1 - 0.61 8.3 1.8 2 6.6 0.1 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3533 PF12051.8 CDJ43701.1 - 2.2 7.1 8.0 0.29 10.0 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) CA_like PF10563.9 CDJ43701.1 - 3.2 7.6 6.7 1.3 8.9 0.7 2.5 2 0 0 2 2 2 0 Putative carbonic anhydrase CwsA PF10814.8 CDJ43702.1 - 0.032 14.4 0.7 0.06 13.5 0.7 1.6 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Glyco_hydro_32C PF08244.12 CDJ43702.1 - 0.065 13.2 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal DUF3138 PF11336.8 CDJ43702.1 - 0.66 8.5 3.7 0.99 7.9 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Arf PF00025.21 CDJ43703.1 - 3e-40 137.5 0.0 3.7e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CDJ43703.1 - 6.6e-09 35.4 0.2 2.9e-06 26.7 0.1 2.0 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CDJ43703.1 - 9.6e-08 31.7 0.0 1.1e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDJ43703.1 - 6.8e-07 29.4 0.0 8.6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CDJ43703.1 - 7.2e-07 29.4 0.0 1.9e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ43703.1 - 0.00011 21.9 0.0 0.00014 21.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CDJ43703.1 - 0.0007 19.0 0.0 0.00087 18.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 CDJ43703.1 - 0.094 12.5 0.0 0.19 11.5 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 CDJ43703.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain PRR18 PF15671.5 CDJ43706.1 - 0.0087 16.0 1.5 0.014 15.3 1.5 1.3 1 0 0 1 1 1 1 Proline-rich protein family 18 SSP160 PF06933.11 CDJ43706.1 - 0.71 8.0 7.0 0.96 7.6 7.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Spt20 PF12090.8 CDJ43706.1 - 1.2 8.7 15.5 2.1 7.9 1.1 2.3 2 0 0 2 2 2 0 Spt20 family PPP4R2 PF09184.11 CDJ43706.1 - 1.3 8.6 5.3 0.27 10.8 1.4 1.8 2 0 0 2 2 2 0 PPP4R2 PSD4 PF07631.11 CDJ43706.1 - 5.9 7.4 9.5 7.8 7.1 1.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1592) DUF667 PF05018.13 CDJ43707.1 - 8.5e-59 198.4 0.0 1e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Dopey_N PF04118.14 CDJ43708.1 - 0.036 13.2 0.3 0.052 12.7 0.3 1.2 1 0 0 1 1 1 0 Dopey, N-terminal RskA PF10099.9 CDJ43709.1 - 0.11 12.8 0.1 0.11 12.8 0.1 4.5 2 2 1 3 3 3 0 Anti-sigma-K factor rskA DUF3602 PF12223.8 CDJ43709.1 - 4.3 8.0 9.2 8.8 7.0 0.3 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) SR-25 PF10500.9 CDJ43710.1 - 5.9e-06 26.1 7.7 1.3e-05 24.9 7.7 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Utp21 PF04192.12 CDJ43710.1 - 0.014 14.9 4.2 0.026 14.0 4.2 1.4 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain CCSAP PF15748.5 CDJ43710.1 - 0.24 11.6 18.4 0.025 14.8 10.0 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated BNIP3 PF06553.12 CDJ43710.1 - 0.76 9.4 11.9 1.4 8.5 11.9 1.4 1 0 0 1 1 1 0 BNIP3 Suf PF05843.14 CDJ43710.1 - 4.3 7.2 12.2 0.17 11.8 5.6 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DDHD PF02862.17 CDJ43710.1 - 7.7 6.6 11.1 0.68 10.1 5.2 2.0 2 0 0 2 2 2 0 DDHD domain DUF4834 PF16118.5 CDJ43711.1 - 1e-05 26.4 8.0 7.2e-05 23.7 0.2 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4834) DUF5327 PF17261.2 CDJ43711.1 - 0.0042 17.8 16.3 0.68 10.7 8.4 3.5 3 0 0 3 3 3 2 Family of unknown function (DUF5327) TERB2 PF15101.6 CDJ43711.1 - 0.012 15.7 8.6 0.012 15.7 8.6 2.9 3 0 0 3 3 3 0 Telomere-associated protein TERB2 PAP2 PF01569.21 CDJ43711.1 - 0.033 14.0 1.0 0.2 11.4 1.0 2.4 1 1 0 1 1 1 0 PAP2 superfamily Connexin PF00029.19 CDJ43711.1 - 0.041 13.6 0.6 0.041 13.6 0.6 2.2 2 1 1 3 3 3 0 Connexin TRAP_alpha PF03896.16 CDJ43711.1 - 0.08 12.1 0.5 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CLN3 PF02487.17 CDJ43711.1 - 0.082 11.9 3.9 0.068 12.2 0.7 2.1 2 0 0 2 2 2 0 CLN3 protein DUF1980 PF09323.10 CDJ43711.1 - 0.14 12.1 4.5 0.22 11.4 0.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) YfhO PF09586.10 CDJ43711.1 - 0.15 10.3 1.8 0.29 9.3 1.3 1.6 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Folate_carrier PF01770.18 CDJ43711.1 - 0.21 10.3 3.2 0.3 9.8 0.3 2.1 2 0 0 2 2 2 0 Reduced folate carrier SID-1_RNA_chan PF13965.6 CDJ43711.1 - 0.26 9.7 0.0 0.5 8.7 0.0 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FAM76 PF16046.5 CDJ43711.1 - 0.32 10.3 13.1 0.13 11.6 5.1 2.8 3 0 0 3 3 3 0 FAM76 protein MDM10 PF12519.8 CDJ43711.1 - 0.71 8.7 7.2 1.1 8.0 7.2 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Comm PF15957.5 CDJ43711.1 - 0.8 10.1 0.0 0.8 10.1 0.0 2.4 4 0 0 4 4 3 0 Commissureless GREB1 PF15782.5 CDJ43711.1 - 0.82 6.7 9.7 1.1 6.2 9.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer OATP PF03137.20 CDJ43711.1 - 1.3 7.3 2.5 1.3 7.2 0.4 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RIC3 PF15361.6 CDJ43711.1 - 1.3 9.4 7.9 0.57 10.6 0.8 2.8 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 Peroxin-13_N PF04088.13 CDJ43711.1 - 4.8 7.5 8.5 0.3 11.4 0.4 2.8 3 1 0 3 3 3 0 Peroxin 13, N-terminal region V_ATPase_I PF01496.19 CDJ43711.1 - 6 4.7 13.1 0.047 11.6 4.2 1.8 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family DUF4746 PF15928.5 CDJ43711.1 - 6.9 6.0 8.2 10 5.4 4.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Herpes_DNAp_acc PF04929.12 CDJ43711.1 - 8 5.3 9.6 15 4.4 9.6 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MPM1 PF17234.2 CDJ43711.1 - 8.8 6.6 18.6 0.19 11.9 6.2 2.9 3 0 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 Peptidase_S49_N PF08496.10 CDJ43712.1 - 0.028 14.5 1.6 0.031 14.3 1.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2722 PF10846.8 CDJ43712.1 - 0.031 13.2 15.2 0.029 13.3 15.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Apc15p PF05841.11 CDJ43712.1 - 0.059 14.2 8.1 0.069 14.0 8.1 1.1 1 0 0 1 1 1 0 Apc15p protein NARP1 PF12569.8 CDJ43712.1 - 0.12 11.2 5.7 0.13 11.2 5.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Folliculin PF11704.8 CDJ43712.1 - 0.14 12.1 3.3 0.13 12.1 3.3 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Presenilin PF01080.17 CDJ43712.1 - 0.71 8.6 4.5 0.65 8.7 4.5 1.1 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 CDJ43712.1 - 0.75 10.2 3.7 1 9.7 3.7 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3464 PF11947.8 CDJ43712.1 - 0.91 9.3 4.0 1 9.1 4.0 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TFIIA PF03153.13 CDJ43712.1 - 1.2 9.1 23.5 1.3 8.9 23.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EIIBC-GUT_N PF03612.14 CDJ43712.1 - 2 8.1 5.3 2.6 7.8 5.3 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Suf PF05843.14 CDJ43712.1 - 2.2 8.2 9.1 2.3 8.1 9.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) 60KD_IMP PF02096.20 CDJ43712.1 - 3.3 7.6 8.4 4.3 7.2 8.4 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein PepSY_TM PF03929.16 CDJ43712.1 - 3.3 7.3 4.7 3.4 7.2 4.7 1.1 1 0 0 1 1 1 0 PepSY-associated TM region DUF4199 PF13858.6 CDJ43712.1 - 3.6 8.0 3.6 4.1 7.8 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF4175 PF13779.6 CDJ43712.1 - 4.1 5.2 19.8 4.7 5.0 19.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Neur_chan_memb PF02932.16 CDJ43712.1 - 4.8 7.2 6.4 5.3 7.0 6.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0560 PF10577.9 CDJ43712.1 - 5.8 5.3 12.0 5.6 5.3 12.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 adh_short_C2 PF13561.6 CDJ43713.1 - 1.6e-11 44.2 0.0 3.1e-05 23.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ43713.1 - 0.0096 15.4 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase RCC1 PF00415.18 CDJ43715.1 - 9.6e-06 26.1 5.1 0.011 16.4 0.0 3.3 3 1 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ43715.1 - 3.1e-05 23.6 1.2 0.0004 20.1 0.3 2.7 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat Phage_lysozyme PF00959.19 CDJ43715.1 - 0.092 13.2 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Phage lysozyme AAA_lid_3 PF17862.1 CDJ43716.1 - 9.3e-10 38.2 0.1 1.4e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CDJ43716.1 - 4.4e-07 30.4 0.1 4.8e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Clathrin PF00637.20 CDJ43716.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Region in Clathrin and VPS TAF4 PF05236.14 CDJ43717.1 - 3.6 7.2 6.7 5.4 6.7 6.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family AP2 PF00847.20 CDJ43720.1 - 4e-13 49.4 17.8 4.2e-09 36.5 3.0 4.9 5 0 0 5 5 5 3 AP2 domain TFIIA PF03153.13 CDJ43720.1 - 0.00041 20.5 13.9 0.00057 20.0 13.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ43720.1 - 4 6.1 5.0 5.1 5.7 5.0 1.2 1 0 0 1 1 1 0 Presenilin CBM_48 PF02922.18 CDJ43721.1 - 5.8e-11 42.6 0.0 6.2e-09 36.1 0.0 2.9 2 1 1 3 3 3 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CDJ43721.1 - 3.2e-07 30.2 0.0 4.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain AMPK1_CBM PF16561.5 CDJ43721.1 - 0.057 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase B9-C2 PF07162.11 CDJ43723.1 - 1.3e-05 25.4 0.1 1.7e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF3292 PF11696.8 CDJ43724.1 - 1 7.6 0.0 1 7.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) Prp31_C PF09785.9 CDJ43725.1 - 8.8e-24 84.7 6.9 7.7e-21 75.2 6.9 2.5 1 1 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.18 CDJ43725.1 - 3.2e-05 23.5 0.1 6.5e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin DUF3180 PF11377.8 CDJ43726.1 - 0.14 12.3 8.9 0.19 11.9 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) Lin-8 PF03353.15 CDJ43726.1 - 3.9 6.9 5.8 4.2 6.8 5.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ43726.1 - 8.8 6.2 17.3 9.9 6.0 17.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAN_4 PF14295.6 CDJ43727.1 - 1.2e-24 85.9 47.2 1.3e-05 25.0 1.7 7.6 7 0 0 7 7 7 7 PAN domain PAN_1 PF00024.26 CDJ43727.1 - 6.3e-23 80.6 37.2 1.6e-07 31.2 0.2 7.9 6 2 2 8 8 8 7 PAN domain PAN_2 PF08276.11 CDJ43727.1 - 0.22 11.7 38.7 3.8 7.7 1.2 7.5 7 0 0 7 7 7 0 PAN-like domain Sporozoite_P67 PF05642.11 CDJ43727.1 - 2.8 5.9 6.2 4.8 5.1 6.2 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FSA_C PF10479.9 CDJ43727.1 - 3.3 5.7 8.9 4.7 5.2 8.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus MANEC PF07502.14 CDJ43727.1 - 7.3 6.9 32.4 4.2 7.7 0.1 7.0 6 1 0 7 7 7 0 MANEC domain SUIM_assoc PF16619.5 CDJ43728.1 - 0.0025 17.8 3.6 0.0043 17.1 3.6 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 CENP-F_leu_zip PF10473.9 CDJ43729.1 - 0.0082 16.2 7.4 0.0082 16.2 7.4 4.7 4 1 0 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SR-25 PF10500.9 CDJ43729.1 - 0.011 15.3 19.3 0.011 15.3 19.3 5.6 3 1 1 4 4 4 0 Nuclear RNA-splicing-associated protein Pentapeptide_4 PF13599.6 CDJ43730.1 - 0.27 11.4 2.6 1.8 8.8 0.8 2.1 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) Pex14_N PF04695.13 CDJ43731.1 - 0.02 15.6 6.0 0.02 15.6 6.0 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PIP5K PF01504.18 CDJ43731.1 - 0.11 11.7 0.2 0.18 11.0 0.2 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase MMR1 PF08505.10 CDJ43731.1 - 3.5 7.8 14.3 0.47 10.7 5.3 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein RHH_8 PF17723.1 CDJ43731.1 - 6 7.1 9.2 13 6.0 0.9 2.5 2 1 0 2 2 2 0 Ribbon-Helix-Helix transcriptional regulator family zf-RING_11 PF17123.5 CDJ43734.1 - 5.5e-06 26.0 3.3 8.8e-06 25.4 3.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CDJ43734.1 - 9.7e-06 25.5 0.1 1.5e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDJ43734.1 - 1.5e-05 25.2 0.6 2.2e-05 24.7 0.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ43734.1 - 4.4e-05 23.3 0.5 6.3e-05 22.8 0.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ43734.1 - 6e-05 22.8 0.7 9.5e-05 22.2 0.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ43734.1 - 0.017 15.1 2.2 0.14 12.2 2.8 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.6 CDJ43734.1 - 0.017 15.3 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDJ43734.1 - 0.078 13.2 0.1 0.091 13.0 0.1 1.2 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-rbx1 PF12678.7 CDJ43734.1 - 0.1 12.9 5.8 1 9.7 5.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 CDJ43734.1 - 0.32 10.7 2.0 0.58 9.8 2.0 1.4 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ribosomal_60s PF00428.19 CDJ43734.1 - 5.3 7.7 11.1 11 6.7 11.1 1.6 1 1 0 1 1 1 0 60s Acidic ribosomal protein ADH_zinc_N PF00107.26 CDJ43735.1 - 0.057 13.4 0.0 0.06 13.3 0.0 1.0 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Utp14 PF04615.13 CDJ43736.1 - 3.4e-32 111.9 0.3 3.9e-32 111.8 0.3 1.0 1 0 0 1 1 1 1 Utp14 protein Ribosomal_60s PF00428.19 CDJ43736.1 - 3.4 8.3 14.4 7.3 7.3 14.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.25 CDJ43737.1 - 3.3e-40 138.1 0.0 4.1e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ43737.1 - 2.5e-20 72.9 0.0 3.1e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ43737.1 - 9.3e-08 31.7 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ43737.1 - 0.0028 17.0 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ43737.1 - 0.0066 15.3 0.0 0.0089 14.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CDJ43737.1 - 0.0091 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ43737.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CDJ43737.1 - 0.024 13.7 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 ECH_1 PF00378.20 CDJ43738.1 - 1.3e-31 109.9 2.6 2.5e-25 89.2 3.5 2.3 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDJ43738.1 - 7.7e-11 42.1 0.6 8.2e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Porin_5 PF16930.5 CDJ43738.1 - 1.5 7.2 6.1 2.6 6.4 6.1 1.3 1 0 0 1 1 1 0 Putative porin SUIM_assoc PF16619.5 CDJ43738.1 - 6.6 6.9 9.6 0.38 10.8 3.8 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 EGF_CA PF07645.15 CDJ43740.1 - 1.3e-38 130.9 53.5 2.3e-10 40.5 3.6 7.4 6 1 1 7 7 7 6 Calcium-binding EGF domain cEGF PF12662.7 CDJ43740.1 - 9.7e-27 92.6 31.6 2.2e-08 33.9 1.4 7.1 6 0 0 6 6 6 5 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CDJ43740.1 - 4.8e-16 58.7 67.0 2.7e-06 27.5 8.1 6.6 7 0 0 7 7 7 5 Coagulation Factor Xa inhibitory site EGF PF00008.27 CDJ43740.1 - 2.2e-10 40.6 55.7 0.00054 20.2 0.3 7.1 5 1 2 7 7 6 5 EGF-like domain EGF_3 PF12947.7 CDJ43740.1 - 1.5e-07 31.5 37.2 0.019 15.2 0.3 6.2 6 0 0 6 6 6 5 EGF domain hEGF PF12661.7 CDJ43740.1 - 1.1e-05 25.8 63.3 0.0059 17.2 0.8 8.8 10 0 0 10 10 10 4 Human growth factor-like EGF RskA PF10099.9 CDJ43740.1 - 0.056 13.7 8.1 3.3 8.0 0.0 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA EGF_MSP1_1 PF12946.7 CDJ43740.1 - 0.066 13.3 31.4 1.5 8.9 1.4 5.8 6 0 0 6 6 6 0 MSP1 EGF domain 1 DUF2722 PF10846.8 CDJ43740.1 - 0.29 10.1 8.2 0.26 10.2 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Caudo_TAP PF02413.17 CDJ43740.1 - 0.57 10.3 9.0 3.3 7.9 1.4 2.2 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK ANAPC_CDC26 PF10471.9 CDJ43740.1 - 1.3 9.9 20.6 3.5 8.5 4.6 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 EF_TS PF00889.19 CDJ43742.1 - 2e-22 79.8 14.2 9.8e-20 71.0 1.8 3.2 3 1 0 3 3 3 2 Elongation factor TS SR-25 PF10500.9 CDJ43742.1 - 0.0094 15.6 12.7 0.0094 15.6 12.7 3.0 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein RHH_1 PF01402.21 CDJ43742.1 - 0.068 13.1 0.1 1.7 8.7 0.1 2.8 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family DUF4667 PF15700.5 CDJ43742.1 - 0.088 12.9 16.1 0.047 13.8 7.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) DUF5519 PF17648.1 CDJ43742.1 - 0.34 10.8 3.4 1 9.2 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5519) AF-4 PF05110.13 CDJ43742.1 - 3.7 5.5 24.7 0.023 12.8 12.5 2.3 2 0 0 2 2 2 0 AF-4 proto-oncoprotein LSM14 PF12701.7 CDJ43743.1 - 7.4e-27 93.3 0.0 9.4e-27 92.9 0.0 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 CDJ43743.1 - 7e-06 26.1 0.0 1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Dehydrin PF00257.19 CDJ43745.1 - 4.7 7.7 15.7 6.9 7.2 15.7 1.3 1 0 0 1 1 1 0 Dehydrin FlxA PF14282.6 CDJ43746.1 - 0.045 13.8 0.7 0.045 13.8 0.7 5.6 5 1 0 5 5 5 0 FlxA-like protein BBS2_C PF14782.6 CDJ43747.1 - 0.0062 15.3 1.7 0.0073 15.1 1.7 1.0 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal Spt20 PF12090.8 CDJ43747.1 - 0.015 14.9 18.7 0.015 14.9 18.7 1.0 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ43747.1 - 0.094 13.7 2.7 0.12 13.3 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Connexin PF00029.19 CDJ43747.1 - 0.12 12.1 0.1 0.14 11.9 0.1 1.0 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDJ43747.1 - 0.29 9.8 4.3 0.29 9.8 4.3 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ43747.1 - 0.65 8.2 10.9 0.69 8.1 10.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3138 PF11336.8 CDJ43747.1 - 1.3 7.6 7.2 1.5 7.4 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TFIIA PF03153.13 CDJ43747.1 - 2.6 7.9 20.0 2.9 7.8 20.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 CDJ43747.1 - 3.8 6.1 7.8 4.3 5.9 7.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Androgen_recep PF02166.16 CDJ43747.1 - 6.7 5.4 21.6 9.1 5.0 21.6 1.2 1 0 0 1 1 1 0 Androgen receptor Lipoprotein_9 PF03180.14 CDJ43749.1 - 3.4e-98 327.5 4.7 3.9e-98 327.3 4.7 1.0 1 0 0 1 1 1 1 NLPA lipoprotein OpuAC PF04069.12 CDJ43749.1 - 0.00016 21.4 1.5 0.00033 20.3 1.5 1.8 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1 PF09084.11 CDJ43749.1 - 0.0025 17.8 0.1 0.025 14.5 0.1 2.1 1 1 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 CDJ43749.1 - 0.0074 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein LPAM_2 PF13627.6 CDJ43749.1 - 0.81 9.6 5.4 1.4 8.8 5.4 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Exonuc_VII_L PF02601.15 CDJ43751.1 - 0.00013 21.7 20.3 0.00013 21.7 20.3 2.0 2 1 0 2 2 2 1 Exonuclease VII, large subunit Presenilin PF01080.17 CDJ43751.1 - 0.012 14.4 34.0 0.032 13.0 32.7 2.0 2 0 0 2 2 2 0 Presenilin AAA_11 PF13086.6 CDJ43751.1 - 0.06 13.1 21.6 0.15 11.9 21.6 1.7 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 CDJ43751.1 - 0.12 10.7 24.5 0.2 9.9 24.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4045 PF13254.6 CDJ43751.1 - 0.26 10.9 29.8 0.56 9.8 23.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) SPX PF03105.19 CDJ43751.1 - 0.27 11.1 24.2 0.42 10.5 20.5 2.2 2 0 0 2 2 2 0 SPX domain Caldesmon PF02029.15 CDJ43751.1 - 0.4 9.4 26.4 0.64 8.7 26.4 1.3 1 0 0 1 1 1 0 Caldesmon Dapper PF15268.6 CDJ43751.1 - 0.62 8.9 35.5 0.15 10.9 31.3 1.8 2 0 0 2 2 2 0 Dapper SLC12 PF03522.15 CDJ43751.1 - 0.76 8.7 34.1 0.43 9.6 31.8 1.6 2 0 0 2 2 2 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ43751.1 - 0.83 9.4 30.6 0.05 13.4 25.4 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 CDJ43751.1 - 1.9 7.6 23.6 1.4 8.1 21.4 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Suf PF05843.14 CDJ43751.1 - 2.4 8.1 42.4 0.068 13.1 32.5 2.6 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) SOBP PF15279.6 CDJ43751.1 - 2.7 8.5 35.4 2.5 8.6 26.3 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein Asp-B-Hydro_N PF05279.11 CDJ43751.1 - 2.7 8.0 18.6 4.2 7.4 18.6 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CCSAP PF15748.5 CDJ43751.1 - 4.9 7.3 37.4 0.44 10.7 29.5 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated HSP70 PF00012.20 CDJ43751.1 - 6.7 4.8 22.0 9.7 4.2 22.0 1.1 1 0 0 1 1 1 0 Hsp70 protein Peroxin-3 PF04882.12 CDJ43751.1 - 8.2 5.3 31.3 2.6 6.9 26.2 2.2 2 0 0 2 2 2 0 Peroxin-3 Apt1 PF10351.9 CDJ43751.1 - 8.4 5.1 23.5 7.4 5.3 20.4 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Catalase PF00199.19 CDJ43752.1 - 1.1e-105 353.9 0.0 1.5e-105 353.5 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CDJ43752.1 - 2e-10 40.7 0.0 4.4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive PPR_3 PF13812.6 CDJ43753.1 - 0.075 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Pentatricopeptide repeat domain Chalcone_2 PF16035.5 CDJ43753.1 - 0.61 9.8 5.8 0.88 9.3 4.3 1.9 2 0 0 2 2 2 0 Chalcone isomerase like DUF5320 PF17253.2 CDJ43753.1 - 2.9 9.0 5.3 9.5 7.4 5.3 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Ephrin_rec_like PF07699.13 CDJ43755.1 - 6.6e-05 22.6 9.5 0.0016 18.1 0.6 6.8 4 2 3 7 7 7 4 Putative ephrin-receptor like TFIIA PF03153.13 CDJ43755.1 - 0.022 14.8 13.5 0.029 14.4 13.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ43755.1 - 0.6 8.8 1.9 0.78 8.4 1.9 1.1 1 0 0 1 1 1 0 Presenilin TNFR_c6 PF00020.18 CDJ43755.1 - 1.2 9.5 0.1 1.2 9.5 0.1 6.7 4 2 3 7 7 7 0 TNFR/NGFR cysteine-rich region Pex14_N PF04695.13 CDJ43755.1 - 2 9.1 10.4 3.2 8.4 10.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ43755.1 - 3 7.8 10.2 4.2 7.3 10.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4407 PF14362.6 CDJ43755.1 - 4.9 6.4 6.4 7.1 5.9 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Corona_nucleoca PF00937.18 CDJ43756.1 - 0.00023 20.3 7.3 0.00026 20.1 7.3 1.0 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein SR-25 PF10500.9 CDJ43756.1 - 0.0032 17.1 9.0 0.0046 16.6 9.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TMEM51 PF15345.6 CDJ43756.1 - 0.036 13.9 1.7 0.045 13.6 1.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 CcmD PF04995.14 CDJ43756.1 - 0.56 10.3 7.0 0.89 9.7 7.0 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Presenilin PF01080.17 CDJ43756.1 - 0.62 8.8 4.5 0.73 8.5 4.5 1.1 1 0 0 1 1 1 0 Presenilin EphA2_TM PF14575.6 CDJ43756.1 - 2.1 9.3 5.2 0.58 11.1 0.8 1.9 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF5421 PF17458.2 CDJ43756.1 - 2.9 7.2 8.1 1.4 8.2 6.3 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5421) IMUP PF15761.5 CDJ43757.1 - 0.064 14.0 0.1 0.082 13.6 0.1 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein zf-CCHC_3 PF13917.6 CDJ43758.1 - 1.1e-17 63.7 4.1 1.1e-17 63.7 4.1 1.9 2 0 0 2 2 2 1 Zinc knuckle AF-4 PF05110.13 CDJ43758.1 - 0.00021 19.6 26.6 0.00021 19.6 26.6 3.4 2 1 1 3 3 3 1 AF-4 proto-oncoprotein IMUP PF15761.5 CDJ43758.1 - 0.00021 21.9 15.8 0.00021 21.9 15.8 5.9 3 1 1 4 4 4 1 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ43758.1 - 0.0038 16.9 36.6 0.0038 16.9 36.6 4.7 2 2 1 3 3 3 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ43758.1 - 3.2 8.0 27.6 0.44 10.8 19.9 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA NnrS PF05940.12 CDJ43759.1 - 0.002 17.6 0.8 0.0032 16.9 0.8 1.3 1 0 0 1 1 1 1 NnrS protein DUF3138 PF11336.8 CDJ43759.1 - 9.4 4.7 12.6 19 3.7 12.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MFS_1 PF07690.16 CDJ43760.1 - 1.7e-11 43.7 5.7 1.7e-11 43.7 5.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CDJ43760.1 - 0.032 12.5 0.1 0.032 12.5 0.1 3.1 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family NAM-associated PF14303.6 CDJ43760.1 - 0.054 14.2 0.0 0.054 14.2 0.0 2.8 1 1 2 3 3 3 0 No apical meristem-associated C-terminal domain Sugar_tr PF00083.24 CDJ43760.1 - 0.076 11.9 1.9 0.1 11.4 1.9 1.4 1 1 0 1 1 1 0 Sugar (and other) transporter DUF2890 PF11081.8 CDJ43760.1 - 0.94 9.6 12.1 0.19 11.8 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Ribosomal_S14 PF00253.21 CDJ43761.1 - 4.5e-17 61.5 0.5 6.4e-17 61.1 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Usher_TcfC PF17271.2 CDJ43761.1 - 0.15 10.8 0.5 0.2 10.4 0.5 1.1 1 0 0 1 1 1 0 TcfC Usher-like barrel domain EF-hand_7 PF13499.6 CDJ43762.1 - 4.8e-13 49.3 0.2 1.8e-09 37.9 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ43762.1 - 1.4e-09 37.6 0.2 5.3e-09 35.8 0.2 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ43762.1 - 4.4e-08 32.1 0.1 0.0075 15.7 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CDJ43762.1 - 1.9e-06 27.3 0.2 0.027 14.4 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_11 PF08976.11 CDJ43762.1 - 0.0013 19.5 0.0 0.011 16.6 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain MSP1_C PF07462.11 CDJ43762.1 - 7.5 5.1 7.6 10 4.7 7.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pkinase PF00069.25 CDJ43763.1 - 0.00015 21.3 0.0 0.00015 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CBM53 PF16760.5 CDJ43764.1 - 0.00072 20.1 0.0 0.0015 19.1 0.0 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) IMUP PF15761.5 CDJ43764.1 - 0.042 14.5 3.1 0.042 14.5 3.1 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein S6PP PF05116.13 CDJ43764.1 - 0.092 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Herpes_pp85 PF04637.12 CDJ43764.1 - 0.64 8.4 1.7 0.98 7.8 1.7 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3446 PF11928.8 CDJ43764.1 - 1.2 9.5 13.1 0.27 11.6 5.8 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF2722 PF10846.8 CDJ43765.1 - 0.0026 16.8 14.0 0.0026 16.8 14.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ43765.1 - 0.0026 17.4 30.7 0.016 14.8 22.4 2.2 2 0 0 2 2 2 2 Spt20 family EPL1 PF10513.9 CDJ43765.1 - 0.0075 16.7 4.0 0.02 15.3 1.3 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like Pex14_N PF04695.13 CDJ43765.1 - 0.015 16.0 9.1 0.015 16.0 9.1 2.8 2 1 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FPN1 PF06963.12 CDJ43765.1 - 0.039 12.5 0.3 0.064 11.8 0.3 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) BORG_CEP PF14957.6 CDJ43765.1 - 0.13 13.4 3.7 0.66 11.1 0.5 2.3 2 0 0 2 2 2 0 Cdc42 effector DUF913 PF06025.12 CDJ43765.1 - 0.22 10.5 3.4 0.21 10.5 0.5 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) TFIIA PF03153.13 CDJ43765.1 - 0.3 11.1 41.3 0.6 10.0 41.4 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 CDJ43765.1 - 1 9.3 4.1 0.69 9.9 2.2 1.6 2 0 0 2 2 2 0 Protein Family FAM60A DUF4834 PF16118.5 CDJ43765.1 - 1.2 10.1 11.2 1.8 9.6 6.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SpoIIP PF07454.11 CDJ43765.1 - 2.9 7.3 8.9 0.34 10.3 4.4 1.7 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) TERB2 PF15101.6 CDJ43765.1 - 2.9 7.9 12.1 0.29 11.2 6.0 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Senescence_reg PF04520.13 CDJ43765.1 - 4.1 8.2 11.3 4.9 8.0 3.6 2.4 2 0 0 2 2 2 0 Senescence regulator CPSF100_C PF13299.6 CDJ43765.1 - 4.2 7.5 12.6 0.4 10.8 5.6 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4770 PF15994.5 CDJ43765.1 - 7 6.8 11.7 0.44 10.8 6.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Ras PF00071.22 CDJ43767.1 - 2.6e-25 88.9 0.0 3.1e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ43767.1 - 2.5e-21 76.1 0.0 2.9e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ43767.1 - 8.5e-07 28.6 0.0 9.6e-07 28.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ43767.1 - 0.0016 18.5 0.0 0.0021 18.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ43767.1 - 0.051 12.9 0.0 0.065 12.6 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 CDJ43767.1 - 0.19 11.1 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein FAT PF02259.23 CDJ43768.1 - 4.1e-15 55.9 0.5 4.1e-15 55.9 0.5 2.0 2 0 0 2 2 2 1 FAT domain HSP70 PF00012.20 CDJ43769.1 - 2e-22 79.2 0.9 4.3e-21 74.8 0.0 2.2 1 1 0 2 2 2 1 Hsp70 protein Pex14_N PF04695.13 CDJ43769.1 - 0.0019 18.8 2.3 0.0035 18.0 2.3 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.10 CDJ43769.1 - 0.0031 16.3 11.9 0.0038 16.0 11.9 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.8 CDJ43769.1 - 0.0068 15.4 12.8 0.0087 15.1 12.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RLL PF10036.9 CDJ43769.1 - 0.016 15.1 1.9 0.016 15.1 1.9 1.8 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein DUF5421 PF17458.2 CDJ43769.1 - 0.02 14.3 4.0 0.027 13.9 4.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) EOS1 PF12326.8 CDJ43769.1 - 0.022 14.7 0.1 0.031 14.2 0.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein Pal1 PF08316.11 CDJ43769.1 - 0.026 15.3 0.1 0.042 14.6 0.1 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein FHIPEP PF00771.20 CDJ43769.1 - 0.032 12.7 1.2 0.043 12.3 1.2 1.2 1 0 0 1 1 1 0 FHIPEP family DUF4834 PF16118.5 CDJ43769.1 - 0.046 14.7 3.1 0.084 13.9 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ43769.1 - 0.083 12.9 3.5 0.12 12.3 3.5 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4064 PF13273.6 CDJ43769.1 - 0.09 13.1 0.1 0.21 11.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Presenilin PF01080.17 CDJ43769.1 - 0.14 10.9 0.3 0.13 11.0 0.3 1.1 1 0 0 1 1 1 0 Presenilin CagX PF03524.15 CDJ43769.1 - 0.18 11.5 3.0 0.4 10.4 2.4 1.7 2 0 0 2 2 2 0 Conjugal transfer protein UPF0560 PF10577.9 CDJ43769.1 - 0.37 9.2 7.4 0.51 8.8 7.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Activator_LAG-3 PF11498.8 CDJ43769.1 - 0.63 9.0 22.8 0.9 8.4 22.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.8 CDJ43769.1 - 0.63 9.6 23.7 1.1 8.8 23.7 1.3 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ43769.1 - 1.5 7.8 6.8 2.2 7.3 6.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Med3 PF11593.8 CDJ43769.1 - 2.1 7.4 14.5 0.26 10.5 10.5 1.6 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ43769.1 - 3.1 8.0 21.2 5.2 7.3 20.6 1.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ43769.1 - 3.1 8.3 5.7 2.6 8.6 0.3 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4179) DivIC PF04977.15 CDJ43769.1 - 6 6.7 13.0 12 5.8 13.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF2076 PF09849.9 CDJ43769.1 - 6.5 6.7 23.9 1.7 8.6 20.8 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) SID-1_RNA_chan PF13965.6 CDJ43770.1 - 0.026 12.9 1.5 0.029 12.8 1.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DcuA_DcuB PF03605.14 CDJ43770.1 - 0.056 12.3 13.0 0.065 12.1 13.0 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Connexin PF00029.19 CDJ43770.1 - 0.084 12.6 6.9 0.098 12.4 6.9 1.1 1 0 0 1 1 1 0 Connexin Activator_LAG-3 PF11498.8 CDJ43770.1 - 0.089 11.8 27.0 0.11 11.4 27.0 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 eIF-3_zeta PF05091.12 CDJ43770.1 - 0.11 11.5 15.0 0.1 11.6 15.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1980 PF09323.10 CDJ43770.1 - 0.13 12.2 5.6 0.14 12.0 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) FAM199X PF15814.5 CDJ43770.1 - 0.14 11.2 16.9 0.18 10.8 16.9 1.3 1 0 0 1 1 1 0 Protein family FAM199X Spem1 PF15670.5 CDJ43770.1 - 0.17 11.5 8.2 0.19 11.3 8.2 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF1168 PF06658.12 CDJ43770.1 - 0.19 11.5 19.5 0.34 10.7 19.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Miga PF10265.9 CDJ43770.1 - 0.32 9.9 8.4 0.4 9.6 8.4 1.1 1 0 0 1 1 1 0 Mitoguardin NEMP PF10225.9 CDJ43770.1 - 0.5 10.0 2.8 0.59 9.7 2.8 1.1 1 0 0 1 1 1 0 NEMP family Peptidase_S49_N PF08496.10 CDJ43770.1 - 0.5 10.4 11.2 0.67 10.0 11.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Serinc PF03348.15 CDJ43770.1 - 0.69 8.8 8.7 0.77 8.6 8.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.12 CDJ43770.1 - 0.78 9.5 11.6 0.72 9.6 11.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ctr PF04145.15 CDJ43770.1 - 0.78 10.3 4.7 1.1 9.9 4.7 1.2 1 0 0 1 1 1 0 Ctr copper transporter family OATP PF03137.20 CDJ43770.1 - 0.94 7.7 2.7 1 7.6 2.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF1682 PF07946.14 CDJ43770.1 - 1.1 8.4 13.5 1.2 8.2 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Presenilin PF01080.17 CDJ43770.1 - 1.2 7.8 14.7 1.2 7.8 14.7 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ43770.1 - 1.3 9.0 7.3 1.2 9.1 7.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TERB2 PF15101.6 CDJ43770.1 - 1.6 8.7 14.4 1.7 8.6 14.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EOS1 PF12326.8 CDJ43770.1 - 1.7 8.5 4.5 2.1 8.2 4.5 1.3 1 0 0 1 1 1 0 N-glycosylation protein CSG2 PF16965.5 CDJ43770.1 - 1.8 7.4 3.0 1.9 7.4 3.0 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DDHD PF02862.17 CDJ43770.1 - 2 8.5 10.3 2.2 8.4 10.3 1.1 1 0 0 1 1 1 0 DDHD domain FHIPEP PF00771.20 CDJ43770.1 - 2.2 6.7 12.2 2.8 6.3 12.2 1.1 1 0 0 1 1 1 0 FHIPEP family MAJIN PF15077.6 CDJ43770.1 - 2.3 7.9 8.2 2.3 7.9 8.2 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein TFIIA PF03153.13 CDJ43770.1 - 4.6 7.1 37.3 4.9 7.0 37.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FancD2 PF14631.6 CDJ43770.1 - 4.9 4.4 10.8 5.4 4.3 10.8 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Tic110 PF16940.5 CDJ43770.1 - 5.5 5.4 19.0 6.8 5.1 19.0 1.3 1 0 0 1 1 1 0 Chloroplast envelope transporter DUF913 PF06025.12 CDJ43770.1 - 6.1 5.7 8.9 6.5 5.6 8.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) V_ATPase_I PF01496.19 CDJ43770.1 - 6.7 4.5 12.0 7 4.4 12.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rrn6 PF10214.9 CDJ43770.1 - 9 4.6 16.0 9.5 4.6 16.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF5585 PF17823.1 CDJ43770.1 - 9.1 5.1 21.4 10 4.9 21.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5585) RskA PF10099.9 CDJ43771.1 - 0.0087 16.4 13.4 0.0087 16.4 13.4 3.1 2 1 0 2 2 2 1 Anti-sigma-K factor rskA Glyco_hydro_9 PF00759.19 CDJ43771.1 - 0.13 11.6 7.2 0.044 13.2 1.4 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 DinB PF05163.12 CDJ43771.1 - 0.49 10.3 3.7 0.2 11.6 0.3 2.1 2 0 0 2 2 2 0 DinB family SR-25 PF10500.9 CDJ43771.1 - 0.52 9.9 12.5 2.2 7.8 1.7 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HflK_N PF12221.8 CDJ43772.1 - 0.0007 19.5 0.4 0.00081 19.3 0.4 1.2 1 0 0 1 1 1 1 Bacterial membrane protein N terminal DUF4130 PF13566.6 CDJ43772.1 - 0.038 14.0 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 Ldh_1_C PF02866.18 CDJ43772.1 - 0.089 12.7 0.5 0.11 12.5 0.5 1.1 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Spt20 PF12090.8 CDJ43772.1 - 0.53 9.8 6.9 0.54 9.8 6.9 1.1 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ43772.1 - 1.1 8.0 9.4 1.2 7.9 9.4 1.0 1 0 0 1 1 1 0 Androgen receptor DUF2967 PF11179.8 CDJ43772.1 - 3.6 5.6 4.1 3.3 5.7 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) MKT1_C PF12246.8 CDJ43773.1 - 2.1e-35 122.1 0.0 3.1e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication PH_5 PF15405.6 CDJ43775.1 - 0.96 9.6 8.0 20 5.3 0.1 2.9 1 1 1 2 2 2 0 Pleckstrin homology domain XRN_N PF03159.18 CDJ43776.1 - 3.5e-22 79.0 12.7 2.6e-20 72.9 12.7 2.9 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Spore_coat_CotO PF14153.6 CDJ43776.1 - 0.0022 18.0 15.2 0.0027 17.7 15.2 1.2 1 0 0 1 1 1 1 Spore coat protein CotO Neur_chan_memb PF02932.16 CDJ43776.1 - 0.0026 17.9 4.3 0.0029 17.7 4.3 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ43776.1 - 0.0056 16.7 29.1 0.0062 16.6 29.1 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ43776.1 - 0.0076 15.7 5.8 0.0089 15.5 5.8 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) MCM_bind PF09739.9 CDJ43776.1 - 0.033 12.6 6.8 0.036 12.5 6.8 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SOG2 PF10428.9 CDJ43776.1 - 0.038 13.2 8.5 0.042 13.1 8.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Raftlin PF15250.6 CDJ43776.1 - 0.067 11.9 9.1 0.075 11.8 9.1 1.1 1 0 0 1 1 1 0 Raftlin SUV3_C PF12513.8 CDJ43776.1 - 0.069 13.1 0.5 0.17 11.8 0.1 1.8 2 0 0 2 2 1 0 Mitochondrial degradasome RNA helicase subunit C terminal Ndc1_Nup PF09531.10 CDJ43776.1 - 0.073 11.8 7.4 0.077 11.7 7.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spc7_N PF15402.6 CDJ43776.1 - 0.094 11.0 14.9 0.1 10.8 14.9 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 NPR3 PF03666.13 CDJ43776.1 - 0.12 11.2 10.2 0.13 11.0 10.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pex14_N PF04695.13 CDJ43776.1 - 0.13 13.0 22.6 0.19 12.3 22.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.22 CDJ43776.1 - 0.13 11.5 6.1 0.14 11.3 6.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 CDJ43776.1 - 0.14 11.2 6.9 0.16 10.9 6.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CDJ43776.1 - 0.16 10.7 15.7 0.18 10.5 15.7 1.1 1 0 0 1 1 1 0 Presenilin Gti1_Pac2 PF09729.9 CDJ43776.1 - 0.16 12.1 6.8 0.22 11.6 6.8 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family PAT1 PF09770.9 CDJ43776.1 - 0.22 9.8 17.5 0.22 9.7 17.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ43776.1 - 0.22 8.6 14.6 0.25 8.4 14.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hydin_ADK PF17213.3 CDJ43776.1 - 0.23 11.7 9.0 0.3 11.4 9.0 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CDC45 PF02724.14 CDJ43776.1 - 0.31 9.3 10.4 0.37 9.0 10.4 1.0 1 0 0 1 1 1 0 CDC45-like protein CCSAP PF15748.5 CDJ43776.1 - 0.38 10.9 16.4 0.44 10.7 16.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Velvet PF11754.8 CDJ43776.1 - 0.44 10.4 15.0 0.58 10.1 15.0 1.1 1 0 0 1 1 1 0 Velvet factor Lin-8 PF03353.15 CDJ43776.1 - 0.45 10.0 15.9 0.54 9.8 15.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Connexin PF00029.19 CDJ43776.1 - 0.53 10.0 4.3 0.74 9.5 4.3 1.3 1 0 0 1 1 1 0 Connexin DUF4746 PF15928.5 CDJ43776.1 - 0.55 9.6 8.1 0.68 9.3 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FAM60A PF15396.6 CDJ43776.1 - 0.69 9.9 10.3 0.93 9.5 10.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A STAC2_u1 PF16664.5 CDJ43776.1 - 0.91 10.0 15.6 1.3 9.5 15.6 1.2 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 MAJIN PF15077.6 CDJ43776.1 - 0.96 9.2 9.2 1.2 8.9 9.2 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein ARF7EP_C PF14949.6 CDJ43776.1 - 1.1 10.0 15.3 3.5 8.3 15.3 1.8 1 1 0 1 1 1 0 ARF7 effector protein C-terminus Band_3_cyto PF07565.13 CDJ43776.1 - 1.1 9.0 8.4 1.3 8.7 8.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SLC12 PF03522.15 CDJ43776.1 - 1.5 7.7 11.8 1.8 7.5 11.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ43776.1 - 1.5 8.5 15.8 2.1 8.1 15.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 CDJ43776.1 - 2.1 7.8 8.5 3 7.3 8.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Dicty_REP PF05086.12 CDJ43776.1 - 2.3 6.1 7.1 2.6 5.9 7.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CobT PF06213.12 CDJ43776.1 - 2.4 7.5 24.0 3.7 6.9 24.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CBP_BcsG PF11658.8 CDJ43776.1 - 2.7 6.3 7.7 3.2 6.0 7.7 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Apt1 PF10351.9 CDJ43776.1 - 3 6.6 10.5 3.6 6.4 10.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PIP5K PF01504.18 CDJ43776.1 - 3.1 6.9 9.0 4.3 6.5 9.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase FancD2 PF14631.6 CDJ43776.1 - 3.2 5.0 9.3 3.8 4.8 9.3 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Peroxin-3 PF04882.12 CDJ43776.1 - 3.8 6.4 16.5 4.3 6.2 16.5 1.0 1 0 0 1 1 1 0 Peroxin-3 V_ATPase_I PF01496.19 CDJ43776.1 - 3.8 5.3 10.4 4.5 5.1 10.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L37 PF08561.10 CDJ43776.1 - 4 8.0 12.3 5.6 7.5 12.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 Peptidase_S64 PF08192.11 CDJ43776.1 - 4.3 5.7 11.5 4.8 5.6 11.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF2828 PF11443.8 CDJ43776.1 - 4.5 5.2 10.6 5.6 4.9 10.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Tsg PF04668.12 CDJ43776.1 - 4.8 7.9 12.7 11 6.7 10.1 2.0 1 1 1 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region GET2 PF08690.10 CDJ43776.1 - 4.9 6.7 17.3 6 6.4 17.3 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Baculo_PP31 PF05311.11 CDJ43776.1 - 5 6.5 9.5 7.2 6.0 9.5 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Tim54 PF11711.8 CDJ43776.1 - 5.6 5.7 11.8 7.9 5.2 11.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Otopetrin PF03189.13 CDJ43776.1 - 7 5.3 7.0 9.2 5.0 7.0 1.2 1 0 0 1 1 1 0 Otopetrin Hid1 PF12722.7 CDJ43776.1 - 7.2 4.6 16.1 9 4.3 16.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF5427 PF10310.9 CDJ43776.1 - 7.9 5.3 20.1 9.9 5.0 20.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) eIF-3_zeta PF05091.12 CDJ43776.1 - 8.4 5.2 15.8 11 4.9 15.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2126 PF09899.9 CDJ43777.1 - 1 7.3 7.5 1.1 7.3 7.5 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) FHIPEP PF00771.20 CDJ43777.1 - 1.3 7.4 7.0 1.4 7.3 7.0 1.0 1 0 0 1 1 1 0 FHIPEP family DUF1980 PF09323.10 CDJ43777.1 - 1.4 8.8 5.0 1.5 8.7 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PepSY_TM PF03929.16 CDJ43777.1 - 1.8 8.1 7.7 1.9 8.1 7.7 1.0 1 0 0 1 1 1 0 PepSY-associated TM region Pex14_N PF04695.13 CDJ43777.1 - 2.6 8.7 21.9 2.7 8.6 21.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF702 PF05142.12 CDJ43777.1 - 3.4 8.1 17.3 3.9 7.9 17.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Sec62 PF03839.16 CDJ43777.1 - 4.7 6.7 11.0 5 6.6 11.0 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 CPSF100_C PF13299.6 CDJ43777.1 - 5.9 7.0 10.7 6.2 7.0 10.7 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal EOS1 PF12326.8 CDJ43777.1 - 6.2 6.7 5.7 7.5 6.4 5.7 1.1 1 0 0 1 1 1 0 N-glycosylation protein DUF4834 PF16118.5 CDJ43777.1 - 7.2 7.6 12.1 10 7.2 12.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) eIF-3_zeta PF05091.12 CDJ43777.1 - 7.5 5.4 17.1 7.3 5.4 17.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 CDJ43777.1 - 8.7 6.2 34.9 9.1 6.2 34.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4770 PF15994.5 CDJ43777.1 - 9 6.5 16.9 10 6.3 16.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) SpoIIP PF07454.11 CDJ43777.1 - 9.5 5.6 12.8 10 5.4 12.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ADH_zinc_N PF00107.26 CDJ43778.1 - 3.3e-19 69.1 0.2 4.2e-19 68.8 0.2 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3446 PF11928.8 CDJ43780.1 - 0.02 15.2 2.9 0.02 15.2 2.9 3.6 3 1 1 4 4 4 0 Early growth response N-terminal domain DUF1645 PF07816.11 CDJ43780.1 - 0.023 15.3 19.8 0.049 14.2 10.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Radial_spoke_3 PF06098.11 CDJ43780.1 - 0.1 11.9 6.2 0.14 11.4 6.2 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 Spt20 PF12090.8 CDJ43780.1 - 0.18 11.4 7.0 0.3 10.7 7.0 1.3 1 0 0 1 1 1 0 Spt20 family MAP65_ASE1 PF03999.12 CDJ43780.1 - 0.22 10.2 6.8 0.4 9.3 6.8 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF966 PF06136.13 CDJ43780.1 - 0.56 9.9 10.5 0.93 9.1 10.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF966) Rrn6 PF10214.9 CDJ43780.1 - 1 7.8 14.8 1.2 7.5 14.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peptidase_S64 PF08192.11 CDJ43780.1 - 3.3 6.1 8.4 5.6 5.3 8.4 1.3 1 0 0 1 1 1 0 Peptidase family S64 SSP160 PF06933.11 CDJ43780.1 - 4.1 5.5 19.6 0.23 9.6 8.1 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 ETRAMP PF09716.10 CDJ43783.1 - 0.00011 22.2 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) RskA PF10099.9 CDJ43783.1 - 0.0012 19.1 16.0 0.0017 18.7 16.0 1.3 1 1 0 1 1 1 1 Anti-sigma-K factor rskA Trp_oprn_chp PF09534.10 CDJ43783.1 - 0.0031 17.4 2.7 0.0044 16.8 2.7 1.3 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4778 PF16008.5 CDJ43783.1 - 0.0046 17.1 4.2 0.005 16.9 4.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4778) AIM3 PF17096.5 CDJ43783.1 - 0.044 14.7 0.3 0.069 14.1 0.3 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DUF3824 PF12868.7 CDJ43783.1 - 0.075 13.7 14.0 0.12 13.1 14.0 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) TFIIA PF03153.13 CDJ43783.1 - 0.2 11.6 11.0 0.23 11.4 11.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 CDJ43783.1 - 0.37 9.9 8.2 0.4 9.8 8.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal eIF3_subunit PF08597.10 CDJ43783.1 - 0.38 10.6 7.5 0.47 10.3 7.5 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Spt20 PF12090.8 CDJ43783.1 - 0.48 10.0 7.0 0.61 9.6 7.0 1.3 1 0 0 1 1 1 0 Spt20 family EphA2_TM PF14575.6 CDJ43783.1 - 0.95 10.4 2.9 6.6 7.7 2.9 2.1 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MscS_TM PF12794.7 CDJ43783.1 - 2.2 7.1 14.0 0.67 8.8 10.5 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Presenilin PF01080.17 CDJ43783.1 - 5.9 5.6 4.5 6.8 5.3 4.5 1.1 1 0 0 1 1 1 0 Presenilin Baculo_PP31 PF05311.11 CDJ43783.1 - 7.8 5.9 5.8 10 5.5 5.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Androgen_recep PF02166.16 CDJ43785.1 - 4.3 6.1 15.5 4.1 6.1 15.5 1.0 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 CDJ43786.1 - 0.49 10.3 38.8 0.65 9.9 38.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sin_N PF04801.13 CDJ43786.1 - 0.9 8.7 26.9 0.96 8.6 26.9 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Presenilin PF01080.17 CDJ43786.1 - 1.2 7.8 18.9 1.4 7.6 18.9 1.1 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 CDJ43786.1 - 1.4 8.9 25.9 1.8 8.5 25.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ribonuc_P_40 PF08584.11 CDJ43786.1 - 1.7 7.9 10.9 2.1 7.6 10.9 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit RR_TM4-6 PF06459.12 CDJ43786.1 - 1.8 8.3 17.2 2 8.2 17.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ43786.1 - 3.2 7.7 12.6 4.4 7.2 12.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CLN3 PF02487.17 CDJ43786.1 - 4 6.4 6.8 5 6.1 6.8 1.2 1 0 0 1 1 1 0 CLN3 protein Zip PF02535.22 CDJ43786.1 - 4.2 6.5 9.7 5.2 6.2 9.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 CDJ43786.1 - 6 4.7 12.7 7.9 4.3 12.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 CDJ43786.1 - 6.2 5.7 15.5 7.4 5.5 15.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Connexin PF00029.19 CDJ43786.1 - 7.8 6.2 13.5 19 4.9 13.5 1.6 1 1 0 1 1 1 0 Connexin DNA_gyraseB_C PF00986.21 CDJ43787.1 - 6.4e-15 55.1 0.1 1.3e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus Toprim PF01751.22 CDJ43787.1 - 1.4e-08 34.9 0.1 7.7e-07 29.3 0.1 3.2 2 1 0 2 2 2 1 Toprim domain SR-25 PF10500.9 CDJ43787.1 - 0.002 17.8 3.8 0.002 17.8 3.8 1.8 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ43787.1 - 0.02 15.6 6.7 0.024 15.3 4.4 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein SUIM_assoc PF16619.5 CDJ43787.1 - 0.058 13.5 18.7 0.047 13.8 3.0 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF1635 PF07795.11 CDJ43787.1 - 0.1 12.5 8.1 0.23 11.3 8.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) BTB PF00651.31 CDJ43788.1 - 7.1e-05 23.0 0.1 0.00015 22.0 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF2722 PF10846.8 CDJ43788.1 - 0.0035 16.4 4.5 0.0035 16.4 4.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ43788.1 - 6.2 6.3 21.9 2.7 7.6 15.3 2.2 2 0 0 2 2 2 0 Spt20 family Miga PF10265.9 CDJ43790.1 - 0.56 9.1 19.6 0.77 8.7 19.6 1.3 1 0 0 1 1 1 0 Mitoguardin BNR_3 PF13859.6 CDJ43790.1 - 1.7 7.8 8.6 1.1 8.4 6.7 1.7 1 1 0 1 1 1 0 BNR repeat-like domain Dicty_REP PF05086.12 CDJ43790.1 - 5.6 4.8 7.7 7.6 4.4 7.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tic110 PF16940.5 CDJ43792.1 - 0.016 13.8 3.9 0.018 13.5 3.9 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter WD40 PF00400.32 CDJ43792.1 - 0.071 14.0 0.3 93 4.1 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat Shadoo PF14999.6 CDJ43792.1 - 0.26 11.4 8.0 0.48 10.5 8.0 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Adeno_PV PF03910.13 CDJ43792.1 - 4.4 5.9 5.5 2.2 6.9 3.6 1.4 2 0 0 2 2 2 0 Adenovirus minor core protein PV KRBA1 PF15287.6 CDJ43793.1 - 0.24 11.1 0.2 0.24 11.1 0.2 2.5 3 0 0 3 3 3 0 KRBA1 family repeat Myosin_head PF00063.21 CDJ43794.1 - 2.7e-71 240.7 0.0 3.6e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 CDJ43794.1 - 0.0032 17.7 0.1 0.0082 16.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CDJ43794.1 - 0.029 13.6 0.1 0.071 12.4 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 CDJ43794.1 - 0.09 13.2 1.7 0.26 11.7 1.7 2.1 1 1 0 1 1 1 0 AAA ATPase domain TPPK_C PF12555.8 CDJ43795.1 - 0.37 10.9 0.0 0.37 10.9 0.0 5.1 7 0 0 7 7 7 0 Thiamine pyrophosphokinase C terminal Connexin PF00029.19 CDJ43795.1 - 0.58 9.9 2.6 9.5 5.9 1.5 2.4 2 0 0 2 2 2 0 Connexin DUF3292 PF11696.8 CDJ43795.1 - 0.77 8.1 7.2 0.48 8.7 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) Hid1 PF12722.7 CDJ43795.1 - 9.3 4.2 10.4 16 3.5 10.4 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HSBP1 PF06825.12 CDJ43797.1 - 1.7e-11 43.8 2.2 2.3e-11 43.3 2.2 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 CDJ43797.1 - 0.0085 16.1 0.3 0.013 15.5 0.3 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3138 PF11336.8 CDJ43797.1 - 0.19 10.3 6.2 0.26 9.8 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) UPF0184 PF03670.13 CDJ43797.1 - 0.2 12.0 0.3 0.2 12.0 0.3 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Viral_P18 PF04521.13 CDJ43798.1 - 0.0066 16.2 0.3 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 ssRNA positive strand viral 18kD cysteine rich protein RskA PF10099.9 CDJ43798.1 - 1.3 9.3 16.4 3.3 8.0 16.4 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ43798.1 - 3 8.5 10.2 7.6 7.2 10.2 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein LSM PF01423.22 CDJ43799.1 - 3.3e-14 52.3 0.1 2.4e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 LSM domain Velvet PF11754.8 CDJ43799.1 - 0.0017 18.4 5.9 0.002 18.1 5.9 1.2 1 0 0 1 1 1 1 Velvet factor DUF5308 PF17233.2 CDJ43799.1 - 0.0029 17.8 4.7 0.0041 17.4 4.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5308) Spt20 PF12090.8 CDJ43799.1 - 0.0034 17.0 13.0 0.0047 16.6 13.0 1.4 1 0 0 1 1 1 1 Spt20 family SOG2 PF10428.9 CDJ43799.1 - 0.0055 16.0 6.3 0.0061 15.8 6.3 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein TFIIA PF03153.13 CDJ43799.1 - 0.028 14.4 17.8 0.032 14.3 17.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ43799.1 - 0.033 14.8 15.5 0.033 14.8 15.5 1.8 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ43799.1 - 0.061 13.3 7.3 0.066 13.2 7.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SMYLE_N PF18615.1 CDJ43799.1 - 0.22 11.0 5.4 0.29 10.7 5.4 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SARAF PF06682.12 CDJ43799.1 - 0.6 9.7 10.6 1.1 8.8 10.6 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2464 PF10240.9 CDJ43799.1 - 0.63 9.6 4.6 0.81 9.2 4.6 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 Ndc1_Nup PF09531.10 CDJ43799.1 - 0.76 8.4 6.3 0.87 8.2 6.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 CDJ43799.1 - 0.79 9.7 7.5 1 9.4 7.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ43799.1 - 0.95 8.2 9.2 1.1 8.0 9.2 1.1 1 0 0 1 1 1 0 Presenilin Spc7_N PF15402.6 CDJ43799.1 - 1.2 7.3 12.2 1.6 6.9 12.2 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Zip PF02535.22 CDJ43799.1 - 3.4 6.8 4.2 4 6.6 4.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 CDJ43799.1 - 4.6 6.6 12.8 6.9 6.0 12.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PAN_4 PF14295.6 CDJ43801.1 - 5.6e-20 71.0 13.5 2.4e-07 30.5 0.3 3.6 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 CDJ43801.1 - 3.7e-19 68.5 3.7 4e-06 26.7 0.1 3.4 2 1 0 3 3 3 3 PAN domain IMUP PF15761.5 CDJ43801.1 - 0.092 13.4 0.9 0.79 10.4 0.6 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein Med19 PF10278.9 CDJ43802.1 - 0.0016 18.4 5.0 0.0029 17.5 5.0 1.4 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 tRNA_anti-codon PF01336.25 CDJ43802.1 - 0.0019 18.2 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 CDJ43802.1 - 0.013 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Cgr1 PF03879.14 CDJ43802.1 - 1.1 9.7 27.1 2 8.8 20.1 2.4 2 0 0 2 2 2 0 Cgr1 family FAM199X PF15814.5 CDJ43802.1 - 1.5 7.8 19.0 0.065 12.3 13.1 1.7 2 0 0 2 2 2 0 Protein family FAM199X Serinc PF03348.15 CDJ43802.1 - 2.6 6.9 4.0 3.7 6.4 4.0 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Herpes_pp85 PF04637.12 CDJ43802.1 - 3.7 5.8 5.5 4.4 5.6 0.2 2.2 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Exonuc_VII_L PF02601.15 CDJ43802.1 - 3.8 7.0 17.2 3.2 7.2 8.7 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Spt20 PF12090.8 CDJ43802.1 - 4 7.0 31.8 1.3 8.5 15.9 2.2 2 0 0 2 2 2 0 Spt20 family DUF4770 PF15994.5 CDJ43802.1 - 5.6 7.2 15.4 11 6.2 7.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) MCD PF05292.11 CDJ43802.1 - 5.9 6.4 7.7 1.2 8.7 3.7 1.7 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain Neur_chan_memb PF02932.16 CDJ43802.1 - 9.3 6.2 12.3 15 5.6 12.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.10 CDJ43802.1 - 9.7 6.2 15.6 1.4 9.0 10.1 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Sec62 PF03839.16 CDJ43802.1 - 9.8 5.6 11.7 2 7.9 7.8 1.8 2 0 0 2 2 2 0 Translocation protein Sec62 V_ATPase_I PF01496.19 CDJ43803.1 - 0.21 9.4 13.1 0.26 9.2 13.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family VPS28 PF03997.12 CDJ43803.1 - 1.2 8.8 16.2 0.1 12.3 10.2 1.9 1 1 1 2 2 2 0 VPS28 protein DUF2730 PF10805.8 CDJ43803.1 - 1.9 8.6 22.0 0.64 10.1 11.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) LRR_8 PF13855.6 CDJ43806.1 - 6.7e-06 25.8 6.1 2.2e-05 24.1 5.7 2.1 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 CDJ43806.1 - 1.7e-05 25.0 2.8 0.0032 17.8 0.7 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) UPF0565 PF10561.9 CDJ43806.1 - 0.064 12.5 0.8 0.071 12.3 0.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 LRR_9 PF14580.6 CDJ43806.1 - 0.085 12.4 0.1 0.36 10.3 0.1 1.9 1 1 0 1 1 1 0 Leucine-rich repeat Presenilin PF01080.17 CDJ43806.1 - 0.17 10.6 0.7 0.2 10.4 0.7 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ43806.1 - 0.61 10.0 8.8 0.72 9.8 8.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ43807.1 - 0.071 12.7 23.3 0.11 12.1 23.4 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA PF00004.29 CDJ43808.1 - 3e-14 53.6 0.0 6.7e-14 52.5 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ43808.1 - 1.6e-12 48.1 0.0 2.8e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ43808.1 - 1.1e-07 32.2 0.0 3e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 CDJ43808.1 - 0.00021 21.2 0.0 0.001 19.0 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 CDJ43808.1 - 0.001 19.4 0.0 0.0052 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 CDJ43808.1 - 0.0063 16.5 0.0 0.0092 16.0 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 CDJ43808.1 - 0.0065 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 CDJ43808.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA lid domain AAA_7 PF12775.7 CDJ43808.1 - 0.015 14.9 0.1 0.028 13.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_32 PF13654.6 CDJ43808.1 - 0.019 13.8 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 CDJ43808.1 - 0.021 14.0 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Rad17 PF03215.15 CDJ43808.1 - 0.036 14.0 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 CDJ43808.1 - 0.038 13.7 0.1 0.062 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CDJ43808.1 - 0.047 13.9 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CDJ43808.1 - 0.062 13.2 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 CDJ43808.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 CDJ43808.1 - 0.13 12.2 0.0 0.55 10.1 0.0 2.1 3 0 0 3 3 3 0 NTPase DnaB_C PF03796.15 CDJ43808.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Viral_helicase1 PF01443.18 CDJ43808.1 - 0.17 11.6 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 CDJ43808.1 - 0.17 11.6 0.0 1.3 8.7 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Ku_N PF03731.15 CDJ43809.1 - 8e-07 29.0 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain CCB2_CCB4 PF11152.8 CDJ43809.1 - 0.0086 15.4 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 Pkinase PF00069.25 CDJ43811.1 - 3e-06 26.8 0.0 4.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ43811.1 - 0.00098 18.5 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_60s PF00428.19 CDJ43811.1 - 0.016 15.8 13.9 0.27 11.8 1.6 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3235 PF11574.8 CDJ43811.1 - 0.28 12.1 6.9 0.61 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) RNA_pol_Rpb5_C PF01191.19 CDJ43812.1 - 2.2e-34 117.2 0.3 3.2e-34 116.6 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Toprim_2 PF13155.6 CDJ43813.1 - 4.2e-08 33.5 0.0 1.7e-07 31.6 0.0 2.0 1 1 0 1 1 1 1 Toprim-like RskA PF10099.9 CDJ43813.1 - 8.1e-05 23.0 3.8 8.1e-05 23.0 3.8 2.7 3 0 0 3 3 3 1 Anti-sigma-K factor rskA Toprim_4 PF13662.6 CDJ43813.1 - 0.00045 20.6 0.0 0.00075 19.9 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 CDJ43813.1 - 0.0052 17.1 1.0 0.014 15.8 0.0 2.2 3 0 0 3 3 2 1 Toprim domain DEC-1_N PF04625.13 CDJ43813.1 - 0.0053 15.8 10.8 0.0053 15.8 10.8 1.9 1 1 1 2 2 2 1 DEC-1 protein, N-terminal region SUIM_assoc PF16619.5 CDJ43813.1 - 0.05 13.7 9.6 0.38 10.9 9.6 2.2 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Toprim PF01751.22 CDJ43813.1 - 0.11 12.7 0.0 0.43 10.8 0.0 1.9 1 1 0 1 1 1 0 Toprim domain Activator_LAG-3 PF11498.8 CDJ43813.1 - 0.35 9.8 14.7 0.64 8.9 14.7 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF2722 PF10846.8 CDJ43813.1 - 0.68 8.8 8.0 1 8.2 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) AF-4 PF05110.13 CDJ43813.1 - 2.9 5.9 10.0 0.62 8.1 2.6 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Spt20 PF12090.8 CDJ43813.1 - 5 6.7 13.5 7.8 6.0 13.5 1.2 1 0 0 1 1 1 0 Spt20 family Aminotran_5 PF00266.19 CDJ43814.1 - 0.012 14.6 1.5 0.13 11.2 0.2 2.5 2 0 0 2 2 2 0 Aminotransferase class-V Dfp1_Him1_M PF08630.10 CDJ43814.1 - 0.049 13.8 2.2 2 8.6 0.0 2.6 2 0 0 2 2 2 0 Dfp1/Him1, central region SprA-related PF12118.8 CDJ43814.1 - 0.32 10.1 42.7 0.025 13.8 17.9 3.5 3 0 0 3 3 3 0 SprA-related family PTPRCAP PF15713.5 CDJ43814.1 - 0.55 10.5 26.8 0.035 14.4 6.0 3.9 4 0 0 4 4 4 0 Protein tyrosine phosphatase receptor type C-associated Lin-8 PF03353.15 CDJ43814.1 - 0.72 9.4 29.4 0.17 11.4 10.9 2.8 2 1 1 3 3 3 0 Ras-mediated vulval-induction antagonist DUF2052 PF09747.9 CDJ43814.1 - 2.1 8.4 17.0 0.46 10.6 4.3 3.0 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Apt1 PF10351.9 CDJ43814.1 - 4.1 6.2 13.8 4.2 6.1 2.1 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Cpn60_TCP1 PF00118.24 CDJ43815.1 - 8.9e-72 242.3 0.1 1e-71 242.1 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_S8 PF00082.22 CDJ43816.1 - 2.4e-25 89.4 0.2 2.4e-25 89.4 0.2 1.7 2 0 0 2 2 2 1 Subtilase family PIEZO PF15917.5 CDJ43816.1 - 0.00022 20.8 1.1 0.00032 20.3 1.1 1.2 1 0 0 1 1 1 1 Piezo SID-1_RNA_chan PF13965.6 CDJ43816.1 - 0.016 13.7 0.0 0.02 13.3 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.10 CDJ43816.1 - 0.051 13.6 4.7 0.091 12.8 4.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Smac_DIABLO PF09057.10 CDJ43816.1 - 1.5 8.1 9.8 2.1 7.7 9.8 1.2 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases TMEM132D_C PF15706.5 CDJ43816.1 - 2.6 7.9 8.1 0.26 11.1 2.0 2.2 1 1 1 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4131 PF13567.6 CDJ43816.1 - 4.2 7.0 6.6 17 5.0 6.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) GYF PF02213.16 CDJ43818.1 - 7.8e-09 35.1 1.5 7.8e-09 35.1 1.5 1.7 2 0 0 2 2 2 1 GYF domain RskA PF10099.9 CDJ43818.1 - 1.9e-06 28.3 2.4 7.3e-06 26.4 0.1 2.0 1 1 1 2 2 2 1 Anti-sigma-K factor rskA DUF572 PF04502.13 CDJ43818.1 - 0.00094 18.9 7.0 0.0011 18.7 7.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) SR-25 PF10500.9 CDJ43818.1 - 0.0012 18.5 15.7 0.0026 17.4 15.6 1.6 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein CAF1 PF04857.20 CDJ43818.1 - 0.0042 16.3 3.0 0.0055 15.9 3.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease GYF_2 PF14237.6 CDJ43818.1 - 0.0098 15.7 0.2 0.025 14.4 0.2 1.8 1 0 0 1 1 1 1 GYF domain 2 DUF86 PF01934.17 CDJ43818.1 - 0.023 14.5 0.3 0.033 14.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF86 Macoilin PF09726.9 CDJ43818.1 - 0.4 9.2 11.2 0.56 8.7 11.2 1.2 1 0 0 1 1 1 0 Macoilin family EphA2_TM PF14575.6 CDJ43818.1 - 0.64 10.9 3.3 29 5.6 0.1 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Inj_translocase PF16928.5 CDJ43818.1 - 0.73 9.3 13.9 0.77 9.2 4.7 2.3 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome WRNPLPNID PF15017.6 CDJ43818.1 - 6.5 7.7 8.5 23 5.9 2.6 2.7 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box DUF2681 PF10883.8 CDJ43818.1 - 6.9 7.2 19.2 4.8 7.7 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) hDGE_amylase PF14701.6 CDJ43820.1 - 9.9e-43 146.8 0.0 1.3e-42 146.5 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain SUIM_assoc PF16619.5 CDJ43820.1 - 0.011 15.7 1.7 0.024 14.7 1.7 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Alpha-amylase PF00128.24 CDJ43820.1 - 0.18 11.3 0.0 0.88 9.1 0.0 1.9 2 0 0 2 2 2 0 Alpha amylase, catalytic domain PRMT5_TIM PF17285.2 CDJ43821.1 - 0.039 13.1 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 PRMT5 TIM barrel domain DUF755 PF05501.11 CDJ43823.1 - 0.01 16.1 11.8 0.01 16.1 11.8 6.1 5 1 0 5 5 5 0 Domain of unknown function (DUF755) DUF755 PF05501.11 CDJ43824.1 - 0.0017 18.6 22.9 0.0017 18.6 22.9 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF755) Macoilin PF09726.9 CDJ43824.1 - 0.0035 16.0 14.2 0.0042 15.7 14.2 1.2 1 0 0 1 1 1 1 Macoilin family SRP-alpha_N PF04086.13 CDJ43824.1 - 0.54 10.1 23.4 0.72 9.7 23.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF1645 PF07816.11 CDJ43824.1 - 0.58 10.7 22.4 0.074 13.6 9.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) CCDC24 PF15669.5 CDJ43824.1 - 9.8 6.0 22.1 0.076 12.9 8.4 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family Lin-8 PF03353.15 CDJ43824.1 - 9.9 5.6 26.9 0.65 9.5 12.0 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist RNase_PH PF01138.21 CDJ43826.1 - 6.3e-25 88.2 0.0 1e-24 87.5 0.0 1.3 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 SR-25 PF10500.9 CDJ43827.1 - 0.0019 17.9 3.2 0.0019 17.9 3.2 3.7 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ43827.1 - 0.02 15.2 5.7 0.02 15.2 5.7 3.7 4 0 0 4 4 4 0 Early growth response N-terminal domain TFIIA PF03153.13 CDJ43829.1 - 0.0077 16.3 14.1 0.0084 16.1 14.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SLC12 PF03522.15 CDJ43829.1 - 0.0082 15.2 0.5 0.0094 15.0 0.5 1.1 1 0 0 1 1 1 1 Solute carrier family 12 PAT1 PF09770.9 CDJ43829.1 - 0.035 12.4 7.8 0.036 12.4 7.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mucin PF01456.17 CDJ43829.1 - 0.06 13.3 0.9 0.16 12.0 0.9 1.9 1 1 0 1 1 1 0 Mucin-like glycoprotein MDM10 PF12519.8 CDJ43829.1 - 0.11 11.4 1.6 0.13 11.1 1.6 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Presenilin PF01080.17 CDJ43829.1 - 0.15 10.8 5.0 0.2 10.4 5.0 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 CDJ43829.1 - 0.48 10.1 3.0 0.74 9.5 3.0 1.2 1 0 0 1 1 1 0 Connexin RR_TM4-6 PF06459.12 CDJ43829.1 - 0.57 10.0 4.8 0.74 9.6 4.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4834 PF16118.5 CDJ43829.1 - 1.2 10.2 5.8 2 9.4 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SprA-related PF12118.8 CDJ43829.1 - 1.2 8.2 16.7 1.8 7.6 16.7 1.2 1 0 0 1 1 1 0 SprA-related family eIF-3_zeta PF05091.12 CDJ43829.1 - 1.3 8.0 8.7 1.6 7.6 8.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 CDJ43829.1 - 1.7 8.8 5.7 1.7 8.8 3.6 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EIIBC-GUT_N PF03612.14 CDJ43829.1 - 2.4 7.8 4.1 3.7 7.2 4.1 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus YfhO PF09586.10 CDJ43830.1 - 3.7e-05 22.2 0.2 4.2e-05 22.0 0.2 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO DUF4131 PF13567.6 CDJ43830.1 - 0.00035 20.3 6.0 0.00059 19.5 6.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Peptidase_S49_N PF08496.10 CDJ43830.1 - 0.0019 18.3 2.3 0.0048 17.0 2.3 1.7 1 0 0 1 1 1 1 Peptidase family S49 N-terminal BatD PF13584.6 CDJ43830.1 - 0.0079 15.1 0.4 0.74 8.6 0.3 2.7 1 1 1 2 2 2 1 Oxygen tolerance CBP_BcsG PF11658.8 CDJ43830.1 - 0.0091 14.4 0.2 0.0091 14.4 0.2 1.7 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsG FHIPEP PF00771.20 CDJ43830.1 - 0.0094 14.5 0.3 0.0094 14.5 0.3 1.4 2 0 0 2 2 2 1 FHIPEP family DUF3450 PF11932.8 CDJ43830.1 - 0.013 14.8 9.5 0.013 14.8 9.5 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF3450) FGF-BP1 PF06473.12 CDJ43830.1 - 0.017 14.9 2.7 0.017 14.9 2.7 2.2 3 0 0 3 3 2 0 FGF binding protein 1 (FGF-BP1) TMEM51 PF15345.6 CDJ43830.1 - 0.017 14.9 0.7 0.017 14.9 0.7 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 DUF2207 PF09972.9 CDJ43830.1 - 0.024 13.4 0.0 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5421 PF17458.2 CDJ43830.1 - 0.028 13.8 0.6 0.052 12.9 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5421) DUF4734 PF15881.5 CDJ43830.1 - 0.029 14.5 2.3 0.051 13.7 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4734) Spt20 PF12090.8 CDJ43830.1 - 0.036 13.7 14.1 0.055 13.1 14.1 1.2 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ43830.1 - 0.038 15.0 6.4 0.13 13.2 6.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) CLN3 PF02487.17 CDJ43830.1 - 0.055 12.5 0.1 0.086 11.9 0.1 1.3 1 0 0 1 1 1 0 CLN3 protein MecA PF05389.12 CDJ43830.1 - 0.057 13.0 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) O-antigen_lig PF13425.6 CDJ43830.1 - 0.059 12.1 0.0 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF1980 PF09323.10 CDJ43830.1 - 0.073 13.0 2.1 0.31 10.9 2.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) tRNA_anti-like PF12869.7 CDJ43830.1 - 0.082 12.5 0.0 0.082 12.5 0.0 2.5 2 1 0 2 2 1 0 tRNA_anti-like DUF2722 PF10846.8 CDJ43830.1 - 0.095 11.6 10.4 0.13 11.2 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) EMP70 PF02990.16 CDJ43830.1 - 0.099 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 DUF4228 PF14009.6 CDJ43830.1 - 0.11 12.9 1.5 4 7.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) FAM176 PF14851.6 CDJ43830.1 - 0.15 11.7 2.2 0.13 11.9 0.8 1.6 1 1 0 1 1 1 0 FAM176 family CPSF100_C PF13299.6 CDJ43830.1 - 0.15 12.2 3.7 1 9.5 0.1 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Dpy19 PF10034.9 CDJ43830.1 - 0.21 9.8 0.1 0.27 9.4 0.1 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF4114 PF13448.6 CDJ43830.1 - 0.26 12.1 0.2 0.43 11.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4114) GRP PF07172.11 CDJ43830.1 - 0.29 11.9 0.1 0.29 11.9 0.1 2.8 1 1 1 2 2 1 0 Glycine rich protein family Pex24p PF06398.11 CDJ43830.1 - 0.37 9.7 3.6 0.81 8.6 3.5 1.5 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Scs3p PF10261.9 CDJ43830.1 - 0.44 10.0 1.2 3.9 6.9 0.6 2.0 1 1 1 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM Orf78 PF06024.12 CDJ43830.1 - 0.58 10.5 5.5 4.9 7.5 0.1 2.7 2 1 0 2 2 2 0 Orf78 (ac78) WBP-1 PF11669.8 CDJ43830.1 - 1.1 9.9 10.1 0.45 11.2 5.1 2.3 1 1 1 2 2 2 0 WW domain-binding protein 1 Ribosomal_60s PF00428.19 CDJ43830.1 - 1.2 9.8 0.1 1.2 9.8 0.1 4.3 2 1 0 2 2 1 0 60s Acidic ribosomal protein Suf PF05843.14 CDJ43830.1 - 1.2 9.1 7.5 4.7 7.1 6.6 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PSK PF06404.12 CDJ43830.1 - 1.6 9.8 11.3 0.15 13.1 2.3 2.5 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) TFIIA PF03153.13 CDJ43830.1 - 3.4 7.6 19.1 0.31 11.0 12.2 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Mucin PF01456.17 CDJ43830.1 - 4 7.4 20.9 0.69 9.9 3.9 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein EIIBC-GUT_N PF03612.14 CDJ43830.1 - 4.2 7.1 4.9 4 7.1 2.4 1.9 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2101 PF09874.9 CDJ43830.1 - 6.4 6.4 4.9 9.1 5.9 4.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Lung_7-TM_R PF06814.13 CDJ43831.1 - 2.9e-24 85.8 1.7 3.8e-24 85.4 1.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 CDJ43831.1 - 0.00085 18.8 5.8 0.0014 18.1 5.8 1.4 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain FTZ PF03867.14 CDJ43831.1 - 0.15 11.5 3.4 0.22 11.0 3.4 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region AF-4 PF05110.13 CDJ43831.1 - 1.4 6.9 12.6 1.8 6.5 12.6 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AAA_assoc_C PF09821.9 CDJ43832.1 - 0.058 13.9 1.6 0.12 12.9 1.6 1.6 1 0 0 1 1 1 0 C-terminal AAA-associated domain Peptidase_S64 PF08192.11 CDJ43833.1 - 0.0024 16.4 11.4 0.0029 16.2 11.4 1.1 1 0 0 1 1 1 1 Peptidase family S64 Pex14_N PF04695.13 CDJ43833.1 - 0.0064 17.2 12.3 0.0064 17.2 12.3 3.4 2 1 1 3 3 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region NARP1 PF12569.8 CDJ43833.1 - 0.012 14.5 12.7 0.019 13.9 12.7 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Zip PF02535.22 CDJ43833.1 - 0.013 14.7 1.6 0.019 14.2 1.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Sin_N PF04801.13 CDJ43833.1 - 0.02 14.1 26.2 0.021 14.1 25.4 1.5 1 1 0 1 1 1 0 Sin-like protein conserved region FAM76 PF16046.5 CDJ43833.1 - 0.1 11.9 17.2 0.15 11.4 17.2 1.2 1 0 0 1 1 1 0 FAM76 protein OATP PF03137.20 CDJ43833.1 - 0.14 10.4 1.5 0.25 9.6 1.5 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Hid1 PF12722.7 CDJ43833.1 - 0.24 9.5 13.3 0.36 8.9 13.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Band_3_cyto PF07565.13 CDJ43833.1 - 0.34 10.7 18.0 0.028 14.2 12.4 1.8 1 1 1 2 2 2 0 Band 3 cytoplasmic domain Cellulose_synt PF03552.14 CDJ43833.1 - 0.49 8.8 4.0 0.62 8.5 4.0 1.1 1 0 0 1 1 1 0 Cellulose synthase Paramyxo_ncap PF00973.19 CDJ43833.1 - 0.61 9.0 9.2 0.94 8.3 9.2 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein HSP90 PF00183.18 CDJ43833.1 - 0.63 8.9 13.1 1.1 8.1 13.1 1.3 1 0 0 1 1 1 0 Hsp90 protein FAM176 PF14851.6 CDJ43833.1 - 0.89 9.2 15.5 0.5 10.0 12.5 1.9 2 0 0 2 2 2 0 FAM176 family TRAP_alpha PF03896.16 CDJ43833.1 - 1.3 8.2 10.4 0.29 10.3 7.1 1.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Afi1 PF07792.12 CDJ43833.1 - 1.5 9.3 16.8 2.1 8.8 14.3 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3527 PF12043.8 CDJ43833.1 - 1.7 8.2 13.2 0.46 10.0 10.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) Peroxin-13_N PF04088.13 CDJ43833.1 - 1.8 8.9 10.0 8.7 6.6 6.2 2.7 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF2052 PF09747.9 CDJ43833.1 - 2.1 8.4 26.7 0.098 12.8 18.5 2.1 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DDRGK PF09756.9 CDJ43833.1 - 2.3 7.8 29.5 0.16 11.6 24.4 1.6 2 0 0 2 2 2 0 DDRGK domain POPLD PF08170.12 CDJ43833.1 - 2.8 8.4 11.2 19 5.7 8.1 2.6 2 0 0 2 2 2 0 POPLD (NUC188) domain DUF2370 PF10176.9 CDJ43833.1 - 2.8 7.5 8.1 1 8.9 4.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) PPL5 PF18168.1 CDJ43833.1 - 5.3 6.2 18.6 2.2 7.5 16.0 1.6 1 1 1 2 2 2 0 Prim-pol family 5 Bul1_N PF04425.12 CDJ43833.1 - 6.1 5.5 12.0 0.75 8.5 8.2 1.4 2 0 0 2 2 2 0 Bul1 N terminus EFTUD2 PF16004.5 CDJ43833.1 - 8.6 7.0 23.4 14 6.2 19.1 2.3 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus RPN2_C PF18004.1 CDJ43833.1 - 9.9 6.1 22.9 3.4 7.6 19.2 2.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain INO80_Ies4 PF08193.11 CDJ43834.1 - 0.51 10.3 6.0 0.6 10.1 6.0 1.1 1 0 0 1 1 1 0 INO80 complex subunit Ies4 Peptidase_S8 PF00082.22 CDJ43835.1 - 0.00049 19.5 1.2 0.00049 19.5 1.2 1.9 2 0 0 2 2 2 1 Subtilase family Sin_N PF04801.13 CDJ43835.1 - 0.08 12.1 38.6 0.031 13.5 35.3 1.8 2 0 0 2 2 2 0 Sin-like protein conserved region Ribosomal_60s PF00428.19 CDJ43835.1 - 0.1 13.2 0.3 0.1 13.2 0.3 4.0 3 1 0 3 3 3 0 60s Acidic ribosomal protein Peptidase_S8_N PF16361.5 CDJ43835.1 - 0.48 10.9 0.0 0.48 10.9 0.0 3.4 3 1 0 3 3 3 0 N-terminal of Subtilase family DUF778 PF05608.12 CDJ43835.1 - 4.3 7.7 7.3 6.3 7.1 5.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF778) MDM10 PF12519.8 CDJ43835.1 - 5.1 5.8 14.0 2.3 7.0 9.2 2.2 3 0 0 3 3 3 0 Mitochondrial distribution and morphology protein 10 DUF4179 PF13786.6 CDJ43835.1 - 7.7 7.1 7.6 14 6.2 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) SPOC PF07744.13 CDJ43838.1 - 0.0048 16.8 0.0 0.0084 16.0 0.0 1.3 1 0 0 1 1 1 1 SPOC domain SR-25 PF10500.9 CDJ43838.1 - 6.2 6.4 29.7 13 5.3 29.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.11 CDJ43839.1 - 0.0019 16.4 0.0 0.0033 15.6 0.0 1.4 1 1 0 1 1 1 1 Sporozoite P67 surface antigen TFIIA PF03153.13 CDJ43839.1 - 0.0071 16.4 6.3 0.0089 16.1 6.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PGA_cap PF09587.10 CDJ43839.1 - 0.014 14.8 1.2 0.026 14.0 1.2 1.3 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap DAG_kinase_N PF14513.6 CDJ43839.1 - 0.081 13.1 2.3 0.13 12.5 2.3 1.5 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus SUIM_assoc PF16619.5 CDJ43839.1 - 6.5 6.9 14.5 22 5.2 0.1 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2967 PF11179.8 CDJ43840.1 - 0.024 12.8 2.2 0.027 12.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF4175 PF13779.6 CDJ43842.1 - 0.0043 15.0 34.3 0.0049 14.9 34.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) TFIIA PF03153.13 CDJ43842.1 - 0.0063 16.6 54.1 0.0081 16.2 54.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 CDJ43842.1 - 0.056 12.8 15.3 0.063 12.6 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAT1 PF09770.9 CDJ43842.1 - 0.074 11.3 33.4 0.084 11.1 33.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 O-antigen_lig PF13425.6 CDJ43842.1 - 0.74 8.5 3.5 1 8.0 3.5 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein NARP1 PF12569.8 CDJ43842.1 - 0.8 8.5 16.8 1.2 8.0 16.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Utp14 PF04615.13 CDJ43842.1 - 0.82 8.2 42.6 1 7.8 42.6 1.0 1 0 0 1 1 1 0 Utp14 protein DDRGK PF09756.9 CDJ43842.1 - 1.2 8.6 24.2 1.7 8.2 24.2 1.1 1 0 0 1 1 1 0 DDRGK domain Kei1 PF08552.11 CDJ43844.1 - 0.00074 19.4 3.0 0.00074 19.4 3.0 2.7 2 1 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 MDFI PF15316.6 CDJ43844.1 - 0.0039 17.3 13.2 0.0039 17.3 13.2 3.1 2 1 1 3 3 3 1 MyoD family inhibitor Afi1 PF07792.12 CDJ43844.1 - 0.32 11.5 10.9 0.82 10.2 10.9 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking eIF-3_zeta PF05091.12 CDJ43844.1 - 0.98 8.3 18.3 1.4 7.8 18.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2126 PF09899.9 CDJ43844.1 - 2.9 5.8 7.3 3.9 5.4 7.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Scs3p PF10261.9 CDJ43844.1 - 3.9 6.9 8.2 0.34 10.4 2.2 2.2 2 1 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM ALMT PF11744.8 CDJ43844.1 - 9.3 5.0 18.3 0.011 14.6 4.9 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF4746 PF15928.5 CDJ43844.1 - 9.6 5.5 10.0 13 5.1 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CPSF100_C PF13299.6 CDJ43844.1 - 9.9 6.3 12.5 23 5.1 12.5 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Ribosomal_S9 PF00380.19 CDJ43845.1 - 7.7e-14 52.3 0.2 9.6e-13 48.7 0.0 2.7 2 1 0 2 2 2 1 Ribosomal protein S9/S16 tRNA_int_endo_N PF02778.14 CDJ43845.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Med15 PF09606.10 CDJ43846.1 - 0.00066 18.5 4.8 0.00084 18.2 4.8 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Connexin PF00029.19 CDJ43846.1 - 0.065 13.0 2.8 0.087 12.6 2.8 1.3 1 1 0 1 1 1 0 Connexin Ribosomal_60s PF00428.19 CDJ43846.1 - 0.27 11.8 12.0 1.5 9.4 1.7 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein ERF PF04404.12 CDJ43846.1 - 0.73 9.7 7.7 0.08 12.8 2.4 1.9 2 0 0 2 2 2 0 ERF superfamily TFIIA PF03153.13 CDJ43846.1 - 4.3 7.2 17.7 6 6.8 17.7 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sin_N PF04801.13 CDJ43847.1 - 1.2e-06 28.0 0.1 1.7e-06 27.5 0.1 1.2 1 1 0 1 1 1 1 Sin-like protein conserved region Bac_transf PF02397.16 CDJ43848.1 - 0.22 11.1 0.5 0.44 10.1 0.5 1.4 1 0 0 1 1 1 0 Bacterial sugar transferase Presenilin PF01080.17 CDJ43848.1 - 0.75 8.5 12.9 0.11 11.2 1.6 2.2 2 0 0 2 2 2 0 Presenilin SUIM_assoc PF16619.5 CDJ43849.1 - 0.0061 16.6 3.0 0.0061 16.6 3.0 4.7 5 0 0 5 5 5 2 Unstructured region C-term to UIM in Ataxin3 CRCB PF02537.15 CDJ43852.1 - 0.011 16.0 2.3 0.024 14.9 2.3 1.5 1 0 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) IBV_3C PF03620.13 CDJ43852.1 - 0.66 10.5 2.7 0.58 10.7 0.7 1.9 2 0 0 2 2 2 0 IBV 3C protein Hydrolase PF00702.26 CDJ43853.1 - 5.6e-10 39.9 4.2 0.00023 21.5 0.8 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase TFIIA PF03153.13 CDJ43853.1 - 0.51 10.3 27.5 0.092 12.7 1.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Bac_GDH PF05088.12 CDJ43855.1 - 8 3.8 18.3 9.1 3.6 18.3 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase SUIM_assoc PF16619.5 CDJ43856.1 - 0.17 11.9 3.8 0.39 10.8 3.8 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ashwin PF15323.6 CDJ43856.1 - 0.88 9.5 6.4 0.62 10.1 2.8 1.9 2 0 0 2 2 2 0 Developmental protein TPR_9 PF13371.6 CDJ43857.1 - 0.00017 21.7 0.9 0.00046 20.3 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat SR-25 PF10500.9 CDJ43857.1 - 0.0062 16.2 1.8 0.0062 16.2 1.8 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Fmp27 PF10344.9 CDJ43857.1 - 0.11 10.6 0.1 0.18 9.9 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 TPR_6 PF13174.6 CDJ43857.1 - 0.23 12.2 1.5 15 6.5 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 CDJ43859.1 - 5.6e-05 22.8 1.6 0.0011 18.5 1.6 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RINT1_TIP1 PF04437.13 CDJ43860.1 - 5.1e-05 22.3 0.0 0.00067 18.7 0.0 2.0 1 1 0 1 1 1 1 RINT-1 / TIP-1 family Sec6 PF06046.13 CDJ43860.1 - 0.033 12.6 0.0 0.13 10.6 0.0 1.7 1 1 0 1 1 1 0 Exocyst complex component Sec6 VPS53_C PF16854.5 CDJ43860.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus JUPITER PF17054.5 CDJ43860.1 - 0.36 10.3 2.9 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter DUF4620 PF15399.6 CDJ43860.1 - 5.2 7.4 7.2 5.1 7.5 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4620) Apt1 PF10351.9 CDJ43861.1 - 0.34 9.7 2.4 0.33 9.7 2.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.13 CDJ43861.1 - 1.3 7.3 3.9 1.3 7.2 3.9 1.0 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 CDJ43861.1 - 6.2 5.5 5.9 6.9 5.3 5.9 1.1 1 0 0 1 1 1 0 Presenilin SUIM_assoc PF16619.5 CDJ43865.1 - 7.7e-05 22.7 0.0 7.7e-05 22.7 0.0 5.8 4 2 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 CDC24_OB1 PF17246.2 CDJ43865.1 - 0.023 14.8 0.7 0.023 14.8 0.7 2.1 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 1 MecA PF05389.12 CDJ43865.1 - 0.038 13.6 1.8 1 9.0 0.2 2.5 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) FHIPEP PF00771.20 CDJ43865.1 - 0.18 10.2 2.0 1.8 7.0 0.6 2.3 2 0 0 2 2 2 0 FHIPEP family eIF-3_zeta PF05091.12 CDJ43865.1 - 0.26 10.2 8.9 0.36 9.8 0.4 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_lid_7 PF17867.1 CDJ43865.1 - 2.2 8.5 5.9 2.4 8.4 4.0 2.1 1 1 0 1 1 1 0 Midasin AAA lid domain Sporozoite_P67 PF05642.11 CDJ43865.1 - 2.9 5.9 21.8 0.2 9.7 7.0 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Rpp20 PF12328.8 CDJ43865.1 - 5.1 7.0 9.0 1.4 8.9 0.6 2.5 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Peptidase_S49_N PF08496.10 CDJ43865.1 - 7.6 6.6 8.7 7.3 6.6 3.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal TMEM247 PF15444.6 CDJ43866.1 - 0.19 11.7 5.4 0.19 11.8 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 DUF2098 PF09871.9 CDJ43866.1 - 0.92 9.9 4.5 1 9.7 4.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) DUF2370 PF10176.9 CDJ43867.1 - 0.0007 19.3 1.5 0.00087 19.0 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) CCSAP PF15748.5 CDJ43867.1 - 0.0061 16.8 17.8 0.0063 16.7 17.8 1.0 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated DUF4746 PF15928.5 CDJ43867.1 - 0.01 15.3 2.4 0.012 15.1 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PepSY_TM PF03929.16 CDJ43867.1 - 0.037 13.7 1.1 0.053 13.2 1.1 1.3 1 0 0 1 1 1 0 PepSY-associated TM region V_ATPase_I PF01496.19 CDJ43867.1 - 0.1 10.5 13.5 0.11 10.4 13.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lin-8 PF03353.15 CDJ43867.1 - 0.14 11.7 16.0 0.17 11.5 16.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FAM60A PF15396.6 CDJ43867.1 - 0.15 12.0 11.2 0.2 11.7 11.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF2235 PF09994.9 CDJ43867.1 - 0.22 10.8 9.3 0.52 9.6 9.3 1.6 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) SLC12 PF03522.15 CDJ43867.1 - 0.23 10.4 15.2 0.26 10.2 15.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 LAP1C PF05609.12 CDJ43867.1 - 0.35 9.9 17.9 0.38 9.8 17.9 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 CDJ43867.1 - 0.35 9.6 21.7 0.42 9.3 21.7 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CDJ43867.1 - 0.51 9.5 12.4 0.63 9.2 12.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 CDJ43867.1 - 0.8 8.4 13.5 0.95 8.2 13.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GREB1 PF15782.5 CDJ43867.1 - 0.85 6.7 17.0 0.86 6.6 17.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Gti1_Pac2 PF09729.9 CDJ43867.1 - 1.3 9.1 13.1 1.9 8.6 13.1 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family VIT1 PF01988.19 CDJ43867.1 - 1.5 8.7 4.2 2.1 8.2 4.2 1.3 1 0 0 1 1 1 0 VIT family HCO3_cotransp PF00955.21 CDJ43867.1 - 1.5 7.6 3.8 1.6 7.5 3.8 1.1 1 0 0 1 1 1 0 HCO3- transporter family Peptidase_S49_N PF08496.10 CDJ43867.1 - 1.5 8.9 12.5 2.2 8.3 12.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TFIIA PF03153.13 CDJ43867.1 - 1.6 8.6 42.8 2.3 8.1 42.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ43867.1 - 2.2 7.8 17.0 2.3 7.7 17.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit cwf18 PF08315.12 CDJ43867.1 - 2.2 8.9 15.5 2.8 8.6 15.5 1.1 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor MDM10 PF12519.8 CDJ43867.1 - 2.2 7.0 10.9 2.4 6.9 10.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Ribosomal_S17 PF00366.20 CDJ43867.1 - 2.6 8.2 4.4 5 7.3 4.4 1.4 1 0 0 1 1 1 0 Ribosomal protein S17 Nucleoside_tran PF01733.18 CDJ43867.1 - 2.6 7.3 3.4 3.2 7.0 3.4 1.2 1 0 0 1 1 1 0 Nucleoside transporter RR_TM4-6 PF06459.12 CDJ43867.1 - 3.6 7.3 18.2 4.2 7.1 18.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ43867.1 - 4 7.4 13.4 5.2 7.0 13.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 CDJ43867.1 - 4.3 5.5 14.8 4.9 5.3 14.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Otopetrin PF03189.13 CDJ43867.1 - 5 5.8 7.7 6.3 5.5 7.7 1.3 1 0 0 1 1 1 0 Otopetrin DUF2828 PF11443.8 CDJ43867.1 - 5.7 4.9 15.5 6.9 4.6 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4407 PF14362.6 CDJ43867.1 - 5.9 6.1 16.1 7.8 5.7 16.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SelP_N PF04592.14 CDJ43867.1 - 8 5.8 29.8 10 5.4 29.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PAT1 PF09770.9 CDJ43867.1 - 9 4.4 33.4 11 4.2 33.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM217 PF15344.6 CDJ43867.1 - 9.2 6.1 24.1 11 5.9 24.1 1.1 1 0 0 1 1 1 0 FAM217 family Spt20 PF12090.8 CDJ43869.1 - 0.00042 20.0 18.0 0.00051 19.7 18.0 1.2 1 0 0 1 1 1 1 Spt20 family Androgen_recep PF02166.16 CDJ43869.1 - 0.00046 19.2 10.8 0.00054 18.9 10.8 1.2 1 0 0 1 1 1 1 Androgen receptor SR-25 PF10500.9 CDJ43869.1 - 0.0017 18.0 10.0 0.002 17.8 10.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ43869.1 - 0.0045 16.0 18.4 0.0053 15.8 18.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ43869.1 - 0.017 15.1 16.1 0.019 15.0 16.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.6 CDJ43869.1 - 0.026 12.4 8.2 0.026 12.5 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BT1 PF03092.16 CDJ43869.1 - 0.047 11.9 0.8 0.055 11.7 0.8 1.0 1 0 0 1 1 1 0 BT1 family DUF913 PF06025.12 CDJ43869.1 - 0.062 12.3 3.0 0.068 12.1 3.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CNDH2_N PF06278.11 CDJ43869.1 - 0.065 13.5 4.3 0.12 12.6 4.3 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal BRF1 PF07741.13 CDJ43869.1 - 0.075 13.4 3.4 0.1 13.0 3.4 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain CPSF100_C PF13299.6 CDJ43869.1 - 0.078 13.2 3.1 0.096 12.9 3.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Activator_LAG-3 PF11498.8 CDJ43869.1 - 0.096 11.6 17.7 0.11 11.4 17.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 MPM1 PF17234.2 CDJ43869.1 - 0.14 12.4 9.0 0.19 12.0 9.0 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 TERB2 PF15101.6 CDJ43869.1 - 0.19 11.7 9.0 0.24 11.5 9.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4407 PF14362.6 CDJ43869.1 - 0.21 10.9 3.1 0.26 10.6 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Roughex PF06020.11 CDJ43869.1 - 0.47 9.5 9.4 0.53 9.3 9.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Membralin PF09746.9 CDJ43869.1 - 1.1 8.2 3.4 1.3 8.0 3.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein CLN3 PF02487.17 CDJ43869.1 - 1.2 8.1 3.7 1.4 7.9 3.7 1.0 1 0 0 1 1 1 0 CLN3 protein DivIC PF04977.15 CDJ43869.1 - 1.3 8.8 10.7 2 8.2 10.7 1.3 1 0 0 1 1 1 0 Septum formation initiator Lin-8 PF03353.15 CDJ43869.1 - 1.5 8.3 10.2 1.7 8.2 10.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CobT PF06213.12 CDJ43869.1 - 2.1 7.6 10.6 2.7 7.3 10.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 CDJ43869.1 - 2.4 6.8 10.4 2.7 6.7 10.4 1.0 1 0 0 1 1 1 0 Presenilin Kei1 PF08552.11 CDJ43869.1 - 3.4 7.5 6.3 4.3 7.2 6.3 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 ALMT PF11744.8 CDJ43869.1 - 4.5 6.0 7.5 5.3 5.8 7.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DEAD PF00270.29 CDJ43870.1 - 1.3e-06 28.3 0.0 1.3e-06 28.3 0.0 2.0 2 1 0 2 2 1 1 DEAD/DEAH box helicase CCSAP PF15748.5 CDJ43870.1 - 0.0025 18.1 28.2 0.0031 17.7 28.2 1.1 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated PAT1 PF09770.9 CDJ43870.1 - 0.0032 15.8 23.9 0.0035 15.7 23.9 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DDRGK PF09756.9 CDJ43870.1 - 0.017 14.7 24.8 0.03 13.9 24.8 1.4 1 0 0 1 1 1 0 DDRGK domain Otopetrin PF03189.13 CDJ43870.1 - 0.31 9.8 1.4 0.33 9.7 1.4 1.2 1 0 0 1 1 1 0 Otopetrin SOBP PF15279.6 CDJ43870.1 - 0.43 11.1 14.0 0.5 10.9 14.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Lin-8 PF03353.15 CDJ43870.1 - 0.46 10.0 16.6 0.53 9.8 16.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 CDJ43870.1 - 0.55 8.9 23.2 0.7 8.6 23.2 1.2 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 CDJ43870.1 - 0.68 8.3 18.8 0.87 8.0 18.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SLC12 PF03522.15 CDJ43870.1 - 0.71 8.8 16.1 0.83 8.6 16.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF5427 PF10310.9 CDJ43870.1 - 0.76 8.7 25.9 1.1 8.2 25.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF4746 PF15928.5 CDJ43870.1 - 0.77 9.1 12.4 1.1 8.6 12.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Ndc1_Nup PF09531.10 CDJ43870.1 - 0.9 8.2 15.3 1.1 7.8 15.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 CDJ43870.1 - 1 8.1 11.4 1.1 8.0 11.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BORG_CEP PF14957.6 CDJ43870.1 - 1.1 10.4 10.9 1.6 9.9 10.9 1.4 1 0 0 1 1 1 0 Cdc42 effector FAM60A PF15396.6 CDJ43870.1 - 1.2 9.1 16.2 1.5 8.7 16.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PA26 PF04636.13 CDJ43870.1 - 1.4 7.8 11.1 1.8 7.4 11.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CDC45 PF02724.14 CDJ43870.1 - 1.7 6.8 19.0 2.1 6.6 19.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Plasmodium_Vir PF05795.11 CDJ43870.1 - 2.1 7.7 11.0 2.5 7.4 11.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ALMT PF11744.8 CDJ43870.1 - 2.1 7.1 10.9 2.4 6.9 10.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF913 PF06025.12 CDJ43870.1 - 2.4 7.1 11.8 3.5 6.5 11.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 CDJ43870.1 - 2.5 6.8 18.9 3 6.5 18.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Band_3_cyto PF07565.13 CDJ43870.1 - 2.5 7.8 12.9 3.7 7.3 12.9 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.16 CDJ43870.1 - 3 7.8 13.2 4 7.4 13.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Endostatin PF06482.11 CDJ43870.1 - 3 7.2 14.7 3.8 6.9 14.7 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Zip PF02535.22 CDJ43870.1 - 3.5 6.7 10.3 4.7 6.3 10.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Raftlin PF15250.6 CDJ43870.1 - 5 5.7 16.9 6.2 5.5 16.9 1.1 1 0 0 1 1 1 0 Raftlin DUF4551 PF15087.6 CDJ43870.1 - 7.2 5.3 15.3 8.3 5.1 15.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Peptidase_S30 PF01577.16 CDJ43870.1 - 8 6.0 18.6 12 5.4 18.6 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease Membralin PF09746.9 CDJ43870.1 - 8.2 5.4 6.8 9.6 5.1 6.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein Hamartin PF04388.12 CDJ43870.1 - 8.6 4.9 17.3 11 4.6 17.3 1.0 1 0 0 1 1 1 0 Hamartin protein DUF2828 PF11443.8 CDJ43870.1 - 8.9 4.3 15.9 13 3.7 15.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) IHABP4_N PF16174.5 CDJ43870.1 - 9.7 6.8 35.6 15 6.1 35.6 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal RR_TM4-6 PF06459.12 CDJ43870.1 - 9.9 5.9 24.6 18 5.1 24.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PDEase_I PF00233.19 CDJ43871.1 - 9.1e-24 84.5 0.7 3.3e-17 63.0 0.4 2.0 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CDJ43871.1 - 0.0035 17.6 0.0 0.0046 17.2 0.0 1.2 1 0 0 1 1 1 1 HD domain SUIM_assoc PF16619.5 CDJ43872.1 - 0.3 11.2 5.8 0.32 11.1 5.8 1.1 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 BatD PF13584.6 CDJ43873.1 - 0.33 9.7 0.2 0.54 9.0 0.2 1.3 1 0 0 1 1 1 0 Oxygen tolerance DUF4131 PF13567.6 CDJ43873.1 - 3.5 7.2 15.6 2.2 7.9 7.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) EXOSC1 PF10447.9 CDJ43874.1 - 9e-06 26.3 0.0 1.3e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 Ribonuc_red_sm PF00268.21 CDJ43875.1 - 2.2e-73 247.1 3.8 3e-73 246.7 3.8 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Haem_oxygenas_2 PF14518.6 CDJ43875.1 - 0.00069 19.4 0.5 0.00087 19.1 0.5 1.3 1 0 0 1 1 1 1 Iron-containing redox enzyme Macoilin PF09726.9 CDJ43876.1 - 0.0091 14.6 8.7 0.012 14.3 8.7 1.2 1 0 0 1 1 1 1 Macoilin family SPX PF03105.19 CDJ43876.1 - 0.051 13.5 4.7 0.063 13.2 4.7 1.3 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ43876.1 - 0.055 12.3 5.6 0.061 12.2 5.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1180 PF06679.12 CDJ43876.1 - 0.062 13.7 5.3 0.11 13.0 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4614 PF15391.6 CDJ43876.1 - 3.2 7.7 17.0 5.9 6.8 17.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) PgaD PF13994.6 CDJ43877.1 - 0.18 11.9 0.3 0.46 10.5 0.3 1.7 1 0 0 1 1 1 0 PgaD-like protein Med15 PF09606.10 CDJ43877.1 - 0.23 10.1 46.6 0.3 9.7 46.