# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF3870 PF12986.2 EAK87289.1 - 0.03 14.5 0.3 0.03 14.5 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3870) DUF3814 PF12769.2 EAK87290.1 - 0.078 13.1 0.1 9.9 6.4 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3814) Chlam_OMP3 PF03503.8 EAK87290.1 - 1.9 8.7 11.1 5.8 7.2 0.3 3.1 3 0 0 3 3 3 0 Chlamydia cysteine-rich outer membrane protein 3 zf-DHHC PF01529.15 EAK87291.1 - 5.3 6.4 10.5 0.94 8.8 1.9 3.0 3 1 0 3 3 3 0 DHHC palmitoyltransferase GATase PF00117.23 EAK87292.1 - 6e-25 87.8 0.5 2.6e-24 85.7 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EAK87292.1 - 3.1e-20 71.6 0.0 5.8e-19 67.5 0.0 2.7 1 1 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EAK87292.1 - 6.5e-11 41.5 0.1 4.8e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.16 EAK87292.1 - 0.00021 20.8 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase Spore_YhcN_YlaJ PF09580.5 EAK87292.1 - 0.011 15.8 16.6 0.43 10.6 0.8 2.3 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) QueC PF06508.8 EAK87292.1 - 0.012 14.9 0.0 0.046 12.9 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Peptidase_C26 PF07722.8 EAK87292.1 - 0.012 15.0 0.2 0.064 12.6 0.1 2.3 1 1 1 2 2 2 0 Peptidase C26 ThiI PF02568.9 EAK87292.1 - 0.044 13.2 0.1 0.68 9.3 0.0 2.2 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) AsnA PF03590.10 EAK87293.1 - 1.2e-61 208.2 4.9 2.2e-61 207.4 3.4 1.3 1 0 0 1 1 1 1 Aspartate-ammonia ligase Choline_kin_N PF04428.9 EAK87293.1 - 0.00089 18.6 0.1 0.085 12.3 0.0 2.9 3 0 0 3 3 3 1 Choline kinase N terminus tRNA-synt_2 PF00152.15 EAK87293.1 - 0.0044 15.8 0.2 0.0067 15.2 0.1 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) LRR_adjacent PF08191.6 EAK87293.1 - 0.12 12.0 0.5 20 5.0 0.1 2.5 2 0 0 2 2 2 0 LRR adjacent PALP PF00291.20 EAK87294.1 - 1.8e-39 135.8 0.1 2.4e-39 135.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Nop14 PF04147.7 EAK87295.1 - 0.11 10.4 18.6 0.11 10.4 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family ETRAMP PF09716.5 EAK87295.1 - 2.4 8.1 7.5 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF1510 PF07423.6 EAK87295.1 - 6.9 5.9 23.6 85 2.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Nucleoplasmin PF03066.10 EAK87296.1 - 0.0046 16.4 7.8 0.0063 16.0 5.4 1.2 1 0 0 1 1 1 1 Nucleoplasmin Myc_N PF01056.13 EAK87296.1 - 0.0073 15.5 8.0 0.012 14.7 5.5 1.4 1 0 0 1 1 1 1 Myc amino-terminal region CDC45 PF02724.9 EAK87296.1 - 0.011 13.8 11.1 0.012 13.6 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EAK87296.1 - 0.016 13.7 14.5 0.02 13.3 10.0 1.1 1 0 0 1 1 1 0 Daxx Family Herpes_LMP1 PF05297.6 EAK87296.1 - 0.1 11.5 5.4 0.15 10.9 3.8 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Paf1 PF03985.8 EAK87296.1 - 0.13 10.9 15.6 0.16 10.7 10.8 1.1 1 0 0 1 1 1 0 Paf1 RNase_H2-Ydr279 PF09468.5 EAK87296.1 - 0.18 10.9 8.3 0.26 10.4 5.7 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Spt5_N PF11942.3 EAK87296.1 - 0.19 12.3 17.5 0.3 11.7 12.2 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal GAGA_bind PF06217.7 EAK87296.1 - 0.43 10.4 8.9 0.62 9.9 6.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3381 PF11861.3 EAK87296.1 - 0.76 9.2 18.1 1.2 8.6 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Hid1 PF12722.2 EAK87296.1 - 0.85 7.2 6.6 0.86 7.2 4.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GRP PF07172.6 EAK87296.1 - 0.86 10.1 18.7 0.29 11.6 2.2 2.5 2 1 0 2 2 2 0 Glycine rich protein family Nop14 PF04147.7 EAK87296.1 - 1.2 6.9 17.2 1.4 6.7 11.9 1.0 1 0 0 1 1 1 0 Nop14-like family Herpes_DNAp_acc PF04929.7 EAK87296.1 - 1.5 7.7 10.4 2 7.2 7.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Pox_Ag35 PF03286.9 EAK87296.1 - 1.8 8.0 12.4 2.9 7.3 8.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein G-alpha PF00503.15 EAK87296.1 - 2 7.0 11.0 3.1 6.3 7.7 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Raftlin PF15250.1 EAK87296.1 - 2.1 6.7 7.6 2.4 6.5 5.2 1.2 1 0 0 1 1 1 0 Raftlin YqfQ PF14181.1 EAK87296.1 - 2.2 8.2 17.2 0.78 9.7 9.3 1.9 2 0 0 2 2 2 0 YqfQ-like protein VID27 PF08553.5 EAK87296.1 - 2.5 6.1 15.1 3.3 5.8 10.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein NOA36 PF06524.7 EAK87296.1 - 2.7 7.1 11.6 3.6 6.7 8.0 1.2 1 0 0 1 1 1 0 NOA36 protein Prog_receptor PF02161.10 EAK87296.1 - 3.1 6.5 6.7 4 6.1 4.7 1.2 1 0 0 1 1 1 0 Progesterone receptor DUF1510 PF07423.6 EAK87296.1 - 3.4 6.9 18.9 5.3 6.3 13.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4175 PF13779.1 EAK87296.1 - 3.7 5.1 12.0 4.6 4.8 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) GRP PF07172.6 EAK87297.1 - 0.0012 19.2 0.3 0.0012 19.2 0.2 2.3 2 0 0 2 2 2 1 Glycine rich protein family Merozoite_SPAM PF07133.6 EAK87297.1 - 0.02 14.8 12.6 0.032 14.1 8.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF3381 PF11861.3 EAK87297.1 - 0.039 13.4 9.3 0.067 12.7 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PT PF04886.7 EAK87297.1 - 0.18 11.1 1.3 0.27 10.5 0.9 1.2 1 0 0 1 1 1 0 PT repeat DUF2763 PF10961.3 EAK87297.1 - 0.2 12.0 0.2 0.2 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Nop14 PF04147.7 EAK87297.1 - 0.22 9.4 16.7 0.25 9.2 11.5 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 EAK87297.1 - 0.44 8.1 3.0 0.46 8.0 2.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 EAK87297.1 - 0.95 7.4 16.8 1.3 6.9 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EAK87297.1 - 1.5 8.2 12.7 2.4 7.6 8.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF1510 PF07423.6 EAK87297.1 - 4.5 6.5 15.4 2.9 7.1 8.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Tom37_C PF11801.3 EAK87297.1 - 6.7 6.5 6.3 12 5.6 4.4 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain Zip PF02535.17 EAK87298.1 - 0.00014 20.9 1.4 0.00014 20.9 1.0 2.1 2 0 0 2 2 2 1 ZIP Zinc transporter Nop14 PF04147.7 EAK87298.1 - 0.002 16.1 20.2 0.0023 15.9 14.0 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 EAK87298.1 - 0.014 13.8 20.0 0.02 13.4 13.9 1.2 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 EAK87298.1 - 0.05 12.8 15.5 0.06 12.5 10.7 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PT PF04886.7 EAK87298.1 - 0.13 11.5 1.1 0.2 10.9 0.8 1.2 1 0 0 1 1 1 0 PT repeat YL1 PF05764.8 EAK87298.1 - 0.43 10.1 24.4 0.78 9.3 16.9 1.5 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.5 EAK87298.1 - 0.63 9.0 21.4 0.76 8.7 14.8 1.2 1 0 0 1 1 1 0 BUD22 DUF1510 PF07423.6 EAK87298.1 - 0.66 9.3 18.1 1.4 8.2 12.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EAK87298.1 - 1.2 7.0 24.4 1.7 6.6 16.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.6 EAK87298.1 - 1.5 8.7 23.7 2.4 8.0 16.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Daxx PF03344.10 EAK87300.1 - 0.0099 14.4 15.0 0.011 14.2 10.4 1.1 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 EAK87300.1 - 0.028 12.3 19.3 0.033 12.1 13.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EAK87300.1 - 0.054 12.7 19.1 0.073 12.3 13.2 1.3 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.7 EAK87300.1 - 0.14 11.8 20.3 0.19 11.4 14.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EAK87300.1 - 0.81 7.6 21.1 1 7.2 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 EAK87300.1 - 1.1 8.8 17.8 1.6 8.2 12.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Ebola_NP PF05505.7 EAK87300.1 - 1.2 7.0 12.3 1.6 6.7 8.5 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein TFIIF_alpha PF05793.7 EAK87300.1 - 1.4 7.2 25.2 1.6 6.9 17.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CobT PF06213.7 EAK87300.1 - 2.6 7.1 19.6 3.6 6.6 13.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nucleo_P87 PF07267.6 EAK87300.1 - 3.1 6.3 11.4 3.6 6.1 7.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1510 PF07423.6 EAK87300.1 - 3.2 7.0 16.1 4.7 6.5 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC27 PF09507.5 EAK87300.1 - 7.4 5.6 20.9 9.2 5.3 14.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Daxx PF03344.10 EAK87301.1 - 0.0046 15.5 14.2 0.0053 15.3 9.8 1.1 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 EAK87301.1 - 0.038 11.9 15.0 0.044 11.7 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 EAK87301.1 - 2.6 7.3 16.5 3.5 6.9 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DSHCT PF08148.7 EAK87306.1 - 2e-32 111.8 0.1 2e-32 111.8 0.1 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EAK87306.1 - 1.8e-21 76.3 0.1 2.2e-20 72.8 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK87306.1 - 1.1e-06 28.4 0.0 4.4e-06 26.4 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sec20 PF03908.8 EAK87308.1 - 4.5e-06 26.2 1.5 8.5e-06 25.3 1.0 1.5 1 0 0 1 1 1 1 Sec20 V-SNARE_C PF12352.3 EAK87308.1 - 4e-05 23.6 0.7 6.4e-05 22.9 0.5 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus eIF3_p135 PF12807.2 EAK87309.1 - 2.1e-10 40.7 0.1 1e-09 38.5 0.0 2.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 PPP4R2 PF09184.6 EAK87310.1 - 4.8e-08 32.8 2.6 4.8e-08 32.8 1.8 1.9 1 1 0 1 1 1 1 PPP4R2 XPA_N PF01286.13 EAK87310.1 - 0.19 11.4 1.7 0.46 10.1 1.2 1.6 1 0 0 1 1 1 0 XPA protein N-terminal zf-C2H2 PF00096.21 EAK87310.1 - 6.4 7.3 6.3 1.9 9.0 0.3 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type TRAPPC10 PF12584.3 EAK87312.1 - 5.8e-05 22.6 0.1 0.00096 18.6 0.0 2.8 3 0 0 3 3 3 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.2 EAK87312.1 - 0.012 15.4 0.0 0.035 13.8 0.0 1.8 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking TPR_10 PF13374.1 EAK87312.1 - 0.24 11.4 0.1 0.54 10.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Spindle_Spc25 PF08234.7 EAK87313.1 - 1.3e-17 63.5 1.8 1.3e-17 63.5 1.3 2.2 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Apolipoprotein PF01442.13 EAK87313.1 - 0.027 13.9 6.2 0.15 11.5 4.3 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoO PF09769.4 EAK87313.1 - 0.13 11.9 1.9 0.23 11.1 1.3 1.3 1 0 0 1 1 1 0 Apolipoprotein O Hydantoinase_B PF02538.9 EAK87313.1 - 0.25 9.5 1.8 0.32 9.1 1.2 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase CorA PF01544.13 EAK87313.1 - 0.8 8.6 6.1 1.3 8.0 4.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IncA PF04156.9 EAK87313.1 - 1.3 8.5 15.9 3.4 7.2 11.0 1.7 1 1 0 1 1 1 0 IncA protein DGCR6 PF07324.6 EAK87313.1 - 1.5 8.2 10.9 0.4 10.1 3.0 2.0 1 1 1 2 2 2 0 DiGeorge syndrome critical region 6 (DGCR6) protein SlyX PF04102.7 EAK87313.1 - 3.4 8.1 8.6 1.3 9.4 0.2 3.1 3 1 0 3 3 3 0 SlyX MMR_HSR1 PF01926.18 EAK87314.1 - 1.1e-18 67.3 0.0 2.2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EAK87314.1 - 1.4e-14 53.6 0.3 3.8e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.13 EAK87314.1 - 1.8e-12 46.8 0.0 3.5e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EAK87314.1 - 5.4e-06 26.9 0.0 2.2e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EAK87314.1 - 2.8e-05 24.0 0.1 0.013 15.3 0.0 2.3 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.5 EAK87314.1 - 0.0031 16.7 0.0 0.0056 15.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EAK87314.1 - 0.0041 16.3 0.2 0.11 11.7 0.0 2.4 1 1 1 2 2 2 1 ADP-ribosylation factor family AAA_28 PF13521.1 EAK87314.1 - 0.0049 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EAK87314.1 - 0.073 12.5 0.2 0.37 10.2 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MCM PF00493.18 EAK87314.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family zf-CCCH PF00642.19 EAK87315.1 - 5.1e-06 26.0 1.2 1e-05 25.0 0.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WD40 PF00400.27 EAK87315.1 - 0.00028 20.6 2.1 1 9.3 0.1 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF947 PF06102.7 EAK87316.1 - 1.2e-43 148.8 26.4 1.2e-43 148.8 18.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF947) PglZ PF08665.7 EAK87316.1 - 3.3 7.3 8.2 0.58 9.8 2.3 2.1 2 1 0 2 2 2 0 PglZ domain DUF904 PF06005.7 EAK87317.1 - 0.042 14.1 22.2 2.8 8.2 3.1 3.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) HALZ PF02183.13 EAK87317.1 - 0.24 11.1 10.8 0.074 12.7 1.4 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper FliS PF02561.9 EAK87317.1 - 1 9.2 7.8 0.072 12.9 0.3 2.9 3 1 0 3 3 3 0 Flagellar protein FliS Prefoldin_2 PF01920.15 EAK87317.1 - 1.1 9.0 14.2 0.57 9.9 7.3 2.5 3 0 0 3 3 3 0 Prefoldin subunit bZIP_1 PF00170.16 EAK87317.1 - 2.4 8.1 13.5 6.7 6.7 3.0 2.7 2 0 0 2 2 2 0 bZIP transcription factor Ribonuclease_3 PF00636.21 EAK87318.1 - 0.054 13.9 0.0 0.26 11.7 0.0 2.2 1 1 0 1 1 1 0 Ribonuclease III domain Agglutinin PF07468.6 EAK87318.1 - 0.057 13.3 0.2 2.8 7.9 0.0 2.7 2 0 0 2 2 2 0 Agglutinin Asn_synthase PF00733.16 EAK87320.1 - 3.3e-12 46.4 0.0 2.5e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 Asparagine synthase ATP_bind_3 PF01171.15 EAK87320.1 - 0.062 12.7 0.6 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 PP-loop family DUF3452 PF11934.3 EAK87321.1 - 1 8.7 7.2 1.3 8.3 0.0 3.7 2 2 1 4 4 4 0 Domain of unknown function (DUF3452) DUF1777 PF08648.7 EAK87323.1 - 0.0034 17.1 29.6 0.0034 17.1 20.5 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF1777) Toxin_10 PF05431.6 EAK87323.1 - 0.08 12.5 6.4 1.2 8.7 0.8 2.9 2 0 0 2 2 2 0 Insecticidal Crystal Toxin, P42 ArfGap PF01412.13 EAK87324.1 - 9.5e-05 22.1 1.2 0.00019 21.1 0.8 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF2318 PF10080.4 EAK87324.1 - 0.41 10.4 3.0 0.37 10.5 0.2 2.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) DUF676 PF05057.9 EAK87326.1 - 1.1e-41 142.4 0.0 2.4e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.3 EAK87326.1 - 2e-18 66.2 0.8 8e-18 64.2 0.6 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3657) PGAP1 PF07819.8 EAK87326.1 - 7.7e-05 22.3 0.2 0.0017 18.0 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EAK87326.1 - 0.0069 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAK87326.1 - 0.033 14.0 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3265 PF11665.3 EAK87327.1 - 0.067 13.0 0.5 0.067 13.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3265) AdoHcyase PF05221.12 EAK87329.1 - 2.5e-111 370.9 0.2 2.9e-111 370.7 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EAK87329.1 - 7e-70 234.0 2.2 1.1e-69 233.4 1.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EAK87329.1 - 1.8e-10 40.2 0.1 3.4e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EAK87329.1 - 1.3e-06 27.8 0.3 2.3e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EAK87329.1 - 3e-05 23.9 0.9 0.00011 22.1 0.6 1.9 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.1 EAK87329.1 - 0.00014 22.0 0.1 0.00036 20.7 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EAK87329.1 - 0.00035 20.6 1.1 0.00099 19.2 0.7 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 EAK87329.1 - 0.0016 17.5 1.2 0.0068 15.5 0.8 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 EAK87329.1 - 0.018 15.4 0.3 0.037 14.4 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Malic_M PF03949.10 EAK87329.1 - 0.053 13.0 3.2 0.091 12.3 0.1 2.1 1 1 1 2 2 2 0 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.16 EAK87329.1 - 0.18 11.3 1.2 0.53 9.8 0.8 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 EAK87329.1 - 0.21 11.1 1.7 0.66 9.5 1.2 1.8 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Na_H_Exchanger PF00999.16 EAK87330.1 - 5e-47 160.2 37.0 6.9e-47 159.7 25.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Sporozoite_P67 PF05642.6 EAK87333.1 - 0.47 8.2 18.6 0.49 8.1 12.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 EAK87333.1 - 0.53 8.1 3.8 0.56 8.0 2.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF572 PF04502.8 EAK87333.1 - 0.69 9.0 5.6 0.82 8.8 3.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PBD PF00786.23 EAK87333.1 - 0.83 10.1 0.2 0.83 10.1 0.1 2.8 2 1 0 2 2 2 0 P21-Rho-binding domain DUF605 PF04652.11 EAK87333.1 - 1.3 8.3 14.0 1.5 8.1 9.7 1.1 1 0 0 1 1 1 0 Vta1 like Apt1 PF10351.4 EAK87333.1 - 2.2 7.0 21.4 2.5 6.8 14.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAP1 PF08601.5 EAK87333.1 - 5.8 6.4 24.5 6.7 6.2 17.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Peptidase_M48 PF01435.13 EAK87335.1 - 7.5e-29 100.9 0.0 1.3e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EAK87335.1 - 0.0096 14.9 0.5 0.019 13.9 0.4 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF908 PF06012.7 EAK87336.1 - 0.037 13.3 0.9 0.063 12.5 0.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MS_channel PF00924.13 EAK87337.1 - 3e-15 56.0 3.6 5.8e-15 55.1 2.5 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF4318 PF14201.1 EAK87337.1 - 0.031 14.1 0.2 0.084 12.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4318) Malectin PF11721.3 EAK87338.1 - 2e-35 122.1 0.2 2.5e-35 121.7 0.1 1.1 1 0 0 1 1 1 1 Di-glucose binding within endoplasmic reticulum Na_H_Exchanger PF00999.16 EAK87339.1 - 7.6e-51 172.8 33.6 1e-50 172.3 23.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Thioredoxin PF00085.15 EAK87340.1 - 3.3e-56 187.3 0.1 9.5e-28 95.9 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EAK87340.1 - 4.3e-22 78.8 6.0 2.2e-14 53.6 1.0 4.0 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EAK87340.1 - 4e-13 49.5 3.4 3e-08 33.8 0.1 4.6 3 3 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EAK87340.1 - 1.2e-10 41.3 0.3 0.0028 17.7 0.0 5.5 4 2 2 6 6 6 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EAK87340.1 - 1.8e-10 40.6 0.0 0.0014 18.6 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 EAK87340.1 - 1e-07 31.6 0.7 0.02 14.5 0.0 3.1 3 0 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.12 EAK87340.1 - 7.7e-06 24.9 0.1 1.1e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Calsequestrin Redoxin PF08534.5 EAK87340.1 - 0.00017 21.1 0.0 0.25 10.8 0.0 2.5 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EAK87340.1 - 0.0027 17.2 0.0 1.3 8.6 0.0 3.2 3 1 1 4 4 4 1 Thioredoxin Thioredoxin_4 PF13462.1 EAK87340.1 - 0.013 15.5 1.5 9.1 6.2 0.0 3.6 3 0 0 3 3 3 0 Thioredoxin Thioredoxin_5 PF13743.1 EAK87340.1 - 0.15 11.5 0.4 22 4.5 0.1 3.3 3 0 0 3 3 3 0 Thioredoxin GLTSCR1 PF15249.1 EAK87341.1 - 3.4e-05 23.8 0.3 6.4e-05 23.0 0.2 1.6 1 1 0 1 1 1 1 Glioma tumor suppressor candidate region DUF761 PF05553.6 EAK87342.1 - 0.16 11.3 0.5 0.31 10.4 0.4 1.5 1 0 0 1 1 1 0 Cotton fibre expressed protein PH PF00169.24 EAK87344.1 - 8.5e-06 25.9 1.4 8.5e-06 25.9 0.9 3.4 4 1 0 4 4 4 1 PH domain cEGF PF12662.2 EAK87345.1 - 0.018 14.6 11.7 0.65 9.6 0.1 4.7 3 1 0 3 3 3 0 Complement Clr-like EGF-like CPW_WPC PF09717.5 EAK87345.1 - 0.074 13.6 8.9 6.9 7.3 0.1 5.1 2 2 3 5 5 5 0 Plasmodium falciparum domain of unknown function (CPW_WPC) CC PF04942.9 EAK87345.1 - 0.081 12.8 32.2 0.11 12.3 0.1 6.9 7 0 0 7 7 7 0 CC domain zf-RING_6 PF14835.1 EAK87345.1 - 0.14 11.9 1.6 0.48 10.2 0.2 2.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Tme5_EGF_like PF09064.5 EAK87345.1 - 0.37 10.4 10.9 8.2 6.1 0.0 4.8 4 1 1 5 5 5 0 Thrombomodulin like fifth domain, EGF-like Antistasin PF02822.9 EAK87345.1 - 0.46 10.8 12.7 5 7.5 0.0 5.7 4 1 1 5 5 5 0 Antistasin family Otopetrin PF03189.8 EAK87346.1 - 0.0059 15.6 0.1 0.0059 15.6 0.0 1.9 2 0 0 2 2 2 1 Otopetrin G-patch_2 PF12656.2 EAK87347.1 - 2e-15 56.4 0.2 6.3e-15 54.7 0.0 1.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site G-patch PF01585.18 EAK87347.1 - 0.063 13.0 0.2 0.98 9.2 0.0 2.3 2 0 0 2 2 2 0 G-patch domain APG6 PF04111.7 EAK87348.1 - 2.9e-39 134.9 10.6 1.5e-38 132.6 7.3 1.9 1 1 0 1 1 1 1 Autophagy protein Apg6 DAGAT PF03982.8 EAK87349.1 - 3.5e-19 68.6 0.2 5.6e-19 67.9 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase PrgI PF12666.2 EAK87349.1 - 0.72 10.0 5.3 5.3 7.2 1.2 2.9 3 0 0 3 3 3 0 PrgI family protein XhlA PF10779.4 EAK87351.1 - 0.068 13.0 3.4 0.11 12.4 2.3 1.3 1 0 0 1 1 1 0 Haemolysin XhlA End3 PF12761.2 EAK87351.1 - 0.08 12.5 0.7 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 ABC2_membrane_3 PF12698.2 EAK87351.1 - 2.3 7.1 7.3 2.7 6.9 5.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Mg_trans_NIPA PF05653.9 EAK87353.1 - 5.8e-14 51.7 21.2 8.8e-10 38.0 3.0 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EAK87353.1 - 1.6e-05 24.9 7.2 1.6e-05 24.9 5.0 3.3 4 0 0 4 4 4 2 EamA-like transporter family RAB3GAP2_N PF14655.1 EAK87355.1 - 0.015 14.2 0.8 1.4 7.8 0.1 2.0 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus IMPDH PF00478.20 EAK87356.1 - 7.8e-142 472.3 4.2 8.8e-142 472.1 2.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EAK87356.1 - 5.1e-11 42.0 10.7 6.7e-10 38.3 2.9 2.7 2 1 1 3 3 3 2 FMN-dependent dehydrogenase NMO PF03060.10 EAK87356.1 - 1.7e-09 37.3 10.0 1.1e-08 34.6 6.9 2.6 1 1 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EAK87356.1 - 2e-07 30.5 6.1 3.9e-07 29.5 4.3 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein Glu_synthase PF01645.12 EAK87356.1 - 9.9e-05 21.4 4.9 9.9e-05 21.4 3.4 1.7 1 1 1 2 2 2 1 Conserved region in glutamate synthase Dus PF01207.12 EAK87356.1 - 0.0012 17.6 2.0 0.052 12.3 0.0 2.7 3 0 0 3 3 3 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 EAK87356.1 - 0.0016 17.6 0.7 0.0016 17.6 0.5 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG EAL PF00563.15 EAK87356.1 - 0.011 15.1 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 EAL domain QRPTase_C PF01729.14 EAK87356.1 - 0.013 15.0 0.6 0.033 13.7 0.4 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain PEP_mutase PF13714.1 EAK87356.1 - 0.058 12.6 0.1 0.12 11.5 0.1 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Response_reg PF00072.19 EAK87356.1 - 0.061 13.3 1.1 0.33 10.9 0.1 2.4 3 0 0 3 3 3 0 Response regulator receiver domain TMP-TENI PF02581.12 EAK87356.1 - 0.076 12.1 4.1 3.7 6.6 0.3 2.8 1 1 2 3 3 3 0 Thiamine monophosphate synthase/TENI DHO_dh PF01180.16 EAK87356.1 - 0.27 10.1 7.9 0.87 8.4 5.5 2.0 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase PcrB PF01884.12 EAK87356.1 - 0.92 8.7 11.2 3.4 6.8 0.2 3.3 2 1 1 3 3 3 0 PcrB family DeoC PF01791.4 EAK87356.1 - 1.1 8.5 5.1 3 7.0 2.1 2.1 1 1 1 2 2 2 0 DeoC/LacD family aldolase Hist_deacetyl PF00850.14 EAK87357.1 - 2.7e-77 260.1 0.0 3.8e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain LRR_4 PF12799.2 EAK87358.1 - 2.6e-26 90.7 52.2 2.6e-07 30.0 7.3 7.0 5 1 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAK87358.1 - 5.2e-18 64.5 38.6 4.7e-07 29.4 6.3 5.9 4 2 2 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EAK87358.1 - 6.5e-10 37.6 41.2 0.48 10.6 1.7 9.9 10 1 0 10 10 10 7 Leucine Rich Repeat LRR_7 PF13504.1 EAK87358.1 - 1.7e-09 36.3 17.3 2.9 8.4 0.0 9.3 10 1 0 10 10 10 2 Leucine rich repeat LRR_6 PF13516.1 EAK87358.1 - 0.00082 19.1 37.1 1.2 9.4 2.3 9.5 9 1 1 10 10 10 3 Leucine Rich repeat LRR_9 PF14580.1 EAK87358.1 - 0.0025 17.4 12.6 1.2 8.6 1.4 3.4 1 1 2 3 3 3 3 Leucine-rich repeat MCM PF00493.18 EAK87359.1 - 5.7e-134 446.0 0.1 5.7e-134 446.0 0.1 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EAK87359.1 - 3.6e-11 43.5 1.6 1.2e-09 38.6 0.0 3.0 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EAK87359.1 - 5.5e-06 25.6 0.0 1.8e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EAK87359.1 - 1.8e-05 24.4 0.0 4.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps36_ESCRT-II PF11605.3 EAK87360.1 - 2.5e-05 23.9 0.0 5.6e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.1 EAK87360.1 - 0.019 15.2 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain SR-25 PF10500.4 EAK87361.1 - 0.11 11.9 10.1 0.15 11.5 7.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.5 EAK87361.1 - 0.23 10.4 3.5 0.29 10.1 2.4 1.1 1 0 0 1 1 1 0 BUD22 CAF-1_p150 PF11600.3 EAK87361.1 - 1.6 8.0 6.3 2.8 7.2 4.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Secretin_N PF03958.12 EAK87364.1 - 0.11 12.6 3.0 8.5 6.6 1.2 2.3 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain SR-25 PF10500.4 EAK87364.1 - 0.49 9.8 13.9 0.74 9.2 9.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pheromone PF08015.6 EAK87364.1 - 2.5 8.9 11.4 2.1 9.2 1.2 2.5 3 0 0 3 3 3 0 Fungal mating-type pheromone Arm PF00514.18 EAK87368.1 - 2.7e-11 42.8 0.2 0.0089 15.8 0.0 4.7 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat WAPL PF07814.8 EAK87368.1 - 0.0082 14.9 0.0 0.033 12.9 0.0 1.8 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin eIF2A PF08662.6 EAK87369.1 - 2.4e-34 118.7 5.6 9.6e-28 97.2 2.1 3.8 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EAK87369.1 - 1.6e-05 24.6 5.4 7.5 6.6 0.0 6.3 6 1 0 6 6 6 2 WD domain, G-beta repeat RRM_5 PF13893.1 EAK87369.1 - 0.11 12.3 0.1 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleoside_tran PF01733.13 EAK87371.1 - 5.9e-24 84.7 11.4 5.9e-24 84.7 7.9 1.5 2 0 0 2 2 2 1 Nucleoside transporter Kelch_3 PF13415.1 EAK87372.1 - 1.9e-15 56.5 2.0 2.9e-07 30.4 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EAK87372.1 - 8.5e-15 54.2 7.1 0.00015 21.4 0.0 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EAK87372.1 - 1.7e-09 37.3 6.3 0.00017 21.6 0.1 6.0 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.1 EAK87372.1 - 2e-09 37.2 0.0 0.0056 16.5 0.0 4.0 4 0 0 4 4 4 2 Kelch motif HATPase_c_3 PF13589.1 EAK87372.1 - 4.9e-09 35.9 2.6 1.2e-08 34.6 0.0 2.7 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_1 PF01344.20 EAK87372.1 - 1.2e-05 24.7 0.9 0.00061 19.2 0.0 3.6 4 0 0 4 4 4 1 Kelch motif HATPase_c PF02518.21 EAK87372.1 - 0.00087 18.9 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_2 PF07646.10 EAK87372.1 - 0.14 11.9 5.0 13 5.7 0.0 4.9 6 0 0 6 6 6 0 Kelch motif Ribosomal_L15e PF00827.12 EAK87374.1 - 8.1e-91 302.7 8.8 9.4e-91 302.5 6.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 eIF-3_zeta PF05091.7 EAK87375.1 - 1.5e-164 548.4 0.8 1.7e-164 548.3 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Serinc PF03348.10 EAK87375.1 - 0.058 12.1 0.2 0.09 11.4 0.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) His_binding PF02098.11 EAK87376.1 - 0.036 13.8 1.1 0.036 13.8 0.8 1.9 2 0 0 2 2 2 0 Tick histamine binding protein V-ATPase_G PF03179.10 EAK87377.1 - 2e-25 89.1 8.1 2.3e-25 88.9 5.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Miro PF08477.8 EAK87377.1 - 0.0001 22.8 0.5 0.00013 22.4 0.3 1.2 1 0 0 1 1 1 1 Miro-like protein DUF3523 PF12037.3 EAK87377.1 - 0.081 11.8 6.0 0.094 11.6 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) ABC_tran PF00005.22 EAK87377.1 - 0.082 13.1 0.2 0.095 13.0 0.1 1.2 1 0 0 1 1 1 0 ABC transporter Vps16_C PF04840.7 EAK87377.1 - 0.13 11.1 3.0 0.16 10.8 1.9 1.3 1 1 0 1 1 1 0 Vps16, C-terminal region MIS13 PF08202.6 EAK87377.1 - 0.17 10.9 4.9 0.21 10.6 3.4 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family DUF3552 PF12072.3 EAK87377.1 - 0.53 9.4 11.6 1.1 8.4 8.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) ATP-synt_B PF00430.13 EAK87377.1 - 5.5 6.7 11.9 3.4 7.4 5.5 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Syja_N PF02383.13 EAK87379.1 - 5e-87 291.6 0.3 2e-86 289.6 0.2 2.1 1 1 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EAK87379.1 - 2.4e-13 50.5 0.0 4.5e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YEATS PF03366.11 EAK87380.1 - 1.2e-30 105.0 0.1 1.2e-30 105.0 0.1 1.9 2 0 0 2 2 2 1 YEATS family DUF3953 PF13129.1 EAK87380.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) Mito_fiss_reg PF05308.6 EAK87380.1 - 0.55 9.5 9.0 0.024 14.0 2.1 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator NAD_Gly3P_dh_N PF01210.18 EAK87381.1 - 1.3e-43 148.4 0.0 1.9e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EAK87381.1 - 8.9e-32 109.8 0.0 1.3e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EAK87381.1 - 0.07 13.5 0.2 0.51 10.8 0.1 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Got1 PF04178.7 EAK87382.1 - 9.8e-20 70.8 14.3 1.1e-19 70.7 9.9 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.8 EAK87382.1 - 0.0043 16.9 16.7 0.011 15.7 5.9 2.2 1 1 1 2 2 2 1 Short repeat of unknown function (DUF308) DUF973 PF06157.6 EAK87382.1 - 0.011 14.7 10.4 0.013 14.4 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF1129 PF06570.6 EAK87382.1 - 0.063 12.5 6.9 0.081 12.2 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) COPI_assoc PF08507.5 EAK87382.1 - 4.7 6.8 16.0 4.3 7.0 3.8 2.2 1 1 1 2 2 2 0 COPI associated protein BCAS2 PF05700.6 EAK87383.1 - 4.5e-08 32.8 17.5 8.5e-07 28.6 9.1 2.1 1 1 1 2 2 2 2 Breast carcinoma amplified sequence 2 (BCAS2) Baculo_VP91_N PF08475.5 EAK87383.1 - 0.092 12.0 1.0 0.15 11.3 0.7 1.4 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal B5 PF03484.10 EAK87383.1 - 0.54 10.1 2.5 6.7 6.6 1.8 2.6 1 1 0 1 1 1 0 tRNA synthetase B5 domain GNT-I PF03071.10 EAK87383.1 - 0.59 8.6 5.5 0.53 8.7 3.1 1.4 1 1 0 1 1 1 0 GNT-I family DUF2203 PF09969.4 EAK87383.1 - 6 7.1 11.6 11 6.2 0.7 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Brix PF04427.13 EAK87384.1 - 1.3e-42 145.6 0.8 2.1e-42 144.9 0.5 1.3 1 0 0 1 1 1 1 Brix domain Borrelia_P83 PF05262.6 EAK87384.1 - 1.4 7.0 16.4 1.9 6.6 11.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein MCPVI PF02993.9 EAK87384.1 - 2.6 8.1 6.1 4.3 7.4 4.2 1.3 1 0 0 1 1 1 0 Minor capsid protein VI SOBP PF15279.1 EAK87384.1 - 7 6.9 6.4 10 6.4 4.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein R3H-assoc PF13902.1 EAK87385.1 - 0.00073 19.5 0.2 0.0036 17.2 0.1 2.2 1 1 0 1 1 1 1 R3H-associated N-terminal domain HTH_19 PF12844.2 EAK87385.1 - 0.0027 17.7 1.1 0.93 9.5 0.0 3.3 3 0 0 3 3 3 2 Helix-turn-helix domain R3H PF01424.17 EAK87385.1 - 0.0037 16.9 0.0 0.02 14.5 0.0 2.1 2 0 0 2 2 2 1 R3H domain Ribosomal_60s PF00428.14 EAK87386.1 - 1.2e-23 83.2 2.0 1.4e-23 83.0 1.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein ABC_tran PF00005.22 EAK87388.1 - 4.6e-31 107.9 0.0 1.6e-15 57.6 0.0 3.1 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAK87388.1 - 6.1e-29 101.2 24.6 7.5e-21 74.7 3.7 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region MMR_HSR1 PF01926.18 EAK87388.1 - 4.2e-08 33.1 0.0 0.0024 17.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SE PF00437.15 EAK87388.1 - 1.1e-07 31.0 0.5 0.0079 15.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EAK87388.1 - 4.6e-07 29.5 0.0 0.0044 16.5 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 EAK87388.1 - 1.4e-06 28.4 0.0 0.00049 20.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EAK87388.1 - 1.6e-06 27.5 0.3 0.017 14.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EAK87388.1 - 2.1e-06 28.2 0.1 0.18 12.3 0.0 3.2 3 0 0 3 3 2 2 Miro-like protein AAA_17 PF13207.1 EAK87388.1 - 2.5e-06 28.3 0.0 0.069 13.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EAK87388.1 - 1.2e-05 24.9 0.2 0.13 11.7 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain Dynamin_N PF00350.18 EAK87388.1 - 1.7e-05 24.7 0.6 0.13 12.0 0.1 2.8 2 0 0 2 2 2 2 Dynamin family NACHT PF05729.7 EAK87388.1 - 3.7e-05 23.4 0.3 0.061 12.9 0.0 2.7 2 0 0 2 2 2 2 NACHT domain DUF87 PF01935.12 EAK87388.1 - 4e-05 23.5 2.8 0.0049 16.7 0.1 3.0 2 1 1 3 3 3 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EAK87388.1 - 7e-05 22.9 0.3 0.12 12.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 EAK87388.1 - 7.2e-05 22.0 0.5 0.0049 16.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EAK87388.1 - 0.00015 22.0 2.6 0.72 10.1 0.0 3.8 4 0 0 4 4 3 2 AAA domain Arch_ATPase PF01637.13 EAK87388.1 - 0.0002 21.1 0.0 0.071 12.7 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 EAK87388.1 - 0.00024 20.8 0.6 0.35 10.5 0.0 3.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EAK87388.1 - 0.00032 20.1 0.0 0.24 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EAK87388.1 - 0.00045 20.1 0.0 0.45 10.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 EAK87388.1 - 0.00075 18.7 0.0 5 6.2 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.14 EAK87388.1 - 0.0012 18.1 1.8 1.7 7.8 0.1 3.5 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain cobW PF02492.14 EAK87388.1 - 0.0014 18.0 1.3 0.041 13.3 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EAK87388.1 - 0.0015 17.6 0.0 0.011 14.8 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 EAK87388.1 - 0.0018 17.9 0.0 0.71 9.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain ATP_bind_1 PF03029.12 EAK87388.1 - 0.0018 17.8 0.2 2.3 7.6 0.0 2.7 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 EAK87388.1 - 0.0031 16.1 0.3 0.92 8.0 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain ArgK PF03308.11 EAK87388.1 - 0.0046 15.7 0.1 0.3 9.8 0.0 2.3 2 0 0 2 2 2 1 ArgK protein RNA_helicase PF00910.17 EAK87388.1 - 0.005 16.9 0.1 0.54 10.4 0.0 3.0 2 0 0 2 2 2 1 RNA helicase GvpD PF07088.6 EAK87388.1 - 0.0055 15.0 0.0 0.01 14.1 0.0 1.3 1 0 0 1 1 1 1 GvpD gas vesicle protein Viral_helicase1 PF01443.13 EAK87388.1 - 0.013 15.0 0.0 3.8 6.9 0.0 2.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EAK87388.1 - 0.016 14.9 0.7 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 EAK87388.1 - 0.024 14.4 0.1 0.58 9.9 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain PduV-EutP PF10662.4 EAK87388.1 - 0.025 14.0 0.1 3.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EAK87388.1 - 0.03 14.5 0.1 0.22 11.7 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAK87388.1 - 0.064 12.9 0.0 3.5 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EAK87388.1 - 0.16 12.2 0.1 0.16 12.2 0.1 4.5 4 1 1 5 5 3 0 AAA domain AAA_28 PF13521.1 EAK87388.1 - 0.48 10.3 1.4 0.87 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain RseC_MucC PF04246.7 EAK87388.1 - 8.5 5.9 7.2 24 4.5 1.5 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ABC_tran PF00005.22 EAK87389.1 - 2.9e-33 115.0 0.0 1.1e-15 58.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter MMR_HSR1 PF01926.18 EAK87389.1 - 2.9e-09 36.8 0.0 0.00077 19.4 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase ABC_membrane PF00664.18 EAK87389.1 - 1.4e-08 34.5 23.4 4.1e-07 29.7 7.2 3.4 4 0 0 4 4 3 2 ABC transporter transmembrane region AAA_16 PF13191.1 EAK87389.1 - 1.7e-08 34.6 0.0 9.2e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EAK87389.1 - 7.2e-07 29.7 0.1 0.049 14.1 0.0 3.6 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 EAK87389.1 - 1.6e-06 27.5 0.0 0.054 13.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.17 EAK87389.1 - 7e-06 26.1 0.0 0.0031 17.6 0.0 3.1 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 EAK87389.1 - 1.4e-05 25.2 0.4 0.018 15.1 0.0 3.1 4 0 0 4 4 2 1 AAA domain DUF258 PF03193.11 EAK87389.1 - 1.8e-05 24.0 0.0 0.016 14.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EAK87389.1 - 3.3e-05 23.7 2.3 0.00061 19.5 0.0 3.2 4 0 0 4 4 3 1 Archaeal ATPase T2SE PF00437.15 EAK87389.1 - 3.8e-05 22.7 0.0 0.067 12.0 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 EAK87389.1 - 5.9e-05 23.8 0.0 0.33 11.7 0.0 3.1 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EAK87389.1 - 6.8e-05 21.9 0.7 0.0072 15.2 0.0 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF815) SMC_N PF02463.14 EAK87389.1 - 0.00011 21.5 0.1 0.22 10.7 0.0 3.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 EAK87389.1 - 0.00014 21.0 0.0 0.0016 17.5 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin AAA_10 PF12846.2 EAK87389.1 - 0.00027 20.4 0.1 0.74 9.1 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_25 PF13481.1 EAK87389.1 - 0.0004 19.8 0.0 0.12 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EAK87389.1 - 0.00063 19.6 0.0 1.8 8.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EAK87389.1 - 0.00087 18.1 0.0 0.19 10.4 0.0 2.2 2 0 0 2 2 2 1 ArgK protein Viral_helicase1 PF01443.13 EAK87389.1 - 0.00092 18.7 0.0 0.037 13.5 0.0 2.8 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 EAK87389.1 - 0.0013 18.4 0.0 0.23 11.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 EAK87389.1 - 0.0014 18.8 0.0 0.0071 16.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAK87389.1 - 0.0021 17.7 0.0 0.15 11.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EAK87389.1 - 0.0032 16.3 0.0 0.38 9.5 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain FtsK_SpoIIIE PF01580.13 EAK87389.1 - 0.0034 16.9 0.1 0.044 13.2 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EAK87389.1 - 0.0034 17.6 3.1 1.3 9.2 0.0 3.4 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.10 EAK87389.1 - 0.0046 16.6 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 1 NTPase MobB PF03205.9 EAK87389.1 - 0.0057 16.3 0.0 2.9 7.5 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 EAK87389.1 - 0.015 14.5 0.0 1.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Dynamin_N PF00350.18 EAK87389.1 - 0.036 13.8 6.1 2.1 8.1 0.0 3.1 3 0 0 3 3 2 0 Dynamin family ATP_bind_1 PF03029.12 EAK87389.1 - 0.081 12.4 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.21 EAK87389.1 - 0.11 12.0 0.0 9.3 5.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EAK87389.1 - 0.19 11.1 0.0 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.1 EAK87389.1 - 0.75 9.3 0.0 45 3.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain PRK PF00485.13 EAK87389.1 - 4.8 6.6 6.7 6.3 6.3 0.1 3.3 3 1 1 4 4 4 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 EAK87390.1 - 1.3e-27 96.7 0.1 3.5e-14 53.2 0.0 2.9 2 1 0 2 2 2 2 ABC transporter Miro PF08477.8 EAK87390.1 - 2.9e-09 37.4 0.4 0.0019 18.6 0.0 4.0 5 0 0 5 5 4 2 Miro-like protein DUF258 PF03193.11 EAK87390.1 - 6.3e-08 31.9 0.5 0.0048 16.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EAK87390.1 - 1.2e-07 31.1 0.8 0.0048 16.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EAK87390.1 - 1.2e-06 28.4 0.3 0.0031 17.4 0.1 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EAK87390.1 - 1.4e-06 28.0 0.8 0.034 13.6 0.3 2.6 2 0 0 2 2 2 2 AAA-like domain AAA_17 PF13207.1 EAK87390.1 - 4.1e-06 27.6 0.2 0.35 11.6 0.0 3.6 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 EAK87390.1 - 1.2e-05 24.9 0.7 0.0054 16.2 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 EAK87390.1 - 2.3e-05 24.6 0.4 0.44 10.8 0.0 3.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EAK87390.1 - 3.6e-05 23.8 0.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EAK87390.1 - 4.1e-05 23.7 0.0 0.031 14.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EAK87390.1 - 5.6e-05 22.8 0.7 0.2 11.3 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EAK87390.1 - 0.00011 21.9 1.0 0.028 14.0 0.0 2.9 3 0 0 3 3 3 1 NACHT domain PduV-EutP PF10662.4 EAK87390.1 - 0.00031 20.2 0.5 0.2 11.1 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EAK87390.1 - 0.0012 18.9 6.4 0.67 10.1 0.0 4.4 4 0 0 4 4 4 2 RNA helicase T2SE PF00437.15 EAK87390.1 - 0.0013 17.6 0.4 0.76 8.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EAK87390.1 - 0.0018 17.6 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EAK87390.1 - 0.0019 17.7 0.0 1.3 8.4 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 EAK87390.1 - 0.0024 17.7 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EAK87390.1 - 0.0036 17.1 4.2 0.41 10.4 1.3 3.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 EAK87390.1 - 0.0091 15.5 0.0 0.81 9.1 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 EAK87390.1 - 0.01 14.6 1.0 1.3 7.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.18 EAK87390.1 - 0.011 15.5 1.0 0.011 15.5 0.7 4.0 4 1 0 4 4 4 0 Dynamin family cobW PF02492.14 EAK87390.1 - 0.014 14.8 2.5 2.8 7.3 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EAK87390.1 - 0.019 14.4 0.0 2.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SMC_N PF02463.14 EAK87390.1 - 0.022 13.9 13.8 1.1 8.4 1.1 4.0 3 1 1 4 4 4 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 EAK87390.1 - 0.038 13.6 2.0 0.39 10.3 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EAK87390.1 - 0.093 12.4 1.3 0.72 9.5 0.0 2.5 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.16 EAK87390.1 - 0.097 11.8 0.0 13 4.8 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EAK87390.1 - 0.12 12.0 0.6 2.3 8.0 0.0 2.7 3 0 0 3 3 3 0 Part of AAA domain ArgK PF03308.11 EAK87390.1 - 0.48 9.1 0.1 3.7 6.2 0.1 2.0 2 0 0 2 2 2 0 ArgK protein Nop PF01798.13 EAK87391.1 - 1.9e-55 186.2 0.5 3.9e-55 185.2 0.3 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EAK87391.1 - 1e-24 86.0 0.2 6.9e-24 83.4 0.0 2.4 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EAK87391.1 - 4e-16 58.9 0.0 4e-16 58.9 0.0 2.8 3 0 0 3 3 3 1 NOP5NT (NUC127) domain Exo_endo_phos PF03372.18 EAK87392.1 - 3.6e-13 50.0 0.0 5e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EAK87392.1 - 2.2e-11 43.4 0.0 1.6e-10 40.6 0.0 2.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EAK87392.1 - 2.7e-10 39.9 3.0 6.9e-10 38.6 2.1 1.7 1 0 0 1 1 1 1 GRF zinc finger Aminotran_5 PF00266.14 EAK87393.1 - 8.1e-37 126.8 0.0 2.2e-36 125.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Protamine_3 PF08188.6 EAK87394.1 - 0.12 12.3 3.0 0.7 9.9 0.1 3.0 2 0 0 2 2 2 0 Spermatozal protamine family Ribosomal_L39 PF00832.15 EAK87395.1 - 2.1e-20 71.8 7.9 2.4e-20 71.7 5.5 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Nucleoplasmin PF03066.10 EAK87396.1 - 8.4e-07 28.6 4.9 8.4e-07 28.6 3.4 3.6 1 1 1 2 2 2 1 Nucleoplasmin DUF605 PF04652.11 EAK87396.1 - 0.074 12.4 20.0 0.09 12.1 13.9 1.1 1 0 0 1 1 1 0 Vta1 like CENP-T PF15511.1 EAK87396.1 - 0.44 9.7 32.9 0.8 8.8 22.8 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ndc1_Nup PF09531.5 EAK87396.1 - 3.4 5.9 6.9 4.1 5.6 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF572 PF04502.8 EAK87396.1 - 4 6.5 29.8 5.7 6.0 20.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_S24e PF01282.14 EAK87397.1 - 2.6e-29 100.8 0.0 4.4e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e HSP70 PF00012.15 EAK87398.1 - 6.7e-272 902.7 6.0 7.7e-272 902.6 4.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EAK87398.1 - 2.3e-16 59.3 0.1 1.5e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 EAK87398.1 - 0.014 14.2 0.3 0.14 10.9 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EAK87398.1 - 0.026 13.6 4.4 0.05 12.6 0.1 2.6 2 1 0 3 3 3 0 Hydantoinase/oxoprolinase Thioredox_DsbH PF03190.10 EAK87398.1 - 0.095 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF255 PKK PF12474.3 EAK87398.1 - 8.8 6.0 16.0 2.6 7.7 8.6 1.8 2 0 0 2 2 2 0 Polo kinase kinase DEAD PF00270.24 EAK87399.1 - 1.6e-33 115.5 0.4 1.9e-32 112.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK87399.1 - 3.2e-23 81.3 0.8 6.3e-22 77.2 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAK87399.1 - 1.6e-10 41.1 0.0 1.6e-10 41.1 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EAK87399.1 - 0.026 13.7 2.8 0.56 9.4 1.7 2.9 1 1 0 1 1 1 0 SecA DEAD-like domain Helicase_C_2 PF13307.1 EAK87399.1 - 0.029 14.3 1.0 3.5 7.5 0.1 2.8 2 1 1 3 3 3 0 Helicase C-terminal domain AAA_19 PF13245.1 EAK87399.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Part of AAA domain AHSA1 PF08327.6 EAK87400.1 - 1.8e-15 57.1 0.0 2e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein RAMP4 PF06624.7 EAK87401.1 - 4.6e-26 90.1 0.2 5.1e-26 89.9 0.1 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3951 PF13131.1 EAK87401.1 - 0.046 13.5 1.1 0.064 13.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) DUF1777 PF08648.7 EAK87403.1 - 0.00012 21.8 37.3 0.00012 21.8 25.9 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1777) PRP38_assoc PF12871.2 EAK87403.1 - 0.0011 19.4 38.4 0.0011 19.4 26.6 4.0 2 1 2 4 4 4 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Aa_trans PF01490.13 EAK87405.1 - 2.7e-46 157.8 44.1 3.6e-46 157.4 30.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SWI-SNF_Ssr4 PF08549.5 EAK87406.1 - 0.61 8.3 5.2 0.62 8.2 3.6 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SnAC PF14619.1 EAK87406.1 - 0.68 10.1 5.9 2.1 8.5 4.1 2.1 1 1 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex DUF2654 PF10849.3 EAK87406.1 - 3.5 7.4 8.4 0.44 10.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) PHD PF00628.24 EAK87407.1 - 6.7e-13 48.1 4.2 6.7e-13 48.1 2.9 2.8 3 0 0 3 3 3 1 PHD-finger zf-rbx1 PF12678.2 EAK87407.1 - 1.4e-06 28.3 4.6 1.4e-06 28.3 3.2 3.4 2 1 1 3 3 3 2 RING-H2 zinc finger zf-RING_2 PF13639.1 EAK87407.1 - 9.6e-06 25.3 3.6 9.6e-06 25.3 2.5 3.7 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EAK87407.1 - 0.0001 21.8 4.9 0.0001 21.8 3.4 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK87407.1 - 0.00045 19.8 4.3 0.00045 19.8 3.0 3.2 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAK87407.1 - 0.00082 19.0 4.1 0.00082 19.0 2.8 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK87407.1 - 0.0018 18.2 5.3 0.0018 18.2 3.7 3.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EAK87407.1 - 0.041 13.7 10.7 0.03 14.1 0.7 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EAK87407.1 - 0.27 11.0 6.3 0.04 13.7 0.9 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C2H2_6 PF13912.1 EAK87407.1 - 2 8.4 5.8 2.2 8.3 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Myosin_tail_1 PF01576.14 EAK87409.1 - 0.00023 19.0 6.5 0.00034 18.4 4.5 1.3 1 0 0 1 1 1 1 Myosin tail DUF2968 PF11180.3 EAK87409.1 - 0.00034 20.0 3.3 0.00057 19.3 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) DUF641 PF04859.7 EAK87409.1 - 0.0014 18.3 1.3 0.0014 18.3 0.9 2.3 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.6 EAK87409.1 - 0.0026 17.2 6.7 0.0026 17.2 4.6 2.3 2 0 0 2 2 2 1 Phage minor structural protein GP20 ADIP PF11559.3 EAK87409.1 - 0.0077 16.1 7.0 0.017 14.9 4.8 1.6 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF3595 PF12166.3 EAK87409.1 - 0.016 14.0 0.3 0.02 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) NPV_P10 PF05531.7 EAK87409.1 - 0.021 15.0 0.4 0.061 13.5 0.3 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF947 PF06102.7 EAK87409.1 - 0.028 14.2 4.5 0.056 13.2 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF947) Tropomyosin_1 PF12718.2 EAK87409.1 - 0.07 12.9 13.0 0.14 12.0 9.0 1.5 1 0 0 1 1 1 0 Tropomyosin like Tup_N PF08581.5 EAK87409.1 - 0.077 13.1 5.9 0.32 11.2 0.3 3.0 1 1 0 2 2 2 0 Tup N-terminal USP8_interact PF08941.5 EAK87409.1 - 0.079 12.2 2.6 0.088 12.1 0.6 1.9 2 0 0 2 2 2 0 USP8 interacting IncA PF04156.9 EAK87409.1 - 0.093 12.3 11.7 0.19 11.3 8.1 1.6 1 0 0 1 1 1 0 IncA protein BRE1 PF08647.6 EAK87409.1 - 0.1 12.5 6.3 0.28 11.1 4.3 1.7 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase APG6 PF04111.7 EAK87409.1 - 0.12 11.4 10.1 0.22 10.5 7.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Takusan PF04822.8 EAK87409.1 - 0.31 10.8 8.8 0.18 11.5 2.5 2.7 2 1 0 2 2 2 0 Takusan V_ATPase_I PF01496.14 EAK87409.1 - 0.43 8.3 3.4 0.57 7.9 2.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EAK87409.1 - 0.55 10.3 9.7 0.071 13.2 0.9 3.0 2 1 0 3 3 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.1 EAK87409.1 - 1.8 8.5 7.5 0.22 11.4 1.9 2.1 2 0 0 2 2 1 0 FlxA-like protein Cortex-I_coil PF09304.5 EAK87409.1 - 3 7.9 18.1 0.84 9.7 2.0 3.1 3 1 1 4 4 4 0 Cortexillin I, coiled coil DUF342 PF03961.8 EAK87409.1 - 4.5 5.5 9.7 6.8 4.9 6.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) NAF PF03822.9 EAK87410.1 - 0.0099 15.5 0.8 0.028 14.1 0.6 1.7 1 0 0 1 1 1 1 NAF domain DUF2203 PF09969.4 EAK87410.1 - 0.029 14.5 0.4 0.065 13.4 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Ly49 PF08391.5 EAK87411.1 - 0.09 12.9 4.3 0.14 12.3 0.5 2.6 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region zf-RING_2 PF13639.1 EAK87412.1 - 1.6e-12 47.0 4.1 3.3e-12 46.0 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAK87412.1 - 2.2e-07 30.7 4.7 8e-07 28.9 3.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAK87412.1 - 5.5e-06 26.0 4.0 1.2e-05 24.9 0.9 3.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EAK87412.1 - 6.1e-06 25.7 5.7 4.1e-05 23.1 3.9 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK87412.1 - 1.6e-05 24.5 2.6 4.5e-05 23.1 1.8 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EAK87412.1 - 4.7e-05 23.4 7.2 0.00019 21.4 4.7 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EAK87412.1 - 0.00056 19.5 5.4 0.0013 18.3 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAK87412.1 - 0.003 17.4 1.7 0.003 17.4 1.2 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EAK87412.1 - 0.014 15.1 1.2 0.014 15.1 0.9 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EAK87412.1 - 0.077 13.0 4.1 0.22 11.5 2.9 1.9 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 EAK87412.1 - 0.25 11.0 5.0 0.11 12.2 1.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 bZIP_1 PF00170.16 EAK87412.1 - 1.3 8.9 19.1 4.5 7.3 3.1 4.2 2 2 1 3 3 3 0 bZIP transcription factor FANCL_C PF11793.3 EAK87412.1 - 1.7 8.6 8.4 10 6.1 5.9 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain AAA_22 PF13401.1 EAK87413.1 - 1.7e-12 47.6 0.0 3.6e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EAK87413.1 - 1.2e-11 44.9 0.0 2.7e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAK87413.1 - 3.2e-06 27.2 0.0 8.5e-05 22.6 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 EAK87413.1 - 0.00067 19.2 4.7 0.024 14.2 0.0 2.5 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EAK87413.1 - 0.0013 18.4 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EAK87413.1 - 0.0024 16.9 0.0 0.0055 15.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EAK87413.1 - 0.073 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EAK87413.1 - 0.13 11.7 0.3 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Bacillus_HBL PF05791.6 EAK87414.1 - 0.0054 16.1 7.6 0.0054 16.1 5.2 4.1 3 1 1 4 4 4 2 Bacillus haemolytic enterotoxin (HBL) DUF2051 PF09738.4 EAK87414.1 - 0.0066 15.7 9.7 0.0066 15.7 6.8 4.5 3 2 1 4 4 4 1 Double stranded RNA binding protein (DUF2051) SlyX PF04102.7 EAK87414.1 - 0.0084 16.4 8.9 0.0084 16.4 6.1 7.1 5 2 3 9 9 9 1 SlyX DUF1664 PF07889.7 EAK87414.1 - 0.15 11.8 37.0 0.55 10.0 3.9 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) FliJ PF02050.11 EAK87414.1 - 0.41 10.7 48.0 0.12 12.3 7.3 5.0 2 2 3 5 5 5 0 Flagellar FliJ protein Reo_sigmaC PF04582.7 EAK87414.1 - 0.43 9.7 11.5 0.61 9.2 0.1 3.2 3 0 0 3 3 3 0 Reovirus sigma C capsid protein KIP1 PF07765.7 EAK87414.1 - 1.1 9.0 13.0 0.91 9.4 0.1 4.5 3 3 2 5 5 5 0 KIP1-like protein ATG16 PF08614.6 EAK87414.1 - 2 8.1 54.4 2.4 7.9 11.6 3.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) PSI_PsaF PF02507.10 EAK87414.1 - 2.2 7.7 7.2 0.42 10.1 0.1 2.8 2 1 1 3 3 3 0 Photosystem I reaction centre subunit III BLOC1_2 PF10046.4 EAK87414.1 - 2.7 8.1 36.8 0.055 13.6 0.6 5.1 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 EAK87414.1 - 2.9 6.8 54.0 0.039 12.9 4.4 3.5 3 1 0 3 3 3 0 Autophagy protein Apg6 IncA PF04156.9 EAK87414.1 - 3.4 7.2 78.3 0.24 10.9 9.0 5.2 3 2 1 5 5 5 0 IncA protein DAGK_acc PF00609.14 EAK87416.1 - 6.3e-31 107.6 0.3 4.8e-16 59.3 0.0 2.2 1 1 1 2 2 2 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EAK87416.1 - 2.9e-19 68.7 0.0 4.9e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Citrus_P18 PF05520.6 EAK87416.1 - 0.053 13.0 1.5 0.17 11.3 0.3 2.1 2 0 0 2 2 2 0 Citrus tristeza virus P18 protein zf-RING_2 PF13639.1 EAK87417.1 - 2.6e-12 46.3 12.1 5e-12 45.4 8.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EAK87417.1 - 2.2e-09 36.8 7.5 3.6e-09 36.1 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK87417.1 - 6.2e-09 35.7 12.9 1.1e-08 34.9 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAK87417.1 - 3.2e-08 33.1 11.6 6.2e-08 32.1 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EAK87417.1 - 6.3e-08 32.6 6.3 1.5e-07 31.4 4.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EAK87417.1 - 1.9e-07 30.6 9.5 3.4e-07 29.8 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EAK87417.1 - 6.7e-05 22.5 6.0 0.00021 20.9 1.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EAK87417.1 - 0.02 14.7 4.9 0.041 13.7 3.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EAK87417.1 - 0.045 13.5 4.0 0.098 12.4 2.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EAK87417.1 - 0.15 11.9 11.9 1.1 9.2 8.5 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF1244 PF06844.6 EAK87417.1 - 0.22 11.3 1.9 0.71 9.7 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) Spc97_Spc98 PF04130.8 EAK87418.1 - 1.4e-10 40.1 21.0 1.4e-10 40.1 14.6 2.9 2 1 0 2 2 2 1 Spc97 / Spc98 family Spc97_Spc98 PF04130.8 EAK87419.1 - 2.9e-19 68.7 8.8 2.8e-18 65.5 6.1 2.0 1 1 0 1 1 1 1 Spc97 / Spc98 family TPP1 PF10341.4 EAK87419.1 - 0.031 14.2 0.1 7.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Shelterin complex subunit, TPP1/ACD Peptidase_M16_C PF05193.16 EAK87423.1 - 4.5e-06 26.4 0.8 0.0005 19.7 0.0 3.4 3 2 0 3 3 3 2 Peptidase M16 inactive domain TPR_11 PF13414.1 EAK87426.1 - 3.8e-09 36.0 0.6 0.0007 19.1 0.5 2.8 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 EAK87426.1 - 6.4e-08 31.8 2.1 0.021 14.5 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAK87426.1 - 1.8e-07 30.5 2.4 0.013 15.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAK87426.1 - 1.7e-05 25.0 0.1 0.0034 17.8 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAK87426.1 - 2e-05 25.1 0.0 0.19 12.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAK87426.1 - 3e-05 23.4 0.2 0.034 13.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAK87426.1 - 3.8e-05 23.9 0.0 0.18 12.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAK87426.1 - 4.8e-05 23.1 1.0 0.4 10.6 0.1 3.5 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 EAK87426.1 - 5.1e-05 23.1 0.1 0.09 12.7 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAK87426.1 - 0.00041 19.8 0.2 0.031 13.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EAK87426.1 - 0.0055 16.5 0.2 0.64 9.9 0.0 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EAK87426.1 - 0.007 16.4 2.4 0.096 12.8 1.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 RNA_pol_I_TF PF04090.7 EAK87426.1 - 0.028 13.7 2.5 0.055 12.7 1.8 1.5 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor TPR_6 PF13174.1 EAK87426.1 - 0.1 13.0 0.0 3.5 8.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Vfa1 PF08432.5 EAK87427.1 - 0.28 11.2 5.2 0.33 10.9 3.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sel1 PF08238.7 EAK87430.1 - 1.4e-10 41.4 13.2 0.0082 16.7 0.2 4.7 5 0 0 5 5 5 3 Sel1 repeat Peptidase_C14 PF00656.17 EAK87431.1 - 1.9e-37 129.3 0.0 8e-37 127.2 0.0 2.1 1 1 0 1 1 1 1 Caspase domain DUF155 PF02582.9 EAK87432.1 - 1.2e-50 171.8 0.1 1.8e-50 171.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 CRAL_TRIO PF00650.15 EAK87433.1 - 4.6e-24 84.7 0.0 1.4e-23 83.1 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.1 EAK87433.1 - 0.00059 20.0 0.1 0.00059 20.0 0.1 4.6 2 2 2 5 5 5 1 Golgi-dynamics membrane-trafficking MFS_1 PF07690.11 EAK87435.1 - 6.2e-33 113.9 55.3 1.6e-26 92.8 20.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EAK87435.1 - 0.0091 15.7 0.2 0.0091 15.7 0.1 3.0 4 0 0 4 4 4 1 MFS_1 like family PC_rep PF01851.17 EAK87436.1 - 2.2e-34 115.7 13.4 0.00084 19.4 0.0 10.4 10 0 0 10 10 10 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EAK87436.1 - 9.1e-20 70.7 0.0 2.4e-10 40.5 0.0 5.8 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.17 EAK87436.1 - 6.7e-07 28.8 0.1 0.0044 16.9 0.0 4.6 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 EAK87436.1 - 2.1e-06 28.0 0.0 0.063 13.7 0.0 5.3 3 1 3 6 6 6 3 HEAT-like repeat DUF1546 PF07571.8 EAK87436.1 - 0.061 13.4 0.0 0.55 10.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) TPR_2 PF07719.12 EAK87436.1 - 0.074 12.9 1.1 1.2 9.2 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAK87436.1 - 0.098 12.6 0.5 0.68 9.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EAK87436.1 - 0.12 12.4 2.7 2.1 8.5 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EAK87436.1 - 0.13 11.8 1.5 1.5 8.5 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF836 PF05768.9 EAK87437.1 - 0.044 14.0 5.6 0.061 13.5 3.3 1.8 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) CCDC92 PF14916.1 EAK87437.1 - 0.089 12.3 0.6 0.089 12.3 0.4 2.4 3 0 0 3 3 3 0 Coiled-coil domain of unknown function V_ATPase_I PF01496.14 EAK87437.1 - 0.13 10.0 11.7 0.16 9.7 8.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YlqD PF11068.3 EAK87437.1 - 0.52 10.3 10.1 0.58 10.2 4.2 2.0 1 1 1 2 2 2 0 YlqD protein Syntaxin-6_N PF09177.6 EAK87437.1 - 0.75 10.2 8.3 0.69 10.3 2.5 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF730 PF05325.6 EAK87437.1 - 0.85 9.4 4.8 1.6 8.5 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF730) bZIP_1 PF00170.16 EAK87437.1 - 0.85 9.6 17.7 1.4 8.9 1.0 3.3 3 0 0 3 3 3 0 bZIP transcription factor Ax_dynein_light PF10211.4 EAK87437.1 - 0.97 9.2 16.2 1.7 8.4 5.9 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Turandot PF07240.6 EAK87437.1 - 1.1 8.7 6.2 9.4 5.8 0.2 2.3 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot IncA PF04156.9 EAK87437.1 - 2 8.0 15.7 4.4 6.8 8.3 2.5 1 1 1 2 2 2 0 IncA protein DUF745 PF05335.8 EAK87437.1 - 3.5 7.1 6.5 5.2 6.5 4.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF745) CENP-H PF05837.7 EAK87437.1 - 7.8 6.7 14.0 2.7 8.2 5.0 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) bZIP_2 PF07716.10 EAK87437.1 - 7.9 6.3 13.7 1.8 8.4 0.4 3.2 3 0 0 3 3 3 0 Basic region leucine zipper Acetyltransf_1 PF00583.19 EAK87438.1 - 2.4e-14 53.1 0.0 3.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EAK87438.1 - 4.4e-09 36.4 0.0 5.4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EAK87438.1 - 5.4e-09 36.0 0.1 7.9e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAK87438.1 - 1.8e-08 34.4 0.1 2.2e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAK87438.1 - 4.1e-05 23.2 0.0 6.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EAK87438.1 - 5.1e-05 23.4 0.0 6.2e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EAK87438.1 - 0.00011 22.0 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EAK87438.1 - 0.00011 22.0 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EAK87438.1 - 0.0014 18.5 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Clenterotox PF03505.9 EAK87438.1 - 0.026 13.9 0.0 0.057 12.8 0.0 1.6 2 0 0 2 2 2 0 Clostridium enterotoxin Ribonuc_red_2_N PF08471.5 EAK87439.1 - 0.017 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase Cas_APE2256 PF09651.5 EAK87439.1 - 0.039 13.6 0.0 0.098 12.3 0.0 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) Vps51 PF08700.6 EAK87440.1 - 8.3e-11 41.5 2.7 8.3e-11 41.5 1.9 3.5 3 0 0 3 3 3 1 Vps51/Vps67 TFIIF_alpha PF05793.7 EAK87441.1 - 1.2 7.4 40.5 0.2 9.9 11.8 2.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 EAK87441.1 - 9.1 4.1 20.0 1.3 7.0 3.5 2.2 2 0 0 2 2 2 0 CDC45-like protein PPI_Ypi1 PF07491.6 EAK87442.1 - 4.2e-15 55.1 28.5 9e-14 50.8 19.8 2.7 1 1 0 1 1 1 1 Protein phosphatase inhibitor Aconitase_C PF00694.14 EAK87442.1 - 0.091 12.8 2.8 0.12 12.4 1.9 1.2 1 0 0 1 1 1 0 Aconitase C-terminal domain FAM176 PF14851.1 EAK87442.1 - 0.99 9.0 7.4 5 6.7 0.0 2.2 2 0 0 2 2 2 0 FAM176 family TFIIF_alpha PF05793.7 EAK87442.1 - 9.3 4.4 22.9 11 4.3 15.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNase_PH PF01138.16 EAK87443.1 - 8.8e-24 84.3 0.3 1.3e-23 83.7 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 TBPIP PF07106.8 EAK87443.1 - 0.01 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RNase_PH_C PF03725.10 EAK87443.1 - 0.017 15.0 0.1 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 IMS PF00817.15 EAK87444.1 - 7.4e-31 106.9 0.0 9.7e-31 106.5 0.0 1.1 1 0 0 1 1 1 1 impB/mucB/samB family CDC45 PF02724.9 EAK87445.1 - 2.1 6.2 15.3 3.6 5.5 10.6 1.4 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 EAK87445.1 - 3 6.0 26.5 5.3 5.2 18.4 1.3 1 0 0 1 1 1 0 Transmembrane protein Na_trans_assoc PF06512.8 EAK87445.1 - 6.3 6.7 17.7 15 5.4 12.3 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated Thymidylat_synt PF00303.14 EAK87446.1 - 5.1e-113 376.5 0.0 6.6e-113 376.1 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.14 EAK87446.1 - 5.5e-36 123.5 0.0 1.5e-35 122.1 0.0 1.7 2 0 0 2 2 2 1 Dihydrofolate reductase HD_2 PF12917.2 EAK87446.1 - 0.012 15.4 0.2 0.047 13.4 0.1 1.9 1 1 1 2 2 2 0 HD containing hydrolase-like enzyme OTU PF02338.14 EAK87447.1 - 3.3e-14 53.4 0.3 4e-14 53.2 0.2 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EAK87447.1 - 1.5e-07 31.0 2.1 1.8e-07 30.7 1.5 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain Succ_DH_flav_C PF02910.15 EAK87447.1 - 0.01 15.6 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term Phage_int_SAM_3 PF14659.1 EAK87447.1 - 0.11 12.8 1.7 0.24 11.7 0.5 2.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Adaptin_N PF01602.15 EAK87448.1 - 1.9e-124 415.8 17.6 2.7e-124 415.3 12.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EAK87448.1 - 6.1e-21 75.0 0.4 6.1e-21 75.0 0.3 4.1 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EAK87448.1 - 1.6e-16 60.3 0.0 6e-10 39.2 0.0 4.8 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EAK87448.1 - 6.8e-10 38.1 4.8 0.0011 18.9 0.0 6.1 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EAK87448.1 - 0.0012 19.2 1.8 0.2 12.1 0.0 4.8 5 1 1 6 6 6 1 HEAT-like repeat Atx10homo_assoc PF09759.4 EAK87448.1 - 0.032 13.9 1.1 1.9 8.2 0.0 4.1 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain RHH_3 PF12651.2 EAK87448.1 - 0.051 13.3 0.7 0.32 10.7 0.1 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix domain HTH_36 PF13730.1 EAK87448.1 - 0.29 11.2 3.3 2.9 8.0 0.1 3.5 3 0 0 3 3 3 0 Helix-turn-helix domain Peptidase_M14 PF00246.19 EAK87449.1 - 2.7e-19 69.8 0.1 5.7e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 EAK87449.1 - 3.2e-08 32.8 0.0 6.4e-08 31.8 0.0 1.5 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.3 EAK87449.1 - 7.4e-05 21.9 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) zf-B_box PF00643.19 EAK87450.1 - 1.4e-08 34.4 23.9 2.3e-05 24.1 3.7 3.0 3 0 0 3 3 3 2 B-box zinc finger GDI PF00996.13 EAK87451.1 - 2.3e-191 635.8 0.1 2.7e-191 635.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor DAO PF01266.19 EAK87451.1 - 0.0018 17.2 0.0 0.082 11.7 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Avidin PF01382.12 EAK87451.1 - 0.03 14.5 0.1 0.4 10.9 0.0 2.6 3 0 0 3 3 3 0 Avidin family FAD_binding_3 PF01494.14 EAK87451.1 - 0.21 10.5 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GN3L_Grn1 PF08701.6 EAK87452.1 - 1.4e-20 72.9 17.9 3.3e-20 71.7 12.4 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EAK87452.1 - 7.2e-17 61.4 1.0 2e-14 53.5 0.1 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EAK87452.1 - 3.9e-09 35.9 0.6 3.9e-06 26.2 0.1 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EAK87452.1 - 6.3e-06 25.4 0.6 1.3e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EAK87452.1 - 0.0047 16.3 0.6 1 8.7 0.0 3.2 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain T4SS PF07996.6 EAK87452.1 - 0.0073 16.1 0.3 0.015 15.1 0.2 1.5 1 0 0 1 1 1 1 Type IV secretion system proteins Miro PF08477.8 EAK87452.1 - 0.2 12.1 2.8 2.2 8.7 0.1 3.3 2 1 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 EAK87452.1 - 0.25 11.1 7.7 0.16 11.7 0.1 3.4 2 2 0 2 2 2 0 Dynamin family ArgK PF03308.11 EAK87452.1 - 0.29 9.8 0.0 0.29 9.8 0.0 1.8 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 EAK87452.1 - 0.69 10.2 0.0 0.69 10.2 0.0 2.6 3 1 0 3 3 3 0 ABC transporter Ribosomal_S5 PF00333.15 EAK87453.1 - 6.2e-28 96.3 0.9 1.1e-27 95.4 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EAK87453.1 - 9.9e-21 72.8 0.0 1.9e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PRP38_assoc PF12871.2 EAK87456.1 - 0.0016 18.9 62.0 0.016 15.7 11.7 3.7 3 0 0 3 3 3 2 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Transformer PF06495.6 EAK87456.1 - 0.004 17.0 22.6 0.004 17.0 15.7 3.3 2 1 0 3 3 3 1 Fruit fly transformer protein Serglycin PF04360.7 EAK87456.1 - 0.16 11.7 4.9 0.06 13.0 1.1 1.9 2 0 0 2 2 2 0 Serglycin Mrr_N PF14338.1 EAK87458.1 - 0.081 13.0 0.2 0.27 11.3 0.1 1.8 1 0 0 1 1 1 0 Mrr N-terminal domain Metallophos PF00149.23 EAK87460.1 - 1.2e-12 47.6 2.2 6.3e-12 45.3 1.5 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAK87460.1 - 0.0004 20.2 0.0 0.0016 18.2 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aa_trans PF01490.13 EAK87461.1 - 1e-58 198.7 39.0 1.2e-58 198.5 27.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EAK87461.1 - 0.00028 19.8 30.3 0.0014 17.5 21.0 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family TFIIIC_sub6 PF10419.4 EAK87464.1 - 0.061 12.7 0.1 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 TFIIIC subunit DUF340 PF03956.8 EAK87465.1 - 0.086 12.1 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Membrane protein of unknown function (DUF340) DUF543 PF04418.7 EAK87465.1 - 0.62 10.0 3.3 0.98 9.4 2.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF543) YL1 PF05764.8 EAK87466.1 - 2.2e-32 112.5 30.7 2.2e-32 112.5 21.3 2.3 1 1 1 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 EAK87466.1 - 1.6e-13 49.9 1.3 1.8e-12 46.5 0.2 2.5 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain DUF2051 PF09738.4 EAK87467.1 - 0.11 11.7 0.7 0.24 10.6 0.5 1.5 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) ThiF PF00899.16 EAK87468.1 - 0.024 14.4 0.1 0.072 12.9 0.0 1.8 1 1 0 1 1 1 0 ThiF family RNA_pol_Rpb2_6 PF00562.23 EAK87469.1 - 5.4e-120 400.6 0.0 8.8e-120 399.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EAK87469.1 - 6.7e-46 155.7 0.2 1.3e-45 154.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EAK87469.1 - 2.8e-28 97.9 0.0 7e-28 96.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EAK87469.1 - 8e-22 76.8 0.0 1.8e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.9 EAK87469.1 - 1.9e-20 73.1 0.2 6.2e-20 71.4 0.2 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EAK87469.1 - 4.6e-19 67.9 0.0 9.2e-19 66.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EAK87469.1 - 3.6e-12 46.0 0.0 1.9e-11 43.7 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 PAN_4 PF14295.1 EAK87470.1 - 5.3e-07 29.2 0.2 5.3e-07 29.2 0.2 3.6 3 2 0 3 3 3 2 PAN domain PAN_1 PF00024.21 EAK87470.1 - 5.5e-05 22.8 6.1 0.0021 17.8 1.3 3.0 2 0 0 2 2 2 2 PAN domain TSP_1 PF00090.14 EAK87470.1 - 0.005 16.9 2.6 0.005 16.9 1.8 4.5 3 1 1 4 4 4 3 Thrombospondin type 1 domain DEAD PF00270.24 EAK87472.1 - 5.4e-36 123.6 0.0 9.7e-35 119.5 0.0 2.8 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK87472.1 - 2.7e-23 81.6 0.1 5.8e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EAK87472.1 - 0.014 15.5 3.7 0.032 14.3 0.1 3.0 2 1 1 3 3 3 0 AAA domain DUF4345 PF14248.1 EAK87472.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) DUF2318 PF10080.4 EAK87474.1 - 0.00093 18.9 0.2 0.002 17.8 0.1 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) EXOSC1 PF10447.4 EAK87474.1 - 0.0022 17.9 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 MadL PF03817.8 EAK87475.1 - 0.022 14.5 0.5 0.076 12.8 0.0 2.0 2 0 0 2 2 2 0 Malonate transporter MadL subunit MOZ_SAS PF01853.13 EAK87476.1 - 2.7e-69 232.2 1.6 2.4e-66 222.5 1.1 2.3 2 0 0 2 2 2 2 MOZ/SAS family Tudor-knot PF11717.3 EAK87476.1 - 8.1e-10 38.2 0.9 1.8e-09 37.1 0.6 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.1 EAK87476.1 - 0.034 14.3 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAK87476.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2_4 PF13894.1 EAK87476.1 - 4.1 7.9 6.4 14 6.2 4.4 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Fumble PF03630.9 EAK87477.1 - 1.2e-26 93.4 4.8 1.9e-26 92.7 3.3 1.4 1 1 0 1 1 1 1 Fumble YtfJ_HI0045 PF09695.5 EAK87477.1 - 0.052 12.8 0.2 0.095 12.0 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) HIPIP PF01355.12 EAK87478.1 - 0.36 10.9 1.5 0.59 10.2 0.3 1.8 2 0 0 2 2 2 0 High potential iron-sulfur protein Metallophos PF00149.23 EAK87480.1 - 4.8e-09 35.8 0.1 9.3e-09 34.9 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAK87480.1 - 0.035 13.9 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RNA_pol_A_bac PF01000.21 EAK87481.1 - 4e-26 91.3 0.1 7.9e-26 90.4 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EAK87481.1 - 5.4e-20 70.2 0.0 7.1e-20 69.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.1 EAK87481.1 - 0.008 16.4 2.4 0.026 14.7 1.7 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EAK87481.1 - 0.01 16.1 1.6 0.028 14.8 1.1 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 EAK87481.1 - 0.014 15.2 1.4 0.033 13.9 1.0 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Arginase PF00491.16 EAK87481.1 - 0.07 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Arginase family Frigida PF07899.6 EAK87481.1 - 0.13 10.9 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Frigida-like protein tRNA-synt_2 PF00152.15 EAK87485.1 - 1.9e-74 250.4 0.1 1e-72 244.7 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EAK87485.1 - 0.00088 18.5 0.0 0.0093 15.1 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) DAO PF01266.19 EAK87486.1 - 4.5e-06 25.7 0.0 6.3e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Saccharop_dh PF03435.13 EAK87486.1 - 0.00044 19.3 0.0 0.00068 18.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EAK87486.1 - 0.0012 18.9 0.6 0.057 13.5 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EAK87486.1 - 0.0049 17.1 0.0 0.03 14.6 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain BLOC1_2 PF10046.4 EAK87486.1 - 0.05 13.7 2.3 0.66 10.1 0.0 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IPP-2 PF04979.9 EAK87487.1 - 5.2e-24 84.9 8.4 5.2e-24 84.9 5.9 1.6 1 1 1 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Ribosomal_L6 PF00347.18 EAK87488.1 - 1.2e-28 99.3 2.3 3.6e-14 53.0 0.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Beta-Casp PF10996.3 EAK87490.1 - 1.8e-32 111.9 0.0 2e-31 108.5 0.0 2.5 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EAK87490.1 - 8e-14 51.7 0.1 1.5e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EAK87490.1 - 1.2e-11 44.2 0.0 2.4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EAK87490.1 - 3e-10 39.9 0.2 1.6e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain CPSF73-100_C PF11718.3 EAK87490.1 - 9.6e-07 28.3 2.2 1.9e-06 27.4 1.5 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_3 PF13483.1 EAK87490.1 - 0.0013 18.4 0.0 0.0036 17.0 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain MRG PF05712.8 EAK87491.1 - 4.1e-19 68.2 3.9 5.8e-19 67.7 1.4 2.0 2 0 0 2 2 2 1 MRG Hist_deacetyl PF00850.14 EAK87492.1 - 1.2e-66 225.0 0.0 2.2e-66 224.2 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Ank_2 PF12796.2 EAK87492.1 - 4.3e-16 59.0 0.0 3.2e-10 40.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAK87492.1 - 3.7e-15 54.8 1.2 4.6e-07 29.3 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EAK87492.1 - 4.4e-15 55.7 0.6 7.4e-05 23.1 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAK87492.1 - 9.9e-15 53.1 0.8 8.7e-05 22.4 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EAK87492.1 - 6.7e-11 42.0 0.2 1.3e-05 25.2 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) AhpC-TSA PF00578.16 EAK87492.1 - 0.072 12.7 0.2 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 AhpC/TSA family DUF3267 PF11667.3 EAK87492.1 - 0.23 11.6 0.1 0.49 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3267) Myosin_tail_1 PF01576.14 EAK87493.1 - 0.00038 18.3 46.3 0.013 13.2 18.2 2.2 1 1 1 2 2 2 2 Myosin tail Reo_sigmaC PF04582.7 EAK87493.1 - 0.0028 16.8 5.1 0.0028 16.8 3.6 3.3 2 1 2 4 4 4 3 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 EAK87493.1 - 0.16 9.7 28.6 0.27 9.0 19.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EAK87493.1 - 0.31 10.6 47.6 0.016 14.8 13.4 3.6 1 1 2 3 3 3 0 IncA protein CENP-F_leu_zip PF10473.4 EAK87493.1 - 0.67 9.8 44.5 0.75 9.6 5.8 3.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 EAK87493.1 - 1 9.2 10.9 0.34 10.8 1.5 3.5 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 EAK87493.1 - 1.4 8.8 50.7 0.27 11.0 3.1 6.3 2 1 4 6 6 6 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EAK87493.1 - 1.9 8.4 44.7 2.3 8.0 6.9 4.7 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF812 PF05667.6 EAK87493.1 - 2 6.8 42.6 0.0051 15.3 16.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF812) Pox_A_type_inc PF04508.7 EAK87493.1 - 3.6 7.6 19.7 4.7 7.2 0.7 6.3 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Tropomyosin PF00261.15 EAK87493.1 - 6.4 5.7 40.6 2.1 7.3 5.6 3.6 1 1 1 3 3 3 0 Tropomyosin PseudoU_synth_1 PF01416.15 EAK87494.1 - 1.5e-26 92.8 0.0 3.6e-12 46.6 0.0 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase VIT1 PF01988.14 EAK87495.1 - 0.025 14.0 0.1 0.025 14.0 0.1 2.6 2 1 0 2 2 2 0 VIT family CENP-Q PF13094.1 EAK87495.1 - 0.26 11.3 35.2 14 5.6 0.0 3.2 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 EAK87495.1 - 0.34 10.7 0.1 0.34 10.7 0.0 3.5 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Ycf1 PF05758.7 EAK87495.1 - 0.39 8.3 31.8 0.27 8.9 1.2 2.0 2 0 0 2 2 2 0 Ycf1 Sigma70_ner PF04546.8 EAK87495.1 - 2.8 7.4 34.0 0.019 14.5 3.2 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region OAD_gamma PF04277.8 EAK87496.1 - 0.14 12.5 0.0 0.14 12.5 0.0 2.3 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain TSP_1 PF00090.14 EAK87497.1 - 0.057 13.5 0.1 0.057 13.5 0.1 4.7 4 1 2 6 6 6 0 Thrombospondin type 1 domain Abhydrolase_6 PF12697.2 EAK87499.1 - 1e-27 97.5 0.0 1.5e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAK87499.1 - 9.7e-17 61.0 0.0 6e-16 58.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAK87499.1 - 2.9e-13 49.9 0.0 1.2e-08 34.7 0.0 3.2 2 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 EAK87499.1 - 2.6e-06 26.8 0.0 0.0013 18.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EAK87499.1 - 2.4e-05 24.0 0.1 5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 EAK87499.1 - 0.0031 16.9 0.0 0.097 12.0 0.0 2.2 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) UPF0227 PF05728.7 EAK87499.1 - 0.0072 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) FAM91_C PF14648.1 EAK87499.1 - 0.029 13.2 0.7 0.033 13.0 0.1 1.4 2 0 0 2 2 2 0 FAM91 C-terminus AXE1 PF05448.7 EAK87499.1 - 0.041 12.3 0.1 0.2 10.1 0.1 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Med30 PF11315.3 EAK87499.1 - 0.046 13.8 0.1 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 30 Borrelia_orfD PF02999.9 EAK87499.1 - 0.053 13.6 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Borrelia orf-D family ITAM PF02189.10 EAK87500.1 - 0.0034 17.5 0.1 0.0034 17.5 0.1 2.3 3 0 0 3 3 3 1 Immunoreceptor tyrosine-based activation motif Proteasom_PSMB PF10508.4 EAK87501.1 - 1.2e-157 525.2 16.7 1.4e-157 524.9 11.5 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit DUF3639 PF12341.3 EAK87502.1 - 0.041 13.8 0.3 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) QueC PF06508.8 EAK87505.1 - 0.046 12.9 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC PhosphMutase PF10143.4 EAK87505.1 - 0.052 13.1 2.4 0.074 12.6 0.2 1.9 1 1 1 2 2 2 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase DivIC PF04977.10 EAK87505.1 - 0.11 12.0 10.7 0.33 10.4 0.2 3.2 3 0 0 3 3 3 0 Septum formation initiator DUF342 PF03961.8 EAK87505.1 - 2.4 6.4 6.9 1.2 7.5 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF4200 PF13863.1 EAK87505.1 - 6 6.8 16.6 20 5.1 4.7 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) TBP PF00352.16 EAK87506.1 - 1.2e-17 63.0 0.6 4.7e-07 29.0 0.0 3.2 3 0 0 3 3 3 3 Transcription factor TFIID (or TATA-binding protein, TBP) vATP-synt_E PF01991.13 EAK87507.1 - 1.6e-55 187.4 8.3 2.1e-55 187.1 5.8 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit FNIP_M PF14637.1 EAK87507.1 - 0.016 14.8 1.3 0.021 14.3 0.9 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain DUF4246 PF14033.1 EAK87507.1 - 0.16 10.5 3.1 0.16 10.5 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4246) FlhD PF05247.8 EAK87507.1 - 0.19 11.7 6.7 0.2 11.6 1.3 2.4 1 1 1 2 2 2 0 Flagellar transcriptional activator (FlhD) Mrr_N PF14338.1 EAK87507.1 - 0.34 11.0 3.6 0.57 10.2 2.5 1.3 1 0 0 1 1 1 0 Mrr N-terminal domain PcfK PF14058.1 EAK87507.1 - 0.34 11.0 9.1 0.036 14.1 3.2 1.6 2 0 0 2 2 2 0 PcfK-like protein Phage_min_cap2 PF06152.6 EAK87507.1 - 0.5 9.2 9.2 0.69 8.8 6.4 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 Salt_tol_Pase PF09506.5 EAK87507.1 - 1.2 7.6 6.2 0.21 10.1 0.6 1.9 1 1 1 2 2 2 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Ribosomal_L7Ae PF01248.21 EAK87509.1 - 1.3e-20 72.7 0.7 2.5e-20 71.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SMAP PF15477.1 EAK87509.1 - 1.8 8.9 9.7 0.67 10.2 0.8 3.2 4 0 0 4 4 4 0 Small acidic protein family Ribosomal_L18p PF00861.17 EAK87510.1 - 1.1e-38 132.0 0.0 1.1e-38 132.0 0.0 2.0 2 1 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EAK87510.1 - 6.9e-33 113.0 7.7 6.9e-33 113.0 5.3 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ycf1 PF05758.7 EAK87510.1 - 0.011 13.5 0.1 0.011 13.5 0.1 1.1 1 0 0 1 1 1 0 Ycf1 CAP_assoc_N PF14504.1 EAK87510.1 - 0.67 9.6 5.2 0.19 11.4 1.2 1.8 2 0 0 2 2 2 0 CAP-associated N-terminal DnaJ PF00226.26 EAK87511.1 - 5.8e-17 61.1 0.8 5.8e-17 61.1 0.6 2.7 3 0 0 3 3 3 1 DnaJ domain DUF2208 PF09973.4 EAK87511.1 - 0.17 11.1 3.8 0.33 10.1 2.7 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) SBDS_C PF09377.5 EAK87511.1 - 0.38 10.4 4.1 0.72 9.5 2.8 1.8 1 1 0 1 1 1 0 SBDS protein C-terminal domain FAA_hydrolase_N PF09298.6 EAK87511.1 - 4.6 7.2 5.7 2.3 8.2 0.6 2.6 1 1 2 3 3 3 0 Fumarylacetoacetase N-terminal EF-hand_8 PF13833.1 EAK87512.1 - 1.9e-12 46.5 2.2 2.3e-08 33.5 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EAK87512.1 - 3.8e-09 35.1 1.0 0.012 14.8 0.0 4.2 4 1 1 5 5 5 2 EF hand EF-hand_7 PF13499.1 EAK87512.1 - 8.5e-09 35.4 1.1 9.8e-08 32.0 0.5 2.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EAK87512.1 - 2.7e-08 32.9 1.6 0.03 14.1 0.1 4.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EAK87512.1 - 2.8e-05 23.2 4.9 0.076 12.3 0.0 4.1 4 1 1 5 5 5 2 EF hand EF-hand_9 PF14658.1 EAK87512.1 - 0.0083 16.0 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain PC_rep PF01851.17 EAK87513.1 - 4.2e-18 64.4 10.7 3.2e-05 23.9 0.1 8.1 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EAK87513.1 - 5.3e-06 26.6 0.0 0.0089 16.2 0.1 4.3 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 EAK87513.1 - 0.056 13.5 0.0 0.4 10.8 0.0 2.6 1 0 0 1 1 1 0 HEAT repeat Abhydrolase_6 PF12697.2 EAK87514.1 - 6.4e-19 68.7 0.0 9.4e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAK87514.1 - 5e-15 55.6 0.0 2.5e-14 53.4 0.0 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAK87514.1 - 2.1e-12 47.0 0.0 3.5e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAK87514.1 - 1.7e-05 24.5 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 EAK87514.1 - 0.00011 21.7 0.0 0.00084 18.8 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.16 EAK87514.1 - 0.0084 15.3 0.0 0.029 13.6 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1100 PF06500.6 EAK87514.1 - 0.089 11.3 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) RFC1 PF08519.7 EAK87515.1 - 3.1e-42 143.9 0.2 7.1e-42 142.7 0.1 1.7 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EAK87515.1 - 1.1e-13 51.1 0.0 3.6e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_pol3_delta PF06144.8 EAK87515.1 - 1.8e-09 37.3 0.1 1.8e-09 37.3 0.1 2.2 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 EAK87515.1 - 2e-08 34.5 0.0 7.6e-08 32.6 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PTCB-BRCT PF12738.2 EAK87515.1 - 8e-06 25.6 0.5 7.6e-05 22.4 0.0 2.5 2 0 0 2 2 2 1 twin BRCT domain AAA_17 PF13207.1 EAK87515.1 - 0.00016 22.5 3.9 0.00016 22.4 0.0 3.0 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.1 EAK87515.1 - 0.00024 21.2 0.0 0.00084 19.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAK87515.1 - 0.003 17.8 0.0 0.003 17.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EAK87515.1 - 0.0067 16.4 0.1 0.015 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EAK87515.1 - 0.0077 15.3 0.0 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EAK87515.1 - 0.013 15.2 0.0 0.053 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EAK87515.1 - 0.015 15.1 0.0 0.055 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAK87515.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Ribosomal_L23 PF00276.15 EAK87516.1 - 2.2e-17 62.7 5.0 2.2e-17 62.7 3.4 2.7 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 EAK87516.1 - 6.4e-15 54.9 12.1 1.3e-14 53.9 8.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain NPR3 PF03666.8 EAK87516.1 - 0.05 12.1 3.3 0.059 11.8 2.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RRM_5 PF13893.1 EAK87516.1 - 0.12 12.2 0.1 19 5.2 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EKR PF10371.4 EAK87518.1 - 0.097 12.2 0.0 0.64 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF4331 PF14224.1 EAK87520.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4331) zf-DNL PF05180.7 EAK87521.1 - 2.7e-24 84.6 5.0 5.4e-24 83.7 3.4 1.5 1 0 0 1 1 1 1 DNL zinc finger DUF164 PF02591.10 EAK87521.1 - 0.069 12.9 2.2 0.14 11.9 1.5 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain DUF3834 PF12916.2 EAK87521.1 - 0.085 11.8 0.4 0.19 10.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3834) Jiv90 PF14901.1 EAK87521.1 - 0.096 12.6 0.5 0.096 12.6 0.3 1.8 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone HNH_5 PF14279.1 EAK87521.1 - 0.81 9.7 7.3 2.5 8.1 4.3 2.3 1 1 1 2 2 2 0 HNH endonuclease DUF2039 PF10217.4 EAK87521.1 - 2.3 8.3 9.9 6.3 6.8 5.4 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) C1_1 PF00130.17 EAK87521.1 - 2.7 7.7 6.7 1.2 8.8 2.0 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C4_Topoisom PF01396.14 EAK87521.1 - 3.3 7.2 6.7 9.9 5.7 0.7 3.3 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger TRAM_LAG1_CLN8 PF03798.11 EAK87524.1 - 1.3e-26 93.3 16.1 1.3e-26 93.3 11.2 1.5 2 0 0 2 2 2 1 TLC domain LSM PF01423.17 EAK87525.1 - 1.1e-07 31.3 0.0 1.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAK87525.1 - 0.016 15.0 0.0 0.046 13.6 0.0 1.8 1 0 0 1 1 1 0 Ataxin 2 SM domain Flu_PB1 PF00602.12 EAK87525.1 - 0.029 12.1 0.1 0.031 12.0 0.1 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 Transposase_22 PF02994.9 EAK87525.1 - 0.045 12.2 2.2 0.051 12.0 1.5 1.2 1 1 0 1 1 1 0 L1 transposable element Ank_2 PF12796.2 EAK87526.1 - 4.7e-28 97.3 1.4 6.3e-14 52.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAK87526.1 - 2.1e-25 87.2 7.7 6e-07 28.9 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EAK87526.1 - 2e-23 82.3 7.7 1.6e-08 34.8 0.0 5.0 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAK87526.1 - 1.4e-20 72.8 5.5 4.1e-05 23.6 0.2 6.1 1 1 6 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAK87526.1 - 1.3e-16 58.9 9.1 0.00073 19.5 0.0 6.2 7 0 0 7 7 7 4 Ankyrin repeat DUF912 PF06024.7 EAK87526.1 - 0.0021 18.0 6.5 0.29 11.1 0.2 2.7 2 0 0 2 2 2 2 Nucleopolyhedrovirus protein of unknown function (DUF912) Ribosomal_S17e PF00833.13 EAK87527.1 - 1.2e-57 192.9 0.5 1.4e-57 192.7 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 DUF313 PF03754.8 EAK87527.1 - 0.58 10.1 2.3 2 8.3 1.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF313) DUF4602 PF15375.1 EAK87528.1 - 3.4e-08 33.6 13.9 6.9e-08 32.6 9.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) Ribosomal_L27 PF01016.14 EAK87528.1 - 0.036 13.8 1.5 0.05 13.3 0.2 1.8 2 0 0 2 2 2 0 Ribosomal L27 protein DUF2149 PF09919.4 EAK87528.1 - 0.068 13.2 0.9 0.14 12.3 0.3 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Acid_phosphat_B PF03767.9 EAK87528.1 - 0.17 11.2 4.5 0.26 10.6 3.1 1.5 1 1 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Ribosomal_L7Ae PF01248.21 EAK87529.1 - 9.2e-23 79.5 0.2 1.3e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.7 EAK87529.1 - 0.027 14.6 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding zf-HIT PF04438.11 EAK87530.1 - 2.1e-08 33.6 11.1 2.1e-08 33.6 7.7 2.0 3 0 0 3 3 3 1 HIT zinc finger Snf7 PF03357.16 EAK87531.1 - 5e-22 78.0 22.2 6.4e-22 77.7 15.4 1.2 1 0 0 1 1 1 1 Snf7 DUF285 PF03382.9 EAK87531.1 - 0.084 12.4 1.1 0.14 11.7 0.6 1.5 1 1 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 NAP PF00956.13 EAK87531.1 - 3.5 6.6 9.0 30 3.6 6.2 2.1 1 1 0 1 1 1 0 Nucleosome assembly protein (NAP) PKD_channel PF08016.7 EAK87532.1 - 0.013 14.0 0.8 0.022 13.1 0.5 1.3 1 0 0 1 1 1 0 Polycystin cation channel Mucin PF01456.12 EAK87532.1 - 0.12 12.1 19.5 0.19 11.4 13.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SNARE_assoc PF09335.6 EAK87533.1 - 8.1e-05 22.8 1.4 8.1e-05 22.8 1.0 2.8 3 0 0 3 3 3 1 SNARE associated Golgi protein ORMDL PF04061.9 EAK87533.1 - 0.017 14.7 0.3 0.017 14.7 0.2 2.5 2 1 0 2 2 2 0 ORMDL family Racemase_4 PF13615.1 EAK87533.1 - 0.023 14.9 0.4 0.49 10.6 0.0 2.8 3 0 0 3 3 3 0 Putative alanine racemase BSD PF03909.12 EAK87535.1 - 9.4e-26 89.3 0.0 1.5e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 BSD domain SWIM PF04434.12 EAK87536.1 - 0.096 12.1 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 SWIM zinc finger MutS_III PF05192.13 EAK87537.1 - 0.077 12.7 1.2 5.6 6.6 0.0 3.1 2 2 1 3 3 3 0 MutS domain III PsbU PF06514.6 EAK87537.1 - 1.8 8.4 9.9 9.3 6.1 0.2 3.7 2 2 0 3 3 3 0 Photosystem II 12 kDa extrinsic protein (PsbU) DCP1 PF06058.8 EAK87538.1 - 3e-32 111.2 1.2 3e-32 111.2 0.8 2.5 2 1 1 3 3 3 1 Dcp1-like decapping family DUF4298 PF14131.1 EAK87538.1 - 0.035 13.9 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) ANTH PF07651.11 EAK87538.1 - 0.044 12.4 3.4 0.072 11.7 2.3 1.5 1 1 0 1 1 1 0 ANTH domain NADH5_C PF06455.6 EAK87538.1 - 0.12 11.7 0.2 0.42 9.9 0.0 2.0 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus Eapp_C PF10238.4 EAK87538.1 - 0.32 10.8 13.3 0.69 9.8 8.7 2.0 1 1 0 1 1 1 0 E2F-associated phosphoprotein zf-rbx1 PF12678.2 EAK87539.1 - 0.081 13.0 4.8 1.4 9.0 3.5 2.7 1 1 1 2 2 2 0 RING-H2 zinc finger zf-RING_2 PF13639.1 EAK87539.1 - 0.13 12.0 4.7 0.57 10.0 3.4 2.1 1 1 0 1 1 1 0 Ring finger domain PH PF00169.24 EAK87540.1 - 0.0096 16.1 0.8 0.0096 16.1 0.5 3.0 2 1 0 2 2 2 1 PH domain EF-hand_7 PF13499.1 EAK87541.1 - 7.1e-21 74.1 7.3 2.3e-11 43.6 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EAK87541.1 - 1.5e-19 67.6 7.2 1.4e-05 24.0 1.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EAK87541.1 - 3.4e-17 60.7 7.8 2.1e-05 24.0 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EAK87541.1 - 3e-16 58.7 5.5 8.5e-08 31.7 0.0 4.2 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EAK87541.1 - 1.8e-14 52.3 11.8 9e-07 27.9 1.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 EAK87541.1 - 1.4e-05 24.7 2.5 0.12 12.1 0.1 3.1 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EAK87541.1 - 1.4e-05 24.9 0.7 0.022 14.6 0.1 3.7 2 2 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EAK87541.1 - 0.049 13.6 0.1 1.5 8.8 0.1 2.5 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 EAK87541.1 - 0.094 12.7 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand VCBS PF13517.1 EAK87541.1 - 0.25 11.7 1.6 29 5.1 0.8 2.7 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Plasmod_Pvs28 PF06247.6 EAK87542.1 - 0.011 15.3 0.3 0.015 14.9 0.2 1.2 1 0 0 1 1 1 0 Plasmodium ookinete surface protein Pvs28 Plasmod_dom_1 PF09715.5 EAK87543.1 - 1.6 8.6 7.8 0.78 9.7 0.2 3.0 3 0 0 3 3 3 0 Plasmodium protein of unknown function (Plasmod_dom_1) Abhydrolase_6 PF12697.2 EAK87544.1 - 3e-22 79.6 0.0 4.1e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAK87544.1 - 2e-14 53.5 0.0 3.4e-14 52.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAK87544.1 - 5e-06 26.2 0.0 8.9e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EAK87544.1 - 1.4e-05 24.8 0.0 3.5e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Putative lysophospholipase DUF676 PF05057.9 EAK87544.1 - 0.00022 20.6 0.2 0.00052 19.3 0.1 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.15 EAK87544.1 - 0.0017 17.8 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 EAK87544.1 - 0.0046 16.4 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EAK87544.1 - 0.019 14.2 0.0 0.064 12.5 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EAK87544.1 - 0.033 13.7 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EAK87544.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein Abhydro_lipase PF04083.11 EAK87544.1 - 0.066 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Ndr PF03096.9 EAK87544.1 - 0.083 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family Ran_BP1 PF00638.13 EAK87545.1 - 2.5e-39 134.1 3.3 3.8e-39 133.5 2.3 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EAK87545.1 - 0.047 13.4 4.1 0.23 11.2 2.9 2.1 1 1 0 1 1 1 0 WH1 domain zf-C3HC4_3 PF13920.1 EAK87546.1 - 1.3e-09 37.5 13.1 2.8e-09 36.4 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK87546.1 - 0.00041 20.3 13.5 0.00041 20.3 9.3 2.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK87546.1 - 0.01 15.5 14.1 0.036 13.7 9.8 2.0 1 0 0 1 1 1 0 zinc-RING finger domain MRAP PF15183.1 EAK87547.1 - 0.054 13.1 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family zf-C3HC4_3 PF13920.1 EAK87548.1 - 1.6e-09 37.2 4.1 3.3e-09 36.2 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK87548.1 - 4.8e-07 29.6 8.6 1.4e-06 28.2 6.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAK87548.1 - 0.00023 20.7 7.2 0.00074 19.1 5.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK87548.1 - 0.00076 19.1 7.4 0.0015 18.2 5.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EAK87548.1 - 0.0023 17.7 6.7 0.0075 16.0 4.6 2.0 1 0 0 1 1 1 1 Ring finger domain YdjO PF14169.1 EAK87548.1 - 0.025 14.0 0.3 0.1 12.0 0.1 2.2 2 0 0 2 2 2 0 Cold-inducible protein YdjO Nicastrin PF05450.10 EAK87550.1 - 0.13 11.5 0.4 8.4 5.5 0.1 2.3 2 0 0 2 2 2 0 Nicastrin Ins_P5_2-kin PF06090.7 EAK87551.1 - 6.1e-06 25.4 0.1 1.1e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase PilN PF05137.8 EAK87551.1 - 0.062 13.1 0.2 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Fimbrial assembly protein (PilN) Cnd1 PF12717.2 EAK87551.1 - 0.15 11.8 10.3 0.029 14.2 2.3 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 ApoL PF05461.6 EAK87552.1 - 0.011 15.0 0.5 0.011 15.0 0.3 1.6 1 1 1 2 2 2 0 Apolipoprotein L DUF2762 PF10960.3 EAK87552.1 - 0.49 10.1 7.3 0.095 12.4 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2762) Ndc1_Nup PF09531.5 EAK87552.1 - 6.2 5.1 11.0 7 4.9 7.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-U1 PF06220.7 EAK87555.1 - 1.3e-17 63.0 4.5 1.3e-17 63.0 3.1 2.0 2 0 0 2 2 2 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EAK87555.1 - 0.00055 20.0 4.4 0.0025 17.8 3.1 2.2 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding IMCp PF12314.3 EAK87556.1 - 5.4e-20 71.3 133.5 4.3e-11 42.8 16.3 6.4 1 1 5 6 6 6 5 Inner membrane complex protein Helicase_C PF00271.26 EAK87557.1 - 2.7e-12 46.3 0.0 9.5e-12 44.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EAK87557.1 - 3.9e-08 33.1 0.1 3.6e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EAK87557.1 - 1.1e-06 28.5 0.0 1.1e-06 28.5 0.0 3.4 3 1 0 3 3 2 1 Helicase associated domain (HA2) DEAD PF00270.24 EAK87557.1 - 5.8e-06 25.9 0.3 3.1e-05 23.5 0.2 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Daxx PF03344.10 EAK87557.1 - 2.4e-05 23.0 31.3 2.4e-05 23.0 21.7 2.5 2 1 0 2 2 1 1 Daxx Family NESP55 PF06390.7 EAK87557.1 - 0.00032 20.1 8.6 0.00032 20.1 6.0 2.6 3 0 0 3 3 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) AAA_22 PF13401.1 EAK87557.1 - 0.00093 19.3 0.1 0.0091 16.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain Trypan_PARP PF05887.6 EAK87557.1 - 0.0033 17.2 13.4 0.0033 17.2 9.3 3.1 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) T2SE PF00437.15 EAK87557.1 - 0.0081 15.0 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EAK87557.1 - 0.013 14.9 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EAK87557.1 - 0.046 13.6 0.1 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EAK87557.1 - 0.07 12.8 0.1 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 Part of AAA domain EF-hand_6 PF13405.1 EAK87559.1 - 0.00019 21.0 0.2 0.0019 17.9 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 EAK87559.1 - 0.00079 19.5 1.5 0.0017 18.4 1.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EAK87559.1 - 0.0014 18.1 0.6 0.018 14.6 0.4 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EAK87559.1 - 0.0053 15.9 0.1 0.054 12.8 0.0 2.4 2 0 0 2 2 2 1 EF hand Flag1_repress PF03614.8 EAK87559.1 - 0.065 12.8 0.1 0.098 12.2 0.1 1.2 1 0 0 1 1 1 0 Repressor of phase-1 flagellin CHD5 PF04420.9 EAK87560.1 - 0.0022 17.7 4.5 0.0032 17.1 2.9 1.5 1 1 0 1 1 1 1 CHD5-like protein DUF1184 PF06683.6 EAK87560.1 - 0.016 14.7 1.3 0.031 13.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) ABC2_membrane_2 PF12679.2 EAK87560.1 - 0.43 9.3 3.6 0.49 9.2 2.4 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4366 PF14283.1 EAK87561.1 - 0.042 13.2 0.2 0.07 12.5 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Ribosomal_L34 PF00468.12 EAK87561.1 - 0.048 13.3 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein L34 MARVEL PF01284.18 EAK87562.1 - 5.6 6.7 11.4 1.1 9.1 5.2 1.7 2 0 0 2 2 2 0 Membrane-associating domain PP2C PF00481.16 EAK87565.1 - 1.8e-47 161.9 0.0 3e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EAK87565.1 - 2.3e-06 27.1 0.0 1.2e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EAK87565.1 - 3e-06 27.0 0.0 1.5e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) HTH_39 PF14090.1 EAK87566.1 - 0.066 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain S_layer_N PF05123.7 EAK87566.1 - 0.46 10.0 5.5 1.1 8.8 3.8 1.6 1 0 0 1 1 1 0 S-layer like family, N-terminal region FAM60A PF15396.1 EAK87566.1 - 4.2 7.0 10.6 0.25 11.0 0.9 2.9 3 0 0 3 3 3 0 Protein Family FAM60A DUF1948 PF09185.5 EAK87567.1 - 0.13 11.9 1.8 6.8 6.3 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1948) Proteasome PF00227.21 EAK87568.1 - 9.4e-50 168.5 0.5 1.2e-49 168.1 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit CAP PF00188.21 EAK87568.1 - 0.026 14.9 0.1 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 Cysteine-rich secretory protein family Glyco_transf_92 PF01697.22 EAK87569.1 - 0.0063 15.8 0.7 0.012 14.9 0.5 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 92 Hexapep PF00132.19 EAK87569.1 - 0.0089 15.4 6.2 0.027 13.9 4.3 1.8 1 0 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) Gly-zipper_OmpA PF13436.1 EAK87569.1 - 0.031 13.9 5.4 0.08 12.6 3.7 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain HAD PF12710.2 EAK87569.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAK87569.1 - 0.2 11.8 1.0 9.1 6.4 0.3 2.2 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF3522 PF12036.3 EAK87570.1 - 3.9e-07 30.0 18.5 3.4e-06 26.9 12.8 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3522) EGF_2 PF07974.8 EAK87570.1 - 2.4 8.3 10.3 7.9 6.7 7.1 2.0 1 0 0 1 1 1 0 EGF-like domain DUF3844 PF12955.2 EAK87570.1 - 8.4 6.5 9.0 3.5 7.7 2.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3844) WD40 PF00400.27 EAK87574.1 - 1.8e-08 33.9 0.3 0.12 12.3 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EAK87574.1 - 0.016 14.6 0.0 0.086 12.2 0.0 2.1 2 0 0 2 2 2 0 PQQ-like domain TrbM PF07424.6 EAK87574.1 - 0.099 12.6 0.8 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 TrbM SNF2_N PF00176.18 EAK87577.1 - 4.3e-65 219.4 0.5 6.4e-65 218.8 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAK87577.1 - 2.6e-13 49.6 0.0 1.1e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Frataxin_Cyay PF01491.11 EAK87579.1 - 9.3e-17 60.8 0.1 1.3e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 Frataxin-like domain Methyltransf_18 PF12847.2 EAK87580.1 - 5.8e-17 62.2 0.0 8.2e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAK87580.1 - 2e-14 53.4 0.4 4.1e-14 52.4 0.3 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAK87580.1 - 4.2e-07 30.3 0.0 6.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAK87580.1 - 3e-06 27.0 0.0 6.1e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAK87580.1 - 6.9e-06 26.4 0.8 1.4e-05 25.4 0.1 1.9 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAK87580.1 - 9.5e-06 25.6 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAK87580.1 - 2.2e-05 23.8 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EAK87580.1 - 0.00023 21.4 0.0 0.00032 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EAK87580.1 - 0.00025 20.2 0.1 0.00039 19.5 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EAK87580.1 - 0.0012 18.0 0.1 0.0016 17.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 EAK87580.1 - 0.0012 18.0 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 EAK87580.1 - 0.0012 17.8 0.0 0.0042 16.1 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 EAK87580.1 - 0.0018 17.8 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_20 PF12147.3 EAK87580.1 - 0.0026 16.6 0.0 0.0031 16.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase DUF633 PF04816.7 EAK87580.1 - 0.0034 16.7 0.1 0.0092 15.3 0.0 1.7 1 1 1 2 2 2 1 Family of unknown function (DUF633) tRNA_U5-meth_tr PF05958.6 EAK87580.1 - 0.017 13.7 0.1 0.066 11.8 0.1 1.8 1 1 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_9 PF08003.6 EAK87580.1 - 0.032 12.9 0.0 0.044 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.7 EAK87580.1 - 0.034 13.5 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 EAK87580.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EAK87580.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Tox-REase-3 PF15647.1 EAK87581.1 - 0.054 13.2 0.2 0.072 12.8 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 Peptidase_S9 PF00326.16 EAK87584.1 - 8.7e-31 106.8 0.0 1.7e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAK87584.1 - 3.7e-11 42.9 0.0 5.8e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAK87584.1 - 7e-10 39.1 0.0 1.4e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EAK87584.1 - 5.5e-09 36.0 0.0 1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EAK87584.1 - 5e-05 22.6 0.0 0.00055 19.2 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EAK87584.1 - 0.0025 17.2 0.1 0.25 10.7 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EAK87584.1 - 0.025 14.1 0.0 0.13 11.8 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EAK87584.1 - 0.14 11.5 0.0 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Nup88 PF10168.4 EAK87585.1 - 0.0066 14.3 1.6 0.008 14.0 1.1 1.1 1 0 0 1 1 1 1 Nuclear pore component UPF0122 PF04297.9 EAK87585.1 - 0.29 11.1 4.5 0.076 13.0 0.6 1.9 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Pkinase PF00069.20 EAK87586.1 - 4.5e-21 75.1 3.1 2.8e-19 69.2 2.1 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK87586.1 - 4.3e-11 42.3 1.3 5.7e-07 28.8 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAK87586.1 - 5.5e-06 25.5 0.0 0.043 12.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EAK87586.1 - 0.0004 19.5 0.0 0.0007 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAK87586.1 - 0.072 12.8 0.0 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2361 PF10153.4 EAK87587.1 - 1.4e-07 31.6 14.8 1.4e-07 31.6 10.3 3.5 2 1 2 4 4 4 1 Uncharacterised conserved protein (DUF2361) UPF0020 PF01170.13 EAK87588.1 - 2.3e-18 66.4 0.0 1.3e-17 64.0 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EAK87588.1 - 2.1e-08 34.2 0.0 8.1e-08 32.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EAK87588.1 - 0.00016 21.2 1.4 0.0036 16.8 0.1 2.4 2 1 0 2 2 2 1 DNA methylase N6_Mtase PF02384.11 EAK87588.1 - 0.0016 17.6 0.0 0.025 13.6 0.0 2.2 2 0 0 2 2 2 1 N-6 DNA Methylase MethyltransfD12 PF02086.10 EAK87588.1 - 0.013 14.9 1.1 0.16 11.3 0.0 2.1 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Nse4-Nse3_bdg PF15412.1 EAK87590.1 - 0.19 11.6 0.8 11 5.9 0.1 2.6 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE TSP_1 PF00090.14 EAK87591.1 - 1.3e-25 89.2 34.9 5.9e-09 35.9 7.1 3.7 3 0 0 3 3 3 3 Thrombospondin type 1 domain EGF PF00008.22 EAK87591.1 - 0.00019 21.2 7.4 0.00019 21.2 5.1 3.1 3 1 0 3 3 3 1 EGF-like domain ATG_C PF09333.6 EAK87592.1 - 7.9e-05 22.7 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 EAK87593.1 - 1.6e-31 108.2 2.0 3.4e-31 107.2 0.3 2.2 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter WD40 PF00400.27 EAK87595.1 - 0.1 12.5 2.0 31 4.6 0.1 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat Hexapep PF00132.19 EAK87596.1 - 8.1e-12 44.0 11.1 3.3e-08 32.6 2.2 3.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EAK87596.1 - 0.00017 21.0 14.6 0.0039 16.7 3.3 3.4 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EAK87596.1 - 0.0083 14.7 0.3 0.012 14.2 0.2 1.2 1 0 0 1 1 1 1 L-fucokinase Osteopontin PF00865.13 EAK87596.1 - 0.23 10.6 21.8 0.33 10.1 15.1 1.3 1 0 0 1 1 1 0 Osteopontin DDHD PF02862.12 EAK87596.1 - 0.33 10.7 3.1 0.43 10.3 2.1 1.1 1 0 0 1 1 1 0 DDHD domain DUF2457 PF10446.4 EAK87596.1 - 0.94 8.1 28.0 1.2 7.8 19.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EAK87596.1 - 1 7.2 16.0 1.3 6.9 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 EAK87596.1 - 1.3 8.1 22.7 1.6 7.7 15.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 EAK87596.1 - 1.4 8.0 19.3 2.2 7.4 13.4 1.4 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.6 EAK87596.1 - 1.8 6.3 9.9 2.6 5.7 6.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Vfa1 PF08432.5 EAK87596.1 - 3.5 7.5 9.7 5 7.0 6.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 EAK87596.1 - 5.2 5.4 20.9 6.4 5.1 14.5 1.1 1 0 0 1 1 1 0 Daxx Family Methyltransf_18 PF12847.2 EAK87597.1 - 2e-10 41.2 0.0 6.2e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAK87597.1 - 8.7e-10 38.3 0.2 3.3e-09 36.5 0.2 2.0 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAK87597.1 - 9.8e-10 38.0 0.6 9.8e-10 38.0 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EAK87597.1 - 4.8e-06 26.0 0.1 9.8e-06 25.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain zf-C2H2_2 PF12756.2 EAK87597.1 - 1.5e-05 25.0 0.1 3.7e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Methyltransf_26 PF13659.1 EAK87597.1 - 1.5e-05 24.9 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAK87597.1 - 5.9e-05 23.4 0.0 0.00024 21.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAK87597.1 - 0.00016 21.9 0.0 0.00045 20.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAK87597.1 - 0.00033 20.4 0.0 0.0011 18.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EAK87597.1 - 0.00093 18.8 0.7 0.0022 17.6 0.5 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EAK87597.1 - 0.007 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_9 PF08003.6 EAK87597.1 - 0.011 14.3 0.0 0.032 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_3 PF01596.12 EAK87597.1 - 0.019 14.0 0.2 0.058 12.4 0.1 1.8 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_15 PF09445.5 EAK87597.1 - 0.026 14.1 0.1 0.079 12.5 0.1 1.8 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_16 PF10294.4 EAK87597.1 - 0.028 13.8 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 EAK87597.1 - 0.034 13.2 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EAK87597.1 - 0.041 14.3 0.3 0.74 10.3 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain PCMT PF01135.14 EAK87597.1 - 0.082 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Adaptin_N PF01602.15 EAK87598.1 - 1.4e-86 290.9 20.7 2.1e-85 287.0 14.4 2.1 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EAK87598.1 - 1.9e-22 79.7 7.1 6.6e-22 77.9 4.9 2.0 1 0 0 1 1 1 1 Adaptin C-terminal domain DEAD PF00270.24 EAK87599.1 - 1.1e-25 90.0 0.1 2.6e-21 75.8 0.0 2.6 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK87599.1 - 1.8e-12 46.9 1.4 2.1e-11 43.5 0.1 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain T2SE PF00437.15 EAK87599.1 - 0.11 11.3 1.7 0.26 10.1 1.2 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein TK PF00265.13 EAK87600.1 - 1.3e-52 177.9 0.9 1.5e-52 177.7 0.6 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_22 PF13401.1 EAK87600.1 - 0.0033 17.5 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Nup54 PF13874.1 EAK87601.1 - 2.9e-30 104.8 4.7 2.9e-30 104.8 3.3 3.0 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Abhydrolase_5 PF12695.2 EAK87602.1 - 4e-20 72.0 0.0 6.1e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAK87602.1 - 5e-08 33.0 0.0 0.00049 20.0 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EAK87602.1 - 7.8e-08 32.0 0.5 1.7e-06 27.6 0.4 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EAK87602.1 - 1.2e-05 24.9 1.6 0.03 13.8 0.0 2.7 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAK87602.1 - 0.0018 17.5 0.0 0.0018 17.5 0.0 2.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.13 EAK87602.1 - 0.0095 15.2 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 EAK87602.1 - 0.013 14.9 0.1 0.038 13.4 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) LIP PF03583.9 EAK87602.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase DUF2457 PF10446.4 EAK87602.1 - 3 6.4 12.2 4.4 5.9 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Brix PF04427.13 EAK87603.1 - 1.2e-37 129.4 1.0 2.1e-37 128.6 0.7 1.4 1 0 0 1 1 1 1 Brix domain SH3_8 PF13457.1 EAK87603.1 - 0.056 13.6 0.6 0.12 12.5 0.4 1.5 1 0 0 1 1 1 0 SH3-like domain Prenyltransf PF01255.14 EAK87604.1 - 2.1e-59 200.3 0.9 2.6e-59 200.0 0.7 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4065 PF13274.1 EAK87605.1 - 0.39 11.4 5.0 0.32 11.6 2.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4065) DUF2951 PF11166.3 EAK87605.1 - 2.2 8.2 8.5 3.8 7.4 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Ly49 PF08391.5 EAK87607.1 - 0.0034 17.4 1.5 0.0045 17.1 1.0 1.1 1 0 0 1 1 1 1 Ly49-like protein, N-terminal region Phage_HK97_TLTM PF06120.6 EAK87607.1 - 0.01 15.2 0.1 0.011 15.1 0.1 1.1 1 0 0 1 1 1 1 Tail length tape measure protein Peptidase_S49_N PF08496.5 EAK87607.1 - 0.01 15.6 2.4 0.013 15.2 1.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2500 PF10694.4 EAK87607.1 - 0.011 15.7 0.2 0.016 15.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) IncA PF04156.9 EAK87607.1 - 0.044 13.3 0.6 0.063 12.8 0.4 1.2 1 0 0 1 1 1 0 IncA protein DUF3513 PF12026.3 EAK87607.1 - 0.053 13.0 4.7 0.072 12.6 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Fijivirus_P9-2 PF06837.6 EAK87607.1 - 0.071 12.2 0.0 0.086 11.9 0.0 1.1 1 0 0 1 1 1 0 Fijivirus P9-2 protein SID-1_RNA_chan PF13965.1 EAK87607.1 - 0.13 10.4 1.2 0.13 10.3 0.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Sec62 PF03839.11 EAK87607.1 - 0.13 11.6 3.2 0.16 11.3 2.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 MLANA PF14991.1 EAK87607.1 - 0.26 11.3 3.2 1.7 8.6 2.2 2.0 1 1 0 1 1 1 0 Protein melan-A DUF4366 PF14283.1 EAK87607.1 - 1.6 8.1 7.6 8.7 5.7 4.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) DUF3959 PF13105.1 EAK87607.1 - 4.8 6.4 7.1 11 5.2 4.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3959) Conotoxin PF02950.12 EAK87607.1 - 8.3 7.2 7.1 31 5.4 0.0 2.3 1 1 1 2 2 2 0 Conotoxin TAP42 PF04177.7 EAK87609.1 - 2.4e-43 148.4 19.2 2.9e-43 148.1 13.3 1.0 1 0 0 1 1 1 1 TAP42-like family N2227 PF07942.7 EAK87610.1 - 9.7e-95 316.5 0.3 1.6e-94 315.9 0.2 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.7 EAK87610.1 - 7.6e-05 23.1 1.9 0.14 12.6 0.0 3.5 3 0 0 3 3 3 2 Methyltransferase domain ABC_tran PF00005.22 EAK87612.1 - 1.9e-11 44.4 0.0 8.1e-09 35.8 0.0 3.0 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.1 EAK87612.1 - 0.0019 18.4 4.0 0.037 14.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EAK87612.1 - 0.0019 19.0 0.1 0.015 16.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EAK87612.1 - 0.025 14.2 0.2 0.059 13.0 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EAK87612.1 - 0.035 13.7 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EAK87612.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 EAK87612.1 - 0.69 9.4 0.0 1.2 8.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pyrophosphatase PF00719.14 EAK87613.1 - 3.4e-48 163.0 0.0 4.8e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase ABC_tran PF00005.22 EAK87614.1 - 4.7e-09 36.6 6.4 1.9e-06 28.2 2.3 4.0 3 1 0 3 3 3 2 ABC transporter AAA_18 PF13238.1 EAK87614.1 - 0.003 17.8 4.8 0.2 11.9 0.2 3.8 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EAK87614.1 - 0.0037 18.0 0.3 0.026 15.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain zf-C3HC4_3 PF13920.1 EAK87615.1 - 3.1e-13 49.1 9.4 5.2e-13 48.4 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK87615.1 - 1.4e-05 25.0 15.0 3e-05 23.9 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAK87615.1 - 0.00017 21.3 13.2 0.00031 20.5 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 EAK87615.1 - 0.0017 17.8 4.5 0.0017 17.8 3.1 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 DUF3567 PF12091.3 EAK87615.1 - 0.016 15.1 0.1 0.043 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) AMPKBI PF04739.10 EAK87615.1 - 0.017 14.9 1.2 0.017 14.9 0.8 3.5 2 1 1 3 3 3 0 5'-AMP-activated protein kinase beta subunit, interation domain DUF726 PF05277.7 EAK87616.1 - 3.6e-87 292.4 1.1 6.4e-87 291.6 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.7 EAK87616.1 - 6e-05 22.4 0.1 0.00012 21.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.17 EAK87616.1 - 7.1e-05 22.6 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 EAK87616.1 - 0.062 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.2 EAK87616.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family IBV_3A PF03617.8 EAK87616.1 - 1.8 8.3 6.8 0.23 11.2 1.2 2.3 2 0 0 2 2 2 0 IBV 3A protein Gly-zipper_Omp PF13488.1 EAK87617.1 - 0.00042 19.8 5.2 0.00071 19.1 3.6 1.3 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_OmpA PF13436.1 EAK87617.1 - 0.0033 17.0 1.7 0.0066 16.1 1.2 1.5 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EAK87617.1 - 0.21 11.1 8.5 0.35 10.4 5.9 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rtf2 PF04641.7 EAK87619.1 - 1.2e-06 27.9 0.0 1.5e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger DUF3611 PF12263.3 EAK87619.1 - 0.11 11.8 0.3 6.5 6.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Myb_DNA-binding PF00249.26 EAK87620.1 - 0.044 13.8 0.1 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain Ribosomal_L28e PF01778.12 EAK87622.1 - 1.2e-26 93.3 8.5 1.4e-26 93.1 5.9 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family PuR_N PF09182.5 EAK87622.1 - 0.0013 18.3 0.4 0.62 9.7 0.1 2.2 1 1 1 2 2 2 2 Bacterial purine repressor, N-terminal RRS1 PF04939.7 EAK87623.1 - 1.1e-47 161.5 3.9 1.1e-47 161.5 2.7 1.9 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) KH_1 PF00013.24 EAK87624.1 - 1e-06 28.2 0.0 2.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EAK87624.1 - 0.00042 19.8 0.2 0.0011 18.5 0.1 1.8 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EAK87624.1 - 0.014 15.1 5.4 0.71 9.6 0.5 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EAK87624.1 - 0.028 14.3 1.5 0.028 14.3 1.1 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 EAK87624.1 - 0.039 13.4 1.1 0.11 12.0 0.8 1.7 1 0 0 1 1 1 0 Zinc knuckle KH_2 PF07650.12 EAK87624.1 - 0.071 12.6 1.0 0.9 9.1 0.0 2.5 2 0 0 2 2 2 0 KH domain zf-CCHC_4 PF14392.1 EAK87624.1 - 0.23 11.1 7.2 0.89 9.2 0.6 2.8 2 0 0 2 2 2 0 Zinc knuckle DUF4366 PF14283.1 EAK87625.1 - 0.027 13.9 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Orthopox_B11R PF07033.6 EAK87625.1 - 0.051 13.0 0.2 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus B11R protein MMS22L_N PF14910.1 EAK87625.1 - 0.093 10.9 2.9 0.11 10.7 2.0 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal UFD1 PF03152.9 EAK87627.1 - 5.8e-78 260.0 0.0 7.6e-78 259.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EAK87627.1 - 0.02 14.5 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 DERM PF14704.1 EAK87627.1 - 0.021 14.7 0.6 0.032 14.1 0.4 1.3 1 0 0 1 1 1 0 Dermatopontin DUF1735 PF08522.5 EAK87627.1 - 0.024 15.0 0.7 0.092 13.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1735) AAA PF00004.24 EAK87628.1 - 1.1e-42 145.3 0.0 4.5e-42 143.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EAK87628.1 - 1.6e-07 31.3 0.0 4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EAK87628.1 - 2e-06 28.0 0.5 0.00027 21.0 0.1 2.8 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EAK87628.1 - 1.5e-05 24.1 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EAK87628.1 - 2.5e-05 24.0 0.2 0.00018 21.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EAK87628.1 - 2.5e-05 23.3 0.0 4.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EAK87628.1 - 4.5e-05 23.5 0.0 0.00021 21.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EAK87628.1 - 0.00032 21.5 0.1 0.00098 19.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EAK87628.1 - 0.00089 19.1 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EAK87628.1 - 0.00092 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EAK87628.1 - 0.0015 18.2 0.3 0.0029 17.3 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EAK87628.1 - 0.0023 17.3 1.2 0.18 11.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EAK87628.1 - 0.0026 17.6 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAK87628.1 - 0.0029 17.9 0.1 0.0092 16.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EAK87628.1 - 0.0041 17.0 0.1 0.009 15.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 EAK87628.1 - 0.0052 15.5 0.0 0.0093 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 EAK87628.1 - 0.0066 16.6 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EAK87628.1 - 0.007 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EAK87628.1 - 0.0076 15.9 0.0 0.22 11.1 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_24 PF13479.1 EAK87628.1 - 0.011 15.3 0.1 0.03 13.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EAK87628.1 - 0.015 14.5 0.1 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EAK87628.1 - 0.027 13.5 0.2 0.7 8.9 0.0 2.3 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 EAK87628.1 - 0.029 13.5 0.1 0.086 12.0 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.6 EAK87628.1 - 0.03 13.9 0.0 0.096 12.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EAK87628.1 - 0.031 13.1 0.0 0.051 12.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 EAK87628.1 - 0.063 12.9 0.1 0.36 10.4 0.0 2.1 2 1 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 EAK87628.1 - 0.099 12.9 0.0 0.39 10.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.21 EAK87628.1 - 0.1 12.0 0.0 0.77 9.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.10 EAK87628.1 - 0.1 12.3 0.0 0.53 10.0 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 EAK87628.1 - 0.1 12.2 0.8 1.1 8.9 0.1 2.7 2 1 0 2 2 2 0 NTPase Parvo_NS1 PF01057.12 EAK87628.1 - 0.13 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Lactamase_B_2 PF12706.2 EAK87629.1 - 0.00097 18.7 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain YMF19 PF02326.10 EAK87630.1 - 1.8 9.1 8.0 0.5 10.9 3.1 2.0 2 1 0 2 2 2 0 Plant ATP synthase F0 Thioredoxin PF00085.15 EAK87631.1 - 1.8e-32 111.0 0.2 1.4e-20 72.9 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.1 EAK87631.1 - 8.2e-08 32.4 1.9 0.007 16.5 0.0 3.9 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EAK87631.1 - 7.1e-07 29.2 2.6 0.061 13.4 0.0 4.6 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EAK87631.1 - 2.2e-06 27.2 0.0 0.0017 17.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.1 EAK87631.1 - 8.5e-05 22.5 0.0 0.041 13.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Glutaredoxin PF00462.19 EAK87631.1 - 0.0093 15.9 1.5 4.2 7.4 0.0 3.7 3 0 0 3 3 3 1 Glutaredoxin Bud13 PF09736.4 EAK87632.1 - 3e-35 121.6 7.1 3.8e-35 121.2 4.9 1.1 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex Lactamase_B_2 PF12706.2 EAK87633.1 - 7.3e-17 61.5 0.0 9.7e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EAK87633.1 - 7e-06 25.8 0.0 1.5e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily AP2 PF00847.15 EAK87634.1 - 4.6e-27 93.9 13.6 1e-15 57.5 1.9 4.1 5 0 0 5 5 5 3 AP2 domain DUF3595 PF12166.3 EAK87636.1 - 0.08 11.7 7.5 0.11 11.3 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DUF572 PF04502.8 EAK87637.1 - 0.019 14.2 35.5 0.011 15.0 16.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) Ctr PF04145.10 EAK87637.1 - 0.17 11.8 4.4 0.18 11.8 1.2 2.5 2 0 0 2 2 2 0 Ctr copper transporter family CDC45 PF02724.9 EAK87637.1 - 0.29 9.1 34.2 0.012 13.6 17.9 2.2 2 0 0 2 2 2 0 CDC45-like protein Zip PF02535.17 EAK87637.1 - 2.4 7.0 5.2 4.8 6.0 3.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Serglycin PF04360.7 EAK87638.1 - 0.016 14.9 0.4 0.016 14.9 0.3 2.4 3 0 0 3 3 3 0 Serglycin DUF2370 PF10176.4 EAK87638.1 - 0.28 10.4 5.7 7.1 5.8 1.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Menin PF05053.8 EAK87639.1 - 6.5 4.8 10.0 7.3 4.6 6.9 1.0 1 0 0 1 1 1 0 Menin Pkinase PF00069.20 EAK87640.1 - 5.1e-27 94.6 0.0 8.2e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK87640.1 - 3.8e-18 65.4 0.0 5.6e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1084 PF06454.6 EAK87641.1 - 0.01 14.9 17.2 0.12 11.3 7.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1084) MCM PF00493.18 EAK87642.1 - 3.8e-127 423.6 0.1 6.5e-127 422.8 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EAK87642.1 - 6.7e-17 62.0 1.4 6.7e-17 62.0 0.9 2.5 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EAK87642.1 - 4.3e-09 35.8 0.2 9.9e-06 24.8 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EAK87642.1 - 1.1e-05 25.1 0.0 2.4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAK87642.1 - 3.5e-05 23.5 0.0 0.00015 21.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Cut8_N PF14482.1 EAK87642.1 - 0.0024 17.8 1.4 0.0058 16.6 1.0 1.7 1 0 0 1 1 1 1 Cut8 proteasome-binding domain Sigma54_activat PF00158.21 EAK87642.1 - 0.033 13.6 0.3 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.1 EAK87642.1 - 0.35 10.8 1.9 5.4 6.9 0.0 3.3 3 2 1 4 4 4 0 AAA ATPase domain WD40 PF00400.27 EAK87643.1 - 4.2e-23 80.3 11.0 4.1e-08 32.8 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EAK87643.1 - 0.00028 19.1 0.2 0.27 9.3 0.1 3.5 2 2 2 4 4 4 2 Nucleoporin Nup120/160 DUF4557 PF15101.1 EAK87644.1 - 0.11 12.3 4.1 0.04 13.7 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Inos-1-P_synth PF01658.12 EAK87644.1 - 2.5 7.9 6.5 0.65 9.8 0.2 2.7 3 0 0 3 3 3 0 Myo-inositol-1-phosphate synthase PAP_central PF04928.12 EAK87645.1 - 1.9e-109 364.3 2.0 2.5e-109 363.9 0.0 1.9 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EAK87645.1 - 1.2e-42 145.0 0.1 1.2e-42 145.0 0.1 2.0 2 1 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EAK87645.1 - 3.8e-05 23.9 0.0 0.0001 22.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain His_Phos_2 PF00328.17 EAK87646.1 - 3.2e-28 99.0 4.1 4.3e-28 98.6 2.8 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.17 EAK87647.1 - 6.1e-27 94.8 1.5 8.8e-27 94.3 1.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Phasin_2 PF09361.5 EAK87647.1 - 0.065 13.2 0.1 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Phasin protein WD40 PF00400.27 EAK87648.1 - 6.1e-56 184.4 32.7 4.6e-09 35.8 0.3 10.3 9 1 0 9 9 9 9 WD domain, G-beta repeat Utp13 PF08625.6 EAK87648.1 - 7.8e-32 109.8 7.5 1.8e-31 108.6 5.2 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ZZ PF00569.12 EAK87649.1 - 2.1e-09 36.7 9.2 3.9e-09 35.9 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EAK87649.1 - 1e-07 31.8 6.6 2e-07 30.9 0.2 3.7 2 2 1 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAK87649.1 - 8.5e-06 25.7 1.0 0.0001 22.3 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain MF_alpha_N PF05436.6 EAK87649.1 - 0.038 13.6 0.2 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus WWE PF02825.15 EAK87651.1 - 1.3e-07 30.9 0.5 3.8e-07 29.4 0.3 1.8 1 0 0 1 1 1 1 WWE domain Ribosomal_L24e PF01246.15 EAK87654.1 - 1.4e-20 72.8 0.6 1.4e-20 72.8 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e WD40 PF00400.27 EAK87655.1 - 4.6e-27 92.8 13.2 1.5e-07 30.9 1.7 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF3312 PF11768.3 EAK87655.1 - 0.00014 20.2 0.1 0.00029 19.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) UDPGP PF01704.13 EAK87656.1 - 5.2e-29 100.9 10.5 8.6e-29 100.2 7.2 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Yip1 PF04893.12 EAK87657.1 - 5.5e-08 32.5 12.1 8.8e-08 31.8 8.4 1.2 1 0 0 1 1 1 1 Yip1 domain DNA_topoisoIV PF00521.15 EAK87659.1 - 5e-120 401.2 7.2 5.2e-83 279.2 0.0 3.0 2 1 1 3 3 3 2 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EAK87659.1 - 1.4e-29 102.4 0.4 7.5e-29 100.1 0.3 2.3 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EAK87659.1 - 2.7e-12 46.5 0.0 3.6e-11 42.9 0.0 3.2 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EAK87659.1 - 1.1e-07 31.5 0.0 3.1e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kazal_2 PF07648.10 EAK87660.1 - 4.4e-44 148.1 42.8 1.9e-08 34.1 0.3 7.7 7 0 0 7 7 7 7 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EAK87660.1 - 3.9e-36 122.8 66.6 8.3e-09 35.3 0.2 8.3 8 0 0 8 8 8 7 Kazal-type serine protease inhibitor domain RRM_6 PF14259.1 EAK87661.1 - 6.2e-08 32.5 0.1 3.2e-07 30.2 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAK87661.1 - 1.4e-06 27.8 0.0 0.0029 17.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK87661.1 - 0.00015 21.5 0.0 0.3 10.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nbl1_Borealin_N PF10444.4 EAK87661.1 - 0.27 10.6 2.3 0.85 9.0 0.1 2.6 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal AAA_18 PF13238.1 EAK87661.1 - 0.66 10.2 3.5 0.66 10.2 0.2 2.2 1 1 0 2 2 2 0 AAA domain POR_N PF01855.14 EAK87662.1 - 1.3e-68 230.9 0.2 3.8e-68 229.4 0.2 1.7 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FAD_binding_1 PF00667.15 EAK87662.1 - 5.1e-34 117.6 0.0 1.2e-33 116.4 0.0 1.6 2 0 0 2 2 1 1 FAD binding domain POR PF01558.13 EAK87662.1 - 7e-27 94.4 0.0 1.3e-26 93.5 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Flavodoxin_1 PF00258.20 EAK87662.1 - 2.9e-26 92.2 0.1 6.7e-26 90.9 0.1 1.7 1 0 0 1 1 1 1 Flavodoxin EKR PF10371.4 EAK87662.1 - 9.4e-25 85.9 0.1 3.5e-24 84.1 0.1 2.0 2 0 0 2 2 1 1 Domain of unknown function NAD_binding_1 PF00175.16 EAK87662.1 - 2e-12 47.6 0.2 9.6e-12 45.4 0.0 2.4 2 0 0 2 2 1 1 Oxidoreductase NAD-binding domain Fer4_7 PF12838.2 EAK87662.1 - 1.5e-09 38.0 6.3 1.5e-09 38.0 4.4 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.22 EAK87662.1 - 1.8e-09 36.8 19.2 1.3e-05 24.5 2.2 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.1 EAK87662.1 - 1.9e-09 37.6 5.0 0.00058 20.0 0.7 3.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain TPP_enzyme_C PF02775.16 EAK87662.1 - 1.5e-08 34.3 0.1 4.8e-08 32.7 0.0 1.9 2 0 0 2 2 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_16 PF13484.1 EAK87662.1 - 6.9e-08 33.1 6.0 0.0027 18.4 0.7 3.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 EAK87662.1 - 7.5e-08 32.0 8.6 5.6e-06 26.0 6.5 2.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 EAK87662.1 - 2.4e-07 30.5 11.4 3.9e-06 26.6 8.0 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 EAK87662.1 - 6.1e-07 29.3 5.4 6.1e-07 29.3 3.7 2.2 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 EAK87662.1 - 3.4e-06 27.3 3.2 3.4e-06 27.3 2.2 2.5 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EAK87662.1 - 8.6e-05 22.2 24.6 0.00051 19.7 3.6 3.3 3 0 0 3 3 2 2 4Fe-4S binding domain Transketolase_C PF02780.15 EAK87662.1 - 0.0052 16.7 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Flavodoxin_5 PF12724.2 EAK87662.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Fer4_15 PF13459.1 EAK87662.1 - 0.016 15.7 4.8 0.4 11.2 0.1 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_13 PF13370.1 EAK87662.1 - 0.12 12.7 9.9 1.3 9.4 0.4 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_4 PF12800.2 EAK87662.1 - 0.31 11.5 21.8 0.043 14.1 0.9 3.5 4 0 0 4 4 2 0 4Fe-4S binding domain DUF849 PF05853.7 EAK87662.1 - 0.42 9.4 0.0 0.76 8.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) Fer4_18 PF13746.1 EAK87662.1 - 0.5 10.8 13.5 0.47 10.9 5.3 3.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EAK87662.1 - 1.2 9.1 29.9 0.017 15.0 2.4 3.6 4 0 0 4 4 2 0 4Fe-4S binding domain Tme5_EGF_like PF09064.5 EAK87664.1 - 0.17 11.5 0.1 0.17 11.5 0.0 10.6 11 2 2 13 13 13 0 Thrombomodulin like fifth domain, EGF-like cEGF PF12662.2 EAK87664.1 - 2.8 7.6 32.1 6.8 6.4 0.3 9.4 9 0 0 9 9 9 0 Complement Clr-like EGF-like DUF3591 PF12157.3 EAK87665.1 - 5.7e-26 90.9 0.2 9.8e-08 30.8 0.0 5.4 3 2 0 3 3 3 3 Protein of unknown function (DUF3591) Bromodomain PF00439.20 EAK87665.1 - 4.7e-14 52.0 0.1 1.5e-13 50.4 0.1 1.9 1 0 0 1 1 1 1 Bromodomain zf-CCHC_6 PF15288.1 EAK87665.1 - 0.00072 19.1 0.9 0.0017 17.9 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EAK87665.1 - 0.003 17.4 0.4 0.0065 16.3 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle fn3 PF00041.16 EAK87666.1 - 4.6e-08 33.0 0.0 6.2e-06 26.2 0.0 3.2 2 0 0 2 2 2 2 Fibronectin type III domain ATP_bind_4 PF01902.12 EAK87667.1 - 7.4e-32 110.4 0.0 1.8e-31 109.2 0.0 1.6 1 1 0 1 1 1 1 ATP-binding region Ribonuc_2-5A PF06479.7 EAK87667.1 - 0.0089 15.8 0.7 7.4 6.4 0.0 3.3 3 0 0 3 3 3 2 Ribonuclease 2-5A AP2 PF00847.15 EAK87668.1 - 2.1e-07 30.9 0.2 7.5e-07 29.2 0.1 2.1 2 0 0 2 2 2 1 AP2 domain NTF2 PF02136.15 EAK87669.1 - 1.4e-33 115.7 0.2 1.6e-33 115.5 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain EPL1 PF10513.4 EAK87670.1 - 9.6e-20 71.4 0.1 2.4e-19 70.1 0.1 1.7 1 0 0 1 1 1 1 Enhancer of polycomb-like RAP1 PF07218.6 EAK87670.1 - 0.13 10.3 2.4 0.28 9.2 1.7 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-AD PF07776.10 EAK87672.1 - 0.018 15.0 0.4 0.064 13.2 0.2 2.0 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) DivIC PF04977.10 EAK87672.1 - 0.3 10.5 5.6 24 4.5 3.2 2.6 2 0 0 2 2 2 0 Septum formation initiator Pox_polyA_pol_N PF12630.2 EAK87672.1 - 0.33 11.0 4.6 1.7 8.7 1.0 2.6 1 1 1 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain Prefoldin_2 PF01920.15 EAK87672.1 - 5.2 6.8 10.3 0.59 9.9 1.3 3.1 3 0 0 3 3 3 0 Prefoldin subunit SAP PF02037.22 EAK87673.1 - 0.012 15.1 0.0 0.032 13.7 0.0 1.8 2 0 0 2 2 2 0 SAP domain UIM PF02809.15 EAK87674.1 - 0.0022 17.4 3.8 0.51 10.0 0.2 3.0 2 0 0 2 2 2 2 Ubiquitin interaction motif V-ATPase_C PF03223.10 EAK87675.1 - 8.2e-112 373.7 5.8 9.5e-112 373.5 4.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C FANCI_S3 PF14677.1 EAK87675.1 - 0.0015 17.9 1.0 0.062 12.6 0.0 3.2 3 1 0 3 3 3 1 FANCI solenoid 3 RmuC PF02646.11 EAK87675.1 - 0.31 9.8 4.8 1.6 7.4 0.1 2.8 3 0 0 3 3 3 0 RmuC family DUF948 PF06103.6 EAK87675.1 - 0.4 10.5 2.1 8.3 6.3 0.1 3.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3437 PF11919.3 EAK87677.1 - 7e-22 76.9 0.0 4.5e-21 74.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) CK2S PF15011.1 EAK87677.1 - 0.43 10.3 5.7 2.9 7.6 0.1 3.0 3 0 0 3 3 3 0 Casein Kinase 2 substrate XPG_N PF00752.12 EAK87678.1 - 2.2e-27 95.2 0.0 7.2e-27 93.6 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EAK87678.1 - 2e-24 85.4 0.5 1.9e-23 82.3 0.0 3.1 2 1 1 3 3 3 1 XPG I-region Trypan_PARP PF05887.6 EAK87678.1 - 3.3e-05 23.7 27.9 3.3e-05 23.7 19.4 2.7 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) 5_3_exonuc PF01367.15 EAK87678.1 - 8.3e-05 22.7 4.1 0.037 14.2 0.0 3.8 3 0 0 3 3 3 2 5'-3' exonuclease, C-terminal SAM fold ORC5_C PF14630.1 EAK87679.1 - 1.7e-22 80.1 0.0 3.2e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus NADH_dh_m_C1 PF15088.1 EAK87680.1 - 0.007 15.8 0.6 0.019 14.4 0.1 2.0 2 0 0 2 2 2 1 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial MFS_1 PF07690.11 EAK87681.1 - 1.9e-23 82.7 39.0 1.5e-17 63.4 5.8 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF912 PF06024.7 EAK87681.1 - 0.026 14.5 0.7 0.026 14.5 0.5 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Spore_GerAC PF05504.6 EAK87681.1 - 0.083 12.6 8.0 0.13 12.0 5.6 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal HEAT_2 PF13646.1 EAK87682.1 - 1.8e-21 76.1 0.7 1.4e-11 44.4 0.0 3.0 2 1 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.11 EAK87682.1 - 1.2e-11 43.8 0.0 0.2 12.2 0.0 5.7 5 0 0 5 5 5 3 PBS lyase HEAT-like repeat HEAT PF02985.17 EAK87682.1 - 3.3e-08 32.9 0.4 0.6 10.3 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EAK87682.1 - 0.00033 21.0 0.2 4.2 7.9 0.0 4.8 4 2 2 6 6 6 2 HEAT-like repeat Cohesin_HEAT PF12765.2 EAK87682.1 - 0.007 16.2 0.0 0.032 14.1 0.0 2.1 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion IBN_N PF03810.14 EAK87682.1 - 0.066 13.1 1.4 7.1 6.6 0.1 3.7 4 0 0 4 4 4 0 Importin-beta N-terminal domain TPR_11 PF13414.1 EAK87683.1 - 2e-11 43.3 0.4 1.7e-09 37.1 0.1 2.8 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EAK87683.1 - 4.8e-11 41.7 1.5 0.00018 20.9 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAK87683.1 - 5.6e-10 38.3 0.4 0.00022 20.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAK87683.1 - 1.3e-05 24.5 11.4 0.033 13.9 0.3 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAK87683.1 - 0.0021 18.7 0.0 0.0051 17.4 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAK87683.1 - 0.0025 17.7 0.1 5.9 6.8 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EAK87683.1 - 0.065 13.7 0.5 2.8 8.5 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAK87683.1 - 0.08 13.2 0.0 0.3 11.4 0.0 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat SET PF00856.23 EAK87684.1 - 5.4e-13 49.5 0.5 5.4e-13 49.5 0.4 2.5 3 1 0 3 3 3 1 SET domain Mit_KHE1 PF10173.4 EAK87684.1 - 0.04 13.7 1.4 0.084 12.7 1.0 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related TPR_2 PF07719.12 EAK87685.1 - 8.7e-17 59.6 2.0 0.0075 16.1 0.0 7.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAK87685.1 - 1e-13 50.6 2.8 0.00014 21.4 0.0 6.8 6 1 0 6 6 6 2 TPR repeat TPR_1 PF00515.23 EAK87685.1 - 6.9e-12 44.4 7.6 0.005 16.3 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EAK87685.1 - 2.5e-10 40.1 0.0 0.027 14.9 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAK87685.1 - 4.3e-08 32.9 5.6 0.49 10.3 0.0 6.1 5 1 0 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EAK87685.1 - 1e-05 25.5 11.1 0.35 11.0 0.0 6.0 3 2 3 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EAK87685.1 - 4.9e-05 23.6 0.0 0.02 15.4 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAK87685.1 - 0.001 18.6 7.5 0.5 10.2 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAK87685.1 - 0.0033 17.4 0.7 2.6 8.4 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAK87685.1 - 0.0073 16.0 0.9 12 5.9 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAK87685.1 - 0.0079 16.5 0.0 18 5.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAK87685.1 - 0.0093 16.6 0.0 6.2 7.6 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat AAA_14 PF13173.1 EAK87685.1 - 4.2 7.2 7.1 1.4 8.8 0.1 3.3 4 0 0 4 4 4 0 AAA domain TBCC PF07986.7 EAK87687.1 - 2e-15 56.2 7.7 3.7e-15 55.3 5.3 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.6 EAK87687.1 - 1.8e-05 24.1 1.9 5.5e-05 22.5 1.3 1.8 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Abhydrolase_3 PF07859.8 EAK87688.1 - 1.1e-36 126.4 0.0 1.3e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EAK87688.1 - 2.3e-08 33.1 0.0 1.8e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family DUF2424 PF10340.4 EAK87688.1 - 0.00039 19.1 0.1 0.0011 17.7 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EAK87688.1 - 0.0085 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAK87688.1 - 0.059 12.5 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family CBFD_NFYB_HMF PF00808.18 EAK87689.1 - 2.3e-12 46.7 0.0 4.6e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EAK87689.1 - 3.2e-07 30.3 0.0 5.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF1064 PF06356.6 EAK87689.1 - 0.015 15.2 0.0 0.043 13.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) TAF PF02969.12 EAK87689.1 - 0.025 14.5 0.0 0.073 13.0 0.0 1.8 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TFIID_20kDa PF03847.8 EAK87689.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A PH_BEACH PF14844.1 EAK87689.1 - 0.9 9.4 0.1 0.9 9.4 0.0 3.0 3 1 1 4 4 4 0 PH domain associated with Beige/BEACH TUDOR PF00567.19 EAK87690.1 - 4.9e-07 29.6 0.0 1.2e-05 25.1 0.0 2.7 2 1 1 3 3 3 1 Tudor domain G-7-MTase PF12803.2 EAK87690.1 - 0.15 11.2 5.4 0.26 10.3 3.7 1.3 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) SH3_3 PF08239.6 EAK87690.1 - 0.26 11.5 1.3 0.75 10.0 0.1 2.4 3 0 0 3 3 3 0 Bacterial SH3 domain DASH_Dad3 PF08656.5 EAK87690.1 - 1 9.0 7.1 0.071 12.8 1.2 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 mRNA_cap_C PF03919.10 EAK87690.1 - 1.8 8.9 12.4 3.9 7.8 0.2 2.7 2 2 0 2 2 2 0 mRNA capping enzyme, C-terminal domain SMN PF06003.7 EAK87690.1 - 3.1 6.8 6.7 0.22 10.6 0.2 2.0 1 1 0 2 2 2 0 Survival motor neuron protein (SMN) DUF2042 PF09743.4 EAK87691.1 - 2.7e-78 263.0 19.6 2.7e-78 263.0 13.6 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2042) HTH_24 PF13412.1 EAK87691.1 - 0.0017 17.6 1.0 0.013 14.9 0.1 3.0 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding FeoC PF09012.5 EAK87691.1 - 0.048 13.3 0.3 0.12 12.0 0.2 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_11 PF08279.7 EAK87691.1 - 0.075 12.6 1.1 0.3 10.7 0.1 2.4 2 0 0 2 2 2 0 HTH domain WD40 PF00400.27 EAK87692.1 - 1.9e-15 56.0 4.0 0.007 16.2 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 EAK87692.1 - 0.00014 21.5 0.0 0.00014 21.5 0.0 2.7 2 1 1 3 3 3 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EAK87692.1 - 0.00042 20.1 0.4 0.00042 20.1 0.3 2.5 3 1 0 3 3 3 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 EAK87692.1 - 0.04 13.7 0.2 0.18 11.6 0.0 2.1 2 1 0 2 2 2 0 Prp18 domain Phage_CII PF05269.6 EAK87692.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage CII protein Cep57_MT_bd PF06657.8 EAK87693.1 - 0.018 14.9 0.7 2.6 8.0 0.0 3.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SHS2_FTSA PF02491.15 EAK87693.1 - 1.7 8.5 5.3 1.7 8.5 0.7 2.9 2 1 1 3 3 3 0 SHS2 domain inserted in FTSA DUF3879 PF12995.2 EAK87694.1 - 0.012 15.2 0.5 0.014 15.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) zf-RING_2 PF13639.1 EAK87695.1 - 0.066 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Ring finger domain DUF2095 PF09868.4 EAK87697.1 - 0.062 13.0 1.0 0.077 12.7 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) MMS19_N PF14500.1 EAK87698.1 - 4.1e-12 45.9 13.8 4.1e-07 29.5 0.2 4.9 6 0 0 6 6 6 3 Dos2-interacting transcription regulator of RNA-Pol-II HJURP_C PF12347.3 EAK87698.1 - 0.054 13.0 0.3 0.14 11.7 0.2 1.6 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat DUF4477 PF14780.1 EAK87699.1 - 0.0017 17.7 10.3 0.0053 16.1 0.7 3.3 1 1 2 3 3 3 3 Domain of unknown function (DUF4477) Peroxin-13_N PF04088.8 EAK87699.1 - 0.16 11.8 1.4 0.36 10.7 0.6 1.9 1 1 1 2 2 2 0 Peroxin 13, N-terminal region HTH_9 PF08221.6 EAK87700.1 - 2.7e-06 27.1 3.0 0.013 15.3 0.0 4.2 3 1 1 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain SNF2_N PF00176.18 EAK87701.1 - 1e-60 205.1 0.1 6.3e-31 107.2 0.1 2.6 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EAK87701.1 - 4.7e-13 48.8 0.0 8.3e-12 44.8 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EAK87701.1 - 2.8e-07 30.2 1.6 2.8e-07 30.2 1.1 3.3 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 EAK87701.1 - 4.2e-05 23.1 3.1 4.2e-05 23.1 2.1 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EAK87701.1 - 0.00012 22.0 0.9 0.00062 19.8 0.2 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-PARP PF00645.13 EAK87701.1 - 0.00032 20.8 0.0 0.00032 20.8 0.0 4.4 5 0 0 5 5 5 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C3HC4_2 PF13923.1 EAK87701.1 - 0.0015 18.5 3.4 0.0015 18.5 2.4 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2HC_2 PF13913.1 EAK87701.1 - 0.03 13.9 0.4 0.14 11.8 0.3 2.2 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-Apc11 PF12861.2 EAK87701.1 - 0.038 13.8 0.8 0.11 12.4 0.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_5 PF13893.1 EAK87702.1 - 5.7e-05 22.8 0.0 0.00015 21.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK87702.1 - 0.0036 17.2 0.1 0.025 14.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAK87702.1 - 0.0058 16.2 0.0 0.021 14.4 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 PF00013.24 EAK87702.1 - 0.054 13.1 0.1 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 KH domain SUI1 PF01253.17 EAK87703.1 - 1.8e-18 66.0 0.1 1.4e-17 63.2 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor SUI1 PUA PF01472.15 EAK87703.1 - 0.00067 19.3 0.0 0.002 17.8 0.0 1.9 1 1 0 1 1 1 1 PUA domain AAA_12 PF13087.1 EAK87703.1 - 0.22 10.8 10.6 0.046 13.1 0.5 3.2 3 0 0 3 3 3 0 AAA domain Syja_N PF02383.13 EAK87704.1 - 8.8e-80 267.8 3.5 1.4e-79 267.1 2.4 1.3 1 0 0 1 1 1 1 SacI homology domain NanE PF04131.9 EAK87704.1 - 0.17 10.8 0.1 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase RRP7 PF12923.2 EAK87705.1 - 1.5e-20 73.5 7.1 2.6e-20 72.7 4.9 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) Ribosomal_L14e PF01929.12 EAK87705.1 - 0.00035 20.8 5.3 0.00035 20.8 3.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L14 Ndufs5 PF10200.4 EAK87705.1 - 0.061 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF2310 PF10071.4 EAK87705.1 - 0.12 11.3 2.1 0.22 10.4 0.5 1.9 1 1 1 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) ThiF PF00899.16 EAK87707.1 - 1.6e-23 83.0 0.0 2.8e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EAK87707.1 - 0.047 13.7 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4548 PF15081.1 EAK87707.1 - 0.087 12.3 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4548) WD40 PF00400.27 EAK87709.1 - 0.3 11.0 2.9 5 7.1 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat DNA_primase_S PF01896.14 EAK87710.1 - 3.5e-52 176.0 3.0 1e-51 174.5 2.1 1.7 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Albumin_I PF08027.6 EAK87710.1 - 0.11 12.1 0.7 0.32 10.7 0.1 2.0 2 1 0 2 2 2 0 Albumin I V_ATPase_I PF01496.14 EAK87711.1 - 2.2e-162 541.6 25.5 6.1e-131 437.7 15.7 2.0 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family Scaffolding_pro PF11418.3 EAK87711.1 - 0.18 12.1 1.8 0.25 11.6 0.3 1.9 2 0 0 2 2 2 0 Phi29 scaffolding protein DUF663 PF04950.7 EAK87712.1 - 2.9e-75 252.9 1.4 2.9e-75 252.9 1.0 2.8 4 0 0 4 4 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EAK87712.1 - 1.1e-29 101.8 0.0 3.2e-29 100.2 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EAK87712.1 - 6.2e-07 29.0 0.0 1.9e-05 24.1 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EAK87712.1 - 2.1e-05 24.6 0.0 6.2e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EAK87712.1 - 4.1e-05 23.7 0.0 0.00015 21.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EAK87712.1 - 5.4e-05 22.7 0.0 0.00014 21.3 0.0 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EAK87712.1 - 7.6e-05 23.5 4.0 9.9e-05 23.1 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EAK87712.1 - 0.00066 19.5 0.3 0.0022 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAK87712.1 - 0.00081 19.4 0.0 0.0025 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EAK87712.1 - 0.00088 18.9 0.1 0.0032 17.1 0.1 2.0 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EAK87712.1 - 0.0016 17.9 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EAK87712.1 - 0.0025 17.5 0.1 0.0066 16.1 0.1 1.7 1 0 0 1 1 1 1 NTPase AAA_18 PF13238.1 EAK87712.1 - 0.0031 17.8 0.0 0.0031 17.8 0.0 4.7 5 2 1 6 6 4 1 AAA domain AAA_19 PF13245.1 EAK87712.1 - 0.0034 17.0 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EAK87712.1 - 0.0037 16.9 0.0 0.0088 15.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 EAK87712.1 - 0.004 17.0 0.2 0.017 15.0 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EAK87712.1 - 0.0046 16.8 0.0 0.024 14.5 0.0 2.3 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EAK87712.1 - 0.005 16.4 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 EAK87712.1 - 0.0069 15.9 0.0 0.029 13.9 0.0 2.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Miro PF08477.8 EAK87712.1 - 0.0077 16.7 0.0 0.043 14.3 0.0 2.3 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EAK87712.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAK87712.1 - 0.024 14.9 0.0 0.024 14.9 0.0 4.2 4 1 0 4 4 3 0 ABC transporter AAA_30 PF13604.1 EAK87712.1 - 0.07 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAK87713.1 - 1.6e-18 67.3 0.0 2.7e-09 37.4 0.0 3.0 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 EAK87713.1 - 2.2e-06 27.0 1.9 0.00022 20.6 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MobB PF03205.9 EAK87713.1 - 0.0044 16.7 1.0 0.02 14.6 0.1 2.4 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EAK87713.1 - 0.0051 17.1 5.6 0.0051 17.1 3.9 5.0 4 1 0 4 4 4 1 AAA domain AAA_17 PF13207.1 EAK87713.1 - 0.0061 17.3 0.0 0.028 15.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAK87713.1 - 0.0093 16.2 1.3 0.018 15.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.10 EAK87713.1 - 0.029 14.0 0.1 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 NTPase Miro PF08477.8 EAK87713.1 - 0.032 14.7 0.1 6.5 7.2 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein CLP_protease PF00574.18 EAK87713.1 - 0.033 13.8 0.0 0.086 12.4 0.0 1.6 1 0 0 1 1 1 0 Clp protease T2SE PF00437.15 EAK87713.1 - 0.12 11.2 0.5 0.25 10.1 0.3 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EAK87713.1 - 0.13 12.1 0.4 1.4 8.9 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 EAK87713.1 - 0.27 10.5 0.1 0.7 9.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EAK87713.1 - 0.35 10.4 0.1 1 8.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EAK87713.1 - 1.3 8.7 8.7 0.2 11.4 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 Bromodomain PF00439.20 EAK87714.1 - 3.5e-28 97.3 5.7 1.2e-17 63.6 0.2 3.7 2 0 0 2 2 2 2 Bromodomain FAD_binding_1 PF00667.15 EAK87715.1 - 2.3e-32 112.2 2.1 4.3e-30 104.7 0.5 3.1 2 1 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 EAK87715.1 - 2.9e-10 40.3 0.0 1.7e-08 34.5 0.0 2.3 1 1 0 1 1 1 1 Flavodoxin NAD_binding_6 PF08030.7 EAK87715.1 - 0.0001 22.2 0.1 0.0001 22.2 0.1 2.7 3 0 0 3 3 3 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EAK87715.1 - 0.044 14.3 0.0 0.28 11.7 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Rtf2 PF04641.7 EAK87716.1 - 6.7e-13 48.4 0.1 7.8e-13 48.2 0.1 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger Nop14 PF04147.7 EAK87717.1 - 8.4 4.1 5.8 12 3.6 4.0 1.1 1 0 0 1 1 1 0 Nop14-like family tRNA_int_endo PF01974.12 EAK87718.1 - 1.1e-19 69.9 3.6 5.6e-19 67.7 2.5 1.9 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Radical_SAM PF04055.16 EAK87719.1 - 2.2e-05 24.6 0.6 0.00067 19.8 0.0 3.2 2 1 1 3 3 3 1 Radical SAM superfamily Fer4_14 PF13394.1 EAK87719.1 - 0.0052 16.8 0.0 0.019 15.0 0.0 2.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain WD40 PF00400.27 EAK87720.1 - 6.2e-19 67.0 0.1 0.00016 21.4 0.0 5.7 7 0 0 7 7 7 3 WD domain, G-beta repeat zf-met2 PF12907.2 EAK87721.1 - 4.8e-16 58.4 5.8 6.4e-16 58.0 4.0 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EAK87721.1 - 1.4e-11 44.9 1.9 2e-11 44.4 1.3 1.2 1 0 0 1 1 1 1 4F5 protein family zf-BED PF02892.10 EAK87721.1 - 0.065 12.9 0.4 0.1 12.3 0.3 1.4 1 0 0 1 1 1 0 BED zinc finger Elf1 PF05129.8 EAK87721.1 - 0.26 11.0 4.0 0.46 10.2 2.8 1.6 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like ASF1_hist_chap PF04729.8 EAK87722.1 - 1.6e-65 219.4 0.1 2.2e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone NAP PF00956.13 EAK87723.1 - 2e-64 217.0 4.6 3.9e-64 216.0 3.2 1.5 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) DNA_pol_phi PF04931.8 EAK87723.1 - 5.3 4.6 24.5 0.13 10.0 12.5 1.5 2 0 0 2 2 2 0 DNA polymerase phi UQ_con PF00179.21 EAK87724.1 - 6.9e-51 171.3 0.0 8e-51 171.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAK87724.1 - 1.1e-05 25.1 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EAK87724.1 - 0.00099 18.9 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EAK87724.1 - 0.0064 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 UEV domain Saccharop_dh PF03435.13 EAK87725.1 - 4.4e-08 32.5 0.0 5.7e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase UPF0113 PF03657.8 EAK87726.1 - 3.9e-14 52.6 0.1 4.5e-14 52.4 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Gly_acyl_tr_N PF06021.6 EAK87726.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase HBS1_N PF08938.5 EAK87727.1 - 0.011 15.8 3.2 0.27 11.3 0.1 2.4 2 0 0 2 2 2 0 HBS1 N-terminus XPA_C PF05181.7 EAK87727.1 - 0.028 14.0 0.1 0.067 12.7 0.0 1.7 1 1 0 1 1 1 0 XPA protein C-terminus Elf1 PF05129.8 EAK87727.1 - 9.8 5.9 7.8 25 4.6 0.5 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Ribosomal_L18e PF00828.14 EAK87728.1 - 3.2e-23 82.4 0.1 4.8e-23 81.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 UPF0016 PF01169.14 EAK87729.1 - 2.6e-45 152.4 13.8 3.3e-24 84.8 0.8 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 EAK87729.1 - 0.018 14.5 0.3 0.018 14.5 0.2 2.0 2 0 0 2 2 2 0 Integral membrane protein TerC family FTR1 PF03239.9 EAK87729.1 - 2.1 7.1 10.2 0.022 13.6 0.5 2.0 2 0 0 2 2 2 0 Iron permease FTR1 family DUF204 PF02659.10 EAK87729.1 - 8.4 6.6 12.8 6.2 7.0 1.3 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF CDP-OH_P_transf PF01066.16 EAK87730.1 - 3.1e-17 62.7 0.6 3.1e-17 62.7 0.4 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase zf-C2H2_7 PF15269.1 EAK87730.1 - 0.038 13.8 0.7 0.14 12.0 0.5 2.0 1 0 0 1 1 1 0 Zinc-finger B56 PF01603.15 EAK87731.1 - 4.2e-127 424.1 19.6 8.5e-127 423.1 13.6 1.5 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF1947 PF09183.5 EAK87731.1 - 0.043 13.5 2.6 1.1 9.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) Proteasome PF00227.21 EAK87732.1 - 2.7e-57 193.1 0.0 3.7e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAK87732.1 - 1.6e-14 52.8 0.4 2.8e-14 52.0 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature UQ_con PF00179.21 EAK87733.1 - 2.9e-41 140.1 0.0 4.1e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.26 EAK87733.1 - 2.2e-06 27.3 0.1 4.9e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.1 EAK87733.1 - 3.4e-06 26.8 0.0 6.5e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EAK87733.1 - 0.0014 18.5 0.2 0.002 17.9 0.1 1.6 1 1 0 1 1 1 1 RWD domain UBA_3 PF09288.5 EAK87733.1 - 0.0032 17.0 0.5 0.013 15.0 0.3 2.0 1 1 0 1 1 1 1 Fungal ubiquitin-associated domain E3_UbLigase_EDD PF11547.3 EAK87733.1 - 0.0097 15.3 0.1 0.02 14.4 0.1 1.4 1 0 0 1 1 1 1 E3 ubiquitin ligase EDD UBA_4 PF14555.1 EAK87733.1 - 0.017 14.6 0.7 0.043 13.3 0.5 1.6 1 1 0 1 1 1 0 UBA-like domain UEV PF05743.8 EAK87733.1 - 0.036 13.7 0.2 0.066 12.8 0.1 1.5 1 1 0 1 1 1 0 UEV domain Nop PF01798.13 EAK87734.1 - 4.9e-27 94.0 0.0 8.6e-27 93.2 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 EAK87734.1 - 3.8e-26 91.9 3.0 8.3e-26 90.8 2.1 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 EAK87734.1 - 1.2e-07 31.4 3.3 1.5e-07 31.0 0.3 2.3 2 0 0 2 2 2 1 NOSIC (NUC001) domain CAF1C_H4-bd PF12265.3 EAK87735.1 - 1.4e-08 34.4 0.1 6.1e-08 32.4 0.1 2.1 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 EAK87735.1 - 0.00016 21.4 18.4 0.025 14.4 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat GCC2_GCC3 PF07699.8 EAK87736.1 - 4.7e-05 22.8 31.6 0.0051 16.3 5.0 4.4 2 2 2 4 4 4 3 GCC2 and GCC3 hEGF PF12661.2 EAK87736.1 - 0.05 13.6 8.5 0.73 10.0 0.6 3.2 3 0 0 3 3 3 0 Human growth factor-like EGF PMM PF03332.8 EAK87737.1 - 4.5e-99 330.4 2.4 5.6e-99 330.1 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EAK87737.1 - 5.7e-10 39.2 0.1 2.3e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EAK87737.1 - 5.3e-05 22.6 0.0 0.075 12.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EAK87737.1 - 0.018 15.2 3.2 0.61 10.2 0.0 2.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAK87737.1 - 0.097 13.0 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RPA_C PF08784.6 EAK87739.1 - 0.02 15.2 0.8 0.041 14.2 0.5 1.6 1 1 0 1 1 1 0 Replication protein A C terminal DUF4500 PF14937.1 EAK87739.1 - 0.077 12.8 0.1 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) tRNA_bind PF01588.15 EAK87740.1 - 2.2e-26 91.5 0.0 4.3e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.20 EAK87740.1 - 0.0003 20.7 0.0 0.00071 19.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAK87740.1 - 0.0011 19.4 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain V-SNARE_C PF12352.3 EAK87742.1 - 4.9e-08 32.9 1.6 1.2e-07 31.6 1.1 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Lipase_GDSL_3 PF14606.1 EAK87742.1 - 0.05 13.3 2.8 0.041 13.6 0.6 1.7 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DHO_dh PF01180.16 EAK87742.1 - 0.079 11.8 1.5 0.12 11.3 1.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase H-kinase_dim PF02895.9 EAK87742.1 - 0.96 9.8 7.5 20 5.5 0.4 3.2 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Sec20 PF03908.8 EAK87742.1 - 4.2 7.1 16.5 0.12 12.1 3.1 2.9 2 1 2 4 4 4 0 Sec20 eIF-3c_N PF05470.7 EAK87744.1 - 1.5e-115 386.6 40.3 9.5e-67 225.4 1.8 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EAK87744.1 - 1.3e-09 38.3 0.4 1.3e-09 38.3 0.3 2.7 3 0 0 3 3 3 1 PCI domain Phage_Integr_2 PF13009.1 EAK87745.1 - 0.012 14.6 1.7 0.013 14.4 1.2 1.1 1 0 0 1 1 1 0 Putative phage integrase Baculo_PEP_C PF04513.7 EAK87745.1 - 0.097 12.4 0.7 0.25 11.1 0.5 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DnaB PF00772.16 EAK87745.1 - 0.12 12.3 0.8 0.16 11.8 0.6 1.2 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain AbiH PF14253.1 EAK87745.1 - 0.14 11.7 9.4 0.15 11.6 6.5 1.0 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF342 PF03961.8 EAK87745.1 - 1.2 7.5 5.9 1.3 7.3 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DnaI_N PF07319.6 EAK87745.1 - 4.3 7.6 8.2 6.7 7.0 3.8 2.1 1 1 1 2 2 2 0 Primosomal protein DnaI N-terminus Ank_2 PF12796.2 EAK87746.1 - 2.2e-19 69.5 0.6 4e-09 36.6 0.1 4.2 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAK87746.1 - 1.7e-13 50.6 5.2 3.6e-06 27.3 0.1 6.1 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.25 EAK87746.1 - 1.1e-08 34.3 2.2 0.0008 19.1 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EAK87746.1 - 1.8e-05 24.8 0.7 0.04 14.1 0.1 4.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAK87746.1 - 2.8e-05 23.9 9.5 0.035 14.3 0.1 6.5 8 0 0 8 8 8 2 Ankyrin repeat Ank_2 PF12796.2 EAK87747.1 - 5.7e-25 87.4 0.0 1e-15 57.7 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAK87747.1 - 6.3e-22 76.2 0.1 7.5e-06 25.5 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 EAK87747.1 - 3.7e-18 63.8 2.0 4.8e-05 23.2 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EAK87747.1 - 3.7e-18 65.5 1.1 2.1e-07 31.2 0.0 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAK87747.1 - 1.8e-17 62.9 0.1 8.3e-11 41.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) AP2 PF00847.15 EAK87748.1 - 1.2e-07 31.8 1.1 4e-07 30.0 0.7 2.0 1 0 0 1 1 1 1 AP2 domain TFIIE_alpha PF02002.12 EAK87749.1 - 0.0011 18.4 0.1 0.0051 16.2 0.0 2.1 2 0 0 2 2 2 1 TFIIE alpha subunit HTH_Mga PF08280.6 EAK87749.1 - 0.0039 16.9 0.8 0.039 13.7 0.1 2.6 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_24 PF13412.1 EAK87749.1 - 0.0041 16.4 0.1 0.013 14.8 0.1 1.9 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding GntR PF00392.16 EAK87749.1 - 0.0078 15.6 1.4 0.0095 15.3 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.7 EAK87749.1 - 0.015 14.9 0.1 0.037 13.6 0.1 1.6 1 0 0 1 1 1 0 HTH domain TrmB PF01978.14 EAK87749.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Methyltransf_8 PF05148.10 EAK87750.1 - 5e-53 179.9 1.5 2.2e-52 177.8 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EAK87750.1 - 1.5e-06 28.6 0.0 2.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAK87750.1 - 8.9e-05 22.1 2.2 0.00028 20.5 1.5 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAK87750.1 - 0.0098 15.6 0.0 0.032 13.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain HWE_HK PF07536.9 EAK87752.1 - 0.013 15.8 0.3 7.6 7.0 0.0 2.9 2 0 0 2 2 2 0 HWE histidine kinase Pkinase PF00069.20 EAK87754.1 - 1.5e-36 125.8 0.5 1.9e-30 105.8 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAK87754.1 - 1.4e-10 40.7 0.0 1.6e-05 24.1 0.0 3.4 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAK87754.1 - 0.0004 19.4 0.1 1.9 7.3 0.0 3.3 4 0 0 4 4 4 2 Kinase-like Kdo PF06293.9 EAK87754.1 - 0.18 10.8 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BCNT PF07572.7 EAK87755.1 - 4.7e-20 71.3 2.7 7.5e-20 70.6 1.9 1.4 1 0 0 1 1 1 1 Bucentaur or craniofacial development DUF1053 PF06327.9 EAK87755.1 - 0.039 14.2 0.2 0.056 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) Methyltransf_26 PF13659.1 EAK87756.1 - 5.4e-11 42.5 0.0 1.2e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAK87756.1 - 1.3e-08 34.3 0.0 1.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EAK87756.1 - 1.5e-08 34.3 0.0 2.6e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EAK87756.1 - 0.00015 21.3 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EAK87756.1 - 0.00062 19.4 0.0 0.00097 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAK87756.1 - 0.0022 18.5 0.0 0.0032 18.