# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- UPF0051 PF01458.17 PFH30577.1 - 7.1e-43 146.8 0.0 9e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) RNA_pol_Rpb2_6 PF00562.28 PFH30578.1 - 3.4e-90 302.9 0.0 8.1e-90 301.7 0.0 1.6 1 1 1 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 PFH30578.1 - 7.5e-19 67.9 0.0 8.4e-18 64.6 0.0 2.5 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 PFH30578.1 - 2.9e-10 40.2 0.0 7.8e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb1_1 PF04997.12 PFH30579.1 - 1.4e-34 119.8 3.1 2.5e-33 115.7 3.1 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 PFH30579.1 - 2.9e-28 99.2 0.0 2.3e-22 80.0 0.0 2.4 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 PFH30580.1 - 9.2e-33 113.8 0.0 1.1e-32 113.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 PFH30580.1 - 4.1e-06 26.7 0.1 1.3e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Ribosomal_S2 PF00318.20 PFH30582.1 - 2.4e-19 69.4 4.0 2.8e-19 69.2 4.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 AAA_2 PF07724.14 PFH30585.1 - 1.2e-46 159.0 0.0 4.6e-46 157.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 PFH30585.1 - 1.3e-14 54.7 0.1 1.3e-08 35.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PFH30585.1 - 3e-14 53.2 0.0 2.1e-11 44.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 PFH30585.1 - 2.7e-11 43.3 0.0 7.7e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_lid_9 PF17871.1 PFH30585.1 - 9.7e-08 31.9 0.1 1.9e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain Sigma54_activat PF00158.26 PFH30585.1 - 2.4e-06 27.4 0.0 2e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain Torsin PF06309.11 PFH30585.1 - 1.1e-05 25.6 0.0 4e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 Torsin AAA_7 PF12775.7 PFH30585.1 - 0.00013 21.5 0.4 0.21 11.1 0.0 3.1 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_22 PF13401.6 PFH30585.1 - 0.00051 20.3 0.3 0.019 15.2 0.4 3.3 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 PFH30585.1 - 0.00056 19.8 1.5 0.63 9.9 0.4 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 PFH30585.1 - 0.0019 18.6 0.0 0.091 13.1 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 PFH30585.1 - 0.0019 18.7 0.2 0.015 15.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PFH30585.1 - 0.0022 17.7 0.2 0.2 11.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 PFH30585.1 - 0.0068 16.2 0.0 0.31 10.8 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 PFH30585.1 - 0.0076 15.4 0.1 1.1 8.4 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 PFH30585.1 - 0.013 15.7 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PFH30585.1 - 0.021 15.2 0.0 0.39 11.1 0.0 3.1 2 0 0 2 2 2 0 RNA helicase TniB PF05621.11 PFH30585.1 - 0.032 13.6 0.1 4.3 6.7 0.0 2.8 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 PFH30585.1 - 0.094 12.7 0.1 6.1 6.9 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 PFH30585.1 - 0.097 12.0 0.1 0.61 9.4 0.0 2.2 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 PFH30585.1 - 0.099 12.4 0.5 0.63 9.8 0.1 2.5 3 1 0 3 3 3 0 IstB-like ATP binding protein ABC_tran PF00005.27 PFH30585.1 - 0.56 10.7 0.0 0.56 10.7 0.0 2.9 2 1 0 2 2 1 0 ABC transporter Ribosomal_L11_N PF03946.14 PFH30588.1 - 9.2e-10 38.2 0.0 1.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain DDE_Tnp_IS240 PF13610.6 PFH30588.1 - 0.061 13.5 1.6 0.075 13.3 1.6 1.1 1 0 0 1 1 1 0 DDE domain GTP_EFTU PF00009.27 PFH30589.1 - 1.1e-59 201.2 0.8 1.9e-59 200.5 0.8 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PFH30589.1 - 7.5e-26 90.6 0.2 1.7e-25 89.5 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PFH30589.1 - 2.1e-13 50.4 3.0 4.3e-13 49.5 3.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 cobW PF02492.19 PFH30589.1 - 4.3e-05 23.2 0.2 0.0002 21.0 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 PFH30589.1 - 0.0001 22.3 0.1 0.00031 20.8 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PFH30589.1 - 0.0011 18.9 0.1 0.0026 17.7 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 PFH30589.1 - 0.0077 15.6 0.1 0.1 12.0 0.1 2.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 PFH30589.1 - 0.045 13.5 1.5 3.6 7.3 1.5 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S7 PF00177.21 PFH30590.1 - 5.3e-12 45.6 0.1 6.1e-12 45.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosom_S12_S23 PF00164.25 PFH30591.1 - 2.3e-31 107.8 4.1 2.6e-31 107.6 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DMP12 PF16779.5 PFH30591.1 - 0.17 11.8 0.0 1.6 8.7 0.0 2.0 1 1 0 2 2 2 0 DNA-mimic protein Ribosomal_S11 PF00411.19 PFH30592.1 - 6.6e-05 23.3 0.0 9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Oxidored_q4 PF00507.19 PFH30592.1 - 0.00049 20.2 0.3 0.00067 19.8 0.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Ribosomal_L36 PF00444.18 PFH30593.1 - 1.1e-05 25.5 12.8 1.2e-05 25.4 12.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 Ribosomal_S5 PF00333.20 PFH30594.1 - 6.2e-11 42.1 0.1 1e-10 41.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain PAS_9 PF13426.7 PFH30594.1 - 0.14 12.5 2.6 0.28 11.4 1.7 2.1 2 1 0 2 2 2 0 PAS domain Ribosomal_L14 PF00238.19 PFH30596.1 - 1.6e-20 73.4 0.0 1.8e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L16 PF00252.18 PFH30598.1 - 5.4e-06 26.5 0.0 6.5e-06 26.2 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_S3_C PF00189.20 PFH30599.1 - 5.4e-13 49.3 0.1 8.2e-13 48.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain Ribosomal_S19 PF00203.21 PFH30600.1 - 3.8e-07 29.9 0.1 4e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L2_C PF03947.18 PFH30601.1 - 7.4e-33 113.4 0.0 9.9e-33 113.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 PFH30601.1 - 6.6e-10 38.8 0.0 1.8e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L4 PF00573.22 PFH30602.1 - 2.9e-10 40.1 1.1 7.9e-10 38.7 1.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family S4 PF01479.25 PFH30603.1 - 1.2e-12 47.3 0.0 2.7e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 PFH30603.1 - 2.9e-07 31.3 2.8 5.4e-07 30.4 2.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain COX3 PF00510.18 PFH30604.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III COX3 PF00510.18 PFH30605.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III COX1 PF00115.20 PFH30606.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30606.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Cytochrom_B_C PF00032.17 PFH30607.1 - 8.3e-20 71.0 6.4 1e-19 70.8 6.4 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30608.1 - 1.2e-19 70.5 6.6 1.5e-19 70.2 6.6 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30609.1 - 8e-100 334.7 60.5 8e-100 334.7 60.5 1.3 1 1 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30609.1 - 0.17 11.6 3.3 0.92 9.3 3.3 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Cytochrom_B_C PF00032.17 PFH30610.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30611.1 - 9.5e-51 172.3 16.0 1.7e-50 171.5 16.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30611.1 - 3.4e-28 98.8 9.3 4.5e-28 98.4 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30611.1 - 4.8e-12 46.1 0.2 4.8e-12 46.1 0.2 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30612.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30612.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30612.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30613.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30615.1 - 8.3e-20 71.0 6.4 1e-19 70.8 6.4 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30616.1 - 2.1e-10 40.0 0.3 2.1e-10 40.0 0.3 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cytochrom_B_C PF00032.17 PFH30617.1 - 1e-19 70.7 6.4 1.3e-19 70.3 6.4 1.2 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD TIC20 PF16166.5 PFH30617.1 - 0.11 12.3 5.5 0.12 12.2 5.5 1.1 1 0 0 1 1 1 0 Chloroplast import apparatus Tic20-like Cytochrom_B_C PF00032.17 PFH30618.1 - 5.8e-13 49.0 0.2 1.1e-12 48.1 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30622.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30622.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30622.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30623.1 - 4.3e-13 49.5 0.2 6.9e-13 48.8 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30624.1 - 5.6e-58 195.9 21.0 9.6e-58 195.1 21.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30624.1 - 8.8e-28 97.4 9.8 8.8e-28 97.4 9.8 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30624.1 - 5.7e-12 45.8 0.2 5.7e-12 45.8 0.2 3.4 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30624.1 - 0.024 14.8 1.2 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family Cytochrome_B PF00033.19 PFH30625.1 - 9.5e-51 172.3 16.0 1.7e-50 171.5 16.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30625.1 - 3.4e-28 98.8 9.3 4.5e-28 98.4 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30625.1 - 4.8e-12 46.1 0.2 4.8e-12 46.1 0.2 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30627.1 - 3.4e-50 170.5 17.2 5.6e-50 169.8 17.2 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30627.1 - 3.2e-28 98.8 9.3 4.2e-28 98.4 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30627.1 - 4.7e-12 46.1 0.2 4.7e-12 46.1 0.2 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30628.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD DUF2407_C PF13373.6 PFH30629.1 - 0.17 12.1 1.0 2.3 8.4 0.0 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX3 PF00510.18 PFH30630.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30631.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30632.1 - 7.4e-50 169.4 16.1 7.4e-50 169.4 16.1 2.3 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30632.1 - 2.1e-27 96.2 9.8 2.1e-27 96.2 9.8 2.1 2 1 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30632.1 - 3.3e-26 91.6 23.5 3e-15 56.3 6.3 4.1 3 1 0 3 3 3 2 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30633.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III COX1 PF00115.20 PFH30635.1 - 9.2e-99 331.2 58.6 1.1e-98 330.9 58.6 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30635.1 - 0.14 11.9 3.3 0.84 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) COX1 PF00115.20 PFH30636.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30636.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Cytochrom_B_C PF00032.17 PFH30637.1 - 6.2e-13 48.9 0.2 6.2e-13 48.9 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30638.1 - 1.3e-12 47.9 0.2 1.3e-12 47.9 0.2 1.5 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30639.1 - 7.6e-13 48.6 0.2 7.6e-13 48.6 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30640.1 - 5.8e-10 38.6 3.3 6e-10 38.6 3.3 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cytochrom_B_C PF00032.17 PFH30641.1 - 8.3e-20 71.0 6.4 1e-19 70.8 6.4 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30642.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30643.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30644.1 - 6.4e-13 48.9 1.0 7.6e-13 48.6 0.2 1.5 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30645.1 - 3.1e-50 170.7 16.7 5.4e-50 169.8 16.7 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30645.1 - 3.6e-28 98.7 9.3 4.8e-28 98.3 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30645.1 - 5e-12 46.0 0.2 5e-12 46.0 0.2 3.1 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30646.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30647.1 - 6.2e-13 48.9 0.2 6.2e-13 48.9 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD DUF2407_C PF13373.6 PFH30648.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX3 PF00510.18 PFH30649.1 - 8.2e-09 35.7 4.6 9.3e-09 35.5 4.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Bac_export_2 PF01312.19 PFH30649.1 - 0.37 10.0 1.9 0.46 9.7 1.9 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF2407_C PF13373.6 PFH30650.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30651.1 - 6.9e-13 48.8 1.0 8.8e-13 48.4 0.2 1.6 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30652.1 - 4.4e-12 46.2 0.4 4.9e-12 46.1 0.4 1.0 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30653.1 - 7.6e-13 48.6 0.2 7.6e-13 48.6 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30654.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30654.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) COX1 PF00115.20 PFH30656.1 - 6.4e-06 25.3 0.3 6.4e-06 25.3 0.3 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cytochrome_B PF00033.19 PFH30657.1 - 5.6e-58 195.9 21.0 9.6e-58 195.1 21.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30657.1 - 8.8e-28 97.4 9.8 8.8e-28 97.4 9.8 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30657.1 - 5.7e-12 45.8 0.2 5.7e-12 45.8 0.2 3.4 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30657.1 - 0.024 14.8 1.2 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family Cytochrom_B_C PF00032.17 PFH30658.1 - 4.1e-13 49.5 0.2 4.1e-13 49.5 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30659.1 - 1.3e-51 175.1 15.3 2.2e-51 174.4 15.3 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30659.1 - 3.8e-28 98.6 9.3 5.1e-28 98.2 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30659.1 - 5.1e-12 46.0 0.2 5.1e-12 46.0 0.2 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B561 PF03188.16 PFH30659.1 - 6 7.0 18.2 7.6 6.7 1.1 3.7 2 2 1 3 3 3 0 Eukaryotic cytochrome b561 DUF2407_C PF13373.6 PFH30661.1 - 0.058 13.6 1.1 1.1 9.4 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX3 PF00510.18 PFH30662.1 - 1.4e-05 25.1 4.2 1.8e-05 24.8 4.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrome_B PF00033.19 PFH30663.1 - 3.4e-98 327.1 49.6 1.5e-49 168.4 16.1 2.9 2 1 1 3 3 3 2 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30663.1 - 1.1e-53 181.6 31.2 1.8e-27 96.4 8.6 2.6 3 0 0 3 3 3 2 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30663.1 - 1.2e-26 93.0 11.4 1.8e-16 60.3 5.8 5.1 4 2 1 5 5 5 2 Cytochrome b(C-terminal)/b6/petD SH3_16 PF18348.1 PFH30663.1 - 0.013 15.3 0.2 7.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain DUF5436 PF17504.2 PFH30663.1 - 0.03 14.6 0.2 27 5.2 0.0 3.4 2 0 0 2 2 2 0 Family of unknown function (DUF5436) Questin_oxidase PF14027.6 PFH30663.1 - 1.6 8.2 10.6 4.3 6.8 1.9 2.1 2 0 0 2 2 2 0 Questin oxidase-like DUF5083 PF16890.5 PFH30663.1 - 4.1 7.1 15.2 1.9 8.2 1.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5083) Cytochrom_B_C PF00032.17 PFH30664.1 - 8.3e-20 71.0 6.4 1e-19 70.8 6.4 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD DUF2407_C PF13373.6 PFH30665.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30666.1 - 1.2e-19 70.5 6.4 1.8e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30667.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III DUF2407_C PF13373.6 PFH30668.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrome_B PF00033.19 PFH30670.1 - 2.6e-50 170.9 16.2 4.5e-50 170.1 16.2 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30670.1 - 6.4e-28 97.9 9.8 8.7e-28 97.4 9.8 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30670.1 - 5.6e-12 45.9 0.2 5.6e-12 45.9 0.2 3.1 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30671.1 - 2.3e-13 50.3 0.4 2.4e-13 50.2 0.4 1.0 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30672.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30672.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30672.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD DUF2407_C PF13373.6 PFH30673.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain DUF2407_C PF13373.6 PFH30674.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX3 PF00510.18 PFH30675.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30676.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30677.1 - 4.1e-13 49.5 0.2 4.1e-13 49.5 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30678.1 - 0.0016 17.4 7.2 0.002 17.1 7.2 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX3 PF00510.18 PFH30678.1 - 0.0036 17.2 8.9 0.0062 16.4 8.8 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III DUF981 PF06168.11 PFH30678.1 - 0.043 13.7 8.8 0.075 13.0 8.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF373 PF04123.13 PFH30678.1 - 0.28 10.6 4.8 0.31 10.4 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2407_C PF13373.6 PFH30678.1 - 0.4 10.9 1.3 4.4 7.5 0.0 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30679.1 - 4.1e-13 49.5 0.2 4.1e-13 49.5 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30681.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30681.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Ion_trans PF00520.31 PFH30682.1 - 3.9e-17 62.3 28.1 9.1e-14 51.3 13.0 4.6 3 2 0 4 4 4 3 Ion transport protein Cytochrome_B PF00033.19 PFH30683.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30683.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30683.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30684.1 - 4.9e-13 49.3 0.2 4.9e-13 49.3 0.2 1.5 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD DUF2407_C PF13373.6 PFH30685.1 - 0.016 15.4 0.9 1.1 9.4 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrome_B PF00033.19 PFH30686.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30686.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30686.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30687.1 - 4.1e-13 49.5 0.2 4.1e-13 49.5 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30688.1 - 5.6e-58 195.9 21.0 9.6e-58 195.1 21.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30688.1 - 8.8e-28 97.4 9.8 8.8e-28 97.4 9.8 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30688.1 - 5.7e-12 45.8 0.2 5.7e-12 45.8 0.2 3.4 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30688.1 - 0.024 14.8 1.2 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family Cytochrome_B PF00033.19 PFH30689.1 - 1.5e-50 171.7 16.1 2.3e-50 171.1 16.1 1.2 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30689.1 - 3.9e-28 98.6 9.5 5e-28 98.2 9.5 1.1 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30689.1 - 1.1e-06 28.9 1.0 1.1e-06 28.9 1.0 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30691.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III DUF2407_C PF13373.6 PFH30692.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX3 PF00510.18 PFH30693.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30694.1 - 1.4e-12 47.8 0.2 1.4e-12 47.8 0.2 2.1 3 0 0 3 3 3 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30694.1 - 4.9e-07 29.8 4.5 6.5e-07 29.5 4.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Kinase-like PF14531.6 PFH30695.1 - 6.2e-17 61.8 0.0 8.9e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH30695.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain RPAP1_N PF08621.10 PFH30696.1 - 4.3e-07 29.6 4.9 4.3e-07 29.6 4.9 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal RPAP1_C PF08620.10 PFH30697.1 - 1.5e-21 76.2 0.0 4.5e-21 74.7 0.0 1.8 2 1 0 2 2 2 1 RPAP1-like, C-terminal RIC1 PF07064.13 PFH30698.1 - 8e-14 51.7 1.7 3.8e-13 49.4 0.1 2.2 2 0 0 2 2 2 1 RIC1 DUF2474 PF10617.9 PFH30698.1 - 0.13 12.1 1.5 0.36 10.7 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) Kinase-like PF14531.6 PFH30699.1 - 3.4e-27 95.5 0.0 1.1e-21 77.4 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Pkinase PF00069.25 PFH30699.1 - 5.1e-09 35.9 0.0 9e-09 35.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH30699.1 - 7.5e-06 25.4 0.0 1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PFH30699.1 - 0.0028 17.3 0.0 0.0059 16.2 0.0 1.5 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 PFH30699.1 - 0.0038 17.2 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ion_trans PF00520.31 PFH30700.1 - 2.8e-10 39.8 16.0 5.1e-08 32.4 16.7 2.2 2 0 0 2 2 2 2 Ion transport protein DUF502 PF04367.13 PFH30700.1 - 0.11 12.4 0.4 0.24 11.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF502) PKD_channel PF08016.12 PFH30700.1 - 6.5 5.3 12.2 15 4.2 6.5 2.4 1 1 1 2 2 2 0 Polycystin cation channel Cytochrom_B_C PF00032.17 PFH30701.1 - 8.5e-20 71.0 6.4 1.1e-19 70.7 6.4 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30702.1 - 8.4e-17 61.4 5.9 1e-16 61.1 5.9 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30703.1 - 4.1e-13 49.5 0.2 4.1e-13 49.5 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30704.1 - 2.7e-35 121.9 9.1 2.9e-35 121.8 9.1 1.0 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30704.1 - 1.2e-09 38.4 2.4 1.2e-09 38.4 2.4 1.8 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB DUF1516 PF07457.11 PFH30704.1 - 0.22 11.7 7.5 4.4 7.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) Questin_oxidase PF14027.6 PFH30704.1 - 0.31 10.5 1.8 0.37 10.3 1.8 1.1 1 0 0 1 1 1 0 Questin oxidase-like Cytochrom_B561 PF03188.16 PFH30704.1 - 0.48 10.6 12.1 5.9 7.0 4.8 2.4 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 Ni_hydr_CYTB PF01292.20 PFH30704.1 - 0.62 9.6 13.8 0.051 13.2 4.3 2.1 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF4405 PF14358.6 PFH30704.1 - 0.99 10.0 12.7 0.27 11.8 7.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) DUF4079 PF13301.6 PFH30704.1 - 7.6 6.7 10.2 10 6.2 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) COX3 PF00510.18 PFH30705.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30706.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30707.1 - 3.7e-19 68.9 6.4 3.7e-19 68.9 6.4 1.8 3 0 0 3 3 3 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30707.1 - 5.1e-06 26.5 7.4 5.1e-06 26.5 7.4 2.0 2 1 0 2 2 2 1 Cytochrome c oxidase subunit III SK_channel PF03530.14 PFH30707.1 - 1.3 9.0 6.9 0.099 12.6 0.7 2.1 1 1 0 2 2 2 0 Calcium-activated SK potassium channel COX3 PF00510.18 PFH30708.1 - 1.8e-07 31.3 5.6 1.9e-07 31.2 5.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III TMEMspv1-c74-12 PF11044.8 PFH30708.1 - 3.4 7.7 6.4 9.4 6.3 3.3 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Cytochrom_B_C PF00032.17 PFH30709.1 - 6.2e-13 48.9 0.2 6.2e-13 48.9 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD DUF2407_C PF13373.6 PFH30710.1 - 0.13 12.4 0.6 2.1 8.5 0.0 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain DUF981 PF06168.11 PFH30710.1 - 0.34 10.8 10.8 0.21 11.5 9.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF981) ECF_trnsprt PF12822.7 PFH30710.1 - 9.2 6.3 15.2 28 4.7 1.7 2.7 1 1 1 2 2 2 0 ECF transporter, substrate-specific component COX1 PF00115.20 PFH30711.1 - 1.1e-15 57.5 3.1 1.2e-15 57.3 3.1 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cytochrom_B_C PF00032.17 PFH30712.1 - 4.3e-13 49.4 0.2 6.9e-13 48.8 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD DUF2407_C PF13373.6 PFH30713.1 - 0.076 13.2 1.0 1.1 9.4 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX3 PF00510.18 PFH30714.1 - 3e-07 30.6 5.6 3.4e-07 30.4 5.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III TMEMspv1-c74-12 PF11044.8 PFH30714.1 - 6.1 6.9 6.4 13 5.8 3.3 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Cytochrome_B PF00033.19 PFH30715.1 - 5.5e-58 195.9 21.0 8.2e-58 195.3 21.0 1.2 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30715.1 - 5.7e-28 98.0 9.2 5.7e-28 98.0 9.2 1.5 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB TrbC PF04956.13 PFH30715.1 - 0.17 12.1 4.6 2.3 8.5 1.2 2.9 3 1 0 3 3 3 0 TrbC/VIRB2 family Cytochrom_B_C PF00032.17 PFH30716.1 - 6.2e-13 48.9 0.2 6.2e-13 48.9 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30717.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30717.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30717.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30718.1 - 1.4e-19 70.3 6.4 2.4e-19 69.5 6.4 1.4 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30719.1 - 0.0052 15.7 8.0 0.0067 15.3 8.0 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF981 PF06168.11 PFH30719.1 - 0.024 14.6 8.5 0.039 13.9 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2407_C PF13373.6 PFH30719.1 - 0.24 11.6 1.2 3.1 8.0 0.0 2.2 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30720.1 - 3.6e-09 36.8 0.2 3.6e-09 36.8 0.2 2.1 3 0 0 3 3 3 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30720.1 - 6.2e-07 29.5 5.0 9.2e-07 28.9 5.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30721.1 - 2.1e-13 50.4 1.7 6.9e-13 48.8 0.2 2.0 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30722.1 - 3.4e-50 170.5 17.2 5.6e-50 169.8 17.2 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30722.1 - 3.2e-28 98.8 9.3 4.2e-28 98.4 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30722.1 - 4.7e-12 46.1 0.2 4.7e-12 46.1 0.2 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30724.1 - 1.8e-12 47.4 0.9 1.9e-12 47.4 0.1 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30725.1 - 0.13 12.6 0.8 0.13 12.6 0.8 2.7 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF2407_C PF13373.6 PFH30725.1 - 0.33 11.1 0.7 4.1 7.6 0.0 2.2 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30726.1 - 1.3e-12 47.9 0.2 1.3e-12 47.9 0.2 1.5 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD DUF2407_C PF13373.6 PFH30727.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Kinase-like PF14531.6 PFH30728.1 - 5.8e-47 160.4 0.0 7.4e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH30728.1 - 8.8e-20 71.2 0.0 1e-14 54.6 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH30728.1 - 0.0018 17.6 0.0 0.033 13.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Rv2175c_C PF18367.1 PFH30728.1 - 0.0064 16.6 0.1 0.022 14.8 0.1 1.9 1 0 0 1 1 1 1 Rv2175c C-terminal domain of unknown function PIP49_C PF12260.8 PFH30728.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pox_ser-thr_kin PF05445.11 PFH30728.1 - 0.057 12.4 0.0 0.084 11.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ion_trans PF00520.31 PFH30729.1 - 3e-22 79.0 23.9 4.6e-15 55.5 20.7 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 PFH30729.1 - 0.00012 20.9 16.9 0.00018 20.4 11.6 2.2 1 1 1 2 2 2 2 Polycystin cation channel DUF502 PF04367.13 PFH30729.1 - 0.075 12.9 0.3 0.21 11.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF502) Cytochrome_B PF00033.19 PFH30730.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30730.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30730.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30731.1 - 3.4e-19 69.0 6.4 3.4e-19 69.0 6.4 1.8 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30731.1 - 1.7e-06 28.1 4.4 1.7e-06 28.1 4.4 2.0 2 1 0 2 2 2 1 Cytochrome c oxidase subunit III DUF2407_C PF13373.6 PFH30733.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrome_B PF00033.19 PFH30734.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30734.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30734.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30735.1 - 8.5e-51 172.5 15.4 1.6e-50 171.6 15.4 1.4 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30735.1 - 6.9e-28 97.8 9.8 1e-27 97.2 9.8 1.3 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30735.1 - 4.2e-14 52.7 0.9 4.2e-14 52.7 0.9 3.0 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30737.1 - 5.6e-58 195.9 21.0 9.6e-58 195.1 21.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30737.1 - 8.8e-28 97.4 9.8 8.8e-28 97.4 9.8 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30737.1 - 5.7e-12 45.8 0.2 5.7e-12 45.8 0.2 3.4 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30737.1 - 0.024 14.8 1.2 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family Cytochrome_B PF00033.19 PFH30738.1 - 9.5e-51 172.3 16.0 1.7e-50 171.5 16.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30738.1 - 3.4e-28 98.8 9.3 4.5e-28 98.4 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30738.1 - 4.8e-12 46.1 0.2 4.8e-12 46.1 0.2 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30739.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30739.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30739.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD DUF2938 PF11158.8 PFH30741.1 - 0.071 12.6 0.2 0.082 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) MtrB PF05440.12 PFH30741.1 - 1.1 9.7 3.4 6 7.4 0.1 2.1 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF2407_C PF13373.6 PFH30742.1 - 0.081 13.1 1.0 1.2 9.3 0.1 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain DUF2407_C PF13373.6 PFH30743.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrome_B PF00033.19 PFH30744.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30744.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30744.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30745.1 - 1.6e-19 70.1 6.4 2.1e-19 69.7 6.4 1.2 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30746.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrome_B PF00033.19 PFH30748.1 - 1.9e-57 194.1 21.0 1.9e-57 194.1 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30748.1 - 1.7e-27 96.5 9.8 1.7e-27 96.5 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30748.1 - 1.4e-18 67.0 6.4 1.4e-18 67.0 6.4 3.3 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30749.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30750.1 - 6.2e-13 48.9 0.2 6.2e-13 48.9 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30751.1 - 3.9e-46 157.8 21.9 4.8e-46 157.5 21.9 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DHHC PF01529.20 PFH30751.1 - 2.3 8.3 14.9 0.14 12.2 1.8 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF2407_C PF13373.6 PFH30752.1 - 0.09 13.0 1.0 1.6 8.9 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30754.1 - 8.3e-20 71.0 6.4 1e-19 70.8 6.4 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30755.1 - 1.2e-19 70.5 6.4 2e-19 69.8 6.4 1.4 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30756.1 - 3.3e-19 69.1 6.4 3.3e-19 69.1 6.4 1.7 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30756.1 - 1.5e-06 28.3 4.3 1.5e-06 28.3 4.3 2.0 2 1 0 2 2 2 1 Cytochrome c oxidase subunit III COX1 PF00115.20 PFH30757.1 - 4.8e-100 335.4 58.9 4.8e-100 335.4 58.9 1.3 1 1 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30757.1 - 0.16 11.7 3.3 0.92 9.3 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Cytochrom_B_C PF00032.17 PFH30758.1 - 1.2e-19 70.5 6.4 2.2e-19 69.6 6.4 1.4 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30759.1 - 1.5e-07 31.5 5.4 1.7e-07 31.4 5.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III TMEMspv1-c74-12 PF11044.8 PFH30759.1 - 3.4 7.7 6.4 9.6 6.3 3.3 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Cytochrome_B PF00033.19 PFH30760.1 - 7.3e-51 172.7 18.7 1.2e-50 172.0 18.7 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30760.1 - 3.5e-28 98.7 9.3 4.8e-28 98.3 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30760.1 - 4.9e-12 46.0 0.2 4.9e-12 46.0 0.2 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD RIC1 PF07064.13 PFH30761.1 - 8.5e-11 41.7 0.0 1.4e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 RIC1 DUF2474 PF10617.9 PFH30761.1 - 0.077 12.9 1.5 0.21 11.5 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) Herpes_capsid PF06112.11 PFH30762.1 - 1.2 9.1 9.2 2.8 8.0 0.0 3.6 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein RPAP1_N PF08621.10 PFH30763.1 - 4.3e-07 29.6 4.9 4.3e-07 29.6 4.9 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal Kinase-like PF14531.6 PFH30764.1 - 1.1e-38 133.2 0.0 1.5e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH30764.1 - 2.9e-08 33.4 0.0 0.00027 20.4 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH30764.1 - 0.00011 21.6 0.0 0.00059 19.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PFH30764.1 - 0.0026 17.4 0.0 0.0042 16.7 0.0 1.4 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 PFH30764.1 - 0.0039 17.2 0.0 0.0068 16.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Cytochrom_B_C PF00032.17 PFH30766.1 - 2.1e-13 50.4 1.7 6.9e-13 48.8 0.2 2.0 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30767.1 - 3.4e-19 69.0 6.4 3.4e-19 69.0 6.4 1.8 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30767.1 - 1.7e-06 28.1 4.4 1.7e-06 28.1 4.4 2.0 2 1 0 2 2 2 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30768.1 - 2.3e-13 50.3 0.4 2.4e-13 50.2 0.4 1.0 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30769.1 - 2.5e-50 170.9 14.5 4.3e-50 170.2 14.5 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30769.1 - 3.8e-28 98.6 9.3 5e-28 98.2 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30769.1 - 5.1e-12 46.0 0.2 5.1e-12 46.0 0.2 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Questin_oxidase PF14027.6 PFH30769.1 - 0.54 9.7 1.7 0.76 9.3 1.7 1.1 1 0 0 1 1 1 0 Questin oxidase-like COX3 PF00510.18 PFH30770.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrome_B PF00033.19 PFH30771.1 - 9.5e-51 172.3 16.0 1.7e-50 171.5 16.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30771.1 - 3.4e-28 98.8 9.3 4.5e-28 98.4 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30771.1 - 4.8e-12 46.1 0.2 4.8e-12 46.1 0.2 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30772.1 - 5.6e-58 195.9 21.0 9.6e-58 195.1 21.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30772.1 - 8.8e-28 97.4 9.8 8.8e-28 97.4 9.8 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30772.1 - 5.7e-12 45.8 0.2 5.7e-12 45.8 0.2 3.4 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30772.1 - 0.024 14.8 1.2 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family COX3 PF00510.18 PFH30773.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30774.1 - 6.2e-13 48.9 0.2 6.2e-13 48.9 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30775.1 - 8e-20 71.1 6.4 9.7e-20 70.8 6.4 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30776.1 - 1.4e-57 194.6 20.6 1.4e-57 194.6 20.6 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30776.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30776.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD UPF0715 PF17094.5 PFH30777.1 - 0.028 15.0 4.3 18 5.9 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0715) DUF287 PF03384.14 PFH30777.1 - 0.04 14.3 2.0 11 6.5 0.1 2.8 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 DUF3197 PF11432.8 PFH30777.1 - 0.054 13.4 2.4 13 5.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3197) DUF2974 PF11187.8 PFH30777.1 - 0.056 13.0 0.1 8.2 5.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) FixS PF03597.15 PFH30777.1 - 0.075 12.8 9.5 1.4 8.7 0.0 3.6 4 0 0 4 4 4 0 Cytochrome oxidase maturation protein cbb3-type Aft1_HRR PF11787.8 PFH30777.1 - 0.24 12.6 0.8 2.6e+02 2.9 0.0 3.5 3 0 0 3 3 3 0 Aft1 HRR domain CdiI_3 PF18616.1 PFH30777.1 - 1.2 9.1 5.9 73 3.3 0.1 3.4 3 0 0 3 3 3 0 CDI immunity proteins DUF2974 PF11187.8 PFH30779.1 - 0.00012 21.7 0.2 4.6 6.7 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF2974) DUF3197 PF11432.8 PFH30779.1 - 0.0047 16.8 3.8 17 5.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3197) UPF0715 PF17094.5 PFH30779.1 - 0.0093 16.5 10.5 27 5.4 0.2 4.4 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0715) DUF287 PF03384.14 PFH30779.1 - 0.016 15.6 7.9 15 6.0 0.2 3.8 3 0 0 3 3 3 0 Drosophila protein of unknown function, DUF287 DNA_pol3_beta_2 PF02767.16 PFH30779.1 - 0.035 14.3 0.2 1.2e+02 3.0 0.0 4.1 4 0 0 4 4 4 0 DNA polymerase III beta subunit, central domain Aft1_HRR PF11787.8 PFH30779.1 - 0.069 14.3 2.3 3.5e+02 2.5 0.0 4.5 4 0 0 4 4 4 0 Aft1 HRR domain ComJ PF11033.8 PFH30779.1 - 0.1 12.3 0.1 1.1e+02 2.6 0.0 3.3 3 0 0 3 3 3 0 Competence protein J (ComJ) RNA_binding PF01877.17 PFH30779.1 - 0.13 12.5 0.0 1.4e+02 2.8 0.0 3.2 3 0 0 3 3 3 0 RNA binding PIF2 PF04631.12 PFH30779.1 - 0.16 10.8 0.0 74 2.0 0.0 3.1 3 0 0 3 3 3 0 Per os infectivity factor 2 FixS PF03597.15 PFH30779.1 - 3.5 7.4 24.5 1.8 8.3 0.0 4.8 6 0 0 6 6 6 0 Cytochrome oxidase maturation protein cbb3-type CSTF2_hinge PF14327.6 PFH30779.1 - 4.5 7.8 10.8 63 4.1 0.4 3.8 3 0 0 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 DUF3197 PF11432.8 PFH30780.1 - 0.00057 19.8 7.7 18 5.3 0.1 4.3 4 0 0 4 4 4 4 Protein of unknown function (DUF3197) DUF287 PF03384.14 PFH30780.1 - 0.019 15.3 7.9 16 6.0 0.2 3.7 3 0 0 3 3 3 0 Drosophila protein of unknown function, DUF287 Lipoprotein_16 PF03923.13 PFH30780.1 - 0.049 13.3 0.0 73 3.0 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized lipoprotein UPF0715 PF17094.5 PFH30780.1 - 0.07 13.7 7.5 27 5.3 0.2 3.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0715) ComJ PF11033.8 PFH30780.1 - 0.12 12.1 0.1 1.1e+02 2.5 0.0 3.2 3 0 0 3 3 3 0 Competence protein J (ComJ) DNA_pol3_beta_2 PF02767.16 PFH30780.1 - 0.12 12.6 0.0 1.6e+02 2.5 0.0 3.4 3 0 0 3 3 3 0 DNA polymerase III beta subunit, central domain PIF2 PF04631.12 PFH30780.1 - 0.19 10.5 0.0 77 2.0 0.0 3.1 3 0 0 3 3 3 0 Per os infectivity factor 2 Lipoprotein_16 PF03923.13 PFH30781.1 - 0.035 13.8 0.0 66 3.1 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized lipoprotein DUF287 PF03384.14 PFH30781.1 - 0.036 14.5 9.6 14 6.1 0.2 4.0 4 0 0 4 4 4 0 Drosophila protein of unknown function, DUF287 ComJ PF11033.8 PFH30781.1 - 0.088 12.5 0.1 98 2.7 0.0 3.3 3 0 0 3 3 3 0 Competence protein J (ComJ) DUF3197 PF11432.8 PFH30781.1 - 0.096 12.6 2.4 16 5.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3197) UPF0715 PF17094.5 PFH30781.1 - 0.13 12.8 5.6 24 5.5 0.2 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0715) PIF2 PF04631.12 PFH30781.1 - 0.15 10.8 0.0 69 2.1 0.0 3.1 3 0 0 3 3 3 0 Per os infectivity factor 2 CdiI_3 PF18616.1 PFH30781.1 - 1.8 8.5 5.5 91 3.0 0.1 3.3 3 0 0 3 3 3 0 CDI immunity proteins RPAP1_N PF08621.10 PFH30782.1 - 4.2e-07 29.6 4.9 9.6e-07 28.5 4.9 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal RPAP1_C PF08620.10 PFH30782.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 RPAP1-like, C-terminal Kinase-like PF14531.6 PFH30783.1 - 1.3e-36 126.4 0.0 1.6e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH30783.1 - 5.2e-08 32.6 0.0 0.00048 19.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH30783.1 - 0.00075 18.9 0.0 0.0042 16.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PFH30783.1 - 0.0031 17.1 0.0 0.0046 16.6 0.0 1.4 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 PFH30783.1 - 0.006 16.5 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2474 PF10617.9 PFH30784.1 - 0.15 11.9 1.5 0.4 10.6 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) Cytochrom_B_C PF00032.17 PFH30785.1 - 9.3e-19 67.6 6.4 9.3e-19 67.6 6.4 2.5 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30786.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30787.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III DUF2407_C PF13373.6 PFH30788.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrome_B PF00033.19 PFH30789.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30789.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30789.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30790.1 - 6.9e-49 166.2 22.7 6.9e-49 166.2 22.7 2.0 2 1 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30790.1 - 1.1e-27 97.1 8.8 1.1e-27 97.1 8.8 2.0 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30790.1 - 9.5e-12 45.1 0.2 9.5e-12 45.1 0.2 4.1 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30791.1 - 0.0052 15.7 8.0 0.0067 15.3 8.0 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF981 PF06168.11 PFH30791.1 - 0.024 14.6 8.5 0.039 13.9 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2407_C PF13373.6 PFH30791.1 - 0.24 11.6 1.2 3.1 8.0 0.0 2.2 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30792.1 - 4.4e-13 49.4 0.5 6.1e-13 49.0 0.5 1.2 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30793.1 - 1.9e-39 135.7 26.4 2.3e-39 135.5 26.4 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DPM3 PF08285.11 PFH30793.1 - 1.6 9.0 7.4 0.72 10.1 2.1 2.5 1 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3789 PF12664.7 PFH30793.1 - 2.3 8.0 8.5 0.28 10.9 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) Cytochrome_B PF00033.19 PFH30794.1 - 5.1e-50 169.9 15.6 8.1e-50 169.3 15.6 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30794.1 - 3.4e-28 98.8 9.3 4.4e-28 98.4 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30794.1 - 4.8e-12 46.1 0.2 4.8e-12 46.1 0.2 3.1 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30795.1 - 3.4e-19 69.0 6.4 3.4e-19 69.0 6.4 1.8 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30795.1 - 1.7e-06 28.1 4.4 1.7e-06 28.1 4.4 2.0 2 1 0 2 2 2 1 Cytochrome c oxidase subunit III Cytochrome_B PF00033.19 PFH30796.1 - 2.2e-57 194.0 21.3 2.2e-57 194.0 21.3 1.7 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30796.1 - 1e-27 97.2 9.1 1e-27 97.2 9.1 1.7 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30796.1 - 3e-11 43.5 0.5 3e-11 43.5 0.5 3.7 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30796.1 - 0.081 13.2 1.9 2.3 8.5 0.3 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family Cytochrom_B_C PF00032.17 PFH30797.1 - 1.3e-19 70.4 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30798.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III DUF2407_C PF13373.6 PFH30799.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX1 PF00115.20 PFH30800.1 - 1.1e-46 159.7 19.8 1.2e-46 159.4 19.8 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DHHC PF01529.20 PFH30800.1 - 2.4 8.3 15.0 0.17 12.0 2.0 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase Cytochrom_B_C PF00032.17 PFH30801.1 - 3e-13 49.9 0.2 3.7e-13 49.7 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30802.1 - 1.1e-12 48.1 0.6 1.1e-12 48.1 0.6 1.5 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD DUF981 PF06168.11 PFH30803.1 - 0.041 13.8 6.8 0.057 13.3 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2407_C PF13373.6 PFH30803.1 - 0.11 12.7 0.7 1.9 8.7 0.0 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain DUF2407_C PF13373.6 PFH30805.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30806.1 - 1e-19 70.7 6.4 1.3e-19 70.3 6.4 1.2 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30808.1 - 1.9e-12 47.4 1.2 3e-12 46.7 1.2 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30809.1 - 8.3e-20 71.0 6.4 1e-19 70.8 6.4 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30810.1 - 0.0052 15.7 8.0 0.0067 15.3 8.0 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF981 PF06168.11 PFH30810.1 - 0.024 14.6 8.5 0.039 13.9 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2407_C PF13373.6 PFH30810.1 - 0.24 11.6 1.2 3.1 8.0 0.0 2.2 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30811.1 - 8.3e-20 71.0 6.4 1e-19 70.8 6.4 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30812.1 - 3.6e-58 196.5 21.0 4.6e-58 196.2 21.0 1.1 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30812.1 - 9.9e-28 97.2 7.1 9.9e-28 97.2 7.1 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB TrbC PF04956.13 PFH30812.1 - 0.14 12.4 4.5 2.1 8.6 1.5 2.6 2 1 0 2 2 2 0 TrbC/VIRB2 family COX3 PF00510.18 PFH30813.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III COX1 PF00115.20 PFH30814.1 - 0.0052 15.7 8.0 0.0067 15.3 8.0 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF981 PF06168.11 PFH30814.1 - 0.024 14.6 8.5 0.039 13.9 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2407_C PF13373.6 PFH30814.1 - 0.24 11.6 1.2 3.1 8.0 0.0 2.2 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30815.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30816.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD DUF386 PF04074.12 PFH30818.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 YhcH/YjgK/YiaL Cytochrom_B_C PF00032.17 PFH30820.1 - 1e-19 70.7 6.4 1.7e-19 70.0 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD TIC20 PF16166.5 PFH30820.1 - 0.52 10.1 7.5 0.66 9.7 7.5 1.2 1 0 0 1 1 1 0 Chloroplast import apparatus Tic20-like Cytochrome_B PF00033.19 PFH30821.1 - 5.6e-58 195.9 21.0 9.6e-58 195.1 21.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30821.1 - 8.8e-28 97.4 9.8 8.8e-28 97.4 9.8 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30821.1 - 5.7e-12 45.8 0.2 5.7e-12 45.8 0.2 3.4 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30821.1 - 0.024 14.8 1.2 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family COX3 PF00510.18 PFH30822.1 - 0.0073 16.2 6.8 0.011 15.6 6.8 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III DUF2407_C PF13373.6 PFH30822.1 - 0.33 11.1 1.0 3.2 7.9 0.0 2.2 1 1 1 2 2 2 0 DUF2407 C-terminal domain DUF981 PF06168.11 PFH30822.1 - 0.35 10.8 11.5 0.65 9.9 11.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF981) Cytochrome_B PF00033.19 PFH30823.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30823.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30823.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30824.1 - 2.7e-07 30.7 5.6 3e-07 30.5 5.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III TMEMspv1-c74-12 PF11044.8 PFH30824.1 - 5.3 7.1 6.4 12 5.9 3.3 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Cytochrom_B_C PF00032.17 PFH30825.1 - 0.097 13.0 0.4 0.097 13.0 0.4 2.5 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF2407_C PF13373.6 PFH30825.1 - 0.16 12.2 0.2 2.4 8.4 0.0 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrome_B PF00033.19 PFH30826.1 - 5.6e-58 195.9 21.0 9.6e-58 195.1 21.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30826.1 - 8.8e-28 97.4 9.8 8.8e-28 97.4 9.8 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30826.1 - 5.7e-12 45.8 0.2 5.7e-12 45.8 0.2 3.4 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30826.1 - 0.024 14.8 1.2 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family Cytochrome_B PF00033.19 PFH30827.1 - 5.6e-58 195.9 21.0 9.6e-58 195.1 21.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30827.1 - 8.8e-28 97.4 9.8 8.8e-28 97.4 9.8 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30827.1 - 5.7e-12 45.8 0.2 5.7e-12 45.8 0.2 3.4 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30827.1 - 0.024 14.8 1.2 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family DUF2407_C PF13373.6 PFH30828.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30830.1 - 4.2e-12 46.3 0.2 4.2e-12 46.3 0.2 2.5 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD DUF2407_C PF13373.6 PFH30830.1 - 0.48 10.6 1.0 4.5 7.5 0.0 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX1 PF00115.20 PFH30831.1 - 2.6e-86 290.2 49.2 3.1e-86 289.9 49.2 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30831.1 - 0.12 12.1 3.3 0.67 9.7 3.3 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) DUF2407_C PF13373.6 PFH30833.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrome_B PF00033.19 PFH30834.1 - 9.5e-51 172.3 16.0 1.7e-50 171.5 16.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30834.1 - 3.4e-28 98.8 9.3 4.5e-28 98.4 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30834.1 - 4.8e-12 46.1 0.2 4.8e-12 46.1 0.2 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30835.1 - 2e-07 31.2 5.6 2.1e-07 31.0 5.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III TMEMspv1-c74-12 PF11044.8 PFH30835.1 - 3.8 7.6 6.4 10 6.2 3.3 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Cytochrom_B_C PF00032.17 PFH30836.1 - 1.5e-19 70.2 6.4 1.9e-19 69.9 6.4 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30837.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30838.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30839.1 - 1e-19 70.7 6.4 1.3e-19 70.3 6.4 1.2 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD TIC20 PF16166.5 PFH30839.1 - 0.11 12.3 5.5 0.12 12.2 5.5 1.1 1 0 0 1 1 1 0 Chloroplast import apparatus Tic20-like Cytochrome_B PF00033.19 PFH30840.1 - 1.8e-57 194.3 21.3 1.8e-57 194.3 21.3 1.6 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30840.1 - 1e-27 97.2 9.2 1e-27 97.2 9.2 1.7 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB TrbC PF04956.13 PFH30840.1 - 0.063 13.5 1.9 2 8.7 0.3 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family Cytochrom_B_C PF00032.17 PFH30841.1 - 1.4e-19 70.3 6.4 2.4e-19 69.5 6.4 1.4 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30842.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30842.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30842.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30843.1 - 1.7e-47 162.3 43.0 1.9e-45 155.5 25.4 2.0 1 1 1 2 2 2 2 Cytochrome C and Quinol oxidase polypeptide I COX1 PF00115.20 PFH30844.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30844.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) DUF981 PF06168.11 PFH30845.1 - 0.077 12.9 8.4 0.14 12.1 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2407_C PF13373.6 PFH30845.1 - 0.21 11.8 0.6 2.9 8.0 0.0 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30846.1 - 4.1e-13 49.5 0.2 4.1e-13 49.5 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30847.1 - 6.2e-13 48.9 0.2 6.2e-13 48.9 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30848.1 - 4.6e-13 49.3 0.4 5.3e-13 49.1 0.4 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30849.1 - 1.4e-19 70.3 6.4 2.4e-19 69.5 6.4 1.4 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30850.1 - 4.6e-19 68.6 6.4 4.6e-19 68.6 6.4 2.2 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30850.1 - 6.5e-08 32.7 3.8 6.5e-08 32.7 3.8 1.9 2 0 0 2 2 2 1 Cytochrome c oxidase subunit III Bac_export_2 PF01312.19 PFH30850.1 - 1.9 7.6 6.4 0.27 10.4 0.4 2.0 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family DUF2407_C PF13373.6 PFH30851.1 - 0.07 13.3 1.1 1.1 9.4 0.0 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX1 PF00115.20 PFH30852.1 - 0.0052 15.7 8.0 0.0067 15.3 8.0 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF981 PF06168.11 PFH30852.1 - 0.024 14.6 8.5 0.039 13.9 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2407_C PF13373.6 PFH30852.1 - 0.24 11.6 1.2 3.1 8.0 0.0 2.2 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30853.1 - 1e-19 70.7 6.4 1.6e-19 70.1 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30854.1 - 0.0052 15.7 8.0 0.0067 15.3 8.0 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF981 PF06168.11 PFH30854.1 - 0.024 14.6 8.5 0.039 13.9 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2407_C PF13373.6 PFH30854.1 - 0.24 11.6 1.2 3.1 8.0 0.0 2.2 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX1 PF00115.20 PFH30855.1 - 3e-70 237.3 33.0 3.3e-70 237.1 33.0 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DHHC PF01529.20 PFH30855.1 - 8.7 6.5 12.3 0.76 9.9 5.9 2.4 2 1 0 2 2 2 0 DHHC palmitoyltransferase Cytochrom_B_C PF00032.17 PFH30856.1 - 1.3e-19 70.4 6.4 1.9e-19 69.8 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30857.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrome_B PF00033.19 PFH30858.1 - 3.7e-37 128.0 16.3 6.5e-37 127.2 16.3 1.4 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30858.1 - 1.7e-28 99.7 9.0 2.1e-28 99.4 9.0 1.1 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30858.1 - 3.7e-12 46.4 0.2 3.7e-12 46.4 0.2 3.1 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B561 PF03188.16 PFH30858.1 - 0.57 10.3 11.5 4.4 7.4 1.1 2.9 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 DUF5083 PF16890.5 PFH30858.1 - 1.3 8.8 4.8 0.39 10.4 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) Cytochrome_B PF00033.19 PFH30859.1 - 3.1e-17 63.0 1.0 3.5e-17 62.9 1.0 1.0 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrome_B PF00033.19 PFH30860.1 - 3.7e-37 128.0 16.3 6.5e-37 127.2 16.3 1.4 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30860.1 - 1.7e-28 99.7 9.0 2.1e-28 99.4 9.0 1.1 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30860.1 - 3.7e-12 46.4 0.2 3.7e-12 46.4 0.2 3.1 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B561 PF03188.16 PFH30860.1 - 0.57 10.3 11.5 4.4 7.4 1.1 2.9 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 DUF5083 PF16890.5 PFH30860.1 - 1.3 8.8 4.8 0.39 10.4 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) COX1 PF00115.20 PFH30861.1 - 2.4e-33 115.6 20.7 2.4e-33 115.6 20.7 1.4 1 1 1 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I DPM3 PF08285.11 PFH30861.1 - 1.4 9.2 7.0 0.76 10.0 2.2 2.5 1 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3789 PF12664.7 PFH30861.1 - 2.7 7.8 8.5 0.29 10.9 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) Cytochrom_B_C PF00032.17 PFH30862.1 - 0.0011 19.2 0.9 0.0012 19.1 0.9 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD DUF2721 PF11026.8 PFH30862.1 - 0.41 10.5 5.7 0.48 10.3 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) COX1 PF00115.20 PFH30863.1 - 1.6e-74 251.3 45.1 1.9e-74 251.1 45.1 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF2407_C PF13373.6 PFH30864.1 - 0.09 12.9 1.0 2.6 8.2 0.0 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain DUF981 PF06168.11 PFH30864.1 - 0.3 11.0 8.6 0.49 10.3 8.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF981) Cytochrom_B_C PF00032.17 PFH30865.1 - 6.2e-13 48.9 0.2 6.2e-13 48.9 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30866.1 - 6e-13 49.0 0.2 6e-13 49.0 0.2 1.5 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30868.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30868.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) DUF2407_C PF13373.6 PFH30869.1 - 0.11 12.7 1.0 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrome_B PF00033.19 PFH30870.1 - 3.4e-50 170.5 17.2 5.6e-50 169.8 17.2 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30870.1 - 3.2e-28 98.8 9.3 4.2e-28 98.4 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30870.1 - 4.7e-12 46.1 0.2 4.7e-12 46.1 0.2 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30871.1 - 1.9e-19 69.9 6.4 3.3e-19 69.1 6.4 1.4 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30872.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30872.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Cytochrome_B PF00033.19 PFH30873.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30873.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30873.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30874.1 - 1e-19 70.7 6.2 1.2e-19 70.5 6.2 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30875.1 - 5e-13 49.2 8.4 1.9e-12 47.3 0.2 3.0 4 0 0 4 4 4 2 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30875.1 - 6.3e-07 29.5 5.4 8.4e-07 29.1 5.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrome_B PF00033.19 PFH30876.1 - 1.4e-50 171.8 16.0 2.8e-50 170.8 16.0 1.4 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30876.1 - 7.7e-28 97.6 9.8 1.1e-27 97.1 9.8 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30876.1 - 3.8e-12 46.4 0.3 3.8e-12 46.4 0.3 3.1 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30877.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30878.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30879.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30880.1 - 1e-19 70.7 6.4 1.6e-19 70.1 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD DUF2407_C PF13373.6 PFH30881.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrome_B PF00033.19 PFH30882.1 - 5.6e-58 195.9 21.0 9.6e-58 195.1 21.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30882.1 - 8.8e-28 97.4 9.8 8.8e-28 97.4 9.8 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30882.1 - 5.7e-12 45.8 0.2 5.7e-12 45.8 0.2 3.4 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30882.1 - 0.024 14.8 1.2 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family COX3 PF00510.18 PFH30883.1 - 7.6e-07 29.2 6.0 7.6e-07 29.2 6.0 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III COX3 PF00510.18 PFH30885.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30886.1 - 6.2e-13 48.9 0.2 6.2e-13 48.9 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30887.1 - 1.9e-19 69.8 6.4 3.2e-19 69.1 6.4 1.4 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30889.1 - 3.5e-56 190.0 21.1 3.5e-56 190.0 21.1 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30889.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30889.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD DUF2407_C PF13373.6 PFH30890.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrome_B PF00033.19 PFH30892.1 - 5.6e-58 195.9 21.0 9.6e-58 195.1 21.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30892.1 - 8.8e-28 97.4 9.8 8.8e-28 97.4 9.8 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30892.1 - 5.7e-12 45.8 0.2 5.7e-12 45.8 0.2 3.4 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30892.1 - 0.024 14.8 1.2 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family Cytochrom_B_C PF00032.17 PFH30893.1 - 8.3e-20 71.0 6.4 1e-19 70.8 6.4 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30894.1 - 5.1e-19 68.5 6.3 6.7e-19 68.1 6.3 1.2 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD DUF981 PF06168.11 PFH30895.1 - 0.04 13.8 3.9 0.049 13.5 3.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF981) DUF2407_C PF13373.6 PFH30895.1 - 0.051 13.7 1.3 0.73 10.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30896.1 - 2.6e-18 66.2 6.0 3.1e-18 66.0 6.0 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30897.1 - 4e-55 186.6 20.7 4e-55 186.6 20.7 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30897.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30897.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30898.1 - 1.4e-12 47.8 0.2 1.4e-12 47.8 0.2 2.1 3 0 0 3 3 3 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30898.1 - 4.9e-07 29.8 4.5 6.5e-07 29.5 4.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30899.1 - 4.1e-13 49.5 0.2 4.1e-13 49.5 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD DUF2407_C PF13373.6 PFH30900.1 - 0.098 12.8 1.3 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX1 PF00115.20 PFH30901.1 - 0.0016 17.4 7.5 0.002 17.1 7.5 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF2938 PF11158.8 PFH30901.1 - 0.0084 15.6 0.3 0.016 14.7 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2938) COX3 PF00510.18 PFH30901.1 - 0.019 14.8 7.9 0.035 13.9 7.9 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase subunit III DUF981 PF06168.11 PFH30901.1 - 0.024 14.5 8.4 0.037 13.9 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2407_C PF13373.6 PFH30901.1 - 0.29 11.3 0.9 4.9 7.3 0.0 2.2 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30902.1 - 1.3e-12 47.9 0.2 1.3e-12 47.9 0.2 1.6 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30903.1 - 0.0052 15.7 8.0 0.0067 15.3 8.0 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF981 PF06168.11 PFH30903.1 - 0.024 14.6 8.5 0.039 13.9 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2407_C PF13373.6 PFH30903.1 - 0.24 11.6 1.2 3.1 8.0 0.0 2.2 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX1 PF00115.20 PFH30904.1 - 0.0052 15.7 8.0 0.0067 15.3 8.0 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF981 PF06168.11 PFH30904.1 - 0.024 14.6 8.5 0.039 13.9 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2407_C PF13373.6 PFH30904.1 - 0.24 11.6 1.2 3.1 8.0 0.0 2.2 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrom_B_C PF00032.17 PFH30905.1 - 6.2e-13 48.9 0.2 6.2e-13 48.9 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30906.1 - 2.7e-42 145.1 27.5 2.7e-42 145.1 27.5 2.1 1 1 1 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I COX3 PF00510.18 PFH30906.1 - 0.049 13.5 35.1 0.018 14.9 28.1 3.2 1 1 1 2 2 2 0 Cytochrome c oxidase subunit III DUF3789 PF12664.7 PFH30906.1 - 5.6 6.8 8.5 0.55 10.0 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) COX3 PF00510.18 PFH30907.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30908.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30909.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30909.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30909.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30910.1 - 1.2e-95 320.9 55.1 1.5e-95 320.7 55.1 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30910.1 - 0.13 12.0 3.3 0.73 9.6 3.3 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) COX1 PF00115.20 PFH30911.1 - 1.9e-100 336.7 58.4 2.4e-100 336.4 58.4 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30911.1 - 0.14 11.9 3.3 0.83 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Cytochrom_B_C PF00032.17 PFH30912.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30913.1 - 2.2e-23 83.1 5.3 2.4e-23 82.9 5.3 1.0 1 0 0 1 1 1 1 Cytochrome b/b6/petB Ni_hydr_CYTB PF01292.20 PFH30913.1 - 0.0074 15.9 3.8 0.0083 15.7 3.8 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 PFH30913.1 - 0.049 14.2 7.8 0.12 12.9 7.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4405) Cytochrome_B PF00033.19 PFH30914.1 - 9.5e-51 172.3 16.0 1.7e-50 171.5 16.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30914.1 - 3.4e-28 98.8 9.3 4.5e-28 98.4 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30914.1 - 4.8e-12 46.1 0.2 4.8e-12 46.1 0.2 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30916.1 - 3.6e-56 190.0 19.0 4.4e-56 189.7 19.0 1.0 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30916.1 - 1.7e-22 80.2 9.0 1.7e-22 80.2 9.0 1.7 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB TrbC PF04956.13 PFH30916.1 - 0.15 12.3 5.3 2.1 8.6 2.0 2.5 2 1 0 2 2 2 0 TrbC/VIRB2 family DUF4405 PF14358.6 PFH30916.1 - 1.6 9.3 13.9 0.37 11.4 7.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Cytochrom_B_C PF00032.17 PFH30917.1 - 7.8e-13 48.6 0.2 7.8e-13 48.6 0.2 1.5 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30918.1 - 4.6e-100 335.5 58.8 4.6e-100 335.5 58.8 2.0 1 1 1 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I COX3 PF00510.18 PFH30919.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30920.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30921.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30921.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Cytochrome_B PF00033.19 PFH30922.1 - 7.2e-58 195.5 21.3 1.6e-57 194.4 21.3 1.6 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30922.1 - 1.3e-27 96.9 9.8 1.3e-27 96.9 9.8 1.8 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30922.1 - 4.1e-12 46.3 0.2 4.1e-12 46.3 0.2 3.8 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30922.1 - 0.046 13.9 1.7 1.9 8.8 0.2 2.8 2 0 0 2 2 2 0 TrbC/VIRB2 family DUF5083 PF16890.5 PFH30922.1 - 5.6 6.7 7.5 0.99 9.1 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) DUF981 PF06168.11 PFH30923.1 - 0.17 11.8 11.6 0.27 11.1 11.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF981) DUF2407_C PF13373.6 PFH30924.1 - 0.087 13.0 1.7 1.9 8.6 0.1 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX1 PF00115.20 PFH30925.1 - 6.2e-19 68.2 6.7 6.8e-19 68.0 6.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF2938 PF11158.8 PFH30926.1 - 0.067 12.7 0.1 0.076 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) RIC1 PF07064.13 PFH30927.1 - 1.3e-13 51.0 0.1 2.1e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 RIC1 DUF2474 PF10617.9 PFH30927.1 - 0.075 12.9 1.5 0.22 11.4 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) Kinase-like PF14531.6 PFH30928.1 - 2e-38 132.3 0.0 2.9e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH30928.1 - 6e-08 32.4 0.0 0.0004 19.9 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH30928.1 - 0.00021 20.7 0.0 0.001 18.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PFH30928.1 - 0.0042 16.7 0.0 0.0068 16.0 0.0 1.4 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 PFH30928.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RPAP1_N PF08621.10 PFH30929.1 - 4.3e-07 29.6 4.9 4.3e-07 29.6 4.9 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal RIC1 PF07064.13 PFH30930.1 - 3.1e-14 53.0 1.7 2.3e-13 50.2 0.1 2.3 2 0 0 2 2 2 2 RIC1 RVT_1 PF00078.27 PFH30931.1 - 1.2e-12 47.8 0.2 1.7e-12 47.3 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cytochrom_B_C PF00032.17 PFH30933.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30934.1 - 5.8e-58 195.8 21.0 9.5e-58 195.1 21.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30934.1 - 8.8e-28 97.4 9.8 8.8e-28 97.4 9.8 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30934.1 - 1.2e-11 44.8 0.3 1.2e-11 44.8 0.3 3.4 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30934.1 - 0.023 14.9 1.2 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family Cytochrom_B_C PF00032.17 PFH30935.1 - 2.8e-13 50.0 0.2 3.2e-13 49.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30936.1 - 2.4e-18 66.2 12.1 2.9e-18 66.0 12.1 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DPM3 PF08285.11 PFH30936.1 - 0.081 13.1 3.3 0.31 11.2 3.3 2.1 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) TMEM72 PF16054.5 PFH30936.1 - 0.13 12.0 3.6 0.37 10.5 1.5 2.0 2 0 0 2 2 2 0 Transmembrane protein family 72 Cytochrome_B PF00033.19 PFH30937.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30937.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30937.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30938.1 - 6.2e-13 48.9 0.2 6.2e-13 48.9 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30939.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30940.1 - 1.9e-19 69.8 6.4 3.2e-19 69.1 6.4 1.4 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30941.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30941.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) COX1 PF00115.20 PFH30942.1 - 3.1e-23 82.3 10.6 3.5e-23 82.2 10.6 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF4133 PF13571.6 PFH30942.1 - 5.9 7.3 8.3 6.7 7.1 1.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Cytochrome_B PF00033.19 PFH30943.1 - 2.7e-35 121.9 9.1 2.9e-35 121.8 9.1 1.0 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30943.1 - 1.2e-09 38.4 2.4 1.2e-09 38.4 2.4 1.8 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB DUF1516 PF07457.11 PFH30943.1 - 0.22 11.7 7.5 4.4 7.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) Questin_oxidase PF14027.6 PFH30943.1 - 0.31 10.5 1.8 0.37 10.3 1.8 1.1 1 0 0 1 1 1 0 Questin oxidase-like Cytochrom_B561 PF03188.16 PFH30943.1 - 0.48 10.6 12.1 5.9 7.0 4.8 2.4 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 Ni_hydr_CYTB PF01292.20 PFH30943.1 - 0.62 9.6 13.8 0.051 13.2 4.3 2.1 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF4405 PF14358.6 PFH30943.1 - 0.99 10.0 12.7 0.27 11.8 7.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) DUF4079 PF13301.6 PFH30943.1 - 7.6 6.7 10.2 10 6.2 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) COX1 PF00115.20 PFH30944.1 - 2.2e-45 155.3 25.6 2.4e-45 155.2 25.6 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DHHC PF01529.20 PFH30944.1 - 0.093 12.8 4.5 0.18 11.9 4.5 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase COX1 PF00115.20 PFH30945.1 - 4.8e-100 335.4 58.9 4.8e-100 335.4 58.9 1.3 1 1 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30945.1 - 0.17 11.7 3.3 0.92 9.3 3.3 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Cytochrome_B PF00033.19 PFH30946.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30946.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30946.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30947.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30947.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30947.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30948.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30948.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Cytochrome_B PF00033.19 PFH30949.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30949.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30949.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30950.1 - 8.3e-20 71.0 6.4 1e-19 70.8 6.4 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30951.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30952.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30953.1 - 1.1e-18 67.5 6.4 1.1e-18 67.5 6.4 2.3 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30954.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30954.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Cytochrom_B_C PF00032.17 PFH30955.1 - 1.6e-12 47.6 0.9 1.6e-12 47.6 0.9 1.7 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30956.1 - 1.1e-14 54.1 2.8 1.2e-14 54.1 2.8 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF2407_C PF13373.6 PFH30957.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX1 PF00115.20 PFH30958.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30958.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Cytochrome_B PF00033.19 PFH30959.1 - 1.9e-57 194.2 21.0 1.9e-57 194.2 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30959.1 - 7.6e-28 97.6 8.7 7.6e-28 97.6 8.7 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30959.1 - 1.5e-17 63.7 4.5 1.5e-17 63.7 4.5 3.3 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30960.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30960.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30960.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30961.1 - 5.2e-48 163.4 15.2 8.9e-48 162.6 15.2 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30961.1 - 3.2e-28 98.8 9.3 4.2e-28 98.5 9.3 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30961.1 - 4.6e-12 46.1 0.2 4.6e-12 46.1 0.2 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30962.1 - 6.2e-13 48.9 0.2 6.2e-13 48.9 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30963.1 - 6.2e-13 48.9 0.2 6.2e-13 48.9 0.2 1.4 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30964.1 - 1.2e-74 251.8 45.0 1.4e-74 251.5 45.0 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX3 PF00510.18 PFH30965.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrome_B PF00033.19 PFH30966.1 - 3.7e-35 121.4 13.3 4.1e-35 121.3 13.3 1.0 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30966.1 - 1.9e-23 83.3 9.3 2.1e-23 83.2 9.3 1.0 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrome_B PF00033.19 PFH30967.1 - 5.6e-58 195.9 21.0 9.6e-58 195.1 21.