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.8 CDJ43877.1 - 0.74 8.7 54.6 1.1 8.1 4.0 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 RskA PF10099.9 CDJ43882.1 - 0.047 14.0 12.9 0.064 13.5 12.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ43882.1 - 0.59 10.1 22.5 0.67 9.9 22.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 CDJ43882.1 - 4.2 7.4 8.7 6.7 6.7 8.7 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Myb_DNA-bind_3 PF12776.7 CDJ43884.1 - 1.3 10.1 6.5 3.9 8.5 6.5 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain FXR_C1 PF16096.5 CDJ43885.1 - 0.033 14.4 2.2 0.059 13.6 2.2 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 cEGF PF12662.7 CDJ43889.1 - 7.7e-12 44.9 13.2 1.4e-07 31.3 0.2 3.5 3 0 0 3 3 3 3 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CDJ43889.1 - 6.8e-10 39.1 26.9 1.1e-06 28.9 3.4 3.6 3 1 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CDJ43889.1 - 4.7e-08 33.1 11.0 2.3e-06 27.7 1.5 4.0 4 0 0 4 4 4 2 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ43889.1 - 6.3e-05 23.1 17.2 0.0084 16.3 0.3 4.5 2 2 0 3 3 3 2 EGF domain EGF PF00008.27 CDJ43889.1 - 3.1 8.2 29.5 0.37 11.1 3.7 4.2 3 1 0 3 3 3 0 EGF-like domain XRN_M PF17846.1 CDJ43890.1 - 3.2e-49 168.1 0.0 1.3e-28 100.2 0.1 2.2 2 0 0 2 2 2 2 Xrn1 helical domain Methyltransf_28 PF02636.17 CDJ43890.1 - 0.004 16.8 0.2 0.0061 16.2 0.2 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TFIIA PF03153.13 CDJ43890.1 - 0.041 13.9 18.9 0.05 13.6 18.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ43890.1 - 0.048 13.3 13.7 0.066 12.8 13.7 1.2 1 0 0 1 1 1 0 Spt20 family SprA-related PF12118.8 CDJ43891.1 - 0.0047 16.1 25.5 0.0061 15.7 25.5 1.1 1 0 0 1 1 1 1 SprA-related family TCP PF03634.13 CDJ43891.1 - 0.035 14.7 19.6 0.044 14.4 19.6 1.2 1 0 0 1 1 1 0 TCP family transcription factor SID-1_RNA_chan PF13965.6 CDJ43891.1 - 0.068 11.6 2.6 0.073 11.5 2.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PA26 PF04636.13 CDJ43891.1 - 0.12 11.3 5.8 0.14 11.1 5.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF1501 PF07394.12 CDJ43891.1 - 0.13 11.3 11.3 0.15 11.1 11.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) RR_TM4-6 PF06459.12 CDJ43891.1 - 0.2 11.5 18.1 0.22 11.3 18.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hamartin PF04388.12 CDJ43891.1 - 0.24 10.0 13.3 0.28 9.8 13.3 1.0 1 0 0 1 1 1 0 Hamartin protein CCSAP PF15748.5 CDJ43891.1 - 0.28 11.3 28.2 0.32 11.1 28.2 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 CDJ43891.1 - 0.38 9.5 20.7 0.52 9.0 20.7 1.3 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 CDJ43891.1 - 0.46 10.7 12.6 0.62 10.2 12.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 CDJ43891.1 - 0.5 10.5 14.3 0.66 10.1 14.3 1.2 1 0 0 1 1 1 0 DDHD domain SLC12 PF03522.15 CDJ43891.1 - 0.8 8.7 16.3 0.9 8.5 16.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SR-25 PF10500.9 CDJ43891.1 - 0.98 9.0 42.4 1.8 8.1 39.5 2.0 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein SpoIIP PF07454.11 CDJ43891.1 - 1.1 8.6 17.9 1.4 8.3 17.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PPP4R2 PF09184.11 CDJ43891.1 - 1.2 8.6 15.8 1.6 8.2 15.8 1.2 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 CDJ43891.1 - 1.3 7.7 12.4 1.4 7.7 12.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 CDJ43891.1 - 2.2 7.2 10.9 2.5 7.0 10.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tim54 PF11711.8 CDJ43891.1 - 2.4 6.8 17.2 3.2 6.4 17.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF-3_zeta PF05091.12 CDJ43891.1 - 5.2 5.9 23.6 5.5 5.8 23.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) U79_P34 PF03064.16 CDJ43891.1 - 5.6 6.2 22.8 7.7 5.8 22.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 HemX PF04375.14 CDJ43891.1 - 8.3 5.6 27.4 10 5.3 27.4 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase SUIM_assoc PF16619.5 CDJ43892.1 - 0.063 13.4 0.4 0.063 13.4 0.4 8.4 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ43893.1 - 0.03 14.0 14.5 0.41 10.2 5.5 2.2 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ43893.1 - 0.23 10.4 10.1 0.54 9.1 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ43893.1 - 0.99 9.5 25.3 3.3 7.8 10.0 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 UPF0560 PF10577.9 CDJ43893.1 - 2.4 6.6 11.6 0.29 9.6 1.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 RNA_pol_L PF01193.24 CDJ43895.1 - 4.9e-08 32.3 0.0 5.4e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.7 CDJ43895.1 - 0.018 15.6 0.3 0.038 14.6 0.3 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain ETF_QO PF05187.13 CDJ43895.1 - 0.025 14.7 0.1 0.041 14.0 0.1 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S TFIIA PF03153.13 CDJ43896.1 - 0.028 14.4 19.9 0.03 14.3 19.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dynein_attach_N PF15867.5 CDJ43897.1 - 1.6 8.7 4.8 1.2 9.2 1.9 2.0 1 1 1 2 2 2 0 Dynein attachment factor N-terminus HA2 PF04408.23 CDJ43898.1 - 8.2e-20 71.1 1.3 5.5e-19 68.4 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ43898.1 - 2.9e-17 62.8 0.0 1.1e-16 61.0 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ43898.1 - 8.5e-09 35.7 0.0 1.8e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Spt20 PF12090.8 CDJ43898.1 - 0.75 9.4 7.4 1.2 8.7 7.4 1.2 1 0 0 1 1 1 0 Spt20 family Cwf_Cwc_15 PF04889.12 CDJ43899.1 - 0.0019 18.0 0.3 0.0026 17.5 0.3 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Secretin_N_2 PF07655.13 CDJ43899.1 - 0.0067 17.0 11.8 0.0094 16.5 11.8 1.2 1 0 0 1 1 1 1 Secretin N-terminal domain NPR3 PF03666.13 CDJ43899.1 - 0.013 14.4 5.4 0.017 14.0 5.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Miga PF10265.9 CDJ43899.1 - 0.016 14.2 6.0 0.015 14.3 6.0 1.1 1 0 0 1 1 1 0 Mitoguardin RNF220 PF15926.5 CDJ43899.1 - 0.036 13.7 6.1 0.054 13.1 6.1 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 Apt1 PF10351.9 CDJ43899.1 - 0.039 12.8 7.0 0.043 12.7 7.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ43899.1 - 0.042 13.8 9.1 0.053 13.4 9.1 1.2 1 0 0 1 1 1 0 SPX domain IATP PF04568.12 CDJ43899.1 - 0.049 14.1 1.1 0.049 14.1 1.1 2.4 2 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Peptidase_S64 PF08192.11 CDJ43899.1 - 0.092 11.2 6.5 0.097 11.1 6.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 SR-25 PF10500.9 CDJ43899.1 - 0.11 12.1 32.8 0.29 10.7 32.6 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Suf PF05843.14 CDJ43899.1 - 0.15 12.0 4.8 0.18 11.8 4.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4614 PF15391.6 CDJ43899.1 - 0.17 11.8 17.0 0.34 10.9 17.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CSG2 PF16965.5 CDJ43899.1 - 0.18 10.7 1.6 0.21 10.5 1.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Corona_nucleoca PF00937.18 CDJ43899.1 - 0.25 10.3 8.0 0.3 10.1 8.0 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein TFIIA PF03153.13 CDJ43899.1 - 0.31 11.0 11.7 0.42 10.5 11.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gti1_Pac2 PF09729.9 CDJ43899.1 - 0.33 11.0 8.0 0.52 10.4 8.0 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family PI3K_1B_p101 PF10486.9 CDJ43899.1 - 0.34 8.7 10.8 0.43 8.3 10.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 CDJ43899.1 - 0.43 9.3 4.9 0.44 9.3 4.9 1.2 1 0 0 1 1 1 0 Presenilin DUF3617 PF12276.8 CDJ43899.1 - 0.43 10.9 8.3 0.8 10.0 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) DUF1635 PF07795.11 CDJ43899.1 - 1.2 9.0 11.2 1.8 8.3 11.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) RAP1 PF07218.11 CDJ43899.1 - 1.7 6.9 11.0 1.7 6.8 11.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CCDC106 PF15794.5 CDJ43899.1 - 6.3 6.4 14.1 11 5.7 14.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 NAM-associated PF14303.6 CDJ43899.1 - 7.4 7.3 14.1 0.38 11.5 7.8 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Plasmodium_Vir PF05795.11 CDJ43900.1 - 0.032 13.7 8.5 0.05 13.0 8.5 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TctA PF01970.16 CDJ43900.1 - 2.2 6.9 3.5 3.2 6.4 3.5 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family hDGE_amylase PF14701.6 CDJ43900.1 - 2.3 7.2 6.7 3.9 6.5 6.7 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain XRN_M PF17846.1 CDJ43900.1 - 6.8 5.5 7.9 10 5.0 7.9 1.4 1 0 0 1 1 1 0 Xrn1 helical domain Ndc1_Nup PF09531.10 CDJ43901.1 - 2.5 6.7 8.6 2.8 6.5 8.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Retinal PF15449.6 CDJ43901.1 - 2.6 5.7 17.1 2.8 5.6 17.1 1.0 1 0 0 1 1 1 0 Retinal protein Pol_alpha_B_N PF08418.10 CDJ43901.1 - 7.8 6.4 9.4 9.8 6.1 9.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Spt20 PF12090.8 CDJ43902.1 - 0.14 11.8 8.7 0.15 11.6 8.7 1.1 1 0 0 1 1 1 0 Spt20 family Caldesmon PF02029.15 CDJ43903.1 - 0.1 11.4 44.1 0.14 10.9 44.1 1.1 1 0 0 1 1 1 0 Caldesmon CDC45 PF02724.14 CDJ43903.1 - 0.78 8.0 39.6 0.058 11.7 32.7 1.9 2 0 0 2 2 2 0 CDC45-like protein SAPS PF04499.15 CDJ43903.1 - 1 8.0 26.8 1.4 7.6 26.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4045 PF13254.6 CDJ43903.1 - 2.9 7.4 40.3 4.1 6.9 40.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Nop53 PF07767.11 CDJ43903.1 - 3.7 6.8 47.9 4.3 6.6 38.7 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) GREB1 PF15782.5 CDJ43903.1 - 6.9 3.7 33.3 8.4 3.4 33.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 CDJ43903.1 - 9.7 4.7 34.9 12 4.4 34.9 1.1 1 0 0 1 1 1 0 Hamartin protein Peptidase_C12 PF01088.21 CDJ43904.1 - 5.4e-09 36.1 0.5 6.2e-08 32.6 0.2 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 TraT PF05818.12 CDJ43905.1 - 5.4 6.6 5.4 1.1 9.0 0.7 2.0 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein ThiF PF00899.21 CDJ43906.1 - 4.9e-06 26.1 0.0 6.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family DNA_pol_A PF00476.20 CDJ43909.1 - 1.9e-54 185.1 0.0 2.6e-47 161.7 0.0 2.0 2 0 0 2 2 2 2 DNA polymerase family A LRRNT PF01462.18 CDJ43909.1 - 0.028 14.1 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Androgen_recep PF02166.16 CDJ43909.1 - 1.9 7.3 21.4 7.3 5.3 20.9 1.9 2 0 0 2 2 2 0 Androgen receptor PepSY_TM PF03929.16 CDJ43910.1 - 0.058 13.1 1.0 0.072 12.7 1.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region TFIIA PF03153.13 CDJ43910.1 - 8.3 6.3 20.5 12 5.8 20.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ43910.1 - 8.5 4.5 14.6 10 4.3 14.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mtc PF03820.17 CDJ43911.1 - 0.5 9.4 3.9 0.86 8.6 3.9 1.3 1 0 0 1 1 1 0 Tricarboxylate carrier WBP-1 PF11669.8 CDJ43912.1 - 0.24 12.1 2.9 0.46 11.1 2.5 1.5 1 1 1 2 2 2 0 WW domain-binding protein 1 Red1 PF07964.11 CDJ43912.1 - 0.44 8.7 1.8 0.5 8.5 1.8 1.0 1 0 0 1 1 1 0 Rec10 / Red1 T2SSF PF00482.23 CDJ43913.1 - 0.0031 17.5 1.2 0.0053 16.7 1.2 1.4 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F LpxB PF02684.15 CDJ43913.1 - 0.15 10.8 2.2 0.19 10.5 2.2 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase BRF1 PF07741.13 CDJ43913.1 - 0.36 11.2 3.2 0.53 10.6 3.2 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Spt20 PF12090.8 CDJ43913.1 - 0.44 10.1 11.8 0.6 9.7 11.8 1.3 1 0 0 1 1 1 0 Spt20 family DUF4179 PF13786.6 CDJ43913.1 - 3.3 8.2 7.4 44 4.6 6.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) PsbW PF07123.12 CDJ43913.1 - 4.3 7.3 10.5 1.3 9.0 7.1 1.8 1 1 1 2 2 2 0 Photosystem II reaction centre W protein (PsbW) RskA PF10099.9 CDJ43913.1 - 7.5 6.8 25.4 1 9.6 1.8 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Pex14_N PF04695.13 CDJ43913.1 - 9.4 6.9 14.7 18 6.0 14.8 1.6 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spc7 PF08317.11 CDJ43914.1 - 0.13 11.1 3.3 0.33 9.8 3.3 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein CtIP_N PF10482.9 CDJ43914.1 - 2.7 8.1 11.0 0.063 13.3 2.5 2.5 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain BBP1_C PF15272.6 CDJ43914.1 - 6.2 6.6 6.8 0.34 10.7 1.1 1.8 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Thiolase_N PF00108.23 CDJ43915.1 - 3.6e-77 259.2 1.2 7.1e-77 258.3 0.6 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CDJ43915.1 - 7.6e-49 164.5 0.3 7.6e-49 164.5 0.3 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CDJ43915.1 - 1.9e-05 24.4 1.0 6.1e-05 22.7 1.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 CDJ43915.1 - 0.018 15.2 0.0 0.06 13.5 0.0 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Uteroglobin PF01099.17 CDJ43915.1 - 0.059 13.7 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Uteroglobin family Ribosomal_60s PF00428.19 CDJ43915.1 - 0.26 11.9 15.6 0.075 13.6 9.6 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein DnaJ PF00226.31 CDJ43916.1 - 4.3e-23 81.2 0.2 7.4e-23 80.5 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Hist_deacetyl PF00850.19 CDJ43918.1 - 2.3e-65 221.1 1.6 2.8e-48 165.0 0.1 2.5 1 1 0 2 2 2 2 Histone deacetylase domain Muted PF14942.6 CDJ43919.1 - 0.024 15.0 0.2 0.037 14.4 0.2 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein EF-G-binding_N PF07299.11 CDJ43919.1 - 0.049 14.2 0.2 0.081 13.5 0.2 1.4 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal Phasin_2 PF09361.10 CDJ43919.1 - 0.084 13.1 6.9 0.24 11.7 6.0 2.0 1 1 0 1 1 1 0 Phasin protein TPR_2 PF07719.17 CDJ43920.1 - 0.00046 20.1 3.4 0.42 10.8 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ43920.1 - 0.00048 19.8 0.0 0.44 10.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 CDJ43920.1 - 0.0012 18.2 0.0 0.0048 16.3 0.0 2.1 1 0 0 1 1 1 1 SHNi-TPR DUF775 PF05603.12 CDJ43920.1 - 0.14 11.7 1.0 0.18 11.3 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF775) RLL PF10036.9 CDJ43920.1 - 0.26 11.1 3.7 0.35 10.7 3.7 1.2 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Sua5_yciO_yrdC PF01300.18 CDJ43921.1 - 3.2e-30 105.0 0.1 8.3e-30 103.6 0.1 1.7 1 1 0 1 1 1 1 Telomere recombination Serglycin PF04360.12 CDJ43921.1 - 0.011 15.6 11.2 0.057 13.4 2.8 3.0 3 0 0 3 3 3 0 Serglycin SR-25 PF10500.9 CDJ43921.1 - 0.47 10.0 24.6 0.043 13.4 3.2 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ43922.1 - 0.047 13.8 6.2 0.054 13.6 6.2 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PhnG PF06754.12 CDJ43922.1 - 0.13 12.2 6.3 0.14 12.1 6.3 1.1 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG Nbs1_C PF08599.10 CDJ43922.1 - 0.33 11.1 1.7 0.42 10.8 1.7 1.1 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 RNA_pol_A_CTD PF03118.15 CDJ43924.1 - 0.00099 18.8 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain Bul1_N PF04425.12 CDJ43924.1 - 0.0013 17.5 8.7 0.0018 17.1 8.7 1.1 1 0 0 1 1 1 1 Bul1 N terminus TFIIA PF03153.13 CDJ43924.1 - 0.0017 18.4 29.0 0.0022 18.1 29.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ43924.1 - 0.0049 17.1 3.5 0.0055 16.9 3.5 1.2 1 0 0 1 1 1 1 DDHD domain Presenilin PF01080.17 CDJ43924.1 - 0.0057 15.5 10.0 0.0067 15.3 10.0 1.1 1 0 0 1 1 1 1 Presenilin eIF-3_zeta PF05091.12 CDJ43924.1 - 0.0085 15.1 10.1 0.0097 14.9 10.1 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EPL1 PF10513.9 CDJ43924.1 - 0.012 16.0 5.0 0.012 16.0 5.0 1.5 2 0 0 2 2 1 0 Enhancer of polycomb-like RNA_pol_L PF01193.24 CDJ43924.1 - 0.015 14.7 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Exonuc_VII_L PF02601.15 CDJ43924.1 - 0.017 14.7 11.8 0.019 14.5 11.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAT1 PF09770.9 CDJ43924.1 - 0.024 13.0 20.0 0.026 12.8 20.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CSRNP_N PF16019.5 CDJ43924.1 - 0.031 14.2 7.3 0.059 13.3 7.3 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus MID_MedPIWI PF18296.1 CDJ43924.1 - 0.032 14.0 8.6 0.041 13.7 8.6 1.2 1 0 0 1 1 1 0 MID domain of medPIWI Sin_N PF04801.13 CDJ43924.1 - 0.032 13.4 17.0 0.039 13.2 17.0 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF2981 PF11200.8 CDJ43924.1 - 0.15 11.8 1.2 0.18 11.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Asparaginase_2 PF01112.18 CDJ43924.1 - 0.22 10.5 3.3 0.43 9.6 3.3 1.4 1 0 0 1 1 1 0 Asparaginase Dicty_REP PF05086.12 CDJ43924.1 - 0.26 9.2 3.1 0.3 9.0 3.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SLC12 PF03522.15 CDJ43924.1 - 0.37 9.8 9.2 0.45 9.5 9.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 CDJ43924.1 - 0.9 7.9 1.7 0.91 7.9 1.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Nop53 PF07767.11 CDJ43924.1 - 1.4 8.3 20.7 2.1 7.7 20.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ALMT PF11744.8 CDJ43924.1 - 1.7 7.4 7.1 2.1 7.1 7.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Menin PF05053.13 CDJ43924.1 - 2.1 6.6 7.4 2.6 6.3 7.4 1.1 1 0 0 1 1 1 0 Menin DUF4207 PF13904.6 CDJ43924.1 - 2.6 7.7 32.3 0.073 12.7 19.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) PTPRCAP PF15713.5 CDJ43924.1 - 2.7 8.2 18.7 6.1 7.1 18.7 1.6 1 1 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Membralin PF09746.9 CDJ43924.1 - 4.4 6.2 6.1 6.8 5.6 6.1 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF1980 PF09323.10 CDJ43924.1 - 5.7 6.8 6.5 7.4 6.4 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) UPF0560 PF10577.9 CDJ43924.1 - 7 5.0 20.3 11 4.4 20.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CLN3 PF02487.17 CDJ43924.1 - 7.9 5.4 8.3 12 4.8 8.3 1.2 1 0 0 1 1 1 0 CLN3 protein Peptidase_S49_N PF08496.10 CDJ43924.1 - 8.6 6.4 14.2 27 4.8 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal TERB2 PF15101.6 CDJ43924.1 - 8.6 6.4 19.9 0.6 10.1 15.2 1.4 2 0 0 2 2 1 0 Telomere-associated protein TERB2 VIT1 PF01988.19 CDJ43924.1 - 8.7 6.1 5.8 3.7 7.4 2.9 1.8 2 0 0 2 2 2 0 VIT family Med15 PF09606.10 CDJ43924.1 - 8.8 4.9 35.0 11 4.6 35.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hid1 PF12722.7 CDJ43924.1 - 9.4 4.2 12.8 11 4.0 12.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ABC_membrane PF00664.23 CDJ43925.1 - 1.3e-23 84.1 4.7 1.7e-23 83.6 4.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region RskA PF10099.9 CDJ43926.1 - 0.24 11.7 24.4 0.067 13.5 18.5 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA K_channel_TID PF07941.11 CDJ43926.1 - 1.2 9.6 17.8 0.072 13.6 11.6 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain TFIIA PF03153.13 CDJ43926.1 - 5.3 6.9 19.0 5.6 6.9 19.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 CDJ43928.1 - 0.54 9.4 6.7 0.62 9.2 6.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIF_alpha PF05793.12 CDJ43928.1 - 0.9 8.1 12.0 1.1 7.8 12.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FancD2 PF14631.6 CDJ43928.1 - 2.1 5.6 9.0 2.2 5.5 9.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Coilin_N PF15862.5 CDJ43928.1 - 4.2 7.2 11.8 6.1 6.6 11.8 1.4 1 0 0 1 1 1 0 Coilin N-terminus Sec62 PF03839.16 CDJ43928.1 - 4.9 6.6 6.6 5.9 6.3 6.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 MCM_bind PF09739.9 CDJ43928.1 - 8.9 4.6 11.4 9.8 4.5 11.4 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NPR3 PF03666.13 CDJ43928.1 - 9.4 4.9 11.3 10 4.8 11.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cas_DxTHG PF09455.10 CDJ43930.1 - 0.038 13.6 11.8 0.05 13.2 11.8 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family QRPTase_C PF01729.19 CDJ43930.1 - 0.1 12.3 2.6 0.25 11.1 2.6 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain GET2 PF08690.10 CDJ43930.1 - 9.4 5.8 22.1 16 5.1 22.1 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 PRP8_domainIV PF12134.8 CDJ43931.1 - 6.5e-105 349.9 0.1 7.5e-105 349.7 0.1 1.0 1 0 0 1 1 1 1 PRP8 domain IV core DUF4395 PF14340.6 CDJ43932.1 - 0.02 15.2 7.5 0.023 15.0 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) Polysacc_synt PF01943.17 CDJ43932.1 - 0.022 14.2 0.2 0.026 13.9 0.2 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MRP-S31 PF15433.6 CDJ43933.1 - 0.24 11.0 5.8 0.27 10.8 5.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Neur_chan_memb PF02932.16 CDJ43933.1 - 1.4 9.0 8.5 1.5 8.8 8.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF3_subunit PF08597.10 CDJ43933.1 - 1.7 8.5 10.0 2 8.2 10.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Spem1 PF15670.5 CDJ43933.1 - 2.2 7.8 11.6 2.6 7.6 11.6 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 SEEEED PF14797.6 CDJ43933.1 - 4.2 7.6 17.1 0.91 9.7 13.3 1.7 1 1 1 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Spt20 PF12090.8 CDJ43933.1 - 4.4 6.8 12.4 5.7 6.5 12.4 1.3 1 0 0 1 1 1 0 Spt20 family CDC45 PF02724.14 CDJ43933.1 - 4.5 5.5 13.7 5.1 5.3 13.7 1.0 1 0 0 1 1 1 0 CDC45-like protein NINJA_B PF16136.5 CDJ43933.1 - 5.8 7.3 18.6 11 6.4 18.3 1.5 1 1 1 2 2 2 0 Putative nuclear localisation signal ARGLU PF15346.6 CDJ43934.1 - 0.013 15.4 23.0 0.016 15.1 23.0 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF4834 PF16118.5 CDJ43934.1 - 0.17 12.9 6.0 0.19 12.7 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) 5_nucleotid PF05761.14 CDJ43934.1 - 0.19 10.6 9.4 0.23 10.3 9.4 1.0 1 0 0 1 1 1 0 5' nucleotidase family DUF3391 PF11871.8 CDJ43934.1 - 0.22 12.1 10.3 0.27 11.8 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF4092 PF13322.6 CDJ43934.1 - 0.36 10.7 3.2 0.46 10.3 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4092) LPD30 PF18850.1 CDJ43934.1 - 0.37 10.6 4.3 2.1 8.1 2.7 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 30 PepSY_TM PF03929.16 CDJ43934.1 - 1 8.9 2.4 1.2 8.7 2.4 1.0 1 0 0 1 1 1 0 PepSY-associated TM region DUF4407 PF14362.6 CDJ43934.1 - 1.8 7.8 13.0 2.1 7.6 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tho2 PF11262.8 CDJ43934.1 - 2.8 7.1 12.9 3.2 6.9 12.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Neur_chan_memb PF02932.16 CDJ43934.1 - 3.5 7.6 6.3 4 7.4 6.3 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EMC3_TMCO1 PF01956.16 CDJ43934.1 - 3.6 7.3 10.1 3.9 7.2 10.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Exonuc_VII_L PF02601.15 CDJ43934.1 - 4.4 6.8 14.8 5.3 6.5 14.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 CDJ43934.1 - 5.2 6.1 15.5 5.5 6.0 15.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Activator_LAG-3 PF11498.8 CDJ43934.1 - 8.8 5.2 28.7 10 5.0 28.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Androgen_recep PF02166.16 CDJ43935.1 - 0.045 12.6 10.5 0.055 12.3 10.5 1.2 1 0 0 1 1 1 0 Androgen receptor PIEZO PF15917.5 CDJ43935.1 - 0.064 12.7 11.7 0.079 12.4 11.7 1.2 1 0 0 1 1 1 0 Piezo TFIIA PF03153.13 CDJ43935.1 - 0.13 12.2 13.8 0.16 11.9 13.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hydin_ADK PF17213.3 CDJ43935.1 - 0.42 10.9 4.3 0.52 10.6 4.3 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA_23 PF13476.6 CDJ43935.1 - 5 7.6 12.3 5.9 7.3 12.3 1.1 1 0 0 1 1 1 0 AAA domain DUF2489 PF10675.9 CDJ43935.1 - 6.5 6.7 16.7 3.3 7.6 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) GHMP_kinases_N PF00288.26 CDJ43936.1 - 0.053 13.8 2.2 0.053 13.8 2.2 2.6 2 0 0 2 2 2 0 GHMP kinases N terminal domain DUF1980 PF09323.10 CDJ43936.1 - 0.098 12.6 1.0 0.21 11.5 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PrsW-protease PF13367.6 CDJ43936.1 - 0.29 10.6 6.8 0.48 9.8 3.2 2.2 2 0 0 2 2 2 0 PrsW family intramembrane metalloprotease DUF1180 PF06679.12 CDJ43936.1 - 1.2 9.6 18.4 1.5 9.2 13.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) PAT1 PF09770.9 CDJ43936.1 - 2.6 6.2 20.4 3.6 5.7 20.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ43936.1 - 4.3 7.1 10.0 6.1 6.6 9.4 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Pex14_N PF04695.13 CDJ43936.1 - 5.7 7.6 19.4 8.5 7.0 17.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA PF00004.29 CDJ43937.1 - 1.7e-18 67.3 0.0 2.5e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ43937.1 - 3.3e-08 33.6 0.0 6.8e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 CDJ43937.1 - 3.1e-07 29.6 0.0 3.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 CDJ43937.1 - 7.2e-07 29.8 0.1 4e-06 27.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ43937.1 - 2.2e-06 28.0 0.1 8.8e-05 22.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CDJ43937.1 - 3.9e-06 27.1 0.0 1.3e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CDJ43937.1 - 3.2e-05 23.7 0.0 4.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 CDJ43937.1 - 9e-05 22.3 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CDJ43937.1 - 0.00072 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CDJ43937.1 - 0.0012 18.8 0.1 0.016 15.1 0.1 2.2 1 1 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 CDJ43937.1 - 0.0022 17.9 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase NTPase_1 PF03266.15 CDJ43937.1 - 0.0025 17.7 0.0 0.032 14.1 0.0 2.3 1 1 1 2 2 2 1 NTPase AAA_18 PF13238.6 CDJ43937.1 - 0.0025 18.4 0.0 0.0052 17.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CDJ43937.1 - 0.0036 16.5 0.1 0.0084 15.3 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.22 CDJ43937.1 - 0.0044 17.4 0.0 0.0086 16.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 CDJ43937.1 - 0.0085 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 CDJ43937.1 - 0.0086 15.3 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_17 PF13207.6 CDJ43937.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CDJ43937.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CDJ43937.1 - 0.017 15.1 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ43937.1 - 0.023 15.2 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 CDJ43937.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CDJ43937.1 - 0.03 14.2 0.0 0.068 13.1 0.0 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain ResIII PF04851.15 CDJ43937.1 - 0.046 13.7 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 CDJ43937.1 - 0.067 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Torsin PF06309.11 CDJ43937.1 - 0.068 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA_19 PF13245.6 CDJ43937.1 - 0.074 13.4 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CDJ43937.1 - 0.08 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ParA PF10609.9 CDJ43937.1 - 0.097 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase TsaE PF02367.17 CDJ43937.1 - 0.11 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 CDJ43937.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 CDJ43937.1 - 0.14 11.9 0.4 0.31 10.7 0.0 1.8 3 0 0 3 3 1 0 AAA domain Mg_chelatase PF01078.21 CDJ43937.1 - 0.18 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.10 CDJ43937.1 - 0.2 11.1 0.0 0.56 9.6 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_15 PF13175.6 CDJ43937.1 - 0.21 11.2 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Fe_hyd_lg_C PF02906.14 CDJ43939.1 - 6.6e-07 29.2 0.0 9.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SR-25 PF10500.9 CDJ43939.1 - 1.5 8.3 4.5 2.3 7.8 4.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4667 PF15700.5 CDJ43940.1 - 0.042 13.9 14.1 0.069 13.2 14.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) DDHD PF02862.17 CDJ43940.1 - 0.042 14.0 3.2 0.054 13.7 3.2 1.2 1 0 0 1 1 1 0 DDHD domain DUF1635 PF07795.11 CDJ43940.1 - 0.05 13.5 15.6 0.083 12.7 15.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) MID_MedPIWI PF18296.1 CDJ43940.1 - 0.063 13.1 7.7 0.09 12.6 7.7 1.2 1 0 0 1 1 1 0 MID domain of medPIWI Lin-8 PF03353.15 CDJ43940.1 - 0.097 12.2 8.0 0.15 11.6 8.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF445 PF04286.12 CDJ43940.1 - 0.11 12.3 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Apt1 PF10351.9 CDJ43940.1 - 0.11 11.3 11.8 0.14 11.0 11.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Uds1 PF15456.6 CDJ43940.1 - 0.12 12.6 10.8 0.25 11.5 10.8 1.6 1 0 0 1 1 1 0 Up-regulated During Septation AATF-Che1 PF13339.6 CDJ43940.1 - 0.12 13.1 8.1 0.19 12.4 8.1 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Plexin_cytopl PF08337.12 CDJ43940.1 - 0.17 10.6 3.7 0.21 10.2 3.7 1.0 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain Vps39_1 PF10366.9 CDJ43940.1 - 0.26 11.6 1.2 0.5 10.7 1.2 1.6 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Presenilin PF01080.17 CDJ43940.1 - 0.32 9.7 5.2 0.39 9.4 5.2 1.2 1 0 0 1 1 1 0 Presenilin ATG16 PF08614.11 CDJ43940.1 - 0.5 10.6 18.4 0.063 13.5 13.2 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 CDJ43940.1 - 0.51 9.9 6.0 0.71 9.4 6.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CCDC24 PF15669.5 CDJ43940.1 - 0.63 9.9 18.9 0.16 11.8 15.0 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family PI3K_1B_p101 PF10486.9 CDJ43940.1 - 0.63 7.8 11.6 0.79 7.4 11.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit AF-4 PF05110.13 CDJ43940.1 - 1.4 6.9 26.7 1.8 6.6 26.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RSRP PF17069.5 CDJ43940.1 - 2.1 7.9 22.1 2.9 7.4 22.1 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 FAM199X PF15814.5 CDJ43940.1 - 2.3 7.2 16.6 0.26 10.3 12.2 1.5 2 0 0 2 2 2 0 Protein family FAM199X APG6_N PF17675.1 CDJ43940.1 - 3.1 8.3 16.2 17 5.9 4.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region SDP_N PF12278.8 CDJ43940.1 - 3.1 7.9 12.8 4.8 7.3 12.8 1.3 1 0 0 1 1 1 0 Sex determination protein N terminal DUF4552 PF15089.6 CDJ43940.1 - 3.3 6.7 17.3 4.2 6.3 17.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) Ctr PF04145.15 CDJ43940.1 - 3.8 8.1 5.2 7.2 7.2 4.8 1.6 2 0 0 2 2 2 0 Ctr copper transporter family CCDC106 PF15794.5 CDJ43940.1 - 3.8 7.2 13.7 7.2 6.2 13.7 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RAP1 PF07218.11 CDJ43940.1 - 4.4 5.5 12.9 5.4 5.2 12.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Miga PF10265.9 CDJ43940.1 - 5 6.0 12.4 6.9 5.5 12.4 1.1 1 0 0 1 1 1 0 Mitoguardin ALMT PF11744.8 CDJ43940.1 - 7.8 5.2 10.6 11 4.7 10.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Rtf2 PF04641.12 CDJ43940.1 - 8.6 5.6 8.3 13 5.0 8.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Syntaxin PF00804.25 CDJ43941.1 - 6.1e-06 26.0 5.7 8e-06 25.7 5.7 1.1 1 0 0 1 1 1 1 Syntaxin TAF PF02969.17 CDJ43941.1 - 0.062 13.5 0.7 0.26 11.5 0.1 2.2 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) DnaJ PF00226.31 CDJ43941.1 - 0.074 13.2 0.5 3.2 8.0 0.3 2.5 2 1 0 2 2 2 0 DnaJ domain SOG2 PF10428.9 CDJ43943.1 - 0.028 13.6 16.6 0.029 13.6 16.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Pol_alpha_B_N PF08418.10 CDJ43943.1 - 0.25 11.3 10.4 0.39 10.6 10.4 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Presenilin PF01080.17 CDJ43943.1 - 0.27 9.9 14.8 0.32 9.7 14.8 1.3 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CDJ43943.1 - 0.48 9.2 8.8 0.53 9.1 8.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain BAF1_ABF1 PF04684.13 CDJ43943.1 - 1.9 7.5 19.0 0.0056 15.8 9.8 1.6 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor NTP_transf_3 PF12804.7 CDJ43943.1 - 2.6 8.4 14.3 0.11 12.8 5.6 2.3 2 1 0 2 2 2 0 MobA-like NTP transferase domain Ndc1_Nup PF09531.10 CDJ43943.1 - 2.6 6.6 14.8 3.2 6.3 14.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Roughex PF06020.11 CDJ43943.1 - 4.5 6.3 13.9 9.3 5.2 13.9 1.5 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 CDJ43943.1 - 5.6 6.8 41.5 0.56 10.1 3.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Raftlin PF15250.6 CDJ43943.1 - 6.5 5.4 12.5 11 4.6 12.5 1.4 1 0 0 1 1 1 0 Raftlin XPG_N PF00752.17 CDJ43944.1 - 6.1e-08 33.1 0.0 9.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 XPG N-terminal domain CCDC24 PF15669.5 CDJ43944.1 - 1.2 9.0 5.9 3.4 7.5 5.9 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family TFIIA PF03153.13 CDJ43945.1 - 7 6.5 11.0 7.3 6.5 11.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ43946.1 - 3.4 7.2 11.7 7.6 6.1 5.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Dicer_dimer PF03368.14 CDJ43947.1 - 0.068 13.3 0.0 0.27 11.4 0.0 2.0 1 0 0 1 1 1 0 Dicer dimerisation domain TAXi_C PF14541.6 CDJ43948.1 - 0.00018 21.3 0.0 0.00018 21.3 0.0 1.0 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Lzipper-MIP1 PF14389.6 CDJ43949.1 - 0.0039 17.4 0.5 0.0079 16.5 0.5 1.5 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Peptidase_S64 PF08192.11 CDJ43949.1 - 0.0052 15.3 8.9 0.0062 15.1 8.9 1.0 1 0 0 1 1 1 1 Peptidase family S64 TMF_TATA_bd PF12325.8 CDJ43949.1 - 0.0065 16.7 1.1 0.014 15.6 1.1 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.15 CDJ43949.1 - 0.033 14.3 0.3 0.092 12.8 0.3 1.7 1 0 0 1 1 1 0 Basic region leucine zipper ABC_tran_CTD PF16326.5 CDJ43949.1 - 0.046 14.0 0.1 0.046 14.0 0.1 1.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain SPX PF03105.19 CDJ43949.1 - 0.16 11.8 12.5 0.19 11.6 12.5 1.1 1 0 0 1 1 1 0 SPX domain KIP1 PF07765.12 CDJ43949.1 - 0.2 11.8 0.1 0.37 11.0 0.1 1.4 1 0 0 1 1 1 0 KIP1-like protein JAKMIP_CC3 PF16034.5 CDJ43949.1 - 0.54 10.2 4.8 0.67 9.9 4.8 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain Apt1 PF10351.9 CDJ43949.1 - 0.79 8.5 12.1 0.89 8.3 12.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 CDJ43949.1 - 2.6 7.1 20.5 3 6.9 20.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Nnf1 PF03980.14 CDJ43949.1 - 3.8 7.9 10.2 36 4.8 10.2 2.1 1 1 0 1 1 1 0 Nnf1 SR-25 PF10500.9 CDJ43949.1 - 4.3 6.9 39.1 11 5.6 16.6 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 CDJ43949.1 - 4.7 5.6 21.8 7.1 5.1 21.8 1.3 1 1 0 1 1 1 0 Macoilin family DUF1645 PF07816.11 CDJ43951.1 - 0.002 18.8 19.6 0.07 13.7 5.6 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ43951.1 - 0.0084 15.8 7.9 0.34 10.5 0.8 2.2 2 0 0 2 2 2 2 Spt20 family SUIM_assoc PF16619.5 CDJ43951.1 - 0.015 15.3 16.1 0.26 11.4 0.3 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SNARE_assoc PF09335.11 CDJ43951.1 - 0.081 13.4 1.2 0.22 12.0 0.6 2.0 2 0 0 2 2 2 0 SNARE associated Golgi protein Lin-8 PF03353.15 CDJ43951.1 - 0.25 10.9 7.0 1.8 8.0 0.7 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ43951.1 - 3.1 7.4 47.2 0.058 13.0 6.4 4.0 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein SDP_N PF12278.8 CDJ43952.1 - 0.014 15.5 0.1 0.018 15.2 0.1 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal SR-25 PF10500.9 CDJ43952.1 - 0.46 10.1 14.4 0.64 9.6 14.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 CDJ43952.1 - 0.47 9.7 6.0 0.53 9.6 6.0 1.0 1 0 0 1 1 1 0 BUD22 RAP1 PF07218.11 CDJ43952.1 - 3.7 5.7 4.3 3.8 5.7 4.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BNIP3 PF06553.12 CDJ43952.1 - 9.6 5.8 11.2 1.8 8.2 6.5 1.8 1 1 1 2 2 2 0 BNIP3 BAF1_ABF1 PF04684.13 CDJ43953.1 - 6.4 5.7 8.8 7.4 5.5 8.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.8 CDJ43953.1 - 7.5 6.1 15.6 8.6 5.9 15.6 1.3 1 1 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ43954.1 - 0.00012 21.2 1.6 0.00016 20.8 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ43954.1 - 0.0012 18.6 7.9 0.0016 18.1 7.9 1.3 1 0 0 1 1 1 1 Spt20 family DUF5349 PF17298.2 CDJ43954.1 - 0.0098 15.7 1.0 0.0098 15.7 1.0 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5349) RAB3GAP2_N PF14655.6 CDJ43954.1 - 0.54 9.5 5.7 1.1 8.5 3.1 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SR-25 PF10500.9 CDJ43954.1 - 1 8.9 13.2 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Roughex PF06020.11 CDJ43954.1 - 7.8 5.5 6.9 11 5.0 6.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein SR-25 PF10500.9 CDJ43955.1 - 0.0012 18.5 16.1 0.01 15.5 5.0 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ43955.1 - 0.027 14.5 1.6 0.027 14.5 1.6 4.1 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 AF-4 PF05110.13 CDJ43955.1 - 0.43 8.6 26.7 0.19 9.8 3.7 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein NAM-associated PF14303.6 CDJ43955.1 - 0.67 10.7 7.7 5 7.8 2.5 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain IMUP PF15761.5 CDJ43955.1 - 1.2 9.8 18.7 0.82 10.4 5.8 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein CCSAP PF15748.5 CDJ43955.1 - 3.2 7.9 12.4 3.7 7.6 4.4 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated MscS_TM PF12794.7 CDJ43956.1 - 0.014 14.2 0.7 0.014 14.2 0.7 2.7 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 YpM PF09144.10 CDJ43957.1 - 0.095 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Yersinia pseudo-tuberculosis mitogen AAA_11 PF13086.6 CDJ43958.1 - 3.7 7.2 36.4 0.27 11.0 27.1 2.5 2 0 0 2 2 2 0 AAA domain DUF2722 PF10846.8 CDJ43959.1 - 0.00081 18.5 13.4 0.001 18.1 9.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DDOST_48kD PF03345.14 CDJ43959.1 - 0.028 13.2 4.1 0.037 12.9 4.1 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta WDCP PF15390.6 CDJ43959.1 - 0.054 11.9 4.6 0.07 11.5 4.6 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Serinc PF03348.15 CDJ43959.1 - 6.3 5.6 9.8 0.17 10.7 2.2 2.0 1 1 1 2 2 2 0 Serine incorporator (Serinc) DUF4834 PF16118.5 CDJ43959.1 - 6.9 7.7 9.9 0.95 10.5 2.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Adaptin_N PF01602.20 CDJ43960.1 - 0.0011 17.6 0.1 0.0011 17.6 0.1 1.7 2 0 0 2 2 2 1 Adaptin N terminal region Mo25 PF08569.11 CDJ43960.1 - 0.059 12.7 0.1 0.075 12.4 0.1 1.2 1 0 0 1 1 1 0 Mo25-like HEAT PF02985.22 CDJ43960.1 - 0.96 9.9 0.0 0.96 9.9 0.0 4.8 5 2 0 5 5 5 0 HEAT repeat RskA PF10099.9 CDJ43961.1 - 2.4e-06 28.0 5.8 2.4e-06 28.0 5.8 3.5 2 2 0 2 2 2 1 Anti-sigma-K factor rskA FHA PF00498.26 CDJ43961.1 - 0.00041 20.6 0.1 0.0017 18.7 0.0 2.0 2 0 0 2 2 2 1 FHA domain TFIIA PF03153.13 CDJ43961.1 - 0.18 11.8 73.7 0.028 14.4 24.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF5364 PF17322.2 CDJ43961.1 - 0.57 10.5 30.1 0.061 13.6 3.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5364) HATPase_c_5 PF14501.6 CDJ43961.1 - 1.2 9.1 4.6 2.7 8.0 4.6 1.6 1 0 0 1 1 1 0 GHKL domain DUF4746 PF15928.5 CDJ43961.1 - 2.5 7.4 17.7 3.6 6.9 6.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) AAA_11 PF13086.6 CDJ43961.1 - 4.1 7.1 31.2 0.023 14.5 4.0 2.2 2 0 0 2 2 2 0 AAA domain Atg14 PF10186.9 CDJ43962.1 - 0.00071 18.8 12.0 0.00085 18.5 12.0 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2052 PF09747.9 CDJ43962.1 - 0.082 13.0 8.0 0.11 12.6 8.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AAA_13 PF13166.6 CDJ43962.1 - 0.092 11.4 11.3 0.1 11.2 11.3 1.2 1 0 0 1 1 1 0 AAA domain GBP_C PF02841.14 CDJ43962.1 - 0.16 11.3 19.4 0.23 10.9 19.4 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Cob_adeno_trans PF01923.18 CDJ43962.1 - 0.19 11.8 7.1 0.28 11.3 7.1 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase V_ATPase_I PF01496.19 CDJ43962.1 - 0.23 9.3 5.4 0.26 9.2 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF812 PF05667.11 CDJ43962.1 - 0.91 8.3 13.2 1 8.2 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3584 PF12128.8 CDJ43962.1 - 1.2 6.5 20.4 1.5 6.3 20.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SOBP PF15279.6 CDJ43962.1 - 1.3 9.6 6.9 1.5 9.4 6.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Virul_Fac PF10139.9 CDJ43962.1 - 2.2 6.4 15.9 2.7 6.1 15.9 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor AATF-Che1 PF13339.6 CDJ43962.1 - 3.1 8.5 13.5 5.7 7.6 13.5 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor AAA_23 PF13476.6 CDJ43962.1 - 3.2 8.2 7.6 4.8 7.6 7.6 1.3 1 0 0 1 1 1 0 AAA domain Spt20 PF12090.8 CDJ43962.1 - 4.3 6.9 10.3 5.4 6.6 10.3 1.3 1 0 0 1 1 1 0 Spt20 family DUF2151 PF10221.9 CDJ43962.1 - 4.3 5.8 7.9 5.2 5.5 7.9 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator FemAB PF02388.16 CDJ43962.1 - 4.3 6.1 13.8 5.7 5.7 13.8 1.2 1 0 0 1 1 1 0 FemAB family DUF572 PF04502.13 CDJ43962.1 - 4.7 6.7 12.7 5.4 6.6 12.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Dynamitin PF04912.14 CDJ43962.1 - 6.5 6.0 19.3 9.7 5.4 19.3 1.3 1 1 0 1 1 1 0 Dynamitin LCIB_C_CA PF18599.1 CDJ43962.1 - 7.6 5.8 9.9 11 5.2 9.9 1.3 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases UPF0242 PF06785.11 CDJ43962.1 - 8.9 6.4 14.6 11 6.1 14.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MAD PF05557.13 CDJ43962.1 - 10 4.4 16.3 13 4.0 16.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein RIFIN PF02009.16 CDJ43963.1 - 5.6 6.8 6.3 5.6 6.8 6.3 1.0 1 0 0 1 1 1 0 Rifin TFIIA PF03153.13 CDJ43964.1 - 0.0013 18.8 17.8 0.0019 18.3 17.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ43964.1 - 0.0076 15.9 20.3 0.048 13.3 6.1 2.1 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 CDJ43964.1 - 0.19 10.6 16.8 0.17 10.8 4.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Roughex PF06020.11 CDJ43964.1 - 0.23 10.5 9.0 0.43 9.6 1.7 2.2 2 0 0 2 2 2 0 Drosophila roughex protein CagX PF03524.15 CDJ43964.1 - 0.45 10.2 3.0 4.3 7.0 0.2 2.1 2 0 0 2 2 2 0 Conjugal transfer protein SUIM_assoc PF16619.5 CDJ43964.1 - 1 9.5 30.0 3.3 7.8 10.5 3.7 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 IMUP PF15761.5 CDJ43964.1 - 2.1 9.1 17.4 2.1 9.0 6.4 2.7 3 0 0 3 3 3 0 Immortalisation up-regulated protein DUF4230 PF14014.6 CDJ43964.1 - 9.5 6.5 10.5 0.58 10.4 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) FHIPEP PF00771.20 CDJ43965.1 - 0.0072 14.9 2.6 0.011 14.3 2.6 1.4 1 0 0 1 1 1 1 FHIPEP family Peroxin-13_N PF04088.13 CDJ43965.1 - 0.072 13.4 1.3 0.4 11.0 0.2 2.5 3 0 0 3 3 3 0 Peroxin 13, N-terminal region DoxX PF07681.12 CDJ43965.1 - 0.11 13.1 4.5 0.1 13.2 1.9 2.3 1 1 1 2 2 2 0 DoxX BORG_CEP PF14957.6 CDJ43965.1 - 0.26 12.4 4.1 2 9.6 0.0 2.5 2 0 0 2 2 2 0 Cdc42 effector RskA PF10099.9 CDJ43966.1 - 1.2 9.4 17.7 0.5 10.7 6.4 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Adeno_PIX PF03955.14 CDJ43966.1 - 6.4 7.0 10.8 3.9 7.7 3.5 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) TERB2 PF15101.6 CDJ43967.1 - 0.12 12.4 1.6 0.13 12.3 0.1 1.7 1 1 1 2 2 2 0 Telomere-associated protein TERB2 IMUP PF15761.5 CDJ43968.1 - 0.029 15.1 6.8 0.038 14.7 6.8 1.1 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ43968.1 - 0.96 9.0 8.5 1.2 8.6 8.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LRR_6 PF13516.6 CDJ43969.1 - 0.024 14.7 1.1 0.41 10.8 0.6 2.5 2 0 0 2 2 2 0 Leucine Rich repeat DUF1908 PF08926.11 CDJ43970.1 - 0.078 12.0 1.4 0.089 11.9 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) SPX PF03105.19 CDJ43970.1 - 0.097 12.6 7.2 0.12 12.3 7.2 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 CDJ43970.1 - 0.34 9.4 3.5 0.43 9.1 3.5 1.3 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ43970.1 - 0.42 9.4 2.0 0.37 9.6 2.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nop16 PF09420.10 CDJ43971.1 - 8.5e-10 39.0 0.1 8.5e-10 39.0 0.1 1.9 2 1 0 2 2 2 1 Ribosome biogenesis protein Nop16 CCDC106 PF15794.5 CDJ43971.1 - 1.5 8.4 13.7 2.1 8.0 13.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Ribosomal_60s PF00428.19 CDJ43972.1 - 0.13 12.8 19.8 0.37 11.4 9.6 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2722 PF10846.8 CDJ43976.1 - 0.0071 15.3 6.3 0.0071 15.3 6.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) CTU2 PF10288.9 CDJ43976.1 - 3 8.1 12.2 1.9 8.7 5.0 2.3 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Autophagy_N PF03986.13 CDJ43977.1 - 3.1e-11 43.4 0.0 3.6e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain AlaDh_PNT_C PF01262.21 CDJ43978.1 - 1.5e-34 119.2 0.7 1.5e-34 119.2 0.7 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 CDJ43978.1 - 5.9e-24 84.9 0.5 3.7e-23 82.3 0.1 2.4 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, N-terminal domain NAD_binding_7 PF13241.6 CDJ43978.1 - 0.00043 20.7 0.0 0.0014 19.1 0.0 1.9 2 0 0 2 2 1 1 Putative NAD(P)-binding HI0933_like PF03486.14 CDJ43978.1 - 0.001 17.9 0.3 0.0019 17.0 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.18 CDJ43978.1 - 0.0018 18.2 0.5 0.0034 17.3 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 CDJ43978.1 - 0.002 17.4 1.0 0.0039 16.5 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDJ43978.1 - 0.006 15.9 0.6 0.011 15.0 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CDJ43978.1 - 0.0097 15.0 2.2 0.01 14.9 0.9 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CDJ43978.1 - 0.02 15.5 0.1 0.043 14.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDJ43978.1 - 0.028 13.5 1.5 0.064 12.3 1.5 1.6 1 0 0 1 1 1 0 FAD binding domain XdhC_C PF13478.6 CDJ43978.1 - 0.037 14.5 0.6 0.097 13.2 0.1 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_8 PF13450.6 CDJ43978.1 - 0.056 13.7 0.3 0.056 13.7 0.3 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Prefoldin PF02996.17 CDJ43978.1 - 0.086 12.8 0.4 0.17 11.8 0.4 1.5 1 0 0 1 1 1 0 Prefoldin subunit FAD_oxidored PF12831.7 CDJ43978.1 - 0.15 11.4 4.5 0.3 10.4 4.5 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase TolA_bind_tri PF16331.5 CDJ43978.1 - 5.9 7.0 13.6 0.36 10.9 4.0 2.8 3 0 0 3 3 3 0 TolA binding protein trimerisation Adeno_PIX PF03955.14 CDJ43978.1 - 7.6 6.8 17.0 0.058 13.6 7.2 2.7 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Methyltransf_25 PF13649.6 CDJ43979.1 - 3.2e-07 31.0 0.0 5.5e-05 23.8 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ43979.1 - 1e-06 29.3 0.0 0.00013 22.6 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ43979.1 - 2.1e-06 27.6 0.0 0.00074 19.3 0.0 3.6 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ43979.1 - 1.3e-05 25.9 0.0 0.0004 21.1 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Spermine_synth PF01564.17 CDJ43979.1 - 0.00012 21.6 0.0 0.0041 16.5 0.0 2.8 2 1 0 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 CDJ43979.1 - 0.00014 21.8 0.0 0.018 14.9 0.0 3.1 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ43979.1 - 0.17 11.8 0.0 0.5 10.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MmgE_PrpD PF03972.14 CDJ43980.1 - 3.7e-08 32.3 0.0 4.3e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family TFIIA PF03153.13 CDJ43981.1 - 1.3 8.9 6.1 1.4 8.8 6.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC2_membrane PF01061.24 CDJ43982.1 - 2.5e-22 79.3 15.8 3.7e-22 78.8 15.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CDJ43982.1 - 1.8e-19 70.6 0.6 2.1e-17 63.9 0.0 3.2 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CDJ43982.1 - 5.5e-07 29.7 0.8 7.1e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ43982.1 - 0.0047 16.4 0.0 0.025 14.0 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ43982.1 - 0.071 12.9 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CDJ43982.1 - 1.6 9.2 16.3 1.2 9.6 0.2 2.7 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 CDJ43982.1 - 2.4 7.2 15.6 5.1 6.1 15.6 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein EMC1_C PF07774.13 CDJ43983.1 - 2.1e-36 125.6 0.0 4e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CDJ43983.1 - 3.7e-09 36.5 12.3 1.6e-06 27.9 1.8 3.7 4 1 1 5 5 5 3 PQQ-like domain PQQ PF01011.21 CDJ43983.1 - 3.1e-05 23.7 0.8 0.83 9.7 0.0 3.9 4 0 0 4 4 4 2 PQQ enzyme repeat DUF2722 PF10846.8 CDJ43983.1 - 0.00038 19.6 4.3 0.00038 19.6 4.3 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Peroxin-22 PF12827.7 CDJ43984.1 - 0.023 14.6 0.0 0.025 14.5 0.0 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Hamartin PF04388.12 CDJ43986.1 - 0.032 12.9 12.2 0.038 12.7 12.2 1.3 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.9 CDJ43986.1 - 0.91 8.0 27.4 1.2 7.6 27.4 1.1 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CDJ43986.1 - 1.3 8.9 28.7 1.8 8.5 28.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Red1 PF07964.11 CDJ43986.1 - 7.7 4.6 25.7 10 4.2 25.7 1.0 1 0 0 1 1 1 0 Rec10 / Red1 BCL9 PF11502.8 CDJ43987.1 - 0.11 12.3 0.3 0.23 11.3 0.3 1.6 1 0 0 1 1 1 0 B-cell lymphoma 9 protein RAP1 PF07218.11 CDJ43988.1 - 0.0029 16.0 35.0 0.034 12.4 13.9 2.1 2 0 0 2 2 2 2 Rhoptry-associated protein 1 (RAP-1) Ribosomal_60s PF00428.19 CDJ43990.1 - 0.021 15.4 0.7 0.04 14.5 0.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4680 PF15730.5 CDJ43990.1 - 0.033 14.5 1.3 0.046 14.1 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4680) IstB_IS21 PF01695.17 CDJ43990.1 - 0.15 11.7 0.5 0.24 11.1 0.5 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Myosin_head PF00063.21 CDJ43991.1 - 6.4e-14 51.1 0.0 8.1e-14 50.8 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DUF533 PF04391.12 CDJ43991.1 - 0.011 15.3 0.3 0.011 15.3 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF533) eIF-6 PF01912.18 CDJ43993.1 - 5.5e-75 251.1 0.1 8e-75 250.6 0.1 1.2 1 0 0 1 1 1 1 eIF-6 family RNA_pol_A_bac PF01000.26 CDJ43994.1 - 2.2e-05 24.8 0.1 0.0012 19.2 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CDJ43994.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Spt20 PF12090.8 CDJ43994.1 - 2.2 7.8 14.9 0.28 10.8 6.4 2.3 2 0 0 2 2 2 0 Spt20 family SDA1 PF05285.12 CDJ43996.1 - 0.021 14.2 16.5 0.03 13.8 16.5 1.2 1 0 0 1 1 1 0 SDA1 LAP1C PF05609.12 CDJ43996.1 - 0.4 9.7 10.0 0.54 9.3 10.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2201_N PF13203.6 CDJ43996.1 - 0.54 9.8 3.7 2.3 7.7 3.7 1.9 1 1 0 1 1 1 0 Putative metallopeptidase domain SGT1 PF07093.11 CDJ43996.1 - 0.62 8.4 4.3 1.2 7.5 4.3 1.3 1 0 0 1 1 1 0 SGT1 protein Sec63 PF02889.16 CDJ43997.1 - 3.5e-08 32.9 0.4 9e-08 31.6 0.4 1.6 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.29 CDJ43997.1 - 1.9e-05 24.5 0.0 4.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ43997.1 - 0.0012 19.2 0.0 0.0046 17.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ43997.1 - 0.063 13.3 0.0 0.23 11.4 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TMEM154 PF15102.6 CDJ43997.1 - 0.064 13.2 1.6 0.093 12.6 0.1 2.0 2 0 0 2 2 2 0 TMEM154 protein family HHH_5 PF14520.6 CDJ43997.1 - 0.074 13.7 0.0 0.21 12.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Cdd1 PF11731.8 CDJ43997.1 - 0.13 12.5 0.1 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 Pathogenicity locus Orf78 PF06024.12 CDJ43997.1 - 1.2 9.4 4.1 0.43 10.9 0.7 2.0 2 0 0 2 2 2 0 Orf78 (ac78) FabA PF07977.13 CDJ43999.1 - 4.6e-28 97.6 0.0 5.7e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 CDJ43999.1 - 0.035 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain DUF508 PF04370.12 CDJ43999.1 - 0.12 12.1 0.2 0.16 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF1180 PF06679.12 CDJ43999.1 - 0.48 10.8 3.6 0.72 10.2 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PAT1 PF09770.9 CDJ44000.1 - 2 6.6 18.1 2.2 6.5 18.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FliJ PF02050.16 CDJ44000.1 - 4.8 7.4 31.3 6.8 6.9 31.3 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein Actin PF00022.19 CDJ44001.1 - 5.5e-26 91.1 0.0 1.1e-25 90.1 0.0 1.4 1 1 0 1 1 1 1 Actin EF-hand_8 PF13833.6 CDJ44002.1 - 2.8e-05 23.9 0.1 2.8e-05 23.9 0.1 1.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 CDJ44002.1 - 0.00027 21.3 0.7 0.00038 20.9 0.1 1.5 2 0 0 2 2 2 1 EF-hand domain pair DUF1840 PF08895.11 CDJ44002.1 - 0.0069 16.7 4.7 0.013 15.8 4.2 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF1840) GET2 PF08690.10 CDJ44002.1 - 0.012 15.3 3.7 0.014 15.0 3.7 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 S_100 PF01023.19 CDJ44002.1 - 0.016 14.9 0.7 0.052 13.3 0.6 1.9 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain MH2 PF03166.14 CDJ44002.1 - 0.017 15.4 0.6 0.018 15.3 0.6 1.1 1 0 0 1 1 1 0 MH2 domain EF-hand_1 PF00036.32 CDJ44002.1 - 0.032 13.8 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 CDJ44002.1 - 0.075 13.0 0.0 19 5.5 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain DUF1707 PF08044.11 CDJ44002.1 - 0.15 12.1 1.5 1.6 8.9 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1707) Peroxin-13_N PF04088.13 CDJ44002.1 - 0.41 10.9 2.7 0.54 10.5 2.7 1.3 1 1 0 1 1 1 0 Peroxin 13, N-terminal region Sec16 PF12932.7 CDJ44002.1 - 0.42 11.2 3.0 0.53 10.9 1.3 1.9 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region Spt20 PF12090.8 CDJ44002.1 - 0.82 9.2 15.6 1.1 8.9 15.6 1.2 1 0 0 1 1 1 0 Spt20 family Rsc14 PF08586.10 CDJ44002.1 - 3.2 8.6 6.9 8.1 7.3 4.5 2.0 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Med3 PF11593.8 CDJ44002.1 - 3.8 6.6 12.6 4.4 6.4 12.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Activator_LAG-3 PF11498.8 CDJ44002.1 - 5.9 5.8 21.6 6.9 5.5 21.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Vir_act_alpha_C PF10400.9 CDJ44004.1 - 0.052 14.2 3.2 0.48 11.1 0.1 2.5 2 0 0 2 2 2 0 Virulence activator alpha C-term GramPos_pilinD1 PF16555.5 CDJ44004.1 - 0.095 12.9 0.1 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain Spt20 PF12090.8 CDJ44004.1 - 0.28 10.8 3.6 2.7 7.6 0.5 2.2 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.9 CDJ44005.1 - 3.9 7.0 18.6 25 4.4 13.2 3.0 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein COX2 PF00116.20 CDJ44006.1 - 0.0064 16.4 0.1 0.014 15.2 0.1 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain AMA-1 PF02430.15 CDJ44007.1 - 4.9e-50 170.8 0.0 3e-44 151.8 0.0 2.2 1 1 1 2 2 2 2 Apical membrane antigen 1 DUF4366 PF14283.6 CDJ44007.1 - 0.036 14.1 3.2 0.27 11.3 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) DUF656 PF04920.12 CDJ44007.1 - 0.085 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF656) MMR1 PF08505.10 CDJ44007.1 - 0.84 9.9 8.9 1.3 9.2 8.9 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein EphA2_TM PF14575.6 CDJ44007.1 - 1.2 10.0 2.5 16 6.4 0.0 2.7 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SUIM_assoc PF16619.5 CDJ44007.1 - 6.7 6.9 19.7 5.5 7.1 6.3 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4653 PF15546.6 CDJ44009.1 - 5.6 6.5 9.4 0.66 9.5 5.4 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) DUF4653 PF15546.6 CDJ44010.1 - 0.48 10.0 5.4 0.87 9.2 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF4653 PF15546.6 CDJ44011.1 - 0.45 10.1 5.4 0.87 9.2 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF4653 PF15546.6 CDJ44012.1 - 0.37 10.4 4.9 0.73 9.4 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF4653 PF15546.6 CDJ44013.1 - 0.35 10.4 4.5 0.54 9.9 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF4653 PF15546.6 CDJ44014.1 - 0.5 10.0 5.4 0.98 9.0 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Phage-MuB_C PF09077.11 CDJ44015.1 - 0.0054 16.6 0.4 0.013 15.4 0.4 1.6 1 0 0 1 1 1 1 Mu B transposition protein, C terminal CNH PF00780.22 CDJ44015.1 - 0.15 11.6 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 CNH domain ER_lumen_recept PF00810.18 CDJ44016.1 - 1.6e-46 158.8 8.5 2.5e-46 158.1 8.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CDJ44016.1 - 0.1 12.4 11.9 0.15 11.8 0.2 4.4 4 1 1 5 5 5 0 PQ loop repeat SR-25 PF10500.9 CDJ44017.1 - 0.0053 16.4 15.8 0.0053 16.4 15.8 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF1645 PF07816.11 CDJ44017.1 - 0.26 11.8 20.1 0.52 10.9 20.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) Apt1 PF10351.9 CDJ44017.1 - 1.7 7.4 11.5 2.1 7.1 11.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peroxin-3 PF04882.12 CDJ44017.1 - 1.9 7.4 12.7 2.5 7.0 12.7 1.0 1 0 0 1 1 1 0 Peroxin-3 Plasmodium_Vir PF05795.11 CDJ44017.1 - 2 7.8 4.2 2.2 7.6 4.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein EBP50_C PF09007.11 CDJ44017.1 - 2.1 9.3 14.7 0.41 11.6 2.5 2.1 2 0 0 2 2 2 0 EBP50, C-terminal Spt20 PF12090.8 CDJ44017.1 - 4.9 6.7 16.9 8.5 5.9 16.9 1.4 1 0 0 1 1 1 0 Spt20 family RAP1 PF07218.11 CDJ44017.1 - 8.5 4.5 11.8 9 4.4 11.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PA14 PF07691.12 CDJ44018.1 - 7.2e-17 61.6 0.0 2.2e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 PA14 domain RNA_pol_Rpc4 PF05132.14 CDJ44018.1 - 0.028 14.8 1.0 0.028 14.8 1.0 2.0 3 0 0 3 3 3 0 RNA polymerase III RPC4 DUF4366 PF14283.6 CDJ44018.1 - 4 7.5 4.6 17 5.4 4.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Aldedh PF00171.22 CDJ44019.1 - 5.1e-25 87.9 0.0 5.6e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PNP_UDP_1 PF01048.20 CDJ44020.1 - 5.1e-20 71.7 0.0 5.8e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily HALZ PF02183.18 CDJ44021.1 - 0.00014 22.0 0.3 0.00014 22.0 0.3 8.4 7 2 2 9 9 9 2 Homeobox associated leucine zipper SUIM_assoc PF16619.5 CDJ44021.1 - 0.0022 18.0 2.3 0.0022 18.0 2.3 11.4 6 3 3 9 9 9 2 Unstructured region C-term to UIM in Ataxin3 Helicase_C PF00271.31 CDJ44022.1 - 9.2e-15 54.9 0.0 1.7e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_2 PF07724.14 CDJ44023.1 - 2.1e-38 132.1 0.4 1.1e-36 126.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CDJ44023.1 - 5.1e-21 74.6 0.3 5.1e-21 74.6 0.3 2.5 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 CDJ44023.1 - 8.8e-15 54.5 0.0 3e-14 52.8 0.0 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CDJ44023.1 - 6.3e-08 32.7 0.1 3.3e-07 30.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ44023.1 - 2.4e-07 31.2 0.0 7.3e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ44023.1 - 7.8e-07 28.9 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Torsin PF06309.11 CDJ44023.1 - 0.00034 20.7 0.0 0.00098 19.2 0.0 1.7 1 0 0 1 1 1 1 Torsin Zeta_toxin PF06414.12 CDJ44023.1 - 0.0005 19.4 0.0 0.0013 18.0 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 CDJ44023.1 - 0.00054 20.2 4.8 0.48 10.7 0.2 3.9 3 2 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CDJ44023.1 - 0.001 19.6 0.0 0.018 15.6 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 CDJ44023.1 - 0.0011 19.4 0.0 0.0011 19.4 0.0 2.8 4 1 0 4 4 3 1 AAA ATPase domain DNA_pol3_delta2 PF13177.6 CDJ44023.1 - 0.0083 15.9 0.1 0.032 14.0 0.0 2.2 2 1 0 2 2 2 1 DNA polymerase III, delta subunit ResIII PF04851.15 CDJ44023.1 - 0.021 14.9 0.0 0.76 9.8 0.0 2.6 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 CDJ44023.1 - 0.027 14.4 0.0 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 CDJ44023.1 - 0.03 14.7 0.1 0.21 12.0 0.2 2.4 2 1 0 2 2 1 0 RNA helicase AAA_14 PF13173.6 CDJ44023.1 - 0.031 14.3 0.0 0.099 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CDJ44023.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Roc PF08477.13 CDJ44023.1 - 0.046 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 CDJ44023.1 - 0.055 12.6 0.0 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 CDJ44023.1 - 0.063 13.5 0.1 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CDJ44023.1 - 0.095 13.2 0.0 0.23 12.0 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CDJ44023.1 - 0.097 12.8 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CDJ44023.1 - 0.11 12.2 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 CDJ44023.1 - 0.12 12.1 0.0 0.76 9.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 CDJ44023.1 - 0.13 12.2 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 CDJ44023.1 - 0.14 12.2 1.2 0.78 9.8 0.6 2.6 1 1 1 2 2 2 0 Helicase HerA, central domain MutS_III PF05192.18 CDJ44024.1 - 2.4e-09 37.7 4.1 9.8e-09 35.7 4.1 2.0 1 1 0 1 1 1 1 MutS domain III K_channel_TID PF07941.11 CDJ44025.1 - 0.019 15.4 4.5 0.019 15.4 4.5 1.7 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain ARF7EP_C PF14949.6 CDJ44026.1 - 0.047 14.3 4.7 0.065 13.9 4.7 1.3 1 0 0 1 1 1 0 ARF7 effector protein C-terminus TFIIA PF03153.13 CDJ44026.1 - 0.85 9.5 22.2 1 9.3 22.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3446 PF11928.8 CDJ44026.1 - 1 9.7 8.5 1.7 9.0 1.7 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain Lin-8 PF03353.15 CDJ44026.1 - 1.9 8.0 11.2 2.1 7.8 11.2 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist LMBR1 PF04791.16 CDJ44026.1 - 2.2 7.1 4.0 2.4 6.9 4.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 CDJ44026.1 - 3.5 6.3 11.6 3.9 6.1 11.6 1.1 1 0 0 1 1 1 0 Presenilin SUZ PF12752.7 CDJ44027.1 - 0.0051 17.5 1.3 0.025 15.4 0.6 2.0 2 0 0 2 2 2 1 SUZ domain TraU PF06834.11 CDJ44027.1 - 0.23 10.7 0.5 0.25 10.6 0.5 1.2 1 0 0 1 1 1 0 TraU protein SR-25 PF10500.9 CDJ44027.1 - 0.84 9.2 14.6 0.05 13.2 9.7 1.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ44028.1 - 4.1e-05 23.3 15.9 4.1e-05 23.3 15.9 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF4667 PF15700.5 CDJ44028.1 - 0.00011 22.3 1.8 0.00016 21.9 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) FAM220 PF15487.6 CDJ44028.1 - 0.0047 16.6 0.3 0.0047 16.6 0.3 1.4 2 0 0 2 2 2 1 FAM220 family Sporozoite_P67 PF05642.11 CDJ44028.1 - 0.085 10.9 5.8 0.099 10.7 5.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SPX PF03105.19 CDJ44028.1 - 0.24 11.3 8.9 0.32 10.9 8.9 1.1 1 0 0 1 1 1 0 SPX domain AF-4 PF05110.13 CDJ44028.1 - 0.33 9.0 23.2 0.51 8.4 23.2 1.3 1 1 0 1 1 1 0 AF-4 proto-oncoprotein Chorion_2 PF03964.15 CDJ44028.1 - 0.76 10.6 13.6 1.5 9.7 10.7 2.3 2 0 0 2 2 2 0 Chorion family 2 DUF1645 PF07816.11 CDJ44028.1 - 1.2 9.7 20.3 2.1 8.9 20.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) ANAPC1 PF12859.7 CDJ44028.1 - 7.6 7.1 13.9 0.17 12.5 1.5 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 1 DUF3094 PF11293.8 CDJ44029.1 - 0.038 13.7 0.4 0.077 12.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Borrelia_P83 PF05262.11 CDJ44029.1 - 2.5 6.5 6.4 4.4 5.7 6.4 1.3 1 1 0 1 1 1 0 Borrelia P83/100 protein Cullin PF00888.22 CDJ44030.1 - 1.1e-87 295.1 0.0 4.5e-87 293.1 0.0 1.8 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDJ44030.1 - 6.4e-22 77.4 0.0 1.5e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain DHHC PF01529.20 CDJ44031.1 - 0.00085 19.4 0.6 0.0013 18.9 0.6 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Spt20 PF12090.8 CDJ44031.1 - 0.088 12.4 10.3 0.14 11.7 10.3 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ44031.1 - 0.51 10.4 12.6 1.3 9.2 12.6 1.8 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 FAM176 PF14851.6 CDJ44031.1 - 7.6 6.2 10.1 5.6 6.6 0.1 2.5 3 0 0 3 3 3 0 FAM176 family 14-3-3 PF00244.20 CDJ44032.1 - 7e-37 127.1 0.0 7.8e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 14-3-3 protein PG_binding_1 PF01471.18 CDJ44032.1 - 0.057 13.6 0.1 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Putative peptidoglycan binding domain CSTF_C PF14304.6 CDJ44032.1 - 0.087 12.4 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal TPR_14 PF13428.6 CDJ44032.1 - 0.21 12.5 7.0 1.3 10.1 0.6 2.9 2 2 1 3 3 3 0 Tetratricopeptide repeat Adap_comp_sub PF00928.21 CDJ44033.1 - 5.5e-05 22.7 0.0 5.9e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF508 PF04370.12 CDJ44033.1 - 0.079 12.7 2.0 0.1 12.3 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF508) IMUP PF15761.5 CDJ44033.1 - 0.16 12.7 6.4 0.22 12.2 6.4 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF5470 PF17564.2 CDJ44033.1 - 0.71 10.1 6.8 1.3 9.3 6.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5470) SR-25 PF10500.9 CDJ44033.1 - 0.8 9.3 6.9 0.93 9.1 6.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2572 PF10833.8 CDJ44034.1 - 0.55 10.0 5.2 0.73 9.6 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) DUF702 PF05142.12 CDJ44034.1 - 3.6 8.1 8.9 5 7.6 8.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF702) Mcm10 PF09332.11 CDJ44034.1 - 8 5.8 12.5 9.5 5.5 12.5 1.0 1 0 0 1 1 1 0 Mcm10 replication factor Spt20 PF12090.8 CDJ44034.1 - 8.3 5.9 13.7 10 5.6 13.7 1.1 1 0 0 1 1 1 0 Spt20 family GTP_EFTU PF00009.27 CDJ44035.1 - 1.4e-53 181.3 0.0 2.1e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDJ44035.1 - 2.2e-40 137.4 0.0 7e-40 135.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDJ44035.1 - 1.4e-15 57.4 0.6 4.9e-15 55.7 0.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ44035.1 - 0.00026 21.1 0.0 0.028 14.5 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase NIF3 PF01784.18 CDJ44035.1 - 0.00027 20.7 0.1 0.00047 19.9 0.1 1.4 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) GTP_EFTU_D4 PF14578.6 CDJ44035.1 - 0.05 13.5 0.4 0.05 13.5 0.4 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 4 DTHCT PF08070.11 CDJ44036.1 - 5.2 7.9 10.7 15 6.4 1.5 2.8 1 1 0 2 2 2 0 DTHCT (NUC029) region DUF1635 PF07795.11 CDJ44038.1 - 1.3 8.8 19.1 0.49 10.2 6.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) SUIM_assoc PF16619.5 CDJ44038.1 - 6 7.0 25.3 0.056 13.5 1.5 3.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Activator_LAG-3 PF11498.8 CDJ44040.1 - 0.16 10.9 26.8 0.25 10.3 26.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Latrophilin PF02354.16 CDJ44040.1 - 0.84 8.6 7.5 1.3 8.0 7.5 1.3 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region AAA_23 PF13476.6 CDJ44040.1 - 4.2 7.8 10.0 6.2 7.3 10.0 1.2 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.9 CDJ44040.1 - 5.4 6.6 23.1 0.012 15.3 8.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein LMBR1 PF04791.16 CDJ44040.1 - 5.9 5.7 4.9 8 5.2 4.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Phage_Gp23 PF10669.9 CDJ44040.1 - 9.7 6.5 11.0 17 5.8 11.0 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) CrgA PF06781.12 CDJ44041.1 - 0.33 11.0 0.1 0.33 11.0 0.1 3.5 3 1 0 3 3 3 0 Cell division protein CrgA OsmC PF02566.19 CDJ44042.1 - 0.082 13.4 3.6 0.075 13.5 2.5 1.4 1 1 0 1 1 1 0 OsmC-like protein Phos_pyr_kin PF08543.12 CDJ44043.1 - 6e-07 29.1 0.0 1e-05 25.0 0.0 2.6 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CDJ44043.1 - 6.7e-05 22.3 1.9 0.084 12.2 0.0 3.3 2 1 1 3 3 3 2 pfkB family carbohydrate kinase KAsynt_C_assoc PF16197.5 CDJ44043.1 - 0.013 15.9 0.1 0.013 15.9 0.1 2.7 3 1 0 3 3 3 0 Ketoacyl-synthetase C-terminal extension RskA PF10099.9 CDJ44045.1 - 0.0011 19.3 0.3 0.0011 19.3 0.3 7.4 4 2 3 7 7 6 2 Anti-sigma-K factor rskA DUF3682 PF12446.8 CDJ44045.1 - 0.0029 18.1 9.8 0.0029 18.1 9.8 8.6 6 2 2 8 8 3 1 Protein of unknown function (DUF3682) Ribosomal_60s PF00428.19 CDJ44045.1 - 0.0086 16.7 1.6 0.0086 16.7 1.6 6.4 5 2 1 6 6 4 1 60s Acidic ribosomal protein Orf78 PF06024.12 CDJ44045.1 - 0.033 14.5 0.1 0.033 14.5 0.1 5.4 4 1 2 6 6 6 0 Orf78 (ac78) DUF4366 PF14283.6 CDJ44045.1 - 0.043 13.9 0.1 0.043 13.9 0.1 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4366) HA2 PF04408.23 CDJ44045.1 - 0.045 14.0 0.7 0.045 14.0 0.7 5.2 4 1 0 4 4 4 0 Helicase associated domain (HA2) DUF846 PF05832.12 CDJ44045.1 - 0.062 13.3 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) Vac7 PF12751.7 CDJ44045.1 - 0.83 9.0 14.1 0.02 14.4 6.4 2.1 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 DUF4064 PF13273.6 CDJ44045.1 - 1.3 9.4 0.0 1.3 9.4 0.0 4.3 6 0 0 6 6 5 0 Protein of unknown function (DUF4064) DUF3899 PF13038.6 CDJ44045.1 - 1.6 9.3 0.0 1.6 9.3 0.0 3.1 4 0 0 4 4 3 0 Domain of unknown function (DUF3899) LMBR1 PF04791.16 CDJ44045.1 - 7.1 5.4 18.8 0.0047 15.9 6.2 2.0 3 0 0 3 3 3 0 LMBR1-like membrane protein Form_Nir_trans PF01226.17 CDJ44046.1 - 3.6e-64 216.3 16.0 6.6e-64 215.5 16.0 1.4 1 0 0 1 1 1 1 Formate/nitrite transporter ABC_tran PF00005.27 CDJ44046.1 - 2.5e-12 47.5 0.6 5.9e-09 36.6 0.2 2.7 2 1 1 3 3 3 2 ABC transporter ABC2_membrane PF01061.24 CDJ44046.1 - 0.0016 17.9 10.2 0.0016 17.9 10.2 2.9 2 2 0 2 2 2 1 ABC-2 type transporter RsgA_GTPase PF03193.16 CDJ44046.1 - 0.0025 17.7 0.2 0.0047 16.8 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CDJ44046.1 - 0.14 11.9 0.2 0.33 10.7 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CDJ44046.1 - 0.14 12.6 0.2 0.27 11.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CDJ44046.1 - 0.21 11.7 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Uso1_p115_C PF04871.13 CDJ44046.1 - 0.76 10.2 4.7 1.6 9.1 4.7 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region GTP_EFTU PF00009.27 CDJ44047.1 - 5e-47 160.0 0.0 6.3e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ44047.1 - 1.3e-06 28.5 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDJ44047.1 - 0.003 17.6 0.0 0.15 12.1 0.0 2.2 1 1 1 2 2 2 1 Dynamin family SRPRB PF09439.10 CDJ44047.1 - 0.0066 15.9 0.0 0.32 10.4 0.0 2.4 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Septin PF00735.18 CDJ44047.1 - 0.078 12.2 0.0 0.62 9.3 0.0 1.9 1 1 0 1 1 1 0 Septin RskA PF10099.9 CDJ44047.1 - 0.76 10.0 32.4 0.17 12.2 16.5 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA F_bP_aldolase PF01116.20 CDJ44047.1 - 6.4 6.2 8.7 0.16 11.4 1.3 1.8 2 0 0 2 2 2 0 Fructose-bisphosphate aldolase class-II PSII_BNR PF14870.6 CDJ44049.1 - 8.6e-05 21.9 0.1 0.00011 21.6 0.1 1.1 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 Reg_prop PF07494.11 CDJ44049.1 - 0.049 13.9 0.0 15 6.2 0.0 2.5 2 0 0 2 2 2 0 Two component regulator propeller Ribosomal_60s PF00428.19 CDJ44049.1 - 0.056 14.0 5.1 0.056 14.0 5.1 1.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Tachylectin PF14517.6 CDJ44049.1 - 0.062 12.8 0.2 0.18 11.3 0.2 1.7 2 0 0 2 2 2 0 Tachylectin RED_N PF07808.13 CDJ44050.1 - 1.4e-19 70.6 21.5 2.8e-18 66.4 16.7 3.5 2 1 0 2 2 2 1 RED-like protein N-terminal region SUIM_assoc PF16619.5 CDJ44050.1 - 0.11 12.6 15.7 0.41 10.7 2.3 3.9 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PIH1 PF08190.12 CDJ44051.1 - 1.9e-10 40.4 0.2 1.3e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 PIH1 N-terminal domain Acyltransferase PF01553.21 CDJ44052.1 - 3.7e-15 55.7 0.0 7.6e-09 35.3 0.0 2.6 2 0 0 2 2 2 2 Acyltransferase SOG2 PF10428.9 CDJ44052.1 - 0.021 14.0 35.7 0.035 13.3 35.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF872 PF05915.12 CDJ44052.1 - 2.2 8.4 3.5 1.5 9.0 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DEAD PF00270.29 CDJ44053.1 - 8e-34 116.9 0.0 1.6e-33 115.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ44053.1 - 3.6e-18 65.9 0.0 6.9e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 CDJ44053.1 - 5.9e-08 32.9 0.1 1.5e-07 31.6 0.1 1.7 1 1 0 1 1 1 1 SPRY domain ResIII PF04851.15 CDJ44053.1 - 0.041 13.9 0.0 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IMUP PF15761.5 CDJ44053.1 - 0.17 12.5 10.5 0.15 12.7 0.3 2.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF4366 PF14283.6 CDJ44056.1 - 0.055 13.5 0.4 0.094 12.8 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) NBD_C PF17042.5 CDJ44056.1 - 0.2 12.2 6.7 0.25 11.8 6.7 1.1 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain Tic110 PF16940.5 CDJ44056.1 - 0.58 8.6 5.8 0.57 8.6 5.8 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter RskA PF10099.9 CDJ44056.1 - 1.2 9.4 24.6 1.9 8.8 24.6 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Calici_coat PF00915.20 CDJ44056.1 - 3.3 6.5 5.4 3.6 6.4 5.4 1.1 1 0 0 1 1 1 0 Calicivirus coat protein RskA PF10099.9 CDJ44057.1 - 0.0011 19.3 9.8 0.0011 19.3 9.8 5.1 1 1 1 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ44058.1 - 0.005 16.9 6.6 0.005 16.9 6.6 3.0 2 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit DUF3446 PF11928.8 CDJ44058.1 - 0.01 16.1 3.3 0.01 16.1 3.3 7.5 5 3 2 8 8 8 0 Early growth response N-terminal domain DUF2207 PF09972.9 CDJ44058.1 - 0.21 10.3 10.0 0.084 11.6 7.0 1.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) PIG-U PF06728.13 CDJ44058.1 - 3.4 6.6 5.4 1.3 7.9 2.8 1.6 2 0 0 2 2 2 0 GPI transamidase subunit PIG-U DUF4834 PF16118.5 CDJ44058.1 - 6.2 7.9 24.4 1.4 10.0 3.2 4.9 6 0 0 6 6 6 0 Domain of unknown function (DUF4834) SPX PF03105.19 CDJ44058.1 - 7.4 6.4 33.0 0.026 14.4 8.3 3.4 3 1 0 3 3 3 0 SPX domain PMI_typeI PF01238.21 CDJ44059.1 - 7.9e-53 180.0 27.6 2.3e-28 99.5 11.4 4.6 4 1 1 5 5 5 3 Phosphomannose isomerase type I Sin_N PF04801.13 CDJ44059.1 - 6.7e-07 28.9 12.8 6.7e-07 28.9 12.8 3.9 2 1 1 3 3 3 1 Sin-like protein conserved region Spt20 PF12090.8 CDJ44059.1 - 2.2e-05 24.2 5.4 2.2e-05 24.2 5.4 7.4 4 2 1 5 5 5 1 Spt20 family DUF4238 PF14022.6 CDJ44059.1 - 0.04 13.4 7.0 0.38 10.2 5.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4238) GCD14 PF08704.10 CDJ44059.1 - 5.8 6.5 14.6 0.055 13.1 0.4 3.5 3 0 0 3 3 3 0 tRNA methyltransferase complex GCD14 subunit PAM2 PF07145.15 CDJ44061.1 - 0.00022 20.7 1.0 0.00022 20.7 1.0 2.1 2 0 0 2 2 2 1 Ataxin-2 C-terminal region RskA PF10099.9 CDJ44061.1 - 3.9 7.7 0.0 3.9 7.7 0.0 8.2 2 2 4 6 6 6 0 Anti-sigma-K factor rskA NYD-SP28_assoc PF14775.6 CDJ44062.1 - 0.05 13.7 1.1 0.06 13.5 1.1 1.1 1 0 0 1 1 1 0 Sperm tail C-terminal domain SR-25 PF10500.9 CDJ44062.1 - 0.07 12.7 9.8 0.075 12.6 9.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 CDJ44062.1 - 0.13 10.7 2.5 0.13 10.6 2.5 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) IMUP PF15761.5 CDJ44062.1 - 0.22 12.2 7.2 0.23 12.2 7.2 1.1 1 0 0 1 1 1 0 Immortalisation up-regulated protein Ribonuc_red_sm PF00268.21 CDJ44063.1 - 2.6e-47 161.6 0.0 3e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Proteasome PF00227.26 CDJ44064.1 - 2e-24 86.1 0.0 2.6e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pyr_redox_2 PF07992.14 CDJ44065.1 - 2.3e-33 115.7 0.1 1.4e-32 113.1 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ44065.1 - 7.2e-23 80.9 0.4 2e-12 47.3 0.0 2.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDJ44065.1 - 2.9e-15 56.6 0.1 6.4e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Spt20 PF12090.8 CDJ44065.1 - 0.00076 19.2 1.3 0.0012 18.5 1.3 1.3 1 0 0 1 1 1 1 Spt20 family DUF3446 PF11928.8 CDJ44065.1 - 0.00086 19.6 7.8 0.0018 18.5 7.8 1.5 1 0 0 1 1 1 1 Early growth response N-terminal domain Lin-8 PF03353.15 CDJ44065.1 - 0.0064 16.1 2.7 0.0091 15.6 2.7 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Chorion_2 PF03964.15 CDJ44065.1 - 0.013 16.3 1.8 0.18 12.7 0.6 2.2 2 0 0 2 2 2 0 Chorion family 2 SpoVR PF04293.13 CDJ44065.1 - 0.028 13.1 2.3 0.026 13.2 0.8 1.6 2 0 0 2 2 2 0 SpoVR like protein AF-4 PF05110.13 CDJ44065.1 - 0.042 11.9 13.8 0.057 11.5 13.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Androgen_recep PF02166.16 CDJ44065.1 - 0.046 12.6 3.1 0.086 11.7 3.1 1.4 1 0 0 1 1 1 0 Androgen receptor DUF1635 PF07795.11 CDJ44065.1 - 0.089 12.6 7.8 0.14 12.0 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF1645 PF07816.11 CDJ44065.1 - 0.11 13.1 9.9 0.21 12.2 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) CDK2AP PF09806.9 CDJ44065.1 - 0.12 12.5 4.8 0.21 11.6 4.8 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2722 PF10846.8 CDJ44065.1 - 0.16 10.9 8.4 0.23 10.4 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) GREB1 PF15782.5 CDJ44065.1 - 0.24 8.5 5.3 0.31 8.1 5.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4692 PF15763.5 CDJ44065.1 - 0.29 11.6 5.3 0.074 13.5 2.2 1.5 2 0 0 2 2 1 0 Regulator of human erythroid cell expansion (RHEX) Peroxin-3 PF04882.12 CDJ44065.1 - 0.46 9.4 6.5 0.7 8.8 6.5 1.2 1 0 0 1 1 1 0 Peroxin-3 SIT PF15330.6 CDJ44065.1 - 0.84 10.1 6.1 1.5 9.3 6.1 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DnaJ-X PF14308.6 CDJ44066.1 - 4.1e-38 130.9 2.7 4.6e-38 130.8 2.7 1.0 1 0 0 1 1 1 1 X-domain of DnaJ-containing Chorismate_synt PF01264.21 CDJ44067.1 - 7.5e-87 291.1 0.0 2.2e-82 276.4 0.0 2.4 2 1 0 2 2 2 2 Chorismate synthase SPX PF03105.19 CDJ44067.1 - 2.8e-05 24.2 15.2 2.8e-05 24.2 15.2 1.4 2 0 0 2 2 2 1 SPX domain DDHD PF02862.17 CDJ44067.1 - 0.018 15.2 13.5 0.44 10.7 6.5 2.9 3 1 0 3 3 3 0 DDHD domain Ferlin_C PF16165.5 CDJ44067.1 - 0.58 10.1 3.9 5.5 6.9 0.2 2.2 2 0 0 2 2 2 0 Ferlin C-terminus DUF4228 PF14009.6 CDJ44067.1 - 1 9.7 14.0 1.9 8.9 5.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4228) Apt1 PF10351.9 CDJ44067.1 - 4.1 6.1 24.5 1.5 7.6 18.9 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Apc15p PF05841.11 CDJ44067.1 - 4.9 8.0 20.9 15 6.4 3.6 3.0 2 0 0 2 2 2 0 Apc15p protein Ctr PF04145.15 CDJ44067.1 - 5.1 7.7 7.6 21 5.7 0.3 2.5 2 0 0 2 2 2 0 Ctr copper transporter family Pex14_N PF04695.13 CDJ44067.1 - 5.8 7.6 19.9 3.2 8.4 4.7 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MOFRL PF05161.13 CDJ44068.1 - 0.45 10.7 5.8 0.52 10.5 5.8 1.1 1 0 0 1 1 1 0 MOFRL family DUF2339 PF10101.9 CDJ44070.1 - 1.7 7.1 15.2 1.9 7.0 15.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) RIFIN PF02009.16 CDJ44070.1 - 3.7 7.4 7.8 4.2 7.2 7.8 1.2 1 0 0 1 1 1 0 Rifin Dehydrin PF00257.19 CDJ44070.1 - 7.4 7.1 9.1 8.7 6.9 9.1 1.2 1 0 0 1 1 1 0 Dehydrin DUF4781 PF16013.5 CDJ44070.1 - 9.2 5.0 12.7 11 4.8 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Peptidase_S64 PF08192.11 CDJ44071.1 - 8.8 4.7 15.1 0.053 12.0 2.8 2.3 1 1 0 2 2 2 0 Peptidase family S64 RRM_1 PF00076.22 CDJ44072.1 - 4.1e-12 45.7 0.1 2.7e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ44072.1 - 0.00016 21.5 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Phage_TAC_1 PF06222.11 CDJ44072.1 - 0.0011 18.7 0.3 0.014 15.1 0.3 2.1 1 1 0 1 1 1 1 Phage tail assembly chaperone RRM_3 PF08777.11 CDJ44072.1 - 0.086 12.9 0.1 0.34 11.0 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif FtsJ PF01728.19 CDJ44074.1 - 2.8e-51 174.1 0.2 5.7e-51 173.1 0.2 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 CDJ44074.1 - 7.6e-36 123.7 20.9 7.6e-36 123.7 20.9 5.4 6 1 1 7 7 6 1 Spb1 C-terminal domain DUF3381 PF11861.8 CDJ44074.1 - 6.8e-23 81.3 10.3 1.2e-18 67.4 10.9 9.5 6 3 2 9 9 9 4 Domain of unknown function (DUF3381) UpxZ PF06603.11 CDJ44075.1 - 0.0054 17.0 0.1 0.0056 16.9 0.1 1.0 1 0 0 1 1 1 1 UpxZ family of transcription anti-terminator antagonists Autophagy_N PF03986.13 CDJ44076.1 - 3.1e-14 53.1 0.0 3.9e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain SUIM_assoc PF16619.5 CDJ44077.1 - 3 8.0 22.4 0.71 10.0 3.2 3.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Allexi_40kDa PF05549.11 CDJ44079.1 - 4.3 6.8 10.1 3.4 7.1 0.2 2.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein Methyltransf_25 PF13649.6 CDJ44080.1 - 5.1e-13 49.6 0.0 7.1e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ44080.1 - 3.2e-11 43.4 0.0 4.1e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ44080.1 - 3.3e-10 40.5 0.0 5e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ44080.1 - 5.6e-10 39.0 0.0 6.8e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CDJ44080.1 - 2.1e-07 31.6 0.0 3.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ44080.1 - 0.0035 17.2 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF4820 PF16091.5 CDJ44081.1 - 0.03 13.7 3.4 0.03 13.7 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RskA PF10099.9 CDJ44081.1 - 0.031 14.6 7.2 0.032 14.5 7.2 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ44081.1 - 0.18 11.4 17.7 0.17 11.5 17.7 1.0 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ44081.1 - 0.23 10.3 20.1 0.24 10.2 20.1 1.1 1 0 0 1 1 1 0 Androgen receptor LPP20 PF02169.16 CDJ44081.1 - 0.89 9.9 9.8 0.99 9.8 9.8 1.1 1 0 0 1 1 1 0 LPP20 lipoprotein DUF4834 PF16118.5 CDJ44081.1 - 1.5 9.9 5.5 1.5 9.8 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ44081.1 - 1.5 8.7 19.2 1.6 8.7 19.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ44081.1 - 3.7 6.2 6.0 3.9 6.1 6.0 1.0 1 0 0 1 1 1 0 Presenilin UPF0560 PF10577.9 CDJ44081.1 - 4.2 5.7 11.4 4 5.8 11.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3138 PF11336.8 CDJ44081.1 - 6.3 5.3 9.4 6.7 5.2 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2722 PF10846.8 CDJ44081.1 - 6.7 5.5 17.3 6.6 5.6 17.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ44081.1 - 8.7 5.2 31.3 10 5.0 31.3 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FTCD_C PF04961.12 CDJ44082.1 - 0.063 13.0 5.2 0.12 12.1 5.2 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Tweety PF04906.13 CDJ44082.1 - 0.26 9.9 1.1 0.4 9.3 1.1 1.2 1 0 0 1 1 1 0 Tweety SbcCD_C PF13558.6 CDJ44082.1 - 0.31 11.3 1.3 0.68 10.2 1.3 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit EF-hand_7 PF13499.6 CDJ44083.1 - 2.5e-09 37.4 1.1 3.2e-07 30.7 0.5 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ44083.1 - 2.9e-05 23.6 3.0 0.015 15.2 0.3 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_13 PF17958.1 CDJ44083.1 - 0.00044 20.0 0.0 0.00097 18.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CDJ44083.1 - 0.0039 16.6 3.8 0.058 13.0 0.2 3.4 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.6 CDJ44083.1 - 0.13 11.8 0.2 0.13 11.8 0.2 2.0 2 0 0 2 2 2 0 EF hand Terminase_3 PF04466.13 CDJ44083.1 - 0.21 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Phage terminase large subunit V-ATPase_H_C PF11698.8 CDJ44084.1 - 1.7e-38 131.3 1.1 2.2e-38 130.9 1.1 1.1 1 0 0 1 1 1 1 V-ATPase subunit H Cyt-b5 PF00173.28 CDJ44084.1 - 0.035 14.3 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain TFIIA PF03153.13 CDJ44084.1 - 0.79 9.7 6.7 1.1 9.1 6.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SKA1 PF07160.12 CDJ44085.1 - 0.077 12.8 13.1 0.11 12.3 13.1 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF3365 PF11845.8 CDJ44085.1 - 0.35 11.2 7.0 0.44 10.9 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) ABC2_membrane_2 PF12679.7 CDJ44085.1 - 0.77 9.0 2.1 0.74 9.0 2.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein MDM10 PF12519.8 CDJ44085.1 - 1.4 7.7 4.6 1.4 7.7 4.6 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF3584 PF12128.8 CDJ44085.1 - 1.7 6.1 17.8 2.1 5.8 17.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 CDJ44085.1 - 1.9 8.0 13.1 0.16 11.5 8.3 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Mcm10 PF09332.11 CDJ44085.1 - 2.4 7.5 17.0 3.1 7.1 17.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Presenilin PF01080.17 CDJ44085.1 - 3 6.5 10.5 3.4 6.3 10.5 1.1 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 CDJ44085.1 - 3 7.3 17.0 3.4 7.1 17.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist 2OG-FeII_Oxy_2 PF13532.6 CDJ44085.1 - 4.8 7.3 8.6 1.9 8.6 6.3 1.5 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily TERB2 PF15101.6 CDJ44085.1 - 6.2 6.8 15.2 49 3.9 17.0 1.5 2 0 0 2 2 2 0 Telomere-associated protein TERB2 ALMT PF11744.8 CDJ44085.1 - 9.3 5.0 5.9 11 4.7 5.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RR_TM4-6 PF06459.12 CDJ44086.1 - 0.005 16.7 3.2 0.0078 16.1 3.2 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 DUF1640 PF07798.11 CDJ44086.1 - 0.043 13.9 2.3 0.31 11.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF1115 PF06544.12 CDJ44086.1 - 0.087 12.9 1.8 0.13 12.3 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) DUF1840 PF08895.11 CDJ44087.1 - 0.068 13.5 0.3 0.068 13.5 0.3 6.1 5 2 1 6 6 6 0 Domain of unknown function (DUF1840) Pkinase_fungal PF17667.1 CDJ44087.1 - 1.3 7.7 3.8 3.9 6.1 3.5 1.9 2 0 0 2 2 2 0 Fungal protein kinase DUF3801 PF12687.7 CDJ44087.1 - 3.3 7.7 21.9 0.22 11.6 8.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3801) DUF4366 PF14283.6 CDJ44087.1 - 9.8 6.2 19.3 35 4.4 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) RRM_1 PF00076.22 CDJ44088.1 - 1.1e-15 57.1 0.2 2.9e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ44088.1 - 0.00044 19.9 0.0 0.00049 19.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gate PF07670.14 CDJ44089.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.5 1 1 0 1 1 1 0 Nucleoside recognition CbtA PF09490.10 CDJ44089.1 - 0.059 13.1 25.4 0.11 12.3 0.2 2.2 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) LMBR1 PF04791.16 CDJ44091.1 - 1.6 7.5 8.6 1.8 7.3 8.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Spt20 PF12090.8 CDJ44093.1 - 0.056 13.1 5.2 0.066 12.8 5.2 1.1 1 0 0 1 1 1 0 Spt20 family DUF1180 PF06679.12 CDJ44093.1 - 1.7 9.0 6.4 2.2 8.7 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TAFII28 PF04719.14 CDJ44094.1 - 0.011 15.9 0.1 0.026 14.6 0.1 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Herpes_pp85 PF04637.12 CDJ44094.1 - 6.7 5.0 5.9 11 4.3 5.9 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) LMBR1 PF04791.16 CDJ44096.1 - 0.068 12.1 1.9 0.5 9.2 4.1 1.4 2 0 0 2 2 2 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 CDJ44096.1 - 4.6 6.7 22.3 8.1 5.9 22.3 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ribosomal_S2 PF00318.20 CDJ44096.1 - 7.2 5.8 0.0 7.2 5.8 0.0 2.8 3 1 0 3 3 3 0 Ribosomal protein S2 NicO PF03824.16 CDJ44097.1 - 0.071 12.4 0.6 0.39 10.0 1.3 1.7 2 0 0 2 2 2 0 High-affinity nickel-transport protein YAcAr PF10686.9 CDJ44099.1 - 0.00033 20.5 13.7 0.097 12.6 0.4 4.2 4 0 0 4 4 4 3 YspA, cpYpsA-related SLOG family Vault PF01505.18 CDJ44099.1 - 0.01 16.0 0.7 9.3 6.5 0.1 3.3 3 0 0 3 3 3 0 Major Vault Protein repeat domain DUF1761 PF08570.10 CDJ44099.1 - 0.037 14.3 2.8 14 6.0 0.6 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF1761) Phage_TAC_11 PF11836.8 CDJ44099.1 - 0.099 12.8 11.3 2.2 8.5 0.3 3.3 3 0 0 3 3 3 0 Phage tail tube protein, GTA-gp10 XRN_N PF03159.18 CDJ44099.1 - 0.33 10.3 0.3 77 2.6 0.0 2.9 3 0 0 3 3 3 0 XRN 5'-3' exonuclease N-terminus HEAT_EZ PF13513.6 CDJ44100.1 - 2.6e-13 50.2 22.3 7.9e-09 35.8 0.0 15.4 13 3 3 16 16 16 6 HEAT-like repeat HEAT PF02985.22 CDJ44100.1 - 6.2e-11 41.6 33.9 0.024 14.9 0.7 12.0 12 0 0 12 12 12 4 HEAT repeat Cnd1 PF12717.7 CDJ44100.1 - 8.8e-07 29.1 2.9 0.19 11.8 0.2 3.6 3 0 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CDJ44100.1 - 8.3e-05 23.1 0.1 0.29 11.7 0.0 4.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 CDJ44100.1 - 0.00015 21.6 27.9 0.46 10.6 0.8 8.4 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat TAFH PF07531.14 CDJ44100.1 - 0.002 18.2 1.1 0.002 18.2 1.1 5.4 5 1 0 5 5 5 1 NHR1 homology to TAF SMYLE_N PF18615.1 CDJ44100.1 - 0.12 11.9 5.9 0.62 9.6 0.1 2.4 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SARAF PF06682.12 CDJ44100.1 - 1.7 8.2 6.6 0.28 10.8 1.1 2.3 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis CCDC53 PF10152.9 CDJ44100.1 - 6.2 7.2 18.0 6.6 7.1 1.6 3.7 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex SpoIIE PF07228.12 CDJ44101.1 - 3.8e-05 23.7 1.2 4.7e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PDEase_I PF00233.19 CDJ44102.1 - 2.4e-31 109.3 0.1 4e-31 108.6 0.1 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF2722 PF10846.8 CDJ44104.1 - 0.029 13.3 1.4 0.033 13.2 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pex26 PF07163.12 CDJ44104.1 - 0.18 11.1 6.4 1.7 7.8 3.3 2.0 1 1 0 2 2 2 0 Pex26 protein OmpH PF03938.14 CDJ44104.1 - 0.33 11.3 13.9 2.5 8.4 7.2 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Vir_act_alpha_C PF10400.9 CDJ44104.1 - 1.6 9.5 6.9 0.94 10.2 1.3 2.3 2 1 0 2 2 2 0 Virulence activator alpha C-term DUF4456 PF14644.6 CDJ44104.1 - 2.3 7.8 14.9 7.7 6.1 9.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) Activator_LAG-3 PF11498.8 CDJ44104.1 - 3.4 6.5 20.3 0.35 9.8 14.2 1.9 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Crust_neurohorm PF01147.17 CDJ44106.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family PCMT PF01135.19 CDJ44108.1 - 5.1e-22 78.7 0.0 7e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Isy1 PF06246.12 CDJ44109.1 - 6.2e-06 26.0 5.3 9.3e-06 25.4 5.3 1.2 1 0 0 1 1 1 1 Isy1-like splicing family SR-25 PF10500.9 CDJ44109.1 - 0.00013 21.6 8.3 0.00018 21.2 8.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.13 CDJ44109.1 - 0.051 12.6 8.8 0.059 12.4 8.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Glyco_hydro_9 PF00759.19 CDJ44109.1 - 0.67 9.3 8.6 1.4 8.2 8.6 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 9 Dehydrin PF00257.19 CDJ44109.1 - 0.74 10.4 11.7 0.035 14.7 6.2 1.6 2 0 0 2 2 2 0 Dehydrin EphA2_TM PF14575.6 CDJ44109.1 - 1.5 9.7 3.9 0.76 10.7 0.8 2.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pep_M12B_propep PF01562.19 CDJ44109.1 - 2.4 8.4 6.5 1.1 9.5 1.1 2.0 1 1 0 2 2 2 0 Reprolysin family propeptide DUF572 PF04502.13 CDJ44109.1 - 3.7 7.1 9.3 4.5 6.8 9.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_60s PF00428.19 CDJ44109.1 - 4.6 7.9 18.8 15 6.2 16.2 2.2 1 1 1 2 2 2 0 60s Acidic ribosomal protein MDFI PF15316.6 CDJ44109.1 - 8.9 6.4 8.6 2.5 8.1 5.8 1.5 1 1 0 1 1 1 0 MyoD family inhibitor Synaptobrevin PF00957.21 CDJ44110.1 - 4.7e-17 61.6 0.3 7.8e-17 60.9 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin NAM-associated PF14303.6 CDJ44111.1 - 9.8e-05 23.1 0.1 9.8e-05 23.1 0.1 5.9 3 3 2 5 5 5 1 No apical meristem-associated C-terminal domain LMBR1 PF04791.16 CDJ44111.1 - 3.2 6.5 11.8 0.58 9.0 7.5 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein Shadoo PF14999.6 CDJ44112.1 - 0.12 12.5 11.0 0.22 11.6 11.0 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective COQ7 PF03232.13 CDJ44112.1 - 0.18 11.6 5.2 0.39 10.5 1.5 2.1 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 CPSF_A PF03178.15 CDJ44114.1 - 8.1e-21 74.7 0.0 1.5e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 CDJ44114.1 - 2.6e-06 26.3 0.0 4.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GREB1 PF15782.5 CDJ44114.1 - 7.7 3.5 6.9 14 2.6 6.9 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer E1-E2_ATPase PF00122.20 CDJ44115.1 - 1.7e-20 73.3 0.1 1.2e-19 70.6 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ44115.1 - 1.1e-11 45.5 2.8 1.2e-05 25.7 0.1 4.1 4 0 0 4 4 4 3 haloacid dehalogenase-like hydrolase SUIM_assoc PF16619.5 CDJ44115.1 - 0.00013 21.9 0.0 0.00013 21.9 0.0 11.3 5 4 5 11 11 11 1 Unstructured region C-term to UIM in Ataxin3 Cation_ATPase_C PF00689.21 CDJ44115.1 - 0.034 13.9 7.3 0.02 14.6 1.0 2.5 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Ribonuc_red_lgC PF02867.15 CDJ44116.1 - 2.7e-182 607.0 0.0 3.4e-182 606.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CDJ44116.1 - 8.2e-24 83.4 0.1 1.7e-23 82.4 0.1 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CDJ44116.1 - 6.5e-11 42.7 0.0 1.4e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain CDK2AP PF09806.9 CDJ44120.1 - 0.082 13.0 9.6 0.11 12.5 9.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4614 PF15391.6 CDJ44120.1 - 0.1 12.6 10.7 0.13 12.3 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Sporozoite_P67 PF05642.11 CDJ44120.1 - 0.54 8.3 11.6 0.6 8.1 11.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.9 CDJ44120.1 - 0.87 8.1 10.8 0.91 8.0 10.8 1.0 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ44120.1 - 1.2 7.9 9.5 1.3 7.8 9.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF515 PF04415.12 CDJ44120.1 - 2.9 6.2 16.2 3 6.1 16.