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAK87756.1 - 0.0052 17.1 0.0 0.0092 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain rRNA_methylase PF06962.7 EAK87756.1 - 0.0067 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative rRNA methylase Methyltransf_28 PF02636.12 EAK87756.1 - 0.057 12.8 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase N6_Mtase PF02384.11 EAK87756.1 - 0.063 12.3 0.0 0.21 10.6 0.0 1.7 2 0 0 2 2 2 0 N-6 DNA Methylase UPF0020 PF01170.13 EAK87756.1 - 0.08 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TRM13 PF05206.9 EAK87756.1 - 0.085 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 Methyltransf_24 PF13578.1 EAK87756.1 - 0.096 13.5 0.0 0.2 12.4 0.0 1.5 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_10 PF05971.7 EAK87756.1 - 0.12 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF890) Methyltransf_4 PF02390.12 EAK87756.1 - 0.13 11.2 0.0 0.37 9.7 0.0 1.8 2 1 0 2 2 2 0 Putative methyltransferase PRTP PF01366.13 EAK87757.1 - 0.029 12.3 0.2 0.033 12.1 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein RNA_pol_Rpo13 PF12136.3 EAK87758.1 - 0.035 13.7 11.9 0.067 12.8 8.2 1.5 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain eIF3g PF12353.3 EAK87758.1 - 0.087 12.7 1.2 0.14 12.0 0.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Phosducin PF02114.11 EAK87758.1 - 0.098 11.3 5.6 0.13 10.9 3.9 1.1 1 0 0 1 1 1 0 Phosducin DUF1980 PF09323.5 EAK87758.1 - 0.14 11.8 0.7 0.21 11.3 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DRY_EERY PF09750.4 EAK87758.1 - 0.36 10.9 3.7 0.71 9.9 2.5 1.5 2 0 0 2 2 2 0 Alternative splicing regulator CDV3 PF15359.1 EAK87758.1 - 0.38 10.8 4.2 0.54 10.3 2.9 1.3 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Nucleoplasmin PF03066.10 EAK87758.1 - 0.62 9.5 6.4 0.91 9.0 4.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin Collagen PF01391.13 EAK87759.1 - 0.0048 16.4 38.0 2.4e+02 1.3 22.9 3.2 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) Lge1 PF11488.3 EAK87759.1 - 0.68 10.1 5.3 3.6 7.8 0.2 3.3 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 V-ATPase_H_C PF11698.3 EAK87760.1 - 0.0069 16.3 0.7 0.069 13.0 0.0 2.7 3 0 0 3 3 3 1 V-ATPase subunit H V-SNARE_C PF12352.3 EAK87760.1 - 0.037 14.0 0.8 0.15 12.1 0.5 2.1 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus CAP_N PF01213.14 EAK87760.1 - 0.058 12.6 0.2 0.14 11.4 0.0 1.7 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Lge1 PF11488.3 EAK87760.1 - 0.17 12.0 1.9 8.5 6.6 0.5 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Allexi_40kDa PF05549.6 EAK87762.1 - 0.029 13.6 6.1 0.035 13.3 4.1 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein ParcG PF10274.4 EAK87762.1 - 0.034 14.0 0.7 3.6 7.4 0.1 2.3 1 1 0 2 2 2 0 Parkin co-regulated protein SIR2 PF02146.12 EAK87762.1 - 0.064 12.9 2.6 0.093 12.4 0.6 1.8 1 1 0 2 2 2 0 Sir2 family DUF2076 PF09849.4 EAK87762.1 - 0.075 13.0 0.4 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DASH_Dad4 PF08650.5 EAK87762.1 - 0.64 9.9 4.3 4.4 7.2 0.2 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad4 IncA PF04156.9 EAK87763.1 - 0.00016 21.3 0.6 0.00016 21.3 0.4 2.7 2 1 1 3 3 3 1 IncA protein DUF2935 PF11155.3 EAK87763.1 - 0.48 10.5 2.0 0.29 11.2 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Caps_assemb_Wzi PF14052.1 EAK87765.1 - 0.00033 19.6 1.9 0.0006 18.7 1.3 1.5 1 1 0 1 1 1 1 Capsule assembly protein Wzi Viral_Beta_CD PF04530.7 EAK87767.1 - 0.00052 20.1 2.0 0.78 9.9 0.1 2.8 2 0 0 2 2 2 2 Viral Beta C/D like family Kazal_2 PF07648.10 EAK87770.1 - 2.9e-80 263.9 106.7 3.6e-11 42.8 3.4 12.9 13 0 0 13 13 13 12 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EAK87770.1 - 5.5e-75 247.2 126.3 1.7e-10 40.7 3.4 13.2 13 0 0 13 13 13 12 Kazal-type serine protease inhibitor domain SSP160 PF06933.6 EAK87770.1 - 0.12 10.2 12.5 0.36 8.7 8.7 1.7 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CCDC-167 PF15188.1 EAK87775.1 - 0.00057 19.7 20.7 0.01 15.7 0.6 5.1 5 0 0 5 5 5 3 Coiled-coil domain-containing protein 167 DUF1465 PF07323.7 EAK87775.1 - 0.008 15.7 0.3 0.035 13.6 0.2 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1465) SM-ATX PF14438.1 EAK87777.1 - 0.016 15.0 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF1108 PF06531.6 EAK87779.1 - 0.0046 17.0 1.4 0.021 14.9 1.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1108) ASFV_J13L PF05568.6 EAK87779.1 - 0.079 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF2500 PF10694.4 EAK87779.1 - 1.2 9.1 6.4 2.1 8.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) Helicase_Sgs1 PF11408.3 EAK87782.1 - 0.22 11.3 10.6 0.087 12.6 0.4 3.8 3 0 0 3 3 3 0 Sgs1 RecQ helicase Vps53_N PF04100.7 EAK87783.1 - 1.2e-18 67.0 28.8 4.5e-16 58.5 19.9 3.7 1 1 0 1 1 1 1 Vps53-like, N-terminal DUF3863 PF12979.2 EAK87783.1 - 0.0039 15.8 0.0 0.0084 14.7 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3863) DUF1025 PF06262.6 EAK87783.1 - 0.1 12.4 0.0 0.38 10.5 0.0 1.9 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Serglycin PF04360.7 EAK87784.1 - 0.0036 17.0 2.7 0.0056 16.4 0.5 2.3 2 0 0 2 2 2 1 Serglycin AMP-binding PF00501.23 EAK87785.1 - 1.6e-71 240.8 0.0 2.3e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ETRAMP PF09716.5 EAK87785.1 - 0.0098 15.8 0.0 0.035 14.0 0.0 2.0 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF643 PF04867.7 EAK87785.1 - 0.018 15.4 0.1 0.064 13.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF643) RSS_P20 PF11757.3 EAK87785.1 - 0.11 12.5 0.0 0.37 10.9 0.0 1.9 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like Beach PF02138.13 EAK87786.1 - 3.3e-69 233.3 10.9 1.4e-68 231.2 4.5 3.2 2 1 0 2 2 2 1 Beige/BEACH domain GATA PF00320.22 EAK87789.1 - 0.031 13.6 6.1 0.066 12.5 0.3 2.4 2 0 0 2 2 2 0 GATA zinc finger Prok-E2_C PF14459.1 EAK87789.1 - 0.92 9.5 4.2 0.95 9.5 0.1 2.5 2 0 0 2 2 2 0 Prokaryotic E2 family C PH PF00169.24 EAK87790.1 - 9.8e-07 28.9 1.6 2.4e-05 24.4 0.0 3.5 3 2 0 3 3 3 1 PH domain PH_11 PF15413.1 EAK87790.1 - 4.8e-05 23.5 1.3 0.0012 19.1 0.3 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 EAK87790.1 - 0.0022 18.0 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EAK87790.1 - 0.0037 17.2 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain NOC3p PF07540.6 EAK87791.1 - 1.5e-12 47.6 0.1 1.5e-12 47.6 0.1 2.8 3 1 0 3 3 3 1 Nucleolar complex-associated protein DUF2668 PF10873.3 EAK87791.1 - 0.054 13.6 0.1 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) PGM_PMM_I PF02878.11 EAK87792.1 - 4.3e-15 55.4 0.0 9.5e-08 31.6 0.0 2.8 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EAK87792.1 - 5.7e-09 36.2 0.0 2.1e-07 31.1 0.0 2.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EAK87792.1 - 1.1e-06 28.5 0.0 4.5e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain IMCp PF12314.3 EAK87793.1 - 1.3e-09 38.0 48.3 6e-08 32.7 21.2 3.3 1 1 2 3 3 3 2 Inner membrane complex protein IMCp PF12314.3 EAK87794.1 - 2.5e-13 49.9 33.7 2.5e-13 49.9 23.3 2.9 2 0 0 2 2 2 1 Inner membrane complex protein NIF PF03031.13 EAK87795.1 - 1.2e-41 141.9 2.6 3.7e-41 140.4 0.4 2.2 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase TRM PF02005.11 EAK87796.1 - 5.2e-93 311.9 6.4 9.6e-66 222.2 2.5 3.5 2 1 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.8 EAK87796.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EAK87796.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EAK87797.1 - 0.0044 16.1 1.1 1.3 8.1 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain DrrA_P4M PF14860.1 EAK87798.1 - 0.024 14.3 1.2 0.049 13.3 0.8 1.6 1 1 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Ribosomal_S3Ae PF01015.13 EAK87799.1 - 1.1e-79 266.2 1.8 1.4e-79 266.0 1.2 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EAK87799.1 - 0.01 15.1 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Oxidored_molyb PF00174.14 EAK87799.1 - 0.095 12.1 0.1 1.1 8.6 0.1 2.2 1 1 0 1 1 1 0 Oxidoreductase molybdopterin binding domain Cullin PF00888.17 EAK87800.1 - 8.6e-100 334.9 31.2 1.2e-99 334.5 21.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EAK87800.1 - 6.6e-19 67.5 1.5 2.5e-18 65.6 1.0 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain TPT PF03151.11 EAK87801.1 - 5.5e-23 81.3 28.3 1.5e-21 76.6 8.1 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 EAK87801.1 - 2.5e-09 36.5 18.1 2.5e-09 36.5 12.5 1.7 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 EAK87801.1 - 0.00026 21.0 26.1 0.00087 19.3 1.3 3.2 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EAK87801.1 - 0.0064 15.3 8.7 0.0087 14.9 0.5 2.5 3 0 0 3 3 3 2 Eukaryotic protein of unknown function (DUF914) UPF0546 PF10639.4 EAK87801.1 - 0.008 15.9 1.3 0.008 15.9 0.9 2.2 2 0 0 2 2 2 1 Uncharacterised protein family UPF0546 EmrE PF13536.1 EAK87801.1 - 0.027 14.6 1.5 0.027 14.6 1.0 3.3 3 0 0 3 3 3 0 Multidrug resistance efflux transporter eIF-6 PF01912.13 EAK87802.1 - 2.7e-80 268.1 1.4 2.7e-80 268.1 0.9 1.4 2 0 0 2 2 2 1 eIF-6 family Guanylate_cyc PF00211.15 EAK87803.1 - 3.1e-17 62.5 0.0 6e-08 32.2 0.0 3.4 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain EB PF01683.13 EAK87804.1 - 0.0011 18.9 35.6 0.34 10.9 0.4 9.9 5 4 2 7 7 7 3 EB module Prok-E2_C PF14459.1 EAK87804.1 - 0.89 9.6 3.1 1.8 8.6 0.0 3.0 3 2 1 4 4 4 0 Prokaryotic E2 family C CPW_WPC PF09717.5 EAK87804.1 - 1.3 9.7 39.0 33 5.1 0.0 11.0 6 5 5 11 11 11 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Baculo_VP91_N PF08475.5 EAK87804.1 - 3.1 7.1 8.0 23 4.2 0.1 4.5 4 1 1 5 5 5 0 Viral capsid protein 91 N-terminal cEGF PF12662.2 EAK87804.1 - 7.1 6.3 78.5 1.4 8.6 0.4 15.1 16 2 0 16 16 16 0 Complement Clr-like EGF-like Calcyon PF06387.6 EAK87804.1 - 8.3 5.7 21.7 1.8 7.9 0.3 7.2 6 2 2 8 8 8 0 D1 dopamine receptor-interacting protein (calcyon) TMEM51 PF15345.1 EAK87805.1 - 0.0011 18.7 5.7 0.0013 18.4 4.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 PROL5-SMR PF15621.1 EAK87805.1 - 0.0032 17.8 0.0 0.0056 17.1 0.0 1.5 1 1 0 1 1 1 1 Proline-rich submaxillary gland androgen-regulated family DUF4407 PF14362.1 EAK87805.1 - 0.019 13.9 0.7 0.025 13.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM176 PF14851.1 EAK87805.1 - 0.02 14.5 3.3 0.021 14.5 0.3 1.9 1 1 1 2 2 2 0 FAM176 family RIC3 PF15361.1 EAK87805.1 - 0.031 14.5 0.2 0.031 14.5 0.1 2.2 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Polysacc_synt PF01943.12 EAK87805.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Mem_trans PF03547.13 EAK87805.1 - 0.14 10.3 2.4 0.17 10.1 1.7 1.1 1 0 0 1 1 1 0 Membrane transport protein Hid1 PF12722.2 EAK87805.1 - 0.24 9.0 7.3 0.26 8.9 5.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 EAK87805.1 - 0.46 10.3 4.6 0.53 10.1 3.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Shisa PF13908.1 EAK87805.1 - 0.72 10.0 7.6 4.2 7.4 5.3 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator OAD_gamma PF04277.8 EAK87805.1 - 0.76 10.1 8.0 65 3.9 5.6 2.6 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF2215 PF10225.4 EAK87805.1 - 0.85 9.0 3.1 1.1 8.6 2.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Allexi_40kDa PF05549.6 EAK87805.1 - 1.6 7.9 6.5 1.9 7.7 4.5 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein NPR3 PF03666.8 EAK87805.1 - 2 6.8 11.9 2.6 6.4 8.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.12 EAK87805.1 - 4.2 6.0 7.4 5.1 5.8 5.1 1.2 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.6 EAK87805.1 - 5.1 5.2 15.6 5.8 5.0 10.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Abhydrolase_2 PF02230.11 EAK87807.1 - 3.6e-06 26.5 0.1 7.6e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EAK87807.1 - 5.1e-05 23.0 0.0 0.00015 21.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EAK87807.1 - 0.05 13.0 0.0 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EAK87807.1 - 0.081 12.7 0.0 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Aminotran_5 PF00266.14 EAK87808.1 - 1.4e-82 277.3 0.0 1.7e-82 277.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EAK87808.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EAK87808.1 - 0.052 12.5 0.0 0.098 11.6 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Abhydrolase_2 PF02230.11 EAK87809.1 - 1.8e-07 30.8 0.0 2.8e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EAK87809.1 - 3.3e-05 23.6 0.0 5.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EAK87809.1 - 0.029 14.0 0.0 0.069 12.8 0.0 1.6 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Glyco_hydro_42C PF08533.5 EAK87810.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain Tropomyosin PF00261.15 EAK87811.1 - 0.0057 15.7 10.7 0.0093 15.0 5.9 2.1 1 1 1 2 2 2 1 Tropomyosin UXS1_N PF11803.3 EAK87811.1 - 0.0073 16.0 2.4 0.24 11.1 0.0 2.9 3 0 0 3 3 3 1 UDP-glucuronate decarboxylase N-terminal Fib_alpha PF08702.5 EAK87811.1 - 0.0092 16.1 5.6 0.0092 16.1 3.9 3.1 1 1 3 4 4 4 1 Fibrinogen alpha/beta chain family Atg14 PF10186.4 EAK87811.1 - 0.011 14.7 7.0 0.015 14.2 4.5 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 EAK87811.1 - 0.082 13.2 3.8 1.6 9.1 0.1 3.1 3 1 1 4 4 4 0 SlyX NAAA-beta PF15508.1 EAK87811.1 - 0.48 10.8 2.7 24 5.3 0.1 3.3 2 1 2 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase IncA PF04156.9 EAK87811.1 - 0.66 9.5 11.6 0.59 9.7 4.2 2.3 1 1 1 2 2 2 0 IncA protein ING PF12998.2 EAK87811.1 - 0.67 10.2 11.3 0.06 13.6 2.8 2.7 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF1319 PF07028.6 EAK87811.1 - 0.72 10.0 9.3 6.2 7.0 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1319) Prefoldin PF02996.12 EAK87811.1 - 0.73 9.5 11.4 9.1 5.9 0.4 4.6 3 1 2 5 5 5 0 Prefoldin subunit Striatin PF08232.7 EAK87811.1 - 0.75 10.1 11.2 1.2 9.4 4.2 2.5 1 1 1 2 2 2 0 Striatin family ArdA PF07275.6 EAK87811.1 - 0.9 9.7 5.4 2.6 8.2 1.3 2.5 1 1 2 3 3 3 0 Antirestriction protein (ArdA) NPV_P10 PF05531.7 EAK87811.1 - 1 9.6 6.9 46 4.3 2.5 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fzo_mitofusin PF04799.8 EAK87811.1 - 1.2 8.5 11.8 0.55 9.5 0.4 3.4 2 1 1 3 3 3 0 fzo-like conserved region YlqD PF11068.3 EAK87811.1 - 2.2 8.3 8.4 0.75 9.8 0.5 2.9 2 1 1 3 3 3 0 YlqD protein Laminin_II PF06009.7 EAK87811.1 - 2.2 8.0 12.0 0.52 10.0 2.4 2.8 2 1 1 3 3 3 0 Laminin Domain II Reo_sigmaC PF04582.7 EAK87811.1 - 2.3 7.2 6.4 1.7 7.7 1.2 2.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein FlgN PF05130.7 EAK87811.1 - 2.5 8.3 7.2 0.6 10.3 1.0 2.6 2 1 1 3 3 3 0 FlgN protein Med9 PF07544.8 EAK87811.1 - 2.5 7.8 9.6 31 4.4 2.4 3.7 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4200 PF13863.1 EAK87811.1 - 3.5 7.5 14.7 2.5 8.0 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DEAD PF00270.24 EAK87812.1 - 1.1e-46 158.3 0.0 4.6e-46 156.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK87812.1 - 9.4e-29 99.1 0.1 2.4e-28 97.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAK87812.1 - 0.017 14.9 0.0 0.055 13.2 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2454 PF10521.4 EAK87812.1 - 0.15 11.0 0.0 0.3 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) IL6 PF00489.12 EAK87813.1 - 0.043 13.3 1.9 0.61 9.6 0.0 3.0 3 0 0 3 3 3 0 Interleukin-6/G-CSF/MGF family AP2 PF00847.15 EAK87814.1 - 5.4e-07 29.6 5.2 1.7e-06 28.1 0.3 2.7 1 1 1 2 2 2 1 AP2 domain Ribosomal_S30 PF04758.9 EAK87814.1 - 0.03 14.0 0.9 0.07 12.8 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S30 Fis1_TPR_C PF14853.1 EAK87815.1 - 6.2e-10 38.7 4.2 4.2e-05 23.3 0.7 2.5 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 EAK87815.1 - 2.8e-08 33.0 5.2 0.00014 21.5 0.4 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAK87815.1 - 5.1e-08 32.2 10.8 0.0005 19.5 1.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAK87815.1 - 2.6e-07 30.1 3.9 3.2e-07 29.8 1.7 1.8 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 EAK87815.1 - 1.4e-05 25.5 0.2 0.071 13.8 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAK87815.1 - 0.00016 21.5 1.7 0.0003 20.6 1.0 1.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAK87815.1 - 0.00017 21.8 0.3 0.00044 20.5 0.2 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAK87815.1 - 0.0007 19.2 1.4 0.0007 19.2 1.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EAK87815.1 - 0.0041 17.2 6.2 0.0061 16.6 3.8 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.2 EAK87815.1 - 0.0043 16.8 0.6 0.84 9.4 0.1 2.1 1 1 1 2 2 2 2 Domain of Unknown Function (DUF3856) DUF3973 PF13119.1 EAK87815.1 - 0.025 14.4 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) TPR_14 PF13428.1 EAK87815.1 - 0.036 14.6 0.0 2.2 9.1 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Vps52 PF04129.7 EAK87816.1 - 1.5e-08 33.6 21.2 0.00025 19.7 2.5 2.4 2 0 0 2 2 2 2 Vps52 / Sac2 family DivIC PF04977.10 EAK87817.1 - 0.011 15.1 0.1 0.011 15.1 0.1 5.5 5 2 1 6 6 6 0 Septum formation initiator Stork_head PF10264.4 EAK87818.1 - 0.0059 16.7 0.8 0.042 14.0 0.2 2.7 1 1 1 2 2 2 1 Winged helix Storkhead-box1 domain POP1 PF06978.6 EAK87818.1 - 1.5 8.4 5.5 0.26 10.9 0.4 2.3 1 1 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 ketoacyl-synt PF00109.21 EAK87820.1 - 0 1497.2 0.0 1.3e-70 237.7 0.0 7.2 7 0 0 7 7 7 7 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EAK87820.1 - 3.5e-252 820.5 5.6 5.3e-41 139.1 0.0 7.5 7 0 0 7 7 7 7 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EAK87820.1 - 2.5e-181 597.5 0.0 1e-44 152.3 0.0 6.4 6 0 0 6 6 6 4 KR domain adh_short PF00106.20 EAK87820.1 - 3.5e-139 459.7 0.0 7.5e-34 117.0 0.0 6.5 8 0 0 8 8 8 4 short chain dehydrogenase PP-binding PF00550.20 EAK87820.1 - 1.6e-95 313.3 21.3 5.7e-14 52.1 0.1 8.9 8 0 0 8 8 8 8 Phosphopantetheine attachment site Acyl_transf_1 PF00698.16 EAK87820.1 - 7.6e-84 281.7 0.0 4.7e-48 164.1 0.0 2.7 3 0 0 3 3 3 2 Acyl transferase domain NAD_binding_4 PF07993.7 EAK87820.1 - 1.2e-67 227.4 0.0 9.2e-65 218.0 0.0 3.2 4 0 0 4 4 4 2 Male sterility protein PS-DH PF14765.1 EAK87820.1 - 1.5e-66 224.5 0.0 2.1e-26 92.7 0.0 5.0 4 1 0 4 4 4 4 Polyketide synthase dehydratase AMP-binding PF00501.23 EAK87820.1 - 5.9e-60 202.8 0.0 6.6e-59 199.3 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme ADH_zinc_N PF00107.21 EAK87820.1 - 1.9e-42 143.8 0.0 3.7e-15 55.6 0.0 3.9 3 0 0 3 3 3 3 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EAK87820.1 - 4.9e-24 84.7 13.4 0.002 17.1 0.1 7.4 7 0 0 7 7 7 7 Thiolase, N-terminal domain ADH_N PF08240.7 EAK87820.1 - 3.2e-21 75.1 5.8 5.8e-07 29.2 0.0 5.1 4 0 0 4 4 4 3 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EAK87820.1 - 3.7e-13 50.4 0.0 1.6e-06 29.0 0.0 3.6 3 0 0 3 3 3 2 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EAK87820.1 - 7.8e-05 22.2 0.1 0.27 10.7 0.0 3.0 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 EAK87820.1 - 0.0042 17.1 0.0 0.18 11.7 0.0 3.7 5 0 0 5 5 5 1 NADH(P)-binding Sugar_tr PF00083.19 EAK87821.1 - 1e-21 77.0 45.0 4.1e-14 52.0 10.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EAK87821.1 - 9e-08 31.2 46.1 6.1e-05 21.8 8.5 3.5 2 2 1 3 3 3 2 Major Facilitator Superfamily GIDA PF01134.17 EAK87823.1 - 0.14 10.9 8.7 0.17 10.6 6.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Cellulose_synt PF03552.9 EAK87823.1 - 1.2 7.3 7.2 1.9 6.7 5.0 1.3 1 0 0 1 1 1 0 Cellulose synthase zf-LITAF-like PF10601.4 EAK87824.1 - 1.4e-18 66.4 2.6 1.4e-18 66.4 1.8 2.3 1 1 1 2 2 2 1 LITAF-like zinc ribbon domain zf-Di19 PF05605.7 EAK87824.1 - 0.26 11.4 1.7 2.8 8.1 0.2 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.8 EAK87824.1 - 0.64 9.7 5.5 7.9 6.2 1.2 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like HypA PF01155.14 EAK87824.1 - 1.1 9.0 4.2 7.5 6.2 2.9 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 EAK87824.1 - 2.7 7.8 5.2 2.9 7.7 0.9 2.3 2 0 0 2 2 2 0 zinc-ribbons Rubredoxin PF00301.15 EAK87824.1 - 3.6 7.5 6.9 0.35 10.7 0.2 2.5 3 0 0 3 3 3 0 Rubredoxin CDP-OH_P_transf PF01066.16 EAK87826.1 - 6.8e-18 64.8 6.2 6.8e-18 64.8 4.3 2.7 3 1 1 4 4 4 1 CDP-alcohol phosphatidyltransferase Aa_trans PF01490.13 EAK87827.1 - 9.1e-30 103.4 31.1 1.1e-29 103.1 21.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MOZART1 PF12554.3 EAK87828.1 - 1.2e-18 66.2 2.6 1.7e-18 65.8 1.8 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated WD40 PF00400.27 EAK87830.1 - 3.9e-16 58.2 12.9 1.6e-07 30.9 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EAK87830.1 - 0.055 11.6 1.0 0.32 9.0 0.0 2.4 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Brix PF04427.13 EAK87831.1 - 3.6e-47 160.5 0.5 4.6e-47 160.1 0.3 1.1 1 0 0 1 1 1 1 Brix domain E1-E2_ATPase PF00122.15 EAK87832.1 - 7.2e-63 211.6 0.2 1.4e-62 210.7 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EAK87832.1 - 6.7e-34 116.9 1.6 6.7e-34 116.9 1.1 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EAK87832.1 - 5.2e-30 105.4 0.0 2.7e-24 86.7 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EAK87832.1 - 3.2e-16 58.5 0.0 7.6e-16 57.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EAK87832.1 - 1.3e-13 51.5 0.1 1e-12 48.6 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAK87832.1 - 4.1e-08 33.0 5.6 4e-06 26.6 2.5 3.3 2 1 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAK87832.1 - 0.0013 18.3 1.0 0.0013 18.3 0.7 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cdc6_C PF09079.6 EAK87833.1 - 0.067 12.9 3.5 2.1 8.0 0.0 4.0 4 0 0 4 4 4 0 CDC6, C terminal Flavodoxin_1 PF00258.20 EAK87834.1 - 6e-18 65.2 0.0 9.2e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EAK87834.1 - 1.5e-11 44.8 0.0 3.1e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.15 EAK87834.1 - 3.7e-10 39.6 0.2 9.9e-10 38.2 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_NdrI PF07972.6 EAK87834.1 - 0.028 14.3 0.5 0.098 12.5 0.2 2.1 2 0 0 2 2 2 0 NrdI Flavodoxin like Flavodoxin_3 PF12641.2 EAK87834.1 - 0.03 13.7 0.3 0.25 10.7 0.0 2.5 2 1 0 2 2 2 0 Flavodoxin domain Sec7 PF01369.15 EAK87835.1 - 6.8e-63 211.7 10.7 6.8e-63 211.7 7.4 2.1 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 EAK87835.1 - 4.6e-22 78.2 2.2 4.6e-22 78.2 1.5 5.0 6 0 0 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal PI3_PI4_kinase PF00454.22 EAK87836.1 - 6.7e-38 130.4 0.0 1.8e-37 129.0 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EAK87836.1 - 1.2e-12 47.0 0.1 3.8e-12 45.4 0.0 2.0 1 0 0 1 1 1 1 FATC domain PDCD2_C PF04194.8 EAK87837.1 - 3.1e-28 98.4 1.2 6e-28 97.4 0.9 1.4 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Zn-ribbon_8 PF09723.5 EAK87837.1 - 0.61 10.0 4.8 18 5.3 0.1 3.5 3 0 0 3 3 3 0 Zinc ribbon domain OapA PF04225.7 EAK87838.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Opacity-associated protein A LysM-like domain RNA_pol_Rpb2_4 PF04566.8 EAK87838.1 - 7.1 6.5 6.2 11 5.8 0.7 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 4 Oxysterol_BP PF01237.13 EAK87842.1 - 3.1e-129 430.5 3.5 5.2e-129 429.7 2.4 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 EAK87842.1 - 2.6e-06 27.5 0.4 9.9e-06 25.7 0.3 2.1 1 0 0 1 1 1 1 PH domain WD40 PF00400.27 EAK87843.1 - 4.1e-09 35.9 9.8 0.036 13.9 0.4 4.9 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.1 EAK87843.1 - 0.036 14.3 0.4 13 6.1 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain PI-PLC-X PF00388.14 EAK87844.1 - 3.6e-58 195.0 0.0 7e-58 194.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EAK87844.1 - 3.2e-30 104.5 0.0 7.3e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EAK87844.1 - 5.6e-13 48.7 0.1 6.3e-12 45.3 0.0 2.5 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EAK87844.1 - 4.3e-11 42.5 0.0 1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.27 EAK87844.1 - 1.6e-10 39.4 0.0 0.00022 20.2 0.0 3.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EAK87844.1 - 1.2e-08 34.9 6.3 1.1e-06 28.6 0.3 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EAK87844.1 - 5.3e-08 32.0 1.8 0.0011 18.6 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EAK87844.1 - 2.7e-07 30.1 0.1 2e-06 27.2 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair Mcp5_PH PF12814.2 EAK87844.1 - 2e-06 27.7 0.0 4.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_5 PF13202.1 EAK87844.1 - 0.00026 20.1 0.3 0.28 10.6 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.1 EAK87844.1 - 0.00076 19.0 0.1 0.002 17.7 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.2 EAK87844.1 - 0.0012 18.5 1.5 0.34 10.6 0.0 3.3 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand GDPD PF03009.12 EAK87844.1 - 0.023 14.2 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family AAA PF00004.24 EAK87845.1 - 1.6e-45 154.5 0.1 2.9e-44 150.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EAK87845.1 - 2e-09 37.6 0.1 2.7e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EAK87845.1 - 3.9e-09 36.3 0.2 1.7e-08 34.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAK87845.1 - 1.6e-06 28.2 0.6 0.0002 21.4 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAK87845.1 - 1.9e-05 24.7 0.1 8.5e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EAK87845.1 - 2.5e-05 23.3 0.0 5.3e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EAK87845.1 - 7.3e-05 23.5 0.1 0.00063 20.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EAK87845.1 - 9.2e-05 21.5 0.0 0.00027 20.0 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EAK87845.1 - 0.00011 22.2 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EAK87845.1 - 0.00055 19.3 1.7 0.026 13.9 0.1 2.7 2 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EAK87845.1 - 0.00068 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 EAK87845.1 - 0.00069 19.5 0.1 0.0046 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EAK87845.1 - 0.00078 19.7 0.1 0.0092 16.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EAK87845.1 - 0.00084 18.7 0.0 0.0026 17.2 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 EAK87845.1 - 0.00088 18.8 0.1 0.029 13.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EAK87845.1 - 0.00099 18.9 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAK87845.1 - 0.0011 18.6 0.3 0.0026 17.4 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EAK87845.1 - 0.0013 17.5 0.0 0.011 14.5 0.0 2.1 2 1 0 2 2 2 1 TIP49 C-terminus Mg_chelatase PF01078.16 EAK87845.1 - 0.0013 17.9 0.0 0.0031 16.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EAK87845.1 - 0.0015 18.3 0.1 0.018 14.7 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_24 PF13479.1 EAK87845.1 - 0.0035 16.9 0.2 0.0075 15.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EAK87845.1 - 0.0045 16.4 0.1 0.095 12.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_23 PF13476.1 EAK87845.1 - 0.0048 17.2 0.9 3.3 8.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EAK87845.1 - 0.005 15.9 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EAK87845.1 - 0.0059 16.2 0.3 0.08 12.5 0.1 2.3 2 0 0 2 2 2 1 NACHT domain AAA_11 PF13086.1 EAK87845.1 - 0.0066 16.0 0.1 0.03 13.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EAK87845.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EAK87845.1 - 0.013 15.1 0.9 0.23 11.1 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase Parvo_NS1 PF01057.12 EAK87845.1 - 0.022 13.6 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EAK87845.1 - 0.023 13.5 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.1 EAK87845.1 - 0.035 14.1 0.2 0.12 12.4 0.0 2.1 2 1 0 2 2 1 0 Sigma-54 interaction domain KaiC PF06745.8 EAK87845.1 - 0.041 13.0 1.7 0.74 8.8 0.0 2.8 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.1 EAK87845.1 - 0.046 13.2 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3363 PF11843.3 EAK87845.1 - 0.05 12.2 0.0 0.082 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) T2SE PF00437.15 EAK87845.1 - 0.062 12.1 0.0 0.13 11.1 0.0 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EAK87845.1 - 0.064 12.4 0.1 0.18 11.0 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 EAK87845.1 - 0.12 12.6 0.1 0.51 10.6 0.0 2.3 1 1 0 1 1 1 0 ABC transporter FlaC_arch PF05377.6 EAK87845.1 - 1 9.2 3.4 1.1 9.2 1.0 2.1 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) RasGAP PF00616.14 EAK87849.1 - 0.054 13.1 1.8 0.045 13.4 0.7 1.5 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF948 PF06103.6 EAK87849.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) p12I PF12233.3 EAK87849.1 - 0.33 11.2 1.3 0.37 11.0 0.0 1.6 2 0 0 2 2 2 0 Human adult T cell leukemia/lymphoma virus protein NatB_MDM20 PF09797.4 EAK87851.1 - 0.0012 17.6 1.4 0.0015 17.2 1.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit MutS_III PF05192.13 EAK87852.1 - 0.0036 17.1 8.6 1 9.0 6.0 3.5 1 1 0 1 1 1 1 MutS domain III TBCC PF07986.7 EAK87854.1 - 3.2e-31 107.2 2.8 4.5e-31 106.7 1.9 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.6 EAK87854.1 - 0.54 9.5 4.5 0.45 9.8 1.0 1.8 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) C terminal FBA_2 PF07735.12 EAK87854.1 - 1.2 8.9 5.8 3.9 7.4 0.2 3.1 2 2 1 3 3 3 0 F-box associated DUF1024 PF06260.7 EAK87855.1 - 0.012 15.7 0.1 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) Ank_2 PF12796.2 EAK87856.1 - 8.9e-29 99.6 0.1 8.1e-10 38.9 0.0 4.6 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EAK87856.1 - 4.4e-28 95.6 5.1 5e-05 22.8 0.0 6.0 5 1 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EAK87856.1 - 7.8e-24 83.5 0.3 5.2e-05 23.6 0.0 5.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAK87856.1 - 5.7e-22 77.2 0.0 4.8e-05 23.4 0.0 5.0 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAK87856.1 - 2.7e-20 70.4 2.1 0.005 16.9 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat Sushi PF00084.15 EAK87856.1 - 3.1e-07 30.6 1.4 6.3e-07 29.6 0.4 2.0 2 0 0 2 2 2 1 Sushi domain (SCR repeat) TMEM154 PF15102.1 EAK87856.1 - 0.075 12.7 0.2 0.24 11.1 0.2 1.7 2 0 0 2 2 2 0 TMEM154 protein family DUF2970 PF11174.3 EAK87856.1 - 0.25 10.9 2.0 1.8 8.2 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Sigma_reg_N PF13800.1 EAK87856.1 - 0.83 9.7 4.9 2.6 8.1 0.7 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Vps35 PF03635.12 EAK87859.1 - 4.9e-262 871.5 13.5 5.6e-262 871.3 9.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Mon1 PF03164.9 EAK87860.1 - 1.3e-33 116.1 15.0 2.3e-31 108.8 10.4 2.0 1 1 0 1 1 1 1 Trafficking protein Mon1 tRNA-synt_2 PF00152.15 EAK87861.1 - 1.1e-90 303.7 0.1 1.4e-90 303.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EAK87861.1 - 6.6e-09 35.5 0.0 1.8e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EAK87861.1 - 1.3e-06 27.7 0.1 0.017 14.2 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EAK87861.1 - 0.02 14.4 0.0 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) ATPgrasp_Ter PF15632.1 EAK87861.1 - 0.057 12.1 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF4234 PF14018.1 EAK87862.1 - 3.5 7.4 8.0 7 6.4 1.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) Claudin_3 PF06653.6 EAK87863.1 - 0.063 13.0 2.7 0.34 10.6 1.9 2.0 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Cyclin PF08613.6 EAK87863.1 - 0.12 12.7 0.6 0.17 12.2 0.4 1.4 1 1 0 1 1 1 0 Cyclin CcoS PF03597.10 EAK87863.1 - 0.2 11.1 7.5 0.071 12.5 2.3 2.1 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Met_gamma_lyase PF06838.6 EAK87864.1 - 0.11 10.8 0.1 0.15 10.3 0.1 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase CENP-F_leu_zip PF10473.4 EAK87864.1 - 0.2 11.5 8.3 0.45 10.3 1.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 EAK87864.1 - 0.33 10.7 4.2 0.63 9.8 0.3 2.5 2 0 0 2 2 2 0 Prefoldin subunit DivIC PF04977.10 EAK87864.1 - 0.42 10.1 4.4 0.24 10.9 0.1 2.7 3 0 0 3 3 3 0 Septum formation initiator TSC22 PF01166.13 EAK87864.1 - 1.5 8.8 4.8 15 5.6 0.0 3.2 3 1 0 3 3 3 0 TSC-22/dip/bun family DUF2711 PF10924.3 EAK87866.1 - 0.021 14.2 0.1 0.032 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) DUF1647 PF07801.6 EAK87866.1 - 0.073 12.5 0.2 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) DFP PF04127.10 EAK87868.1 - 1e-14 54.5 0.0 3.4e-06 26.8 0.0 2.8 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Dpy19 PF10034.4 EAK87869.1 - 3.8e-209 696.0 49.0 5.5e-209 695.5 34.0 1.2 1 0 0 1 1 1 1 Q-cell neuroblast polarisation TPR_17 PF13431.1 EAK87869.1 - 0.0045 17.0 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Asp PF00026.18 EAK87870.1 - 2e-15 56.8 3.5 7.2e-15 55.0 2.4 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAK87870.1 - 1.9e-13 50.6 0.0 9.5e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EAK87870.1 - 2.4e-06 27.1 0.0 5.6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal RVP PF00077.15 EAK87870.1 - 0.0095 15.8 0.2 0.42 10.5 0.0 3.2 3 0 0 3 3 3 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EAK87870.1 - 0.028 14.9 0.1 0.73 10.3 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease dsDNA_bind PF01984.15 EAK87871.1 - 3.7e-16 59.0 1.1 4.5e-16 58.7 0.8 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF825 PF05695.7 EAK87871.1 - 0.066 10.6 2.5 0.075 10.4 1.7 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) DLD PF14878.1 EAK87871.1 - 0.082 13.0 0.3 1.1 9.3 0.1 2.1 1 1 1 2 2 2 0 Death-like domain of SPT6 CDT1 PF08839.6 EAK87874.1 - 5.5e-49 166.2 3.4 5.5e-49 166.2 2.4 3.2 3 0 0 3 3 3 1 DNA replication factor CDT1 like SET PF00856.23 EAK87875.1 - 1.6e-09 38.2 0.7 3.3e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 SET domain PX PF00787.19 EAK87876.1 - 4.3e-22 78.0 1.5 5.7e-22 77.6 0.1 1.9 2 0 0 2 2 2 1 PX domain RabGAP-TBC PF00566.13 EAK87877.1 - 1.5e-29 103.0 0.9 1.5e-29 103.0 0.6 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3732 PF12532.3 EAK87878.1 - 0.015 14.8 0.3 0.027 13.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) Fib_alpha PF08702.5 EAK87878.1 - 0.063 13.4 1.2 0.082 13.0 0.9 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CobU PF02283.11 EAK87878.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Rad51 PF08423.6 EAK87878.1 - 0.17 10.7 1.0 0.37 9.6 0.2 2.1 2 1 0 2 2 2 0 Rad51 Cyclin_N PF00134.18 EAK87879.1 - 1.1e-08 34.6 2.0 1.1e-08 34.6 1.4 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EAK87879.1 - 5.6e-06 26.2 0.4 2.1e-05 24.4 0.2 2.0 1 0 0 1 1 1 1 Cyclin, C-terminal domain VID27 PF08553.5 EAK87880.1 - 2.8e-56 191.2 3.0 3.7e-56 190.8 2.1 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein CDC73 PF05179.9 EAK87881.1 - 3.9e-39 134.6 0.7 6.3e-39 133.9 0.5 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Nop52 PF05997.7 EAK87883.1 - 4.6e-56 189.6 3.9 4.6e-56 189.6 2.7 1.9 2 0 0 2 2 2 1 Nucleolar protein,Nop52 RabGAP-TBC PF00566.13 EAK87884.1 - 7e-62 208.6 2.1 1.2e-61 207.9 1.4 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SPATA6 PF14909.1 EAK87884.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 tRNA_anti_2 PF13742.1 EAK87884.1 - 0.099 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain ODV-E18 PF10717.4 EAK87885.1 - 0.026 13.9 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Rifin_STEVOR PF02009.11 EAK87885.1 - 0.033 13.8 0.2 0.041 13.5 0.1 1.0 1 0 0 1 1 1 0 Rifin/stevor family BatD PF13584.1 EAK87885.1 - 0.045 12.3 0.1 0.056 12.0 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF3834 PF12916.2 EAK87885.1 - 0.046 12.7 0.1 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) DUF1183 PF06682.7 EAK87885.1 - 0.065 12.8 0.1 0.081 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF676 PF05057.9 EAK87886.1 - 1.2e-23 83.5 0.0 6.5e-23 81.1 0.0 2.1 1 1 0 1 1 1 1 Putative serine esterase (DUF676) KIP1 PF07765.7 EAK87886.1 - 0.0037 17.0 0.9 0.0066 16.2 0.1 1.9 2 0 0 2 2 2 1 KIP1-like protein Abhydrolase_5 PF12695.2 EAK87886.1 - 0.022 14.5 0.0 0.066 12.9 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 EAK87886.1 - 0.055 13.0 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.2 EAK87886.1 - 0.25 11.2 0.0 1.5 8.6 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Exo_endo_phos PF03372.18 EAK87887.1 - 5.2e-21 75.6 0.0 1.6e-20 74.1 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family ORC2 PF04084.9 EAK87888.1 - 6.7e-44 150.0 11.3 7.9e-44 149.8 7.9 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DUF3407 PF11887.3 EAK87888.1 - 0.18 11.0 0.8 0.34 10.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) SNARE PF05739.14 EAK87889.1 - 0.0013 18.3 2.4 0.0013 18.3 1.7 2.5 3 0 0 3 3 3 1 SNARE domain DUF2278 PF10042.4 EAK87889.1 - 0.039 13.6 2.2 0.047 13.4 1.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) Phage_tail PF04630.7 EAK87889.1 - 0.074 12.1 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Phage major tail protein Syntaxin-6_N PF09177.6 EAK87889.1 - 0.26 11.7 0.3 0.26 11.7 0.2 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Endonuc_subdom PF09062.5 EAK87889.1 - 0.28 11.9 2.5 0.33 11.7 1.2 1.5 1 1 0 1 1 1 0 PI-PfuI Endonuclease subdomain Myb_DNA-bind_3 PF12776.2 EAK87889.1 - 0.28 11.8 3.4 0.23 12.0 0.4 2.0 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain YfhO PF09586.5 EAK87889.1 - 2.6 5.9 5.9 1.9 6.4 3.4 1.3 1 1 0 1 1 1 0 Bacterial membrane protein YfhO DUF2531 PF10748.4 EAK87891.1 - 0.04 13.1 0.1 0.089 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2531) A_deaminase PF00962.17 EAK87892.1 - 9.4e-85 284.4 0.0 1.1e-83 280.8 0.0 2.1 2 0 0 2 2 2 1 Adenosine/AMP deaminase DUF1965 PF09248.5 EAK87892.1 - 0.008 16.0 0.6 0.037 13.9 0.4 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) DUF865 PF05906.6 EAK87892.1 - 0.038 13.5 0.1 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus-7 repeat of unknown function (DUF865) Exo_endo_phos PF03372.18 EAK87894.1 - 4.3e-11 43.2 0.0 8.2e-11 42.3 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SPASM PF13186.1 EAK87894.1 - 0.59 10.5 4.7 13 6.1 0.1 3.4 3 0 0 3 3 3 0 Iron-sulfur cluster-binding domain zf-C3HC4_3 PF13920.1 EAK87895.1 - 5.7e-08 32.3 2.2 1.2e-07 31.2 1.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK87895.1 - 5.8e-05 23.0 6.6 0.00012 22.0 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAK87895.1 - 7e-05 22.5 6.3 0.00014 21.6 4.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EAK87895.1 - 0.00022 20.8 4.7 0.00045 19.8 3.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EAK87895.1 - 0.00057 19.4 7.7 0.0013 18.3 5.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAK87895.1 - 0.0024 17.5 2.3 0.0066 16.1 1.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EAK87895.1 - 0.0042 16.6 7.8 0.0083 15.6 5.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Cas_CXXC_CXXC PF09706.5 EAK87895.1 - 1.6 8.9 7.4 0.37 11.0 0.4 3.2 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-C3HC4_4 PF15227.1 EAK87895.1 - 2 8.3 7.4 5.6 6.9 5.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Tctex-1 PF03645.8 EAK87898.1 - 5.4e-28 96.8 1.4 6.5e-28 96.5 0.9 1.1 1 0 0 1 1 1 1 Tctex-1 family KAR PF15222.1 EAK87898.1 - 0.017 15.2 1.4 0.037 14.0 0.7 1.7 1 1 1 2 2 2 0 Kidney androgen-regulated DELLA PF12041.3 EAK87898.1 - 0.028 14.0 0.1 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal Mating_N PF12731.2 EAK87898.1 - 0.12 12.2 0.2 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Mating-type protein beta 1 AIM24 PF01987.12 EAK87901.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial biogenesis AIM24 DUF747 PF05346.6 EAK87902.1 - 1.6e-08 33.9 2.2 1.8e-08 33.8 1.5 1.0 1 0 0 1 1 1 1 Eukaryotic membrane protein family O-antigen_lig PF13425.1 EAK87902.1 - 0.21 11.5 4.9 0.24 11.3 3.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF747 PF05346.6 EAK87903.1 - 3.1e-81 273.0 22.9 3.1e-81 273.0 15.9 1.7 2 0 0 2 2 2 1 Eukaryotic membrane protein family PGAP1 PF07819.8 EAK87904.1 - 1.8e-09 37.5 2.0 2.4e-09 37.1 0.6 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EAK87904.1 - 0.036 13.9 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Cnd1 PF12717.2 EAK87905.1 - 8.2e-32 110.4 10.4 8.2e-32 110.4 7.2 6.4 4 1 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Brr6_like_C_C PF10104.4 EAK87906.1 - 5.6e-44 148.9 14.4 6e-44 148.8 6.5 2.2 2 0 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain Colicin_V PF02674.11 EAK87906.1 - 0.98 9.2 9.6 2.5 7.9 1.2 2.2 2 0 0 2 2 2 0 Colicin V production protein Myosin_head PF00063.16 EAK87907.1 - 5.3e-123 411.4 24.1 3.3e-97 326.2 9.2 2.8 2 0 0 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.1 EAK87907.1 - 0.0074 16.4 0.0 0.026 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAK87907.1 - 0.33 10.7 0.0 0.67 9.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EAK87907.1 - 0.38 10.7 0.0 0.38 10.7 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain DUF3487 PF11990.3 EAK87908.1 - 1 8.7 5.7 2 7.8 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF4392 PF14336.1 EAK87909.1 - 1.8e-56 191.1 0.0 2.1e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) DUF3369 PF11849.3 EAK87911.1 - 0.026 14.4 6.9 0.026 14.4 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3369) Pkinase PF00069.20 EAK87912.1 - 5.4e-44 150.2 5.4 2.9e-43 147.9 3.7 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK87912.1 - 9e-27 93.7 0.3 2.1e-26 92.5 0.2 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase SNF2_N PF00176.18 EAK87914.1 - 1.7e-66 224.0 0.0 2.7e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EAK87914.1 - 2.3e-16 59.4 0.0 5.3e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EAK87914.1 - 7.3e-15 54.6 0.0 2.1e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 EAK87914.1 - 5.9e-12 45.0 0.2 1e-05 25.0 0.0 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 EAK87914.1 - 0.0001 21.8 0.0 0.11 11.9 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Spb1_C PF07780.7 EAK87915.1 - 1.1e-64 217.9 24.8 1.1e-64 217.9 17.2 5.0 3 1 2 5 5 5 1 Spb1 C-terminal domain FtsJ PF01728.14 EAK87915.1 - 3.8e-55 186.6 0.1 1.1e-54 185.1 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EAK87915.1 - 1.3e-31 109.2 22.4 1.3e-31 109.2 15.5 8.0 5 3 3 8 8 8 1 Domain of unknown function (DUF3381) SRP40_C PF05022.7 EAK87916.1 - 1.2e-24 86.6 5.8 1.2e-24 86.6 4.0 2.6 2 1 0 2 2 2 1 SRP40, C-terminal domain DUF4159 PF13709.1 EAK87916.1 - 0.049 12.7 0.1 0.093 11.8 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4159) DUF1528 PF07515.6 EAK87916.1 - 2.5 8.1 8.7 1.1 9.3 2.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1528) Cpn60_TCP1 PF00118.19 EAK87917.1 - 1.3e-146 489.0 3.9 1.5e-146 488.8 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 EAK87918.1 - 5.4e-154 513.4 1.7 6.2e-154 513.2 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DeoC PF01791.4 EAK87918.1 - 0.049 12.9 0.0 0.38 10.0 0.0 2.3 2 0 0 2 2 2 0 DeoC/LacD family aldolase TPR_11 PF13414.1 EAK87919.1 - 1.5e-12 46.9 3.2 3.6e-09 36.1 0.2 3.4 2 1 2 4 4 4 3 TPR repeat TPR_2 PF07719.12 EAK87919.1 - 1.2e-08 34.1 2.4 0.0027 17.4 0.1 4.4 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EAK87919.1 - 0.00018 21.0 5.5 2.8 7.9 0.1 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EAK87919.1 - 0.00021 20.7 5.5 0.53 9.9 0.3 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAK87919.1 - 0.028 14.3 0.3 0.17 11.8 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 EAK87920.1 - 2.3e-23 81.1 9.8 3.7e-10 39.2 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EAK87920.1 - 2.8e-20 71.9 0.4 1.1e-19 70.1 0.1 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EAK87920.1 - 0.0024 17.5 0.1 0.0063 16.2 0.1 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Histone PF00125.19 EAK87921.1 - 2.8e-32 110.6 0.4 5e-32 109.8 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EAK87921.1 - 0.00016 21.7 0.0 0.00025 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EAK87921.1 - 0.036 14.1 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DEAD PF00270.24 EAK87922.1 - 6.3e-44 149.4 0.1 1e-43 148.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK87922.1 - 1.8e-24 85.3 0.0 4.4e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAK87922.1 - 0.00043 20.1 0.0 0.0014 18.4 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Alg6_Alg8 PF03155.10 EAK87923.1 - 3.7e-97 326.0 38.9 2.4e-95 320.1 27.0 2.0 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WD40 PF00400.27 EAK87924.1 - 2.6e-35 119.0 17.5 1.9e-09 37.0 0.7 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EAK87924.1 - 0.012 13.8 2.9 0.14 10.2 0.6 3.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 NHL PF01436.16 EAK87924.1 - 0.056 13.4 0.3 1.7 8.7 0.0 3.0 3 0 0 3 3 3 0 NHL repeat PQQ_3 PF13570.1 EAK87924.1 - 0.15 12.3 0.3 30 5.0 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain Ribosomal_S27 PF01599.14 EAK87925.1 - 5e-25 87.0 1.8 8.4e-25 86.3 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 EAK87925.1 - 5.4e-07 28.9 0.0 1.8e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family zf-C2H2_3 PF13878.1 EAK87925.1 - 0.0048 16.4 0.1 0.0099 15.4 0.1 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO IBR PF01485.16 EAK87925.1 - 0.018 14.9 0.7 0.028 14.2 0.5 1.3 1 0 0 1 1 1 0 IBR domain PB1 PF00564.19 EAK87925.1 - 0.02 14.5 0.2 0.054 13.1 0.0 1.8 2 0 0 2 2 2 0 PB1 domain Fer2_3 PF13085.1 EAK87925.1 - 0.023 14.5 0.1 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain CRAL_TRIO_2 PF13716.1 EAK87926.1 - 5.8e-27 94.4 0.5 5.8e-27 94.4 0.4 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EAK87926.1 - 2.7e-18 66.0 0.0 2.7e-18 66.0 0.0 2.1 3 0 0 3 3 3 1 RhoGAP domain DUF1708 PF08101.6 EAK87926.1 - 0.00071 18.5 0.1 0.0011 17.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) CRAL_TRIO PF00650.15 EAK87926.1 - 0.033 13.6 0.3 0.13 11.7 0.2 1.9 1 1 0 1 1 1 0 CRAL/TRIO domain Sof1 PF04158.9 EAK87926.1 - 0.043 13.8 0.5 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Sof1-like domain ERCC4 PF02732.10 EAK87927.1 - 1.3e-21 76.8 0.2 3.6e-21 75.4 0.1 1.7 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.1 EAK87927.1 - 0.02 15.0 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Peptidase_M24 PF00557.19 EAK87928.1 - 5.8e-37 127.2 0.0 9.2e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EAK87928.1 - 1.1e-19 71.2 0.0 3e-18 66.5 0.0 2.5 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain DUF2121 PF09894.4 EAK87928.1 - 6.9e-05 22.2 0.2 0.00017 20.9 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2121) Tubulin PF00091.20 EAK87929.1 - 1.2e-70 237.7 0.0 1.7e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EAK87929.1 - 7.7e-51 171.3 0.2 2.1e-50 170.0 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EAK87929.1 - 0.026 13.9 0.0 0.06 12.8 0.0 1.7 2 0 0 2 2 2 0 Tubulin domain EMG1 PF03587.9 EAK87930.1 - 9e-56 188.3 0.2 1e-55 188.1 0.1 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase EMG1 PF03587.9 EAK87931.1 - 6.8e-45 152.8 0.1 7.6e-45 152.6 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase SPOUT_MTase PF02590.12 EAK87931.1 - 0.0082 15.8 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase CTDII PF01556.13 EAK87932.1 - 5.3e-29 99.9 0.6 3.1e-24 84.6 0.1 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EAK87932.1 - 2.9e-27 94.1 2.1 5.3e-27 93.3 1.5 1.5 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 EAK87932.1 - 0.074 12.4 0.0 0.39 10.1 0.0 2.2 2 1 0 2 2 2 0 A repeated domain in UCH-protein TB PF00683.12 EAK87932.1 - 0.18 11.4 2.2 0.48 10.0 1.3 1.8 2 0 0 2 2 2 0 TB domain DnaJ_CXXCXGXG PF00684.14 EAK87932.1 - 0.53 10.3 3.4 1 9.4 2.4 1.4 1 0 0 1 1 1 0 DnaJ central domain Bax1-I PF01027.15 EAK87933.1 - 1.3e-35 122.9 37.1 1.5e-35 122.6 25.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.6 EAK87933.1 - 7.1 6.2 42.1 3.8 7.1 27.3 1.9 1 1 0 1 1 1 0 7TM diverse intracellular signalling polyprenyl_synt PF00348.12 EAK87934.1 - 4.2e-35 120.8 0.0 5.9e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase ubiquitin PF00240.18 EAK87935.1 - 3e-17 61.7 0.1 4.9e-17 61.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EAK87935.1 - 1.1e-08 34.6 0.0 1.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 EAK87935.1 - 4.2e-07 29.6 0.0 1.2e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD_2 PF13881.1 EAK87935.1 - 0.00013 21.7 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EAK87935.1 - 0.00034 20.7 0.1 0.00077 19.6 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain CUE PF02845.11 EAK87935.1 - 0.0013 18.1 0.9 0.0046 16.4 0.0 2.5 3 0 0 3 3 3 1 CUE domain HSP90 PF00183.13 EAK87935.1 - 0.0093 14.4 0.1 0.013 13.9 0.1 1.1 1 0 0 1 1 1 1 Hsp90 protein ThiF PF00899.16 EAK87936.1 - 2.9e-51 172.8 1.4 2.6e-35 121.2 0.0 3.0 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 EAK87936.1 - 3.7e-34 117.5 0.1 9.8e-34 116.2 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EAK87936.1 - 5.1e-28 96.4 3.1 1.8e-23 81.8 0.0 3.3 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EAK87936.1 - 8e-20 69.9 0.5 8e-20 69.9 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site ATP_transf PF09830.4 EAK87936.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 ATP adenylyltransferase AD PF09793.4 EAK87937.1 - 1.8e-23 82.1 0.2 9.7e-23 79.8 0.0 1.9 1 1 1 2 2 2 1 Anticodon-binding domain Gemin6 PF06372.7 EAK87937.1 - 0.00098 18.4 0.3 0.0077 15.5 0.0 2.0 1 1 1 2 2 2 1 Gemin6 protein Ribosomal_L10 PF00466.15 EAK87938.1 - 2.3e-22 78.7 0.1 5.1e-22 77.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EAK87938.1 - 2.1e-10 40.8 0.2 8.2e-10 38.9 0.1 2.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein S19 PF06756.6 EAK87938.1 - 0.036 13.9 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Chorion protein S19 C-terminal Adaptin_N PF01602.15 EAK87940.1 - 2.5e-70 237.3 30.1 4e-70 236.6 20.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EAK87940.1 - 0.00017 21.8 0.1 1 9.7 0.1 3.5 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EAK87940.1 - 0.0014 18.5 0.7 4.7 7.5 0.1 4.0 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EAK87940.1 - 0.13 12.8 0.0 35 5.0 0.0 2.8 2 0 0 2 2 2 0 HEAT-like repeat PIGA PF08288.7 EAK87941.1 - 1.6e-41 140.5 1.6 5.2e-41 138.9 0.7 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EAK87941.1 - 1.8e-29 102.3 0.0 3.2e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EAK87941.1 - 3.7e-18 65.8 0.1 6.8e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EAK87941.1 - 9.7e-12 45.1 0.0 1.8e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EAK87941.1 - 3.7e-11 43.4 0.0 5.4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EAK87941.1 - 0.00018 21.3 0.2 0.00049 19.9 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EAK87941.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 zf-DHHC PF01529.15 EAK87942.1 - 1.7e-27 95.9 18.7 1.7e-27 95.9 13.0 2.4 1 1 1 2 2 2 1 DHHC palmitoyltransferase zf-C2H2 PF00096.21 EAK87943.1 - 1.4 9.3 7.9 0.52 10.7 1.2 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Histone PF00125.19 EAK87944.1 - 2.2e-23 82.1 0.0 2.7e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAK87944.1 - 0.0014 18.6 0.0 0.0043 17.0 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 EAK87944.1 - 0.079 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) ThiF PF00899.16 EAK87945.1 - 1.2e-34 119.0 0.4 2.4e-34 118.1 0.3 1.5 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 EAK87945.1 - 0.011 14.7 0.7 0.041 12.8 0.2 2.0 2 1 0 2 2 2 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EAK87945.1 - 0.025 14.6 0.1 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EAK87945.1 - 0.038 13.9 0.5 0.15 12.0 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain RNase_PH PF01138.16 EAK87946.1 - 1.6e-17 64.0 0.0 3e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NDK PF00334.14 EAK87947.1 - 4.9e-53 178.5 0.0 5.7e-53 178.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DEAD PF00270.24 EAK87948.1 - 3.4e-35 121.0 0.3 1.7e-34 118.7 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK87948.1 - 1.1e-20 73.2 0.0 3.6e-20 71.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EAK87948.1 - 3e-14 52.3 0.1 7.2e-14 51.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EAK87948.1 - 0.0059 16.4 0.0 0.0059 16.4 0.0 4.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA PF00004.24 EAK87949.1 - 5.2e-81 269.3 0.2 1.8e-48 164.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EAK87949.1 - 7.8e-12 45.4 0.0 6.5e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EAK87949.1 - 8.4e-12 44.6 0.0 0.00014 20.9 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EAK87949.1 - 3.7e-10 39.6 0.8 0.0024 17.5 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAK87949.1 - 4.3e-09 36.6 0.5 0.0033 17.4 0.0 3.8 4 1 1 5 5 4 2 AAA ATPase domain AAA_14 PF13173.1 EAK87949.1 - 4.6e-09 36.2 5.5 0.00067 19.5 0.1 4.4 4 1 1 5 5 4 2 AAA domain TIP49 PF06068.8 EAK87949.1 - 1.1e-08 34.2 0.9 0.0067 15.1 0.0 3.5 2 1 1 3 3 3 2 TIP49 C-terminus AAA_17 PF13207.1 EAK87949.1 - 3.1e-08 34.4 0.1 0.00019 22.2 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EAK87949.1 - 5.6e-07 29.7 10.7 0.0014 18.7 0.2 5.3 3 2 1 4 4 4 2 AAA domain RNA_helicase PF00910.17 EAK87949.1 - 1.4e-06 28.3 0.1 0.039 14.1 0.0 3.8 3 0 0 3 3 3 2 RNA helicase IstB_IS21 PF01695.12 EAK87949.1 - 3.6e-06 26.5 0.0 0.018 14.4 0.0 3.0 2 1 1 3 3 3 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EAK87949.1 - 8.2e-06 25.1 0.0 0.02 14.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EAK87949.1 - 3.8e-05 23.3 0.2 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 EAK87949.1 - 0.00016 21.9 0.0 0.14 12.4 0.0 2.8 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.1 EAK87949.1 - 0.00019 21.3 0.0 0.46 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 EAK87949.1 - 0.00036 20.1 0.5 0.089 12.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EAK87949.1 - 0.00036 20.8 3.1 0.0014 18.9 0.0 3.6 3 1 1 4 4 4 1 AAA domain AAA_3 PF07726.6 EAK87949.1 - 0.00056 19.5 0.0 0.93 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EAK87949.1 - 0.00057 19.5 0.0 0.063 12.9 0.0 3.6 3 1 0 3 3 3 1 NACHT domain Sigma54_activ_2 PF14532.1 EAK87949.1 - 0.00096 19.2 0.0 1.6 8.7 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain KaiC PF06745.8 EAK87949.1 - 0.0011 18.1 0.4 0.49 9.4 0.0 3.0 3 0 0 3 3 2 1 KaiC DUF2075 PF09848.4 EAK87949.1 - 0.0015 17.6 0.4 0.0049 15.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 EAK87949.1 - 0.0016 17.9 0.0 0.84 9.0 0.0 2.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EAK87949.1 - 0.002 17.0 0.0 0.061 12.1 0.0 2.5 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 EAK87949.1 - 0.0032 16.5 0.0 2.4 7.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EAK87949.1 - 0.0047 16.3 3.2 0.67 9.3 0.0 3.9 2 2 1 4 4 4 1 AAA domain PhoH PF02562.11 EAK87949.1 - 0.013 14.7 0.0 1.3 8.2 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.1 EAK87949.1 - 0.02 14.4 0.9 0.72 9.3 0.0 3.0 4 0 0 4 4 2 0 AAA domain AAA_28 PF13521.1 EAK87949.1 - 0.053 13.4 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 EAK87949.1 - 0.055 13.3 0.1 3.6 7.4 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase UPF0079 PF02367.12 EAK87949.1 - 0.067 12.8 0.0 1.9 8.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 EAK87949.1 - 0.071 12.6 0.0 6.7 6.1 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NOG1 PF06858.9 EAK87950.1 - 3.3e-26 90.9 0.6 1.7e-25 88.6 0.3 2.4 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EAK87950.1 - 4.1e-25 87.2 3.4 8.8e-25 86.1 2.4 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EAK87950.1 - 4.6e-18 65.2 0.0 1.8e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAK87950.1 - 3.2e-10 39.5 0.0 9.9e-10 37.9 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EAK87950.1 - 0.00094 18.3 0.0 0.0018 17.4 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EAK87950.1 - 0.0032 17.9 0.0 0.017 15.6 0.0 2.4 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EAK87950.1 - 0.0042 16.9 2.7 1.2 8.8 0.0 3.2 3 1 1 4 4 4 2 Dynamin family AIG1 PF04548.11 EAK87950.1 - 0.022 13.8 0.1 0.094 11.8 0.0 2.1 2 0 0 2 2 2 0 AIG1 family DUF258 PF03193.11 EAK87950.1 - 0.054 12.6 0.0 0.37 9.9 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Thioredoxin PF00085.15 EAK87951.1 - 7.7e-27 93.0 0.1 8.9e-27 92.8 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EAK87951.1 - 6.6e-06 26.1 0.0 7.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EAK87951.1 - 0.002 17.8 0.1 0.0022 17.6 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 EAK87951.1 - 0.0046 17.1 0.2 0.1 12.8 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EAK87951.1 - 0.01 15.4 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.1 EAK87951.1 - 0.052 13.1 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin SART-1 PF03343.8 EAK87952.1 - 9.9e-27 93.5 53.2 2.6e-26 92.1 36.9 1.6 1 1 0 1 1 1 1 SART-1 family Sec20 PF03908.8 EAK87953.1 - 4.2e-05 23.1 0.8 6.9e-05 22.4 0.5 1.4 1 1 0 1 1 1 1 Sec20 SNARE PF05739.14 EAK87953.1 - 0.0013 18.3 0.7 0.0017 17.9 0.5 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EAK87953.1 - 0.0077 15.7 0.8 0.0089 15.4 0.6 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF1664 PF07889.7 EAK87953.1 - 0.044 13.5 0.1 0.057 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ArsR PF09824.4 EAK87953.1 - 0.045 13.0 0.1 0.057 12.7 0.1 1.1 1 0 0 1 1 1 0 ArsR transcriptional regulator Rab5-bind PF09311.6 EAK87953.1 - 0.097 12.5 0.1 0.1 12.4 0.1 1.0 1 0 0 1 1 1 0 Rabaptin-like protein Pol_alpha_B_N PF08418.5 EAK87953.1 - 0.14 11.6 0.3 0.18 11.3 0.2 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Ribosomal_L31e PF01198.14 EAK87954.1 - 7.6e-36 121.6 1.0 8.9e-36 121.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Thioredoxin PF00085.15 EAK87955.1 - 8.1e-12 44.7 0.0 1.5e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DUF1510 PF07423.6 EAK87955.1 - 1.8e-07 30.7 31.0 1.8e-07 30.7 21.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 EAK87955.1 - 2.3e-05 22.3 17.3 2.3e-05 22.3 12.0 1.5 2 0 0 2 2 2 1 Ycf1 Trypan_PARP PF05887.6 EAK87955.1 - 0.00012 21.9 36.4 0.00022 21.0 25.2 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Thioredoxin_2 PF13098.1 EAK87955.1 - 0.028 14.5 0.0 0.11 12.7 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain K1 PF02960.9 EAK87955.1 - 0.034 14.1 0.1 0.084 12.9 0.0 1.6 2 0 0 2 2 1 0 K1 glycoprotein IncA PF04156.9 EAK87955.1 - 0.045 13.3 17.3 0.099 12.2 12.0 1.6 1 0 0 1 1 1 0 IncA protein Erf4 PF10256.4 EAK87955.1 - 0.064 13.1 0.7 0.62 9.9 0.1 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Neur_chan_memb PF02932.11 EAK87955.1 - 0.098 12.5 9.2 0.019 14.8 3.5 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Nop14 PF04147.7 EAK87955.1 - 0.11 10.4 57.3 0.16 9.8 39.7 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2201_N PF13203.1 EAK87955.1 - 0.13 11.3 12.0 0.22 10.6 8.3 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain PA26 PF04636.8 EAK87955.1 - 0.17 10.5 10.9 0.27 9.8 7.5 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) LMBR1 PF04791.11 EAK87955.1 - 0.31 9.5 8.0 0.47 8.9 5.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SDA1 PF05285.7 EAK87955.1 - 0.44 9.7 51.6 0.7 9.1 35.8 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 EAK87955.1 - 1.2 7.0 41.9 1.8 6.4 29.1 1.2 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 EAK87955.1 - 1.4 8.0 34.1 2.2 7.4 23.7 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Spore_coat_CotO PF14153.1 EAK87955.1 - 1.9 7.9 43.9 0.12 11.8 26.6 1.8 2 0 0 2 2 2 0 Spore coat protein CotO Na_trans_assoc PF06512.8 EAK87955.1 - 3.5 7.5 32.7 0.43 10.4 19.1 2.0 2 0 0 2 2 2 0 Sodium ion transport-associated RR_TM4-6 PF06459.7 EAK87955.1 - 4.9 6.9 36.2 11 5.7 25.1 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 EAK87955.1 - 5.7 6.8 14.9 0.34 10.8 6.7 1.7 2 0 0 2 2 2 0 GAGA binding protein-like family Utp14 PF04615.8 EAK87955.1 - 6.7 4.7 51.1 2.4 6.2 33.1 1.7 2 0 0 2 2 2 0 Utp14 protein Glycos_transf_4 PF00953.16 EAK87956.1 - 1.4e-33 115.9 13.9 1.4e-33 115.9 9.7 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 4 DUF4022 PF13214.1 EAK87957.1 - 0.028 14.5 1.6 0.046 13.8 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4022) DUF1240 PF06836.7 EAK87958.1 - 0.018 15.2 3.0 0.032 14.4 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) Actin PF00022.14 EAK87959.1 - 1.1e-123 412.5 0.0 1.4e-123 412.2 0.0 1.0 1 0 0 1 1 1 1 Actin SET PF00856.23 EAK87960.1 - 2.3e-07 31.2 0.1 2.9e-05 24.4 0.0 3.1 2 1 0 2 2 2 1 SET domain SPOB_ab PF14682.1 EAK87960.1 - 0.084 12.6 0.3 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal UCH PF00443.24 EAK87961.1 - 3.6e-26 91.8 9.6 7.8e-26 90.7 6.7 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EAK87961.1 - 1e-08 35.1 3.0 2.6e-08 33.8 2.1 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein PRE_C2HC PF07530.6 EAK87961.1 - 0.11 12.3 0.3 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Associated with zinc fingers Ribosomal_60s PF00428.14 EAK87962.1 - 2.1e-20 72.8 5.2 3.2e-20 72.2 3.6 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein Surface_antigen PF11054.3 EAK87962.1 - 0.0096 15.3 0.7 0.011 15.1 0.0 1.4 2 0 0 2 2 2 1 Sporozoite TA4 surface antigen Peptidase_M50B PF13398.1 EAK87962.1 - 0.062 12.6 0.2 0.081 12.2 0.1 1.1 1 0 0 1 1 1 0 Peptidase M50B-like SIT PF15330.1 EAK87963.1 - 0.34 11.0 0.0 0.34 11.0 0.0 3.0 3 1 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT TFIIF_alpha PF05793.7 EAK87963.1 - 9.4 4.4 37.6 16 3.7 26.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Gcd10p PF04189.8 EAK87964.1 - 7.8e-24 84.3 9.3 7.8e-24 84.3 6.4 2.4 2 1 0 2 2 2 1 Gcd10p family Methyltransf_31 PF13847.1 EAK87964.1 - 0.016 14.7 2.3 0.018 14.6 0.4 2.0 2 0 0 2 2 2 0 Methyltransferase domain ABC1 PF03109.11 EAK87965.1 - 1.9e-29 102.0 0.1 3.2e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 EAK87965.1 - 0.00046 19.4 2.3 0.0015 17.7 1.6 1.8 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAK87965.1 - 0.055 13.1 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Dus PF01207.12 EAK87967.1 - 2.5e-42 144.8 0.0 4.6e-21 74.9 0.0 3.2 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) RRM_1 PF00076.17 EAK87969.1 - 6.7e-08 32.0 0.0 1.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK87969.1 - 1.7e-06 27.9 0.0 7.3e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK87969.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GCD14 PF08704.5 EAK87970.1 - 9.9e-61 205.3 0.3 6.5e-59 199.4 0.0 2.1 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EAK87970.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EAK87970.1 - 0.0005 19.1 0.0 0.00081 18.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 EAK87970.1 - 0.00054 19.5 0.0 0.00096 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.1 EAK87970.1 - 0.001 18.6 0.0 0.0022 17.4 0.0 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_18 PF12847.2 EAK87970.1 - 0.0021 18.5 0.0 0.0036 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EAK87970.1 - 0.0022 17.0 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Rad60-SLD PF11976.3 EAK87972.1 - 8.3e-11 41.4 0.0 8.5e-09 34.9 0.0 3.0 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like F-box-like PF12937.2 EAK87972.1 - 0.002 17.7 1.5 0.005 16.5 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAK87972.1 - 0.0093 15.6 0.2 0.034 13.7 0.1 2.0 1 0 0 1 1 1 1 F-box domain ubiquitin PF00240.18 EAK87972.1 - 0.027 13.8 0.0 0.075 12.4 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin family UCH PF00443.24 EAK87973.1 - 3e-40 138.0 8.7 6.4e-40 136.9 2.7 4.7 4 1 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAK87973.1 - 7.3e-09 35.4 4.9 7.3e-09 35.4 3.4 4.9 5 0 0 5 5 5 2 Ubiquitin carboxyl-terminal hydrolase PAT1 PF09770.4 EAK87973.1 - 0.00012 20.4 86.4 0.00012 20.4 59.9 2.2 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.11 EAK87973.1 - 3.3 6.1 15.9 6.8 5.1 11.0 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein CECR6_TMEM121 PF14997.1 EAK87974.1 - 5.8e-13 48.8 5.5 5.8e-13 48.8 3.8 2.2 2 0 0 2 2 2 1 CECR6/TMEM121 family WD40 PF00400.27 EAK87975.1 - 5.7e-18 64.0 10.5 0.00015 21.4 0.0 8.5 9 0 0 9 9 9 5 WD domain, G-beta repeat DNA_mis_repair PF01119.14 EAK87976.1 - 3.1e-18 65.3 0.1 1.1e-17 63.6 0.1 2.0 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EAK87976.1 - 3.2e-12 46.2 1.7 6.5e-12 45.2 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EAK87976.1 - 1.7e-09 37.3 0.1 6.6e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-C2H2_4 PF13894.1 EAK87978.1 - 0.015 15.5 0.4 0.87 10.0 0.1 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EAK87978.1 - 0.15 12.0 0.5 0.15 12.0 0.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAK87978.1 - 0.2 11.8 0.4 0.2 11.8 0.3 3.3 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EAK87978.1 - 0.28 11.6 2.0 1.9 9.0 0.2 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EAK87978.1 - 1.9 8.6 8.4 0.17 12.0 1.5 2.5 2 2 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Glycos_transf_2 PF00535.21 EAK87979.1 - 2.1e-17 63.3 0.5 3.5e-17 62.6 0.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EAK87979.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 vWA-TerF-like PF10138.4 EAK87979.1 - 0.045 13.5 0.2 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 vWA found in TerF C terminus PUF PF00806.14 EAK87980.1 - 0.00075 18.8 0.0 0.013 14.9 0.0 3.2 2 0 0 2 2 2 1 Pumilio-family RNA binding repeat Ribosomal_L30 PF00327.15 EAK87981.1 - 0.021 14.4 0.1 0.057 13.0 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e Chibby PF14645.1 EAK87981.1 - 0.028 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Chibby family zf-RanBP PF00641.13 EAK87982.1 - 1.6 7.9 17.3 0.064 12.3 6.4 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Sdh_cyt PF01127.17 EAK87983.1 - 0.014 15.2 6.4 0.021 14.6 4.4 1.3 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Vesiculo_matrix PF06326.7 EAK87983.1 - 0.056 12.8 0.1 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Vesiculovirus matrix protein VKOR PF07884.9 EAK87983.1 - 0.87 9.4 9.0 3.2 7.6 6.3 1.8 1 1 0 1 1 1 0 Vitamin K epoxide reductase family ATP-synt_8 PF00895.15 EAK87983.1 - 1.7 8.9 3.8 2 8.7 0.1 2.2 2 0 0 2 2 2 0 ATP synthase protein 8 PIG-P PF08510.7 EAK87983.1 - 7.9 6.1 6.9 13 5.4 4.7 1.5 1 1 0 1 1 1 0 PIG-P Noggin PF05806.7 EAK87984.1 - 0.05 12.9 1.9 0.051 12.8 0.1 1.9 2 0 0 2 2 2 0 Noggin CagY_I PF14585.1 EAK87986.1 - 0.5 10.3 8.5 0.46 10.4 1.8 3.5 2 1 0 2 2 2 0 CagY type 1 repeat DUF3646 PF12362.3 EAK87987.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal SURF6 PF04935.7 EAK87988.1 - 0.00019 20.8 0.8 0.00036 19.8 0.6 1.4 1 0 0 1 1 1 1 Surfeit locus protein 6 WH2 PF02205.15 EAK87989.1 - 0.015 14.8 0.1 0.039 13.5 0.0 1.7 1 0 0 1 1 1 0 WH2 motif DUF3678 PF12435.3 EAK87989.1 - 5.4 6.6 11.3 18 4.9 7.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) S10_plectin PF03501.10 EAK87991.1 - 5.2e-39 132.0 0.2 6e-39 131.7 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain AAA PF00004.24 EAK87992.1 - 8.6e-38 129.5 0.0 1.8e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAK87992.1 - 1.7e-07 30.5 0.0 5.6e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EAK87992.1 - 7.7e-06 25.9 0.0 2.2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EAK87992.1 - 6e-05 23.1 0.4 0.00095 19.3 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EAK87992.1 - 8.3e-05 22.4 0.3 0.0092 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EAK87992.1 - 8.9e-05 21.9 0.2 0.0091 15.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EAK87992.1 - 0.00025 20.8 0.3 0.0091 15.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EAK87992.1 - 0.0003 21.5 0.0 0.0021 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EAK87992.1 - 0.0016 18.1 0.1 0.0043 16.7 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EAK87992.1 - 0.0023 17.9 0.0 0.017 15.1 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EAK87992.1 - 0.0024 18.0 0.0 0.0076 16.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 EAK87992.1 - 0.0028 17.2 0.4 0.12 11.8 0.2 2.9 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EAK87992.1 - 0.003 16.7 0.1 0.0058 15.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EAK87992.1 - 0.0037 17.5 0.2 0.041 14.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAK87992.1 - 0.0075 16.0 0.0 0.019 14.7 0.0 1.6 2 0 0 2 2 1 1 Part of AAA domain TIP49 PF06068.8 EAK87992.1 - 0.0081 14.9 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EAK87992.1 - 0.012 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EAK87992.1 - 0.025 13.6 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EAK87992.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EAK87992.1 - 0.068 12.0 0.1 4.4 6.1 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Zot PF05707.7 EAK87992.1 - 0.072 12.5 0.1 0.63 9.4 0.1 2.4 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) SKI PF01202.17 EAK87992.1 - 0.099 12.5 0.1 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase MCM PF00493.18 EAK87992.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family Chorein_N PF12624.2 EAK87994.1 - 4.2e-28 97.2 6.2 6.1e-28 96.7 1.7 3.2 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter SAP25 PF15476.1 EAK87994.1 - 5.6 6.4 3.5 12 5.3 2.4 1.5 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 MTTB PF06253.6 EAK87996.1 - 0.8 7.3 0.1 1.3 6.7 0.0 1.2 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) ArsC PF03960.10 EAK87998.1 - 0.067 13.2 6.2 0.095 12.7 0.1 3.5 2 1 1 3 3 3 0 ArsC family HAS-barrel PF09378.5 EAK87999.1 - 0.16 11.8 2.7 0.33 10.8 0.1 3.0 2 0 0 2 2 2 0 HAS barrel domain DUF948 PF06103.6 EAK87999.1 - 0.18 11.6 8.1 8.9 6.2 0.0 4.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 EAK87999.1 - 0.45 10.3 20.3 0.11 12.3 4.7 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) RNA_helicase PF00910.17 EAK88000.1 - 0.0026 17.9 0.9 0.0067 16.5 0.7 1.7 1 0 0 1 1 1 1 RNA helicase DUF1690 PF07956.6 EAK88000.1 - 3 7.8 13.9 4.4 7.2 2.7 2.2 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Clp1 PF06807.9 EAK88002.1 - 7.3e-11 42.1 0.0 2.2e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EAK88002.1 - 1.1e-10 41.4 0.0 2.1e-09 37.1 0.0 2.4 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EAK88002.1 - 1.3e-05 24.6 0.0 2.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.12 EAK88002.1 - 0.0018 17.8 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EAK88002.1 - 0.0022 17.4 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 EAK88002.1 - 0.0022 18.7 0.0 0.0055 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EAK88002.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EAK88002.1 - 0.019 14.9 0.0 0.054 13.4 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 EAK88002.1 - 0.02 15.1 0.1 0.091 13.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EAK88002.1 - 0.044 13.3 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 EAK88002.1 - 0.075 12.5 0.1 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EAK88002.1 - 0.075 13.3 0.1 0.18 12.1 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EAK88002.1 - 0.16 11.9 0.0 0.52 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_C48 PF02902.14 EAK88003.1 - 9.3e-40 136.5 2.9 1.8e-39 135.6 2.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PP2C PF00481.16 EAK88004.1 - 6.4e-11 42.1 0.1 0.00014 21.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EAK88004.1 - 1.3e-07 31.5 0.0 0.00056 19.6 0.0 2.6 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EAK88004.1 - 1.1e-06 28.1 0.0 0.0091 15.4 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Acyl-CoA_dh_M PF02770.14 EAK88004.1 - 0.17 11.4 0.0 8.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain FHA PF00498.21 EAK88006.1 - 4.4e-15 55.5 0.2 1.5e-14 53.8 0.1 1.9 1 0 0 1 1 1 1 FHA domain Sec63 PF02889.11 EAK88007.1 - 1.7e-32 112.9 0.1 3.1e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EAK88007.1 - 3.3e-27 95.0 3.4 4.9e-26 91.2 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 EAK88007.1 - 1.5e-08 34.7 0.0 1.5e-08 34.7 0.0 3.0 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EAK88007.1 - 1.3e-07 31.3 0.0 1.2e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.11 EAK88007.1 - 0.037 13.2 0.0 1.6 7.9 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 EAK88007.1 - 0.2 11.7 2.2 2.1 8.4 0.1 3.5 3 1 0 3 3 3 0 AAA domain NPV_P10 PF05531.7 EAK88010.1 - 0.01 16.0 3.9 0.013 15.6 2.7 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein RGS-like PF09128.6 EAK88010.1 - 0.02 14.3 1.6 0.024 14.1 1.1 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain CHD5 PF04420.9 EAK88010.1 - 0.074 12.7 2.2 0.091 12.4 1.5 1.2 1 0 0 1 1 1 0 CHD5-like protein Nse4_C PF08743.5 EAK88011.1 - 0.00011 22.1 0.1 0.00052 19.9 0.1 2.2 1 1 0 1 1 1 1 Nse4 C-terminal COesterase PF00135.23 EAK88013.1 - 4.8e-62 210.3 0.9 1e-61 209.2 0.6 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAK88013.1 - 7.9e-11 41.9 0.0 5.4e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAK88013.1 - 1.5e-05 24.7 0.0 2.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EAK88013.1 - 0.00016 21.1 0.0 0.00045 19.7 0.0 1.7 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF1749 PF08538.5 EAK88013.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EAK88013.1 - 0.012 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAK88013.1 - 0.046 12.9 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF948 PF06103.6 EAK88013.1 - 2.2 8.1 5.7 0.63 9.9 1.7 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Acetyltransf_1 PF00583.19 EAK88014.1 - 6.2e-10 38.9 0.0 1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EAK88014.1 - 0.00013 21.6 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EAK88014.1 - 0.0048 17.0 0.6 0.0095 16.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAK88014.1 - 0.0054 16.5 0.1 0.0097 15.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAK88014.1 - 0.09 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_5 PF07728.9 EAK88015.1 - 1.1e-84 281.1 1.0 1.8e-23 82.8 0.0 9.0 6 4 1 7 7 7 7 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EAK88015.1 - 3.4e-23 81.7 0.0 1.8e-07 30.8 0.0 6.7 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EAK88015.1 - 6e-14 52.3 0.5 0.053 13.7 0.0 5.6 4 1 0 4 4 4 4 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EAK88015.1 - 8.2e-13 48.8 1.4 0.00041 20.6 0.0 5.3 4 0 0 4 4 4 2 ABC transporter AAA_16 PF13191.1 EAK88015.1 - 8.7e-12 45.3 0.0 0.11 12.4 0.0 4.7 4 0 0 4 4 4 3 AAA ATPase domain Sigma54_activat PF00158.21 EAK88015.1 - 2.7e-11 43.2 0.3 0.06 12.8 0.0 5.5 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_17 PF13207.1 EAK88015.1 - 3.2e-11 44.1 1.1 0.14 12.9 0.0 6.7 5 0 0 5 5 5 2 AAA domain Miro PF08477.8 EAK88015.1 - 5.4e-11 43.0 0.6 0.038 14.4 0.0 5.5 5 0 0 5 5 4 2 Miro-like protein Mg_chelatase PF01078.16 EAK88015.1 - 1.7e-10 40.4 0.0 0.25 10.5 0.0 5.8 6 0 0 6 6 6 3 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EAK88015.1 - 1.7e-10 41.1 3.4 0.13 12.4 0.0 6.4 6 0 0 6 6 6 2 AAA domain T2SE PF00437.15 EAK88015.1 - 2e-10 40.0 7.5 0.0011 17.8 0.0 5.0 5 0 0 5 5 5 2 Type II/IV secretion system protein PduV-EutP PF10662.4 EAK88015.1 - 4.6e-07 29.4 1.4 0.14 11.5 0.0 4.4 4 0 0 4 4 4 2 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EAK88015.1 - 5.4e-07 29.7 0.0 1.2 9.0 0.0 4.4 4 0 0 4 4 4 1 AAA domain DUF258 PF03193.11 EAK88015.1 - 5.7e-07 28.8 1.2 0.049 12.8 0.0 4.4 4 0 0 4 4 4 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EAK88015.1 - 6.5e-07 29.3 0.0 0.28 11.0 0.0 5.1 5 0 0 5 5 5 1 AAA domain AAA_29 PF13555.1 EAK88015.1 - 1.4e-06 27.7 0.9 0.00079 18.9 0.0 4.0 4 0 0 4 4 4 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EAK88015.1 - 3.2e-06 26.4 0.0 3.6 6.6 0.0 4.5 4 0 0 4 4 4 1 Zeta toxin Sigma54_activ_2 PF14532.1 EAK88015.1 - 3.7e-06 27.0 0.0 2.1 8.3 0.0 5.1 5 0 0 5 5 5 1 Sigma-54 interaction domain DEAD PF00270.24 EAK88015.1 - 3.7e-06 26.5 0.0 0.51 9.8 0.0 4.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase AAA_19 PF13245.1 EAK88015.1 - 1e-05 25.1 0.0 12 5.7 0.0 4.3 4 0 0 4 4 4 0 Part of AAA domain AAA_18 PF13238.1 EAK88015.1 - 5.1e-05 23.5 45.7 0.0095 16.2 0.0 8.8 8 2 1 9 9 6 4 AAA domain ATP-synt_ab PF00006.20 EAK88015.1 - 0.00026 20.5 0.1 4.4 6.7 0.0 4.0 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 EAK88015.1 - 0.00028 21.2 18.1 0.00028 21.2 12.5 12.7 4 4 4 11 11 3 1 AAA domain MobB PF03205.9 EAK88015.1 - 0.0003 20.4 0.2 0.54 9.9 0.0 3.7 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EAK88015.1 - 0.00032 20.1 0.0 0.51 9.7 0.0 3.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_30 PF13604.1 EAK88015.1 - 0.00043 19.9 0.0 13 5.3 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.1 EAK88015.1 - 0.00073 18.9 0.0 1.9 7.8 0.0 4.0 4 0 0 4 4 3 1 AAA domain NACHT PF05729.7 EAK88015.1 - 0.0011 18.6 6.8 3.1 7.4 0.0 5.2 6 0 0 6 6 4 1 NACHT domain SRP54 PF00448.17 EAK88015.1 - 0.0035 16.7 1.4 0.95 8.8 0.1 3.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain RuvB_N PF05496.7 EAK88015.1 - 0.0088 15.1 0.5 2.7 6.9 0.0 4.3 4 0 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus CPT PF07931.7 EAK88015.1 - 0.022 14.4 0.0 11 5.6 0.0 4.0 4 1 0 4 4 4 0 Chloramphenicol phosphotransferase-like protein FtsK_SpoIIIE PF01580.13 EAK88015.1 - 0.06 12.8 0.3 0.99 8.8 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family Phe_ZIP PF08916.6 EAK88015.1 - 0.099 12.9 0.6 1.4 9.2 0.0 3.0 3 0 0 3 3 2 0 Phenylalanine zipper SMN PF06003.7 EAK88015.1 - 0.29 10.2 1.4 0.61 9.1 1.0 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) HVSL PF09749.4 EAK88016.1 - 1.1e-06 27.8 0.1 0.00057 18.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised conserved protein EF-hand_1 PF00036.27 EAK88017.1 - 3.4e-06 25.9 8.7 0.0092 15.2 1.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EAK88017.1 - 2.1e-05 24.5 5.9 0.084 13.0 0.2 3.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EAK88017.1 - 0.001 18.6 5.7 0.12 11.9 0.5 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EAK88017.1 - 0.0022 17.7 7.4 0.75 9.8 0.6 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EAK88017.1 - 0.037 13.3 7.7 0.012 14.8 1.3 2.6 2 0 0 2 2 2 0 EF hand RNA_pol_Rpa2_4 PF06883.7 EAK88017.1 - 0.098 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase I, Rpa2 specific domain Glycos_transf_1 PF00534.15 EAK88018.1 - 2e-38 131.5 0.0 3.7e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EAK88018.1 - 3.3e-18 66.3 0.0 1.2e-17 64.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EAK88018.1 - 4.9e-16 59.1 0.0 9.6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EAK88018.1 - 2.2e-15 56.8 0.0 7.5e-15 55.0 0.0 1.8 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.1 EAK88018.1 - 3.4e-09 36.6 0.1 0.00088 19.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Alpha-amylase PF00128.19 EAK88018.1 - 6.8e-07 28.9 0.0 2.8e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_trans_1_2 PF13524.1 EAK88018.1 - 0.017 15.4 0.0 0.05 13.8 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 Pkinase PF00069.20 EAK88019.1 - 6e-18 64.9 0.0 1.4e-10 40.8 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAK88019.1 - 1.5e-11 43.8 0.0 7.6e-08 31.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAK88019.1 - 0.0072 15.3 0.0 0.075 11.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like SAM_2 PF07647.12 EAK88020.1 - 0.0063 16.3 0.1 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EAK88020.1 - 0.035 14.2 0.2 0.071 13.3 0.1 1.6 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) USP7_ICP0_bdg PF12436.3 EAK88020.1 - 0.11 11.7 1.7 0.24 10.5 0.2 1.9 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 AMP-binding PF00501.23 EAK88021.1 - 2.9e-70 236.7 0.0 3.7e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2592 PF10766.4 EAK88022.1 - 0.21 10.9 0.2 0.64 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2592) Proteasome PF00227.21 EAK88023.1 - 1.4e-25 89.6 0.4 5.2e-21 74.7 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit CENP-P PF13096.1 EAK88023.1 - 0.065 12.5 0.1 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Glyco_transf_8 PF01501.15 EAK88025.1 - 4.8e-09 35.9 0.7 5.2e-09 35.7 0.5 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 P53_tetramer PF07710.6 EAK88025.1 - 0.053 12.6 0.9 1.8 7.6 0.1 2.4 2 0 0 2 2 2 0 P53 tetramerisation motif OppC_N PF12911.2 EAK88025.1 - 0.69 9.3 2.5 0.86 9.0 0.8 1.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF1168 PF06658.7 EAK88026.1 - 2e-19 69.5 22.7 2.5e-19 69.1 15.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Transglut_prok PF09017.5 EAK88026.1 - 0.13 11.3 2.2 0.14 11.2 1.5 1.1 1 0 0 1 1 1 0 Microbial transglutaminase DUF789 PF05623.7 EAK88026.1 - 1.2 8.5 8.1 1.3 8.3 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Herpes_DNAp_acc PF04929.7 EAK88026.1 - 3.8 6.3 10.5 4.3 6.2 7.3 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TFIIS_M PF07500.9 EAK88027.1 - 7.1e-21 74.4 1.2 7.1e-21 74.4 0.8 2.0 1 1 1 2 2 2 1 Transcription factor S-II (TFIIS), central domain zf-HC5HC2H_2 PF13832.1 EAK88028.1 - 5.5e-25 87.5 21.6 6.3e-09 35.8 0.6 6.0 5 1 0 5 5 5 4 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EAK88028.1 - 1.4e-10 41.1 7.1 2.3e-06 27.6 0.6 6.4 6 1 1 7 7 7 2 PHD-like zinc-binding domain PHD PF00628.24 EAK88028.1 - 5.5e-10 38.7 45.0 1.1e-05 25.0 2.4 5.0 4 0 0 4 4 4 4 PHD-finger PHD_2 PF13831.1 EAK88028.1 - 1.6e-09 36.9 27.7 1.2e-06 27.7 1.5 3.7 3 0 0 3 3 3 2 PHD-finger DER1 PF04511.10 EAK88030.1 - 7.5e-44 149.6 16.8 8.5e-44 149.4 11.6 1.0 1 0 0 1 1 1 1 Der1-like family Kazal_1 PF00050.16 EAK88032.1 - 1.2e-06 28.4 6.9 0.0093 15.9 0.1 2.6 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EAK88032.1 - 0.00011 21.9 9.5 0.022 14.7 2.4 2.7 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kdo_hydroxy PF11004.3 EAK88032.1 - 0.13 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase TPT PF03151.11 EAK88034.1 - 2.4e-19 69.4 13.3 2.4e-19 69.4 9.3 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EAK88034.1 - 8.4e-13 47.8 19.5 8.4e-13 47.8 13.5 2.0 1 1 0 2 2 2 1 UAA transporter family EamA PF00892.15 EAK88034.1 - 1.3e-06 28.4 33.2 1.9e-05 24.6 9.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EAK88034.1 - 0.00017 21.7 21.2 0.022 14.9 1.1 3.2 2 1 0 2 2 2 2 Multidrug resistance efflux transporter Notch PF00066.12 EAK88035.1 - 1.2e-38 131.0 201.6 9.6e-13 48.1 11.2 12.7 13 0 0 13 13 13 6 LNR domain TSP_1 PF00090.14 EAK88035.1 - 9.7e-37 124.8 98.5 4.3e-10 39.5 2.9 19.5 21 2 1 22 22 22 11 Thrombospondin type 1 domain DUF1461 PF07314.6 EAK88035.1 - 2.9 7.5 0.3 5.6 6.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Cons_hypoth698 PF03601.9 EAK88035.1 - 5.9 5.4 1.2 9.5 4.7 0.8 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 698 DnaJ PF00226.26 EAK88036.1 - 3.9e-25 87.3 1.9 8.4e-25 86.3 1.3 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 EAK88036.1 - 1.1e-20 73.7 0.2 1.1e-20 73.7 0.1 2.0 2 1 1 3 3 3 1 Domain of unknown function (DUF1977) Cytochrom_B_N PF00033.14 EAK88036.1 - 0.083 12.2 0.1 0.19 11.0 0.1 1.6 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB YfdX PF10938.3 EAK88036.1 - 0.25 10.9 1.9 0.42 10.2 0.0 2.2 3 0 0 3 3 3 0 YfdX protein NAC PF01849.13 EAK88038.1 - 6.5e-18 64.0 0.0 1.4e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 EAK88038.1 - 1.7e-05 24.4 0.1 3.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 EAK88038.1 - 0.0016 17.8 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain 5_nucleotid_C PF02872.13 EAK88039.1 - 2.1e-31 109.0 0.0 5.8e-31 107.5 0.0 1.8 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EAK88039.1 - 5.8e-06 25.8 0.7 1.6e-05 24.3 0.5 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAK88039.1 - 0.0032 17.3 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DTW PF03942.10 EAK88040.1 - 1.9e-19 69.6 0.0 2.8e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 DTW domain 4HBT PF03061.17 EAK88041.1 - 1.8e-06 28.0 0.0 2.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily BPL_N PF09825.4 EAK88042.1 - 3e-09 36.1 0.0 3.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal SecD-TM1 PF13721.1 EAK88043.1 - 1.6 9.0 5.8 17 5.7 0.2 3.2 4 0 0 4 4 4 0 SecD export protein N-terminal TM region DnaJ PF00226.26 EAK88044.1 - 9.3e-10 38.0 0.0 1.1e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EAK88044.1 - 9.9e-06 25.3 0.0 9.9e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Pam16 GLTP PF08718.6 EAK88045.1 - 4.7e-28 98.1 0.0 1.5e-27 96.4 0.0 1.7 1 1 1 2 2 2 1 Glycolipid transfer protein (GLTP) SbmA_BacA PF05992.7 EAK88047.1 - 1.1e-61 208.8 11.0 1.2e-61 208.6 7.6 1.0 1 0 0 1 1 1 1 SbmA/BacA-like family SbmA_BacA PF05992.7 EAK88048.1 - 2.3e-57 194.6 14.7 2.6e-57 194.4 10.2 1.0 1 0 0 1 1 1 1 SbmA/BacA-like family ABC_membrane_2 PF06472.10 EAK88048.1 - 1.7e-13 50.3 7.7 5.9e-13 48.5 5.4 1.9 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 Gpi1 PF05024.10 EAK88050.1 - 5.5e-32 110.9 21.6 5.5e-32 110.9 14.9 2.8 3 0 0 3 3 3 1 N-acetylglucosaminyl transferase component (Gpi1) RRM_1 PF00076.17 EAK88051.1 - 1.6e-31 107.7 0.2 4.3e-15 55.1 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK88051.1 - 4.4e-29 100.2 0.0 3.6e-14 52.4 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK88051.1 - 2.1e-14 53.1 0.0 1.9e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Endonuclease_NS PF01223.18 EAK88052.1 - 6.3e-36 123.9 0.0 1.1e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease YfcL PF08891.6 EAK88052.1 - 0.074 13.0 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 YfcL protein HALZ PF02183.13 EAK88053.1 - 0.35 10.6 5.4 0.72 9.6 3.7 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4201 PF13870.1 EAK88054.1 - 0.038 13.4 2.8 0.075 12.4 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) WASH-7_N PF14745.1 EAK88054.1 - 0.072 11.2 0.2 0.11 10.6 0.1 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal HD_4 PF13328.1 EAK88054.1 - 0.11 12.1 0.1 1.9 8.1 0.0 2.0 2 0 0 2 2 2 0 HD domain Zip PF02535.17 EAK88055.1 - 7.1e-37 127.1 11.7 9.4e-37 126.6 8.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Viral_NABP PF05515.6 EAK88056.1 - 0.0056 16.9 1.2 0.017 15.4 0.8 1.8 1 0 0 1 1 1 1 Viral nucleic acid binding Chromo PF00385.19 EAK88057.1 - 1.6e-10 40.5 1.0 4e-10 39.2 0.7 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RCC1_2 PF13540.1 EAK88057.1 - 0.13 11.9 0.6 15 5.3 0.0 3.2 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat RWD PF05773.17 EAK88058.1 - 1.1e-11 44.6 3.5 2.2e-11 43.6 2.4 1.6 1 1 0 1 1 1 1 RWD domain Elf1 PF05129.8 EAK88059.1 - 2.4e-26 91.2 4.3 4.5e-26 90.3 3.0 1.5 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 EAK88059.1 - 0.0027 17.9 0.4 0.0065 16.7 0.2 1.7 1 0 0 1 1 1 1 Restriction alleviation protein Lar FdhE PF04216.7 EAK88059.1 - 0.019 14.6 0.1 0.035 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Rubredoxin PF00301.15 EAK88059.1 - 0.061 13.2 0.7 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Rubredoxin FCH PF00611.18 EAK88060.1 - 4.8e-12 45.9 3.7 4.9e-11 42.6 0.2 3.6 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Nipped-B_C PF12830.2 EAK88061.1 - 1.8e-08 34.2 2.3 1.8e-08 34.2 1.6 4.3 4 1 0 4 4 4 2 Sister chromatid cohesion C-terminus PHD PF00628.24 EAK88061.1 - 5.8e-05 22.6 6.9 5.8e-05 22.6 4.8 2.9 3 0 0 3 3 3 1 PHD-finger HEAT PF02985.17 EAK88061.1 - 0.076 13.1 0.8 6.7 7.0 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat PHD_2 PF13831.1 EAK88061.1 - 0.84 9.0 9.3 0.034 13.4 1.7 2.2 2 0 0 2 2 2 0 PHD-finger DEAD PF00270.24 EAK88062.1 - 9e-20 70.8 0.0 2.7e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK88062.1 - 1.5e-06 27.9 0.1 3.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2790 PF10976.3 EAK88062.1 - 0.037 13.8 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) SSP160 PF06933.6 EAK88063.1 - 0.051 11.5 7.6 0.076 10.9 5.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FHA PF00498.21 EAK88064.1 - 3e-17 62.4 0.8 8.9e-17 60.9 0.5 1.9 1 0 0 1 1 1 1 FHA domain Nup54 PF13874.1 EAK88064.1 - 0.0014 18.3 11.9 0.0014 18.3 8.3 3.1 2 1 1 3 3 3 1 Nucleoporin complex subunit 54 Reo_sigmaC PF04582.7 EAK88064.1 - 0.16 11.1 12.3 0.14 11.3 3.0 2.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein PITH PF06201.8 EAK88065.1 - 5.6e-34 117.0 2.4 7.4e-34 116.7 1.7 1.1 1 0 0 1 1 1 1 PITH domain CAP PF00188.21 EAK88066.1 - 9.2e-21 74.6 2.8 1.9e-20 73.6 1.9 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RIO1 PF01163.17 EAK88067.1 - 1.8e-54 183.9 0.3 6.3e-29 100.6 0.0 2.6 1 1 1 2 2 2 2 RIO1 family FERM_C PF09380.5 EAK88069.1 - 0.12 12.5 0.1 0.24 11.6 0.0 1.6 1 1 0 1 1 1 0 FERM C-terminal PH-like domain Abi PF02517.11 EAK88071.1 - 2.6e-11 43.4 1.6 2.6e-11 43.4 1.1 2.3 2 0 0 2 2 2 1 CAAX protease self-immunity EF-hand_1 PF00036.27 EAK88073.1 - 0.0017 17.5 5.5 0.003 16.7 1.1 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EAK88073.1 - 0.031 14.1 4.3 0.043 13.7 1.1 2.8 2 1 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 EAK88073.1 - 0.12 12.5 10.1 0.096 12.8 3.8 3.0 2 1 0 3 3 3 0 EF-hand domain pair Trichoplein PF13868.1 EAK88073.1 - 0.47 8.7 29.4 0.67 8.2 20.3 1.2 1 0 0 1 1 1 0 Tumour suppressor, Mitostatin V_ATPase_I PF01496.14 EAK88073.1 - 0.74 7.6 15.1 1.1 6.9 10.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pox_A_type_inc PF04508.7 EAK88073.1 - 0.81 9.6 6.7 4.1 7.4 2.4 3.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF1843 PF08898.5 EAK88073.1 - 4.5 7.3 10.8 5.1 7.2 0.7 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) COG2 PF06148.6 EAK88074.1 - 0.0042 16.9 3.6 0.37 10.6 0.2 3.1 2 2 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 THP2 PF09432.5 EAK88074.1 - 0.0058 16.4 0.3 0.25 11.1 0.0 2.6 1 1 1 2 2 2 1 Tho complex subunit THP2 TBPIP PF07106.8 EAK88074.1 - 0.011 15.3 7.2 0.064 12.8 0.7 2.9 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Helicase_Sgs1 PF11408.3 EAK88074.1 - 0.051 13.4 0.0 5.1 6.9 0.0 2.5 1 1 0 2 2 2 0 Sgs1 RecQ helicase GLE1 PF07817.8 EAK88074.1 - 0.14 11.0 3.8 0.73 8.7 0.4 2.4 2 1 0 2 2 2 0 GLE1-like protein IncA PF04156.9 EAK88074.1 - 0.16 11.5 3.3 0.59 9.6 0.8 2.2 2 0 0 2 2 2 0 IncA protein Nucleoporin_FG PF13634.1 EAK88074.1 - 0.19 11.9 25.6 2.6 8.3 17.8 2.1 1 1 0 1 1 1 0 Nucleoporin FG repeat region NYD-SP28 PF14772.1 EAK88074.1 - 0.34 11.0 3.4 4.4 7.4 0.1 2.7 2 1 1 3 3 3 0 Sperm tail Laminin_II PF06009.7 EAK88074.1 - 0.66 9.7 5.0 5.7 6.7 0.6 2.9 2 1 1 3 3 3 0 Laminin Domain II Mod_r PF07200.8 EAK88074.1 - 0.76 9.6 3.8 7.9 6.3 0.2 2.9 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein PRANC PF09372.5 EAK88074.1 - 4 7.4 8.1 1.4 8.9 2.1 2.5 1 1 2 3 3 3 0 PRANC domain Las1 PF04031.8 EAK88075.1 - 2.7e-49 166.7 0.7 7e-49 165.4 0.0 2.1 3 0 0 3 3 3 1 Las1-like LETM1 PF07766.8 EAK88076.1 - 1.3e-40 139.1 7.0 1.8e-40 138.7 4.9 1.0 1 0 0 1 1 1 1 LETM1-like protein NUC153 PF08159.7 EAK88077.1 - 1.2e-09 37.5 8.5 7.4e-06 25.4 0.1 3.4 3 0 0 3 3 3 2 NUC153 domain RdgC PF04381.7 EAK88078.1 - 0.045 12.7 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease, RdgC HSP20 PF00011.16 EAK88078.1 - 7.7 6.4 6.7 1.8 8.4 0.1 2.9 4 0 0 4 4 4 0 Hsp20/alpha crystallin family SNARE PF05739.14 EAK88079.1 - 3.9e-12 45.6 10.5 7.8e-10 38.3 2.4 2.4 2 1 0 2 2 2 2 SNARE domain Sec20 PF03908.8 EAK88079.1 - 0.015 14.9 4.7 0.017 14.8 0.8 2.2 2 0 0 2 2 2 0 Sec20 NPV_P10 PF05531.7 EAK88079.1 - 0.021 15.0 7.9 0.097 12.9 1.5 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Uds1 PF15456.1 EAK88079.1 - 0.05 13.5 3.6 0.067 13.1 1.1 2.1 2 0 0 2 2 2 0 Up-regulated During Septation V-SNARE_C PF12352.3 EAK88079.1 - 0.19 11.7 4.5 7.1 6.7 0.3 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Sin3_corepress PF08295.7 EAK88079.1 - 0.29 10.8 5.3 0.11 12.2 1.1 2.1 2 1 1 3 3 3 0 Sin3 family co-repressor PspA_IM30 PF04012.7 EAK88079.1 - 0.3 10.4 9.7 0.14 11.4 4.9 1.6 2 0 0 2 2 2 0 PspA/IM30 family TBCA PF02970.11 EAK88079.1 - 1.8 8.6 9.9 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Tubulin binding cofactor A DUF1664 PF07889.7 EAK88079.1 - 2.9 7.6 8.0 14 5.4 1.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3847 PF12958.2 EAK88079.1 - 7.1 6.4 10.6 0.57 9.9 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3847) DsbC_N PF10411.4 EAK88080.1 - 0.097 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus Gar1 PF04410.9 EAK88081.1 - 2.7e-41 140.6 0.2 3.5e-41 140.2 0.1 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Ras PF00071.17 EAK88082.1 - 8e-05 22.0 0.2 0.00012 21.4 0.0 1.3 2 0 0 2 2 2 1 Ras family Peptidase_C57 PF03290.8 EAK88082.1 - 0.00059 18.4 0.6 0.00074 18.1 0.4 1.1 1 0 0 1 1 1 1 Vaccinia virus I7 processing peptidase Miro PF08477.8 EAK88082.1 - 0.015 15.8 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein DUF2556 PF10831.3 EAK88083.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) ASFV_360 PF01671.11 EAK88083.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 African swine fever virus multigene family 360 protein Nol1_Nop2_Fmu PF01189.12 EAK88084.1 - 1.8e-10 40.6 0.0 3.9e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EAK88084.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase PRP3 PF08572.5 EAK88085.1 - 5.7e-46 156.6 8.0 1.4e-45 155.4 5.6 1.6 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EAK88085.1 - 3.5e-30 104.2 0.1 3.5e-30 104.2 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) CTP_synth_N PF06418.9 EAK88086.1 - 1.3e-110 368.8 0.2 2e-110 368.2 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EAK88086.1 - 1.7e-40 138.5 0.0 5.1e-40 136.9 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EAK88086.1 - 0.00022 20.7 0.1 0.45 9.9 0.0 3.2 3 0 0 3 3 3 2 Peptidase C26 CbiA PF01656.18 EAK88086.1 - 0.0051 16.2 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EAK88086.1 - 0.12 11.0 0.1 0.22 10.2 0.1 1.3 1 0 0 1 1 1 0 ArgK protein CactinC_cactus PF09732.4 EAK88087.1 - 1.3e-41 141.1 5.8 2.7e-41 140.0 4.0 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 EAK88087.1 - 2.4e-06 26.9 1.7 0.0021 17.3 0.0 2.4 2 0 0 2 2 2 2 Conserved mid region of cactin U3_assoc_6 PF08640.6 EAK88087.1 - 0.00016 21.3 2.6 0.00016 21.3 1.8 2.7 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 CLASP_N PF12348.3 EAK88088.1 - 1.2e-05 24.8 5.7 1.2e-05 24.8 4.0 3.0 3 0 0 3 3 3 2 CLASP N terminal DUF2457 PF10446.4 EAK88090.1 - 0.058 12.1 21.4 0.077 11.7 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 EAK88090.1 - 0.11 11.7 19.1 0.18 11.0 13.2 1.3 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.6 EAK88090.1 - 0.14 9.9 12.1 0.2 9.5 8.1 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.8 EAK88090.1 - 4.7 4.8 20.1 7.4 4.2 14.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Big_1 PF02369.11 EAK88090.1 - 4.9 7.1 6.6 1.6 8.6 0.9 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) RRN3 PF05327.6 EAK88090.1 - 5.5 4.9 11.7 7.4 4.5 8.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Herpes_LMP1 PF05297.6 EAK88090.1 - 9.4 5.0 10.6 14 4.5 7.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Yip1 PF04893.12 EAK88093.1 - 1.3e-05 24.8 15.9 3e-05 23.5 11.0 1.7 1 1 0 1 1 1 1 Yip1 domain PgaD PF13994.1 EAK88093.1 - 4.3 6.8 7.1 0.81 9.1 2.2 1.8 2 0 0 2 2 2 0 PgaD-like protein LEDGF PF11467.3 EAK88094.1 - 0.021 14.4 0.5 0.095 12.4 0.1 2.0 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) DUF3364 PF11844.3 EAK88095.1 - 0.28 11.2 0.1 0.28 11.2 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3364) LcrG PF07216.7 EAK88098.1 - 0.11 12.5 1.3 0.35 10.9 0.9 1.8 1 0 0 1 1 1 0 LcrG protein DUF2693 PF10902.3 EAK88098.1 - 1.7 8.5 6.6 1.1 9.1 0.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2693) Peptidase_M50B PF13398.1 EAK88099.1 - 0.66 9.3 8.2 0.76 9.1 5.7 1.1 1 0 0 1 1 1 0 Peptidase M50B-like AA_permease_2 PF13520.1 EAK88099.1 - 2 6.8 14.3 2.7 6.4 9.9 1.0 1 0 0 1 1 1 0 Amino acid permease G3P_acyltransf PF02660.10 EAK88099.1 - 5.1 6.6 9.4 6.5 6.2 6.5 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase DUF4521 PF15021.1 EAK88103.1 - 0.11 12.0 1.9 0.18 11.3 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) DUF948 PF06103.6 EAK88104.1 - 0.27 11.1 2.6 1.8 8.4 0.4 3.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tcf25 PF04910.9 EAK88107.1 - 3.2e-78 263.2 9.9 5.3e-78 262.4 6.9 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PRELI PF04707.9 EAK88109.1 - 5.4e-26 91.0 0.5 5.4e-26 91.0 0.4 1.4 2 0 0 2 2 2 1 PRELI-like family RE_HindIII PF09518.5 EAK88111.1 - 0.0064 15.4 0.9 0.013 14.4 0.6 1.4 1 0 0 1 1 1 1 HindIII restriction endonuclease zf-CCCH PF00642.19 EAK88111.1 - 1.4 8.7 23.4 0.11 12.1 0.8 4.4 4 1 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3883 PF13020.1 EAK88113.1 - 5.3e-22 77.3 0.1 6.6e-22 77.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) DUF4420 PF14390.1 EAK88113.1 - 0.054 12.3 0.0 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4420) DUF547 PF04784.9 EAK88113.1 - 0.084 12.7 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF547 RRM_1 PF00076.17 EAK88114.1 - 2.9e-17 62.0 0.0 4.6e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK88114.1 - 2e-14 53.3 0.0 2.8e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK88114.1 - 3e-10 39.7 0.0 4.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CS PF04969.11 EAK88115.1 - 2.5e-08 34.3 0.0 7.2e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EAK88116.1 - 1.9e-10 40.2 15.2 0.0021 17.6 0.0 6.3 6 1 1 7 7 7 5 TPR repeat TPR_6 PF13174.1 EAK88116.1 - 7.2e-09 35.5 0.7 20 5.9 0.0 8.7 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAK88116.1 - 5.8e-08 31.9 7.0 0.88 9.5 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAK88116.1 - 8.3e-07 28.4 16.0 0.8 9.7 0.0 8.5 11 0 0 11 11 10 2 Tetratricopeptide repeat Apc3 PF12895.2 EAK88116.1 - 8.9e-07 28.9 14.1 0.001 19.1 0.1 5.4 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EAK88116.1 - 2.7e-06 27.2 6.0 4.6 7.2 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAK88116.1 - 4.3e-06 26.9 1.6 2.1 8.7 0.1 5.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAK88116.1 - 6.9e-06 26.5 0.1 0.93 10.2 0.0 4.7 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAK88116.1 - 1.5e-05 24.4 26.4 0.39 10.5 0.0 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EAK88116.1 - 0.0001 22.0 0.1 0.12 12.2 0.0 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAK88116.1 - 0.00072 19.0 20.9 0.45 10.2 0.7 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat RPN7 PF10602.4 EAK88116.1 - 0.0047 16.3 14.4 0.2 11.0 0.6 4.8 4 1 0 5 5 5 1 26S proteasome subunit RPN7 TPR_14 PF13428.1 EAK88116.1 - 0.037 14.6 0.0 60 4.6 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EAK88116.1 - 0.042 14.0 0.1 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Guanylate_cyc PF00211.15 EAK88117.1 - 3.8e-29 101.3 0.0 6.3e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Topoisom_I_N PF02919.10 EAK88118.1 - 0.57 9.4 7.4 2.1 7.6 0.7 2.9 1 1 1 3 3 3 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Sec62 PF03839.11 EAK88119.1 - 1.5e-24 86.7 3.0 2e-24 86.2 2.1 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 Dymeclin PF09742.4 EAK88120.1 - 1.5e-139 466.2 36.7 1.8e-139 465.9 25.5 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF663 PF04950.7 EAK88121.1 - 5.6e-68 229.0 1.3 5.6e-68 229.0 0.9 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EAK88121.1 - 2e-21 75.3 0.0 4.6e-21 74.1 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain RNA_pol_Rpc4 PF05132.9 EAK88122.1 - 5.4e-05 23.1 0.1 0.0037 17.2 0.0 2.9 1 1 1 2 2 2 2 RNA polymerase III RPC4 zf-B_box PF00643.19 EAK88125.1 - 6.6e-08 32.3 35.1 1.9e-07 30.8 6.8 3.2 4 0 0 4 4 4 2 B-box zinc finger ECH_C PF13766.1 EAK88125.1 - 0.024 14.7 0.5 0.072 13.2 0.3 1.8 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region DUF3645 PF12359.3 EAK88125.1 - 0.087 11.9 1.3 3.1 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) zf-C3HC4_3 PF13920.1 EAK88125.1 - 0.23 11.1 37.8 0.079 12.6 6.1 4.3 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) NusB PF01029.13 EAK88125.1 - 0.74 9.8 4.2 18 5.3 0.0 2.6 2 0 0 2 2 2 0 NusB family SUKH_6 PF14568.1 EAK88125.1 - 1.3 9.5 15.9 0.027 14.9 2.0 3.6 3 1 1 4 4 4 0 SMI1-KNR4 cell-wall zf-C3HC4_2 PF13923.1 EAK88125.1 - 2.8 8.0 37.7 0.17 11.9 2.0 4.7 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK88125.1 - 3.5 7.4 38.7 0.027 14.1 2.6 3.7 3 0 0 3 3 3 0 zinc-RING finger domain BTB PF00651.26 EAK88126.1 - 1e-13 51.1 0.0 2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain CENP-F_C_Rb_bdg PF10490.4 EAK88126.1 - 0.037 13.3 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Med26 PF08711.6 EAK88127.1 - 1.5e-11 43.6 5.1 1.7e-10 40.2 2.1 2.7 2 0 0 2 2 2 2 TFIIS helical bundle-like domain Epimerase PF01370.16 EAK88128.1 - 1.4e-27 96.6 0.0 3.6e-27 95.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAK88128.1 - 4.8e-22 77.9 0.1 6.8e-22 77.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EAK88128.1 - 2.1e-21 75.9 0.0 9.2e-21 73.8 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EAK88128.1 - 2.1e-17 63.7 0.0 2.8e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAK88128.1 - 2.2e-09 36.9 0.0 4.2e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EAK88128.1 - 4.6e-07 29.0 0.0 7.3e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EAK88128.1 - 7e-06 25.8 0.0 1.4e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EAK88128.1 - 7.7e-05 22.6 0.0 0.00028 20.8 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EAK88128.1 - 0.0031 16.4 0.0 0.0038 16.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 EAK88128.1 - 0.052 12.5 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Myb_DNA-bind_6 PF13921.1 EAK88129.1 - 0.026 14.6 0.1 0.11 12.5 0.0 2.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain SSXT PF05030.7 EAK88130.1 - 0.0032 16.9 0.4 0.0073 15.8 0.3 1.6 1 0 0 1 1 1 1 SSXT protein (N-terminal region) zf-C2H2 PF00096.21 EAK88130.1 - 0.0066 16.7 3.9 0.023 15.0 2.7 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type PyrI_C PF02748.10 EAK88130.1 - 0.073 12.5 4.2 0.77 9.2 0.2 2.8 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_4 PF13894.1 EAK88130.1 - 0.38 11.1 5.7 0.21 11.9 2.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAK88130.1 - 2 8.6 6.9 0.32 11.2 1.7 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-CCCH PF00642.19 EAK88132.1 - 2.5e-06 27.0 17.8 9.4e-06 25.1 1.2 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EAK88132.1 - 0.0054 16.6 2.3 0.0054 16.6 1.6 3.7 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type zf-C3H1 PF10650.4 EAK88132.1 - 0.011 15.1 11.9 0.14 11.6 0.3 3.4 3 0 0 3 3 3 0 Putative zinc-finger domain Baculo_PEP_C PF04513.7 EAK88133.1 - 0.04 13.7 3.0 0.087 12.6 2.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Carbpep_Y_N PF05388.6 EAK88133.1 - 0.056 13.6 5.0 0.37 10.9 0.3 3.1 3 0 0 3 3 3 0 Carboxypeptidase Y pro-peptide VPR PF00522.13 EAK88134.1 - 0.03 14.1 2.3 2.7 7.8 0.1 2.6 2 1 0 2 2 2 0 VPR/VPX protein DUF4404 PF14357.1 EAK88134.1 - 3.5 8.1 13.1 1.2 9.5 1.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) ArfGap PF01412.13 EAK88135.1 - 4.2e-31 107.1 0.1 6.6e-31 106.5 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-RanBP PF00641.13 EAK88135.1 - 5 6.3 6.1 0.45 9.6 0.5 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF1841 PF08897.6 EAK88136.1 - 0.02 14.7 0.5 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) Mg_trans_NIPA PF05653.9 EAK88138.1 - 3.3e-20 72.2 19.8 1.3e-13 50.6 3.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA SieB PF14163.1 EAK88138.1 - 0.0024 17.4 6.1 0.032 13.8 0.0 3.6 4 0 0 4 4 4 2 Superinfection exclusion protein B DUF4097 PF13349.1 EAK88138.1 - 0.45 10.0 4.4 1.2 8.7 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4097) B-block_TFIIIC PF04182.7 EAK88140.1 - 1.1e-23 82.8 5.2 1.2e-19 69.8 0.0 3.8 3 1 0 3 3 3 2 B-block binding subunit of TFIIIC ACI44 PF15270.1 EAK88140.1 - 0.022 14.7 0.6 0.12 12.4 0.1 2.5 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor zf-C2H2_4 PF13894.1 EAK88140.1 - 0.72 10.3 3.7 3.1 8.3 2.5 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger TLD PF07534.11 EAK88142.1 - 1.4e-30 106.1 3.8 7.6e-15 55.1 0.2 2.1 1 1 1 2 2 2 2 TLD PCI PF01399.22 EAK88143.1 - 2.6e-09 37.3 0.2 9.3e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 PCI domain Histone PF00125.19 EAK88144.1 - 5.2e-20 71.3 0.0 6.5e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAK88144.1 - 0.00013 21.8 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PRP1_N PF06424.7 EAK88146.1 - 2.6e-36 124.8 3.6 4.9e-36 123.9 0.6 2.4 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EAK88146.1 - 3.8e-16 58.1 0.0 3.2 8.6 0.0 10.8 7 4 5 12 12 11 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAK88146.1 - 5.4e-12 45.8 0.0 0.28 11.5 0.0 7.5 6 2 3 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAK88146.1 - 4.2e-10 39.1 7.5 0.088 12.4 0.0 6.7 5 2 2 7 7 7 3 TPR repeat Suf PF05843.9 EAK88146.1 - 4e-07 30.0 10.5 5.4e-05 23.0 0.8 3.9 4 1 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_2 PF07719.12 EAK88146.1 - 1.4e-06 27.7 0.5 0.28 11.2 0.0 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.1 EAK88146.1 - 1.5e-06 27.5 1.6 0.014 14.5 0.1 4.9 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAK88146.1 - 0.00012 22.6 0.0 2.6 8.8 0.0 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAK88146.1 - 0.00039 20.3 4.4 34 4.9 0.0 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EAK88146.1 - 0.0023 17.1 0.1 0.51 9.4 0.0 3.2 2 1 1 3 3 3 1 Coatomer epsilon subunit TPR_12 PF13424.1 EAK88146.1 - 0.0029 17.4 1.0 0.3 11.0 0.0 4.4 5 1 2 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAK88146.1 - 0.0083 15.6 1.5 5.8 6.7 0.0 4.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAK88146.1 - 0.49 10.2 5.0 3.2 7.7 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat ATP-synt_F PF01990.12 EAK88148.1 - 1.7e-28 98.8 0.3 2.1e-28 98.5 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit VCBS PF13517.1 EAK88150.1 - 6e-20 71.3 17.4 2.2e-06 27.9 0.4 6.6 5 1 0 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EAK88150.1 - 1.5e-19 69.0 5.7 0.0056 16.3 0.0 7.3 7 0 0 7 7 7 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 EAK88150.1 - 0.00024 20.6 2.4 3 7.2 0.1 5.4 5 1 2 7 7 7 2 Insecticide toxin TcdB middle/N-terminal region LRR_4 PF12799.2 EAK88151.1 - 5.2e-12 45.0 23.7 0.0004 19.9 6.4 5.0 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAK88151.1 - 6.4e-06 25.8 24.9 1.2e-05 24.9 8.6 4.2 1 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EAK88151.1 - 0.0001 21.8 27.5 0.19 11.8 0.4 7.6 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.1 EAK88151.1 - 0.0085 16.0 23.0 2 8.7 0.7 6.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 EAK88151.1 - 1.8 9.1 19.9 20 5.9 0.3 6.6 5 0 0 5 5 5 0 Leucine rich repeat DUF155 PF02582.9 EAK88152.1 - 9e-50 168.9 1.6 9e-50 168.9 1.1 1.8 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Glyco_transf_92 PF01697.22 EAK88153.1 - 2.4e-22 79.5 5.7 5.2e-22 78.4 4.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EAK88153.1 - 2e-05 24.7 0.0 5.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 WD40 PF00400.27 EAK88156.1 - 8.3e-30 101.5 16.7 6e-10 38.6 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EAK88156.1 - 1e-23 83.0 0.3 2.6e-23 81.7 0.2 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EAK88156.1 - 0.00092 18.9 11.8 1.8 8.2 0.1 4.8 2 2 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A Choline_kinase PF01633.15 EAK88157.1 - 4.1e-42 144.1 2.2 4.1e-42 144.1 1.5 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EAK88157.1 - 0.0033 17.1 0.0 0.0051 16.5 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family HHH_4 PF14490.1 EAK88157.1 - 0.028 14.1 0.7 0.059 13.1 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain Cobalamin_bind PF01122.14 EAK88157.1 - 0.042 12.4 0.7 0.68 8.4 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic cobalamin-binding protein Thioredoxin PF00085.15 EAK88158.1 - 1.7e-14 53.3 0.1 2.6e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EAK88158.1 - 0.0031 17.5 1.5 0.0044 17.1 0.3 1.8 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EAK88158.1 - 0.0054 16.7 0.1 0.0086 16.0 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EAK88158.1 - 0.0088 15.8 0.0 0.025 14.3 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin domain DUF544 PF04424.8 EAK88158.1 - 0.017 14.9 0.2 0.032 14.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF544) TIP49 PF06068.8 EAK88159.1 - 6.4e-173 575.0 5.5 6.4e-173 575.0 3.8 1.4 1 1 1 2 2 2 1 TIP49 C-terminus AAA PF00004.24 EAK88159.1 - 3.6e-11 43.3 0.4 1.9e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAK88159.1 - 2e-08 33.6 1.2 0.00011 21.3 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EAK88159.1 - 7.2e-08 32.6 0.1 1.2e-06 28.6 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EAK88159.1 - 1.2e-06 28.3 0.6 0.0018 17.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAK88159.1 - 3.3e-06 27.2 0.3 0.041 14.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain DnaB_C PF03796.10 EAK88159.1 - 1.1e-05 24.4 0.2 2.3e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 EAK88159.1 - 2.8e-05 23.3 1.4 0.0071 15.5 0.2 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EAK88159.1 - 3.5e-05 24.6 0.7 0.00021 22.0 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EAK88159.1 - 4e-05 23.0 0.0 8.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EAK88159.1 - 0.00013 21.5 0.2 0.096 12.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 EAK88159.1 - 0.00017 20.7 0.4 0.00045 19.3 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin DUF2075 PF09848.4 EAK88159.1 - 0.00018 20.5 0.0 0.00053 19.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) CPT PF07931.7 EAK88159.1 - 0.00055 19.5 0.1 0.031 13.8 0.1 2.8 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.1 EAK88159.1 - 0.00073 19.2 0.1 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EAK88159.1 - 0.0014 18.9 2.8 0.0074 16.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 EAK88159.1 - 0.0014 18.5 1.0 1 9.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain KaiC PF06745.8 EAK88159.1 - 0.0018 17.4 1.7 0.0018 17.4 1.2 2.1 2 1 1 3 3 3 1 KaiC NACHT PF05729.7 EAK88159.1 - 0.0037 16.9 0.0 0.0076 15.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DNA_pol3_delta2 PF13177.1 EAK88159.1 - 0.0037 16.9 0.5 0.04 13.5 0.0 2.6 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Parvo_NS1 PF01057.12 EAK88159.1 - 0.0069 15.2 0.1 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.12 EAK88159.1 - 0.0092 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zot PF05707.7 EAK88159.1 - 0.012 15.1 0.1 5.4 6.4 0.0 2.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) PIF1 PF05970.9 EAK88159.1 - 0.013 14.4 0.2 1.3 7.9 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Sigma54_activ_2 PF14532.1 EAK88159.1 - 0.015 15.3 0.0 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain UPF0079 PF02367.12 EAK88159.1 - 0.018 14.6 0.1 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EAK88159.1 - 0.022 14.6 0.1 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EAK88159.1 - 0.039 13.5 0.5 0.2 11.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EAK88159.1 - 0.045 13.9 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 1 0 RNA helicase TFIID-31kDa PF02291.10 EAK88159.1 - 0.055 13.2 0.2 0.1 12.3 0.2 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit AAA_11 PF13086.1 EAK88159.1 - 0.069 12.7 0.9 0.09 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EAK88159.1 - 0.17 11.4 0.4 0.73 9.4 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EAK88159.1 - 0.95 9.7 9.0 44 4.2 6.3 2.3 1 1 0 1 1 1 0 AAA domain Glycos_transf_2 PF00535.21 EAK88160.1 - 9.6e-25 87.2 0.0 1.9e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EAK88160.1 - 1e-15 57.8 1.6 1.7e-15 57.1 1.1 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 EAK88160.1 - 5e-10 38.7 0.3 1e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EAK88160.1 - 2.3e-09 36.7 0.0 4.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 EAK88160.1 - 1.2e-07 31.7 0.0 2.2e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 PPR_2 PF13041.1 EAK88160.1 - 0.039 13.9 0.1 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 PPR repeat family Ank_2 PF12796.2 EAK88161.1 - 1.1e-29 102.6 1.2 9.5e-20 70.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EAK88161.1 - 1.9e-22 77.0 1.0 1.4e-05 24.8 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.25 EAK88161.1 - 4.8e-22 76.5 0.8 5.5e-06 25.9 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EAK88161.1 - 2.6e-21 75.5 1.5 2.9e-09 37.2 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Bromodomain PF00439.20 EAK88161.1 - 3.7e-18 65.2 0.1 8e-18 64.1 0.1 1.6 1 0 0 1 1 1 1 Bromodomain Ank_5 PF13857.1 EAK88161.1 - 2.4e-15 56.1 1.6 2.8e-06 27.3 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) gag-asp_proteas PF13975.1 EAK88161.1 - 0.026 14.3 0.0 10 6.0 0.0 2.9 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease FlaC_arch PF05377.6 EAK88161.1 - 0.18 11.7 1.1 10 6.0 0.5 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) MSG PF02349.10 EAK88161.1 - 0.92 9.5 4.9 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 Major surface glycoprotein Actin PF00022.14 EAK88162.1 - 2.6e-43 147.9 0.0 3.1e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Actin DUF1279 PF06916.8 EAK88163.1 - 3.6e-20 72.0 1.1 5.7e-20 71.4 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Transp_cyt_pur PF02133.10 EAK88165.1 - 0.011 14.2 0.0 0.014 13.9 0.0 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin YajC PF02699.10 EAK88165.1 - 0.15 11.7 1.8 0.4 10.3 1.2 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit KKLCAg1 PF15204.1 EAK88165.1 - 0.19 11.7 1.4 0.32 11.0 0.8 1.5 1 1 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 Symplekin_C PF12295.3 EAK88166.1 - 5.6e-48 163.2 3.5 5.6e-48 163.2 2.4 4.6 5 0 0 5 5 5 1 Symplekin tight junction protein C terminal ATP_bind_3 PF01171.15 EAK88167.1 - 3.8e-16 59.1 0.0 6.1e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 PP-loop family PAPS_reduct PF01507.14 EAK88167.1 - 0.0006 19.6 0.0 0.0028 17.5 0.0 1.9 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.16 EAK88167.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase RecR PF02132.10 EAK88167.1 - 2.2 7.7 8.0 0.41 10.1 2.4 2.1 2 0 0 2 2 2 0 RecR protein Fer4_9 PF13187.1 EAK88167.1 - 7.4 6.9 10.3 0.2 11.9 0.6 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain tRNA_m1G_MT PF01746.16 EAK88168.1 - 8.2e-22 77.6 0.3 1.3e-21 77.0 0.2 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase TPK_B1_binding PF04265.9 EAK88169.1 - 0.071 12.8 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain Methyltransf_12 PF08242.7 EAK88169.1 - 0.17 12.3 3.0 5.1 7.6 0.3 2.2 2 0 0 2 2 2 0 Methyltransferase domain Proteasom_Rpn13 PF04683.8 EAK88170.1 - 3.5e-15 55.8 0.3 6.1e-15 55.0 0.2 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF2853 PF11015.3 EAK88170.1 - 0.035 14.5 0.0 0.16 12.4 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2853) COPI_C PF06957.6 EAK88170.1 - 0.055 12.0 0.0 0.076 11.5 0.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF3198 PF11433.3 EAK88170.1 - 0.43 10.4 3.7 7.9 6.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3198) RNase_HII PF01351.13 EAK88170.1 - 2.4 7.7 5.1 1.9 8.0 2.7 1.5 1 1 0 1 1 1 0 Ribonuclease HII Peptidase_S9 PF00326.16 EAK88171.1 - 3.7e-07 29.5 0.0 9.6e-06 24.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAK88171.1 - 9.3e-05 22.2 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EAK88171.1 - 0.00035 20.0 0.5 0.036 13.5 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF1749 PF08538.5 EAK88171.1 - 0.0093 14.8 0.1 0.018 13.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) FSH1 PF03959.8 EAK88171.1 - 0.014 14.8 0.0 0.032 13.6 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.9 EAK88171.1 - 0.05 12.7 0.1 0.087 12.0 0.1 1.3 1 0 0 1 1 1 0 Secretory lipase BAAT_C PF08840.6 EAK88171.1 - 0.11 12.2 0.1 0.93 9.1 0.1 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal SET PF00856.23 EAK88172.1 - 1.8e-24 86.8 1.9 2.7e-24 86.2 0.3 2.1 2 0 0 2 2 2 1 SET domain PHD PF00628.24 EAK88172.1 - 6.7e-08 32.0 69.7 4.5e-06 26.2 4.9 7.0 7 0 0 7 7 7 4 PHD-finger Rad51 PF08423.6 EAK88173.1 - 4.7e-129 428.7 0.1 5.9e-129 428.4 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EAK88173.1 - 2.5e-12 46.5 0.0 3.7e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EAK88173.1 - 7.1e-10 38.4 0.1 1.1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EAK88173.1 - 3.6e-08 33.4 0.0 7.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 EAK88173.1 - 3e-06 26.5 0.5 7.6e-06 25.1 0.3 1.8 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 EAK88173.1 - 0.03 14.4 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PPC PF04151.10 EAK88175.1 - 3.5 8.6 6.8 7.4 7.6 0.5 2.7 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain BAMBI PF06211.7 EAK88176.1 - 0.056 13.4 0.1 24 4.9 0.0 4.0 3 0 0 3 3 3 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain CDC50 PF03381.10 EAK88177.1 - 8.5e-67 225.2 4.3 8.5e-67 225.2 2.9 2.4 1 1 2 3 3 3 1 LEM3 (ligand-effect modulator 3) family / CDC50 family T4_gp9_10 PF07880.6 EAK88177.1 - 0.78 8.7 7.3 0.31 10.0 3.1 1.7 2 0 0 2 2 2 0 Bacteriophage T4 gp9/10-like protein YfzA PF14118.1 EAK88177.1 - 0.93 9.6 6.9 11 6.2 1.0 2.7 2 0 0 2 2 2 0 YfzA-like protein Sigma70_ner PF04546.8 EAK88178.1 - 0.061 12.9 1.3 0.088 12.4 0.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region SSP160 PF06933.6 EAK88178.1 - 2.8 5.8 30.1 4.7 5.0 20.9 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BBP1_C PF15272.1 EAK88179.1 - 0.55 9.7 2.2 0.43 10.1 0.1 1.8 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal D5_N PF08706.6 EAK88180.1 - 0.1 12.6 4.4 0.94 9.5 0.0 3.4 3 0 0 3 3 3 0 D5 N terminal like Abhydrolase_2 PF02230.11 EAK88181.1 - 4e-13 49.3 0.0 7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EAK88181.1 - 1.2e-05 24.6 0.0 0.00098 18.3 0.0 2.3 1 1 1 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 EAK88181.1 - 0.00013 20.6 0.0 0.00035 19.1 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 EAK88181.1 - 0.00014 21.2 0.0 0.00022 20.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAK88181.1 - 0.00088 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EAK88181.1 - 0.0047 16.5 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAK88181.1 - 0.032 14.0 0.0 0.073 12.9 0.0 1.4 1 1 1 2 2 2 0 Alpha/beta hydrolase family BAAT_C PF08840.6 EAK88181.1 - 0.07 12.8 0.0 0.59 9.7 0.0 2.3 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal VTC PF09359.5 EAK88182.1 - 3.3e-102 341.2 3.0 3.3e-102 341.2 2.1 2.5 3 0 0 3 3 3 1 VTC domain SPX PF03105.14 EAK88182.1 - 0.00052 19.8 0.5 0.00052 19.8 0.3 2.9 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 EAK88182.1 - 0.022 14.9 1.0 0.1 12.8 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) F-box PF00646.28 EAK88183.1 - 0.032 13.8 0.2 0.22 11.2 0.0 2.6 2 0 0 2 2 2 0 F-box domain MFS_1 PF07690.11 EAK88185.1 - 0.0047 15.6 8.5 0.0047 15.6 5.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 EAK88185.1 - 0.077 11.1 1.4 0.16 10.0 0.3 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector YlbD_coat PF14071.1 EAK88185.1 - 2.3 8.2 8.7 3.9 7.5 6.0 1.3 1 0 0 1 1 1 0 Putative coat protein tRNA_anti-codon PF01336.20 EAK88188.1 - 5.2e-08 32.6 0.2 9.1e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain INT_SG_DDX_CT_C PF15300.1 EAK88189.1 - 0.031 13.7 0.2 0.056 12.9 0.1 1.4 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus LSM PF01423.17 EAK88189.1 - 0.14 11.7 0.7 0.45 10.0 0.1 2.0 2 0 0 2 2 2 0 LSM domain Rdx PF10262.4 EAK88190.1 - 5.3e-12 45.5 0.0 7.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Rdx family AAA_assoc PF14363.1 EAK88190.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA tRNA_m1G_MT PF01746.16 EAK88191.1 - 3.4e-14 52.8 0.1 3.4e-14 52.8 0.1 2.2 3 0 0 3 3 3 1 tRNA (Guanine-1)-methyltransferase FAM176 PF14851.1 EAK88193.1 - 0.047 13.3 0.2 0.047 13.3 0.2 2.0 2 0 0 2 2 2 0 FAM176 family DUF1510 PF07423.6 EAK88193.1 - 0.25 10.6 11.2 0.044 13.1 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SID-1_RNA_chan PF13965.1 EAK88193.1 - 0.81 7.7 4.4 0.25 9.4 1.3 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 DUF702 PF05142.7 EAK88193.1 - 1.9 8.6 6.8 1.1 9.4 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF1632 PF07857.7 EAK88193.1 - 3.3 6.8 5.2 1 8.5 1.5 1.7 1 1 1 2 2 2 0 CEO family (DUF1632) YMF19 PF02326.10 EAK88193.1 - 4.4 7.9 7.7 0.58 10.7 1.0 2.1 2 0 0 2 2 2 0 Plant ATP synthase F0 Mem_trans PF03547.13 EAK88193.1 - 4.9 5.3 6.9 0.54 8.4 1.5 1.7 1 1 1 2 2 2 0 Membrane transport protein SNF2_N PF00176.18 EAK88194.1 - 1.9e-31 108.9 1.8 3.5e-30 104.8 1.2 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAK88194.1 - 9.2e-10 38.2 0.0 7.6e-09 35.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAK88194.1 - 2.5e-06 27.4 0.7 5.2e-05 23.1 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EAK88194.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain C2 PF00168.25 EAK88195.1 - 8.6e-24 83.1 0.1 3.9e-06 26.6 0.0 5.7 6 0 0 6 6 6 4 C2 domain FerI PF08151.7 EAK88195.1 - 0.0013 18.7 0.0 0.16 12.0 0.0 2.7 2 0 0 2 2 2 1 FerI (NUC094) domain DNA_pol_A_exo1 PF01612.15 EAK88196.1 - 7.6e-38 129.7 0.1 1.5e-37 128.7 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 EAK88196.1 - 5.8e-11 41.9 0.0 1.6e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 HRDC domain PEPcase PF00311.12 EAK88198.1 - 3.5e-224 746.1 0.0 1.8e-135 452.8 0.0 3.1 3 0 0 3 3 3 3 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.1 EAK88198.1 - 0.00011 20.7 0.0 0.00038 18.9 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxylase HpcH_HpaI PF03328.9 EAK88198.1 - 0.0088 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family LOH1CR12 PF10158.4 EAK88198.1 - 0.16 11.7 4.6 0.17 11.6 0.1 3.2 4 0 0 4 4 4 0 Tumour suppressor protein EF-hand_1 PF00036.27 EAK88199.1 - 1.2e-31 105.5 11.7 7.6e-08 31.1 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EAK88199.1 - 1.2e-26 90.1 7.6 2.2e-07 30.1 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EAK88199.1 - 1.6e-26 92.1 6.9 7.2e-13 48.4 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EAK88199.1 - 4.3e-21 74.2 6.8 3.5e-12 45.7 0.8 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EAK88199.1 - 1.5e-15 55.7 10.7 7.3e-05 21.9 0.2 4.7 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.1 EAK88199.1 - 1.5e-13 50.4 0.2 9.4e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EAK88199.1 - 4.8e-05 23.0 3.2 0.14 11.9 0.0 2.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand DUF1636 PF07845.6 EAK88199.1 - 0.012 15.8 0.0 0.39 10.9 0.0 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF1636) TerB PF05099.8 EAK88199.1 - 0.04 13.6 2.5 7.6 6.2 0.1 2.8 2 1 1 3 3 3 0 Tellurite resistance protein TerB NaeI PF09126.5 EAK88199.1 - 0.091 11.3 0.4 1.1 7.7 0.0 2.0 2 0 0 2 2 2 0 Restriction endonuclease NaeI Ribosomal_L12 PF00542.14 EAK88199.1 - 0.17 11.9 2.7 0.37 10.8 0.1 2.5 2 1 1 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain EF-hand_10 PF14788.1 EAK88199.1 - 0.17 11.5 4.8 0.42 10.3 0.0 2.7 2 1 1 3 3 3 0 EF hand Toprim_2 PF13155.1 EAK88199.1 - 0.36 11.1 1.9 18 5.7 0.1 2.7 1 1 0 2 2 2 0 Toprim-like MgtE_N PF03448.12 EAK88199.1 - 0.73 10.1 7.2 0.18 12.1 1.0 2.4 2 1 0 2 2 2 0 MgtE intracellular N domain DUF3887 PF13026.1 EAK88199.1 - 0.74 10.1 5.4 3 8.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3887) Yae1_N PF09811.4 EAK88201.1 - 0.0053 16.2 12.4 0.011 15.2 8.6 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Myf5 PF12232.3 EAK88201.1 - 0.31 11.6 7.3 0.97 10.0 0.2 2.9 2 0 0 2 2 2 0 Myogenic determination factor 5 Daxx PF03344.10 EAK88201.1 - 2.9 6.2 44.2 4.4 5.6 30.6 1.3 1 0 0 1 1 1 0 Daxx Family Dapper PF15268.1 EAK88201.1 - 4.8 5.8 39.2 6.9 5.3 27.2 1.2 1 0 0 1 1 1 0 Dapper IncA PF04156.9 EAK88202.1 - 0.092 12.3 2.0 0.11 12.0 1.4 1.1 1 0 0 1 1 1 0 IncA protein Alpha_GJ PF03229.8 EAK88203.1 - 0.078 13.3 1.7 0.15 12.3 1.2 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J Ribosomal_S13_N PF08069.7 EAK88204.1 - 7.1e-28 96.2 0.2 1.4e-27 95.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EAK88204.1 - 2.4e-20 72.0 0.2 3.2e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 DUF1489 PF07370.6 EAK88204.1 - 0.1 12.1 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) LSM PF01423.17 EAK88205.1 - 1.5e-16 59.6 3.0 2.1e-16 59.2 2.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAK88205.1 - 0.0022 17.8 0.2 0.003 17.4 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.3 EAK88205.1 - 0.0096 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) DUF3247 PF11607.3 EAK88205.1 - 0.12 12.5 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) THDPS_M PF14789.1 EAK88206.1 - 0.0018 18.1 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 2 Tetrahydrodipicolinate N-succinyltransferase middle DAD PF02109.11 EAK88208.1 - 2e-31 108.3 4.5 2.9e-31 107.8 3.1 1.2 1 0 0 1 1 1 1 DAD family PAP2_C PF14360.1 EAK88208.1 - 1.8 8.9 6.3 0.34 11.1 0.8 2.1 1 1 1 2 2 2 0 PAP2 superfamily C-terminal Band_7 PF01145.20 EAK88209.1 - 2.4e-23 82.9 0.7 3.1e-23 82.5 0.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 EAK88209.1 - 0.042 13.8 2.2 0.081 12.9 1.5 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 Sin3_corepress PF08295.7 EAK88210.1 - 3.3e-39 132.6 0.4 1e-38 131.1 0.3 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 EAK88210.1 - 2.3e-29 100.7 4.3 1.7e-13 49.9 0.1 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat PDZ_2 PF13180.1 EAK88211.1 - 0.00033 20.4 0.0 0.0008 19.2 0.0 1.6 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.19 EAK88211.1 - 0.003 17.7 0.0 0.0063 16.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF1048 PF06304.6 EAK88211.1 - 0.061 13.6 0.1 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) GRASP55_65 PF04495.9 EAK88211.1 - 0.084 12.8 0.0 1 9.3 0.0 2.2 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain Beta-lactamase PF00144.19 EAK88212.1 - 1.3e-27 96.7 0.0 8.1e-27 94.0 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase Peptidase_S49_N PF08496.5 EAK88212.1 - 0.3 10.8 3.6 0.63 9.8 2.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Prefoldin PF02996.12 EAK88213.1 - 2.1e-20 72.5 2.5 2.9e-20 72.0 1.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Fib_alpha PF08702.5 EAK88213.1 - 0.022 14.8 0.6 0.022 14.8 0.4 2.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DASH_Duo1 PF08651.5 EAK88213.1 - 0.057 13.0 1.6 1.3 8.6 0.3 2.3 2 0 0 2 2 2 0 DASH complex subunit Duo1 IFT20 PF14931.1 EAK88213.1 - 0.081 12.8 7.4 0.59 10.0 0.1 2.2 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Prefoldin_2 PF01920.15 EAK88213.1 - 0.46 10.2 6.7 1.1 9.0 0.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit ubiquitin PF00240.18 EAK88214.1 - 4.3e-106 346.3 11.8 8.8e-35 117.9 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 EAK88214.1 - 1.1e-61 204.4 10.9 7.6e-20 70.3 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EAK88214.1 - 2.1e-21 75.9 4.1 1.8e-05 24.8 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EAK88214.1 - 1.6e-15 57.2 0.1 0.0015 18.2 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EAK88214.1 - 1.9e-11 43.8 1.1 0.049 13.5 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EAK88214.1 - 5.9e-10 39.2 0.2 0.19 11.9 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EAK88214.1 - 6.3e-09 35.6 1.1 0.27 11.1 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF2870 PF11069.3 EAK88214.1 - 7.1e-08 32.4 0.0 1.1 9.3 0.0 3.9 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EAK88214.1 - 8.3e-06 25.4 0.5 3.9 7.2 0.0 3.3 3 0 0 3 3 3 3 FlgD Ig-like domain USP7_C2 PF14533.1 EAK88214.1 - 7.8e-05 22.2 1.9 2.7 7.3 0.0 3.1 1 1 1 3 3 3 3 Ubiquitin-specific protease C-terminal Plexin_cytopl PF08337.7 EAK88214.1 - 0.00088 17.7 5.3 4.1 5.6 0.1 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain CTDII PF01556.13 EAK88214.1 - 0.0026 17.6 9.1 1.8 8.4 0.2 3.3 1 1 2 3 3 3 2 DnaJ C terminal domain FERM_N PF09379.5 EAK88214.1 - 0.0032 17.4 3.2 29 4.8 0.0 4.7 3 3 0 3 3 3 0 FERM N-terminal domain EMG1 PF03587.9 EAK88214.1 - 0.0038 16.5 0.1 14 4.9 0.0 3.1 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase YfmQ PF10787.4 EAK88214.1 - 0.017 14.4 0.2 35 3.7 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein from bacillus cereus group GABP-alpha PF11620.3 EAK88214.1 - 0.018 15.0 1.0 42 4.2 0.0 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain DUF3781 PF12636.2 EAK88214.1 - 0.28 11.1 1.5 1.1e+02 2.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) YajC PF02699.10 EAK88214.1 - 0.75 9.5 4.1 40 3.9 0.0 3.1 3 0 0 3 3 3 0 Preprotein translocase subunit Sec_GG PF07549.9 EAK88214.1 - 2.3 7.5 5.5 1.9e+02 1.6 0.0 4.7 5 0 0 5 5 5 0 SecD/SecF GG Motif Peptidase_M17 PF00883.16 EAK88215.1 - 5.9e-101 337.4 0.1 7.5e-101 337.0 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain His_Phos_1 PF00300.17 EAK88216.1 - 7.6e-29 100.8 0.2 1.6e-28 99.8 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Med6 PF04934.9 EAK88217.1 - 1.9e-17 63.1 0.1 2.6e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Pkinase PF00069.20 EAK88218.1 - 1.9e-80 269.7 0.0 2.2e-80 269.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK88218.1 - 3.2e-35 121.4 0.0 4.3e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAK88218.1 - 8.1e-06 24.9 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAK88218.1 - 0.00019 21.2 0.0 0.021 14.5 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EAK88218.1 - 0.0082 15.5 0.3 0.032 13.5 0.1 1.7 1 1 1 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.6 EAK88218.1 - 0.088 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EAK88218.1 - 0.14 11.2 0.6 0.37 9.8 0.4 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_N PF08240.7 EAK88219.1 - 2.6e-28 97.9 5.8 2.6e-28 97.9 4.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAK88219.1 - 1.2e-21 76.6 0.0 2.4e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EAK88219.1 - 0.0088 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EAK88219.1 - 0.025 14.4 0.1 0.053 13.3 0.1 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EAK88219.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EAK88219.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Arf PF00025.16 EAK88220.1 - 1.1e-11 44.2 0.0 1.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family T2SE PF00437.15 EAK88220.1 - 0.00014 20.8 0.2 0.0002 20.3 0.1 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein SRPRB PF09439.5 EAK88220.1 - 0.0022 17.2 0.1 0.0042 16.3 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 EAK88220.1 - 0.0066 16.8 0.0 0.013 15.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 EAK88220.1 - 0.013 14.6 0.1 0.018 14.2 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EAK88220.1 - 0.024 14.1 0.5 0.051 13.1 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 EAK88220.1 - 0.043 13.2 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Ras family cobW PF02492.14 EAK88220.1 - 0.054 12.9 0.3 0.12 11.8 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EAK88220.1 - 0.06 13.8 0.0 0.09 13.2 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 EAK88220.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EAK88220.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAK88220.1 - 0.58 10.4 2.5 1 9.6 1.7 1.6 1 1 0 1 1 1 0 AAA domain Cofilin_ADF PF00241.15 EAK88221.1 - 6.6e-28 97.1 0.1 7.7e-28 96.9 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Alpha-amylase PF00128.19 EAK88222.1 - 2.6e-56 191.3 2.7 2.6e-56 191.3 1.9 1.6 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EAK88222.1 - 2e-06 27.8 0.8 0.00023 21.2 0.0 2.7 2 0 0 2 2 2 2 Alpha amylase, C-terminal all-beta domain Glyco_hydro_70 PF02324.11 EAK88222.1 - 0.0028 15.4 0.0 0.55 7.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 70 DnaJ PF00226.26 EAK88223.1 - 3e-24 84.5 0.5 1.1e-23 82.6 0.3 2.1 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.2 EAK88223.1 - 3.1e-09 36.6 13.8 9.4e-09 35.1 5.0 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EAK88223.1 - 1.2e-07 31.6 6.0 1.2e-07 31.6 4.2 3.3 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EAK88223.1 - 1.2e-07 31.7 8.6 9.7e-05 22.4 1.2 4.5 5 0 0 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EAK88223.1 - 9.1e-06 25.7 10.0 0.0027 17.9 2.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EAK88223.1 - 0.00012 21.8 2.9 0.15 12.0 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EAK88223.1 - 0.00035 20.7 7.9 0.039 14.3 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-UBP PF02148.14 EAK88223.1 - 0.037 14.1 1.4 0.14 12.2 0.2 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Mut7-C PF01927.11 EAK88223.1 - 0.11 12.4 7.4 4 7.3 2.5 2.6 2 0 0 2 2 2 0 Mut7-C RNAse domain C1_4 PF07975.7 EAK88223.1 - 0.69 9.9 3.3 25 4.9 0.1 2.8 2 0 0 2 2 2 0 TFIIH C1-like domain zf-H2C2_2 PF13465.1 EAK88223.1 - 2 8.8 6.9 1.1 9.6 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Plus-3 PF03126.13 EAK88224.1 - 7.5e-09 35.6 0.1 8.2e-08 32.2 0.0 2.9 2 0 0 2 2 2 1 Plus-3 domain Ribosomal_S7e PF01251.13 EAK88225.1 - 8.9e-69 230.7 0.1 1e-68 230.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Stap_Strp_toxin PF01123.15 EAK88225.1 - 0.0084 16.5 0.1 0.021 15.2 0.0 1.7 2 0 0 2 2 2 1 Staphylococcal/Streptococcal toxin, OB-fold domain Histone PF00125.19 EAK88226.1 - 1.1e-18 67.1 0.4 1.5e-18 66.6 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAK88226.1 - 7.3e-06 25.9 0.7 1.5e-05 24.9 0.5 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3825 PF12873.2 EAK88226.1 - 0.0028 16.8 0.9 0.034 13.2 0.1 2.1 1 1 2 3 3 3 1 Domain of unknown function (DUF3825) TFIID_20kDa PF03847.8 EAK88226.1 - 0.0066 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Gag_p24 PF00607.15 EAK88226.1 - 0.02 14.4 0.4 0.04 13.4 0.2 1.5 1 1 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) FAST_2 PF08368.7 EAK88226.1 - 0.12 12.7 0.3 0.97 9.8 0.1 2.1 1 1 1 2 2 2 0 FAST kinase-like protein, subdomain 2 Glyco_transf_8 PF01501.15 EAK88227.1 - 2.4e-17 63.0 1.7 3e-17 62.7 1.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 WD40 PF00400.27 EAK88228.1 - 6.8e-10 38.4 3.1 3.7e-05 23.4 0.2 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 EAK88228.1 - 0.078 12.7 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region vATP-synt_AC39 PF01992.11 EAK88229.1 - 5.2e-57 193.4 0.7 2.6e-56 191.2 0.5 1.8 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit ADK PF00406.17 EAK88230.1 - 4.3e-53 179.2 0.0 5.3e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EAK88230.1 - 4.5e-16 58.2 0.1 9.4e-16 57.1 0.1 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EAK88230.1 - 1.7e-08 35.2 0.5 3.1e-08 34.4 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAK88230.1 - 1.5e-05 24.9 0.0 3.4e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAK88230.1 - 0.00087 19.5 0.3 0.0037 17.5 0.2 1.9 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EAK88230.1 - 0.021 13.9 0.1 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.12 EAK88230.1 - 0.06 12.7 0.1 1.3 8.3 0.1 2.5 3 0 0 3 3 3 0 Thymidylate kinase TFIIB PF00382.14 EAK88231.1 - 4.2e-25 87.3 0.3 5.5e-12 45.3 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EAK88231.1 - 2.2e-12 46.9 4.6 2.2e-12 46.9 3.2 2.1 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EAK88231.1 - 2.5e-10 39.4 1.5 2.5e-10 39.4 1.1 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EAK88231.1 - 0.0085 15.2 1.3 0.031 13.4 0.8 2.0 1 1 1 2 2 2 2 zinc-ribbon domain RRN7 PF11781.3 EAK88231.1 - 0.027 13.9 0.4 0.06 12.8 0.3 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 EAK88231.1 - 0.058 13.2 0.6 0.16 11.7 0.4 1.7 1 0 0 1 1 1 0 Double zinc ribbon DnaJ PF00226.26 EAK88232.1 - 6.7e-18 64.1 1.6 7.6e-18 64.0 0.2 1.8 2 0 0 2 2 2 1 DnaJ domain Nol1_Nop2_Fmu PF01189.12 EAK88233.1 - 2.9e-26 92.4 0.0 9.6e-23 80.9 0.0 3.2 2 1 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 EAK88233.1 - 0.0043 17.0 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF4193 PF13834.1 EAK88233.1 - 0.033 14.3 0.5 0.033 14.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) Enolase_C PF00113.17 EAK88234.1 - 5.7e-140 465.4 0.0 7.2e-140 465.0 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EAK88234.1 - 1e-54 184.0 0.1 1.5e-54 183.4 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 EAK88234.1 - 0.008 16.6 0.0 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 EAK88234.1 - 0.01 15.8 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like PH PF00169.24 EAK88235.1 - 5.6e-22 77.9 0.4 6.7e-22 77.6 0.3 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EAK88235.1 - 2.4e-08 34.2 2.4 4e-07 30.2 1.7 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EAK88235.1 - 5.8e-06 26.1 0.1 1.1e-05 25.2 0.1 1.4 1 1 0 1 1 1 1 PH domain PH_8 PF15409.1 EAK88235.1 - 2.5e-05 24.2 0.1 3.6e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 EAK88235.1 - 0.0074 16.4 0.1 0.015 15.4 0.0 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_4 PF15404.1 EAK88235.1 - 0.095 12.2 0.0 1.9 8.0 0.0 2.0 1 1 1 2 2 2 0 Pleckstrin homology domain DUF1762 PF08574.5 EAK88235.1 - 0.11 12.8 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1762) AAA PF00004.24 EAK88236.1 - 4.9e-84 279.1 0.0 1.2e-48 164.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAK88236.1 - 2.2e-12 47.3 0.0 2.7e-06 27.4 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 EAK88236.1 - 1.1e-11 44.2 0.0 2.6e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EAK88236.1 - 2.6e-10 40.0 3.5 0.2 11.0 0.0 4.4 2 2 2 4 4 4 4 AAA domain AAA_17 PF13207.1 EAK88236.1 - 2.7e-10 41.1 0.0 0.00024 21.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EAK88236.1 - 7.6e-10 39.0 0.2 0.0019 18.3 0.0 4.6 3 2 2 5 5 4 2 AAA domain AAA_33 PF13671.1 EAK88236.1 - 7.9e-10 38.7 0.0 0.00092 19.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EAK88236.1 - 6.2e-09 35.0 0.1 0.0017 17.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EAK88236.1 - 7.7e-09 35.1 1.3 0.0028 17.3 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain AAA_5 PF07728.9 EAK88236.1 - 8.2e-09 35.3 0.7 0.0037 17.0 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EAK88236.1 - 4.8e-08 32.6 0.1 0.0051 16.2 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EAK88236.1 - 5.1e-08 32.8 0.0 0.00064 19.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EAK88236.1 - 2.6e-07 29.9 0.0 0.00028 20.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_2 PF07724.9 EAK88236.1 - 1.2e-06 28.5 0.1 0.00023 21.1 0.0 3.4 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EAK88236.1 - 6.9e-06 26.1 0.0 0.014 15.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Arch_ATPase PF01637.13 EAK88236.1 - 1.2e-05 25.0 1.7 0.1 12.2 0.0 4.2 2 2 1 3 3 3 1 Archaeal ATPase AAA_18 PF13238.1 EAK88236.1 - 1.4e-05 25.3 1.4 0.026 14.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 EAK88236.1 - 1.6e-05 25.2 0.7 0.011 16.0 0.0 3.0 3 0 0 3 3 2 1 ABC transporter NACHT PF05729.7 EAK88236.1 - 2.6e-05 23.9 0.4 0.1 12.2 0.0 3.7 4 0 0 4 4 4 1 NACHT domain Mg_chelatase PF01078.16 EAK88236.1 - 2.7e-05 23.4 0.9 0.024 13.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EAK88236.1 - 0.00023 20.6 0.0 0.16 11.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EAK88236.1 - 0.00028 20.9 0.1 0.051 13.6 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.11 EAK88236.1 - 0.0003 20.0 0.1 0.68 9.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_28 PF13521.1 EAK88236.1 - 0.00062 19.7 0.0 0.058 13.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EAK88236.1 - 0.00083 18.9 0.0 0.5 9.9 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EAK88236.1 - 0.00095 18.3 0.5 0.5 9.4 0.0 3.6 4 0 0 4 4 4 1 KaiC AAA_11 PF13086.1 EAK88236.1 - 0.0013 18.3 0.5 1.2 8.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 EAK88236.1 - 0.0022 17.5 0.4 0.074 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EAK88236.1 - 0.0026 16.5 0.1 0.013 14.2 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Parvo_NS1 PF01057.12 EAK88236.1 - 0.0041 16.0 0.0 0.1 11.4 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EAK88236.1 - 0.0052 15.7 0.0 0.085 11.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) SKI PF01202.17 EAK88236.1 - 0.0088 15.9 1.0 0.56 10.0 0.0 3.0 3 0 0 3 3 3 1 Shikimate kinase Cytidylate_kin2 PF13189.1 EAK88236.1 - 0.0092 15.9 0.2 2.5 7.9 0.0 3.1 3 0 0 3 3 3 1 Cytidylate kinase-like family Viral_helicase1 PF01443.13 EAK88236.1 - 0.012 15.1 0.1 0.084 12.3 0.0 2.4 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 EAK88236.1 - 0.015 14.3 0.1 0.76 8.7 0.0 3.4 3 1 1 4 4 4 0 KAP family P-loop domain UPF0079 PF02367.12 EAK88236.1 - 0.018 14.6 0.1 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 EAK88236.1 - 0.031 13.2 0.2 7.4 5.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EAK88236.1 - 0.033 13.6 1.3 6.2 6.1 0.0 3.3 3 1 0 3 3 3 0 AAA-like domain NB-ARC PF00931.17 EAK88236.1 - 0.039 12.7 0.2 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain IPT PF01745.11 EAK88236.1 - 0.062 12.4 0.2 2.1 7.4 0.0 2.7 3 0 0 3 3 3 0 Isopentenyl transferase ATP-synt_ab PF00006.20 EAK88236.1 - 0.071 12.6 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 EAK88236.1 - 0.15 11.6 0.1 11 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EAK88236.1 - 3.1 6.9 5.4 22 4.1 0.0 3.1 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Cpn60_TCP1 PF00118.19 EAK88237.1 - 7.7e-134 446.9 15.0 9.5e-134 446.6 10.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Isy1 PF06246.7 EAK88238.1 - 9.6e-23 80.8 4.2 1.2e-22 80.5 2.9 1.1 1 0 0 1 1 1 1 Isy1-like splicing family SpoVIF PF14069.1 EAK88238.1 - 0.0016 18.1 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 Stage VI sporulation protein F DUF3441 PF11923.3 EAK88239.1 - 4.6e-24 84.1 0.0 1.8e-23 82.2 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 EAK88239.1 - 1.5e-23 82.4 0.1 5.4e-23 80.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF814) FbpA PF05833.6 EAK88239.1 - 3.8e-18 65.2 0.0 3.8e-18 65.2 0.0 3.5 3 1 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) HORMA PF02301.13 EAK88240.1 - 1.5e-56 191.2 7.5 3.5e-56 189.9 0.7 2.2 2 0 0 2 2 2 2 HORMA domain UPF0066 PF01980.11 EAK88241.1 - 7.2e-27 93.7 0.2 9.2e-26 90.1 0.0 2.4 2 1 0 2 2 2 1 Uncharacterised protein family UPF0066 Aa_trans PF01490.13 EAK88242.1 - 1.7e-36 125.6 44.0 5.6e-36 123.9 30.5 1.7 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein LRRC37AB_C PF14914.1 EAK88242.1 - 8.5 5.7 7.6 17 4.7 0.3 3.4 3 0 0 3 3 3 0 LRRC37A/B like protein 1 C-terminal domain zf-CW PF07496.10 EAK88243.1 - 4.7e-16 58.2 5.0 4.7e-16 58.2 3.5 2.2 2 0 0 2 2 2 1 CW-type Zinc Finger IF-2B PF01008.12 EAK88244.1 - 4.2e-34 117.8 0.0 5e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Robl_LC7 PF03259.12 EAK88245.1 - 6.5e-06 25.6 0.0 9.3e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain NDK PF00334.14 EAK88246.1 - 6.6e-51 171.6 0.0 8.5e-51 171.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase TRAP_alpha PF03896.11 EAK88246.1 - 0.028 13.4 0.1 0.071 12.0 0.0 1.6 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit zf-DHHC PF01529.15 EAK88247.1 - 2.3e-28 98.7 17.3 2.3e-28 98.7 12.0 2.5 1 1 1 2 2 2 1 DHHC palmitoyltransferase Wzy_C PF04932.10 EAK88247.1 - 0.1 12.4 5.8 2.7 7.7 2.3 2.3 2 0 0 2 2 2 0 O-Antigen ligase RRM_1 PF00076.17 EAK88248.1 - 3.3e-14 52.2 3.8 1.9e-10 40.2 0.4 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK88248.1 - 6.1e-11 42.1 0.5 1.3e-06 28.2 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK88248.1 - 0.00042 20.0 0.3 0.032 14.0 0.1 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Beta-Casp PF10996.3 EAK88249.1 - 1e-21 77.2 0.0 2.3e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EAK88249.1 - 1e-12 48.1 0.1 5.7e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EAK88249.1 - 3.1e-10 39.7 0.1 6.6e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EAK88249.1 - 6.6e-10 38.8 0.0 1.6e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EAK88249.1 - 0.0018 17.9 0.1 0.0085 15.8 0.0 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Acyltransferase PF01553.16 EAK88250.1 - 7.3e-13 48.1 0.0 1.7e-12 46.9 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase Allexi_40kDa PF05549.6 EAK88251.1 - 0.00011 21.6 3.8 0.00059 19.2 0.1 2.3 1 1 0 2 2 2 1 Allexivirus 40kDa protein Reo_sigmaC PF04582.7 EAK88251.1 - 0.002 17.3 4.1 0.0024 17.1 1.4 1.8 1 1 1 2 2 2 2 Reovirus sigma C capsid protein APG6 PF04111.7 EAK88251.1 - 0.1 11.6 16.8 0.1 11.6 4.0 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4337 PF14235.1 EAK88251.1 - 0.18 11.5 1.1 0.33 10.7 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Baculo_PEP_C PF04513.7 EAK88251.1 - 0.34 10.7 6.5 1.9 8.2 4.5 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EAK88251.1 - 0.38 10.3 16.4 1.1 8.8 7.5 2.3 1 1 1 2 2 2 0 IncA protein Cep57_CLD_2 PF14197.1 EAK88251.1 - 0.45 10.5 11.7 0.39 10.6 5.5 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TBPIP PF07106.8 EAK88251.1 - 1.3 8.5 20.7 0.4 10.2 1.1 2.8 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EAK88251.1 - 1.3 9.3 13.6 4.7 7.6 3.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Snapin_Pallidin PF14712.1 EAK88251.1 - 1.9 8.8 13.1 0.62 10.4 2.3 3.2 1 1 2 3 3 3 0 Snapin/Pallidin BLOC1_2 PF10046.4 EAK88251.1 - 2.1 8.5 18.7 3 8.0 5.9 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.6 EAK88251.1 - 4.2 7.8 9.6 1.4 9.3 1.5 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CCDC155 PF14662.1 EAK88251.1 - 4.3 6.8 16.0 2.5 7.6 8.7 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 V_ATPase_I PF01496.14 EAK88251.1 - 4.6 4.9 15.0 11 3.7 10.4 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EAK88251.1 - 7.2 6.7 17.9 0.61 10.2 2.6 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ribosomal_L13 PF00572.13 EAK88252.1 - 1.6e-22 79.9 0.0 3e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 ParA PF10609.4 EAK88253.1 - 1.2e-35 121.1 0.0 2.8e-35 120.0 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EAK88253.1 - 8.5e-19 67.7 0.3 1.7e-18 66.7 0.0 1.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF971 PF06155.7 EAK88253.1 - 5.6e-10 39.5 0.0 1.3e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) DUF59 PF01883.14 EAK88253.1 - 6.8e-10 38.8 0.0 3.5e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF59 AAA_31 PF13614.1 EAK88253.1 - 2.5e-09 37.2 0.1 1.1e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EAK88253.1 - 2.6e-06 26.7 0.1 1.1e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EAK88253.1 - 5e-06 25.7 2.5 0.0055 15.7 0.8 3.0 2 1 1 3 3 3 2 Anion-transporting ATPase Fer4_NifH PF00142.13 EAK88253.1 - 0.0016 17.7 0.0 0.0029 16.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YhjQ PF06564.7 EAK88253.1 - 0.032 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 YhjQ protein UPF0066 PF01980.11 EAK88254.1 - 1e-35 122.2 0.0 2.4e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0066 Arg_tRNA_synt_N PF03485.11 EAK88254.1 - 0.00092 19.7 0.4 0.08 13.4 0.0 2.6 2 1 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DUF867 PF05908.6 EAK88254.1 - 0.12 11.4 0.1 0.3 10.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF867) Pkinase PF00069.20 EAK88255.1 - 4.6e-80 268.5 0.4 7.6e-80 267.8 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK88255.1 - 9.7e-44 149.3 0.4 2.1e-43 148.2 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EAK88255.1 - 1.3e-27 92.9 12.0 1.6e-06 27.0 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EAK88255.1 - 1.1e-22 79.9 7.6 3.8e-10 39.7 0.8 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EAK88255.1 - 3.1e-21 73.2 7.0 7.1e-06 25.4 0.1 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EAK88255.1 - 1e-20 72.0 10.5 1.7e-06 27.0 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EAK88255.1 - 2.8e-20 71.6 12.5 6.1e-05 22.5 0.1 4.9 3 1 2 5 5 5 4 EF-hand domain pair Kinase-like PF14531.1 EAK88255.1 - 2.1e-08 33.5 0.1 6.8e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like SPARC_Ca_bdg PF10591.4 EAK88255.1 - 1.1e-07 31.8 1.0 0.0065 16.4 0.1 2.9 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EAK88255.1 - 1.7e-06 27.6 5.7 0.0017 18.0 0.5 3.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.9 EAK88255.1 - 0.0061 15.6 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAK88255.1 - 0.0066 16.2 0.0 0.024 14.3 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EAK88255.1 - 0.013 14.8 0.1 0.034 13.4 0.1 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PP2C PF00481.16 EAK88256.1 - 3.6e-33 115.0 0.0 4.1e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EAK88256.1 - 0.0039 16.6 0.0 0.012 15.0 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Malic_M PF03949.10 EAK88257.1 - 7.2e-79 264.9 0.1 9.4e-79 264.5 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EAK88257.1 - 5.2e-56 189.0 0.0 9.4e-56 188.2 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF187 PF02638.10 EAK88257.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 YIF1 PF03878.10 EAK88258.1 - 3.2e-27 95.2 8.4 4.3e-27 94.8 5.8 1.1 1 0 0 1 1 1 1 YIF1 RRM_1 PF00076.17 EAK88259.1 - 8.3e-39 131.0 0.0 4.1e-21 74.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK88259.1 - 3.4e-32 110.2 0.0 1.5e-17 63.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK88259.1 - 1.7e-16 59.8 0.0 3.5e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAK88259.1 - 0.00037 20.2 0.1 0.15 11.8 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Laminin_G_1 PF00054.18 EAK88259.1 - 0.036 14.0 0.4 3.3 7.7 0.1 2.6 2 0 0 2 2 2 0 Laminin G domain IMCp PF12314.3 EAK88260.1 - 2e-25 88.7 114.1 3.5e-10 39.8 16.8 5.2 1 1 4 5 5 5 5 Inner membrane complex protein DUF4326 PF14216.1 EAK88261.1 - 0.083 13.4 1.5 0.85 10.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) Zip PF02535.17 EAK88261.1 - 2 7.3 5.9 3 6.7 4.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ala_racemase_N PF01168.15 EAK88262.1 - 2.5e-30 105.6 0.0 2.9e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Sigma_1s PF02454.11 EAK88262.1 - 0.038 13.7 0.6 4.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Sigma 1s protein ATP-synt_D PF01813.12 EAK88263.1 - 1.3e-63 214.1 1.8 1.8e-63 213.6 1.2 1.2 1 0 0 1 1 1 1 ATP synthase subunit D GDPD PF03009.12 EAK88264.1 - 1.2e-27 97.0 0.0 1.3e-19 70.7 0.0 2.3 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family zf-C3HC4_2 PF13923.1 EAK88265.1 - 2.9e-09 36.8 8.9 1e-07 31.8 3.1 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAK88265.1 - 5.8e-09 35.4 6.6 1.9e-08 33.8 4.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAK88265.1 - 1.5e-08 34.3 8.0 6.1e-08 32.3 5.5 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EAK88265.1 - 8.8e-08 31.6 6.7 3e-07 29.9 4.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK88265.1 - 1.9e-07 30.6 8.0 3.3e-07 29.9 1.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EAK88265.1 - 5.3e-06 26.4 6.5 1.1e-05 25.3 4.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EAK88265.1 - 9.1e-05 22.0 4.4 0.00058 19.5 3.0 2.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAK88265.1 - 0.0003 20.6 7.4 0.0033 17.2 2.1 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EAK88265.1 - 0.00055 19.4 6.2 0.0018 17.7 2.2 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 EAK88265.1 - 0.007 16.1 1.3 0.007 16.1 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1272) zf-RING_6 PF14835.1 EAK88265.1 - 0.016 14.9 1.2 0.016 14.9 0.8 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EAK88265.1 - 0.05 13.4 4.3 0.14 12.0 3.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EAK88265.1 - 0.074 12.5 5.8 1.1 8.8 2.0 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger SOBP PF15279.1 EAK88265.1 - 0.38 11.1 10.6 0.27 11.5 6.4 1.4 1 1 0 1 1 1 0 Sine oculis-binding protein C1_4 PF07975.7 EAK88265.1 - 0.7 9.9 4.9 1.2 9.1 0.5 2.9 2 0 0 2 2 2 0 TFIIH C1-like domain DZR PF12773.2 EAK88265.1 - 2 8.3 8.3 2.1 8.2 2.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-FPG_IleRS PF06827.9 EAK88265.1 - 2.8 7.6 9.8 2.9 7.6 0.6 3.2 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf-P11 PF03854.9 EAK88265.1 - 3.1 7.3 7.3 0.29 10.6 1.4 2.0 2 0 0 2 2 2 0 P-11 zinc finger Rad50_zn_hook PF04423.9 EAK88265.1 - 5.3 6.5 7.1 1.3 8.5 0.2 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Nse PF11789.3 EAK88265.1 - 7.7 6.1 7.8 59 3.2 4.7 2.7 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit CAP_C PF08603.6 EAK88266.1 - 1.9e-50 170.3 6.9 1.9e-50 170.3 4.8 1.3 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EAK88266.1 - 7.2e-06 25.3 4.4 1.3e-05 24.6 3.0 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C G2F PF07474.7 EAK88266.1 - 0.11 11.8 0.1 0.45 9.8 0.0 1.8 1 1 0 1 1 1 0 G2F domain DUF2205 PF10224.4 EAK88267.1 - 0.012 15.1 6.4 0.012 15.1 4.4 2.8 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF869 PF05911.6 EAK88267.1 - 3.5 5.7 31.5 4.6 5.3 21.