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30967.1 - 8.8e-28 97.4 9.8 8.8e-28 97.4 9.8 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30967.1 - 5.7e-12 45.8 0.2 5.7e-12 45.8 0.2 3.4 2 1 1 3 3 3 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30967.1 - 0.024 14.8 1.2 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family COX3 PF00510.18 PFH30968.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30969.1 - 1.2e-19 70.5 6.4 1.9e-19 69.9 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30970.1 - 4.3e-09 36.6 18.3 1.6e-08 34.7 18.3 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III DUF2407_C PF13373.6 PFH30971.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain Cytochrome_B PF00033.19 PFH30972.1 - 8.2e-58 195.4 21.0 1.4e-57 194.6 21.0 1.3 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30972.1 - 1.3e-27 96.9 9.8 1.3e-27 96.9 9.8 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30972.1 - 4.5e-14 52.6 0.3 4.5e-14 52.6 0.3 3.3 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD TrbC PF04956.13 PFH30972.1 - 0.049 13.9 1.7 1.9 8.8 0.2 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family Cytochrom_B_C PF00032.17 PFH30973.1 - 9.5e-19 67.6 6.4 9.5e-19 67.6 6.4 2.3 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_C PF00032.17 PFH30974.1 - 1.6e-19 70.1 6.4 2.1e-19 69.7 6.4 1.2 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Kinase-like PF14531.6 PFH30975.1 - 1.2e-47 162.7 0.0 1.4e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH30975.1 - 1.6e-19 70.3 0.0 5.4e-18 65.3 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH30975.1 - 0.00041 19.7 0.0 0.0027 17.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 PFH30975.1 - 0.017 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Rv2175c_C PF18367.1 PFH30975.1 - 0.033 14.3 0.1 0.11 12.6 0.1 1.9 1 0 0 1 1 1 0 Rv2175c C-terminal domain of unknown function Pox_ser-thr_kin PF05445.11 PFH30975.1 - 0.24 10.3 0.0 0.48 9.3 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Ion_trans PF00520.31 PFH30976.1 - 3.8e-05 23.0 0.8 5.5e-05 22.5 0.8 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 PFH30976.1 - 0.0061 15.3 1.4 0.0081 14.9 1.4 1.1 1 0 0 1 1 1 1 Polycystin cation channel SecE PF00584.20 PFH30976.1 - 0.1 12.6 4.2 0.18 11.7 4.2 1.4 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex RPAP1_N PF08621.10 PFH30977.1 - 9.1e-08 31.8 4.9 1.8e-07 30.8 4.9 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal Kinase-like PF14531.6 PFH30978.1 - 2e-38 132.3 0.0 2.9e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH30978.1 - 6e-08 32.4 0.0 0.0004 19.9 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH30978.1 - 0.00021 20.7 0.0 0.001 18.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PFH30978.1 - 0.0042 16.7 0.0 0.0068 16.0 0.0 1.4 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 PFH30978.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIC1 PF07064.13 PFH30979.1 - 1.5e-12 47.5 0.1 1.5e-12 47.5 0.1 1.9 2 0 0 2 2 2 1 RIC1 Ion_trans PF00520.31 PFH30980.1 - 2.7e-35 121.8 44.6 2.9e-18 66.0 14.8 2.2 2 0 0 2 2 2 2 Ion transport protein Kinase-like PF14531.6 PFH30981.1 - 5.8e-47 160.4 0.0 7.4e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH30981.1 - 8.8e-20 71.2 0.0 1e-14 54.6 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH30981.1 - 0.0018 17.6 0.0 0.033 13.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Rv2175c_C PF18367.1 PFH30981.1 - 0.0065 16.5 0.1 0.022 14.8 0.1 1.9 1 0 0 1 1 1 1 Rv2175c C-terminal domain of unknown function PIP49_C PF12260.8 PFH30981.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pox_ser-thr_kin PF05445.11 PFH30981.1 - 0.057 12.4 0.0 0.084 11.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ion_trans PF00520.31 PFH30982.1 - 7.9e-43 146.4 22.0 1.3e-21 77.0 12.7 2.2 2 0 0 2 2 2 2 Ion transport protein RPAP1_N PF08621.10 PFH30983.1 - 4.3e-07 29.6 4.9 4.3e-07 29.6 4.9 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal Kinase-like PF14531.6 PFH30984.1 - 1.6e-38 132.7 0.0 2.1e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH30984.1 - 4.3e-08 32.8 0.0 0.00033 20.1 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH30984.1 - 0.00015 21.1 0.0 0.00078 18.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PFH30984.1 - 0.0034 17.0 0.0 0.0052 16.4 0.0 1.4 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 PFH30984.1 - 0.0051 16.8 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIC1 PF07064.13 PFH30985.1 - 1.6e-13 50.6 0.1 2.8e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 RIC1 DUF2474 PF10617.9 PFH30985.1 - 0.098 12.5 1.5 0.27 11.1 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) COX3 PF00510.18 PFH30986.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrom_B_C PF00032.17 PFH30987.1 - 2.2e-15 56.8 5.8 3.4e-15 56.2 5.8 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30988.1 - 7.1e-09 35.0 3.0 7.7e-09 34.9 3.0 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cytochrome_B PF00033.19 PFH30989.1 - 2.7e-35 121.9 9.1 2.9e-35 121.8 9.1 1.0 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30989.1 - 1.2e-09 38.4 2.4 1.2e-09 38.4 2.4 1.8 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB DUF1516 PF07457.11 PFH30989.1 - 0.22 11.7 7.5 4.4 7.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) Questin_oxidase PF14027.6 PFH30989.1 - 0.31 10.5 1.8 0.37 10.3 1.8 1.1 1 0 0 1 1 1 0 Questin oxidase-like Cytochrom_B561 PF03188.16 PFH30989.1 - 0.48 10.6 12.1 5.9 7.0 4.8 2.4 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 Ni_hydr_CYTB PF01292.20 PFH30989.1 - 0.62 9.6 13.8 0.051 13.2 4.3 2.1 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF4405 PF14358.6 PFH30989.1 - 0.99 10.0 12.7 0.27 11.8 7.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) DUF4079 PF13301.6 PFH30989.1 - 7.6 6.7 10.2 10 6.2 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) COX1 PF00115.20 PFH30990.1 - 5.8e-24 84.7 11.3 6.9e-24 84.5 11.3 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cytochrom_B_C PF00032.17 PFH30991.1 - 5.2e-19 68.4 6.4 5.2e-19 68.4 6.4 2.1 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrome_B PF00033.19 PFH30991.1 - 3.1e-14 53.2 2.2 3.1e-14 53.2 2.2 2.4 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30991.1 - 1.8e-11 44.3 1.0 1.8e-11 44.3 1.0 1.9 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB COX1 PF00115.20 PFH30992.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30992.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) DUF2407_C PF13373.6 PFH30993.1 - 0.09 13.0 1.1 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain COX1 PF00115.20 PFH30994.1 - 2e-14 53.3 2.3 2e-14 53.3 2.3 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX1 PF00115.20 PFH30995.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30995.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Cytochrom_B_C PF00032.17 PFH30996.1 - 1.2e-19 70.5 6.4 1.9e-19 69.8 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX3 PF00510.18 PFH30997.1 - 1.2e-08 35.1 18.4 4.6e-08 33.2 18.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrome_B PF00033.19 PFH30998.1 - 1.8e-57 194.3 21.0 1.8e-57 194.3 21.0 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH30998.1 - 1.6e-27 96.6 9.8 1.6e-27 96.6 9.8 2.1 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 PFH30998.1 - 1.3e-18 67.1 6.4 1.3e-18 67.1 6.4 3.2 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX1 PF00115.20 PFH30999.1 - 2.3e-100 336.5 58.7 2.8e-100 336.2 58.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH30999.1 - 0.13 12.0 3.3 0.82 9.4 3.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Cytochrome_B PF00033.19 PFH31000.1 - 1.4e-37 129.3 12.3 1.7e-37 129.1 12.3 1.0 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 PFH31000.1 - 5.4e-10 39.5 4.7 5.4e-10 39.5 4.7 1.8 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.20 PFH31000.1 - 0.23 11.0 13.6 0.056 13.0 4.1 2.1 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Questin_oxidase PF14027.6 PFH31000.1 - 0.39 10.2 1.9 0.49 9.9 1.9 1.1 1 0 0 1 1 1 0 Questin oxidase-like DUF4405 PF14358.6 PFH31000.1 - 1 10.0 13.1 0.3 11.7 7.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) TrbC PF04956.13 PFH31000.1 - 1.6 9.0 7.2 5.6 7.2 1.4 2.5 1 1 1 2 2 2 0 TrbC/VIRB2 family DUF4079 PF13301.6 PFH31000.1 - 8.8 6.5 10.5 12 6.1 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) COX1 PF00115.20 PFH31001.1 - 2.6e-06 26.6 1.5 2.9e-06 26.4 1.5 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cytochrome_B PF00033.19 PFH31002.1 - 6.6e-15 55.4 2.2 1.5e-14 54.3 2.2 1.5 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_C PF00032.17 PFH31002.1 - 1.5e-12 47.7 3.5 2.2e-12 47.1 0.2 2.3 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_N_2 PF13631.6 PFH31002.1 - 4.7e-12 46.2 0.9 5.7e-12 45.9 0.9 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB DUF5083 PF16890.5 PFH31002.1 - 0.19 11.5 2.5 0.34 10.6 2.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5083) Cytochrome_B PF00033.19 PFH31003.1 - 2.9e-20 72.9 4.3 3.3e-20 72.7 4.3 1.0 1 0 0 1 1 1 1 Cytochrome b/b6/petB Ni_hydr_CYTB PF01292.20 PFH31003.1 - 0.054 13.1 1.3 0.082 12.5 1.3 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4405 PF14358.6 PFH31003.1 - 0.35 11.4 5.5 0.97 10.0 5.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4405) COX1 PF00115.20 PFH31004.1 - 3.8e-12 45.8 4.8 4.2e-12 45.7 4.8 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cytochrom_B_C PF00032.17 PFH31005.1 - 0.0011 19.2 0.9 0.0012 19.1 0.9 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD DUF2721 PF11026.8 PFH31005.1 - 0.41 10.5 5.7 0.48 10.3 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) COX3 PF00510.18 PFH31006.1 - 6e-08 32.9 7.8 6e-08 32.9 7.8 1.2 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III COX1 PF00115.20 PFH31007.1 - 4.4e-87 292.7 54.6 6.1e-87 292.3 54.6 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3789 PF12664.7 PFH31007.1 - 0.13 12.0 3.3 0.68 9.7 3.3 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) COX1 PF00115.20 PFH31009.1 - 3.1e-12 46.1 3.8 3.4e-12 46.0 3.8 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cytochrom_B_C PF00032.17 PFH31010.1 - 1.2e-19 70.4 6.4 2e-19 69.8 6.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Kinase-like PF14531.6 PFH31012.1 - 1.6e-38 132.7 0.0 2.1e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH31012.1 - 4.3e-08 32.8 0.0 0.00033 20.1 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31012.1 - 0.00015 21.1 0.0 0.00078 18.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PFH31012.1 - 0.0034 17.0 0.0 0.0052 16.4 0.0 1.4 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 PFH31012.1 - 0.0051 16.8 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIC1 PF07064.13 PFH31013.1 - 9.5e-14 51.4 1.7 4.2e-13 49.3 0.1 2.2 2 0 0 2 2 2 1 RIC1 DUF2474 PF10617.9 PFH31013.1 - 0.15 12.0 1.5 0.39 10.6 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) RPAP1_N PF08621.10 PFH31014.1 - 4.3e-07 29.6 4.9 4.3e-07 29.6 4.9 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal Kinase-like PF14531.6 PFH31015.1 - 1.7e-38 132.6 0.0 2.4e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH31015.1 - 4.8e-08 32.7 0.0 0.00035 20.0 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31015.1 - 0.00017 21.0 0.0 0.00084 18.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PFH31015.1 - 0.0036 16.9 0.0 0.0055 16.3 0.0 1.4 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 PFH31015.1 - 0.005 16.8 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PFH31016.1 - 1.8e-10 40.7 0.0 2.4e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH31016.1 - 0.066 12.6 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain RPAP1_N PF08621.10 PFH31017.1 - 4.3e-07 29.6 4.9 4.3e-07 29.6 4.9 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal RIC1 PF07064.13 PFH31018.1 - 9.5e-14 51.4 1.7 4.2e-13 49.3 0.1 2.2 2 0 0 2 2 2 1 RIC1 DUF2474 PF10617.9 PFH31018.1 - 0.15 12.0 1.5 0.39 10.6 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) Ion_trans PF00520.31 PFH31019.1 - 7.2e-76 254.7 75.1 7.2e-21 74.5 13.1 4.2 4 0 0 4 4 4 4 Ion transport protein Kinase-like PF14531.6 PFH31020.1 - 1.1e-24 87.3 0.0 1.4e-15 57.4 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Pkinase PF00069.25 PFH31020.1 - 3.4e-09 36.5 0.0 9.8e-08 31.7 0.0 2.5 1 1 1 2 2 2 1 Protein kinase domain PIP49_C PF12260.8 PFH31020.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Rv2175c_C PF18367.1 PFH31020.1 - 0.021 14.9 0.4 0.059 13.5 0.1 1.9 2 0 0 2 2 2 0 Rv2175c C-terminal domain of unknown function Pox_ser-thr_kin PF05445.11 PFH31020.1 - 0.17 10.8 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_Tyr PF07714.17 PFH31020.1 - 0.24 10.6 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase CbtA PF09490.10 PFH31021.1 - 0.042 13.6 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) S4 PF01479.25 PFH31022.1 - 1.2e-12 47.3 0.0 2.7e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 PFH31022.1 - 2.9e-07 31.3 2.8 5.4e-07 30.4 2.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_S4 PF00163.19 PFH31025.1 - 1.4e-07 32.4 2.6 1.6e-07 32.1 2.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF5640 PF18692.1 PFH31025.1 - 0.047 13.7 0.8 0.07 13.2 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5640) Kinase-like PF14531.6 PFH31026.1 - 1.1e-47 162.8 0.0 1.4e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH31026.1 - 1.5e-19 70.4 0.0 5.1e-18 65.4 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31026.1 - 0.00039 19.8 0.0 0.0026 17.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 PFH31026.1 - 0.016 14.8 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Rv2175c_C PF18367.1 PFH31026.1 - 0.032 14.3 0.1 0.11 12.7 0.1 1.9 1 0 0 1 1 1 0 Rv2175c C-terminal domain of unknown function Pox_ser-thr_kin PF05445.11 PFH31026.1 - 0.23 10.4 0.0 0.46 9.4 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Ion_trans PF00520.31 PFH31027.1 - 4.8e-32 111.1 40.9 2.8e-17 62.8 12.3 2.1 2 0 0 2 2 2 2 Ion transport protein DUF502 PF04367.13 PFH31027.1 - 0.11 12.3 0.3 0.35 10.8 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF502) Ion_trans PF00520.31 PFH31028.1 - 0.0014 17.9 6.5 0.0026 17.0 6.5 1.4 1 0 0 1 1 1 1 Ion transport protein Kinase-like PF14531.6 PFH31029.1 - 1.1e-47 162.8 0.0 1.4e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH31029.1 - 1.5e-19 70.4 0.0 5.1e-18 65.4 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31029.1 - 0.00039 19.8 0.0 0.0026 17.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 PFH31029.1 - 0.016 14.8 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Rv2175c_C PF18367.1 PFH31029.1 - 0.032 14.3 0.1 0.11 12.7 0.1 1.9 1 0 0 1 1 1 0 Rv2175c C-terminal domain of unknown function Pox_ser-thr_kin PF05445.11 PFH31029.1 - 0.23 10.4 0.0 0.46 9.4 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Ion_trans PF00520.31 PFH31030.1 - 2.9e-10 39.8 12.3 4e-10 39.3 7.9 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 PFH31030.1 - 0.00073 18.3 7.3 0.0011 17.8 7.3 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ribosomal_S3_C PF00189.20 PFH31031.1 - 5.4e-13 49.3 0.1 8.2e-13 48.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain S4 PF01479.25 PFH31032.1 - 1.2e-12 47.3 0.0 2.7e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 PFH31032.1 - 2.9e-07 31.3 2.8 5.4e-07 30.4 2.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Cmc1 PF08583.10 PFH31035.1 - 0.077 13.0 1.8 0.1 12.6 0.5 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 PFH31035.1 - 0.1 12.6 0.4 0.27 11.3 0.4 1.7 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ThiF PF00899.21 PFH31036.1 - 7.1e-60 202.4 0.0 1.6e-36 125.9 0.0 4.9 4 2 0 4 4 4 4 ThiF family UBA_e1_thiolCys PF10585.9 PFH31036.1 - 3.2e-06 27.3 0.0 0.058 13.3 0.0 3.5 3 0 0 3 3 3 2 Ubiquitin-activating enzyme active site Kinase-like PF14531.6 PFH31037.1 - 1.2e-49 169.2 0.0 1.5e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH31037.1 - 1.7e-23 83.4 0.0 1.1e-17 64.3 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31037.1 - 2.5e-06 27.0 0.0 7.3e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 PFH31037.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family CLTH PF10607.9 PFH31038.1 - 4.9e-24 84.9 1.4 6.1e-24 84.6 1.4 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 PFH31038.1 - 8.2e-05 22.4 0.1 0.00021 21.1 0.1 1.7 2 0 0 2 2 2 1 LisH CCAP PF11105.8 PFH31038.1 - 0.075 13.0 0.1 16 5.4 0.0 2.2 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a CBM_20 PF00686.19 PFH31039.1 - 4e-20 71.5 0.1 5.7e-20 71.0 0.1 1.2 1 0 0 1 1 1 1 Starch binding domain DNA_ligase_aden PF01653.18 PFH31041.1 - 1.2e-25 90.3 0.0 1.1e-09 37.9 0.0 4.8 5 0 0 5 5 5 4 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 PFH31041.1 - 1.6e-13 50.3 0.0 2.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain RHD3 PF05879.12 PFH31042.1 - 4.4e-123 412.0 0.0 6e-123 411.5 0.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 PFH31042.1 - 1.6e-05 24.9 0.0 4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.19 PFH31042.1 - 0.00015 21.2 0.4 0.00038 19.8 0.0 1.8 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 PFH31042.1 - 0.00059 19.9 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 PFH31042.1 - 0.026 14.8 0.1 0.17 12.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain PIN_5 PF08745.11 PFH31042.1 - 0.11 11.9 0.2 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 PINc domain ribonuclease PI-PLC-X PF00388.19 PFH31043.1 - 0.17 11.5 0.0 0.44 10.1 0.0 1.6 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain PHC2_SAM_assoc PF16616.5 PFH31044.1 - 0.8 10.5 5.2 0.53 11.1 1.6 2.6 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 ELO PF01151.18 PFH31045.1 - 6.7e-64 215.8 23.3 8.2e-64 215.5 23.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PsbL PF02419.17 PFH31045.1 - 0.22 11.6 2.6 0.36 10.9 0.8 2.4 2 0 0 2 2 2 0 PsbL protein Fun_ATP-synt_8 PF05933.13 PFH31045.1 - 0.75 10.0 6.2 0.32 11.2 0.8 3.0 3 0 0 3 3 3 0 Fungal ATP synthase protein 8 (A6L) Ribosomal_L7Ae PF01248.26 PFH31046.1 - 3.2e-26 90.9 1.1 4.2e-26 90.5 0.6 1.4 1 1 1 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.12 PFH31046.1 - 0.0084 16.4 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding NB-LRR PF12061.8 PFH31046.1 - 0.067 12.5 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Late blight resistance protein R1 EI24 PF07264.11 PFH31047.1 - 0.12 12.7 14.5 0.75 10.0 3.9 2.2 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF4191 PF13829.6 PFH31047.1 - 2.1 7.7 13.2 1.6 8.0 4.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) TauE PF01925.19 PFH31049.1 - 2.3e-26 92.9 19.3 6.6e-15 55.4 0.5 2.6 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE HemY_N PF07219.13 PFH31049.1 - 0.94 9.7 3.9 1.7 8.9 0.2 3.4 2 0 0 2 2 2 0 HemY protein N-terminus DSPc PF00782.20 PFH31050.1 - 7.7e-09 35.5 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CBM_20 PF00686.19 PFH31050.1 - 0.00013 21.7 0.0 0.00047 20.0 0.0 1.9 2 0 0 2 2 2 1 Starch binding domain DUF442 PF04273.13 PFH31050.1 - 0.054 13.6 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Ion_trans PF00520.31 PFH31052.1 - 8.8e-71 238.0 59.6 6.2e-21 74.8 12.6 4.2 4 0 0 4 4 4 4 Ion transport protein DUF5632 PF18646.1 PFH31053.1 - 0.68 10.0 2.7 2.3 8.3 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5632) Sporozoite_P67 PF05642.11 PFH31054.1 - 0.53 8.3 8.6 0.68 7.9 8.6 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen PAP1 PF08601.10 PFH31054.1 - 0.65 9.7 4.8 1 9.0 4.8 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 CCDC24 PF15669.5 PFH31054.1 - 1.2 9.0 9.9 1.7 8.5 9.5 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family CCDC106 PF15794.5 PFH31054.1 - 3.2 7.4 8.1 0.076 12.7 0.6 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 RNA_pol_Rpb2_6 PF00562.28 PFH31055.1 - 7.3e-117 390.7 0.0 4.3e-116 388.2 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 PFH31055.1 - 6e-45 153.3 0.0 9.1e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 PFH31055.1 - 1.8e-31 108.4 0.6 4.6e-31 107.1 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 PFH31055.1 - 6.3e-23 80.8 0.7 1.2e-22 80.0 0.7 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 PFH31055.1 - 7.2e-23 81.2 0.0 1.2e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 PFH31055.1 - 1.6e-20 73.0 0.0 3.1e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 PFH31055.1 - 1.8e-06 28.4 2.3 4.5e-06 27.1 2.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Pox_MCEL PF03291.16 PFH31057.1 - 8.3e-36 123.7 0.0 2.8e-27 95.7 0.0 3.1 2 1 1 3 3 3 2 mRNA capping enzyme Methyltransf_25 PF13649.6 PFH31057.1 - 6.5e-13 49.2 0.1 2.2e-12 47.5 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PFH31057.1 - 3.3e-10 40.5 0.4 1.5e-09 38.4 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PFH31057.1 - 1.2e-09 38.3 0.0 2.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH31057.1 - 1.9e-09 38.2 0.2 7.7e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PFH31057.1 - 1.1e-07 31.7 0.1 2e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_9 PF13454.6 PFH31057.1 - 0.0091 16.0 0.2 2.7 7.9 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding CMAS PF02353.20 PFH31057.1 - 0.021 14.1 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CheR PF01739.18 PFH31057.1 - 0.022 14.3 0.0 0.076 12.5 0.0 1.9 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain AP2 PF00847.20 PFH31058.1 - 1.8e-10 40.9 0.2 7e-10 39.0 0.2 2.1 1 0 0 1 1 1 1 AP2 domain Peptidase_M3 PF01432.20 PFH31060.1 - 6.6e-52 177.3 0.0 7.8e-25 88.0 0.0 3.1 2 1 0 2 2 2 2 Peptidase family M3 AAA_26 PF13500.6 PFH31061.1 - 0.034 14.0 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DNA_pol3_finger PF17657.1 PFH31061.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit finger domain PDEase_I PF00233.19 PFH31062.1 - 2.8e-59 200.7 0.9 1.2e-58 198.7 0.9 1.9 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Vfa1 PF08432.10 PFH31062.1 - 2.2 8.6 5.9 3.9 7.8 5.9 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Cation_ATPase_C PF00689.21 PFH31062.1 - 9.4 5.9 11.0 2.2 7.9 2.2 2.9 3 0 0 3 3 3 0 Cation transporting ATPase, C-terminus Hexapep PF00132.24 PFH31064.1 - 6.8e-10 38.3 4.0 0.0046 16.6 0.1 4.2 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 PFH31064.1 - 0.0029 15.8 0.0 0.0043 15.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 PFH31064.1 - 0.015 15.1 8.2 0.054 13.3 0.0 2.9 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 PFH31064.1 - 0.21 10.5 0.0 0.41 9.5 0.0 1.4 1 0 0 1 1 1 0 L-fucokinase LSM PF01423.22 PFH31065.1 - 9.8e-19 66.8 0.1 1.3e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PFH31065.1 - 0.036 14.2 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain MmlI PF09448.10 PFH31065.1 - 0.16 12.4 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase Menin PF05053.13 PFH31066.1 - 1.6 7.0 10.4 0.056 11.8 1.2 2.1 2 0 0 2 2 2 0 Menin Alpha_adaptinC2 PF02883.20 PFH31067.1 - 4.6e-09 36.6 0.0 9.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.16 PFH31067.1 - 1.7e-06 28.2 0.0 2.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain TMF_TATA_bd PF12325.8 PFH31067.1 - 0.0059 16.8 2.6 0.0059 16.8 2.6 2.7 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF3496 PF12001.8 PFH31067.1 - 0.36 11.2 2.4 0.82 10.1 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) MerR-DNA-bind PF09278.11 PFH31067.1 - 7.7 7.1 13.5 11 6.6 2.9 3.6 3 0 0 3 3 3 0 MerR, DNA binding DUF4455 PF14643.6 PFH31068.1 - 8.8e-14 51.0 26.0 8.8e-14 51.0 26.0 4.3 4 0 0 4 4 4 2 Domain of unknown function (DUF4455) LOH1CR12 PF10158.9 PFH31068.1 - 2.3 8.2 8.8 0.16 12.0 2.1 2.6 2 0 0 2 2 2 0 Tumour suppressor protein Dus PF01207.17 PFH31070.1 - 7.6e-23 81.1 0.0 2.2e-11 43.4 0.0 4.1 4 0 0 4 4 4 4 Dihydrouridine synthase (Dus) SMK-1 PF04802.15 PFH31071.1 - 4.6e-21 75.5 1.1 4.6e-21 75.5 1.1 1.8 3 0 0 3 3 3 1 Component of IIS longevity pathway SMK-1 Cnd3 PF12719.7 PFH31071.1 - 0.016 14.4 0.7 0.14 11.3 0.5 2.1 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Pkinase PF00069.25 PFH31072.1 - 2.6e-59 200.8 0.0 2.8e-39 135.1 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31072.1 - 1.1e-28 100.3 0.0 6.4e-20 71.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PFH31072.1 - 0.0023 17.3 0.1 0.15 11.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 PFH31072.1 - 0.0028 17.6 0.1 0.0096 15.9 0.1 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PFH31072.1 - 0.0036 16.3 0.1 0.0055 15.7 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain SNase PF00565.17 PFH31074.1 - 0.031 14.7 0.4 2.5 8.6 0.2 2.6 1 1 0 2 2 2 0 Staphylococcal nuclease homologue DUF1971 PF09313.11 PFH31074.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Asp PF00026.23 PFH31076.1 - 3.9e-50 171.0 0.0 6.8e-50 170.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 PFH31076.1 - 2e-07 31.4 0.0 2e-05 24.9 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal DUF4926 PF16277.5 PFH31076.1 - 0.17 11.3 0.0 0.39 10.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) Sugar_tr PF00083.24 PFH31077.1 - 1.3e-85 287.9 21.4 2.2e-85 287.2 21.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PFH31077.1 - 1.9e-25 89.6 32.6 1.9e-23 83.0 26.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RELT PF12606.8 PFH31077.1 - 7.5 5.6 7.0 1.1 8.3 0.0 3.0 3 0 0 3 3 3 0 Tumour necrosis factor receptor superfamily member 19 Amino_oxidase PF01593.24 PFH31079.1 - 1.4e-12 47.7 0.0 2.7e-11 43.4 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PFH31079.1 - 1e-05 25.7 0.9 0.22 11.7 0.0 3.4 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 PFH31079.1 - 0.015 14.6 0.2 0.17 11.2 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase_Tyr PF07714.17 PFH31080.1 - 8e-38 130.2 0.0 2.5e-27 95.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PFH31080.1 - 3.7e-35 121.6 0.0 2.2e-20 73.1 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain RRM_1 PF00076.22 PFH31082.1 - 2.1e-17 62.7 0.0 2.9e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PFH31082.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 PFH31082.1 - 0.019 14.6 0.0 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain RRM_occluded PF16842.5 PFH31082.1 - 0.038 13.9 0.0 0.066 13.1 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif GRDP-like PF07173.12 PFH31083.1 - 0.022 15.4 0.0 0.044 14.4 0.0 1.5 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like Taxilin PF09728.9 PFH31083.1 - 0.071 12.3 0.4 0.14 11.3 0.4 1.5 1 0 0 1 1 1 0 Myosin-like coiled-coil protein CLZ PF16526.5 PFH31083.1 - 0.16 12.3 0.9 0.5 10.8 0.9 1.8 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MACPF PF01823.19 PFH31084.1 - 2.6e-46 158.4 0.1 2.6e-46 158.4 0.1 1.8 2 0 0 2 2 2 1 MAC/Perforin domain LCAT PF02450.15 PFH31085.1 - 5.5e-38 131.1 0.0 6.4e-34 117.8 0.0 2.2 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 PFH31085.1 - 0.041 13.4 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) NAD_binding_2 PF03446.15 PFH31086.1 - 9e-34 116.9 0.4 3.3e-32 111.8 0.4 2.5 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 PFH31086.1 - 1.9e-28 99.2 0.0 3.7e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 PFH31086.1 - 0.049 13.0 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 PFH31086.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 PFH31086.1 - 0.16 11.5 0.0 0.77 9.3 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CK_II_beta PF01214.18 PFH31087.1 - 1.1e-63 214.4 0.0 1.3e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF1126 PF06565.12 PFH31091.1 - 1.7e-85 281.7 8.8 3.8e-35 119.9 0.7 4.0 4 0 0 4 4 4 3 DUF1126 PH-like domain WD40 PF00400.32 PFH31092.1 - 1.3e-22 79.6 9.7 1.8e-05 25.4 0.5 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH31092.1 - 8.1e-11 42.1 0.5 0.11 12.8 0.0 5.1 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PFH31092.1 - 3.4e-06 27.1 0.1 1.1 9.1 0.0 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 PFH31092.1 - 0.0011 17.4 0.0 0.0028 16.0 0.0 1.6 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 PFH31092.1 - 0.011 14.7 0.0 4.7 6.1 0.0 3.2 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Telomere_Sde2_2 PF13297.6 PFH31093.1 - 3.1e-19 68.4 0.0 5.9e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 PFH31093.1 - 2.1e-12 47.2 0.1 2.1e-12 47.2 0.1 3.2 3 0 0 3 3 3 1 Silencing defective 2 N-terminal ubiquitin domain FAM176 PF14851.6 PFH31093.1 - 0.054 13.2 15.2 0.61 9.7 5.0 2.4 2 0 0 2 2 2 0 FAM176 family Torsin PF06309.11 PFH31093.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Torsin TMEM171 PF15471.6 PFH31093.1 - 0.29 10.1 6.2 0.74 8.7 6.2 1.7 1 1 0 1 1 1 0 Transmembrane protein family 171 PBP1_TM PF14812.6 PFH31093.1 - 8.3 6.9 8.6 2.9 8.3 3.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DHHC PF01529.20 PFH31094.1 - 6.9e-25 87.7 4.9 6.9e-25 87.7 4.9 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 PFH31094.1 - 4.2e-21 75.3 0.2 2.2e-06 28.2 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PFH31094.1 - 6.2e-14 52.2 4.4 5.4e-07 30.0 0.2 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH31094.1 - 9.2e-13 47.2 10.7 3.6e-05 23.8 0.0 6.0 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 PFH31094.1 - 4.6e-12 45.9 7.1 6.3e-05 23.2 0.0 5.7 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 PFH31094.1 - 1.9e-10 40.7 3.0 0.00016 21.9 0.1 5.5 6 0 0 6 6 6 2 Ankyrin repeat Transket_pyr PF02779.24 PFH31096.1 - 7.7e-45 152.7 0.0 1.3e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PFH31096.1 - 3.9e-35 120.4 0.1 8.2e-35 119.4 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain PP2C PF00481.21 PFH31098.1 - 3.1e-36 125.3 0.0 2.9e-22 79.5 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 PFH31098.1 - 0.0003 20.5 0.0 0.011 15.4 0.0 2.9 2 1 0 2 2 2 1 Protein phosphatase 2C His_Phos_1 PF00300.22 PFH31101.1 - 1.9e-09 37.5 0.3 0.00025 20.8 0.0 3.4 2 2 1 3 3 3 2 Histidine phosphatase superfamily (branch 1) CDP-OH_P_transf PF01066.21 PFH31103.1 - 1.8e-10 41.4 0.1 1e-09 39.0 0.0 2.4 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase OTU PF02338.19 PFH31104.1 - 2.8e-06 27.8 0.0 1.5e-05 25.5 0.0 2.0 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PFH31104.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase C65 Otubain DUF3591 PF12157.8 PFH31106.1 - 1.1e-28 100.1 0.0 3.5e-14 52.3 0.0 3.5 2 2 0 2 2 2 2 Protein of unknown function (DUF3591) Bromodomain PF00439.25 PFH31106.1 - 2.5e-17 62.7 0.1 5e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 Bromodomain zf-CCHC PF00098.23 PFH31106.1 - 0.0036 17.3 0.3 0.0092 16.0 0.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 PFH31106.1 - 0.0044 16.8 2.2 0.012 15.4 2.2 1.8 1 0 0 1 1 1 1 Zinc knuckle Fibin PF15819.5 PFH31106.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Fin bud initiation factor homologue zf-CCHC_2 PF13696.6 PFH31106.1 - 0.26 11.2 1.2 0.56 10.1 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle PI3_PI4_kinase PF00454.27 PFH31111.1 - 2.2e-36 125.9 0.0 4.4e-36 125.0 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase AMP-binding PF00501.28 PFH31112.1 - 8.8e-19 67.4 0.0 4.5e-15 55.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Arf PF00025.21 PFH31113.1 - 3e-78 261.3 0.1 3.4e-78 261.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PFH31113.1 - 1.9e-14 53.9 0.0 2.7e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PFH31113.1 - 3.4e-14 52.7 0.0 4.2e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 PFH31113.1 - 4.8e-13 49.0 0.0 5.1e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 PFH31113.1 - 2.3e-12 46.8 0.8 2.6e-08 33.4 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 PFH31113.1 - 2.7e-11 43.3 0.0 3.3e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PFH31113.1 - 1.1e-05 25.4 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 PFH31113.1 - 0.007 15.7 0.2 0.014 14.7 0.1 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Peptidase_C1 PF00112.23 PFH31114.1 - 3.1e-35 122.3 2.8 5.1e-35 121.6 2.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.11 PFH31114.1 - 7.7e-16 58.5 0.0 2.4e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.15 PFH31114.1 - 0.062 12.1 2.5 0.096 11.4 2.5 1.2 1 0 0 1 1 1 0 Peptidase C1-like family SET PF00856.28 PFH31115.1 - 1.3e-10 42.0 0.0 2.5e-09 37.7 0.0 2.5 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 PFH31115.1 - 2e-08 34.2 9.1 1.3e-07 31.6 9.1 2.6 1 0 0 1 1 1 1 MYND finger Cyt-b5 PF00173.28 PFH31116.1 - 4.2e-21 74.9 0.0 5.7e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MscS_TM PF12794.7 PFH31117.1 - 0.22 10.4 3.0 0.4 9.5 3.0 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Coq4 PF05019.13 PFH31119.1 - 2.3e-59 200.4 0.0 1.6e-53 181.3 0.0 2.1 2 0 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Herpes_pp85 PF04637.12 PFH31122.1 - 0.27 9.6 1.7 0.42 9.0 1.7 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Tubulin PF00091.25 PFH31123.1 - 1e-49 169.4 0.0 1.4e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PFH31123.1 - 5.7e-12 45.9 0.0 9e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PFH31123.1 - 0.031 14.6 0.1 0.065 13.6 0.1 1.5 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain PP2C PF00481.21 PFH31126.1 - 4.3e-06 26.5 0.0 8.8e-05 22.3 0.0 2.5 3 0 0 3 3 3 1 Protein phosphatase 2C DNA_pol_A_exo1 PF01612.20 PFH31127.1 - 8.9e-14 51.6 0.0 1.9e-11 44.0 0.0 2.6 3 0 0 3 3 3 2 3'-5' exonuclease S10_plectin PF03501.15 PFH31128.1 - 9e-42 141.1 0.4 1.1e-41 140.8 0.4 1.1 1 0 0 1 1 1 1 Plectin/S10 domain SRP72 PF08492.12 PFH31129.1 - 2.7e-14 53.3 3.6 6.2e-14 52.2 3.6 1.6 1 0 0 1 1 1 1 SRP72 RNA-binding domain SRP_TPR_like PF17004.5 PFH31129.1 - 2.6e-11 43.6 0.6 4.7e-09 36.3 0.3 2.9 2 1 0 2 2 2 1 Putative TPR-like repeat TPR_12 PF13424.6 PFH31129.1 - 3.3e-08 33.7 53.6 0.0016 18.7 6.8 9.2 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 PFH31129.1 - 3.5e-07 29.8 41.0 0.13 12.4 0.1 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 PFH31129.1 - 0.00064 19.7 8.9 0.18 12.1 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 PFH31129.1 - 0.0011 19.5 61.6 1.8 9.2 2.3 10.0 5 4 5 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 PFH31129.1 - 0.0027 18.4 69.5 0.45 11.5 0.3 11.2 9 2 4 13 13 11 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH31129.1 - 0.0029 17.8 4.6 0.0029 17.8 4.6 5.1 6 1 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 PFH31129.1 - 0.0052 17.3 82.8 0.024 15.3 0.1 13.0 12 3 2 14 14 14 4 Tetratricopeptide repeat NARP1 PF12569.8 PFH31129.1 - 0.0054 15.7 1.1 0.026 13.5 0.4 2.3 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 PFH31129.1 - 0.69 10.1 28.1 4 7.7 0.2 8.3 10 0 0 10 10 10 0 Tetratricopeptide repeat cEGF PF12662.7 PFH31130.1 - 0.029 14.3 21.0 0.042 13.8 1.3 4.6 4 0 0 4 4 4 0 Complement Clr-like EGF-like Podoplanin PF05808.11 PFH31130.1 - 0.077 13.1 0.8 0.13 12.3 0.8 1.3 1 0 0 1 1 1 0 Podoplanin hEGF PF12661.7 PFH31130.1 - 0.16 12.7 33.6 0.25 12.0 5.1 5.5 5 0 0 5 5 5 0 Human growth factor-like EGF FXa_inhibition PF14670.6 PFH31130.1 - 5.8 7.3 41.2 0.58 10.5 3.7 5.4 3 2 1 4 4 4 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 PFH31131.1 - 2.7e-07 30.4 22.8 0.0074 16.2 0.2 4.7 4 0 0 4 4 4 3 Complement Clr-like EGF-like hEGF PF12661.7 PFH31131.1 - 0.00051 20.6 37.1 0.0031 18.1 2.2 5.3 4 0 0 4 4 4 3 Human growth factor-like EGF EGF PF00008.27 PFH31131.1 - 0.0072 16.6 56.3 0.017 15.4 7.4 5.4 5 0 0 5 5 5 4 EGF-like domain EGF_3 PF12947.7 PFH31131.1 - 0.018 15.2 10.8 0.018 15.2 10.8 5.5 6 0 0 6 6 6 0 EGF domain Podoplanin PF05808.11 PFH31131.1 - 0.18 11.9 0.0 0.18 11.9 0.0 2.5 3 0 0 3 3 3 0 Podoplanin Plasmod_Pvs28 PF06247.11 PFH31131.1 - 0.47 10.8 37.9 1.1 9.6 4.3 4.8 3 1 1 4 4 4 0 Pvs28 EGF domain FXa_inhibition PF14670.6 PFH31131.1 - 4.6 7.6 50.1 0.52 10.6 2.6 5.6 3 2 1 4 4 4 0 Coagulation Factor Xa inhibitory site F-box-like PF12937.7 PFH31132.1 - 3.1e-05 23.8 0.3 5.7e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 F-box-like DUF826 PF05696.11 PFH31132.1 - 0.1 12.7 0.4 0.32 11.1 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF826) Bap31 PF05529.12 PFH31133.1 - 0.00076 19.4 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region BatD PF13584.6 PFH31133.1 - 0.14 10.9 0.3 0.18 10.6 0.3 1.1 1 0 0 1 1 1 0 Oxygen tolerance PGA2 PF07543.12 PFH31134.1 - 0.031 14.3 3.2 0.046 13.7 3.2 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2749 PF10907.8 PFH31134.1 - 0.96 9.7 4.1 0.36 11.0 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) LSM PF01423.22 PFH31135.1 - 1.6e-16 59.7 0.1 2.3e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 PFH31135.1 - 0.0084 15.7 0.0 0.016 14.9 0.0 1.6 1 1 0 1 1 1 1 Hfq protein AAA_2 PF07724.14 PFH31139.1 - 2.7e-56 190.4 0.0 4e-52 176.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 PFH31139.1 - 1.1e-32 112.1 1.1 1.1e-32 112.1 1.1 3.2 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 PFH31139.1 - 5.5e-26 90.4 0.2 3.3e-25 87.9 0.2 2.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 PFH31139.1 - 2e-25 89.8 0.0 2.6e-13 50.5 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 PFH31139.1 - 9.3e-22 76.9 0.1 9.5e-12 44.9 0.0 2.7 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 PFH31139.1 - 3.7e-18 65.9 0.1 2.7e-12 46.8 0.0 4.0 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PFH31139.1 - 2.4e-10 41.1 1.3 0.00018 22.0 0.1 4.2 4 1 1 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 PFH31139.1 - 1.2e-07 31.6 0.0 1.8e-05 24.5 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 PFH31139.1 - 1e-06 29.3 0.0 0.014 16.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 PFH31139.1 - 1.9e-06 27.7 0.1 0.15 11.8 0.0 3.7 4 0 0 4 4 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 PFH31139.1 - 3.9e-06 26.9 0.0 0.1 12.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 PFH31139.1 - 7.3e-06 26.3 5.3 0.012 15.9 0.0 4.6 4 2 0 4 4 3 2 AAA domain Roc PF08477.13 PFH31139.1 - 5e-05 23.5 0.1 0.35 11.1 0.0 2.9 3 0 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 PFH31139.1 - 0.00034 20.2 0.0 0.27 10.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 PFH31139.1 - 0.00034 20.6 0.0 0.29 11.0 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 PFH31139.1 - 0.00038 19.9 0.1 1 8.7 0.1 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 PFH31139.1 - 0.00041 20.3 0.1 2.1 8.3 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_24 PF13479.6 PFH31139.1 - 0.00062 19.5 0.0 0.26 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 PFH31139.1 - 0.00077 19.6 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 Torsin RNA_helicase PF00910.22 PFH31139.1 - 0.0012 19.2 0.0 1.2 9.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 PFH31139.1 - 0.0013 18.7 0.0 2.6 8.1 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 PFH31139.1 - 0.0016 18.7 0.1 1.8 8.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 PFH31139.1 - 0.0017 18.3 5.6 2.2 8.1 0.0 4.5 3 2 2 6 6 5 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 PFH31139.1 - 0.0069 16.9 0.4 1.4 9.4 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_3 PF07726.11 PFH31139.1 - 0.0095 15.8 0.0 2.6 7.9 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 PFH31139.1 - 0.014 15.0 0.0 0.23 11.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 PFH31139.1 - 0.015 15.6 0.1 0.71 10.2 0.0 3.2 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 PFH31139.1 - 0.017 14.4 0.2 2.1 7.6 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin ATP_bind_1 PF03029.17 PFH31139.1 - 0.047 13.5 0.0 0.92 9.2 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 PFH31139.1 - 0.052 13.5 1.8 21 5.0 0.0 3.8 4 0 0 4 4 4 0 NTPase Bac_DnaA PF00308.18 PFH31139.1 - 0.056 13.3 0.0 4 7.2 0.0 3.2 3 0 0 3 3 3 0 Bacterial dnaA protein ResIII PF04851.15 PFH31139.1 - 0.071 13.1 0.0 7.1 6.6 0.0 3.6 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit betaPIX_CC PF16523.5 PFH31139.1 - 0.14 12.0 7.4 0.17 11.7 5.4 2.3 2 0 0 2 2 1 0 betaPIX coiled coil FAM76 PF16046.5 PFH31139.1 - 0.14 11.4 2.9 0.29 10.5 2.9 1.5 1 0 0 1 1 1 0 FAM76 protein AAA_6 PF12774.7 PFH31139.1 - 0.24 10.3 0.8 6.7 5.6 0.0 3.0 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region SRP54 PF00448.22 PFH31139.1 - 0.35 10.5 1.8 5.1 6.7 0.0 3.2 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain MnmE_helical PF12631.7 PFH31139.1 - 4.4 7.4 5.5 24 5.0 5.5 2.3 1 1 0 1 1 1 0 MnmE helical domain TPR_MLP1_2 PF07926.12 PFH31139.1 - 9.3 6.3 15.0 9.1 6.4 12.4 2.3 2 1 0 2 2 1 0 TPR/MLP1/MLP2-like protein EELM2 PF15863.5 PFH31140.1 - 2.2e-69 233.0 0.1 3.1e-69 232.5 0.1 1.2 1 0 0 1 1 1 1 Extended EGL-27 and MTA1 homology domain IMCp PF12314.8 PFH31141.1 - 4.1e-22 78.3 49.5 1.8e-20 73.0 32.3 4.3 1 1 3 4 4 4 3 Inner membrane complex protein LCM PF04072.14 PFH31142.1 - 7.3e-28 97.8 0.1 1.8e-27 96.5 0.0 1.6 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase DUF3248 PF11609.8 PFH31142.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) Phage_holin_3_5 PF16085.5 PFH31143.1 - 0.11 12.6 0.0 35 4.6 0.0 4.4 4 0 0 4 4 4 0 Bacteriophage holin Hol, superfamily III MobB PF03205.14 PFH31143.1 - 0.36 10.7 1.5 16 5.4 0.0 4.0 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B HECT PF00632.25 PFH31145.1 - 3.5e-100 335.4 0.0 4.6e-100 335.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) YscK PF06578.12 PFH31145.1 - 0.0082 15.7 0.3 0.018 14.5 0.3 1.5 1 0 0 1 1 1 1 YOP proteins translocation protein K (YscK) Pkinase PF00069.25 PFH31146.1 - 9.1e-43 146.5 0.0 1.2e-42 146.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31146.1 - 1.2e-17 64.1 0.0 1.8e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PFH31146.1 - 2.5e-06 26.6 0.0 3.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PFH31146.1 - 0.026 13.9 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DAGAT PF03982.13 PFH31147.1 - 6.3e-34 117.2 0.0 7.7e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DAGAT PF03982.13 PFH31149.1 - 2e-28 99.2 0.0 2.3e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DHHC PF01529.20 PFH31150.1 - 8.3e-37 126.3 12.2 8.3e-37 126.3 12.2 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 PFH31150.1 - 3.7 7.7 5.8 3.3 7.9 4.3 1.7 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger PPR_2 PF13041.6 PFH31151.1 - 3e-55 184.2 7.1 1.3e-13 50.9 0.1 7.8 3 2 5 8 8 8 7 PPR repeat family PPR PF01535.20 PFH31151.1 - 2.3e-45 149.7 11.7 8.4e-06 25.7 0.0 9.4 9 0 0 9 9 9 7 PPR repeat PPR_1 PF12854.7 PFH31151.1 - 1.1e-39 133.7 0.1 5.3e-09 35.6 0.0 7.0 7 0 0 7 7 7 6 PPR repeat PPR_3 PF13812.6 PFH31151.1 - 9e-35 118.6 0.3 2.2e-11 43.7 0.1 6.1 4 2 2 6 6 6 5 Pentatricopeptide repeat domain PPR_long PF17177.4 PFH31151.1 - 8.3e-21 74.3 5.6 1.2e-15 57.5 0.0 3.7 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 PFH31151.1 - 3.7e-06 26.8 0.0 1.1 9.1 0.0 4.0 2 1 1 4 4 4 2 Mitochondrial ATPase expression MRP-S27 PF10037.9 PFH31151.1 - 0.28 10.0 0.1 0.98 8.2 0.1 1.8 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Adeno_knob PF00541.17 PFH31151.1 - 8.1 6.1 5.9 26 4.5 3.1 2.3 2 0 0 2 2 2 0 Adenoviral fibre protein (knob domain) TPR_1 PF00515.28 PFH31152.1 - 3e-52 172.4 35.8 1.4e-07 31.0 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 PFH31152.1 - 1.7e-44 146.3 33.1 1.3e-05 24.9 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.6 PFH31152.1 - 9.2e-26 89.3 22.1 4.2e-08 32.8 0.6 7.6 6 2 2 8 8 8 5 TPR repeat TPR_14 PF13428.6 PFH31152.1 - 4e-19 67.7 6.2 0.13 13.1 0.1 8.3 5 3 2 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 PFH31152.1 - 1.8e-17 63.4 18.7 4.3e-08 33.3 0.6 7.5 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 PFH31152.1 - 1.3e-15 56.5 10.4 0.0078 16.5 0.3 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 PFH31152.1 - 5.4e-15 54.3 29.1 0.029 14.5 0.3 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat STI1 PF17830.1 PFH31152.1 - 7.2e-15 54.7 11.6 4.1e-10 39.4 1.9 3.4 2 0 0 2 2 2 2 STI1 domain TPR_19 PF14559.6 PFH31152.1 - 1.7e-12 47.6 28.2 0.0018 18.7 1.1 7.0 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 PFH31152.1 - 3.8e-11 43.5 20.9 0.0012 19.5 0.1 7.1 7 2 1 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 PFH31152.1 - 2.4e-10 40.4 0.2 0.3 11.3 0.0 5.4 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 PFH31152.1 - 4e-10 39.0 14.1 0.0027 17.6 0.1 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PFH31152.1 - 2.2e-07 30.8 20.3 0.11 12.6 0.2 7.8 6 2 2 8 8 8 2 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 PFH31152.1 - 0.00035 20.7 11.8 1.3 9.1 2.1 4.8 3 3 2 5 5 5 2 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 PFH31152.1 - 0.00051 19.8 21.4 0.077 12.9 0.3 7.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_20 PF14561.6 PFH31152.1 - 0.04 14.3 6.0 6 7.3 0.0 4.6 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH31152.1 - 0.045 14.4 25.6 5.5 7.8 0.2 8.5 8 1 0 9 9 9 0 Tetratricopeptide repeat P16-Arc PF04699.14 PFH31152.1 - 0.76 10.3 8.7 0.25 11.8 2.8 2.8 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Miga PF10265.9 PFH31152.1 - 1.1 8.1 13.9 2.1 7.2 13.6 1.7 1 1 0 1 1 1 0 Mitoguardin DUF2935 PF11155.8 PFH31152.1 - 2 8.8 6.5 1.4 9.3 1.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) ChAPs PF09295.10 PFH31152.1 - 4.7 6.1 9.0 5.5 5.9 0.1 3.5 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_E PF04733.14 PFH31152.1 - 7.2 5.9 14.1 0.35 10.2 1.0 3.9 3 1 2 5 5 5 0 Coatomer epsilon subunit AAA PF00004.29 PFH31154.1 - 2.7e-18 66.7 0.1 2.3e-15 57.2 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PFH31154.1 - 3.2e-05 24.4 2.0 0.028 14.8 0.5 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 PFH31154.1 - 0.0029 17.8 0.1 0.77 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 PFH31154.1 - 0.0033 17.4 0.3 0.89 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 PFH31154.1 - 0.0052 16.6 0.1 1.3 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_18 PF13238.6 PFH31154.1 - 0.01 16.4 0.2 3.2 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 PFH31154.1 - 0.013 15.3 0.1 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PFH31154.1 - 0.013 15.7 0.3 0.1 12.8 0.0 2.7 3 1 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 PFH31154.1 - 0.013 14.8 0.0 0.038 13.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 PFH31154.1 - 0.015 15.1 0.2 0.074 12.8 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 PFH31154.1 - 0.015 15.3 0.0 0.51 10.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 PFH31154.1 - 0.015 15.0 0.0 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 PFH31154.1 - 0.021 14.8 1.1 0.4 10.6 0.1 2.5 2 0 0 2 2 2 0 NACHT domain TIP49 PF06068.13 PFH31154.1 - 0.026 13.7 0.1 0.054 12.7 0.1 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 PFH31154.1 - 0.03 14.4 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 PFH31154.1 - 0.18 12.3 0.1 9.6 6.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 PFH31154.1 - 0.19 11.2 1.5 4.5 6.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain Dpy-30 PF05186.13 PFH31155.1 - 0.00016 21.3 2.0 0.27 11.0 0.4 2.5 2 0 0 2 2 2 2 Dpy-30 motif Ribosomal_L1 PF00687.21 PFH31156.1 - 1.2e-25 90.5 0.0 1.7e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SAE2 PF08573.10 PFH31157.1 - 0.011 16.9 1.0 0.011 16.9 1.0 4.4 5 0 0 5 5 5 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Arm PF00514.23 PFH31158.1 - 4.3e-96 312.4 19.3 2.5e-14 52.7 0.0 8.8 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PFH31158.1 - 1.2e-26 92.8 11.2 7.1e-09 36.0 0.1 7.5 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 PFH31158.1 - 5.3e-23 81.2 2.9 4.8e-07 30.1 0.0 5.4 2 2 3 5 5 5 5 HEAT repeats HEAT PF02985.22 PFH31158.1 - 2.8e-20 70.7 7.7 1.8e-05 24.6 0.0 8.8 9 0 0 9 9 9 3 HEAT repeat Arm_3 PF16186.5 PFH31158.1 - 8.2e-18 63.7 0.4 2.5e-17 62.2 0.4 1.8 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 PFH31158.1 - 1.4e-13 51.0 0.0 4.5e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 Importin beta binding domain Arm_2 PF04826.13 PFH31158.1 - 3.1e-08 33.4 0.0 0.089 12.2 0.0 3.9 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 PFH31158.1 - 2.4e-07 30.9 0.0 0.3 11.2 0.0 4.5 4 0 0 4 4 4 1 V-ATPase subunit H Cnd1 PF12717.7 PFH31158.1 - 1.2e-06 28.7 0.0 0.064 13.3 0.1 4.0 1 1 3 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 PFH31158.1 - 2.1e-05 24.4 0.0 0.037 14.0 0.0 3.5 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Adaptin_N PF01602.20 PFH31158.1 - 4.1e-05 22.3 0.0 0.00047 18.8 0.0 2.7 1 1 0 1 1 1 1 Adaptin N terminal region NopRA1 PF16201.5 PFH31158.1 - 0.002 17.7 0.0 1.1 8.8 0.0 3.9 2 1 1 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 PFH31158.1 - 0.0041 17.3 1.2 0.63 10.3 0.0 4.0 4 1 0 4 4 3 1 Rapamycin-insensitive companion of mTOR, domain 5 Gcn1_N PF12074.8 PFH31158.1 - 0.0052 16.1 0.1 1.6 8.0 0.0 2.3 2 0 0 2 2 2 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT_PBS PF03130.16 PFH31158.1 - 0.0084 16.7 13.1 0.32 11.8 0.1 7.2 8 1 0 8 8 6 1 PBS lyase HEAT-like repeat V-ATPase_H_N PF03224.14 PFH31158.1 - 0.012 14.9 0.1 5.3 6.2 0.0 3.1 2 1 1 3 3 3 0 V-ATPase subunit H DCB PF16213.5 PFH31158.1 - 0.018 14.7 0.7 0.069 12.8 0.5 2.1 2 1 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 CLASP_N PF12348.8 PFH31158.1 - 0.02 14.4 0.1 5.3 6.5 0.1 3.4 2 1 2 4 4 4 0 CLASP N terminal RasGEF_N_2 PF14663.6 PFH31158.1 - 0.047 14.1 0.6 6.5 7.2 0.4 3.8 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Mo25 PF08569.11 PFH31158.1 - 0.06 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Mo25-like DUF2064 PF09837.9 PFH31159.1 - 0.051 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) CBFD_NFYB_HMF PF00808.23 PFH31160.1 - 0.001 19.3 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 PFH31160.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Sas10_Utp3 PF04000.15 PFH31161.1 - 9e-10 39.0 0.1 1.5e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF1491 PF07372.12 PFH31161.1 - 0.077 13.4 0.3 0.13 12.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) DUF1449 PF07290.11 PFH31162.1 - 0.022 14.4 2.6 0.032 13.8 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) MBOAT PF03062.19 PFH31163.1 - 3.7e-21 75.9 37.7 1.1e-13 51.3 14.1 4.2 4 0 0 4 4 4 3 MBOAT, membrane-bound O-acyltransferase family PhoD PF09423.10 PFH31165.1 - 4.4e-11 42.4 1.1 5e-10 38.9 1.1 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase zf-HIT PF04438.16 PFH31168.1 - 8.3e-06 25.6 14.3 8.3e-06 25.6 14.3 2.1 1 1 1 2 2 2 1 HIT zinc finger SOG2 PF10428.9 PFH31168.1 - 0.0065 15.7 0.2 0.0065 15.7 0.2 2.6 2 1 0 2 2 2 1 RAM signalling pathway protein PrmA PF06325.13 PFH31169.1 - 1.9e-06 27.5 0.1 3.1e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PFH31169.1 - 5.7e-06 26.9 0.2 2.6e-05 24.9 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PFH31169.1 - 2.5e-05 24.2 0.0 7e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PFH31169.1 - 3e-05 24.6 0.1 0.001 19.7 0.2 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PFH31169.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PFH31169.1 - 0.069 12.9 0.3 0.84 9.3 0.2 2.0 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 PFH31169.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MBA1 PF07961.11 PFH31170.1 - 0.043 12.9 0.3 0.068 12.2 0.3 1.2 1 0 0 1 1 1 0 MBA1-like protein Peptidase_C13 PF01650.18 PFH31171.1 - 3.8e-35 121.7 0.0 1.8e-34 119.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase C13 family Radical_SAM PF04055.21 PFH31172.1 - 5.7e-12 46.3 0.0 9.2e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 PFH31172.1 - 0.00066 19.8 0.0 0.002 18.3 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Metallophos_2 PF12850.7 PFH31174.1 - 2.8e-18 66.6 0.1 3.6e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 PFH31174.1 - 0.045 14.3 3.3 1.2 9.6 0.9 2.2 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase Kinase-like PF14531.6 PFH31175.1 - 1.1e-30 107.0 0.0 1.5e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH31175.1 - 3.1e-07 30.0 0.0 3.8e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 PFH31175.1 - 0.16 11.9 1.1 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family tRNA_bind_3 PF17176.4 PFH31175.1 - 0.29 11.4 6.7 0.14 12.5 2.4 2.4 2 0 0 2 2 2 0 tRNA-binding domain VID27 PF08553.10 PFH31176.1 - 2.1e-54 184.9 0.0 2.8e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain E1-E2_ATPase PF00122.20 PFH31177.1 - 1.8e-41 141.7 0.0 1.8e-41 141.7 0.0 3.9 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 PFH31177.1 - 1.9e-17 64.3 3.2 3.6e-17 63.3 0.7 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PFH31177.1 - 1.3e-13 50.4 0.0 3.2e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PFH31177.1 - 0.00019 21.2 6.1 0.013 15.3 1.1 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PFH31177.1 - 0.00036 20.6 0.0 0.0031 17.6 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) HAD PF12710.7 PFH31177.1 - 0.00049 20.6 0.0 0.0013 19.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MsyB PF13984.6 PFH31178.1 - 0.1 12.9 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 MsyB protein IF-2B PF01008.17 PFH31179.1 - 7.5e-57 192.7 0.0 1.6e-56 191.6 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family Cnn_1N PF07989.11 PFH31182.1 - 0.00036 20.6 4.9 0.00036 20.6 4.9 25.4 23 3 4 27 27 27 8 Centrosomin N-terminal motif 1 APG6_N PF17675.1 PFH31182.1 - 0.0029 18.1 1.0 0.0029 18.1 1.0 27.7 18 6 11 30 30 30 5 Apg6 coiled-coil region KASH_CCD PF14662.6 PFH31182.1 - 0.0034 17.2 11.0 0.0034 17.2 11.0 20.8 17 4 3 20 20 20 7 Coiled-coil region of CCDC155 or KASH Uso1_p115_C PF04871.13 PFH31182.1 - 0.0038 17.6 5.8 0.0038 17.6 5.8 23.2 16 7 5 22 22 22 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2353 PF09789.9 PFH31182.1 - 0.0044 16.4 0.0 0.0044 16.4 0.0 15.1 8 4 6 15 15 15 2 Uncharacterized coiled-coil protein (DUF2353) Uds1 PF15456.6 PFH31182.1 - 0.0061 16.7 1.4 0.0061 16.7 1.4 20.0 13 6 3 17 17 17 4 Up-regulated During Septation ELMO_CED12 PF04727.13 PFH31184.1 - 3.2e-25 89.2 0.0 4.8e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family PSI PF01437.25 PFH31184.1 - 0.2 12.2 6.7 0.44 11.1 6.7 1.5 1 0 0 1 1 1 0 Plexin repeat Glyco_hydro_31 PF01055.26 PFH31186.1 - 5.5e-132 441.1 2.5 7.4e-132 440.7 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 PFH31186.1 - 1.6e-11 44.4 4.6 2.3e-11 43.8 0.2 3.4 4 0 0 4 4 4 1 Galactose mutarotase-like DUF5110 PF17137.4 PFH31186.1 - 0.01 16.1 0.1 0.023 14.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Actin PF00022.19 PFH31187.1 - 8e-87 291.5 0.3 9.2e-79 264.9 0.1 3.6 2 1 0 2 2 2 2 Actin DUF4611 PF15387.6 PFH31187.1 - 0.035 14.3 2.5 0.093 13.0 2.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) MreB_Mbl PF06723.13 PFH31187.1 - 0.07 11.9 0.2 0.71 8.6 0.0 2.4 3 0 0 3 3 3 0 MreB/Mbl protein FAM220 PF15487.6 PFH31187.1 - 1.6 8.3 4.0 3.5 7.2 4.0 1.5 1 0 0 1 1 1 0 FAM220 family DNA_pol_phi PF04931.13 PFH31187.1 - 2.9 5.9 7.9 4 5.4 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 PFH31187.1 - 6.1 5.0 8.2 10 4.3 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.12 PFH31187.1 - 7 4.8 5.0 10 4.3 5.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus TatD_DNase PF01026.21 PFH31188.1 - 5.4e-41 140.7 0.0 7.7e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase WD40 PF00400.32 PFH31188.1 - 4.3e-09 36.8 6.2 0.49 11.4 0.0 6.8 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH31188.1 - 0.0091 16.3 0.0 0.033 14.5 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain RMI2 PF16100.5 PFH31189.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 DEAD PF00270.29 PFH31190.1 - 1.5e-37 129.1 0.0 2.7e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH31190.1 - 2.3e-29 102.0 0.3 4.3e-28 97.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH31190.1 - 5.5e-08 33.0 0.0 9.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PFH31190.1 - 0.025 14.9 0.0 0.081 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PFH31190.1 - 0.034 14.5 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain T4SS-DNA_transf PF02534.14 PFH31190.1 - 0.21 10.3 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer GMC_oxred_C PF05199.13 PFH31192.1 - 4.2e-15 56.5 0.0 2.2e-10 41.2 0.0 2.7 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_N PF00732.19 PFH31192.1 - 1.7e-14 53.9 0.0 3.6e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.24 PFH31192.1 - 0.00047 19.9 0.4 0.0011 18.6 0.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 PFH31192.1 - 0.001 18.7 0.1 0.002 17.8 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 PFH31192.1 - 0.0021 18.2 0.1 0.0075 16.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PFH31192.1 - 0.0025 17.1 0.2 0.004 16.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PFH31192.1 - 0.0094 15.0 0.1 0.023 13.8 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 PFH31192.1 - 0.025 13.7 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 PFH31192.1 - 0.038 12.7 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GDI PF00996.18 PFH31192.1 - 0.04 12.4 0.0 0.064 11.8 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor GIDA PF01134.22 PFH31192.1 - 0.053 12.6 0.1 0.089 11.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 PFH31192.1 - 0.14 12.8 0.0 0.38 11.3 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PFH31192.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Occludin_ELL PF07303.13 PFH31193.1 - 2.5 8.9 6.1 2.8 8.7 2.5 2.5 2 0 0 2 2 2 0 Occludin homology domain Lebercilin PF15619.6 PFH31194.1 - 0.049 13.3 4.1 3.9 7.1 2.1 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Rootletin PF15035.6 PFH31195.1 - 0.64 10.0 6.4 0.46 10.5 2.8 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion PLL PF18587.1 PFH31197.1 - 0.21 11.7 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 PTX/LNS-Like (PLL) domain GMC_oxred_C PF05199.13 PFH31199.1 - 7.5e-17 62.2 0.0 1.3e-12 48.5 0.0 2.9 3 0 0 3 3 3 2 GMC oxidoreductase GMC_oxred_N PF00732.19 PFH31199.1 - 2.8e-13 49.9 0.0 2.7e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.24 PFH31199.1 - 0.0057 16.3 0.1 0.017 14.7 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase ThiF PF00899.21 PFH31199.1 - 0.18 11.1 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 ThiF family DDHD PF02862.17 PFH31199.1 - 1.5 8.9 3.9 2.7 8.1 0.0 2.7 3 0 0 3 3 3 0 DDHD domain Peptidase_M14 PF00246.24 PFH31201.1 - 1.5e-26 93.9 0.0 2.5e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 PFH31201.1 - 0.0014 17.8 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF5642 PF18702.1 PFH31201.1 - 0.27 11.0 3.1 0.6 9.8 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5642) tRNA-synt_1 PF00133.22 PFH31202.1 - 1.6e-186 621.1 0.0 2.8e-185 617.1 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PFH31202.1 - 4.2e-34 117.7 0.1 1.5e-33 115.9 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PFH31202.1 - 8.1e-14 51.2 0.1 5.8e-06 25.3 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 PFH31202.1 - 8.7e-08 31.9 0.5 3e-06 26.9 0.0 2.8 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 PFH31202.1 - 2.7e-06 27.5 6.7 7.8e-06 26.1 6.7 1.8 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 PFH31202.1 - 0.026 13.9 0.0 0.45 9.8 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 PFH31202.1 - 0.037 13.3 0.3 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) tRNA-synt_1c PF00749.21 PFH31202.1 - 0.13 11.1 0.0 0.37 9.6 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Jag_N PF14804.6 PFH31202.1 - 0.48 10.8 2.1 0.64 10.4 0.0 2.3 3 0 0 3 3 3 0 Jag N-terminus DUF4200 PF13863.6 PFH31206.1 - 4e-22 78.8 24.0 4e-22 78.8 24.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) Tic22 PF04278.12 PFH31207.1 - 0.012 15.0 0.1 13 5.1 0.0 3.1 3 0 0 3 3 3 0 Tic22-like family Glucos_trans_II PF14264.6 PFH31208.1 - 0.013 14.9 0.6 0.017 14.5 0.6 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII CheZ PF04344.13 PFH31208.1 - 0.072 13.0 3.4 0.16 11.9 0.2 2.3 2 1 0 2 2 2 0 Chemotaxis phosphatase, CheZ Syntaxin-6_N PF09177.11 PFH31208.1 - 0.1 13.2 4.7 0.072 13.7 0.9 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Laminin_II PF06009.12 PFH31208.1 - 0.19 11.8 3.1 0.79 9.7 0.3 2.6 2 1 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 PFH31208.1 - 0.31 11.1 7.3 0.059 13.4 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 PFH31208.1 - 0.98 8.7 7.6 21 4.3 7.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TipAS PF07739.13 PFH31208.1 - 2.9 8.5 8.1 3.3 8.3 0.1 2.9 3 1 0 3 3 3 0 TipAS antibiotic-recognition domain Atg14 PF10186.9 PFH31208.1 - 3 6.8 7.2 0.94 8.5 2.9 2.0 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0542 PF15086.6 PFH31208.1 - 6.6 6.7 5.4 0.87 9.6 0.4 2.2 2 1 1 3 3 3 0 Uncharacterised protein family UPF0542 AP2 PF00847.20 PFH31210.1 - 1.5e-10 41.1 0.0 2.6e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 AP2 domain ELMO_CED12 PF04727.13 PFH31213.1 - 4.3e-34 118.2 0.7 7e-34 117.5 0.7 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family SelP_N PF04592.14 PFH31215.1 - 0.0064 15.9 14.1 0.0087 15.5 14.1 1.1 1 0 0 1 1 1 1 Selenoprotein P, N terminal region DUF732 PF05305.14 PFH31215.1 - 0.23 11.9 1.4 0.35 11.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF732) DUF732 PF05305.14 PFH31216.1 - 0.07 13.5 0.4 0.11 12.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF732) NTP_transf_2 PF01909.23 PFH31217.1 - 2.2e-05 24.7 0.0 3.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 PFH31217.1 - 0.0049 17.0 0.1 0.01 16.0 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 PFH31217.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase MdcG PF10620.9 PFH31217.1 - 0.087 12.6 1.5 0.22 11.3 1.5 1.6 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG Nrap_D2 PF17403.2 PFH31217.1 - 0.14 11.9 0.0 6.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Nrap protein PAP/OAS-like domain PFK PF00365.20 PFH31219.1 - 1.3e-45 155.9 0.0 2.9e-27 95.7 0.0 2.6 3 0 0 3 3 3 2 Phosphofructokinase Hist_deacetyl PF00850.19 PFH31220.1 - 1e-77 261.6 0.0 1.3e-43 149.6 0.0 2.7 1 1 1 2 2 2 2 Histone deacetylase domain IPK PF03770.16 PFH31220.1 - 3e-35 121.9 0.0 6.5e-35 120.8 0.0 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase Pkinase PF00069.25 PFH31221.1 - 6.8e-40 137.1 0.0 1e-39 136.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31221.1 - 1.4e-19 70.4 0.0 2.9e-19 69.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PFH31221.1 - 0.00019 20.3 0.0 0.00027 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PFH31221.1 - 0.00044 19.7 0.0 0.00092 18.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF3712 PF12505.8 PFH31222.1 - 5.8e-39 133.2 0.0 3.3e-14 53.2 0.0 9.3 9 0 0 9 9 9 7 Protein of unknown function (DUF3712) LEA_2 PF03168.13 PFH31222.1 - 2.3e-07 31.3 3.7 1.5 9.4 0.0 8.6 10 0 0 10 10 10 2 Late embryogenesis abundant protein DUF4426 PF14467.6 PFH31222.1 - 0.16 11.9 0.0 13 5.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4426) Pkinase PF00069.25 PFH31223.1 - 2.1e-66 224.0 0.0 2.7e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31223.1 - 2.1e-30 105.9 0.0 5.8e-30 104.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PFH31223.1 - 1.3e-07 31.0 0.0 1.3e-07 31.0 0.0 1.6 1 1 1 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 PFH31223.1 - 0.017 14.8 0.1 0.12 12.0 0.1 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 PFH31223.1 - 0.026 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 PFH31223.1 - 0.036 13.4 0.1 0.35 10.2 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PFH31223.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 Kinase-like T3SS_needle_E PF08988.10 PFH31223.1 - 0.075 13.2 1.3 0.75 10.0 0.6 2.3 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle APH PF01636.23 PFH31223.1 - 0.21 11.5 1.2 0.31 10.9 0.1 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Tape_meas_lam_C PF09718.10 PFH31224.1 - 0.013 15.6 0.8 0.042 14.0 0.8 1.9 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF4404 PF14357.6 PFH31224.1 - 0.13 12.9 0.0 0.29 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) WD40 PF00400.32 PFH31226.1 - 2.1e-14 53.7 17.8 0.00028 21.6 0.2 8.4 8 1 0 8 8 8 4 WD domain, G-beta repeat PQQ_3 PF13570.6 PFH31226.1 - 0.27 11.8 3.8 1.2 9.7 0.4 3.8 3 0 0 3 3 3 0 PQQ-like domain Nup160 PF11715.8 PFH31226.1 - 0.31 9.6 0.5 20 3.6 0.0 2.8 3 1 1 4 4 4 0 Nucleoporin Nup120/160 SNO PF01174.19 PFH31227.1 - 6.1e-43 146.9 0.0 3.2e-41 141.2 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family DJ-1_PfpI PF01965.24 PFH31227.1 - 2.5e-07 30.6 0.0 7.8e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 DJ-1/PfpI family GATase_3 PF07685.14 PFH31227.1 - 1e-06 28.5 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 PFH31227.1 - 0.011 15.5 0.2 0.038 13.7 0.2 1.8 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 PFH31227.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 ThiJ_like PF17124.5 PFH31227.1 - 0.035 13.8 0.0 0.074 12.7 0.0 1.5 2 0 0 2 2 2 0 ThiJ/PfpI family-like GATase_5 PF13507.6 PFH31227.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 PFH31227.1 - 0.18 11.5 0.1 2.3 7.9 0.1 2.2 1 1 0 1 1 1 0 Peptidase C26 Aminotran_4 PF01063.19 PFH31228.1 - 8.9e-20 71.5 0.1 5.9e-17 62.3 0.0 2.3 2 0 0 2 2 2 2 Amino-transferase class IV RNase_HII PF01351.18 PFH31229.1 - 3.9e-48 163.9 0.4 4.6e-44 150.6 0.1 2.5 2 1 1 3 3 3 2 Ribonuclease HII Presenilin PF01080.17 PFH31229.1 - 0.088 11.6 0.5 0.12 11.1 0.5 1.2 1 0 0 1 1 1 0 Presenilin DUF1874 PF08960.10 PFH31229.1 - 0.1 12.7 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) RNA_pol_Rpc4 PF05132.14 PFH31229.1 - 0.23 11.9 5.6 0.54 10.7 5.6 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Coilin_N PF15862.5 PFH31229.1 - 1.2 9.0 7.0 3.3 7.5 7.0 1.8 1 0 0 1 1 1 0 Coilin N-terminus zf-RING_2 PF13639.6 PFH31230.1 - 1.5e-13 50.9 7.2 3e-13 49.9 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PFH31230.1 - 1.9e-08 34.5 4.9 3.7e-08 33.5 4.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PFH31230.1 - 4.2e-07 29.7 4.1 4.2e-07 29.7 4.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH31230.1 - 1.3e-06 28.2 3.1 2.7e-06 27.3 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PFH31230.1 - 4.1e-06 26.5 7.1 8.6e-06 25.5 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PFH31230.1 - 6.2e-06 25.8 2.8 6.2e-06 25.8 2.8 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 PFH31230.1 - 6.5e-06 26.1 1.6 1.3e-05 25.2 1.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 PFH31230.1 - 1.7e-05 24.8 5.3 3.1e-05 24.0 5.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.6 PFH31230.1 - 0.00015 21.5 5.3 0.00032 20.4 5.3 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 PFH31230.1 - 0.00016 21.8 4.3 0.00057 20.0 4.3 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 PFH31230.1 - 0.00065 19.5 5.6 0.00065 19.5 5.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PFH31230.1 - 0.0011 18.8 8.1 0.022 14.6 7.4 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PFH31230.1 - 0.0012 18.8 0.4 0.0012 18.8 0.4 2.5 2 1 1 3 3 3 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 PFH31230.1 - 0.0032 17.0 4.4 0.0062 16.1 4.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Baculo_RING PF05883.11 PFH31230.1 - 0.053 13.5 0.4 0.1 12.6 0.4 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Prok-RING_1 PF14446.6 PFH31230.1 - 0.088 12.8 4.8 0.27 11.2 1.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF5318 PF17249.2 PFH31230.1 - 0.2 11.4 1.6 0.3 10.9 0.8 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5318) zf-P11 PF03854.14 PFH31230.1 - 0.44 10.2 5.3 4.3 7.1 5.0 2.3 1 1 1 2 2 2 0 P-11 zinc finger Gcd10p PF04189.13 PFH31231.1 - 9.8e-43 146.4 0.0 1.2e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family Auxin_inducible PF02519.14 PFH31231.1 - 0.0071 16.5 0.1 0.029 14.5 0.1 2.2 1 0 0 1 1 1 1 Auxin responsive protein DUF3886 PF13025.6 PFH31233.1 - 3.1 8.1 6.3 0.32 11.2 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) VPS9 PF02204.18 PFH31234.1 - 4.4e-07 30.1 0.0 7.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PP2C PF00481.21 PFH31236.1 - 5e-44 150.9 0.0 9.2e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PFH31236.1 - 0.003 17.2 0.3 0.021 14.5 0.1 2.4 1 1 1 2 2 2 1 Protein phosphatase 2C GRP PF07172.11 PFH31237.1 - 0.00018 22.1 3.5 0.00024 21.7 3.5 1.2 1 0 0 1 1 1 1 Glycine rich protein family DUF4680 PF15730.5 PFH31239.1 - 0.0049 17.2 4.1 0.015 15.7 1.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4680) Aldo_ket_red PF00248.21 PFH31240.1 - 3.9e-26 91.9 0.0 1.5e-23 83.5 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family HAGH_C PF16123.5 PFH31241.1 - 2.5e-27 95.2 0.7 4e-27 94.5 0.7 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 PFH31241.1 - 4.3e-07 30.2 0.7 2.3e-06 27.8 0.7 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PFH31241.1 - 0.0058 16.2 0.0 0.01 15.3 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HMG_box PF00505.19 PFH31246.1 - 1e-06 29.0 3.4 3.8e-06 27.2 3.5 3.5 3 0 0 3 3 3 2 HMG (high mobility group) box SET PF00856.28 PFH31246.1 - 0.54 10.6 9.4 1.3 9.4 0.3 3.8 1 1 1 2 2 2 0 SET domain DUF2749 PF10907.8 PFH31247.1 - 0.67 10.2 0.1 0.67 10.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) ATP-synt_D PF01813.17 PFH31248.1 - 4.6e-61 206.1 0.5 5.3e-61 205.9 0.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit D FlgN PF05130.12 PFH31248.1 - 0.11 13.0 1.5 0.37 11.3 0.1 2.2 2 0 0 2 2 2 0 FlgN protein TFIIF_beta PF02270.15 PFH31249.1 - 0.0027 17.8 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 PFH31249.1 - 0.12 13.1 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus DER1 PF04511.15 PFH31250.1 - 4e-14 53.0 0.0 5.8e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Der1-like family LRV PF01816.17 PFH31250.1 - 0.41 11.2 5.0 34 5.1 0.0 4.5 4 0 0 4 4 4 0 Leucine rich repeat variant ADK PF00406.22 PFH31252.1 - 1.4e-28 99.9 0.0 2.2e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PFH31252.1 - 4.2e-20 72.6 2.3 4.8e-20 72.