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Miga PF10265.9 CDJ44120.1 - 3 6.7 8.6 3.2 6.6 8.6 1.0 1 0 0 1 1 1 0 Mitoguardin AF-4 PF05110.13 CDJ44120.1 - 5.8 4.9 18.7 7.5 4.5 18.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CCDC106 PF15794.5 CDJ44120.1 - 6.6 6.4 8.9 8.5 6.0 8.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Spt20 PF12090.8 CDJ44121.1 - 0.85 9.2 33.9 0.55 9.8 4.5 2.2 2 0 0 2 2 2 0 Spt20 family RR_TM4-6 PF06459.12 CDJ44121.1 - 3.3 7.5 8.6 3.2 7.5 4.5 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 CDJ44121.1 - 3.6 6.9 6.6 8.1 5.8 6.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2722 PF10846.8 CDJ44121.1 - 4.1 6.2 27.8 0.72 8.7 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) PEX11 PF05648.14 CDJ44121.1 - 4.3 6.7 6.1 16 4.9 1.0 2.3 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) SR-25 PF10500.9 CDJ44122.1 - 0.012 15.3 9.3 0.013 15.2 9.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCP_MauG PF03150.14 CDJ44123.1 - 0.03 15.0 1.4 0.03 15.0 1.4 2.7 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase FACT-Spt16_Nlob PF14826.6 CDJ44123.1 - 6.7 6.5 7.6 20 4.9 0.4 3.2 3 2 0 3 3 3 0 FACT complex subunit SPT16 N-terminal lobe domain OATP PF03137.20 CDJ44125.1 - 0.27 9.5 1.8 0.34 9.1 1.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TIP49 PF06068.13 CDJ44131.1 - 4e-64 217.1 0.2 4.8e-64 216.8 0.2 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain AAA PF00004.29 CDJ44131.1 - 1.1e-08 35.5 0.0 1.4e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ44131.1 - 1.3e-06 28.9 0.1 1.7e-06 28.5 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 CDJ44131.1 - 1.1e-05 24.9 0.1 1.3e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain RuvB_N PF05496.12 CDJ44131.1 - 1.2e-05 25.1 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 CDJ44131.1 - 3.8e-05 23.1 0.1 6.8e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 CDJ44131.1 - 0.0001 22.7 0.1 0.00014 22.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDJ44131.1 - 0.00045 19.7 0.2 0.00064 19.2 0.2 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CDJ44131.1 - 0.00059 19.5 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CDJ44131.1 - 0.0008 19.4 0.0 0.0013 18.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 CDJ44131.1 - 0.0027 17.1 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.6 CDJ44131.1 - 0.0028 17.8 0.0 0.0041 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CDJ44131.1 - 0.0042 16.4 0.0 0.0049 16.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CDJ44131.1 - 0.005 16.8 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 CDJ44131.1 - 0.0053 17.3 0.0 0.0078 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CDJ44131.1 - 0.0088 15.6 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 CDJ44131.1 - 0.017 15.1 0.2 0.036 14.1 0.2 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 CDJ44131.1 - 0.02 14.7 0.1 0.031 14.0 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 CDJ44131.1 - 0.02 15.1 0.1 0.028 14.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 CDJ44131.1 - 0.023 14.6 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase CPT PF07931.12 CDJ44131.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.17 CDJ44131.1 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 CDJ44131.1 - 0.029 14.1 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 CDJ44131.1 - 0.029 13.8 0.7 0.083 12.3 0.1 2.0 3 0 0 3 3 3 0 PhoH-like protein ABC_tran PF00005.27 CDJ44131.1 - 0.031 14.8 0.0 0.04 14.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 CDJ44131.1 - 0.05 13.9 0.7 0.068 13.5 0.7 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDJ44131.1 - 0.15 12.5 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase RskA PF10099.9 CDJ44134.1 - 0.0052 17.1 12.3 0.028 14.7 9.6 2.1 1 1 1 2 2 2 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ44134.1 - 0.069 12.1 21.7 0.19 10.6 10.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) CCDC53 PF10152.9 CDJ44134.1 - 0.38 11.2 9.8 0.36 11.2 4.4 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Peptidase_S49_N PF08496.10 CDJ44134.1 - 0.39 10.8 8.0 1 9.4 4.9 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SpoIIP PF07454.11 CDJ44134.1 - 0.54 9.7 7.2 0.38 10.2 2.4 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF3371 PF11851.8 CDJ44134.1 - 0.73 10.9 14.4 4.4 8.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Mak16 PF04874.14 CDJ44134.1 - 0.98 10.1 8.6 3.2 8.4 3.7 2.2 2 0 0 2 2 2 0 Mak16 protein C-terminal region WRNPLPNID PF15017.6 CDJ44134.1 - 1 10.3 16.6 0.38 11.7 0.7 2.3 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box DUF4834 PF16118.5 CDJ44134.1 - 2 9.4 9.6 24 6.0 6.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) EMC3_TMCO1 PF01956.16 CDJ44134.1 - 2.6 7.8 8.5 0.14 11.9 1.3 2.0 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like WASH-7_C PF14746.6 CDJ44134.1 - 4.2 7.0 13.6 17 5.0 9.9 2.2 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Spt20 PF12090.8 CDJ44134.1 - 5.4 6.5 39.6 0.49 10.0 4.5 2.2 2 0 0 2 2 2 0 Spt20 family CLN3 PF02487.17 CDJ44134.1 - 5.7 5.9 8.2 24 3.8 5.0 2.0 2 0 0 2 2 2 0 CLN3 protein baeRF_family10 PF18854.1 CDJ44134.1 - 6.7 7.0 12.8 0.26 11.5 5.9 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 DUF2126 PF09899.9 CDJ44134.1 - 7.5 4.5 12.5 0.59 8.1 6.9 1.7 1 1 1 2 2 2 0 Putative amidoligase enzyme (DUF2126) DUF2072 PF09845.9 CDJ44134.1 - 8.6 6.6 9.5 36 4.6 0.1 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein Endonuc_Holl PF10107.9 CDJ44134.1 - 9.2 6.1 9.9 6.3 6.6 5.5 2.0 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Efg1 PF10153.9 CDJ44134.1 - 9.5 6.6 14.9 2.7 8.4 7.2 2.1 2 0 0 2 2 2 0 rRNA-processing protein Efg1 Guanylate_cyc_2 PF09778.9 CDJ44137.1 - 1.6e-08 34.2 0.0 1.7e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Guanylylate cyclase DUF3335 PF11814.8 CDJ44137.1 - 0.016 14.7 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase_C39 like family SR-25 PF10500.9 CDJ44138.1 - 0.015 14.9 7.6 0.022 14.4 7.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PMD PF10536.9 CDJ44138.1 - 0.037 13.1 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 Plant mobile domain SMC_Nse1 PF07574.13 CDJ44138.1 - 0.055 13.4 0.0 0.068 13.1 0.0 1.1 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex AF-4 PF05110.13 CDJ44138.1 - 0.062 11.4 6.0 0.055 11.6 6.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Secretin_N PF03958.17 CDJ44138.1 - 0.065 13.6 0.6 0.089 13.2 0.6 1.3 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain IMUP PF15761.5 CDJ44138.1 - 0.12 13.1 7.7 0.28 11.9 7.7 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein ODV-E18 PF10717.9 CDJ44138.1 - 0.18 11.7 2.0 0.37 10.7 2.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF755 PF05501.11 CDJ44138.1 - 3.4 7.9 11.9 5.3 7.3 11.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AP2 PF00847.20 CDJ44139.1 - 4.1e-10 39.7 1.2 4.1e-10 39.7 1.2 3.9 4 0 0 4 4 4 1 AP2 domain SR-25 PF10500.9 CDJ44139.1 - 0.00026 20.7 8.9 0.00026 20.7 8.9 5.9 6 1 0 6 6 6 2 Nuclear RNA-splicing-associated protein PAT1 PF09770.9 CDJ44139.1 - 0.076 11.3 76.2 0.12 10.7 51.1 2.7 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 zf-C4H2 PF10146.9 CDJ44139.1 - 1 9.7 45.1 0.71 10.1 32.8 3.1 2 0 0 2 2 2 0 Zinc finger-containing protein Caldesmon PF02029.15 CDJ44139.1 - 3.4 6.3 61.2 0.63 8.7 42.9 2.5 2 0 0 2 2 2 0 Caldesmon Exonuc_VII_L PF02601.15 CDJ44139.1 - 3.6 7.1 79.0 2.1 7.9 41.1 3.7 2 1 1 3 3 3 0 Exonuclease VII, large subunit DUF802 PF05650.11 CDJ44140.1 - 0.00077 19.9 1.5 0.002 18.5 1.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF802) Ras PF00071.22 CDJ44142.1 - 1.4e-41 141.8 0.0 1.6e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ44142.1 - 1.5e-32 112.3 0.0 1.7e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ44142.1 - 1.2e-09 37.9 0.0 1.3e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ44142.1 - 2.3e-06 27.7 0.0 2.6e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 CDJ44142.1 - 0.0011 18.7 0.1 0.0015 18.3 0.1 1.4 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 CDJ44142.1 - 0.0039 16.6 0.0 0.0047 16.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDJ44142.1 - 0.013 15.4 0.1 0.025 14.5 0.1 1.6 1 1 0 1 1 1 0 RsgA GTPase GTP_EFTU PF00009.27 CDJ44142.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CDJ44142.1 - 0.028 14.7 0.0 0.038 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ44142.1 - 0.034 14.5 0.1 0.05 14.0 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 CDJ44142.1 - 0.065 12.7 0.0 0.078 12.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 CDJ44142.1 - 0.071 13.6 0.0 0.12 12.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 CDJ44142.1 - 0.097 12.1 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 CDJ44142.1 - 0.1 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 CDJ44142.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_14 PF13173.6 CDJ44142.1 - 0.13 12.3 0.1 0.31 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDJ44142.1 - 0.14 12.5 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 CDJ44142.1 - 0.16 12.5 0.0 0.37 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF3509 PF12021.8 CDJ44143.1 - 0.0036 17.0 2.4 0.0056 16.4 1.6 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3509) CENP-K PF11802.8 CDJ44143.1 - 0.025 14.2 6.5 0.029 14.0 6.5 1.1 1 0 0 1 1 1 0 Centromere-associated protein K Apolipoprotein PF01442.18 CDJ44143.1 - 0.041 13.8 12.1 0.068 13.0 12.1 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CNDH2_M PF16869.5 CDJ44143.1 - 0.1 13.3 0.5 0.17 12.6 0.5 1.5 1 1 0 1 1 1 0 PF16858 DUF3584 PF12128.8 CDJ44143.1 - 0.39 8.2 12.8 1.5 6.2 13.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) FHIPEP PF00771.20 CDJ44144.1 - 0.11 10.9 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family BTB_2 PF02214.22 CDJ44146.1 - 2.7e-13 50.0 0.0 4.4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CYSTM PF12734.7 CDJ44146.1 - 1.5 9.2 22.5 0.48 10.8 18.5 2.3 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance DUF4470 PF14737.6 CDJ44147.1 - 0.00022 21.3 3.3 0.011 15.8 3.3 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) HCO3_cotransp PF00955.21 CDJ44147.1 - 4.8 5.9 5.3 6.5 5.5 5.3 1.3 1 0 0 1 1 1 0 HCO3- transporter family CRT10 PF08728.10 CDJ44147.1 - 5.5 5.0 11.0 5.7 5.0 11.0 1.1 1 0 0 1 1 1 0 CRT10 O-antigen_lig PF13425.6 CDJ44147.1 - 6.9 5.3 9.4 10 4.8 9.4 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SID-1_RNA_chan PF13965.6 CDJ44147.1 - 9.9 4.4 10.5 1.5 7.2 6.9 1.4 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 TFIIA PF03153.13 CDJ44148.1 - 1.9 8.4 21.2 2.2 8.2 21.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MscS_TM PF12794.7 CDJ44148.1 - 9.1 5.0 6.6 1.5 7.6 2.7 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF2722 PF10846.8 CDJ44150.1 - 0.00039 19.5 1.3 0.00046 19.3 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ44150.1 - 0.2 11.6 3.0 0.32 10.9 3.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RskA PF10099.9 CDJ44155.1 - 0.00045 20.6 13.7 0.0007 19.9 13.7 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA K_channel_TID PF07941.11 CDJ44155.1 - 0.0011 19.3 7.8 0.0011 19.3 7.8 2.0 2 0 0 2 2 2 1 Potassium channel Kv1.4 tandem inactivation domain Trp_oprn_chp PF09534.10 CDJ44155.1 - 0.0025 17.7 3.4 0.0032 17.3 3.4 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3995 PF13160.6 CDJ44155.1 - 0.018 15.4 1.0 0.025 14.9 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) TFIIA PF03153.13 CDJ44155.1 - 0.029 14.4 10.7 0.03 14.3 10.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LapA_dom PF06305.11 CDJ44155.1 - 0.086 12.7 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PepSY_2 PF13670.6 CDJ44155.1 - 0.49 10.4 10.7 0.79 9.8 9.7 1.8 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain RRM_3 PF08777.11 CDJ44156.1 - 0.27 11.3 0.0 0.27 11.3 0.0 2.4 3 0 0 3 3 3 0 RNA binding motif Mre11_DNA_bind PF04152.14 CDJ44156.1 - 1.6 9.0 11.9 0.32 11.3 6.5 2.3 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain DHHC PF01529.20 CDJ44157.1 - 0.00012 22.1 2.2 0.00012 22.1 2.2 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase AI-2E_transport PF01594.16 CDJ44157.1 - 0.0027 16.9 1.3 0.033 13.3 0.3 2.6 2 0 0 2 2 2 1 AI-2E family transporter Baculo_PEP_C PF04513.12 CDJ44157.1 - 0.015 15.4 13.0 0.032 14.3 13.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Focal_AT PF03623.13 CDJ44157.1 - 0.088 12.8 5.0 0.17 11.9 5.0 1.4 1 0 0 1 1 1 0 Focal adhesion targeting region NAP PF00956.18 CDJ44157.1 - 0.16 11.1 1.1 0.35 10.0 1.1 1.5 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) V-ATPase_C PF03223.15 CDJ44157.1 - 0.17 11.3 3.9 0.19 11.1 2.7 1.6 2 0 0 2 2 2 0 V-ATPase subunit C YojJ PF10372.9 CDJ44157.1 - 0.23 11.6 10.8 0.47 10.6 10.8 1.5 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus IMD PF08397.11 CDJ44157.1 - 0.35 10.2 10.2 0.83 9.0 10.2 1.6 1 0 0 1 1 1 0 IRSp53/MIM homology domain DUF1664 PF07889.12 CDJ44157.1 - 0.41 10.7 8.1 2.2 8.3 6.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) 5_nucleotid PF05761.14 CDJ44157.1 - 0.88 8.4 2.7 1.6 7.5 2.7 1.3 1 0 0 1 1 1 0 5' nucleotidase family V_ATPase_I PF01496.19 CDJ44157.1 - 1.4 6.7 4.8 0.62 7.9 1.1 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.9 CDJ44157.1 - 1.5 9.2 9.8 4.8 7.6 9.8 1.9 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YkuI_C PF10388.9 CDJ44157.1 - 2.1 8.1 3.5 3.5 7.4 3.5 1.2 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain FapA PF03961.13 CDJ44157.1 - 2.6 6.5 6.8 4 5.9 6.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Utp12 PF04003.12 CDJ44157.1 - 2.7 8.3 15.2 5.5 7.4 15.2 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family YlqD PF11068.8 CDJ44157.1 - 4 7.8 27.4 10 6.5 27.4 1.6 1 0 0 1 1 1 0 YlqD protein UPF0242 PF06785.11 CDJ44157.1 - 7.1 6.7 21.4 19 5.3 18.8 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus F_actin_cap_B PF01115.17 CDJ44159.1 - 5.2e-37 127.8 0.0 1.8e-36 126.0 0.0 1.6 1 1 1 2 2 2 1 F-actin capping protein, beta subunit DUF2722 PF10846.8 CDJ44159.1 - 3.6e-05 22.9 5.0 3.6e-05 22.9 5.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ44159.1 - 0.0027 17.8 36.8 0.0027 17.8 36.8 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit TT_ORF1 PF02956.14 CDJ44159.1 - 0.071 11.8 7.3 0.097 11.3 7.3 1.1 1 0 0 1 1 1 0 TT viral orf 1 RNA_pol_Rpb1_5 PF04998.17 CDJ44159.1 - 0.1 12.0 0.2 0.12 11.8 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF4834 PF16118.5 CDJ44159.1 - 7.9 7.5 7.1 19 6.3 7.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) HALZ PF02183.18 CDJ44160.1 - 0.005 17.0 0.2 0.005 17.0 0.2 2.6 3 0 0 3 3 3 1 Homeobox associated leucine zipper DUF489 PF04356.12 CDJ44160.1 - 0.06 13.3 4.4 0.074 13.0 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Mt_ATP-synt_B PF05405.14 CDJ44160.1 - 0.077 12.6 11.6 0.11 12.2 11.6 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TMPIT PF07851.13 CDJ44160.1 - 1.1 8.5 5.9 1.2 8.3 5.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 CDJ44160.1 - 1.1 8.5 13.7 1.1 8.5 12.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) RskA PF10099.9 CDJ44161.1 - 0.073 13.4 3.3 0.085 13.1 3.3 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA zf-LITAF-like PF10601.9 CDJ44163.1 - 1.3e-13 51.0 6.4 1.3e-13 51.0 6.4 2.2 1 1 1 2 2 2 1 LITAF-like zinc ribbon domain zinc_ribbon_15 PF17032.5 CDJ44163.1 - 0.00091 19.9 3.1 0.095 13.5 0.4 2.7 2 0 0 2 2 2 2 zinc-ribbon family RecR PF02132.15 CDJ44163.1 - 3.2 7.4 6.0 0.68 9.6 1.8 1.9 2 0 0 2 2 2 0 RecR protein Elf1 PF05129.13 CDJ44163.1 - 5.5 7.1 6.2 10 6.2 1.7 2.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like XPG_I PF00867.18 CDJ44164.1 - 1.9e-28 98.6 0.0 4.1e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDJ44164.1 - 9.7e-27 93.4 0.0 3.2e-26 91.7 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 CDJ44164.1 - 9.5e-05 22.9 0.0 0.00029 21.4 0.0 1.8 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_lambd_f PF10391.9 CDJ44164.1 - 0.045 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda IQ PF00612.27 CDJ44166.1 - 0.054 13.3 2.9 0.054 13.3 2.9 5.1 4 0 0 4 4 4 0 IQ calmodulin-binding motif ABC_tran_2 PF16949.5 CDJ44166.1 - 1 8.1 5.5 1.4 7.7 5.5 1.1 1 0 0 1 1 1 0 Putative ATP-binding cassette XK-related PF09815.9 CDJ44166.1 - 3.5 6.6 10.3 4.2 6.3 10.3 1.2 1 0 0 1 1 1 0 XK-related protein PARG_cat PF05028.14 CDJ44168.1 - 2.2e-78 263.9 0.0 4.1e-78 263.0 0.0 1.3 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Cucumopine_C PF18631.1 CDJ44168.1 - 0.016 15.1 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Cucumopine synthase C-terminal helical bundle domain AKAP_110 PF05716.13 CDJ44168.1 - 0.03 12.6 0.0 0.044 12.0 0.0 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) SUIM_assoc PF16619.5 CDJ44168.1 - 1.1 9.3 5.9 0.36 10.9 0.7 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SUIM_assoc PF16619.5 CDJ44169.1 - 0.023 14.8 0.6 0.023 14.8 0.6 5.3 3 1 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF87 PF01935.17 CDJ44169.1 - 0.5 10.4 1.7 1.4 9.0 1.7 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain RRN3 PF05327.11 CDJ44171.1 - 0.0089 14.6 0.4 0.011 14.3 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 REC1 PF18501.1 CDJ44171.1 - 0.012 15.5 2.4 0.014 15.3 2.4 1.1 1 0 0 1 1 1 0 Alpha helical recognition lobe domain ECM11 PF15463.6 CDJ44171.1 - 0.019 15.6 1.4 0.046 14.3 1.4 1.7 1 1 0 1 1 1 0 Extracellular mutant protein 11 Efg1 PF10153.9 CDJ44171.1 - 0.033 14.6 2.9 0.055 13.8 2.9 1.4 1 0 0 1 1 1 0 rRNA-processing protein Efg1 RskA PF10099.9 CDJ44171.1 - 0.47 10.7 8.1 1.8 8.8 5.3 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF883 PF05957.13 CDJ44171.1 - 0.79 10.4 6.6 0.92 10.2 0.7 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF3138 PF11336.8 CDJ44171.1 - 1.2 7.7 4.0 1.4 7.5 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ATP_bind_1 PF03029.17 CDJ44172.1 - 2.1e-53 181.6 0.0 2.3e-25 89.8 0.0 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 CDJ44172.1 - 3.8e-06 26.8 1.6 3.8e-06 26.8 1.6 3.0 3 1 0 4 4 3 1 AAA domain AAA_29 PF13555.6 CDJ44172.1 - 1.5e-05 24.7 0.1 4e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CDJ44172.1 - 2.8e-05 24.5 0.1 2.8e-05 24.5 0.1 3.1 3 1 0 3 3 3 1 AAA ATPase domain MeaB PF03308.16 CDJ44172.1 - 5.4e-05 22.3 0.3 0.0014 17.7 0.2 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 CDJ44172.1 - 0.00054 19.6 0.1 0.49 10.0 0.3 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CDJ44172.1 - 0.0035 16.7 0.1 0.0062 15.8 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin NTPase_1 PF03266.15 CDJ44172.1 - 0.0038 17.2 0.3 0.015 15.2 0.9 1.6 2 0 0 2 2 1 1 NTPase CbiA PF01656.23 CDJ44172.1 - 0.0039 17.2 0.0 0.011 15.8 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 CDJ44172.1 - 0.0044 16.3 0.2 0.0072 15.5 0.2 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 CDJ44172.1 - 0.0047 17.5 0.0 0.0099 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 CDJ44172.1 - 0.0086 16.0 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ATPase_2 PF01637.18 CDJ44172.1 - 0.009 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 CDJ44172.1 - 0.0092 16.5 1.4 0.063 13.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.6 CDJ44172.1 - 0.012 15.6 0.0 0.1 12.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ44172.1 - 0.013 15.4 0.1 7.2 6.5 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase cobW PF02492.19 CDJ44172.1 - 0.014 15.0 2.7 0.081 12.5 1.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CDJ44172.1 - 0.015 15.4 1.2 0.034 14.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CDJ44172.1 - 0.019 15.3 0.1 0.044 14.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CDJ44172.1 - 0.02 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.14 CDJ44172.1 - 0.021 14.0 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase TsaE PF02367.17 CDJ44172.1 - 0.04 13.9 0.2 0.068 13.2 0.2 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CDJ44172.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 CDJ44172.1 - 0.055 12.9 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 CDJ44172.1 - 0.059 13.5 0.0 10 6.2 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 CDJ44172.1 - 0.066 13.1 0.7 0.066 13.1 0.7 1.8 2 0 0 2 2 2 0 NACHT domain Viral_helicase1 PF01443.18 CDJ44172.1 - 0.068 12.9 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase G-alpha PF00503.20 CDJ44172.1 - 0.078 12.1 0.1 0.53 9.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit PRK PF00485.18 CDJ44172.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 CDJ44172.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.14 CDJ44172.1 - 0.14 10.0 0.1 0.21 9.5 0.1 1.1 1 0 0 1 1 1 0 Helicase AAA_14 PF13173.6 CDJ44172.1 - 0.17 11.9 0.6 0.58 10.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain SRPRB PF09439.10 CDJ44172.1 - 0.23 10.9 0.5 23 4.3 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NFACT-C PF11923.8 CDJ44173.1 - 1.8e-17 63.2 0.0 1.8e-17 63.2 0.0 3.0 3 1 0 3 3 3 1 NFACT protein C-terminal domain RskA PF10099.9 CDJ44173.1 - 0.012 16.0 6.2 0.012 16.0 6.2 3.9 1 1 2 3 3 3 0 Anti-sigma-K factor rskA ARA70 PF12489.8 CDJ44175.1 - 0.04 14.1 2.4 0.052 13.7 2.4 1.2 1 0 0 1 1 1 0 Nuclear coactivator Androgen_recep PF02166.16 CDJ44175.1 - 0.11 11.3 1.8 0.12 11.2 1.8 1.2 1 0 0 1 1 1 0 Androgen receptor SR-25 PF10500.9 CDJ44176.1 - 0.0025 17.4 21.0 0.0025 17.4 21.0 4.5 3 2 1 4 4 4 2 Nuclear RNA-splicing-associated protein RSRP PF17069.5 CDJ44176.1 - 0.0081 15.8 20.4 0.0081 15.8 20.4 4.0 4 0 0 4 4 4 1 Arginine/Serine-Rich protein 1 EspG PF06872.11 CDJ44178.1 - 0.11 11.0 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 EspG protein DUF4596 PF15363.6 CDJ44180.1 - 0.043 14.1 0.1 0.23 11.7 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) PIN_8 PF18476.1 CDJ44181.1 - 3.9 7.3 7.3 8.1 6.2 7.3 1.6 1 0 0 1 1 1 0 PIN like domain PT PF04886.12 CDJ44182.1 - 0.028 14.0 12.4 0.028 14.0 12.4 2.4 2 1 0 2 2 2 0 PT repeat SHR3_chaperone PF08229.11 CDJ44184.1 - 0.16 10.9 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 Arm_3 PF16186.5 CDJ44185.1 - 5.5e-14 51.5 0.0 1.4e-13 50.2 0.0 1.6 2 0 0 2 2 2 1 Atypical Arm repeat Mlh1_C PF16413.5 CDJ44186.1 - 5.4e-16 58.8 3.7 3.8e-15 56.0 3.7 1.9 1 1 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus CLN3 PF02487.17 CDJ44186.1 - 0.031 13.3 0.1 0.035 13.1 0.1 1.0 1 0 0 1 1 1 0 CLN3 protein DUF4667 PF15700.5 CDJ44187.1 - 0.045 13.9 0.2 0.047 13.8 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) FAM199X PF15814.5 CDJ44188.1 - 0.36 9.8 8.3 0.38 9.8 8.3 1.1 1 0 0 1 1 1 0 Protein family FAM199X SR-25 PF10500.9 CDJ44188.1 - 0.54 9.8 13.8 0.59 9.7 13.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SASRP1 PF15160.6 CDJ44188.1 - 1.4 8.5 6.0 1.7 8.3 6.0 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 DUF4603 PF15376.6 CDJ44188.1 - 4.1 4.7 8.9 4.4 4.6 8.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) ABC_tran PF00005.27 CDJ44189.1 - 1.2e-25 90.6 10.0 3.6e-12 47.0 2.8 3.0 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 CDJ44189.1 - 1.2e-10 41.7 0.0 1.1e-05 25.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ44189.1 - 7.3e-09 35.4 8.2 0.00068 19.1 0.0 3.0 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 CDJ44189.1 - 5.6e-05 22.3 2.1 0.00014 21.0 0.1 2.4 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 CDJ44189.1 - 6.3e-05 22.6 0.0 0.00018 21.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 CDJ44189.1 - 0.00024 20.7 0.0 0.00024 20.7 0.0 2.5 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.6 CDJ44189.1 - 0.00029 21.0 9.4 0.077 13.1 0.0 3.7 3 2 0 3 3 2 2 AAA domain AAA_22 PF13401.6 CDJ44189.1 - 0.0003 21.1 0.0 0.0003 21.1 0.0 3.4 2 1 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 CDJ44189.1 - 0.00045 20.2 4.1 0.00058 19.8 0.5 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 CDJ44189.1 - 0.00048 20.7 0.1 0.00048 20.7 0.1 4.2 1 1 2 3 3 1 1 AAA domain MMR_HSR1 PF01926.23 CDJ44189.1 - 0.00048 20.2 0.0 0.0034 17.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 CDJ44189.1 - 0.0015 18.2 0.1 0.16 11.6 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran_Xtn PF12848.7 CDJ44189.1 - 0.0015 18.5 0.9 0.0015 18.5 0.9 5.0 4 1 0 4 4 3 1 ABC transporter AAA_28 PF13521.6 CDJ44189.1 - 0.0016 18.7 0.1 0.0016 18.7 0.1 4.1 4 1 0 4 4 2 1 AAA domain NACHT PF05729.12 CDJ44189.1 - 0.0022 17.9 0.0 0.0022 17.9 0.0 3.8 2 1 0 3 3 3 1 NACHT domain G-alpha PF00503.20 CDJ44189.1 - 0.0025 17.1 0.4 0.0025 17.1 0.4 2.3 3 0 0 3 3 3 1 G-protein alpha subunit IstB_IS21 PF01695.17 CDJ44189.1 - 0.0031 17.3 0.1 0.033 13.9 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 CDJ44189.1 - 0.0055 17.1 0.7 0.0055 17.1 0.7 3.5 1 1 1 3 3 3 1 AAA ATPase domain AAA_15 PF13175.6 CDJ44189.1 - 0.0055 16.5 0.0 0.0055 16.5 0.0 2.4 4 0 0 4 4 2 1 AAA ATPase domain Septin PF00735.18 CDJ44189.1 - 0.0055 16.0 0.1 0.0055 16.0 0.1 2.5 2 1 1 3 3 3 1 Septin AAA_18 PF13238.6 CDJ44189.1 - 0.0077 16.8 0.7 0.052 14.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 CDJ44189.1 - 0.011 15.5 0.3 0.093 12.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 CDJ44189.1 - 0.011 16.0 3.9 0.027 14.7 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase HAD_SAK_2 PF18143.1 CDJ44189.1 - 0.012 15.9 0.4 0.84 9.9 0.0 3.1 2 1 0 3 3 3 0 HAD domain in Swiss Army Knife RNA repair proteins RNA_helicase PF00910.22 CDJ44189.1 - 0.014 15.8 0.0 0.062 13.7 0.0 2.2 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 CDJ44189.1 - 0.022 14.5 0.2 0.073 12.8 0.2 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 CDJ44189.1 - 0.027 14.2 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 CDJ44189.1 - 0.034 14.6 1.4 0.18 12.2 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 CDJ44189.1 - 0.035 13.1 0.0 0.035 13.1 0.0 2.5 3 1 1 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 CDJ44189.1 - 0.051 13.1 0.2 0.13 11.8 0.0 1.8 2 0 0 2 2 1 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 CDJ44189.1 - 0.083 12.6 0.0 0.083 12.6 0.0 2.8 3 0 0 3 3 3 0 Cytidylate kinase Dynamin_N PF00350.23 CDJ44189.1 - 0.099 12.7 0.0 0.099 12.7 0.0 3.9 3 2 0 3 3 3 0 Dynamin family AAA_14 PF13173.6 CDJ44189.1 - 0.12 12.4 0.0 0.71 9.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 CDJ44189.1 - 0.16 12.2 5.9 0.39 11.0 0.3 3.5 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit Adeno_IVa2 PF02456.15 CDJ44189.1 - 0.18 10.6 0.0 0.18 10.6 0.0 1.6 2 0 0 2 2 1 0 Adenovirus IVa2 protein SRP54 PF00448.22 CDJ44189.1 - 0.18 11.4 0.0 0.18 11.4 0.0 2.9 4 0 0 4 4 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 CDJ44189.1 - 0.22 11.3 1.4 0.64 9.8 0.0 2.5 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein AAA_27 PF13514.6 CDJ44189.1 - 0.36 10.4 0.0 0.36 10.4 0.0 3.5 3 1 1 4 4 4 0 AAA domain AAA_13 PF13166.6 CDJ44189.1 - 0.41 9.2 0.0 0.41 9.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain GTP_EFTU PF00009.27 CDJ44189.1 - 0.63 9.5 6.3 1.1 8.8 0.0 3.2 3 1 1 4 4 3 0 Elongation factor Tu GTP binding domain AAA_5 PF07728.14 CDJ44189.1 - 0.65 10.0 0.0 0.65 10.0 0.0 2.4 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) Peptidase_C97 PF05903.14 CDJ44190.1 - 1.5e-18 67.1 0.0 1.7e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4796 PF16044.5 CDJ44190.1 - 0.076 12.6 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Msg2_C PF12373.8 CDJ44190.1 - 0.097 12.1 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal PA14 PF07691.12 CDJ44191.1 - 1.9e-22 79.7 0.0 3.3e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 PA14 domain LCCL PF03815.19 CDJ44191.1 - 2.9e-09 36.9 0.0 6.9e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 LCCL domain fn2 PF00040.19 CDJ44191.1 - 0.0013 19.0 1.0 0.0027 17.9 1.0 1.6 1 0 0 1 1 1 1 Fibronectin type II domain DNA_pol_D_N PF18018.1 CDJ44192.1 - 2.8e-19 69.5 0.0 5.7e-19 68.5 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Ribosomal_60s PF00428.19 CDJ44192.1 - 0.45 11.1 11.9 0.054 14.1 7.5 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cpn60_TCP1 PF00118.24 CDJ44194.1 - 3e-135 451.6 0.6 1.9e-94 317.0 0.0 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family HemX PF04375.14 CDJ44196.1 - 0.011 15.0 2.5 0.015 14.6 2.5 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase PHD20L1_u1 PF16660.5 CDJ44196.1 - 0.037 14.8 5.9 0.053 14.3 5.7 1.3 1 1 0 1 1 1 0 PHD finger protein 20-like protein 1 DUF1180 PF06679.12 CDJ44196.1 - 0.075 13.4 4.7 0.091 13.2 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) T2SSM PF04612.12 CDJ44196.1 - 0.1 12.7 7.8 0.033 14.2 5.4 1.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Dickkopf_N PF04706.12 CDJ44198.1 - 1.6 9.3 8.2 22 5.6 2.6 3.0 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Pkinase_Tyr PF07714.17 CDJ44199.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase YjbH PF06082.11 CDJ44202.1 - 0.086 11.6 1.2 0.094 11.5 1.2 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH NPBW PF15180.6 CDJ44202.1 - 0.17 11.7 1.1 0.22 11.4 1.1 1.1 1 0 0 1 1 1 0 Neuropeptides B and W FAM184 PF15665.5 CDJ44203.1 - 0.063 13.0 2.5 0.1 12.4 2.4 1.4 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Pkinase PF00069.25 CDJ44204.1 - 3.2e-19 69.3 0.0 3.4e-09 36.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain APH PF01636.23 CDJ44204.1 - 5.8e-06 26.4 3.0 5.8e-06 26.4 3.0 2.9 2 2 1 3 3 3 1 Phosphotransferase enzyme family zf-C3Hc3H PF13891.6 CDJ44205.1 - 0.02 15.2 0.1 0.029 14.7 0.1 1.3 1 0 0 1 1 1 0 Potential DNA-binding domain UPF0240 PF06784.11 CDJ44205.1 - 0.048 13.7 0.1 0.052 13.6 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) Bromodomain PF00439.25 CDJ44206.1 - 6.3e-07 29.4 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF2205 PF10224.9 CDJ44207.1 - 0.00081 19.3 2.2 0.00088 19.2 2.2 1.1 1 0 0 1 1 1 1 Short coiled-coil protein APC_N_CC PF16689.5 CDJ44207.1 - 0.0062 16.6 0.7 0.013 15.6 0.7 1.7 1 0 0 1 1 1 1 Coiled-coil N-terminus of APC, dimerisation domain HalX PF08663.10 CDJ44207.1 - 0.0084 16.4 5.8 0.011 16.1 5.8 1.2 1 0 0 1 1 1 1 HalX domain Macoilin PF09726.9 CDJ44210.1 - 0.21 10.1 27.7 0.26 9.8 27.7 1.0 1 0 0 1 1 1 0 Macoilin family Red1 PF07964.11 CDJ44210.1 - 1.6 6.9 26.7 2 6.5 26.7 1.0 1 0 0 1 1 1 0 Rec10 / Red1 MTBP_C PF14920.6 CDJ44210.1 - 2.3 7.9 24.5 3.6 7.3 24.5 1.3 1 0 0 1 1 1 0 MDM2-binding SRP-alpha_N PF04086.13 CDJ44210.1 - 5.8 6.8 31.2 7.2 6.4 31.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RIFIN PF02009.16 CDJ44210.1 - 6.1 6.6 16.7 8 6.3 16.7 1.1 1 0 0 1 1 1 0 Rifin MAR_sialic_bdg PF10564.9 CDJ44211.1 - 7.9e-30 102.8 7.6 4e-15 55.6 0.2 2.2 2 0 0 2 2 2 2 Sialic-acid binding micronemal adhesive repeat RSRP PF17069.5 CDJ44212.1 - 0.75 9.3 29.1 0.92 9.0 29.1 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Mucin PF01456.17 CDJ44213.1 - 0.0036 17.3 18.4 0.0036 17.3 18.4 1.9 2 0 0 2 2 2 1 Mucin-like glycoprotein SSP160 PF06933.11 CDJ44213.1 - 0.0046 15.2 14.3 0.0059 14.9 14.3 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 CDJ44213.1 - 0.0062 16.5 14.6 0.014 15.4 14.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) FSA_C PF10479.9 CDJ44213.1 - 0.3 9.2 4.4 0.39 8.8 4.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sporozoite_P67 PF05642.11 CDJ44213.1 - 0.75 7.8 4.1 1 7.4 4.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TMEM154 PF15102.6 CDJ44213.1 - 9.4 6.1 7.6 3.4 7.6 4.9 1.6 2 0 0 2 2 2 0 TMEM154 protein family PP2C PF00481.21 CDJ44214.1 - 3.9e-31 108.6 0.0 1.1e-30 107.1 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ44214.1 - 0.00022 20.9 0.5 0.046 13.4 0.2 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Collagen PF01391.18 CDJ44215.1 - 7.7e-06 25.6 30.6 7.7e-06 25.6 30.6 8.0 7 3 0 7 7 7 1 Collagen triple helix repeat (20 copies) DUF2749 PF10907.8 CDJ44215.1 - 0.89 9.8 3.6 7.7 6.8 2.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Coq4 PF05019.13 CDJ44216.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 TraV PF09676.10 CDJ44216.1 - 0.0038 18.2 1.3 0.0051 17.8 1.3 1.2 1 0 0 1 1 1 1 Type IV conjugative transfer system lipoprotein (TraV) HSP70 PF00012.20 CDJ44218.1 - 3.3e-263 874.3 2.4 3.8e-263 874.1 2.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ44218.1 - 1.5e-14 53.6 0.2 2.2e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CDJ44218.1 - 0.0031 17.3 0.0 0.022 14.5 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 CDJ44218.1 - 0.0047 16.2 0.3 0.013 14.8 0.3 1.8 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase DDR PF08841.10 CDJ44218.1 - 0.0063 15.5 0.5 0.41 9.6 0.3 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain PKK PF12474.8 CDJ44218.1 - 4.1 7.5 6.6 1.9 8.6 2.8 2.0 2 0 0 2 2 2 0 Polo kinase kinase GREB1 PF15782.5 CDJ44219.1 - 3.5 4.6 18.3 4.7 4.2 18.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDV3 PF15359.6 CDJ44220.1 - 0.0049 17.3 3.9 0.0072 16.8 3.9 1.2 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 Spt20 PF12090.8 CDJ44220.1 - 0.62 9.6 7.4 0.91 9.1 7.4 1.3 1 0 0 1 1 1 0 Spt20 family Tic110 PF16940.5 CDJ44220.1 - 5.7 5.3 8.8 7.2 5.0 8.8 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter GREB1 PF15782.5 CDJ44220.1 - 6.8 3.7 12.4 7.7 3.5 12.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer IMUP PF15761.5 CDJ44222.1 - 0.73 10.6 5.6 2 9.2 5.6 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein Ribosomal_60s PF00428.19 CDJ44223.1 - 0.00035 21.1 8.1 0.00035 21.1 8.1 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF3245 PF11595.8 CDJ44223.1 - 0.053 14.0 0.5 0.053 14.0 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Bindin PF02084.15 CDJ44223.1 - 0.3 11.3 10.3 2.1 8.6 0.8 2.1 1 1 1 2 2 2 0 Bindin DUF3138 PF11336.8 CDJ44223.1 - 1.6 7.3 5.0 1.8 7.1 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) VCBS PF13517.6 CDJ44224.1 - 1e-09 38.8 0.3 0.005 17.4 0.0 3.6 3 1 1 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CDJ44224.1 - 1.3e-06 28.4 1.6 8.1e-06 25.9 0.3 3.3 4 0 0 4 4 4 2 FG-GAP repeat TcdB_toxin_midN PF12256.8 CDJ44224.1 - 0.023 14.0 0.0 4.3 6.7 0.0 2.7 3 0 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region DuoxA PF10204.9 CDJ44224.1 - 0.095 11.7 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Dual oxidase maturation factor Spt20 PF12090.8 CDJ44224.1 - 0.12 12.0 22.7 0.37 10.4 10.1 2.2 2 0 0 2 2 2 0 Spt20 family Pex14_N PF04695.13 CDJ44224.1 - 0.43 11.2 13.6 3.1 8.4 4.6 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 CDJ44224.1 - 0.59 9.0 15.4 0.48 9.3 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Pkinase_Tyr PF07714.17 CDJ44225.1 - 0.00045 19.6 0.0 0.00096 18.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ44225.1 - 0.00048 19.6 0.0 0.0018 17.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Spt20 PF12090.8 CDJ44225.1 - 0.00093 18.9 1.5 0.00093 18.9 1.5 1.5 2 0 0 2 2 2 1 Spt20 family GN3L_Grn1 PF08701.11 CDJ44225.1 - 0.08 13.1 1.4 0.15 12.2 1.4 1.4 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase SUIM_assoc PF16619.5 CDJ44225.1 - 6.9 6.8 16.6 0.051 13.6 7.3 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ44225.1 - 10 6.4 0.0 10 6.4 0.0 3.3 1 1 2 3 3 3 0 Anti-sigma-K factor rskA Yae1_N PF09811.9 CDJ44226.1 - 0.0005 19.7 12.3 0.00084 19.0 12.3 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Sod_Fe_C PF02777.18 CDJ44228.1 - 1.8e-31 108.3 0.3 7e-31 106.4 0.0 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CDJ44228.1 - 2.4e-10 40.8 0.1 7.3e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Activator_LAG-3 PF11498.8 CDJ44228.1 - 0.049 12.6 10.2 0.067 12.2 10.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ44228.1 - 3.7 7.5 12.1 4.7 7.1 12.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA PF00004.29 CDJ44229.1 - 1.9e-24 86.6 0.0 3e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ44229.1 - 2.8e-06 27.6 0.2 2.1e-05 24.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ44229.1 - 3.6e-05 24.2 0.6 0.00013 22.4 0.6 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CDJ44229.1 - 0.00019 22.0 0.0 0.0004 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CDJ44229.1 - 0.0018 18.2 0.8 0.019 14.9 0.6 2.4 1 1 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 CDJ44229.1 - 0.0018 18.4 0.0 0.0031 17.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDJ44229.1 - 0.0027 17.7 0.0 0.0045 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ44229.1 - 0.0049 16.6 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 CDJ44229.1 - 0.0077 16.2 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain IstB_IS21 PF01695.17 CDJ44229.1 - 0.0098 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 CDJ44229.1 - 0.01 15.9 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CDJ44229.1 - 0.013 15.9 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 CDJ44229.1 - 0.032 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase TIP49 PF06068.13 CDJ44229.1 - 0.045 13.0 0.0 0.063 12.5 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 CDJ44229.1 - 0.045 13.5 0.0 0.09 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CDJ44229.1 - 0.045 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CDJ44229.1 - 0.065 12.6 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CDJ44229.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CDJ44229.1 - 0.075 13.0 0.1 0.14 12.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 CDJ44229.1 - 0.09 12.7 0.0 4.5 7.1 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 CDJ44229.1 - 0.1 13.0 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDJ44229.1 - 0.1 12.9 0.0 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CDJ44229.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 CDJ44229.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CDJ44229.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.5 1 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CDJ44229.1 - 0.14 11.7 0.1 0.36 10.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain IMUP PF15761.5 CDJ44232.1 - 0.09 13.5 3.8 0.13 13.0 3.8 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein UvrA_DNA-bind PF17755.1 CDJ44233.1 - 0.0016 18.8 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 UvrA DNA-binding domain Transposase_1 PF01359.18 CDJ44233.1 - 0.0025 17.6 0.4 0.0025 17.6 0.4 2.1 1 1 1 2 2 2 1 Transposase (partial DDE domain) Connexin PF00029.19 CDJ44233.1 - 0.19 11.4 2.3 0.19 11.4 2.3 1.0 1 0 0 1 1 1 0 Connexin DUF4834 PF16118.5 CDJ44233.1 - 0.2 12.6 4.1 0.21 12.6 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PET117 PF15786.5 CDJ44233.1 - 0.22 11.8 18.3 0.47 10.7 18.3 1.6 1 1 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial CLN3 PF02487.17 CDJ44233.1 - 0.68 8.9 3.8 0.66 8.9 3.8 1.0 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 CDJ44233.1 - 1.3 7.8 7.8 1.4 7.6 7.8 1.0 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ44233.1 - 2.7 7.5 26.3 2.9 7.5 26.3 1.1 1 0 0 1 1 1 0 Spt20 family DUF4407 PF14362.6 CDJ44233.1 - 5.5 6.3 10.3 6.2 6.1 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 CDJ44233.1 - 6.8 6.6 23.7 6.9 6.6 23.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF900 PF05990.12 CDJ44234.1 - 7.2e-17 61.7 0.0 8.2e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 CDJ44234.1 - 0.015 15.9 0.0 0.02 15.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Spt20 PF12090.8 CDJ44235.1 - 7 6.2 9.9 9.7 5.7 9.9 1.1 1 0 0 1 1 1 0 Spt20 family Pep3_Vps18 PF05131.14 CDJ44236.1 - 1.5e-14 54.0 0.0 4.9e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CDJ44236.1 - 1.9e-06 27.8 0.0 1e-05 25.4 0.0 2.3 1 0 0 1 1 1 1 Region in Clathrin and VPS Vps39_2 PF10367.9 CDJ44236.1 - 1e-05 25.9 1.9 2.6e-05 24.6 1.9 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3H2C3 PF17122.5 CDJ44236.1 - 0.023 14.7 5.3 0.055 13.5 5.3 1.6 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 CDJ44236.1 - 0.075 12.7 6.0 0.23 11.1 6.0 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type YqfQ PF14181.6 CDJ44237.1 - 0.21 11.8 7.2 0.28 11.4 7.2 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF2052 PF09747.9 CDJ44237.1 - 1.2 9.2 7.7 1.7 8.7 7.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) tRNA-synt_2 PF00152.20 CDJ44239.1 - 1.2e-34 119.9 0.0 1.3e-34 119.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CDJ44239.1 - 0.05 13.1 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) SOUL PF04832.12 CDJ44241.1 - 2.4e-30 105.9 0.0 5.7e-29 101.4 0.0 2.1 1 1 0 1 1 1 1 SOUL heme-binding protein RRM_1 PF00076.22 CDJ44242.1 - 0.00017 21.4 0.0 0.00043 20.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF359 PF04019.12 CDJ44242.1 - 0.056 13.1 0.2 0.056 13.1 0.2 2.5 3 1 1 4 4 4 0 Protein of unknown function (DUF359) KAR9 PF08580.10 CDJ44242.1 - 9.3 4.7 28.7 16 3.9 28.7 1.4 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TFIIA PF03153.13 CDJ44243.1 - 1.6 8.6 37.4 2 8.3 37.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ44243.1 - 1.9 6.9 45.7 2.7 6.5 45.7 1.2 1 0 0 1 1 1 0 Macoilin family Med7 PF05983.11 CDJ44244.1 - 4.4e-12 46.5 0.1 6.2e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 MED7 protein Med4 PF10018.9 CDJ44244.1 - 0.026 14.2 3.9 0.037 13.7 3.9 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 UIM PF02809.20 CDJ44244.1 - 0.048 13.6 2.9 0.091 12.7 0.5 2.5 1 1 1 2 2 2 0 Ubiquitin interaction motif Herpes_LMP1 PF05297.11 CDJ44244.1 - 0.13 11.4 0.2 0.17 11.0 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) FUSC PF04632.12 CDJ44244.1 - 0.16 10.5 11.4 0.2 10.1 11.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2946 PF11162.8 CDJ44245.1 - 0.16 12.6 0.1 0.16 12.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) SUIM_assoc PF16619.5 CDJ44245.1 - 0.39 10.8 9.4 0.64 10.1 9.4 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 EphA2_TM PF14575.6 CDJ44245.1 - 0.46 11.4 2.2 19 6.2 0.1 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Inj_translocase PF16928.5 CDJ44245.1 - 1.2 8.6 5.9 1.7 8.0 5.9 1.2 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome Spc7 PF08317.11 CDJ44246.1 - 0.0026 16.7 10.1 0.0034 16.3 10.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Tup_N PF08581.10 CDJ44246.1 - 0.0066 16.7 6.2 0.011 16.0 6.2 1.4 1 0 0 1 1 1 1 Tup N-terminal EzrA PF06160.12 CDJ44246.1 - 0.019 13.2 7.2 0.025 12.8 7.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Herpes_UL6 PF01763.16 CDJ44246.1 - 0.24 9.9 2.8 0.28 9.7 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Pil1 PF13805.6 CDJ44246.1 - 0.27 10.7 8.5 0.88 9.0 8.3 1.7 1 1 1 2 2 2 0 Eisosome component PIL1 Tim17 PF02466.19 CDJ44246.1 - 0.7 10.3 4.2 2.4 8.6 3.4 2.0 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family TMPIT PF07851.13 CDJ44246.1 - 1.8 7.7 4.4 2.4 7.3 4.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein CENP-H PF05837.12 CDJ44246.1 - 2.2 8.7 7.9 3.6 8.0 7.9 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) HTH_29 PF13551.6 CDJ44247.1 - 0.013 15.5 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Flg_hook PF02120.16 CDJ44247.1 - 0.33 10.9 4.1 1.3 8.9 0.0 2.8 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK Ribosomal_60s PF00428.19 CDJ44247.1 - 0.33 11.6 6.5 0.6 10.7 6.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Arm PF00514.23 CDJ44248.1 - 0.029 14.4 1.3 5.8 7.1 0.3 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat TFIIA PF03153.13 CDJ44248.1 - 0.24 11.4 25.3 0.33 10.9 25.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HEAT PF02985.22 CDJ44248.1 - 0.51 10.7 3.1 0.96 9.9 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat UPF0565 PF10561.9 CDJ44248.1 - 1.6 7.8 5.8 2.5 7.2 5.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 PAT1 PF09770.9 CDJ44248.1 - 2.7 6.1 17.6 3.4 5.8 17.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 CDJ44248.1 - 4.4 6.0 6.4 6.1 5.5 6.4 1.1 1 0 0 1 1 1 0 Presenilin Toprim PF01751.22 CDJ44249.1 - 0.00016 21.8 0.0 0.0003 21.0 0.0 1.4 1 0 0 1 1 1 1 Toprim domain DUF3498 PF12004.8 CDJ44249.1 - 0.0033 16.7 8.4 0.0039 16.5 8.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3498) ASFV_J13L PF05568.11 CDJ44249.1 - 9.6 5.9 10.7 12 5.6 9.3 1.7 2 0 0 2 2 2 0 African swine fever virus J13L protein vMSA PF00695.19 CDJ44250.1 - 0.071 12.2 0.2 0.081 12.0 0.2 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus SR-25 PF10500.9 CDJ44251.1 - 2 8.0 6.0 3.1 7.4 6.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 CDJ44251.1 - 2.3 9.1 9.8 0.67 10.8 2.0 2.2 2 0 0 2 2 2 0 Chorion family 2 NTP_transf_2 PF01909.23 CDJ44252.1 - 5.4e-05 23.4 0.0 8.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CDJ44252.1 - 0.0021 18.1 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase RskA PF10099.9 CDJ44252.1 - 0.014 15.7 2.0 0.018 15.4 2.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Med21 PF11221.8 CDJ44252.1 - 0.026 14.8 0.1 0.039 14.2 0.1 1.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex PSD4 PF07631.11 CDJ44252.1 - 0.06 13.9 0.4 0.25 11.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) MMR_HSR1 PF01926.23 CDJ44253.1 - 5.5e-16 58.7 0.0 9.2e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ44253.1 - 0.00085 19.3 0.9 0.72 9.7 0.0 3.0 2 1 1 3 3 3 1 RsgA GTPase TrmE_N PF10396.9 CDJ44253.1 - 0.001 19.4 0.2 0.0044 17.3 0.0 2.2 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus Dynamin_N PF00350.23 CDJ44253.1 - 0.0014 18.8 0.2 0.0059 16.7 0.2 2.1 1 1 0 1 1 1 1 Dynamin family Gtr1_RagA PF04670.12 CDJ44253.1 - 0.0043 16.4 0.0 0.075 12.4 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region LCD1 PF09798.9 CDJ44253.1 - 0.018 13.6 0.0 0.027 13.0 0.0 1.3 1 1 0 1 1 1 0 DNA damage checkpoint protein SRPRB PF09439.10 CDJ44253.1 - 0.027 13.9 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 CDJ44253.1 - 0.043 14.3 0.1 0.043 14.3 0.1 2.2 2 1 0 2 2 2 0 ABC transporter FeoB_N PF02421.18 CDJ44253.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 CDJ44253.1 - 0.078 12.7 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 CDJ44253.1 - 0.13 11.7 3.4 0.19 11.1 0.0 2.4 3 0 0 3 3 3 0 Bacterial TniB protein Allexi_40kDa PF05549.11 CDJ44253.1 - 0.24 10.9 2.0 0.5 9.8 1.3 1.8 2 0 0 2 2 2 0 Allexivirus 40kDa protein Miga PF10265.9 CDJ44253.1 - 1.5 7.7 5.9 2.4 7.0 4.3 1.9 2 0 0 2 2 2 0 Mitoguardin DUF4208 PF13907.6 CDJ44253.1 - 1.9 9.0 6.9 0.37 11.3 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) LMBR1 PF04791.16 CDJ44254.1 - 0.0014 17.7 0.1 0.0014 17.7 0.1 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein dsDNA_bind PF01984.20 CDJ44255.1 - 4.4e-21 75.2 12.1 5.3e-21 75.0 12.1 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4953 PF16313.5 CDJ44255.1 - 0.02 14.1 2.4 0.025 13.8 2.4 1.1 1 0 0 1 1 1 0 Met-zincin DUF4711 PF15829.5 CDJ44255.1 - 0.046 13.7 1.2 0.056 13.4 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) RRP14 PF15459.6 CDJ44255.1 - 0.28 11.8 6.5 7.3 7.3 4.7 2.3 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 CcdA PF07362.12 CDJ44255.1 - 1.5 9.3 7.3 0.84 10.1 2.6 2.2 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA GTA_holin_3TM PF11351.8 CDJ44255.1 - 6.1 7.4 10.7 6.5 7.3 9.6 1.7 1 1 1 2 2 2 0 Holin of 3TMs, for gene-transfer release DUF3886 PF13025.6 CDJ44255.1 - 9 6.6 17.4 11 6.3 12.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3886) CHD5 PF04420.14 CDJ44256.1 - 1.1e-07 31.9 5.7 2e-07 31.0 5.7 1.4 1 0 0 1 1 1 1 CHD5-like protein Lin-8 PF03353.15 CDJ44256.1 - 0.076 12.6 7.8 0.12 11.9 7.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 CDJ44256.1 - 0.11 12.4 10.7 0.092 12.7 8.7 1.7 2 0 0 2 2 2 0 SPX domain CAP59_mtransfer PF11735.8 CDJ44256.1 - 0.12 12.0 2.1 0.21 11.2 2.1 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 CCSAP PF15748.5 CDJ44256.1 - 0.17 12.0 13.6 0.025 14.7 3.6 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated V_ATPase_I PF01496.19 CDJ44256.1 - 0.5 8.2 4.6 0.64 7.9 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S46 PF10459.9 CDJ44256.1 - 0.62 8.6 6.8 0.75 8.4 6.8 1.1 1 0 0 1 1 1 0 Peptidase S46 OmpH PF03938.14 CDJ44256.1 - 0.83 10.0 19.8 2 8.8 19.8 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Bud13 PF09736.9 CDJ44256.1 - 2.2 8.7 6.2 3.4 8.1 6.2 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex FapA PF03961.13 CDJ44256.1 - 3.8 6.0 4.9 5 5.6 4.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Activator_LAG-3 PF11498.8 CDJ44256.1 - 5.9 5.7 29.7 9.7 5.0 29.7 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Cpn60_TCP1 PF00118.24 CDJ44257.1 - 1.3e-46 159.3 3.3 2.8e-28 98.8 0.2 2.8 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family ABC_tran PF00005.27 CDJ44258.1 - 4.1e-16 59.7 0.0 1.7e-15 57.8 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ44258.1 - 2.5e-07 30.8 0.4 0.0085 15.9 0.1 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ44258.1 - 3.9e-07 29.7 0.2 0.0014 18.1 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CDJ44258.1 - 0.0009 19.5 0.0 0.0025 18.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDJ44258.1 - 0.0015 18.3 0.1 0.003 17.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CDJ44258.1 - 0.0034 17.1 0.0 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ44258.1 - 0.0053 16.7 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CDJ44258.1 - 0.0065 16.9 0.0 0.0095 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 CDJ44258.1 - 0.0089 16.5 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CDJ44258.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 CDJ44258.1 - 0.081 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 CDJ44258.1 - 0.086 12.9 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 CDJ44258.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CDJ44258.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CDJ44258.1 - 0.16 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CDJ44258.1 - 0.17 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 CDJ44258.1 - 0.19 10.8 0.1 0.71 9.0 0.0 1.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_13 PF13166.6 CDJ44258.1 - 0.21 10.2 0.0 0.35 9.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain SHE3 PF17078.5 CDJ44261.1 - 0.022 14.5 0.6 0.022 14.5 0.6 1.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 EzrA PF06160.12 CDJ44261.1 - 0.029 12.5 0.8 0.04 12.1 0.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA FlxA PF14282.6 CDJ44261.1 - 2.2 8.3 4.8 1.1 9.3 1.0 2.1 2 1 0 2 2 2 0 FlxA-like protein Activator_LAG-3 PF11498.8 CDJ44263.1 - 0.0036 16.3 24.7 0.0036 16.3 24.7 3.2 3 0 0 3 3 3 1 Transcriptional activator LAG-3 Sin_N PF04801.13 CDJ44263.1 - 0.0038 16.5 17.6 0.0038 16.5 17.6 2.3 2 0 0 2 2 2 1 Sin-like protein conserved region EPL1 PF10513.9 CDJ44263.1 - 0.35 11.2 18.9 0.96 9.8 2.4 3.3 3 0 0 3 3 3 0 Enhancer of polycomb-like Hist_deacetyl PF00850.19 CDJ44263.1 - 2 7.8 13.9 0.65 9.4 1.8 2.7 3 0 0 3 3 3 0 Histone deacetylase domain CT_C_D PF02682.16 CDJ44263.1 - 4.4 7.0 18.9 2.5 7.8 4.6 3.5 3 0 0 3 3 3 0 Carboxyltransferase domain, subdomain C and D Tmp39 PF10271.9 CDJ44263.1 - 4.6 6.1 5.4 8.2 5.3 5.1 1.6 1 1 0 1 1 1 0 Putative transmembrane protein DUF2072 PF09845.9 CDJ44263.1 - 4.9 7.4 10.6 0.67 10.2 0.5 3.1 3 0 0 3 3 3 0 Zn-ribbon containing protein DUF1980 PF09323.10 CDJ44263.1 - 9.3 6.1 12.5 0.29 11.0 0.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Ribosomal_S18 PF01084.20 CDJ44265.1 - 6.4e-12 45.5 0.0 6.4e-12 45.5 0.0 2.6 3 0 0 3 3 3 1 Ribosomal protein S18 TFIIA PF03153.13 CDJ44265.1 - 0.0026 17.8 17.9 0.0035 17.4 17.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FlxA PF14282.6 CDJ44265.1 - 0.086 12.8 27.3 0.16 11.9 27.3 1.4 1 0 0 1 1 1 0 FlxA-like protein Ndc1_Nup PF09531.10 CDJ44265.1 - 0.38 9.4 7.3 0.41 9.3 7.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup YabA PF06156.13 CDJ44265.1 - 0.69 10.6 5.5 2.1 9.0 3.9 2.1 2 0 0 2 2 2 0 Initiation control protein YabA DUF3138 PF11336.8 CDJ44265.1 - 4.5 5.8 6.4 6.2 5.3 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spt20 PF12090.8 CDJ44265.1 - 6.9 6.2 23.6 10 5.7 23.6 1.2 1 0 0 1 1 1 0 Spt20 family Metallophos PF00149.28 CDJ44266.1 - 2.3e-19 70.7 0.0 3e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 CDJ44266.1 - 0.028 14.1 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Transglut_core3 PF13471.6 CDJ44267.1 - 1.8 8.5 7.9 0.62 10.0 0.2 2.6 3 0 0 3 3 3 0 Transglutaminase-like superfamily Tristanin_u2 PF16638.5 CDJ44267.1 - 6.4 7.6 6.3 83 4.0 4.3 2.7 2 1 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers NUC130_3NT PF08158.12 CDJ44268.1 - 1.2e-07 31.9 2.6 0.003 17.8 0.5 3.2 3 0 0 3 3 3 2 NUC130/3NT domain Spt20 PF12090.8 CDJ44269.1 - 0.028 14.1 10.3 0.03 13.9 10.3 1.2 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ44269.1 - 0.037 14.3 11.5 0.047 14.0 11.5 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA IHABP4_N PF16174.5 CDJ44269.1 - 0.23 12.0 7.7 0.28 11.8 7.7 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal WES_acyltransf PF03007.16 CDJ44269.1 - 0.24 11.1 5.7 0.28 10.9 5.7 1.1 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Roughex PF06020.11 CDJ44269.1 - 0.3 10.1 5.3 0.32 10.1 5.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Shadoo PF14999.6 CDJ44269.1 - 0.38 10.9 14.5 0.22 11.6 12.9 1.4 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective TFIIA PF03153.13 CDJ44269.1 - 0.69 9.8 17.6 0.75 9.7 17.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DLIC PF05783.11 CDJ44271.1 - 1.5e-05 24.0 0.0 1.5e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 CDJ44271.1 - 0.0056 17.0 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 CDJ44271.1 - 0.021 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Glyco_hydro_88 PF07470.13 CDJ44271.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 AAA_28 PF13521.6 CDJ44271.1 - 0.037 14.3 0.1 0.037 14.3 0.1 2.7 2 2 1 3 3 3 0 AAA domain AAA_18 PF13238.6 CDJ44271.1 - 0.062 13.8 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 CDJ44271.1 - 0.065 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_14 PF13173.6 CDJ44271.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 CDJ44271.1 - 0.15 12.2 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TFIIA PF03153.13 CDJ44271.1 - 4.6 7.1 16.3 11 5.9 13.5 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Aminotran_1_2 PF00155.21 CDJ44272.1 - 3e-62 210.9 0.0 3e-62 210.9 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CDJ44272.1 - 7.2e-08 31.4 0.0 1.1e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CDJ44272.1 - 0.0006 18.9 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CDJ44272.1 - 0.0029 16.9 0.0 0.0035 16.7 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CDJ44272.1 - 0.077 12.3 0.6 0.72 9.1 0.6 2.2 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family FlxA PF14282.6 CDJ44272.1 - 1 9.4 18.9 3.6 7.6 0.3 2.5 2 0 0 2 2 2 0 FlxA-like protein Ribosomal_60s PF00428.19 CDJ44272.1 - 1.6 9.4 8.2 4.6 7.9 7.4 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf_CCCH_4 PF18345.1 CDJ44273.1 - 1.8e-13 50.0 20.1 1.7e-06 27.9 1.8 4.2 4 0 0 4 4 4 3 Zinc finger domain zf-CCCH PF00642.24 CDJ44273.1 - 7e-13 48.1 15.3 4e-08 33.0 1.6 4.2 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CDJ44273.1 - 0.00015 22.0 9.5 0.00034 20.8 4.7 2.2 1 1 1 2 2 2 2 Zinc-finger containing family Torus PF16131.5 CDJ44273.1 - 0.00016 22.3 15.3 0.14 12.9 1.3 3.1 1 1 2 3 3 3 3 Torus domain zf-CCCH_4 PF18044.1 CDJ44273.1 - 0.00097 18.9 18.3 0.0018 18.0 1.7 4.1 3 2 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CDJ44273.1 - 0.0013 19.1 14.3 0.42 11.1 0.4 3.3 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 CDJ44273.1 - 0.0026 17.5 10.0 0.0087 15.8 0.2 3.4 3 1 0 3 3 3 2 Putative zinc-finger domain UPAR_LY6 PF00021.21 CDJ44273.1 - 0.44 11.3 10.0 0.63 10.8 1.9 2.8 1 1 1 2 2 2 0 u-PAR/Ly-6 domain Lustrin_cystein PF14625.6 CDJ44273.1 - 3 8.3 14.2 6.9 7.1 1.0 3.1 1 1 2 3 3 3 0 Lustrin, cysteine-rich repeated domain Acetyltransf_1 PF00583.25 CDJ44274.1 - 1.4e-07 31.8 0.0 2.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ44274.1 - 7.4e-07 29.2 0.6 9.1e-07 28.9 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ44274.1 - 2.5e-05 24.6 0.0 4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ44274.1 - 0.0042 17.0 0.0 0.0084 16.0 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Spt20 PF12090.8 CDJ44274.1 - 0.1 12.2 10.2 0.11 12.1 10.2 1.1 1 0 0 1 1 1 0 Spt20 family TMEM208_SND2 PF05620.11 CDJ44274.1 - 8.4 6.1 7.9 11 5.8 7.9 1.3 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 IF-2B PF01008.17 CDJ44276.1 - 1.2e-12 47.7 0.0 1.3e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family GCP_C_terminal PF04130.13 CDJ44277.1 - 0.0025 17.3 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Peptidase_S8 PF00082.22 CDJ44277.1 - 0.032 13.5 0.1 0.037 13.3 0.1 1.0 1 0 0 1 1 1 0 Subtilase family DUF2722 PF10846.8 CDJ44277.1 - 0.074 12.0 1.9 0.082 11.8 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ44277.1 - 0.37 9.7 12.3 0.46 9.4 12.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SUIM_assoc PF16619.5 CDJ44277.1 - 0.59 10.2 15.7 0.9 9.6 1.7 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ44277.1 - 0.82 9.2 6.5 1 8.9 6.5 1.2 1 0 0 1 1 1 0 Spt20 family HhH-GPD PF00730.25 CDJ44279.1 - 1e-05 25.9 0.0 1.5e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF2400 PF09674.10 CDJ44279.1 - 0.12 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) EndIII_4Fe-2S PF10576.9 CDJ44279.1 - 0.16 12.3 2.4 0.16 12.3 2.4 2.2 3 0 0 3 3 3 0 Iron-sulfur binding domain of endonuclease III GDA1_CD39 PF01150.17 CDJ44280.1 - 0.0066 15.2 0.0 0.029 13.0 0.0 1.8 2 0 0 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family Trypan_PARP PF05887.11 CDJ44280.1 - 6.2 6.8 11.9 18 5.3 11.9 1.8 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Myb_DNA-bind_7 PF15963.5 CDJ44283.1 - 0.00046 20.0 0.2 0.00046 20.0 0.2 1.7 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CDJ44283.1 - 0.0064 16.7 0.0 0.0096 16.1 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain GNAT_C PF18164.1 CDJ44283.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 GNAT-like C-terminal domain Thioredoxin_6 PF13848.6 CDJ44284.1 - 8.8e-06 25.8 0.0 0.00029 20.8 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin PF00085.20 CDJ44284.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin AbiEi_2 PF09952.9 CDJ44284.1 - 0.15 12.3 2.9 16 5.7 0.8 2.8 2 1 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system PAF PF15715.5 CDJ44285.1 - 6.6 7.3 9.1 6.8 7.3 2.2 2.2 2 0 0 2 2 2 0 PCNA-associated factor histone like domain Filament_head PF04732.14 CDJ44285.1 - 9.8 7.1 27.9 7 7.6 9.0 2.4 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region zf-CCCH PF00642.24 CDJ44289.1 - 3.3e-08 33.3 6.7 5e-08 32.7 6.7 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ44289.1 - 0.01 15.6 5.8 0.015 15.1 5.8 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDJ44289.1 - 0.049 13.7 8.0 0.091 12.8 8.0 1.5 1 0 0 1 1 1 0 Zinc finger domain Abhydrolase_1 PF00561.20 CDJ44291.1 - 2.4e-14 53.6 0.1 2.8e-14 53.4 0.1 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 CDJ44291.1 - 0.0022 16.7 0.0 0.0027 16.4 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.7 CDJ44291.1 - 0.0085 16.7 0.0 0.0091 16.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ44291.1 - 0.12 11.7 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SUIM_assoc PF16619.5 CDJ44291.1 - 0.91 9.6 9.5 2 8.5 9.5 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ44291.1 - 3.1 7.3 7.7 5.4 6.6 7.7 1.3 1 0 0 1 1 1 0 Spt20 family DUF4175 PF13779.6 CDJ44293.1 - 0.8 7.5 6.9 0.86 7.4 6.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Trypan_PARP PF05887.11 CDJ44294.1 - 0.36 10.8 7.0 0.54 10.2 7.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AAA_23 PF13476.6 CDJ44295.1 - 2.4e-10 41.3 0.1 3.5e-10 40.7 0.1 1.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 CDJ44295.1 - 3.7e-08 33.1 0.1 4.2e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ44295.1 - 0.012 15.4 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Med3 PF11593.8 CDJ44295.1 - 0.014 14.6 1.7 0.016 14.5 1.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_15 PF13175.6 CDJ44295.1 - 0.033 13.9 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF2656 PF10847.8 CDJ44295.1 - 0.034 14.3 0.0 0.044 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) SMC_N PF02463.19 CDJ44297.1 - 1.2e-08 34.7 0.0 2.7e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CDJ44297.1 - 4 7.7 8.9 0.45 10.8 0.2 4.0 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit THP2 PF09432.10 CDJ44297.1 - 9.2 6.3 14.8 0.067 13.2 3.1 3.1 2 1 0 2 2 2 0 Tho complex subunit THP2 COG4 PF08318.12 CDJ44298.1 - 7.8e-10 38.3 0.0 9.2e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 COG4 transport protein TraF PF13728.6 CDJ44298.1 - 0.051 13.4 1.6 0.072 12.9 1.6 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF1180 PF06679.12 CDJ44298.1 - 0.13 12.7 0.5 0.16 12.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PmbA_TldD PF01523.16 CDJ44298.1 - 0.13 12.1 0.3 0.16 11.8 0.3 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Dymeclin PF09742.9 CDJ44299.1 - 0.012 14.1 3.4 0.013 13.9 3.4 1.0 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein Aquarius_N PF16399.5 CDJ44299.1 - 0.58 8.1 7.3 0.69 7.9 7.3 1.1 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus ABATE PF07336.11 CDJ44299.1 - 7.7 7.2 15.4 38 4.9 15.4 1.9 1 1 0 1 1 1 0 Putative stress-induced transcription regulator CRISPR_Cse2 PF09485.10 CDJ44299.1 - 9.8 6.7 15.3 3.9 8.0 8.6 2.2 1 1 1 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF900 PF05990.12 CDJ44300.1 - 0.019 14.5 0.0 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Spt20 PF12090.8 CDJ44300.1 - 0.075 12.6 4.1 0.07 12.7 4.1 1.1 1 0 0 1 1 1 0 Spt20 family GSH_synth_ATP PF03917.17 CDJ44301.1 - 1.8e-28 99.4 0.5 3.5e-28 98.4 0.5 1.5 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain MOSC_N PF03476.16 CDJ44301.1 - 0.27 11.1 1.8 1.1 9.1 0.3 2.3 2 0 0 2 2 2 0 MOSC N-terminal beta barrel domain Spt20 PF12090.8 CDJ44301.1 - 0.55 9.8 10.2 0.23 11.0 4.9 2.2 2 0 0 2 2 2 0 Spt20 family Ribosomal_60s PF00428.19 CDJ44301.1 - 2.2 8.9 22.6 7 7.3 10.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2722 PF10846.8 CDJ44301.1 - 4 6.3 13.1 13 4.6 13.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2722) YqfQ PF14181.6 CDJ44301.1 - 6.4 6.9 9.9 0.15 12.3 1.5 2.3 3 0 0 3 3 3 0 YqfQ-like protein hDGE_amylase PF14701.6 CDJ44303.1 - 2.9e-17 62.9 0.0 3.6e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain SUIM_assoc PF16619.5 CDJ44303.1 - 0.0031 17.5 2.6 0.005 16.9 2.6 1.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ44304.1 - 0.25 11.3 15.3 0.34 10.9 15.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ44304.1 - 0.37 9.3 8.6 0.44 9.1 8.6 1.1 1 0 0 1 1 1 0 Macoilin family Ofd1_CTDD PF10637.9 CDJ44304.1 - 1.4 8.2 4.0 2.3 7.5 3.9 1.2 1 1 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term PAT1 PF09770.9 CDJ44304.1 - 5.5 5.1 9.2 6.3 4.9 9.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SID-1_RNA_chan PF13965.6 CDJ44305.1 - 0.78 8.1 7.0 1.9 6.8 7.0 1.6 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Helicase_C_2 PF13307.6 CDJ44307.1 - 6.6e-10 39.4 0.0 8.5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain zf-RING_UBOX PF13445.6 CDJ44308.1 - 2e-05 24.5 9.7 2e-05 24.5 9.7 2.2 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ44308.1 - 5.9e-05 22.9 7.6 5.9e-05 22.9 7.6 2.6 2 0 0 2 2 2 1 zinc-RING finger domain SUIM_assoc PF16619.5 CDJ44308.1 - 0.0015 18.6 0.4 0.0015 18.6 0.4 3.2 2 1 1 3 3 2 1 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ44308.1 - 0.002 18.4 23.7 0.0053 17.1 2.7 2.5 1 1 1 2 2 2 1 Anti-sigma-K factor rskA zf-C3HC4 PF00097.25 CDJ44308.1 - 0.0027 17.6 8.1 0.0027 17.6 8.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FmiP_Thoc5 PF09766.9 CDJ44308.1 - 0.0069 15.7 5.1 0.0069 15.7 5.1 2.1 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 zf-RING_2 PF13639.6 CDJ44308.1 - 0.018 15.4 11.7 0.018 15.4 11.7 2.4 2 0 0 2 2 2 0 Ring finger domain ANAPC_CDC26 PF10471.9 CDJ44308.1 - 0.04 14.7 3.2 0.04 14.7 3.2 3.5 4 0 0 4 4 3 0 Anaphase-promoting complex APC subunit CDC26 Pro_CA PF00484.19 CDJ44308.1 - 0.25 11.6 0.1 0.25 11.6 0.1 2.4 2 0 0 2 2 2 0 Carbonic anhydrase Spt20 PF12090.8 CDJ44308.1 - 0.48 10.0 30.7 0.11 12.0 4.7 2.1 2 0 0 2 2 2 0 Spt20 family Connexin PF00029.19 CDJ44308.1 - 0.6 9.8 4.4 1.6 8.4 1.5 2.3 2 0 0 2 2 2 0 Connexin SpoIIP PF07454.11 CDJ44308.1 - 0.67 9.4 5.3 1.4 8.3 1.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Pet20 PF08692.10 CDJ44308.1 - 1.1 9.9 3.2 15 6.3 2.0 2.1 2 0 0 2 2 2 0 Mitochondrial protein Pet20 eIF-3_zeta PF05091.12 CDJ44308.1 - 1.2 8.0 11.3 1.4 7.8 5.7 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Afi1 PF07792.12 CDJ44308.1 - 1.5 9.3 7.3 21 5.6 6.0 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking zf-C3HC4_4 PF15227.6 CDJ44308.1 - 1.6 8.9 19.5 0.048 13.8 10.2 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4834 PF16118.5 CDJ44308.1 - 2.1 9.3 13.3 5.7 8.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Rtf2 PF04641.12 CDJ44308.1 - 2.4 7.4 14.9 1.6 8.0 6.4 2.4 1 1 1 2 2 2 0 Rtf2 RING-finger TERB2 PF15101.6 CDJ44308.1 - 4.5 7.3 15.0 2.1 8.4 5.2 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Baculo_PP31 PF05311.11 CDJ44308.1 - 5.7 6.4 9.4 21 4.5 5.4 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) DUF2722 PF10846.8 CDJ44308.1 - 5.9 5.7 25.5 0.17 10.8 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4140 PF13600.6 CDJ44308.1 - 8.5 6.9 20.4 0.23 11.9 0.4 3.2 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) FliD_N PF02465.18 CDJ44308.1 - 8.7 7.1 21.0 0.93 10.2 4.8 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DivIC PF04977.15 CDJ44308.1 - 9.9 6.0 29.1 22 4.9 0.0 3.3 3 0 0 3 3 3 0 Septum formation initiator SMYLE_N PF18615.1 CDJ44309.1 - 0.012 15.2 4.1 0.017 14.7 4.1 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF4179 PF13786.6 CDJ44309.1 - 0.042 14.3 0.2 0.054 14.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Spt20 PF12090.8 CDJ44309.1 - 0.52 9.9 11.6 0.45 10.1 11.6 1.2 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ44309.1 - 3.8 7.8 12.6 6.2 7.1 12.6 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA KCNQ2_u3 PF16642.5 CDJ44309.1 - 6.1 7.9 14.0 2.3 9.2 6.5 2.0 1 1 1 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 TFIIA PF03153.13 CDJ44309.1 - 6.8 6.6 18.5 7.2 6.5 18.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ44311.1 - 0.58 8.0 11.9 0.66 7.8 11.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 CDJ44311.1 - 1.1 8.7 21.6 1.5 8.3 21.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DinB_2 PF12867.7 CDJ44311.1 - 5.1 7.6 9.2 0.87 10.1 3.8 2.2 1 1 1 2 2 2 0 DinB superfamily AAA_13 PF13166.6 CDJ44311.1 - 8.7 4.8 20.0 11 4.5 20.0 1.0 1 0 0 1 1 1 0 AAA domain UPF0242 PF06785.11 CDJ44311.1 - 9.5 6.3 28.4 16 5.5 0.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LON_substr_bdg PF02190.16 CDJ44312.1 - 1.9e-15 57.3 0.5 3.3e-14 53.2 0.0 2.4 2 1 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain TFIIA PF03153.13 CDJ44312.1 - 1.8e-05 25.0 22.6 1.8e-05 25.0 22.6 1.9 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ44312.1 - 0.00078 18.1 21.5 0.0012 17.5 21.5 1.2 1 0 0 1 1 1 1 Macoilin family SpoIIP PF07454.11 CDJ44312.1 - 0.0071 15.8 8.9 0.012 15.1 8.9 1.3 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Ndc1_Nup PF09531.10 CDJ44312.1 - 0.18 10.5 13.4 0.29 9.8 13.4 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IHABP4_N PF16174.5 CDJ44312.1 - 0.23 12.1 30.2 3.7 8.1 25.7 2.4 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal SPX PF03105.19 CDJ44312.1 - 0.45 10.4 21.8 0.82 9.5 19.3 2.2 2 0 0 2 2 2 0 SPX domain Peptidase_S64 PF08192.11 CDJ44312.1 - 0.49 8.8 15.4 0.65 8.4 15.4 1.2 1 0 0 1 1 1 0 Peptidase family S64 Plasmodium_Vir PF05795.11 CDJ44312.1 - 0.83 9.0 8.0 1.7 8.0 8.0 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RR_TM4-6 PF06459.12 CDJ44312.1 - 1.1 9.0 15.1 2.4 7.9 15.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 CDJ44312.1 - 1.8 5.6 22.2 2.4 5.2 22.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ44312.1 - 2.4 6.3 26.1 0.19 9.9 21.5 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.10 CDJ44312.1 - 7.4 5.1 36.3 0.25 10.0 28.7 1.9 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Draxin PF15550.6 CDJ44312.1 - 7.7 6.3 13.3 14 5.4 13.3 1.3 1 0 0 1 1 1 0 Draxin PSD4 PF07631.11 CDJ44313.1 - 0.097 13.2 0.4 0.11 13.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) Secretin_N PF03958.17 CDJ44313.1 - 0.37 11.2 3.2 0.53 10.7 3.2 1.2 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain Androgen_recep PF02166.16 CDJ44314.1 - 0.003 16.5 5.8 0.0038 16.1 5.8 1.1 1 0 0 1 1 1 1 Androgen receptor DUF4643 PF15485.6 CDJ44314.1 - 0.042 13.7 3.4 0.049 13.5 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) DUF4603 PF15376.6 CDJ44314.1 - 0.1 10.0 7.3 0.11 9.9 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) SRC-1 PF08832.10 CDJ44314.1 - 0.11 13.6 1.1 0.11 13.6 1.1 2.1 1 1 1 2 2 2 0 Steroid receptor coactivator TetR_C_23 PF17931.1 CDJ44314.1 - 0.18 12.0 1.4 0.29 11.3 1.4 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Angiomotin_C PF12240.8 CDJ44314.1 - 0.19 11.3 7.9 0.27 10.8 7.8 1.3 1 1 0 1 1 1 0 Angiomotin C terminal Raftlin PF15250.6 CDJ44314.1 - 0.68 8.6 5.5 0.79 8.4 5.5 1.0 1 0 0 1 1 1 0 Raftlin FlxA PF14282.6 CDJ44314.1 - 4.1 7.5 20.7 0.034 14.1 10.5 2.1 2 0 0 2 2 2 0 FlxA-like protein DUF4692 PF15763.5 CDJ44314.1 - 4.1 7.8 14.0 0.67 10.4 2.3 2.1 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) SUZ PF12752.7 CDJ44314.1 - 7.1 7.5 9.3 3.9 8.3 1.1 2.3 2 0 0 2 2 2 0 SUZ domain DUF3446 PF11928.8 CDJ44314.1 - 7.6 6.9 19.6 5.5 7.4 7.8 2.2 1 1 1 2 2 2 0 Early growth response N-terminal domain RskA PF10099.9 CDJ44315.1 - 0.0017 18.7 3.2 0.0017 18.7 3.2 3.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ44315.1 - 0.47 9.2 5.2 0.39 9.4 2.3 2.0 2 0 0 2 2 2 0 Presenilin PBP1_TM PF14812.6 CDJ44315.1 - 10 6.6 7.3 28 5.2 0.2 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_pol_I_TF PF04090.12 CDJ44316.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor zf-RING_2 PF13639.6 CDJ44317.1 - 1.3e-11 44.6 1.0 2.8e-11 43.6 0.3 1.7 1 1 1 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CDJ44317.1 - 4.5e-11 42.3 2.6 4.5e-11 42.3 2.6 1.5 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CDJ44317.1 - 1.2e-09 38.1 0.4 1.2e-09 38.1 0.4 1.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ44317.1 - 1.3e-07 31.3 0.7 1.8e-07 30.8 0.2 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ44317.1 - 4.3e-07 29.7 0.5 6.7e-07 29.1 0.1 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ44317.1 - 8.8e-07 28.8 0.3 8.8e-07 28.8 0.3 1.4 2 0 0 2 2 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CDJ44317.1 - 5.8e-05 23.3 4.3 0.00037 20.7 3.2 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 CDJ44317.1 - 0.00012 21.6 2.2 0.00012 21.6 1.3 1.5 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CDJ44317.1 - 0.00034 20.7 1.4 0.00089 19.4 1.4 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 CDJ44317.1 - 0.00039 20.5 0.2 0.0018 18.4 0.1 2.0 2 1 0 2 2 2 1 RING-variant domain Prok-RING_4 PF14447.6 CDJ44317.1 - 0.0011 18.8 4.1 0.0077 16.1 3.0 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CDJ44317.1 - 0.0013 18.5 0.1 0.0022 17.8 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 CDJ44317.1 - 0.0075 16.7 0.6 0.009 16.4 0.6 1.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-ANAPC11 PF12861.7 CDJ44317.1 - 0.021 14.8 0.9 0.035 14.1 0.9 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CDJ44317.1 - 0.084 13.0 2.7 0.36 11.0 1.9 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING WD40 PF00400.32 CDJ44318.1 - 2.9e-05 24.7 0.1 0.0095 16.8 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ44318.1 - 0.0001 22.5 0.0 0.0004 20.6 0.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain SR-25 PF10500.9 CDJ44319.1 - 0.0058 16.3 6.8 0.0058 16.3 6.8 3.0 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein LAX PF15681.5 CDJ44321.1 - 0.3 9.9 0.8 0.39 9.5 0.8 1.1 1 0 0 1 1 1 0 Lymphocyte activation family X Metallophos PF00149.28 CDJ44322.1 - 5.4e-33 115.2 0.0 7.5e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Helicase_RecD PF05127.14 CDJ44324.1 - 1.2e-57 194.6 0.0 2e-57 193.9 0.0 1.3 1 1 0 1 1 1 1 Helicase AAA_30 PF13604.6 CDJ44324.1 - 2.4e-07 30.7 0.5 0.00019 21.2 0.6 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDJ44324.1 - 6.8e-05 23.2 0.0 0.00012 22.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ44324.1 - 0.0079 16.5 0.2 0.35 11.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 CDJ44324.1 - 0.09 12.5 0.4 0.34 10.7 0.4 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase Aldo_ket_red PF00248.21 CDJ44326.1 - 4.8e-07 29.3 0.0 1e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Ribosomal_60s PF00428.19 CDJ44326.1 - 8.1 7.1 10.3 80 3.9 8.9 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein RPN7 PF10602.9 CDJ44327.1 - 0.032 14.0 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_16 PF13432.6 CDJ44327.1 - 0.04 14.6 0.8 0.04 14.6 0.8 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ44327.1 - 0.24 11.9 7.1 0.63 10.6 1.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ44327.1 - 6.2 7.9 6.9 24 6.1 0.2 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Syntaxin PF00804.25 CDJ44328.1 - 9.7e-13 48.2 0.2 9.7e-13 48.2 0.2 1.7 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 CDJ44328.1 - 3.6e-10 39.7 1.4 7.7e-10 38.6 1.4 1.6 1 0 0 1 1 1 1 SNARE domain Laminin_II PF06009.12 CDJ44328.1 - 0.012 15.7 1.5 0.016 15.2 1.5 1.3 1 0 0 1 1 1 0 Laminin Domain II Fusion_gly PF00523.18 CDJ44328.1 - 0.014 13.7 0.6 0.023 13.0 0.4 1.3 1 1 0 1 1 1 0 Fusion glycoprotein F0 DUF846 PF05832.12 CDJ44328.1 - 0.014 15.4 0.1 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) MCPsignal PF00015.21 CDJ44328.1 - 0.016 15.0 1.2 0.018 14.9 0.8 1.3 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4577 PF15145.6 CDJ44328.1 - 0.026 14.6 0.2 0.059 13.4 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) Med2 PF11214.8 CDJ44328.1 - 0.036 14.2 0.8 0.048 13.8 0.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 2 MCU PF04678.13 CDJ44328.1 - 0.041 14.0 1.4 0.05 13.7 1.4 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF2207 PF09972.9 CDJ44328.1 - 0.06 12.1 0.2 0.059 12.1 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CRA PF06589.11 CDJ44328.1 - 0.062 13.4 0.1 0.069 13.3 0.1 1.3 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF16 PF01519.16 CDJ44328.1 - 0.088 13.3 2.4 0.11 13.0 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 VIT1 PF01988.19 CDJ44328.1 - 0.097 12.5 0.4 0.12 12.2 0.4 1.1 1 0 0 1 1 1 0 VIT family T2SSF PF00482.23 CDJ44328.1 - 0.14 12.1 6.1 0.83 9.6 6.1 2.0 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F BLOC1_2 PF10046.9 CDJ44328.1 - 0.19 12.1 3.9 0.42 10.9 0.1 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Synaptobrevin PF00957.21 CDJ44328.1 - 2.4 8.0 7.3 4.5 7.1 5.7 2.1 1 1 1 2 2 2 0 Synaptobrevin DEAD PF00270.29 CDJ44329.1 - 2.4e-10 40.4 0.4 2.4e-10 40.4 0.4 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase SseC PF04888.12 CDJ44329.1 - 0.0002 21.1 7.0 0.00021 21.0 7.0 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Pex14_N PF04695.13 CDJ44329.1 - 0.0075 16.9 6.8 0.0099 16.5 6.8 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region ResIII PF04851.15 CDJ44329.1 - 0.028 14.4 4.7 0.12 12.4 4.5 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit LCIB_C_CA PF18599.1 CDJ44329.1 - 0.04 13.2 4.3 0.052 12.8 4.3 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Presenilin PF01080.17 CDJ44329.1 - 0.049 12.4 1.6 0.043 12.6 1.6 1.1 1 0 0 1 1 1 0 Presenilin Neuregulin PF02158.15 CDJ44329.1 - 0.12 11.7 4.5 0.14 11.5 4.5 1.1 1 0 0 1 1 1 0 Neuregulin intracellular region MMR1 PF08505.10 CDJ44329.1 - 0.6 10.4 8.1 0.71 10.1 8.1 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein UPF0560 PF10577.9 CDJ44329.1 - 0.94 7.9 12.0 1.1 7.7 12.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 OmpH PF03938.14 CDJ44329.1 - 9.8 6.5 28.1 0.63 10.4 22.6 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2722 PF10846.8 CDJ44330.1 - 1.2e-05 24.5 6.9 1.2e-05 24.4 6.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ44330.1 - 0.038 13.6 21.0 0.046 13.3 21.0 1.1 1 0 0 1 1 1 0 Spt20 family DUF4407 PF14362.6 CDJ44330.1 - 4.4 6.6 9.1 8 5.7 7.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SNF2_N PF00176.23 CDJ44331.1 - 5.5e-30 104.3 0.0 1.2e-29 103.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ44331.1 - 1.2e-10 41.7 0.0 4.4e-10 39.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ44331.1 - 4.8e-08 33.2 0.4 9e-07 29.0 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CDJ44331.1 - 0.0012 18.1 0.0 0.0012 18.1 0.0 2.5 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase SAM_3 PF18016.1 CDJ44332.1 - 0.081 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TIP49_C PF17856.1 CDJ44333.1 - 3.1e-23 81.7 0.5 4.4e-23 81.2 0.5 1.2 1 0 0 1 1 1 1 TIP49 AAA-lid domain TIP49 PF06068.13 CDJ44333.1 - 5.8e-15 55.4 0.3 2.2e-14 53.4 0.0 1.9 1 1 1 2 2 2 1 TIP49 P-loop domain DUF2722 PF10846.8 CDJ44334.1 - 5.9e-05 22.2 4.0 5.9e-05 22.2 4.0 8.2 6 3 1 7 7 7 1 Protein of unknown function (DUF2722) MAT1 PF06391.13 CDJ44335.1 - 1.2 8.9 15.3 1.6 8.5 15.3 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 UIM PF02809.20 CDJ44336.1 - 0.0088 15.9 1.1 0.0088 15.9 1.1 2.1 2 0 0 2 2 2 1 Ubiquitin interaction motif Cyt-b5 PF00173.28 CDJ44337.1 - 1.1e-09 38.3 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2264 PF10022.9 CDJ44337.1 - 0.096 11.8 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Glyco_transf_34 PF05637.12 CDJ44339.1 - 0.035 13.8 1.4 0.05 13.3 1.4 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family ADK PF00406.22 CDJ44339.1 - 0.54 10.4 6.5 1.8 8.6 5.8 2.2 1 1 1 2 2 2 0 Adenylate kinase Allexi_40kDa PF05549.11 CDJ44339.1 - 3.9 6.9 9.1 3.7 7.0 8.3 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein FAA_hydrolase_N PF09298.11 CDJ44339.1 - 4.7 7.4 10.7 24 5.2 10.6 2.1 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal LMBR1 PF04791.16 CDJ44339.1 - 5.4 5.8 8.9 5.9 5.7 8.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FUSC PF04632.12 CDJ44339.1 - 6.1 5.3 15.4 7.6 4.9 15.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_S46 PF10459.9 CDJ44339.1 - 9.2 4.8 16.4 10 4.6 16.4 1.0 1 0 0 1 1 1 0 Peptidase S46 TIP49 PF06068.13 CDJ44341.1 - 1.2e-64 218.7 0.1 1.3e-64 218.6 0.1 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain Paf1 PF03985.13 CDJ44342.1 - 1.1 8.2 3.8 2.5 7.0 3.8 1.6 1 0 0 1 1 1 0 Paf1 tRNA-synt_2b PF00587.25 CDJ44343.1 - 4.1e-34 118.1 0.1 7.9e-34 117.2 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CDJ44343.1 - 4.4e-20 71.9 1.6 4.4e-20 71.9 1.6 2.4 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain TCTP PF00838.17 CDJ44344.1 - 9.2e-54 182.2 1.8 1e-53 182.1 1.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein URO-D PF01208.17 CDJ44344.1 - 0.08 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Myosin_head PF00063.21 CDJ44348.1 - 1.1e-27 96.6 0.1 8.3e-15 54.0 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) Zeta_toxin PF06414.12 CDJ44348.1 - 0.00069 18.9 0.3 0.086 12.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 CDJ44348.1 - 0.029 14.6 0.0 0.072 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ44348.1 - 0.068 13.6 0.5 0.38 11.1 0.3 2.2 1 1 1 2 2 2 0 AAA ATPase domain Myosin_head PF00063.21 CDJ44350.1 - 2.1e-43 148.5 0.5 2.4e-26 92.2 0.0 2.3 2 0 0 2 2 2 2 Myosin head (motor domain) Coatomer_g_Cpla PF16381.5 CDJ44351.1 - 2.8e-14 53.2 0.0 6.1e-14 52.1 0.0 1.6 1 1 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform Alpha_adaptin_C PF02296.16 CDJ44351.1 - 0.25 11.5 0.0 9.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain DnaJ PF00226.31 CDJ44352.1 - 1.5e-15 57.0 1.0 2e-15 56.7 1.0 1.1 1 0 0 1 1 1 1 DnaJ domain WBP-1 PF11669.8 CDJ44353.1 - 0.015 16.0 0.1 2.3 8.9 0.0 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 DUF3522 PF12036.8 CDJ44353.1 - 0.074 13.3 0.5 0.15 12.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) DUF1180 PF06679.12 CDJ44353.1 - 0.59 10.5 8.9 0.71 10.3 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TFIIA PF03153.13 CDJ44353.1 - 4.1 7.3 7.5 5.9 6.8 7.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cpn60_TCP1 PF00118.24 CDJ44354.1 - 2.2e-20 72.8 0.4 2.3e-20 72.7 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SMC_hinge PF06470.13 CDJ44356.1 - 0.00063 20.0 0.1 0.00063 20.0 0.1 2.4 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain CcdB PF01845.17 CDJ44356.1 - 0.088 13.0 2.2 0.27 11.5 2.1 1.9 1 1 0 1 1 1 0 CcdB protein DUF3446 PF11928.8 CDJ44356.1 - 0.66 10.3 13.8 0.82 10.0 12.6 1.8 2 0 0 2 2 2 0 Early growth response N-terminal domain Pyr_redox_2 PF07992.14 CDJ44360.1 - 4.4e-58 196.8 0.0 5.6e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ44360.1 - 3.8e-20 72.2 0.7 1.6e-15 57.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ44360.1 - 1.6e-14 53.9 0.7 7.5e-12 45.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ44360.1 - 3.6e-07 29.9 0.0 8.6e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_dim PF02852.22 CDJ44360.1 - 5.9e-07 29.7 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GIDA PF01134.22 CDJ44360.1 - 1.4e-05 24.3 0.1 0.00049 19.3 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CDJ44360.1 - 0.0012 18.1 0.6 0.75 9.0 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CDJ44360.1 - 0.0015 18.0 0.3 0.53 9.6 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 CDJ44360.1 - 0.0036 16.1 0.6 0.049 12.3 0.6 2.3 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.6 CDJ44360.1 - 0.0038 16.4 0.0 0.006 15.8 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CDJ44360.1 - 0.0039 17.4 3.3 0.0048 17.1 0.5 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 CDJ44360.1 - 0.0047 17.3 0.2 4.5 7.8 0.2 2.9 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 CDJ44360.1 - 0.0066 15.6 4.4 0.096 11.7 1.8 2.8 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 CDJ44360.1 - 0.014 14.7 0.7 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 CDJ44360.1 - 0.015 14.5 0.2 0.041 13.1 0.1 1.8 2 0 0 2 2 2 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 CDJ44360.1 - 0.023 14.7 0.5 4.4 7.3 0.0 2.7 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RepB_primase PF16793.5 CDJ44360.1 - 0.024 14.8 0.1 0.043 13.9 0.1 1.3 1 0 0 1 1 1 0 RepB DNA-primase from phage plasmid 3HCDH_N PF02737.18 CDJ44360.1 - 0.073 13.0 3.8 0.95 9.3 0.0 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 CDJ44360.1 - 0.099 12.2 7.0 0.18 11.3 2.7 2.7 3 1 0 3 3 3 0 FAD dependent oxidoreductase Pertactin PF03212.14 CDJ44360.1 - 0.17 11.8 0.1 4.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Pertactin F420_oxidored PF03807.17 CDJ44360.1 - 0.69 10.5 4.1 91 3.7 0.0 3.5 3 1 1 4 4 3 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 CDJ44360.1 - 1.4 8.3 5.5 5.8 6.3 1.1 2.9 3 1 0 3 3 3 0 short chain dehydrogenase DUF2722 PF10846.8 CDJ44361.1 - 2.2e-06 26.9 1.9 2.2e-06 26.9 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) FYTT PF07078.11 CDJ44361.1 - 2.9e-05 23.6 4.2 4e-05 23.1 4.2 1.2 1 0 0 1 1 1 1 Forty-two-three protein RRM_1 PF00076.22 CDJ44361.1 - 3.1e-05 23.7 0.0 5.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cnd2 PF05786.14 CDJ44361.1 - 0.00064 18.5 0.6 0.00069 18.4 0.6 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF4770 PF15994.5 CDJ44361.1 - 0.0067 16.7 7.9 0.0095 16.2 7.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4770) ANAPC_CDC26 PF10471.9 CDJ44361.1 - 0.0092 16.8 16.7 0.0092 16.8 16.7 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex APC subunit CDC26 DDHD PF02862.17 CDJ44361.1 - 0.022 14.9 0.2 0.022 14.9 0.2 1.1 1 0 0 1 1 1 0 DDHD domain Spt20 PF12090.8 CDJ44361.1 - 0.16 11.6 21.6 0.2 11.2 21.6 1.1 1 0 0 1 1 1 0 Spt20 family DUF702 PF05142.12 CDJ44361.1 - 0.3 11.6 7.0 0.44 11.0 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Presenilin PF01080.17 CDJ44361.1 - 0.4 9.4 5.3 0.48 9.1 5.3 1.1 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 CDJ44361.1 - 0.49 10.1 4.1 0.68 9.7 4.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SRRM_C PF15230.6 CDJ44361.1 - 0.58 10.8 5.9 1 10.0 5.9 1.3 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus DUF4834 PF16118.5 CDJ44361.1 - 0.66 11.0 7.7 1.1 10.2 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF1764 PF08576.10 CDJ44361.1 - 1.5 9.8 8.6 2.2 9.2 8.6 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) TERB2 PF15101.6 CDJ44361.1 - 2.3 8.2 9.0 2.9 7.9 9.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Hydin_ADK PF17213.3 CDJ44361.1 - 3 8.1 7.3 4.2 7.6 7.3 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Androgen_recep PF02166.16 CDJ44361.1 - 3.1 6.5 19.2 4.3 6.1 19.2 1.1 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 CDJ44361.1 - 3.2 7.6 20.1 4.1 7.3 20.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 CDJ44361.1 - 3.7 5.7 7.6 4.4 5.5 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 CDJ44361.1 - 4 6.5 9.6 5 6.1 9.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PKI PF02827.16 CDJ44361.1 - 6.9 7.0 8.9 11 6.3 8.9 1.4 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Ndc1_Nup PF09531.10 CDJ44361.1 - 9.8 4.7 6.4 13 4.3 6.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PTPRCAP PF15713.5 CDJ44362.1 - 0.0059 16.9 13.3 0.0074 16.6 13.3 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated TFIIA PF03153.13 CDJ44362.1 - 0.21 11.6 34.7 0.21 11.5 34.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ44362.1 - 0.29 9.8 14.4 0.28 9.9 14.4 1.0 1 0 0 1 1 1 0 Presenilin Trypan_PARP PF05887.11 CDJ44362.1 - 0.37 10.8 4.3 0.58 10.1 4.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Zip PF02535.22 CDJ44362.1 - 0.57 9.3 5.6 0.53 9.4 5.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 CDJ44362.1 - 0.94 8.4 10.5 0.94 8.4 10.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 CDJ44362.1 - 2 7.1 9.9 2 7.1 9.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Otopetrin PF03189.13 CDJ44362.1 - 2.7 6.7 4.5 3.5 6.3 4.5 1.1 1 0 0 1 1 1 0 Otopetrin DUF913 PF06025.12 CDJ44362.1 - 3.3 6.6 6.7 3.5 6.5 6.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ndc1_Nup PF09531.10 CDJ44362.1 - 6.8 5.2 11.3 6.8 5.3 11.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ephrin_rec_like PF07699.13 CDJ44363.1 - 3.5e-07 29.9 50.5 0.0014 18.3 5.0 6.5 3 3 1 4 4 4 3 Putative ephrin-receptor like FLYWCH PF04500.16 CDJ44363.1 - 2.8 8.1 5.8 0.6 10.3 1.8 2.0 2 0 0 2 2 2 0 FLYWCH zinc finger domain tRNA-synt_His PF13393.6 CDJ44364.1 - 1.1e-24 87.3 0.8 1.4e-24 87.0 0.8 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CDJ44364.1 - 3.9e-08 33.3 0.0 8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain PALP PF00291.25 CDJ44364.1 - 0.059 12.8 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme YL1 PF05764.13 CDJ44365.1 - 2e-05 24.9 24.8 2.2e-05 24.7 24.8 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 CDJ44365.1 - 6.2e-05 21.5 25.3 6.3e-05 21.4 25.3 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 CDJ44365.1 - 0.00028 20.4 26.9 0.00031 20.3 26.9 1.1 1 0 0 1 1 1 1 SDA1 Merozoite_SPAM PF07133.11 CDJ44365.1 - 0.00041 20.4 31.4 0.00052 20.1 31.4 1.2 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) DNA_pol_phi PF04931.13 CDJ44365.1 - 0.0023 16.1 27.8 0.003 15.7 27.8 1.2 1 0 0 1 1 1 1 DNA polymerase phi CDC45 PF02724.14 CDJ44365.1 - 0.0052 15.2 29.0 0.0065 14.8 29.0 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop53 PF07767.11 CDJ44365.1 - 0.0056 16.1 28.9 0.0081 15.6 28.9 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) GAGA_bind PF06217.12 CDJ44365.1 - 0.01 16.1 7.0 0.012 15.9 7.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Lin-8 PF03353.15 CDJ44365.1 - 0.047 13.3 15.3 0.053 13.1 15.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mpp10 PF04006.12 CDJ44365.1 - 0.066 11.7 29.1 0.08 11.4 29.1 1.1 1 0 0 1 1 1 0 Mpp10 protein TFIIF_alpha PF05793.12 CDJ44365.1 - 0.073 11.7 31.3 0.083 11.5 31.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SLC12 PF03522.15 CDJ44365.1 - 0.1 11.6 11.5 0.12 11.3 11.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PTPRCAP PF15713.5 CDJ44365.1 - 0.11 12.8 32.7 0.17 12.2 32.7 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PIP5K PF01504.18 CDJ44365.1 - 0.13 11.5 9.2 0.3 10.3 9.2 1.6 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase RR_TM4-6 PF06459.12 CDJ44365.1 - 0.17 11.7 22.0 0.23 11.3 22.