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) HEAT_2 PF13646.1 EAK88268.1 - 0.13 12.5 0.0 8.6 6.7 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats G-patch PF01585.18 EAK88270.1 - 4.1e-15 55.2 2.8 9e-15 54.1 1.9 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EAK88270.1 - 1.8e-09 37.3 0.1 1.8e-09 37.3 0.1 2.9 2 1 0 2 2 2 1 DExH-box splicing factor binding site GEMIN8 PF15348.1 EAK88270.1 - 0.051 13.6 9.1 0.063 13.3 6.3 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Myb_DNA-binding PF00249.26 EAK88271.1 - 3.8e-19 68.4 7.1 9.6e-11 41.5 0.2 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_Cef PF11831.3 EAK88271.1 - 2.8e-16 59.4 6.7 2.8e-16 59.4 4.7 2.5 2 0 0 2 2 2 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 EAK88271.1 - 6.8e-16 58.1 5.2 2.5e-12 46.7 1.7 3.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain HPS3_C PF14763.1 EAK88272.1 - 0.0015 17.6 1.9 0.0037 16.2 0.1 2.2 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3, C-terminal ETRAMP PF09716.5 EAK88279.1 - 0.00087 19.1 1.3 0.0012 18.7 0.9 1.2 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) RE_MjaI PF09568.5 EAK88279.1 - 0.019 14.4 1.3 0.067 12.7 0.7 1.8 1 1 1 2 2 2 0 MjaI restriction endonuclease tRNA_anti-like PF12869.2 EAK88279.1 - 0.033 13.6 0.2 0.04 13.3 0.1 1.1 1 0 0 1 1 1 0 tRNA_anti-like HMG_box PF00505.14 EAK88279.1 - 0.039 14.2 0.3 0.057 13.7 0.2 1.2 1 0 0 1 1 1 0 HMG (high mobility group) box Borrelia_REV PF03978.8 EAK88279.1 - 0.046 13.4 2.3 0.054 13.2 1.6 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Serine_rich PF08824.5 EAK88279.1 - 0.058 13.1 0.1 0.073 12.7 0.0 1.1 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF4449 PF14613.1 EAK88279.1 - 0.12 12.3 1.6 0.15 11.9 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DUF4363 PF14276.1 EAK88279.1 - 0.14 11.9 2.2 1.6 8.4 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) UPF0118 PF01594.11 EAK88279.1 - 0.16 10.9 0.7 0.2 10.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 GIDA PF01134.17 EAK88279.1 - 0.18 10.6 2.0 0.2 10.5 1.4 1.0 1 0 0 1 1 1 0 Glucose inhibited division protein A GnsAB PF08178.6 EAK88279.1 - 0.43 10.2 0.2 0.43 10.2 0.1 2.2 2 2 0 2 2 2 0 GnsA/GnsB family ATP-synt_B PF00430.13 EAK88279.1 - 2.7 7.8 8.4 0.091 12.5 1.5 1.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Transformer PF06495.6 EAK88280.1 - 0.0012 18.7 24.7 0.0012 18.7 17.1 3.3 2 1 1 3 3 3 1 Fruit fly transformer protein Sigma_reg_N PF13800.1 EAK88284.1 - 5.1 7.1 7.1 13 5.9 4.9 1.8 1 1 0 1 1 1 0 Sigma factor regulator N-terminal DUF4407 PF14362.1 EAK88285.1 - 7.5 5.4 9.8 25 3.6 6.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Abhydrolase_2 PF02230.11 EAK88286.1 - 2.5e-32 112.1 0.0 4.5e-31 107.9 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EAK88286.1 - 8.8e-05 22.2 0.0 0.00016 21.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.2 EAK88287.1 - 4.9e-22 78.0 0.0 1.8e-10 40.9 0.1 5.2 3 1 3 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.25 EAK88287.1 - 2.2e-18 65.0 0.4 0.0009 18.9 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.1 EAK88287.1 - 2.9e-12 45.5 0.1 0.5 10.7 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 EAK88287.1 - 5.4e-12 45.5 0.9 0.011 15.9 0.0 6.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAK88287.1 - 3.3e-10 40.2 7.1 0.0083 16.6 0.0 7.5 7 1 2 9 9 9 4 Ankyrin repeats (many copies) SIS PF01380.17 EAK88288.1 - 3e-44 149.7 1.0 1.6e-23 82.7 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 EAK88288.1 - 1.8e-24 86.1 0.0 3.8e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EAK88288.1 - 2.3e-19 69.3 0.0 4.7e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EAK88288.1 - 2.3e-15 56.2 0.7 6.6e-13 48.0 0.0 2.5 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_4 PF13230.1 EAK88288.1 - 6.3e-05 21.7 0.1 0.00015 20.5 0.1 1.7 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EAK88288.1 - 0.0057 16.3 5.2 1.7 8.3 0.1 3.7 2 2 1 3 3 3 1 SIS domain bact-PGI_C PF10432.4 EAK88288.1 - 0.0058 16.3 0.0 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 Bacterial phospho-glucose isomerase C-terminal region AMP-binding PF00501.23 EAK88289.1 - 4.6e-92 308.5 0.0 6.1e-92 308.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAK88289.1 - 1.8e-18 67.2 0.0 7.6e-18 65.2 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 EAK88290.1 - 3.2e-41 137.7 11.6 8.6e-08 31.7 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EAK88290.1 - 7.2e-08 32.3 2.0 0.25 11.0 0.0 3.4 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EAK88290.1 - 0.019 13.1 4.4 0.37 8.8 0.6 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 SNF2_N PF00176.18 EAK88291.1 - 2.1e-70 236.9 0.4 3.5e-70 236.1 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EAK88291.1 - 5.7e-22 77.1 3.5 7.4e-10 38.3 0.2 3.6 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EAK88291.1 - 2.9e-15 55.8 0.0 9.2e-15 54.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 EAK88291.1 - 1e-10 41.7 0.3 1.1e-09 38.3 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) DEAD PF00270.24 EAK88291.1 - 6.7e-05 22.4 0.0 0.0054 16.2 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF3674 PF12426.3 EAK88292.1 - 0.017 14.5 0.7 0.057 12.8 0.5 1.9 1 0 0 1 1 1 0 RNA dependent RNA polymerase Patatin PF01734.17 EAK88293.1 - 1.8e-14 54.1 0.0 4.3e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase PITH PF06201.8 EAK88295.1 - 1.3e-37 128.8 0.1 1.6e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Transketolase_N PF00456.16 EAK88296.1 - 0.07 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DLIC PF05783.6 EAK88297.1 - 4.4e-06 25.6 15.6 0.00017 20.4 0.0 4.2 3 1 1 4 4 4 3 Dynein light intermediate chain (DLIC) PBS_linker_poly PF00427.16 EAK88297.1 - 0.044 13.4 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide TAFII55_N PF04658.8 EAK88298.1 - 9.6e-16 57.6 0.0 2.8e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 TAFII55 protein conserved region DUF1676 PF07898.8 EAK88299.1 - 0.0054 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) Reticulon PF02453.12 EAK88299.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Reticulon ABC2_membrane_3 PF12698.2 EAK88300.1 - 0.01 14.9 1.9 0.014 14.4 1.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein NUP PF06516.6 EAK88300.1 - 0.043 12.6 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) Vfa1 PF08432.5 EAK88300.1 - 0.43 10.5 3.9 0.63 10.0 2.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mucin PF01456.12 EAK88303.1 - 4.9e-05 23.1 45.8 0.0001 22.0 31.8 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein PAN_4 PF14295.1 EAK88303.1 - 0.015 14.9 2.5 0.05 13.3 1.7 2.0 1 0 0 1 1 1 0 PAN domain TEP1_N PF05386.6 EAK88303.1 - 0.11 12.0 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 TEP1 N-terminal domain DUF2201_N PF13203.1 EAK88303.1 - 0.14 11.3 0.4 0.21 10.7 0.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Glypican PF01153.14 EAK88303.1 - 1.8 7.0 12.3 0.76 8.3 6.9 1.5 1 1 0 1 1 1 0 Glypican AP2 PF00847.15 EAK88304.1 - 1.2e-10 41.4 3.7 2.2e-10 40.4 2.6 1.5 1 0 0 1 1 1 1 AP2 domain RRM_1 PF00076.17 EAK88305.1 - 2.6e-38 129.4 0.0 6.8e-18 64.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK88305.1 - 4.7e-29 100.1 0.0 2.1e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK88305.1 - 1.1e-13 50.7 0.0 7.7e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EAK88305.1 - 0.0001 21.9 0.2 0.036 13.8 0.0 2.4 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.6 EAK88305.1 - 0.022 14.6 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif TPR_11 PF13414.1 EAK88306.1 - 1.4e-12 47.0 13.3 0.0021 17.6 0.2 6.3 5 1 1 6 6 6 4 TPR repeat TPR_19 PF14559.1 EAK88306.1 - 7.2e-09 35.8 0.0 0.00089 19.5 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAK88306.1 - 6.5e-08 31.8 11.3 0.62 9.7 0.3 7.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAK88306.1 - 6.2e-07 29.9 0.0 0.041 14.5 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAK88306.1 - 9.8e-05 21.9 23.3 2.6 8.1 0.3 8.8 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAK88306.1 - 0.00011 22.4 0.1 1.6 9.5 0.0 5.6 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAK88306.1 - 0.00016 21.2 4.9 4.9 7.1 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAK88306.1 - 0.00023 21.0 13.7 8.7 6.3 0.0 7.8 6 3 1 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EAK88306.1 - 0.0011 19.0 15.8 0.11 12.6 0.0 5.5 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EAK88306.1 - 0.009 15.7 2.3 38 4.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat PCI PF01399.22 EAK88307.1 - 2.8e-10 40.4 0.9 9.9e-10 38.6 0.2 2.2 2 0 0 2 2 2 1 PCI domain Flu_NS1 PF00600.14 EAK88307.1 - 0.011 14.8 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) Sigma_reg_N PF13800.1 EAK88308.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal TSP_1 PF00090.14 EAK88309.1 - 7.3e-09 35.6 13.6 3.9e-07 30.0 2.6 6.1 7 1 0 7 7 7 4 Thrombospondin type 1 domain PAN_1 PF00024.21 EAK88309.1 - 7.9e-07 28.7 11.3 7e-05 22.5 2.1 3.9 4 1 1 5 5 5 2 PAN domain PAN_4 PF14295.1 EAK88309.1 - 0.00035 20.2 2.0 0.00035 20.2 1.4 4.4 4 0 0 4 4 4 2 PAN domain TSP_1 PF00090.14 EAK88310.1 - 4.6e-22 77.8 97.0 5.1e-09 36.0 8.8 8.3 8 1 0 8 8 8 6 Thrombospondin type 1 domain PAN_4 PF14295.1 EAK88310.1 - 0.00051 19.6 1.6 0.00051 19.6 1.1 6.4 8 1 0 8 8 8 1 PAN domain SKG6 PF08693.5 EAK88310.1 - 0.22 10.8 1.0 0.51 9.7 0.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Baculo_PEP_C PF04513.7 EAK88311.1 - 0.045 13.5 2.0 0.11 12.3 0.9 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TerY-C PF15616.1 EAK88311.1 - 0.073 13.0 4.4 0.055 13.4 2.0 1.6 1 1 0 1 1 1 0 TerY-C metal binding domain YmdB PF13277.1 EAK88311.1 - 0.088 11.8 0.8 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 YmdB-like protein RNase_T PF00929.19 EAK88311.1 - 0.21 11.8 4.2 1.4 9.1 0.3 2.1 1 1 1 2 2 2 0 Exonuclease Glyco_hydro_7 PF00840.15 EAK88311.1 - 0.29 9.4 0.9 0.38 9.0 0.6 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 Prominin PF05478.6 EAK88311.1 - 1.1 6.6 11.4 0.31 8.5 5.5 1.5 1 1 0 1 1 1 0 Prominin Allexi_40kDa PF05549.6 EAK88311.1 - 1.2 8.3 6.8 1.4 8.1 4.1 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein KfrA_N PF11740.3 EAK88311.1 - 1.3 9.4 6.5 0.44 11.0 1.8 1.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Hydantoinase_B PF02538.9 EAK88311.1 - 1.6 6.8 4.5 2.1 6.4 2.9 1.3 1 1 0 1 1 1 0 Hydantoinase B/oxoprolinase DUF1664 PF07889.7 EAK88311.1 - 2.1 8.1 10.5 0.28 10.9 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 EAK88311.1 - 3.6 7.1 26.1 0.093 12.2 12.2 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 EAK88311.1 - 4.5 6.1 21.7 5.6 5.8 15.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3332 PF11810.3 EAK88311.1 - 6.7 6.3 10.0 5.3 6.6 1.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3332) ATP-synt_B PF00430.13 EAK88311.1 - 7.8 6.3 22.5 1.6 8.5 1.7 2.5 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) ERCC4 PF02732.10 EAK88313.1 - 1.1e-21 77.0 0.3 4.7e-21 75.0 0.0 2.2 2 0 0 2 2 2 1 ERCC4 domain HHH_8 PF14716.1 EAK88313.1 - 0.00035 20.6 0.1 0.0051 16.9 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain Methyltransf_21 PF05050.7 EAK88314.1 - 3.7 7.4 9.2 0.15 12.0 1.9 2.0 2 1 0 2 2 2 0 Methyltransferase FkbM domain CS PF04969.11 EAK88315.1 - 0.00081 19.8 4.5 0.26 11.8 3.1 2.6 1 1 0 1 1 1 1 CS domain Apis_Csd PF11671.3 EAK88315.1 - 0.016 15.0 5.7 0.025 14.3 4.0 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein RC-P840_PscD PF10657.4 EAK88315.1 - 0.055 13.3 0.2 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD GPI2 PF06432.6 EAK88316.1 - 6.9e-44 150.2 20.1 2.6e-43 148.3 14.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Peptidase_M41 PF01434.13 EAK88317.1 - 5.5e-60 202.4 0.0 1.5e-59 201.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 EAK88317.1 - 7.6e-42 142.6 0.0 1.7e-41 141.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAK88317.1 - 4.4e-06 26.4 0.0 1.4e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EAK88317.1 - 4.4e-05 23.3 0.6 0.00051 19.9 0.0 3.1 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 EAK88317.1 - 4.9e-05 24.1 0.0 0.00021 22.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAK88317.1 - 0.00031 20.8 0.1 0.013 15.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EAK88317.1 - 0.0006 18.6 0.0 0.0015 17.2 0.0 1.7 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EAK88317.1 - 0.0014 17.6 0.0 0.0027 16.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAK88317.1 - 0.0033 17.1 0.9 0.0074 16.0 0.2 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA_16 PF13191.1 EAK88317.1 - 0.0042 17.0 0.1 0.014 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain FtsH_ext PF06480.10 EAK88317.1 - 0.0049 17.0 0.9 0.0049 17.0 0.6 3.4 3 1 0 3 3 3 1 FtsH Extracellular IstB_IS21 PF01695.12 EAK88317.1 - 0.0049 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EAK88317.1 - 0.01 15.7 0.0 0.029 14.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EAK88317.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAK88317.1 - 0.018 14.1 0.0 0.041 12.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 EAK88317.1 - 0.024 13.7 0.1 0.053 12.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EAK88317.1 - 0.034 13.5 0.9 0.11 11.8 0.2 1.9 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 EAK88317.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Myb_DNA-bind_6 PF13921.1 EAK88318.1 - 0.0027 17.7 0.0 0.0078 16.2 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-C3HC4 PF00097.20 EAK88319.1 - 4.1e-09 35.9 9.4 7.2e-09 35.1 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK88319.1 - 1.3e-07 31.4 9.5 2.3e-07 30.6 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAK88319.1 - 3.1e-05 23.6 6.9 5.4e-05 22.9 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EAK88319.1 - 3.7e-05 23.3 8.7 7.1e-05 22.4 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAK88319.1 - 8.5e-05 22.1 4.8 0.00017 21.1 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAK88319.1 - 0.00013 21.7 8.3 0.00026 20.7 5.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EAK88319.1 - 0.0016 18.2 3.4 0.0029 17.3 2.4 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 EAK88319.1 - 0.0017 17.8 5.7 0.0023 17.4 2.5 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EAK88319.1 - 0.44 10.3 6.9 1 9.1 4.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EAK88319.1 - 1.1 8.8 9.1 3.3 7.3 6.4 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 EAK88319.1 - 1.4 8.7 7.4 14 5.6 5.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) Cyclin_N PF00134.18 EAK88320.1 - 1.2e-08 34.5 0.5 2.5e-08 33.5 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain SusD-like_3 PF14322.1 EAK88320.1 - 0.16 12.0 3.0 4.2 7.3 0.2 2.8 2 1 1 3 3 3 0 Starch-binding associating with outer membrane MAT1 PF06391.8 EAK88321.1 - 2.2e-08 33.9 8.6 2.2e-08 33.9 6.0 1.7 1 1 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_3 PF13920.1 EAK88321.1 - 1.8e-05 24.3 4.7 5e-05 22.8 3.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAK88321.1 - 4e-05 23.1 13.0 0.00065 19.3 8.4 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK88321.1 - 9.7e-05 22.0 8.7 9.7e-05 22.0 6.0 2.5 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAK88321.1 - 0.00041 20.3 9.7 0.0006 19.7 5.5 2.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAK88321.1 - 0.00042 20.0 6.9 0.00042 20.0 4.8 2.3 3 1 1 4 4 2 1 Ring finger domain FYVE PF01363.16 EAK88321.1 - 0.00074 19.3 3.4 0.0021 17.9 2.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_4 PF14570.1 EAK88321.1 - 0.0044 16.5 6.1 0.015 14.8 4.2 1.9 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Ribosomal_L37ae PF01780.14 EAK88321.1 - 0.13 12.1 2.8 3.3 7.6 0.7 2.7 2 0 0 2 2 2 0 Ribosomal L37ae protein family zf-C3HC4_4 PF15227.1 EAK88321.1 - 0.27 11.1 13.2 0.78 9.6 4.1 3.4 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.9 EAK88321.1 - 0.69 9.4 6.8 4.4 6.8 0.3 3.8 3 1 0 3 3 3 0 Rad50 zinc hook motif Prim_Zn_Ribbon PF08273.7 EAK88321.1 - 1 9.5 7.2 0.74 9.9 1.7 2.4 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DZR PF12773.2 EAK88321.1 - 1.2 9.0 7.8 10 6.0 5.3 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 EAK88321.1 - 1.6 8.3 5.7 1.1 8.9 0.1 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Adaptin_binding PF10199.4 EAK88322.1 - 0.00089 19.5 10.4 0.0022 18.2 0.3 3.3 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 DHHA2 PF02833.9 EAK88322.1 - 0.024 14.8 0.3 0.19 11.9 0.0 2.3 2 1 1 3 3 3 0 DHHA2 domain DUF4611 PF15387.1 EAK88322.1 - 0.064 13.4 2.7 0.16 12.1 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Flu_B_M2 PF04772.7 EAK88322.1 - 0.21 11.6 2.9 0.81 9.7 0.2 2.7 3 0 0 3 3 3 0 Influenza B matrix protein 2 (BM2) DUF843 PF05814.6 EAK88324.1 - 0.19 11.5 2.9 0.18 11.6 0.5 1.9 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) DUF3661 PF12400.3 EAK88324.1 - 0.2 11.7 4.4 0.26 11.3 3.1 1.2 1 0 0 1 1 1 0 Vaculolar membrane protein EF-hand_7 PF13499.1 EAK88326.1 - 2e-12 47.0 0.9 6.6e-12 45.4 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EAK88326.1 - 1.4e-06 27.7 1.8 0.021 14.6 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EAK88326.1 - 1.8e-06 26.7 6.9 0.0082 15.3 0.0 3.6 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EAK88326.1 - 1.3e-05 24.7 0.2 0.0041 16.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EAK88326.1 - 0.016 14.5 2.2 0.13 11.6 0.0 3.0 3 0 0 3 3 3 0 EF hand Vma12 PF11712.3 EAK88328.1 - 7.7e-22 77.5 0.0 7.7e-22 77.5 0.0 2.6 2 1 1 3 3 3 1 Endoplasmic reticulum-based factor for assembly of V-ATPase TPR_19 PF14559.1 EAK88332.1 - 0.23 11.8 0.0 46 4.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Cyclin_N PF00134.18 EAK88333.1 - 2.1e-12 46.7 0.2 4.7e-12 45.5 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Sas10 PF09368.5 EAK88334.1 - 3.7e-24 84.6 10.2 3.7e-24 84.6 7.1 3.0 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EAK88334.1 - 3.7e-16 59.0 1.7 3.7e-16 59.0 1.2 4.1 4 1 1 5 5 5 1 Sas10/Utp3/C1D family Condensation PF00668.15 EAK88335.1 - 1.9e-11 43.3 0.0 8.2e-11 41.2 0.0 1.9 1 1 0 1 1 1 1 Condensation domain AATase PF07247.7 EAK88335.1 - 2e-07 29.9 1.2 8.2e-06 24.6 0.1 3.2 2 1 0 2 2 2 1 Alcohol acetyltransferase Spc97_Spc98 PF04130.8 EAK88336.1 - 9.7e-10 37.3 6.4 9.7e-10 37.3 4.5 2.7 4 1 0 4 4 4 1 Spc97 / Spc98 family PAN_3 PF08277.7 EAK88336.1 - 0.0094 15.5 0.3 0.031 13.8 0.2 1.9 1 0 0 1 1 1 1 PAN-like domain Phage_RpbA PF10789.4 EAK88336.1 - 0.037 13.8 0.2 0.9 9.4 0.0 2.7 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA Polysacc_deac_1 PF01522.16 EAK88340.1 - 5.2e-13 48.7 0.0 2.7e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide deacetylase zf-RING_UBOX PF13445.1 EAK88340.1 - 0.3 10.8 2.1 1.6 8.5 0.0 2.8 3 0 0 3 3 3 0 RING-type zinc-finger DUF2051 PF09738.4 EAK88340.1 - 9.9 5.3 9.3 17 4.5 6.4 1.4 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Cation_efflux PF01545.16 EAK88341.1 - 2.8e-65 220.2 6.3 4.6e-65 219.5 4.4 1.3 1 1 0 1 1 1 1 Cation efflux family DUF1282 PF06930.7 EAK88341.1 - 0.47 10.1 8.5 0.18 11.4 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) TIM PF00121.13 EAK88342.1 - 6.5e-87 290.6 0.0 7.4e-87 290.4 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase WD40 PF00400.27 EAK88343.1 - 6.9e-06 25.7 7.3 0.06 13.2 0.3 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ER_lumen_recept PF00810.13 EAK88344.1 - 1.7e-42 145.3 6.6 1.7e-42 145.3 4.6 2.1 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EAK88344.1 - 0.075 12.5 0.1 0.075 12.5 0.1 3.7 3 1 1 4 4 4 0 PQ loop repeat CGI-121 PF08617.5 EAK88345.1 - 1.1e-07 31.6 0.2 1.5e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DnaJ PF00226.26 EAK88346.1 - 5.1e-10 38.9 1.4 1e-09 37.9 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain GET2 PF08690.5 EAK88346.1 - 0.083 12.1 3.3 0.25 10.5 2.2 1.8 2 0 0 2 2 2 0 GET complex subunit GET2 DUF2465 PF10239.4 EAK88346.1 - 0.11 11.7 1.4 0.87 8.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2465) DUF2263 PF10021.4 EAK88346.1 - 0.47 10.4 2.7 0.49 10.3 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2263) V-SNARE_C PF12352.3 EAK88348.1 - 9.2e-11 41.6 2.6 9.2e-11 41.6 1.8 2.9 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EAK88348.1 - 0.00057 19.5 0.3 0.00057 19.5 0.2 2.6 2 1 0 2 2 2 1 Sec20 Allexi_40kDa PF05549.6 EAK88348.1 - 0.013 14.7 1.1 0.019 14.3 0.8 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein ASD1 PF08688.5 EAK88348.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.4 1 1 0 1 1 1 0 Apx/Shroom domain ASD1 Exonuc_VII_S PF02609.11 EAK88348.1 - 0.085 12.6 2.2 1.2 8.9 0.2 3.1 3 1 0 3 3 3 0 Exonuclease VII small subunit BRE1 PF08647.6 EAK88348.1 - 0.092 12.7 7.4 0.036 14.0 2.6 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase SCP-1 PF05483.7 EAK88348.1 - 0.12 10.1 9.0 0.043 11.6 3.8 1.7 1 1 1 2 2 2 0 Synaptonemal complex protein 1 (SCP-1) V-SNARE PF05008.10 EAK88348.1 - 2.9 8.1 10.6 1.6 8.9 0.6 3.4 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Sec2p PF06428.6 EAK88348.1 - 4 7.3 8.8 0.72 9.7 0.8 2.7 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Utp21 PF04192.7 EAK88349.1 - 1.6e-40 138.7 3.0 2.7e-40 137.9 2.1 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EAK88349.1 - 1.3e-07 31.1 7.5 0.018 14.9 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Hira PF07569.6 EAK88349.1 - 0.0024 17.1 0.4 0.0024 17.1 0.3 3.1 4 0 0 4 4 4 1 TUP1-like enhancer of split YccV-like PF08755.6 EAK88351.1 - 2.7e-27 94.6 0.4 2.7e-27 94.6 0.3 2.2 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like PRKCSH PF07915.8 EAK88351.1 - 7.1e-09 36.3 1.5 2.6e-08 34.5 0.0 2.8 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EAK88351.1 - 0.0017 17.8 0.1 0.0064 15.9 0.0 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein RRM_1 PF00076.17 EAK88352.1 - 1.1e-48 162.7 0.0 8.5e-22 76.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK88352.1 - 1.1e-33 115.0 0.0 6.8e-15 54.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK88352.1 - 2.5e-30 104.0 0.1 3.3e-10 39.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAK88352.1 - 0.00076 19.1 0.1 0.0093 15.7 0.0 2.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Med7 PF05983.6 EAK88353.1 - 1.4e-32 112.7 1.4 1.6e-32 112.5 1.0 1.0 1 0 0 1 1 1 1 MED7 protein Sec2p PF06428.6 EAK88353.1 - 0.0055 16.5 1.4 0.0095 15.7 1.0 1.4 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p DUF641 PF04859.7 EAK88353.1 - 0.011 15.4 1.4 0.014 15.1 1.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) BCDHK_Adom3 PF10436.4 EAK88353.1 - 0.039 13.4 0.9 0.054 13.0 0.6 1.1 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Glutaredoxin2_C PF04399.8 EAK88353.1 - 0.071 12.6 1.6 0.1 12.1 0.8 1.5 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain Med4 PF10018.4 EAK88353.1 - 0.071 12.5 5.1 0.088 12.1 3.5 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 SRP1_TIP1 PF00660.12 EAK88353.1 - 0.099 12.4 1.7 0.68 9.7 0.2 2.2 2 0 0 2 2 2 0 Seripauperin and TIP1 family Med2 PF11214.3 EAK88353.1 - 0.1 12.6 3.9 0.21 11.6 2.7 1.6 1 1 0 1 1 1 0 Mediator complex subunit 2 SlyX PF04102.7 EAK88353.1 - 0.16 12.3 1.8 0.39 11.1 1.2 1.8 1 0 0 1 1 1 0 SlyX Cep57_CLD_2 PF14197.1 EAK88353.1 - 0.16 11.9 4.2 0.28 11.1 2.9 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF745 PF05335.8 EAK88353.1 - 0.22 11.0 1.1 0.27 10.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) V-SNARE PF05008.10 EAK88353.1 - 0.29 11.3 3.5 0.73 10.0 2.4 1.7 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Ly49 PF08391.5 EAK88353.1 - 0.55 10.3 4.6 1 9.5 3.2 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region RNA_pol_Rpb2_6 PF00562.23 EAK88354.1 - 1.9e-119 398.8 0.0 2.5e-119 398.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EAK88354.1 - 1.9e-35 121.6 0.0 3e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EAK88354.1 - 1.9e-22 78.7 0.0 3.7e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 EAK88354.1 - 7.7e-18 64.5 0.0 2.1e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 EAK88354.1 - 3.2e-10 39.7 0.0 8.1e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain BRE PF06113.7 EAK88354.1 - 0.01 14.8 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) AAA PF00004.24 EAK88355.1 - 2.8e-10 40.4 0.5 1.8e-09 37.8 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAK88355.1 - 0.001 19.0 1.3 0.11 12.5 0.1 3.9 3 1 0 4 4 4 1 AAA ATPase domain DUF815 PF05673.8 EAK88355.1 - 0.0035 16.2 0.0 0.04 12.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 EAK88355.1 - 0.0084 15.6 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EAK88355.1 - 0.011 15.9 0.5 2.2 8.4 0.1 3.4 2 1 1 3 3 3 0 AAA domain AAA_10 PF12846.2 EAK88355.1 - 0.018 14.5 0.9 0.14 11.6 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 EAK88355.1 - 0.052 13.7 0.0 0.56 10.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 EAK88355.1 - 0.055 13.3 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2554 PF10829.3 EAK88355.1 - 0.06 13.4 0.0 0.18 11.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2554) NACHT PF05729.7 EAK88355.1 - 0.11 12.1 0.2 1.2 8.7 0.0 2.6 2 1 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 EAK88355.1 - 0.15 12.3 0.1 0.15 12.3 0.0 2.5 3 1 0 3 3 3 0 ABC transporter Zw10 PF06248.8 EAK88356.1 - 4e-27 94.6 10.8 1.8e-26 92.5 7.3 2.1 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Peptidase_M24 PF00557.19 EAK88357.1 - 9.4e-46 156.0 0.0 1.5e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EAK88357.1 - 0.00015 21.6 6.5 0.00015 21.6 4.5 1.8 2 0 0 2 2 2 1 MYND finger RasGEF_N_2 PF14663.1 EAK88357.1 - 0.11 12.4 0.0 6.6 6.7 0.0 2.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Clr5 PF14420.1 EAK88357.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Clr5 domain Peptidase_M2 PF01401.13 EAK88357.1 - 0.16 10.1 0.0 0.25 9.5 0.0 1.1 1 0 0 1 1 1 0 Angiotensin-converting enzyme RNA_pol_A_bac PF01000.21 EAK88359.1 - 1.4e-26 92.8 0.0 2.6e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EAK88359.1 - 1.4e-16 59.3 0.0 1.9e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Na_Ca_ex PF01699.19 EAK88360.1 - 2.2e-42 143.9 34.9 4.9e-24 84.5 10.1 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein WD40 PF00400.27 EAK88361.1 - 2.5e-20 71.5 22.6 3.6e-08 32.9 0.4 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EAK88361.1 - 8.9e-16 58.2 3.1 8.9e-16 58.2 2.2 2.2 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit Abhydrolase_5 PF12695.2 EAK88362.1 - 2.3e-14 53.3 0.0 3.8e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAK88362.1 - 0.00029 20.7 0.0 0.0055 16.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Arf PF00025.16 EAK88363.1 - 2.8e-16 59.2 0.0 1.6e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.5 EAK88363.1 - 4.6e-05 22.6 0.5 0.0042 16.3 0.4 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EAK88363.1 - 0.0048 16.3 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EAK88363.1 - 0.0096 16.4 0.0 0.1 13.1 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EAK88363.1 - 0.038 12.6 0.1 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit T2SE PF00437.15 EAK88363.1 - 0.065 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein zinc_ribbon_6 PF14599.1 EAK88364.1 - 1.1e-18 66.7 0.8 1.1e-18 66.7 0.5 4.3 3 2 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 EAK88364.1 - 4e-16 58.9 25.6 4e-16 58.9 17.8 4.8 2 2 1 3 3 3 1 CHY zinc finger zf-C3HC4_2 PF13923.1 EAK88364.1 - 8.1e-06 25.7 3.6 8.1e-06 25.7 2.5 6.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAK88364.1 - 0.019 14.8 3.1 0.019 14.8 2.2 6.5 3 2 4 7 7 7 0 zinc finger of C3HC4-type, RING Porin_3 PF01459.17 EAK88365.1 - 1.6e-28 99.7 1.0 2e-28 99.4 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin Ctr PF04145.10 EAK88366.1 - 2.6e-25 89.1 21.0 9.9e-15 54.8 0.9 2.1 1 1 1 2 2 2 2 Ctr copper transporter family H_PPase PF03030.11 EAK88366.1 - 0.0019 16.5 3.4 0.0023 16.2 2.3 1.1 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF3816 PF12822.2 EAK88366.1 - 0.064 13.1 6.7 0.087 12.7 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) DUF3278 PF11683.3 EAK88366.1 - 0.084 12.8 6.9 0.064 13.2 4.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) DUF4064 PF13273.1 EAK88366.1 - 0.17 12.0 6.6 0.46 10.6 4.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) SPC25 PF06703.6 EAK88366.1 - 6.5 6.3 6.3 1.7 8.2 0.1 2.0 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Filamin PF00630.14 EAK88367.1 - 2.8e-20 72.7 2.2 4.3e-13 49.7 0.1 3.4 3 0 0 3 3 3 2 Filamin/ABP280 repeat Radical_SAM PF04055.16 EAK88373.1 - 2.6e-09 37.4 8.1 3.1e-09 37.2 2.7 3.1 3 1 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EAK88373.1 - 0.00051 20.0 0.0 0.0023 17.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family O-FucT PF10250.4 EAK88374.1 - 1e-64 218.8 2.8 1.3e-64 218.5 2.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Actin PF00022.14 EAK88375.1 - 9.7e-22 76.9 0.0 9.4e-19 67.0 0.0 2.3 1 1 1 2 2 2 2 Actin Myb_DNA-binding PF00249.26 EAK88378.1 - 0.00032 20.7 0.0 0.00053 19.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rad1 PF02144.11 EAK88380.1 - 1.5e-06 27.1 2.7 8.9e-06 24.6 1.9 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EAK88380.1 - 0.0019 17.3 0.4 0.0023 17.1 0.3 1.2 1 0 0 1 1 1 1 Rad9 Cyclin_N PF00134.18 EAK88381.1 - 5.3e-15 55.1 0.1 4e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EAK88381.1 - 3.5e-12 46.3 0.1 8e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain FliM PF02154.10 EAK88381.1 - 0.0054 16.4 0.2 2.7 7.6 0.0 2.5 2 1 0 2 2 2 2 Flagellar motor switch protein FliM Recep_L_domain PF01030.19 EAK88381.1 - 0.061 13.3 1.0 1.1 9.2 0.4 2.5 2 0 0 2 2 2 0 Receptor L domain Ribosomal_S26e PF01283.14 EAK88382.1 - 3.8e-48 162.4 12.0 4.1e-48 162.3 8.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e SRP19 PF01922.12 EAK88382.1 - 0.06 13.9 0.1 0.09 13.3 0.1 1.4 1 0 0 1 1 1 0 SRP19 protein RNA_pol_Rpb8 PF03870.10 EAK88383.1 - 2.8e-35 121.4 0.1 3.2e-35 121.3 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 DEK_C PF08766.6 EAK88384.1 - 1.4e-15 56.8 2.7 2.6e-15 55.9 0.3 2.1 2 0 0 2 2 2 1 DEK C terminal domain ATP-cone PF03477.11 EAK88384.1 - 0.014 15.7 0.4 0.046 14.1 0.1 1.9 1 1 0 1 1 1 0 ATP cone domain Troponin PF00992.15 EAK88384.1 - 0.068 13.2 2.3 0.095 12.7 1.2 1.6 1 1 0 1 1 1 0 Troponin CENP-P PF13096.1 EAK88384.1 - 0.1 11.9 0.4 0.18 11.1 0.3 1.3 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P FANCI_S3 PF14677.1 EAK88384.1 - 0.59 9.4 3.3 0.3 10.4 0.4 1.8 1 1 1 2 2 2 0 FANCI solenoid 3 FlaF PF07309.6 EAK88385.1 - 0.0021 17.9 0.2 0.0029 17.4 0.1 1.2 1 0 0 1 1 1 1 Flagellar protein FlaF CTK3 PF12243.3 EAK88385.1 - 0.055 13.1 0.1 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 DUF972 PF06156.8 EAK88385.1 - 0.059 13.7 1.4 0.081 13.2 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Pox_polyA_pol_N PF12630.2 EAK88385.1 - 4.3 7.4 6.1 16 5.6 0.2 2.1 1 1 1 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain Phage_Orf51 PF06194.6 EAK88386.1 - 0.016 15.2 3.2 7.1 6.8 0.1 4.4 4 1 1 5 5 5 0 Phage Conserved Open Reading Frame 51 Rnk_N PF14760.1 EAK88386.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Rnk N-terminus Na_H_Exchanger PF00999.16 EAK88387.1 - 9.1e-54 182.4 56.3 1.4e-53 181.7 39.0 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TIG PF01833.19 EAK88387.1 - 2.3e-07 30.7 6.6 0.0055 16.6 0.6 4.0 2 1 0 2 2 2 2 IPT/TIG domain DUF4144 PF13642.1 EAK88387.1 - 0.025 14.8 0.9 3 8.2 0.0 3.0 2 0 0 2 2 2 0 protein structure with unknown function AAA PF00004.24 EAK88388.1 - 2.3e-35 121.6 1.3 1.3e-34 119.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAK88388.1 - 2.8e-07 29.8 0.0 6.5e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EAK88388.1 - 1.2e-05 26.0 1.0 0.00011 23.0 0.0 2.9 2 2 1 3 3 2 1 AAA domain AAA_14 PF13173.1 EAK88388.1 - 1.6e-05 24.7 1.3 0.00013 21.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAK88388.1 - 2.1e-05 24.6 1.7 0.064 13.4 0.0 3.8 2 1 1 4 4 4 1 AAA domain AAA_2 PF07724.9 EAK88388.1 - 5.8e-05 23.0 0.1 0.00044 20.2 0.0 2.2 1 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EAK88388.1 - 0.00015 21.4 0.0 0.00055 19.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EAK88388.1 - 0.00088 18.9 0.1 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAK88388.1 - 0.00094 19.4 2.3 0.0057 16.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAK88388.1 - 0.0023 17.6 0.0 0.005 16.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EAK88388.1 - 0.0044 16.8 0.0 0.013 15.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EAK88388.1 - 0.0082 16.3 0.0 0.028 14.6 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EAK88388.1 - 0.012 15.6 0.0 0.11 12.4 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain NACHT PF05729.7 EAK88388.1 - 0.02 14.5 2.4 2 8.0 0.0 2.8 2 1 1 3 3 3 0 NACHT domain Zeta_toxin PF06414.7 EAK88388.1 - 0.023 13.8 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin HTH_38 PF13936.1 EAK88388.1 - 0.039 13.4 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain SET PF00856.23 EAK88389.1 - 2.9e-12 47.1 0.5 3.4e-12 46.9 0.3 1.6 1 1 0 1 1 1 1 SET domain Kp4 PF09044.5 EAK88389.1 - 0.016 15.0 0.8 0.032 14.0 0.6 1.5 1 0 0 1 1 1 0 Kp4 GYF PF02213.11 EAK88390.1 - 2.7e-06 26.8 0.0 2.9e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 GYF domain BTB PF00651.26 EAK88390.1 - 0.0013 18.7 0.1 0.0073 16.2 0.0 2.2 1 1 0 2 2 2 1 BTB/POZ domain GYF PF02213.11 EAK88391.1 - 7e-08 31.9 0.0 1.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 GYF domain BTB PF00651.26 EAK88391.1 - 0.00048 20.0 0.3 0.0036 17.2 0.0 2.5 2 1 0 2 2 2 1 BTB/POZ domain tRNA-synt_1c PF00749.16 EAK88392.1 - 1.5e-95 319.4 1.0 1.9e-95 319.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EAK88392.1 - 1.2e-35 122.7 0.7 2.5e-35 121.7 0.5 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain PI31_Prot_N PF11566.3 EAK88393.1 - 0.0021 17.6 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal HEAT PF02985.17 EAK88394.1 - 2.5e-10 39.5 7.6 0.87 9.8 0.0 8.7 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.1 EAK88394.1 - 2e-07 31.2 0.0 0.018 15.3 0.0 4.5 5 0 0 5 5 5 2 HEAT repeats Poxvirus_B22R_C PF13168.1 EAK88394.1 - 0.0072 15.6 0.0 0.035 13.3 0.0 2.3 2 0 0 2 2 2 1 Poxvirus B22R protein C-terminal DUF2411 PF10304.4 EAK88394.1 - 0.026 14.0 3.7 0.12 11.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2411) HEAT_EZ PF13513.1 EAK88394.1 - 0.077 13.5 0.0 0.35 11.4 0.0 2.3 1 0 0 1 1 1 0 HEAT-like repeat DUF2392 PF10288.4 EAK88395.1 - 2.2e-05 24.7 0.3 5.5e-05 23.4 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) DZR PF12773.2 EAK88395.1 - 0.36 10.6 6.3 6.7 6.6 0.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon Cytochrom_c3_2 PF14537.1 EAK88395.1 - 1.5 9.2 5.4 7.5 6.9 1.5 2.4 2 0 0 2 2 2 0 Cytochrome c3 PWWP PF00855.12 EAK88397.1 - 0.013 15.6 0.1 0.16 12.1 0.0 2.6 1 1 1 2 2 2 0 PWWP domain Mog1 PF04603.7 EAK88398.1 - 5.3e-23 81.5 0.0 7e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein DUF202 PF02656.10 EAK88399.1 - 0.31 11.2 8.0 0.62 10.3 0.7 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF202) TRIQK PF15168.1 EAK88399.1 - 0.34 10.8 6.7 7.2 6.6 0.4 3.2 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family DUF2721 PF11026.3 EAK88399.1 - 0.39 10.3 6.5 0.3 10.7 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Claudin_2 PF13903.1 EAK88399.1 - 1.5 8.4 13.4 2 8.0 9.0 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TauE PF01925.14 EAK88400.1 - 1.5e-21 76.9 12.7 8.8e-11 41.7 3.3 2.4 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DUF2937 PF11157.3 EAK88400.1 - 0.41 9.9 0.0 0.41 9.9 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2937) DUF1356 PF07092.7 EAK88400.1 - 5.6 6.0 11.5 0.18 10.9 0.5 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1356) ApoLp-III PF07464.6 EAK88402.1 - 0.28 11.1 14.0 1 9.3 0.4 3.5 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) COPI_assoc PF08507.5 EAK88403.1 - 1.1e-07 31.5 5.3 1.5e-07 31.1 3.7 1.1 1 0 0 1 1 1 1 COPI associated protein Prenyltrans PF00432.16 EAK88404.1 - 2.2e-34 116.6 12.3 9.6e-11 41.0 2.3 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EAK88404.1 - 4.8e-19 68.8 0.0 2.6e-07 31.0 0.0 3.9 3 1 1 4 4 4 3 Prenyltransferase-like DUF2093 PF09866.4 EAK88404.1 - 0.47 9.6 6.0 0.57 9.4 2.0 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) Utp14 PF04615.8 EAK88405.1 - 3e-47 161.2 55.6 2.5e-26 92.1 32.0 2.5 1 1 1 2 2 2 2 Utp14 protein KH_5 PF13184.1 EAK88405.1 - 0.044 13.5 2.2 0.18 11.6 0.1 2.8 2 0 0 2 2 2 0 NusA-like KH domain Sec20 PF03908.8 EAK88405.1 - 0.21 11.3 8.0 6.2 6.6 1.0 3.6 2 1 0 2 2 2 0 Sec20 HECT PF00632.20 EAK88406.1 - 7.2e-66 222.4 1.5 7.2e-66 222.4 1.0 4.1 6 0 0 6 6 6 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 EAK88406.1 - 1.1e-08 35.2 0.7 3.9e-08 33.4 0.5 2.0 1 0 0 1 1 1 1 SPRY domain Laminin_G_3 PF13385.1 EAK88406.1 - 0.0002 21.6 0.1 0.00062 20.0 0.1 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily UBA PF00627.26 EAK88406.1 - 0.00091 18.9 0.1 0.0027 17.4 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.26 EAK88407.1 - 4.1e-10 39.2 0.1 1.2e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain UPRTase PF14681.1 EAK88408.1 - 7.5e-59 198.4 0.0 9.2e-59 198.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EAK88408.1 - 6.8e-05 22.5 0.0 0.00019 21.1 0.0 1.8 2 1 0 2 2 2 1 Phosphoribosyl transferase domain IF-2B PF01008.12 EAK88410.1 - 2.3e-18 66.1 6.9 3.3e-17 62.3 4.8 2.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF4298 PF14131.1 EAK88410.1 - 0.021 14.7 0.1 0.089 12.6 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4298) GSH-S_ATP PF02955.11 EAK88411.1 - 0.02 14.0 1.2 0.18 10.9 0.0 2.5 2 1 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain G-patch PF01585.18 EAK88412.1 - 2e-15 56.2 2.0 3.5e-15 55.5 1.4 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EAK88412.1 - 1.3e-05 24.9 0.1 2.2e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 DExH-box splicing factor binding site TB2_DP1_HVA22 PF03134.14 EAK88414.1 - 1.6e-35 120.7 7.6 1.6e-35 120.7 5.3 1.6 1 1 1 2 2 2 1 TB2/DP1, HVA22 family DUF3816 PF12822.2 EAK88414.1 - 0.0015 18.4 0.9 0.0023 17.8 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3816) YvrJ PF12841.2 EAK88414.1 - 0.081 12.2 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 YvrJ protein family DUF1077 PF06417.7 EAK88414.1 - 0.12 11.6 0.5 0.21 10.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) EBP PF05241.7 EAK88414.1 - 4.5 6.2 10.2 1.5 7.8 4.9 1.7 1 1 1 2 2 2 0 Emopamil binding protein CAF1A PF12253.3 EAK88415.1 - 5.3e-09 36.0 3.5 1.9e-08 34.2 2.4 2.0 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A zf-RING_2 PF13639.1 EAK88417.1 - 3.4e-09 36.3 12.4 6.4e-09 35.5 8.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAK88417.1 - 2.9e-07 30.4 9.5 6.4e-07 29.3 6.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EAK88417.1 - 2.4e-06 27.1 10.8 4.4e-06 26.2 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK88417.1 - 4.2e-05 23.1 11.4 7.8e-05 22.3 7.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAK88417.1 - 0.00018 21.4 13.6 0.00039 20.3 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EAK88417.1 - 0.0031 17.3 5.4 0.008 16.0 3.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EAK88417.1 - 0.0046 16.5 11.6 0.013 15.1 8.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF4206 PF13901.1 EAK88417.1 - 0.0066 16.0 8.0 0.013 15.1 5.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) FANCL_C PF11793.3 EAK88417.1 - 0.8 9.7 9.6 2.8 7.9 6.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EAK88417.1 - 4.6 7.3 11.7 9.3 6.3 8.1 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 EAK88417.1 - 6 6.6 11.4 11 5.8 7.9 1.5 1 0 0 1 1 1 0 PHD-finger CDC50 PF03381.10 EAK88419.1 - 2.3e-28 99.1 9.9 2.3e-28 99.1 6.9 2.5 1 1 1 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4064 PF13273.1 EAK88419.1 - 0.036 14.1 1.1 0.22 11.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DDRGK PF09756.4 EAK88421.1 - 2.4e-50 170.5 18.6 3.4e-50 170.0 12.9 1.2 1 0 0 1 1 1 1 DDRGK domain HTH_24 PF13412.1 EAK88421.1 - 0.0032 16.8 0.6 0.016 14.6 0.3 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding ENT PF03735.9 EAK88421.1 - 0.068 12.9 0.2 0.068 12.9 0.1 2.6 3 0 0 3 3 3 0 ENT domain Hydrolase_3 PF08282.7 EAK88422.1 - 5.1e-30 104.8 0.0 1.4e-28 100.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EAK88422.1 - 1.1e-06 28.1 0.0 2.5e-05 23.7 0.0 2.4 2 1 1 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EAK88422.1 - 0.044 14.2 0.0 0.077 13.4 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SpoU_methylase PF00588.14 EAK88423.1 - 8.8e-26 90.4 0.0 1.9e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF2009 PF09418.5 EAK88424.1 - 8.6e-181 601.6 5.0 6.6e-120 400.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2009) His_Phos_1 PF00300.17 EAK88425.1 - 6.6e-18 65.2 0.0 7.6e-16 58.6 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EAK88425.1 - 0.0057 16.0 0.1 0.0077 15.6 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GATA PF00320.22 EAK88426.1 - 7.4e-07 28.4 4.9 7.4e-07 28.4 3.4 2.3 2 0 0 2 2 2 1 GATA zinc finger PHD PF00628.24 EAK88427.1 - 0.00043 19.9 10.2 0.0013 18.3 7.1 1.9 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EAK88427.1 - 0.0023 18.0 3.7 0.0023 18.0 2.6 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain PWWP PF00855.12 EAK88427.1 - 0.15 12.2 4.9 0.057 13.6 0.6 2.6 2 1 0 2 2 2 0 PWWP domain Prok-RING_1 PF14446.1 EAK88427.1 - 0.31 10.8 12.1 0.039 13.6 4.5 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 C1_3 PF07649.7 EAK88427.1 - 0.46 10.5 5.2 2.2 8.4 3.6 2.2 1 0 0 1 1 1 0 C1-like domain HypA PF01155.14 EAK88427.1 - 0.57 9.8 4.5 1.8 8.2 1.0 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family PHD_2 PF13831.1 EAK88427.1 - 8.8 5.7 10.9 2.2 7.6 3.3 2.4 2 0 0 2 2 2 0 PHD-finger DZR PF12773.2 EAK88427.1 - 9.4 6.1 10.2 6.8 6.5 4.5 2.6 2 1 0 2 2 2 0 Double zinc ribbon Ribosomal_L36e PF01158.13 EAK88428.1 - 5.2e-39 132.1 3.0 5.9e-39 131.9 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Bystin PF05291.6 EAK88429.1 - 4e-103 344.5 6.8 6.4e-103 343.8 4.7 1.2 1 0 0 1 1 1 1 Bystin DUF383 PF04063.9 EAK88430.1 - 0.0038 16.8 0.1 0.0047 16.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF681 PF05080.7 EAK88430.1 - 0.032 14.6 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF681) PLU-1 PF08429.6 EAK88431.1 - 2.7e-53 181.0 48.5 1.8e-47 161.8 7.9 8.7 7 2 0 8 8 8 6 PLU-1-like protein PHD PF00628.24 EAK88431.1 - 1.4e-07 31.0 7.6 4.6e-07 29.4 5.3 2.0 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EAK88431.1 - 0.028 14.1 0.3 0.12 12.1 0.2 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 EAK88431.1 - 1.9 8.4 6.1 5.7 6.8 4.2 1.9 1 0 0 1 1 1 0 Ring finger domain SHS2_Rpb7-N PF03876.12 EAK88434.1 - 2.7e-08 33.7 0.1 7.2e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pet127 PF08634.5 EAK88434.1 - 0.015 14.4 0.4 0.26 10.3 0.1 2.4 1 1 1 2 2 2 0 Mitochondrial protein Pet127 PAZ PF02170.17 EAK88435.1 - 0.0077 15.5 0.4 0.013 14.8 0.3 1.4 1 0 0 1 1 1 1 PAZ domain E2F_TDP PF02319.15 EAK88437.1 - 1.1e-13 50.5 0.0 2.3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 EAK88437.1 - 0.019 14.6 0.1 0.084 12.5 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB PCI PF01399.22 EAK88438.1 - 5.7e-10 39.4 2.3 5.7e-10 39.4 1.6 3.2 3 1 0 3 3 3 1 PCI domain WD40 PF00400.27 EAK88439.1 - 2.7e-14 52.4 9.2 1.5e-05 24.6 0.4 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat GCC2_GCC3 PF07699.8 EAK88440.1 - 6.9e-09 35.1 31.9 3.8e-07 29.5 7.0 4.0 3 1 1 4 4 4 2 GCC2 and GCC3 PMT_2 PF13231.1 EAK88441.1 - 0.019 14.8 9.6 0.58 10.0 4.3 2.2 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase E1-E2_ATPase PF00122.15 EAK88441.1 - 0.078 12.0 3.1 0.048 12.6 0.6 1.6 2 0 0 2 2 2 0 E1-E2 ATPase ATP-synt_D PF01813.12 EAK88442.1 - 0.52 9.8 11.7 1.9 7.9 1.6 2.5 3 0 0 3 3 3 0 ATP synthase subunit D DUF1664 PF07889.7 EAK88442.1 - 0.68 9.7 7.8 22 4.8 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2216 PF10226.4 EAK88442.1 - 0.99 8.8 7.3 4 6.9 3.7 2.4 2 1 0 2 2 2 0 Uncharacterized conserved proteins (DUF2216) Snapin_Pallidin PF14712.1 EAK88442.1 - 5.1 7.4 13.3 0.89 9.9 0.9 3.4 3 1 0 3 3 3 0 Snapin/Pallidin BRICHOS PF04089.9 EAK88445.1 - 0.034 14.0 0.4 0.16 11.8 0.3 2.2 1 0 0 1 1 1 0 BRICHOS domain zf-DHHC PF01529.15 EAK88452.1 - 8.5e-44 149.0 6.9 8.5e-44 149.0 4.8 2.2 1 1 1 2 2 2 2 DHHC palmitoyltransferase MgtE PF01769.11 EAK88452.1 - 1.6 8.9 8.8 1.2 9.3 0.9 2.7 2 1 0 2 2 2 0 Divalent cation transporter DUF2439 PF10382.4 EAK88453.1 - 3.3e-19 68.8 1.3 6.3e-19 67.9 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) PH PF00169.24 EAK88453.1 - 0.07 13.3 0.1 0.14 12.3 0.1 1.7 1 1 0 1 1 1 0 PH domain ABC_tran PF00005.22 EAK88454.1 - 2.2e-30 105.7 0.1 7.9e-30 103.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EAK88454.1 - 2e-23 83.1 17.6 3e-23 82.6 12.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EAK88454.1 - 3.3e-05 23.2 0.0 0.00012 21.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NB-ARC PF00931.17 EAK88454.1 - 0.0057 15.5 0.0 0.044 12.6 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_17 PF13207.1 EAK88454.1 - 0.0057 17.4 0.0 0.018 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EAK88454.1 - 0.015 15.0 0.1 0.1 12.3 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EAK88454.1 - 0.039 14.2 0.3 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EAK88454.1 - 0.041 13.3 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EAK88454.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EAK88454.1 - 0.13 12.1 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Glyco_transf_41 PF13844.1 EAK88456.1 - 1.5e-39 135.2 0.4 1e-21 76.4 0.0 3.4 3 1 0 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EAK88456.1 - 1.5e-19 69.4 0.9 7.3e-06 25.5 0.0 4.7 3 1 2 5 5 5 4 TPR repeat TPR_1 PF00515.23 EAK88456.1 - 3.5e-19 67.5 3.5 2.6e-05 23.6 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EAK88456.1 - 2.1e-17 61.5 0.1 2.4e-05 23.9 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EAK88456.1 - 2.6e-16 58.1 7.4 0.0021 17.6 0.0 6.7 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EAK88456.1 - 1.4e-15 56.0 3.6 0.001 19.1 0.0 6.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EAK88456.1 - 3e-13 49.5 0.2 6.6e-06 25.9 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EAK88456.1 - 3.8e-08 32.5 0.0 0.27 11.1 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAK88456.1 - 3.3e-06 27.3 0.0 0.55 10.6 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAK88456.1 - 5.4e-05 23.4 0.0 18 6.3 0.0 5.3 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EAK88456.1 - 0.00018 21.3 0.0 22 5.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAK88456.1 - 0.0018 18.5 0.0 6.3 7.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAK88456.1 - 0.013 16.1 0.0 38 5.1 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EAK88456.1 - 0.063 13.1 0.0 5.1 7.0 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat KH_1 PF00013.24 EAK88458.1 - 7e-27 92.8 2.9 1.1e-07 31.4 0.0 4.8 5 0 0 5 5 5 4 KH domain KH_3 PF13014.1 EAK88458.1 - 7.8e-16 57.3 15.2 8.1e-05 22.1 0.0 5.6 6 0 0 6 6 6 4 KH domain KH_2 PF07650.12 EAK88458.1 - 2e-08 33.6 1.0 0.38 10.3 0.0 4.2 3 1 1 4 4 4 3 KH domain KH_4 PF13083.1 EAK88458.1 - 3.7e-05 23.2 0.5 0.15 11.7 0.0 4.3 4 1 0 4 4 4 1 KH domain Hormone_2 PF00123.15 EAK88458.1 - 0.025 14.4 0.6 0.62 9.9 0.1 2.5 2 0 0 2 2 2 0 Peptide hormone MIP-T3 PF10243.4 EAK88459.1 - 0.0097 14.4 25.8 0.011 14.1 17.9 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF2413 PF10310.4 EAK88459.1 - 0.025 13.4 18.6 0.036 12.8 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SprA-related PF12118.3 EAK88459.1 - 0.31 10.3 17.4 0.47 9.7 12.1 1.2 1 0 0 1 1 1 0 SprA-related family LMBR1 PF04791.11 EAK88459.1 - 0.77 8.2 7.1 0.88 8.0 4.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein BSMAP PF12280.3 EAK88459.1 - 2 8.2 11.9 1.8 8.4 7.2 1.7 1 1 0 1 1 1 0 Brain specific membrane anchored protein CDC45 PF02724.9 EAK88459.1 - 3.1 5.7 22.2 4.2 5.2 15.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 EAK88459.1 - 3.9 7.3 11.2 6.9 6.4 7.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.17 EAK88459.1 - 7.5 5.4 7.4 10 5.0 5.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter BAF PF02961.9 EAK88461.1 - 0.02 15.1 0.0 0.075 13.3 0.0 2.0 1 0 0 1 1 1 0 Barrier to autointegration factor CRAL_TRIO PF00650.15 EAK88462.1 - 9.9e-32 109.6 0.0 1.6e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EAK88462.1 - 2.7e-06 27.3 0.1 1.4e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain DUF3195 PF11424.3 EAK88462.1 - 0.1 12.7 0.1 0.34 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3195) RNase_H2-Ydr279 PF09468.5 EAK88463.1 - 8.6e-12 44.8 2.1 1.1e-11 44.5 1.5 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) SF-assemblin PF06705.6 EAK88464.1 - 1e-08 34.6 18.2 7.4e-07 28.5 12.6 2.9 1 1 0 1 1 1 1 SF-assemblin/beta giardin GSIII_N PF12437.3 EAK88464.1 - 0.0074 15.6 0.7 0.016 14.6 0.1 1.8 2 0 0 2 2 2 1 Glutamine synthetase type III N terminal Ribosomal_L35Ae PF01247.13 EAK88464.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L35Ae DUF2383 PF09537.5 EAK88464.1 - 0.13 12.5 5.2 0.073 13.3 0.6 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF2383) GAS PF13851.1 EAK88464.1 - 0.14 11.3 16.1 0.35 10.0 8.7 2.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EAK88464.1 - 0.2 11.4 13.6 2.7 7.7 0.4 3.7 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) DUF4561 PF15120.1 EAK88464.1 - 0.29 10.5 6.7 0.74 9.2 0.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4561) PRANC PF09372.5 EAK88464.1 - 0.53 10.2 13.6 0.28 11.1 0.8 3.3 1 1 1 3 3 3 0 PRANC domain DASH_Dam1 PF08653.5 EAK88464.1 - 1.4 8.7 9.1 2.8 7.7 0.5 3.9 4 1 0 4 4 4 0 DASH complex subunit Dam1 Nup54 PF13874.1 EAK88464.1 - 2.3 7.8 12.2 0.26 10.9 2.7 2.8 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 DUF16 PF01519.11 EAK88464.1 - 3.1 8.0 13.9 0.33 11.1 2.4 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 Nop25 PF09805.4 EAK88464.1 - 3.1 7.8 5.8 30 4.6 0.0 2.7 2 1 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF2400 PF09674.5 EAK88464.1 - 9.1 5.9 12.0 3 7.4 2.9 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2400) Peptidase_C6 PF00851.13 EAK88464.1 - 9.1 4.7 15.5 3.8 6.0 8.6 1.7 1 1 1 2 2 2 0 Helper component proteinase Pkinase PF00069.20 EAK88466.1 - 1.9e-54 184.5 0.5 9.8e-54 182.2 0.4 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK88466.1 - 1.6e-21 76.5 0.3 2e-15 56.5 0.3 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAK88466.1 - 0.0016 17.4 0.0 0.0045 15.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EAK88466.1 - 0.0024 17.6 1.2 0.0078 15.9 0.5 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family SNF2_N PF00176.18 EAK88469.1 - 8.2e-60 202.1 0.0 1.1e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAK88469.1 - 1.4e-11 44.0 0.0 3.2e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAK88469.1 - 1.9e-08 34.3 0.0 4.3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EAK88469.1 - 3.3e-07 29.9 0.0 7.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EAK88469.1 - 0.012 14.5 0.0 0.024 13.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Hanta_nucleocap PF00846.13 EAK88469.1 - 0.099 11.3 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein DUF4389 PF14333.1 EAK88470.1 - 0.085 12.5 0.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) PSS PF03034.10 EAK88472.1 - 1.2e-102 343.1 12.3 1.2e-102 343.1 8.5 1.6 2 0 0 2 2 2 1 Phosphatidyl serine synthase Peptidase_S15 PF02129.13 EAK88473.1 - 4.7e-77 259.0 0.2 8.5e-77 258.2 0.0 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EAK88473.1 - 1.2e-13 51.4 0.0 4.1e-13 49.7 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EAK88473.1 - 1.7e-06 28.0 0.0 2.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAK88473.1 - 0.00043 20.0 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAK88473.1 - 0.0059 16.4 0.2 0.25 11.2 0.0 2.4 2 0 0 2 2 2 1 Putative lysophospholipase TB2_DP1_HVA22 PF03134.14 EAK88475.1 - 1.9e-20 72.3 7.3 2.5e-20 72.0 5.1 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2207 PF09972.4 EAK88475.1 - 0.12 10.9 1.9 0.14 10.7 1.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SdpI PF13630.1 EAK88475.1 - 4.4 7.0 8.4 8.8 6.1 5.8 1.5 1 0 0 1 1 1 0 SdpI/YhfL protein family DinI PF06183.8 EAK88477.1 - 0.026 14.5 0.4 0.37 10.8 0.1 2.8 2 0 0 2 2 2 0 DinI-like family VP4_2 PF08935.5 EAK88478.1 - 0.097 13.2 1.3 0.32 11.6 0.0 2.3 2 0 0 2 2 2 0 Viral protein VP4 subunit Mod_r PF07200.8 EAK88480.1 - 0.00066 19.6 6.6 0.00066 19.6 4.6 2.4 2 1 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Bap31 PF05529.7 EAK88480.1 - 0.015 14.7 2.5 0.015 14.7 1.8 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like TBPIP PF07106.8 EAK88480.1 - 0.18 11.3 21.9 0.11 12.0 3.8 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Acetyltransf_11 PF13720.1 EAK88480.1 - 0.21 11.8 3.7 0.34 11.1 0.2 2.5 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 IncA PF04156.9 EAK88480.1 - 0.48 9.9 22.0 0.16 11.5 3.6 2.3 2 0 0 2 2 2 0 IncA protein MitMem_reg PF13012.1 EAK88480.1 - 0.83 9.7 8.7 0.11 12.5 0.7 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Uds1 PF15456.1 EAK88480.1 - 2.2 8.2 12.2 0.087 12.8 1.4 2.5 2 1 0 2 2 2 0 Up-regulated During Septation DUF3373 PF11853.3 EAK88480.1 - 3.8 5.9 7.2 0.35 9.3 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) Prefoldin PF02996.12 EAK88480.1 - 5.7 6.6 15.2 19 4.8 1.1 3.5 2 1 0 3 3 3 0 Prefoldin subunit Ank_2 PF12796.2 EAK88481.1 - 0.0079 16.5 0.2 0.045 14.0 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAK88481.1 - 0.034 14.6 0.1 5 7.7 0.0 2.8 2 1 1 3 3 3 0 Ankyrin repeats (many copies) PNTB PF02233.11 EAK88482.1 - 1.7e-161 538.1 18.2 1.7e-161 538.1 12.6 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EAK88482.1 - 9e-34 116.4 1.5 7.5e-33 113.4 0.2 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DUF3814 PF12769.2 EAK88482.1 - 4.7e-30 103.5 5.1 4.7e-30 103.5 3.5 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3814) AlaDh_PNT_N PF05222.10 EAK88482.1 - 1.1e-18 67.6 0.0 2.2e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.14 EAK88482.1 - 6.6e-08 31.9 0.5 0.00011 21.3 0.1 3.6 1 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EAK88482.1 - 0.0012 18.9 3.6 0.03 14.4 0.1 3.9 3 2 1 4 4 4 1 Shikimate / quinate 5-dehydrogenase TPP_enzyme_M PF00205.17 EAK88482.1 - 0.0034 17.1 0.1 0.055 13.2 0.0 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.9 EAK88482.1 - 0.0037 17.1 0.1 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 EAK88482.1 - 0.012 15.6 0.0 0.047 13.8 0.0 2.0 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain ADH_zinc_N PF00107.21 EAK88482.1 - 0.013 15.0 0.0 0.048 13.1 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase FAD_binding_2 PF00890.19 EAK88482.1 - 0.046 12.5 0.1 0.077 11.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 EAK88482.1 - 0.055 13.7 0.6 0.42 10.9 0.1 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EAK88482.1 - 0.067 13.6 0.2 0.6 10.5 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 EAK88482.1 - 0.14 12.1 0.4 10 6.0 0.0 2.7 3 0 0 3 3 3 0 NADH(P)-binding zf-MIZ PF02891.15 EAK88483.1 - 0.19 11.2 11.2 0.45 10.0 7.7 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_2 PF13639.1 EAK88483.1 - 0.61 9.9 12.7 2.1 8.2 8.8 2.0 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 EAK88483.1 - 0.62 10.1 12.8 2.4 8.2 8.9 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK88483.1 - 6.9 6.4 22.1 0.079 12.6 8.8 2.7 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_5 PF14634.1 EAK88484.1 - 0.86 9.3 15.5 0.21 11.3 7.4 2.4 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAK88484.1 - 4.7 7.3 14.9 60 3.7 9.1 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LRR_4 PF12799.2 EAK88486.1 - 2.7e-11 42.8 25.8 1.1e-06 28.0 1.5 3.7 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EAK88486.1 - 4.8e-11 42.5 1.9 1.3e-10 41.1 1.3 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 EAK88486.1 - 6e-08 32.3 11.1 0.00026 20.7 3.2 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 EAK88486.1 - 0.2 11.9 6.3 41 5.0 0.1 5.2 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 EAK88486.1 - 3.7 7.9 9.9 11 6.5 0.2 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat Pro_isomerase PF00160.16 EAK88488.1 - 1.7e-37 129.0 0.4 2e-37 128.7 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Herpes_UL25 PF01499.11 EAK88488.1 - 0.015 13.6 0.0 0.021 13.1 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family AAA_11 PF13086.1 EAK88489.1 - 6.7e-74 248.4 0.1 5.8e-73 245.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EAK88489.1 - 1.2e-63 214.1 0.2 4e-63 212.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAK88489.1 - 1.7e-10 40.5 0.0 7.3e-09 35.2 0.0 2.9 2 1 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EAK88489.1 - 4.8e-08 32.8 0.0 0.00048 19.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EAK88489.1 - 1.3e-06 28.1 0.0 0.033 13.7 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 EAK88489.1 - 0.0035 17.7 1.5 0.0035 17.7 1.0 3.9 3 1 1 4 4 4 1 AAA domain AAA PF00004.24 EAK88489.1 - 0.0047 17.1 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 EAK88489.1 - 0.0079 16.3 0.0 0.026 14.6 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 EAK88489.1 - 0.012 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EAK88489.1 - 0.015 14.2 0.1 0.15 11.0 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EAK88489.1 - 0.027 14.3 0.1 0.3 10.9 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SE PF00437.15 EAK88489.1 - 0.034 13.0 0.0 0.077 11.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 EAK88489.1 - 0.059 13.5 0.1 0.61 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EAK88489.1 - 0.075 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EAK88489.1 - 0.11 12.0 0.2 0.29 10.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-DHHC PF01529.15 EAK88490.1 - 4.4e-30 104.3 9.8 4.4e-30 104.3 6.8 2.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.2 EAK88490.1 - 1.5e-20 73.2 0.0 2.4e-10 40.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAK88490.1 - 1.2e-17 63.9 2.8 4e-08 33.5 0.1 4.5 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EAK88490.1 - 3.1e-14 51.9 0.3 1.1e-06 28.1 0.0 5.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 EAK88490.1 - 4.4e-14 51.1 2.1 0.00018 21.4 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EAK88490.1 - 9.6e-11 41.5 0.0 6.3e-05 23.0 0.0 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) NIF PF03031.13 EAK88492.1 - 0.098 12.3 0.1 0.43 10.2 0.0 1.9 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Pkinase PF00069.20 EAK88493.1 - 8.7e-46 156.1 0.3 1.8e-45 155.1 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK88493.1 - 4.6e-23 81.5 0.1 7.9e-23 80.8 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Thioredoxin PF00085.15 EAK88494.1 - 6.3e-40 135.0 0.0 7.3e-21 73.7 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EAK88494.1 - 6.6e-12 45.6 11.8 2.9e-07 30.4 0.6 4.2 2 2 2 4 4 4 4 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EAK88494.1 - 9.7e-09 35.4 0.7 0.0002 21.5 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EAK88494.1 - 3.2e-07 30.2 0.0 0.00012 21.9 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.1 EAK88494.1 - 4e-07 30.0 4.2 0.0024 17.9 0.0 4.8 5 1 0 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.16 EAK88494.1 - 3.5e-06 26.7 0.0 0.0042 16.7 0.0 2.8 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EAK88494.1 - 0.00011 21.8 0.0 0.062 12.8 0.0 2.6 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EAK88494.1 - 0.0036 16.8 0.3 4.5 6.8 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin DUF3439 PF11921.3 EAK88494.1 - 0.092 12.5 1.4 0.23 11.2 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glutaredoxin PF00462.19 EAK88494.1 - 0.23 11.4 2.2 5 7.1 0.4 2.8 2 1 0 2 2 2 0 Glutaredoxin SPC25 PF06703.6 EAK88496.1 - 0.00025 20.6 0.9 0.0031 17.0 0.6 2.1 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) ATG22 PF11700.3 EAK88496.1 - 0.0023 16.4 0.1 0.0023 16.4 0.0 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Glucos_trans_II PF14264.1 EAK88496.1 - 0.024 13.6 1.2 0.032 13.2 0.9 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII VIT1 PF01988.14 EAK88496.1 - 0.035 13.5 0.1 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 VIT family DUF3367 PF11847.3 EAK88496.1 - 0.17 9.7 0.0 0.23 9.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) DHC_N1 PF08385.7 EAK88498.1 - 3e-147 491.4 12.9 3e-147 491.4 8.9 4.2 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 Dynein_heavy PF03028.10 EAK88498.1 - 1e-104 351.0 0.1 1.5e-97 327.4 0.2 3.3 2 1 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 EAK88498.1 - 1.6e-94 316.7 21.6 6.7e-83 278.4 6.8 7.1 7 1 0 7 7 6 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EAK88498.1 - 1.1e-82 276.9 0.0 9.4e-82 273.9 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EAK88498.1 - 1e-33 116.1 0.0 3.1e-33 114.5 0.0 1.8 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 EAK88498.1 - 2e-33 115.0 0.0 7.8e-12 45.1 0.0 6.6 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) MT PF12777.2 EAK88498.1 - 7.7e-33 113.6 8.1 1.6e-32 112.5 5.6 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 EAK88498.1 - 4.1e-26 91.5 0.0 1.1e-25 90.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA PF00004.24 EAK88498.1 - 9.7e-22 77.5 0.8 2.2e-05 24.6 0.0 7.0 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.2 EAK88498.1 - 4.2e-20 71.9 0.0 7e-19 67.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EAK88498.1 - 1.2e-14 54.5 0.0 0.037 14.1 0.0 6.5 5 0 0 5 5 5 4 AAA domain AAA_16 PF13191.1 EAK88498.1 - 3e-10 40.3 0.5 0.071 13.0 0.0 5.6 5 0 0 5 5 4 2 AAA ATPase domain AAA_17 PF13207.1 EAK88498.1 - 4.8e-09 37.0 0.0 1.5 9.6 0.0 5.8 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 EAK88498.1 - 8.8e-09 35.0 1.1 0.53 10.0 0.0 4.5 4 0 0 4 4 4 2 Part of AAA domain AAA_33 PF13671.1 EAK88498.1 - 4.9e-08 32.9 1.0 1.5 8.6 0.0 5.3 5 0 0 5 5 4 2 AAA domain Zeta_toxin PF06414.7 EAK88498.1 - 8.3e-08 31.5 0.0 0.03 13.4 0.0 4.4 4 0 0 4 4 4 2 Zeta toxin Mg_chelatase PF01078.16 EAK88498.1 - 1.6e-07 30.6 0.1 0.081 12.0 0.0 4.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EAK88498.1 - 3.3e-07 30.6 1.5 0.28 11.4 0.1 6.0 5 0 0 5 5 4 1 AAA domain T2SE PF00437.15 EAK88498.1 - 4.6e-07 29.0 1.0 0.027 13.3 0.1 3.9 4 0 0 4 4 4 2 Type II/IV secretion system protein RNA_helicase PF00910.17 EAK88498.1 - 5.8e-05 23.2 0.5 18 5.5 0.0 5.5 5 0 0 5 5 5 0 RNA helicase RuvB_N PF05496.7 EAK88498.1 - 0.00029 19.9 0.2 0.094 11.7 0.0 3.5 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus FtsK_SpoIIIE PF01580.13 EAK88498.1 - 0.00042 19.8 0.2 0.74 9.2 0.0 3.6 4 0 0 4 4 4 1 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EAK88498.1 - 0.00046 19.6 2.5 4.4 6.6 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.1 EAK88498.1 - 0.00073 18.9 0.1 1.8 7.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 EAK88498.1 - 0.0026 17.3 0.4 16 5.0 0.0 3.9 4 0 0 4 4 4 0 AAA domain PduV-EutP PF10662.4 EAK88498.1 - 0.0044 16.4 1.8 0.16 11.4 0.2 3.6 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 EAK88498.1 - 0.0071 15.9 2.8 1 8.9 0.1 4.2 4 0 0 4 4 4 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EAK88498.1 - 0.026 14.4 4.9 21 5.0 0.0 4.9 5 0 0 5 5 4 0 AAA domain MobB PF03205.9 EAK88498.1 - 0.07 12.8 3.3 6.6 6.4 0.3 4.4 5 0 0 5 5 4 0 Molybdopterin guanine dinucleotide synthesis protein B Glu_cyclase_2 PF05096.7 EAK88499.1 - 2.5e-35 121.7 0.0 3.6e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine cyclotransferase FYDLN_acid PF09538.5 EAK88503.1 - 2.1 8.9 10.5 0.092 13.3 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF501 PF04417.7 EAK88504.1 - 0.16 11.7 0.3 0.53 10.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF501) GET2 PF08690.5 EAK88505.1 - 2.6 7.1 15.3 0.77 8.9 6.2 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 Sec66 PF09802.4 EAK88506.1 - 0.0022 17.4 6.9 0.003 16.9 4.8 1.2 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4271 PF14093.1 EAK88506.1 - 0.1 12.2 1.0 0.15 11.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Cep57_CLD_2 PF14197.1 EAK88508.1 - 0.0082 16.0 3.0 0.0082 16.0 2.1 4.7 3 1 1 4 4 4 2 Centrosome localisation domain of PPC89 Synaptobrevin PF00957.16 EAK88509.1 - 0.045 13.3 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Synaptobrevin PXA PF02194.10 EAK88509.1 - 7.5 6.0 6.9 0.87 9.1 1.6 1.7 2 0 0 2 2 2 0 PXA domain ATP-synt_C PF00137.16 EAK88511.1 - 4.2e-27 93.8 37.2 2.6e-15 56.0 10.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PT-VENN PF04829.8 EAK88511.1 - 0.065 12.7 7.7 0.061 12.8 3.8 2.0 1 1 1 2 2 2 0 Pre-toxin domain with VENN motif DUF1662 PF07878.6 EAK88514.1 - 0.044 13.5 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1662) Maelstrom PF13017.1 EAK88514.1 - 0.063 12.7 0.1 1.3 8.4 0.0 2.0 2 0 0 2 2 2 0 piRNA pathway germ-plasm component Pox_RNA_Pol_22 PF05273.8 EAK88515.1 - 0.0069 16.0 1.6 0.011 15.3 0.2 1.9 1 1 0 1 1 1 1 Poxvirus RNA polymerase 22 kDa subunit Pkinase PF00069.20 EAK88517.1 - 2.3e-26 92.5 0.4 9.9e-26 90.4 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK88517.1 - 0.00017 20.7 0.1 0.0083 15.2 0.0 2.9 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 EAK88517.1 - 0.00085 18.3 0.0 0.027 13.4 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Josephin PF02099.12 EAK88518.1 - 6.7e-59 198.0 0.0 1.4e-58 197.0 0.0 1.5 1 0 0 1 1 1 1 Josephin UBX PF00789.15 EAK88518.1 - 1.3e-06 28.3 0.2 5.3e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 UBX domain DUF4591 PF15261.1 EAK88518.1 - 0.0068 16.6 0.2 0.015 15.5 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4591) G10 PF01125.12 EAK88518.1 - 0.05 13.1 0.1 0.19 11.2 0.1 1.9 2 0 0 2 2 2 0 G10 protein Tna_leader PF08053.6 EAK88518.1 - 0.12 11.8 0.1 0.25 10.7 0.1 1.5 1 0 0 1 1 1 0 Tryptophanese operon leader peptide RRM_6 PF14259.1 EAK88519.1 - 7.9e-16 57.8 0.0 5e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAK88519.1 - 0.0008 18.9 0.0 0.59 9.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M14 PF00246.19 EAK88520.1 - 2.8e-44 151.8 0.0 4.7e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Noc2 PF03715.8 EAK88521.1 - 3e-29 101.8 15.4 3e-29 101.8 10.7 1.9 2 0 0 2 2 2 1 Noc2p family Sec23_helical PF04815.10 EAK88521.1 - 0.011 15.1 2.5 0.053 12.9 0.4 2.8 2 0 0 2 2 2 0 Sec23/Sec24 helical domain adh_short PF00106.20 EAK88523.1 - 1.9e-21 76.6 0.0 2.6e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAK88523.1 - 9e-07 28.7 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAK88523.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EAK88523.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TB2_DP1_HVA22 PF03134.14 EAK88526.1 - 4e-06 26.4 8.7 5.5e-06 26.0 6.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Peptidase_C13 PF01650.13 EAK88527.1 - 2.7e-38 131.7 0.9 4.4e-38 131.0 0.6 1.4 1 0 0 1 1 1 1 Peptidase C13 family Fe_hyd_lg_C PF02906.9 EAK88528.1 - 3e-87 292.5 0.0 4.6e-87 291.8 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF1546 PF07571.8 EAK88532.1 - 0.0052 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EAK88532.1 - 0.0052 16.6 0.1 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF4 PF05236.9 EAK88532.1 - 0.12 11.5 0.2 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF1777 PF08648.7 EAK88534.1 - 0.0053 16.5 22.4 0.0053 16.5 15.5 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1777) FtsH_ext PF06480.10 EAK88538.1 - 0.11 12.6 0.9 0.7 10.0 0.0 2.2 2 0 0 2 2 2 0 FtsH Extracellular Syntaxin-18_N PF10496.4 EAK88538.1 - 0.35 10.7 4.0 1.9 8.3 0.6 2.7 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus UAA PF08449.6 EAK88539.1 - 7.2e-71 238.5 24.0 1.2e-70 237.8 16.6 1.3 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EAK88539.1 - 4.9e-11 42.4 20.9 6.4e-10 38.8 5.2 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EAK88539.1 - 3.2e-08 33.6 25.8 4.8e-08 33.1 6.1 3.3 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EAK88539.1 - 0.1 12.7 0.2 0.1 12.7 0.2 3.3 3 1 0 3 3 3 0 Multidrug resistance efflux transporter Renin_r PF07850.9 EAK88539.1 - 1.6 9.0 4.5 45 4.4 0.0 3.6 3 1 1 4 4 4 0 Renin receptor-like protein TPR_11 PF13414.1 EAK88541.1 - 6.4e-12 44.9 0.5 1.4e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EAK88541.1 - 2e-09 36.6 0.6 2.7e-05 23.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAK88541.1 - 3.7e-08 32.6 4.2 3.4e-07 29.5 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EAK88541.1 - 1.5e-05 24.9 2.0 2.2e-05 24.4 0.1 2.3 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EAK88541.1 - 7.3e-05 22.2 0.0 0.0015 18.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAK88541.1 - 0.00023 21.0 0.0 0.008 16.1 0.0 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat Methyltransf_28 PF02636.12 EAK88541.1 - 0.00039 19.9 0.0 0.00073 19.0 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_17 PF13431.1 EAK88541.1 - 0.0016 18.4 1.2 0.24 11.7 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAK88541.1 - 0.0042 16.7 0.0 0.016 14.9 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAK88541.1 - 0.0077 16.7 0.0 0.73 10.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAK88541.1 - 0.2 12.0 0.0 0.51 10.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat PKD_channel PF08016.7 EAK88542.1 - 0.0033 15.9 49.1 0.034 12.5 17.6 3.3 2 1 0 2 2 2 2 Polycystin cation channel CFIA_Pcf11 PF11526.3 EAK88542.1 - 1.9 8.6 11.6 0.17 12.0 3.8 2.5 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 EGF PF00008.22 EAK88545.1 - 1e-12 47.7 34.3 0.00011 22.1 6.4 3.6 3 0 0 3 3 3 3 EGF-like domain EGF_2 PF07974.8 EAK88545.1 - 1.5e-08 34.6 41.6 0.0044 17.1 6.4 3.9 3 1 0 3 3 3 3 EGF-like domain hEGF PF12661.2 EAK88545.1 - 5e-08 32.5 20.6 0.021 14.8 1.3 3.8 3 0 0 3 3 3 3 Human growth factor-like EGF EGF_3 PF12947.2 EAK88545.1 - 0.00028 20.7 34.1 0.022 14.7 3.2 3.5 3 0 0 3 3 3 3 EGF domain Plasmod_Pvs28 PF06247.6 EAK88545.1 - 0.014 15.0 18.3 0.029 13.9 0.7 2.3 2 0 0 2 2 2 0 Plasmodium ookinete surface protein Pvs28 TMEMspv1-c74-12 PF11044.3 EAK88545.1 - 0.11 12.0 0.3 0.21 11.1 0.2 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein F_actin_cap_B PF01115.12 EAK88546.1 - 1e-19 70.7 15.1 3.3e-18 65.7 10.4 2.1 1 1 0 1 1 1 1 F-actin capping protein, beta subunit TMC PF07810.8 EAK88546.1 - 0.13 12.7 0.1 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 TMC domain Hydrolase_3 PF08282.7 EAK88547.1 - 7.8e-42 143.6 0.3 1e-41 143.2 0.2 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EAK88547.1 - 1.6e-15 57.1 0.3 1.2e-11 44.4 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EAK88547.1 - 2.8e-05 24.3 0.0 9.2e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAK88547.1 - 3.5e-05 24.3 0.0 0.00027 21.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAK88547.1 - 0.013 15.7 0.0 0.1 12.7 0.0 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAK88547.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Dus PF01207.12 EAK88548.1 - 1.3e-69 234.3 0.0 1.8e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EAK88548.1 - 4.7e-09 35.8 0.0 7.7e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 EAK88548.1 - 0.00054 19.1 0.0 0.00078 18.5 0.0 1.1 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EAK88548.1 - 0.0068 15.3 0.0 0.01 14.7 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EAK88548.1 - 0.15 11.1 0.0 0.43 9.6 0.0 1.7 1 1 1 2 2 2 0 Nitronate monooxygenase Sld5 PF05916.6 EAK88549.1 - 6.1e-07 29.6 0.0 6.5e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein AAA PF00004.24 EAK88550.1 - 4.3e-42 143.4 0.3 3.9e-41 140.3 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 EAK88550.1 - 8.7e-16 57.5 0.7 8.7e-16 57.5 0.5 1.8 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.5 EAK88550.1 - 8.1e-13 48.0 0.3 3.2e-12 46.1 0.2 2.1 1 1 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 EAK88550.1 - 5.8e-10 38.6 0.0 1.1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EAK88550.1 - 3.3e-07 30.3 0.0 7.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EAK88550.1 - 2.4e-06 27.7 0.8 0.0024 18.0 0.6 2.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EAK88550.1 - 2.5e-05 23.7 0.9 0.023 14.0 0.2 2.5 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 EAK88550.1 - 0.00011 21.9 0.1 0.00043 20.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EAK88550.1 - 0.00012 21.9 0.0 0.00046 20.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EAK88550.1 - 0.00014 22.6 0.0 0.0005 20.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAK88550.1 - 0.00024 21.1 0.1 0.0016 18.4 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EAK88550.1 - 0.00027 20.4 0.0 0.0006 19.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.8 EAK88550.1 - 0.00038 19.4 0.1 0.0029 16.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EAK88550.1 - 0.00098 19.2 2.5 0.0022 18.1 0.1 2.8 3 1 0 3 3 2 1 RNA helicase KaiC PF06745.8 EAK88550.1 - 0.0011 18.0 3.6 0.15 11.1 0.0 2.9 3 1 1 4 4 4 2 KaiC AAA_33 PF13671.1 EAK88550.1 - 0.0017 18.2 0.1 0.005 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EAK88550.1 - 0.0022 16.7 0.0 0.0047 15.7 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 EAK88550.1 - 0.0055 15.8 0.0 0.015 14.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin PhoH PF02562.11 EAK88550.1 - 0.0084 15.3 0.7 0.034 13.3 0.1 2.2 2 1 1 3 3 3 1 PhoH-like protein AAA_19 PF13245.1 EAK88550.1 - 0.0085 15.8 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 EAK88550.1 - 0.011 15.2 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EAK88550.1 - 0.02 14.0 0.1 0.049 12.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EAK88550.1 - 0.022 15.0 1.7 0.057 13.7 0.0 2.5 3 1 0 3 3 2 0 AAA domain ResIII PF04851.10 EAK88550.1 - 0.025 14.3 0.8 0.21 11.3 0.0 2.6 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit Bac_DnaA PF00308.13 EAK88550.1 - 0.027 14.1 0.1 1.1 8.8 0.1 2.5 1 1 0 1 1 1 0 Bacterial dnaA protein NACHT PF05729.7 EAK88550.1 - 0.04 13.5 0.1 1.1 8.8 0.0 2.4 1 1 1 2 2 2 0 NACHT domain Mad3_BUB1_I PF08311.7 EAK88550.1 - 0.078 12.7 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 UPF0079 PF02367.12 EAK88550.1 - 0.096 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EAK88550.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 EAK88551.1 - 9.9e-30 103.5 0.0 4.3e-29 101.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK88551.1 - 4.2e-08 32.5 0.0 4.1e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase SMN PF06003.7 EAK88551.1 - 0.38 9.7 0.0 0.38 9.7 0.0 3.3 3 0 0 3 3 3 0 Survival motor neuron protein (SMN) ADK PF00406.17 EAK88552.1 - 2.4e-43 147.6 0.0 2.8e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EAK88552.1 - 1.2e-08 35.3 0.0 2.4e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAK88552.1 - 2.1e-08 34.1 0.0 3.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAK88552.1 - 1.5e-05 25.8 0.1 4.1e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EAK88552.1 - 0.001 18.4 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA PF00004.24 EAK88552.1 - 0.026 14.7 0.0 0.073 13.2 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EAK88552.1 - 0.034 13.2 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin 14-3-3 PF00244.15 EAK88553.1 - 1.8e-34 118.8 5.1 2.3e-34 118.5 3.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EAK88553.1 - 0.0018 18.1 0.4 0.0067 16.3 0.3 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat DUF2225 PF09986.4 EAK88553.1 - 0.0085 15.5 3.4 0.019 14.4 0.4 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_14 PF13428.1 EAK88553.1 - 0.011 16.3 0.4 3.3 8.6 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAK88553.1 - 0.015 14.8 2.5 3.1 7.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EAK88553.1 - 0.043 13.4 0.8 0.27 10.9 0.4 2.4 2 1 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 EAK88553.1 - 0.059 13.3 2.9 4.3 7.4 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat EST1 PF10374.4 EAK88553.1 - 0.29 11.1 3.1 15 5.5 0.3 3.4 1 1 1 2 2 2 0 Telomerase activating protein Est1 RRM_5 PF13893.1 EAK88554.1 - 4.7e-05 23.1 0.0 0.00016 21.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAK88554.1 - 0.0001 21.8 0.0 0.00024 20.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK88554.1 - 0.0093 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Glycolytic PF00274.14 EAK88555.1 - 6.6e-164 544.3 0.0 7.5e-164 544.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Ribosomal_L27e PF01777.13 EAK88556.1 - 2.7e-24 85.1 1.4 4e-24 84.5 0.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EAK88556.1 - 0.00043 19.9 0.1 0.00076 19.1 0.1 1.4 1 0 0 1 1 1 1 KOW motif ATHILA PF03078.10 EAK88556.1 - 0.033 12.7 0.0 0.043 12.4 0.0 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family Pkinase PF00069.20 EAK88557.1 - 1.2e-33 116.3 0.0 4.8e-16 58.7 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAK88557.1 - 1.1e-07 31.1 0.0 0.029 13.4 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase DUF4524 PF15025.1 EAK88558.1 - 0.088 12.2 0.1 0.13 11.7 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4524) CPSF_A PF03178.10 EAK88559.1 - 2.9e-30 105.4 3.7 6.2e-29 101.1 1.3 3.2 2 1 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EAK88559.1 - 7.5e-14 50.7 0.7 2.2e-12 45.8 1.2 2.7 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term SNARE PF05739.14 EAK88560.1 - 1.6e-15 56.5 1.3 1.6e-15 56.5 0.9 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EAK88560.1 - 2.3e-14 53.4 2.9 2.3e-14 53.4 2.0 2.6 2 1 0 2 2 2 1 Syntaxin Corona_S2 PF01601.11 EAK88560.1 - 0.00078 17.6 6.5 0.08 11.0 0.5 2.3 2 0 0 2 2 2 2 Coronavirus S2 glycoprotein C9orf72-like PF15019.1 EAK88560.1 - 0.002 17.4 1.6 0.46 9.6 0.0 3.0 3 0 0 3 3 3 1 C9orf72-like protein family Syntaxin_2 PF14523.1 EAK88560.1 - 0.0025 17.8 9.6 0.55 10.2 0.5 3.5 2 1 1 3 3 3 2 Syntaxin-like protein Tup_N PF08581.5 EAK88560.1 - 0.0075 16.4 1.7 0.0075 16.4 1.2 2.7 2 0 0 2 2 2 1 Tup N-terminal MCPsignal PF00015.16 EAK88560.1 - 0.012 15.1 5.7 0.65 9.5 0.3 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Prominin PF05478.6 EAK88560.1 - 0.012 13.1 0.3 0.012 13.1 0.2 2.3 2 1 0 2 2 2 0 Prominin UPF0118 PF01594.11 EAK88560.1 - 0.034 13.1 0.4 0.034 13.1 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function DUF20 CcdA PF07362.7 EAK88560.1 - 0.04 13.7 0.2 0.92 9.4 0.0 2.6 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Lipoprotein_7 PF01540.11 EAK88560.1 - 0.044 12.8 1.5 0.25 10.3 0.1 2.3 3 0 0 3 3 3 0 Adhesin lipoprotein Syntaxin-6_N PF09177.6 EAK88560.1 - 0.045 14.1 7.9 2.4 8.6 1.3 3.0 2 1 2 4 4 4 0 Syntaxin 6, N-terminal DUF4208 PF13907.1 EAK88560.1 - 0.093 12.9 2.1 0.31 11.2 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4208) IFT57 PF10498.4 EAK88560.1 - 0.22 10.2 10.0 0.35 9.5 0.2 2.8 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 Vac_Fusion PF02346.11 EAK88560.1 - 0.25 10.7 3.3 2.5 7.5 0.0 3.3 3 0 0 3 3 3 0 Chordopoxvirus fusion protein TF_AP-2 PF03299.9 EAK88560.1 - 0.26 10.7 2.9 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Transcription factor AP-2 Tweety PF04906.8 EAK88560.1 - 0.44 8.9 4.1 4.8 5.5 0.5 2.4 2 1 0 2 2 2 0 Tweety DUF1664 PF07889.7 EAK88560.1 - 0.45 10.3 9.4 1 9.1 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF3540 PF12059.3 EAK88560.1 - 0.62 9.6 4.1 1.2 8.7 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3540) DUF2397 PF09660.5 EAK88560.1 - 0.65 8.5 5.8 0.94 7.9 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) Laminin_II PF06009.7 EAK88560.1 - 0.96 9.1 5.7 2.5 7.8 1.0 2.4 2 0 0 2 2 2 0 Laminin Domain II COG2 PF06148.6 EAK88560.1 - 1.5 8.6 6.0 9.2 6.1 0.4 2.7 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0449 PF15136.1 EAK88560.1 - 1.6 9.0 10.9 36 4.6 3.6 3.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 ATG16 PF08614.6 EAK88560.1 - 3.1 7.5 11.2 2.1 8.1 1.4 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.4 EAK88560.1 - 3.6 7.7 8.4 15 5.7 1.5 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Use1 PF09753.4 EAK88560.1 - 9.4 5.5 10.2 0.34 10.3 0.4 2.8 2 1 0 3 3 3 0 Membrane fusion protein Use1 YchF-GTPase_C PF06071.8 EAK88561.1 - 3.4e-39 132.4 0.3 9.6e-39 131.0 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EAK88561.1 - 7.1e-17 61.4 0.0 2.5e-16 59.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAK88561.1 - 1.1e-06 28.0 0.0 3.6e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B HAUS-augmin3 PF14932.1 EAK88561.1 - 0.014 14.5 0.3 0.022 13.9 0.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 AAA_10 PF12846.2 EAK88561.1 - 0.016 14.6 0.0 0.058 12.8 0.0 2.1 1 1 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 EAK88561.1 - 0.016 15.9 0.0 0.15 12.8 0.0 2.7 1 1 0 1 1 1 0 AAA domain TGS PF02824.16 EAK88561.1 - 0.034 13.9 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 TGS domain AAA PF00004.24 EAK88561.1 - 0.043 14.0 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EAK88561.1 - 0.058 13.2 0.0 0.47 10.3 0.0 2.4 2 2 0 2 2 2 0 AAA domain zf-Apc11 PF12861.2 EAK88562.1 - 4.5e-27 93.7 7.2 6e-27 93.3 5.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EAK88562.1 - 6.3e-25 87.0 8.6 8.3e-25 86.7 5.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EAK88562.1 - 3e-07 30.1 17.3 3.5e-06 26.7 12.0 2.3 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EAK88562.1 - 2.8e-06 26.9 6.9 2.8e-06 26.9 4.8 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAK88562.1 - 0.00014 21.7 15.1 0.00038 20.4 7.2 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAK88562.1 - 0.00015 21.3 15.0 0.0012 18.4 10.3 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAK88562.1 - 0.0006 19.4 14.1 0.014 15.0 8.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAK88562.1 - 0.00073 19.3 3.4 0.00073 19.3 2.3 2.7 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EAK88562.1 - 0.0017 17.9 12.1 0.019 14.5 6.2 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-HIT PF04438.11 EAK88562.1 - 0.03 13.9 1.9 0.03 13.9 1.3 2.5 3 0 0 3 3 2 0 HIT zinc finger zf-Nse PF11789.3 EAK88562.1 - 0.13 11.8 5.2 0.26 10.8 3.6 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EAK88562.1 - 0.47 10.2 8.8 3 7.6 6.0 2.4 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 EAK88562.1 - 0.56 10.3 8.0 1.3 9.2 5.5 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.3 EAK88562.1 - 0.6 10.1 14.4 6 6.9 9.9 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain RecR PF02132.10 EAK88562.1 - 1.5 8.2 7.7 3.5 7.1 0.9 3.2 3 0 0 3 3 3 0 RecR protein zf-HC5HC2H_2 PF13832.1 EAK88562.1 - 2.7 8.0 8.7 0.72 9.8 3.6 1.9 1 1 1 2 2 2 0 PHD-zinc-finger like domain RINGv PF12906.2 EAK88562.1 - 7.4 6.6 12.4 27 4.8 8.0 2.3 1 1 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 EAK88562.1 - 8.4 6.2 13.0 6.2 6.6 0.1 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_5 PF13719.1 EAK88562.1 - 9.1 5.9 11.2 45 3.7 0.0 4.3 3 1 1 4 4 4 0 zinc-ribbon domain DZR PF12773.2 EAK88562.1 - 9.2 6.1 11.4 1.4e+02 2.3 7.9 2.3 1 1 0 1 1 1 0 Double zinc ribbon Acetyltransf_1 PF00583.19 EAK88563.1 - 1.3e-16 60.3 0.0 1.9e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAK88563.1 - 3.1e-08 33.6 0.0 4.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAK88563.1 - 1.7e-07 31.2 0.1 2.1e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAK88563.1 - 3.5e-06 27.1 0.0 4.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAK88563.1 - 8.8e-05 22.1 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EAK88563.1 - 0.00028 20.7 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAK88563.1 - 0.0024 17.7 0.0 0.0043 16.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EAK88563.1 - 0.093 12.8 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Sua5_yciO_yrdC PF01300.13 EAK88564.1 - 5.5e-47 159.3 0.0 7.3e-47 158.9 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EAK88564.1 - 5.2e-10 39.4 0.0 1.3e-09 38.1 0.0 1.6 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding LSM PF01423.17 EAK88565.1 - 1.7e-14 53.0 0.0 2.5e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAK88565.1 - 0.0097 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Mito_carr PF00153.22 EAK88566.1 - 3.3e-42 142.0 1.2 1.3e-15 56.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein LPAM_1 PF08139.7 EAK88566.1 - 0.17 12.1 0.6 0.6 10.4 0.4 2.0 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Reo_sigmaC PF04582.7 EAK88567.1 - 0.0037 16.4 6.0 0.0037 16.4 4.1 2.9 2 1 0 2 2 2 1 Reovirus sigma C capsid protein DUF4200 PF13863.1 EAK88567.1 - 0.012 15.5 14.6 0.06 13.2 10.1 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF724 PF05266.9 EAK88567.1 - 1.5 8.4 15.7 0.066 12.8 5.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.7 EAK88567.1 - 2 8.2 7.1 4.7 7.0 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) WD40 PF00400.27 EAK88568.1 - 1.4e-06 27.9 6.4 0.00016 21.3 0.2 3.0 3 1 0 3 3 3 2 WD domain, G-beta repeat PK PF00224.16 EAK88569.1 - 3.4e-136 453.4 1.8 1.4e-134 448.1 0.4 2.0 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.11 EAK88569.1 - 3.6e-30 103.9 1.4 1e-29 102.4 1.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EAK88569.1 - 0.0022 16.9 0.0 0.0061 15.4 0.0 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family RNA_pol_Rbc25 PF08292.7 EAK88570.1 - 5.4e-30 104.1 1.3 2.3e-29 102.0 0.9 1.9 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EAK88570.1 - 7.8e-14 51.5 0.0 1.4e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EAK88570.1 - 0.0018 18.2 0.1 0.0059 16.6 0.0 1.9 2 0 0 2 2 2 1 S1 RNA binding domain Rab5ip PF07019.7 EAK88571.1 - 1.9e-14 53.5 5.1 2.3e-14 53.3 3.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) PgpA PF04608.8 EAK88571.1 - 0.092 12.5 1.1 0.12 12.2 0.8 1.2 1 0 0 1 1 1 0 Phosphatidylglycerophosphatase A Peptidase_M16 PF00675.15 EAK88572.1 - 7e-29 100.5 0.4 1.9e-28 99.0 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAK88572.1 - 2.5e-15 56.6 2.1 1.1e-06 28.4 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain HIT PF01230.18 EAK88573.1 - 2.3e-25 88.9 0.0 2.8e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EAK88573.1 - 1.4e-18 67.1 0.1 1.8e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Lambda_tail_I PF06805.7 EAK88573.1 - 0.031 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I zf-CCCH PF00642.19 EAK88574.1 - 6.5e-09 35.2 2.1 1.7e-08 33.9 1.4 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 EAK88574.1 - 0.021 14.4 7.5 0.059 13.0 5.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK88574.1 - 0.68 10.0 16.0 0.034 14.1 6.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAK88574.1 - 4.1 7.1 9.6 13 5.5 6.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CSTF2_hinge PF14327.1 EAK88575.1 - 5.9e-22 77.5 1.6 5.9e-22 77.5 1.1 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EAK88575.1 - 4.6e-18 64.6 0.0 8.9e-18 63.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK88575.1 - 7.1e-13 48.3 0.0 1.6e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK88575.1 - 3.4e-05 23.6 0.0 6.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C97 PF05903.9 EAK88576.1 - 4.6e-43 146.5 0.0 7.1e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.5 EAK88576.1 - 2e-17 62.7 0.2 2e-17 62.7 0.1 2.3 2 0 0 2 2 2 1 PUB domain UBA PF00627.26 EAK88576.1 - 0.012 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain DUF4279 PF14106.1 EAK88576.1 - 0.016 15.0 0.0 0.3 10.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4279) Tox-PL-2 PF15643.1 EAK88576.1 - 0.046 13.6 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Papain fold toxin 2 HXXSHH PF07586.6 EAK88576.1 - 0.78 8.6 4.3 0.22 10.4 0.2 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1552) GP40 PF11025.3 EAK88576.1 - 6.5 6.3 9.2 3.1 7.3 2.0 2.2 2 0 0 2 2 2 0 Glycoprotein GP40 of Cryptosporidium Peptidase_C12 PF01088.16 EAK88577.1 - 1.8e-54 184.1 0.0 2.8e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Bacillus_HBL PF05791.6 EAK88577.1 - 0.002 17.5 1.3 0.0037 16.6 0.9 1.4 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) DUF953 PF06110.6 EAK88577.1 - 0.012 15.0 0.0 0.047 13.1 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Cortex-I_coil PF09304.5 EAK88577.1 - 0.21 11.6 3.7 0.42 10.6 2.5 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil ENTH PF01417.15 EAK88578.1 - 1.6e-11 44.1 3.8 9.4e-09 35.2 0.0 2.7 2 0 0 2 2 2 2 ENTH domain Colicin_Pyocin PF01320.13 EAK88578.1 - 0.1 12.4 1.4 0.68 9.8 0.0 3.1 3 0 0 3 3 3 0 Colicin immunity protein / pyocin immunity protein HEAT PF02985.17 EAK88578.1 - 0.13 12.3 0.0 7.8 6.8 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat Abhydrolase_5 PF12695.2 EAK88579.1 - 5.1e-12 45.7 0.0 7.3e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAK88579.1 - 1.9e-07 31.2 0.0 4.2e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAK88579.1 - 0.00024 20.7 0.1 0.0024 17.4 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAK88579.1 - 0.00029 20.1 0.2 0.01 15.0 0.1 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EAK88579.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 EAK88579.1 - 0.018 14.8 0.1 0.038 13.8 0.1 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF3799 PF12684.2 EAK88579.1 - 0.14 11.5 0.3 0.2 10.9 0.2 1.2 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) RRM_1 PF00076.17 EAK88580.1 - 6.7e-20 70.4 0.1 1.2e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK88580.1 - 5.7e-16 58.2 0.3 1.9e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK88580.1 - 4.4e-05 23.2 0.6 7.9e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Actin PF00022.14 EAK88581.1 - 1.5e-92 310.0 0.0 1.8e-92 309.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EAK88581.1 - 0.00045 18.9 0.0 0.0028 16.3 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein zf-A20 PF01754.11 EAK88582.1 - 4.5e-12 45.3 9.1 4.5e-12 45.3 6.3 2.7 4 0 0 4 4 4 1 A20-like zinc finger zf-AN1 PF01428.11 EAK88582.1 - 2.1e-11 43.5 11.1 2.1e-11 43.5 7.7 2.0 2 0 0 2 2 2 1 AN1-like Zinc finger zf-CSL PF05207.8 EAK88582.1 - 0.091 12.2 3.2 0.19 11.2 2.2 1.6 1 0 0 1 1 1 0 CSL zinc finger Ribosomal_S19e PF01090.14 EAK88583.1 - 4.7e-50 168.6 0.0 5.4e-50 168.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e ORC4_C PF14629.1 EAK88583.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Mnd1 PF03962.10 EAK88584.1 - 5.1e-23 81.7 0.3 5.5e-23 81.6 0.2 1.0 1 0 0 1 1 1 1 Mnd1 family TrmB PF01978.14 EAK88584.1 - 0.019 14.6 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.11 EAK88584.1 - 0.06 13.4 0.0 0.067 13.2 0.0 1.0 1 0 0 1 1 1 0 Penicillinase repressor DSPc PF00782.15 EAK88585.1 - 9.3e-29 99.6 0.1 2.9e-28 98.0 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAK88585.1 - 0.002 17.4 0.2 0.0046 16.3 0.1 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Gelsolin PF00626.17 EAK88585.1 - 0.1 12.3 1.6 1 9.0 0.0 3.4 4 0 0 4 4 4 0 Gelsolin repeat ATP-synt_C PF00137.16 EAK88586.1 - 1.2e-26 92.3 29.9 1.2e-14 53.9 7.6 2.0 2 0 0 2 2 2 2 ATP synthase subunit C DUF872 PF05915.7 EAK88586.1 - 0.021 14.6 3.7 0.7 9.7 0.2 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Glycophorin_A PF01102.13 EAK88586.1 - 8.6 6.1 9.4 0.33 10.7 1.7 1.9 2 0 0 2 2 2 0 Glycophorin A DUF2721 PF11026.3 EAK88586.1 - 10 5.8 7.3 1.5 8.4 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) EMP24_GP25L PF01105.19 EAK88587.1 - 7.2e-19 68.2 0.4 8.3e-19 68.0 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UQ_con PF00179.21 EAK88588.1 - 3.8e-44 149.5 0.0 4.3e-44 149.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAK88588.1 - 0.034 13.8 0.1 0.042 13.6 0.1 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B AdoMet_Synthase PF01941.14 EAK88588.1 - 0.058 11.8 0.0 0.07 11.6 0.0 1.0 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) DUF3584 PF12128.3 EAK88589.1 - 5e-06 24.1 15.8 5e-06 24.1 10.9 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) Phage_lysis PF03245.8 EAK88589.1 - 0.0073 16.3 2.6 0.0073 16.3 1.8 2.8 3 1 0 3 3 2 1 Bacteriophage Rz lysis protein OmpH PF03938.9 EAK88589.1 - 0.0078 16.1 9.0 0.0078 16.1 6.3 2.4 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) V-SNARE PF05008.10 EAK88589.1 - 0.022 14.9 5.4 0.022 14.9 3.7 3.7 3 2 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Cep57_MT_bd PF06657.8 EAK88589.1 - 0.039 13.8 8.6 0.48 10.3 0.5 2.8 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.7 EAK88589.1 - 0.069 12.9 13.2 0.36 10.6 3.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PBC PF03792.8 EAK88589.1 - 0.11 12.2 15.1 0.017 14.8 5.0 3.0 1 1 3 4 4 4 0 PBC domain Lectin_N PF03954.9 EAK88589.1 - 0.13 11.7 9.9 0.066 12.6 1.0 2.7 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF3086 PF11285.3 EAK88589.1 - 0.67 8.7 12.0 0.084 11.6 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Remorin_C PF03763.8 EAK88589.1 - 2.7 7.5 14.4 5 6.6 3.1 2.8 2 1 0 2 2 2 0 Remorin, C-terminal region AAA_13 PF13166.1 EAK88589.1 - 2.9 6.2 33.6 0.65 8.3 11.2 2.1 1 1 1 2 2 2 0 AAA domain Mst1_SARAH PF11629.3 EAK88589.1 - 6.3 6.6 12.9 1.1 9.1 1.2 4.0 3 1 1 4 4 4 0 C terminal SARAH domain of Mst1 SF-assemblin PF06705.6 EAK88589.1 - 6.4 5.8 29.1 1 8.4 10.6 2.6 1 1 1 2 2 2 0 SF-assemblin/beta giardin Phasin PF05597.6 EAK88589.1 - 6.9 6.4 15.2 0.16 11.7 3.0 2.8 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TMP_2 PF06791.8 EAK88589.1 - 9.1 5.8 7.5 7.2 6.1 0.3 2.8 2 1 0 2 2 2 0 Prophage tail length tape measure protein AAA PF00004.24 EAK88590.1 - 4.1e-94 311.7 0.0 8.2e-47 158.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EAK88590.1 - 4.4e-23 81.0 0.2 1.3e-22 79.5 0.1 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EAK88590.1 - 4.4e-13 48.8 0.0 9.7e-06 24.7 0.0 2.9 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EAK88590.1 - 3.9e-12 47.0 0.1 1.4e-05 25.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EAK88590.1 - 4.8e-12 46.2 1.0 0.0003 20.8 0.0 3.9 3 2 1 4 4 4 2 AAA ATPase domain AAA_2 PF07724.9 EAK88590.1 - 8.9e-12 45.2 0.0 2.9e-06 27.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EAK88590.1 - 1.6e-11 44.4 0.3 0.00048 20.2 0.0 4.3 3 2 0 3 3 2 2 AAA domain AAA_5 PF07728.9 EAK88590.1 - 5.1e-11 42.4 0.1 5.2e-06 26.2 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EAK88590.1 - 6.2e-11 42.3 0.0 2.5e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 EAK88590.1 - 4.4e-10 39.0 0.0 1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 EAK88590.1 - 2.2e-08 34.0 0.0 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EAK88590.1 - 4.1e-08 32.8 3.8 0.036 13.4 0.0 3.9 3 1 1 4 4 3 3 AAA domain TIP49 PF06068.8 EAK88590.1 - 5.6e-08 31.9 0.0 0.0012 17.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 EAK88590.1 - 2.2e-07 30.1 0.0 0.0058 15.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 EAK88590.1 - 3.6e-07 30.5 0.0 0.026 14.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EAK88590.1 - 5.9e-07 28.8 0.3 0.032 13.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EAK88590.1 - 6.8e-07 29.4 0.0 0.024 14.8 0.0 3.0 3 0 0 3 3 2 2 RNA helicase IstB_IS21 PF01695.12 EAK88590.1 - 7.9e-07 28.6 0.0 0.037 13.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EAK88590.1 - 9.5e-07 28.4 2.6 0.011 15.4 0.2 2.9 3 0 0 3 3 2 2 Part of AAA domain Arch_ATPase PF01637.13 EAK88590.1 - 2.8e-06 27.1 0.0 0.024 14.3 0.0 3.2 2 2 1 3 3 3 2 Archaeal ATPase NACHT PF05729.7 EAK88590.1 - 4.7e-06 26.3 0.0 0.41 10.2 0.0 3.9 3 1 0 4 4 4 2 NACHT domain AAA_28 PF13521.1 EAK88590.1 - 9.5e-06 25.6 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 EAK88590.1 - 1.3e-05 25.2 0.0 0.043 13.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 EAK88590.1 - 3.7e-05 23.4 0.2 0.33 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 EAK88590.1 - 5e-05 22.5 0.1 2.4 7.2 0.0 3.4 2 1 0 3 3 3 1 KaiC ResIII PF04851.10 EAK88590.1 - 9.9e-05 22.2 0.0 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EAK88590.1 - 0.00011 22.5 0.0 0.37 11.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter NB-ARC PF00931.17 EAK88590.1 - 0.00013 20.8 0.0 0.32 9.8 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.21 EAK88590.1 - 0.00016 21.1 0.0 0.23 10.9 0.0 3.1 2 2 0 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EAK88590.1 - 0.00017 20.5 0.0 0.39 9.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 EAK88590.1 - 0.00019 21.1 0.0 0.078 12.6 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein Viral_helicase1 PF01443.13 EAK88590.1 - 0.00025 20.6 0.0 0.025 14.0 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EAK88590.1 - 0.00098 18.8 0.2 1.6 8.3 0.0 3.6 3 0 0 3 3 3 1 NTPase DUF815 PF05673.8 EAK88590.1 - 0.0012 17.8 0.0 0.46 9.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 EAK88590.1 - 0.0017 17.6 0.3 1.1 8.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.6 EAK88590.1 - 0.0037 16.8 0.0 2.8 7.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EAK88590.1 - 0.0041 17.0 0.0 3.1 7.6 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase DUF2075 PF09848.4 EAK88590.1 - 0.0051 15.8 0.0 1.2 8.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EAK88590.1 - 0.012 15.2 0.0 5.2 6.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain Vps4_C PF09336.5 EAK88590.1 - 0.015 15.1 0.0 0.046 13.6 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain UPF0079 PF02367.12 EAK88590.1 - 0.022 14.3 0.1 5.7 6.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EAK88590.1 - 0.025 14.0 0.5 7 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA-like domain KAP_NTPase PF07693.9 EAK88590.1 - 0.031 13.2 0.0 2.2 7.2 0.0 3.0 2 2 1 4 4 4 0 KAP family P-loop domain Cytidylate_kin2 PF13189.1 EAK88590.1 - 0.034 14.0 0.0 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_23 PF13476.1 EAK88590.1 - 0.035 14.4 0.0 5.5 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EAK88590.1 - 0.057 12.9 0.0 4.5 6.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain KTI12 PF08433.5 EAK88590.1 - 0.07 12.3 0.1 6.7 5.8 0.0 2.7 3 0 0 3 3 3 0 Chromatin associated protein KTI12 DEAD PF00270.24 EAK88590.1 - 0.077 12.4 0.0 20 4.6 0.0 3.2 2 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_11 PF13086.1 EAK88590.1 - 0.099 12.1 0.0 13 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 EAK88590.1 - 0.13 11.6 0.2 9.2 5.6 0.1 3.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Rad17 PF03215.10 EAK88590.1 - 0.22 10.1 0.0 4.3 5.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_21 PF13304.1 EAK88590.1 - 0.25 11.2 0.2 28 4.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain DAP3 PF10236.4 EAK88590.1 - 0.35 9.7 0.0 18 4.1 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Oxysterol_BP PF01237.13 EAK88591.1 - 1.1e-116 389.2 1.0 1.8e-116 388.5 0.7 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein AP_endonuc_2 PF01261.19 EAK88592.1 - 6.7e-28 97.4 0.0 3.9e-27 94.9 0.0 1.9 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Ribosomal_S21e PF01249.13 EAK88593.1 - 6.1e-33 112.6 0.0 6.6e-33 112.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e UCH PF00443.24 EAK88594.1 - 2.5e-44 151.4 0.6 3.1e-44 151.1 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAK88594.1 - 8.5e-14 51.6 1.6 1.2e-13 51.2 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EAK88594.1 - 6.2e-07 28.7 0.0 5.7e-06 25.6 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin family RE_NgoPII PF09521.5 EAK88594.1 - 0.0025 16.6 0.1 0.0046 15.7 0.1 1.3 1 0 0 1 1 1 1 NgoPII restriction endonuclease Glycos_transf_1 PF00534.15 EAK88595.1 - 6.7e-28 97.2 0.0 1.7e-27 95.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EAK88595.1 - 1.2e-05 25.4 0.0 7.1e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EAK88595.1 - 9.6e-05 22.5 0.0 0.00024 21.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Mannosyl_trans PF05007.8 EAK88596.1 - 4.3e-54 183.8 26.4 7e-54 183.1 18.3 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) TRM13 PF05206.9 EAK88597.1 - 4.9e-23 81.7 11.1 4e-22 78.6 2.5 3.6 2 1 0 2 2 2 2 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 EAK88597.1 - 7.4e-11 41.2 2.1 7.4e-11 41.2 1.5 2.1 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein WBS_methylT PF12589.3 EAK88598.1 - 6e-21 74.7 2.3 8.9e-21 74.1 1.6 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EAK88598.1 - 1.1e-08 35.4 0.0 2.2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAK88598.1 - 0.00011 21.9 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAK88598.1 - 0.00037 20.0 0.0 0.00081 19.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAK88598.1 - 0.00042 20.7 0.0 0.00092 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAK88598.1 - 0.0023 18.4 0.0 0.0037 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAK88598.1 - 0.048 14.0 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EAK88599.1 - 6.2e-54 182.8 0.0 8.3e-54 182.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK88599.1 - 1.6e-29 102.7 0.2 1.6e-28 99.4 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAK88599.1 - 1.8e-06 27.1 0.5 2.5e-05 23.4 0.1 2.6 2 1 0 2 2 2 1 Kinase-like Baculo_LEF-2 PF03041.9 EAK88599.1 - 0.036 13.7 1.9 0.084 12.5 1.3 1.5 1 0 0 1 1 1 0 lef-2 AAA_23 PF13476.1 EAK88600.1 - 7e-21 75.4 6.9 7e-21 75.4 4.8 6.6 1 1 3 4 4 2 1 AAA domain SMC_N PF02463.14 EAK88600.1 - 6.5e-12 45.1 20.6 1e-07 31.3 0.0 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EAK88600.1 - 4.2e-07 29.8 0.0 1.3e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 EAK88600.1 - 1.8e-05 25.0 0.1 8e-05 22.9 0.0 5.2 4 1 1 5 5 3 2 ABC transporter AAA_16 PF13191.1 EAK88600.1 - 0.00012 22.1 0.3 0.00054 19.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.1 EAK88600.1 - 0.00047 18.7 0.0 0.00047 18.7 0.0 6.1 3 1 3 6 6 6 3 AAA domain AAA_29 PF13555.1 EAK88600.1 - 0.00053 19.4 0.0 0.0014 18.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EAK88600.1 - 0.00078 19.4 10.6 0.00078 19.4 7.4 5.9 1 1 1 3 3 2 1 AAA domain AAA_22 PF13401.1 EAK88600.1 - 0.0062 16.6 0.0 0.0062 16.6 0.0 3.9 3 1 1 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.13 EAK88600.1 - 0.11 11.9 0.2 0.45 9.9 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 EAK88600.1 - 0.18 11.5 0.0 0.49 10.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EAK88600.1 - 2.3 9.0 7.9 3.5 8.4 0.0 4.5 2 1 0 2 2 1 0 AAA domain WD40 PF00400.27 EAK88601.1 - 4e-29 99.4 13.4 2.3e-07 30.4 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EAK88601.1 - 1.4e-26 92.1 1.9 5.8e-25 86.9 0.5 2.7 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex EF-1_beta_acid PF10587.4 EAK88601.1 - 0.14 12.3 1.6 0.38 10.9 1.1 1.8 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region EF-hand_1 PF00036.27 EAK88602.1 - 3.3e-26 88.5 4.7 3.7e-07 28.9 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EAK88602.1 - 8.2e-26 89.9 1.8 4.7e-13 49.0 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EAK88602.1 - 3.4e-19 66.9 0.8 0.0032 17.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EAK88602.1 - 2.5e-18 64.4 1.7 0.0008 18.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EAK88602.1 - 1.9e-12 46.5 8.1 2.3e-05 23.9 0.3 4.1 3 2 2 5 5 5 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EAK88602.1 - 1.9e-11 43.9 0.1 4e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EAK88602.1 - 0.001 18.7 4.0 0.71 9.6 0.3 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EAK88602.1 - 0.0031 17.3 0.0 0.99 9.3 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.8 EAK88602.1 - 0.064 12.7 0.1 0.9 9.0 0.0 2.6 2 1 2 4 4 4 0 Caleosin related protein Utp11 PF03998.8 EAK88603.1 - 4.5e-53 180.5 20.8 5.5e-53 180.2 14.4 1.1 1 0 0 1 1 1 1 Utp11 protein DIRP PF06584.8 EAK88603.1 - 0.0058 16.4 0.4 0.015 15.1 0.3 1.7 1 0 0 1 1 1 1 DIRP BPL_N PF09825.4 EAK88603.1 - 0.016 14.0 3.7 0.018 13.8 2.6 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Bt_P21 PF05560.6 EAK88603.1 - 0.023 14.0 0.3 0.057 12.8 0.1 1.6 1 1 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein IncA PF04156.9 EAK88603.1 - 7 6.2 9.1 22 4.6 6.3 1.8 1 1 0 1 1 1 0 IncA protein Coq4 PF05019.8 EAK88604.1 - 1.8e-48 164.3 0.1 2.1e-45 154.3 0.0 2.1 2 0 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 zf-C2H2_jaz PF12171.3 EAK88605.1 - 7.9e-08 32.2 3.6 0.00012 22.1 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EAK88605.1 - 4.9e-05 23.3 5.3 0.042 14.1 0.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EAK88605.1 - 0.0001 22.3 6.7 0.072 13.4 0.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 EAK88605.1 - 0.0019 17.7 3.3 0.018 14.6 0.1 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 EAK88605.1 - 0.0023 17.9 3.4 1 9.5 0.1 2.5 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) DUF629 PF04780.7 EAK88605.1 - 0.016 13.7 0.1 0.017 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-Di19 PF05605.7 EAK88605.1 - 0.018 15.1 3.2 1.4 9.1 0.2 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.17 EAK88605.1 - 0.029 14.4 2.0 0.049 13.7 1.4 1.4 1 0 0 1 1 1 0 LIM domain Rad50_zn_hook PF04423.9 EAK88605.1 - 0.21 11.1 1.8 0.51 9.8 0.1 2.4 1 1 1 2 2 2 0 Rad50 zinc hook motif PyrI_C PF02748.10 EAK88605.1 - 0.46 9.9 4.1 2.5 7.6 0.3 2.5 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain SmpA_OmlA PF04355.8 EAK88606.1 - 0.16 11.6 0.3 0.3 10.7 0.0 1.5 1 1 1 2 2 2 0 SmpA / OmlA family Prefoldin PF02996.12 EAK88607.1 - 0.0093 15.6 2.0 0.04 13.5 0.4 2.3 2 0 0 2 2 2 1 Prefoldin subunit Exonuc_VII_L PF02601.10 EAK88607.1 - 0.028 13.6 2.0 0.032 13.4 1.0 1.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit Tho2 PF11262.3 EAK88607.1 - 0.11 11.5 3.7 0.66 8.9 2.0 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Fzo_mitofusin PF04799.8 EAK88607.1 - 0.29 10.4 2.2 0.42 9.9 1.5 1.3 1 0 0 1 1 1 0 fzo-like conserved region Cut12 PF11500.3 EAK88609.1 - 0.02 14.5 1.6 0.02 14.5 1.1 2.6 2 1 0 2 2 2 0 Spindle pole body formation-associated protein DUF2482 PF10655.4 EAK88609.1 - 0.078 13.0 0.9 2.7 8.0 0.1 2.6 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) NPV_P10 PF05531.7 EAK88609.1 - 0.23 11.7 4.7 2.6 8.3 0.0 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein LTXXQ PF07813.7 EAK88609.1 - 0.48 10.9 5.6 0.65 10.4 0.2 2.9 3 0 0 3 3 3 0 LTXXQ motif family protein CENP-Q PF13094.1 EAK88609.1 - 0.59 10.1 26.4 0.27 11.2 2.7 3.2 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF972 PF06156.8 EAK88609.1 - 1.4 9.2 22.1 10 6.5 1.1 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF972) IncA PF04156.9 EAK88609.1 - 4.7 6.7 40.3 0.55 9.8 8.2 3.1 1 1 1 3 3 3 0 IncA protein DUF2400 PF09674.5 EAK88609.1 - 5.6 6.5 9.9 5.8 6.5 0.4 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2400) UPF0020 PF01170.13 EAK88610.1 - 0.0058 16.2 0.0 0.99 8.9 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Patched PF02460.13 EAK88611.1 - 3.8e-101 339.3 0.0 1.1e-100 337.8 0.0 1.7 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EAK88611.1 - 2.8e-22 78.8 7.3 2.8e-22 78.8 5.1 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 EAK88611.1 - 0.079 10.3 9.9 0.12 9.7 6.8 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family PapC_N PF13954.1 EAK88612.1 - 0.066 12.7 2.8 0.075 12.6 1.7 1.4 1 1 0 1 1 1 0 PapC N-terminal domain Maf PF02545.9 EAK88613.1 - 8.4e-32 109.8 0.2 1e-31 109.5 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein MxiM PF11441.3 EAK88613.1 - 0.017 15.1 0.6 0.086 12.9 0.0 2.3 1 1 1 2 2 2 0 Pilot protein MxiM CopK PF11525.3 EAK88614.1 - 0.055 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Copper resistance protein K ChpXY PF10216.4 EAK88614.1 - 0.096 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 CO2 hydration protein (ChpXY) GLE1 PF07817.8 EAK88614.1 - 5.7 5.7 6.6 4 6.3 1.2 2.1 2 0 0 2 2 2 0 GLE1-like protein GIY-YIG PF01541.19 EAK88615.1 - 4.1e-07 30.2 0.2 1.5e-06 28.4 0.0 2.2 2 1 0 2 2 2 1 GIY-YIG catalytic domain zf-RING_2 PF13639.1 EAK88615.1 - 0.0083 15.9 6.2 0.02 14.6 4.3 1.7 1 0 0 1 1 1 1 Ring finger domain DUF872 PF05915.7 EAK88616.1 - 4.6e-12 45.8 0.2 5.2e-12 45.6 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) RAMP4 PF06624.7 EAK88616.1 - 0.083 12.4 4.4 0.099 12.2 1.4 2.2 2 1 0 2 2 2 0 Ribosome associated membrane protein RAMP4 ABC2_membrane_3 PF12698.2 EAK88616.1 - 1.4 7.8 9.8 2 7.3 6.8 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein GCFC PF07842.7 EAK88618.1 - 2.5e-14 53.2 5.9 2.5e-14 53.2 4.1 2.0 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EAK88618.1 - 4.8e-09 35.8 0.9 1.1e-08 34.7 0.6 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EAK88618.1 - 0.1 12.4 1.2 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 DExH-box splicing factor binding site Hydrolase PF00702.21 EAK88619.1 - 2.4e-16 60.8 0.1 8.6e-11 42.6 0.2 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EAK88619.1 - 3.1e-15 55.8 1.3 3.3e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EAK88619.1 - 4.2e-13 49.8 0.0 2.8e-12 47.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Band_3_cyto PF07565.8 EAK88620.1 - 0.01 15.3 0.5 0.01 15.3 0.3 2.9 3 1 0 3 3 3 0 Band 3 cytoplasmic domain PAZ_siRNAbind PF12212.3 EAK88620.1 - 0.84 9.3 9.1 0.24 11.0 2.5 3.0 3 0 0 3 3 3 0 Piwi/Argonaute/Zwille siRNA-binding domain Ribosomal_L23 PF00276.15 EAK88621.1 - 0.58 10.1 4.6 0.93 9.4 1.1 2.2 1 1 0 2 2 2 0 Ribosomal protein L23 Solute_trans_a PF03619.11 EAK88622.1 - 2.4e-98 328.8 18.3 3.4e-98 328.3 12.7 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DEAD PF00270.24 EAK88623.1 - 2.2e-16 59.8 0.0 6.4e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK88623.1 - 1.9e-06 27.6 0.1 5.1e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UQ_con PF00179.21 EAK88624.1 - 5.1e-07 29.1 0.5 5.1e-07 29.1 0.4 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EAK88624.1 - 0.016 14.8 0.5 0.12 12.1 0.3 2.3 1 1 0 1 1 1 0 UEV domain IMCp PF12314.3 EAK88626.1 - 8.4e-11 41.8 50.6 7.5e-06 26.0 11.9 3.4 1 1 2 3 3 3 3 Inner membrane complex protein SieB PF14163.1 EAK88627.1 - 0.057 12.9 0.4 0.081 12.4 0.3 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B DAP10 PF07213.6 EAK88627.1 - 0.12 12.1 0.1 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 DAP10 membrane protein DUF202 PF02656.10 EAK88627.1 - 0.12 12.5 3.1 0.2 11.8 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) PMP22_Claudin PF00822.15 EAK88627.1 - 0.13 11.9 1.9 0.19 11.3 1.3 1.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF1469 PF07332.6 EAK88627.1 - 0.17 11.5 1.5 0.22 11.2 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) PsbX PF06596.6 EAK88627.1 - 0.26 10.9 6.2 0.42 10.3 0.7 2.3 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) EphA2_TM PF14575.1 EAK88627.1 - 0.32 11.3 1.9 0.55 10.6 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SAYSvFN PF10260.4 EAK88627.1 - 0.41 10.4 3.5 11 5.8 1.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) SdpI PF13630.1 EAK88627.1 - 1.7 8.4 6.5 2.7 7.7 4.5 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family tRNA_anti-codon PF01336.20 EAK88628.1 - 0.071 12.9 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain SNF2_N PF00176.18 EAK88629.1 - 3.6e-34 117.9 0.8 7.2e-34 116.9 0.6 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAK88629.1 - 2.5e-07 30.4 0.0 6.6e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain F-box PF00646.28 EAK88629.1 - 0.022 14.4 3.8 6.3 6.5 0.0 4.0 3 0 0 3 3 3 0 F-box domain DUF3336 PF11815.3 EAK88630.1 - 7.1e-34 116.3 2.2 1.8e-33 115.0 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EAK88630.1 - 8.9e-24 84.5 0.0 2.2e-23 83.2 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase SF-assemblin PF06705.6 EAK88632.1 - 2.2e-07 30.3 28.7 4.8e-07 29.1 13.6 2.6 2 1 0 2 2 2 2 SF-assemblin/beta giardin PAS_6 PF08348.6 EAK88632.1 - 0.012 15.2 1.4 0.012 15.2 1.0 2.0 2 1 1 3 3 3 0 YheO-like PAS domain Phage_GPO PF05929.6 EAK88632.1 - 0.32 10.2 8.6 0.15 11.3 0.1 2.4 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF947 PF06102.7 EAK88634.1 - 0.026 14.3 17.5 0.01 15.6 10.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF947) DUF1600 PF07667.6 EAK88635.1 - 0.13 12.4 4.0 0.24 11.5 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) EF-hand_7 PF13499.1 EAK88636.1 - 9.7e-26 89.7 18.7 2.1e-12 47.0 1.8 4.0 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EAK88636.1 - 7.1e-19 66.2 8.5 8e-06 24.9 0.1 5.1 4 0 0 4 4 4 4 EF hand EF-hand_1 PF00036.27 EAK88636.1 - 7.7e-16 56.1 20.1 7.9e-05 21.6 0.2 5.4 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EAK88636.1 - 5.1e-13 47.7 17.7 0.0025 17.5 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 EAK88636.1 - 2.5e-07 30.1 1.6 2.5e-05 23.7 0.3 6.1 6 1 1 7 7 7 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EAK88636.1 - 0.00036 20.5 1.8 0.04 13.9 0.3 3.4 1 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Myb_DNA-binding PF00249.26 EAK88637.1 - 3.5e-13 49.3 0.4 6e-13 48.6 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAK88637.1 - 0.0028 17.7 0.1 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain V-ATPase_H_N PF03224.9 EAK88638.1 - 1e-62 212.0 0.3 1.5e-62 211.5 0.2 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EAK88638.1 - 1.8e-45 153.7 0.8 4.5e-45 152.4 0.5 1.7 1 0 0 1 1 1 1 V-ATPase subunit H Arm_2 PF04826.8 EAK88638.1 - 8.7e-05 21.7 0.5 0.00057 19.0 0.0 2.3 2 0 0 2 2 2 1 Armadillo-like HEAT_2 PF13646.1 EAK88638.1 - 0.0022 18.2 0.1 0.89 9.8 0.0 3.9 4 1 0 4 4 4 1 HEAT repeats Arm PF00514.18 EAK88638.1 - 0.003 17.3 1.7 2.7 7.9 0.0 4.3 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat EF1_GNE PF00736.14 EAK88639.1 - 4.5e-27 93.5 2.0 4.5e-27 93.5 1.4 1.9 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EAK88639.1 - 0.011 15.9 7.2 0.011 15.9 5.0 2.6 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region YlbD_coat PF14071.1 EAK88639.1 - 0.072 13.1 2.4 0.42 10.6 0.3 2.3 2 0 0 2 2 2 0 Putative coat protein Stm1_N PF09598.5 EAK88639.1 - 0.16 12.7 4.1 0.39 11.4 2.9 1.6 1 0 0 1 1 1 0 Stm1 SURF2 PF05477.6 EAK88639.1 - 4.9 6.1 14.4 0.1 11.7 4.2 1.9 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) NUDIX_4 PF14815.1 EAK88640.1 - 0.0034 16.7 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain MIF4G PF02854.14 EAK88641.1 - 2.8e-31 108.5 5.8 7.5e-31 107.1 4.1 1.8 1 0 0 1 1 1 1 MIF4G domain DUF3647 PF12363.3 EAK88643.1 - 0.044 13.8 3.5 5.4 7.1 0.1 3.2 1 1 2 3 3 3 0 Phage protein EpsG PF14897.1 EAK88643.1 - 2.3 7.0 10.6 0.37 9.6 1.7 2.2 2 0 0 2 2 2 0 EpsG family Rad51 PF08423.6 EAK88644.1 - 9.7e-05 21.3 0.1 0.0011 17.8 0.0 2.1 2 0 0 2 2 2 1 Rad51 ABC_tran PF00005.22 EAK88644.1 - 0.0028 17.9 1.9 0.0028 17.9 1.3 2.2 2 1 0 2 2 2 1 ABC transporter AAA_25 PF13481.1 EAK88644.1 - 0.082 12.2 0.0 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain EF-hand_7 PF13499.1 EAK88645.1 - 4.9e-14 52.2 3.6 1.3e-09 38.0 0.5 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EAK88645.1 - 1.7e-13 48.7 0.4 7.9e-06 24.8 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 EAK88645.1 - 7.1e-12 44.1 1.1 1.5e-05 24.0 0.3 2.6 2 1 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EAK88645.1 - 3.6e-10 39.2 0.5 1e-05 25.0 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EAK88645.1 - 2.2e-08 33.2 1.1 0.00057 19.5 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EAK88645.1 - 1.1e-05 25.3 0.1 1.7e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region LXG PF04740.7 EAK88645.1 - 0.0016 18.3 0.1 0.0025 17.6 0.1 1.4 1 1 0 1 1 1 1 LXG domain of WXG superfamily Dockerin_1 PF00404.13 EAK88645.1 - 0.4 10.4 3.6 1.8 8.4 0.0 2.6 3 0 0 3 3 3 0 Dockerin type I repeat Haemagg_act PF05860.8 EAK88645.1 - 1 9.1 7.8 3.7 7.3 3.2 2.4 1 1 1 2 2 2 0 haemagglutination activity domain ABC_tran PF00005.22 EAK88646.1 - 1.1e-18 67.8 29.3 6.2e-12 45.9 0.0 4.4 3 1 0 3 3 3 2 ABC transporter AAA_29 PF13555.1 EAK88646.1 - 6.1e-07 28.8 1.1 0.019 14.5 0.0 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain Miro PF08477.8 EAK88646.1 - 8.4e-06 26.2 0.0 0.016 15.7 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EAK88646.1 - 9.3e-05 22.4 0.5 0.073 13.0 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain ABC_membrane PF00664.18 EAK88646.1 - 0.00015 21.2 5.5 0.00015 21.2 3.8 4.0 3 1 0 3 3 3 2 ABC transporter transmembrane region MMR_HSR1 PF01926.18 EAK88646.1 - 0.00026 20.9 5.8 0.31 11.0 0.3 3.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EAK88646.1 - 0.0005 20.2 0.5 1.2 9.3 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 EAK88646.1 - 0.0017 18.2 0.0 0.14 12.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EAK88646.1 - 0.0037 16.6 0.0 2.5 7.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EAK88646.1 - 0.0041 16.3 0.1 0.74 8.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EAK88646.1 - 0.0065 16.1 0.1 0.36 10.5 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EAK88646.1 - 0.014 15.1 0.1 0.44 10.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EAK88646.1 - 0.025 14.2 0.0 0.66 9.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EAK88646.1 - 0.035 13.5 0.0 5.1 6.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EAK88646.1 - 0.035 14.9 0.0 22 5.9 0.0 3.6 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EAK88646.1 - 0.052 12.4 0.0 5.2 5.8 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 EAK88646.1 - 0.13 12.0 0.0 0.13 12.0 0.0 4.7 4 1 0 4 4 4 0 Dynamin family FH2 PF02181.18 EAK88647.1 - 9e-18 64.2 14.9 9e-18 64.2 10.3 2.5 3 0 0 3 3 3 1 Formin Homology 2 Domain DEC-1_N PF04625.8 EAK88647.1 - 0.018 13.7 20.2 0.04 12.5 14.0 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region zf-B_box PF00643.19 EAK88648.1 - 2.8e-11 43.0 14.6 7.4e-07 28.9 1.0 2.9 2 0 0 2 2 2 2 B-box zinc finger PARP PF00644.15 EAK88648.1 - 0.0033 16.8 0.2 0.15 11.4 0.0 2.5 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Dicty_REP PF05086.7 EAK88651.1 - 0.0021 15.9 10.7 0.003 15.4 7.4 1.3 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Mitofilin PF09731.4 EAK88651.1 - 0.0042 15.8 3.5 0.0048 15.6 2.4 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein MSP1_C PF07462.6 EAK88651.1 - 0.0052 15.2 8.9 0.009 14.4 6.2 1.3 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus FLO_LFY PF01698.11 EAK88651.1 - 0.029 13.2 5.4 0.039 12.8 3.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein CAF-1_p150 PF11600.3 EAK88651.1 - 0.11 11.9 16.9 0.041 13.2 9.9 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Paramyxo_C PF01692.13 EAK88651.1 - 0.41 10.2 9.0 0.9 9.1 6.3 1.6 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Innate_immun PF12782.2 EAK88651.1 - 0.46 9.6 18.0 0.87 8.7 12.5 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Herpes_capsid PF06112.6 EAK88651.1 - 0.82 9.7 12.5 1.8 8.5 8.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Macoilin PF09726.4 EAK88651.1 - 1.3 7.2 14.8 1.6 6.9 10.3 1.2 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 EAK88651.1 - 1.9 7.8 15.8 10 5.4 11.0 2.1 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein bZIP_1 PF00170.16 EAK88652.1 - 0.0084 16.0 1.0 0.029 14.3 0.7 1.9 1 0 0 1 1 1 1 bZIP transcription factor ArsA_ATPase PF02374.10 EAK88652.1 - 0.019 14.0 1.7 0.038 13.0 1.2 1.5 1 0 0 1 1 1 0 Anion-transporting ATPase DUF1875 PF08961.5 EAK88652.1 - 0.071 12.4 1.1 0.14 11.4 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) Laminin_II PF06009.7 EAK88652.1 - 0.074 12.8 2.9 0.17 11.6 2.0 1.5 1 0 0 1 1 1 0 Laminin Domain II Fib_alpha PF08702.5 EAK88652.1 - 4.9 7.2 8.9 1 9.4 2.3 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sedlin_N PF04628.8 EAK88653.1 - 7.4e-25 87.3 0.0 9.2e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region MIP-T3 PF10243.4 EAK88655.1 - 0.00011 20.8 25.2 0.00019 20.0 17.5 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Zip PF02535.17 EAK88655.1 - 1.4 7.8 6.2 2.9 6.8 4.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SNF2_N PF00176.18 EAK88656.1 - 3.3e-76 255.9 1.0 3.3e-76 255.9 0.7 1.9 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAK88656.1 - 1.1e-16 60.3 0.0 4.9e-16 58.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3467 PF11950.3 EAK88657.1 - 0.013 15.5 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) DUF4615 PF15393.1 EAK88658.1 - 0.21 11.8 5.8 0.25 11.5 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) GST_C PF00043.20 EAK88660.1 - 0.00041 20.2 0.0 0.00087 19.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAK88660.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UBN2_3 PF14244.1 EAK88660.1 - 0.078 12.5 0.7 0.12 11.9 0.5 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Fe_hyd_lg_C PF02906.9 EAK88662.1 - 0.041 13.1 0.1 7.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain Bromodomain PF00439.20 EAK88663.1 - 0.00073 19.4 0.2 0.013 15.4 0.0 2.8 3 0 0 3 3 3 1 Bromodomain MRP-S31 PF15433.1 EAK88663.1 - 0.0022 17.4 2.2 0.0022 17.4 1.5 2.0 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S31 Spp-24 PF07448.6 EAK88663.1 - 0.025 14.5 0.7 0.025 14.5 0.5 1.9 2 0 0 2 2 2 0 Secreted phosphoprotein 24 (Spp-24) FAM60A PF15396.1 EAK88663.1 - 1.8 8.2 20.3 0.018 14.7 2.2 2.9 3 0 0 3 3 3 0 Protein Family FAM60A F-box-like PF12937.2 EAK88665.1 - 0.0024 17.5 0.7 0.017 14.8 0.1 2.5 2 0 0 2 2 2 1 F-box-like DUF1367 PF07105.6 EAK88665.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) DUF382 PF04037.8 EAK88670.1 - 1.5e-56 189.6 0.4 1.5e-56 189.6 0.3 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.11 EAK88670.1 - 7.4e-22 76.4 6.1 1.4e-21 75.5 4.2 1.5 1 0 0 1 1 1 1 PSP PrsW-protease PF13367.1 EAK88671.1 - 7.7e-14 51.3 18.3 9e-14 51.0 8.5 3.0 2 1 0 2 2 2 1 Protease prsW family ERGIC_N PF13850.1 EAK88671.1 - 0.36 10.8 5.1 2.9 7.9 0.2 2.9 2 1 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Dus PF01207.12 EAK88672.1 - 6.5e-38 130.3 0.0 3.8e-28 98.2 0.0 3.7 3 1 0 3 3 3 3 Dihydrouridine synthase (Dus) DUF4520 PF15016.1 EAK88672.1 - 0.095 12.2 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Nsp1_C PF05064.8 EAK88673.1 - 3e-13 49.4 9.5 2.5e-12 46.4 3.4 2.6 2 0 0 2 2 2 2 Nsp1-like C-terminal region Filament PF00038.16 EAK88673.1 - 0.0044 16.5 10.8 0.021 14.3 0.3 2.2 2 0 0 2 2 2 2 Intermediate filament protein CENP-F_leu_zip PF10473.4 EAK88673.1 - 3.1 7.6 11.6 4 7.3 2.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-HC5HC2H_2 PF13832.1 EAK88674.1 - 6.9e-16 58.2 16.1 4.1e-10 39.6 4.2 5.8 6 0 0 6 6 6 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EAK88674.1 - 5.2e-14 52.1 14.2 5.9e-10 39.1 1.5 5.8 6 0 0 6 6 6 2 PHD-like zinc-binding domain PHD PF00628.24 EAK88674.1 - 1.4e-05 24.6 21.8 0.00029 20.4 8.5 7.7 8 0 0 8 8 8 3 PHD-finger DUF1777 PF08648.7 EAK88676.1 - 0.00016 21.4 15.3 0.00023 20.9 10.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) RNA_pol_L_2 PF13656.1 EAK88676.1 - 0.06 12.7 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Macoilin PF09726.4 EAK88676.1 - 0.16 10.2 16.3 0.24 9.6 11.3 1.2 1 0 0 1 1 1 0 Transmembrane protein Ndc1_Nup PF09531.5 EAK88676.1 - 0.18 10.1 4.8 0.26 9.6 3.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.4 EAK88676.1 - 0.63 8.8 14.3 0.9 8.3 9.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain MIP-T3 PF10243.4 EAK88676.1 - 1.4 7.2 19.2 0.14 10.6 10.0 1.6 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Neur_chan_memb PF02932.11 EAK88676.1 - 2.3 8.0 4.7 3.5 7.4 3.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DNA_pol_viral_N PF00242.12 EAK88676.1 - 6.9 5.5 15.6 9 5.2 10.8 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain AP2 PF00847.15 EAK88677.1 - 1.5e-10 41.0 2.3 1.5e-10 41.0 1.6 1.9 2 0 0 2 2 2 1 AP2 domain DUF4407 PF14362.1 EAK88677.1 - 1.3 7.8 5.1 2.7 6.8 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tweety PF04906.8 EAK88677.1 - 1.8 6.8 5.6 4 5.7 3.9 1.5 1 0 0 1 1 1 0 Tweety DUF4557 PF15101.1 EAK88677.1 - 8.8 6.1 18.4 13 5.5 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) HTH_43 PF09904.4 EAK88678.1 - 0.007 16.1 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix DUF3139 PF11337.3 EAK88678.1 - 0.085 13.1 0.4 0.085 13.1 0.3 3.7 4 1 1 5 5 5 0 Protein of unknown function (DUF3139) Baculo_PEP_C PF04513.7 EAK88679.1 - 0.0025 17.6 1.8 0.0025 17.6 1.2 1.8 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 EAK88679.1 - 0.011 15.2 0.0 0.034 13.6 0.0 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain KIP1 PF07765.7 EAK88679.1 - 0.086 12.6 3.5 0.7 9.7 0.3 3.1 2 2 1 3 3 3 0 KIP1-like protein DUF1664 PF07889.7 EAK88679.1 - 0.27 11.0 4.3 0.51 10.1 2.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Duffy_binding PF05424.6 EAK88679.1 - 9.7 5.9 9.5 1.2 8.9 2.7 1.9 1 1 1 2 2 2 0 Duffy binding domain Telomerase_RBD PF12009.3 EAK88680.1 - 1.9e-32 112.0 7.7 1.9e-32 112.0 5.4 3.8 4 0 0 4 4 4 1 Telomerase ribonucleoprotein complex - RNA binding domain SDA1 PF05285.7 EAK88681.1 - 4.5e-31 108.3 45.1 4.9e-30 104.9 25.0 3.0 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EAK88681.1 - 3.8e-18 65.4 1.4 9.6e-18 64.2 0.1 2.4 2 0 0 2 2 2 1 NUC130/3NT domain Peptidase_C80 PF11713.3 EAK88683.1 - 0.0021 17.8 0.3 0.0047 16.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase C80 family Peptidase_S76 PF13611.1 EAK88683.1 - 0.0093 16.0 2.3 0.011 15.8 0.2 2.1 2 0 0 2 2 2 1 Serine peptidase of plant viral polyprotein, P1 IncA PF04156.9 EAK88683.1 - 7.8 6.0 24.3 1.5 8.3 0.2 2.3 1 1 1 2 2 2 0 IncA protein Rho_Binding PF08912.6 EAK88684.1 - 0.011 15.9 1.7 0.011 15.9 1.2 3.4 4 0 0 4 4 4 0 Rho Binding ZYG-11_interact PF05884.7 EAK88684.1 - 0.21 10.6 0.5 0.32 10.0 0.4 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 ACR_tran PF00873.14 EAK88684.1 - 0.29 8.4 3.4 0.38 8.0 2.4 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TPR_11 PF13414.1 EAK88687.1 - 3.6e-19 68.1 0.3 1e-11 44.2 0.0 3.7 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 EAK88687.1 - 1.6e-14 52.7 0.2 3.9e-05 23.0 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAK88687.1 - 1.3e-12 46.5 0.9 0.0027 17.5 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EAK88687.1 - 1.1e-07 31.1 0.8 1.8 8.5 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAK88687.1 - 4.6e-07 29.5 1.5 0.37 11.1 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAK88687.1 - 5.1e-07 29.5 3.7 0.059 13.3 0.5 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAK88687.1 - 1.9e-06 28.0 1.8 0.00049 20.3 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAK88687.1 - 2.4e-06 28.0 6.5 8.4e-05 23.1 0.2 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAK88687.1 - 0.0027 18.1 7.0 0.025 15.1 0.3 4.0 3 1 2 5 5 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAK88687.1 - 0.0032 17.1 1.5 5.5 7.0 0.0 5.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EAK88687.1 - 0.049 13.4 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF615 PF04751.9 EAK88688.1 - 0.0024 17.5 4.2 0.0064 16.1 2.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF615) FH2 PF02181.18 EAK88688.1 - 0.0045 15.9 2.1 0.0094 14.8 1.5 1.5 1 1 0 1 1 1 1 Formin Homology 2 Domain COG2 PF06148.6 EAK88688.1 - 0.064 13.1 2.8 0.14 12.0 0.8 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Pkinase PF00069.20 EAK88689.1 - 3.7e-07 29.5 0.0 7.2e-06 25.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain HSP70 PF00012.15 EAK88690.1 - 2.4e-55 187.6 1.0 1.2e-44 152.3 0.3 3.0 2 1 0 2 2 2 2 Hsp70 protein Mucin PF01456.12 EAK88691.1 - 0.0035 17.1 27.2 0.009 15.7 18.8 1.7 1 0 0 1 1 1 1 Mucin-like glycoprotein Nup54 PF13874.1 EAK88691.1 - 0.11 12.1 9.9 0.24 11.0 6.9 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 MGC-24 PF05283.6 EAK88691.1 - 0.69 9.6 19.9 1.6 8.4 13.8 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) PGM_PMM_III PF02880.11 EAK88693.1 - 9.6e-27 93.2 0.0 2.2e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.11 EAK88693.1 - 2.3e-26 91.9 0.0 4.5e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EAK88693.1 - 7.8e-13 48.6 0.2 3.2e-12 46.6 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EAK88693.1 - 2.4e-09 37.0 0.0 6.6e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EAK88694.1 - 1.2e-26 92.9 0.0 2.8e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.11 EAK88694.1 - 3.1e-26 91.5 0.0 4.7e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EAK88694.1 - 2.9e-12 46.8 0.0 8.9e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EAK88694.1 - 1.4e-09 37.7 0.0 3.8e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain LSM14 PF12701.2 EAK88695.1 - 4.3e-27 93.7 0.0 7.6e-27 92.9 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.1 EAK88695.1 - 9.6e-09 35.0 0.2 3.1e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Ataxin 2 SM domain FDF PF09532.5 EAK88695.1 - 2.8e-07 31.0 8.1 2.8e-07 31.0 5.6 2.2 2 1 0 2 2 2 1 FDF domain LSM PF01423.17 EAK88695.1 - 0.00019 20.9 0.0 0.00042 19.8 0.0 1.6 1 0 0 1 1 1 1 LSM domain DUF4403 PF14356.1 EAK88695.1 - 0.014 13.6 0.0 0.023 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) PGI PF00342.14 EAK88696.1 - 1.8e-164 547.7 0.0 2.2e-164 547.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase RabGAP-TBC PF00566.13 EAK88698.1 - 7e-38 130.2 4.4 7e-38 130.2 3.1 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SPAM PF02090.10 EAK88699.1 - 0.02 14.9 2.2 0.027 14.4 1.5 1.2 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein SYCE1 PF15233.1 EAK88699.1 - 0.15 11.9 5.7 0.39 10.6 3.9 1.7 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 UFD1 PF03152.9 EAK88700.1 - 1.4e-27 96.0 1.6 1.4e-27 96.0 1.1 2.0 2 0 0 2 2 2 1 Ubiquitin fusion degradation protein UFD1 DUF4191 PF13829.1 EAK88705.1 - 4.8 6.2 4.6 4.7 6.2 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) TSP_1 PF00090.14 EAK88706.1 - 1.3e-29 102.0 53.4 2.2e-10 40.4 3.9 4.5 4 0 0 4 4 4 4 Thrombospondin type 1 domain Kringle PF00051.13 EAK88706.1 - 4.8e-10 39.4 0.3 2.2e-09 37.2 0.2 2.2 1 0 0 1 1 1 1 Kringle domain HMG_box PF00505.14 EAK88707.1 - 2.8e-15 56.3 7.4 3.8e-15 55.9 3.2 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAK88707.1 - 3.6e-10 40.0 4.6 6.1e-10 39.3 3.2 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EAK88707.1 - 0.00089 18.9 0.3 0.0016 18.1 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF2398 PF09661.5 EAK88707.1 - 0.047 12.4 0.2 0.063 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) COX4 PF02936.9 EAK88707.1 - 0.063 13.0 0.2 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF4041 PF13250.1 EAK88708.1 - 0.1 12.1 0.5 0.16 11.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) POR PF01558.13 EAK88711.1 - 0.15 11.9 0.1 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Voldacs PF03517.8 EAK88712.1 - 1.7e-07 31.1 3.3 2.3e-07 30.7 2.3 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.3 EAK88712.1 - 0.0098 15.6 0.1 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 HATPase_c_5 PF14501.1 EAK88712.1 - 0.091 12.4 0.2 7.7 6.2 0.0 2.2 2 0 0 2 2 2 0 GHKL domain AAA PF00004.24 EAK88713.1 - 1.2e-52 177.5 0.1 1.9e-39 134.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAK88713.1 - 1.1e-10 41.8 0.1 0.0005 20.1 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EAK88713.1 - 2.7e-10 40.4 3.2 0.00059 19.9 0.1 4.9 3 2 1 4 4 3 2 AAA domain AAA_5 PF07728.9 EAK88713.1 - 5.9e-09 35.7 0.0 0.00027 20.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EAK88713.1 - 4.2e-07 29.0 0.0 0.018 13.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 EAK88713.1 - 9.6e-07 28.9 0.0 0.057 13.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 EAK88713.1 - 1.6e-06 27.7 1.5 0.00045 19.9 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EAK88713.1 - 5.8e-06 26.2 0.0 0.041 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EAK88713.1 - 7.6e-06 25.9 0.0 5.5e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EAK88713.1 - 1.6e-05 24.4 0.1 0.057 12.8 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.21 EAK88713.1 - 1.9e-05 24.2 0.1 0.088 12.2 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_33 PF13671.1 EAK88713.1 - 2.7e-05 24.0 0.0 0.0016 18.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EAK88713.1 - 3.6e-05 23.0 0.1 0.004 16.3 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EAK88713.1 - 4e-05 24.4 0.0 0.0049 17.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EAK88713.1 - 4.6e-05 22.8 2.9 0.63 9.4 0.1 3.7 2 2 0 3 3 3 2 AAA domain KaiC PF06745.8 EAK88713.1 - 5.5e-05 22.3 0.1 0.13 11.3 0.0 2.6 2 0 0 2 2 2 2 KaiC DAP3 PF10236.4 EAK88713.1 - 6.5e-05 22.0 0.1 0.021 13.7 0.0 2.7 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.1 EAK88713.1 - 0.00013 22.2 0.1 0.0092 16.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EAK88713.1 - 0.00015 21.4 5.8 0.12 12.0 0.0 3.8 5 0 0 5 5 4 2 NACHT domain ABC_tran PF00005.22 EAK88713.1 - 0.00016 21.9 0.7 0.023 14.9 0.1 2.8 2 0 0 2 2 2 1 ABC transporter RuvB_N PF05496.7 EAK88713.1 - 0.0002 20.5 0.1 0.035 13.1 0.0 2.7 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus NB-ARC PF00931.17 EAK88713.1 - 0.0007 18.5 0.4 0.25 10.1 0.0 2.9 2 1 0 3 3 3 1 NB-ARC domain PhoH PF02562.11 EAK88713.1 - 0.0013 17.9 0.1 0.55 9.4 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.1 EAK88713.1 - 0.0021 17.6 0.0 0.062 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EAK88713.1 - 0.0025 17.8 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EAK88713.1 - 0.0027 16.7 0.0 0.1 11.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 EAK88713.1 - 0.003 17.1 1.5 0.97 8.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EAK88713.1 - 0.0036 16.9 0.3 0.53 9.9 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EAK88713.1 - 0.0053 16.4 0.4 4.9 6.7 0.0 3.1 2 1 1 3 3 3 0 Archaeal ATPase Torsin PF06309.6 EAK88713.1 - 0.0058 16.5 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 1 Torsin Sigma54_activ_2 PF14532.1 EAK88713.1 - 0.0059 16.6 0.0 4.5 7.3 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 EAK88713.1 - 0.0067 16.0 0.0 0.051 13.1 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EAK88713.1 - 0.0098 15.0 0.1 0.74 8.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Parvo_NS1 PF01057.12 EAK88713.1 - 0.015 14.1 0.1 0.39 9.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EAK88713.1 - 0.035 13.0 0.1 0.2 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KTI12 PF08433.5 EAK88713.1 - 0.036 13.2 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 1 0 Chromatin associated protein KTI12 MobB PF03205.9 EAK88713.1 - 0.036 13.7 0.1 12 5.5 0.0 3.4 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EAK88713.1 - 0.05 13.1 0.1 3.2 7.1 0.0 2.9 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.1 EAK88713.1 - 0.066 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EAK88713.1 - 0.099 12.4 0.1 0.71 9.6 0.0 2.4 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 EAK88713.1 - 0.1 12.1 0.3 1.8 8.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ribosomal_S9 PF00380.14 EAK88714.1 - 4.2e-34 117.4 0.1 4.8e-34 117.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF2419 PF10343.4 EAK88714.1 - 0.044 13.0 0.0 0.059 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) DUF630 PF04783.7 EAK88714.1 - 0.091 12.6 0.2 7.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF630) zf-RING_2 PF13639.1 EAK88716.1 - 1.2e-06 28.1 9.7 3.4e-06 26.7 6.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAK88716.1 - 1.9e-06 27.8 5.1 6.1e-06 26.2 3.5 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EAK88716.1 - 0.00074 19.4 6.2 0.002 18.0 4.3 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 EAK88716.1 - 0.0018 18.3 8.6 0.0046 16.9 5.9 1.8 1 0 0 1 1 1 1 RING-variant domain zf-Apc11 PF12861.2 EAK88716.1 - 0.0029 17.4 2.9 0.0073 16.1 2.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EAK88716.1 - 0.1 12.6 11.3 0.29 11.1 7.8 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAK88716.1 - 0.17 11.5 11.3 0.6 9.8 7.8 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EAK88716.1 - 0.17 11.9 5.3 0.53 10.3 3.7 1.9 1 0 0 1 1 1 0 RING-like domain KH_1 PF00013.24 EAK88717.1 - 0.00012 21.6 0.1 0.0003 20.3 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EAK88717.1 - 0.0014 18.1 0.0 0.0044 16.6 0.0 1.8 1 0 0 1 1 1 1 KH domain zf-C3HC PF07967.8 EAK88718.1 - 0.0023 17.6 0.3 0.0034 17.1 0.2 1.2 1 0 0 1 1 1 1 C3HC zinc finger-like Cbl_N PF02262.11 EAK88718.1 - 0.075 12.7 0.1 0.096 12.4 0.1 1.1 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 WD40 PF00400.27 EAK88719.1 - 4.3e-38 127.8 39.7 1.3e-10 40.6 0.5 12.4 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.7 EAK88719.1 - 1.4e-05 24.9 0.1 2.7e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Lactonase PF10282.4 EAK88719.1 - 0.006 15.7 0.1 0.58 9.1 0.0 3.6 5 0 0 5 5 5 1 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.6 EAK88719.1 - 0.056 12.3 0.1 12 4.7 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) DUF4279 PF14106.1 EAK88720.1 - 2.2 8.1 6.3 2.1 8.2 0.4 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4279) Prefoldin_2 PF01920.15 EAK88720.1 - 5.2 6.8 35.6 0.27 11.0 0.1 6.2 5 1 2 7 7 7 0 Prefoldin subunit Lip_prot_lig_C PF10437.4 EAK88720.1 - 5.5 6.7 10.4 0.47 10.1 0.3 3.9 3 1 1 4 4 4 0 Bacterial lipoate protein ligase C-terminus Val_tRNA-synt_C PF10458.4 EAK88720.1 - 10 6.3 10.7 9.7 6.3 0.8 4.3 4 0 0 4 4 4 0 Valyl tRNA synthetase tRNA binding arm ER_lumen_recept PF00810.13 EAK88721.1 - 1.5e-37 129.3 7.1 1.5e-37 129.3 4.9 2.3 2 0 0 2 2 2 1 ER lumen protein retaining receptor EpuA PF11772.3 EAK88721.1 - 0.056 12.8 0.2 0.16 11.4 0.1 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta PsbH PF00737.15 EAK88721.1 - 0.097 12.2 0.4 0.97 9.0 0.0 2.5 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein BPL_LplA_LipB PF03099.14 EAK88722.1 - 2.2e-10 40.5 0.0 5.2e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Peptidase_M16_C PF05193.16 EAK88724.1 - 4.3e-13 49.3 0.1 1.4e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EAK88724.1 - 0.0024 17.6 0.1 0.005 16.6 0.1 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Sec63 PF02889.11 EAK88725.1 - 2.2e-108 362.2 18.7 1.8e-68 231.1 1.5 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EAK88725.1 - 1e-51 174.7 0.0 4.7e-25 88.0 0.0 3.0 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EAK88725.1 - 4.2e-14 52.7 13.4 4.1e-08 33.2 0.0 3.8 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EAK88725.1 - 3.2e-13 49.3 0.0 2.7e-05 23.9 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain PhoH PF02562.11 EAK88725.1 - 0.00021 20.5 0.0 0.31 10.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein T2SE PF00437.15 EAK88725.1 - 0.0023 16.8 0.0 0.39 9.5 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.1 EAK88725.1 - 0.0064 16.2 0.0 2.5 7.9 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 EAK88725.1 - 0.093 11.8 0.0 7.2 5.7 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI dCMP_cyt_deam_1 PF00383.17 EAK88726.1 - 8.7e-28 95.9 2.6 1.4e-27 95.3 1.8 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region THUMP PF02926.12 EAK88727.1 - 7.7e-05 22.5 0.0 0.00038 20.3 0.0 2.4 1 1 0 1 1 1 1 THUMP domain SYF2 PF08231.7 EAK88728.1 - 1.9e-12 47.5 17.8 1.9e-12 47.5 12.3 2.2 1 1 1 2 2 2 1 SYF2 splicing factor Lectin_N PF03954.9 EAK88729.1 - 0.89 8.9 4.3 3.1 7.2 2.7 2.1 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain SMC_N PF02463.14 EAK88730.1 - 6.8e-58 195.4 21.4 1.2e-56 191.4 14.8 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EAK88730.1 - 1.8e-18 67.6 6.8 1.8e-18 67.6 4.7 7.3 2 2 2 4 4 2 1 AAA domain SMC_hinge PF06470.8 EAK88730.1 - 7.9e-18 64.5 0.0 3.6e-17 62.4 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EAK88730.1 - 2.2e-11 44.2 30.4 2e-09 37.8 2.3 6.2 1 1 4 6 6 3 2 AAA domain AAA_29 PF13555.1 EAK88730.1 - 4.2e-07 29.3 0.0 1.1e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EAK88730.1 - 5.9e-05 22.9 0.0 0.00025 20.9 0.0 2.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 EAK88730.1 - 0.0035 17.3 1.9 0.38 10.7 0.0 3.7 3 0 0 3 3 3 1 AAA ATPase domain IncA PF04156.9 EAK88730.1 - 0.0043 16.6 5.1 0.0043 16.6 3.5 8.5 4 3 3 7 7 4 2 IncA protein AAA_25 PF13481.1 EAK88730.1 - 0.019 14.3 0.0 0.12 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EAK88730.1 - 0.056 13.7 0.0 0.056 13.7 0.0 6.9 5 3 0 5 5 3 0 ABC transporter AAA_17 PF13207.1 EAK88730.1 - 0.1 13.3 0.0 0.1 13.3 0.0 5.3 2 2 0 3 3 3 0 AAA domain Reo_sigmaC PF04582.7 EAK88730.1 - 3.8 6.6 25.4 2.1 7.4 0.2 5.1 3 2 1 5 5 5 0 Reovirus sigma C capsid protein Neurochondrin PF05536.6 EAK88732.1 - 0.015 13.6 0.7 0.044 12.0 0.1 2.1 2 1 0 2 2 2 0 Neurochondrin DUF4473 PF14747.1 EAK88732.1 - 0.03 14.5 0.0 7.9 6.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) DUF4201 PF13870.1 EAK88733.1 - 0.011 15.1 9.1 0.011 15.1 6.3 5.1 3 1 2 5 5 5 0 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 EAK88733.1 - 0.013 14.7 0.8 1.2 8.2 0.1 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FUSC PF04632.7 EAK88733.1 - 2.8 6.2 3.0 4 5.7 2.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Lipoprotein_20 PF13942.1 EAK88733.1 - 2.9 7.4 18.4 3.3 7.2 7.2 2.9 2 1 0 2 2 2 0 YfhG lipoprotein IncA PF04156.9 EAK88733.1 - 5.4 6.5 45.6 0.033 13.7 9.7 3.7 3 1 1 4 4 4 0 IncA protein Hydrolase PF00702.21 EAK88734.1 - 3.3e-15 57.0 1.6 6.2e-10 39.8 0.8 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EAK88734.1 - 6.7e-13 48.1 0.0 2.4e-12 46.3 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EAK88734.1 - 9.4e-09 35.7 0.0 6e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAK88734.1 - 0.00036 20.4 0.1 0.0019 18.1 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Nuc_sug_transp PF04142.10 EAK88735.1 - 5e-57 192.8 8.8 1e-56 191.7 6.1 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EAK88735.1 - 9.8e-10 38.2 23.4 3.8e-07 29.8 4.3 2.7 2 1 1 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 EAK88735.1 - 4e-07 30.1 7.1 4e-07 30.1 4.9 2.8 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EAK88735.1 - 1.8e-05 24.9 29.1 2.5e-05 24.4 5.1 3.4 2 2 1 3 3 3 2 Multidrug resistance efflux transporter UAA PF08449.6 EAK88735.1 - 0.0019 17.2 12.8 0.0034 16.3 8.9 1.5 1 1 0 1 1 1 1 UAA transporter family TauE PF01925.14 EAK88735.1 - 0.0034 16.8 3.5 0.0034 16.8 2.4 3.6 2 2 0 3 3 3 1 Sulfite exporter TauE/SafE Nuc_sug_transp PF04142.10 EAK88736.1 - 1e-51 175.3 22.7 1.3e-31 109.5 1.0 2.7 3 0 0 3 3 3 2 Nucleotide-sugar transporter EamA PF00892.15 EAK88736.1 - 1.7e-07 31.2 32.5 3.4e-06 27.1 6.5 3.1 2 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EAK88736.1 - 2.7e-07 30.7 4.5 2.7e-07 30.7 3.1 3.3 3 1 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EAK88736.1 - 4e-06 26.5 10.7 4e-06 26.5 7.4 3.2 1 1 1 2 2 2 1 Triose-phosphate Transporter family UPF0546 PF10639.4 EAK88736.1 - 3 7.7 14.8 1.2 9.0 2.2 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0546 TcdB_N PF12918.2 EAK88746.1 - 0.024 14.6 0.5 0.024 14.6 0.3 2.1 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain TINF2_N PF14973.1 EAK88749.1 - 0.62 10.1 4.4 0.26 11.3 0.6 2.2 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus GMC_oxred_N PF00732.14 EAK88750.1 - 1.8e-20 73.2 0.3 1.3e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EAK88750.1 - 1.8e-10 41.2 0.0 1e-09 38.8 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAK88750.1 - 4.8e-06 25.7 0.6 7.8e-06 25.0 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAK88750.1 - 0.00011 22.1 0.2 0.00024 21.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAK88750.1 - 0.00012 22.0 1.3 0.00029 20.7 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAK88750.1 - 0.00027 19.9 0.5 0.00042 19.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EAK88750.1 - 0.0059 15.1 0.1 0.0088 14.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EAK88750.1 - 0.0061 15.5 0.3 0.0086 15.0 0.2 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 EAK88750.1 - 0.009 14.9 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.11 EAK88750.1 - 0.017 14.5 0.2 0.032 13.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EAK88750.1 - 0.035 14.5 0.5 0.035 14.5 0.3 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAK88750.1 - 0.062 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EAK88750.1 - 0.23 11.0 0.2 0.41 10.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EAK88750.1 - 1 8.3 3.0 0.81 8.6 1.1 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase AIG2_2 PF13772.1 EAK88751.1 - 0.1 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AIG2-like family Peptidase_M24 PF00557.19 EAK88752.1 - 1.5e-38 132.4 0.0 1.9e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF2407 PF10302.4 EAK88752.1 - 4.2 7.6 5.8 23 5.2 0.1 2.4 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF489 PF04356.7 EAK88754.1 - 0.13 11.7 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) RINGv PF12906.2 EAK88756.1 - 1e-11 44.7 6.8 1.4e-11 44.2 4.7 1.2 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EAK88756.1 - 0.27 11.0 6.9 4.3 7.2 5.5 2.0 1 1 1 2 2 2 0 Ring finger domain FANCL_C PF11793.3 EAK88756.1 - 0.85 9.6 5.1 1.6 8.7 3.6 1.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 EAK88756.1 - 2.3 7.9 5.2 4.9 6.9 3.6 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PseudoU_synth_2 PF00849.17 EAK88757.1 - 2.3e-22 79.5 0.1 3.8e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EAK88757.1 - 0.00084 18.7 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain AA_kinase PF00696.23 EAK88758.1 - 1.4e-35 122.9 0.2 2.3e-35 122.2 0.2 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EAK88758.1 - 1.2e-14 53.7 0.7 2.1e-14 52.9 0.1 1.7 2 0 0 2 2 2 1 PUA domain Shadoo PF14999.1 EAK88758.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Pkinase PF00069.20 EAK88759.1 - 3.3e-44 151.0 0.3 7.5e-44 149.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK88759.1 - 5e-31 107.7 0.0 9.6e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAK88759.1 - 0.0013 18.5 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EAK88759.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Dopey_N PF04118.9 EAK88763.1 - 2.2e-106 355.1 1.2 2.2e-106 355.1 0.9 3.6 3 0 0 3 3 3 2 Dopey, N-terminal MA3 PF02847.12 EAK88764.1 - 1.1e-20 73.4 6.3 2.9e-09 36.6 0.1 3.9 4 0 0 4 4 4 3 MA3 domain PPDK_N PF01326.14 EAK88766.1 - 3e-18 65.9 0.0 4e-17 62.2 0.0 3.1 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain C2 PF00168.25 EAK88767.1 - 1.6e-23 82.3 2.4 0.00045 20.0 0.0 6.4 6 0 0 6 6 6 5 C2 domain DnaJ PF00226.26 EAK88768.1 - 8.5e-19 67.0 1.3 8.5e-19 67.0 0.9 2.3 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.26 EAK88768.1 - 5.2e-10 39.2 0.1 0.00014 21.8 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAK88768.1 - 0.00059 19.8 12.7 0.0093 16.0 0.2 3.8 3 1 0 3 3 3 2 Myb-like DNA-binding domain DUF106 PF01956.11 EAK88768.1 - 3.8 7.0 12.5 0.3 10.6 2.0 3.0 3 0 0 3 3 3 0 Integral membrane protein DUF106 Cyclin PF08613.6 EAK88769.1 - 1.5e-26 93.6 1.5 2e-26 93.1 0.6 1.6 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.18 EAK88769.1 - 0.00044 19.8 0.5 0.001 18.6 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain PP2C PF00481.16 EAK88770.1 - 5.9e-14 52.0 0.0 1.3e-13 50.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EAK88770.1 - 0.00011 21.7 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C TSC22 PF01166.13 EAK88770.1 - 0.12 12.4 1.2 0.27 11.2 0.8 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family PA26 PF04636.8 EAK88772.1 - 1.3e-27 96.5 0.9 5.6e-22 78.0 0.0 2.4 2 0 0 2 2 2 2 PA26 p53-induced protein (sestrin) RNA_polI_A14 PF08203.6 EAK88772.1 - 0.078 13.2 0.6 3.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 TcdB_N PF12918.2 EAK88774.1 - 7.5 6.7 17.3 2.3 8.3 0.4 4.4 3 1 3 6 6 6 0 TcdB toxin N-terminal helical domain RPN7 PF10602.4 EAK88775.1 - 1.4e-46 158.1 1.4 2.4e-46 157.3 0.9 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EAK88775.1 - 3.4e-14 53.0 1.4 9.3e-14 51.6 1.0 1.7 1 0 0 1 1 1 1 PCI domain NGP1NT PF08153.7 EAK88777.1 - 4.9e-38 130.0 2.2 9.8e-38 129.0 1.5 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EAK88777.1 - 1.6e-19 69.9 0.2 5.7e-15 55.2 0.0 2.8 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EAK88777.1 - 4.7e-06 25.9 0.0 7.6e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EAK88777.1 - 0.0001 21.5 0.0 0.00021 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 EAK88777.1 - 0.00011 21.4 0.1 0.23 10.6 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.18 EAK88777.1 - 0.026 14.3 6.0 1.1 9.1 0.1 3.6 3 1 1 4 4 4 0 Dynamin family GTP_EFTU PF00009.22 EAK88777.1 - 0.088 12.2 0.1 36 3.7 0.0 3.4 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain DUF1620 PF07774.8 EAK88778.1 - 1.3e-40 138.9 15.5 3.9e-40 137.4 10.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) HMG_box PF00505.14 EAK88779.1 - 0.019 15.2 0.0 7.2 6.9 0.0 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box PFK PF00365.15 EAK88781.1 - 2.7e-35 121.7 0.0 7.2e-24 84.2 0.0 2.3 2 0 0 2 2 2 2 Phosphofructokinase Tfb2 PF03849.9 EAK88784.1 - 2.2e-42 145.0 5.5 2.1e-21 75.9 0.0 3.2 2 1 1 3 3 3 3 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EAK88784.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain PRP1_N PF06424.7 EAK88784.1 - 0.073 13.3 1.8 0.16 12.2 1.3 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF384 PF04064.8 EAK88785.1 - 3.8e-17 61.6 0.2 9.6e-17 60.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF383 PF04063.9 EAK88785.1 - 1.2e-11 44.5 6.5 3.8e-08 33.1 0.9 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF383) CagY_M PF07337.6 EAK88785.1 - 0.096 12.1 0.2 0.26 10.8 0.2 1.7 1 0 0 1 1 1 0 DC-EC Repeat PLATZ PF04640.9 EAK88786.1 - 0.0024 18.0 2.0 0.0029 17.7 0.1 2.1 2 0 0 2 2 2 1 PLATZ transcription factor DUF3228 PF11539.3 EAK88787.1 - 2.9e-83 277.8 0.1 3.3e-83 277.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) DUF4261 PF14080.1 EAK88787.1 - 0.019 14.7 0.1 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) A1_Propeptide PF07966.7 EAK88787.1 - 0.35 10.7 1.9 1.1 9.1 0.0 2.5 3 0 0 3 3 3 0 A1 Propeptide EF-hand_8 PF13833.1 EAK88788.1 - 5e-06 26.0 0.5 9.8e-06 25.1 0.3 1.5 1 0 0 1 1 1 1 EF-hand domain pair COPI_assoc PF08507.5 EAK88788.1 - 0.00032 20.3 5.3 0.00069 19.3 3.6 1.6 1 1 0 1 1 1 1 COPI associated protein EF-hand_1 PF00036.27 EAK88788.1 - 0.0015 17.6 0.2 0.0032 16.6 0.1 1.6 1 0 0 1 1 1 1 EF hand DUF4383 PF14325.1 EAK88788.1 - 0.011 15.6 3.9 0.016 15.1 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) Cg6151-P PF10233.4 EAK88788.1 - 0.015 15.2 0.3 0.033 14.1 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P EF-hand_6 PF13405.1 EAK88788.1 - 0.019 14.7 0.3 0.051 13.4 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 EAK88788.1 - 0.08 13.0 0.5 0.16 12.1 0.4 1.4 1 0 0 1 1 1 0 EF-hand domain pair ATP-synt_C PF00137.16 EAK88788.1 - 0.64 9.9 4.2 0.74 9.7 0.2 2.3 2 0 0 2 2 2 0 ATP synthase subunit C Wzy_C PF04932.10 EAK88788.1 - 0.84 9.4 6.3 6 6.6 4.4 2.2 1 1 0 1 1 1 0 O-Antigen ligase COPI_assoc PF08507.5 EAK88789.1 - 2.7e-06 27.1 0.2 3.6e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 COPI associated protein EF-hand_8 PF13833.1 EAK88789.1 - 0.064 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair MORN PF02493.15 EAK88790.1 - 8e-44 144.8 72.6 1.1e-07 31.1 1.3 10.3 10 0 0 10 10 10 9 MORN repeat V-SNARE_C PF12352.3 EAK88791.1 - 0.035 14.1 1.9 0.071 13.1 1.3 1.6 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Syntaxin_2 PF14523.1 EAK88791.1 - 0.037 14.0 8.8 5.6 7.0 6.1 2.2 1 1 0 1 1 1 0 Syntaxin-like protein Sialidase PF02973.11 EAK88791.1 - 0.048 12.6 10.4 0.17 10.8 7.2 1.7 1 1 0 1 1 1 0 Sialidase, N-terminal domain DUF3519 PF12033.3 EAK88791.1 - 0.069 13.3 2.9 0.13 12.4 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) Sec20 PF03908.8 EAK88791.1 - 0.36 10.5 6.6 0.13 11.9 2.2 1.9 2 0 0 2 2 2 0 Sec20 zf-MIZ PF02891.15 EAK88793.1 - 1.1e-17 63.2 1.8 1.1e-17 63.2 1.2 2.7 3 0 0 3 3 3 1 MIZ/SP-RING zinc finger PHD PF00628.24 EAK88793.1 - 1.9e-06 27.4 13.1 8.5e-06 25.3 3.1 3.4 2 1 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 EAK88793.1 - 0.00047 19.8 6.6 0.00073 19.2 3.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Rho_N PF07498.7 EAK88793.1 - 0.014 15.1 0.3 0.032 13.9 0.2 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Vps39_2 PF10367.4 EAK88793.1 - 0.031 14.4 1.2 0.13 12.3 0.8 2.