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PFH31252.1 - 9.9e-11 42.3 0.7 3.4e-10 40.6 0.0 2.3 2 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 PFH31252.1 - 8e-07 29.3 0.0 3.8e-06 27.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 PFH31252.1 - 0.001 19.4 0.4 0.0025 18.0 0.0 1.9 3 0 0 3 3 3 1 AAA domain Cytidylate_kin PF02224.18 PFH31252.1 - 0.011 15.5 0.0 0.011 15.5 0.0 2.6 2 1 1 4 4 4 0 Cytidylate kinase KTI12 PF08433.10 PFH31252.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Med8 PF10232.9 PFH31252.1 - 0.11 12.1 1.0 0.27 10.8 1.0 1.7 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 CENP-Q PF13094.6 PFH31252.1 - 1.1 9.5 5.9 2.5 8.3 5.9 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CTP_transf_1 PF01148.20 PFH31253.1 - 4.5e-66 223.3 9.1 4.8e-65 220.0 9.1 2.3 1 1 0 1 1 1 1 Cytidylyltransferase family DUF1189 PF06691.11 PFH31253.1 - 0.17 11.5 0.1 0.39 10.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Isochorismatase PF00857.20 PFH31254.1 - 6.6e-25 88.3 0.2 8.8e-20 71.6 0.4 2.3 2 0 0 2 2 2 2 Isochorismatase family MDMPI_N PF11716.8 PFH31254.1 - 0.53 11.0 8.2 5.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain PCB_OB PF17092.5 PFH31259.1 - 0.021 15.6 0.9 0.021 15.6 0.9 1.9 1 1 1 2 2 2 0 Penicillin-binding protein OB-like domain ICA69 PF04629.14 PFH31259.1 - 0.42 10.9 8.8 0.55 10.5 8.8 1.3 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain HGTP_anticodon2 PF12745.7 PFH31259.1 - 6.5 6.2 19.6 9.1 5.7 19.6 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Cofilin_ADF PF00241.20 PFH31261.1 - 9.5e-12 44.8 0.0 4.7e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF5312 PF17239.2 PFH31262.1 - 0.082 11.2 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5312) VEGFR-2_TMD PF17988.1 PFH31263.1 - 0.4 10.2 1.7 0.72 9.3 1.7 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain DUF1635 PF07795.11 PFH31264.1 - 0.11 12.3 19.4 0.24 11.2 19.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Miga PF10265.9 PFH31264.1 - 1.7 7.5 15.2 3.3 6.6 15.2 1.4 1 0 0 1 1 1 0 Mitoguardin DUF4718 PF15842.5 PFH31264.1 - 3.2 7.5 11.9 8 6.2 11.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Milton PF12448.8 PFH31267.1 - 0.019 15.1 1.3 0.022 14.9 1.3 1.0 1 0 0 1 1 1 0 Kinesin associated protein RmuC PF02646.16 PFH31269.1 - 0.047 12.8 0.2 0.1 11.7 0.2 1.5 1 0 0 1 1 1 0 RmuC family Kinesin_assoc PF16183.5 PFH31269.1 - 0.17 12.0 0.1 0.25 11.5 0.1 1.2 1 0 0 1 1 1 0 Kinesin-associated NUDIX PF00293.28 PFH31270.1 - 5.3e-14 52.4 0.0 9.5e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain AAA_2 PF07724.14 PFH31271.1 - 2.9e-42 144.7 3.5 4.7e-40 137.5 0.2 3.9 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 PFH31271.1 - 1.1e-25 90.5 0.0 9.7e-13 48.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_9 PF17871.1 PFH31271.1 - 6.1e-25 87.1 11.4 6.1e-25 87.1 11.4 2.4 2 1 0 2 2 1 1 AAA lid domain ClpB_D2-small PF10431.9 PFH31271.1 - 8.4e-18 64.2 0.1 7.9e-17 61.1 0.0 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 PFH31271.1 - 4.7e-17 62.3 1.5 7.3e-11 42.2 0.0 3.5 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PFH31271.1 - 8.7e-12 45.5 0.1 0.0002 21.6 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 PFH31271.1 - 4.6e-11 43.4 4.1 0.00014 22.3 0.0 4.8 5 1 0 5 5 3 2 AAA ATPase domain AAA_7 PF12775.7 PFH31271.1 - 1.8e-08 34.1 0.0 0.0058 16.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 PFH31271.1 - 2.4e-08 33.6 0.4 7.4e-05 22.2 0.0 4.1 3 1 0 3 3 3 1 Bacterial TniB protein Sigma54_activat PF00158.26 PFH31271.1 - 3.2e-08 33.4 0.7 5.5e-06 26.2 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 PFH31271.1 - 2.1e-07 30.9 0.1 0.0092 15.7 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 PFH31271.1 - 3.9e-07 30.2 0.0 0.11 12.6 0.0 4.0 4 0 0 4 4 4 2 AAA domain Clp_N PF02861.20 PFH31271.1 - 6.8e-07 29.3 0.7 0.015 15.4 0.2 3.0 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component RuvB_N PF05496.12 PFH31271.1 - 1.3e-05 25.0 3.2 0.013 15.2 0.0 4.5 4 1 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 PFH31271.1 - 1.5e-05 25.5 3.5 0.04 14.5 0.0 3.7 3 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 PFH31271.1 - 3e-05 24.4 0.0 0.38 11.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase ResIII PF04851.15 PFH31271.1 - 4.8e-05 23.4 1.3 0.4 10.7 0.0 4.0 3 1 1 4 4 4 2 Type III restriction enzyme, res subunit AAA_33 PF13671.6 PFH31271.1 - 6.9e-05 23.0 0.0 0.27 11.4 0.0 3.2 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 PFH31271.1 - 7e-05 22.8 0.0 0.13 12.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain Zeta_toxin PF06414.12 PFH31271.1 - 0.0001 21.6 0.1 0.011 15.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 PFH31271.1 - 0.00023 20.6 1.7 0.55 9.6 0.1 3.3 2 2 0 2 2 2 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 PFH31271.1 - 0.00039 20.4 0.1 0.66 10.0 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 PFH31271.1 - 0.00047 20.4 0.0 0.43 10.8 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_3 PF07726.11 PFH31271.1 - 0.0046 16.8 0.1 3.9 7.3 0.0 3.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PFH31271.1 - 0.0057 16.6 0.0 1.8 8.5 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase ATPase_2 PF01637.18 PFH31271.1 - 0.0065 16.4 11.2 5 7.0 0.1 5.1 4 2 0 5 5 3 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 PFH31271.1 - 0.0078 15.3 0.0 0.021 13.9 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.6 PFH31271.1 - 0.0095 16.2 4.9 1.8 8.8 0.0 3.8 3 1 1 4 4 4 1 AAA domain AAA_19 PF13245.6 PFH31271.1 - 0.018 15.4 0.5 2.6 8.4 1.3 3.4 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PFH31271.1 - 0.018 14.6 0.6 6.7 6.2 0.1 2.9 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 PFH31271.1 - 0.024 13.8 0.0 0.66 9.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 PFH31271.1 - 0.028 14.3 0.5 10 6.0 0.0 4.0 5 0 0 5 5 4 0 NTPase DNA_pol3_delta2 PF13177.6 PFH31271.1 - 0.032 14.0 0.0 0.87 9.4 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_29 PF13555.6 PFH31271.1 - 0.034 13.9 0.2 7.2 6.4 0.0 2.9 3 0 0 3 3 2 0 P-loop containing region of AAA domain CBFD_NFYB_HMF PF00808.23 PFH31271.1 - 0.045 14.1 3.1 0.092 13.0 0.3 3.0 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ABC_tran PF00005.27 PFH31271.1 - 0.18 12.3 6.1 0.52 10.8 0.0 3.4 4 1 0 4 4 3 0 ABC transporter DUF87 PF01935.17 PFH31271.1 - 2.2 8.3 0.0 2.2 8.3 0.0 4.0 5 0 0 5 5 4 0 Helicase HerA, central domain ACDC PF14733.6 PFH31272.1 - 1.5e-15 57.3 0.3 3.5e-15 56.1 0.0 1.7 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.20 PFH31272.1 - 2.4e-05 24.5 5.4 0.00011 22.4 5.4 2.0 2 0 0 2 2 2 1 AP2 domain AP2 PF00847.20 PFH31273.1 - 4.6e-23 81.2 5.7 2.6e-10 40.4 0.4 3.5 3 0 0 3 3 3 3 AP2 domain ATP-sulfurylase PF01747.17 PFH31274.1 - 1.3e-85 286.2 0.0 1.8e-85 285.7 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 PFH31274.1 - 2.2e-57 193.4 0.0 4e-57 192.5 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 PFH31274.1 - 1.4e-25 89.8 0.0 8.7e-16 58.0 0.0 2.3 2 0 0 2 2 2 2 PUA-like domain AAA_33 PF13671.6 PFH31274.1 - 1.6e-05 25.1 0.0 2.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 PFH31274.1 - 6.1e-05 22.6 0.0 9.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 PFH31274.1 - 0.0017 18.6 0.0 0.0036 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PFH31274.1 - 0.0028 18.2 0.0 0.0058 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PFH31274.1 - 0.019 15.3 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 PFH31274.1 - 0.088 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 PFH31274.1 - 0.1 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 PFH31274.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 PFH31274.1 - 0.15 11.8 0.0 0.97 9.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain CvfB_WH PF17783.1 PFH31275.1 - 0.033 14.0 0.2 62 3.5 0.0 3.1 3 0 0 3 3 3 0 CvfB-like winged helix domain MAGI_u5 PF16666.5 PFH31275.1 - 2.6 8.2 27.8 0.5 10.5 1.3 4.0 1 1 3 4 4 4 0 Unstructured region on MAGI HMG14_17 PF01101.18 PFH31275.1 - 3.7 8.6 6.0 41 5.2 0.2 3.1 3 0 0 3 3 3 0 HMG14 and HMG17 DUF883 PF05957.13 PFH31276.1 - 0.01 16.4 7.2 0.13 12.9 1.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 PFH31276.1 - 0.022 15.3 6.6 0.53 10.8 0.4 2.1 1 1 1 2 2 2 0 YtxH-like protein Synuclein PF01387.17 PFH31276.1 - 0.027 14.7 5.1 0.039 14.2 5.1 1.3 1 0 0 1 1 1 0 Synuclein ApoLp-III PF07464.11 PFH31276.1 - 0.032 14.3 3.3 0.28 11.3 0.6 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Use1 PF09753.9 PFH31276.1 - 1 9.0 4.1 1.1 9.0 4.1 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Alanine_zipper PF11839.8 PFH31276.1 - 1.5 9.2 19.1 1.4 9.3 5.9 2.2 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein ATP-synt_B PF00430.18 PFH31276.1 - 5.5 7.1 11.3 2.3 8.3 1.6 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) YtxH PF12732.7 PFH31277.1 - 1.1e-08 35.5 73.8 0.014 15.9 3.8 8.7 3 2 2 6 6 6 4 YtxH-like protein Apolipoprotein PF01442.18 PFH31277.1 - 1.8e-07 31.2 38.4 0.00044 20.2 3.8 4.5 2 1 3 5 5 5 4 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 PFH31277.1 - 6.3e-05 23.5 60.0 0.2 12.2 3.8 8.1 2 1 6 8 8 8 7 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 PFH31277.1 - 0.00096 19.3 24.7 0.027 14.6 0.4 6.1 2 2 3 6 6 6 4 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 PFH31279.1 - 0.0052 17.4 13.7 0.063 13.9 1.5 2.7 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 PFH31279.1 - 0.011 15.8 0.7 0.014 15.5 0.7 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 PFH31279.1 - 0.03 14.9 17.7 6.2 7.4 3.0 3.1 1 1 1 2 2 2 0 YtxH-like protein Entericidin PF08085.11 PFH31279.1 - 0.046 13.8 4.8 1.2 9.3 0.1 4.2 4 0 0 4 4 4 0 Entericidin EcnA/B family Ribosomal_60s PF00428.19 PFH31280.1 - 1.5 9.5 10.8 0.045 14.3 0.9 3.3 2 1 1 3 3 3 0 60s Acidic ribosomal protein Mito_carr PF00153.27 PFH31281.1 - 2.7e-09 36.8 0.0 0.00053 19.9 0.0 2.7 2 0 0 2 2 2 2 Mitochondrial carrier protein ER_lumen_recept PF00810.18 PFH31282.1 - 2.5e-46 158.1 11.1 2.5e-46 158.1 11.1 1.7 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 PFH31282.1 - 0.055 13.2 12.9 0.12 12.2 0.3 3.9 4 1 1 5 5 5 0 PQ loop repeat PP2C PF00481.21 PFH31283.1 - 1.6e-38 132.8 0.0 2.4e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PFH31283.1 - 0.028 14.3 0.0 0.073 13.0 0.0 1.7 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) IMP2_N PF18590.1 PFH31284.1 - 1.1e-27 96.4 0.2 1.4e-27 96.0 0.2 1.2 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 PFH31284.1 - 4.7e-22 77.6 0.3 7.5e-22 77.0 0.3 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) C-terminal domain RAMP4 PF06624.12 PFH31285.1 - 1.3e-22 79.6 0.0 1.4e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 F-box-like PF12937.7 PFH31287.1 - 0.0044 16.9 0.5 0.014 15.3 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PFH31287.1 - 0.067 13.1 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 F-box domain TPR_1 PF00515.28 PFH31288.1 - 4.9e-09 35.6 9.0 0.0073 16.1 0.1 4.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 PFH31288.1 - 6e-06 26.0 14.6 0.0092 16.0 0.6 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 PFH31288.1 - 0.0017 18.0 0.2 0.55 10.0 0.0 2.5 2 0 0 2 2 2 2 TPR repeat DUF383 PF04063.14 PFH31288.1 - 0.029 14.0 0.0 0.84 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF383) TPR_19 PF14559.6 PFH31288.1 - 0.22 12.1 7.1 4.7 7.8 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RUN PF02759.19 PFH31288.1 - 0.25 11.3 1.0 1.4 8.9 0.3 2.5 2 0 0 2 2 2 0 RUN domain LEDGF PF11467.8 PFH31288.1 - 0.44 10.2 3.8 6.3 6.4 0.1 2.5 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) TPR_12 PF13424.6 PFH31288.1 - 9.5 6.6 23.0 0.054 13.8 1.9 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 PFH31290.1 - 6.4e-08 32.6 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sec23_trunk PF04811.15 PFH31291.1 - 3.6e-38 131.5 0.0 6.5e-31 107.8 0.0 3.2 2 1 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 PFH31291.1 - 3.4e-24 84.6 0.0 8e-24 83.4 0.0 1.7 1 1 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 PFH31291.1 - 2.7e-16 59.3 4.4 4.4e-16 58.6 4.4 1.3 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 PFH31291.1 - 1e-15 58.2 0.0 1.8e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 PFH31291.1 - 4.8e-05 23.2 0.3 0.00017 21.4 0.0 2.1 3 0 0 3 3 3 1 Gelsolin repeat Vps36-NZF-N PF16988.5 PFH31291.1 - 0.14 11.5 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain SufE PF02657.15 PFH31292.1 - 3.3e-28 98.0 0.0 5.7e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain tRNA-synt_1 PF00133.22 PFH31293.1 - 6.5e-96 321.9 0.0 1.8e-22 79.4 0.0 8.2 8 1 0 8 8 8 7 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PFH31293.1 - 3.8e-20 72.4 0.0 6.4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PFH31293.1 - 9.5e-11 41.1 0.0 2.6e-06 26.5 0.0 3.9 4 0 0 4 4 4 2 tRNA synthetases class I (M) SPRY PF00622.28 PFH31294.1 - 0.00046 20.3 0.1 0.008 16.3 0.0 2.4 2 0 0 2 2 2 1 SPRY domain SNF2_N PF00176.23 PFH31296.1 - 2.9e-27 95.3 0.0 4.4e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PFH31296.1 - 1.4e-12 48.0 0.0 3.4e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH31296.1 - 3.3e-05 24.0 0.0 6.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PFH31296.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SUB1_ProdP9 PF18213.1 PFH31297.1 - 0.00056 19.7 0.0 0.00076 19.3 0.0 1.3 1 0 0 1 1 1 1 SUB1 protease Prodomain ProdP9 DUF2561 PF10812.8 PFH31297.1 - 0.048 13.7 0.5 0.073 13.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) RXLR_WY PF18634.1 PFH31297.1 - 0.076 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain HECT PF00632.25 PFH31298.1 - 6.8e-78 262.3 0.0 8.5e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TTL PF03133.15 PFH31299.1 - 4.2e-85 285.4 0.2 5.8e-85 285.0 0.2 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PFH31299.1 - 3.2e-13 49.5 0.0 1.1e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PFH31299.1 - 5.9e-05 22.5 0.0 0.0029 16.9 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp DHHC PF01529.20 PFH31300.1 - 0.84 9.7 4.5 0.47 10.5 1.1 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase MIG-14_Wnt-bd PF06664.12 PFH31300.1 - 2 7.6 8.2 0.55 9.4 2.5 1.9 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion Wzz PF02706.15 PFH31300.1 - 5.6 7.3 6.1 43 4.5 1.7 2.7 2 0 0 2 2 2 0 Chain length determinant protein DUF4231 PF14015.6 PFH31300.1 - 6.3 7.3 15.9 6.9 7.2 5.3 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) PALP PF00291.25 PFH31301.1 - 1.1e-37 130.1 0.0 1e-23 84.2 0.0 2.3 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Kdo PF06293.14 PFH31302.1 - 6.2e-09 35.5 0.0 0.0001 21.7 0.0 2.6 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 PFH31302.1 - 0.0019 17.6 0.0 0.019 14.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 PFH31302.1 - 0.012 15.3 0.0 0.9 9.1 0.0 2.5 2 0 0 2 2 2 0 RIO1 family STELLO PF03385.17 PFH31302.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 STELLO glycosyltransferases EcKinase PF02958.20 PFH31302.1 - 0.18 11.1 0.1 0.51 9.6 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase APH PF01636.23 PFH31302.1 - 0.44 10.4 16.1 0.41 10.5 7.1 3.8 3 1 0 3 3 3 0 Phosphotransferase enzyme family CASP_C PF08172.12 PFH31303.1 - 2.8e-13 49.8 12.0 2.8e-09 36.7 2.2 5.0 3 1 0 4 4 4 2 CASP C terminal Ntox1 PF15500.6 PFH31303.1 - 0.07 13.5 0.1 0.07 13.5 0.1 4.3 3 2 1 4 4 4 0 Putative RNase-like toxin, toxin_1 WD40_alt PF14077.6 PFH31303.1 - 0.31 10.9 3.7 0.95 9.4 0.4 3.2 3 0 0 3 3 3 0 Alternative WD40 repeat motif GDA1_CD39 PF01150.17 PFH31305.1 - 7.2e-16 57.9 0.0 1.9e-14 53.2 0.0 2.7 3 1 0 3 3 3 2 GDA1/CD39 (nucleoside phosphatase) family Myosin_head PF00063.21 PFH31306.1 - 4e-196 653.3 0.0 1.9e-194 647.7 0.0 2.4 1 1 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 PFH31306.1 - 2.5e-08 33.0 38.3 0.045 13.6 1.9 6.8 6 0 0 6 6 6 5 IQ calmodulin-binding motif WD40 PF00400.32 PFH31306.1 - 2.2e-05 25.1 5.9 0.5 11.3 0.3 5.4 6 0 0 6 6 4 2 WD domain, G-beta repeat AAA_22 PF13401.6 PFH31306.1 - 0.00041 20.6 1.2 0.3 11.4 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 PFH31306.1 - 0.0011 19.0 0.1 0.012 15.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ANAPC4_WD40 PF12894.7 PFH31306.1 - 0.0019 18.4 0.0 4.3 7.7 0.0 4.3 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_33 PF13671.6 PFH31306.1 - 0.0084 16.3 0.4 0.15 12.2 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 PFH31306.1 - 0.017 14.7 0.0 0.79 9.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 PFH31306.1 - 0.017 15.1 0.0 4.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 PFH31306.1 - 0.026 14.5 0.1 2.3 8.1 0.0 2.8 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 PFH31306.1 - 0.029 14.6 0.0 2.3 8.4 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TPR_MLP1_2 PF07926.12 PFH31306.1 - 0.064 13.3 36.6 0.036 14.1 10.0 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein RNA_helicase PF00910.22 PFH31306.1 - 0.069 13.5 0.0 7.8 6.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 PFH31306.1 - 0.074 13.4 0.0 0.074 13.4 0.0 5.2 5 2 0 5 5 3 0 AAA ATPase domain AAA PF00004.29 PFH31306.1 - 0.076 13.4 0.0 2.2 8.7 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 PFH31306.1 - 0.1 11.9 1.4 14 5.0 0.1 3.2 4 0 0 4 4 4 0 KaiC R2K_2 PF18299.1 PFH31306.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 RsgA_GTPase PF03193.16 PFH31306.1 - 0.19 11.6 0.5 21 5.0 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase CorA PF01544.18 PFH31306.1 - 0.38 10.0 8.0 0.71 9.1 8.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.10 PFH31306.1 - 1.4 9.1 10.9 1.6 8.9 8.2 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ABC_tran PF00005.27 PFH31306.1 - 1.9 9.0 6.3 8.3 6.9 0.0 3.9 4 2 0 4 4 3 0 ABC transporter DUF4200 PF13863.6 PFH31306.1 - 2.5 8.5 29.8 0.55 10.7 13.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.7 PFH31306.1 - 3.5 7.8 28.3 0.2 11.8 8.2 2.5 2 0 0 2 2 2 0 Tropomyosin like Fez1 PF06818.15 PFH31306.1 - 8.5 6.8 32.3 12 6.3 29.9 2.3 1 1 1 2 2 2 0 Fez1 Rdx PF10262.9 PFH31307.1 - 0.044 14.0 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Rdx family DHHC PF01529.20 PFH31308.1 - 7e-37 126.5 12.1 7e-37 126.5 12.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4820 PF16091.5 PFH31309.1 - 0.0083 15.5 1.5 0.019 14.3 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) Draxin PF15550.6 PFH31309.1 - 0.16 11.8 7.3 0.024 14.5 1.7 2.0 2 0 0 2 2 2 0 Draxin Lustrin_cystein PF14625.6 PFH31309.1 - 0.25 11.7 4.1 0.34 11.3 2.4 2.0 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain CPSF100_C PF13299.6 PFH31309.1 - 0.44 10.7 7.1 1.1 9.4 5.9 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_S49_N PF08496.10 PFH31309.1 - 5.3 7.1 9.7 10 6.2 9.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ORC_WH_C PF18137.1 PFH31309.1 - 6.3 6.9 10.8 1.6 8.8 7.2 1.8 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal CMS1 PF14617.6 PFH31309.1 - 7.6 5.8 8.7 13 5.1 8.7 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit G6PD_C PF02781.16 PFH31310.1 - 7.6e-105 350.3 0.0 1e-104 349.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 PFH31310.1 - 4.5e-48 164.2 0.0 1e-47 163.0 0.0 1.6 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Glucosamine_iso PF01182.20 PFH31310.1 - 3.3e-39 135.1 0.0 1e-37 130.2 0.0 2.2 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase BRX PF08381.11 PFH31311.1 - 0.23 10.8 0.0 0.4 10.1 0.0 1.3 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 MFS_1 PF07690.16 PFH31313.1 - 5.5e-37 127.5 35.4 1.4e-22 80.2 14.8 3.4 3 0 0 3 3 3 3 Major Facilitator Superfamily Tctex-1 PF03645.13 PFH31314.1 - 2.6e-24 85.4 0.0 3.4e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family ubiquitin PF00240.23 PFH31315.1 - 5e-06 26.2 0.0 8.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PFH31315.1 - 0.0029 17.4 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Sulphotransf PF09037.10 PFH31315.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Stf0 sulphotransferase RNF111_N PF15303.6 PFH31316.1 - 1.8 8.2 8.6 0.16 11.7 3.3 2.0 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus AT_hook PF02178.19 PFH31319.1 - 2.8e-05 23.5 88.1 0.18 11.8 5.3 8.4 8 0 0 8 8 8 6 AT hook motif Usp PF00582.26 PFH31319.1 - 0.74 10.3 2.4 2.4 8.6 1.3 2.2 2 0 0 2 2 2 0 Universal stress protein family Orn_Arg_deC_N PF02784.16 PFH31320.1 - 1.3e-28 100.0 0.0 1.8e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PFH31320.1 - 5.2e-22 77.9 0.0 7.4e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Mac PF12464.8 PFH31320.1 - 0.014 15.6 1.4 4 7.7 0.1 3.5 3 0 0 3 3 3 0 Maltose acetyltransferase WD40 PF00400.32 PFH31321.1 - 0.11 13.4 6.6 8.6 7.4 0.4 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat ASH PF15780.5 PFH31323.1 - 2.2e-12 47.0 0.7 9.1e-08 32.2 0.2 2.9 3 0 0 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 PFH31323.1 - 1e-09 38.5 0.3 7.5e-08 32.5 0.0 3.0 2 1 1 3 3 3 1 Flagellar-associated PapD-like TMEM131_like PF12371.8 PFH31323.1 - 2.8e-06 27.5 1.1 0.0041 17.3 0.3 2.7 2 0 0 2 2 2 2 Transmembrane protein 131-like Motile_Sperm PF00635.26 PFH31323.1 - 6.7e-05 22.7 0.2 0.43 10.4 0.0 2.6 3 0 0 3 3 3 2 MSP (Major sperm protein) domain CART PF06373.11 PFH31323.1 - 0.1 12.8 1.3 0.34 11.1 1.3 1.8 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) UQ_con PF00179.26 PFH31326.1 - 2.1e-14 53.3 0.0 3.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4116 PF13475.6 PFH31326.1 - 0.15 11.8 0.1 4.6 7.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) E1-E2_ATPase PF00122.20 PFH31327.1 - 8.5e-47 159.0 0.2 8.5e-47 159.0 0.2 2.2 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 PFH31327.1 - 1.9e-32 112.4 0.2 1.7e-31 109.3 0.0 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 PFH31327.1 - 3.4e-21 76.5 5.4 1.9e-18 67.5 1.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PFH31327.1 - 7.2e-20 70.5 0.1 1.6e-19 69.4 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 PFH31327.1 - 9.2e-14 51.3 0.1 2.6e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PFH31327.1 - 2.9e-06 27.2 1.0 0.0018 18.1 0.7 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 PFH31327.1 - 2.5e-05 24.8 0.1 5.4e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2190 PF09956.9 PFH31327.1 - 0.0074 16.8 1.7 0.0074 16.8 1.7 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2190) SpoIIM PF01944.17 PFH31327.1 - 2 8.4 0.0 2 8.4 0.0 4.2 5 0 0 5 5 5 0 Stage II sporulation protein M MerC PF03203.14 PFH31327.1 - 4 7.9 11.8 0.57 10.6 0.8 3.3 3 0 0 3 3 3 0 MerC mercury resistance protein zf-MIZ PF02891.20 PFH31328.1 - 3.7e-17 61.8 2.9 7.1e-17 60.9 2.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.6 PFH31328.1 - 3.3e-07 30.8 0.0 5.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 PINIT domain SAP PF02037.27 PFH31328.1 - 0.009 15.7 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 PFH31328.1 - 0.029 14.2 1.0 0.052 13.4 1.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 PFH31328.1 - 1.9 8.5 17.3 0.81 9.6 7.4 2.6 2 0 0 2 2 2 0 PHD-finger zinc_ribbon_10 PF10058.9 PFH31328.1 - 2.8 7.8 10.0 5 6.9 4.2 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein PP2C PF00481.21 PFH31330.1 - 1.4e-28 100.2 0.0 1.9e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PFH31330.1 - 0.02 14.8 0.1 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) ImpA_N PF06812.12 PFH31330.1 - 0.035 14.2 0.2 0.097 12.8 0.2 1.8 1 1 0 1 1 1 0 ImpA, N-terminal, type VI secretion system TPR_2 PF07719.17 PFH31331.1 - 5.3e-20 69.9 10.1 0.00031 20.6 1.3 7.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 PFH31331.1 - 2.6e-19 68.2 10.9 9e-06 25.3 1.1 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 PFH31331.1 - 6.9e-19 68.1 11.8 3e-05 24.5 0.1 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 PFH31331.1 - 8.4e-19 67.0 0.4 6.9e-07 28.9 0.0 6.7 5 1 2 7 7 7 3 TPR repeat TPR_14 PF13428.6 PFH31331.1 - 3.7e-18 64.7 6.5 0.001 19.7 0.0 7.8 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 PFH31331.1 - 1.1e-15 56.8 9.7 0.0077 16.5 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 PFH31331.1 - 9.2e-15 54.6 3.8 9.9e-07 28.8 0.4 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 PFH31331.1 - 2.4e-12 46.0 1.9 0.00049 20.1 1.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 PFH31331.1 - 7.2e-12 45.8 3.7 0.00022 21.8 0.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 PFH31331.1 - 2.5e-11 43.5 0.9 1.4 9.7 0.4 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 PFH31331.1 - 1.7e-10 41.0 10.1 8.2e-05 22.8 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 PFH31331.1 - 9.9e-09 35.4 7.3 0.0013 19.0 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 PFH31331.1 - 6.1e-06 26.7 11.5 0.00095 19.6 0.3 4.5 2 1 1 4 4 4 2 Bacterial transcriptional activator domain ANAPC3 PF12895.7 PFH31331.1 - 6.5e-05 23.1 14.8 0.4 10.9 0.8 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PFH31331.1 - 0.00012 21.8 7.4 1.8 8.8 0.1 5.9 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 PFH31331.1 - 0.0018 18.1 13.4 0.26 11.2 0.4 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 PFH31331.1 - 0.0069 15.6 1.3 5.7 6.1 0.0 3.0 1 1 1 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.10 PFH31331.1 - 0.0084 15.2 2.3 0.0084 15.1 0.2 1.9 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.9 PFH31331.1 - 0.03 14.0 4.1 0.55 9.9 0.1 3.0 1 1 0 2 2 2 0 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 PFH31331.1 - 0.34 10.6 1.4 8.4 6.0 0.0 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF410 PF04190.13 PFH31331.1 - 0.38 10.5 2.8 1.8 8.3 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF410) Svs_4_5_6 PF17381.2 PFH31332.1 - 0.22 12.5 6.2 3.6 8.6 0.4 2.2 2 0 0 2 2 2 0 Seminal vesicle secretory proteins 4/5/6 zf-CCCH PF00642.24 PFH31333.1 - 0.0053 16.6 0.1 0.0053 16.6 0.1 3.5 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAM2 PF07145.15 PFH31333.1 - 0.043 13.5 0.3 0.096 12.4 0.3 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region zf-CCCH_4 PF18044.1 PFH31333.1 - 0.1 12.4 9.7 0.19 11.6 1.0 3.0 3 0 0 3 3 3 0 CCCH-type zinc finger Torus PF16131.5 PFH31333.1 - 0.21 12.3 9.8 2.8 8.7 3.1 3.0 1 1 1 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 PFH31333.1 - 0.63 10.6 11.6 0.17 12.4 0.9 4.0 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger VIT1 PF01988.19 PFH31334.1 - 6.2 6.6 8.4 1 9.2 4.0 1.9 2 0 0 2 2 2 0 VIT family Jnk-SapK_ap_N PF09744.9 PFH31335.1 - 0.0028 17.9 3.1 0.0046 17.2 3.1 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Packaging_FI PF14000.6 PFH31335.1 - 0.015 15.7 0.6 0.028 14.9 0.6 1.4 1 0 0 1 1 1 0 DNA packaging protein FI HAUS-augmin3 PF14932.6 PFH31335.1 - 0.018 14.6 3.7 0.038 13.6 2.7 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 TMF_DNA_bd PF12329.8 PFH31335.1 - 0.099 12.7 7.8 0.046 13.7 4.6 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 PFH31335.1 - 2.7 8.5 11.3 3.9 8.0 9.8 1.8 2 0 0 2 2 2 0 Cell division protein ZapB GTP_EFTU PF00009.27 PFH31336.1 - 1e-33 116.5 0.2 1.3e-32 113.0 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PFH31336.1 - 1.8e-17 63.4 0.0 1.2e-12 47.8 0.0 2.5 2 0 0 2 2 2 2 Translation-initiation factor 2 MMR_HSR1 PF01926.23 PFH31336.1 - 1.4e-09 38.0 0.0 3.4e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PFH31336.1 - 5.9e-05 22.6 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 PFH31336.1 - 0.00057 19.5 0.2 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 PFH31336.1 - 0.002 17.6 0.0 0.0054 16.2 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 PFH31336.1 - 0.0057 16.5 0.7 0.8 9.6 0.2 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Roc PF08477.13 PFH31336.1 - 0.0058 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH31336.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Dynamin_N PF00350.23 PFH31336.1 - 0.12 12.4 0.0 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Dynamin family IF2_N PF04760.15 PFH31336.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region MBF1 PF08523.10 PFH31338.1 - 1.3e-18 67.2 1.6 1.3e-18 67.2 1.6 2.1 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 PFH31338.1 - 6.4e-15 55.0 0.1 9.7e-15 54.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 PFH31338.1 - 3e-10 40.3 0.0 4.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 PFH31338.1 - 2e-05 24.5 0.0 3.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 PFH31338.1 - 0.018 15.0 0.6 0.033 14.1 0.6 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_25 PF13413.6 PFH31338.1 - 0.026 14.4 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.6 PFH31338.1 - 0.078 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain PP2C PF00481.21 PFH31339.1 - 1.1e-32 113.7 0.0 2e-26 93.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 PFH31339.1 - 0.0037 16.9 0.0 0.041 13.5 0.0 2.3 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C PF00481.21 PFH31340.1 - 8.3e-13 48.6 0.0 1.9e-11 44.1 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C DUF538 PF04398.12 PFH31340.1 - 0.19 12.2 0.0 5.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF538 FtsJ PF01728.19 PFH31341.1 - 4.8e-23 82.2 0.0 2.8e-22 79.7 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase zf-NOSIP PF15906.5 PFH31342.1 - 1.2e-06 28.5 0.0 2.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Ima1_N PF09779.9 PFH31342.1 - 0.094 13.6 6.1 0.26 12.1 6.1 1.8 1 1 0 1 1 1 0 Ima1 N-terminal domain Transmemb_17 PF09799.9 PFH31344.1 - 3.2e-06 27.7 3.6 3.2e-06 27.7 3.6 1.6 1 1 0 1 1 1 1 Predicted membrane protein Adipogenin PF15202.6 PFH31344.1 - 7.7 6.6 12.8 0.35 10.9 1.4 2.6 2 1 0 2 2 2 0 Adipogenin Phasin_2 PF09361.10 PFH31345.1 - 0.052 13.8 0.7 0.12 12.7 0.7 1.6 1 0 0 1 1 1 0 Phasin protein SNF2_N PF00176.23 PFH31346.1 - 1e-56 192.2 0.0 1.9e-56 191.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PFH31346.1 - 4.1e-18 65.7 0.0 9.2e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 PFH31346.1 - 2.8e-09 36.9 0.0 5.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 PFH31346.1 - 1.5e-06 28.4 0.0 0.018 15.0 0.0 2.7 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 PFH31346.1 - 2.6e-05 23.5 0.0 6.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 PFH31346.1 - 0.02 14.6 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 SWI2/SNF2 ATPase CAF1C_H4-bd PF12265.8 PFH31347.1 - 3.6e-15 56.0 0.0 7.2e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 PFH31347.1 - 0.0015 19.3 5.9 1.8 9.6 0.0 5.4 5 1 0 5 5 5 2 WD domain, G-beta repeat Hira PF07569.11 PFH31347.1 - 0.01 15.6 0.0 3.2 7.4 0.0 3.2 3 0 0 3 3 3 1 TUP1-like enhancer of split Nop10p PF04135.12 PFH31348.1 - 3e-23 81.6 1.0 4e-23 81.2 1.0 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family PAP_assoc PF03828.19 PFH31349.1 - 6.6e-05 23.0 0.0 0.0055 16.9 0.0 2.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 PFH31349.1 - 0.00053 20.2 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 PFH31349.1 - 0.02 14.9 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase FAST_1 PF06743.15 PFH31350.1 - 0.013 15.5 0.4 8 6.5 0.2 3.7 2 1 2 4 4 4 0 FAST kinase-like protein, subdomain 1 zf-RanBP PF00641.18 PFH31351.1 - 7.6e-06 25.1 4.5 7.6e-06 25.1 4.5 3.3 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others Prenyltrans PF00432.21 PFH31352.1 - 1.1e-29 101.8 14.2 1.3e-09 37.6 2.5 7.1 7 0 0 7 7 7 6 Prenyltransferase and squalene oxidase repeat KH_1 PF00013.29 PFH31354.1 - 0.15 11.9 0.0 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 KH domain V-SNARE PF05008.15 PFH31358.1 - 3.4e-08 33.8 0.2 6.1e-08 32.9 0.2 1.5 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 PFH31358.1 - 5.2e-07 29.9 1.5 1.1e-06 28.8 0.9 1.9 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus TMEM156 PF15106.6 PFH31358.1 - 0.028 13.9 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 TMEM156 protein family DUF5345 PF17280.2 PFH31358.1 - 0.2 11.6 3.2 0.45 10.5 3.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Sec20 PF03908.13 PFH31358.1 - 0.21 11.5 1.5 0.25 11.3 0.4 1.7 2 0 0 2 2 2 0 Sec20 KLRAQ PF10205.9 PFH31360.1 - 0.69 10.2 4.3 10 6.5 0.1 3.3 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein Glucan_synthase PF02364.15 PFH31362.1 - 2.5e-154 515.5 18.0 6.8e-119 398.3 11.1 2.3 2 0 0 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 PFH31362.1 - 3.9e-13 49.8 2.4 1.8e-10 41.2 2.4 2.7 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_trans_2_3 PF13632.6 PFH31362.1 - 0.0031 17.5 0.7 0.0031 17.5 0.7 2.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 TetR PF13972.6 PFH31362.1 - 0.058 13.1 1.2 0.77 9.5 0.4 2.6 2 0 0 2 2 2 0 Bacterial transcriptional repressor Mre11_DNA_bind PF04152.14 PFH31363.1 - 2.4e-39 135.4 0.0 5.2e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 PFH31363.1 - 8.2e-14 52.6 0.1 2.7e-12 47.6 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PFH31363.1 - 0.001 19.3 0.0 0.048 13.9 0.0 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Proteasome PF00227.26 PFH31364.1 - 4.3e-52 176.4 0.0 5.2e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PFH31364.1 - 2e-13 49.7 0.0 4e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature G-patch PF01585.23 PFH31365.1 - 1.8e-12 47.0 0.1 4.7e-12 45.6 0.1 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 PFH31365.1 - 7.3e-10 38.8 0.1 7.3e-10 38.8 0.1 2.8 5 0 0 5 5 5 1 G-patch domain Coilin_N PF15862.5 PFH31365.1 - 0.027 14.3 0.1 0.027 14.3 0.1 3.0 1 1 2 3 3 3 0 Coilin N-terminus PAS_3 PF08447.12 PFH31366.1 - 0.00064 20.0 0.2 0.031 14.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold LRR_4 PF12799.7 PFH31367.1 - 4.6e-14 52.3 4.7 0.00023 21.5 0.0 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH31367.1 - 6.4e-08 32.2 10.3 0.00083 19.1 0.3 3.5 1 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 PFH31367.1 - 0.015 14.8 0.0 1.2 8.6 0.0 2.8 2 1 1 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 PFH31367.1 - 0.083 13.0 6.5 7.7 6.9 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 PFH31367.1 - 9.7 7.2 9.3 56 4.9 0.2 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat OTU PF02338.19 PFH31368.1 - 7e-06 26.6 0.0 1.3e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.7 PFH31368.1 - 0.0091 16.3 0.2 0.015 15.6 0.2 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) CobD_Cbib PF03186.13 PFH31368.1 - 0.13 11.4 0.0 0.35 10.0 0.0 1.6 2 0 0 2 2 2 0 CobD/Cbib protein Dynein_light PF01221.18 PFH31369.1 - 3.1e-25 88.3 1.7 3.6e-25 88.1 1.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Phi-29_GP4 PF05464.11 PFH31369.1 - 0.023 14.9 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) DUF4070 PF13282.6 PFH31369.1 - 0.065 13.4 0.1 0.07 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) Glycos_transf_2 PF00535.26 PFH31370.1 - 1.8e-33 115.7 0.0 2.3e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PFH31370.1 - 6.1e-12 45.9 0.0 1.5e-11 44.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 PFH31370.1 - 0.0041 16.6 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 PFH31370.1 - 0.0086 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Lipase_3 PF01764.25 PFH31371.1 - 6.1e-16 58.6 0.0 9.1e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) UPF0242 PF06785.11 PFH31372.1 - 0.31 11.1 6.2 0.94 9.5 5.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TRAF_BIRC3_bd PF16673.5 PFH31373.1 - 0.16 11.7 0.0 0.16 11.7 0.0 4.5 5 0 0 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain Peptidase_A3 PF02160.15 PFH31373.1 - 0.19 11.2 0.1 0.59 9.6 0.1 1.8 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) TPD52 PF04201.15 PFH31373.1 - 2.5 7.7 12.2 0.1 12.2 3.1 3.0 2 0 0 2 2 2 0 Tumour protein D52 family GvpK PF05121.12 PFH31373.1 - 3.7 7.6 9.2 3.1 7.9 0.5 3.7 3 0 0 3 3 3 0 Gas vesicle protein K TSP_1 PF00090.19 PFH31376.1 - 8e-05 22.8 6.7 8e-05 22.8 6.7 3.2 2 1 1 3 3 3 1 Thrombospondin type 1 domain UCH PF00443.29 PFH31377.1 - 7.4e-31 107.6 0.0 1.1e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PFH31377.1 - 1.6e-12 47.7 0.0 8e-09 35.5 0.0 2.9 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UPF0020 PF01170.18 PFH31380.1 - 2.3e-11 43.8 0.0 1.8e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 PFH31380.1 - 3.2e-05 23.8 0.0 0.0054 16.5 0.0 2.2 2 0 0 2 2 2 2 DNA methylase THUMP PF02926.17 PFH31380.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 THUMP domain N6_Mtase PF02384.16 PFH31380.1 - 0.049 12.9 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 N-6 DNA Methylase DUF4680 PF15730.5 PFH31380.1 - 1.5 9.2 0.0 1.5 9.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4680) DEC-1_N PF04625.13 PFH31380.1 - 7.2 5.5 6.5 6 5.8 4.6 1.8 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region PDZ_3 PF17815.1 PFH31381.1 - 1.8e-48 164.1 0.0 2.7e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 PFH31381.1 - 1.3e-20 74.8 2.1 3.2e-20 73.5 0.5 2.2 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 PFH31381.1 - 4.8e-12 46.2 0.6 8.2e-12 45.4 0.6 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 PFH31381.1 - 7.4e-08 32.6 0.1 2.2e-06 27.9 0.0 2.7 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 PFH31381.1 - 2.7e-06 27.6 0.2 8.5e-06 26.0 0.1 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 PFH31381.1 - 8e-05 22.4 0.3 0.024 14.5 0.1 2.6 2 0 0 2 2 2 2 PDZ domain Peptidase_S46 PF10459.9 PFH31381.1 - 0.027 13.1 0.0 0.048 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase S46 DUF2505 PF10698.9 PFH31381.1 - 0.24 11.5 1.6 0.56 10.3 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2505) Ras PF00071.22 PFH31383.1 - 3.5e-14 52.7 0.0 7.7e-11 41.9 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 PFH31383.1 - 8.1e-06 26.1 0.0 0.0025 18.0 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 PFH31383.1 - 0.035 14.2 0.3 0.13 12.4 0.3 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 PFH31383.1 - 0.095 12.2 0.0 7.5 6.0 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 PFH31383.1 - 0.16 12.1 0.1 0.18 11.8 0.1 1.4 1 1 0 1 1 1 0 Dynamin family TniB PF05621.11 PFH31383.1 - 0.17 11.3 0.0 0.82 9.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein Abhydrolase_1 PF00561.20 PFH31384.1 - 0.009 15.7 0.0 0.024 14.3 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3450 PF11932.8 PFH31385.1 - 0.0011 18.4 2.1 0.0011 18.4 2.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3450) CortBP2 PF09727.9 PFH31385.1 - 0.0013 18.6 9.1 0.0013 18.6 9.1 3.3 3 1 0 4 4 4 1 Cortactin-binding protein-2 Metal_hydrol PF10118.9 PFH31385.1 - 0.044 13.5 4.0 0.075 12.8 4.0 1.3 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase Lipoprotein_20 PF13942.6 PFH31385.1 - 0.33 10.9 16.8 0.074 13.0 1.5 2.5 2 0 0 2 2 2 0 YfhG lipoprotein Cnn_1N PF07989.11 PFH31385.1 - 1.8 8.8 14.1 2.8 8.1 4.5 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Dynein_C PF18199.1 PFH31385.1 - 8.4 5.5 10.0 0.3 10.3 0.3 2.1 2 0 0 2 2 2 0 Dynein heavy chain C-terminal domain DUF547 PF04784.14 PFH31386.1 - 2.6e-32 111.4 0.0 5.3e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DEP PF00610.21 PFH31386.1 - 1.1e-07 31.8 0.0 2.3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glutaredoxin PF00462.24 PFH31386.1 - 9.1e-07 29.0 0.2 0.0053 17.0 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin Med3 PF11593.8 PFH31387.1 - 2 7.5 6.1 2.7 7.1 6.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PWWP PF00855.17 PFH31388.1 - 1.9e-07 31.4 0.1 1.9e-07 31.4 0.1 3.8 3 1 0 3 3 3 1 PWWP domain zf-CCCH PF00642.24 PFH31388.1 - 0.94 9.5 6.9 1.7 8.6 6.9 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2009 PF09418.10 PFH31389.1 - 3.1e-198 659.4 0.1 8e-129 430.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2009) zf-RING_2 PF13639.6 PFH31390.1 - 5.2e-12 45.9 7.4 5.2e-12 45.9 7.4 1.9 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 PFH31390.1 - 6.4e-09 36.0 3.2 2.1e-08 34.3 3.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PFH31390.1 - 4.7e-08 32.8 5.6 1.1e-07 31.6 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PFH31390.1 - 2.7e-07 30.2 1.7 6.2e-07 29.0 1.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 PFH31390.1 - 6.7e-06 25.9 4.6 1.4e-05 24.9 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH31390.1 - 1.7e-05 24.8 2.3 4e-05 23.5 2.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PFH31390.1 - 3.2e-05 23.8 3.7 6.4e-05 22.8 3.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PFH31390.1 - 0.00041 20.1 3.8 0.00082 19.2 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PFH31390.1 - 0.0014 18.6 3.5 0.007 16.4 2.9 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 PFH31390.1 - 0.0026 17.4 3.9 0.068 12.8 3.4 2.4 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 PFH31390.1 - 0.004 17.0 3.3 0.004 17.0 3.3 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 PFH31390.1 - 0.21 11.7 6.5 0.52 10.5 6.5 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 PFH31390.1 - 0.59 10.2 2.9 1.3 9.1 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger GDA1_CD39 PF01150.17 PFH31391.1 - 4.6e-10 38.8 0.0 2.2e-09 36.5 0.0 2.0 2 1 0 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family AF-4 PF05110.13 PFH31391.1 - 1.3 7.1 4.8 1.7 6.6 4.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Alpha_GJ PF03229.13 PFH31391.1 - 7.5 7.1 11.7 19 5.8 11.7 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J YabA PF06156.13 PFH31392.1 - 0.15 12.7 0.9 0.42 11.3 0.9 1.7 1 0 0 1 1 1 0 Initiation control protein YabA UPF0242 PF06785.11 PFH31392.1 - 0.19 11.8 1.3 0.37 10.9 1.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cep57_MT_bd PF06657.13 PFH31392.1 - 0.28 11.6 5.0 0.25 11.8 3.1 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Takusan PF04822.13 PFH31392.1 - 1.5 8.8 4.7 7.8 6.5 2.7 2.3 2 0 0 2 2 2 0 Takusan Ribosomal_S14 PF00253.21 PFH31393.1 - 0.0089 15.8 1.6 0.0089 15.8 1.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e DUF1279 PF06916.13 PFH31394.1 - 6.7e-12 45.8 0.0 1.1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) zf-HIT PF04438.16 PFH31395.1 - 0.0066 16.3 18.9 0.044 13.7 18.9 2.1 1 1 0 1 1 1 1 HIT zinc finger Caskin1-CID PF16600.5 PFH31395.1 - 0.4 11.3 3.9 0.99 10.0 3.9 1.6 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain YEATS PF03366.16 PFH31397.1 - 0.15 12.1 18.1 8.6 6.4 0.1 7.9 4 2 3 8 8 8 0 YEATS family PIG-U PF06728.13 PFH31398.1 - 4.4e-88 295.9 7.3 5.4e-88 295.6 7.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 PFH31398.1 - 0.0055 16.4 9.4 0.0093 15.7 9.4 1.3 1 0 0 1 1 1 1 8TM Microsporidial transmembrane domain UvrD-helicase PF00580.21 PFH31400.1 - 3.7e-40 138.4 0.0 7.2e-24 84.9 0.0 3.7 3 1 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 PFH31400.1 - 2.8e-29 102.6 0.0 5.4e-22 78.6 0.0 4.1 4 0 0 4 4 4 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 PFH31400.1 - 6.4e-18 65.5 0.0 2.3e-13 50.7 0.0 4.1 4 1 0 4 4 4 2 AAA domain UvrD_C_2 PF13538.6 PFH31400.1 - 2.5e-09 36.8 0.1 0.00041 20.1 0.0 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain PAP2_3 PF14378.6 PFH31400.1 - 0.024 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 PAP2 superfamily Viral_helicase1 PF01443.18 PFH31400.1 - 0.029 14.1 0.2 2.3 7.9 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Slx4 PF09494.10 PFH31401.1 - 8.3e-08 32.1 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Slx4 endonuclease MAS20 PF02064.15 PFH31401.1 - 1.5 8.9 5.0 10 6.3 5.0 2.5 1 0 0 1 1 1 0 MAS20 protein import receptor Topoisom_bac PF01131.20 PFH31402.1 - 1.4e-69 235.1 0.0 2.7e-28 99.1 0.0 5.7 5 1 0 5 5 5 4 DNA topoisomerase Toprim PF01751.22 PFH31402.1 - 4.5e-13 49.3 0.0 2.9e-12 46.7 0.0 2.2 1 1 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 PFH31402.1 - 7.7e-10 38.4 1.8 1.9e-09 37.1 1.8 1.6 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger WD40 PF00400.32 PFH31403.1 - 2.9e-09 37.4 4.7 0.18 12.8 0.0 6.5 6 0 0 6 6 6 2 WD domain, G-beta repeat Paralemmin PF03285.15 PFH31403.1 - 0.00094 18.8 8.4 0.0017 18.0 8.4 1.4 1 0 0 1 1 1 1 Paralemmin GIDA_assoc PF13932.6 PFH31403.1 - 0.44 10.7 3.0 0.86 9.7 3.0 1.4 1 0 0 1 1 1 0 GidA associated domain AAA PF00004.29 PFH31404.1 - 4.2e-40 137.2 0.0 9.4e-40 136.1 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PFH31404.1 - 3.2e-09 36.4 0.0 7.9e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PFH31404.1 - 3e-05 24.3 0.1 0.0063 16.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PFH31404.1 - 3.7e-05 23.7 0.1 0.00016 21.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PFH31404.1 - 0.00026 21.4 0.2 0.0019 18.6 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 PFH31404.1 - 0.001 18.9 0.0 0.0045 16.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PFH31404.1 - 0.002 18.2 0.0 0.0058 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 PFH31404.1 - 0.011 16.2 0.0 0.031 14.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PFH31404.1 - 0.012 15.9 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PFH31404.1 - 0.016 14.9 0.0 0.13 11.9 0.0 2.4 4 0 0 4 4 4 0 AAA domain AAA_7 PF12775.7 PFH31404.1 - 0.019 14.5 0.0 0.047 13.2 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 PFH31404.1 - 0.03 14.5 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 PFH31404.1 - 0.034 13.3 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 PFH31404.1 - 0.066 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 PFH31404.1 - 0.068 12.9 0.6 0.11 12.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 PFH31404.1 - 0.083 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 PFH31404.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 PFH31404.1 - 0.13 11.2 0.0 0.3 10.1 0.0 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein GDA1_CD39 PF01150.17 PFH31406.1 - 0.0083 14.8 0.0 0.01 14.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AKAP28 PF14469.6 PFH31406.1 - 0.13 12.0 0.1 0.19 11.5 0.1 1.1 1 0 0 1 1 1 0 28 kDa A-kinase anchor zf-C2H2_2 PF12756.7 PFH31407.1 - 0.19 12.1 0.1 0.33 11.3 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Rad21_Rec8_N PF04825.13 PFH31408.1 - 0.0014 18.7 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 PFH31408.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein SDA1 PF05285.12 PFH31409.1 - 0.37 10.2 17.8 0.54 9.6 17.8 1.3 1 0 0 1 1 1 0 SDA1 Rad51 PF08423.11 PFH31410.1 - 2.1e-09 37.0 1.7 0.0035 16.6 0.2 3.6 4 0 0 4 4 4 3 Rad51 AAA_25 PF13481.6 PFH31410.1 - 5.1e-06 26.2 0.3 0.00015 21.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 PFH31410.1 - 0.01 16.1 0.1 0.039 14.2 0.1 1.9 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 PFH31410.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 PFH31410.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 PFH31410.1 - 0.13 12.0 0.0 5.7 6.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 PFH31410.1 - 0.28 11.6 0.1 0.28 11.6 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain XPG_N PF00752.17 PFH31411.1 - 4.1e-14 52.9 0.0 2.2e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 XPG N-terminal domain XPG_I PF00867.18 PFH31411.1 - 3.2e-12 46.6 0.5 2.4e-11 43.8 0.3 2.2 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 PFH31411.1 - 0.0008 18.9 0.1 0.0014 18.2 0.1 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 PFH31411.1 - 0.067 13.8 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF4054 PF13262.6 PFH31411.1 - 0.1 12.7 0.3 0.25 11.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) zf-C2H2_11 PF16622.5 PFH31411.1 - 0.16 11.8 0.9 0.36 10.6 0.9 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type TetR_C_28 PF17937.1 PFH31411.1 - 1.2 9.7 5.4 0.59 10.6 2.4 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Mito_carr PF00153.27 PFH31412.1 - 9.1e-55 182.6 1.2 3e-19 68.7 0.1 4.6 4 1 0 4 4 4 4 Mitochondrial carrier protein LSM PF01423.22 PFH31413.1 - 3.9e-16 58.5 0.0 6e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PFH31413.1 - 0.23 11.6 0.0 0.43 10.7 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain HKR_ArcB_TM PF18415.1 PFH31414.1 - 1 10.2 6.4 6.4 7.6 2.8 3.4 3 0 0 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain UBM PF14377.6 PFH31415.1 - 0.014 14.8 0.2 0.03 13.8 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin binding region Peptidase_C14 PF00656.22 PFH31416.1 - 4.8e-25 88.9 0.0 7.1e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Caspase domain CCDC24 PF15669.5 PFH31416.1 - 0.0034 17.3 0.3 0.0064 16.4 0.3 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family Mito_carr PF00153.27 PFH31417.1 - 7.2e-31 106.0 9.1 1.8e-16 59.8 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein ArsB PF02040.15 PFH31417.1 - 0.087 12.1 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 Arsenical pump membrane protein DTW PF03942.15 PFH31418.1 - 0.1 12.3 0.6 0.18 11.5 0.6 1.3 1 0 0 1 1 1 0 DTW domain DTW PF03942.15 PFH31419.1 - 0.093 12.4 0.6 0.16 11.7 0.6 1.3 1 0 0 1 1 1 0 DTW domain DUF3395 PF11875.8 PFH31420.1 - 5.8 6.8 5.6 18 5.2 5.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3395) Ribosomal_L12 PF00542.19 PFH31422.1 - 2.7e-24 85.3 9.8 5.8e-21 74.6 7.3 2.5 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 PFH31422.1 - 0.031 14.0 0.1 0.031 14.0 0.1 4.9 4 1 0 4 4 4 0 Ribosomal protein L7/L12 dimerisation domain LRR_4 PF12799.7 PFH31423.1 - 3.3e-16 59.1 11.6 1.6e-05 25.1 0.1 5.4 2 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH31423.1 - 3.9e-12 45.8 5.7 0.0022 17.7 0.6 4.7 3 2 2 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 PFH31423.1 - 4.6e-10 39.3 4.0 5.5e-06 26.0 0.6 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 PFH31423.1 - 0.0037 17.6 9.7 6.2 7.8 0.0 6.1 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 PFH31423.1 - 0.0044 17.0 12.3 0.54 10.5 0.1 6.2 6 0 0 6 6 6 1 Leucine Rich repeat Snurportin1 PF11538.8 PFH31423.1 - 3.7 7.8 8.4 2.6 8.3 6.7 1.7 1 1 0 1 1 1 0 Snurportin1 adh_short_C2 PF13561.6 PFH31424.1 - 2.2e-51 174.7 0.4 2e-47 161.7 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PFH31424.1 - 4e-11 42.7 0.1 1.1e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Enoyl_reductase PF12241.8 PFH31424.1 - 0.0024 17.3 0.2 0.29 10.5 0.0 2.3 1 1 0 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region ChpA-C PF03777.13 PFH31424.1 - 0.011 15.5 1.8 0.032 14.1 1.8 1.7 1 0 0 1 1 1 0 ChpA-C K_channel_TID PF07941.11 PFH31424.1 - 0.25 11.8 3.5 0.92 10.0 3.5 1.9 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Es2 PF09751.9 PFH31425.1 - 5.7e-16 59.3 6.9 5.7e-16 59.3 6.9 3.1 1 1 1 2 2 2 1 Nuclear protein Es2 Uteroglobin PF01099.17 PFH31426.1 - 0.072 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Uteroglobin family TrbC PF04956.13 PFH31427.1 - 0.15 12.3 0.1 0.21 11.8 0.1 1.1 1 0 0 1 1 1 0 TrbC/VIRB2 family tRNA-synt_1b PF00579.25 PFH31430.1 - 8e-59 199.3 0.0 9.9e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF3683 PF12447.8 PFH31430.1 - 0.026 14.6 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) DUF1965 PF09248.10 PFH31430.1 - 0.13 12.1 0.0 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) Histone PF00125.24 PFH31431.1 - 4.4e-16 59.4 0.5 5.2e-16 59.2 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PFH31431.1 - 0.00015 21.9 0.2 0.00035 20.8 0.2 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 PFH31431.1 - 0.00019 21.9 0.0 0.00039 20.9 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A EF-hand_7 PF13499.6 PFH31434.1 - 1.8e-24 86.0 8.2 2.3e-09 37.6 0.4 4.1 3 1 1 4 4 4 4 EF-hand domain pair Metallophos PF00149.28 PFH31434.1 - 3.8e-23 83.1 0.1 1e-22 81.6 0.1 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 PFH31434.1 - 3e-15 54.5 6.3 0.00062 19.1 0.1 6.2 6 0 0 6 6 6 3 EF hand CAP_GLY PF01302.25 PFH31434.1 - 2.9e-14 52.8 0.2 7e-14 51.6 0.2 1.7 1 0 0 1 1 1 1 CAP-Gly domain EF-hand_8 PF13833.6 PFH31434.1 - 1.4e-13 50.4 6.1 2e-08 34.0 0.5 4.5 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH31434.1 - 2e-13 49.1 6.4 0.029 14.3 0.1 6.6 6 0 0 6 6 6 3 EF-hand domain PPP5 PF08321.12 PFH31434.1 - 6.4e-06 26.4 0.1 5.9e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 PPP5 TPR repeat region EF-hand_11 PF08976.11 PFH31434.1 - 4.6e-05 24.2 0.3 0.0088 16.9 0.0 3.7 3 1 1 4 4 3 1 EF-hand domain IQ PF00612.27 PFH31434.1 - 0.00057 19.4 2.4 0.0018 17.9 2.4 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif EF-hand_5 PF13202.6 PFH31434.1 - 0.0039 16.6 4.9 0.058 12.9 0.1 4.5 5 0 0 5 5 5 1 EF hand EF-hand_4 PF12763.7 PFH31434.1 - 0.016 15.2 0.8 0.88 9.6 0.1 3.6 4 1 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand OCRE PF17780.1 PFH31435.1 - 0.084 12.9 2.6 0.2 11.7 2.6 1.6 1 0 0 1 1 1 0 OCRE domain eIF-5a PF01287.20 PFH31438.1 - 2.6e-26 91.5 0.4 4.1e-26 90.9 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 PFH31438.1 - 0.00023 21.1 0.1 0.0004 20.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain zf-RanBP PF00641.18 PFH31439.1 - 0.031 13.6 6.6 0.079 12.3 6.6 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zinc_ribbon_2 PF13240.6 PFH31439.1 - 0.95 9.3 3.8 1.8 8.4 3.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain HSP70 PF00012.20 PFH31440.1 - 3.2e-266 884.3 12.0 4.8e-266 883.7 12.0 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PFH31440.1 - 1.5e-13 50.3 5.2 5.6e-13 48.4 2.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 PFH31440.1 - 0.00057 20.3 0.3 0.39 11.2 0.1 3.0 2 0 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.16 PFH31440.1 - 0.006 16.3 0.1 0.026 14.3 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain TMIE PF16038.5 PFH31440.1 - 0.068 13.0 1.0 0.25 11.2 1.0 2.0 1 0 0 1 1 1 0 TMIE protein PPDK_N PF01326.19 PFH31440.1 - 0.11 11.8 3.5 0.24 10.6 1.2 2.1 2 0 0 2 2 2 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain HBS1_N PF08938.10 PFH31440.1 - 0.35 11.2 3.5 1.4 9.3 3.5 2.1 1 0 0 1 1 1 0 HBS1 N-terminus PA28_beta PF02252.18 PFH31441.1 - 1.9e-56 189.8 1.0 2.5e-56 189.4 0.3 1.5 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 PFH31441.1 - 0.0025 17.8 1.3 0.0049 16.9 0.1 2.1 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit MORN PF02493.20 PFH31442.1 - 4.7e-21 73.4 47.1 4.4e-07 29.4 3.2 8.0 9 0 0 9 9 9 5 MORN repeat AP2 PF00847.20 PFH31443.1 - 7.7e-10 38.9 0.0 1.6e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 AP2 domain V-SNARE_C PF12352.8 PFH31445.1 - 1.3e-05 25.4 0.1 7.4e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Med11 PF10280.9 PFH31445.1 - 0.16 12.4 1.3 8.4 6.9 0.3 2.8 2 1 1 3 3 3 0 Mediator complex protein ATP_synt_H PF05493.13 PFH31445.1 - 0.16 12.4 0.6 0.31 11.5 0.6 1.4 1 0 0 1 1 1 0 ATP synthase subunit H tRNA-synt_2b PF00587.25 PFH31446.1 - 1.3e-36 126.3 0.0 2.1e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 PFH31446.1 - 4.4e-22 78.4 5.0 9.1e-22 77.3 5.0 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Succ_DH_flav_C PF02910.20 PFH31446.1 - 0.018 15.0 0.4 0.036 14.0 0.4 1.5 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term MobL PF18555.1 PFH31446.1 - 0.062 12.5 0.3 0.092 12.0 0.3 1.1 1 0 0 1 1 1 0 MobL relaxases Uso1_p115_C PF04871.13 PFH31446.1 - 0.32 11.4 6.7 1.7 9.1 4.0 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 PFH31446.1 - 0.74 8.6 6.4 1.2 8.0 6.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Ribosomal_60s PF00428.19 PFH31446.1 - 0.79 10.4 6.8 0.97 10.1 2.8 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_MLP1_2 PF07926.12 PFH31446.1 - 2.4 8.2 8.8 5.3 7.1 8.8 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TCTP PF00838.17 PFH31447.1 - 3.7e-56 190.0 0.8 4.1e-56 189.9 0.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein MAR_sialic_bdg PF10564.9 PFH31448.1 - 3.1e-47 158.5 24.4 9.1e-19 67.3 4.5 3.5 2 1 1 3 3 3 3 Sialic-acid binding micronemal adhesive repeat MgsA_C PF12002.8 PFH31449.1 - 2e-50 171.0 0.1 3.7e-50 170.1 0.1 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 PFH31449.1 - 4.6e-23 81.3 0.2 1.5e-22 79.7 0.2 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 PFH31449.1 - 3.2e-13 50.3 0.1 2.9e-12 47.1 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PFH31449.1 - 6.1e-09 35.8 0.0 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PFH31449.1 - 8.5e-07 29.0 0.0 2.4e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PFH31449.1 - 4.4e-06 26.2 0.4 9.3e-05 21.9 0.4 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 PFH31449.1 - 1.8e-05 25.2 6.3 0.043 14.2 0.3 3.6 2 1 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 PFH31449.1 - 3e-05 23.8 0.0 0.00019 21.2 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 PFH31449.1 - 0.00019 21.7 0.1 0.001 19.3 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 PFH31449.1 - 0.00028 20.9 0.0 0.00088 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 PFH31449.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_25 PF13481.6 PFH31449.1 - 0.018 14.6 0.8 0.036 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 PFH31449.1 - 0.037 13.8 0.0 0.074 12.8 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit TIP49 PF06068.13 PFH31449.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 PFH31449.1 - 0.16 12.3 0.2 2.5 8.4 0.2 2.3 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 PFH31449.1 - 0.17 12.0 0.1 1.1 9.4 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 PFH31449.1 - 0.24 11.4 0.1 9.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit UQ_con PF00179.26 PFH31451.1 - 2.1e-12 46.9 0.0 2.8e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PFH31451.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Cation_efflux PF01545.21 PFH31452.1 - 1.2e-46 159.0 5.2 1.4e-46 158.7 5.2 1.1 1 0 0 1 1 1 1 Cation efflux family XPG_I PF00867.18 PFH31453.1 - 2.2e-29 101.6 0.0 6.8e-29 100.1 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 PFH31453.1 - 1.3e-26 93.0 0.0 4.3e-26 91.3 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 PFH31453.1 - 1.8e-06 28.5 0.0 9.9e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold SUKH-4 PF14435.6 PFH31453.1 - 0.0063 16.6 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 SUKH-4 immunity protein DUF5106 PF17127.4 PFH31453.1 - 0.037 14.3 0.3 0.091 13.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) NPR3 PF03666.13 PFH31454.1 - 2 7.1 9.0 4.6 5.9 9.0 1.6 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAG PF04092.13 PFH31455.1 - 2.2e-43 148.2 14.3 7.6e-23 81.7 1.9 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH31456.1 - 1.2e-60 204.0 23.5 2.5e-20 73.6 5.8 3.1 3 0 0 3 3 3 3 SRS domain DNA_pol_D_N PF18018.1 PFH31456.1 - 0.0089 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Hepar_II_III PF07940.13 PFH31456.1 - 0.017 14.7 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Heparinase II/III-like protein SAG PF04092.13 PFH31457.1 - 2.1e-13 51.2 0.1 2.4e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 SRS domain Brix PF04427.18 PFH31458.1 - 1.8e-26 93.5 0.3 1.8e-26 93.5 0.3 1.6 2 0 0 2 2 2 1 Brix domain DUF2415 PF10313.9 PFH31458.1 - 0.093 12.7 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) NAM-associated PF14303.6 PFH31458.1 - 2.8 8.6 17.6 4.6 7.9 17.6 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CPBP PF02517.16 PFH31460.1 - 3.9e-16 59.2 5.3 3.9e-16 59.2 5.3 2.5 3 0 0 3 3 3 1 CPBP intramembrane metalloprotease ACBP PF00887.19 PFH31462.1 - 5e-29 100.3 1.5 6.4e-29 100.0 1.5 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Cytochrom_B562 PF07361.11 PFH31462.1 - 0.034 14.8 0.1 0.057 14.1 0.1 1.3 1 0 0 1 1 1 0 Cytochrome b562 Peptidase_C48 PF02902.19 PFH31466.1 - 1e-09 38.6 0.1 1.6e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.19 PFH31467.1 - 0.00054 19.9 0.0 0.0015 18.4 0.0 1.7 1 1 1 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF1525 PF07511.11 PFH31467.1 - 0.021 15.0 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) JAB PF01398.21 PFH31468.1 - 1.4e-10 41.2 0.1 4.9e-09 36.2 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HU-DNA_bdg PF14848.6 PFH31468.1 - 0.059 13.4 0.1 4.3 7.4 0.0 2.3 1 1 1 2 2 2 0 DNA-binding domain SRAP PF02586.14 PFH31469.1 - 1.2e-40 139.4 0.0 5.3e-39 134.0 0.0 2.4 2 1 0 2 2 2 1 SOS response associated peptidase (SRAP) TP2 PF01254.18 PFH31469.1 - 0.41 11.2 8.9 0.68 10.6 7.8 2.0 1 1 0 1 1 1 0 Nuclear transition protein 2 DEAD PF00270.29 PFH31470.1 - 1.5e-39 135.6 0.1 3.2e-39 134.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH31470.1 - 1.9e-20 73.3 0.0 7e-18 65.0 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PFH31470.1 - 1.9e-07 31.2 0.1 6e-07 29.6 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PFH31470.1 - 4.1e-05 23.6 0.0 0.00085 19.4 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PFH31470.1 - 0.1 12.8 0.1 0.34 11.2 0.1 1.9 1 0 0 1 1 1 0 AAA domain DUF1682 PF07946.14 PFH31470.1 - 1.4 8.0 11.8 0.62 9.2 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) DUF913 PF06025.12 PFH31470.1 - 3.8 6.4 15.1 9 5.2 0.1 4.1 4 0 0 4 4 4 0 Domain of Unknown Function (DUF913) ATP_synt_H PF05493.13 PFH31472.1 - 6.7e-19 68.1 4.9 8.5e-19 67.8 4.9 1.2 1 0 0 1 1 1 1 ATP synthase subunit H Sarcolipin PF05366.11 PFH31472.1 - 0.63 9.8 7.3 0.63 9.8 3.0 2.1 2 0 0 2 2 2 0 Sarcolipin Orf78 PF06024.12 PFH31472.1 - 1.1 9.6 2.6 2.4 8.5 0.0 2.0 1 1 1 2 2 2 0 Orf78 (ac78) APG17 PF04108.12 PFH31473.1 - 0.00069 18.8 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF3357 PF11837.8 PFH31473.1 - 0.12 12.8 4.7 0.73 10.3 4.7 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) ANAPC4_WD40 PF12894.7 PFH31474.1 - 0.0068 16.7 0.0 1.9 8.9 0.0 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PFH31474.1 - 0.0079 17.0 0.0 0.38 11.7 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat EF-hand_7 PF13499.6 PFH31475.1 - 8.6e-05 22.9 0.7 0.0029 18.0 0.7 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PFH31475.1 - 0.0029 17.0 0.2 0.15 11.7 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 PFH31475.1 - 0.0046 16.8 0.8 3 7.7 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH31475.1 - 0.03 14.3 1.2 0.19 11.8 0.2 2.6 3 0 0 3 3 3 0 EF-hand domain eIF3_p135 PF12807.7 PFH31477.1 - 1.7e-24 86.8 0.0 5.1e-24 85.3 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 PFH31477.1 - 1.5e-13 50.9 0.0 2.8e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term CLU PF13236.6 PFH31477.1 - 3.8e-08 33.4 0.0 0.0031 17.4 0.0 2.5 2 0 0 2 2 2 2 Clustered mitochondria TPR_12 PF13424.6 PFH31477.1 - 1.7e-07 31.4 0.1 0.00036 20.8 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PFH31477.1 - 0.00096 19.1 0.6 0.54 10.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PFH31477.1 - 0.0025 17.2 2.8 0.31 10.4 0.0 2.3 2 0 0 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 PFH31477.1 - 0.1 12.5 0.1 1.2 9.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF727 PF05303.12 PFH31477.1 - 0.16 12.1 0.0 1.2 9.2 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF727) UPF0016 PF01169.19 PFH31478.1 - 6.1e-28 97.0 19.0 8.1e-15 54.9 4.6 3.6 3 0 0 3 3 3 3 Uncharacterized protein family UPF0016 LysE PF01810.18 PFH31478.1 - 0.054 12.9 2.6 2.5 7.5 0.1 2.8 2 1 0 2 2 2 0 LysE type translocator Cyclin PF08613.11 PFH31480.1 - 1.2e-09 38.8 0.7 2.3e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 PFH31480.1 - 5.9e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TPR_2 PF07719.17 PFH31481.1 - 9.7e-09 34.7 15.5 0.0026 17.8 0.6 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 PFH31481.1 - 1.2e-05 25.3 0.3 1.2e-05 25.3 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 PFH31481.1 - 3.1e-05 23.6 16.6 0.0023 17.7 1.8 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 PFH31481.1 - 0.00019 21.6 8.2 0.27 11.6 0.1 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 PFH31481.1 - 0.00019 21.4 7.0 0.014 15.6 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 PFH31481.1 - 0.00021 21.1 4.5 0.011 15.6 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH31481.1 - 0.00062 19.9 6.7 0.0036 17.5 1.8 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PFH31481.1 - 0.0024 18.4 7.8 11 6.9 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat SPO22 PF08631.10 PFH31481.1 - 0.0048 16.4 0.6 0.0095 15.5 0.6 1.4 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 PFH31481.1 - 0.0071 16.8 7.7 0.41 11.2 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 PFH31481.1 - 0.029 14.0 0.6 0.8 9.4 0.8 2.5 2 0 0 2 2 2 0 TPR repeat MIT PF04212.18 PFH31481.1 - 0.085 12.9 1.5 1.5 9.0 1.2 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 PFH31481.1 - 0.12 13.0 6.6 2 9.1 0.3 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PFH31481.1 - 0.36 11.0 2.8 25 5.0 0.1 3.3 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 PFH31481.1 - 0.52 11.3 2.6 32 5.7 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 PFH31481.1 - 4.2 7.5 10.2 0.29 11.1 0.9 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4123 PF13503.6 PFH31483.1 - 0.21 12.0 1.1 0.58 10.6 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4123) AbfS_sensor PF18225.1 PFH31484.1 - 0.09 12.7 0.3 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Sensor histidine kinase (AbfS) sensor domain DNA_pol_A_exo1 PF01612.20 PFH31485.1 - 2.2e-14 53.6 0.0 5.4e-14 52.3 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease dsrm PF00035.26 PFH31485.1 - 0.012 16.3 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif PfkB PF00294.24 PFH31486.1 - 1.5e-47 162.4 0.4 4.3e-47 160.9 0.4 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DHHC PF01529.20 PFH31487.1 - 1.7e-36 125.2 5.8 1.7e-36 125.2 5.8 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pkinase PF00069.25 PFH31488.1 - 1.7e-26 93.1 0.1 7.7e-08 32.0 0.1 4.2 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31488.1 - 1.1e-08 34.7 0.8 0.039 13.2 0.5 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase EF-hand_7 PF13499.6 PFH31489.1 - 0.022 15.2 0.0 0.11 12.9 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain pair CSN8_PSD8_EIF3K PF10075.9 PFH31490.1 - 9.5e-13 48.3 1.7 1.5e-11 44.5 0.1 2.8 3 1 0 3 3 3 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 PFH31490.1 - 0.0043 16.5 0.1 0.013 14.9 0.0 1.8 1 1 1 2 2 2 1 SAC3/GANP family Fis1_TPR_C PF14853.6 PFH31490.1 - 0.031 14.3 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TSC22 PF01166.18 PFH31491.1 - 0.019 15.3 0.6 0.046 14.0 0.0 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family SICA_alpha PF12887.7 PFH31491.1 - 0.077 12.9 1.8 7.4 6.4 0.1 2.2 2 0 0 2 2 2 0 SICA extracellular alpha domain Phage_GP20 PF06810.11 PFH31491.1 - 0.23 11.3 4.5 0.091 12.6 0.7 2.1 2 1 0 2 2 2 0 Phage minor structural protein GP20 DUF4094 PF13334.6 PFH31491.1 - 0.34 11.4 1.8 27 5.2 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Ribosomal_L29 PF00831.23 PFH31492.1 - 6.6e-20 70.8 1.0 6.6e-20 70.8 1.0 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein TolA_bind_tri PF16331.5 PFH31492.1 - 0.056 13.5 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation Snapin_Pallidin PF14712.6 PFH31492.1 - 1.2 9.6 11.0 0.075 13.5 1.6 2.2 1 1 1 2 2 2 0 Snapin/Pallidin AP2 PF00847.20 PFH31493.1 - 0.091 13.0 0.1 0.26 11.5 0.1 1.8 1 0 0 1 1 1 0 AP2 domain DUF2183 PF09949.9 PFH31494.1 - 0.00015 22.1 0.0 0.00031 21.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) zf-UBP PF02148.19 PFH31495.1 - 1.6e-14 54.0 6.3 3.5e-14 52.9 6.3 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DEAD PF00270.29 PFH31496.1 - 4.5e-44 150.3 0.1 8.2e-44 149.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH31496.1 - 3.9e-31 107.7 0.4 3.4e-30 104.6 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH31496.1 - 4.4e-07 30.1 0.0 7.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PFH31496.1 - 0.00013 21.7 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 PFH31496.1 - 0.00036 20.4 0.0 0.0013 18.7 0.0 1.8 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.6 PFH31496.1 - 0.00042 20.7 0.3 0.0013 19.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain tRNA-synt_1b PF00579.25 PFH31496.1 - 0.00098 18.5 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) SWI2_SNF2 PF18766.1 PFH31496.1 - 0.0031 17.2 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase CMS1 PF14617.6 PFH31496.1 - 0.0045 16.4 0.3 0.015 14.6 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit CDC37_C PF08564.10 PFH31496.1 - 0.046 13.9 0.1 9.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Cdc37 C terminal domain PPR_2 PF13041.6 PFH31497.1 - 1.6e-52 175.5 0.0 3.2e-12 46.4 0.0 9.0 5 2 4 9 9 9 7 PPR repeat family PPR_1 PF12854.7 PFH31497.1 - 3e-37 126.0 5.8 0.00017 21.2 0.0 10.2 10 1 0 10 10 10 7 PPR repeat PPR_3 PF13812.6 PFH31497.1 - 4.7e-34 116.3 0.0 0.00029 20.8 0.0 7.5 7 0 0 7 7 7 7 Pentatricopeptide repeat domain PPR PF01535.20 PFH31497.1 - 8e-34 113.5 8.9 0.00012 22.0 0.0 12.2 13 0 0 13 13 13 6 PPR repeat PPR_long PF17177.4 PFH31497.1 - 5.6e-17 61.8 0.4 7.3e-06 25.5 0.2 4.5 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 PFH31497.1 - 0.0024 17.7 0.0 3.7 7.4 0.0 2.8 2 0 0 2 2 2 2 Mitochondrial ATPase expression TPR_14 PF13428.6 PFH31497.1 - 0.012 16.4 3.3 37 5.5 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat EMP70 PF02990.16 PFH31497.1 - 0.078 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 DUF2783 PF10932.8 PFH31497.1 - 0.11 12.2 0.3 0.31 10.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) tRNA_U5-meth_tr PF05958.11 PFH31499.1 - 6.1e-07 28.8 0.0 1.9e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase UPF0020 PF01170.18 PFH31499.1 - 0.013 15.2 0.1 0.032 13.9 0.1 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 PFH31499.1 - 0.032 14.0 0.1 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 PFH31499.1 - 0.075 13.8 0.1 0.61 10.8 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 PFH31499.1 - 0.085 12.4 0.0 6.3 6.4 0.0 3.0 3 0 0 3 3 3 0 RNA cap guanine-N2 methyltransferase Yip1 PF04893.17 PFH31500.1 - 4e-12 46.2 12.2 6.7e-12 45.5 12.2 1.3 1 1 0 1 1 1 1 Yip1 domain DUF2964 PF11177.8 PFH31500.1 - 0.055 13.7 0.3 0.11 12.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) DUF1282 PF06930.12 PFH31500.1 - 0.19 11.5 5.5 0.28 10.9 5.