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ44365.1 - 0.23 10.2 18.6 0.28 9.9 18.6 1.1 1 0 0 1 1 1 0 Presenilin TRAP_alpha PF03896.16 CDJ44365.1 - 0.35 10.1 19.7 0.95 8.6 19.7 1.7 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cwf_Cwc_15 PF04889.12 CDJ44365.1 - 0.47 10.1 33.9 0.64 9.7 33.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Neur_chan_memb PF02932.16 CDJ44365.1 - 0.68 9.9 7.2 0.75 9.8 7.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.9 CDJ44365.1 - 0.76 8.6 15.0 0.82 8.5 15.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2828 PF11443.8 CDJ44365.1 - 1.2 7.1 9.3 1.4 6.9 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2151 PF10221.9 CDJ44365.1 - 1.2 7.6 11.7 1.4 7.4 11.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Raftlin PF15250.6 CDJ44365.1 - 1.4 7.6 14.6 1.5 7.4 14.6 1.0 1 0 0 1 1 1 0 Raftlin TipE PF16972.5 CDJ44365.1 - 1.6 7.8 7.6 1.9 7.6 7.6 1.0 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE TP53IP5 PF15331.6 CDJ44365.1 - 1.9 8.6 10.1 2.3 8.3 10.1 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 CCSAP PF15748.5 CDJ44365.1 - 2.1 8.5 20.7 2.5 8.2 20.7 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Glypican PF01153.19 CDJ44365.1 - 2.1 7.1 14.2 2.6 6.8 14.2 1.1 1 0 0 1 1 1 0 Glypican Suf PF05843.14 CDJ44365.1 - 2.3 8.1 9.8 2.6 8.0 9.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LAP1C PF05609.12 CDJ44365.1 - 2.3 7.2 16.8 2.7 7.0 16.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) eIF-3c_N PF05470.12 CDJ44365.1 - 3 6.0 16.6 3.6 5.8 16.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Rrn6 PF10214.9 CDJ44365.1 - 3.3 6.1 12.8 3.6 6.0 12.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CCDC106 PF15794.5 CDJ44365.1 - 3.3 7.4 14.4 4.4 7.0 14.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Hid1 PF12722.7 CDJ44365.1 - 4.2 5.4 16.7 4.9 5.1 16.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 CDJ44365.1 - 4.9 5.8 16.8 6.4 5.4 16.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RP-C_C PF11800.8 CDJ44365.1 - 5.3 7.1 11.3 6.8 6.7 11.3 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region GREB1 PF15782.5 CDJ44365.1 - 6.6 3.7 13.3 7.8 3.5 13.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S64 PF08192.11 CDJ44365.1 - 7.4 4.9 12.5 8.3 4.8 12.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 IFT57 PF10498.9 CDJ44365.1 - 8 5.3 21.0 10 5.0 21.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RNA_polI_A34 PF08208.11 CDJ44365.1 - 9.2 6.3 29.3 13 5.8 29.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 EF-hand_1 PF00036.32 CDJ44366.1 - 1.5e-25 86.8 0.0 3.6e-07 29.3 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ44366.1 - 1.9e-22 79.5 0.0 4.5e-11 43.0 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ44366.1 - 5.4e-22 75.8 0.0 1.3e-05 24.7 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDJ44366.1 - 6.4e-20 70.7 0.6 5.2e-06 26.2 0.1 4.4 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CDJ44366.1 - 8.4e-19 66.2 0.4 4e-07 29.2 0.0 4.1 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 CDJ44366.1 - 6.8e-08 32.8 0.0 5.4e-05 23.5 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDJ44366.1 - 1.1e-06 28.5 0.0 0.0005 20.0 0.0 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CDJ44366.1 - 0.00035 20.7 1.2 0.011 15.9 0.4 2.4 1 1 1 2 2 2 2 Dockerin type I domain EF-hand_9 PF14658.6 CDJ44366.1 - 0.0019 18.5 0.0 0.23 11.8 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain Smg4_UPF3 PF03467.15 CDJ44366.1 - 0.0058 16.7 0.0 0.0078 16.2 0.0 1.2 1 0 0 1 1 1 1 Smg-4/UPF3 family DUF1194 PF06707.11 CDJ44366.1 - 0.016 14.5 0.1 0.045 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) AAA_lid_9 PF17871.1 CDJ44367.1 - 0.025 14.5 2.6 0.025 14.5 2.6 1.8 1 1 1 2 2 2 0 AAA lid domain DUF3450 PF11932.8 CDJ44367.1 - 0.03 13.6 11.9 0.037 13.3 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1515 PF07439.11 CDJ44367.1 - 0.12 12.4 2.2 0.14 12.2 1.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Herpes_UL6 PF01763.16 CDJ44367.1 - 0.14 10.6 3.9 0.16 10.5 3.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF1664 PF07889.12 CDJ44367.1 - 0.17 11.9 3.9 0.32 11.0 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ERM PF00769.19 CDJ44367.1 - 0.47 10.2 16.8 0.55 10.0 16.8 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 CDJ44367.1 - 0.5 10.4 19.6 0.28 11.3 13.9 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Endonuc_Holl PF10107.9 CDJ44367.1 - 0.79 9.6 4.1 0.92 9.3 4.1 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase UPF0242 PF06785.11 CDJ44367.1 - 1.3 9.1 12.8 1.6 8.8 12.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 CDJ44367.1 - 1.7 6.5 5.0 1.7 6.4 5.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 CDJ44367.1 - 1.8 9.1 20.4 2.2 8.8 19.5 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 CDJ44367.1 - 3 6.3 6.9 3.5 6.1 6.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-H PF05837.12 CDJ44367.1 - 5 7.6 14.2 6.8 7.1 13.3 1.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) YabA PF06156.13 CDJ44367.1 - 6.4 7.5 8.6 20 5.9 8.5 1.8 1 1 0 1 1 1 0 Initiation control protein YabA FUSC PF04632.12 CDJ44367.1 - 7.5 4.9 11.0 7.9 4.9 11.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family CarboxypepD_reg PF13620.6 CDJ44368.1 - 0.0004 20.6 0.1 0.0026 18.0 0.6 2.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain SUIM_assoc PF16619.5 CDJ44368.1 - 0.28 11.3 5.8 0.57 10.3 0.7 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DDHD PF02862.17 CDJ44369.1 - 0.0051 17.0 2.5 0.0054 16.9 2.5 1.1 1 0 0 1 1 1 1 DDHD domain DUF3295 PF11702.8 CDJ44369.1 - 0.013 14.9 11.9 0.015 14.7 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Hepcidin PF06446.12 CDJ44369.1 - 0.041 14.3 5.3 0.041 14.3 5.3 2.4 1 1 1 2 2 2 0 Hepcidin Zip PF02535.22 CDJ44369.1 - 0.068 12.4 4.2 0.08 12.1 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF778 PF05608.12 CDJ44369.1 - 1.3 9.4 6.4 1.5 9.1 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF778) TFIIA PF03153.13 CDJ44369.1 - 2 8.3 32.5 2.5 8.0 32.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ44369.1 - 2.5 7.5 12.5 3.3 7.1 12.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PAT1 PF09770.9 CDJ44369.1 - 4.2 5.5 22.3 5 5.3 22.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rrn6 PF10214.9 CDJ44369.1 - 4.3 5.7 21.7 5 5.5 21.7 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SLC12 PF03522.15 CDJ44369.1 - 4.7 6.1 14.2 5.7 5.8 14.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CPSF100_C PF13299.6 CDJ44369.1 - 7.2 6.8 14.2 9.7 6.3 14.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4746 PF15928.5 CDJ44369.1 - 7.9 5.8 14.7 10 5.5 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 CDJ44369.1 - 8 5.1 20.1 10 4.7 20.1 1.1 1 0 0 1 1 1 0 Presenilin DDRGK PF09756.9 CDJ44369.1 - 8.8 5.9 22.8 12 5.5 22.8 1.1 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.12 CDJ44369.1 - 9.1 6.0 16.7 12 5.7 16.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tristanin_u2 PF16638.5 CDJ44369.1 - 9.3 7.1 16.8 14 6.5 16.8 1.2 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers Ctr PF04145.15 CDJ44369.1 - 9.5 6.8 5.7 13 6.3 5.7 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Lactamase_B_4 PF13691.6 CDJ44370.1 - 7.3e-06 25.6 0.0 1.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease SLR1-BP PF07333.12 CDJ44370.1 - 0.091 13.2 1.8 0.18 12.3 1.8 1.4 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) CAF1 PF04857.20 CDJ44371.1 - 3e-17 62.8 0.2 3.8e-17 62.5 0.2 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease ComGF PF15980.5 CDJ44371.1 - 0.037 14.4 3.4 0.048 14.0 3.4 1.1 1 0 0 1 1 1 0 Putative Competence protein ComGF DUF2722 PF10846.8 CDJ44371.1 - 0.26 10.2 3.1 0.22 10.4 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) U6-snRNA_bdg PF10596.9 CDJ44373.1 - 5e-24 85.1 0.4 8.6e-24 84.3 0.4 1.4 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PhetRS_B1 PF18262.1 CDJ44373.1 - 0.0036 17.5 0.0 0.0044 17.2 0.0 1.1 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain Regnase_1_C PF18561.1 CDJ44373.1 - 0.077 12.7 0.1 0.7 9.7 0.0 2.2 1 1 1 2 2 2 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain Med3 PF11593.8 CDJ44374.1 - 0.003 16.8 7.9 0.0034 16.6 7.9 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DUF775 PF05603.12 CDJ44374.1 - 0.017 14.6 0.4 0.017 14.6 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF775) SUIM_assoc PF16619.5 CDJ44374.1 - 0.024 14.7 1.8 0.024 14.7 1.8 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TrbI PF03743.14 CDJ44374.1 - 2.1 8.2 7.8 1.8 8.4 3.7 2.2 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein DUF1180 PF06679.12 CDJ44374.1 - 3.8 7.9 9.3 1.4 9.3 5.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) S6PP_C PF08472.10 CDJ44375.1 - 0.088 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal SR-25 PF10500.9 CDJ44375.1 - 0.39 10.3 10.4 0.49 10.0 10.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 CDJ44375.1 - 0.96 7.8 3.2 0.98 7.8 3.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Nkap_C PF06047.11 CDJ44376.1 - 3.6e-26 91.2 0.2 4.7e-26 90.9 0.2 1.1 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain FGF-BP1 PF06473.12 CDJ44377.1 - 0.45 10.3 6.3 0.58 10.0 6.3 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF2052 PF09747.9 CDJ44377.1 - 0.91 9.6 5.8 1.1 9.4 5.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SspB PF04386.13 CDJ44377.1 - 1.6 8.6 5.2 2.1 8.2 5.2 1.2 1 0 0 1 1 1 0 Stringent starvation protein B PGA2 PF07543.12 CDJ44377.1 - 2 8.4 7.2 2.8 7.9 7.2 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Spt20 PF12090.8 CDJ44377.1 - 2.3 7.7 5.7 2.7 7.6 5.7 1.2 1 0 0 1 1 1 0 Spt20 family DUF3138 PF11336.8 CDJ44377.1 - 4.1 5.9 8.3 4.2 5.9 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4554 PF15091.6 CDJ44377.1 - 9.6 5.0 6.9 11 4.7 6.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) SR-25 PF10500.9 CDJ44379.1 - 0.91 9.1 11.9 1.2 8.7 11.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Androgen_recep PF02166.16 CDJ44380.1 - 0.0002 20.4 2.8 0.0002 20.4 2.8 3.3 2 1 1 3 3 3 1 Androgen receptor Spt20 PF12090.8 CDJ44380.1 - 0.84 9.2 10.9 0.046 13.3 5.6 1.5 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 CDJ44381.1 - 0.00044 20.3 17.6 0.0014 18.6 0.8 2.7 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 EphA2_TM PF14575.6 CDJ44381.1 - 0.0087 16.9 0.5 0.14 13.0 0.0 2.4 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain FGF-BP1 PF06473.12 CDJ44381.1 - 0.0093 15.8 0.2 0.0093 15.8 0.2 2.8 3 0 0 3 3 3 1 FGF binding protein 1 (FGF-BP1) Polysacc_deac_2 PF04748.13 CDJ44381.1 - 0.0099 15.1 1.5 0.0099 15.1 1.5 1.8 2 0 0 2 2 2 1 Divergent polysaccharide deacetylase DUF4083 PF13314.6 CDJ44381.1 - 0.037 14.0 0.2 0.07 13.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF4191 PF13829.6 CDJ44381.1 - 0.038 13.3 0.1 0.059 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2140 PF09911.9 CDJ44381.1 - 0.067 12.7 1.6 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) GRP PF07172.11 CDJ44381.1 - 0.11 13.2 0.6 1.1 10.0 0.0 2.3 2 0 0 2 2 2 0 Glycine rich protein family DUF4064 PF13273.6 CDJ44381.1 - 0.12 12.6 0.9 2 8.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4834 PF16118.5 CDJ44381.1 - 0.51 11.3 9.0 0.99 10.4 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) DUF2973 PF11189.8 CDJ44381.1 - 0.55 10.4 3.4 6.1 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) RIC3 PF15361.6 CDJ44381.1 - 0.63 10.4 0.1 0.63 10.4 0.1 2.8 3 1 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 TFIIA PF03153.13 CDJ44381.1 - 4.4 7.2 32.4 9.3 6.1 32.4 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4131 PF13567.6 CDJ44381.1 - 4.7 6.8 11.8 7.5 6.2 6.0 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4131) ABC2_membrane_2 PF12679.7 CDJ44381.1 - 6.2 6.0 9.3 0.06 12.6 0.3 2.2 2 1 0 3 3 3 0 ABC-2 family transporter protein DUF2722 PF10846.8 CDJ44382.1 - 6.8e-05 22.0 0.1 6.8e-05 22.0 0.1 10.0 9 2 1 10 10 10 5 Protein of unknown function (DUF2722) AAA_6 PF12774.7 CDJ44383.1 - 9.4e-09 34.7 0.2 1.4e-08 34.1 0.2 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ44383.1 - 4.5e-08 32.6 0.0 6.9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 MCM_OB PF17207.3 CDJ44384.1 - 1.6e-24 86.2 0.2 2.3e-24 85.6 0.2 1.2 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 CDJ44384.1 - 8.2e-06 26.4 0.0 1.3e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 MCM N-terminal domain SUIM_assoc PF16619.5 CDJ44386.1 - 0.013 15.6 2.0 0.017 15.1 2.0 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Glyco_transf_20 PF00982.21 CDJ44387.1 - 8.7e-90 301.7 0.0 1.8e-89 300.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 20 SUIM_assoc PF16619.5 CDJ44387.1 - 0.011 15.7 22.5 0.086 12.9 0.1 3.9 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Bacteriocin_IIc PF10439.9 CDJ44387.1 - 0.014 15.5 4.4 0.04 14.0 4.4 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide TFIIA PF03153.13 CDJ44387.1 - 0.085 12.8 22.6 0.32 10.9 14.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 CDJ44387.1 - 1.6 7.8 22.6 3.3 6.8 22.6 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein PAN_1 PF00024.26 CDJ44388.1 - 3.7e-27 94.1 28.3 4.4e-08 33.0 2.2 4.3 4 0 0 4 4 4 4 PAN domain PAN_4 PF14295.6 CDJ44388.1 - 3.9e-18 65.1 25.9 6e-06 26.1 0.6 4.4 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.11 CDJ44388.1 - 0.00037 20.6 25.7 0.12 12.5 1.2 4.5 4 0 0 4 4 4 3 PAN-like domain MANEC PF07502.14 CDJ44388.1 - 0.019 15.2 26.8 0.074 13.3 1.4 4.5 4 0 0 4 4 4 0 MANEC domain PAN_3 PF08277.12 CDJ44388.1 - 0.078 12.8 0.7 0.078 12.8 0.7 4.3 4 0 0 4 4 4 0 PAN-like domain LCIB_C_CA PF18599.1 CDJ44389.1 - 0.42 9.9 2.7 0.49 9.6 2.7 1.0 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases CYSTM PF12734.7 CDJ44392.1 - 0.058 13.7 2.4 0.1 12.9 2.4 1.3 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Macoilin PF09726.9 CDJ44394.1 - 3.2 6.2 12.4 4 5.9 12.4 1.2 1 0 0 1 1 1 0 Macoilin family SUIM_assoc PF16619.5 CDJ44395.1 - 0.016 15.3 2.9 0.022 14.8 2.9 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Cytochrom_B_N_2 PF13631.6 CDJ44395.1 - 0.067 13.2 0.1 0.097 12.7 0.1 1.4 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB RNase_II_C_S1 PF18614.1 CDJ44395.1 - 0.068 13.1 1.2 0.69 9.9 0.0 2.3 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain Memo PF01875.17 CDJ44396.1 - 1.2e-12 47.6 0.0 1.3e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein EVI2A PF05399.11 CDJ44397.1 - 0.29 10.7 4.5 0.43 10.1 4.5 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Med13_C PF06333.12 CDJ44397.1 - 1.1 8.5 5.6 1.6 8.0 5.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain RIFIN PF02009.16 CDJ44397.1 - 2.4 8.0 3.1 3.5 7.4 3.1 1.1 1 0 0 1 1 1 0 Rifin DUF4666 PF15697.5 CDJ44398.1 - 0.0088 16.7 0.2 0.013 16.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4666) Spt20 PF12090.8 CDJ44398.1 - 0.012 15.3 11.9 0.016 14.9 11.9 1.1 1 0 0 1 1 1 0 Spt20 family DDHD PF02862.17 CDJ44398.1 - 0.04 14.1 0.8 0.043 14.0 0.8 1.2 1 0 0 1 1 1 0 DDHD domain FAM176 PF14851.6 CDJ44398.1 - 0.074 12.7 4.4 0.12 12.0 4.4 1.2 1 0 0 1 1 1 0 FAM176 family Presenilin PF01080.17 CDJ44398.1 - 0.076 11.8 2.5 0.076 11.8 2.5 1.1 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 CDJ44398.1 - 0.082 11.8 9.1 0.1 11.5 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CPSF100_C PF13299.6 CDJ44398.1 - 0.11 12.7 5.1 0.19 11.9 5.1 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TERB2 PF15101.6 CDJ44398.1 - 0.15 12.1 8.1 0.21 11.6 8.1 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NARP1 PF12569.8 CDJ44398.1 - 0.21 10.4 5.5 0.28 10.1 5.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Hid1 PF12722.7 CDJ44398.1 - 0.23 9.6 1.2 0.25 9.4 1.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ecl1 PF12855.7 CDJ44398.1 - 0.27 12.4 7.7 0.043 15.0 4.2 1.4 2 0 0 2 2 1 0 ECL1/2/3 zinc binding proteins DUF3464 PF11947.8 CDJ44398.1 - 0.33 10.7 5.6 0.67 9.7 5.6 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF3995 PF13160.6 CDJ44398.1 - 0.36 11.2 6.1 1.2 9.5 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Neur_chan_memb PF02932.16 CDJ44398.1 - 0.4 10.7 2.2 0.44 10.6 2.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4820 PF16091.5 CDJ44398.1 - 0.45 9.9 5.2 0.84 9.0 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Ndc1_Nup PF09531.10 CDJ44398.1 - 0.57 8.8 4.6 0.65 8.6 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NINJA_B PF16136.5 CDJ44398.1 - 0.65 10.4 8.6 0.5 10.8 7.0 1.7 1 1 1 2 2 2 0 Putative nuclear localisation signal CCDC53 PF10152.9 CDJ44398.1 - 0.77 10.2 16.1 4.9 7.6 0.0 2.2 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Sec62 PF03839.16 CDJ44398.1 - 0.9 9.0 3.4 1.2 8.5 3.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Connexin PF00029.19 CDJ44398.1 - 1.5 8.6 3.1 2 8.1 3.1 1.2 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 CDJ44398.1 - 1.5 7.8 3.0 2 7.3 3.0 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4834 PF16118.5 CDJ44398.1 - 1.8 9.6 6.9 2.8 8.9 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF1631 PF07793.11 CDJ44398.1 - 1.9 6.8 20.4 2.5 6.4 20.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) GREB1 PF15782.5 CDJ44398.1 - 3.6 4.6 5.6 3.6 4.6 5.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3306 PF11748.8 CDJ44398.1 - 5.8 7.8 14.8 2 9.3 9.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Ufd2P_core PF10408.9 CDJ44398.1 - 9 4.8 13.0 12 4.3 13.0 1.0 1 0 0 1 1 1 0 Ubiquitin elongating factor core EIIBC-GUT_N PF03612.14 CDJ44398.1 - 9.7 5.9 6.6 14 5.3 6.6 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Epimerase PF01370.21 CDJ44399.1 - 0.0047 16.4 7.9 3 7.2 0.0 5.5 4 2 1 5 5 5 2 NAD dependent epimerase/dehydratase family YEATS PF03366.16 CDJ44399.1 - 0.008 16.1 17.1 19 5.3 0.1 7.8 6 2 1 8 8 8 2 YEATS family Spt20 PF12090.8 CDJ44402.1 - 0.0049 16.5 5.1 0.0058 16.3 5.1 1.1 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ44402.1 - 0.015 14.3 3.5 0.017 14.1 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ44402.1 - 0.04 13.9 7.7 0.057 13.4 7.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIA PF03153.13 CDJ44403.1 - 0.044 13.8 2.6 0.042 13.8 2.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 CDJ44404.1 - 4e-34 118.2 0.5 4.2e-34 118.1 0.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ44404.1 - 5e-20 71.9 0.3 5.3e-20 71.8 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ44404.1 - 0.00034 20.1 0.3 0.00044 19.7 0.3 1.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ44404.1 - 0.0012 18.8 0.7 0.0038 17.2 0.4 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDJ44404.1 - 0.0019 17.2 0.1 0.0019 17.2 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CDJ44404.1 - 0.0059 16.2 0.0 0.0066 16.0 0.0 1.1 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 CDJ44404.1 - 0.023 14.3 0.4 0.023 14.3 0.4 1.3 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 CDJ44404.1 - 0.029 13.7 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like YukC PF10140.9 CDJ44404.1 - 0.037 12.8 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Sel1 PF08238.12 CDJ44407.1 - 5.3e-05 23.8 2.0 0.045 14.4 0.0 3.6 2 1 0 2 2 2 2 Sel1 repeat TcdB_N PF12918.7 CDJ44408.1 - 0.21 11.9 0.4 0.35 11.2 0.4 1.3 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain RNA_pol_Rpc4 PF05132.14 CDJ44408.1 - 2.5 8.5 9.3 10 6.6 2.2 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Urm1 PF09138.11 CDJ44412.1 - 2.4e-18 66.3 0.0 6.5e-18 64.9 0.0 1.7 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CDJ44412.1 - 0.002 18.7 0.0 0.0031 18.1 0.0 1.4 1 0 0 1 1 1 1 ThiS family Androgen_recep PF02166.16 CDJ44414.1 - 1.2 7.9 8.8 1.2 7.8 8.8 1.0 1 0 0 1 1 1 0 Androgen receptor ABC_membrane PF00664.23 CDJ44415.1 - 4.7e-15 56.0 0.8 4.7e-15 56.0 0.8 1.3 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ44415.1 - 1.9e-12 47.9 0.0 3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ44415.1 - 0.00082 19.3 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ44415.1 - 0.0014 18.3 0.1 0.0031 17.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CDJ44415.1 - 0.0033 17.8 0.1 0.0033 17.8 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ44415.1 - 0.0057 16.6 0.0 0.0095 15.9 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 CDJ44415.1 - 0.013 15.2 0.1 0.013 15.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDJ44415.1 - 0.024 14.9 0.1 0.043 14.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CDJ44415.1 - 0.05 14.1 0.0 0.078 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CDJ44415.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 CDJ44415.1 - 0.2 11.7 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 CDJ44415.1 - 0.23 11.9 0.3 0.45 11.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain BOP1NT PF08145.12 CDJ44416.1 - 1.8e-18 67.4 2.2 1.8e-18 67.4 2.2 1.8 2 0 0 2 2 2 1 BOP1NT (NUC169) domain DUF86 PF01934.17 CDJ44416.1 - 0.0042 17.0 0.2 0.0067 16.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF86 Spt20 PF12090.8 CDJ44416.1 - 0.56 9.8 8.1 0.83 9.2 8.1 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ44416.1 - 2.7 8.1 12.9 7.9 6.6 12.9 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 CDJ44416.1 - 2.9 8.5 15.2 13 6.4 15.2 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein DNA_primase_lrg PF04104.14 CDJ44418.1 - 4.8e-29 101.6 0.0 6.2e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Pkinase PF00069.25 CDJ44419.1 - 1.3e-32 113.3 0.1 1.5e-32 113.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ44419.1 - 2.5e-13 49.9 0.0 2.7e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ44419.1 - 2.1e-07 31.1 0.1 4.4e-06 26.8 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ44419.1 - 0.0001 21.8 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDJ44419.1 - 0.00074 19.2 0.1 0.0009 18.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CDJ44419.1 - 0.0057 15.5 0.1 0.0076 15.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 CDJ44419.1 - 0.011 15.3 0.2 0.014 15.0 0.2 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 CDJ44419.1 - 0.035 13.7 0.1 0.059 13.0 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RHH_4 PF13467.6 CDJ44420.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain Adeno_52K PF03052.15 CDJ44421.1 - 2.2 7.7 9.5 4.9 6.5 5.5 2.1 2 0 0 2 2 2 0 Adenoviral protein L1 52/55-kDa Spt20 PF12090.8 CDJ44422.1 - 2.1 7.9 8.4 2.8 7.5 8.4 1.2 1 0 0 1 1 1 0 Spt20 family Med25_NR-box PF11244.8 CDJ44426.1 - 4.6 7.7 9.0 0.34 11.3 1.4 2.8 2 1 0 3 3 3 0 Mediator complex subunit 25 C-terminal NR box-containing CBM_20 PF00686.19 CDJ44427.1 - 4.9e-18 64.8 0.1 5.9e-18 64.6 0.1 1.1 1 0 0 1 1 1 1 Starch binding domain Peptidase_C8 PF03569.13 CDJ44427.1 - 0.02 14.5 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C8 Peroxin-22 PF12827.7 CDJ44429.1 - 0.0082 16.1 0.0 0.013 15.4 0.0 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family Sporozoite_P67 PF05642.11 CDJ44431.1 - 1.3 7.0 5.2 3.8 5.5 5.2 1.8 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_60s PF00428.19 CDJ44432.1 - 0.18 12.4 5.2 0.2 12.3 5.2 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein GBP PF02263.19 CDJ44433.1 - 1.3e-08 34.5 1.0 2.2e-08 33.7 0.0 1.7 2 0 0 2 2 1 1 Guanylate-binding protein, N-terminal domain DUF2722 PF10846.8 CDJ44433.1 - 0.00092 18.3 8.9 0.00096 18.2 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ44433.1 - 0.0011 19.8 1.3 0.0018 19.2 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) FAM176 PF14851.6 CDJ44433.1 - 0.0029 17.3 0.2 0.0037 16.9 0.2 1.1 1 0 0 1 1 1 1 FAM176 family CPSF100_C PF13299.6 CDJ44433.1 - 0.005 17.0 2.8 0.0067 16.6 2.8 1.2 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 CDJ44433.1 - 0.0052 17.0 0.2 0.0052 17.0 0.2 1.1 1 0 0 1 1 1 1 DDHD domain Dynamin_N PF00350.23 CDJ44433.1 - 0.0062 16.6 1.8 2 8.5 0.0 2.2 2 0 0 2 2 2 1 Dynamin family Androgen_recep PF02166.16 CDJ44433.1 - 0.0094 14.8 10.2 0.011 14.6 10.2 1.2 1 0 0 1 1 1 1 Androgen receptor Presenilin PF01080.17 CDJ44433.1 - 0.01 14.7 1.8 0.011 14.6 1.8 1.1 1 0 0 1 1 1 1 Presenilin SpoIIP PF07454.11 CDJ44433.1 - 0.01 15.3 0.8 0.011 15.2 0.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ44433.1 - 0.016 14.2 2.4 0.017 14.1 2.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FHIPEP PF00771.20 CDJ44433.1 - 0.025 13.1 1.6 0.031 12.8 1.6 1.0 1 0 0 1 1 1 0 FHIPEP family Suf PF05843.14 CDJ44433.1 - 0.026 14.5 5.2 0.029 14.3 5.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ44433.1 - 0.04 13.9 15.0 0.049 13.6 15.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PepSY_TM PF03929.16 CDJ44433.1 - 0.045 13.4 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region ABC2_membrane_2 PF12679.7 CDJ44433.1 - 0.054 12.8 0.2 0.093 12.0 0.3 1.2 1 1 0 1 1 1 0 ABC-2 family transporter protein Rxt3 PF08642.10 CDJ44433.1 - 0.062 14.1 1.6 0.091 13.5 1.6 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Connexin PF00029.19 CDJ44433.1 - 0.072 12.8 0.4 0.089 12.5 0.4 1.1 1 0 0 1 1 1 0 Connexin DUF2828 PF11443.8 CDJ44433.1 - 0.073 11.2 1.6 0.088 10.9 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Ctr PF04145.15 CDJ44433.1 - 0.086 13.5 0.2 0.093 13.3 0.2 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DivIC PF04977.15 CDJ44433.1 - 0.091 12.5 5.9 0.16 11.8 5.9 1.3 1 0 0 1 1 1 0 Septum formation initiator UPF0560 PF10577.9 CDJ44433.1 - 0.1 11.1 10.0 0.13 10.7 10.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TERB2 PF15101.6 CDJ44433.1 - 0.11 12.6 7.8 0.14 12.2 7.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Tim54 PF11711.8 CDJ44433.1 - 0.11 11.3 3.4 0.14 11.0 3.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 V_ATPase_I PF01496.19 CDJ44433.1 - 0.11 10.4 2.1 0.13 10.1 2.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pex26 PF07163.12 CDJ44433.1 - 0.15 11.4 4.2 0.18 11.1 4.2 1.2 1 0 0 1 1 1 0 Pex26 protein OATP PF03137.20 CDJ44433.1 - 0.21 9.9 0.2 0.23 9.7 0.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Asparaginase_2 PF01112.18 CDJ44433.1 - 0.21 10.6 1.3 0.26 10.3 1.3 1.1 1 0 0 1 1 1 0 Asparaginase CLN3 PF02487.17 CDJ44433.1 - 0.23 10.5 0.9 0.29 10.1 0.9 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4407 PF14362.6 CDJ44433.1 - 0.46 9.8 6.4 0.64 9.3 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1180 PF06679.12 CDJ44433.1 - 0.71 10.3 9.6 0.26 11.7 6.8 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1180) RHD3 PF05879.12 CDJ44433.1 - 0.92 7.6 7.5 2.1 6.4 0.2 2.0 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) Conotoxin PF02950.17 CDJ44433.1 - 1.3 10.1 7.8 4.6 8.3 7.8 1.8 1 1 0 1 1 1 0 Conotoxin EIIBC-GUT_N PF03612.14 CDJ44433.1 - 1.3 8.7 4.0 1.8 8.3 4.0 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CNDH2_M PF16869.5 CDJ44433.1 - 2.4 8.9 9.0 0.66 10.7 6.1 1.5 2 0 0 2 2 1 0 PF16858 SprA-related PF12118.8 CDJ44433.1 - 3 6.9 16.9 5.1 6.1 16.9 1.3 1 0 0 1 1 1 0 SprA-related family Spt20 PF12090.8 CDJ44433.1 - 4.3 6.9 25.4 5.6 6.5 25.4 1.1 1 0 0 1 1 1 0 Spt20 family DUF2367 PF10164.9 CDJ44433.1 - 4.3 7.9 4.7 7.3 7.2 4.7 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Presenilin PF01080.17 CDJ44434.1 - 0.00065 18.6 4.5 0.00065 18.6 4.5 2.1 2 0 0 2 2 2 1 Presenilin DUF3807 PF12720.7 CDJ44434.1 - 0.0063 16.8 30.6 0.18 12.0 12.9 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3807) RNA_pol_Rpc4 PF05132.14 CDJ44434.1 - 0.007 16.8 2.5 0.007 16.8 2.5 3.0 3 0 0 3 3 3 1 RNA polymerase III RPC4 MPM1 PF17234.2 CDJ44434.1 - 0.011 16.0 3.2 0.011 16.0 3.2 3.4 3 1 0 3 3 2 0 Mitochondrial peculiar membrane protein 1 DUF2052 PF09747.9 CDJ44434.1 - 0.011 15.8 21.7 0.17 12.0 4.7 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Senescence_reg PF04520.13 CDJ44434.1 - 0.066 14.1 15.7 0.53 11.1 0.8 2.5 2 0 0 2 2 2 0 Senescence regulator Endostatin PF06482.11 CDJ44434.1 - 0.085 12.3 20.5 0.076 12.5 6.3 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin DUF913 PF06025.12 CDJ44434.1 - 0.087 11.8 11.2 0.34 9.8 2.9 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF2126 PF09899.9 CDJ44434.1 - 0.091 10.8 19.7 0.18 9.8 6.9 2.0 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) ATP11 PF06644.11 CDJ44434.1 - 0.24 11.1 25.2 0.18 11.6 9.6 2.4 2 0 0 2 2 2 0 ATP11 protein FAM176 PF14851.6 CDJ44434.1 - 0.39 10.4 14.7 0.25 11.0 3.0 2.7 3 0 0 3 3 3 0 FAM176 family CCSAP PF15748.5 CDJ44434.1 - 0.57 10.3 27.0 1.2 9.2 11.3 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated PIP5K PF01504.18 CDJ44434.1 - 0.81 8.9 21.0 1.2 8.3 2.4 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Pkinase_fungal PF17667.1 CDJ44434.1 - 0.83 8.4 11.8 0.2 10.4 3.2 2.1 2 0 0 2 2 2 0 Fungal protein kinase SspB PF04386.13 CDJ44434.1 - 0.83 9.5 18.9 1.1 9.2 7.5 2.4 2 0 0 2 2 2 0 Stringent starvation protein B Afi1 PF07792.12 CDJ44434.1 - 0.87 10.1 23.9 1.2 9.6 8.3 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking MMR1 PF08505.10 CDJ44434.1 - 1.2 9.4 34.5 0.67 10.2 12.1 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Ferlin_C PF16165.5 CDJ44434.1 - 1.2 9.0 4.9 13 5.8 0.3 2.5 2 0 0 2 2 2 0 Ferlin C-terminus DUF4050 PF13259.6 CDJ44434.1 - 1.3 9.3 20.9 2.9 8.2 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) SLC12 PF03522.15 CDJ44434.1 - 1.3 7.9 24.7 1.5 7.7 10.2 2.1 2 0 0 2 2 2 0 Solute carrier family 12 RuvC_III PF18541.1 CDJ44434.1 - 1.4 8.9 16.8 0.6 10.0 1.7 2.6 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 NARP1 PF12569.8 CDJ44434.1 - 1.4 7.8 28.7 0.065 12.1 11.6 2.7 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 CDJ44434.1 - 1.7 8.4 26.6 0.46 10.3 10.0 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2464 PF10240.9 CDJ44434.1 - 1.7 8.1 12.0 0.11 12.0 1.4 2.2 2 0 0 2 2 2 0 Multivesicular body subunit 12 AAA_11 PF13086.6 CDJ44434.1 - 1.8 8.3 25.0 1.7 8.4 9.0 2.2 2 0 0 2 2 2 0 AAA domain Zip PF02535.22 CDJ44434.1 - 2.7 7.1 11.0 7.3 5.7 0.3 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter FAM60A PF15396.6 CDJ44434.1 - 4.7 7.2 20.6 6 6.8 8.8 2.3 2 0 0 2 2 2 0 Protein Family FAM60A PA26 PF04636.13 CDJ44434.1 - 5.1 5.9 20.0 1.8 7.4 6.5 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) EOS1 PF12326.8 CDJ44434.1 - 5.2 7.0 14.5 1.3 8.9 4.0 2.3 2 0 0 2 2 2 0 N-glycosylation protein FHIPEP PF00771.20 CDJ44434.1 - 5.2 5.4 21.4 2 6.8 5.6 2.5 2 1 0 2 2 2 0 FHIPEP family PGA_cap PF09587.10 CDJ44434.1 - 5.5 6.3 11.1 3 7.2 1.3 2.3 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap CLN3 PF02487.17 CDJ44434.1 - 6.4 5.7 19.9 3.3 6.6 8.6 2.2 2 0 0 2 2 2 0 CLN3 protein Folate_carrier PF01770.18 CDJ44434.1 - 9.7 4.8 13.2 8.4 5.0 5.6 2.4 2 0 0 2 2 2 0 Reduced folate carrier Glyco_hydro_9 PF00759.19 CDJ44435.1 - 0.54 9.6 2.7 0.66 9.3 2.7 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Ank_4 PF13637.6 CDJ44436.1 - 5.8e-05 23.6 0.0 6.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ44436.1 - 0.00031 21.3 0.0 0.00034 21.2 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ44436.1 - 0.00094 19.5 0.1 0.002 18.5 0.0 1.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CDJ44436.1 - 0.015 15.8 0.0 0.062 13.9 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 CDJ44436.1 - 0.018 15.4 0.0 0.022 15.1 0.0 1.3 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Med6 PF04934.14 CDJ44437.1 - 0.00038 20.3 0.2 0.0014 18.4 0.0 1.9 2 0 0 2 2 2 1 MED6 mediator sub complex component FAM76 PF16046.5 CDJ44437.1 - 0.017 14.5 8.2 0.028 13.8 8.2 1.2 1 0 0 1 1 1 0 FAM76 protein SR-25 PF10500.9 CDJ44437.1 - 0.12 12.0 29.4 0.23 11.0 29.4 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase_fungal PF17667.1 CDJ44437.1 - 0.3 9.8 7.3 0.39 9.4 7.3 1.1 1 0 0 1 1 1 0 Fungal protein kinase LAP1C PF05609.12 CDJ44437.1 - 0.3 10.1 16.3 0.37 9.8 16.3 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_S64 PF08192.11 CDJ44437.1 - 0.31 9.5 16.4 0.4 9.1 16.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4615 PF15393.6 CDJ44437.1 - 0.54 10.8 15.2 7.6 7.1 15.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) DUF5471 PF17565.2 CDJ44437.1 - 0.94 9.8 6.7 3.4 8.0 6.7 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5471) NAM-associated PF14303.6 CDJ44437.1 - 1.2 9.8 15.5 1.9 9.2 15.5 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain BAF1_ABF1 PF04684.13 CDJ44437.1 - 1.3 8.0 13.4 1.5 7.8 13.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RAP1 PF07218.11 CDJ44437.1 - 1.3 7.2 14.0 1.6 6.9 14.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF966 PF06136.13 CDJ44437.1 - 1.9 8.1 18.7 2.4 7.8 18.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FAM199X PF15814.5 CDJ44437.1 - 2.8 6.9 21.8 3.8 6.5 21.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X Ndc1_Nup PF09531.10 CDJ44437.1 - 3 6.4 19.4 4 6.0 19.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IQCJ-SCHIP1 PF15157.6 CDJ44437.1 - 3.1 7.6 13.4 6.2 6.7 13.3 1.5 1 1 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DUF515 PF04415.12 CDJ44437.1 - 3.3 6.0 16.6 4.4 5.6 16.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Herpes_pp85 PF04637.12 CDJ44437.1 - 4.9 5.4 11.5 6.5 5.0 11.5 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SRP-alpha_N PF04086.13 CDJ44437.1 - 8.7 6.2 15.6 12 5.8 15.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Peptidase_M24 PF00557.24 CDJ44439.1 - 6.1e-15 55.5 0.0 6.8e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24 PF00557.24 CDJ44440.1 - 2.7e-20 72.9 0.0 2.7e-20 72.9 0.0 1.4 2 0 0 2 2 2 1 Metallopeptidase family M24 Selenoprotein_S PF06936.11 CDJ44440.1 - 0.1 12.4 2.0 0.16 11.8 2.0 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF2190 PF09956.9 CDJ44440.1 - 0.35 11.4 7.2 0.14 12.6 4.3 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) DUF2529 PF10740.9 CDJ44441.1 - 0.0054 16.4 4.0 0.049 13.3 0.2 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF2529) SUIM_assoc PF16619.5 CDJ44441.1 - 0.025 14.7 3.5 0.025 14.7 3.5 4.4 6 0 0 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 Peptidase_S46 PF10459.9 CDJ44441.1 - 9.1 4.8 14.7 2.7 6.6 6.8 2.1 2 0 0 2 2 2 0 Peptidase S46 DUF4661 PF15576.6 CDJ44444.1 - 0.073 13.0 4.4 0.081 12.8 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) ANAPC4_WD40 PF12894.7 CDJ44447.1 - 4.4e-11 42.9 0.0 4.9e-07 29.9 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ44447.1 - 0.0001 23.0 0.3 0.081 13.8 0.0 3.3 4 0 0 4 4 4 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 CDJ44447.1 - 0.018 15.1 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region RAB3GAP2_N PF14655.6 CDJ44447.1 - 0.031 13.6 1.4 11 5.1 0.0 3.0 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus eIF2A PF08662.11 CDJ44447.1 - 0.062 13.2 0.0 0.15 11.9 0.0 1.6 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Asparaginase PF00710.20 CDJ44448.1 - 2.5e-44 151.1 0.0 8.3e-44 149.4 0.0 1.8 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CDJ44448.1 - 1.6e-23 83.1 0.6 9.6e-23 80.6 0.1 2.3 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Hydantoinase_A PF01968.18 CDJ44448.1 - 0.062 12.5 0.4 0.36 10.1 0.0 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase SR-25 PF10500.9 CDJ44448.1 - 2.8 7.5 15.7 5.6 6.5 15.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATP-synt_E PF05680.12 CDJ44449.1 - 0.045 14.1 5.1 0.051 13.9 5.1 1.3 1 0 0 1 1 1 0 ATP synthase E chain Pex14_N PF04695.13 CDJ44449.1 - 0.11 13.2 13.8 0.12 13.0 13.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1180 PF06679.12 CDJ44449.1 - 0.13 12.6 1.7 0.14 12.5 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PPL5 PF18168.1 CDJ44449.1 - 0.14 11.4 2.4 0.13 11.5 2.4 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 CDJ44449.1 - 0.29 9.8 8.9 0.29 9.8 8.9 1.0 1 0 0 1 1 1 0 Presenilin PRC2_HTH_1 PF18118.1 CDJ44449.1 - 0.31 11.9 5.5 0.38 11.6 5.5 1.1 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Sec62 PF03839.16 CDJ44449.1 - 0.42 10.1 3.9 0.39 10.2 3.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Stig1 PF04885.13 CDJ44449.1 - 0.42 11.1 3.6 0.49 10.9 3.6 1.1 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 CLN3 PF02487.17 CDJ44449.1 - 0.45 9.5 4.0 0.41 9.6 4.0 1.0 1 0 0 1 1 1 0 CLN3 protein SpoIIP PF07454.11 CDJ44449.1 - 0.48 9.8 6.2 0.46 9.9 6.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PIP5K PF01504.18 CDJ44449.1 - 0.52 9.5 5.3 0.52 9.5 5.3 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Glycophorin_A PF01102.18 CDJ44449.1 - 0.53 10.5 2.0 0.88 9.8 2.0 1.4 1 1 0 1 1 1 0 Glycophorin A Rrn6 PF10214.9 CDJ44449.1 - 0.91 7.9 15.0 0.97 7.8 15.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TFIIA PF03153.13 CDJ44449.1 - 0.96 9.4 25.3 1 9.3 25.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 CDJ44449.1 - 1.7 8.4 5.3 1.7 8.3 5.3 1.1 1 0 0 1 1 1 0 Connexin MDM10 PF12519.8 CDJ44449.1 - 1.8 7.3 5.6 1.9 7.2 5.6 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Ndc1_Nup PF09531.10 CDJ44449.1 - 2.6 6.6 6.9 2.8 6.5 6.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3488 PF11992.8 CDJ44449.1 - 3 6.7 5.5 3.4 6.5 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Neur_chan_memb PF02932.16 CDJ44449.1 - 3.5 7.6 5.8 3.5 7.6 5.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OATP PF03137.20 CDJ44449.1 - 3.8 5.7 4.5 4.1 5.6 4.5 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Kei1 PF08552.11 CDJ44449.1 - 6.9 6.5 6.2 7.9 6.3 6.2 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Folliculin PF11704.8 CDJ44449.1 - 9.9 6.0 9.4 11 5.9 9.4 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Pkinase PF00069.25 CDJ44450.1 - 2.8e-21 76.1 0.0 4.9e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain EF-hand_7 PF13499.6 CDJ44450.1 - 7.6e-18 64.7 0.9 4.2e-08 33.5 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ44450.1 - 3.3e-17 60.7 1.1 0.0011 18.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDJ44450.1 - 8.1e-14 50.3 0.7 0.00079 19.2 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CDJ44450.1 - 1.4e-11 44.0 0.8 0.00031 20.5 0.0 4.0 1 1 3 4 4 4 4 EF-hand domain pair Pkinase_Tyr PF07714.17 CDJ44450.1 - 0.00011 21.6 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SPARC_Ca_bdg PF10591.9 CDJ44450.1 - 0.0024 18.2 0.0 0.14 12.5 0.0 2.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDJ44450.1 - 0.0028 17.9 0.0 1.8 9.0 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 CDJ44450.1 - 0.0035 16.8 3.1 2.1 8.0 0.0 3.6 4 0 0 4 4 4 2 EF hand Kinase-like PF14531.6 CDJ44450.1 - 0.034 13.5 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like EF-hand_4 PF12763.7 CDJ44450.1 - 0.1 12.6 0.3 6.8 6.7 0.1 2.6 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Roughex PF06020.11 CDJ44451.1 - 0.32 10.0 4.1 0.32 10.0 4.1 1.0 1 0 0 1 1 1 0 Drosophila roughex protein TMEM208_SND2 PF05620.11 CDJ44451.1 - 1.3 8.8 2.8 1.6 8.5 2.8 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 HD_assoc PF13286.6 CDJ44452.1 - 0.6 10.7 5.5 1.1 9.9 1.5 2.3 1 1 1 2 2 2 0 Phosphohydrolase-associated domain Fis1_TPR_C PF14853.6 CDJ44454.1 - 1.2e-16 60.5 0.1 1.3e-16 60.3 0.1 1.0 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 CDJ44454.1 - 0.00025 20.9 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ44454.1 - 0.0049 17.5 0.2 0.0075 16.9 0.1 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ44454.1 - 0.015 15.5 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ44454.1 - 0.022 15.2 0.0 0.028 14.9 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ44454.1 - 0.023 14.8 0.1 0.03 14.4 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ44454.1 - 0.033 14.8 0.0 0.054 14.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ44454.1 - 0.048 13.5 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ44454.1 - 0.081 13.0 0.2 0.11 12.6 0.2 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat Neuropep_like PF15161.6 CDJ44454.1 - 0.2 11.4 0.1 0.28 10.9 0.1 1.2 1 0 0 1 1 1 0 Neuropeptide-like ARS2 PF04959.13 CDJ44455.1 - 9.1e-07 29.4 0.4 9.1e-07 29.4 0.4 2.3 1 1 1 2 2 1 1 Arsenite-resistance protein 2 FAM176 PF14851.6 CDJ44455.1 - 0.00021 21.0 1.4 0.00046 19.9 1.4 1.6 1 0 0 1 1 1 1 FAM176 family DUF4187 PF13821.6 CDJ44455.1 - 0.00026 20.7 0.1 0.0013 18.4 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RRN3 PF05327.11 CDJ44455.1 - 0.005 15.5 0.2 0.0055 15.3 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 SR-25 PF10500.9 CDJ44455.1 - 0.0061 16.2 6.4 0.0061 16.2 6.4 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Peptidase_S64 PF08192.11 CDJ44455.1 - 0.015 13.8 4.5 0.032 12.8 4.5 1.5 1 0 0 1 1 1 0 Peptidase family S64 DDHD PF02862.17 CDJ44455.1 - 0.023 14.9 0.9 0.04 14.1 0.9 1.5 1 0 0 1 1 1 0 DDHD domain Spt20 PF12090.8 CDJ44455.1 - 0.055 13.1 23.1 0.065 12.8 16.5 2.4 2 0 0 2 2 2 0 Spt20 family Rtf2 PF04641.12 CDJ44455.1 - 0.073 12.4 6.5 1.1 8.6 2.6 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger CPSF100_C PF13299.6 CDJ44455.1 - 0.085 13.0 2.3 0.15 12.2 2.3 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Bul1_C PF04426.12 CDJ44455.1 - 0.089 12.2 5.2 0.14 11.6 5.2 1.2 1 0 0 1 1 1 0 Bul1 C terminus GREB1 PF15782.5 CDJ44455.1 - 0.16 9.1 9.5 0.21 8.7 9.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2052 PF09747.9 CDJ44455.1 - 0.17 12.0 8.1 0.34 11.0 8.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TFIIA PF03153.13 CDJ44455.1 - 0.2 11.6 20.9 0.15 12.0 16.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ABC2_membrane_3 PF12698.7 CDJ44455.1 - 0.29 10.2 0.0 0.38 9.8 0.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4674 PF15719.5 CDJ44455.1 - 0.48 10.4 11.1 5.6 6.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) Presenilin PF01080.17 CDJ44455.1 - 0.7 8.6 7.1 1 8.1 7.1 1.2 1 0 0 1 1 1 0 Presenilin DUF908 PF06012.12 CDJ44455.1 - 0.89 8.9 9.3 1.4 8.3 9.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4407 PF14362.6 CDJ44455.1 - 0.91 8.8 3.8 1.6 8.0 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC106 PF15794.5 CDJ44455.1 - 0.93 9.2 9.3 1.8 8.2 9.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Ndc1_Nup PF09531.10 CDJ44455.1 - 1 8.0 6.2 1.3 7.6 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup baeRF_family12 PF18856.1 CDJ44455.1 - 1.4 9.5 6.5 3.9 8.1 6.5 1.8 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 Hid1 PF12722.7 CDJ44455.1 - 4.7 5.2 8.1 6.1 4.8 8.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAP1 PF08601.10 CDJ44457.1 - 0.064 13.0 6.7 0.062 13.0 6.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 IMUP PF15761.5 CDJ44457.1 - 2.2 9.0 25.2 2.9 8.6 0.6 2.5 1 1 2 3 3 3 0 Immortalisation up-regulated protein LPMO_10 PF03067.15 CDJ44458.1 - 0.23 12.1 5.9 0.28 11.8 5.9 1.2 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF1387 PF07139.11 CDJ44458.1 - 0.81 9.4 9.5 0.93 9.2 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Raftlin PF15250.6 CDJ44458.1 - 1.1 7.9 12.0 1.3 7.7 12.0 1.0 1 0 0 1 1 1 0 Raftlin MMR1 PF08505.10 CDJ44458.1 - 2.7 8.2 10.9 3.1 8.0 10.9 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PTPS PF01242.19 CDJ44460.1 - 2.4e-06 27.5 0.0 2.4e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase MAP7 PF05672.11 CDJ44461.1 - 0.0053 16.5 18.2 0.0075 16.0 18.2 1.2 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family TFIIA PF03153.13 CDJ44461.1 - 0.0068 16.5 24.2 0.0086 16.1 24.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 CDJ44461.1 - 3.8 6.8 10.2 5.7 6.2 10.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) E1-E2_ATPase PF00122.20 CDJ44462.1 - 2.1e-15 56.7 0.0 3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase DUF2722 PF10846.8 CDJ44463.1 - 0.0004 19.5 5.2 0.0004 19.5 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ44463.1 - 0.011 15.8 10.0 0.011 15.8 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM222A PF15258.6 CDJ44463.1 - 0.2 10.7 8.9 0.17 11.0 8.9 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Suf PF05843.14 CDJ44463.1 - 0.6 10.0 4.7 0.69 9.8 4.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ44463.1 - 1.4 7.6 3.4 1.8 7.3 3.4 1.1 1 0 0 1 1 1 0 Presenilin ketoacyl-synt PF00109.26 CDJ44465.1 - 3.2e-71 239.9 0.4 4.5e-71 239.4 0.4 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CDJ44465.1 - 3.3e-38 130.3 0.2 8e-38 129.1 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 CDJ44465.1 - 1.3e-12 47.9 0.5 2.3e-12 47.1 0.5 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 CDJ44465.1 - 0.0002 21.8 0.1 0.00043 20.7 0.1 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 CDJ44465.1 - 0.0031 17.3 1.2 0.012 15.5 1.2 2.0 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 CDJ44465.1 - 0.015 14.7 0.3 0.039 13.3 0.3 1.7 1 1 0 1 1 1 0 Thiolase, N-terminal domain UDPGT PF00201.18 CDJ44466.1 - 0.0011 17.9 9.8 0.0011 17.9 9.8 1.3 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DUF3450 PF11932.8 CDJ44466.1 - 0.0018 17.6 20.9 0.0018 17.6 20.9 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) HIP1_clath_bdg PF16515.5 CDJ44466.1 - 0.0062 17.1 15.9 0.0062 17.1 15.9 3.1 1 1 2 3 3 3 2 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 CDJ44466.1 - 0.037 14.6 52.7 0.1 13.1 18.5 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region LMBR1 PF04791.16 CDJ44466.1 - 0.04 12.8 16.8 0.069 12.0 16.8 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein AAA_13 PF13166.6 CDJ44466.1 - 0.065 11.9 30.9 0.076 11.6 30.9 1.0 1 0 0 1 1 1 0 AAA domain DUF2207 PF09972.9 CDJ44466.1 - 0.1 11.4 0.4 0.15 10.8 0.2 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) CENP-F_leu_zip PF10473.9 CDJ44466.1 - 0.12 12.4 40.1 0.13 12.3 13.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 CDJ44466.1 - 0.12 13.0 26.7 0.14 12.8 6.9 2.2 2 0 0 2 2 2 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 CDJ44466.1 - 0.21 11.1 49.7 0.75 9.3 28.5 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 GREB1 PF15782.5 CDJ44466.1 - 0.41 7.7 20.5 0.49 7.5 20.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-C4H2 PF10146.9 CDJ44466.1 - 1.2 9.4 20.3 1.4 9.2 20.3 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF3584 PF12128.8 CDJ44466.1 - 1.4 6.4 51.1 1.8 6.0 51.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 CDJ44466.1 - 1.9 8.9 40.1 82 3.6 40.1 2.0 1 1 0 1 1 1 0 Fez1 FUSC PF04632.12 CDJ44466.1 - 2.1 6.8 31.2 4 5.8 31.2 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 CDJ44466.1 - 2.1 8.4 27.6 1.3 9.0 13.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CDJ44466.1 - 2.5 8.2 20.5 0.53 10.3 6.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BRE1 PF08647.11 CDJ44466.1 - 2.8 8.1 45.8 0.84 9.7 17.0 2.7 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase EIF4E-T PF10477.9 CDJ44466.1 - 2.9 6.6 30.7 3.2 6.4 30.7 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E FapA PF03961.13 CDJ44466.1 - 4 5.9 31.8 1.5 7.3 17.9 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Syntaxin-6_N PF09177.11 CDJ44466.1 - 5.1 7.7 25.0 5.3 7.7 10.4 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 CDJ44466.1 - 6.7 5.5 44.7 33 3.2 44.1 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein MAP65_ASE1 PF03999.12 CDJ44466.1 - 6.7 5.3 28.0 7.9 5.0 28.0 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF3806 PF12713.7 CDJ44468.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) Urb2 PF10441.9 CDJ44469.1 - 0.19 11.6 2.4 0.37 10.7 2.4 1.4 1 0 0 1 1 1 0 Urb2/Npa2 family Miga PF10265.9 CDJ44470.1 - 0.0036 16.4 12.7 0.0046 16.0 12.7 1.1 1 0 0 1 1 1 1 Mitoguardin PEHE PF15275.6 CDJ44470.1 - 0.013 16.1 8.4 0.022 15.4 8.4 1.4 1 0 0 1 1 1 0 PEHE domain DUF1645 PF07816.11 CDJ44470.1 - 0.036 14.6 9.2 0.06 13.9 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Tam41_Mmp37 PF09139.11 CDJ44470.1 - 0.039 13.4 6.8 0.053 13.0 6.8 1.2 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial PepSY_TM PF03929.16 CDJ44470.1 - 0.16 11.6 0.5 0.2 11.3 0.5 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Peptidase_S64 PF08192.11 CDJ44470.1 - 0.19 10.2 11.9 0.21 10.0 11.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 CDJ44470.1 - 0.21 10.3 7.3 0.22 10.3 7.3 1.2 1 0 0 1 1 1 0 Presenilin FHIPEP PF00771.20 CDJ44470.1 - 1.8 6.9 8.8 2.4 6.5 8.8 1.1 1 0 0 1 1 1 0 FHIPEP family DUF2813 PF11398.8 CDJ44470.1 - 1.8 7.7 16.3 2.7 7.2 16.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) DUF3492 PF11997.8 CDJ44470.1 - 1.9 8.1 5.6 2.7 7.7 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) FliP PF00813.20 CDJ44470.1 - 2 8.3 6.4 3.5 7.5 6.4 1.3 1 0 0 1 1 1 0 FliP family DUF4449 PF14613.6 CDJ44470.1 - 2 8.5 12.4 5.1 7.2 10.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) GvpL_GvpF PF06386.11 CDJ44470.1 - 2.1 8.2 12.4 3.7 7.4 12.4 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Endonuc_Holl PF10107.9 CDJ44470.1 - 2.5 8.0 11.5 4.1 7.2 11.5 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase HI0933_like PF03486.14 CDJ44470.1 - 3.5 6.2 11.4 5.2 5.7 11.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Sec62 PF03839.16 CDJ44470.1 - 3.5 7.1 7.4 5.1 6.5 7.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 CLN3 PF02487.17 CDJ44470.1 - 4.4 6.3 7.7 6.2 5.8 7.7 1.2 1 0 0 1 1 1 0 CLN3 protein Virul_fac_BrkB PF03631.15 CDJ44470.1 - 5.5 6.5 5.5 8.9 5.8 5.5 1.4 1 0 0 1 1 1 0 Virulence factor BrkB PepSY_TM_like_2 PF16357.5 CDJ44470.1 - 7.2 6.5 9.7 11 5.9 9.7 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like Spore_III_AF PF09581.10 CDJ44470.1 - 7.9 6.5 13.4 13 5.7 13.4 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) TALPID3 PF15324.6 CDJ44470.1 - 8.3 3.9 23.5 8.2 4.0 23.5 1.1 1 0 0 1 1 1 0 Hedgehog signalling target DUF1635 PF07795.11 CDJ44470.1 - 8.6 6.1 30.1 0.035 14.0 19.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Med3 PF11593.8 CDJ44471.1 - 0.36 10.0 9.5 0.024 13.8 5.0 1.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal LEA_3 PF03242.13 CDJ44471.1 - 1.7 9.4 6.4 13 6.5 0.4 2.3 2 0 0 2 2 2 0 Late embryogenesis abundant protein Spt20 PF12090.8 CDJ44471.1 - 2.6 7.6 10.8 4.3 6.9 10.8 1.3 1 0 0 1 1 1 0 Spt20 family DUF3043 PF11241.8 CDJ44471.1 - 7.3 6.6 7.6 13 5.7 6.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Coatomer_WDAD PF04053.14 CDJ44472.1 - 1.6e-53 182.4 0.0 2.1e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CDJ44472.1 - 3.7e-13 49.7 1.1 0.00087 20.1 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ44472.1 - 0.0042 17.4 0.0 3.4 8.0 0.0 4.0 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain LUC7 PF03194.15 CDJ44474.1 - 5e-05 23.1 1.3 5e-05 23.1 1.3 2.1 2 1 0 2 2 2 1 LUC7 N_terminus APG6_N PF17675.1 CDJ44474.1 - 4.6 7.8 7.9 0.48 11.0 1.8 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Memo PF01875.17 CDJ44475.1 - 4e-18 65.5 0.0 4.4e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein TLD PF07534.16 CDJ44478.1 - 5.8e-13 49.3 0.1 6.6e-13 49.1 0.1 1.0 1 0 0 1 1 1 1 TLD RskA PF10099.9 CDJ44480.1 - 0.017 15.4 8.4 0.027 14.8 8.4 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ44480.1 - 0.37 10.9 7.4 0.73 9.9 7.4 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Virul_Fac PF10139.9 CDJ44480.1 - 0.48 8.6 3.1 0.54 8.4 3.1 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor ATP_synt_H PF05493.13 CDJ44481.1 - 2.2e-18 66.4 6.4 2.7e-18 66.2 6.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.6 CDJ44481.1 - 1.4 8.5 4.7 1.6 8.4 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF384 PF04064.13 CDJ44483.1 - 3.8e-09 36.3 0.1 3.8e-09 36.3 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF2828 PF11443.8 CDJ44483.1 - 0.002 16.3 12.9 0.009 14.2 3.7 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF2828) CFIA_Pcf11 PF11526.8 CDJ44483.1 - 0.035 14.6 0.4 0.035 14.6 0.4 4.4 5 0 0 5 5 5 0 Subunit of cleavage factor IA Pcf11 DUF4834 PF16118.5 CDJ44483.1 - 0.053 14.5 2.3 0.053 14.5 2.3 4.5 4 1 0 4 4 4 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CDJ44483.1 - 0.064 11.2 15.4 0.14 10.0 5.5 2.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Pex24p PF06398.11 CDJ44483.1 - 0.28 10.1 5.4 0.056 12.4 0.4 2.1 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Serinc PF03348.15 CDJ44483.1 - 1.5 7.6 7.7 1.9 7.3 1.6 2.4 2 0 0 2 2 2 0 Serine incorporator (Serinc) Presenilin PF01080.17 CDJ44483.1 - 1.7 7.3 32.1 0.69 8.6 4.5 3.1 3 0 0 3 3 3 0 Presenilin AUX_IAA PF02309.16 CDJ44483.1 - 7.5 6.3 12.0 4.7 7.0 0.7 2.7 3 0 0 3 3 3 0 AUX/IAA family Peptidase_C14 PF00656.22 CDJ44484.1 - 0.0002 21.4 0.0 0.0002 21.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain DEAD PF00270.29 CDJ44485.1 - 4.2e-10 39.7 0.1 6.9e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ44485.1 - 0.056 13.4 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SR-25 PF10500.9 CDJ44485.1 - 2.2 7.8 7.1 3.9 7.0 7.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ44485.1 - 4.8 7.1 18.5 6.2 6.7 18.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAN_1 PF00024.26 CDJ44487.1 - 0.016 15.2 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 PAN domain DUF4148 PF13663.6 CDJ44487.1 - 2.1 8.6 8.5 22 5.3 1.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) SRP-alpha_N PF04086.13 CDJ44488.1 - 0.13 12.2 1.7 0.16 11.9 1.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MDM10 PF12519.8 CDJ44489.1 - 0.018 14.0 6.6 0.058 12.3 6.6 1.9 1 1 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Acetyltransf_1 PF00583.25 CDJ44491.1 - 1.7e-07 31.5 0.1 0.014 15.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ44491.1 - 0.01 16.2 0.0 0.21 12.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SUIM_assoc PF16619.5 CDJ44491.1 - 0.053 13.6 1.7 0.099 12.7 1.7 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ44491.1 - 2.6 8.0 14.2 3.5 7.5 14.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.6 CDJ44494.1 - 0.41 11.2 38.4 0.64 10.6 38.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 CDJ44494.1 - 5.3 5.6 37.7 5.6 5.5 37.7 1.1 1 0 0 1 1 1 0 Hamartin protein DEAD PF00270.29 CDJ44495.1 - 8.4e-06 25.7 0.0 3e-05 23.9 0.0 1.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase Ribosomal_60s PF00428.19 CDJ44495.1 - 1.3 9.7 6.4 2.4 8.8 6.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein TAF4 PF05236.14 CDJ44496.1 - 0.16 11.7 19.0 0.2 11.4 19.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF4757 PF15949.5 CDJ44496.1 - 0.81 10.1 11.9 0.91 10.0 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) CRISPR_Cse2 PF09485.10 CDJ44496.1 - 1.5 9.3 13.0 2.6 8.5 12.8 1.4 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) BAF1_ABF1 PF04684.13 CDJ44496.1 - 6.1 5.8 17.5 6.2 5.8 17.5 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Dsh_C PF12316.8 CDJ44496.1 - 6.9 7.0 22.6 7.4 6.9 22.6 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Dicty_REP PF05086.12 CDJ44496.1 - 7.7 4.4 7.2 8.1 4.3 7.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_M16_C PF05193.21 CDJ44497.1 - 3e-06 27.4 0.0 2e-05 24.7 0.0 2.4 1 1 0 1 1 1 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 CDJ44497.1 - 0.0037 16.4 2.2 0.0056 15.9 2.2 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16 PF00675.20 CDJ44497.1 - 0.023 14.7 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) SR-25 PF10500.9 CDJ44497.1 - 1.8 8.1 15.3 3.9 7.0 1.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ44498.1 - 0.43 9.3 10.5 0.38 9.5 3.9 2.4 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 CDJ44498.1 - 0.5 10.4 6.9 4.4 7.3 1.8 2.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ44498.1 - 0.53 9.3 4.1 1.6 7.7 0.5 2.3 2 0 0 2 2 2 0 CLN3 protein DUF4834 PF16118.5 CDJ44498.1 - 1.2 10.2 15.6 4.7 8.3 4.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) eIF-3_zeta PF05091.12 CDJ44498.1 - 4.4 6.2 15.3 0.017 14.1 2.1 2.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF719 PF05334.13 CDJ44498.1 - 6.9 6.8 11.3 15 5.7 2.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF719) Adenylsucc_synt PF00709.21 CDJ44499.1 - 1.6e-86 290.9 0.0 1.8e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase CCSAP PF15748.5 CDJ44502.1 - 0.0079 16.4 38.2 0.0079 16.4 38.2 4.9 5 0 0 5 5 5 3 Centriole, cilia and spindle-associated RskA PF10099.9 CDJ44503.1 - 1.1e-06 29.1 0.9 1.1e-06 29.1 0.9 3.4 1 1 2 3 3 3 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ44503.1 - 0.45 10.1 23.1 0.27 10.8 13.4 2.1 2 0 0 2 2 2 0 Spt20 family FSA_C PF10479.9 CDJ44503.1 - 0.9 7.6 5.6 1.2 7.2 5.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RNA_pol_Rpc4 PF05132.14 CDJ44503.1 - 2.3 8.6 13.7 2.1 8.8 4.8 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF755 PF05501.11 CDJ44504.1 - 0.018 15.3 4.1 0.018 15.3 4.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF755) DUF2722 PF10846.8 CDJ44505.1 - 0.0007 18.7 38.4 0.019 13.9 25.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Eapp_C PF10238.9 CDJ44505.1 - 0.0018 18.4 13.9 0.041 13.9 8.5 2.1 2 0 0 2 2 2 1 E2F-associated phosphoprotein TFB6 PF17110.5 CDJ44505.1 - 0.0022 17.8 10.3 0.0029 17.4 4.6 2.1 2 0 0 2 2 2 1 Subunit 11 of the general transcription factor TFIIH DUF775 PF05603.12 CDJ44505.1 - 0.0025 17.4 16.5 0.0055 16.3 7.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF775) BRF1 PF07741.13 CDJ44505.1 - 0.004 17.5 13.4 0.94 9.9 10.5 2.2 2 0 0 2 2 2 1 Brf1-like TBP-binding domain CSG2 PF16965.5 CDJ44505.1 - 0.0048 15.9 3.5 0.0048 15.9 3.5 1.8 2 0 0 2 2 2 1 Ceramide synthase regulator DUF719 PF05334.13 CDJ44505.1 - 0.0049 17.1 9.3 0.018 15.3 2.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF719) SPG4 PF17325.2 CDJ44505.1 - 0.0052 17.9 11.5 0.0071 17.4 4.6 2.2 2 0 0 2 2 2 1 Stationary phase protein 4 Connexin PF00029.19 CDJ44505.1 - 0.0081 15.9 11.2 0.0084 15.9 5.1 2.1 2 0 0 2 2 2 1 Connexin Pex14_N PF04695.13 CDJ44505.1 - 0.009 16.7 16.2 0.009 16.7 16.2 2.2 1 1 1 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 CDJ44505.1 - 0.0095 16.9 22.3 0.18 12.8 12.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) SpoIIP PF07454.11 CDJ44505.1 - 0.011 15.2 17.0 0.016 14.7 9.2 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) MAM33 PF02330.16 CDJ44505.1 - 0.014 15.4 16.2 0.072 13.0 7.9 2.1 2 0 0 2 2 2 0 Mitochondrial glycoprotein RR_TM4-6 PF06459.12 CDJ44505.1 - 0.019 14.8 14.2 0.023 14.5 6.7 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Rtf2 PF04641.12 CDJ44505.1 - 0.027 13.9 10.1 0.083 12.2 6.4 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger DUF3306 PF11748.8 CDJ44505.1 - 0.027 15.3 13.0 0.35 11.7 6.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF5523 PF17661.1 CDJ44505.1 - 0.034 13.9 17.0 0.052 13.2 8.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) PTPRCAP PF15713.5 CDJ44505.1 - 0.038 14.3 18.3 0.099 12.9 10.0 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated GEN1_C PF18380.1 CDJ44505.1 - 0.045 14.6 6.6 0.18 12.7 2.8 2.2 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Afi1 PF07792.12 CDJ44505.1 - 0.047 14.2 13.3 0.18 12.3 7.2 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4770 PF15994.5 CDJ44505.1 - 0.058 13.6 15.8 0.76 10.0 10.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) V_ATPase_I PF01496.19 CDJ44505.1 - 0.058 11.3 15.5 0.019 13.0 8.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3381 PF11861.8 CDJ44505.1 - 0.065 13.0 21.2 0.61 9.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) ATAD4 PF15321.6 CDJ44505.1 - 0.07 14.5 9.8 0.55 11.6 5.5 2.2 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DUF3402 PF11882.8 CDJ44505.1 - 0.071 12.2 14.5 0.052 12.7 8.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) DUF4484 PF14831.6 CDJ44505.1 - 0.074 13.1 10.5 0.71 9.9 6.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) RLL PF10036.9 CDJ44505.1 - 0.08 12.8 16.1 0.058 13.2 7.0 2.2 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein RXT2_N PF08595.11 CDJ44505.1 - 0.082 12.9 11.9 0.033 14.2 3.6 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Spt20 PF12090.8 CDJ44505.1 - 0.083 12.5 58.3 0.19 11.3 8.4 2.1 2 0 0 2 2 2 0 Spt20 family DUF3408 PF11888.8 CDJ44505.1 - 0.086 13.0 20.8 0.036 14.2 10.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) FAM176 PF14851.6 CDJ44505.1 - 0.088 12.5 16.1 0.062 13.0 6.6 2.2 2 0 0 2 2 2 0 FAM176 family EIIBC-GUT_N PF03612.14 CDJ44505.1 - 0.097 12.4 16.2 0.081 12.7 8.5 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3391 PF11871.8 CDJ44505.1 - 0.11 13.0 16.8 0.84 10.2 10.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4366 PF14283.6 CDJ44505.1 - 0.12 12.4 6.7 0.28 11.2 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF702 PF05142.12 CDJ44505.1 - 0.13 12.8 17.6 1.7 9.1 10.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) D123 PF07065.14 CDJ44505.1 - 0.13 11.4 10.8 0.065 12.4 5.0 2.1 2 0 0 2 2 2 0 D123 DcuA_DcuB PF03605.14 CDJ44505.1 - 0.14 11.1 4.6 0.064 12.1 0.8 2.0 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter Scs3p PF10261.9 CDJ44505.1 - 0.16 11.4 4.9 1.1 8.8 4.9 2.0 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM EPL1 PF10513.9 CDJ44505.1 - 0.18 12.2 19.9 2.9 8.3 13.7 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF1115 PF06544.12 CDJ44505.1 - 0.21 11.7 12.1 0.11 12.6 4.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) PRC2_HTH_1 PF18118.1 CDJ44505.1 - 0.21 12.4 12.7 3.8 8.4 9.5 2.1 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain DNApol_Exo PF18136.1 CDJ44505.1 - 0.23 10.6 13.7 0.17 11.0 7.9 2.0 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain DUF3464 PF11947.8 CDJ44505.1 - 0.24 11.1 21.0 0.51 10.1 13.4 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 TERB2 PF15101.6 CDJ44505.1 - 0.25 11.4 26.9 0.28 11.2 16.1 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF1178 PF06676.11 CDJ44505.1 - 0.28 11.6 17.1 3.8 7.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) DUF2052 PF09747.9 CDJ44505.1 - 0.3 11.2 21.6 0.067 13.3 9.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF3405 PF11885.8 CDJ44505.1 - 0.3 9.6 12.7 0.02 13.5 5.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3405) MMR1 PF08505.10 CDJ44505.1 - 0.31 11.3 21.2 0.14 12.4 11.3 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Spore_III_AF PF09581.10 CDJ44505.1 - 0.37 10.8 14.7 0.77 9.8 9.7 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) DUF5327 PF17261.2 CDJ44505.1 - 0.48 11.2 25.7 1.8 9.3 16.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Peptidase_S49_N PF08496.10 CDJ44505.1 - 0.54 10.3 17.0 2.3 8.3 10.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4628 PF15429.6 CDJ44505.1 - 0.55 9.9 13.4 0.15 11.8 5.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) TMEM144 PF07857.12 CDJ44505.1 - 0.57 9.1 2.7 0.28 10.1 0.4 1.6 2 0 0 2 2 2 0 Transmembrane family, TMEM144 of transporters MAS20 PF02064.15 CDJ44505.1 - 0.58 10.2 20.5 0.95 9.6 1.1 2.4 2 0 0 2 2 2 0 MAS20 protein import receptor BPL_N PF09825.9 CDJ44505.1 - 0.63 9.1 9.2 0.82 8.7 9.2 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF1980 PF09323.10 CDJ44505.1 - 0.75 9.7 15.0 0.11 12.4 6.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4746 PF15928.5 CDJ44505.1 - 0.76 9.1 12.7 0.26 10.6 5.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) PPL5 PF18168.1 CDJ44505.1 - 0.81 8.9 11.5 0.82 8.9 6.4 2.1 2 0 0 2 2 2 0 Prim-pol family 5 Tau95_N PF17682.1 CDJ44505.1 - 0.97 9.6 12.4 4.3 7.5 5.4 2.3 2 0 0 2 2 2 0 Tau95 Triple barrel domain TRM13 PF05206.14 CDJ44505.1 - 0.99 8.9 11.5 0.26 10.8 4.1 2.1 2 0 0 2 2 2 0 Methyltransferase TRM13 ORC_WH_C PF18137.1 CDJ44505.1 - 1 9.5 21.5 2.5 8.1 1.4 2.1 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Sporozoite_P67 PF05642.11 CDJ44505.1 - 1 7.4 7.8 9 4.2 5.0 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen eIF-3_zeta PF05091.12 CDJ44505.1 - 1.1 8.1 26.6 0.12 11.3 14.8 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CobT PF06213.12 CDJ44505.1 - 1.2 8.5 33.3 0.34 10.3 19.7 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT MMU163 PF17119.5 CDJ44505.1 - 1.2 8.3 9.1 0.34 10.0 4.0 2.0 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis CDK5_activator PF03261.15 CDJ44505.1 - 1.4 8.4 13.9 1.9 8.0 13.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein MPM1 PF17234.2 CDJ44505.1 - 1.4 9.1 21.3 5 7.4 12.7 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Folate_carrier PF01770.18 CDJ44505.1 - 1.5 7.5 12.5 0.15 10.7 5.6 2.0 2 0 0 2 2 2 0 Reduced folate carrier AIF_C PF14721.6 CDJ44505.1 - 1.5 9.2 15.9 3.5 8.0 9.3 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Dynamin_N PF00350.23 CDJ44505.1 - 1.5 8.8 7.6 0.44 10.6 2.4 2.0 2 0 0 2 2 2 0 Dynamin family Rxt3 PF08642.10 CDJ44505.1 - 1.5 9.6 11.4 2.7 8.8 5.6 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 INSIG PF07281.12 CDJ44505.1 - 1.6 8.4 10.4 3.2 7.4 5.7 2.6 2 1 0 2 2 2 0 Insulin-induced protein (INSIG) Tim54 PF11711.8 CDJ44505.1 - 1.6 7.4 18.3 1.8 7.2 11.5 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rbc25 PF08292.12 CDJ44505.1 - 1.6 8.9 14.7 3.4 7.9 7.2 2.4 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 FPN1 PF06963.12 CDJ44505.1 - 1.7 7.2 11.2 0.18 10.3 4.0 2.0 2 0 0 2 2 2 0 Ferroportin1 (FPN1) Maf1 PF09174.10 CDJ44505.1 - 1.7 8.8 10.6 12 6.0 0.1 2.1 2 0 0 2 2 2 0 Maf1 regulator Inhibitor_I71 PF12628.7 CDJ44505.1 - 1.7 8.5 6.8 3.4 7.5 2.6 2.1 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor DUF3506 PF12014.8 CDJ44505.1 - 2.1 8.4 9.4 1.9 8.5 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) DUF1644 PF07800.12 CDJ44505.1 - 2.1 8.4 10.8 2.6 8.1 5.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) DUF4820 PF16091.5 CDJ44505.1 - 2.2 7.6 18.0 0.21 10.9 6.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) TCP PF03634.13 CDJ44505.1 - 2.3 8.8 19.8 0.39 11.3 10.0 2.1 2 0 0 2 2 2 0 TCP family transcription factor TraV PF09676.10 CDJ44505.1 - 2.3 9.2 17.5 21 6.1 13.2 2.2 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Kei1 PF08552.11 CDJ44505.1 - 2.5 7.9 10.8 3.3 7.5 6.8 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 OATP PF03137.20 CDJ44505.1 - 2.6 6.2 14.9 0.0068 14.7 3.5 1.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Baculo_PP31 PF05311.11 CDJ44505.1 - 2.7 7.4 16.2 1 8.8 7.9 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) G0-G1_switch_2 PF15103.6 CDJ44505.1 - 3 8.3 20.3 3.1 8.3 11.8 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 RED_N PF07808.13 CDJ44505.1 - 3.4 7.2 23.3 2.6 7.5 14.1 2.1 2 0 0 2 2 2 0 RED-like protein N-terminal region DUF5352 PF17303.2 CDJ44505.1 - 3.5 7.5 8.9 3.9 7.3 2.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5352) RBM39linker PF15519.6 CDJ44505.1 - 3.6 8.7 18.3 6 8.0 1.3 2.5 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein MENTAL PF10457.9 CDJ44505.1 - 3.7 7.3 9.6 0.28 11.0 4.1 1.8 2 0 0 2 2 2 0 Cholesterol-capturing domain SAPS PF04499.15 CDJ44505.1 - 3.9 6.1 14.9 7.9 5.1 14.9 1.3 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein EFTUD2 PF16004.5 CDJ44505.1 - 4.1 8.0 23.2 10 6.8 0.5 2.1 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus NARP1 PF12569.8 CDJ44505.1 - 4.6 6.0 17.4 8.6 5.1 0.2 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 FixO PF02433.15 CDJ44505.1 - 4.7 6.6 12.1 1.7 8.1 6.0 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO CIAPIN1 PF05093.13 CDJ44505.1 - 4.8 7.7 13.2 7.4 7.1 0.3 2.5 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis SspB PF04386.13 CDJ44505.1 - 4.9 7.0 17.1 13 5.6 11.9 2.1 2 0 0 2 2 2 0 Stringent starvation protein B Paf1 PF03985.13 CDJ44505.1 - 5 6.0 27.0 0.16 11.0 13.2 2.0 2 0 0 2 2 2 0 Paf1 PBP1_TM PF14812.6 CDJ44505.1 - 5.1 7.6 12.3 32 5.0 0.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC2_membrane_2 PF12679.7 CDJ44505.1 - 5.2 6.3 8.1 0.29 10.4 2.3 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Serinc PF03348.15 CDJ44505.1 - 5.5 5.8 11.2 0.46 9.3 4.5 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) XAP5 PF04921.14 CDJ44505.1 - 5.7 6.7 14.8 21 4.8 10.4 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator Stig1 PF04885.13 CDJ44505.1 - 5.9 7.4 13.0 31 5.1 8.8 2.2 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 FHIPEP PF00771.20 CDJ44505.1 - 5.9 5.2 13.2 4.3 5.7 6.6 2.1 2 0 0 2 2 2 0 FHIPEP family BAT2_N PF07001.11 CDJ44505.1 - 6.8 7.1 20.7 8.3 6.8 0.6 2.2 2 0 0 2 2 2 0 BAT2 N-terminus U1snRNP70_N PF12220.8 CDJ44505.1 - 7.1 7.3 19.0 0.52 11.0 6.1 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PNISR PF15996.5 CDJ44505.1 - 7.2 6.8 26.5 3 8.1 13.7 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR TMEM51 PF15345.6 CDJ44505.1 - 7.5 6.3 25.4 0.92 9.3 11.7 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 DUF2072 PF09845.9 CDJ44505.1 - 7.6 6.8 14.7 8.3 6.7 8.1 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein Spo7 PF03907.13 CDJ44505.1 - 7.7 5.9 11.6 0.5 9.8 4.4 1.9 1 1 1 2 2 2 0 Spo7-like protein GOLD_2 PF13897.6 CDJ44505.1 - 7.9 7.0 7.4 11 6.6 2.6 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Orf78 PF06024.12 CDJ44505.1 - 8.1 6.8 13.1 13 6.2 8.0 2.3 2 0 0 2 2 2 0 Orf78 (ac78) dsRBD2 PF17842.1 CDJ44505.1 - 8.7 6.5 16.0 6.9 6.9 6.4 2.2 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 SID-1_RNA_chan PF13965.6 CDJ44505.1 - 8.8 4.6 10.4 0.23 9.8 3.4 1.7 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 tRNA_synt_1c_R2 PF04557.15 CDJ44505.1 - 9.4 7.2 16.5 36 5.4 10.3 2.3 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 CAF1 PF04857.20 CDJ44507.1 - 7.5e-08 31.9 0.0 8.6e-08 31.7 0.0 1.0 1 0 0 1 1 1 1 CAF1 family ribonuclease UQ_con PF00179.26 CDJ44508.1 - 7.3e-47 158.5 0.0 8.7e-47 158.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ44508.1 - 0.00025 20.7 0.0 0.0003 20.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ44508.1 - 0.0071 16.6 0.1 0.0078 16.5 0.1 1.3 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 CDJ44508.1 - 0.056 13.3 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain MIF4G_like PF09088.11 CDJ44510.1 - 0.0025 17.6 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 MIF4G like PRCC PF10253.9 CDJ44512.1 - 0.037 14.8 15.5 0.05 14.4 15.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting CCSAP PF15748.5 CDJ44512.1 - 0.86 9.7 10.5 1.2 9.3 10.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SprA-related PF12118.8 CDJ44512.1 - 0.94 8.6 19.9 1.2 8.2 19.9 1.1 1 0 0 1 1 1 0 SprA-related family RAB3GAP2_N PF14655.6 CDJ44512.1 - 0.96 8.6 5.2 1.3 8.2 5.2 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Hamartin PF04388.12 CDJ44512.1 - 2.3 6.8 10.2 2.6 6.6 10.2 1.1 1 0 0 1 1 1 0 Hamartin protein Med15 PF09606.10 CDJ44512.1 - 2.6 6.6 25.5 3 6.4 25.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.9 CDJ44512.1 - 9.6 4.3 17.8 11 4.1 17.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.7 CDJ44512.1 - 9.9 4.1 8.2 13 3.8 8.2 1.2 1 1 0 1 1 1 0 High-temperature-induced dauer-formation protein RXLR PF16810.5 CDJ44514.1 - 0.0025 18.2 5.4 0.003 18.0 5.4 1.1 1 0 0 1 1 1 1 RXLR phytopathogen effector protein, Avirulence activity DUF3824 PF12868.7 CDJ44514.1 - 0.014 16.0 2.2 0.014 16.0 2.2 2.1 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Lipase_GDSL PF00657.22 CDJ44514.1 - 0.041 13.9 3.6 0.047 13.6 3.6 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF3381 PF11861.8 CDJ44514.1 - 0.052 13.4 18.8 0.065 13.0 18.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF3391 PF11871.8 CDJ44514.1 - 0.33 11.5 12.2 0.38 11.3 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Spt20 PF12090.8 CDJ44514.1 - 0.41 10.2 22.5 0.47 10.0 22.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF2448 PF10476.9 CDJ44514.1 - 0.72 9.7 4.8 0.64 9.9 4.3 1.3 1 1 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) RskA PF10099.9 CDJ44514.1 - 0.74 10.1 10.6 1.1 9.5 10.6 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2232 PF09991.9 CDJ44514.1 - 1.1 8.3 1.9 1.8 7.7 1.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) HemX PF04375.14 CDJ44514.1 - 1.7 7.8 21.4 1.9 7.7 21.4 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2098 PF09871.9 CDJ44514.1 - 5.5 7.4 11.6 4.3 7.7 3.9 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Exonuc_VII_L PF02601.15 CDJ44514.1 - 6.6 6.2 13.4 7.4 6.0 13.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit U3_snoRNA_assoc PF08297.11 CDJ44514.1 - 7.5 7.3 15.4 6.2 7.6 2.4 2.1 2 0 0 2 2 2 0 U3 snoRNA associated K_channel_TID PF07941.11 CDJ44514.1 - 8 7.0 14.4 19 5.8 14.4 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DnaJ PF00226.31 CDJ44516.1 - 3.7e-11 43.0 0.0 4.8e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain LUC7 PF03194.15 CDJ44519.1 - 8e-28 97.8 0.2 8.6e-28 97.7 0.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Myb_DNA-binding PF00249.31 CDJ44520.1 - 5.5e-11 42.5 0.0 8.4e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 CDJ44520.1 - 2.4e-09 36.8 9.2 4.2e-09 36.1 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 CDJ44520.1 - 2.3e-06 27.8 0.0 3.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 CDJ44520.1 - 0.03 14.6 9.7 0.064 13.6 9.7 1.6 1 0 0 1 1 1 0 C1 domain IMUP PF15761.5 CDJ44520.1 - 0.21 12.3 17.4 0.087 13.5 7.4 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF2722 PF10846.8 CDJ44521.1 - 7e-05 22.0 0.7 0.0001 21.4 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ44521.1 - 0.016 15.9 5.3 0.016 15.9 5.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 CDJ44521.1 - 0.029 14.2 0.3 0.044 13.5 0.3 1.3 1 0 0 1 1 1 0 Connexin Pex26 PF07163.12 CDJ44521.1 - 0.033 13.5 3.4 0.067 12.5 3.4 1.5 1 0 0 1 1 1 0 Pex26 protein TFIIA PF03153.13 CDJ44521.1 - 0.039 13.9 12.8 0.061 13.3 12.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ephrin_rec_like PF07699.13 CDJ44521.1 - 0.083 12.7 0.2 0.083 12.7 0.2 4.0 3 1 1 4 4 4 0 Putative ephrin-receptor like Dsh_C PF12316.8 CDJ44521.1 - 0.11 13.0 17.6 2.3 8.5 13.9 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal CPSF100_C PF13299.6 CDJ44521.1 - 0.16 12.2 2.0 0.3 11.2 2.0 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CLN3 PF02487.17 CDJ44521.1 - 0.41 9.7 2.4 0.65 9.0 2.4 1.2 1 0 0 1 1 1 0 CLN3 protein DUF844 PF05815.11 CDJ44521.1 - 0.69 9.0 2.8 1.5 7.9 0.4 2.0 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF844) EIIBC-GUT_N PF03612.14 CDJ44521.1 - 3.6 7.3 7.2 6.5 6.5 7.2 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AIF_C PF14721.6 CDJ44521.1 - 5.2 7.4 6.3 12 6.2 6.3 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Spt20 PF12090.8 CDJ44521.1 - 5.6 6.5 20.4 11 5.6 20.4 1.4 1 0 0 1 1 1 0 Spt20 family Peptidase_S49_N PF08496.10 CDJ44521.1 - 6.4 6.8 8.1 16 5.6 8.1 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Laminin_EGF PF00053.24 CDJ44521.1 - 8.8 6.6 23.4 0.16 12.2 8.1 3.4 3 0 0 3 3 3 0 Laminin EGF domain GRAM PF02893.20 CDJ44523.1 - 7.9e-08 32.2 0.2 1e-07 31.8 0.2 1.1 1 0 0 1 1 1 1 GRAM domain LssY_C PF14067.6 CDJ44523.1 - 0.064 12.8 0.0 0.073 12.6 0.0 1.1 1 0 0 1 1 1 0 LssY C-terminus Activator_LAG-3 PF11498.8 CDJ44524.1 - 4.6 6.1 12.4 6.4 5.6 12.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 MPP6 PF10175.9 CDJ44525.1 - 1.5e-05 25.5 0.9 2.7e-05 24.7 0.9 1.5 1 1 0 1 1 1 1 M-phase phosphoprotein 6 K_channel_TID PF07941.11 CDJ44525.1 - 0.019 15.4 5.0 0.019 15.4 5.0 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain RskA PF10099.9 CDJ44525.1 - 2.3 8.5 12.1 3.9 7.7 12.1 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SART-1 PF03343.13 CDJ44526.1 - 4.2e-13 48.7 18.8 3e-12 45.9 18.8 1.9 1 1 0 1 1 1 1 SART-1 family THOC2_N PF16134.5 CDJ44526.1 - 0.072 11.7 5.6 0.077 11.6 5.6 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF966 PF06136.13 CDJ44526.1 - 0.61 9.8 8.2 0.67 9.6 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DASH_Spc19 PF08287.11 CDJ44526.1 - 0.96 9.3 8.7 4.3 7.2 8.7 2.1 1 1 0 1 1 1 0 Spc19 Med3 PF11593.8 CDJ44526.1 - 1.4 8.0 16.6 1.6 7.8 16.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MAGI_u5 PF16666.5 CDJ44526.1 - 4.8 7.4 11.3 7 6.8 10.8 1.5 1 1 0 1 1 1 0 Unstructured region on MAGI RNase_T PF00929.24 CDJ44527.1 - 0.063 13.8 0.0 0.069 13.7 0.0 1.2 1 0 0 1 1 1 0 Exonuclease ADH_N PF08240.12 CDJ44529.1 - 1.3e-11 44.3 0.1 1.7e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pkinase PF00069.25 CDJ44530.1 - 0.0023 17.3 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain FtsX PF02687.21 CDJ44533.1 - 0.016 15.6 5.2 0.022 15.2 2.9 2.1 2 0 0 2 2 2 0 FtsX-like permease family DUF1776 PF08643.10 CDJ44533.1 - 0.039 13.3 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) CD20 PF04103.15 CDJ44533.1 - 0.31 11.1 6.9 0.068 13.3 2.8 1.9 2 0 0 2 2 2 0 CD20-like family ParA PF10609.9 CDJ44535.1 - 7.3e-70 235.2 0.0 9.5e-70 234.8 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 CDJ44535.1 - 2.2e-11 44.0 0.0 5.4e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain CbiA PF01656.23 CDJ44535.1 - 2.3e-09 37.4 0.0 3.7e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 CDJ44535.1 - 8e-07 28.6 0.0 3.6e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CDJ44535.1 - 3.7e-05 23.1 0.1 9.4e-05 21.7 0.1 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 CDJ44535.1 - 8.3e-05 22.2 0.3 0.00058 19.4 0.1 2.2 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 CDJ44535.1 - 0.0019 18.1 0.1 0.0039 17.1 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 CDJ44535.1 - 0.0023 17.1 0.1 0.0035 16.6 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.6 CDJ44535.1 - 0.0024 17.5 0.1 0.0046 16.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ44535.1 - 0.0083 16.5 0.2 0.025 14.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 CDJ44535.1 - 0.0086 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 CDJ44535.1 - 0.031 14.2 0.1 0.064 13.1 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 CDJ44535.1 - 0.041 14.4 0.5 0.068 13.7 0.4 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ44535.1 - 0.045 13.0 0.1 0.073 12.3 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.15 CDJ44535.1 - 0.049 13.5 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 CDJ44535.1 - 0.096 12.6 0.4 0.24 11.3 0.2 1.7 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 CDJ44535.1 - 0.11 12.7 0.2 0.43 10.9 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_26 PF13500.6 CDJ44535.1 - 0.12 12.2 0.1 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CDJ44535.1 - 0.13 11.9 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 CDJ44535.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 CDJ44535.1 - 0.16 11.9 0.1 0.28 11.2 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KTI12 PF08433.10 CDJ44535.1 - 0.17 11.3 0.1 0.32 10.4 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 CDJ44535.1 - 0.17 11.9 0.6 12 6.1 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ribosomal_60s PF00428.19 CDJ44535.1 - 0.29 11.8 10.6 0.62 10.7 10.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein RNase_Zc3h12a PF11977.8 CDJ44536.1 - 1.1e-13 51.3 0.0 2.6e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Ribosomal_60s PF00428.19 CDJ44537.1 - 0.21 12.2 8.8 0.26 11.9 8.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Dehydrin PF00257.19 CDJ44537.1 - 1.7 9.2 11.9 0.092 13.3 2.1 2.1 2 0 0 2 2 2 0 Dehydrin HEAT PF02985.22 CDJ44538.1 - 1.9e-05 24.5 2.6 0.068 13.5 0.1 4.6 4 0 0 4 4 4 2 HEAT repeat LpxC PF03331.13 CDJ44538.1 - 0.0019 17.8 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase HEAT_2 PF13646.6 CDJ44538.1 - 0.0045 17.4 9.7 0.032 14.6 0.3 3.5 2 2 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 CDJ44538.1 - 0.0087 16.5 11.5 0.68 10.5 0.1 4.2 3 1 1 4 4 4 2 HEAT-like repeat RTP1_C1 PF10363.9 CDJ44538.1 - 0.016 15.4 0.1 1.5 9.0 0.0 2.8 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 CDJ44538.1 - 0.02 14.0 0.4 0.082 12.0 0.2 2.0 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal Arm PF00514.23 CDJ44538.1 - 0.073 13.1 2.1 0.49 10.5 0.3 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat IMUP PF15761.5 CDJ44538.1 - 0.28 11.9 8.0 0.78 10.4 8.0 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein STI1 PF17830.1 CDJ44539.1 - 0.0021 17.9 4.1 0.0021 17.9 4.1 3.5 4 0 0 4 4 4 1 STI1 domain DUF2722 PF10846.8 CDJ44539.1 - 0.0042 16.1 0.8 0.0042 16.1 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Roughex PF06020.11 CDJ44539.1 - 0.0076 15.4 1.1 0.0091 15.1 1.1 1.1 1 0 0 1 1 1 1 Drosophila roughex protein SUIM_assoc PF16619.5 CDJ44539.1 - 0.013 15.6 13.1 0.023 14.8 13.1 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 ubiquitin PF00240.23 CDJ44539.1 - 0.095 12.5 0.1 0.095 12.5 0.1 1.6 2 0 0 2 2 2 0 Ubiquitin family Spt20 PF12090.8 CDJ44539.1 - 0.16 11.5 9.5 0.23 11.0 9.5 1.2 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 CDJ44539.1 - 0.25 10.5 22.6 0.31 10.2 22.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2967 PF11179.8 CDJ44539.1 - 0.4 8.7 4.8 0.48 8.5 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) RAB3GAP2_N PF14655.6 CDJ44539.1 - 1.7 7.8 4.1 2.4 7.3 4.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus GerD PF17898.1 CDJ44539.1 - 2.8 7.9 12.1 0.15 12.0 5.7 2.1 2 1 0 2 2 2 0 Spore germination GerD central core domain DUF3306 PF11748.8 CDJ44542.1 - 3 8.7 13.1 0.5 11.2 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) F-box-like PF12937.7 CDJ44544.1 - 1.7e-06 27.8 3.9 0.022 14.6 0.1 2.4 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 CDJ44544.1 - 0.01 15.7 0.2 2.3 8.2 0.1 2.3 2 0 0 2 2 2 0 F-box domain F-box_5 PF18511.1 CDJ44544.1 - 0.18 11.4 1.8 4.3 7.0 0.2 2.3 2 0 0 2 2 2 0 F-box Methyltransf_16 PF10294.9 CDJ44545.1 - 6.9e-18 65.0 0.0 5.9e-16 58.7 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CDJ44545.1 - 1e-07 31.9 0.0 1.3e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ44545.1 - 2.5e-05 24.9 0.0 4.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ44545.1 - 7e-05 22.4 0.2 0.00067 19.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CDJ44545.1 - 0.0014 19.3 0.5 0.049 14.3 0.1 2.4 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CDJ44545.1 - 0.0092 15.4 0.0 0.0092 15.4 0.0 1.6 2 0 0 2 2 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CDJ44545.1 - 0.013 15.3 1.3 0.045 13.6 1.3 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF2722 PF10846.8 CDJ44545.1 - 0.016 14.2 1.6 0.018 14.1 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ44545.1 - 0.03 13.9 8.5 0.043 13.4 8.5 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ44545.1 - 0.056 13.5 6.4 0.066 13.2 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Clr2 PF10383.9 CDJ44545.1 - 0.072 13.9 0.2 0.11 13.3 0.2 1.3 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 Activator_LAG-3 PF11498.8 CDJ44545.1 - 3.2 6.6 17.3 4.7 6.1 17.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RskA PF10099.9 CDJ44545.1 - 9.9 6.4 15.4 2.4e+02 1.9 15.4 2.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ44546.1 - 0.006 16.6 45.6 0.01 15.9 45.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SMYLE_N PF18615.1 CDJ44546.1 - 0.031 13.9 20.0 0.044 13.4 20.0 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF966 PF06136.13 CDJ44546.1 - 0.071 12.8 21.9 0.089 12.5 21.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Utp14 PF04615.13 CDJ44546.1 - 1.2 7.6 28.3 1.5 7.3 28.3 1.0 1 0 0 1 1 1 0 Utp14 protein DZR PF12773.7 CDJ44546.1 - 1.5 8.9 5.5 0.36 10.9 1.5 2.0 2 0 0 2 2 2 0 Double zinc ribbon Hamartin PF04388.12 CDJ44546.1 - 4.6 5.8 22.7 5.6 5.5 22.7 1.1 1 0 0 1 1 1 0 Hamartin protein SOBP PF15279.6 CDJ44546.1 - 5.4 7.5 21.6 7.4 7.1 21.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Med15 PF09606.10 CDJ44546.1 - 9.1 4.8 47.9 12 4.4 47.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ44547.1 - 0.073 12.7 7.9 0.067 12.8 7.9 1.1 1 0 0 1 1 1 0 Spt20 family DUF5421 PF17458.2 CDJ44547.1 - 2 7.7 8.7 2.2 7.6 8.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Tubulin_C PF03953.17 CDJ44549.1 - 2.4e-14 53.6 0.0 3.7e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF3275 PF11679.8 CDJ44552.1 - 9.2 6.2 7.5 12 5.8 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) V_ATPase_I PF01496.19 CDJ44553.1 - 2.9 5.7 13.0 3.2 5.5 13.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_7 PF12775.7 CDJ44554.1 - 7.3e-36 123.4 0.0 9.9e-36 122.9 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 CDJ44554.1 - 1.8e-08 35.0 0.5 2e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDJ44554.1 - 1.8e-07 31.5 0.0 4.5e-07 30.2 0.0 1.6 2 0 0 2 2 1 1 AAA domain Dynein_AAA_lid PF17852.1 CDJ44554.1 - 3.5e-06 27.1 0.1 6.5e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CDJ44554.1 - 2.2e-05 24.9 0.0 4.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CDJ44554.1 - 2.9e-05 23.3 0.1 4.7e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 CDJ44554.1 - 3.4e-05 24.0 0.0 5.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 CDJ44554.1 - 5.1e-05 23.1 0.0 7.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain ATPase_2 PF01637.18 CDJ44554.1 - 7.4e-05 22.8 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea cobW PF02492.19 CDJ44554.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 CDJ44554.1 - 0.00019 21.4 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 CDJ44554.1 - 0.00055 20.1 1.1 0.00073 19.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 CDJ44554.1 - 0.00068 20.2 0.0 0.0011 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CDJ44554.1 - 0.0012 18.8 0.1 0.002 18.0 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase TsaE PF02367.17 CDJ44554.1 - 0.0013 18.7 0.1 0.0022 18.0 0.1 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Guanylate_kin PF00625.21 CDJ44554.1 - 0.0014 18.4 0.1 0.0024 17.6 0.1 1.3 1 0 0 1 1 1 1 Guanylate kinase AAA_29 PF13555.6 CDJ44554.1 - 0.0015 18.2 0.1 0.0034 17.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.6 CDJ44554.1 - 0.0021 18.1 0.0 0.0032 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ44554.1 - 0.0021 17.8 0.0 0.0021 17.8 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 CDJ44554.1 - 0.0035 17.4 0.1 0.0063 16.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CDJ44554.1 - 0.0057 16.9 0.6 0.024 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 CDJ44554.1 - 0.0059 15.6 0.0 0.0099 14.8 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 CDJ44554.1 - 0.0076 16.8 0.0 0.013 16.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SRPRB PF09439.10 CDJ44554.1 - 0.011 15.2 0.1 0.017 14.6 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 CDJ44554.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.6 CDJ44554.1 - 0.015 15.6 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDJ44554.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CDJ44554.1 - 0.02 14.8 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 CDJ44554.1 - 0.025 13.8 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Septin PF00735.18 CDJ44554.1 - 0.026 13.8 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 Septin Viral_helicase1 PF01443.18 CDJ44554.1 - 0.034 13.9 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CDJ44554.1 - 0.053 13.3 0.1 0.095 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 CDJ44554.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 CDJ44554.1 - 0.057 12.6 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF815 PF05673.13 CDJ44554.1 - 0.068 12.3 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Roc PF08477.13 CDJ44554.1 - 0.075 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 CDJ44554.1 - 0.079 13.4 0.6 0.13 12.8 0.3 1.4 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 CDJ44554.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain G-alpha PF00503.20 CDJ44554.1 - 0.099 11.8 0.4 0.13 11.4 0.4 1.1 1 0 0 1 1 1 0 G-protein alpha subunit RNA_helicase PF00910.22 CDJ44554.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 CDJ44554.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 CDJ44554.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.18 CDJ44554.1 - 0.24 11.1 0.0 1.4 8.6 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SR-25 PF10500.9 CDJ44555.1 - 2.6 7.6 5.4 3 7.4 5.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hus1 PF04005.12 CDJ44558.1 - 5e-12 45.5 0.0 5.6e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein HEAT PF02985.22 CDJ44559.1 - 0.027 14.7 0.1 0.027 14.7 0.1 2.3 3 1 0 3 3 3 0 HEAT repeat Spt20 PF12090.8 CDJ44560.1 - 0.041 13.5 14.8 0.036 13.7 14.8 1.0 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 CDJ44560.1 - 0.16 11.2 10.2 0.15 11.2 10.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4834 PF16118.5 CDJ44560.1 - 0.4 11.7 4.8 0.39 11.7 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 CDJ44560.1 - 1.5 7.6 15.1 1.4 7.7 15.1 1.0 1 0 0 1 1 1 0 Androgen receptor DUF2722 PF10846.8 CDJ44560.1 - 1.7 7.5 14.0 1.7 7.5 14.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2967 PF11179.8 CDJ44560.1 - 2 6.4 9.5 1.9 6.5 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) PgaD PF13994.6 CDJ44561.1 - 0.39 10.8 0.1 0.39 10.8 0.1 2.7 3 0 0 3 3 3 0 PgaD-like protein LMBR1 PF04791.16 CDJ44561.1 - 2.6 6.8 3.5 2.8 6.8 3.