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 C1_1 PF00130.17 EAK88793.1 - 0.54 10.0 9.5 0.032 13.9 2.2 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CENP-C_C PF11699.3 EAK88794.1 - 0.0021 17.9 1.2 0.0036 17.2 0.9 1.5 1 1 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EAK88794.1 - 0.0034 16.8 0.0 0.0053 16.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain chaperone_DMP PF10448.4 EAK88794.1 - 0.068 13.0 0.3 0.088 12.7 0.2 1.3 1 0 0 1 1 1 0 20S proteasome chaperone RabGAP-TBC PF00566.13 EAK88796.1 - 2.7e-10 40.1 4.9 2.7e-10 40.1 3.4 5.2 5 1 1 6 6 6 3 Rab-GTPase-TBC domain NTP_transferase PF00483.18 EAK88798.1 - 6.3e-40 137.0 0.0 9e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EAK88798.1 - 6.6e-10 38.0 15.5 1.1e-07 30.9 2.8 3.3 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EAK88798.1 - 4.8e-07 29.9 0.0 6.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EAK88798.1 - 2.2e-05 23.9 1.9 2.2e-05 23.9 1.3 3.2 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Ipi1_N PF12333.3 EAK88799.1 - 0.0027 17.6 0.0 0.012 15.5 0.0 2.1 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.2 EAK88799.1 - 0.078 13.3 3.3 0.27 11.6 0.1 3.2 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Thioredoxin_6 PF13848.1 EAK88800.1 - 3.5e-07 30.2 0.6 0.081 12.7 0.1 3.3 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.15 EAK88800.1 - 0.00019 21.0 0.0 0.074 12.7 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin zf-RING_5 PF14634.1 EAK88801.1 - 4.6e-07 29.4 5.2 1.1e-06 28.2 3.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAK88801.1 - 4.2e-06 26.6 8.9 9.9e-06 25.4 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAK88801.1 - 4.8e-06 26.1 4.6 1.2e-05 24.9 3.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EAK88801.1 - 8.2e-06 25.3 7.8 1.7e-05 24.3 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAK88801.1 - 8.2e-06 25.5 5.7 1.6e-05 24.6 3.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EAK88801.1 - 5.4e-05 22.7 4.1 0.00012 21.6 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAK88801.1 - 0.00014 21.6 9.0 0.00032 20.5 6.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 EAK88801.1 - 0.035 13.6 5.5 0.074 12.5 3.8 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger SWIRM PF04433.12 EAK88802.1 - 3.2e-36 123.2 1.8 7.9e-36 122.0 0.1 2.5 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 EAK88802.1 - 7.4e-09 35.5 0.0 2.7e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAK88802.1 - 5.3e-07 29.5 0.0 1.5e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Troponin PF00992.15 EAK88802.1 - 0.032 14.3 6.0 0.11 12.6 4.2 2.0 1 0 0 1 1 1 0 Troponin DUF1662 PF07878.6 EAK88802.1 - 0.048 13.4 0.1 0.23 11.2 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1662) ORC4_C PF14629.1 EAK88803.1 - 0.11 11.8 1.9 0.088 12.1 0.1 1.7 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus HALZ PF02183.13 EAK88804.1 - 0.018 14.7 0.8 0.07 12.8 0.6 2.1 1 0 0 1 1 1 0 Homeobox associated leucine zipper Nop PF01798.13 EAK88804.1 - 0.038 13.2 0.0 0.096 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative snoRNA binding domain CBFD_NFYB_HMF PF00808.18 EAK88806.1 - 0.00027 20.9 3.3 0.00086 19.3 2.3 1.8 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1704 PF08014.6 EAK88806.1 - 0.023 13.7 0.3 0.025 13.5 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) DUF106 PF01956.11 EAK88806.1 - 0.032 13.7 1.1 0.038 13.5 0.8 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 Flag1_repress PF03614.8 EAK88806.1 - 0.073 12.6 0.1 0.086 12.3 0.1 1.1 1 0 0 1 1 1 0 Repressor of phase-1 flagellin ING PF12998.2 EAK88807.1 - 7.1e-12 45.5 4.5 7.1e-12 45.5 3.1 2.4 1 1 2 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding DUF1087 PF06465.8 EAK88807.1 - 0.18 11.7 1.8 0.28 11.1 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) PHD PF00628.24 EAK88807.1 - 3.4 7.4 16.1 8.7 6.1 11.1 1.7 1 1 0 1 1 1 0 PHD-finger DDOST_48kD PF03345.9 EAK88808.1 - 4.7e-120 400.9 8.7 5.5e-120 400.7 6.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF365 PF04033.7 EAK88808.1 - 0.12 12.3 0.8 0.23 11.4 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Metallophos PF00149.23 EAK88809.1 - 1.1e-21 77.1 0.5 2.8e-21 75.8 0.3 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_8 PF13833.1 EAK88809.1 - 1.8e-12 46.6 0.1 2.1e-09 36.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EAK88809.1 - 1.3e-11 42.9 1.5 0.00074 18.6 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EAK88809.1 - 3.1e-11 43.2 6.2 1.6e-05 24.9 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EAK88809.1 - 1.3e-09 37.1 0.2 0.0064 16.2 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EAK88809.1 - 0.011 15.1 0.1 3.3 7.2 0.0 2.9 3 0 0 3 3 3 0 EF hand L_lactis_RepB_C PF06430.7 EAK88810.1 - 0.7 9.9 5.0 0.65 10.0 0.4 2.3 2 1 0 2 2 2 0 Lactococcus lactis RepB C-terminus MCM PF00493.18 EAK88811.1 - 9e-113 376.4 0.7 3.6e-112 374.4 0.1 2.1 2 1 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EAK88811.1 - 8.7e-19 68.1 0.0 3.8e-18 66.1 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EAK88811.1 - 2.8e-07 29.9 0.1 7.5e-05 21.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EAK88811.1 - 0.019 14.6 0.0 0.14 11.9 0.0 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EAK88811.1 - 0.022 14.2 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 EAK88811.1 - 0.022 14.9 0.0 0.091 12.9 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EAK88811.1 - 0.026 14.1 0.0 0.076 12.6 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAK88811.1 - 0.098 12.8 0.7 3.3 7.8 0.1 3.5 3 1 0 3 3 3 0 AAA domain Vps26 PF03643.10 EAK88812.1 - 4.3e-96 320.9 2.3 5.1e-96 320.6 1.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EAK88812.1 - 0.014 15.2 0.9 8.4 6.2 0.0 3.7 2 2 2 4 4 4 0 Arrestin (or S-antigen), N-terminal domain zf-Mss51 PF13824.1 EAK88813.1 - 0.043 13.6 0.4 11 6.0 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn-ribbon_8 PF09723.5 EAK88813.1 - 0.063 13.2 0.7 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Yippee-Mis18 PF03226.9 EAK88813.1 - 0.085 12.9 1.7 0.15 12.1 1.2 1.4 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.7 EAK88813.1 - 0.24 10.7 2.9 2.2 7.6 2.0 2.5 1 1 0 1 1 1 0 TFIIB zinc-binding zf-C2H2_4 PF13894.1 EAK88813.1 - 0.52 10.7 0.3 0.52 10.7 0.2 2.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-B_box PF00643.19 EAK88813.1 - 0.78 9.6 4.3 16 5.5 0.7 2.5 2 0 0 2 2 2 0 B-box zinc finger LIM PF00412.17 EAK88813.1 - 6.7 6.8 7.8 2.5 8.2 0.9 2.9 2 2 1 3 3 3 0 LIM domain EGF_CA PF07645.10 EAK88814.1 - 2.1e-23 82.0 75.6 1.8e-11 43.8 3.4 7.3 6 0 0 6 6 6 4 Calcium-binding EGF domain cEGF PF12662.2 EAK88814.1 - 6.1e-18 64.1 31.8 5e-07 29.2 0.6 7.2 6 0 0 6 6 6 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 EAK88814.1 - 2.1e-07 30.9 71.6 1.3e-05 25.1 6.9 7.4 7 1 1 8 8 8 5 Coagulation Factor Xa inhibitory site PAN_4 PF14295.1 EAK88814.1 - 3.8e-06 26.4 0.1 3.8e-06 26.4 0.1 3.0 3 0 0 3 3 3 1 PAN domain EGF_3 PF12947.2 EAK88814.1 - 0.0012 18.7 3.3 0.0012 18.7 2.3 7.0 6 1 1 7 7 7 4 EGF domain EGF PF00008.22 EAK88814.1 - 0.0031 17.4 65.8 0.021 14.7 0.5 7.2 6 1 1 7 7 7 5 EGF-like domain EGF_MSP1_1 PF12946.2 EAK88814.1 - 0.0039 16.9 2.0 0.0039 16.9 1.4 6.5 6 0 0 6 6 6 2 MSP1 EGF domain 1 hEGF PF12661.2 EAK88814.1 - 0.35 11.0 27.6 0.23 11.6 0.4 6.3 6 0 0 6 6 6 0 Human growth factor-like EGF zf-LYAR PF08790.6 EAK88816.1 - 2e-14 52.9 6.9 2e-14 52.9 4.8 2.3 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger T4_baseplate PF12322.3 EAK88816.1 - 0.00021 20.6 4.5 0.00028 20.2 3.1 1.2 1 0 0 1 1 1 1 T4 bacteriophage base plate protein Cullin_Nedd8 PF10557.4 EAK88816.1 - 0.026 14.3 0.1 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Cullin protein neddylation domain HORMA PF02301.13 EAK88816.1 - 0.066 12.6 0.1 0.099 12.1 0.1 1.3 1 0 0 1 1 1 0 HORMA domain DUF4065 PF13274.1 EAK88816.1 - 0.068 13.8 0.5 0.097 13.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) Crust_neurohorm PF01147.12 EAK88816.1 - 0.89 8.9 7.4 2 7.8 5.0 1.8 1 1 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Squash PF00299.13 EAK88816.1 - 1.1 9.1 5.1 2.6 7.9 0.7 2.5 2 0 0 2 2 2 0 Squash family serine protease inhibitor NPR2 PF06218.6 EAK88817.1 - 4.3e-36 124.5 11.7 1.9e-35 122.4 5.0 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 CorA PF01544.13 EAK88818.1 - 0.00024 20.2 0.7 0.00024 20.2 0.5 2.1 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein TruD PF01142.13 EAK88819.1 - 5.5e-49 166.8 0.5 4.6e-46 157.1 0.1 3.2 3 0 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) PCI PF01399.22 EAK88820.1 - 5e-11 42.8 2.2 1.1e-10 41.7 0.7 2.2 2 0 0 2 2 2 1 PCI domain eIF3_N PF09440.5 EAK88820.1 - 0.0013 18.9 0.4 0.0032 17.6 0.3 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain RP-C_C PF11800.3 EAK88820.1 - 0.049 13.3 6.4 0.16 11.6 0.2 3.0 3 0 0 3 3 3 0 Replication protein C C-terminal region RRM_1 PF00076.17 EAK88821.1 - 2e-14 52.9 0.0 7.6e-11 41.4 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK88821.1 - 1.4e-07 31.3 0.0 0.00018 21.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK88821.1 - 0.00016 21.4 0.0 0.00095 18.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1084 PF06454.6 EAK88822.1 - 1.6e-12 47.0 20.3 2.3e-12 46.5 14.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Bromo_TP PF07524.8 EAK88823.1 - 0.00048 19.7 0.0 0.00081 19.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 EAK88823.1 - 0.25 11.4 0.9 0.5 10.4 0.6 1.4 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term DUF1754 PF08555.5 EAK88824.1 - 2.1e-16 60.3 0.7 3.1e-16 59.7 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) MFS_1 PF07690.11 EAK88825.1 - 1.6e-21 76.4 31.7 1.6e-21 76.4 22.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAK88825.1 - 1e-09 37.5 13.9 1e-09 37.5 9.7 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EAK88825.1 - 3.7e-09 35.1 26.4 3.2e-05 22.2 4.3 3.2 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 EAK88825.1 - 0.02 14.8 6.0 0.025 14.6 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Dynactin_p62 PF05502.8 EAK88826.1 - 1.3e-27 96.7 23.9 9.7e-25 87.2 16.6 2.2 1 1 0 1 1 1 1 Dynactin p62 family Fzo_mitofusin PF04799.8 EAK88826.1 - 0.036 13.4 2.1 0.066 12.5 1.5 1.4 1 0 0 1 1 1 0 fzo-like conserved region zinc-ribbons_6 PF07191.7 EAK88826.1 - 0.085 12.6 0.4 0.085 12.6 0.3 4.2 3 1 1 4 4 4 0 zinc-ribbons zf-FPG_IleRS PF06827.9 EAK88826.1 - 0.65 9.6 5.9 0.28 10.8 0.3 3.0 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Fer4_10 PF13237.1 EAK88826.1 - 3.3 7.5 17.7 0.31 10.8 1.8 3.2 3 0 0 3 3 3 0 4Fe-4S dicluster domain DnaJ PF00226.26 EAK88827.1 - 1.6e-05 24.4 2.7 2e-05 24.2 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain DUF953 PF06110.6 EAK88827.1 - 0.025 14.0 0.1 0.068 12.6 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) CENP-Q PF13094.1 EAK88828.1 - 0.01 15.8 1.6 0.024 14.6 1.1 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit NGP1NT PF08153.7 EAK88828.1 - 0.081 12.8 3.0 10 6.0 0.3 2.9 2 1 1 3 3 3 0 NGP1NT (NUC091) domain Ndc1_Nup PF09531.5 EAK88829.1 - 2.5 6.4 5.2 2.5 6.4 3.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 EAK88831.1 - 0.001 19.0 4.9 0.086 12.8 2.7 3.1 2 1 0 2 2 2 1 Syntaxin-like protein Laminin_II PF06009.7 EAK88831.1 - 0.004 16.9 7.1 0.23 11.2 2.4 3.5 2 1 1 3 3 3 1 Laminin Domain II DUF948 PF06103.6 EAK88831.1 - 0.0071 16.1 4.0 0.24 11.2 0.4 3.6 2 1 0 3 3 3 1 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 EAK88831.1 - 0.048 13.4 6.5 0.017 14.8 1.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EAK88831.1 - 0.079 13.2 15.2 0.11 12.7 0.9 4.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EAK88831.1 - 0.083 12.4 0.5 0.18 11.3 0.3 1.6 1 0 0 1 1 1 0 IncA protein COG2 PF06148.6 EAK88831.1 - 0.12 12.2 5.3 0.3 10.9 0.9 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2618 PF10940.3 EAK88831.1 - 0.13 12.0 0.6 51 3.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2618) DUF2408 PF10303.4 EAK88831.1 - 0.18 11.8 6.6 6 6.9 2.7 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Rsbr_N PF08678.5 EAK88831.1 - 0.24 11.2 9.9 0.022 14.6 2.3 2.7 2 1 1 3 3 3 0 Rsbr N terminal Cluap1 PF10234.4 EAK88831.1 - 0.39 9.8 6.7 1 8.4 4.6 1.6 1 1 0 1 1 1 0 Clusterin-associated protein-1 FlaC_arch PF05377.6 EAK88831.1 - 5.9 6.8 9.0 1 9.3 0.6 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) PI3_PI4_kinase PF00454.22 EAK88832.1 - 1.2e-30 106.7 0.0 2.5e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MFS_1 PF07690.11 EAK88833.1 - 5e-07 28.7 16.0 5e-07 28.7 11.1 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily FLILHELTA PF10306.4 EAK88833.1 - 0.35 10.9 2.3 0.52 10.3 0.5 2.0 2 0 0 2 2 2 0 Hypothetical protein FLILHELTA Pkinase PF00069.20 EAK88834.1 - 1.8e-75 253.4 0.0 3.2e-75 252.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK88834.1 - 2.9e-32 111.7 0.0 4.6e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EAK88834.1 - 2.9e-27 91.8 6.8 1.3e-06 27.3 0.9 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EAK88834.1 - 4.8e-24 84.2 5.2 4.6e-12 45.8 0.4 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EAK88834.1 - 3.9e-22 76.5 5.0 9.5e-07 27.8 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EAK88834.1 - 2.9e-20 70.2 5.1 0.00014 21.4 0.0 4.9 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EAK88834.1 - 6e-20 70.6 9.3 8.8e-10 38.0 0.9 4.5 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EAK88834.1 - 3.4e-07 30.2 2.6 0.029 14.4 0.1 3.4 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EAK88834.1 - 0.00019 21.2 0.3 0.0081 16.0 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 EAK88834.1 - 0.0006 19.5 2.5 0.26 11.0 0.3 3.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand APH PF01636.18 EAK88834.1 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EAK88834.1 - 0.02 13.5 1.3 1.4 7.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1679) Kdo PF06293.9 EAK88834.1 - 0.11 11.5 0.0 0.28 10.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SseC PF04888.7 EAK88834.1 - 0.11 11.7 0.5 0.19 11.0 0.3 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF2951 PF11166.3 EAK88836.1 - 2.3 8.1 5.3 7.7 6.4 1.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) DDHD PF02862.12 EAK88837.1 - 1.6e-46 158.9 1.6 1.7e-45 155.5 0.0 2.3 2 0 0 2 2 2 1 DDHD domain DUF676 PF05057.9 EAK88837.1 - 2.8e-05 23.5 1.9 0.00029 20.1 1.3 2.2 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DUF2305 PF10230.4 EAK88837.1 - 0.00026 20.5 1.4 0.0003 20.2 0.2 1.6 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 EAK88837.1 - 0.0013 17.7 0.0 0.0026 16.8 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 EAK88837.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EAK88837.1 - 0.0016 18.0 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EAK88837.1 - 0.0025 17.4 0.5 0.019 14.5 0.0 2.6 3 0 0 3 3 3 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EAK88837.1 - 0.0064 16.2 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 EAK88837.1 - 0.032 13.4 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Guanylate_cyc PF00211.15 EAK88839.1 - 2.2e-14 53.2 0.0 5.4e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Afaf PF15339.1 EAK88839.1 - 0.39 10.2 5.8 1.5 8.3 0.4 2.3 2 0 0 2 2 2 0 Acrosome formation-associated factor EST1 PF10374.4 EAK88840.1 - 4.1 7.4 8.5 2.7 8.0 2.3 2.9 2 1 0 2 2 2 0 Telomerase activating protein Est1 PTS_2-RNA PF01885.11 EAK88841.1 - 1.8e-51 174.0 0.0 2.2e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Methyltransf_15 PF09445.5 EAK88842.1 - 2.9e-24 85.4 2.6 9.7e-14 51.2 0.1 2.5 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 EAK88842.1 - 0.00066 19.1 0.0 0.0018 17.7 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 EAK88842.1 - 0.0015 19.1 0.0 0.0053 17.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Steroid_dh PF02544.11 EAK88843.1 - 1.2e-32 112.7 8.2 2.5e-32 111.7 5.7 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 EAK88843.1 - 5e-05 22.6 0.0 8.9e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family MFS_1 PF07690.11 EAK88843.1 - 0.037 12.7 8.3 0.05 12.2 5.8 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily UAE_UbL PF14732.1 EAK88843.1 - 0.09 12.8 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Rad60-SLD PF11976.3 EAK88843.1 - 0.1 12.3 0.0 0.24 11.0 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Paf67 PF10255.4 EAK88844.1 - 4.2e-138 460.5 5.7 4.2e-138 460.5 3.9 1.5 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EAK88844.1 - 0.0032 17.2 0.0 0.0083 15.9 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat KorB PF08535.5 EAK88844.1 - 0.019 15.0 0.0 13 5.9 0.0 3.3 3 0 0 3 3 3 0 KorB domain TPR_12 PF13424.1 EAK88844.1 - 0.059 13.3 0.1 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Pox_E10 PF04805.7 EAK88844.1 - 1.5 8.4 8.4 2.4 7.7 1.3 3.1 3 0 0 3 3 3 0 E10-like protein conserved region SNARE PF05739.14 EAK88845.1 - 1.8e-16 59.5 0.5 6.9e-16 57.6 0.4 2.1 1 0 0 1 1 1 1 SNARE domain CTK3 PF12243.3 EAK88845.1 - 0.0024 17.4 1.7 0.0042 16.7 0.3 2.0 1 1 2 3 3 3 1 CTD kinase subunit gamma CTK3 Gemini_BL1 PF00845.14 EAK88845.1 - 0.011 15.1 1.2 0.014 14.7 0.8 1.3 1 0 0 1 1 1 0 Geminivirus BL1 movement protein DUF3394 PF11874.3 EAK88845.1 - 0.016 14.7 0.4 0.034 13.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Mdv1 PF11542.3 EAK88845.1 - 0.038 13.9 0.6 0.13 12.1 0.4 1.9 1 0 0 1 1 1 0 Mitochondrial division protein 1 Reo_sigmaC PF04582.7 EAK88845.1 - 0.061 12.4 3.7 0.084 12.0 0.1 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF2116 PF09889.4 EAK88845.1 - 0.079 12.7 1.5 0.24 11.2 1.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF357 PF04010.8 EAK88845.1 - 0.22 11.2 1.6 0.34 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF357) Atg14 PF10186.4 EAK88845.1 - 0.42 9.5 20.2 0.08 11.8 9.1 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3899 PF13038.1 EAK88845.1 - 2 8.6 5.4 1.3 9.2 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) Flu_NS2 PF00601.14 EAK88845.1 - 3 8.1 11.1 0.23 11.7 0.3 3.4 2 1 2 4 4 4 0 Influenza non-structural protein (NS2) Synaptobrevin PF00957.16 EAK88845.1 - 8.2 6.1 15.4 3.5 7.3 4.1 2.9 2 2 0 2 2 2 0 Synaptobrevin DUF912 PF06024.7 EAK88845.1 - 10 6.2 9.8 0.16 12.0 0.2 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ThiF PF00899.16 EAK88847.1 - 4e-38 130.3 0.0 8.7e-38 129.2 0.0 1.6 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EAK88847.1 - 6.1e-15 54.5 0.9 1.3e-13 50.3 0.6 2.5 1 1 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EAK88847.1 - 1.2e-06 28.8 0.9 9.7e-06 25.9 0.0 2.7 3 0 0 3 3 3 1 Rhodanese-like domain Shikimate_DH PF01488.15 EAK88847.1 - 0.0026 17.8 0.2 0.0096 16.0 0.1 1.9 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EAK88847.1 - 0.032 13.8 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EAK88847.1 - 0.051 13.0 0.1 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ELFV_dehydrog PF00208.16 EAK88847.1 - 0.068 12.7 0.1 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 EAK88847.1 - 0.12 11.5 0.1 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_S25 PF03297.10 EAK88848.1 - 2.7e-35 120.5 2.6 2.9e-35 120.4 1.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 EAK88848.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Gly_radical PF01228.16 EAK88849.1 - 0.064 13.6 0.4 2.2 8.6 0.0 3.2 3 0 0 3 3 3 0 Glycine radical MCM PF00493.18 EAK88850.1 - 3.8e-136 453.2 0.3 5.8e-136 452.6 0.2 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EAK88850.1 - 5.8e-22 78.3 20.8 5.8e-22 78.3 14.4 2.3 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EAK88850.1 - 1.8e-18 67.2 0.2 1.8e-18 67.2 0.2 3.1 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EAK88850.1 - 4.9e-07 29.1 0.0 3.5e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EAK88850.1 - 0.00019 21.0 0.0 0.00059 19.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAK88850.1 - 0.00019 21.1 0.0 0.00042 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EAK88850.1 - 0.004 16.6 0.0 0.048 13.1 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain MBOAT PF03062.14 EAK88851.1 - 4.8e-19 68.6 40.1 4.1e-18 65.5 27.8 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EAK88851.1 - 0.99 9.5 11.6 0.061 13.4 3.6 2.4 3 0 0 3 3 3 0 Membrane bound O-acyl transferase family Pkinase PF00069.20 EAK88852.1 - 2.8e-75 252.8 0.0 4.6e-75 252.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK88852.1 - 8.1e-36 123.4 0.0 1.5e-35 122.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EAK88852.1 - 1.5e-27 92.7 5.8 2.7e-08 32.5 1.4 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EAK88852.1 - 3.4e-26 91.1 0.5 9.8e-12 44.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EAK88852.1 - 4.1e-20 69.7 3.7 1.9e-05 24.1 0.0 4.9 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EAK88852.1 - 1.5e-18 65.1 6.0 0.00066 18.9 0.5 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EAK88852.1 - 3.2e-15 55.4 4.8 6.3e-05 22.5 0.4 5.1 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_4 PF12763.2 EAK88852.1 - 1.2e-05 24.9 0.5 0.19 11.4 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.1 EAK88852.1 - 5.7e-05 22.2 0.0 8.9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like EF-hand_9 PF14658.1 EAK88852.1 - 0.011 15.6 0.0 0.054 13.4 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain Kdo PF06293.9 EAK88852.1 - 0.014 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Caleosin PF05042.8 EAK88852.1 - 0.024 14.1 0.0 0.076 12.5 0.0 1.9 1 1 0 1 1 1 0 Caleosin related protein APH PF01636.18 EAK88852.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family PCI PF01399.22 EAK88854.1 - 2.1e-08 34.4 0.1 2.1e-08 34.4 0.1 2.9 3 0 0 3 3 3 1 PCI domain RRM_1 PF00076.17 EAK88855.1 - 2.7e-13 49.3 0.0 9e-11 41.2 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK88855.1 - 2.9e-10 39.9 0.0 1.4e-06 28.1 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK88855.1 - 2.4e-09 36.9 0.1 0.00013 21.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1897 PF09005.5 EAK88855.1 - 0.16 11.4 0.6 0.28 10.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) TGT PF01702.13 EAK88856.1 - 1.4e-51 175.1 0.0 2.2e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Tcp10_C PF07202.8 EAK88858.1 - 0.00021 20.8 0.1 0.00083 18.9 0.0 2.1 1 1 0 1 1 1 1 T-complex protein 10 C-terminus ERM PF00769.14 EAK88858.1 - 0.00043 19.9 27.4 0.00043 19.9 19.0 1.7 2 0 0 2 2 2 1 Ezrin/radixin/moesin family PPTA PF01239.17 EAK88859.1 - 0.00088 18.5 3.0 2.4 7.6 0.4 4.8 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat Peptidase_M16 PF00675.15 EAK88861.1 - 7.7e-33 113.3 0.0 1.5e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAK88861.1 - 1.4e-27 96.5 0.2 5.7e-18 65.2 0.0 3.1 2 0 0 2 2 2 2 Peptidase M16 inactive domain DUF1014 PF06244.7 EAK88863.1 - 9.8e-24 83.8 31.9 1.2e-21 77.1 22.1 2.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 EAK88863.1 - 1.6e-05 25.0 0.7 1.6e-05 25.0 0.5 3.3 2 1 0 2 2 2 1 HMG (high mobility group) box DUF1002 PF06207.6 EAK88863.1 - 8.9e-05 21.9 2.4 8.9e-05 21.9 1.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1002) YABBY PF04690.8 EAK88863.1 - 3.9 7.6 12.9 0.099 12.8 0.3 2.2 1 1 1 2 2 2 0 YABBY protein DUF846 PF05832.7 EAK88865.1 - 3.2e-44 150.0 20.6 4.1e-44 149.7 14.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) HXXEE PF13787.1 EAK88865.1 - 0.33 11.3 10.0 0.06 13.7 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif PC4 PF02229.11 EAK88865.1 - 0.56 9.4 3.0 0.24 10.6 0.2 1.7 2 0 0 2 2 2 0 Transcriptional Coactivator p15 (PC4) SUI1 PF01253.17 EAK88866.1 - 9e-28 95.9 0.0 1.1e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 MFS_1 PF07690.11 EAK88867.1 - 3.9e-15 55.4 37.3 1.1e-13 50.6 21.9 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Fels1 PF05666.6 EAK88867.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like LCCL PF03815.14 EAK88868.1 - 3.6e-96 315.3 19.7 6.3e-26 90.2 0.3 4.9 5 0 0 5 5 5 4 LCCL domain SRCR PF00530.13 EAK88868.1 - 4.7e-31 107.0 14.4 6.6e-17 61.6 5.1 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Laminin_G_3 PF13385.1 EAK88868.1 - 2.8e-19 69.9 0.6 9.5e-19 68.1 0.4 2.0 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PLAT PF01477.18 EAK88868.1 - 6.5e-18 65.1 0.1 9.8e-14 51.6 0.0 3.0 2 0 0 2 2 2 2 PLAT/LH2 domain Rxt3 PF08642.5 EAK88868.1 - 8.9e-07 29.1 0.6 0.57 10.4 0.1 5.8 4 3 1 5 5 5 1 Histone deacetylation protein Rxt3 SRCR_2 PF15494.1 EAK88868.1 - 3.3e-05 24.0 6.6 0.00017 21.7 1.3 2.9 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Pentaxin PF00354.12 EAK88868.1 - 5.8e-05 22.6 0.1 0.00012 21.5 0.1 1.4 1 0 0 1 1 1 1 Pentaxin family Sialidase PF02973.11 EAK88868.1 - 0.00028 19.9 0.3 0.00069 18.6 0.2 1.6 1 0 0 1 1 1 1 Sialidase, N-terminal domain YecR PF13992.1 EAK88868.1 - 0.002 18.2 2.4 0.24 11.5 0.6 2.8 2 0 0 2 2 2 1 YecR-like lipoprotein Laminin_G_2 PF02210.19 EAK88868.1 - 0.068 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain Bac_surface_Ag PF01103.18 EAK88870.1 - 6.6e-12 45.5 8.4 1.4e-11 44.4 5.8 1.5 1 1 0 1 1 1 1 Surface antigen CPSF73-100_C PF11718.3 EAK88870.1 - 0.02 14.2 0.4 0.031 13.6 0.3 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Tau95 PF09734.4 EAK88871.1 - 7.7e-62 209.3 0.0 1e-61 208.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit WD40 PF00400.27 EAK88872.1 - 1.4e-17 62.8 1.6 1.9e-05 24.3 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat TYW3 PF02676.9 EAK88872.1 - 0.023 13.8 0.1 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase TYW3 Vps5 PF09325.5 EAK88873.1 - 0.0081 15.4 3.9 0.013 14.7 2.7 1.3 1 0 0 1 1 1 1 Vps5 C terminal like Peptidase_C97 PF05903.9 EAK88874.1 - 2.1e-34 118.4 0.0 3.9e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain zf-RING_2 PF13639.1 EAK88877.1 - 0.067 13.0 4.6 1.3 8.8 0.9 2.8 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 EAK88877.1 - 0.58 9.9 13.0 0.017 14.8 2.3 2.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAK88877.1 - 0.84 9.7 16.0 0.57 10.2 4.1 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAK88877.1 - 1.1 8.9 12.3 1.2 8.8 3.5 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAK88877.1 - 1.2 9.0 9.2 4.2 7.3 2.9 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EAK88877.1 - 5.2 6.8 10.8 0.64 9.7 1.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TBPIP PF07106.8 EAK88878.1 - 1.7e-33 115.5 8.5 1.7e-33 115.5 5.9 2.7 2 1 1 3 3 3 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TFIIE_beta PF02186.10 EAK88878.1 - 0.014 15.4 0.6 0.33 10.9 0.0 2.5 2 0 0 2 2 2 0 TFIIE beta subunit core domain Sad1_UNC PF07738.8 EAK88879.1 - 4.3e-14 52.4 1.6 1.1e-13 51.1 0.5 2.2 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Dfp1_Him1_M PF08630.5 EAK88879.1 - 0.44 10.3 6.1 0.46 10.2 0.1 3.3 3 1 0 3 3 3 0 Dfp1/Him1, central region DUF885 PF05960.6 EAK88879.1 - 0.76 8.8 4.6 0.8 8.7 2.4 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Metallophos PF00149.23 EAK88880.1 - 0.00041 19.7 0.4 0.00065 19.1 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAK88880.1 - 0.026 14.3 0.2 0.17 11.7 0.2 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Cpn60_TCP1 PF00118.19 EAK88881.1 - 3.1e-138 461.4 3.2 4e-138 461.0 2.2 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family IRK PF01007.15 EAK88883.1 - 1.4e-13 50.3 11.9 2.4e-06 26.6 7.3 2.4 2 1 0 2 2 2 2 Inward rectifier potassium channel Ion_trans_2 PF07885.11 EAK88883.1 - 0.21 11.3 12.2 0.59 9.8 8.4 1.8 1 1 0 1 1 1 0 Ion channel TRAPPC10 PF12584.3 EAK88884.1 - 6e-05 22.5 0.2 0.00024 20.6 0.1 2.1 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Glutenin_hmw PF03157.8 EAK88884.1 - 1.5 6.9 0.1 2.2 6.4 0.1 1.1 1 0 0 1 1 1 0 High molecular weight glutenin subunit Solute_trans_a PF03619.11 EAK88886.1 - 0.00047 19.5 14.9 0.00047 19.5 10.3 1.4 1 1 0 1 1 1 1 Organic solute transporter Ostalpha DUF2976 PF11190.3 EAK88886.1 - 0.36 10.3 8.7 0.18 11.3 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) BRCT PF00533.21 EAK88887.1 - 0.00028 20.9 8.6 0.011 15.8 0.0 4.0 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain VIT PF08487.5 EAK88887.1 - 0.05 13.3 0.3 0.05 13.3 0.2 1.9 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain DUF1241 PF06840.6 EAK88888.1 - 0.0004 19.6 0.7 0.0072 15.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) Peptidase_S49_N PF08496.5 EAK88888.1 - 1.2 8.8 7.0 6.9 6.4 0.1 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Nucleoplasmin PF03066.10 EAK88888.1 - 2.9 7.4 11.9 1.1 8.8 0.6 2.3 2 0 0 2 2 2 0 Nucleoplasmin Porin_3 PF01459.17 EAK88890.1 - 0.0049 16.2 2.6 0.0049 16.2 1.8 2.6 3 1 0 3 3 3 1 Eukaryotic porin F_actin_bind PF08919.5 EAK88890.1 - 0.052 13.2 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 F-actin binding Ribosomal_S6e PF01092.14 EAK88891.1 - 1.6e-54 182.9 0.1 2.9e-54 182.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e bZIP_Maf PF03131.12 EAK88891.1 - 1.4 9.3 11.0 2.2 8.6 7.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Peptidase_M16 PF00675.15 EAK88892.1 - 2.2e-22 79.3 0.5 7.6e-21 74.4 0.0 3.0 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAK88892.1 - 2.2e-16 60.0 0.7 1.2e-09 38.1 0.1 3.6 3 0 0 3 3 3 3 Peptidase M16 inactive domain GAD PF02938.9 EAK88892.1 - 0.00097 19.2 0.0 1.3 9.2 0.0 2.9 2 0 0 2 2 2 2 GAD domain Pyr_redox_2 PF07992.9 EAK88893.1 - 1e-34 120.2 0.1 1.4e-34 119.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EAK88893.1 - 6e-22 77.7 0.0 1.7e-21 76.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EAK88893.1 - 1e-16 61.0 1.8 5.1e-12 46.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAK88893.1 - 4.7e-09 36.6 0.0 1.3e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAK88893.1 - 1.5e-08 33.5 0.7 0.00014 20.4 1.0 2.3 1 1 1 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EAK88893.1 - 3.8e-08 32.6 1.5 1.5e-06 27.3 0.5 2.5 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 EAK88893.1 - 4.4e-06 25.8 3.0 0.0031 16.4 0.3 3.7 3 1 0 4 4 4 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EAK88893.1 - 7.1e-06 25.3 0.1 1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EAK88893.1 - 7.2e-06 25.1 0.0 1.6e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EAK88893.1 - 4.7e-05 22.5 0.2 1.3 7.9 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EAK88893.1 - 6e-05 22.9 2.1 0.00037 20.4 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EAK88893.1 - 0.00061 18.9 1.8 0.00082 18.5 0.3 1.9 2 1 1 3 3 3 1 Thi4 family K_oxygenase PF13434.1 EAK88893.1 - 0.007 15.3 0.0 0.015 14.2 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EAK88893.1 - 0.042 13.4 0.1 3.8 7.0 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HrpB7 PF09486.5 EAK88894.1 - 0.0017 18.2 3.2 0.0019 18.1 0.4 2.2 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB7) TPR_MLP1_2 PF07926.7 EAK88894.1 - 0.0031 17.2 14.9 0.0031 17.2 10.3 2.7 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 EAK88894.1 - 0.14 11.7 24.7 0.071 12.7 6.2 2.6 2 0 0 2 2 2 0 IncA protein DUF4200 PF13863.1 EAK88894.1 - 0.37 10.7 26.7 0.47 10.4 9.6 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.17 EAK88894.1 - 0.38 10.7 32.5 0.2 11.7 6.2 4.1 3 2 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain FliJ PF02050.11 EAK88894.1 - 0.56 10.2 19.6 0.34 10.9 6.1 2.8 2 1 0 2 2 2 0 Flagellar FliJ protein UPF0449 PF15136.1 EAK88894.1 - 0.71 10.1 10.8 0.071 13.3 1.7 2.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF641 PF04859.7 EAK88894.1 - 3.7 7.3 18.0 0.43 10.3 4.4 3.2 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Enkurin PF13864.1 EAK88894.1 - 4.7 7.4 32.1 0.75 10.0 5.4 3.9 3 1 1 4 4 4 0 Calmodulin-binding MbeD_MobD PF04899.7 EAK88894.1 - 5.5 6.9 12.1 13 5.7 0.3 3.3 2 1 1 3 3 3 0 MbeD/MobD like Tim17 PF02466.14 EAK88895.1 - 1.5e-24 86.4 5.0 2e-24 86.0 3.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PUCC PF03209.10 EAK88895.1 - 0.051 12.2 0.5 0.074 11.7 0.2 1.5 1 1 0 1 1 1 0 PUCC protein MMR_HSR1 PF01926.18 EAK88896.1 - 9e-16 57.8 0.1 1.7e-13 50.5 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAK88896.1 - 2.5e-05 23.5 0.0 0.00041 19.6 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EAK88896.1 - 0.035 13.3 0.0 0.078 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 EAK88896.1 - 0.14 12.6 2.1 0.36 11.3 0.0 2.8 3 0 0 3 3 3 0 Miro-like protein Pkinase PF00069.20 EAK88897.1 - 2e-42 145.1 6.0 5.5e-38 130.6 0.8 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAK88897.1 - 9.4e-28 96.9 1.0 4.3e-24 84.9 0.7 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAK88897.1 - 9.8e-05 21.4 0.1 0.00029 19.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EAK88897.1 - 0.0098 14.9 0.1 0.019 14.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAK88897.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EAK88897.1 - 0.16 11.3 6.1 0.16 11.2 0.2 2.5 2 0 0 2 2 2 0 RIO1 family WD40 PF00400.27 EAK88898.1 - 0.0099 15.7 0.1 0.0099 15.7 0.1 3.3 4 0 0 4 4 4 1 WD domain, G-beta repeat zf-CHY PF05495.7 EAK88899.1 - 1.8e-14 53.6 17.0 1.8e-14 53.6 11.8 3.8 2 1 1 3 3 3 1 CHY zinc finger Myb_DNA-bind_6 PF13921.1 EAK88899.1 - 2.1e-05 24.5 0.5 0.00018 21.5 0.2 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAK88899.1 - 2.2e-05 24.3 0.2 5.3e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3133 PF11331.3 EAK88899.1 - 2.4 7.7 8.6 20 4.8 2.1 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3133) UCH PF00443.24 EAK88900.1 - 6.8e-45 153.2 2.9 9e-45 152.8 2.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAK88900.1 - 9.1e-12 45.0 10.1 8.2e-11 41.8 7.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HNH_5 PF14279.1 EAK88900.1 - 0.019 14.9 0.1 0.07 13.1 0.1 2.0 1 0 0 1 1 1 0 HNH endonuclease DUF2073 PF09846.4 EAK88900.1 - 0.15 11.7 0.0 1 9.0 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) zf-HIT PF04438.11 EAK88900.1 - 0.15 11.7 4.4 2.7 7.7 0.5 2.4 2 0 0 2 2 2 0 HIT zinc finger PCI_Csn8 PF10075.4 EAK88901.1 - 4.9e-22 78.2 0.8 8.2e-22 77.5 0.6 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EAK88901.1 - 7.6e-21 74.5 5.1 1.3e-20 73.8 3.5 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF2075 PF09848.4 EAK88901.1 - 0.078 11.9 0.1 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Peptidase_C1 PF00112.18 EAK88902.1 - 1e-30 107.2 17.6 6.7e-21 75.1 1.1 3.1 2 1 0 2 2 2 2 Papain family cysteine protease CathepsinC_exc PF08773.6 EAK88902.1 - 3.6e-10 40.0 3.8 1.9e-06 28.0 1.2 2.8 2 0 0 2 2 2 2 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.10 EAK88902.1 - 0.00017 20.2 0.6 0.00038 19.1 0.4 1.4 1 0 0 1 1 1 1 Peptidase C1-like family OmpH PF03938.9 EAK88902.1 - 0.0079 16.1 6.1 0.016 15.1 4.2 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Zip PF02535.17 EAK88902.1 - 0.011 14.7 3.8 0.016 14.2 2.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 EAK88902.1 - 0.06 11.3 16.7 0.084 10.8 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EAK88902.1 - 0.3 8.9 22.2 0.57 8.0 15.4 1.4 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.6 EAK88902.1 - 0.7 9.7 11.4 1.2 8.8 7.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ArfGap PF01412.13 EAK88903.1 - 3.5e-33 113.8 0.1 1.2e-32 112.0 0.1 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Tmemb_cc2 PF10267.4 EAK88903.1 - 0.063 11.8 6.7 0.018 13.6 2.8 1.4 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Methyltransf_29 PF03141.11 EAK88903.1 - 0.085 11.1 0.0 0.15 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Tape_meas_lam_C PF09718.5 EAK88903.1 - 1.3 9.0 5.0 3.6 7.5 0.1 2.8 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Ribosomal_S28e PF01200.13 EAK88904.1 - 3.2e-31 106.8 1.4 3.4e-31 106.7 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e PH PF00169.24 EAK88905.1 - 3.8e-06 27.0 0.7 3.1e-05 24.1 0.5 2.6 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.2 EAK88905.1 - 4e-06 27.0 0.0 1.3e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EAK88905.1 - 0.00017 21.2 0.1 0.85 9.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Reo_sigmaC PF04582.7 EAK88905.1 - 0.0037 16.5 1.3 0.0037 16.5 0.9 2.4 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Ank_5 PF13857.1 EAK88905.1 - 0.0078 16.4 0.0 0.026 14.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAK88905.1 - 0.0093 16.4 0.3 3.4 8.2 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) PH_11 PF15413.1 EAK88905.1 - 0.014 15.6 0.1 0.11 12.7 0.0 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain Ank_3 PF13606.1 EAK88905.1 - 0.11 12.7 0.4 1.2 9.5 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat IncA PF04156.9 EAK88905.1 - 1.1 8.8 34.2 0.36 10.4 10.0 4.1 1 1 2 3 3 3 0 IncA protein DUF1664 PF07889.7 EAK88905.1 - 1.9 8.3 12.8 0.32 10.7 3.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 EAK88905.1 - 2.3 7.9 30.5 0.12 12.2 9.3 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Methyltransf_31 PF13847.1 EAK88906.1 - 4.5e-19 68.5 0.0 7.5e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EAK88906.1 - 2.1e-10 39.8 1.6 1.5e-09 37.0 1.0 2.4 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.9 EAK88906.1 - 4.6e-07 29.3 0.0 9.1e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EAK88906.1 - 7.9e-07 29.6 0.0 1.5e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAK88906.1 - 6.9e-06 26.3 0.0 1.8e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAK88906.1 - 1.7e-05 24.8 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EAK88906.1 - 2.7e-05 23.8 0.0 5.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAK88906.1 - 3.3e-05 23.1 0.0 7.4e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EAK88906.1 - 6.2e-05 22.1 0.1 0.00015 20.8 0.1 1.7 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EAK88906.1 - 0.00099 19.5 0.0 0.0023 18.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EAK88906.1 - 0.018 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 EAK88906.1 - 0.14 12.6 0.0 0.48 10.9 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Glutaredoxin PF00462.19 EAK88907.1 - 1.6e-13 50.4 0.1 2.4e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EAK88907.1 - 0.02 15.0 0.0 0.026 14.7 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SPOC PF07744.8 EAK88907.1 - 0.081 13.4 0.0 0.089 13.2 0.0 1.2 1 0 0 1 1 1 0 SPOC domain DNA_pol_E_B PF04042.11 EAK88908.1 - 2.3e-19 69.5 1.7 1.2e-18 67.0 1.2 2.1 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF2691 PF10903.3 EAK88908.1 - 0.03 14.1 3.1 0.09 12.5 2.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2691) UPF0029 PF01205.14 EAK88909.1 - 2.2e-29 101.3 0.0 3.2e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Ribosomal_L37e PF01907.14 EAK88910.1 - 3.1e-25 87.7 14.4 5.6e-25 86.8 10.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EAK88910.1 - 0.014 15.2 1.2 0.023 14.5 0.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon SelR PF01641.13 EAK88910.1 - 0.018 14.7 0.3 0.02 14.6 0.2 1.3 1 1 0 1 1 1 0 SelR domain HypA PF01155.14 EAK88910.1 - 0.073 12.7 1.1 0.11 12.2 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 EAK88910.1 - 0.082 12.4 0.8 0.14 11.6 0.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-P11 PF03854.9 EAK88910.1 - 0.12 11.8 0.7 0.18 11.3 0.5 1.2 1 0 0 1 1 1 0 P-11 zinc finger zf-ribbon_3 PF13248.1 EAK88910.1 - 0.16 11.2 1.4 0.42 9.8 1.0 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 EAK88910.1 - 0.16 11.6 2.0 0.23 11.1 1.4 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK88910.1 - 0.61 10.1 4.5 0.95 9.5 3.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-DHHC PF01529.15 EAK88911.1 - 4.9e-37 126.9 14.6 4.9e-37 126.9 10.1 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase CTV_P6 PF06706.6 EAK88911.1 - 0.023 14.1 0.7 0.023 14.1 0.5 2.6 2 1 0 2 2 2 0 Citrus tristeza virus 6-kDa protein HMG_box PF00505.14 EAK88912.1 - 2.4e-21 75.7 2.0 2.4e-21 75.7 1.4 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAK88912.1 - 7.3e-18 64.7 5.5 1.2e-17 64.0 3.8 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EAK88912.1 - 5.5e-05 22.8 1.3 5.5e-05 22.8 0.9 1.8 1 1 1 2 2 2 1 HMG (high mobility group) box 5 Imm35 PF15581.1 EAK88912.1 - 0.0023 17.9 0.8 0.0035 17.3 0.0 1.7 1 1 1 2 2 2 1 Immunity protein 35 RIB43A PF05914.7 EAK88912.1 - 0.0096 14.5 4.3 0.013 14.1 3.0 1.2 1 0 0 1 1 1 1 RIB43A Clp1 PF06807.9 EAK88912.1 - 0.12 12.1 0.2 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 Proteasome PF00227.21 EAK88913.1 - 3.2e-56 189.6 0.0 4.3e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAK88913.1 - 9.7e-13 47.1 0.0 1.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ArfGap PF01412.13 EAK88914.1 - 8.8e-40 135.1 0.7 8.8e-40 135.1 0.5 2.2 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf DUF4259 PF14078.1 EAK88914.1 - 0.25 11.8 1.7 0.5 10.8 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) EF-hand_1 PF00036.27 EAK88915.1 - 8.1e-14 49.8 0.6 1.5e-05 23.9 0.0 2.9 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 EAK88915.1 - 1.9e-12 47.0 0.2 3.1e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EAK88915.1 - 4.1e-12 44.8 0.2 9.2e-05 22.0 0.4 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EAK88915.1 - 3.8e-10 38.6 0.8 0.001 18.3 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EAK88915.1 - 1.4e-08 34.2 2.9 0.006 16.1 0.2 4.5 3 2 2 5 5 5 3 EF-hand domain pair Caleosin PF05042.8 EAK88915.1 - 0.0016 18.0 0.0 0.07 12.6 0.0 2.1 2 0 0 2 2 2 1 Caleosin related protein Toprim PF01751.17 EAK88915.1 - 0.075 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Toprim domain EF-hand_9 PF14658.1 EAK88915.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain Dockerin_1 PF00404.13 EAK88915.1 - 0.39 10.5 3.3 3.8 7.3 0.0 2.8 3 0 0 3 3 3 0 Dockerin type I repeat DUF751 PF05421.6 EAK88916.1 - 0.1 12.8 4.5 2.6 8.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF751) ORC4_C PF14629.1 EAK88917.1 - 3.4e-22 78.8 3.1 5.8e-22 78.0 2.2 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EAK88917.1 - 0.0016 18.4 0.0 0.0047 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAK88917.1 - 0.0081 16.3 0.5 0.035 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Proteasome PF00227.21 EAK88918.1 - 1.6e-55 187.3 0.0 2.4e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAK88918.1 - 8.8e-15 53.7 0.0 1.4e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1669 PF07894.7 EAK88918.1 - 0.011 14.9 0.5 0.016 14.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) AAA PF00004.24 EAK88919.1 - 4.9e-42 143.2 0.0 1.3e-41 141.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAK88919.1 - 2.8e-06 27.1 1.3 4.9e-05 23.0 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EAK88919.1 - 3.9e-05 22.8 0.0 0.00017 20.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EAK88919.1 - 9.1e-05 22.5 0.2 0.0027 17.7 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAK88919.1 - 0.00026 21.1 0.4 0.016 15.3 0.3 2.6 1 1 0 1 1 1 1 AAA domain TMF_TATA_bd PF12325.3 EAK88919.1 - 0.00039 20.1 1.7 0.00039 20.1 1.2 1.8 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding AAA_2 PF07724.9 EAK88919.1 - 0.00073 19.4 0.0 0.0037 17.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF1192 PF06698.6 EAK88919.1 - 0.0012 18.5 0.4 0.003 17.3 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Striatin PF08232.7 EAK88919.1 - 0.0014 18.9 2.1 0.0024 18.1 1.5 1.5 1 0 0 1 1 1 1 Striatin family Mg_chelatase PF01078.16 EAK88919.1 - 0.002 17.3 0.2 0.012 14.8 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EAK88919.1 - 0.003 17.4 0.0 0.0079 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EAK88919.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EAK88919.1 - 0.0059 16.3 0.3 0.016 14.9 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 EAK88919.1 - 0.0073 15.2 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.11 EAK88919.1 - 0.0075 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein Zeta_toxin PF06414.7 EAK88919.1 - 0.02 14.0 0.4 0.066 12.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 EAK88919.1 - 0.025 15.4 0.0 0.082 13.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF1640 PF07798.6 EAK88919.1 - 0.026 14.5 0.3 0.056 13.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) AAA_24 PF13479.1 EAK88919.1 - 0.03 13.9 0.2 0.076 12.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain Spc24 PF08286.6 EAK88919.1 - 0.053 13.2 1.7 0.12 12.0 1.2 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 AAA_14 PF13173.1 EAK88919.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EAK88919.1 - 0.064 12.7 0.0 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 EAK88919.1 - 0.069 12.2 0.4 0.19 10.8 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA_11 PF13086.1 EAK88919.1 - 0.088 12.3 0.1 0.77 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EAK88919.1 - 0.094 12.1 2.4 0.33 10.3 0.1 2.6 2 1 1 3 3 3 0 AAA domain DUF904 PF06005.7 EAK88919.1 - 0.65 10.3 6.3 0.75 10.1 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) MCM PF00493.18 EAK88920.1 - 5.1e-130 433.1 0.2 2.3e-117 391.5 0.1 2.3 2 0 0 2 2 2 2 MCM2/3/5 family MCM_N PF14551.1 EAK88920.1 - 3e-16 59.9 0.0 1.1e-15 58.2 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EAK88920.1 - 3.8e-06 26.2 0.0 0.00013 21.2 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EAK88920.1 - 2.8e-05 23.8 0.0 0.0001 22.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EAK88920.1 - 0.0018 18.6 0.3 0.014 15.7 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EAK88920.1 - 0.0066 16.0 0.0 0.021 14.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) EF-hand_4 PF12763.2 EAK88921.1 - 2.9e-12 46.2 2.2 4e-06 26.5 0.3 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EAK88921.1 - 1.5e-07 30.1 4.6 0.018 14.2 0.3 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EAK88921.1 - 3.8e-07 30.1 1.5 0.0018 18.3 0.8 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EAK88921.1 - 0.00034 20.1 2.5 0.44 10.1 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EAK88921.1 - 0.0016 18.1 5.5 2 8.4 0.2 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EAK88921.1 - 0.0092 15.2 0.9 0.16 11.3 0.0 2.7 2 0 0 2 2 2 1 EF hand DUF2087 PF09860.4 EAK88921.1 - 0.047 13.4 0.2 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) BRE1 PF08647.6 EAK88921.1 - 0.09 12.7 8.6 0.24 11.4 6.0 1.7 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase IncA PF04156.9 EAK88921.1 - 3.9 7.0 7.4 7.2 6.1 5.1 1.4 1 0 0 1 1 1 0 IncA protein RNA_pol_Rpb5_C PF01191.14 EAK88922.1 - 1.1e-35 120.9 0.5 1.9e-35 120.2 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EAK88922.1 - 2.7e-24 85.3 3.5 4.3e-24 84.7 2.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EAK88922.1 - 0.035 13.9 0.3 0.089 12.6 0.2 1.8 1 1 0 1 1 1 0 Restriction endonuclease Peptidase_M16 PF00675.15 EAK88923.1 - 2.2e-33 115.1 1.5 1.1e-32 112.8 0.2 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAK88923.1 - 1e-15 57.9 0.1 4.8e-13 49.2 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Cpn60_TCP1 PF00118.19 EAK88924.1 - 2.7e-130 435.2 6.0 3.1e-130 435.0 4.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Proteasome PF00227.21 EAK88925.1 - 8.2e-48 162.2 0.5 1.2e-47 161.7 0.4 1.2 1 0 0 1 1 1 1 Proteasome subunit Toxin_55 PF15606.1 EAK88925.1 - 0.078 12.9 0.3 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Putative toxin 55 PIG-P PF08510.7 EAK88926.1 - 1.7e-32 111.7 1.3 1.8e-31 108.4 0.9 2.0 1 1 0 1 1 1 1 PIG-P SNAP PF14938.1 EAK88927.1 - 2.3e-61 207.4 16.0 1.9e-58 197.8 11.1 2.8 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EAK88927.1 - 2.2e-07 30.6 3.4 0.0002 21.2 0.1 4.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAK88927.1 - 9.7e-05 21.9 12.7 0.00013 21.5 0.4 4.1 3 1 1 4 4 4 2 TPR repeat Sel1 PF08238.7 EAK88927.1 - 0.00024 21.6 2.0 20 6.0 0.0 5.2 5 0 0 5 5 5 0 Sel1 repeat MIT PF04212.13 EAK88927.1 - 0.0005 19.8 3.9 0.63 9.9 0.0 4.4 4 1 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 EAK88927.1 - 0.00052 19.7 16.3 0.36 10.8 0.1 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAK88927.1 - 0.12 13.0 0.2 17 6.2 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAK88927.1 - 0.23 11.1 17.2 0.23 11.1 0.1 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAK88927.1 - 0.42 10.5 7.6 75 3.4 0.0 5.3 4 1 2 6 6 6 0 Tetratricopeptide repeat NSF PF02071.15 EAK88927.1 - 2.8 8.9 10.0 65 4.8 0.2 6.2 7 0 0 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat MutL_C PF08676.6 EAK88928.1 - 1.9e-16 59.9 3.3 5.1e-16 58.5 0.2 2.8 3 0 0 3 3 3 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EAK88928.1 - 7.8e-16 57.6 1.3 1.2e-15 57.0 0.1 2.0 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EAK88928.1 - 1.4e-10 40.9 2.2 1.4e-10 40.9 1.5 3.1 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EAK88928.1 - 1.5e-09 37.5 0.6 5.5e-09 35.7 0.4 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sec61_beta PF03911.11 EAK88929.1 - 1.4e-16 59.9 0.2 1.7e-16 59.7 0.2 1.1 1 0 0 1 1 1 1 Sec61beta family Nuc_sug_transp PF04142.10 EAK88930.1 - 1.5e-81 273.1 12.9 1.5e-81 273.1 9.0 1.8 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 EAK88930.1 - 3.4e-10 40.1 3.8 3.4e-10 40.1 2.7 3.0 3 1 1 4 4 4 1 Multidrug resistance efflux transporter UAA PF08449.6 EAK88930.1 - 1.1e-06 27.7 11.5 1.1e-06 27.7 7.9 2.5 1 1 0 2 2 2 1 UAA transporter family TPT PF03151.11 EAK88930.1 - 0.00012 21.7 13.1 0.00012 21.7 9.1 3.5 2 2 1 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EAK88930.1 - 0.00064 19.7 10.5 0.00064 19.7 7.3 3.2 2 2 0 2 2 2 1 EamA-like transporter family Ycf66_N PF07444.6 EAK88930.1 - 0.043 13.5 2.2 0.29 10.8 0.5 2.9 2 0 0 2 2 2 0 Ycf66 protein N-terminus UPF0546 PF10639.4 EAK88930.1 - 3.1 7.6 16.3 0.7 9.7 0.5 3.3 2 1 1 3 3 3 0 Uncharacterised protein family UPF0546 PQ-loop PF04193.9 EAK88931.1 - 2e-22 78.4 21.3 4.1e-12 45.4 6.1 2.8 2 1 0 2 2 2 2 PQ loop repeat Nucleos_tra2_N PF01773.15 EAK88931.1 - 0.08 13.3 0.6 0.08 13.3 0.4 3.0 4 0 0 4 4 4 0 Na+ dependent nucleoside transporter N-terminus MtN3_slv PF03083.11 EAK88931.1 - 0.45 10.4 13.0 3.1 7.7 1.3 2.6 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Proteasome PF00227.21 EAK88932.1 - 1.8e-39 134.9 0.0 2.1e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Mito_carr PF00153.22 EAK88933.1 - 5.9e-35 118.8 1.7 7.4e-17 60.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EAK88934.1 - 1.4e-25 88.7 0.1 8.8e-19 66.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK88934.1 - 2e-25 88.5 0.1 3.2e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK88934.1 - 1e-15 57.3 0.7 2.6e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAK88934.1 - 7.7e-06 25.5 0.1 0.17 11.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EAK88934.1 - 0.00075 19.1 0.0 0.73 9.6 0.0 2.7 1 1 1 2 2 2 2 Nup53/35/40-type RNA recognition motif NID PF07292.8 EAK88934.1 - 0.02 14.9 0.0 0.64 10.0 0.0 2.2 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) Cnd1 PF12717.2 EAK88935.1 - 8.5e-06 25.7 2.2 2.1e-05 24.4 0.4 2.0 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EAK88935.1 - 0.0034 17.1 0.2 2 8.3 0.0 3.1 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat PAZ_siRNAbind PF12212.3 EAK88935.1 - 0.034 13.7 0.3 0.07 12.7 0.2 1.5 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain CTDII PF01556.13 EAK88936.1 - 2e-22 78.8 4.1 4.9e-13 48.7 0.1 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 EAK88936.1 - 5.8e-22 77.1 1.6 5.8e-22 77.1 1.1 1.7 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EAK88936.1 - 3.6e-10 39.7 6.5 9.4e-10 38.4 4.5 1.8 1 0 0 1 1 1 1 DnaJ central domain DUF4248 PF14053.1 EAK88936.1 - 0.0068 15.9 0.1 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4248) DASH_Dad1 PF08649.5 EAK88936.1 - 0.022 14.4 0.5 0.061 13.0 0.3 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad1 HypA PF01155.14 EAK88936.1 - 0.18 11.4 3.2 0.1 12.2 0.5 1.8 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-CCHC PF00098.18 EAK88936.1 - 1 9.4 5.8 4.8 7.3 0.1 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-ZPR1 PF03367.8 EAK88937.1 - 4.5e-92 305.4 4.1 2.8e-50 169.6 0.4 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 EAK88937.1 - 0.1 12.3 3.2 0.68 9.6 0.1 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-Mss51 PF13824.1 EAK88937.1 - 0.42 10.5 5.2 6.3 6.7 0.1 3.0 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.1 EAK88937.1 - 0.57 9.4 16.0 1.3 8.3 4.3 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EAK88937.1 - 2 8.2 10.9 9.5 6.1 0.2 3.6 3 1 1 4 4 4 0 Transposase zinc-ribbon domain CpXC PF14353.1 EAK88937.1 - 3.2 7.7 8.2 4.5 7.2 0.1 3.4 3 1 0 3 3 3 0 CpXC protein zf-ISL3 PF14690.1 EAK88937.1 - 4.3 7.4 5.7 16 5.5 0.0 3.0 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 RecR PF02132.10 EAK88937.1 - 5 6.6 7.4 0.3 10.5 1.0 2.1 2 0 0 2 2 2 0 RecR protein Eco57I PF07669.6 EAK88938.1 - 0.088 13.1 1.3 2.2 8.6 0.0 2.8 3 0 0 3 3 3 0 Eco57I restriction-modification methylase Aa_trans PF01490.13 EAK88939.1 - 1.4e-42 145.6 32.7 2e-42 145.1 22.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EAK88939.1 - 4.3e-05 22.5 15.9 4.3e-05 22.5 11.0 2.7 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family MSV199 PF10553.4 EAK88939.1 - 0.083 12.7 4.0 4.6 7.1 0.1 2.7 2 0 0 2 2 2 0 MSV199 domain BRI3BP PF14965.1 EAK88939.1 - 0.098 12.0 2.8 0.15 11.4 0.1 2.5 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Tweety PF04906.8 EAK88941.1 - 0.0056 15.1 2.5 0.0059 15.0 1.0 1.6 1 1 0 1 1 1 1 Tweety V-SNARE_C PF12352.3 EAK88941.1 - 0.011 15.8 0.8 0.037 14.0 0.4 2.0 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.14 EAK88941.1 - 0.025 14.2 0.9 0.069 12.8 0.6 1.7 1 0 0 1 1 1 0 SNARE domain Syntaxin-6_N PF09177.6 EAK88941.1 - 0.048 14.0 5.9 0.37 11.2 0.2 2.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF2524 PF10732.4 EAK88941.1 - 0.09 12.9 1.4 5.2 7.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) FlaC_arch PF05377.6 EAK88941.1 - 0.13 12.1 3.9 0.26 11.1 0.1 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) MHC_II_beta PF00969.14 EAK88941.1 - 0.13 12.2 0.9 0.73 9.8 0.6 2.3 1 1 0 1 1 1 0 Class II histocompatibility antigen, beta domain DUF745 PF05335.8 EAK88941.1 - 0.13 11.7 0.3 0.21 11.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) WEMBL PF05701.6 EAK88941.1 - 0.36 9.2 7.1 0.81 8.0 5.0 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF1690 PF07956.6 EAK88941.1 - 0.43 10.5 11.5 1.9 8.4 0.8 2.2 1 1 0 2 2 2 0 Protein of Unknown function (DUF1690) ABC2_membrane_3 PF12698.2 EAK88941.1 - 0.55 9.2 4.1 0.81 8.6 2.9 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Sec20 PF03908.8 EAK88941.1 - 0.75 9.5 9.5 0.031 13.9 1.1 2.5 2 1 0 3 3 3 0 Sec20 DNA_pol_B PF00136.16 EAK88942.1 - 1.1e-105 354.1 0.0 2.1e-105 353.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EAK88942.1 - 3.1e-22 78.8 1.2 2.2e-21 76.0 0.8 2.2 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EAK88942.1 - 7.8e-19 67.2 6.4 7.8e-19 67.2 4.4 2.6 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal zf-DNA_Pol PF08996.5 EAK88942.1 - 5.4e-07 29.1 3.1 1.3e-06 27.9 2.1 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger Peptidase_M16_C PF05193.16 EAK88943.1 - 1.2e-08 34.8 0.4 1.3e-07 31.4 0.0 2.8 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EAK88943.1 - 3.8e-08 33.2 0.0 1.2e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16 PF00675.15 EAK88945.1 - 6e-30 103.9 0.4 1.5e-29 102.7 0.3 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAK88945.1 - 2.2e-15 56.7 7.8 4.6e-09 36.2 0.1 3.9 4 0 0 4 4 4 2 Peptidase M16 inactive domain Telomere_reg-2 PF10193.4 EAK88945.1 - 0.02 15.1 0.5 0.089 13.0 0.3 2.2 1 0 0 1 1 1 0 Telomere length regulation protein Peptidase_M16 PF00675.15 EAK88946.1 - 1.9e-25 89.3 0.0 5.4e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAK88946.1 - 4.3e-11 42.8 6.9 2e-09 37.4 0.1 3.9 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16_C PF05193.16 EAK88947.1 - 7.4e-10 38.7 1.2 1.1e-05 25.1 0.2 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EAK88947.1 - 6.4e-08 32.4 3.8 2e-07 30.8 0.0 3.3 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAK88949.1 - 1.2e-09 38.0 0.1 6.6e-09 35.6 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EAK88949.1 - 1.6e-09 37.7 0.2 4.8e-09 36.1 0.2 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAK88950.1 - 1.3e-09 38.0 0.8 3.4e-08 33.3 0.1 2.5 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EAK88950.1 - 1.1e-05 25.2 0.1 3.7e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAK88951.1 - 3.3e-09 36.6 0.2 1.9e-08 34.2 0.0 2.4 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EAK88951.1 - 4e-07 29.8 0.0 2e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAK88952.1 - 2.5e-16 59.9 1.3 1.4e-10 41.1 0.0 3.6 3 0 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EAK88952.1 - 7.9e-13 48.4 0.1 3e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) zf-CCHC PF00098.18 EAK88953.1 - 5.5e-16 57.6 26.7 4.6e-06 26.3 0.7 4.5 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 EAK88953.1 - 0.0014 18.0 15.3 0.64 9.5 0.1 4.0 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 EAK88953.1 - 0.0024 17.4 32.1 0.045 13.4 1.2 5.1 5 0 0 5 5 5 3 Zinc knuckle Desulfoferrod_N PF06397.7 EAK88953.1 - 0.12 11.7 3.8 0.85 9.0 0.0 3.1 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain HTH_38 PF13936.1 EAK88953.1 - 0.17 11.4 2.1 0.36 10.4 1.5 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain E1-E2_ATPase PF00122.15 EAK88954.1 - 6.6e-22 77.6 0.1 1.1e-16 60.5 0.0 3.0 2 0 0 2 2 2 2 E1-E2 ATPase HAD PF12710.2 EAK88954.1 - 9.3e-10 38.9 0.0 4.1e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAK88954.1 - 9.8e-09 35.9 0.0 3.6e-07 30.8 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAK88954.1 - 1.3e-08 34.7 0.0 3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EAK88954.1 - 0.023 14.1 0.0 0.088 12.2 0.0 2.0 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Prismane PF03063.15 EAK88954.1 - 0.37 9.0 2.3 0.68 8.2 0.0 2.2 3 0 0 3 3 3 0 Prismane/CO dehydrogenase family DUF1467 PF07330.7 EAK88954.1 - 0.48 10.2 4.3 0.38 10.5 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) WD40 PF00400.27 EAK88956.1 - 1.7e-06 27.6 0.0 1.7 8.6 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Hira PF07569.6 EAK88956.1 - 1.5 7.9 25.6 0.011 15.0 4.9 4.6 3 1 1 4 4 4 0 TUP1-like enhancer of split TFIID_30kDa PF03540.8 EAK88957.1 - 3e-07 30.1 0.0 4.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit RNA_pol_Rpb1_4 PF05000.12 EAK88957.1 - 0.0091 15.7 0.0 0.014 15.1 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Ribosomal_S8e PF01201.17 EAK88959.1 - 3.9e-39 133.8 7.8 4.7e-38 130.3 5.4 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3959 PF13105.1 EAK88959.1 - 6.9 5.9 10.3 0.17 11.1 2.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3959) zf-UBR PF02207.15 EAK88960.1 - 3.4e-19 68.3 17.1 3.4e-19 68.3 11.9 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Trypan_PARP PF05887.6 EAK88962.1 - 0.00037 20.3 37.0 0.00037 20.3 25.6 3.1 3 1 1 4 4 4 2 Procyclic acidic repetitive protein (PARP) Yippee-Mis18 PF03226.9 EAK88963.1 - 0.00071 19.5 3.1 0.018 15.0 1.2 3.3 2 1 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 EAK88963.1 - 0.0019 17.9 0.6 0.39 10.5 0.1 2.7 2 1 0 2 2 2 2 Double zinc ribbon DNA_RNApol_7kD PF03604.8 EAK88963.1 - 0.068 12.6 1.7 2.4 7.7 0.0 3.4 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.1 EAK88963.1 - 8.4 5.7 7.2 2.6 7.3 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain CS PF04969.11 EAK88964.1 - 4.5e-18 65.5 5.2 9.2e-18 64.5 3.6 1.5 1 0 0 1 1 1 1 CS domain SGS PF05002.10 EAK88964.1 - 4.1e-11 42.4 0.8 1.1e-10 41.1 0.5 1.7 1 0 0 1 1 1 1 SGS domain Siah-Interact_N PF09032.6 EAK88964.1 - 3.1e-05 23.9 0.3 6.8e-05 22.8 0.2 1.7 1 0 0 1 1 1 1 Siah interacting protein, N terminal KSR1-SAM PF13543.1 EAK88964.1 - 0.059 13.1 0.8 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 PUA PF01472.15 EAK88966.1 - 2.3e-18 65.7 0.1 3.1e-18 65.2 0.1 1.2 1 0 0 1 1 1 1 PUA domain PUB PF09409.5 EAK88967.1 - 7.1e-24 83.3 0.6 3.7e-23 81.0 0.1 2.2 2 0 0 2 2 2 1 PUB domain UBA PF00627.26 EAK88967.1 - 1.9e-05 24.3 0.9 9.2e-05 22.1 0.0 2.6 3 0 0 3 3 3 1 UBA/TS-N domain V_ATPase_I PF01496.14 EAK88967.1 - 0.67 7.7 6.6 0.71 7.6 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PP2C_C PF07830.8 EAK88967.1 - 1 9.5 3.4 2.4 8.2 2.1 1.9 1 1 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain OmpH PF03938.9 EAK88967.1 - 3 7.7 10.6 5.1 7.0 7.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3595 PF12166.3 EAK88968.1 - 0.045 12.5 0.0 0.068 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DUF3948 PF13134.1 EAK88968.1 - 0.13 11.7 0.2 7.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) BBP1_N PF15271.1 EAK88968.1 - 0.15 12.4 4.8 0.097 13.0 1.4 1.9 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein RseA_C PF03873.8 EAK88969.1 - 7.4e-06 25.7 7.9 3.4 7.6 0.0 9.5 5 4 5 10 10 10 4 Anti sigma-E protein RseA, C-terminal domain GTP_EFTU PF00009.22 EAK88970.1 - 1.8e-33 115.5 0.0 1.3e-32 112.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EAK88970.1 - 1e-22 79.9 0.0 2.2e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EAK88970.1 - 3.4e-16 58.8 0.0 6.8e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EAK88970.1 - 2e-06 27.5 0.0 5.4e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EAK88970.1 - 5e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EAK88970.1 - 6.3e-05 23.0 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PUB PF09409.5 EAK88971.1 - 6.7e-15 54.6 3.4 6.7e-15 54.6 2.3 2.1 2 0 0 2 2 2 1 PUB domain DNA_ligase_A_M PF01068.16 EAK88972.1 - 3e-55 186.7 0.6 5.6e-55 185.8 0.4 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EAK88972.1 - 1.3e-40 139.1 1.2 2.2e-40 138.3 0.3 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EAK88972.1 - 1.4e-24 86.3 0.0 3e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EAK88972.1 - 0.02 14.5 0.3 2.2 8.0 0.0 3.0 3 0 0 3 3 3 0 DNA ligase OB-like domain WD40 PF00400.27 EAK88973.1 - 0.00018 21.2 2.1 0.00018 21.2 1.4 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF1523 PF07509.6 EAK88973.1 - 0.013 14.7 0.0 0.031 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) Hira PF07569.6 EAK88973.1 - 0.022 13.9 0.1 0.042 13.0 0.1 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split AAA PF00004.24 EAK88974.1 - 9.6e-11 42.0 5.7 2.2e-06 27.8 0.4 3.1 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) zf-CpG_bind_C PF12269.3 EAK88975.1 - 0.00095 18.7 0.2 0.0024 17.4 0.1 1.7 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain U1snRNP70_N PF12220.3 EAK88975.1 - 0.0066 16.7 2.2 0.014 15.7 1.5 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal EzrA PF06160.7 EAK88975.1 - 0.014 13.5 4.7 0.0086 14.3 1.4 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA ERM PF00769.14 EAK88975.1 - 2.2 7.7 6.6 0.46 9.9 2.1 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Siva PF05458.7 EAK88976.1 - 1.1e-05 25.0 6.5 1.3e-05 24.8 4.5 1.1 1 0 0 1 1 1 1 Cd27 binding protein (Siva) Fra10Ac1 PF09725.4 EAK88976.1 - 3 7.9 11.1 0.49 10.4 0.5 2.1 1 1 1 2 2 2 0 Folate-sensitive fragile site protein Fra10Ac1 Ctf8 PF09696.5 EAK88977.1 - 4.3e-05 23.2 0.1 5.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ctf8 Peptidase_S49_N PF08496.5 EAK88978.1 - 0.56 9.9 7.6 0.14 11.9 2.3 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3899 PF13038.1 EAK88978.1 - 2.2 8.5 6.3 33 4.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Ku_C PF03730.9 EAK88978.1 - 9.5 6.8 19.6 0.27 11.8 0.4 2.8 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm DUF773 PF05600.7 EAK88979.1 - 6.2e-09 35.1 19.1 6.1e-08 31.8 2.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF773) CK_II_beta PF01214.13 EAK88980.1 - 5e-70 234.7 0.1 6.1e-70 234.4 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit 2OG-FeII_Oxy PF03171.15 EAK88983.1 - 0.00013 22.1 0.1 0.0003 21.0 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Drf_FH1 PF06346.7 EAK88984.1 - 0.082 12.4 60.7 0.46 9.9 7.3 6.0 3 2 2 5 5 5 0 Formin Homology Region 1 DUF2209 PF09974.4 EAK88985.1 - 0.0099 15.9 0.1 0.029 14.4 0.1 1.9 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) CorA PF01544.13 EAK88985.1 - 0.019 13.9 11.9 0.024 13.7 3.5 2.7 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein TGS PF02824.16 EAK88986.1 - 1.3e-21 76.2 0.1 2.2e-21 75.4 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EAK88986.1 - 2.9e-18 65.9 0.0 6.1e-18 64.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAK88986.1 - 1.9e-11 43.4 0.0 7e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EAK88986.1 - 0.00041 20.2 0.0 0.89 9.3 0.0 2.4 2 0 0 2 2 2 2 Dynamin family ArgK PF03308.11 EAK88986.1 - 0.00069 18.4 0.2 0.0019 17.0 0.0 1.7 2 0 0 2 2 2 1 ArgK protein GTP_EFTU PF00009.22 EAK88986.1 - 0.0055 16.1 0.1 5.9 6.2 0.0 3.7 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EAK88986.1 - 0.035 14.6 0.0 0.075 13.5 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 EAK88986.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 EAK88986.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain Na_Ca_ex PF01699.19 EAK88989.1 - 1.8e-32 111.8 40.4 1.9e-22 79.3 7.1 3.3 3 0 0 3 3 3 2 Sodium/calcium exchanger protein RRM_1 PF00076.17 EAK88991.1 - 4.2e-12 45.5 5.0 6.3e-10 38.5 0.1 4.4 4 2 1 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK88991.1 - 1.7e-08 34.3 0.2 3.1e-07 30.2 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ALMS_motif PF15309.1 EAK88991.1 - 4 7.2 18.7 0.29 10.9 7.9 2.1 2 0 0 2 2 2 0 ALMS motif Sec7 PF01369.15 EAK88993.1 - 2.3e-49 167.6 5.5 2.3e-49 167.6 3.8 5.0 5 0 0 5 5 5 1 Sec7 domain DWNN PF08783.6 EAK88995.1 - 2.6e-20 72.1 4.5 7.7e-20 70.6 0.1 2.8 3 0 0 3 3 3 1 DWNN domain zf-C3HC4_2 PF13923.1 EAK88995.1 - 0.013 15.4 8.8 0.028 14.4 6.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAK88995.1 - 0.11 12.3 6.0 0.22 11.3 4.1 1.5 1 0 0 1 1 1 0 Ring finger domain PqqA PF08042.6 EAK88995.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 PqqA family zf-C3HC4_4 PF15227.1 EAK88995.1 - 0.62 9.9 9.8 0.43 10.4 4.9 2.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EAK88995.1 - 0.75 9.4 8.0 1.8 8.2 5.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK88995.1 - 2.5 7.9 7.0 4.9 6.9 4.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 EAK88995.1 - 6 6.5 7.3 11 5.7 5.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PCNA_N PF00705.13 EAK88996.1 - 4.8e-39 132.7 4.7 7.2e-39 132.1 3.3 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EAK88996.1 - 2.8e-33 114.5 0.0 3.8e-30 104.4 0.0 2.2 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 EAK88996.1 - 2.9e-10 39.3 0.8 6.2e-08 31.7 0.5 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EAK88996.1 - 7.4e-08 31.8 0.2 1.6e-07 30.6 0.1 1.6 1 1 0 1 1 1 1 Rad9 Hus1 PF04005.7 EAK88996.1 - 0.029 13.3 0.1 0.25 10.2 0.0 2.2 1 1 0 1 1 1 0 Hus1-like protein DNA_pol3_beta_2 PF02767.11 EAK88996.1 - 0.039 13.9 0.0 0.52 10.3 0.0 2.3 1 1 1 2 2 2 0 DNA polymerase III beta subunit, central domain HSP70 PF00012.15 EAK88997.1 - 1.9e-260 864.9 9.8 2.1e-260 864.8 6.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EAK88997.1 - 3.5e-15 55.4 1.6 1.7e-13 49.8 0.3 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EAK88997.1 - 0.0044 16.6 0.0 0.025 14.2 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EAK88997.1 - 0.009 15.8 3.6 1.8 8.3 0.1 3.6 3 2 0 3 3 3 2 Cell division protein FtsA Syntaxin-6_N PF09177.6 EAK88997.1 - 0.58 10.6 9.6 2.1 8.7 3.7 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cu_amine_oxid PF01179.15 EAK88998.1 - 3.8e-86 289.3 0.1 5.7e-86 288.8 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain MAM PF00629.18 EAK88998.1 - 8.2e-16 58.1 0.0 2e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 MAM domain EF-hand_7 PF13499.1 EAK88999.1 - 3.5e-10 39.8 3.9 9.3e-10 38.5 2.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EAK88999.1 - 5.6e-10 37.7 5.9 8.9e-05 21.5 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EAK88999.1 - 1.5e-09 36.9 4.4 2.3e-05 23.8 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EAK88999.1 - 1e-08 34.6 5.8 0.0014 18.1 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair COPI_assoc PF08507.5 EAK88999.1 - 4.7e-07 29.5 14.7 9.8e-07 28.5 10.2 1.5 1 0 0 1 1 1 1 COPI associated protein EF-hand_5 PF13202.1 EAK88999.1 - 1.6e-05 24.0 7.2 0.026 13.8 0.3 3.3 3 0 0 3 3 3 2 EF hand Adeno_E1B_19K PF01691.11 EAK89000.1 - 0.011 14.9 0.7 0.036 13.3 0.1 2.1 2 0 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen AAA_33 PF13671.1 EAK89000.1 - 0.23 11.3 0.0 0.48 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RPAP1_C PF08620.5 EAK89001.1 - 9.9e-28 95.8 0.1 2.4e-27 94.5 0.1 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal Sigma70_r1_2 PF00140.15 EAK89001.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Diphthamide_syn PF01866.12 EAK89003.1 - 1.9e-15 56.9 0.7 1.1e-06 28.1 0.1 2.5 2 1 0 2 2 2 2 Putative diphthamide synthesis protein ITI_HC_C PF06668.7 EAK89004.1 - 0.018 14.5 0.0 0.05 13.0 0.0 1.7 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus Ribosomal_L7Ae PF01248.21 EAK89005.1 - 1.6e-07 30.7 0.0 3.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Reo_sigmaC PF04582.7 EAK89007.1 - 0.87 8.7 7.1 4.8 6.2 0.7 2.9 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Med31 PF05669.7 EAK89008.1 - 3.1e-38 129.6 5.7 3.7e-38 129.3 4.0 1.0 1 0 0 1 1 1 1 SOH1 AAA_18 PF13238.1 EAK89010.1 - 9.7e-26 90.5 1.1 1.5e-25 89.9 0.7 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAK89010.1 - 2.3e-11 44.5 0.4 3.2e-11 44.1 0.3 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAK89010.1 - 3.5e-06 26.9 0.0 1.5e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EAK89010.1 - 1.6e-05 24.2 0.0 2.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 EAK89010.1 - 5.2e-05 23.2 0.1 0.0001 22.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EAK89010.1 - 8.5e-05 22.2 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EAK89010.1 - 9.9e-05 21.5 0.0 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EAK89010.1 - 0.00017 21.6 0.2 0.00034 20.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAK89010.1 - 0.00018 21.6 0.2 0.00024 21.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EAK89010.1 - 0.0003 20.4 0.7 0.0029 17.2 0.2 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EAK89010.1 - 0.00095 19.3 1.3 0.0066 16.6 0.4 2.4 1 1 0 1 1 1 1 RNA helicase AAA PF00004.24 EAK89010.1 - 0.0014 18.8 1.0 0.0021 18.2 0.1 1.8 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EAK89010.1 - 0.0029 17.0 0.6 0.13 11.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein SRPRB PF09439.5 EAK89010.1 - 0.0047 16.1 0.5 0.025 13.8 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EAK89010.1 - 0.0075 16.1 0.6 0.0075 16.1 0.4 1.9 1 1 1 2 2 2 1 AAA domain DUF2075 PF09848.4 EAK89010.1 - 0.0082 15.1 0.1 0.0097 14.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.4 EAK89010.1 - 0.0088 15.5 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.16 EAK89010.1 - 0.0095 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Miro PF08477.8 EAK89010.1 - 0.013 16.0 0.2 0.043 14.3 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Sigma54_activ_2 PF14532.1 EAK89010.1 - 0.016 15.2 0.0 0.099 12.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Thymidylate_kin PF02223.12 EAK89010.1 - 0.029 13.7 3.3 0.98 8.7 0.2 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_10 PF12846.2 EAK89010.1 - 0.032 13.6 0.3 0.068 12.5 0.0 1.6 2 1 0 2 2 2 0 AAA-like domain IPT PF01745.11 EAK89010.1 - 0.032 13.3 0.8 0.96 8.5 0.0 2.1 1 1 1 2 2 2 0 Isopentenyl transferase DUF4325 PF14213.1 EAK89010.1 - 0.039 13.5 0.1 0.039 13.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4325) KaiC PF06745.8 EAK89010.1 - 0.053 12.6 0.7 0.23 10.5 0.1 2.1 2 1 0 2 2 2 0 KaiC AAA_3 PF07726.6 EAK89010.1 - 0.06 12.9 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EAK89010.1 - 0.06 13.0 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EAK89010.1 - 0.061 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_2 PF07724.9 EAK89010.1 - 0.071 13.0 0.0 0.38 10.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EAK89010.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus MCM PF00493.18 EAK89010.1 - 0.086 11.6 0.1 0.15 10.8 0.0 1.6 1 1 0 1 1 1 0 MCM2/3/5 family ABC_tran PF00005.22 EAK89010.1 - 0.11 12.7 0.5 0.19 12.0 0.3 1.6 1 1 0 1 1 1 0 ABC transporter PEPCK_ATP PF01293.15 EAK89010.1 - 0.14 10.6 1.2 0.43 9.0 0.0 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase T2SE PF00437.15 EAK89010.1 - 0.18 10.6 0.8 0.33 9.8 0.1 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EAK89010.1 - 0.19 11.1 0.3 0.32 10.4 0.2 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family FAM163 PF15069.1 EAK89011.1 - 0.0019 18.7 0.5 0.003 18.1 0.4 1.3 1 0 0 1 1 1 1 FAM163 family Peptidase_M56 PF05569.6 EAK89011.1 - 0.018 14.0 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 SIT PF15330.1 EAK89011.1 - 0.022 14.8 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Shisa PF13908.1 EAK89011.1 - 0.027 14.6 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EAK89011.1 - 0.063 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 EAK89011.1 - 0.13 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family IncA PF04156.9 EAK89011.1 - 0.17 11.4 4.2 0.27 10.7 2.9 1.3 1 0 0 1 1 1 0 IncA protein CBF PF03914.12 EAK89013.1 - 2.6e-14 53.0 0.6 5e-14 52.0 0.1 1.8 2 1 0 2 2 2 1 CBF/Mak21 family SecM PF06558.7 EAK89013.1 - 0.029 14.0 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) Pkinase PF00069.20 EAK89014.1 - 5.3e-50 169.9 0.1 8.6e-48 162.7 0.1 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK89014.1 - 1.9e-32 112.3 0.0 1.4e-24 86.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PduV-EutP PF10662.4 EAK89014.1 - 0.041 13.3 0.2 0.097 12.1 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Peptidase_M54 PF07998.6 EAK89015.1 - 8.6e-17 61.5 3.3 1.1e-16 61.2 2.3 1.1 1 0 0 1 1 1 1 Peptidase family M54 DUF2268 PF10026.4 EAK89015.1 - 0.0093 15.3 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) Reprolysin_5 PF13688.1 EAK89015.1 - 0.011 15.7 0.4 0.02 14.8 0.3 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EAK89015.1 - 0.032 14.7 0.2 0.073 13.6 0.2 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAK89015.1 - 0.096 12.3 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Matrixin Arc_trans_TRASH PF08394.5 EAK89015.1 - 0.13 12.4 2.6 0.35 11.0 1.8 1.8 1 0 0 1 1 1 0 Archaeal TRASH domain Peptidase_M66 PF10462.4 EAK89015.1 - 0.26 10.1 2.2 0.69 8.7 1.5 1.8 1 1 0 1 1 1 0 Peptidase M66 ARPC4 PF05856.7 EAK89016.1 - 1.7e-60 203.2 5.7 2.8e-60 202.5 4.0 1.3 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Bromodomain PF00439.20 EAK89017.1 - 1.6e-22 79.2 2.4 2.5e-22 78.5 0.6 2.2 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.19 EAK89017.1 - 1.2e-10 41.2 0.2 2.1e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAK89017.1 - 1.6e-09 37.7 1.5 1.6e-09 37.7 1.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAK89017.1 - 1.6e-05 24.9 0.0 3.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAK89017.1 - 0.0051 16.5 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EAK89017.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EAK89017.1 - 0.035 14.2 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AUX_IAA PF02309.11 EAK89017.1 - 0.078 12.7 0.3 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 AUX/IAA family PhoH PF02562.11 EAK89017.1 - 0.16 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Pkinase PF00069.20 EAK89018.1 - 1.1e-12 47.6 0.3 4.2e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Ras PF00071.17 EAK89020.1 - 3.5e-59 198.8 0.2 4.1e-59 198.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAK89020.1 - 1.5e-20 73.8 0.1 3e-20 72.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EAK89020.1 - 6.1e-17 61.4 0.0 7.8e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAK89020.1 - 4.1e-05 22.8 0.0 5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EAK89020.1 - 0.0001 21.7 0.0 0.00033 20.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EAK89020.1 - 0.00056 19.8 0.0 0.00084 19.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Big_3_2 PF12245.3 EAK89020.1 - 0.0024 17.4 0.3 0.0062 16.0 0.1 1.8 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) AOX PF01786.12 EAK89022.1 - 1.4e-74 249.9 0.0 1.7e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Ssl1 PF04056.9 EAK89023.1 - 9.8e-33 113.3 0.1 1.4e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 EAK89023.1 - 3.4e-05 24.0 0.0 5.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.7 EAK89023.1 - 0.00034 20.5 17.7 0.00034 20.5 12.3 3.1 3 1 0 3 3 3 1 TFIIH C1-like domain MFS_1 PF07690.11 EAK89024.1 - 1.2e-37 129.4 30.7 1.7e-28 99.4 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAK89024.1 - 4e-13 48.7 17.5 1.5e-10 40.2 0.5 3.2 3 0 0 3 3 3 3 Sugar (and other) transporter ATG22 PF11700.3 EAK89024.1 - 2.9e-05 22.7 21.9 7.1e-05 21.4 4.6 2.3 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 EAK89024.1 - 0.00048 19.8 0.2 0.16 11.8 0.0 3.8 3 1 0 3 3 3 1 MFS_1 like family Phage_30_3 PF08010.6 EAK89025.1 - 0.024 14.1 0.6 0.23 10.9 0.0 2.7 3 0 0 3 3 3 0 Bacteriophage protein GP30.3 CRM1_C PF08767.6 EAK89026.1 - 3.8e-74 249.4 19.8 3.8e-74 249.4 13.7 3.5 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 EAK89026.1 - 3.9e-30 104.7 7.2 3.9e-30 104.7 5.0 4.2 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 EAK89026.1 - 4.2e-08 32.9 4.6 1.5e-07 31.1 0.4 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain WD40 PF00400.27 EAK89027.1 - 3.3e-06 26.7 3.3 0.12 12.2 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat RabGAP-TBC PF00566.13 EAK89029.1 - 3.5e-25 88.7 7.6 1.3e-24 86.8 5.0 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain IF-2B PF01008.12 EAK89031.1 - 2.1e-47 161.4 0.5 2.4e-47 161.2 0.4 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family L_lactis_RepB_C PF06430.7 EAK89031.1 - 0.0027 17.7 0.1 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 Lactococcus lactis RepB C-terminus RNR_N PF08343.5 EAK89031.1 - 0.0081 15.9 0.2 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase N-terminal PP_kinase_C PF13090.1 EAK89031.1 - 0.011 14.3 0.1 0.018 13.6 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain Utp12 PF04003.7 EAK89031.1 - 0.038 13.8 0.1 0.66 9.9 0.0 2.5 2 1 0 2 2 2 0 Dip2/Utp12 Family DUF1049 PF06305.6 EAK89032.1 - 0.15 11.5 11.3 0.24 10.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) AP2 PF00847.15 EAK89035.1 - 1.5e-06 28.2 3.5 0.025 14.7 0.0 3.4 4 0 0 4 4 4 2 AP2 domain KH_1 PF00013.24 EAK89036.1 - 0.00035 20.1 0.1 0.0012 18.4 0.0 2.0 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EAK89036.1 - 0.0042 16.7 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 EAK89036.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 KH domain AAA_11 PF13086.1 EAK89036.1 - 6.6 6.2 7.0 8.8 5.8 4.9 1.4 1 1 0 1 1 1 0 AAA domain Tim44 PF04280.10 EAK89037.1 - 1.7e-20 73.4 0.0 7.5e-19 68.1 0.0 2.4 1 1 0 1 1 1 1 Tim44-like domain Peptidase_C54 PF03416.14 EAK89038.1 - 4.2e-41 140.9 2.2 5.3e-41 140.5 1.5 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 EAK89038.1 - 0.0063 15.6 1.3 0.012 14.7 0.9 1.5 1 1 0 1 1 1 1 Peptidase family C78 PROCN PF08083.6 EAK89040.1 - 6e-204 677.1 11.9 9.8e-204 676.4 8.3 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EAK89040.1 - 1.8e-126 420.1 1.9 3.8e-126 419.0 1.3 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EAK89040.1 - 4.4e-92 305.6 2.4 1.1e-91 304.3 1.6 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EAK89040.1 - 5e-77 256.7 0.7 1.5e-76 255.2 0.5 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EAK89040.1 - 1e-67 225.9 0.1 2.6e-67 224.5 0.1 1.8 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EAK89040.1 - 1.5e-43 146.5 0.9 5.2e-43 144.8 0.6 2.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EAK89040.1 - 5.5e-41 139.1 0.3 1.2e-40 138.0 0.2 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain AMP-binding PF00501.23 EAK89041.1 - 1.4e-21 76.4 0.0 1.8e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF3386 PF11866.3 EAK89041.1 - 0.0056 15.9 1.3 0.028 13.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3386) UBA PF00627.26 EAK89041.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Cullin PF00888.17 EAK89044.1 - 7.8e-61 206.3 33.8 5.2e-60 203.6 23.5 1.9 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EAK89044.1 - 9.1e-07 28.6 0.5 3.2e-06 26.8 0.3 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain zf-C2H2_jaz PF12171.3 EAK89045.1 - 4.9e-07 29.7 0.7 9.7e-07 28.7 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EAK89045.1 - 0.00057 19.9 2.1 0.002 18.1 1.5 2.0 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EAK89045.1 - 0.0013 18.8 0.3 0.0025 17.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CCDC84 PF14968.1 EAK89045.1 - 0.044 13.2 4.5 0.071 12.6 3.1 1.4 1 1 0 1 1 1 0 Coiled coil protein 84 DUF1677 PF07911.8 EAK89045.1 - 0.11 12.6 0.3 1.9 8.7 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1677) ADK PF00406.17 EAK89046.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase Paf1 PF03985.8 EAK89046.1 - 0.15 10.8 0.0 0.15 10.8 0.0 2.2 2 1 1 3 3 3 0 Paf1 POP1 PF06978.6 EAK89047.1 - 8.5e-49 165.7 7.2 8.5e-49 165.7 5.0 1.7 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EAK89047.1 - 2.2e-07 30.5 0.2 1.5e-05 24.7 0.2 2.8 1 1 0 1 1 1 1 POPLD (NUC188) domain GCV_T_C PF08669.6 EAK89047.1 - 0.002 18.1 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF2281 PF10047.4 EAK89047.1 - 0.053 13.8 0.0 0.4 11.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2281) HSCB_C PF07743.8 EAK89048.1 - 3.2e-06 27.5 0.6 6.3e-06 26.5 0.4 1.4 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EAK89048.1 - 2.2e-05 24.0 0.1 7.3e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain Inhibitor_I24 PF10465.4 EAK89048.1 - 0.13 11.9 0.9 0.32 10.7 0.5 1.7 1 1 1 2 2 2 0 PinA peptidase inhibitor TH1 PF04858.8 EAK89049.1 - 1.3e-11 43.3 0.5 1.4e-05 23.4 0.0 4.4 5 0 0 5 5 5 4 TH1 protein Ank_2 PF12796.2 EAK89050.1 - 0.0054 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAK89050.1 - 0.034 14.4 0.0 0.086 13.1 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAK89050.1 - 0.076 13.5 0.0 0.27 11.8 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Herpes_UL52 PF03121.10 EAK89051.1 - 1.3e-12 47.2 2.2 3.7e-12 45.7 0.2 2.4 2 0 0 2 2 2 1 Herpesviridae UL52/UL70 DNA primase DUF3528 PF12045.3 EAK89051.1 - 0.054 13.6 0.0 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3528) TF_Zn_Ribbon PF08271.7 EAK89052.1 - 7.2e-05 22.0 2.6 0.0002 20.6 1.8 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 EAK89052.1 - 0.00088 18.6 3.6 0.0022 17.3 2.5 1.7 1 0 0 1 1 1 1 A2L zinc ribbon domain RRN7 PF11781.3 EAK89052.1 - 0.046 13.2 3.3 0.084 12.3 2.0 1.7 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Phage_connect_1 PF05135.8 EAK89052.1 - 0.17 12.0 4.9 0.06 13.5 0.9 2.2 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein TLD PF07534.11 EAK89053.1 - 1.3e-26 93.2 0.2 3.3e-26 91.9 0.1 1.8 1 0 0 1 1 1 1 TLD Hydrolase PF00702.21 EAK89054.1 - 2.6e-16 60.7 0.0 2.6e-15 57.4 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAK89054.1 - 5.6e-15 55.9 0.0 1.4e-14 54.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EAK89054.1 - 5.6e-12 45.1 0.0 5.6e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EAK89054.1 - 8.3e-05 22.4 0.1 0.00035 20.4 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAK89054.1 - 0.0002 21.0 0.5 0.0002 21.0 0.3 3.7 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase CENP-C_C PF11699.3 EAK89055.1 - 0.00068 19.5 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EAK89055.1 - 0.17 11.3 0.0 0.54 9.8 0.0 1.8 1 0 0 1 1 1 0 Cupin domain DnaJ PF00226.26 EAK89056.1 - 8.2e-23 79.9 0.1 1.5e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.15 EAK89056.1 - 5.8e-05 22.7 0.0 0.00017 21.1 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 EAK89056.1 - 0.0029 17.4 1.1 0.006 16.3 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Fig1 PF12351.3 EAK89056.1 - 0.043 13.7 0.3 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DAGK_acc PF00609.14 EAK89058.1 - 3.9e-37 127.8 0.1 1.8e-14 54.2 0.0 3.5 3 0 0 3 3 3 3 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EAK89058.1 - 7.1e-24 83.7 0.0 1.3e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 EAK89058.1 - 6e-10 38.7 26.3 4.8e-06 26.1 5.4 3.0 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF498 PF04430.9 EAK89059.1 - 0.034 13.7 0.0 0.099 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) RRM_1 PF00076.17 EAK89063.1 - 1.4e-17 63.0 0.2 2.7e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK89063.1 - 9e-17 60.6 0.3 9.1e-08 31.8 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK89063.1 - 8e-10 38.5 0.0 1.5e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Methyltransf_16 PF10294.4 EAK89064.1 - 1.3e-10 41.0 0.1 5.8e-10 38.9 0.1 2.0 1 1 0 1 1 1 1 Putative methyltransferase DUF2866 PF11065.3 EAK89064.1 - 0.00035 20.4 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2866) PrmA PF06325.8 EAK89064.1 - 0.02 14.0 0.0 0.035 13.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RabGAP-TBC PF00566.13 EAK89065.1 - 3.5e-48 163.9 7.1 5.5e-48 163.2 4.9 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Histone PF00125.19 EAK89066.1 - 7.5e-33 112.4 0.4 1.2e-32 111.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EAK89066.1 - 0.00017 21.6 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EAK89066.1 - 0.012 15.6 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Proteasome PF00227.21 EAK89067.1 - 1.1e-49 168.2 0.2 1.4e-49 167.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit TPR_11 PF13414.1 EAK89068.1 - 9.1e-13 47.6 1.6 4.1e-05 23.1 0.0 3.7 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EAK89068.1 - 1.1e-09 37.4 0.5 0.039 13.8 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAK89068.1 - 5e-08 32.2 4.9 0.07 12.7 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAK89068.1 - 1.6e-06 28.6 0.0 0.00076 20.0 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAK89068.1 - 2.2e-05 24.7 0.1 0.0083 16.4 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAK89068.1 - 5.7e-05 23.0 1.8 0.027 14.6 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAK89068.1 - 0.00017 21.4 1.0 1.1 9.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAK89068.1 - 0.14 12.0 2.2 0.78 9.6 0.0 3.1 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Thioredoxin PF00085.15 EAK89070.1 - 1.1e-07 31.4 0.0 2.9e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Peptidase_M24 PF00557.19 EAK89072.1 - 4.8e-22 78.5 0.0 7.2e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 eIF3_subunit PF08597.5 EAK89073.1 - 5.3e-07 29.4 8.6 1.3e-06 28.1 5.9 1.7 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit CemA PF03040.9 EAK89073.1 - 0.47 10.0 6.4 1.1 8.8 0.2 2.1 1 1 1 2 2 2 0 CemA family GYF PF02213.11 EAK89074.1 - 2.6e-13 49.3 0.1 1.6e-12 46.8 0.0 2.4 2 0 0 2 2 2 1 GYF domain IQ PF00612.22 EAK89074.1 - 0.066 12.8 1.0 0.16 11.7 0.7 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ribosomal_S13 PF00416.17 EAK89075.1 - 1.5e-39 134.7 3.3 1.8e-39 134.4 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EAK89075.1 - 0.033 12.7 0.0 0.043 12.3 0.0 1.2 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EAK89075.1 - 0.064 13.3 0.2 0.3 11.1 0.1 2.1 1 1 1 2 2 2 0 Helix-hairpin-helix motif Ufd2P_core PF10408.4 EAK89077.1 - 7.7e-168 559.6 31.3 1.2e-167 558.9 21.7 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EAK89077.1 - 9.3e-24 83.1 1.9 5.6e-23 80.7 1.0 2.4 2 0 0 2 2 2 1 U-box domain DUF2999 PF11212.3 EAK89077.1 - 0.04 13.9 0.1 0.13 12.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) Spore_YhaL PF14147.1 EAK89078.1 - 1.7 8.1 4.6 2.8 7.4 3.2 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL Shisa PF13908.1 EAK89078.1 - 6.7 6.8 13.1 7.9 6.6 9.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Nup96 PF12110.3 EAK89079.1 - 6.6e-43 146.8 1.5 1.2e-42 146.0 1.1 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EAK89079.1 - 1.7e-38 131.6 0.1 8.4e-38 129.3 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin autopeptidase Rhabdo_ncap_2 PF03216.8 EAK89079.1 - 0.18 10.4 0.2 0.3 9.7 0.1 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleoprotein Prenyltrans PF00432.16 EAK89080.1 - 3.2e-19 68.1 0.0 8.2e-09 34.8 0.0 4.0 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EAK89080.1 - 1.6e-06 28.4 0.0 4.4e-05 23.8 0.0 2.3 1 1 1 2 2 2 1 Prenyltransferase-like AAA_22 PF13401.1 EAK89082.1 - 0.0026 17.9 0.0 0.04 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EAK89082.1 - 0.027 15.2 0.1 0.29 11.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EAK89082.1 - 0.045 13.7 0.0 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 EAK89082.1 - 0.055 13.1 0.0 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 EAK89082.1 - 0.081 12.5 0.0 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EAK89082.1 - 0.18 11.2 0.0 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain PARG_cat PF05028.9 EAK89083.1 - 0.061 12.5 0.2 0.083 12.1 0.2 1.1 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) AAA PF00004.24 EAK89084.1 - 3.5e-06 27.2 0.1 4.4e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EAK89084.1 - 0.043 13.5 0.3 0.055 13.1 0.2 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EAK89084.1 - 0.048 13.5 0.6 0.068 13.0 0.4 1.3 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 EAK89085.1 - 2.9e-11 42.7 9.9 0.0058 16.4 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat UTP15_C PF09384.5 EAK89085.1 - 6.8e-08 32.3 1.4 1.9e-07 30.8 1.0 1.8 1 1 0 1 1 1 1 UTP15 C terminal Utp13 PF08625.6 EAK89085.1 - 0.1 12.2 2.6 0.59 9.7 1.8 2.3 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain SynMuv_product PF06047.6 EAK89086.1 - 2.2e-49 165.5 4.6 2.2e-49 165.5 3.2 1.6 2 0 0 2 2 2 1 Ras-induced vulval development antagonist Proteasome PF00227.21 EAK89087.1 - 7.5e-49 165.6 0.3 9.6e-49 165.2 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAK89087.1 - 6.5e-14 50.9 0.1 1.1e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF507 PF04368.8 EAK89087.1 - 0.057 13.0 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF507) PTPLA PF04387.9 EAK89088.1 - 7.2e-56 188.1 10.8 1.1e-55 187.4 7.5 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA ketoacyl-synt PF00109.21 EAK89089.1 - 5.9e-261 861.4 1.0 1.9e-87 292.9 0.0 3.7 3 0 0 3 3 3 3 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EAK89089.1 - 7.7e-161 530.7 0.0 1.5e-56 190.8 0.0 4.3 4 0 0 4 4 4 3 KR domain Acyl_transf_1 PF00698.16 EAK89089.1 - 4.7e-134 446.7 0.0 1.1e-51 176.0 0.0 3.3 3 0 0 3 3 3 3 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EAK89089.1 - 7.4e-127 416.2 0.4 4e-42 142.8 0.0 3.5 3 0 0 3 3 3 3 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EAK89089.1 - 3.9e-126 417.2 0.0 5e-42 143.6 0.0 4.7 4 0 0 4 4 4 3 short chain dehydrogenase ADH_zinc_N PF00107.21 EAK89089.1 - 1.4e-74 247.7 0.0 9.1e-23 80.2 0.0 4.5 4 0 0 4 4 4 3 Zinc-binding dehydrogenase PS-DH PF14765.1 EAK89089.1 - 9.3e-69 231.8 0.0 3.3e-27 95.4 0.0 4.2 3 2 0 3 3 3 3 Polyketide synthase dehydratase AMP-binding PF00501.23 EAK89089.1 - 1.7e-65 221.0 0.0 2.1e-37 128.4 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 EAK89089.1 - 2e-64 216.8 0.0 2.7e-57 193.5 0.0 4.5 4 0 0 4 4 4 2 Male sterility protein PP-binding PF00550.20 EAK89089.1 - 3.7e-56 187.2 7.0 1.2e-15 57.4 0.2 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site Epimerase PF01370.16 EAK89089.1 - 2e-30 105.9 0.0 2.9e-08 33.4 0.0 4.6 4 0 0 4 4 4 4 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 EAK89089.1 - 4.2e-22 77.9 7.5 3e-06 26.9 0.1 4.3 4 0 0 4 4 3 3 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EAK89089.1 - 6.8e-19 69.0 0.0 0.00023 22.0 0.0 3.9 3 0 0 3 3 3 3 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.10 EAK89089.1 - 6.4e-15 54.8 3.6 0.001 18.0 0.0 4.4 4 0 0 4 4 4 3 Polysaccharide biosynthesis protein Thiolase_N PF00108.18 EAK89089.1 - 4e-11 42.3 9.2 0.0013 17.7 1.1 3.8 3 0 0 3 3 3 3 Thiolase, N-terminal domain NAD_binding_10 PF13460.1 EAK89089.1 - 3.2e-05 24.0 0.4 23 4.9 0.0 6.7 7 0 0 7 7 7 0 NADH(P)-binding Shikimate_DH PF01488.15 EAK89089.1 - 0.0057 16.7 2.7 5.7 7.0 0.1 3.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EAK89089.1 - 0.0076 15.4 3.7 36 3.4 0.0 5.6 5 3 0 5 5 5 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Asp_protease PF09668.5 EAK89090.1 - 1.7e-57 192.2 1.1 2.4e-57 191.8 0.2 1.6 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.1 EAK89090.1 - 1.3e-10 41.6 0.0 2.7e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EAK89090.1 - 3.7e-07 29.9 0.0 1.1e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.26 EAK89090.1 - 3.6e-06 26.6 0.0 7.3e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 EAK89090.1 - 9.3e-06 25.6 0.1 1.5e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EAK89090.1 - 0.0002 21.1 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A3 PF02160.10 EAK89090.1 - 0.0017 18.0 0.3 0.0017 18.0 0.2 2.2 2 0 0 2 2 2 1 Cauliflower mosaic virus peptidase (A3) Rap1_C PF11626.3 EAK89090.1 - 0.025 14.4 0.0 0.075 12.9 0.0 1.8 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ubiquitin PF00240.18 EAK89090.1 - 0.034 13.5 0.1 0.094 12.1 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin family IFP_35_N PF07334.8 EAK89091.1 - 1 9.3 5.3 3.6 7.6 0.1 2.6 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PolyA_pol PF01743.15 EAK89092.1 - 3.3e-20 72.5 0.1 1.4e-19 70.5 0.1 2.1 1 1 0 1 1 1 1 Poly A polymerase head domain DUF1374 PF07118.6 EAK89092.1 - 0.0048 16.9 1.0 0.028 14.5 0.7 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1374) PolyA_pol_RNAbd PF12627.2 EAK89092.1 - 0.021 14.3 0.0 0.075 12.6 0.0 2.0 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A BLOC1_2 PF10046.4 EAK89093.1 - 0.23 11.6 3.3 0.22 11.6 0.7 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Myosin_head PF00063.16 EAK89094.1 - 3.1e-35 121.4 6.1 3.8e-34 117.8 0.4 3.2 1 1 0 2 2 2 2 Myosin head (motor domain) RCC1 PF00415.13 EAK89094.1 - 1e-31 108.8 0.5 8.3e-09 35.5 0.0 6.3 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.22 EAK89094.1 - 1.8e-13 48.8 30.8 7.3e-05 22.0 0.3 7.6 7 0 0 7 7 7 4 IQ calmodulin-binding motif RCC1_2 PF13540.1 EAK89094.1 - 2e-11 43.1 17.9 1.7e-06 27.5 0.1 6.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BK_channel_a PF03493.13 EAK89096.1 - 6.1e-16 58.2 0.3 2e-06 27.6 0.0 4.0 3 0 0 3 3 3 3 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 EAK89096.1 - 3.8e-12 45.7 9.4 3.8e-12 45.7 6.5 2.7 2 0 0 2 2 2 1 Ion channel 2OG-FeII_Oxy_3 PF13640.1 EAK89097.1 - 4.5e-11 43.1 0.0 9.9e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EAK89097.1 - 2.7e-06 26.8 0.0 5.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EAK89097.1 - 0.015 15.5 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 EAK89097.1 - 0.054 13.7 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase WD40 PF00400.27 EAK89098.1 - 6e-12 44.9 2.4 0.00049 19.8 0.2 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat HUN PF08729.5 EAK89099.1 - 5.8e-08 32.4 3.2 1.9e-07 30.8 2.2 2.0 1 0 0 1 1 1 1 HPC2 and ubinuclein domain ATG16 PF08614.6 EAK89101.1 - 1.1e-05 25.3 8.5 1.9e-05 24.5 5.8 1.6 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Cluap1 PF10234.4 EAK89101.1 - 0.00094 18.4 4.1 0.00099 18.3 2.8 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 Gly_acyl_tr_C PF08444.5 EAK89101.1 - 0.0052 16.7 0.1 0.0081 16.1 0.1 1.3 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Filament PF00038.16 EAK89101.1 - 0.0068 15.9 4.7 0.0068 15.9 3.2 1.1 1 0 0 1 1 1 1 Intermediate filament protein DUF876 PF05936.7 EAK89101.1 - 0.0079 14.6 0.4 0.0082 14.6 0.3 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF876) Reo_sigmaC PF04582.7 EAK89101.1 - 0.012 14.7 0.8 0.014 14.6 0.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EAK89101.1 - 0.018 13.7 7.5 0.02 13.5 5.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Vps51 PF08700.6 EAK89101.1 - 0.018 14.8 6.5 0.25 11.2 1.4 2.4 1 1 0 2 2 2 0 Vps51/Vps67 HAUS-augmin3 PF14932.1 EAK89101.1 - 0.019 14.1 6.8 0.025 13.7 4.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Orbi_VP5 PF00901.12 EAK89101.1 - 0.024 12.8 1.2 0.025 12.7 0.9 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 C9orf72-like PF15019.1 EAK89101.1 - 0.025 13.8 1.8 0.027 13.7 1.2 1.1 1 0 0 1 1 1 0 C9orf72-like protein family DUF948 PF06103.6 EAK89101.1 - 0.038 13.8 1.8 0.061 13.1 0.5 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) YjcZ PF13990.1 EAK89101.1 - 0.039 13.0 1.7 0.042 12.9 1.2 1.1 1 0 0 1 1 1 0 YjcZ-like protein DUF4601 PF15373.1 EAK89101.1 - 0.04 12.7 0.7 0.043 12.6 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) UBN2 PF14223.1 EAK89101.1 - 0.041 13.6 2.5 0.1 12.4 0.4 2.1 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type Death_2 PF14786.1 EAK89101.1 - 0.041 13.5 0.1 0.045 13.4 0.1 1.2 1 0 0 1 1 1 0 Tube Death domain DXP_synthase_N PF13292.1 EAK89101.1 - 0.044 12.7 2.3 0.37 9.6 0.1 2.1 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase V-SNARE PF05008.10 EAK89101.1 - 0.051 13.7 7.6 0.15 12.2 5.3 1.8 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DUF1664 PF07889.7 EAK89101.1 - 0.06 13.1 1.9 0.094 12.5 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Mnd1 PF03962.10 EAK89101.1 - 0.063 12.9 4.0 0.094 12.3 2.8 1.3 1 0 0 1 1 1 0 Mnd1 family Arch_ATPase PF01637.13 EAK89101.1 - 0.065 12.9 1.3 0.069 12.8 0.9 1.1 1 0 0 1 1 1 0 Archaeal ATPase DUF3510 PF12022.3 EAK89101.1 - 0.076 13.1 4.7 1.8 8.6 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) IncA PF04156.9 EAK89101.1 - 0.088 12.3 6.5 0.1 12.1 4.5 1.1 1 0 0 1 1 1 0 IncA protein SAP PF02037.22 EAK89101.1 - 0.11 11.9 1.0 0.28 10.7 0.7 1.7 1 0 0 1 1 1 0 SAP domain FEZ PF07763.8 EAK89101.1 - 0.15 11.7 6.5 0.18 11.4 4.5 1.0 1 0 0 1 1 1 0 FEZ-like protein TMPIT PF07851.8 EAK89101.1 - 0.15 11.0 2.6 0.18 10.8 1.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Prefoldin PF02996.12 EAK89101.1 - 0.2 11.3 4.9 0.19 11.3 2.0 1.9 2 0 0 2 2 2 0 Prefoldin subunit Rep_fac_C PF08542.6 EAK89101.1 - 0.21 11.6 2.4 1.5 8.8 1.6 2.3 1 1 0 1 1 1 0 Replication factor C C-terminal domain MutS_II PF05188.12 EAK89101.1 - 0.23 11.5 2.6 0.34 10.9 1.8 1.3 1 1 0 1 1 1 0 MutS domain II DUF1128 PF06569.6 EAK89101.1 - 0.24 11.1 4.5 0.33 10.7 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) DUF2175 PF09943.4 EAK89101.1 - 0.24 11.4 2.6 0.28 11.2 0.4 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Mst1_SARAH PF11629.3 EAK89101.1 - 0.4 10.5 4.3 0.55 10.0 0.1 3.0 3 1 0 3 3 3 0 C terminal SARAH domain of Mst1 Lge1 PF11488.3 EAK89101.1 - 0.46 10.7 4.3 1.4 9.1 2.6 2.0 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF342 PF03961.8 EAK89101.1 - 0.87 7.9 6.3 0.92 7.8 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MCC-bdg_PDZ PF10506.4 EAK89101.1 - 1.5 8.6 6.2 10 6.0 0.5 2.3 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome AAA_23 PF13476.1 EAK89101.1 - 2.8 8.2 11.6 3.5 7.9 8.1 1.1 1 0 0 1 1 1 0 AAA domain DUF16 PF01519.11 EAK89101.1 - 3.3 7.9 7.6 5.9 7.1 5.3 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 CAAP1 PF15335.1 EAK89101.1 - 6.9 6.9 8.9 37 4.6 3.9 2.9 2 1 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 TMF_DNA_bd PF12329.3 EAK89101.1 - 7.4 6.4 13.3 5.4 6.8 5.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 EAK89101.1 - 8.4 6.8 10.4 2.2 8.7 3.4 2.7 2 2 1 3 3 3 0 SlyX Prefoldin_2 PF01920.15 EAK89101.1 - 8.7 6.1 14.4 9.8 6.0 6.2 2.7 1 1 1 2 2 2 0 Prefoldin subunit SAP30_Sin3_bdg PF13867.1 EAK89102.1 - 0.0068 16.2 0.2 0.018 14.8 0.2 1.7 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Scm3 PF10384.4 EAK89102.1 - 0.045 13.2 0.1 0.14 11.6 0.1 1.9 1 1 0 1 1 1 0 Centromere protein Scm3 TCTP PF00838.12 EAK89103.1 - 9.2e-42 142.8 3.7 1.1e-41 142.6 2.6 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein TroA PF01297.12 EAK89103.1 - 0.092 11.9 0.3 0.33 10.1 0.0 1.7 2 0 0 2 2 2 0 Periplasmic solute binding protein family Zip PF02535.17 EAK89104.1 - 0.44 9.4 8.5 0.094 11.7 3.6 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter PRP38 PF03371.10 EAK89105.1 - 5.4e-52 175.8 0.5 7.2e-52 175.4 0.4 1.1 1 0 0 1 1 1 1 PRP38 family Collar PF07484.7 EAK89105.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Phage Tail Collar Domain Acetyltransf_1 PF00583.19 EAK89107.1 - 5.6e-09 35.9 0.0 9.8e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAK89107.1 - 0.00025 21.1 0.1 0.0013 18.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAK89107.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAK89107.1 - 0.046 13.8 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DSPc PF00782.15 EAK89108.1 - 6.8e-08 32.1 0.0 1.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAK89108.1 - 0.00087 18.7 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EAK89108.1 - 0.0033 17.7 0.0 0.0072 16.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 EAK89108.1 - 0.0099 15.3 0.1 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EAK89108.1 - 0.066 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate RNA_POL_M_15KD PF02150.11 EAK89109.1 - 3.3e-07 29.8 8.8 3.3e-07 29.8 6.1 3.6 3 1 1 4 4 4 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 EAK89109.1 - 4.6e-07 29.3 0.5 4.6e-07 29.3 0.4 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.2 EAK89109.1 - 0.002 17.8 9.4 0.086 12.6 2.1 2.7 2 1 0 2 2 2 2 Double zinc ribbon A2L_zn_ribbon PF08792.5 EAK89109.1 - 0.036 13.5 13.3 0.19 11.2 0.1 4.1 3 1 1 4 4 4 0 A2L zinc ribbon domain RecR PF02132.10 EAK89109.1 - 0.15 11.5 7.3 0.3 10.5 0.1 3.6 3 1 1 4 4 4 0 RecR protein DUF3795 PF12675.2 EAK89109.1 - 0.18 12.0 6.3 1.3 9.2 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) DUF3279 PF11682.3 EAK89109.1 - 0.41 10.2 4.6 1.6 8.2 2.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3279) YecR PF13992.1 EAK89109.1 - 0.78 9.9 4.2 1.5 9.0 0.2 2.3 2 0 0 2 2 2 0 YecR-like lipoprotein Spt4 PF06093.8 EAK89109.1 - 1.5 8.7 5.2 1.6 8.6 2.1 2.2 2 1 0 2 2 2 0 Spt4/RpoE2 zinc finger DUF3268 PF11672.3 EAK89109.1 - 1.7 8.7 5.2 16 5.6 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3268) Elf1 PF05129.8 EAK89109.1 - 2.2 8.0 7.1 1.8 8.3 0.1 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 EAK89109.1 - 3.3 7.5 11.8 41 4.0 2.7 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.1 EAK89109.1 - 4.1 7.7 9.6 2.2 8.6 0.9 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 EAK89109.1 - 4.3 6.6 12.4 6.2 6.1 0.4 4.2 4 0 0 4 4 4 0 zinc-ribbon domain zf-AN1 PF01428.11 EAK89109.1 - 9.6 6.1 12.3 14 5.6 0.0 4.1 3 1 1 4 4 4 0 AN1-like Zinc finger EGF_CA PF07645.10 EAK89110.1 - 2.4e-56 187.4 133.1 3.3e-10 39.7 6.0 10.0 10 0 0 10 10 10 8 Calcium-binding EGF domain cEGF PF12662.2 EAK89110.1 - 5.1e-46 153.9 59.4 1.1e-08 34.6 0.3 9.1 8 0 0 8 8 8 8 Complement Clr-like EGF-like FXa_inhibition PF14670.1 EAK89110.1 - 3.5e-30 103.8 129.1 9.3e-08 32.0 6.2 9.4 9 0 0 9 9 9 7 Coagulation Factor Xa inhibitory site EGF PF00008.22 EAK89110.1 - 7.1e-18 64.2 106.9 6.1e-05 22.8 3.6 10.4 9 2 0 9 9 9 8 EGF-like domain EGF_3 PF12947.2 EAK89110.1 - 3.9e-07 29.9 105.4 0.0047 16.8 3.2 10.3 9 2 0 9 9 9 7 EGF domain hEGF PF12661.2 EAK89110.1 - 0.039 14.0 0.4 0.039 14.0 0.3 7.1 7 0 0 7 7 7 0 Human growth factor-like EGF CK_II_beta PF01214.13 EAK89111.1 - 3.1e-66 222.3 0.0 5.4e-66 221.6 0.0 1.4 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HupE_UreJ PF04955.7 EAK89114.1 - 0.066 12.5 4.1 0.11 11.7 1.2 2.1 2 0 0 2 2 2 0 HupE / UreJ protein DUF3959 PF13105.1 EAK89115.1 - 1.7 7.9 13.7 1.7 7.9 8.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3959) Trypan_PARP PF05887.6 EAK89115.1 - 2.6 7.8 15.9 0.094 12.5 6.9 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Cse1 PF08506.5 EAK89116.1 - 9.3e-41 139.6 2.2 9.2e-39 133.0 1.5 2.4 1 1 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 EAK89116.1 - 2.6e-36 124.8 2.8 2.6e-36 124.8 2.0 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EAK89116.1 - 6.4e-11 42.0 0.0 2.9e-10 39.9 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain PG_binding_1 PF01471.13 EAK89118.1 - 0.035 14.0 0.1 0.1 12.5 0.0 1.8 1 1 1 2 2 2 0 Putative peptidoglycan binding domain TT_ORF2 PF02957.10 EAK89119.1 - 0.022 15.4 1.7 0.037 14.7 1.2 1.3 1 0 0 1 1 1 0 TT viral ORF2 BTV_NS2 PF04514.7 EAK89119.1 - 0.037 12.9 6.5 0.057 12.2 4.5 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RXT2_N PF08595.6 EAK89119.1 - 0.045 13.5 5.3 0.077 12.7 3.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.4 EAK89119.1 - 0.37 9.4 13.4 0.63 8.6 9.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 EAK89119.1 - 0.5 10.7 10.3 1.7 9.0 7.1 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GEMIN8 PF15348.1 EAK89119.1 - 0.9 9.5 7.3 2.8 7.9 3.3 2.4 2 1 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 CENP-B_dimeris PF09026.5 EAK89119.1 - 0.99 9.6 11.8 2 8.7 8.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PPP4R2 PF09184.6 EAK89119.1 - 1.2 8.6 13.5 2.1 7.8 9.4 1.3 1 0 0 1 1 1 0 PPP4R2 Nucleoplasmin PF03066.10 EAK89119.1 - 2.2 7.7 10.6 4.2 6.8 7.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin ANAPC15 PF15243.1 EAK89119.1 - 2.7 8.1 13.5 6.4 6.9 9.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 AAA_13 PF13166.1 EAK89120.1 - 0.062 11.7 20.7 0.24 9.8 13.2 2.0 1 1 1 2 2 2 0 AAA domain PTPS PF01242.14 EAK89120.1 - 0.09 12.4 1.9 3.1 7.5 0.1 2.3 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase Peptidase_A4 PF01828.12 EAK89120.1 - 0.12 11.4 0.1 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase A4 family CRAL_TRIO_2 PF13716.1 EAK89120.1 - 0.25 11.2 9.0 33 4.3 6.1 2.4 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain HSCB_C PF07743.8 EAK89120.1 - 4.5 7.8 7.0 6.3 7.3 0.1 3.1 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain DUF1096 PF06493.6 EAK89122.1 - 0.11 12.4 3.6 0.25 11.2 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1096) BLOC1_2 PF10046.4 EAK89125.1 - 0.002 18.1 1.2 0.2 11.7 0.1 2.3 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Condensin2nSMC PF12422.3 EAK89125.1 - 0.012 15.2 1.1 0.022 14.5 0.8 1.4 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Sigma70_ner PF04546.8 EAK89125.1 - 0.017 14.7 0.4 0.029 13.9 0.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DivIC PF04977.10 EAK89125.1 - 0.019 14.4 0.1 0.11 12.0 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator Prefoldin PF02996.12 EAK89125.1 - 0.055 13.1 0.5 0.055 13.1 0.4 2.0 3 0 0 3 3 2 0 Prefoldin subunit DASH_Dad3 PF08656.5 EAK89125.1 - 0.06 13.0 5.3 1.7 8.3 0.1 2.9 2 1 1 3 3 3 0 DASH complex subunit Dad3 Trns_repr_metal PF02583.12 EAK89125.1 - 0.077 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor FlaC_arch PF05377.6 EAK89125.1 - 0.097 12.5 0.8 0.22 11.4 0.2 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ski_Sno PF02437.12 EAK89125.1 - 0.14 11.7 1.0 2.3 7.8 0.1 2.2 2 0 0 2 2 2 0 SKI/SNO/DAC family DUF4279 PF14106.1 EAK89125.1 - 0.15 11.9 0.7 5.1 7.0 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4279) Synaptonemal_3 PF15191.1 EAK89125.1 - 0.21 11.3 2.7 0.88 9.3 0.7 2.3 2 1 0 2 2 2 0 Synaptonemal complex central element protein 3 DUF4371 PF14291.1 EAK89125.1 - 0.26 10.8 3.0 0.34 10.4 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) DUF342 PF03961.8 EAK89125.1 - 0.34 9.2 5.1 0.37 9.1 2.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) FlxA PF14282.1 EAK89125.1 - 0.39 10.6 3.0 0.26 11.2 0.3 2.0 2 0 0 2 2 2 0 FlxA-like protein YvrJ PF12841.2 EAK89125.1 - 0.65 9.3 4.4 0.79 9.0 0.9 2.5 2 0 0 2 2 2 0 YvrJ protein family Med9 PF07544.8 EAK89125.1 - 2.3 8.0 5.5 0.32 10.7 0.4 2.1 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TMF_DNA_bd PF12329.3 EAK89125.1 - 2.8 7.8 8.8 0.22 11.3 1.6 2.4 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding Cep57_MT_bd PF06657.8 EAK89125.1 - 3.3 7.7 6.0 3 7.8 2.7 2.2 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ETRAMP PF09716.5 EAK89126.1 - 0.18 11.7 2.6 12 5.9 0.4 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF325 PF03804.8 EAK89127.1 - 0.042 13.5 0.2 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Viral domain of unknown function Peptidase_C34 PF05413.6 EAK89129.1 - 0.11 12.5 0.2 0.39 10.7 0.0 2.0 2 1 0 2 2 2 0 Putative closterovirus papain-like endopeptidase RNase_P_p30 PF01876.11 EAK89130.1 - 1.4e-37 128.2 0.1 2.4e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 RNase P subunit p30 START PF01852.14 EAK89131.1 - 1.6e-07 30.8 0.1 1.1e-06 28.1 0.1 2.1 1 1 0 1 1 1 1 START domain DUF3074 PF11274.3 EAK89131.1 - 2.8 7.5 8.3 15 5.1 0.2 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF3074) Neurensin PF14927.1 EAK89132.1 - 0.0083 15.5 1.5 0.26 10.6 0.4 2.7 2 0 0 2 2 2 1 Neurensin DUF2730 PF10805.3 EAK89132.1 - 0.014 15.1 0.6 3.6 7.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF308 PF03729.8 EAK89132.1 - 0.054 13.4 10.0 0.04 13.9 3.2 2.4 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF202 PF02656.10 EAK89132.1 - 0.41 10.8 2.6 18 5.6 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Glyco_hydro_31 PF01055.21 EAK89133.1 - 2.1e-90 303.7 0.6 1e-48 166.3 0.5 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EAK89133.1 - 4.5e-15 55.2 0.3 2.1e-14 53.1 0.2 2.3 1 0 0 1 1 1 1 Galactose mutarotase-like RNA_pol_Rpb1_5 PF04998.12 EAK89133.1 - 0.25 10.5 4.9 0.051 12.8 0.3 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 DIX PF00778.12 EAK89134.1 - 9.4e-05 22.0 0.2 0.00022 20.9 0.1 1.6 1 1 0 1 1 1 1 DIX domain Mito_fiss_reg PF05308.6 EAK89134.1 - 0.00041 19.8 11.5 0.00057 19.3 8.0 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator CAP_N PF01213.14 EAK89134.1 - 0.83 8.8 14.9 1.2 8.3 10.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mucin PF01456.12 EAK89135.1 - 0.42 10.3 60.6 0.96 9.2 42.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein E_Pc_C PF06752.7 EAK89135.1 - 0.48 9.8 29.3 1 8.7 20.3 1.5 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus IER PF05760.7 EAK89135.1 - 0.49 10.2 12.5 1.2 9.0 8.7 1.5 1 0 0 1 1 1 0 Immediate early response protein (IER) CRAL_TRIO PF00650.15 EAK89136.1 - 8.8e-28 96.7 0.3 2.1e-27 95.5 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EAK89136.1 - 2.4e-05 24.2 1.0 2.4e-05 24.2 0.7 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Zip PF02535.17 EAK89136.1 - 3.6 6.5 12.8 6.4 5.6 8.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Telomere_Sde2 PF13019.1 EAK89137.1 - 5.4e-05 22.9 4.7 7.6e-05 22.4 3.2 1.4 1 1 0 1 1 1 1 Telomere stability and silencing FAST_1 PF06743.10 EAK89138.1 - 0.12 12.0 7.1 4.2 7.1 0.0 4.6 4 1 2 6 6 6 0 FAST kinase-like protein, subdomain 1 tRNA_anti-codon PF01336.20 EAK89139.1 - 0.0019 17.9 0.2 0.0045 16.8 0.2 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain PP2C PF00481.16 EAK89140.1 - 1.9e-19 70.0 0.0 1.9e-12 47.1 0.0 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EAK89140.1 - 0.00055 19.4 0.0 0.018 14.4 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C Mob_Pre PF01076.14 EAK89140.1 - 0.025 14.2 0.3 0.025 14.2 0.2 1.8 2 0 0 2 2 2 0 Plasmid recombination enzyme GAF_3 PF13492.1 EAK89141.1 - 1.5e-13 50.9 0.0 1.7e-10 41.0 0.0 3.2 3 0 0 3 3 3 1 GAF domain GAF_2 PF13185.1 EAK89141.1 - 0.014 15.8 0.0 14 6.1 0.0 3.1 3 0 0 3 3 3 0 GAF domain DUF566 PF04484.7 EAK89141.1 - 0.34 10.3 3.0 0.54 9.7 2.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DSPc PF00782.15 EAK89142.1 - 3.6e-27 94.5 0.0 1.7e-26 92.3 0.0 2.0 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAK89142.1 - 0.00076 18.8 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TRADD_N PF09034.5 EAK89142.1 - 0.033 14.1 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 TRADD, N-terminal domain zf-U1 PF06220.7 EAK89143.1 - 0.00031 20.2 1.3 0.0007 19.1 0.9 1.7 1 0 0 1 1 1 1 U1 zinc finger DUF3906 PF13046.1 EAK89143.1 - 0.055 13.1 1.5 0.16 11.6 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) LZ_Tnp_IS66 PF13007.2 EAK89144.1 - 2.2 9.0 9.6 61 4.3 4.0 4.0 2 1 0 2 2 2 0 Transposase C of IS166 homeodomain PFK PF00365.15 EAK89146.1 - 1.3e-34 119.4 3.2 3.7e-28 98.2 0.6 2.6 3 0 0 3 3 3 2 Phosphofructokinase IQ PF00612.22 EAK89148.1 - 3.2e-09 35.6 9.1 0.0004 19.7 0.6 4.4 4 0 0 4 4 4 2 IQ calmodulin-binding motif Urease_beta PF00699.15 EAK89148.1 - 0.12 12.2 0.2 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 Urease beta subunit IQ PF00612.22 EAK89149.1 - 0.0001 21.6 7.0 1.4 8.7 1.1 3.5 3 0 0 3 3 3 3 IQ calmodulin-binding motif ubiquitin PF00240.18 EAK89150.1 - 3.5e-12 45.5 0.0 6.8e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EAK89150.1 - 2.7e-06 26.9 0.1 5.8e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like NMD3 PF04981.8 EAK89151.1 - 9.8e-73 244.1 10.8 1.9e-72 243.1 7.5 1.5 1 0 0 1 1 1 1 NMD3 family UBA_4 PF14555.1 EAK89154.1 - 7e-15 54.2 0.7 1.5e-14 53.2 0.5 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EAK89154.1 - 2.8e-07 30.5 0.0 6.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 UBX domain Ubiquitin_3 PF14836.1 EAK89154.1 - 0.0027 17.3 0.6 0.25 11.0 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin-like domain TAP_C PF03943.8 EAK89154.1 - 0.1 12.0 0.7 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 TAP C-terminal domain Coiled-coil_56 PF09813.4 EAK89154.1 - 5.7 7.0 9.4 0.35 10.8 1.9 2.3 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 56 zf-C3HC4_3 PF13920.1 EAK89155.1 - 1.2e-14 53.6 10.6 2.5e-14 52.6 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK89155.1 - 4.3e-07 29.8 14.7 4.3e-07 29.8 10.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAK89155.1 - 0.00022 21.0 13.5 0.00034 20.3 8.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EAK89155.1 - 0.0013 18.3 13.2 0.0042 16.7 9.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain CABIT PF12736.2 EAK89155.1 - 0.044 12.7 1.0 0.06 12.3 0.5 1.3 1 1 0 1 1 1 0 Cell-cycle sustaining, positive selection, zf-P11 PF03854.9 EAK89155.1 - 0.39 10.2 12.7 1.5 8.3 8.8 2.0 1 1 0 1 1 1 0 P-11 zinc finger WhiA_N PF10298.4 EAK89157.1 - 0.033 14.0 0.0 0.082 12.7 0.0 1.7 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain HABP4_PAI-RBP1 PF04774.10 EAK89159.1 - 4.3e-06 27.1 8.1 4.3e-06 27.1 5.6 3.2 2 2 2 4 4 4 1 Hyaluronan / mRNA binding family DUF4200 PF13863.1 EAK89159.1 - 0.045 13.7 5.7 0.11 12.4 4.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) zf-CCCH_2 PF14608.1 EAK89160.1 - 2.9e-08 33.3 30.0 6e-05 22.8 4.4 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type PWI PF01480.12 EAK89160.1 - 4e-06 26.8 0.1 7.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 PWI domain DUF21 PF01595.15 EAK89161.1 - 1.6e-38 131.8 5.3 2.4e-38 131.2 3.6 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 Resolvase PF00239.16 EAK89161.1 - 0.044 13.6 0.5 7.9 6.3 0.0 2.5 2 1 1 3 3 3 0 Resolvase, N terminal domain Ribosomal_S6 PF01250.12 EAK89162.1 - 0.0096 15.7 1.2 0.058 13.2 0.3 2.4 2 0 0 2 2 2 1 Ribosomal protein S6 DUF421 PF04239.7 EAK89163.1 - 0.1 12.1 1.3 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF421) DUF2451 PF10474.4 EAK89165.1 - 0.0011 18.7 1.2 0.0015 18.3 0.7 1.4 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF3132 PF11330.3 EAK89165.1 - 0.045 13.5 0.1 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3132) TMF_DNA_bd PF12329.3 EAK89165.1 - 1.8 8.3 12.6 61 3.5 0.0 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GnsAB PF08178.6 EAK89165.1 - 6.3 6.5 9.7 1.9 8.2 1.6 3.1 3 0 0 3 3 3 0 GnsA/GnsB family CAP_N PF01213.14 EAK89167.1 - 0.023 13.9 0.1 0.028 13.7 0.1 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CM1 PF03026.10 EAK89167.1 - 0.043 12.9 0.0 0.055 12.5 0.0 1.1 1 0 0 1 1 1 0 Influenza C virus M1 protein Syntaxin_2 PF14523.1 EAK89167.1 - 0.056 13.4 1.1 0.082 12.9 0.7 1.4 1 1 0 1 1 1 0 Syntaxin-like protein BLOC1_2 PF10046.4 EAK89167.1 - 0.068 13.3 4.1 0.09 12.9 2.9 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-met PF12874.2 EAK89168.1 - 7.7e-06 25.9 1.8 2e-05 24.6 1.2 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EAK89168.1 - 1.4e-05 25.0 0.4 3.3e-05 23.8 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.7 EAK89168.1 - 0.014 15.0 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 DBF zinc finger AKAP95 PF04988.7 EAK89168.1 - 0.02 14.6 1.3 0.041 13.6 0.9 1.5 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 EAK89168.1 - 0.041 13.9 0.5 0.088 12.9 0.2 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ub-RnfH PF03658.9 EAK89168.1 - 0.048 13.5 0.4 0.21 11.4 0.3 2.0 1 1 0 1 1 1 0 RnfH family Ubiquitin DUF3633 PF12315.3 EAK89168.1 - 0.054 12.7 0.3 0.054 12.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3633) zf-C2H2 PF00096.21 EAK89168.1 - 0.18 12.2 0.5 0.4 11.1 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAK89168.1 - 0.23 11.9 0.9 0.47 10.9 0.7 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Vps39_2 PF10367.4 EAK89169.1 - 8.1e-20 71.0 0.4 2.9e-19 69.2 0.3 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF616 PF04765.8 EAK89170.1 - 0.006 15.7 2.2 0.0069 15.5 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF616) DUF1340 PF07067.6 EAK89170.1 - 0.026 13.7 1.3 0.029 13.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) TPR_2 PF07719.12 EAK89171.1 - 0.00039 20.1 0.1 15 5.8 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EAK89171.1 - 0.00047 19.3 0.1 0.0031 16.7 0.1 2.4 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 EAK89171.1 - 0.0022 17.5 0.7 1.6 8.3 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.1 EAK89171.1 - 0.0026 17.6 0.1 0.036 13.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat SPX PF03105.14 EAK89171.1 - 0.014 15.1 11.5 0.029 14.1 8.0 1.6 1 0 0 1 1 1 0 SPX domain DUF2217 PF10265.4 EAK89171.1 - 0.13 11.0 12.4 0.25 10.0 8.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Apt1 PF10351.4 EAK89171.1 - 0.44 9.3 18.3 1.1 7.9 12.7 1.6 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.1 EAK89171.1 - 0.93 9.2 20.3 2.1 8.0 14.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF515 PF04415.7 EAK89171.1 - 1.3 7.1 18.4 2.6 6.1 12.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CDK2AP PF09806.4 EAK89171.1 - 1.8 8.7 13.9 3.4 7.8 9.6 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein TPR_8 PF13181.1 EAK89171.1 - 5.6 6.9 13.0 0.2 11.5 0.2 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Spore_YhcN_YlaJ PF09580.5 EAK89173.1 - 0.064 13.3 2.7 0.09 12.8 1.9 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF1149 PF06619.6 EAK89173.1 - 0.098 12.5 6.4 0.17 11.8 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1149) DUF1191 PF06697.7 EAK89174.1 - 0.0017 17.2 0.0 0.0021 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Renin_r PF07850.9 EAK89174.1 - 0.027 14.8 0.1 0.041 14.2 0.1 1.4 1 1 0 1 1 1 0 Renin receptor-like protein DUF1032 PF06278.6 EAK89176.1 - 4.5e-29 101.3 10.8 3.3e-13 49.0 1.4 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1032) ScpA_ScpB PF02616.9 EAK89176.1 - 0.014 14.9 0.5 0.014 14.9 0.3 2.6 2 1 0 2 2 2 0 ScpA/B protein IGR PF09597.5 EAK89177.1 - 0.084 12.7 0.3 0.39 10.6 0.1 2.1 2 0 0 2 2 2 0 IGR protein motif CAML PF14963.1 EAK89178.1 - 9.5 5.4 14.0 0.057 12.7 3.4 1.9 3 1 0 3 3 3 0 Calcium signal-modulating cyclophilin ligand Rad60-SLD PF11976.3 EAK89179.1 - 8.6e-08 31.7 0.5 2.9e-07 30.0 0.4 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SWIB PF02201.13 EAK89182.1 - 3.5e-11 42.6 0.1 6.8e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Ribosomal_L29 PF00831.18 EAK89183.1 - 8.9e-19 66.9 2.4 8.9e-19 66.9 1.6 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein DUF1192 PF06698.6 EAK89183.1 - 0.026 14.3 2.4 0.073 12.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Ribosomal_S9 PF00380.14 EAK89183.1 - 0.11 12.7 4.2 0.14 12.4 2.4 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 Snapin_Pallidin PF14712.1 EAK89183.1 - 0.48 10.7 4.8 0.31 11.3 0.4 2.2 1 1 1 2 2 2 0 Snapin/Pallidin TrbL PF04610.9 EAK89184.1 - 0.00021 21.0 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein Prominin PF05478.6 EAK89184.1 - 0.00075 17.1 0.5 0.00075 17.1 0.3 1.2 1 0 0 1 1 1 1 Prominin Podoplanin PF05808.6 EAK89184.1 - 0.0098 15.4 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Podoplanin Rifin_STEVOR PF02009.11 EAK89184.1 - 0.011 15.4 0.6 0.013 15.1 0.4 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF799 PF05643.6 EAK89184.1 - 0.017 14.4 1.0 0.02 14.2 0.7 1.1 1 0 0 1 1 1 0 Putative bacterial lipoprotein (DUF799) Phage_Coat_Gp8 PF05371.7 EAK89184.1 - 0.032 13.8 0.2 0.055 13.0 0.2 1.4 1 0 0 1 1 1 0 Phage major coat protein, Gp8 DUF4064 PF13273.1 EAK89184.1 - 0.039 14.0 1.5 0.068 13.2 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Nucleos_tra2_C PF07662.8 EAK89184.1 - 0.046 13.2 0.2 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus TraG_N PF07916.6 EAK89184.1 - 0.051 12.0 0.0 0.058 11.8 0.0 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region CAAD PF14159.1 EAK89184.1 - 0.052 13.1 0.3 0.086 12.4 0.2 1.3 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase ETRAMP PF09716.5 EAK89184.1 - 0.061 13.2 0.1 0.13 12.2 0.1 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) ZYG-11_interact PF05884.7 EAK89184.1 - 0.25 10.3 2.3 0.15 11.1 0.2 1.7 2 1 0 2 2 2 0 Interactor of ZYG-11 AJAP1_PANP_C PF15298.1 EAK89184.1 - 0.51 10.1 5.2 0.7 9.7 3.6 1.3 1 1 0 1 1 1 0 AJAP1/PANP C-terminus DAG1 PF05454.6 EAK89184.1 - 1.4 8.0 8.9 2.8 7.0 6.1 1.7 1 1 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Shisa PF13908.1 EAK89184.1 - 2.8 8.0 14.0 8.9 6.4 9.7 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2668 PF10873.3 EAK89184.1 - 7.7 6.6 11.9 0.82 9.8 5.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) UPF0086 PF01868.11 EAK89186.1 - 1.7e-22 78.8 0.4 6.1e-22 77.0 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function UPF0086 Peptidase_C48 PF02902.14 EAK89188.1 - 4.2e-20 72.2 7.3 1.1e-19 70.9 3.0 2.6 1 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF3053 PF11254.3 EAK89189.1 - 0.0029 16.9 1.2 0.0036 16.5 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3053) TMCO5 PF14992.1 EAK89189.1 - 0.014 14.5 2.7 0.016 14.3 1.9 1.1 1 0 0 1 1 1 0 TMCO5 family Reo_sigmaC PF04582.7 EAK89189.1 - 0.017 14.3 2.2 0.024 13.8 1.5 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein RasGEF_N_2 PF14663.1 EAK89189.1 - 0.027 14.4 0.4 0.05 13.5 0.3 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Laminin_II PF06009.7 EAK89189.1 - 0.027 14.2 1.8 0.039 13.7 1.2 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF972 PF06156.8 EAK89189.1 - 0.21 11.9 5.2 0.096 13.0 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2935 PF11155.3 EAK89189.1 - 0.23 11.5 1.5 0.34 10.9 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) IncA PF04156.9 EAK89189.1 - 0.97 8.9 8.7 1.4 8.4 6.0 1.1 1 0 0 1 1 1 0 IncA protein SHNi-TPR PF10516.4 EAK89190.1 - 0.14 11.4 0.3 0.25 10.6 0.2 1.4 1 0 0 1 1 1 0 SHNi-TPR Abhydrolase_5 PF12695.2 EAK89191.1 - 1.3e-23 83.3 0.0 2.2e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAK89191.1 - 8.3e-15 55.2 0.0 1.9e-13 50.8 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EAK89191.1 - 7.6e-10 37.7 0.1 0.011 14.2 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 EAK89191.1 - 5.1e-06 26.2 0.1 0.0012 18.4 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAK89191.1 - 0.00023 20.4 0.0 0.0029 16.8 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF1057 PF06342.7 EAK89191.1 - 0.00026 19.9 0.0 0.00049 18.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) FSH1 PF03959.8 EAK89191.1 - 0.0005 19.5 0.1 0.0059 16.0 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 EAK89191.1 - 0.00052 19.7 0.0 0.77 9.4 0.0 2.3 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 EAK89191.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EAK89191.1 - 0.0031 16.8 0.0 0.083 12.1 0.0 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EAK89191.1 - 0.017 14.5 0.1 1.7 8.0 0.0 3.0 2 1 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2305 PF10230.4 EAK89191.1 - 0.023 14.1 0.0 0.078 12.3 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EAK89191.1 - 0.04 13.5 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 EAK89191.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EAK89191.1 - 0.071 12.6 1.1 0.47 9.9 0.4 2.5 2 1 0 2 2 2 0 PGAP1-like protein UPF0236 PF06782.6 EAK89192.1 - 0.56 8.5 0.0 1.1 7.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0236) ABC_tran PF00005.22 EAK89194.1 - 3.6e-20 72.6 0.4 1.7e-17 64.0 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 EAK89194.1 - 6.5e-06 25.7 47.5 0.0045 16.4 17.1 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.1 EAK89194.1 - 0.057 12.9 0.3 0.16 11.5 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AMP-binding PF00501.23 EAK89199.1 - 8.5e-64 215.4 0.0 1.1e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Pex14_N PF04695.8 EAK89200.1 - 2.6 8.0 5.3 4.1 7.4 2.7 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Jacalin PF01419.12 EAK89201.1 - 0.0023 17.8 2.2 0.14 12.0 0.1 3.8 4 0 0 4 4 4 1 Jacalin-like lectin domain PH_3 PF14593.1 EAK89201.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF900 PF05990.7 EAK89202.1 - 4.5e-24 85.0 0.0 9.5e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) KaiC PF06745.8 EAK89203.1 - 2.2e-05 23.6 1.0 7.7e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 KaiC UPF0239 PF06783.6 EAK89204.1 - 0.056 13.3 0.2 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) MFS_1 PF07690.11 EAK89206.1 - 6e-13 48.2 38.8 5.5e-10 38.4 15.2 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EAK89207.1 - 2.1e-05 23.4 37.3 2.1e-05 23.4 25.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily PAN_1 PF00024.21 EAK89209.1 - 2.7e-10 39.8 11.3 0.00012 21.7 3.2 3.4 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.1 EAK89209.1 - 3.8e-08 32.8 9.0 7.7e-06 25.5 0.9 3.6 3 0 0 3 3 3 2 PAN domain TPT PF03151.11 EAK89210.1 - 1.6e-14 53.8 10.3 1.6e-14 53.8 7.1 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EAK89210.1 - 2.8e-05 24.1 5.0 2.8e-05 24.1 3.5 2.8 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.11 EAK89211.1 - 8e-07 28.8 8.3 8e-07 28.8 5.8 2.7 2 1 1 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 EAK89211.1 - 4.6e-05 22.4 19.3 0.00013 21.0 13.4 1.9 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EAK89211.1 - 0.0022 18.1 1.0 0.0022 18.1 0.7 3.2 3 0 0 3 3 3 2 Multidrug resistance efflux transporter UPF0546 PF10639.4 EAK89211.1 - 0.0054 16.5 0.5 0.0054 16.5 0.4 2.7 4 0 0 4 4 4 1 Uncharacterised protein family UPF0546 Rab5ip PF07019.7 EAK89211.1 - 0.68 10.1 7.3 0.25 11.5 0.3 3.4 2 2 1 3 3 3 0 Rab5-interacting protein (Rab5ip) EamA PF00892.15 EAK89211.1 - 1.1 9.3 26.8 0.057 13.4 4.2 3.2 3 1 1 4 4 4 0 EamA-like transporter family TPT PF03151.11 EAK89212.1 - 4.2e-12 45.9 8.3 4.2e-12 45.9 5.8 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EAK89212.1 - 0.00045 20.2 7.6 0.00045 20.2 5.3 3.0 1 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EAK89212.1 - 0.21 11.7 25.0 0.48 10.6 4.6 3.2 3 0 0 3 3 3 0 Multidrug resistance efflux transporter YrvL PF14184.1 EAK89214.1 - 0.11 12.3 3.1 0.85 9.4 0.2 2.1 2 0 0 2 2 2 0 Regulatory protein YrvL Aa_trans PF01490.13 EAK89215.1 - 2.5e-21 75.6 31.2 2.5e-17 62.4 10.2 2.5 2 1 1 3 3 3 2 Transmembrane amino acid transporter protein DUF912 PF06024.7 EAK89215.1 - 0.0096 15.9 2.2 0.045 13.7 0.1 2.9 3 0 0 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) GSHPx PF00255.14 EAK89216.1 - 7.4e-26 89.6 0.0 1.4e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EAK89216.1 - 4.2e-08 32.9 0.0 1.4e-06 28.0 0.0 2.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EAK89216.1 - 0.00011 21.7 0.0 0.00042 19.8 0.0 1.8 1 1 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 EAK89216.1 - 0.0043 16.6 0.1 0.042 13.4 0.0 2.2 1 1 0 1 1 1 1 SCO1/SenC mRNA_triPase PF02940.10 EAK89217.1 - 8.4e-15 55.0 2.1 1.3e-14 54.4 1.5 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain LRRC37AB_C PF14914.1 EAK89218.1 - 0.0015 18.0 0.1 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain LST1 PF05083.8 EAK89218.1 - 0.029 14.3 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 LST-1 protein EphA2_TM PF14575.1 EAK89218.1 - 0.037 14.4 0.1 0.037 14.4 0.1 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MLANA PF14991.1 EAK89218.1 - 0.072 13.1 1.3 0.23 11.5 0.0 2.4 2 0 0 2 2 2 0 Protein melan-A Vfa1 PF08432.5 EAK89218.1 - 0.15 12.0 11.8 0.041 13.9 3.3 2.9 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 TMEM154 PF15102.1 EAK89218.1 - 0.37 10.5 0.0 0.37 10.5 0.0 3.0 2 1 0 2 2 1 0 TMEM154 protein family DUF912 PF06024.7 EAK89218.1 - 0.39 10.7 0.1 0.39 10.7 0.0 3.2 2 2 0 2 2 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Med3 PF11593.3 EAK89218.1 - 0.39 9.8 24.7 0.67 9.1 17.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2407_C PF13373.1 EAK89218.1 - 0.41 10.5 4.4 0.25 11.2 0.2 2.8 2 1 2 4 4 4 0 DUF2407 C-terminal domain Glycophorin_A PF01102.13 EAK89218.1 - 0.41 10.4 0.0 0.41 10.4 0.0 3.5 2 1 0 2 2 1 0 Glycophorin A Pneumo_att_G PF05539.6 EAK89218.1 - 0.75 9.1 30.1 1.2 8.4 20.9 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Chorein_N PF12624.2 EAK89219.1 - 1e-28 99.2 0.1 8.9e-28 96.1 0.1 2.7 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EAK89219.1 - 2.5e-06 27.5 0.2 1.8e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 ATG C terminal domain WWE PF02825.15 EAK89220.1 - 0.093 12.1 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 WWE domain ABC_tran PF00005.22 EAK89221.1 - 1e-24 87.3 0.0 1e-11 45.2 0.0 3.0 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAK89221.1 - 3.9e-24 85.5 40.3 2.1e-15 56.9 13.2 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_29 PF13555.1 EAK89221.1 - 7.1e-07 28.6 0.4 0.0029 17.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EAK89221.1 - 1.1e-06 27.7 0.0 0.025 13.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 EAK89221.1 - 4.6e-06 27.4 4.4 0.019 15.7 0.0 4.1 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EAK89221.1 - 9.7e-06 25.1 0.0 0.005 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EAK89221.1 - 2.3e-05 24.8 0.1 0.41 11.1 0.0 3.7 2 1 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 EAK89221.1 - 3.2e-05 23.5 1.4 0.071 12.5 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EAK89221.1 - 4.4e-05 23.4 0.7 0.17 11.8 0.6 3.4 2 1 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EAK89221.1 - 0.0004 19.6 0.8 0.25 10.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EAK89221.1 - 0.0009 19.5 0.6 0.72 10.1 0.0 3.9 4 0 0 4 4 3 1 AAA domain MobB PF03205.9 EAK89221.1 - 0.0012 18.5 1.3 1.3 8.7 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EAK89221.1 - 0.0017 18.3 0.5 0.47 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.18 EAK89221.1 - 0.0017 18.1 2.9 0.18 11.5 0.2 2.9 2 0 0 2 2 2 1 Dynamin family NACHT PF05729.7 EAK89221.1 - 0.0018 17.9 0.8 1.9 8.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 EAK89221.1 - 0.002 18.2 2.7 1.8 8.6 0.1 3.1 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EAK89221.1 - 0.0078 16.0 0.0 5.5 6.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EAK89221.1 - 0.0094 15.4 4.3 1 8.7 0.1 2.8 3 0 0 3 3 3 2 AAA-like domain IstB_IS21 PF01695.12 EAK89221.1 - 0.016 14.6 0.0 2.2 7.6 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein cobW PF02492.14 EAK89221.1 - 0.042 13.2 3.1 1.8 8.0 0.3 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EAK89221.1 - 0.087 12.3 0.0 6.4 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EAK89221.1 - 2.6 7.8 15.2 0.77 9.5 0.3 3.7 3 1 0 4 4 4 0 Domain of unknown function DUF87 DEAD PF00270.24 EAK89223.1 - 9.5e-19 67.5 0.0 1.7e-17 63.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK89223.1 - 1.4e-16 60.1 0.0 4.5e-16 58.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CpeS PF09367.5 EAK89225.1 - 0.032 14.1 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 CpeS-like protein CAF1 PF04857.15 EAK89226.1 - 2.2e-58 197.6 2.0 3.2e-58 197.1 1.4 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease RNase_T PF00929.19 EAK89226.1 - 0.12 12.7 0.0 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 Exonuclease Sdh_cyt PF01127.17 EAK89227.1 - 0.12 12.1 9.1 0.028 14.2 1.6 2.6 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Lig_chan PF00060.21 EAK89227.1 - 0.63 9.7 6.6 3.3 7.4 0.3 2.4 2 0 0 2 2 2 0 Ligand-gated ion channel RCC1 PF00415.13 EAK89228.1 - 2.2e-111 363.9 36.4 4.2e-14 52.4 0.3 13.8 13 1 0 13 13 13 11 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EAK89228.1 - 2e-52 173.7 70.7 2.2e-08 33.4 0.2 13.4 13 0 0 13 13 13 12 Regulator of chromosome condensation (RCC1) repeat Hexokinase_2 PF03727.11 EAK89228.1 - 0.054 12.6 0.4 0.099 11.8 0.3 1.3 1 0 0 1 1 1 0 Hexokinase NTF2 PF02136.15 EAK89229.1 - 2.5e-11 44.0 0.2 9.3e-11 42.1 0.0 2.0 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Mucin PF01456.12 EAK89229.1 - 0.076 12.7 13.8 0.019 14.7 6.1 2.2 2 1 0 2 2 2 0 Mucin-like glycoprotein GTP_EFTU PF00009.22 EAK89230.1 - 2.9e-39 134.4 0.1 4.8e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EAK89230.1 - 2.7e-33 113.8 0.0 5.7e-33 112.8 0.0 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EAK89230.1 - 1.7e-10 40.8 0.4 1.7e-10 40.8 0.3 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 Dak1_2 PF13684.1 EAK89230.1 - 0.008 15.1 0.4 0.013 14.4 0.3 1.2 1 0 0 1 1 1 1 Dihydroxyacetone kinase family MMR_HSR1 PF01926.18 EAK89230.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Metallophos PF00149.23 EAK89231.1 - 5e-09 35.8 3.8 1.8e-08 34.0 0.1 2.4 1 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAK89231.1 - 0.00071 19.4 0.0 0.0016 18.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DBR1 PF05011.8 EAK89231.1 - 0.0021 17.9 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Peptidase_M16 PF00675.15 EAK89232.1 - 3e-27 95.2 1.6 1.1e-26 93.3 0.2 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAK89232.1 - 6.8e-14 51.9 0.5 7e-08 32.3 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Prp19_bind PF06991.6 EAK89232.1 - 0.3 10.3 0.7 0.53 9.5 0.5 1.3 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Peptidase_M16 PF00675.15 EAK89233.1 - 2.8e-12 46.6 0.0 2.8e-12 46.6 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAK89233.1 - 2.1e-08 34.0 0.2 2.1e-08 34.0 0.1 2.6 3 0 0 3 3 3 1 Peptidase M16 inactive domain TFIIF_alpha PF05793.7 EAK89233.1 - 0.49 8.6 18.0 0.76 8.0 12.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cyclin_N PF00134.18 EAK89234.1 - 2.1e-29 101.6 0.7 6.4e-29 100.0 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EAK89234.1 - 0.00068 19.5 0.1 0.0022 17.9 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Thioredoxin_7 PF13899.1 EAK89235.1 - 5.6e-08 32.6 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 EAK89235.1 - 1.6e-07 30.7 0.1 4.1e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain Sugar_tr PF00083.19 EAK89236.1 - 1.3e-48 165.7 24.7 1.6e-48 165.4 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAK89236.1 - 3.8e-31 108.0 43.5 7.7e-25 87.3 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Bax1-I PF01027.15 EAK89237.1 - 4.8e-25 88.3 40.6 5.6e-25 88.1 28.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PCI_Csn8 PF10075.4 EAK89238.1 - 2.3e-30 105.2 0.8 4.6e-30 104.2 0.1 1.7 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EAK89238.1 - 7.9e-16 58.2 3.1 1e-15 57.8 2.2 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DmpG_comm PF07836.6 EAK89238.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 DmpG-like communication domain Ribosomal_L18e PF00828.14 EAK89239.1 - 3.8e-31 108.1 0.2 3.8e-31 108.1 0.1 1.3 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Ribosomal_L7Ae PF01248.21 EAK89240.1 - 8.7e-24 82.8 0.0 9.9e-24 82.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DPBB_1 PF03330.13 EAK89240.1 - 0.016 15.1 0.3 0.83 9.7 0.0 2.1 1 1 0 2 2 2 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Nuf2 PF03800.9 EAK89242.1 - 1.5e-35 122.3 0.0 1.5e-35 122.3 0.0 2.7 2 1 0 3 3 3 1 Nuf2 family DUF2379 PF09543.5 EAK89242.1 - 0.011 15.7 0.7 0.011 15.7 0.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2379) Filament PF00038.16 EAK89242.1 - 0.079 12.4 54.3 0.045 13.2 8.7 3.8 1 1 0 2 2 2 0 Intermediate filament protein Synaptonemal_3 PF15191.1 EAK89242.1 - 4.4 7.1 13.8 3.6 7.3 0.8 4.0 2 1 0 3 3 3 0 Synaptonemal complex central element protein 3 Reo_sigmaC PF04582.7 EAK89242.1 - 8.2 5.5 13.4 0.15 11.2 1.1 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DKCLD PF08068.7 EAK89243.1 - 5e-29 99.9 0.1 1.8e-28 98.2 0.0 2.0 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_N PF01509.13 EAK89243.1 - 3.2e-23 82.5 0.1 6.2e-20 71.8 0.0 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EAK89243.1 - 1e-19 70.0 2.9 2.4e-19 68.8 2.0 1.7 1 0 0 1 1 1 1 PUA domain SR-25 PF10500.4 EAK89243.1 - 0.017 14.6 49.5 0.025 14.0 34.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Clat_adaptor_s PF01217.15 EAK89244.1 - 3e-20 72.3 3.3 3.6e-20 72.1 2.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1827 PF08860.5 EAK89244.1 - 0.0075 16.3 0.0 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1827) AP-5_subunit_s1 PF15001.1 EAK89244.1 - 0.019 14.9 0.1 0.87 9.4 0.0 2.1 1 1 1 2 2 2 0 AP-5 complex subunit sigma-1 DUF682 PF05081.7 EAK89244.1 - 0.063 12.8 0.3 0.12 11.8 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF682) Ribosomal_L19e PF01280.15 EAK89245.1 - 4.7e-55 185.4 12.2 6.5e-55 184.9 8.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L19e HSP90 PF00183.13 EAK89246.1 - 2.6e-250 831.3 29.8 3.7e-250 830.8 20.6 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EAK89246.1 - 1.8e-12 46.9 0.2 3.2e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EAK89246.1 - 9e-12 44.8 0.4 9e-12 44.8 0.3 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EF-hand_1 PF00036.27 EAK89247.1 - 4.2e-05 22.5 0.3 0.052 12.8 0.0 3.5 3 1 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EAK89247.1 - 0.0011 19.0 0.0 0.007 16.4 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EAK89247.1 - 0.012 15.4 2.1 0.42 10.6 0.0 3.4 4 1 1 5 5 5 0 EF-hand domain EF-hand_9 PF14658.1 EAK89247.1 - 0.06 13.2 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain MBF1 PF08523.5 EAK89248.1 - 2e-23 82.1 0.9 2e-23 82.1 0.6 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EAK89248.1 - 5.4e-13 48.5 0.1 1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EAK89248.1 - 7.6e-08 32.2 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EAK89248.1 - 4.7e-06 26.7 0.0 7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 EAK89248.1 - 0.0062 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain BCNT PF07572.7 EAK89248.1 - 0.11 12.4 0.4 0.22 11.4 0.3 1.5 1 0 0 1 1 1 0 Bucentaur or craniofacial development DUF4205 PF13898.1 EAK89249.1 - 4.8e-44 150.5 1.1 8.3e-44 149.7 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4205) EF-hand_6 PF13405.1 EAK89249.1 - 0.013 15.2 4.1 0.2 11.6 0.4 3.9 3 0 0 3 3 3 0 EF-hand domain EF-hand_7 PF13499.1 EAK89249.1 - 0.03 14.4 0.3 0.03 14.4 0.2 3.2 4 0 0 4 4 4 0 EF-hand domain pair Tubulin_3 PF14881.1 EAK89249.1 - 0.045 13.2 0.2 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Tubulin domain BolA PF01722.13 EAK89250.1 - 2.4e-18 65.8 0.0 3e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein DUF1505 PF07403.6 EAK89250.1 - 0.028 14.3 0.8 0.033 14.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) RPAP1_N PF08621.5 EAK89250.1 - 0.11 12.1 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal Peptidase_M18 PF02127.10 EAK89251.1 - 4.2e-121 404.4 0.0 7.5e-121 403.6 0.0 1.4 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EAK89251.1 - 4.4e-10 38.7 0.0 7e-07 28.2 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Zip PF02535.17 EAK89252.1 - 0.52 9.2 0.0 0.52 9.2 0.0 2.8 3 0 0 3 3 3 0 ZIP Zinc transporter Glyco_transf_22 PF03901.12 EAK89253.1 - 3.4e-59 200.9 55.8 8e-59 199.6 38.7 1.6 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Rep_fac-A_3 PF08661.6 EAK89254.1 - 2.9e-24 85.0 0.1 3.8e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF2993 PF11209.3 EAK89254.1 - 0.074 12.9 0.1 0.087 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2993) DEAD PF00270.24 EAK89255.1 - 2e-28 99.0 0.0 3.4e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK89255.1 - 6.2e-14 51.6 0.0 2.8e-12 46.3 0.0 2.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAK89255.1 - 2e-07 31.0 0.2 4.8e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit tRNA-synt_2d PF01409.15 EAK89256.1 - 5.6e-85 284.4 0.0 7.6e-85 284.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EAK89256.1 - 3.2e-05 22.8 0.1 0.00054 18.8 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EAK89256.1 - 8.7e-05 22.1 0.1 0.00014 21.4 0.1 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) S10_plectin PF03501.10 EAK89256.1 - 0.0057 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 Plectin/S10 domain DNA_pol3_delta2 PF13177.1 EAK89257.1 - 2.2e-14 53.4 0.5 4.1e-14 52.5 0.3 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EAK89257.1 - 6.4e-14 52.2 0.1 2.1e-13 50.6 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EAK89257.1 - 8.4e-13 48.1 0.0 2.8e-12 46.4 0.0 2.0 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EAK89257.1 - 3e-10 39.4 0.5 5.1e-09 35.3 0.0 2.1 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EAK89257.1 - 2.1e-07 31.1 0.0 1.2e-06 28.6 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EAK89257.1 - 5e-07 29.5 0.0 7.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAK89257.1 - 1.1e-06 28.4 2.2 0.004 16.7 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 EAK89257.1 - 1.5e-05 25.1 0.0 3.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EAK89257.1 - 0.00025 20.1 0.1 0.00079 18.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EAK89257.1 - 0.00028 20.6 0.1 0.0045 16.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.24 EAK89257.1 - 0.00042 19.8 0.2 0.003 17.0 0.1 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 EAK89257.1 - 0.00045 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain PIF1 PF05970.9 EAK89257.1 - 0.0011 17.9 0.6 0.0076 15.2 0.4 1.9 1 1 0 1 1 1 1 PIF1-like helicase DUF815 PF05673.8 EAK89257.1 - 0.0013 17.6 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.8 EAK89257.1 - 0.0029 17.1 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 EAK89257.1 - 0.0038 16.8 0.1 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EAK89257.1 - 0.0043 16.0 0.0 0.0065 15.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EAK89257.1 - 0.0069 16.2 0.0 0.021 14.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_23 PF13476.1 EAK89257.1 - 0.01 16.1 1.5 0.017 15.4 1.1 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAK89257.1 - 0.013 15.7 0.5 1.2 9.4 0.0 3.0 2 1 1 3 3 3 0 ABC transporter Arch_ATPase PF01637.13 EAK89257.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 EAK89257.1 - 0.03 13.1 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 EAK89257.1 - 0.038 12.9 0.0 0.094 11.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 EAK89257.1 - 0.043 12.9 0.0 0.12 11.5 0.0 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI NYD-SP12_N PF15015.1 EAK89257.1 - 0.045 11.9 0.1 0.067 11.4 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Torsin PF06309.6 EAK89257.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.21 EAK89257.1 - 0.1 12.0 0.1 1.5 8.2 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.1 EAK89257.1 - 0.11 13.3 0.1 0.25 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAK89257.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAK89257.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PLDc_2 PF13091.1 EAK89258.1 - 4.8e-26 90.9 3.5 6.8e-13 48.4 0.2 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EAK89258.1 - 2.6e-05 23.8 0.4 0.0011 18.6 0.0 2.5 2 0 0 2 2 2 1 Phospholipase D Active site motif Chrome_Resist PF09828.4 EAK89258.1 - 0.038 14.1 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Chromate resistance exported protein LRR_9 PF14580.1 EAK89259.1 - 1.4e-26 93.0 1.3 1.4e-26 93.0 0.9 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EAK89259.1 - 3.5e-15 55.2 25.2 7.3e-10 38.2 4.0 4.9 5 1 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAK89259.1 - 1.1e-10 41.1 11.5 7.9e-10 38.3 3.1 4.2 1 1 3 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 EAK89259.1 - 3.2e-05 23.3 14.4 0.31 11.2 0.1 5.5 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 EAK89259.1 - 0.00056 19.7 12.2 0.22 11.6 0.1 5.7 4 2 0 4 4 4 1 Leucine Rich repeat LRR_7 PF13504.1 EAK89259.1 - 0.01 15.8 12.0 0.28 11.5 0.1 5.3 7 0 0 7 7 7 0 Leucine rich repeat NUFIP1 PF10453.4 EAK89260.1 - 0.00016 21.1 1.6 0.00064 19.1 0.1 2.8 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.3 EAK89260.1 - 0.041 14.0 4.2 0.066 13.3 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SPC22 PF04573.7 EAK89261.1 - 1.1e-26 93.0 2.9 1.4e-26 92.7 2.0 1.1 1 0 0 1 1 1 1 Signal peptidase subunit Runt PF00853.14 EAK89261.1 - 0.12 11.8 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 Runt domain RNA_pol_Rpb1_5 PF04998.12 EAK89262.1 - 1.4e-103 345.9 0.3 2.4e-103 345.2 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EAK89262.1 - 2.2e-97 326.3 0.2 4.9e-97 325.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EAK89262.1 - 2.5e-69 232.4 0.0 6.9e-69 231.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EAK89262.1 - 4.5e-53 179.7 0.1 8.6e-53 178.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EAK89262.1 - 6.7e-45 152.6 0.3 2.2e-44 150.9 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EAK89262.1 - 1.4e-40 138.1 3.6 3.1e-40 136.9 2.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EAK89262.1 - 2.3e-37 127.0 0.1 9e-37 125.1 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EAK89262.1 - 5.5e-09 35.4 304.3 0.014 15.4 8.2 21.7 12 4 8 23 23 23 17 RNA polymerase Rpb1 C-terminal repeat TFIIS_C PF01096.13 EAK89263.1 - 3.1e-14 52.3 7.7 3.1e-14 52.3 5.3 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF2072 PF09845.4 EAK89263.1 - 0.056 13.3 2.4 0.18 11.7 0.0 2.4 2 1 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) Zn_Tnp_IS1595 PF12760.2 EAK89263.1 - 0.072 12.9 10.8 0.82 9.5 2.5 2.9 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EAK89263.1 - 0.32 10.5 0.1 0.32 10.5 0.1 3.7 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Terminase_GpA PF05876.7 EAK89263.1 - 0.61 8.3 4.5 1.4 7.1 1.4 2.0 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) zf-CSL PF05207.8 EAK89263.1 - 0.86 9.1 7.0 8.2 6.0 0.0 3.3 3 1 0 3 3 3 0 CSL zinc finger Lar_restr_allev PF14354.1 EAK89263.1 - 1.2 9.5 6.4 10 6.5 1.5 2.6 2 1 1 3 3 3 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.7 EAK89263.1 - 1.9 7.8 10.3 6.5 6.1 0.1 3.9 4 0 0 4 4 4 0 TFIIB zinc-binding Myb_DNA-bind_6 PF13921.1 EAK89264.1 - 1.1e-10 41.4 0.5 1.1e-10 41.4 0.3 4.0 5 0 0 5 5 5 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAK89264.1 - 3.3e-10 39.8 1.8 3.5e-09 36.5 0.6 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EAK89264.1 - 0.36 10.7 7.7 5.3 6.9 0.1 4.0 5 0 0 5 5 5 0 Myb/SANT-like DNA-binding domain zf-CSL PF05207.8 EAK89265.1 - 3.1e-14 52.1 0.6 4.2e-14 51.7 0.4 1.2 1 0 0 1 1 1 1 CSL zinc finger Ribosomal_L37ae PF01780.14 EAK89266.1 - 9.7e-35 118.3 6.5 1.2e-34 118.0 4.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EAK89266.1 - 0.0001 22.0 4.9 0.00017 21.3 3.4 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EAK89266.1 - 0.0012 18.2 3.6 0.041 13.3 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-H2C2_2 PF13465.1 EAK89266.1 - 0.02 15.1 3.1 0.11 12.8 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain UPF0547 PF10571.4 EAK89266.1 - 0.053 13.2 1.1 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-BED PF02892.10 EAK89266.1 - 0.057 13.1 2.8 0.93 9.3 0.3 2.3 1 1 1 2 2 2 0 BED zinc finger zf-Sec23_Sec24 PF04810.10 EAK89266.1 - 0.06 12.9 0.6 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2 PF00096.21 EAK89266.1 - 0.078 13.3 2.2 1.1 9.7 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAK89266.1 - 0.11 12.8 1.6 1.6 9.2 0.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 EAK89266.1 - 0.13 12.3 0.4 0.22 11.6 0.3 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Lar_restr_allev PF14354.1 EAK89266.1 - 0.21 11.9 3.2 0.54 10.5 2.2 1.7 1 1 0 1 1 1 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 EAK89266.1 - 0.25 11.2 3.0 0.37 10.7 0.3 2.2 2 0 0 2 2 2 0 Zinc ribbon domain UMP1 PF05348.6 EAK89267.1 - 7.2e-12 45.3 0.1 9e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rep_fac-A_C PF08646.5 EAK89268.1 - 6.1e-22 77.8 4.2 1.3e-21 76.8 2.7 1.7 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 EAK89268.1 - 8.3e-08 31.9 0.4 2e-06 27.5 0.0 2.9 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain SSB PF00436.20 EAK89268.1 - 0.014 15.2 0.2 9.8 6.0 0.0 3.0 2 1 0 2 2 2 0 Single-strand binding protein family DZR PF12773.2 EAK89268.1 - 0.083 12.7 0.5 0.21 11.4 0.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon SprT-like PF10263.4 EAK89269.1 - 1.1e-38 132.3 1.0 1.4e-38 132.0 0.7 1.1 1 0 0 1 1 1 1 SprT-like family DUF3932 PF13068.1 EAK89269.1 - 0.038 14.0 0.1 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) Nop PF01798.13 EAK89270.1 - 4.6e-59 198.0 0.4 7.8e-59 197.2 0.3 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EAK89270.1 - 4.7e-26 90.3 0.0 9.2e-26 89.4 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EAK89270.1 - 9.7e-21 73.7 0.2 2.1e-20 72.6 0.1 1.6 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Ribosomal_S2 PF00318.15 EAK89271.1 - 1.4e-40 138.8 1.9 3.9e-20 71.9 0.2 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 Pox_A22 PF04848.8 EAK89271.1 - 0.066 13.0 0.3 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Poxvirus A22 protein zf-RING_2 PF13639.1 EAK89272.1 - 5.8e-13 48.4 5.8 5.8e-13 48.4 4.0 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_3 PF14369.1 EAK89272.1 - 6.2e-12 45.3 2.3 6.2e-12 45.3 1.6 2.4 2 0 0 2 2 2 1 zinc-finger zf-rbx1 PF12678.2 EAK89272.1 - 6.3e-08 32.6 4.6 6.3e-08 32.6 3.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EAK89272.1 - 3.4e-05 23.6 2.4 3.4e-05 23.6 1.6 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EAK89272.1 - 0.00016 21.2 4.7 0.00016 21.2 3.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK89272.1 - 0.00092 19.1 4.4 0.00092 19.1 3.1 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK89272.1 - 0.002 17.8 17.7 0.0037 16.9 3.4 2.7 2 1 0 2 2 2 2 zinc-RING finger domain Zn-ribbon_8 PF09723.5 EAK89272.1 - 0.0078 16.1 1.6 0.0078 16.1 1.1 2.3 2 0 0 2 2 2 1 Zinc ribbon domain FANCL_C PF11793.3 EAK89272.1 - 0.0083 16.0 3.9 0.0083 16.0 2.7 2.3 2 0 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 EAK89272.1 - 0.012 15.2 6.1 0.012 15.2 4.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EAK89272.1 - 0.28 10.6 2.9 0.51 9.8 0.0 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif DZR PF12773.2 EAK89272.1 - 0.83 9.5 13.2 0.17 11.6 2.4 2.8 2 1 0 2 2 2 0 Double zinc ribbon BIV_Env PF05858.7 EAK89272.1 - 0.97 7.3 3.7 1.4 6.7 2.6 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) HypA PF01155.14 EAK89272.1 - 8.2 6.1 9.7 0.55 9.9 1.4 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Choline_kinase PF01633.15 EAK89273.1 - 8.3e-52 175.8 3.7 1.2e-51 175.3 2.6 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EAK89273.1 - 1.7e-07 31.2 0.0 2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family PP2C PF00481.16 EAK89274.1 - 2.8e-63 213.6 0.1 4.7e-52 176.9 0.1 2.6 3 0 0 3 3 3 2 Protein phosphatase 2C BAG PF02179.11 EAK89274.1 - 0.05 13.7 0.4 0.76 9.9 0.0 2.5 2 0 0 2 2 2 0 BAG domain RRM_6 PF14259.1 EAK89275.1 - 1e-12 47.7 0.4 1.7e-06 27.8 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAK89275.1 - 8.3e-12 44.5 0.0 1.9e-07 30.6 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 EAK89275.1 - 0.0021 17.4 0.4 0.0057 16.0 0.3 1.8 1 0 0 1 1 1 1 Lsm interaction motif YjfB_motility PF14070.1 EAK89275.1 - 0.0062 16.3 2.1 1.5 8.6 0.0 2.9 2 0 0 2 2 2 2 Putative motility protein FdhE PF04216.7 EAK89275.1 - 0.083 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Sec23_trunk PF04811.10 EAK89276.1 - 9.2e-64 215.1 0.0 1.4e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EAK89276.1 - 5.8e-32 109.1 0.5 1.1e-31 108.2 0.