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Ribosomal_L30 PF00327.20 PFH31501.1 - 0.00053 19.8 0.0 0.0017 18.2 0.0 1.9 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e NUDIX_5 PF16705.5 PFH31501.1 - 0.00071 19.4 1.1 0.31 10.8 1.1 2.1 2 0 0 2 2 2 2 NUDIX, or N-terminal NPxY motif-rich, region of KRIT Erp_C PF06780.11 PFH31502.1 - 4.3 7.4 9.8 0.74 9.8 0.1 3.5 3 2 0 3 3 3 0 Erp protein C-terminus TPT PF03151.16 PFH31505.1 - 5e-16 58.9 12.1 1.3e-14 54.2 12.1 2.1 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PFH31505.1 - 0.00013 22.1 34.1 0.065 13.4 14.2 3.8 3 1 0 3 3 3 3 EamA-like transporter family Ion_trans PF00520.31 PFH31507.1 - 3.2e-18 65.9 22.0 4.2e-18 65.5 22.0 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 PFH31507.1 - 3.5e-05 22.7 14.0 5.1e-05 22.1 14.0 1.2 1 0 0 1 1 1 1 Polycystin cation channel DUF4199 PF13858.6 PFH31507.1 - 0.0085 16.5 0.7 0.0085 16.5 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) CDC45 PF02724.14 PFH31507.1 - 5.8 5.1 7.5 9.9 4.3 7.5 1.3 1 0 0 1 1 1 0 CDC45-like protein CPSF_A PF03178.15 PFH31508.1 - 2.2e-32 112.6 0.0 5.4e-24 85.1 0.0 2.4 2 0 0 2 2 2 2 CPSF A subunit region MMS1_N PF10433.9 PFH31508.1 - 1.2e-26 93.4 0.0 4.6e-18 65.1 0.0 2.4 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term hSac2 PF12456.8 PFH31508.1 - 0.031 14.0 0.1 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 Inositol phosphatase EGF_CA PF07645.15 PFH31511.1 - 1.9e-207 671.3 542.3 7.6e-11 42.0 6.3 33.2 31 2 2 33 33 33 28 Calcium-binding EGF domain EGF_3 PF12947.7 PFH31511.1 - 5.2e-149 484.1 520.4 1.4e-09 38.0 11.7 32.8 32 0 0 32 32 32 30 EGF domain cEGF PF12662.7 PFH31511.1 - 9.9e-139 450.6 316.3 4.5e-09 36.1 3.9 31.9 31 0 0 31 31 31 27 Complement Clr-like EGF-like EGF PF00008.27 PFH31511.1 - 5.6e-63 208.8 427.0 0.00023 21.4 7.7 32.3 31 0 0 31 31 31 26 EGF-like domain EGF_MSP1_1 PF12946.7 PFH31511.1 - 4.9e-62 205.7 381.8 1.7e-06 27.9 3.6 32.0 31 0 0 31 31 31 28 MSP1 EGF domain 1 hEGF PF12661.7 PFH31511.1 - 2.8e-59 195.9 354.7 0.00048 20.7 4.4 34.1 32 0 0 32 32 32 28 Human growth factor-like EGF FXa_inhibition PF14670.6 PFH31511.1 - 5.3e-33 113.0 483.3 0.0003 21.0 8.9 32.3 27 3 5 32 32 32 23 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 PFH31511.1 - 3.4e-24 84.9 412.8 0.01 16.1 6.0 32.4 31 2 1 32 32 32 22 Pvs28 EGF domain Pkinase PF00069.25 PFH31513.1 - 1e-46 159.5 0.0 1.6e-16 60.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31513.1 - 1.9e-23 83.1 0.0 4.5e-19 68.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_7 PF13499.6 PFH31513.1 - 2.1e-09 37.7 0.1 0.46 11.0 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 PFH31513.1 - 3.6e-09 35.8 1.3 0.39 10.8 0.2 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 PFH31513.1 - 5.6e-09 34.9 8.7 0.00043 19.6 0.2 4.5 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 PFH31513.1 - 1.7e-05 24.5 6.3 0.32 10.9 0.2 4.3 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 PFH31513.1 - 0.0021 17.5 12.8 0.0079 15.6 0.4 4.0 4 0 0 4 4 4 2 EF hand Kinase-like PF14531.6 PFH31513.1 - 0.15 11.3 0.0 7.1 5.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Host_attach PF10116.9 PFH31513.1 - 9.2 6.8 7.0 4.8 7.7 0.0 2.7 2 0 0 2 2 2 0 Protein required for attachment to host cells tRNA-synt_1 PF00133.22 PFH31514.1 - 1.4e-40 139.1 0.4 7e-16 57.6 0.2 3.9 2 2 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PFH31514.1 - 6.1e-19 68.0 0.4 5.4e-08 32.0 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 PFH31514.1 - 3.2e-15 56.4 0.0 7.8e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 PFH31514.1 - 9.1e-13 48.2 2.7 1.6e-12 47.4 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain DUF1959 PF09218.10 PFH31514.1 - 0.0051 16.9 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1959) E1_dh PF00676.20 PFH31515.1 - 3.1e-82 275.9 0.0 3.9e-82 275.6 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 PFH31515.1 - 0.023 13.9 0.0 0.049 12.8 0.0 1.6 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Acetyltransf_1 PF00583.25 PFH31515.1 - 0.16 12.2 0.0 0.6 10.4 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family TPP_enzyme_C PF02775.21 PFH31515.1 - 2.2 8.0 4.4 50 3.6 4.4 2.5 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Form_Nir_trans PF01226.17 PFH31516.1 - 2.2e-70 236.7 19.1 2.7e-70 236.4 19.1 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter MORN PF02493.20 PFH31517.1 - 1.4e-46 153.7 73.8 1.5e-06 27.8 1.9 9.8 10 0 0 10 10 10 9 MORN repeat DUF3048_C PF17479.2 PFH31517.1 - 0.56 10.6 10.2 3.4 8.1 0.4 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain Ribosomal_L13 PF00572.18 PFH31518.1 - 8.6e-08 32.5 0.3 1.3e-05 25.5 0.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 Pkinase PF00069.25 PFH31519.1 - 5.3e-58 196.5 0.0 6.9e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31519.1 - 3.7e-37 128.0 0.0 5.2e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH31519.1 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Rtf2 PF04641.12 PFH31520.1 - 8.7e-49 166.2 0.0 1.5e-48 165.5 0.0 1.3 1 1 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 PFH31520.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zinc_ribbon_2 PF13240.6 PFH31520.1 - 0.27 11.0 2.5 13 5.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Ank_2 PF12796.7 PFH31521.1 - 9e-19 67.9 0.0 2.3e-14 53.7 0.0 3.8 2 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PFH31521.1 - 1.6e-15 57.0 0.8 3.2e-06 27.3 0.0 4.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PFH31521.1 - 3.7e-15 56.1 0.1 3e-07 30.8 0.0 5.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH31521.1 - 2.7e-14 51.9 0.0 0.0011 19.3 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 PFH31521.1 - 6.7e-13 48.5 1.2 0.0016 18.8 0.0 5.7 5 1 0 5 5 5 2 Ankyrin repeat TPR_19 PF14559.6 PFH31521.1 - 3.6e-05 24.2 0.0 0.00012 22.5 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Pro-rich PF15240.6 PFH31521.1 - 0.0013 19.0 50.0 0.0036 17.6 50.0 1.7 1 0 0 1 1 1 1 Proline-rich TPR_8 PF13181.6 PFH31521.1 - 0.033 14.4 2.9 0.45 10.8 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 PFH31521.1 - 0.064 13.1 0.1 0.42 10.5 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH31521.1 - 0.14 12.4 0.7 0.35 11.1 0.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SET PF00856.28 PFH31521.1 - 0.18 12.2 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 SET domain TPR_14 PF13428.6 PFH31521.1 - 0.6 11.1 0.1 0.6 11.1 0.1 4.4 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 PFH31521.1 - 2.1 8.4 7.5 0.14 12.2 1.7 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Fcf1 PF04900.12 PFH31522.1 - 2.8e-20 72.6 0.0 5.2e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 Fcf1 PIN_9 PF18477.1 PFH31522.1 - 0.0045 17.3 0.0 2.2 8.6 0.0 2.6 2 0 0 2 2 2 2 PIN like domain RRM_1 PF00076.22 PFH31523.1 - 5.5e-30 103.0 0.1 1.5e-12 47.2 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 PFH31523.1 - 0.0048 16.3 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 Lsm interaction motif Rpn3_C PF08375.11 PFH31524.1 - 1.6e-21 76.5 3.8 4.9e-21 74.9 3.8 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 PFH31524.1 - 2.1e-19 70.0 0.5 5.4e-19 68.7 0.0 2.0 3 0 0 3 3 3 1 PCI domain LexA_DNA_bind PF01726.16 PFH31524.1 - 0.13 12.0 0.1 27 4.6 0.0 2.7 2 0 0 2 2 2 0 LexA DNA binding domain DUF4490 PF14892.6 PFH31525.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) zf-C3HC4_3 PF13920.6 PFH31526.1 - 7.1e-06 25.8 8.9 7.1e-06 25.8 8.9 4.5 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Med13_C PF06333.12 PFH31527.1 - 0.014 14.7 2.1 0.015 14.6 2.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain RIIa PF02197.17 PFH31529.1 - 5.9e-07 29.0 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit RNA_pol_Rbc25 PF08292.12 PFH31530.1 - 1.3e-24 86.9 0.0 1.9e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 PFH31530.1 - 3.3e-10 40.2 0.0 5.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 PFH31530.1 - 0.028 14.8 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain NAD_kinase PF01513.21 PFH31531.1 - 1.5e-05 24.3 0.0 0.13 11.4 0.0 2.3 2 0 0 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.24 PFH31531.1 - 0.0011 18.6 0.0 0.0026 17.4 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PD40 PF07676.12 PFH31531.1 - 0.16 11.9 0.1 1.5 8.8 0.2 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat TGT PF01702.18 PFH31532.1 - 4.7e-17 62.2 0.0 1.1e-15 57.6 0.0 2.8 2 1 0 2 2 2 1 Queuine tRNA-ribosyltransferase CECR6_TMEM121 PF14997.6 PFH31533.1 - 2.3e-10 40.6 3.3 2.3e-10 40.6 3.3 2.1 2 0 0 2 2 2 1 CECR6/TMEM121 family Astro_capsid_p PF12226.8 PFH31533.1 - 0.091 11.9 1.3 0.14 11.3 1.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein zf-RING_2 PF13639.6 PFH31536.1 - 1.8e-08 34.6 9.9 3.1e-08 33.8 9.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PFH31536.1 - 6.1e-07 29.6 7.8 1.1e-06 28.8 7.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PFH31536.1 - 3e-05 23.8 9.4 4.8e-05 23.1 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PFH31536.1 - 9.8e-05 22.3 4.1 0.0002 21.3 4.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 PFH31536.1 - 0.0025 17.6 10.8 0.0041 16.9 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Fibrillin_U_N PF18193.1 PFH31536.1 - 0.013 15.6 0.8 0.013 15.6 0.8 2.1 2 0 0 2 2 2 0 Fibrillin 1 unique N-terminal domain zf-RING_5 PF14634.6 PFH31536.1 - 0.023 14.6 9.5 0.044 13.8 9.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 PFH31536.1 - 0.032 14.0 9.9 0.063 13.0 9.9 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 PFH31536.1 - 0.25 11.2 7.7 0.44 10.4 7.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 PFH31536.1 - 0.37 11.0 8.5 0.62 10.2 8.5 1.4 1 0 0 1 1 1 0 RING-variant domain Baculo_IE-1 PF05290.11 PFH31536.1 - 0.41 10.6 3.1 0.72 9.8 3.1 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.6 PFH31536.1 - 0.45 10.6 9.9 0.87 9.7 9.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 PFH31536.1 - 0.47 10.1 6.9 0.85 9.3 6.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 PFH31536.1 - 2.4 8.2 10.0 0.53 10.2 5.0 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 PFH31536.1 - 4.9 7.5 7.5 9 6.7 7.5 1.4 1 0 0 1 1 1 0 RING-like domain CoA_binding_3 PF13727.6 PFH31536.1 - 6.1 6.8 6.4 0.36 10.8 0.6 1.9 2 0 0 2 2 1 0 CoA-binding domain FANCL_C PF11793.8 PFH31536.1 - 6.5 7.0 6.3 12 6.1 6.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain rve PF00665.26 PFH31537.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain DUF5323 PF17257.2 PFH31538.1 - 0.18 11.7 4.3 0.51 10.3 4.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5323) DUF4486 PF14858.6 PFH31541.1 - 9.9e-11 40.8 2.8 1.1e-10 40.6 1.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4486) YdaS_antitoxin PF15943.5 PFH31541.1 - 0.048 13.5 0.0 5.4 7.0 0.0 2.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT NTP_transf_2 PF01909.23 PFH31544.1 - 6e-06 26.5 0.0 1.8e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 PFH31544.1 - 0.0061 16.7 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase Joubert PF15392.6 PFH31544.1 - 4.9 6.8 9.2 0.17 11.6 3.1 1.6 2 0 0 2 2 2 0 Joubert syndrome-associated DnaJ PF00226.31 PFH31545.1 - 7.7e-10 38.8 0.0 2.4e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Ank_5 PF13857.6 PFH31545.1 - 0.00032 20.9 0.0 0.00087 19.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH31545.1 - 0.22 12.2 0.1 0.94 10.3 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Fib_alpha PF08702.10 PFH31545.1 - 9.2 6.4 10.3 25 5.0 10.3 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family LapA_dom PF06305.11 PFH31546.1 - 0.0074 16.1 0.3 0.016 15.0 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Orthoreo_P10 PF07204.11 PFH31546.1 - 0.072 13.1 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 EVC2_like PF12297.8 PFH31546.1 - 0.086 11.5 0.1 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Syndecan PF01034.20 PFH31546.1 - 0.16 11.9 0.9 0.27 11.2 0.9 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 PFH31546.1 - 0.56 9.7 4.8 1 8.8 4.8 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3995 PF13160.6 PFH31547.1 - 0.0092 16.3 5.2 0.033 14.6 1.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3995) DUF1182 PF06681.13 PFH31547.1 - 0.01 15.4 1.2 0.01 15.4 1.2 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1182) DHHC PF01529.20 PFH31547.1 - 0.04 14.0 2.1 0.04 14.0 2.1 2.2 1 1 0 2 2 2 0 DHHC palmitoyltransferase DUF3290 PF11694.8 PFH31547.1 - 0.94 9.4 4.7 0.12 12.3 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) DUF4191 PF13829.6 PFH31547.1 - 2 7.7 5.5 0.15 11.4 0.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) HMG_box PF00505.19 PFH31548.1 - 4.5e-24 84.6 2.4 6.4e-24 84.2 2.4 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PFH31548.1 - 3.8e-18 65.8 1.5 5.2e-18 65.4 1.5 1.2 1 0 0 1 1 1 1 HMG-box domain KIAA1430 PF13879.6 PFH31548.1 - 0.041 14.6 0.2 0.054 14.3 0.2 1.2 1 0 0 1 1 1 0 KIAA1430 homologue Neuropep_like PF15161.6 PFH31550.1 - 0.072 12.8 0.4 0.99 9.1 0.0 2.4 2 0 0 2 2 2 0 Neuropeptide-like WD40 PF00400.32 PFH31551.1 - 2.7e-12 47.0 2.6 1.6e-05 25.6 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat baeRF_family10 PF18854.1 PFH31551.1 - 0.0066 16.7 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Solute_trans_a PF03619.16 PFH31552.1 - 3.3e-85 285.8 0.0 5.1e-85 285.2 0.0 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF5132 PF17195.4 PFH31555.1 - 0.0059 16.7 0.9 0.013 15.6 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF5132) SseB_C PF14581.6 PFH31555.1 - 0.13 12.3 0.0 4 7.6 0.0 2.8 3 0 0 3 3 3 0 SseB protein C-terminal domain DEAD PF00270.29 PFH31556.1 - 1.8e-43 148.3 0.0 3.6e-43 147.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH31556.1 - 3.8e-31 107.7 0.0 6.4e-30 103.7 0.0 2.9 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH31556.1 - 4.9e-06 26.7 0.0 4.1e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 PFH31556.1 - 0.006 16.6 2.5 0.006 16.6 2.5 1.8 2 0 0 2 2 2 1 Zinc knuckle SecA_DEAD PF07517.14 PFH31556.1 - 0.06 12.6 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain HEM4 PF02602.15 PFH31556.1 - 0.12 11.8 0.2 1 8.6 0.1 2.3 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD AAA_22 PF13401.6 PFH31556.1 - 0.17 12.2 0.3 8.7 6.6 0.0 3.1 4 1 0 4 4 4 0 AAA domain Abhydrolase_1 PF00561.20 PFH31557.1 - 0.0057 16.3 0.7 0.58 9.8 0.1 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PFH31557.1 - 0.05 12.9 0.0 6.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 SAG PF04092.13 PFH31558.1 - 7.1e-17 62.4 4.3 3.9e-09 37.4 3.0 2.3 2 0 0 2 2 2 2 SRS domain RCC1 PF00415.18 PFH31558.1 - 0.036 14.7 0.8 0.15 12.7 0.1 2.5 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat SAG PF04092.13 PFH31559.1 - 8.3e-18 65.4 0.4 5.7e-11 43.3 1.6 2.2 2 0 0 2 2 2 2 SRS domain DUF2845 PF11006.8 PFH31559.1 - 0.13 12.4 0.2 0.37 10.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2845) DOT1 PF08123.13 PFH31561.1 - 4.5e-06 26.3 0.0 7.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 zf-RING_UBOX PF13445.6 PFH31562.1 - 0.0033 17.4 3.4 0.012 15.7 3.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger OST-HTH PF12872.7 PFH31562.1 - 0.0034 17.2 0.0 0.0076 16.0 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain zf-RING_10 PF16685.5 PFH31562.1 - 0.79 9.9 9.6 0.056 13.6 3.7 2.2 3 0 0 3 3 3 0 zinc RING finger of MSL2 Pkinase PF00069.25 PFH31563.1 - 1.9e-52 178.2 0.0 2.3e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31563.1 - 9.3e-30 103.8 0.0 1.3e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH31563.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PFH31563.1 - 0.019 14.4 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2282 PF10048.9 PFH31564.1 - 0.49 10.4 3.1 0.83 9.7 0.1 3.0 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2282) PCP_red PF08369.10 PFH31564.1 - 1.8 8.9 8.6 0.63 10.3 1.2 3.3 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit NAD_Gly3P_dh_N PF01210.23 PFH31565.1 - 4.7e-44 150.1 0.0 8.7e-44 149.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 PFH31565.1 - 8.1e-42 142.9 0.0 1.7e-41 141.8 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus KfrA_N PF11740.8 PFH31565.1 - 0.65 10.7 4.8 0.91 10.2 3.0 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term T4SS PF07996.11 PFH31565.1 - 8.4 6.7 15.2 30 4.9 15.3 1.9 1 1 0 1 1 1 0 Type IV secretion system proteins Spc7 PF08317.11 PFH31566.1 - 0.36 9.7 11.9 0.62 8.9 11.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 PFH31566.1 - 0.76 9.1 13.0 1.4 8.2 13.0 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4127 PF13552.6 PFH31566.1 - 4.5 5.8 12.4 0.12 10.9 5.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4127) UPF0242 PF06785.11 PFH31566.1 - 6.6 6.8 12.4 12 6.0 12.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus S4 PF01479.25 PFH31568.1 - 1.3e-06 28.0 0.0 2.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain UDG PF03167.19 PFH31569.1 - 3.3e-20 72.6 0.0 6.1e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Pkinase PF00069.25 PFH31570.1 - 1e-57 195.6 0.0 1.2e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31570.1 - 4.1e-37 127.9 0.0 4.9e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH31570.1 - 0.00074 18.9 0.0 0.0016 17.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PFH31570.1 - 0.00077 18.3 0.0 0.00089 18.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PFH31570.1 - 0.0076 15.6 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH31570.1 - 0.0087 16.0 0.1 0.51 10.2 0.4 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family tRNA_synt_2f PF02092.17 PFH31570.1 - 0.027 13.4 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit OKR_DC_1 PF01276.20 PFH31570.1 - 0.078 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain EF_TS PF00889.19 PFH31572.1 - 1.6e-30 106.3 0.1 7.1e-18 65.0 0.0 3.2 3 0 0 3 3 3 3 Elongation factor TS UBA PF00627.31 PFH31572.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain ADK PF00406.22 PFH31574.1 - 1.5e-30 106.3 0.0 1.3e-14 54.5 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 PFH31574.1 - 4.4e-23 82.2 0.0 2.4e-10 41.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 PFH31574.1 - 0.0093 16.5 0.0 0.18 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 PFH31574.1 - 0.012 15.3 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase AAA_33 PF13671.6 PFH31574.1 - 0.013 15.6 0.1 0.19 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 PFH31574.1 - 0.024 14.9 0.1 2.2 8.5 0.1 2.5 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 PFH31574.1 - 0.029 14.7 0.0 0.066 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 PFH31574.1 - 0.034 13.8 0.0 0.17 11.6 0.0 2.1 2 1 0 2 2 2 0 Dephospho-CoA kinase Cytidylate_kin2 PF13189.6 PFH31574.1 - 0.058 13.5 0.0 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase-like family ABC_tran PF00005.27 PFH31574.1 - 0.061 13.8 0.0 0.21 12.1 0.0 1.8 1 1 1 2 2 2 0 ABC transporter AAA_28 PF13521.6 PFH31574.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 PFH31574.1 - 0.15 11.7 0.0 1.7 8.2 0.0 2.5 3 0 0 3 3 3 0 Thymidylate kinase RCC1 PF00415.18 PFH31575.1 - 2.4e-35 120.9 13.8 1.6e-09 38.2 0.0 7.2 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH31575.1 - 4.6e-32 109.2 24.3 2.9e-09 36.5 1.8 5.7 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat DUF368 PF04018.13 PFH31575.1 - 0.0082 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF368) DUF21 PF01595.20 PFH31577.1 - 3.4e-29 101.8 4.5 3.4e-29 101.8 1.7 2.1 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 PFH31577.1 - 0.016 15.7 0.1 12 6.4 0.0 2.6 2 0 0 2 2 2 0 CBS domain NAD_Gly3P_dh_N PF01210.23 PFH31578.1 - 8.7e-45 152.5 0.0 1.4e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 PFH31578.1 - 6.6e-42 143.2 0.0 1.6e-41 141.9 0.1 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus STIMATE PF12400.8 PFH31581.1 - 2.3e-33 115.4 5.2 3.5e-33 114.8 5.2 1.3 1 0 0 1 1 1 1 STIMATE family PRORP PF16953.5 PFH31582.1 - 8.8e-06 25.4 0.1 2.2 7.7 0.0 4.8 5 0 0 5 5 5 2 Protein-only RNase P RNase_Zc3h12a PF11977.8 PFH31582.1 - 0.015 15.1 0.0 0.099 12.4 0.0 2.0 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain DUF4192 PF13830.6 PFH31584.1 - 0.16 12.0 2.6 4.5 7.2 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4192) PP2C_2 PF13672.6 PFH31585.1 - 5.7e-07 29.4 0.4 1.7e-06 27.9 0.4 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PFH31585.1 - 4e-06 26.9 0.1 0.13 12.2 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) FlxA PF14282.6 PFH31586.1 - 0.095 12.7 1.7 0.18 11.8 1.7 1.5 1 0 0 1 1 1 0 FlxA-like protein Pkinase PF00069.25 PFH31588.1 - 1.8e-62 211.1 0.0 2.4e-62 210.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31588.1 - 5.4e-27 94.7 0.0 8.2e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH31588.1 - 6.3e-06 25.7 0.0 2.3e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PFH31588.1 - 0.0046 16.3 0.1 0.0089 15.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GBP PF02263.19 PFH31590.1 - 1.3e-22 80.3 0.0 8.7e-17 61.2 0.0 3.1 2 2 0 2 2 2 2 Guanylate-binding protein, N-terminal domain DIT1_PvcA PF05141.12 PFH31590.1 - 0.044 13.2 3.6 0.1 12.0 3.6 1.6 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein PRTase_2 PF15609.6 PFH31590.1 - 0.14 11.7 0.1 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase RRM_1 PF00076.22 PFH31591.1 - 4.9e-18 64.7 0.1 9.3e-18 63.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PFH31591.1 - 0.00031 20.3 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH31591.1 - 0.011 15.8 0.1 0.023 14.8 0.1 1.7 1 1 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 PFH31591.1 - 0.044 13.6 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif CS PF04969.16 PFH31592.1 - 3.6e-09 37.5 0.0 8.3e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 CS domain PfkB PF00294.24 PFH31593.1 - 1e-42 146.5 1.5 7.9e-26 91.1 0.1 3.2 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Importin_rep_4 PF18808.1 PFH31594.1 - 0.00034 20.8 3.9 0.0092 16.2 0.6 2.8 2 0 0 2 2 2 1 Importin repeat MMS19_N PF14500.6 PFH31594.1 - 0.0026 17.4 4.1 0.043 13.4 1.1 2.8 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II IBN_N PF03810.19 PFH31594.1 - 0.058 13.3 0.0 0.26 11.2 0.0 2.2 1 0 0 1 1 1 0 Importin-beta N-terminal domain Importin_rep_3 PF18806.1 PFH31594.1 - 0.097 12.7 0.0 31 4.7 0.0 3.8 3 0 0 3 3 3 0 Importin 13 repeat PSD5 PF07637.11 PFH31594.1 - 0.26 11.6 2.1 6.6 7.2 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1595) EF-hand_1 PF00036.32 PFH31595.1 - 1.8e-16 58.4 0.1 1e-05 24.7 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 PFH31595.1 - 6.4e-15 55.4 0.6 1.3e-07 32.0 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH31595.1 - 1.3e-11 43.5 0.1 2.7e-05 23.7 0.0 3.7 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 PFH31595.1 - 1.9e-11 42.9 0.3 0.00019 20.7 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PFH31595.1 - 1.4e-10 40.8 0.1 0.0036 17.1 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 PFH31595.1 - 1.1e-06 28.8 0.0 0.00077 19.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 PFH31595.1 - 0.0003 21.6 0.0 0.00039 21.2 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 PFH31595.1 - 0.001 19.3 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 PFH31595.1 - 0.0042 17.1 0.1 0.0073 16.3 0.1 1.4 1 1 0 1 1 1 1 Tellurite resistance protein TerB Transposase_24 PF03004.14 PFH31595.1 - 0.056 13.6 0.0 0.071 13.2 0.0 1.1 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Caleosin PF05042.13 PFH31595.1 - 0.094 12.6 0.0 5.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Caleosin related protein Dockerin_1 PF00404.18 PFH31595.1 - 0.19 11.9 0.4 0.93 9.7 0.0 2.2 2 1 1 3 3 3 0 Dockerin type I domain CAP_GLY PF01302.25 PFH31596.1 - 3.6e-12 46.1 0.1 8.2e-12 45.0 0.1 1.6 1 1 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 PFH31596.1 - 9.9e-10 38.8 0.0 1.5e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain YukD PF08817.10 PFH31596.1 - 0.023 15.4 0.0 0.05 14.3 0.0 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD CGI-121 PF08617.10 PFH31599.1 - 4e-20 72.6 0.0 4.4e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF2767 PF10965.8 PFH31599.1 - 0.14 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) HDOD PF08668.12 PFH31599.1 - 0.18 11.2 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 HDOD domain Trypan_PARP PF05887.11 PFH31601.1 - 0.013 15.4 8.9 0.013 15.4 8.9 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DREPP PF05558.12 PFH31601.1 - 0.015 15.2 10.7 0.015 15.2 10.7 1.5 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide Connexin PF00029.19 PFH31601.1 - 0.05 13.3 1.3 0.14 11.9 0.5 1.8 1 1 1 2 2 2 0 Connexin DUF3328 PF11807.8 PFH31601.1 - 0.064 13.0 0.1 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) SID-1_RNA_chan PF13965.6 PFH31601.1 - 0.1 11.0 0.1 0.12 10.8 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ETRAMP PF09716.10 PFH31601.1 - 0.26 11.4 1.1 0.7 10.0 0.2 2.2 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PAXIP1_C PF15364.6 PFH31601.1 - 3 8.2 9.6 1.5 9.1 4.5 2.1 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein UPF0542 PF15086.6 PFH31601.1 - 7.7 6.5 9.1 0.53 10.2 1.0 2.7 1 1 2 3 3 3 0 Uncharacterised protein family UPF0542 Oxysterol_BP PF01237.18 PFH31603.1 - 4.1e-102 341.8 0.1 1.4e-66 224.8 0.0 3.1 3 0 0 3 3 3 3 Oxysterol-binding protein EGF_2 PF07974.13 PFH31604.1 - 1.7e-21 76.3 265.6 2.8e-05 24.4 16.2 14.7 13 1 1 14 14 14 11 EGF-like domain AMA-1 PF02430.15 PFH31604.1 - 3.9e-16 59.1 4.3 2.7e-14 53.0 0.3 3.5 3 1 1 4 4 4 2 Apical membrane antigen 1 EGF PF00008.27 PFH31604.1 - 0.0049 17.2 10.9 0.0049 17.2 10.9 13.9 12 2 2 14 14 14 8 EGF-like domain hEGF PF12661.7 PFH31604.1 - 0.015 15.9 3.2 0.015 15.9 3.2 16.7 17 0 0 17 17 17 0 Human growth factor-like EGF RR_TM4-6 PF06459.12 PFH31605.1 - 1.8 8.3 5.1 2.6 7.8 5.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 PFH31605.1 - 4.3 6.0 4.5 5.8 5.6 4.5 1.2 1 0 0 1 1 1 0 Presenilin DEAD PF00270.29 PFH31606.1 - 4e-16 59.3 0.0 1.3e-15 57.6 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PFH31606.1 - 2.9e-06 27.4 0.0 7.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PFH31606.1 - 0.00087 19.6 0.2 0.0031 17.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PBC PF03792.13 PFH31606.1 - 0.017 14.9 0.4 0.059 13.1 0.4 1.9 1 0 0 1 1 1 0 PBC domain Gluconate_2-dh3 PF13618.6 PFH31606.1 - 0.02 15.1 1.2 0.21 11.8 0.0 3.1 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 SET PF00856.28 PFH31606.1 - 5.4 7.4 5.0 4.1 7.8 1.1 2.9 2 0 0 2 2 2 0 SET domain UCH PF00443.29 PFH31607.1 - 3.7e-35 121.7 0.1 5.7e-35 121.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 PFH31607.1 - 1.5e-10 41.2 8.6 3.2e-10 40.2 8.6 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 PFH31607.1 - 1.6e-05 24.7 0.6 8.9e-05 22.2 0.6 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2388 PF09498.10 PFH31607.1 - 0.00055 19.9 0.5 0.00055 19.9 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2388) zf-UBP_var PF17807.1 PFH31607.1 - 0.76 9.6 8.5 0.21 11.3 4.4 2.2 3 0 0 3 3 3 0 Variant UBP zinc finger Spo7 PF03907.13 PFH31608.1 - 0.11 12.0 1.0 0.15 11.5 1.0 1.3 1 1 0 1 1 1 0 Spo7-like protein DUF5527 PF17665.1 PFH31608.1 - 0.89 9.1 3.7 1.6 8.3 0.4 2.1 1 1 0 2 2 2 0 Family of unknown function (DUF5527) Aminotran_5 PF00266.19 PFH31609.1 - 1.3e-20 73.7 0.0 2.1e-14 53.3 0.0 3.3 2 1 0 2 2 2 2 Aminotransferase class-V ATP_bind_3 PF01171.20 PFH31609.1 - 8e-16 58.3 0.0 1.5e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 PP-loop family Csm1_N PF18504.1 PFH31609.1 - 0.19 12.1 1.1 0.41 11.0 1.1 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain Striatin PF08232.12 PFH31609.1 - 0.2 12.3 2.3 0.54 10.8 2.3 1.7 1 0 0 1 1 1 0 Striatin family EF-hand_7 PF13499.6 PFH31610.1 - 6.7e-07 29.7 0.7 9.1e-05 22.8 0.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH31610.1 - 0.0035 17.1 1.8 0.023 14.6 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 PFH31610.1 - 0.019 14.5 0.7 0.22 11.1 0.0 2.9 3 0 0 3 3 3 0 EF hand CLAG PF03805.13 PFH31611.1 - 4.2e-11 41.3 0.5 4.2e-11 41.3 0.5 1.6 2 0 0 2 2 2 1 Cytoadherence-linked asexual protein Pkinase PF00069.25 PFH31612.1 - 1.8e-11 43.9 0.0 5.3e-08 32.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 PFH31612.1 - 0.00028 20.3 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PFH31612.1 - 0.003 16.4 0.0 0.17 10.6 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase Pkinase_Tyr PF07714.17 PFH31612.1 - 0.0083 15.4 0.0 0.026 13.8 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase PDCD2_C PF04194.13 PFH31613.1 - 3.4e-26 92.4 9.2 1.6e-25 90.2 0.3 3.5 3 1 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain SDA1 PF05285.12 PFH31614.1 - 1.5e-60 205.5 53.1 1.5e-60 205.5 53.1 2.3 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 PFH31614.1 - 3.2e-07 30.6 2.6 0.00012 22.4 0.7 3.2 2 0 0 2 2 2 2 NUC130/3NT domain DUF2207 PF09972.9 PFH31614.1 - 2.8 6.6 4.4 5.8 5.6 0.1 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Methyltr_RsmB-F PF01189.17 PFH31615.1 - 5e-34 117.7 0.0 1.1e-22 80.7 0.0 3.2 2 1 1 3 3 3 3 16S rRNA methyltransferase RsmB/F AAA_6 PF12774.7 PFH31617.1 - 3.1e-128 427.3 0.0 3.4e-127 423.9 0.0 2.9 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 PFH31617.1 - 8.5e-115 384.5 4.6 8.5e-115 384.5 4.6 3.6 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 PFH31617.1 - 1.4e-114 383.3 7.7 1.4e-114 383.3 7.7 3.3 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 PFH31617.1 - 7.5e-71 237.8 0.3 7.5e-71 237.8 0.3 3.3 3 0 0 3 3 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 PFH31617.1 - 7.2e-62 209.1 0.0 3.8e-61 206.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PFH31617.1 - 3e-44 151.5 0.0 1.6e-43 149.1 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain MT PF12777.7 PFH31617.1 - 1.2e-34 119.9 9.3 2.5e-34 118.8 9.3 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 PFH31617.1 - 2e-33 115.5 0.0 2.5e-27 95.5 0.0 4.5 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 PFH31617.1 - 1.5e-29 102.5 2.4 2.9e-28 98.3 0.0 4.1 5 0 0 5 5 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 PFH31617.1 - 2.3e-29 102.2 0.0 7.9e-12 45.4 0.0 6.4 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 PFH31617.1 - 2e-27 96.0 0.0 4.3e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 PFH31617.1 - 6.5e-17 61.8 0.0 3.3e-16 59.5 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 PFH31617.1 - 8.1e-14 52.2 3.3 0.0018 18.7 0.0 5.5 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PFH31617.1 - 1.7e-08 34.8 12.9 0.0037 17.5 0.0 8.3 8 1 1 9 9 8 1 AAA domain AAA_16 PF13191.6 PFH31617.1 - 6.5e-08 33.1 12.9 1.8 8.9 0.0 8.7 9 0 0 9 9 7 3 AAA ATPase domain AAA_18 PF13238.6 PFH31617.1 - 1e-06 29.3 0.2 4.1 8.0 0.0 5.7 5 0 0 5 5 4 1 AAA domain AAA_33 PF13671.6 PFH31617.1 - 1.2e-05 25.5 3.1 0.38 10.9 0.0 6.0 6 0 0 6 6 5 1 AAA domain T2SSE PF00437.20 PFH31617.1 - 5.5e-05 22.4 0.0 0.4 9.7 0.0 3.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_25 PF13481.6 PFH31617.1 - 5.6e-05 22.8 0.5 0.012 15.1 0.0 4.3 4 0 0 4 4 4 1 AAA domain Rad17 PF03215.15 PFH31617.1 - 0.00021 21.3 3.1 13 5.6 0.0 5.7 7 0 0 7 7 6 0 Rad17 P-loop domain AAA_lid_1 PF17857.1 PFH31617.1 - 0.00081 19.6 0.4 0.0029 17.8 0.4 2.0 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 PFH31617.1 - 0.0017 18.2 0.1 1.7 8.4 0.0 4.7 5 0 0 5 5 5 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 PFH31617.1 - 0.0018 17.7 1.0 7.4 5.9 0.0 4.1 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 PFH31617.1 - 0.0031 17.2 0.0 3.7 7.4 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.27 PFH31617.1 - 0.011 16.2 0.7 24 5.4 0.0 4.7 4 0 0 4 4 3 0 ABC transporter AAA_19 PF13245.6 PFH31617.1 - 0.012 16.0 4.2 0.55 10.5 0.0 5.2 5 0 0 5 5 5 0 AAA domain Sigma54_activat PF00158.26 PFH31617.1 - 0.015 15.0 0.0 44 3.7 0.0 3.7 3 0 0 3 3 3 0 Sigma-54 interaction domain cobW PF02492.19 PFH31617.1 - 0.023 14.3 0.2 0.22 11.1 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 PFH31617.1 - 0.033 13.6 0.0 2 7.7 0.0 3.8 4 0 0 4 4 4 0 FtsK/SpoIIIE family TsaE PF02367.17 PFH31617.1 - 0.034 14.2 1.8 15 5.6 0.0 4.0 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 PFH31617.1 - 0.035 14.5 0.1 1.9e+02 2.5 0.0 4.5 4 0 0 4 4 4 0 RNA helicase RuvB_N PF05496.12 PFH31617.1 - 0.038 13.7 0.1 3.2 7.5 0.0 3.0 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 PFH31617.1 - 0.17 11.6 3.9 19 4.9 0.0 4.5 5 0 0 5 5 3 0 AAA domain zf-C4H2 PF10146.9 PFH31617.1 - 1.9 8.8 10.6 0.44 10.8 0.8 3.0 2 0 0 2 2 2 0 Zinc finger-containing protein Pkinase PF00069.25 PFH31618.1 - 2.2e-08 33.8 0.0 9.7e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 PFH31618.1 - 1.5e-05 24.5 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Rhodanese PF00581.20 PFH31619.1 - 1.8e-10 41.3 0.0 5e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain CRT10 PF08728.10 PFH31619.1 - 0.56 8.3 3.0 0.76 7.9 3.0 1.1 1 0 0 1 1 1 0 CRT10 LMBR1 PF04791.16 PFH31619.1 - 1.8 7.4 3.0 2.4 7.0 3.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein EB1 PF03271.17 PFH31621.1 - 3.9e-08 33.4 0.5 3.9e-08 33.4 0.5 1.6 2 0 0 2 2 2 1 EB1-like C-terminal motif Ribonuc_red_lgC PF02867.15 PFH31622.1 - 2.2e-186 620.5 0.0 2.9e-186 620.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 PFH31622.1 - 1.2e-21 76.4 0.0 3.6e-21 74.9 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 PFH31622.1 - 6.3e-11 42.7 0.0 1.4e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain Tam41_Mmp37 PF09139.11 PFH31623.1 - 0.019 14.5 1.3 0.074 12.5 0.4 2.0 2 0 0 2 2 2 0 Phosphatidate cytidylyltransferase, mitochondrial SET PF00856.28 PFH31624.1 - 2.7e-07 31.1 0.4 2.8e-06 27.8 0.0 2.8 2 0 0 2 2 2 1 SET domain eIF-3c_N PF05470.12 PFH31625.1 - 2.3e-122 409.3 24.5 1.1e-86 291.5 3.7 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 PFH31625.1 - 1.4e-13 51.2 0.8 9.8e-12 45.3 0.1 2.8 2 0 0 2 2 2 1 PCI domain RNA_pol_Rpb1_7 PF04990.12 PFH31625.1 - 0.026 14.5 0.3 0.12 12.4 0.3 2.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 BSP_II PF05432.11 PFH31625.1 - 6 6.5 28.1 1.5 8.4 20.5 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PH PF00169.29 PFH31626.1 - 6.9e-10 39.4 0.0 3e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 PH domain Peptidase_C92 PF05708.12 PFH31626.1 - 1.3e-09 38.3 0.0 2.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family PH_11 PF15413.6 PFH31626.1 - 1.5e-05 25.4 0.1 4.1e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 PFH31626.1 - 0.014 15.7 0.1 0.028 14.7 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.6 PFH31626.1 - 0.026 14.6 0.0 1 9.5 0.0 2.3 2 0 0 2 2 2 0 PH domain PDDEXK_6 PF04720.12 PFH31626.1 - 0.37 10.7 1.1 0.48 10.3 0.0 1.7 2 0 0 2 2 2 0 PDDEXK-like family of unknown function Ribonuc_red_lgC PF02867.15 PFH31627.1 - 3.9e-186 619.7 0.0 5.1e-186 619.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 PFH31627.1 - 1.6e-23 82.5 0.0 3.9e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 PFH31627.1 - 1.9e-11 44.4 0.0 4.1e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain RRM_1 PF00076.22 PFH31629.1 - 2.3e-18 65.8 0.0 6.4e-17 61.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 PFH31629.1 - 1.7e-13 51.0 1.9 4e-13 49.8 1.9 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_occluded PF16842.5 PFH31629.1 - 0.022 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Rhomboid PF01694.22 PFH31630.1 - 2.2e-24 86.2 14.8 2.2e-24 86.2 14.8 1.8 2 0 0 2 2 2 1 Rhomboid family Pan3_PK PF18101.1 PFH31631.1 - 2e-23 82.9 0.0 2.9e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain CLP1_P PF16575.5 PFH31632.1 - 3.7e-17 62.7 0.1 6.6e-11 42.3 0.0 3.3 3 0 0 3 3 3 3 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 PFH31632.1 - 1.9e-16 60.0 0.0 5.5e-16 58.6 0.0 1.7 2 0 0 2 2 2 1 N-terminal beta-sandwich domain of polyadenylation factor RRM_1 PF00076.22 PFH31633.1 - 2.1e-10 40.3 0.0 3.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.6 PFH31634.1 - 6.9e-08 32.2 7.4 8.7e-08 31.9 3.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PFH31634.1 - 1.3e-07 31.8 5.1 7.2e-07 29.4 2.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 PFH31634.1 - 3.1e-07 30.1 3.5 3.1e-07 30.1 3.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH31634.1 - 8e-07 28.9 2.3 8e-07 28.9 2.3 1.8 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PFH31634.1 - 1.5e-06 28.0 1.7 3.6e-06 26.7 1.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 PFH31634.1 - 1.6e-05 25.1 1.0 1.6e-05 25.1 1.0 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PFH31634.1 - 5.1e-05 23.1 2.4 5.1e-05 23.1 2.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH31634.1 - 0.0015 18.5 1.8 0.0015 18.5 1.8 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 PFH31634.1 - 0.0031 17.3 1.8 0.0072 16.1 1.8 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 PFH31634.1 - 0.0071 16.0 0.9 0.022 14.4 0.9 1.8 1 0 0 1 1 1 1 P-11 zinc finger Mustang PF15682.5 PFH31634.1 - 0.068 13.3 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 zf-RING_10 PF16685.5 PFH31634.1 - 0.084 13.0 3.4 0.18 12.0 3.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 PFH31634.1 - 0.15 12.2 0.6 0.3 11.2 0.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 PFH31634.1 - 0.27 11.4 3.6 0.91 9.7 3.6 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Sec16_C PF12931.7 PFH31635.1 - 1.2e-14 54.7 0.1 1.3e-13 51.2 0.1 2.1 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 DUF4487 PF14868.6 PFH31637.1 - 0.063 12.1 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) SOG2 PF10428.9 PFH31638.1 - 1.4 8.0 5.1 2 7.5 5.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 PFH31638.1 - 2.1 8.1 5.3 2.7 7.8 5.3 1.2 1 0 0 1 1 1 0 SPX domain Arm PF00514.23 PFH31639.1 - 3.9e-09 36.2 8.3 0.0038 17.2 0.0 5.6 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PFH31639.1 - 1e-05 25.8 1.2 0.0051 17.2 0.0 3.4 2 1 0 3 3 3 1 HEAT repeats V-ATPase_H_C PF11698.8 PFH31639.1 - 6.6e-05 23.0 0.0 0.0009 19.4 0.0 2.4 2 0 0 2 2 2 1 V-ATPase subunit H Arm_3 PF16186.5 PFH31639.1 - 0.008 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Atypical Arm repeat TPH PF13868.6 PFH31639.1 - 0.049 12.1 3.9 0.069 11.6 3.9 1.1 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain HEAT PF02985.22 PFH31639.1 - 0.051 13.9 5.5 40 4.9 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat THOC7 PF05615.13 PFH31640.1 - 1.2e-05 25.6 11.3 1.2e-05 25.6 11.3 1.9 1 1 1 2 2 2 1 Tho complex subunit 7 Fib_alpha PF08702.10 PFH31641.1 - 0.0062 16.7 0.7 0.01 16.0 0.7 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Tweety PF04906.13 PFH31641.1 - 0.16 10.6 0.1 0.21 10.2 0.1 1.1 1 0 0 1 1 1 0 Tweety GTP_EFTU PF00009.27 PFH31642.1 - 6.4e-54 182.5 0.0 1e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PFH31642.1 - 7.9e-41 138.9 0.2 1.9e-40 137.7 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PFH31642.1 - 2e-12 47.3 0.3 1.1e-11 45.0 0.3 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PFH31642.1 - 8.9e-05 22.5 0.0 0.0027 17.8 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FlpD PF02662.16 PFH31642.1 - 0.003 17.6 0.1 0.0093 16.0 0.0 1.8 2 0 0 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit Semialdhyde_dhC PF02774.18 PFH31642.1 - 0.051 13.6 0.3 0.18 11.8 0.1 2.0 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain ketoacyl-synt PF00109.26 PFH31643.1 - 0 1026.7 4.6 1.3e-81 273.9 0.2 4.8 4 0 0 4 4 4 4 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 PFH31643.1 - 1.4e-250 823.3 0.0 2.1e-63 213.5 0.0 4.9 5 0 0 5 5 4 4 KR domain PS-DH PF14765.6 PFH31643.1 - 5.1e-175 580.8 6.1 1.4e-48 165.7 0.1 5.9 6 0 0 6 6 6 5 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 PFH31643.1 - 5.8e-164 536.0 3.0 1.3e-40 138.0 0.1 4.6 4 0 0 4 4 4 4 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 PFH31643.1 - 4.7e-136 453.5 3.1 6.6e-51 173.7 0.1 3.4 3 0 0 3 3 3 3 Acyl transferase domain AMP-binding PF00501.28 PFH31643.1 - 1.1e-74 251.6 0.0 2.9e-74 250.2 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 PFH31643.1 - 1e-70 234.0 4.8 4.8e-15 55.7 0.1 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 PFH31643.1 - 4e-63 211.2 6.5 1.5e-15 57.4 0.1 5.7 6 0 0 6 6 5 4 Zinc-binding dehydrogenase adh_short PF00106.25 PFH31643.1 - 9e-61 204.7 0.7 5.8e-15 55.3 0.0 5.7 6 0 0 6 6 5 4 short chain dehydrogenase NAD_binding_4 PF07993.12 PFH31643.1 - 6.8e-58 195.8 0.0 1e-54 185.5 0.0 3.6 4 0 0 4 4 4 2 Male sterility protein adh_short_C2 PF13561.6 PFH31643.1 - 4.3e-42 144.3 0.1 1.5e-09 37.8 0.0 6.0 6 0 0 6 6 6 4 Enoyl-(Acyl carrier protein) reductase KAsynt_C_assoc PF16197.5 PFH31643.1 - 4.4e-41 139.9 0.2 1.4e-08 35.2 0.0 4.6 4 0 0 4 4 4 4 Ketoacyl-synthetase C-terminal extension Sulfotransfer_3 PF13469.6 PFH31643.1 - 8.5e-41 140.7 0.4 2.1e-40 139.4 0.4 1.7 1 0 0 1 1 1 1 Sulfotransferase family ADH_zinc_N_2 PF13602.6 PFH31643.1 - 7.4e-37 127.4 0.2 3.7e-08 34.5 0.0 5.0 4 0 0 4 4 4 4 Zinc-binding dehydrogenase Epimerase PF01370.21 PFH31643.1 - 5.2e-27 94.9 0.0 1.9e-09 37.3 0.0 5.5 5 0 0 5 5 5 5 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 PFH31643.1 - 1.1e-18 67.1 25.7 0.00013 21.8 0.1 7.6 9 0 0 9 9 9 4 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 PFH31643.1 - 2.4e-17 63.2 6.0 0.00037 19.9 0.1 4.5 4 0 0 4 4 4 4 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 PFH31643.1 - 4.3e-15 55.5 0.0 0.029 13.4 0.0 5.5 5 0 0 5 5 5 4 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 PFH31643.1 - 2.3e-13 49.9 0.0 0.058 12.5 0.0 5.3 5 0 0 5 5 5 3 Polysaccharide biosynthesis protein Sulfotransfer_1 PF00685.27 PFH31643.1 - 1.8e-07 31.0 0.0 8.2e-07 28.8 0.1 2.1 2 0 0 2 2 2 1 Sulfotransferase domain GDP_Man_Dehyd PF16363.5 PFH31643.1 - 1.8e-06 27.6 0.0 1.6 8.0 0.0 5.4 6 0 0 6 6 6 1 GDP-mannose 4,6 dehydratase YjeF_N PF03853.15 PFH31643.1 - 1.5e-05 25.0 0.8 11 5.9 0.0 5.1 5 0 0 5 5 4 0 YjeF-related protein N-terminus Sulfotransfer_4 PF17784.1 PFH31643.1 - 0.00061 19.7 0.7 0.0028 17.5 0.1 2.4 3 0 0 3 3 1 1 Sulfotransferase domain RPT PF13446.6 PFH31643.1 - 0.0014 18.5 0.3 9.3 6.3 0.0 4.3 4 0 0 4 4 4 0 A repeated domain in UCH-protein DUF1860 PF08949.10 PFH31643.1 - 0.023 14.4 5.8 2.3 7.9 0.0 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1860) Lysine_decarbox PF03641.14 PFH31643.1 - 0.025 14.7 0.0 0.088 12.9 0.0 1.9 1 0 0 1 1 1 0 Possible lysine decarboxylase ACP_syn_III_C PF08541.10 PFH31643.1 - 2.7 8.2 9.9 42 4.4 0.2 5.3 5 0 0 5 5 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AlaDh_PNT_C PF01262.21 PFH31643.1 - 4.8 6.4 15.3 1.1 8.5 0.2 4.6 5 0 0 5 5 5 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_32 PF13679.6 PFH31644.1 - 5.1e-11 42.8 1.7 4.5e-10 39.7 1.7 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH31644.1 - 1.2e-10 42.0 0.1 2.2e-09 37.9 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 PFH31644.1 - 2.1e-09 37.1 0.0 3.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PFH31644.1 - 1.2e-08 34.9 0.1 2.2e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PFH31644.1 - 1.1e-06 28.3 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 PFH31644.1 - 8.4e-06 26.5 0.0 2.9e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.15 PFH31644.1 - 0.00011 21.6 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_11 PF08241.12 PFH31644.1 - 0.00015 22.3 0.1 0.00072 20.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 PFH31644.1 - 0.0002 20.9 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 PFH31644.1 - 0.00052 19.4 0.0 0.00095 18.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Gag_p12 PF01141.18 PFH31644.1 - 0.015 15.6 0.2 5.3 7.5 0.1 3.0 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 Methyltransf_23 PF13489.6 PFH31644.1 - 0.041 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 PFH31644.1 - 0.053 13.5 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 PFH31644.1 - 0.23 11.2 0.0 0.41 10.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase zf-CCCH PF00642.24 PFH31645.1 - 2.5e-11 43.2 14.3 0.00012 21.9 0.6 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 PFH31645.1 - 0.045 14.4 19.3 0.38 11.5 1.2 4.0 2 1 2 4 4 4 0 Torus domain zf-CCCH_4 PF18044.1 PFH31645.1 - 0.051 13.4 0.3 0.051 13.4 0.3 3.5 3 0 0 3 3 3 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PFH31645.1 - 0.16 12.1 28.8 0.37 10.9 0.6 4.2 5 0 0 5 5 5 0 Zinc finger domain zf-CCCH_3 PF15663.5 PFH31645.1 - 1.5 9.0 12.2 5 7.4 7.9 2.4 1 1 1 2 2 2 0 Zinc-finger containing family Actin PF00022.19 PFH31646.1 - 7.2e-61 206.0 0.0 4.2e-59 200.2 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 PFH31646.1 - 0.005 15.7 0.0 0.0081 15.0 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DUF334 PF03904.13 PFH31647.1 - 0.047 13.2 1.1 0.08 12.5 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF2058 PF09831.9 PFH31647.1 - 0.81 9.8 4.4 2.8 8.1 4.4 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF4515 PF14988.6 PFH31647.1 - 7 6.4 11.5 6 6.6 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) Usp PF00582.26 PFH31648.1 - 1e-13 52.0 1.1 2.6e-12 47.4 0.5 2.5 2 0 0 2 2 2 1 Universal stress protein family OGG_N PF07934.12 PFH31649.1 - 9e-12 45.1 0.0 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 PFH31649.1 - 6.8e-06 26.5 0.1 0.00083 19.8 0.0 2.5 2 0 0 2 2 2 2 HhH-GPD superfamily base excision DNA repair protein HSP70 PF00012.20 PFH31651.1 - 1e-31 109.9 0.1 8.8e-18 63.8 0.0 3.4 2 1 0 3 3 3 3 Hsp70 protein TPR_9 PF13371.6 PFH31651.1 - 0.00028 21.0 1.1 0.00028 21.0 1.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PFH31651.1 - 0.015 15.3 3.6 0.4 10.8 0.2 3.5 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MetRS-N PF09635.10 PFH31651.1 - 0.05 14.1 1.3 9.9 6.7 0.3 3.2 2 1 0 2 2 2 0 MetRS-N binding domain TPR_1 PF00515.28 PFH31651.1 - 0.083 12.7 10.3 0.55 10.2 0.3 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 PFH31651.1 - 0.1 12.3 0.0 0.1 12.3 0.0 3.4 4 0 0 4 4 4 0 TPR repeat Ssl1 PF04056.14 PFH31654.1 - 9.1e-47 159.4 0.0 3.5e-34 118.3 0.0 2.2 2 0 0 2 2 2 2 Ssl1-like VWA_2 PF13519.6 PFH31654.1 - 4.1e-06 27.4 0.0 1.9e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 PFH31654.1 - 0.00026 21.1 12.3 0.00026 21.1 12.3 3.0 2 0 0 2 2 2 1 TFIIH C1-like domain Tfb4 PF03850.14 PFH31654.1 - 0.061 12.8 9.0 0.18 11.3 9.3 1.6 2 0 0 2 2 2 0 Transcription factor Tfb4 LRR_8 PF13855.6 PFH31655.1 - 2.4e-20 72.0 13.0 9.1e-08 31.8 1.1 4.7 4 0 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 PFH31655.1 - 5e-20 71.3 13.8 1e-06 29.0 0.7 5.6 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PFH31655.1 - 5.2e-14 52.1 2.0 2.7e-08 33.5 0.3 3.1 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 PFH31655.1 - 7.5e-06 25.6 21.3 2.7 8.2 1.0 7.4 7 1 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 PFH31655.1 - 0.0039 17.5 15.0 34 5.5 0.1 7.2 6 2 0 6 6 6 1 Leucine Rich Repeat TPR_10 PF13374.6 PFH31657.1 - 0.93 9.5 3.6 25 4.9 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec1 PF00995.23 PFH31660.1 - 3.1e-74 251.2 0.0 2.2e-48 165.9 0.0 2.7 2 1 0 2 2 2 2 Sec1 family HTH_40 PF14493.6 PFH31660.1 - 0.36 11.3 5.2 13 6.3 0.1 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain DEAD PF00270.29 PFH31661.1 - 8.6e-40 136.4 0.0 2e-39 135.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH31661.1 - 5.7e-22 78.2 0.0 3.1e-21 75.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH31661.1 - 0.0016 18.5 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PFH31661.1 - 0.036 14.3 0.3 0.22 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain LAP1C PF05609.12 PFH31661.1 - 4.4 6.3 11.4 7.7 5.5 11.4 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Patched PF02460.18 PFH31662.1 - 3e-108 363.0 0.2 3.5e-67 227.2 0.5 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 PFH31662.1 - 4.9e-31 107.6 4.8 4.9e-31 107.6 4.8 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 PFH31662.1 - 0.00036 18.4 4.6 0.00052 17.8 4.6 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family NDUF_C2 PF06374.11 PFH31664.1 - 0.086 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) HEAT PF02985.22 PFH31665.1 - 2.9e-13 48.8 14.1 0.00054 20.0 0.0 8.8 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.6 PFH31665.1 - 4.9e-12 46.1 16.4 5.6e-10 39.5 0.0 8.2 8 1 1 9 9 9 1 HEAT-like repeat HEAT_2 PF13646.6 PFH31665.1 - 6e-07 29.8 13.1 0.0014 19.0 0.0 6.3 5 1 1 6 6 6 2 HEAT repeats UME PF08064.13 PFH31665.1 - 0.0018 18.1 0.4 1.1 9.2 0.0 4.9 5 1 1 6 6 6 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 PFH31665.1 - 0.0095 16.5 0.0 5.8 7.6 0.1 3.8 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 PFH31665.1 - 0.018 15.1 0.8 0.51 10.4 0.1 3.7 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 PFH31665.1 - 0.042 13.8 0.0 0.33 10.9 0.0 2.7 1 0 0 1 1 1 0 Importin-beta N-terminal domain Arm PF00514.23 PFH31665.1 - 0.052 13.6 5.2 0.69 10.0 0.1 5.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat XRCC1_N PF01834.16 PFH31665.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 XRCC1 N terminal domain Dopey_N PF04118.14 PFH31665.1 - 0.069 12.3 0.3 7.2 5.6 0.1 3.1 3 0 0 3 3 3 0 Dopey, N-terminal HEAT_PBS PF03130.16 PFH31665.1 - 4.2 8.3 5.8 41 5.3 0.0 5.0 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat tRNA-synt_His PF13393.6 PFH31666.1 - 3.9e-09 36.2 0.1 0.11 11.7 0.0 4.7 5 0 0 5 5 5 4 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 PFH31666.1 - 0.18 11.8 0.0 0.52 10.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) CENP-R PF06729.12 PFH31666.1 - 0.33 10.9 1.1 12 5.8 0.1 2.3 2 0 0 2 2 2 0 Kinetochore component, CENP-R RNase_T PF00929.24 PFH31667.1 - 1.9e-07 31.7 0.0 4e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Exonuclease Presenilin PF01080.17 PFH31667.1 - 6.2 5.5 4.3 12 4.6 4.3 1.4 1 0 0 1 1 1 0 Presenilin Helicase_C PF00271.31 PFH31668.1 - 5.4e-11 42.8 0.0 2.4e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 PFH31668.1 - 4.8e-10 39.7 0.0 4.8e-10 39.7 0.0 4.0 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PFH31668.1 - 1.4e-09 38.2 0.0 4.3e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 PFH31668.1 - 0.0033 17.2 0.0 0.0099 15.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PFH31668.1 - 0.0051 17.1 0.1 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain PAP1 PF08601.10 PFH31668.1 - 2.2 7.9 15.8 5.8 6.5 15.8 1.7 1 0 0 1 1 1 0 Transcription factor PAP1 GREB1 PF15782.5 PFH31668.1 - 5 4.1 14.0 8.2 3.4 14.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TRAM_LAG1_CLN8 PF03798.16 PFH31669.1 - 7.9e-07 29.0 0.1 7.9e-07 29.0 0.1 2.8 3 0 0 3 3 3 1 TLC domain DUF1761 PF08570.10 PFH31669.1 - 0.032 14.5 0.4 0.43 10.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) OST3_OST6 PF04756.13 PFH31670.1 - 8.7e-24 84.4 0.0 8.5e-23 81.1 0.0 2.4 2 1 0 2 2 2 1 OST3 / OST6 family, transporter family PI3_PI4_kinase PF00454.27 PFH31673.1 - 3.2e-31 109.0 0.1 1.4e-22 80.8 0.1 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 PFH31673.1 - 8.1e-08 31.9 0.8 1.8e-07 30.7 0.8 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Kinase-like PF14531.6 PFH31674.1 - 5.6e-05 22.6 0.0 0.0012 18.2 0.0 2.0 1 1 1 2 2 2 2 Kinase-like Pkinase PF00069.25 PFH31674.1 - 0.042 13.2 0.0 3.7 6.8 0.0 2.1 1 1 1 2 2 2 0 Protein kinase domain UQ_con PF00179.26 PFH31676.1 - 1.6e-28 99.1 0.1 2.5e-28 98.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PFH31676.1 - 1.1e-05 25.1 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 PFH31676.1 - 0.00012 22.0 0.1 0.0002 21.2 0.1 1.3 1 0 0 1 1 1 1 UEV domain RepB-RCR_reg PF10723.9 PFH31678.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Replication regulatory protein RepB TPR_1 PF00515.28 PFH31679.1 - 3.1e-09 36.3 7.3 0.0046 16.7 0.0 6.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 PFH31679.1 - 1.1e-06 29.1 9.9 0.0041 17.7 0.0 4.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 PFH31679.1 - 8.9e-06 25.4 18.1 0.0013 18.7 0.0 6.7 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 PFH31679.1 - 0.00064 19.4 0.1 0.031 14.0 0.0 2.8 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 PFH31679.1 - 0.0063 17.2 14.9 3.9 8.5 0.4 5.5 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 PFH31679.1 - 0.012 16.2 4.8 2.7 8.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 PFH31679.1 - 0.017 14.8 0.4 0.91 9.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain CS PF04969.16 PFH31679.1 - 0.1 13.6 0.0 0.22 12.6 0.0 1.6 1 0 0 1 1 1 0 CS domain TPR_8 PF13181.6 PFH31679.1 - 0.12 12.6 7.4 6.1 7.3 0.1 5.6 8 0 0 8 8 6 0 Tetratricopeptide repeat TSP_NTD PF17804.1 PFH31679.1 - 0.23 11.7 4.9 0.86 9.8 5.1 1.8 2 0 0 2 2 2 0 Tail specific protease N-terminal domain TPR_12 PF13424.6 PFH31679.1 - 0.78 10.1 22.8 2.7 8.3 1.6 6.5 7 1 1 8 8 8 0 Tetratricopeptide repeat ClpS PF02617.17 PFH31680.1 - 1e-11 44.4 0.0 1e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS CDC45 PF02724.14 PFH31680.1 - 0.075 11.3 3.9 0.096 11.0 3.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3530 PF12048.8 PFH31680.1 - 0.11 11.8 3.1 0.16 11.4 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Peptidase_U57 PF05582.12 PFH31680.1 - 0.22 10.8 2.6 0.32 10.2 2.6 1.1 1 0 0 1 1 1 0 YabG peptidase U57 EFTUD2 PF16004.5 PFH31680.1 - 0.88 10.2 8.7 1.5 9.4 8.7 1.3 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Ycf1 PF05758.12 PFH31680.1 - 1.1 7.1 2.6 1.3 6.8 2.6 1.0 1 0 0 1 1 1 0 Ycf1 cNMP_binding PF00027.29 PFH31681.1 - 8e-09 35.5 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 PFH31682.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain PT-VENN PF04829.13 PFH31683.1 - 0.018 15.1 0.2 0.07 13.2 0.2 2.0 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Pkinase PF00069.25 PFH31684.1 - 1.2e-55 188.8 0.0 1.7e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31684.1 - 1.5e-22 80.1 0.0 2.5e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 PFH31684.1 - 4.7e-19 66.5 1.6 2e-06 27.0 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 PFH31684.1 - 3.9e-15 56.0 4.0 1.2e-08 35.2 0.6 3.1 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH31684.1 - 1.9e-14 52.3 5.8 0.0017 18.2 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 PFH31684.1 - 2.8e-12 45.5 1.0 0.0012 18.3 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PFH31684.1 - 8.8e-12 44.7 3.2 4.2e-07 29.7 0.4 4.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 PFH31684.1 - 0.00062 20.0 0.3 0.089 13.1 0.1 3.3 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 PFH31684.1 - 0.0071 16.6 0.2 0.37 11.1 0.1 2.6 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 PFH31684.1 - 0.037 14.9 0.0 8.1 7.4 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain CaMBD PF02888.16 PFH31685.1 - 3.5 7.9 11.6 0.14 12.4 4.6 2.3 2 0 0 2 2 2 0 Calmodulin binding domain TPR_1 PF00515.28 PFH31686.1 - 7.5e-06 25.5 1.0 0.0003 20.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 PFH31686.1 - 0.00026 20.9 4.8 0.0038 17.2 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 PFH31686.1 - 0.0016 18.7 0.1 0.34 11.4 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 PFH31686.1 - 0.016 14.9 0.2 0.062 13.0 0.1 2.0 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 PFH31686.1 - 0.036 14.9 1.4 0.59 11.1 0.1 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TAF4 PF05236.14 PFH31686.1 - 1.2 8.8 11.6 1.7 8.3 0.6 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Oxidored_molyb PF00174.19 PFH31687.1 - 3.7e-58 195.9 0.0 9.4e-58 194.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 PFH31687.1 - 7.8e-31 106.9 0.0 1e-22 80.6 0.0 2.6 2 0 0 2 2 2 2 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 PFH31687.1 - 6.1e-14 51.9 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HECT PF00632.25 PFH31688.1 - 3.3e-90 302.7 0.0 4.7e-90 302.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 PFH31688.1 - 2.2e-21 74.5 10.1 4.7e-08 32.2 2.4 4.4 3 0 0 3 3 3 3 Ubiquitin binding region DUF908 PF06012.12 PFH31688.1 - 2.8e-19 69.8 0.0 8.1e-12 45.2 0.0 7.0 8 1 0 8 8 8 2 Domain of Unknown Function (DUF908) DUF913 PF06025.12 PFH31688.1 - 5.6e-14 51.9 0.0 8.8e-09 34.8 0.0 7.9 6 1 0 6 6 6 2 Domain of Unknown Function (DUF913) UBA PF00627.31 PFH31688.1 - 4.9e-06 26.3 4.3 8.8e-05 22.3 0.4 2.8 2 0 0 2 2 2 1 UBA/TS-N domain CarS-like PF01864.17 PFH31688.1 - 0.37 10.8 0.6 1.4 8.9 0.4 1.9 2 0 0 2 2 2 0 CDP-archaeol synthase DUF4240 PF14024.6 PFH31690.1 - 0.017 15.3 0.1 4.7 7.4 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4240) Ubie_methyltran PF01209.18 PFH31691.1 - 2.7e-78 262.5 0.0 1.5e-54 184.8 0.0 3.5 2 1 1 3 3 3 3 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 PFH31691.1 - 2.7e-15 56.9 0.0 2.9e-08 34.3 0.0 4.0 4 0 0 4 4 4 3 Methyltransferase domain Methyltransf_11 PF08241.12 PFH31691.1 - 4e-15 56.2 0.0 2.6e-12 47.2 0.0 3.0 2 1 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH31691.1 - 5.2e-07 30.3 0.0 3.9e-05 24.3 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PFH31691.1 - 1.7e-06 27.9 0.0 0.0056 16.5 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 PFH31691.1 - 0.0002 21.3 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 PFH31691.1 - 0.013 15.4 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase WD40 PF00400.32 PFH31692.1 - 9.3e-26 89.6 22.2 9e-07 29.5 0.2 10.2 10 0 0 10 10 10 5 WD domain, G-beta repeat Utp12 PF04003.12 PFH31692.1 - 1.1e-15 57.8 2.3 2e-15 57.0 2.3 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 PFH31692.1 - 1.5e-12 47.7 0.2 0.036 14.4 0.0 6.9 5 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PFH31692.1 - 8.7e-05 21.6 0.3 1.4 7.8 0.1 3.7 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 PFH31692.1 - 0.0012 17.5 0.2 0.72 8.3 0.0 3.8 4 0 0 4 4 4 1 Cytochrome D1 heme domain Nup160 PF11715.8 PFH31692.1 - 0.019 13.7 0.4 6.2 5.3 0.3 3.6 3 1 1 4 4 4 0 Nucleoporin Nup120/160 PD40 PF07676.12 PFH31692.1 - 0.021 14.8 0.3 11 6.0 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat SGL PF08450.12 PFH31692.1 - 0.025 14.2 0.0 4.5 6.8 0.0 3.0 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Peptidase_M35 PF02102.15 PFH31694.1 - 0.00041 19.3 0.2 0.00055 18.9 0.2 1.2 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Het-C PF07217.11 PFH31694.1 - 0.023 13.2 1.1 0.028 12.9 1.1 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C TCTP PF00838.17 PFH31694.1 - 0.056 13.8 2.0 4.8 7.5 2.7 2.1 1 1 1 2 2 2 0 Translationally controlled tumour protein SICA_alpha PF12887.7 PFH31694.1 - 0.18 11.6 2.3 0.36 10.7 0.8 2.0 2 0 0 2 2 2 0 SICA extracellular alpha domain MT0933_antitox PF14013.6 PFH31694.1 - 0.22 11.9 1.7 5.3 7.4 0.0 2.5 2 0 0 2 2 2 0 MT0933-like antitoxin protein zf-UBR PF02207.20 PFH31695.1 - 2.1e-16 59.8 13.7 2.1e-16 59.8 13.7 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Peptidase_M13_N PF05649.13 PFH31699.1 - 2.4e-64 218.4 0.5 3.5e-64 217.9 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 PFH31699.1 - 1.8e-48 164.9 0.0 3.1e-24 85.7 0.0 2.5 2 0 0 2 2 2 2 Peptidase family M13 Peptidase_M48 PF01435.18 PFH31699.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M48 HABP4_PAI-RBP1 PF04774.15 PFH31699.1 - 1.7 9.5 8.2 0.35 11.7 2.6 2.4 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family SET PF00856.28 PFH31702.1 - 4.4e-19 69.5 0.7 2.4e-18 67.1 0.1 2.9 2 0 0 2 2 2 1 SET domain C2 PF00168.30 PFH31705.1 - 3.5e-33 114.0 0.3 2e-12 47.3 0.0 5.5 5 0 0 5 5 5 4 C2 domain RNase_H2_suC PF08615.11 PFH31705.1 - 0.19 11.9 0.2 0.59 10.3 0.2 1.8 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Got1 PF04178.12 PFH31707.1 - 4.1e-12 46.5 12.1 5.5e-12 46.1 12.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF373 PF04123.13 PFH31707.1 - 0.52 9.7 3.6 0.93 8.9 3.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Ctr PF04145.15 PFH31707.1 - 4.1 8.0 4.9 0.56 10.8 0.4 1.8 1 1 1 2 2 2 0 Ctr copper transporter family APG6_N PF17675.1 PFH31708.1 - 0.0018 18.8 8.6 0.0024 18.4 8.6 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region YbfN PF13982.6 PFH31708.1 - 0.0074 16.5 0.7 0.014 15.6 0.1 1.7 2 0 0 2 2 2 1 YbfN-like lipoprotein CorA PF01544.18 PFH31708.1 - 0.023 14.0 4.5 0.029 13.7 4.5 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PV-1 PF06637.11 PFH31708.1 - 0.072 11.9 5.9 0.081 11.7 5.9 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF3481 PF11980.8 PFH31708.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein DUF724 PF05266.14 PFH31708.1 - 0.26 11.1 6.5 0.34 10.7 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fmp27_WPPW PF10359.9 PFH31708.1 - 0.53 9.1 5.1 0.63 8.8 5.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Prominin PF05478.11 PFH31708.1 - 1.6 6.6 5.5 1.7 6.5 5.5 1.0 1 0 0 1 1 1 0 Prominin ADIP PF11559.8 PFH31711.1 - 0.023 14.8 0.9 0.66 10.0 0.1 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 PFH31711.1 - 0.47 10.5 2.4 5.9 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TAF6_C PF07571.13 PFH31712.1 - 6.2e-07 29.7 0.0 1.6e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 PFH31712.1 - 0.0016 18.6 0.1 0.0042 17.2 0.1 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) MINDY_DUB PF04424.13 PFH31713.1 - 3.9e-17 62.4 0.0 1.4e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 MINDY deubiquitinase HEAT_2 PF13646.6 PFH31716.1 - 1.3 9.4 6.2 0.38 11.2 1.3 2.8 2 0 0 2 2 2 0 HEAT repeats MPS2 PF17060.5 PFH31717.1 - 0.15 11.3 1.3 0.2 10.9 1.3 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 3-PAP PF12578.8 PFH31717.1 - 0.97 9.2 4.9 6.2 6.6 0.4 2.3 1 1 1 2 2 2 0 Myotubularin-associated protein SPATA3 PF15662.5 PFH31718.1 - 1e-05 26.3 32.9 0.01 16.5 16.0 2.5 1 1 1 2 2 2 2 Spermatogenesis-associated protein 3 family TetR_C_11 PF16859.5 PFH31718.1 - 0.42 11.0 0.1 0.42 11.0 0.1 2.4 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain NDK PF00334.19 PFH31719.1 - 2.2e-53 179.9 0.0 2.5e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase UBA PF00627.31 PFH31720.1 - 3.4e-27 93.9 7.8 8.5e-15 54.3 0.4 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 PFH31720.1 - 1.3e-22 79.3 11.9 2.4e-22 78.4 11.9 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 PFH31720.1 - 3.5e-15 55.5 0.0 5.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 PFH31720.1 - 1.1e-05 25.4 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RuvA_C PF07499.13 PFH31720.1 - 0.00015 22.1 0.1 0.8 10.2 0.0 3.0 2 0 0 2 2 2 2 RuvA, C-terminal domain DUF2407 PF10302.9 PFH31720.1 - 0.00062 20.3 0.0 0.001 19.6 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 PFH31720.1 - 0.028 14.3 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF3306 PF11748.8 PFH31720.1 - 0.63 10.9 12.7 2.9 8.8 12.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) Vps54 PF07928.12 PFH31721.1 - 2.9e-14 53.6 0.1 1.4e-13 51.4 0.1 2.1 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 PFH31721.1 - 5e-05 22.7 0.4 8.6e-05 22.0 0.4 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 PFH31721.1 - 0.023 14.8 0.5 0.049 13.7 0.5 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 NUC153 PF08159.12 PFH31722.1 - 0.0036 17.1 0.7 0.0066 16.2 0.7 1.4 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 PFH31722.1 - 0.0048 17.2 0.0 2 8.8 0.0 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Glyco_tran_WecB PF03808.13 PFH31722.1 - 0.14 12.1 0.0 0.47 10.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Synaphin PF05835.12 PFH31722.1 - 0.37 11.1 6.8 0.69 10.2 6.8 1.4 1 0 0 1 1 1 0 Synaphin protein TBCA PF02970.16 PFH31723.1 - 1.1e-20 73.7 2.7 1.1e-20 73.7 2.7 1.9 2 0 0 2 2 2 1 Tubulin binding cofactor A LRR_4 PF12799.7 PFH31724.1 - 1.9e-10 40.8 11.9 0.028 14.9 0.1 6.5 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH31724.1 - 2.6e-05 23.9 18.7 0.00037 20.2 2.1 5.4 5 1 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 PFH31724.1 - 0.099 12.7 6.8 65 4.0 0.0 5.7 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 PFH31724.1 - 1 10.1 15.8 72 4.5 0.0 7.4 7 0 0 7 7 7 0 Leucine Rich Repeat HAUS6_N PF14661.6 PFH31725.1 - 0.0044 16.6 1.4 0.0065 16.1 1.4 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus DUF725 PF05267.12 PFH31725.1 - 0.016 15.2 0.2 0.028 14.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF725) DUF5538 PF17692.1 PFH31726.1 - 0.02 15.0 0.8 0.025 14.6 0.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5538) DUF591 PF04569.14 PFH31726.1 - 0.052 13.6 2.6 0.1 12.7 2.5 1.6 1 1 0 1 1 1 0 Protein of unknown function Spc7 PF08317.11 PFH31727.1 - 2.6 6.8 41.2 0.0057 15.6 18.5 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF4559 PF15112.6 PFH31727.1 - 4.2 7.0 15.7 6.3 6.4 13.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Adap_comp_sub PF00928.21 PFH31729.1 - 4.3e-60 203.3 0.0 5.7e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 PFH31729.1 - 1.1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF572 PF04502.13 PFH31730.1 - 2.1e-64 218.2 12.2 3.1e-64 217.7 12.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf_Rg PF17915.1 PFH31730.1 - 0.06 12.7 0.1 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 Reverse gyrase zinc finger PI3K_1B_p101 PF10486.9 PFH31730.1 - 0.28 8.9 10.4 3.2 5.4 13.1 1.4 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit V_ATPase_I PF01496.19 PFH31730.1 - 2.4 6.0 8.0 3.2 5.6 8.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rubredoxin_2 PF18073.1 PFH31730.1 - 4 7.2 6.0 0.56 10.0 0.9 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain TPR_2 PF07719.17 PFH31731.1 - 3.2e-21 73.7 20.7 0.12 12.6 0.1 10.5 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 PFH31731.1 - 3.6e-20 70.9 2.6 0.073 12.9 0.0 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 PFH31731.1 - 1.4e-15 56.1 7.0 0.043 13.9 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 PFH31731.1 - 1.5e-15 56.0 7.6 0.091 13.0 0.0 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 PFH31731.1 - 3.4e-12 46.8 16.5 0.0025 18.4 0.0 7.2 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 PFH31731.1 - 2e-11 43.7 7.8 0.021 15.4 0.0 7.7 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 PFH31731.1 - 2.7e-11 43.6 22.5 0.00011 22.4 0.0 7.4 5 4 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 PFH31731.1 - 3e-11 43.2 17.6 0.022 15.5 0.0 9.1 6 3 3 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 PFH31731.1 - 1.1e-10 41.9 6.4 0.028 14.9 0.0 5.9 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 PFH31731.1 - 2.8e-08 33.3 1.6 1.2 8.8 0.1 6.1 6 1 1 7 7 7 2 TPR repeat TPR_MalT PF17874.1 PFH31731.1 - 5.5e-05 22.7 0.2 0.34 10.2 0.0 4.2 3 2 2 5 5 5 2 MalT-like TPR region ANAPC3 PF12895.7 PFH31731.1 - 5.7e-05 23.3 8.4 0.27 11.5 1.1 4.4 4 1 1 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 PFH31731.1 - 7.6e-05 22.1 1.2 0.093 11.9 0.5 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 PFH31731.1 - 0.00071 19.4 15.5 5.7 7.0 0.1 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_21 PF09976.9 PFH31731.1 - 0.0009 19.0 0.0 0.042 13.6 0.0 2.8 1 1 0 1 1 1 1 Tetratricopeptide repeat-like domain RPN7 PF10602.9 PFH31731.1 - 0.0013 18.5 0.4 9.3 5.9 0.0 4.5 2 2 3 5 5 5 1 26S proteasome subunit RPN7 TPR_9 PF13371.6 PFH31731.1 - 0.0053 16.9 10.2 0.33 11.1 0.1 5.2 4 2 3 7 7 7 1 Tetratricopeptide repeat MurB_C PF02873.16 PFH31731.1 - 0.079 13.0 0.0 0.69 10.0 0.0 2.4 2 0 0 2 2 2 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain DEAD PF00270.29 PFH31733.1 - 1.5e-44 151.8 0.0 2.8e-44 151.0 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH31733.1 - 2.8e-19 69.5 0.0 1.3e-18 67.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SPRY PF00622.28 PFH31733.1 - 8e-15 55.0 0.0 1.4e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 SPRY domain CMS1 PF14617.6 PFH31733.1 - 0.013 14.9 0.2 0.4 10.0 0.1 2.9 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 PFH31733.1 - 0.02 14.9 0.0 0.59 10.1 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PFH31733.1 - 0.31 11.3 0.8 0.91 9.8 0.0 2.1 2 1 1 3 3 3 0 AAA domain Ribosomal_S4e PF00900.20 PFH31734.1 - 5.2e-32 109.6 0.1 1.4e-31 108.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 PFH31734.1 - 2.5e-25 87.8 0.1 4.3e-25 87.1 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 PFH31734.1 - 2e-19 69.4 9.6 2e-19 69.4 9.6 2.3 3 0 0 3 3 3 1 RS4NT (NUC023) domain S4 PF01479.25 PFH31734.1 - 3.2e-05 23.5 0.1 6.4e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 PFH31734.1 - 0.00012 21.9 2.1 0.00012 21.9 2.1 2.2 2 0 0 2 2 2 1 KOW motif Sipho_tail PF05709.11 PFH31734.1 - 0.15 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Phage tail protein RtcB PF01139.17 PFH31735.1 - 2.8e-146 487.9 0.1 3.2e-146 487.7 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB ACP_syn_III_C PF08541.10 PFH31735.1 - 0.0069 16.5 0.0 0.024 14.8 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ras PF00071.22 PFH31736.1 - 2e-43 147.8 0.0 3.2e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH31736.1 - 6.6e-33 113.5 0.0 9.7e-33 112.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH31736.1 - 5.2e-12 45.6 0.0 6.5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PFH31736.1 - 2.8e-05 23.7 0.0 5.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PFH31736.1 - 0.0002 20.8 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ketoacyl-synt PF00109.26 PFH31736.1 - 0.0015 18.2 0.4 0.002 17.8 0.4 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain MMR_HSR1 PF01926.23 PFH31736.1 - 0.0021 18.1 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 PFH31736.1 - 0.0028 17.4 0.0 0.0055 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PFH31736.1 - 0.006 16.5 0.0 0.021 14.7 0.0 1.9 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 PFH31736.1 - 0.0061 17.1 0.0 0.0097 16.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PFH31736.1 - 0.04 14.3 0.2 0.075 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 PFH31736.1 - 0.09 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 PFH31736.1 - 0.13 12.5 0.1 1.2 9.4 0.0 2.2 1 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 PFH31736.