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SR-25 PF10500.9 CDJ44562.1 - 0.0038 16.9 16.8 0.0038 16.9 16.8 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CSRNP_N PF16019.5 CDJ44562.1 - 0.012 15.5 3.3 0.014 15.4 3.3 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Nop25 PF09805.9 CDJ44562.1 - 0.016 15.7 0.8 0.016 15.7 0.8 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SKA1 PF07160.12 CDJ44562.1 - 0.52 10.1 5.2 0.52 10.1 5.2 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 TFIIA PF03153.13 CDJ44562.1 - 0.54 10.2 10.9 0.56 10.1 10.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Vasculin PF15337.6 CDJ44562.1 - 0.66 10.9 14.2 0.59 11.0 10.4 2.1 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 DUF755 PF05501.11 CDJ44562.1 - 1.4 9.3 43.7 0.098 12.9 2.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF755) Lin-8 PF03353.15 CDJ44562.1 - 1.6 8.3 15.8 0.021 14.4 8.9 1.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Spt20 PF12090.8 CDJ44562.1 - 2.3 7.8 12.2 3.2 7.3 12.2 1.2 1 0 0 1 1 1 0 Spt20 family GREB1 PF15782.5 CDJ44562.1 - 3.4 4.7 11.3 3.1 4.8 11.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3446 PF11928.8 CDJ44562.1 - 4.8 7.5 25.2 6.7 7.1 1.9 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain SPX PF03105.19 CDJ44562.1 - 5.5 6.8 15.6 6.3 6.6 15.6 1.0 1 0 0 1 1 1 0 SPX domain TraG_N PF07916.11 CDJ44563.1 - 0.52 9.1 9.4 0.62 8.8 9.4 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Raftlin PF15250.6 CDJ44563.1 - 3.4 6.3 8.2 3.9 6.1 8.2 1.1 1 0 0 1 1 1 0 Raftlin ACC_epsilon PF13822.6 CDJ44564.1 - 0.0074 16.9 2.2 0.0074 16.9 2.2 10.4 8 2 2 10 10 10 1 Acyl-CoA carboxylase epsilon subunit UFD1 PF03152.14 CDJ44565.1 - 3.1e-47 160.3 0.0 4e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Apt1 PF10351.9 CDJ44565.1 - 0.065 12.1 5.9 0.073 11.9 5.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MAP17 PF15807.5 CDJ44566.1 - 0.011 16.0 4.7 0.018 15.3 0.1 2.3 1 1 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2127 PF09900.9 CDJ44566.1 - 0.36 11.1 5.1 0.35 11.1 3.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2127) DUF4865 PF16157.5 CDJ44566.1 - 0.44 10.5 4.7 0.28 11.2 2.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4865) RNB PF00773.19 CDJ44568.1 - 2.3e-66 224.4 0.4 2.3e-66 224.4 0.4 3.5 3 1 0 3 3 3 1 RNB domain OB_Dis3 PF17849.1 CDJ44568.1 - 7.5e-11 41.9 0.0 2.4e-10 40.3 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 CDJ44568.1 - 0.14 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Cold shock domain Ebp2 PF05890.12 CDJ44569.1 - 2.6e-07 30.5 0.2 3.8e-07 30.0 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Radical_SAM PF04055.21 CDJ44570.1 - 3.4e-05 24.3 0.0 0.0015 18.9 0.0 2.1 1 1 0 1 1 1 1 Radical SAM superfamily BKACE PF05853.12 CDJ44570.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme TFIIA PF03153.13 CDJ44571.1 - 0.00047 20.3 28.0 0.00082 19.5 28.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Peroxin-3 PF04882.12 CDJ44571.1 - 0.0027 16.8 4.4 0.0027 16.8 4.4 2.0 2 0 0 2 2 2 1 Peroxin-3 CLN3 PF02487.17 CDJ44571.1 - 0.0084 15.2 1.0 0.014 14.4 1.0 1.4 1 0 0 1 1 1 1 CLN3 protein DUF2126 PF09899.9 CDJ44571.1 - 0.12 10.4 8.0 0.17 10.0 8.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) BAF1_ABF1 PF04684.13 CDJ44571.1 - 0.29 10.1 11.2 0.41 9.7 11.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SLC12 PF03522.15 CDJ44571.1 - 0.42 9.6 8.0 0.62 9.0 8.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Folate_carrier PF01770.18 CDJ44571.1 - 0.79 8.4 5.9 6.6 5.3 3.2 2.1 2 0 0 2 2 2 0 Reduced folate carrier V_ATPase_I PF01496.19 CDJ44571.1 - 0.8 7.5 8.4 1.1 7.0 8.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AUX_IAA PF02309.16 CDJ44571.1 - 0.88 9.4 6.4 1.4 8.7 6.4 1.3 1 0 0 1 1 1 0 AUX/IAA family DUF5427 PF10310.9 CDJ44571.1 - 1.2 8.1 20.0 2.3 7.1 20.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Membralin PF09746.9 CDJ44571.1 - 1.2 8.1 3.2 1.9 7.4 3.2 1.3 1 0 0 1 1 1 0 Tumour-associated protein DUF4746 PF15928.5 CDJ44571.1 - 1.7 8.0 10.0 2.6 7.4 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Ribosomal_60s PF00428.19 CDJ44571.1 - 2.2 8.9 19.9 0.17 12.5 7.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein SARAF PF06682.12 CDJ44571.1 - 2.4 7.7 21.6 3.8 7.1 21.2 1.5 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Dicty_REP PF05086.12 CDJ44571.1 - 3.9 5.3 9.0 5.2 4.9 9.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleo_P87 PF07267.11 CDJ44571.1 - 4.9 5.9 16.9 6.4 5.5 16.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SKA1 PF07160.12 CDJ44571.1 - 5.6 6.7 12.6 11 5.8 12.6 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Plasmodium_Vir PF05795.11 CDJ44571.1 - 6.3 6.1 7.1 9.3 5.6 7.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PepSY_TM_like_2 PF16357.5 CDJ44571.1 - 6.5 6.7 7.1 10 6.0 7.1 1.2 1 0 0 1 1 1 0 Putative PepSY_TM-like PAT1 PF09770.9 CDJ44571.1 - 8.5 4.5 29.0 11 4.1 29.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Alpha-amylase PF00128.24 CDJ44572.1 - 8e-08 32.2 0.0 1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Ribosomal_60s PF00428.19 CDJ44572.1 - 0.67 10.6 10.7 2.5 8.7 10.3 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF5427 PF10310.9 CDJ44575.1 - 1.1 8.2 7.4 1.7 7.5 7.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Apt1 PF10351.9 CDJ44575.1 - 1.6 7.5 7.7 2.1 7.1 7.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CAF1C_H4-bd PF12265.8 CDJ44578.1 - 9.7e-21 73.8 0.2 1.5e-20 73.2 0.2 1.3 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex CCDC24 PF15669.5 CDJ44578.1 - 5.1 6.9 5.4 7.8 6.3 5.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family SR-25 PF10500.9 CDJ44578.1 - 5.2 6.6 13.2 7.7 6.1 13.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Alpha_adaptinC2 PF02883.20 CDJ44582.1 - 0.00061 20.1 0.6 0.0015 18.8 0.6 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Peripla_BP_1 PF00532.21 CDJ44582.1 - 0.032 13.7 0.2 0.07 12.5 0.2 1.5 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Macoilin PF09726.9 CDJ44582.1 - 0.092 11.3 11.2 0.17 10.4 11.2 1.5 1 0 0 1 1 1 0 Macoilin family DDE_Tnp_IS66_C PF13817.6 CDJ44582.1 - 0.12 12.6 0.1 30 4.9 0.0 2.7 2 0 0 2 2 2 0 IS66 C-terminal element SPX PF03105.19 CDJ44582.1 - 0.18 11.7 18.8 0.31 10.9 18.8 1.3 1 0 0 1 1 1 0 SPX domain DUF572 PF04502.13 CDJ44582.1 - 1.9 8.0 5.5 2.9 7.4 5.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.9 CDJ44582.1 - 1.9 7.2 16.9 3 6.6 16.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peroxin-3 PF04882.12 CDJ44582.1 - 3.4 6.6 11.2 6.1 5.7 11.2 1.4 1 0 0 1 1 1 0 Peroxin-3 DUF3292 PF11696.8 CDJ44582.1 - 3.7 5.8 7.3 0.77 8.1 3.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) SOBP PF15279.6 CDJ44582.1 - 8.4 6.9 9.7 17 5.9 9.7 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein PhoLip_ATPase_C PF16212.5 CDJ44583.1 - 5.7e-29 101.6 9.3 9.2e-29 100.9 9.3 1.3 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 CDJ44583.1 - 3.8e-11 43.7 5.6 5.5e-06 26.8 0.1 2.8 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ44583.1 - 4.8e-05 23.2 0.1 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDJ44583.1 - 0.16 12.1 0.0 0.79 9.9 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SR-25 PF10500.9 CDJ44584.1 - 0.17 11.4 18.1 0.2 11.2 18.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YABBY PF04690.13 CDJ44584.1 - 0.72 10.4 15.7 0.77 10.3 15.7 1.0 1 0 0 1 1 1 0 YABBY protein IL1_propep PF02394.16 CDJ44584.1 - 0.93 10.5 6.8 1 10.3 6.8 1.1 1 0 0 1 1 1 0 Interleukin-1 propeptide SMYLE_N PF18615.1 CDJ44584.1 - 7.9 5.9 15.7 8.9 5.8 15.7 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Ureide_permease PF07168.11 CDJ44584.1 - 9.9 4.8 7.3 10 4.8 7.3 1.0 1 0 0 1 1 1 0 Ureide permease Helicase_C PF00271.31 CDJ44585.1 - 2.5e-14 53.5 0.2 1.2e-13 51.4 0.0 2.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CDJ44585.1 - 4.3e-12 46.1 0.2 5.4e-11 42.6 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) DUF5539 PF17693.1 CDJ44585.1 - 0.002 17.8 4.8 0.0028 17.3 4.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5539) CLN3 PF02487.17 CDJ44585.1 - 0.37 9.8 4.3 0.53 9.3 4.3 1.3 1 0 0 1 1 1 0 CLN3 protein TAF4 PF05236.14 CDJ44585.1 - 4 7.1 23.2 7.3 6.2 22.7 1.8 2 1 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family CLP_protease PF00574.23 CDJ44586.1 - 1.3e-05 25.1 1.5 0.004 17.1 0.4 2.3 2 1 0 2 2 2 2 Clp protease DUF4781 PF16013.5 CDJ44586.1 - 0.48 9.2 3.6 0.3 9.9 1.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4781) Tic110 PF16940.5 CDJ44586.1 - 3.6 5.9 5.2 4.7 5.6 5.2 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter Lon_C PF05362.13 CDJ44587.1 - 2.5e-64 216.6 0.0 1.7e-63 213.9 0.0 1.9 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 CDJ44587.1 - 4.1e-07 29.9 0.0 5.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase DUF2228 PF10228.9 CDJ44588.1 - 0.059 13.1 0.0 0.55 9.9 0.0 2.3 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) RskA PF10099.9 CDJ44588.1 - 0.37 11.1 31.5 0.032 14.5 18.2 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA 2OG-FeII_Oxy_5 PF13759.6 CDJ44588.1 - 0.37 11.2 2.1 0.93 9.9 0.0 2.2 2 1 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Spt20 PF12090.8 CDJ44588.1 - 2 8.0 9.6 0.14 11.7 4.0 1.9 2 0 0 2 2 2 0 Spt20 family Med3 PF11593.8 CDJ44588.1 - 2.9 7.0 31.8 0.023 13.9 21.3 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF2514 PF10721.9 CDJ44589.1 - 0.021 14.9 0.5 0.026 14.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) ELL PF10390.9 CDJ44589.1 - 0.065 12.7 0.0 0.073 12.6 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL SAPS PF04499.15 CDJ44590.1 - 0.26 10.0 1.3 0.41 9.4 1.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UTP15_C PF09384.10 CDJ44591.1 - 1.2e-09 38.0 0.3 1.4e-09 37.8 0.3 1.0 1 0 0 1 1 1 1 UTP15 C terminal Utp12 PF04003.12 CDJ44591.1 - 0.0047 17.2 0.3 0.0052 17.1 0.3 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family UPF0565 PF10561.9 CDJ44592.1 - 0.05 12.8 5.1 0.047 12.9 5.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Mcm10 PF09332.11 CDJ44592.1 - 0.27 10.6 18.1 0.3 10.5 18.1 1.2 1 0 0 1 1 1 0 Mcm10 replication factor V_ATPase_I PF01496.19 CDJ44592.1 - 0.99 7.2 14.7 1 7.2 14.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDHD PF02862.17 CDJ44592.1 - 1.4 9.0 12.3 1.7 8.8 12.3 1.3 1 0 0 1 1 1 0 DDHD domain MMR1 PF08505.10 CDJ44592.1 - 1.5 9.1 20.8 1.8 8.8 20.8 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4175 PF13779.6 CDJ44592.1 - 2.4 5.9 37.1 2.7 5.8 37.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FAM91_C PF14648.6 CDJ44592.1 - 2.5 6.8 9.9 2.7 6.7 9.9 1.1 1 0 0 1 1 1 0 FAM91 C-terminus DUF572 PF04502.13 CDJ44592.1 - 3.1 7.4 16.8 3.2 7.3 16.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Presenilin PF01080.17 CDJ44592.1 - 3.6 6.2 17.1 3.6 6.2 17.1 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ44592.1 - 4.4 7.3 13.9 5.1 7.1 13.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BAF1_ABF1 PF04684.13 CDJ44592.1 - 4.7 6.2 17.6 4.7 6.1 17.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Surface_antigen PF11054.8 CDJ44593.1 - 4.5e-18 65.8 0.0 5e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ44594.1 - 5.1e-81 271.9 4.3 5.9e-81 271.7 4.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen RBFA PF02033.18 CDJ44595.1 - 2.2e-06 28.1 2.0 9e-06 26.1 0.0 2.5 2 1 1 3 3 3 1 Ribosome-binding factor A Macoilin PF09726.9 CDJ44595.1 - 0.025 13.1 14.4 0.034 12.7 14.4 1.1 1 0 0 1 1 1 0 Macoilin family PPP4R2 PF09184.11 CDJ44595.1 - 1.1 8.8 8.7 0.19 11.3 4.2 1.9 2 0 0 2 2 2 0 PPP4R2 Apt1 PF10351.9 CDJ44595.1 - 8 5.2 19.1 0.5 9.2 12.2 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain BAF1_ABF1 PF04684.13 CDJ44596.1 - 0.085 11.9 6.1 0.097 11.7 6.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RskA PF10099.9 CDJ44596.1 - 0.21 11.8 12.1 0.26 11.6 12.1 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CDK2AP PF09806.9 CDJ44596.1 - 0.24 11.4 15.9 0.33 11.0 15.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein eIF3_subunit PF08597.10 CDJ44596.1 - 0.64 9.9 13.7 0.78 9.6 13.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Med3 PF11593.8 CDJ44596.1 - 0.78 8.9 15.2 0.85 8.7 15.2 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 CDJ44596.1 - 0.85 9.5 17.4 0.93 9.4 17.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GET2 PF08690.10 CDJ44596.1 - 0.86 9.2 9.0 1 8.9 9.0 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 DOR PF14839.6 CDJ44596.1 - 1.6 8.7 10.5 1.8 8.4 10.5 1.1 1 0 0 1 1 1 0 DOR family MAJIN PF15077.6 CDJ44596.1 - 2 8.1 8.3 2.5 7.8 8.3 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Dsh_C PF12316.8 CDJ44596.1 - 4.5 7.6 14.8 5.9 7.2 14.8 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RR_TM4-6 PF06459.12 CDJ44596.1 - 8.7 6.1 10.6 9.8 5.9 10.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 OmpH PF03938.14 CDJ44596.1 - 9.7 6.5 22.9 12 6.2 22.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Activator_LAG-3 PF11498.8 CDJ44597.1 - 0.00062 18.9 21.3 0.00076 18.6 21.3 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Ribosomal_60s PF00428.19 CDJ44597.1 - 0.2 12.3 9.7 0.22 12.1 0.8 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein TERB2 PF15101.6 CDJ44597.1 - 0.53 10.3 12.0 0.51 10.4 9.7 1.9 2 0 0 2 2 2 0 Telomere-associated protein TERB2 TFIIA PF03153.13 CDJ44597.1 - 0.74 9.8 18.9 0.8 9.6 18.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_UL32 PF06070.11 CDJ44597.1 - 0.77 7.4 10.8 0.82 7.3 10.8 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 RskA PF10099.9 CDJ44597.1 - 1.6 9.0 20.3 4.4 7.6 20.3 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DivIC PF04977.15 CDJ44597.1 - 5.7 6.8 14.2 3.3 7.5 12.4 1.5 1 1 0 1 1 1 0 Septum formation initiator TFIIA PF03153.13 CDJ44598.1 - 0.014 15.4 10.6 0.016 15.2 10.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ44598.1 - 4.2 6.9 17.9 5.7 6.5 17.9 1.2 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 CDJ44600.1 - 0.031 13.0 1.0 0.041 12.6 1.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SpoIIP PF07454.11 CDJ44600.1 - 1 8.7 7.0 1.3 8.5 7.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 CDJ44600.1 - 1.3 8.9 23.1 1.5 8.7 23.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 CDJ44600.1 - 2.1 8.6 12.3 2.8 8.2 12.3 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PAT1 PF09770.9 CDJ44600.1 - 3.5 5.8 15.6 4 5.6 15.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 XRCC4 PF06632.12 CDJ44600.1 - 6.6 5.5 12.8 9.1 5.0 12.8 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Presenilin PF01080.17 CDJ44600.1 - 7 5.3 11.7 12 4.6 11.7 1.4 1 0 0 1 1 1 0 Presenilin CH_2 PF06294.11 CDJ44601.1 - 3.3e-18 65.6 0.3 8.3e-18 64.3 0.0 1.8 2 0 0 2 2 2 1 CH-like domain in sperm protein DUF3972 PF13118.6 CDJ44601.1 - 0.02 15.3 7.6 0.1 13.0 7.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) CAMSAP_CH PF11971.8 CDJ44601.1 - 0.036 13.9 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain Orbi_VP5 PF00901.17 CDJ44601.1 - 0.14 10.5 0.2 0.23 9.8 0.2 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 zf-Mss51 PF13824.6 CDJ44601.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 AP1AR PF15745.5 CDJ44601.1 - 0.43 10.2 2.8 0.28 10.8 1.1 1.5 1 1 0 1 1 1 0 AP-1 complex-associated regulatory protein OAD_gamma PF04277.13 CDJ44602.1 - 0.021 15.4 2.9 0.071 13.7 2.9 2.0 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Pkinase_Tyr PF07714.17 CDJ44603.1 - 0.0026 17.1 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SR-25 PF10500.9 CDJ44603.1 - 0.044 13.4 1.9 0.079 12.6 1.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EDR1 PF14381.6 CDJ44603.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Pkinase PF00069.25 CDJ44603.1 - 0.11 11.8 0.0 4.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain Med3 PF11593.8 CDJ44603.1 - 0.15 11.2 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DnaJ PF00226.31 CDJ44604.1 - 4.8e-06 26.6 0.0 5.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CDJ44604.1 - 2.5e-05 24.3 0.0 2.8e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Pam16 Calsarcin PF05556.11 CDJ44605.1 - 0.011 15.3 0.6 0.012 15.2 0.6 1.0 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) Spt20 PF12090.8 CDJ44605.1 - 2 8.0 9.7 1.9 8.0 9.7 1.1 1 0 0 1 1 1 0 Spt20 family PUNUT PF16913.5 CDJ44606.1 - 0.08 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport Pkinase PF00069.25 CDJ44607.1 - 8.6e-06 25.3 2.5 0.0079 15.6 0.0 3.7 4 0 0 4 4 4 3 Protein kinase domain tRNA_U5-meth_tr PF05958.11 CDJ44609.1 - 5.8e-11 42.0 0.1 2.4e-10 40.0 0.1 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CDJ44609.1 - 1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CDJ44609.1 - 0.00015 21.5 0.1 0.00032 20.4 0.1 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PCMT PF01135.19 CDJ44609.1 - 0.0022 17.8 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CDJ44609.1 - 0.0031 18.2 2.6 0.0057 17.3 0.6 2.4 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CDJ44609.1 - 0.021 15.8 0.4 0.17 13.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 CDJ44609.1 - 0.032 13.8 0.5 1.2 8.6 0.5 2.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 CDJ44609.1 - 0.13 11.8 0.1 0.75 9.3 0.1 2.2 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 CDJ44609.1 - 0.24 10.7 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF1635 PF07795.11 CDJ44609.1 - 1.1 9.1 3.6 11 5.8 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) CCDC24 PF15669.5 CDJ44609.1 - 1.3 8.9 7.0 7.6 6.3 5.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family GCP_C_terminal PF04130.13 CDJ44611.1 - 9.1e-19 68.0 0.8 1.3e-18 67.5 0.8 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Tox-WTIP PF15654.6 CDJ44611.1 - 0.38 11.2 0.0 0.38 11.2 0.0 2.3 3 0 0 3 3 3 0 Toxin with a conserved tryptophan and TIP tripeptide motif TFIIA PF03153.13 CDJ44611.1 - 1.8 8.5 20.7 2.9 7.8 20.7 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ubiquitin PF00240.23 CDJ44612.1 - 1.6e-16 59.8 0.3 3.7e-16 58.6 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CDJ44612.1 - 1.8e-11 43.7 0.2 5.7e-11 42.1 0.2 2.0 1 0 0 1 1 1 1 UBA/TS-N domain DUF2407 PF10302.9 CDJ44612.1 - 0.00047 20.7 5.3 0.00047 20.7 2.4 2.3 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ44612.1 - 0.0013 18.8 0.0 0.0013 18.8 0.0 3.0 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 CDJ44612.1 - 0.0014 18.4 0.1 0.0014 18.4 0.1 1.9 2 0 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CDJ44612.1 - 0.0085 16.0 0.0 0.0085 16.0 0.0 1.7 2 0 0 2 2 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 CDJ44612.1 - 0.022 14.8 0.0 0.022 14.8 0.0 2.3 2 1 1 3 3 3 0 Ubiquitin-like domain RskA PF10099.9 CDJ44612.1 - 0.088 13.1 44.6 0.44 10.8 10.9 2.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ44612.1 - 0.29 10.7 19.4 0.3 10.7 4.4 2.3 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 CDJ44612.1 - 1.7 8.8 28.6 0.19 11.8 5.0 2.6 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Suf PF05843.14 CDJ44612.1 - 3.9 7.4 10.8 0.23 11.4 2.7 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) CAP_N PF01213.19 CDJ44612.1 - 4.4 6.7 17.7 0.69 9.3 12.4 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Med15 PF09606.10 CDJ44612.1 - 6.4 5.3 30.6 2.1 6.9 6.0 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal TBCA PF02970.16 CDJ44613.1 - 6.9e-15 55.2 8.9 6.9e-15 55.2 8.9 2.4 1 1 1 2 2 2 1 Tubulin binding cofactor A SUIM_assoc PF16619.5 CDJ44613.1 - 0.19 11.8 24.4 0.41 10.7 3.3 3.1 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ44613.1 - 2.6 7.9 19.0 3.5 7.5 19.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDE_Tnp_1_2 PF13586.6 CDJ44613.1 - 3.4 8.1 7.7 12 6.4 0.1 3.1 2 1 1 3 3 3 0 Transposase DDE domain DHH PF01368.20 CDJ44614.1 - 0.0025 18.0 0.0 0.012 15.8 0.0 2.2 2 2 0 2 2 2 1 DHH family SUIM_assoc PF16619.5 CDJ44614.1 - 0.011 15.8 3.6 0.011 15.8 3.6 2.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ44614.1 - 4.4 7.6 35.8 0.075 13.3 13.1 3.1 2 1 1 3 3 3 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ44614.1 - 6.1 6.7 18.5 11 5.8 18.5 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ44615.1 - 0.14 12.3 5.1 0.2 11.8 5.1 1.2 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 CDJ44615.1 - 0.18 11.8 36.4 0.24 11.3 36.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ44615.1 - 1.8 6.8 24.9 2.2 6.4 24.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 CDJ44615.1 - 2.6 6.9 14.2 3.4 6.5 14.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GREB1 PF15782.5 CDJ44615.1 - 3.1 4.8 13.2 3.8 4.5 13.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mem_trans PF03547.18 CDJ44615.1 - 3.3 6.0 3.7 4.7 5.5 3.7 1.1 1 0 0 1 1 1 0 Membrane transport protein PTPlike_phytase PF14566.6 CDJ44615.1 - 7.4 6.7 9.8 11 6.1 9.8 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Presenilin PF01080.17 CDJ44615.1 - 7.9 5.1 12.0 10 4.7 12.0 1.1 1 0 0 1 1 1 0 Presenilin MutS_IV PF05190.18 CDJ44616.1 - 1.6e-05 25.1 0.1 2.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 MutS family domain IV Exonuc_VII_S PF02609.16 CDJ44616.1 - 0.0029 17.6 0.9 1.6 8.9 0.0 2.9 3 0 0 3 3 3 2 Exonuclease VII small subunit MutS_III PF05192.18 CDJ44616.1 - 0.0039 17.4 0.1 0.0047 17.2 0.1 1.1 1 0 0 1 1 1 1 MutS domain III WD40 PF00400.32 CDJ44617.1 - 5.6e-08 33.3 4.6 0.77 10.7 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat RD3 PF14473.6 CDJ44620.1 - 0.084 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 RD3 protein DUF4800 PF16057.5 CDJ44624.1 - 0.0033 16.8 1.4 0.0045 16.3 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) PsbU PF06514.11 CDJ44624.1 - 0.0087 16.0 0.0 0.054 13.5 0.0 2.1 2 0 0 2 2 2 1 Photosystem II 12 kDa extrinsic protein (PsbU) PIN PF01850.21 CDJ44624.1 - 0.027 15.0 0.7 0.087 13.3 0.1 1.9 2 0 0 2 2 2 0 PIN domain Pkinase PF00069.25 CDJ44625.1 - 7.3e-16 58.3 0.1 4.4e-09 36.1 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ44625.1 - 0.00032 20.1 0.0 0.0013 18.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Mitofilin PF09731.9 CDJ44625.1 - 0.0004 19.4 0.7 0.0004 19.4 0.7 1.4 2 0 0 2 2 2 1 Mitochondrial inner membrane protein HNOBA PF07701.14 CDJ44625.1 - 0.015 14.7 0.9 0.024 14.1 0.9 1.2 1 0 0 1 1 1 0 Heme NO binding associated DUF1633 PF07794.11 CDJ44625.1 - 0.21 9.7 3.0 0.39 8.8 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Suf PF05843.14 CDJ44625.1 - 0.61 10.0 5.3 0.87 9.5 5.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ribosomal_60s PF00428.19 CDJ44625.1 - 9 7.0 21.6 3 8.5 17.2 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein AAA_lid_3 PF17862.1 CDJ44626.1 - 2.2e-11 43.4 0.9 4.7e-11 42.3 0.9 1.7 1 1 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CDJ44626.1 - 3.7e-06 27.4 0.0 1.1e-05 25.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SUIM_assoc PF16619.5 CDJ44626.1 - 0.047 13.8 16.0 0.31 11.1 5.0 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 AF-4 PF05110.13 CDJ44628.1 - 0.28 9.2 6.4 0.31 9.1 6.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein STG PF15809.5 CDJ44628.1 - 0.3 11.1 4.9 0.4 10.7 4.9 1.2 1 0 0 1 1 1 0 Simian taste bud-specific gene product family DUF755 PF05501.11 CDJ44628.1 - 3.7 7.9 11.3 5.6 7.3 11.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RAP1 PF07218.11 CDJ44628.1 - 5.2 5.2 6.6 5.4 5.2 6.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Gar1 PF04410.14 CDJ44629.1 - 5e-18 65.3 0.0 2.5e-17 63.1 0.0 2.1 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region AF-4 PF05110.13 CDJ44631.1 - 0.0014 16.9 10.8 0.0014 16.9 10.8 3.1 3 0 0 3 3 3 1 AF-4 proto-oncoprotein Connexin PF00029.19 CDJ44631.1 - 0.015 15.0 2.5 0.015 15.0 2.5 2.2 2 0 0 2 2 2 0 Connexin Suf PF05843.14 CDJ44631.1 - 0.044 13.8 20.5 0.47 10.4 7.1 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 CDJ44631.1 - 0.12 11.3 18.8 0.22 10.4 5.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ44631.1 - 0.25 11.4 14.6 1.2 9.2 3.6 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MecA PF05389.12 CDJ44631.1 - 0.49 10.0 10.4 1.3 8.6 1.9 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) CDC45 PF02724.14 CDJ44631.1 - 0.56 8.4 13.9 0.037 12.3 2.4 2.1 2 0 0 2 2 2 0 CDC45-like protein SpoIIP PF07454.11 CDJ44631.1 - 1.6 8.1 20.6 0.39 10.1 6.1 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 CDJ44631.1 - 1.7 7.6 16.3 0.17 10.9 4.2 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Presenilin PF01080.17 CDJ44631.1 - 2.1 7.0 28.5 0.52 9.0 10.3 2.3 2 0 0 2 2 2 0 Presenilin DUF2464 PF10240.9 CDJ44631.1 - 2.4 7.7 14.9 0.43 10.1 6.8 2.5 2 0 0 2 2 2 0 Multivesicular body subunit 12 Spt20 PF12090.8 CDJ44631.1 - 2.9 7.5 53.2 5.1 6.6 15.9 2.4 2 0 0 2 2 2 0 Spt20 family Afi1 PF07792.12 CDJ44631.1 - 3.4 8.1 20.3 3.1 8.3 10.4 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SID-1_RNA_chan PF13965.6 CDJ44631.1 - 4.1 5.7 6.2 1.3 7.3 1.3 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.10 CDJ44631.1 - 4.4 7.3 16.7 1.1 9.3 2.3 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3405 PF11885.8 CDJ44631.1 - 4.5 5.8 11.5 3.3 6.2 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3405) Spc24 PF08286.11 CDJ44631.1 - 4.8 7.5 15.8 0.063 13.5 3.8 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1387 PF07139.11 CDJ44631.1 - 4.8 6.8 26.3 0.7 9.6 10.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) DUF913 PF06025.12 CDJ44631.1 - 5 6.0 17.2 1.3 8.0 5.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Mem_trans PF03547.18 CDJ44631.1 - 5.6 5.3 6.9 0.1 10.9 0.1 1.6 2 0 0 2 2 1 0 Membrane transport protein CPSF100_C PF13299.6 CDJ44631.1 - 5.8 7.1 30.8 0.85 9.8 6.3 3.5 4 0 0 4 4 3 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_S64 PF08192.11 CDJ44631.1 - 5.8 5.3 18.4 0.27 9.7 6.5 2.2 2 0 0 2 2 2 0 Peptidase family S64 SURF6 PF04935.12 CDJ44631.1 - 6.7 6.5 31.0 0.085 12.6 9.4 2.8 3 0 0 3 3 3 0 Surfeit locus protein 6 Zip PF02535.22 CDJ44631.1 - 6.9 5.8 11.6 0.35 10.0 0.6 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter SAPS PF04499.15 CDJ44631.1 - 8.5 5.0 15.3 1.2 7.9 4.6 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein TERB2 PF15101.6 CDJ44631.1 - 9.3 6.2 30.9 0.37 10.8 10.4 2.9 3 0 0 3 3 3 0 Telomere-associated protein TERB2 DUF2722 PF10846.8 CDJ44632.1 - 6e-05 22.2 2.1 6e-05 22.2 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) MecA PF05389.12 CDJ44632.1 - 0.0044 16.7 1.6 0.0048 16.5 1.6 1.2 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) Ferlin_C PF16165.5 CDJ44632.1 - 0.013 15.4 4.3 0.021 14.8 4.3 1.3 1 0 0 1 1 1 0 Ferlin C-terminus CPSF100_C PF13299.6 CDJ44632.1 - 0.022 15.0 2.1 0.028 14.6 2.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Afaf PF15339.6 CDJ44632.1 - 0.022 14.5 0.9 0.033 13.9 0.9 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor TMEM51 PF15345.6 CDJ44632.1 - 0.031 14.1 1.1 0.034 14.0 1.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DDHD PF02862.17 CDJ44632.1 - 0.045 13.9 0.5 0.047 13.8 0.5 1.1 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 CDJ44632.1 - 0.049 12.4 0.3 0.042 12.6 0.3 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 CDJ44632.1 - 0.068 12.9 2.0 0.094 12.5 2.0 1.2 1 0 0 1 1 1 0 Connexin EIIBC-GUT_N PF03612.14 CDJ44632.1 - 0.089 12.5 3.8 0.13 12.0 3.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Roughex PF06020.11 CDJ44632.1 - 0.12 11.4 4.4 0.14 11.2 4.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 CDJ44632.1 - 0.13 11.8 12.3 0.17 11.5 12.3 1.1 1 0 0 1 1 1 0 Spt20 family RNA_pol_Rbc25 PF08292.12 CDJ44632.1 - 0.26 11.5 6.1 0.43 10.8 6.1 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 FAM176 PF14851.6 CDJ44632.1 - 0.34 10.6 3.4 0.52 10.0 3.4 1.2 1 0 0 1 1 1 0 FAM176 family DUF3464 PF11947.8 CDJ44632.1 - 1.2 8.9 5.3 1.8 8.3 5.3 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF1682 PF07946.14 CDJ44632.1 - 8.2 5.5 11.7 10 5.2 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RskA PF10099.9 CDJ44633.1 - 0.095 13.0 9.7 0.12 12.6 9.7 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4551 PF15087.6 CDJ44633.1 - 0.24 10.2 10.1 0.27 10.0 10.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Chorion_2 PF03964.15 CDJ44633.1 - 0.29 12.0 8.4 0.37 11.7 8.4 1.2 1 0 0 1 1 1 0 Chorion family 2 Spore_coat_CotO PF14153.6 CDJ44633.1 - 0.46 10.4 14.9 0.55 10.1 14.9 1.0 1 0 0 1 1 1 0 Spore coat protein CotO IHABP4_N PF16174.5 CDJ44633.1 - 0.74 10.4 14.1 0.92 10.1 14.1 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Pex14_N PF04695.13 CDJ44633.1 - 1 10.0 16.4 1.5 9.5 16.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 CDJ44633.1 - 1 9.1 7.8 1.1 9.0 7.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 CDJ44633.1 - 1 9.3 13.9 1.2 9.1 13.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ44633.1 - 1.5 8.7 24.6 1.7 8.6 24.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Stm1_N PF09598.10 CDJ44633.1 - 2.1 9.2 11.4 3.5 8.5 11.4 1.5 1 0 0 1 1 1 0 Stm1 Peroxin-3 PF04882.12 CDJ44633.1 - 3.5 6.5 13.4 4.1 6.3 13.4 1.0 1 0 0 1 1 1 0 Peroxin-3 Presenilin PF01080.17 CDJ44633.1 - 4.8 5.9 11.5 5.3 5.7 11.5 1.0 1 0 0 1 1 1 0 Presenilin Ctr PF04145.15 CDJ44633.1 - 5.2 7.7 5.7 6.7 7.3 5.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Hid1 PF12722.7 CDJ44633.1 - 6.9 4.7 9.4 7.8 4.5 9.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCDC53 PF10152.9 CDJ44633.1 - 7.5 7.0 13.9 11 6.4 13.9 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Peptidase_M16_M PF16187.5 CDJ44634.1 - 3.2e-16 59.5 0.1 1.4e-15 57.4 0.0 1.8 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Spore_III_AF PF09581.10 CDJ44634.1 - 0.51 10.3 1.8 0.78 9.7 1.8 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF2939 PF11159.8 CDJ44634.1 - 3.5 8.1 7.4 49 4.4 8.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) TFIIA PF03153.13 CDJ44634.1 - 4.6 7.1 12.6 6.5 6.6 7.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NPR3 PF03666.13 CDJ44636.1 - 0.0011 17.9 9.8 0.0017 17.2 9.8 1.3 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 V_ATPase_I PF01496.19 CDJ44636.1 - 0.011 13.7 19.3 0.02 12.8 19.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family N6_N4_Mtase PF01555.18 CDJ44636.1 - 0.027 14.2 0.0 0.19 11.4 0.1 1.9 1 1 0 1 1 1 0 DNA methylase Tho2 PF11262.8 CDJ44636.1 - 0.12 11.6 8.1 0.16 11.2 8.1 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CRT10 PF08728.10 CDJ44636.1 - 0.13 10.4 3.4 0.14 10.3 3.4 1.1 1 0 0 1 1 1 0 CRT10 DUF3807 PF12720.7 CDJ44636.1 - 0.23 11.7 26.6 0.42 10.9 23.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) PBP1_TM PF14812.6 CDJ44636.1 - 0.55 10.6 12.7 0.12 12.8 8.3 2.1 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PPL5 PF18168.1 CDJ44636.1 - 0.55 9.5 16.8 0.24 10.7 14.1 1.7 2 0 0 2 2 2 0 Prim-pol family 5 RR_TM4-6 PF06459.12 CDJ44636.1 - 0.62 9.8 22.8 0.82 9.5 19.7 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ44636.1 - 0.67 8.7 12.8 0.16 10.8 9.4 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF3464 PF11947.8 CDJ44636.1 - 0.9 9.3 23.9 0.77 9.5 17.5 3.2 1 1 0 2 2 2 0 Photosynthesis affected mutant 68 HCO3_cotransp PF00955.21 CDJ44636.1 - 1.1 8.0 3.0 1.5 7.5 3.0 1.2 1 0 0 1 1 1 0 HCO3- transporter family Membralin PF09746.9 CDJ44636.1 - 1.1 8.2 7.9 1.8 7.5 7.9 1.3 1 0 0 1 1 1 0 Tumour-associated protein MAJIN PF15077.6 CDJ44636.1 - 1.4 8.7 12.5 2.9 7.6 12.5 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Presenilin PF01080.17 CDJ44636.1 - 1.9 7.2 27.5 0.65 8.7 22.7 1.9 2 0 0 2 2 2 0 Presenilin Zip PF02535.22 CDJ44636.1 - 2.4 7.3 15.3 2.2 7.4 14.7 1.2 1 1 0 1 1 1 0 ZIP Zinc transporter MDM10 PF12519.8 CDJ44636.1 - 2.8 6.7 14.5 0.3 9.9 10.5 1.4 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 DDRGK PF09756.9 CDJ44636.1 - 2.9 7.5 31.1 5.5 6.5 31.1 1.4 1 0 0 1 1 1 0 DDRGK domain DUF2052 PF09747.9 CDJ44636.1 - 2.9 8.0 21.6 3.5 7.7 18.9 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SID-1_RNA_chan PF13965.6 CDJ44636.1 - 4.2 5.7 6.4 5.9 5.2 6.4 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 GAGA_bind PF06217.12 CDJ44636.1 - 5.4 7.2 18.6 1.7 8.9 15.0 1.7 2 0 0 2 2 2 0 GAGA binding protein-like family OATP PF03137.20 CDJ44636.1 - 5.7 5.1 15.2 45 2.1 15.2 1.9 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Tim54 PF11711.8 CDJ44636.1 - 7.9 5.1 17.3 1.3 7.7 13.1 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CSG2 PF16965.5 CDJ44636.1 - 8.1 5.3 8.5 5.7 5.8 6.7 1.6 2 0 0 2 2 2 0 Ceramide synthase regulator BAT2_N PF07001.11 CDJ44636.1 - 9 6.7 29.8 1.5 9.2 2.5 2.3 2 0 0 2 2 2 0 BAT2 N-terminus SAGA-Tad1 PF12767.7 CDJ44636.1 - 9.2 5.9 21.1 5.8 6.6 18.8 1.8 1 1 1 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Tfb4 PF03850.14 CDJ44637.1 - 3.6e-33 115.2 4.3 6.4e-32 111.1 4.3 2.0 1 1 0 1 1 1 1 Transcription factor Tfb4 Kelch_4 PF13418.6 CDJ44638.1 - 9.5e-15 54.4 3.5 5.9e-07 29.4 0.0 4.5 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ44638.1 - 1.3e-09 37.9 0.1 0.0001 22.2 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 CDJ44638.1 - 2.2e-09 37.4 1.0 0.00043 20.5 0.0 3.4 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CDJ44638.1 - 3.8e-06 26.4 11.6 0.014 15.0 0.1 4.8 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CDJ44638.1 - 7.2e-06 26.1 7.7 0.17 12.2 0.0 4.2 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CDJ44638.1 - 0.00016 21.5 12.0 0.014 15.3 0.1 4.2 4 1 0 4 4 4 2 Kelch motif Fcf1 PF04900.12 CDJ44639.1 - 1.9e-10 41.0 0.1 1.9e-05 25.0 0.1 2.7 2 0 0 2 2 2 2 Fcf1 PIN_9 PF18477.1 CDJ44639.1 - 0.1 12.9 1.7 1.8 8.9 0.0 3.1 2 1 1 3 3 3 0 PIN like domain Apt1 PF10351.9 CDJ44639.1 - 0.52 9.1 10.2 0.73 8.6 10.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ44639.1 - 1 9.2 16.8 1.4 8.7 16.8 1.3 1 0 0 1 1 1 0 SPX domain DUF4813 PF16072.5 CDJ44640.1 - 0.6 9.7 28.9 0.72 9.5 28.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF1180 PF06679.12 CDJ44640.1 - 1.1 9.7 6.1 1.2 9.5 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF3275 PF11679.8 CDJ44640.1 - 4.5 7.2 9.3 5.9 6.8 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) EF-hand_6 PF13405.6 CDJ44642.1 - 2.9e-07 29.9 0.1 3e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CDJ44642.1 - 4.1e-07 29.1 0.6 7.9e-06 25.1 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 CDJ44642.1 - 1.7e-06 27.3 0.4 1.2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CDJ44642.1 - 3.7e-05 23.5 0.2 7.5e-05 22.5 0.2 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 CDJ44642.1 - 0.0021 18.4 0.2 0.0095 16.4 0.0 1.8 1 1 0 2 2 2 1 EF-hand domain pair Chloroplast_duf PF14476.6 CDJ44642.1 - 0.0099 14.9 1.1 0.012 14.6 1.1 1.1 1 0 0 1 1 1 1 Petal formation-expressed TRM13 PF05206.14 CDJ44642.1 - 0.011 15.3 0.1 0.015 14.8 0.1 1.1 1 0 0 1 1 1 0 Methyltransferase TRM13 TFIIA PF03153.13 CDJ44642.1 - 0.012 15.6 6.6 0.012 15.6 6.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SIN1 PF05422.12 CDJ44642.1 - 0.019 15.6 2.8 0.024 15.2 2.8 1.1 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) Spt20 PF12090.8 CDJ44642.1 - 0.093 12.3 11.2 0.11 12.1 11.2 1.1 1 0 0 1 1 1 0 Spt20 family Sporozoite_P67 PF05642.11 CDJ44642.1 - 0.2 9.7 2.8 0.22 9.6 2.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2722 PF10846.8 CDJ44642.1 - 0.23 10.4 10.2 0.29 10.0 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SPARC_Ca_bdg PF10591.9 CDJ44642.1 - 0.6 10.4 0.0 0.6 10.4 0.0 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Roughex PF06020.11 CDJ44642.1 - 0.75 8.8 5.5 0.85 8.6 5.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Leo1 PF04004.13 CDJ44643.1 - 1.2e-06 28.5 0.2 2.9e-06 27.2 0.2 1.7 1 0 0 1 1 1 1 Leo1-like protein DUF4893 PF16233.5 CDJ44643.1 - 0.0076 15.9 0.1 0.0076 15.9 0.1 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4893) DUF5597 PF18120.1 CDJ44643.1 - 0.37 10.9 0.1 0.37 10.9 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5597) Spt20 PF12090.8 CDJ44643.1 - 0.67 9.5 6.5 1.4 8.5 6.5 1.6 1 0 0 1 1 1 0 Spt20 family Nop53 PF07767.11 CDJ44644.1 - 0.16 11.3 9.9 0.17 11.2 9.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PV-1 PF06637.11 CDJ44644.1 - 1.9 7.2 9.7 2.4 6.9 9.7 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DivIC PF04977.15 CDJ44645.1 - 3.4 7.5 7.7 23 4.8 0.0 2.7 2 0 0 2 2 2 0 Septum formation initiator RHD_DNA_bind PF00554.22 CDJ44646.1 - 0.077 12.9 2.0 0.09 12.7 1.2 1.4 1 1 0 1 1 1 0 Rel homology DNA-binding domain SUIM_assoc PF16619.5 CDJ44646.1 - 1.5 8.9 12.0 0.21 11.7 6.7 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CTP_transf_like PF01467.26 CDJ44647.1 - 6.3e-10 39.4 0.0 7.8e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 CDJ44647.1 - 0.04 13.8 0.3 0.049 13.5 0.3 1.2 1 0 0 1 1 1 0 FAD synthetase CTP_transf_1 PF01148.20 CDJ44648.1 - 8.4e-39 133.9 5.5 1.4e-38 133.2 5.5 1.3 1 1 0 1 1 1 1 Cytidylyltransferase family DUF755 PF05501.11 CDJ44649.1 - 0.0082 16.4 10.5 0.0082 16.4 10.5 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF755) Zip PF02535.22 CDJ44649.1 - 0.11 11.7 7.8 0.039 13.2 2.6 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4484 PF14831.6 CDJ44649.1 - 0.17 11.9 17.2 0.012 15.7 7.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) RNA_pol_3_Rpc31 PF11705.8 CDJ44649.1 - 0.19 12.0 15.3 0.27 11.5 15.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Dynamin_N PF00350.23 CDJ44649.1 - 1.9 8.5 7.0 47 4.0 0.0 2.3 2 0 0 2 2 2 0 Dynamin family O-antigen_lig PF13425.6 CDJ44649.1 - 6.3 5.5 5.1 0.99 8.1 1.5 1.4 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Cellulose_synt PF03552.14 CDJ44649.1 - 8.9 4.7 5.8 12 4.2 5.8 1.2 1 0 0 1 1 1 0 Cellulose synthase DUF572 PF04502.13 CDJ44649.1 - 9.7 5.7 28.0 14 5.2 28.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SID-1_RNA_chan PF13965.6 CDJ44649.1 - 9.9 4.4 10.9 0.13 10.7 2.7 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 PolyA_pol_arg_C PF12626.7 CDJ44650.1 - 0.042 13.9 0.6 0.042 13.9 0.6 2.5 3 0 0 3 3 3 0 Polymerase A arginine-rich C-terminus DUF1168 PF06658.12 CDJ44650.1 - 0.043 13.6 1.3 0.08 12.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Ribosomal_60s PF00428.19 CDJ44650.1 - 0.068 13.8 1.0 0.068 13.8 1.0 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein ABA_WDS PF02496.16 CDJ44650.1 - 0.38 11.3 3.1 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 ABA/WDS induced protein ADH_zinc_N PF00107.26 CDJ44651.1 - 2.9e-17 62.9 0.4 4.9e-17 62.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDJ44651.1 - 0.00019 21.3 0.0 0.0016 18.3 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDJ44651.1 - 0.00082 20.4 0.1 0.0018 19.3 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAP PF00956.18 CDJ44652.1 - 8.3e-10 38.3 5.0 8.6e-08 31.7 0.1 2.7 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) YL1 PF05764.13 CDJ44652.1 - 0.39 10.8 7.0 0.37 10.9 7.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein PBP1_TM PF14812.6 CDJ44652.1 - 0.48 10.8 7.6 0.65 10.4 6.8 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 CDJ44652.1 - 1.5 8.0 6.5 1.5 8.0 6.5 1.1 1 0 0 1 1 1 0 NOA36 protein Pes-10 PF07149.11 CDJ44652.1 - 1.9 7.5 4.8 1.8 7.5 4.8 1.1 1 0 0 1 1 1 0 Pes-10 Astro_capsid_p PF12226.8 CDJ44652.1 - 2.2 7.4 5.5 2 7.5 5.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-B_dimeris PF09026.10 CDJ44652.1 - 2.9 8.4 12.6 3.9 7.9 12.6 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RCC1_2 PF13540.6 CDJ44653.1 - 2.1e-06 27.4 0.8 0.099 12.5 0.1 3.6 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Med15 PF09606.10 CDJ44653.1 - 0.0059 15.4 27.5 0.015 14.1 6.7 2.1 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.9 CDJ44653.1 - 0.0063 16.8 0.7 0.0063 16.8 0.7 2.4 1 1 0 2 2 2 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ44653.1 - 0.017 14.7 9.8 0.017 14.7 9.8 2.6 2 1 0 2 2 1 0 Spt20 family CAF1 PF04857.20 CDJ44653.1 - 0.021 14.0 2.0 0.039 13.1 2.0 1.4 1 1 0 1 1 1 0 CAF1 family ribonuclease Hydin_ADK PF17213.3 CDJ44653.1 - 0.033 14.5 5.1 1.1 9.5 2.4 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Es2 PF09751.9 CDJ44653.1 - 0.098 12.4 0.2 0.098 12.4 0.2 2.0 2 0 0 2 2 2 0 Nuclear protein Es2 DUF2487 PF10673.9 CDJ44653.1 - 0.12 12.4 8.1 2.6 8.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2487) Cons_hypoth698 PF03601.14 CDJ44653.1 - 0.13 11.1 0.8 0.28 10.0 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 698 ATG2_CAD PF13329.6 CDJ44653.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.4 2 1 0 2 2 2 0 Autophagy-related protein 2 CAD motif DUF4569 PF15133.6 CDJ44653.1 - 0.18 11.5 12.6 0.33 10.6 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) EPL1 PF10513.9 CDJ44653.1 - 0.3 11.5 8.3 3.2 8.1 2.8 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Rsc14 PF08586.10 CDJ44653.1 - 0.8 10.5 0.1 0.8 10.5 0.1 2.8 2 1 1 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit AAL_decarboxy PF03306.13 CDJ44653.1 - 0.92 8.8 7.5 0.11 11.8 0.6 2.1 2 0 0 2 2 2 0 Alpha-acetolactate decarboxylase Fer4_22 PF17179.4 CDJ44653.1 - 5.1 8.0 10.0 3.7 8.5 5.7 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Mcm10 PF09332.11 CDJ44653.1 - 7.5 5.9 16.2 0.4 10.1 3.5 2.0 2 0 0 2 2 2 0 Mcm10 replication factor DUF3552 PF12072.8 CDJ44654.1 - 2.2 7.6 36.4 3.8 6.9 36.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) ADIP PF11559.8 CDJ44654.1 - 5.5 7.1 38.9 7.4 6.6 38.9 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TFIIA PF03153.13 CDJ44655.1 - 0.025 14.6 32.7 0.029 14.4 32.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ44655.1 - 0.049 13.8 9.4 0.058 13.6 9.4 1.2 1 0 0 1 1 1 0 DDHD domain SpoIIP PF07454.11 CDJ44655.1 - 0.055 12.9 9.8 0.063 12.7 9.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CDJ44655.1 - 0.077 12.8 9.7 0.078 12.8 9.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ44655.1 - 0.084 11.6 14.5 0.093 11.5 14.5 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ44655.1 - 0.089 11.8 15.4 0.094 11.7 15.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Connexin PF00029.19 CDJ44655.1 - 0.09 12.5 7.2 0.099 12.4 7.2 1.2 1 0 0 1 1 1 0 Connexin Peptidase_M56 PF05569.11 CDJ44655.1 - 0.14 11.3 0.3 0.17 11.0 0.3 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Band_3_cyto PF07565.13 CDJ44655.1 - 0.28 11.0 10.3 0.32 10.8 10.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CPSF100_C PF13299.6 CDJ44655.1 - 0.41 10.8 16.2 0.4 10.9 15.6 1.3 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Suf PF05843.14 CDJ44655.1 - 0.56 10.1 16.5 0.75 9.7 16.5 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Zip PF02535.22 CDJ44655.1 - 0.58 9.3 6.9 0.66 9.1 6.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TERB2 PF15101.6 CDJ44655.1 - 0.64 10.0 18.3 0.99 9.4 18.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SID-1_RNA_chan PF13965.6 CDJ44655.1 - 0.73 8.2 2.8 0.71 8.2 2.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 V_ATPase_I PF01496.19 CDJ44655.1 - 0.77 7.6 11.0 0.86 7.4 11.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_pol_Rpc4 PF05132.14 CDJ44655.1 - 0.79 10.1 14.6 7 7.1 12.4 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 Neur_chan_memb PF02932.16 CDJ44655.1 - 1.1 9.3 11.3 1.2 9.1 11.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Plasmodium_Vir PF05795.11 CDJ44655.1 - 1.1 8.5 4.9 1.1 8.6 4.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein XAP5 PF04921.14 CDJ44655.1 - 1.7 8.4 15.3 0.67 9.7 11.2 1.9 2 0 0 2 2 2 0 XAP5, circadian clock regulator NARP1 PF12569.8 CDJ44655.1 - 1.9 7.3 13.9 2.1 7.2 13.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EIIBC-GUT_N PF03612.14 CDJ44655.1 - 2.1 8.1 13.7 3 7.5 13.7 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus PAT1 PF09770.9 CDJ44655.1 - 2.2 6.4 25.7 2.1 6.5 25.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 CDJ44655.1 - 2.4 7.7 39.7 3.3 7.3 39.7 1.2 1 0 0 1 1 1 0 Spt20 family Pannexin_like PF12534.8 CDJ44655.1 - 2.5 7.1 8.9 3.3 6.7 8.9 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Pex14_N PF04695.13 CDJ44655.1 - 2.6 8.7 30.1 2.3 8.9 29.3 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Membralin PF09746.9 CDJ44655.1 - 2.8 6.9 7.1 3.3 6.6 7.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein CSG2 PF16965.5 CDJ44655.1 - 2.9 6.8 6.1 3.5 6.5 6.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator EPL1 PF10513.9 CDJ44655.1 - 2.9 8.2 15.6 4.8 7.6 15.6 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like MAJIN PF15077.6 CDJ44655.1 - 3 7.6 14.7 3.8 7.2 14.7 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein FHIPEP PF00771.20 CDJ44655.1 - 3 6.2 8.6 3.6 5.9 8.6 1.1 1 0 0 1 1 1 0 FHIPEP family Eapp_C PF10238.9 CDJ44655.1 - 3 7.9 15.5 0.95 9.5 13.0 1.4 2 0 0 2 2 1 0 E2F-associated phosphoprotein Hid1 PF12722.7 CDJ44655.1 - 3.3 5.7 14.5 3.4 5.7 14.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.6 CDJ44655.1 - 4.1 6.7 15.1 4.8 6.4 15.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CLN3 PF02487.17 CDJ44655.1 - 6.2 5.8 10.6 7.3 5.5 10.6 1.1 1 0 0 1 1 1 0 CLN3 protein Sec62 PF03839.16 CDJ44655.1 - 6.7 6.2 10.6 9.4 5.7 10.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Serinc PF03348.15 CDJ44655.1 - 8.2 5.2 8.7 9.7 5.0 8.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ureide_permease PF07168.11 CDJ44655.1 - 8.2 5.1 7.5 10 4.7 7.5 1.1 1 0 0 1 1 1 0 Ureide permease GREB1 PF15782.5 CDJ44655.1 - 8.6 3.3 16.2 9.5 3.2 16.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BCS1_N PF08740.11 CDJ44657.1 - 3.1e-41 141.4 0.6 7.7e-41 140.1 0.0 1.8 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 CDJ44657.1 - 2e-12 47.7 0.0 5.1e-11 43.1 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 CDJ44657.1 - 0.00098 19.0 3.1 0.06 13.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CDJ44657.1 - 0.0015 18.9 1.3 0.0015 18.9 1.3 3.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 CDJ44657.1 - 0.014 15.6 0.5 0.04 14.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CDJ44657.1 - 0.018 15.0 0.0 0.055 13.4 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 CDJ44657.1 - 0.026 14.1 0.7 0.057 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CDJ44657.1 - 0.06 13.9 0.8 0.35 11.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 CDJ44657.1 - 0.088 13.2 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 CDJ44657.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ44657.1 - 0.11 12.5 0.3 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 CDJ44657.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 KaiC PPV_E1_C PF00519.17 CDJ44657.1 - 0.14 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase Tic110 PF16940.5 CDJ44658.1 - 1.3 7.4 9.7 1.4 7.3 9.7 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter Spt20 PF12090.8 CDJ44659.1 - 0.25 11.0 35.8 0.72 9.4 3.3 3.3 3 0 0 3 3 3 0 Spt20 family FAM199X PF15814.5 CDJ44660.1 - 2.5 7.1 25.1 2.6 7.0 25.1 1.0 1 0 0 1 1 1 0 Protein family FAM199X Pex14_N PF04695.13 CDJ44660.1 - 6.8 7.3 19.1 7.8 7.1 19.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Period_C PF12114.8 CDJ44660.1 - 7.8 6.0 26.1 8 6.0 26.1 1.0 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DAP3 PF10236.9 CDJ44661.1 - 2.6e-06 26.8 0.0 0.00077 18.7 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial ribosomal death-associated protein 3 Sec8_exocyst PF04048.14 CDJ44661.1 - 0.2 11.6 0.0 1.1 9.1 0.0 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain ArsA_ATPase PF02374.15 CDJ44662.1 - 9.5e-39 133.4 0.0 1.1e-38 133.2 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CDJ44662.1 - 9.7e-11 41.9 0.0 1.1e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CDJ44662.1 - 3.1e-10 40.2 0.0 3.1e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CDJ44662.1 - 1.9e-06 27.6 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 CDJ44662.1 - 2.3e-05 24.0 0.1 3.1e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 CDJ44662.1 - 0.0005 19.6 0.0 0.00068 19.2 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 CDJ44662.1 - 0.00056 19.6 0.0 0.00059 19.5 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CDJ44662.1 - 0.0023 17.2 0.0 0.003 16.8 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.22 CDJ44662.1 - 0.0036 16.5 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain APS_kinase PF01583.20 CDJ44662.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase VirC1 PF07015.11 CDJ44662.1 - 0.021 14.1 0.1 0.032 13.5 0.1 1.2 1 0 0 1 1 1 0 VirC1 protein AAA_16 PF13191.6 CDJ44662.1 - 0.024 15.0 0.0 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 CDJ44662.1 - 0.031 14.3 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 CDJ44662.1 - 0.032 13.3 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 CDJ44662.1 - 0.042 13.8 0.9 0.09 12.7 0.7 1.5 1 1 1 2 2 2 0 NACHT domain PTPlike_phytase PF14566.6 CDJ44662.1 - 0.052 13.7 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate IstB_IS21 PF01695.17 CDJ44662.1 - 0.057 13.2 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CDJ44662.1 - 0.057 14.0 0.0 0.069 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 CDJ44662.1 - 0.067 12.5 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ATPase PF06745.13 CDJ44662.1 - 0.077 12.3 0.0 0.094 12.0 0.0 1.1 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 CDJ44662.1 - 0.097 13.2 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 ABC transporter PIF1 PF05970.14 CDJ44662.1 - 0.098 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase MipZ PF09140.11 CDJ44662.1 - 0.13 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ LSDAT_prok PF18171.1 CDJ44662.1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote PhoH PF02562.16 CDJ44662.1 - 0.14 11.6 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein MeaB PF03308.16 CDJ44662.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 CDJ44662.1 - 0.15 11.6 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain Glyco_hydro_9 PF00759.19 CDJ44663.1 - 0.54 9.6 4.8 0.62 9.4 4.8 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Glutaredoxin PF00462.24 CDJ44664.1 - 1.6e-06 28.2 0.1 0.0056 16.9 0.0 2.6 2 0 0 2 2 2 2 Glutaredoxin Caldesmon PF02029.15 CDJ44664.1 - 2.3e-05 23.4 33.1 3.1e-05 22.9 33.1 1.1 1 0 0 1 1 1 1 Caldesmon Presenilin PF01080.17 CDJ44664.1 - 0.00096 18.0 35.5 0.0013 17.5 19.2 2.1 2 0 0 2 2 2 2 Presenilin AbLIM_anchor PF16182.5 CDJ44664.1 - 0.048 13.5 18.5 0.082 12.7 9.8 2.2 2 0 0 2 2 2 0 Putative adherens-junction anchoring region of AbLIM Apt1 PF10351.9 CDJ44664.1 - 0.3 9.9 21.8 0.49 9.2 12.1 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Raftlin PF15250.6 CDJ44664.1 - 0.37 9.5 26.3 0.24 10.1 14.8 2.1 2 0 0 2 2 2 0 Raftlin PNISR PF15996.5 CDJ44664.1 - 0.39 11.0 46.0 0.057 13.7 6.0 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR LMBR1 PF04791.16 CDJ44664.1 - 0.7 8.7 16.3 0.96 8.3 16.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PAT1 PF09770.9 CDJ44664.1 - 1.3 7.2 58.3 0.18 10.0 38.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 CDJ44664.1 - 1.8 8.0 38.1 0.2 11.2 22.5 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist MCM_bind PF09739.9 CDJ44664.1 - 2.7 6.3 30.4 1 7.8 17.4 2.1 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor DUF2052 PF09747.9 CDJ44664.1 - 2.9 8.0 40.7 1.4 9.0 5.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SLC12 PF03522.15 CDJ44664.1 - 5.9 5.8 38.0 3.5 6.6 4.5 2.0 2 0 0 2 2 2 0 Solute carrier family 12 AAA_11 PF13086.6 CDJ44664.1 - 5.9 6.6 33.2 2.3 7.9 3.8 2.3 2 0 0 2 2 2 0 AAA domain Sin_N PF04801.13 CDJ44664.1 - 7.5 5.6 51.6 4.2 6.5 34.9 2.2 2 0 0 2 2 2 0 Sin-like protein conserved region DUF3807 PF12720.7 CDJ44664.1 - 7.6 6.8 53.2 1.2 9.4 7.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) PA26 PF04636.13 CDJ44664.1 - 8.4 5.2 26.5 4.9 6.0 15.9 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Cmc1 PF08583.10 CDJ44665.1 - 7.1e-07 29.2 0.4 7.1e-07 29.2 0.4 2.1 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3138 PF11336.8 CDJ44665.1 - 0.081 11.5 3.1 0.12 11.0 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Dak1 PF02733.17 CDJ44665.1 - 0.2 10.5 0.5 0.3 9.9 0.5 1.2 1 0 0 1 1 1 0 Dak1 domain DUF3464 PF11947.8 CDJ44665.1 - 0.4 10.4 6.5 0.076 12.8 2.7 1.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Suf PF05843.14 CDJ44665.1 - 0.77 9.7 12.5 0.31 11.0 10.0 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ44665.1 - 1 8.0 6.1 1.3 7.7 6.1 1.2 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.22 CDJ44666.1 - 1e-21 76.5 0.0 1.3e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ44666.1 - 0.00033 20.4 0.0 0.00058 19.7 0.0 1.4 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CDJ44666.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 CDJ44666.1 - 0.023 14.3 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V-ATPase_H_N PF03224.14 CDJ44667.1 - 0.0076 15.6 0.1 0.012 14.9 0.0 1.4 1 1 0 1 1 1 1 V-ATPase subunit H Dynamitin PF04912.14 CDJ44668.1 - 0.011 15.1 4.1 0.012 15.0 4.1 1.0 1 0 0 1 1 1 0 Dynamitin V-SNARE_C PF12352.8 CDJ44668.1 - 0.017 15.4 5.1 0.052 13.8 5.1 1.8 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus UPF0242 PF06785.11 CDJ44668.1 - 0.079 13.1 3.7 0.09 12.9 3.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spt20 PF12090.8 CDJ44669.1 - 1.6 8.3 8.3 2.2 7.9 8.3 1.2 1 0 0 1 1 1 0 Spt20 family UPF0560 PF10577.9 CDJ44669.1 - 3.2 6.2 5.9 4.2 5.8 5.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3886 PF13025.6 CDJ44670.1 - 2.8 8.2 17.8 1.3 9.2 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) FTCD_C PF04961.12 CDJ44670.1 - 4.4 7.0 7.0 10 5.9 7.0 1.5 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase Sec20 PF03908.13 CDJ44672.1 - 3.3 7.7 6.6 8.9 6.3 6.6 1.7 1 0 0 1 1 1 0 Sec20 SpoIIE PF07228.12 CDJ44673.1 - 0.00079 19.4 0.0 0.0029 17.5 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Collagen PF01391.18 CDJ44673.1 - 0.074 12.8 20.7 0.16 11.8 20.7 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) SARAF PF06682.12 CDJ44675.1 - 0.44 10.2 7.6 0.46 10.1 7.6 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 CDJ44675.1 - 0.74 10.8 4.5 0.81 10.7 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ44675.1 - 0.85 9.2 15.1 0.98 9.0 15.1 1.1 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ44675.1 - 2.9 6.7 21.5 3.2 6.6 21.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Nha1_C PF08619.10 CDJ44675.1 - 7.8 5.6 15.0 0.39 9.9 7.1 1.9 1 1 1 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus His_Phos_1 PF00300.22 CDJ44676.1 - 2e-38 132.0 0.0 1.8e-30 106.1 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) TAF6_C PF07571.13 CDJ44676.1 - 0.049 14.0 0.0 0.35 11.2 0.0 2.2 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain RAP1 PF07218.11 CDJ44677.1 - 0.36 9.1 17.4 0.86 7.8 1.2 2.1 1 1 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) GYF PF02213.16 CDJ44678.1 - 5.9e-13 48.3 4.0 1.1e-12 47.4 4.0 1.4 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 CDJ44678.1 - 0.00013 21.6 0.5 0.00032 20.4 0.5 1.7 1 0 0 1 1 1 1 GYF domain 2 ICA69 PF04629.14 CDJ44678.1 - 0.023 15.0 4.0 1.7 8.9 1.0 2.1 2 0 0 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain Activator_LAG-3 PF11498.8 CDJ44678.1 - 0.25 10.3 23.5 0.32 9.9 23.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF2722 PF10846.8 CDJ44678.1 - 2.4 7.0 13.5 3 6.7 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ44678.1 - 3.4 8.7 5.3 5 8.1 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ44678.1 - 3.7 7.1 18.3 4.8 6.7 18.3 1.1 1 0 0 1 1 1 0 Spt20 family M_domain PF12938.7 CDJ44678.1 - 4.2 7.1 23.3 6.5 6.5 23.3 1.2 1 0 0 1 1 1 0 M domain of GW182 TFIIA PF03153.13 CDJ44678.1 - 7 6.5 16.8 9.3 6.1 16.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop PF01798.18 CDJ44679.1 - 3.9e-40 137.7 0.2 4.6e-40 137.5 0.2 1.0 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Pro_isomerase PF00160.21 CDJ44681.1 - 7.9e-42 143.2 0.1 1.3e-41 142.5 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.28 CDJ44681.1 - 1.5e-33 115.0 0.0 4.8e-33 113.3 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 CDJ44681.1 - 6.6e-11 41.5 11.8 0.0016 18.4 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ44681.1 - 1.9e-10 41.2 8.9 5.4e-08 33.4 2.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ44681.1 - 1e-08 34.7 9.3 0.044 13.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ44681.1 - 1.4e-07 31.1 8.7 0.0011 18.6 0.1 3.4 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 CDJ44681.1 - 2.2e-07 30.5 6.6 0.037 14.2 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ44681.1 - 1.2e-06 28.9 3.6 0.00099 19.6 0.9 2.8 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ44681.1 - 7.7e-06 26.3 5.2 0.044 14.6 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ44681.1 - 4.4e-05 23.6 0.4 0.15 12.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ44681.1 - 0.0028 17.8 0.2 0.0062 16.7 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ44681.1 - 0.021 15.0 0.9 0.054 13.7 0.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDJ44681.1 - 0.21 11.9 8.0 0.19 12.0 1.5 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Memo PF01875.17 CDJ44682.1 - 4.9e-09 35.7 0.0 5.2e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Spt20 PF12090.8 CDJ44683.1 - 0.00033 20.4 2.5 0.00038 20.1 2.5 1.1 1 0 0 1 1 1 1 Spt20 family BAF1_ABF1 PF04684.13 CDJ44683.1 - 1.3 7.9 5.8 1.6 7.7 5.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Hamartin PF04388.12 CDJ44683.1 - 3.6 6.1 7.5 4.1 5.9 7.5 1.0 1 0 0 1 1 1 0 Hamartin protein DSPc PF00782.20 CDJ44684.1 - 1.2e-17 64.0 0.1 1.5e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ44684.1 - 0.15 11.6 0.1 0.19 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SUIM_assoc PF16619.5 CDJ44685.1 - 0.0035 17.4 0.3 0.0035 17.4 0.3 4.4 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 CDJ44685.1 - 0.022 15.3 1.5 0.022 15.3 1.5 5.3 5 0 0 5 5 5 0 60s Acidic ribosomal protein DUF2722 PF10846.8 CDJ44685.1 - 0.12 11.3 10.4 0.43 9.5 1.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) TUSC2 PF15000.6 CDJ44686.1 - 0.2 12.0 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Tumour suppressor candidate 2 DUF456 PF04306.13 CDJ44687.1 - 0.093 13.0 0.0 0.093 13.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF456) DUF883 PF05957.13 CDJ44687.1 - 0.58 10.8 10.7 1 10.0 10.7 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Ribosomal_60s PF00428.19 CDJ44687.1 - 2.7 8.6 9.9 4.3 8.0 9.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ44687.1 - 7.7 6.1 11.0 9.8 5.7 11.0 1.0 1 0 0 1 1 1 0 Spt20 family Virul_fac_BrkB PF03631.15 CDJ44688.1 - 0.036 13.7 0.3 0.036 13.7 0.3 2.3 2 1 1 3 3 3 0 Virulence factor BrkB TFIIA PF03153.13 CDJ44688.1 - 0.081 12.9 47.9 0.1 12.6 47.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 CDJ44688.1 - 0.87 7.6 15.7 1.1 7.3 15.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAPT PF11770.8 CDJ44688.1 - 1.8 8.4 0.0 1.8 8.4 0.0 2.5 3 0 0 3 3 3 0 GRB2-binding adapter (GAPT) Hamartin PF04388.12 CDJ44688.1 - 1.9 7.1 17.0 2.3 6.8 17.0 1.1 1 0 0 1 1 1 0 Hamartin protein DUF4551 PF15087.6 CDJ44688.1 - 3.6 6.3 14.7 4.4 6.0 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3584 PF12128.8 CDJ44688.1 - 9.3 3.6 38.4 14 3.0 38.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) baeRF_family10 PF18854.1 CDJ44689.1 - 0.15 12.3 5.0 7.2 6.8 2.9 2.3 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 DUF2057 PF09829.9 CDJ44689.1 - 4.1 7.5 19.2 0.34 11.1 8.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) SPX PF03105.19 CDJ44690.1 - 1.4 8.7 12.9 42 3.9 0.0 2.0 2 0 0 2 2 2 0 SPX domain SOG2 PF10428.9 CDJ44690.1 - 9.7 5.3 13.7 0.98 8.5 4.6 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein DUF2063 PF09836.9 CDJ44691.1 - 0.00025 21.2 3.3 2.1 8.6 0.5 3.6 1 1 2 3 3 3 2 Putative DNA-binding domain AAA_lid_7 PF17867.1 CDJ44691.1 - 0.063 13.5 3.7 3.6 7.8 0.4 2.6 1 1 1 2 2 2 0 Midasin AAA lid domain Baculo_PEP_C PF04513.12 CDJ44691.1 - 0.27 11.2 5.7 0.34 10.9 5.7 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAD_SOX PF18371.1 CDJ44691.1 - 0.41 11.0 5.6 4.4 7.7 5.5 2.1 1 1 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Nop14 PF04147.12 CDJ44691.1 - 0.92 7.6 3.2 0.97 7.6 3.2 1.0 1 0 0 1 1 1 0 Nop14-like family P22_AR_C PF10548.9 CDJ44691.1 - 1.6 8.9 6.0 32 4.8 5.5 3.1 1 1 0 1 1 1 0 P22AR C-terminal domain HrpJ PF07201.11 CDJ44691.1 - 8.8 6.6 15.7 17 5.7 15.7 1.6 1 1 0 1 1 1 0 HrpJ-like domain Ribosomal_60s PF00428.19 CDJ44692.1 - 0.39 11.3 9.1 0.68 10.6 9.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3446 PF11928.8 CDJ44693.1 - 1.5 9.1 17.6 0.37 11.1 1.1 2.1 1 1 1 2 2 2 0 Early growth response N-terminal domain Metallophos PF00149.28 CDJ44694.1 - 8.3e-20 72.2 0.0 1.3e-19 71.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Chlam_OMP3 PF03503.13 CDJ44694.1 - 0.067 13.5 0.2 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 Peptidase_M1_N PF17900.1 CDJ44695.1 - 6.7e-08 32.9 0.0 8.1e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Bax1-I PF01027.20 CDJ44696.1 - 2.3e-36 125.6 33.9 2.6e-36 125.4 33.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF368 PF04018.13 CDJ44696.1 - 0.89 9.1 23.6 0.017 14.7 11.9 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF368) DUF883 PF05957.13 CDJ44698.1 - 0.004 17.7 5.6 0.004 17.7 5.6 2.1 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) RskA PF10099.9 CDJ44698.1 - 0.0058 17.0 5.6 0.0076 16.6 5.6 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF4670 PF15709.5 CDJ44698.1 - 0.5 9.6 18.1 0.62 9.3 18.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) Arg_decarbox_C PF17944.1 CDJ44698.1 - 2.2 8.9 8.2 4.7 7.8 8.2 1.7 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension UVR PF02151.19 CDJ44700.1 - 0.011 15.5 11.9 0.069 12.9 2.6 3.0 2 0 0 2 2 2 0 UvrB/uvrC motif SR-25 PF10500.9 CDJ44700.1 - 0.41 10.2 7.4 0.066 12.8 3.1 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein WD40 PF00400.32 CDJ44701.1 - 9.2e-27 92.8 0.2 3.3e-08 34.0 0.0 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ44701.1 - 7.1e-08 32.6 0.0 0.00028 21.1 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain TMEM247 PF15444.6 CDJ44702.1 - 0.0092 16.0 1.4 0.0092 16.0 1.4 2.7 3 0 0 3 3 3 1 Transmembrane protein 247 PP2C PF00481.21 CDJ44703.1 - 3.9e-06 26.7 0.0 5.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PepSY PF03413.19 CDJ44703.1 - 0.019 15.5 0.0 0.035 14.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain hGDE_central PF14702.6 CDJ44704.1 - 4e-50 170.9 0.0 7.4e-50 170.0 0.0 1.4 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme AMPK1_CBM PF16561.5 CDJ44704.1 - 7.5e-17 61.3 0.0 6.6e-16 58.3 0.0 2.2 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase Sel1 PF08238.12 CDJ44705.1 - 2.1e-23 82.2 3.3 6.6e-05 23.5 0.0 5.5 5 0 0 5 5 5 4 Sel1 repeat HSP20 PF00011.21 CDJ44706.1 - 5.2e-13 49.0 0.0 4.5e-12 46.0 0.0 2.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ44706.1 - 0.0015 18.1 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Dynamin_N PF00350.23 CDJ44706.1 - 0.041 14.0 0.3 0.14 12.2 0.3 1.8 1 1 0 1 1 1 0 Dynamin family Corona_I PF03187.14 CDJ44706.1 - 0.09 12.4 0.4 7.7 6.1 0.0 2.2 1 1 1 2 2 2 0 Corona nucleocapsid I protein CODH_A_N PF18537.1 CDJ44706.1 - 0.13 12.3 0.0 0.49 10.4 0.0 1.9 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Spt20 PF12090.8 CDJ44706.1 - 0.29 10.7 11.3 0.49 10.0 11.3 1.3 1 0 0 1 1 1 0 Spt20 family eIF3_p135 PF12807.7 CDJ44707.1 - 0.03 14.3 0.0 0.031 14.3 0.0 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 DUF4834 PF16118.5 CDJ44707.1 - 0.33 11.9 2.0 0.36 11.8 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ44707.1 - 1.5 8.4 10.4 1.5 8.4 10.4 1.0 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ44707.1 - 5.5 5.7 14.9 5.9 5.6 14.9 1.1 1 0 0 1 1 1 0 Androgen receptor GDE_C PF06202.14 CDJ44708.1 - 3.7e-09 36.0 0.0 3.8e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase SART-1 PF03343.13 CDJ44709.1 - 1.8e-17 63.2 1.8 2e-17 63.0 1.8 1.1 1 0 0 1 1 1 1 SART-1 family MCCD1 PF15707.5 CDJ44711.1 - 2.1 8.9 4.3 1.6 9.2 2.7 1.8 1 1 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 FSA_C PF10479.9 CDJ44711.1 - 7.4 4.6 6.1 8.4 4.4 6.1 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SUIM_assoc PF16619.5 CDJ44712.1 - 1.9e-05 24.6 0.3 5.4e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ44712.1 - 0.054 13.1 4.1 0.071 12.7 4.1 1.3 1 0 0 1 1 1 0 Spt20 family DUF5345 PF17280.2 CDJ44712.1 - 0.92 9.5 5.7 1.5 8.8 5.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5345) DUF3446 PF11928.8 CDJ44712.1 - 1.4 9.2 30.8 1.5 9.1 16.1 2.7 3 0 0 3 3 3 0 Early growth response N-terminal domain RAP1 PF07218.11 CDJ44712.1 - 7.3 4.7 10.2 10 4.3 10.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Exo_endo_phos PF03372.23 CDJ44713.1 - 6.3e-12 45.5 0.0 3.7e-11 43.0 0.0 2.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Secretin_N_2 PF07655.13 CDJ44713.1 - 0.017 15.7 11.7 0.017 15.7 11.7 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain NAM-associated PF14303.6 CDJ44713.1 - 0.1 13.3 0.3 0.1 13.3 0.3 4.2 5 0 0 5 5 5 0 No apical meristem-associated C-terminal domain Apt1 PF10351.9 CDJ44713.1 - 4.3 6.1 10.3 0.056 12.3 0.8 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain SUIM_assoc PF16619.5 CDJ44713.1 - 7.1 6.8 20.0 0.62 10.2 0.9 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PGK PF00162.19 CDJ44714.1 - 3.2e-33 115.2 0.5 3.5e-33 115.1 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Lipoprotein_2 PF00921.17 CDJ44714.1 - 0.03 13.9 1.1 0.031 13.8 1.1 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein K_channel_TID PF07941.11 CDJ44714.1 - 0.031 14.7 3.0 0.05 14.1 3.0 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Ras PF00071.22 CDJ44715.1 - 9.3e-15 54.6 0.2 9.8e-15 54.5 0.2 1.0 1 0 0 1 1 1 1 Ras family P3A PF08727.11 CDJ44715.1 - 0.016 14.6 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Poliovirus 3A protein like RsgA_GTPase PF03193.16 CDJ44715.1 - 0.1 12.5 0.0 0.1 12.5 0.0 1.0 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 CDJ44716.1 - 7.8e-17 61.9 0.0 1.3e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ44716.1 - 5.9e-07 29.2 0.3 5.9e-07 29.2 0.3 2.3 3 0 0 3 3 3 1 AAA+ lid domain RuvB_N PF05496.12 CDJ44716.1 - 0.0004 20.2 0.0 0.00077 19.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CDJ44716.1 - 0.0033 16.7 0.0 0.0049 16.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 CDJ44716.1 - 0.0034 17.8 0.3 0.039 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 CDJ44716.1 - 0.038 13.4 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CDJ44716.1 - 0.048 13.6 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 CDJ44716.1 - 0.055 13.6 0.3 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDJ44716.1 - 0.06 13.4 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CDJ44716.1 - 0.22 11.9 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Nha1_C PF08619.10 CDJ44717.1 - 0.11 11.7 7.7 0.13 11.5 7.7 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus TFIIA PF03153.13 CDJ44717.1 - 0.36 10.8 37.5 0.41 10.6 37.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPC22 PF04573.12 CDJ44720.1 - 0.16 11.4 0.6 7.1 6.1 0.2 2.6 2 0 0 2 2 2 0 Signal peptidase subunit DUF5319 PF17252.2 CDJ44720.1 - 0.6 10.3 5.5 11 6.3 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5319) Porphobil_deam PF01379.20 CDJ44721.1 - 1.2e-43 149.0 11.4 2.2e-38 131.8 6.7 3.8 2 1 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CDJ44721.1 - 2.1e-13 50.5 0.1 6.8e-13 48.8 0.1 1.9 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain SUIM_assoc PF16619.5 CDJ44721.1 - 0.085 12.9 22.4 1.2 9.2 0.2 3.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ44721.1 - 8.2 6.0 11.8 12 5.4 1.4 3.1 3 0 0 3 3 3 0 Spt20 family Suf PF05843.14 CDJ44722.1 - 0.18 11.8 1.6 0.16 11.9 1.6 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Androgen_recep PF02166.16 CDJ44722.1 - 6.6 5.5 11.5 6.7 5.4 11.5 1.0 1 0 0 1 1 1 0 Androgen receptor DUF2264 PF10022.9 CDJ44723.1 - 0.12 11.5 0.2 0.12 11.4 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) ERM PF00769.19 CDJ44723.1 - 0.2 11.5 21.3 0.25 11.2 21.3 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF724 PF05266.14 CDJ44723.1 - 0.43 10.4 10.5 0.52 10.1 9.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMPIT PF07851.13 CDJ44723.1 - 0.75 9.0 4.1 0.9 8.7 4.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.9 CDJ44723.1 - 1.2 8.1 6.7 1.3 8.0 6.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 3HCDH_N PF02737.18 CDJ44723.1 - 1.5 8.6 7.4 2 8.3 7.4 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CorA PF01544.18 CDJ44724.1 - 1.4 8.2 5.3 2.3 7.5 5.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Peptidase_S49_N PF08496.10 CDJ44725.1 - 0.23 11.5 14.0 0.12 12.5 6.6 2.4 2 1 0 2 2 2 0 Peptidase family S49 N-terminal RskA PF10099.9 CDJ44725.1 - 0.29 11.4 18.5 0.1 12.9 5.5 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ44725.1 - 6.9 6.2 37.6 1.2 8.7 9.7 3.2 3 0 0 3 3 3 0 Spt20 family DUF547 PF04784.14 CDJ44726.1 - 2.5e-10 40.4 0.0 1e-09 38.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF547 TPR_2 PF07719.17 CDJ44727.1 - 2.2e-05 24.2 0.4 7.1e-05 22.6 0.4 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ44727.1 - 0.00026 20.7 0.5 0.00043 20.0 0.5 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ44727.1 - 0.0022 17.7 0.1 0.0063 16.2 0.0 1.8 1 1 0 1 1 1 1 TPR repeat TPR_14 PF13428.6 CDJ44727.1 - 0.0041 17.8 0.0 0.0041 17.8 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 CDJ44727.1 - 0.012 15.7 0.1 0.012 15.7 0.1 1.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 CDJ44727.1 - 0.023 15.3 0.2 0.023 15.3 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PRP38_assoc PF12871.7 CDJ44727.1 - 4.6 7.9 22.7 0.56 10.9 6.6 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Lin-8 PF03353.15 CDJ44727.1 - 5.2 6.5 7.8 9.7 5.7 7.8 1.5 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist FXMRP1_C_core PF12235.8 CDJ44727.1 - 6.6 7.4 17.1 1.6 9.4 4.7 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Siah-Interact_N PF09032.11 CDJ44727.1 - 9.8 6.6 8.7 0.95 9.8 1.9 2.5 2 1 0 2 2 2 0 Siah interacting protein, N terminal DUF755 PF05501.11 CDJ44728.1 - 0.0079 16.5 10.3 0.011 16.0 10.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF755) DUF1180 PF06679.12 CDJ44728.1 - 0.47 10.9 4.5 0.51 10.8 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4692 PF15763.5 CDJ44728.1 - 2 8.9 6.0 2.1 8.8 6.0 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Herpes_DNAp_acc PF04929.12 CDJ44728.1 - 3.9 6.3 6.6 3.9 6.3 6.6 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ras PF00071.22 CDJ44730.1 - 1.9e-52 177.1 0.0 2.3e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ44730.1 - 1.1e-31 109.6 0.0 1.5e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ44730.1 - 7e-10 38.6 0.0 8.8e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ44730.1 - 3e-06 26.9 0.0 6.3e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ44730.1 - 0.00039 20.4 0.1 0.6 10.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDJ44730.1 - 0.00057 20.0 0.0 0.00077 19.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ44730.1 - 0.0021 17.5 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 CDJ44730.1 - 0.0055 17.1 0.7 0.0083 16.5 0.6 1.4 1 1 0 1 1 1 1 AAA ATPase domain Alpha-amylase_C PF02806.18 CDJ44731.1 - 6.3e-07 29.8 0.0 1.7e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Presenilin PF01080.17 CDJ44732.1 - 1.5e-06 27.3 12.5 1.5e-06 27.3 12.5 3.3 2 1 0 2 2 2 1 Presenilin DUF4661 PF15576.6 CDJ44732.1 - 0.00024 21.1 2.6 0.00024 21.1 2.6 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4661) DUF1676 PF07898.13 CDJ44732.1 - 0.064 13.3 8.5 0.023 14.8 2.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) TT_ORF1 PF02956.14 CDJ44732.1 - 0.29 9.8 23.9 0.36 9.4 9.9 3.0 3 0 0 3 3 3 0 TT viral orf 1 Anticodon_1 PF08264.13 CDJ44734.1 - 0.00035 20.5 0.0 0.00042 20.3 0.0 1.1 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Spt20 PF12090.8 CDJ44734.1 - 0.67 9.5 9.1 0.95 9.0 9.1 1.1 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ44734.1 - 2.3 7.2 6.0 3 6.9 6.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein RskA PF10099.9 CDJ44735.1 - 0.00015 22.1 2.6 0.0002 21.7 2.6 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ44735.1 - 0.00024 21.3 3.1 0.00024 21.3 3.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ44735.1 - 0.0025 18.7 0.2 0.0029 18.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ44735.1 - 0.0074 15.9 14.3 0.0089 15.7 14.3 1.1 1 0 0 1 1 1 1 Spt20 family DcuA_DcuB PF03605.14 CDJ44735.1 - 0.041 12.8 0.2 0.054 12.4 0.2 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Cellulose_synt PF03552.14 CDJ44735.1 - 0.12 10.8 2.6 0.15 10.5 2.6 1.1 1 0 0 1 1 1 0 Cellulose synthase DAD PF02109.16 CDJ44735.1 - 0.19 12.0 0.3 0.26 11.6 0.3 1.2 1 0 0 1 1 1 0 DAD family Ureide_permease PF07168.11 CDJ44735.1 - 0.26 10.0 1.7 0.32 9.7 1.7 1.1 1 0 0 1 1 1 0 Ureide permease eIF-3_zeta PF05091.12 CDJ44735.1 - 0.26 10.2 5.4 0.3 10.0 5.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TMEM51 PF15345.6 CDJ44735.1 - 1.7 8.4 7.9 2.7 7.8 7.9 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 DUF2722 PF10846.8 CDJ44735.1 - 5.8 5.7 16.8 7.2 5.4 16.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Histone PF00125.24 CDJ44736.1 - 9.9e-36 123.0 0.7 2.4e-34 118.5 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CDJ44736.1 - 6.2e-05 23.1 0.0 9.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CDJ44736.1 - 0.052 13.9 0.0 0.075 13.4 0.0 1.3 1 0 0 1 1 1 0 CENP-S protein SR-25 PF10500.9 CDJ44736.1 - 0.24 11.0 5.4 0.35 10.4 5.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ44736.1 - 1 9.5 11.0 2 8.5 11.0 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 AF-4 PF05110.13 CDJ44737.1 - 0.22 9.6 7.4 0.25 9.4 7.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ipi1_N PF12333.8 CDJ44737.1 - 0.44 11.2 3.6 1.4 9.6 3.6 2.0 1 1 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation DUF515 PF04415.12 CDJ44737.1 - 4.6 5.5 5.3 5.8 5.2 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Glyco_transf_5 PF08323.11 CDJ44739.1 - 6.1e-31 108.0 0.0 1.5e-30 106.7 0.0 1.6 2 0 0 2 2 2 1 Starch synthase catalytic domain AMPK1_CBM PF16561.5 CDJ44739.1 - 2.1e-17 63.1 0.0 5.4e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Glycos_transf_1 PF00534.20 CDJ44739.1 - 1.1e-12 47.8 0.0 2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ44739.1 - 5.4e-07 30.1 0.0 1.3e-06 28.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Sec3_C PF09763.9 CDJ44739.1 - 2 6.7 3.8 2.8 6.2 3.8 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 Spt20 PF12090.8 CDJ44741.1 - 0.00012 21.7 38.3 0.07 12.7 7.7 3.2 3 0 0 3 3 3 3 Spt20 family LCD1 PF09798.9 CDJ44741.1 - 0.00085 18.0 0.0 0.026 13.0 0.0 2.2 2 1 0 2 2 2 1 DNA damage checkpoint protein Nop25 PF09805.9 CDJ44741.1 - 2.3 8.7 15.3 0.77 10.2 4.6 3.1 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) WD40 PF00400.32 CDJ44742.1 - 2.8e-22 78.6 0.2 4e-11 43.3 0.2 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ44742.1 - 5.3e-10 39.5 0.1 9.5e-05 22.6 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ44742.1 - 0.00026 20.0 0.0 0.021 13.8 0.0 2.1 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDJ44742.1 - 0.0088 15.9 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A TruB_C PF09142.11 CDJ44742.1 - 0.035 13.9 0.9 0.078 12.8 0.2 1.8 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal DEAD PF00270.29 CDJ44743.1 - 2.6e-12 46.9 0.1 2.9e-12 46.7 0.1 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF866 PF05907.13 CDJ44744.1 - 8.6e-35 119.9 0.0 9.7e-35 119.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) cwf18 PF08315.12 CDJ44745.1 - 1.5e-25 90.5 1.0 1.5e-25 90.5 1.0 1.8 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor DUF3987 PF13148.6 CDJ44745.1 - 0.58 9.1 4.5 0.21 10.6 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) PA14 PF07691.12 CDJ44746.1 - 8.5e-07 28.9 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 PA14 domain RRN3 PF05327.11 CDJ44747.1 - 3.7e-22 78.6 0.2 4.2e-22 78.4 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DUF1539 PF07560.11 CDJ44747.1 - 0.038 14.1 0.1 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) NAD_binding_4 PF07993.12 CDJ44747.1 - 0.055 12.6 0.1 0.083 12.0 0.1 1.2 1 0 0 1 1 1 0 Male sterility protein Ribosomal_60s PF00428.19 CDJ44747.1 - 0.79 10.3 20.0 0.076 13.6 5.3 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribul_P_3_epim PF00834.19 CDJ44748.1 - 8.8e-08 31.8 0.0 9.5e-08 31.7 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Ribosomal_60s PF00428.19 CDJ44749.1 - 3.9 8.1 12.4 7.5 7.2 12.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Chorismate_bind PF00425.18 CDJ44750.1 - 0.024 14.2 0.6 0.028 14.0 0.6 1.3 1 0 0 1 1 1 0 chorismate binding enzyme DUF1759 PF03564.15 CDJ44750.1 - 0.063 13.2 0.9 0.09 12.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF3461 PF11944.8 CDJ44750.1 - 0.09 12.9 1.1 0.16 12.1 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) Ead_Ea22 PF13935.6 CDJ44750.1 - 0.13 12.9 6.8 0.53 11.0 6.8 2.0 1 1 0 1 1 1 0 Ead/Ea22-like protein Pheromone PF08015.11 CDJ44750.1 - 0.15 13.1 12.1 1.2 10.2 12.1 2.3 1 1 0 1 1 1 0 Fungal mating-type pheromone Activator_LAG-3 PF11498.8 CDJ44750.1 - 0.28 10.1 23.1 0.32 9.9 23.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 V_ATPase_I PF01496.19 CDJ44750.1 - 3.6 5.4 6.7 4.2 5.2 6.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ44751.1 - 6.4 6.6 22.6 8.1 6.3 22.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1635 PF07795.11 CDJ44752.1 - 0.00045 20.2 1.3 0.00069 19.6 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) SPX PF03105.19 CDJ44752.1 - 0.076 12.9 2.1 0.089 12.7 2.1 1.1 1 0 0 1 1 1 0 SPX domain PAP1 PF08601.10 CDJ44752.1 - 0.19 11.4 7.0 0.26 10.9 7.0 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 DUF515 PF04415.12 CDJ44752.1 - 0.25 9.7 7.6 0.29 9.5 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) NAM-associated PF14303.6 CDJ44752.1 - 0.62 10.8 3.3 0.99 10.1 3.3 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CCDC106 PF15794.5 CDJ44752.1 - 1.1 9.0 6.8 1.5 8.5 6.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 MGC-24 PF05283.11 CDJ44752.1 - 1.3 9.5 6.9 2.2 8.7 6.9 1.4 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Miga PF10265.9 CDJ44752.1 - 1.5 7.8 5.3 1.8 7.4 5.3 1.1 1 0 0 1 1 1 0 Mitoguardin DUF1180 PF06679.12 CDJ44752.1 - 2.1 8.7 11.7 0.19 12.1 6.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) AF-4 PF05110.13 CDJ44752.1 - 5.8 4.9 18.4 7.2 4.6 18.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Tmemb_14 PF03647.13 CDJ44754.1 - 2.1 9.1 11.8 1.6 9.5 4.7 2.5 2 1 0 2 2 2 0 Transmembrane proteins 14C Sugar_tr PF00083.24 CDJ44755.1 - 5.5e-20 71.7 12.3 6.5e-20 71.4 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ44755.1 - 2.6e-13 49.6 19.0 3e-13 49.4 19.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CDJ44755.1 - 0.14 11.0 5.4 0.59 8.9 5.5 1.8 1 1 0 1 1 1 0 MFS_1 like family Peptidase_S64 PF08192.11 CDJ44757.1 - 0.91 7.9 16.5 1.1 7.7 16.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ribosomal_60s PF00428.19 CDJ44757.1 - 1.9 9.1 13.4 3.1 8.5 13.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Vfa1 PF08432.10 CDJ44757.1 - 2.8 8.2 13.1 0.39 11.0 9.2 1.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Tmemb_cc2 PF10267.9 CDJ44757.1 - 6.1 5.9 12.8 8.5 5.4 12.8 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein AF-4 PF05110.13 CDJ44757.1 - 6.3 4.8 37.5 7.7 4.5 37.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein LIAS_N PF16881.5 CDJ44758.1 - 0.071 13.5 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family TFIIA PF03153.13 CDJ44758.1 - 0.64 10.0 5.8 0.77 9.7 5.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 CDJ44759.1 - 0.012 14.5 8.2 0.013 14.3 8.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 CDJ44759.1 - 0.41 8.9 9.3 0.44 8.8 9.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ASFV_J13L PF05568.11 CDJ44759.1 - 0.53 10.0 5.0 1.6 8.5 4.9 2.0 1 1 0 1 1 1 0 African swine fever virus J13L protein Ndc1_Nup PF09531.10 CDJ44759.1 - 1 8.0 8.9 1.2 7.7 8.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 CDJ44759.1 - 1.2 7.6 9.8 1.6 7.2 9.8 1.1 1 0 0 1 1 1 0 Macoilin family NAM-associated PF14303.6 CDJ44759.1 - 5.2 7.8 10.0 7.3 7.3 10.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RrnaAD PF00398.20 CDJ44761.1 - 4.5e-19 68.5 0.0 1.2e-18 67.1 0.0 1.6 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 CDJ44761.1 - 0.00037 20.4 0.0 0.0011 18.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ44761.1 - 0.016 15.9 0.0 0.046 14.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain NodS PF05401.11 CDJ44761.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) SUIM_assoc PF16619.5 CDJ44761.1 - 0.11 12.5 9.8 0.099 12.7 1.8 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Methyltransf_11 PF08241.12 CDJ44761.1 - 0.12 13.1 0.0 0.33 11.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Rhomboid PF01694.22 CDJ44762.1 - 1.9e-27 96.1 14.3 2.8e-27 95.6 14.3 1.2 1 0 0 1 1 1 1 Rhomboid family SIP1 PF04938.12 CDJ44762.1 - 0.04 13.6 0.4 0.064 13.0 0.4 1.2 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) RIB43A PF05914.12 CDJ44765.1 - 0.004 15.9 3.3 0.0044 15.8 3.3 1.1 1 0 0 1 1 1 1 RIB43A DUF4232 PF14016.6 CDJ44765.1 - 0.0042 17.2 1.4 0.0048 17.0 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4232) Spt20 PF12090.8 CDJ44765.1 - 0.021 14.4 3.9 0.022 14.4 3.9 1.1 1 0 0 1 1 1 0 Spt20 family tRNA-synt_1 PF00133.22 CDJ44765.1 - 0.17 10.1 0.0 0.18 10.0 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) SUIM_assoc PF16619.5 CDJ44765.1 - 0.62 10.2 12.3 1 9.5 12.3 1.5 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ44766.1 - 0.0059 16.3 4.6 0.0065 16.1 4.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 CDJ44766.1 - 0.013 14.0 0.5 0.013 13.9 0.5 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Pheromone PF08015.11 CDJ44766.1 - 0.048 14.7 1.2 0.066 14.3 1.2 1.2 1 0 0 1 1 1 0 Fungal mating-type pheromone DUF755 PF05501.11 CDJ44766.1 - 0.77 10.0 11.0 1.2 9.4 11.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ44769.1 - 7.7e-07 29.0 8.8 1.1e-06 28.4 8.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TAF1D PF15333.6 CDJ44769.1 - 0.12 12.1 4.5 0.2 11.3 4.5 1.4 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D VIT1 PF01988.19 CDJ44769.1 - 0.21 11.4 3.7 0.14 12.0 1.4 1.8 2 0 0 2 2 2 0 VIT family DUF3446 PF11928.8 CDJ44769.1 - 2.1 8.7 15.0 9.7 6.6 12.4 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain Peptidase_S64 PF08192.11 CDJ44769.1 - 3.6 6.0 15.3 4.6 5.6 15.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4692 PF15763.5 CDJ44769.1 - 6.8 7.1 15.6 0.33 11.4 8.4 2.0 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) CCDC14 PF15254.6 CDJ44770.1 - 0.098 11.3 0.3 0.12 11.0 0.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 SRPRB PF09439.10 CDJ44771.1 - 3.2e-16 59.3 0.0 4e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CDJ44771.1 - 1.1e-06 28.2 0.0 1.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ44771.1 - 4.9e-05 23.0 0.0 6.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CDJ44771.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.3 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 CDJ44771.1 - 0.034 14.2 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3138 PF11336.8 CDJ44771.1 - 4.4 5.8 4.7 5.8 5.4 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_60s PF00428.19 CDJ44771.1 - 7.4 7.2 20.0 0.54 10.9 12.5 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF4614 PF15391.6 CDJ44772.1 - 7.6 6.5 19.1 10 6.1 19.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) UPF0560 PF10577.9 CDJ44774.1 - 0.087 11.3 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 AAA PF00004.29 CDJ44775.1 - 8.9e-07 29.4 0.0 1.1e-06 29.1 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RskA PF10099.9 CDJ44775.1 - 0.028 14.7 0.8 0.032 14.5 0.8 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ44777.1 - 7.2e-05 21.9 3.5 7.2e-05 21.9 3.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ44777.1 - 0.015 15.7 0.8 0.023 15.1 0.1 1.8 2 0 0 2 2 2 0 Enhancer of polycomb-like DDHD PF02862.17 CDJ44777.1 - 0.25 11.5 4.6 0.19 11.9 1.0 2.0 2 0 0 2 2 2 0 DDHD domain ALMT PF11744.8 CDJ44777.1 - 0.38 9.5 2.3 0.61 8.8 2.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 CDJ44777.1 - 0.38 8.6 2.8 0.58 8.0 2.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_F PF12259.8 CDJ44777.1 - 1.5 7.2 3.4 2 6.8 3.4 1.1 1 0 0 1 1 1 0 Baculovirus F protein Activator_LAG-3 PF11498.8 CDJ44777.1 - 7.8 5.3 34.3 0.66 8.9 25.5 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF2057 PF09829.9 CDJ44778.1 - 0.76 9.9 8.4 0.81 9.8 8.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) TFIIA PF03153.13 CDJ44778.1 - 1.8 8.5 11.6 2 8.3 11.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FSA_C PF10479.9 CDJ44778.1 - 1.9 6.6 5.1 2.1 6.4 5.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus MSP1_C PF07462.11 CDJ44778.1 - 1.9 7.1 2.9 2.2 6.9 2.9 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF4404 PF14357.6 CDJ44778.1 - 3 8.5 7.8 0.91 10.2 3.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Spt20 PF12090.8 CDJ44778.1 - 4.6 6.8 7.3 5.4 6.6 7.3 1.2 1 0 0 1 1 1 0 Spt20 family DUF3138 PF11336.8 CDJ44778.1 - 6.4 5.3 20.7 8.5 4.9 20.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SUIM_assoc PF16619.5 CDJ44779.1 - 0.0095 16.0 2.6 0.0095 16.0 2.6 3.5 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 OSCP PF00213.18 CDJ44779.1 - 0.026 14.6 0.2 0.081 13.0 0.2 1.8 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit HTH_Tnp_Tc3_2 PF01498.18 CDJ44779.1 - 0.034 14.4 0.3 0.073 13.3 0.3 1.5 1 0 0 1 1 1 0 Transposase EIF4E-T PF10477.9 CDJ44779.1 - 0.55 9.0 6.1 0.79 8.5 6.1 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF5521 PF17659.1 CDJ44780.1 - 0.087 10.7 0.1 0.15 9.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5521) CCDC53 PF10152.9 CDJ44780.1 - 4.5 7.7 8.9 5.7 7.3 4.1 3.0 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Roughex PF06020.11 CDJ44781.1 - 0.2 10.8 5.4 0.21 10.7 5.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 CDJ44781.1 - 0.3 10.7 7.5 0.29 10.7 7.5 1.0 1 0 0 1 1 1 0 Spt20 family PS_Dcarbxylase PF02666.15 CDJ44782.1 - 3.3e-16 59.4 0.0 3.9e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Spt20 PF12090.8 CDJ44783.1 - 0.11 12.1 15.7 0.055 13.1 5.9 2.1 2 0 0 2 2 2 0 Spt20 family DUF1043 PF06295.12 CDJ44783.1 - 1.6 8.7 13.8 0.063 13.3 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Lin-8 PF03353.15 CDJ44783.1 - 2.5 7.6 7.2 6.7 6.2 3.9 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist IMUP PF15761.5 CDJ44783.1 - 2.9 8.6 17.5 2.9 8.6 2.5 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF2722 PF10846.8 CDJ44783.1 - 6.5 5.6 16.5 1.6 7.6 8.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) WD40 PF00400.32 CDJ44784.1 - 2.3e-08 34.5 0.1 0.0063 17.3 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ44784.1 - 2.1e-05 24.7 0.0 0.023 15.0 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain SAPS PF04499.15 CDJ44785.1 - 4.6 5.9 6.1 4.8 5.9 6.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 CDJ44785.1 - 6.5 5.5 10.1 6.6 5.5 10.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 CDJ44785.1 - 6.7 5.8 24.0 7.3 5.7 24.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 CDJ44785.1 - 6.8 5.3 12.1 8.1 5.1 12.1 1.4 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CDJ44785.1 - 8.2 4.4 12.1 9.2 4.3 12.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TPR_12 PF13424.6 CDJ44786.1 - 5e-06 26.7 0.8 0.00059 20.1 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ44786.1 - 0.00049 19.9 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_3 PF07720.12 CDJ44786.1 - 0.03 14.3 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1387 PF07139.11 CDJ44788.1 - 0.44 10.2 11.4 0.58 9.8 11.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF3138 PF11336.8 CDJ44788.1 - 9.7 4.7 12.3 11 4.5 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Thioredoxin_6 PF13848.6 CDJ44790.1 - 0.00043 20.2 0.0 1.2 9.0 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin-like domain RNA_pol_Rbc25 PF08292.12 CDJ44793.1 - 3.4e-20 72.6 0.7 9e-09 35.7 0.4 2.8 2 1 0 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CDJ44793.1 - 5e-11 42.8 0.0 9.4e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CDJ44793.1 - 0.0054 17.0 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Ribosomal_60s PF00428.19 CDJ44793.1 - 0.028 15.0 8.9 0.048 14.3 8.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein MFS_1 PF07690.16 CDJ44794.1 - 0.0009 18.3 0.2 0.00099 18.1 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2722 PF10846.8 CDJ44794.1 - 0.0019 17.2 0.3 0.0019 17.