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EAK89276.1 - 4.7e-31 107.1 0.3 1.9e-30 105.2 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EAK89276.1 - 1.2e-15 56.7 5.3 2.3e-15 55.8 3.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EAK89276.1 - 5.8e-13 48.3 0.2 6.9e-12 44.8 0.2 2.5 2 1 0 2 2 2 1 Gelsolin repeat VP_N-CPKC PF11475.3 EAK89276.1 - 0.041 13.4 0.4 0.095 12.2 0.3 1.5 1 0 0 1 1 1 0 Virion protein N terminal domain VWA_2 PF13519.1 EAK89276.1 - 0.16 12.1 0.0 0.43 10.6 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain DUF866 PF05907.8 EAK89277.1 - 3.7e-32 111.0 1.5 4.5e-32 110.7 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DEAD PF00270.24 EAK89278.1 - 6.9e-34 116.7 0.0 1.5e-33 115.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EAK89278.1 - 4.1e-23 80.6 0.5 9.1e-23 79.5 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EAK89278.1 - 7.6e-23 80.1 0.0 2.7e-22 78.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EAK89278.1 - 0.056 13.5 0.2 6.1 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Rep_fac_C PF08542.6 EAK89279.1 - 1e-16 60.6 0.0 3.4e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.24 EAK89279.1 - 1.3e-15 57.7 0.0 2.3e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EAK89279.1 - 2.5e-12 46.7 0.1 5.7e-10 39.0 0.1 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 EAK89279.1 - 1.1e-08 35.2 0.2 1.8e-06 28.0 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EAK89279.1 - 1.5e-07 31.3 0.0 3.4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EAK89279.1 - 4.1e-07 29.0 0.2 2.6e-05 23.1 0.0 2.2 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EAK89279.1 - 5.7e-07 28.8 0.1 1.4e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EAK89279.1 - 9e-06 25.8 0.6 0.0027 17.8 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAK89279.1 - 1.9e-05 24.2 0.0 4.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EAK89279.1 - 0.00011 21.9 0.3 0.00068 19.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EAK89279.1 - 0.00016 21.3 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EAK89279.1 - 0.0002 20.5 0.1 0.0037 16.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EAK89279.1 - 0.00028 20.6 0.9 0.19 11.4 0.0 2.3 1 1 1 2 2 2 2 NTPase AAA_10 PF12846.2 EAK89279.1 - 0.00033 20.2 0.5 0.26 10.6 0.0 2.3 1 1 1 2 2 2 2 AAA-like domain AAA_11 PF13086.1 EAK89279.1 - 0.00052 19.6 0.0 0.00077 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EAK89279.1 - 0.00059 19.8 0.1 0.0029 17.6 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain DNA_pol3_delta PF06144.8 EAK89279.1 - 0.0019 17.7 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_17 PF13207.1 EAK89279.1 - 0.0068 17.2 0.1 0.039 14.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAK89279.1 - 0.0068 16.7 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EAK89279.1 - 0.0079 16.3 0.1 0.038 14.1 0.1 2.1 1 1 0 1 1 1 1 RNA helicase ArgK PF03308.11 EAK89279.1 - 0.01 14.6 0.1 0.093 11.4 0.1 2.1 1 1 1 2 2 2 0 ArgK protein Viral_helicase1 PF01443.13 EAK89279.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 EAK89279.1 - 0.011 15.2 0.1 1 8.8 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase IstB_IS21 PF01695.12 EAK89279.1 - 0.012 15.0 0.1 0.044 13.2 0.1 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF2893 PF11459.3 EAK89279.1 - 0.016 14.9 0.2 0.26 11.1 0.0 2.8 3 0 0 3 3 2 0 Protein of unknwon function (DUF2893) AAA_28 PF13521.1 EAK89279.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EAK89279.1 - 0.018 14.5 1.0 0.084 12.3 0.1 2.4 2 2 1 3 3 3 0 FtsK/SpoIIIE family T2SE PF00437.15 EAK89279.1 - 0.022 13.6 0.1 0.12 11.2 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.1 EAK89279.1 - 0.029 13.7 0.3 0.34 10.2 0.1 2.5 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.5 EAK89279.1 - 0.042 13.0 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF815 PF05673.8 EAK89279.1 - 0.048 12.5 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KaiC PF06745.8 EAK89279.1 - 0.06 12.4 0.3 0.23 10.5 0.1 2.0 1 1 0 1 1 1 0 KaiC AAA_30 PF13604.1 EAK89279.1 - 0.07 12.7 0.1 0.22 11.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain SecA_DEAD PF07517.9 EAK89279.1 - 0.071 12.3 0.3 0.1 11.9 0.2 1.4 1 1 0 1 1 1 0 SecA DEAD-like domain AAA_29 PF13555.1 EAK89279.1 - 0.094 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EAK89279.1 - 0.096 12.5 0.1 0.18 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAK89279.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF1242 PF06842.7 EAK89280.1 - 1.5e-15 56.4 0.4 2e-15 55.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Ycf66_N PF07444.6 EAK89280.1 - 0.12 12.0 0.8 0.21 11.3 0.5 1.6 1 1 0 1 1 1 0 Ycf66 protein N-terminus Methyltransf_11 PF08241.7 EAK89281.1 - 5.1e-05 23.6 0.0 9.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAK89281.1 - 0.00064 19.3 0.1 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAK89281.1 - 0.0015 18.2 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAK89281.1 - 0.0053 17.1 0.0 0.0091 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain 14-3-3 PF00244.15 EAK89282.1 - 2.7e-108 360.4 4.6 3.2e-108 360.2 3.2 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EAK89282.1 - 0.013 15.4 1.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Acyl-CoA_dh_2 PF08028.6 EAK89282.1 - 0.016 15.4 0.6 0.092 12.9 0.1 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain TPR_14 PF13428.1 EAK89282.1 - 0.33 11.6 1.5 39 5.2 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Ribosomal_L11_N PF03946.9 EAK89283.1 - 3e-17 61.8 0.9 1e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EAK89283.1 - 8.3e-11 41.8 0.3 1.4e-10 41.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain STIL_N PF15253.1 EAK89283.1 - 0.0058 15.3 0.1 0.0072 15.0 0.1 1.1 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus Prefoldin_2 PF01920.15 EAK89284.1 - 5.5e-18 64.6 9.5 7.6e-18 64.2 6.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EAK89284.1 - 0.00017 21.1 5.9 0.00037 20.1 4.1 1.7 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EAK89284.1 - 0.0033 17.1 3.3 0.0085 15.8 1.7 1.9 1 1 1 2 2 2 1 Prefoldin subunit COG5 PF10392.4 EAK89284.1 - 0.026 14.4 0.6 0.026 14.4 0.4 2.3 2 1 0 2 2 2 0 Golgi transport complex subunit 5 SIR2_2 PF13289.1 EAK89284.1 - 0.087 12.7 0.2 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 SIR2-like domain Spectrin PF00435.16 EAK89284.1 - 0.15 12.3 5.1 4.5 7.6 2.1 2.1 2 0 0 2 2 2 0 Spectrin repeat BDV_P24 PF06595.6 EAK89284.1 - 0.16 11.6 2.2 0.16 11.6 0.9 1.3 1 1 0 1 1 1 0 Borna disease virus P24 protein CALCOCO1 PF07888.6 EAK89284.1 - 0.28 9.4 7.0 0.36 9.0 4.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1664 PF07889.7 EAK89284.1 - 0.45 10.3 5.1 0.64 9.8 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) RE_Alw26IDE PF09665.5 EAK89284.1 - 1.6 7.3 7.0 1.8 7.1 4.8 1.0 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) Fib_alpha PF08702.5 EAK89284.1 - 3.5 7.7 6.8 1.3 9.1 0.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 EAK89284.1 - 4.4 6.8 6.7 4.6 6.8 2.0 2.2 1 1 0 2 2 2 0 Septum formation initiator Myb_DNA-binding PF00249.26 EAK89285.1 - 1.9e-44 149.4 9.7 4.2e-10 39.5 0.0 6.8 6 1 0 6 6 6 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAK89285.1 - 1e-38 131.2 32.1 2.7e-13 49.7 1.5 6.8 3 1 4 7 7 7 5 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EAK89285.1 - 0.0016 18.4 11.0 0.0092 16.0 0.1 5.5 5 1 0 5 5 5 1 Myb/SANT-like DNA-binding domain Guanylate_cyc PF00211.15 EAK89286.1 - 8e-69 230.6 0.8 1.4e-34 119.0 0.0 3.7 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain E1-E2_ATPase PF00122.15 EAK89286.1 - 8.2e-12 44.6 0.0 8.2e-12 44.6 0.0 3.1 2 1 1 3 3 3 1 E1-E2 ATPase WD40 PF00400.27 EAK89287.1 - 1.8e-28 97.3 18.9 8.1e-06 25.5 0.2 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat Synaptobrevin PF00957.16 EAK89288.1 - 3.4e-12 45.8 0.2 4.6e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Ion_trans PF00520.26 EAK89288.1 - 0.034 13.3 1.4 0.043 13.0 1.0 1.1 1 0 0 1 1 1 0 Ion transport protein ESSS PF10183.4 EAK89288.1 - 0.14 12.5 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3915 PF13054.1 EAK89288.1 - 0.28 11.1 2.3 0.27 11.1 0.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) 2OG-FeII_Oxy_2 PF13532.1 EAK89289.1 - 3.7e-06 26.9 0.0 3.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DnaJ PF00226.26 EAK89290.1 - 1e-16 60.4 0.6 3.9e-16 58.5 0.4 1.9 1 1 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 EAK89290.1 - 2.4e-09 36.5 1.0 3.9e-09 35.8 0.7 1.4 1 0 0 1 1 1 1 CSL zinc finger BCAS2 PF05700.6 EAK89290.1 - 0.034 13.5 0.3 0.043 13.2 0.2 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) FtsJ PF01728.14 EAK89291.1 - 6.8e-66 221.7 0.0 8.2e-66 221.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Arf PF00025.16 EAK89292.1 - 8.7e-78 259.5 0.1 9.9e-78 259.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EAK89292.1 - 1.7e-13 50.1 0.0 2.1e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EAK89292.1 - 1.4e-12 47.2 0.0 1.6e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EAK89292.1 - 1.3e-10 40.8 0.0 1.5e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EAK89292.1 - 1.4e-09 37.1 0.7 1.4e-06 27.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EAK89292.1 - 1.8e-09 38.1 0.0 2.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EAK89292.1 - 6.8e-06 26.0 0.0 9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAK89292.1 - 0.0048 16.3 0.1 0.031 13.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EAK89292.1 - 0.0081 15.2 0.1 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EAK89292.1 - 0.071 12.9 0.1 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain Ribosomal_L7Ae PF01248.21 EAK89293.1 - 1.5e-21 75.7 0.3 2.4e-21 75.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EAK89293.1 - 0.07 12.9 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 NMT PF01233.14 EAK89295.1 - 2e-59 199.8 0.2 4.7e-59 198.6 0.1 1.6 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EAK89295.1 - 1.5e-53 181.0 8.6 4.3e-45 153.4 3.7 3.0 2 1 1 3 3 3 2 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EAK89295.1 - 9.2e-05 22.3 0.0 0.00032 20.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EAK89295.1 - 0.0024 17.9 0.1 0.01 16.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain BBP1_N PF15271.1 EAK89295.1 - 0.062 13.6 1.1 1.1 9.5 0.0 2.6 2 1 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein RNA_pol_Rpb4 PF03874.11 EAK89296.1 - 6e-11 42.3 0.0 8.5e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 UQ_con PF00179.21 EAK89297.1 - 4.3e-50 168.7 0.0 4.9e-50 168.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EAK89297.1 - 0.00041 20.2 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EAK89297.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.4 1 1 0 1 1 1 0 UEV domain SMK-1 PF04802.10 EAK89298.1 - 7.5e-25 87.5 12.1 2.4e-24 85.9 8.4 2.0 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Ran_BP1 PF00638.13 EAK89298.1 - 0.023 14.7 0.1 0.089 12.8 0.0 2.1 2 0 0 2 2 2 0 RanBP1 domain Proteasome PF00227.21 EAK89299.1 - 4.9e-37 127.0 0.1 6.2e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAK89299.1 - 1.5e-11 43.3 0.0 2.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribosomal_L14e PF01929.12 EAK89300.1 - 3.7e-27 94.4 1.4 4.8e-27 94.1 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 DUF4407 PF14362.1 EAK89302.1 - 0.68 8.8 5.9 0.54 9.1 2.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Neisseria_TspB PF05616.8 EAK89302.1 - 2.4 6.4 9.3 4.8 5.4 6.4 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF4140 PF13600.1 EAK89302.1 - 3.4 8.1 5.6 0.65 10.4 0.4 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PCI_Csn8 PF10075.4 EAK89303.1 - 0.08 12.7 0.2 0.12 12.0 0.1 1.4 1 1 0 1 1 1 0 COP9 signalosome, subunit CSN8 Myosin_head PF00063.16 EAK89304.1 - 1.3e-160 535.8 7.3 1.2e-159 532.5 5.1 2.2 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 EAK89304.1 - 0.021 14.9 0.0 0.062 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAK89304.1 - 0.023 13.8 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EAK89304.1 - 0.29 10.9 0.0 0.56 10.0 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Prefoldin PF02996.12 EAK89305.1 - 2.9e-19 68.8 1.0 2.9e-19 68.8 0.7 1.6 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 EAK89305.1 - 4.7e-05 23.0 0.6 0.00015 21.4 0.0 2.1 2 1 0 2 2 2 1 Prefoldin subunit IMS_C PF11799.3 EAK89305.1 - 0.02 14.7 0.3 0.042 13.7 0.2 1.4 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain Mgr1 PF08602.5 EAK89305.1 - 0.27 10.2 4.7 0.044 12.8 0.9 1.6 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit IncA PF04156.9 EAK89305.1 - 2.8 7.4 10.2 13 5.3 1.9 2.9 3 0 0 3 3 3 0 IncA protein DivIVA PF05103.8 EAK89305.1 - 4.7 7.2 19.6 1.6 8.7 0.2 3.0 3 0 0 3 3 3 0 DivIVA protein Pkinase PF00069.20 EAK89306.1 - 1e-66 224.7 0.0 2.3e-66 223.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 EAK89306.1 - 5.6e-55 183.1 2.4 1.3e-17 63.3 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 EAK89306.1 - 4.5e-29 101.3 0.0 7.7e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAK89306.1 - 3.5e-09 36.0 0.0 1e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EAK89306.1 - 0.005 16.6 0.0 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EAK89306.1 - 0.078 12.0 0.0 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4646 PF15496.1 EAK89307.1 - 0.037 14.0 0.3 0.091 12.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) zf-CCCH PF00642.19 EAK89308.1 - 2.3e-05 23.9 18.5 0.00011 21.8 1.2 4.3 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EAK89308.1 - 1.9 8.6 20.3 0.81 9.7 1.5 3.6 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type zf-C3H1 PF10650.4 EAK89308.1 - 9.4 5.8 9.5 0.91 9.0 1.2 2.6 2 0 0 2 2 2 0 Putative zinc-finger domain DEAD PF00270.24 EAK89310.1 - 5.6e-41 139.8 0.2 1.3e-40 138.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK89310.1 - 9.9e-18 63.7 0.0 4.3e-17 61.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AP2 PF00847.15 EAK89311.1 - 1.2e-10 41.3 2.9 2.3e-10 40.4 2.0 1.5 1 0 0 1 1 1 1 AP2 domain LIF_OSM PF01291.12 EAK89312.1 - 0.073 12.9 0.4 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 LIF / OSM family DUF2040 PF09745.4 EAK89313.1 - 1.6e-09 37.6 12.7 1.6e-09 37.6 8.8 2.0 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Bac_small_YrzI PF09501.5 EAK89313.1 - 0.72 9.8 5.2 27 4.7 2.9 3.0 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) CAML PF14963.1 EAK89313.1 - 2.5 7.3 9.2 0.24 10.7 2.6 1.8 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand DNA_pol_E_B PF04042.11 EAK89315.1 - 1.7e-31 109.1 1.2 3.1e-31 108.2 0.8 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B TFIIB PF00382.14 EAK89316.1 - 4.6e-12 45.5 1.4 3.4e-05 23.5 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EAK89316.1 - 1.6e-10 40.0 1.9 1.6e-10 40.0 1.3 2.3 2 0 0 2 2 2 1 TFIIB zinc-binding DUF1936 PF09151.5 EAK89316.1 - 0.039 13.4 0.3 7.7 6.1 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1936) zf-ribbon_3 PF13248.1 EAK89316.1 - 0.044 13.0 1.0 0.12 11.6 0.7 1.8 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 EAK89316.1 - 0.15 11.9 1.1 0.34 10.7 0.1 2.1 2 0 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.1 EAK89316.1 - 2.3 7.9 4.8 22 4.8 0.1 2.8 3 0 0 3 3 3 0 Nudix N-terminal U3_assoc_6 PF08640.6 EAK89317.1 - 1.2e-25 89.0 8.9 1.5e-25 88.7 3.2 2.8 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 Pep3_Vps18 PF05131.9 EAK89318.1 - 7.9e-09 35.1 2.2 0.00098 18.5 0.1 3.6 2 1 1 3 3 3 2 Pep3/Vps18/deep orange family Vps39_2 PF10367.4 EAK89318.1 - 0.041 14.0 0.9 0.28 11.3 0.0 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 EAK89318.1 - 0.091 12.6 0.1 0.091 12.6 0.1 2.8 3 0 0 3 3 3 0 Ring finger domain zf-rbx1 PF12678.2 EAK89318.1 - 1.1 9.4 3.3 1 9.5 0.1 2.6 3 0 0 3 3 3 0 RING-H2 zinc finger zf-rbx1 PF12678.2 EAK89319.1 - 8.2e-36 121.9 12.8 1.3e-35 121.3 8.8 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EAK89319.1 - 4.3e-18 64.9 9.8 6.1e-18 64.4 6.8 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EAK89319.1 - 2.9e-08 33.3 12.2 3.2e-07 30.0 8.4 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EAK89319.1 - 0.00051 19.6 10.4 0.057 13.0 7.3 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAK89319.1 - 0.00068 19.2 11.5 0.0046 16.5 8.0 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK89319.1 - 0.021 14.5 10.3 0.14 11.9 7.1 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAK89319.1 - 0.029 14.3 13.0 0.91 9.6 9.2 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EAK89319.1 - 0.077 12.9 8.9 1.1 9.2 6.5 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain zf-Nse PF11789.3 EAK89319.1 - 0.18 11.3 2.0 0.43 10.1 1.4 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H_2 PF13832.1 EAK89319.1 - 0.65 10.0 10.8 3.5 7.6 7.5 2.2 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EAK89319.1 - 0.93 9.6 11.4 1.1e+02 3.0 7.6 2.5 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.1 EAK89319.1 - 5.1 7.0 8.0 0.52 10.2 0.3 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EAK89319.1 - 7.5 6.3 7.7 8.2 6.2 1.4 2.5 1 1 1 2 2 2 0 RING-type zinc-finger DUF2423 PF10338.4 EAK89320.1 - 1.4e-06 28.1 2.2 3.3e-06 26.9 1.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Lung_7-TM_R PF06814.8 EAK89321.1 - 0.03 13.2 22.2 0.061 12.2 15.4 1.5 1 0 0 1 1 1 0 Lung seven transmembrane receptor Rad21_Rec8 PF04824.11 EAK89326.1 - 3.2e-08 32.6 0.0 6e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EAK89326.1 - 0.27 10.7 5.7 0.068 12.7 0.3 2.4 2 1 0 2 2 2 0 ScpA/B protein YjgP_YjgQ PF03739.9 EAK89326.1 - 8.4 5.0 5.9 1 8.0 1.2 1.5 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family tRNA-synt_2b PF00587.20 EAK89327.1 - 2.1e-58 196.7 0.1 4.4e-58 195.6 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EAK89327.1 - 4.7e-21 74.5 0.0 1.6e-20 72.8 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain Actin PF00022.14 EAK89329.1 - 3.2e-32 111.4 0.0 7e-32 110.3 0.0 1.5 1 1 0 1 1 1 1 Actin Sec1 PF00995.18 EAK89330.1 - 1.5e-80 271.4 13.0 2.1e-80 271.0 9.0 1.2 1 0 0 1 1 1 1 Sec1 family Ribosomal_S4e PF00900.15 EAK89331.1 - 0.028 14.0 0.3 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 Ribosomal family S4e FlaC_arch PF05377.6 EAK89331.1 - 5.7 6.9 10.8 0.17 11.8 1.0 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Nrap PF03813.9 EAK89332.1 - 6.8e-76 255.6 25.8 2.7e-58 197.3 8.9 3.2 3 0 0 3 3 3 3 Nrap protein GTP_EFTU PF00009.22 EAK89333.1 - 2.4e-33 115.1 0.0 3.7e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EAK89333.1 - 0.00028 20.8 0.2 0.0021 18.0 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EAK89333.1 - 0.015 14.6 3.5 0.015 14.6 0.0 2.5 3 0 0 3 3 3 0 Ras family Dynamin_N PF00350.18 EAK89333.1 - 0.087 12.6 4.2 1.6 8.5 0.4 3.1 2 1 0 2 2 2 0 Dynamin family PBP1_TM PF14812.1 EAK89333.1 - 3.6 7.9 4.7 7.4 6.9 3.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CRAL_TRIO PF00650.15 EAK89334.1 - 1.7e-06 27.6 0.2 3.1e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain DUF1027 PF06265.6 EAK89335.1 - 0.092 12.6 1.0 3.3 7.6 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1027) Pox_LP_H2 PF03356.10 EAK89335.1 - 4.2 6.9 6.6 4.2 7.0 0.2 2.0 1 1 1 2 2 2 0 Viral late protein H2 Aa_trans PF01490.13 EAK89336.1 - 2.6e-26 92.0 43.2 3.1e-26 91.8 29.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Innate_immun PF12782.2 EAK89337.1 - 2.5 7.2 12.9 4.2 6.5 8.9 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family IFNGR1 PF07140.6 EAK89338.1 - 0.14 11.8 1.1 0.16 11.6 0.7 1.1 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) DNA_pol_B_exo2 PF10108.4 EAK89338.1 - 0.16 11.4 1.4 0.16 11.4 0.5 1.4 1 1 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB NYD-SP28 PF14772.1 EAK89338.1 - 0.28 11.2 5.0 0.36 10.9 3.5 1.3 1 0 0 1 1 1 0 Sperm tail Mei5 PF10376.4 EAK89338.1 - 0.29 10.6 12.6 0.088 12.3 1.3 2.0 1 1 1 2 2 2 0 Double-strand recombination repair protein HECT PF00632.20 EAK89339.1 - 1.3e-91 307.0 8.2 1.3e-91 307.0 5.7 3.6 3 2 1 4 4 4 1 HECT-domain (ubiquitin-transferase) Abhydrolase_5 PF12695.2 EAK89340.1 - 0.11 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 EAK89341.1 - 3.7e-50 170.5 0.3 1.5e-49 168.5 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK89341.1 - 4.5e-23 81.6 0.0 1.5e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EAK89341.1 - 0.00049 19.1 0.6 0.002 17.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DNA_pol_B_exo1 PF03104.14 EAK89342.1 - 1.3e-51 175.3 11.4 3.1e-51 174.1 6.3 2.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.7 EAK89342.1 - 4.7e-18 64.9 11.6 2.4e-10 39.5 1.2 4.0 3 1 0 3 3 3 2 Domain of unknown function (DUF1744) DNA_pol_B PF00136.16 EAK89342.1 - 1.2e-17 63.8 4.2 1.8e-16 60.0 1.5 3.6 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EAK89342.1 - 3.8e-07 29.8 2.3 2.7e-05 23.7 0.0 3.1 3 0 0 3 3 3 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Sec23_trunk PF04811.10 EAK89343.1 - 3.1e-18 66.0 0.3 9.3e-18 64.4 0.1 1.9 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EAK89343.1 - 2.2e-16 60.1 0.0 2.2e-16 60.1 0.0 2.5 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EAK89343.1 - 2e-12 46.4 7.7 5.2e-12 45.1 5.4 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 EAK89343.1 - 9.6e-09 34.6 0.2 3.8e-08 32.6 0.1 2.0 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 EAK89343.1 - 0.0064 16.1 0.0 0.022 14.4 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat DNA_pol_B_exo2 PF10108.4 EAK89343.1 - 0.056 12.9 0.0 0.056 12.9 0.0 1.9 2 0 0 2 2 2 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Clathrin PF00637.15 EAK89344.1 - 1.2e-151 498.2 62.5 9.9e-32 109.5 1.1 10.0 10 0 0 10 10 10 8 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EAK89344.1 - 1.1e-18 66.8 0.1 3.3e-16 58.9 0.0 4.1 4 0 0 4 4 4 1 Clathrin-H-link TPR_8 PF13181.1 EAK89344.1 - 4.9e-05 22.8 0.9 0.66 9.8 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAK89344.1 - 0.00027 20.5 1.5 3.2 7.4 0.0 5.6 6 0 0 6 6 6 1 TPR repeat TPR_2 PF07719.12 EAK89344.1 - 0.0025 17.6 0.3 53 4.0 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAK89344.1 - 0.0067 16.1 1.3 51 4.0 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Clathrin_propel PF01394.15 EAK89344.1 - 0.0094 16.1 0.2 3.4 8.1 0.0 3.6 3 0 0 3 3 3 1 Clathrin propeller repeat TPR_12 PF13424.1 EAK89344.1 - 0.011 15.6 3.8 18 5.3 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAK89344.1 - 0.083 12.5 11.9 5.3 6.8 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Amidohydro_5 PF13594.1 EAK89344.1 - 0.19 11.5 0.0 0.48 10.2 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase RNA_pol_A_CTD PF03118.10 EAK89345.1 - 0.0001 21.6 8.2 0.05 13.0 1.8 4.0 3 1 0 3 3 3 2 Bacterial RNA polymerase, alpha chain C terminal domain IKKbetaNEMObind PF12179.3 EAK89345.1 - 0.072 12.9 0.1 0.072 12.9 0.1 2.4 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain DUF1287 PF06940.6 EAK89345.1 - 0.46 9.8 4.8 0.23 10.8 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1287) Tox-HDC PF15656.1 EAK89345.1 - 2 8.6 6.3 21 5.3 0.1 3.0 3 1 0 3 3 3 0 Toxin with a H, D/N and C signature SMC_N PF02463.14 EAK89346.1 - 1.4e-13 50.5 0.0 4.4e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EAK89346.1 - 0.00022 20.6 0.1 0.0005 19.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Peptidase_C2 PF00648.16 EAK89347.1 - 7e-25 87.6 1.0 6.4e-22 77.9 0.4 2.6 2 1 0 2 2 2 2 Calpain family cysteine protease TP6A_N PF04406.9 EAK89350.1 - 9.1e-19 66.8 0.3 2.2e-18 65.6 0.2 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase PORR PF11955.3 EAK89351.1 - 6.6e-05 21.8 0.1 0.0063 15.3 0.0 2.3 2 0 0 2 2 2 2 Plant organelle RNA recognition domain TPT PF03151.11 EAK89352.1 - 1.9e-17 63.3 39.9 5.1e-17 61.9 14.5 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EAK89352.1 - 7.5e-06 25.0 38.0 1.1e-05 24.5 26.3 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EAK89352.1 - 1.9e-05 24.6 41.5 0.0001 22.3 13.3 3.3 2 2 1 3 3 3 2 EamA-like transporter family FHIPEP PF00771.15 EAK89353.1 - 3.1 6.0 19.2 7 4.8 13.3 1.5 1 0 0 1 1 1 0 FHIPEP family GPI-anchored PF10342.4 EAK89354.1 - 0.11 12.9 0.5 0.4 11.1 0.3 2.0 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3951 PF13131.1 EAK89354.1 - 2.9 7.7 7.7 6.2 6.6 4.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) Acyltransferase PF01553.16 EAK89355.1 - 1.6e-11 43.7 0.0 4.5e-11 42.3 0.0 1.8 2 1 0 2 2 2 1 Acyltransferase DDOST_48kD PF03345.9 EAK89355.1 - 0.036 12.5 0.3 0.036 12.5 0.2 1.4 2 0 0 2 2 2 0 Oligosaccharyltransferase 48 kDa subunit beta Glyco_hydro_31 PF01055.21 EAK89356.1 - 3.6e-93 312.8 13.2 1.6e-92 310.6 9.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EAK89356.1 - 3.5e-11 42.7 0.2 3.5e-11 42.7 0.1 3.2 3 0 0 3 3 3 1 Galactose mutarotase-like PP2C_2 PF13672.1 EAK89357.1 - 1e-07 31.5 0.0 2.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EAK89357.1 - 1.4e-05 24.9 0.0 0.11 12.1 0.0 3.1 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EAK89357.1 - 0.0006 19.2 2.3 0.079 12.3 0.0 2.7 3 0 0 3 3 3 2 Protein phosphatase 2C Sin_N PF04801.8 EAK89358.1 - 1.5e-29 103.1 3.9 2.2e-18 66.3 0.1 2.6 3 0 0 3 3 3 2 Sin-like protein conserved region RNA_GG_bind PF10258.4 EAK89359.1 - 1.5e-29 101.4 0.1 2.3e-29 100.9 0.1 1.3 1 0 0 1 1 1 1 PHAX RNA-binding domain CTD_bind PF04818.8 EAK89360.1 - 0.0093 16.1 0.3 0.0093 16.1 0.2 2.4 3 0 0 3 3 3 1 RNA polymerase II-binding domain. SEO_N PF14576.1 EAK89360.1 - 0.015 14.5 1.0 0.8 8.9 0.0 2.5 1 1 2 3 3 3 0 Sieve element occlusion N-terminus CsgE PF10627.4 EAK89360.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Curli assembly protein CsgE PRD PF00874.15 EAK89360.1 - 1.7 8.8 5.7 0.4 10.8 0.8 2.4 3 0 0 3 3 3 0 PRD domain Y_phosphatase3 PF13350.1 EAK89361.1 - 3.4e-19 69.6 0.0 1.8e-11 44.5 0.0 2.5 1 1 1 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EAK89361.1 - 7.6e-06 25.9 0.0 2.7e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EAK89361.1 - 0.00061 19.1 0.8 0.005 16.2 0.0 2.7 2 1 1 3 3 3 1 Tyrosine phosphatase family FH2 PF02181.18 EAK89362.1 - 1e-39 136.5 10.6 1e-39 136.5 7.4 3.5 2 1 1 3 3 3 2 Formin Homology 2 Domain UCH PF00443.24 EAK89365.1 - 1.7e-55 188.0 0.0 4.7e-55 186.5 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAK89365.1 - 6.8e-28 97.9 0.2 9.1e-23 81.1 0.0 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EAK89365.1 - 0.00041 19.8 0.2 0.0032 16.9 0.0 2.6 3 1 0 3 3 3 1 Ubiquitin-specific protease C-terminal Drc1-Sld2 PF11719.3 EAK89366.1 - 0.005 15.9 3.0 0.005 15.9 2.1 2.4 2 1 1 3 3 3 1 DNA replication and checkpoint protein Pro_isomerase PF00160.16 EAK89367.1 - 3e-41 141.1 0.2 3.8e-41 140.8 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-CCCH PF00642.19 EAK89368.1 - 0.00021 20.8 4.2 0.00038 20.0 2.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF367 PF04034.8 EAK89369.1 - 6.2e-40 135.7 0.0 1.1e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EAK89369.1 - 1.4e-05 24.5 0.4 2.4e-05 23.8 0.3 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Ycf1 PF05758.7 EAK89369.1 - 0.00024 18.9 9.0 0.00024 18.9 6.3 1.2 1 0 0 1 1 1 1 Ycf1 CDC45 PF02724.9 EAK89369.1 - 0.002 16.2 26.9 0.002 16.2 18.6 1.4 2 0 0 2 2 2 1 CDC45-like protein VID27 PF08553.5 EAK89369.1 - 0.003 15.8 22.8 0.0058 14.9 15.8 1.5 1 0 0 1 1 1 1 VID27 cytoplasmic protein SDA1 PF05285.7 EAK89369.1 - 0.0035 16.6 38.4 0.0035 16.6 26.6 1.5 2 0 0 2 2 2 1 SDA1 Nop14 PF04147.7 EAK89369.1 - 0.014 13.3 49.9 0.024 12.5 34.6 1.3 1 0 0 1 1 1 0 Nop14-like family DUF2413 PF10310.4 EAK89369.1 - 0.49 9.1 22.4 0.7 8.6 15.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Hid1 PF12722.2 EAK89369.1 - 0.54 7.8 13.3 0.78 7.3 9.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 EAK89369.1 - 0.6 8.5 47.2 1.1 7.6 32.7 1.4 1 0 0 1 1 1 0 Daxx Family Presenilin PF01080.12 EAK89369.1 - 1 8.1 17.0 1.6 7.5 11.7 1.2 1 0 0 1 1 1 0 Presenilin SAPS PF04499.10 EAK89369.1 - 1.7 7.2 18.3 2.3 6.7 12.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.1 EAK89369.1 - 2.5 6.5 11.7 3.5 6.0 8.1 1.3 1 0 0 1 1 1 0 Raftlin DUF4045 PF13254.1 EAK89369.1 - 7.8 5.6 16.2 12 5.0 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Zip PF02535.17 EAK89369.1 - 8.9 5.2 12.1 13 4.6 8.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter MFS_1 PF07690.11 EAK89371.1 - 1.5e-35 122.6 56.8 1.3e-26 93.1 2.5 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF3883 PF13020.1 EAK89372.1 - 1.5e-09 37.4 0.1 1.6e-08 34.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.1 EAK89372.1 - 6.9e-07 29.0 0.0 2.1e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_pol_E_B PF04042.11 EAK89373.1 - 1.7e-32 112.4 0.5 2.4e-32 111.8 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PRA1 PF03208.14 EAK89374.1 - 7.9e-34 116.2 2.5 1.1e-33 115.7 1.8 1.1 1 0 0 1 1 1 1 PRA1 family protein Claudin_2 PF13903.1 EAK89374.1 - 0.011 15.4 0.8 0.016 14.9 0.6 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction YwiC PF14256.1 EAK89374.1 - 0.25 11.4 4.3 3.4 7.7 2.4 2.0 1 1 1 2 2 2 0 YwiC-like protein SUR7 PF06687.7 EAK89374.1 - 9.4 5.7 12.5 1.5e+02 1.7 8.0 2.0 1 1 0 1 1 1 0 SUR7/PalI family KH_1 PF00013.24 EAK89375.1 - 0.00038 20.0 0.0 0.00089 18.8 0.0 1.6 1 0 0 1 1 1 1 KH domain FlhE PF06366.8 EAK89375.1 - 0.057 13.2 0.0 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Flagellar protein FlhE YkyA PF10368.4 EAK89377.1 - 0.0026 17.1 5.9 0.32 10.3 0.1 2.0 1 1 1 2 2 2 2 Putative cell-wall binding lipoprotein DUF4559 PF15112.1 EAK89377.1 - 0.013 14.6 3.0 0.015 14.4 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF842 PF05811.8 EAK89377.1 - 0.024 14.1 0.3 0.032 13.7 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) YbfN PF13982.1 EAK89377.1 - 0.039 14.1 0.0 0.085 13.0 0.0 1.6 1 0 0 1 1 1 0 YbfN-like lipoprotein DUF948 PF06103.6 EAK89377.1 - 0.044 13.6 2.3 0.42 10.4 0.6 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Metal_resist PF13801.1 EAK89377.1 - 0.045 13.7 0.7 0.061 13.3 0.5 1.2 1 0 0 1 1 1 0 Heavy-metal resistance Sec5 PF15469.1 EAK89377.1 - 0.048 13.3 3.2 0.078 12.7 2.2 1.3 1 1 0 1 1 1 0 Exocyst complex component Sec5 GAS PF13851.1 EAK89377.1 - 0.049 12.8 10.4 0.06 12.5 7.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EAK89377.1 - 0.056 13.0 8.4 0.082 12.4 5.9 1.3 1 0 0 1 1 1 0 IncA protein ADIP PF11559.3 EAK89377.1 - 0.077 12.8 8.3 0.087 12.7 5.3 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding eIF3_N PF09440.5 EAK89377.1 - 0.11 12.6 3.1 0.13 12.4 1.9 1.4 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain Mer2 PF09074.5 EAK89377.1 - 0.12 12.2 5.5 0.22 11.4 3.8 1.5 1 1 0 1 1 1 0 Mer2 AKNA PF12443.3 EAK89377.1 - 0.14 12.2 5.3 0.24 11.4 2.0 2.0 1 1 1 2 2 2 0 AT-hook-containing transcription factor CorA PF01544.13 EAK89377.1 - 0.14 11.1 3.4 0.16 10.9 2.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Seryl_tRNA_N PF02403.17 EAK89377.1 - 0.17 11.9 8.8 0.43 10.6 6.1 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 EAK89377.1 - 0.18 11.7 9.9 0.21 11.5 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Occludin_ELL PF07303.8 EAK89377.1 - 0.18 12.5 5.0 0.48 11.1 3.2 1.8 1 1 1 2 2 2 0 Occludin homology domain DUF4509 PF14970.1 EAK89377.1 - 0.18 11.4 2.3 0.21 11.2 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) VIT1 PF01988.14 EAK89377.1 - 0.18 11.2 3.2 0.19 11.1 2.2 1.1 1 0 0 1 1 1 0 VIT family DUF4220 PF13968.1 EAK89377.1 - 0.25 10.4 1.0 0.26 10.3 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) SlyX PF04102.7 EAK89377.1 - 0.44 10.9 2.9 0.55 10.6 1.3 1.8 1 1 0 1 1 1 0 SlyX OmpH PF03938.9 EAK89377.1 - 0.47 10.3 5.2 0.68 9.8 3.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 EAK89377.1 - 0.57 8.5 7.1 0.63 8.3 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4047 PF13256.1 EAK89377.1 - 0.61 10.0 5.1 0.76 9.7 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) PGC7_Stella PF15549.1 EAK89377.1 - 0.74 9.7 4.6 0.85 9.5 2.9 1.4 1 1 0 1 1 1 0 PGC7/Stella/Dppa3 domain TPX2 PF06886.6 EAK89377.1 - 0.82 9.7 6.8 4.3 7.4 0.0 2.4 2 1 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) APG6 PF04111.7 EAK89377.1 - 1 8.3 9.8 1.4 7.8 6.8 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EAK89377.1 - 1.6 6.4 4.0 1.8 6.3 2.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4363 PF14276.1 EAK89377.1 - 2 8.1 5.6 4.7 6.9 0.6 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4363) Rho_Binding PF08912.6 EAK89377.1 - 2 8.7 12.6 0.63 10.3 2.1 2.3 1 1 1 2 2 2 0 Rho Binding DUF4140 PF13600.1 EAK89377.1 - 2.2 8.7 6.2 1.1 9.7 2.2 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 EAK89377.1 - 2.5 8.5 6.9 4 7.8 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) M_domain PF12938.2 EAK89380.1 - 5.9 6.6 19.7 12 5.6 13.7 1.5 1 0 0 1 1 1 0 M domain of GW182 Rad60-SLD PF11976.3 EAK89382.1 - 6.2e-10 38.6 0.7 0.8 9.4 0.0 7.5 8 1 0 8 8 8 3 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EAK89382.1 - 2.7e-09 36.3 0.0 0.57 9.6 0.0 7.4 9 0 0 9 9 9 3 Ubiquitin family Ubiquitin_2 PF14560.1 EAK89382.1 - 1.2e-05 25.5 0.0 0.093 13.0 0.0 4.5 4 0 0 4 4 4 1 Ubiquitin-like domain DUF3972 PF13118.1 EAK89385.1 - 0.012 15.7 1.0 0.012 15.7 0.7 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3972) DIOX_N PF14226.1 EAK89385.1 - 0.11 13.0 1.5 0.6 10.6 0.0 2.6 2 1 1 3 3 3 0 non-haem dioxygenase in morphine synthesis N-terminal Cep57_CLD_2 PF14197.1 EAK89385.1 - 0.12 12.3 7.2 0.36 10.7 5.0 1.9 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 SURF6 PF04935.7 EAK89386.1 - 1.6e-07 30.8 38.8 1.6e-07 30.8 26.9 1.5 1 1 0 1 1 1 1 Surfeit locus protein 6 AFG1_ATPase PF03969.11 EAK89386.1 - 0.079 11.7 4.4 0.063 12.0 0.6 2.0 2 0 0 2 2 2 0 AFG1-like ATPase E2F_TDP PF02319.15 EAK89387.1 - 7.9e-13 47.7 0.0 1.5e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain LisH PF08513.6 EAK89388.1 - 1.9e-10 40.0 0.2 3.7e-10 39.2 0.2 1.5 1 0 0 1 1 1 1 LisH WD40 PF00400.27 EAK89388.1 - 0.0001 22.0 1.3 0.01 15.7 0.1 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 EAK89388.1 - 0.00092 18.3 0.0 0.0019 17.3 0.0 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus zf-C3HC4 PF00097.20 EAK89389.1 - 1.2e-05 24.8 11.2 2.3e-05 23.9 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK89389.1 - 3.3e-05 23.8 13.2 5.8e-05 23.0 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAK89389.1 - 3.4e-05 23.4 10.8 5.5e-05 22.7 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAK89389.1 - 0.00014 21.6 11.9 0.00023 20.9 8.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EAK89389.1 - 0.00016 21.3 11.1 0.00031 20.4 7.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 EAK89389.1 - 0.023 14.4 6.2 0.042 13.6 4.3 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EAK89389.1 - 0.8 9.4 9.8 2.3 8.0 6.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAK89389.1 - 3.2 7.7 12.6 2.7 7.9 7.5 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EAK89389.1 - 3.3 7.3 10.7 9.5 5.9 7.4 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain VPS9 PF02204.13 EAK89390.1 - 8.3e-25 86.8 1.6 1e-24 86.5 0.2 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain HR1 PF02185.11 EAK89390.1 - 0.1 12.3 1.4 0.34 10.6 1.0 1.9 1 0 0 1 1 1 0 Hr1 repeat ELMO_CED12 PF04727.8 EAK89391.1 - 1.3e-33 115.9 1.7 2.1e-33 115.2 1.2 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PMI_typeI PF01238.16 EAK89393.1 - 1.6e-74 251.1 1.6 1.7e-73 247.7 0.9 2.4 2 1 0 2 2 2 1 Phosphomannose isomerase type I ENTH PF01417.15 EAK89394.1 - 1.1e-34 118.9 0.2 1.9e-34 118.2 0.1 1.4 1 0 0 1 1 1 1 ENTH domain HEAT PF02985.17 EAK89395.1 - 4.9e-18 63.5 4.8 0.0021 18.0 0.1 9.6 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 EAK89395.1 - 5.4e-13 48.9 1.0 0.023 15.1 0.0 8.2 7 1 1 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.1 EAK89395.1 - 1.5e-11 44.3 2.2 0.0045 17.2 0.1 7.6 6 2 2 8 8 8 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EAK89395.1 - 1.2e-09 38.4 10.2 0.011 16.1 0.0 9.5 10 1 1 11 11 11 2 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 EAK89395.1 - 0.0044 16.9 2.8 0.99 9.4 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion Helicase_C_3 PF13625.1 EAK89396.1 - 3.7e-21 75.2 0.0 6.2e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAK89396.1 - 8.6e-14 51.7 5.7 7.6e-13 48.6 0.0 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EAK89396.1 - 3e-10 39.7 0.0 1.6e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Cwf_Cwc_15 PF04889.7 EAK89397.1 - 7.4e-24 84.7 33.2 8.8e-23 81.2 23.0 2.0 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Ribosomal_S8 PF00410.14 EAK89397.1 - 0.075 12.8 4.4 0.056 13.2 0.5 2.1 2 0 0 2 2 2 0 Ribosomal protein S8 DUF413 PF04219.7 EAK89397.1 - 0.35 10.6 3.5 0.24 11.1 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF Spt5_N PF11942.3 EAK89397.1 - 1.7 9.3 26.4 1 10.0 1.1 2.5 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal GNAT_acetyltr_2 PF13718.1 EAK89399.1 - 2.3e-66 222.8 0.0 4.1e-66 222.0 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EAK89399.1 - 2.2e-60 203.2 0.0 4.7e-60 202.2 0.0 1.6 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 EAK89399.1 - 9.9e-32 108.5 0.0 2.4e-31 107.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EAK89399.1 - 5.8e-28 96.9 2.4 3e-27 94.6 0.7 2.8 2 0 0 2 2 2 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 EAK89399.1 - 0.0054 16.7 0.0 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAK89399.1 - 0.011 15.8 0.0 0.098 12.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAK89399.1 - 0.11 12.2 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein Dynamin_N PF00350.18 EAK89400.1 - 1.8e-13 50.6 0.4 1.2e-12 47.9 0.0 2.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EAK89400.1 - 0.0045 16.9 0.8 0.046 13.6 0.6 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2639 PF11121.3 EAK89400.1 - 0.03 13.8 0.5 0.083 12.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2639) Gp23 PF07068.6 EAK89400.1 - 0.21 10.0 0.0 6.1 5.2 0.0 2.1 2 0 0 2 2 2 0 Major capsid protein Gp23 Acetyltransf_1 PF00583.19 EAK89401.1 - 7.2e-07 29.1 0.0 1.2e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EAK89401.1 - 0.00069 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EAK89401.1 - 0.00091 19.3 0.5 0.0031 17.6 0.3 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAK89401.1 - 0.042 13.6 0.2 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TBP PF00352.16 EAK89402.1 - 2.8e-61 202.8 0.0 8.4e-31 105.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) S1 PF00575.18 EAK89403.1 - 1.2e-27 95.8 22.6 5.9e-07 29.4 0.0 10.3 10 1 0 10 10 10 4 S1 RNA binding domain Suf PF05843.9 EAK89403.1 - 3.9e-05 23.5 24.9 0.0013 18.5 0.1 5.0 5 1 1 6 6 6 3 Suppressor of forked protein (Suf) TPR_5 PF12688.2 EAK89403.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_14 PF13428.1 EAK89403.1 - 0.11 13.2 0.0 26 5.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GAPT PF11770.3 EAK89404.1 - 0.0079 15.8 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) E1-E2_ATPase PF00122.15 EAK89407.1 - 2e-29 102.2 0.4 2e-29 102.2 0.2 2.5 3 0 0 3 3 3 1 E1-E2 ATPase P5-ATPase PF12409.3 EAK89407.1 - 3.3e-22 78.5 2.8 1.6e-21 76.3 1.9 2.3 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EAK89407.1 - 6.6e-15 55.7 0.0 1e-13 51.9 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAK89407.1 - 9.7e-14 52.2 0.0 6.4e-05 23.4 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAK89407.1 - 3.7e-05 23.5 0.1 0.0005 19.9 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAK89407.1 - 0.13 11.8 10.2 0.15 11.6 0.4 3.1 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Spore_coat_CotO PF14153.1 EAK89408.1 - 0.0046 16.4 14.6 0.0046 16.4 10.2 2.4 2 1 0 2 2 2 1 Spore coat protein CotO NUP50 PF08911.6 EAK89408.1 - 0.68 10.3 0.0 0.68 10.3 0.0 5.2 4 1 0 4 4 4 0 NUP50 (Nucleoporin 50 kDa) AIF_C PF14721.1 EAK89408.1 - 5.2 7.3 10.1 4.6 7.4 5.0 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4045 PF13254.1 EAK89408.1 - 7.2 5.7 17.1 0.4 9.9 7.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) MIR PF02815.14 EAK89409.1 - 1.3e-07 31.3 0.3 0.0089 15.5 0.1 2.7 1 1 2 3 3 3 2 MIR domain Ins145_P3_rec PF08709.6 EAK89409.1 - 2.7e-07 29.8 0.8 0.00037 19.5 0.0 2.6 1 1 1 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor PCNA_N PF00705.13 EAK89412.1 - 4.1e-44 149.1 1.0 6.9e-44 148.4 0.7 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EAK89412.1 - 4.3e-40 136.5 0.0 1.1e-39 135.2 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 EAK89412.1 - 6.7e-11 41.4 0.5 1.5e-06 27.2 0.2 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EAK89412.1 - 9.8e-05 21.5 0.9 0.00012 21.3 0.7 1.2 1 1 0 1 1 1 1 Rad9 DNA_pol3_beta PF00712.14 EAK89412.1 - 0.024 14.5 0.3 7.2 6.5 0.0 2.9 2 1 0 3 3 3 0 DNA polymerase III beta subunit, N-terminal domain PARG_cat PF05028.9 EAK89413.1 - 3.5e-45 154.7 0.2 5e-45 154.2 0.1 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Histone PF00125.19 EAK89414.1 - 9.3e-28 96.1 0.1 1.2e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAK89414.1 - 0.00012 22.0 0.1 0.00021 21.2 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YdfA_immunity PF12127.3 EAK89414.1 - 0.12 11.2 0.1 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 SigmaW regulon antibacterial Pkinase PF00069.20 EAK89415.1 - 4.8e-54 183.2 2.9 4.8e-54 183.2 2.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK89415.1 - 3.5e-38 131.1 0.6 9.1e-38 129.7 0.4 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAK89415.1 - 2.6e-05 23.3 0.0 6.6e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Actin PF00022.14 EAK89417.1 - 4e-122 407.4 0.0 4.5e-122 407.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EAK89417.1 - 1.1e-06 27.5 0.2 0.0012 17.4 0.0 2.4 3 0 0 3 3 3 2 MreB/Mbl protein HSP70 PF00012.15 EAK89417.1 - 0.21 9.4 0.0 10 3.8 0.0 2.2 2 0 0 2 2 2 0 Hsp70 protein HAP2-GCS1 PF10699.4 EAK89418.1 - 2.3e-17 62.6 0.0 5.1e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Male gamete fusion factor His_Phos_1 PF00300.17 EAK89419.1 - 1.4e-08 34.9 0.0 1.8e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) UL2 PF08196.6 EAK89419.1 - 0.14 11.8 0.3 0.32 10.7 0.2 1.5 1 0 0 1 1 1 0 UL2 protein XRN_N PF03159.13 EAK89421.1 - 7e-98 326.7 1.6 1.1e-97 326.0 0.0 2.2 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus DUF4018 PF13210.1 EAK89422.1 - 0.91 8.8 9.5 0.33 10.3 1.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4018) HALZ PF02183.13 EAK89423.1 - 1.6 8.4 33.4 0.19 11.4 1.2 6.4 5 0 0 5 5 5 0 Homeobox associated leucine zipper zf-AN1 PF01428.11 EAK89424.1 - 5.6e-15 54.9 21.5 8.7e-08 31.9 5.9 2.3 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EAK89424.1 - 1.7e-05 24.9 20.4 0.00012 22.2 3.5 2.3 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain C1_4 PF07975.7 EAK89424.1 - 5.6 7.0 15.6 8.1 6.5 3.1 2.8 2 0 0 2 2 2 0 TFIIH C1-like domain SNF2_N PF00176.18 EAK89425.1 - 9.1e-67 224.9 0.0 9.1e-67 224.9 0.0 2.9 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EAK89425.1 - 6.3e-16 58.0 0.3 1.8e-15 56.5 0.2 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EAK89425.1 - 1.1e-15 57.1 0.1 1.2e-14 53.8 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAK89425.1 - 3.2e-11 43.4 0.0 3.2e-11 43.4 0.0 4.2 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EAK89425.1 - 2.7e-07 30.2 0.0 6.5e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.8 EAK89425.1 - 0.0017 18.0 8.7 0.0017 18.0 6.0 3.2 4 0 0 4 4 4 1 HSA QLQ PF08880.6 EAK89425.1 - 0.098 12.0 0.0 0.49 9.8 0.0 2.2 2 0 0 2 2 2 0 QLQ TetR_C_6 PF13977.1 EAK89425.1 - 0.11 12.5 0.5 0.24 11.4 0.3 1.5 1 0 0 1 1 1 0 Bacterial transcriptional repressor Caps_synth_CapC PF14102.1 EAK89426.1 - 0.089 12.9 6.6 0.13 12.3 4.6 1.3 1 0 0 1 1 1 0 Capsule biosynthesis CapC DUF3341 PF11821.3 EAK89426.1 - 0.57 9.6 6.6 1.1 8.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3341) PNTB PF02233.11 EAK89427.1 - 3.9e-177 589.6 19.7 3.9e-177 589.6 13.7 1.5 2 0 0 2 2 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EAK89427.1 - 1.7e-49 167.6 0.9 3.1e-49 166.7 0.6 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EAK89427.1 - 6.4e-46 155.7 0.0 1.2e-45 154.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EAK89427.1 - 4.5e-31 106.8 5.4 4.5e-31 106.8 3.8 4.7 2 1 3 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EAK89427.1 - 1.6e-07 30.6 0.4 0.017 14.3 0.0 3.7 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EAK89427.1 - 0.00064 19.8 2.0 0.029 14.4 0.5 3.3 3 1 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EAK89427.1 - 0.0036 17.1 0.1 0.012 15.4 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.21 EAK89427.1 - 0.0041 16.6 0.1 0.013 15.0 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPP_enzyme_M PF00205.17 EAK89427.1 - 0.014 15.1 0.4 0.13 11.9 0.1 2.7 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Pyr_redox PF00070.22 EAK89427.1 - 0.044 14.1 0.2 0.18 12.2 0.2 2.2 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 EAK89427.1 - 0.067 13.0 3.1 0.12 12.2 0.2 2.8 3 1 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase CDC45 PF02724.9 EAK89429.1 - 1.4e-42 145.5 4.3 1.1e-41 142.6 3.0 1.9 1 1 0 1 1 1 1 CDC45-like protein DAGK_acc PF00609.14 EAK89430.1 - 2.8e-16 60.0 0.1 2.9e-11 43.7 0.0 3.5 2 1 1 3 3 3 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EAK89430.1 - 1.5e-11 43.8 0.0 4.2e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF371 PF04027.8 EAK89430.1 - 0.029 14.0 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF371) GCC2_GCC3 PF07699.8 EAK89430.1 - 0.36 10.4 6.8 4.2 7.0 1.8 2.7 2 0 0 2 2 2 0 GCC2 and GCC3 V-ATPase_G PF03179.10 EAK89431.1 - 7.1e-07 29.4 12.6 7.1e-07 29.4 8.7 2.4 2 0 0 2 2 2 1 Vacuolar (H+)-ATPase G subunit DUF3823 PF12866.2 EAK89431.1 - 2 7.8 9.2 56 3.1 5.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3823) TFIIF_beta PF02270.10 EAK89432.1 - 2.1e-06 27.7 0.2 3.6e-06 26.9 0.1 1.4 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit RPA_C PF08784.6 EAK89432.1 - 0.00025 21.4 0.5 0.00044 20.6 0.3 1.4 1 0 0 1 1 1 1 Replication protein A C terminal Pkinase_Tyr PF07714.12 EAK89433.1 - 6.5e-64 215.4 0.0 9.4e-64 214.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EAK89433.1 - 1.9e-60 204.2 0.1 4.7e-60 202.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain SAM_1 PF00536.25 EAK89433.1 - 1.4e-09 37.9 0.0 4.1e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EAK89433.1 - 2.8e-08 33.4 0.1 1.3e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) MORN PF02493.15 EAK89433.1 - 0.00011 21.7 11.5 0.5 10.1 0.1 4.2 4 0 0 4 4 4 3 MORN repeat Kinase-like PF14531.1 EAK89433.1 - 0.00036 19.5 0.0 0.00058 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAK89433.1 - 0.045 12.8 0.0 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EAK89434.1 - 1.1e-07 31.2 0.1 2.3e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EAK89434.1 - 0.0021 18.0 0.0 36 4.7 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.2 EAK89434.1 - 0.0049 16.7 5.9 0.014 15.2 0.4 3.4 2 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.1 EAK89434.1 - 0.01 14.8 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FH2 PF02181.18 EAK89435.1 - 1.1e-41 142.9 12.5 9.8e-27 93.7 4.7 2.8 3 0 0 3 3 3 2 Formin Homology 2 Domain SAP PF02037.22 EAK89436.1 - 2e-07 30.3 0.8 4.4e-07 29.2 0.2 1.9 2 0 0 2 2 2 1 SAP domain OST-HTH PF12872.2 EAK89436.1 - 0.00027 20.6 0.0 0.00066 19.4 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain LETM1 PF07766.8 EAK89436.1 - 0.07 12.1 0.0 0.07 12.1 0.0 2.9 3 0 0 3 3 3 0 LETM1-like protein DUF3099 PF11298.3 EAK89437.1 - 0.12 12.1 0.2 0.12 12.1 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3099) DSHCT PF08148.7 EAK89441.1 - 1.7e-53 180.5 0.0 4.5e-53 179.1 0.0 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EAK89441.1 - 1.3e-20 73.5 0.0 3.9e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 EAK89441.1 - 1e-13 51.0 14.7 6.2e-09 35.3 5.3 3.8 2 1 0 2 2 2 2 rRNA-processing arch domain Helicase_C PF00271.26 EAK89441.1 - 4.6e-06 26.3 0.4 3.3e-05 23.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Sushi PF00084.15 EAK89442.1 - 6.8e-06 26.3 1.4 1.8e-05 25.0 0.9 1.8 1 0 0 1 1 1 1 Sushi domain (SCR repeat) Med22 PF06179.7 EAK89443.1 - 0.024 14.6 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex Troponin PF00992.15 EAK89443.1 - 0.031 14.3 0.1 0.053 13.5 0.1 1.3 1 0 0 1 1 1 0 Troponin DUF2746 PF10874.3 EAK89446.1 - 0.093 12.9 0.0 0.25 11.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2746) Porphobil_deam PF01379.15 EAK89447.1 - 0.069 12.0 0.1 0.13 11.1 0.0 1.4 1 1 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain PPP5 PF08321.7 EAK89447.1 - 0.079 12.9 5.1 0.68 9.9 2.2 2.1 2 0 0 2 2 2 0 PPP5 TPR repeat region SHMT PF00464.14 EAK89448.1 - 8.4e-122 406.3 0.0 1.3e-121 405.7 0.0 1.3 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Autophagy_act_C PF03987.10 EAK89450.1 - 2.6e-26 91.5 0.2 4.7e-26 90.7 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_N PF03986.8 EAK89450.1 - 2.3e-25 89.0 0.0 3.1e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_Cterm PF10381.4 EAK89450.1 - 3.1e-11 42.1 1.4 6.8e-11 41.0 1.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal zf-Nse PF11789.3 EAK89451.1 - 3e-19 68.3 1.1 5.8e-19 67.3 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit GMC_oxred_C PF05199.8 EAK89454.1 - 1.4e-28 100.0 0.0 3.4e-28 98.7 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EAK89454.1 - 2.1e-21 76.3 0.1 3.1e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.19 EAK89454.1 - 2.2e-05 23.5 0.0 3.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EAK89454.1 - 2.8e-05 24.4 0.2 0.00022 21.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 EAK89454.1 - 3.7e-05 22.2 0.0 6.6e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor Thi4 PF01946.12 EAK89454.1 - 0.00014 21.0 0.1 0.00034 19.7 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EAK89454.1 - 0.00014 20.8 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EAK89454.1 - 0.0002 20.5 0.0 0.00034 19.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EAK89454.1 - 0.00037 20.4 0.1 0.00037 20.4 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAK89454.1 - 0.00079 19.3 0.1 0.0015 18.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAK89454.1 - 0.002 16.6 0.0 0.0031 16.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EAK89454.1 - 0.0024 16.8 0.2 0.0037 16.1 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EAK89454.1 - 0.02 14.0 0.1 0.03 13.4 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EAK89454.1 - 0.025 14.2 0.1 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EAK89454.1 - 0.077 12.7 0.0 0.57 9.9 0.0 2.4 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 EAK89454.1 - 0.078 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein zf-HIT PF04438.11 EAK89455.1 - 0.00086 18.9 7.6 0.00086 18.9 5.3 1.7 2 0 0 2 2 2 1 HIT zinc finger Peptidase_M16_C PF05193.16 EAK89457.1 - 4.1e-12 46.1 0.1 3.2e-09 36.7 0.0 3.1 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EAK89457.1 - 1.2e-09 38.0 0.1 6.2e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) MyTH4 PF00784.12 EAK89457.1 - 0.055 13.4 2.2 0.066 13.1 0.3 2.1 2 0 0 2 2 2 0 MyTH4 domain SET PF00856.23 EAK89458.1 - 2.5e-22 79.9 0.3 2.5e-22 79.9 0.2 2.4 2 0 0 2 2 2 1 SET domain PHD PF00628.24 EAK89458.1 - 3.2e-11 42.7 97.3 9.6e-06 25.1 5.7 9.5 9 1 1 10 10 10 6 PHD-finger Bromodomain PF00439.20 EAK89458.1 - 6.2e-07 29.2 1.4 6.2e-07 29.2 1.0 2.8 2 0 0 2 2 2 1 Bromodomain C1_1 PF00130.17 EAK89458.1 - 0.0025 17.5 2.3 0.0025 17.5 1.6 8.8 5 2 3 8 8 8 4 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 EAK89458.1 - 0.0033 17.4 3.0 0.0033 17.4 2.1 9.1 11 0 0 11 11 11 3 C1-like domain Prok-RING_1 PF14446.1 EAK89458.1 - 0.0049 16.5 1.4 0.0049 16.5 1.0 8.4 8 1 1 9 9 9 2 Prokaryotic RING finger family 1 Prefoldin_3 PF13758.1 EAK89460.1 - 0.0074 16.0 0.4 0.022 14.5 0.1 2.0 2 0 0 2 2 2 1 Prefoldin subunit SNF2_N PF00176.18 EAK89461.1 - 5.3e-77 258.5 0.3 1.1e-76 257.5 0.2 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAK89461.1 - 4.9e-15 55.1 0.0 1.2e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNA_pol_3_Rpc31 PF11705.3 EAK89461.1 - 0.00047 20.1 29.6 0.00047 20.1 20.5 4.3 4 0 0 4 4 4 2 DNA-directed RNA polymerase III subunit Rpc31 Myb_DNA-binding PF00249.26 EAK89462.1 - 2.6e-05 24.1 0.1 5.7e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3642 PF12182.3 EAK89462.1 - 0.035 14.5 0.1 0.49 10.8 0.2 2.4 2 0 0 2 2 2 0 Bacterial lipoprotein Myb_DNA-bind_6 PF13921.1 EAK89462.1 - 0.059 13.4 0.2 0.17 12.0 0.1 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain Notch PF00066.12 EAK89464.1 - 5.6e-47 157.7 125.7 6.3e-09 35.9 9.3 6.3 4 1 2 6 6 6 6 LNR domain DnaJ PF00226.26 EAK89465.1 - 2.5e-19 68.7 0.2 4.9e-19 67.8 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Wzy_C PF04932.10 EAK89465.1 - 0.093 12.5 0.6 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 O-Antigen ligase LRR_4 PF12799.2 EAK89466.1 - 5.2e-06 25.9 46.7 0.0023 17.5 5.4 6.7 6 2 2 8 8 8 5 Leucine Rich repeats (2 copies) Cyc-maltodext_N PF09087.6 EAK89466.1 - 0.32 10.9 3.5 1.4 8.8 0.2 2.8 2 1 0 2 2 2 0 Cyclomaltodextrinase, N-terminal DnaJ PF00226.26 EAK89469.1 - 4.8e-07 29.4 0.3 1.2e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain CBM_21 PF03370.8 EAK89469.1 - 0.23 11.4 8.2 1.1 9.2 0.2 3.6 2 1 1 3 3 3 0 Putative phosphatase regulatory subunit SUI1 PF01253.17 EAK89470.1 - 3.5e-20 71.5 0.5 6.5e-20 70.7 0.3 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 TraB PF01963.12 EAK89470.1 - 0.026 13.9 0.0 0.036 13.5 0.0 1.1 1 0 0 1 1 1 0 TraB family DUF1777 PF08648.7 EAK89471.1 - 7.3e-19 68.1 5.7 1e-18 67.7 3.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) C2 PF00168.25 EAK89472.1 - 2.1e-25 88.3 0.0 1.2e-05 24.9 0.0 5.7 5 0 0 5 5 5 5 C2 domain FerI PF08151.7 EAK89472.1 - 2e-05 24.4 0.1 0.0015 18.5 0.0 3.2 3 0 0 3 3 3 1 FerI (NUC094) domain Snf7 PF03357.16 EAK89473.1 - 3.5e-10 39.5 12.6 7.1e-10 38.5 8.7 1.4 1 0 0 1 1 1 1 Snf7 Lung_7-TM_R PF06814.8 EAK89474.1 - 2e-37 128.7 24.7 2.7e-37 128.3 17.1 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF441 PF04284.8 EAK89474.1 - 0.027 14.3 2.0 0.053 13.3 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF441) MA3 PF02847.12 EAK89475.1 - 5.3e-19 68.0 2.3 5.3e-19 68.0 1.6 2.1 2 0 0 2 2 2 1 MA3 domain GAT PF03127.9 EAK89476.1 - 0.067 13.1 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 GAT domain EXS PF03124.9 EAK89477.1 - 5.5e-76 255.8 30.1 7.8e-76 255.3 20.9 1.2 1 0 0 1 1 1 1 EXS family AAA_23 PF13476.1 EAK89478.1 - 1.3e-14 55.0 12.6 1.3e-14 55.0 8.8 7.2 1 1 3 4 4 4 1 AAA domain SMC_N PF02463.14 EAK89478.1 - 1.7e-10 40.5 39.7 2.7e-09 36.6 27.5 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EAK89478.1 - 7.1e-05 22.2 0.2 0.00016 21.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EAK89478.1 - 0.0017 18.4 23.8 0.0017 18.4 16.5 7.2 1 1 3 6 6 6 2 AAA domain SbcCD_C PF13558.1 EAK89478.1 - 0.067 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 EAK89478.1 - 0.18 11.2 0.0 0.9 8.9 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family IncA PF04156.9 EAK89478.1 - 3.1 7.3 80.8 0.13 11.8 7.8 5.7 3 2 2 5 5 5 0 IncA protein YjgP_YjgQ PF03739.9 EAK89479.1 - 4.7 5.8 5.5 8.9 4.9 3.8 1.5 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family Alpha_adaptinC2 PF02883.15 EAK89482.1 - 1.5e-07 31.6 0.0 3.8e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain SNF2_N PF00176.18 EAK89483.1 - 1.1e-75 254.2 2.8 1.1e-75 254.2 2.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAK89483.1 - 1.7e-15 56.6 0.4 4.9e-15 55.1 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.8 EAK89483.1 - 1.8e-09 37.2 1.9 5.2e-09 35.7 1.3 1.8 1 0 0 1 1 1 1 HSA tRNA-synt_1 PF00133.17 EAK89484.1 - 7.4e-178 592.2 0.0 8.1e-177 588.8 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EAK89484.1 - 3.2e-33 114.6 0.3 3.2e-33 114.6 0.2 2.5 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EAK89484.1 - 1.7e-15 56.6 4.6 3.6e-07 29.1 0.0 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EAK89484.1 - 2.1e-07 30.4 0.2 8.7e-06 25.1 0.0 2.5 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 EAK89484.1 - 7.6e-05 21.6 0.1 0.00099 18.0 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EAK89484.1 - 0.0015 17.7 1.1 0.018 14.1 0.0 2.9 4 0 0 4 4 4 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.20 EAK89484.1 - 0.064 12.3 0.1 0.5 9.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) PA28_beta PF02252.13 EAK89485.1 - 3.6e-63 211.5 0.2 5.6e-63 210.9 0.2 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit GCR1_C PF12550.3 EAK89485.1 - 0.053 13.3 2.9 0.56 10.1 0.2 2.6 2 1 0 2 2 2 0 Transcriptional activator of glycolytic enzymes GATA PF00320.22 EAK89486.1 - 0.047 13.0 9.4 0.47 9.8 4.5 2.9 2 1 0 2 2 2 0 GATA zinc finger Anophelin PF10731.4 EAK89487.1 - 0.013 15.5 0.4 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito AP2 PF00847.15 EAK89488.1 - 7.5e-14 51.6 3.1 1.6e-13 50.5 2.1 1.5 1 0 0 1 1 1 1 AP2 domain ParA PF10609.4 EAK89489.1 - 7e-30 102.7 0.2 1.6e-29 101.6 0.1 1.7 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EAK89489.1 - 6e-17 61.6 0.0 8.7e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EAK89489.1 - 1.5e-06 27.5 4.5 0.00021 20.4 0.3 2.6 2 1 1 3 3 3 2 Anion-transporting ATPase MipZ PF09140.6 EAK89489.1 - 5.3e-06 25.7 0.0 1.4e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 EAK89489.1 - 6e-06 26.2 0.0 1.9e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EAK89489.1 - 0.0058 15.8 0.3 0.012 14.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_26 PF13500.1 EAK89489.1 - 0.0062 16.1 0.1 0.043 13.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EAK89489.1 - 0.013 14.3 1.4 0.022 13.6 0.3 1.8 1 1 1 2 2 2 0 NB-ARC domain Fer4_NifH PF00142.13 EAK89489.1 - 0.044 12.9 0.3 0.94 8.5 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EAK89489.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.15 EAK89489.1 - 0.082 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.1 EAK89489.1 - 0.088 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EAK89489.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 NTPase RNase_H2_suC PF08615.6 EAK89490.1 - 3.1e-13 49.7 1.6 3.9e-12 46.1 1.1 1.9 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Condensin2nSMC PF12422.3 EAK89491.1 - 4.6e-44 149.8 1.6 1.1e-43 148.6 0.2 2.4 2 0 0 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.17 EAK89491.1 - 6.8e-07 28.8 1.6 0.046 13.8 0.0 4.8 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.1 EAK89491.1 - 0.00061 20.0 0.1 0.25 11.6 0.0 3.5 2 1 1 3 3 3 1 HEAT repeats ERO1 PF04137.10 EAK89492.1 - 5.3e-46 157.2 4.3 2.8e-42 145.0 0.4 2.1 1 1 1 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Sec20 PF03908.8 EAK89492.1 - 2.4 7.9 6.5 1.5 8.5 2.7 2.0 2 0 0 2 2 2 0 Sec20 Peptidase_C12 PF01088.16 EAK89493.1 - 2.6e-39 134.6 0.0 3.2e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UvrD-helicase PF00580.16 EAK89494.1 - 4.8e-53 180.5 4.4 4.8e-53 180.5 3.0 2.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EAK89494.1 - 1.1e-48 166.4 19.6 1.5e-36 126.5 1.5 3.5 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EAK89494.1 - 2.1e-11 43.4 0.0 1.4e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 EAK89494.1 - 4.3e-10 39.6 0.0 1.7e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 EAK89494.1 - 5.2e-05 22.9 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EAK89494.1 - 0.037 13.5 0.1 1.4 8.4 0.0 2.9 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF3223 PF11523.3 EAK89495.1 - 6.5e-22 77.6 1.1 6.5e-22 77.6 0.8 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3223) La PF05383.12 EAK89495.1 - 1e-14 54.0 1.8 1.7e-14 53.3 0.1 2.3 3 0 0 3 3 3 1 La domain DAP3 PF10236.4 EAK89495.1 - 0.005 15.8 0.3 0.0081 15.1 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AP2 PF00847.15 EAK89496.1 - 9.6e-12 44.8 2.8 9.6e-12 44.8 1.9 1.8 2 0 0 2 2 2 1 AP2 domain Coatomer_b_Cpla PF14806.1 EAK89497.1 - 0.032 13.9 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform CDC37_C PF08564.5 EAK89497.1 - 0.045 13.5 1.9 0.16 11.8 1.3 1.9 1 0 0 1 1 1 0 Cdc37 C terminal domain ABC1 PF03109.11 EAK89498.1 - 2.4e-26 92.0 0.0 7.6e-26 90.4 0.0 1.9 2 0 0 2 2 2 1 ABC1 family DnaJ-X PF14308.1 EAK89499.1 - 3.7e-52 176.5 6.3 8e-52 175.4 4.4 1.6 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 EAK89499.1 - 2.3e-24 84.9 6.4 4.9e-24 83.8 4.4 1.6 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.6 EAK89499.1 - 9.5e-06 25.6 0.0 3.2e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain Antimicrobial_2 PF08023.7 EAK89499.1 - 0.56 10.5 3.1 3.1 8.1 1.1 2.7 2 0 0 2 2 2 0 Frog antimicrobial peptide Methyltransf_31 PF13847.1 EAK89500.1 - 3.8e-14 52.5 0.0 6.6e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAK89500.1 - 3.2e-13 49.9 0.0 5.3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAK89500.1 - 6.9e-12 45.3 0.0 9.8e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAK89500.1 - 6.7e-10 39.3 0.0 2.3e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAK89500.1 - 1.1e-07 32.4 0.0 1.6e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAK89500.1 - 4.6e-06 26.9 0.0 7.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EAK89500.1 - 1.9e-05 23.9 0.0 2.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EAK89500.1 - 4.6e-05 22.6 0.0 6.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EAK89500.1 - 9.2e-05 22.4 0.0 0.0006 19.8 0.0 2.1 2 1 0 2 2 1 1 Methyltransferase domain Pox_MCEL PF03291.11 EAK89500.1 - 0.00048 19.1 0.0 0.0006 18.7 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme MTS PF05175.9 EAK89500.1 - 0.00088 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EAK89500.1 - 0.019 14.0 0.0 0.043 12.8 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_24 PF13578.1 EAK89500.1 - 0.035 14.9 0.0 0.06 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 EAK89500.1 - 0.061 12.3 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_8 PF05148.10 EAK89500.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Kinesin PF00225.18 EAK89501.1 - 1.7e-92 309.7 7.3 2.8e-92 309.0 5.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain PhoH PF02562.11 EAK89501.1 - 0.023 13.9 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein DUF87 PF01935.12 EAK89501.1 - 9.5 5.9 11.1 10 5.8 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 eIF-1a PF01176.14 EAK89502.1 - 3.5e-30 103.2 0.1 5.8e-30 102.5 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 CBM_14 PF01607.19 EAK89503.1 - 0.17 11.8 43.3 0.25 11.2 0.6 9.3 8 2 3 11 11 11 0 Chitin binding Peritrophin-A domain cEGF PF12662.2 EAK89503.1 - 0.19 11.3 22.6 1.2 8.7 0.2 8.5 8 0 0 8 8 8 0 Complement Clr-like EGF-like PWI PF01480.12 EAK89504.1 - 1.6e-22 79.4 0.3 4e-22 78.1 0.2 1.7 1 0 0 1 1 1 1 PWI domain U1snRNP70_N PF12220.3 EAK89504.1 - 0.31 11.4 3.3 14 6.0 0.1 2.8 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Racemase_4 PF13615.1 EAK89505.1 - 1.5e-24 86.1 0.0 3.9e-24 84.8 0.0 1.8 1 0 0 1 1 1 1 Putative alanine racemase NUC173 PF08161.7 EAK89506.1 - 4.1e-28 98.0 2.7 6.1e-27 94.2 0.0 3.8 5 0 0 5 5 5 1 NUC173 domain HEAT PF02985.17 EAK89506.1 - 0.069 13.2 0.7 21 5.5 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat Brix PF04427.13 EAK89507.1 - 7e-45 153.0 0.0 1e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain NIF PF03031.13 EAK89508.1 - 4.5e-27 94.6 0.0 1.1e-26 93.3 0.0 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DUF1313 PF07011.6 EAK89508.1 - 0.042 13.5 0.2 0.099 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1313) DUF3458 PF11940.3 EAK89509.1 - 2.1e-74 250.5 0.0 2.8e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 EAK89509.1 - 7.6e-52 176.6 0.0 1.1e-51 176.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 EAK89509.1 - 1.5e-14 54.1 0.0 2.9e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Ribosomal_L22 PF00237.14 EAK89510.1 - 1.3e-28 98.9 0.0 1.8e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e zf-RING_2 PF13639.1 EAK89511.1 - 4.2e-13 48.8 8.6 9e-13 47.8 5.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAK89511.1 - 3.3e-10 39.9 5.0 7.8e-10 38.7 3.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EAK89511.1 - 3.5e-07 30.1 9.1 3.5e-07 30.1 6.3 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK89511.1 - 1.9e-06 27.4 6.2 1.9e-06 27.4 4.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAK89511.1 - 3.5e-06 26.5 5.8 3.5e-06 26.5 4.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAK89511.1 - 1.1e-05 24.9 7.9 2.2e-05 23.9 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EAK89511.1 - 0.039 13.4 4.1 0.11 12.0 2.8 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EAK89511.1 - 0.045 13.6 4.2 0.14 11.9 2.9 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4206 PF13901.1 EAK89511.1 - 0.09 12.3 6.8 0.57 9.6 2.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4206) C1_1 PF00130.17 EAK89511.1 - 0.17 11.6 5.5 0.071 12.8 1.8 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.2 EAK89511.1 - 0.19 11.8 6.3 0.4 10.7 4.3 1.6 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 EAK89511.1 - 0.2 11.3 6.6 0.4 10.3 4.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.1 EAK89511.1 - 1.1 9.0 5.1 3.7 7.3 3.5 2.0 1 0 0 1 1 1 0 RING-type zinc-finger DUF342 PF03961.8 EAK89514.1 - 0.37 9.1 2.1 0.65 8.3 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) KSHV_K8 PF07188.6 EAK89516.1 - 0.046 12.9 0.3 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein Gate PF07670.9 EAK89517.1 - 0.29 11.0 1.3 0.98 9.3 0.9 1.9 1 1 0 1 1 1 0 Nucleoside recognition BAR PF03114.13 EAK89520.1 - 0.06 12.8 9.7 0.024 14.1 4.3 1.8 2 0 0 2 2 2 0 BAR domain DUF4337 PF14235.1 EAK89520.1 - 0.08 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF106 PF01956.11 EAK89520.1 - 0.083 12.4 0.6 0.24 10.8 0.1 1.9 2 0 0 2 2 2 0 Integral membrane protein DUF106 GAGA_bind PF06217.7 EAK89520.1 - 0.23 11.4 6.0 0.31 10.9 4.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family AAA_11 PF13086.1 EAK89520.1 - 7 6.1 8.5 11 5.5 5.9 1.4 1 1 0 1 1 1 0 AAA domain Peptidase_S49_N PF08496.5 EAK89520.1 - 7.5 6.3 9.6 18 5.1 6.7 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PSI_PsaF PF02507.10 EAK89521.1 - 8.8 5.8 6.9 0.36 10.3 0.1 2.1 3 0 0 3 3 3 0 Photosystem I reaction centre subunit III Patched PF02460.13 EAK89524.1 - 1.4e-23 82.7 27.7 2.6e-12 45.5 11.6 3.7 3 1 0 3 3 3 3 Patched family Sterol-sensing PF12349.3 EAK89524.1 - 3.6e-10 39.5 0.8 3.6e-10 39.5 0.6 3.6 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation DIM1 PF02966.11 EAK89526.1 - 1.5e-65 218.6 0.7 1.7e-65 218.5 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EAK89526.1 - 0.03 13.9 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin NuA4 PF09340.5 EAK89527.1 - 0.16 11.5 4.6 0.039 13.5 0.7 2.0 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 ER PF01133.12 EAK89529.1 - 0.0019 17.8 5.7 0.099 12.3 0.7 2.5 1 1 1 2 2 2 2 Enhancer of rudimentary DUF1128 PF06569.6 EAK89529.1 - 0.051 13.3 1.8 0.11 12.1 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) DUF1687 PF07955.6 EAK89529.1 - 3.4 7.6 7.2 29 4.6 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1687) zf-CCHC_2 PF13696.1 EAK89530.1 - 3.2e-07 29.7 0.3 6.8e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-RING_2 PF13639.1 EAK89530.1 - 8e-05 22.3 8.8 0.00017 21.3 6.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAK89530.1 - 9.5e-05 22.3 10.3 9.5e-05 22.3 7.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAK89530.1 - 0.0013 18.3 7.1 0.0013 18.3 4.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAK89530.1 - 0.03 14.2 8.7 0.21 11.4 6.3 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING GET2 PF08690.5 EAK89530.1 - 0.27 10.4 5.8 0.4 9.8 4.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 FANCL_C PF11793.3 EAK89530.1 - 0.46 10.4 5.5 1.3 9.0 3.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.1 EAK89530.1 - 0.66 9.7 16.9 0.031 13.9 6.3 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_6 PF14835.1 EAK89530.1 - 6.3 6.6 8.2 1.6e+02 2.1 5.7 2.3 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Aa_trans PF01490.13 EAK89531.1 - 2.2e-52 177.9 43.3 2.7e-52 177.6 30.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EAK89531.1 - 0.013 14.3 39.2 0.076 11.8 26.8 1.9 1 1 0 1 1 1 0 Tryptophan/tyrosine permease family SNARE PF05739.14 EAK89534.1 - 0.0002 20.9 3.0 0.00032 20.3 2.1 1.3 1 0 0 1 1 1 1 SNARE domain EMP24_GP25L PF01105.19 EAK89534.1 - 0.22 11.2 3.1 0.38 10.4 2.1 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4041 PF13250.1 EAK89534.1 - 2.3 7.8 5.8 3.5 7.2 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) CRAL_TRIO PF00650.15 EAK89535.1 - 5e-30 104.0 0.1 6.8e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EAK89535.1 - 3e-07 30.4 0.1 5.3e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain IQ PF00612.22 EAK89535.1 - 0.0067 15.9 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif AATF-Che1 PF13339.1 EAK89536.1 - 2.8e-11 43.6 0.6 6.9e-11 42.4 0.4 1.7 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor DUF2036 PF09724.4 EAK89537.1 - 1e-24 87.3 7.7 2.1e-21 76.4 5.3 3.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DUF2803 PF10972.3 EAK89537.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) DUF4097 PF13349.1 EAK89538.1 - 0.015 14.8 0.6 0.015 14.8 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) DUF4448 PF14610.1 EAK89538.1 - 0.03 13.8 0.2 0.04 13.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) UCH_1 PF13423.1 EAK89538.1 - 0.031 13.7 0.1 0.037 13.4 0.0 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF4546 PF15079.1 EAK89539.1 - 0.013 14.6 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) MU117 PF15474.1 EAK89539.1 - 0.034 14.6 2.3 5.7 7.4 0.1 2.3 2 0 0 2 2 2 0 Meiotically up-regulated gene family GOLGA2L5 PF15070.1 EAK89539.1 - 0.038 12.4 0.2 0.061 11.8 0.1 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 ING PF12998.2 EAK89539.1 - 0.12 12.6 4.6 0.18 12.1 1.3 2.3 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding YbaB_DNA_bd PF02575.11 EAK89540.1 - 0.12 12.2 0.2 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family Patatin PF01734.17 EAK89541.1 - 1.4e-07 31.6 0.0 0.00014 21.8 0.0 2.5 2 0 0 2 2 2 2 Patatin-like phospholipase Patatin PF01734.17 EAK89542.1 - 3.4e-23 82.6 0.2 1.2e-22 80.8 0.2 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase Kunitz_BPTI PF00014.18 EAK89542.1 - 0.3 11.3 1.4 12 6.2 0.0 2.8 2 1 0 2 2 2 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Aa_trans PF01490.13 EAK89543.1 - 8.9e-11 40.8 46.4 2e-06 26.5 21.2 2.3 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein ATP-synt_S1 PF05827.7 EAK89543.1 - 0.11 11.7 2.6 0.11 11.8 0.3 1.9 2 0 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) MFS_1 PF07690.11 EAK89544.1 - 2.4e-44 151.4 29.4 4.6e-43 147.2 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MMR_HSR1 PF01926.18 EAK89546.1 - 3.3e-09 36.7 0.2 1.4e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAK89546.1 - 3.6e-09 36.6 0.1 2.3e-07 30.8 0.1 2.7 1 1 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.22 EAK89546.1 - 9.6e-08 31.6 0.0 2.1e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.13 EAK89546.1 - 0.002 17.2 0.1 0.002 17.2 0.1 2.0 2 1 0 2 2 2 1 Septin ABC_tran PF00005.22 EAK89546.1 - 0.0023 18.2 1.3 0.0052 17.0 0.6 2.0 1 1 0 1 1 1 1 ABC transporter SRPRB PF09439.5 EAK89546.1 - 0.0027 16.9 0.2 0.0076 15.4 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EAK89546.1 - 0.0029 16.8 0.1 0.0029 16.8 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function, DUF258 Miro PF08477.8 EAK89546.1 - 0.0038 17.7 0.1 0.017 15.6 0.0 2.2 2 0 0 2 2 1 1 Miro-like protein FeoB_N PF02421.13 EAK89546.1 - 0.028 13.6 0.3 0.65 9.2 0.1 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EAK89546.1 - 0.03 13.8 3.7 0.3 10.5 0.1 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.11 EAK89546.1 - 0.038 13.0 4.9 0.44 9.6 0.0 2.9 3 0 0 3 3 3 0 AIG1 family AAA_29 PF13555.1 EAK89546.1 - 0.1 12.1 0.1 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTP_transferase PF00483.18 EAK89547.1 - 3.1e-13 49.5 0.0 1.1e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EAK89547.1 - 5.9e-11 41.3 7.8 6.5e-06 25.4 0.8 3.0 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EAK89547.1 - 2.6e-06 27.6 0.0 5e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EAK89547.1 - 0.0059 16.1 14.4 5.1 6.7 8.3 3.7 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EAK89547.1 - 0.14 10.7 0.8 0.24 9.9 0.5 1.3 1 0 0 1 1 1 0 L-fucokinase Seryl_tRNA_N PF02403.17 EAK89548.1 - 0.017 15.1 1.5 0.025 14.6 1.1 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.13 EAK89549.1 - 0.016 14.8 3.1 1.2 8.8 0.1 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Herpes_BLRF2 PF05812.7 EAK89549.1 - 0.028 14.2 2.0 1.2 8.9 0.2 2.6 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 EAK89549.1 - 0.04 13.8 5.0 2.7 7.9 0.1 3.2 3 0 0 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 EAK89549.1 - 0.06 13.6 8.0 1.2 9.5 0.2 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF972) Rab5-bind PF09311.6 EAK89549.1 - 0.16 11.8 3.3 0.59 9.9 0.2 2.5 1 1 1 2 2 2 0 Rabaptin-like protein DUF1875 PF08961.5 EAK89549.1 - 0.31 10.3 2.8 3.1 7.0 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) DivIVA PF05103.8 EAK89549.1 - 0.41 10.7 4.4 0.82 9.7 0.1 2.7 3 0 0 3 3 3 0 DivIVA protein DUF904 PF06005.7 EAK89549.1 - 1.1 9.5 9.7 47 4.3 3.7 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 EAK89549.1 - 1.8 8.4 8.1 9.2 6.1 0.3 3.4 4 0 0 4 4 4 0 Basic region leucine zipper cNMP_binding PF00027.24 EAK89550.1 - 3.8e-19 68.2 0.8 0.0003 20.5 0.0 5.4 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain tRNA-synt_His PF13393.1 EAK89551.1 - 4.6e-47 160.5 0.0 6.9e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EAK89551.1 - 3.4e-18 65.8 0.0 6.6e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EAK89551.1 - 7.8e-12 44.9 0.0 2.4e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EAK89551.1 - 1.4e-05 24.0 0.1 0.0016 17.2 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EAK89551.1 - 0.051 12.7 0.0 0.13 11.3 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Filamin PF00630.14 EAK89552.1 - 1.6e-31 108.8 1.4 1.5e-24 86.4 0.0 4.6 4 0 0 4 4 4 3 Filamin/ABP280 repeat WD40 PF00400.27 EAK89554.1 - 1.4e-16 59.5 7.7 2.2e-06 27.3 0.2 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Myb_DNA-bind_6 PF13921.1 EAK89555.1 - 0.00012 22.1 4.2 0.00013 21.9 1.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAK89555.1 - 0.011 15.7 0.0 0.06 13.4 0.0 2.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain PspB PF06667.7 EAK89556.1 - 0.71 9.8 5.2 1.1 9.2 0.3 2.6 2 0 0 2 2 2 0 Phage shock protein B HA2 PF04408.18 EAK89557.1 - 3.6e-26 91.1 0.1 8.1e-26 90.0 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EAK89557.1 - 3.7e-26 91.2 0.1 6.8e-26 90.3 0.1 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EAK89557.1 - 1.4e-11 44.1 0.0 3e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAK89557.1 - 4.1e-09 36.1 0.5 8.5e-09 35.1 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAK89557.1 - 6.9e-05 22.9 0.2 0.00023 21.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EAK89557.1 - 0.00018 21.3 0.3 0.087 12.6 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit UPF0079 PF02367.12 EAK89557.1 - 0.0041 16.7 0.0 0.0097 15.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 EAK89557.1 - 0.0072 15.7 0.1 0.018 14.4 0.0 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Pox_A32 PF04665.7 EAK89557.1 - 0.028 13.7 0.6 5.6 6.1 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.7 EAK89557.1 - 0.028 13.5 0.0 0.073 12.1 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin T2SE PF00437.15 EAK89557.1 - 0.043 12.7 0.0 0.091 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EAK89557.1 - 0.044 13.0 0.1 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 EAK89557.1 - 0.053 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 EAK89557.1 - 0.069 12.5 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EAK89557.1 - 0.092 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EAK89557.1 - 0.12 12.6 0.4 0.34 11.2 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_23 PF13476.1 EAK89557.1 - 0.13 12.5 5.5 0.25 11.6 0.6 2.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EAK89557.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RasGEF_N PF00618.15 EAK89557.1 - 0.28 11.3 3.0 0.66 10.0 0.6 2.5 1 1 1 2 2 2 0 RasGEF N-terminal motif Patatin PF01734.17 EAK89558.1 - 1.3e-19 70.9 0.5 1.9e-18 67.1 0.3 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase ELM2 PF01448.19 EAK89559.1 - 5e-07 30.2 0.0 8.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 ELM2 domain Dsh_C PF12316.3 EAK89559.1 - 1.1 9.2 14.5 1.3 9.0 10.0 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CBF PF03914.12 EAK89562.1 - 1.3e-24 86.5 16.7 1.1e-23 83.4 9.4 3.6 2 1 0 2 2 2 1 CBF/Mak21 family DASH_Dad3 PF08656.5 EAK89563.1 - 0.028 14.1 2.2 0.04 13.5 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF3782 PF12644.2 EAK89563.1 - 0.048 13.4 0.1 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) GMC_oxred_N PF00732.14 EAK89565.1 - 7.6e-11 41.6 0.0 4.8e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAK89565.1 - 8.1e-09 35.9 0.0 3e-05 24.3 0.0 2.7 2 0 0 2 2 2 2 GMC oxidoreductase NAD_binding_9 PF13454.1 EAK89565.1 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 EAK89565.1 - 0.0082 15.0 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAK89565.1 - 0.044 13.8 0.1 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EAK89566.1 - 4.4e-15 55.6 2.3 1e-14 54.5 1.4 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAK89566.1 - 2.4e-11 43.8 1.6 4e-11 43.1 1.1 1.4 1 0 0 1 1 1 1 HMG-box domain DUF2398 PF09661.5 EAK89566.1 - 0.13 11.0 0.2 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) CPSF_A PF03178.10 EAK89567.1 - 1.2e-76 257.8 1.4 2e-73 247.2 0.2 3.2 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.4 EAK89567.1 - 4.9e-57 193.2 0.3 1e-56 192.1 0.2 1.6 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Rad60-SLD PF11976.3 EAK89568.1 - 9e-24 82.9 0.0 1.4e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EAK89568.1 - 9.6e-08 31.3 0.0 1.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBX PF00789.15 EAK89568.1 - 0.013 15.5 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 UBX domain PTB PF08416.8 EAK89568.1 - 0.066 13.1 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotyrosine-binding domain PH PF00169.24 EAK89569.1 - 0.00043 20.4 0.0 0.00065 19.8 0.0 1.3 1 0 0 1 1 1 1 PH domain DUF3972 PF13118.1 EAK89569.1 - 0.016 15.2 0.1 3.4 7.7 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) DUF2393 PF09624.5 EAK89571.1 - 0.75 9.3 3.6 6.1 6.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Fibrillarin PF01269.12 EAK89572.1 - 2.9e-111 369.9 0.0 3.4e-111 369.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EAK89572.1 - 4.4e-05 23.1 0.0 6.1e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EAK89572.1 - 0.0051 16.3 0.0 0.0073 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EAK89572.1 - 0.051 12.4 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase PCMT PF01135.14 EAK89572.1 - 0.09 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UCH PF00443.24 EAK89573.1 - 9.9e-49 165.8 6.5 9.9e-49 165.8 4.5 2.7 2 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAK89573.1 - 3e-28 99.1 3.9 3e-28 99.1 2.7 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RAG2_PHD PF13341.1 EAK89573.1 - 0.22 11.5 4.2 8.7 6.4 1.2 2.9 2 0 0 2 2 2 0 RAG2 PHD domain zf-HIT PF04438.11 EAK89573.1 - 6.5 6.5 8.5 1.9 8.1 0.4 3.2 3 0 0 3 3 3 0 HIT zinc finger Ribosomal_L30 PF00327.15 EAK89574.1 - 2.5e-18 65.3 1.0 2.5e-18 65.3 0.7 2.2 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 EAK89574.1 - 4.4e-14 52.2 4.6 7.7e-14 51.4 3.2 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Nop14 PF04147.7 EAK89575.1 - 3.2e-57 194.1 67.6 1.2e-47 162.4 39.4 2.4 2 1 0 2 2 2 2 Nop14-like family SKIP_SNW PF02731.10 EAK89576.1 - 8.9e-57 190.9 5.3 8.9e-57 190.9 3.6 2.6 2 1 1 3 3 3 1 SKIP/SNW domain TFIIS_M PF07500.9 EAK89578.1 - 9e-30 103.0 1.5 9e-30 103.0 1.0 2.7 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EAK89578.1 - 7.1e-20 70.3 5.8 1.4e-19 69.4 4.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EAK89578.1 - 1.2e-13 50.2 1.2 1.2e-13 50.2 0.9 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Elf1 PF05129.8 EAK89578.1 - 0.063 12.9 2.4 0.18 11.4 1.7 1.9 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 EAK89578.1 - 0.23 11.0 3.4 3.3 7.3 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EAK89578.1 - 0.5 10.0 3.3 6.1 6.6 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EAK89578.1 - 0.7 9.2 2.9 5.4 6.4 2.2 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding LOH1CR12 PF10158.4 EAK89578.1 - 0.94 9.2 9.3 2.7 7.7 1.4 2.6 3 0 0 3 3 3 0 Tumour suppressor protein zf-RING_2 PF13639.1 EAK89580.1 - 0.031 14.1 5.3 0.074 12.9 3.6 1.7 1 0 0 1 1 1 0 Ring finger domain Tn7_Tnp_TnsA_N PF08722.6 EAK89580.1 - 0.048 13.6 0.1 0.19 11.7 0.0 2.0 1 0 0 1 1 1 0 TnsA endonuclease N terminal eIF-5_eIF-2B PF01873.12 EAK89581.1 - 1.6e-35 121.4 0.0 4.9e-35 119.9 0.0 1.7 1 1 1 2 2 2 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EAK89581.1 - 0.0052 17.0 0.2 0.0092 16.2 0.1 1.4 1 0 0 1 1 1 1 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.7 EAK89581.1 - 0.13 11.5 0.2 0.24 10.7 0.2 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_6 PF14599.1 EAK89581.1 - 0.34 10.7 1.8 8.9 6.1 0.2 2.3 1 1 1 2 2 2 0 Zinc-ribbon Elf1 PF05129.8 EAK89581.1 - 3.2 7.5 5.9 0.68 9.6 0.2 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Acyl_transf_3 PF01757.17 EAK89582.1 - 2.4e-61 207.4 20.9 2.4e-61 207.4 14.5 2.1 1 1 1 2 2 2 1 Acyltransferase family DUF4551 PF15087.1 EAK89584.1 - 0.025 12.9 8.9 0.036 12.4 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PI3_PI4_kinase PF00454.22 EAK89585.1 - 2.2e-24 86.2 0.5 1.9e-23 83.1 0.4 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NYD-SP28 PF14772.1 EAK89588.1 - 0.014 15.4 1.3 0.047 13.7 0.9 1.9 1 0 0 1 1 1 0 Sperm tail DUF972 PF06156.8 EAK89589.1 - 0.0002 21.6 45.0 0.0031 17.8 6.0 5.2 3 1 2 5 5 5 3 Protein of unknown function (DUF972) SseC PF04888.7 EAK89589.1 - 0.0035 16.7 9.8 0.0035 16.7 6.8 2.9 3 0 0 3 3 3 1 Secretion system effector C (SseC) like family KLRAQ PF10205.4 EAK89589.1 - 0.0038 17.2 11.6 0.0038 17.2 8.1 4.2 3 2 3 6 6 6 1 Predicted coiled-coil domain-containing protein BLOC1_2 PF10046.4 EAK89589.1 - 0.0055 16.8 2.2 0.0055 16.8 1.5 4.9 2 1 3 5 5 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.1 EAK89589.1 - 0.0074 16.7 17.2 0.014 15.8 0.0 4.7 3 1 2 5 5 5 1 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.16 EAK89589.1 - 0.02 14.8 2.9 0.02 14.8 2.0 4.9 4 1 0 4 4 4 0 bZIP transcription factor HALZ PF02183.13 EAK89589.1 - 0.2 11.3 28.2 0.12 12.0 3.9 5.0 4 2 1 5 5 5 0 Homeobox associated leucine zipper CCDC155 PF14662.1 EAK89589.1 - 0.34 10.4 49.1 0.02 14.4 24.9 3.0 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 ADIP PF11559.3 EAK89589.1 - 0.67 9.8 52.1 0.44 10.4 8.5 4.3 3 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EAK89589.1 - 1.2 8.2 18.5 0.024 13.8 2.2 3.4 2 2 1 3 3 3 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EAK89589.1 - 1.7 8.5 49.4 0.05 13.4 6.9 4.8 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EAK89589.1 - 3 5.4 44.5 1.4 6.5 0.2 2.8 2 1 0 2 2 2 0 Myosin tail DASH_Hsk3 PF08227.6 EAK89589.1 - 3.3 7.9 11.4 3.5 7.8 0.3 3.5 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like MxiH PF09392.5 EAK89589.1 - 7.3 7.2 10.9 2.8e+02 2.1 7.0 3.3 2 1 0 2 2 1 0 Type III secretion needle MxiH like Tox-REase-2 PF15646.1 EAK89590.1 - 0.77 9.6 4.2 0.59 10.0 1.6 1.8 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 2 Ribonuc_2-5A PF06479.7 EAK89590.1 - 1.7 8.4 10.2 0.17 11.7 1.9 2.5 1 1 1 2 2 2 0 Ribonuclease 2-5A DUF2053 PF09767.4 EAK89591.1 - 3.9e-12 46.4 6.0 4.8e-12 46.1 4.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) DUF3938 PF13074.1 EAK89591.1 - 0.2 11.5 2.6 0.27 11.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3938) GCN5L1 PF06320.8 EAK89594.1 - 0.046 13.5 4.5 2.9 7.7 0.1 2.8 1 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) Snapin_Pallidin PF14712.1 EAK89594.1 - 0.075 13.3 4.2 1.3 9.4 0.1 3.2 3 0 0 3 3 3 0 Snapin/Pallidin DUF16 PF01519.11 EAK89594.1 - 0.086 13.0 6.9 0.6 10.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF869 PF05911.6 EAK89594.1 - 0.089 11.0 7.0 0.11 10.7 4.8 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF2524 PF10732.4 EAK89594.1 - 0.17 12.0 3.6 1.3 9.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) Med2 PF11214.3 EAK89594.1 - 0.39 10.7 4.8 0.11 12.5 0.9 2.0 2 1 0 2 2 2 0 Mediator complex subunit 2 Baculo_PEP_C PF04513.7 EAK89594.1 - 0.4 10.5 7.9 0.2 11.4 1.3 2.6 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 EAK89594.1 - 1.1 9.3 11.6 1.2 9.2 3.1 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family PspB PF06667.7 EAK89594.1 - 2.2 8.2 4.7 2.7 7.9 0.1 3.0 3 1 0 3 3 3 0 Phage shock protein B NUDIX PF00293.23 EAK89595.1 - 6.9e-07 28.9 0.0 9.3e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Atrophin-1 PF03154.10 EAK89596.1 - 1.2 7.1 5.4 1.6 6.7 3.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family Nucleoside_tran PF01733.13 EAK89596.1 - 1.2 8.2 3.8 2.8 7.0 2.7 1.6 1 0 0 1 1 1 0 Nucleoside transporter OmpH PF03938.9 EAK89596.1 - 3.9 7.3 21.2 1.4 8.8 11.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SNF2_N PF00176.18 EAK89597.1 - 1.7e-52 178.1 0.0 9.9e-52 175.5 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain PHD PF00628.24 EAK89597.1 - 4.8e-21 74.1 69.2 1.4e-10 40.7 3.9 6.5 6 0 0 6 6 6 5 PHD-finger Helicase_C PF00271.26 EAK89597.1 - 5.2e-10 39.0 0.0 1.8e-09 37.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD_2 PF13831.1 EAK89597.1 - 0.00028 20.1 1.0 0.00028 20.1 0.7 6.9 7 0 0 7 7 7 2 PHD-finger ELO PF01151.13 EAK89598.1 - 6.5e-67 225.4 25.1 8.3e-67 225.0 17.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family WD40 PF00400.27 EAK89599.1 - 0.00025 20.7 3.2 27 4.8 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat DNA_pol_delta_4 PF04081.8 EAK89600.1 - 3.1e-07 30.7 0.0 4.4e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 MRP-L27 PF09809.4 EAK89600.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 HAS-barrel PF09378.5 EAK89602.1 - 0.025 14.4 2.2 1.5 8.7 0.2 2.5 1 1 1 2 2 2 0 HAS barrel domain Brix PF04427.13 EAK89603.1 - 2.4e-30 105.6 0.5 3.2e-30 105.2 0.4 1.1 1 0 0 1 1 1 1 Brix domain Sec23_trunk PF04811.10 EAK89603.1 - 0.093 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain LepA_C PF06421.7 EAK89604.1 - 0.026 14.4 0.9 0.056 13.3 0.6 1.5 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus tRNA-synt_2b PF00587.20 EAK89605.1 - 3.5e-33 114.6 0.1 8.5e-33 113.3 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EAK89605.1 - 4.5e-14 52.3 9.0 1e-13 51.2 6.2 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain zf-DHHC PF01529.15 EAK89606.1 - 7.5e-29 100.3 14.9 7.5e-29 100.3 10.3 2.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase PSI PF01437.20 EAK89606.1 - 3.4 7.9 13.3 2.2 8.4 7.4 2.1 1 1 0 1 1 1 0 Plexin repeat DEAD PF00270.24 EAK89607.1 - 5e-31 107.4 0.1 1.3e-30 106.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK89607.1 - 5e-21 74.3 0.4 1.1e-20 73.3 0.3 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EAK89607.1 - 0.0088 16.1 0.0 0.11 12.6 0.0 2.5 1 1 1 2 2 2 1 AAA domain Methyltransf_31 PF13847.1 EAK89608.1 - 3.1e-11 43.0 0.1 5.7e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAK89608.1 - 1.5e-09 37.3 0.1 2.7e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EAK89608.1 - 3e-09 37.4 0.0 6.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAK89608.1 - 1.1e-08 35.1 0.0 2.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAK89608.1 - 2.2e-06 28.0 0.0 4.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EAK89608.1 - 3.4e-05 22.7 0.1 4.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EAK89608.1 - 4.3e-05 22.9 0.1 7.3e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.11 EAK89608.1 - 0.0002 20.4 0.5 0.00025 20.0 0.3 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 EAK89608.1 - 0.00026 20.7 0.0 0.00044 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EAK89608.1 - 0.00074 19.0 0.1 0.0012 18.3 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EAK89608.1 - 0.00086 19.6 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EAK89608.1 - 0.0039 16.7 0.1 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 EAK89608.1 - 0.0051 16.1 0.1 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 EAK89608.1 - 0.0094 16.4 0.0 0.028 14.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain UPF0020 PF01170.13 EAK89608.1 - 0.036 13.6 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.12 EAK89608.1 - 0.036 13.0 0.1 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Rsm22 PF09243.5 EAK89608.1 - 0.044 12.8 0.0 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 CMAS PF02353.15 EAK89608.1 - 0.049 12.6 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 EAK89608.1 - 0.053 14.3 0.0 0.1 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EAK89608.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 Conserved hypothetical protein 95 GidB PF02527.10 EAK89608.1 - 0.095 11.8 0.2 0.19 10.8 0.1 1.6 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G CPSF_A PF03178.10 EAK89609.1 - 1.3e-18 67.2 0.2 2e-14 53.4 0.0 3.0 3 0 0 3 3 3 2 CPSF A subunit region RIC1 PF07064.8 EAK89610.1 - 2.1e-05 24.1 0.6 6.3e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 RIC1 ATP-synt_C PF00137.16 EAK89611.1 - 3e-32 110.3 17.0 1.6e-18 66.3 2.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SHMT PF00464.14 EAK89612.1 - 2.6e-74 249.9 0.0 1.4e-73 247.5 0.0 1.8 1 1 0 1 1 1 1 Serine hydroxymethyltransferase RecO_N_2 PF13114.1 EAK89612.1 - 0.011 15.4 0.2 0.046 13.4 0.0 2.1 2 0 0 2 2 2 0 RecO N terminal RINGv PF12906.2 EAK89613.1 - 5.3e-13 48.7 6.9 1.3e-12 47.5 4.8 1.8 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.21 EAK89613.1 - 2.9e-12 46.5 1.6 2.8e-11 43.3 0.2 3.0 3 0 0 3 3 3 1 FHA domain zf-RING_2 PF13639.1 EAK89613.1 - 0.0063 16.3 6.4 0.016 15.0 4.5 1.8 1 0 0 1 1 1 1 Ring finger domain NIF PF03031.13 EAK89614.1 - 1.4e-16 60.5 5.0 4.1e-12 46.0 0.2 3.2 1 1 2 3 3 3 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EAK89614.1 - 2.9e-07 30.2 0.0 6.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain PNK3P PF08645.6 EAK89614.1 - 0.0033 16.8 0.1 0.16 11.4 0.0 2.5 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase BRCT PF00533.21 EAK89614.1 - 0.0051 16.9 3.1 0.0063 16.6 0.3 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain HAD_2 PF13419.1 EAK89614.1 - 0.014 15.6 0.0 0.057 13.6 0.0 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TFIID-31kDa PF02291.10 EAK89615.1 - 0.0022 17.7 0.1 0.57 9.9 0.1 2.1 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Kazal_1 PF00050.16 EAK89616.1 - 5.3e-08 32.7 3.1 9.6e-08 31.9 2.2 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EAK89616.1 - 2.4e-07 30.5 1.9 4.8e-07 29.5 1.3 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Hamartin PF04388.7 EAK89616.1 - 0.12 10.9 17.7 0.14 10.7 12.3 1.2 1 0 0 1 1 1 0 Hamartin protein DUF966 PF06136.8 EAK89616.1 - 6.2 6.1 16.6 11 5.3 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RNA_pol_Rpc4 PF05132.9 EAK89616.1 - 8.8 6.3 9.1 4.8 7.1 2.2 2.3 1 1 1 2 2 2 0 RNA polymerase III RPC4 Sporozoite_P67 PF05642.6 EAK89617.1 - 0.00046 18.1 15.7 0.00046 18.1 10.9 5.4 3 2 1 4 4 4 1 Sporozoite P67 surface antigen Myb_DNA-binding PF00249.26 EAK89617.1 - 0.0005 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sad1_UNC PF07738.8 EAK89618.1 - 1.4e-10 41.1 4.0 2.2e-07 30.7 0.0 3.1 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal DUF948 PF06103.6 EAK89618.1 - 0.074 12.9 1.0 0.41 10.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SelP_N PF04592.9 EAK89619.1 - 1.5 8.1 18.5 2.5 7.4 12.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Neur_chan_memb PF02932.11 EAK89619.1 - 6 6.6 6.1 10 5.9 4.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RNase_T PF00929.19 EAK89620.1 - 3.6e-14 53.3 0.0 6.5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease WD40 PF00400.27 EAK89621.1 - 3e-05 23.7 4.2 0.00087 19.0 0.2 3.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Glyco_transf_20 PF00982.16 EAK89622.1 - 1.8e-102 343.3 1.7 1.1e-88 297.8 0.2 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EAK89622.1 - 1.4e-45 155.0 0.0 4.6e-29 101.0 0.0 3.1 2 1 0 2 2 2 2 Trehalose-phosphatase Helicase_C PF00271.26 EAK89623.1 - 5e-21 74.3 0.0 1.7e-19 69.4 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAK89623.1 - 1.3e-14 54.0 0.1 2.4e-13 49.9 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase eIF3_p135 PF12807.2 EAK89624.1 - 1.6e-07 31.4 0.8 1.6e-07 31.4 0.6 3.8 3 1 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 Apc3 PF12895.2 EAK89624.1 - 1.6e-05 24.9 0.2 0.0085 16.2 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 Fungal_trans_2 PF11951.3 EAK89625.1 - 0.002 16.8 0.6 0.0023 16.5 0.4 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gtr1_RagA PF04670.7 EAK89626.1 - 1e-51 175.3 0.4 1.4e-51 174.8 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EAK89626.1 - 5.8e-08 32.1 0.0 1.1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EAK89626.1 - 8.7e-05 21.8 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EAK89626.1 - 0.00036 20.4 0.0 0.00083 19.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAK89626.1 - 0.02 15.3 0.0 0.04 14.4 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein KTI12 PF08433.5 EAK89626.1 - 0.045 12.9 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Dynamin_N PF00350.18 EAK89626.1 - 0.2 11.4 2.5 15 5.3 0.2 2.9 3 1 1 4 4 4 0 Dynamin family DUF190 PF02641.10 EAK89627.1 - 0.083 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 IMCp PF12314.3 EAK89629.1 - 1.1e-19 70.3 26.5 1.1e-19 70.3 18.4 3.3 1 1 2 3 3 3 2 Inner membrane complex protein CBM_20 PF00686.14 EAK89630.1 - 4.4e-21 74.3 2.3 6.1e-21 73.8 1.6 1.1 1 0 0 1 1 1 1 Starch binding domain NRDE-2 PF08424.5 EAK89630.1 - 0.088 11.6 0.4 0.14 11.0 0.3 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference FtsK_SpoIIIE_N PF12538.3 EAK89630.1 - 0.11 12.6 0.2 0.28 11.3 0.0 1.8 1 1 1 2 2 2 0 DNA transporter DUF727 PF05303.7 EAK89631.1 - 0.1 12.4 0.1 1.2 9.0 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF727) SIC PF03482.8 EAK89632.1 - 0.071 12.7 1.2 0.087 12.4 0.8 1.2 1 0 0 1 1 1 0 sic protein DUF4064 PF13273.1 EAK89633.1 - 0.059 13.4 0.8 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) CemA PF03040.9 EAK89633.1 - 0.24 10.9 3.8 2.3 7.7 0.0 2.7 3 0 0 3 3 3 0 CemA family DUF912 PF06024.7 EAK89633.1 - 1 9.4 5.2 3.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) IL2 PF00715.12 EAK89634.1 - 0.12 12.1 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Interleukin 2 AP-5_subunit_s1 PF15001.1 EAK89635.1 - 0.01 15.7 0.2 0.014 15.3 0.2 1.3 1 1 0 1 1 1 0 AP-5 complex subunit sigma-1 HAUS-augmin3 PF14932.1 EAK89636.1 - 0.013 14.7 2.8 0.015 14.4 1.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 MHC_I PF00129.13 EAK89636.1 - 0.035 13.4 0.6 0.056 12.7 0.4 1.3 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 DUF1878 PF08963.5 EAK89636.1 - 0.17 12.1 2.1 0.28 11.4 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) DUF2935 PF11155.3 EAK89636.1 - 0.45 10.6 2.7 0.72 9.9 1.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) bZIP_1 PF00170.16 EAK89636.1 - 0.57 10.1 8.4 1 9.3 2.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF2205 PF10224.4 EAK89636.1 - 0.6 9.7 5.7 0.24 11.0 1.8 1.9 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) RNB PF00773.14 EAK89637.1 - 2.2e-99 332.8 7.5 2.2e-99 332.8 5.2 2.8 2 0 0 2 2 2 2 RNB domain OB_RNB PF08206.6 EAK89637.1 - 4.9e-06 25.9 0.1 1e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain EMP24_GP25L PF01105.19 EAK89638.1 - 7.6e-18 64.8 0.2 1.1e-17 64.3 0.1 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF148 PF02520.12 EAK89638.1 - 0.22 11.3 3.0 0.35 10.6 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 V-SNARE_C PF12352.3 EAK89639.1 - 0.036 14.1 0.4 0.15 12.1 0.2 2.0 1 1 1 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Vip3A_N PF12495.3 EAK89639.1 - 0.039 13.6 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal PRT_C PF08372.5 EAK89639.1 - 0.094 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Fib_alpha PF08702.5 EAK89639.1 - 1.5 8.9 9.7 5.5 7.1 1.4 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc24 PF08286.6 EAK89639.1 - 4 7.1 9.5 1 9.0 2.2 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 BRCA2 PF00634.13 EAK89641.1 - 8.5e-63 207.1 32.3 5.3e-08 31.9 0.1 8.7 8 0 0 8 8 8 8 BRCA2 repeat BRCA-2_OB1 PF09103.5 EAK89641.1 - 6.3e-23 80.7 0.0 1.5e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Toxin_62 PF15540.1 EAK89641.1 - 0.029 14.4 0.4 11 6.1 0.0 4.4 3 2 2 5 5 5 0 Putative toxin 62 PAP2 PF01569.16 EAK89642.1 - 1e-09 38.1 5.7 1e-09 38.1 4.0 1.6 2 0 0 2 2 2 1 PAP2 superfamily DsbB PF02600.11 EAK89644.1 - 0.013 15.2 7.4 0.025 14.3 5.1 1.5 1 0 0 1 1 1 0 Disulfide bond formation protein DsbB Alg14 PF08660.6 EAK89644.1 - 0.016 15.1 1.5 2.8 7.9 0.0 3.0 2 2 1 3 3 3 0 Oligosaccharide biosynthesis protein Alg14 like DUF3974 PF13120.1 EAK89644.1 - 0.018 14.8 1.1 0.053 13.3 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) Histone PF00125.19 EAK89645.1 - 1.4e-14 53.9 0.5 1.7e-14 53.6 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAK89645.1 - 0.00017 21.5 0.1 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 EAK89645.1 - 0.00091 19.1 0.1 0.0012 18.7 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EAK89645.1 - 0.0051 16.9 0.2 0.0068 16.5 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TFIID-31kDa PF02291.10 EAK89645.1 - 0.0098 15.6 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 EAK89645.1 - 0.024 14.3 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated FbpA PF05833.6 EAK89645.1 - 0.07 11.6 0.0 0.082 11.4 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Thr_dehydrat_C PF00585.13 EAK89645.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase PHD PF00628.24 EAK89646.1 - 1.3e-11 44.0 36.4 8.9e-09 34.9 8.4 5.0 3 2 1 4 4 4 2 PHD-finger PHD_2 PF13831.1 EAK89646.1 - 0.0071 15.6 6.2 0.0071 15.6 4.3 6.1 5 2 1 6 6 6 2 PHD-finger SRP54 PF00448.17 EAK89647.1 - 6.6e-56 188.8 0.4 1.3e-55 187.9 0.3 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EAK89647.1 - 1.6e-07 30.9 24.2 0.00031 20.2 5.4 2.2 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal ArgK PF03308.11 EAK89647.1 - 8e-07 28.0 0.0 1.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EAK89647.1 - 1.9e-05 24.1 1.7 1.9e-05 24.1 1.2 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 EAK89647.1 - 0.00029 20.8 0.3 0.00029 20.8 0.2 2.4 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.1 EAK89647.1 - 0.0015 18.6 0.0 0.0053 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EAK89647.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAK89647.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Nuc_deoxyrib_tr PF05014.10 EAK89647.1 - 0.013 15.3 0.3 0.064 13.1 0.0 2.3 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase NTPase_1 PF03266.10 EAK89647.1 - 0.028 14.1 0.1 1.9 8.1 0.0 2.9 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.1 EAK89647.1 - 0.045 13.2 0.5 1.1 8.8 0.0 3.1 2 1 1 3 3 3 0 P-loop containing region of AAA domain B12-binding PF02310.14 EAK89647.1 - 0.098 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain MobB PF03205.9 EAK89647.1 - 0.12 12.1 1.1 0.46 10.1 0.1 2.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AA_permease_2 PF13520.1 EAK89648.1 - 5.5e-12 44.9 41.1 8.8e-12 44.2 28.2 1.4 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 EAK89651.1 - 6.9e-12 45.0 0.1 1.1e-05 24.7 0.2 2.9 2 1 0 2 2 2 2 Protein kinase domain Ku PF02735.11 EAK89651.1 - 3.1e-05 23.4 0.4 0.0026 17.1 0.1 2.2 2 0 0 2 2 2 2 Ku70/Ku80 beta-barrel domain Kinase-like PF14531.1 EAK89651.1 - 0.0047 15.9 0.0 0.013 14.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.12 EAK89651.1 - 0.014 14.4 0.1 1.8 7.5 0.1 2.5 2 1 0 2 2 2 0 Protein tyrosine kinase Cnd3 PF12719.2 EAK89652.1 - 3.3 6.5 7.2 1.4 7.8 0.8 2.3 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain CENP-T PF15511.1 EAK89656.1 - 0.036 13.3 9.9 0.048 12.8 6.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 EAK89656.1 - 0.037 12.5 11.7 0.045 12.2 8.1 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EAK89656.1 - 0.053 11.4 7.7 0.061 11.2 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EAK89656.1 - 0.3 9.0 6.4 0.37 8.7 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein MDM1 PF15501.1 EAK89656.1 - 1.1 8.1 13.1 1.3 7.8 9.1 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 Hid1 PF12722.2 EAK89656.1 - 1.5 6.3 7.5 1.7 6.1 5.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CobT PF06213.7 EAK89656.1 - 6.2 5.8 22.0 10 5.1 15.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ER-remodelling PF14755.1 EAK89656.1 - 8.4 6.4 12.1 2.3e+02 1.8 8.4 2.7 1 1 0 1 1 1 0 Intracellular membrane remodeller Zip PF02535.17 EAK89658.1 - 0.00042 19.4 9.2 0.00052 19.1 6.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter SelP_N PF04592.9 EAK89658.1 - 0.027 13.8 21.9 0.037 13.4 15.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BBS1 PF14779.1 EAK89659.1 - 0.082 11.8 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 ChaB PF06150.7 EAK89662.1 - 0.084 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 ChaB BBP1_C PF15272.1 EAK89663.1 - 0.0061 16.1 1.4 0.013 15.0 0.7 1.8 1 1 0 1 1 1 1 Spindle pole body component BBP1, C-terminal SbcD_C PF12320.3 EAK89663.1 - 0.018 15.0 0.1 0.034 14.1 0.1 1.5 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain DapH_N PF08503.5 EAK89663.1 - 0.039 14.0 0.1 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal TPM PF04536.9 EAK89664.1 - 0.0097 15.7 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase AAA PF00004.24 EAK89665.1 - 5.2e-42 143.1 0.0 9.9e-42 142.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EAK89665.1 - 6.6e-07 29.3 0.3 4.7e-06 26.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EAK89665.1 - 1.2e-06 28.3 0.1 1.5e-05 24.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAK89665.1 - 2.3e-06 27.7 0.0 8.8e-05 22.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAK89665.1 - 7.5e-06 26.1 0.0 0.0012 18.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EAK89665.1 - 1.1e-05 24.6 0.0 2.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EAK89665.1 - 0.00059 19.2 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EAK89665.1 - 0.00092 18.0 0.0 0.002 16.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EAK89665.1 - 0.0012 19.7 0.2 0.005 17.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EAK89665.1 - 0.0014 17.7 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EAK89665.1 - 0.0016 17.9 0.0 0.005 16.3 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EAK89665.1 - 0.002 18.3 0.0 0.0044 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 EAK89665.1 - 0.003 16.7 0.0 0.0061 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EAK89665.1 - 0.003 17.8 0.1 0.059 13.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAK89665.1 - 0.0033 17.1 0.0 0.0083 15.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 EAK89665.1 - 0.0036 16.9 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EAK89665.1 - 0.0043 16.9 0.0 0.04 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EAK89665.1 - 0.0045 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EAK89665.1 - 0.0059 15.5 0.0 0.014 14.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.11 EAK89665.1 - 0.0088 15.3 0.5 0.017 14.3 0.0 1.6 2 0 0 2 2 1 1 PhoH-like protein AAA_25 PF13481.1 EAK89665.1 - 0.013 14.9 0.2 0.069 12.5 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 EAK89665.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EAK89665.1 - 0.015 14.8 0.1 0.028 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EAK89665.1 - 0.023 13.8 0.1 0.082 12.0 0.0 1.9 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.1 EAK89665.1 - 0.026 14.5 0.0 0.061 13.3 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EAK89665.1 - 0.027 13.3 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SKI PF01202.17 EAK89665.1 - 0.031 14.1 0.5 0.24 11.2 0.0 2.5 2 1 1 3 3 3 0 Shikimate kinase NACHT PF05729.7 EAK89665.1 - 0.033 13.8 0.1 0.24 11.0 0.0 2.3 1 1 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EAK89665.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EAK89665.1 - 0.07 13.4 0.6 6.8 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EAK89665.1 - 0.085 12.4 0.8 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 EAK89665.1 - 0.22 11.1 2.0 0.43 10.1 1.4 1.4 1 0 0 1 1 1 0 IncA protein cobW PF02492.14 EAK89666.1 - 2.1e-40 138.0 1.3 3.3e-40 137.4 0.9 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EAK89666.1 - 0.00014 22.0 0.0 0.00052 20.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EAK89666.1 - 0.00021 21.0 0.0 0.0006 19.5 0.0 1.8 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EAK89666.1 - 0.00054 19.8 0.0 0.0016 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain CobW_C PF07683.9 EAK89666.1 - 0.0011 18.6 0.0 0.0031 17.1 0.0 1.9 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.1 EAK89666.1 - 0.0029 17.6 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 EAK89666.1 - 0.005 16.3 0.3 0.015 14.8 0.0 1.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase MobB PF03205.9 EAK89666.1 - 0.007 16.0 0.0 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EAK89666.1 - 0.0092 15.4 0.4 2.3 7.6 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_19 PF13245.1 EAK89666.1 - 0.0098 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 EAK89666.1 - 0.017 15.4 1.8 0.051 13.8 1.0 2.2 1 1 0 1 1 1 0 ABC transporter T2SE PF00437.15 EAK89666.1 - 0.022 13.6 0.0 0.047 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 EAK89666.1 - 0.026 14.8 5.3 0.04 14.2 0.0 3.3 2 1 0 3 3 3 0 AAA domain NACHT PF05729.7 EAK89666.1 - 0.029 14.0 0.1 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 EAK89666.1 - 0.038 13.0 0.0 0.087 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 EAK89666.1 - 0.04 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EAK89666.1 - 0.1 12.1 0.0 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain UDPG_MGDP_dh_N PF03721.9 EAK89667.1 - 2.8e-57 193.0 0.4 5.7e-57 192.0 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EAK89667.1 - 3.7e-38 129.9 0.0 5.8e-36 122.8 0.0 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EAK89667.1 - 1.8e-28 98.5 0.0 4.7e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 EAK89667.1 - 2.7e-08 33.7 0.0 0.00055 19.7 0.0 2.7 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EAK89667.1 - 0.004 17.0 0.0 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EAK89667.1 - 0.012 15.7 0.4 0.16 12.1 0.1 3.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EAK89667.1 - 0.06 12.3 0.0 0.23 10.3 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase AAA_14 PF13173.1 EAK89667.1 - 0.1 12.4 0.7 0.51 10.2 0.0 2.5 4 0 0 4 4 4 0 AAA domain Adap_comp_sub PF00928.16 EAK89668.1 - 2.6e-55 187.3 2.2 3.8e-55 186.8 1.5 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EAK89668.1 - 3.1e-05 23.7 4.6 6.7e-05 22.6 3.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain EF-hand_6 PF13405.1 EAK89669.1 - 0.0056 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EAK89669.1 - 0.0065 16.5 0.0 0.014 15.4 0.0 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EAK89669.1 - 0.019 14.5 0.1 0.053 13.1 0.1 1.9 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_9 PF14658.1 EAK89669.1 - 0.036 13.9 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 EAK89669.1 - 0.063 12.6 0.0 0.22 10.9 0.0 1.9 2 1 1 3 3 3 0 EF hand Gar1 PF04410.9 EAK89670.1 - 5.6e-18 64.8 0.1 5.6e-18 64.8 0.1 2.3 2 1 0 2 2 2 1 Gar1/Naf1 RNA binding region ER_lumen_recept PF00810.13 EAK89671.1 - 3.3e-52 176.9 14.3 5e-52 176.2 9.9 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EAK89671.1 - 0.28 10.7 12.8 0.054 13.0 1.2 3.8 3 1 1 4 4 4 0 PQ loop repeat CTP_transf_2 PF01467.21 EAK89672.1 - 9.3e-19 68.0 0.5 2e-18 66.9 0.4 1.7 1 1 0 1 1 1 1 Cytidylyltransferase DUF1900 PF08954.6 EAK89673.1 - 8.6e-38 128.9 0.0 1.9e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 EAK89673.1 - 7.1e-19 66.9 0.3 1.8e-07 30.7 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat NPV_P10 PF05531.7 EAK89673.1 - 0.001 19.2 1.4 0.0029 17.8 0.3 2.2 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF1899 PF08953.6 EAK89673.1 - 0.0019 17.7 0.0 0.0088 15.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) YmzC PF14157.1 EAK89673.1 - 0.04 13.7 0.3 3.2 7.6 0.0 2.9 2 0 0 2 2 2 0 YmzC-like protein IncA PF04156.9 EAK89673.1 - 6.6 6.2 10.0 0.14 11.7 1.1 2.0 2 0 0 2 2 2 0 IncA protein Mito_carr PF00153.22 EAK89674.1 - 9.3e-68 224.0 2.9 1.8e-25 88.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Herpes_UL31 PF02718.9 EAK89674.1 - 0.12 11.0 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL31-like protein HALZ PF02183.13 EAK89675.1 - 0.041 13.5 8.3 0.28 10.9 0.4 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper EF-hand_1 PF00036.27 EAK89676.1 - 3.1e-29 98.0 7.9 1.1e-08 33.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EAK89676.1 - 1.7e-28 98.5 11.0 1.1e-14 54.2 1.3 2.6 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EAK89676.1 - 4.8e-24 82.0 5.4 1.9e-08 33.5 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EAK89676.1 - 4.1e-19 66.9 8.9 2.6e-07 29.6 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EAK89676.1 - 4.3e-19 67.8 9.4 3.8e-11 42.4 0.4 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 EAK89676.1 - 4e-11 42.6 0.1 4.9e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EAK89676.1 - 3.9e-05 23.3 2.4 0.065 12.9 0.1 3.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 EAK89676.1 - 5.1e-05 23.0 0.1 0.011 15.4 0.0 2.8 2 1 1 3 3 3 1 Tellurite resistance protein TerB Caleosin PF05042.8 EAK89676.1 - 0.0023 17.5 0.1 0.072 12.6 0.0 2.5 2 1 1 3 3 3 1 Caleosin related protein Toprim_2 PF13155.1 EAK89676.1 - 0.01 16.1 0.2 0.37 11.1 0.1 2.2 1 1 1 2 2 2 0 Toprim-like SPARC_Ca_bdg PF10591.4 EAK89676.1 - 0.015 15.3 0.0 5.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Nexin_C PF08628.7 EAK89676.1 - 0.016 15.3 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Sorting nexin C terminal DUF1257 PF06868.6 EAK89676.1 - 0.046 13.6 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) DUF2764 PF10962.3 EAK89676.1 - 0.047 12.9 0.3 0.062 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) PhageMin_Tail PF10145.4 EAK89676.1 - 0.081 12.5 0.4 0.2 11.2 0.3 1.5 2 0 0 2 2 2 0 Phage-related minor tail protein DUF3008 PF11450.3 EAK89676.1 - 0.098 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) DUF4601 PF15373.1 EAK89676.1 - 0.12 11.1 0.1 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) Glyco_trans_1_2 PF13524.1 EAK89676.1 - 0.16 12.2 0.1 9.4 6.5 0.0 2.3 1 1 1 2 2 2 0 Glycosyl transferases group 1 Endonuc-dimeris PF09124.5 EAK89676.1 - 0.16 11.5 0.7 1 9.0 0.0 2.6 3 0 0 3 3 3 0 T4 recombination endonuclease VII, dimerisation DNA_primase_lrg PF04104.9 EAK89678.1 - 2.4e-84 282.6 2.0 2.9e-84 282.3 0.1 1.9 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit TPT PF03151.11 EAK89679.1 - 8.2e-12 45.0 26.4 3.3e-09 36.5 5.5 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EAK89679.1 - 2.9e-05 24.1 32.6 0.00055 19.9 8.9 3.5 2 2 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EAK89679.1 - 0.0028 17.8 8.1 0.0028 17.8 5.6 3.1 2 2 1 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 EAK89679.1 - 0.22 10.3 24.1 0.56 9.0 16.7 1.7 1 1 0 1 1 1 0 UAA transporter family UPF0546 PF10639.4 EAK89679.1 - 0.31 10.8 6.3 2.6 7.9 0.8 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 WD40 PF00400.27 EAK89680.1 - 1.9e-58 192.3 18.6 1.6e-09 37.2 0.1 11.3 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 EAK89680.1 - 1.7 8.5 5.8 6.9 6.6 2.9 2.7 2 1 0 2 2 2 0 Dip2/Utp12 Family zf-C2H2_2 PF12756.2 EAK89681.1 - 6.2e-27 93.6 6.5 2.9e-24 85.1 1.3 2.9 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EAK89681.1 - 5.1e-08 32.8 1.9 0.0028 17.7 0.1 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EAK89681.1 - 0.00057 20.0 3.3 0.13 12.6 0.0 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EAK89681.1 - 0.00061 19.9 7.8 0.094 13.1 0.2 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 EAK89681.1 - 0.14 12.4 3.1 10 6.4 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EAK89681.1 - 0.21 11.5 0.1 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Fucokinase PF07959.7 EAK89682.1 - 0.067 11.7 0.0 0.1 11.1 0.0 1.3 1 0 0 1 1 1 0 L-fucokinase ATP-synt_ab PF00006.20 EAK89683.1 - 1.3e-59 201.2 0.0 1.8e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EAK89683.1 - 4.5e-17 62.5 0.0 8.9e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EAK89683.1 - 1.1e-11 44.7 1.3 2e-11 43.9 0.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EAK89683.1 - 3.3e-05 23.6 0.7 8.1e-05 22.4 0.5 1.6 1 0 0 1 1 1 1 HAS barrel domain Fe-ADH PF00465.14 EAK89684.1 - 3.1e-57 193.8 0.0 7.8e-56 189.2 0.0 2.0 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EAK89684.1 - 6.1e-10 38.8 1.1 5.6e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EAK89685.1 - 5e-111 370.8 0.0 7.1e-111 370.3 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EAK89685.1 - 2.1e-20 73.0 0.6 1.8e-10 40.5 0.0 2.5 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Aldedh PF00171.17 EAK89685.1 - 1.1e-16 60.2 0.0 4.7e-16 58.1 0.0 1.8 2 0 0 2 2 2 1 Aldehyde dehydrogenase family ThiF PF00899.16 EAK89686.1 - 2.2e-25 89.0 0.0 6.2e-25 87.5 0.0 1.6 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EAK89686.1 - 4e-15 55.1 0.1 1.4e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EAK89686.1 - 1.1e-11 43.8 0.9 2.2e-11 42.9 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EAK89686.1 - 0.0071 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 EAK89686.1 - 0.0081 15.7 0.8 0.06 12.9 0.0 2.3 2 0 0 2 2 2 1 MoeZ/MoeB domain eRF1_1 PF03463.10 EAK89687.1 - 5e-32 110.2 1.4 7.3e-32 109.7 0.6 1.6 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.10 EAK89687.1 - 7.4e-21 74.5 0.3 1.8e-19 70.0 0.0 3.1 2 1 1 3 3 3 1 eRF1 domain 3 eRF1_2 PF03464.10 EAK89687.1 - 3.6e-19 69.4 0.2 7.5e-19 68.3 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 2 WD40 PF00400.27 EAK89688.1 - 6.1e-09 35.4 3.9 0.064 13.1 0.1 5.2 5 1 0 5 5 5 3 WD domain, G-beta repeat NAD_kinase PF01513.16 EAK89689.1 - 4.2e-53 179.9 0.0 5.7e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase OGG_N PF07934.7 EAK89690.1 - 3.5e-32 110.7 0.2 1.3e-31 108.9 0.0 2.0 2 1 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EAK89690.1 - 8.3e-07 29.2 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein BTB_2 PF02214.17 EAK89691.1 - 5.6e-13 48.9 0.2 5.6e-13 48.9 0.1 2.0 2 1 0 2 2 2 1 BTB/POZ domain DUF3633 PF12315.3 EAK89691.1 - 0.0002 20.7 0.4 0.00031 20.1 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3633) BAF1_ABF1 PF04684.8 EAK89691.1 - 0.17 10.7 12.5 0.24 10.1 8.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Cytadhesin_P30 PF07271.6 EAK89691.1 - 0.23 10.7 3.6 0.29 10.3 2.5 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Gag_spuma PF03276.9 EAK89691.1 - 0.44 8.8 8.5 0.59 8.3 5.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Fimbrial_K88 PF02432.10 EAK89691.1 - 1 8.7 7.9 0.53 9.6 4.0 1.5 2 0 0 2 2 2 0 Fimbrial, major and minor subunit Mitochondr_Som1 PF11093.3 EAK89691.1 - 6.3 6.6 8.2 15 5.4 5.7 1.7 1 0 0 1 1 1 0 Mitochondrial export protein Som1 RCC1_2 PF13540.1 EAK89692.1 - 2.2e-27 94.0 0.2 2.4e-08 33.3 0.0 5.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EAK89692.1 - 1.3e-18 66.8 1.1 0.00014 21.9 0.0 7.3 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat Phosphodiest PF01663.17 EAK89693.1 - 3.7e-07 29.8 0.6 0.014 14.7 0.3 3.1 2 1 1 3 3 3 3 Type I phosphodiesterase / nucleotide pyrophosphatase CSD PF00313.17 EAK89694.1 - 1.2e-24 85.8 0.2 1.7e-24 85.3 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 EAK89694.1 - 8.9e-06 25.1 1.2 8.9e-06 25.1 0.8 2.2 2 1 0 2 2 2 1 Ribonuclease B OB domain FXR1P_C PF12235.3 EAK89694.1 - 0.00033 20.7 8.2 0.00047 20.2 5.7 1.2 1 0 0 1 1 1 1 Fragile X-related 1 protein C terminal DUF1633 PF07794.6 EAK89694.1 - 0.5 8.2 3.2 0.55 8.1 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) PfkB PF00294.19 EAK89695.1 - 4e-29 101.7 0.0 7.6e-29 100.7 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Ring_hydroxyl_A PF00848.14 EAK89695.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) RHD3 PF05879.7 EAK89696.1 - 8.7e-86 288.4 9.7 1.3e-83 281.2 6.7 2.0 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EAK89696.1 - 3.7e-06 26.2 0.2 9.9e-06 24.7 0.1 1.8 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EAK89696.1 - 0.0007 19.5 0.0 0.002 18.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAK89696.1 - 0.0019 18.0 0.1 0.0071 16.1 0.1 2.0 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EAK89696.1 - 0.0037 17.7 0.0 0.014 15.8 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EAK89696.1 - 0.0078 16.1 0.6 0.024 14.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain Ca_hom_mod PF14798.1 EAK89696.1 - 0.0083 15.1 0.5 0.029 13.3 0.0 2.0 2 0 0 2 2 2 1 Calcium homeostasis modulator zf-RING_2 PF13639.1 EAK89697.1 - 8e-12 44.8 6.1 1.4e-11 44.0 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EAK89697.1 - 1.4e-07 31.0 3.3 2.7e-07 30.1 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAK89697.1 - 7e-07 28.8 5.7 1.4e-06 27.8 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EAK89697.1 - 7.3e-07 29.2 8.0 3.2e-06 27.1 5.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EAK89697.1 - 8.1e-07 28.9 7.2 1.6e-06 28.0 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK89697.1 - 3e-05 23.6 4.4 6.5e-05 22.5 3.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EAK89697.1 - 0.0014 18.3 1.3 0.0032 17.2 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EAK89697.1 - 0.0057 16.3 0.9 0.0057 16.3 0.7 3.0 3 0 0 3 3 3 1 RING-type zinc-finger DUF1201 PF06716.6 EAK89697.1 - 0.0071 16.1 1.5 0.0071 16.1 1.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1201) FANCL_C PF11793.3 EAK89697.1 - 0.068 13.1 3.3 0.72 9.8 2.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.1 EAK89697.1 - 0.11 12.2 2.1 0.24 11.2 1.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EAK89697.1 - 0.21 11.4 5.8 0.5 10.2 4.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EAK89697.1 - 0.81 9.7 5.2 2 8.5 3.6 1.7 1 0 0 1 1 1 0 RING-variant domain zf-MIZ PF02891.15 EAK89697.1 - 7.8 6.1 7.6 6 6.4 4.0 1.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger FAD_binding_3 PF01494.14 EAK89698.1 - 2.5e-56 191.2 0.0 3e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EAK89698.1 - 3.9e-05 22.6 0.0 0.00015 20.7 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase MKT1_N PF12247.3 EAK89698.1 - 0.0063 16.8 0.0 0.021 15.1 0.0 1.9 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication NAD_binding_9 PF13454.1 EAK89699.1 - 0.00025 20.8 0.0 0.00083 19.1 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EAK89699.1 - 0.0021 18.0 0.0 0.005 16.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAK89699.1 - 0.0023 17.8 0.0 0.13 12.1 0.0 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAK89699.1 - 0.087 12.8 0.0 4.2 7.3 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAK89699.1 - 0.13 12.6 0.0 1 9.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UPRTase PF14681.1 EAK89700.1 - 8.4e-65 217.8 0.0 1.2e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 EAK89700.1 - 3.5e-47 160.4 0.1 5.3e-47 159.8 0.1 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EAK89700.1 - 3.1e-06 27.4 0.1 8.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAK89700.1 - 4.3e-05 24.3 0.2 0.00014 22.6 0.1 2.0 2 1 0 2 2 2 1 AAA domain CoaE PF01121.15 EAK89700.1 - 5.7e-05 22.5 0.1 0.3 10.4 0.0 2.4 2 0 0 2 2 2 2 Dephospho-CoA kinase Zeta_toxin PF06414.7 EAK89700.1 - 0.0036 16.4 0.0 0.0094 15.0 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 EAK89700.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EAK89700.1 - 0.1 12.2 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EAK89700.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_L1 PF00687.16 EAK89701.1 - 2.1e-49 167.8 2.7 2.5e-49 167.5 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family COPIIcoated_ERV PF07970.7 EAK89702.1 - 5.4e-52 176.6 3.4 9e-52 175.8 2.4 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EAK89702.1 - 5e-23 80.9 0.4 2e-22 78.9 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DNA_pol3_delta2 PF13177.1 EAK89703.1 - 1.3e-16 60.6 0.0 2.7e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EAK89703.1 - 1.1e-13 50.9 0.3 4.1e-13 49.1 0.1 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.24 EAK89703.1 - 3.1e-13 50.0 0.0 6.3e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EAK89703.1 - 3.9e-11 42.3 0.1 7.9e-08 31.4 0.0 2.3 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EAK89703.1 - 2.2e-08 34.2 0.0 4.7e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAK89703.1 - 9.2e-07 29.0 0.1 3.2e-05 24.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EAK89703.1 - 4e-06 26.5 0.0 6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EAK89703.1 - 8.1e-06 25.7 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EAK89703.1 - 1.8e-05 24.4 0.0 5.3e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EAK89703.1 - 0.00022 20.9 0.0 0.0006 19.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAK89703.1 - 0.00093 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EAK89703.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 EAK89703.1 - 0.0051 15.5 0.0 0.032 12.9 0.0 2.2 2 1 1 3 3 3 1 TIP49 C-terminus AAA_17 PF13207.1 EAK89703.1 - 0.008 16.9 0.0 0.025 15.3 0.0 1.9 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EAK89703.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EAK89703.1 - 0.012 14.8 0.0 5.3 6.2 0.0 2.3 1 1 1 2 2 2 0 PhoH-like protein DUF815 PF05673.8 EAK89703.1 - 0.016 14.1 0.0 0.043 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EAK89703.1 - 0.025 14.0 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EAK89703.1 - 0.027 14.7 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EAK89703.1 - 0.043 14.0 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 RNA helicase DEAD PF00270.24 EAK89703.1 - 0.047 13.1 0.1 1.5 8.2 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase SNF2_N PF00176.18 EAK89703.1 - 0.066 12.0 0.1 0.37 9.5 0.1 1.9 1 1 0 2 2 2 0 SNF2 family N-terminal domain Sigma54_activ_2 PF14532.1 EAK89703.1 - 0.067 13.2 0.2 1.1 9.3 0.2 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 EAK89703.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EAK89703.1 - 0.081 12.0 0.0 0.35 10.0 0.0 2.0 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EAK89703.1 - 0.093 12.1 0.0 0.15 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EAK89704.1 - 1.5e-61 207.1 0.1 2.2e-61 206.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EAK89704.1 - 4.7e-37 126.1 0.0 1.3e-36 124.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EAK89704.1 - 4.4e-21 74.5 0.0 1e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EAK89704.1 - 1.1e-14 53.9 0.0 2.5e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EAK89704.1 - 1.4e-11 44.3 0.2 3.5e-11 43.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAK89704.1 - 0.00019 21.3 0.0 0.00044 20.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pro-NT_NN PF07421.6 EAK89704.1 - 0.13 11.7 0.0 0.41 10.1 0.0 1.8 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor WD40 PF00400.27 EAK89705.1 - 1.3e-07 31.2 20.7 0.57 10.1 0.7 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat AA_kinase PF00696.23 EAK89705.1 - 0.05 13.1 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Amino acid kinase family Fcf2 PF08698.6 EAK89706.1 - 1.3e-24 86.0 2.9 2.4e-24 85.2 2.0 1.4 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Arm PF00514.18 EAK89707.1 - 2.9e-79 258.4 11.4 1.4e-12 46.8 0.0 10.2 10 0 0 10 10 10 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EAK89707.1 - 2.8e-24 85.1 0.0 2.4e-05 24.5 0.0 6.1 2 2 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 EAK89707.1 - 1.1e-17 63.9 0.0 4.8e-05 23.7 0.0 5.8 5 1 1 6 6 6 4 HEAT-like repeat HEAT PF02985.17 EAK89707.1 - 1e-15 56.2 0.5 0.0036 17.2 0.0 6.6 8 0 0 8 8 8 4 HEAT repeat IBB PF01749.15 EAK89707.1 - 1.8e-11 44.0 3.1 3.3e-11 43.1 2.1 1.4 1 0 0 1 1 1 1 Importin beta binding domain Adaptin_N PF01602.15 EAK89707.1 - 3.1e-05 22.5 0.0 0.1 10.8 0.0 3.2 2 2 0 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 EAK89707.1 - 0.00088 18.4 0.0 0.93 8.5 0.0 2.5 2 0 0 2 2 2 2 Armadillo-like Proteasom_PSMB PF10508.4 EAK89707.1 - 0.0018 16.6 0.2 0.93 7.6 0.0 3.1 2 1 2 4 4 4 2 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 EAK89707.1 - 0.013 15.4 0.0 5.1 7.0 0.0 3.7 2 1 3 5 5 5 0 V-ATPase subunit H ParcG PF10274.4 EAK89707.1 - 0.019 14.8 0.1 13 5.6 0.0 3.0 2 1 1 3 3 3 0 Parkin co-regulated protein SBDS PF01172.13 EAK89708.1 - 1.2e-33 114.7 1.0 5.4e-33 112.6 0.1 2.3 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 EAK89708.1 - 6.4e-28 96.9 2.3 1.5e-27 95.7 0.4 2.1 2 0 0 2 2 2 1 SBDS protein C-terminal domain zf-met PF12874.2 EAK89708.1 - 0.015 15.4 1.3 0.058 13.6 0.9 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EAK89708.1 - 0.066 13.3 2.3 0.18 11.9 1.6 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding B3_4 PF03483.12 EAK89709.1 - 2.3e-18 66.2 0.1 5.1e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EAK89709.1 - 4.5e-15 55.2 0.2 1.1e-11 44.3 0.1 2.8 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF2740 PF10872.3 EAK89709.1 - 0.12 12.0 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2740) RRM_1 PF00076.17 EAK89710.1 - 2.1e-26 91.3 0.2 1.8e-17 62.7 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK89710.1 - 3.4e-15 55.6 0.1 5.1e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK89710.1 - 4.1e-15 55.5 0.0 3.1e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAK89710.1 - 0.016 15.0 0.1 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.1 EAK89710.1 - 0.034 13.9 0.1 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif HEAT_EZ PF13513.1 EAK89711.1 - 1.5e-17 63.5 2.0 2.9e-07 30.7 0.0 7.2 8 0 0 8 8 8 3 HEAT-like repeat HEAT PF02985.17 EAK89711.1 - 5.8e-15 53.9 7.4 0.00068 19.5 0.0 8.8 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 EAK89711.1 - 1.9e-12 47.2 0.0 0.00014 22.1 0.0 5.1 3 2 2 5 5 5 4 HEAT repeats Arm PF00514.18 EAK89711.1 - 3.1e-05 23.6 4.2 0.0097 15.7 0.4 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 EAK89711.1 - 0.041 13.7 0.4 0.25 11.2 0.0 2.7 3 0 0 3 3 3 0 Importin-beta N-terminal domain tRNA-synt_1g PF09334.6 EAK89712.1 - 4e-109 364.8 1.6 1.3e-62 211.6 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EAK89712.1 - 2.3e-32 111.8 3.0 3.3e-17 61.7 0.1 3.8 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EAK89712.1 - 6.1e-13 48.5 0.0 1e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EAK89712.1 - 0.0013 17.4 0.0 1.1 7.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) Anticodon_1 PF08264.8 EAK89712.1 - 0.027 14.2 0.0 0.083 12.6 0.0 1.9 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA DUF2072 PF09845.4 EAK89712.1 - 0.16 11.9 1.8 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) Ribosomal_L34e PF01199.13 EAK89713.1 - 6.2e-35 119.2 6.5 6.2e-35 119.2 4.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L34e DUF2387 PF09526.5 EAK89713.1 - 0.013 15.3 0.4 0.027 14.4 0.3 1.6 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) PITH PF06201.8 EAK89714.1 - 1.6e-26 92.9 2.9 1.8e-26 92.7 2.0 1.0 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.8 EAK89714.1 - 0.01 15.6 0.1 0.017 14.9 0.1 1.4 1 1 0 1 1 1 0 Sad1 / UNC-like C-terminal DUF974 PF06159.8 EAK89716.1 - 2e-15 56.9 0.9 2.2e-15 56.8 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF974) Trs65 PF12735.2 EAK89716.1 - 0.00035 20.0 0.7 0.0012 18.2 0.1 2.0 1 1 0 2 2 2 1 TRAPP trafficking subunit Trs65 DUF4352 PF11611.3 EAK89716.1 - 0.0012 19.0 1.5 0.61 10.2 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4352) SVA PF05326.6 EAK89716.1 - 0.066 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) RTC PF01137.16 EAK89717.1 - 1.2e-41 142.0 0.0 1.5e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EAK89717.1 - 6.6e-14 51.7 0.0 2.8e-13 49.7 0.0 2.0 3 0 0 3 3 3 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain TFIIE_beta PF02186.10 EAK89717.1 - 0.067 13.1 0.1 0.69 9.9 0.0 2.5 2 0 0 2 2 2 0 TFIIE beta subunit core domain Carboxyl_trans PF01039.17 EAK89718.1 - 2e-141 471.7 0.0 2.7e-141 471.2 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EAK89718.1 - 1.1e-47 162.0 1.0 2.4e-47 160.9 0.7 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ACC_central PF08326.7 EAK89718.1 - 7.3e-37 126.8 8.7 3.7e-18 65.0 3.5 3.9 3 2 0 3 3 3 3 Acetyl-CoA carboxylase, central region CPSase_L_chain PF00289.17 EAK89718.1 - 2.1e-25 88.9 0.0 7.9e-25 87.1 0.0 2.1 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EAK89718.1 - 4.1e-20 71.7 0.0 1.3e-19 70.1 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EAK89718.1 - 6e-13 48.9 0.0 1.5e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EAK89718.1 - 2.9e-09 36.4 0.0 6.5e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EAK89718.1 - 1e-07 31.5 0.3 2.6e-07 30.2 0.2 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EAK89718.1 - 9e-05 21.8 0.2 0.00021 20.6 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain DnaJ PF00226.26 EAK89719.1 - 9.1e-26 89.3 1.5 1.8e-25 88.4 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EAK89719.1 - 1.8e-21 75.8 4.5 1e-20 73.3 0.2 3.4 4 0 0 4 4 4 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EAK89719.1 - 8.9e-14 51.2 15.2 1.5e-13 50.5 10.5 1.4 1 0 0 1 1 1 1 DnaJ central domain zf-SNAP50_C PF12251.3 EAK89719.1 - 0.24 10.7 1.5 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal HypA PF01155.14 EAK89719.1 - 1.2 8.8 8.9 2.1 8.0 0.4 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family TRAUB PF08164.7 EAK89720.1 - 6.1e-24 83.9 0.0 9.7e-24 83.2 0.0 1.3 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal EII-GUT PF03608.8 EAK89720.1 - 0.065 13.0 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor KKLCAg1 PF15204.1 EAK89720.1 - 0.087 12.8 0.7 0.23 11.5 0.1 1.8 1 1 1 2 2 2 0 Kita-kyushu lung cancer antigen 1 DEAD PF00270.24 EAK89721.1 - 1e-34 119.4 0.2 1.9e-34 118.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK89721.1 - 3.2e-25 87.7 0.9 7.3e-25 86.6 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EAK89721.1 - 0.0024 16.3 1.0 0.0081 14.6 0.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1253) ResIII PF04851.10 EAK89721.1 - 0.0053 16.6 0.0 0.018 14.8 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EAK89721.1 - 0.0061 15.6 0.1 0.013 14.6 0.1 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit tRNA-synt_1b PF00579.20 EAK89721.1 - 0.023 13.8 0.0 0.84 8.6 0.0 2.3 1 1 0 2 2 2 0 tRNA synthetases class I (W and Y) ChaC PF04752.7 EAK89721.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 ChaC-like protein MutS_V PF00488.16 EAK89722.1 - 3.6e-84 281.8 0.1 6.2e-84 281.0 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EAK89722.1 - 9.1e-29 100.7 1.1 2e-28 99.5 0.1 2.2 2 1 0 2 2 2 1 MutS domain III DUF2884 PF11101.3 EAK89722.1 - 0.011 15.1 0.8 0.036 13.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) NAP PF00956.13 EAK89723.1 - 1e-28 100.0 11.4 1.3e-28 99.7 7.9 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Clat_adaptor_s PF01217.15 EAK89724.1 - 2.6e-51 173.0 3.0 3.4e-51 172.7 2.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCI PF01399.22 EAK89725.1 - 3.7e-17 62.5 2.9 1.6e-16 60.5 0.0 3.1 3 1 0 3 3 3 1 PCI domain Rpn3_C PF08375.6 EAK89725.1 - 6.5e-07 29.6 0.1 6.5e-07 29.6 0.1 3.1 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.12 EAK89725.1 - 0.014 15.2 0.3 0.12 12.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S14 PF00253.16 EAK89726.1 - 8.7e-18 63.4 6.4 1e-17 63.2 4.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e EF-hand_1 PF00036.27 EAK89727.1 - 1.6e-19 67.6 6.7 4e-06 25.7 1.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EAK89727.1 - 1e-17 62.3 2.7 9.8e-07 28.1 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EAK89727.1 - 5.4e-17 61.1 4.7 3.8e-08 32.8 0.3 4.4 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EAK89727.1 - 8.6e-15 53.3 3.3 7.8e-05 21.8 0.3 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EAK89727.1 - 2.5e-14 53.1 8.6 2.9e-06 27.2 1.2 3.6 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 EAK89727.1 - 5.5e-07 29.4 0.5 0.2 11.5 0.0 3.7 3 1 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 EAK89727.1 - 0.014 15.1 5.0 0.52 10.0 0.4 3.6 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EAK89727.1 - 0.12 12.0 1.9 4.7 6.9 0.0 3.7 4 1 1 5 5 5 0 EF hand RRM_1 PF00076.17 EAK89728.1 - 2.1e-09 36.8 0.3 5e-09 35.6 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK89728.1 - 2e-07 30.8 0.2 3.9e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK89728.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mso1_C PF14477.1 EAK89729.1 - 7.5 6.9 6.6 7.2 7.0 0.1 3.6 3 0 0 3 3 3 0 Membrane-polarising domain of Mso1 Methyltransf_23 PF13489.1 EAK89731.1 - 1.4e-12 47.5 0.0 1.9e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAK89731.1 - 3e-07 31.0 0.0 5.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAK89731.1 - 3.9e-07 30.4 0.0 1.6e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAK89731.1 - 9.2e-05 22.0 0.1 0.00044 19.8 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAK89731.1 - 0.00016 21.9 0.0 0.00065 20.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EAK89731.1 - 0.0019 17.3 0.0 0.0031 16.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EAK89731.1 - 0.01 15.8 0.0 0.019 15.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EAK89731.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EAK89731.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Kri1_C PF12936.2 EAK89732.1 - 3.1e-28 97.5 3.0 3.1e-28 97.5 2.1 6.1 6 1 0 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.7 EAK89732.1 - 1.8e-20 73.0 17.6 1.8e-20 73.0 12.2 5.0 3 2 0 3 3 3 1 KRI1-like family ZZ PF00569.12 EAK89732.1 - 0.064 12.8 9.7 0.16 11.5 6.4 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type Ribosomal_S8 PF00410.14 EAK89733.1 - 3e-24 85.3 0.0 4.1e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 ACPS PF01648.15 EAK89734.1 - 1.4e-14 53.9 0.0 8e-13 48.2 0.0 2.2 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily DnaJ PF00226.26 EAK89735.1 - 4.5e-18 64.7 4.1 1.3e-17 63.3 2.9 1.9 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 EAK89736.1 - 5.9e-11 41.8 1.3 1.9e-05 24.1 0.0 3.9 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK89736.1 - 1.1e-08 34.7 1.3 0.00042 20.1 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK89736.1 - 2.2e-08 33.9 0.0 0.0032 17.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2652 PF10851.3 EAK89736.1 - 0.055 13.4 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2652) RRM_5 PF13893.1 EAK89737.1 - 1.8e-09 37.2 0.0 3.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EAK89737.1 - 4.3e-08 32.6 15.0 2.2e-05 23.9 1.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 EAK89737.1 - 6.3e-05 22.5 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK89737.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PseudoU_synth_1 PF01416.15 EAK89738.1 - 2.8e-30 104.8 0.0 6.3e-22 77.9 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.4 EAK89738.1 - 0.086 12.3 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) TFIID-31kDa PF02291.10 EAK89738.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit HhH-GPD PF00730.20 EAK89739.1 - 1.5e-16 60.6 0.2 5.5e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein UQ_con PF00179.21 EAK89740.1 - 2.4e-18 65.9 0.0 4.9e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF106 PF01956.11 EAK89741.1 - 1.2e-23 83.5 0.0 4e-23 81.7 0.0 1.7 1 1 0 1 1 1 1 Integral membrane protein DUF106 DUF4083 PF13314.1 EAK89741.1 - 0.017 14.9 0.1 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Adipogenin PF15202.1 EAK89741.1 - 1.8 8.4 5.4 3 7.7 0.0 2.9 3 0 0 3 3 3 0 Adipogenin Zip PF02535.17 EAK89742.1 - 8.7e-05 21.6 0.5 0.00014 20.9 0.4 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter COPI_assoc PF08507.5 EAK89743.1 - 2.3e-26 92.0 19.2 2.7e-26 91.9 13.3 1.0 1 0 0 1 1 1 1 COPI associated protein Caveolin PF01146.12 EAK89743.1 - 3.1 7.3 5.6 1.9 8.0 2.7 1.5 1 1 0 1 1 1 0 Caveolin Fip1 PF05182.8 EAK89745.1 - 1.1e-09 37.3 0.5 2.3e-09 36.3 0.3 1.4 1 0 0 1 1 1 1 Fip1 motif RRM_1 PF00076.17 EAK89746.1 - 6.4e-17 60.9 0.0 1.1e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK89746.1 - 2.3e-15 56.3 0.0 3.7e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK89746.1 - 2.1e-09 37.0 0.0 3.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2615 PF11027.3 EAK89747.1 - 0.069 13.0 0.2 19 5.2 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2615) Ycf1 PF05758.7 EAK89747.1 - 4.5 4.8 13.4 7 4.2 9.3 1.3 1 0 0 1 1 1 0 Ycf1 DUF1869 PF08956.5 EAK89748.1 - 0.054 13.1 1.6 0.086 12.4 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) DUF2418 PF10332.4 EAK89748.1 - 0.083 13.1 0.1 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) PP2C PF00481.16 EAK89749.1 - 2.4e-14 53.3 0.0 1.3e-10 41.1 0.0 2.6 1 1 0 1 1 1 1 Protein phosphatase 2C Rsd_AlgQ PF04353.8 EAK89750.1 - 0.0012 18.5 1.3 0.013 15.2 0.0 2.2 2 1 0 2 2 2 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ RasGEF PF00617.14 EAK89750.1 - 0.15 11.7 8.4 2.6 7.7 0.2 3.0 1 1 1 3 3 3 0 RasGEF domain Trypan_glycop PF00913.14 EAK89752.1 - 7.9 5.2 13.3 0.4 9.5 5.5 1.6 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein (A-type) Zip PF02535.17 EAK89753.1 - 1.9e-36 125.7 15.4 1.9e-36 125.7 10.7 2.8 1 1 1 2 2 2 1 ZIP Zinc transporter Menin PF05053.8 EAK89753.1 - 0.23 9.5 7.3 0.33 9.0 5.1 1.1 1 0 0 1 1 1 0 Menin Synaptobrevin PF00957.16 EAK89754.1 - 3.1e-15 55.5 0.6 4.9e-15 54.8 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EAK89754.1 - 7.6e-08 31.8 0.0 1.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain PDEase_I PF00233.14 EAK89755.1 - 4.4e-58 196.8 2.4 4.4e-58 196.8 1.6 2.3 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 EAK89755.1 - 0.019 14.9 0.0 0.09 12.7 0.0 2.1 1 0 0 1 1 1 0 HD domain Pkinase PF00069.20 EAK89756.1 - 2.3e-73 246.5 0.0 2.3e-73 246.5 0.0 3.1 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK89756.1 - 7.5e-39 133.3 0.0 1.3e-38 132.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAK89756.1 - 0.012 14.7 0.1 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAK89756.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PCYCGC PF13798.1 EAK89757.1 - 1.6 8.4 6.9 0.53 9.9 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif Pkinase PF00069.20 EAK89758.1 - 3.9e-08 32.7 1.7 8.1e-08 31.7 1.2 1.5 1 0 0 1 1 1 1 Protein kinase domain RWD PF05773.17 EAK89758.1 - 0.00027 20.8 3.3 0.00033 20.5 0.5 2.6 2 0 0 2 2 2 1 RWD domain AAA PF00004.24 EAK89759.1 - 3.6e-31 108.0 0.0 6.9e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EAK89759.1 - 6.1e-06 27.0 0.6 3.4e-05 24.6 0.1 2.4 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EAK89759.1 - 0.00038 19.5 0.3 0.0019 17.2 0.2 2.3 1 1 0 1 1 1 1 KAP family P-loop domain AAA_18 PF13238.1 EAK89759.1 - 0.0011 19.2 0.8 0.0032 17.7 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EAK89759.1 - 0.0016 18.1 0.4 0.018 14.7 0.1 2.8 2 2 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAK89759.1 - 0.0024 18.0 0.0 0.007 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EAK89759.1 - 0.0033 17.1 0.0 0.0097 15.5 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAK89759.1 - 0.0034 17.3 0.0 0.0085 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 EAK89759.1 - 0.0063 15.2 0.0 0.014 14.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 EAK89759.1 - 0.0064 16.6 0.1 0.074 13.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.8 EAK89759.1 - 0.0064 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KaiC PF06745.8 EAK89759.1 - 0.012 14.7 0.6 3.4 6.7 0.0 2.7 1 1 1 2 2 2 0 KaiC DnaB_C PF03796.10 EAK89759.1 - 0.015 14.2 0.0 0.028 13.2 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 EAK89759.1 - 0.015 14.4 0.2 0.15 11.1 0.0 2.5 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EAK89759.1 - 0.015 14.3 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EAK89759.1 - 0.021 14.4 0.5 0.26 10.8 0.3 2.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAK89759.1 - 0.021 14.8 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EAK89759.1 - 0.029 13.4 0.0 0.055 12.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus UPF0079 PF02367.12 EAK89759.1 - 0.063 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 EAK89759.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 EAK89759.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EAK89759.1 - 0.086 12.2 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 EAK89759.1 - 0.19 11.4 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Beta-Casp PF10996.3 EAK89760.1 - 2.1e-24 85.8 0.8 8.2e-23 80.7 0.0 3.5 3 0 0 3 3 3 1 Beta-Casp domain Pex14_N PF04695.8 EAK89760.1 - 0.0091 16.0 6.7 0.0091 16.0 4.7 2.4 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PepSY_2 PF13670.1 EAK89760.1 - 0.27 11.1 0.1 0.5 10.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Asp PF00026.18 EAK89762.1 - 1.7e-52 178.6 0.0 2.7e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAK89762.1 - 6.3e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EAK89762.1 - 0.00083 18.9 0.0 0.024 14.2 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal CDC45 PF02724.9 EAK89762.1 - 0.023 12.7 3.5 0.03 12.3 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 EAK89762.1 - 2.3 6.8 15.4 3.2 6.3 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Peptidase_C11 PF03415.9 EAK89763.1 - 1.7e-23 83.2 3.0 2.5e-23 82.7 0.1 2.9 2 1 0 2 2 2 1 Clostripain family EGF_3 PF12947.2 EAK89763.1 - 6e-13 48.5 29.5 3.7e-09 36.3 2.1 4.9 4 0 0 4 4 4 2 EGF domain cEGF PF12662.2 EAK89763.1 - 6.1e-10 38.5 27.7 0.0017 17.9 3.3 4.9 4 0 0 4 4 4 4 Complement Clr-like EGF-like EGF_CA PF07645.10 EAK89763.1 - 1.6e-09 37.5 19.9 1.1e-06 28.4 2.0 6.1 6 0 0 6 6 6 2 Calcium-binding EGF domain EGF PF00008.22 EAK89763.1 - 0.00016 21.5 32.0 0.0021 17.9 2.2 4.5 4 0 0 4 4 4 2 EGF-like domain FXa_inhibition PF14670.1 EAK89763.1 - 0.0019 18.2 31.7 0.055 13.6 5.1 4.8 5 0 0 5 5 5 2 Coagulation Factor Xa inhibitory site hEGF PF12661.2 EAK89763.1 - 0.12 12.5 14.8 0.28 11.3 0.8 4.2 3 0 0 3 3 3 0 Human growth factor-like EGF TIL PF01826.12 EAK89763.1 - 4.4 7.4 23.1 0.38 10.9 3.2 4.5 4 0 0 4 4 4 0 Trypsin Inhibitor like cysteine rich domain CEP76-C2 PF15627.1 EAK89764.1 - 1.3e-05 24.7 0.0 3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 CEP76 C2 domain C2 PF00168.25 EAK89764.1 - 4.6e-05 23.1 0.0 0.00027 20.6 0.0 2.4 1 1 0 1 1 1 1 C2 domain Cnd1 PF12717.2 EAK89766.1 - 1.8e-43 148.4 2.0 1.8e-43 148.4 1.4 5.7 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 EAK89766.1 - 0.01 15.7 2.1 9.2 6.3 0.2 4.8 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Rhomboid PF01694.17 EAK89768.1 - 1.2e-28 99.9 15.9 1.2e-28 99.9 11.0 1.9 3 0 0 3 3 3 1 Rhomboid family Sdh_cyt PF01127.17 EAK89768.1 - 0.59 9.9 8.8 6.1 6.7 1.2 2.9 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ribonuc_red_sm PF00268.16 EAK89769.1 - 1.3e-106 355.7 3.6 1.8e-106 355.2 2.5 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain TryThrA_C PF12319.3 EAK89769.1 - 0.87 8.7 14.6 0.071 12.2 5.8 2.0 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal BRCT PF00533.21 EAK89770.1 - 0.00031 20.8 2.8 0.015 15.4 0.1 3.3 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain FHA PF00498.21 EAK89770.1 - 0.0014 18.7 0.2 0.005 16.9 0.0 2.0 2 0 0 2 2 2 1 FHA domain His_Phos_1 PF00300.17 EAK89770.1 - 0.069 13.2 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) DASH_Dad3 PF08656.5 EAK89771.1 - 0.99 9.1 11.7 3.1 7.5 1.2 3.4 3 0 0 3 3 3 0 DASH complex subunit Dad3 Tnp_P_element PF12017.3 EAK89771.1 - 2.1 7.4 8.6 3.6 6.7 1.9 2.3 1 1 1 2 2 2 0 Transposase protein PH_6 PF15406.1 EAK89772.1 - 0.00027 20.9 0.0 0.016 15.2 0.0 3.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EAK89772.1 - 0.00031 20.7 0.0 0.0014 18.6 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_A22B PF04258.8 EAK89773.1 - 7.9e-69 232.3 14.8 1.2e-68 231.7 10.3 1.3 1 0 0 1 1 1 1 Signal peptide peptidase Pex24p PF06398.6 EAK89773.1 - 0.11 11.2 0.0 0.11 11.2 0.0 2.5 3 1 0 3 3 3 0 Integral peroxisomal membrane peroxin DUF4131 PF13567.1 EAK89773.1 - 4.5 6.6 0.0 4.5 6.6 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) SIP1 PF04938.7 EAK89774.1 - 0.02 14.2 3.6 0.029 13.7 2.5 1.3 1 1 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Imm31 PF15595.1 EAK89774.1 - 0.027 14.2 3.5 0.11 12.2 0.1 2.9 1 1 1 3 3 3 0 Immunity protein 31 DUF410 PF04190.8 EAK89775.1 - 2.6e-18 66.5 5.8 3.2e-18 66.2 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) hDGE_amylase PF14701.1 EAK89776.1 - 3.3e-113 378.7 9.6 3.3e-113 378.7 6.6 3.3 2 1 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EAK89776.1 - 1.2e-99 333.5 0.2 2.7e-99 332.4 0.2 1.6 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EAK89776.1 - 5.7e-48 163.3 0.2 5.7e-48 163.3 0.1 2.2 2 0 0 2 2 2 1 central domain of human glycogen debranching enzyme Shugoshin_C PF07557.6 EAK89777.1 - 0.0014 18.0 0.4 0.0026 17.1 0.3 1.5 1 0 0 1 1 1 1 Shugoshin C terminus Toxin_63 PF15541.1 EAK89777.1 - 0.08 12.9 0.6 0.15 12.0 0.4 1.4 1 0 0 1 1 1 0 Putative toxin 63 SPATIAL PF15256.1 EAK89777.1 - 2.8 7.9 6.5 4.1 7.4 4.1 1.5 1 1 0 1 1 1 0 SPATIAL Sec20 PF03908.8 EAK89778.1 - 1.3e-10 40.7 2.7 1.9e-10 40.3 1.9 1.2 1 0 0 1 1 1 1 Sec20 Uso1_p115_C PF04871.8 EAK89778.1 - 0.014 15.2 4.5 0.018 15.0 3.1 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Herpes_UL92 PF03048.9 EAK89778.1 - 0.027 14.0 0.9 0.037 13.5 0.6 1.2 1 0 0 1 1 1 0 UL92 family Laminin_II PF06009.7 EAK89778.1 - 0.087 12.5 4.1 0.11 12.1 2.8 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF4407 PF14362.1 EAK89778.1 - 0.15 11.0 0.2 0.19 10.6 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.5 EAK89778.1 - 0.97 9.5 4.6 1.3 9.1 3.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 EAK89778.1 - 2.8 6.2 5.4 3.6 5.8 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SPT6_acidic PF14632.1 EAK89778.1 - 3 8.0 5.9 3.8 7.7 4.1 1.1 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Peptidase_C78 PF07910.8 EAK89779.1 - 6.8e-45 152.8 0.5 1.3e-44 151.9 0.4 1.5 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.14 EAK89779.1 - 0.0016 17.5 0.0 0.0043 16.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase family C54 DUF3906 PF13046.1 EAK89779.1 - 0.072 12.7 0.0 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) RrnaAD PF00398.15 EAK89780.1 - 2.1e-51 174.4 0.0 3e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 EAK89780.1 - 3.1e-10 39.8 0.0 1.2e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAK89780.1 - 4.8e-09 36.7 0.0 3.5e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAK89780.1 - 5.6e-09 36.0 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAK89780.1 - 1.6e-06 28.4 0.1 6.5e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAK89780.1 - 2.3e-06 27.9 0.0 5.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAK89780.1 - 1.9e-05 24.0 0.1 4.6e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EAK89780.1 - 3.8e-05 23.4 0.0 6.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAK89780.1 - 0.00014 21.0 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EAK89780.1 - 0.00072 19.8 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAK89780.1 - 0.0037 16.4 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EAK89780.1 - 0.0046 16.0 0.0 0.011 14.7 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 EAK89780.1 - 0.0068 15.9 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LCM PF04072.9 EAK89780.1 - 0.017 14.7 0.0 0.038 13.5 0.0 1.5 2 0 0 2 2 2 0 Leucine carboxyl methyltransferase DREV PF05219.7 EAK89780.1 - 0.028 13.2 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase NodS PF05401.6 EAK89780.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Pescadillo_N PF06732.6 EAK89781.1 - 6.3e-96 320.9 2.7 6.3e-96 320.9 1.9 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EAK89781.1 - 4.1e-09 36.4 0.4 1.2e-08 34.9 0.1 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain CRAL_TRIO PF00650.15 EAK89782.1 - 3.4e-29 101.4 0.0 7e-29 100.3 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EAK89782.1 - 9.5e-11 41.8 0.0 2.6e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EAK89782.1 - 1.3e-05 25.2 0.5 0.00036 20.5 0.0 2.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain SET PF00856.23 EAK89783.1 - 3.2e-06 27.5 0.1 1.9e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 SET domain U1snRNP70_N PF12220.3 EAK89784.1 - 2.3e-19 69.4 3.8 4.6e-19 68.5 2.6 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EAK89784.1 - 8.8e-18 63.7 0.1 1.6e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK89784.1 - 2.8e-14 52.8 0.0 6e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK89784.1 - 5.7e-08 32.5 0.1 2.1e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3242 PF11586.3 EAK89784.1 - 0.074 12.5 0.8 1.2 8.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3242) OB_RNB PF08206.6 EAK89784.1 - 0.15 11.6 0.3 0.49 9.9 0.2 1.9 1 1 0 1 1 1 0 Ribonuclease B OB domain CDC27 PF09507.5 EAK89785.1 - 1.1 8.3 48.0 1.5 7.9 33.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 EAK89785.1 - 1.3 7.4 59.3 1.8 6.9 41.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PP2C PF00481.16 EAK89786.1 - 2.5e-14 53.3 0.2 1.2e-05 24.8 0.0 3.4 3 0 0 3 3 3 3 Protein phosphatase 2C PP2C_2 PF13672.1 EAK89786.1 - 0.0021 17.4 0.0 0.13 11.6 0.0 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C IF4E PF01652.13 EAK89787.1 - 7.5e-41 139.4 0.5 1e-40 139.0 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Rpr2 PF04032.11 EAK89788.1 - 1.5e-20 72.8 2.5 1.9e-20 72.4 1.7 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain NinG PF05766.7 EAK89788.1 - 0.92 9.2 6.2 1.4 8.6 1.1 2.2 2 1 0 2 2 2 0 Bacteriophage Lambda NinG protein GidB PF02527.10 EAK89789.1 - 0.022 13.9 0.4 0.068 12.3 0.3 1.8 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G NifU_N PF01592.11 EAK89790.1 - 3.1e-45 153.2 0.1 3.5e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DUF1077 PF06417.7 EAK89792.1 - 3.1e-30 104.1 0.4 4.3e-30 103.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Virul_fac_BrkB PF03631.10 EAK89792.1 - 0.032 13.6 0.1 0.04 13.2 0.1 1.1 1 0 0 1 1 1 0 Virulence factor BrkB GP40 PF11025.3 EAK89793.1 - 1.1e-97 324.3 1.7 1.1e-97 324.3 1.1 2.5 2 1 1 3 3 3 1 Glycoprotein GP40 of Cryptosporidium FLgD_tudor PF13861.1 EAK89793.1 - 0.65 10.0 7.2 1.3 9.0 5.0 1.7 1 1 0 1 1 1 0 FlgD Tudor-like domain SR-25 PF10500.4 EAK89793.1 - 1.4 8.3 26.5 0.019 14.4 10.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SoxE PF06525.6 EAK89793.1 - 8.8 5.5 7.5 1.6 7.9 1.8 2.1 2 0 0 2 2 2 0 Sulfocyanin (SoxE) Na_trans_assoc PF06512.8 EAK89793.1 - 9.6 6.0 9.6 2.3 8.1 3.0 2.0 2 0 0 2 2 2 0 Sodium ion transport-associated Asp-B-Hydro_N PF05279.6 EAK89794.1 - 5.7 6.7 33.7 11 5.8 23.3 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Sec2p PF06428.6 EAK89797.1 - 3.6 7.4 13.3 0.69 9.7 2.9 2.7 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p AP2 PF00847.15 EAK89798.1 - 1.1e-06 28.6 3.8 1.6e-05 24.9 1.2 2.4 2 0 0 2 2 2 2 AP2 domain ADAM_spacer1 PF05986.9 EAK89801.1 - 0.077 12.8 0.4 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 ADAM-TS Spacer 1 Methyltransf_PK PF05891.7 EAK89803.1 - 6.9e-43 146.4 0.0 8.5e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.7 EAK89803.1 - 2.1e-05 24.9 0.0 5.8e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAK89803.1 - 7.7e-05 22.9 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAK89803.1 - 0.0014 19.2 0.0 0.0045 17.