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Hpr_kinase_C PF07475.12 PFH31736.1 - 0.2 11.1 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Ephrin_rec_like PF07699.13 PFH31737.1 - 1.3e-09 37.6 367.5 0.00079 19.1 4.6 35.0 25 8 9 37 37 37 24 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 PFH31738.1 - 0.00016 21.4 2.7 0.00016 21.4 2.7 7.5 3 2 5 8 8 8 5 Putative ephrin-receptor like DUF4080 PF13311.6 PFH31738.1 - 2.2 8.5 15.7 1.5 9.0 2.1 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4080) PP2C PF00481.21 PFH31739.1 - 3.5e-08 33.4 0.0 2.8e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PFH31739.1 - 0.0018 18.2 0.0 0.026 14.4 0.0 2.3 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 PFH31739.1 - 0.024 14.3 0.0 0.11 12.1 0.0 2.0 1 1 0 1 1 1 0 Protein phosphatase 2C Tubulin PF00091.25 PFH31740.1 - 2.8e-31 109.3 0.0 4.8e-22 79.1 0.0 2.9 2 1 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 PFH31740.1 - 0.00025 20.4 0.0 0.00043 19.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Kinase-like PF14531.6 PFH31741.1 - 1.4e-19 70.5 0.0 2e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH31741.1 - 7.9e-05 22.1 0.0 0.0002 20.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pyr_redox_2 PF07992.14 PFH31742.1 - 5.8e-47 160.3 0.0 8.1e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 PFH31742.1 - 2.3e-14 53.1 0.0 5.5e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 PFH31742.1 - 7.9e-11 42.4 0.1 7.9e-11 42.4 0.1 3.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 PFH31742.1 - 2.3e-09 37.7 0.0 1e-08 35.6 0.0 2.1 2 0 0 2 2 2 1 Reductase C-terminal Rieske_2 PF13806.6 PFH31742.1 - 6.8e-09 35.6 0.1 3.2e-08 33.4 0.0 2.2 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain Trp_halogenase PF04820.14 PFH31742.1 - 8e-05 21.7 0.3 0.14 11.0 0.0 2.4 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 PFH31742.1 - 0.00022 20.6 0.0 0.0075 15.6 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PFH31742.1 - 0.024 13.8 0.0 5.9 5.9 0.0 2.5 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 PFH31742.1 - 0.05 14.0 0.5 1.2 9.6 0.0 2.9 2 1 1 3 3 3 0 Putative NAD(P)-binding HI0933_like PF03486.14 PFH31742.1 - 0.055 12.2 1.8 0.36 9.5 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 PFH31742.1 - 0.058 13.0 6.3 0.12 11.9 0.0 3.2 2 1 0 4 4 4 0 FAD dependent oxidoreductase PCRF PF03462.18 PFH31743.1 - 1.8e-38 132.4 1.8 1.8e-38 132.4 1.8 2.8 3 1 0 3 3 3 1 PCRF domain RF-1 PF00472.20 PFH31743.1 - 1.9e-29 102.0 2.7 1.9e-29 102.0 2.7 3.2 4 0 0 4 4 4 1 RF-1 domain tRNA-synt_1 PF00133.22 PFH31744.1 - 5.1e-220 731.8 0.0 6.7e-220 731.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PFH31744.1 - 3.1e-24 85.7 0.0 9.8e-24 84.0 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PFH31744.1 - 1.9e-14 53.2 0.9 3.3e-06 26.1 0.3 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 PFH31744.1 - 0.0054 16.1 0.0 0.023 14.0 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain tRNA-Thr_ED PF08915.11 PFH31744.1 - 0.22 11.6 0.3 0.87 9.6 0.2 2.0 2 0 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase Kinesin PF00225.23 PFH31745.1 - 2e-116 388.5 0.0 3.6e-116 387.7 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PFH31745.1 - 3.6e-26 91.9 0.0 7.6e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 PFH31745.1 - 0.01 15.0 0.2 0.021 14.0 0.2 1.4 1 0 0 1 1 1 0 PIF1-like helicase Kinesin_assoc PF16183.5 PFH31745.1 - 0.94 9.6 10.9 4.3 7.4 10.9 2.1 1 0 0 1 1 1 0 Kinesin-associated ATG16 PF08614.11 PFH31745.1 - 1.5 9.0 35.9 2.6 8.2 9.5 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF1542 PF07564.11 PFH31745.1 - 4.4 7.5 6.6 3.6 7.8 4.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Skp1 PF01466.19 PFH31746.1 - 4.2e-25 87.6 0.3 7.8e-25 86.7 0.3 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 PFH31746.1 - 2.4e-20 72.5 1.5 5.5e-20 71.3 1.5 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 PFH31746.1 - 0.029 14.6 0.3 0.11 12.7 0.3 1.9 1 1 0 1 1 1 0 BTB/POZ domain GGA_N-GAT PF18308.1 PFH31746.1 - 0.085 12.5 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 GGA N-GAT domain dsDNA_bind PF01984.20 PFH31747.1 - 8.8e-24 83.9 10.7 1e-23 83.7 10.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Kinase-like PF14531.6 PFH31748.1 - 6.6e-10 38.8 0.0 1.7e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH31748.1 - 8.7e-06 25.3 0.0 5.7e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain CDP-OH_P_transf PF01066.21 PFH31749.1 - 3.6e-11 43.7 0.6 3.6e-11 43.7 0.6 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Nrap_D4 PF17405.2 PFH31750.1 - 3.4e-27 95.2 0.0 6.1e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 PFH31750.1 - 2.8e-24 85.9 0.0 8.1e-11 42.2 0.1 2.4 2 0 0 2 2 2 2 Nrap protein domain 1 Nrap_D3 PF17404.2 PFH31750.1 - 9.4e-18 64.8 0.0 3.3e-17 63.0 0.0 1.9 1 1 0 1 1 1 1 Nrap protein domain 3 Nrap_D5 PF17406.2 PFH31750.1 - 2.4e-12 46.9 0.0 2.9e-10 40.1 0.0 2.6 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 PFH31750.1 - 1.2e-09 38.1 0.0 4.1e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Nrap protein PAP/OAS-like domain FTA2 PF13095.6 PFH31751.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Cobl PF09469.10 PFH31751.1 - 0.19 12.0 0.0 0.51 10.6 0.0 1.7 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain Glyco_transf_17 PF04724.13 PFH31753.1 - 1.3e-16 60.6 0.2 1.5e-15 57.1 0.2 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 17 DnaJ_C PF01556.18 PFH31754.1 - 2.2e-32 112.2 0.0 3e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PFH31754.1 - 1.3e-19 70.1 0.3 1.3e-19 70.1 0.3 1.7 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 PFH31754.1 - 2.7e-09 37.2 16.4 8.1e-09 35.7 16.4 1.9 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 PFH31754.1 - 0.52 10.3 16.7 2 8.4 2.9 3.0 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein PCI PF01399.27 PFH31755.1 - 8.2e-10 39.1 0.0 2.7e-06 27.8 0.0 2.8 3 0 0 3 3 3 2 PCI domain SH3BP5 PF05276.14 PFH31755.1 - 0.55 10.0 5.7 2 8.1 0.0 2.5 2 1 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) LmjF365940-deam PF14421.6 PFH31755.1 - 3.6 7.1 5.7 0.48 10.0 1.5 1.6 2 0 0 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Enkurin PF13864.6 PFH31757.1 - 2.8e-20 72.6 0.1 3.5e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Calmodulin-binding Sin3_corepress PF08295.12 PFH31757.1 - 0.038 14.1 0.2 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Sin3 family co-repressor Mrpl_C PF18502.1 PFH31757.1 - 0.079 13.2 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain Pkinase PF00069.25 PFH31759.1 - 1.8e-60 204.6 0.2 4.3e-52 177.1 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31759.1 - 8.1e-28 97.4 0.1 1.2e-22 80.5 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 PFH31759.1 - 0.0033 16.3 1.2 1 8.1 1.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 PFH31759.1 - 0.019 13.9 0.3 0.049 12.6 0.3 1.7 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 PFH31759.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.5 3 1 0 3 3 3 0 Phosphotransferase enzyme family TFIIA PF03153.13 PFH31759.1 - 8.5 6.3 17.5 12 5.7 17.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MORN PF02493.20 PFH31760.1 - 1.6e-47 156.6 57.4 1.7e-07 30.7 0.1 10.6 11 0 0 11 11 11 10 MORN repeat Ribosomal_S17e PF00833.18 PFH31761.1 - 1.2e-57 193.1 0.9 1.4e-57 192.9 0.9 1.0 1 0 0 1 1 1 1 Ribosomal S17 NHL PF01436.21 PFH31762.1 - 3.1e-10 39.6 0.0 0.034 14.2 0.0 4.2 3 0 0 3 3 3 3 NHL repeat Ephrin_rec_like PF07699.13 PFH31762.1 - 0.00023 20.8 16.7 0.00047 19.9 5.6 49.4 35 13 13 50 50 50 28 Putative ephrin-receptor like SGL PF08450.12 PFH31762.1 - 0.014 15.0 0.0 0.061 12.9 0.0 2.0 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region TFIIB PF00382.19 PFH31763.1 - 3e-22 78.4 2.3 5.7e-10 39.1 0.1 2.9 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 PFH31763.1 - 5.9e-14 52.2 0.0 5.9e-14 52.2 0.0 3.1 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 PFH31763.1 - 2.9e-08 33.1 2.2 7.6e-08 31.8 2.2 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_24 PF13412.6 PFH31763.1 - 0.05 13.2 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Na_Ca_ex PF01699.24 PFH31764.1 - 1e-39 135.9 35.2 3.1e-20 72.7 15.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MIG-14_Wnt-bd PF06664.12 PFH31764.1 - 0.00022 20.5 2.2 0.00022 20.5 2.2 1.9 2 1 0 2 2 2 1 Wnt-binding factor required for Wnt secretion DUF3341 PF11821.8 PFH31764.1 - 0.071 12.7 1.1 6.6 6.4 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) MAP17 PF15807.5 PFH31764.1 - 1.6 9.0 4.4 3.1 8.0 4.4 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PBP PF01161.20 PFH31766.1 - 3.3e-14 53.3 0.0 5.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_S9 PF00380.19 PFH31767.1 - 1.8e-28 99.5 0.0 3e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF1712 PF08217.11 PFH31770.1 - 8.7e-27 93.9 0.0 3.4e-24 85.3 0.0 2.9 3 0 0 3 3 3 3 Fungal domain of unknown function (DUF1712) TRAP_alpha PF03896.16 PFH31770.1 - 0.63 9.2 2.0 1.4 8.1 2.0 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAD_binding_3 PF01494.19 PFH31771.1 - 2.5e-06 27.0 3.2 0.089 12.0 0.0 3.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 PFH31771.1 - 5.9e-06 26.1 0.0 8.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PFH31771.1 - 1.1e-05 24.7 0.0 2.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 PFH31771.1 - 0.00018 21.7 0.5 0.00047 20.3 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PFH31771.1 - 0.0016 17.7 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PFH31771.1 - 0.0025 17.0 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 PFH31771.1 - 0.0086 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 PFH31771.1 - 0.016 13.9 0.3 0.025 13.3 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 PFH31771.1 - 0.034 13.2 0.3 0.32 10.0 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 PFH31771.1 - 0.065 12.6 1.1 0.1 11.9 1.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 PFH31771.1 - 0.098 11.9 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HEAT_2 PF13646.6 PFH31772.1 - 0.058 13.8 18.6 1.3 9.5 1.0 5.6 6 1 0 6 6 6 0 HEAT repeats HEAT PF02985.22 PFH31772.1 - 0.07 13.4 20.0 0.089 13.1 0.2 6.7 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.6 PFH31772.1 - 1.1 9.9 22.3 0.1 13.1 0.5 5.9 5 0 0 5 5 5 0 HEAT-like repeat PIG-P PF08510.12 PFH31773.1 - 1.1e-26 93.1 0.3 1.7e-26 92.5 0.3 1.3 1 0 0 1 1 1 1 PIG-P FtsJ PF01728.19 PFH31774.1 - 7.1e-56 189.1 0.7 1.2e-55 188.4 0.1 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Spb1_C PF07780.12 PFH31774.1 - 1.4e-52 178.4 34.8 1.4e-52 178.4 34.8 4.1 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 PFH31774.1 - 5.8e-25 88.0 2.5 5.8e-25 88.0 2.5 5.7 4 2 2 6 6 6 1 Domain of unknown function (DUF3381) Use1 PF09753.9 PFH31775.1 - 1.2e-05 25.2 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Membrane fusion protein Use1 AP2 PF00847.20 PFH31777.1 - 3.1e-09 36.9 1.2 3.1e-09 36.9 1.2 2.2 2 0 0 2 2 2 1 AP2 domain PAN_1 PF00024.26 PFH31778.1 - 4.1e-49 164.4 81.5 3.1e-06 27.1 6.7 10.5 6 4 4 10 10 10 10 PAN domain PAN_4 PF14295.6 PFH31778.1 - 3.8e-37 126.0 56.1 4.2e-05 23.4 0.5 10.6 10 0 0 10 10 10 10 PAN domain DUF1770 PF08589.10 PFH31778.1 - 4.9e-08 33.9 47.4 5.1 8.1 0.2 10.6 9 1 0 9 9 9 8 Fungal protein of unknown function (DUF1770) HlyD_D4 PF16572.5 PFH31778.1 - 1.1e-05 25.2 7.8 1.2e+02 2.6 0.0 9.3 11 0 0 11 11 11 0 Long alpha hairpin domain of cation efflux system protein, CusB PAN_2 PF08276.11 PFH31778.1 - 0.69 10.1 67.4 4.5 7.5 0.3 11.3 10 1 1 11 11 11 0 PAN-like domain PAN_3 PF08277.12 PFH31778.1 - 4.2 7.2 55.9 0.65 9.9 0.8 10.0 10 0 0 10 10 10 0 PAN-like domain Aldo_ket_red PF00248.21 PFH31779.1 - 4.2e-59 200.2 0.0 6e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family ABC_membrane PF00664.23 PFH31780.1 - 5.6e-33 114.7 3.8 3.9e-22 79.2 0.6 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 PFH31780.1 - 1.7e-11 44.8 0.0 5.5e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 PFH31780.1 - 0.00049 20.7 0.0 0.00081 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PFH31780.1 - 0.0047 16.8 0.1 0.0082 16.1 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 PFH31780.1 - 0.033 13.9 0.1 0.07 12.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IPK PF03770.16 PFH31781.1 - 1.5e-50 171.8 0.0 2.3e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase 5-FTHF_cyc-lig PF01812.20 PFH31782.1 - 1.8e-20 73.6 0.0 2.1e-15 57.1 0.0 2.4 2 0 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family PHD PF00628.29 PFH31783.1 - 6.3e-11 42.0 14.6 1.2e-10 41.1 14.6 1.5 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 PFH31783.1 - 3.9e-06 27.4 0.9 5e-06 27.0 0.9 1.1 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD_2 PF13831.6 PFH31783.1 - 0.0016 18.0 6.3 0.0032 17.0 6.3 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 PFH31783.1 - 0.052 13.9 10.0 0.092 13.1 10.0 1.4 1 0 0 1 1 1 0 Ring finger domain PHF5 PF03660.14 PFH31783.1 - 0.11 12.7 4.3 0.18 12.0 4.3 1.3 1 0 0 1 1 1 0 PHF5-like protein zf-PHD-like PF15446.6 PFH31783.1 - 0.18 11.4 5.0 0.3 10.7 5.0 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain HscB_4_cys PF18256.1 PFH31783.1 - 0.95 9.3 6.9 0.82 9.5 0.3 3.8 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif PHD_4 PF16866.5 PFH31783.1 - 1.7 8.8 12.2 4.4 7.5 12.2 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 PFH31783.1 - 2.1 8.3 8.3 3.9 7.4 8.3 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Prok-RING_1 PF14446.6 PFH31783.1 - 3.9 7.5 11.5 3.5 7.6 6.7 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 PFH31783.1 - 6.8 6.9 9.3 19 5.5 9.3 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger zf-RRPl_C4 PF17026.5 PFH31783.1 - 8.4 6.6 8.0 2.2 8.4 3.6 2.1 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type CHCH PF06747.13 PFH31784.1 - 2.7e-05 24.2 5.4 3.2e-05 23.9 4.7 1.6 2 0 0 2 2 2 1 CHCH domain FHA PF00498.26 PFH31785.1 - 7.8e-07 29.4 0.0 1.6e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain DUF1192 PF06698.11 PFH31785.1 - 0.024 14.7 1.6 0.024 14.7 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF1993 PF09351.10 PFH31785.1 - 0.65 10.1 3.4 1.5 8.9 3.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) PNK3P PF08645.11 PFH31786.1 - 6.4e-41 139.8 0.0 3.9e-26 91.7 0.0 2.2 2 0 0 2 2 2 2 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 PFH31786.1 - 2.4e-13 50.5 0.3 3.1e-11 43.6 0.3 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PFH31786.1 - 5.9e-05 22.4 0.2 0.0014 17.9 0.0 2.2 1 1 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 PFH31786.1 - 0.0004 20.8 0.1 0.0012 19.3 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PFH31786.1 - 0.0026 18.0 0.0 0.0054 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 PFH31786.1 - 0.0038 17.7 0.0 0.0067 16.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 PFH31786.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KTI12 PF08433.10 PFH31786.1 - 0.017 14.6 3.3 0.42 10.0 0.1 2.2 1 1 1 2 2 2 0 Chromatin associated protein KTI12 Ploopntkinase3 PF18751.1 PFH31786.1 - 0.039 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 PFH31786.1 - 0.042 14.4 0.5 0.19 12.3 0.5 2.0 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 PFH31786.1 - 0.044 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 PFH31786.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PFH31786.1 - 0.069 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 PFH31786.1 - 0.096 12.4 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 PFH31786.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 PFH31786.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 PFH31786.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 PFH31786.1 - 0.15 12.5 0.1 0.39 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 PFH31786.1 - 0.18 11.9 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Glyco_trans_4_4 PF13579.6 PFH31786.1 - 0.68 10.4 5.0 4 7.8 0.2 3.5 3 1 1 4 4 4 0 Glycosyl transferase 4-like domain DUF2981 PF11200.8 PFH31787.1 - 1.4e-51 176.3 0.0 1.8e-51 175.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2981) PH PF00169.29 PFH31788.1 - 0.033 14.7 0.0 0.18 12.3 0.0 2.2 2 0 0 2 2 2 0 PH domain Hemocyanin_C PF03723.14 PFH31788.1 - 0.15 11.4 0.6 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 Hemocyanin, ig-like domain RRM_1 PF00076.22 PFH31789.1 - 5e-06 26.2 0.0 1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 PFH31789.1 - 0.15 12.3 0.2 0.15 12.3 0.2 2.7 2 1 1 3 3 3 0 CASC3/Barentsz eIF4AIII binding Seipin PF06775.14 PFH31790.1 - 6.9e-11 42.6 0.0 5.1e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Putative adipose-regulatory protein (Seipin) COG2 PF06148.11 PFH31791.1 - 0.0054 16.8 1.9 0.0054 16.8 1.9 6.9 5 3 3 8 8 8 1 COG (conserved oligomeric Golgi) complex component, COG2 ComC PF03047.14 PFH31791.1 - 0.062 13.1 0.7 0.49 10.2 0.2 2.6 2 0 0 2 2 2 0 COMC family HSBP1 PF06825.12 PFH31791.1 - 0.066 13.1 3.4 1.2 9.1 0.4 4.1 4 0 0 4 4 4 0 Heat shock factor binding protein 1 NPV_P10 PF05531.12 PFH31791.1 - 0.23 11.9 16.3 9.2 6.8 0.5 6.4 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF2935 PF11155.8 PFH31791.1 - 1.8 8.9 14.1 5 7.5 1.5 5.1 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) ApoO PF09769.9 PFH31791.1 - 4.4 7.3 6.1 3.8 7.5 0.0 3.6 4 0 0 4 4 4 0 Apolipoprotein O F-actin_cap_A PF01267.17 PFH31793.1 - 1.1e-17 64.4 0.0 8.2e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 F-actin capping protein alpha subunit SNF PF00209.18 PFH31795.1 - 2.9e-14 52.7 21.0 3.6e-12 45.8 21.0 2.2 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Herpes_US9 PF06072.11 PFH31795.1 - 1.2 9.0 7.1 0.56 10.1 0.2 2.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 SNF PF00209.18 PFH31796.1 - 1e-27 97.1 37.6 1e-27 97.1 37.6 2.0 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family Kazal_1 PF00050.21 PFH31797.1 - 2.2e-24 85.2 30.9 2.4e-09 37.0 2.1 4.5 3 1 0 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 PFH31797.1 - 7.2e-16 58.1 38.4 2.9e-05 24.1 6.0 5.6 5 1 0 5 5 5 5 Kazal-type serine protease inhibitor domain Antimicrobial21 PF14861.6 PFH31797.1 - 6.2 6.6 10.8 1.6 8.5 0.8 3.3 3 0 0 3 3 3 0 Plant antimicrobial peptide Kazal_1 PF00050.21 PFH31799.1 - 2.8e-15 56.1 29.7 3.6e-07 30.1 5.5 4.0 3 3 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 PFH31799.1 - 2.7e-09 37.0 30.8 2.8e-05 24.2 6.2 3.5 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain MMR_HSR1 PF01926.23 PFH31800.1 - 6.2e-16 58.5 0.2 2.6e-14 53.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PFH31800.1 - 2.8e-07 30.2 0.0 0.00011 21.8 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PFH31800.1 - 0.0002 21.3 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 PFH31800.1 - 0.014 15.5 0.4 0.014 15.5 0.4 3.2 3 1 1 4 4 4 0 Dynamin family TFIIA PF03153.13 PFH31800.1 - 0.091 12.7 33.1 0.0094 16.0 22.8 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PP2C PF00481.21 PFH31801.1 - 2.5e-52 178.1 0.2 1e-49 169.5 0.2 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PFH31801.1 - 0.035 14.0 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Herpes_DNAp_acc PF04929.12 PFH31801.1 - 3.2 6.6 5.6 7.4 5.4 5.6 1.5 1 0 0 1 1 1 0 Herpes DNA replication accessory factor NAPRTase_N PF17767.1 PFH31803.1 - 3.9e-36 124.2 0.0 9.1e-36 123.0 0.0 1.7 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 PFH31803.1 - 1.7e-32 112.1 0.0 3.1e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 PFH31803.1 - 1.1e-06 28.4 0.0 0.049 13.2 0.0 2.3 1 1 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family DEAD PF00270.29 PFH31804.1 - 1.7e-39 135.4 0.1 5.8e-39 133.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH31804.1 - 1.2e-24 86.7 0.0 4.7e-24 84.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PFH31804.1 - 3.3e-07 29.8 0.0 8.6e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DBP10CT PF08147.12 PFH31804.1 - 4.6e-06 26.8 7.6 4.6e-06 26.8 7.6 2.7 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ResIII PF04851.15 PFH31804.1 - 0.00024 21.1 0.0 0.00092 19.2 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SLED PF12140.8 PFH31804.1 - 0.25 11.8 0.6 4.3 7.9 0.1 2.5 2 0 0 2 2 2 0 SLED domain FUSC PF04632.12 PFH31805.1 - 0.03 12.9 2.8 0.048 12.2 2.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Mito_carr PF00153.27 PFH31806.1 - 1.3e-16 60.2 0.2 3.4e-05 23.7 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein UQ_con PF00179.26 PFH31807.1 - 1.9e-15 56.7 0.0 3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DNA_ligase_A_M PF01068.21 PFH31808.1 - 1e-51 175.5 0.0 4.3e-42 144.1 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 PFH31808.1 - 1e-31 110.6 1.5 1.7e-31 109.8 0.1 2.1 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 PFH31808.1 - 1.7e-21 76.7 0.0 5.4e-21 75.0 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region V-ATPase_H_C PF11698.8 PFH31809.1 - 3.7e-43 146.4 0.9 3.7e-43 146.4 0.9 2.0 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 PFH31809.1 - 5e-29 101.6 0.0 1.1e-28 100.5 0.0 1.5 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 PFH31809.1 - 0.0092 16.0 0.0 1.8 8.7 0.0 4.0 3 1 1 4 4 4 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 PFH31809.1 - 0.027 13.9 0.2 0.21 11.0 0.0 2.1 1 1 1 2 2 2 0 Armadillo-like LXG PF04740.12 PFH31809.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily HEAT_2 PF13646.6 PFH31809.1 - 0.51 10.8 3.2 15 6.1 0.0 3.6 3 1 1 4 4 4 0 HEAT repeats Endonuclease_NS PF01223.23 PFH31810.1 - 5.5e-31 108.1 0.0 1.7e-22 80.4 0.0 3.9 3 1 0 3 3 3 3 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 PFH31810.1 - 0.017 15.2 0.0 0.05 13.7 0.0 1.8 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease DSPc PF00782.20 PFH31811.1 - 2.1e-07 30.9 0.0 3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PFH31811.1 - 0.00013 21.6 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 PFH31811.1 - 0.00041 20.5 0.0 0.00069 19.8 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Ribosomal_L12_N PF16320.5 PFH31811.1 - 0.86 9.4 0.0 0.86 9.4 0.0 2.8 3 0 0 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain MAR_sialic_bdg PF10564.9 PFH31812.1 - 3.4e-21 75.1 15.2 2.2e-17 62.8 0.4 4.5 2 2 3 5 5 5 3 Sialic-acid binding micronemal adhesive repeat MAR_sialic_bdg PF10564.9 PFH31813.1 - 6.3e-51 170.4 25.1 9.5e-23 80.1 1.0 4.3 2 2 2 4 4 4 4 Sialic-acid binding micronemal adhesive repeat RWD PF05773.22 PFH31814.1 - 7.8e-14 51.9 0.5 7.8e-14 51.9 0.5 1.7 2 0 0 2 2 2 1 RWD domain MEIOC PF15189.6 PFH31814.1 - 0.092 12.4 0.7 0.18 11.4 0.7 1.4 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC DUF4286 PF14114.6 PFH31814.1 - 0.092 13.2 1.1 0.56 10.7 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4286) DFRP_C PF16543.5 PFH31814.1 - 2.4 8.7 11.5 0.068 13.7 1.7 2.6 1 1 1 2 2 2 0 DRG Family Regulatory Proteins, Tma46 Voldacs PF03517.13 PFH31814.1 - 7.8 6.6 13.2 1.2 9.3 6.7 2.3 2 1 0 2 2 2 0 Regulator of volume decrease after cellular swelling RXT2_N PF08595.11 PFH31814.1 - 9.4 6.2 8.5 5.1 7.1 1.5 2.7 3 0 0 3 3 3 0 RXT2-like, N-terminal cEGF PF12662.7 PFH31815.1 - 0.0022 17.9 6.8 1 9.3 0.6 4.5 4 0 0 4 4 4 2 Complement Clr-like EGF-like DUF2293 PF10056.9 PFH31815.1 - 0.05 13.9 0.2 23 5.3 0.0 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2293) UQ_con PF00179.26 PFH31817.1 - 7.9e-45 152.0 0.0 1e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mito_carr PF00153.27 PFH31818.1 - 1.5e-17 63.3 4.7 4.9e-07 29.6 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Pollen_allerg_2 PF01620.16 PFH31818.1 - 0.046 13.9 0.7 0.085 13.1 0.7 1.4 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) DUF4442 PF14539.6 PFH31819.1 - 0.11 12.7 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) DUF5583 PF17821.1 PFH31820.1 - 0.00015 21.7 0.8 0.00023 21.1 0.8 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5583) FXMRP1_C_core PF12235.8 PFH31820.1 - 1.3 9.7 17.2 1.8 9.2 17.2 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal DXP_synthase_N PF13292.6 PFH31821.1 - 3.3e-88 295.4 0.1 2.4e-74 250.0 0.0 2.5 3 0 0 3 3 3 2 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 PFH31821.1 - 9.6e-42 142.7 0.0 1.7e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PFH31821.1 - 8.2e-16 58.0 0.2 8.5e-15 54.7 0.0 2.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transketolase_N PF00456.21 PFH31821.1 - 7.2e-07 28.5 0.0 0.0054 15.7 0.0 2.3 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.20 PFH31821.1 - 0.0041 16.1 0.1 0.0076 15.2 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 PFH31821.1 - 0.028 14.2 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Helicase_C PF00271.31 PFH31823.1 - 2.7e-16 59.9 0.0 1.1e-15 58.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 PFH31823.1 - 4.5e-16 59.1 0.0 1.3e-14 54.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 PFH31823.1 - 4e-09 36.7 0.0 9.6e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PFH31823.1 - 4.8e-05 23.2 0.2 0.00033 20.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 PFH31823.1 - 0.025 14.6 0.3 0.52 10.3 0.0 2.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SecA_DEAD PF07517.14 PFH31823.1 - 0.087 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain RecG_wedge PF17191.4 PFH31823.1 - 0.19 11.4 0.0 4.9 6.8 0.0 2.7 3 0 0 3 3 3 0 RecG wedge domain RRM_1 PF00076.22 PFH31825.1 - 7e-07 29.0 0.0 3.4e-05 23.6 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 PFH31826.1 - 2.6e-15 56.2 0.2 9.9e-15 54.4 0.2 2.1 1 0 0 1 1 1 1 G-patch domain HECT PF00632.25 PFH31827.1 - 3.2e-44 151.6 0.0 4.6e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_5 PF13857.6 PFH31827.1 - 1.3e-09 38.1 0.5 4.6e-05 23.6 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PFH31827.1 - 1.1e-08 35.5 0.1 0.031 14.9 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PFH31827.1 - 3.1e-07 30.9 0.0 1.5e-05 25.5 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 PFH31827.1 - 1.1e-05 25.6 0.0 0.081 13.4 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 PFH31827.1 - 1.8e-05 24.7 0.1 1.9 9.3 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat EF_TS PF00889.19 PFH31829.1 - 8.1e-26 90.9 2.2 1.4e-14 54.3 0.8 3.6 3 1 0 3 3 3 3 Elongation factor TS RIFIN PF02009.16 PFH31829.1 - 0.022 14.7 1.2 0.048 13.5 1.2 1.5 1 0 0 1 1 1 0 Rifin UBA_4 PF14555.6 PFH31829.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain TruB_C PF09142.11 PFH31829.1 - 0.4 10.5 10.8 0.047 13.5 2.4 3.2 3 0 0 3 3 3 0 tRNA Pseudouridine synthase II, C terminal T2SSM PF04612.12 PFH31830.1 - 0.087 12.9 1.8 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Usp PF00582.26 PFH31831.1 - 0.013 16.0 0.1 0.015 15.8 0.1 1.2 1 0 0 1 1 1 0 Universal stress protein family MRI PF15325.6 PFH31831.1 - 0.19 12.8 2.6 0.16 13.1 1.0 1.6 1 1 1 2 2 2 0 Modulator of retrovirus infection Actin PF00022.19 PFH31832.1 - 2.3e-145 484.3 0.0 9.2e-145 482.3 0.0 1.7 1 1 0 1 1 1 1 Actin DUF4201 PF13870.6 PFH31833.1 - 2e-29 102.6 32.3 5.6e-28 97.9 21.4 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4201) APG6_N PF17675.1 PFH31833.1 - 0.0003 21.3 6.1 0.0003 21.3 6.1 4.9 3 1 2 5 5 5 2 Apg6 coiled-coil region 23S_rRNA_IVP PF05635.11 PFH31833.1 - 0.019 15.3 0.8 0.21 11.9 0.1 2.5 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein LRRC37AB_C PF14914.6 PFH31833.1 - 0.02 14.8 1.5 0.074 13.0 1.5 1.9 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Cep57_CLD_2 PF14197.6 PFH31833.1 - 0.035 14.2 0.4 0.035 14.2 0.4 5.3 4 2 1 5 5 5 0 Centrosome localisation domain of PPC89 EFP PF01132.20 PFH31833.1 - 0.26 11.4 3.5 3.8 7.6 0.1 2.6 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain Occludin_ELL PF07303.13 PFH31833.1 - 0.51 11.1 13.7 0.067 13.9 1.9 3.5 3 1 0 3 3 3 0 Occludin homology domain Fez1 PF06818.15 PFH31833.1 - 2.3 8.6 32.9 1.5 9.2 8.8 3.3 1 1 2 3 3 3 0 Fez1 VEK-30 PF12107.8 PFH31833.1 - 4.1 7.4 9.1 13 5.9 1.9 2.9 2 0 0 2 2 2 0 Plasminogen (Pg) ligand in fibrinolytic pathway bZIP_1 PF00170.21 PFH31833.1 - 9.4 6.4 22.4 0.94 9.6 0.7 4.5 4 1 0 4 4 4 0 bZIP transcription factor Ank_4 PF13637.6 PFH31834.1 - 0.00092 19.7 0.0 0.2 12.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PFH31834.1 - 0.017 15.4 0.1 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 PFH31834.1 - 0.032 14.7 0.1 0.12 12.9 0.1 2.0 2 0 0 2 2 2 0 Ankyrin repeat Pkinase PF00069.25 PFH31836.1 - 7.6e-50 169.7 0.0 1e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31836.1 - 9.5e-42 143.1 0.0 1.2e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH31836.1 - 0.00093 18.6 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PFH31836.1 - 0.0024 17.9 0.1 0.45 10.4 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 PFH31836.1 - 0.0043 16.7 0.0 0.0074 15.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 PFH31836.1 - 0.1 11.9 0.2 0.19 11.1 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TSP_1 PF00090.19 PFH31837.1 - 1.6e-26 92.3 74.5 1.5e-08 34.7 6.4 7.8 7 2 0 7 7 7 5 Thrombospondin type 1 domain PAN_1 PF00024.26 PFH31837.1 - 0.016 15.1 16.1 0.05 13.6 1.5 3.6 4 0 0 4 4 4 0 PAN domain PAN_4 PF14295.6 PFH31837.1 - 0.12 12.3 0.1 0.12 12.3 0.1 4.6 5 0 0 5 5 5 0 PAN domain FeS_assembly_P PF01883.19 PFH31838.1 - 0.009 16.2 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 2 Iron-sulfur cluster assembly protein TRAPP PF04051.16 PFH31839.1 - 9.1e-35 119.5 0.0 1.7e-34 118.6 0.0 1.4 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component DUF547 PF04784.14 PFH31839.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF547 Lantibiotic_a PF14867.6 PFH31839.1 - 0.32 10.8 2.7 0.21 11.4 0.7 1.7 2 0 0 2 2 2 0 Lantibiotic alpha UMP1 PF05348.11 PFH31840.1 - 9.4e-20 71.0 0.0 1.1e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 PUB PF09409.10 PFH31841.1 - 5.1e-14 52.0 0.0 1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 PFH31841.1 - 0.00033 20.8 0.0 0.00078 19.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain DCP1 PF06058.13 PFH31842.1 - 2.5e-30 104.8 0.1 3.4e-30 104.4 0.1 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family UPF0139 PF03669.13 PFH31843.1 - 3.1e-07 30.2 0.0 3.6e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) RCC1 PF00415.18 PFH31844.1 - 2.8e-59 197.6 22.7 4.9e-12 46.3 0.1 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH31844.1 - 1.1e-20 72.9 38.3 6.6e-05 22.6 0.8 6.9 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 PFH31844.1 - 0.027 14.5 0.5 0.85 9.7 0.2 3.4 4 0 0 4 4 4 0 Kelch motif ASF1_hist_chap PF04729.13 PFH31845.1 - 3.4e-62 209.0 0.0 4.7e-62 208.5 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF4620 PF15399.6 PFH31845.1 - 0.77 10.1 3.6 0.28 11.6 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4620) CCDC53 PF10152.9 PFH31845.1 - 4.7 7.6 6.5 5.7 7.4 0.5 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex FYDLN_acid PF09538.10 PFH31845.1 - 6.3 7.5 11.1 0.74 10.5 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Pyr_redox_2 PF07992.14 PFH31846.1 - 7.6e-38 130.4 0.0 1e-37 130.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PFH31846.1 - 1.1e-10 41.9 0.0 6.6e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PFH31846.1 - 0.053 13.8 0.0 54 4.1 0.0 3.8 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain NMT PF01233.19 PFH31847.1 - 1.7e-75 252.3 0.1 4e-75 251.0 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 PFH31847.1 - 8.1e-73 244.4 0.7 1.2e-72 243.8 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 PFH31847.1 - 1.1e-05 25.5 0.0 0.00019 21.5 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PFH31847.1 - 0.0049 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PFH31847.1 - 0.075 13.0 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CENP-Q PF13094.6 PFH31848.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit PAN_1 PF00024.26 PFH31849.1 - 1.2e-20 73.3 29.8 1.1e-06 28.5 2.1 5.1 2 2 3 5 5 5 4 PAN domain PAN_4 PF14295.6 PFH31849.1 - 6.6e-11 41.9 28.6 0.0061 16.4 0.7 5.0 3 1 1 4 4 4 4 PAN domain MANEC PF07502.14 PFH31849.1 - 0.002 18.4 27.5 0.012 15.9 1.4 4.8 3 1 2 5 5 5 2 MANEC domain PAN_1 PF00024.26 PFH31850.1 - 1.9e-20 72.6 34.8 9.9e-07 28.6 4.3 4.9 2 2 3 5 5 5 4 PAN domain PAN_4 PF14295.6 PFH31850.1 - 3.1e-11 43.0 28.7 0.0018 18.1 1.3 4.9 3 1 1 4 4 4 4 PAN domain MANEC PF07502.14 PFH31850.1 - 1.2e-05 25.5 30.7 0.0036 17.6 0.4 4.7 3 1 2 5 5 5 4 MANEC domain PAN_3 PF08277.12 PFH31850.1 - 0.054 13.3 22.3 0.097 12.5 0.3 4.5 4 0 0 4 4 4 0 PAN-like domain ABC_membrane PF00664.23 PFH31851.1 - 7.4e-31 107.8 0.0 1.3e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PFH31851.1 - 1.1e-24 87.5 0.1 4.2e-24 85.6 0.0 2.1 2 0 0 2 2 1 1 ABC transporter AAA_22 PF13401.6 PFH31851.1 - 2.8e-06 27.6 0.2 9.7e-06 25.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PFH31851.1 - 8.2e-05 22.4 1.6 0.00017 21.4 0.6 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PFH31851.1 - 0.00034 21.0 2.2 0.00034 21.0 2.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 PFH31851.1 - 0.00055 19.6 0.1 0.0014 18.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 PFH31851.1 - 0.00067 19.9 5.0 0.01 16.1 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 PFH31851.1 - 0.00073 19.2 0.1 0.004 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 PFH31851.1 - 0.0011 18.8 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 PFH31851.1 - 0.0023 17.8 0.0 0.09 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 PFH31851.1 - 0.003 18.1 1.1 0.034 14.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 PFH31851.1 - 0.0048 16.4 0.2 1.2 8.6 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 PFH31851.1 - 0.0051 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 PFH31851.1 - 0.0096 16.1 2.6 0.033 14.4 0.2 2.6 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 PFH31851.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 PFH31851.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_14 PF13173.6 PFH31851.1 - 0.022 14.8 0.0 0.057 13.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.23 PFH31851.1 - 0.025 14.6 0.0 0.095 12.8 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase PRK PF00485.18 PFH31851.1 - 0.036 13.8 0.1 0.077 12.7 0.1 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_ATPase PF09818.9 PFH31851.1 - 0.039 12.8 0.6 0.2 10.4 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 PFH31851.1 - 0.042 13.8 0.1 0.18 11.7 0.1 2.1 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 PFH31851.1 - 0.061 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase Rad17 PF03215.15 PFH31851.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain DUF87 PF01935.17 PFH31851.1 - 0.13 12.3 0.3 0.3 11.1 0.3 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain cobW PF02492.19 PFH31851.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 PFH31851.1 - 0.14 11.8 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 PFH31851.1 - 0.15 12.6 0.2 0.15 12.6 0.2 1.9 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 PFH31851.1 - 0.18 11.1 0.0 0.42 9.9 0.0 1.5 1 0 0 1 1 1 0 KaiC NTPase_1 PF03266.15 PFH31851.1 - 0.21 11.5 0.8 0.49 10.3 0.2 1.9 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 PFH31851.1 - 0.22 11.9 0.0 0.57 10.6 0.0 1.7 2 0 0 2 2 1 0 RNA helicase NB-ARC PF00931.22 PFH31851.1 - 0.24 10.6 0.4 1.5 7.9 0.1 2.2 2 1 0 2 2 2 0 NB-ARC domain dNK PF01712.19 PFH31851.1 - 0.25 11.2 0.6 0.84 9.4 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase p25-alpha PF05517.12 PFH31852.1 - 0.0019 18.4 1.5 0.21 11.7 0.0 3.3 3 0 0 3 3 3 1 p25-alpha Apt1 PF10351.9 PFH31852.1 - 3.7 6.3 11.4 1.9 7.2 4.2 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain KH_1 PF00013.29 PFH31854.1 - 4.3e-20 71.3 0.0 6e-07 29.2 0.0 4.9 5 0 0 5 5 5 3 KH domain KH_2 PF07650.17 PFH31854.1 - 0.0013 18.6 0.1 0.084 12.7 0.1 3.2 4 0 0 4 4 4 1 KH domain KH_4 PF13083.6 PFH31854.1 - 0.02 14.8 0.2 1.7 8.6 0.1 3.3 3 0 0 3 3 3 0 KH domain Methyltrans_RNA PF04452.14 PFH31857.1 - 9e-45 152.8 0.0 1e-25 90.4 0.0 2.1 2 0 0 2 2 2 2 RNA methyltransferase ProQ_C PF17516.2 PFH31857.1 - 0.078 12.4 0.4 0.16 11.4 0.4 1.5 1 0 0 1 1 1 0 ProQ C-terminal domain PAM2 PF07145.15 PFH31858.1 - 0.0053 16.4 2.8 0.0053 16.4 2.8 2.3 2 0 0 2 2 2 1 Ataxin-2 C-terminal region COX5B PF01215.19 PFH31859.1 - 1.2e-09 37.9 0.0 2.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb FAM76 PF16046.5 PFH31861.1 - 4.4e-16 59.1 39.3 4.4e-16 59.1 39.3 8.1 4 3 3 8 8 8 1 FAM76 protein DZR PF12773.7 PFH31861.1 - 9.6 6.3 29.9 3.2 7.9 7.2 3.6 1 1 2 3 3 3 0 Double zinc ribbon Ribosomal_S28e PF01200.18 PFH31862.1 - 5.5e-32 109.6 1.2 6e-32 109.4 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e WD40 PF00400.32 PFH31863.1 - 3e-10 40.5 10.0 0.00015 22.4 0.7 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH31863.1 - 1.6e-06 28.3 0.4 0.36 11.1 0.1 5.1 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S4 PF00163.19 PFH31865.1 - 8.9e-10 39.3 1.6 1.2e-09 38.9 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 PFH31865.1 - 8.8e-09 34.9 0.0 2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain TLD PF07534.16 PFH31867.1 - 8.7e-29 100.5 0.3 2.4e-26 92.6 0.1 2.3 2 0 0 2 2 2 2 TLD Cation_ATPase_N PF00690.26 PFH31867.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus COG5 PF10392.9 PFH31869.1 - 0.096 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 WD40 PF00400.32 PFH31874.1 - 3.2e-10 40.4 10.3 0.0012 19.6 0.3 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat FAST_1 PF06743.15 PFH31877.1 - 0.052 13.5 4.5 0.25 11.3 0.1 3.9 3 1 2 5 5 5 0 FAST kinase-like protein, subdomain 1 RNase_T PF00929.24 PFH31878.1 - 2.1e-10 41.4 0.0 3.4e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 PFH31878.1 - 0.0021 17.8 0.0 0.0051 16.5 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease UPF0020 PF01170.18 PFH31879.1 - 2.1e-14 53.6 0.0 8.6e-12 45.1 0.0 2.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.8 PFH31879.1 - 0.021 14.3 0.0 20 4.5 0.0 3.2 2 1 0 3 3 3 0 RRNA methyltransferase AviRa Peptidase_M55 PF04951.13 PFH31880.1 - 0.13 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 D-aminopeptidase Asp PF00026.23 PFH31884.1 - 6.5e-06 25.8 0.0 7.9e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Eapp_C PF10238.9 PFH31886.1 - 0.81 9.8 2.8 2.4 8.3 2.8 1.8 1 1 0 1 1 1 0 E2F-associated phosphoprotein Telomerase_RBD PF12009.8 PFH31887.1 - 1.7e-25 89.7 0.2 5.1e-25 88.1 0.2 1.8 1 1 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RRM_1 PF00076.22 PFH31889.1 - 1.4e-23 82.5 0.0 5.7e-11 42.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PFH31889.1 - 1.5e-05 24.6 0.0 0.058 13.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PFH31889.1 - 0.0011 18.8 0.0 0.63 9.9 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 PFH31889.1 - 0.014 15.2 0.0 0.036 13.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) PHM7_cyt PF14703.6 PFH31889.1 - 0.015 15.5 0.9 4 7.6 0.2 2.9 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Ribosomal_L28 PF00830.19 PFH31891.1 - 3.9e-16 59.0 1.5 3.9e-15 55.8 1.2 2.3 2 0 0 2 2 2 1 Ribosomal L28 family DUF4149 PF13664.6 PFH31892.1 - 6e-14 52.2 3.5 6e-14 52.2 3.5 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4149) DUF5427 PF10310.9 PFH31893.1 - 2.4 7.0 5.4 4.5 6.1 5.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Helicase_C_2 PF13307.6 PFH31896.1 - 1.9e-43 148.6 0.0 1.5e-42 145.7 0.0 2.4 1 1 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 PFH31896.1 - 9.5e-36 123.1 0.0 3.3e-34 118.0 0.0 2.3 1 1 0 1 1 1 1 DEAD_2 zf-C3HC4_3 PF13920.6 PFH31896.1 - 7.9e-06 25.6 6.4 7.9e-06 25.6 6.4 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PFH31896.1 - 1.8e-05 24.5 9.1 1.8e-05 24.5 9.1 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 PFH31896.1 - 3.3e-05 24.0 0.0 0.0037 17.3 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 PFH31896.1 - 0.00029 21.1 8.6 0.0011 19.3 8.6 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PFH31896.1 - 0.00051 19.8 7.7 0.0014 18.4 7.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 PFH31896.1 - 0.0018 18.1 0.0 0.029 14.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 PFH31896.1 - 0.0019 18.0 8.0 0.0045 16.8 8.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PFH31896.1 - 0.0025 17.7 6.5 0.007 16.3 6.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PFH31896.1 - 0.0055 16.7 5.9 0.013 15.5 5.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PFH31896.1 - 0.032 14.4 11.2 0.011 15.8 7.9 2.1 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PFH31896.1 - 0.038 14.3 4.9 0.14 12.5 4.9 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 PFH31896.1 - 0.055 13.3 6.8 0.21 11.4 6.8 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PhoH PF02562.16 PFH31896.1 - 0.059 12.8 0.0 8.5 5.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein DUF2614 PF11023.8 PFH31896.1 - 0.26 11.4 0.2 0.53 10.4 0.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-ANAPC11 PF12861.7 PFH31896.1 - 5.4 7.1 5.9 1.3 9.1 2.6 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Radical_SAM PF04055.21 PFH31897.1 - 1.5e-14 54.8 0.0 3.3e-14 53.6 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 PFH31897.1 - 0.00013 22.1 0.0 0.00029 21.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 PFH31897.1 - 0.0062 16.8 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain UCR_Fe-S_N PF10399.9 PFH31897.1 - 0.02 14.2 0.5 0.053 12.9 0.5 1.7 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Ribosomal_60s PF00428.19 PFH31897.1 - 4.2 8.0 10.6 35 5.1 0.9 3.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Form_Nir_trans PF01226.17 PFH31898.1 - 3.5e-70 236.0 16.0 4.2e-70 235.8 16.0 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter BatA PF07584.11 PFH31899.1 - 0.7 10.3 0.0 0.7 10.3 0.0 3.5 2 2 1 3 3 3 0 Aerotolerance regulator N-terminal Syntaxin PF00804.25 PFH31900.1 - 1.2e-26 93.7 12.2 1.2e-26 93.7 12.2 1.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 PFH31900.1 - 4.7e-11 42.5 1.9 4.7e-11 42.5 1.9 2.0 2 0 0 2 2 2 1 SNARE domain CTK3 PF12243.8 PFH31900.1 - 5.4e-05 23.2 1.8 8.1e-05 22.6 1.0 1.7 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 MCPsignal PF00015.21 PFH31900.1 - 0.0094 15.8 0.3 0.0094 15.8 0.3 3.2 2 2 2 4 4 4 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PBP1_TM PF14812.6 PFH31900.1 - 0.081 13.3 0.1 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DASH_Dam1 PF08653.10 PFH31900.1 - 0.22 11.4 4.4 2.5 8.0 0.2 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 DASH_Dad4 PF08650.10 PFH31900.1 - 0.26 11.3 3.8 7.3 6.6 0.0 3.5 3 0 0 3 3 3 0 DASH complex subunit Dad4 WXG100 PF06013.12 PFH31900.1 - 0.4 11.0 9.1 2.1 8.7 1.7 3.4 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF2408 PF10303.9 PFH31900.1 - 0.62 10.6 10.3 0.04 14.5 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Mit_KHE1 PF10173.9 PFH31900.1 - 4.2 7.4 7.0 16 5.5 0.0 2.8 2 1 0 2 2 2 0 Mitochondrial K+-H+ exchange-related EMP24_GP25L PF01105.24 PFH31900.1 - 6.6 6.6 9.7 0.83 9.6 2.3 2.7 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Synaptobrevin PF00957.21 PFH31900.1 - 9.3 6.1 8.1 1.5 8.7 3.4 2.2 2 1 0 2 2 2 0 Synaptobrevin LRR_6 PF13516.6 PFH31901.1 - 3.6e-13 48.4 6.0 0.012 15.6 0.0 5.7 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 PFH31901.1 - 0.00031 20.9 0.2 11 7.0 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.7 PFH31901.1 - 0.023 15.1 2.3 0.23 11.9 0.1 2.9 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) RRM_1 PF00076.22 PFH31903.1 - 8e-12 44.8 0.0 2e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP40_C PF05022.12 PFH31904.1 - 2.1e-23 82.9 3.4 2.1e-23 82.9 3.4 3.3 4 0 0 4 4 4 1 SRP40, C-terminal domain Neur_chan_memb PF02932.16 PFH31904.1 - 4.3 7.3 6.6 5.5 7.0 6.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 PFH31904.1 - 7.5 5.2 11.5 8.8 5.0 11.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 PFH31904.1 - 9.7 4.8 13.7 12 4.5 13.7 1.3 1 0 0 1 1 1 0 Presenilin Hydrolase_6 PF13344.6 PFH31905.1 - 2.6e-34 117.3 0.0 5.6e-34 116.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PFH31905.1 - 1.2e-15 57.3 0.3 7.7e-15 54.7 0.0 2.5 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 PFH31905.1 - 8.8e-05 22.9 0.3 0.00021 21.7 0.3 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 PFH31905.1 - 0.018 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase RCC1 PF00415.18 PFH31906.1 - 9.6e-22 77.4 17.5 1.4e-06 28.8 1.8 8.5 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH31906.1 - 1.4e-08 34.3 32.3 0.00011 21.8 2.8 6.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat zf-His_Me_endon PF05551.11 PFH31909.1 - 0.043 14.0 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease Histone PF00125.24 PFH31911.1 - 2e-20 73.5 0.4 2.4e-20 73.2 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PFH31911.1 - 5.9e-05 23.3 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 PFH31911.1 - 0.00082 19.8 0.0 0.0012 19.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A PAN_1 PF00024.26 PFH31912.1 - 8.1e-26 89.8 32.4 6.4e-08 32.5 4.1 4.5 2 2 2 4 4 4 4 PAN domain PAN_4 PF14295.6 PFH31912.1 - 1.5e-16 60.0 32.0 2.7e-05 24.0 1.9 4.8 4 1 0 4 4 4 4 PAN domain PAN_2 PF08276.11 PFH31912.1 - 0.0091 16.1 34.3 0.029 14.5 1.8 5.0 4 1 2 6 6 6 4 PAN-like domain SinI PF08671.10 PFH31913.1 - 0.046 13.5 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Anti-repressor SinI SOG2 PF10428.9 PFH31913.1 - 2 7.5 18.1 3.2 6.8 18.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein EamA PF00892.20 PFH31914.1 - 2.7e-09 37.3 17.9 9.7e-05 22.6 0.3 3.3 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 PFH31914.1 - 2e-07 30.7 6.8 2.5e-07 30.4 6.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 PFH31914.1 - 1.6e-05 24.2 2.3 3.2e-05 23.3 2.3 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 PFH31914.1 - 0.00033 20.0 10.9 0.00042 19.6 10.9 1.3 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 PFH31914.1 - 0.00068 19.0 11.5 0.0013 18.1 11.5 1.5 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 PFH31914.1 - 0.0058 15.6 1.4 0.01 14.8 1.4 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Herpes_UL79 PF03049.14 PFH31914.1 - 0.025 14.3 0.2 0.041 13.5 0.2 1.3 1 0 0 1 1 1 0 UL79 family DUF1129 PF06570.11 PFH31914.1 - 0.039 13.4 1.2 0.09 12.3 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Thioredoxin PF00085.20 PFH31916.1 - 9.1e-20 70.6 0.1 2.8e-11 43.3 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 PFH31916.1 - 7.3e-08 32.5 2.4 0.0034 17.3 0.3 3.3 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 PFH31916.1 - 0.0001 22.7 1.1 0.086 13.3 0.0 3.5 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PFH31916.1 - 0.00012 22.3 0.6 0.77 10.1 0.1 3.6 3 1 0 3 3 3 2 Thioredoxin-like HyaE PF07449.11 PFH31916.1 - 0.0018 18.2 0.1 0.37 10.8 0.0 3.3 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 PFH31916.1 - 0.039 14.0 0.3 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin domain OST3_OST6 PF04756.13 PFH31916.1 - 0.067 12.5 2.4 11 5.2 0.0 3.2 2 1 1 3 3 3 0 OST3 / OST6 family, transporter family TelA PF05816.11 PFH31916.1 - 0.095 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Glycos_transf_1 PF00534.20 PFH31917.1 - 6.9e-37 126.6 0.0 1.1e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PFH31917.1 - 1.3e-30 106.6 1.7 1.3e-29 103.3 0.4 3.2 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 PFH31917.1 - 2.1e-27 96.2 0.0 7.7e-27 94.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 PFH31917.1 - 3.7e-21 76.2 0.5 3.7e-21 76.2 0.5 4.3 5 0 0 5 5 5 1 Glycosyl transferase 4-like domain Alpha-amylase_C PF02806.18 PFH31917.1 - 3.3e-14 53.1 0.0 1.6e-13 50.9 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Glyco_transf_5 PF08323.11 PFH31917.1 - 4.8e-13 49.4 0.9 1.1e-10 41.7 0.9 2.7 1 1 0 1 1 1 1 Starch synthase catalytic domain CBM_48 PF02922.18 PFH31917.1 - 2.6e-09 37.3 0.1 3.4e-05 24.1 0.0 2.6 2 0 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 PFH31917.1 - 5.1e-06 26.3 0.0 1.2e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_trans_1_2 PF13524.6 PFH31917.1 - 0.00053 20.3 0.0 0.0066 16.8 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycogen_syn PF05693.13 PFH31917.1 - 0.058 11.9 0.0 0.33 9.4 0.0 1.9 2 0 0 2 2 2 0 Glycogen synthase Glyco_trans_4_2 PF13477.6 PFH31917.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like GCP_C_terminal PF04130.13 PFH31918.1 - 3.4e-31 108.8 1.1 6.5e-25 88.2 0.0 2.3 2 0 0 2 2 2 2 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PFH31918.1 - 6.5e-29 101.5 0.0 4.3e-24 85.7 0.0 2.6 2 0 0 2 2 2 2 Gamma tubulin complex component N-terminal Kinase-like PF14531.6 PFH31919.1 - 3.9e-29 101.9 0.0 5.2e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH31919.1 - 2.4e-15 56.6 0.0 1.7e-14 53.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH31919.1 - 1e-09 38.1 0.0 1.5e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase HABP4_PAI-RBP1 PF04774.15 PFH31922.1 - 4.5e-07 30.7 15.5 4.5e-07 30.7 15.5 2.8 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Glyco_transf_22 PF03901.17 PFH31923.1 - 1.7e-78 264.7 8.2 2.5e-78 264.2 8.2 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.25 PFH31924.1 - 2.6e-09 36.8 0.0 1.5e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain TetR_C_11 PF16859.5 PFH31926.1 - 0.0017 18.7 0.6 0.0042 17.4 0.6 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 PFH31927.1 - 1.3e-11 44.3 0.0 7e-11 42.0 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase PF00069.25 PFH31928.1 - 4.9e-11 42.5 0.0 2.2e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain AAA PF00004.29 PFH31930.1 - 2.4e-92 306.2 0.0 2.7e-45 154.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PFH31930.1 - 3.2e-24 84.4 4.0 3.8e-11 42.6 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 PFH31930.1 - 2.9e-13 49.9 0.0 2.2e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PFH31930.1 - 2.4e-12 47.6 2.1 0.00013 22.4 0.3 4.4 3 2 0 3 3 2 2 AAA ATPase domain AAA_33 PF13671.6 PFH31930.1 - 6.5e-12 45.8 0.0 4.8e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 PFH31930.1 - 3e-10 40.3 0.0 2.2e-05 24.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 PFH31930.1 - 8.1e-10 39.1 0.0 0.00058 20.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 PFH31930.1 - 9.6e-09 35.4 0.0 0.0011 19.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 PFH31930.1 - 3.1e-08 33.7 0.0 5.3e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.6 PFH31930.1 - 6.9e-08 32.9 3.1 0.076 13.3 0.0 4.5 3 2 1 4 4 3 2 AAA domain CDC48_N PF02359.18 PFH31930.1 - 8.1e-08 32.3 0.0 1.9e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain TIP49 PF06068.13 PFH31930.1 - 2e-07 30.5 0.0 0.0031 16.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 PFH31930.1 - 2.6e-07 31.0 0.0 0.021 15.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 PFH31930.1 - 1.2e-06 29.1 0.3 0.051 14.1 0.2 2.8 2 1 0 2 2 2 2 ABC transporter Viral_helicase1 PF01443.18 PFH31930.1 - 1.4e-06 28.2 0.0 0.015 15.0 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 PFH31930.1 - 1.9e-06 27.9 0.0 0.034 14.1 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 PFH31930.1 - 2.5e-06 27.5 1.5 0.097 12.6 0.1 3.3 3 0 0 3 3 3 2 NACHT domain AAA_28 PF13521.6 PFH31930.1 - 2.7e-06 27.7 0.0 0.092 13.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 PFH31930.1 - 3.7e-06 26.8 0.1 0.099 12.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein DUF815 PF05673.13 PFH31930.1 - 1.1e-05 24.7 0.0 0.086 12.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 PFH31930.1 - 1.3e-05 24.7 0.3 0.031 13.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 PFH31930.1 - 1.3e-05 24.9 0.3 0.02 14.6 0.2 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 PFH31930.1 - 1.4e-05 24.5 0.1 0.029 13.7 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin AAA_18 PF13238.6 PFH31930.1 - 2.2e-05 25.0 0.0 0.093 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 PFH31930.1 - 3.2e-05 23.5 0.1 0.15 11.5 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 PFH31930.1 - 7.4e-05 22.0 0.1 0.47 9.6 0.1 2.7 3 0 0 3 3 3 2 NB-ARC domain ATPase PF06745.13 PFH31930.1 - 0.00018 20.9 0.2 0.67 9.3 0.0 3.1 3 0 0 3 3 3 2 KaiC Cytidylate_kin2 PF13189.6 PFH31930.1 - 0.00021 21.5 0.0 0.1 12.7 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family ATPase_2 PF01637.18 PFH31930.1 - 0.00069 19.6 0.0 0.43 10.5 0.0 2.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 PFH31930.1 - 0.00096 19.3 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.9 PFH31930.1 - 0.0011 18.3 0.0 0.27 10.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 PFH31930.1 - 0.0012 18.8 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain Parvo_NS1 PF01057.17 PFH31930.1 - 0.0019 17.4 0.1 0.4 9.7 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 PhoH PF02562.16 PFH31930.1 - 0.0019 17.7 0.1 2.5 7.5 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 PFH31930.1 - 0.0021 17.9 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 PFH31930.1 - 0.005 16.6 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Molydop_binding PF01568.21 PFH31930.1 - 0.0056 16.7 0.1 0.41 10.7 0.0 2.9 2 1 1 3 3 3 1 Molydopterin dinucleotide binding domain AAA_17 PF13207.6 PFH31930.1 - 0.0058 17.1 0.0 1.6 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PFH31930.1 - 0.0066 16.2 0.0 3.4 7.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain Vps4_C PF09336.10 PFH31930.1 - 0.0067 16.4 0.0 0.59 10.2 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 PFH31930.1 - 0.0075 15.9 2.5 3.1 7.3 0.0 3.5 2 1 0 3 3 3 1 AAA domain SKI PF01202.22 PFH31930.1 - 0.012 15.8 0.1 6 7.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.15 PFH31930.1 - 0.022 14.7 0.1 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 NTPase CPT PF07931.12 PFH31930.1 - 0.07 13.0 0.2 1.6 8.5 0.0 2.8 3 1 0 4 4 2 0 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 PFH31930.1 - 0.082 12.3 0.0 16 4.8 0.0 3.2 2 1 1 3 3 3 0 Bacterial TniB protein AAA_29 PF13555.6 PFH31930.1 - 0.13 12.0 0.1 15 5.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Hydin_ADK PF17213.3 PFH31930.1 - 2.6 8.3 5.0 29 4.9 0.0 3.8 4 0 0 4 4 3 0 Hydin Adenylate kinase-like domain RRM_1 PF00076.22 PFH31931.1 - 2.7e-40 136.1 0.6 9.2e-19 67.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH31931.1 - 2e-08 34.2 0.1 4.9e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 PFH31931.1 - 2.4e-08 33.7 0.0 0.0084 15.9 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 PFH31931.1 - 8.5e-06 25.4 0.0 0.12 12.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PFH31931.1 - 0.00021 21.3 0.2 0.8 9.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 PFH31931.1 - 0.0022 18.0 0.0 0.21 11.7 0.0 2.7 2 0 0 2 2 2 1 RNA binding motif DUF1866 PF08952.11 PFH31931.1 - 0.033 14.0 0.0 4.8 7.0 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1866) Limkain-b1 PF11608.8 PFH31931.1 - 0.037 14.1 0.1 1.6 8.8 0.0 3.2 3 0 0 3 3 3 0 Limkain b1 RRM_8 PF11835.8 PFH31931.1 - 0.042 14.0 0.0 4.7 7.5 0.0 3.0 3 0 0 3 3 3 0 RRM-like domain Dynamin_M PF01031.20 PFH31932.1 - 4e-80 269.1 0.3 1e-79 267.8 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 PFH31932.1 - 2.5e-49 167.5 0.0 5.9e-49 166.4 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 PFH31932.1 - 3.2e-24 84.9 1.2 1.6e-23 82.7 0.3 2.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 PFH31932.1 - 6.6e-05 23.0 0.0 0.00019 21.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 PFH31932.1 - 0.028 14.3 0.0 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Glutaredoxin2_C PF04399.13 PFH31932.1 - 0.1 12.5 0.6 0.88 9.4 0.1 2.4 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Apolipoprotein PF01442.18 PFH31932.1 - 0.11 12.4 2.1 2.4 8.0 0.5 3.4 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain AAA_18 PF13238.6 PFH31932.1 - 0.11 13.0 0.1 1.3 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Cas_Cas7 PF05107.12 PFH31932.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein Cas7 AAA_15 PF13175.6 PFH31932.1 - 0.12 12.1 0.0 0.39 10.4 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF4539 PF15072.6 PFH31933.1 - 4.9e-16 58.5 0.0 8.2e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) V_ATPase_I PF01496.19 PFH31934.1 - 0.022 12.7 1.6 0.031 12.2 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 PFH31934.1 - 2.8 6.4 11.9 8.1 4.9 11.9 1.8 1 1 0 1 1 1 0 Macoilin family Fez1 PF06818.15 PFH31934.1 - 3 8.2 15.7 6.4 7.2 15.7 1.5 1 0 0 1 1 1 0 Fez1 YTV PF07639.11 PFH31935.1 - 0.15 12.1 1.2 0.24 11.5 1.2 1.3 1 0 0 1 1 1 0 YTV OST3_OST6 PF04756.13 PFH31936.1 - 0.012 14.9 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family FabA PF07977.13 PFH31938.1 - 1e-29 102.9 0.0 1.3e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 PFH31938.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 MaoC like domain MaoC_dehydrat_N PF13452.6 PFH31938.1 - 0.084 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase CTD_bind PF04818.13 PFH31939.1 - 3.6e-13 50.1 0.1 7.3e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-CCHC PF00098.23 PFH31939.1 - 7.7e-07 28.9 1.0 7.7e-07 28.9 1.0 2.6 3 0 0 3 3 3 1 Zinc knuckle Surp PF01805.20 PFH31939.1 - 0.00057 19.8 0.3 0.0018 18.2 0.0 2.0 2 0 0 2 2 2 1 Surp module DUF3563 PF12086.8 PFH31939.1 - 0.018 14.7 0.3 0.061 13.1 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) SR-25 PF10500.9 PFH31939.1 - 0.11 12.1 12.6 0.19 11.3 12.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-CCHC_5 PF14787.6 PFH31939.1 - 0.13 12.0 0.9 0.33 10.7 0.9 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 PFH31939.1 - 0.24 11.2 0.4 0.42 10.4 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Peptidase_C1 PF00112.23 PFH31942.1 - 4.4e-75 252.5 0.3 6e-75 252.1 0.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PFH31942.1 - 4.7e-16 59.0 0.8 7.3e-16 58.4 0.8 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PFH31942.1 - 0.00049 19.0 3.0 0.032 13.0 0.3 2.3 2 0 0 2 2 2 2 Peptidase C1-like family DUF2277 PF10041.9 PFH31942.1 - 0.088 13.1 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) RsdA_SigD_bd PF16751.5 PFH31942.1 - 0.25 11.6 2.1 0.41 10.9 0.5 2.1 2 0 0 2 2 2 0 Anti-sigma-D factor RsdA to sigma factor binding region CS PF04969.16 PFH31943.1 - 2.1e-08 35.0 0.3 3.1e-08 34.5 0.3 1.2 1 0 0 1 1 1 1 CS domain Forkhead_N PF08430.12 PFH31943.1 - 5.2 7.7 8.9 8.5 7.0 8.9 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region RRM_1 PF00076.22 PFH31944.1 - 5.3e-55 183.1 1.3 3.1e-17 62.1 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 PFH31944.1 - 3.5e-09 36.6 6.6 7.5e-09 35.5 6.6 1.6 1 0 0 1 1 1 1 WW domain RRM_7 PF16367.5 PFH31944.1 - 1.8e-08 34.4 0.6 0.027 14.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 PFH31944.1 - 1.9e-08 33.9 0.1 0.12 11.9 0.1 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 PFH31944.1 - 2.6e-06 27.6 0.0 0.091 13.0 0.0 3.1 3 0 0 3 3 3 2 BRCA1-associated protein 2 RNA_bind PF08675.11 PFH31944.1 - 3.1e-05 23.9 0.1 0.013 15.5 0.1 3.3 3 1 0 3 3 3 1 RNA binding domain PHM7_cyt PF14703.6 PFH31944.1 - 0.00052 20.3 1.2 12 6.1 0.0 3.8 3 2 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 PFH31944.1 - 0.008 16.0 0.0 5.1 7.0 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 PFH31944.1 - 0.016 15.2 1.0 39 4.3 0.1 3.6 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Myb_DNA-binding PF00249.31 PFH31945.1 - 0.0012 19.0 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SNF2_N PF00176.23 PFH31946.1 - 1.2e-64 218.3 0.0 2.4e-64 217.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 PFH31946.1 - 6.1e-35 119.7 1.6 1.8e-34 118.1 0.3 2.6 2 1 1 3 3 3 1 SLIDE Helicase_C PF00271.31 PFH31946.1 - 1.2e-19 70.7 0.0 2.5e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH31946.1 - 6.6e-09 36.0 0.0 4.6e-08 33.3 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HAND PF09110.11 PFH31946.1 - 0.00097 19.9 1.8 0.00097 19.9 1.8 3.6 3 1 1 4 4 4 1 HAND DEAD PF00270.29 PFH31946.1 - 0.02 14.7 4.2 0.061 13.1 0.1 3.4 4 0 0 4 4 4 0 DEAD/DEAH box helicase OKR_DC_1_N PF03709.15 PFH31946.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain AAA_11 PF13086.6 PFH31946.1 - 1.3 8.7 17.0 0.13 12.0 0.2 3.1 3 1 0 3 3 3 0 AAA domain Rad51 PF08423.11 PFH31947.1 - 3.6e-18 65.8 0.0 9.8e-07 28.3 0.0 3.8 3 1 0 3 3 3 3 Rad51 ATPase PF06745.13 PFH31947.1 - 2.5e-06 27.0 0.0 8.7e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 PFH31947.1 - 1.4e-05 24.8 0.1 0.019 14.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain RecA PF00154.21 PFH31947.1 - 4.5e-05 23.0 0.0 0.0016 18.0 0.0 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein Kelch_3 PF13415.6 PFH31948.1 - 2e-19 69.4 8.1 5.2e-05 23.4 0.0 4.5 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_4 PF13418.6 PFH31948.1 - 4.5e-10 39.4 11.5 0.025 14.6 0.0 4.7 5 0 0 5 5 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PFH31948.1 - 8.5e-10 38.6 8.1 0.018 15.3 0.0 5.1 5 0 0 5 5 4 3 Kelch motif Kelch_5 PF13854.6 PFH31948.1 - 1.2e-09 37.9 1.7 0.0029 17.5 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 PFH31948.1 - 4e-05 23.4 7.6 3.7 7.7 0.1 5.6 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 PFH31948.1 - 0.0001 21.8 22.0 0.43 10.2 0.3 6.4 6 1 0 6 6 6 3 Kelch motif ApoLp-III PF07464.11 PFH31948.1 - 0.0025 17.9 2.2 0.0025 17.9 2.2 1.8 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Golgin_A5 PF09787.9 PFH31948.1 - 0.03 13.8 2.7 0.042 13.3 2.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 PFH31948.1 - 0.63 10.1 4.5 0.29 11.2 0.7 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 PFH31948.1 - 0.78 10.0 4.1 0.55 10.5 1.6 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 PFH31948.1 - 0.86 8.4 6.5 1.2 8.0 6.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF745 PF05335.13 PFH31948.1 - 2.4 7.8 6.5 5.2 6.7 6.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Uso1_p115_C PF04871.13 PFH31948.1 - 4.5 7.7 8.4 0.55 10.6 0.9 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region NDUF_B5 PF09781.9 PFH31949.1 - 0.15 11.6 1.9 0.64 9.6 1.9 2.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit SPC12 PF06645.13 PFH31950.1 - 3.7e-20 71.8 0.1 5.2e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Sld7_C PF18596.1 PFH31952.1 - 0.37 11.0 1.1 0.71 10.0 0.2 1.9 2 0 0 2 2 2 0 Sld7 C-terminal domain RRM_1 PF00076.22 PFH31954.1 - 1.3e-32 111.4 0.0 4.7e-15 55.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 PFH31954.1 - 2.4e-09 37.1 4.8 4.5e-09 36.2 4.8 1.5 1 0 0 1 1 1 1 WW domain RRM_7 PF16367.5 PFH31954.1 - 2.2e-07 30.9 0.0 0.0036 17.4 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif RNA_bind PF08675.11 PFH31954.1 - 0.00086 19.3 0.0 0.0078 16.2 0.0 2.2 2 0 0 2 2 2 1 RNA binding domain Nup35_RRM_2 PF14605.6 PFH31954.1 - 0.001 19.0 0.0 0.25 11.4 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 PFH31954.1 - 0.0065 16.4 0.0 0.74 9.8 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 PFH31954.1 - 0.019 15.2 1.1 2.9 8.1 0.1 3.6 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter DUF1138 PF06592.13 PFH31954.1 - 0.1 12.7 1.2 1.2 9.3 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1138) Glyco_hyd_101C PF17451.2 PFH31954.1 - 0.11 12.7 0.6 0.28 11.5 0.6 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain DUF747 PF05346.11 PFH31955.1 - 1.7e-128 428.6 18.5 2.2e-128 428.3 18.5 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family EF-hand_1 PF00036.32 PFH31957.1 - 2.5e-10 39.2 7.0 0.00027 20.3 0.2 4.6 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 PFH31957.1 - 3.9e-10 40.0 0.1 0.29 11.6 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 PFH31957.1 - 5.3e-10 38.4 1.3 0.25 11.4 0.2 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 PFH31957.1 - 1.9e-06 27.6 5.7 0.2 11.5 0.2 4.5 5 0 0 5 5 5 3 EF-hand domain pair Pkinase PF00069.25 PFH31957.1 - 2.2e-05 24.0 0.0 3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EF-hand_5 PF13202.6 PFH31957.1 - 0.0004 19.7 12.8 0.005 16.3 0.4 4.1 4 0 0 4 4 4 2 EF hand CysG_dimeriser PF10414.9 PFH31958.1 - 0.011 15.4 2.1 0.072 12.8 2.1 2.5 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Ephrin_rec_like PF07699.13 PFH31959.1 - 7.4e-25 86.5 117.1 7.2e-09 35.3 4.4 11.8 13 0 0 13 13 13 9 Putative ephrin-receptor like Cnn_1N PF07989.11 PFH31959.1 - 0.11 12.7 1.8 0.67 10.2 1.5 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Prefoldin_2 PF01920.20 PFH31959.1 - 0.66 10.0 3.3 1.5 8.8 3.3 1.5 1 0 0 1 1 1 0 Prefoldin subunit He_PIG PF05345.12 PFH31959.1 - 1.2 9.4 13.5 0.0052 16.9 2.2 3.2 3 0 0 3 3 3 0 Putative Ig domain TFIIB PF00382.19 PFH31960.1 - 2.4e-13 49.9 5.2 4.2e-07 29.9 0.1 2.8 3 0 0 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 PFH31960.1 - 5.8e-09 35.3 0.8 1.2e-08 34.3 0.8 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 PFH31960.1 - 0.0079 15.6 2.0 0.98 8.9 0.3 2.5 2 0 0 2 2 2 2 zinc-ribbon domain Cyclin_C PF02984.19 PFH31960.1 - 0.013 15.6 0.1 0.095 12.8 0.1 2.1 1 1 1 2 2 2 0 Cyclin, C-terminal domain DZR PF12773.7 PFH31960.1 - 0.21 11.6 2.0 0.22 11.6 0.4 1.9 2 0 0 2 2 2 0 Double zinc ribbon mTERF PF02536.14 PFH31961.1 - 6.8e-14 51.5 0.1 8.2e-11 41.4 0.3 2.2 2 0 0 2 2 2 2 mTERF HECT PF00632.25 PFH31962.1 - 4.3e-62 210.3 0.0 1.8e-58 198.4 0.0 2.1 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) Kinase-like PF14531.6 PFH31963.1 - 1.9e-19 70.1 0.0 3e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RRM_1 PF00076.22 PFH31964.1 - 1.9e-22 78.9 0.0 1.2e-13 50.6 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH31964.1 - 9.1e-07 28.9 0.0 0.003 17.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 PFH31964.1 - 0.036 13.9 0.0 4.3 7.3 0.0 3.3 3 0 0 3 3 3 0 Occluded RNA-recognition motif MatE PF01554.18 PFH31965.1 - 0.006 16.2 23.3 0.033 13.9 4.8 4.4 4 0 0 4 4 4 3 MatE GTA_holin_3TM PF11351.8 PFH31965.1 - 0.3 11.6 1.7 23 5.6 0.8 2.6 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release RRM_1 PF00076.22 PFH31966.1 - 3.2e-39 132.6 0.2 9.9e-19 66.9 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PFH31966.1 - 7.6e-07 29.0 0.0 0.0067 16.4 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 PFH31966.1 - 0.0032 17.3 0.0 0.62 10.0 0.0 2.7 2 0 0 2 2 2 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 PFH31966.1 - 0.0097 16.1 6.0 0.71 10.1 0.2 3.4 3 2 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 PFH31966.1 - 0.075 13.2 0.0 3.2 7.9 0.0 3.1 2 1 0 2 2 2 0 RNA recognition motif RRM_3 PF08777.11 PFH31966.1 - 0.079 13.0 0.1 2.2 8.4 0.0 2.8 2 0 0 2 2 2 0 RNA binding motif ETRAMP PF09716.10 PFH31967.1 - 0.019 15.0 0.0 0.61 10.2 0.0 3.0 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Tfb4 PF03850.14 PFH31967.1 - 0.53 9.7 2.4 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Transcription factor Tfb4 MAR_sialic_bdg PF10564.9 PFH31969.1 - 6.5e-65 215.2 20.9 1.5e-22 79.4 1.8 4.7 5 0 0 5 5 5 4 Sialic-acid binding micronemal adhesive repeat TgMIC1 PF11476.8 PFH31969.1 - 2.2e-28 98.7 1.7 3.7e-28 98.0 1.7 1.3 1 0 0 1 1 1 1 Toxoplasma gondii micronemal protein 1 TgMIC1 HORMA PF02301.18 PFH31971.1 - 1.5e-35 122.7 0.0 2.2e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 HORMA domain Ribosomal_S30 PF04758.14 PFH31971.1 - 2.5e-24 85.2 11.6 4.8e-24 84.3 11.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S30 Rrf2 PF02082.20 PFH31971.1 - 0.025 14.9 0.1 0.068 13.5 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulator Ribosomal_S25 PF03297.15 PFH31971.1 - 0.069 13.4 0.0 0.069 13.4 0.0 2.4 2 1 0 2 2 2 0 S25 ribosomal protein HTH_36 PF13730.6 PFH31971.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 PFH31971.1 - 0.16 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Mnd1 PF03962.15 PFH31971.1 - 0.24 11.7 0.4 0.59 10.5 0.1 1.8 2 0 0 2 2 2 0 Mnd1 HTH domain HSBP1 PF06825.12 PFH31972.1 - 0.043 13.7 1.4 6.1 6.8 0.1 3.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Arg_decarbox_C PF17944.1 PFH31972.1 - 0.063 13.8 1.3 16 6.1 0.1 4.0 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension Baculo_PEP_C PF04513.12 PFH31972.1 - 3 7.9 8.7 4.7 7.3 0.2 4.1 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF1_Zn_bind PF09416.10 PFH31973.1 - 4.5e-61 205.3 4.4 7.1e-61 204.6 4.4 1.3 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 PFH31973.1 - 3e-57 193.5 0.0 6.2e-57 192.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PFH31973.1 - 4.1e-48 164.4 0.5 4.7e-46 157.7 0.5 2.3 1 1 0 1 1 1 1 AAA domain DUF5599 PF18141.1 PFH31973.1 - 3.8e-14 52.7 0.0 3e-08 33.8 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF5599) AAA_30 PF13604.6 PFH31973.1 - 8e-11 42.0 0.0 7.1e-10 38.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PFH31973.1 - 2.5e-09 37.6 1.5 5.8e-09 36.4 0.0 2.3 3 0 0 3 3 2 1 AAA domain DEAD PF00270.29 PFH31973.1 - 3.6e-05 23.6 0.4 0.00039 20.2 0.0 2.5 2 1 0 3 3 3 1 DEAD/DEAH box helicase DUF2075 PF09848.9 PFH31973.1 - 0.0029 16.9 0.3 0.041 13.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 PFH31973.1 - 0.0056 16.3 0.2 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PFH31973.1 - 0.012 15.9 0.3 0.1 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 PFH31973.1 - 0.012 15.3 0.1 6.6 6.4 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 PFH31973.1 - 0.028 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 PFH31973.1 - 0.035 14.5 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 PFH31973.1 - 0.045 13.3 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PhoH PF02562.16 PFH31973.1 - 0.22 10.9 0.0 0.49 9.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Thioredoxin PF00085.20 PFH31974.1 - 5.2e-08 32.8 0.1 1.1e-07 31.7 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Importin_rep_6 PF18829.1 PFH31974.1 - 0.02 15.0 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Importin repeat 6 AKAP95 PF04988.12 PFH31974.1 - 0.056 13.7 1.1 0.066 13.4 0.2 1.5 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) ASH PF15780.5 PFH31975.1 - 0.0014 18.8 0.1 0.0027 17.9 0.1 1.4 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 PFH31975.1 - 0.003 17.7 0.0 0.0082 16.3 0.0 1.7 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Motile_Sperm PF00635.26 PFH31975.1 - 0.019 14.8 0.2 0.048 13.5 0.2 1.7 1 0 0 1 1 1 0 MSP (Major sperm protein) domain fn3_5 PF06280.12 PFH31975.1 - 0.13 12.9 0.4 0.13 12.9 0.4 2.2 2 1 0 2 2 2 0 Fn3-like domain Arf PF00025.21 PFH31976.1 - 9.1e-30 103.4 0.0 1.1e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PFH31976.1 - 0.001 18.7 0.0 0.0013 18.