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ44794.1 - 0.089 12.4 9.5 0.1 12.2 9.5 1.1 1 0 0 1 1 1 0 Spt20 family DivIC PF04977.15 CDJ44794.1 - 0.2 11.4 5.0 0.3 10.9 5.0 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF4834 PF16118.5 CDJ44794.1 - 0.35 11.9 3.0 0.7 10.9 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 CDJ44794.1 - 1.1 8.0 10.4 1.4 7.7 10.4 1.1 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 CDJ44794.1 - 1.3 8.9 9.2 1.5 8.7 9.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5321 PF17254.2 CDJ44795.1 - 0.017 14.6 7.0 0.017 14.6 7.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5321) PAT1 PF09770.9 CDJ44795.1 - 0.24 9.6 26.6 0.28 9.4 26.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MAT1 PF06391.13 CDJ44795.1 - 0.54 10.1 22.8 0.03 14.1 16.8 1.7 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 cwf18 PF08315.12 CDJ44795.1 - 0.56 10.9 15.7 0.41 11.3 12.9 2.0 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor RAP1 PF07218.11 CDJ44795.1 - 1.9 6.7 5.8 2.5 6.3 5.8 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4770 PF15994.5 CDJ44795.1 - 9.9 6.4 21.6 0.95 9.7 16.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) ATG16 PF08614.11 CDJ44799.1 - 0.07 13.3 29.5 0.26 11.5 28.7 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) RAP1 PF07218.11 CDJ44799.1 - 0.12 10.7 0.8 0.12 10.7 0.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 CDJ44799.1 - 0.29 10.7 18.1 0.42 10.2 18.1 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Atg14 PF10186.9 CDJ44799.1 - 0.34 10.0 22.0 0.44 9.6 22.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 IMUP PF15761.5 CDJ44799.1 - 0.65 10.7 9.9 1.2 9.9 9.9 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Seryl_tRNA_N PF02403.22 CDJ44799.1 - 0.9 9.8 17.2 0.36 11.1 0.7 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FAM76 PF16046.5 CDJ44799.1 - 2.6 7.3 13.8 3.3 7.0 13.8 1.2 1 0 0 1 1 1 0 FAM76 protein SOBP PF15279.6 CDJ44799.1 - 3.9 8.0 8.8 4.3 7.9 8.8 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein XhlA PF10779.9 CDJ44799.1 - 8.7 6.6 8.5 5.8 7.2 0.5 2.9 2 1 1 3 3 3 0 Haemolysin XhlA Methyltransf_25 PF13649.6 CDJ44800.1 - 5.9e-05 23.7 1.0 5.9e-05 23.7 1.0 2.6 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ44800.1 - 0.00053 19.8 0.6 0.00053 19.8 0.6 2.3 2 0 0 2 2 2 1 Methyltransferase domain Macoilin PF09726.9 CDJ44800.1 - 0.00066 18.4 0.3 0.00079 18.1 0.3 1.2 1 0 0 1 1 1 1 Macoilin family Methyltransf_23 PF13489.6 CDJ44800.1 - 0.003 17.4 0.0 0.003 17.4 0.0 2.7 2 1 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.19 CDJ44800.1 - 0.0089 16.2 1.9 0.01 16.0 0.1 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 CDJ44800.1 - 0.021 15.6 0.3 0.021 15.6 0.3 3.3 3 1 0 3 3 3 0 Methyltransferase domain NACHT PF05729.12 CDJ44800.1 - 0.092 12.7 7.2 0.023 14.6 2.4 2.5 3 1 1 4 4 4 0 NACHT domain DCAF15_WD40 PF14939.6 CDJ44800.1 - 0.099 12.3 1.4 0.21 11.2 1.4 1.5 1 1 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat Methyltransf_11 PF08241.12 CDJ44800.1 - 0.12 13.0 6.1 0.044 14.4 1.7 2.6 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 CDJ44800.1 - 0.18 11.7 1.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Peptidase_S64 PF08192.11 CDJ44800.1 - 0.61 8.5 8.9 0.76 8.2 8.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Band_3_cyto PF07565.13 CDJ44800.1 - 1.6 8.5 9.3 3 7.6 9.3 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain GREB1 PF15782.5 CDJ44800.1 - 1.9 5.5 10.9 2.4 5.2 10.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PrmA PF06325.13 CDJ44800.1 - 2.2 7.6 9.2 0.083 12.3 1.3 2.1 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) CSG2 PF16965.5 CDJ44800.1 - 7.1 5.5 5.0 9.5 5.0 5.0 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator SPT16 PF08644.11 CDJ44800.1 - 9 6.5 10.2 19 5.4 10.2 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) GIDA PF01134.22 CDJ44801.1 - 1.3e-21 77.1 1.8 1.6e-21 76.9 1.8 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A Ribosomal_60s PF00428.19 CDJ44801.1 - 1.3 9.6 8.9 0.077 13.6 3.1 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Androgen_recep PF02166.16 CDJ44803.1 - 0.26 10.1 2.5 0.27 10.0 2.5 1.1 1 0 0 1 1 1 0 Androgen receptor SUIM_assoc PF16619.5 CDJ44803.1 - 0.43 10.7 8.4 0.62 10.2 8.4 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2431 PF10354.9 CDJ44805.1 - 0.0029 17.9 0.0 0.003 17.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PP_kinase_C_1 PF17941.1 CDJ44805.1 - 0.0046 16.5 0.0 0.0057 16.2 0.0 1.1 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain 1 ubiquitin PF00240.23 CDJ44806.1 - 8.8e-18 63.8 0.2 9.3e-18 63.8 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ44806.1 - 7.6e-08 32.1 0.2 7.6e-08 32.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ44806.1 - 0.00019 21.8 0.4 0.0004 20.8 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 CDJ44806.1 - 0.0074 16.8 0.0 0.0083 16.7 0.0 1.0 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 CDJ44806.1 - 0.032 14.6 0.1 0.033 14.6 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain tRNA-synt_2d PF01409.20 CDJ44808.1 - 5.3e-30 104.7 0.1 5.9e-30 104.5 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) DUF2228 PF10228.9 CDJ44809.1 - 0.00035 20.4 0.0 0.00036 20.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) SBD_N PF07005.11 CDJ44810.1 - 0.079 12.7 0.1 0.079 12.7 0.1 2.1 2 0 0 2 2 2 0 Sugar-binding N-terminal domain GMC_oxred_C PF05199.13 CDJ44810.1 - 0.085 13.4 0.4 0.2 12.2 0.4 1.6 1 0 0 1 1 1 0 GMC oxidoreductase RR_TM4-6 PF06459.12 CDJ44810.1 - 0.21 11.4 7.1 0.23 11.2 7.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 CDJ44810.1 - 0.28 11.3 12.3 0.4 10.8 12.3 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF572 PF04502.13 CDJ44810.1 - 0.61 9.6 14.5 0.68 9.5 14.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SR-25 PF10500.9 CDJ44810.1 - 1.6 8.3 19.0 3.3 7.3 19.0 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_23 PF13476.6 CDJ44810.1 - 5 7.6 13.1 6.1 7.3 13.1 1.2 1 1 0 1 1 1 0 AAA domain DUF572 PF04502.13 CDJ44811.1 - 0.25 10.9 7.5 0.37 10.4 7.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hydrolase_4 PF12146.8 CDJ44812.1 - 0.001 18.4 0.0 1 8.6 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CDJ44812.1 - 0.0048 16.4 0.0 0.0072 15.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CDJ44812.1 - 0.0095 15.8 0.9 0.014 15.2 0.9 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 CDJ44812.1 - 0.03 13.7 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_2 PF02230.16 CDJ44812.1 - 0.034 13.9 0.1 0.16 11.7 0.0 2.0 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CDJ44812.1 - 0.16 12.6 11.4 0.015 15.9 6.3 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Ribosomal_60s PF00428.19 CDJ44812.1 - 4.4 8.0 26.8 0.53 10.9 4.3 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF3597 PF12200.8 CDJ44812.1 - 6.2 7.4 5.2 7.1 7.2 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) RskA PF10099.9 CDJ44812.1 - 8.8 6.6 16.7 7.8 6.7 3.7 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA TauE PF01925.19 CDJ44814.1 - 2.8e-12 46.8 7.3 2.8e-12 46.8 7.3 2.2 1 1 1 2 2 2 1 Sulfite exporter TauE/SafE TFIIA PF03153.13 CDJ44814.1 - 7.1 6.5 19.8 11 5.8 19.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GTP_EFTU_D2 PF03144.25 CDJ44815.1 - 0.00013 22.3 0.2 0.00025 21.4 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF2993 PF11209.8 CDJ44816.1 - 0.0028 17.9 0.1 0.0032 17.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2993) FAD-SLDH PF12318.8 CDJ44817.1 - 0.0075 16.3 3.0 0.0098 16.0 3.0 1.2 1 0 0 1 1 1 1 Membrane bound FAD containing D-sorbitol dehydrogenase PI3_PI4_kinase PF00454.27 CDJ44819.1 - 3.7e-28 99.0 0.0 7.1e-28 98.1 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CDJ44819.1 - 1.9e-12 46.8 0.0 3.8e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 FATC domain TAT_signal PF10518.9 CDJ44819.1 - 0.17 11.8 3.7 0.37 10.7 3.7 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence DUF4518 PF15008.6 CDJ44819.1 - 0.49 9.5 2.6 4.6 6.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) Spt20 PF12090.8 CDJ44820.1 - 0.13 11.8 7.9 0.14 11.8 7.9 1.0 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 CDJ44820.1 - 1.9 7.0 3.2 2 7.0 3.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hydrolase PF00702.26 CDJ44821.1 - 4.5e-12 46.7 0.0 8e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF3337 PF11816.8 CDJ44822.1 - 0.12 12.3 0.5 0.24 11.3 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) RasGEF PF00617.19 CDJ44822.1 - 0.19 11.9 0.0 6.1 7.0 0.0 2.4 2 0 0 2 2 2 0 RasGEF domain SAS-6_N PF16531.5 CDJ44823.1 - 3.1e-07 30.9 0.0 3.1e-07 30.9 0.0 3.6 3 3 0 3 3 3 1 Centriolar protein SAS N-terminal DUF1376 PF07120.11 CDJ44823.1 - 0.083 13.2 1.6 1.4 9.3 2.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) DAGAT PF03982.13 CDJ44824.1 - 1.8e-45 155.1 0.0 2.1e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase CCDC144C PF14915.6 CDJ44825.1 - 0.93 8.5 54.7 0.4 9.8 29.3 2.7 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region IFT57 PF10498.9 CDJ44825.1 - 8.9 5.2 39.2 3.1 6.7 12.7 2.6 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Golgin_A5 PF09787.9 CDJ44825.1 - 8.9 5.7 58.8 1.5 8.3 13.0 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 SAGA-Tad1 PF12767.7 CDJ44828.1 - 0.016 14.9 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit T2SSM_b PF10741.9 CDJ44828.1 - 0.41 10.5 2.2 0.64 9.8 0.0 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b PAT1 PF09770.9 CDJ44829.1 - 3.5 5.8 15.6 4.6 5.4 15.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2722 PF10846.8 CDJ44830.1 - 0.0025 16.8 1.5 0.0025 16.8 1.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) ASFV_J13L PF05568.11 CDJ44833.1 - 0.18 11.5 3.4 0.41 10.4 3.4 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein Bax1-I PF01027.20 CDJ44834.1 - 0.00011 22.1 0.4 0.00012 22.0 0.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF1007 PF06226.13 CDJ44835.1 - 0.055 13.4 2.2 0.078 13.0 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) DUF3523 PF12037.8 CDJ44835.1 - 1.2 8.4 20.9 1.4 8.3 20.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Androgen_recep PF02166.16 CDJ44835.1 - 1.6 7.5 7.6 1.9 7.2 7.6 1.1 1 0 0 1 1 1 0 Androgen receptor Macoilin PF09726.9 CDJ44835.1 - 8.1 4.9 17.2 9 4.7 17.2 1.1 1 0 0 1 1 1 0 Macoilin family DHC_N2 PF08393.13 CDJ44837.1 - 2.8e-23 82.7 0.0 6.3e-23 81.5 0.0 1.4 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 HisKA_3 PF07730.13 CDJ44837.1 - 0.0027 18.2 1.7 0.11 13.1 0.0 3.5 2 2 2 4 4 4 1 Histidine kinase ABC_tran_CTD PF16326.5 CDJ44837.1 - 0.015 15.5 2.5 0.015 15.5 2.5 3.2 4 0 0 4 4 4 0 ABC transporter C-terminal domain GntR PF00392.21 CDJ44837.1 - 0.054 13.2 0.5 7.3 6.3 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family PilJ PF13675.6 CDJ44837.1 - 0.06 13.4 1.8 0.47 10.5 0.0 2.8 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Alkyl_sulf_C PF14864.6 CDJ44837.1 - 0.094 13.0 0.2 0.8 10.0 0.0 2.4 3 0 0 3 3 3 0 Alkyl sulfatase C-terminal Baculo_PEP_C PF04513.12 CDJ44837.1 - 0.096 12.7 0.3 0.096 12.7 0.3 2.8 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L37e PF01907.19 CDJ44838.1 - 5.9e-26 90.4 12.5 5.9e-26 90.4 12.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L37e SelR PF01641.18 CDJ44838.1 - 0.0032 17.5 1.3 0.0042 17.2 0.8 1.5 1 1 1 2 2 2 1 SelR domain DZR PF12773.7 CDJ44838.1 - 0.061 13.4 1.1 0.061 13.4 1.1 1.5 2 0 0 2 2 2 0 Double zinc ribbon DUF1462 PF07315.11 CDJ44838.1 - 0.11 12.8 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) SR-25 PF10500.9 CDJ44839.1 - 0.0077 15.9 1.4 0.0081 15.8 1.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CSG2 PF16965.5 CDJ44839.1 - 0.012 14.5 0.1 0.014 14.4 0.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Dehydrin PF00257.19 CDJ44839.1 - 0.12 12.9 0.4 0.15 12.6 0.4 1.2 1 0 0 1 1 1 0 Dehydrin TFIIA PF03153.13 CDJ44839.1 - 0.37 10.7 3.1 0.44 10.5 3.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit O-FucT PF10250.9 CDJ44840.1 - 1.1e-15 58.2 0.0 9.7e-15 55.1 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF2722 PF10846.8 CDJ44840.1 - 5.4e-05 22.3 38.1 0.0053 15.8 3.7 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF2722) RNase_H2_suC PF08615.11 CDJ44840.1 - 0.14 12.4 2.5 26 5.0 0.0 3.1 3 0 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FHIPEP PF00771.20 CDJ44840.1 - 0.18 10.2 20.4 0.024 13.1 4.5 3.1 3 0 0 3 3 3 0 FHIPEP family HemX PF04375.14 CDJ44840.1 - 0.42 9.8 46.8 0.16 11.2 6.9 3.4 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase EPL1 PF10513.9 CDJ44840.1 - 0.53 10.7 14.8 4.3 7.7 0.4 3.4 3 0 0 3 3 3 0 Enhancer of polycomb-like PRC2_HTH_1 PF18118.1 CDJ44840.1 - 1.4 9.8 9.3 8.2 7.3 0.3 3.5 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain DUF1676 PF07898.13 CDJ44840.1 - 1.5 8.8 4.0 0.64 10.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) MecA PF05389.12 CDJ44840.1 - 3.7 7.1 14.1 1 8.9 0.5 3.1 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) TPR_1 PF00515.28 CDJ44843.1 - 2e-20 71.7 7.5 7.1e-07 28.8 0.1 5.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ44843.1 - 5e-17 60.6 15.8 9.9e-06 25.3 0.1 6.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ44843.1 - 2.7e-14 52.6 5.7 1.8e-06 27.5 0.1 6.2 2 2 3 6 6 6 2 TPR repeat TPR_19 PF14559.6 CDJ44843.1 - 1.3e-10 41.6 18.0 3.9e-05 24.1 0.4 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ44843.1 - 2.5e-10 39.7 1.6 0.00024 21.0 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ44843.1 - 4.2e-10 40.1 26.1 2.1e-06 28.3 0.7 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ44843.1 - 1.8e-08 34.5 21.8 0.058 14.2 0.0 7.4 5 1 3 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ44843.1 - 1.4e-07 31.4 13.3 0.0023 18.2 0.2 6.4 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ44843.1 - 2.1e-07 31.0 0.6 6.8e-06 26.1 0.2 4.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ44843.1 - 6.6e-06 26.3 18.8 0.017 15.4 1.6 4.9 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ44843.1 - 3e-05 23.7 9.8 0.086 12.9 0.1 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ44843.1 - 0.00016 21.9 4.9 0.7 10.2 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 CDJ44843.1 - 1.2 9.6 17.2 0.89 10.0 7.4 3.2 3 0 0 3 3 3 0 Bacterial transcriptional activator domain DUF3209 PF11483.8 CDJ44843.1 - 5.5 7.5 8.8 6.2 7.3 0.5 3.4 4 1 0 4 4 3 0 Protein of unknown function (DUF3209) TPR_10 PF13374.6 CDJ44843.1 - 6.4 6.8 14.7 1.3 8.9 0.3 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.14 CDJ44844.1 - 5.2e-06 25.9 0.0 5.5e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CDJ44844.1 - 0.02 15.3 0.0 0.021 15.3 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 CDJ44844.1 - 0.023 14.9 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 CDJ44844.1 - 0.072 11.9 0.0 0.084 11.7 0.0 1.0 1 0 0 1 1 1 0 Tryptophan halogenase Alpha-amylase PF00128.24 CDJ44845.1 - 0.25 10.9 0.0 0.42 10.1 0.0 1.2 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Peptidase_M3 PF01432.20 CDJ44846.1 - 0.0051 16.1 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF3437 PF11919.8 CDJ44847.1 - 1.9e-27 95.0 0.0 2.5e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Choline_kinase PF01633.20 CDJ44848.1 - 5.6e-19 68.6 0.0 6.6e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CDJ44848.1 - 2.3e-10 40.8 0.0 2.4e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CDJ44848.1 - 0.0009 18.6 0.0 0.001 18.4 0.0 1.0 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 CDJ44848.1 - 0.055 12.3 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF2722 PF10846.8 CDJ44849.1 - 0.73 8.7 9.6 0.5 9.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF2722 PF10846.8 CDJ44850.1 - 0.0011 18.0 8.8 0.0011 18.0 8.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) GxGYxYP_C PF14323.6 CDJ44850.1 - 0.056 13.3 0.5 0.069 13.0 0.5 1.2 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain Atypical_Card PF18461.1 CDJ44850.1 - 0.23 11.7 2.7 0.71 10.1 2.7 1.8 1 1 0 1 1 1 0 Atypical caspase recruitment domain Presenilin PF01080.17 CDJ44850.1 - 0.36 9.5 2.7 0.36 9.5 2.7 1.2 1 0 0 1 1 1 0 Presenilin Het-C PF07217.11 CDJ44850.1 - 0.7 8.3 4.9 0.75 8.3 4.9 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Ndc1_Nup PF09531.10 CDJ44850.1 - 0.76 8.4 7.1 0.87 8.2 7.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ORC_WH_C PF18137.1 CDJ44850.1 - 0.91 9.6 6.7 0.23 11.6 3.6 1.6 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal EphA2_TM PF14575.6 CDJ44850.1 - 4.2 8.3 6.1 3.2 8.7 3.3 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Neur_chan_memb PF02932.16 CDJ44850.1 - 5.6 6.9 10.0 7.1 6.6 10.0 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CDJ44850.1 - 5.9 6.8 20.0 6.7 6.6 10.4 2.3 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) GTP1_OBG PF01018.22 CDJ44851.1 - 0.049 13.2 2.3 0.1 12.2 2.3 1.6 1 0 0 1 1 1 0 GTP1/OBG Ras PF00071.22 CDJ44852.1 - 3.3e-20 72.3 0.0 4.6e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ44852.1 - 0.017 15.3 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Cpn60_TCP1 PF00118.24 CDJ44853.1 - 8.4e-30 103.8 0.1 1.1e-29 103.5 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RFC1 PF08519.12 CDJ44854.1 - 4.5e-17 62.6 0.0 5.6e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain CorA PF01544.18 CDJ44855.1 - 2.8e-05 23.6 4.5 0.013 14.9 2.9 2.6 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Gly-zipper_OmpA PF13436.6 CDJ44855.1 - 0.0073 16.1 21.2 0.017 14.9 0.7 3.5 2 1 1 3 3 3 2 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 CDJ44855.1 - 0.0086 15.8 6.2 0.0086 15.8 6.2 3.4 2 1 1 3 3 3 1 YMGG-like Gly-zipper DUF1218 PF06749.12 CDJ44855.1 - 0.034 14.6 1.8 0.48 11.0 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) PT PF04886.12 CDJ44855.1 - 0.53 9.9 19.5 2.8 7.6 5.4 4.1 3 2 0 3 3 3 0 PT repeat TPR_2 PF07719.17 CDJ44856.1 - 1.4e-10 40.4 15.8 2.6e-05 24.0 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ44856.1 - 5.5e-09 36.4 16.8 0.0035 17.8 0.6 4.2 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ44856.1 - 1.4e-07 31.0 10.7 0.00019 21.1 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ44856.1 - 7.2e-06 25.8 0.5 0.0066 16.6 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ44856.1 - 4.7e-05 23.6 20.5 0.16 12.2 5.4 5.0 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ44856.1 - 0.00024 20.7 0.2 0.39 10.4 0.0 3.0 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 CDJ44856.1 - 0.00072 20.2 25.2 0.05 14.4 1.0 5.6 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ44856.1 - 0.00073 20.1 32.0 0.0073 16.9 11.8 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ44856.1 - 0.0035 17.5 11.3 0.037 14.2 3.8 4.0 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3446 PF11928.8 CDJ44856.1 - 0.0073 16.6 10.0 0.018 15.3 10.0 1.6 1 0 0 1 1 1 1 Early growth response N-terminal domain TPR_7 PF13176.6 CDJ44856.1 - 0.031 14.3 10.4 6.5 7.0 0.0 6.0 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ44856.1 - 0.036 14.5 5.3 0.77 10.3 0.0 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 CDJ44856.1 - 0.065 13.3 3.3 0.067 13.3 0.5 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TPR_6 PF13174.6 CDJ44856.1 - 0.55 11.0 10.4 5.7 7.8 0.0 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ44857.1 - 5.1e-09 35.6 6.3 0.0073 16.1 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ44857.1 - 9.5e-07 28.5 6.4 0.021 14.9 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ44857.1 - 2.3e-06 27.2 5.5 0.0033 17.1 0.1 3.7 3 0 0 3 3 3 2 TPR repeat SUIM_assoc PF16619.5 CDJ44857.1 - 0.012 15.6 0.0 0.012 15.6 0.0 4.1 3 1 1 4 4 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2951 PF11166.8 CDJ44857.1 - 0.047 13.9 0.3 0.047 13.9 0.3 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF2951) TPR_8 PF13181.6 CDJ44857.1 - 0.096 13.0 3.3 1.1 9.6 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ44857.1 - 0.13 12.7 3.7 3.8 8.1 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Pex14_N PF04695.13 CDJ44857.1 - 0.13 12.9 11.8 0.26 11.9 11.8 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_6 PF13174.6 CDJ44857.1 - 0.38 11.5 3.3 23 5.9 0.1 4.5 3 1 1 4 4 3 0 Tetratricopeptide repeat ALMT PF11744.8 CDJ44857.1 - 0.68 8.7 14.6 0.2 10.4 9.4 1.9 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF913 PF06025.12 CDJ44857.1 - 0.84 8.6 6.2 1.3 7.9 6.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoVR PF04293.13 CDJ44857.1 - 0.87 8.2 13.8 0.23 10.1 10.5 1.6 2 0 0 2 2 2 0 SpoVR like protein Zip PF02535.22 CDJ44857.1 - 1.3 8.2 3.2 1.3 8.1 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PIEZO PF15917.5 CDJ44857.1 - 3.7 7.0 19.5 0.14 11.7 13.8 1.5 2 0 0 2 2 2 0 Piezo Vfa1 PF08432.10 CDJ44857.1 - 5.1 7.4 22.0 1.5 9.1 15.6 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF789 PF05623.12 CDJ44857.1 - 5.6 6.6 11.1 3 7.4 9.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF789) Hydin_ADK PF17213.3 CDJ44857.1 - 8.3 6.6 11.4 5.1 7.3 9.6 1.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Rrn6 PF10214.9 CDJ44858.1 - 2.6e-05 23.0 5.2 2.7e-05 22.9 5.2 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor UPF0542 PF15086.6 CDJ44858.1 - 0.11 12.5 0.6 0.33 10.9 0.3 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Myb_DNA-binding PF00249.31 CDJ44859.1 - 2.5e-05 24.4 0.2 3.6e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ44859.1 - 0.0093 16.2 0.1 0.0093 16.2 0.1 1.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 CDJ44859.1 - 0.096 12.7 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 SLIDE SUIM_assoc PF16619.5 CDJ44859.1 - 1.4 9.0 9.1 1.8 8.7 9.1 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 NUDE_C PF04880.13 CDJ44860.1 - 0.0013 19.2 4.8 0.0014 19.2 4.8 1.0 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region MTBP_C PF14920.6 CDJ44860.1 - 0.34 10.6 5.1 0.36 10.5 5.1 1.0 1 0 0 1 1 1 0 MDM2-binding Spt20 PF12090.8 CDJ44860.1 - 0.37 10.4 7.3 0.39 10.3 7.3 1.1 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ44860.1 - 0.46 10.6 12.6 0.75 9.9 12.6 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Herpes_UL74 PF07982.12 CDJ44860.1 - 0.64 8.9 2.2 0.7 8.8 2.2 1.0 1 0 0 1 1 1 0 Herpes UL74 glycoproteins TFIIA PF03153.13 CDJ44860.1 - 0.73 9.8 8.3 0.88 9.5 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4813 PF16072.5 CDJ44860.1 - 0.75 9.4 15.5 0.71 9.5 15.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) BRCT PF00533.26 CDJ44861.1 - 1.8e-05 25.0 0.0 2.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PAF PF15715.5 CDJ44861.1 - 0.13 12.8 7.7 0.19 12.3 7.7 1.3 1 0 0 1 1 1 0 PCNA-associated factor histone like domain DUF4680 PF15730.5 CDJ44861.1 - 0.24 11.8 5.3 0.27 11.6 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) SR-25 PF10500.9 CDJ44861.1 - 0.34 10.5 9.5 0.35 10.4 9.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 CDJ44861.1 - 1.6 7.2 6.3 1.6 7.2 6.3 1.0 1 0 0 1 1 1 0 Macoilin family DUF3104 PF11302.8 CDJ44864.1 - 0.003 17.2 0.2 0.0042 16.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3104) RRM_1 PF00076.22 CDJ44867.1 - 5.5e-10 38.9 0.0 1e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ44867.1 - 1.2e-07 31.5 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CDJ44867.1 - 1.9e-07 30.7 0.0 2.4e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 CDJ44867.1 - 0.046 13.6 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Limkain-b1 PF11608.8 CDJ44867.1 - 0.088 12.9 0.0 0.12 12.4 0.0 1.3 1 1 0 1 1 1 0 Limkain b1 TMEM214 PF10151.9 CDJ44868.1 - 0.0042 15.6 0.0 0.005 15.4 0.0 1.1 1 0 0 1 1 1 1 TMEM214, C-terminal, caspase 4 activator FAM27 PF15832.5 CDJ44868.1 - 0.014 15.9 0.1 0.031 14.8 0.1 1.5 2 0 0 2 2 2 0 FAM27 D and E protein family DUF5423 PF17461.2 CDJ44868.1 - 0.16 10.8 7.4 0.22 10.3 7.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Actin PF00022.19 CDJ44869.1 - 6.2e-13 48.1 0.0 8e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 Actin MIF4G_like_2 PF09090.11 CDJ44870.1 - 1.4e-09 37.9 2.2 1.4e-09 37.9 0.0 1.8 1 1 0 2 2 2 1 MIF4G like Methyltransf_32 PF13679.6 CDJ44871.1 - 0.038 14.0 0.1 0.038 14.0 0.1 1.6 2 0 0 2 2 2 0 Methyltransferase domain Met_synt_B12 PF02965.17 CDJ44871.1 - 0.069 12.6 0.4 0.099 12.1 0.4 1.2 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain Spt20 PF12090.8 CDJ44871.1 - 0.84 9.2 11.6 1.4 8.4 11.6 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ44871.1 - 5.4 6.9 14.0 7.5 6.4 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ44876.1 - 0.15 12.0 10.7 0.95 9.4 4.4 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Proteasome PF00227.26 CDJ44877.1 - 2.5e-19 69.5 0.1 3.2e-19 69.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit V-ATPase_H_N PF03224.14 CDJ44878.1 - 1.2e-07 31.3 0.0 1.4e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit H DNA_pol_A_exo1 PF01612.20 CDJ44879.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 3'-5' exonuclease NUDIX PF00293.28 CDJ44880.1 - 5.7e-06 26.4 0.0 8.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Secretin_N_2 PF07655.13 CDJ44880.1 - 0.64 10.6 10.0 1.2 9.7 10.0 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain UPAR_LY6_2 PF16975.5 CDJ44880.1 - 0.85 9.8 5.4 13 6.0 0.2 2.2 2 0 0 2 2 2 0 Ly6/PLAUR domain-containing protein 6, Lypd6 DUF2722 PF10846.8 CDJ44881.1 - 2.3e-05 23.5 0.8 2.3e-05 23.5 0.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ44881.1 - 0.00042 20.7 3.9 0.049 14.0 0.0 2.1 2 0 0 2 2 2 2 Enhancer of polycomb-like RskA PF10099.9 CDJ44881.1 - 0.0014 18.9 2.6 0.0014 18.9 2.6 4.2 2 2 2 4 4 4 2 Anti-sigma-K factor rskA NABP PF07990.12 CDJ44881.1 - 0.026 14.1 1.1 0.026 14.1 1.1 2.0 2 0 0 2 2 2 0 Nucleic acid binding protein NABP Apc15p PF05841.11 CDJ44881.1 - 0.036 14.9 2.5 0.036 14.9 2.5 2.5 2 0 0 2 2 2 0 Apc15p protein EOS1 PF12326.8 CDJ44881.1 - 0.075 13.0 3.7 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 N-glycosylation protein DDHD PF02862.17 CDJ44881.1 - 0.093 12.9 7.1 1.5 9.0 0.8 2.2 2 0 0 2 2 2 0 DDHD domain V_ATPase_I PF01496.19 CDJ44881.1 - 0.16 9.9 4.5 0.25 9.2 4.5 1.2 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Activator_LAG-3 PF11498.8 CDJ44881.1 - 2.9 6.7 47.4 3.6 6.5 20.4 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 CPSF100_C PF13299.6 CDJ44881.1 - 3.2 7.9 11.8 1.6 8.9 3.2 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PAT1 PF09770.9 CDJ44881.1 - 5.3 5.2 25.4 0.53 8.5 7.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 CDJ44881.1 - 5.7 5.5 13.8 1.3 7.6 1.9 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Spt20 PF12090.8 CDJ44881.1 - 7.1 6.2 39.9 5.6 6.5 12.7 2.2 2 0 0 2 2 2 0 Spt20 family Presenilin PF01080.17 CDJ44881.1 - 7.2 5.3 10.6 2.9 6.5 3.6 2.0 2 0 0 2 2 2 0 Presenilin Exonuc_VII_L PF02601.15 CDJ44881.1 - 8.4 5.9 19.2 0.96 8.9 6.6 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Symplekin_C PF12295.8 CDJ44882.1 - 0.018 15.2 4.5 0.033 14.3 4.5 1.5 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal TFIIA PF03153.13 CDJ44882.1 - 0.018 15.0 12.2 0.019 15.0 12.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 7TM_GPCR_Srv PF10323.9 CDJ44882.1 - 0.72 9.2 1.8 1.1 8.5 1.8 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv FAD-SLDH PF12318.8 CDJ44882.1 - 0.92 9.6 9.6 41 4.2 9.2 2.1 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase tRNA_bind_2 PF13725.6 CDJ44882.1 - 1 9.0 13.6 1.6 8.3 13.6 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain Phage_GPO PF05929.11 CDJ44882.1 - 1.1 8.8 10.2 1.4 8.4 10.2 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Presenilin PF01080.17 CDJ44882.1 - 3.2 6.4 5.4 3.6 6.2 5.4 1.1 1 0 0 1 1 1 0 Presenilin Collagen PF01391.18 CDJ44884.1 - 0.0023 17.6 26.9 0.0097 15.6 26.9 2.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Spt20 PF12090.8 CDJ44884.1 - 1.1 8.8 16.0 0.019 14.6 4.1 2.4 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 CDJ44884.1 - 7.9 6.6 24.2 0.58 10.3 9.0 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 KH_1 PF00013.29 CDJ44886.1 - 1.6e-05 24.6 0.4 3.2e-05 23.7 0.4 1.4 1 0 0 1 1 1 1 KH domain Hist_deacetyl PF00850.19 CDJ44887.1 - 5.5e-06 26.1 0.0 6.1e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain zf-dskA_traR PF01258.17 CDJ44888.1 - 0.13 12.2 4.1 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger DNA_RNApol_7kD PF03604.13 CDJ44888.1 - 0.66 9.7 6.0 4.3 7.1 0.1 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Pkinase PF00069.25 CDJ44890.1 - 3.2e-10 39.8 0.0 4.1e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ44890.1 - 0.00028 20.3 0.0 0.00036 19.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Peripla_BP_3 PF13377.6 CDJ44891.1 - 0.0096 16.3 0.5 0.0096 16.3 0.5 2.1 1 1 1 2 2 2 1 Periplasmic binding protein-like domain DUF2615 PF11027.8 CDJ44891.1 - 0.56 10.4 5.8 0.89 9.7 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) Ribosomal_60s PF00428.19 CDJ44891.1 - 1.1 9.9 15.2 0.78 10.4 10.9 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ44891.1 - 2.4 8.1 10.4 3.7 7.5 10.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 CDJ44893.1 - 0.0059 16.4 9.5 0.0064 16.2 9.5 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF4776 PF16003.5 CDJ44893.1 - 0.018 14.1 4.0 0.026 13.5 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Aminopep PF10023.9 CDJ44893.1 - 0.045 13.1 1.0 0.069 12.5 1.0 1.2 1 0 0 1 1 1 0 Putative aminopeptidase IATP PF04568.12 CDJ44893.1 - 0.092 13.2 6.5 0.031 14.7 3.2 1.9 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Tmemb_cc2 PF10267.9 CDJ44893.1 - 0.27 10.3 17.3 0.39 9.8 17.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SPX PF03105.19 CDJ44893.1 - 0.77 9.6 24.7 0.94 9.3 24.7 1.2 1 0 0 1 1 1 0 SPX domain DUF1373 PF07117.11 CDJ44893.1 - 0.89 9.5 23.4 1.1 9.3 23.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) SOG2 PF10428.9 CDJ44893.1 - 1 8.5 24.5 1.2 8.3 24.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SOBP PF15279.6 CDJ44893.1 - 1.8 9.1 17.4 2.4 8.7 17.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein MAP70 PF07058.11 CDJ44893.1 - 2.4 6.8 13.8 3 6.5 13.8 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 Raftlin PF15250.6 CDJ44893.1 - 3 6.5 11.0 3.6 6.2 11.0 1.1 1 0 0 1 1 1 0 Raftlin PAP1 PF08601.10 CDJ44893.1 - 3.1 7.4 25.1 3.5 7.2 25.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Apt1 PF10351.9 CDJ44893.1 - 5.1 5.8 23.1 6.7 5.5 23.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Roughex PF06020.11 CDJ44893.1 - 5.4 6.0 9.7 4 6.4 8.4 1.4 1 1 0 1 1 1 0 Drosophila roughex protein Hid1 PF12722.7 CDJ44893.1 - 6.5 4.7 15.0 6.8 4.7 15.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Hamartin PF04388.12 CDJ44893.1 - 7.2 5.1 16.6 8.4 4.9 16.6 1.0 1 0 0 1 1 1 0 Hamartin protein Peptidase_S64 PF08192.11 CDJ44893.1 - 7.7 4.9 20.4 8.6 4.7 20.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 FAM76 PF16046.5 CDJ44893.1 - 7.8 5.8 12.1 11 5.3 12.1 1.2 1 0 0 1 1 1 0 FAM76 protein TPR_19 PF14559.6 CDJ44894.1 - 3.2e-11 43.6 4.5 0.00012 22.5 0.2 5.3 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ44894.1 - 4.5e-09 35.8 1.7 0.019 15.2 0.2 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ44894.1 - 6e-08 32.9 24.0 0.019 15.7 0.0 7.3 4 3 3 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ44894.1 - 3.7e-07 29.7 1.1 0.048 13.5 0.3 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ44894.1 - 3.7e-05 23.5 14.9 0.0017 18.3 0.3 6.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ44894.1 - 0.00015 21.8 13.5 0.12 12.5 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ44894.1 - 0.0008 19.0 7.2 3 7.6 0.3 4.0 5 0 0 5 5 5 3 TPR repeat TPR_17 PF13431.6 CDJ44894.1 - 0.00082 19.6 0.1 7 7.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ44894.1 - 0.057 13.7 0.1 0.057 13.7 0.1 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ44894.1 - 0.47 11.2 8.3 0.47 11.2 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 CDJ44894.1 - 4.7 7.7 5.0 1.1e+02 3.4 0.1 3.7 3 0 0 3 3 3 0 PPR repeat SOBP PF15279.6 CDJ44896.1 - 0.03 14.9 23.6 0.037 14.7 23.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Activator_LAG-3 PF11498.8 CDJ44896.1 - 0.17 10.8 41.9 0.24 10.4 41.9 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Tmemb_14 PF03647.13 CDJ44896.1 - 0.22 12.3 1.6 0.62 10.8 1.6 1.7 2 0 0 2 2 2 0 Transmembrane proteins 14C DUF4148 PF13663.6 CDJ44896.1 - 0.94 9.7 13.7 4.2 7.6 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) PAT1 PF09770.9 CDJ44896.1 - 1.3 7.2 27.4 1.4 7.1 27.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ44896.1 - 2.3 8.0 19.3 2.9 7.6 19.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_22 PF13401.6 CDJ44897.1 - 0.023 15.0 0.1 0.023 15.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain TraI_2_C PF07515.11 CDJ44897.1 - 0.15 12.0 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term Hexokinase_2 PF03727.16 CDJ44897.1 - 0.25 10.7 1.8 0.28 10.6 1.8 1.1 1 0 0 1 1 1 0 Hexokinase SET PF00856.28 CDJ44898.1 - 0.021 15.2 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 SET domain PerC PF06069.11 CDJ44898.1 - 0.038 14.3 0.8 0.063 13.5 0.8 1.3 1 0 0 1 1 1 0 PerC transcriptional activator XTBD PF11952.8 CDJ44898.1 - 0.083 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD HemX PF04375.14 CDJ44899.1 - 0.011 15.0 24.4 0.013 14.8 24.4 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase PA26 PF04636.13 CDJ44899.1 - 0.02 13.8 9.4 0.023 13.6 9.4 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hydin_ADK PF17213.3 CDJ44899.1 - 0.098 12.9 15.2 0.12 12.6 15.2 1.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF445 PF04286.12 CDJ44899.1 - 0.16 11.8 6.0 0.16 11.7 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) GREB1 PF15782.5 CDJ44899.1 - 0.88 6.6 15.1 0.95 6.5 15.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FliP PF00813.20 CDJ44899.1 - 0.97 9.3 5.5 1.1 9.1 5.5 1.2 1 0 0 1 1 1 0 FliP family TFIIA PF03153.13 CDJ44899.1 - 1.2 9.1 32.3 1.3 8.9 32.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_C13 PF01650.18 CDJ44899.1 - 1.2 8.6 8.4 1.7 8.1 8.4 1.2 1 0 0 1 1 1 0 Peptidase C13 family Peptidase_S49_N PF08496.10 CDJ44899.1 - 1.2 9.1 9.2 1.6 8.8 9.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3533 PF12051.8 CDJ44899.1 - 1.8 7.4 10.8 2.7 6.8 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Cellulose_synt PF03552.14 CDJ44899.1 - 2.4 6.5 7.0 2.4 6.5 7.0 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF1758 PF05585.12 CDJ44899.1 - 2.5 7.9 9.6 8 6.2 4.5 1.8 1 1 1 2 2 2 0 Putative peptidase (DUF1758) DUF4844 PF16133.5 CDJ44899.1 - 3.5 8.2 7.1 9.9 6.7 7.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4844) Exonuc_VII_L PF02601.15 CDJ44899.1 - 3.8 7.0 15.5 4.1 6.9 15.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit ALMT PF11744.8 CDJ44899.1 - 4.1 6.1 10.0 4.5 6.0 10.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Lin-8 PF03353.15 CDJ44899.1 - 4.9 6.6 18.0 5.7 6.4 18.0 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Endonuc_Holl PF10107.9 CDJ44899.1 - 5.2 6.9 9.0 6.9 6.5 9.0 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase LCIB_C_CA PF18599.1 CDJ44899.1 - 5.3 6.3 11.6 6.5 6.0 11.6 1.1 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases PAT1 PF09770.9 CDJ44899.1 - 7.6 4.7 22.8 8.1 4.6 22.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ZYG-11_interact PF05884.12 CDJ44899.1 - 8 5.8 10.2 10 5.4 10.2 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 Phage_GPO PF05929.11 CDJ44899.1 - 8.4 5.9 15.7 10 5.6 15.7 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Cob_adeno_trans PF01923.18 CDJ44901.1 - 0.005 17.0 0.6 0.0082 16.3 0.6 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF4407 PF14362.6 CDJ44901.1 - 0.0085 15.5 5.2 0.012 15.0 5.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Adap_comp_sub PF00928.21 CDJ44902.1 - 1.5e-13 50.7 0.0 1.8e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family BAF1_ABF1 PF04684.13 CDJ44903.1 - 5.3 6.0 10.0 6.5 5.7 10.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF5521 PF17659.1 CDJ44903.1 - 7.4 4.3 7.4 9.1 4.0 7.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) RAD51_interact PF15696.5 CDJ44904.1 - 0.025 14.7 0.3 0.29 11.2 0.0 2.4 2 0 0 2 2 2 0 RAD51 interacting motif GpcrRhopsn4 PF10192.9 CDJ44906.1 - 3.7e-07 29.8 1.3 5e-07 29.4 1.3 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 CDJ44906.1 - 0.00026 20.3 1.0 0.00033 20.0 1.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor TMCCDC2 PF15844.5 CDJ44906.1 - 0.94 9.4 4.4 1.2 9.0 0.5 2.2 1 1 1 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 Mg_trans_NIPA PF05653.14 CDJ44907.1 - 2e-13 50.1 5.7 2.3e-13 49.9 5.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CDJ44907.1 - 4.7e-06 26.8 6.1 4.7e-06 26.8 6.1 2.2 2 1 0 2 2 2 1 EamA-like transporter family CCDC14 PF15254.6 CDJ44908.1 - 0.27 9.9 3.7 0.44 9.2 3.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 TFIIF_alpha PF05793.12 CDJ44910.1 - 0.0034 16.1 9.5 0.0034 16.1 9.5 1.6 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 CDJ44910.1 - 9.1 4.4 16.4 2.2 6.5 10.6 2.1 2 0 0 2 2 2 0 CDC45-like protein RabGAP-TBC PF00566.18 CDJ44911.1 - 0.00019 21.2 0.3 0.00019 21.2 0.3 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SUIM_assoc PF16619.5 CDJ44911.1 - 0.0029 17.6 1.4 0.0029 17.6 1.4 3.6 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 CDJ44911.1 - 0.015 14.1 5.7 0.024 13.4 5.7 1.3 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ44911.1 - 0.17 10.6 8.0 0.21 10.2 8.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EIIBC-GUT_N PF03612.14 CDJ44911.1 - 0.7 9.6 5.6 0.24 11.1 0.3 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus BRF1 PF07741.13 CDJ44911.1 - 2.5 8.5 11.9 3.2 8.2 2.9 3.1 3 0 0 3 3 3 0 Brf1-like TBP-binding domain DUF2971 PF11185.8 CDJ44911.1 - 3.9 8.7 5.7 1.7e+02 3.5 8.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2971) DUF2897 PF11446.8 CDJ44912.1 - 0.19 11.6 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) YSIRK_signal PF04650.17 CDJ44912.1 - 0.53 10.2 5.0 0.91 9.4 5.0 1.4 1 0 0 1 1 1 0 YSIRK type signal peptide RRM_1 PF00076.22 CDJ44913.1 - 1.2e-09 37.9 0.1 1.8e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ44913.1 - 6.7e-06 25.7 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ44913.1 - 4.2e-05 23.3 0.0 6.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CDJ44913.1 - 0.032 14.2 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Peptidase_Mx PF15887.5 CDJ44913.1 - 0.26 10.6 0.0 0.38 10.1 0.0 1.1 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase DUF913 PF06025.12 CDJ44918.1 - 1.9 7.4 4.8 3.5 6.5 4.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SR-25 PF10500.9 CDJ44918.1 - 2.6 7.6 17.5 1.9 8.1 4.6 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 CDJ44919.1 - 0.024 12.9 9.2 0.029 12.7 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Cas_CT1975 PF09344.10 CDJ44919.1 - 0.058 12.8 2.8 0.1 12.0 2.8 1.4 1 0 0 1 1 1 0 CT1975-like protein RIX1 PF08167.12 CDJ44919.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis DNA_pol_phi PF04931.13 CDJ44919.1 - 0.27 9.3 8.9 0.36 8.9 8.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Myc_N PF01056.18 CDJ44919.1 - 0.72 9.7 6.9 5.5 6.8 5.9 2.0 2 0 0 2 2 2 0 Myc amino-terminal region PTPRCAP PF15713.5 CDJ44919.1 - 2 8.7 14.9 0.18 12.1 10.0 1.7 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Astro_capsid_p PF12226.8 CDJ44919.1 - 6.6 5.8 6.9 10 5.2 6.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DnaJ PF00226.31 CDJ44921.1 - 5.6e-16 58.4 0.3 1.4e-15 57.2 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain Fasciclin PF02469.22 CDJ44922.1 - 7.1e-08 32.7 0.2 0.0031 17.7 0.0 3.3 3 0 0 3 3 3 2 Fasciclin domain DUF1645 PF07816.11 CDJ44922.1 - 3.8 8.1 11.3 0.12 13.0 3.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) TFIIA PF03153.13 CDJ44922.1 - 5 7.0 17.5 1.8 8.5 12.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ44923.1 - 0.025 14.6 5.0 0.029 14.4 3.9 1.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TAF PF02969.17 CDJ44923.1 - 0.039 14.1 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Spt20 PF12090.8 CDJ44923.1 - 0.91 9.1 6.5 1.1 8.8 6.5 1.1 1 0 0 1 1 1 0 Spt20 family DNA_pol_A_exo1 PF01612.20 CDJ44924.1 - 1.6e-17 63.7 0.0 1.6e-11 44.2 0.0 2.1 2 0 0 2 2 2 2 3'-5' exonuclease Apt1 PF10351.9 CDJ44924.1 - 0.0034 16.3 18.7 0.004 16.1 18.7 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain SAPS PF04499.15 CDJ44924.1 - 0.0096 14.8 3.9 0.012 14.4 3.9 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein SOG2 PF10428.9 CDJ44924.1 - 0.018 14.3 20.2 0.02 14.1 20.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 CDJ44924.1 - 0.021 13.6 8.4 0.027 13.3 8.4 1.2 1 0 0 1 1 1 0 Presenilin Utp14 PF04615.13 CDJ44924.1 - 0.032 12.8 7.0 0.034 12.7 7.0 1.1 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.10 CDJ44924.1 - 0.053 12.9 15.5 0.078 12.3 15.5 1.2 1 0 0 1 1 1 0 BUD22 PNISR PF15996.5 CDJ44924.1 - 0.06 13.6 7.7 0.08 13.2 7.7 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CCDC84 PF14968.6 CDJ44924.1 - 0.073 12.7 6.2 0.1 12.2 6.2 1.3 1 0 0 1 1 1 0 Coiled coil protein 84 SPX PF03105.19 CDJ44924.1 - 0.36 10.7 24.7 0.5 10.2 24.7 1.1 1 0 0 1 1 1 0 SPX domain Peptidase_S64 PF08192.11 CDJ44924.1 - 0.52 8.7 15.4 0.56 8.6 15.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 TFIIF_alpha PF05793.12 CDJ44924.1 - 1.7 7.2 14.9 1.9 7.0 14.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PI3K_1B_p101 PF10486.9 CDJ44924.1 - 1.7 6.3 12.6 2 6.1 12.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Neur_chan_memb PF02932.16 CDJ44924.1 - 1.9 8.5 5.9 2.8 7.9 5.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.13 CDJ44924.1 - 2.5 6.8 13.8 4.3 6.0 13.8 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Mucin PF01456.17 CDJ44924.1 - 2.7 8.0 22.2 4 7.4 22.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein GREB1 PF15782.5 CDJ44924.1 - 3.3 4.7 15.8 3.9 4.5 15.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 CDJ44924.1 - 3.7 6.9 11.7 6 6.2 11.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Sec3_C PF09763.9 CDJ44924.1 - 4.6 5.5 10.7 8.3 4.7 10.7 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec3 SLC12 PF03522.15 CDJ44924.1 - 6.7 5.6 9.2 9.1 5.2 9.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIIAH PF12685.7 CDJ44924.1 - 7 6.4 19.7 12 5.6 19.7 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein EGF_3 PF12947.7 CDJ44925.1 - 6.1 7.1 9.4 3.1 8.1 5.6 2.1 1 1 1 2 2 2 0 EGF domain AP3D1 PF06375.11 CDJ44926.1 - 0.027 14.7 9.3 0.028 14.7 9.3 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 FAM176 PF14851.6 CDJ44926.1 - 0.15 11.7 2.5 0.16 11.6 2.5 1.1 1 0 0 1 1 1 0 FAM176 family Pex14_N PF04695.13 CDJ44926.1 - 0.16 12.6 18.3 0.2 12.3 18.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hydin_ADK PF17213.3 CDJ44926.1 - 0.43 10.8 6.2 0.44 10.8 6.2 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF4175 PF13779.6 CDJ44926.1 - 0.45 8.4 25.4 0.44 8.4 25.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Presenilin PF01080.17 CDJ44926.1 - 0.51 9.0 8.6 0.46 9.2 8.6 1.1 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 CDJ44926.1 - 0.74 9.2 8.7 0.73 9.2 8.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Connexin PF00029.19 CDJ44926.1 - 0.82 9.4 6.6 0.9 9.3 6.6 1.1 1 0 0 1 1 1 0 Connexin TMEM51 PF15345.6 CDJ44926.1 - 0.86 9.4 8.7 1 9.2 8.7 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 eIF-3_zeta PF05091.12 CDJ44926.1 - 1.3 8.0 12.8 1.2 8.0 12.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Tho2 PF11262.8 CDJ44926.1 - 1.5 7.9 10.9 1.7 7.8 10.9 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TFIIA PF03153.13 CDJ44926.1 - 1.6 8.7 29.4 1.7 8.6 29.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Plasmodium_Vir PF05795.11 CDJ44926.1 - 1.6 8.1 4.8 1.5 8.1 4.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SID-1_RNA_chan PF13965.6 CDJ44926.1 - 2.4 6.5 3.8 2.5 6.4 3.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CDJ44926.1 - 2.4 8.2 5.7 2.3 8.2 5.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ44926.1 - 4.1 6.3 7.5 4.5 6.2 7.5 1.0 1 0 0 1 1 1 0 CLN3 protein Ctr PF04145.15 CDJ44926.1 - 4.1 8.0 5.7 4.3 8.0 5.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family PAT1 PF09770.9 CDJ44926.1 - 4.9 5.3 19.4 4.6 5.4 19.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0560 PF10577.9 CDJ44926.1 - 6.6 5.1 18.5 7.2 5.0 18.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Suf PF05843.14 CDJ44926.1 - 7 6.5 14.4 7.1 6.5 14.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CrgA PF06781.12 CDJ44926.1 - 8.9 6.4 6.2 23 5.1 4.5 2.4 1 1 1 2 2 2 0 Cell division protein CrgA Med15 PF09606.10 CDJ44926.1 - 9.3 4.8 28.0 9.6 4.7 28.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ44927.1 - 0.0055 16.8 4.3 0.0055 16.8 4.3 3.1 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit SOBP PF15279.6 CDJ44927.1 - 0.14 12.7 35.5 0.12 12.9 27.4 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Macoilin PF09726.9 CDJ44927.1 - 6 5.3 20.5 0.0069 15.0 5.2 2.1 2 0 0 2 2 2 0 Macoilin family Rad51 PF08423.11 CDJ44928.1 - 3.6e-14 52.6 2.4 2.4e-11 43.4 2.8 3.1 2 1 0 2 2 2 2 Rad51 AAA_25 PF13481.6 CDJ44928.1 - 3.1e-06 26.9 0.2 3.1e-06 26.9 0.2 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CDJ44928.1 - 0.00076 19.4 3.1 0.019 14.9 3.1 2.3 1 1 0 1 1 1 1 NACHT domain RecA PF00154.21 CDJ44928.1 - 0.033 13.6 0.4 0.37 10.2 0.2 2.2 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_33 PF13671.6 CDJ44928.1 - 0.035 14.3 2.6 0.18 11.9 0.0 2.7 2 1 1 3 3 3 0 AAA domain CobU PF02283.16 CDJ44928.1 - 0.052 13.1 0.4 0.63 9.6 0.1 2.4 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase RecC_C PF17946.1 CDJ44928.1 - 0.38 10.5 10.1 0.059 13.1 4.2 2.5 1 1 2 3 3 3 0 RecC C-terminal domain Viral_P18 PF04521.13 CDJ44929.1 - 0.07 12.9 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Spt20 PF12090.8 CDJ44929.1 - 1.4 8.5 64.7 0.2 11.2 21.8 3.3 3 0 0 3 3 3 0 Spt20 family PCI PF01399.27 CDJ44932.1 - 0.1 13.1 0.0 0.85 10.2 0.0 2.1 2 0 0 2 2 2 0 PCI domain Phostensin_N PF13916.6 CDJ44933.1 - 0.78 10.1 10.8 0.73 10.2 2.1 2.7 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Auto_anti-p27 PF06677.12 CDJ44934.1 - 8.7e-17 61.0 2.1 1.4e-16 60.3 2.1 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) SUIM_assoc PF16619.5 CDJ44934.1 - 8.4e-05 22.6 14.9 0.012 15.7 4.7 2.4 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 CNDH2_M PF16869.5 CDJ44934.1 - 0.011 16.4 6.5 0.37 11.5 0.5 2.2 1 1 1 2 2 2 0 PF16858 Spt20 PF12090.8 CDJ44934.1 - 0.15 11.6 18.4 0.058 13.0 7.7 2.1 2 0 0 2 2 2 0 Spt20 family Presenilin PF01080.17 CDJ44934.1 - 1.3 7.8 10.5 1.4 7.6 10.5 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ44934.1 - 3.6 8.6 11.7 1.5 9.8 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) M_domain PF12938.7 CDJ44934.1 - 3.9 7.2 21.7 4.4 7.0 4.1 2.1 2 0 0 2 2 2 0 M domain of GW182 OATP PF03137.20 CDJ44935.1 - 0.00041 18.8 0.0 0.00053 18.4 0.0 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family ATG16 PF08614.11 CDJ44936.1 - 0.0094 16.2 32.5 0.014 15.6 32.5 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CDJ44936.1 - 0.016 14.1 25.9 0.02 13.8 25.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TFIIA PF03153.13 CDJ44936.1 - 0.78 9.7 20.6 0.91 9.4 20.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLC12 PF03522.15 CDJ44936.1 - 1.5 7.8 8.7 1.9 7.4 8.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 CDJ44936.1 - 9.3 5.0 10.9 11 4.8 10.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 CDJ44936.1 - 9.3 4.0 13.5 11 3.7 13.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SR-25 PF10500.9 CDJ44937.1 - 0.077 12.6 8.4 0.088 12.4 8.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DAGK_acc PF00609.19 CDJ44940.1 - 3.7e-15 56.6 0.0 5e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CDJ44940.1 - 5.5e-10 38.9 0.1 5.1e-08 32.6 0.1 2.7 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Spond_N PF06468.13 CDJ44940.1 - 0.19 11.8 0.0 0.48 10.5 0.0 1.6 1 0 0 1 1 1 0 Spondin_N CALCOCO1 PF07888.11 CDJ44941.1 - 0.013 14.4 0.4 0.014 14.3 0.4 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3138 PF11336.8 CDJ44941.1 - 0.56 8.8 7.5 0.57 8.7 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) GSH_synth_ATP PF03917.17 CDJ44942.1 - 2e-29 102.5 0.0 1.9e-13 49.9 0.0 3.0 3 0 0 3 3 3 3 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CDJ44942.1 - 1.5e-18 67.1 0.0 2.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase PmbA_TldD PF01523.16 CDJ44942.1 - 0.016 15.0 0.0 0.028 14.3 0.0 1.5 1 1 0 1 1 1 0 Putative modulator of DNA gyrase DUF3446 PF11928.8 CDJ44942.1 - 7.6 6.9 15.6 0.91 9.9 0.3 4.1 2 1 1 4 4 4 0 Early growth response N-terminal domain PCI PF01399.27 CDJ44944.1 - 6.5e-11 42.7 0.4 2e-10 41.1 0.4 1.8 1 1 0 1 1 1 1 PCI domain DUF3038 PF11237.8 CDJ44944.1 - 0.004 17.2 1.3 0.0063 16.6 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3038) CENP-O PF09496.10 CDJ44944.1 - 0.052 13.5 0.1 0.15 12.0 0.1 1.7 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component SARAF PF06682.12 CDJ44944.1 - 0.056 13.1 0.2 0.07 12.8 0.2 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis hGDE_central PF14702.6 CDJ44944.1 - 0.066 12.9 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme SR-25 PF10500.9 CDJ44944.1 - 0.08 12.5 8.7 0.18 11.4 8.7 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1699 PF08004.11 CDJ44944.1 - 0.14 11.8 0.7 0.92 9.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) FAM199X PF15814.5 CDJ44944.1 - 0.22 10.6 7.4 0.058 12.4 4.8 1.3 1 1 0 1 1 1 0 Protein family FAM199X AF-4 PF05110.13 CDJ44944.1 - 0.55 8.3 7.3 0.73 7.8 7.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein IMUP PF15761.5 CDJ44944.1 - 0.59 10.9 6.9 1 10.1 6.9 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein TMEM51 PF15345.6 CDJ44944.1 - 0.67 9.8 6.5 1.2 8.9 6.0 1.6 1 1 1 2 2 2 0 Transmembrane protein 51 Fis1_TPR_C PF14853.6 CDJ44946.1 - 2.2e-05 24.4 0.5 2.2e-05 24.4 0.5 3.4 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 CDJ44946.1 - 8.4e-05 22.6 2.2 0.00011 22.3 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ44946.1 - 0.0019 17.9 11.0 0.0062 16.3 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 CDJ44946.1 - 0.0064 16.5 1.5 0.0064 16.5 1.5 3.2 3 1 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 CDJ44946.1 - 0.0066 16.5 10.9 0.0084 16.1 0.1 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ44946.1 - 0.019 15.6 0.4 0.019 15.6 0.4 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Vps39_2 PF10367.9 CDJ44946.1 - 0.32 11.5 3.0 1.9 9.0 0.0 3.0 3 1 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 TPR_12 PF13424.6 CDJ44946.1 - 0.63 10.4 7.1 4.9 7.5 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ44946.1 - 0.96 9.8 10.2 2.4 8.6 0.1 4.9 3 1 1 5 5 5 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 CDJ44947.1 - 0.099 12.7 6.3 0.18 11.9 6.3 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CLTH PF10607.9 CDJ44949.1 - 2.5e-08 33.9 0.0 3e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain N6_N4_Mtase PF01555.18 CDJ44950.1 - 0.047 13.4 0.0 3.2 7.4 0.0 3.3 3 1 0 3 3 3 0 DNA methylase Adaptin_binding PF10199.9 CDJ44950.1 - 0.48 11.0 0.0 0.48 11.0 0.0 2.5 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 CCDC53 PF10152.9 CDJ44950.1 - 0.54 10.7 27.0 1.7 9.1 1.2 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex FAM91_C PF14648.6 CDJ44950.1 - 0.71 8.6 8.7 3.8 6.3 0.0 2.3 2 0 0 2 2 2 0 FAM91 C-terminus LMBR1 PF04791.16 CDJ44950.1 - 3.3 6.5 10.0 6.5 5.5 10.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.11 CDJ44950.1 - 8.8 4.7 25.2 14 4.1 25.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein CAF1C_H4-bd PF12265.8 CDJ44951.1 - 9.2e-10 38.7 0.0 1.8e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Phage_GPO PF05929.11 CDJ44951.1 - 0.022 14.4 0.7 0.026 14.1 0.7 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase PIEZO PF15917.5 CDJ44951.1 - 0.065 12.7 2.8 0.076 12.5 2.8 1.1 1 0 0 1 1 1 0 Piezo Nop25 PF09805.9 CDJ44951.1 - 0.21 12.0 8.7 0.27 11.7 8.7 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF4746 PF15928.5 CDJ44951.1 - 0.91 8.9 6.6 1.1 8.6 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 CDJ44951.1 - 6.6 5.4 5.6 7.6 5.2 5.6 1.0 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 CDJ44951.1 - 6.8 5.9 9.7 9.8 5.4 9.7 1.3 1 0 0 1 1 1 0 NOA36 protein Raffinose_syn PF05691.12 CDJ44953.1 - 0.00034 18.6 0.4 0.00072 17.5 0.1 1.6 2 0 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 HGTP_anticodon PF03129.20 CDJ44954.1 - 2e-16 59.9 4.8 2.6e-16 59.6 0.0 3.3 4 0 0 4 4 4 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CDJ44954.1 - 1.4e-09 38.2 1.4 2.8e-08 33.9 1.4 2.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Pkinase PF00069.25 CDJ44955.1 - 0.00025 20.5 0.0 0.00028 20.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Shisa PF13908.6 CDJ44956.1 - 0.00023 21.4 12.5 0.00035 20.9 12.5 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SR-25 PF10500.9 CDJ44956.1 - 0.00099 18.8 3.9 0.00099 18.8 3.9 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein SID-1_RNA_chan PF13965.6 CDJ44956.1 - 0.0084 14.6 2.7 0.011 14.2 2.7 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 TFIIA PF03153.13 CDJ44956.1 - 0.01 15.8 17.7 0.012 15.7 17.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CBP_BcsG PF11658.8 CDJ44956.1 - 0.013 13.9 2.2 0.019 13.4 2.2 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG SelP_N PF04592.14 CDJ44956.1 - 0.055 12.9 23.4 0.091 12.2 23.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3464 PF11947.8 CDJ44956.1 - 0.11 12.2 2.5 0.087 12.6 0.4 1.9 1 1 0 2 2 2 0 Photosynthesis affected mutant 68 V_ATPase_I PF01496.19 CDJ44956.1 - 0.16 9.8 4.3 0.2 9.5 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GREB1 PF15782.5 CDJ44956.1 - 0.54 7.3 13.5 0.73 6.9 13.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Serinc PF03348.15 CDJ44956.1 - 0.6 9.0 5.7 0.79 8.6 5.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ilar_coat PF01787.16 CDJ44956.1 - 1.6 8.5 7.2 5 6.9 0.6 2.2 2 0 0 2 2 2 0 Ilarvirus coat protein Tmemb_9 PF05434.11 CDJ44956.1 - 3.7 7.4 8.1 12 5.7 8.2 1.8 1 1 0 1 1 1 0 TMEM9 EOS1 PF12326.8 CDJ44956.1 - 3.8 7.4 13.6 2.3 8.1 11.4 1.7 1 1 1 2 2 2 0 N-glycosylation protein bZIP_C PF12498.8 CDJ44956.1 - 4.8 8.2 20.0 0.31 12.0 10.6 2.3 2 0 0 2 2 2 0 Basic leucine-zipper C terminal Zip PF02535.22 CDJ44956.1 - 5.8 6.0 19.7 2.5 7.2 17.4 1.5 1 1 1 2 2 2 0 ZIP Zinc transporter SUIM_assoc PF16619.5 CDJ44957.1 - 0.0074 16.3 4.2 0.013 15.5 4.2 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 M_domain PF12938.7 CDJ44958.1 - 0.0015 18.4 5.1 0.3 10.8 4.5 2.1 2 0 0 2 2 2 2 M domain of GW182 Spt20 PF12090.8 CDJ44958.1 - 1.4 8.5 5.4 1.8 8.1 5.4 1.1 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ44958.1 - 2.5 8.3 10.0 4.5 7.4 10.0 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 HAP1_N PF04849.13 CDJ44959.1 - 0.029 13.6 4.4 0.045 13.0 4.4 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Spc7 PF08317.11 CDJ44959.1 - 0.1 11.5 4.3 0.14 11.0 4.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HOOK PF05622.12 CDJ44959.1 - 0.16 10.1 3.2 0.22 9.6 3.2 1.1 1 0 0 1 1 1 0 HOOK protein DUF4763 PF15960.5 CDJ44959.1 - 2 7.7 6.7 3.9 6.7 6.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) CoA_transf_3 PF02515.17 CDJ44960.1 - 0.016 14.3 2.5 0.019 14.1 2.5 1.2 1 0 0 1 1 1 0 CoA-transferase family III Pox_F11 PF04943.12 CDJ44960.1 - 3 6.8 4.7 4 6.4 4.2 1.6 2 0 0 2 2 2 0 Poxvirus F11 protein SUIM_assoc PF16619.5 CDJ44960.1 - 3.8 7.7 22.4 0.34 11.0 7.8 3.3 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 S1 PF00575.23 CDJ44961.1 - 3.2e-11 43.4 0.1 2.4e-06 27.8 0.0 3.9 3 1 0 3 3 3 2 S1 RNA binding domain S1_2 PF13509.6 CDJ44961.1 - 0.0064 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 S1 domain Dehydrin PF00257.19 CDJ44962.1 - 0.0093 16.5 2.6 0.011 16.3 2.6 1.2 1 0 0 1 1 1 1 Dehydrin ARA70 PF12489.8 CDJ44962.1 - 0.099 12.8 1.1 0.14 12.4 1.1 1.1 1 0 0 1 1 1 0 Nuclear coactivator SAP18 PF06487.12 CDJ44963.1 - 5.7e-29 101.1 0.0 1e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) CDC50 PF03381.15 CDJ44967.1 - 5.5e-21 75.3 2.2 5.8e-21 75.2 0.0 1.8 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF104 PF01954.16 CDJ44969.1 - 0.0056 17.1 2.3 0.021 15.3 0.9 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF104 Moulting_cycle PF04870.16 CDJ44969.1 - 0.026 13.8 0.5 0.031 13.6 0.5 1.0 1 0 0 1 1 1 0 Moulting cycle ArdA PF07275.11 CDJ44969.1 - 0.089 13.4 2.6 2 9.0 0.1 2.0 1 1 1 2 2 2 0 Antirestriction protein (ArdA) SNAP-25 PF00835.19 CDJ44969.1 - 0.14 12.4 1.3 0.25 11.7 1.3 1.3 1 0 0 1 1 1 0 SNAP-25 family Carb_anhydrase PF00194.21 CDJ44970.1 - 4.8e-25 88.6 0.0 1.7e-22 80.2 0.1 2.9 1 1 1 2 2 2 2 Eukaryotic-type carbonic anhydrase Redoxin PF08534.10 CDJ44970.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Redoxin Baculo_LEF-2 PF03041.14 CDJ44970.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 lef-2 RskA PF10099.9 CDJ44970.1 - 0.95 9.7 14.3 0.025 14.9 1.2 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF3458 PF11940.8 CDJ44971.1 - 7.3e-07 29.6 0.1 1.2e-06 28.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold IMUP PF15761.5 CDJ44971.1 - 0.0001 22.9 9.2 0.00017 22.3 9.2 1.3 1 0 0 1 1 1 1 Immortalisation up-regulated protein Macoilin PF09726.9 CDJ44971.1 - 0.0059 15.2 3.1 0.0058 15.3 3.1 1.0 1 0 0 1 1 1 1 Macoilin family DUF4614 PF15391.6 CDJ44971.1 - 0.044 13.8 7.5 0.056 13.4 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Tcp11 PF05794.13 CDJ44971.1 - 0.048 12.8 1.2 0.053 12.6 1.2 1.1 1 0 0 1 1 1 0 T-complex protein 11 AF-4 PF05110.13 CDJ44971.1 - 0.063 11.4 16.3 0.073 11.2 16.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Peptidase_M1 PF01433.20 CDJ44971.1 - 0.079 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M1 domain GREB1 PF15782.5 CDJ44971.1 - 0.094 9.8 2.8 0.1 9.7 2.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Apt1 PF10351.9 CDJ44971.1 - 0.11 11.4 3.6 0.099 11.5 3.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ATP11 PF06644.11 CDJ44971.1 - 0.13 12.0 0.3 0.14 11.9 0.3 1.1 1 0 0 1 1 1 0 ATP11 protein TRP PF06011.12 CDJ44971.1 - 0.2 10.4 1.0 0.24 10.1 1.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel RSRP PF17069.5 CDJ44971.1 - 0.35 10.4 23.7 0.43 10.1 23.7 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CCDC24 PF15669.5 CDJ44971.1 - 0.44 10.4 4.7 0.5 10.2 4.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Corona_nucleoca PF00937.18 CDJ44971.1 - 2.6 7.0 10.8 2.9 6.8 10.8 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RAP1 PF07218.11 CDJ44971.1 - 2.9 6.1 12.6 3.1 6.0 12.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SDP_N PF12278.8 CDJ44971.1 - 4.6 7.4 6.6 7.6 6.7 6.6 1.5 1 0 0 1 1 1 0 Sex determination protein N terminal Sec3_C PF09763.9 CDJ44971.1 - 5.6 5.2 5.9 6.5 5.0 5.9 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF515 PF04415.12 CDJ44971.1 - 8 4.7 11.8 8.5 4.6 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Period_C PF12114.8 CDJ44971.1 - 9.5 5.8 16.7 32 4.0 17.6 1.4 2 0 0 2 2 2 0 Period protein 2/3C-terminal region LSM PF01423.22 CDJ44974.1 - 1.6e-22 79.0 0.0 1.8e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDJ44974.1 - 0.00075 19.6 0.0 0.00094 19.3 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 CDJ44974.1 - 0.059 13.0 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Nic96 PF04097.14 CDJ44976.1 - 0.17 10.3 0.2 0.19 10.2 0.2 1.0 1 0 0 1 1 1 0 Nup93/Nic96 V-SNARE_C PF12352.8 CDJ44977.1 - 0.0065 16.7 0.9 0.016 15.5 0.9 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 CDJ44977.1 - 0.042 14.2 0.4 0.13 12.6 0.4 1.8 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Phage_GPD PF05954.11 CDJ44977.1 - 1.2 8.4 6.3 4.9 6.4 6.3 1.8 1 1 0 1 1 1 0 Phage late control gene D protein (GPD) LSM PF01423.22 CDJ44978.1 - 2.2e-16 59.3 0.0 2.6e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ntox1 PF15500.6 CDJ44979.1 - 0.0011 19.2 1.2 0.014 15.7 1.2 3.0 1 0 0 1 1 1 1 Putative RNase-like toxin, toxin_1 Gag_p10 PF02337.17 CDJ44979.1 - 0.11 12.5 0.2 0.4 10.7 0.2 1.9 1 0 0 1 1 1 0 Retroviral GAG p10 protein BatD PF13584.6 CDJ44979.1 - 0.49 9.2 5.7 1.7 7.4 0.3 2.6 2 0 0 2 2 2 0 Oxygen tolerance p25-alpha PF05517.12 CDJ44980.1 - 1.2e-31 109.9 0.1 1.7e-31 109.5 0.1 1.3 1 1 0 1 1 1 1 p25-alpha Spt20 PF12090.8 CDJ44981.1 - 5.3 6.6 16.7 5.1 6.6 16.7 1.0 1 0 0 1 1 1 0 Spt20 family Histone PF00125.24 CDJ44982.1 - 2.6e-15 56.9 0.0 3.1e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 CDJ44982.1 - 0.00023 21.6 0.0 0.00037 20.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 CDJ44982.1 - 0.00099 19.4 0.1 0.0018 18.5 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GEN1_C PF18380.1 CDJ44983.1 - 0.21 12.5 1.7 23 5.9 0.5 2.7 3 0 0 3 3 3 0 Holliday junction resolvase Gen1 C-terminal domain DUF4718 PF15842.5 CDJ44983.1 - 5.5 6.7 15.7 0.67 9.7 4.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) TraT PF05818.12 CDJ44984.1 - 0.0048 16.6 6.0 0.0048 16.6 6.0 2.5 1 1 2 3 3 3 1 Enterobacterial TraT complement resistance protein Med15 PF09606.10 CDJ44984.1 - 0.12 11.1 43.5 0.13 10.9 43.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.12 CDJ44984.1 - 1.2 8.9 25.0 1.9 8.3 25.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4045 PF13254.6 CDJ44984.1 - 1.8 8.1 26.2 2.4 7.7 26.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RIFIN PF02009.16 CDJ44984.1 - 1.9 8.3 20.0 2.5 7.9 20.0 1.1 1 0 0 1 1 1 0 Rifin GREB1 PF15782.5 CDJ44984.1 - 2.2 5.3 23.1 2.6 5.0 23.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCSAP PF15748.5 CDJ44984.1 - 3 7.9 28.7 5 7.2 28.7 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Lin-8 PF03353.15 CDJ44984.1 - 6.8 6.1 29.9 8.7 5.8 29.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ44984.1 - 7.1 5.1 20.1 11 4.4 20.1 1.3 1 0 0 1 1 1 0 Macoilin family DUF4551 PF15087.6 CDJ44984.1 - 9.2 5.0 20.8 11 4.7 20.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Spt20 PF12090.8 CDJ44985.1 - 6.3 6.3 45.3 0.32 10.6 5.5 4.3 4 0 0 4 4 4 0 Spt20 family Mito_carr PF00153.27 CDJ44986.1 - 0.00013 21.8 1.1 0.00014 21.7 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial carrier protein NAM-associated PF14303.6 CDJ44988.1 - 0.0066 17.2 5.5 0.0066 17.2 5.5 3.5 2 1 1 3 3 3 1 No apical meristem-associated C-terminal domain EPL1 PF10513.9 CDJ44988.1 - 3.6 7.9 14.5 0.74 10.2 9.0 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like SUIM_assoc PF16619.5 CDJ44989.1 - 0.026 14.6 2.2 0.026 14.6 2.2 4.2 1 1 2 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Jnk-SapK_ap_N PF09744.9 CDJ44989.1 - 0.29 11.4 35.0 0.089 13.0 23.9 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF3274 PF11678.8 CDJ44989.1 - 0.31 10.2 5.6 0.048 12.9 1.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3274) Prominin PF05478.11 CDJ44989.1 - 4.8 5.0 15.5 6 4.7 15.5 1.3 1 0 0 1 1 1 0 Prominin PP2C PF00481.21 CDJ44990.1 - 2.1e-06 27.6 3.2 0.0089 15.7 0.0 3.1 3 2 1 4 4 4 2 Protein phosphatase 2C PAT1 PF09770.9 CDJ44990.1 - 5.1 5.2 34.0 7 4.8 34.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.25 CDJ44991.1 - 1.1e-68 231.5 0.0 1.2e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ44991.1 - 1.6e-34 119.4 0.0 1.8e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ44991.1 - 0.00014 21.0 0.0 0.0015 17.6 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDJ44991.1 - 0.0015 17.9 0.0 0.0034 16.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDJ44991.1 - 0.0051 16.8 0.1 0.0085 16.0 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ44991.1 - 0.0056 16.1 0.1 0.013 14.8 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CDJ44991.1 - 0.014 14.9 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-RanBP PF00641.18 CDJ44992.1 - 0.0012 18.1 8.1 0.0022 17.2 8.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others MAGE_N PF12440.8 CDJ44993.1 - 4.9 7.9 20.4 5.6 7.7 20.4 1.1 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal DLIC PF05783.11 CDJ44993.1 - 9.7 4.9 6.7 10 4.8 6.7 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RskA PF10099.9 CDJ44995.1 - 0.048 13.9 1.5 0.064 13.6 1.5 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA RRM_1 PF00076.22 CDJ44996.1 - 2.1e-48 162.0 0.1 3.1e-16 59.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ44996.1 - 9e-09 35.3 0.1 0.028 14.5 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif WW PF00397.26 CDJ44996.1 - 6.1e-05 23.0 0.9 0.00012 22.1 0.9 1.5 1 0 0 1 1 1 1 WW domain RNA_bind PF08675.11 CDJ44996.1 - 0.05 13.6 0.0 2.4 8.2 0.0 3.1 3 1 0 3 3 3 0 RNA binding domain ELH PF02323.15 CDJ44997.1 - 0.049 13.0 1.4 0.047 13.1 1.4 1.1 1 0 0 1 1 1 0 Egg-laying hormone precursor Guanylate_cyc PF00211.20 CDJ44999.1 - 3.7e-39 134.2 0.0 5.1e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ribosomal_60s PF00428.19 CDJ45002.1 - 8.4 7.1 7.6 0.76 10.4 2.3 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4667 PF15700.5 CDJ45003.1 - 0.00013 22.2 2.3 0.053 13.6 1.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4667) SNF2_N PF00176.23 CDJ45003.1 - 0.0034 16.1 0.0 0.0049 15.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Ribosomal_60s PF00428.19 CDJ45003.1 - 0.044 14.4 1.3 0.044 14.4 1.3 4.7 3 1 0 3 3 3 0 60s Acidic ribosomal protein SPX PF03105.19 CDJ45003.1 - 0.17 11.8 2.4 0.32 10.9 2.4 1.4 1 1 0 1 1 1 0 SPX domain Endostatin PF06482.11 CDJ45003.1 - 0.21 11.0 3.8 0.45 9.9 3.8 1.5 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CCDC53 PF10152.9 CDJ45003.1 - 1.7 9.1 4.1 3.3 8.1 0.2 2.9 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex RskA PF10099.9 CDJ45006.1 - 0.00049 20.4 8.8 0.00058 20.2 8.8 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF1180 PF06679.12 CDJ45006.1 - 1.1 9.6 4.2 1.4 9.3 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CAP_N PF01213.19 CDJ45006.1 - 2.7 7.4 7.4 3.6 7.0 7.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Phage_holin_3_3 PF16083.5 CDJ45006.1 - 2.7 8.1 5.4 4.1 7.6 0.2 2.2 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III DEC-1_N PF04625.13 CDJ45006.1 - 4.6 6.1 13.5 5.3 5.9 13.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DXPR_C PF13288.6 CDJ45008.1 - 2.4e-28 98.7 0.3 1.8e-25 89.4 0.3 2.2 1 1 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 CDJ45008.1 - 4e-10 39.7 0.3 1e-09 38.4 0.1 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DUF4383 PF14325.6 CDJ45009.1 - 0.077 13.3 2.2 0.19 12.0 2.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) DUF1206 PF06724.11 CDJ45009.1 - 0.14 12.2 3.2 0.6 10.2 0.4 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) Rod-binding PF10135.9 CDJ45011.1 - 0.15 12.7 0.2 0.32 11.6 0.2 1.7 1 0 0 1 1 1 0 Rod binding protein DOT1 PF08123.13 CDJ45012.1 - 0.00028 20.5 0.0 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 PrmA PF06325.13 CDJ45012.1 - 0.0037 16.7 0.0 0.0037 16.7 0.0 2.4 2 1 1 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) Adeno_E3 PF06040.11 CDJ45012.1 - 0.066 13.4 0.4 0.5 10.5 0.0 2.6 2 0 0 2 2 2 0 Adenovirus E3 protein DUF2714 PF10896.8 CDJ45012.1 - 0.093 12.8 0.2 0.25 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2714) eIF3_N PF09440.10 CDJ45012.1 - 0.1 13.0 17.4 0.12 12.8 6.7 2.9 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Guanylate_cyc PF00211.20 CDJ45013.1 - 1e-70 237.1 0.1 2.7e-35 121.7 1.4 3.8 2 2 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Hydrolase PF00702.26 CDJ45013.1 - 0.00044 20.6 0.1 0.011 16.0 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDJ45013.1 - 0.0018 17.8 0.0 0.26 10.8 0.0 3.0 2 0 0 2 2 2 2 E1-E2 ATPase RPA43_OB PF17875.1 CDJ45014.1 - 0.098 13.3 0.2 0.97 10.1 0.0 2.5 2 1 0 2 2 2 0 RPA43 OB domain in RNA Pol I BLOC1S3 PF15753.5 CDJ45014.1 - 0.11 12.7 1.1 0.44 10.7 1.0 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 ARID PF01388.21 CDJ45015.1 - 1.4e-12 48.1 0.0 1.4e-12 48.1 0.0 2.7 2 1 1 3 3 3 1 ARID/BRIGHT DNA binding domain Transket_pyr PF02779.24 CDJ45016.1 - 2.1e-58 196.9 0.1 7.7e-58 195.1 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CDJ45016.1 - 3e-53 180.7 0.0 5.4e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 CDJ45016.1 - 1.2e-47 161.5 0.0 4.9e-46 156.2 0.0 2.6 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CDJ45016.1 - 5.8e-14 51.4 0.1 1.1e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus RAWUL PF16207.5 CDJ45016.1 - 0.36 11.5 1.6 1.1 10.0 1.6 1.8 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like LRR_6 PF13516.6 CDJ45017.1 - 0.00078 19.3 3.7 0.013 15.5 0.5 3.2 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.7 CDJ45017.1 - 0.004 17.5 0.6 0.98 9.9 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) DUF992 PF06186.11 CDJ45017.1 - 0.043 13.6 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF992) DivIC PF04977.15 CDJ45018.1 - 3.9 7.3 7.2 3.9 7.3 1.6 2.8 2 0 0 2 2 2 0 Septum formation initiator LMBR1 PF04791.16 CDJ45019.1 - 0.0079 15.2 0.1 1 8.2 2.2 2.2 1 1 1 2 2 2 1 LMBR1-like membrane protein HxlR PF01638.17 CDJ45019.1 - 0.03 14.2 1.3 0.062 13.2 0.1 2.1 2 0 0 2 2 2 0 HxlR-like helix-turn-helix DUF2388 PF09498.10 CDJ45019.1 - 0.42 10.6 8.7 1 9.3 4.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) FlaC_arch PF05377.11 CDJ45019.1 - 0.46 10.9 5.9 0.17 12.3 1.1 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) SUIM_assoc PF16619.5 CDJ45020.1 - 0.0017 18.4 3.9 4.1 7.6 5.8 2.5 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Microtub_bind PF13931.6 CDJ45020.1 - 0.41 11.0 4.7 0.86 10.0 4.7 1.5 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding Presenilin PF01080.17 CDJ45020.1 - 1.4 7.6 4.4 2.1 7.0 4.4 1.3 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CDJ45020.1 - 2.6 8.7 12.9 0.035 14.8 4.2 2.3 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LMF1 PF06762.14 CDJ45023.1 - 1.4e-53 182.6 4.6 2.3e-53 181.9 4.6 1.2 1 0 0 1 1 1 1 Lipase maturation factor TAP35_44 PF07265.11 CDJ45023.1 - 0.12 12.4 0.0 5.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 XPG_I PF00867.18 CDJ45024.1 - 2.3e-20 72.8 0.1 7.8e-20 71.0 0.1 2.0 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 CDJ45024.1 - 0.0039 16.7 0.0 0.013 15.0 0.0 1.9 1 0 0 1 1 1 1 XPG domain containing EFF-AFF PF14884.6 CDJ45024.1 - 0.046 11.8 0.0 0.065 11.4 0.0 1.2 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen TSP_1 PF00090.19 CDJ45025.1 - 2e-101 332.1 238.1 9.3e-12 45.0 4.4 20.6 19 1 0 19 19 19 16 Thrombospondin type 1 domain Notch PF00066.17 CDJ45025.1 - 7.7e-25 87.1 92.0 2e-07 31.3 14.0 8.7 6 0 0 6 6 6 4 LNR domain CAP-ZIP_m PF15255.6 CDJ45025.1 - 0.11 12.8 0.1 29 4.9 0.0 2.9 2 0 0 2 2 2 0 WASH complex subunit CAP-Z interacting, central region RIBIOP_C PF04950.12 CDJ45026.1 - 1.2e-83 280.9 0.0 1.5e-82 277.3 0.0 2.2 1 1 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CDJ45026.1 - 5.1e-08 32.9 0.0 1.5e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain UPF0184 PF03670.13 CDJ45026.1 - 2 8.9 6.1 3.7 8.0 6.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) CCDC66 PF15236.6 CDJ45027.1 - 0.13 12.1 29.4 0.051 13.4 19.3 3.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 Tae4 PF14113.6 CDJ45029.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase effector protein 4 GST_C_6 PF17171.4 CDJ45030.1 - 6.7e-12 45.0 0.1 1.3e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 CDJ45030.1 - 7.4e-06 26.3 0.0 1.4e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 CDJ45030.1 - 0.011 15.7 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EGF_CA PF07645.15 CDJ45031.1 - 4.1e-16 58.9 23.0 1.9e-08 34.4 7.1 4.1 3 0 0 3 3 3 3 Calcium-binding EGF domain cEGF PF12662.7 CDJ45031.1 - 9.7e-11 41.4 21.2 2.2e-06 27.5 5.6 4.2 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CDJ45031.1 - 4.8e-09 36.3 24.5 0.0012 19.0 7.6 4.3 3 0 0 3 3 3 3 EGF domain Peptidase_C11 PF03415.14 CDJ45031.1 - 1.1e-06 28.3 0.0 6.5e-05 22.5 0.0 3.1 2 1 0 2 2 2 1 Clostripain family Notch PF00066.17 CDJ45031.1 - 5.2e-06 26.8 2.0 5.2e-06 26.8 2.0 2.6 3 0 0 3 3 3 1 LNR domain FXa_inhibition PF14670.6 CDJ45031.1 - 4.2e-05 23.7 18.6 0.0031 17.8 7.9 4.0 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF PF00008.27 CDJ45031.1 - 0.0052 17.1 2.7 0.0052 17.1 2.7 4.8 5 0 0 5 5 5 2 EGF-like domain EGF_MSP1_1 PF12946.7 CDJ45031.1 - 0.027 14.5 11.0 0.4 10.8 1.8 3.7 3 0 0 3 3 3 0 MSP1 EGF domain 1 RNase_Zc3h12a PF11977.8 CDJ45032.1 - 2.6e-05 24.1 0.0 0.00044 20.1 0.0 2.2 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain WWE PF02825.20 CDJ45032.1 - 0.17 12.5 0.5 0.4 11.3 0.2 1.8 2 0 0 2 2 2 0 WWE domain Nop14 PF04147.12 CDJ45033.1 - 0.00075 17.9 12.0 0.001 17.4 12.0 1.1 1 0 0 1 1 1 1 Nop14-like family RskA PF10099.9 CDJ45033.1 - 0.0089 16.3 4.2 0.16 12.3 0.1 2.9 3 0 0 3 3 3 1 Anti-sigma-K factor rskA Myc_N PF01056.18 CDJ45033.1 - 0.015 15.2 5.0 0.023 14.6 5.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DNA_pol_phi PF04931.13 CDJ45033.1 - 0.021 12.9 18.9 0.03 12.4 18.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Herpes_gE PF02480.16 CDJ45033.1 - 0.029 13.1 0.3 0.043 12.6 0.3 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MAP17 PF15807.5 CDJ45033.1 - 0.043 14.1 0.9 0.085 13.1 0.9 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RPN2_C PF18004.1 CDJ45033.1 - 0.087 12.7 4.0 0.17 11.8 4.0 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain V_ATPase_I PF01496.19 CDJ45033.1 - 0.11 10.4 0.3 0.15 9.9 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_pol_3_Rpc31 PF11705.8 CDJ45033.1 - 0.11 12.7 14.1 0.19 12.0 14.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SpoIIIAH PF12685.7 CDJ45033.1 - 0.27 11.0 5.8 0.52 10.1 5.8 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein TRAP_alpha PF03896.16 CDJ45033.1 - 0.47 9.6 7.5 0.78 8.9 7.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.12 CDJ45033.1 - 0.5 9.7 14.1 0.79 9.1 14.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 CDJ45033.1 - 0.62 9.4 18.6 1.3 8.4 18.6 1.5 1 0 0 1 1 1 0 SDA1 NPR3 PF03666.13 CDJ45033.1 - 0.7 8.6 4.8 0.97 8.1 4.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Vfa1 PF08432.10 CDJ45033.1 - 0.83 10.0 6.6 1.5 9.1 6.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PPP4R2 PF09184.11 CDJ45033.1 - 1.1 8.8 13.9 1.7 8.1 13.9 1.2 1 0 0 1 1 1 0 PPP4R2 Astro_capsid_p PF12226.8 CDJ45033.1 - 5.1 6.2 13.8 7.5 5.6 13.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein COPI_C PF06957.11 CDJ45033.1 - 6.8 5.3 11.8 14 4.3 11.8 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus CDC45 PF02724.14 CDJ45033.1 - 7.1 4.8 14.4 10 4.3 14.4 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 CDJ45033.1 - 8.6 5.6 16.7 16 4.7 16.7 1.3 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.16 CDJ45034.1 - 6.3e-19 68.1 36.1 1.4e-10 40.7 6.7 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily CcmD PF04995.14 CDJ45034.1 - 0.029 14.5 4.4 0.029 14.5 4.4 3.4 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Conotoxin PF02950.17 CDJ45034.1 - 0.15 13.1 1.9 1.1 10.3 0.0 3.0 3 0 0 3 3 3 0 Conotoxin DUF4752 PF15944.5 CDJ45034.1 - 0.2 11.7 0.6 0.5 10.5 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) YajC PF02699.15 CDJ45034.1 - 0.43 10.5 6.4 2.1 8.3 0.4 2.4 2 0 0 2 2 2 0 Preprotein translocase subunit TMEM72 PF16054.5 CDJ45034.1 - 3.4 7.3 5.8 4.8 6.8 2.2 2.3 2 0 0 2 2 2 0 Transmembrane protein family 72 DUF2681 PF10883.8 CDJ45034.1 - 4.9 7.6 10.1 10 6.6 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) MutS_V PF00488.21 CDJ45036.1 - 3e-08 33.9 0.2 0.0051 16.9 0.0 2.6 2 0 0 2 2 2 2 MutS domain V FAM220 PF15487.6 CDJ45036.1 - 0.2 11.3 10.4 0.58 9.8 10.4 1.7 1 0 0 1 1 1 0 FAM220 family Membralin PF09746.9 CDJ45036.1 - 6.8 5.6 9.3 13 4.7 9.3 1.3 1 0 0 1 1 1 0 Tumour-associated protein ALMT PF11744.8 CDJ45036.1 - 8 5.2 13.6 19 3.9 13.6 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter START PF01852.19 CDJ45037.1 - 4.1e-08 32.9 0.0 8.3e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 START domain AAA_23 PF13476.6 CDJ45037.1 - 0.00024 21.6 2.5 0.00037 21.0 2.5 1.2 1 0 0 1 1 1 1 AAA domain Suf PF05843.14 CDJ45037.1 - 0.0013 18.8 5.7 0.002 18.2 5.7 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DDHD PF02862.17 CDJ45037.1 - 0.0015 18.8 0.8 0.0019 18.4 0.8 1.3 1 0 0 1 1 1 1 DDHD domain Neur_chan_memb PF02932.16 CDJ45037.1 - 0.0047 17.0 3.7 0.0066 16.5 3.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ45037.1 - 0.005 16.7 9.8 0.0069 16.2 9.8 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 CDJ45037.1 - 0.014 14.2 10.1 0.02 13.7 10.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 CDJ45037.1 - 0.015 14.4 4.2 0.022 13.8 4.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4471 PF14740.6 CDJ45037.1 - 0.035 13.3 2.8 0.052 12.8 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) SpoIIP PF07454.11 CDJ45037.1 - 0.036 13.5 9.4 0.052 13.0 9.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 CDJ45037.1 - 0.044 13.8 24.7 0.065 13.2 24.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 CDJ45037.1 - 0.049 14.1 8.1 0.09 13.2 8.1 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4746 PF15928.5 CDJ45037.1 - 0.17 11.3 7.7 0.25 10.7 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Plasmodium_Vir PF05795.11 CDJ45037.1 - 0.19 11.1 2.0 0.25 10.7 2.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pex14_N PF04695.13 CDJ45037.1 - 0.2 12.3 19.9 0.49 11.1 19.9 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GREB1 PF15782.5 CDJ45037.1 - 0.32 8.1 4.6 0.36 7.9 4.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF913 PF06025.12 CDJ45037.1 - 0.37 9.7 5.2 0.53 9.2 5.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2058 PF09831.9 CDJ45037.1 - 0.85 9.8 19.6 21 5.2 18.8 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Presenilin PF01080.17 CDJ45037.1 - 1.1 7.9 14.7 1.6 7.4 14.7 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ45037.1 - 1.3 7.6 6.0 1.8 7.2 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF-3_zeta PF05091.12 CDJ45037.1 - 2 7.3 14.9 2.9 6.7 14.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Sec62 PF03839.16 CDJ45037.1 - 2.2 7.8 6.5 3.3 7.2 6.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PAT1 PF09770.9 CDJ45037.1 - 2.2 6.4 18.3 2.8 6.1 18.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Coilin_N PF15862.5 CDJ45037.1 - 3.6 7.4 14.8 0.5 10.2 10.5 1.7 2 0 0 2 2 1 0 Coilin N-terminus DUF4175 PF13779.6 CDJ45037.1 - 5.6 4.7 27.8 8.8 4.1 27.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDC45 PF02724.14 CDJ45037.1 - 6 5.0 12.2 10 4.2 12.2 1.3 1 0 0 1 1 1 0 CDC45-like protein SelP_N PF04592.14 CDJ45037.1 - 7.1 6.0 13.4 11 5.4 13.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region STAC2_u1 PF16664.5 CDJ45037.1 - 8.3 6.9 13.1 18 5.8 13.1 1.5 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 PLU-1 PF08429.11 CDJ45040.1 - 0.0016 17.7 3.8 0.0023 17.2 3.8 1.3 1 0 0 1 1 1 1 PLU-1-like protein Trp_oprn_chp PF09534.10 CDJ45042.1 - 0.0046 16.8 16.6 0.0046 16.8 16.6 2.4 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SR-25 PF10500.9 CDJ45042.1 - 0.0066 16.1 1.2 0.0066 16.1 1.2 2.9 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein RLL PF10036.9 CDJ45042.1 - 0.015 15.2 0.6 0.033 14.0 0.6 1.5 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Mid2 PF04478.12 CDJ45042.1 - 0.12 12.2 0.1 0.41 10.5 0.1 1.8 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Spt20 PF12090.8 CDJ45042.1 - 0.29 10.7 11.4 0.53 9.9 11.4 1.3 1 0 0 1 1 1 0 Spt20 family Peptidase_M17_N PF02789.17 CDJ45042.1 - 4.1 7.3 6.4 14 5.5 4.8 2.2 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain TFIIA PF03153.13 CDJ45043.1 - 2.2 8.2 13.3 3.2 7.6 13.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IMUP PF15761.5 CDJ45043.1 - 4.3 8.1 16.7 5.1 7.8 2.2 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein RskA PF10099.9 CDJ45044.1 - 0.0082 16.5 28.4 0.23 11.7 0.6 2.6 2 0 0 2 2 2 2 Anti-sigma-K factor rskA BRCA2 PF00634.18 CDJ45046.1 - 2.5e-14 52.6 0.0 0.024 14.3 0.0 4.7 4 0 0 4 4 4 4 BRCA2 repeat LPD38 PF18857.1 CDJ45046.1 - 0.034 14.3 1.2 7.4 6.7 0.0 3.3 2 2 2 4 4 4 0 Large polyvalent protein associated domain 38 BHD_3 PF10405.9 CDJ45046.1 - 1.4 9.4 2.7 19 5.7 0.0 3.3 4 0 0 4 4 4 0 Rad4 beta-hairpin domain 3 DUF3446 PF11928.8 CDJ45047.1 - 0.12 12.7 17.0 0.45 10.9 15.4 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain PI3_PI4_kinase PF00454.27 CDJ45048.1 - 3.8e-17 62.9 0.0 1.5e-15 57.7 0.0 2.6 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase SPX PF03105.19 CDJ45048.1 - 0.0042 17.1 0.0 0.0088 16.0 0.0 1.6 1 1 0 1 1 1 1 SPX domain Macoilin PF09726.9 CDJ45048.1 - 5.2 5.5 12.1 13 4.2 12.1 1.5 1 0 0 1 1 1 0 Macoilin family Ribosomal_L13 PF00572.18 CDJ45049.1 - 1.1e-10 41.8 0.1 6.8e-09 36.0 0.1 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 DUF3362 PF11842.8 CDJ45049.1 - 0.04 14.2 0.3 1.2 9.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3362) GPI2 PF06432.11 CDJ45051.1 - 2.4e-30 106.0 1.0 2.6e-30 105.8 1.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase CcmF_C PF16327.5 CDJ45051.1 - 0.0057 16.0 0.2 0.0064 15.8 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c-type biogenesis protein CcmF C-terminal HA2 PF04408.23 CDJ45053.1 - 7.4e-10 39.1 0.2 7.4e-10 39.1 0.2 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) Dehydrin PF00257.19 CDJ45054.1 - 0.038 14.5 1.2 0.038 14.5 1.2 4.2 3 1 1 4 4 4 0 Dehydrin Ribosomal_60s PF00428.19 CDJ45054.1 - 0.6 10.7 12.7 1.4 9.6 6.7 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ45055.1 - 4.6e-05 23.6 21.4 4.7e-05 23.6 21.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PIH1 PF08190.12 CDJ45055.1 - 0.00011 21.7 0.9 0.00011 21.7 0.9 2.6 1 1 1 2 2 1 1 PIH1 N-terminal domain Suf PF05843.14 CDJ45055.1 - 0.00018 21.6 8.9 0.00021 21.4 8.9 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) PIEZO PF15917.5 CDJ45055.1 - 0.0013 18.3 18.4 0.0019 17.7 18.4 1.3 1 0 0 1 1 1 1 Piezo CobT PF06213.12 CDJ45055.1 - 0.0025 17.2 14.3 0.0033 16.9 14.3 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Pex14_N PF04695.13 CDJ45055.1 - 0.0032 18.1 16.5 0.0051 17.5 16.5 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF913 PF06025.12 CDJ45055.1 - 0.0066 15.5 8.5 0.0092 15.0 8.5 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DUF572 PF04502.13 CDJ45055.1 - 0.014 15.0 11.8 0.016 14.9 11.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) TERB2 PF15101.6 CDJ45055.1 - 0.015 15.3 14.9 0.023 14.7 14.9 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAM60A PF15396.6 CDJ45055.1 - 0.019 15.0 12.1 0.026 14.5 12.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.17 CDJ45055.1 - 0.02 15.1 9.0 0.026 14.7 9.0 1.2 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 CDJ45055.1 - 0.026 14.6 5.2 0.023 14.8 5.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF5308 PF17233.2 CDJ45055.1 - 0.032 14.4 7.3 0.048 13.9 7.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) MRP-S27 PF10037.9 CDJ45055.1 - 0.035 13.0 13.8 0.036 13.0 13.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 CCDC53 PF10152.9 CDJ45055.1 - 0.043 14.2 11.7 0.068 13.6 11.7 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Borrelia_P83 PF05262.11 CDJ45055.1 - 0.045 12.2 13.0 0.055 12.0 13.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 CDJ45055.1 - 0.056 12.2 13.9 0.065 12.0 13.9 1.1 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.8 CDJ45055.1 - 0.082 11.8 20.3 0.025 13.5 17.2 1.6 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 CAC1F_C PF16885.5 CDJ45055.1 - 0.083 12.5 8.7 0.1 12.3 8.7 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term RP-C_C PF11800.8 CDJ45055.1 - 0.098 12.7 10.5 0.17 12.0 10.5 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region Peroxin-13_N PF04088.13 CDJ45055.1 - 0.11 12.7 9.0 0.19 12.0 9.0 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Radical_SAM_N PF08497.10 CDJ45055.1 - 0.12 11.6 3.1 0.11 11.7 3.1 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal DUF4834 PF16118.5 CDJ45055.1 - 0.12 13.3 14.0 0.35 11.9 14.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PIP5K PF01504.18 CDJ45055.1 - 0.18 11.0 8.7 0.24 10.6 8.7 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SID-1_RNA_chan PF13965.6 CDJ45055.1 - 0.19 10.1 2.4 0.17 10.3 2.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 V_ATPase_I PF01496.19 CDJ45055.1 - 0.2 9.5 12.0 0.24 9.3 12.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EIIBC-GUT_N PF03612.14 CDJ45055.1 - 0.2 11.3 12.7 0.33 10.7 12.7 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CAF1 PF04857.20 CDJ45055.1 - 0.24 10.5 7.7 0.33 10.1 7.7 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease LMBR1 PF04791.16 CDJ45055.1 - 0.26 10.2 10.1 0.3 9.9 10.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein CPSF100_C PF13299.6 CDJ45055.1 - 0.26 11.5 12.3 0.4 10.8 12.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2370 PF10176.9 CDJ45055.1 - 0.29 10.7 7.9 0.44 10.2 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Band_3_cyto PF07565.13 CDJ45055.1 - 0.31 10.8 12.8 0.48 10.2 12.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Glyco_transf_41 PF13844.6 CDJ45055.1 - 0.38 9.1 7.5 0.48 8.8 7.5 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 DUF2828 PF11443.8 CDJ45055.1 - 0.4 8.7 13.2 0.49 8.4 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF1754 PF08555.10 CDJ45055.1 - 0.42 11.5 22.9 0.77 10.6 22.9 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) ALMT PF11744.8 CDJ45055.1 - 0.42 9.4 11.2 0.58 8.9 11.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SpoIIP PF07454.11 CDJ45055.1 - 0.45 9.9 16.9 0.62 9.5 16.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) MMR1 PF08505.10 CDJ45055.1 - 0.45 10.8 18.7 0.73 10.1 18.7 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Hid1 PF12722.7 CDJ45055.1 - 0.49 8.5 11.2 0.59 8.2 11.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MCD PF05292.11 CDJ45055.1 - 0.55 9.7 8.1 1 8.9 8.0 1.5 2 0 0 2 2 1 0 Malonyl-CoA decarboxylase C-terminal domain TFB6 PF17110.5 CDJ45055.1 - 0.61 9.8 7.3 1 9.1 7.3 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4175 PF13779.6 CDJ45055.1 - 0.63 7.9 29.5 1 7.2 29.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EOS1 PF12326.8 CDJ45055.1 - 0.69 9.8 6.4 0.89 9.5 6.4 1.2 1 0 0 1 1 1 0 N-glycosylation protein AIF_C PF14721.6 CDJ45055.1 - 0.76 10.1 13.4 1.3 9.3 13.4 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ndc1_Nup PF09531.10 CDJ45055.1 - 0.81 8.3 10.3 1 8.0 10.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNA_pol_Rbc25 PF08292.12 CDJ45055.1 - 0.99 9.6 10.6 2 8.7 10.6 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Baculo_PP31 PF05311.11 CDJ45055.1 - 1.1 8.7 16.4 1.6 8.1 16.4 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Gti1_Pac2 PF09729.9 CDJ45055.1 - 1.3 9.1 12.2 2.1 8.4 12.2 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family eIF-3_zeta PF05091.12 CDJ45055.1 - 1.4 7.8 20.7 1.8 7.4 20.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 CDJ45055.1 - 1.4 7.8 15.4 0.68 8.9 13.2 1.5 2 0 0 2 2 2 0 Solute carrier family 12 DUF2722 PF10846.8 CDJ45055.1 - 1.5 7.6 32.1 2.6 6.9 32.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) VIR_N PF15912.5 CDJ45055.1 - 1.5 8.3 9.1 2.6 7.6 7.8 1.8 2 0 0 2 2 2 0 Virilizer, N-terminal Plasmodium_Vir PF05795.11 CDJ45055.1 - 1.5 8.1 9.5 2.4 7.5 9.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Folate_carrier PF01770.18 CDJ45055.1 - 1.7 7.3 6.8 2.1 7.0 6.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier Rtf2 PF04641.12 CDJ45055.1 - 1.8 7.9 17.9 2.6 7.3 17.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Hydin_ADK PF17213.3 CDJ45055.1 - 1.8 8.8 10.6 2.9 8.1 10.6 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain GNAT_acetyltr_2 PF13718.6 CDJ45055.1 - 1.9 7.9 12.2 3.5 6.9 12.2 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Serinc PF03348.15 CDJ45055.1 - 2.1 7.2 7.7 2.4 7.0 7.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Sec62 PF03839.16 CDJ45055.1 - 2.4 7.6 17.7 3.2 7.2 17.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Activator_LAG-3 PF11498.8 CDJ45055.1 - 2.5 7.0 41.1 3.1 6.6 41.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SPG4 PF17325.2 CDJ45055.1 - 2.7 9.1 22.5 17 6.5 0.2 3.3 2 1 1 3 3 3 0 Stationary phase protein 4 NPR3 PF03666.13 CDJ45055.1 - 2.9 6.6 15.3 4 6.1 15.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 CDJ45055.1 - 3.1 6.9 8.4 4 6.6 8.