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain NodS PF05401.6 EAK89803.1 - 0.0034 16.8 0.0 0.0045 16.3 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.7 EAK89803.1 - 0.052 14.0 0.0 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EAK89803.1 - 0.11 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Clp1 PF06807.9 EAK89805.1 - 2.1e-07 30.9 0.2 4.6e-07 29.7 0.2 1.6 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EAK89805.1 - 3.7e-05 23.4 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EAK89805.1 - 0.00045 20.1 0.1 0.0018 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EAK89805.1 - 0.0064 17.3 0.0 0.021 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EAK89805.1 - 0.021 15.0 0.0 0.05 13.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EAK89805.1 - 0.029 14.5 0.0 0.077 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EAK89805.1 - 0.047 13.8 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EAK89805.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 EAK89805.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EAK89805.1 - 0.087 12.5 1.9 0.087 12.5 0.0 1.9 3 0 0 3 3 3 0 Archaeal ATPase AAA_18 PF13238.1 EAK89805.1 - 0.1 12.8 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EAK89805.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EAK89805.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain zf-RING_2 PF13639.1 EAK89810.1 - 1.2e-14 53.8 8.4 2.6e-14 52.7 5.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAK89810.1 - 1.4e-09 37.9 4.7 3e-09 36.8 3.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EAK89810.1 - 3.3e-07 29.8 10.8 7.6e-07 28.6 7.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAK89810.1 - 2.9e-06 26.8 6.8 6.2e-06 25.7 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK89810.1 - 5.6e-06 26.2 11.2 5.6e-06 26.2 7.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK89810.1 - 2.4e-05 23.9 8.5 5e-05 22.9 5.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EAK89810.1 - 0.0038 17.0 2.7 0.0068 16.2 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EAK89810.1 - 0.024 14.6 8.4 0.15 12.0 6.5 1.8 2 0 0 2 2 2 0 RING-variant domain zf-RING_6 PF14835.1 EAK89810.1 - 0.039 13.7 2.3 0.097 12.4 1.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_1 PF14446.1 EAK89810.1 - 0.069 12.9 6.8 0.047 13.4 2.0 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-LITAF-like PF10601.4 EAK89810.1 - 0.13 12.0 0.5 0.13 12.0 0.4 2.5 2 1 0 2 2 1 0 LITAF-like zinc ribbon domain zf-RING_UBOX PF13445.1 EAK89810.1 - 0.19 11.4 7.8 0.55 9.9 5.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAK89810.1 - 1.8 8.5 9.9 38 4.2 6.8 2.6 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EAK89810.1 - 3.4 7.7 9.7 32 4.5 6.7 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain PAN_4 PF14295.1 EAK89811.1 - 0.01 15.5 0.0 0.01 15.5 0.0 3.8 4 1 0 4 4 4 0 PAN domain Me-amine-dh_L PF02975.9 EAK89811.1 - 0.012 15.6 0.9 0.012 15.6 0.6 3.4 2 2 1 4 4 4 0 Methylamine dehydrogenase, L chain PAN_2 PF08276.6 EAK89811.1 - 0.016 15.0 0.1 0.016 15.0 0.1 4.1 4 2 1 5 5 5 0 PAN-like domain DUF4190 PF13828.1 EAK89813.1 - 0.6 9.6 3.1 1 8.9 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) QueF PF14489.1 EAK89814.1 - 0.35 10.8 2.5 8 6.4 0.0 3.8 3 1 1 4 4 4 0 QueF-like protein CesA PF11439.3 EAK89814.1 - 0.97 9.3 5.0 0.31 10.9 0.6 2.2 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA START PF01852.14 EAK89815.1 - 1.3e-09 37.6 0.1 2.6e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 START domain Hus1 PF04005.7 EAK89817.1 - 1.3e-15 57.0 5.5 2.3e-15 56.3 3.8 1.4 1 0 0 1 1 1 1 Hus1-like protein DUF814 PF05670.8 EAK89817.1 - 0.046 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF814) RRM_3 PF08777.6 EAK89818.1 - 0.045 13.6 0.2 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif DUF1759 PF03564.10 EAK89818.1 - 0.045 13.5 1.5 0.066 13.0 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) ING PF12998.2 EAK89818.1 - 0.046 13.9 0.9 0.077 13.2 0.6 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding IL2 PF00715.12 EAK89818.1 - 0.17 11.5 2.4 0.28 10.9 1.5 1.6 1 1 0 1 1 1 0 Interleukin 2 E2F_TDP PF02319.15 EAK89819.1 - 1e-17 63.4 0.0 1.9e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain SET PF00856.23 EAK89820.1 - 3.9e-09 37.0 5.0 2.4e-07 31.1 0.0 3.3 3 1 0 3 3 3 2 SET domain Pik1 PF11522.3 EAK89820.1 - 0.0027 17.3 0.2 0.012 15.3 0.2 2.2 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 CRAL_TRIO PF00650.15 EAK89821.1 - 2.5e-29 101.7 0.2 5.9e-29 100.6 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EAK89821.1 - 2.7e-09 37.0 0.1 4e-08 33.2 0.0 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain PKD_channel PF08016.7 EAK89823.1 - 0.017 13.6 24.5 0.03 12.7 17.0 1.4 1 0 0 1 1 1 0 Polycystin cation channel Ninjurin PF04923.7 EAK89823.1 - 0.098 12.3 4.4 0.39 10.4 3.1 2.0 2 1 0 2 2 2 0 Ninjurin Surf_Ag_VNR PF07244.10 EAK89823.1 - 1 9.8 4.7 0.62 10.5 1.6 1.9 2 0 0 2 2 2 0 Surface antigen variable number repeat Curto_V3 PF07436.6 EAK89823.1 - 3.3 7.9 8.4 6.4 6.9 0.1 3.4 3 0 0 3 3 3 0 Curtovirus V3 protein Radical_SAM PF04055.16 EAK89824.1 - 1.7e-18 67.3 0.0 3.4e-18 66.3 0.0 1.5 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.15 EAK89824.1 - 6e-18 64.4 0.3 1.5e-17 63.1 0.2 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Rad4 PF03835.10 EAK89825.1 - 3.2e-16 59.0 8.5 1.5e-11 43.8 2.8 2.6 2 0 0 2 2 2 2 Rad4 transglutaminase-like domain BHD_1 PF10403.4 EAK89825.1 - 3.1e-15 55.4 1.0 5.2e-15 54.6 0.1 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EAK89825.1 - 4.6e-09 36.4 0.8 4.6e-09 36.4 0.5 2.9 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 BHD_3 PF10405.4 EAK89825.1 - 3.3e-08 33.1 0.0 8.9e-08 31.7 0.0 1.7 1 1 0 1 1 1 1 Rad4 beta-hairpin domain 3 MSG PF02349.10 EAK89825.1 - 0.0038 17.1 0.1 0.055 13.4 0.0 2.7 1 1 1 2 2 2 1 Major surface glycoprotein Transglut_core PF01841.14 EAK89825.1 - 0.12 12.6 0.1 0.45 10.7 0.0 2.0 2 0 0 2 2 2 0 Transglutaminase-like superfamily NuA4 PF09340.5 EAK89826.1 - 3.6e-26 90.5 0.1 7.8e-26 89.5 0.1 1.6 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 SLBP_RNA_bind PF15247.1 EAK89827.1 - 2.8e-17 62.2 1.6 2.8e-17 62.2 1.1 2.8 3 1 0 3 3 3 1 Histone RNA hairpin-binding protein RNA-binding domain STT3 PF02516.9 EAK89828.1 - 1.2e-78 265.2 46.7 4e-78 263.5 32.4 1.7 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Apyrase PF06079.6 EAK89829.1 - 3.1e-109 364.6 0.7 3.6e-109 364.4 0.5 1.0 1 0 0 1 1 1 1 Apyrase Reg_prop PF07494.6 EAK89829.1 - 0.0043 16.9 0.9 5.9 7.2 0.1 3.5 3 0 0 3 3 3 2 Two component regulator propeller RsgI_N PF12791.2 EAK89829.1 - 0.021 14.5 0.2 0.057 13.0 0.2 1.8 1 0 0 1 1 1 0 Anti-sigma factor N-terminus XPG_I PF00867.13 EAK89830.1 - 1.8e-23 82.3 1.0 4e-23 81.2 0.1 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EAK89830.1 - 2.6e-18 66.1 0.0 1.2e-17 64.0 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.2 EAK89830.1 - 7.8e-05 22.2 0.1 0.00017 21.1 0.1 1.5 1 0 0 1 1 1 1 XPG domain containing Prp19_bind PF06991.6 EAK89831.1 - 0.045 13.0 4.3 0.058 12.6 3.0 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain DMPK_coil PF08826.5 EAK89831.1 - 0.13 12.2 0.1 0.2 11.6 0.1 1.4 1 1 0 1 1 1 0 DMPK coiled coil domain like DUF2986 PF11661.3 EAK89831.1 - 7.8 6.9 6.8 1.7 9.0 0.2 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2986) DOT1 PF08123.8 EAK89832.1 - 6.2e-05 22.4 0.1 0.00015 21.1 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 GidB PF02527.10 EAK89832.1 - 0.029 13.5 0.0 0.067 12.3 0.0 1.6 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G HHH_5 PF14520.1 EAK89834.1 - 0.0052 16.9 0.0 2.5 8.3 0.0 3.1 2 1 0 2 2 2 2 Helix-hairpin-helix domain HHH_2 PF12826.2 EAK89834.1 - 0.054 13.3 0.0 3.8 7.4 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix motif TSP_1 PF00090.14 EAK89835.1 - 3.7e-06 26.9 39.8 4.2e-06 26.7 1.9 5.2 4 1 0 4 4 4 3 Thrombospondin type 1 domain hEGF PF12661.2 EAK89835.1 - 1.2 9.4 9.9 0.15 12.2 1.5 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF RRM_6 PF14259.1 EAK89836.1 - 5e-05 23.1 0.1 0.0021 17.9 0.0 3.2 3 1 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAK89836.1 - 5e-05 22.8 0.1 1.5 8.5 0.0 3.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK89836.1 - 0.00011 21.9 0.2 0.088 12.6 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DASH_Dam1 PF08653.5 EAK89837.1 - 4.2 7.2 13.4 1.5 8.6 0.3 4.8 5 0 0 5 5 5 0 DASH complex subunit Dam1 zf-primase PF09329.6 EAK89838.1 - 1.7e-14 53.1 1.8 1.7e-14 53.1 1.2 2.1 2 0 0 2 2 2 1 Primase zinc finger DUF3131 PF11329.3 EAK89838.1 - 0.1 11.2 0.1 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) RRM_1 PF00076.17 EAK89839.1 - 1.3e-13 50.3 0.0 2.1e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK89839.1 - 4.5e-11 42.5 0.0 7.3e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK89839.1 - 2.3e-08 33.7 0.0 3.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LicD PF04991.8 EAK89840.1 - 1.8 8.6 7.9 2.9 7.9 5.4 1.3 1 1 0 1 1 1 0 LicD family zf-CCCH PF00642.19 EAK89841.1 - 1.7e-05 24.3 17.3 0.00012 21.6 1.8 4.0 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EAK89841.1 - 0.022 14.7 4.6 0.022 14.7 3.2 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type PI3_PI4_kinase PF00454.22 EAK89842.1 - 1.5e-13 50.7 0.5 4.7e-13 49.1 0.3 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EAK89842.1 - 1.4e-09 37.4 0.8 1.4e-09 37.4 0.6 5.1 6 0 0 6 6 6 2 FAT domain FATC PF02260.15 EAK89842.1 - 0.00037 19.8 0.4 0.0029 16.9 0.0 2.6 2 0 0 2 2 2 1 FATC domain PI3_PI4_kinase PF00454.22 EAK89843.1 - 2.2e-34 118.9 0.1 1.2e-32 113.2 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EAK89843.1 - 3.9e-23 81.5 1.5 1.3e-22 79.8 1.0 1.8 1 1 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4274 PF14096.1 EAK89843.1 - 0.053 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) Prenyltrans PF00432.16 EAK89844.1 - 4.4e-37 125.3 13.1 1.1e-11 44.0 0.3 5.5 7 0 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EAK89844.1 - 3.1e-21 75.8 0.0 1.2e-11 44.9 0.0 3.6 1 1 3 4 4 4 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EAK89844.1 - 6.4e-07 29.3 0.0 0.00096 19.1 0.0 2.7 1 1 2 3 3 3 3 Prenyltransferase-like A2M_comp PF07678.9 EAK89844.1 - 7.5e-05 22.0 0.0 0.004 16.4 0.0 2.6 2 1 1 3 3 3 1 A-macroglobulin complement component EGF_CA PF07645.10 EAK89844.1 - 5.4 7.1 7.7 3.3 7.7 0.2 2.5 2 0 0 2 2 2 0 Calcium-binding EGF domain DUF3546 PF12066.3 EAK89845.1 - 2e-29 101.7 0.2 2e-29 101.7 0.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EAK89845.1 - 6.6e-07 29.7 2.3 2e-06 28.1 1.6 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 zf-C2H2_4 PF13894.1 EAK89845.1 - 0.044 14.1 1.1 0.4 11.1 0.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Ribosomal_L37ae PF01780.14 EAK89845.1 - 0.053 13.4 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family zf-C2H2 PF00096.21 EAK89845.1 - 0.42 11.0 3.5 0.65 10.4 0.8 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DEAD PF00270.24 EAK89846.1 - 2.5e-25 88.9 0.0 5e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK89846.1 - 1.6e-18 66.3 0.1 3.1e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAK89846.1 - 4.3e-06 26.6 0.0 1.5e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Acetyltransf_1 PF00583.19 EAK89847.1 - 1.6e-07 31.2 0.0 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EAK89847.1 - 0.003 17.7 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EAK89847.1 - 0.017 15.2 0.1 0.035 14.2 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DXPR_C PF13288.1 EAK89848.1 - 0.021 14.8 0.1 0.069 13.1 0.0 1.8 1 0 0 1 1 1 0 DXP reductoisomerase C-terminal domain HEAT PF02985.17 EAK89848.1 - 0.079 13.0 0.0 52 4.3 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat D123 PF07065.9 EAK89850.1 - 6.3e-68 229.0 1.6 1.1e-66 225.0 1.1 2.1 1 1 0 1 1 1 1 D123 DUF21 PF01595.15 EAK89851.1 - 6.8e-37 126.5 3.5 1.1e-36 125.8 2.4 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EAK89851.1 - 0.0051 16.5 0.7 0.32 10.8 0.0 3.1 2 2 1 3 3 3 1 CBS domain DUF3796 PF12676.2 EAK89852.1 - 0.036 14.2 2.4 0.053 13.7 1.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3796) BCIP PF13862.1 EAK89853.1 - 1.5e-42 145.3 1.5 2.1e-42 144.8 1.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Inhibitor_I42 PF09394.5 EAK89854.1 - 2.5e-20 72.6 0.1 3.3e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 HALZ PF02183.13 EAK89855.1 - 0.0041 16.8 7.9 0.0041 16.8 5.5 3.7 3 0 0 3 3 3 1 Homeobox associated leucine zipper DUF869 PF05911.6 EAK89855.1 - 0.036 12.3 29.6 0.063 11.5 20.5 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF4164 PF13747.1 EAK89855.1 - 0.086 12.9 7.0 1.5 9.0 2.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ORC3_N PF07034.6 EAK89856.1 - 1.8e-07 30.4 9.6 3.9e-07 29.3 0.1 3.0 3 0 0 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus DUF4004 PF13171.1 EAK89858.1 - 0.11 12.6 3.5 0.44 10.6 2.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4004) Glycos_transf_2 PF00535.21 EAK89861.1 - 7.3e-18 64.8 0.0 2.1e-17 63.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.9 EAK89861.1 - 2.3e-05 23.7 0.3 6.3e-05 22.3 0.2 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 EAK89861.1 - 0.00043 20.1 0.0 0.00096 19.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.17 EAK89861.1 - 0.0054 16.7 0.1 0.0054 16.7 0.0 4.0 5 0 0 5 5 5 1 Ricin-type beta-trefoil lectin domain GlcNAc PF11397.3 EAK89861.1 - 0.019 14.0 0.2 0.066 12.3 0.2 1.7 2 0 0 2 2 2 0 Glycosyltransferase (GlcNAc) Wzy_C PF04932.10 EAK89861.1 - 0.61 9.8 8.3 0.29 10.9 3.0 2.1 1 1 1 2 2 2 0 O-Antigen ligase Methyltransf_10 PF05971.7 EAK89862.1 - 4.3e-59 200.1 6.9 9.5e-38 130.0 0.7 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF890) Not1 PF04054.10 EAK89864.1 - 1.1e-106 356.8 12.1 6.7e-60 202.9 0.4 3.5 3 0 0 3 3 3 2 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EAK89864.1 - 8.4e-50 168.2 0.2 4.1e-49 166.0 0.1 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) DEAD_assoc PF08494.6 EAK89864.1 - 0.11 12.1 0.0 0.86 9.3 0.0 2.3 2 0 0 2 2 2 0 DEAD/H associated XRN_N PF03159.13 EAK89865.1 - 3.2e-89 298.3 0.1 8.1e-89 297.0 0.0 1.7 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus LRR_7 PF13504.1 EAK89866.1 - 0.049 13.8 1.0 1.8 9.0 0.0 4.1 2 0 0 2 2 2 0 Leucine rich repeat Terpene_synth_C PF03936.11 EAK89867.1 - 0.0091 15.2 0.1 0.038 13.2 0.0 2.0 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Ribosomal_L5_C PF00673.16 EAK89870.1 - 4.2e-24 84.1 0.0 6.6e-24 83.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EAK89870.1 - 3.5e-19 68.3 0.7 1.5e-18 66.2 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 RabGAP-TBC PF00566.13 EAK89871.1 - 2.2e-57 193.9 4.1 3.4e-57 193.3 2.8 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRR_8 PF13855.1 EAK89872.1 - 6.6e-09 35.4 10.2 0.0004 20.0 0.7 5.7 3 2 4 7 7 7 3 Leucine rich repeat LRR_4 PF12799.2 EAK89872.1 - 0.00018 21.0 2.7 0.00018 21.0 1.9 6.6 3 2 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EAK89872.1 - 0.009 15.9 35.3 1.3 9.3 0.1 9.1 9 1 0 9 9 9 5 Leucine Rich Repeat LRR_6 PF13516.1 EAK89872.1 - 3.6 7.9 33.5 0.37 10.9 0.5 8.4 9 0 0 9 9 9 0 Leucine Rich repeat DUF3273 PF11677.3 EAK89873.1 - 8.3e-87 290.7 9.0 9.4e-87 290.6 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF3273 PF11677.3 EAK89874.1 - 1.6e-65 221.0 12.0 2e-65 220.6 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Diphthamide_syn PF01866.12 EAK89875.1 - 3.1e-64 217.1 0.1 6.5e-64 216.0 0.1 1.5 1 1 0 1 1 1 1 Putative diphthamide synthesis protein PHD PF00628.24 EAK89876.1 - 2.2e-05 24.0 7.1 8.1e-05 22.2 4.9 2.1 1 1 0 1 1 1 1 PHD-finger DEAD PF00270.24 EAK89877.1 - 1.6e-39 135.1 0.2 1.2e-38 132.2 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK89877.1 - 1.5e-18 66.3 0.1 4.6e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EAK89877.1 - 1.1e-13 50.4 0.1 2.6e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.1 EAK89877.1 - 0.067 13.3 1.4 0.37 10.9 0.0 2.9 4 0 0 4 4 4 0 AAA domain PIG-X PF08320.7 EAK89879.1 - 0.00013 21.3 0.4 0.007 15.6 0.3 2.5 1 1 0 1 1 1 1 PIG-X / PBN1 Exo_endo_phos PF03372.18 EAK89880.1 - 4.3e-16 59.6 0.1 3.1e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family PAN_4 PF14295.1 EAK89882.1 - 0.0021 17.7 0.4 0.0059 16.2 0.3 1.8 1 0 0 1 1 1 1 PAN domain Whib PF02467.11 EAK89882.1 - 0.017 15.4 0.9 5.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Transcription factor WhiB MFS_1 PF07690.11 EAK89884.1 - 1.6e-05 23.8 35.0 1.6e-05 23.8 24.2 3.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Mito_carr PF00153.22 EAK89885.1 - 8.5e-32 108.7 3.1 1.5e-14 53.4 0.2 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Keratin_assoc PF09775.4 EAK89885.1 - 0.014 14.9 0.3 0.041 13.4 0.2 1.9 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Thia_YuaJ PF09515.5 EAK89885.1 - 0.052 13.3 5.2 0.056 13.2 0.2 2.4 2 1 0 2 2 2 0 Thiamine transporter protein (Thia_YuaJ) Mito_carr PF00153.22 EAK89886.1 - 2e-12 46.6 0.0 2.8e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein Sec1 PF00995.18 EAK89887.1 - 5.5e-62 210.1 5.3 7.3e-62 209.7 3.7 1.1 1 0 0 1 1 1 1 Sec1 family Geminin PF07412.7 EAK89887.1 - 0.085 12.5 0.6 0.17 11.5 0.4 1.4 1 0 0 1 1 1 0 Geminin NAC PF01849.13 EAK89888.1 - 2.9e-18 65.1 0.0 8.1e-18 63.7 0.0 1.8 1 0 0 1 1 1 1 NAC domain MAGE PF01454.14 EAK89888.1 - 0.017 14.4 0.1 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 MAGE family LpxD PF04613.9 EAK89888.1 - 0.14 11.7 0.0 0.85 9.1 0.0 2.1 2 0 0 2 2 2 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD SRR1 PF07985.7 EAK89889.1 - 6e-08 32.4 0.0 1.4e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 SRR1 Far-17a_AIG1 PF04750.9 EAK89890.1 - 0.00021 20.5 18.5 0.00034 19.8 12.7 1.4 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein FAST_1 PF06743.10 EAK89890.1 - 0.041 13.5 0.4 0.13 12.0 0.1 1.9 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Phosphorylase PF00343.15 EAK89891.1 - 2e-299 994.6 0.8 2.3e-299 994.3 0.6 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Ribosomal_L21e PF01157.13 EAK89892.1 - 3.4e-36 123.0 2.0 4.5e-36 122.6 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_replicase_B PF03431.8 EAK89892.1 - 0.015 13.5 0.0 0.017 13.3 0.0 1.0 1 0 0 1 1 1 0 RNA replicase, beta-chain SLA_LP_auto_ag PF05889.8 EAK89892.1 - 0.069 11.6 0.0 0.083 11.3 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Evr1_Alr PF04777.8 EAK89893.1 - 1.5e-09 37.5 0.3 8.2e-09 35.2 0.1 2.3 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.15 EAK89893.1 - 9.5e-07 28.4 0.0 2.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EAK89893.1 - 0.00091 18.9 0.0 0.0033 17.1 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family DSBA PF01323.15 EAK89893.1 - 0.21 11.1 0.1 0.34 10.4 0.1 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Ion_trans PF00520.26 EAK89895.1 - 5.7e-05 22.4 2.7 5.7e-05 22.4 1.8 1.8 2 0 0 2 2 2 1 Ion transport protein DUF1422 PF07226.6 EAK89895.1 - 0.038 13.7 1.2 0.063 13.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) Flu_NS2 PF00601.14 EAK89895.1 - 0.13 12.5 0.5 0.2 11.8 0.3 1.4 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) NAD4L PF06235.6 EAK89895.1 - 0.47 10.2 9.1 1 9.2 0.8 2.1 1 1 1 2 2 2 0 NADH dehydrogenase subunit 4L (NAD4L) DUF1211 PF06736.6 EAK89895.1 - 1.1 9.4 4.5 1.8 8.7 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1211) PPTA PF01239.17 EAK89896.1 - 2.2e-38 127.9 22.5 1.6e-09 36.6 0.3 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat RIH_assoc PF08454.6 EAK89896.1 - 0.057 13.0 0.1 0.32 10.6 0.0 2.3 2 0 0 2 2 2 0 RyR and IP3R Homology associated Rpr2 PF04032.11 EAK89897.1 - 2.1e-11 43.5 3.6 4.5e-11 42.4 2.5 1.6 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-UDP PF14569.1 EAK89897.1 - 0.11 12.3 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger Nucleoporin_FG PF13634.1 EAK89898.1 - 0.049 13.8 129.4 95 3.2 1.4 7.6 2 1 1 3 3 3 0 Nucleoporin FG repeat region MORN PF02493.15 EAK89899.1 - 8.8e-96 308.2 95.2 2.5e-09 36.2 1.6 14.8 15 0 0 15 15 15 14 MORN repeat PMR5N PF14416.1 EAK89899.1 - 8.9 6.4 15.7 33 4.6 0.1 6.2 5 1 2 7 7 7 0 PMR5 N terminal Domain Flagellin_C PF00700.16 EAK89900.1 - 0.13 12.4 0.1 0.13 12.4 0.1 3.9 5 1 1 6 6 6 0 Bacterial flagellin C-terminal helical region MOZ_SAS PF01853.13 EAK89901.1 - 8.7e-72 240.3 1.3 3.7e-71 238.2 0.9 1.9 1 1 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EAK89901.1 - 6.1e-14 51.4 0.2 1.7e-13 50.0 0.1 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Prenyltrans_2 PF13249.1 EAK89902.1 - 0.049 14.0 3.1 0.13 12.7 0.7 2.6 2 0 0 2 2 2 0 Prenyltransferase-like Ribosomal_60s PF00428.14 EAK89902.1 - 0.37 11.2 20.0 1.7 9.1 6.3 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Chorion_2 PF03964.10 EAK89902.1 - 0.84 10.2 12.5 1.9 9.0 2.1 3.0 2 0 0 2 2 2 0 Chorion family 2 Prenyltrans_1 PF13243.1 EAK89902.1 - 1.3 9.0 5.2 0.71 9.9 0.1 2.8 3 0 0 3 3 3 0 Prenyltransferase-like MFS_1 PF07690.11 EAK89906.1 - 0.00044 19.0 23.3 0.00044 19.0 16.2 2.9 1 1 1 3 3 3 2 Major Facilitator Superfamily FKBP_C PF00254.23 EAK89907.1 - 8.1e-16 57.8 0.0 1.6e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.13 EAK89907.1 - 5.7e-08 32.8 0.2 9.4e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase NTP_transf_2 PF01909.18 EAK89908.1 - 0.00018 21.7 0.3 0.00082 19.6 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyltransferase domain Inhibitor_I34 PF10466.4 EAK89910.1 - 0.35 10.9 4.0 0.58 10.2 0.8 2.3 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 Nop14 PF04147.7 EAK89911.1 - 0.09 10.6 15.3 0.11 10.4 10.6 1.0 1 0 0 1 1 1 0 Nop14-like family Astro_capsid PF03115.9 EAK89911.1 - 1.5 7.0 6.7 1.8 6.7 4.6 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Hid1 PF12722.2 EAK89911.1 - 3.2 5.3 13.6 4.5 4.8 9.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRN3 PF05327.6 EAK89914.1 - 1.3e-14 53.2 6.7 1.3e-14 53.2 4.7 1.7 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 TraH_2 PF06871.6 EAK89914.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 TraH_2 Methyltransf_18 PF12847.2 EAK89915.1 - 3.9e-15 56.3 0.0 1.8e-12 47.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EAK89915.1 - 2.4e-14 53.2 3.7 7.9e-09 35.2 0.1 2.6 2 0 0 2 2 2 2 Methyltransferase domain Spermine_synth PF01564.12 EAK89915.1 - 2.9e-09 36.2 0.1 3.7e-07 29.3 0.1 2.3 2 0 0 2 2 2 2 Spermine/spermidine synthase Methyltransf_12 PF08242.7 EAK89915.1 - 6.8e-09 36.1 0.4 4.7e-06 27.0 0.0 3.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAK89915.1 - 1e-07 32.2 0.0 0.0038 17.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EAK89915.1 - 1.8e-06 28.3 0.0 0.0012 19.2 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 EAK89915.1 - 4.1e-06 26.2 0.0 0.026 13.8 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase small domain Methyltransf_23 PF13489.1 EAK89915.1 - 0.00024 20.8 0.0 0.005 16.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EAK89915.1 - 0.00058 19.5 0.0 0.23 11.1 0.0 2.8 2 1 0 2 2 2 2 Methyltransferase domain zf-met PF12874.2 EAK89916.1 - 5.3e-06 26.4 3.3 5.3e-06 26.4 0.8 2.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EAK89916.1 - 0.05 13.7 2.5 0.82 9.8 0.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 EAK89916.1 - 2.8 7.5 5.1 1.9 8.0 0.2 2.4 2 0 0 2 2 2 0 U1 zinc finger zf-C2H2_jaz PF12171.3 EAK89916.1 - 3.5 7.8 7.6 1.7 8.8 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CENP-F_leu_zip PF10473.4 EAK89918.1 - 0.011 15.5 7.3 0.011 15.5 5.0 6.2 4 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exostosin PF03016.10 EAK89923.1 - 4.7e-09 35.7 0.0 5.5e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Exostosin family Glyco_trans_4_2 PF13477.1 EAK89923.1 - 0.025 14.4 0.2 0.054 13.3 0.2 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like Longin PF13774.1 EAK89923.1 - 0.033 13.7 0.1 0.064 12.8 0.1 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain DUF4363 PF14276.1 EAK89924.1 - 0.0072 16.0 1.7 0.014 15.0 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4363) DUF489 PF04356.7 EAK89924.1 - 0.032 13.8 0.3 0.051 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Cast PF10174.4 EAK89924.1 - 0.85 7.5 4.3 1.1 7.2 3.0 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone FeoC PF09012.5 EAK89926.1 - 0.1 12.3 0.1 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 FeoC like transcriptional regulator Bax1-I PF01027.15 EAK89928.1 - 1.5e-26 93.2 29.4 1.9e-26 92.9 20.4 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2527 PF10736.4 EAK89928.1 - 0.13 11.9 1.1 0.27 10.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) tRNA-synt_1b PF00579.20 EAK89929.1 - 1.6e-54 185.0 0.0 2e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF2013 PF09431.5 EAK89930.1 - 0.0012 18.5 0.4 0.002 17.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Folate_rec PF03024.9 EAK89931.1 - 3e-24 85.5 11.3 3.8e-24 85.1 7.8 1.1 1 0 0 1 1 1 1 Folate receptor family RCC1 PF00415.13 EAK89933.1 - 1.1e-31 108.7 0.1 8.1e-11 41.9 0.0 6.5 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EAK89933.1 - 3.9e-23 80.4 15.6 2.6e-05 23.7 0.3 5.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RPAP3_C PF13877.1 EAK89934.1 - 6.5e-08 32.4 3.5 2.3e-07 30.6 2.4 2.0 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_11 PF13414.1 EAK89934.1 - 4.1e-06 26.3 0.5 1.2e-05 24.9 0.2 1.9 2 0 0 2 2 2 1 TPR repeat N6_N4_Mtase PF01555.13 EAK89934.1 - 0.0015 18.0 1.8 0.0039 16.7 1.0 2.0 1 1 1 2 2 2 1 DNA methylase TPR_12 PF13424.1 EAK89934.1 - 0.0034 17.2 0.0 0.62 10.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAK89934.1 - 0.019 14.5 0.6 0.32 10.6 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PH PF00169.24 EAK89934.1 - 0.034 14.3 0.4 0.17 12.1 0.3 2.2 1 1 0 1 1 1 0 PH domain DUF3048 PF11258.3 EAK89934.1 - 0.062 12.4 0.4 0.11 11.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) DUF4119 PF13494.1 EAK89934.1 - 0.18 11.7 9.3 0.24 11.4 0.8 3.0 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF4119) TPR_2 PF07719.12 EAK89934.1 - 0.19 11.7 1.5 0.99 9.4 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4029 PF13221.1 EAK89934.1 - 0.86 10.0 7.5 1.8 9.0 3.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4029) TMEM154 PF15102.1 EAK89936.1 - 0.024 14.3 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF2890 PF11081.3 EAK89936.1 - 0.087 12.8 7.4 0.11 12.5 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Rhodanese PF00581.15 EAK89940.1 - 0.00057 20.2 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Mucin PF01456.12 EAK89942.1 - 5.5 6.7 14.4 12 5.6 10.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Rad9 PF04139.8 EAK89943.1 - 8.4e-13 48.0 0.3 1.6e-12 47.1 0.2 1.5 1 1 0 1 1 1 1 Rad9 Sec7 PF01369.15 EAK89944.1 - 1.8e-50 171.2 1.2 7.3e-50 169.2 0.8 2.1 1 0 0 1 1 1 1 Sec7 domain RabGAP-TBC PF00566.13 EAK89944.1 - 1.8e-25 89.7 9.1 1.8e-25 89.7 6.3 2.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain INCENP_ARK-bind PF03941.10 EAK89945.1 - 0.0012 18.6 2.0 0.0071 16.1 1.4 2.4 1 1 0 1 1 1 1 Inner centromere protein, ARK binding region NESP55 PF06390.7 EAK89945.1 - 1.8 7.8 7.4 3.9 6.7 5.1 1.5 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Sel1 PF08238.7 EAK89946.1 - 4.1e-32 109.8 15.4 5.3e-10 39.5 0.2 9.5 10 0 0 10 10 10 8 Sel1 repeat Ras PF00071.17 EAK89947.1 - 4.3e-67 224.5 0.7 5e-67 224.3 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAK89947.1 - 2.5e-21 76.3 0.0 3.8e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAK89947.1 - 1.2e-17 63.7 0.2 1.4e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAK89947.1 - 3.8e-08 32.7 0.1 4.5e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EAK89947.1 - 1.1e-06 28.2 0.2 2.4e-06 27.1 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EAK89947.1 - 7.1e-05 22.7 0.1 0.00015 21.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EAK89947.1 - 9.8e-05 21.6 0.1 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EAK89947.1 - 0.00033 19.8 0.0 0.0032 16.6 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EAK89947.1 - 0.00043 20.4 0.0 0.00062 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EAK89947.1 - 0.01 15.7 0.2 0.025 14.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAK89947.1 - 0.013 15.4 0.1 0.049 13.6 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.13 EAK89947.1 - 0.019 14.2 0.1 0.28 10.4 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_5 PF07728.9 EAK89947.1 - 0.044 13.5 0.0 0.077 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EAK89947.1 - 0.045 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EAK89947.1 - 0.06 12.9 0.9 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain NAGLU PF05089.7 EAK89947.1 - 0.084 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain G-alpha PF00503.15 EAK89947.1 - 0.086 11.5 3.6 1.4 7.4 0.3 2.8 1 1 1 2 2 2 0 G-protein alpha subunit AAA PF00004.24 EAK89947.1 - 0.13 12.5 0.1 1 9.5 0.0 2.2 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EAK89948.1 - 7e-40 136.2 0.1 1.7e-39 135.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK89948.1 - 6.3e-26 90.0 0.0 1.4e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAK89948.1 - 3.1e-05 23.9 0.1 7e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EAK89948.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain Nol1_Nop2_Fmu PF01189.12 EAK89949.1 - 2e-84 283.3 0.0 2.6e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EAK89949.1 - 0.0014 18.6 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Gpi16 PF04113.9 EAK89950.1 - 7.1e-17 60.6 4.0 4.4e-12 44.8 0.1 2.1 2 0 0 2 2 2 2 Gpi16 subunit, GPI transamidase component CppA_N PF14506.1 EAK89951.1 - 0.033 13.8 3.6 0.079 12.6 2.5 1.6 1 0 0 1 1 1 0 CppA N-terminal DUF3450 PF11932.3 EAK89951.1 - 0.61 9.3 8.7 0.84 8.8 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TPX2_importin PF12214.3 EAK89951.1 - 9.6 6.2 17.4 3.3 7.7 9.9 1.7 1 1 1 2 2 2 0 Cell cycle regulated microtubule associated protein JAB PF01398.16 EAK89953.1 - 2.6e-34 117.3 0.2 5.4e-34 116.3 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EAK89953.1 - 1.2e-18 67.2 1.2 2.6e-18 66.1 0.8 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EAK89953.1 - 8.8e-11 41.3 0.0 1.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EAK89953.1 - 0.093 12.2 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Alpha-amylase_C PF02806.13 EAK89954.1 - 3.9e-19 68.5 0.1 4.5e-18 65.1 0.1 2.7 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.13 EAK89954.1 - 6e-19 67.8 0.3 4.2e-18 65.1 0.1 2.5 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.19 EAK89954.1 - 5.4e-15 55.5 0.2 1.9e-11 43.9 0.0 3.4 2 1 0 2 2 2 1 Alpha amylase, catalytic domain RNA_pol_Rpb1_5 PF04998.12 EAK89955.1 - 7.9e-96 320.5 0.0 2.4e-95 318.9 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EAK89955.1 - 8.7e-71 238.9 0.0 8.7e-71 238.9 0.0 3.2 2 1 1 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EAK89955.1 - 4.5e-68 228.3 0.0 1.6e-67 226.5 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EAK89955.1 - 1.6e-36 125.4 0.0 6.4e-36 123.4 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EAK89955.1 - 3.3e-30 104.0 0.0 2.1e-29 101.3 0.0 2.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Phage_portal PF04860.7 EAK89956.1 - 0.0083 14.8 2.1 0.0097 14.6 1.1 1.4 1 1 0 1 1 1 1 Phage portal protein CAF-1_p150 PF11600.3 EAK89956.1 - 0.052 12.9 26.5 0.063 12.6 18.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2362 PF10154.4 EAK89956.1 - 0.071 11.7 7.6 0.087 11.4 5.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Exonuc_VII_L PF02601.10 EAK89956.1 - 0.2 10.8 6.7 0.24 10.5 4.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.11 EAK89956.1 - 0.33 9.4 3.3 0.38 9.2 2.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ATP11 PF06644.6 EAK89956.1 - 0.38 10.2 10.3 0.55 9.6 7.2 1.2 1 0 0 1 1 1 0 ATP11 protein Condensation PF00668.15 EAK89956.1 - 0.4 9.4 3.5 0.53 9.0 2.4 1.1 1 0 0 1 1 1 0 Condensation domain DUF4407 PF14362.1 EAK89956.1 - 0.54 9.1 5.6 0.63 8.9 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.12 EAK89956.1 - 1.2 8.8 6.8 1.4 8.6 4.7 1.1 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.1 EAK89956.1 - 2.7 7.4 7.6 3.4 7.1 5.3 1.2 1 0 0 1 1 1 0 AAA domain Tox-ODYAM1 PF15642.1 EAK89956.1 - 2.8 6.5 9.7 3.6 6.1 6.8 1.3 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Atg14 PF10186.4 EAK89956.1 - 3.1 6.6 12.0 3.9 6.3 8.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MAS20 PF02064.10 EAK89956.1 - 4.2 7.2 13.1 1e+02 2.8 9.0 2.4 1 1 0 1 1 1 0 MAS20 protein import receptor TMPIT PF07851.8 EAK89956.1 - 5.7 5.8 9.4 7.8 5.4 6.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein APG6 PF04111.7 EAK89956.1 - 6.6 5.6 18.4 8.6 5.3 12.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 PUB PF09409.5 EAK89957.1 - 0.0024 17.5 0.2 0.0033 17.1 0.1 1.3 1 0 0 1 1 1 1 PUB domain DUF3741 PF12552.3 EAK89957.1 - 0.14 11.9 0.0 0.14 11.9 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3741) Glyco_transf_34 PF05637.7 EAK89958.1 - 0.0042 16.6 1.3 0.0042 16.6 0.9 2.1 2 1 0 2 2 2 1 galactosyl transferase GMA12/MNN10 family Ribosomal_L32e PF01655.13 EAK89959.1 - 1.8e-46 156.7 0.7 2.3e-46 156.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Epsilon_antitox PF08998.6 EAK89960.1 - 0.0039 17.1 1.2 0.0057 16.5 0.8 1.3 1 0 0 1 1 1 1 Bacterial epsilon antitoxin FYVE PF01363.16 EAK89960.1 - 1.4 8.8 15.7 9.1 6.2 10.9 2.3 1 1 0 1 1 1 0 FYVE zinc finger NLE PF08154.7 EAK89961.1 - 4.5e-17 61.8 0.1 1.2e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 NLE (NUC135) domain WD40 PF00400.27 EAK89961.1 - 1.2e-08 34.5 6.8 0.04 13.8 0.2 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat PI3_PI4_kinase PF00454.22 EAK89962.1 - 1e-25 90.6 1.0 5.4e-25 88.2 0.3 2.6 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Spc97_Spc98 PF04130.8 EAK89963.1 - 1.9e-81 274.0 25.3 1.9e-81 274.0 17.5 1.9 2 0 0 2 2 2 1 Spc97 / Spc98 family Hexapep PF00132.19 EAK89964.1 - 2.9e-14 51.8 21.0 4.7e-05 22.7 2.5 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EAK89964.1 - 8e-06 25.3 20.4 0.00017 21.0 4.2 3.7 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase W2 PF02020.13 EAK89964.1 - 0.0085 16.0 0.4 0.0085 16.0 0.3 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Fucokinase PF07959.7 EAK89964.1 - 0.041 12.4 0.9 0.075 11.5 0.6 1.3 1 0 0 1 1 1 0 L-fucokinase RRM_1 PF00076.17 EAK89965.1 - 3e-12 45.9 0.1 1.1e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK89965.1 - 1.5e-09 37.6 0.0 2.5e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK89965.1 - 0.00071 19.3 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YjgP_YjgQ PF03739.9 EAK89965.1 - 0.11 11.2 3.9 0.17 10.5 2.7 1.4 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family Stk19 PF10494.4 EAK89969.1 - 4.9e-30 104.7 8.8 5.2e-28 98.1 5.4 2.3 1 1 1 2 2 2 1 Serine-threonine protein kinase 19 Peptidase_M44 PF03410.8 EAK89969.1 - 0.013 13.8 1.3 0.015 13.5 0.9 1.1 1 0 0 1 1 1 0 Protein G1 TetR_C_8 PF14278.1 EAK89969.1 - 2.5 8.5 8.3 0.79 10.1 2.1 2.5 3 1 0 3 3 3 0 Transcriptional regulator C-terminal region RNase_PH PF01138.16 EAK89972.1 - 9.9e-31 106.7 0.4 2.1e-30 105.7 0.2 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 DER1 PF04511.10 EAK89974.1 - 1.2e-34 119.5 10.3 1.2e-34 119.5 7.2 1.3 1 1 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 EAK89974.1 - 1e-05 25.5 8.0 1e-05 25.5 5.5 1.4 2 0 0 2 2 2 1 Rhomboid family Myotub-related PF06602.9 EAK89975.1 - 3e-106 355.1 0.9 1.7e-104 349.4 0.6 2.3 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EAK89975.1 - 0.0047 17.1 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EAK89975.1 - 0.012 15.2 0.4 0.077 12.5 0.0 2.5 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAK89975.1 - 0.016 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Streptin-Immun PF11083.3 EAK89976.1 - 0.043 13.8 0.5 0.043 13.8 0.3 2.9 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein PCI PF01399.22 EAK89977.1 - 3.7e-16 59.3 4.1 3.7e-16 59.3 2.8 2.5 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EAK89977.1 - 0.0023 17.6 4.6 0.0094 15.7 2.6 2.2 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 DUF2042 PF09743.4 EAK89977.1 - 0.0053 16.0 1.5 0.0053 16.0 1.1 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2042) DDRGK PF09756.4 EAK89977.1 - 0.03 13.7 1.4 0.061 12.7 1.0 1.4 1 0 0 1 1 1 0 DDRGK domain DUF2529 PF10740.4 EAK89977.1 - 0.048 13.0 1.9 0.37 10.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2529) NAD_binding_6 PF08030.7 EAK89977.1 - 0.08 12.8 1.1 0.19 11.6 0.8 1.7 1 0 0 1 1 1 0 Ferric reductase NAD binding domain CHAD PF05235.9 EAK89977.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 CHAD domain TPR_2 PF07719.12 EAK89977.1 - 2.3 8.3 6.1 28 4.9 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Rad10 PF03834.9 EAK89978.1 - 0.026 14.2 0.6 0.11 12.2 0.4 2.1 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) SF-assemblin PF06705.6 EAK89979.1 - 1.2e-38 132.6 39.2 2.6e-38 131.5 27.2 1.5 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF3832 PF12909.2 EAK89979.1 - 0.11 12.5 2.8 0.47 10.5 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3832) HSA PF07529.8 EAK89979.1 - 0.13 12.0 0.2 0.13 12.0 0.2 2.9 3 0 0 3 3 3 0 HSA E6 PF00518.12 EAK89979.1 - 0.21 11.9 1.5 0.52 10.6 1.0 1.7 1 0 0 1 1 1 0 Early Protein (E6) DUF3086 PF11285.3 EAK89979.1 - 0.33 9.7 16.9 0.055 12.2 7.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) RRF_GI PF12614.3 EAK89979.1 - 0.92 9.3 14.9 0.13 12.1 1.9 3.4 2 1 1 3 3 3 0 Ribosome recycling factor DUF4254 PF14063.1 EAK89979.1 - 1.3 8.6 13.6 0.12 12.0 3.8 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4254) DUF3584 PF12128.3 EAK89979.1 - 1.5 6.0 33.3 2.3 5.4 23.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ank_2 PF12796.2 EAK89980.1 - 4e-06 27.0 0.1 4e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAK89980.1 - 1e-05 25.6 0.0 5.6e-05 23.2 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAK89980.1 - 2.6e-05 24.0 0.0 0.025 14.8 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 EAK89980.1 - 5e-05 22.9 0.0 0.0049 16.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EAK89980.1 - 0.00011 22.6 0.1 0.046 14.2 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) DUF912 PF06024.7 EAK89980.1 - 0.0041 17.1 4.6 0.02 14.9 0.0 3.8 3 0 0 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Neur_chan_memb PF02932.11 EAK89980.1 - 4.1 7.2 14.8 0.11 12.3 2.5 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Thioredoxin PF00085.15 EAK89981.1 - 1.3e-08 34.4 0.0 1.9e-05 24.2 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin F-box PF00646.28 EAK89982.1 - 7.1e-05 22.3 0.2 0.00018 21.0 0.2 1.6 1 0 0 1 1 1 1 F-box domain Ank_2 PF12796.2 EAK89983.1 - 3.1e-26 91.5 0.2 4.1e-10 39.8 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAK89983.1 - 2.1e-15 56.7 5.0 4e-05 23.9 0.1 6.4 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 EAK89983.1 - 6.7e-14 50.8 0.7 0.0036 17.0 0.2 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EAK89983.1 - 5.6e-11 41.5 1.8 0.22 11.8 0.0 7.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EAK89983.1 - 5.4e-07 29.6 0.6 0.0016 18.5 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Baculo_PEP_C PF04513.7 EAK89984.1 - 0.038 13.8 1.5 0.73 9.6 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IMD PF08397.6 EAK89984.1 - 0.052 12.8 1.3 0.11 11.7 0.3 1.8 1 1 1 2 2 2 0 IRSp53/MIM homology domain PP_kinase_N PF13089.1 EAK89984.1 - 0.062 13.4 2.6 0.14 12.2 0.1 2.4 2 1 1 3 3 3 0 Polyphosphate kinase N-terminal domain DUF2414 PF10309.4 EAK89984.1 - 0.062 12.9 0.5 0.16 11.6 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) NAAA-beta PF15508.1 EAK89984.1 - 0.12 12.7 0.3 7.4 6.9 0.0 2.9 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF4041 PF13250.1 EAK89984.1 - 9.5 5.8 12.4 3.6 7.2 0.3 3.9 3 2 2 5 5 5 0 Domain of unknown function (DUF4041) PUB PF09409.5 EAK89985.1 - 2.3e-16 59.3 0.7 7.7e-16 57.6 0.5 2.0 1 0 0 1 1 1 1 PUB domain PAN_4 PF14295.1 EAK89986.1 - 0.0003 20.4 0.0 0.00091 18.8 0.0 1.8 1 0 0 1 1 1 1 PAN domain GYF PF02213.11 EAK89987.1 - 0.04 13.5 2.6 0.042 13.4 0.2 2.2 2 0 0 2 2 2 0 GYF domain Gp_dh_C PF02800.15 EAK89989.1 - 9.7e-69 229.8 0.0 1.3e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EAK89989.1 - 5.4e-62 208.2 0.0 8.7e-62 207.5 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EAK89989.1 - 0.093 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hexokinase_2 PF03727.11 EAK89990.1 - 6e-49 166.4 0.0 1.1e-48 165.6 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EAK89990.1 - 2.7e-46 157.5 1.3 2.9e-45 154.1 0.1 2.7 2 1 0 2 2 2 1 Hexokinase NUDIX_2 PF13869.1 EAK89991.1 - 5e-56 189.0 0.0 6.6e-56 188.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Asp PF00026.18 EAK89992.1 - 1e-73 248.3 0.0 1.4e-73 247.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAK89992.1 - 2.7e-06 27.4 0.0 1.2e-05 25.2 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EAK89992.1 - 0.002 18.5 0.0 4 8.0 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease Ribosomal_L7Ae PF01248.21 EAK89993.1 - 1.3e-24 85.4 0.2 1.7e-24 85.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EAK89993.1 - 0.035 13.9 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 Mito_carr PF00153.22 EAK89997.1 - 3.3e-40 135.6 0.0 3.7e-14 52.1 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein NuiA PF07924.6 EAK89997.1 - 0.056 13.3 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein PH PF00169.24 EAK89998.1 - 0.0023 18.0 1.2 0.0023 18.0 0.8 2.4 2 0 0 2 2 2 1 PH domain Vps54 PF07928.7 EAK90001.1 - 0.0011 19.1 2.9 0.0017 18.4 0.1 2.9 3 0 0 3 3 3 1 Vps54-like protein MutS_III PF05192.13 EAK90001.1 - 0.0099 15.6 0.7 0.33 10.7 0.1 3.0 2 1 0 2 2 2 1 MutS domain III Glutaredoxin PF00462.19 EAK90002.1 - 1.1e-15 57.2 0.0 2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin YodA PF09223.6 EAK90002.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 YodA lipocalin-like domain CTNNB1_binding PF08347.6 EAK90003.1 - 1.6 8.9 8.1 2.8 8.1 5.0 1.7 1 1 0 1 1 1 0 N-terminal CTNNB1 binding Tup_N PF08581.5 EAK90006.1 - 4 7.6 8.0 0.75 10.0 2.4 2.0 2 0 0 2 2 2 0 Tup N-terminal TrmB PF01978.14 EAK90007.1 - 0.034 13.8 0.0 0.085 12.5 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Cullin_Nedd8 PF10557.4 EAK90007.1 - 0.19 11.5 4.9 2.8 7.8 3.3 3.0 2 1 0 2 2 2 0 Cullin protein neddylation domain DUF788 PF05620.6 EAK90009.1 - 2e-15 57.0 16.5 2.4e-14 53.5 11.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF788) Selenoprotein_S PF06936.6 EAK90009.1 - 3.7 7.0 6.0 8.5 5.8 2.1 2.0 2 0 0 2 2 2 0 Selenoprotein S (SelS) NT-C2 PF10358.4 EAK90010.1 - 5e-27 94.1 0.6 7.2e-26 90.3 0.0 2.5 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins Abhydrolase_5 PF12695.2 EAK90011.1 - 1.8e-09 37.4 0.0 8.9e-09 35.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAK90011.1 - 6.2e-08 32.7 0.0 1.9e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAK90011.1 - 1.8e-06 27.6 0.1 0.00013 21.6 0.0 2.4 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EAK90011.1 - 0.0015 18.1 0.0 0.38 10.2 0.0 3.0 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EAK90011.1 - 0.012 15.0 1.4 5.3 6.4 0.0 3.2 4 0 0 4 4 4 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EAK90011.1 - 0.026 14.1 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Methyltransf_12 PF08242.7 EAK90011.1 - 0.074 13.5 0.1 0.26 11.8 0.1 1.9 1 0 0 1 1 1 0 Methyltransferase domain DUF2018 PF09442.5 EAK90012.1 - 6.4 7.4 11.1 3.5 8.2 1.2 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF2018) CIAPIN1 PF05093.8 EAK90016.1 - 1.1e-26 92.8 7.9 2.1e-26 91.9 5.5 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Ndc80_HEC PF03801.8 EAK90017.1 - 6.9e-38 129.6 0.0 3e-37 127.5 0.0 2.0 1 0 0 1 1 1 1 HEC/Ndc80p family Cluap1 PF10234.4 EAK90017.1 - 0.003 16.7 0.0 0.003 16.7 0.0 5.5 3 2 3 6 6 6 1 Clusterin-associated protein-1 bZIP_1 PF00170.16 EAK90017.1 - 0.014 15.3 4.4 0.014 15.3 3.0 5.5 5 1 1 6 6 6 0 bZIP transcription factor CitG PF01874.11 EAK90017.1 - 0.057 12.6 0.3 8.4 5.5 0.1 2.6 2 0 0 2 2 2 0 ATP:dephospho-CoA triphosphoribosyl transferase WD40 PF00400.27 EAK90018.1 - 5.4e-08 32.4 8.9 0.008 16.0 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Bromodomain PF00439.20 EAK90018.1 - 2.6e-06 27.2 0.2 9.9e-06 25.3 0.1 2.0 1 0 0 1 1 1 1 Bromodomain zf-HC5HC2H PF13771.1 EAK90018.1 - 0.00011 22.2 5.5 0.00011 22.2 3.8 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EAK90018.1 - 0.00016 21.6 1.3 0.00075 19.4 0.9 2.2 1 0 0 1 1 1 1 PHD-zinc-finger like domain EF-hand_7 PF13499.1 EAK90019.1 - 0.00018 21.5 0.0 0.00065 19.7 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EAK90019.1 - 0.00035 19.6 0.2 0.046 13.0 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EAK90019.1 - 0.0072 16.1 0.0 0.14 12.0 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain LAGLIDADG_1 PF00961.14 EAK90019.1 - 0.083 13.4 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 LAGLIDADG endonuclease Ribosomal_L16 PF00252.13 EAK90021.1 - 1.9e-31 108.5 0.1 2.3e-31 108.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Metallophos PF00149.23 EAK90022.1 - 1.5e-41 142.0 0.2 2.6e-41 141.2 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mo25 PF08569.6 EAK90023.1 - 8.7e-107 357.0 20.8 1.7e-106 356.0 14.4 1.4 1 0 0 1 1 1 1 Mo25-like ATP_bind_1 PF03029.12 EAK90025.1 - 2.3e-79 266.2 0.1 2.6e-79 266.1 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EAK90025.1 - 6.4e-06 26.9 0.0 1.5e-05 25.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAK90025.1 - 0.0041 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EAK90025.1 - 0.011 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAK90025.1 - 0.02 14.8 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EAK90025.1 - 0.021 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EAK90025.1 - 0.036 13.6 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EAK90025.1 - 0.049 13.5 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EAK90025.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EAK90025.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EAK90025.1 - 0.083 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ArgK PF03308.11 EAK90025.1 - 0.1 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 EAK90025.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain CS PF04969.11 EAK90026.1 - 1.8e-06 28.3 4.3 4e-06 27.2 2.4 2.1 1 1 0 1 1 1 1 CS domain CDC37_N PF03234.9 EAK90026.1 - 0.0028 18.0 3.2 0.0028 18.0 2.2 2.7 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding B2-adapt-app_C PF09066.5 EAK90026.1 - 0.088 12.6 0.1 0.088 12.6 0.1 2.0 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain DUF4297 PF14130.1 EAK90026.1 - 5.2 6.9 12.4 1.1 9.1 5.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4297) GAS PF13851.1 EAK90029.1 - 1.2 8.3 65.4 1.6 7.8 10.3 4.3 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EAK90029.1 - 3.9 7.0 58.5 10 5.6 4.0 4.2 2 1 1 3 3 3 0 IncA protein TRAPPC-Trs85 PF12739.2 EAK90030.1 - 1.1e-27 96.7 0.2 3e-27 95.3 0.2 1.6 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit His_Phos_1 PF00300.17 EAK90031.1 - 2e-20 73.4 0.0 3.3e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA PF00004.24 EAK90032.1 - 1.8e-40 138.1 0.0 4e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAK90032.1 - 1.6e-06 28.2 0.1 0.00018 21.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EAK90032.1 - 8.7e-06 25.5 0.0 4.1e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EAK90032.1 - 0.00013 22.8 0.1 0.00027 21.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAK90032.1 - 0.00017 21.5 0.1 0.0023 17.9 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EAK90032.1 - 0.00074 19.4 0.0 0.0029 17.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EAK90032.1 - 0.001 18.7 0.1 0.0022 17.6 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EAK90032.1 - 0.0011 18.0 0.0 0.0026 16.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EAK90032.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EAK90032.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 EAK90032.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAK90032.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EAK90032.1 - 0.021 15.1 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EAK90032.1 - 0.028 14.3 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 EAK90032.1 - 0.031 14.4 0.3 0.19 11.8 0.0 2.4 4 0 0 4 4 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IstB_IS21 PF01695.12 EAK90032.1 - 0.042 13.2 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EAK90032.1 - 0.042 13.0 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EAK90032.1 - 0.042 13.4 0.1 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EAK90032.1 - 0.055 12.1 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 EAK90032.1 - 0.064 12.6 0.0 0.9 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EAK90032.1 - 0.073 12.6 0.0 0.15 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EAK90032.1 - 0.088 12.4 0.0 12 5.5 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase Sec66 PF09802.4 EAK90033.1 - 0.0038 16.6 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 MARVEL PF01284.18 EAK90033.1 - 0.0088 15.8 10.0 0.0088 15.8 7.0 2.3 2 1 0 2 2 2 1 Membrane-associating domain YrhC PF14143.1 EAK90033.1 - 0.036 14.0 3.0 1.4 8.9 0.1 3.3 3 0 0 3 3 3 0 YrhC-like protein Rax2 PF12768.2 EAK90033.1 - 0.079 12.1 0.3 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 Cortical protein marker for cell polarity NADH-u_ox-rdase PF10785.4 EAK90033.1 - 0.16 12.2 0.2 0.16 12.2 0.1 2.7 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Adeno_E3_CR2 PF02439.10 EAK90033.1 - 0.16 11.5 0.0 0.16 11.5 0.0 3.0 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 Acyl_transf_3 PF01757.17 EAK90033.1 - 0.26 10.0 16.2 1.1 7.9 11.3 1.8 1 1 0 1 1 1 0 Acyltransferase family DUF1049 PF06305.6 EAK90033.1 - 1.1 8.8 9.2 4.6 6.8 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1049) Caa3_CtaG PF09678.5 EAK90033.1 - 1.6 7.6 8.7 0.083 11.8 2.2 1.8 2 1 0 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DUF3816 PF12822.2 EAK90033.1 - 5.1 6.9 16.6 1.2 9.0 7.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) DUF1469 PF07332.6 EAK90033.1 - 6.1 6.5 8.9 0.37 10.5 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1469) DUF4131 PF13567.1 EAK90033.1 - 8.7 5.7 12.9 0.24 10.7 1.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) RRM_1 PF00076.17 EAK90034.1 - 8e-11 41.4 0.0 1.9e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK90034.1 - 9.7e-08 31.8 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK90034.1 - 4.9e-05 23.0 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_B PF00136.16 EAK90037.1 - 9.1e-131 436.8 0.5 1.3e-130 436.3 0.3 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EAK90037.1 - 3.4e-69 233.1 0.4 5.7e-69 232.4 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EAK90037.1 - 2.9e-20 72.0 11.4 6.5e-20 70.9 7.9 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta zf-RING-like PF08746.6 EAK90037.1 - 0.56 10.2 11.2 1 9.3 0.6 2.8 2 0 0 2 2 2 0 RING-like domain Helicase_C PF00271.26 EAK90038.1 - 1.2e-22 79.5 0.3 3.6e-20 71.5 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 EAK90038.1 - 2.7e-17 62.7 0.0 1.1e-16 60.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HRDC PF00570.18 EAK90038.1 - 1.3e-08 34.4 0.0 3.3e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Myb_DNA-binding PF00249.26 EAK90042.1 - 7.4e-08 32.3 0.2 1.6e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAK90042.1 - 0.00034 20.6 0.1 0.00088 19.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Spore_YabQ PF09578.5 EAK90043.1 - 0.016 15.1 5.1 0.07 13.0 3.6 2.1 1 0 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) UCH PF00443.24 EAK90046.1 - 4.5e-47 160.4 5.0 6.9e-47 159.8 3.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAK90046.1 - 4.1e-15 55.9 19.0 6.2e-12 45.5 12.9 3.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EAK90046.1 - 4.2e-11 42.7 0.1 2e-10 40.6 0.0 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EAK90046.1 - 0.00029 20.6 0.0 0.51 10.2 0.0 2.9 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.1 EAK90046.1 - 0.0047 16.4 1.0 0.0098 15.4 0.0 2.1 3 0 0 3 3 3 1 UBA-like domain RecX PF02631.11 EAK90046.1 - 0.067 13.3 0.2 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 RecX family zf-DHHC PF01529.15 EAK90047.1 - 2.1e-35 121.6 6.8 2.1e-35 121.6 4.7 2.4 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF2207 PF09972.4 EAK90047.1 - 0.22 10.0 0.0 0.22 10.0 0.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Gln-synt_C PF00120.19 EAK90048.1 - 5.6e-83 278.0 0.0 7.5e-83 277.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EAK90048.1 - 3.7e-20 71.3 0.5 7e-20 70.3 0.3 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RNA_pol_Rpc34 PF05158.7 EAK90049.1 - 6.9e-49 166.7 3.9 1.3e-46 159.2 2.7 2.1 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 EAK90049.1 - 0.044 13.6 0.1 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC PIG-H PF10181.4 EAK90050.1 - 4.1e-15 55.1 0.5 1.1e-14 53.7 0.3 1.8 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Ribosomal_S8e PF01201.17 EAK90051.1 - 8.6e-51 171.5 0.4 1.1e-50 171.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e DUF3449 PF11931.3 EAK90054.1 - 9.1e-70 234.1 0.5 1.6e-69 233.4 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) zf-met PF12874.2 EAK90054.1 - 0.013 15.6 4.6 1.8 8.8 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EAK90054.1 - 0.49 10.6 5.0 7.4 6.8 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF972 PF06156.8 EAK90054.1 - 0.52 10.6 5.1 0.22 11.8 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Rft-1 PF04506.8 EAK90055.1 - 3.7e-29 101.5 34.4 3.7e-27 94.9 23.8 2.1 1 1 0 1 1 1 1 Rft protein SAC3_GANP PF03399.11 EAK90056.1 - 1.2e-50 171.9 3.6 2.2e-50 171.0 2.5 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EAK90056.1 - 7.9e-05 22.4 0.1 0.00023 20.9 0.1 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 RRM_1 PF00076.17 EAK90057.1 - 1e-66 220.4 4.9 3.7e-15 55.3 0.0 5.9 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK90057.1 - 4.2e-60 199.6 1.0 1.4e-14 53.7 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK90057.1 - 1.5e-41 140.0 0.9 6.2e-08 32.3 0.0 5.8 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EAK90057.1 - 0.00015 21.4 0.2 1.9 8.3 0.0 4.6 4 1 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.1 EAK90057.1 - 0.0062 16.2 0.0 8.9 6.1 0.0 3.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif SNARE_assoc PF09335.6 EAK90058.1 - 7.1e-12 45.6 6.0 7.1e-12 45.6 4.2 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF1980 PF09323.5 EAK90058.1 - 0.03 14.0 1.7 0.03 14.0 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) SF3b1 PF08920.5 EAK90059.1 - 5.6e-31 107.5 3.4 9.8e-31 106.7 2.3 1.3 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EAK90059.1 - 4.5e-17 62.1 0.2 0.24 11.7 0.0 8.5 4 3 5 9 9 9 7 HEAT repeats HEAT PF02985.17 EAK90059.1 - 1.9e-14 52.3 6.8 0.085 12.9 0.0 10.4 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 EAK90059.1 - 1.2e-12 47.8 0.5 0.16 12.5 0.0 8.6 9 1 1 10 10 10 2 HEAT-like repeat CLASP_N PF12348.3 EAK90059.1 - 1.1e-06 28.2 2.8 0.036 13.4 0.1 4.1 5 0 0 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 EAK90059.1 - 2.2e-06 27.9 0.1 0.1 12.9 0.0 4.7 4 2 0 4 4 4 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EAK90059.1 - 0.0013 17.5 4.8 0.07 11.8 0.0 4.7 6 0 0 6 6 6 1 RNAPII transcription regulator C-terminal NUC173 PF08161.7 EAK90059.1 - 0.017 14.4 0.1 7.7 5.8 0.0 3.7 3 1 0 3 3 3 0 NUC173 domain DUF4042 PF13251.1 EAK90059.1 - 0.019 14.4 0.3 9.9 5.5 0.0 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4042) TIP120 PF08623.5 EAK90059.1 - 0.087 12.4 1.0 1.5 8.3 0.0 2.9 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) SNARE_assoc PF09335.6 EAK90060.1 - 8.6e-06 25.9 2.0 8.6e-06 25.9 1.4 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein Alpha_E2_glycop PF00943.14 EAK90060.1 - 0.23 10.0 0.5 0.35 9.4 0.3 1.2 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein PAP2 PF01569.16 EAK90060.1 - 0.97 9.1 0.0 0.97 9.1 0.0 3.3 4 0 0 4 4 4 0 PAP2 superfamily NicO PF03824.11 EAK90060.1 - 5.3 6.2 8.7 0.17 11.1 0.4 2.2 2 1 1 3 3 3 0 High-affinity nickel-transport protein Adeno_E3_CR2 PF02439.10 EAK90060.1 - 6.2 6.4 8.8 0.24 10.9 0.8 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 RRM_5 PF13893.1 EAK90061.1 - 9.4e-07 28.5 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAK90061.1 - 2.9e-05 23.6 0.1 9.2e-05 22.0 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK90061.1 - 0.00046 20.1 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LETM1 PF07766.8 EAK90061.1 - 0.0015 17.6 0.6 0.0024 16.9 0.4 1.2 1 0 0 1 1 1 1 LETM1-like protein zf-CCCH PF00642.19 EAK90061.1 - 0.34 10.6 4.5 0.75 9.5 3.1 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PRA-PH PF01503.12 EAK90062.1 - 0.36 11.1 0.0 0.36 11.1 0.0 2.5 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Cytadhesin_P30 PF07271.6 EAK90062.1 - 6.3 5.9 6.0 12 5.0 4.2 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 Peptidase_S8 PF00082.17 EAK90066.1 - 3.3e-48 164.2 2.3 5.9e-48 163.4 1.6 1.4 1 0 0 1 1 1 1 Subtilase family Peptidase_C1 PF00112.18 EAK90067.1 - 9.6e-70 234.8 2.1 1.9e-69 233.9 1.4 1.5 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EAK90067.1 - 6.5e-14 51.9 11.2 7.1e-14 51.8 6.6 2.0 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EAK90067.1 - 1.7e-10 40.0 1.0 1.1e-06 27.4 0.1 2.4 2 0 0 2 2 2 2 Peptidase C1-like family 6PF2K PF01591.13 EAK90067.1 - 0.0055 15.8 3.3 0.0098 14.9 2.3 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase ABC2_membrane_3 PF12698.2 EAK90067.1 - 0.008 15.2 0.3 0.011 14.8 0.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Peptidase_C39_2 PF13529.1 EAK90067.1 - 0.015 15.6 0.0 0.038 14.3 0.0 1.9 1 0 0 1 1 1 0 Peptidase_C39 like family NVEALA PF14055.1 EAK90067.1 - 0.025 14.3 1.8 0.067 12.9 1.2 1.8 1 0 0 1 1 1 0 NVEALA protein DUF1510 PF07423.6 EAK90067.1 - 0.046 13.0 0.4 0.08 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Wzy_C PF04932.10 EAK90067.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 O-Antigen ligase CRT-like PF08627.5 EAK90068.1 - 3.2e-11 43.2 2.2 1.4e-09 37.9 0.3 3.0 3 0 0 3 3 3 1 CRT-like EamA PF00892.15 EAK90068.1 - 8e-05 22.6 21.4 0.024 14.6 5.5 3.7 3 1 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EAK90068.1 - 0.0042 15.9 8.8 0.04 12.7 4.0 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 EAK90068.1 - 0.64 9.6 25.8 3.8 7.1 9.7 3.0 2 1 0 2 2 2 0 Triose-phosphate Transporter family EmrE PF13536.1 EAK90068.1 - 1.6 8.9 23.6 0.2 11.8 3.8 3.6 3 1 1 4 4 4 0 Multidrug resistance efflux transporter Adaptin_N PF01602.15 EAK90071.1 - 7.5e-42 143.3 17.4 5.3e-41 140.5 12.0 1.9 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EAK90071.1 - 0.0064 16.4 0.0 3.4 8.0 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 EAK90071.1 - 0.011 16.0 0.0 0.28 11.4 0.0 2.1 1 1 1 2 2 2 0 HEAT repeats Cpn60_TCP1 PF00118.19 EAK90074.1 - 1e-112 377.2 4.4 1.2e-112 376.9 3.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HEAT PF02985.17 EAK90076.1 - 1.3e-15 55.9 5.9 0.11 12.6 0.0 8.0 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 EAK90076.1 - 3.1e-09 36.9 0.0 0.2 11.9 0.0 5.8 6 0 0 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 EAK90076.1 - 3.6e-06 27.2 0.0 2.8 8.5 0.0 5.2 5 0 0 5 5 5 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EAK90076.1 - 0.004 17.5 0.6 0.22 11.9 0.2 3.5 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Abhydrolase_5 PF12695.2 EAK90077.1 - 7.6e-24 84.1 0.0 1e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAK90077.1 - 1.3e-13 51.3 0.0 5.7e-12 46.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAK90077.1 - 4.8e-07 29.2 0.0 1.2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 EAK90077.1 - 5.4e-05 22.7 0.0 7.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EAK90077.1 - 0.00045 19.8 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EAK90077.1 - 0.0054 16.3 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EAK90077.1 - 0.016 14.6 0.0 3.5 7.0 0.1 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 EAK90077.1 - 0.1 11.8 0.0 0.56 9.4 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family CS PF04969.11 EAK90079.1 - 2.5e-06 27.9 0.7 2.8e-05 24.5 0.5 2.2 1 1 0 1 1 1 1 CS domain Dot_icm_IcmQ PF09475.5 EAK90079.1 - 0.052 12.7 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Ribophorin_I PF04597.9 EAK90081.1 - 2.5e-107 359.0 8.6 2.9e-107 358.8 5.9 1.0 1 0 0 1 1 1 1 Ribophorin I MNSV_P7B PF06692.6 EAK90081.1 - 0.094 12.5 1.3 1.7 8.5 0.1 2.9 2 1 1 3 3 3 0 Melon necrotic spot virus P7B protein Pkinase PF00069.20 EAK90082.1 - 3.9e-33 114.6 0.0 6.4e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK90082.1 - 2.8e-13 49.5 0.0 4.8e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAK90082.1 - 0.00026 20.0 0.0 0.00046 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EAK90082.1 - 0.037 13.3 0.4 0.075 12.3 0.0 1.7 2 0 0 2 2 2 0 RIO1 family SGT1 PF07093.6 EAK90083.1 - 5.7e-37 127.3 21.6 1.5e-36 125.9 15.0 1.5 1 1 0 1 1 1 1 SGT1 protein Lectin_leg-like PF03388.8 EAK90085.1 - 3.1e-22 78.8 0.1 6.1e-22 77.8 0.1 1.5 1 1 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EAK90085.1 - 0.0011 18.3 1.2 0.0046 16.3 0.8 2.1 1 1 0 1 1 1 1 Legume lectin domain Baculo_E56 PF04639.7 EAK90085.1 - 0.0029 16.3 3.1 0.55 8.8 0.3 2.2 2 0 0 2 2 2 2 Baculoviral E56 protein, specific to ODV envelope Glucos_trans_II PF14264.1 EAK90085.1 - 0.15 11.0 0.1 0.25 10.2 0.1 1.4 1 0 0 1 1 1 0 Glucosyl transferase GtrII Snapin_Pallidin PF14712.1 EAK90085.1 - 0.21 11.9 4.0 0.12 12.7 0.6 2.0 2 0 0 2 2 2 0 Snapin/Pallidin Met_10 PF02475.11 EAK90086.1 - 5.5e-42 143.6 0.1 9e-42 142.9 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 EAK90086.1 - 0.00034 20.2 0.7 0.0011 18.5 0.1 2.2 2 2 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EAK90086.1 - 0.00043 19.7 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EAK90086.1 - 0.00058 20.4 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAK90086.1 - 0.0018 17.4 0.0 0.0032 16.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EAK90086.1 - 0.002 18.1 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.11 EAK90086.1 - 0.04 12.8 0.1 0.078 11.8 0.1 1.4 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_23 PF13489.1 EAK90086.1 - 0.071 12.8 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain WWE PF02825.15 EAK90087.1 - 2.6e-10 39.5 13.9 3.4e-09 36.0 1.6 3.2 3 0 0 3 3 3 2 WWE domain zf-RING_2 PF13639.1 EAK90087.1 - 3.9e-10 39.3 8.0 3.9e-10 39.3 5.6 1.7 2 0 0 2 2 1 1 Ring finger domain zf-Nse PF11789.3 EAK90087.1 - 0.00014 21.3 2.3 0.00035 20.0 1.6 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.1 EAK90087.1 - 0.00033 20.6 8.6 0.00033 20.6 5.9 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) SAICAR_synt PF01259.13 EAK90087.1 - 0.0008 18.5 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 SAICAR synthetase zf-C3HC4 PF00097.20 EAK90087.1 - 0.002 17.7 9.5 0.002 17.7 6.6 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EAK90087.1 - 0.0021 18.1 7.2 0.0088 16.1 5.0 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EAK90087.1 - 0.0024 17.6 2.9 0.0057 16.4 2.0 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EAK90087.1 - 0.012 15.3 7.9 0.012 15.3 5.5 2.0 2 0 0 2 2 2 0 zinc-RING finger domain PHD PF00628.24 EAK90087.1 - 0.029 14.0 5.8 0.082 12.6 4.0 1.8 1 0 0 1 1 1 0 PHD-finger zf-Apc11 PF12861.2 EAK90087.1 - 0.053 13.3 4.2 0.25 11.2 3.0 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 EAK90087.1 - 0.47 10.2 5.9 0.2 11.4 1.6 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 EAK90087.1 - 2.2 8.0 8.3 10 5.9 5.8 2.3 1 0 0 1 1 1 0 RING-type zinc-finger CreA PF05981.7 EAK90088.1 - 0.069 12.6 0.1 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 CreA protein CAMSAP_CKK PF08683.6 EAK90089.1 - 6.6e-37 125.9 1.3 6.6e-37 125.9 0.9 1.6 2 0 0 2 2 2 1 Microtubule-binding calmodulin-regulated spectrin-associated DUF4206 PF13901.1 EAK90091.1 - 4.8e-09 36.0 8.8 7.6e-08 32.1 6.1 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4206) DUF2572 PF10833.3 EAK90092.1 - 0.085 12.2 2.8 0.052 12.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2572) TSC22 PF01166.13 EAK90092.1 - 7.2 6.6 6.1 3.6 7.6 1.3 2.6 2 1 1 3 3 3 0 TSC-22/dip/bun family Pkinase PF00069.20 EAK90093.1 - 4.6e-56 189.8 0.0 9.7e-56 188.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK90093.1 - 3e-32 111.7 0.0 4.4e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAK90093.1 - 1.2e-08 34.2 0.0 2.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAK90093.1 - 0.043 13.5 0.0 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family SH2_2 PF14633.1 EAK90094.1 - 6.4e-19 67.8 0.2 1.6e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.1 EAK90094.1 - 1.2e-11 44.5 0.0 4e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif ABC_tran PF00005.22 EAK90095.1 - 1e-46 158.6 0.1 8e-23 81.2 0.0 3.1 3 1 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EAK90095.1 - 8.5e-20 70.3 0.1 8.5e-20 70.3 0.1 2.3 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EAK90095.1 - 8e-16 58.8 23.9 4.9e-08 33.2 0.3 5.4 3 2 2 5 5 5 3 AAA domain SMC_N PF02463.14 EAK90095.1 - 1.2e-10 40.9 1.7 0.0043 16.3 0.0 3.6 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain Miro PF08477.8 EAK90095.1 - 2.5e-07 31.2 0.0 0.057 13.9 0.0 3.5 2 1 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 EAK90095.1 - 1e-05 24.7 14.8 0.17 10.8 0.1 4.8 5 0 0 5 5 5 3 AAA ATPase domain AAA_29 PF13555.1 EAK90095.1 - 1.4e-05 24.5 3.0 0.054 13.0 0.1 3.3 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EAK90095.1 - 3.3e-05 24.6 6.1 0.019 15.7 0.1 3.5 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 EAK90095.1 - 0.00016 20.9 0.1 0.48 9.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EAK90095.1 - 0.00021 21.4 3.1 0.23 11.5 0.4 3.7 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EAK90095.1 - 0.001 19.0 2.1 0.12 12.3 0.0 3.1 3 1 0 3 3 2 1 AAA ATPase domain AAA_10 PF12846.2 EAK90095.1 - 0.0015 18.0 0.2 0.42 9.9 0.1 2.8 2 0 0 2 2 2 1 AAA-like domain T2SE PF00437.15 EAK90095.1 - 0.0017 17.3 1.9 0.006 15.5 0.3 2.3 2 1 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.7 EAK90095.1 - 0.0027 17.4 1.5 2 8.0 0.4 2.7 2 0 0 2 2 2 2 NACHT domain DUF87 PF01935.12 EAK90095.1 - 0.0031 17.3 5.8 5.4 6.7 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function DUF87 SbcCD_C PF13558.1 EAK90095.1 - 0.0035 17.2 0.0 0.62 10.0 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EAK90095.1 - 0.0042 17.4 0.1 0.0042 17.4 0.0 4.4 3 1 0 3 3 2 1 AAA domain AAA_14 PF13173.1 EAK90095.1 - 0.0046 16.8 0.4 4.6 7.1 0.0 4.0 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EAK90095.1 - 0.0069 15.8 1.5 0.023 14.1 0.1 2.4 2 1 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 EAK90095.1 - 0.0086 15.9 0.1 5.4 6.8 0.0 2.8 2 1 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 EAK90095.1 - 0.0096 15.8 0.0 0.68 9.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EAK90095.1 - 0.01 15.8 2.2 0.53 10.2 0.3 3.0 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.17 EAK90095.1 - 0.011 14.5 0.1 2.4 6.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 EAK90095.1 - 0.015 15.4 0.1 6.6 6.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 EAK90095.1 - 0.016 14.9 0.9 2.5 7.8 0.2 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EAK90095.1 - 0.027 14.1 1.2 1.9 8.1 0.2 2.7 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.1 EAK90095.1 - 0.028 14.7 10.0 0.13 12.6 0.0 4.5 5 1 0 5 5 5 0 AAA domain MMR_HSR1 PF01926.18 EAK90095.1 - 0.035 14.0 0.0 2 8.3 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA PF00004.24 EAK90095.1 - 0.057 13.6 0.1 4.9 7.3 0.0 3.5 2 1 1 3 3 2 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 EAK90095.1 - 0.057 12.0 0.1 0.13 10.8 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 EAK90095.1 - 0.059 12.8 0.4 15 5.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EAK90095.1 - 0.11 11.8 0.1 18 4.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EAK90095.1 - 0.14 11.9 0.1 1.4 8.6 0.0 2.6 3 0 0 3 3 2 0 Part of AAA domain Sigma54_activat PF00158.21 EAK90095.1 - 0.18 11.2 0.8 1 8.7 0.1 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EAK90095.1 - 0.23 11.0 1.3 7.6 6.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF3901 PF13040.1 EAK90096.1 - 0.079 12.2 0.1 0.18 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3901) HEPN PF05168.9 EAK90096.1 - 0.12 12.2 1.2 0.82 9.5 0.9 2.1 1 1 0 1 1 1 0 HEPN domain P4Ha_N PF08336.6 EAK90096.1 - 0.24 11.1 2.5 1.9 8.2 1.0 2.1 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region CC2D2AN-C2 PF15625.1 EAK90098.1 - 0.12 11.7 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain HlyD_3 PF13437.1 EAK90100.1 - 0.0025 18.1 0.7 16 5.9 0.0 4.7 4 1 0 4 4 4 1 HlyD family secretion protein AP2 PF00847.15 EAK90101.1 - 3.9e-41 138.9 10.8 2.6e-11 43.5 0.0 4.4 4 0 0 4 4 4 4 AP2 domain Ribosomal_S6 PF01250.12 EAK90101.1 - 0.062 13.1 0.6 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein S6 DUF4003 PF13170.1 EAK90104.1 - 0.0094 15.2 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4003) DUF3273 PF11677.3 EAK90113.1 - 4.2e-88 295.0 12.0 4.9e-88 294.8 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) tRNA-synt_2c PF01411.14 EAK90114.1 - 2.5e-188 626.8 0.0 2.5e-188 626.8 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EAK90114.1 - 1.1e-15 57.1 2.2 1.8e-15 56.4 0.2 2.5 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain Prenyltransf PF01255.14 EAK90114.1 - 0.0052 15.9 2.1 0.014 14.5 1.4 1.7 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF3492 PF11997.3 EAK90114.1 - 0.0072 15.9 2.5 2.2 7.7 0.1 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF3492) DHHA1 PF02272.14 EAK90114.1 - 0.091 12.4 0.0 0.32 10.7 0.0 2.1 1 0 0 1 1 1 0 DHHA1 domain OrfB_IS605 PF01385.14 EAK90114.1 - 1.4 8.2 8.3 0.067 12.5 1.1 2.1 2 0 0 2 2 2 0 Probable transposase Ribosomal_L14 PF00238.14 EAK90115.1 - 3.2e-33 114.0 0.0 3.7e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF3608 PF12257.3 EAK90116.1 - 6.7e-12 44.9 8.6 6.7e-12 44.9 6.0 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3608) Elongin_A PF06881.6 EAK90116.1 - 0.033 14.5 2.7 0.13 12.6 1.9 2.0 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Got1 PF04178.7 EAK90117.1 - 6.1e-30 103.7 20.0 1e-29 103.0 13.8 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family bZIP_2 PF07716.10 EAK90118.1 - 0.00026 20.7 10.5 0.00026 20.7 7.3 2.0 2 0 0 2 2 2 1 Basic region leucine zipper CENP-F_leu_zip PF10473.4 EAK90118.1 - 0.0063 16.3 6.3 0.016 15.0 4.4 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 EAK90118.1 - 0.034 14.0 8.7 0.13 12.2 6.0 2.0 1 0 0 1 1 1 0 bZIP transcription factor Thioredoxin PF00085.15 EAK90119.1 - 9.1e-27 92.7 0.2 3.5e-26 90.8 0.4 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 EAK90119.1 - 0.0003 20.8 0.6 0.0016 18.5 0.1 2.4 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EAK90119.1 - 0.0013 18.9 0.5 0.0065 16.6 0.3 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EAK90119.1 - 0.062 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin DnaJ PF00226.26 EAK90120.1 - 1e-18 66.8 0.4 2.6e-18 65.4 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain P-mevalo_kinase PF04275.9 EAK90120.1 - 0.0057 16.3 0.6 0.018 14.7 0.2 2.0 2 0 0 2 2 2 1 Phosphomevalonate kinase TP_methylase PF00590.15 EAK90121.1 - 1.2e-18 67.6 0.0 2.9e-18 66.3 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases BHD_1 PF10403.4 EAK90121.1 - 0.044 13.2 0.0 0.095 12.2 0.0 1.6 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 Acyltransferase PF01553.16 EAK90122.1 - 1.5e-16 60.0 0.0 1.3e-15 57.0 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase zf-CCCH PF00642.19 EAK90123.1 - 4.2e-09 35.8 8.9 9.8e-05 21.9 0.0 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EAK90123.1 - 0.0069 16.3 2.7 0.47 10.5 0.2 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type Hist_deacetyl PF00850.14 EAK90124.1 - 1.7e-74 250.9 0.1 2.2e-74 250.5 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain PS_pyruv_trans PF04230.8 EAK90125.1 - 1e-21 77.9 2.4 1e-21 77.9 1.6 1.9 2 0 0 2 2 2 1 Polysaccharide pyruvyl transferase Fringe PF02434.11 EAK90125.1 - 2.5e-19 69.4 0.1 5.7e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 EAK90125.1 - 8.7e-11 41.7 0.0 2.8e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Galactosyltransferase DUF572 PF04502.8 EAK90127.1 - 5.3e-51 173.7 6.8 7.3e-51 173.2 4.7 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF3797 PF12677.2 EAK90127.1 - 0.026 14.1 0.4 0.081 12.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) DNA_RNApol_7kD PF03604.8 EAK90127.1 - 0.45 10.0 3.0 1.1 8.7 0.1 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit BT1 PF03092.11 EAK90128.1 - 1e-51 176.0 10.7 2e-51 175.1 7.4 1.3 1 1 0 1 1 1 1 BT1 family DUF2367 PF10164.4 EAK90128.1 - 0.01 15.6 1.4 0.051 13.4 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) MIF4G PF02854.14 EAK90129.1 - 2.6e-30 105.4 8.3 2.6e-30 105.4 5.8 2.2 2 0 0 2 2 2 1 MIF4G domain PAM2 PF07145.10 EAK90129.1 - 4.8e-08 31.9 0.0 4.6e-05 22.6 0.0 2.7 2 0 0 2 2 2 2 Ataxin-2 C-terminal region MA3 PF02847.12 EAK90129.1 - 0.0067 16.1 0.9 0.014 15.0 0.1 2.0 2 0 0 2 2 2 1 MA3 domain POX PF07526.6 EAK90129.1 - 0.49 10.6 0.0 0.49 10.6 0.0 7.4 6 2 0 7 7 7 0 Associated with HOX CS PF04969.11 EAK90130.1 - 8.8e-13 48.6 0.2 1.7e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 CS domain MMR_HSR1_C PF08438.5 EAK90131.1 - 2.1e-24 85.8 0.3 3.8e-24 84.9 0.2 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EAK90131.1 - 3.3e-16 59.2 0.0 1.2e-15 57.5 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAK90131.1 - 1.1e-09 37.7 0.1 8.2e-07 28.4 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B ATP_bind_1 PF03029.12 EAK90131.1 - 0.00016 21.2 0.4 0.052 13.0 0.1 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein G-alpha PF00503.15 EAK90131.1 - 0.0068 15.1 6.2 0.0091 14.7 0.6 3.0 2 1 0 3 3 3 1 G-protein alpha subunit GTP_EFTU PF00009.22 EAK90131.1 - 0.01 15.3 0.1 0.28 10.5 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ArgK PF03308.11 EAK90131.1 - 0.062 12.0 0.0 0.14 10.9 0.0 1.5 1 0 0 1 1 1 0 ArgK protein SRP19 PF01922.12 EAK90132.1 - 1.8e-23 82.9 0.0 3.4e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein Ribonuc_red_lgC PF02867.10 EAK90133.1 - 3.2e-215 715.7 0.0 3.9e-215 715.4 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EAK90133.1 - 3.3e-22 78.0 0.0 6.8e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EAK90133.1 - 9.9e-12 45.1 0.0 3.4e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 EAK90133.1 - 0.0014 16.8 0.0 0.002 16.2 0.0 1.2 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Adaptin_N PF01602.15 EAK90134.1 - 4.2e-20 71.5 15.7 8e-13 47.5 0.1 5.2 4 1 0 5 5 5 5 Adaptin N terminal region cEGF PF12662.2 EAK90135.1 - 2.3e-16 59.0 142.9 0.56 9.9 0.2 30.5 30 1 0 30 30 30 24 Complement Clr-like EGF-like GTP_EFTU PF00009.22 EAK90136.1 - 2.4e-32 111.9 0.0 1.4e-31 109.3 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EAK90136.1 - 6.9e-17 61.3 3.7 6.9e-17 61.3 0.2 2.4 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EAK90136.1 - 8.3e-15 54.6 1.8 5.2e-09 36.0 0.1 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EAK90136.1 - 3.2e-08 33.1 0.0 8.2e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EAK90136.1 - 2e-05 24.4 0.0 0.00013 21.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EAK90136.1 - 0.0068 15.9 0.0 0.031 13.8 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Miro PF08477.8 EAK90136.1 - 0.02 15.4 0.0 0.18 12.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein DUF4225 PF13988.1 EAK90136.1 - 2.5 7.5 5.4 7.4 6.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4225) AAA_16 PF13191.1 EAK90136.1 - 6.7 6.6 11.3 8.2 6.3 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain mRNA_cap_enzyme PF01331.14 EAK90137.1 - 6.6e-38 130.3 0.1 3.8e-26 91.9 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EAK90137.1 - 4.7e-09 36.5 0.7 4.1e-08 33.4 0.5 2.3 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EAK90137.1 - 0.0046 16.3 0.1 0.013 14.9 0.1 1.9 1 1 0 1 1 1 1 ATP dependent DNA ligase domain CutA1 PF03091.10 EAK90138.1 - 5.7e-33 112.6 1.6 6.7e-33 112.3 1.1 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein SID-1_RNA_chan PF13965.1 EAK90138.1 - 0.035 12.2 0.2 0.037 12.2 0.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NOT2_3_5 PF04153.13 EAK90139.1 - 4.5e-25 88.0 1.4 4.5e-25 88.0 1.0 2.6 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family LUC7 PF03194.10 EAK90140.1 - 7.9e-58 195.9 8.0 1.3e-57 195.2 5.6 1.3 1 0 0 1 1 1 1 LUC7 N_terminus Nnf1 PF03980.9 EAK90140.1 - 0.0015 18.4 0.3 0.0036 17.2 0.2 1.6 1 0 0 1 1 1 1 Nnf1 Thioredoxin_2 PF13098.1 EAK90140.1 - 0.1 12.8 0.8 0.34 11.1 0.1 2.3 2 1 0 2 2 2 0 Thioredoxin-like domain DUF4200 PF13863.1 EAK90140.1 - 0.23 11.4 4.5 0.16 11.8 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Rad10 PF03834.9 EAK90141.1 - 2.9e-27 94.1 0.8 5.1e-27 93.3 0.5 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 PF12826.2 EAK90141.1 - 1.3e-09 37.8 0.0 2.8e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EAK90141.1 - 2.9e-08 33.7 0.0 8.7e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.18 EAK90141.1 - 2.7e-06 26.7 0.2 7e-06 25.4 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.2 EAK90141.1 - 0.011 15.6 0.1 0.093 12.6 0.0 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix motif DUF790 PF05626.6 EAK90141.1 - 0.018 13.5 0.1 0.027 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF790) HHH_8 PF14716.1 EAK90141.1 - 0.14 12.3 0.1 0.38 10.9 0.1 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain Motile_Sperm PF00635.21 EAK90142.1 - 4.4e-23 81.0 0.0 9.7e-23 79.8 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain SOG2 PF10428.4 EAK90142.1 - 0.00071 18.3 0.5 0.002 16.8 0.1 1.7 2 0 0 2 2 2 1 RAM signalling pathway protein Uso1_p115_C PF04871.8 EAK90142.1 - 0.0061 16.4 2.3 0.011 15.6 1.6 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region HALZ PF02183.13 EAK90142.1 - 0.0088 15.7 3.4 0.017 14.7 2.3 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Bacillus_HBL PF05791.6 EAK90142.1 - 0.046 13.1 0.8 0.081 12.2 0.5 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) EMP24_GP25L PF01105.19 EAK90142.1 - 0.083 12.6 1.5 0.11 12.1 0.7 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD AATF-Che1 PF13339.1 EAK90142.1 - 0.34 11.0 3.1 0.34 11.0 1.2 1.6 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Helicase_C_2 PF13307.1 EAK90143.1 - 1.4e-62 210.5 1.7 8e-62 208.0 0.0 2.6 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.10 EAK90143.1 - 2.2e-39 134.6 4.1 2.8e-37 127.7 2.9 2.5 1 1 0 1 1 1 1 DEAD_2 DEAD PF00270.24 EAK90143.1 - 3e-05 23.5 0.4 0.28 10.6 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EAK90143.1 - 0.00022 21.1 9.8 0.00038 20.3 0.0 3.6 4 1 1 5 5 5 2 Type III restriction enzyme, res subunit PhoH PF02562.11 EAK90143.1 - 0.057 12.6 0.2 4.3 6.5 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 EAK90143.1 - 0.14 12.3 3.4 8.2 6.5 0.2 3.1 3 0 0 3 3 3 0 AAA domain RRM_1 PF00076.17 EAK90144.1 - 7.7e-15 54.2 0.0 1.4e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK90144.1 - 7.5e-13 48.2 0.0 1.3e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK90144.1 - 8.9e-10 38.2 0.0 1.5e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S6PP PF05116.8 EAK90145.1 - 1.1e-35 123.1 0.0 1.4e-18 67.0 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 EAK90145.1 - 2.6e-14 53.4 0.1 1.8e-13 50.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAK90145.1 - 0.094 12.8 0.2 2 8.5 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HA PF03457.9 EAK90145.1 - 0.12 12.4 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Helicase associated domain COG7 PF10191.4 EAK90146.1 - 5.9e-08 31.1 15.4 5e-06 24.7 1.0 2.5 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) Turandot PF07240.6 EAK90146.1 - 1.6 8.2 6.0 4.5 6.8 0.2 3.2 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot RNase_H PF00075.19 EAK90146.1 - 3.7 7.8 6.8 2.4 8.5 0.0 3.7 4 1 1 5 5 5 0 RNase H Ribosomal_S19 PF00203.16 EAK90148.1 - 3.8e-28 96.9 0.8 1.2e-27 95.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S19 Herpes_ICP4_N PF03584.10 EAK90149.1 - 0.36 10.3 2.1 0.77 9.2 0.1 2.3 2 0 0 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region Curto_V2 PF07325.6 EAK90149.1 - 0.87 9.2 15.9 0.11 12.1 4.3 3.3 2 1 1 3 3 3 0 Curtovirus V2 protein zf-CCCH PF00642.19 EAK90150.1 - 1.1e-08 34.5 4.1 1.1e-08 34.5 2.8 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 EAK90150.1 - 2.7e-06 26.9 6.7 4.7e-06 26.1 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAK90150.1 - 3.3e-06 26.8 8.9 5.7e-06 26.0 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAK90150.1 - 4.6e-06 26.5 11.1 9.5e-06 25.5 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK90150.1 - 2.6e-05 23.8 11.5 4.8e-05 22.9 8.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EAK90150.1 - 0.0012 18.4 12.3 0.0012 18.4 8.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAK90150.1 - 0.02 14.6 7.2 0.02 14.6 5.0 2.4 3 0 0 3 3 3 0 RING-type zinc-finger zf-P11 PF03854.9 EAK90150.1 - 0.91 9.0 8.1 2.6 7.5 5.6 1.8 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.1 EAK90150.1 - 1.5 8.7 8.5 3.7 7.4 5.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SPX PF03105.14 EAK90151.1 - 1.1e-29 104.1 10.8 1.1e-29 104.1 7.5 4.0 2 2 0 3 3 3 1 SPX domain DUF202 PF02656.10 EAK90151.1 - 5.5e-14 52.1 1.5 1.6e-13 50.6 1.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF4199 PF13858.1 EAK90151.1 - 0.012 15.5 1.1 0.012 15.5 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) eRF1_2 PF03464.10 EAK90152.1 - 6.2e-44 149.5 0.5 1.3e-43 148.4 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.10 EAK90152.1 - 4.5e-40 136.4 0.1 1e-39 135.2 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EAK90152.1 - 5e-25 87.5 0.1 8.1e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 EAK90152.1 - 0.00086 18.7 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRM_1 PF00076.17 EAK90153.1 - 4.7e-11 42.1 0.0 7.8e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK90153.1 - 2.1e-08 34.0 0.0 3.1e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK90153.1 - 8.5e-05 22.3 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3584 PF12128.3 EAK90154.1 - 7.6e-06 23.5 32.1 1.2e-05 22.8 22.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Rop-like PF05082.8 EAK90154.1 - 0.081 12.4 4.0 0.69 9.4 0.5 3.0 2 0 0 2 2 2 0 Rop-like FadA PF09403.5 EAK90154.1 - 0.54 10.2 29.8 0.059 13.3 2.2 4.3 1 1 3 4 4 4 0 Adhesion protein FadA NPV_P10 PF05531.7 EAK90154.1 - 7.6 6.8 24.5 0.078 13.2 0.9 5.4 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein P5CR_dimer PF14748.1 EAK90155.1 - 1.9e-22 79.2 0.0 2.6e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EAK90155.1 - 3e-14 53.2 0.0 1e-13 51.5 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EAK90155.1 - 0.027 14.9 0.0 0.049 14.1 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.18 EAK90155.1 - 0.054 13.2 0.2 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ribosomal_S30 PF04758.9 EAK90156.1 - 5.3e-28 96.5 9.5 5.8e-28 96.4 6.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Alpha-amylase PF00128.19 EAK90157.1 - 3.5e-24 85.7 0.1 5e-11 42.5 0.0 2.8 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EAK90157.1 - 1.7e-05 24.9 0.6 4.7e-05 23.4 0.4 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain MyTH4 PF00784.12 EAK90158.1 - 2.8 7.9 6.5 5.5 6.9 0.1 3.1 2 1 1 3 3 3 0 MyTH4 domain MIP-T3 PF10243.4 EAK90160.1 - 0.00012 20.7 34.2 0.00015 20.3 23.7 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 EAK90160.1 - 0.00093 17.3 26.9 0.0011 17.1 18.6 1.0 1 0 0 1 1 1 1 CDC45-like protein Trypan_PARP PF05887.6 EAK90160.1 - 0.014 15.2 22.3 0.014 15.2 15.4 3.4 2 1 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) SAPS PF04499.10 EAK90160.1 - 0.027 13.1 2.3 0.03 12.9 1.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF874 PF05917.6 EAK90160.1 - 0.038 12.8 6.7 0.048 12.5 4.6 1.0 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Plasmodium_Vir PF05795.6 EAK90160.1 - 0.09 11.9 4.1 0.13 11.4 2.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2201_N PF13203.1 EAK90160.1 - 0.78 8.8 18.4 1.1 8.4 12.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Merozoite_SPAM PF07133.6 EAK90160.1 - 4.6 7.0 33.0 6.6 6.6 22.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DDRGK PF09756.4 EAK90160.1 - 7.9 5.8 35.9 13 5.1 24.9 1.3 1 0 0 1 1 1 0 DDRGK domain DUF1777 PF08648.7 EAK90160.1 - 9 5.9 68.2 0.84 9.3 30.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) UQ_con PF00179.21 EAK90161.1 - 9.4e-40 135.2 0.9 2.5e-34 117.7 0.2 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAK90161.1 - 1e-06 28.5 0.0 1.3e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EAK90161.1 - 0.0028 17.5 0.1 0.0042 16.9 0.1 1.6 1 1 0 1 1 1 1 RWD domain Glyco_transf_11 PF01531.11 EAK90161.1 - 0.037 13.0 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 RabGAP-TBC PF00566.13 EAK90162.1 - 2.2e-51 174.3 7.7 2.2e-51 174.3 5.3 2.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Ribosomal_S7 PF00177.16 EAK90163.1 - 1.2e-40 138.4 0.2 1.6e-40 138.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e ProRS-C_1 PF09180.6 EAK90164.1 - 6.5e-24 83.6 0.9 2e-23 82.0 0.6 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EAK90164.1 - 4.7e-21 75.1 0.6 2.8e-20 72.6 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.10 EAK90164.1 - 5.7e-21 74.6 0.0 1.2e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.15 EAK90164.1 - 3e-20 71.9 1.0 2.7e-19 68.8 0.1 2.9 3 0 0 3 3 3 1 Anticodon binding domain V-ATPase_C PF03223.10 EAK90164.1 - 0.0043 16.0 0.7 0.0043 16.0 0.5 1.7 2 0 0 2 2 2 1 V-ATPase subunit C Pico_P2B PF01552.12 EAK90165.1 - 1.4 9.1 6.8 1.6 8.9 0.0 4.4 4 0 0 4 4 4 0 Picornavirus 2B protein zf-Tim10_DDP PF02953.10 EAK90166.1 - 6.5e-12 44.5 0.5 1e-11 43.9 0.4 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ank_2 PF12796.2 EAK90167.1 - 3.2e-50 168.4 0.1 1.4e-18 67.0 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAK90167.1 - 5e-50 164.9 0.4 3.5e-09 36.0 0.0 7.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 EAK90167.1 - 6.2e-47 157.1 5.6 4e-14 52.6 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAK90167.1 - 1.3e-31 105.4 3.0 5.8e-06 26.0 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat RNA_GG_bind PF10258.4 EAK90167.1 - 3.1e-30 103.6 0.7 7.1e-30 102.5 0.5 1.6 1 0 0 1 1 1 1 PHAX RNA-binding domain Ank_5 PF13857.1 EAK90167.1 - 6.8e-29 99.2 1.0 1.9e-08 34.2 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) DUF3447 PF11929.3 EAK90167.1 - 0.00043 20.0 4.5 0.24 11.2 0.0 4.2 4 1 1 5 5 5 2 Domain of unknown function (DUF3447) RRM_1 PF00076.17 EAK90168.1 - 7.7e-37 124.7 1.1 1.9e-18 65.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK90168.1 - 2.5e-28 97.8 0.1 1.3e-14 53.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK90168.1 - 4.3e-20 71.3 0.8 2.3e-09 36.9 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aurora-A_bind PF09041.5 EAK90168.1 - 0.023 14.4 0.1 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Aurora-A binding Myosin_head PF00063.16 EAK90169.1 - 2.7e-179 597.5 8.6 2.7e-179 597.5 5.9 2.4 2 1 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.22 EAK90169.1 - 3.1e-19 66.7 32.1 0.00032 20.0 0.2 6.8 6 0 0 6 6 6 6 IQ calmodulin-binding motif WD40 PF00400.27 EAK90169.1 - 3.2e-13 48.9 2.8 0.001 18.8 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Zeta_toxin PF06414.7 EAK90169.1 - 0.0071 15.4 0.1 0.28 10.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 EAK90169.1 - 0.011 15.4 1.4 0.44 10.1 0.0 3.2 3 0 0 3 3 3 0 NACHT domain AAA_22 PF13401.1 EAK90169.1 - 0.059 13.5 1.9 0.82 9.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain DUF904 PF06005.7 EAK90169.1 - 0.15 12.3 13.3 0.026 14.8 5.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DBI_PRT PF02277.12 EAK90169.1 - 0.37 9.8 0.1 0.82 8.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyltransferase Spt5-NGN PF03439.8 EAK90170.1 - 9.8e-21 73.3 0.0 2.3e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 EAK90170.1 - 8.4e-10 37.9 13.3 0.31 10.8 0.1 7.2 7 0 0 7 7 7 5 KOW motif Spt5_N PF11942.3 EAK90170.1 - 1.7e-07 31.7 11.4 3.1e-07 30.9 7.9 1.4 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal zf-B_box PF00643.19 EAK90171.1 - 4.2e-07 29.7 29.3 4.4e-05 23.2 5.5 3.0 3 0 0 3 3 3 2 B-box zinc finger DEAD PF00270.24 EAK90172.1 - 1.1e-43 148.7 0.0 3e-43 147.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK90172.1 - 1.7e-22 79.0 0.0 9.5e-22 76.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EAK90172.1 - 0.034 14.3 0.4 0.64 10.1 0.1 2.9 3 0 0 3 3 3 0 AAA domain Prp19 PF08606.6 EAK90173.1 - 9e-31 105.4 0.6 1.8e-30 104.4 0.4 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 EAK90173.1 - 7e-06 25.9 0.1 0.00016 21.5 0.0 2.6 2 0 0 2 2 2 1 U-box domain WD40 PF00400.27 EAK90173.1 - 3.9e-05 23.3 3.0 0.00011 21.9 0.1 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-Nse PF11789.3 EAK90173.1 - 0.00035 20.0 0.3 0.00088 18.7 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DEAD PF00270.24 EAK90174.1 - 1.5e-43 148.2 0.0 3.5e-43 147.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK90174.1 - 1.3e-22 79.4 0.1 3.2e-22 78.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.7 EAK90174.1 - 2.3e-08 33.9 0.0 8.3e-08 32.1 0.0 1.9 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.10 EAK90174.1 - 4.2e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WD40 PF00400.27 EAK90175.1 - 1.4e-11 43.7 0.7 0.00012 21.8 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat IL5 PF02025.10 EAK90175.1 - 0.089 12.8 0.0 15 5.6 0.0 2.4 2 0 0 2 2 2 0 Interleukin 5 Cpn60_TCP1 PF00118.19 EAK90176.1 - 1.5e-136 455.8 6.1 1.8e-136 455.6 4.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dak2 PF02734.12 EAK90176.1 - 0.025 14.2 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 DAK2 domain zf-HC5HC2H_2 PF13832.1 EAK90177.1 - 8.5e-11 41.8 8.0 8.5e-11 41.8 5.5 3.1 2 1 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EAK90177.1 - 1e-10 41.5 9.5 1e-10 41.5 6.6 3.1 2 1 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EAK90177.1 - 2.2e-07 30.0 2.4 2.2e-07 30.0 1.6 3.0 4 0 0 4 4 4 1 PHD-finger PHD PF00628.24 EAK90177.1 - 4.9e-05 22.9 6.1 4.9e-05 22.9 4.2 3.6 3 0 0 3 3 3 1 PHD-finger Herpes_HEPA PF03324.9 EAK90177.1 - 0.074 13.0 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 Herpesvirus DNA helicase/primase complex associated protein zf-UDP PF14569.1 EAK90177.1 - 1.2 8.9 9.0 14 5.5 0.1 2.6 2 1 0 2 2 2 0 Zinc-binding RING-finger ABC2_membrane PF01061.19 EAK90178.1 - 4.6e-29 101.1 28.3 4.6e-29 101.1 19.6 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EAK90178.1 - 1.9e-23 83.2 0.0 2.9e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAK90178.1 - 5.4e-09 36.4 9.3 8.3e-06 25.9 0.1 2.8 2 1 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 EAK90178.1 - 5.5e-06 25.6 30.7 5.5e-06 25.6 21.3 2.1 1 1 2 3 3 3 1 ABC-2 family transporter protein AAA_15 PF13175.1 EAK90178.1 - 9.9e-05 21.5 0.4 0.13 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EAK90178.1 - 0.00016 20.9 0.0 0.25 10.5 0.1 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EAK90178.1 - 0.00062 18.9 0.2 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAK90178.1 - 0.0038 17.2 0.0 0.006 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 EAK90178.1 - 0.0076 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EAK90178.1 - 0.014 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EAK90178.1 - 0.015 14.8 0.3 0.04 13.4 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EAK90178.1 - 0.031 13.7 1.4 0.058 12.8 1.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 EAK90178.1 - 0.032 15.0 0.0 0.069 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EAK90178.1 - 0.041 13.2 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EAK90178.1 - 0.043 13.3 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAK90178.1 - 0.052 13.8 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EAK90178.1 - 0.053 13.6 0.2 0.13 12.4 0.1 1.7 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 EAK90178.1 - 0.1 12.1 0.1 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAK90178.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EAK90178.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EAK90178.1 - 0.29 10.0 0.3 0.54 9.1 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TSP_1 PF00090.14 EAK90179.1 - 3.4e-16 59.0 31.4 2.4e-07 30.7 4.0 3.5 3 0 0 3 3 3 3 Thrombospondin type 1 domain EGF PF00008.22 EAK90179.1 - 1e-05 25.3 8.9 7.3e-05 22.6 6.2 2.7 1 0 0 1 1 1 1 EGF-like domain TSP_1 PF00090.14 EAK90180.1 - 9.3e-26 89.7 41.3 3.4e-10 39.8 6.7 4.0 3 1 1 4 4 4 3 Thrombospondin type 1 domain EGF PF00008.22 EAK90180.1 - 4.8e-06 26.4 7.2 4.8e-06 26.4 5.0 2.8 2 0 0 2 2 2 1 EGF-like domain tRNA-synt_1e PF01406.14 EAK90181.1 - 3.3e-124 413.9 0.0 5.1e-124 413.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EAK90181.1 - 3.6e-08 32.4 1.9 0.0042 15.7 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EAK90181.1 - 0.00015 19.9 0.0 0.0017 16.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 EAK90181.1 - 0.0094 14.6 0.1 1.4 7.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) Cmc1 PF08583.5 EAK90181.1 - 0.01 15.5 1.1 0.089 12.5 0.2 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like T2SG PF08334.6 EAK90181.1 - 0.11 12.3 0.1 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G Methyltrans_RNA PF04452.9 EAK90182.1 - 6.7e-44 149.6 0.1 9.7e-38 129.5 0.0 2.1 1 1 0 2 2 2 2 RNA methyltransferase Ebp2 PF05890.7 EAK90183.1 - 2.1e-37 128.8 25.7 2.4e-37 128.7 17.8 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 KOW PF00467.24 EAK90184.1 - 3e-05 23.5 2.9 5.9e-05 22.6 2.0 1.6 1 0 0 1 1 1 1 KOW motif Methyltrans_RNA PF04452.9 EAK90184.1 - 0.0018 17.4 0.2 0.0022 17.1 0.2 1.2 1 0 0 1 1 1 1 RNA methyltransferase TP2 PF01254.13 EAK90184.1 - 1.3 9.4 6.9 0.065 13.5 1.2 1.5 2 0 0 2 2 2 0 Nuclear transition protein 2 Tubulin PF00091.20 EAK90185.1 - 6.4e-72 241.8 0.0 1e-71 241.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EAK90185.1 - 1.3e-47 160.9 0.1 2e-47 160.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EAK90185.1 - 5e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EAK90185.1 - 0.034 13.6 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Pkinase PF00069.20 EAK90188.1 - 5.8e-43 146.9 0.1 4.7e-42 143.9 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK90188.1 - 7.4e-22 77.6 0.0 1.2e-19 70.4 0.0 3.4 2 1 0 2 2 2 1 Protein tyrosine kinase UPF0118 PF01594.11 EAK90188.1 - 3.4 6.5 7.0 0.64 8.9 1.8 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF20 HCaRG PF07258.9 EAK90189.1 - 0.042 13.4 0.0 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 HCaRG protein CRAL_TRIO PF00650.15 EAK90190.1 - 1.3e-07 31.2 0.1 3.6e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO domain HTH_Tnp_Tc3_1 PF11427.3 EAK90190.1 - 0.073 12.7 0.1 0.98 9.1 0.0 2.6 2 0 0 2 2 2 0 Tc3 transposase Borrelia_REV PF03978.8 EAK90192.1 - 0.024 14.3 0.2 0.03 14.0 0.1 1.4 1 1 0 1 1 1 0 Borrelia burgdorferi REV protein IncA PF04156.9 EAK90192.1 - 0.16 11.5 7.5 0.03 13.9 1.4 1.9 2 0 0 2 2 2 0 IncA protein Asp-B-Hydro_N PF05279.6 EAK90192.1 - 2.6 7.8 14.6 4.2 7.1 10.1 1.4 1 1 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SbmA_BacA PF05992.7 EAK90193.1 - 8.7e-40 136.8 6.5 1e-39 136.5 4.5 1.0 1 0 0 1 1 1 1 SbmA/BacA-like family MIF4G PF02854.14 EAK90193.1 - 0.02 14.2 1.8 0.56 9.5 0.3 2.3 2 0 0 2 2 2 0 MIF4G domain EpoR_lig-bind PF09067.5 EAK90193.1 - 0.087 12.8 0.4 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding SbmA_BacA PF05992.7 EAK90194.1 - 1.2e-50 172.5 14.7 1.4e-50 172.2 10.2 1.0 1 0 0 1 1 1 1 SbmA/BacA-like family ABC_membrane_2 PF06472.10 EAK90194.1 - 3.1e-05 23.2 8.8 3.1e-05 23.2 6.1 2.3 2 1 0 2 2 2 1 ABC transporter transmembrane region 2 DUF3523 PF12037.3 EAK90195.1 - 1.3e-109 365.5 21.7 1.7e-109 365.0 15.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.24 EAK90195.1 - 1e-23 84.0 0.0 2.1e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAK90195.1 - 0.0012 17.9 0.9 0.0035 16.4 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EAK90195.1 - 0.0021 18.2 4.5 0.031 14.3 0.1 3.0 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EAK90195.1 - 0.0052 16.6 2.4 0.0069 16.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EAK90195.1 - 0.0067 15.6 0.0 0.022 13.9 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EAK90195.1 - 0.0085 16.9 0.1 0.0085 16.9 0.1 2.6 2 2 0 2 2 2 1 AAA domain NACHT PF05729.7 EAK90195.1 - 0.015 14.9 0.1 0.047 13.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 EAK90195.1 - 0.019 14.3 0.1 1.2 8.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 EAK90195.1 - 0.025 14.5 0.4 0.29 11.0 0.0 2.7 2 1 0 3 3 3 0 AAA ATPase domain AAA_5 PF07728.9 EAK90195.1 - 0.037 13.7 0.0 0.037 13.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) BRAP2 PF07576.7 EAK90196.1 - 0.044 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 BRCA1-associated protein 2 DUF4013 PF13197.1 EAK90197.1 - 0.01 15.1 1.4 0.011 15.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF606 PF04657.8 EAK90197.1 - 0.033 14.2 0.2 0.042 13.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF606 PhoD PF09423.5 EAK90199.1 - 1.3e-17 63.5 0.0 6.9e-15 54.5 0.0 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase TPR_11 PF13414.1 EAK90200.1 - 1.1e-20 73.0 14.3 2.1e-06 27.2 0.7 5.8 4 1 2 6 6 6 4 TPR repeat TPR_1 PF00515.23 EAK90200.1 - 1.1e-15 56.4 2.3 0.0095 15.5 0.1 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EAK90200.1 - 3.6e-11 42.0 18.7 0.14 12.1 0.1 7.8 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 EAK90200.1 - 1.1e-10 40.8 11.1 0.00036 20.5 0.1 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAK90200.1 - 3.8e-10 39.9 2.0 0.039 14.2 0.0 5.9 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAK90200.1 - 2.9e-09 37.3 1.8 0.0015 19.1 0.0 5.7 4 1 1 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EAK90200.1 - 2.7e-07 30.6 15.2 0.31 11.1 0.5 6.2 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EAK90200.1 - 1.1e-06 28.4 17.0 0.0024 17.7 1.0 5.8 2 1 6 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EAK90200.1 - 2e-06 27.9 4.3 0.41 11.4 0.0 6.9 5 1 3 8 8 7 1 Tetratricopeptide repeat APC8 PF04049.8 EAK90200.1 - 2.5e-06 27.2 0.1 6.8e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_9 PF13371.1 EAK90200.1 - 4.2e-06 26.5 0.1 0.39 10.6 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAK90200.1 - 7.6e-06 25.3 5.4 0.17 11.7 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAK90200.1 - 0.00022 20.7 16.4 3.4 7.6 0.2 7.7 5 2 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 EAK90200.1 - 0.0019 18.5 8.0 7.8 7.1 0.0 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAK90200.1 - 0.036 13.9 3.2 22 5.0 0.0 5.5 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TFIIB PF00382.14 EAK90201.1 - 0.068 12.9 0.0 5.3 6.9 0.0 3.0 4 0 0 4 4 4 0 Transcription factor TFIIB repeat HTH_36 PF13730.1 EAK90201.1 - 0.087 12.9 1.0 3.1 7.9 0.2 3.1 2 0 0 2 2 2 0 Helix-turn-helix domain CBS PF00571.23 EAK90202.1 - 0.046 13.5 0.0 7.5 6.4 0.0 3.2 3 0 0 3 3 3 0 CBS domain tRNA-synt_1b PF00579.20 EAK90203.1 - 9.3e-22 77.4 0.0 1.6e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) His_Phos_2 PF00328.17 EAK90204.1 - 5.3e-47 160.8 1.1 2.1e-46 158.8 0.8 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EAK90204.1 - 2.1e-05 24.6 0.0 0.00024 21.2 0.0 2.4 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) RimK PF08443.6 EAK90204.1 - 0.00022 20.7 0.0 0.00083 18.8 0.0 2.0 1 0 0 1 1 1 1 RimK-like ATP-grasp domain NOB1_Zn_bind PF08772.6 EAK90206.1 - 1.7e-25 88.5 1.6 1.7e-25 88.5 1.1 1.7 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like Daxx PF03344.10 EAK90206.1 - 0.67 8.3 14.6 0.93 7.8 10.1 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EAK90206.1 - 9.2 4.1 10.2 13 3.7 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Lactamase_B_2 PF12706.2 EAK90208.1 - 1.6e-23 83.2 0.1 3.1e-22 79.0 0.0 2.6 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EAK90208.1 - 4.5e-09 35.6 0.1 2.2e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 EAK90208.1 - 8.6e-09 35.3 0.0 5.7e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RNaseH_C PF09293.5 EAK90208.1 - 0.16 11.9 0.0 0.16 11.9 0.0 2.7 2 1 1 3 3 3 0 T4 RNase H, C terminal TaqI_C PF12950.2 EAK90209.1 - 0.039 13.7 0.7 0.044 13.5 0.5 1.2 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain DUF3978 PF13123.1 EAK90209.1 - 0.043 13.2 1.1 0.077 12.3 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3978) Nic96 PF04097.9 EAK90210.1 - 1.7e-09 36.4 8.4 8.4e-05 20.8 0.0 3.4 3 1 0 3 3 3 3 Nup93/Nic96 KxDL PF10241.4 EAK90210.1 - 0.0095 15.8 2.4 0.09 12.6 0.5 2.7 2 0 0 2 2 2 1 Uncharacterized conserved protein Ribosomal_L10 PF00466.15 EAK90211.1 - 1.4e-17 63.4 0.5 2.2e-17 62.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 ER_lumen_recept PF00810.13 EAK90212.1 - 7.2e-41 140.1 6.2 7.2e-41 140.1 4.3 1.9 2 0 0 2 2 2 1 ER lumen protein retaining receptor DUF4064 PF13273.1 EAK90212.1 - 2.2 8.4 8.4 7.8 6.6 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) Rad51 PF08423.6 EAK90213.1 - 4.3e-130 432.1 0.1 6e-130 431.6 0.1 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EAK90213.1 - 2.2e-11 43.4 0.0 5.3e-11 42.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain RecA PF00154.16 EAK90213.1 - 1.6e-09 37.2 0.1 2.2e-09 36.8 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EAK90213.1 - 2.9e-09 36.9 0.7 8.1e-09 35.5 0.5 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 EAK90213.1 - 0.00029 20.0 1.6 0.00042 19.4 0.1 1.9 2 1 0 2 2 2 1 KaiC AAA PF00004.24 EAK90213.1 - 0.00041 20.5 0.7 0.0027 17.9 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HHH PF00633.18 EAK90213.1 - 0.0038 16.8 0.1 0.0081 15.8 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF128 PF01995.11 EAK90213.1 - 0.0084 15.0 0.2 0.013 14.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF128 RNA_pol_A_CTD PF03118.10 EAK90213.1 - 0.032 13.6 0.3 0.061 12.7 0.2 1.4 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain AAA_22 PF13401.1 EAK90213.1 - 0.041 14.0 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain HHH_3 PF12836.2 EAK90213.1 - 0.048 13.6 0.7 0.22 11.4 0.0 2.4 2 1 1 3 3 3 0 Helix-hairpin-helix motif HHH_6 PF14579.1 EAK90213.1 - 0.05 13.6 0.7 1.4 9.0 0.1 2.8 2 1 1 3 3 3 0 Helix-hairpin-helix motif Band_7 PF01145.20 EAK90213.1 - 0.13 12.1 0.1 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 SPFH domain / Band 7 family Histone PF00125.19 EAK90214.1 - 4.2e-19 68.4 0.3 6e-19 67.9 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAK90214.1 - 0.00035 20.5 0.0 0.00074 19.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EAK90214.1 - 0.0011 19.2 0.0 0.0017 18.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A tRNA-synt_2b PF00587.20 EAK90215.1 - 1.2e-40 138.8 0.5 2.1e-40 138.1 0.3 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EAK90215.1 - 1.5e-18 66.5 0.1 4.1e-18 65.1 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.9 EAK90215.1 - 3.2e-11 42.9 0.3 1e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EAK90215.1 - 2.3e-09 36.9 0.0 2.3e-08 33.7 0.0 2.5 2 1 0 2 2 2 1 TGS domain FF PF01846.14 EAK90215.1 - 0.3 11.0 2.2 0.52 10.3 0.1 2.3 2 0 0 2 2 2 0 FF domain LCCL PF03815.14 EAK90216.1 - 1.4e-22 79.5 0.4 1.4e-22 79.5 0.3 3.1 3 0 0 3 3 3 1 LCCL domain PHD PF00628.24 EAK90217.1 - 1.8e-05 24.3 6.8 5.1e-05 22.8 4.7 1.8 1 0 0 1 1 1 1 PHD-finger ubiquitin PF00240.18 EAK90218.1 - 0.0012 18.1 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family ARID PF01388.16 EAK90219.1 - 3.2e-12 46.1 0.6 8.9e-11 41.4 0.0 3.1 3 1 0 3 3 3 1 ARID/BRIGHT DNA binding domain Xpo1 PF08389.7 EAK90220.1 - 6.5e-30 104.0 2.9 6.5e-30 104.0 2.0 4.1 6 0 0 6 6 6 1 Exportin 1-like protein Glyco_trans_1_4 PF13692.1 EAK90222.1 - 1.4e-16 60.8 0.0 3.1e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EAK90222.1 - 4.3e-06 26.2 0.0 1.5e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EAK90222.1 - 0.058 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 TRAPP PF04051.11 EAK90223.1 - 2.5e-35 121.2 0.0 3.1e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component UDPGP PF01704.13 EAK90224.1 - 2.4e-18 65.8 0.0 3.8e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pkinase PF00069.20 EAK90225.1 - 4.1e-68 229.3 0.0 6.3e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK90225.1 - 2.4e-28 98.9 0.0 4.1e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EAK90225.1 - 3.8e-21 72.7 6.8 7.8e-07 27.9 0.3 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EAK90225.1 - 1.2e-19 70.2 3.8 3.8e-11 42.9 0.4 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EAK90225.1 - 2.8e-17 62.0 4.9 3.8e-05 23.2 0.3 4.5 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EAK90225.1 - 1.3e-14 52.6 6.3 0.00069 19.3 0.0 4.8 5 0 0 5 5 4 3 EF-hand domain EF-hand_5 PF13202.1 EAK90225.1 - 1.3e-12 46.4 8.0 0.00012 21.2 0.2 3.9 4 0 0 4 4 4 3 EF hand CBM_20 PF00686.14 EAK90225.1 - 4.7e-12 45.3 0.0 1.2e-11 44.0 0.0 1.7 1 1 1 2 2 2 1 Starch binding domain EF-hand_9 PF14658.1 EAK90225.1 - 5.3e-06 26.2 0.1 0.0024 17.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 EAK90225.1 - 0.00013 21.6 0.6 0.0073 16.0 0.1 2.5 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EAK90225.1 - 0.00014 21.8 0.3 0.68 9.9 0.1 3.2 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.9 EAK90225.1 - 0.0017 17.4 0.0 0.0033 16.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EAK90225.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EAK90225.1 - 0.17 11.6 0.0 0.48 10.1 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family EMP24_GP25L PF01105.19 EAK90226.1 - 1.1e-32 113.2 4.4 1.4e-32 112.9 3.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4160 PF13711.1 EAK90226.1 - 0.009 15.8 0.4 0.069 13.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4160) FrhB_FdhB_C PF04432.8 EAK90226.1 - 0.016 14.5 0.0 0.043 13.2 0.0 1.6 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Pro_dh PF01619.13 EAK90226.1 - 0.02 13.8 1.0 0.024 13.6 0.7 1.1 1 0 0 1 1 1 0 Proline dehydrogenase Baculo_LEF-2 PF03041.9 EAK90226.1 - 0.43 10.2 4.3 0.44 10.2 1.0 1.9 1 1 1 2 2 2 0 lef-2 KH_1 PF00013.24 EAK90228.1 - 1.2e-15 56.9 15.6 1.9e-10 40.2 1.1 5.8 6 0 0 6 6 6 3 KH domain KH_3 PF13014.1 EAK90228.1 - 2.5e-08 33.4 1.4 3.2e-06 26.6 0.1 3.9 2 0 0 2 2 2 1 KH domain KH_2 PF07650.12 EAK90228.1 - 0.00012 21.5 2.7 0.0012 18.3 0.1 3.6 3 0 0 3 3 3 1 KH domain KH_4 PF13083.1 EAK90228.1 - 0.25 11.0 2.5 0.27 10.8 0.0 2.5 3 0 0 3 3 3 0 KH domain Pyr_redox_2 PF07992.9 EAK90229.1 - 6.2e-17 62.1 0.0 2.2e-16 60.3 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAK90229.1 - 1.3e-07 31.9 0.2 2e-06 28.0 0.3 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2200 PF09966.4 EAK90229.1 - 0.013 15.3 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) SPT16 PF08644.6 EAK90230.1 - 6.4e-46 155.9 0.3 6.4e-46 155.9 0.2 3.1 2 1 1 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EAK90230.1 - 2.1e-26 92.3 0.1 2.1e-26 92.3 0.1 3.1 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 EAK90230.1 - 2e-23 82.1 0.0 6.2e-23 80.6 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 EAK90230.1 - 1.9e-20 73.3 0.0 3e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 TFIIA PF03153.8 EAK90230.1 - 0.0001 22.3 6.4 0.0001 22.3 4.5 2.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 EAK90230.1 - 2.5 6.0 45.3 2.4 6.0 12.5 2.6 2 0 0 2 2 2 0 CDC45-like protein Tropomyosin PF00261.15 EAK90231.1 - 0.0019 17.3 11.2 0.0019 17.3 7.8 2.1 2 0 0 2 2 2 1 Tropomyosin Cob_adeno_trans PF01923.13 EAK90231.1 - 0.14 11.9 12.0 0.48 10.1 0.3 3.6 1 1 4 5 5 5 0 Cobalamin adenosyltransferase FAD-SLDH PF12318.3 EAK90231.1 - 0.26 10.9 1.8 0.84 9.3 0.5 2.4 2 1 1 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase Fungal_trans_2 PF11951.3 EAK90231.1 - 0.43 9.1 4.1 0.23 10.0 0.0 2.2 1 1 1 2 2 2 0 Fungal specific transcription factor domain Syntaxin-6_N PF09177.6 EAK90231.1 - 0.58 10.5 19.0 0.14 12.6 2.3 4.2 3 2 1 4 4 4 0 Syntaxin 6, N-terminal Med10 PF09748.4 EAK90231.1 - 1.8 8.3 10.4 0.18 11.6 0.3 3.2 2 2 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Tropomyosin_1 PF12718.2 EAK90231.1 - 6.4 6.6 25.3 0.032 14.0 9.0 2.8 2 1 0 3 3 3 0 Tropomyosin like DUF745 PF05335.8 EAK90231.1 - 9.5 5.6 7.8 4.9 6.6 1.3 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF745) Polyketide_cyc PF03364.15 EAK90232.1 - 1.9e-06 27.8 0.0 2.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MIP-T3 PF10243.4 EAK90233.1 - 3.5e-05 22.4 35.8 3.5e-05 22.4 24.8 1.4 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Mem_trans PF03547.13 EAK90233.1 - 0.0015 16.9 0.0 0.0041 15.4 0.0 1.8 1 1 0 1 1 1 1 Membrane transport protein Daxx PF03344.10 EAK90233.1 - 0.04 12.4 34.0 0.061 11.8 23.5 1.2 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 EAK90233.1 - 0.1 10.2 17.2 0.15 9.7 11.9 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LMBR1 PF04791.11 EAK90233.1 - 0.47 8.9 8.2 0.68 8.4 5.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein BTV_NS2 PF04514.7 EAK90233.1 - 1.2 7.9 25.5 1.9 7.3 17.7 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ycf1 PF05758.7 EAK90233.1 - 1.8 6.1 27.9 2.8 5.5 19.4 1.2 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 EAK90233.1 - 2.7 5.7 40.7 4 5.2 28.2 1.2 1 0 0 1 1 1 0 Nop14-like family Borrelia_P83 PF05262.6 EAK90233.1 - 3 5.9 33.9 4.3 5.4 23.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1510 PF07423.6 EAK90233.1 - 3.1 7.1 46.6 0.095 12.0 28.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SAPS PF04499.10 EAK90233.1 - 3.1 6.3 21.3 0.062 11.9 9.2 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Pkinase PF00069.20 EAK90235.1 - 4.3e-12 45.7 0.3 9.7e-12 44.5 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain HEAT PF02985.17 EAK90236.1 - 2.2e-08 33.4 0.0 0.11 12.6 0.0 3.8 3 0 0 3 3 3 3 HEAT repeat IncA PF04156.9 EAK90236.1 - 0.0069 16.0 4.2 0.0069 16.0 2.9 2.2 2 0 0 2 2 2 1 IncA protein HEAT_2 PF13646.1 EAK90236.1 - 0.018 15.3 0.0 1.5 9.1 0.0 2.9 2 1 0 2 2 2 0 HEAT repeats DUF2115 PF09888.4 EAK90236.1 - 0.048 13.7 0.6 0.048 13.7 0.4 2.8 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) Cnd1 PF12717.2 EAK90236.1 - 0.053 13.3 4.9 0.24 11.2 0.2 2.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EAK90236.1 - 0.074 13.4 0.0 19 5.7 0.0 3.0 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF948 PF06103.6 EAK90236.1 - 1.2 9.0 4.9 6.1 6.7 1.5 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Metallophos_2 PF12850.2 EAK90238.1 - 2.2e-20 73.0 0.0 2.6e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EAK90238.1 - 0.00013 21.4 0.1 0.00039 19.8 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase P4Ha_N PF08336.6 EAK90239.1 - 0.01 15.6 2.3 0.073 12.8 0.0 2.7 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4508 PF14969.1 EAK90239.1 - 0.069 13.1 2.4 0.071 13.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) Peptidase_M16_C PF05193.16 EAK90240.1 - 2.1e-25 89.4 0.0 3.9e-24 85.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EAK90240.1 - 4.5e-14 52.4 0.1 9.4e-14 51.4 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) WD40 PF00400.27 EAK90241.1 - 0.00065 19.4 0.8 0.24 11.3 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat AmoA PF05145.7 EAK90241.1 - 0.48 9.4 0.0 0.86 8.5 0.0 1.3 1 0 0 1 1 1 0 Putative ammonia monooxygenase Ribosomal_L2_C PF03947.13 EAK90242.1 - 9.6e-42 141.8 1.9 1.4e-41 141.3 1.3 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EAK90242.1 - 1.1e-14 54.1 0.3 2.9e-14 52.7 0.1 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Sp100 PF03172.8 EAK90246.1 - 0.1 12.6 1.5 0.13 12.2 0.2 1.9 2 0 0 2 2 2 0 Sp100 domain Guanylate_kin PF00625.16 EAK90247.1 - 5.1e-49 166.2 0.2 5.6e-49 166.0 0.2 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_17 PF13207.1 EAK90247.1 - 1.9e-05 25.4 0.0 3.3e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAK90247.1 - 4.4e-05 23.5 0.1 0.00069 19.6 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EAK90247.1 - 7.1e-05 22.0 0.0 0.00011 21.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Rad17 PF03215.10 EAK90247.1 - 0.00011 20.9 0.0 0.00017 20.3 0.0 1.3 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 EAK90247.1 - 0.00012 22.0 0.0 0.00078 19.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAK90247.1 - 0.00039 20.7 0.0 0.0012 19.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAK90247.1 - 0.00092 19.3 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EAK90247.1 - 0.0013 18.8 0.2 0.0044 17.1 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 EAK90247.1 - 0.0023 17.6 0.9 0.014 15.1 0.6 2.0 1 1 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 EAK90247.1 - 0.0045 17.2 0.1 0.007 16.6 0.1 1.7 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 EAK90247.1 - 0.0073 16.2 0.3 0.031 14.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain Miro PF08477.8 EAK90247.1 - 0.0085 16.5 0.1 0.025 15.0 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein MobB PF03205.9 EAK90247.1 - 0.011 15.4 0.1 0.057 13.1 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EAK90247.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EAK90247.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF3970 PF13113.1 EAK90247.1 - 0.016 14.8 0.3 1.7 8.3 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF3970) NTPase_1 PF03266.10 EAK90247.1 - 0.033 13.9 0.2 0.083 12.5 0.1 2.0 1 1 0 1 1 1 0 NTPase DUF1699 PF08004.6 EAK90247.1 - 0.042 13.3 0.4 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) AAA_24 PF13479.1 EAK90247.1 - 0.1 12.1 0.3 0.89 9.0 0.0 2.3 1 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EAK90247.1 - 0.15 11.7 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 EAK90247.1 - 0.39 10.9 6.2 1 9.6 4.3 1.6 1 1 0 1 1 1 0 AAA domain DUF1682 PF07946.9 EAK90251.1 - 2.1e-70 237.1 6.0 2.4e-70 236.9 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ribosomal_S3_C PF00189.15 EAK90252.1 - 1.2e-18 67.0 0.1 3.2e-18 65.7 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EAK90252.1 - 9.4e-10 37.9 0.1 1.6e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 KH domain CAML PF14963.1 EAK90253.1 - 4.6 6.5 8.3 7.4 5.8 5.8 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand AAA PF00004.24 EAK90256.1 - 1.9e-10 41.0 0.0 5.7e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EAK90256.1 - 9.6e-09 35.2 0.9 2.1e-08 34.1 0.6 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EAK90256.1 - 2.3e-08 34.2 0.0 1.4e-07 31.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAK90256.1 - 5.2e-08 33.0 0.0 9.7e-07 28.9 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 EAK90256.1 - 0.00088 18.9 0.8 0.0013 18.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAK90256.1 - 0.001 18.7 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 EAK90256.1 - 0.0036 16.2 0.0 0.007 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD-helicase PF00580.16 EAK90256.1 - 0.0067 15.7 1.5 0.086 12.1 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain NTPase_1 PF03266.10 EAK90256.1 - 0.0093 15.6 0.1 0.037 13.7 0.1 2.0 1 1 0 1 1 1 1 NTPase AAA_18 PF13238.1 EAK90256.1 - 0.029 14.6 0.1 0.11 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EAK90256.1 - 0.037 12.9 0.0 0.073 12.0 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 EAK90256.1 - 0.045 14.0 0.1 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 ABC transporter cobW PF02492.14 EAK90256.1 - 0.09 12.2 0.3 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.16 EAK90256.1 - 0.11 11.6 0.1 0.82 8.7 0.0 2.4 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Thioesterase PF00975.15 EAK90257.1 - 2.5e-08 34.4 0.4 0.00059 20.1 0.1 3.5 2 1 0 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.2 EAK90257.1 - 3.3e-07 30.4 0.0 5.1e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAK90257.1 - 3.8e-07 29.9 0.0 5.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAK90257.1 - 0.013 15.1 0.1 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold OTU PF02338.14 EAK90258.1 - 0.0027 18.3 0.0 1.6 9.3 0.0 4.4 3 1 0 3 3 3 1 OTU-like cysteine protease CDC50 PF03381.10 EAK90259.1 - 5.5e-21 74.9 5.1 1.5e-19 70.2 3.6 2.3 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family EB1 PF03271.12 EAK90260.1 - 9.2e-12 44.8 2.9 2.3e-11 43.5 2.0 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EAK90260.1 - 3.3e-07 30.3 0.6 3.3e-07 30.3 0.4 2.2 2 1 1 3 3 3 1 Calponin homology (CH) domain Tyr-DNA_phospho PF06087.7 EAK90261.1 - 4.8e-67 226.5 1.7 1.7e-66 224.6 1.2 1.7 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EAK90261.1 - 7.9e-05 22.4 0.3 0.3 10.8 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain DUF2489 PF10675.4 EAK90262.1 - 0.021 14.5 0.3 0.076 12.6 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2489) Ribosomal_L22e PF01776.12 EAK90263.1 - 1.2e-47 160.5 0.5 1.3e-47 160.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family eIF-5_eIF-2B PF01873.12 EAK90264.1 - 1.2e-36 125.1 0.0 3.2e-36 123.7 0.0 1.7 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 EAK90264.1 - 8.6e-15 54.4 0.4 4.5e-13 48.9 0.0 2.8 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Tho2 PF11262.3 EAK90265.1 - 3.5e-20 72.2 18.3 7.5e-11 41.6 10.7 4.1 2 1 0 2 2 2 2 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EAK90265.1 - 7.1e-08 32.1 0.2 3.5e-07 29.9 0.1 2.2 1 0 0 1 1 1 1 Transcription- and export-related complex subunit MFS_1 PF07690.11 EAK90266.1 - 3.1e-06 26.1 25.0 3.1e-06 26.1 17.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RabGAP-TBC PF00566.13 EAK90267.1 - 8.9e-15 54.7 11.0 1.9e-14 53.6 7.6 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 14-3-3 PF00244.15 EAK90268.1 - 6.2e-11 41.8 4.5 8.2e-11 41.4 3.2 1.2 1 0 0 1 1 1 1 14-3-3 protein Cas_Cmr5 PF09701.5 EAK90268.1 - 0.0088 16.2 0.7 4.1 7.6 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cmr5) MIS13 PF08202.6 EAK90268.1 - 0.015 14.3 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family UME PF08064.8 EAK90268.1 - 0.017 15.0 1.2 2.2 8.2 0.1 2.4 2 0 0 2 2 2 0 UME (NUC010) domain NAS PF03059.11 EAK90268.1 - 0.021 13.9 0.5 0.03 13.4 0.3 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein RanGAP1_C PF07834.6 EAK90268.1 - 0.059 12.8 0.2 0.076 12.4 0.1 1.2 1 0 0 1 1 1 0 RanGAP1 C-terminal domain Rotavirus_VP7 PF05868.6 EAK90268.1 - 0.068 12.3 3.0 0.12 11.4 2.0 1.5 1 1 0 1 1 1 0 Rotavirus major outer capsid protein VP7 DUF3510 PF12022.3 EAK90268.1 - 0.07 13.2 4.2 0.56 10.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) Cyclin PF08613.6 EAK90270.1 - 2.1e-19 70.3 0.3 5.5e-19 69.0 0.2 1.9 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EAK90270.1 - 0.021 14.4 0.1 0.045 13.3 0.1 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain TauE PF01925.14 EAK90271.1 - 0.0024 17.3 15.2 0.0024 17.3 10.6 1.6 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE DUF389 PF04087.9 EAK90271.1 - 0.0058 16.5 6.5 0.31 10.9 0.0 3.2 1 1 1 2 2 2 1 Domain of unknown function (DUF389) DUF4131 PF13567.1 EAK90271.1 - 0.05 13.0 5.0 0.22 10.8 1.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) SDF PF00375.13 EAK90271.1 - 0.13 11.0 19.4 0.11 11.2 7.3 2.6 3 0 0 3 3 3 0 Sodium:dicarboxylate symporter family DUF1129 PF06570.6 EAK90271.1 - 1.3 8.3 8.8 7.7 5.7 0.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1129) FTR1 PF03239.9 EAK90271.1 - 2.7 6.8 11.8 0.1 11.5 0.6 2.9 2 1 0 2 2 2 0 Iron permease FTR1 family DUF2663 PF10864.3 EAK90272.1 - 0.72 10.0 3.4 0.36 11.0 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2663) Big_2 PF02368.13 EAK90273.1 - 0.063 13.1 0.0 5 7.0 0.0 3.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) Ribosomal_L35Ae PF01247.13 EAK90274.1 - 6.1e-39 131.6 0.9 7.4e-39 131.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae CTV_P6 PF06706.6 EAK90275.1 - 2.5 7.6 4.6 4.4 6.8 0.6 2.9 3 0 0 3 3 3 0 Citrus tristeza virus 6-kDa protein FtsJ PF01728.14 EAK90276.1 - 7.9e-23 81.3 0.0 2.7e-20 73.1 0.0 2.8 2 0 0 2 2 2 2 FtsJ-like methyltransferase TPT PF03151.11 EAK90277.1 - 3.2e-08 33.3 28.1 0.00045 19.9 1.5 3.6 4 0 0 4 4 4 3 Triose-phosphate Transporter family EamA PF00892.15 EAK90277.1 - 1.9e-07 31.1 1.3 1.9e-07 31.1 0.9 3.7 4 1 0 4 4 4 1 EamA-like transporter family EmrE PF13536.1 EAK90277.1 - 0.00029 20.9 0.7 0.00029 20.9 0.5 3.7 3 1 0 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EAK90277.1 - 0.0017 17.4 6.1 0.0017 17.4 4.2 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter DUF914 PF06027.7 EAK90277.1 - 0.0043 15.9 12.3 0.0043 15.9 8.5 2.3 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EAK90277.1 - 0.016 14.1 17.9 0.0053 15.7 6.9 2.7 3 1 0 3 3 3 0 UAA transporter family Shisa PF13908.1 EAK90277.1 - 0.063 13.4 0.3 0.27 11.3 0.2 2.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Kelch_1 PF01344.20 EAK90279.1 - 8.7e-30 102.0 6.7 3.8e-07 29.5 0.0 6.7 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.1 EAK90279.1 - 1.9e-28 97.9 5.6 4.4e-08 32.7 0.0 6.7 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EAK90279.1 - 1.5e-22 78.7 12.6 1.9e-06 27.7 0.0 6.8 4 2 2 6 6 6 4 Kelch motif Kelch_3 PF13415.1 EAK90279.1 - 7.1e-21 73.8 0.0 0.017 15.3 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB_2 PF02214.17 EAK90279.1 - 7.5e-16 58.1 0.1 2.7e-15 56.3 0.0 2.0 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.10 EAK90279.1 - 5.5e-12 44.9 6.3 0.062 13.0 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 EAK90279.1 - 0.00086 19.2 8.3 1.1 9.2 0.0 4.9 6 1 0 6 6 6 2 Kelch motif Atg14 PF10186.4 EAK90279.1 - 3.6 6.4 13.3 5.5 5.8 9.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 VIT1 PF01988.14 EAK90279.1 - 6 6.2 6.5 9.4 5.6 4.5 1.3 1 0 0 1 1 1 0 VIT family AAA_5 PF07728.9 EAK90280.1 - 0.002 17.8 0.0 0.0076 15.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EAK90280.1 - 0.0075 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EAK90280.1 - 0.016 15.4 0.7 0.15 12.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EAK90280.1 - 0.025 14.7 0.1 0.81 9.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EAK90280.1 - 0.055 13.4 0.0 0.19 11.6 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.12 EAK90280.1 - 0.057 12.8 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 EAK90280.1 - 0.066 14.0 0.0 0.43 11.4 0.0 2.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EAK90280.1 - 0.079 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.1 EAK90280.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Patatin PF01734.17 EAK90281.1 - 3.4e-06 27.1 0.1 0.00023 21.1 0.1 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase MSG PF02349.10 EAK90281.1 - 0.089 12.7 0.7 0.22 11.5 0.5 1.6 1 0 0 1 1 1 0 Major surface glycoprotein TPR_11 PF13414.1 EAK90282.1 - 3.4e-11 42.6 0.2 5.8e-07 29.0 0.0 3.2 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.1 EAK90282.1 - 8.1e-11 42.1 0.1 6.4e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAK90282.1 - 3.3e-09 36.5 0.0 0.022 15.3 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAK90282.1 - 4e-09 35.7 0.3 0.1 12.5 0.0 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAK90282.1 - 8.7e-09 35.8 0.0 0.0021 18.6 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAK90282.1 - 3.3e-08 33.0 0.0 0.00047 20.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAK90282.1 - 2.1e-05 23.9 1.4 3.5 7.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAK90282.1 - 0.00072 19.1 0.2 2.4 8.1 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAK90282.1 - 0.0012 18.7 0.1 0.54 10.2 0.0 4.0 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAK90282.1 - 0.0013 18.2 0.1 1 9.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Cactin_mid PF10312.4 EAK90282.1 - 0.0063 15.8 0.5 0.014 14.6 0.3 1.6 1 0 0 1 1 1 1 Conserved mid region of cactin S-AdoMet_synt_C PF02773.11 EAK90283.1 - 1.5e-64 215.8 0.2 2.5e-64 215.1 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EAK90283.1 - 3e-46 156.2 0.0 5e-46 155.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EAK90283.1 - 3.6e-41 139.4 1.1 6.1e-41 138.6 0.2 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Rad17 PF03215.10 EAK90284.1 - 8.3e-32 110.5 14.3 2.9e-19 69.1 7.3 2.4 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 EAK90284.1 - 1e-05 26.0 1.6 1e-05 26.0 1.1 4.2 2 1 0 2 2 1 1 AAA domain ABC_tran PF00005.22 EAK90284.1 - 0.00011 22.4 0.0 0.00033 20.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EAK90284.1 - 0.00052 20.1 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain MutS_V PF00488.16 EAK90284.1 - 0.00065 19.1 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain V AAA PF00004.24 EAK90284.1 - 0.00095 19.3 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EAK90284.1 - 0.0011 19.8 0.0 0.0033 18.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EAK90284.1 - 0.0043 16.7 0.1 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 EAK90284.1 - 0.0085 15.9 0.1 0.044 13.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EAK90284.1 - 0.029 13.9 0.1 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain SMC_N PF02463.14 EAK90284.1 - 0.043 13.0 0.5 0.092 11.9 0.4 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 EAK90284.1 - 0.088 12.2 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EAK90284.1 - 0.094 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Adap_comp_sub PF00928.16 EAK90285.1 - 1.3e-83 280.1 1.7 1.6e-83 279.8 1.2 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EAK90285.1 - 6.4e-08 32.4 3.2 1.2e-07 31.5 2.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Rad9 PF04139.8 EAK90286.1 - 0.015 14.4 0.2 0.026 13.6 0.1 1.3 1 0 0 1 1 1 0 Rad9 DUF1507 PF07408.6 EAK90286.1 - 0.045 13.4 1.7 5.1 6.9 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1507) OMPdecase PF00215.19 EAK90286.1 - 0.088 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family DCP2 PF05026.8 EAK90287.1 - 1.6e-25 88.7 2.1 3.6e-25 87.6 1.4 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EAK90287.1 - 1.1e-12 47.7 0.0 2.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain ABC_membrane_2 PF06472.10 EAK90288.1 - 2.8e-42 144.7 9.4 4.8e-42 144.0 6.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EAK90288.1 - 7.4e-18 65.1 0.0 1.7e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.7 EAK90288.1 - 1.3e-08 34.4 2.4 3.8e-08 32.9 1.7 1.8 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_29 PF13555.1 EAK90288.1 - 0.0019 17.7 0.1 0.0044 16.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EAK90288.1 - 0.0037 16.4 0.0 0.0073 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NACHT PF05729.7 EAK90288.1 - 0.0039 16.8 0.0 0.0093 15.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Sigma54_activat PF00158.21 EAK90288.1 - 0.0044 16.5 0.0 0.34 10.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain SMC_N PF02463.14 EAK90288.1 - 0.0049 16.1 0.1 0.025 13.8 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EAK90288.1 - 0.0068 16.7 0.4 0.0068 16.7 0.3 3.3 2 1 2 4 4 4 1 AAA domain Miro PF08477.8 EAK90288.1 - 0.0086 16.5 0.0 0.025 15.0 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EAK90288.1 - 0.016 15.2 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC_membrane PF00664.18 EAK90288.1 - 0.031 13.7 12.8 0.077 12.4 8.9 1.5 1 1 0 1 1 1 0 ABC transporter transmembrane region AAA_5 PF07728.9 EAK90288.1 - 0.042 13.5 0.1 7.3 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EAK90288.1 - 0.077 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MCM PF00493.18 EAK90288.1 - 0.083 11.6 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA_22 PF13401.1 EAK90288.1 - 0.092 12.8 0.1 0.5 10.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EAK90288.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EAK90288.1 - 0.6 10.9 2.3 1.5 9.6 0.5 2.4 2 1 0 2 2 2 0 AAA domain DUF402 PF04167.8 EAK90289.1 - 0.058 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF402) Peptidase_C50 PF03568.12 EAK90291.1 - 8.9e-37 126.6 8.2 8.9e-37 126.6 5.7 4.1 3 1 0 3 3 3 1 Peptidase family C50 NOT2_3_5 PF04153.13 EAK90292.1 - 2e-32 111.8 8.8 3.7e-32 111.0 6.1 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Kin17_mid PF10357.4 EAK90294.1 - 3.4e-41 139.8 7.4 3.4e-41 139.8 5.2 1.7 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EAK90294.1 - 0.0015 18.6 3.7 0.0051 16.9 2.6 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EAK90294.1 - 0.012 15.7 3.6 0.012 15.7 2.5 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Peptidase_C1 PF00112.18 EAK90297.1 - 2.3e-38 132.2 2.3 5e-38 131.1 1.6 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EAK90297.1 - 0.00044 18.9 0.1 0.00044 18.9 0.1 1.9 2 0 0 2 2 2 1 Peptidase C1-like family zf-HC5HC2H PF13771.1 EAK90299.1 - 0.015 15.4 6.7 0.044 13.9 4.6 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EAK90299.1 - 0.046 13.7 4.1 0.11 12.4 2.8 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain ENT PF03735.9 EAK90299.1 - 0.074 12.7 0.6 0.2 11.4 0.4 1.7 1 0 0 1 1 1 0 ENT domain TFIID_20kDa PF03847.8 EAK90300.1 - 2.2e-05 24.6 0.0 5.7e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 EAK90300.1 - 0.0024 17.9 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF643 PF04867.7 EAK90300.1 - 0.015 15.7 0.1 0.028 14.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF643) TFIID-31kDa PF02291.10 EAK90300.1 - 0.036 13.8 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.11 EAK90300.1 - 0.039 13.7 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF4029 PF13221.1 EAK90300.1 - 0.055 13.8 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4029) CENP-S PF15630.1 EAK90300.1 - 0.094 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S MitMem_reg PF13012.1 EAK90301.1 - 2.5e-26 91.9 0.0 4.3e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EAK90301.1 - 2.3e-25 88.5 0.0 3.5e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pox_MCEL PF03291.11 EAK90302.1 - 4.3e-39 134.3 11.8 2.8e-38 131.6 8.2 2.1 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 EAK90302.1 - 1.7e-11 43.9 0.3 3.3e-11 42.9 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAK90302.1 - 5.5e-10 39.6 0.0 1.5e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAK90302.1 - 2.3e-09 37.1 0.0 5.1e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAK90302.1 - 7.2e-09 36.2 0.0 1.8e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAK90302.1 - 8.9e-09 35.6 0.0 2e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAK90302.1 - 1.8e-08 34.7 0.0 4.1e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAK90302.1 - 0.00028 20.9 0.0 0.00049 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain mRNA_triPase PF02940.10 EAK90302.1 - 0.00062 19.5 1.6 0.00092 19.0 0.2 2.0 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain CMAS PF02353.15 EAK90302.1 - 0.0046 16.0 0.3 0.01 14.9 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_20 PF12147.3 EAK90302.1 - 0.026 13.4 0.1 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 EAK90302.1 - 0.055 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MCM PF00493.18 EAK90304.1 - 1.2e-134 448.3 1.1 1.6e-134 447.9 0.8 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EAK90304.1 - 9.5e-29 100.3 0.1 3.1e-28 98.6 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EAK90304.1 - 2e-06 27.1 0.0 3.1e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EAK90304.1 - 0.0072 16.0 0.0 0.027 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EAK90304.1 - 0.067 13.5 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EAK90304.1 - 0.068 12.6 0.0 0.21 11.0 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Clat_adaptor_s PF01217.15 EAK90305.1 - 0.0031 17.2 2.2 0.0056 16.3 1.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Hexapep PF00132.19 EAK90307.1 - 2.5e-07 29.8 19.4 0.00033 20.0 1.5 4.1 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 EAK90307.1 - 0.0026 16.4 4.8 0.007 14.9 0.5 2.1 1 1 1 2 2 2 2 L-fucokinase Hexapep_2 PF14602.1 EAK90307.1 - 0.006 16.1 13.2 2.8 7.5 2.1 3.4 2 1 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase DUF1082 PF06449.6 EAK90308.1 - 0.036 13.9 0.6 0.036 13.9 0.4 2.1 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) Rhomboid PF01694.17 EAK90309.1 - 1.8e-28 99.4 17.4 1.8e-28 99.4 12.1 2.0 3 0 0 3 3 3 1 Rhomboid family Wzy_C PF04932.10 EAK90309.1 - 0.031 14.0 0.1 0.031 14.0 0.0 2.8 4 0 0 4 4 4 0 O-Antigen ligase Maf1 PF09174.5 EAK90311.1 - 7.3e-48 162.7 1.2 8.6e-48 162.5 0.8 1.1 1 0 0 1 1 1 1 Maf1 regulator IPK PF03770.11 EAK90312.1 - 6.3e-14 52.0 1.4 2.9e-13 49.9 0.5 2.2 2 0 0 2 2 2 1 Inositol polyphosphate kinase HEAT_EZ PF13513.1 EAK90313.1 - 4.8e-15 55.5 2.8 4.7e-06 26.9 0.0 7.7 6 2 2 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.1 EAK90313.1 - 3.6e-12 46.3 0.0 0.049 13.9 0.0 6.0 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EAK90313.1 - 2e-09 36.7 13.9 0.004 17.1 0.0 9.0 10 1 0 10 10 10 2 HEAT repeat IBN_N PF03810.14 EAK90313.1 - 1.3e-08 34.5 3.6 2e-08 34.0 0.3 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EAK90313.1 - 1.8e-06 28.2 0.2 0.059 13.7 0.0 3.4 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EAK90313.1 - 0.015 14.6 0.1 4.5 6.5 0.0 3.6 4 0 0 4 4 4 0 CLASP N terminal mRNA_stabil PF13929.1 EAK90313.1 - 0.043 12.7 0.1 0.085 11.8 0.1 1.4 1 0 0 1 1 1 0 mRNA stabilisation QH-AmDH_gamma PF08992.6 EAK90313.1 - 0.068 12.9 0.1 3.3 7.5 0.0 3.0 2 1 1 3 3 3 0 Quinohemoprotein amine dehydrogenase, gamma subunit NBP1 PF08537.5 EAK90313.1 - 0.28 10.3 0.0 0.5 9.5 0.0 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Arm PF00514.18 EAK90313.1 - 0.32 10.9 8.2 9 6.2 0.1 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Spc97_Spc98 PF04130.8 EAK90315.1 - 1.5e-45 155.5 32.4 2.7e-45 154.7 22.5 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family Pkinase PF00069.20 EAK90316.1 - 6.8e-43 146.6 0.4 1.5e-42 145.5 0.3 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK90316.1 - 6.3e-12 45.1 0.0 1.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_polI_A14 PF08203.6 EAK90316.1 - 0.17 12.1 0.1 16 5.8 0.0 2.7 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 IFT57 PF10498.4 EAK90317.1 - 0.016 13.9 0.1 0.021 13.5 0.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Reo_sigmaC PF04582.7 EAK90317.1 - 0.047 12.8 0.1 0.062 12.4 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 EAK90317.1 - 0.054 13.3 0.2 0.083 12.7 0.1 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF4200 PF13863.1 EAK90317.1 - 0.065 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ATG16 PF08614.6 EAK90317.1 - 0.078 12.7 0.2 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) LsmAD PF06741.8 EAK90319.1 - 6e-18 64.7 2.2 2.6e-17 62.6 1.5 2.2 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 EAK90319.1 - 6.1e-06 26.0 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.10 EAK90319.1 - 0.00085 18.6 2.3 0.0019 17.5 1.6 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region COPIIcoated_ERV PF07970.7 EAK90320.1 - 1.1e-59 201.8 1.2 1.4e-59 201.3 0.8 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EAK90320.1 - 9.2e-28 96.0 4.4 6.2e-27 93.4 0.7 2.4 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Stc1 PF12898.2 EAK90320.1 - 0.029 14.4 1.3 0.063 13.3 0.9 1.5 1 0 0 1 1 1 0 Stc1 domain Fzo_mitofusin PF04799.8 EAK90321.1 - 0.012 15.0 0.3 0.03 13.6 0.2 1.6 1 0 0 1 1 1 0 fzo-like conserved region FOP_dimer PF09398.5 EAK90321.1 - 0.023 14.6 0.9 0.051 13.5 0.2 1.9 2 0 0 2 2 2 0 FOP N terminal dimerisation domain DUF2800 PF10926.3 EAK90321.1 - 0.15 11.1 1.1 0.25 10.4 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2800) LMBR1 PF04791.11 EAK90322.1 - 6e-16 58.0 28.5 1.5e-15 56.7 19.7 1.6 1 1 0 1 1 1 1 LMBR1-like membrane protein FA_desaturase PF00487.19 EAK90322.1 - 4.9 6.5 6.8 4.3 6.6 1.1 2.3 2 0 0 2 2 2 0 Fatty acid desaturase Scs3p PF10261.4 EAK90323.1 - 0.012 14.7 11.1 0.019 14.0 5.1 2.7 2 1 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM MMgT PF10270.4 EAK90323.1 - 0.097 13.1 0.3 0.097 13.1 0.2 2.2 2 0 0 2 2 2 0 Membrane magnesium transporter zf-CCCH PF00642.19 EAK90324.1 - 3.2e-06 26.6 9.1 1.7e-05 24.3 0.7 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EAK90324.1 - 0.1 12.1 0.2 0.35 10.3 0.2 1.9 1 0 0 1 1 1 0 Putative zinc-finger domain SLBP_RNA_bind PF15247.1 EAK90326.1 - 3.3e-20 71.6 1.0 1e-19 70.0 0.2 2.1 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain Suppressor_P21 PF11479.3 EAK90327.1 - 0.014 15.1 2.5 0.033 13.9 0.2 2.5 1 1 2 3 3 3 0 RNA silencing suppressor P21 DUF3675 PF12428.3 EAK90327.1 - 0.039 14.2 0.4 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) DUF3270 PF11674.3 EAK90327.1 - 0.062 13.3 0.3 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) HEAT PF02985.17 EAK90328.1 - 3.9e-13 48.2 0.9 0.0018 18.1 0.0 7.9 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 EAK90328.1 - 1.4e-11 44.5 0.0 2e-05 24.7 0.0 5.5 6 0 0 6 6 6 2 HEAT repeats RIX1 PF08167.7 EAK90328.1 - 3.3e-07 30.1 4.8 0.024 14.2 0.2 6.5 5 2 1 6 6 6 2 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.1 EAK90328.1 - 4.7e-06 26.9 0.1 0.28 11.7 0.0 6.4 4 1 3 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EAK90328.1 - 1.8e-05 25.0 1.5 0.31 11.4 0.0 5.9 5 2 2 7 7 7 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EAK90328.1 - 0.0026 17.6 2.8 0.052 13.4 0.3 3.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain UME PF08064.8 EAK90328.1 - 0.015 15.2 7.5 0.3 11.0 0.0 5.3 5 2 2 7 7 7 0 UME (NUC010) domain Arm PF00514.18 EAK90328.1 - 0.017 14.9 0.0 5.4 6.9 0.0 4.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Katanin_con80 PF13925.1 EAK90328.1 - 0.14 11.9 3.2 8.1 6.1 0.0 4.3 4 1 0 4 4 4 0 con80 domain of Katanin SWIB PF02201.13 EAK90329.1 - 3.9e-06 26.4 0.7 3.9e-06 26.4 0.5 2.1 2 0 0 2 2 2 1 SWIB/MDM2 domain DIT1_PvcA PF05141.7 EAK90329.1 - 0.0039 16.5 2.1 0.0076 15.5 0.3 2.1 1 1 1 2 2 2 1 Pyoverdine/dityrosine biosynthesis protein HAUS5 PF14817.1 EAK90329.1 - 0.063 11.8 6.0 0.03 12.8 1.6 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 5 DUF2392 PF10288.4 EAK90329.1 - 0.34 11.2 5.3 8.2 6.8 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2392) TMC PF07810.8 EAK90330.1 - 0.28 11.6 3.7 0.75 10.2 2.5 1.9 1 1 0 1 1 1 0 TMC domain UPF0172 PF03665.8 EAK90331.1 - 1.4e-18 67.0 0.0 1.9e-17 63.4 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 EAK90331.1 - 0.001 18.7 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CLPTM1 PF05602.7 EAK90332.1 - 1.2e-74 251.6 15.0 1.8e-74 251.0 10.4 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 EAK90332.1 - 0.0093 15.4 0.2 0.0093 15.4 0.1 3.3 3 0 0 3 3 3 1 PQ loop repeat ATPase_gene1 PF09527.5 EAK90332.1 - 1.5 8.7 8.6 0.048 13.4 1.4 2.0 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) FHA PF00498.21 EAK90333.1 - 4.4e-18 65.1 0.4 5.8e-11 42.3 0.2 2.8 2 0 0 2 2 2 2 FHA domain zf-C3HC4_4 PF15227.1 EAK90333.1 - 1.5e-09 37.5 9.1 5.4e-09 35.7 6.4 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EAK90333.1 - 2e-08 33.7 9.1 6e-08 32.2 6.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAK90333.1 - 3.7e-08 32.9 5.5 7.3e-08 31.9 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK90333.1 - 5.2e-08 32.7 11.1 1.5e-07 31.3 7.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAK90333.1 - 1.3e-07 31.3 10.6 3.4e-07 29.9 7.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EAK90333.1 - 3.6e-05 23.3 8.3 8.4e-05 22.2 5.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EAK90333.1 - 4.9e-05 22.9 4.3 7.2e-05 22.4 1.3 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EAK90333.1 - 0.22 11.1 9.5 0.046 13.2 2.4 2.8 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain ELMO_CED12 PF04727.8 EAK90334.1 - 1.8e-56 190.3 0.4 3.2e-56 189.5 0.3 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Plasmod_dom_1 PF09715.5 EAK90337.1 - 7.7 6.5 8.8 0.26 11.2 0.3 2.7 3 0 0 3 3 3 0 Plasmodium protein of unknown function (Plasmod_dom_1) Patatin PF01734.17 EAK90338.1 - 1.2e-14 54.6 0.0 2.7e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Fzo_mitofusin PF04799.8 EAK90338.1 - 0.0018 17.7 1.7 0.004 16.5 1.2 1.6 1 0 0 1 1 1 1 fzo-like conserved region DUF948 PF06103.6 EAK90338.1 - 0.057 13.2 2.6 7.6 6.4 0.7 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Serine_rich PF08824.5 EAK90338.1 - 0.059 13.0 1.1 0.37 10.4 0.3 2.2 1 1 1 2 2 2 0 Serine rich protein interaction domain ER_lumen_recept PF00810.13 EAK90339.1 - 7.8e-39 133.5 17.8 7.8e-39 133.5 12.3 2.2 2 1 0 2 2 2 1 ER lumen protein retaining receptor SNF5 PF04855.7 EAK90341.1 - 0.00036 20.0 0.2 0.00071 19.1 0.2 1.6 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Pkinase PF00069.20 EAK90343.1 - 5.7e-52 176.4 0.0 1.1e-51 175.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK90343.1 - 2.6e-47 161.0 0.0 3.6e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAK90343.1 - 0.0066 15.4 0.0 0.014 14.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAK90343.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF685 PF05085.7 EAK90344.1 - 0.033 13.2 0.6 0.035 13.1 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF685) MFS_1 PF07690.11 EAK90345.1 - 3.4e-22 78.6 38.6 2.3e-20 72.5 2.8 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EAK90345.1 - 9.2e-17 60.7 27.1 1.5e-15 56.7 1.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EAK90345.1 - 6.5e-09 34.3 18.3 6.8e-05 21.1 2.1 3.3 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Tir_receptor_C PF07489.6 EAK90345.1 - 2.4 7.8 6.7 0.18 11.5 1.0 1.7 1 1 1 2 2 2 0 Translocated intimin receptor (Tir) C-terminus HypA PF01155.14 EAK90346.1 - 0.018 14.7 1.1 0.093 12.4 0.4 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Bromodomain PF00439.20 EAK90347.1 - 0.0034 17.2 0.1 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain tRNA_int_end_N2 PF12928.2 EAK90347.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term Leo1 PF04004.8 EAK90348.1 - 5.9e-14 52.1 0.0 1.3e-13 51.0 0.0 1.6 1 1 0 1 1 1 1 Leo1-like protein Ribosomal_L1 PF00687.16 EAK90349.1 - 7.1e-53 179.1 6.0 8.8e-53 178.8 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ufd2P_core PF10408.4 EAK90349.1 - 0.0013 17.1 0.1 0.0022 16.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core PP2C PF00481.16 EAK90350.1 - 3.3e-55 187.2 0.2 3.7e-54 183.7 0.2 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EAK90350.1 - 0.00034 20.0 0.0 0.00065 19.1 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C DUF902 PF06001.8 EAK90351.1 - 0.19 11.9 0.1 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) DUF1804 PF08822.6 EAK90353.1 - 0.12 12.0 0.0 0.6 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) Mpp10 PF04006.7 EAK90354.1 - 4.3e-28 98.0 44.9 5.1e-28 97.8 26.8 3.3 1 1 1 2 2 2 1 Mpp10 protein Pro_dh PF01619.13 EAK90354.1 - 0.033 13.1 0.8 0.061 12.2 0.5 1.4 1 0 0 1 1 1 0 Proline dehydrogenase CTD_bind PF04818.8 EAK90355.1 - 1.7e-10 40.9 0.7 5.1e-10 39.4 0.5 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. PRMT5 PF05185.11 EAK90356.1 - 5.9e-132 440.7 8.8 7.2e-132 440.4 6.1 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 EAK90356.1 - 0.00038 20.4 0.0 0.0007 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EAK90356.1 - 0.00065 18.9 0.1 0.0014 17.8 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.7 EAK90356.1 - 0.0047 17.3 0.0 0.015 15.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAK90356.1 - 0.011 15.0 0.1 0.029 13.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain OTCace PF00185.19 EAK90356.1 - 0.04 13.7 0.0 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PP2C PF00481.16 EAK90357.1 - 5.5e-41 140.6 0.0 1.2e-40 139.5 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EAK90357.1 - 0.00018 21.3 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PSII_BNR PF14870.1 EAK90357.1 - 0.12 11.2 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 PP2C_2 PF13672.1 EAK90357.1 - 0.13 11.6 0.0 0.8 9.0 0.0 2.0 1 1 0 1 1 1 0 Protein phosphatase 2C PAP_assoc PF03828.14 EAK90358.1 - 6.6e-07 29.1 0.2 1.6e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EAK90358.1 - 1.6e-06 28.3 0.0 4.7e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 EAK90358.1 - 0.03 11.9 0.1 0.048 11.1 0.1 1.3 1 0 0 1 1 1 0 Nrap protein Carb_kinase PF01256.12 EAK90359.1 - 2.4e-46 158.0 0.0 5e-34 117.6 0.0 2.1 2 0 0 2 2 2 2 Carbohydrate kinase E2F_TDP PF02319.15 EAK90360.1 - 3.2e-11 42.6 0.6 6.7e-11 41.5 0.4 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain IFT20 PF14931.1 EAK90360.1 - 0.01 15.7 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 HSP90 PF00183.13 EAK90361.1 - 3.3e-137 458.0 14.6 4.1e-132 441.2 8.8 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 EAK90361.1 - 1.4e-12 47.4 0.1 1.4e-12 47.4 0.1 2.5 3 1 1 4 4 4 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EAK90361.1 - 8.3e-10 38.3 0.1 1.6e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_11 PF13414.1 EAK90362.1 - 6.1e-31 105.8 10.8 2.9e-10 39.6 0.2 5.3 3 1 2 6 6 6 4 TPR repeat TPR_2 PF07719.12 EAK90362.1 - 2.9e-25 86.1 8.7 0.0014 18.4 0.0 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.23 EAK90362.1 - 1.1e-23 81.7 10.4 1.5e-07 30.7 0.1 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EAK90362.1 - 1.3e-17 62.1 5.4 0.00048 19.7 0.1 7.2 8 0 0 8 8 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EAK90362.1 - 2.3e-16 59.6 16.1 2.1e-07 30.9 0.4 5.9 3 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EAK90362.1 - 4e-14 52.3 13.0 2.7e-05 24.0 0.0 6.1 3 1 6 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.1 EAK90362.1 - 1.3e-13 51.0 0.4 0.0057 16.9 0.0 6.4 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EAK90362.1 - 3.3e-13 49.9 0.0 5.2e-05 23.7 0.0 4.5 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAK90362.1 - 2.1e-09 37.1 0.0 0.22 12.2 0.1 6.3 3 1 3 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAK90362.1 - 3.8e-09 36.0 4.2 0.4 11.0 0.0 6.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAK90362.1 - 1.2e-07 31.0 0.4 0.43 10.5 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EAK90362.1 - 0.00068 19.9 0.2 18 6.0 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EAK90362.1 - 0.00086 19.1 0.0 0.91 9.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EAK90362.1 - 0.014 15.3 1.7 18 5.4 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 EAK90362.1 - 0.016 15.0 6.1 0.027 14.3 0.5 3.6 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.7 EAK90362.1 - 0.027 14.0 0.0 0.1 12.1 0.0 2.0 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_4 PF07721.9 EAK90362.1 - 0.077 13.4 0.0 95 3.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EAK90362.1 - 0.1 11.8 0.0 1.6 8.0 0.0 2.6 2 0 0 2 2 2 0 SHNi-TPR TPR_8 PF13181.1 EAK90363.1 - 0.0004 19.9 0.0 11 6.1 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EAK90363.1 - 0.0012 18.5 19.8 0.048 13.4 0.7 6.6 3 2 4 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_2 PF07719.12 EAK90363.1 - 0.0018 18.0 0.0 3.8 7.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAK90363.1 - 0.0024 18.3 0.0 2.6 8.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat HAT PF02184.11 EAK90363.1 - 0.0074 16.0 23.2 3.6 7.4 0.0 6.4 7 0 0 7 7 7 3 HAT (Half-A-TPR) repeat TPR_1 PF00515.23 EAK90363.1 - 0.038 13.6 0.0 17 5.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAK90363.1 - 0.086 13.5 0.0 27 5.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Baculo_IE-1 PF05290.6 EAK90364.1 - 0.009 15.7 0.7 0.012 15.3 0.5 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) COesterase PF00135.23 EAK90364.1 - 0.023 13.4 1.0 0.025 13.3 0.7 1.0 1 0 0 1 1 1 0 Carboxylesterase family FtsK_SpoIIIE_N PF12538.3 EAK90364.1 - 0.025 14.6 0.3 0.038 14.1 0.2 1.4 1 0 0 1 1 1 0 DNA transporter UPF0122 PF04297.9 EAK90364.1 - 0.21 11.6 5.6 0.084 12.9 1.5 2.0 2 1 1 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like Allexi_40kDa PF05549.6 EAK90364.1 - 0.22 10.8 3.0 0.25 10.6 2.1 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Vip3A_N PF12495.3 EAK90364.1 - 0.44 10.2 6.4 0.14 11.7 1.2 2.0 1 1 1 2 2 2 0 Vegetative insecticide protein 3A N terminal LRR_4 PF12799.2 EAK90365.1 - 1.9e-08 33.7 65.8 0.0014 18.2 0.5 10.3 6 5 4 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAK90365.1 - 2.4e-06 27.2 49.8 0.00082 19.0 0.7 8.5 6 2 2 8 8 8 4 Leucine rich repeat LRR_1 PF00560.28 EAK90365.1 - 7.2e-06 25.3 47.6 11 6.4 0.3 13.5 13 2 1 14 14 14 8 Leucine Rich Repeat LRR_6 PF13516.1 EAK90365.1 - 0.00085 19.1 54.6 0.84 9.9 0.0 13.2 13 1 1 14 14 14 4 Leucine Rich repeat LRR_7 PF13504.1 EAK90365.1 - 0.028 14.5 35.8 17 6.1 0.0 12.6 11 2 2 13 13 13 0 Leucine rich repeat polyprenyl_synt PF00348.12 EAK90366.1 - 1.5e-31 109.2 0.0 2.3e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase IBN_N PF03810.14 EAK90366.1 - 0.38 10.6 6.4 0.42 10.5 1.5 2.7 2 0 0 2 2 2 0 Importin-beta N-terminal domain RNA_pol_Rpb2_6 PF00562.23 EAK90367.1 - 4.8e-126 420.5 0.0 8.3e-126 419.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EAK90367.1 - 5.7e-57 191.9 0.0 8.2e-57 191.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EAK90367.1 - 2.1e-44 151.2 0.0 4.3e-44 150.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EAK90367.1 - 4.8e-29 100.4 0.1 1e-28 99.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EAK90367.1 - 2.8e-22 78.2 0.0 7.3e-22 76.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EAK90367.1 - 3.7e-21 74.8 1.1 8.2e-21 73.7 0.7 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.8 EAK90367.1 - 1.2e-16 60.2 0.0 3.3e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 COG4 PF08318.7 EAK90369.1 - 3.6e-20 71.9 13.9 3.6e-20 71.9 9.6 3.6 2 1 0 2 2 2 1 COG4 transport protein DUF1664 PF07889.7 EAK90369.1 - 3.9 7.2 8.0 4.4 7.1 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) HSBP1 PF06825.7 EAK90370.1 - 1.1e-16 60.1 3.8 1.7e-16 59.4 2.6 1.3 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF1664 PF07889.7 EAK90370.1 - 0.0011 18.7 1.9 0.0014 18.4 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Hormone_1 PF00103.15 EAK90370.1 - 0.0053 16.1 1.9 0.0063 15.8 1.3 1.2 1 0 0 1 1 1 1 Somatotropin hormone family V-SNARE PF05008.10 EAK90370.1 - 0.0092 16.1 2.1 0.025 14.7 1.5 1.8 1 1 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus LOH1CR12 PF10158.4 EAK90370.1 - 0.022 14.5 2.4 0.023 14.4 1.2 1.4 1 1 0 1 1 1 0 Tumour suppressor protein CENP-F_leu_zip PF10473.4 EAK90370.1 - 0.079 12.8 3.2 0.1 12.4 2.2 1.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YlqD PF11068.3 EAK90370.1 - 0.14 12.1 4.6 0.073 13.1 0.6 1.9 1 1 1 2 2 2 0 YlqD protein Baculo_PEP_C PF04513.7 EAK90370.1 - 0.18 11.6 3.6 0.62 9.8 2.3 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HR1 PF02185.11 EAK90370.1 - 0.22 11.2 4.0 6.1 6.6 1.7 2.5 1 1 1 2 2 2 0 Hr1 repeat Fzo_mitofusin PF04799.8 EAK90370.1 - 0.31 10.3 2.4 0.45 9.8 1.5 1.4 1 1 1 2 2 2 0 fzo-like conserved region KLRAQ PF10205.4 EAK90370.1 - 0.33 10.9 2.9 0.5 10.4 1.8 1.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Cauli_AT PF03233.8 EAK90370.1 - 0.34 10.6 3.4 0.4 10.3 2.4 1.1 1 0 0 1 1 1 0 Aphid transmission protein Adeno_PIX PF03955.9 EAK90370.1 - 1.5 9.3 3.5 4.2 7.9 0.2 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Syntaxin PF00804.20 EAK90370.1 - 1.6 8.9 7.8 7 6.8 5.4 1.9 1 1 0 1 1 1 0 Syntaxin Cyclin PF08613.6 EAK90371.1 - 9.3e-30 104.0 0.7 1.9e-29 102.9 0.5 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EAK90371.1 - 8.2e-09 35.1 0.1 1.6e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3971 PF13116.1 EAK90371.1 - 0.053 12.9 0.1 0.09 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function Myosin_head PF00063.16 EAK90372.1 - 9.9e-176 585.7 0.4 1.5e-175 585.1 0.3 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 EAK90372.1 - 0.0027 17.8 0.7 0.012 15.