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 PFH31976.1 - 0.0018 17.8 0.0 0.023 14.1 0.0 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 PFH31976.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase CLLAC PF15675.5 PFH31977.1 - 0.29 10.7 2.4 0.57 9.8 2.4 1.4 1 0 0 1 1 1 0 CLLAC-motif containing domain Sec23_trunk PF04811.15 PFH31978.1 - 5.6e-58 196.4 0.0 7.8e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 PFH31978.1 - 9.7e-31 106.4 0.1 1.9e-30 105.5 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 PFH31978.1 - 3.7e-24 84.5 0.5 8.8e-24 83.3 0.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 PFH31978.1 - 7.2e-13 48.3 4.7 1.5e-12 47.3 4.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 PFH31978.1 - 1.9e-12 46.9 0.1 5.4e-12 45.4 0.1 1.8 1 1 0 1 1 1 1 Gelsolin repeat DEAD PF00270.29 PFH31979.1 - 3.1e-27 95.4 0.0 5.2e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH31979.1 - 2e-20 73.2 0.0 3.7e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RasGAP PF00616.19 PFH31980.1 - 0.091 12.5 0.1 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase OTCace_N PF02729.21 PFH31981.1 - 1.3e-34 119.4 0.0 2.1e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 PFH31981.1 - 9.4e-30 103.8 0.0 1.5e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Big_9 PF17963.1 PFH31982.1 - 0.089 13.5 0.4 0.089 13.5 0.4 1.7 2 0 0 2 2 2 0 Bacterial Ig domain DUF1635 PF07795.11 PFH31983.1 - 0.00033 20.6 3.1 0.00033 20.6 3.1 6.0 6 1 1 7 7 7 2 Protein of unknown function (DUF1635) GILT PF03227.16 PFH31984.1 - 1.1e-24 86.7 0.7 4.2e-24 84.8 0.1 2.0 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) zf-MYND PF01753.18 PFH31985.1 - 4.2e-05 23.6 0.4 4.2e-05 23.6 0.4 2.1 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 PFH31985.1 - 0.045 13.9 0.2 0.12 12.4 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Herpes_UL16 PF03044.14 PFH31986.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family Bowman-Birk_leg PF00228.20 PFH31988.1 - 0.064 13.7 2.2 15 6.1 0.0 2.5 2 0 0 2 2 2 0 Bowman-Birk serine protease inhibitor family RRM_1 PF00076.22 PFH31989.1 - 3.8e-15 55.5 0.0 5.5e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PFH31989.1 - 0.0038 17.2 0.0 0.0058 16.7 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif DUF4651 PF15513.6 PFH31989.1 - 0.017 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) ATP-synt_C PF00137.21 PFH31991.1 - 4.8e-31 106.9 25.8 2.5e-16 59.7 11.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TadF PF16964.5 PFH31991.1 - 0.0087 15.8 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 1 Putative tight adherence pilin protein F Oxidored_q2 PF00420.24 PFH31991.1 - 0.056 13.1 4.5 0.071 12.8 0.1 2.7 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Rer1 PF03248.13 PFH31992.1 - 1.1e-54 184.8 6.7 1.4e-54 184.4 6.7 1.1 1 0 0 1 1 1 1 Rer1 family DUF5592 PF17332.2 PFH31992.1 - 2.1 8.9 7.2 0.095 13.3 1.5 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5592) DUF1980 PF09323.10 PFH31992.1 - 3.6 7.5 6.3 0.2 11.5 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF2208 PF09973.9 PFH31992.1 - 8.1 6.0 9.2 0.43 10.2 3.9 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Chorein_N PF12624.7 PFH31994.1 - 3.7e-30 104.4 0.0 7.6e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 PFH31994.1 - 1.2e-12 48.2 0.0 5.8e-11 42.6 0.0 3.0 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 PFH31994.1 - 2.5e-05 23.8 0.0 0.00015 21.3 0.0 2.0 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 PFH31994.1 - 9.6e-05 22.7 0.0 0.00063 20.0 0.0 2.5 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 PFH31994.1 - 0.1 12.3 0.4 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal Dynein_light PF01221.18 PFH31995.1 - 6.5e-22 77.6 0.0 8.1e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Not1 PF04054.15 PFH31998.1 - 5.6e-127 423.7 0.4 5.3e-126 420.5 0.4 2.1 1 1 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 PFH31998.1 - 3.8e-74 248.8 0.2 6.7e-74 248.1 0.2 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 PFH31998.1 - 2e-56 190.0 2.6 3.4e-56 189.2 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 PFH31998.1 - 1.3e-42 145.1 0.0 2.6e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain Mon1 PF03164.14 PFH32000.1 - 3e-83 280.2 0.0 2e-82 277.4 0.0 1.9 1 1 0 1 1 1 1 Trafficking protein Mon1 SNF2_N PF00176.23 PFH32001.1 - 6.6e-40 136.9 0.0 1e-39 136.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PFH32001.1 - 8.4e-08 32.5 0.0 1.6e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH32001.1 - 4.6e-05 23.5 0.0 9.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 PFH32001.1 - 0.1 11.7 0.0 0.43 9.7 0.0 1.9 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 TBP PF00352.21 PFH32002.1 - 2.2e-33 114.0 0.0 1.6e-16 60.0 0.1 2.8 2 1 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) FliD_C PF07195.12 PFH32003.1 - 0.087 12.2 1.0 0.14 11.6 1.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus YscO-like PF16789.5 PFH32003.1 - 0.21 11.6 7.5 0.4 10.7 7.5 1.4 1 0 0 1 1 1 0 YscO-like protein AAA_15 PF13175.6 PFH32003.1 - 0.98 9.1 3.1 1.4 8.5 3.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF16 PF01519.16 PFH32003.1 - 2.1 8.9 8.3 0.8 10.2 5.1 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 PFH32003.1 - 2.8 8.4 4.0 6.7 7.2 4.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.25 PFH32004.1 - 2e-75 253.6 0.0 2.5e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32004.1 - 4.7e-42 144.1 0.0 6.3e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH32004.1 - 5.9e-05 22.5 0.0 9.6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PFH32004.1 - 0.00049 19.1 0.9 0.00072 18.6 0.9 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PFH32004.1 - 0.0034 16.8 0.2 0.0058 16.0 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PFH32004.1 - 0.0059 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 PFH32004.1 - 0.012 15.6 1.3 0.06 13.3 0.1 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ldh_1_N PF00056.23 PFH32005.1 - 3.8e-33 114.5 0.1 8.1e-33 113.5 0.1 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 PFH32005.1 - 5.7e-31 107.7 0.0 9.5e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 PFH32005.1 - 0.011 15.3 0.1 0.033 13.8 0.1 1.7 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase zf-RING_2 PF13639.6 PFH32007.1 - 6.5e-11 42.4 10.0 1.4e-10 41.3 10.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PFH32007.1 - 2.1e-07 30.6 1.3 4.3e-07 29.6 1.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PFH32007.1 - 5e-07 29.4 8.9 1.1e-06 28.4 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PFH32007.1 - 1.1e-06 28.8 9.4 2.4e-06 27.7 9.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PFH32007.1 - 3.6e-05 23.5 5.3 6.7e-05 22.7 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PFH32007.1 - 0.00082 19.0 7.5 0.002 17.7 7.5 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 PFH32007.1 - 0.00098 18.9 8.1 0.0022 17.8 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH32007.1 - 0.001 19.0 6.6 0.0018 18.2 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PFH32007.1 - 0.0011 18.9 5.8 0.0025 17.8 5.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 PFH32007.1 - 0.0077 16.3 3.7 0.018 15.1 3.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PFH32007.1 - 0.013 15.4 7.5 0.027 14.3 7.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PFH32007.1 - 0.24 11.2 5.0 0.54 10.1 5.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 PFH32007.1 - 0.56 10.2 4.6 1.3 9.1 4.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_10 PF16685.5 PFH32007.1 - 1.9 8.7 5.0 3.6 7.8 5.0 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Myosin_head PF00063.21 PFH32008.1 - 5e-37 127.5 0.0 7.3e-25 87.3 0.0 3.1 3 0 0 3 3 3 3 Myosin head (motor domain) RCC1 PF00415.18 PFH32008.1 - 7.7e-28 96.9 8.6 9.4e-09 35.8 0.0 7.4 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH32008.1 - 1.7e-06 27.6 25.3 0.0021 17.8 2.5 5.9 5 1 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 PFH32008.1 - 0.0054 16.4 40.1 0.17 11.8 0.7 6.9 7 0 0 7 7 7 5 IQ calmodulin-binding motif Skp1_POZ PF03931.15 PFH32009.1 - 2.1e-05 24.6 0.0 9.7e-05 22.5 0.0 2.0 2 1 0 2 2 2 1 Skp1 family, tetramerisation domain ISP3_C PF18045.1 PFH32010.1 - 5.1e-28 97.1 0.4 5.9e-28 96.9 0.4 1.0 1 0 0 1 1 1 1 ISP3 C-terminal ISP1_C PF18161.1 PFH32010.1 - 6e-28 97.0 0.4 7e-28 96.7 0.4 1.1 1 0 0 1 1 1 1 ISP1 C-terminal zf-HC5HC2H_2 PF13832.6 PFH32011.1 - 4.5e-16 59.0 2.5 4.5e-16 59.0 2.5 3.1 1 1 3 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PFH32011.1 - 2.4e-13 50.1 0.1 2.4e-13 50.1 0.1 3.6 2 2 1 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.6 PFH32011.1 - 4.5e-09 35.7 8.8 4.5e-09 35.7 8.8 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 PFH32011.1 - 4e-08 33.0 29.7 2.9e-07 30.3 10.8 4.1 4 0 0 4 4 4 2 PHD-finger C1_2 PF03107.16 PFH32011.1 - 0.01 16.1 3.0 0.01 16.1 3.0 4.3 4 0 0 4 4 4 0 C1 domain Elf4 PF07011.11 PFH32011.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Early Flowering 4 domain PHF5 PF03660.14 PFH32011.1 - 1.7 8.9 10.0 0.13 12.5 4.3 2.1 2 0 0 2 2 2 0 PHF5-like protein DZR PF12773.7 PFH32011.1 - 9.1 6.4 14.7 4.3 7.4 3.5 3.8 2 1 1 3 3 3 0 Double zinc ribbon HEAT PF02985.22 PFH32012.1 - 0.016 15.4 12.9 7.1 7.2 0.6 5.4 4 0 0 4 4 4 0 HEAT repeat Aminotran_1_2 PF00155.21 PFH32013.1 - 5.2e-41 141.0 0.0 8.9e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 PFH32013.1 - 0.00031 19.6 0.0 0.0017 17.1 0.0 1.9 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 PFH32013.1 - 0.0028 16.2 0.0 0.0051 15.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 PFH32013.1 - 0.0031 16.2 0.0 0.0046 15.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 PFH32013.1 - 0.068 12.5 0.1 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family PPDK_N PF01326.19 PFH32014.1 - 2.3e-28 99.4 0.0 1.3e-27 97.0 0.0 2.0 2 0 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CBM_20 PF00686.19 PFH32014.1 - 3.3e-16 59.0 0.1 6.7e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 Starch binding domain MutS_III PF05192.18 PFH32014.1 - 0.0052 17.0 0.6 0.011 16.0 0.6 1.5 1 0 0 1 1 1 1 MutS domain III Helo_like_N PF17111.5 PFH32014.1 - 0.01 15.2 0.2 0.024 14.0 0.2 1.6 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Clathrin PF00637.20 PFH32015.1 - 9.5e-181 592.9 34.0 4e-32 111.1 0.8 8.1 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 PFH32015.1 - 3.2e-28 97.4 1.2 1.8e-27 95.0 0.8 2.7 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 PFH32015.1 - 3.3e-08 33.4 0.0 0.00059 20.0 0.0 4.0 3 0 0 3 3 3 1 Clathrin propeller repeat Coatomer_WDAD PF04053.14 PFH32015.1 - 3.6e-08 32.9 2.2 0.0026 16.9 0.0 3.2 3 0 0 3 3 3 2 Coatomer WD associated region TPR_1 PF00515.28 PFH32015.1 - 0.00077 19.2 1.6 0.073 12.9 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 PFH32015.1 - 0.004 17.1 7.3 59 4.0 0.0 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 PFH32015.1 - 0.011 16.0 0.2 12 6.5 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat PQQ PF01011.21 PFH32015.1 - 0.062 13.3 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 PQQ enzyme repeat NinB PF05772.12 PFH32015.1 - 0.15 11.8 0.1 13 5.6 0.0 2.6 2 0 0 2 2 2 0 NinB protein TPR_2 PF07719.17 PFH32015.1 - 0.18 12.0 0.0 0.18 12.0 0.0 6.2 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 PFH32015.1 - 8.9 6.8 11.7 30 5.1 0.0 6.7 8 1 1 9 9 9 0 Tetratricopeptide repeat EMP70 PF02990.16 PFH32016.1 - 5.2e-192 639.1 7.7 7.6e-192 638.6 7.7 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 LZ3wCH PF18517.1 PFH32017.1 - 5.6e-13 48.8 0.2 3e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Mnd1 PF03962.15 PFH32017.1 - 2.1e-06 27.9 0.0 4.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Mnd1 HTH domain Spc7 PF08317.11 PFH32017.1 - 0.022 13.7 3.6 0.024 13.5 3.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3091 PF11291.8 PFH32017.1 - 0.076 13.2 1.4 0.18 12.0 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3091) DprA_WH PF17782.1 PFH32017.1 - 0.1 12.7 0.0 5.5 7.2 0.0 2.7 2 1 0 2 2 2 0 DprA winged helix domain APG6_N PF17675.1 PFH32017.1 - 0.15 12.6 7.8 0.22 12.1 7.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2357 PF09823.9 PFH32017.1 - 0.18 11.0 2.9 0.55 9.4 2.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2357) UPF0242 PF06785.11 PFH32017.1 - 0.83 9.7 5.4 1.1 9.3 5.4 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 PFH32017.1 - 1.7 9.3 5.5 62 4.2 5.5 2.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal 2OG-FeII_Oxy_3 PF13640.6 PFH32018.1 - 2.4e-09 38.0 0.0 4.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NUDIX PF00293.28 PFH32020.1 - 5.3e-05 23.3 0.0 7.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain adh_short PF00106.25 PFH32021.1 - 3.4e-28 98.5 0.0 1.4e-24 86.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PFH32021.1 - 1.4e-23 83.6 0.0 7e-19 68.3 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PFH32021.1 - 3.4e-08 33.6 0.0 6.9e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 KR domain DnaJ PF00226.31 PFH32022.1 - 1e-14 54.4 0.0 1.9e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Patched PF02460.18 PFH32023.1 - 1.9e-89 300.9 2.7 4e-41 141.0 0.0 3.0 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 PFH32023.1 - 2e-29 102.4 12.8 6.2e-28 97.6 0.1 2.3 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 PFH32023.1 - 0.025 12.2 17.0 0.026 12.2 15.4 1.6 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family MFS_1 PF07690.16 PFH32024.1 - 5.4e-05 22.3 45.1 0.00065 18.7 23.6 3.2 2 2 1 3 3 3 2 Major Facilitator Superfamily Pox_I5 PF04713.12 PFH32024.1 - 0.074 13.1 1.2 9.6 6.3 0.1 3.5 3 0 0 3 3 3 0 Poxvirus protein I5 WD40 PF00400.32 PFH32025.1 - 2.1e-29 101.1 8.6 6e-07 30.1 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH32025.1 - 1.3e-14 54.2 0.0 0.0017 18.6 0.0 5.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 PFH32025.1 - 8.3e-12 44.5 1.0 1.6e-11 43.6 1.0 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 PFH32025.1 - 4.5e-09 35.7 0.4 0.049 12.6 0.2 3.5 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PFH32025.1 - 4.2e-07 29.0 0.3 0.0066 15.1 0.1 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 PFH32025.1 - 0.048 14.2 0.3 5.9 7.5 0.0 2.7 2 0 0 2 2 2 0 PQQ-like domain WD40_like PF17005.5 PFH32025.1 - 0.088 12.1 0.0 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 WD40-like domain LisH PF08513.11 PFH32025.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 LisH PDZ_3 PF17815.1 PFH32026.1 - 2.9e-46 156.9 0.0 1.2e-44 151.7 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Trypsin_2 PF13365.6 PFH32026.1 - 7.2e-22 78.9 0.4 1.5e-21 77.8 0.4 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PFH32026.1 - 1.7e-15 57.5 0.1 2.8e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 PFH32026.1 - 7.4e-06 26.2 1.2 0.00058 20.1 0.2 2.9 2 1 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 PFH32026.1 - 0.00017 21.3 4.4 0.11 12.3 0.1 3.4 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 PFH32026.1 - 0.016 15.5 0.2 0.46 10.9 0.0 2.6 2 0 0 2 2 2 0 PDZ domain Peptidase_S46 PF10459.9 PFH32026.1 - 0.027 13.1 0.4 0.83 8.2 0.1 2.1 2 0 0 2 2 2 0 Peptidase S46 CS PF04969.16 PFH32027.1 - 0.0003 21.8 0.0 0.0029 18.6 0.0 2.4 1 1 0 1 1 1 1 CS domain UMPH-1 PF05822.12 PFH32027.1 - 0.11 12.0 1.1 0.11 12.0 0.1 1.5 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) V_ATPase_I PF01496.19 PFH32028.1 - 1e-227 758.0 0.0 1.1e-226 754.7 0.0 2.2 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family Spore_III_AB PF09548.10 PFH32028.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RANK_CRD_2 PF18278.1 PFH32029.1 - 0.044 13.9 0.6 0.096 12.8 0.6 1.5 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 DUF4531 PF15041.6 PFH32029.1 - 0.11 12.6 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4531) Pet191_N PF10203.9 PFH32029.1 - 0.11 12.8 2.3 1 9.7 2.3 2.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 F-protein PF00469.20 PFH32030.1 - 0.036 13.6 0.1 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef IMPa_N_2 PF18650.1 PFH32030.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain Peptidase_M17 PF00883.21 PFH32032.1 - 1.7e-119 398.7 2.9 1.7e-119 398.7 2.9 1.6 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 PFH32032.1 - 5.8e-07 29.4 1.7 2.3e-06 27.5 1.5 2.2 2 1 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain E3_binding PF02817.17 PFH32032.1 - 3 8.3 4.9 9.1 6.7 0.0 3.5 4 0 0 4 4 4 0 e3 binding domain RRM_8 PF11835.8 PFH32034.1 - 9.5e-11 41.8 0.0 1.3e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 RRM-like domain RRM_1 PF00076.22 PFH32034.1 - 6.6e-08 32.3 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PFH32034.1 - 2.5e-05 23.8 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PFH32034.1 - 0.0092 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 PFH32034.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 PFH32035.1 - 5.4e-30 103.6 0.2 6.1e-20 71.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 PFH32035.1 - 3.1e-18 65.4 0.1 2.8e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PFH32035.1 - 6e-08 32.4 0.1 0.00053 19.8 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF2732 PF10809.8 PFH32036.1 - 1.7 8.6 7.2 3.2 7.7 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2732) MutS_V PF00488.21 PFH32037.1 - 2.6e-70 236.3 0.1 4.1e-70 235.7 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 PFH32037.1 - 7.4e-34 117.6 2.8 3e-33 115.7 0.2 2.7 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 PFH32037.1 - 5.5e-32 110.4 0.0 1.1e-31 109.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain I AAA_25 PF13481.6 PFH32037.1 - 0.016 14.8 0.2 7 6.2 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PFH32037.1 - 0.19 11.5 0.0 0.46 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain BSP_II PF05432.11 PFH32037.1 - 1.1 8.9 41.0 2.9 7.5 41.0 1.7 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 PFH32037.1 - 1.6 6.9 46.1 4.2 5.4 46.1 1.8 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 PFH32037.1 - 1.7 7.2 66.4 1 7.9 64.3 1.5 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AP2 PF00847.20 PFH32038.1 - 5.8e-11 42.4 0.3 1.3e-10 41.4 0.3 1.6 1 0 0 1 1 1 1 AP2 domain DASH_Dam1 PF08653.10 PFH32039.1 - 3.8 7.4 5.4 13 5.6 0.3 3.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 Ligase_CoA PF00549.19 PFH32043.1 - 3.7e-26 91.8 0.1 5.5e-26 91.2 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 PFH32043.1 - 1.3e-25 89.8 0.3 4.4e-25 88.2 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 PFH32043.1 - 3.7e-11 43.0 0.0 6.4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 PFH32043.1 - 0.00056 20.4 0.1 0.0046 17.5 0.0 2.5 4 0 0 4 4 4 1 CoA binding domain ABC2_membrane PF01061.24 PFH32044.1 - 4.1e-29 101.5 19.6 4.1e-29 101.5 19.6 2.2 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PFH32044.1 - 1.8e-22 80.4 0.0 2.9e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PFH32044.1 - 6.1e-07 28.9 19.1 9.8e-07 28.2 19.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 PFH32044.1 - 3.8e-05 23.7 0.1 8.7e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 PFH32044.1 - 0.00022 21.1 0.0 0.029 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PFH32044.1 - 0.0015 18.9 0.6 0.0044 17.4 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 PFH32044.1 - 0.012 15.2 0.3 0.055 13.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PFH32044.1 - 0.015 15.6 0.6 0.05 13.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 PFH32044.1 - 0.028 14.5 0.3 0.055 13.6 0.3 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 PFH32044.1 - 0.074 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 PFH32044.1 - 0.15 11.9 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain LapA_dom PF06305.11 PFH32044.1 - 7.1 6.5 6.0 0.5 10.2 0.2 2.1 2 0 0 2 2 1 0 Lipopolysaccharide assembly protein A domain HEAT_2 PF13646.6 PFH32047.1 - 7.7e-19 67.9 13.9 3.2e-12 46.7 0.6 4.4 3 2 1 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 PFH32047.1 - 4.4e-11 42.4 15.5 0.0095 16.5 0.1 6.5 6 0 0 6 6 6 3 PBS lyase HEAT-like repeat HEAT PF02985.22 PFH32047.1 - 0.00084 19.4 5.6 0.24 11.8 0.0 5.6 6 1 0 6 6 6 1 HEAT repeat Arm PF00514.23 PFH32047.1 - 0.011 15.8 0.6 0.85 9.8 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PFH32047.1 - 0.24 11.9 9.9 3.2 8.4 0.1 5.4 4 2 1 6 6 6 0 HEAT-like repeat Voltage_CLC PF00654.20 PFH32048.1 - 1.2e-74 251.7 24.2 1.2e-74 251.7 24.2 1.7 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 PFH32048.1 - 0.025 15.0 0.1 0.091 13.2 0.0 1.9 2 0 0 2 2 2 0 CBS domain Vps51 PF08700.11 PFH32049.1 - 9.2e-05 22.4 0.0 0.00023 21.2 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 GTA_holin_3TM PF11351.8 PFH32049.1 - 0.079 13.5 0.0 0.32 11.5 0.0 2.0 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release ThiF PF00899.21 PFH32051.1 - 2.5e-95 318.5 0.1 3e-71 239.6 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 PFH32051.1 - 7.7e-77 258.6 1.3 1.2e-76 258.0 1.3 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 PFH32051.1 - 5e-26 90.7 0.1 1.3e-25 89.4 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 PFH32051.1 - 4.5e-19 69.0 0.2 1e-18 67.8 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 PFH32051.1 - 1.4e-15 57.2 0.0 3.7e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Tap-RNA_bind PF09162.10 PFH32051.1 - 0.00069 19.4 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 Tap, RNA-binding TrkA_N PF02254.18 PFH32051.1 - 0.07 13.4 0.9 3.3 8.0 0.1 3.5 4 0 0 4 4 4 0 TrkA-N domain AAA_33 PF13671.6 PFH32052.1 - 6.9e-27 94.4 0.2 1.7e-26 93.1 0.2 1.7 1 0 0 1 1 1 1 AAA domain SPRY PF00622.28 PFH32052.1 - 2.6e-11 43.7 0.0 8.4e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 SPRY domain PITH PF06201.13 PFH32053.1 - 1.2e-33 116.5 0.0 1.4e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain Tcf25 PF04910.14 PFH32055.1 - 2.6e-67 227.4 1.2 3.5e-67 227.0 1.2 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_17 PF13431.6 PFH32055.1 - 0.024 15.0 0.1 6.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 PFH32055.1 - 0.077 13.3 0.1 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MORN PF02493.20 PFH32056.1 - 0.066 13.1 1.2 0.43 10.6 0.1 3.0 4 0 0 4 4 4 0 MORN repeat Pkinase_Tyr PF07714.17 PFH32058.1 - 1.1e-11 44.6 0.0 1.6e-07 30.9 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 PFH32058.1 - 1.3e-06 28.0 0.0 4.1e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Rad50_zn_hook PF04423.14 PFH32058.1 - 3.6 7.5 5.3 0.53 10.2 0.7 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif Octopine_DH PF02317.17 PFH32059.1 - 1.8e-41 141.8 0.0 2.7e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain F420_oxidored PF03807.17 PFH32059.1 - 0.00026 21.5 0.0 0.00052 20.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 PFH32059.1 - 0.0073 15.3 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Prephenate dehydrogenase Staph_opine_DH PF10100.9 PFH32059.1 - 0.011 14.5 0.0 3.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Staphylopine dehydrogenase GFO_IDH_MocA PF01408.22 PFH32059.1 - 0.017 15.9 0.0 0.041 14.7 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold SPT2 PF08243.11 PFH32060.1 - 5.8e-11 42.9 9.3 5.8e-11 42.9 9.3 2.5 2 0 0 2 2 2 1 SPT2 chromatin protein AP2 PF00847.20 PFH32061.1 - 3.1e-07 30.5 3.2 3.7e-07 30.3 0.2 2.4 3 0 0 3 3 3 1 AP2 domain Kelch_5 PF13854.6 PFH32062.1 - 5.8e-33 112.3 3.5 1.9e-05 24.5 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Metallophos PF00149.28 PFH32062.1 - 4.9e-30 105.6 0.1 9.4e-30 104.6 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_4 PF13418.6 PFH32062.1 - 3.7e-25 87.7 6.6 2.7e-05 24.1 0.2 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 PFH32062.1 - 1e-20 72.8 12.9 2.5e-06 27.2 0.0 6.6 6 1 1 7 7 7 5 Kelch motif Kelch_3 PF13415.6 PFH32062.1 - 1.2e-19 70.1 15.2 0.00066 19.9 0.0 7.6 9 0 0 9 9 9 6 Galactose oxidase, central domain Kelch_6 PF13964.6 PFH32062.1 - 3e-16 59.0 7.3 0.02 15.2 0.0 6.8 4 2 2 6 6 6 4 Kelch motif Kelch_1 PF01344.25 PFH32062.1 - 5.2e-15 54.7 11.5 2.8e-05 23.6 0.0 7.1 6 1 1 7 7 7 2 Kelch motif RAG2 PF03089.14 PFH32062.1 - 0.00066 18.8 0.0 2.9 6.8 0.0 4.0 4 0 0 4 4 4 2 Recombination activating protein 2 CDC27 PF09507.10 PFH32062.1 - 7.4 5.8 5.3 11 5.3 5.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sortilin-Vps10 PF15902.5 PFH32063.1 - 1e-107 360.7 1.0 4.2e-57 193.9 0.0 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 PFH32063.1 - 7.6e-42 143.5 0.4 1.1e-41 143.0 0.4 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 PFH32063.1 - 8.9e-07 28.0 19.8 0.23 11.6 0.4 7.2 7 0 0 7 7 7 3 BNR/Asp-box repeat BNR_2 PF13088.6 PFH32063.1 - 0.00023 20.6 0.1 4.9 6.4 0.0 3.7 3 1 1 4 4 4 3 BNR repeat-like domain BNR_3 PF13859.6 PFH32063.1 - 0.0043 16.4 0.1 0.19 11.0 0.0 3.2 4 0 0 4 4 4 1 BNR repeat-like domain BNR_6 PF15899.5 PFH32063.1 - 0.067 13.3 1.8 0.24 11.5 0.1 3.1 3 0 0 3 3 3 0 BNR-Asp box repeat MIF PF01187.18 PFH32064.1 - 4e-19 69.0 0.0 4.4e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 PFH32064.1 - 3.8e-05 23.5 0.0 0.0031 17.4 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme Tautomerase_2 PF14552.6 PFH32064.1 - 0.0034 17.4 0.0 1.3 9.2 0.0 2.0 1 1 1 2 2 2 2 Tautomerase enzyme Cyclin_N PF00134.23 PFH32066.1 - 1.5e-07 31.2 0.0 2.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Mating_N PF12731.7 PFH32066.1 - 0.0015 18.6 1.4 0.23 11.6 0.1 2.5 2 0 0 2 2 2 2 Mating-type protein beta 1 T3SS_needle_reg PF09025.10 PFH32066.1 - 0.18 11.7 0.1 0.33 10.9 0.1 1.3 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator Proteasome PF00227.26 PFH32067.1 - 1.7e-37 128.7 0.0 2e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit s48_45 PF07422.13 PFH32068.1 - 0.039 14.5 0.1 0.051 14.1 0.1 1.2 1 0 0 1 1 1 0 Sexual stage antigen s48/45 domain Hydrolase_6 PF13344.6 PFH32070.1 - 2.5e-26 91.7 0.0 5.3e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PFH32070.1 - 1.5e-15 57.0 0.0 4.4e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 PFH32070.1 - 2.4e-07 31.0 0.0 0.0062 16.6 0.0 2.9 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PFH32070.1 - 3.6e-06 27.4 0.0 8.3e-05 23.0 0.0 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase PG_binding_2 PF08823.11 PFH32070.1 - 0.013 15.7 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain S6PP PF05116.13 PFH32070.1 - 0.17 11.4 0.1 1.3 8.5 0.0 2.2 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Reprolysin_3 PF13582.6 PFH32071.1 - 0.12 12.8 0.5 0.43 11.1 0.1 1.9 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like FleQ PF06490.11 PFH32072.1 - 0.037 14.4 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ URO-D PF01208.17 PFH32074.1 - 2.3e-105 352.6 0.0 3e-105 352.2 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PEPCK_ATP PF01293.20 PFH32075.1 - 3.2e-122 408.5 0.0 1.1e-112 377.2 0.0 2.0 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 PFH32075.1 - 0.041 14.3 0.0 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF2608 PF11019.8 PFH32076.1 - 0.18 11.3 0.4 0.61 9.5 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2608) Acetyltransf_1 PF00583.25 PFH32077.1 - 9.8e-16 58.0 0.0 1.2e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PFH32077.1 - 8.7e-11 42.1 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PFH32077.1 - 1.4e-10 41.2 0.0 1.5e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PFH32077.1 - 7.9e-07 29.0 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 PFH32077.1 - 1.8e-06 28.2 0.0 2.2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PFH32077.1 - 0.043 13.9 0.1 0.071 13.2 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pfk_N PF18468.1 PFH32077.1 - 0.14 12.6 0.1 2.5 8.6 0.1 2.2 2 0 0 2 2 2 0 Phosphofructokinase N-terminal domain yeast 3-PAP PF12578.8 PFH32078.1 - 0.23 11.2 0.9 1.2 8.8 0.1 2.4 2 0 0 2 2 2 0 Myotubularin-associated protein DUF900 PF05990.12 PFH32079.1 - 2.5e-19 69.7 0.0 4.9e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) TrbL PF04610.14 PFH32081.1 - 0.00075 19.3 0.3 0.001 18.9 0.3 1.2 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein FlgM PF04316.13 PFH32081.1 - 0.0035 17.7 0.2 0.01 16.2 0.2 1.8 1 1 0 1 1 1 1 Anti-sigma-28 factor, FlgM DUF3675 PF12428.8 PFH32081.1 - 0.012 16.2 0.5 0.017 15.7 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3675) GIT_CC PF16559.5 PFH32081.1 - 0.083 12.8 0.5 0.16 11.9 0.5 1.4 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2746 PF10874.8 PFH32081.1 - 0.16 12.4 0.2 1.9 9.0 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2746) WD40 PF00400.32 PFH32083.1 - 4.1e-23 81.2 6.7 2.4e-06 28.1 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH32083.1 - 1.8e-17 63.4 0.0 3.1e-05 24.2 0.0 5.1 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PFH32083.1 - 0.0015 18.2 0.0 0.59 9.7 0.0 2.1 1 1 0 2 2 2 2 PQQ-like domain Ge1_WD40 PF16529.5 PFH32083.1 - 0.059 12.3 0.1 1.5 7.7 0.1 2.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CHCH PF06747.13 PFH32083.1 - 0.6 10.3 3.2 3.9 7.7 0.1 3.3 3 0 0 3 3 3 0 CHCH domain RabGAP-TBC PF00566.18 PFH32084.1 - 6.2e-40 137.1 0.0 1.2e-39 136.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EMP24_GP25L PF01105.24 PFH32085.1 - 2.3e-32 112.4 0.0 2.8e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Apq12 PF12716.7 PFH32085.1 - 4.2 7.4 6.9 0.54 10.2 0.7 2.2 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis AAA_2 PF07724.14 PFH32087.1 - 3.1e-40 138.1 0.0 2.9e-32 112.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 PFH32087.1 - 6.1e-13 49.3 0.0 1.2e-05 25.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 PFH32087.1 - 5e-08 32.9 0.4 5e-08 32.9 0.4 2.2 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 PFH32087.1 - 5.9e-07 29.6 0.1 5.6e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PFH32087.1 - 5.2e-06 26.8 0.1 0.00018 21.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain MCM PF00493.23 PFH32087.1 - 6.2e-06 25.5 0.1 0.00041 19.5 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 PFH32087.1 - 1.8e-05 25.2 0.4 8.5e-05 23.0 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 PFH32087.1 - 0.0019 18.8 0.0 0.0044 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PFH32087.1 - 0.0024 17.7 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 PFH32087.1 - 0.0054 16.0 0.4 0.01 15.1 0.0 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 PFH32087.1 - 0.026 13.9 0.2 0.13 11.7 0.0 2.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 PFH32087.1 - 0.028 14.7 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PFH32087.1 - 0.03 14.0 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 PFH32087.1 - 0.067 13.5 0.0 0.17 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PFH32087.1 - 0.082 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 PFH32087.1 - 0.088 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 PFH32087.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 PFH32087.1 - 0.12 12.3 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 PFH32087.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 PFH32087.1 - 0.12 12.3 0.2 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.17 PFH32087.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 PFH32087.1 - 0.23 11.2 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Adap_comp_sub PF00928.21 PFH32088.1 - 1e-86 290.6 0.0 1.3e-86 290.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 PFH32088.1 - 5.4e-07 29.6 0.9 1e-06 28.7 0.9 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SH3_17 PF18350.1 PFH32088.1 - 0.14 12.0 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Restriction endonuclease SH3 domain BPL_LplA_LipB PF03099.19 PFH32089.1 - 0.00014 21.8 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ubiquitin PF00240.23 PFH32090.1 - 1.1e-34 118.0 0.3 1.5e-34 117.6 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 PFH32090.1 - 1.3e-30 105.0 11.9 2e-30 104.4 11.9 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 PFH32090.1 - 1.4e-16 60.1 0.4 2e-16 59.6 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PFH32090.1 - 7.7e-06 26.3 0.1 3e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 PFH32090.1 - 0.0033 17.3 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PFH32090.1 - 0.0062 16.6 0.0 0.014 15.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 PFH32090.1 - 0.0095 16.3 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 PFH32090.1 - 0.028 14.5 0.7 6.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 PFH32090.1 - 0.029 14.9 0.0 0.036 14.6 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Rdx PF10262.9 PFH32091.1 - 0.0045 17.2 0.0 0.0084 16.3 0.0 1.5 2 0 0 2 2 2 1 Rdx family Pep3_Vps18 PF05131.14 PFH32092.1 - 3.6e-26 91.8 0.0 7.1e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.9 PFH32092.1 - 0.00079 19.8 5.0 0.0017 18.8 5.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 PFH32092.1 - 0.00085 19.2 0.0 0.0074 16.2 0.0 2.3 2 1 1 3 3 3 1 Region in Clathrin and VPS Ead_Ea22 PF13935.6 PFH32092.1 - 0.14 12.8 0.9 0.68 10.6 0.8 2.1 1 1 1 2 2 2 0 Ead/Ea22-like protein zf-RING_5 PF14634.6 PFH32092.1 - 0.22 11.5 11.8 0.13 12.2 9.3 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Kelch_5 PF13854.6 PFH32093.1 - 2e-07 30.8 2.9 0.098 12.7 0.1 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 PFH32093.1 - 3.9e-06 27.0 5.0 0.003 17.8 0.0 4.7 5 0 0 5 5 5 2 Kelch motif AP2 PF00847.20 PFH32093.1 - 0.0011 19.1 0.8 0.0031 17.7 0.8 1.7 1 0 0 1 1 1 1 AP2 domain Kelch_2 PF07646.15 PFH32093.1 - 0.008 16.1 8.1 1.3 9.2 0.1 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 PFH32093.1 - 0.011 15.3 4.5 0.027 14.0 0.1 3.4 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 PFH32093.1 - 0.24 11.4 7.7 32 4.6 0.7 4.7 4 0 0 4 4 4 0 Galactose oxidase, central domain Gp_dh_C PF02800.20 PFH32095.1 - 1.9e-67 225.8 0.2 3.6e-67 224.9 0.0 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 PFH32095.1 - 1.4e-38 131.3 0.0 7.2e-38 129.0 0.0 2.2 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 PFH32095.1 - 0.018 15.1 0.6 0.13 12.4 0.0 2.6 4 0 0 4 4 4 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 PFH32095.1 - 0.06 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ras PF00071.22 PFH32096.1 - 3.8e-62 208.7 0.2 4.6e-62 208.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH32096.1 - 1.8e-35 121.7 0.0 2.9e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH32096.1 - 6.8e-14 51.7 0.1 8.8e-14 51.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PFH32096.1 - 6.3e-06 26.3 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PFH32096.1 - 9e-05 21.9 0.1 0.00018 20.9 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PFH32096.1 - 0.0002 21.0 0.1 0.0004 20.0 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 PFH32096.1 - 0.0013 18.5 0.2 0.0025 17.6 0.2 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PFH32096.1 - 0.0017 18.3 1.1 0.063 13.2 0.1 2.2 1 1 1 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 PFH32096.1 - 0.0095 16.2 0.2 0.049 13.9 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 PFH32096.1 - 0.018 15.5 0.5 0.057 13.8 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 PFH32096.1 - 0.028 13.9 0.0 0.058 12.8 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 PFH32096.1 - 0.032 14.3 0.1 0.13 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 PFH32096.1 - 0.042 13.1 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.27 PFH32096.1 - 0.12 12.9 0.2 0.28 11.7 0.2 2.0 1 1 0 1 1 1 0 ABC transporter Lactamase_B_2 PF12706.7 PFH32097.1 - 7.3e-08 32.2 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PFH32097.1 - 0.2 11.6 2.7 1.2 9.1 2.7 2.1 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily PEPCK_ATP PF01293.20 PFH32098.1 - 4e-216 718.1 0.0 4.6e-216 717.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 PFH32098.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PFH32098.1 - 0.046 13.3 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PFH32098.1 - 0.16 11.8 0.2 0.36 10.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Peptidase_C1 PF00112.23 PFH32100.1 - 4.1e-37 128.4 4.3 3.9e-30 105.6 3.0 2.8 2 1 0 2 2 2 2 Papain family cysteine protease CathepsinC_exc PF08773.11 PFH32100.1 - 2.6e-07 30.9 0.0 2.4e-05 24.6 0.0 2.9 1 1 0 1 1 1 1 Cathepsin C exclusion domain Propeptide_C1 PF08127.13 PFH32100.1 - 4.8e-05 23.2 0.0 0.001 18.9 0.0 2.7 2 0 0 2 2 2 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 PFH32100.1 - 0.048 12.4 0.1 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 Peptidase C1-like family HicB_lk_antitox PF15919.5 PFH32101.1 - 0.022 14.8 0.0 0.026 14.6 0.0 1.1 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system HSP20 PF00011.21 PFH32102.1 - 1.5e-18 66.8 0.0 2.4e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PFH32102.1 - 1e-05 25.0 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Ribosomal_L16 PF00252.18 PFH32103.1 - 0.13 12.2 1.6 0.16 11.9 1.6 1.3 1 1 0 1 1 1 0 Ribosomal protein L16p/L10e Str_synth PF03088.16 PFH32104.1 - 9.5e-18 64.1 0.0 3.1e-16 59.3 0.0 2.7 3 0 0 3 3 3 1 Strictosidine synthase SGL PF08450.12 PFH32104.1 - 5.5e-06 26.1 0.0 1.8e-05 24.4 0.0 1.9 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region IP_trans PF02121.18 PFH32105.1 - 1.9e-79 266.8 0.0 2.5e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Oxysterol_BP PF01237.18 PFH32105.1 - 3.3e-44 151.2 0.0 3e-34 118.4 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein PH PF00169.29 PFH32105.1 - 1.8e-08 34.8 0.0 3.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 PH domain RRM_1 PF00076.22 PFH32106.1 - 8e-15 54.4 0.0 1.3e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 PFH32107.1 - 1.6e-12 47.7 8.7 0.0029 18.4 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH32107.1 - 0.00035 20.8 0.2 0.0058 16.9 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CNDH2_M PF16869.5 PFH32107.1 - 0.0026 18.5 5.5 0.0075 17.0 5.5 1.8 1 0 0 1 1 1 1 PF16858 Nup160 PF11715.8 PFH32107.1 - 0.018 13.7 0.1 0.062 11.9 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 BUD22 PF09073.10 PFH32107.1 - 0.084 12.2 15.3 0.16 11.3 15.3 1.4 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 PFH32107.1 - 0.23 11.2 13.8 0.4 10.4 13.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 PFH32107.1 - 3.8 6.8 21.1 6.7 6.0 21.1 1.3 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 PFH32107.1 - 4.2 7.2 14.8 7.4 6.4 14.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spc7 PF08317.11 PFH32108.1 - 0.0022 16.9 2.7 0.0022 16.9 2.7 5.5 3 1 2 5 5 5 3 Spc7 kinetochore protein DUF3958 PF13125.6 PFH32108.1 - 0.015 15.5 1.8 0.015 15.5 1.8 6.6 7 1 1 8 8 8 0 Protein of unknown function (DUF3958) Ferritin-like PF12902.7 PFH32108.1 - 0.26 11.1 9.1 0.17 11.7 2.5 3.1 3 0 0 3 3 3 0 Ferritin-like CobA_CobO_BtuR PF02572.15 PFH32108.1 - 0.42 10.9 9.8 0.045 14.0 3.3 2.6 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Ribosomal_L19e PF01280.20 PFH32109.1 - 2.6e-62 209.1 12.7 2.6e-62 209.1 12.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e zf-RING_11 PF17123.5 PFH32110.1 - 0.0091 15.7 0.3 0.021 14.6 0.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 PFH32110.1 - 0.031 14.3 0.3 0.084 12.9 0.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 PFH32110.1 - 0.053 13.5 0.4 0.14 12.2 0.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 PFH32110.1 - 0.056 13.8 0.5 0.13 12.6 0.5 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 PFH32110.1 - 0.08 12.8 0.8 0.19 11.6 0.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PFH32110.1 - 0.13 12.6 0.2 0.33 11.3 0.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Gar1 PF04410.14 PFH32111.1 - 3.9e-17 62.4 0.0 3.9e-17 62.4 0.0 3.2 4 1 0 4 4 4 1 Gar1/Naf1 RNA binding region SpoIIE PF07228.12 PFH32112.1 - 7.5e-12 45.6 0.0 8.5e-06 25.8 0.1 2.7 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 PFH32112.1 - 0.00054 19.7 0.0 0.0067 16.1 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C AC_N PF16214.5 PFH32112.1 - 8.6 5.4 6.1 21 4.1 6.1 1.6 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region ABC2_membrane PF01061.24 PFH32116.1 - 1.4e-38 132.5 17.7 2e-38 131.9 17.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PFH32116.1 - 3.6e-26 92.3 0.1 1.5e-25 90.3 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 PFH32116.1 - 3.1e-13 49.6 10.5 4.9e-13 48.9 10.5 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PFH32116.1 - 1.8e-05 24.7 0.1 0.026 14.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PFH32116.1 - 0.00035 20.5 0.2 0.00073 19.5 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 PFH32116.1 - 0.0016 18.8 0.2 0.016 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 PFH32116.1 - 0.0033 17.1 0.1 0.0068 16.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 PFH32116.1 - 0.018 15.1 0.1 0.035 14.2 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 PFH32116.1 - 0.022 15.3 0.0 0.043 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PFH32116.1 - 0.042 14.1 0.2 0.18 12.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PFH32116.1 - 0.074 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 PFH32116.1 - 0.19 11.0 0.1 0.68 9.2 0.1 1.9 2 0 0 2 2 2 0 Zeta toxin KAP_NTPase PF07693.14 PFH32116.1 - 0.19 10.9 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain UCH PF00443.29 PFH32118.1 - 5.2e-42 144.1 0.0 8.5e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PFH32118.1 - 8.7e-14 51.8 0.0 2.9e-06 27.1 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 PFH32118.1 - 1.3e-06 28.3 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal Pkinase PF00069.25 PFH32119.1 - 1.1e-31 110.2 0.0 1.3e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32119.1 - 1.3e-23 83.7 0.0 1.5e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PFH32119.1 - 4e-10 39.0 0.0 5.8e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PFH32119.1 - 0.00016 21.7 0.0 0.045 13.7 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 PFH32119.1 - 0.05 12.6 0.1 0.072 12.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 PFH32119.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IFT43 PF15305.6 PFH32120.1 - 3.9e-06 27.1 0.9 9.4e-06 25.8 0.9 1.8 1 1 0 1 1 1 1 Intraflagellar transport protein 43 DUF3580 PF12117.8 PFH32120.1 - 0.089 13.0 0.2 0.16 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) Cullin PF00888.22 PFH32121.1 - 4.8e-140 468.1 0.0 1.6e-139 466.4 0.0 1.8 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 PFH32121.1 - 1.2e-24 86.1 1.8 3.8e-24 84.5 1.8 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain tRNA-synt_1g PF09334.11 PFH32122.1 - 4.3e-99 331.9 0.1 3.4e-56 190.7 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PFH32122.1 - 9.5e-35 119.9 1.7 4.4e-21 74.8 0.0 3.9 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 PFH32122.1 - 1.9e-15 57.0 0.0 3.8e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA_bind PF01588.20 PFH32122.1 - 1.4e-05 25.1 0.5 0.00021 21.3 0.3 2.7 2 1 0 2 2 2 1 Putative tRNA binding domain tRNA-synt_1f PF01921.18 PFH32122.1 - 1.6e-05 24.0 0.0 0.01 14.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) Anticodon_1 PF08264.13 PFH32122.1 - 0.012 15.5 0.1 0.031 14.2 0.1 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA tRNA-synt_1b PF00579.25 PFH32122.1 - 0.087 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Pro_isomerase PF00160.21 PFH32126.1 - 2.2e-50 171.0 0.0 2.6e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sld7_N PF18636.1 PFH32126.1 - 0.2 12.0 0.0 0.34 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain DnaJ PF00226.31 PFH32128.1 - 9.7e-19 67.3 0.1 2.6e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain ADH_zinc_N PF00107.26 PFH32128.1 - 1.2e-05 25.2 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PFH32128.1 - 0.09 12.7 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain CCDC53 PF10152.9 PFH32129.1 - 0.27 11.6 0.9 1.7 9.1 0.4 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Ribosomal_L12 PF00542.19 PFH32131.1 - 7.1e-18 64.7 5.8 7.1e-18 64.7 5.8 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 PFH32131.1 - 8.1e-13 47.9 6.1 2.2e-12 46.5 6.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L7/L12 dimerisation domain MCR_alpha PF02249.17 PFH32131.1 - 0.17 12.4 1.6 0.51 10.8 0.5 2.1 1 1 1 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain zf-Di19 PF05605.12 PFH32132.1 - 0.0013 18.9 4.9 0.002 18.4 3.1 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Cas_CXXC_CXXC PF09706.10 PFH32132.1 - 0.16 12.2 0.3 0.5 10.6 0.3 1.8 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-ACC PF17848.1 PFH32132.1 - 0.2 11.8 0.8 4.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_4 PF13717.6 PFH32132.1 - 0.59 10.1 4.0 8.3 6.4 4.0 2.4 1 1 0 1 1 1 0 zinc-ribbon domain Prefoldin_2 PF01920.20 PFH32133.1 - 2e-08 34.1 6.4 7.9e-08 32.2 6.4 1.7 1 1 0 1 1 1 1 Prefoldin subunit SlyX PF04102.12 PFH32133.1 - 0.00011 22.7 0.9 0.041 14.5 0.1 2.2 2 0 0 2 2 2 1 SlyX OmpH PF03938.14 PFH32133.1 - 0.00078 19.8 1.9 0.0029 17.9 0.4 1.9 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) Filament PF00038.21 PFH32133.1 - 0.0018 17.9 4.0 0.31 10.6 0.1 2.0 2 0 0 2 2 2 2 Intermediate filament protein HIP1_clath_bdg PF16515.5 PFH32133.1 - 0.0037 17.8 4.0 0.0066 17.0 0.9 2.0 2 0 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Tropomyosin_1 PF12718.7 PFH32133.1 - 0.0081 16.3 9.6 0.018 15.2 9.6 1.5 1 1 0 1 1 1 1 Tropomyosin like TolA_bind_tri PF16331.5 PFH32133.1 - 0.0082 16.2 4.0 1 9.5 0.1 2.1 2 0 0 2 2 2 2 TolA binding protein trimerisation ADIP PF11559.8 PFH32133.1 - 0.009 16.1 1.9 0.11 12.5 0.2 2.0 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding STAT_alpha PF01017.20 PFH32133.1 - 0.01 15.7 0.7 0.015 15.2 0.7 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain SKA2 PF16740.5 PFH32133.1 - 0.013 15.3 0.8 4.5 7.1 0.1 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Toxin-deaminase PF14424.6 PFH32133.1 - 0.016 15.3 0.2 0.021 14.9 0.2 1.2 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases KxDL PF10241.9 PFH32133.1 - 0.021 15.1 2.6 0.049 13.9 1.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein PI3K_P85_iSH2 PF16454.5 PFH32133.1 - 0.021 14.4 3.4 0.082 12.5 0.7 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FAM184 PF15665.5 PFH32133.1 - 0.025 14.3 4.9 1.7 8.4 0.2 2.0 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B HR1 PF02185.16 PFH32133.1 - 0.032 14.3 3.2 2.6 8.2 0.7 2.3 2 0 0 2 2 2 0 Hr1 repeat Snapin_Pallidin PF14712.6 PFH32133.1 - 0.033 14.6 2.2 2.1 8.8 0.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Sec2p PF06428.11 PFH32133.1 - 0.034 14.1 5.0 0.24 11.4 1.3 2.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DivIC PF04977.15 PFH32133.1 - 0.05 13.4 3.2 2.3 8.0 0.7 2.2 2 0 0 2 2 2 0 Septum formation initiator RmuC PF02646.16 PFH32133.1 - 0.058 12.5 2.5 0.77 8.8 1.5 2.0 1 1 1 2 2 2 0 RmuC family DUF5082 PF16888.5 PFH32133.1 - 0.088 13.1 2.3 3.3 8.0 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Com_YlbF PF06133.11 PFH32133.1 - 0.11 13.1 5.2 0.49 11.0 0.1 2.1 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA V_ATPase_I PF01496.19 PFH32133.1 - 0.11 10.4 1.6 0.13 10.1 1.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Swi5 PF07061.11 PFH32133.1 - 0.12 12.5 2.8 5.7 7.1 2.2 2.2 2 0 0 2 2 2 0 Swi5 IFT57 PF10498.9 PFH32133.1 - 0.13 11.3 5.5 0.079 11.9 2.6 1.8 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 FUSC PF04632.12 PFH32133.1 - 0.14 10.7 0.0 0.16 10.5 0.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.9 PFH32133.1 - 0.15 12.1 11.2 3.8 7.5 6.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 PFH32133.1 - 0.28 11.7 7.3 3.2 8.3 0.1 2.3 2 0 0 2 2 2 0 Cell division protein ZapB DUF745 PF05335.13 PFH32133.1 - 0.41 10.3 1.8 0.64 9.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Spc24 PF08286.11 PFH32133.1 - 0.44 10.8 6.7 47 4.3 6.7 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4140 PF13600.6 PFH32133.1 - 0.54 10.7 6.6 2 8.9 0.4 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 PFH32133.1 - 0.58 10.6 5.8 9 6.8 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.17 PFH32133.1 - 0.59 10.1 9.4 3.4 7.6 0.2 2.2 1 1 1 2 2 2 0 Prefoldin subunit Fez1 PF06818.15 PFH32133.1 - 0.8 10.1 8.5 3 8.3 3.9 1.9 1 1 1 2 2 2 0 Fez1 AKNA PF12443.8 PFH32133.1 - 0.97 10.1 5.5 31 5.3 0.1 2.7 1 1 2 3 3 3 0 AT-hook-containing transcription factor DUF4446 PF14584.6 PFH32133.1 - 1.3 9.0 4.6 2.4 8.1 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF641 PF04859.12 PFH32133.1 - 1.5 9.2 5.7 2.9 8.2 5.4 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 PFH32133.1 - 1.6 7.9 3.2 2.4 7.3 3.2 1.4 1 1 0 1 1 1 0 TMPIT-like protein KELK PF15796.5 PFH32133.1 - 1.9 9.0 14.9 0.8 10.2 0.8 2.2 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase bZIP_1 PF00170.21 PFH32133.1 - 2.8 8.1 9.1 4.9 7.3 0.1 2.2 2 0 0 2 2 2 0 bZIP transcription factor RAP PF08373.10 PFH32134.1 - 6.2e-07 29.4 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 RAP domain GREB1 PF15782.5 PFH32134.1 - 0.07 10.2 0.6 0.11 9.6 0.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TPR_2 PF07719.17 PFH32135.1 - 1e-14 53.3 11.0 0.00017 21.4 0.8 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 PFH32135.1 - 1.2e-14 53.4 0.3 0.00021 21.0 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 PFH32135.1 - 9.6e-09 35.8 4.3 9.7e-07 29.3 0.1 7.2 7 1 1 8 8 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 PFH32135.1 - 2e-08 33.8 0.2 0.057 13.7 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 PFH32135.1 - 6.7e-08 32.9 7.2 0.011 16.2 0.0 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 PFH32135.1 - 1.2e-07 31.3 0.0 0.0011 18.6 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_9 PF13371.6 PFH32135.1 - 2.8e-06 27.4 0.2 2.8e-06 27.4 0.2 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH32135.1 - 1.3e-05 25.3 3.1 2.1e-05 24.7 0.5 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PFH32135.1 - 8.8e-05 22.3 4.8 2.2 8.5 0.1 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 PFH32135.1 - 0.0017 18.6 8.8 0.062 13.6 0.7 4.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 PFH32135.1 - 0.0028 17.9 5.0 2.4 8.7 0.0 4.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 PFH32135.1 - 0.0065 17.0 0.1 4.4 8.1 0.0 4.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PFH32135.1 - 0.076 13.9 0.1 0.076 13.9 0.1 7.5 6 1 2 8 8 7 0 Tetratricopeptide repeat Thioredoxin_8 PF13905.6 PFH32136.1 - 1.3e-21 76.7 0.0 1.9e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 PFH32136.1 - 1.3e-05 25.6 0.0 2.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 PFH32136.1 - 0.0005 20.0 0.0 0.00082 19.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 PFH32136.1 - 0.011 15.7 0.1 0.38 10.8 0.1 2.2 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_7 PF13899.6 PFH32136.1 - 0.043 14.0 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 PFH32136.1 - 0.22 11.2 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Redoxin Guanylate_cyc PF00211.20 PFH32137.1 - 6.1e-18 65.1 0.0 1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.31 PFH32137.1 - 3.5e-05 23.2 0.1 6.6e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Ion transport protein L51_S25_CI-B8 PF05047.16 PFH32139.1 - 0.013 15.4 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U79_P34 PF03064.16 PFH32140.1 - 0.15 11.4 8.7 0.24 10.7 8.7 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2052 PF09747.9 PFH32140.1 - 0.3 11.2 11.3 0.61 10.2 11.3 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pox_Ag35 PF03286.14 PFH32140.1 - 0.59 9.9 11.6 1.4 8.7 11.6 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RR_TM4-6 PF06459.12 PFH32140.1 - 0.78 9.5 13.7 1.5 8.5 13.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 PFH32140.1 - 3.3 6.4 11.2 6.6 5.4 11.2 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.13 PFH32140.1 - 8 5.1 8.4 13 4.4 8.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4746 PF15928.5 PFH32140.1 - 9.3 5.6 12.1 16 4.8 12.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) End3 PF12761.7 PFH32141.1 - 0.0093 16.2 9.9 0.024 14.8 9.9 1.7 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 DUF1117 PF06547.12 PFH32141.1 - 0.096 13.2 1.1 1.1 9.9 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) DUF641 PF04859.12 PFH32141.1 - 0.13 12.6 6.8 0.28 11.5 6.1 1.9 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 PFH32141.1 - 1.5 7.6 9.1 3.4 6.5 9.1 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein PriCT_1 PF08708.11 PFH32142.1 - 0.057 13.2 0.2 0.18 11.6 0.2 1.8 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) TFIIA PF03153.13 PFH32142.1 - 0.61 10.0 8.7 0.17 11.8 2.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 PFH32143.1 - 3.6e-12 46.2 0.0 5.2e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PFH32143.1 - 2.7e-11 43.3 0.0 6.4e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like HOOK PF05622.12 PFH32144.1 - 6.2e-16 57.7 85.6 4.2e-15 55.0 83.8 2.6 2 1 0 2 2 2 1 HOOK protein DUF4201 PF13870.6 PFH32144.1 - 0.0069 16.1 13.3 0.0069 16.1 13.3 7.0 1 1 7 8 8 8 1 Domain of unknown function (DUF4201) DUF641 PF04859.12 PFH32144.1 - 0.0078 16.5 5.1 0.0078 16.5 5.1 6.7 2 1 4 6 6 6 1 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 PFH32144.1 - 0.0081 16.3 3.4 0.0081 16.3 3.4 6.5 2 1 3 6 6 6 1 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 PFH32144.1 - 0.015 15.9 9.8 0.015 15.9 9.8 6.8 5 1 0 6 6 6 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Nup54_57_C PF18570.1 PFH32144.1 - 2.1 8.0 14.6 1.6 8.4 1.6 5.1 4 0 0 4 4 4 0 NUP57/Nup54 C-terminal domain RTT107_BRCT_5 PF16770.5 PFH32144.1 - 4.9 7.1 8.8 2.9 7.8 2.6 3.0 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Adaptin_N PF01602.20 PFH32145.1 - 7.7e-76 255.7 0.0 9.2e-43 146.6 2.2 2.8 3 0 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 PFH32145.1 - 2.2e-13 50.6 0.6 1.2e-11 44.9 0.7 2.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PFH32145.1 - 0.0011 19.3 1.3 0.0011 19.3 1.3 6.3 8 0 0 8 8 8 1 HEAT repeats HEAT PF02985.22 PFH32145.1 - 0.0062 16.7 24.3 0.61 10.5 0.2 7.6 8 0 0 8 8 8 2 HEAT repeat Arm PF00514.23 PFH32145.1 - 1 9.5 9.7 5.2 7.3 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat E1-E2_ATPase PF00122.20 PFH32146.1 - 1.1e-15 57.6 0.0 1.1e-15 57.6 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 PFH32146.1 - 6.2e-14 52.8 0.0 1.8e-05 25.2 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PFH32146.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Plasmid_stab_B PF10784.9 PFH32146.1 - 0.12 12.3 0.4 0.55 10.1 0.1 2.2 2 0 0 2 2 2 0 Plasmid stability protein MAP2_projctn PF08377.10 PFH32147.1 - 0.13 10.3 0.0 0.19 9.7 0.0 1.1 1 0 0 1 1 1 0 MAP2/Tau projection domain Pkinase PF00069.25 PFH32148.1 - 7.3e-08 32.1 0.0 0.0012 18.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32148.1 - 0.0031 16.8 0.0 0.23 10.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 PFH32148.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arm PF00514.23 PFH32149.1 - 1.3e-14 53.7 1.3 0.0055 16.7 0.1 6.3 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PFH32149.1 - 6.3e-07 29.7 2.3 0.0029 18.0 0.3 4.3 2 2 2 4 4 4 2 HEAT repeats KAP PF05804.12 PFH32149.1 - 0.012 13.8 0.1 0.021 13.0 0.1 1.3 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) RecR PF02132.15 PFH32149.1 - 0.046 13.3 1.0 0.4 10.3 0.7 2.4 2 0 0 2 2 2 0 RecR protein V-ATPase_H_N PF03224.14 PFH32151.1 - 8.8e-05 21.9 0.0 0.00023 20.6 0.0 1.7 1 0 0 1 1 1 1 V-ATPase subunit H Speriolin_N PF15058.6 PFH32151.1 - 0.3 11.1 0.1 0.3 11.1 0.1 2.1 2 1 0 2 2 2 0 Speriolin N terminus HEAT_2 PF13646.6 PFH32151.1 - 2.5 8.6 5.8 35 4.9 0.1 4.8 4 1 2 6 6 6 0 HEAT repeats STAT_int PF02865.17 PFH32152.1 - 0.069 13.6 0.4 0.16 12.4 0.4 1.5 1 0 0 1 1 1 0 STAT protein, protein interaction domain CwfJ_C_1 PF04677.15 PFH32154.1 - 1.4e-26 92.8 0.0 2.3e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.22 PFH32154.1 - 2.4e-09 36.9 0.0 4.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CwfJ_C_2 PF04676.14 PFH32154.1 - 0.012 16.5 0.0 0.024 15.5 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 2 RRM_7 PF16367.5 PFH32154.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif IGR PF09597.10 PFH32156.1 - 4.4e-06 26.7 0.0 1.3e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 IGR protein motif SANT_DAMP1_like PF16282.5 PFH32156.1 - 0.021 15.0 1.3 0.051 13.8 1.3 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 PFH32156.1 - 0.027 14.7 0.4 0.072 13.4 0.4 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain HHH_2 PF12826.7 PFH32156.1 - 0.034 14.3 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH PF00633.23 PFH32156.1 - 0.042 13.7 0.0 0.41 10.6 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 PFH32156.1 - 0.12 13.0 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain LysM PF01476.20 PFH32156.1 - 0.16 12.0 0.1 0.39 10.8 0.1 1.6 2 0 0 2 2 2 0 LysM domain Plectin PF00681.20 PFH32160.1 - 0.15 12.0 0.1 0.37 10.7 0.1 1.7 1 0 0 1 1 1 0 Plectin repeat Cnd2 PF05786.14 PFH32162.1 - 1.5e-23 83.4 18.7 5e-18 65.2 2.1 4.4 4 1 0 4 4 4 3 Condensin complex subunit 2 CNDH2_N PF06278.11 PFH32162.1 - 0.03 14.5 0.5 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal ABC2_membrane PF01061.24 PFH32163.1 - 2.8e-22 79.2 20.6 2.8e-22 79.2 20.6 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PFH32163.1 - 1.6e-19 70.8 0.0 2.7e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PFH32163.1 - 1.5e-05 24.3 9.7 2.1e-05 23.8 9.7 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 PFH32163.1 - 0.00031 21.2 0.0 0.0013 19.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 PFH32163.1 - 0.00033 20.3 0.0 0.036 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PFH32163.1 - 0.001 19.4 0.0 0.003 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PFH32163.1 - 0.0023 17.9 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 PFH32163.1 - 0.011 15.9 0.1 0.095 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 PFH32163.1 - 0.031 14.1 0.0 1.7 8.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 PFH32163.1 - 0.05 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PFH32163.1 - 0.066 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KR PF08659.10 PFH32163.1 - 0.088 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 KR domain ATPase_2 PF01637.18 PFH32163.1 - 0.09 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 PFH32163.1 - 0.18 12.2 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 PFH32163.1 - 0.21 12.1 0.0 0.38 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 PFH32163.1 - 0.28 11.6 0.0 0.28 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF4719 PF15843.5 PFH32163.1 - 1.5 8.9 5.0 2.6 8.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) DUF866 PF05907.13 PFH32164.1 - 9.6e-44 149.0 0.1 1.1e-43 148.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Yos1 PF08571.10 PFH32165.1 - 1.6e-17 63.5 1.4 1.9e-17 63.3 1.4 1.1 1 0 0 1 1 1 1 Yos1-like RTP1_C2 PF10304.9 PFH32166.1 - 0.056 13.1 0.3 0.17 11.6 0.3 1.8 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 GCP_C_terminal PF04130.13 PFH32166.1 - 0.065 12.7 0.4 1.1 8.6 0.3 3.0 2 1 0 2 2 2 0 Gamma tubulin complex component C-terminal DUF3272 PF11676.8 PFH32166.1 - 0.12 12.7 0.4 0.24 11.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3272) TIP49 PF06068.13 PFH32168.1 - 9.2e-156 518.4 0.1 1.2e-155 518.1 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 PFH32168.1 - 6.2e-24 83.9 1.5 1.5e-23 82.7 1.5 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 PFH32168.1 - 2.4e-12 47.4 0.3 7.5e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PFH32168.1 - 2.8e-08 33.7 0.2 6.4e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PFH32168.1 - 5.6e-07 30.1 0.3 5.3e-06 26.9 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 PFH32168.1 - 8.8e-06 25.2 0.1 1.5e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 PFH32168.1 - 1.2e-05 25.6 0.0 0.2 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 PFH32168.1 - 1.2e-05 24.7 0.1 3.7e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.14 PFH32168.1 - 1.3e-05 25.2 0.1 0.019 15.0 0.0 2.9 2 1 1 3 3 3 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PFH32168.1 - 5.7e-05 22.6 0.4 0.0039 16.6 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 PFH32168.1 - 0.00016 22.1 0.4 0.00042 20.7 0.1 2.0 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 PFH32168.1 - 0.00031 20.7 0.0 0.00066 19.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 PFH32168.1 - 0.00036 20.9 0.8 0.014 15.7 0.8 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 PFH32168.1 - 0.00072 19.2 0.1 0.0045 16.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 PFH32168.1 - 0.001 18.8 0.0 0.79 9.4 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_33 PF13671.6 PFH32168.1 - 0.0035 17.5 0.1 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PFH32168.1 - 0.006 17.1 0.0 0.03 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PFH32168.1 - 0.015 14.8 0.2 0.069 12.7 0.0 2.1 2 1 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 PFH32168.1 - 0.028 13.7 0.0 0.055 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.10 PFH32168.1 - 0.03 13.8 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 PFH32168.1 - 0.036 13.9 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase ATPase PF06745.13 PFH32168.1 - 0.045 13.1 2.2 0.055 12.8 0.1 2.2 3 0 0 3 3 3 0 KaiC ResIII PF04851.15 PFH32168.1 - 0.06 13.3 0.1 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CPT PF07931.12 PFH32168.1 - 0.064 13.1 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TsaE PF02367.17 PFH32168.1 - 0.081 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 PFH32168.1 - 0.12 12.1 0.1 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.22 PFH32168.1 - 0.14 11.3 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 PFH32168.1 - 0.19 12.1 0.0 1 9.8 0.0 2.2 3 0 0 3 3 2 0 RNA helicase TMEM72 PF16054.5 PFH32169.1 - 0.031 14.0 1.5 0.035 13.8 1.5 1.1 1 0 0 1 1 1 0 Transmembrane protein family 72 DUF5580 PF17743.1 PFH32171.1 - 0.034 12.7 0.6 0.052 12.1 0.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) HEPN_Swt1 PF18731.1 PFH32172.1 - 2.4 8.5 7.0 0.38 11.1 1.0 2.6 2 1 0 2 2 2 0 Swt1-like HEPN Pyr_redox_2 PF07992.14 PFH32173.1 - 3.9e-43 147.8 0.0 5.3e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PFH32173.1 - 2.9e-10 40.5 0.0 9.7e-09 35.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PFH32173.1 - 0.035 13.7 0.0 0.98 8.9 0.0 2.5 1 1 1 2 2 2 0 FAD dependent oxidoreductase Mg_trans_NIPA PF05653.14 PFH32174.1 - 1.1e-21 77.2 17.0 2.4e-21 76.1 17.0 1.4 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 PFH32174.1 - 0.00026 21.2 28.5 0.00061 20.0 5.4 2.6 3 0 0 3 3 3 2 EamA-like transporter family TMEM234 PF10639.9 PFH32174.1 - 0.0025 17.8 5.8 0.0062 16.6 0.7 2.3 2 0 0 2 2 2 1 Putative transmembrane family 234 DUF3337 PF11816.8 PFH32175.1 - 0.0097 15.8 0.5 0.018 14.9 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) UCR_14kD PF02271.16 PFH32176.1 - 1e-20 73.5 0.1 1.8e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Asparaginase PF00710.20 PFH32177.1 - 4.7e-55 186.1 0.0 7.5e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 PFH32177.1 - 4.7e-21 75.1 0.0 1.7e-20 73.4 0.0 1.9 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain DNA_pol_B_thumb PF14791.6 PFH32178.1 - 3.5e-18 65.5 0.8 1.6e-10 41.0 0.0 2.7 2 0 0 2 2 2 2 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 PFH32178.1 - 2.6e-14 53.4 0.1 1.4e-10 41.3 0.0 3.4 3 0 0 3 3 3 2 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 PFH32178.1 - 4.7e-09 35.9 0.0 1.2e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 Fingers domain of DNA polymerase lambda Cdd1 PF11731.8 PFH32178.1 - 0.0013 18.9 0.0 0.0041 17.3 0.0 1.8 2 0 0 2 2 2 1 Pathogenicity locus HHH_8 PF14716.6 PFH32178.1 - 0.0074 16.6 0.4 3.3 8.1 0.1 3.1 3 0 0 3 3 3 1 Helix-hairpin-helix domain DUF4332 PF14229.6 PFH32178.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Ribosomal_L16 PF00252.18 PFH32179.1 - 4.2e-42 143.3 0.1 5.5e-42 142.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e SMC_N PF02463.19 PFH32181.1 - 4.5e-42 144.0 0.0 7.1e-40 136.8 0.0 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PFH32181.1 - 3.9e-21 75.5 0.0 1.8e-20 73.4 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 PFH32181.1 - 1.5e-10 41.4 4.8 1.5e-05 24.9 0.4 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 PFH32181.1 - 5.8e-05 23.7 21.6 5.8e-05 23.7 21.6 7.0 4 3 1 5 5 5 1 AAA domain AAA_29 PF13555.6 PFH32181.1 - 0.00015 21.4 0.0 0.00035 20.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 PFH32181.1 - 0.0066 16.2 0.0 0.0066 16.2 0.0 3.4 3 2 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 PFH32181.1 - 0.007 16.8 2.5 0.23 11.9 0.0 4.0 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PFH32181.1 - 0.4 11.2 0.0 0.4 11.2 0.0 5.4 6 1 0 6 6 6 0 ABC transporter HSCB_C PF07743.13 PFH32182.1 - 1.1e-11 45.0 6.4 1.1e-11 45.0 6.4 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 PFH32182.1 - 0.00019 21.5 1.2 0.00019 21.5 1.2 1.7 2 0 0 2 2 2 1 DnaJ domain RNA_POL_M_15KD PF02150.16 PFH32182.1 - 0.045 13.6 0.1 0.045 13.6 0.1 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit DZR PF12773.7 PFH32182.1 - 0.093 12.8 4.6 0.058 13.4 2.3 1.9 2 0 0 2 2 2 0 Double zinc ribbon TetR_C_34 PF17929.1 PFH32182.1 - 0.14 12.3 0.2 0.34 11.0 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain zf-ribbon_3 PF13248.6 PFH32182.1 - 0.15 11.5 7.5 0.079 12.4 4.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 PFH32182.1 - 7.2 6.2 8.6 2.5 7.7 0.4 2.5 1 1 1 2 2 2 0 TFIIB zinc-binding AP_endonuc_2 PF01261.24 PFH32183.1 - 3.5e-33 114.8 0.0 4.8e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PRMT5_TIM PF17285.2 PFH32183.1 - 0.014 14.6 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 PRMT5 TIM barrel domain Pan3_PK PF18101.1 PFH32183.1 - 0.034 14.1 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Pan3 Pseudokinase domain Radical_SAM PF04055.21 PFH32185.1 - 4.1e-07 30.5 0.0 1.3e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily NAP PF00956.18 PFH32186.1 - 4.3e-22 78.6 1.7 3.6e-17 62.4 0.0 2.4 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) NOA36 PF06524.12 PFH32186.1 - 0.68 9.2 10.4 0.91 8.8 10.4 1.3 1 0 0 1 1 1 0 NOA36 protein Evr1_Alr PF04777.13 PFH32187.1 - 1.8e-20 73.3 1.0 3.1e-20 72.5 1.0 1.4 1 0 0 1 1 1 1 Erv1 / Alr family Ribosomal_L21p PF00829.21 PFH32188.1 - 2e-19 69.7 0.0 3.7e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein WD40 PF00400.32 PFH32189.1 - 2.2e-05 25.1 5.1 0.095 13.6 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH32189.1 - 0.00021 21.5 0.0 0.011 16.1 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PFH32189.1 - 0.0027 16.7 0.1 0.1 11.5 0.0 2.2 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Methyltransf_31 PF13847.6 PFH32191.1 - 2.1e-09 37.4 0.0 2.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH32191.1 - 7.2e-09 36.2 0.0 1.1e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PFH32191.1 - 6.8e-06 26.6 0.0 1.1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PFH32191.1 - 9e-05 22.4 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 PFH32191.1 - 9.9e-05 22.1 0.1 0.00026 20.7 0.1 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 DOT1 PF08123.13 PFH32191.1 - 0.00013 21.6 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 RrnaAD PF00398.20 PFH32191.1 - 0.00014 21.0 0.0 0.00019 20.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 PFH32191.1 - 0.00029 20.4 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 PFH32191.1 - 0.00048 19.6 0.1 0.00062 19.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 PFH32191.1 - 0.00053 20.7 0.0 0.00083 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PFH32191.1 - 0.00068 19.0 0.0 0.00096 18.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 PFH32191.1 - 0.0011 18.6 0.1 0.0015 18.1 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 PFH32191.1 - 0.0014 18.6 0.1 0.0019 18.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 PFH32191.1 - 0.0034 16.7 0.0 0.0042 16.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 PFH32191.1 - 0.005 16.6 0.0 0.0073 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 PFH32191.1 - 0.01 15.8 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 PFH32191.1 - 0.016 15.0 0.0 0.021 14.7 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_4 PF02390.17 PFH32191.1 - 0.09 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.14 PFH32191.1 - 0.098 12.1 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB Pox_MCEL PF03291.16 PFH32191.1 - 0.22 10.6 0.0 0.29 10.2 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme Macoilin PF09726.9 PFH32192.1 - 0.015 13.9 11.8 0.022 13.3 11.8 1.3 1 0 0 1 1 1 0 Macoilin family Ank_2 PF12796.7 PFH32194.1 - 0.026 15.1 0.0 0.13 12.9 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) TAFII55_N PF04658.13 PFH32194.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 TAFII55 protein conserved region ORC6 PF05460.13 PFH32194.1 - 3.1 7.0 6.5 2.2 7.4 4.7 1.4 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Nucleoside_tran PF01733.18 PFH32195.1 - 2.3e-19 69.9 12.1 4.3e-15 55.9 4.4 2.4 3 0 0 3 3 3 2 Nucleoside transporter Methyltr_RsmB-F PF01189.17 PFH32196.1 - 7e-65 218.4 0.0 1.2e-64 217.6 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 PFH32196.1 - 1.5e-07 31.8 0.1 5e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF PCMT PF01135.19 PFH32196.1 - 0.024 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 PFH32196.1 - 0.054 13.6 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase UCH PF00443.29 PFH32197.1 - 4.8e-18 65.6 0.0 2e-14 53.7 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PFH32197.1 - 6.8e-05 22.6 0.0 0.00065 19.4 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Mqo PF06039.15 PFH32199.1 - 4.7e-20 71.6 0.0 8.2e-20 70.8 0.0 1.3 1 1 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) DAO PF01266.24 PFH32199.1 - 6.6e-17 62.1 0.0 1e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 PFH32199.1 - 9.4e-05 21.8 0.2 0.00031 20.1 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PFH32199.1 - 0.0023 17.9 0.1 0.64 10.0 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 PFH32199.1 - 0.0046 16.2 0.0 0.43 9.