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CTU2 PF10288.9 CDJ45055.1 - 3.2 8.0 14.0 6.9 7.0 14.0 1.6 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 RBM39linker PF15519.6 CDJ45055.1 - 3.5 8.8 14.4 7 7.8 14.4 1.5 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein FAM176 PF14851.6 CDJ45055.1 - 3.9 7.1 10.5 7.3 6.2 10.5 1.4 1 0 0 1 1 1 0 FAM176 family DUF1764 PF08576.10 CDJ45055.1 - 4.6 8.2 16.6 10 7.1 16.6 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF2367 PF10164.9 CDJ45055.1 - 5.5 7.5 8.5 10 6.7 8.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Orf78 PF06024.12 CDJ45055.1 - 7 7.0 9.0 13 6.1 9.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Tim54 PF11711.8 CDJ45055.1 - 7 5.3 16.6 9.7 4.9 16.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDRGK PF09756.9 CDJ45055.1 - 8.8 5.9 29.2 18 4.9 29.2 1.4 1 0 0 1 1 1 0 DDRGK domain MDM31_MDM32 PF08118.11 CDJ45055.1 - 8.8 4.9 13.5 13 4.3 13.5 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Otopetrin PF03189.13 CDJ45055.1 - 9.3 4.9 8.7 12 4.6 8.7 1.1 1 0 0 1 1 1 0 Otopetrin Het-C PF07217.11 CDJ45055.1 - 9.8 4.6 12.7 14 4.0 12.7 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C RCC1_2 PF13540.6 CDJ45056.1 - 0.0055 16.5 11.5 0.05 13.4 0.2 4.6 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CDJ45056.1 - 5.7 7.7 6.8 6.2 7.5 0.3 3.4 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat DUF2232 PF09991.9 CDJ45057.1 - 2.6 7.2 3.8 2.1 7.5 0.2 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Tub_N PF16322.5 CDJ45058.1 - 0.17 12.3 35.1 0.2 12.0 35.1 1.1 1 0 0 1 1 1 0 Tubby N-terminal Macoilin PF09726.9 CDJ45058.1 - 0.23 10.0 33.1 0.26 9.8 33.1 1.1 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CDJ45058.1 - 1.8 8.5 40.4 2 8.3 40.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLC12 PF03522.15 CDJ45058.1 - 2.2 7.2 23.4 2.8 6.9 23.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 CDJ45058.1 - 2.4 7.7 29.8 2.8 7.4 29.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ45058.1 - 3.7 6.3 25.9 5 5.9 25.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Draxin PF15550.6 CDJ45058.1 - 7.5 6.3 25.2 10 5.9 25.2 1.3 1 0 0 1 1 1 0 Draxin DXP_reductoisom PF02670.16 CDJ45059.1 - 8.4e-34 117.1 0.0 8.4e-34 117.1 0.0 2.6 3 0 0 3 3 3 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase GFO_IDH_MocA PF01408.22 CDJ45059.1 - 0.22 12.4 5.5 0.47 11.3 0.0 3.3 2 1 1 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold Cpn60_TCP1 PF00118.24 CDJ45063.1 - 2.3e-129 432.2 0.0 3.4e-129 431.7 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_tranf_2_3 PF13641.6 CDJ45063.1 - 0.15 11.9 0.7 0.41 10.5 0.7 1.7 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Abhydrolase_1 PF00561.20 CDJ45064.1 - 4.9e-07 29.7 0.0 0.01 15.5 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ45064.1 - 2.1e-06 27.2 0.0 0.012 14.9 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DUF818 PF05677.12 CDJ45064.1 - 6.6e-05 22.0 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 CDJ45064.1 - 0.005 16.3 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CDJ45064.1 - 0.017 14.9 0.0 0.041 13.7 0.0 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Androgen_recep PF02166.16 CDJ45064.1 - 0.12 11.2 5.3 0.21 10.4 5.3 1.4 1 0 0 1 1 1 0 Androgen receptor Robl_LC7 PF03259.17 CDJ45065.1 - 4.2e-23 80.9 0.1 5.2e-23 80.6 0.1 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CDJ45065.1 - 0.00099 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 CDJ45065.1 - 0.056 13.8 0.0 0.074 13.4 0.0 1.3 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain CDC27 PF09507.10 CDJ45066.1 - 0.068 12.6 35.6 0.091 12.1 35.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Macoilin PF09726.9 CDJ45066.1 - 2.1 6.8 25.5 2.6 6.5 25.5 1.1 1 0 0 1 1 1 0 Macoilin family RR_TM4-6 PF06459.12 CDJ45066.1 - 4.4 7.1 31.9 6.5 6.5 31.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 CDJ45066.1 - 9.1 6.2 32.2 11 5.9 32.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 CDJ45066.1 - 9.1 3.2 23.8 11 3.0 23.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PepSY_2 PF13670.6 CDJ45066.1 - 9.7 6.3 14.1 4 7.5 1.9 2.6 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain SR-25 PF10500.9 CDJ45067.1 - 0.013 15.2 16.4 0.67 9.5 13.6 2.4 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Phage_TAC_7 PF10109.9 CDJ45067.1 - 0.081 13.1 3.2 0.8 9.9 0.0 3.4 2 1 1 3 3 3 0 Phage tail assembly chaperone proteins, E, or 41 or 14 BatA PF07584.11 CDJ45069.1 - 4.7 7.6 10.0 1.1 9.7 1.6 2.3 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal DUF3365 PF11845.8 CDJ45071.1 - 0.96 9.8 4.8 1.1 9.5 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) BRCT_2 PF16589.5 CDJ45073.1 - 5.4e-07 29.9 0.0 1.6e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CDJ45073.1 - 0.68 9.9 10.7 9.3 6.2 0.0 4.3 4 0 0 4 4 4 0 Regulator of Ty1 transposition protein 107 BRCT domain NIF PF03031.18 CDJ45074.1 - 6e-09 35.9 0.9 0.00039 20.2 0.1 3.1 2 1 1 3 3 3 2 NLI interacting factor-like phosphatase zf-C4H2 PF10146.9 CDJ45075.1 - 0.013 15.8 0.3 0.017 15.5 0.3 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein ABC1 PF03109.16 CDJ45077.1 - 4.4e-17 62.3 0.0 7.1e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 CDJ45077.1 - 0.036 14.0 0.2 0.036 14.0 0.2 2.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 CDJ45077.1 - 0.058 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain SR-25 PF10500.9 CDJ45077.1 - 3 7.4 63.0 0.14 11.8 7.2 5.2 5 0 0 5 5 5 0 Nuclear RNA-splicing-associated protein PHO4 PF01384.20 CDJ45078.1 - 3.1e-52 177.7 3.9 3.4e-52 177.6 3.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family TraG_N PF07916.11 CDJ45080.1 - 0.35 9.7 11.0 0.42 9.4 11.0 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region wnt PF00110.19 CDJ45080.1 - 0.5 9.9 8.1 0.58 9.7 8.1 1.2 1 0 0 1 1 1 0 wnt family Fusion_gly PF00523.18 CDJ45080.1 - 2.3 6.4 13.5 2.5 6.2 13.5 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 Virul_Fac PF10139.9 CDJ45080.1 - 3 6.0 9.9 3.5 5.7 9.9 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor RIFIN PF02009.16 CDJ45080.1 - 4 7.2 10.7 4.9 7.0 10.7 1.1 1 0 0 1 1 1 0 Rifin FAM104 PF15434.6 CDJ45081.1 - 0.3 11.7 11.2 1.3 9.6 3.4 3.8 3 0 0 3 3 3 0 Family 104 SR-25 PF10500.9 CDJ45082.1 - 1.1e-06 28.5 19.3 2.8e-06 27.1 8.1 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ45082.1 - 0.00091 19.5 20.3 0.012 15.9 8.0 2.7 2 0 0 2 2 2 2 Early growth response N-terminal domain DUF2722 PF10846.8 CDJ45082.1 - 0.0014 17.6 7.1 0.0014 17.6 7.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) AF-4 PF05110.13 CDJ45082.1 - 0.6 8.1 21.8 0.026 12.7 13.1 2.3 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Zip PF02535.22 CDJ45082.1 - 0.63 9.2 2.5 0.5 9.5 0.6 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Presenilin PF01080.17 CDJ45082.1 - 1.2 7.8 10.6 0.23 10.2 5.2 2.0 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 CDJ45082.1 - 1.4 8.9 6.4 2.6 8.0 3.4 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pex14_N PF04695.13 CDJ45082.1 - 3.1 8.4 23.4 0.44 11.2 8.7 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDHD PF02862.17 CDJ45082.1 - 6.5 6.8 14.8 52 3.9 12.9 2.3 2 1 0 2 2 2 0 DDHD domain NPR3 PF03666.13 CDJ45083.1 - 1 8.0 6.3 1.6 7.4 6.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 CDJ45083.1 - 2.6 8.1 9.1 3.6 7.7 6.7 2.0 2 0 0 2 2 2 0 DDHD domain DNA_pol_E_B PF04042.16 CDJ45084.1 - 0.00011 21.6 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Gp_dh_C PF02800.20 CDJ45084.1 - 0.015 14.9 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Med3 PF11593.8 CDJ45085.1 - 1.6e-05 24.3 22.7 2e-05 24.0 22.7 1.0 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal p450 PF00067.22 CDJ45085.1 - 0.082 11.6 0.1 0.099 11.4 0.1 1.1 1 0 0 1 1 1 0 Cytochrome P450 Nsp1_C PF05064.13 CDJ45085.1 - 1.5 8.6 8.2 52 3.7 8.2 2.2 1 1 0 1 1 1 0 Nsp1-like C-terminal region DUF4763 PF15960.5 CDJ45085.1 - 5.5 6.2 14.9 6.7 5.9 14.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Virul_Fac PF10139.9 CDJ45085.1 - 8 4.5 16.4 9.7 4.3 16.4 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor DUF3464 PF11947.8 CDJ45086.1 - 0.0016 18.2 1.0 0.0018 18.1 0.1 1.5 2 0 0 2 2 1 1 Photosynthesis affected mutant 68 Presenilin PF01080.17 CDJ45086.1 - 0.0047 15.8 0.8 0.0047 15.7 0.8 1.1 1 0 0 1 1 1 1 Presenilin DUF4386 PF14329.6 CDJ45086.1 - 0.0054 16.6 0.1 0.0054 16.6 0.1 2.1 2 0 0 2 2 1 1 Domain of unknown function (DUF4386) SpoIIP PF07454.11 CDJ45086.1 - 0.011 15.2 1.2 0.013 15.0 1.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4770 PF15994.5 CDJ45086.1 - 0.012 15.9 3.0 0.021 15.1 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF2722 PF10846.8 CDJ45086.1 - 0.012 14.6 13.7 0.016 14.2 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Tim54 PF11711.8 CDJ45086.1 - 0.012 14.4 0.2 0.014 14.2 0.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Activator_LAG-3 PF11498.8 CDJ45086.1 - 0.015 14.3 22.0 0.021 13.8 22.0 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DDHD PF02862.17 CDJ45086.1 - 0.019 15.1 0.4 0.019 15.1 0.4 1.2 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 CDJ45086.1 - 0.043 12.8 4.6 0.053 12.5 4.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Uroplakin_II PF07353.12 CDJ45086.1 - 0.049 13.1 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Uroplakin II Spt20 PF12090.8 CDJ45086.1 - 0.054 13.1 25.8 0.095 12.3 25.8 1.3 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ45086.1 - 0.08 13.9 6.3 0.14 13.1 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) OATP PF03137.20 CDJ45086.1 - 0.11 10.8 0.7 0.16 10.3 0.7 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MMR1 PF08505.10 CDJ45086.1 - 0.12 12.7 7.1 0.21 11.9 7.1 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Connexin PF00029.19 CDJ45086.1 - 0.17 11.7 0.6 0.23 11.2 0.6 1.2 1 0 0 1 1 1 0 Connexin DUF1980 PF09323.10 CDJ45086.1 - 0.28 11.1 2.4 0.4 10.6 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) EIIBC-GUT_N PF03612.14 CDJ45086.1 - 0.44 10.3 4.2 0.65 9.7 4.2 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CLN3 PF02487.17 CDJ45086.1 - 0.44 9.5 1.7 0.61 9.1 1.7 1.2 1 0 0 1 1 1 0 CLN3 protein Peptidase_S15 PF02129.18 CDJ45086.1 - 0.5 9.9 8.7 0.81 9.2 8.7 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) RskA PF10099.9 CDJ45086.1 - 0.76 10.0 32.2 3.1 8.1 32.2 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA RED_N PF07808.13 CDJ45086.1 - 0.88 9.1 14.3 2.2 7.8 14.3 1.6 1 1 0 1 1 1 0 RED-like protein N-terminal region TFIIA PF03153.13 CDJ45086.1 - 1.1 9.2 27.7 1.6 8.6 27.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 CDJ45086.1 - 1.4 8.6 4.3 2.6 7.7 4.3 1.3 1 0 0 1 1 1 0 FAM176 family V_ATPase_I PF01496.19 CDJ45086.1 - 2.3 6.0 6.4 3 5.7 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family R_equi_Vir PF05526.11 CDJ45086.1 - 2.9 7.7 5.9 5.3 6.9 5.9 1.4 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein UPF0565 PF10561.9 CDJ45086.1 - 3.3 6.8 7.7 0.26 10.4 2.6 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 UPF0560 PF10577.9 CDJ45086.1 - 3.8 5.9 13.5 5.4 5.4 13.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CNDH2_M PF16869.5 CDJ45086.1 - 5.7 7.6 9.8 0.69 10.6 4.4 2.0 2 0 0 2 2 2 0 PF16858 SANT_DAMP1_like PF16282.5 CDJ45087.1 - 5.9e-20 71.3 1.2 1.2e-19 70.2 1.2 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Activator_LAG-3 PF11498.8 CDJ45087.1 - 0.01 14.9 12.3 0.013 14.5 12.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HTH_Tnp_IS630 PF01710.16 CDJ45087.1 - 0.036 14.1 2.5 0.1 12.6 0.1 2.1 2 0 0 2 2 2 0 Transposase DUF5497 PF17601.2 CDJ45087.1 - 0.052 13.9 1.5 0.089 13.1 0.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5497) MLANA PF14991.6 CDJ45087.1 - 0.1 12.9 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein melan-A DUF2722 PF10846.8 CDJ45087.1 - 0.4 9.6 7.0 0.16 10.9 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Ins_P5_2-kin PF06090.12 CDJ45088.1 - 3.7e-21 75.9 11.9 1.3e-15 57.7 0.1 2.7 2 1 0 3 3 3 2 Inositol-pentakisphosphate 2-kinase Vps39_1 PF10366.9 CDJ45088.1 - 0.1 12.9 8.2 0.18 12.1 0.4 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 MAGE PF01454.19 CDJ45088.1 - 0.19 11.4 6.4 0.083 12.6 0.6 2.5 2 0 0 2 2 2 0 MAGE family OST-HTH PF12872.7 CDJ45089.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain DcuC PF03606.15 CDJ45089.1 - 0.019 13.4 0.6 0.019 13.4 0.6 2.2 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier DUF3653 PF12375.8 CDJ45089.1 - 0.11 12.6 0.2 0.11 12.6 0.2 2.0 2 0 0 2 2 2 0 Phage protein YdjM PF04307.14 CDJ45089.1 - 0.13 11.6 0.6 0.19 11.0 0.6 1.2 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Pinin_SDK_memA PF04696.13 CDJ45089.1 - 4.9 7.2 47.7 5.7 7.0 6.8 3.2 3 0 0 3 3 3 0 pinin/SDK/memA/ protein conserved region Connexin PF00029.19 CDJ45089.1 - 6.3 6.5 15.3 1.7 8.3 0.6 3.1 3 0 0 3 3 3 0 Connexin Peptidase_S8 PF00082.22 CDJ45091.1 - 1.3e-18 67.3 1.1 1.6e-18 67.0 1.1 1.1 1 0 0 1 1 1 1 Subtilase family DUF3883 PF13020.6 CDJ45092.1 - 3.1e-10 39.9 0.0 1.1e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HNOBA PF07701.14 CDJ45092.1 - 0.031 13.7 6.6 0.41 10.0 4.5 2.4 2 0 0 2 2 2 0 Heme NO binding associated SpoIIP PF07454.11 CDJ45092.1 - 1.1 8.6 20.2 0.21 11.0 9.7 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Pkinase_fungal PF17667.1 CDJ45092.1 - 2 7.1 12.8 3.7 6.2 4.4 2.3 2 0 0 2 2 2 0 Fungal protein kinase Gaa1 PF04114.14 CDJ45092.1 - 2.1 7.3 6.8 0.26 10.2 1.3 2.0 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component MMR1 PF08505.10 CDJ45092.1 - 2.2 8.5 45.1 0.082 13.2 9.0 3.1 2 1 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein PAT1 PF09770.9 CDJ45092.1 - 3.7 5.7 40.2 0.5 8.6 16.3 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 NST1 PF13945.6 CDJ45092.1 - 5 7.2 31.1 0.076 13.1 11.1 2.7 3 0 0 3 3 3 0 Salt tolerance down-regulator CDC45 PF02724.14 CDJ45092.1 - 6 5.0 18.4 0.055 11.8 4.9 2.2 2 0 0 2 2 2 0 CDC45-like protein vATP-synt_AC39 PF01992.16 CDJ45093.1 - 1.9e-81 274.2 0.1 2.3e-81 273.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit SUIM_assoc PF16619.5 CDJ45093.1 - 0.00056 19.9 0.6 0.0014 18.6 0.6 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 CSN8_PSD8_EIF3K PF10075.9 CDJ45093.1 - 0.07 13.1 0.8 0.62 10.0 0.1 2.3 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family SR-25 PF10500.9 CDJ45093.1 - 8.9 5.8 11.6 16 5.0 11.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GYF PF02213.16 CDJ45094.1 - 1.1e-08 34.6 0.1 1.8e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 GYF domain DUF724 PF05266.14 CDJ45096.1 - 0.049 13.5 1.2 0.08 12.8 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CRM1_C PF08767.11 CDJ45099.1 - 8.9e-77 258.4 6.5 1e-76 258.2 6.5 1.0 1 0 0 1 1 1 1 CRM1 C terminal GD_AH_C PF04295.13 CDJ45100.1 - 0.15 10.8 0.1 0.19 10.5 0.1 1.1 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus DUF5576 PF17739.1 CDJ45100.1 - 0.19 11.9 0.4 0.32 11.1 0.3 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5576) DUF3446 PF11928.8 CDJ45101.1 - 0.016 15.5 2.3 0.016 15.5 2.3 4.8 5 1 1 6 6 6 0 Early growth response N-terminal domain ERCC3_RAD25_C PF16203.5 CDJ45101.1 - 0.13 11.4 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Helicase_C PF00271.31 CDJ45101.1 - 0.17 12.2 0.0 0.76 10.1 0.0 2.0 2 0 0 2 2 2 0 Helicase conserved C-terminal domain SNF2_N PF00176.23 CDJ45102.1 - 2.6e-09 36.3 0.0 2.9e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain WD40 PF00400.32 CDJ45103.1 - 8.8e-08 32.7 2.8 0.00017 22.3 0.0 3.6 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ45103.1 - 5.7e-05 23.3 0.0 1.4 9.3 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RR_TM4-6 PF06459.12 CDJ45103.1 - 1.7 8.4 8.3 2.5 7.9 8.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SUIM_assoc PF16619.5 CDJ45103.1 - 2.2 8.4 22.8 1.9 8.6 15.1 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DAHP_synth_2 PF01474.16 CDJ45104.1 - 5.5e-46 157.0 0.0 5.6e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Class-II DAHP synthetase family zf-CCCH PF00642.24 CDJ45105.1 - 0.0023 17.8 24.2 0.068 13.1 0.2 4.4 4 1 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CDJ45105.1 - 0.019 15.2 0.7 0.059 13.6 0.7 1.8 1 0 0 1 1 1 0 Zinc-finger containing family zf_CCCH_4 PF18345.1 CDJ45105.1 - 0.031 14.4 0.5 0.031 14.4 0.5 5.3 5 0 0 5 5 5 0 Zinc finger domain zf-CCCH_2 PF14608.6 CDJ45105.1 - 0.064 13.8 8.2 3.5 8.2 0.6 3.7 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Baculo_p24 PF05073.12 CDJ45106.1 - 0.017 14.9 1.7 0.026 14.3 1.5 1.5 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Prominin PF05478.11 CDJ45106.1 - 0.03 12.3 0.2 0.036 12.0 0.2 1.1 1 0 0 1 1 1 0 Prominin FapA PF03961.13 CDJ45106.1 - 0.063 11.9 3.9 0.073 11.7 3.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A YgaB PF14182.6 CDJ45106.1 - 0.078 13.4 8.4 0.53 10.7 0.1 2.3 2 0 0 2 2 2 0 YgaB-like protein YtxH PF12732.7 CDJ45106.1 - 0.13 12.8 4.3 0.12 12.9 2.1 1.8 1 1 1 2 2 2 0 YtxH-like protein DUF3008 PF11450.8 CDJ45106.1 - 0.16 12.2 1.9 0.35 11.1 1.9 1.6 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) U1snRNP70_N PF12220.8 CDJ45106.1 - 0.17 12.6 4.1 0.22 12.2 4.1 1.2 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal EMP24_GP25L PF01105.24 CDJ45106.1 - 0.18 11.7 3.2 11 5.9 2.3 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Neur_chan_memb PF02932.16 CDJ45106.1 - 0.21 11.6 0.6 0.24 11.4 0.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FlxA PF14282.6 CDJ45106.1 - 0.25 11.4 9.4 0.12 12.4 2.8 2.1 2 0 0 2 2 2 0 FlxA-like protein G10 PF01125.17 CDJ45106.1 - 0.45 10.3 7.2 1.7 8.4 4.6 2.0 2 0 0 2 2 2 0 G10 protein CAF-1_p150 PF11600.8 CDJ45106.1 - 4.3 7.0 20.9 3.9 7.2 19.7 1.5 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Band_7 PF01145.25 CDJ45107.1 - 1.1e-21 77.6 0.2 2e-21 76.8 0.1 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family AAA_lid_4 PF17864.1 CDJ45107.1 - 0.061 13.1 0.9 0.16 11.7 0.0 2.1 2 1 0 2 2 2 0 RuvB AAA lid domain SR-25 PF10500.9 CDJ45108.1 - 0.00044 19.9 2.3 0.00044 19.9 2.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 CDJ45108.1 - 0.0026 18.3 2.5 0.0033 18.0 2.5 1.2 1 0 0 1 1 1 1 Dehydrin E3_UFM1_ligase PF09743.9 CDJ45109.1 - 6.8e-40 137.4 4.3 7.4e-30 104.5 0.0 2.7 1 1 2 3 3 3 2 E3 UFM1-protein ligase 1 DUF4820 PF16091.5 CDJ45109.1 - 0.07 12.5 0.5 0.11 11.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RNase_H2-Ydr279 PF09468.10 CDJ45110.1 - 0.049 13.8 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain RNase_H2-Ydr279 PF09468.10 CDJ45111.1 - 0.04 14.1 0.1 0.06 13.5 0.1 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain TBCC PF07986.12 CDJ45112.1 - 1.1e-13 50.9 0.1 1.1e-13 50.9 0.1 1.9 2 1 0 2 2 2 1 Tubulin binding cofactor C DUF4140 PF13600.6 CDJ45112.1 - 0.046 14.2 0.7 0.046 14.2 0.7 2.8 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Neur_chan_memb PF02932.16 CDJ45112.1 - 0.083 12.9 7.1 1.3 9.1 2.7 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4746 PF15928.5 CDJ45112.1 - 0.2 11.0 4.7 4.5 6.6 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Vfa1 PF08432.10 CDJ45112.1 - 0.26 11.6 13.3 1.2 9.4 0.6 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF1917 PF08939.10 CDJ45112.1 - 0.34 10.8 11.8 0.058 13.3 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) Presenilin PF01080.17 CDJ45112.1 - 1.2 7.8 10.4 2 7.1 0.6 2.2 2 0 0 2 2 2 0 Presenilin MCU PF04678.13 CDJ45112.1 - 1.3 9.1 12.6 4.5 7.3 4.1 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Exonuc_VII_L PF02601.15 CDJ45112.1 - 2.5 7.6 26.2 0.19 11.3 9.4 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit NLE PF08154.12 CDJ45113.1 - 2.1e-14 53.8 0.0 3.5e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 CDJ45113.1 - 2.8e-06 27.9 9.4 2.9 8.9 0.1 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ45113.1 - 0.00093 19.5 0.0 0.89 9.9 0.0 3.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ45113.1 - 0.17 10.5 0.0 8.7 4.9 0.0 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Helicase_C PF00271.31 CDJ45114.1 - 3.6e-27 94.9 0.1 5.7e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ45115.1 - 1.1e-20 74.1 0.0 1.4e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.6 CDJ45115.1 - 0.00033 20.1 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit RhlB PF12300.8 CDJ45115.1 - 0.19 11.9 10.6 0.26 11.4 10.6 1.1 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB CDK2AP PF09806.9 CDJ45115.1 - 7.4 6.6 9.6 10 6.1 9.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Pkinase PF00069.25 CDJ45116.1 - 8e-05 22.1 0.0 8e-05 22.1 0.0 2.8 3 1 0 3 3 3 1 Protein kinase domain PTPRCAP PF15713.5 CDJ45116.1 - 0.47 10.7 28.5 0.1 12.9 15.7 2.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CCSAP PF15748.5 CDJ45116.1 - 6.2 6.9 43.0 0.78 9.9 21.1 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated LRR_8 PF13855.6 CDJ45117.1 - 1.9e-08 33.9 39.1 9.7e-05 22.1 8.6 5.9 5 1 0 6 6 6 4 Leucine rich repeat Scs3p PF10261.9 CDJ45117.1 - 3.3 7.2 9.3 0.18 11.3 0.2 3.1 3 0 0 3 3 3 0 Inositol phospholipid synthesis and fat-storage-inducing TM EMP24_GP25L PF01105.24 CDJ45118.1 - 3.3e-17 63.0 0.9 3.6e-17 62.9 0.9 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Herpes_BLLF1 PF05109.13 CDJ45119.1 - 7.6 4.4 16.6 9.6 4.0 16.6 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TFIIA PF03153.13 CDJ45120.1 - 4.8 7.1 7.8 7.2 6.5 7.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pyr_redox_2 PF07992.14 CDJ45121.1 - 2.9e-28 98.9 0.0 1.8e-24 86.5 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ45121.1 - 2.6e-08 34.3 0.1 1.4e-06 28.8 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Activator_LAG-3 PF11498.8 CDJ45121.1 - 0.00044 19.3 40.3 0.00044 19.3 40.3 2.7 3 0 0 3 3 3 1 Transcriptional activator LAG-3 SLC12 PF03522.15 CDJ45121.1 - 0.0017 17.5 3.1 0.0025 16.9 3.1 1.2 1 0 0 1 1 1 1 Solute carrier family 12 DUF4746 PF15928.5 CDJ45121.1 - 0.002 17.6 2.1 0.0038 16.7 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) PAT1 PF09770.9 CDJ45121.1 - 0.018 13.3 14.2 0.035 12.4 14.2 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.19 CDJ45121.1 - 0.052 11.5 5.5 0.073 11.0 5.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCSAP PF15748.5 CDJ45121.1 - 0.056 13.6 12.7 0.016 15.4 9.5 1.7 2 0 0 2 2 1 0 Centriole, cilia and spindle-associated NAD_binding_7 PF13241.6 CDJ45121.1 - 0.11 13.0 1.0 1.5 9.3 0.0 3.1 2 1 0 2 2 2 0 Putative NAD(P)-binding TCP PF03634.13 CDJ45121.1 - 0.12 12.9 13.1 0.34 11.5 13.1 1.8 1 0 0 1 1 1 0 TCP family transcription factor SpoIIP PF07454.11 CDJ45121.1 - 0.15 11.5 7.7 0.29 10.5 7.7 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Neur_chan_memb PF02932.16 CDJ45121.1 - 0.17 12.0 2.3 0.3 11.1 2.3 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EcoRI_methylase PF13651.6 CDJ45121.1 - 0.17 11.1 1.4 0.24 10.6 1.4 1.1 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI Presenilin PF01080.17 CDJ45121.1 - 0.37 9.5 9.6 0.64 8.7 9.6 1.3 1 0 0 1 1 1 0 Presenilin Eapp_C PF10238.9 CDJ45121.1 - 0.51 10.4 7.6 1.5 8.9 7.6 1.8 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF572 PF04502.13 CDJ45121.1 - 0.61 9.6 8.6 0.15 11.7 5.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) ALMT PF11744.8 CDJ45121.1 - 0.62 8.8 5.6 1 8.1 5.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM60A PF15396.6 CDJ45121.1 - 1.3 9.0 8.6 3.8 7.4 8.6 1.8 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.12 CDJ45121.1 - 2.4 7.9 15.8 48 3.7 14.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 EPL1 PF10513.9 CDJ45121.1 - 4 7.8 11.9 10 6.5 11.8 1.7 1 1 0 1 1 1 0 Enhancer of polycomb-like Connexin PF00029.19 CDJ45121.1 - 4.1 7.1 5.8 11 5.7 5.8 1.6 1 0 0 1 1 1 0 Connexin MCU PF04678.13 CDJ45121.1 - 6.3 6.9 10.1 0.95 9.5 5.8 1.9 2 0 0 2 2 1 0 Mitochondrial calcium uniporter CLN3 PF02487.17 CDJ45121.1 - 8.8 5.2 5.9 16 4.4 5.9 1.3 1 0 0 1 1 1 0 CLN3 protein YABBY PF04690.13 CDJ45121.1 - 9.6 6.7 7.0 29 5.2 7.0 1.8 1 0 0 1 1 1 0 YABBY protein SelP_N PF04592.14 CDJ45122.1 - 0.64 9.4 18.6 0.076 12.4 13.7 1.7 1 1 1 2 2 2 0 Selenoprotein P, N terminal region DUF4179 PF13786.6 CDJ45122.1 - 0.84 10.2 5.6 15 6.1 5.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) DAP_epimerase PF01678.19 CDJ45122.1 - 2 8.6 4.3 1.8 8.8 2.4 1.8 1 1 0 1 1 1 0 Diaminopimelate epimerase SLATT_1 PF18181.1 CDJ45122.1 - 3.9 7.4 17.6 0.8 9.6 13.4 1.9 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF3740 PF12548.8 CDJ45122.1 - 8.4 6.8 14.8 11 6.5 1.3 2.2 2 0 0 2 2 2 0 Sulfatase protein Proteasome PF00227.26 CDJ45123.1 - 1.7e-55 187.5 0.5 2.4e-55 187.0 0.5 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ45123.1 - 2.1e-12 46.5 0.0 3.8e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF4194 PF13835.6 CDJ45123.1 - 0.098 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) Cas_Cas1 PF01867.16 CDJ45124.1 - 0.0057 15.8 0.5 0.0083 15.3 0.5 1.2 1 0 0 1 1 1 1 CRISPR associated protein Cas1 PLC-beta_C PF08703.10 CDJ45124.1 - 0.39 10.7 9.7 0.96 9.4 0.3 2.1 1 1 1 2 2 2 0 PLC-beta C terminal Cpn60_TCP1 PF00118.24 CDJ45125.1 - 0.0014 17.4 0.0 0.0016 17.1 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SET PF00856.28 CDJ45126.1 - 1.1e-14 55.2 0.0 2.4e-13 50.8 0.0 2.6 2 1 0 2 2 2 1 SET domain TP2 PF01254.18 CDJ45126.1 - 0.00082 20.0 4.8 0.0013 19.3 4.8 1.3 1 0 0 1 1 1 1 Nuclear transition protein 2 SR-25 PF10500.9 CDJ45126.1 - 0.0011 18.7 7.0 0.0018 17.9 7.0 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein GvpL_GvpF PF06386.11 CDJ45126.1 - 0.053 13.4 1.7 0.11 12.5 1.0 1.8 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF HEAT PF02985.22 CDJ45128.1 - 4.9e-14 51.2 15.1 0.00092 19.3 0.1 7.8 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 CDJ45128.1 - 1.1e-10 41.8 0.0 1.3e-07 31.9 0.0 6.1 3 2 3 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 CDJ45128.1 - 2.9e-10 40.4 1.5 1.6e-06 28.4 0.0 7.3 6 2 3 9 9 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CDJ45128.1 - 1.2e-08 35.4 0.9 0.0005 20.6 0.0 5.5 4 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CDJ45128.1 - 7.2e-07 29.4 0.0 0.00011 22.3 0.0 3.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 CDJ45128.1 - 2.1e-06 27.6 5.6 1.2 9.3 0.0 5.9 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 CDJ45128.1 - 0.00035 20.2 0.4 0.079 12.5 0.0 3.9 2 2 0 2 2 2 1 Tti2 family CLASP_N PF12348.8 CDJ45128.1 - 0.0014 18.3 0.4 0.02 14.4 0.0 3.0 3 1 1 4 4 4 1 CLASP N terminal DUF4704 PF15787.5 CDJ45128.1 - 0.032 13.5 4.4 2 7.6 1.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) SopA_C PF13979.6 CDJ45128.1 - 0.051 13.3 0.0 0.051 13.3 0.0 2.7 3 0 0 3 3 3 0 SopA-like catalytic domain Adaptin_N PF01602.20 CDJ45128.1 - 0.16 10.5 0.9 1.7 7.1 0.4 2.8 2 1 0 2 2 2 0 Adaptin N terminal region FANCI_S1 PF14675.6 CDJ45128.1 - 0.82 9.2 6.1 12 5.4 0.1 4.5 4 1 0 5 5 5 0 FANCI solenoid 1 DUF1840 PF08895.11 CDJ45128.1 - 5.2 7.4 7.2 16 5.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Spore_III_AB PF09548.10 CDJ45128.1 - 8.8 6.4 9.4 0.32 11.1 0.2 3.3 5 0 0 5 5 5 0 Stage III sporulation protein AB (spore_III_AB) XRN1_D2_D3 PF18334.1 CDJ45129.1 - 0.023 14.9 0.9 0.023 14.9 0.9 2.5 2 1 2 4 4 4 0 Exoribonuclease Xrn1 D2/D3 domain FAM70 PF14967.6 CDJ45129.1 - 0.15 11.5 3.7 0.23 10.9 3.7 1.3 1 0 0 1 1 1 0 FAM70 protein GRIM-19 PF06212.12 CDJ45129.1 - 0.48 10.4 6.8 1.3 9.0 2.6 2.3 1 1 1 2 2 2 0 GRIM-19 protein ALMT PF11744.8 CDJ45129.1 - 0.69 8.7 8.6 0.88 8.3 8.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CK_II_beta PF01214.18 CDJ45129.1 - 0.74 9.6 6.4 11 5.8 4.3 2.2 1 1 1 2 2 2 0 Casein kinase II regulatory subunit Calici_coat_C PF08435.11 CDJ45129.1 - 1.7 8.1 9.9 2.7 7.4 9.4 1.6 1 1 1 2 2 2 0 Calicivirus coat protein C-terminal ACPS PF01648.20 CDJ45130.1 - 1.1e-12 48.1 0.0 6.9e-10 39.1 0.0 2.8 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily UPF0054 PF02130.17 CDJ45130.1 - 5.8e-06 26.1 1.1 2.8e-05 23.9 1.1 1.9 1 1 0 1 1 1 1 Uncharacterized protein family UPF0054 MMR1 PF08505.10 CDJ45131.1 - 0.15 12.4 9.8 0.19 12.0 9.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FSA_C PF10479.9 CDJ45131.1 - 0.28 9.3 10.2 0.29 9.2 10.2 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus TFIIA PF03153.13 CDJ45131.1 - 0.88 9.5 16.7 1.1 9.1 16.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ45131.1 - 4.3 6.9 11.7 5.4 6.6 11.7 1.2 1 0 0 1 1 1 0 Spt20 family Hepcidin PF06446.12 CDJ45131.1 - 7.1 7.1 20.0 0.23 11.9 9.0 2.7 2 2 0 2 2 2 0 Hepcidin Sec1 PF00995.23 CDJ45132.1 - 3.4e-41 142.1 0.0 4.2e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family IMUP PF15761.5 CDJ45132.1 - 0.02 15.6 1.4 0.02 15.6 1.4 1.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein RCC1 PF00415.18 CDJ45133.1 - 1.3e-18 67.4 2.8 5.2e-07 30.2 0.1 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ45133.1 - 3.3e-05 23.5 2.5 0.0039 17.0 0.1 2.4 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat DEAD PF00270.29 CDJ45135.1 - 2.3e-42 144.7 1.0 7.6e-42 143.0 1.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ45135.1 - 7.6e-25 87.4 0.2 2e-22 79.6 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain GUCT PF08152.12 CDJ45135.1 - 3e-05 24.2 0.0 0.0058 16.9 0.0 3.2 1 1 0 1 1 1 1 GUCT (NUC152) domain Lipase_3 PF01764.25 CDJ45136.1 - 2.2e-12 47.0 0.4 6.2e-12 45.6 0.0 2.0 2 1 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 CDJ45136.1 - 0.0037 16.8 0.1 0.0037 16.8 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CDJ45136.1 - 0.03 14.9 0.2 0.061 13.9 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 CDJ45136.1 - 0.044 13.3 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ketoacyl-synt_2 PF13723.6 CDJ45136.1 - 0.064 12.9 8.4 0.17 11.5 8.4 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain IMUP PF15761.5 CDJ45136.1 - 0.37 11.5 6.3 0.81 10.4 6.3 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Baculo_PP31 PF05311.11 CDJ45136.1 - 3.1 7.2 8.2 3.1 7.2 4.4 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Pex14_N PF04695.13 CDJ45136.1 - 3.6 8.2 14.6 50 4.5 11.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ctr PF04145.15 CDJ45136.1 - 7.7 7.1 9.3 15 6.2 0.0 2.2 2 0 0 2 2 2 0 Ctr copper transporter family Spt20 PF12090.8 CDJ45137.1 - 0.0037 16.9 14.1 0.005 16.5 14.1 1.3 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ45137.1 - 0.01 15.9 28.2 0.011 15.7 28.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 CDJ45137.1 - 0.036 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain PAT1 PF09770.9 CDJ45137.1 - 0.046 12.0 11.1 0.046 12.0 11.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 iPGM_N PF06415.13 CDJ45137.1 - 0.098 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) SpoIIP PF07454.11 CDJ45137.1 - 0.35 10.3 3.1 0.4 10.1 3.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ45137.1 - 0.46 9.4 5.6 0.48 9.3 5.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lin-8 PF03353.15 CDJ45137.1 - 0.49 9.9 11.1 0.6 9.6 10.7 1.3 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ45137.1 - 0.66 9.5 21.4 1.4 8.5 8.6 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 CDJ45137.1 - 1.7 5.7 15.8 2 5.4 15.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF945 PF06097.11 CDJ45137.1 - 2.7 7.0 12.2 4.4 6.3 12.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Hid1 PF12722.7 CDJ45137.1 - 7.9 4.5 7.6 8.5 4.4 7.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4392 PF14336.6 CDJ45138.1 - 1.8e-05 24.3 0.5 0.038 13.4 0.3 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4392) SUIM_assoc PF16619.5 CDJ45138.1 - 0.0051 16.9 18.2 0.0069 16.4 3.9 2.4 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 COX14 PF14880.6 CDJ45138.1 - 0.14 12.0 0.2 0.14 12.0 0.2 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Dehydrin PF00257.19 CDJ45138.1 - 0.16 12.5 8.3 0.8 10.2 5.4 2.1 2 0 0 2 2 2 0 Dehydrin 7tm_7 PF08395.12 CDJ45138.1 - 0.45 9.7 2.2 0.76 8.9 0.0 1.9 2 0 0 2 2 2 0 7tm Chemosensory receptor Spt20 PF12090.8 CDJ45138.1 - 1.2 8.7 18.3 0.044 13.4 1.6 2.1 2 0 0 2 2 2 0 Spt20 family Helicase_C PF00271.31 CDJ45139.1 - 1.6e-16 60.6 2.6 3.9e-16 59.4 0.0 2.5 2 2 0 2 2 2 1 Helicase conserved C-terminal domain Paf67 PF10255.9 CDJ45139.1 - 0.072 12.1 2.0 0.11 11.5 2.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Abhydrolase_9_N PF15420.6 CDJ45140.1 - 0.19 11.7 1.6 0.21 11.6 1.6 1.0 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus FTA4 PF13093.6 CDJ45141.1 - 0.018 15.0 1.9 0.026 14.4 0.9 1.7 2 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Collagen PF01391.18 CDJ45142.1 - 0.0082 15.9 10.4 0.014 15.2 10.4 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) RPN2_C PF18004.1 CDJ45143.1 - 2.7e-10 40.4 10.3 8.6e-09 35.5 11.1 4.1 2 1 1 3 3 3 2 26S proteasome regulatory subunit RPN2 C-terminal domain Pep1_7 PF17232.2 CDJ45143.1 - 0.046 14.2 2.4 0.046 14.2 2.4 3.8 4 1 1 5 5 5 0 Elicitor peptide 1-7 Alk_phosphatase PF00245.20 CDJ45144.1 - 6.4 5.6 13.3 0.1 11.5 5.9 1.7 2 0 0 2 2 2 0 Alkaline phosphatase DUF755 PF05501.11 CDJ45145.1 - 0.00023 21.4 4.1 0.00023 21.4 4.1 9.0 6 1 3 9 9 9 1 Domain of unknown function (DUF755) DUF2076 PF09849.9 CDJ45145.1 - 0.0089 16.1 10.3 0.0089 16.1 10.3 5.7 5 1 1 6 6 6 2 Uncharacterized protein conserved in bacteria (DUF2076) AAA_5 PF07728.14 CDJ45145.1 - 0.018 15.0 0.2 0.18 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 CDJ45145.1 - 0.047 14.0 1.2 0.22 11.9 1.2 2.2 1 0 0 1 1 1 0 AAA C-terminal domain tRNA_lig_CPD PF08302.11 CDJ45145.1 - 3.3 7.1 7.7 2.2 7.7 1.9 2.5 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain RRM_1 PF00076.22 CDJ45146.1 - 8.8e-09 35.1 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TMEM223 PF14640.6 CDJ45146.1 - 0.015 15.5 0.4 0.027 14.7 0.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 223 CLN3 PF02487.17 CDJ45146.1 - 0.17 10.9 1.1 0.25 10.4 1.1 1.2 1 0 0 1 1 1 0 CLN3 protein Spt20 PF12090.8 CDJ45146.1 - 0.57 9.8 29.3 0.56 9.8 17.2 2.1 2 0 0 2 2 2 0 Spt20 family DUF3371 PF11851.8 CDJ45146.1 - 1.3 10.1 11.4 12 7.0 6.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) DUF3408 PF11888.8 CDJ45146.1 - 6.5 6.9 8.7 2.1 8.5 4.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF2722 PF10846.8 CDJ45146.1 - 7.6 5.4 21.9 12 4.7 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF1930 PF09122.10 CDJ45147.1 - 0.022 14.7 0.1 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) BUD22 PF09073.10 CDJ45147.1 - 0.042 13.2 27.0 0.046 13.1 27.0 1.1 1 0 0 1 1 1 0 BUD22 PNISR PF15996.5 CDJ45147.1 - 3.3 7.9 23.4 6.4 7.0 23.4 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Cwf_Cwc_15 PF04889.12 CDJ45147.1 - 5.2 6.7 19.6 7.3 6.2 19.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SPX PF03105.19 CDJ45147.1 - 5.7 6.7 21.5 6.9 6.5 21.5 1.2 1 0 0 1 1 1 0 SPX domain RRP36 PF06102.12 CDJ45148.1 - 1.7e-10 41.1 25.8 2e-10 40.9 25.8 1.1 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 DEK_C PF08766.11 CDJ45148.1 - 0.006 16.5 3.1 0.006 16.5 3.1 1.7 2 0 0 2 2 2 1 DEK C terminal domain Coat_F PF07875.12 CDJ45148.1 - 0.64 10.3 4.0 1.5 9.1 0.4 2.2 2 0 0 2 2 2 0 Coat F domain LST1 PF05083.13 CDJ45148.1 - 2.7 8.4 7.3 0.5 10.7 0.5 2.6 1 1 1 2 2 2 0 LST-1 protein DUF1707 PF08044.11 CDJ45148.1 - 5.2 7.2 8.3 21 5.3 4.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1707) SMC_N PF02463.19 CDJ45149.1 - 1.4e-23 83.5 1.3 3.4e-23 82.2 0.2 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDJ45149.1 - 8e-14 52.6 1.3 2.3e-12 47.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CDJ45149.1 - 3.1e-06 27.2 0.1 5.9e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDJ45149.1 - 3.5e-06 27.0 0.2 6.3e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CDJ45149.1 - 1e-05 25.2 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CDJ45149.1 - 0.017 15.7 0.3 0.017 15.7 0.3 2.8 2 2 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.17 CDJ45149.1 - 0.038 13.7 1.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 CDJ45149.1 - 0.074 13.1 2.3 0.11 12.5 0.1 2.4 2 1 1 3 3 3 0 Helicase HerA, central domain SR-25 PF10500.9 CDJ45149.1 - 3.4 7.2 25.5 0.72 9.4 10.8 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DDHD PF02862.17 CDJ45150.1 - 1.3e-09 38.5 7.4 5.5e-09 36.5 7.4 1.8 1 1 0 1 1 1 1 DDHD domain AF-4 PF05110.13 CDJ45150.1 - 0.32 9.0 11.2 0.36 8.9 11.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4179 PF13786.6 CDJ45151.1 - 0.71 10.4 0.0 0.71 10.4 0.0 4.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) Metallophos PF00149.28 CDJ45154.1 - 0.0033 18.0 0.0 0.0041 17.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Apt1 PF10351.9 CDJ45154.1 - 0.76 8.6 4.4 0.94 8.3 4.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ45154.1 - 4 7.3 13.0 5.8 6.7 13.0 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 CDJ45154.1 - 4.9 5.6 5.5 6.7 5.1 5.5 1.3 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 CDJ45154.1 - 5.7 5.5 6.9 6.4 5.3 6.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup S100PBPR PF15427.6 CDJ45154.1 - 5.8 6.1 8.2 8.3 5.6 8.2 1.1 1 0 0 1 1 1 0 S100P-binding protein SR-25 PF10500.9 CDJ45154.1 - 6.5 6.3 17.4 1.1 8.9 13.0 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.9 CDJ45157.1 - 0.0018 16.6 41.6 0.0021 16.4 41.6 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Rrn6 PF10214.9 CDJ45157.1 - 0.51 8.8 28.3 0.69 8.3 28.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CD20 PF04103.15 CDJ45157.1 - 0.65 10.1 0.0 0.65 10.1 0.0 3.1 2 1 0 2 2 2 0 CD20-like family Ribosomal_60s PF00428.19 CDJ45157.1 - 0.77 10.4 16.0 0.16 12.6 6.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein GREB1 PF15782.5 CDJ45157.1 - 1.4 5.9 22.1 1.7 5.7 22.1 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Asp-B-Hydro_N PF05279.11 CDJ45157.1 - 5.6 6.9 17.8 9.4 6.2 17.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4653 PF15546.6 CDJ45158.1 - 0.34 10.5 5.0 0.64 9.6 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF4653 PF15546.6 CDJ45159.1 - 0.34 10.5 5.0 0.64 9.6 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF4653 PF15546.6 CDJ45160.1 - 0.36 10.4 4.5 0.7 9.5 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Nucleo_P87 PF07267.11 CDJ45160.1 - 5.5 5.7 7.0 6.8 5.4 7.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4653 PF15546.6 CDJ45161.1 - 0.46 10.1 5.4 0.87 9.2 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF4653 PF15546.6 CDJ45162.1 - 0.43 10.2 4.5 0.79 9.3 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Longin PF13774.6 CDJ45164.1 - 7.3e-09 35.5 0.4 4e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Regulated-SNARE-like domain TFIIA PF03153.13 CDJ45164.1 - 0.00016 21.8 21.8 0.0002 21.5 21.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit TraG_N PF07916.11 CDJ45164.1 - 0.41 9.4 6.5 0.52 9.1 6.5 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region AAA_23 PF13476.6 CDJ45164.1 - 1.2 9.6 14.2 1.4 9.3 14.2 1.2 1 0 0 1 1 1 0 AAA domain Synaptobrevin PF00957.21 CDJ45164.1 - 7.4 6.4 10.4 6 6.7 8.0 2.0 1 1 1 2 2 2 0 Synaptobrevin PAT1 PF09770.9 CDJ45165.1 - 5.3 5.2 66.8 0.15 10.3 54.8 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.7 CDJ45167.1 - 0.0013 18.5 2.5 0.0018 18.1 2.5 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TMEM208_SND2 PF05620.11 CDJ45167.1 - 0.013 15.3 1.7 0.013 15.3 1.7 1.9 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Spt20 PF12090.8 CDJ45167.1 - 0.099 12.2 18.0 0.056 13.1 6.3 2.2 2 0 0 2 2 2 0 Spt20 family Med31 PF05669.12 CDJ45167.1 - 0.12 12.4 2.5 0.27 11.2 2.5 1.5 1 0 0 1 1 1 0 SOH1 Activator_LAG-3 PF11498.8 CDJ45167.1 - 1.2 8.1 28.4 1.7 7.5 4.5 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Pap_E4 PF02711.14 CDJ45167.1 - 1.7 9.7 8.0 0.69 10.9 1.7 2.2 2 0 0 2 2 2 0 E4 protein DUF2722 PF10846.8 CDJ45167.1 - 2.4 7.0 15.8 0.13 11.2 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TSP_1 PF00090.19 CDJ45170.1 - 2.4e-06 27.6 0.3 2.4e-06 27.6 0.3 4.2 3 0 0 3 3 3 1 Thrombospondin type 1 domain DUF870 PF05912.11 CDJ45170.1 - 0.023 14.7 1.3 0.063 13.3 1.3 1.8 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF870) AAA_23 PF13476.6 CDJ45170.1 - 8.2 6.9 32.7 2.8 8.4 1.3 3.3 3 0 0 3 3 3 0 AAA domain RskA PF10099.9 CDJ45172.1 - 0.00083 19.7 7.6 0.0013 19.1 7.6 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA 2OG-FeII_Oxy_2 PF13532.6 CDJ45172.1 - 0.012 15.9 5.2 0.2 11.8 5.2 2.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TFIIA PF03153.13 CDJ45172.1 - 1.2 9.1 38.3 2.1 8.2 38.3 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 CDJ45172.1 - 7.1 5.9 11.6 11 5.3 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3997 PF13162.6 CDJ45173.1 - 0.056 13.7 0.9 0.12 12.7 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) RNA_pol_Rpb2_1 PF04563.15 CDJ45173.1 - 0.19 11.2 0.3 0.27 10.7 0.3 1.2 1 0 0 1 1 1 0 RNA polymerase beta subunit Pribosyltran PF00156.27 CDJ45175.1 - 1.8e-11 43.8 0.2 1.8e-11 43.8 0.2 2.7 2 1 0 2 2 2 1 Phosphoribosyl transferase domain CCDC106 PF15794.5 CDJ45175.1 - 0.04 13.6 0.1 0.04 13.6 0.1 3.9 3 1 1 4 4 4 0 Coiled-coil domain-containing protein 106 DUF3138 PF11336.8 CDJ45176.1 - 0.05 12.2 1.8 0.065 11.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) YgaB PF14182.6 CDJ45176.1 - 0.07 13.5 0.3 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 YgaB-like protein Ribosomal_60s PF00428.19 CDJ45176.1 - 0.07 13.7 5.4 0.12 13.0 5.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Syd PF07348.12 CDJ45176.1 - 0.11 12.1 0.1 0.18 11.5 0.1 1.3 1 1 0 1 1 1 0 Syd protein (SUKH-2) SlyX PF04102.12 CDJ45176.1 - 0.35 11.5 1.8 0.67 10.6 0.2 2.2 2 1 0 2 2 2 0 SlyX DUF3138 PF11336.8 CDJ45179.1 - 0.085 11.5 1.9 0.1 11.2 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) HA2 PF04408.23 CDJ45183.1 - 5.4e-24 84.5 7.6 3.6e-23 81.9 0.1 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ45183.1 - 7.8e-22 77.4 0.0 1.5e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold TFIIA PF03153.13 CDJ45183.1 - 0.021 14.8 20.4 0.032 14.3 20.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 CDJ45183.1 - 4.2 6.4 24.6 7.2 5.7 24.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DNA_pol_phi PF04931.13 CDJ45184.1 - 0.0059 14.8 0.3 0.0067 14.6 0.3 1.0 1 0 0 1 1 1 1 DNA polymerase phi SUIM_assoc PF16619.5 CDJ45184.1 - 1.9 8.6 14.0 3.5 7.7 9.4 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ45184.1 - 3.6 7.5 11.9 4.5 7.2 11.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CW PF07496.15 CDJ45185.1 - 2.7e-16 59.3 5.5 6.3e-16 58.1 5.5 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger TMEM215 PF15746.5 CDJ45186.1 - 0.19 11.1 5.9 0.22 10.9 5.9 1.0 1 0 0 1 1 1 0 TMEM215 family DUF3381 PF11861.8 CDJ45186.1 - 2.7 7.8 9.9 3.3 7.5 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) AAA PF00004.29 CDJ45187.1 - 3.7e-08 33.9 0.1 2.4e-07 31.2 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ45187.1 - 0.0013 19.0 1.5 0.028 14.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDJ45187.1 - 0.0045 17.5 0.5 0.017 15.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CDJ45187.1 - 0.0071 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ45187.1 - 0.0078 16.2 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 CDJ45187.1 - 0.0084 16.6 11.5 0.23 12.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 CDJ45187.1 - 0.01 16.0 0.0 0.01 16.0 0.0 3.3 4 0 0 4 4 3 1 AAA domain Zeta_toxin PF06414.12 CDJ45187.1 - 0.01 15.1 0.2 0.01 15.1 0.2 1.9 2 0 0 2 2 1 0 Zeta toxin Rad17 PF03215.15 CDJ45187.1 - 0.01 15.7 0.0 0.037 14.0 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_16 PF13191.6 CDJ45187.1 - 0.02 15.3 1.5 0.02 15.3 1.5 4.3 2 2 1 3 3 1 0 AAA ATPase domain TsaE PF02367.17 CDJ45187.1 - 0.024 14.6 0.7 0.46 10.5 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CDJ45187.1 - 0.026 14.1 0.1 0.026 14.1 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CDJ45187.1 - 0.071 12.9 0.2 0.16 11.7 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CDJ45187.1 - 0.084 12.9 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CDJ45187.1 - 0.085 13.3 0.2 0.085 13.3 0.2 3.2 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 CDJ45187.1 - 0.19 11.6 0.1 0.37 10.7 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 CDJ45187.1 - 0.52 10.0 1.5 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain GvpK PF05121.12 CDJ45187.1 - 0.62 10.1 10.5 1.9 8.6 10.5 1.8 1 0 0 1 1 1 0 Gas vesicle protein K AAA_28 PF13521.6 CDJ45187.1 - 0.63 10.3 0.1 0.63 10.3 0.1 4.2 4 1 0 4 4 4 0 AAA domain NACHT PF05729.12 CDJ45187.1 - 1.7 8.5 7.0 2.1 8.2 0.3 3.2 3 0 0 3 3 3 0 NACHT domain DUF1980 PF09323.10 CDJ45189.1 - 0.75 9.7 5.2 18 5.2 4.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) tRNA-synt_2b PF00587.25 CDJ45190.1 - 2.9e-08 33.9 0.0 3.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF3446 PF11928.8 CDJ45190.1 - 0.0064 16.8 12.7 0.58 10.5 0.3 2.3 2 0 0 2 2 2 2 Early growth response N-terminal domain SR-25 PF10500.9 CDJ45190.1 - 0.47 10.0 28.1 0.86 9.2 3.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ45190.1 - 1.7 9.4 23.0 0.88 10.3 1.7 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein CCDC24 PF15669.5 CDJ45190.1 - 4.8 7.0 6.7 15 5.3 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family SR-25 PF10500.9 CDJ45191.1 - 0.24 11.0 31.0 0.42 10.2 30.8 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1645 PF07816.11 CDJ45191.1 - 1.1 9.8 20.9 1.8 9.1 20.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) MMR1 PF08505.10 CDJ45191.1 - 1.1 9.4 30.1 1.4 9.2 30.1 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GREB1 PF15782.5 CDJ45191.1 - 1.6 5.7 25.7 1.7 5.7 25.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ45191.1 - 3.5 7.1 29.8 4.1 6.9 29.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ45191.1 - 8 4.9 21.6 8.3 4.8 21.6 1.0 1 0 0 1 1 1 0 Macoilin family XRN_M PF17846.1 CDJ45191.1 - 9.4 5.1 18.2 10 4.9 18.2 1.0 1 0 0 1 1 1 0 Xrn1 helical domain RskA PF10099.9 CDJ45192.1 - 0.011 16.0 4.0 0.011 16.0 4.0 3.3 2 1 1 3 3 3 0 Anti-sigma-K factor rskA MLANA PF14991.6 CDJ45192.1 - 0.031 14.6 3.3 5.1 7.4 0.3 3.1 1 1 0 2 2 2 0 Protein melan-A CSG2 PF16965.5 CDJ45192.1 - 1.1 8.2 4.8 3.7 6.4 4.8 1.9 1 1 0 1 1 1 0 Ceramide synthase regulator DUF2371 PF10177.9 CDJ45192.1 - 1.8 8.7 4.4 4.1 7.6 0.1 2.9 3 1 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) KASH PF10541.9 CDJ45192.1 - 2.4 8.5 7.3 1.7 8.9 3.8 2.6 2 0 0 2 2 2 0 Nuclear envelope localisation domain UPRTase PF14681.6 CDJ45194.1 - 2.1e-34 118.8 0.0 2.3e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CDJ45194.1 - 1.7e-07 30.9 0.0 1.9e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MCPVI PF02993.14 CDJ45195.1 - 0.25 11.1 0.1 0.37 10.6 0.1 1.2 1 0 0 1 1 1 0 Minor capsid protein VI AP2 PF00847.20 CDJ45198.1 - 6.7e-05 23.0 2.5 6.7e-05 23.0 2.5 2.3 2 0 0 2 2 2 1 AP2 domain Miga PF10265.9 CDJ45201.1 - 2.2 7.2 5.1 3.5 6.5 5.1 1.3 1 0 0 1 1 1 0 Mitoguardin Ras PF00071.22 CDJ45202.1 - 4.7e-57 192.1 0.0 5.5e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ45202.1 - 2.2e-32 111.8 0.0 3e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ45202.1 - 1.2e-14 54.1 0.0 1.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ45202.1 - 8.6e-06 25.8 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ45202.1 - 8.7e-06 25.4 0.1 0.00088 18.9 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDJ45202.1 - 0.00039 19.9 0.0 0.00049 19.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 CDJ45202.1 - 0.0027 17.5 0.0 0.32 10.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CDJ45202.1 - 0.0032 17.4 0.0 1.8 8.4 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase SRPRB PF09439.10 CDJ45202.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CDJ45202.1 - 0.038 13.5 0.0 0.41 10.2 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 CDJ45202.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 CDJ45202.1 - 0.065 13.5 0.0 0.26 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 CDJ45202.1 - 0.084 12.0 0.0 0.18 10.9 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 CDJ45202.1 - 0.11 12.2 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CDJ45202.1 - 0.18 12.3 0.1 0.46 11.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Ras PF00071.22 CDJ45203.1 - 7.5e-40 136.2 0.0 8.8e-40 135.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ45203.1 - 2e-31 108.7 0.0 2.3e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ45203.1 - 3e-11 43.1 0.0 3.6e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ45203.1 - 3.9e-05 23.1 0.0 4.7e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ45203.1 - 0.00011 22.3 0.0 0.00014 21.9 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ45203.1 - 0.0013 18.3 0.0 0.0044 16.6 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CDJ45203.1 - 0.047 13.1 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 CDJ45203.1 - 0.082 12.3 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 CDJ45203.1 - 0.096 12.2 0.0 0.15 11.5 0.0 1.3 1 1 0 1 1 1 0 P-loop containing dynein motor region DGF-1_C PF11040.8 CDJ45204.1 - 0.94 9.5 5.5 14 5.7 0.2 3.4 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Glyco_hydro_31 PF01055.26 CDJ45207.1 - 5.9e-78 263.0 0.0 3.7e-72 243.9 0.0 2.5 2 1 0 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CDJ45207.1 - 4e-07 30.2 0.2 1.5e-06 28.4 0.2 1.9 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 CDJ45207.1 - 1.8e-06 28.1 0.0 3.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Rad1 PF02144.16 CDJ45208.1 - 0.062 12.4 0.1 0.11 11.6 0.1 1.4 1 1 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 SUIM_assoc PF16619.5 CDJ45208.1 - 0.093 12.8 9.8 0.058 13.5 1.9 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Not1 PF04054.15 CDJ45213.1 - 2.1 7.1 7.2 3.3 6.5 0.1 2.7 2 0 0 2 2 2 0 CCR4-Not complex component, Not1 ADSL_C PF10397.9 CDJ45213.1 - 3.6 8.2 8.2 0.24 12.0 0.7 3.2 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus WD40 PF00400.32 CDJ45214.1 - 4.3e-07 30.5 8.2 0.0022 18.8 0.0 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat SIR2 PF02146.17 CDJ45215.1 - 1.4e-06 28.4 0.0 0.00072 19.5 0.0 3.6 3 0 0 3 3 3 1 Sir2 family LAG1-DNAbind PF09271.11 CDJ45215.1 - 0.00078 20.1 1.8 0.0062 17.2 0.2 2.8 2 0 0 2 2 2 1 LAG1, DNA binding DUF1917 PF08939.10 CDJ45215.1 - 1.6 8.6 5.3 0.17 11.7 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1917) PLAC8 PF04749.17 CDJ45217.1 - 2.4 9.2 4.5 46 5.1 1.6 3.0 2 0 0 2 2 2 0 PLAC8 family Rav1p_C PF12234.8 CDJ45218.1 - 2e-21 76.1 23.3 4.9e-17 61.6 0.5 5.1 6 0 0 6 6 6 3 RAVE protein 1 C terminal DUF3306 PF11748.8 CDJ45222.1 - 0.38 11.6 14.2 2.2 9.2 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Surface_antigen PF11054.8 CDJ45223.1 - 1.8e-30 106.4 0.6 2.3e-30 106.1 0.6 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Asp_protease PF09668.10 CDJ45224.1 - 1.2e-49 167.2 0.0 3.9e-49 165.6 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ45224.1 - 1.1e-18 67.6 0.0 3e-18 66.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 CDJ45224.1 - 6.6e-10 38.6 0.0 1.8e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.6 CDJ45224.1 - 2.7e-07 31.1 0.0 8.5e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CDJ45224.1 - 0.00013 21.8 0.3 0.00062 19.5 0.3 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 CDJ45224.1 - 0.00098 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.20 CDJ45224.1 - 0.065 13.5 0.0 0.28 11.5 0.0 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease SUIM_assoc PF16619.5 CDJ45224.1 - 0.15 12.1 0.3 0.15 12.1 0.3 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TetR_C_9 PF14514.6 CDJ45224.1 - 3.5 7.8 5.2 1.7 8.7 0.4 2.6 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain ATP-synt_C PF00137.21 CDJ45225.1 - 4.1e-07 30.2 7.6 4.1e-07 30.2 7.6 2.3 2 0 0 2 2 2 1 ATP synthase subunit C ENTH PF01417.20 CDJ45226.1 - 9.4e-28 96.8 0.0 1.9e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CDJ45226.1 - 0.24 10.4 0.0 0.24 10.4 0.0 2.1 2 0 0 2 2 2 0 ANTH domain TFIIA PF03153.13 CDJ45227.1 - 0.014 15.4 6.1 0.017 15.1 6.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DcrB PF08786.11 CDJ45227.1 - 0.041 14.0 3.3 0.041 14.0 3.3 1.9 2 0 0 2 2 2 0 DcrB SUIM_assoc PF16619.5 CDJ45227.1 - 0.054 13.6 20.4 0.98 9.5 2.7 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 M_domain PF12938.7 CDJ45227.1 - 0.067 13.0 18.6 0.62 9.8 9.2 2.2 2 0 0 2 2 2 0 M domain of GW182 Hydin_ADK PF17213.3 CDJ45227.1 - 0.5 10.6 3.1 0.27 11.5 1.4 1.4 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain Seryl_tRNA_N PF02403.22 CDJ45228.1 - 0.79 10.0 9.9 6.3 7.1 9.9 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.19 CDJ45229.1 - 1.2e-187 625.5 0.1 1.3e-187 625.3 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HemY_N PF07219.13 CDJ45229.1 - 0.017 15.3 1.5 0.017 15.3 1.5 3.5 3 1 1 4 4 4 0 HemY protein N-terminus DUF1180 PF06679.12 CDJ45229.1 - 0.03 14.7 0.5 0.061 13.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2561 PF10812.8 CDJ45229.1 - 0.041 13.9 0.8 0.085 12.9 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Spore_coat_CotO PF14153.6 CDJ45229.1 - 0.074 13.0 0.4 0.11 12.4 0.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CCDC53 PF10152.9 CDJ45229.1 - 0.091 13.2 0.9 0.16 12.4 0.9 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex COX_ARM PF06481.14 CDJ45229.1 - 0.12 12.3 0.2 0.45 10.5 0.1 2.0 2 0 0 2 2 2 0 COX Aromatic Rich Motif ISK_Channel PF02060.15 CDJ45229.1 - 6.1 6.6 5.3 10 5.8 0.4 3.3 3 0 0 3 3 3 0 Slow voltage-gated potassium channel V_ATPase_I PF01496.19 CDJ45230.1 - 4.1e-50 170.6 0.0 8.2e-50 169.6 0.0 1.4 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family Spt20 PF12090.8 CDJ45230.1 - 0.078 12.6 14.4 0.12 11.9 12.4 2.0 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 CDJ45230.1 - 1.1 9.4 27.5 7.3 6.7 8.0 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ45230.1 - 1.8 8.5 18.2 0.86 9.5 12.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ45231.1 - 0.018 15.6 4.4 0.018 15.6 4.4 3.2 4 0 0 4 4 4 0 60s Acidic ribosomal protein DUF3446 PF11928.8 CDJ45231.1 - 0.33 11.3 12.5 0.3 11.4 8.0 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF1908 PF08926.11 CDJ45231.1 - 1.1 8.2 6.6 1.9 7.5 6.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1908) DUF3138 PF11336.8 CDJ45231.1 - 3.9 6.0 13.8 0.083 11.5 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Exo_endo_phos PF03372.23 CDJ45233.1 - 1.3e-05 24.8 0.0 0.19 11.2 0.0 2.7 1 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Med15 PF09606.10 CDJ45233.1 - 0.00033 19.5 45.3 0.00044 19.1 45.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal GET2 PF08690.10 CDJ45233.1 - 0.0016 18.2 10.6 0.0016 18.2 10.6 2.1 2 0 0 2 2 2 1 GET complex subunit GET2 PAT1 PF09770.9 CDJ45233.1 - 2.6 6.2 19.8 3.3 5.9 19.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 CDJ45233.1 - 3.5 6.3 17.4 2.2 7.0 0.4 2.1 2 0 0 2 2 2 0 Presenilin TSSC4 PF15264.6 CDJ45234.1 - 0.043 14.1 0.5 0.098 12.9 0.0 1.8 2 0 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 AAA_23 PF13476.6 CDJ45234.1 - 0.045 14.2 0.0 0.049 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain FmiP_Thoc5 PF09766.9 CDJ45234.1 - 8.6 5.5 10.0 0.17 11.1 2.6 1.7 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Gpi1 PF05024.15 CDJ45235.1 - 2.1e-23 83.4 5.9 3.4e-23 82.7 5.9 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) SR-25 PF10500.9 CDJ45235.1 - 1.3 8.6 7.2 1.8 8.1 7.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HSP90 PF00183.18 CDJ45237.1 - 4e-82 276.8 4.7 6.4e-82 276.1 4.7 1.3 1 0 0 1 1 1 1 Hsp90 protein DUF2722 PF10846.8 CDJ45237.1 - 0.0025 16.9 13.0 0.0046 16.0 5.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) EFF-AFF PF14884.6 CDJ45237.1 - 0.28 9.3 0.7 0.47 8.5 0.7 1.3 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen Spt20 PF12090.8 CDJ45237.1 - 0.43 10.2 20.5 0.1 12.2 5.7 2.2 2 0 0 2 2 2 0 Spt20 family FliD_N PF02465.18 CDJ45237.1 - 1.9 9.2 8.5 5.1 7.9 0.4 2.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF1525 PF07511.11 CDJ45237.1 - 4.2 7.5 14.0 0.38 10.9 4.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) HEAT PF02985.22 CDJ45239.1 - 1.1e-05 25.3 5.2 0.012 15.8 0.2 4.4 3 0 0 3 3 3 2 HEAT repeat Pkinase PF00069.25 CDJ45239.1 - 2.8e-05 23.6 0.0 0.00027 20.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain UNC45-central PF11701.8 CDJ45239.1 - 0.071 13.1 2.3 0.11 12.4 0.7 2.1 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central Arm PF00514.23 CDJ45239.1 - 0.34 11.0 0.1 0.34 11.0 0.1 3.8 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat IFRD PF05004.13 CDJ45239.1 - 0.74 8.9 6.8 1.8 7.6 0.4 3.2 2 1 1 3 3 3 0 Interferon-related developmental regulator (IFRD) TFIIA PF03153.13 CDJ45240.1 - 0.0099 15.9 21.3 0.013 15.6 21.3 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cas_TM1802 PF09484.10 CDJ45240.1 - 0.04 12.7 0.8 0.055 12.2 0.8 1.2 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) SARAF PF06682.12 CDJ45240.1 - 0.45 10.1 8.2 0.56 9.8 8.2 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4175 PF13779.6 CDJ45240.1 - 0.63 7.9 26.7 0.88 7.4 26.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Presenilin PF01080.17 CDJ45240.1 - 2.2 7.0 9.1 2.6 6.7 9.1 1.1 1 0 0 1 1 1 0 Presenilin AA_kinase PF00696.28 CDJ45241.1 - 2.4e-13 50.3 0.2 1.8e-12 47.4 0.2 2.2 1 1 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 CDJ45241.1 - 5e-13 48.8 0.0 8.8e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 PUA domain Ribosomal_60s PF00428.19 CDJ45241.1 - 0.00074 20.1 8.7 0.00074 20.1 8.7 4.1 3 1 1 4 4 4 1 60s Acidic ribosomal protein Sec3_C PF09763.9 CDJ45241.1 - 0.57 8.5 1.9 0.87 7.9 1.9 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 Ras PF00071.22 CDJ45242.1 - 4.6e-09 36.1 0.5 6.1e-09 35.7 0.5 1.2 1 0 0 1 1 1 1 Ras family NOB1_Zn_bind PF08772.11 CDJ45242.1 - 0.08 13.1 0.1 0.33 11.2 0.2 1.9 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like PMD PF10536.9 CDJ45242.1 - 0.26 10.4 1.6 0.33 10.0 1.6 1.1 1 0 0 1 1 1 0 Plant mobile domain Dmrt1 PF12374.8 CDJ45242.1 - 5.2 7.6 13.2 6.9 7.2 10.7 2.1 1 1 1 2 2 2 0 Double-sex mab3 related transcription factor 1 Herpes_pp85 PF04637.12 CDJ45242.1 - 8.1 4.7 5.4 7.9 4.8 5.4 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3138 PF11336.8 CDJ45242.1 - 9 4.8 14.3 9.9 4.6 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Dehydrin PF00257.19 CDJ45243.1 - 0.013 16.0 1.7 0.013 16.0 1.7 6.0 6 1 0 6 6 6 0 Dehydrin CPSF73-100_C PF11718.8 CDJ45243.1 - 0.044 13.3 2.1 0.11 12.0 2.1 1.7 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term HCO3_cotransp PF00955.21 CDJ45244.1 - 0.01 14.7 0.2 0.01 14.7 0.2 2.2 2 1 1 3 3 3 0 HCO3- transporter family Peroxin-13_N PF04088.13 CDJ45244.1 - 0.012 15.9 1.0 0.012 15.9 1.0 4.9 4 0 0 4 4 4 0 Peroxin 13, N-terminal region 7tm_2 PF00002.24 CDJ45244.1 - 0.026 13.8 0.3 0.066 12.5 0.3 1.6 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Gaa1 PF04114.14 CDJ45244.1 - 0.54 9.2 9.1 0.2 10.6 2.7 2.4 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component Sprouty PF05210.13 CDJ45244.1 - 1.4 9.4 5.3 4.9 7.6 0.0 3.5 3 0 0 3 3 3 0 Sprouty protein (Spry) COX14 PF14880.6 CDJ45245.1 - 0.056 13.3 0.7 0.09 12.6 0.7 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Spt20 PF12090.8 CDJ45245.1 - 1.5 8.4 8.7 2.3 7.7 8.7 1.3 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ45247.1 - 3.1e-15 56.0 0.1 0.003 17.6 0.0 4.1 2 2 1 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 SET PF00856.28 CDJ45247.1 - 2.6e-12 47.5 0.1 2.6e-12 47.5 0.1 4.0 3 3 0 3 3 3 1 SET domain K_channel_TID PF07941.11 CDJ45247.1 - 0.012 16.1 11.4 0.012 16.1 11.4 8.9 5 3 2 7 7 7 0 Potassium channel Kv1.4 tandem inactivation domain TFIIA PF03153.13 CDJ45247.1 - 0.84 9.6 49.0 0.19 11.7 31.5 2.2 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Kelch_1 PF01344.25 CDJ45249.1 - 1e-31 108.2 0.1 3.5e-10 39.3 0.0 3.3 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 CDJ45249.1 - 3e-28 97.1 0.0 1.9e-09 37.5 0.0 3.1 1 1 2 3 3 3 3 Kelch motif Kelch_4 PF13418.6 CDJ45249.1 - 7e-21 74.0 0.0 1.3e-09 37.9 0.0 3.1 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ45249.1 - 8.4e-13 48.3 0.8 8.8e-06 25.9 0.1 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ45249.1 - 8.1e-11 41.7 0.1 0.00019 21.3 0.0 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CDJ45249.1 - 7.4e-10 38.4 0.0 0.008 16.1 0.0 3.5 3 0 0 3 3 3 3 Kelch motif DUF1668 PF07893.13 CDJ45249.1 - 0.00068 19.1 0.0 0.1 11.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1668) DUF1918 PF08940.11 CDJ45249.1 - 0.024 14.3 0.0 0.064 12.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) TPALS PF18178.1 CDJ45249.1 - 0.061 12.8 0.0 0.11 11.9 0.0 1.4 2 0 0 2 2 2 0 TIR- and PNP-associating SLOG family CBF PF03914.17 CDJ45250.1 - 9.9e-28 97.3 0.6 9.9e-28 97.3 0.6 3.1 3 1 0 3 3 3 1 CBF/Mak21 family BAG6 PF12057.8 CDJ45250.1 - 0.036 13.8 0.1 0.036 13.8 0.1 2.8 3 0 0 3 3 3 0 BCL2-associated athanogene 6 TFIIA PF03153.13 CDJ45250.1 - 5.9 6.8 45.8 6.7 6.6 37.9 2.3 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit EOS1 PF12326.8 CDJ45250.1 - 8.5 6.3 7.3 2.5 8.0 0.5 2.5 3 0 0 3 3 3 0 N-glycosylation protein Aquarius_N PF16399.5 CDJ45251.1 - 4.5 5.2 13.8 7.3 4.5 13.8 1.2 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus Ank_4 PF13637.6 CDJ45252.1 - 1.6e-18 66.8 2.2 7.6e-08 32.8 0.0 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ45252.1 - 1.7e-18 67.0 1.6 1.6e-07 31.8 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) RNA_GG_bind PF10258.9 CDJ45252.1 - 1.9e-18 66.2 0.0 3.9e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 PHAX RNA-binding domain Ank_3 PF13606.6 CDJ45252.1 - 2.7e-11 42.6 0.5 0.04 14.5 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 CDJ45252.1 - 1.9e-10 40.7 5.9 0.0012 19.2 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CDJ45252.1 - 3.9e-07 30.2 3.8 0.031 14.6 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ribosomal_60s PF00428.19 CDJ45253.1 - 0.025 15.2 6.7 0.025 15.2 6.7 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ45253.1 - 0.16 12.3 8.4 0.19 12.0 8.4 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Zea_mays_MuDR PF05928.11 CDJ45253.1 - 2.9 7.5 3.8 3.6 7.2 3.8 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) CbiD PF01888.17 CDJ45253.1 - 3.8 6.7 5.1 5.5 6.2 5.1 1.3 1 0 0 1 1 1 0 CbiD TALPID3 PF15324.6 CDJ45253.1 - 9.9 3.7 7.4 10 3.6 7.4 1.0 1 0 0 1 1 1 0 Hedgehog signalling target CECR6_TMEM121 PF14997.6 CDJ45255.1 - 8.5e-13 48.6 0.7 9.1e-08 32.2 0.0 2.6 3 0 0 3 3 3 2 CECR6/TMEM121 family DUF4184 PF13803.6 CDJ45255.1 - 7.8 6.1 9.7 0.85 9.3 1.5 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4184) Spt20 PF12090.8 CDJ45255.1 - 8.5 5.9 8.4 13 5.3 8.4 1.2 1 0 0 1 1 1 0 Spt20 family CKS PF01111.19 CDJ45256.1 - 0.08 13.2 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase regulatory subunit HEAT PF02985.22 CDJ45257.1 - 0.16 12.3 1.2 6.7 7.3 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat Ank_3 PF13606.6 CDJ45258.1 - 1.3e-09 37.5 0.2 0.018 15.6 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 CDJ45258.1 - 6.8e-09 35.8 1.2 0.01 16.3 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 CDJ45258.1 - 7.5e-09 36.1 0.1 1.1e-06 29.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ45258.1 - 1.1e-07 32.3 0.2 9.7e-06 26.0 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ45258.1 - 1.4e-06 28.4 1.3 0.0016 18.7 0.2 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) ABC_tran PF00005.27 CDJ45261.1 - 3e-11 44.0 0.3 6.4e-11 42.9 0.0 1.6 2 0 0 2 2 2 1 ABC transporter SR-25 PF10500.9 CDJ45261.1 - 0.0092 15.6 12.4 0.012 15.3 12.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein ABC_ATPase PF09818.9 CDJ45261.1 - 0.031 13.1 0.0 0.067 12.0 0.0 1.5 1 1 0 1 1 1 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 CDJ45261.1 - 0.038 14.2 0.3 0.038 14.2 0.3 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RAP1 PF07218.11 CDJ45261.1 - 3.3 5.9 3.6 3.3 5.9 3.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Herpes_pp85 PF04637.12 CDJ45261.1 - 5 5.4 6.2 5.9 5.2 6.2 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) RskA PF10099.9 CDJ45264.1 - 0.48 10.7 37.8 0.41 10.9 1.3 3.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Keratin_2_head PF16208.5 CDJ45264.1 - 0.79 9.8 5.4 0.11 12.7 0.9 1.8 2 0 0 2 2 2 0 Keratin type II head eIF-3_zeta PF05091.12 CDJ45264.1 - 5.2 5.9 19.5 4.7 6.1 1.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4614 PF15391.6 CDJ45265.1 - 4.9 7.1 12.8 5 7.1 12.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) API5 PF05918.11 CDJ45266.1 - 0.076 11.8 0.1 1.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) G6PD_N PF00479.22 CDJ45268.1 - 2.6e-55 187.8 0.0 5.5e-55 186.7 0.0 1.5 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Glucosamine_iso PF01182.20 CDJ45268.1 - 4.4e-38 131.4 0.0 9.8e-38 130.3 0.0 1.6 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase G6PD_C PF02781.16 CDJ45268.1 - 1.3e-09 37.7 0.1 2e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Myb_DNA-bind_5 PF13873.6 CDJ45268.1 - 0.082 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain NAD_synthase PF02540.17 CDJ45268.1 - 0.14 11.3 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Myb_DNA-bind_4 PF13837.6 CDJ45268.1 - 0.14 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain TipAS PF07739.13 CDJ45268.1 - 0.18 12.4 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain SRP-alpha_N PF04086.13 CDJ45270.1 - 5.5 6.8 25.4 1.3 8.9 6.5 2.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Ank_3 PF13606.6 CDJ45271.1 - 9.7e-19 65.5 1.0 0.0001 22.4 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 CDJ45271.1 - 2e-18 66.8 4.0 3e-15 56.6 0.7 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ45271.1 - 2.9e-17 62.8 1.1 1.4e-10 41.5 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ45271.1 - 3.3e-15 55.7 6.3 8.7e-06 26.0 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CDJ45271.1 - 1.2e-14 54.1 1.2 1.9e-07 31.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF1635 PF07795.11 CDJ45272.1 - 1.6 8.5 6.9 2 8.2 6.5 1.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) TFIIA PF03153.13 CDJ45272.1 - 7.9 6.4 14.2 9.3 6.1 14.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_5 PF13857.6 CDJ45273.1 - 0.00091 19.5 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ45273.1 - 0.021 15.4 0.0 0.028 15.0 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) B12-binding_2 PF02607.17 CDJ45273.1 - 0.11 13.0 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain FTZ PF03867.14 CDJ45274.1 - 0.0047 16.5 8.7 0.0047 16.5 8.7 2.5 2 1 0 2 2 2 1 Fushi tarazu (FTZ), N-terminal region SR-25 PF10500.9 CDJ45274.1 - 0.013 15.1 9.6 0.013 15.1 9.6 2.9 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ45274.1 - 0.25 10.9 20.7 1.3 8.6 3.9 2.2 2 0 0 2 2 2 0 Spt20 family CIAPIN1 PF05093.13 CDJ45274.1 - 3.8 8.1 12.1 1.4 9.5 7.3 2.5 1 1 1 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Roughex PF06020.11 CDJ45274.1 - 7 5.6 11.7 1.7 7.7 3.3 2.4 2 0 0 2 2 2 0 Drosophila roughex protein ISP3_C PF18045.1 CDJ45275.1 - 9.6e-37 125.2 0.0 1.2e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 ISP3 C-terminal ISP1_C PF18161.1 CDJ45275.1 - 2.8e-23 81.9 0.0 3.5e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 ISP1 C-terminal SelK_SelG PF10961.8 CDJ45275.1 - 0.26 11.9 6.9 0.53 10.9 6.9 1.5 1 1 0 1 1 1 0 Selenoprotein SelK_SelG Chorion_3 PF05387.11 CDJ45275.1 - 9.2 5.8 17.0 13 5.4 17.0 1.2 1 0 0 1 1 1 0 Chorion family 3 RmlD_sub_bind PF04321.17 CDJ45276.1 - 4e-107 357.6 1.0 4.4e-107 357.4 1.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 CDJ45276.1 - 4.2e-26 91.9 0.1 5.3e-26 91.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDJ45276.1 - 5.3e-14 51.9 0.8 6.8e-14 51.5 0.4 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CDJ45276.1 - 1.8e-13 50.6 0.5 2.7e-12 46.8 0.0 2.1 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CDJ45276.1 - 7.4e-13 48.3 3.5 1.4e-11 44.1 1.0 2.9 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CDJ45276.1 - 2.8e-11 43.1 0.3 1.2e-10 41.0 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein KR PF08659.10 CDJ45276.1 - 0.013 15.5 2.3 0.077 12.9 2.3 2.0 1 1 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 CDJ45276.1 - 0.02 15.3 0.2 0.22 12.0 0.1 2.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 CDJ45276.1 - 0.057 13.0 0.2 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 CDJ45277.1 - 4.7e-73 246.5 0.0 6.4e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDJ45277.1 - 9.1e-62 208.7 0.0 1.2e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CDJ45277.1 - 6.1e-16 58.4 0.0 3.8e-15 55.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 CDJ45277.1 - 8.1e-13 48.0 0.0 1.1e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CDJ45277.1 - 2.1e-11 43.5 0.0 3.9e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CDJ45277.1 - 9e-11 41.4 0.0 1.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 CDJ45277.1 - 8e-05 22.3 0.7 0.00021 20.9 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 CDJ45277.1 - 0.00014 21.8 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CDJ45277.1 - 0.0002 20.9 0.2 0.0034 16.9 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 CDJ45277.1 - 0.0009 19.5 0.1 0.0019 18.5 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 CDJ45277.1 - 0.0083 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NTP_transferase PF00483.23 CDJ45278.1 - 2.4e-63 214.0 0.0 2.9e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CDJ45278.1 - 6.2e-05 23.4 0.0 7.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain M60-like_N PF17291.2 CDJ45278.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases Pro_isomerase PF00160.21 CDJ45280.1 - 3.1e-05 24.3 0.0 4.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RAP1 PF07218.11 CDJ45280.1 - 6.8 4.8 5.7 7.6 4.7 5.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) KOW PF00467.29 CDJ45281.1 - 0.00085 19.2 0.0 0.39 10.7 0.0 2.4 2 0 0 2 2 2 2 KOW motif Neuropeptide_S PF14993.6 CDJ45281.1 - 0.011 15.6 0.6 0.091 12.6 0.0 2.5 3 0 0 3 3 3 0 Neuropeptide S precursor protein Peptidase_S8 PF00082.22 CDJ45282.1 - 0.19 11.0 4.3 0.22 10.7 4.3 1.1 1 0 0 1 1 1 0 Subtilase family SR-25 PF10500.9 CDJ45282.1 - 1.1 8.8 6.1 1.8 8.1 6.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ45283.1 - 0.0048 16.9 12.8 0.0048 16.9 12.8 3.8 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 Herpes_UL74 PF07982.12 CDJ45283.1 - 0.18 10.8 2.2 0.31 10.0 2.2 1.3 1 0 0 1 1 1 0 Herpes UL74 glycoproteins Spt20 PF12090.8 CDJ45283.1 - 0.35 10.4 38.1 0.28 10.8 11.3 3.2 3 0 0 3 3 3 0 Spt20 family RskA PF10099.9 CDJ45285.1 - 0.19 12.0 18.7 0.27 11.5 18.7 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA FAST_1 PF06743.15 CDJ45286.1 - 0.011 15.7 4.3 0.29 11.1 0.4 2.9 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 5_nucleotid PF05761.14 CDJ45286.1 - 0.024 13.5 3.7 0.048 12.6 3.7 1.5 1 0 0 1 1 1 0 5' nucleotidase family RAP PF08373.10 CDJ45286.1 - 0.052 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 RAP domain WH2 PF02205.20 CDJ45289.1 - 0.011 15.6 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 0 WH2 motif Polysacc_deac_1 PF01522.21 CDJ45289.1 - 0.11 12.4 0.3 0.12 12.3 0.3 1.0 1 0 0 1 1 1 0 Polysaccharide deacetylase EF-hand_6 PF13405.6 CDJ45290.1 - 5e-14 51.0 0.1 2.9e-06 26.8 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDJ45290.1 - 6.8e-14 50.3 0.0 1.8e-06 27.1 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDJ45290.1 - 3.2e-10 40.3 0.0 0.00058 20.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ45290.1 - 7.2e-08 31.6 0.1 0.0013 18.1 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ45290.1 - 8.1e-07 28.8 0.0 0.015 15.2 0.2 3.4 3 1 0 3 3 3 2 EF-hand domain pair Caleosin PF05042.13 CDJ45290.1 - 0.00065 19.7 0.0 0.34 10.8 0.0 2.3 2 0 0 2 2 2 2 Caleosin related protein NRBF2 PF08961.10 CDJ45290.1 - 0.007 16.0 0.2 0.014 15.0 0.1 1.6 1 1 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator Toprim_2 PF13155.6 CDJ45290.1 - 0.0093 16.4 1.2 0.9 10.0 0.0 3.3 2 1 1 3 3 3 1 Toprim-like EF-hand_9 PF14658.6 CDJ45290.1 - 0.024 15.0 0.0 0.13 12.6 0.0 2.2 2 1 0 2 2 2 0 EF-hand domain DUF2383 PF09537.10 CDJ45290.1 - 0.081 13.3 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) ApbA_C PF08546.11 CDJ45290.1 - 0.15 12.3 0.0 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal DUF4064 PF13273.6 CDJ45290.1 - 0.21 11.9 0.1 1.2 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) RskA PF10099.9 CDJ45290.1 - 0.66 10.2 19.3 0.11 12.8 9.7 2.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA PAT1 PF09770.9 CDJ45290.1 - 1.2 7.3 15.4 1.6 6.9 15.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.19 CDJ45290.1 - 5.1 7.7 15.6 20 5.9 8.5 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Lin-8 PF03353.15 CDJ45291.1 - 0.78 9.2 35.8 1.2 8.7 35.8 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SAPS PF04499.15 CDJ45291.1 - 7.8 5.1 23.7 8.7 5.0 23.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TNFR_c6 PF00020.18 CDJ45292.1 - 0.00027 21.3 22.9 0.016 15.6 1.2 5.9 4 2 1 5 5 5 3 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 CDJ45292.1 - 0.094 12.5 39.6 1.1 9.0 1.9 6.3 2 1 3 5 5 5 0 Putative ephrin-receptor like Trypan_PARP PF05887.11 CDJ45293.1 - 0.35 10.8 18.0 0.04 13.9 11.4 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) RskA PF10099.9 CDJ45294.1 - 0.0045 17.3 3.2 0.0045 17.3 3.2 8.5 4 2 3 7 7 7 2 Anti-sigma-K factor rskA UDPGP PF01704.18 CDJ45295.1 - 7.9e-09 34.6 0.0 1.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4207 PF13904.6 CDJ45297.1 - 0.45 10.2 13.6 0.53 9.9 13.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) EOS1 PF12326.8 CDJ45299.1 - 1.7 8.5 7.1 1.8 8.4 7.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein TFIIA PF03153.13 CDJ45299.1 - 2.5 8.0 23.8 2.6 8.0 23.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 CDJ45299.1 - 2.7 7.7 7.6 2.7 7.7 7.6 1.1 1 0 0 1 1 1 0 Connexin Ureide_permease PF07168.11 CDJ45299.1 - 4.3 6.0 5.0 4.3 6.0 5.0 1.0 1 0 0 1 1 1 0 Ureide permease CLN3 PF02487.17 CDJ45299.1 - 6 5.8 7.8 5.7 5.9 7.8 1.0 1 0 0 1 1 1 0 CLN3 protein Spt20 PF12090.8 CDJ45299.1 - 7.6 6.1 28.5 8.5 5.9 28.5 1.0 1 0 0 1 1 1 0 Spt20 family Med15 PF09606.10 CDJ45300.1 - 3.6 6.1 81.4 0.078 11.7 13.1 3.2 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Gti1_Pac2 PF09729.9 CDJ45300.1 - 5.2 7.1 12.2 6.4 6.8 1.1 3.1 3 0 0 3 3 3 0 Gti1/Pac2 family Methyltransf_31 PF13847.6 CDJ45301.1 - 4.3e-13 49.3 0.0 5.1e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ45301.1 - 4.9e-11 43.2 0.0 8.6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ45301.1 - 5.1e-11 43.1 0.0 7.4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ45301.1 - 2.8e-09 37.6 0.0 4.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ45301.1 - 5.7e-08 32.8 0.0 8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ45301.1 - 0.00031 20.2 0.0 0.00041 19.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 CDJ45301.1 - 0.0052 16.4 0.0 0.0066 16.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.11 CDJ45301.1 - 0.0055 16.4 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 CDJ45301.1 - 0.039 13.3 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 CDJ45301.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase small domain Peptidase_M16_M PF16187.5 CDJ45302.1 - 1.5e-07 31.0 0.1 0.0033 16.8 0.4 2.4 2 0 0 2 2 2 2 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CDJ45302.1 - 1.1e-06 28.8 0.2 0.023 14.7 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Vitellogenin_N PF01347.22 CDJ45302.1 - 0.021 13.2 5.5 0.032 12.7 5.5 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region DUF2232 PF09991.9 CDJ45302.1 - 0.27 10.4 0.8 0.53 9.4 0.8 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SbcCD_C PF13558.6 CDJ45302.1 - 1.9 8.8 8.6 0.42 10.9 3.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Spt20 PF12090.8 CDJ45302.1 - 8.8 5.9 11.5 14 5.2 1.0 2.5 2 0 0 2 2 2 0 Spt20 family Peptidase_S8 PF00082.22 CDJ45303.1 - 3.1e-23 82.5 15.6 4.6e-23 81.9 15.6 1.2 1 0 0 1 1 1 1 Subtilase family DUF2201_N PF13203.6 CDJ45303.1 - 0.033 13.8 2.2 0.074 12.6 2.2 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain Rrn6 PF10214.9 CDJ45304.1 - 0.015 13.8 4.1 0.016 13.8 4.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Inj_translocase PF16928.5 CDJ45304.1 - 0.026 14.0 8.0 0.034 13.6 8.0 1.2 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome Ctr PF04145.15 CDJ45304.1 - 0.05 14.2 0.1 0.059 14.0 0.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Presenilin PF01080.17 CDJ45304.1 - 0.078 11.7 0.7 0.081 11.7 0.7 1.1 1 0 0 1 1 1 0 Presenilin DUF2514 PF10721.9 CDJ45304.1 - 0.67 10.0 9.8 0.9 9.6 9.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Spt20 PF12090.8 CDJ45304.1 - 1.6 8.3 13.4 2 7.9 13.4 1.1 1 0 0 1 1 1 0 Spt20 family SHR3_chaperone PF08229.11 CDJ45304.1 - 4.2 6.3 5.3 5.8 5.9 5.3 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 Rhabdo_M1 PF03342.13 CDJ45307.1 - 0.089 12.1 0.2 0.13 11.6 0.1 1.3 1 1 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) SNF PF00209.18 CDJ45312.1 - 0.00052 18.8 0.1 0.00084 18.2 0.1 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family EF-hand_4 PF12763.7 CDJ45313.1 - 3.3e-06 27.0 0.0 1e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CDJ45313.1 - 0.0039 16.6 0.0 0.0093 15.5 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CDJ45313.1 - 0.067 13.2 0.0 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain MORN PF02493.20 CDJ45314.1 - 3.5e-14 51.8 9.7 1.1e-06 28.1 1.1 4.1 4 0 0 4 4 4 3 MORN repeat Spt20 PF12090.8 CDJ45314.1 - 6 6.4 19.9 8.7 5.9 19.9 1.3 1 0 0 1 1 1 0 Spt20 family Ribosomal_L7Ae PF01248.26 CDJ45315.1 - 1.9e-23 82.0 0.0 2.2e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DPBB_1 PF03330.18 CDJ45315.1 - 0.074 13.3 0.0 3.7 7.9 0.0 2.1 1 1 0 2 2 2 0 Lytic transglycolase Hydrolase_6 PF13344.6 CDJ45315.1 - 0.084 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Pescadillo_N PF06732.11 CDJ45316.1 - 4.3e-46 157.7 9.7 4.9e-30 105.0 1.0 2.6 2 1 1 3 3 3 2 Pescadillo N-terminus TFIIA PF03153.13 CDJ45316.1 - 0.03 14.3 30.0 0.057 13.4 30.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tmemb_9 PF05434.11 CDJ45317.1 - 0.3 11.0 0.0 0.3 11.0 0.0 4.1 4 1 0 4 4 4 0 TMEM9 Peptidase_U57 PF05582.12 CDJ45318.1 - 0.082 12.2 0.3 0.082 12.2 0.3 2.2 2 0 0 2 2 2 0 YabG peptidase U57 DUF4407 PF14362.6 CDJ45318.1 - 2.6 7.3 34.5 0.029 13.8 6.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SR-25 PF10500.9 CDJ45318.1 - 7 6.2 33.7 0.43 10.2 14.4 2.6 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein CRM1_repeat_2 PF18784.1 CDJ45319.1 - 2.9e-11 42.9 0.2 3.5e-11 42.6 0.2 1.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat PF18777.1 CDJ45320.1 - 7.6e-09 34.9 0.3 9.1e-09 34.7 0.3 1.2 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat RIBIOP_C PF04950.12 CDJ45321.1 - 2.2e-27 96.2 0.0 2.2e-27 96.2 0.0 2.2 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal DUF4638 PF15472.6 CDJ45321.1 - 0.11 12.3 17.0 0.21 11.3 17.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Exonuc_VII_L PF02601.15 CDJ45321.1 - 0.27 10.8 13.4 0.44 10.1 13.4 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit DegT_DnrJ_EryC1 PF01041.17 CDJ45321.1 - 0.34 10.2 7.4 0.56 9.5 7.4 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DDHD PF02862.17 CDJ45321.1 - 0.53 10.4 10.5 0.86 9.7 10.5 1.3 1 0 0 1 1 1 0 DDHD domain LMBR1 PF04791.16 CDJ45321.1 - 1.9 7.3 3.8 2 7.2 3.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SUIM_assoc PF16619.5 CDJ45322.1 - 5.4e-08 32.8 0.1 0.00076 19.5 0.0 3.1 2 1 1 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 Filament PF00038.21 CDJ45322.1 - 0.0032 17.1 0.8 0.0056 16.3 0.8 1.3 1 0 0 1 1 1 1 Intermediate filament protein Phage_GP20 PF06810.11 CDJ45322.1 - 0.0071 16.2 0.5 0.013 15.3 0.5 1.4 1 0 0 1 1 1 1 Phage minor structural protein GP20 Lzipper-MIP1 PF14389.6 CDJ45322.1 - 0.052 13.9 1.5 0.052 13.9 1.5 2.7 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 BBP1_C PF15272.6 CDJ45322.1 - 0.067 13.0 0.2 0.067 13.0 0.2 1.6 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal DUF4407 PF14362.6 CDJ45322.1 - 0.27 10.6 3.2 2 7.7 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fmp27_WPPW PF10359.9 CDJ45322.1 - 0.58 9.0 2.6 0.26 10.1 0.2 1.5 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain PKcGMP_CC PF16808.5 CDJ45322.1 - 4.1 7.4 7.1 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Utp21 PF04192.12 CDJ45322.1 - 9.3 5.7 8.6 1.1 8.7 2.3 2.0 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain ABC_tran_CTD PF16326.5 CDJ45322.1 - 9.8 6.5 16.8 0.86 9.9 0.4 3.1 4 0 0 4 4 4 0 ABC transporter C-terminal domain RskA PF10099.9 CDJ45323.1 - 0.0015 18.9 8.7 0.002 18.5 8.7 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Coilin_N PF15862.5 CDJ45323.1 - 0.0019 18.0 6.2 0.0022 17.8 6.2 1.4 1 0 0 1 1 1 1 Coilin N-terminus Spore_coat_CotO PF14153.6 CDJ45323.1 - 0.0047 16.9 15.5 0.0047 16.9 15.5 1.1 1 0 0 1 1 1 1 Spore coat protein CotO CCDC53 PF10152.9 CDJ45323.1 - 0.0047 17.3 10.4 0.0059 17.0 10.4 1.2 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Myc_N PF01056.18 CDJ45323.1 - 0.007 16.3 8.2 0.0079 16.1 8.2 1.1 1 0 0 1 1 1 1 Myc amino-terminal region DUF4820 PF16091.5 CDJ45323.1 - 0.0077 15.6 7.6 0.0084 15.5 7.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) MID_MedPIWI PF18296.1 CDJ45323.1 - 0.023 14.5 8.0 0.024 14.5 8.0 1.1 1 0 0 1 1 1 0 MID domain of medPIWI Raftlin PF15250.6 CDJ45323.1 - 0.024 13.4 9.1 0.028 13.2 9.1 1.0 1 0 0 1 1 1 0 Raftlin V_ATPase_I PF01496.19 CDJ45323.1 - 0.034 12.1 7.0 0.036 12.0 7.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDHD PF02862.17 CDJ45323.1 - 0.034 14.3 8.5 0.038 14.2 8.5 1.1 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 CDJ45323.1 - 0.041 12.9 8.3 0.044 12.8 8.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PPP4R2 PF09184.11 CDJ45323.1 - 0.041 13.5 9.6 0.046 13.3 9.6 1.1 1 0 0 1 1 1 0 PPP4R2 CPSF100_C PF13299.6 CDJ45323.1 - 0.053 13.7 7.3 0.064 13.4 7.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Suf PF05843.14 CDJ45323.1 - 0.061 13.3 9.9 0.064 13.2 9.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SpoIIP PF07454.11 CDJ45323.1 - 0.063 12.7 10.2 0.07 12.6 10.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) MIIP PF15734.5 CDJ45323.1 - 0.064 12.7 11.2 0.066 12.7 11.2 1.0 1 0 0 1 1 1 0 Migration and invasion-inhibitory Velvet PF11754.8 CDJ45323.1 - 0.075 13.0 10.2 0.08 12.9 10.2 1.0 1 0 0 1 1 1 0 Velvet factor Serinc PF03348.15 CDJ45323.1 - 0.076 11.9 5.6 0.08 11.9 5.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3682 PF12446.8 CDJ45323.1 - 0.076 13.5 30.1 0.12 12.8 30.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) SAPS PF04499.15 CDJ45323.1 - 0.077 11.8 8.0 0.079 11.7 8.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF5427 PF10310.9 CDJ45323.1 - 0.091 11.7 15.7 0.087 11.8 15.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Rtf2 PF04641.12 CDJ45323.1 - 0.098 12.0 9.2 0.11 11.9 9.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Presenilin PF01080.17 CDJ45323.1 - 0.1 11.3 15.8 0.11 11.3 15.8 1.0 1 0 0 1 1 1 0 Presenilin CBP_BcsG PF11658.8 CDJ45323.1 - 0.13 10.6 4.2 0.14 10.5 4.2 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF4603 PF15376.6 CDJ45323.1 - 0.15 9.4 11.6 0.17 9.3 11.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Peptidase_C37 PF05416.12 CDJ45323.1 - 0.15 10.5 4.9 0.18 10.3 4.9 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase SID-1_RNA_chan PF13965.6 CDJ45323.1 - 0.19 10.1 2.6 0.19 10.1 2.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TFIIA PF03153.13 CDJ45323.1 - 0.21 11.6 22.7 0.24 11.3 22.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ45323.1 - 0.25 11.4 6.2 0.26 11.3 6.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MDM31_MDM32 PF08118.11 CDJ45323.1 - 0.33 9.6 3.8 0.34 9.5 3.8 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins CSG2 PF16965.5 CDJ45323.1 - 0.35 9.8 4.1 0.39 9.6 4.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator BAF1_ABF1 PF04684.13 CDJ45323.1 - 0.43 9.6 15.4 0.52 9.3 15.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CLN3 PF02487.17 CDJ45323.1 - 0.45 9.5 5.1 0.43 9.6 5.1 1.1 1 0 0 1 1 1 0 CLN3 protein DDRGK PF09756.9 CDJ45323.1 - 0.47 10.0 15.5 0.59 9.7 15.5 1.2 1 0 0 1 1 1 0 DDRGK domain PA26 PF04636.13 CDJ45323.1 - 0.47 9.3 8.2 0.48 9.3 8.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Connexin PF00029.19 CDJ45323.1 - 0.48 10.1 6.9 0.55 9.9 6.9 1.1 1 0 0 1 1 1 0 Connexin RXLR PF16810.5 CDJ45323.1 - 0.53 10.7 8.8 0.86 10.0 8.8 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity FancD2 PF14631.6 CDJ45323.1 - 0.54 7.6 6.9 0.51 7.7 6.9 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Folate_carrier PF01770.18 CDJ45323.1 - 0.55 8.9 2.7 0.56 8.9 2.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier GREB1 PF15782.5 CDJ45323.1 - 0.6 7.2 10.7 0.62 7.1 10.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ALMT PF11744.8 CDJ45323.1 - 0.65 8.8 5.9 0.65 8.8 5.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter FHIPEP PF00771.20 CDJ45323.1 - 0.69 8.3 5.4 0.81 8.1 5.4 1.1 1 0 0 1 1 1 0 FHIPEP family R_equi_Vir PF05526.11 CDJ45323.1 - 0.74 9.6 9.8 0.97 9.3 9.8 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein RPN2_C PF18004.1 CDJ45323.1 - 0.76 9.7 13.6 0.97 9.3 13.6 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF5423 PF17461.2 CDJ45323.1 - 0.89 8.3 9.3 1.1 8.0 9.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Plasmodium_Vir PF05795.11 CDJ45323.1 - 0.89 8.9 6.3 0.9 8.9 6.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM60A PF15396.6 CDJ45323.1 - 0.93 9.5 9.4 1.1 9.2 9.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Spt20 PF12090.8 CDJ45323.1 - 0.95 9.0 25.7 1.2 8.8 25.7 1.2 1 0 0 1 1 1 0 Spt20 family DUF4228 PF14009.6 CDJ45323.1 - 1 9.8 10.1 1 9.7 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) TMEM174 PF15029.6 CDJ45323.1 - 1 9.0 7.1 1.3 8.7 7.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 174 HA2 PF04408.23 CDJ45323.1 - 1.1 9.6 6.0 2.2 8.6 6.0 1.6 1 0 0 1 1 1 0 Helicase associated domain (HA2) EOS1 PF12326.8 CDJ45323.1 - 1.2 9.1 4.7 1.3 8.9 4.7 1.2 1 0 0 1 1 1 0 N-glycosylation protein Zip PF02535.22 CDJ45323.1 - 1.6 7.9 8.7 2 7.6 8.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MAJIN PF15077.6 CDJ45323.1 - 1.7 8.4 9.3 2.1 8.1 9.3 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Usp PF00582.26 CDJ45323.1 - 1.8 9.1 7.8 3 8.3 7.8 1.4 1 0 0 1 1 1 0 Universal stress protein family Paramyxo_ncap PF00973.19 CDJ45323.1 - 1.9 7.3 6.8 2 7.2 6.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1980 PF09323.10 CDJ45323.1 - 2 8.3 7.7 2.4 8.1 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SLC12 PF03522.15 CDJ45323.1 - 2.1 7.3 10.6 2.4 7.1 10.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FAM176 PF14851.6 CDJ45323.1 - 2.1 8.0 10.5 2.9 7.6 10.5 1.3 1 0 0 1 1 1 0 FAM176 family TFB6 PF17110.5 CDJ45323.1 - 2.2 8.0 8.5 2.6 7.7 8.5 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH XRN_M PF17846.1 CDJ45323.1 - 2.3 7.1 9.5 2.5 7.0 9.5 1.0 1 0 0 1 1 1 0 Xrn1 helical domain DUF3408 PF11888.8 CDJ45323.1 - 2.6 8.2 14.3 3.3 7.9 14.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) CDC45 PF02724.14 CDJ45323.1 - 3.1 6.0 13.7 3.3 5.9 13.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Mlh1_C PF16413.5 CDJ45323.1 - 3.3 7.0 10.9 5.2 6.4 10.9 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus RR_TM4-6 PF06459.12 CDJ45323.1 - 3.4 7.4 17.8 4.1 7.1 17.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AIF_C PF14721.6 CDJ45323.1 - 3.7 7.9 12.2 5.3 7.4 12.2 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PPL5 PF18168.1 CDJ45323.1 - 3.8 6.7 9.1 4.7 6.4 9.1 1.1 1 0 0 1 1 1 0 Prim-pol family 5 TERB2 PF15101.6 CDJ45323.1 - 4.2 7.4 15.8 5.2 7.1 15.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4746 PF15928.5 CDJ45323.1 - 4.5 6.6 14.1 5.2 6.4 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TRAP_alpha PF03896.16 CDJ45323.1 - 4.7 6.3 11.0 5.7 6.0 11.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NPR3 PF03666.13 CDJ45323.1 - 5.6 5.6 15.7 6.5 5.4 15.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3537 PF12056.8 CDJ45323.1 - 5.7 5.6 8.1 6.2 5.5 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) O-antigen_lig PF13425.6 CDJ45323.1 - 5.8 5.6 4.5 6.2 5.5 4.5 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Paf1 PF03985.13 CDJ45323.1 - 6.2 5.7 18.9 6.6 5.6 18.9 1.1 1 0 0 1 1 1 0 Paf1 eIF3_subunit PF08597.10 CDJ45323.1 - 6.6 6.6 21.9 8.3 6.2 21.9 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CobT PF06213.12 CDJ45323.1 - 7.3 5.9 26.3 9.9 5.5 26.