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain DEAD PF00270.24 EAK90372.1 - 0.018 14.5 0.1 2 7.8 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase Zeta_toxin PF06414.7 EAK90372.1 - 0.037 13.1 0.0 0.092 11.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EAK90372.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ERp29 PF07749.7 EAK90373.1 - 1.3 9.7 7.9 7.6 7.2 0.4 3.2 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain MutL PF13941.1 EAK90379.1 - 0.15 10.3 0.0 0.33 9.2 0.0 1.5 1 0 0 1 1 1 0 MutL protein Sec63 PF02889.11 EAK90381.1 - 4.5e-41 141.0 0.2 6.5e-41 140.5 0.1 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EAK90381.1 - 4.1e-22 77.6 0.4 9.2e-22 76.5 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3366 PF11846.3 EAK90381.1 - 0.075 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) AATF-Che1 PF13339.1 EAK90382.1 - 0.18 11.9 2.3 2.2 8.4 0.9 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor MSC PF09402.5 EAK90383.1 - 1.1e-41 142.6 1.2 1.9e-41 141.8 0.8 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain MMtag PF10159.4 EAK90384.1 - 1.5e-15 57.0 2.7 2.4e-15 56.3 0.6 2.0 2 0 0 2 2 2 1 Kinase phosphorylation protein DUF1235 PF06822.7 EAK90384.1 - 0.077 11.9 1.1 0.093 11.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) DNA_pol3_delta PF06144.8 EAK90385.1 - 0.047 13.2 3.2 0.07 12.6 2.2 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit HNOB PF07700.10 EAK90385.1 - 0.11 11.9 1.3 0.43 10.0 0.6 1.9 1 1 1 2 2 2 0 Heme NO binding Zn_ribbon_2 PF12674.2 EAK90385.1 - 0.16 12.3 1.4 0.71 10.2 0.1 2.4 2 1 1 3 3 3 0 Putative zinc ribbon domain FF PF01846.14 EAK90386.1 - 0.0014 18.5 0.9 0.24 11.3 0.0 3.7 3 1 0 3 3 3 2 FF domain PX PF00787.19 EAK90387.1 - 9.2e-14 51.2 0.3 2.1e-13 50.0 0.2 1.6 1 0 0 1 1 1 1 PX domain WD40 PF00400.27 EAK90387.1 - 0.00044 20.0 0.7 0.05 13.5 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat PMC2NT PF08066.7 EAK90388.1 - 0.0057 16.9 0.5 0.0057 16.9 0.3 4.0 3 2 2 5 5 5 1 PMC2NT (NUC016) domain FIIND PF13553.1 EAK90388.1 - 0.016 14.6 0.8 0.028 13.8 0.6 1.4 1 0 0 1 1 1 0 Function to find DDE_Tnp_IS66 PF03050.9 EAK90388.1 - 0.65 9.1 3.9 0.28 10.3 0.4 1.9 1 1 0 2 2 2 0 Transposase IS66 family Plectin PF00681.15 EAK90389.1 - 3.7 7.1 23.6 24 4.5 0.1 10.0 12 0 0 12 12 12 0 Plectin repeat SRP72 PF08492.7 EAK90391.1 - 6e-15 55.3 8.0 6e-15 55.3 5.5 2.3 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 EAK90391.1 - 5.6e-10 39.4 4.9 0.12 12.7 0.0 6.3 4 2 3 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EAK90391.1 - 1.1e-06 28.7 15.4 0.00038 20.5 0.9 5.5 3 3 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EAK90391.1 - 9.9e-06 25.0 7.5 3.9 7.6 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAK90391.1 - 0.0012 19.3 0.0 91 4.1 0.0 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAK90391.1 - 0.008 16.5 2.3 80 4.0 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAK90391.1 - 0.0094 15.5 8.9 1.3 8.7 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EAK90391.1 - 0.019 14.5 6.9 6.1 6.5 0.1 4.8 3 2 1 4 4 4 0 TPR repeat TPR_8 PF13181.1 EAK90391.1 - 0.073 12.8 9.0 2.6 8.0 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAK90391.1 - 0.14 12.9 0.0 2.8e+02 2.3 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 EAK90391.1 - 1.2 9.2 3.5 13 5.9 0.0 4.8 6 0 0 6 6 5 0 PPR repeat CLASP_N PF12348.3 EAK90392.1 - 1.6e-07 30.9 1.6 1.7e-07 30.8 0.1 1.8 2 0 0 2 2 2 1 CLASP N terminal RINGv PF12906.2 EAK90393.1 - 4.5e-11 42.6 2.5 4.5e-11 42.6 1.7 2.6 3 0 0 3 3 3 1 RING-variant domain FHA PF00498.21 EAK90393.1 - 2.1e-06 27.7 0.0 1.5e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 FHA domain BING4CT PF08149.6 EAK90394.1 - 1.5e-35 120.5 0.0 1.5e-32 110.9 0.0 2.8 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.27 EAK90394.1 - 0.004 16.9 6.7 0.082 12.8 0.0 4.9 6 0 0 6 6 6 1 WD domain, G-beta repeat Glycos_transf_2 PF00535.21 EAK90395.1 - 5.9e-07 29.3 0.1 1.1e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 EAK90395.1 - 0.0022 17.1 0.2 0.0039 16.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 WD40 PF00400.27 EAK90396.1 - 1.9e-27 94.0 11.5 1.7e-08 33.9 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EAK90396.1 - 2.7e-06 27.2 0.0 0.00053 19.7 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EAK90396.1 - 0.021 12.6 0.0 1.7 6.3 0.0 2.1 2 0 0 2 2 2 0 IKI3 family PP2C PF00481.16 EAK90397.1 - 1.3e-22 80.4 0.0 2.3e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EAK90397.1 - 1.6e-06 27.6 0.0 4.4e-05 22.9 0.0 2.7 2 1 0 2 2 2 1 Protein phosphatase 2C PC-Esterase PF13839.1 EAK90397.1 - 0.026 14.3 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Glycos_transf_2 PF00535.21 EAK90398.1 - 6.1e-24 84.5 0.0 1.2e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EAK90398.1 - 7.9e-10 38.8 5.3 2.7e-08 33.9 4.0 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 EAK90398.1 - 7.7e-09 34.9 0.0 4.5e-07 29.2 0.0 2.6 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 EAK90398.1 - 1.2e-07 31.8 0.0 4.6e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EAK90398.1 - 1.9e-06 27.2 0.0 6.6e-06 25.4 0.0 1.8 2 1 0 2 2 2 1 Glycosyltransferase like family 2 GlcNAc PF11397.3 EAK90398.1 - 0.002 17.3 0.1 0.0052 15.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) RicinB_lectin_2 PF14200.1 EAK90398.1 - 0.054 13.8 0.4 1.6 9.1 0.3 2.4 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like zf-RING_2 PF13639.1 EAK90399.1 - 6.5e-13 48.2 8.6 1.2e-12 47.4 6.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAK90399.1 - 9.2e-07 28.8 6.0 2e-06 27.7 3.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EAK90399.1 - 1.3e-06 27.9 6.8 3.5e-06 26.5 4.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK90399.1 - 1.2e-05 24.9 6.5 2.8e-05 23.7 4.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAK90399.1 - 1.9e-05 24.6 9.4 3.7e-05 23.6 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAK90399.1 - 0.001 18.6 8.3 0.0022 17.6 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EAK90399.1 - 0.0055 16.5 3.2 0.0055 16.5 2.2 2.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger Transglut_core2 PF13369.1 EAK90399.1 - 0.042 13.3 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily RINGv PF12906.2 EAK90399.1 - 0.055 13.5 7.7 0.12 12.3 5.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EAK90399.1 - 0.21 11.3 3.5 0.23 11.2 0.8 2.2 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 EAK90399.1 - 0.23 11.4 8.8 0.094 12.6 3.6 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain zf-Di19 PF05605.7 EAK90399.1 - 0.23 11.5 2.3 9.8 6.3 0.2 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.3 EAK90399.1 - 0.69 9.4 5.7 1.5 8.3 4.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EAK90399.1 - 1.4 8.5 12.7 0.1 12.1 5.1 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Oxidored_q3 PF00499.15 EAK90399.1 - 4.4 7.0 16.5 5.6 6.7 7.8 2.2 1 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Presenilin PF01080.12 EAK90399.1 - 7.4 5.2 13.7 1.9 7.1 7.1 1.8 2 1 0 2 2 2 0 Presenilin E1-E2_ATPase PF00122.15 EAK90400.1 - 2.3e-66 223.1 3.3 2.3e-66 223.1 2.3 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EAK90400.1 - 4.6e-49 166.4 6.8 4.6e-49 166.4 4.7 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EAK90400.1 - 3.7e-30 105.9 0.0 2.1e-28 100.2 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAK90400.1 - 1.7e-18 66.3 0.0 3.8e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EAK90400.1 - 5.1e-16 57.8 0.0 1.4e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EAK90400.1 - 1.7e-14 54.4 0.2 9.3e-14 52.0 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAK90400.1 - 6.8e-05 22.5 1.8 0.0083 15.7 0.5 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAK90400.1 - 0.04 14.1 0.0 0.29 11.3 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EAK90400.1 - 0.088 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RNA_pol_Rpb4 PF03874.11 EAK90401.1 - 6.9e-19 67.9 0.7 6.9e-19 67.9 0.5 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 DNA_pol3_a_NI PF14480.1 EAK90401.1 - 0.068 12.8 0.8 0.13 11.9 0.6 1.6 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I Cpn60_TCP1 PF00118.19 EAK90402.1 - 2.4e-151 504.6 1.1 2.7e-151 504.4 0.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family His_Phos_1 PF00300.17 EAK90403.1 - 3.3e-45 154.0 0.0 4.1e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NIF PF03031.13 EAK90405.1 - 1.9e-23 82.8 0.1 3.4e-23 82.0 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.21 EAK90405.1 - 2.9e-07 30.5 0.1 1.3e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EAK90405.1 - 4.1e-06 26.5 0.1 1.6e-05 24.6 0.1 2.1 1 1 0 1 1 1 1 twin BRCT domain CAP_N PF01213.14 EAK90406.1 - 0.02 14.2 2.2 0.034 13.4 1.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EAK90406.1 - 0.081 12.2 1.5 0.15 11.3 1.1 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CutA1 PF03091.10 EAK90407.1 - 0.19 11.4 0.0 24 4.6 0.0 2.4 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein Avl9 PF09794.4 EAK90408.1 - 0.0026 16.3 0.9 0.0035 15.8 0.6 1.1 1 0 0 1 1 1 1 Transport protein Avl9 Tup_N PF08581.5 EAK90408.1 - 0.0043 17.2 1.8 1 9.5 0.0 2.3 2 0 0 2 2 2 2 Tup N-terminal EzrA PF06160.7 EAK90408.1 - 0.0062 14.7 2.8 0.012 13.8 2.0 1.5 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA KIP1 PF07765.7 EAK90408.1 - 0.03 14.1 0.5 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 KIP1-like protein DUF1719 PF08224.6 EAK90408.1 - 0.045 12.8 0.6 0.07 12.2 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1719) SPX PF03105.14 EAK90408.1 - 0.06 13.1 2.9 0.072 12.8 2.0 1.1 1 0 0 1 1 1 0 SPX domain NPV_P10 PF05531.7 EAK90408.1 - 0.066 13.4 0.6 6.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Filo_VP35 PF02097.10 EAK90408.1 - 0.078 12.1 0.6 0.091 11.9 0.4 1.3 1 1 0 1 1 1 0 Filoviridae VP35 DUF148 PF02520.12 EAK90408.1 - 0.091 12.5 4.2 0.19 11.5 0.3 2.3 1 1 0 2 2 2 0 Domain of unknown function DUF148 Tox-MPTase5 PF15641.1 EAK90408.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 5 Glutaredoxin2_C PF04399.8 EAK90408.1 - 0.13 11.8 1.5 0.26 10.8 0.1 2.2 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain KMP11 PF03037.11 EAK90408.1 - 0.24 12.0 2.4 1.8 9.2 0.3 2.2 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 DUF4263 PF14082.1 EAK90408.1 - 0.29 11.0 4.2 0.81 9.6 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4263) ORF6C PF10552.4 EAK90408.1 - 0.36 10.5 5.7 0.46 10.2 1.1 2.5 2 1 1 3 3 3 0 ORF6C domain RICH PF05062.7 EAK90408.1 - 0.93 9.6 5.7 0.19 11.8 0.8 2.0 1 1 1 2 2 2 0 RICH domain TMF_TATA_bd PF12325.3 EAK90408.1 - 1.1 9.0 4.4 7 6.4 0.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1227 PF06777.6 EAK90409.1 - 2.2e-49 166.8 0.3 4.2e-48 162.7 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 EAK90409.1 - 3.9e-44 150.5 0.4 5.2e-43 146.8 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EAK90409.1 - 2.2e-33 115.1 10.9 5.4e-23 81.2 1.9 5.0 4 1 0 4 4 4 2 DEAD_2 ResIII PF04851.10 EAK90409.1 - 8.3e-10 38.7 0.2 2e-07 31.0 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EAK90409.1 - 0.0011 18.5 0.1 0.13 11.7 0.1 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EAK90409.1 - 0.0019 17.0 0.0 0.02 13.6 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain PhoH PF02562.11 EAK90409.1 - 0.026 13.7 0.2 0.44 9.7 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein AAA_11 PF13086.1 EAK90409.1 - 0.046 13.2 1.0 0.073 12.6 0.2 1.7 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 EAK90410.1 - 2.5e-21 75.7 36.0 2.5e-21 75.7 25.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EAK90410.1 - 0.00041 20.0 8.6 0.0091 15.7 0.2 3.8 2 1 0 2 2 2 2 MFS_1 like family CAP PF00188.21 EAK90411.1 - 1.2e-65 219.6 14.6 3e-22 79.4 0.1 5.3 5 0 0 5 5 5 4 Cysteine-rich secretory protein family DUF1192 PF06698.6 EAK90412.1 - 0.069 12.9 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF2417 PF10329.4 EAK90412.1 - 0.35 10.2 5.9 1.2 8.5 1.8 2.4 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Myosin_head PF00063.16 EAK90414.1 - 2.5e-173 577.7 9.9 2.5e-173 577.7 6.9 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) RCC1 PF00415.13 EAK90414.1 - 2.1e-32 111.0 4.8 1.9e-10 40.7 0.1 6.7 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EAK90414.1 - 3.5e-27 93.3 19.2 3e-10 39.4 0.5 5.7 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.22 EAK90414.1 - 2.5e-07 29.7 36.8 0.0047 16.4 0.3 7.5 7 0 0 7 7 7 4 IQ calmodulin-binding motif AAA_22 PF13401.1 EAK90414.1 - 0.043 13.9 0.1 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EAK90414.1 - 0.071 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.15 EAK90414.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase CbiA PF01656.18 EAK90414.1 - 0.13 11.6 0.2 0.31 10.4 0.1 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1115 PF06544.7 EAK90416.1 - 2.5e-23 82.1 0.0 5e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Zona_pellucida PF00100.18 EAK90416.1 - 0.07 12.5 0.0 1 8.7 0.0 2.0 1 1 1 2 2 2 0 Zona pellucida-like domain DUF1900 PF08954.6 EAK90417.1 - 6.6e-43 145.4 0.0 1.4e-42 144.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 EAK90417.1 - 3.6e-28 96.3 1.5 4.3e-11 42.2 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF1899 PF08953.6 EAK90417.1 - 2.9e-09 36.4 0.1 5.6e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) PSII_BNR PF14870.1 EAK90417.1 - 0.038 13.0 0.1 0.053 12.5 0.1 1.2 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Nup160 PF11715.3 EAK90417.1 - 0.058 11.5 0.1 1.1 7.3 0.0 2.0 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Metallophos PF00149.23 EAK90418.1 - 3.3e-17 62.5 1.2 6.3e-17 61.6 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAK90418.1 - 1.7e-05 24.7 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glycos_transf_2 PF00535.21 EAK90420.1 - 3e-09 36.7 0.0 6.6e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EAK90420.1 - 2.3e-07 30.8 0.0 4.3e-07 29.9 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EAK90420.1 - 0.0083 15.2 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EAK90420.1 - 0.082 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 EF1G PF00647.14 EAK90421.1 - 1.9e-40 136.9 0.2 3.7e-40 135.9 0.2 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EAK90421.1 - 1.3e-07 31.4 0.0 2.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAK90421.1 - 0.0016 18.8 0.0 0.0037 17.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L6e PF01159.14 EAK90422.1 - 2.3e-36 124.2 0.9 3.1e-36 123.8 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e Phage_attach PF05354.6 EAK90422.1 - 0.017 14.6 0.1 0.037 13.5 0.0 1.6 1 1 1 2 2 2 0 Phage Head-Tail Attachment TAA-Trp-ring PF15401.1 EAK90422.1 - 0.42 10.8 2.3 0.69 10.1 1.6 1.3 1 0 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin DSPn PF14671.1 EAK90423.1 - 1.6e-47 161.0 1.1 2.8e-47 160.2 0.3 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EAK90423.1 - 2.7e-10 39.9 0.7 1e-08 34.8 0.0 2.8 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAK90423.1 - 0.00036 19.9 0.1 0.00099 18.5 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EAK90423.1 - 0.0007 19.6 0.1 0.0027 17.7 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EAK90423.1 - 0.012 15.8 0.2 0.032 14.4 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family RRM_1 PF00076.17 EAK90424.1 - 1.7e-33 114.0 2.2 5e-18 64.4 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK90424.1 - 7.4e-28 96.3 0.7 3.8e-13 49.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK90424.1 - 5e-11 42.2 0.4 7.9e-08 32.0 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.22 EAK90427.1 - 2.9e-46 157.1 0.0 4.2e-26 91.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAK90427.1 - 2.4e-30 105.8 30.4 9.8e-24 84.2 7.9 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_29 PF13555.1 EAK90427.1 - 3.5e-07 29.6 0.2 0.012 15.1 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 EAK90427.1 - 1e-05 24.8 13.3 0.045 12.9 0.7 4.5 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 EAK90427.1 - 3.7e-05 23.5 0.1 0.12 12.0 0.0 2.7 2 0 0 2 2 2 2 Archaeal ATPase AAA_10 PF12846.2 EAK90427.1 - 0.00012 21.6 0.3 0.35 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.12 EAK90427.1 - 0.00012 21.9 0.1 0.11 12.2 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EAK90427.1 - 0.0002 21.2 0.0 0.021 14.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EAK90427.1 - 0.0018 17.7 0.0 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EAK90427.1 - 0.0024 18.2 3.8 0.1 12.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EAK90427.1 - 0.0071 16.3 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EAK90427.1 - 0.0075 15.4 0.2 3.2 6.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EAK90427.1 - 0.0095 15.3 0.0 3 7.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EAK90427.1 - 0.0096 15.9 0.6 0.0096 15.9 0.4 5.1 6 1 0 6 6 3 1 AAA domain cobW PF02492.14 EAK90427.1 - 0.016 14.6 0.1 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EAK90427.1 - 0.017 14.7 0.0 7.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EAK90427.1 - 0.022 15.2 0.0 0.63 10.5 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 EAK90427.1 - 0.032 14.3 0.5 5.6 7.1 0.0 3.2 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EAK90427.1 - 0.049 12.4 0.1 9 5.0 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.1 EAK90427.1 - 0.073 12.8 0.0 0.74 9.6 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 EAK90427.1 - 0.086 11.9 0.1 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 EAK90427.1 - 0.089 12.4 0.1 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain T2SE PF00437.15 EAK90427.1 - 0.11 11.3 0.1 9.7 4.9 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein TMEMspv1-c74-12 PF11044.3 EAK90428.1 - 0.00049 19.5 0.4 0.0013 18.1 0.3 1.7 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein Big_5 PF13205.1 EAK90429.1 - 9e-11 42.3 0.5 2.8e-07 31.0 0.0 3.6 3 0 0 3 3 3 2 Bacterial Ig-like domain Snf7 PF03357.16 EAK90430.1 - 9.6e-18 64.1 12.5 1.2e-17 63.7 8.7 1.2 1 0 0 1 1 1 1 Snf7 DUF3585 PF12130.3 EAK90430.1 - 0.097 12.5 11.9 0.74 9.6 4.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3585) YlqD PF11068.3 EAK90430.1 - 0.11 12.4 7.8 0.062 13.3 3.6 1.9 1 1 1 2 2 2 0 YlqD protein DUF29 PF01724.11 EAK90430.1 - 0.19 11.5 2.3 0.18 11.6 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF29 Prefoldin_2 PF01920.15 EAK90430.1 - 0.19 11.4 5.8 0.16 11.7 1.9 2.4 2 0 0 2 2 2 0 Prefoldin subunit Nup54 PF13874.1 EAK90430.1 - 0.35 10.5 6.3 1.7 8.2 4.3 2.2 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Lge1 PF11488.3 EAK90430.1 - 1.6 8.9 6.6 0.81 9.9 1.0 2.9 2 1 2 4 4 4 0 Transcriptional regulatory protein LGE1 DUF4140 PF13600.1 EAK90430.1 - 3.4 8.1 6.9 2.5 8.6 1.9 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) LUC7 PF03194.10 EAK90430.1 - 3.6 7.0 7.5 15 5.0 5.2 2.0 1 1 0 1 1 1 0 LUC7 N_terminus K-box PF01486.12 EAK90430.1 - 5 6.9 11.1 0.52 10.1 0.4 2.9 2 1 1 3 3 3 0 K-box region Wbp11 PF09429.5 EAK90430.1 - 5.2 7.1 11.0 5.3 7.0 1.4 3.4 2 1 1 3 3 3 0 WW domain binding protein 11 V_ATPase_I PF01496.14 EAK90430.1 - 5.8 4.6 7.6 6.6 4.4 5.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fzo_mitofusin PF04799.8 EAK90430.1 - 8.6 5.7 7.1 5 6.4 1.0 2.3 1 1 2 3 3 3 0 fzo-like conserved region Methyltrn_RNA_3 PF02598.12 EAK90431.1 - 5.5e-80 268.8 0.0 6.8e-80 268.5 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 EAK90431.1 - 0.00017 21.5 0.0 0.0096 15.7 0.0 2.9 3 0 0 3 3 3 1 SpoU rRNA Methylase family MATH PF00917.21 EAK90431.1 - 0.0053 17.0 1.0 1.7 8.8 0.2 2.4 1 1 1 2 2 2 2 MATH domain DUF1677 PF07911.8 EAK90431.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) DEAD PF00270.24 EAK90432.1 - 2.4e-36 124.7 0.0 2.6e-34 118.1 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK90432.1 - 4e-27 93.8 0.1 1.1e-26 92.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAK90432.1 - 2e-05 24.5 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EAK90432.1 - 0.0092 15.9 0.2 1.1 9.2 0.0 3.0 3 1 0 3 3 3 1 Helicase C-terminal domain DUF1253 PF06862.7 EAK90432.1 - 0.032 12.6 0.1 1.7 6.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) Cyclin_N PF00134.18 EAK90433.1 - 8.6e-07 28.5 0.1 3.9e-06 26.4 0.1 2.0 1 1 0 1 1 1 1 Cyclin, N-terminal domain Rpp20 PF12328.3 EAK90434.1 - 1.1e-17 64.0 0.9 1.1e-17 64.0 0.6 1.6 2 0 0 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EAK90434.1 - 1.1e-13 50.5 0.1 2.3e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 Alba Mucin PF01456.12 EAK90435.1 - 0.0015 18.3 29.3 0.014 15.1 17.8 2.2 2 0 0 2 2 2 2 Mucin-like glycoprotein Hydrolase_6 PF13344.1 EAK90435.1 - 0.0053 16.6 0.1 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF3439 PF11921.3 EAK90435.1 - 0.048 13.4 16.5 0.14 11.8 11.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Adeno_E3_CR2 PF02439.10 EAK90438.1 - 3.9 7.0 7.1 5.7 6.5 4.9 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 AAA PF00004.24 EAK90439.1 - 5.4e-12 46.0 0.0 1.3e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EAK90439.1 - 0.00012 22.4 0.5 0.00052 20.3 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAK90439.1 - 0.00038 20.6 0.2 0.057 13.5 0.1 2.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAK90439.1 - 0.00041 21.1 2.5 0.00068 20.4 0.1 2.7 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EAK90439.1 - 0.0016 18.4 0.0 0.0049 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EAK90439.1 - 0.002 18.0 0.0 0.0088 15.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EAK90439.1 - 0.0075 16.5 1.2 0.019 15.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Herpes_IE1 PF07340.6 EAK90439.1 - 0.01 14.2 0.1 0.017 13.5 0.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein AAA_5 PF07728.9 EAK90439.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EAK90439.1 - 0.015 14.5 0.2 0.058 12.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EAK90439.1 - 0.039 13.8 0.1 0.099 12.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 EAK90439.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin zf-RING_2 PF13639.1 EAK90440.1 - 0.00013 21.7 6.9 0.0002 21.1 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAK90440.1 - 0.053 13.5 7.2 0.29 11.1 5.3 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EAK90440.1 - 0.066 13.2 10.2 0.16 12.0 6.8 1.8 1 1 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 EAK90440.1 - 0.53 10.0 8.3 0.28 10.9 3.9 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 EAK90440.1 - 0.72 9.5 9.7 0.28 10.9 4.1 2.0 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_3 PF13920.1 EAK90440.1 - 1.1 8.9 8.0 2.2 7.9 5.6 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) START PF01852.14 EAK90441.1 - 0.0014 17.9 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 START domain GDI PF00996.13 EAK90443.1 - 3.7e-47 160.6 3.2 3e-26 91.7 0.1 2.7 2 1 1 3 3 3 2 GDP dissociation inhibitor DAO PF01266.19 EAK90443.1 - 0.019 13.9 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAK90443.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain RNA_pol_Rpb6 PF01192.17 EAK90445.1 - 8.7e-21 73.4 0.1 8.7e-21 73.4 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb6 GST_N PF02798.15 EAK90446.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PP2C PF00481.16 EAK90447.1 - 5.2e-07 29.3 0.0 0.033 13.5 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EAK90447.1 - 6.1e-06 26.0 0.0 0.00041 20.1 0.0 3.3 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PA14 PF07691.7 EAK90448.1 - 8.5e-24 83.8 0.0 1.9e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 PA14 domain FliJ PF02050.11 EAK90448.1 - 0.054 13.5 4.3 0.91 9.5 0.3 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein HSBP1 PF06825.7 EAK90448.1 - 0.094 12.2 0.2 7.5 6.2 0.2 2.9 2 1 1 3 3 3 0 Heat shock factor binding protein 1 BLOC1_2 PF10046.4 EAK90448.1 - 0.11 12.6 1.9 0.42 10.7 1.1 2.1 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.1 EAK90448.1 - 0.22 11.4 1.9 0.48 10.3 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) MS_channel PF00924.13 EAK90449.1 - 5e-18 65.1 1.6 1.1e-17 64.0 1.1 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel DNA_pol_phi PF04931.8 EAK90450.1 - 0.007 14.2 1.7 0.011 13.5 1.2 1.2 1 0 0 1 1 1 1 DNA polymerase phi zf-C3HC4_2 PF13923.1 EAK90450.1 - 0.085 12.8 3.3 0.28 11.2 2.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Phosducin PF02114.11 EAK90451.1 - 4e-11 42.1 0.3 5.8e-11 41.6 0.2 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EAK90451.1 - 0.0026 17.4 0.0 0.007 16.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin zf-RING_2 PF13639.1 EAK90453.1 - 2.6e-14 52.7 3.7 5.5e-14 51.7 2.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAK90453.1 - 5.1e-09 36.1 1.1 1.3e-08 34.8 0.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EAK90453.1 - 2.4e-07 30.6 4.9 5.6e-07 29.4 3.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAK90453.1 - 1.4e-06 27.8 4.5 3.5e-06 26.5 3.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK90453.1 - 1.1e-05 25.0 3.5 2.5e-05 23.9 2.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAK90453.1 - 8.3e-05 22.1 1.7 0.00017 21.2 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EAK90453.1 - 0.00057 19.5 1.1 0.0031 17.2 0.1 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 EAK90453.1 - 0.014 14.9 2.5 0.031 13.8 1.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EAK90453.1 - 0.039 13.7 2.7 0.12 12.2 1.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FtsL PF04999.8 EAK90453.1 - 0.078 12.6 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Cell division protein FtsL FANCL_C PF11793.3 EAK90453.1 - 0.17 11.8 4.5 0.85 9.6 3.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain UPF0547 PF10571.4 EAK90453.1 - 0.18 11.5 1.6 12 5.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 RINGv PF12906.2 EAK90453.1 - 0.28 11.2 5.1 0.76 9.8 3.5 1.8 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EAK90453.1 - 0.28 10.9 3.5 0.56 9.9 2.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger UCH PF00443.24 EAK90454.1 - 2.4e-22 79.3 11.9 2.4e-22 79.3 8.2 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF4597 PF15366.1 EAK90455.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Alg14 PF08660.6 EAK90456.1 - 2.4e-31 109.0 0.0 2.9e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Peptidase_M27 PF01742.12 EAK90456.1 - 0.018 13.9 0.4 0.021 13.6 0.3 1.1 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease Aldedh PF00171.17 EAK90457.1 - 1.3e-14 53.3 0.0 3.1e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Fumble PF03630.9 EAK90458.1 - 6.7e-40 136.9 7.6 1.6e-39 135.7 5.3 1.6 1 1 0 1 1 1 1 Fumble DUF3924 PF13062.1 EAK90458.1 - 0.0045 16.8 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3924) zf-RING_4 PF14570.1 EAK90459.1 - 2.6e-19 68.5 16.8 7.9e-19 66.9 11.6 1.9 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 EAK90459.1 - 6e-09 35.6 0.2 1.6e-08 34.2 0.2 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAK90459.1 - 8.4e-09 34.9 0.6 1.8e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EAK90459.1 - 3.6e-06 26.5 8.8 9.2e-06 25.2 6.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 EAK90459.1 - 6.2e-06 26.0 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 EAK90459.1 - 0.00082 19.1 11.5 0.003 17.3 7.9 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAK90459.1 - 5.2 7.1 19.8 0.074 13.0 8.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) EF-hand_7 PF13499.1 EAK90460.1 - 2.2e-07 30.8 15.5 1.1e-05 25.5 7.7 4.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EAK90460.1 - 5.7e-05 22.6 3.1 0.042 13.7 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EAK90460.1 - 0.00015 20.8 6.3 0.041 13.2 0.3 4.3 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.1 EAK90460.1 - 0.02 14.2 0.1 0.1 11.9 0.0 2.3 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 EAK90460.1 - 7.7 6.2 8.2 3.5 7.3 0.2 3.4 3 0 0 3 3 3 0 EF-hand domain pair HECT PF00632.20 EAK90462.1 - 8.3e-46 156.5 0.0 3.2e-45 154.6 0.0 2.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.2 EAK90462.1 - 3.3e-08 33.7 0.0 4.1e-05 23.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAK90462.1 - 4.2e-07 30.3 0.1 0.0044 17.5 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EAK90462.1 - 0.00019 21.0 0.1 0.88 9.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EAK90462.1 - 0.00054 19.9 0.1 1.4 9.3 0.0 3.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EAK90462.1 - 0.0037 17.4 0.3 0.2 11.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) ubiquitin PF00240.18 EAK90463.1 - 4.2e-08 32.4 0.1 1.1e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family UBA PF00627.26 EAK90463.1 - 7e-07 28.9 0.0 2.8e-06 26.9 0.0 2.2 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EAK90463.1 - 0.00056 19.5 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.6 EAK90463.1 - 4.3 6.8 15.7 0.14 11.6 0.6 4.1 3 1 1 4 4 4 0 XPC-binding domain Rgp1 PF08737.5 EAK90464.1 - 3.2e-09 36.3 0.7 3.2e-09 36.3 0.5 2.7 2 1 0 2 2 2 1 Rgp1 Ribophorin_II PF05817.9 EAK90466.1 - 2.4e-06 26.1 4.7 2.4e-06 26.1 3.2 1.7 2 0 0 2 2 2 1 Oligosaccharyltransferase subunit Ribophorin II Thioredoxin PF00085.15 EAK90467.1 - 1.1e-24 86.0 1.0 4.7e-16 58.3 0.2 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EAK90467.1 - 5.6e-18 65.3 9.6 1e-11 44.9 0.1 4.3 2 1 2 4 4 4 3 Thioredoxin-like domain AhpC-TSA PF00578.16 EAK90467.1 - 1.3e-05 24.8 0.2 0.015 15.0 0.0 2.8 3 0 0 3 3 3 2 AhpC/TSA family DUF836 PF05768.9 EAK90467.1 - 8e-05 22.8 0.3 0.053 13.7 0.2 2.7 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 EAK90467.1 - 0.0013 18.8 1.7 0.19 11.9 0.2 4.0 3 2 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 EAK90467.1 - 0.0027 17.2 0.1 5.3 6.5 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_8 PF13905.1 EAK90467.1 - 0.0065 16.5 2.1 0.11 12.6 0.1 3.7 4 1 0 4 4 4 1 Thioredoxin-like Redoxin PF08534.5 EAK90467.1 - 0.11 12.0 0.0 5.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Redoxin CBM_14 PF01607.19 EAK90472.1 - 2.3e-05 24.1 55.2 0.19 11.6 1.7 12.7 3 3 10 13 13 13 8 Chitin binding Peritrophin-A domain Phage_gp49_66 PF13876.1 EAK90472.1 - 0.087 12.9 0.1 3.7 7.7 0.0 2.9 2 0 0 2 2 2 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family cEGF PF12662.2 EAK90472.1 - 0.36 10.5 14.3 2.8 7.6 0.0 6.4 7 0 0 7 7 7 0 Complement Clr-like EGF-like dUTPase PF00692.14 EAK90473.1 - 3.6e-15 55.5 0.0 4.9e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 dUTPase JAB PF01398.16 EAK90474.1 - 0.0029 17.3 0.1 0.98 9.1 0.0 2.5 2 0 0 2 2 2 2 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AAA_17 PF13207.1 EAK90476.1 - 0.013 16.2 0.0 0.091 13.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain Bromodomain PF00439.20 EAK90477.1 - 2.7e-18 65.6 0.1 7.8e-18 64.1 0.0 1.8 2 0 0 2 2 2 1 Bromodomain RRM_1 PF00076.17 EAK90478.1 - 1.4e-28 98.3 5.6 2.2e-14 52.8 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK90478.1 - 4.5e-23 80.8 2.0 3.4e-08 33.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK90478.1 - 6e-22 77.4 0.8 4.9e-11 42.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EAK90478.1 - 0.0023 18.1 0.6 1 9.7 0.1 2.8 2 0 0 2 2 2 2 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 EAK90478.1 - 0.013 15.3 0.3 0.08 12.8 0.0 2.5 2 1 0 2 2 2 0 RNA binding motif HAD PF12710.2 EAK90479.1 - 3.2e-05 24.2 0.0 5.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sec3-PIP2_bind PF15277.1 EAK90480.1 - 0.031 14.1 0.8 0.12 12.3 0.2 2.2 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH SSrecog PF03531.9 EAK90481.1 - 4.6e-54 183.0 0.0 7.2e-54 182.4 0.0 1.2 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EAK90481.1 - 1e-27 95.9 0.3 5.4e-26 90.4 0.0 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Hint PF01079.15 EAK90482.1 - 6e-24 84.4 0.0 9e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.1 EAK90482.1 - 0.00037 20.4 0.0 0.0019 18.1 0.0 2.1 2 0 0 2 2 2 1 Hint domain DUF1317 PF07026.6 EAK90482.1 - 0.056 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) DNA_ligase_OB PF03120.11 EAK90482.1 - 0.13 11.9 0.5 2.1 8.0 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase OB-fold domain E1-E2_ATPase PF00122.15 EAK90482.1 - 0.17 10.8 1.0 1.2 8.1 0.1 2.3 3 0 0 3 3 3 0 E1-E2 ATPase PPTA PF01239.17 EAK90483.1 - 3.1e-26 89.5 26.4 2e-07 30.0 0.3 6.8 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat HSA PF07529.8 EAK90483.1 - 0.42 10.4 2.1 0.41 10.4 0.2 1.9 2 0 0 2 2 2 0 HSA FYVE PF01363.16 EAK90484.1 - 1.3 9.0 13.1 0.66 9.9 6.0 2.4 1 1 1 2 2 2 0 FYVE zinc finger AKAP7_NLS PF10469.4 EAK90487.1 - 1.2e-27 96.9 1.3 2.1e-27 96.2 0.9 1.4 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.11 EAK90487.1 - 1.1e-05 25.2 0.0 0.06 13.3 0.1 3.4 2 1 0 2 2 2 1 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.1 EAK90487.1 - 0.00016 21.3 0.0 0.0012 18.6 0.0 2.2 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily WD40 PF00400.27 EAK90489.1 - 1.6e-19 68.9 6.9 2.8e-05 23.8 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat SAE2 PF08573.5 EAK90492.1 - 5.7e-12 46.1 2.1 5.7e-12 46.1 1.4 2.4 2 1 1 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Herpes_BLRF2 PF05812.7 EAK90492.1 - 0.0013 18.5 0.8 0.0013 18.5 0.5 1.9 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein CCDC92 PF14916.1 EAK90492.1 - 0.011 15.2 2.8 0.015 14.8 0.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain of unknown function CarD_CdnL_TRCF PF02559.11 EAK90492.1 - 0.057 13.4 1.9 0.79 9.7 0.0 2.5 2 1 0 2 2 2 0 CarD-like/TRCF domain HALZ PF02183.13 EAK90492.1 - 0.076 12.7 0.5 0.21 11.3 0.3 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper NUDE_C PF04880.8 EAK90492.1 - 0.42 10.9 10.7 1.4 9.2 7.4 2.0 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF1767 PF08585.7 EAK90493.1 - 3.8e-14 52.7 0.4 1.8e-13 50.5 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1767) DUF3994 PF13159.1 EAK90495.1 - 3.3 7.9 6.4 18 5.6 0.2 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3994) Vps16_N PF04841.8 EAK90497.1 - 4.3e-38 130.9 0.0 9.6e-38 129.7 0.0 1.6 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EAK90497.1 - 1.4e-21 76.8 5.1 1.6e-11 43.7 0.4 2.7 1 1 1 2 2 2 2 Vps16, C-terminal region PPR_3 PF13812.1 EAK90497.1 - 0.081 13.2 0.0 11 6.6 0.0 2.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain DUF2213 PF09979.4 EAK90499.1 - 0.006 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2213) GPS PF01825.16 EAK90500.1 - 0.01 15.8 1.6 0.027 14.5 1.1 1.7 1 0 0 1 1 1 0 Latrophilin/CL-1-like GPS domain Glyco_trans_1_3 PF13528.1 EAK90500.1 - 0.21 10.7 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Val_tRNA-synt_C PF10458.4 EAK90501.1 - 0.36 10.9 4.6 0.24 11.5 0.4 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF919 PF06034.6 EAK90501.1 - 1.7 8.3 9.7 1 9.0 2.0 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Enkurin PF13864.1 EAK90501.1 - 1.8 8.7 8.3 0.42 10.8 1.6 2.5 1 1 1 2 2 2 0 Calmodulin-binding TFIIE_beta PF02186.10 EAK90501.1 - 8.3 6.4 9.1 3.4 7.7 0.1 3.2 4 0 0 4 4 4 0 TFIIE beta subunit core domain CTP_transf_1 PF01148.15 EAK90504.1 - 1.6e-70 237.7 20.9 2.2e-70 237.3 14.5 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family DUF373 PF04123.8 EAK90504.1 - 0.18 10.7 7.5 0.053 12.5 3.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Tetraspannin PF00335.15 EAK90505.1 - 0.039 13.2 10.9 2.1 7.5 7.5 2.1 1 1 0 1 1 1 0 Tetraspanin family Lum_binding PF00677.12 EAK90505.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Lumazine binding domain TRIQK PF15168.1 EAK90505.1 - 0.15 12.0 2.0 3.6 7.5 0.1 2.5 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family EOS1 PF12326.3 EAK90505.1 - 0.39 10.3 7.4 0.32 10.6 4.2 1.6 1 1 0 1 1 1 0 N-glycosylation protein TB2_DP1_HVA22 PF03134.14 EAK90505.1 - 0.45 10.2 7.4 2.6 7.8 3.5 2.5 2 1 0 2 2 2 0 TB2/DP1, HVA22 family DUF3464 PF11947.3 EAK90505.1 - 1.3 8.4 8.0 0.082 12.3 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) VIT1 PF01988.14 EAK90508.1 - 0.027 13.9 0.0 0.031 13.7 0.0 1.0 1 0 0 1 1 1 0 VIT family Hat1_N PF10394.4 EAK90509.1 - 7.6e-27 94.3 1.0 1.4e-26 93.5 0.7 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 EAK90509.1 - 0.028 14.5 0.1 0.095 12.8 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EAK90509.1 - 0.036 13.2 0.3 0.072 12.3 0.0 1.6 2 0 0 2 2 2 0 MOZ/SAS family zf-C3HC4_3 PF13920.1 EAK90510.1 - 4.9e-06 26.1 9.6 4.9e-06 26.1 6.6 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAK90510.1 - 0.00023 21.1 9.1 0.00023 21.1 6.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ATP_bind_1 PF03029.12 EAK90511.1 - 3.5e-70 236.2 0.0 4e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 EAK90511.1 - 0.00027 20.8 0.0 0.00033 20.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EAK90511.1 - 0.0016 17.8 0.0 0.022 14.2 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EAK90511.1 - 0.002 17.6 0.0 0.0034 16.8 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain AAA_18 PF13238.1 EAK90511.1 - 0.0023 18.2 0.0 0.0064 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAK90511.1 - 0.0045 17.7 0.1 0.0097 16.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EAK90511.1 - 0.0047 16.1 0.6 2.1 7.5 0.0 3.0 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EAK90511.1 - 0.0055 16.6 0.1 0.016 15.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 EAK90511.1 - 0.0073 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_21 PF13304.1 EAK90511.1 - 0.013 15.4 1.6 0.31 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EAK90511.1 - 0.014 15.6 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EAK90511.1 - 0.016 14.9 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 EAK90511.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAK90511.1 - 0.036 14.2 0.0 0.21 11.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EAK90511.1 - 0.04 13.5 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KTI12 PF08433.5 EAK90511.1 - 0.055 12.6 0.0 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_23 PF13476.1 EAK90511.1 - 0.063 13.6 0.0 0.23 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EAK90511.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 EAK90511.1 - 0.098 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EAK90511.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EAK90511.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin BNR PF02012.15 EAK90512.1 - 0.00038 19.8 12.1 0.39 10.7 0.1 6.6 7 0 0 7 7 7 2 BNR/Asp-box repeat UCR_UQCRX_QCR9 PF05365.7 EAK90512.1 - 0.78 9.4 5.3 0.51 10.0 0.1 2.9 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like SprT-like PF10263.4 EAK90513.1 - 2.2e-27 95.6 0.8 3.6e-27 94.9 0.5 1.4 1 0 0 1 1 1 1 SprT-like family Zn-ribbon_8 PF09723.5 EAK90513.1 - 0.00044 20.1 0.7 0.0011 18.8 0.5 1.7 1 0 0 1 1 1 1 Zinc ribbon domain DUF1186 PF06685.6 EAK90514.1 - 0.011 14.9 0.2 0.017 14.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1186) FKBP_C PF00254.23 EAK90516.1 - 2e-24 85.4 0.3 1.1e-23 83.0 0.0 2.2 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase OTU PF02338.14 EAK90517.1 - 0.00033 21.2 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 2 OTU-like cysteine protease RNase_PH PF01138.16 EAK90518.1 - 1.2e-12 48.2 0.1 2.2e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EAK90518.1 - 8.1e-05 22.4 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1253 PF06862.7 EAK90520.1 - 1.4e-149 498.2 0.1 2.2e-149 497.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Amino_oxidase PF01593.19 EAK90521.1 - 3.6e-26 92.2 0.0 1.8e-11 43.8 0.0 3.3 3 0 0 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EAK90521.1 - 2.4e-07 30.6 0.0 6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAK90521.1 - 1.7e-05 23.9 0.0 3.7e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EAK90521.1 - 0.00059 18.4 0.1 0.001 17.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EAK90521.1 - 0.00067 18.8 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EAK90521.1 - 0.00096 18.0 0.1 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EAK90521.1 - 0.0012 17.8 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EAK90521.1 - 0.0016 18.3 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAK90521.1 - 0.0019 18.3 0.0 0.034 14.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAK90521.1 - 0.0021 17.1 0.1 0.0033 16.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EAK90521.1 - 0.0062 16.9 0.1 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAK90521.1 - 0.048 13.4 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EAK90521.1 - 0.059 12.2 0.6 0.12 11.1 0.1 1.8 1 1 1 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EAK90521.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EAK90521.1 - 0.47 9.4 0.0 0.7 8.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase LCCL PF03815.14 EAK90522.1 - 4.1e-21 74.7 0.1 4.1e-21 74.7 0.1 3.0 2 0 0 2 2 2 1 LCCL domain F5_F8_type_C PF00754.20 EAK90522.1 - 7.3e-11 42.0 2.4 2.4e-06 27.3 0.5 2.6 2 0 0 2 2 2 2 F5/8 type C domain DUF1080 PF06439.6 EAK90522.1 - 0.00058 19.8 1.5 0.0078 16.1 0.0 2.9 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1080) Rxt3 PF08642.5 EAK90522.1 - 0.03 14.5 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Rad21_Rec8_N PF04825.8 EAK90523.1 - 3.5e-21 75.2 0.1 9.1e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EAK90523.1 - 9.6e-08 31.8 0.1 9.6e-08 31.8 0.0 2.3 3 0 0 3 3 3 1 ScpA/B protein Rad21_Rec8 PF04824.11 EAK90523.1 - 9.1e-07 27.9 0.0 2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein AAA_18 PF13238.1 EAK90524.1 - 3.1e-08 33.9 0.6 1.5e-07 31.7 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAK90524.1 - 4.3e-08 34.0 0.4 3.3e-07 31.1 0.1 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EAK90524.1 - 1.2e-06 27.7 0.1 3.8e-06 26.1 0.1 1.8 1 1 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EAK90524.1 - 5.1e-06 26.4 0.0 1.2e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EAK90524.1 - 0.00026 20.6 1.3 0.00082 18.9 0.9 1.9 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Cytidylate_kin2 PF13189.1 EAK90524.1 - 0.00056 19.8 1.0 0.00056 19.8 0.7 2.0 3 0 0 3 3 2 1 Cytidylate kinase-like family AAA_29 PF13555.1 EAK90524.1 - 0.0007 19.0 0.1 0.0025 17.3 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EAK90524.1 - 0.0013 18.7 0.1 0.0019 18.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 EAK90524.1 - 0.0022 17.9 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EAK90524.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.13 EAK90524.1 - 0.0097 15.3 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EAK90524.1 - 0.014 15.5 1.0 0.057 13.5 0.7 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAK90524.1 - 0.015 15.5 0.8 0.029 14.6 0.6 1.7 1 1 0 1 1 1 0 ABC transporter SKI PF01202.17 EAK90524.1 - 0.018 14.8 2.7 0.62 9.9 0.0 2.5 2 1 0 2 2 2 0 Shikimate kinase T2SE PF00437.15 EAK90524.1 - 0.027 13.3 1.5 0.097 11.5 0.4 2.2 1 1 1 2 2 2 0 Type II/IV secretion system protein CoaE PF01121.15 EAK90524.1 - 0.043 13.2 0.1 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Dephospho-CoA kinase HTH_36 PF13730.1 EAK90524.1 - 0.044 13.9 0.4 5.4 7.2 0.1 3.1 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_5 PF07728.9 EAK90524.1 - 0.059 13.1 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EAK90524.1 - 0.076 13.1 2.6 0.2 11.8 1.0 2.4 2 1 0 2 2 2 0 RNA helicase MobB PF03205.9 EAK90524.1 - 0.089 12.5 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EAK90524.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CPT PF07931.7 EAK90524.1 - 0.11 12.1 0.2 0.21 11.1 0.1 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF258 PF03193.11 EAK90524.1 - 0.11 11.6 3.3 0.099 11.8 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF258 CbiA PF01656.18 EAK90524.1 - 0.12 11.7 2.3 0.26 10.6 1.5 1.8 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.10 EAK90524.1 - 0.14 11.8 4.3 2.9 7.5 0.2 2.7 1 1 0 2 2 2 0 NTPase Ribosomal_L18ae PF01775.12 EAK90525.1 - 7.4e-50 167.9 1.2 9.4e-50 167.6 0.9 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain GLE1 PF07817.8 EAK90526.1 - 1.5e-18 66.6 0.6 1.5e-18 66.6 0.4 3.3 1 1 2 3 3 3 1 GLE1-like protein AF2331-like PF14556.1 EAK90526.1 - 0.051 13.9 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 AF2331-like eIF3_subunit PF08597.5 EAK90526.1 - 0.66 9.4 37.9 0.44 10.0 25.0 1.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit GRASP55_65 PF04495.9 EAK90527.1 - 6.4e-40 136.3 0.0 1.2e-32 112.7 0.0 2.5 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PDZ PF00595.19 EAK90527.1 - 0.0037 17.4 0.1 1.4 9.1 0.0 3.1 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EAK90527.1 - 0.008 16.0 0.2 0.036 13.9 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Virulence_fact PF13769.1 EAK90528.1 - 0.055 13.3 0.6 6.2 6.7 0.0 2.6 2 0 0 2 2 2 0 Virulence factor HSP70 PF00012.15 EAK90529.1 - 8e-262 869.5 13.1 9.2e-262 869.3 9.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EAK90529.1 - 3e-17 62.2 3.1 2.2e-16 59.3 1.4 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EAK90529.1 - 0.023 13.8 2.1 0.32 10.0 0.1 3.1 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase Ribosomal_S6 PF01250.12 EAK90529.1 - 0.22 11.4 3.4 3.3 7.6 0.0 3.9 4 0 0 4 4 4 0 Ribosomal protein S6 StbA PF06406.6 EAK90529.1 - 0.29 10.0 4.3 0.088 11.7 0.2 2.2 2 1 0 2 2 2 0 StbA protein Effector_1 PF04518.7 EAK90529.1 - 0.71 8.8 6.2 0.9 8.4 0.1 2.2 2 0 0 2 2 2 0 Effector from type III secretion system FtsA PF14450.1 EAK90529.1 - 1.9 8.3 9.9 0.69 9.7 0.0 3.8 3 1 0 3 3 3 0 Cell division protein FtsA Abhydrolase_5 PF12695.2 EAK90530.1 - 2.6e-17 62.9 0.0 4.5e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAK90530.1 - 2.8e-12 47.0 0.0 7.9e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EAK90530.1 - 7.9e-09 35.3 0.0 1.1e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 EAK90530.1 - 1.5e-05 24.5 0.0 4.1e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PhoPQ_related PF10142.4 EAK90530.1 - 3.2e-05 22.5 0.0 4.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_1 PF00561.15 EAK90530.1 - 7.6e-05 22.3 1.3 0.0027 17.2 0.4 2.3 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAK90530.1 - 0.0023 17.1 0.1 0.023 13.9 0.1 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family PAF-AH_p_II PF03403.8 EAK90530.1 - 0.039 12.2 0.0 0.23 9.7 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.7 EAK90530.1 - 0.056 11.9 0.0 0.8 8.1 0.0 2.3 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 EAK90530.1 - 0.062 13.0 0.0 0.25 11.0 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal SNF2_N PF00176.18 EAK90533.1 - 3.1e-37 128.0 0.0 3.1e-37 128.0 0.0 4.9 5 0 0 5 5 5 2 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EAK90533.1 - 9e-07 28.6 6.6 9e-07 28.6 4.6 3.1 2 0 0 2 2 2 1 Ring finger domain Helicase_C PF00271.26 EAK90533.1 - 6.6e-06 25.9 1.3 3.7e-05 23.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EAK90533.1 - 2.4e-05 23.9 8.1 2.4e-05 23.9 5.6 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAK90533.1 - 5.3e-05 23.1 9.9 5.3e-05 23.1 6.8 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EAK90533.1 - 6.7e-05 22.3 6.5 6.7e-05 22.3 4.5 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 EAK90533.1 - 0.00038 20.0 11.0 0.00038 20.0 7.6 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAK90533.1 - 0.0019 17.8 7.6 0.0098 15.5 5.3 2.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EAK90533.1 - 0.0086 15.5 4.3 0.066 12.7 3.0 2.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 E1-E2_ATPase PF00122.15 EAK90534.1 - 1.5e-18 66.7 0.2 3.6e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EAK90534.1 - 4.5e-16 59.5 0.0 1.2e-15 58.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAK90534.1 - 5.2e-14 53.1 0.6 2.5e-12 47.6 0.4 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAK90534.1 - 1.2e-08 34.7 0.1 2.3e-07 30.6 0.0 2.6 2 1 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF1381 PF07129.6 EAK90535.1 - 0.12 11.7 1.8 0.25 10.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1381) DUF334 PF03904.8 EAK90535.1 - 6.5 6.0 10.5 0.48 9.7 3.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF334) RPAP2_Rtr1 PF04181.8 EAK90536.1 - 5.2e-12 45.6 0.2 5.2e-12 45.6 0.1 3.1 4 0 0 4 4 4 1 Rtr1/RPAP2 family Pro_isomerase PF00160.16 EAK90537.1 - 4e-49 166.7 0.1 1.5e-48 164.9 0.1 2.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EAK90537.1 - 1.1e-10 40.8 0.0 0.024 14.5 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EAK90537.1 - 0.0068 15.2 4.6 0.034 12.9 0.1 2.4 1 1 1 2 2 2 1 Nup133 N terminal like PIG-U PF06728.8 EAK90538.1 - 4.4e-47 160.7 54.5 5.5e-47 160.4 37.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF3099 PF11298.3 EAK90539.1 - 0.76 9.5 3.7 5.6 6.7 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3099) TPR_11 PF13414.1 EAK90540.1 - 6.9e-14 51.2 2.2 1.3e-11 43.9 0.0 2.7 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EAK90540.1 - 8.2e-07 28.3 2.6 3.9e-05 23.0 0.1 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAK90540.1 - 2e-05 24.1 0.4 0.0063 16.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EAK90540.1 - 9.5e-05 22.2 1.7 0.006 16.4 0.2 2.5 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain DUF3808 PF10300.4 EAK90540.1 - 0.00014 20.5 0.6 0.00019 20.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Apc3 PF12895.2 EAK90540.1 - 0.0014 18.7 2.1 0.0033 17.5 1.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EAK90540.1 - 0.022 14.9 1.5 2.2 8.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAK90540.1 - 0.026 15.2 0.9 11 6.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAK90540.1 - 0.082 12.7 3.9 0.28 11.0 0.3 2.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF3552 PF12072.3 EAK90540.1 - 0.098 11.8 5.6 0.17 11.1 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF919 PF06034.6 EAK90540.1 - 0.59 9.8 5.2 1.5 8.5 3.6 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) IRF PF00605.12 EAK90542.1 - 0.022 14.5 3.0 0.029 14.1 2.1 1.1 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor SH3BGR PF04908.10 EAK90542.1 - 0.53 10.2 2.3 3.5 7.6 0.6 2.1 1 1 1 2 2 2 0 SH3-binding, glutamic acid-rich protein Pkinase PF00069.20 EAK90543.1 - 8.9e-06 25.0 0.1 1.1e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK90543.1 - 0.0002 20.5 0.0 0.00025 20.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAK90543.1 - 0.12 11.3 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CRAL_TRIO PF00650.15 EAK90545.1 - 3e-28 98.2 0.4 5.6e-28 97.4 0.3 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Methyltransf_11 PF08241.7 EAK90546.1 - 2e-13 50.6 0.0 4.1e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAK90546.1 - 2.4e-09 37.1 0.0 3.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAK90546.1 - 2.9e-08 33.9 0.3 7.3e-08 32.6 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAK90546.1 - 3e-08 34.0 0.0 5.8e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAK90546.1 - 1e-06 28.4 0.1 2.7e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 EAK90546.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 EAK90546.1 - 0.0028 16.4 0.0 0.011 14.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.6 EAK90546.1 - 0.0038 16.6 0.0 0.0097 15.3 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_18 PF12847.2 EAK90546.1 - 0.01 16.3 0.2 0.035 14.6 0.2 1.9 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EAK90546.1 - 0.031 13.3 0.0 0.093 11.7 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EAK90546.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HA2 PF04408.18 EAK90547.1 - 6.2e-27 93.6 0.0 2.9e-26 91.4 0.0 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EAK90547.1 - 1.3e-20 73.3 0.1 3e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EAK90547.1 - 7.3e-11 41.7 0.0 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAK90547.1 - 9.3e-06 25.2 0.0 2.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAK90547.1 - 2e-05 24.7 0.0 6.7e-05 23.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain T2SE PF00437.15 EAK90547.1 - 7e-05 21.8 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 EAK90547.1 - 0.004 16.1 0.0 0.0072 15.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EAK90547.1 - 0.0085 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EAK90547.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain SRP54 PF00448.17 EAK90547.1 - 0.02 14.3 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.1 EAK90547.1 - 0.047 13.7 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain Miro PF08477.8 EAK90547.1 - 0.048 14.1 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_19 PF13245.1 EAK90547.1 - 0.05 13.3 0.1 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Cyclin_N PF00134.18 EAK90548.1 - 8.9e-05 22.0 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_N PF00134.18 EAK90549.1 - 2.1e-10 40.2 1.0 1.6e-06 27.7 0.0 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EAK90549.1 - 5.5e-07 29.5 0.1 1.1e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain SNARE PF05739.14 EAK90550.1 - 1.1e-12 47.4 1.5 5.9e-12 45.0 0.3 2.7 3 0 0 3 3 2 1 SNARE domain Baculo_PEP_C PF04513.7 EAK90550.1 - 0.0015 18.3 4.4 0.61 9.9 0.1 2.6 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.6 EAK90550.1 - 0.0028 18.0 11.5 0.078 13.3 0.1 3.4 2 1 1 3 3 3 1 Syntaxin 6, N-terminal MCPsignal PF00015.16 EAK90550.1 - 0.0036 16.8 3.4 0.23 10.9 0.4 2.2 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Rootletin PF15035.1 EAK90550.1 - 0.013 15.4 5.8 0.013 15.4 4.0 2.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Prominin PF05478.6 EAK90550.1 - 0.014 13.0 5.2 0.25 8.8 0.1 2.1 2 0 0 2 2 2 0 Prominin IFT57 PF10498.4 EAK90550.1 - 0.021 13.5 17.2 0.043 12.5 0.6 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 PGA2 PF07543.7 EAK90550.1 - 0.024 14.4 3.7 0.058 13.1 2.5 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 LOH1CR12 PF10158.4 EAK90550.1 - 0.045 13.5 2.9 0.075 12.8 0.3 2.2 2 0 0 2 2 2 0 Tumour suppressor protein HSBP1 PF06825.7 EAK90550.1 - 0.048 13.2 2.2 0.39 10.3 0.0 2.9 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF948 PF06103.6 EAK90550.1 - 0.048 13.5 3.4 5.5 6.9 0.2 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GGDEF PF00990.16 EAK90550.1 - 0.063 12.8 1.9 0.95 9.0 0.2 2.3 2 0 0 2 2 2 0 GGDEF domain Imm5 PF14423.1 EAK90550.1 - 0.097 12.2 3.5 0.1 12.2 0.4 2.2 2 0 0 2 2 2 0 Immunity protein Imm5 Laminin_II PF06009.7 EAK90550.1 - 0.3 10.8 7.7 2.5 7.8 1.8 2.7 2 1 0 2 2 2 0 Laminin Domain II DUF904 PF06005.7 EAK90550.1 - 0.32 11.3 0.0 0.32 11.3 0.0 4.0 3 1 0 3 3 2 0 Protein of unknown function (DUF904) NusB PF01029.13 EAK90550.1 - 0.73 9.8 6.3 26 4.7 3.6 2.9 1 1 0 1 1 1 0 NusB family Lipoprotein_7 PF01540.11 EAK90550.1 - 0.82 8.6 7.3 4.2 6.3 1.7 2.3 2 1 0 2 2 2 0 Adhesin lipoprotein Fib_alpha PF08702.5 EAK90550.1 - 1 9.4 15.9 0.18 11.8 1.1 3.2 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family ACCA PF03255.9 EAK90550.1 - 1.2 8.6 5.1 2.8 7.5 1.1 2.8 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TMF_DNA_bd PF12329.3 EAK90550.1 - 1.4 8.8 13.2 0.22 11.3 1.9 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 EAK90550.1 - 1.4 9.0 9.9 0.25 11.4 0.7 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 EAK90550.1 - 1.5 8.8 8.4 4 7.3 1.0 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Cortex-I_coil PF09304.5 EAK90550.1 - 1.8 8.6 13.3 10 6.1 0.1 3.2 2 1 1 3 3 3 0 Cortexillin I, coiled coil CCDC155 PF14662.1 EAK90550.1 - 1.9 8.0 13.9 3.8 7.0 0.1 2.6 2 1 0 3 3 3 0 Coiled-coil region of CCDC155 Seryl_tRNA_N PF02403.17 EAK90550.1 - 4.1 7.4 10.5 1.5 8.9 2.1 3.1 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Orthopox_A5L PF06193.6 EAK90550.1 - 4.5 7.1 11.0 6.9 6.5 0.7 2.5 2 1 0 2 2 2 0 Orthopoxvirus A5L protein-like DUF1298 PF06974.8 EAK90551.1 - 7.4e-06 25.8 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) PerB PF06590.6 EAK90551.1 - 0.045 14.0 1.0 4.3 7.6 0.2 2.6 2 0 0 2 2 2 0 PerB protein KH_1 PF00013.24 EAK90552.1 - 7e-15 54.4 5.1 1.9e-10 40.2 1.5 2.7 3 0 0 3 3 3 2 KH domain KH_3 PF13014.1 EAK90552.1 - 2.3e-10 39.8 5.3 2.2e-08 33.5 2.1 3.2 3 0 0 3 3 3 2 KH domain Helicase_C PF00271.26 EAK90553.1 - 0.021 14.6 0.5 0.1 12.4 0.0 2.4 2 0 0 2 2 2 0 Helicase conserved C-terminal domain BrkDBD PF09607.5 EAK90554.1 - 0.044 13.3 0.1 0.21 11.1 0.1 2.1 1 1 0 1 1 1 0 Brinker DNA-binding domain Het-C PF07217.6 EAK90554.1 - 0.059 11.5 0.0 0.08 11.1 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C TRP PF06011.7 EAK90555.1 - 0.024 13.2 0.0 0.03 12.8 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Nexin_C PF08628.7 EAK90556.1 - 0.044 13.8 1.4 0.64 10.1 0.3 3.2 3 0 0 3 3 3 0 Sorting nexin C terminal RRM_1 PF00076.17 EAK90557.1 - 1.2e-34 117.6 1.1 1.8e-16 59.4 0.1 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK90557.1 - 3.4e-25 87.8 0.5 6.9e-13 48.3 0.1 2.9 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK90557.1 - 8.1e-16 57.6 3.5 7.8e-09 35.2 0.1 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1127 PF06568.6 EAK90557.1 - 0.21 11.0 0.1 0.42 10.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) TGT PF01702.13 EAK90561.1 - 5.5e-92 307.3 0.1 6.7e-92 307.0 0.1 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase SecE PF00584.15 EAK90562.1 - 0.16 11.5 1.3 0.33 10.5 0.9 1.6 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Syntaxin-6_N PF09177.6 EAK90564.1 - 0.027 14.8 4.5 0.44 10.9 1.4 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal P4Ha_N PF08336.6 EAK90564.1 - 0.029 14.2 1.5 0.2 11.4 0.5 2.3 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Med4 PF10018.4 EAK90564.1 - 0.095 12.0 2.1 0.17 11.2 1.4 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF948 PF06103.6 EAK90564.1 - 0.097 12.5 2.2 0.67 9.8 0.7 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3573 PF12097.3 EAK90564.1 - 0.12 10.9 0.6 0.19 10.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3354 PF11834.3 EAK90564.1 - 0.18 11.4 3.2 4 7.1 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3354) DUF4164 PF13747.1 EAK90564.1 - 0.19 11.8 5.4 3.3 7.8 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.7 EAK90564.1 - 0.22 11.7 2.1 1.2 9.4 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Prp19 PF08606.6 EAK90564.1 - 1.7 8.4 5.0 1.6 8.4 0.7 2.5 2 1 0 2 2 2 0 Prp19/Pso4-like Transcrip_act PF04949.8 EAK90564.1 - 4.6 6.8 12.0 0.31 10.6 1.1 2.5 2 1 1 3 3 3 0 Transcriptional activator eIF2A PF08662.6 EAK90565.1 - 3.5e-53 180.1 0.0 6.9e-43 146.6 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EAK90565.1 - 0.0055 16.5 0.0 7.2 6.6 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Seipin PF06775.9 EAK90568.1 - 1.7e-11 43.9 0.8 3.3e-06 26.7 0.1 2.4 2 0 0 2 2 2 2 Putative adipose-regulatory protein (Seipin) PepSY_TM_3 PF13706.1 EAK90568.1 - 0.0059 16.0 1.4 0.0059 16.0 1.0 1.8 2 0 0 2 2 2 1 PepSY-associated TM helix SecY PF00344.15 EAK90569.1 - 6.3e-96 321.3 20.7 7.7e-96 321.0 14.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EAK90569.1 - 4.8e-19 67.5 0.1 2.2e-18 65.4 0.1 2.3 1 0 0 1 1 1 1 Plug domain of Sec61p RRM_1 PF00076.17 EAK90570.1 - 9.4e-17 60.4 0.0 1.4e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK90570.1 - 6.6e-16 58.0 0.0 1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK90570.1 - 1.7e-09 37.4 0.0 2.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAK90570.1 - 0.0016 18.1 0.0 0.0054 16.4 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif CDC45 PF02724.9 EAK90570.1 - 0.54 8.2 2.4 0.59 8.0 1.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DHQ_synthase PF01761.15 EAK90571.1 - 0.39 9.5 1.9 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 3-dehydroquinate synthase DivIC PF04977.10 EAK90571.1 - 1.6 8.2 16.0 0.052 13.0 1.0 3.4 3 0 0 3 3 3 0 Septum formation initiator TPR_12 PF13424.1 EAK90572.1 - 0.037 13.9 0.2 36 4.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Suf PF05843.9 EAK90572.1 - 0.5 10.0 25.4 1.3 8.6 0.0 4.7 4 1 0 4 4 4 0 Suppressor of forked protein (Suf) Ank_2 PF12796.2 EAK90573.1 - 2.4e-22 79.0 0.1 3.5e-16 59.3 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAK90573.1 - 4.6e-19 67.2 8.0 1.7e-05 24.4 0.0 6.4 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 EAK90573.1 - 2.1e-14 53.5 0.6 7.1e-07 29.5 0.0 6.0 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAK90573.1 - 2.2e-14 52.0 1.2 0.033 14.4 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EAK90573.1 - 3.1e-12 46.3 1.1 2.1e-05 24.5 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) 2OG-FeII_Oxy_2 PF13532.1 EAK90575.1 - 5.2e-19 68.8 0.1 3.3e-18 66.2 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EAK90575.1 - 1.9e-08 34.4 0.0 3.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3638 PF12340.3 EAK90576.1 - 4.5e-19 68.3 0.1 1.1e-17 63.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EAK90576.1 - 6.1e-16 57.2 0.3 1.1e-15 56.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_6 PF13405.1 EAK90576.1 - 3.1e-06 26.6 0.2 0.027 14.3 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EAK90576.1 - 2.2e-05 23.4 2.8 0.018 14.3 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.1 EAK90576.1 - 0.39 10.1 9.5 11 5.5 0.4 4.7 4 0 0 4 4 4 0 EF hand Atrophin-1 PF03154.10 EAK90576.1 - 3.5 5.6 0.3 6.3 4.8 0.2 1.3 1 0 0 1 1 1 0 Atrophin-1 family Trypan_PARP PF05887.6 EAK90576.1 - 9.5 6.0 0.8 29 4.4 0.6 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) G10 PF01125.12 EAK90577.1 - 5.8e-56 188.0 8.0 6.3e-56 187.9 5.5 1.0 1 0 0 1 1 1 1 G10 protein DUF4250 PF14056.1 EAK90577.1 - 0.11 12.2 0.6 0.26 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) DDE_Tnp_1 PF01609.16 EAK90577.1 - 0.99 8.9 4.4 0.8 9.1 0.1 2.0 1 1 1 2 2 2 0 Transposase DDE domain DUF2387 PF09526.5 EAK90577.1 - 6.8 6.6 12.2 1.4 8.9 0.2 2.6 2 1 0 3 3 3 0 Probable metal-binding protein (DUF2387) IBN_N PF03810.14 EAK90578.1 - 0.0096 15.8 0.3 0.021 14.7 0.2 1.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain RRP7 PF12923.2 EAK90579.1 - 0.0021 18.1 0.1 0.0021 18.1 0.1 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Zip PF02535.17 EAK90579.1 - 4.6 6.1 11.4 0.38 9.7 3.5 1.9 1 1 1 2 2 2 0 ZIP Zinc transporter JAB PF01398.16 EAK90580.1 - 1.5e-12 47.2 0.0 3.1e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EAK90580.1 - 0.00028 20.9 0.6 0.00054 20.0 0.2 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function DUF3121 PF11319.3 EAK90580.1 - 0.082 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) FPL PF09758.4 EAK90582.1 - 2.6e-32 111.6 12.4 2.6e-32 111.6 8.6 5.0 5 1 0 5 5 5 1 Uncharacterised conserved protein cwf21 PF08312.7 EAK90583.1 - 5.7e-07 29.2 7.8 1.9e-06 27.6 5.4 1.9 1 0 0 1 1 1 1 cwf21 domain Bromodomain PF00439.20 EAK90584.1 - 6.5e-22 77.2 1.8 1.5e-21 76.0 1.2 1.6 1 0 0 1 1 1 1 Bromodomain CDC45 PF02724.9 EAK90584.1 - 2 6.3 16.4 3.8 5.4 11.3 1.4 1 0 0 1 1 1 0 CDC45-like protein zf-RanBP PF00641.13 EAK90585.1 - 0.0014 17.6 4.3 0.0069 15.4 3.0 2.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Helicase_C PF00271.26 EAK90586.1 - 5.3e-11 42.2 0.7 1.6e-10 40.6 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.18 EAK90586.1 - 9e-11 41.7 0.0 9e-11 41.7 0.0 3.0 4 0 0 4 4 4 1 Helicase associated domain (HA2) DEAD PF00270.24 EAK90586.1 - 3.1e-07 30.0 0.9 7.2e-07 28.8 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EAK90586.1 - 0.0031 17.3 0.1 0.01 15.6 0.1 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold dsrm PF00035.20 EAK90586.1 - 0.0049 17.4 0.0 0.014 15.9 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif ABC_tran PF00005.22 EAK90586.1 - 0.017 15.4 3.1 0.024 14.9 0.0 2.9 3 0 0 3 3 3 0 ABC transporter T2SE PF00437.15 EAK90586.1 - 0.031 13.1 0.0 0.065 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DND1_DSRM PF14709.1 EAK90586.1 - 0.061 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.1 EAK90586.1 - 0.32 11.1 4.3 2.3 8.3 1.7 2.9 2 1 0 2 2 2 0 AAA domain Cir_N PF10197.4 EAK90587.1 - 1.7e-12 47.1 12.4 1.7e-12 47.1 8.6 2.2 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Slu7 PF11708.3 EAK90587.1 - 0.0038 17.0 11.1 0.0038 17.0 7.7 2.1 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor V_ATPase_I PF01496.14 EAK90587.1 - 0.86 7.3 9.4 0.072 10.9 3.7 1.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Pkinase PF00069.20 EAK90588.1 - 5.6e-29 101.0 0.1 1.8e-28 99.4 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK90588.1 - 8.5e-09 34.8 0.0 1.9e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Vps5 PF09325.5 EAK90590.1 - 0.014 14.6 2.2 0.021 14.0 1.5 1.2 1 0 0 1 1 1 0 Vps5 C terminal like NAS PF03059.11 EAK90590.1 - 0.02 14.0 3.1 0.026 13.6 2.2 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein Pox_VLTF3 PF04947.9 EAK90590.1 - 0.044 13.3 3.1 0.047 13.1 1.5 1.5 1 1 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Med11 PF10280.4 EAK90590.1 - 0.05 13.6 1.2 1.5 8.9 0.0 2.3 1 1 1 2 2 2 0 Mediator complex protein YMF19 PF02326.10 EAK90590.1 - 0.14 12.7 1.0 1.4 9.5 0.0 2.4 2 1 0 2 2 2 0 Plant ATP synthase F0 Mito_fiss_reg PF05308.6 EAK90590.1 - 0.41 9.9 9.1 0.76 9.1 6.3 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator IncA PF04156.9 EAK90590.1 - 0.59 9.7 9.9 1.6 8.3 7.0 1.5 1 1 0 1 1 1 0 IncA protein Cytokin_check_N PF10407.4 EAK90590.1 - 0.99 9.0 5.4 1 9.0 1.0 2.4 1 1 1 2 2 2 0 Cdc14 phosphatase binding protein N-terminus DUF4208 PF13907.1 EAK90590.1 - 3 8.1 6.2 13 6.0 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) YniB PF14002.1 EAK90593.1 - 0.033 13.6 0.0 0.073 12.5 0.0 1.6 1 0 0 1 1 1 0 YniB-like protein MAGP PF05507.6 EAK90593.1 - 0.044 13.5 0.7 0.082 12.7 0.5 1.4 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) VWA_N PF08399.6 EAK90593.1 - 0.9 10.1 5.6 0.44 11.1 2.2 1.7 2 0 0 2 2 2 0 VWA N-terminal Mucin PF01456.12 EAK90593.1 - 1.5 8.5 15.1 2.3 7.9 10.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Lactococcin PF04369.8 EAK90594.1 - 0.085 12.7 0.2 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Lactococcin-like family DUF1510 PF07423.6 EAK90596.1 - 0.32 10.3 26.0 0.026 13.9 3.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) PBP1_TM PF14812.1 EAK90596.1 - 4.7 7.5 9.3 23 5.3 0.1 2.7 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleo_P87 PF07267.6 EAK90596.1 - 4.8 5.7 12.2 6 5.4 8.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4058 PF13267.1 EAK90596.1 - 5.3 6.0 8.3 7.8 5.5 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) RNA_POL_M_15KD PF02150.11 EAK90597.1 - 9.4e-06 25.2 0.4 2e-05 24.1 0.3 1.5 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 EAK90597.1 - 0.037 13.8 0.2 0.055 13.2 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.17 EAK90597.1 - 0.063 13.0 1.2 0.096 12.4 0.8 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_4 PF15227.1 EAK90597.1 - 0.19 11.6 2.3 0.33 10.8 1.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-H2C2_2 PF13465.1 EAK90597.1 - 0.39 11.1 5.0 1.2 9.5 3.7 1.7 1 1 0 1 1 1 0 Zinc-finger double domain Glycos_transf_2 PF00535.21 EAK90598.1 - 9.1e-20 71.0 0.1 2e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 EAK90598.1 - 1.6e-11 43.7 0.0 1.6e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 EAK90598.1 - 5.7e-10 39.3 0.0 8.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.17 EAK90598.1 - 1.2e-06 28.5 0.1 2.8e-05 24.1 0.0 2.9 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 EAK90598.1 - 1.8e-06 27.3 0.2 4.7e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase GlcNAc PF11397.3 EAK90598.1 - 0.15 11.1 0.0 0.71 8.9 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase (GlcNAc) Ribosomal_S27e PF01667.12 EAK90599.1 - 9.9e-26 89.0 6.2 1.3e-25 88.6 4.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 Prok-RING_1 PF14446.1 EAK90599.1 - 0.019 14.6 2.9 0.03 14.0 2.0 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 IBR PF01485.16 EAK90599.1 - 0.02 14.7 2.8 0.026 14.4 1.9 1.3 1 0 0 1 1 1 0 IBR domain FYVE_2 PF02318.11 EAK90599.1 - 0.073 12.9 1.0 0.085 12.7 0.7 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger zf-ribbon_3 PF13248.1 EAK90599.1 - 0.2 10.9 3.8 0.69 9.2 2.4 2.0 1 1 1 2 2 2 0 zinc-ribbon domain zf-B_box PF00643.19 EAK90599.1 - 0.27 11.1 3.0 0.94 9.4 2.1 1.9 1 1 0 1 1 1 0 B-box zinc finger Zn_Tnp_IS1 PF03811.8 EAK90599.1 - 0.42 10.1 0.1 0.42 10.1 0.1 2.3 1 1 1 2 2 2 0 InsA N-terminal domain zf-DHHC PF01529.15 EAK90600.1 - 2.1e-37 128.2 14.3 2.1e-37 128.2 9.9 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase stn_TNFRSF12A PF12191.3 EAK90600.1 - 0.0077 16.2 0.7 0.014 15.4 0.5 1.5 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain RRM_1 PF00076.17 EAK90601.1 - 1.4e-17 63.0 0.1 2.3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK90601.1 - 2e-14 53.2 0.0 3.5e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAK90601.1 - 4.4e-14 52.0 1.2 1.5e-13 50.3 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAK90601.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF3882 PF07066.6 EAK90601.1 - 0.031 14.1 0.4 0.084 12.7 0.0 1.8 1 1 0 2 2 2 0 Lactococcus phage M3 protein DUF1542 PF07564.6 EAK90601.1 - 0.95 9.5 8.0 1.5 8.8 5.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Nol1_Nop2_Fmu PF01189.12 EAK90602.1 - 1.6e-30 106.4 0.0 9.8e-29 100.6 0.0 2.4 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 EAK90602.1 - 0.0097 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase SRP54 PF00448.17 EAK90603.1 - 3.1e-75 251.9 0.2 9.4e-75 250.3 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EAK90603.1 - 5.2e-30 103.7 4.7 5.2e-30 103.7 3.2 2.9 3 0 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.14 EAK90603.1 - 2.9e-15 56.1 1.0 7.3e-15 54.8 0.7 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 EAK90603.1 - 3.1e-07 30.3 0.0 6.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EAK90603.1 - 2.1e-06 27.4 0.0 6.2e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EAK90603.1 - 5.7e-06 25.8 0.1 4.7e-05 22.8 0.0 2.5 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.14 EAK90603.1 - 9e-06 25.2 0.2 5.2e-05 22.7 0.0 2.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_31 PF13614.1 EAK90603.1 - 9e-05 22.4 0.0 0.68 9.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EAK90603.1 - 0.0002 21.5 0.0 0.00072 19.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EAK90603.1 - 0.00022 20.1 0.6 0.011 14.5 0.0 3.2 2 1 1 3 3 3 1 ArgK protein AAA_17 PF13207.1 EAK90603.1 - 0.00039 21.2 0.0 0.00085 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EAK90603.1 - 0.00051 19.2 0.0 0.00096 18.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.15 EAK90603.1 - 0.0034 17.0 0.1 0.0095 15.6 0.0 1.8 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 EAK90603.1 - 0.0049 16.8 0.3 0.022 14.7 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain 6PF2K PF01591.13 EAK90603.1 - 0.008 15.2 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase ResIII PF04851.10 EAK90603.1 - 0.0082 15.9 0.0 0.043 13.6 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.12 EAK90603.1 - 0.0095 15.4 0.0 0.038 13.5 0.0 2.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EAK90603.1 - 0.015 15.5 0.0 0.059 13.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EAK90603.1 - 0.017 14.7 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EAK90603.1 - 0.029 13.7 0.1 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.1 EAK90603.1 - 0.033 14.1 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2209 PF09974.4 EAK90603.1 - 0.038 14.0 1.0 0.095 12.7 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) AAA PF00004.24 EAK90603.1 - 0.056 13.6 0.8 1.7 8.8 0.0 3.5 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EAK90603.1 - 0.064 12.6 0.0 0.62 9.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 EAK90603.1 - 0.077 12.1 0.0 0.25 10.4 0.0 1.9 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.1 EAK90603.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain CobN-Mg_chel PF02514.11 EAK90603.1 - 0.14 9.5 0.0 0.22 8.8 0.0 1.2 1 0 0 1 1 1 0 CobN/Magnesium Chelatase SRPRB PF09439.5 EAK90603.1 - 0.16 11.1 2.6 2.4 7.3 0.1 2.5 2 1 1 3 3 2 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 EAK90603.1 - 0.33 10.6 3.1 3.2 7.4 0.5 2.8 2 1 0 2 2 1 0 NTPase STOP PF05217.7 EAK90604.1 - 6.3e-15 55.4 13.5 1.2e-14 54.6 9.4 1.5 1 1 0 1 1 1 1 STOP protein Clr5 PF14420.1 EAK90604.1 - 0.00077 19.3 2.7 2.4 8.1 0.0 3.6 4 0 0 4 4 4 2 Clr5 domain IBN_N PF03810.14 EAK90605.1 - 3.1e-05 23.7 0.1 0.00013 21.7 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain GrpE PF01025.14 EAK90605.1 - 0.15 11.6 0.1 0.31 10.5 0.1 1.4 1 0 0 1 1 1 0 GrpE E1-E2_ATPase PF00122.15 EAK90606.1 - 3.8e-17 62.0 0.0 3.8e-17 62.0 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EAK90606.1 - 3.3e-16 60.3 0.0 1.1e-08 35.7 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAK90606.1 - 6.4e-15 55.8 0.0 1.9e-14 54.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAK90606.1 - 4.1e-06 26.6 0.0 1.5e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAK90606.1 - 0.0058 16.2 1.9 0.042 13.4 0.0 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EAK90606.1 - 0.086 12.7 0.0 0.37 10.7 0.0 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SMC_N PF02463.14 EAK90607.1 - 2.5e-61 206.7 52.8 9.4e-61 204.8 36.6 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EAK90607.1 - 4.7e-25 87.8 2.1 1.1e-24 86.6 0.0 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EAK90607.1 - 2.5e-16 60.5 9.7 4.8e-10 39.8 0.9 5.6 2 2 1 5 5 5 2 AAA domain AAA_23 PF13476.1 EAK90607.1 - 5.8e-15 56.1 9.8 5.8e-15 56.1 6.8 7.0 2 2 4 6 6 6 1 AAA domain AAA_29 PF13555.1 EAK90607.1 - 2.3e-07 30.2 0.0 4.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EAK90607.1 - 0.00032 19.3 13.7 0.00032 19.3 9.5 6.5 4 2 2 6 6 6 2 AAA domain Reo_sigmaC PF04582.7 EAK90607.1 - 0.0018 17.5 3.5 0.0018 17.5 2.4 5.5 2 2 4 6 6 6 4 Reovirus sigma C capsid protein TBPIP PF07106.8 EAK90607.1 - 0.005 16.4 10.0 0.005 16.4 7.0 9.0 2 2 6 9 9 9 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ribosomal_L44 PF00935.14 EAK90608.1 - 2.7e-31 107.4 14.8 3.4e-31 107.0 10.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 EAK90608.1 - 0.1 12.8 6.8 1.2 9.4 0.3 2.7 2 1 0 2 2 2 0 Ribosomal protein L33 Adaptin_N PF01602.15 EAK90609.1 - 5.4e-76 255.9 15.4 7.5e-76 255.5 10.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EAK90609.1 - 4.6e-33 114.1 0.2 1.9e-32 112.1 0.0 2.1 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EAK90609.1 - 5e-08 33.1 1.6 0.012 15.8 0.0 4.4 3 2 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 EAK90609.1 - 0.19 12.2 2.4 0.81 10.2 0.4 3.0 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 EAK90609.1 - 4.6 7.5 10.5 7.7 6.8 0.3 5.1 7 0 0 7 7 7 0 HEAT repeat Sld5 PF05916.6 EAK90610.1 - 1.8e-12 47.5 0.0 2.2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Glyco_hydro_15 PF00723.16 EAK90610.1 - 0.027 13.0 0.0 0.027 13.0 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 NPL4 PF05021.10 EAK90611.1 - 1.5e-69 234.5 0.0 2.2e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 NPL4 family UN_NPL4 PF11543.3 EAK90611.1 - 4.4e-21 74.9 0.5 1.3e-20 73.3 0.1 2.0 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 zf-NPL4 PF05020.10 EAK90611.1 - 2.8e-06 27.0 0.0 5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region ACP_syn_III_C PF08541.5 EAK90611.1 - 0.007 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ubiquitin PF00240.18 EAK90611.1 - 0.027 13.8 0.0 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Tubulin PF00091.20 EAK90612.1 - 2.4e-75 253.0 0.0 4.7e-75 252.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EAK90612.1 - 3.1e-44 150.0 0.9 3.1e-44 150.0 0.6 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EAK90612.1 - 0.00014 21.8 0.0 0.00057 19.9 0.0 2.0 2 1 0 2 2 2 1 Misato Segment II tubulin-like domain Hrs_helical PF12210.3 EAK90612.1 - 0.037 14.2 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Tubulin_2 PF13809.1 EAK90612.1 - 0.041 12.8 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Tubulin like SIR2 PF02146.12 EAK90613.1 - 2.9e-23 82.5 0.0 3.8e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF1936 PF09151.5 EAK90613.1 - 0.0051 16.2 0.1 0.0051 16.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1936) LSM PF01423.17 EAK90614.1 - 2.3e-14 52.6 0.1 3.1e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAK90614.1 - 2.7e-05 23.9 0.0 3.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Aha1_N PF09229.6 EAK90615.1 - 3.1e-36 124.2 19.5 1.6e-28 99.2 3.3 2.6 3 0 0 3 3 3 2 Activator of Hsp90 ATPase, N-terminal PRP21_like_P PF12230.3 EAK90616.1 - 2.2e-60 204.0 9.0 3.4e-60 203.4 6.2 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EAK90616.1 - 2.4e-32 110.3 0.3 1.4e-15 56.6 0.0 2.5 2 0 0 2 2 2 2 Surp module DUF3095 PF11294.3 EAK90617.1 - 0.25 10.3 3.8 0.63 9.0 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) DUF3782 PF12644.2 EAK90617.1 - 7.4 6.4 10.5 2e+02 1.8 4.7 4.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) ubiquitin PF00240.18 EAK90618.1 - 1.8e-35 120.1 0.5 2.3e-35 119.8 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EAK90618.1 - 2.4e-28 97.4 10.0 3.9e-28 96.7 6.9 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EAK90618.1 - 1.2e-20 72.9 0.4 1.9e-20 72.2 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EAK90618.1 - 1.5e-06 28.3 0.1 5.5e-06 26.5 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EAK90618.1 - 0.00029 20.5 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EAK90618.1 - 0.0041 16.9 0.1 0.0081 16.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EAK90618.1 - 0.023 14.8 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EAK90618.1 - 0.052 13.4 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG DUF2870 PF11069.3 EAK90618.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) eIF-5a PF01287.15 EAK90619.1 - 7.3e-24 83.5 0.0 1.1e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EAK90619.1 - 0.0036 16.9 0.1 0.0064 16.1 0.1 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EAK90619.1 - 0.056 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Arf PF00025.16 EAK90620.1 - 1.5e-62 209.8 0.0 1.8e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EAK90620.1 - 2.3e-12 46.2 0.8 4.9e-09 35.3 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EAK90620.1 - 4.4e-11 42.3 0.0 5.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EAK90620.1 - 1.9e-09 38.0 0.0 2.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EAK90620.1 - 2.3e-09 36.8 0.0 3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EAK90620.1 - 3e-07 30.3 0.0 4.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EAK90620.1 - 4.3e-06 26.0 0.0 4.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EAK90620.1 - 0.00039 19.9 0.0 0.011 15.2 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EAK90620.1 - 0.028 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNase_PH PF01138.16 EAK90621.1 - 1.8e-12 47.7 0.3 9.3e-12 45.4 0.0 2.2 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EAK90621.1 - 3.7e-09 36.3 0.0 8.5e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF2977 PF11192.3 EAK90621.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) Cpn10 PF00166.16 EAK90622.1 - 2.2e-15 56.3 0.0 3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit PS_pyruv_trans PF04230.8 EAK90623.1 - 4e-23 82.5 2.5 4e-23 82.5 1.7 1.5 2 0 0 2 2 2 1 Polysaccharide pyruvyl transferase SMC_N PF02463.14 EAK90624.1 - 3.6e-50 170.2 21.9 1.1e-49 168.6 15.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EAK90624.1 - 5.5e-30 103.8 0.3 1.6e-29 102.2 0.2 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EAK90624.1 - 5.3e-16 59.5 24.9 5.3e-16 59.5 17.2 7.4 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 EAK90624.1 - 6.6e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EAK90624.1 - 0.0055 16.9 0.0 0.0055 16.9 0.0 5.5 3 2 0 4 4 4 1 ABC transporter AAA_21 PF13304.1 EAK90624.1 - 0.39 10.6 87.7 0.013 15.4 10.6 6.4 2 2 1 3 3 3 0 AAA domain DUF501 PF04417.7 EAK90624.1 - 5.2 6.9 8.8 11 5.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF501) WD40 PF00400.27 EAK90625.1 - 0.0062 16.3 9.8 0.14 12.0 0.2 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat SLBP_RNA_bind PF15247.1 EAK90626.1 - 1.3e-20 72.9 1.0 2.3e-20 72.1 0.7 1.4 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain CTP_transf_2 PF01467.21 EAK90627.1 - 1.3e-19 70.8 0.0 6.8e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 EAK90627.1 - 0.00087 18.9 0.1 1.5 8.4 0.1 3.0 3 0 0 3 3 3 2 FAD synthetase DUF726 PF05277.7 EAK90627.1 - 0.0012 17.7 0.0 0.0088 14.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF726) TPP_enzyme_N PF02776.13 EAK90628.1 - 1e-35 122.7 0.0 2e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EAK90628.1 - 1.1e-21 76.9 0.0 2.5e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EAK90628.1 - 3.1e-16 59.3 0.0 1.3e-15 57.2 0.0 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 EAK90628.1 - 0.0071 15.9 0.2 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Phosducin PF02114.11 EAK90629.1 - 1.5e-08 33.7 2.0 1.6e-08 33.5 1.4 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EAK90629.1 - 3.9e-08 32.9 0.1 8.2e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Soyouz_module PF14313.1 EAK90629.1 - 0.41 10.2 2.4 1.3 8.6 0.6 2.5 3 0 0 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Cpn60_TCP1 PF00118.19 EAK90630.1 - 5.5e-143 477.1 7.0 6.3e-143 476.9 4.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-DHHC PF01529.15 EAK90631.1 - 5.9e-37 126.7 11.9 5.9e-37 126.7 8.3 2.4 1 1 1 2 2 2 1 DHHC palmitoyltransferase Orthopox_A36R PF05950.6 EAK90631.1 - 0.05 13.5 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Orthopoxvirus A36R protein Urm1 PF09138.6 EAK90632.1 - 3.9e-35 119.8 0.3 4.3e-35 119.7 0.2 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EAK90632.1 - 0.0078 16.6 0.1 0.025 15.0 0.1 1.9 1 1 0 1 1 1 1 ThiS family HHH_3 PF12836.2 EAK90632.1 - 0.14 12.1 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif Topoisom_I PF01028.15 EAK90633.1 - 7.1e-94 313.2 6.6 1.6e-93 312.1 4.6 1.6 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.10 EAK90633.1 - 4.3e-87 290.9 6.2 4.3e-87 290.9 4.3 3.3 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.1 EAK90633.1 - 2.5e-31 107.1 1.2 9.5e-31 105.2 0.8 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain KxDL PF10241.4 EAK90633.1 - 0.13 12.1 0.1 0.13 12.1 0.0 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein LSM PF01423.17 EAK90634.1 - 1.2e-11 44.0 0.3 1.5e-11 43.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain Gemin6 PF06372.7 EAK90634.1 - 0.11 11.7 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Gemin6 protein Rabaptin PF03528.10 EAK90635.1 - 0.012 15.4 13.5 0.2 11.5 2.1 2.4 2 0 0 2 2 2 0 Rabaptin DivIC PF04977.10 EAK90635.1 - 0.39 10.2 13.1 0.045 13.2 2.3 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 EAK90635.1 - 8.3 6.8 10.4 5.5 7.3 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Kelch_3 PF13415.1 EAK90636.1 - 1.1e-36 124.1 5.5 2.2e-07 30.8 0.0 7.0 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EAK90636.1 - 4.3e-33 112.8 10.9 1.1e-06 28.2 0.0 6.9 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EAK90636.1 - 1.9e-26 91.0 16.6 3.6e-07 30.0 0.1 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.1 EAK90636.1 - 6.5e-26 89.8 7.9 2.2e-06 27.5 0.0 6.4 6 0 0 6 6 6 6 Kelch motif DUF4110 PF13422.1 EAK90636.1 - 7.4e-19 67.3 0.7 7.4e-19 67.3 0.5 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.20 EAK90636.1 - 5.2e-18 64.3 24.1 7.9e-06 25.3 0.1 6.8 6 1 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EAK90636.1 - 6.3e-14 51.0 16.4 3.1e-05 23.5 0.4 6.6 6 0 0 6 6 6 5 Kelch motif Proteasome PF00227.21 EAK90637.1 - 3.3e-59 199.3 0.0 1.7e-58 197.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 EAK90637.1 - 2.1e-11 42.9 1.4 4.2e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DEAD PF00270.24 EAK90638.1 - 9.1e-39 132.6 0.1 2.6e-38 131.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAK90638.1 - 1.2e-27 95.5 0.1 2.4e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EAK90638.1 - 0.00068 18.7 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EAK90638.1 - 0.00097 18.8 0.0 0.025 14.3 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 EAK90638.1 - 0.0093 15.8 0.0 0.029 14.1 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EAK90638.1 - 0.016 14.7 0.0 0.05 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EAK90638.1 - 0.018 15.1 0.1 0.099 12.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EAK90638.1 - 0.059 12.8 0.0 0.064 12.7 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.1 EAK90638.1 - 0.16 11.5 0.2 1.2 8.6 0.0 2.2 3 0 0 3 3 3 0 AAA domain Ribosomal_L38e PF01781.13 EAK90639.1 - 1.3e-31 108.1 3.7 1.5e-31 107.9 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Thioredoxin PF00085.15 EAK90640.1 - 8.7e-53 176.3 0.1 2.8e-28 97.6 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EAK90640.1 - 4.5e-12 46.1 0.2 2.1e-06 27.7 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EAK90640.1 - 6.5e-11 42.2 0.3 4e-05 23.6 0.0 3.9 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EAK90640.1 - 7.5e-09 35.5 0.0 0.0059 16.6 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EAK90640.1 - 1.3e-08 34.9 5.8 0.0036 17.4 0.1 4.9 4 2 0 4 4 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EAK90640.1 - 1.6e-05 24.6 0.1 0.01 15.5 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_3 PF13192.1 EAK90640.1 - 0.00033 20.3 0.0 0.013 15.3 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain Redoxin PF08534.5 EAK90640.1 - 0.00062 19.3 0.1 0.096 12.2 0.1 2.6 3 0 0 3 3 3 1 Redoxin Thioredoxin_4 PF13462.1 EAK90640.1 - 0.00067 19.6 1.2 0.028 14.4 0.1 3.0 2 2 1 3 3 3 1 Thioredoxin Thioredoxin_9 PF14595.1 EAK90640.1 - 0.0013 18.2 0.0 1.4 8.5 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin DSBA PF01323.15 EAK90640.1 - 0.032 13.7 0.4 1.7 8.1 0.0 3.1 2 2 1 3 3 3 0 DSBA-like thioredoxin domain DDE_Tnp_1_2 PF13586.1 EAK90640.1 - 0.13 12.4 0.0 15 5.8 0.0 2.7 2 1 0 2 2 2 0 Transposase DDE domain Nol1_Nop2_Fmu PF01189.12 EAK90641.1 - 7.2e-15 55.1 0.0 1.1e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EAK90641.1 - 0.0022 17.6 0.1 0.61 9.6 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Band_7 PF01145.20 EAK90642.1 - 9.4e-26 90.8 0.3 1.7e-25 89.9 0.2 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.3 EAK90642.1 - 4.7e-05 22.4 0.6 6.6e-05 21.9 0.4 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Nudc_N PF14050.1 EAK90643.1 - 3.2e-19 68.6 1.6 9.7e-19 67.0 1.1 1.9 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.11 EAK90643.1 - 1.1e-16 61.1 1.8 2e-16 60.3 1.3 1.5 1 0 0 1 1 1 1 CS domain DUF1682 PF07946.9 EAK90643.1 - 0.059 12.2 8.9 0.034 13.0 4.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Metal_resist PF13801.1 EAK90643.1 - 0.65 9.9 4.2 12 5.9 0.6 2.2 2 0 0 2 2 2 0 Heavy-metal resistance LSM PF01423.17 EAK90645.1 - 1.7e-16 59.5 0.4 2.3e-16 59.0 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAK90645.1 - 0.0019 18.1 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Rep_fac-A_C PF08646.5 EAK90646.1 - 4e-46 156.3 0.8 3.1e-45 153.4 0.1 2.2 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 EAK90646.1 - 2.4e-15 56.1 0.3 1e-11 44.5 0.2 3.9 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 EAK90646.1 - 1.4e-07 31.4 0.2 4.2e-06 26.7 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF223 Sgf11 PF08209.6 EAK90646.1 - 0.14 11.4 2.5 2.2 7.6 0.1 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) PP2C PF00481.16 EAK90647.1 - 2.6e-13 49.9 0.6 7.3e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EAK90647.1 - 5.3e-12 45.8 0.0 1.9e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EAK90647.1 - 1.4e-08 34.4 0.0 2.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C XPC-binding PF09280.6 EAK90648.1 - 1.6e-23 81.8 4.9 4.2e-23 80.5 3.4 1.7 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 EAK90648.1 - 2.5e-23 81.2 1.8 1.3e-11 43.9 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 EAK90648.1 - 1.5e-15 56.3 0.1 3.3e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EAK90648.1 - 1.1e-09 37.8 0.7 1.9e-09 37.0 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EAK90648.1 - 6.9e-07 29.3 1.6 2.4e-06 27.6 0.3 2.2 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EAK90648.1 - 8.4e-07 28.8 1.4 1.8e-06 27.8 1.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 EAK90648.1 - 1.7e-05 24.3 0.0 0.082 12.5 0.0 2.9 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain YukD PF08817.5 EAK90648.1 - 0.0021 18.5 0.0 0.0043 17.5 0.0 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Rap1_C PF11626.3 EAK90648.1 - 0.01 15.6 0.0 4.8 7.1 0.0 2.7 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3306 PF11748.3 EAK90648.1 - 0.033 14.8 0.9 0.1 13.2 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DnaB_2 PF07261.6 EAK90648.1 - 0.27 10.8 3.6 4.1 7.0 0.0 3.6 4 1 1 5 5 5 0 Replication initiation and membrane attachment KH_1 PF00013.24 EAK90648.1 - 1.8 8.2 4.7 2 8.1 2.3 1.9 2 0 0 2 2 2 0 KH domain Ashwin PF15323.1 EAK90648.1 - 4.9 7.0 14.4 4.5 7.2 2.1 2.3 2 0 0 2 2 2 0 Developmental protein Aa_trans PF01490.13 EAK90649.1 - 1.1e-49 169.0 30.0 4.9e-49 166.9 20.8 1.7 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Unstab_antitox PF09720.5 EAK90649.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative addiction module component Coatomer_WDAD PF04053.9 EAK90650.1 - 9.3e-127 423.4 2.2 1.8e-126 422.4 0.1 2.1 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EAK90650.1 - 3.3e-50 166.2 18.9 8.8e-14 50.7 0.0 8.7 9 0 0 9 9 9 6 WD domain, G-beta repeat Nup160 PF11715.3 EAK90650.1 - 2.1e-05 22.8 0.2 0.007 14.5 0.0 2.5 2 0 0 2 2 2 2 Nucleoporin Nup120/160 TPR_8 PF13181.1 EAK90650.1 - 0.0011 18.6 0.1 0.011 15.4 0.0 2.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAK90650.1 - 0.0033 16.9 0.0 0.018 14.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAK90650.1 - 0.011 15.5 0.0 0.069 13.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat CNH PF00780.17 EAK90650.1 - 0.013 14.9 0.2 0.22 10.9 0.0 2.5 3 0 0 3 3 3 0 CNH domain ATP-synt_ab PF00006.20 EAK90651.1 - 1e-107 358.5 0.0 1.5e-107 358.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EAK90651.1 - 2.3e-22 79.5 1.6 4.2e-22 78.7 1.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EAK90651.1 - 5.3e-14 52.1 2.0 6e-14 52.0 0.5 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 EAK90651.1 - 0.036 13.9 0.0 0.092 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ribosomal_S10 PF00338.17 EAK90652.1 - 3.2e-31 107.0 0.3 5.2e-31 106.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF59 PF01883.14 EAK90653.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function DUF59 NAC PF01849.13 EAK90653.1 - 0.027 13.9 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 NAC domain SET PF00856.23 EAK90654.1 - 5.9e-21 75.4 0.3 1.2e-20 74.4 0.2 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EAK90654.1 - 0.0034 17.2 13.4 0.0034 17.2 9.3 3.5 3 1 0 3 3 3 1 MYND finger DUF1073 PF06381.6 EAK90654.1 - 0.013 14.0 0.3 0.044 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1073) EAP30 PF04157.11 EAK90654.1 - 0.08 12.0 0.9 0.2 10.8 0.5 1.8 2 0 0 2 2 2 0 EAP30/Vps36 family RRM_5 PF13893.1 EAK90655.1 - 4.3e-12 45.7 0.0 8.2e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAK90655.1 - 6.4e-08 32.1 0.1 1.4e-07 31.0 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAK90655.1 - 3.9e-05 23.5 0.0 7.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Tyr_Deacylase PF02580.11 EAK90656.1 - 1.8e-41 141.5 0.0 2.1e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Methyltransf_16 PF10294.4 EAK90657.1 - 7.8e-22 77.5 0.2 1.6e-21 76.5 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Ank_2 PF12796.2 EAK90657.1 - 1.2e-17 63.9 0.9 7.8e-17 61.3 0.2 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAK90657.1 - 4.8e-17 61.9 1.6 2.2e-08 34.3 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAK90657.1 - 7.6e-17 60.9 1.6 2.5e-12 46.6 0.6 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EAK90657.1 - 4.1e-15 54.7 0.9 2.9e-09 36.2 0.3 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EAK90657.1 - 1.2e-12 46.7 1.2 1.3e-05 24.9 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat Methyltransf_18 PF12847.2 EAK90657.1 - 0.00019 22.0 0.0 0.00051 20.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAK90657.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAK90657.1 - 0.0018 17.6 0.0 0.0045 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EAK90657.1 - 0.0024 17.4 0.0 0.0072 15.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAK90657.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EAK90657.1 - 0.064 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EAK90657.1 - 0.065 13.7 0.2 0.24 11.8 0.0 2.1 2 1 0 2 2 1 0 Methyltransferase domain EIF_2_alpha PF07541.7 EAK90658.1 - 7.4e-34 115.8 0.3 3.5e-32 110.4 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EAK90658.1 - 9.8e-13 48.0 0.6 2.1e-12 46.9 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 EAK90658.1 - 0.4 10.6 3.6 0.47 10.4 0.0 2.7 2 2 0 2 2 2 0 Exosome component EXOSC1/CSL4 Ribosomal_L24e PF01246.15 EAK90659.1 - 2.7e-28 97.5 5.2 7.4e-28 96.2 3.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 EAK90659.1 - 0.001 18.6 2.9 0.0026 17.3 2.0 1.7 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif zf-PHD-like PF15446.1 EAK90659.1 - 0.02 14.1 0.7 0.053 12.8 0.5 1.6 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain FDF PF09532.5 EAK90659.1 - 0.021 15.3 2.6 0.04 14.4 1.8 1.5 1 0 0 1 1 1 0 FDF domain LSM PF01423.17 EAK90660.1 - 1.8e-13 49.8 2.1 2.3e-13 49.4 1.4 1.2 1 0 0 1 1 1 1 LSM domain s48_45 PF07422.8 EAK90660.1 - 0.056 13.5 0.2 0.066 13.3 0.1 1.3 1 0 0 1 1 1 0 Sexual stage antigen s48/45 domain LSM14 PF12701.2 EAK90660.1 - 0.089 12.6 0.3 0.1 12.4 0.2 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain Gemin6 PF06372.7 EAK90660.1 - 0.096 11.9 0.2 0.1 11.9 0.1 1.3 1 1 0 1 1 1 0 Gemin6 protein Peptidase_M23 PF01551.17 EAK90660.1 - 0.1 12.6 0.1 0.22 11.6 0.0 1.6 1 1 1 2 2 2 0 Peptidase family M23 Sarcolipin PF05366.6 EAK90660.1 - 0.16 11.3 0.4 0.28 10.6 0.3 1.3 1 0 0 1 1 1 0 Sarcolipin Prp18 PF02840.10 EAK90661.1 - 2.8e-56 189.3 0.3 2.8e-56 189.3 0.2 1.7 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EAK90661.1 - 1.5e-14 52.8 2.8 3.2e-14 51.8 2.0 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like DUF3523 PF12037.3 EAK90661.1 - 1.3 7.9 10.4 0.044 12.7 3.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) Pkinase PF00069.20 EAK90662.1 - 3e-65 219.9 0.2 7.8e-64 215.3 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAK90662.1 - 2.7e-34 118.4 0.0 4.2e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 EAK90662.1 - 3.6e-12 46.2 0.2 4e-07 30.0 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EAK90662.1 - 2.6e-09 35.7 0.6 0.015 14.5 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EAK90662.1 - 2.5e-08 33.1 0.5 0.026 14.3 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EAK90662.1 - 5.6e-08 32.2 1.0 0.0016 18.0 0.0 3.5 1 1 2 3 3 3 2 EF-hand domain pair Kdo PF06293.9 EAK90662.1 - 2.5e-05 23.4 0.0 0.00028 20.0 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAK90662.1 - 0.00017 20.6 0.0 0.00028 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like EF-hand_5 PF13202.1 EAK90662.1 - 0.001 18.3 1.6 0.71 9.3 0.1 2.7 2 0 0 2 2 2 2 EF hand APH PF01636.18 EAK90662.1 - 0.0044 16.7 0.0 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EAK90662.1 - 0.044 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Ecdysteroid kinase zf-C3HC4_3 PF13920.1 EAK90663.1 - 3.1e-06 26.7 11.3 3.1e-06 26.7 7.8 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAK90663.1 - 4.9e-06 26.3 8.0 4.9e-06 26.3 5.6 4.9 5 0 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EAK90663.1 - 6.8e-06 25.6 9.8 6.8e-06 25.6 6.8 4.8 2 2 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAK90663.1 - 2.5e-05 23.8 13.6 2.5e-05 23.8 9.4 4.1 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAK90663.1 - 0.00012 21.9 14.2 0.00012 21.9 9.8 4.2 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAK90663.1 - 0.00051 19.8 15.2 0.00051 19.8 10.5 4.0 3 2 0 3 3 3 1 Ring finger domain Rubredoxin PF00301.15 EAK90663.1 - 0.0006 19.6 5.2 0.24 11.3 0.0 4.6 4 0 0 4 4 4 1 Rubredoxin U-box PF04564.10 EAK90663.1 - 0.0036 17.2 1.3 0.46 10.4 0.2 2.6 2 0 0 2 2 2 1 U-box domain Ribosomal_S11 PF00411.14 EAK90664.1 - 4.5e-40 136.2 0.7 5.3e-40 136.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 EAK90664.1 - 0.046 13.5 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF814) Dynamitin PF04912.9 EAK90666.1 - 5.1e-06 25.5 0.3 5.8e-06 25.3 0.2 1.1 1 0 0 1 1 1 1 Dynamitin PerC PF06069.6 EAK90666.1 - 0.083 12.9 0.0 4.1 7.5 0.0 2.1 1 1 1 2 2 2 0 PerC transcriptional activator VIT1 PF01988.14 EAK90667.1 - 3.3e-57 193.4 0.7 4e-57 193.1 0.5 1.1 1 0 0 1 1 1 1 VIT family DUF1129 PF06570.6 EAK90667.1 - 0.04 13.2 1.6 1.2 8.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) VMA21 PF09446.5 EAK90667.1 - 0.044 13.6 0.7 0.044 13.6 0.5 2.1 2 0 0 2 2 2 0 VMA21-like domain Mig-14 PF07395.6 EAK90667.1 - 0.11 11.4 0.1 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Mig-14 EMP70 PF02990.11 EAK90668.1 - 5.9e-89 298.9 26.1 9.1e-89 298.2 18.1 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 GBV-C_env PF12786.2 EAK90668.1 - 0.2 10.0 0.5 0.32 9.4 0.3 1.2 1 0 0 1 1 1 0 GB virus C genotype envelope RIO1 PF01163.17 EAK90669.1 - 6e-45 152.9 0.1 3.5e-44 150.4 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.6 EAK90669.1 - 5e-32 109.8 0.4 1.3e-31 108.5 0.3 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EAK90669.1 - 0.00016 21.4 0.2 0.0079 15.9 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EAK90669.1 - 0.0029 16.7 0.1 0.021 13.9 0.1 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Daxx PF03344.10 EAK90669.1 - 0.0073 14.8 28.7 0.0095 14.4 19.9 1.1 1 0 0 1 1 1 1 Daxx Family RR_TM4-6 PF06459.7 EAK90669.1 - 0.045 13.6 14.2 0.069 13.0 9.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CENP-T PF15511.1 EAK90669.1 - 0.057 12.6 14.1 0.074 12.2 9.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TrmB PF01978.14 EAK90669.1 - 0.064 12.9 0.4 0.4 10.4 0.1 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB PPP4R2 PF09184.6 EAK90669.1 - 0.077 12.5 27.0 0.13 11.7 18.7 1.3 1 0 0 1 1 1 0 PPP4R2 Ycf1 PF05758.7 EAK90669.1 - 0.1 10.3 16.8 0.14 9.8 11.6 1.2 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 EAK90669.1 - 0.19 9.6 33.7 0.27 9.0 23.4 1.2 1 0 0 1 1 1 0 Nop14-like family Astro_capsid PF03115.9 EAK90669.1 - 0.48 8.6 11.1 0.59 8.3 7.7 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Upf2 PF04050.9 EAK90669.1 - 0.66 9.7 29.0 0.97 9.1 20.1 1.3 1 0 0 1 1 1 0 Up-frameshift suppressor 2 CDC45 PF02724.9 EAK90669.1 - 0.67 7.9 25.4 1 7.3 17.6 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 EAK90669.1 - 1.2 7.7 32.4 2 7.0 22.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.6 EAK90669.1 - 2.1 6.3 19.3 3.3 5.6 13.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.7 EAK90669.1 - 2.6 7.0 29.6 4.4 6.3 20.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ldh_1_N PF00056.18 EAK90670.1 - 3.1e-42 143.7 0.3 1e-41 142.0 0.1 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EAK90670.1 - 5.5e-35 120.6 0.1 8.4e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.12 EAK90670.1 - 9.5e-05 22.7 0.3 0.00084 19.7 0.0 2.5 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 EAK90670.1 - 0.00033 20.0 1.3 0.0065 15.8 0.4 2.8 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EAK90670.1 - 0.0039 16.9 0.0 0.0082 15.8 0.0 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glyco_hydro_4 PF02056.11 EAK90670.1 - 0.0083 15.4 1.6 0.022 14.0 0.1 2.3 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase Shikimate_DH PF01488.15 EAK90670.1 - 0.053 13.6 0.9 0.8 9.8 0.2 2.8 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EAK90670.1 - 0.09 12.4 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EAK90670.1 - 0.11 11.6 0.0 0.29 10.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 EAK90671.1 - 2e-35 121.6 0.2 3.2e-35 120.9 0.2 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EAK90671.1 - 3.3e-30 105.1 0.0 4.8e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 EAK90671.1 - 0.0015 17.8 0.1 0.0057 15.9 0.0 2.0 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase 3HCDH_N PF02737.13 EAK90671.1 - 0.0064 16.1 0.4 0.016 14.8 0.2 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EAK90671.1 - 0.0075 15.6 1.0 0.028 13.7 0.7 2.0 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EAK90671.1 - 0.014 15.1 0.1 0.034 13.8 0.1 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TFIIS_C PF01096.13 EAK90672.1 - 6.3e-21 73.7 2.6 6.3e-21 73.7 1.8 1.5 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) DUF2387 PF09526.5 EAK90672.1 - 0.00088 19.1 0.2 0.0011 18.8 0.2 1.1 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.2 EAK90672.1 - 0.0024 17.6 0.4 0.0037 17.0 0.2 1.4 1 1 0 1 1 1 1 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.3 EAK90672.1 - 0.0093 15.3 1.0 0.035 13.4 0.0 1.9 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain C1_2 PF03107.11 EAK90672.1 - 0.019 15.0 6.1 0.66 10.1 0.2 2.5 2 1 0 2 2 2 0 C1 domain PhnA_Zn_Ribbon PF08274.7 EAK90672.1 - 0.12 12.2 0.2 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon C1_3 PF07649.7 EAK90672.1 - 0.16 12.0 0.2 0.16 12.0 0.2 2.6 3 0 0 3 3 3 0 C1-like domain DUF2082 PF09855.4 EAK90672.1 - 1.6 8.6 5.1 2.6 7.9 0.3 2.3 2 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-H2C2_2 PF13465.1 EAK90672.1 - 1.6 9.1 3.8 19 5.7 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger double domain A2L_zn_ribbon PF08792.5 EAK90672.1 - 2.3 7.7 5.2 1 8.8 0.4 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Prefoldin_2 PF01920.15 EAK90673.1 - 2.1e-08 33.8 0.9 2.4e-08 33.6 0.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit YojJ PF10372.4 EAK90673.1 - 0.0082 15.9 0.4 0.0082 15.9 0.3 1.5 2 0 0 2 2 2 1 Bacterial membrane-spanning protein N-terminus Syntaxin PF00804.20 EAK90673.1 - 0.0085 16.2 0.0 0.0085 16.2 0.0 1.1 1 0 0 1 1 1 1 Syntaxin Transcrip_act PF04949.8 EAK90673.1 - 0.023 14.3 0.8 0.029 14.0 0.6 1.1 1 0 0 1 1 1 0 Transcriptional activator DUF1319 PF07028.6 EAK90673.1 - 0.026 14.7 0.1 0.027 14.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) DUF883 PF05957.8 EAK90673.1 - 0.037 14.4 0.2 0.046 14.1 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) KfrA_N PF11740.3 EAK90673.1 - 0.047 14.1 0.0 0.054 13.9 0.0 1.0 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF869 PF05911.6 EAK90673.1 - 0.049 11.8 1.4 0.059 11.6 1.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) HSCB_C PF07743.8 EAK90673.1 - 0.063 13.7 1.9 0.12 12.8 1.3 1.6 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain ACCA PF03255.9 EAK90673.1 - 0.074 12.6 0.4 0.091 12.3 0.3 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FlgM PF04316.8 EAK90673.1 - 0.074 13.0 0.1 0.79 9.7 0.0 2.0 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DUF4200 PF13863.1 EAK90673.1 - 0.08 12.8 3.7 0.1 12.5 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) EMP24_GP25L PF01105.19 EAK90673.1 - 0.1 12.3 0.2 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ZapA PF05164.8 EAK90673.1 - 0.14 12.1 0.7 0.17 11.8 0.5 1.1 1 0 0 1 1 1 0 Cell division protein ZapA Osmo_CC PF08946.5 EAK90673.1 - 0.99 9.4 4.9 1.3 9.0 3.4 1.2 1 0 0 1 1 1 0 Osmosensory transporter coiled coil LSM PF01423.17 EAK90674.1 - 4.5e-19 67.7 0.1 5.6e-19 67.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain Metallophos PF00149.23 EAK90676.1 - 2.6e-41 141.2 0.5 3.4e-41 140.8 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAK90676.1 - 0.031 14.1 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CBM_X PF06204.6 EAK90676.1 - 0.3 10.5 1.1 0.7 9.4 0.1 2.0 2 0 0 2 2 2 0 Putative carbohydrate binding domain PGK PF00162.14 EAK90677.1 - 1.4e-146 488.0 0.5 1.5e-146 487.8 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase NARP1 PF12569.3 EAK90678.1 - 5.2e-49 167.3 23.0 5.7e-42 144.1 9.2 3.2 3 0 0 3 3 3 3 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EAK90678.1 - 6.4e-10 38.5 0.6 1e-05 25.0 0.2 5.6 4 1 2 6 6 6 3 TPR repeat TPR_2 PF07719.12 EAK90678.1 - 8.6e-10 37.7 10.9 0.00028 20.5 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAK90678.1 - 7.2e-07 29.4 2.6 0.081 13.2 0.0 5.1 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAK90678.1 - 2.4e-05 24.1 5.4 0.027 14.6 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAK90678.1 - 8.7e-05 21.9 14.3 0.00065 19.1 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAK90678.1 - 0.00014 22.1 0.0 3.6 8.4 0.0 5.6 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAK90678.1 - 0.00019 21.3 7.3 0.01 15.7 0.0 5.1 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAK90678.1 - 0.0023 17.6 1.2 0.25 11.2 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAK90678.1 - 0.039 14.6 0.0 1.7e+02 3.0 0.0 5.3 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAK90678.1 - 0.091 13.2 0.1 93 3.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EAK90678.1 - 0.15 11.8 0.0 0.15 11.8 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat S4 PF01479.20 EAK90679.1 - 7.4e-09 34.9 0.0 1.4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain LSM PF01423.17 EAK90680.1 - 8.5e-13 47.6 2.2 1.4e-12 47.0 1.5 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAK90680.1 - 0.086 12.7 0.1 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF3352 PF11832.3 EAK90681.1 - 9e-30 103.4 0.0 9.1e-21 73.7 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3352) zf-CCCH PF00642.19 EAK90681.1 - 4.2e-16 58.2 11.1 3.3e-07 29.8 0.5 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EAK90681.1 - 6.9e-06 25.8 6.7 0.022 14.7 0.7 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type Pkinase PF00069.20 EAK90682.1 - 4.9e-54 183.2 0.2 3.9e-35 121.2 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAK90682.1 - 9.4e-33 113.3 0.0 5e-23 81.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_7 PF13499.1 EAK90682.1 - 2.1e-30 104.6 2.4 2.7e-11 43.4 0.2 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 EAK90682.1 - 4.4e-28 94.4 15.2 9.1e-06 24.6 0.1 5.9 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.1 EAK90682.1 - 4.8e-24 82.0 9.4 4.2e-05 23.0 0.1 5.8 5 0 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.1 EAK90682.1 - 2.1e-23 80.5 13.4 2.2e-05 23.5 0.9 5.7 5 0 0 5 5 5 5 EF hand EF-hand_8 PF13833.1 EAK90682.1 - 1.8e-20 72.2 10.5 9.7e-05 21.9 0.2 5.7 4 1 1 5 5 5 5 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EAK90682.1 - 6.3e-06 26.1 2.0 0.077 13.0 0.0 4.4 4 0 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.1 EAK90682.1 - 2.4e-05 23.4 0.0 0.063 12.2 0.0 2.9 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 EAK90682.1 - 0.0023 17.0 0.2 0.0095 15.0 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.2 EAK90682.1 - 0.11 12.2 4.7 1.8 8.3 0.0 3.5 2 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand CTP_transf_2 PF01467.21 EAK90683.1 - 0.027 14.5 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase Peptidase_M16 PF00675.15 EAZ51200.1 - 7e-26 90.7 0.0 1.8e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAZ51200.1 - 1e-08 35.0 1.0 1e-08 35.0 0.7 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Pkinase PF00069.20 EAZ51201.1 - 9.3e-40 136.4 0.0 1.8e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51201.1 - 1.6e-19 70.0 0.0 2.3e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAZ51201.1 - 0.0005 19.8 0.0 0.00099 18.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EAZ51201.1 - 0.0087 14.9 0.9 0.015 14.1 0.0 1.7 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EAZ51201.1 - 0.028 13.4 0.0 1.6 7.6 0.0 2.5 2 1 0 2 2 2 0 Kinase-like Kdo PF06293.9 EAZ51201.1 - 0.028 13.4 0.0 0.053 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family cEGF PF12662.2 EAZ51202.1 - 1.4e-05 24.6 5.1 1.4e-05 24.6 3.5 2.1 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_3 PF12947.2 EAZ51202.1 - 0.00013 21.8 7.5 0.00013 21.8 5.2 2.7 2 0 0 2 2 2 1 EGF domain EGF_CA PF07645.10 EAZ51202.1 - 0.0028 17.6 10.6 0.0028 17.6 7.4 2.9 3 0 0 3 3 3 2 Calcium-binding EGF domain Metallophos PF00149.23 EAZ51203.1 - 6.6e-38 130.1 1.4 1e-37 129.5 0.5 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Kelch_5 PF13854.1 EAZ51203.1 - 2.6e-11 43.2 0.2 0.00014 21.7 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EAZ51203.1 - 1.6e-10 40.5 4.3 0.0002 21.0 0.0 4.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EAZ51203.1 - 2.7e-07 30.0 0.7 0.00048 19.7 0.0 3.4 2 1 1 3 3 3 2 Kelch motif Kelch_3 PF13415.1 EAZ51203.1 - 3.2e-07 30.3 9.3 8.3e-07 29.0 0.0 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EAZ51203.1 - 2.4e-06 27.4 0.3 0.052 13.7 0.0 3.7 2 1 1 3 3 3 2 Kelch motif Kelch_1 PF01344.20 EAZ51203.1 - 4e-06 26.2 0.5 0.0047 16.4 0.0 3.3 2 1 0 2 2 2 2 Kelch motif Pkinase PF00069.20 EAZ51204.1 - 6.3e-68 228.7 0.0 2.4e-34 118.6 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51204.1 - 2.1e-27 95.8 0.0 1.2e-15 57.3 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_6 PF13405.1 EAZ51204.1 - 6.1e-12 44.3 1.0 0.013 15.3 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 EAZ51204.1 - 1e-08 33.8 0.7 0.0017 17.5 0.1 4.1 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 EAZ51204.1 - 3.3e-08 33.5 3.7 0.0033 17.5 0.3 5.1 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EAZ51204.1 - 4.9e-06 25.6 1.8 0.0052 16.0 0.2 3.0 3 0 0 3 3 3 2 EF hand Kdo PF06293.9 EAZ51204.1 - 0.036 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_8 PF13833.1 EAZ51204.1 - 0.32 10.6 4.5 11 5.7 0.1 3.9 4 1 1 5 5 5 0 EF-hand domain pair Synaptobrevin PF00957.16 EAZ51205.1 - 1.5e-20 72.5 1.3 2.5e-20 71.8 0.9 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EAZ51205.1 - 7.8e-13 47.7 0.1 1.7e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain TatD_DNase PF01026.16 EAZ51206.1 - 2.1e-35 122.1 0.0 2.9e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Adaptin_N PF01602.15 EAZ51207.1 - 5.8e-59 199.8 26.5 1.5e-49 168.7 12.0 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EAZ51207.1 - 5.4e-36 123.1 4.3 2.4e-17 62.8 0.4 3.5 2 1 0 2 2 2 2 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EAZ51207.1 - 5.6e-26 90.8 2.4 1.5e-25 89.4 0.9 2.2 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EAZ51207.1 - 1.1e-06 28.7 0.0 0.00051 20.2 0.0 3.5 4 1 1 5 5 5 1 HEAT repeats HEAT PF02985.17 EAZ51207.1 - 5.9e-05 22.8 0.1 0.043 13.9 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat DUF2435 PF10363.4 EAZ51207.1 - 2.8 7.9 6.7 0.69 9.8 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) ABC_tran PF00005.22 EAZ51210.1 - 6.6e-32 110.6 0.2 1.2e-20 74.2 0.0 3.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAZ51210.1 - 3.6e-12 46.2 12.7 3.6e-12 46.2 8.8 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EAZ51210.1 - 4.8e-07 29.2 4.1 0.0075 15.5 0.3 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EAZ51210.1 - 1e-06 28.6 0.5 0.017 15.0 0.6 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EAZ51210.1 - 1e-05 24.9 0.4 0.03 13.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EAZ51210.1 - 1.2e-05 24.6 0.3 0.014 14.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EAZ51210.1 - 0.00015 22.5 0.1 0.37 11.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EAZ51210.1 - 0.0002 21.8 0.2 0.24 11.8 0.1 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 EAZ51210.1 - 0.00031 20.7 1.5 0.028 14.3 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain T2SE PF00437.15 EAZ51210.1 - 0.00033 19.6 0.2 0.028 13.3 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.14 EAZ51210.1 - 0.0024 17.3 0.8 0.7 9.3 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EAZ51210.1 - 0.0029 17.3 1.8 1.3 8.7 0.3 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EAZ51210.1 - 0.0029 17.9 4.0 1.9 8.7 0.4 3.6 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EAZ51210.1 - 0.0035 17.4 0.6 0.57 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EAZ51210.1 - 0.0039 16.7 1.9 1.3 8.4 0.0 3.2 4 0 0 4 4 3 1 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.4 EAZ51210.1 - 0.0046 16.4 0.2 3.4 7.1 0.1 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EAZ51210.1 - 0.0072 16.0 0.3 3 7.4 0.0 3.3 2 1 1 3 3 3 1 Archaeal ATPase Dynamin_N PF00350.18 EAZ51210.1 - 0.0091 15.8 1.9 1.1 9.1 0.1 2.8 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.1 EAZ51210.1 - 0.016 14.6 0.1 1 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EAZ51210.1 - 0.043 13.6 0.1 7.3 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EAZ51210.1 - 0.049 13.3 1.2 12 5.5 0.4 2.9 3 0 0 3 3 2 0 NTPase RNA_helicase PF00910.17 EAZ51210.1 - 0.074 13.2 2.8 5.4 7.2 0.0 3.5 3 0 0 3 3 3 0 RNA helicase AAA_28 PF13521.1 EAZ51210.1 - 0.08 12.8 0.6 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EAZ51210.1 - 0.1 11.7 0.1 9.2 5.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.17 EAZ51210.1 - 0.11 11.3 0.2 7.9 5.2 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain TrwB_AAD_bind PF10412.4 EAZ51210.1 - 0.22 10.1 0.3 4.8 5.6 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 EAZ51210.1 - 0.39 10.3 3.5 20 4.7 0.0 3.3 3 0 0 3 3 3 0 NACHT domain FtsK_SpoIIIE PF01580.13 EAZ51210.1 - 1.2 8.6 2.6 0.93 8.9 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ribosomal_L29e PF01779.12 EAZ51211.1 - 1.2e-20 73.0 11.7 1.8e-20 72.5 8.1 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Ribosomal_L18e PF00828.14 EAZ51211.1 - 0.28 11.5 3.4 0.31 11.4 2.3 1.1 1 0 0 1 1 1 0 Ribosomal protein L18e/L15 WD40 PF00400.27 EAZ51212.1 - 1.2e-80 262.7 28.2 5e-14 51.5 0.6 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 EAZ51212.1 - 1.9e-14 53.3 1.5 3.4e-14 52.5 1.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 EAZ51212.1 - 3.8e-08 33.2 0.3 0.00047 19.9 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EAZ51212.1 - 9e-07 27.3 8.6 0.74 7.8 0.1 5.0 1 1 4 5 5 5 5 Nucleoporin Nup120/160 DPPIV_N PF00930.16 EAZ51212.1 - 0.0009 17.9 1.2 0.37 9.3 0.0 3.8 4 0 0 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 EAZ51212.1 - 0.0025 16.9 1.3 14 4.6 0.0 4.1 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EAZ51212.1 - 0.0055 15.5 3.2 1.6 7.4 0.1 3.1 3 1 0 4 4 4 2 Nup133 N terminal like PD40 PF07676.7 EAZ51212.1 - 0.049 13.3 0.3 3.3 7.4 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 EAZ51212.1 - 0.12 10.6 0.1 0.93 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) CoaE PF01121.15 EAZ51213.1 - 6.7e-15 54.9 0.0 7.6e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase 7TM_GPCR_Srt PF10321.4 EAZ51213.1 - 0.024 13.3 0.6 0.025 13.3 0.4 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt Clathrin PF00637.15 EAZ51214.1 - 1e-07 31.6 12.3 1.6e-07 30.9 4.4 2.8 2 1 0 2 2 2 2 Region in Clathrin and VPS SEP PF08059.8 EAZ51215.1 - 1.2e-25 89.5 0.2 2.4e-25 88.6 0.0 1.6 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 EAZ51215.1 - 2.7e-09 36.9 0.0 4.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 UBX domain Peptidase_M6 PF05547.6 EAZ51215.1 - 0.002 16.2 0.1 0.0023 16.0 0.0 1.1 1 0 0 1 1 1 1 Immune inhibitor A peptidase M6 Coatomer_E PF04733.9 EAZ51216.1 - 3e-13 49.5 2.0 7.9e-11 41.6 1.4 2.4 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.12 EAZ51216.1 - 0.0037 17.0 0.0 0.08 12.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EAZ51216.1 - 0.0044 16.6 0.0 0.015 14.9 0.0 1.9 1 0 0 1 1 1 1 TPR repeat Abhydrolase_6 PF12697.2 EAZ51217.1 - 7e-13 48.9 0.0 8.1e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAZ51217.1 - 5.6e-09 35.9 0.0 7.7e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAZ51217.1 - 9.9e-09 35.0 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EAZ51217.1 - 0.00085 17.8 0.0 0.0016 17.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EAZ51217.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Ham1p_like PF01725.11 EAZ51218.1 - 5.7e-48 162.8 0.0 6.5e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family HA2 PF04408.18 EAZ51219.1 - 4.4e-18 65.1 0.2 6e-17 61.5 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EAZ51219.1 - 2.6e-17 62.6 0.5 1.3e-16 60.4 0.3 2.2 1 1 1 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EAZ51219.1 - 7.6e-13 48.1 1.1 1.4e-12 47.2 0.0 2.1 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAZ51219.1 - 1e-08 34.8 0.3 7.9e-08 31.9 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAZ51219.1 - 1.8e-05 24.9 0.0 5.9e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EAZ51219.1 - 0.00045 19.7 0.0 0.00098 18.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EAZ51219.1 - 0.0014 19.0 0.0 0.0014 19.0 0.0 3.7 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 EAZ51219.1 - 0.003 17.8 1.7 0.0065 16.7 0.0 2.5 3 1 0 3 3 3 1 ABC transporter Arch_ATPase PF01637.13 EAZ51219.1 - 0.0046 16.6 0.5 0.0046 16.6 0.3 2.6 3 0 0 3 3 3 1 Archaeal ATPase DUF258 PF03193.11 EAZ51219.1 - 0.0054 15.9 0.0 0.02 14.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 EAZ51219.1 - 0.0092 15.6 0.0 0.033 13.8 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.1 EAZ51219.1 - 0.022 14.3 0.4 0.059 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EAZ51219.1 - 0.024 13.5 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EAZ51219.1 - 0.024 13.8 0.0 0.088 12.0 0.0 2.1 1 1 0 1 1 1 0 PhoH-like protein Miro PF08477.8 EAZ51219.1 - 0.04 14.4 0.0 0.18 12.2 0.0 2.2 1 0 0 1 1 1 0 Miro-like protein AAA_25 PF13481.1 EAZ51219.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAZ51220.1 - 3.9e-29 101.6 0.1 1.5e-17 64.1 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 EAZ51220.1 - 1.6e-06 27.5 0.1 0.0097 15.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EAZ51220.1 - 1.6e-06 28.2 0.0 0.014 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EAZ51220.1 - 4.1e-06 26.9 1.0 0.02 15.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EAZ51220.1 - 4.2e-06 26.0 0.1 0.039 13.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EAZ51220.1 - 0.00017 21.5 1.2 0.027 14.4 0.3 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EAZ51220.1 - 0.00021 22.0 0.2 0.93 10.3 0.0 3.8 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 EAZ51220.1 - 0.00022 21.1 5.3 0.0024 17.7 0.2 3.9 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_10 PF12846.2 EAZ51220.1 - 0.00023 20.6 1.3 0.53 9.6 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain NACHT PF05729.7 EAZ51220.1 - 0.00026 20.6 0.6 0.17 11.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EAZ51220.1 - 0.00026 21.1 0.2 0.92 9.7 0.0 3.2 2 0 0 2 2 2 2 RNA helicase SbcCD_C PF13558.1 EAZ51220.1 - 0.00028 20.7 0.0 0.0015 18.3 0.0 2.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 EAZ51220.1 - 0.00029 19.8 0.0 0.075 11.9 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.24 EAZ51220.1 - 0.00045 20.4 0.1 1.5 9.0 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 EAZ51220.1 - 0.00048 19.4 5.7 0.036 13.2 0.4 2.9 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 EAZ51220.1 - 0.0014 19.0 0.1 0.41 11.1 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 EAZ51220.1 - 0.0016 17.9 0.0 2.4 7.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EAZ51220.1 - 0.0016 17.5 0.1 0.076 12.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin UPF0079 PF02367.12 EAZ51220.1 - 0.0027 17.3 0.1 0.71 9.5 0.0 3.0 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EAZ51220.1 - 0.006 16.0 0.1 0.25 10.8 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 EAZ51220.1 - 0.0097 14.5 0.0 2.8 6.4 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.10 EAZ51220.1 - 0.011 15.4 0.5 4.5 6.9 0.2 2.5 2 0 0 2 2 2 0 NTPase MobB PF03205.9 EAZ51220.1 - 0.014 15.0 0.2 3.6 7.2 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EAZ51220.1 - 0.021 13.7 10.2 0.7 8.6 0.0 3.9 3 1 0 3 3 3 0 NB-ARC domain AAA_33 PF13671.1 EAZ51220.1 - 0.023 14.5 0.1 3 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EAZ51220.1 - 0.027 14.2 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Viral_helicase1 PF01443.13 EAZ51220.1 - 0.029 13.9 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 EAZ51220.1 - 0.07 12.5 2.4 0.38 10.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TGF_beta_GS PF08515.7 EAZ51220.1 - 0.2 10.9 0.0 0.46 9.8 0.0 1.6 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif PduV-EutP PF10662.4 EAZ51220.1 - 0.23 10.9 4.3 7.4 6.0 0.3 3.3 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EAZ51220.1 - 1.1 9.5 9.5 6.2 7.1 0.3 3.8 4 0 0 4 4 3 0 AAA domain UQ_con PF00179.21 EAZ51221.1 - 1.7e-29 102.0 0.1 2.1e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EAZ51221.1 - 0.0011 18.8 0.4 0.0015 18.4 0.3 1.4 1 1 0 1 1 1 1 RWD domain RNase_PH PF01138.16 EAZ51222.1 - 4.1e-13 49.7 0.2 2.9e-12 47.0 0.1 2.2 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 MutS_V PF00488.16 EAZ51223.1 - 2.1e-83 279.3 0.0 3.2e-83 278.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.15 EAZ51223.1 - 4.9e-33 113.5 0.0 1.2e-32 112.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.13 EAZ51223.1 - 3.9e-29 101.9 1.0 3.3e-28 98.8 0.1 2.6 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EAZ51223.1 - 2.8e-06 27.4 2.8 9.2e-06 25.7 2.0 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EAZ51223.1 - 0.0024 17.9 0.0 0.011 15.7 0.0 2.2 1 0 0 1 1 1 1 MutS domain II EBP PF05241.7 EAZ51224.1 - 0.0014 17.7 2.8 0.01 14.8 0.3 2.0 1 1 1 2 2 2 2 Emopamil binding protein UQ_con PF00179.21 EAZ51225.1 - 2.2e-15 56.2 0.0 2.5e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EAZ51225.1 - 0.0017 18.2 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain Thymidylate_kin PF02223.12 EAZ51226.1 - 3.4e-25 88.5 0.0 4.2e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase Sec1 PF00995.18 EAZ51227.1 - 3.9e-130 435.1 14.4 4.5e-130 434.9 9.9 1.0 1 0 0 1 1 1 1 Sec1 family Ric8 PF10165.4 EAZ51228.1 - 0.0023 16.8 0.1 0.0023 16.8 0.1 2.6 1 1 1 2 2 2 1 Guanine nucleotide exchange factor synembryn MinE PF03776.9 EAZ51228.1 - 0.97 8.9 6.7 0.22 11.0 0.3 3.1 3 1 0 3 3 3 0 Septum formation topological specificity factor MinE Metallophos PF00149.23 EAZ51229.1 - 1.1e-30 106.5 1.8 1.4e-30 106.1 1.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sec1 PF00995.18 EAZ51230.1 - 6.4e-92 309.0 9.8 7.8e-92 308.7 6.8 1.0 1 0 0 1 1 1 1 Sec1 family DUF2331 PF10093.4 EAZ51230.1 - 0.008 15.0 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2331) tRNA-synt_1d PF00750.14 EAZ51231.1 - 1.1e-95 320.4 0.7 3.5e-94 315.5 0.5 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EAZ51231.1 - 5.6e-28 97.2 0.1 1e-27 96.4 0.1 1.4 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EAZ51231.1 - 1.3e-17 64.0 0.5 3.2e-17 62.8 0.4 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 EAZ51231.1 - 0.0017 17.5 0.0 0.0032 16.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Syd PF07348.7 EAZ51231.1 - 0.0031 16.8 0.1 0.0078 15.5 0.0 1.7 2 0 0 2 2 2 1 Syd protein (SUKH-2) tRNA-synt_1 PF00133.17 EAZ51231.1 - 0.048 11.6 0.0 0.094 10.7 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EAZ51231.1 - 0.051 12.2 0.0 0.2 10.3 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (M) DUF4325 PF14213.1 EAZ51231.1 - 0.2 11.2 2.8 3.1 7.5 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4325) Dicty_REP PF05086.7 EAZ51232.1 - 0.008 14.0 12.3 0.013 13.3 8.5 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Pex14_N PF04695.8 EAZ51232.1 - 0.01 15.8 0.3 0.025 14.6 0.0 1.9 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mucin PF01456.12 EAZ51232.1 - 0.061 13.0 43.8 0.13 12.0 30.4 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein TT_ORF1 PF02956.9 EAZ51232.1 - 0.28 9.6 8.4 0.16 10.3 0.2 2.3 2 0 0 2 2 2 0 TT viral orf 1 Med3 PF11593.3 EAZ51232.1 - 5.7 6.0 12.4 9.5 5.3 8.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mito_carr PF00153.22 EAZ51235.1 - 1.1e-21 76.2 0.0 1.2e-09 37.7 0.0 3.0 2 1 0 2 2 2 2 Mitochondrial carrier protein MtrD PF04207.7 EAZ51235.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D Pkinase PF00069.20 EAZ51236.1 - 7.1e-60 202.3 0.0 1e-59 201.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51236.1 - 6.8e-18 64.6 0.0 4e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51236.1 - 6.5e-05 22.0 0.0 0.0088 15.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Choline_kinase PF01633.15 EAZ51236.1 - 0.0019 17.8 0.1 0.0032 17.0 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EAZ51236.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EAZ51236.1 - 0.095 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.17 EAZ51237.1 - 7.5e-60 200.9 0.1 9.3e-60 200.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAZ51237.1 - 8.9e-21 74.6 0.0 1.4e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAZ51237.1 - 4.5e-14 52.0 0.0 6.3e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EAZ51237.1 - 2.8e-07 30.4 0.0 4.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAZ51237.1 - 0.00024 20.6 0.0 0.00063 19.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EAZ51237.1 - 0.00049 20.2 0.0 0.0018 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EAZ51237.1 - 0.0024 17.0 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 EAZ51237.1 - 0.0024 17.0 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EAZ51237.1 - 0.0035 16.5 0.1 0.013 14.6 0.0 1.9 1 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EAZ51237.1 - 0.0043 16.9 0.0 0.0097 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EAZ51237.1 - 0.0056 16.1 0.0 0.017 14.5 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EAZ51237.1 - 0.018 14.2 0.0 0.034 13.3 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EAZ51237.1 - 0.027 14.4 0.4 0.071 13.0 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EAZ51237.1 - 0.032 14.5 0.4 0.073 13.3 0.2 2.0 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 EAZ51237.1 - 0.1 11.8 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EAZ51237.1 - 0.14 11.7 0.0 0.39 10.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 EAZ51237.1 - 0.14 11.8 0.2 0.61 9.7 0.1 2.1 2 1 1 3 3 3 0 NTPase HSA PF07529.8 EAZ51239.1 - 1.7e-17 62.9 0.6 1.7e-17 62.9 0.4 3.6 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 EAZ51239.1 - 4.4e-06 26.7 1.6 2e-05 24.5 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAZ51239.1 - 0.0043 17.0 0.0 0.014 15.4 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Peptidase_S24 PF00717.18 EAZ51240.1 - 0.00025 20.6 0.0 0.00043 19.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EAZ51240.1 - 0.00029 20.3 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 KH_1 PF00013.24 EAZ51240.1 - 0.09 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 KH domain AhpC-TSA PF00578.16 EAZ51242.1 - 1.4e-40 137.7 0.0 1.8e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EAZ51242.1 - 3.1e-21 75.4 0.0 3.7e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EAZ51242.1 - 3.4e-13 48.9 0.0 8.7e-13 47.6 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Thioredoxin_8 PF13905.1 EAZ51242.1 - 0.12 12.4 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like SF3b10 PF07189.6 EAZ51243.1 - 1.1e-28 98.8 0.3 1.3e-28 98.6 0.2 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Longin PF13774.1 EAZ51243.1 - 0.054 13.0 0.0 0.062 12.8 0.0 1.3 1 1 0 1 1 1 0 Regulated-SNARE-like domain DUF4494 PF14902.1 EAZ51243.1 - 0.088 12.4 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4494) RRM_1 PF00076.17 EAZ51244.1 - 2.9e-17 62.0 0.9 6.5e-17 60.9 0.2 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAZ51244.1 - 2e-14 53.3 0.1 4.6e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAZ51244.1 - 4.8e-08 32.7 0.2 9.8e-08 31.7 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.3 EAZ51244.1 - 2.4e-07 30.7 0.5 7.5e-07 29.1 0.4 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G L_lac_phage_MSP PF06488.6 EAZ51244.1 - 0.0062 15.6 0.3 0.013 14.5 0.2 1.5 1 0 0 1 1 1 1 Lactococcus lactis bacteriophage major structural protein DUF3153 PF11353.3 EAZ51244.1 - 0.064 12.6 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) chaperone_DMP PF10448.4 EAZ51244.1 - 2.4 8.0 9.1 0.51 10.2 0.6 2.3 2 0 0 2 2 2 0 20S proteasome chaperone zf-MYND PF01753.13 EAZ51245.1 - 2.9e-11 43.0 15.1 5.1e-11 42.2 10.5 1.4 1 0 0 1 1 1 1 MYND finger YafO_toxin PF13957.1 EAZ51245.1 - 0.074 12.8 0.8 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Toxin YafO, type II toxin-antitoxin system DUF3846 PF12957.2 EAZ51245.1 - 0.083 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) CARD PF00619.16 EAZ51245.1 - 0.099 12.4 0.9 2.3 8.1 0.0 2.7 3 0 0 3 3 3 0 Caspase recruitment domain RCC1 PF00415.13 EAZ51246.1 - 4.9e-38 129.1 0.0 1.4e-05 25.2 0.0 9.0 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EAZ51246.1 - 3.4e-23 80.6 23.8 4e-08 32.6 0.1 7.9 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Daxx PF03344.10 EAZ51246.1 - 1.1 7.7 86.1 0.31 9.4 5.9 2.5 2 0 0 2 2 2 0 Daxx Family LSM PF01423.17 EAZ51247.1 - 1.8e-16 59.3 0.4 2.5e-16 58.9 0.2 1.2 1 0 0 1 1 1 1 LSM domain YabP PF07873.6 EAZ51247.1 - 0.0045 16.5 0.1 0.11 12.0 0.0 2.1 2 0 0 2 2 2 1 YabP family CBFD_NFYB_HMF PF00808.18 EAZ51248.1 - 5.2e-15 55.2 0.0 2.5e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EAZ51248.1 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Phospholip_A2_3 PF09056.6 EAZ51248.1 - 0.17 12.1 5.2 0.28 11.3 2.1 2.3 1 1 1 2 2 2 0 Prokaryotic phospholipase A2 Rad51 PF08423.6 EAZ51249.1 - 1.7e-10 40.2 0.0 2.6e-10 39.6 0.0 1.3 1 1 0 1 1 1 1 Rad51 AAA_22 PF13401.1 EAZ51249.1 - 4.5e-05 23.6 0.0 5.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAZ51249.1 - 9.3e-05 23.2 0.0 0.00011 23.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAZ51249.1 - 9.7e-05 22.6 0.6 0.00012 22.3 0.4 1.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EAZ51249.1 - 0.00073 19.7 0.1 0.0011 19.1 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EAZ51249.1 - 0.015 15.1 0.1 0.018 14.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EAZ51249.1 - 0.019 14.0 1.1 0.04 13.0 0.8 1.7 1 1 0 1 1 1 0 KaiC RNA_helicase PF00910.17 EAZ51249.1 - 0.023 14.8 0.0 0.03 14.4 0.0 1.4 1 1 0 1 1 1 0 RNA helicase DUF4252 PF14060.1 EAZ51249.1 - 0.049 13.1 0.3 0.066 12.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) RNA_pol_Rpb4 PF03874.11 EAZ51249.1 - 0.05 13.6 0.0 0.056 13.4 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb4 AAA_19 PF13245.1 EAZ51249.1 - 0.055 13.2 0.2 0.075 12.7 0.1 1.5 1 1 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 EAZ51249.1 - 0.057 13.0 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Peptidase_C1 PF00112.18 EAZ51250.1 - 2.7e-40 138.5 3.9 2.7e-40 138.5 2.7 1.8 2 0 0 2 2 2 1 Papain family cysteine protease CathepsinC_exc PF08773.6 EAZ51250.1 - 4.1e-08 33.4 0.2 2.8e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.10 EAZ51250.1 - 0.029 12.9 0.4 0.029 12.9 0.3 1.5 2 0 0 2 2 2 0 Peptidase C1-like family RNase_HII PF01351.13 EAZ51251.1 - 3.2e-13 49.7 0.0 1.5e-12 47.5 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease HII SMC_N PF02463.14 EAZ51252.1 - 6.6e-56 188.9 41.8 1.3e-53 181.5 29.0 3.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EAZ51252.1 - 1.1e-19 70.5 0.0 4.2e-19 68.6 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 EAZ51252.1 - 9.2e-05 21.8 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IncA PF04156.9 EAZ51252.1 - 0.0015 18.1 14.4 0.0015 18.1 10.0 7.3 2 2 5 7 7 7 2 IncA protein AAA_21 PF13304.1 EAZ51252.1 - 0.0025 17.8 72.0 0.012 15.6 17.5 5.8 2 2 2 4 4 4 2 AAA domain FlxA PF14282.1 EAZ51252.1 - 0.0096 15.8 2.4 0.0096 15.8 1.7 8.1 4 2 4 9 9 9 1 FlxA-like protein TPR_MLP1_2 PF07926.7 EAZ51252.1 - 0.01 15.6 3.0 0.01 15.6 2.1 7.8 2 2 5 8 8 8 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EAZ51252.1 - 0.06 12.5 29.6 0.016 14.4 4.1 4.9 2 2 4 6 6 6 0 Reovirus sigma C capsid protein AAA_23 PF13476.1 EAZ51252.1 - 1.9 8.7 142.0 0.2 11.9 43.6 6.5 2 2 1 3 3 3 0 AAA domain DUF2968 PF11180.3 EAZ51252.1 - 2.2 7.6 25.4 0.71 9.2 0.8 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) adh_short PF00106.20 EAZ51253.1 - 4.2e-17 62.5 0.0 6.7e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAZ51253.1 - 9.9e-08 31.8 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 KR domain ThiF PF00899.16 EAZ51253.1 - 0.00056 19.7 0.0 0.00092 19.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family Polysacc_synt_2 PF02719.10 EAZ51253.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EAZ51253.1 - 0.11 12.2 0.2 0.49 10.2 0.0 2.0 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase WD40 PF00400.27 EAZ51254.1 - 1.5e-30 103.9 25.5 1e-06 28.3 0.6 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PFU PF09070.6 EAZ51254.1 - 4.6e-15 55.6 1.4 1.1e-14 54.4 0.3 2.1 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 EAZ51254.1 - 2.6e-14 52.6 9.6 6.9e-14 51.2 6.7 1.6 1 0 0 1 1 1 1 PUL domain GDPD PF03009.12 EAZ51255.1 - 9.3e-42 143.2 0.0 1.2e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Epimerase PF01370.16 EAZ51256.1 - 1.3e-48 165.4 0.0 1.6e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EAZ51256.1 - 2.9e-25 87.9 0.1 6.1e-25 86.9 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EAZ51256.1 - 2e-16 59.5 0.0 4.9e-16 58.2 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EAZ51256.1 - 2.4e-15 56.2 0.0 2.2e-14 53.0 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EAZ51256.1 - 4.6e-10 38.8 0.0 1e-09 37.7 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EAZ51256.1 - 1.8e-08 33.6 0.0 3e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EAZ51256.1 - 9.8e-08 32.0 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAZ51256.1 - 2e-05 24.3 0.0 3.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EAZ51256.1 - 0.00016 21.7 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAZ51256.1 - 0.0078 15.4 0.0 0.05 12.8 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Chal_sti_synt_N PF00195.14 EAZ51256.1 - 0.085 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain LSM PF01423.17 EAZ51257.1 - 0.0054 16.2 1.1 0.011 15.2 0.2 1.8 2 0 0 2 2 2 1 LSM domain HDA2-3 PF11496.3 EAZ51257.1 - 0.0055 15.5 0.0 0.0056 15.5 0.0 1.0 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Glycos_transf_1 PF00534.15 EAZ51258.1 - 2.7e-13 49.6 0.0 1.1e-12 47.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Ku_PK_bind PF08785.6 EAZ51258.1 - 0.0091 15.8 1.9 0.037 13.9 0.5 2.1 1 1 1 2 2 2 1 Ku C terminal domain like LSM PF01423.17 EAZ51260.1 - 5.1e-18 64.3 0.2 6.5e-18 64.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain RNA_pol_L_2 PF13656.1 EAZ51261.1 - 1.8e-10 40.0 0.2 1.8e-09 36.8 0.1 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_N PF01194.12 EAZ51262.1 - 1.2e-29 102.1 0.3 1.4e-29 101.9 0.2 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit HSP70 PF00012.15 EAZ51263.1 - 3.7e-115 385.1 2.7 4.9e-115 384.7 0.1 2.2 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EAZ51263.1 - 0.00094 17.8 3.4 0.0017 17.0 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.11 EAZ51263.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Pkinase PF00069.20 EAZ51264.1 - 2.3e-70 236.7 0.0 3.5e-70 236.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51264.1 - 1e-40 139.4 0.0 1.8e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 EAZ51264.1 - 1.5e-34 117.9 6.7 2.9e-11 43.3 0.2 4.4 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 EAZ51264.1 - 1.9e-32 108.0 11.2 5e-06 25.4 0.1 6.9 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.1 EAZ51264.1 - 3.1e-26 88.8 7.5 6e-05 22.6 0.0 6.9 6 0 0 6 6 6 6 EF-hand domain EF-hand_8 PF13833.1 EAZ51264.1 - 2.2e-19 68.7 6.7 7.3e-06 25.5 0.1 5.7 5 1 1 6 6 6 5 EF-hand domain pair EF-hand_5 PF13202.1 EAZ51264.1 - 4.7e-18 63.6 8.5 2.5e-06 26.5 0.2 5.6 6 0 0 6 6 6 4 EF hand SPARC_Ca_bdg PF10591.4 EAZ51264.1 - 7.3e-07 29.2 2.9 0.0037 17.2 0.0 3.8 4 0 0 4 4 3 2 Secreted protein acidic and rich in cysteine Ca binding region Pox_ser-thr_kin PF05445.6 EAZ51264.1 - 6.6e-06 25.1 0.7 1.7e-05 23.8 0.5 1.7 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EAZ51264.1 - 8.6e-06 24.9 0.2 1.6e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAZ51264.1 - 1.3e-05 24.2 0.0 3.5e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like EF-hand_4 PF12763.2 EAZ51264.1 - 3.5e-05 23.4 2.4 0.61 9.8 0.0 4.7 3 1 1 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EAZ51264.1 - 0.00037 20.0 0.7 0.01 15.5 0.0 3.7 4 0 0 4 4 4 1 EF hand YrbL-PhoP_reg PF10707.4 EAZ51264.1 - 0.0012 18.1 0.0 0.0026 17.1 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EAZ51264.1 - 0.0055 16.3 0.3 0.014 14.9 0.2 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EAZ51264.1 - 0.0069 16.1 0.0 0.44 10.2 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Mob1_phocein PF03637.12 EAZ51265.1 - 9.8e-39 132.8 2.0 1.6e-38 132.1 1.4 1.3 1 0 0 1 1 1 1 Mob1/phocein family RRM_1 PF00076.17 EAZ51266.1 - 6.1e-47 157.1 0.1 2e-14 52.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAZ51266.1 - 9.6e-36 121.6 0.2 2.4e-12 46.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAZ51266.1 - 7e-30 102.6 0.1 5e-09 35.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 EAZ51266.1 - 5.2e-10 39.0 1.9 5.2e-10 39.0 1.3 2.2 2 0 0 2 2 2 1 WW domain RNA_bind PF08675.6 EAZ51266.1 - 0.0062 16.4 0.0 2.5 8.1 0.0 3.3 3 0 0 3 3 3 1 RNA binding domain SPC12 PF06645.8 EAZ51267.1 - 2.3e-11 43.3 1.0 3.8e-11 42.6 0.7 1.4 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MAGE PF01454.14 EAZ51267.1 - 0.03 13.6 0.5 0.057 12.7 0.3 1.6 1 1 0 1 1 1 0 MAGE family MerC PF03203.9 EAZ51267.1 - 0.03 14.6 0.1 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 MerC mercury resistance protein DUF872 PF05915.7 EAZ51267.1 - 0.13 12.0 0.3 0.25 11.1 0.2 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) RabGAP-TBC PF00566.13 EAZ51268.1 - 2.7e-30 105.4 10.7 2.7e-30 105.4 7.4 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ArfGap PF01412.13 EAZ51269.1 - 1.4e-25 89.3 0.9 1.4e-25 89.3 0.6 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf zf-B_box PF00643.19 EAZ51269.1 - 0.0043 16.9 1.4 0.0075 16.1 0.9 1.4 1 0 0 1 1 1 1 B-box zinc finger Mitofilin PF09731.4 EAZ51270.1 - 0.0031 16.2 8.5 0.0031 16.2 5.9 2.4 2 1 0 2 2 2 1 Mitochondrial inner membrane protein Atrophin-1 PF03154.10 EAZ51270.1 - 8.7 4.3 19.3 16 3.4 13.4 1.3 1 0 0 1 1 1 0 Atrophin-1 family Pkinase PF00069.20 EAZ51271.1 - 5.1e-49 166.7 0.0 3e-48 164.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51271.1 - 2.3e-20 72.7 0.0 4.1e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_11 PF13414.1 EAZ51273.1 - 1.5e-07 30.9 0.8 1.9e-07 30.6 0.5 1.2 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EAZ51273.1 - 2.9e-05 23.4 2.5 0.007 15.9 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAZ51273.1 - 0.00015 21.4 0.2 0.35 10.9 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAZ51273.1 - 0.0063 16.3 0.2 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fringe PF02434.11 EAZ51274.1 - 9.3e-16 57.7 3.4 1.4e-08 34.2 0.2 3.0 2 1 1 3 3 3 3 Fringe-like Beta-Casp PF10996.3 EAZ51275.1 - 4.6e-10 39.5 0.7 2.1e-09 37.3 0.0 2.5 2 0 0 2 2 2 1 Beta-Casp domain tRNA-synt_1 PF00133.17 EAZ51277.1 - 3.9e-17 61.4 0.1 1.7e-07 29.6 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EAZ51277.1 - 4.7e-09 35.8 0.0 9.9e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EAZ51277.1 - 2.4e-08 33.0 0.5 9.6e-07 27.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) WD40 PF00400.27 EAZ51278.1 - 1.5e-18 65.8 0.3 3.3e-08 33.1 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat RNA_pol_Rpb1_5 PF04998.12 EAZ51279.1 - 9.3e-66 221.9 0.6 1.6e-64 217.8 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EAZ51279.1 - 8.1e-56 188.5 0.1 3.8e-55 186.3 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EAZ51279.1 - 1.3e-28 99.6 0.0 1.3e-28 99.6 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EAZ51279.1 - 1.7e-23 83.4 1.0 1.7e-23 83.4 0.7 5.0 5 0 0 5 5 5 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EAZ51279.1 - 6e-16 58.1 3.1 7.7e-16 57.7 0.0 2.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 C2 PF00168.25 EAZ51280.1 - 5.5e-07 29.3 0.0 2.2e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 C2 domain KLRAQ PF10205.4 EAZ51281.1 - 0.0029 17.6 0.7 0.0058 16.6 0.1 1.9 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein ER PF01133.12 EAZ51281.1 - 0.066 12.9 0.5 0.18 11.5 0.1 2.0 1 1 0 1 1 1 0 Enhancer of rudimentary TBPIP PF07106.8 EAZ51281.1 - 0.088 12.3 4.7 0.15 11.5 3.3 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin PF00804.20 EAZ51281.1 - 3.6 7.8 8.9 14 5.8 6.2 2.0 1 1 0 1 1 1 0 Syntaxin Prefoldin PF02996.12 EAZ51282.1 - 3.3e-21 75.1 0.2 5.3e-21 74.4 0.1 1.4 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EAZ51282.1 - 0.0026 17.5 0.8 0.15 11.8 0.0 2.3 2 1 0 2 2 2 2 Prefoldin subunit WD40 PF00400.27 EAZ51283.1 - 4.5e-40 134.1 17.7 6.3e-08 32.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EAZ51283.1 - 6.1e-14 50.9 1.2 1e-13 50.2 0.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nucleoporin_N PF08801.6 EAZ51283.1 - 9.9e-06 24.5 11.6 0.077 11.7 0.0 3.8 1 1 3 4 4 4 3 Nup133 N terminal like Topoisom_bac PF01131.15 EAZ51284.1 - 2.4e-87 293.4 0.0 3.7e-87 292.7 0.0 1.3 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EAZ51284.1 - 1.1e-13 51.0 0.0 3.5e-13 49.3 0.0 2.0 1 0 0 1 1 1 1 Toprim domain DUF2024 PF09630.5 EAZ51284.1 - 0.053 13.2 0.8 5.5 6.7 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) Actin PF00022.14 EAZ51285.1 - 4.6e-49 166.8 0.0 7.1e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Actin Steroid_dh PF02544.11 EAZ51286.1 - 3.9e-17 62.4 13.1 3.9e-17 62.4 9.1 2.2 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EAZ51286.1 - 0.0037 16.6 3.3 0.0059 15.9 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ribosomal_L3 PF00297.17 EAZ51287.1 - 4.3e-88 295.1 0.7 4.9e-88 294.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3586 PF12131.3 EAZ51287.1 - 0.034 14.1 0.6 0.075 13.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) MORN PF02493.15 EAZ51288.1 - 6.9e-64 207.9 72.0 3.4e-09 35.8 2.1 12.7 13 0 0 13 13 13 12 MORN repeat DJ-1_PfpI PF01965.19 EAZ51289.1 - 8.6e-21 73.9 0.0 1.1e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EAZ51289.1 - 2.7e-11 43.0 0.0 3.8e-11 42.5 0.0 1.3 1 1 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 EAZ51289.1 - 0.027 14.0 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Proteasome PF00227.21 EAZ51290.1 - 9.7e-55 184.7 0.2 1.4e-54 184.2 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAZ51290.1 - 1.1e-13 50.1 0.1 1.9e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ATP_bind_1 PF03029.12 EAZ51291.1 - 9.6e-72 241.3 0.1 1.2e-71 241.0 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EAZ51291.1 - 2.3e-05 23.9 0.0 6.2e-05 22.4 0.0 1.8 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.22 EAZ51291.1 - 0.0001 21.7 0.0 0.00027 20.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dor1 PF04124.7 EAZ51291.1 - 0.032 12.7 0.1 0.042 12.3 0.1 1.2 1 0 0 1 1 1 0 Dor1-like family ArsA_ATPase PF02374.10 EAZ51291.1 - 0.063 12.3 0.2 1.1 8.2 0.0 2.6 3 0 0 3 3 3 0 Anion-transporting ATPase DUF421 PF04239.7 EAZ51291.1 - 0.077 12.5 0.1 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF421) AAA_16 PF13191.1 EAZ51291.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 EAZ51291.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 EAZ51291.1 - 0.33 11.2 5.2 3.1 8.0 3.6 2.0 1 1 0 1 1 1 0 AAA domain M60-like PF13402.1 EAZ51292.1 - 4.2e-35 121.1 0.9 1.8e-32 112.4 0.1 2.3 2 0 0 2 2 2 2 Peptidase M60-like family Glycos_transf_2 PF00535.21 EAZ51293.1 - 1e-36 126.2 0.0 1.3e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 EAZ51293.1 - 9.1e-14 51.2 0.0 1.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 EAZ51293.1 - 1.8e-13 50.8 0.0 2.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EAZ51293.1 - 1.2e-05 24.6 0.0 1.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_5 PF13712.1 EAZ51293.1 - 0.011 15.0 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family Glyco_tranf_2_4 PF13704.1 EAZ51293.1 - 0.053 13.8 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EAZ51293.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DNA_methylase PF00145.12 EAZ51294.1 - 3.7e-18 65.7 1.7 5.7e-18 65.1 1.2 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase EF-hand_7 PF13499.1 EAZ51295.1 - 5.6e-07 29.5 0.1 0.00073 19.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EAZ51295.1 - 1.2e-06 27.8 0.1 0.0013 18.3 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 EAZ51295.1 - 1.8e-05 23.6 0.5 0.0005 19.1 0.1 2.8 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 EAZ51295.1 - 0.00011 21.6 0.1 0.037 13.6 0.0 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 EAZ51295.1 - 0.02 14.8 0.0 0.048 13.5 0.0 1.6 2 0 0 2 2 2 0 EF-hand domain Avirulence PF03377.8 EAZ51295.1 - 0.036 12.8 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA EF-hand_5 PF13202.1 EAZ51295.1 - 0.037 13.3 0.3 0.64 9.4 0.1 2.4 2 0 0 2 2 2 0 EF hand DUF4007 PF13182.1 EAZ51295.1 - 0.044 12.6 0.0 0.05 12.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4007) RNA_pol_Rpb4 PF03874.11 EAZ51295.1 - 0.13 12.2 0.1 0.71 9.9 0.0 1.9 1 1 0 2 2 2 0 RNA polymerase Rpb4 Pkinase PF00069.20 EAZ51296.1 - 5.2e-32 111.0 0.1 7.2e-32 110.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51296.1 - 4.4e-12 45.6 0.1 8.5e-12 44.6 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAZ51296.1 - 0.00011 21.3 0.0 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PapC_N PF13954.1 EAZ51297.1 - 0.014 15.0 0.4 0.024 14.2 0.3 1.3 1 0 0 1 1 1 0 PapC N-terminal domain Methyltransf_31 PF13847.1 EAZ51297.1 - 0.037 13.6 0.7 0.061 12.9 0.5 1.5 1 0 0 1 1 1 0 Methyltransferase domain SNF2_N PF00176.18 EAZ51298.1 - 1.3e-48 165.3 5.9 5.6e-48 163.2 4.1 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EAZ51298.1 - 7.4e-13 48.7 0.0 7.4e-13 48.7 0.0 2.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EAZ51298.1 - 8.5e-07 28.6 0.0 0.007 15.8 0.0 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase DUF1694 PF07997.6 EAZ51298.1 - 0.023 14.6 2.3 0.078 12.9 1.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) Helicase_C PF00271.26 EAZ51299.1 - 0.0027 17.5 0.1 0.0062 16.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain KH_5 PF13184.1 EAZ51299.1 - 0.063 13.0 4.1 7.9 6.3 0.1 3.4 2 1 0 2 2 2 0 NusA-like KH domain HNH PF01844.18 EAZ51299.1 - 0.066 13.0 0.2 5.3 7.0 0.1 2.7 2 0 0 2 2 2 0 HNH endonuclease Sec63 PF02889.11 EAZ51300.1 - 3.2e-41 141.5 7.5 4.8e-41 140.9 5.2 1.2 1 0 0 1 1 1 1 Sec63 Brl domain PPO1_KFDV PF12143.3 EAZ51300.1 - 0.035 14.0 0.2 0.085 12.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) TM1506 PF08973.5 EAZ51300.1 - 0.046 13.2 0.1 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) DCX PF03607.12 EAZ51302.1 - 7.5e-09 35.0 0.0 1.9e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Doublecortin p25-alpha PF05517.7 EAZ51302.1 - 3.7e-07 30.5 0.7 8.7e-07 29.3 0.3 1.7 1 1 0 1 1 1 1 p25-alpha AIF_C PF14721.1 EAZ51302.1 - 0.52 10.5 3.0 4.5 7.5 0.1 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Cullin PF00888.17 EAZ51303.1 - 5.5e-20 71.4 8.0 8e-10 37.8 0.7 5.2 4 2 0 4 4 4 4 Cullin family Actin PF00022.14 EAZ51304.1 - 5.4e-153 509.0 0.0 6.1e-153 508.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EAZ51304.1 - 0.018 15.3 0.1 0.14 12.6 0.0 2.1 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Phosphodiest PF01663.17 EAZ51304.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sod_Fe_C PF02777.13 EAZ51305.1 - 4.8e-39 132.4 2.1 1.2e-38 131.1 0.1 2.1 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EAZ51305.1 - 3e-30 104.3 0.1 7e-30 103.1 0.1 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain RRM_1 PF00076.17 EAZ51306.1 - 1.8e-29 101.1 1.2 1.4e-13 50.2 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAZ51306.1 - 4.6e-27 93.8 0.3 1.5e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAZ51306.1 - 2.6e-14 52.7 1.0 5e-08 32.6 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EAZ51306.1 - 0.019 14.4 0.3 5.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Nup35_RRM PF05172.8 EAZ51306.1 - 0.045 13.5 2.4 0.47 10.2 0.2 2.5 1 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Pro_isomerase PF00160.16 EAZ51307.1 - 4.3e-39 134.2 0.1 5e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M16 PF00675.15 EAZ51308.1 - 2.7e-46 157.0 0.0 4.7e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAZ51308.1 - 1.9e-14 53.7 0.2 3.5e-13 49.6 0.1 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain LOH1CR12 PF10158.4 EAZ51308.1 - 0.1 12.3 0.1 11 5.8 0.1 2.3 2 0 0 2 2 2 0 Tumour suppressor protein GrpE PF01025.14 EAZ51309.1 - 1.2e-47 161.4 2.1 1.6e-47 161.1 1.5 1.1 1 0 0 1 1 1 1 GrpE DsrC PF04358.8 EAZ51309.1 - 0.043 14.0 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 DsrC like protein Pkinase PF00069.20 EAZ51310.1 - 2.5e-61 207.0 0.0 2.8e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51310.1 - 1.5e-33 115.9 0.0 1.8e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EAZ51310.1 - 0.01 14.6 1.0 0.016 14.0 0.7 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EAZ51310.1 - 0.022 13.8 0.0 0.055 12.5 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EAZ51310.1 - 0.029 13.7 1.2 1.6 8.0 0.1 2.3 1 1 1 2 2 2 0 RIO1 family APH PF01636.18 EAZ51310.1 - 0.098 12.3 0.0 0.29 10.8 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Arf PF00025.16 EAZ51311.1 - 9e-70 233.4 0.2 1e-69 233.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EAZ51311.1 - 4.1e-10 38.9 1.5 2.9e-05 22.9 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EAZ51311.1 - 2.9e-09 36.5 0.0 3.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EAZ51311.1 - 1.4e-08 34.1 0.0 1.7e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EAZ51311.1 - 1.6e-08 35.0 0.0 2.1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EAZ51311.1 - 1.9e-07 30.5 0.0 2.5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EAZ51311.1 - 2e-06 27.7 0.0 2.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAZ51311.1 - 0.0034 16.8 0.0 0.066 12.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EAZ51311.1 - 0.014 14.6 0.0 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B 6PF2K PF01591.13 EAZ51311.1 - 0.14 11.1 0.2 1.7 7.6 0.1 2.0 1 1 1 2 2 2 0 6-phosphofructo-2-kinase DEAD PF00270.24 EAZ51312.1 - 3.3e-42 143.8 0.0 1.1e-41 142.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAZ51312.1 - 1.7e-26 91.9 0.3 4.6e-25 87.2 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAZ51312.1 - 3.7e-08 33.4 0.0 1.1e-06 28.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EAZ51312.1 - 0.2 11.8 3.8 4.9 7.2 1.2 3.5 2 1 0 2 2 2 0 AAA domain Proteasome PF00227.21 EAZ51313.1 - 2.4e-29 101.9 0.0 2.9e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit AF0941-like PF14591.1 EAZ51313.1 - 0.11 12.6 0.0 2.9 7.9 0.0 2.2 2 0 0 2 2 2 0 AF0941-like Peptidase_S24 PF00717.18 EAZ51314.1 - 7e-10 38.4 0.2 1e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like DNA_ligase_OB PF03120.11 EAZ51314.1 - 0.033 13.8 0.1 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent DNA ligase OB-fold domain Exo5 PF09810.4 EAZ51315.1 - 1.5e-102 343.1 4.6 1.8e-102 342.8 3.2 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Nop10p PF04135.7 EAZ51316.1 - 1.5e-20 72.6 0.0 1.7e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF1093 PF06486.6 EAZ51316.1 - 0.14 12.5 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1093) Phage-tail_2 PF09096.5 EAZ51317.1 - 0.012 15.3 0.3 0.024 14.2 0.0 1.7 2 0 0 2 2 2 0 Baseplate structural protein, domain 2 Dynamin_M PF01031.15 EAZ51318.1 - 4.1e-86 288.4 0.1 1.4e-85 286.6 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EAZ51318.1 - 1e-28 100.2 0.0 1e-28 100.2 0.0 2.4 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 EAZ51318.1 - 4.1e-23 81.0 1.1 4.1e-23 81.0 0.8 3.3 4 0 0 4 4 4 1 Dynamin GTPase effector domain Peptidase_M41 PF01434.13 EAZ51318.1 - 0.093 12.1 0.3 0.29 10.5 0.2 1.8 1 0 0 1 1 1 0 Peptidase family M41 Mito_carr PF00153.22 EAZ51319.1 - 9.2e-44 147.0 0.3 1.3e-17 63.