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PFH32199.1 - 0.03 14.9 0.3 1.5 9.4 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PFH32199.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Xpo1 PF08389.12 PFH32201.1 - 0.0038 17.3 0.5 0.024 14.7 0.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein Aldedh PF00171.22 PFH32202.1 - 3e-37 128.2 0.0 4.3e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 PFH32203.1 - 1.9e-44 152.0 0.0 1.5e-43 149.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32203.1 - 6.8e-29 100.9 0.0 1.1e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Response_reg PF00072.24 PFH32203.1 - 6.3e-06 26.3 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase_fungal PF17667.1 PFH32203.1 - 0.0018 17.1 0.1 0.0036 16.1 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PFH32203.1 - 0.0058 15.6 0.1 0.0099 14.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain LETM1 PF07766.13 PFH32205.1 - 1.1e-80 270.8 6.7 1.1e-80 270.8 6.7 2.2 3 0 0 3 3 3 1 LETM1-like protein HTH_26 PF13443.6 PFH32205.1 - 0.09 13.2 0.3 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain ZapB PF06005.12 PFH32205.1 - 0.24 11.9 0.0 0.24 11.9 0.0 5.9 5 2 1 6 6 6 0 Cell division protein ZapB Glycos_transf_2 PF00535.26 PFH32206.1 - 2.2e-13 50.4 0.0 1.6e-06 28.0 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PFH32206.1 - 0.00071 19.5 0.0 0.17 11.8 0.0 3.1 3 0 0 3 3 3 1 Glycosyltransferase like family 2 BUD22 PF09073.10 PFH32206.1 - 0.031 13.6 2.7 0.045 13.1 2.7 1.1 1 0 0 1 1 1 0 BUD22 HSP90 PF00183.18 PFH32207.1 - 6e-234 777.7 30.5 7.7e-234 777.4 30.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 PFH32207.1 - 2.4e-14 53.8 0.1 4.3e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PFH32207.1 - 2.7e-12 46.7 0.1 6.7e-12 45.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 PFH32207.1 - 0.0078 16.2 1.0 0.018 15.0 0.3 2.0 2 0 0 2 2 2 1 Tumour suppressor protein ATG101 PF07855.12 PFH32207.1 - 0.041 13.9 1.8 27 4.7 0.0 2.6 2 0 0 2 2 2 0 Autophagy-related protein 101 RNA_pol_Rpc4 PF05132.14 PFH32207.1 - 2.2 8.7 7.5 4.5 7.7 7.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4477 PF14780.6 PFH32208.1 - 5.2e-05 23.0 0.5 0.0056 16.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4477) tRNA-synt_1b PF00579.25 PFH32209.1 - 4.7e-16 59.0 0.0 4.4e-15 55.8 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Nkap_C PF06047.11 PFH32210.1 - 1.4e-48 163.2 2.8 1.4e-48 163.2 2.8 5.1 5 0 0 5 5 5 1 NF-kappa-B-activating protein C-terminal domain UBX PF00789.20 PFH32211.1 - 2e-10 40.7 0.0 3.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain Med19 PF10278.9 PFH32211.1 - 0.056 13.4 2.9 0.083 12.8 2.9 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF3301 PF11743.8 PFH32211.1 - 0.19 11.4 0.2 0.19 11.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) CDC45 PF02724.14 PFH32211.1 - 0.54 8.5 9.3 0.72 8.1 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 PFH32211.1 - 2.5 6.1 9.0 3.8 5.5 9.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 PFH32211.1 - 9.1 4.9 9.4 14 4.3 9.4 1.2 1 0 0 1 1 1 0 Presenilin SET PF00856.28 PFH32213.1 - 1.5e-07 32.0 0.0 1e-06 29.2 0.0 2.5 2 1 0 2 2 2 1 SET domain ADK PF00406.22 PFH32214.1 - 2.7e-42 144.4 0.0 3.4e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PFH32214.1 - 7.6e-20 71.7 0.0 1.7e-19 70.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 PFH32214.1 - 5.2e-06 26.9 0.7 0.015 15.6 0.0 2.5 3 0 0 3 3 3 2 Hydin Adenylate kinase-like domain ADK_lid PF05191.14 PFH32214.1 - 0.00011 22.1 1.4 0.00023 21.0 1.4 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 PFH32214.1 - 0.0018 18.5 0.0 0.0039 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PFH32214.1 - 0.0037 17.8 0.0 0.0067 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PFH32214.1 - 0.055 12.7 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin EMG1 PF03587.14 PFH32215.1 - 3.3e-13 49.7 0.1 5.3e-06 26.2 0.0 3.7 3 1 0 3 3 3 2 EMG1/NEP1 methyltransferase DUF4602 PF15375.6 PFH32217.1 - 8.8e-08 32.6 11.7 8.8e-08 32.6 11.7 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4602) Arf PF00025.21 PFH32218.1 - 3.7e-21 75.3 0.0 6.4e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family CDH PF02611.15 PFH32218.1 - 0.11 12.1 0.1 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 CDP-diacylglycerol pyrophosphatase PhoLip_ATPase_C PF16212.5 PFH32221.1 - 4.5e-38 131.4 20.5 9.4e-38 130.4 20.5 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PFH32221.1 - 1.7e-17 62.8 0.1 7.6e-17 60.8 0.0 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 PFH32221.1 - 5e-08 32.7 0.0 5e-08 32.7 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 PFH32221.1 - 9.5e-08 32.6 1.6 0.00085 19.7 0.1 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PFH32221.1 - 8.9e-06 25.7 0.0 3.5e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PFH32221.1 - 0.031 14.0 0.0 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Tom5 PF10642.9 PFH32222.1 - 0.32 11.1 1.9 0.69 10.0 1.9 1.7 1 1 0 1 1 1 0 Mitochondrial import receptor subunit or translocase GRIP PF01465.20 PFH32223.1 - 2.3e-10 40.2 0.1 5.5e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 GRIP domain DUF1043 PF06295.12 PFH32223.1 - 0.07 13.1 0.3 0.07 13.1 0.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1043) zf-FPG_IleRS PF06827.14 PFH32223.1 - 0.16 11.9 0.3 0.44 10.5 0.1 1.9 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Stk19 PF10494.9 PFH32224.1 - 2e-07 31.0 0.7 4.9e-05 23.1 0.1 2.7 3 1 0 3 3 3 2 Serine-threonine protein kinase 19 CAP PF00188.26 PFH32225.1 - 0.044 14.6 0.1 0.072 13.9 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family PUL PF08324.11 PFH32226.1 - 2.6e-30 105.6 0.7 4.6e-30 104.8 0.7 1.4 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 PFH32226.1 - 3.9e-30 104.4 0.0 6.7e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 PFH32226.1 - 1.5e-20 73.1 6.0 0.0001 23.0 0.0 7.8 7 1 0 7 7 7 4 WD domain, G-beta repeat APC_basic PF05956.11 PFH32226.1 - 1.5 8.2 5.7 0.89 8.9 0.0 2.2 2 0 0 2 2 2 0 APC basic domain TSP_3 PF02412.18 PFH32229.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Thrombospondin type 3 repeat Clathrin PF00637.20 PFH32230.1 - 4.1e-10 39.7 0.5 0.64 9.9 0.0 7.1 6 2 2 8 8 8 2 Region in Clathrin and VPS TPR_7 PF13176.6 PFH32230.1 - 3.1e-08 33.1 22.5 0.71 10.0 0.0 9.2 8 1 0 8 8 8 4 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 PFH32230.1 - 1.2e-07 32.0 0.0 0.019 15.3 0.0 5.2 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Sec16_C PF12931.7 PFH32230.1 - 4.9e-06 26.4 19.0 0.1 12.2 0.8 5.7 4 1 0 4 4 4 3 Sec23-binding domain of Sec16 WD40 PF00400.32 PFH32230.1 - 0.00022 22.0 2.0 6 7.9 0.1 4.9 4 0 0 4 4 4 1 WD domain, G-beta repeat TPR_1 PF00515.28 PFH32230.1 - 0.00031 20.4 20.2 1.3 9.0 0.1 9.1 9 2 1 10 10 9 1 Tetratricopeptide repeat Gmad1 PF10647.9 PFH32230.1 - 0.064 13.0 0.3 0.18 11.6 0.3 1.8 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain DUF410 PF04190.13 PFH32230.1 - 0.15 11.8 4.8 12 5.6 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF410) TPR_12 PF13424.6 PFH32230.1 - 0.48 10.7 52.2 0.63 10.4 0.2 11.2 9 3 2 11 11 10 0 Tetratricopeptide repeat TPR_11 PF13414.6 PFH32230.1 - 0.73 9.6 5.0 41 4.0 0.0 4.9 5 0 0 5 5 5 0 TPR repeat Coatomer_WDAD PF04053.14 PFH32230.1 - 1.8 7.5 3.6 13 4.6 0.1 2.8 3 0 0 3 3 3 0 Coatomer WD associated region TPR_8 PF13181.6 PFH32230.1 - 2.2 8.7 18.5 1.5 9.2 0.1 7.5 8 2 1 9 9 8 0 Tetratricopeptide repeat YfdX PF10938.8 PFH32230.1 - 3.2 7.7 8.8 0.11 12.4 0.6 2.8 3 0 0 3 3 3 0 YfdX protein Nic96 PF04097.14 PFH32230.1 - 8.8 4.6 9.3 1 7.7 1.1 3.0 2 1 1 3 3 3 0 Nup93/Nic96 DUF4719 PF15843.5 PFH32233.1 - 0.58 10.2 6.6 0.15 12.1 1.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4719) TMEM239 PF15841.5 PFH32233.1 - 4 7.3 7.3 0.87 9.5 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 239 family bMG10 PF17973.1 PFH32234.1 - 1.1e-07 32.1 0.0 3.6e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain DUF11 PF01345.18 PFH32234.1 - 0.0011 19.2 0.0 0.0076 16.5 0.0 2.4 1 0 0 1 1 1 1 Domain of unknown function DUF11 MG2 PF01835.19 PFH32234.1 - 0.091 13.2 0.0 1.4 9.4 0.0 3.1 3 0 0 3 3 3 0 MG2 domain DUF485 PF04341.12 PFH32236.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DUF2615 PF11027.8 PFH32236.1 - 2.6 8.2 0.0 2.6 8.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) LRR_6 PF13516.6 PFH32237.1 - 1.1e-10 40.7 9.4 0.34 11.1 0.0 9.5 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 PFH32237.1 - 0.00074 19.7 2.1 1.5e+02 3.6 0.1 6.4 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 PFH32237.1 - 0.0016 18.8 10.0 0.027 14.9 0.6 4.8 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH32237.1 - 0.35 10.7 10.5 0.24 11.2 0.5 4.7 5 1 0 5 5 5 0 Leucine rich repeat PseudoU_synth_1 PF01416.20 PFH32238.1 - 1.8e-20 73.4 0.0 3.7e-17 62.8 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase KCNQC3-Ank-G_bd PF11956.8 PFH32238.1 - 0.024 14.9 0.1 0.05 13.9 0.1 1.5 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 PAPA-1 PF04795.12 PFH32239.1 - 0.28 12.0 3.5 3.8 8.4 3.5 3.1 1 0 0 1 1 1 0 PAPA-1-like conserved region Transcrip_act PF04949.13 PFH32241.1 - 0.02 14.8 0.1 0.059 13.3 0.1 1.8 1 0 0 1 1 1 0 Transcriptional activator CCDC92 PF14916.6 PFH32241.1 - 0.048 13.4 0.4 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain of unknown function SNARE PF05739.19 PFH32241.1 - 0.57 10.2 8.5 0.2 11.7 0.3 3.3 3 0 0 3 3 3 0 SNARE domain Nop14 PF04147.12 PFH32242.1 - 0.3 9.3 8.8 0.41 8.8 8.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2052 PF09747.9 PFH32243.1 - 8.8e-18 65.2 37.5 6.8e-09 36.1 19.2 3.6 2 1 1 3 3 3 2 Coiled-coil domain containing protein (DUF2052) Nop14 PF04147.12 PFH32243.1 - 4.3 5.4 25.4 6.2 4.9 25.4 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 PFH32243.1 - 6.4 4.7 12.4 10 4.1 12.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 PFH32244.1 - 0.003 18.3 0.1 0.27 12.2 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat SGL PF08450.12 PFH32244.1 - 0.074 12.6 0.0 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Ribosomal_L16 PF00252.18 PFH32245.1 - 4e-19 68.9 0.0 5.8e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e EF-hand_7 PF13499.6 PFH32246.1 - 7.3e-20 71.2 2.2 8.1e-12 45.4 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PFH32246.1 - 4.3e-18 63.4 2.9 2.9e-06 26.4 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PFH32246.1 - 5.6e-18 63.3 2.1 2.9e-07 29.9 0.2 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 PFH32246.1 - 8.7e-11 41.5 1.7 1.9e-05 24.4 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 PFH32246.1 - 7.4e-07 28.4 6.4 0.00031 20.1 0.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 PFH32246.1 - 7.8e-05 22.9 0.1 0.0013 19.0 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain Caleosin PF05042.13 PFH32246.1 - 0.011 15.6 0.0 1.7 8.6 0.0 2.9 2 1 1 3 3 3 0 Caleosin related protein Dockerin_1 PF00404.18 PFH32246.1 - 0.028 14.6 0.0 0.077 13.2 0.0 1.8 1 0 0 1 1 1 0 Dockerin type I domain EFhand_Ca_insen PF08726.10 PFH32246.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DNAPolymera_Pol PF11590.8 PFH32246.1 - 0.9 9.5 4.9 0.24 11.3 0.9 2.2 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol AP-5_subunit_s1 PF15001.6 PFH32248.1 - 1.1e-25 90.8 0.1 2.3e-22 79.9 0.0 2.1 2 0 0 2 2 2 2 AP-5 complex subunit sigma-1 Nuc_H_symport PF03825.16 PFH32248.1 - 0.038 13.0 0.9 0.048 12.6 0.9 1.1 1 0 0 1 1 1 0 Nucleoside H+ symporter Nop14 PF04147.12 PFH32249.1 - 0.013 13.8 14.3 0.019 13.2 14.3 1.1 1 0 0 1 1 1 0 Nop14-like family Pribosyltran_N PF13793.6 PFH32250.1 - 5.3e-48 161.8 0.1 6.7e-47 158.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 PFH32250.1 - 1.3e-32 113.3 0.3 2.7e-32 112.3 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 PFH32250.1 - 2e-14 53.4 0.1 4.5e-14 52.3 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 PFH32250.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DIX PF00778.17 PFH32251.1 - 2.9e-11 43.1 0.1 3.5e-10 39.6 0.1 2.0 1 1 0 1 1 1 1 DIX domain Metallophos PF00149.28 PFH32253.1 - 2.6e-34 119.5 0.4 3.9e-34 119.0 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PFH32253.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Thiolase_N PF00108.23 PFH32254.1 - 5.5e-81 271.7 0.6 7.1e-81 271.4 0.6 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PFH32254.1 - 2e-38 130.8 0.5 2e-38 130.8 0.5 2.2 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 PFH32254.1 - 0.17 11.5 3.1 0.13 11.8 0.9 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 PFH32254.1 - 0.28 11.1 0.1 0.28 11.1 0.1 3.4 3 1 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF4536 PF15055.6 PFH32255.1 - 0.00045 20.4 1.7 0.35 11.2 0.3 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4536) CD20 PF04103.15 PFH32255.1 - 0.0047 17.0 1.2 0.0077 16.3 1.2 1.4 1 0 0 1 1 1 1 CD20-like family Phage_holin_3_6 PF07332.11 PFH32255.1 - 0.012 15.6 0.2 0.018 15.1 0.2 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Saf_2TM PF18303.1 PFH32255.1 - 0.045 13.4 0.2 0.058 13.0 0.2 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF2207 PF09972.9 PFH32255.1 - 0.21 10.3 0.5 0.26 10.0 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4064 PF13273.6 PFH32255.1 - 0.25 11.6 2.1 0.76 10.1 2.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Borrelia_P83 PF05262.11 PFH32256.1 - 1.3 7.4 28.3 1.9 6.9 28.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PNTB PF02233.16 PFH32257.1 - 4.1e-169 563.3 23.5 1.7e-168 561.3 14.9 2.2 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 PFH32257.1 - 2.7e-63 213.1 0.0 5.8e-63 212.0 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PNTB_4TM PF12769.7 PFH32257.1 - 2.8e-32 111.0 1.3 2.8e-32 111.0 1.3 3.7 3 0 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch AlaDh_PNT_N PF05222.15 PFH32257.1 - 5.6e-21 75.3 0.1 7.5e-17 61.9 0.0 2.9 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, N-terminal domain Pyr_redox_2 PF07992.14 PFH32257.1 - 0.023 13.9 1.4 0.051 12.8 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 PFH32257.1 - 0.058 12.8 0.0 13 5.1 0.1 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3123 PF11321.8 PFH32257.1 - 0.067 13.9 1.9 5.5 7.7 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) DUF2678 PF10856.8 PFH32257.1 - 0.17 11.8 2.7 0.5 10.3 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) Pyr_redox PF00070.27 PFH32257.1 - 0.19 12.3 0.5 0.54 10.8 0.5 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Exo_endo_phos PF03372.23 PFH32258.1 - 2.3e-16 60.0 0.1 3.4e-15 56.2 0.1 2.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BHD_3 PF10405.9 PFH32259.1 - 1.4e-14 54.2 0.0 2.5e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 PFH32259.1 - 8.6e-11 41.5 0.0 1.4e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.15 PFH32259.1 - 2.6e-06 27.2 0.0 2e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 PFH32259.1 - 5.1e-06 27.3 2.0 5.1e-06 27.3 2.0 3.7 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 PFH32259.1 - 0.00013 22.4 0.2 0.0004 20.8 0.2 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_core2 PF13369.6 PFH32259.1 - 0.039 13.5 0.2 0.09 12.3 0.2 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily ATG16 PF08614.11 PFH32260.1 - 0.0044 17.3 2.5 0.0091 16.2 2.5 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF5526 PF17664.1 PFH32260.1 - 2 8.0 5.3 3.6 7.1 1.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5526) MPS2 PF17060.5 PFH32260.1 - 2.1 7.6 4.5 0.37 10.0 0.5 1.6 2 0 0 2 2 2 0 Monopolar spindle protein 2 Bestrophin PF01062.21 PFH32262.1 - 0.19 11.1 0.8 0.31 10.4 0.8 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Atg14 PF10186.9 PFH32262.1 - 0.25 10.4 3.5 0.61 9.1 3.5 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cluap1 PF10234.9 PFH32262.1 - 0.42 10.0 6.7 0.73 9.2 6.7 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF641 PF04859.12 PFH32262.1 - 0.55 10.6 5.6 2.8 8.3 1.6 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Cnn_1N PF07989.11 PFH32262.1 - 0.57 10.4 4.4 2.3 8.4 4.4 2.1 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 CCDC144C PF14915.6 PFH32262.1 - 0.95 8.5 8.9 0.078 12.1 1.3 2.0 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region MPS2 PF17060.5 PFH32262.1 - 1.5 8.0 3.2 2.4 7.3 3.2 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Csm1_N PF18504.1 PFH32262.1 - 2.2 8.7 5.3 3 8.2 2.0 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 PFH32262.1 - 2.7 8.1 6.5 7.5 6.6 6.4 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 PFH32262.1 - 3 6.6 6.8 4.7 6.0 6.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Pkinase PF00069.25 PFH32263.1 - 2.1e-29 102.7 0.0 3.3e-28 98.8 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32263.1 - 1.4e-21 77.0 0.0 1e-19 70.9 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase EDR1 PF14381.6 PFH32263.1 - 7.5e-11 42.1 0.0 1.4e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 LRR_6 PF13516.6 PFH32263.1 - 0.00041 20.2 8.6 0.33 11.1 0.3 6.4 7 0 0 7 7 7 1 Leucine Rich repeat APH PF01636.23 PFH32263.1 - 0.00042 20.3 0.0 0.0035 17.3 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family LRR_4 PF12799.7 PFH32263.1 - 0.012 16.0 5.9 8.1 7.0 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PFH32263.1 - 7.4 7.6 9.2 2.7e+02 2.8 0.1 6.0 7 0 0 7 7 7 0 Leucine Rich Repeat RNA_GG_bind PF10258.9 PFH32264.1 - 1.3e-22 79.6 0.0 3.7e-22 78.2 0.0 1.8 1 0 0 1 1 1 1 PHAX RNA-binding domain Phage_GP20 PF06810.11 PFH32265.1 - 0.0028 17.5 0.1 0.0045 16.8 0.1 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 DnaJ PF00226.31 PFH32266.1 - 1.1e-22 79.9 0.3 3e-22 78.5 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 PFH32266.1 - 2.5e-08 34.0 7.3 1.6e-07 31.4 2.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PFH32266.1 - 1.5e-07 31.5 6.8 3e-07 30.6 2.5 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 PFH32266.1 - 1.2e-06 28.8 2.5 0.055 14.3 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 PFH32266.1 - 1.9e-06 28.0 6.3 0.0034 17.8 1.5 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 PFH32266.1 - 1.3e-05 25.5 5.9 0.035 14.4 0.1 2.8 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 PFH32266.1 - 0.066 13.7 0.7 1.1 9.8 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 PFH32266.1 - 0.082 12.9 5.0 4.2 7.5 1.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4736 PF15883.5 PFH32266.1 - 0.11 12.2 4.9 0.22 11.2 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) zf-DBF PF07535.12 PFH32266.1 - 0.32 11.1 6.0 0.37 11.0 2.3 2.5 2 0 0 2 2 2 0 DBF zinc finger HBM PF16591.5 PFH32267.1 - 0.013 14.9 0.1 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 Helical bimodular sensor domain Planc_extracel PF07595.12 PFH32267.1 - 0.18 11.7 0.0 0.18 11.7 0.0 3.5 3 0 0 3 3 3 0 Planctomycete extracellular MCM6_C PF18263.1 PFH32267.1 - 0.42 10.9 4.1 1.8 8.9 0.4 2.7 3 0 0 3 3 3 0 MCM6 C-terminal winged-helix domain MCM6_C PF18263.1 PFH32268.1 - 0.19 11.9 1.8 3.6 7.9 0.3 2.6 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain SNARE_assoc PF09335.11 PFH32269.1 - 2.1e-15 57.3 10.0 2.1e-15 57.3 10.0 2.9 3 0 0 3 3 3 1 SNARE associated Golgi protein DHHC PF01529.20 PFH32270.1 - 7.8e-28 97.3 7.1 7.8e-28 97.3 7.1 3.7 4 1 0 4 4 4 1 DHHC palmitoyltransferase PHM7_cyt PF14703.6 PFH32270.1 - 5.4e-09 36.5 0.2 1e-08 35.6 0.2 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter GTP_EFTU PF00009.27 PFH32271.1 - 1.3e-51 174.9 0.1 2.1e-51 174.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 PFH32271.1 - 3.1e-17 62.4 0.4 7.9e-17 61.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 PFH32271.1 - 1.4e-06 28.3 0.1 2.8e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 PFH32271.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 PFH32271.1 - 0.086 12.9 0.0 0.84 9.7 0.0 2.1 1 1 1 2 2 2 0 Dynamin family BOP1NT PF08145.12 PFH32272.1 - 4.3e-94 315.3 0.7 9.5e-94 314.1 0.7 1.6 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 PFH32272.1 - 3.9e-13 49.7 5.4 0.096 13.6 0.1 7.1 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH32272.1 - 1e-06 29.0 0.0 1.3 9.4 0.0 5.7 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain ENTH PF01417.20 PFH32274.1 - 1.7e-06 28.1 0.0 2.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain SAS-6_N PF16531.5 PFH32275.1 - 1.7e-28 99.1 3.0 2.7e-28 98.4 3.0 1.3 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Maf PF02545.14 PFH32276.1 - 2.8e-32 111.9 0.0 2.2e-28 99.2 0.0 2.1 2 0 0 2 2 2 2 Maf-like protein X PF00739.19 PFH32276.1 - 8.4 6.5 10.5 28 4.8 10.3 1.9 2 0 0 2 2 2 0 Trans-activation protein X Pkinase PF00069.25 PFH32277.1 - 4.2e-79 265.6 0.3 6.2e-79 265.1 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32277.1 - 1.3e-41 142.6 0.0 1.9e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 PFH32277.1 - 3.4e-28 95.0 6.2 1.3e-06 27.5 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PFH32277.1 - 3.7e-24 85.0 8.9 3.2e-11 43.5 0.6 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PFH32277.1 - 2e-23 80.7 4.1 8.2e-06 25.1 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PFH32277.1 - 6.9e-23 78.6 3.6 6.8e-05 22.5 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PFH32277.1 - 1e-11 44.5 8.4 0.0037 17.1 0.2 4.1 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PFH32277.1 - 7.4e-07 29.5 1.6 0.086 13.2 0.1 3.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Pkinase_fungal PF17667.1 PFH32277.1 - 7.8e-07 28.2 0.0 1.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PFH32277.1 - 1.3e-06 27.9 0.3 0.007 15.7 0.0 2.9 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 PFH32277.1 - 7.5e-06 25.4 0.2 3.1e-05 23.4 0.2 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.7 PFH32277.1 - 4.1e-05 23.5 7.0 0.01 15.8 0.4 3.9 2 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand APH PF01636.23 PFH32277.1 - 0.0061 16.5 0.0 0.014 15.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_10 PF14788.6 PFH32277.1 - 0.018 14.9 0.2 0.47 10.4 0.0 3.1 3 0 0 3 3 3 0 EF hand MelC1 PF06236.11 PFH32277.1 - 0.05 13.7 0.2 0.1 12.7 0.2 1.4 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 YrbL-PhoP_reg PF10707.9 PFH32277.1 - 0.053 13.0 0.9 0.093 12.2 0.1 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Acetyltransf_18 PF18014.1 PFH32277.1 - 0.11 12.3 0.1 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain EF-hand_9 PF14658.6 PFH32277.1 - 0.21 12.0 1.3 1.6 9.1 0.0 3.0 3 1 0 3 3 3 0 EF-hand domain HP0268 PF18618.1 PFH32277.1 - 1.3 9.5 6.2 4.2 7.9 0.2 3.5 4 0 0 4 4 4 0 HP0268 VCBS PF13517.6 PFH32278.1 - 6.6e-19 68.3 21.3 6.7e-05 23.4 0.7 8.3 8 2 2 10 10 10 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PFH32278.1 - 8e-11 41.9 12.8 0.057 13.6 0.0 7.7 7 0 0 7 7 7 5 FG-GAP repeat PDGF PF00341.17 PFH32278.1 - 0.18 12.2 0.9 0.35 11.2 0.9 1.4 1 0 0 1 1 1 0 PDGF/VEGF domain DUF4573 PF15140.6 PFH32280.1 - 1.6e-06 28.1 14.9 2.4e-06 27.5 14.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) ISP3_C PF18045.1 PFH32282.1 - 3.4e-33 113.8 0.1 4.5e-33 113.4 0.1 1.1 1 0 0 1 1 1 1 ISP3 C-terminal ISP1_C PF18161.1 PFH32282.1 - 1.2e-27 96.0 0.2 1.4e-27 95.7 0.2 1.1 1 0 0 1 1 1 1 ISP1 C-terminal DNA_pol_A PF00476.20 PFH32283.1 - 2.1e-83 280.5 0.0 8.1e-70 235.8 0.0 2.1 2 0 0 2 2 2 2 DNA polymerase family A DNA_pol_P_Exo PF18049.1 PFH32283.1 - 0.17 11.3 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase nu pseudo-exo Methyltransf_32 PF13679.6 PFH32284.1 - 0.18 11.7 0.4 0.75 9.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.25 PFH32285.1 - 1.3e-48 165.7 0.0 3.8e-21 75.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32285.1 - 3.3e-27 95.4 0.0 6.2e-15 55.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.32 PFH32285.1 - 1.1e-09 37.1 3.4 0.0005 19.4 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PFH32285.1 - 6.5e-09 35.0 4.2 0.0023 17.7 0.6 2.8 3 0 0 3 3 3 2 EF-hand domain PH PF00169.29 PFH32285.1 - 6e-07 29.9 0.0 1.4e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 PH domain EF-hand_7 PF13499.6 PFH32285.1 - 9.6e-06 26.0 2.8 3.7e-05 24.1 2.5 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PFH32285.1 - 0.0063 16.0 3.5 0.011 15.2 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 PFH32285.1 - 0.01 15.7 6.1 0.3 11.0 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair CCDC24 PF15669.5 PFH32285.1 - 4 7.3 0.0 4 7.3 0.0 6.0 5 1 0 6 6 6 0 Coiled-coil domain-containing protein 24 family FYVE PF01363.21 PFH32286.1 - 2.8e-16 59.4 8.0 2.8e-16 59.4 8.0 1.9 2 0 0 2 2 2 1 FYVE zinc finger Sds3 PF08598.11 PFH32286.1 - 0.00041 20.4 0.2 0.00057 19.9 0.2 1.2 1 0 0 1 1 1 1 Sds3-like CENP-K PF11802.8 PFH32286.1 - 0.34 10.4 5.8 0.53 9.8 5.8 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Exonuc_VII_L PF02601.15 PFH32286.1 - 0.41 10.2 6.8 0.67 9.5 6.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.22 PFH32286.1 - 0.56 10.5 10.4 1.4 9.2 10.3 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.11 PFH32286.1 - 0.82 9.5 6.6 0.61 9.9 3.5 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 Spc7 PF08317.11 PFH32286.1 - 9.5 5.0 14.8 56 2.5 14.7 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein Pkinase PF00069.25 PFH32288.1 - 7.3e-63 212.4 0.0 2.5e-50 171.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32288.1 - 3.6e-26 92.0 0.1 1.2e-18 67.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.32 PFH32288.1 - 1e-15 56.0 3.8 0.0002 20.7 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PFH32288.1 - 1.5e-14 54.2 3.9 1.1e-06 29.0 0.5 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH32288.1 - 3.4e-12 45.2 4.0 0.00089 19.0 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 PFH32288.1 - 9e-07 28.1 0.7 0.038 13.5 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PFH32288.1 - 1.8e-06 27.7 2.6 0.33 10.8 0.0 4.2 2 1 2 4 4 4 2 EF-hand domain pair Kdo PF06293.14 PFH32288.1 - 0.0009 18.6 0.1 0.0019 17.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH32288.1 - 0.0054 16.7 0.3 0.024 14.5 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family EF-hand_9 PF14658.6 PFH32288.1 - 0.095 13.0 0.1 23 5.4 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain Choline_kinase PF01633.20 PFH32288.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ECH_1 PF00378.20 PFH32289.1 - 1.2e-75 254.1 0.0 1.4e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PFH32289.1 - 1.3e-41 143.2 0.7 2.2e-38 132.6 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 PFH32289.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DUF3052 PF11253.8 PFH32289.1 - 0.13 12.2 0.1 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3052) eIF-3_zeta PF05091.12 PFH32290.1 - 3.6e-150 501.4 0.0 4.6e-150 501.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ribosomal_S6e PF01092.19 PFH32291.1 - 2.3e-53 179.4 0.1 2.3e-53 179.4 0.1 1.8 2 1 0 2 2 2 1 Ribosomal protein S6e Atg14 PF10186.9 PFH32291.1 - 1.7 7.6 10.9 2.4 7.1 10.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 VPS13_C PF16909.5 PFH32292.1 - 1.9e-26 93.0 0.1 4e-22 78.8 0.0 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 PFH32292.1 - 1.8e-08 34.5 0.0 0.00029 20.7 0.0 4.3 4 1 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 PFH32292.1 - 5.2e-06 26.6 0.0 2.5e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 PFH32292.1 - 5.4e-06 26.7 0.0 2.5e-05 24.6 0.0 2.2 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain AAA_2 PF07724.14 PFH32293.1 - 5.1e-27 95.1 1.9 6.9e-20 71.8 0.1 3.3 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 PFH32293.1 - 2.3e-17 63.7 0.7 1.1e-07 32.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PFH32293.1 - 5.1e-08 33.0 0.1 5.3e-06 26.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PFH32293.1 - 1.4e-06 28.8 0.5 9e-06 26.2 0.1 2.5 3 0 0 3 3 3 1 AAA ATPase domain ClpB_D2-small PF10431.9 PFH32293.1 - 2.4e-06 27.5 0.2 8.3e-06 25.8 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 PFH32293.1 - 6e-06 25.5 0.0 0.0035 16.5 0.0 2.4 2 0 0 2 2 2 2 MCM P-loop domain AAA_22 PF13401.6 PFH32293.1 - 1.6e-05 25.2 0.1 0.00098 19.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 PFH32293.1 - 0.00031 20.7 0.0 0.28 11.1 0.0 2.7 2 0 0 2 2 2 2 NACHT domain Rad17 PF03215.15 PFH32293.1 - 0.0011 18.9 0.0 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain Mg_chelatase PF01078.21 PFH32293.1 - 0.0015 17.9 0.0 0.008 15.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 PFH32293.1 - 0.0031 17.8 3.5 0.0033 17.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 PFH32293.1 - 0.0045 17.2 0.0 0.016 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PFH32293.1 - 0.0075 16.0 0.0 0.043 13.6 0.0 2.3 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 PFH32293.1 - 0.011 16.3 0.0 0.034 14.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PFH32293.1 - 0.032 14.2 0.0 8.7 6.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 PFH32293.1 - 0.034 13.9 0.0 0.086 12.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 PFH32293.1 - 0.079 12.9 0.1 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 PFH32293.1 - 0.086 12.4 0.1 7.3 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 PFH32293.1 - 0.089 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 PFH32293.1 - 0.092 13.1 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 PFH32293.1 - 0.093 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 PFH32293.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 PFH32293.1 - 0.13 12.7 0.1 0.58 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 PFH32293.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 PFH32293.1 - 0.17 12.3 3.0 0.27 11.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain tRNA-synt_2d PF01409.20 PFH32294.1 - 4.3e-31 108.2 0.0 4.3e-18 65.7 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 PFH32294.1 - 2.7e-19 69.4 0.0 1.3e-15 57.6 0.0 2.5 2 0 0 2 2 2 2 Ferredoxin-fold anticodon binding domain Peptidase_C26 PF07722.13 PFH32295.1 - 1.2e-29 103.6 0.1 3.6e-17 62.8 0.0 4.0 3 1 0 3 3 3 3 Peptidase C26 GATase PF00117.28 PFH32295.1 - 6.3e-06 26.1 2.2 0.00089 19.1 1.0 2.5 2 1 0 2 2 2 2 Glutamine amidotransferase class-I CENP-H PF05837.12 PFH32296.1 - 6.3 7.3 13.0 0.2 12.1 5.0 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) YccV-like PF08755.11 PFH32297.1 - 2.8e-22 79.0 0.0 5e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like PRKCSH PF07915.13 PFH32297.1 - 1.6e-16 61.1 2.1 3.4e-07 31.2 0.1 3.1 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 PFH32297.1 - 0.0049 16.6 0.0 0.51 10.0 0.0 2.8 2 1 1 3 3 3 1 Glucosidase II beta subunit-like protein UCH PF00443.29 PFH32298.1 - 1.3e-34 119.9 0.0 2e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PFH32298.1 - 5.6e-06 26.2 0.0 0.00024 20.8 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Evr1_Alr PF04777.13 PFH32299.1 - 2.5e-19 69.6 0.0 3.4e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family DHO_dh PF01180.21 PFH32300.1 - 2.9e-98 328.7 0.0 3.6e-98 328.4 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 PFH32300.1 - 0.021 14.2 0.1 0.037 13.4 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase FMN_dh PF01070.18 PFH32300.1 - 0.052 12.6 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Aha1_N PF09229.11 PFH32301.1 - 2.8e-47 160.4 0.4 3.4e-24 85.6 0.0 2.3 2 0 0 2 2 2 2 Activator of Hsp90 ATPase, N-terminal Autotransporter PF03797.19 PFH32301.1 - 0.04 13.6 0.1 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Autotransporter beta-domain V_ATPase_I PF01496.19 PFH32301.1 - 0.13 10.1 3.2 0.16 9.9 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Radial_spoke_3 PF06098.11 PFH32301.1 - 0.92 8.7 11.6 1.5 8.1 11.6 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 Nucleoside_tran PF01733.18 PFH32303.1 - 4.1e-06 26.4 6.3 0.081 12.3 0.0 3.2 3 0 0 3 3 3 3 Nucleoside transporter RIO1 PF01163.22 PFH32304.1 - 6.1e-50 169.4 0.0 1.9e-25 89.6 0.0 2.5 2 0 0 2 2 2 2 RIO1 family tRNA-synt_1d PF00750.19 PFH32305.1 - 2.3e-119 398.4 0.5 8.5e-111 370.2 0.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 PFH32305.1 - 1e-31 109.5 0.0 3.3e-31 107.9 0.0 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 PFH32305.1 - 6.9e-16 58.6 0.1 2.1e-15 57.0 0.1 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 PFH32305.1 - 0.0034 16.8 0.0 0.0095 15.3 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain SBP_bac_5 PF00496.22 PFH32305.1 - 0.0079 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle FOG_N PF15888.5 PFH32306.1 - 0.02 15.3 0.8 0.02 15.3 0.8 12.3 5 3 10 15 15 15 0 Folded gastrulation N-terminus SH3_5 PF08460.10 PFH32306.1 - 0.03 14.4 7.7 41 4.4 0.0 6.9 6 2 1 8 8 8 0 Bacterial SH3 domain AAA PF00004.29 PFH32307.1 - 6.5e-14 52.5 0.0 1.2e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 PFH32307.1 - 9.4e-14 51.5 0.1 1.5e-11 44.4 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 PFH32307.1 - 6.8e-13 48.8 0.0 1.9e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_16 PF13191.6 PFH32307.1 - 7.4e-07 29.7 0.1 0.00056 20.3 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 PFH32307.1 - 7.6e-07 29.0 0.1 6.9e-06 25.9 0.1 2.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 PFH32307.1 - 2.5e-06 27.6 0.0 4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 PFH32307.1 - 1.4e-05 24.6 0.0 0.00043 19.7 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 PFH32307.1 - 2.3e-05 24.0 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 PFH32307.1 - 3.2e-05 24.2 0.6 0.06 13.6 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 PFH32307.1 - 3.8e-05 23.7 0.1 0.00013 22.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 PFH32307.1 - 3.8e-05 22.9 0.0 8.3e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain AAA_11 PF13086.6 PFH32307.1 - 7.8e-05 22.6 0.1 0.0001 22.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PFH32307.1 - 9.9e-05 22.7 0.2 0.0056 17.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 PFH32307.1 - 0.00012 21.9 0.0 0.00034 20.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 PFH32307.1 - 0.00013 21.9 0.0 0.0012 18.8 0.0 2.2 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 PFH32307.1 - 0.00023 21.5 0.0 0.00062 20.1 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 PFH32307.1 - 0.00089 19.1 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DEAD PF00270.29 PFH32307.1 - 0.0035 17.1 0.2 0.16 11.7 0.1 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_24 PF13479.6 PFH32307.1 - 0.0054 16.5 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 PFH32307.1 - 0.0061 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 PFH32307.1 - 0.0089 16.0 0.0 3 7.8 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TniB PF05621.11 PFH32307.1 - 0.012 15.0 0.5 0.65 9.4 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 PFH32307.1 - 0.015 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PFH32307.1 - 0.017 14.8 0.0 0.077 12.7 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 PFH32307.1 - 0.031 14.8 0.0 0.075 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 PFH32307.1 - 0.042 13.0 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 PFH32307.1 - 0.047 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.6 PFH32307.1 - 0.056 13.0 1.5 0.39 10.3 0.3 2.5 1 1 2 3 3 3 0 AAA domain NTPase_1 PF03266.15 PFH32307.1 - 0.062 13.2 0.8 4.2 7.2 0.0 2.8 1 1 1 2 2 2 0 NTPase LEM PF03020.15 PFH32307.1 - 0.1 12.2 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 LEM domain Sigma54_activat PF00158.26 PFH32307.1 - 0.14 11.9 0.0 9.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain LUC7 PF03194.15 PFH32308.1 - 1.5e-62 211.6 7.6 1.5e-62 211.6 7.6 1.8 2 0 0 2 2 2 1 LUC7 N_terminus DUF4404 PF14357.6 PFH32308.1 - 0.026 15.1 2.0 0.083 13.5 2.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) GIT_CC PF16559.5 PFH32308.1 - 1.5 8.7 3.8 1.1 9.2 0.1 2.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Myb_DNA-binding PF00249.31 PFH32310.1 - 0.00084 19.5 0.0 0.41 10.9 0.1 3.0 2 1 0 2 2 2 2 Myb-like DNA-binding domain RRM_1 PF00076.22 PFH32311.1 - 6.9e-16 57.8 0.0 1.1e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PFH32311.1 - 0.0097 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3138 PF11336.8 PFH32311.1 - 0.026 13.2 2.3 0.041 12.5 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RRM_7 PF16367.5 PFH32311.1 - 0.19 11.9 0.0 0.57 10.3 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif FMN_bind PF04205.14 PFH32312.1 - 0.14 12.7 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 FMN-binding domain Sec61_beta PF03911.16 PFH32313.1 - 1.9e-18 66.2 0.0 1.9e-18 66.2 0.0 1.4 2 0 0 2 2 2 1 Sec61beta family AAA PF00004.29 PFH32314.1 - 1.6e-13 51.2 0.0 4.5e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.27 PFH32314.1 - 4.3e-05 22.9 2.7 0.00013 21.4 2.7 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_22 PF13401.6 PFH32314.1 - 0.00049 20.4 0.1 0.033 14.5 0.0 3.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 PFH32314.1 - 0.00052 19.8 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PFH32314.1 - 0.00056 20.3 1.1 0.006 17.0 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_24 PF13479.6 PFH32314.1 - 0.0056 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 PFH32314.1 - 0.0091 15.9 0.1 2.7 7.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 PFH32314.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PFH32314.1 - 0.085 12.9 0.1 0.33 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 PFH32314.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 PFH32314.1 - 0.17 12.4 0.0 0.63 10.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter HeLo PF14479.6 PFH32314.1 - 1.2 8.9 8.4 0.035 13.9 1.8 1.8 2 0 0 2 2 2 0 Prion-inhibition and propagation Aminotran_5 PF00266.19 PFH32316.1 - 8.8e-77 258.6 0.0 7.3e-76 255.5 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PFH32316.1 - 1.7e-05 24.2 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 PFH32316.1 - 0.00012 21.5 0.0 0.00029 20.3 0.0 1.6 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 PFH32316.1 - 0.00021 20.1 0.0 0.00035 19.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 PFH32316.1 - 0.0074 15.5 0.0 0.37 9.9 0.0 2.2 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 PFH32316.1 - 0.085 11.4 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme VPS13 PF16908.5 PFH32317.1 - 5e-09 36.3 1.7 0.0019 18.0 0.0 3.8 2 2 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal EST1_DNA_bind PF10373.9 PFH32317.1 - 9.1 5.7 8.6 5 6.5 0.1 2.9 2 1 1 3 3 3 0 Est1 DNA/RNA binding domain AAA_16 PF13191.6 PFH32318.1 - 2.8e-07 31.1 1.3 2.8e-07 31.1 1.3 2.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PFH32318.1 - 0.0005 20.4 0.1 0.0042 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain ORC4_C PF14629.6 PFH32318.1 - 0.0012 18.3 0.7 0.029 13.7 0.7 2.4 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus NACHT PF05729.12 PFH32318.1 - 0.013 15.4 0.1 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 PFH32318.1 - 0.016 15.7 0.0 0.39 11.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 PFH32318.1 - 0.025 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 PFH32318.1 - 0.036 14.4 0.0 0.079 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 PFH32318.1 - 0.054 13.4 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TEX19 PF15553.6 PFH32318.1 - 0.088 12.8 0.1 0.29 11.1 0.1 1.8 1 0 0 1 1 1 0 Testis-expressed protein 19 T2SSE PF00437.20 PFH32318.1 - 0.096 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 PFH32318.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 PFH32318.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 PFH32318.1 - 0.21 11.1 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region IF-2B PF01008.17 PFH32319.1 - 9.6e-41 139.8 0.4 1.8e-40 138.9 0.4 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family PTH2 PF01981.16 PFH32320.1 - 3.6e-45 153.0 0.0 4e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 ABC_transp_aux PF09822.9 PFH32320.1 - 0.22 10.9 0.0 0.26 10.7 0.0 1.1 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Pkinase PF00069.25 PFH32322.1 - 0.001 18.5 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Big_5 PF13205.6 PFH32323.1 - 7e-10 39.6 0.0 0.00064 20.4 0.0 4.7 4 0 0 4 4 4 2 Bacterial Ig-like domain Notch PF00066.17 PFH32323.1 - 2.6e-06 27.8 11.6 2.9e-05 24.4 11.6 3.0 1 0 0 1 1 1 1 LNR domain DUF2627 PF11118.8 PFH32323.1 - 0.21 12.2 0.0 0.4 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) APG6_N PF17675.1 PFH32324.1 - 0.011 16.3 2.4 0.038 14.5 2.4 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region YbjQ_1 PF01906.17 PFH32326.1 - 3.4e-26 91.9 2.4 8.4e-26 90.6 2.4 1.7 1 0 0 1 1 1 1 Putative heavy-metal-binding DUF4156 PF13698.6 PFH32326.1 - 0.00057 20.2 0.1 0.0012 19.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4156) RCC1 PF00415.18 PFH32327.1 - 3.6e-10 40.3 19.0 7.9e-05 23.2 0.1 7.7 9 0 0 9 9 9 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH32327.1 - 2.6e-08 33.4 11.3 0.00021 21.0 0.4 5.2 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat I_LWEQ PF01608.17 PFH32327.1 - 1.5 9.0 5.0 14 5.9 3.3 2.6 2 0 0 2 2 2 0 I/LWEQ domain DUF438 PF04282.13 PFH32328.1 - 0.18 11.8 0.3 0.89 9.5 0.2 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF438) LRR_4 PF12799.7 PFH32328.1 - 0.94 10.0 5.6 14 6.2 0.0 3.8 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Peptidase_M24 PF00557.24 PFH32329.1 - 1.7e-46 158.5 0.0 2.3e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 ATG13 PF10033.9 PFH32330.1 - 0.048 13.4 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Autophagy-related protein 13 DUF21 PF01595.20 PFH32331.1 - 8e-34 116.9 0.1 1.2e-33 116.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 PFH32331.1 - 5e-07 30.1 1.8 0.00046 20.6 0.0 3.0 3 0 0 3 3 3 2 CBS domain PBAN PF05874.11 PFH32332.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) WD40_3 PF15911.5 PFH32333.1 - 3.1e-17 62.3 0.0 7.6e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH32333.1 - 2.4e-12 47.0 0.7 0.012 15.9 0.0 5.1 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 PFH32333.1 - 4.8e-10 39.5 9.8 0.0047 16.8 0.2 5.4 3 2 2 5 5 5 3 Region in Clathrin and VPS TPR_14 PF13428.6 PFH32333.1 - 1.4e-06 28.6 42.3 0.043 14.6 0.9 10.5 9 1 1 10 10 10 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 PFH32333.1 - 2.8e-06 26.7 4.1 0.042 12.9 0.2 4.8 3 1 2 5 5 5 1 Coatomer WD associated region TPR_2 PF07719.17 PFH32333.1 - 0.00043 20.2 35.4 0.022 14.9 1.0 9.3 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 PFH32333.1 - 0.0011 18.8 17.5 1.2 9.3 0.8 7.7 7 1 0 7 7 7 1 Tetratricopeptide repeat Nic96 PF04097.14 PFH32333.1 - 0.019 13.4 4.5 5.3 5.4 0.0 3.6 2 1 1 3 3 3 0 Nup93/Nic96 eIF2A PF08662.11 PFH32333.1 - 0.052 13.4 0.0 0.68 9.8 0.0 2.5 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DZR PF12773.7 PFH32333.1 - 0.086 12.9 2.0 0.23 11.5 2.0 1.7 1 0 0 1 1 1 0 Double zinc ribbon IKI3 PF04762.12 PFH32333.1 - 0.18 9.7 0.8 1.5 6.7 0.0 2.7 2 2 2 4 4 4 0 IKI3 family TPR_12 PF13424.6 PFH32333.1 - 0.69 10.2 31.9 0.13 12.6 1.8 8.1 6 2 1 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.9 PFH32333.1 - 2 8.1 7.1 42 3.8 0.0 4.6 6 0 0 6 6 6 0 26S proteasome subunit RPN7 TPR_19 PF14559.6 PFH32333.1 - 4.2 7.9 33.7 8.3 7.0 0.5 9.3 7 2 3 10 10 10 0 Tetratricopeptide repeat WD40 PF00400.32 PFH32333.1 - 8.9 7.4 5.9 20 6.3 0.1 4.2 5 0 0 5 5 3 0 WD domain, G-beta repeat ThiF PF00899.21 PFH32336.1 - 1e-08 34.9 0.0 2.1e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 ThiF family DEAD PF00270.29 PFH32337.1 - 1e-21 77.5 0.0 1.9e-12 47.3 0.0 3.1 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH32337.1 - 5.1e-19 68.7 0.0 6.7e-18 65.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH32337.1 - 6.3e-06 26.3 0.0 2.6e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PFH32337.1 - 0.013 15.8 0.0 0.037 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PFH32337.1 - 0.086 13.1 0.0 0.67 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Pre-PUA PF17832.1 PFH32338.1 - 2.9e-19 69.6 0.0 1.2e-18 67.5 0.0 2.2 2 0 0 2 2 2 1 Pre-PUA-like domain SUI1 PF01253.22 PFH32338.1 - 4.2e-14 52.8 0.0 1.1e-13 51.5 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.20 PFH32338.1 - 0.044 13.7 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 PUA domain RRM_1 PF00076.22 PFH32339.1 - 1e-17 63.7 0.0 1.4e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH32339.1 - 0.0001 22.3 0.0 0.0004 20.4 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 PFH32339.1 - 0.00048 19.7 0.0 0.00065 19.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PFH32339.1 - 0.078 12.8 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Occluded RNA-recognition motif LRR_9 PF14580.6 PFH32340.1 - 9.7e-19 67.5 1.9 3.9e-18 65.6 1.4 2.1 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 PFH32340.1 - 3.1e-15 56.0 23.7 2.3e-07 31.0 5.2 4.3 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH32340.1 - 4.5e-11 42.4 31.4 1.6e-06 27.8 1.9 4.0 3 1 2 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 PFH32340.1 - 0.26 11.5 11.4 17 5.8 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich repeat INTS5_N PF14837.6 PFH32340.1 - 0.46 10.1 2.7 0.31 10.6 0.2 1.9 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus DUF4358 PF14270.6 PFH32340.1 - 0.49 10.7 4.1 5.3 7.4 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) LRR_1 PF00560.33 PFH32340.1 - 2.8 8.8 15.9 32 5.6 0.1 5.6 4 1 0 4 4 4 0 Leucine Rich Repeat ZnuA PF01297.17 PFH32341.1 - 0.067 12.6 0.5 0.15 11.5 0.5 1.5 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic PseudoU_synth_1 PF01416.20 PFH32342.1 - 2.5e-11 44.0 0.0 7.9e-09 36.0 0.0 3.6 2 1 0 2 2 2 1 tRNA pseudouridine synthase LRS4 PF10422.9 PFH32343.1 - 0.028 14.0 0.4 0.052 13.1 0.4 1.4 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Fcf2 PF08698.11 PFH32344.1 - 2.4e-20 72.7 0.0 4.8e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing MMR_HSR1 PF01926.23 PFH32345.1 - 5.3e-45 152.2 0.0 3.7e-21 75.3 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 PFH32345.1 - 2.3e-23 82.3 0.1 4e-23 81.5 0.1 1.4 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 PFH32345.1 - 1e-17 64.3 0.0 1.1e-06 28.4 0.3 5.6 5 1 0 5 5 5 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 PFH32345.1 - 1e-16 60.9 0.0 2.9e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PFH32345.1 - 1.4e-06 28.3 0.0 0.085 12.8 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase Roc PF08477.13 PFH32345.1 - 4.3e-06 26.9 0.0 0.46 10.7 0.0 3.8 3 1 1 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 PFH32345.1 - 1.1e-05 24.8 0.0 0.013 14.8 0.0 2.3 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.23 PFH32345.1 - 5.7e-05 23.2 0.0 1.1 9.3 0.1 3.6 3 1 1 4 4 4 2 Dynamin family AAA_22 PF13401.6 PFH32345.1 - 0.00016 21.9 0.1 0.99 9.7 0.0 3.6 3 1 0 3 3 3 2 AAA domain cobW PF02492.19 PFH32345.1 - 0.0019 17.8 0.5 0.13 11.8 0.5 3.0 2 2 2 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 PFH32345.1 - 0.0028 17.3 0.0 0.54 9.9 0.0 3.1 2 1 0 2 2 2 1 Ras family AAA_18 PF13238.6 PFH32345.1 - 0.0043 17.6 0.0 0.48 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 PFH32345.1 - 0.0059 17.1 0.0 5.6 7.5 0.0 2.8 3 0 0 3 3 3 1 ABC transporter SRPRB PF09439.10 PFH32345.1 - 0.0072 15.8 0.0 10 5.5 0.0 3.1 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit MeaB PF03308.16 PFH32345.1 - 0.0073 15.3 0.0 8.9 5.2 0.1 3.9 4 0 0 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 PFH32345.1 - 0.013 15.2 0.0 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PFH32345.1 - 0.018 15.3 0.4 9.7 6.4 0.0 3.7 3 1 0 3 3 3 0 AAA domain MCM PF00493.23 PFH32345.1 - 0.021 14.0 0.0 0.22 10.6 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain TniB PF05621.11 PFH32345.1 - 0.042 13.3 0.0 4.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 PFH32345.1 - 0.19 12.1 0.0 10 6.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase zf-NF-X1 PF01422.17 PFH32350.1 - 0.9 9.7 4.7 2.6 8.2 4.7 1.8 1 0 0 1 1 1 0 NF-X1 type zinc finger DUF501 PF04417.12 PFH32351.1 - 6.9e-25 87.5 0.1 1.8e-16 60.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF501) S1 PF00575.23 PFH32352.1 - 1.1e-27 96.2 0.9 1e-12 48.2 0.0 2.4 2 0 0 2 2 2 2 S1 RNA binding domain zf-CCHC_3 PF13917.6 PFH32352.1 - 1.5e-11 44.0 0.5 3.6e-11 42.8 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle SR-25 PF10500.9 PFH32352.1 - 0.0018 17.9 34.4 0.0031 17.1 34.4 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SEEEED PF14797.6 PFH32352.1 - 0.0056 16.8 29.0 0.011 15.9 29.0 1.4 1 0 0 1 1 1 1 Serine-rich region of AP3B1, clathrin-adaptor complex CpXC PF14353.6 PFH32352.1 - 0.017 15.1 0.2 0.037 14.1 0.2 1.6 1 1 0 1 1 1 0 CpXC protein S1_2 PF13509.6 PFH32352.1 - 0.026 14.6 0.0 1.9 8.6 0.0 2.9 2 2 0 2 2 2 0 S1 domain CSD PF00313.22 PFH32352.1 - 0.074 12.9 0.5 7.5 6.5 0.0 2.5 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain zf-CCHC PF00098.23 PFH32352.1 - 0.15 12.2 5.1 0.29 11.3 5.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Zip PF02535.22 PFH32352.1 - 0.22 10.7 10.5 0.31 10.2 10.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF936 PF06075.12 PFH32352.1 - 0.31 9.9 18.4 0.37 9.6 18.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SAPS PF04499.15 PFH32352.1 - 0.34 9.6 5.8 0.45 9.2 5.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Rtf2 PF04641.12 PFH32352.1 - 0.36 10.1 21.5 0.52 9.6 21.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger TFIIF_alpha PF05793.12 PFH32352.1 - 0.54 8.8 26.3 0.88 8.1 26.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MRI PF15325.6 PFH32352.1 - 0.87 10.7 9.7 2.2 9.4 9.7 1.8 1 0 0 1 1 1 0 Modulator of retrovirus infection Macoilin PF09726.9 PFH32352.1 - 1.2 7.6 15.7 1.6 7.2 15.7 1.1 1 0 0 1 1 1 0 Macoilin family FAM60A PF15396.6 PFH32352.1 - 1.4 8.8 17.5 2.5 8.0 17.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Slu7 PF11708.8 PFH32352.1 - 1.5 8.5 21.9 2.4 7.8 21.9 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Nucleo_P87 PF07267.11 PFH32352.1 - 2.8 6.7 13.8 3.8 6.3 13.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CCDC106 PF15794.5 PFH32352.1 - 3.3 7.4 26.4 7.4 6.2 26.4 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 PFH32352.1 - 4.1 5.6 18.3 5.3 5.2 18.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 PFH32352.1 - 5.6 5.6 16.1 8.3 5.1 16.1 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 PFH32352.1 - 5.9 4.9 7.4 7.1 4.6 7.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Thioredoxin PF00085.20 PFH32353.1 - 4.6e-61 203.2 2.0 3.3e-31 107.3 0.1 3.5 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 PFH32353.1 - 5.9e-30 104.5 5.0 1e-17 64.7 0.8 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 PFH32353.1 - 4e-13 49.2 3.6 1.3e-12 47.5 3.5 1.8 1 1 0 1 1 1 1 Calsequestrin OST3_OST6 PF04756.13 PFH32353.1 - 2.9e-11 43.3 0.0 2.1e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PFH32353.1 - 6.3e-10 39.3 0.0 0.0099 16.2 0.0 4.0 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 PFH32353.1 - 1.6e-09 38.2 3.1 0.00036 20.9 0.1 4.2 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PFH32353.1 - 1.6e-08 34.6 0.1 0.0055 16.9 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 PFH32353.1 - 3.6e-08 33.4 0.3 0.00013 21.9 0.0 2.7 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 PFH32353.1 - 7.2e-08 32.3 1.5 0.0022 17.7 0.2 2.8 3 0 0 3 3 3 2 Redoxin TraF PF13728.6 PFH32353.1 - 3.8e-07 30.1 0.0 0.0047 16.8 0.0 2.6 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 PFH32353.1 - 0.0011 18.7 0.1 1.1 9.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 PFH32353.1 - 0.0044 17.2 3.0 2.7 8.3 0.0 4.4 4 1 0 4 4 4 1 Glutaredoxin HyaE PF07449.11 PFH32353.1 - 0.017 15.1 0.0 5.3 7.0 0.0 3.2 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE AAA_12 PF13087.6 PFH32354.1 - 1.6e-53 181.3 0.0 2.5e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PFH32354.1 - 1.2e-42 146.5 3.1 6.6e-25 88.4 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 PFH32354.1 - 9.4e-11 41.8 0.0 4.4e-10 39.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PFH32354.1 - 2.2e-09 37.8 0.0 1.3e-08 35.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 PFH32354.1 - 0.0004 20.4 0.0 0.00082 19.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PIF1 PF05970.14 PFH32354.1 - 0.00058 19.1 0.0 0.0049 16.1 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase ResIII PF04851.15 PFH32354.1 - 0.003 17.6 0.0 0.0086 16.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 PFH32354.1 - 0.0032 16.7 0.4 0.043 13.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) dsrm PF00035.26 PFH32354.1 - 0.0099 16.6 0.2 0.089 13.5 0.1 2.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif AAA_16 PF13191.6 PFH32354.1 - 0.011 16.1 0.4 0.19 12.1 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 PFH32354.1 - 0.015 15.7 0.1 0.07 13.6 0.0 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 PFH32354.1 - 0.015 15.0 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 PFH32354.1 - 0.036 13.5 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.29 PFH32354.1 - 0.062 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase SAC3_GANP PF03399.16 PFH32356.1 - 7.6e-32 110.9 0.0 7.6e-32 110.9 0.0 2.9 2 1 0 2 2 2 1 SAC3/GANP family DDHD PF02862.17 PFH32356.1 - 6.3 6.9 6.2 22 5.1 6.2 2.0 1 0 0 1 1 1 0 DDHD domain TB2_DP1_HVA22 PF03134.19 PFH32357.1 - 7.6e-11 41.8 5.9 7.6e-11 41.8 5.9 1.6 1 1 0 1 1 1 1 TB2/DP1, HVA22 family ABC2_membrane_3 PF12698.7 PFH32357.1 - 0.048 12.8 3.7 0.07 12.2 3.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein AP2 PF00847.20 PFH32358.1 - 8.2e-12 45.2 3.9 8.2e-12 45.2 3.9 2.0 2 0 0 2 2 2 1 AP2 domain SET PF00856.28 PFH32359.1 - 4.2e-15 56.5 4.5 8.7e-14 52.3 0.0 3.9 3 0 0 3 3 3 2 SET domain Radial_spoke_3 PF06098.11 PFH32361.1 - 5.1e-38 131.0 1.2 5.1e-38 131.0 1.2 2.5 2 1 0 2 2 2 1 Radial spoke protein 3 Pkinase PF00069.25 PFH32362.1 - 6.9e-16 58.4 0.0 4.1e-14 52.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 PFH32362.1 - 6.8e-07 28.9 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH32362.1 - 1e-05 25.0 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PFH32362.1 - 0.044 13.1 0.1 0.072 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PFH32362.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF108 PF01958.18 PFH32362.1 - 0.15 12.4 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF108 APH PF01636.23 PFH32362.1 - 0.7 9.8 5.4 1.2 9.0 3.2 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family S1-P1_nuclease PF02265.16 PFH32363.1 - 1.6e-16 60.9 0.1 2.5e-15 57.0 0.1 2.1 1 1 0 1 1 1 1 S1/P1 Nuclease SPRY PF00622.28 PFH32367.1 - 0.021 14.9 0.0 0.042 14.0 0.0 1.5 1 1 0 1 1 1 0 SPRY domain Macro PF01661.21 PFH32369.1 - 9.7e-31 106.3 0.1 1.9e-30 105.3 0.1 1.5 1 0 0 1 1 1 1 Macro domain DUF3429 PF11911.8 PFH32370.1 - 0.0034 17.7 10.2 0.0057 16.9 10.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Peptidase_S8 PF00082.22 PFH32371.1 - 3.2e-35 121.8 0.4 6.1e-35 120.9 0.4 1.4 1 0 0 1 1 1 1 Subtilase family DUF641 PF04859.12 PFH32372.1 - 0.0016 18.8 3.4 0.0026 18.1 3.4 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.9 PFH32372.1 - 0.026 14.5 9.6 0.41 10.7 4.0 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Orexin_rec2 PF03827.13 PFH32372.1 - 0.036 14.1 0.1 0.069 13.2 0.1 1.4 1 0 0 1 1 1 0 Orexin receptor type 2 DUF1664 PF07889.12 PFH32372.1 - 0.044 13.8 2.0 0.088 12.9 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4665 PF15679.5 PFH32372.1 - 0.1 13.2 0.5 0.41 11.3 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) dCache_3 PF14827.6 PFH32372.1 - 0.11 12.1 0.8 0.2 11.3 0.8 1.4 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase PilJ PF13675.6 PFH32372.1 - 0.13 12.3 0.8 0.22 11.6 0.2 1.7 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Jnk-SapK_ap_N PF09744.9 PFH32372.1 - 0.14 12.4 9.0 0.23 11.7 9.0 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Img2 PF05046.14 PFH32372.1 - 0.14 12.4 0.6 0.47 10.8 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Spc42p PF11544.8 PFH32372.1 - 0.28 11.2 4.2 0.6 10.1 0.5 2.3 1 1 1 2 2 2 0 Spindle pole body component Spc42p Muted PF14942.6 PFH32372.1 - 0.35 11.2 6.8 0.45 10.9 6.2 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein MIT PF04212.18 PFH32372.1 - 1.1 9.4 5.7 1.7 8.8 1.2 2.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain PHO4 PF01384.20 PFH32374.1 - 6e-117 390.5 4.1 8.6e-117 389.9 4.1 1.2 1 0 0 1 1 1 1 Phosphate transporter family Pkinase PF00069.25 PFH32376.1 - 9.3e-13 48.1 0.0 3.5e-11 43.0 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32376.1 - 5.2e-09 35.8 0.0 7.3e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH32376.1 - 8.4e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PFH32376.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Retrotran_gag_2 PF14223.6 PFH32376.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Kdo PF06293.14 PFH32376.1 - 0.1 12.0 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 PFH32377.1 - 2.5e-16 59.6 23.7 1.5e-10 40.5 16.7 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 PFH32378.1 - 4.5e-17 61.6 0.0 6.5e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 PFH32378.1 - 1.1e-07 31.8 4.0 1.1e-07 31.8 4.0 2.0 2 0 0 2 2 2 1 WW domain CTNNBL PF08216.11 PFH32380.1 - 4.6e-32 110.3 1.3 2.6e-31 107.9 1.3 2.4 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Cauli_AT PF03233.13 PFH32380.1 - 0.0088 16.0 1.3 1.6 8.7 0.0 2.8 2 0 0 2 2 2 1 Aphid transmission protein HEAT_2 PF13646.6 PFH32380.1 - 0.019 15.3 2.7 0.23 11.9 0.0 3.4 4 0 0 4 4 4 0 HEAT repeats Aconitase_B_N PF11791.8 PFH32380.1 - 0.046 13.8 0.3 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 Aconitate B N-terminal domain RasGEF_N_2 PF14663.6 PFH32380.1 - 0.066 13.6 3.3 0.26 11.7 0.1 3.2 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.23 PFH32380.1 - 0.077 13.1 2.2 0.19 11.8 0.0 2.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF2624 PF11116.8 PFH32380.1 - 7.2 7.6 7.7 28 5.7 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2624) Pkinase PF00069.25 PFH32381.1 - 4.2e-19 68.9 0.0 8.6e-17 61.4 0.0 3.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32381.1 - 1.9e-08 33.9 0.0 4.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Cyclin_N PF00134.23 PFH32381.1 - 9e-05 22.2 0.2 0.0024 17.6 0.1 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain CAP PF00188.26 PFH32382.1 - 0.0002 22.2 0.1 0.00026 21.8 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 PFH32383.1 - 2.5e-10 41.3 1.1 2.6e-10 41.2 0.1 1.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family CAP PF00188.26 PFH32384.1 - 2.1e-10 41.5 0.1 3.4e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF4179 PF13786.6 PFH32384.1 - 0.17 12.3 0.0 0.46 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) CAP PF00188.26 PFH32385.1 - 1.7e-11 45.0 0.3 3e-11 44.2 0.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family YlbD_coat PF14071.6 PFH32385.1 - 0.14 12.4 0.2 0.21 11.8 0.2 1.2 1 0 0 1 1 1 0 Putative coat protein DUF4179 PF13786.6 PFH32385.1 - 0.34 11.4 0.1 0.34 11.4 0.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) CAP PF00188.26 PFH32386.1 - 7.1e-11 43.0 0.4 1.5e-10 42.0 0.4 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Surface_antigen PF11054.8 PFH32386.1 - 0.0039 16.9 0.3 1.8 8.2 0.1 2.2 2 0 0 2 2 2 2 Sporozoite TA4 surface antigen CBS PF00571.28 PFH32388.1 - 5.6e-12 45.9 1.4 3.1e-06 27.5 0.1 4.3 5 0 0 5 5 5 2 CBS domain Ras PF00071.22 PFH32389.1 - 8.3e-32 110.0 0.1 2.4e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 PFH32389.1 - 1.3e-19 70.6 0.0 3.6e-19 69.1 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DnaJ PF00226.31 PFH32389.1 - 1.5e-17 63.4 0.0 3.1e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Arf PF00025.21 PFH32389.1 - 5.4e-10 39.0 0.0 8.5e-08 31.8 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PFH32389.1 - 0.0051 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 PFH32389.1 - 0.13 11.4 0.0 12 4.9 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit Gtr1_RagA PF04670.12 PFH32389.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DHHC PF01529.20 PFH32390.1 - 9e-25 87.3 14.0 9e-25 87.3 14.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 PFH32390.1 - 5.2e-18 65.4 0.9 1.2e-07 32.2 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PFH32390.1 - 2.8e-16 59.6 3.2 2.1e-07 31.3 0.2 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH32390.1 - 7.2e-10 38.3 3.8 0.1 13.2 0.0 5.2 5 1 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 PFH32390.1 - 1.8e-06 28.1 3.4 0.017 15.5 0.2 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 PFH32390.1 - 7.1e-05 23.0 2.4 0.053 13.9 0.1 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) PSI PF01437.25 PFH32390.1 - 1.9 9.1 9.7 0.21 12.2 4.5 2.1 2 0 0 2 2 2 0 Plexin repeat EF-hand_1 PF00036.32 PFH32392.1 - 3.1e-16 57.6 5.1 0.022 14.3 0.0 6.1 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 PFH32392.1 - 3.3e-15 56.3 5.0 1.1e-06 29.0 0.0 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PFH32392.1 - 1.8e-12 46.1 1.2 0.81 9.8 0.0 5.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 PFH32392.1 - 6.6e-09 34.9 3.9 0.081 12.5 0.0 5.4 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 PFH32392.1 - 3.8e-07 29.8 5.1 0.031 14.1 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain pair Glyco_hydro_19 PF00182.19 PFH32393.1 - 3.2e-09 37.0 0.5 8.7e-09 35.6 0.5 1.7 1 1 0 1 1 1 1 Chitinase class I DUF1764 PF08576.10 PFH32394.1 - 1.1 10.2 3.3 0.62 11.0 0.8 1.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Vir_act_alpha_C PF10400.9 PFH32395.1 - 0.066 13.9 3.4 0.12 13.1 0.4 2.7 3 1 0 3 3 3 0 Virulence activator alpha C-term SAS4 PF15460.6 PFH32395.1 - 0.76 9.9 4.3 0.46 10.6 0.2 2.7 4 0 0 4 4 4 0 Something about silencing, SAS, complex subunit 4 PEP_mutase PF13714.6 PFH32396.1 - 2.4e-51 174.5 0.4 2.8e-51 174.3 0.4 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 PFH32396.1 - 3.9e-16 58.6 0.2 5.6e-16 58.1 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Toprim_3 PF13362.6 PFH32396.1 - 0.091 13.1 0.4 0.87 10.0 0.0 2.3 2 0 0 2 2 2 0 Toprim domain Peptidase_C2 PF00648.21 PFH32397.1 - 2.4e-42 145.0 0.0 1.3e-41 142.6 0.0 1.9 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 PFH32397.1 - 5.4e-08 33.2 0.2 0.00017 21.9 0.0 3.7 3 1 0 3 3 3 2 Calpain large subunit, domain III Methyltransf_25 PF13649.6 PFH32398.1 - 7.2e-07 29.8 0.1 1.5e-05 25.6 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PFH32398.1 - 2.7e-05 24.7 0.0 0.00032 21.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 PFH32398.1 - 0.0002 21.0 0.0 0.0013 18.3 0.0 2.0 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 PFH32398.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 PFH32398.1 - 0.029 13.5 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 PFH32398.1 - 0.03 15.1 0.0 0.074 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RPA_interact_M PF14767.6 PFH32400.1 - 0.027 15.0 3.3 0.11 13.1 3.3 2.0 1 0 0 1 1 1 0 Replication protein A interacting middle OSTbeta PF15048.6 PFH32400.1 - 0.21 11.7 0.0 0.21 11.7 0.0 2.6 3 0 0 3 3 3 0 Organic solute transporter subunit beta protein SET PF00856.28 PFH32400.1 - 0.52 10.7 0.0 0.52 10.7 0.0 3.4 3 2 0 3 3 3 0 SET domain CDC45 PF02724.14 PFH32401.1 - 4.1 5.6 6.4 13 3.9 6.4 1.8 1 0 0 1 1 1 0 CDC45-like protein Cluap1 PF10234.9 PFH32402.1 - 7.4e-55 186.2 0.3 1.5e-54 185.2 0.0 1.6 2 0 0 2 2 2 1 Clusterin-associated protein-1 ERM PF00769.19 PFH32402.1 - 0.00073 19.4 12.5 0.00073 19.4 12.5 1.7 1 1 0 1 1 1 1 Ezrin/radixin/moesin family FAM181 PF15238.6 PFH32402.1 - 5 6.9 9.1 0.22 11.3 3.1 1.7 2 0 0 2 2 2 0 FAM181 CS PF04969.16 PFH32403.1 - 2.2e-06 28.6 0.0 5e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 CS domain Thioredoxin PF00085.20 PFH32404.1 - 1.7e-30 105.0 0.3 1.9e-30 104.9 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PFH32404.1 - 4.3e-06 27.1 0.1 1.1e-05 25.9 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PFH32404.1 - 0.00013 22.2 0.0 0.00026 21.2 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 PFH32404.1 - 0.00013 21.7 0.1 0.00015 21.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 PFH32404.1 - 0.00049 20.2 0.0 0.00063 19.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 PFH32404.1 - 0.00054 19.9 0.1 0.00081 19.3 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 PFH32404.1 - 0.00079 18.9 0.0 0.00079 18.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 PFH32404.1 - 0.011 15.4 0.1 0.022 14.5 0.1 1.5 1 1 1 2 2 2 0 Redoxin Glutaredoxin PF00462.24 PFH32404.1 - 0.089 13.0 0.2 0.16 12.2 0.2 1.5 1 1 0 1 1 1 0 Glutaredoxin WD40 PF00400.32 PFH32405.1 - 5e-08 33.5 22.6 0.00038 21.2 0.2 7.2 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH32405.1 - 0.00054 20.2 0.4 5 7.5 0.0 5.0 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain SerH PF06873.11 PFH32405.1 - 0.048 12.5 0.1 0.086 11.6 0.1 1.3 1 0 0 1 1 1 0 Cell surface immobilisation antigen SerH Arm PF00514.23 PFH32405.1 - 0.076 13.1 0.2 0.2 11.8 0.2 1.7 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Mcl1_mid PF12341.8 PFH32405.1 - 0.095 12.0 0.0 6 6.1 0.0 2.3 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region Tme5_EGF_like PF09064.10 PFH32406.1 - 0.11 12.4 1.6 0.27 11.2 1.6 1.6 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like Sua5_yciO_yrdC PF01300.18 PFH32407.1 - 4.2e-30 104.6 0.0 2.3e-28 98.9 0.0 2.9 2 1 0 2 2 2 1 Telomere recombination SUA5 PF03481.13 PFH32407.1 - 2.1e-09 38.0 0.7 2.1e-09 38.0 0.7 2.2 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding SR-25 PF10500.9 PFH32407.1 - 0.014 15.1 1.4 0.014 15.1 1.4 3.2 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein zf-RING_2 PF13639.6 PFH32409.1 - 2.4e-12 47.0 4.3 2.4e-12 47.0 4.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 PFH32409.1 - 5.9e-10 38.7 3.1 5.9e-10 38.7 3.1 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PFH32409.1 - 4.2e-08 32.9 3.8 4.2e-08 32.9 3.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PFH32409.1 - 6.1e-08 32.4 2.3 6.1e-08 32.4 2.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH32409.1 - 6.6e-08 32.4 1.0 6.6e-08 32.4 1.0 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 PFH32409.1 - 1.4e-06 28.4 6.6 4.6e-06 26.8 6.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PFH32409.1 - 7.4e-05 22.6 2.6 7.4e-05 22.6 2.6 1.6 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PFH32409.1 - 0.00013 21.7 5.1 0.00013 21.7 5.1 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 PFH32409.1 - 0.0015 18.1 3.3 0.0028 17.2 3.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 PFH32409.1 - 0.0016 18.2 2.4 0.0016 18.2 2.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_16 PF17034.5 PFH32409.1 - 0.041 14.1 0.4 0.086 13.1 0.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family zf-ANAPC11 PF12861.7 PFH32409.1 - 0.074 13.1 0.7 0.14 12.3 0.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 PFH32409.1 - 0.28 11.4 4.9 0.61 10.3 4.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 PFH32409.1 - 1 9.5 3.0 1.8 8.7 3.0 1.4 1 0 0 1 1 1 0 RING-variant domain ER_lumen_recept PF00810.18 PFH32410.1 - 1.4e-31 110.3 6.6 1.4e-31 110.3 6.6 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor AC_N PF16214.5 PFH32410.1 - 5.8 5.9 6.2 10 5.1 6.2 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region PepSY_TM PF03929.16 PFH32412.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.4 2 1 0 2 2 2 0 PepSY-associated TM region Methyltransf_4 PF02390.17 PFH32414.1 - 6.4e-48 162.5 0.0 7.9e-48 162.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 PFH32414.1 - 0.00068 20.3 0.0 0.0013 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH32414.1 - 0.028 15.1 0.0 0.064 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 PFH32414.1 - 0.03 15.0 0.0 0.15 12.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.13 PFH32414.1 - 0.071 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 PFH32414.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.6 PFH32414.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 PFH32414.1 - 0.24 10.6 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ECH_2 PF16113.5 PFH32415.1 - 1.2e-38 133.5 0.0 4.6e-37 128.3 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 PFH32415.1 - 7.5e-08 32.0 0.0 3.6e-07 29.8 0.0 2.0 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase PhoU PF01895.19 PFH32415.1 - 0.15 12.5 0.0 0.44 11.0 0.0 1.7 1 0 0 1 1 1 0 PhoU domain GAS PF13851.6 PFH32416.1 - 0.002 17.5 11.6 0.002 17.5 11.6 4.9 1 1 2 4 4 4 2 Growth-arrest specific micro-tubule binding zf-C6H2 PF15801.5 PFH32417.1 - 9.4e-11 41.9 9.4 1.7e-10 41.0 9.4 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 PFH32417.1 - 0.0015 18.6 8.7 0.003 17.6 8.7 1.5 1 0 0 1 1 1 1 MYND finger SNARE PF05739.19 PFH32417.1 - 0.1 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 SNARE domain Rbsn PF11464.8 PFH32417.1 - 0.19 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Rabenosyn Rab binding domain PDEase_I PF00233.19 PFH32418.1 - 9.3e-67 225.2 0.5 5e-66 222.8 0.2 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 PFH32418.1 - 0.099 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 HD domain COX2_TM PF02790.15 PFH32419.1 - 0.0016 18.6 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain WD40 PF00400.32 PFH32421.1 - 4e-16 59.1 7.8 9.2e-06 26.3 0.7 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH32421.1 - 2.2e-06 27.9 0.1 2.1 8.7 0.0 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PFH32421.1 - 0.11 11.4 0.0 9.8 5.0 0.0 2.5 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase PF00069.25 PFH32422.1 - 1.6e-49 168.7 0.0 2.3e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32422.1 - 1.6e-34 119.3 0.0 2.5e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH32422.1 - 1.2e-08 34.7 0.0 2.4e-08 33.