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pex14_N PF04695.13 CDJ45323.1 - 7.4 7.2 21.2 9.8 6.8 21.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bul1_N PF04425.12 CDJ45323.1 - 9.5 4.9 12.5 11 4.6 12.5 1.0 1 0 0 1 1 1 0 Bul1 N terminus Ank_2 PF12796.7 CDJ45324.1 - 2.4e-05 24.8 0.0 0.00011 22.7 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ45324.1 - 0.0014 19.1 0.6 1.7 9.3 0.0 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 CDJ45325.1 - 0.0036 17.7 0.1 0.0036 17.7 0.1 3.4 1 1 1 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.17 CDJ45325.1 - 0.0036 17.0 0.0 0.0087 15.8 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 CDJ45325.1 - 0.0059 17.0 0.0 0.02 15.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CDJ45325.1 - 0.0084 16.5 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 CDJ45325.1 - 0.014 15.7 2.0 0.046 14.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDJ45325.1 - 0.024 14.1 0.2 0.024 14.1 0.2 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region ResIII PF04851.15 CDJ45325.1 - 0.033 14.2 0.0 0.033 14.2 0.0 2.3 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit AFG1_ATPase PF03969.16 CDJ45325.1 - 0.037 12.9 0.0 0.037 12.9 0.0 2.7 2 1 1 3 3 2 0 AFG1-like ATPase Hpr_kinase_C PF07475.12 CDJ45325.1 - 0.042 13.4 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_5 PF07728.14 CDJ45325.1 - 0.057 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CDJ45325.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_33 PF13671.6 CDJ45325.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.7 2 1 0 2 2 1 0 AAA domain AAA_24 PF13479.6 CDJ45325.1 - 0.2 11.4 0.7 0.85 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Bac_transf PF02397.16 CDJ45325.1 - 0.88 9.1 2.5 1.5 8.4 2.5 1.3 1 0 0 1 1 1 0 Bacterial sugar transferase DUF1744 PF08490.12 CDJ45325.1 - 3 6.3 7.3 6.5 5.2 7.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) WD40 PF00400.32 CDJ45326.1 - 1.6e-31 107.8 21.6 4.5e-08 33.6 0.3 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ45326.1 - 5.2e-12 45.9 7.6 0.06 13.6 0.1 4.9 4 1 1 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CDJ45326.1 - 0.00027 20.1 0.6 0.24 10.4 0.1 2.8 3 0 0 3 3 3 2 Coatomer WD associated region Nucleoporin_N PF08801.11 CDJ45326.1 - 0.0068 15.2 0.1 12 4.4 0.0 3.0 3 0 0 3 3 3 1 Nup133 N terminal like Nbas_N PF15492.6 CDJ45326.1 - 0.049 13.0 0.5 0.049 13.0 0.5 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DUF866 PF05907.13 CDJ45326.1 - 0.062 13.2 1.5 0.16 11.8 0.4 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) Ge1_WD40 PF16529.5 CDJ45326.1 - 0.063 12.2 5.0 6.1 5.7 0.1 3.5 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3357 PF11837.8 CDJ45326.1 - 0.073 13.5 4.0 0.11 12.9 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Presenilin PF01080.17 CDJ45326.1 - 0.21 10.3 4.5 0.13 11.0 1.6 1.8 2 0 0 2 2 2 0 Presenilin DUF2722 PF10846.8 CDJ45326.1 - 0.4 9.6 24.2 2.4 7.0 2.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) FAM176 PF14851.6 CDJ45326.1 - 1.1 8.9 3.8 8.5 6.0 0.2 2.8 3 0 0 3 3 3 0 FAM176 family RAB3GAP2_N PF14655.6 CDJ45326.1 - 2.5 7.3 19.5 2.2 7.5 0.3 3.5 3 1 1 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.8 CDJ45326.1 - 3.3 7.2 37.4 0.9 9.1 4.4 3.1 3 0 0 3 3 3 0 Spt20 family Retrotrans_gag PF03732.17 CDJ45327.1 - 0.00038 20.7 1.0 0.0014 18.9 0.1 2.2 3 0 0 3 3 3 1 Retrotransposon gag protein Lipase_3 PF01764.25 CDJ45328.1 - 4.9e-13 49.2 0.0 1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Voldacs PF03517.13 CDJ45329.1 - 6.5e-25 87.9 0.0 1.1e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling BBL5 PF07289.11 CDJ45329.1 - 0.088 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein RMI1_N PF08585.12 CDJ45330.1 - 2.2e-14 53.7 0.8 4e-13 49.6 0.0 2.7 2 1 0 2 2 2 1 RecQ mediated genome instability protein Coatomer_WDAD PF04053.14 CDJ45331.1 - 1.3e-05 24.5 0.6 0.0031 16.6 0.5 3.2 4 0 0 4 4 4 2 Coatomer WD associated region Nucleoporin_N PF08801.11 CDJ45331.1 - 0.037 12.8 0.0 0.064 12.0 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like PD40 PF07676.12 CDJ45331.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat TPR_2 PF07719.17 CDJ45331.1 - 1.4 9.2 13.7 11 6.4 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat ubiquitin PF00240.23 CDJ45332.1 - 0.0042 16.8 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF4131 PF13567.6 CDJ45332.1 - 0.1 12.2 2.2 0.22 11.2 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2407 PF10302.9 CDJ45332.1 - 0.14 12.7 0.0 0.21 12.2 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PPR_2 PF13041.6 CDJ45334.1 - 0.0031 17.7 0.0 0.38 11.0 0.0 3.4 3 0 0 3 3 3 1 PPR repeat family SET PF00856.28 CDJ45336.1 - 7e-08 33.0 0.1 2e-06 28.3 0.0 2.7 2 1 0 2 2 2 1 SET domain ADK PF00406.22 CDJ45337.1 - 7.5e-27 94.3 0.0 9.5e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDJ45337.1 - 5.6e-15 56.0 0.0 1.1e-14 55.0 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDJ45337.1 - 0.00013 22.6 0.0 0.00025 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CDJ45337.1 - 0.0042 17.0 4.3 0.0093 15.9 4.3 1.6 1 1 0 1 1 1 1 Adenylate kinase, active site lid NACHT PF05729.12 CDJ45337.1 - 0.0053 16.7 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 CDJ45337.1 - 0.0069 16.6 0.0 0.011 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CDJ45337.1 - 0.012 16.1 0.0 0.069 13.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 CDJ45337.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase Rad17 PF03215.15 CDJ45337.1 - 0.037 14.0 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain SKI PF01202.22 CDJ45337.1 - 0.057 13.6 0.0 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Shikimate kinase Peptidase_U4 PF03419.13 CDJ45339.1 - 0.0051 16.1 1.6 0.0085 15.4 1.6 1.2 1 0 0 1 1 1 1 Sporulation factor SpoIIGA PDEase_I PF00233.19 CDJ45340.1 - 1.8e-44 152.2 0.1 2.3e-44 151.9 0.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase EIAV_GP90 PF00971.18 CDJ45340.1 - 0.069 11.8 0.0 0.097 11.3 0.0 1.2 1 0 0 1 1 1 0 EIAV coat protein, gp90 PDEase_I PF00233.19 CDJ45341.1 - 1.1e-08 35.2 0.0 1.6e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase STOP PF05217.12 CDJ45342.1 - 7.2e-06 26.2 4.6 0.0011 19.2 0.8 5.0 6 0 0 6 6 6 1 STOP protein zf-RING_2 PF13639.6 CDJ45343.1 - 1.1e-11 44.8 7.6 1.1e-11 44.8 7.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CDJ45343.1 - 4.2e-09 36.0 7.0 1.2e-08 34.6 7.0 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 CDJ45343.1 - 3e-08 33.8 6.0 8.9e-08 32.3 6.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CDJ45343.1 - 6.9e-06 25.8 6.6 6.9e-06 25.8 6.6 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ45343.1 - 2.9e-05 23.8 7.0 6.2e-05 22.8 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ45343.1 - 5.5e-05 23.1 5.9 0.00014 21.8 5.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ45343.1 - 6.6e-05 22.8 5.8 0.00015 21.7 5.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDJ45343.1 - 0.0003 20.6 5.9 0.00068 19.4 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CDJ45343.1 - 0.0014 18.2 3.9 0.0014 18.2 3.9 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CDJ45343.1 - 0.0019 18.0 6.8 0.0044 16.8 6.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 CDJ45343.1 - 0.015 15.2 6.9 0.023 14.6 2.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 CDJ45343.1 - 0.034 13.9 5.7 0.092 12.5 5.7 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 CDJ45343.1 - 0.062 13.4 6.2 0.27 11.3 6.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CDJ45343.1 - 1.4 9.1 9.1 36 4.6 9.1 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain Aconitase PF00330.20 CDJ45344.1 - 7.3e-184 612.1 0.0 9.7e-184 611.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CDJ45344.1 - 7e-41 139.6 0.0 1.2e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Rtf2 PF04641.12 CDJ45345.1 - 1.1e-43 149.5 0.1 2.6e-43 148.3 0.1 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 CDJ45345.1 - 0.045 13.6 1.2 6.3 6.7 0.2 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 DUF2842 PF11003.8 CDJ45346.1 - 0.055 13.7 1.7 0.086 13.1 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) Popeye PF04831.13 CDJ45346.1 - 0.15 12.3 4.0 0.2 11.9 4.0 1.2 1 0 0 1 1 1 0 Popeye protein conserved region Cofilin_ADF PF00241.20 CDJ45347.1 - 8.4e-27 93.4 0.0 1.1e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein EnY2 PF10163.9 CDJ45348.1 - 4.4e-08 33.4 0.5 7.4e-08 32.7 0.5 1.3 1 0 0 1 1 1 1 Transcription factor e(y)2 tRNA-synt_2b PF00587.25 CDJ45349.1 - 5e-31 108.1 0.0 3.7e-29 101.9 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CDJ45349.1 - 1.5e-21 76.3 0.1 3.9e-21 75.0 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 CDJ45349.1 - 1.1e-10 41.5 0.0 2.6e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 CDJ45349.1 - 6.9e-08 32.4 0.0 1e-06 28.7 0.0 2.8 2 1 0 2 2 2 1 TGS domain Hydrolase PF00702.26 CDJ45349.1 - 0.023 15.0 0.1 0.052 13.8 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PhoLip_ATPase_C PF16212.5 CDJ45351.1 - 9.7e-45 153.3 22.2 9.7e-45 153.3 22.2 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDJ45351.1 - 2.7e-15 55.8 5.8 2.7e-15 55.8 5.8 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CDJ45351.1 - 2e-13 51.1 0.3 1e-06 29.2 0.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ45351.1 - 5.2e-10 39.3 0.0 3.2e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CDJ45351.1 - 0.0039 16.7 19.1 0.011 15.2 0.0 4.9 5 0 0 5 5 5 2 E1-E2 ATPase Hydrolase_3 PF08282.12 CDJ45351.1 - 0.0088 15.8 0.1 0.023 14.5 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AP2 PF00847.20 CDJ45352.1 - 0.00078 19.6 0.0 2.2 8.6 0.0 2.6 2 0 0 2 2 2 2 AP2 domain zf-His_Me_endon PF05551.11 CDJ45353.1 - 0.043 14.0 0.0 0.067 13.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease SUI1 PF01253.22 CDJ45354.1 - 2.1e-16 60.2 0.0 4.1e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Aldo_ket_red PF00248.21 CDJ45355.1 - 1.3e-35 123.1 0.0 1.1e-33 116.7 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family TraG_N PF07916.11 CDJ45356.1 - 1.5 7.6 11.2 3.3 6.5 11.2 1.5 1 0 0 1 1 1 0 TraG-like protein, N-terminal region RCC1 PF00415.18 CDJ45357.1 - 6.1e-19 68.4 0.5 2.3e-06 28.1 0.2 4.3 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ45357.1 - 1.4e-13 50.2 14.4 8.7e-09 35.0 1.4 3.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CDJ45358.1 - 3.4e-13 50.0 1.1 0.0011 19.5 0.0 4.6 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ45358.1 - 0.14 12.0 9.2 9.2 6.2 0.0 4.5 5 0 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat PIG-P PF08510.12 CDJ45359.1 - 5.8e-30 103.7 0.0 7.5e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 CDJ45359.1 - 0.065 13.6 9.8 0.26 11.6 9.8 1.9 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Vma12 PF11712.8 CDJ45359.1 - 0.18 11.9 0.5 0.47 10.5 0.0 1.9 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cytochrome-c551 PF10643.9 CDJ45359.1 - 0.67 9.5 1.7 0.86 9.1 1.7 1.3 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 TPR_1 PF00515.28 CDJ45360.1 - 7.2e-07 28.8 1.4 0.022 14.6 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ45360.1 - 3.3e-06 27.5 1.4 3.3e-06 27.5 1.4 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ45360.1 - 2.4e-05 24.1 13.9 0.011 15.8 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ45360.1 - 0.0014 18.7 2.0 0.0016 18.5 0.2 2.0 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CDJ45360.1 - 0.0015 18.7 1.3 0.0054 16.9 1.3 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CDJ45360.1 - 0.0044 17.3 0.2 0.1 13.0 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ45360.1 - 0.016 15.2 0.6 2.7 8.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4028 PF13220.6 CDJ45360.1 - 0.076 12.8 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) TPR_14 PF13428.6 CDJ45360.1 - 0.11 13.4 0.6 0.11 13.4 0.6 4.8 3 2 2 5 5 5 0 Tetratricopeptide repeat Ribosomal_L2_C PF03947.18 CDJ45361.1 - 6.3e-44 149.2 2.8 3.1e-43 147.0 3.1 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CDJ45361.1 - 2.1e-18 66.1 0.2 4.9e-18 64.9 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Myosin_N PF02736.19 CDJ45361.1 - 2.7 7.9 4.7 11 5.9 0.0 3.0 3 1 1 4 4 4 0 Myosin N-terminal SH3-like domain Mpp10 PF04006.12 CDJ45365.1 - 8.8 4.6 8.7 7.9 4.8 8.7 1.0 1 0 0 1 1 1 0 Mpp10 protein TFIIA PF03153.13 CDJ45367.1 - 0.00047 20.3 55.8 0.027 14.5 22.9 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF1086 PF06461.11 CDJ45367.1 - 0.015 15.1 0.1 0.061 13.2 0.1 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) SpoIIIAH PF12685.7 CDJ45367.1 - 0.042 13.7 27.1 0.09 12.6 7.2 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein MAP7 PF05672.11 CDJ45367.1 - 0.052 13.2 51.2 0.53 10.0 19.2 2.5 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Cwf_Cwc_15 PF04889.12 CDJ45367.1 - 0.23 11.2 32.9 0.79 9.4 10.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein UPF0565 PF10561.9 CDJ45367.1 - 0.29 10.3 8.2 1.2 8.3 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 EPL1 PF10513.9 CDJ45367.1 - 0.32 11.4 27.5 0.63 10.4 7.5 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like Peptidase_S64 PF08192.11 CDJ45367.1 - 0.52 8.7 22.4 1 7.8 8.2 2.1 2 0 0 2 2 2 0 Peptidase family S64 PAT1 PF09770.9 CDJ45367.1 - 1 7.6 41.9 0.86 7.8 18.5 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF572 PF04502.13 CDJ45367.1 - 2.7 7.5 29.7 3.9 7.0 12.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) SRP-alpha_N PF04086.13 CDJ45367.1 - 2.8 7.8 34.6 4.1 7.2 12.5 2.5 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal CobT PF06213.12 CDJ45367.1 - 3 7.1 51.8 1.1 8.6 20.1 2.9 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 CDJ45367.1 - 4 5.6 28.1 1.7 6.8 10.4 2.1 2 0 0 2 2 2 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 CDJ45367.1 - 6 7.3 30.2 13 6.2 11.7 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 Hamartin PF04388.12 CDJ45367.1 - 6.6 5.3 38.4 11 4.5 38.4 1.3 1 0 0 1 1 1 0 Hamartin protein DUF3807 PF12720.7 CDJ45367.1 - 9.7 6.4 45.2 6.4 7.0 13.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) PqqD PF05402.12 CDJ45370.1 - 0.17 12.2 1.0 0.65 10.3 0.4 2.3 1 1 1 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) ATG16 PF08614.11 CDJ45371.1 - 0.017 15.4 30.2 0.033 14.4 30.2 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) SR-25 PF10500.9 CDJ45371.1 - 0.024 14.3 17.3 0.082 12.5 17.1 1.9 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein GAS PF13851.6 CDJ45371.1 - 2.1 7.6 25.7 0.082 12.2 19.8 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 CDJ45371.1 - 3.4 6.2 12.8 4.3 5.8 12.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF421 PF04239.12 CDJ45371.1 - 5.3 6.9 8.1 23 4.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF421) Metal_resist PF13801.6 CDJ45371.1 - 5.5 7.2 26.1 1.3 9.2 21.6 1.9 2 0 0 2 2 2 0 Heavy-metal resistance Utp12 PF04003.12 CDJ45371.1 - 7.1 7.0 12.3 0.77 10.1 4.3 2.5 1 1 1 2 2 2 0 Dip2/Utp12 Family TFIIA PF03153.13 CDJ45372.1 - 0.25 11.3 2.9 0.23 11.4 2.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TB PF00683.17 CDJ45372.1 - 6.2 6.6 14.0 2.2 8.1 4.9 2.3 2 0 0 2 2 2 0 TB domain Utp14 PF04615.13 CDJ45373.1 - 3.6 6.0 8.2 4.9 5.6 8.2 1.1 1 0 0 1 1 1 0 Utp14 protein CIAPIN1 PF05093.13 CDJ45374.1 - 1.7e-20 73.4 14.4 5.9e-18 65.2 14.4 2.5 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis OxoDH_E1alpha_N PF12573.8 CDJ45374.1 - 0.16 11.7 0.6 1.3 8.8 0.3 2.6 2 1 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal DUF3716 PF12511.8 CDJ45374.1 - 5.9 7.0 11.7 15 5.7 2.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3716) Pkinase PF00069.25 CDJ45375.1 - 5.9e-26 91.4 0.0 1.1e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 CDJ45375.1 - 2.6e-24 82.9 2.1 8.6e-06 25.0 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDJ45375.1 - 3.2e-20 70.3 2.1 6.8e-06 25.6 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 CDJ45375.1 - 6e-20 71.5 5.1 1e-11 45.1 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ45375.1 - 5e-18 63.7 6.3 1.3e-06 27.6 0.2 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 CDJ45375.1 - 8.6e-12 44.7 3.8 0.0033 17.2 0.1 3.7 4 0 0 4 4 4 3 EF-hand domain pair Pkinase_Tyr PF07714.17 CDJ45375.1 - 8.3e-10 38.4 0.1 1.1e-08 34.7 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase SPARC_Ca_bdg PF10591.9 CDJ45375.1 - 2.9e-06 27.6 1.8 0.057 13.7 0.2 3.2 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 CDJ45375.1 - 0.0036 16.7 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like EF-hand_10 PF14788.6 CDJ45375.1 - 0.028 14.3 0.8 1.9 8.4 0.0 3.6 4 0 0 4 4 4 0 EF hand RNA_pol_L_2 PF13656.6 CDJ45376.1 - 2.9e-13 49.4 0.0 4.2e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Anillin PF08174.11 CDJ45376.1 - 0.065 13.7 0.1 0.36 11.2 0.2 1.9 2 0 0 2 2 2 0 Cell division protein anillin RRM_1 PF00076.22 CDJ45377.1 - 3.4e-21 74.8 0.0 2e-19 69.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ45377.1 - 0.0071 16.5 0.0 0.03 14.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ45377.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Peptidase_A21 PF03566.13 CDJ45377.1 - 0.28 9.4 2.7 0.43 8.8 2.7 1.2 1 0 0 1 1 1 0 Peptidase family A21 AAA PF00004.29 CDJ45382.1 - 5.7e-43 146.5 0.0 8.6e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ45382.1 - 1.1e-11 44.4 0.2 3e-11 42.9 0.2 1.9 1 1 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 CDJ45382.1 - 2.8e-07 30.8 0.0 5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ45382.1 - 5.9e-07 30.0 1.6 2.3e-06 28.1 1.6 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CDJ45382.1 - 1.4e-06 28.4 0.3 8.5e-06 25.8 0.2 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 CDJ45382.1 - 1.7e-06 28.0 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein RuvB_N PF05496.12 CDJ45382.1 - 2.2e-06 27.5 0.0 5.3e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CDJ45382.1 - 0.0002 21.4 0.0 0.00031 20.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CDJ45382.1 - 0.00029 20.2 0.1 0.0012 18.2 0.1 1.8 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 CDJ45382.1 - 0.00042 20.6 1.0 0.075 13.3 0.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 CDJ45382.1 - 0.00044 20.4 0.0 0.00091 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 CDJ45382.1 - 0.0012 19.1 0.2 0.0064 16.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CDJ45382.1 - 0.0025 17.6 0.5 0.031 14.0 0.5 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain NACHT PF05729.12 CDJ45382.1 - 0.0036 17.2 0.4 0.094 12.6 0.2 2.2 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 CDJ45382.1 - 0.0094 15.7 0.5 0.053 13.3 0.1 2.3 2 1 1 3 3 3 1 IstB-like ATP binding protein TsaE PF02367.17 CDJ45382.1 - 0.02 14.9 0.0 0.053 13.5 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CDJ45382.1 - 0.036 14.6 0.0 0.064 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDJ45382.1 - 0.051 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CPT PF07931.12 CDJ45382.1 - 0.057 13.3 0.2 0.57 10.0 0.0 2.4 2 1 1 3 3 3 0 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 CDJ45382.1 - 0.067 12.5 0.1 0.31 10.4 0.1 2.1 1 1 0 1 1 1 0 KaiC Zeta_toxin PF06414.12 CDJ45382.1 - 0.11 11.8 0.1 0.24 10.6 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 CDJ45382.1 - 0.11 12.0 0.1 0.3 10.6 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 CDJ45382.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 CDJ45382.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 CDJ45382.1 - 0.13 12.7 0.0 0.32 11.5 0.0 1.9 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 CDJ45382.1 - 0.15 11.6 3.5 7.2 6.1 0.7 2.6 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 CDJ45382.1 - 0.15 11.2 0.1 0.35 10.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 CDJ45382.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CDJ45382.1 - 0.2 10.9 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) APG6_N PF17675.1 CDJ45383.1 - 0.0019 18.7 6.1 0.002 18.6 6.1 1.0 1 0 0 1 1 1 1 Apg6 coiled-coil region JIP_LZII PF16471.5 CDJ45383.1 - 0.013 15.6 5.8 0.015 15.4 5.8 1.1 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Form_Nir_trans PF01226.17 CDJ45384.1 - 7.1e-48 163.0 3.5 8.8e-48 162.7 3.5 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter TrbC PF04956.13 CDJ45384.1 - 0.003 17.8 1.8 0.0064 16.7 1.8 1.5 1 0 0 1 1 1 1 TrbC/VIRB2 family Spore_permease PF03845.13 CDJ45384.1 - 0.059 12.2 4.2 0.083 11.7 4.2 1.2 1 0 0 1 1 1 0 Spore germination protein PIG-F PF06699.11 CDJ45384.1 - 4.8 7.3 7.6 4.7 7.3 2.2 2.2 1 1 1 2 2 2 0 GPI biosynthesis protein family Pig-F Ctr PF04145.15 CDJ45385.1 - 1.9e-09 38.3 17.7 9.7e-09 36.0 14.2 3.4 2 1 0 2 2 2 1 Ctr copper transporter family DUF1180 PF06679.12 CDJ45386.1 - 0.047 14.1 15.0 15 6.0 15.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) RAP1 PF07218.11 CDJ45386.1 - 1.2 7.3 3.7 1.2 7.3 3.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2722 PF10846.8 CDJ45388.1 - 0.0079 15.2 0.4 0.0079 15.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) SARAF PF06682.12 CDJ45388.1 - 0.0094 15.6 2.0 0.011 15.4 2.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Spt20 PF12090.8 CDJ45388.1 - 0.065 12.8 8.6 0.1 12.2 8.6 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ45388.1 - 0.58 10.3 14.2 0.15 12.2 8.5 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ45389.1 - 0.011 15.7 2.1 0.015 15.3 2.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAB3GAP2_N PF14655.6 CDJ45389.1 - 0.092 12.0 0.4 0.16 11.2 0.4 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Roughex PF06020.11 CDJ45389.1 - 0.13 11.3 1.6 0.22 10.6 1.6 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DUF3138 PF11336.8 CDJ45389.1 - 0.48 9.0 4.1 0.59 8.7 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Methyltr_RsmB-F PF01189.17 CDJ45390.1 - 9.7e-05 22.1 1.2 0.053 13.2 0.2 2.3 1 1 1 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 CDJ45390.1 - 0.0023 18.6 0.1 0.075 13.7 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 CDJ45390.1 - 0.068 13.3 0.1 0.2 11.7 0.1 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 CDJ45390.1 - 0.08 12.7 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain SPX PF03105.19 CDJ45390.1 - 0.6 10.0 10.4 1 9.2 3.7 2.1 2 0 0 2 2 2 0 SPX domain AP2 PF00847.20 CDJ45393.1 - 7.8e-10 38.8 21.6 1.6e-07 31.5 5.4 6.3 6 1 1 7 7 7 4 AP2 domain ACDC PF14733.6 CDJ45393.1 - 2.9e-05 24.3 0.5 8.9e-05 22.7 0.5 1.9 1 0 0 1 1 1 1 AP2-coincident C-terminal DUF3791 PF12668.7 CDJ45393.1 - 0.26 11.3 0.1 24 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) WD40 PF00400.32 CDJ45394.1 - 1.1e-06 29.3 11.8 0.0082 17.0 0.2 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ45394.1 - 0.008 16.5 0.0 63 4.0 0.0 4.7 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain SUIM_assoc PF16619.5 CDJ45394.1 - 0.4 10.8 40.3 0.061 13.4 5.8 4.4 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 RNA_pol_Rpb5_N PF03871.14 CDJ45395.1 - 1.2e-21 77.1 0.0 1.3e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Amino_oxidase PF01593.24 CDJ45398.1 - 3.2e-15 56.4 4.9 1e-07 31.6 0.1 3.2 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ45398.1 - 2.2e-09 37.4 0.8 2.4e-08 34.1 0.9 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ45398.1 - 1e-05 25.0 1.1 2.2e-05 23.9 1.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ45398.1 - 0.00021 21.8 1.2 0.00044 20.8 1.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ45398.1 - 0.00049 18.9 1.7 0.00091 18.0 1.7 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 CDJ45398.1 - 0.002 17.4 0.1 0.0038 16.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ45398.1 - 0.11 11.7 2.3 0.22 10.8 2.3 1.3 1 0 0 1 1 1 0 Thi4 family Zip PF02535.22 CDJ45398.1 - 1.4 8.0 4.5 5.2 6.2 0.7 2.7 2 0 0 2 2 2 0 ZIP Zinc transporter Torus PF16131.5 CDJ45399.1 - 1.3e-07 32.3 18.4 4.3e-05 24.2 0.6 3.2 1 1 2 3 3 3 2 Torus domain zf-CCCH PF00642.24 CDJ45399.1 - 0.0025 17.7 10.6 0.011 15.6 0.3 2.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ45399.1 - 0.0038 17.0 1.7 0.0038 17.0 1.7 3.5 4 0 0 4 4 4 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CDJ45399.1 - 0.0039 17.4 11.8 0.038 14.2 0.3 2.8 2 1 0 2 2 2 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 CDJ45399.1 - 0.014 15.4 4.4 0.014 15.4 4.4 3.2 3 0 0 3 3 3 0 Zinc finger domain RskA PF10099.9 CDJ45399.1 - 1.1 9.5 12.3 0.066 13.5 7.4 1.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ45399.1 - 1.1 9.4 13.7 3.8 7.6 2.5 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 CDJ45399.1 - 2.3 7.3 11.5 0.68 9.1 4.8 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal ATP12 PF07542.11 CDJ45400.1 - 0.00052 20.1 7.9 0.00052 20.1 7.9 2.9 2 1 0 2 2 2 1 ATP12 chaperone protein Spt20 PF12090.8 CDJ45400.1 - 2.6 7.6 31.8 0.61 9.7 14.9 2.4 2 0 0 2 2 2 0 Spt20 family HAGH_C PF16123.5 CDJ45400.1 - 7.6 7.1 6.1 2.2 8.9 1.1 2.5 2 0 0 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus F-box-like PF12937.7 CDJ45403.1 - 0.0055 16.6 2.4 0.022 14.6 2.4 2.1 1 0 0 1 1 1 1 F-box-like DUF4200 PF13863.6 CDJ45404.1 - 2.2e-13 50.6 23.8 3.1e-13 50.2 23.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) HEPN_Toprim_N PF18871.1 CDJ45404.1 - 0.007 16.3 1.8 0.009 16.0 1.8 1.1 1 0 0 1 1 1 1 HEPN/Toprim N-terminal domain 1 Cob_adeno_trans PF01923.18 CDJ45404.1 - 0.017 15.3 3.6 0.024 14.8 3.6 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Sororin PF09666.10 CDJ45404.1 - 0.061 13.5 4.5 0.086 13.1 4.5 1.3 1 0 0 1 1 1 0 Sororin protein Fungal_trans_2 PF11951.8 CDJ45404.1 - 0.32 9.8 9.4 0.81 8.4 6.5 1.9 1 1 1 2 2 2 0 Fungal specific transcription factor domain Exonuc_VII_L PF02601.15 CDJ45404.1 - 0.51 9.9 13.0 0.57 9.7 13.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 CDJ45404.1 - 0.79 9.0 11.0 1.1 8.6 11.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec2p PF06428.11 CDJ45404.1 - 1.9 8.5 24.3 1.7 8.7 9.7 2.7 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p FapA PF03961.13 CDJ45404.1 - 4.9 5.6 9.3 6 5.4 9.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A RIIa PF02197.17 CDJ45405.1 - 0.00017 21.1 1.8 0.00017 21.1 1.8 1.8 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit Spt20 PF12090.8 CDJ45405.1 - 0.0014 18.3 8.1 0.0016 18.1 8.1 1.2 1 0 0 1 1 1 1 Spt20 family Dpy-30 PF05186.13 CDJ45405.1 - 0.0098 15.6 0.9 0.024 14.4 0.9 1.7 1 0 0 1 1 1 1 Dpy-30 motif Hydin_ADK PF17213.3 CDJ45405.1 - 0.012 15.9 1.7 2.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain T2SSF PF00482.23 CDJ45405.1 - 0.015 15.3 0.7 0.042 13.8 0.7 1.8 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Peroxin-13_N PF04088.13 CDJ45405.1 - 0.017 15.4 0.1 0.026 14.8 0.1 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF2232 PF09991.9 CDJ45405.1 - 0.02 14.1 0.4 0.022 13.9 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) MID_MedPIWI PF18296.1 CDJ45405.1 - 0.031 14.0 3.9 0.14 11.9 4.0 1.8 2 0 0 2 2 2 0 MID domain of medPIWI DUF2722 PF10846.8 CDJ45405.1 - 0.037 13.0 7.6 0.039 12.9 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Ytp1 PF10355.9 CDJ45405.1 - 0.054 12.7 0.3 0.071 12.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) DUF5586 PF17824.1 CDJ45405.1 - 0.097 11.8 4.1 0.13 11.3 4.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5586) Mad3_BUB1_I PF08311.12 CDJ45405.1 - 0.11 12.5 5.1 0.17 11.9 4.8 1.6 1 1 0 1 1 1 0 Mad3/BUB1 homology region 1 Pyrid_oxidase_2 PF13883.6 CDJ45405.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase AAA_33 PF13671.6 CDJ45405.1 - 0.15 12.3 4.4 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Androgen_recep PF02166.16 CDJ45405.1 - 0.18 10.6 8.9 0.19 10.5 8.9 1.3 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 CDJ45405.1 - 0.47 10.4 11.9 0.47 10.4 11.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit U1snRNP70_N PF12220.8 CDJ45405.1 - 1.1 10.0 9.9 0.31 11.7 6.1 2.0 2 1 0 2 2 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal T2SSE PF00437.20 CDJ45406.1 - 0.00014 21.0 5.7 0.00051 19.2 5.6 2.0 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CDJ45406.1 - 0.022 15.1 0.6 0.022 15.1 0.6 2.7 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDJ45406.1 - 0.05 13.9 0.1 0.05 13.9 0.1 3.8 1 1 1 3 3 3 0 AAA domain ResIII PF04851.15 CDJ45406.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 CDJ45406.1 - 0.23 11.6 0.1 0.23 11.6 0.1 4.7 2 1 1 4 4 4 0 AAA domain AAA_14 PF13173.6 CDJ45406.1 - 0.55 10.3 0.0 0.55 10.3 0.0 2.8 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 CDJ45406.1 - 0.9 10.0 0.0 0.9 10.0 0.0 3.6 2 1 0 2 2 2 0 ABC transporter Glyco_hydro_38 PF18438.1 CDJ45406.1 - 2.8 8.0 10.2 0.25 11.4 0.3 3.3 2 1 1 3 3 3 0 Glycosyl hydrolases family 38 C-terminal domain 1 ACDC PF14733.6 CDJ45407.1 - 2.1e-15 56.8 6.1 2.1e-15 56.8 6.1 2.2 2 0 0 2 2 2 1 AP2-coincident C-terminal WD40 PF00400.32 CDJ45408.1 - 0.00086 20.1 5.8 1.1 10.3 0.3 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Caa3_CtaG PF09678.10 CDJ45409.1 - 0.088 12.2 7.3 0.12 11.8 7.3 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Tic110 PF16940.5 CDJ45409.1 - 1.4 7.3 10.7 1.8 7.0 10.7 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter Sporozoite_P67 PF05642.11 CDJ45409.1 - 7 4.6 8.9 9.3 4.2 8.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SR-25 PF10500.9 CDJ45411.1 - 0.0072 16.0 5.2 0.014 15.0 5.2 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ45411.1 - 0.34 9.0 17.0 0.046 11.8 13.0 1.4 1 1 0 1 1 1 0 AF-4 proto-oncoprotein DUF4429 PF14472.6 CDJ45411.1 - 1.1 9.9 4.0 7.2 7.3 0.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4429) XPA_C PF05181.12 CDJ45413.1 - 0.00057 19.8 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 XPA protein C-terminus Neugrin PF06413.11 CDJ45413.1 - 0.1 12.6 6.2 0.23 11.4 6.2 1.5 1 0 0 1 1 1 0 Neugrin FemAB PF02388.16 CDJ45414.1 - 0.11 11.4 2.3 0.12 11.2 2.3 1.0 1 0 0 1 1 1 0 FemAB family DUF1645 PF07816.11 CDJ45415.1 - 6.4 7.3 24.3 0.058 14.0 8.8 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1645) VPS13_C PF16909.5 CDJ45416.1 - 1.6e-07 31.3 0.1 4.6e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Neur_chan_memb PF02932.16 CDJ45416.1 - 0.26 11.3 1.6 0.66 10.0 0.3 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Rad54_N PF08658.10 CDJ45416.1 - 0.32 11.1 4.0 0.58 10.3 4.0 1.3 1 0 0 1 1 1 0 Rad54 N terminal EFTUD2 PF16004.5 CDJ45416.1 - 1.1 9.9 5.4 2.6 8.7 5.4 1.5 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Actin PF00022.19 CDJ45417.1 - 3.1e-40 138.1 0.0 3.4e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Actin WD40 PF00400.32 CDJ45418.1 - 6.4e-16 58.5 3.7 1.8e-06 28.6 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ45418.1 - 1.5e-10 41.2 0.0 0.001 19.4 0.1 3.2 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ45418.1 - 0.0029 16.6 3.6 0.77 8.7 0.2 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ45418.1 - 0.01 14.5 0.3 0.018 13.7 0.3 1.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 PQQ_2 PF13360.6 CDJ45418.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.4 1 1 0 1 1 1 0 PQQ-like domain Snf7 PF03357.21 CDJ45419.1 - 3e-19 69.3 13.5 3e-19 69.3 13.5 3.4 3 1 0 3 3 3 1 Snf7 SUD-M PF11633.8 CDJ45420.1 - 0.0097 15.6 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Single-stranded poly(A) binding domain DUF2489 PF10675.9 CDJ45420.1 - 0.02 14.8 4.8 0.034 14.1 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) DUF2140 PF09911.9 CDJ45420.1 - 0.054 13.0 0.6 0.066 12.8 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) FAM193_C PF15914.5 CDJ45420.1 - 0.21 11.4 1.9 0.93 9.3 0.2 2.1 2 0 0 2 2 2 0 FAM193 family C-terminal FTZ PF03867.14 CDJ45420.1 - 0.28 10.7 1.7 0.29 10.6 1.7 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region DUF1972 PF09314.11 CDJ45421.1 - 1.9e-89 298.2 1.4 3.5e-89 297.3 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1972) Glycos_transf_1 PF00534.20 CDJ45421.1 - 2.3e-05 24.0 0.1 7.8e-05 22.3 0.0 1.8 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ45421.1 - 5.2e-05 23.7 0.0 0.00015 22.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CDJ45421.1 - 0.0085 16.1 0.0 0.027 14.5 0.0 1.9 2 1 0 2 2 2 1 Glycosyltransferase Family 4 PP2C PF00481.21 CDJ45423.1 - 2.4e-58 197.8 0.0 3e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ45423.1 - 0.037 13.7 0.0 0.081 12.5 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C SpoIIE PF07228.12 CDJ45423.1 - 0.055 13.4 0.0 2.8 7.8 0.0 2.6 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Telomerase_RBD PF12009.8 CDJ45424.1 - 7.1e-29 100.6 0.0 7.1e-29 100.6 0.0 2.3 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain DUF5580 PF17743.1 CDJ45425.1 - 0.026 13.1 0.6 0.034 12.7 0.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) PGK PF00162.19 CDJ45427.1 - 6.2e-92 308.4 0.0 8.1e-92 308.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase SR-25 PF10500.9 CDJ45427.1 - 0.031 13.9 0.4 0.058 13.0 0.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Acyltransferase PF01553.21 CDJ45428.1 - 0.17 11.5 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Acyltransferase Thymidylate_kin PF02223.17 CDJ45431.1 - 4.1e-28 98.3 0.0 4.8e-24 85.1 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 CDJ45431.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ45431.1 - 0.03 14.7 0.5 0.036 14.4 0.5 1.3 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 CDJ45431.1 - 0.035 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase PsbQ PF05757.11 CDJ45431.1 - 0.059 13.1 1.6 0.092 12.5 1.6 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) ADK PF00406.22 CDJ45431.1 - 0.075 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase CCAP PF11105.8 CDJ45431.1 - 0.11 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a KTI12 PF08433.10 CDJ45431.1 - 0.17 11.3 0.0 0.21 11.0 0.0 1.3 1 1 0 1 1 1 0 Chromatin associated protein KTI12 MccV PF17508.2 CDJ45431.1 - 0.29 11.7 3.9 0.49 11.0 3.9 1.3 1 0 0 1 1 1 0 Microcin V bacteriocin SUIM_assoc PF16619.5 CDJ45432.1 - 0.008 16.2 5.8 0.008 16.2 5.8 19.8 6 3 6 12 12 12 2 Unstructured region C-term to UIM in Ataxin3 DEAD PF00270.29 CDJ45434.1 - 3.4e-41 140.9 0.0 2e-40 138.4 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ45434.1 - 0.0029 17.6 0.4 0.012 15.6 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ45434.1 - 0.023 15.0 0.2 0.15 12.4 0.2 2.2 1 1 0 1 1 1 0 AAA domain DUF498 PF04430.14 CDJ45434.1 - 0.83 9.8 3.0 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) DUF4472 PF14739.6 CDJ45435.1 - 0.0084 16.8 13.4 0.0098 16.6 13.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) ZapB PF06005.12 CDJ45435.1 - 0.0095 16.4 3.4 0.0095 16.4 3.4 2.1 1 1 1 2 2 2 1 Cell division protein ZapB Bap31_Bap29_C PF18035.1 CDJ45435.1 - 0.014 15.4 1.0 0.014 15.4 1.0 2.5 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF948 PF06103.11 CDJ45435.1 - 0.3 11.4 2.2 0.82 10.0 2.2 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CENP-H PF05837.12 CDJ45435.1 - 0.79 10.1 13.5 0.96 9.9 13.5 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3340 PF11818.8 CDJ45435.1 - 0.88 9.7 12.1 0.99 9.6 12.1 1.1 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF4407 PF14362.6 CDJ45435.1 - 0.96 8.7 16.5 1 8.6 16.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 CDJ45435.1 - 0.98 10.1 9.1 1.3 9.7 9.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF2076 PF09849.9 CDJ45435.1 - 1.3 9.1 19.1 1.5 8.8 19.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Macoilin PF09726.9 CDJ45435.1 - 1.9 7.0 14.9 2.3 6.7 14.9 1.2 1 0 0 1 1 1 0 Macoilin family ALMT PF11744.8 CDJ45435.1 - 2.1 7.1 6.3 2.3 7.0 6.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter PRKG1_interact PF15898.5 CDJ45435.1 - 3.2 8.7 15.7 23 6.0 15.7 1.9 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain V_ATPase_I PF01496.19 CDJ45435.1 - 5 4.9 12.0 5.2 4.8 12.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 CDJ45435.1 - 5.8 7.4 20.7 15 6.1 20.7 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Adaptin_N PF01602.20 CDJ45436.1 - 7.3e-36 123.8 0.0 9.1e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDJ45436.1 - 2.8e-07 30.7 0.0 4.5e-05 23.6 0.0 2.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ45436.1 - 0.0009 19.6 0.1 0.016 15.6 0.0 2.7 2 1 0 2 2 2 1 HEAT repeats Peptidase_C48 PF02902.19 CDJ45438.1 - 3.7e-11 43.3 0.1 5.7e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Spt20 PF12090.8 CDJ45438.1 - 0.5 9.9 13.5 0.86 9.2 13.5 1.3 1 0 0 1 1 1 0 Spt20 family Trp_oprn_chp PF09534.10 CDJ45439.1 - 0.089 12.6 7.1 0.15 11.9 7.1 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3357 PF11837.8 CDJ45439.1 - 0.49 10.9 3.2 0.46 11.0 1.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) BatA PF07584.11 CDJ45439.1 - 4.1 7.8 7.9 1.9 8.9 2.1 2.7 2 1 0 2 2 2 0 Aerotolerance regulator N-terminal zf-met PF12874.7 CDJ45440.1 - 0.00011 22.5 1.8 0.00023 21.4 1.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ45440.1 - 0.00014 22.0 1.4 0.00014 22.0 1.4 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF1690 PF07956.11 CDJ45440.1 - 0.16 12.4 2.2 0.13 12.7 0.4 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) zf-U1 PF06220.12 CDJ45440.1 - 0.26 11.1 0.9 0.63 9.9 0.9 1.5 1 0 0 1 1 1 0 U1 zinc finger DASH_Spc19 PF08287.11 CDJ45440.1 - 2.9 7.8 8.0 0.095 12.6 0.5 2.3 3 0 0 3 3 3 0 Spc19 Proteasome PF00227.26 CDJ45441.1 - 1.8e-49 167.8 0.1 2.5e-49 167.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Dpy-30 PF05186.13 CDJ45444.1 - 0.01 15.5 2.7 0.22 11.2 0.1 2.6 2 0 0 2 2 2 2 Dpy-30 motif cNMP_binding PF00027.29 CDJ45445.1 - 7e-08 32.4 0.0 6.1e-07 29.4 0.0 2.5 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain Eryth_link_C PF16915.5 CDJ45445.1 - 0.014 15.4 0.2 0.041 13.9 0.0 1.8 2 0 0 2 2 2 0 Annelid erythrocruorin linker subunit C-terminus BAF1_ABF1 PF04684.13 CDJ45448.1 - 3.7 6.5 7.6 4.6 6.2 7.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CPSF100_C PF13299.6 CDJ45448.1 - 3.9 7.6 6.0 5.3 7.2 6.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Roughex PF06020.11 CDJ45448.1 - 4.7 6.2 7.9 6.3 5.8 7.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PepSY_2 PF13670.6 CDJ45448.1 - 7.3 6.7 9.6 13 5.8 9.6 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Spt20 PF12090.8 CDJ45448.1 - 7.6 6.1 8.5 9.9 5.7 8.5 1.1 1 0 0 1 1 1 0 Spt20 family DXP_synthase_N PF13292.6 CDJ45450.1 - 5e-54 183.3 0.0 4e-53 180.4 0.0 2.0 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 CDJ45450.1 - 6.6e-32 110.6 0.0 1.5e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CDJ45450.1 - 0.00048 19.2 0.0 0.00084 18.4 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 CDJ45450.1 - 0.00077 18.5 0.0 0.13 11.2 0.0 2.2 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain DUF4667 PF15700.5 CDJ45450.1 - 0.0034 17.5 0.3 0.006 16.7 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) TPP_enzyme_C PF02775.21 CDJ45450.1 - 0.0041 16.9 0.0 0.0041 16.9 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SPX PF03105.19 CDJ45450.1 - 0.19 11.6 2.3 0.25 11.2 2.3 1.2 1 0 0 1 1 1 0 SPX domain IMUP PF15761.5 CDJ45450.1 - 1.9 9.2 16.3 6.7 7.4 16.3 1.9 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF3446 PF11928.8 CDJ45450.1 - 7 7.0 19.5 15 5.9 17.4 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain Ctr PF04145.15 CDJ45451.1 - 0.032 14.8 3.1 0.99 10.0 0.2 2.6 2 0 0 2 2 2 0 Ctr copper transporter family Trm112p PF03966.16 CDJ45452.1 - 7.2e-09 36.1 5.5 4.8e-08 33.5 5.5 2.4 1 1 0 1 1 1 1 Trm112p-like protein TFIIA PF03153.13 CDJ45452.1 - 0.0049 16.9 32.6 0.0064 16.5 32.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CCSAP PF15748.5 CDJ45452.1 - 0.019 15.2 14.4 0.024 14.8 14.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SR-25 PF10500.9 CDJ45452.1 - 0.021 14.5 11.6 0.031 13.9 11.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Corona_nucleoca PF00937.18 CDJ45452.1 - 0.067 12.2 16.1 0.093 11.7 16.1 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein MMR1 PF08505.10 CDJ45452.1 - 0.073 13.4 17.2 0.089 13.1 17.2 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FapA PF03961.13 CDJ45452.1 - 0.84 8.2 9.7 1.1 7.8 9.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Radical_SAM_N PF08497.10 CDJ45452.1 - 1.2 8.4 4.9 1.6 7.9 4.9 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal Presenilin PF01080.17 CDJ45452.1 - 1.4 7.6 14.4 1.7 7.4 14.4 1.1 1 0 0 1 1 1 0 Presenilin Exonuc_VII_L PF02601.15 CDJ45452.1 - 2 7.9 21.5 2.5 7.6 21.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAT1 PF09770.9 CDJ45452.1 - 4.7 5.4 28.5 5.7 5.1 28.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ45452.1 - 8.8 6.3 9.9 11 5.9 9.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MITF_TFEB_C_3_N PF15951.5 CDJ45454.1 - 0.013 16.1 3.0 0.013 16.1 3.0 2.4 2 0 0 2 2 2 0 MITF/TFEB/TFEC/TFE3 N-terminus RNA_pol_Rpc34 PF05158.12 CDJ45454.1 - 1.5 8.2 3.9 25 4.1 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpc34 subunit HHH_6 PF14579.6 CDJ45456.1 - 0.065 13.5 0.1 0.073 13.3 0.1 1.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif Zip PF02535.22 CDJ45457.1 - 4.9 6.3 6.8 9.8 5.3 6.8 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4200 PF13863.6 CDJ45458.1 - 2.9 8.3 16.1 0.11 12.8 0.6 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) SET PF00856.28 CDJ45459.1 - 3.4e-09 37.3 0.4 1.7e-08 35.1 0.1 1.9 2 1 0 2 2 2 1 SET domain TBCC PF07986.12 CDJ45461.1 - 0.026 14.2 0.1 0.093 12.5 0.0 1.9 1 1 1 2 2 2 0 Tubulin binding cofactor C SMC_N PF02463.19 CDJ45462.1 - 2.2e-51 174.4 0.0 4.5e-51 173.4 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDJ45462.1 - 2.8e-13 50.2 0.1 2.6e-12 47.1 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CDJ45462.1 - 6.1e-09 36.1 8.5 0.00022 21.1 0.3 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDJ45462.1 - 7.1e-06 26.0 8.3 7.1e-06 26.0 8.3 4.0 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CDJ45462.1 - 0.00037 20.2 0.0 0.00084 19.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6_N PF17675.1 CDJ45462.1 - 0.00041 20.9 17.7 0.00041 20.9 17.7 8.6 3 3 4 8 8 8 2 Apg6 coiled-coil region ABC_tran PF00005.27 CDJ45462.1 - 0.0011 19.5 0.4 0.0031 18.0 0.3 6.5 4 2 1 5 5 5 2 ABC transporter DUF1409 PF07197.12 CDJ45462.1 - 0.024 14.5 0.2 0.24 11.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) DUF4320 PF14208.6 CDJ45462.1 - 0.98 9.5 5.0 0.93 9.6 1.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) IMCp PF12314.8 CDJ45465.1 - 6.9e-16 58.3 50.9 2.3e-12 47.0 27.8 2.1 1 1 1 2 2 2 2 Inner membrane complex protein IMCp PF12314.8 CDJ45466.1 - 1.7e-25 89.1 55.0 2.6e-24 85.3 36.9 2.1 1 1 1 2 2 2 2 Inner membrane complex protein V-ATPase_G PF03179.15 CDJ45468.1 - 0.0016 18.9 7.6 0.0027 18.2 7.6 1.4 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ABA_GPCR PF12430.8 CDJ45469.1 - 2.6e-33 115.3 9.0 2.6e-33 115.3 9.0 1.9 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CDJ45469.1 - 3.2e-17 62.4 1.9 7e-17 61.3 0.0 2.4 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal MscS_porin PF12795.7 CDJ45469.1 - 2.2 7.8 5.2 0.32 10.5 0.7 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain WD40 PF00400.32 CDJ45470.1 - 3.9e-23 81.3 11.0 5.9e-07 30.1 0.8 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ45470.1 - 8.8e-14 51.6 0.0 0.0029 17.9 0.0 5.3 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDJ45470.1 - 0.036 14.0 0.0 24 4.7 0.0 3.7 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDJ45470.1 - 0.068 12.1 0.1 18 4.1 0.0 3.5 3 2 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1722 PF08349.11 CDJ45471.1 - 0.0025 18.1 1.0 0.0062 16.8 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1722) Phasin PF05597.11 CDJ45471.1 - 0.02 14.9 2.2 0.18 11.8 0.2 2.7 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SLATT_1 PF18181.1 CDJ45471.1 - 0.07 13.1 1.6 0.13 12.2 0.3 2.1 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 UCR_Fe-S_N PF10399.9 CDJ45471.1 - 0.21 11.0 0.8 0.38 10.1 0.8 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal dCMP_cyt_deam_1 PF00383.23 CDJ45472.1 - 1.1e-22 79.8 2.1 1.1e-22 79.8 2.1 1.8 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDJ45472.1 - 7.8e-14 51.6 0.1 1.4e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase MGAT2 PF05060.14 CDJ45472.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) Cpn60_TCP1 PF00118.24 CDJ45473.1 - 5e-150 500.4 8.6 5.7e-150 500.2 8.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Spt20 PF12090.8 CDJ45474.1 - 0.012 15.3 10.4 0.012 15.3 10.4 2.6 3 0 0 3 3 3 0 Spt20 family DUF2722 PF10846.8 CDJ45474.1 - 0.043 12.8 13.8 0.011 14.7 6.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ45474.1 - 0.1 13.6 5.8 6.9 7.7 4.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) EPL1 PF10513.9 CDJ45474.1 - 0.14 12.5 3.8 0.45 10.9 2.1 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like OATP PF03137.20 CDJ45474.1 - 0.17 10.2 0.1 0.23 9.7 0.1 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family USP8_interact PF08941.10 CDJ45474.1 - 0.24 11.2 3.5 0.6 9.9 3.5 1.7 1 0 0 1 1 1 0 USP8 interacting Presenilin PF01080.17 CDJ45474.1 - 1.3 7.7 6.5 1.3 7.7 5.2 1.6 2 0 0 2 2 2 0 Presenilin BAF1_ABF1 PF04684.13 CDJ45474.1 - 3.9 6.4 12.0 0.067 12.2 3.8 1.8 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF5327 PF17261.2 CDJ45474.1 - 4.6 8.0 15.7 7.3 7.4 5.9 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Gti1_Pac2 PF09729.9 CDJ45474.1 - 7.3 6.6 7.0 0.83 9.7 0.5 2.2 2 1 0 2 2 2 0 Gti1/Pac2 family RR_TM4-6 PF06459.12 CDJ45474.1 - 8 6.2 9.4 11 5.8 6.4 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Aha1_N PF09229.11 CDJ45476.1 - 5.9e-08 33.0 0.0 8.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal TFIIA PF03153.13 CDJ45476.1 - 0.13 12.3 18.0 0.16 12.0 18.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ45476.1 - 1.3 9.7 9.8 0.61 10.7 7.0 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Suf PF05843.14 CDJ45476.1 - 3.2 7.7 8.4 4.1 7.3 8.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ATP11 PF06644.11 CDJ45476.1 - 5.7 6.7 10.6 88 2.7 10.7 2.0 1 1 1 2 2 2 0 ATP11 protein SR-25 PF10500.9 CDJ45477.1 - 0.71 9.4 4.8 0.9 9.1 4.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GDPD PF03009.17 CDJ45478.1 - 3.1e-05 23.8 0.0 0.00024 20.9 0.0 2.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Collagen PF01391.18 CDJ45479.1 - 0.00019 21.1 24.6 0.00019 21.1 24.6 4.3 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Ribosomal_60s PF00428.19 CDJ45480.1 - 2.5 8.8 12.0 1.2 9.7 8.4 2.1 2 1 0 2 2 2 0 60s Acidic ribosomal protein DUF3675 PF12428.8 CDJ45481.1 - 3.3 8.3 8.8 5.4 7.6 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3675) POT1 PF02765.17 CDJ45482.1 - 0.0023 17.7 0.1 0.0037 17.1 0.1 1.2 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Filo_VP35 PF02097.15 CDJ45482.1 - 0.014 14.5 0.8 0.023 13.7 0.8 1.3 1 0 0 1 1 1 0 Filoviridae VP35 Spc7 PF08317.11 CDJ45482.1 - 0.018 14.0 9.9 0.025 13.4 9.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF812 PF05667.11 CDJ45482.1 - 0.018 13.9 10.7 0.02 13.8 10.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 CDJ45482.1 - 0.02 14.9 1.6 0.02 14.9 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PEARLI-4 PF05278.12 CDJ45482.1 - 0.032 13.8 6.0 0.045 13.4 6.0 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Atg14 PF10186.9 CDJ45482.1 - 0.053 12.6 4.9 0.066 12.3 4.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ORC3_N PF07034.11 CDJ45482.1 - 0.062 12.4 3.6 0.087 11.9 3.6 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Mod_r PF07200.13 CDJ45482.1 - 0.11 12.7 12.4 0.048 13.8 10.2 1.5 2 0 0 2 2 1 0 Modifier of rudimentary (Mod(r)) protein Dna2 PF08696.11 CDJ45482.1 - 0.15 11.9 2.8 0.24 11.2 2.8 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 Exonuc_VII_L PF02601.15 CDJ45482.1 - 0.19 11.2 7.0 0.21 11.1 7.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.11 CDJ45482.1 - 0.32 11.1 4.2 0.68 10.0 4.2 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 CDJ45482.1 - 0.33 10.1 4.8 0.46 9.7 4.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 CDJ45482.1 - 0.87 7.4 6.4 1.1 7.2 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 CDJ45482.1 - 0.89 8.4 2.9 1 8.2 2.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Tropomyosin_1 PF12718.7 CDJ45482.1 - 1.1 9.4 18.9 0.084 13.0 12.7 2.0 2 1 0 2 2 2 0 Tropomyosin like DUF2203 PF09969.9 CDJ45482.1 - 1.3 9.8 9.2 2.6 8.8 8.1 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Fmp27_WPPW PF10359.9 CDJ45482.1 - 2.2 7.0 8.9 3.1 6.5 8.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Cas_CT1975 PF09344.10 CDJ45482.1 - 3.1 7.2 14.0 1.1 8.6 9.3 2.0 1 1 1 2 2 1 0 CT1975-like protein GrpE PF01025.19 CDJ45482.1 - 4 7.1 13.8 6.4 6.4 10.9 2.2 1 1 1 2 2 2 0 GrpE EMC3_TMCO1 PF01956.16 CDJ45482.1 - 7.2 6.3 7.3 11 5.7 7.3 1.4 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Ribosomal_L15e PF00827.17 CDJ45483.1 - 0.085 12.6 2.6 0.18 11.5 2.6 1.4 1 0 0 1 1 1 0 Ribosomal L15 Metallothio_2 PF01439.18 CDJ45485.1 - 2.6 9.0 23.4 4.5 8.2 11.3 2.3 1 1 1 2 2 2 0 Metallothionein SRP-alpha_N PF04086.13 CDJ45485.1 - 3.3 7.5 13.5 4.1 7.2 13.5 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF5349 PF17298.2 CDJ45485.1 - 6 6.5 24.9 7 6.3 24.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Ribonuclease_3 PF00636.26 CDJ45486.1 - 0.15 12.7 1.1 0.57 10.8 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease III domain DUF2870 PF11069.8 CDJ45486.1 - 1.2 9.5 6.8 4.3 7.8 0.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) DUF4179 PF13786.6 CDJ45486.1 - 2 8.9 0.0 2 8.9 0.0 5.9 5 2 0 5 5 5 0 Domain of unknown function (DUF4179) MFS_2 PF13347.6 CDJ45487.1 - 0.002 16.8 1.3 0.0025 16.4 1.3 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein SR-25 PF10500.9 CDJ45488.1 - 0.00017 21.3 7.1 0.00026 20.7 7.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDK2AP PF09806.9 CDJ45488.1 - 0.0028 17.8 3.7 0.0028 17.8 3.7 1.7 2 0 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein Mlh1_C PF16413.5 CDJ45488.1 - 0.1 12.0 6.2 0.074 12.4 0.3 2.3 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus CRR7 PF12095.8 CDJ45488.1 - 0.39 11.2 0.0 0.39 11.2 0.0 3.4 4 1 0 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 Membr_traf_MHD PF10540.9 CDJ45488.1 - 0.89 9.7 7.3 0.12 12.6 0.4 2.4 2 1 0 2 2 2 0 Munc13 (mammalian uncoordinated) homology domain CCSAP PF15748.5 CDJ45488.1 - 0.91 9.6 9.3 0.14 12.3 5.3 1.7 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated TSA PF03249.13 CDJ45488.1 - 6.7 5.4 7.6 9.7 4.8 1.3 2.1 2 0 0 2 2 2 0 Type specific antigen UbiA PF01040.18 CDJ45489.1 - 3e-28 98.8 22.2 3e-28 98.8 22.2 3.2 1 1 1 2 2 2 1 UbiA prenyltransferase family SARAF PF06682.12 CDJ45489.1 - 0.00026 20.8 2.1 0.0004 20.2 2.1 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis SR-25 PF10500.9 CDJ45489.1 - 5.6 6.5 15.4 12 5.4 15.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ45490.1 - 0.0013 19.0 4.6 0.033 14.4 0.1 2.2 2 0 0 2 2 2 2 Centriole, cilia and spindle-associated SR-25 PF10500.9 CDJ45490.1 - 0.34 10.5 8.1 0.18 11.4 1.6 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SufE PF02657.15 CDJ45491.1 - 2.6e-11 43.4 0.2 3.1e-11 43.2 0.2 1.1 1 0 0 1 1 1 1 Fe-S metabolism associated domain Ribosomal_60s PF00428.19 CDJ45491.1 - 0.0028 18.2 5.4 0.0031 18.1 5.4 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.6 CDJ45491.1 - 1 9.4 8.8 1.3 9.1 8.8 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective SR-25 PF10500.9 CDJ45493.1 - 0.0012 18.5 6.0 0.0012 18.5 6.0 4.3 3 1 1 4 4 4 3 Nuclear RNA-splicing-associated protein DUF4179 PF13786.6 CDJ45493.1 - 2.8 8.5 19.3 3.4 8.2 2.4 5.2 2 2 0 3 3 3 0 Domain of unknown function (DUF4179) RRM_1 PF00076.22 CDJ45495.1 - 1.2e-11 44.3 0.0 1.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 CDJ45495.1 - 0.0086 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) RNA_bind PF08675.11 CDJ45495.1 - 0.029 14.4 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain DUF4701 PF15773.5 CDJ45495.1 - 0.084 11.9 3.0 0.18 10.8 3.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4701) RRM_7 PF16367.5 CDJ45495.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ45495.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PAT1 PF09770.9 CDJ45496.1 - 0.24 9.6 64.7 0.32 9.2 64.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SUIM_assoc PF16619.5 CDJ45497.1 - 0.05 13.7 18.5 0.053 13.6 7.1 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ45497.1 - 0.58 10.4 0.0 0.58 10.4 0.0 3.2 2 1 1 3 3 3 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ45497.1 - 0.61 10.0 24.8 0.043 13.8 11.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DLIC PF05783.11 CDJ45497.1 - 0.96 8.2 4.4 1 8.1 2.2 1.9 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) RAP1 PF07218.11 CDJ45497.1 - 3.7 5.7 5.8 4.9 5.3 5.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PP2C PF00481.21 CDJ45498.1 - 1.1e-29 103.9 0.0 1.3e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ45498.1 - 0.0012 18.8 0.0 0.0075 16.2 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CDJ45498.1 - 0.0033 17.1 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C CUE PF02845.16 CDJ45498.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 CUE domain PAT1 PF09770.9 CDJ45499.1 - 0.02 13.2 17.3 0.02 13.2 17.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ45499.1 - 0.34 10.7 6.7 0.52 10.1 6.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tae4 PF14113.6 CDJ45499.1 - 0.62 10.3 4.5 1.1 9.5 4.5 1.3 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase effector protein 4 Renin_r PF07850.14 CDJ45499.1 - 0.84 10.3 6.0 1.3 9.6 0.6 2.5 2 0 0 2 2 2 0 Renin receptor-like protein SNF2_N PF00176.23 CDJ45500.1 - 1.8e-15 56.5 0.0 2.8e-13 49.3 0.0 2.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 CDJ45500.1 - 0.00075 19.2 0.2 0.015 15.0 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF305 PF03713.13 CDJ45500.1 - 0.0062 16.7 1.5 0.01 16.0 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF305) Speriolin_N PF15058.6 CDJ45500.1 - 0.018 15.2 4.0 0.036 14.1 4.0 1.5 1 0 0 1 1 1 0 Speriolin N terminus COMMD1_N PF17221.3 CDJ45500.1 - 0.078 13.3 0.6 0.21 11.9 0.6 1.7 1 0 0 1 1 1 0 COMMD1 N-terminal domain SR-25 PF10500.9 CDJ45500.1 - 0.28 10.8 7.1 0.53 9.8 7.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ45500.1 - 1.5 8.8 5.0 2 8.3 5.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF755 PF05501.11 CDJ45500.1 - 1.7 8.9 13.9 0.19 12.0 5.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) TFIIA PF03153.13 CDJ45502.1 - 1.1 9.2 3.8 1.3 9.0 3.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4614 PF15391.6 CDJ45503.1 - 0.17 11.9 4.5 0.17 11.9 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 CDJ45503.1 - 6.1 5.6 5.3 5.6 5.7 5.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Imm5 PF14423.6 CDJ45504.1 - 0.17 12.1 0.2 0.26 11.5 0.2 1.2 1 0 0 1 1 1 0 Immunity protein Imm5 DUF4632 PF15451.6 CDJ45504.1 - 1.7 8.8 8.7 0.091 12.8 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4632) BLOC1S3 PF15753.5 CDJ45505.1 - 0.042 14.0 9.0 0.6 10.2 0.3 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 UPF0449 PF15136.6 CDJ45505.1 - 0.52 10.8 4.4 1.2 9.6 3.8 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Adaptin_binding PF10199.9 CDJ45507.1 - 0.0053 17.3 0.0 0.072 13.7 0.0 2.8 3 1 0 3 3 3 1 Alpha and gamma adaptin binding protein p34 DUF1068 PF06364.12 CDJ45507.1 - 0.011 15.6 3.1 0.011 15.6 3.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1068) DUF1360 PF07098.11 CDJ45507.1 - 7.9 6.5 10.1 2.9 7.9 0.9 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) NFACT-R_1 PF05670.13 CDJ45508.1 - 8.5e-39 132.6 0.0 1.2e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain Glucan_synthase PF02364.15 CDJ45508.1 - 0.51 8.4 2.4 0.58 8.3 2.4 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component DUF2605 PF10792.9 CDJ45508.1 - 6.2 6.8 9.1 8.5 6.4 7.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) SAC3_GANP PF03399.16 CDJ45509.1 - 5.4e-11 42.4 10.3 5.4e-11 42.4 10.3 1.4 1 1 1 2 2 2 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CDJ45509.1 - 0.0018 18.2 1.4 0.0025 17.8 1.4 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family F-112 PF09645.10 CDJ45509.1 - 0.01 16.0 0.8 0.017 15.3 0.8 1.3 1 0 0 1 1 1 1 F-112 protein SUIM_assoc PF16619.5 CDJ45509.1 - 0.023 14.8 2.7 0.023 14.8 2.7 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ICE2 PF08426.10 CDJ45509.1 - 0.029 13.5 0.2 0.039 13.1 0.2 1.1 1 0 0 1 1 1 0 ICE2 Endonuc-BsobI PF09194.10 CDJ45510.1 - 0.0043 16.3 0.1 0.0081 15.4 0.1 1.5 1 1 0 1 1 1 1 Restriction endonuclease BsobI Bestrophin PF01062.21 CDJ45510.1 - 0.017 14.5 3.0 0.035 13.5 3.0 1.4 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF1682 PF07946.14 CDJ45510.1 - 0.49 9.6 5.2 0.92 8.6 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF702 PF05142.12 CDJ45510.1 - 1.6 9.2 4.3 1.8 9.0 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF2203 PF09969.9 CDJ45510.1 - 2.2 9.0 6.9 3 8.6 3.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) NUC173 PF08161.12 CDJ45511.1 - 2.1e-17 63.5 1.0 1.7e-15 57.3 0.2 3.8 3 1 0 3 3 3 1 NUC173 domain SUIM_assoc PF16619.5 CDJ45511.1 - 0.0082 16.2 7.0 0.095 12.8 1.9 2.6 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 HEAT PF02985.22 CDJ45511.1 - 2.8 8.4 20.5 1.1 9.7 0.3 5.7 5 0 0 5 5 5 0 HEAT repeat SOG2 PF10428.9 CDJ45512.1 - 0.091 12.0 26.5 0.14 11.3 26.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF572 PF04502.13 CDJ45512.1 - 1.8 8.1 10.6 6.7 6.2 10.7 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.9 CDJ45512.1 - 7.5 5.3 6.9 11 4.8 6.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nop53 PF07767.11 CDJ45513.1 - 4.4e-05 23.1 3.3 4.4e-05 23.1 3.3 1.5 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) FlxA PF14282.6 CDJ45513.1 - 0.87 9.6 14.5 1.9 8.5 13.6 1.8 2 0 0 2 2 2 0 FlxA-like protein Snapin_Pallidin PF14712.6 CDJ45513.1 - 5.9 7.4 11.4 7.4 7.1 7.8 2.1 2 0 0 2 2 2 0 Snapin/Pallidin RF-1 PF00472.20 CDJ45515.1 - 4.6e-21 74.9 12.9 6.6e-20 71.2 0.5 3.1 2 1 1 3 3 3 3 RF-1 domain FAD-oxidase_C PF02913.19 CDJ45515.1 - 0.079 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain SUIM_assoc PF16619.5 CDJ45517.1 - 0.13 12.3 45.4 0.12 12.5 1.1 5.2 4 2 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 CDJ45518.1 - 4.9e-15 55.1 0.0 5.4e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ45518.1 - 0.18 11.4 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MT-A70 PF05063.14 CDJ45519.1 - 2.9e-24 85.9 0.0 8.3e-24 84.4 0.0 1.8 1 1 0 1 1 1 1 MT-A70 SRP-alpha_N PF04086.13 CDJ45519.1 - 0.16 11.9 17.2 0.23 11.4 17.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SUIM_assoc PF16619.5 CDJ45520.1 - 0.054 13.6 29.4 0.48 10.5 8.9 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Med15 PF09606.10 CDJ45520.1 - 0.22 10.1 19.9 0.47 9.1 19.9 1.5 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CLN3 PF02487.17 CDJ45521.1 - 0.0043 16.2 5.7 0.0067 15.5 5.7 1.3 1 0 0 1 1 1 1 CLN3 protein DDHD PF02862.17 CDJ45521.1 - 0.016 15.3 2.4 0.029 14.5 2.4 1.5 1 0 0 1 1 1 0 DDHD domain DUF3292 PF11696.8 CDJ45521.1 - 0.017 13.6 1.0 0.028 12.8 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) RR_TM4-6 PF06459.12 CDJ45521.1 - 0.034 14.0 13.0 0.049 13.5 13.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ45521.1 - 0.038 14.0 5.0 0.063 13.3 5.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Pkinase_fungal PF17667.1 CDJ45521.1 - 0.048 12.4 1.0 0.061 12.1 1.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Ndc1_Nup PF09531.10 CDJ45521.1 - 0.27 9.9 9.9 0.37 9.4 9.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tim54 PF11711.8 CDJ45521.1 - 0.35 9.6 10.7 0.49 9.1 10.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PPL5 PF18168.1 CDJ45521.1 - 0.6 9.3 5.1 0.97 8.7 5.1 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF4746 PF15928.5 CDJ45521.1 - 0.61 9.5 10.5 0.86 9.0 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CCDC53 PF10152.9 CDJ45521.1 - 0.74 10.2 17.1 0.4 11.1 14.5 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Band_3_cyto PF07565.13 CDJ45521.1 - 1 9.1 8.5 1.8 8.3 8.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain NST1 PF13945.6 CDJ45521.1 - 1.2 9.2 18.7 2.1 8.4 18.7 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator SLC12 PF03522.15 CDJ45521.1 - 1.3 7.9 13.0 1.9 7.4 13.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ45521.1 - 1.4 7.6 19.4 2.2 6.9 19.4 1.2 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 CDJ45521.1 - 2 7.3 8.9 3.1 6.7 8.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Endostatin PF06482.11 CDJ45521.1 - 2.2 7.6 14.7 3.6 7.0 14.7 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Ctr PF04145.15 CDJ45521.1 - 2.5 8.7 6.7 5.5 7.6 6.7 1.5 1 0 0 1 1 1 0 Ctr copper transporter family SID-1_RNA_chan PF13965.6 CDJ45521.1 - 2.6 6.3 3.6 4.2 5.7 3.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2828 PF11443.8 CDJ45521.1 - 3 5.8 10.6 4.4 5.3 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2058 PF09831.9 CDJ45521.1 - 3.1 7.9 25.9 5.8 7.0 25.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) CPSF100_C PF13299.6 CDJ45521.1 - 3.8 7.6 11.5 9.2 6.4 11.5 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4638 PF15472.6 CDJ45521.1 - 3.9 7.2 10.1 5.7 6.6 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) NPR3 PF03666.13 CDJ45521.1 - 4 6.1 14.8 7.5 5.2 14.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 CDJ45521.1 - 5.6 5.0 14.0 7.8 4.5 14.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF3_subunit PF08597.10 CDJ45521.1 - 6.3 6.6 15.9 16 5.3 15.9 1.6 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SpoIIP PF07454.11 CDJ45521.1 - 9 5.7 15.2 15 5.0 15.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) BolA PF01722.18 CDJ45522.1 - 1.5e-24 86.0 0.2 2.2e-24 85.5 0.2 1.3 1 0 0 1 1 1 1 BolA-like protein STAS_2 PF13466.6 CDJ45522.1 - 1.1 9.7 9.3 6.9 7.1 0.3 3.2 3 0 0 3 3 3 0 STAS domain GUN4_N PF16416.5 CDJ45523.1 - 0.0041 17.1 0.2 0.0043 17.0 0.2 1.0 1 0 0 1 1 1 1 ARM-like repeat domain, GUN4-N terminal Surface_antigen PF11054.8 CDJ45524.1 - 2.9e-80 269.5 4.2 3.5e-80 269.2 4.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF2052 PF09747.9 CDJ45525.1 - 0.014 15.5 5.4 0.021 14.9 5.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF1682 PF07946.14 CDJ45525.1 - 0.03 13.6 13.1 0.043 13.0 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Dehydrin PF00257.19 CDJ45525.1 - 0.047 14.2 0.6 0.047 14.2 0.6 3.5 2 1 1 3 3 3 0 Dehydrin Spt20 PF12090.8 CDJ45525.1 - 0.87 9.2 8.7 1.4 8.5 8.7 1.3 1 0 0 1 1 1 0 Spt20 family ObR_Ig PF18589.1 CDJ45525.1 - 1.8 9.0 6.1 0.27 11.7 0.6 2.1 2 0 0 2 2 2 0 Obesity receptor immunoglobulin like domain DLIC PF05783.11 CDJ45525.1 - 3.6 6.3 6.1 5.7 5.7 6.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) PHD PF00628.29 CDJ45527.1 - 1.5e-12 47.2 7.2 1.5e-12 47.2 7.2 1.6 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 CDJ45527.1 - 1.5e-11 43.7 2.8 1.5e-11 43.7 2.8 2.1 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 CDJ45527.1 - 0.00057 19.8 4.7 0.00057 19.8 4.7 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 CDJ45527.1 - 0.00099 18.8 0.6 0.00099 18.8 0.6 2.4 2 1 1 3 3 3 1 PHD/FYVE-zinc-finger like domain FYVE_2 PF02318.16 CDJ45527.1 - 0.002 18.3 3.4 0.0044 17.2 3.4 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger C1_2 PF03107.16 CDJ45527.1 - 0.0038 17.5 6.8 0.0048 17.2 0.9 2.7 3 0 0 3 3 3 1 C1 domain CDC24_OB3 PF17244.2 CDJ45527.1 - 0.0095 15.7 3.3 0.015 15.1 3.3 1.4 1 1 0 1 1 1 1 Cell division control protein 24, OB domain 3 zf-UDP PF14569.6 CDJ45527.1 - 0.019 15.0 3.7 0.041 14.0 3.7 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger C1_1 PF00130.22 CDJ45527.1 - 0.028 14.3 0.9 0.028 14.3 0.9 2.5 2 1 1 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FlaF PF07309.11 CDJ45527.1 - 0.054 13.5 1.1 0.096 12.7 0.1 1.8 2 0 0 2 2 2 0 Flagellar protein FlaF MIT_C PF16565.5 CDJ45527.1 - 0.06 13.3 0.4 3.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Phospholipase D-like domain at C-terminus of MIT zf-RING_9 PF13901.6 CDJ45527.1 - 0.088 12.8 8.3 0.059 13.3 4.9 2.2 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon Med3 PF11593.8 CDJ45527.1 - 6.1 5.9 10.9 0.19 10.9 1.1 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF3273 PF11677.8 CDJ45528.1 - 9.1e-66 221.9 9.3 1.1e-65 221.6 9.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) TFIIA PF03153.13 CDJ45529.1 - 9.2 6.1 14.9 13 5.7 14.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIP5K PF01504.18 CDJ45530.1 - 0.13 11.5 0.9 0.2 10.9 0.9 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Sacchrp_dh_NADP PF03435.18 CDJ45530.1 - 0.73 10.1 7.0 1.4 9.2 7.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain IMUP PF15761.5 CDJ45530.1 - 2.2 9.0 55.6 0.33 11.7 9.5 3.9 4 0 0 4 4 4 0 Immortalisation up-regulated protein SfLAP PF11139.8 CDJ45530.1 - 3.1 7.2 12.1 0.2 11.1 6.2 2.0 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein DUF3533 PF12051.8 CDJ45530.1 - 6.8 5.5 5.4 15 4.4 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) F-actin_cap_A PF01267.17 CDJ45531.1 - 1e-05 25.1 0.0 1.4e-05 24.7 0.0 1.2 1 1 0 1 1 1 1 F-actin capping protein alpha subunit SR-25 PF10500.9 CDJ45531.1 - 0.0085 15.7 5.4 0.0085 15.7 5.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Pom PF17251.2 CDJ45531.1 - 0.018 14.4 0.2 0.018 14.4 0.2 1.2 1 0 0 1 1 1 0 Protochlamydia outer membrane protein FAM104 PF15434.6 CDJ45533.1 - 0.058 14.0 0.2 0.058 14.0 0.2 3.0 2 1 1 3 3 3 0 Family 104 SPX PF03105.19 CDJ45533.1 - 2.6 7.9 15.9 3.8 7.3 15.9 1.3 1 0 0 1 1 1 0 SPX domain SCIMP PF15050.6 CDJ45533.1 - 2.9 8.4 5.9 0.43 11.0 1.1 1.9 1 1 1 2 2 2 0 SCIMP protein Miga PF10265.9 CDJ45533.1 - 4 6.3 6.9 6.2 5.7 6.9 1.3 1 0 0 1 1 1 0 Mitoguardin Cyt-b5 PF00173.28 CDJ45534.1 - 1.9e-06 27.9 0.0 5.1e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain PSCyt3 PF07627.11 CDJ45534.1 - 0.051 13.8 2.0 0.051 13.8 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Lentivirus_VIF PF05851.11 CDJ45534.1 - 0.13 11.1 0.5 0.21 10.5 0.5 1.3 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) TFIIA PF03153.13 CDJ45534.1 - 8.4 6.3 16.0 24 4.8 16.0 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATP-synt PF00231.19 CDJ45535.1 - 4.1e-36 125.1 0.0 4.6e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase SUIM_assoc PF16619.5 CDJ45535.1 - 0.0026 17.8 3.3 0.0038 17.2 3.3 1.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Elong_Iki1 PF10483.9 CDJ45535.1 - 0.032 13.7 0.1 0.04 13.4 0.1 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 RskA PF10099.9 CDJ45535.1 - 0.35 11.1 5.8 0.62 10.3 5.8 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ45535.1 - 0.87 9.2 8.5 1.2 8.7 8.5 1.2 1 0 0 1 1 1 0 Spt20 family SAPS PF04499.15 CDJ45536.1 - 0.4 9.4 17.7 1.3 7.7 5.1 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein BAF1_ABF1 PF04684.13 CDJ45537.1 - 0.21 10.6 6.8 0.27 10.2 6.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Apt1 PF10351.9 CDJ45537.1 - 0.79 8.5 20.8 0.88 8.3 20.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ribosomal_60s PF00428.19 CDJ45537.1 - 4.1 8.1 10.7 6.4 7.4 10.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein GREB1 PF15782.5 CDJ45537.1 - 7.5 3.5 14.0 8.6 3.3 14.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 CDJ45537.1 - 8.8 4.3 8.5 9.2 4.3 8.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S64 PF08192.11 CDJ45537.1 - 9.9 4.5 15.4 11 4.4 15.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 Cpn60_TCP1 PF00118.24 CDJ45538.1 - 6.7e-29 100.9 0.0 7.9e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nup54 PF13874.6 CDJ45539.1 - 0.066 13.3 2.8 0.071 13.2 2.8 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Neur_chan_memb PF02932.16 CDJ45540.1 - 0.0036 17.4 6.2 0.0036 17.4 6.2 2.0 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ45540.1 - 0.0037 17.1 14.6 0.0037 17.1 14.6 2.1 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 CDJ45540.1 - 0.0086 16.5 8.2 0.0086 16.5 8.2 2.4 2 0 0 2 2 2 1 RNA polymerase III RPC4 EIF4E-T PF10477.9 CDJ45540.1 - 0.035 12.9 22.5 0.043 12.6 22.5 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF2052 PF09747.9 CDJ45540.1 - 0.049 13.7 32.0 0.093 12.9 22.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SpoIIP PF07454.11 CDJ45540.1 - 0.18 11.3 24.0 0.03 13.8 15.1 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2151 PF10221.9 CDJ45540.1 - 0.2 10.2 10.6 0.27 9.8 10.6 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Band_3_cyto PF07565.13 CDJ45540.1 - 0.24 11.2 21.2 0.061 13.1 13.3 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Slu7 PF11708.8 CDJ45540.1 - 0.42 10.3 29.6 0.037 13.8 19.9 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor AAA_23 PF13476.6 CDJ45540.1 - 0.49 10.9 27.5 0.77 10.2 15.2 2.3 2 0 0 2 2 2 0 AAA domain Tim54 PF11711.8 CDJ45540.1 - 0.82 8.4 22.5 0.084 11.6 14.7 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.12 CDJ45540.1 - 0.93 8.4 14.9 0.25 10.3 10.2 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Pex14_N PF04695.13 CDJ45540.1 - 1.1 9.9 32.6 0.21 12.3 19.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MMR1 PF08505.10 CDJ45540.1 - 1.3 9.2 29.5 0.14 12.5 17.1 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF3807 PF12720.7 CDJ45540.1 - 1.4 9.2 34.2 1.4 9.1 26.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) FAM91_C PF14648.6 CDJ45540.1 - 2 7.2 10.2 0.079 11.8 3.2 1.9 2 0 0 2 2 2 0 FAM91 C-terminus Presenilin PF01080.17 CDJ45540.1 - 2.1 7.0 30.6 0.29 9.8 22.6 2.0 2 0 0 2 2 2 0 Presenilin CPSF100_C PF13299.6 CDJ45540.1 - 2.6 8.2 26.8 0.48 10.6 17.2 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal BORG_CEP PF14957.6 CDJ45540.1 - 3.3 8.9 22.4 4.4 8.5 13.3 2.2 2 0 0 2 2 2 0 Cdc42 effector Cwf_Cwc_15 PF04889.12 CDJ45540.1 - 5.2 6.7 32.1 4.5 6.9 24.3 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pet20 PF08692.10 CDJ45540.1 - 5.5 7.7 9.4 2.8 8.7 3.7 2.4 2 0 0 2 2 2 0 Mitochondrial protein Pet20 CSRNP_N PF16019.5 CDJ45540.1 - 5.7 6.8 20.9 0.62 9.9 11.8 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus HGTP_anticodon2 PF12745.7 CDJ45540.1 - 6.6 6.1 23.8 1.2 8.6 14.4 2.1 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Spt20 PF12090.8 CDJ45540.1 - 6.7 6.3 63.6 4.1 7.0 11.9 2.2 2 0 0 2 2 2 0 Spt20 family TERB2 PF15101.6 CDJ45540.1 - 7.9 6.5 33.9 1.3 9.0 21.4 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Methyltransf_10 PF05971.12 CDJ45542.1 - 4e-43 147.9 0.5 3.7e-39 134.8 0.0 3.2 2 1 0 2 2 2 2 RNA methyltransferase Methyltransf_25 PF13649.6 CDJ45542.1 - 0.01 16.5 0.0 0.026 15.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CDJ45542.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 CDJ45542.1 - 0.028 15.1 0.0 0.053 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SR-25 PF10500.9 CDJ45542.1 - 0.036 13.7 9.1 0.053 13.1 9.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Methyltransf_11 PF08241.12 CDJ45542.1 - 0.04 14.5 0.0 0.084 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RPN13_C PF16550.5 CDJ45543.1 - 7.5e-12 45.4 4.0 7.5e-12 45.4 4.0 2.5 2 0 0 2 2 2 1 UCH-binding domain DUF2722 PF10846.8 CDJ45543.1 - 0.0012 17.8 4.0 0.0019 17.2 4.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) CPSF73-100_C PF11718.8 CDJ45543.1 - 0.16 11.5 2.4 1.9 8.0 0.2 2.5 3 0 0 3 3 3 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Coilin_N PF15862.5 CDJ45543.1 - 1.1 9.1 7.5 0.055 13.3 0.8 2.1 2 0 0 2 2 2 0 Coilin N-terminus Pannexin_like PF12534.8 CDJ45543.1 - 2.3 7.2 8.0 0.1 11.7 2.2 1.6 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 ACT PF01842.25 CDJ45544.1 - 1.2e-05 24.9 0.0 2.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 ACT domain SUIM_assoc PF16619.5 CDJ45544.1 - 0.0016 18.5 3.3 0.0016 18.5 3.3 2.6 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 ACT_7 PF13840.6 CDJ45544.1 - 0.028 14.2 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 ACT domain IMUP PF15761.5 CDJ45544.1 - 0.033 14.9 3.4 0.033 14.9 3.4 2.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein Ribosomal_60s PF00428.19 CDJ45544.1 - 0.063 13.9 2.0 0.063 13.9 2.0 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein SR-25 PF10500.9 CDJ45544.1 - 0.074 12.6 10.5 0.041 13.5 6.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GRP PF07172.11 CDJ45544.1 - 0.12 13.1 4.8 0.35 11.6 4.8 1.8 1 0 0 1 1 1 0 Glycine rich protein family DUF3824 PF12868.7 CDJ45544.1 - 0.17 12.6 17.9 0.26 12.0 4.4 3.1 3 0 0 3 3 3 0 Domain of unknwon function (DUF3824) TFIIA PF03153.13 CDJ45544.1 - 0.53 10.2 17.2 0.25 11.3 2.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ45544.1 - 4 7.7 27.2 51 4.1 11.2 2.8 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF2681 PF10883.8 CDJ45544.1 - 9.3 6.7 21.3 2.8 8.4 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) DUF755 PF05501.11 CDJ45545.1 - 0.0086 16.3 12.1 0.0086 16.3 12.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF755) Apt1 PF10351.9 CDJ45545.1 - 0.86 8.4 11.8 1 8.2 11.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ45545.1 - 2.6 6.7 5.5 3.3 6.4 5.5 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 CDJ45545.1 - 3.5 6.1 14.4 5 5.6 14.4 1.2 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 CDJ45545.1 - 6.3 6.3 43.1 4.4 6.8 41.4 1.5 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4614 PF15391.6 CDJ45546.1 - 0.64 10.0 11.5 0.69 9.9 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) NST1 PF13945.6 CDJ45546.1 - 0.7 10.0 6.0 0.71 9.9 6.0 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator NPR3 PF03666.13 CDJ45546.1 - 1.4 7.7 6.7 1.3 7.7 6.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1635 PF07795.11 CDJ45546.1 - 4.4 7.1 7.9 5 6.9 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Apt1 PF10351.9 CDJ45546.1 - 5 5.9 8.1 4.5 6.0 8.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3576 PF12100.8 CDJ45547.1 - 0.034 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) DEAD_assoc PF08494.11 CDJ45548.1 - 0.025 14.4 0.1 0.026 14.3 0.1 1.1 1 0 0 1 1 1 0 DEAD/H associated DUF2722 PF10846.8 CDJ45549.1 - 0.13 11.2 5.3 0.056 12.4 3.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TMEM51 PF15345.6 CDJ45549.1 - 0.39 10.5 3.5 0.53 10.1 3.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Roughex PF06020.11 CDJ45549.1 - 0.58 9.2 7.4 0.72 8.9 7.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CKAP2_C PF15297.6 CDJ45549.1 - 0.8 8.7 6.0 0.34 10.0 3.8 1.4 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus Spt20 PF12090.8 CDJ45549.1 - 1.5 8.4 11.3 2.6 7.6 11.3 1.4 1 0 0 1 1 1 0 Spt20 family HU-CCDC81_bac_2 PF18175.1 CDJ45550.1 - 0.0032 17.3 0.9 0.0032 17.3 0.9 2.1 1 1 1 2 2 2 1 CCDC81-like prokaryotic HU domain 2 KfrA_N PF11740.8 CDJ45550.1 - 0.2 12.3 14.2 0.27 11.9 14.2 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Malate_synthase PF01274.22 CDJ45550.1 - 0.68 8.1 7.1 0.7 8.1 7.1 1.0 1 0 0 1 1 1 0 Malate synthase ALMT PF11744.8 CDJ45550.1 - 0.77 8.5 6.0 0.85 8.4 6.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter OmpH PF03938.14 CDJ45550.1 - 1.6 9.0 21.3 1.7 9.0 21.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Arm-DNA-bind_5 PF17293.2 CDJ45550.1 - 5.3 7.6 12.6 1.5e+02 2.9 12.6 2.2 1 1 0 1 1 1 0 Arm DNA-binding domain EMC3_TMCO1 PF01956.16 CDJ45550.1 - 5.4 6.7 10.9 6.2 6.5 10.9 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like YL1 PF05764.13 CDJ45551.1 - 5.5e-19 69.3 43.3 1.3e-18 68.1 43.3 1.6 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 CDJ45551.1 - 3.5e-09 36.3 0.1 5.4e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain RcsD_ABL PF16359.5 CDJ45551.1 - 0.0087 16.2 0.3 0.018 15.2 0.3 1.4 1 0 0 1 1 1 1 RcsD-ABL domain Miga PF10265.9 CDJ45551.1 - 1.4 7.8 16.0 0.37 9.7 12.6 1.8 2 0 0 2 2 2 0 Mitoguardin GREB1 PF15782.5 CDJ45551.1 - 6.8 3.7 29.5 9.3 3.2 29.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 CDJ45551.1 - 7.2 5.1 24.0 11 4.6 24.0 1.3 1 0 0 1 1 1 0 Hamartin protein AAA_lid_3 PF17862.1 CDJ45553.1 - 1.8e-14 53.3 0.0 2.9e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CDJ45553.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Peptidase_M11 PF05548.11 CDJ45555.1 - 1.3 8.1 5.6 0.33 10.1 2.7 1.3 1 1 0 1 1 1 0 Gametolysin peptidase M11 DUF2057 PF09829.9 CDJ45555.1 - 2.2 8.4 17.7 0.51 10.5 7.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Proteasome PF00227.26 CDJ45556.1 - 6.3e-12 45.4 0.2 1.2e-11 44.5 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit ABC1 PF03109.16 CDJ45557.1 - 7.7e-30 103.5 0.0 1.3e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Ribosomal_60s PF00428.19 CDJ45557.1 - 1.8 9.2 17.8 0.25 11.9 12.1 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein CAP PF00188.26 CDJ45558.1 - 7.7e-11 42.9 0.3 1.5e-10 42.0 0.3 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family TSP_1 PF00090.19 CDJ45558.1 - 0.0084 16.3 5.1 0.0084 16.3 5.1 3.6 3 0 0 3 3 3 1 Thrombospondin type 1 domain DUF3446 PF11928.8 CDJ45559.1 - 0.0017 18.6 3.3 0.0017 18.6 3.3 3.4 3 1 0 3 3 3 1 Early growth response N-terminal domain SR-25 PF10500.9 CDJ45559.1 - 0.19 11.3 30.6 0.19 11.3 3.1 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF4171 PF13775.6 CDJ45559.1 - 1.3 9.5 15.7 3.4 8.1 6.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4171) INSIG PF07281.12 CDJ45559.1 - 2.2 7.9 5.0 1.7 8.2 0.5 2.4 2 1 0 2 2 2 0 Insulin-induced protein (INSIG) Lin-8 PF03353.15 CDJ45559.1 - 6.6 6.2 26.3 0.054 13.1 7.9 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist MFS_1 PF07690.16 CDJ45560.1 - 1.2e-10 40.9 49.8 2.8e-09 36.4 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2140 PF09911.9 CDJ45560.1 - 0.016 14.8 0.4 0.027 14.0 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) PSD5 PF07637.11 CDJ45560.1 - 0.093 13.1 0.2 0.26 11.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) TFIIA PF03153.13 CDJ45560.1 - 0.13 12.3 11.4 0.15 12.0 11.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ45560.1 - 1.2 8.0 9.2 1.6 7.6 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TMEM51 PF15345.6 CDJ45560.1 - 2.1 8.1 7.0 0.34 10.7 3.0 1.6 2 0 0 2 2 2 0 Transmembrane protein 51 YfhO PF09586.10 CDJ45560.1 - 4.6 5.4 9.4 0.32 9.2 2.4 2.0 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF1611 PF07755.11 CDJ45561.1 - 0.25 10.6 0.0 0.25 10.6 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1611_C) P-loop domain GTP_EFTU PF00009.27 CDJ45562.1 - 3.1e-18 66.0 0.0 6.4e-18 65.0 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CDJ45562.1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D2 PF03144.25 CDJ45562.1 - 0.0012 19.2 0.3 0.0021 18.4 0.3 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ribosomal_60s PF00428.19 CDJ45562.1 - 0.0015 19.1 9.3 0.0015 19.1 9.3 2.0 3 0 0 3 3 3 1 60s Acidic ribosomal protein Ras PF00071.22 CDJ45562.1 - 0.006 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1_Xtn PF16897.5 CDJ45562.1 - 0.034 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RF3_C PF16658.5 CDJ45562.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain MnmE_helical PF12631.7 CDJ45562.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 2 0 0 2 2 2 0 MnmE helical domain RsgA_GTPase PF03193.16 CDJ45562.1 - 0.15 11.9 0.0 0.59 10.0 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase HEAT_2 PF13646.6 CDJ45563.1 - 7.2e-06 26.3 8.8 6.8e-05 23.2 1.3 2.9 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.22 CDJ45563.1 - 0.00011 22.2 4.0 0.23 11.8 0.1 4.6 4 0 0 4 4 4 2 HEAT repeat Cohesin_HEAT PF12765.7 CDJ45563.1 - 0.00095 19.4 0.9 0.19 12.1 0.1 3.3 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion DUF913 PF06025.12 CDJ45563.1 - 3.4 6.6 32.6 0.04 12.9 5.3 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) DUF3678 PF12435.8 CDJ45563.1 - 3.6 7.0 9.2 0.49 9.8 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Kringle PF00051.18 CDJ45565.1 - 5.4e-12 45.9 3.6 1.1e-11 44.9 3.6 1.5 1 0 0 1 1 1 1 Kringle domain MAR_sialic_bdg PF10564.9 CDJ45565.1 - 0.0022 18.0 0.1 0.0022 18.0 0.1 1.8 2 0 0 2 2 2 1 Sialic-acid binding micronemal adhesive repeat RCC1 PF00415.18 CDJ45566.1 - 5.2e-27 94.2 12.9 3.9e-09 37.0 0.3 7.0 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ45566.1 - 2.4e-22 78.2 19.4 1.1e-07 31.4 0.0 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat INTS5_N PF14837.6 CDJ45567.1 - 0.012 15.2 0.0 4.7 6.7 0.0 2.8 2 1 0 2 2 2 0 Integrator complex subunit 5 N-terminus MFS_2 PF13347.6 CDJ45567.1 - 0.056 12.0 0.1 0.084 11.4 0.1 1.3 1 0 0 1 1 1 0 MFS/sugar transport protein DUF2722 PF10846.8 CDJ45567.1 - 0.22 10.4 6.1 1.2 8.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) EF-hand_7 PF13499.6 CDJ45568.1 - 0.003 18.0 0.0 4.8 7.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair Hydrolase_6 PF13344.6 CDJ45569.1 - 2.4e-27 95.0 0.0 8.6e-27 93.2 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Ribosomal_L18p PF00861.22 CDJ45569.1 - 0.01 16.2 0.6 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast TFIIA PF03153.13 CDJ45569.1 - 0.013 15.5 9.1 0.015 15.3 9.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hydrolase PF00702.26 CDJ45569.1 - 0.045 14.0 0.2 0.068 13.4 0.0 1.7 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase XPG_I PF00867.18 CDJ45569.1 - 0.15 12.4 3.5 0.1 13.0 0.5 2.2 2 1 0 2 2 2 0 XPG I-region Presenilin PF01080.17 CDJ45569.1 - 0.74 8.5 5.0 0.99 8.1 5.0 1.1 1 0 0 1 1 1 0 Presenilin Dfp1_Him1_M PF08630.10 CDJ45569.1 - 2.8 8.2 5.9 27 5.0 0.1 2.1 1 1 1 2 2 2 0 Dfp1/Him1, central region DUF5323 PF17257.2 CDJ45570.1 - 2.2e-06 27.4 5.1 4.9e-06 26.3 5.1 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5323) Antimicrobial11 PF08106.11 CDJ45570.1 - 0.012 15.6 1.0 0.027 14.5 1.0 1.6 1 0 0 1 1 1 0 Formaecin family FDF PF09532.10 CDJ45570.1 - 1.5 9.7 3.4 0.67 10.9 0.3 2.0 2 1 0 2 2 2 0 FDF domain Spt20 PF12090.8 CDJ45571.1 - 0.53 9.9 5.0 0.59 9.7 5.0 1.1 1 0 0 1 1 1 0 Spt20 family Ribosomal_60s PF00428.19 CDJ45572.1 - 4.9 7.8 15.9 1.5 9.4 5.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein PDEase_I PF00233.19 CDJ45573.1 - 5.3e-22 78.7 0.0 6.3e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Planc_extracel PF07595.12 CDJ45573.1 - 0.15 11.9 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 Planctomycete extracellular ANAPC10 PF03256.16 CDJ45574.1 - 6.5e-38 130.2 0.0 9.7e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 CDJ45574.1 - 0.00077 19.6 0.0 0.0019 18.3 0.0 1.7 1 1 0 1 1 1 1 F5/8 type C domain Bindin PF02084.15 CDJ45574.1 - 2.7 8.2 5.8 5.7 7.1 5.8 1.4 1 0 0 1 1 1 0 Bindin WD40 PF00400.32 CDJ45575.1 - 5.4e-08 33.4 11.1 0.14 13.0 0.6 7.2 8 0 0 8 8 8 2 WD domain, G-beta repeat Lysis_col PF02402.16 CDJ45575.1 - 0.00031 20.3 1.1 0.01 15.5 0.2 3.3 2 0 0 2 2 2 1 Lysis protein HPS3_N PF14761.6 CDJ45575.1 - 0.0032 17.0 0.1 0.07 12.7 0.0 2.8 2 1 0 2 2 2 1 Hermansky-Pudlak syndrome 3 PC_rep PF01851.22 CDJ45577.1 - 1e-08 35.1 5.4 0.3 11.6 0.3 5.0 4 0 0 4 4 4 3 Proteasome/cyclosome repeat SR-25 PF10500.9 CDJ45577.1 - 0.0052 16.4 0.9 0.0052 16.4 0.9 8.5 8 1 1 9 9 9 3 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ45577.1 - 0.49 9.3 34.3 0.015 14.2 4.9 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2722) Dynein_AAA_lid PF17852.1 CDJ45577.1 - 0.75 9.9 0.0 0.75 9.9 0.0 2.6 3 0 0 3 3 3 0 Dynein heavy chain AAA lid domain Hydrolase_4 PF12146.8 CDJ45578.1 - 1.1e-09 37.9 7.8 2.5e-08 33.5 0.1 2.7 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Mito_fiss_reg PF05308.11 CDJ45578.1 - 0.068 13.2 6.8 0.16 12.0 6.8 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Ndc1_Nup PF09531.10 CDJ45578.1 - 1.7 7.3 5.5 2.4 6.7 5.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup VESA1_N PF12785.7 CDJ45579.1 - 2 7.3 16.0 2.5 7.0 16.0 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Spt20 PF12090.8 CDJ45579.1 - 3 7.4 8.0 3.1 7.3 8.0 1.1 1 0 0 1 1 1 0 Spt20 family NINJA_B PF16136.5 CDJ45579.1 - 7.4 7.0 9.8 11 6.4 9.7 1.4 1 1 0 1 1 1 0 Putative nuclear localisation signal LAP1C PF05609.12 CDJ45580.1 - 0.057 12.5 14.7 0.072 12.2 14.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF5423 PF17461.2 CDJ45580.1 - 7.8 5.2 18.5 12 4.6 18.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Ashwin PF15323.6 CDJ45581.1 - 0.2 11.6 14.8 0.36 10.8 14.8 1.4 1 1 0 1 1 1 0 Developmental protein SPX PF03105.19 CDJ45582.1 - 0.35 10.7 15.3 0.56 10.1 15.3 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ45582.1 - 0.36 9.6 8.6 0.52 9.1 8.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SUZ PF12752.7 CDJ45582.1 - 0.46 11.3 0.1 0.46 11.3 0.1 3.2 2 1 2 4 4 4 0 SUZ domain Glyco_hydro_9 PF00759.19 CDJ45582.1 - 0.76 9.1 11.5 0.95 8.8 11.5 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Adeno_PV PF03910.13 CDJ45583.1 - 0.038 12.7 5.4 0.044 12.5 5.4 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV Kelch_2 PF07646.15 CDJ45584.1 - 0.00052 19.9 2.7 0.54 10.3 0.8 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 CDJ45584.1 - 0.062 13.3 0.0 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Kelch motif DUF3602 PF12223.8 CDJ45584.1 - 0.24 12.0 0.4 0.24 12.0 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3602) SR-25 PF10500.9 CDJ45584.1 - 5.4 6.6 14.9 4 7.0 4.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ45584.1 - 7.3 7.0 20.0 0.15 12.4 1.5 3.1 2 1 1 3 3 3 0 Early growth response N-terminal domain Linocin_M18 PF04454.12 CDJ45586.1 - 0.39 10.0 1.8 0.55 9.5 1.8 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase MFS_1 PF07690.16 CDJ45588.1 - 0.001 18.1 6.4 0.001 18.1 6.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_34 PF11312.8 CDJ45588.1 - 0.017 14.4 0.3 0.024 13.9 0.3 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase MFS_2 PF13347.6 CDJ45588.1 - 0.053 12.1 8.2 0.082 11.4 8.2 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein Ribosomal_60s PF00428.19 CDJ45588.1 - 0.56 10.8 24.8 0.79 10.3 6.1 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein EF-hand_1 PF00036.32 CDJ45589.1 - 3e-15 54.6 11.8 1.9e-05 23.9 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CDJ45589.1 - 7.6e-15 53.5 9.6 1.5e-05 24.5 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 CDJ45589.1 - 3.6e-12 46.6 24.8 1e-06 29.1 0.6 3.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CDJ45589.1 - 1.7e-09 36.7 13.2 0.00045 19.6 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CDJ45589.1 - 3.2e-05 23.7 6.5 0.009 15.8 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair Cys_box PF17869.1 CDJ45589.1 - 0.064 13.4 3.2 0.23 11.6 0.7 2.4 2 0 0 2 2 2 0 Anosmin cysteine rich domain SPARC_Ca_bdg PF10591.9 CDJ45589.1 - 0.98 9.8 6.2 1.2 9.5 0.3 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TFIIA PF03153.13 CDJ45591.1 - 0.00046 20.3 46.0 0.00057 20.0 46.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ45591.1 - 0.014 14.0 28.1 0.018 13.6 28.1 1.1 1 0 0 1 1 1 0 Macoilin family GAGA_bind PF06217.12 CDJ45591.1 - 0.15 12.4 17.6 0.22 11.8 17.6 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Asp-B-Hydro_N PF05279.11 CDJ45591.1 - 0.2 11.7 21.3 0.25 11.4 21.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PAT1 PF09770.9 CDJ45591.1 - 0.78 7.9 34.5 0.91 7.7 34.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIF_alpha PF05793.12 CDJ45591.1 - 1.2 7.6 35.7 1.6 7.2 35.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) VIR_N PF15912.5 CDJ45591.1 - 2.2 7.8 17.4 3 7.4 17.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal GREB1 PF15782.5 CDJ45591.1 - 4.6 4.2 32.3 6.2 3.8 32.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MMR1 PF08505.10 CDJ45591.1 - 4.6 7.5 36.8 7.4 6.8 36.8 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Nucleo_P87 PF07267.11 CDJ45591.1 - 5.2 5.8 20.1 6.1 5.6 20.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PRP38 PF03371.15 CDJ45593.1 - 2.3e-49 167.6 0.0 3.5e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 PRP38 family Ribosomal_S6 PF01250.17 CDJ45595.1 - 5.2e-10 39.5 0.0 6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Activator_LAG-3 PF11498.8 CDJ45596.1 - 0.13 11.2 9.2 0.21 10.5 9.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Apt1 PF10351.9 CDJ45597.1 - 1.8 7.3 13.3 0.11 11.3 5.5 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF755 PF05501.11 CDJ45597.1 - 7.8 6.8 36.9 0.039 14.2 5.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF755) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria-tenella-ETH001/GCA_000499545.1_ETH001_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria-tenella-ETH001/GCA_000499545.1_ETH001_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria-tenella-ETH001/GCA_000499545.1_ETH001_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria-tenella-ETH001/GCA_000499545.1_ETH001_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 01:36:37 2019 # [ok]