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AAA_13 PF13166.1 EAZ51320.1 - 6.2e-05 21.6 20.7 6.2e-05 21.6 14.4 2.4 2 1 1 3 3 3 1 AAA domain SlyX PF04102.7 EAZ51320.1 - 0.018 15.3 34.4 0.034 14.5 3.5 4.6 2 2 2 4 4 4 0 SlyX Atg14 PF10186.4 EAZ51320.1 - 0.04 12.8 48.3 0.054 12.4 25.5 2.7 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 EAZ51320.1 - 0.16 11.7 69.8 0.87 9.4 15.7 4.6 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 EAZ51320.1 - 0.2 10.7 18.4 0.018 14.2 7.0 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Sipho_Gp157 PF05565.6 EAZ51320.1 - 0.39 10.2 42.3 2.5 7.6 6.0 3.5 1 1 2 3 3 3 0 Siphovirus Gp157 ATG16 PF08614.6 EAZ51320.1 - 2.1 8.1 53.3 4.4e+02 0.5 27.8 3.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Macoilin PF09726.4 EAZ51320.1 - 3.6 5.7 42.5 5.7 5.0 29.4 1.3 1 0 0 1 1 1 0 Transmembrane protein ABC_tran PF00005.22 EAZ51322.1 - 9.3e-53 178.1 3.9 1.1e-30 106.6 0.3 3.1 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EAZ51322.1 - 2.1e-08 33.7 9.1 0.0059 15.8 0.2 4.0 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EAZ51322.1 - 3e-07 29.6 1.0 0.022 13.6 0.0 2.7 3 0 0 3 3 2 2 Type II/IV secretion system protein ABC_membrane PF00664.18 EAZ51322.1 - 3.1e-07 30.0 42.7 4e-05 23.1 11.6 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.1 EAZ51322.1 - 4.9e-07 29.1 0.8 0.0014 18.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EAZ51322.1 - 1.2e-06 27.7 1.4 0.013 14.7 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 NB-ARC PF00931.17 EAZ51322.1 - 1.6e-06 27.1 0.7 0.051 12.4 0.1 2.7 2 0 0 2 2 2 2 NB-ARC domain AAA_17 PF13207.1 EAZ51322.1 - 2.5e-06 28.3 3.9 0.12 13.2 0.0 4.2 4 0 0 4 4 3 2 AAA domain MobB PF03205.9 EAZ51322.1 - 2.6e-06 27.1 0.9 0.01 15.5 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EAZ51322.1 - 6.2e-06 26.1 5.6 0.059 13.3 0.0 4.1 4 1 0 4 4 4 2 50S ribosome-binding GTPase ArgK PF03308.11 EAZ51322.1 - 1.1e-05 24.3 0.0 0.058 12.1 0.0 2.2 2 0 0 2 2 2 2 ArgK protein AAA_16 PF13191.1 EAZ51322.1 - 1.7e-05 24.8 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain cobW PF02492.14 EAZ51322.1 - 2.1e-05 24.0 1.2 0.021 14.2 0.1 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EAZ51322.1 - 3.7e-05 23.8 2.0 0.099 12.7 0.1 3.6 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EAZ51322.1 - 4.3e-05 23.8 4.6 0.16 12.3 0.0 3.8 4 0 0 4 4 2 2 AAA domain Miro PF08477.8 EAZ51322.1 - 5.5e-05 23.6 4.2 0.1 13.0 0.1 3.2 3 0 0 3 3 2 2 Miro-like protein DUF87 PF01935.12 EAZ51322.1 - 0.00018 21.4 7.6 0.026 14.3 0.2 2.9 3 0 0 3 3 2 2 Domain of unknown function DUF87 AAA_10 PF12846.2 EAZ51322.1 - 0.00055 19.4 0.1 0.088 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain Zeta_toxin PF06414.7 EAZ51322.1 - 0.00085 18.4 0.3 0.64 9.0 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA PF00004.24 EAZ51322.1 - 0.00094 19.3 0.2 0.61 10.2 0.0 3.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EAZ51322.1 - 0.0014 18.1 0.0 0.091 12.2 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family GTP_EFTU PF00009.22 EAZ51322.1 - 0.002 17.6 2.4 0.34 10.3 0.0 3.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.4 EAZ51322.1 - 0.0038 15.8 6.7 0.0042 15.7 0.6 3.0 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_33 PF13671.1 EAZ51322.1 - 0.0055 16.5 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EAZ51322.1 - 0.0059 16.2 0.6 2.4 7.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EAZ51322.1 - 0.009 15.7 0.1 3.9 7.3 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain ATP_bind_1 PF03029.12 EAZ51322.1 - 0.01 15.4 0.5 9.2 5.7 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 EAZ51322.1 - 0.016 14.8 6.7 1.2 8.8 0.0 3.9 4 0 0 4 4 4 0 NTPase DUF815 PF05673.8 EAZ51322.1 - 0.017 14.0 0.1 0.12 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.18 EAZ51322.1 - 0.021 14.6 3.7 2.6 7.8 0.1 3.5 3 0 0 3 3 3 0 Dynamin family AAA_5 PF07728.9 EAZ51322.1 - 0.026 14.2 0.8 33 4.2 0.0 4.0 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 EAZ51322.1 - 0.037 12.6 0.7 4.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SbcCD_C PF13558.1 EAZ51322.1 - 0.065 13.1 0.0 21 5.1 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EAZ51322.1 - 0.086 12.4 0.1 6.6 6.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain SPRY PF00622.23 EAZ51323.1 - 5.7e-10 39.3 0.1 0.00012 22.1 0.0 2.4 2 0 0 2 2 2 2 SPRY domain ubiquitin PF00240.18 EAZ51324.1 - 4e-07 29.3 0.2 9.2e-07 28.1 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EAZ51324.1 - 1.1e-05 25.5 0.1 4e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 EAZ51324.1 - 0.015 14.9 0.3 0.11 12.1 0.2 2.0 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DEAD PF00270.24 EAZ51325.1 - 4.2e-42 143.4 0.3 5.3e-41 139.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAZ51325.1 - 1.3e-28 98.6 0.8 1.7e-27 95.1 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EAZ51325.1 - 0.00016 20.8 0.0 0.00037 19.6 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EAZ51325.1 - 0.0012 18.5 0.2 0.0066 16.1 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain DUF1253 PF06862.7 EAZ51325.1 - 0.0016 16.9 0.0 0.19 10.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) ResIII PF04851.10 EAZ51325.1 - 0.0039 17.0 0.0 0.0099 15.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EAZ51325.1 - 0.0061 16.1 0.0 0.017 14.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Pkinase PF00069.20 EAZ51326.1 - 6.9e-32 110.6 0.0 1.1e-17 64.0 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51326.1 - 2.5e-16 59.5 0.0 3.8e-12 45.8 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 EAZ51326.1 - 0.0079 15.2 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAZ51326.1 - 0.1 11.5 0.0 0.29 10.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EAZ51326.1 - 0.13 11.9 0.0 0.37 10.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family NifZ PF04319.8 EAZ51326.1 - 0.14 11.5 0.0 0.46 9.9 0.0 1.8 1 0 0 1 1 1 0 NifZ domain PQQ PF01011.16 EAZ51326.1 - 0.3 10.7 1.7 4.4 7.0 0.1 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat ABC_tran PF00005.22 EAZ51327.1 - 1.4e-36 125.8 0.0 6.1e-18 65.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EAZ51327.1 - 1.6e-14 53.1 2.9 4.1e-14 51.8 2.0 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EAZ51327.1 - 1.1e-12 48.5 3.9 0.00011 22.2 0.1 4.3 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EAZ51327.1 - 5.1e-11 42.2 4.8 0.0015 17.8 0.1 3.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EAZ51327.1 - 3e-07 29.8 2.2 0.043 12.8 0.0 3.5 4 0 0 4 4 4 2 AAA ATPase domain Fer4 PF00037.22 EAZ51327.1 - 1.7e-06 27.3 3.4 1.7e-06 27.3 2.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.2 EAZ51327.1 - 5.2e-06 26.7 5.4 5.4e-05 23.4 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Rad17 PF03215.10 EAZ51327.1 - 1.6e-05 23.8 0.0 0.1 11.2 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Fer4_6 PF12837.2 EAZ51327.1 - 3.5e-05 23.4 2.5 3.5e-05 23.4 1.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.1 EAZ51327.1 - 3.5e-05 23.2 0.4 0.038 13.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Miro PF08477.8 EAZ51327.1 - 7.4e-05 23.2 0.2 0.014 15.8 0.0 3.1 3 0 0 3 3 3 1 Miro-like protein DUF258 PF03193.11 EAZ51327.1 - 0.00013 21.1 3.0 0.11 11.6 0.0 2.9 3 0 0 3 3 2 2 Protein of unknown function, DUF258 VirE PF05272.6 EAZ51327.1 - 0.00027 20.4 0.0 0.77 9.1 0.0 2.4 2 0 0 2 2 2 2 Virulence-associated protein E AAA_18 PF13238.1 EAZ51327.1 - 0.00059 20.1 3.3 0.033 14.4 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA PF00004.24 EAZ51327.1 - 0.00082 19.5 0.1 0.42 10.8 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EAZ51327.1 - 0.00089 19.4 0.1 1.5 9.0 0.0 2.9 3 0 0 3 3 2 1 RNA helicase Fer4_9 PF13187.1 EAZ51327.1 - 0.0011 19.2 1.9 0.0011 19.2 1.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain NACHT PF05729.7 EAZ51327.1 - 0.0011 18.6 0.7 0.3 10.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain SbcCD_C PF13558.1 EAZ51327.1 - 0.0013 18.5 0.0 0.83 9.6 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EAZ51327.1 - 0.0014 19.4 3.8 1.1 10.1 0.1 3.5 4 2 0 4 4 2 1 AAA domain SRP54 PF00448.17 EAZ51327.1 - 0.0014 18.0 0.3 0.17 11.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_23 PF13476.1 EAZ51327.1 - 0.0017 18.7 3.0 0.041 14.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.15 EAZ51327.1 - 0.002 16.9 0.0 1.3 7.6 0.0 2.9 2 1 1 3 3 3 1 G-protein alpha subunit Fer4_2 PF12797.2 EAZ51327.1 - 0.0026 17.5 2.4 0.0026 17.5 1.7 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain MobB PF03205.9 EAZ51327.1 - 0.0031 17.2 0.1 0.4 10.3 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_16 PF13484.1 EAZ51327.1 - 0.0031 18.1 3.8 0.0037 17.9 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 EAZ51327.1 - 0.0042 16.8 1.9 0.0042 16.8 1.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_33 PF13671.1 EAZ51327.1 - 0.0063 16.4 0.0 0.3 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EAZ51327.1 - 0.0074 16.1 0.4 0.86 9.5 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAZ51327.1 - 0.011 15.8 0.1 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Fer4_21 PF14697.1 EAZ51327.1 - 0.011 15.5 12.3 0.033 14.0 8.6 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Zeta_toxin PF06414.7 EAZ51327.1 - 0.013 14.5 0.0 0.071 12.1 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 EAZ51327.1 - 0.021 14.8 0.5 6.3 6.7 0.0 2.6 3 1 0 3 3 2 0 AAA ATPase domain PduV-EutP PF10662.4 EAZ51327.1 - 0.024 14.0 0.2 0.64 9.4 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EAZ51327.1 - 0.029 14.3 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_3 PF12798.2 EAZ51327.1 - 0.029 14.9 4.5 0.029 14.9 3.1 2.5 2 1 0 2 2 1 0 4Fe-4S binding domain NB-ARC PF00931.17 EAZ51327.1 - 0.031 13.1 0.6 5.4 5.7 0.1 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_5 PF07728.9 EAZ51327.1 - 0.034 13.8 0.4 12 5.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 EAZ51327.1 - 0.037 12.8 0.4 1.4 7.6 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Fer4_8 PF13183.1 EAZ51327.1 - 0.042 13.8 1.1 0.042 13.8 0.7 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_25 PF13481.1 EAZ51327.1 - 0.045 13.1 0.0 4.8 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EAZ51327.1 - 0.052 13.1 0.1 0.5 9.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EAZ51327.1 - 0.053 13.2 0.0 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Fer4_4 PF12800.2 EAZ51327.1 - 0.098 13.0 14.2 0.28 11.6 2.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain MMR_HSR1 PF01926.18 EAZ51327.1 - 0.14 12.0 0.2 22 5.0 0.0 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_13 PF13166.1 EAZ51327.1 - 0.34 9.3 0.0 0.34 9.3 0.0 2.5 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.10 EAZ51327.1 - 2.7 7.6 4.8 35 4.0 0.0 3.7 6 0 0 6 6 2 0 NTPase Fer4_18 PF13746.1 EAZ51327.1 - 3 8.3 9.7 0.22 11.9 2.1 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ACBP PF00887.14 EAZ51328.1 - 4.7e-18 64.6 1.0 8.2e-18 63.8 0.7 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank PF00023.25 EAZ51328.1 - 1.4e-17 62.4 0.4 4.1e-08 32.6 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EAZ51328.1 - 2.1e-17 63.2 0.0 3.5e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAZ51328.1 - 7.9e-17 60.9 0.1 7.9e-10 38.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAZ51328.1 - 9.3e-14 51.5 0.7 2.6e-08 34.1 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAZ51328.1 - 3.6e-10 39.0 0.1 0.00071 19.5 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat BEX PF04538.7 EAZ51329.1 - 0.45 10.7 3.3 1.1 9.4 2.3 1.7 1 1 0 1 1 1 0 Brain expressed X-linked like family Snf7 PF03357.16 EAZ51329.1 - 1.2 8.4 17.0 2.3 7.6 11.8 1.5 1 1 0 1 1 1 0 Snf7 DUF2228 PF10228.4 EAZ51329.1 - 2.3 7.7 5.5 1.8 8.0 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2228) Ist1 PF03398.9 EAZ51329.1 - 2.5 7.4 8.3 1.1 8.6 3.6 1.8 2 0 0 2 2 2 0 Regulator of Vps4 activity in the MVB pathway DUF972 PF06156.8 EAZ51329.1 - 6.5 7.1 10.0 1.3 9.4 0.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SNF2_N PF00176.18 EAZ51330.1 - 3.1e-58 196.9 2.1 3.1e-58 196.9 1.5 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAZ51330.1 - 3.7e-12 45.9 0.0 4.3e-10 39.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAZ51330.1 - 4.8e-10 39.5 0.0 4.8e-10 39.5 0.0 3.4 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EAZ51330.1 - 9.8e-10 38.1 0.0 3.1e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 EAZ51330.1 - 9.5e-06 25.1 2.5 0.00028 20.3 0.3 3.1 2 0 0 2 2 2 1 DEAD_2 SR-25 PF10500.4 EAZ51330.1 - 0.0018 17.7 2.9 0.0018 17.7 2.0 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF1796 PF08795.5 EAZ51330.1 - 0.077 12.6 4.4 3.2 7.3 0.1 3.4 2 1 1 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) AAA_11 PF13086.1 EAZ51330.1 - 1.4 8.4 21.8 5.3 6.5 5.4 3.5 1 1 1 2 2 2 0 AAA domain Mre11_DNA_bind PF04152.9 EAZ51331.1 - 1.8e-34 119.0 2.6 1.8e-34 119.0 1.8 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EAZ51331.1 - 3.5e-10 39.6 2.0 6.6e-10 38.7 1.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.20 EAZ51332.1 - 3e-67 226.5 0.1 4e-67 226.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51332.1 - 2e-45 154.8 0.0 3.3e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 EAZ51333.1 - 1.2e-39 132.8 12.8 2.5e-07 30.3 0.5 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EAZ51333.1 - 1.2e-05 25.0 5.2 0.019 14.6 0.1 3.4 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EAZ51333.1 - 0.081 12.3 0.0 1.5 8.2 0.0 2.5 1 1 0 1 1 1 0 PQQ-like domain Longin PF13774.1 EAZ51334.1 - 6.7e-27 92.8 0.1 1.1e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EAZ51334.1 - 8.8e-17 60.4 1.2 1.5e-16 59.7 0.8 1.4 1 0 0 1 1 1 1 Synaptobrevin zf-RING_2 PF13639.1 EAZ51335.1 - 5.3e-13 48.5 7.1 1.1e-12 47.5 4.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAZ51335.1 - 1.1e-07 31.8 4.2 2.4e-07 30.7 2.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EAZ51335.1 - 9e-07 28.5 5.2 1.8e-06 27.5 3.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EAZ51335.1 - 3.4e-06 26.6 6.3 7.2e-06 25.5 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAZ51335.1 - 4.2e-06 26.3 3.4 7.8e-06 25.4 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAZ51335.1 - 1e-05 25.4 7.4 1e-05 25.4 5.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EAZ51335.1 - 0.0011 18.7 2.6 0.0023 17.7 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 EAZ51335.1 - 0.0087 15.7 1.6 0.0087 15.7 1.1 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 RINGv PF12906.2 EAZ51335.1 - 0.035 14.1 6.8 0.081 12.9 4.7 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EAZ51335.1 - 0.064 12.9 5.0 0.2 11.4 3.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 EAZ51335.1 - 0.092 12.4 6.0 0.22 11.2 4.1 1.7 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EAZ51335.1 - 0.15 12.0 5.4 0.52 10.2 3.7 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EAZ51335.1 - 1.1 9.1 8.4 2.1 8.3 5.0 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 EAZ51335.1 - 4 7.5 6.4 8.1 6.5 4.4 1.6 1 0 0 1 1 1 0 RING-like domain Thg1 PF04446.7 EAZ51336.1 - 1.7e-46 157.1 0.1 2.7e-46 156.5 0.1 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 EAZ51336.1 - 3e-43 146.3 1.8 6e-43 145.3 1.2 1.5 1 1 0 1 1 1 1 Thg1 C terminal domain Ras PF00071.17 EAZ51337.1 - 8.1e-62 207.3 0.2 9.3e-62 207.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAZ51337.1 - 1.3e-17 64.4 0.0 2.2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAZ51337.1 - 9.9e-14 50.9 0.1 1.3e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EAZ51337.1 - 9.1e-05 22.3 0.0 0.00014 21.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAZ51337.1 - 0.00016 21.1 0.1 0.0012 18.2 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EAZ51337.1 - 0.0036 17.1 0.1 0.0086 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EAZ51337.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EAZ51337.1 - 0.045 13.0 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B DNA_pol_E_B PF04042.11 EAZ51337.1 - 0.046 12.9 0.0 0.058 12.6 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B SLS PF14611.1 EAZ51337.1 - 0.087 12.2 0.1 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Alg6_Alg8 PF03155.10 EAZ51338.1 - 1.1e-32 113.5 43.5 1.3e-32 113.2 30.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WD40 PF00400.27 EAZ51339.1 - 2.2e-41 138.2 34.9 1.3e-09 37.5 0.5 7.6 6 1 0 7 7 7 7 WD domain, G-beta repeat Asp PF00026.18 EAZ51340.1 - 6.4e-16 58.4 0.3 1.5e-15 57.2 0.2 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EAZ51340.1 - 4.2e-12 45.9 0.0 6.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EAZ51340.1 - 6.6e-09 35.9 0.2 2.2e-08 34.2 0.1 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal DnaJ PF00226.26 EAZ51341.1 - 6.6e-16 57.8 0.0 1.4e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain LAGLIDADG_1 PF00961.14 EAZ51341.1 - 0.016 15.7 1.7 0.021 15.3 0.6 1.7 1 1 0 1 1 1 0 LAGLIDADG endonuclease Multi-haem_cyto PF13447.1 EAZ51341.1 - 0.057 12.4 0.2 0.077 12.0 0.2 1.2 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH La PF05383.12 EAZ51342.1 - 3.8e-14 52.2 1.0 1.1e-13 50.7 0.7 1.8 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 EAZ51342.1 - 0.023 14.6 0.2 0.066 13.1 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAZ51342.1 - 0.074 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 EAZ51343.1 - 3.6e-42 144.0 0.2 4.8e-42 143.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PTPA PF03095.10 EAZ51344.1 - 7.9e-102 340.4 0.9 8.9e-102 340.2 0.6 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Actin PF00022.14 EAZ51345.1 - 7.3e-54 182.6 0.0 8.5e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EAZ51345.1 - 0.00013 20.6 0.9 0.057 12.0 0.1 2.5 2 0 0 2 2 2 2 MreB/Mbl protein Proteasome PF00227.21 EAZ51346.1 - 9.6e-36 122.8 0.4 1.2e-35 122.5 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L13 PF00572.13 EAZ51346.1 - 0.0046 17.0 0.6 0.09 12.8 0.0 2.8 2 2 1 3 3 3 1 Ribosomal protein L13 Sec34 PF04136.10 EAZ51346.1 - 0.022 14.4 0.1 0.041 13.5 0.1 1.4 1 0 0 1 1 1 0 Sec34-like family OB_NTP_bind PF07717.11 EAZ51347.1 - 1.3e-25 89.4 0.0 3.4e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EAZ51347.1 - 1.6e-25 89.0 0.0 4.5e-25 87.6 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EAZ51347.1 - 5.8e-11 42.1 0.0 1.4e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EAZ51347.1 - 0.00029 21.0 0.1 0.00098 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EAZ51347.1 - 0.0003 19.8 0.0 0.00057 18.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.24 EAZ51347.1 - 0.00069 19.1 0.0 0.0021 17.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 EAZ51347.1 - 0.005 16.5 0.2 0.015 14.9 0.1 1.9 1 1 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EAZ51347.1 - 0.041 13.7 1.8 2 8.2 0.0 3.1 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit Glug PF07581.7 EAZ51347.1 - 0.056 13.6 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 The GLUG motif MobB PF03205.9 EAZ51347.1 - 0.096 12.3 0.1 0.76 9.4 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EAZ51347.1 - 0.099 12.1 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Flavi_DEAD PF07652.9 EAZ51347.1 - 0.11 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain Ank_2 PF12796.2 EAZ51348.1 - 7.5e-32 109.5 5.8 3.1e-12 46.6 0.1 4.6 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAZ51348.1 - 5.7e-19 68.1 0.4 1.9e-05 25.0 0.1 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EAZ51348.1 - 6.7e-17 60.3 0.0 0.00021 20.9 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EAZ51348.1 - 1.5e-16 58.7 0.4 0.00021 21.2 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 EAZ51348.1 - 6.5e-16 57.9 0.1 0.00067 19.8 0.0 5.6 3 2 3 6 6 6 2 Ankyrin repeats (many copies) TPR_11 PF13414.1 EAZ51348.1 - 1.3e-12 47.1 0.1 3.7e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EAZ51348.1 - 6.1e-05 22.4 0.0 0.018 14.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAZ51348.1 - 0.0001 21.9 0.0 0.29 11.1 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat LSM PF01423.17 EAZ51349.1 - 3.6e-17 61.6 0.1 5.5e-17 61.0 0.1 1.3 1 0 0 1 1 1 1 LSM domain Ufm1 PF03671.9 EAZ51350.1 - 1.4e-15 56.7 0.1 2e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Pkinase PF00069.20 EAZ51351.1 - 1.3e-45 155.5 0.2 8.5e-45 152.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51351.1 - 5.6e-31 107.5 0.0 1.7e-30 105.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51351.1 - 8.9e-07 28.1 0.0 1.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAZ51351.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ubie_methyltran PF01209.13 EAZ51352.1 - 1.8e-58 197.4 0.1 2.3e-58 197.0 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EAZ51352.1 - 6.1e-11 42.6 0.0 1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAZ51352.1 - 6.7e-11 42.0 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAZ51352.1 - 2.2e-10 40.8 0.0 5.7e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAZ51352.1 - 1.9e-09 37.8 0.0 3.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAZ51352.1 - 2.2e-08 33.9 0.0 4.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAZ51352.1 - 3.3e-05 24.4 0.0 8.3e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain GSH-S_ATP PF02955.11 EAZ51352.1 - 0.03 13.4 0.2 0.062 12.4 0.2 1.4 1 1 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Methyltransf_2 PF00891.13 EAZ51352.1 - 0.034 13.3 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF3577 PF12101.3 EAZ51352.1 - 0.039 13.8 0.5 0.21 11.4 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3577) DREV PF05219.7 EAZ51352.1 - 0.074 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_8 PF05148.10 EAZ51352.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Hypothetical methyltransferase LSM PF01423.17 EAZ51353.1 - 9e-21 73.2 0.7 1.1e-20 72.8 0.5 1.1 1 0 0 1 1 1 1 LSM domain XAP5 PF04921.9 EAZ51355.1 - 2.6e-27 95.9 7.2 3.5e-27 95.5 5.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator MinE PF03776.9 EAZ51355.1 - 0.078 12.5 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE DUF3213 PF11491.3 EAZ51355.1 - 0.76 9.6 6.9 0.87 9.4 2.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3213) Methyltransf_12 PF08242.7 EAZ51356.1 - 0.009 16.4 3.1 0.088 13.2 0.1 3.4 3 0 0 3 3 3 1 Methyltransferase domain NUC153 PF08159.7 EAZ51356.1 - 0.021 14.4 4.6 0.06 12.9 3.2 1.8 1 0 0 1 1 1 0 NUC153 domain Anophelin PF10731.4 EAZ51356.1 - 3.9 7.6 5.7 11 6.2 0.6 3.2 2 1 0 2 2 2 0 Thrombin inhibitor from mosquito Abhydrolase_2 PF02230.11 EAZ51357.1 - 4e-32 111.4 1.5 4e-32 111.4 1.1 2.6 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EAZ51357.1 - 2.4e-06 27.3 0.0 7e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EAZ51357.1 - 9.6e-05 21.9 0.0 0.00029 20.3 0.0 1.8 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EAZ51357.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold SR-25 PF10500.4 EAZ51358.1 - 0.078 12.4 0.0 0.078 12.4 0.0 3.1 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein FHA PF00498.21 EAZ51359.1 - 2.3e-15 56.4 1.1 1.5e-14 53.8 0.2 2.3 2 0 0 2 2 2 1 FHA domain Asp PF00026.18 EAZ51360.1 - 4.9e-20 72.0 3.9 2.4e-12 46.7 0.6 3.7 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.1 EAZ51360.1 - 6e-16 58.4 0.2 1.9e-08 33.9 0.0 2.8 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EAZ51360.1 - 1.7e-11 44.3 1.5 1.7e-11 44.3 1.1 2.7 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal dUTPase PF00692.14 EAZ51361.1 - 3.6e-08 32.9 0.0 2.3e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 dUTPase SpoU_methylase PF00588.14 EAZ51362.1 - 1.4e-27 96.3 0.0 1.9e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family IncA PF04156.9 EAZ51363.1 - 0.0039 16.8 18.0 0.0039 16.8 12.5 12.1 7 2 6 13 13 13 8 IncA protein Reo_sigmaC PF04582.7 EAZ51363.1 - 0.0049 16.0 0.5 0.0049 16.0 0.4 9.6 5 1 2 10 10 10 5 Reovirus sigma C capsid protein Dynein_light PF01221.13 EAZ51364.1 - 2.2e-44 149.3 1.2 2.4e-44 149.2 0.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 SpoIIIAH PF12685.2 EAZ51364.1 - 0.59 9.6 2.5 0.68 9.3 1.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein EF-hand_1 PF00036.27 EAZ51365.1 - 2e-38 126.7 12.0 5.2e-09 34.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EAZ51365.1 - 2.9e-34 117.0 7.0 2.1e-18 66.1 1.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EAZ51365.1 - 6.6e-30 102.5 13.3 5.9e-16 57.8 0.7 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EAZ51365.1 - 7.9e-29 96.9 6.9 2.4e-09 36.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EAZ51365.1 - 3.6e-24 82.9 8.1 1.3e-06 27.4 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EAZ51365.1 - 4.1e-12 45.8 0.1 3.1e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EAZ51365.1 - 3.5e-08 33.1 0.5 0.0014 18.3 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EAZ51365.1 - 1.4e-07 31.5 0.0 0.0046 16.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EAZ51365.1 - 2e-05 24.0 0.0 0.016 14.7 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EAZ51365.1 - 0.00015 21.6 0.9 0.00085 19.2 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.8 EAZ51365.1 - 0.0014 18.2 0.1 0.18 11.3 0.0 2.5 1 1 0 2 2 2 1 Caleosin related protein TerB PF05099.8 EAZ51365.1 - 0.0026 17.5 0.2 0.96 9.1 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB YqeY PF09424.5 EAZ51365.1 - 0.016 15.0 0.1 0.28 11.0 0.0 2.0 1 1 1 2 2 2 0 Yqey-like protein MotA_activ PF09114.5 EAZ51365.1 - 0.028 14.1 0.1 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain DUF1103 PF06513.6 EAZ51365.1 - 0.032 13.6 0.7 0.036 13.4 0.5 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) RNA_pol_Rpb4 PF03874.11 EAZ51365.1 - 0.056 13.4 0.2 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 EF-hand_like PF09279.6 EAZ51365.1 - 0.065 13.2 0.8 0.44 10.6 0.1 2.3 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Toprim_2 PF13155.1 EAZ51365.1 - 0.094 13.0 0.4 12 6.3 0.0 2.6 1 1 1 2 2 2 0 Toprim-like LNS2 PF08235.8 EAZ51365.1 - 0.15 11.6 0.0 1.2 8.7 0.0 1.9 1 1 1 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) SapB_1 PF05184.10 EAZ51365.1 - 0.39 10.6 1.9 24 4.8 0.0 3.0 4 0 0 4 4 4 0 Saposin-like type B, region 1 zf-C3HC4_2 PF13923.1 EAZ51366.1 - 2e-09 37.2 12.8 4.3e-09 36.2 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAZ51366.1 - 3e-09 36.3 11.8 7.8e-09 35.0 8.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAZ51366.1 - 4.8e-08 32.5 12.0 9.5e-08 31.5 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAZ51366.1 - 1e-07 31.6 12.2 2.2e-07 30.5 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EAZ51366.1 - 8e-06 25.4 13.3 1.6e-05 24.5 9.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EAZ51366.1 - 0.00015 21.4 7.6 0.0006 19.4 5.3 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EAZ51366.1 - 0.0012 18.9 4.5 0.0012 18.9 3.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EAZ51366.1 - 0.0012 18.5 6.0 0.0027 17.4 4.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DUF4200 PF13863.1 EAZ51366.1 - 0.0017 18.3 0.6 0.0017 18.3 0.4 7.0 4 2 3 7 7 5 1 Domain of unknown function (DUF4200) zf-C3HC4_4 PF15227.1 EAZ51366.1 - 0.0026 17.5 9.9 0.0067 16.2 6.9 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EAZ51366.1 - 0.0041 16.6 5.5 0.0091 15.5 3.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Prp19 PF08606.6 EAZ51366.1 - 0.0042 16.7 5.1 0.026 14.2 0.0 3.6 4 0 0 4 4 4 1 Prp19/Pso4-like Synaptobrevin PF00957.16 EAZ51366.1 - 0.1 12.2 0.2 0.1 12.2 0.1 4.3 4 0 0 4 4 4 0 Synaptobrevin zf-RING_4 PF14570.1 EAZ51366.1 - 6.9 6.3 17.0 0.15 11.6 7.0 1.9 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.20 EAZ51367.1 - 2.8e-19 69.2 0.0 4.3e-19 68.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain DEAD PF00270.24 EAZ51368.1 - 8.5e-44 149.0 0.0 1.7e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAZ51368.1 - 7.7e-28 96.1 0.0 1.9e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAZ51368.1 - 0.00091 19.1 0.0 0.0021 17.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EAZ51368.1 - 0.093 11.7 0.1 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Mito_carr PF00153.22 EAZ51369.1 - 6.2e-64 211.7 1.9 5.7e-20 70.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cyt-b5 PF00173.23 EAZ51370.1 - 3.5e-14 52.3 0.1 6.7e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PLDc_2 PF13091.1 EAZ51371.1 - 3.2e-08 33.3 1.0 0.007 16.1 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EAZ51371.1 - 0.032 14.0 2.8 0.038 13.8 0.1 2.3 2 0 0 2 2 2 0 Phospholipase D Active site motif zf-C2H2 PF00096.21 EAZ51372.1 - 5.2e-26 89.3 49.9 2.4e-05 24.4 2.9 7.3 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAZ51372.1 - 2.9e-23 80.4 47.5 0.0007 19.7 0.6 7.6 7 0 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAZ51372.1 - 2.4e-13 49.6 53.4 2.3e-05 24.4 1.7 9.1 9 1 0 9 9 9 4 Zinc-finger double domain zf-C2H2_6 PF13912.1 EAZ51372.1 - 4.6e-08 32.6 18.5 0.062 13.2 0.1 6.0 6 0 0 6 6 6 3 C2H2-type zinc finger zf-met PF12874.2 EAZ51372.1 - 0.0046 17.1 25.6 0.28 11.4 0.1 7.6 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-met2 PF12907.2 EAZ51372.1 - 1.3 9.0 0.0 1.3 9.0 0.0 5.2 6 0 0 6 6 6 0 Zinc-binding DUF629 PF04780.7 EAZ51372.1 - 1.4 7.3 21.8 2.8 6.3 0.5 5.4 2 2 4 6 6 6 0 Protein of unknown function (DUF629) DUF2321 PF10083.4 EAZ51372.1 - 2 7.8 7.9 8.2 5.9 0.1 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2_jaz PF12171.3 EAZ51372.1 - 4.9 7.4 26.7 10 6.4 0.4 7.7 7 1 1 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EAZ51372.1 - 6.7 6.8 27.3 27 4.9 0.1 6.3 1 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) ATP-synt_ab PF00006.20 EAZ51373.1 - 4.2e-65 219.2 0.0 7.9e-65 218.3 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 EAZ51373.1 - 1e-22 80.0 0.4 2.4e-22 78.9 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 EAZ51373.1 - 1.8e-14 54.1 0.0 4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain KaiC PF06745.8 EAZ51373.1 - 0.0023 17.0 1.7 0.0029 16.7 0.4 1.7 2 0 0 2 2 2 1 KaiC NB-ARC PF00931.17 EAZ51373.1 - 0.0064 15.3 0.1 0.012 14.4 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 EAZ51373.1 - 0.0073 16.0 0.1 0.017 14.8 0.1 1.5 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 EAZ51373.1 - 0.028 14.6 0.1 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EAZ51373.1 - 0.062 12.4 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAZ51373.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EAZ51373.1 - 1.1 9.5 4.2 1.5 9.1 0.2 2.9 3 1 1 4 4 4 0 ABC transporter ThiF PF00899.16 EAZ51374.1 - 3.7e-35 120.7 0.6 3.7e-35 120.7 0.4 2.0 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EAZ51374.1 - 7.1e-25 86.3 0.3 2.2e-24 84.7 0.0 2.0 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EAZ51374.1 - 4.3e-17 61.2 1.0 8e-17 60.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EAZ51374.1 - 3.4e-10 39.8 0.0 1e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EAZ51374.1 - 0.0017 18.5 0.3 0.0075 16.5 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EAZ51374.1 - 0.0025 17.8 0.0 0.0059 16.7 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EAZ51374.1 - 0.014 14.4 0.4 0.039 12.9 0.3 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase Pyr_redox PF00070.22 EAZ51374.1 - 0.034 14.5 0.1 0.09 13.1 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAZ51374.1 - 0.39 9.5 0.5 0.59 8.9 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pkinase PF00069.20 EAZ51375.1 - 1.3e-46 158.8 0.0 3.2e-46 157.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51375.1 - 4e-18 65.4 0.0 1.3e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EAZ51375.1 - 0.00099 18.2 0.0 0.093 11.7 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family dCMP_cyt_deam_1 PF00383.17 EAZ51376.1 - 1.1e-12 47.4 2.4 2.5e-12 46.3 1.6 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EAZ51376.1 - 0.077 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase Pro_isomerase PF00160.16 EAZ51377.1 - 6.6e-45 153.0 0.0 7.5e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CTDII PF01556.13 EAZ51378.1 - 4e-29 100.3 3.0 2.3e-23 81.8 0.2 2.8 2 1 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EAZ51378.1 - 5.7e-27 93.2 3.7 9e-27 92.5 2.6 1.3 1 0 0 1 1 1 1 DnaJ domain Inositol_P PF00459.20 EAZ51379.1 - 3.4e-39 134.7 0.0 4.6e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 EAZ51379.1 - 0.0025 16.6 0.0 0.0037 16.1 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase zf-C3HC4 PF00097.20 EAZ51380.1 - 1.8e-09 37.0 9.4 2.8e-09 36.4 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAZ51380.1 - 2.1e-09 37.2 11.9 3.2e-09 36.6 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAZ51380.1 - 9e-09 34.9 8.7 1.4e-08 34.3 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAZ51380.1 - 1.7e-08 34.0 6.3 2.5e-08 33.4 4.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAZ51380.1 - 2.7e-08 33.5 10.9 4.1e-08 32.9 7.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EAZ51380.1 - 4.3e-06 26.3 3.9 8.8e-05 22.1 0.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAZ51380.1 - 0.00014 21.6 9.1 0.00029 20.6 6.4 1.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.7 EAZ51380.1 - 0.0039 16.4 0.6 0.0096 15.1 0.4 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-rbx1 PF12678.2 EAZ51380.1 - 0.038 14.1 8.3 0.063 13.3 5.7 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 EAZ51380.1 - 0.12 11.9 4.2 0.21 11.1 2.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EAZ51380.1 - 0.13 12.0 5.8 0.23 11.2 4.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EAZ51380.1 - 0.35 10.4 7.0 0.65 9.5 4.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.6 EAZ51380.1 - 1.9 8.2 8.9 3.5 7.3 6.2 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Pkinase PF00069.20 EAZ51381.1 - 1.1e-52 178.8 0.7 1.1e-30 106.6 0.6 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51381.1 - 4e-24 85.0 0.1 4.2e-16 58.7 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EAZ51381.1 - 7.6e-08 32.3 0.1 0.0001 22.1 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EAZ51381.1 - 4.3e-06 25.8 0.1 0.00013 21.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EAZ51381.1 - 0.00085 18.4 0.0 0.0016 17.5 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_11 PF13414.1 EAZ51382.1 - 4.7e-51 170.3 17.1 1.5e-19 69.3 1.1 4.2 4 0 0 4 4 4 4 TPR repeat TPR_1 PF00515.23 EAZ51382.1 - 4.9e-44 146.1 28.0 2e-09 36.6 0.7 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 EAZ51382.1 - 1.6e-36 121.2 21.8 9.7e-07 28.2 0.1 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 EAZ51382.1 - 3.8e-22 78.0 9.7 1.3e-11 44.2 0.1 4.3 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 EAZ51382.1 - 5.4e-20 71.5 0.4 2.8e-08 34.2 0.1 4.5 2 2 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EAZ51382.1 - 7.6e-19 66.2 12.4 0.00012 22.0 0.0 6.8 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EAZ51382.1 - 2.2e-17 61.4 27.7 0.00041 19.9 0.1 6.4 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.1 EAZ51382.1 - 4.3e-17 62.2 5.4 0.00065 19.9 0.2 4.6 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 EAZ51382.1 - 7.3e-13 47.9 0.2 1.2 10.0 0.0 6.9 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EAZ51382.1 - 8.9e-12 44.7 0.3 0.0039 17.0 0.1 4.6 2 1 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EAZ51382.1 - 1.6e-09 37.7 16.0 4.6e-06 26.6 1.7 3.7 1 1 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EAZ51382.1 - 1.4e-07 31.2 0.4 0.48 10.4 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAZ51382.1 - 2.1e-05 23.9 10.1 0.0085 15.8 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAZ51382.1 - 7.3e-05 22.5 17.6 0.22 11.4 0.2 6.3 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EAZ51382.1 - 0.00014 22.1 12.9 0.63 10.6 0.2 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat XPC-binding PF09280.6 EAZ51382.1 - 0.023 14.1 1.8 0.071 12.5 1.2 1.9 1 0 0 1 1 1 0 XPC-binding domain TFIID_90kDa PF04494.10 EAZ51382.1 - 0.028 14.4 1.0 0.37 10.8 0.0 2.5 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit TPR_3 PF07720.7 EAZ51382.1 - 0.037 13.8 0.4 0.037 13.8 0.2 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat KapB PF08810.5 EAZ51382.1 - 0.067 13.2 3.8 0.15 12.0 1.0 2.5 2 0 0 2 2 2 0 Kinase associated protein B PPR PF01535.15 EAZ51382.1 - 0.097 12.6 0.3 0.097 12.6 0.2 3.0 3 0 0 3 3 3 0 PPR repeat Coatomer_E PF04733.9 EAZ51382.1 - 0.1 11.7 10.1 5.1 6.2 0.0 4.2 1 1 3 4 4 4 0 Coatomer epsilon subunit Mad3_BUB1_I PF08311.7 EAZ51382.1 - 0.13 12.0 7.9 0.096 12.4 0.7 3.2 3 1 0 3 3 3 0 Mad3/BUB1 homology region 1 Seryl_tRNA_N PF02403.17 EAZ51382.1 - 0.74 9.8 7.6 0.24 11.4 2.2 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mgr1 PF08602.5 EAZ51382.1 - 1.6 7.6 6.7 0.46 9.4 1.9 1.8 1 1 1 2 2 2 0 Mgr1-like, i-AAA protease complex subunit WD40 PF00400.27 EAZ51383.1 - 8.6e-61 199.8 35.7 3.8e-12 45.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EAZ51383.1 - 0.00019 19.7 6.8 0.3 9.1 0.1 3.7 1 1 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EAZ51383.1 - 0.00094 19.3 1.1 0.98 9.7 0.0 4.0 3 1 0 3 3 3 1 PQQ-like domain Nucleoporin_N PF08801.6 EAZ51383.1 - 0.019 13.7 1.8 11 4.5 0.1 3.4 2 2 1 3 3 3 0 Nup133 N terminal like VID27 PF08553.5 EAZ51383.1 - 0.042 12.0 0.0 0.063 11.4 0.0 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Pkinase PF00069.20 EAZ51384.1 - 9.4e-13 47.8 0.0 1.1e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51384.1 - 7.7e-07 28.4 0.0 8.5e-07 28.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51384.1 - 0.0028 16.6 0.0 0.0032 16.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAZ51384.1 - 0.0061 15.6 0.0 0.0068 15.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EAZ51384.1 - 0.041 12.6 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EAZ51384.1 - 0.057 13.1 0.0 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family IncA PF04156.9 EAZ51385.1 - 0.0046 16.5 16.6 0.0046 16.5 11.5 2.0 1 1 1 2 2 2 1 IncA protein Reo_sigmaC PF04582.7 EAZ51385.1 - 0.047 12.8 0.9 0.11 11.6 0.6 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EAZ51385.1 - 0.077 11.6 24.9 0.014 14.0 14.0 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Sigma54_CBD PF04963.8 EAZ51385.1 - 0.096 12.1 4.4 1 8.7 0.8 2.9 1 1 2 3 3 3 0 Sigma-54 factor, core binding domain DUF489 PF04356.7 EAZ51385.1 - 0.18 11.3 4.9 18 4.8 3.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF489) LOH1CR12 PF10158.4 EAZ51385.1 - 0.32 10.7 5.5 0.33 10.7 0.3 3.0 1 1 3 4 4 4 0 Tumour suppressor protein DUF2951 PF11166.3 EAZ51385.1 - 0.61 9.9 26.2 0.029 14.2 2.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) COG2 PF06148.6 EAZ51385.1 - 0.62 9.9 9.3 0.065 13.1 1.2 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tfb4 PF03850.9 EAZ51385.1 - 1.8 7.7 8.1 0.38 9.9 1.1 2.0 1 1 1 2 2 2 0 Transcription factor Tfb4 DUF1664 PF07889.7 EAZ51385.1 - 2 8.2 15.5 0.065 13.0 0.7 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4140 PF13600.1 EAZ51385.1 - 4.3 7.8 6.5 1.2 9.6 0.1 3.0 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 EAZ51385.1 - 4.4 7.6 20.4 0.1 12.9 3.2 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 EAZ51385.1 - 4.7 7.3 19.8 0.089 12.9 6.6 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family CarD_CdnL_TRCF PF02559.11 EAZ51385.1 - 4.9 7.2 7.1 10 6.2 0.4 2.7 1 1 0 2 2 2 0 CarD-like/TRCF domain Laminin_II PF06009.7 EAZ51385.1 - 6.1 6.6 16.3 4.2 7.1 6.8 3.1 1 1 1 2 2 2 0 Laminin Domain II Epimerase PF01370.16 EAZ51386.1 - 2e-41 141.9 0.0 2.5e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EAZ51386.1 - 6.1e-11 41.7 0.0 1e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EAZ51386.1 - 1.1e-08 34.1 0.0 1.4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EAZ51386.1 - 4.5e-07 29.0 0.0 5.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EAZ51386.1 - 0.0017 17.2 0.1 0.021 13.7 0.1 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EAZ51386.1 - 0.006 16.6 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EAZ51386.1 - 0.0061 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EAZ51386.1 - 0.0083 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Ras PF00071.17 EAZ51387.1 - 6.5e-59 197.9 0.4 8.2e-59 197.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAZ51387.1 - 2.3e-19 70.0 0.1 7.9e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EAZ51387.1 - 4.6e-15 55.3 0.3 6.1e-15 54.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAZ51387.1 - 9.9e-08 31.6 0.0 2.8e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EAZ51387.1 - 1.3e-05 24.4 0.2 1.6e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAZ51387.1 - 8.8e-05 22.4 0.1 0.00013 21.9 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EAZ51387.1 - 0.00016 20.9 0.2 0.00056 19.1 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EAZ51387.1 - 0.0092 15.2 0.3 0.17 11.1 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B CbiA PF01656.18 EAZ51387.1 - 0.023 14.0 0.1 0.19 11.0 0.1 2.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Arch_ATPase PF01637.13 EAZ51387.1 - 0.046 13.4 2.5 0.12 12.1 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase Pkinase PF00069.20 EAZ51388.1 - 1.4e-69 234.1 0.0 2.5e-69 233.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51388.1 - 6.3e-31 107.3 0.1 2.2e-30 105.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51388.1 - 4.6e-08 32.3 0.2 3.9e-07 29.3 0.0 2.5 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 EAZ51388.1 - 0.047 12.7 0.1 0.093 11.7 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GTP_EFTU PF00009.22 EAZ51390.1 - 4.3e-46 156.7 0.0 7e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EAZ51390.1 - 1.7e-18 66.5 0.0 4.1e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EAZ51390.1 - 9.9e-07 28.7 0.0 5.1e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAZ51390.1 - 0.00059 19.7 0.0 0.0013 18.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNB PF00773.14 EAZ51391.1 - 4.6e-98 328.4 6.9 8e-98 327.6 4.8 1.3 1 0 0 1 1 1 1 RNB domain Rer1 PF03248.8 EAZ51392.1 - 6.6e-52 175.6 14.8 9.1e-52 175.1 10.3 1.2 1 0 0 1 1 1 1 Rer1 family 2TM PF13239.1 EAZ51392.1 - 0.24 11.4 11.0 2 8.5 0.9 2.2 2 0 0 2 2 2 0 2TM domain E1-E2_ATPase PF00122.15 EAZ51393.1 - 2.9e-21 75.5 1.1 6.7e-21 74.3 0.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EAZ51393.1 - 5.1e-09 36.8 0.0 2.3e-05 24.9 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAZ51393.1 - 8.2e-08 32.1 0.0 6.7e-07 29.1 0.0 2.5 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EAZ51393.1 - 3.5e-05 24.0 0.0 0.0025 18.0 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAZ51393.1 - 0.008 15.7 0.7 0.008 15.7 0.5 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.1 EAZ51393.1 - 0.1 11.3 0.5 0.19 10.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Trm112p PF03966.11 EAZ51394.1 - 8.9e-08 32.3 0.0 1.2e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein Bromodomain PF00439.20 EAZ51395.1 - 5.9e-23 80.6 0.7 3.7e-22 78.0 0.1 2.1 2 0 0 2 2 2 1 Bromodomain DUF1399 PF07173.7 EAZ51395.1 - 1.2 9.4 5.9 1.3 9.3 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1399) Mmp37 PF09139.6 EAZ51396.1 - 3.8e-19 68.8 0.5 4.5e-19 68.6 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Spt4 PF06093.8 EAZ51397.1 - 2.2e-30 104.3 0.3 3.5e-30 103.7 0.2 1.3 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Methyltransf_23 PF13489.1 EAZ51398.1 - 1.5e-14 54.0 0.0 4.8e-14 52.3 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAZ51398.1 - 8.7e-12 44.8 1.3 5.3e-07 29.3 0.2 2.8 2 1 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.7 EAZ51398.1 - 3.4e-09 37.0 0.0 1.8e-07 31.5 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAZ51398.1 - 2.1e-08 34.7 0.0 4.4e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAZ51398.1 - 5.1e-08 33.3 0.1 6.1e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EAZ51398.1 - 8.4e-05 22.0 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EAZ51398.1 - 0.00021 20.5 0.0 0.00028 20.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EAZ51398.1 - 0.0033 16.4 0.0 0.005 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EAZ51398.1 - 0.0051 16.8 0.0 0.0091 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAZ51398.1 - 0.0055 17.0 0.0 0.019 15.3 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 EAZ51398.1 - 0.062 12.6 0.0 8 5.7 0.0 2.3 1 1 1 2 2 2 0 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 EAZ51398.1 - 0.065 11.9 0.0 0.45 9.1 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) WD40 PF00400.27 EAZ51399.1 - 3.3e-14 52.1 2.3 4.2e-05 23.2 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EAZ51399.1 - 0.0081 14.9 0.6 0.037 12.7 0.2 2.0 1 1 1 2 2 2 1 Nup133 N terminal like Metallophos PF00149.23 EAZ51400.1 - 2.9e-35 121.4 1.4 4.3e-35 120.9 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EAZ51400.1 - 1.4e-18 66.2 3.2 3.3e-13 49.0 0.6 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EAZ51400.1 - 2.3e-13 49.1 5.2 0.00021 20.7 0.2 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat PPP5 PF08321.7 EAZ51400.1 - 1.8e-11 43.8 0.1 0.00027 20.8 0.0 2.7 2 0 0 2 2 2 2 PPP5 TPR repeat region TPR_2 PF07719.12 EAZ51400.1 - 2.3e-11 42.7 0.6 0.012 15.4 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAZ51400.1 - 0.0012 18.6 0.9 0.019 14.8 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAZ51400.1 - 0.0018 17.8 5.3 2.6 8.0 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAZ51400.1 - 0.0031 17.5 0.5 0.086 13.0 0.0 3.2 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EAZ51400.1 - 0.005 16.6 0.0 1.1 9.1 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.1 EAZ51400.1 - 0.011 14.9 0.4 0.017 14.2 0.3 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 EAZ51400.1 - 0.013 15.6 5.9 0.13 12.4 4.1 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SusD-like_3 PF14322.1 EAZ51400.1 - 0.11 12.5 1.7 0.21 11.6 1.2 1.4 1 0 0 1 1 1 0 Starch-binding associating with outer membrane TPR_7 PF13176.1 EAZ51400.1 - 0.11 12.3 0.1 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAZ51400.1 - 0.26 11.8 1.4 9.4 6.9 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SHS2_Rpb7-N PF03876.12 EAZ51401.1 - 3.8e-13 49.3 0.0 8e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.7 EAZ51401.1 - 2.3e-06 27.7 0.0 3.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 S1 PF00575.18 EAZ51401.1 - 5.6e-06 26.3 0.5 1.3e-05 25.1 0.3 1.7 2 1 0 2 2 2 1 S1 RNA binding domain Ribosomal_L13e PF01294.13 EAZ51402.1 - 6.9e-54 182.0 4.6 8.3e-54 181.7 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e RasGAP_C PF03836.10 EAZ51402.1 - 0.083 12.5 0.6 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 RasGAP C-terminus Rep_fac_C PF08542.6 EAZ51404.1 - 5.2e-18 64.8 0.0 1.4e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EAZ51404.1 - 6.5e-09 35.6 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EAZ51404.1 - 0.0033 17.6 0.0 0.0073 16.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EAZ51404.1 - 0.035 12.7 0.0 0.082 11.5 0.0 1.6 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EAZ51404.1 - 0.08 12.9 0.0 0.19 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.20 EAZ51405.1 - 5.3e-73 245.3 0.0 6.6e-73 245.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51405.1 - 1.4e-40 138.9 0.0 1.9e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51405.1 - 2.4e-05 23.4 0.0 3.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAZ51405.1 - 0.02 14.6 0.1 2 8.0 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EAZ51405.1 - 0.03 13.6 0.1 0.54 9.5 0.0 2.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL DnaJ PF00226.26 EAZ51406.1 - 4.3e-26 90.4 1.0 8.6e-26 89.4 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.15 EAZ51406.1 - 3.8e-15 55.4 0.1 3.1e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.16 EAZ51406.1 - 0.0043 16.7 0.0 0.031 13.9 0.0 2.3 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EAZ51406.1 - 0.0044 17.1 2.7 0.29 11.2 0.0 3.5 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EAZ51406.1 - 0.032 14.4 0.1 0.087 13.0 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EAZ51406.1 - 0.034 13.9 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain Dynamin_M PF01031.15 EAZ51407.1 - 3.7e-93 311.5 0.2 6.9e-93 310.6 0.1 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EAZ51407.1 - 1.9e-49 167.7 1.4 7.6e-49 165.7 0.1 2.4 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EAZ51407.1 - 4.3e-28 97.0 2.4 1.1e-27 95.7 1.7 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EAZ51407.1 - 0.00015 21.6 2.9 0.00057 19.8 0.2 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EAZ51407.1 - 0.0012 19.3 0.0 0.0037 17.7 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein zf-C4H2 PF10146.4 EAZ51407.1 - 0.44 10.5 3.3 0.4 10.6 0.6 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein Arf PF00025.16 EAZ51408.1 - 2.1e-77 258.3 0.2 2.3e-77 258.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EAZ51408.1 - 7.7e-14 51.3 0.0 8.5e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EAZ51408.1 - 4.5e-13 48.8 0.0 5.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EAZ51408.1 - 5.9e-11 41.6 1.2 7e-08 31.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EAZ51408.1 - 6.7e-10 38.5 0.0 7.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EAZ51408.1 - 1.5e-09 38.3 0.0 2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EAZ51408.1 - 2.6e-06 27.3 0.1 4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAZ51408.1 - 0.0031 16.9 0.1 0.024 14.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EAZ51408.1 - 0.0065 15.5 0.1 0.012 14.7 0.1 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase cobW PF02492.14 EAZ51408.1 - 0.031 13.7 0.1 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EAZ51408.1 - 0.035 13.9 0.2 0.083 12.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain PDCD2_C PF04194.8 EAZ51409.1 - 2.7e-42 144.1 1.2 4.4e-39 133.6 0.1 2.2 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain CpXC PF14353.1 EAZ51409.1 - 0.39 10.6 4.8 0.15 12.0 0.8 2.2 2 0 0 2 2 2 0 CpXC protein Peptidase_S8 PF00082.17 EAZ51410.1 - 2e-28 99.3 0.2 2.7e-28 98.9 0.1 1.1 1 0 0 1 1 1 1 Subtilase family BOP1NT PF08145.7 EAZ51411.1 - 6.6e-74 248.9 6.1 1.1e-73 248.1 4.2 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EAZ51411.1 - 8.6e-14 50.7 2.1 0.051 13.4 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat NIF PF03031.13 EAZ51412.1 - 3.2e-44 150.4 0.1 1.1e-43 148.6 0.1 2.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ER PF01133.12 EAZ51413.1 - 1.1e-30 105.3 1.6 1.2e-30 105.2 1.1 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary PRANC PF09372.5 EAZ51413.1 - 0.02 14.8 3.4 0.027 14.4 2.1 1.4 1 1 0 1 1 1 0 PRANC domain NRN1 PF15056.1 EAZ51413.1 - 0.14 12.1 0.3 0.59 10.1 0.2 1.9 1 1 0 1 1 1 0 Neuritin protein family DS PF01916.12 EAZ51414.1 - 7.9e-128 425.7 0.0 9.5e-128 425.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Rad51 PF08423.6 EAZ51415.1 - 5.8e-13 48.3 0.0 8.2e-07 28.1 0.0 2.1 1 1 1 2 2 2 2 Rad51 AAA_25 PF13481.1 EAZ51415.1 - 1.7e-07 30.8 0.0 2.5e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EAZ51415.1 - 5.3e-07 28.9 0.8 5.3e-05 22.4 0.0 2.3 2 1 0 2 2 2 2 KaiC AAA_24 PF13479.1 EAZ51415.1 - 0.00097 18.7 0.1 0.019 14.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 EAZ51415.1 - 0.0016 17.5 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_19 PF13245.1 EAZ51415.1 - 0.047 13.4 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Pro_isomerase PF00160.16 EAZ51416.1 - 5.9e-47 159.7 0.0 6.6e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 EAZ51416.1 - 0.047 13.5 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Rho_N PF07498.7 EAZ51417.1 - 6.5e-05 22.6 0.2 6.5e-05 22.6 0.1 2.4 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain HeH PF12949.2 EAZ51417.1 - 0.00023 20.6 0.2 0.0017 17.8 0.0 2.6 2 0 0 2 2 2 1 HeH/LEM domain SAP PF02037.22 EAZ51417.1 - 0.0027 17.1 0.2 0.0093 15.4 0.1 2.0 1 0 0 1 1 1 1 SAP domain CENP-F_leu_zip PF10473.4 EAZ51417.1 - 0.0039 17.0 26.0 0.0039 17.0 18.0 2.4 3 1 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1192 PF06698.6 EAZ51417.1 - 0.14 11.9 5.7 0.34 10.7 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Reo_sigmaC PF04582.7 EAZ51417.1 - 0.28 10.3 3.8 0.52 9.4 2.6 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF2968 PF11180.3 EAZ51417.1 - 0.65 9.3 10.1 0.12 11.7 4.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) YlqD PF11068.3 EAZ51417.1 - 0.74 9.8 22.4 0.17 11.9 0.3 3.2 1 1 2 3 3 3 0 YlqD protein NDUF_B5 PF09781.4 EAZ51417.1 - 1.3 8.3 5.1 1.6 7.9 2.7 1.8 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Shugoshin_N PF07558.6 EAZ51417.1 - 2 8.1 15.7 0.58 9.9 5.8 3.5 3 1 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Sybindin PF04099.7 EAZ51418.1 - 1.3e-41 141.6 0.1 1.4e-41 141.5 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EAZ51418.1 - 2.6e-08 33.7 0.0 2.9e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.20 EAZ51419.1 - 1.2e-60 204.9 0.4 1.6e-39 135.6 0.7 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51419.1 - 3e-28 98.5 0.1 4.6e-24 84.8 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DUF1126 PF06565.7 EAZ51419.1 - 0.08 12.4 0.4 0.17 11.3 0.3 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1126) Kdo PF06293.9 EAZ51419.1 - 0.16 11.0 0.0 0.43 9.6 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 EAZ51420.1 - 2.3e-20 73.1 0.0 6.3e-20 71.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAZ51420.1 - 1.9e-15 57.2 0.0 3.8e-15 56.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAZ51420.1 - 6.8e-10 38.9 0.0 5.2e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EAZ51420.1 - 3.5e-08 33.1 0.0 2.2e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAZ51420.1 - 1.4e-06 27.2 1.1 5.6e-06 25.2 0.8 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EAZ51420.1 - 1.6e-05 23.9 0.6 6.5e-05 21.9 0.4 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EAZ51420.1 - 0.0027 16.6 0.2 1 8.1 0.1 3.0 2 1 0 2 2 2 1 Male sterility protein Bacteriocin_IId PF09221.5 EAZ51420.1 - 0.026 14.4 0.1 12 5.8 0.0 3.3 3 0 0 3 3 3 0 Bacteriocin class IId cyclical uberolysin-like DUF1776 PF08643.5 EAZ51420.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Peptidase_C1 PF00112.18 EAZ51421.1 - 1.9e-40 139.1 7.0 2.5e-40 138.7 4.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EAZ51421.1 - 0.0019 16.8 0.3 0.0019 16.8 0.2 1.6 2 0 0 2 2 2 1 Peptidase C1-like family PIP5K PF01504.13 EAZ51421.1 - 0.086 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase RNA_pol_Rpb1_1 PF04997.7 EAZ51422.1 - 0.012 14.9 0.0 0.016 14.4 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Flavoprotein PF02441.14 EAZ51423.1 - 2.4e-45 153.3 0.1 3e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein NAD_binding_7 PF13241.1 EAZ51423.1 - 0.084 13.1 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pkinase PF00069.20 EAZ51424.1 - 6.3e-82 274.6 0.1 1e-81 273.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51424.1 - 1.6e-43 148.6 0.0 2.5e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EAZ51424.1 - 1.9e-25 86.1 10.5 7.7e-07 27.9 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EAZ51424.1 - 6e-23 80.7 7.8 1.1e-12 47.9 1.4 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EAZ51424.1 - 9.8e-20 68.9 9.1 2.7e-05 23.3 0.2 4.8 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EAZ51424.1 - 1e-19 68.5 8.8 2e-06 27.2 0.2 5.0 3 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EAZ51424.1 - 3.4e-18 64.9 12.2 0.00033 20.2 0.2 4.6 2 1 2 4 4 4 4 EF-hand domain pair Kinase-like PF14531.1 EAZ51424.1 - 6.1e-07 28.6 0.0 0.00094 18.2 0.0 2.6 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 EAZ51424.1 - 1.6e-06 27.3 0.3 4e-06 26.0 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.2 EAZ51424.1 - 3.4e-05 23.5 6.3 0.085 12.5 0.5 3.7 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EAZ51424.1 - 0.00022 21.2 0.7 0.75 9.8 0.0 2.6 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region YrbL-PhoP_reg PF10707.4 EAZ51424.1 - 0.0012 18.2 0.7 0.002 17.4 0.0 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL EF-hand_9 PF14658.1 EAZ51424.1 - 0.0015 18.3 0.4 0.025 14.4 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain Pox_ser-thr_kin PF05445.6 EAZ51424.1 - 0.0045 15.8 0.5 0.027 13.2 0.2 2.2 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EAZ51424.1 - 0.0079 15.9 0.0 0.024 14.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAZ51424.1 - 0.047 13.2 0.7 0.1 12.1 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Adenine_glyco PF03352.8 EAZ51424.1 - 0.079 12.4 0.6 0.18 11.3 0.4 1.6 1 0 0 1 1 1 0 Methyladenine glycosylase p25-alpha PF05517.7 EAZ51424.1 - 0.098 12.9 4.4 7.1 6.8 1.1 2.4 2 0 0 2 2 2 0 p25-alpha EF-hand_10 PF14788.1 EAZ51424.1 - 0.17 11.5 3.6 1 9.0 0.0 3.2 2 1 0 2 2 2 0 EF hand Rhomboid PF01694.17 EAZ51425.1 - 4.7e-31 107.7 13.7 6.2e-31 107.3 9.5 1.2 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.10 EAZ51425.1 - 5.2e-05 22.8 1.2 7.3e-05 22.3 0.9 1.3 1 0 0 1 1 1 1 Der1-like family Aminotran_5 PF00266.14 EAZ51426.1 - 1.7e-26 92.8 0.0 2.3e-18 66.0 0.0 3.1 3 0 0 3 3 3 2 Aminotransferase class-V ATP_bind_3 PF01171.15 EAZ51426.1 - 1.9e-16 60.0 0.0 4.3e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 PP-loop family SHMT PF00464.14 EAZ51426.1 - 0.00082 17.8 0.0 0.0014 17.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF1002 PF06207.6 EAZ51426.1 - 0.04 13.2 1.3 0.089 12.0 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) zf-C2H2_jaz PF12171.3 EAZ51426.1 - 2.8 8.2 6.6 0.75 10.0 1.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding EF-hand_7 PF13499.1 EAZ51428.1 - 2.3e-23 82.1 6.5 2.7e-12 46.6 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EAZ51428.1 - 1.1e-21 74.4 15.9 7.2e-09 34.3 0.7 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 EAZ51428.1 - 5.2e-20 69.4 9.1 1e-05 25.0 0.2 4.6 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EAZ51428.1 - 4.1e-17 61.5 11.1 1.1e-14 53.7 0.5 4.1 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.1 EAZ51428.1 - 1.6e-11 43.9 0.0 2.8e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EAZ51428.1 - 3.5e-10 38.7 13.7 0.00019 20.6 0.3 4.4 5 1 0 5 5 5 2 EF hand EF-hand_4 PF12763.2 EAZ51428.1 - 6.5e-06 25.8 2.5 0.036 13.7 0.6 2.5 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand RRM_3 PF08777.6 EAZ51428.1 - 0.061 13.1 2.7 0.8 9.5 0.2 2.3 1 1 1 2 2 2 0 RNA binding motif MgtE_N PF03448.12 EAZ51428.1 - 0.098 12.9 0.4 0.098 12.9 0.3 1.7 2 0 0 2 2 1 0 MgtE intracellular N domain PRESAN PF09687.5 EAZ51428.1 - 0.7 9.9 4.4 3.3 7.7 0.5 2.4 1 1 0 2 2 2 0 Plasmodium RESA N-terminal EF-hand_10 PF14788.1 EAZ51428.1 - 1.9 8.2 4.5 0.9 9.2 0.4 2.4 2 0 0 2 2 2 0 EF hand Pkinase PF00069.20 EAZ51429.1 - 2.6e-71 239.8 0.0 2.9e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51429.1 - 1.3e-34 119.4 0.0 1.6e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAZ51429.1 - 0.0059 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAZ51429.1 - 0.038 13.5 0.0 0.091 12.3 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Profilin PF00235.14 EAZ51430.1 - 4e-15 55.9 0.5 5.3e-15 55.5 0.3 1.2 1 0 0 1 1 1 1 Profilin Pox_T4_N PF04491.7 EAZ51430.1 - 0.17 11.7 1.2 17 5.3 0.0 2.8 2 1 1 3 3 3 0 Poxvirus T4 protein, N terminus Pkinase PF00069.20 EAZ51431.1 - 1.5e-37 129.1 0.0 1.7e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51431.1 - 1.1e-16 60.6 0.0 1.4e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAZ51431.1 - 6.7e-05 22.7 0.0 0.0015 18.2 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EAZ51431.1 - 0.015 14.1 0.3 0.022 13.5 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SKG6 PF08693.5 EAZ51431.1 - 0.11 11.8 0.5 0.38 10.0 0.3 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NUDIX PF00293.23 EAZ51432.1 - 3.2e-07 30.0 0.1 3.5e-07 29.9 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain UDPG_MGDP_dh_C PF03720.10 EAZ51432.1 - 0.032 14.3 0.1 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Carot_N PF09150.5 EAZ51432.1 - 0.034 13.8 0.2 0.08 12.6 0.1 1.6 1 1 1 2 2 2 0 Orange carotenoid protein, N-terminal PS_Dcarbxylase PF02666.10 EAZ51434.1 - 8e-59 198.3 0.0 1e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase UQ_con PF00179.21 EAZ51435.1 - 3.4e-47 159.3 0.0 3.9e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAZ51435.1 - 0.00064 19.4 0.0 0.0008 19.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EAZ51435.1 - 0.0069 16.0 0.1 0.012 15.2 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EAZ51435.1 - 0.024 14.5 0.1 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain RRM_1 PF00076.17 EAZ51436.1 - 1.2e-14 53.6 0.0 1.5e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAZ51436.1 - 2.1e-10 40.4 0.0 2.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAZ51436.1 - 6e-08 32.4 0.2 1.2e-07 31.4 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PDEase_I PF00233.14 EAZ51437.1 - 2.2e-54 184.7 0.0 3.9e-54 183.9 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MASE1 PF05231.9 EAZ51437.1 - 0.39 9.6 12.2 0.6 9.0 8.5 1.2 1 0 0 1 1 1 0 MASE1 DEAD PF00270.24 EAZ51438.1 - 2.6e-43 147.4 0.0 6.2e-43 146.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAZ51438.1 - 2.2e-22 78.6 0.2 7.5e-22 76.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EAZ51438.1 - 2.8e-05 23.8 5.8 7.9e-05 22.3 4.0 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain SH3BGR PF04908.10 EAZ51438.1 - 0.53 10.2 3.7 4.1 7.3 0.1 3.0 3 0 0 3 3 3 0 SH3-binding, glutamic acid-rich protein adh_short PF00106.20 EAZ51439.1 - 3.3e-21 75.9 0.0 4e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAZ51439.1 - 6e-10 39.2 0.0 7.8e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAZ51439.1 - 4.8e-06 26.3 0.0 7.8e-06 25.6 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EAZ51439.1 - 5.6e-05 22.6 0.0 9.9e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAZ51439.1 - 0.00042 20.3 0.0 0.0022 18.0 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EAZ51439.1 - 0.011 14.6 0.0 0.054 12.3 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KRBA1 PF15287.1 EAZ51440.1 - 0.25 10.7 1.9 0.39 10.0 1.3 1.2 1 0 0 1 1 1 0 KRBA1 family repeat UbiA PF01040.13 EAZ51441.1 - 6.5e-06 25.5 1.2 7.6e-06 25.3 0.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Kinesin PF00225.18 EAZ51442.1 - 2.4e-100 335.5 5.5 2.4e-100 335.5 3.8 2.1 2 1 0 2 2 2 1 Kinesin motor domain TRAPP PF04051.11 EAZ51443.1 - 8.7e-35 119.4 0.1 1.1e-34 119.1 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF2399 PF09664.5 EAZ51444.1 - 1.2e-06 28.4 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) DUF2220 PF09983.4 EAZ51444.1 - 0.0004 19.5 0.0 0.00051 19.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) Pkinase PF00069.20 EAZ51445.1 - 1.6e-46 158.5 0.0 5.9e-45 153.4 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51445.1 - 1.2e-44 152.3 0.0 2.2e-43 148.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EAZ51446.1 - 7.9e-73 244.7 0.0 1.1e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51446.1 - 5.7e-33 114.0 0.0 1e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAZ51446.1 - 0.011 14.7 0.2 0.046 12.7 0.1 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EAZ51447.1 - 6.9e-69 231.8 0.0 8.5e-69 231.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51447.1 - 2.6e-34 118.4 0.0 3.3e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51447.1 - 2e-05 23.7 0.0 3.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAZ51447.1 - 0.022 13.8 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EAZ51447.1 - 0.031 13.1 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kinesin PF00225.18 EAZ51448.1 - 5.6e-84 281.6 11.4 5.6e-84 281.6 7.9 2.3 2 1 0 2 2 2 1 Kinesin motor domain IstB_IS21 PF01695.12 EAZ51448.1 - 0.094 12.1 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ZYG-11_interact PF05884.7 EAZ51449.1 - 2.1 7.3 6.5 1.2 8.1 2.9 1.7 1 1 0 1 1 1 0 Interactor of ZYG-11 DeoC PF01791.4 EAZ51450.1 - 2.1e-08 33.7 0.1 9.8e-08 31.5 0.0 2.1 2 1 0 2 2 2 1 DeoC/LacD family aldolase LNS2 PF08235.8 EAZ51451.1 - 2.8e-64 215.4 0.0 4.7e-64 214.7 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EAZ51451.1 - 1.1e-31 108.7 0.0 3.3e-31 107.2 0.0 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region zf-C2HC5 PF06221.8 EAZ51452.1 - 1.1e-06 28.2 7.1 0.012 15.3 1.6 2.4 2 0 0 2 2 2 2 Putative zinc finger motif, C2HC5-type Kelch_4 PF13418.1 EAZ51453.1 - 6.8e-45 150.6 4.3 2e-11 43.4 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EAZ51453.1 - 8.8e-43 143.5 6.0 1.1e-08 35.0 0.0 7.4 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EAZ51453.1 - 2.2e-30 104.0 8.4 5.6e-07 29.3 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EAZ51453.1 - 1.1e-26 91.8 8.6 0.00012 22.1 0.1 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EAZ51453.1 - 2.3e-24 84.1 7.0 1.8e-06 27.4 0.0 6.3 6 0 0 6 6 6 5 Kelch motif BTB PF00651.26 EAZ51453.1 - 4.5e-23 81.3 5.3 1.1e-22 80.0 1.2 2.3 1 1 1 2 2 2 1 BTB/POZ domain Kelch_1 PF01344.20 EAZ51453.1 - 2.4e-20 71.7 9.4 1.1e-06 28.1 0.0 6.4 6 0 0 6 6 6 3 Kelch motif BACK PF07707.10 EAZ51453.1 - 0.027 14.2 2.0 0.35 10.7 0.1 3.0 3 1 0 3 3 3 0 BTB And C-terminal Kelch DUF1265 PF06887.9 EAZ51453.1 - 0.055 13.1 11.8 0.81 9.3 1.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1265) DEAD PF00270.24 EAZ51454.1 - 1.9e-40 138.1 0.3 1e-39 135.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAZ51454.1 - 1.9e-26 91.6 0.6 6.2e-26 90.0 0.1 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EAZ51454.1 - 0.01 14.6 0.0 0.029 13.1 0.0 1.6 1 1 1 2 2 2 0 SNF2 family N-terminal domain ResIII PF04851.10 EAZ51454.1 - 0.023 14.5 0.0 0.023 14.5 0.0 2.5 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit DUF258 PF03193.11 EAZ51454.1 - 0.12 11.5 0.6 1.1 8.4 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF258 E1-E2_ATPase PF00122.15 EAZ51455.1 - 2.6e-33 114.9 4.0 3.9e-33 114.4 0.5 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EAZ51455.1 - 3.2e-07 30.9 0.0 1.3e-06 28.9 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EAZ51455.1 - 1.2e-06 28.5 1.7 3.4e-06 27.0 0.3 2.4 2 0 0 2 2 2 1 Heavy-metal-associated domain HAD PF12710.2 EAZ51455.1 - 0.02 15.0 0.0 0.11 12.6 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase tRNA-synt_1 PF00133.17 EAZ51456.1 - 3.3e-213 709.0 0.5 1e-212 707.3 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EAZ51456.1 - 2.9e-28 98.5 2.7 1.1e-26 93.4 0.4 2.6 2 0 0 2 2 2 2 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EAZ51456.1 - 9.2e-19 67.3 4.2 9.1e-07 27.8 0.1 4.4 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EAZ51456.1 - 4.1e-05 22.8 1.6 0.00013 21.1 0.0 2.6 3 1 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain DUF1342 PF07072.6 EAZ51456.1 - 0.1 12.2 1.1 3.2 7.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1342) DEAD PF00270.24 EAZ51457.1 - 5.8e-46 156.0 0.0 2.2e-45 154.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAZ51457.1 - 9.4e-20 70.2 0.0 2.3e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EAZ51457.1 - 5.5e-19 67.4 0.5 1.1e-18 66.4 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EAZ51457.1 - 0.0025 17.6 0.0 0.01 15.6 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EAZ51457.1 - 0.018 14.6 0.0 0.36 10.3 0.0 2.4 1 1 0 1 1 1 0 AAA domain Cnd2 PF05786.9 EAZ51458.1 - 5.2e-22 78.1 15.8 3.8e-18 65.4 1.7 3.3 3 0 0 3 3 3 2 Condensin complex subunit 2 RRM_1 PF00076.17 EAZ51459.1 - 3.1e-36 122.8 0.0 1.8e-18 65.9 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAZ51459.1 - 5.1e-35 119.2 0.0 2.1e-18 66.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAZ51459.1 - 1.8e-16 59.7 0.1 1e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAZ51459.1 - 0.0046 16.7 1.3 0.71 9.7 0.0 4.0 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EAZ51459.1 - 0.023 14.4 0.0 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 EAZ51460.1 - 1e-33 116.5 0.0 2.2e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51460.1 - 1.4e-30 106.2 0.0 2.4e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3125 PF11323.3 EAZ51460.1 - 0.015 15.0 0.0 0.05 13.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3125) Chlamy_scaf PF09675.5 EAZ51460.1 - 0.024 14.6 0.1 1.6 8.7 0.0 2.7 2 0 0 2 2 2 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) tRNA-synt_1c PF00749.16 EAZ51461.1 - 5.9e-106 353.6 0.0 7.5e-106 353.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EAZ51461.1 - 2e-36 125.3 0.0 6.1e-36 123.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Coatomer_WDAD PF04053.9 EAZ51462.1 - 2.3e-66 224.4 15.0 9.2e-61 205.9 2.7 2.8 3 1 0 3 3 3 2 Coatomer WD associated region COPI_C PF06957.6 EAZ51462.1 - 2.3e-58 197.7 0.0 4.4e-58 196.8 0.0 1.4 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EAZ51462.1 - 2.7e-51 169.6 22.5 2.4e-11 43.0 0.0 8.4 8 0 0 8 8 8 5 WD domain, G-beta repeat TPR_2 PF07719.12 EAZ51462.1 - 0.12 12.3 0.0 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAZ51462.1 - 0.16 12.6 0.0 1.3 9.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Ras PF00071.17 EAZ51463.1 - 6.4e-57 191.4 0.1 7.6e-57 191.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAZ51463.1 - 6.7e-21 75.0 0.0 9.7e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAZ51463.1 - 4.7e-14 51.9 0.0 6e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAZ51463.1 - 6.6e-06 25.6 0.1 0.00023 20.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EAZ51463.1 - 9.3e-05 22.3 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EAZ51463.1 - 0.00083 18.9 0.0 0.4 10.1 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.7 EAZ51463.1 - 0.0021 17.2 0.0 0.0029 16.7 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EAZ51463.1 - 0.0024 17.3 0.1 0.031 13.7 0.1 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 EAZ51463.1 - 0.025 13.3 0.2 1.1 8.0 0.0 2.1 1 1 1 2 2 2 0 ArgK protein AAA_22 PF13401.1 EAZ51463.1 - 0.029 14.4 0.1 0.062 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAZ51463.1 - 0.052 13.5 0.1 0.09 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EAZ51463.1 - 0.071 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 EAZ51463.1 - 0.093 11.9 0.1 0.56 9.4 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.13 EAZ51463.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Septin Pkinase PF00069.20 EAZ51464.1 - 1.8e-32 112.5 0.0 3.5e-32 111.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51464.1 - 2e-08 33.6 0.0 3.8e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51464.1 - 3.7e-08 32.6 0.8 2.1e-06 26.9 0.6 2.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EAZ51464.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EAZ51464.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ANKH PF07260.6 EAZ51464.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Progressive ankylosis protein (ANKH) DEAD PF00270.24 EAZ51465.1 - 5.7e-41 139.8 0.0 8e-41 139.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAZ51465.1 - 1e-23 83.0 0.1 1.7e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S4 PF01479.20 EAZ51466.1 - 6.5e-12 44.6 0.7 1.3e-11 43.6 0.5 1.5 1 0 0 1 1 1 1 S4 domain Aha1_N PF09229.6 EAZ51467.1 - 2.2e-22 79.3 0.3 1.4e-21 76.7 0.2 2.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal TPR_11 PF13414.1 EAZ51467.1 - 2.4e-14 52.7 4.8 2.5e-08 33.4 0.0 3.0 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EAZ51467.1 - 4.5e-12 44.9 1.8 0.0014 18.3 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EAZ51467.1 - 8.5e-12 44.1 4.7 5.1e-06 25.8 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 EAZ51467.1 - 1.7e-07 31.2 3.0 0.067 13.6 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAZ51467.1 - 6.4e-07 29.8 0.0 0.0019 18.8 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAZ51467.1 - 4.5e-06 26.0 0.5 0.0092 15.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAZ51467.1 - 2.7e-05 23.9 1.1 0.063 13.1 0.1 3.6 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 EAZ51467.1 - 0.00012 21.9 1.7 2.3 8.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAZ51467.1 - 0.00019 20.9 0.8 0.12 12.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EAZ51467.1 - 0.00021 21.0 0.0 0.00085 19.1 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAZ51467.1 - 0.00048 20.0 0.8 0.23 11.4 0.1 3.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAZ51467.1 - 0.00091 19.6 0.0 0.2 12.4 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAZ51467.1 - 0.031 14.6 3.1 0.44 10.9 0.6 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EAZ51467.1 - 0.055 13.3 0.5 0.055 13.3 0.4 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Pro_isomerase PF00160.16 EAZ51468.1 - 3.3e-35 121.6 0.0 4.5e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EAZ51468.1 - 6.2e-16 57.7 0.2 1.6e-15 56.4 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAZ51468.1 - 1.6e-11 44.0 0.0 3.2e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAZ51468.1 - 4.2e-08 32.9 0.1 1.1e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CKS PF01111.14 EAZ51470.1 - 5e-20 71.1 0.1 5.6e-20 70.9 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Ribosomal_L14 PF00238.14 EAZ51471.1 - 0.09 12.5 0.2 1.5 8.6 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L14p/L23e Pkinase PF00069.20 EAZ51473.1 - 1.1e-59 201.7 0.1 2.3e-59 200.6 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51473.1 - 9.6e-22 77.2 0.7 4.3e-20 71.8 0.3 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EAZ51473.1 - 0.023 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EAZ51473.1 - 0.029 13.4 0.0 0.066 12.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PTH2 PF01981.11 EAZ51474.1 - 6e-36 122.6 0.1 6.7e-36 122.5 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 AsnC_trans_reg PF01037.16 EAZ51474.1 - 0.0014 18.2 0.0 0.0044 16.6 0.0 1.7 2 0 0 2 2 2 1 AsnC family PYRIN PF02758.11 EAZ51474.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain PIP5K PF01504.13 EAZ51475.1 - 1.5e-78 263.3 7.7 4.5e-78 261.8 5.3 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_1 PF00036.27 EAZ51475.1 - 0.00082 18.5 0.3 0.0032 16.6 0.2 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EAZ51475.1 - 0.0049 16.6 0.1 0.022 14.5 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.1 EAZ51475.1 - 0.0059 16.1 0.9 0.059 12.9 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EAZ51475.1 - 0.029 14.5 1.3 0.19 11.8 0.9 2.3 1 1 0 1 1 1 0 EF-hand domain pair PTH2 PF01981.11 EAZ51476.1 - 3.1e-11 42.9 0.1 3.9e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Sigma70_r1_2 PF00140.15 EAZ51476.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 PrmA PF06325.8 EAZ51477.1 - 9e-11 41.4 0.1 1.4e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EAZ51477.1 - 2.6e-09 36.8 2.4 1.7e-08 34.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 EAZ51477.1 - 3e-07 29.7 0.5 3.7e-07 29.4 0.4 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 EAZ51477.1 - 6.3e-07 29.2 0.0 1.4e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAZ51477.1 - 7.9e-07 29.6 0.0 1.7e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAZ51477.1 - 8.9e-07 29.3 0.0 2.5e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAZ51477.1 - 1.7e-06 27.5 0.1 3e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EAZ51477.1 - 5.5e-06 26.4 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAZ51477.1 - 1.5e-05 25.3 0.0 0.0007 19.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAZ51477.1 - 0.00054 20.4 0.2 0.0015 19.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EAZ51477.1 - 0.0019 18.2 0.0 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 EAZ51477.1 - 0.0035 16.1 0.0 0.0076 14.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EAZ51477.1 - 0.0036 16.4 0.1 0.0056 15.8 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 EAZ51477.1 - 0.024 13.8 0.1 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 EAZ51477.1 - 0.04 13.3 1.0 0.067 12.6 0.1 1.7 2 0 0 2 2 2 0 Putative methyltransferase UFC1 PF08694.6 EAZ51478.1 - 4.8e-65 217.9 0.3 5.1e-65 217.8 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.21 EAZ51478.1 - 0.042 13.2 0.3 0.073 12.4 0.2 1.5 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme WD40 PF00400.27 EAZ51479.1 - 2.1e-12 46.3 8.4 0.53 10.2 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EAZ51479.1 - 1.8e-08 34.3 0.5 0.044 13.4 0.0 3.4 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EAZ51479.1 - 0.00088 18.1 1.0 1.8 7.2 0.0 3.1 1 1 2 3 3 3 2 Coatomer WD associated region PD40 PF07676.7 EAZ51479.1 - 0.0075 15.9 1.0 4.4 7.0 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Tachylectin PF14517.1 EAZ51479.1 - 0.011 15.1 0.0 0.079 12.2 0.0 2.3 2 1 0 2 2 2 0 Tachylectin IKI3 PF04762.7 EAZ51479.1 - 0.026 12.3 0.1 0.23 9.2 0.1 2.0 1 1 0 1 1 1 0 IKI3 family Proteasome_A_N PF10584.4 EAZ51479.1 - 0.071 12.4 0.0 0.071 12.4 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 EAZ51480.1 - 8.5e-32 107.8 26.2 5.9e-10 38.6 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat IKI3 PF04762.7 EAZ51480.1 - 8.7e-05 20.5 1.5 0.00012 20.0 1.0 1.2 1 0 0 1 1 1 1 IKI3 family BBS2_Mid PF14783.1 EAZ51480.1 - 0.0072 16.0 0.0 3.5 7.4 0.0 3.4 2 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region adh_short PF00106.20 EAZ51481.1 - 8.1e-14 51.8 0.0 1.1e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAZ51481.1 - 5.7e-06 26.2 0.0 7.7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAZ51481.1 - 4.8e-05 23.1 0.0 6.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAZ51481.1 - 0.011 15.2 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TIR-like PF10137.4 EAZ51481.1 - 0.04 13.5 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain DUF2626 PF11117.3 EAZ51481.1 - 3.5 8.1 9.7 7.8 6.9 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2626) Cnd1_N PF12922.2 EAZ51482.1 - 0.052 13.1 1.5 0.076 12.6 1.0 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Rcd1 PF04078.8 EAZ51483.1 - 2.4e-120 400.2 0.4 2.9e-120 400.0 0.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like FlgH PF02107.11 EAZ51483.1 - 0.013 15.0 1.0 0.021 14.3 0.7 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein DUF605 PF04652.11 EAZ51483.1 - 0.62 9.4 5.8 0.92 8.8 4.0 1.2 1 0 0 1 1 1 0 Vta1 like Sec23_trunk PF04811.10 EAZ51484.1 - 4.5e-58 196.4 0.0 7e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EAZ51484.1 - 4.8e-17 62.2 0.0 1.7e-16 60.5 0.0 2.0 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EAZ51484.1 - 3.9e-15 55.1 3.6 8.1e-15 54.1 2.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 EAZ51484.1 - 3.3e-10 39.3 0.2 1.4e-09 37.2 0.1 2.0 1 1 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 EAZ51484.1 - 1.1e-06 28.2 0.0 5.6e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat zf-RanBP PF00641.13 EAZ51484.1 - 0.11 11.5 0.2 0.32 10.1 0.1 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others WD40 PF00400.27 EAZ51485.1 - 9.8e-22 75.9 3.1 7.1e-06 25.7 0.0 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat RIO1 PF01163.17 EAZ51486.1 - 2e-11 43.5 0.2 2.9e-11 43.0 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EAZ51486.1 - 3.4e-10 39.4 0.3 4.4e-10 39.0 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EAZ51486.1 - 5.7e-09 35.5 4.0 7.4e-09 35.1 2.8 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EAZ51486.1 - 1.5e-08 33.9 0.0 2.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAZ51486.1 - 0.00014 21.6 0.0 0.0054 16.4 0.5 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EAZ51486.1 - 0.0003 20.0 0.3 0.00048 19.3 0.2 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EAZ51486.1 - 0.064 12.8 3.2 0.12 11.8 2.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Fcf1 PF04900.7 EAZ51487.1 - 3.6e-21 75.1 0.4 7.5e-14 51.6 0.0 2.4 1 1 1 2 2 2 2 Fcf1 RPAP2_Rtr1 PF04181.8 EAZ51487.1 - 0.026 14.6 1.1 0.044 13.8 0.8 1.6 1 1 0 1 1 1 0 Rtr1/RPAP2 family DUF2321 PF10083.4 EAZ51487.1 - 0.032 13.7 0.2 0.63 9.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Clat_adaptor_s PF01217.15 EAZ51488.1 - 1.4e-42 144.7 6.3 1.6e-42 144.5 4.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-DHHC PF01529.15 EAZ51489.1 - 2.6e-37 127.9 4.3 3.5e-37 127.4 3.0 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Cation_efflux PF01545.16 EAZ51489.1 - 0.0069 15.4 1.0 0.0086 15.1 0.7 1.1 1 0 0 1 1 1 1 Cation efflux family CbiX PF01903.12 EAZ51489.1 - 0.15 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 CbiX Sedlin_N PF04628.8 EAZ51490.1 - 2.6e-36 124.4 0.0 2.9e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EAZ51490.1 - 1.1e-05 25.2 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Pkinase PF00069.20 EAZ51491.1 - 1.8e-55 187.9 0.0 2.3e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51491.1 - 4.1e-40 137.4 0.0 8.7e-40 136.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51491.1 - 5.9e-08 32.0 0.0 1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAZ51491.1 - 0.16 10.9 0.1 0.37 9.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EAZ51492.1 - 4.3e-58 196.5 1.6 4.3e-58 196.5 1.1 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51492.1 - 1e-30 106.7 0.3 2.5e-29 102.1 0.1 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EAZ51492.1 - 1.7e-05 24.2 0.1 3.7e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EAZ51492.1 - 0.0039 16.2 0.5 0.0068 15.4 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAZ51492.1 - 0.028 13.3 0.0 0.059 12.3 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Acatn PF13000.2 EAZ51493.1 - 4.4e-51 174.0 14.4 8.5e-51 173.0 10.0 1.4 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 ATP-synt_ab PF00006.20 EAZ51495.1 - 1.2e-66 224.3 0.0 1.7e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 EAZ51495.1 - 4.3e-14 52.4 0.9 9.3e-14 51.4 0.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 EAZ51495.1 - 0.00021 21.7 0.7 0.00061 20.2 0.5 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Miro PF08477.8 EAZ51495.1 - 0.028 14.9 0.0 0.078 13.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein HAS-barrel PF09378.5 EAZ51495.1 - 0.087 12.7 3.4 0.55 10.1 1.1 3.3 2 1 1 3 3 3 0 HAS barrel domain Pkinase PF00069.20 EAZ51496.1 - 1.9e-59 200.9 0.0 2.2e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51496.1 - 4.2e-20 71.9 0.0 5.5e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAZ51496.1 - 2.4e-07 30.7 0.0 8.6e-06 25.6 0.0 2.6 1 1 2 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAZ51496.1 - 0.029 13.9 3.2 0.035 13.6 0.0 2.4 3 0 0 3 3 3 0 Choline/ethanolamine kinase Kdo PF06293.9 EAZ51496.1 - 0.065 12.2 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EAZ51497.1 - 3.3e-76 255.8 0.0 9.5e-76 254.3 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51497.1 - 7.7e-42 143.1 0.0 1.4e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51497.1 - 1.5e-06 27.3 0.0 4.3e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EAZ51497.1 - 5.8e-05 22.5 0.1 0.00015 21.1 0.1 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EAZ51497.1 - 0.025 14.3 0.1 0.045 13.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribonuc_red_sm PF00268.16 EAZ51498.1 - 7.6e-27 94.0 10.7 1.1e-14 54.1 1.6 2.0 1 1 1 2 2 2 2 Ribonucleotide reductase, small chain E1-E2_ATPase PF00122.15 EAZ51499.1 - 2e-16 59.7 6.1 7.5e-13 48.0 2.5 3.7 3 1 0 3 3 3 2 E1-E2 ATPase HAD PF12710.2 EAZ51499.1 - 2.6e-15 57.1 0.0 1.3e-14 54.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAZ51499.1 - 3.7e-14 53.6 0.0 1.4e-12 48.4 0.0 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase LRR_4 PF12799.2 EAZ51500.1 - 3.9e-37 125.2 61.1 1.9e-08 33.7 5.4 6.4 4 2 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAZ51500.1 - 1.2e-21 76.2 49.8 1.4e-07 31.1 1.4 5.9 1 1 5 7 7 7 7 Leucine rich repeat LRR_9 PF14580.1 EAZ51500.1 - 1.1e-16 60.9 24.2 1.4e-05 24.7 0.3 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.28 EAZ51500.1 - 4.2e-12 44.3 43.7 0.071 13.1 0.4 11.3 10 2 2 12 12 12 6 Leucine Rich Repeat LRR_7 PF13504.1 EAZ51500.1 - 6.6e-09 34.5 28.0 0.78 10.1 0.0 10.3 9 1 0 9 9 9 3 Leucine rich repeat LRR_6 PF13516.1 EAZ51500.1 - 4.8e-08 32.2 38.7 0.19 11.9 0.1 10.5 8 2 3 11 11 11 4 Leucine Rich repeat Latarcin PF10279.4 EAZ51500.1 - 0.0086 16.2 0.0 0.92 9.7 0.0 3.0 1 1 0 1 1 1 1 Latarcin precursor AAA PF00004.24 EAZ51501.1 - 3.4e-43 146.9 0.0 6.7e-43 146.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EAZ51501.1 - 1.8e-07 31.2 0.0 4.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EAZ51501.1 - 1.6e-06 27.8 0.0 5.5e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAZ51501.1 - 4.3e-06 26.8 0.3 0.00018 21.6 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAZ51501.1 - 7.3e-06 26.0 0.1 3.1e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EAZ51501.1 - 2.3e-05 25.1 0.3 0.00024 21.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EAZ51501.1 - 0.00013 21.1 0.0 0.00027 20.0 0.0 1.5 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAZ51501.1 - 0.00015 21.4 0.1 0.00032 20.4 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EAZ51501.1 - 0.0004 19.8 0.0 0.00091 18.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EAZ51501.1 - 0.00068 18.4 0.1 0.002 16.9 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 EAZ51501.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EAZ51501.1 - 0.0016 18.3 0.0 0.0043 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EAZ51501.1 - 0.0019 18.4 1.0 0.01 16.1 0.0 2.6 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EAZ51501.1 - 0.0025 17.2 0.1 0.077 12.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 EAZ51501.1 - 0.0025 17.4 0.0 0.58 9.8 0.0 2.4 1 1 0 2 2 2 1 NACHT domain KaiC PF06745.8 EAZ51501.1 - 0.0028 16.8 0.9 0.019 14.0 0.0 2.5 3 0 0 3 3 3 1 KaiC AAA_28 PF13521.1 EAZ51501.1 - 0.004 17.1 0.1 0.0096 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EAZ51501.1 - 0.0045 16.1 0.0 0.0087 15.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EAZ51501.1 - 0.0061 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EAZ51501.1 - 0.0064 15.6 0.1 0.015 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EAZ51501.1 - 0.0098 15.1 0.1 0.078 12.2 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein RNA_helicase PF00910.17 EAZ51501.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EAZ51501.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain HR1 PF02185.11 EAZ51501.1 - 0.02 14.6 2.0 0.02 14.6 1.4 2.0 2 0 0 2 2 1 0 Hr1 repeat DUF4200 PF13863.1 EAZ51501.1 - 0.02 14.8 0.7 0.05 13.5 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Sigma54_activat PF00158.21 EAZ51501.1 - 0.025 14.0 1.2 0.11 11.9 0.0 2.6 3 1 0 3 3 3 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EAZ51501.1 - 0.039 12.8 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EAZ51501.1 - 0.046 13.7 0.1 0.18 11.8 0.0 2.2 2 1 0 2 2 1 0 Sigma-54 interaction domain DUF815 PF05673.8 EAZ51501.1 - 0.05 12.5 0.0 0.12 11.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF815) Tho2 PF11262.3 EAZ51501.1 - 0.08 11.9 0.4 0.12 11.3 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Pkinase PF00069.20 EAZ51502.1 - 2.3e-31 108.9 0.0 2.5e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51502.1 - 4.4e-15 55.4 0.0 4.8e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51502.1 - 1.8e-05 23.8 0.0 2.1e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAZ51502.1 - 0.0011 18.1 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EFG_II PF14492.1 EAZ51502.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Elongation Factor G, domain II DnaJ PF00226.26 EAZ51503.1 - 3.7e-22 77.8 1.5 3.7e-22 77.8 1.1 2.5 2 0 0 2 2 2 1 DnaJ domain YfbU PF03887.9 EAZ51503.1 - 0.55 9.7 5.5 0.68 9.4 2.0 2.1 1 1 1 2 2 2 0 YfbU domain Scm3 PF10384.4 EAZ51503.1 - 6.6 6.2 9.7 1.4 8.4 0.1 3.2 3 0 0 3 3 3 0 Centromere protein Scm3 Ribosom_S12_S23 PF00164.20 EAZ51504.1 - 8.2e-40 135.0 0.7 9.7e-40 134.7 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_15 PF09445.5 EAZ51504.1 - 0.0058 16.2 0.0 0.0068 15.9 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase OB_NTP_bind PF07717.11 EAZ51505.1 - 1.1e-30 105.8 0.0 2.9e-30 104.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EAZ51505.1 - 6e-30 103.2 0.0 4.5e-29 100.4 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EAZ51505.1 - 4.2e-09 36.1 0.0 1.3e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAZ51505.1 - 7.6e-07 28.7 0.1 1.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAZ51505.1 - 1.4e-06 28.4 0.0 4.4e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EAZ51505.1 - 0.001 18.0 0.0 0.0023 16.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EAZ51505.1 - 0.0082 15.8 0.1 0.021 14.5 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 EAZ51505.1 - 0.011 15.8 0.9 1.1 9.4 0.0 3.8 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EAZ51505.1 - 0.014 14.5 0.3 0.032 13.3 0.0 1.7 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 EAZ51505.1 - 0.02 14.1 0.0 0.071 12.3 0.0 1.9 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 EAZ51505.1 - 0.02 14.7 0.3 0.93 9.3 0.2 3.1 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 EAZ51505.1 - 0.043 14.3 0.1 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 EAZ51505.1 - 0.065 13.5 4.1 0.59 10.4 0.1 3.5 3 1 0 4 4 4 0 ABC transporter AAA_30 PF13604.1 EAZ51505.1 - 0.21 11.1 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EAZ51505.1 - 0.44 10.8 0.0 0.44 10.8 0.0 3.8 3 2 0 3 3 2 0 AAA domain Pkinase PF00069.20 EAZ51506.1 - 2.5e-65 220.2 0.0 5.4e-65 219.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51506.1 - 2.1e-28 99.1 0.0 7.2e-28 97.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Trypan_PARP PF05887.6 EAZ51506.1 - 0.99 9.2 9.3 1.7 8.4 6.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Atrophin-1 PF03154.10 EAZ51506.1 - 3.2 5.7 39.6 0.57 8.2 8.0 2.3 1 1 1 2 2 2 0 Atrophin-1 family MIP-T3 PF10243.4 EAZ51506.1 - 3.2 6.0 39.0 5 5.4 27.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF106 PF01956.11 EAZ51507.1 - 1.2e-17 63.9 2.6 1.5e-17 63.6 1.8 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF106 Lipl32 PF12103.3 EAZ51507.1 - 0.072 12.5 0.3 0.11 11.9 0.1 1.4 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order DUF4229 PF14012.1 EAZ51507.1 - 0.11 12.4 2.4 0.19 11.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Myosin_tail_1 PF01576.14 EAZ51507.1 - 0.3 8.7 2.4 0.39 8.3 1.7 1.0 1 0 0 1 1 1 0 Myosin tail SRPRB PF09439.5 EAZ51508.1 - 6.4e-20 71.1 1.0 1.6e-19 69.8 0.7 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EAZ51508.1 - 2.4e-12 46.4 0.2 6.7e-12 44.9 0.1 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EAZ51508.1 - 6.6e-09 35.7 1.2 1.1e-08 34.9 0.8 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EAZ51508.1 - 2.9e-06 26.6 0.4 4.5e-06 25.9 0.3 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EAZ51508.1 - 3.3e-06 27.5 0.1 7.9e-06 26.3 0.1 1.7 1 1 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EAZ51508.1 - 0.0005 20.2 0.0 0.0013 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EAZ51508.1 - 0.0022 17.4 0.7 0.0055 16.1 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 EAZ51508.1 - 0.0029 17.1 0.1 0.0046 16.4 0.1 1.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EAZ51508.1 - 0.0037 16.1 1.2 0.034 12.9 0.8 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 EAZ51508.1 - 0.0055 17.5 0.3 0.0095 16.7 0.2 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EAZ51508.1 - 0.0057 15.8 0.3 0.03 13.5 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 DUF3987 PF13148.1 EAZ51508.1 - 0.0059 15.2 0.0 0.011 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) AAA_33 PF13671.1 EAZ51508.1 - 0.0091 15.8 0.1 0.014 15.2 0.1 1.3 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EAZ51508.1 - 0.0093 15.6 1.0 0.015 14.9 0.7 1.5 1 1 0 1 1 1 1 Archaeal ATPase cobW PF02492.14 EAZ51508.1 - 0.014 14.8 2.2 0.15 11.4 0.1 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EAZ51508.1 - 0.016 14.9 0.0 0.025 14.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EAZ51508.1 - 0.018 14.6 1.1 0.044 13.3 0.3 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EAZ51508.1 - 0.02 14.8 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EAZ51508.1 - 0.026 14.1 0.2 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Ras PF00071.17 EAZ51508.1 - 0.029 13.7 2.7 0.35 10.2 1.9 2.4 1 1 0 1 1 1 0 Ras family MobB PF03205.9 EAZ51508.1 - 0.036 13.7 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EAZ51508.1 - 0.046 13.6 1.6 0.11 12.3 1.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EAZ51508.1 - 0.049 13.1 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EAZ51508.1 - 0.062 13.6 9.1 5 7.4 6.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAZ51508.1 - 0.064 13.5 0.2 0.11 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EAZ51508.1 - 0.067 13.3 0.3 0.13 12.4 0.2 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 EAZ51508.1 - 0.076 12.5 1.2 0.61 9.5 0.3 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein T2SE PF00437.15 EAZ51508.1 - 0.098 11.5 0.8 0.16 10.8 0.6 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EAZ51508.1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EAZ51508.1 - 0.11 12.3 1.6 0.18 11.6 0.1 2.0 1 1 1 2 2 2 0 Dynamin family Septin PF00735.13 EAZ51508.1 - 0.11 11.4 4.5 1.2 8.1 0.1 2.5 1 1 2 3 3 3 0 Septin RNA_helicase PF00910.17 EAZ51508.1 - 0.15 12.2 1.9 0.55 10.4 0.8 2.3 1 1 1 2 2 2 0 RNA helicase AAA_28 PF13521.1 EAZ51508.1 - 0.17 11.8 0.2 0.26 11.2 0.2 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAZ51508.1 - 0.23 11.7 4.3 0.38 11.0 3.0 1.5 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 EAZ51508.1 - 0.25 11.0 1.7 0.93 9.1 0.3 2.1 1 1 1 2 2 2 0 NTPase SMC_N PF02463.14 EAZ51508.1 - 0.32 10.2 1.8 1.3 8.2 0.1 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAZ51508.1 - 0.88 9.4 16.1 0.26 11.2 9.1 1.7 2 1 0 2 2 1 0 AAA domain Ribosomal_L28e PF01778.12 EAZ51509.1 - 1.7e-26 92.9 0.4 1.7e-26 92.9 0.3 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EAZ51509.1 - 4.8e-18 65.0 10.9 8.8e-18 64.2 7.6 1.4 1 0 0 1 1 1 1 Mak16 protein C-terminal region APC10 PF03256.11 EAZ51510.1 - 9.6e-44 149.2 0.0 1.1e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EAZ51510.1 - 0.00013 21.8 0.1 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain DUF1764 PF08576.5 EAZ51511.1 - 3.3e-05 24.5 2.0 4.6e-05 24.1 1.4 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) DUF1154 PF06631.6 EAZ51511.1 - 2.8 7.6 8.3 1 9.0 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) Kinesin PF00225.18 EAZ51512.1 - 1.8e-65 220.8 0.7 1.8e-65 220.8 0.5 2.6 3 1 0 3 3 3 1 Kinesin motor domain Kinesin PF00225.18 EAZ51513.1 - 1.3e-95 319.9 6.7 1.3e-95 319.9 4.7 2.7 3 1 1 4 4 4 1 Kinesin motor domain BT1 PF03092.11 EAZ51514.1 - 1.5e-07 30.5 0.1 2.6e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 BT1 family PUCC PF03209.10 EAZ51514.1 - 0.038 12.7 0.7 2.5 6.6 0.1 2.2 2 0 0 2 2 2 0 PUCC protein Ion_trans_2 PF07885.11 EAZ51515.1 - 6.6e-13 48.1 0.1 3.3e-12 45.9 0.1 2.2 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.13 EAZ51515.1 - 6.4e-06 26.0 0.8 2.6e-05 24.1 0.1 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit RRM_5 PF13893.1 EAZ51516.1 - 1.1e-12 47.5 0.5 2.9e-11 43.0 0.3 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAZ51516.1 - 9.9e-11 41.1 0.6 1.9e-07 30.6 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAZ51516.1 - 9.4e-08 31.9 0.1 2.9e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 EAZ51516.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) CDT1 PF08839.6 EAZ51516.1 - 0.028 14.3 0.2 0.066 13.1 0.1 1.6 1 1 0 1 1 1 0 DNA replication factor CDT1 like Myb_DNA-binding PF00249.26 EAZ51517.1 - 3e-21 75.1 3.8 1.1e-09 38.2 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAZ51517.1 - 4.2e-18 65.2 3.4 3.8e-13 49.3 0.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EAZ51517.1 - 0.008 16.2 0.6 0.17 12.0 0.1 2.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Topoisom_bac PF01131.15 EAZ51518.1 - 2e-101 339.7 0.0 2.4e-101 339.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EAZ51518.1 - 1.2e-17 63.6 0.0 2.4e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Toprim domain PolC_DP2 PF03833.8 EAZ51518.1 - 1.1 6.8 3.2 1.6 6.2 2.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHF5 PF03660.9 EAZ51519.1 - 2.5e-41 140.0 14.3 2.7e-41 139.9 9.9 1.0 1 0 0 1 1 1 1 PHF5-like protein UPF0547 PF10571.4 EAZ51519.1 - 0.0049 16.5 3.1 0.0049 16.5 2.1 3.1 3 0 0 3 3 3 1 Uncharacterised protein family UPF0547 PolC_DP2 PF03833.8 EAZ51519.1 - 0.054 11.1 5.5 0.059 11.0 3.8 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.2 EAZ51519.1 - 0.73 9.7 15.6 0.72 9.7 8.5 2.5 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 EAZ51519.1 - 0.92 9.2 15.3 2.6 7.8 3.5 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF2039 PF10217.4 EAZ51519.1 - 7.1 6.7 16.2 1.4e+02 2.5 11.2 2.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Fer4_8 PF13183.1 EAZ51519.1 - 9.4 6.3 19.3 0.26 11.3 0.4 3.0 2 1 0 2 2 2 0 4Fe-4S dicluster domain HECT PF00632.20 EAZ51520.1 - 8.6e-88 294.5 0.7 1.4e-87 293.7 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IPPT PF01715.12 EAZ51521.1 - 1.1e-50 171.9 0.2 1.5e-50 171.6 0.2 1.1 1 0 0 1 1 1 1 IPP transferase DnaJ PF00226.26 EAZ51522.1 - 1.6e-30 104.6 3.6 2.4e-30 104.0 2.5 1.3 1 0 0 1 1 1 1 DnaJ domain OTU PF02338.14 EAZ51523.1 - 6.7e-19 68.6 0.1 2.2e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EAZ51523.1 - 2.7e-08 33.4 1.3 0.0002 20.8 0.1 2.5 1 1 0 2 2 2 2 Peptidase C65 Otubain RCC1 PF00415.13 EAZ51524.1 - 2.2e-73 242.2 24.2 6.8e-14 51.8 0.4 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EAZ51524.1 - 3.3e-36 122.1 43.7 1.6e-07 30.7 0.4 8.2 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.6 EAZ51524.1 - 0.14 11.3 1.3 54 2.8 0.0 3.8 4 0 0 4 4 4 0 TUP1-like enhancer of split Kinesin PF00225.18 EAZ51525.1 - 7e-108 360.2 1.8 7e-108 360.2 1.3 2.8 3 0 0 3 3 3 1 Kinesin motor domain OGG_N PF07934.7 EAZ51525.1 - 1.5 8.8 14.7 21 5.0 0.0 3.9 2 1 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain Reo_sigmaC PF04582.7 EAZ51525.1 - 2.9 6.9 20.0 4.2 6.4 5.3 3.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Gtr1_RagA PF04670.7 EAZ51526.1 - 8.8e-83 276.9 0.6 1.2e-82 276.5 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EAZ51526.1 - 6.2e-06 25.6 0.6 2.4e-05 23.7 0.0 2.1 2 1 0 2 2 2 1 Ras family Arf PF00025.16 EAZ51526.1 - 1.6e-05 24.1 0.0 2.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EAZ51526.1 - 4.6e-05 23.9 0.1 0.00015 22.2 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EAZ51526.1 - 0.00045 20.1 0.1 0.0029 17.5 0.0 2.2 2 1 1 3 3 3 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EAZ51526.1 - 0.014 15.6 0.0 0.035 14.4 0.0 1.9 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EAZ51526.1 - 0.049 13.1 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EAZ51526.1 - 0.1 12.7 0.0 7.5 6.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Fer2 PF00111.22 EAZ51527.1 - 1.8e-12 46.8 0.7 2.2e-12 46.5 0.5 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RRM_1 PF00076.17 EAZ51528.1 - 1.9e-75 248.4 0.1 3.3e-19 68.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAZ51528.1 - 6.2e-57 189.4 0.2 8.2e-17 60.9 0.0 5.3 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAZ51528.1 - 4.9e-36 122.3 0.0 4.8e-08 32.7 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EAZ51528.1 - 1.2e-29 101.7 0.7 2.6e-29 100.6 0.5 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EAZ51528.1 - 0.028 14.1 0.0 18 5.2 0.0 3.6 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Hamartin PF04388.7 EAZ51528.1 - 0.085 11.5 3.7 5 5.6 1.5 2.2 2 0 0 2 2 2 0 Hamartin protein XRCC4 PF06632.7 EAZ51528.1 - 0.21 10.3 6.6 0.34 9.7 4.6 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Ribosomal_L4 PF00573.17 EAZ51529.1 - 5.2e-42 143.4 0.1 5.2e-42 143.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EAZ51529.1 - 2.8e-15 55.9 2.6 2.8e-15 55.9 0.3 2.2 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Pkinase PF00069.20 EAZ51530.1 - 3.3e-65 219.8 0.0 8.2e-65 218.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51530.1 - 1.3e-33 116.1 0.0 2.2e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51530.1 - 3.9e-08 32.5 0.0 6.9e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAZ51530.1 - 0.004 16.2 0.0 0.0092 15.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EAZ51530.1 - 0.033 13.5 0.1 0.076 12.3 0.1 1.5 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 EAZ51530.1 - 0.063 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Collagen PF01391.13 EAZ51531.1 - 2.6 7.6 9.0 38 3.9 6.2 2.4 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Peptidase_M22 PF00814.20 EAZ51532.1 - 6.8e-79 265.1 0.0 8.5e-79 264.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family WD40 PF00400.27 EAZ51533.1 - 1.6e-42 141.8 21.4 1.3e-11 43.9 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EAZ51533.1 - 0.037 13.7 0.1 46 3.6 0.0 3.4 2 2 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EAZ51533.1 - 0.048 11.8 0.0 0.2 9.7 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 TRAPP PF04051.11 EAZ51534.1 - 5e-37 126.7 0.0 5.6e-37 126.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component APC_crr PF05923.7 EAZ51534.1 - 0.12 11.9 0.9 0.24 11.0 0.6 1.4 1 0 0 1 1 1 0 APC cysteine-rich region Ras PF00071.17 EAZ51535.1 - 3.5e-60 202.0 1.7 4.2e-60 201.8 1.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAZ51535.1 - 5.1e-18 65.6 0.4 9.1e-18 64.8 0.1 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EAZ51535.1 - 1.6e-13 50.2 0.4 2e-13 49.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAZ51535.1 - 7.4e-06 25.2 0.4 9.1e-06 24.9 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAZ51535.1 - 2e-05 24.5 0.1 4.6e-05 23.3 0.1 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAZ51535.1 - 3.4e-05 23.3 0.4 8.7e-05 22.0 0.3 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EAZ51535.1 - 0.0022 18.1 0.0 0.0074 16.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EAZ51535.1 - 0.0054 16.3 0.4 0.012 15.1 0.1 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EAZ51535.1 - 0.0057 15.8 0.1 0.016 14.4 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function, DUF258 DUF1327 PF07041.6 EAZ51535.1 - 0.011 15.5 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) ABC_tran PF00005.22 EAZ51535.1 - 0.014 15.6 0.0 0.021 15.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EAZ51535.1 - 0.082 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 EAZ51535.1 - 7.5 5.1 8.9 24 3.4 3.5 2.8 1 1 1 2 2 2 0 G-protein alpha subunit SNF2_N PF00176.18 EAZ51536.1 - 3.1e-74 249.4 1.2 6.9e-74 248.3 0.0 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain SLIDE PF09111.5 EAZ51536.1 - 3.2e-35 120.4 4.5 1.2e-34 118.5 3.1 2.1 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.26 EAZ51536.1 - 2.9e-16 59.1 0.0 8.3e-16 57.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAZ51536.1 - 2.1e-11 43.9 4.2 3.4e-11 43.3 0.0 3.4 5 1 0 5 5 5 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EAZ51536.1 - 3.4e-05 23.4 0.0 7.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 EAZ51536.1 - 0.00054 19.4 0.0 0.00054 19.4 0.0 1.9 2 0 0 2 2 2 1 DEAD_2 DUF2281 PF10047.4 EAZ51536.1 - 0.011 16.0 0.2 0.035 14.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) GTP_EFTU PF00009.22 EAZ51537.1 - 8.7e-51 172.0 0.3 1.9e-50 170.9 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EAZ51537.1 - 6.2e-17 61.2 0.0 2.1e-16 59.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EAZ51537.1 - 3.7e-07 29.9 0.0 1.2e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EAZ51537.1 - 5.5e-06 26.3 2.6 9.1e-06 25.6 0.1 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase EFG_IV PF03764.13 EAZ51537.1 - 0.00021 20.8 0.0 0.00063 19.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 EAZ51537.1 - 0.048 13.7 0.1 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 2 GTP_EFTU PF00009.22 EAZ51538.1 - 6.8e-55 185.4 0.0 1.1e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EAZ51538.1 - 8e-35 118.9 0.2 4.4e-34 116.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EAZ51538.1 - 3.8e-18 65.3 0.7 1.3e-17 63.6 0.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EAZ51538.1 - 1.9e-06 27.4 0.2 5.4e-06 25.9 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EAZ51538.1 - 0.00011 22.1 0.0 0.00046 20.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FlpD PF02662.11 EAZ51538.1 - 0.023 14.3 0.1 0.094 12.4 0.0 1.9 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit Miro PF08477.8 EAZ51538.1 - 0.1 13.1 0.6 1.4 9.4 0.2 2.7 2 1 0 2 2 2 0 Miro-like protein PDEase_I PF00233.14 EAZ51539.1 - 3.5e-31 108.7 15.8 5.3e-29 101.6 8.8 2.9 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase DUF420 PF04238.7 EAZ51539.1 - 0.16 11.9 3.7 0.84 9.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF420) FH2 PF02181.18 EAZ51540.1 - 2.6e-77 260.2 0.3 4.2e-77 259.5 0.2 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain TPR_12 PF13424.1 EAZ51540.1 - 3.1e-16 59.0 0.5 5.7e-09 35.7 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EAZ51540.1 - 2.5e-12 46.3 0.1 0.00018 21.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAZ51540.1 - 1.6e-07 30.8 0.2 4.8e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 TPR repeat DUF4167 PF13763.1 EAZ51540.1 - 0.002 18.1 0.1 0.0082 16.1 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4167) TPR_1 PF00515.23 EAZ51540.1 - 0.0076 15.8 8.5 3.6 7.3 0.5 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAZ51540.1 - 0.024 14.5 7.1 3.1 7.9 0.4 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Kinesin PF00225.18 EAZ51541.1 - 1.7e-110 368.8 2.5 1.7e-110 368.8 1.7 2.6 3 1 0 3 3 3 1 Kinesin motor domain UDPGT PF00201.13 EAZ51541.1 - 0.7 8.3 7.8 0.024 13.2 0.3 2.3 3 0 0 3 3 3 0 UDP-glucoronosyl and UDP-glucosyl transferase Myosin_head PF00063.16 EAZ51542.1 - 8.1e-199 662.0 1.7 8.1e-199 662.0 1.2 2.0 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.14 EAZ51542.1 - 0.0017 17.9 0.0 0.0043 16.7 0.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.22 EAZ51542.1 - 0.0043 16.5 16.2 0.11 12.1 0.1 4.0 4 0 0 4 4 4 2 IQ calmodulin-binding motif Mnd1 PF03962.10 EAZ51542.1 - 0.0085 15.7 0.1 0.0085 15.7 0.1 5.6 2 2 2 5 5 5 2 Mnd1 family AAA_22 PF13401.1 EAZ51542.1 - 0.0092 16.1 2.8 0.31 11.1 0.0 3.8 4 0 0 4 4 4 1 AAA domain IncA PF04156.9 EAZ51542.1 - 0.03 13.9 69.6 0.039 13.5 6.7 4.9 2 1 2 4 4 4 0 IncA protein AAA_16 PF13191.1 EAZ51542.1 - 0.39 10.6 5.4 0.58 10.1 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain Ank_2 PF12796.2 EAZ51543.1 - 4.4e-41 139.1 2.6 1.5e-16 60.4 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAZ51543.1 - 5.7e-27 92.1 0.2 4.6e-07 29.3 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EAZ51543.1 - 2e-23 82.2 0.3 1.8e-06 28.2 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAZ51543.1 - 3.1e-21 74.8 0.8 6.6e-09 35.7 0.0 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAZ51543.1 - 8.1e-17 59.6 0.3 0.00014 21.7 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat WD40 PF00400.27 EAZ51544.1 - 1.6e-26 91.1 11.5 4.2e-07 29.6 0.3 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EAZ51544.1 - 0.00026 20.7 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ABC_membrane PF00664.18 EAZ51545.1 - 8.8e-75 251.6 34.5 2.5e-40 138.6 10.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAZ51545.1 - 1.2e-49 168.1 0.6 8.9e-34 116.7 0.1 2.9 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 EAZ51545.1 - 4e-08 32.6 0.5 0.0054 16.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EAZ51545.1 - 1.1e-07 31.3 3.1 0.0059 15.8 1.0 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EAZ51545.1 - 1.5e-07 31.6 0.1 0.0023 17.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EAZ51545.1 - 1.8e-07 31.3 8.3 2.3e-06 27.7 2.3 5.7 5 1 0 5 5 4 2 AAA domain DUF258 PF03193.11 EAZ51545.1 - 1.1e-06 27.8 0.1 0.014 14.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EAZ51545.1 - 1.8e-06 28.1 0.5 0.2 11.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EAZ51545.1 - 5.2e-06 27.2 0.0 0.034 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EAZ51545.1 - 6.1e-05 23.3 0.1 0.071 13.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EAZ51545.1 - 0.00012 21.9 0.6 0.022 14.7 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.15 EAZ51545.1 - 0.00017 20.4 0.5 0.029 13.0 0.1 2.5 2 0 0 2 2 2 1 G-protein alpha subunit Miro PF08477.8 EAZ51545.1 - 0.00041 20.8 0.0 1.2 9.6 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_30 PF13604.1 EAZ51545.1 - 0.0014 18.2 0.0 2.4 7.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EAZ51545.1 - 0.0019 18.5 12.5 0.16 12.3 0.3 3.8 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EAZ51545.1 - 0.0092 15.7 0.0 8.6 6.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EAZ51545.1 - 0.01 15.5 0.0 0.72 9.6 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain DUF3987 PF13148.1 EAZ51545.1 - 0.011 14.3 0.0 0.038 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF815 PF05673.8 EAZ51545.1 - 0.02 13.8 0.1 0.082 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.12 EAZ51545.1 - 0.024 14.4 1.6 2.3 7.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EAZ51545.1 - 0.044 13.2 2.0 6.5 6.1 0.0 2.7 2 1 0 2 2 2 0 AAA-like domain NACHT PF05729.7 EAZ51545.1 - 0.05 13.2 0.0 10 5.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.20 EAZ51545.1 - 0.05 13.1 0.0 0.95 8.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 EAZ51545.1 - 0.051 13.7 0.1 16 5.7 0.3 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EAZ51545.1 - 0.053 12.6 0.0 3.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 EAZ51545.1 - 0.07 12.8 0.1 0.67 9.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EAZ51545.1 - 0.13 12.1 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EAZ51545.1 - 0.18 11.7 0.1 22 4.9 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EAZ51545.1 - 0.31 10.4 2.4 11 5.3 0.1 2.5 2 1 0 2 2 2 0 AAA domain DUF3588 PF12140.3 EAZ51547.1 - 0.07 13.2 1.6 0.8 9.7 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3588) RNase_H PF00075.19 EAZ51547.1 - 0.31 11.3 5.7 0.12 12.7 1.4 2.2 2 0 0 2 2 2 0 RNase H DUF4140 PF13600.1 EAZ51547.1 - 3 8.3 25.0 0.059 13.8 2.2 4.7 3 2 1 5 5 5 0 N-terminal domain of unknown function (DUF4140) Filament PF00038.16 EAZ51547.1 - 7.5 5.9 52.4 0.15 11.4 17.6 3.4 2 1 0 3 3 3 0 Intermediate filament protein Acylphosphatase PF00708.13 EAZ51548.1 - 1.4e-21 76.3 0.0 1.9e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Acylphosphatase Pkinase PF00069.20 EAZ51549.1 - 8.3e-32 110.3 2.8 2e-15 56.6 2.7 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51549.1 - 3.8e-15 55.6 0.4 4.8e-08 32.4 0.4 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51549.1 - 5.1e-05 22.3 0.0 0.23 10.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.4 EAZ51549.1 - 0.075 12.3 0.1 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Tfb4 PF03850.9 EAZ51550.1 - 3.6e-28 98.5 6.5 8.6e-28 97.3 4.2 1.7 1 1 0 1 1 1 1 Transcription factor Tfb4 WSS_VP PF12175.3 EAZ51550.1 - 0.051 12.6 0.0 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 White spot syndrome virus structural envelope protein VP Mannosyl_trans2 PF04188.8 EAZ51551.1 - 9.4e-37 126.9 50.9 1.2e-36 126.5 35.3 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) ABC2_membrane PF01061.19 EAZ51552.1 - 3.2e-34 117.9 21.1 3.2e-34 117.9 14.6 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EAZ51552.1 - 8.1e-24 84.4 0.0 1.4e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAZ51552.1 - 9.2e-10 38.9 9.2 0.00019 21.4 0.1 3.3 2 1 1 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 EAZ51552.1 - 1.6e-07 30.7 22.1 1.6e-07 30.7 15.3 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.14 EAZ51552.1 - 2.6e-06 26.8 0.4 0.0089 15.2 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EAZ51552.1 - 1.8e-05 25.5 0.0 3.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAZ51552.1 - 0.00021 21.3 0.0 0.00043 20.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 EAZ51552.1 - 0.00023 21.0 0.0 0.00053 19.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EAZ51552.1 - 0.00031 20.2 0.1 0.00068 19.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EAZ51552.1 - 0.00046 19.6 0.1 0.036 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EAZ51552.1 - 0.00049 20.4 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EAZ51552.1 - 0.00049 19.3 0.1 0.00087 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EAZ51552.1 - 0.00065 20.0 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EAZ51552.1 - 0.0039 16.0 0.0 0.0067 15.2 0.0 1.3 1 0 0 1 1 1 1 ArgK protein NTPase_1 PF03266.10 EAZ51552.1 - 0.006 16.3 0.1 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_15 PF13175.1 EAZ51552.1 - 0.01 14.9 5.0 0.39 9.7 0.0 3.0 3 1 1 4 4 4 0 AAA ATPase domain T2SE PF00437.15 EAZ51552.1 - 0.016 14.1 0.1 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 EAZ51552.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EAZ51552.1 - 0.023 14.1 0.2 0.046 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain IglC PF11550.3 EAZ51552.1 - 0.026 13.8 0.4 0.055 12.7 0.2 1.4 1 0 0 1 1 1 0 Intracellular growth locus C protein AAA_30 PF13604.1 EAZ51552.1 - 0.045 13.3 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EAZ51552.1 - 0.051 13.7 0.0 0.29 11.3 0.0 2.3 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAZ51552.1 - 0.056 13.5 0.1 0.2 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAZ51552.1 - 0.061 13.0 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 1 0 Part of AAA domain AAA_33 PF13671.1 EAZ51552.1 - 0.098 12.5 0.0 0.28 11.0 0.1 1.7 2 0 0 2 2 1 0 AAA domain cobW PF02492.14 EAZ51552.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EAZ51552.1 - 0.1 12.4 0.2 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Dynamin family IstB_IS21 PF01695.12 EAZ51552.1 - 0.11 11.8 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.1 EAZ51552.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 EAZ51552.1 - 0.16 10.5 0.1 0.29 9.6 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class NACHT PF05729.7 EAZ51552.1 - 0.21 11.2 0.7 0.35 10.5 0.1 1.7 2 0 0 2 2 1 0 NACHT domain Ank_2 PF12796.2 EAZ51553.1 - 1.8e-55 185.2 3.3 4.5e-24 84.6 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAZ51553.1 - 2.6e-41 139.2 2.3 1.4e-13 50.8 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 EAZ51553.1 - 3e-31 105.6 0.0 6.6e-07 28.8 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EAZ51553.1 - 2.1e-25 88.1 0.3 1.5e-10 40.9 0.0 4.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAZ51553.1 - 1.4e-24 83.7 0.8 5e-05 23.1 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Sulfate_transp PF00916.15 EAZ51554.1 - 9.3e-35 119.9 14.7 2.1e-19 69.6 2.4 2.6 2 0 0 2 2 2 2 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EAZ51554.1 - 5.1e-19 67.7 1.9 5.1e-19 67.7 1.3 1.9 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EAZ51554.1 - 2e-10 40.0 0.1 6.6e-10 38.4 0.1 2.0 1 1 0 1 1 1 1 STAS domain cNMP_binding PF00027.24 EAZ51555.1 - 2.3e-45 152.3 0.0 2.2e-24 85.0 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Methyltransf_4 PF02390.12 EAZ51556.1 - 6.5e-48 162.4 0.0 7.8e-48 162.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EAZ51556.1 - 1.6e-05 25.4 0.0 2.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EAZ51556.1 - 9.2e-05 21.8 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EAZ51556.1 - 0.00013 21.9 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAZ51556.1 - 0.0028 17.2 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAZ51556.1 - 0.0074 15.6 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EAZ51556.1 - 0.0075 16.6 0.0 0.016 15.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 EAZ51556.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 EAZ51556.1 - 0.029 14.8 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EAZ51556.1 - 0.034 14.6 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EAZ51556.1 - 0.079 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_23 PF13489.1 EAZ51556.1 - 0.086 12.5 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.15 EAZ51556.1 - 0.087 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ras PF00071.17 EAZ51557.1 - 9.6e-51 171.3 0.0 1.2e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAZ51557.1 - 1.3e-16 61.1 0.0 2.6e-16 60.1 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EAZ51557.1 - 2.6e-12 46.3 0.0 3.3e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EAZ51557.1 - 0.00081 19.5 0.3 0.01 15.9 0.1 2.4 1 1 1 2 2 2 1 RNA helicase Gtr1_RagA PF04670.7 EAZ51557.1 - 0.0038 16.4 0.0 0.0049 16.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAZ51557.1 - 0.0096 15.8 0.0 0.021 14.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAZ51557.1 - 0.012 15.0 0.5 0.26 10.7 0.3 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EAZ51557.1 - 0.021 15.1 0.1 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter G-alpha PF00503.15 EAZ51557.1 - 0.025 13.2 0.1 1.9 7.1 0.0 2.8 2 1 1 3 3 3 0 G-protein alpha subunit NB-ARC PF00931.17 EAZ51557.1 - 0.028 13.2 0.0 0.093 11.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.1 EAZ51557.1 - 0.03 14.4 0.4 0.17 12.0 0.2 2.2 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 EAZ51557.1 - 0.082 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein MobB PF03205.9 EAZ51557.1 - 0.12 12.0 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EAZ51557.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.20 EAZ51558.1 - 1.8e-62 210.8 0.0 2.3e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51558.1 - 6.2e-32 110.6 0.0 8.7e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51558.1 - 0.026 13.4 0.0 0.046 12.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like OHA PF14418.1 EAZ51559.1 - 2.4e-25 87.8 0.0 5.2e-25 86.7 0.0 1.6 1 0 0 1 1 1 1 OST-HTH Associated domain OST-HTH PF12872.2 EAZ51559.1 - 0.0012 18.6 0.9 0.0068 16.2 0.1 2.5 2 0 0 2 2 2 1 OST-HTH/LOTUS domain Pkinase PF00069.20 EAZ51560.1 - 2.1e-67 227.0 0.0 2.4e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51560.1 - 1e-31 109.9 0.0 2e-31 109.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51560.1 - 1.2e-05 24.4 0.0 1.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAZ51560.1 - 0.08 11.9 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 EAZ51561.1 - 6.2e-35 117.8 12.2 1.7e-09 37.2 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EAZ51561.1 - 0.015 14.0 1.2 0.11 11.3 0.4 2.1 2 0 0 2 2 2 0 Coatomer WD associated region PIG-L PF02585.12 EAZ51562.1 - 5.7e-30 104.4 0.0 6.7e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Patched PF02460.13 EAZ51563.1 - 3.3e-95 319.6 37.3 2.2e-65 221.0 8.0 3.4 4 0 0 4 4 4 3 Patched family Sterol-sensing PF12349.3 EAZ51563.1 - 2e-30 105.2 3.5 2e-30 105.2 2.5 3.0 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 EAZ51563.1 - 0.08 10.3 11.9 0.13 9.6 8.3 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family RNase_T PF00929.19 EAZ51564.1 - 2.4e-13 50.7 0.0 3.7e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF4448 PF14610.1 EAZ51564.1 - 0.016 14.7 2.0 0.51 9.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) zf-SNAP50_C PF12251.3 EAZ51565.1 - 3.1e-51 173.5 6.8 5.1e-51 172.8 4.7 1.4 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Atrophin-1 PF03154.10 EAZ51565.1 - 0.87 7.6 4.3 1.1 7.3 2.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF948 PF06103.6 EAZ51566.1 - 0.0027 17.5 1.9 0.0027 17.5 1.3 8.8 4 4 4 9 9 9 4 Bacterial protein of unknown function (DUF948) Pkinase PF00069.20 EAZ51567.1 - 2.1e-39 135.2 0.0 3.5e-38 131.2 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51567.1 - 1.7e-12 46.9 0.0 4.7e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAZ51567.1 - 0.0012 18.6 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAZ51567.1 - 0.02 14.4 0.3 0.02 14.4 0.2 1.9 2 1 0 2 2 2 0 Choline/ethanolamine kinase dCMP_cyt_deam_1 PF00383.17 EAZ51568.1 - 7.8e-12 44.7 0.0 1.7e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region TPR_1 PF00515.23 EAZ51569.1 - 6e-09 35.1 1.2 3e-05 23.4 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAZ51569.1 - 1.7e-08 33.9 0.4 2.1e-08 33.6 0.3 1.1 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EAZ51569.1 - 1.6e-07 30.6 0.1 0.00044 19.9 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EAZ51569.1 - 6.1e-06 26.2 0.9 8.6e-06 25.8 0.6 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EAZ51569.1 - 3.1e-05 24.2 0.2 0.00017 21.8 0.2 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAZ51569.1 - 4.2e-05 24.0 0.0 5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAZ51569.1 - 0.00011 21.7 1.4 0.005 16.5 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAZ51569.1 - 0.00011 22.1 0.2 0.00077 19.4 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAZ51569.1 - 0.00058 20.2 0.0 0.002 18.6 0.0 1.7 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAZ51569.1 - 0.0026 17.6 1.6 0.057 13.3 0.4 2.1 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 EAZ51569.1 - 0.0072 16.1 0.0 0.0089 15.8 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EAZ51569.1 - 0.014 15.8 0.1 0.032 14.7 0.1 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_15 PF13429.1 EAZ51569.1 - 0.018 14.0 0.0 0.023 13.7 0.0 1.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAZ51569.1 - 0.029 14.2 0.2 0.065 13.1 0.1 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat Cbl_N PF02262.11 EAZ51569.1 - 0.11 12.2 0.2 3.9 7.1 0.0 2.0 1 1 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 tRNA-synt_2 PF00152.15 EAZ51570.1 - 1.1e-77 261.1 0.0 1.6e-77 260.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EAZ51570.1 - 4.8e-05 23.1 0.1 8.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EAZ51570.1 - 4.8e-05 22.6 0.1 0.11 11.6 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Peptidase_S49_N PF08496.5 EAZ51570.1 - 0.067 12.9 3.2 0.1 12.3 2.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AUX_IAA PF02309.11 EAZ51570.1 - 0.36 10.5 3.1 19 4.8 0.0 2.3 2 0 0 2 2 2 0 AUX/IAA family UDG PF03167.14 EAZ51571.1 - 2.3e-12 46.6 0.0 3.7e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily FAM124 PF15067.1 EAZ51571.1 - 0.017 14.5 0.1 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 FAM124 family DUF2989 PF11207.3 EAZ51571.1 - 0.13 11.6 1.5 0.2 11.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) Ras PF00071.17 EAZ51572.1 - 8e-57 191.1 0.1 9.6e-57 190.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAZ51572.1 - 3.4e-19 69.4 0.0 6.2e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAZ51572.1 - 4.3e-12 45.6 0.0 5.4e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAZ51572.1 - 4e-07 29.4 0.1 7.2e-07 28.5 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAZ51572.1 - 2.1e-06 27.6 0.0 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAZ51572.1 - 2.6e-05 23.7 0.0 0.00033 20.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EAZ51572.1 - 0.00082 18.5 0.1 0.0012 18.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EAZ51572.1 - 0.0014 18.7 0.0 0.0024 18.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EAZ51572.1 - 0.0031 16.9 0.2 0.024 14.0 0.1 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EAZ51572.1 - 0.0035 17.3 0.1 0.035 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 EAZ51572.1 - 0.007 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EAZ51572.1 - 0.0074 16.0 0.5 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 EAZ51572.1 - 0.0084 15.5 0.0 0.019 14.4 0.0 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EAZ51572.1 - 0.0094 14.9 0.1 0.027 13.5 0.0 1.7 2 0 0 2 2 2 1 Septin SRPRB PF09439.5 EAZ51572.1 - 0.019 14.2 0.1 0.052 12.7 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EAZ51572.1 - 0.022 14.2 0.1 0.087 12.3 0.1 1.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EAZ51572.1 - 0.039 13.5 0.2 2.1 7.7 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 EAZ51572.1 - 0.054 13.2 0.1 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EAZ51572.1 - 0.09 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EAZ51572.1 - 0.092 12.4 0.0 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EAZ51572.1 - 0.092 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 EAZ51572.1 - 0.17 12.1 0.5 0.29 11.4 0.3 1.7 1 1 0 1 1 1 0 ABC transporter HhH-GPD PF00730.20 EAZ51573.1 - 2.4e-21 76.0 0.0 3.1e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EAZ51573.1 - 3.2e-07 29.6 0.0 1e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 EAZ51573.1 - 0.00051 20.1 4.0 0.00081 19.4 2.7 1.3 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.1 EAZ51573.1 - 0.0033 17.5 0.0 0.3 11.2 0.0 1.7 1 1 1 2 2 2 2 Helix-hairpin-helix domain HHH_3 PF12836.2 EAZ51573.1 - 0.13 12.1 0.1 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif Slu7 PF11708.3 EAZ51574.1 - 1.4e-66 224.6 12.7 1.9e-66 224.2 8.8 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.18 EAZ51574.1 - 0.0031 17.3 0.5 0.0062 16.4 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EAZ51574.1 - 0.0033 17.0 0.5 0.0085 15.7 0.3 1.7 1 0 0 1 1 1 1 Zinc knuckle TIP49 PF06068.8 EAZ51575.1 - 9.5e-177 587.6 0.4 1.1e-176 587.4 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EAZ51575.1 - 1.3e-12 48.1 0.0 3.4e-08 33.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAZ51575.1 - 4e-09 35.8 1.4 2.1e-06 26.9 0.0 3.0 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EAZ51575.1 - 1.7e-08 34.6 0.0 0.0069 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EAZ51575.1 - 9.3e-08 32.2 0.0 7.8e-06 25.9 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EAZ51575.1 - 6.6e-06 25.8 0.0 0.00071 19.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EAZ51575.1 - 8.5e-06 25.4 0.0 2.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EAZ51575.1 - 9.5e-05 22.3 0.0 0.55 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EAZ51575.1 - 0.00014 21.3 0.1 0.041 13.3 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EAZ51575.1 - 0.00017 20.8 0.2 0.0058 15.8 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EAZ51575.1 - 0.00019 22.2 0.0 0.00035 21.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAZ51575.1 - 0.00042 20.6 0.0 0.0016 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EAZ51575.1 - 0.0007 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EAZ51575.1 - 0.00085 18.7 0.1 0.0018 17.7 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EAZ51575.1 - 0.00097 18.2 0.1 0.0017 17.5 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EAZ51575.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 EAZ51575.1 - 0.0024 16.7 0.0 0.0042 15.9 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EAZ51575.1 - 0.0094 16.0 0.0 0.079 13.0 0.0 2.3 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_23 PF13476.1 EAZ51575.1 - 0.0098 16.2 0.0 0.017 15.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAZ51575.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EAZ51575.1 - 0.013 15.0 0.1 0.12 11.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain UPF0079 PF02367.12 EAZ51575.1 - 0.019 14.5 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EAZ51575.1 - 0.022 14.5 0.2 0.099 12.3 0.0 2.2 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.22 EAZ51575.1 - 0.024 14.9 0.0 0.18 12.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter KaiC PF06745.8 EAZ51575.1 - 0.027 13.5 0.1 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_2 PF07724.9 EAZ51575.1 - 0.031 14.1 0.2 0.28 11.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) NACHT PF05729.7 EAZ51575.1 - 0.037 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EAZ51575.1 - 0.046 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 EAZ51575.1 - 0.058 12.6 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 EAZ51575.1 - 0.062 12.2 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EAZ51575.1 - 0.063 12.8 0.0 0.09 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 EAZ51575.1 - 0.077 11.9 0.0 8.1 5.2 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Rad17 PF03215.10 EAZ51575.1 - 0.084 11.5 0.0 0.18 10.4 0.0 1.5 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 EAZ51575.1 - 0.1 12.1 0.1 0.62 9.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain XPG_N PF00752.12 EAZ51576.1 - 2.5e-29 101.5 0.0 5.3e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EAZ51576.1 - 1.5e-28 98.7 0.4 5.6e-28 96.8 0.0 2.2 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 EAZ51576.1 - 1.9e-07 31.2 0.0 1.1e-06 28.8 0.0 2.3 1 1 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.11 EAZ51576.1 - 0.0049 16.2 0.0 0.014 14.7 0.0 1.8 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain HHH_2 PF12826.2 EAZ51576.1 - 0.015 15.1 0.1 0.051 13.4 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif CDKN3 PF05706.7 EAZ51576.1 - 0.041 13.3 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) EMP24_GP25L PF01105.19 EAZ51577.1 - 5.2e-29 101.2 6.0 6e-29 101.0 4.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Filamin PF00630.14 EAZ51577.1 - 0.018 15.5 1.2 0.035 14.6 0.2 1.8 2 0 0 2 2 2 0 Filamin/ABP280 repeat Fcf1 PF04900.7 EAZ51578.1 - 2.1e-39 133.6 0.7 2.6e-39 133.3 0.5 1.1 1 0 0 1 1 1 1 Fcf1 Skp1 PF01466.14 EAZ51579.1 - 3.7e-37 126.2 2.7 5.2e-37 125.7 1.8 1.2 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EAZ51579.1 - 5.2e-17 61.6 0.0 1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Abhydrolase_5 PF12695.2 EAZ51580.1 - 6.3e-14 51.9 0.0 7.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAZ51580.1 - 4.5e-10 39.8 0.0 5.3e-09 36.2 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAZ51580.1 - 1.8e-06 27.7 0.0 2.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EAZ51580.1 - 5.4e-06 26.1 0.7 0.00039 20.0 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EAZ51580.1 - 8.2e-05 22.1 0.1 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EAZ51580.1 - 0.13 11.5 0.0 1.1 8.4 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Metallophos PF00149.23 EAZ51581.1 - 3e-45 154.0 1.0 3.7e-45 153.8 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Bromodomain PF00439.20 EAZ51582.1 - 8.6e-21 73.6 0.7 3.2e-20 71.8 0.5 2.1 1 0 0 1 1 1 1 Bromodomain UQ_con PF00179.21 EAZ51583.1 - 8.2e-39 132.2 0.1 8.8e-39 132.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAZ51583.1 - 0.00043 20.0 0.0 0.00047 19.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B BRE PF06113.7 EAZ51583.1 - 0.13 11.3 0.7 0.4 9.6 0.1 1.8 2 0 0 2 2 2 0 Brain and reproductive organ-expressed protein (BRE) UQ_con PF00179.21 EAZ51584.1 - 8.8e-45 151.5 0.1 1e-44 151.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAZ51584.1 - 1.2e-05 25.0 0.0 1.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EAZ51584.1 - 0.013 15.3 0.9 0.025 14.4 0.6 1.8 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 EAZ51584.1 - 0.091 12.4 0.1 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.20 EAZ51585.1 - 7.2e-49 166.2 0.0 1.3e-46 158.8 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51585.1 - 9.5e-25 87.1 0.0 1.5e-16 60.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51585.1 - 5.4e-08 32.1 0.0 7e-05 21.9 0.0 2.2 1 1 1 2 2 2 2 Kinase-like S1-P1_nuclease PF02265.11 EAZ51586.1 - 5.4e-20 72.0 0.0 6.7e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF161 PF02588.10 EAZ51586.1 - 0.049 13.9 1.9 0.11 12.8 1.3 1.5 1 0 0 1 1 1 0 Uncharacterized BCR, YitT family COG1284 DNA_RNApol_7kD PF03604.8 EAZ51587.1 - 1.1e-16 60.0 5.9 1.3e-16 59.7 4.1 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 EAZ51587.1 - 0.0091 15.7 0.9 0.011 15.5 0.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 EAZ51587.1 - 0.013 15.1 0.9 0.013 15.1 0.6 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF2757 PF10955.3 EAZ51587.1 - 0.04 14.1 0.3 0.052 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) GFA PF04828.9 EAZ51587.1 - 0.078 12.9 3.1 0.79 9.7 0.3 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme ZF-HD_dimer PF04770.7 EAZ51587.1 - 0.096 12.7 1.1 0.11 12.5 0.7 1.1 1 0 0 1 1 1 0 ZF-HD protein dimerisation region Zn-ribbon_8 PF09723.5 EAZ51587.1 - 0.16 11.9 2.7 0.26 11.2 1.8 1.4 1 1 0 1 1 1 0 Zinc ribbon domain DUF2296 PF10058.4 EAZ51587.1 - 0.38 10.5 0.0 0.38 10.5 0.0 2.0 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) DUF2688 PF10892.3 EAZ51587.1 - 0.55 9.9 6.1 0.69 9.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) zf-ISL3 PF14690.1 EAZ51587.1 - 0.56 10.2 8.4 0.38 10.8 2.5 2.0 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-NADH-PPase PF09297.6 EAZ51587.1 - 0.63 9.6 5.5 0.94 9.0 3.8 1.2 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EAZ51587.1 - 0.67 9.8 6.3 0.71 9.7 1.2 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.1 EAZ51587.1 - 1 9.7 4.3 3.7 7.9 0.1 2.0 1 1 1 2 2 2 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.6 EAZ51587.1 - 2.5 7.8 5.2 0.57 9.8 1.3 1.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Chordopox_RPO7 PF05864.7 EAZ51587.1 - 3.3 7.8 5.2 6.8 6.8 0.2 2.1 1 1 1 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Helicase_C_2 PF13307.1 EAZ51588.1 - 3.5e-45 153.9 0.1 1.1e-44 152.4 0.1 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EAZ51588.1 - 6.7e-35 120.0 10.0 6.7e-35 120.0 7.0 2.2 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.24 EAZ51588.1 - 0.0054 16.2 0.0 0.037 13.5 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EAZ51588.1 - 0.01 15.7 4.9 0.093 12.5 0.8 3.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Pkinase PF00069.20 EAZ51589.1 - 3.7e-61 206.5 0.0 4.1e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51589.1 - 5.3e-35 120.7 0.0 6.2e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51589.1 - 1.5e-08 33.9 0.0 2.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAZ51589.1 - 0.0039 16.9 0.0 0.094 12.4 0.1 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EAZ51590.1 - 2e-72 243.4 0.1 2.4e-72 243.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51590.1 - 2.2e-38 131.7 0.0 2.9e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51590.1 - 6.4e-06 25.3 0.0 0.0002 20.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EAZ51590.1 - 0.0055 15.7 0.1 0.0082 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAZ51590.1 - 0.026 14.2 0.1 0.23 11.1 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family WD40 PF00400.27 EAZ51591.1 - 2e-44 147.9 15.0 1.7e-10 40.3 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EAZ51591.1 - 1.3e-05 23.6 4.1 0.1 10.6 0.0 4.4 1 1 4 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EAZ51591.1 - 0.00013 20.8 5.6 0.33 9.6 0.0 4.4 1 1 2 4 4 4 2 Nup133 N terminal like Ricin_B_lectin PF00652.17 EAZ51591.1 - 0.0064 16.5 0.2 1.6 8.7 0.1 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain PQQ_2 PF13360.1 EAZ51591.1 - 0.016 14.6 0.0 5.4 6.4 0.0 2.5 2 1 1 3 3 3 0 PQQ-like domain SBBP PF06739.6 EAZ51591.1 - 0.031 14.0 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Beta-propeller repeat RED_C PF07807.6 EAZ51591.1 - 0.051 13.7 0.1 24 5.1 0.0 3.5 3 2 1 4 4 4 0 RED-like protein C-terminal region LSM PF01423.17 EAZ51592.1 - 1.1e-16 60.1 1.2 1.2e-16 59.9 0.8 1.0 1 0 0 1 1 1 1 LSM domain Atg8 PF02991.11 EAZ51593.1 - 2.7e-31 107.6 2.1 8.6e-30 102.7 1.5 2.0 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EAZ51593.1 - 9.6e-06 25.7 1.2 0.0003 20.9 0.8 2.0 1 1 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 RCC1_2 PF13540.1 EAZ51594.1 - 0.00044 19.7 1.7 0.26 10.9 0.0 3.9 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat MANEC PF07502.9 EAZ51594.1 - 0.012 15.5 0.2 0.041 13.8 0.1 1.9 1 0 0 1 1 1 0 MANEC domain ArsA_ATPase PF02374.10 EAZ51595.1 - 7e-87 291.2 1.1 1.3e-82 277.2 0.1 2.0 1 1 1 2 2 2 2 Anion-transporting ATPase CbiA PF01656.18 EAZ51595.1 - 1.3e-13 50.7 0.0 3.2e-13 49.5 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EAZ51595.1 - 2e-07 31.1 0.0 1.9e-06 27.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EAZ51595.1 - 1.1e-05 24.7 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EAZ51595.1 - 0.0006 19.3 0.0 0.0029 17.0 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EAZ51595.1 - 0.00062 19.4 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 EAZ51595.1 - 0.021 13.6 0.0 0.048 12.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 EAZ51595.1 - 0.022 14.1 0.1 0.057 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAZ51595.1 - 0.033 14.4 0.0 0.08 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAZ51595.1 - 0.035 13.1 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 EAZ51595.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 EAZ51595.1 - 0.083 13.7 0.0 0.25 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain MipZ PF09140.6 EAZ51595.1 - 0.12 11.3 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 ATPase MipZ IstB_IS21 PF01695.12 EAZ51595.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Clat_adaptor_s PF01217.15 EAZ51596.1 - 2.9e-06 27.0 0.0 3.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SecE PF00584.15 EAZ51597.1 - 6.9e-12 44.7 0.0 8.6e-12 44.4 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DZR PF12773.2 EAZ51598.1 - 0.041 13.6 0.8 0.07 12.9 0.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 EAZ51598.1 - 0.049 13.1 1.1 0.12 11.8 0.8 1.7 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 EAZ51598.1 - 0.088 12.0 2.0 0.14 11.4 1.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain RNA_pol_L_2 PF13656.1 EAZ51599.1 - 6.7e-23 79.9 0.0 9.4e-23 79.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EAZ51599.1 - 1.3e-06 27.3 0.0 1.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ras PF00071.17 EAZ51600.1 - 5.4e-51 172.1 0.0 6.2e-51 171.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAZ51600.1 - 9.7e-17 61.5 0.0 1.6e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAZ51600.1 - 1.5e-14 53.6 0.0 1.8e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAZ51600.1 - 5.8e-07 28.8 0.0 6.9e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EAZ51600.1 - 9.4e-05 21.9 0.1 0.00041 19.8 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EAZ51600.1 - 0.00018 21.4 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EAZ51600.1 - 0.0063 16.6 0.0 0.026 14.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.5 EAZ51600.1 - 0.0091 15.2 0.0 0.026 13.7 0.0 1.7 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EAZ51601.1 - 4.2e-52 176.0 0.1 1.8e-27 96.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAZ51601.1 - 3.8e-34 118.3 29.2 6.2e-28 97.9 6.2 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EAZ51601.1 - 1.5e-07 30.8 10.4 0.0083 15.3 0.2 4.2 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EAZ51601.1 - 2.4e-05 23.7 0.5 0.08 12.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EAZ51601.1 - 0.0006 20.2 1.1 0.57 10.6 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EAZ51601.1 - 0.0013 18.6 0.0 0.35 10.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EAZ51601.1 - 0.011 14.8 0.4 2 7.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 EAZ51601.1 - 0.012 14.5 0.1 0.31 9.9 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EAZ51601.1 - 0.013 14.9 0.1 0.98 8.8 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EAZ51601.1 - 0.019 15.7 0.2 4.5 8.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EAZ51601.1 - 0.024 13.7 0.5 1.6 7.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EAZ51601.1 - 0.052 13.8 7.3 1.2 9.4 0.1 3.5 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EAZ51601.1 - 0.07 12.5 0.0 10 5.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EAZ51601.1 - 0.07 12.8 1.3 5.6 6.6 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EAZ51601.1 - 0.1 12.3 3.6 1.8 8.3 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 cobW PF02492.14 EAZ51601.1 - 0.12 11.8 0.6 0.75 9.2 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EAZ51601.1 - 0.23 11.4 3.2 1.2 9.0 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 EAZ51601.1 - 0.36 10.3 0.4 52 3.3 0.1 2.9 3 0 0 3 3 3 0 AAA domain ubiquitin PF00240.18 EAZ51602.1 - 1.9e-23 81.6 0.9 2.1e-23 81.5 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EAZ51602.1 - 1.7e-14 53.2 0.7 1.9e-14 53.0 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EAZ51602.1 - 7.5e-05 22.9 0.3 0.00021 21.4 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EAZ51602.1 - 0.00049 19.9 0.1 0.001 18.9 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.3 EAZ51602.1 - 0.054 13.4 0.2 0.2 11.6 0.0 1.8 1 1 1 2 2 2 0 GLUT4 regulating protein TUG Prefoldin_2 PF01920.15 EAZ51603.1 - 9.7e-23 79.9 4.8 1.2e-22 79.6 3.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EAZ51603.1 - 0.00019 21.0 6.8 0.0017 18.0 4.7 1.9 1 1 0 1 1 1 1 Prefoldin subunit GAS PF13851.1 EAZ51603.1 - 0.00062 19.0 3.4 0.00092 18.4 2.3 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4140 PF13600.1 EAZ51603.1 - 0.0024 18.2 0.5 0.38 11.2 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) DUF4600 PF15372.1 EAZ51603.1 - 0.0031 17.7 3.4 0.011 15.9 2.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4600) DUF677 PF05055.7 EAZ51603.1 - 0.0034 16.1 2.3 0.11 11.1 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF677) DUF2051 PF09738.4 EAZ51603.1 - 0.004 16.4 3.3 0.0051 16.1 2.3 1.1 1 0 0 1 1 1 1 Double stranded RNA binding protein (DUF2051) Spc7 PF08317.6 EAZ51603.1 - 0.0044 15.7 3.7 0.19 10.3 0.6 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein Med4 PF10018.4 EAZ51603.1 - 0.0063 15.9 1.2 0.0063 15.9 0.9 2.0 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 NPV_P10 PF05531.7 EAZ51603.1 - 0.0099 16.1 1.0 1.9 8.7 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 EAZ51603.1 - 0.011 15.4 9.6 0.027 14.1 2.1 2.0 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Lectin_N PF03954.9 EAZ51603.1 - 0.013 14.9 0.4 0.019 14.3 0.3 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.7 EAZ51603.1 - 0.013 15.2 0.3 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATP-synt_D PF01813.12 EAZ51603.1 - 0.014 14.9 2.0 0.19 11.2 0.3 2.0 2 0 0 2 2 2 0 ATP synthase subunit D TMF_DNA_bd PF12329.3 EAZ51603.1 - 0.015 15.0 15.8 0.26 11.0 1.5 2.6 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding Sec8_exocyst PF04048.9 EAZ51603.1 - 0.019 14.6 2.1 1.6 8.3 0.1 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain SlyX PF04102.7 EAZ51603.1 - 0.02 15.2 2.1 2.8 8.3 0.1 2.2 2 0 0 2 2 2 0 SlyX MbeD_MobD PF04899.7 EAZ51603.1 - 0.021 14.7 0.5 2.9 7.8 0.0 2.5 3 0 0 3 3 2 0 MbeD/MobD like Filament PF00038.16 EAZ51603.1 - 0.022 14.2 2.4 0.3 10.5 0.1 2.0 2 0 0 2 2 2 0 Intermediate filament protein Ax_dynein_light PF10211.4 EAZ51603.1 - 0.022 14.6 4.2 0.53 10.0 0.8 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain HAUS4 PF14735.1 EAZ51603.1 - 0.023 13.9 1.8 2.9 7.1 0.0 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 IncA PF04156.9 EAZ51603.1 - 0.024 14.2 9.8 0.11 12.0 6.8 1.8 1 1 0 1 1 1 0 IncA protein DASH_Dad3 PF08656.5 EAZ51603.1 - 0.024 14.2 1.7 1.8 8.3 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 Mnd1 PF03962.10 EAZ51603.1 - 0.025 14.2 4.4 0.14 11.8 3.0 1.8 1 1 0 1 1 1 0 Mnd1 family DUF1041 PF06292.12 EAZ51603.1 - 0.03 14.4 0.2 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) KCNQ_channel PF03520.9 EAZ51603.1 - 0.034 13.4 1.3 0.039 13.2 0.2 1.6 2 0 0 2 2 2 0 KCNQ voltage-gated potassium channel TMF_TATA_bd PF12325.3 EAZ51603.1 - 0.04 13.6 4.8 0.047 13.4 0.5 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FliD_C PF07195.7 EAZ51603.1 - 0.041 13.1 0.7 0.23 10.7 0.1 1.9 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF2802 PF10975.3 EAZ51603.1 - 0.043 13.5 0.3 2.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Syntaxin PF00804.20 EAZ51603.1 - 0.046 13.8 3.4 0.066 13.3 2.4 1.2 1 0 0 1 1 1 0 Syntaxin TBPIP PF07106.8 EAZ51603.1 - 0.047 13.2 5.6 0.44 10.0 0.7 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BRE1 PF08647.6 EAZ51603.1 - 0.048 13.6 4.7 0.089 12.7 0.8 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1319 PF07028.6 EAZ51603.1 - 0.055 13.6 2.3 4.1 7.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) DUF479 PF04336.7 EAZ51603.1 - 0.055 13.5 0.3 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF479 Laminin_II PF06009.7 EAZ51603.1 - 0.055 13.2 7.5 0.55 9.9 1.1 2.1 2 0 0 2 2 2 0 Laminin Domain II ApoLp-III PF07464.6 EAZ51603.1 - 0.058 13.4 0.6 0.058 13.4 0.4 1.6 2 0 0 2 2 1 0 Apolipophorin-III precursor (apoLp-III) MIS13 PF08202.6 EAZ51603.1 - 0.058 12.4 2.7 0.068 12.2 1.9 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Cep57_CLD_2 PF14197.1 EAZ51603.1 - 0.058 13.3 6.0 0.096 12.6 0.7 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Snf7 PF03357.16 EAZ51603.1 - 0.06 12.7 5.3 0.097 12.0 0.5 2.0 2 0 0 2 2 2 0 Snf7 Tropomyosin_1 PF12718.2 EAZ51603.1 - 0.062 13.1 6.9 0.12 12.2 1.5 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF948 PF06103.6 EAZ51603.1 - 0.073 12.9 0.9 0.6 10.0 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TSC22 PF01166.13 EAZ51603.1 - 0.073 13.0 4.8 0.19 11.7 0.8 2.4 2 1 0 2 2 2 0 TSC-22/dip/bun family TMP_2 PF06791.8 EAZ51603.1 - 0.074 12.6 0.1 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF4407 PF14362.1 EAZ51603.1 - 0.075 11.9 1.7 0.15 10.9 1.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4618 PF15397.1 EAZ51603.1 - 0.077 12.3 6.9 0.31 10.3 1.3 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) DUF3251 PF11622.3 EAZ51603.1 - 0.077 12.3 1.4 1 8.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) XhlA PF10779.4 EAZ51603.1 - 0.084 12.7 5.9 0.091 12.6 0.8 2.2 2 0 0 2 2 2 0 Haemolysin XhlA FlxA PF14282.1 EAZ51603.1 - 0.086 12.7 0.8 0.086 12.7 0.6 3.0 2 1 1 3 3 2 0 FlxA-like protein Nsp1_C PF05064.8 EAZ51603.1 - 0.091 12.4 1.2 1.6 8.4 0.1 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region Syntaxin-6_N PF09177.6 EAZ51603.1 - 0.092 13.1 1.7 0.57 10.6 0.2 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Laminin_I PF06008.9 EAZ51603.1 - 0.094 12.0 3.7 0.25 10.6 2.6 1.6 1 1 0 1 1 1 0 Laminin Domain I MutS_IV PF05190.13 EAZ51603.1 - 0.11 12.6 2.6 0.89 9.7 0.2 2.1 2 0 0 2 2 2 0 MutS family domain IV FliD_N PF02465.13 EAZ51603.1 - 0.13 12.6 4.4 0.89 9.9 0.9 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus PhoU PF01895.14 EAZ51603.1 - 0.14 12.6 1.8 0.27 11.7 0.1 2.0 2 1 0 2 2 2 0 PhoU domain CENP-F_leu_zip PF10473.4 EAZ51603.1 - 0.14 11.9 9.2 0.37 10.6 2.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CDC37_N PF03234.9 EAZ51603.1 - 0.16 12.3 4.0 0.26 11.5 2.8 1.3 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DivIC PF04977.10 EAZ51603.1 - 0.17 11.3 5.8 0.67 9.4 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF16 PF01519.11 EAZ51603.1 - 0.17 12.1 4.6 7.4 6.8 3.2 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 EMP24_GP25L PF01105.19 EAZ51603.1 - 0.18 11.5 1.3 0.65 9.6 0.1 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Vps51 PF08700.6 EAZ51603.1 - 0.18 11.6 3.6 6.2 6.7 0.1 2.5 2 1 0 2 2 2 0 Vps51/Vps67 DUF2229 PF09989.4 EAZ51603.1 - 0.18 11.2 0.7 0.23 10.8 0.4 1.3 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) AAA_23 PF13476.1 EAZ51603.1 - 0.2 11.9 3.0 0.28 11.4 2.1 1.2 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.1 EAZ51603.1 - 0.2 11.5 6.8 2.9 7.8 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF724 PF05266.9 EAZ51603.1 - 0.21 11.2 3.2 0.61 9.6 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ADIP PF11559.3 EAZ51603.1 - 0.21 11.4 5.3 0.58 10.0 0.5 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 EAZ51603.1 - 0.22 11.8 7.3 0.7 10.2 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) APG6 PF04111.7 EAZ51603.1 - 0.22 10.5 5.1 0.22 10.5 1.1 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EAZ51603.1 - 0.23 9.2 1.8 0.29 8.9 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MerR-DNA-bind PF09278.6 EAZ51603.1 - 0.23 11.8 1.5 3.5 8.0 0.0 2.2 2 0 0 2 2 2 0 MerR, DNA binding Not3 PF04065.10 EAZ51603.1 - 0.24 10.6 4.9 0.66 9.2 3.2 1.8 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Spc24 PF08286.6 EAZ51603.1 - 0.25 11.0 8.3 0.7 9.5 2.1 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 COG5 PF10392.4 EAZ51603.1 - 0.3 11.0 2.9 1.4 8.9 0.3 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 EAP30 PF04157.11 EAZ51603.1 - 0.31 10.1 3.1 1.6 7.8 0.1 2.1 2 0 0 2 2 2 0 EAP30/Vps36 family bZIP_1 PF00170.16 EAZ51603.1 - 0.31 11.0 8.9 5.8 6.9 2.5 2.7 2 1 0 2 2 2 0 bZIP transcription factor Tho2 PF11262.3 EAZ51603.1 - 0.32 9.9 3.7 1.7 7.6 0.1 2.0 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 CENP-Q PF13094.1 EAZ51603.1 - 0.38 10.7 8.5 0.34 10.9 2.3 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Lge1 PF11488.3 EAZ51603.1 - 0.43 10.7 4.2 0.44 10.7 0.5 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 ACCA PF03255.9 EAZ51603.1 - 0.44 10.1 2.2 1.7 8.1 0.3 2.0 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF342 PF03961.8 EAZ51603.1 - 0.49 8.7 5.8 1.7 6.9 3.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF3584 PF12128.3 EAZ51603.1 - 0.5 7.6 5.5 1.3 6.2 3.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) HAUS-augmin3 PF14932.1 EAZ51603.1 - 0.51 9.4 5.7 2.1 7.4 3.9 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Hormone_1 PF00103.15 EAZ51603.1 - 0.54 9.5 4.3 2 7.7 1.0 2.0 2 0 0 2 2 2 0 Somatotropin hormone family GrpE PF01025.14 EAZ51603.1 - 0.55 9.7 4.2 0.85 9.1 0.7 2.0 2 0 0 2 2 2 0 GrpE DUF972 PF06156.8 EAZ51603.1 - 0.6 10.4 3.8 4.9 7.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 EAZ51603.1 - 0.65 9.7 6.0 3.2 7.5 0.4 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) YlqD PF11068.3 EAZ51603.1 - 0.8 9.7 4.6 0.78 9.7 0.6 2.0 1 1 0 2 2 2 0 YlqD protein Fib_alpha PF08702.5 EAZ51603.1 - 0.81 9.7 6.0 5.1 7.2 0.5 2.0 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.17 EAZ51603.1 - 0.82 9.7 10.4 2 8.4 2.0 2.2 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AKNA PF12443.3 EAZ51603.1 - 1.1 9.2 3.8 5.3 7.1 0.1 2.7 2 1 1 3 3 3 0 AT-hook-containing transcription factor AAA_13 PF13166.1 EAZ51603.1 - 1.2 7.4 7.1 3.8 5.8 5.0 1.7 1 1 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 EAZ51603.1 - 1.3 9.2 6.2 13 6.0 0.1 2.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Allexi_40kDa PF05549.6 EAZ51603.1 - 1.5 8.0 5.6 2.7 7.2 0.8 2.1 1 1 0 2 2 2 0 Allexivirus 40kDa protein Uds1 PF15456.1 EAZ51603.1 - 1.8 8.6 7.8 9.6 6.2 1.0 2.1 1 1 1 2 2 2 0 Up-regulated During Septation HDV_ag PF01517.13 EAZ51603.1 - 2.1 7.9 5.2 5.2 6.7 0.3 2.0 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen Swi5 PF07061.6 EAZ51603.1 - 2.4 7.9 5.1 2.3 8.0 0.9 2.1 2 0 0 2 2 2 0 Swi5 CCDC-167 PF15188.1 EAZ51603.1 - 3.9 7.4 7.8 10 6.1 1.8 2.4 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Pox_A_type_inc PF04508.7 EAZ51603.1 - 5.1 7.1 11.0 9.6 6.2 1.0 4.1 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat Striatin PF08232.7 EAZ51603.1 - 6.6 7.0 7.9 1e+02 3.1 5.5 2.1 1 1 0 1 1 1 0 Striatin family FlaC_arch PF05377.6 EAZ51603.1 - 7 6.6 8.9 3.4 7.6 1.9 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Ribosomal_S4e PF00900.15 EAZ51604.1 - 2.2e-24 84.9 0.4 2.2e-24 84.9 0.3 1.9 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 EAZ51604.1 - 1.2e-20 73.1 2.2 2.2e-20 72.1 1.5 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EAZ51604.1 - 3.4e-08 32.7 0.0 6.1e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EAZ51604.1 - 0.00042 19.9 3.1 0.00098 18.7 0.1 3.2 3 0 0 3 3 3 1 KOW motif Pkinase PF00069.20 EAZ51605.1 - 3.8e-49 167.1 0.0 4.6e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51605.1 - 2.3e-26 92.4 0.0 3.2e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EAZ51605.1 - 0.0065 16.0 0.5 0.012 15.2 0.3 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EAZ51605.1 - 0.0079 15.2 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAZ51605.1 - 0.074 12.7 0.0 0.61 9.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-RING_2 PF13639.1 EAZ51606.1 - 0.31 10.9 3.0 1.5 8.7 2.1 2.2 1 1 0 1 1 1 0 Ring finger domain Pkinase PF00069.20 EAZ51608.1 - 1.5e-60 204.5 0.0 7.6e-60 202.2 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAZ51608.1 - 2.6e-38 131.5 0.0 6.1e-38 130.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAZ51608.1 - 2.1e-06 26.9 0.0 5.1e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAZ51608.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family