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like NPV_P10 PF05531.12 PFH32422.1 - 0.081 13.4 0.0 0.7 10.4 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PrmA PF06325.13 PFH32423.1 - 1.4e-07 31.2 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PFH32423.1 - 7.4e-07 29.8 0.0 6.3e-06 26.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.16 PFH32423.1 - 9.4e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.12 PFH32423.1 - 9.2e-05 23.0 0.0 0.00036 21.1 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 PFH32423.1 - 0.00021 20.9 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 PFH32423.1 - 0.0022 17.9 0.0 0.006 16.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PFH32423.1 - 0.005 16.7 0.0 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PRMT5_C PF17286.2 PFH32423.1 - 0.0074 16.2 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Cons_hypoth95 PF03602.15 PFH32423.1 - 0.0087 15.7 0.1 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 PFH32423.1 - 0.019 15.7 0.0 0.48 11.2 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 PFH32423.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HECT PF00632.25 PFH32424.1 - 1.3e-87 294.2 0.0 1.7e-87 293.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DER1 PF04511.15 PFH32425.1 - 2.6e-19 69.9 0.4 3.3e-19 69.6 0.4 1.1 1 0 0 1 1 1 1 Der1-like family SSF PF00474.17 PFH32426.1 - 1.7e-12 46.9 24.8 1.7e-12 46.9 24.8 2.0 1 1 1 2 2 2 1 Sodium:solute symporter family OppC_N PF12911.7 PFH32426.1 - 1.1 9.3 6.0 0.49 10.4 0.6 3.3 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C TPR_16 PF13432.6 PFH32429.1 - 2.2e-08 34.6 26.9 0.0039 17.8 3.1 7.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 PFH32429.1 - 1.2e-06 28.2 23.1 0.025 14.7 0.1 8.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 PFH32429.1 - 8.6e-06 26.2 17.8 0.13 12.8 0.6 6.1 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 PFH32429.1 - 1e-05 25.5 1.3 0.44 11.0 0.0 5.7 5 1 1 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH32429.1 - 2e-05 24.7 14.7 0.0039 17.4 0.2 5.1 5 1 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 PFH32429.1 - 2.6e-05 24.4 26.9 0.0045 17.2 0.1 7.1 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 PFH32429.1 - 4.7e-05 23.0 7.1 1 9.3 0.4 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 PFH32429.1 - 0.003 17.9 1.2 0.065 13.6 0.1 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 PFH32429.1 - 0.012 16.4 27.7 3.6 8.6 0.3 7.4 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH32429.1 - 0.013 16.1 12.4 1.3 9.8 0.5 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 PFH32429.1 - 0.027 14.7 0.6 24 5.4 0.3 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 PFH32429.1 - 0.28 11.2 0.7 59 3.8 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PFH32429.1 - 2.6 8.2 5.5 1.2 9.2 0.1 3.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 PFH32429.1 - 5.9 7.2 13.5 49 4.3 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Histone PF00125.24 PFH32430.1 - 4.5e-15 56.2 0.2 5.5e-15 55.9 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PFH32430.1 - 0.00026 21.2 0.2 0.00051 20.3 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 PFH32430.1 - 0.00035 21.0 0.0 0.0006 20.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Na_H_Exchanger PF00999.21 PFH32431.1 - 5e-50 170.4 42.5 5e-50 170.4 42.5 1.6 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family DUF4396 PF14342.6 PFH32431.1 - 0.51 10.7 9.1 1.4 9.3 9.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) CorA PF01544.18 PFH32432.1 - 1.4e-08 34.4 0.1 3.5e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein TPR_17 PF13431.6 PFH32433.1 - 0.00024 21.3 8.3 0.21 12.1 0.0 4.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 PFH32433.1 - 0.0027 18.2 19.7 0.56 10.7 0.4 6.0 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 PFH32433.1 - 0.003 17.5 21.1 0.12 12.6 0.2 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 PFH32433.1 - 0.017 15.4 1.5 0.017 15.4 1.5 6.2 5 2 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH32433.1 - 0.036 14.3 5.5 2.6 8.3 0.0 4.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PFH32433.1 - 0.038 14.0 9.5 0.2 11.8 0.1 5.2 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 PFH32433.1 - 0.066 13.5 8.8 0.25 11.6 0.0 5.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 PFH32433.1 - 0.28 11.1 11.5 0.18 11.7 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 PFH32433.1 - 0.42 11.5 38.2 9.2 7.4 0.6 10.0 5 3 2 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 PFH32433.1 - 1.1 9.0 3.5 85 3.0 0.0 4.3 5 0 0 5 5 5 0 TPR repeat DivIC PF04977.15 PFH32434.1 - 1.1e-06 28.3 0.1 1.8e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Septum formation initiator bZIP_1 PF00170.21 PFH32434.1 - 6.4e-06 26.2 0.8 1.1e-05 25.4 0.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor ZapB PF06005.12 PFH32434.1 - 2.3e-05 24.7 1.0 4.7e-05 23.7 1.0 1.5 1 0 0 1 1 1 1 Cell division protein ZapB HALZ PF02183.18 PFH32434.1 - 0.00017 21.7 0.8 0.00051 20.2 0.4 2.0 1 1 1 2 2 2 1 Homeobox associated leucine zipper bZIP_2 PF07716.15 PFH32434.1 - 0.00054 20.0 1.0 0.0011 19.0 1.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Cnn_1N PF07989.11 PFH32434.1 - 0.00055 20.0 0.5 0.00076 19.6 0.1 1.5 2 0 0 2 2 1 1 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 PFH32434.1 - 0.001 19.2 0.2 0.0011 19.1 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus TSC22 PF01166.18 PFH32434.1 - 0.0012 19.2 0.7 0.002 18.4 0.7 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family YscO PF07321.12 PFH32434.1 - 0.002 18.1 0.2 0.0028 17.6 0.2 1.3 1 0 0 1 1 1 1 Type III secretion protein YscO CENP-F_leu_zip PF10473.9 PFH32434.1 - 0.0033 17.5 0.5 0.0058 16.7 0.5 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 PFH32434.1 - 0.0036 17.7 3.0 0.004 17.5 0.5 2.0 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Bap31_Bap29_C PF18035.1 PFH32434.1 - 0.0038 17.2 1.5 0.53 10.3 0.8 2.4 1 1 1 2 2 2 2 Bap31/Bap29 cytoplasmic coiled-coil domain DUF1640 PF07798.11 PFH32434.1 - 0.0056 16.8 0.2 0.012 15.7 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) DUF3450 PF11932.8 PFH32434.1 - 0.0064 15.8 0.4 0.0064 15.8 0.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) JIP_LZII PF16471.5 PFH32434.1 - 0.009 16.2 1.1 0.019 15.1 1.1 1.7 1 1 0 1 1 1 1 JNK-interacting protein leucine zipper II WEMBL PF05701.11 PFH32434.1 - 0.0092 14.7 0.1 0.0092 14.7 0.1 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light TMF_DNA_bd PF12329.8 PFH32434.1 - 0.0093 15.9 1.6 0.0093 15.9 1.6 1.5 2 0 0 2 2 1 1 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.6 PFH32434.1 - 0.014 15.5 2.7 1.3 9.1 0.7 2.4 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Shugoshin_N PF07558.11 PFH32434.1 - 0.014 15.2 0.4 0.62 10.0 0.1 2.2 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region Tup_N PF08581.10 PFH32434.1 - 0.016 15.5 0.3 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 Tup N-terminal Seryl_tRNA_N PF02403.22 PFH32434.1 - 0.017 15.4 0.2 0.03 14.6 0.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 PFH32434.1 - 0.019 15.0 1.0 0.019 15.0 0.2 1.4 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein DUF3053 PF11254.8 PFH32434.1 - 0.02 14.5 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Spc7 PF08317.11 PFH32434.1 - 0.02 13.8 0.1 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 PFH32434.1 - 0.026 14.8 0.7 0.094 13.1 0.5 1.8 1 1 1 2 2 2 0 Csm1 N-terminal domain Uds1 PF15456.6 PFH32434.1 - 0.027 14.6 0.7 0.041 14.1 0.7 1.3 1 0 0 1 1 1 0 Up-regulated During Septation CCDC92 PF14916.6 PFH32434.1 - 0.028 14.2 0.4 0.45 10.3 0.3 2.7 2 1 0 2 2 2 0 Coiled-coil domain of unknown function Phasin PF05597.11 PFH32434.1 - 0.029 14.4 0.2 0.56 10.2 0.0 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) WXG100 PF06013.12 PFH32434.1 - 0.03 14.5 0.2 0.059 13.6 0.2 1.4 1 0 0 1 1 1 0 Proteins of 100 residues with WXG PI3K_P85_iSH2 PF16454.5 PFH32434.1 - 0.034 13.8 1.6 0.077 12.6 1.6 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain GAS PF13851.6 PFH32434.1 - 0.034 13.5 1.6 0.034 13.5 0.3 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.13 PFH32434.1 - 0.039 14.0 0.4 0.077 13.1 0.1 1.5 2 0 0 2 2 2 0 DivIVA protein KLRAQ PF10205.9 PFH32434.1 - 0.04 14.2 0.6 0.07 13.4 0.1 1.5 2 0 0 2 2 1 0 Predicted coiled-coil domain-containing protein GrpE PF01025.19 PFH32434.1 - 0.042 13.5 1.3 0.18 11.5 0.2 1.9 2 0 0 2 2 2 0 GrpE DUF3160 PF11369.8 PFH32434.1 - 0.043 12.3 0.0 0.053 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) CCDC106 PF15794.5 PFH32434.1 - 0.044 13.5 0.5 0.06 13.0 0.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Clp_N PF02861.20 PFH32434.1 - 0.048 13.8 0.0 2.6 8.2 0.0 3.1 4 0 0 4 4 3 0 Clp amino terminal domain, pathogenicity island component DUF1192 PF06698.11 PFH32434.1 - 0.058 13.5 1.8 0.46 10.6 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) bZIP_Maf PF03131.17 PFH32434.1 - 0.069 13.7 1.6 0.31 11.6 0.5 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor APC_N_CC PF16689.5 PFH32434.1 - 0.073 13.1 0.6 4.9 7.3 0.1 2.5 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF2730 PF10805.8 PFH32434.1 - 0.085 13.0 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) LPP PF04728.13 PFH32434.1 - 0.093 13.1 0.9 0.23 11.8 0.9 1.7 1 1 0 1 1 1 0 Lipoprotein leucine-zipper Atg14 PF10186.9 PFH32434.1 - 0.11 11.5 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 PFH32434.1 - 0.12 12.8 2.9 0.16 12.5 2.9 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region NYD-SP28_assoc PF14775.6 PFH32434.1 - 0.2 11.8 2.1 0.35 11.0 0.2 2.3 2 1 1 3 3 3 0 Sperm tail C-terminal domain WD40_alt PF14077.6 PFH32434.1 - 0.31 10.9 1.2 11 6.0 0.2 2.2 1 1 1 2 2 2 0 Alternative WD40 repeat motif Dynamin_N PF00350.23 PFH32435.1 - 0.022 14.8 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Dynamin family TniB PF05621.11 PFH32435.1 - 0.038 13.4 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein MMR_HSR1 PF01926.23 PFH32435.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Suf PF05843.14 PFH32436.1 - 4.3e-08 33.5 14.1 9.1e-06 25.9 0.1 5.2 4 2 2 6 6 6 2 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 PFH32436.1 - 2.3e-05 24.4 8.5 2.3 8.2 0.0 6.6 6 1 1 7 7 7 2 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 PFH32436.1 - 0.00032 20.9 20.1 0.013 15.8 0.2 7.7 7 3 3 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 PFH32436.1 - 0.0018 18.0 0.9 0.036 13.9 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 PFH32436.1 - 0.0035 17.2 2.9 0.053 13.6 0.3 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat HSP90 PF00183.18 PFH32436.1 - 0.0045 15.9 0.3 0.0045 15.9 0.3 1.8 2 0 0 2 2 2 1 Hsp90 protein TPR_8 PF13181.6 PFH32436.1 - 0.037 14.2 13.6 0.2 12.0 0.1 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 PFH32436.1 - 0.039 14.1 0.2 0.039 14.1 0.2 7.0 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 PFH32436.1 - 0.16 12.9 0.2 0.21 12.5 0.2 11.5 12 3 2 14 14 12 0 Tetratricopeptide repeat TPR_16 PF13432.6 PFH32436.1 - 0.31 11.7 21.6 0.82 10.4 0.4 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Folliculin PF11704.8 PFH32436.1 - 2.4 8.0 6.4 10 6.0 0.7 2.4 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport RPN7 PF10602.9 PFH32436.1 - 3.3 7.4 12.8 1.2 8.9 0.2 3.9 4 1 1 5 5 4 0 26S proteasome subunit RPN7 NrsF PF06532.11 PFH32437.1 - 0.0076 16.0 0.1 0.0076 16.0 0.1 2.1 2 0 0 2 2 2 1 Negative regulator of sigma F DUF3682 PF12446.8 PFH32437.1 - 0.035 14.6 0.1 0.054 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) MgtE PF01769.16 PFH32437.1 - 0.19 12.1 3.6 2.9 8.3 0.0 2.6 2 1 1 3 3 3 0 Divalent cation transporter Hydrolase_4 PF12146.8 PFH32438.1 - 2.3e-26 92.6 0.1 6.4e-26 91.1 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PFH32438.1 - 5.5e-06 26.2 0.0 0.00017 21.3 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 PFH32438.1 - 0.00017 21.5 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 PFH32438.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF900 PF05990.12 PFH32438.1 - 0.025 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) vATP-synt_E PF01991.18 PFH32440.1 - 1.5e-59 200.7 2.1 2.2e-59 200.2 2.1 1.2 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4239 PF14023.6 PFH32440.1 - 0.0018 18.1 6.0 0.0018 18.1 6.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4239) Helicase_PWI PF18149.1 PFH32440.1 - 0.0035 17.5 2.4 0.0035 17.5 2.4 2.0 2 0 0 2 2 2 1 N-terminal helicase PWI domain Ku_PK_bind PF08785.11 PFH32440.1 - 0.051 13.7 5.3 0.14 12.3 5.3 1.8 1 1 0 1 1 1 0 Ku C terminal domain like IL13 PF03487.13 PFH32440.1 - 0.11 12.2 1.3 0.46 10.3 0.5 2.1 2 0 0 2 2 2 0 Interleukin-13 DUF445 PF04286.12 PFH32440.1 - 0.19 11.5 9.4 0.22 11.3 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Baculo_LEF-11 PF06385.12 PFH32440.1 - 0.29 11.6 2.5 0.55 10.8 2.5 1.4 1 0 0 1 1 1 0 Baculovirus LEF-11 protein DUF4047 PF13256.6 PFH32440.1 - 2.8 8.2 8.3 2.6 8.3 4.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) ERCC4 PF02732.15 PFH32441.1 - 5.6e-09 36.4 0.0 1.1e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain mRNA_cap_enzyme PF01331.19 PFH32442.1 - 2.2e-39 135.3 0.0 1.5e-25 90.2 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 PFH32442.1 - 6.6e-12 46.0 0.0 2.1e-11 44.4 0.0 1.8 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain Cyclin PF08613.11 PFH32443.1 - 1.8e-36 125.9 0.4 3.5e-36 125.0 0.4 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 PFH32443.1 - 2.4e-09 37.0 0.0 4.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Kelch_4 PF13418.6 PFH32444.1 - 9.2e-18 64.0 6.6 0.0015 18.5 0.0 6.4 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PFH32444.1 - 6.9e-17 61.0 0.0 0.0016 18.3 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 PFH32444.1 - 2e-14 53.4 1.8 0.0018 18.5 0.0 5.5 4 0 0 4 4 4 3 Galactose oxidase, central domain HATPase_c_3 PF13589.6 PFH32444.1 - 4.2e-10 39.6 0.0 8.7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_6 PF13964.6 PFH32444.1 - 6.5e-07 29.4 0.2 0.0017 18.6 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 PFH32444.1 - 8.8e-07 28.4 0.0 0.035 13.7 0.0 4.3 4 0 0 4 4 4 2 Kelch motif HATPase_c PF02518.26 PFH32444.1 - 0.045 14.3 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_2 PF07646.15 PFH32444.1 - 0.13 12.3 0.3 6.5 6.9 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Acetyltransf_1 PF00583.25 PFH32445.1 - 1.3e-12 47.9 0.0 2.2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PFH32445.1 - 1.5e-06 28.6 0.0 2.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PFH32445.1 - 5.8e-06 26.3 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PFH32445.1 - 0.00088 19.4 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PFH32445.1 - 0.0011 19.6 0.0 0.0019 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PFH32445.1 - 0.034 14.3 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cytochrom_C PF00034.21 PFH32446.1 - 1.2e-05 26.4 0.1 2.6e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 PFH32446.1 - 0.0099 16.2 1.0 0.02 15.2 1.0 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 PFH32446.1 - 0.011 15.4 0.0 0.035 13.8 0.0 1.7 2 0 0 2 2 2 0 Cytochrome c-550 domain Peptidase_M24 PF00557.24 PFH32447.1 - 2.2e-36 125.6 0.1 3.1e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 PGA2 PF07543.12 PFH32447.1 - 0.016 15.1 3.8 0.016 15.1 3.8 1.6 2 0 0 2 2 2 0 Protein trafficking PGA2 SRP-alpha_N PF04086.13 PFH32447.1 - 0.091 12.7 7.8 0.37 10.7 7.5 1.9 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal TFIIF_alpha PF05793.12 PFH32447.1 - 0.13 10.8 10.7 0.18 10.4 10.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 PFH32447.1 - 0.23 9.7 3.5 0.31 9.3 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1682 PF07946.14 PFH32447.1 - 2.2 7.4 4.4 4.8 6.3 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PBP1_TM PF14812.6 PFH32447.1 - 2.4 8.6 5.1 5.4 7.5 5.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3381 PF11861.8 PFH32447.1 - 9.7 6.0 11.0 21 4.9 11.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Radical_SAM_C PF16199.5 PFH32449.1 - 1.7e-19 69.6 0.0 4.7e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 PFH32449.1 - 2e-15 57.5 0.0 6e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 PFH32449.1 - 0.001 19.3 0.1 0.0027 17.9 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PFH32449.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CNRIP1 PF15043.6 PFH32449.1 - 0.22 11.0 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 CB1 cannabinoid receptor-interacting protein 1 PDCD2_C PF04194.13 PFH32450.1 - 1.2e-41 142.7 0.2 2.1e-41 141.9 0.2 1.4 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain GFO_IDH_MocA PF01408.22 PFH32451.1 - 8.3e-05 23.4 0.0 0.00031 21.6 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Ribosomal_S5 PF00333.20 PFH32452.1 - 1.3e-29 101.9 0.8 2.2e-29 101.2 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 PFH32452.1 - 1.9e-22 78.5 0.0 3.3e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 PFH32452.1 - 6.6 7.4 9.3 16 6.1 9.3 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 LOH1CR12 PF10158.9 PFH32453.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Tumour suppressor protein DUF1769 PF08588.10 PFH32454.1 - 1.5e-08 34.7 0.0 3.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Cas_GSU0053 PF09617.10 PFH32454.1 - 0.04 13.9 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) UbiA PF01040.18 PFH32454.1 - 0.13 11.5 1.2 0.21 10.9 1.2 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family Vps51 PF08700.11 PFH32455.1 - 2.6e-19 69.1 0.0 6.7e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 PFH32455.1 - 8.3e-08 32.3 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 PFH32455.1 - 0.00014 20.7 0.4 0.0004 19.2 0.4 1.8 1 0 0 1 1 1 1 Dor1-like family COG2 PF06148.11 PFH32455.1 - 0.00047 20.3 1.3 0.00047 20.3 1.3 2.4 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.13 PFH32455.1 - 0.029 13.0 0.3 0.041 12.4 0.3 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 IFT81_CH PF18383.1 PFH32456.1 - 2.4e-12 47.2 2.1 5.4e-12 46.0 0.0 2.6 3 1 0 3 3 3 1 Intraflagellar transport 81 calponin homology domain Syntaxin-6_N PF09177.11 PFH32456.1 - 0.02 15.5 1.6 0.02 15.5 1.6 3.5 3 1 0 3 3 3 0 Syntaxin 6, N-terminal DUF2779 PF11074.8 PFH32456.1 - 0.068 13.6 0.2 0.6 10.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) Bacillus_HBL PF05791.11 PFH32456.1 - 0.082 12.7 0.3 0.082 12.7 0.3 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Ank_2 PF12796.7 PFH32457.1 - 7.4e-31 106.6 0.0 4.2e-19 68.9 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PFH32457.1 - 1.5e-23 82.5 0.6 5.7e-11 42.4 0.1 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PFH32457.1 - 1.5e-21 76.5 0.2 5.6e-13 49.1 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH32457.1 - 1.6e-19 67.9 0.6 8.9e-06 25.7 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 PFH32457.1 - 3.8e-18 65.0 0.0 5.6e-05 23.4 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat ABC_membrane PF00664.23 PFH32458.1 - 1e-31 110.6 15.5 1.4e-23 83.9 0.0 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 PFH32458.1 - 6.4e-31 107.7 0.0 2.4e-16 60.5 0.0 3.3 2 1 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 PFH32458.1 - 6.7e-07 29.0 0.0 0.022 14.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 PFH32458.1 - 3.6e-06 27.0 0.7 0.042 13.7 0.1 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 PFH32458.1 - 1.5e-05 25.0 0.1 0.011 15.8 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 PFH32458.1 - 2.1e-05 24.8 1.1 0.045 14.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 PFH32458.1 - 2.2e-05 24.9 9.1 0.0006 20.2 0.5 3.5 2 2 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 PFH32458.1 - 4.3e-05 22.6 0.1 0.0035 16.3 0.1 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 PFH32458.1 - 0.00018 22.0 0.0 0.17 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PFH32458.1 - 0.00022 21.8 0.0 0.19 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 PFH32458.1 - 0.00022 21.2 0.1 0.66 9.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 PFH32458.1 - 0.00027 21.1 0.1 0.071 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 PFH32458.1 - 0.00044 19.7 0.2 0.024 14.0 0.3 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Rad17 PF03215.15 PFH32458.1 - 0.00071 19.5 0.4 0.002 18.1 0.0 1.8 2 0 0 2 2 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 PFH32458.1 - 0.00072 19.0 0.4 0.22 10.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 PFH32458.1 - 0.0017 17.5 0.0 0.46 9.5 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 PFH32458.1 - 0.0022 17.8 0.1 2.9 7.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 PFH32458.1 - 0.0022 18.4 1.0 0.0097 16.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 PFH32458.1 - 0.0022 18.1 0.3 0.48 10.5 0.1 2.4 2 0 0 2 2 2 1 Dynamin family cobW PF02492.19 PFH32458.1 - 0.0041 16.7 0.4 1.8 8.1 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 PFH32458.1 - 0.0042 16.6 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 PFH32458.1 - 0.005 17.0 1.4 0.011 15.9 1.4 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_5 PF07728.14 PFH32458.1 - 0.0051 16.8 0.9 0.35 10.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 PFH32458.1 - 0.0067 16.0 0.0 0.31 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 PFH32458.1 - 0.0072 15.5 0.2 0.42 9.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 PFH32458.1 - 0.009 15.3 0.1 1.7 7.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 PFH32458.1 - 0.015 15.6 0.4 1.5 9.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 PFH32458.1 - 0.015 15.2 1.5 3.9 7.4 0.4 2.5 2 0 0 2 2 2 0 NACHT domain Viral_helicase1 PF01443.18 PFH32458.1 - 0.016 14.9 0.4 0.69 9.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SMC_N PF02463.19 PFH32458.1 - 0.018 14.5 0.0 5 6.5 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 PFH32458.1 - 0.031 14.7 0.2 2.4 8.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 PFH32458.1 - 0.074 13.0 0.1 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 PFH32458.1 - 0.22 11.3 0.0 0.51 10.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 PFH32458.1 - 0.27 10.9 0.0 26 4.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.6 PFH32458.1 - 0.79 10.1 4.7 1.2 9.6 0.0 3.1 4 0 0 4 4 3 0 AAA domain DUF1664 PF07889.12 PFH32460.1 - 0.038 14.0 0.9 0.14 12.2 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3802 PF12290.8 PFH32460.1 - 0.35 11.4 1.5 0.46 11.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) Rft-1 PF04506.13 PFH32461.1 - 7.2e-25 87.7 3.0 3.2e-10 39.4 0.1 4.7 4 1 0 4 4 4 4 Rft protein F-box-like PF12937.7 PFH32462.1 - 5.9e-05 22.9 2.0 0.00018 21.3 2.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PFH32462.1 - 0.047 13.6 0.2 0.14 12.1 0.2 1.9 1 0 0 1 1 1 0 F-box domain Beta-Casp PF10996.8 PFH32464.1 - 1.8e-22 79.7 0.0 3.4e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 PFH32464.1 - 1.9e-16 59.7 0.0 4.2e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 PFH32464.1 - 5.3e-11 42.3 0.0 1.3e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 PFH32464.1 - 1.2e-07 31.9 0.2 0.0027 17.7 0.1 3.1 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PFH32464.1 - 0.00018 21.1 0.2 0.0049 16.4 0.0 2.7 3 0 0 3 3 3 1 Beta-lactamase superfamily domain NGP1NT PF08153.12 PFH32465.1 - 1.1e-32 113.0 0.0 2.5e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 PFH32465.1 - 9.2e-17 61.2 0.0 1.4e-13 50.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 PFH32465.1 - 5.2e-07 29.3 0.0 0.002 17.7 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PFH32465.1 - 1.8e-06 27.9 0.0 4.4e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 PFH32465.1 - 0.00026 20.6 0.0 0.11 12.0 0.0 3.2 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.21 PFH32465.1 - 0.0032 16.9 0.0 2.5 7.5 0.1 2.5 1 1 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 PFH32465.1 - 0.031 14.3 2.1 0.53 10.3 0.0 3.3 3 1 1 4 4 4 0 Dynamin family AAA_16 PF13191.6 PFH32465.1 - 0.4 11.0 0.0 0.4 11.0 0.0 2.7 3 1 0 3 3 3 0 AAA ATPase domain zf-Nse PF11789.8 PFH32466.1 - 1.9e-13 50.0 0.2 3.3e-13 49.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 PFH32466.1 - 1.3e-05 25.1 0.1 3.2e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 PFH32466.1 - 0.037 14.4 0.1 0.079 13.3 0.1 1.6 1 0 0 1 1 1 0 Ring finger domain ABC_tran PF00005.27 PFH32467.1 - 4.5e-15 56.4 0.0 5.1e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 PFH32467.1 - 5.2e-07 29.8 3.8 0.0095 15.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 PFH32467.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 PFH32467.1 - 0.0014 18.3 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 PFH32467.1 - 0.0042 16.6 0.1 2.3 7.6 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 PFH32467.1 - 0.0051 16.9 0.0 0.0078 16.3 0.0 1.2 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 PFH32467.1 - 0.0086 16.0 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 PFH32467.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 PFH32467.1 - 0.21 12.1 0.1 0.33 11.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PFH32467.1 - 0.23 11.1 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 PFH32467.1 - 0.24 11.1 0.1 0.34 10.6 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain XRN_N PF03159.18 PFH32469.1 - 4.4e-97 324.3 0.0 4.4e-97 324.3 0.0 2.1 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PFH32469.1 - 4.2e-94 316.0 0.0 8.8e-43 146.9 0.0 3.6 3 1 0 3 3 3 3 Xrn1 helical domain DSPc PF00782.20 PFH32470.1 - 1.2e-07 31.6 0.0 2.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PFH32470.1 - 0.00077 19.5 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 PFH32470.1 - 0.0016 18.0 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPS PF01242.19 PFH32471.1 - 1.1e-18 67.4 0.0 2.9e-18 66.0 0.0 1.6 2 0 0 2 2 2 1 6-pyruvoyl tetrahydropterin synthase EI24 PF07264.11 PFH32472.1 - 0.0039 17.5 3.1 0.0099 16.1 3.2 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LapA_dom PF06305.11 PFH32472.1 - 1.2 9.0 7.7 0.12 12.2 1.2 2.3 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain CS PF04969.16 PFH32473.1 - 4.1e-13 50.2 0.3 6.7e-13 49.5 0.3 1.4 1 0 0 1 1 1 1 CS domain SGS PF05002.15 PFH32473.1 - 5.3e-05 23.2 0.2 0.00013 22.0 0.2 1.6 1 0 0 1 1 1 1 SGS domain Siah-Interact_N PF09032.11 PFH32473.1 - 0.022 15.1 0.1 0.076 13.3 0.1 2.0 1 0 0 1 1 1 0 Siah interacting protein, N terminal IIGP PF05049.13 PFH32473.1 - 0.024 13.7 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) SAG PF04092.13 PFH32474.1 - 8.7e-43 146.3 7.1 4.1e-21 76.1 0.0 3.1 2 1 1 3 3 3 3 SRS domain SAG PF04092.13 PFH32475.1 - 2.8e-42 144.6 13.8 2.8e-21 76.7 3.4 2.1 2 0 0 2 2 2 2 SRS domain Pilin PF00114.19 PFH32475.1 - 0.02 15.8 6.0 0.032 15.2 0.9 2.5 2 0 0 2 2 2 0 Pilin (bacterial filament) SAG PF04092.13 PFH32476.1 - 2e-35 122.4 11.4 5.8e-21 75.7 3.2 2.0 2 0 0 2 2 2 2 SRS domain Pilin PF00114.19 PFH32476.1 - 0.55 11.2 5.1 0.36 11.8 0.8 2.2 2 0 0 2 2 2 0 Pilin (bacterial filament) SAG PF04092.13 PFH32477.1 - 1.8e-31 109.7 8.5 9e-19 68.6 0.7 2.1 2 0 0 2 2 2 2 SRS domain EF-hand_7 PF13499.6 PFH32478.1 - 2.2e-10 40.8 2.2 0.00034 21.0 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PFH32478.1 - 3.5e-08 32.4 3.0 6e-05 22.3 1.5 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 PFH32478.1 - 9.6e-08 31.4 3.7 0.018 14.9 0.5 3.5 2 1 1 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 PFH32478.1 - 7.9e-05 22.4 3.1 0.0061 16.4 0.3 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 PFH32478.1 - 9.8e-05 21.7 0.9 9.8e-05 21.7 0.9 3.3 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.9 PFH32478.1 - 0.0012 19.1 0.0 0.038 14.3 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PFH32478.1 - 0.04 13.9 0.2 0.052 13.5 0.2 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand CTP_transf_like PF01467.26 PFH32479.1 - 5.6e-09 36.3 0.0 0.0003 21.0 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase-like RRM_1 PF00076.22 PFH32480.1 - 1.8e-18 66.1 0.0 1.4e-08 34.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 PFH32480.1 - 5.4e-06 26.4 0.1 0.0015 18.6 0.0 2.4 2 0 0 2 2 2 2 Limkain b1 Nup35_RRM_2 PF14605.6 PFH32480.1 - 0.00014 21.8 0.0 0.00053 19.9 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 PFH32480.1 - 0.00076 19.1 0.0 0.0046 16.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PFH32480.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pkinase PF00069.25 PFH32481.1 - 4.5e-80 268.8 0.0 7.2e-80 268.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32481.1 - 8.1e-42 143.3 0.1 3e-41 141.4 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.32 PFH32481.1 - 1e-27 93.6 8.2 1.7e-06 27.2 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PFH32481.1 - 8.7e-24 83.8 9.2 7.4e-12 45.5 1.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH32481.1 - 7.9e-22 75.3 5.5 2.1e-05 24.1 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PFH32481.1 - 1.2e-19 68.8 10.0 2.5e-06 26.7 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 PFH32481.1 - 7.5e-14 51.3 11.7 0.00018 21.3 1.8 4.4 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PFH32481.1 - 7.8e-07 29.4 4.6 0.002 18.4 0.5 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PFH32481.1 - 3.9e-06 26.7 6.3 0.00019 21.4 0.6 3.6 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.6 PFH32481.1 - 0.00018 21.0 0.0 0.00059 19.2 0.0 1.8 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PFH32481.1 - 0.00022 20.1 0.0 0.00031 19.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_10 PF14788.6 PFH32481.1 - 0.00055 19.7 6.1 0.32 10.9 0.6 3.6 3 1 1 4 4 4 2 EF hand APH PF01636.23 PFH32481.1 - 0.0018 18.3 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PFH32481.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DnaI_N PF07319.11 PFH32481.1 - 0.088 13.5 0.3 3.9 8.2 0.0 3.1 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus DAD PF02109.16 PFH32482.1 - 4.4e-17 62.4 1.9 4.7e-17 62.3 1.9 1.1 1 0 0 1 1 1 1 DAD family PT PF04886.12 PFH32483.1 - 9.8e-45 149.8 265.2 2.7e-07 30.0 16.5 22.0 22 0 0 22 22 22 15 PT repeat Lebercilin PF15619.6 PFH32483.1 - 1.1 8.9 4.7 3.6 7.2 4.7 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease UPF0300 PF08594.10 PFH32484.1 - 0.087 12.1 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) Rhodanese PF00581.20 PFH32485.1 - 4.9e-09 36.7 0.0 0.0095 16.4 0.1 4.0 3 1 0 3 3 3 3 Rhodanese-like domain HhH-GPD PF00730.25 PFH32486.1 - 9.8e-22 77.5 0.0 3e-21 75.9 0.0 1.9 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 PFH32486.1 - 1.3e-07 31.1 0.1 1.3e-06 27.9 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 PFH32486.1 - 0.041 14.5 0.0 0.66 10.6 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix domain zf-HC3 PF16827.5 PFH32487.1 - 0.0041 17.3 1.3 0.046 13.9 0.1 2.4 2 0 0 2 2 2 1 zinc-finger MRI PF15325.6 PFH32487.1 - 0.14 13.3 0.1 0.27 12.3 0.1 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection Pro_isomerase PF00160.21 PFH32488.1 - 3.6e-42 144.3 0.0 9.4e-42 143.0 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 PFH32488.1 - 4.9e-09 35.9 0.5 9.1e-09 35.1 0.5 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 PFH32488.1 - 3.3e-05 23.9 0.2 8.5e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 PFH32488.1 - 0.00058 19.6 1.0 0.28 11.0 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 PFH32488.1 - 0.016 15.3 0.0 0.13 12.4 0.0 2.3 1 1 1 2 2 2 0 U-box domain TPR_2 PF07719.17 PFH32490.1 - 4.1e-22 76.4 8.5 0.0027 17.7 0.0 8.0 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 PFH32490.1 - 4.9e-14 51.4 0.0 0.19 11.6 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 PFH32490.1 - 2.9e-13 49.4 25.6 0.0024 18.5 0.0 7.9 6 2 2 8 8 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 PFH32490.1 - 2.8e-10 40.7 7.2 6.5e-07 29.9 1.0 7.0 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 PFH32490.1 - 3.5e-10 39.3 0.0 0.13 12.5 0.0 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 PFH32490.1 - 6.6e-10 38.5 2.1 0.0059 16.3 0.0 4.9 4 1 1 5 5 5 3 TPR repeat TPR_7 PF13176.6 PFH32490.1 - 3.8e-08 32.8 2.0 0.38 10.9 0.1 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 PFH32490.1 - 1.9e-06 27.8 1.0 3 8.4 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 PFH32490.1 - 3.6e-06 27.2 16.3 0.0047 17.2 0.2 6.0 4 2 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 PFH32490.1 - 1e-05 25.9 5.4 0.37 11.3 0.3 4.7 3 1 3 6 6 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 PFH32490.1 - 0.00079 18.7 1.2 0.00079 18.7 1.2 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 PFH32490.1 - 0.0015 19.0 7.0 0.016 15.7 0.2 3.5 2 2 0 2 2 2 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 PFH32490.1 - 0.006 16.7 15.6 0.047 13.8 0.2 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat ChAPs PF09295.10 PFH32490.1 - 0.009 15.1 0.0 0.13 11.3 0.0 2.2 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 PFH32490.1 - 0.54 10.5 0.0 0.54 10.5 0.0 4.0 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 PFH32490.1 - 6.7 6.7 8.3 9.3 6.3 0.3 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH32490.1 - 9.3 7.1 10.6 1.7e+02 3.2 0.1 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.14 PFH32491.1 - 2e-48 165.1 0.1 2.7e-48 164.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PFH32491.1 - 1.6e-30 105.6 0.5 3.3e-29 101.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PFH32491.1 - 3e-12 46.9 0.6 4.2e-11 43.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PFH32491.1 - 6.9e-05 22.1 5.6 0.00013 21.2 5.6 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 PFH32491.1 - 0.00016 21.3 0.8 0.00028 20.5 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 PFH32491.1 - 0.00047 19.5 3.4 0.18 11.1 0.3 2.9 4 0 0 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 PFH32491.1 - 0.0011 18.9 0.7 0.087 12.7 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 PFH32491.1 - 0.0015 17.9 0.0 0.8 9.0 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 PFH32491.1 - 0.0027 16.9 4.8 0.0059 15.7 2.6 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 PFH32491.1 - 0.011 15.1 2.6 0.019 14.3 2.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 PFH32491.1 - 0.29 10.7 9.1 0.96 9.0 2.5 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase AP2 PF00847.20 PFH32492.1 - 5.1e-21 74.7 16.5 2.6e-10 40.3 0.5 3.6 3 0 0 3 3 3 3 AP2 domain ACDC PF14733.6 PFH32492.1 - 4.5e-09 36.5 0.4 6.8e-06 26.3 0.1 2.3 2 0 0 2 2 2 2 AP2-coincident C-terminal Chorein_N PF12624.7 PFH32493.1 - 3.4e-21 75.5 0.0 6.7e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 PFH32493.1 - 5.1e-14 52.7 0.0 1.8e-12 47.6 0.0 2.7 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 PFH32493.1 - 3.2e-11 43.3 0.0 9.4e-11 41.8 0.0 1.8 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 PFH32493.1 - 5.1e-05 22.8 0.0 0.00024 20.6 0.0 1.9 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 GST_N_3 PF13417.6 PFH32494.1 - 9.3e-20 70.8 0.3 8.8e-13 48.5 0.0 3.0 2 1 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PFH32494.1 - 1.1e-06 28.8 0.0 1.4e-05 25.3 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 PFH32494.1 - 0.0033 17.6 0.3 0.021 15.0 0.5 2.1 2 0 0 2 2 2 1 Glutaredoxin zf-CHY PF05495.12 PFH32495.1 - 2.5e-13 50.3 15.3 9.9e-11 42.0 10.0 3.3 2 1 1 3 3 3 2 CHY zinc finger Myb_DNA-binding PF00249.31 PFH32495.1 - 3.3e-05 24.0 0.9 3.3e-05 24.0 0.9 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf_CCCH_4 PF18345.1 PFH32495.1 - 0.00034 20.6 1.3 0.00034 20.6 1.3 2.2 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 PFH32495.1 - 0.031 15.0 0.0 0.031 15.0 0.0 2.1 2 0 0 2 2 2 0 Torus domain Myb_DNA-bind_6 PF13921.6 PFH32495.1 - 0.14 12.4 0.4 0.3 11.4 0.4 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-CCCH_4 PF18044.1 PFH32495.1 - 0.47 10.3 6.3 0.064 13.1 1.4 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger Fasciclin PF02469.22 PFH32496.1 - 1.2e-08 35.3 0.0 2.3e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Fasciclin domain DUF4201 PF13870.6 PFH32498.1 - 1e-26 93.8 21.6 1.2e-26 93.5 21.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF2944 PF11161.8 PFH32498.1 - 0.15 12.0 2.4 0.27 11.1 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Preseq_ALAS PF09029.10 PFH32498.1 - 0.15 12.5 2.7 0.29 11.6 2.7 1.4 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence ALMT PF11744.8 PFH32498.1 - 0.95 8.2 8.5 1.2 7.9 8.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4527 PF15030.6 PFH32498.1 - 2.7 7.4 18.0 0.043 13.2 10.6 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4527) HisKA PF00512.25 PFH32498.1 - 4.1 7.5 8.7 1.6 8.9 1.0 3.1 2 2 1 3 3 3 0 His Kinase A (phospho-acceptor) domain VIT1 PF01988.19 PFH32498.1 - 7.3 6.4 8.0 0.52 10.1 0.1 2.1 2 0 0 2 2 2 0 VIT family DEAD PF00270.29 PFH32499.1 - 1.6e-16 60.5 0.0 3.3e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH32499.1 - 1.7e-14 54.1 0.0 2.9e-13 50.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 PFH32499.1 - 5.7e-14 52.6 0.2 1.3e-13 51.4 0.2 1.7 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 PFH32499.1 - 1.9e-05 24.4 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 PFH32499.1 - 0.0064 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1764 PF08576.10 PFH32501.1 - 1.9e-23 83.3 2.0 1.9e-23 83.3 2.0 2.8 2 2 1 3 3 3 1 Eukaryotic protein of unknown function (DUF1764) CDC73_C PF05179.14 PFH32502.1 - 6.9e-37 126.6 0.0 1e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC45 PF02724.14 PFH32502.1 - 0.0075 14.6 0.0 0.01 14.2 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein IspD PF01128.19 PFH32504.1 - 1e-23 84.3 1.2 2.8e-16 59.9 0.2 4.0 4 1 1 5 5 5 3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YscW PF09619.10 PFH32505.1 - 0.0044 17.3 0.0 0.0059 17.0 0.0 1.3 1 0 0 1 1 1 1 Type III secretion system lipoprotein chaperone (YscW) Med7 PF05983.11 PFH32506.1 - 8.2e-18 65.2 0.0 1.1e-17 64.7 0.0 1.2 1 0 0 1 1 1 1 MED7 protein RNA_pol_Rpb1_5 PF04998.17 PFH32507.1 - 3.4e-87 292.3 0.0 4.7e-87 291.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 PFH32507.1 - 1.8e-75 254.2 0.1 2.9e-75 253.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 PFH32507.1 - 5e-71 238.3 0.0 1.1e-70 237.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 PFH32507.1 - 1.8e-34 119.0 0.0 3.7e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 PFH32507.1 - 5.5e-30 103.5 0.0 1.5e-29 102.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF3964 PF13107.6 PFH32509.1 - 0.23 11.8 0.0 0.41 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) SMC_N PF02463.19 PFH32510.1 - 5.5e-40 137.1 0.0 1.6e-39 135.7 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 PFH32510.1 - 5.1e-14 52.8 2.4 2e-10 40.9 0.0 4.7 5 0 0 5 5 5 1 AAA ATPase domain AAA_23 PF13476.6 PFH32510.1 - 4.1e-13 50.3 14.3 4.1e-13 50.3 14.3 6.8 2 2 1 3 3 3 1 AAA domain SMC_hinge PF06470.13 PFH32510.1 - 3e-11 43.6 0.0 3.4e-10 40.3 0.0 2.9 1 1 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 PFH32510.1 - 1.8e-10 41.1 0.1 8.2e-05 22.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PFH32510.1 - 0.0083 15.8 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 PFH32510.1 - 0.073 13.5 0.0 5 7.5 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PFH32510.1 - 7 7.2 19.3 1.7 9.2 0.0 5.0 5 1 0 5 5 5 0 ABC transporter Myb_DNA-binding PF00249.31 PFH32511.1 - 1.5e-10 41.1 0.4 2.8e-10 40.2 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PFH32511.1 - 4.3e-06 26.9 0.1 9.8e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PFH32511.1 - 0.0075 16.1 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Hydrolase_4 PF12146.8 PFH32512.1 - 2.3e-24 86.0 2.2 5.7e-21 74.9 0.7 3.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PFH32512.1 - 2.6e-07 31.5 0.1 4.8e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PFH32512.1 - 0.0019 17.9 0.0 0.0062 16.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold UPF0227 PF05728.12 PFH32512.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) EOS1 PF12326.8 PFH32512.1 - 0.14 12.1 0.7 0.26 11.2 0.7 1.3 1 0 0 1 1 1 0 N-glycosylation protein CDC45 PF02724.14 PFH32512.1 - 0.7 8.1 6.5 1.1 7.5 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA_6 PF12774.7 PFH32513.1 - 1.7e-144 480.8 0.0 1.4e-142 474.5 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PFH32513.1 - 1.4e-113 380.0 8.2 1.4e-113 380.0 8.2 4.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PFH32513.1 - 1.8e-86 290.2 0.9 3.7e-85 285.9 0.0 2.9 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 PFH32513.1 - 3.3e-85 285.5 0.0 1.2e-84 283.7 0.0 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 PFH32513.1 - 6e-76 254.4 4.3 6e-76 254.4 4.3 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 PFH32513.1 - 8.5e-51 172.0 0.1 1.8e-50 171.0 0.1 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 PFH32513.1 - 1.8e-50 171.0 0.0 3.4e-45 153.8 0.0 4.5 4 0 0 4 4 4 3 P-loop containing dynein motor region MT PF12777.7 PFH32513.1 - 1.7e-42 145.7 16.4 1.7e-42 145.7 16.4 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PFH32513.1 - 8.8e-39 132.3 0.0 4.4e-38 130.0 0.0 2.4 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 PFH32513.1 - 1.3e-22 79.8 1.7 1.6e-20 73.2 0.0 3.5 3 0 0 3 3 3 1 AAA+ lid domain AAA_5 PF07728.14 PFH32513.1 - 3.4e-22 78.9 0.0 6.9e-07 29.3 0.0 5.5 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 PFH32513.1 - 7.7e-22 77.8 0.0 3.1e-20 72.6 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 PFH32513.1 - 9.3e-07 29.3 0.3 0.36 11.3 0.0 4.8 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 PFH32513.1 - 1.3e-05 25.8 0.2 0.31 11.6 0.0 4.8 5 0 0 5 5 4 1 AAA domain AAA_22 PF13401.6 PFH32513.1 - 0.00024 21.4 15.3 0.11 12.8 0.0 6.2 7 0 0 7 7 5 2 AAA domain Bac_luciferase PF00296.20 PFH32513.1 - 0.0075 15.7 2.0 0.082 12.3 0.3 2.9 3 0 0 3 3 3 1 Luciferase-like monooxygenase AAA_33 PF13671.6 PFH32513.1 - 0.014 15.5 0.3 16 5.6 0.0 4.2 3 0 0 3 3 3 0 AAA domain DHC_N1 PF08385.12 PFH32514.1 - 5.5e-177 589.8 15.6 6.8e-177 589.5 15.6 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 CCDC106 PF15794.5 PFH32514.1 - 0.0032 17.2 0.1 0.0073 16.0 0.1 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 DUF3583 PF12126.8 PFH32514.1 - 0.028 13.9 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) AAA_assoc_C PF09821.9 PFH32514.1 - 0.062 13.8 0.1 0.26 11.8 0.1 2.1 1 0 0 1 1 1 0 C-terminal AAA-associated domain Baculo_PEP_C PF04513.12 PFH32514.1 - 1.7 8.7 4.6 2.6 8.1 0.1 3.2 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2353 PF09789.9 PFH32515.1 - 0.0043 16.5 2.2 0.0066 15.8 2.2 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) CREPT PF16566.5 PFH32515.1 - 0.037 14.2 0.8 0.07 13.3 0.8 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour RsgA_GTPase PF03193.16 PFH32515.1 - 0.77 9.6 3.0 0.65 9.9 0.3 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF4407 PF14362.6 PFH32515.1 - 8.6 5.6 6.2 1.7 7.9 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) zf-U1 PF06220.12 PFH32516.1 - 2.5e-18 65.6 2.3 3.5e-18 65.1 2.3 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.7 PFH32516.1 - 6.3 7.3 5.1 61 4.2 5.1 2.1 1 1 0 1 1 1 0 Zinc-finger of C2H2 type COX6B PF02297.17 PFH32517.1 - 0.008 16.4 7.8 0.018 15.2 7.8 1.6 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Hid1 PF12722.7 PFH32518.1 - 0.64 8.1 1.3 1.1 7.3 1.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec34 PF04136.15 PFH32519.1 - 3.2e-16 59.5 0.0 6.1e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 Sec34-like family Sigma70_ner PF04546.13 PFH32519.1 - 0.0006 19.8 0.0 0.013 15.4 0.0 2.7 2 0 0 2 2 2 1 Sigma-70, non-essential region Nup54_C PF18437.1 PFH32519.1 - 0.19 11.6 0.7 0.4 10.6 0.7 1.5 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain SAS-6_N PF16531.5 PFH32520.1 - 9.6e-21 74.2 0.0 2.2e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal DUF4936 PF16290.5 PFH32520.1 - 0.094 13.4 0.1 0.094 13.4 0.1 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4936) Taxilin PF09728.9 PFH32520.1 - 6.9 5.7 63.7 15 4.6 63.4 1.7 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Coilin_N PF15862.5 PFH32522.1 - 0.0001 22.1 12.8 0.00012 21.9 12.8 1.2 1 0 0 1 1 1 1 Coilin N-terminus Presenilin PF01080.17 PFH32522.1 - 0.019 13.7 9.1 0.021 13.6 9.1 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 PFH32522.1 - 0.025 13.8 2.8 0.026 13.7 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1980 PF09323.10 PFH32522.1 - 0.038 13.9 0.4 0.049 13.5 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PPL5 PF18168.1 PFH32522.1 - 0.053 12.8 7.3 0.048 13.0 7.3 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Connexin PF00029.19 PFH32522.1 - 0.13 12.0 8.9 0.15 11.8 8.9 1.3 1 0 0 1 1 1 0 Connexin V_ATPase_I PF01496.19 PFH32522.1 - 0.16 9.8 7.9 0.17 9.8 7.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 PFH32522.1 - 0.27 11.2 5.4 0.3 11.1 5.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4228 PF14009.6 PFH32522.1 - 0.41 11.0 10.2 0.44 10.9 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF789 PF05623.12 PFH32522.1 - 0.52 9.9 5.3 0.6 9.8 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF789) CBP_BcsG PF11658.8 PFH32522.1 - 0.67 8.3 3.4 0.72 8.2 3.4 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG CLN3 PF02487.17 PFH32522.1 - 0.71 8.9 4.9 0.68 8.9 4.9 1.1 1 0 0 1 1 1 0 CLN3 protein SID-1_RNA_chan PF13965.6 PFH32522.1 - 0.71 8.2 1.7 0.73 8.2 1.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 PFH32522.1 - 0.88 8.4 3.8 0.97 8.3 3.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF913 PF06025.12 PFH32522.1 - 1.2 8.1 7.0 1.1 8.1 7.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 PFH32522.1 - 1.5 8.9 9.5 1.7 8.8 9.5 1.1 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.6 PFH32522.1 - 1.6 8.4 15.8 1.7 8.4 15.8 1.0 1 0 0 1 1 1 0 AAA domain DUF1682 PF07946.14 PFH32522.1 - 1.6 7.8 28.4 1.9 7.6 28.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF2828 PF11443.8 PFH32522.1 - 3.1 5.8 17.2 3.1 5.8 17.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CSG2 PF16965.5 PFH32522.1 - 3.1 6.7 3.5 2.9 6.7 3.5 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator O-antigen_lig PF13425.6 PFH32522.1 - 5.3 5.7 5.0 5.5 5.7 5.0 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein BORG_CEP PF14957.6 PFH32522.1 - 5.5 8.2 10.4 6.3 8.0 10.4 1.1 1 0 0 1 1 1 0 Cdc42 effector NARP1 PF12569.8 PFH32522.1 - 9.6 5.0 28.3 10 4.9 28.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Silic_transp PF03842.13 PFH32522.1 - 9.9 4.3 6.2 11 4.2 6.2 1.2 1 0 0 1 1 1 0 Silicon transporter RPN2_C PF18004.1 PFH32522.1 - 9.9 6.1 25.7 13 5.7 25.7 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain V_ATPase_I PF01496.19 PFH32523.1 - 0.19 9.6 0.0 0.2 9.6 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 PFH32523.1 - 0.2 10.8 1.0 0.22 10.7 1.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sperm_Ag_HE2 PF05324.13 PFH32523.1 - 3.9 8.0 5.9 1.2e+02 3.2 5.9 2.1 1 1 0 1 1 1 0 Sperm antigen HE2 Bromodomain PF00439.25 PFH32524.1 - 8.5e-19 67.4 0.3 1.4e-18 66.7 0.3 1.3 1 0 0 1 1 1 1 Bromodomain ICMT PF04140.14 PFH32525.1 - 1.2e-20 73.7 0.5 2.7e-20 72.6 0.1 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 PFH32525.1 - 1.1e-08 35.4 2.5 2.7e-08 34.2 2.5 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase NnrU PF07298.11 PFH32525.1 - 0.0056 16.2 1.0 0.013 15.0 1.0 1.6 1 0 0 1 1 1 1 NnrU protein Pkinase PF00069.25 PFH32526.1 - 6.2e-63 212.6 0.0 5.4e-34 117.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32526.1 - 5.1e-29 101.3 0.0 8e-17 61.4 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 PFH32526.1 - 0.00063 19.2 0.4 0.0011 18.3 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PFH32526.1 - 0.043 13.1 1.1 5.2 6.3 0.0 2.7 3 0 0 3 3 3 0 Kinase-like P22_portal PF16510.5 PFH32526.1 - 0.77 8.3 2.4 1.1 7.7 2.4 1.1 1 0 0 1 1 1 0 Phage P22-like portal protein DUF515 PF04415.12 PFH32527.1 - 0.18 10.1 0.2 0.28 9.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) BSD PF03909.17 PFH32528.1 - 9.6e-07 28.7 0.5 1.8e-06 27.8 0.5 1.4 1 0 0 1 1 1 1 BSD domain PsbQ PF05757.11 PFH32528.1 - 0.005 16.6 3.2 0.005 16.6 3.2 2.0 2 0 0 2 2 2 1 Oxygen evolving enhancer protein 3 (PsbQ) Alpha-2-MRAP_N PF06400.11 PFH32528.1 - 0.081 12.9 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, N-terminal domain Angiomotin_C PF12240.8 PFH32529.1 - 0.025 14.1 0.1 0.06 12.9 0.1 1.6 1 0 0 1 1 1 0 Angiomotin C terminal SseB_C PF14581.6 PFH32529.1 - 0.096 12.8 0.4 0.26 11.4 0.4 1.7 1 0 0 1 1 1 0 SseB protein C-terminal domain Ins_allergen_rp PF06757.13 PFH32530.1 - 3.2 7.7 5.1 0.83 9.6 0.2 2.4 3 0 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification TruB_N PF01509.18 PFH32533.1 - 2.9e-41 141.3 0.1 9.4e-37 126.7 0.1 2.1 2 0 0 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 PFH32533.1 - 2e-06 27.8 0.1 4e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Choline_kinase PF01633.20 PFH32535.1 - 1.9e-40 138.7 0.0 2.7e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 PFH32535.1 - 3.7e-15 56.5 1.0 3.7e-15 56.5 1.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 PFH32535.1 - 0.00073 18.9 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Misat_Tub_SegII PF10644.9 PFH32535.1 - 0.044 14.1 0.0 0.098 13.0 0.0 1.6 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain Fructosamin_kin PF03881.14 PFH32535.1 - 0.063 12.5 0.0 0.48 9.6 0.0 2.0 2 0 0 2 2 2 0 Fructosamine kinase GHMP_kinases_N PF00288.26 PFH32537.1 - 0.00042 20.5 2.1 0.00042 20.5 2.1 2.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain Nucleoporin_FG PF13634.6 PFH32538.1 - 1.5e-27 96.3 184.4 1e-07 32.7 34.1 7.1 2 2 5 7 7 7 7 Nucleoporin FG repeat region Prominin PF05478.11 PFH32538.1 - 0.59 8.0 5.4 0.04 11.9 0.4 1.5 2 0 0 2 2 2 0 Prominin Laminin_II PF06009.12 PFH32538.1 - 8.4 6.4 10.2 35 4.4 0.0 3.1 2 1 1 3 3 3 0 Laminin Domain II FeS_assembly_P PF01883.19 PFH32541.1 - 2e-06 27.8 0.0 0.026 14.7 0.0 2.6 2 0 0 2 2 2 2 Iron-sulfur cluster assembly protein RRM_1 PF00076.22 PFH32542.1 - 1.3e-14 53.7 0.2 3.2e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PFH32542.1 - 0.00027 20.5 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 PFH32542.1 - 0.077 13.2 0.2 0.34 11.1 0.0 1.9 1 1 1 2 2 2 0 RRM-like domain RNase_PH PF01138.21 PFH32543.1 - 6.6e-10 39.6 0.0 1.3e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 AP2 PF00847.20 PFH32544.1 - 0.00086 19.5 1.2 0.0014 18.8 1.2 1.4 1 0 0 1 1 1 1 AP2 domain DUF2046 PF09755.9 PFH32545.1 - 0.032 13.5 1.2 0.053 12.8 1.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Miff PF05644.11 PFH32545.1 - 0.12 12.0 1.3 0.28 10.8 1.3 1.6 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff GCD14 PF08704.10 PFH32546.1 - 4.1e-65 219.9 0.0 3.4e-40 138.3 0.0 3.1 3 0 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 PFH32546.1 - 0.00054 19.8 0.0 0.05 13.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain PCMT PF01135.19 PFH32546.1 - 0.00055 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 PFH32546.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Sec20 PF03908.13 PFH32547.1 - 0.00029 20.7 0.9 0.00066 19.6 0.9 1.6 1 0 0 1 1 1 1 Sec20 V-SNARE_C PF12352.8 PFH32547.1 - 0.00036 20.8 1.1 0.00036 20.8 1.1 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Baculo_PEP_C PF04513.12 PFH32547.1 - 0.36 10.8 4.7 0.24 11.4 0.5 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-SNARE PF05008.15 PFH32547.1 - 0.88 10.0 9.9 0.26 11.7 2.7 2.8 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus MCPsignal PF00015.21 PFH32547.1 - 1.8 8.4 9.1 4.6 7.0 2.4 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PseudoU_synth_2 PF00849.22 PFH32549.1 - 5.1e-18 65.7 0.0 8.9e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase USP7_ICP0_bdg PF12436.8 PFH32549.1 - 0.092 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 B12D PF06522.11 PFH32550.1 - 0.00076 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RimM PF01782.18 PFH32551.1 - 4.6e-18 65.2 0.2 1e-17 64.1 0.2 1.6 1 0 0 1 1 1 1 RimM N-terminal domain Pro_Al_protease PF02983.14 PFH32551.1 - 2 8.6 5.5 0.67 10.1 0.1 2.9 3 0 0 3 3 3 0 Alpha-lytic protease prodomain APG12 PF04110.13 PFH32552.1 - 4e-19 68.8 0.0 5.7e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 LSM PF01423.22 PFH32556.1 - 3.6e-19 68.2 0.1 4.4e-19 67.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain PseudoU_synth_2 PF00849.22 PFH32557.1 - 3.5e-23 82.5 2.5 6.6e-12 45.8 0.9 2.5 2 1 0 2 2 2 2 RNA pseudouridylate synthase PGBA_C PF15437.6 PFH32557.1 - 0.13 12.7 11.3 0.27 11.6 11.3 1.5 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Gemini_coat PF00844.18 PFH32557.1 - 1 8.7 4.8 2.2 7.7 4.8 1.5 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family NAD_binding_1 PF00175.21 PFH32558.1 - 1.3e-17 64.4 0.0 2.2e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PFH32558.1 - 0.00011 22.5 0.0 0.0018 18.6 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain RHH_4 PF13467.6 PFH32558.1 - 0.17 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain AP2 PF00847.20 PFH32560.1 - 1.1e-10 41.5 0.8 2.4e-10 40.5 0.8 1.5 1 0 0 1 1 1 1 AP2 domain ACDC PF14733.6 PFH32560.1 - 1.8e-08 34.6 0.0 4.3e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 AP2-coincident C-terminal RRM_2 PF04059.12 PFH32561.1 - 1.4e-30 105.4 0.4 2e-30 104.9 0.4 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 PFH32561.1 - 0.092 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPI2 PF06432.11 PFH32562.1 - 4.9e-72 242.7 11.6 5.6e-72 242.5 11.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Ribosomal_L22 PF00237.19 PFH32563.1 - 2.8e-40 136.7 0.2 3.8e-40 136.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Na_H_Exchanger PF00999.21 PFH32564.1 - 8.9e-50 169.6 37.7 1.3e-49 169.0 37.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Cas_Csn2 PF09711.10 PFH32565.1 - 0.18 11.4 2.8 0.097 12.3 0.4 1.7 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csn2) YebO PF13974.6 PFH32565.1 - 1.5 9.0 8.2 0.065 13.3 1.4 2.3 3 0 0 3 3 3 0 YebO-like protein TMPIT PF07851.13 PFH32565.1 - 3.5 6.8 8.2 0.14 11.4 2.2 1.6 2 0 0 2 2 2 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 PFH32565.1 - 7.4 6.7 21.0 3.8 7.6 7.5 2.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein PK PF00224.21 PFH32566.1 - 2.2e-94 316.2 0.0 5.3e-49 167.0 0.2 2.1 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 PFH32566.1 - 1.3e-20 73.8 0.3 4.7e-19 68.7 0.2 2.7 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 PFH32566.1 - 0.016 14.4 0.2 0.069 12.3 0.0 2.0 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family VTC PF09359.10 PFH32567.1 - 1.8e-110 368.7 0.0 3e-110 368.0 0.0 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 PFH32567.1 - 7.5e-09 35.9 2.3 2e-08 34.6 2.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF3306 PF11748.8 PFH32567.1 - 0.0025 18.7 4.9 0.0025 18.7 4.9 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF3306) CLPTM1 PF05602.12 PFH32569.1 - 2.1e-40 139.1 7.7 2.1e-39 135.8 7.7 2.5 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) UPF0242 PF06785.11 PFH32569.1 - 7.1 6.7 11.6 2.5 8.2 1.6 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AP2 PF00847.20 PFH32571.1 - 3.5e-14 52.7 6.7 2e-06 27.9 0.4 2.5 2 0 0 2 2 2 2 AP2 domain AAA PF00004.29 PFH32572.1 - 1.3e-38 132.4 0.0 2.3e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PFH32572.1 - 2.6e-12 46.4 0.3 6.6e-12 45.0 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PFH32572.1 - 0.00036 20.8 0.1 0.015 15.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 PFH32572.1 - 0.00036 19.9 0.1 0.00076 18.8 0.1 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain baeRF_family3 PF18845.1 PFH32572.1 - 0.0006 20.1 0.7 0.0044 17.3 0.0 2.3 1 1 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 3 AAA_2 PF07724.14 PFH32572.1 - 0.0013 18.8 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PFH32572.1 - 0.0015 18.5 0.1 0.0041 17.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PFH32572.1 - 0.0041 17.5 10.9 0.0042 17.5 0.1 3.8 2 2 1 4 4 4 1 AAA ATPase domain RuvB_N PF05496.12 PFH32572.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.6 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 PFH32572.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CPT PF07931.12 PFH32572.1 - 0.016 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.21 PFH32572.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 PFH32572.1 - 0.021 14.5 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 PFH32572.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 PFH32572.1 - 0.024 14.8 0.0 0.082 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PFH32572.1 - 0.032 14.8 0.0 0.085 13.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 PFH32572.1 - 0.032 14.1 0.1 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Cytidylate_kin PF02224.18 PFH32572.1 - 0.13 11.9 1.4 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_7 PF12775.7 PFH32572.1 - 0.21 11.1 0.0 0.87 9.1 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 PFH32572.1 - 0.22 11.4 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Ten1_2 PF15490.6 PFH32573.1 - 0.00044 19.9 0.8 0.00093 18.9 0.3 1.8 2 0 0 2 2 2 1 Telomere-capping, CST complex subunit CDC45 PF02724.14 PFH32573.1 - 0.8 7.9 4.7 1.2 7.4 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SPX PF03105.19 PFH32573.1 - 1.7 8.5 18.0 0.6 10.0 11.5 2.0 2 0 0 2 2 2 0 SPX domain Longin PF13774.6 PFH32574.1 - 1.7e-08 34.4 0.0 3.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 PFH32574.1 - 9.1e-06 25.4 1.3 1.3e-05 24.9 1.3 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF4259 PF14078.6 PFH32574.1 - 0.027 15.2 0.2 0.45 11.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) zf-B_box PF00643.24 PFH32575.1 - 1.3e-06 28.4 18.8 0.00013 22.0 4.3 4.4 5 1 0 5 5 5 2 B-box zinc finger CEBP_ZZ PF16366.5 PFH32575.1 - 0.0016 18.6 5.6 0.0016 18.6 5.6 3.1 4 0 0 4 4 4 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-UBR PF02207.20 PFH32575.1 - 0.01 15.9 3.5 0.01 15.9 3.5 3.4 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) zf-RING_5 PF14634.6 PFH32575.1 - 0.013 15.5 1.1 0.013 15.5 1.1 3.9 4 0 0 4 4 4 0 zinc-RING finger domain INTS5_N PF14837.6 PFH32575.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus AAA_32 PF13654.6 PFH32575.1 - 0.11 11.3 3.7 0.2 10.4 3.7 1.3 1 0 0 1 1 1 0 AAA domain TRAPP PF04051.16 PFH32576.1 - 1e-32 112.9 0.1 1.2e-32 112.6 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CTP_synth_N PF06418.14 PFH32577.1 - 1.4e-119 398.3 0.1 1.9e-119 397.8 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 PFH32577.1 - 1.8e-50 171.4 0.0 2.8e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 PFH32577.1 - 4.7e-05 23.3 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 PFH32577.1 - 0.00082 19.4 0.0 0.0012 18.9 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 PFH32577.1 - 0.0051 15.8 0.4 0.0087 15.1 0.4 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB F-box-like PF12937.7 PFH32579.1 - 8.8e-09 35.1 4.4 4.6e-08 32.8 4.4 2.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PFH32579.1 - 6.1e-07 29.2 2.7 1.9e-06 27.6 2.7 1.9 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 PFH32579.1 - 0.02 14.5 0.2 0.08 12.5 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain Elongin_A PF06881.11 PFH32579.1 - 0.028 14.9 0.1 0.064 13.8 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box_4 PF15966.5 PFH32579.1 - 0.038 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 F-box Methyltransf_15 PF09445.10 PFH32583.1 - 3.2e-23 82.1 0.0 3.6e-22 78.7 0.0 2.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MIF4G PF02854.19 PFH32584.1 - 1.6e-30 106.3 5.1 2.1e-30 106.0 5.1 1.1 1 0 0 1 1 1 1 MIF4G domain Cyclin_C PF02984.19 PFH32589.1 - 0.011 15.9 0.0 0.063 13.4 0.0 2.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain Proteasome PF00227.26 PFH32590.1 - 7e-37 126.8 0.0 7.8e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CRAL_TRIO PF00650.20 PFH32591.1 - 1.1e-09 38.2 0.0 1.5e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Melibiase_2 PF16499.5 PFH32592.1 - 2.6e-31 108.9 0.0 4.3e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 PFH32592.1 - 0.00013 21.1 0.0 0.0002 20.4 0.0 1.2 1 0 0 1 1 1 1 Melibiase Sulf_transp PF04143.14 PFH32592.1 - 0.26 10.8 1.5 5.2 6.5 0.4 2.1 2 0 0 2 2 2 0 Sulphur transport ATF7IP_BD PF16788.5 PFH32592.1 - 1.1 9.3 7.9 1.8 8.6 7.9 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain ALMT PF11744.8 PFH32592.1 - 1.3 7.7 6.6 2.3 7.0 6.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter TerD PF02342.18 PFH32593.1 - 0.0008 18.9 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 TerD domain CysG_dimeriser PF10414.9 PFH32593.1 - 0.006 16.3 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 Sirohaem synthase dimerisation region UBA PF00627.31 PFH32594.1 - 0.014 15.3 0.3 0.049 13.5 0.0 2.1 2 0 0 2 2 2 0 UBA/TS-N domain U79_P34 PF03064.16 PFH32594.1 - 4.2 6.7 6.3 15 4.9 0.0 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DUF1664 PF07889.12 PFH32595.1 - 0.097 12.7 0.5 5.2 7.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PIN_4 PF13638.6 PFH32595.1 - 0.16 12.2 2.0 0.18 12.1 0.2 1.9 2 0 0 2 2 2 0 PIN domain CLZ PF16526.5 PFH32595.1 - 0.33 11.3 4.3 0.92 9.9 0.0 2.9 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3450 PF11932.8 PFH32595.1 - 1.1 8.5 8.1 0.18 11.1 0.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Lebercilin PF15619.6 PFH32595.1 - 2.7 7.6 14.0 0.73 9.5 3.0 2.6 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Rab5-bind PF09311.11 PFH32595.1 - 2.8 7.2 18.2 0.67 9.3 3.2 3.3 2 1 1 3 3 3 0 Rabaptin-like protein XhlA PF10779.9 PFH32595.1 - 9.1 6.6 7.8 0.68 10.2 0.5 2.7 3 0 0 3 3 3 0 Haemolysin XhlA TPR_12 PF13424.6 PFH32596.1 - 6.7e-08 32.7 11.9 0.002 18.4 2.1 3.6 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PFH32596.1 - 1.3e-06 28.0 6.9 0.024 14.7 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PFH32596.1 - 2.1e-06 27.3 2.1 0.015 15.1 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 PFH32596.1 - 6.6e-05 22.7 7.9 1.9 8.7 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 PFH32596.1 - 0.19 12.0 0.1 4.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 PFH32596.1 - 1.3 9.0 11.4 29 4.7 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 PFH32597.1 - 4.4e-09 36.0 0.0 8.1e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_16 PF10294.9 PFH32598.1 - 0.072 12.8 0.0 17 5.1 0.0 3.3 3 0 0 3 3 3 0 Lysine methyltransferase FAST_1 PF06743.15 PFH32600.1 - 0.052 13.5 0.3 0.61 10.1 0.0 2.5 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Complex1_LYR PF05347.15 PFH32601.1 - 2.4e-07 30.7 1.1 3.2e-07 30.3 1.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 PFH32601.1 - 0.062 14.1 0.2 0.08 13.7 0.2 1.1 1 0 0 1 1 1 0 Complex1_LYR-like Seryl_tRNA_N PF02403.22 PFH32602.1 - 0.046 14.0 0.2 0.15 12.3 0.2 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain GreA_GreB_N PF03449.15 PFH32602.1 - 6 7.1 5.3 2.4 8.4 0.3 2.9 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal Metallophos PF00149.28 PFH32604.1 - 5.9e-12 46.5 0.0 8.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 PFH32604.1 - 0.049 11.9 0.1 3.5 5.8 0.1 2.1 2 0 0 2 2 2 0 Firmicute fructose-1,6-bisphosphatase DUF4392 PF14336.6 PFH32605.1 - 1.8e-69 234.5 0.0 2e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) CFAP91 PF14738.6 PFH32606.1 - 4.7e-10 39.7 8.0 4.7e-10 39.7 8.0 3.1 2 2 0 2 2 2 1 Cilia- and flagella-associated protein 91 DUF1759 PF03564.15 PFH32606.1 - 0.097 12.6 1.1 0.43 10.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) MitMem_reg PF13012.6 PFH32606.1 - 0.22 12.0 1.7 0.63 10.5 0.2 2.5 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function T2SSF PF00482.23 PFH32606.1 - 0.68 9.9 5.6 1.2 9.1 1.1 3.2 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F HTH_37 PF13744.6 PFH32606.1 - 0.84 9.6 7.0 0.096 12.7 1.4 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain ThiS PF02597.20 PFH32606.1 - 2.8 8.7 4.7 2.8 8.7 0.6 3.0 3 0 0 3 3 3 0 ThiS family Snapin_Pallidin PF14712.6 PFH32606.1 - 2.8 8.4 12.5 0.66 10.4 0.9 4.0 4 1 0 4 4 4 0 Snapin/Pallidin POP1 PF06978.11 PFH32607.1 - 2.9e-22 79.7 33.8 5.4e-16 59.2 7.3 4.1 3 1 1 4 4 4 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 PFH32607.1 - 4.5e-21 75.0 0.0 2.2e-20 72.8 0.0 2.3 2 0 0 2 2 2 1 POPLD (NUC188) domain DUF676 PF05057.14 PFH32608.1 - 2.8e-43 148.0 0.0 4.1e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 PFH32608.1 - 6.5e-06 26.6 0.0 2.8e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Protein FAM135 Palm_thioest PF02089.15 PFH32608.1 - 8.5e-06 25.8 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 PFH32608.1 - 0.05 13.3 0.1 0.2 11.3 0.1 1.8 1 1 0 1 1 1 0 PGAP1-like protein zf-RING_2 PF13639.6 PFH32609.1 - 9.9e-12 45.0 3.1 3.1e-11 43.4 3.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PFH32609.1 - 6.4e-10 38.7 3.8 1.3e-09 37.7 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PFH32609.1 - 1.3e-08 34.4 1.2 3.9e-08 32.9 1.2 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 PFH32609.1 - 9.1e-08 32.3 3.9 2.9e-07 30.6 3.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PFH32609.1 - 2.9e-07 30.4 0.2 1.3e-06 28.3 0.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PFH32609.1 - 1.5e-06 28.0 2.4 1.5e-06 28.0 2.4 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH32609.1 - 7.2e-06 25.9 1.9 7.2e-06 25.9 1.9 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PFH32609.1 - 0.00032 20.5 5.6 0.00082 19.2 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PFH32609.1 - 0.00069 19.6 2.6 0.002 18.1 2.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 PFH32609.1 - 0.047 13.8 3.3 0.18 12.0 3.3 2.0 1 0 0 1 1 1 0 RING-variant domain FOXP-CC PF16159.5 PFH32609.1 - 0.088 13.4 0.2 0.24 12.0 0.2 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-RING_4 PF14570.6 PFH32609.1 - 0.09 12.6 4.1 0.22 11.3 4.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 PFH32609.1 - 0.17 11.8 5.5 0.38 10.7 5.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 PFH32609.1 - 0.2 11.6 2.8 0.56 10.1 2.8 1.8 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 PFH32609.1 - 0.62 9.7 10.2 0.067 12.8 5.3 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 PFH32609.1 - 6.7 7.0 7.0 75 3.6 7.0 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain DHR10 PF18595.1 PFH32609.1 - 8.9 6.4 10.4 1 9.4 1.6 2.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Hydrolase_4 PF12146.8 PFH32610.1 - 8.7e-15 54.6 0.0 9.9e-10 38.1 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PFH32610.1 - 1.2e-10 41.5 0.0 3.9e-06 26.7 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PFH32610.1 - 5.4e-08 33.7 1.1 1.2e-07 32.6 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 PFH32610.1 - 5.1e-07 29.7 0.1 0.00033 20.6 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 PFH32610.1 - 4.3e-06 25.6 0.2 0.14 10.9 0.1 3.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 PFH32610.1 - 6.2e-06 26.2 1.6 1.6e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PFH32610.1 - 0.00011 21.8 0.0 0.00025 20.6 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 PFH32610.1 - 0.0075 15.9 0.0 1.7 8.2 0.0 3.0 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 PFH32610.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 PFH32610.1 - 0.062 13.2 0.0 5.5 6.8 0.0 2.4 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIDHydrolase PF10230.9 PFH32610.1 - 0.067 12.7 0.0 0.36 10.3 0.0 1.9 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Ank_2 PF12796.7 PFH32612.1 - 2.4e-14 53.6 0.3 8.9e-12 45.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PFH32612.1 - 1.7e-09 38.0 0.3 7.6e-08 32.8 0.1 3.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH32612.1 - 2.2e-08 33.7 0.8 0.11 13.1 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 PFH32612.1 - 1.7e-05 25.0 0.2 0.0024 18.2 0.1 2.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 PFH32612.1 - 0.0061 17.0 6.7 6 7.5 0.3 4.1 4 0 0 4 4 4 2 Ankyrin repeat RRM_1 PF00076.22 PFH32613.1 - 2.4e-12 46.5 0.0 3.8e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 PFH32613.1 - 4.2e-07 29.8 1.7 9.1e-07 28.7 1.7 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 PFH32613.1 - 1.3e-06 28.1 0.8 2.9e-06 27.0 0.8 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PFH32613.1 - 1.9e-05 24.3 1.5 4e-05 23.3 1.5 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 PFH32613.1 - 0.00041 21.0 0.0 0.00097 19.8 0.0 1.6 1 0 0 1 1 1 1 Torus domain RRM_7 PF16367.5 PFH32613.1 - 0.0011 19.1 0.1 0.0043 17.1 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 PFH32613.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 PFH32613.1 - 0.0078 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH_3 PF15663.5 PFH32613.1 - 0.0086 16.3 0.2 0.025 14.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 PFH32613.1 - 0.081 13.4 0.7 0.24 11.9 0.7 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Pkinase PF00069.25 PFH32614.1 - 8.1e-30 104.1 0.0 3.2e-16 59.5 0.0 3.3 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32614.1 - 8e-12 45.0 0.1 4.5e-09 36.0 0.0 3.5 4 0 0 4 4 4 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH32614.1 - 0.0092 15.3 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 PFH32614.1 - 0.051 13.5 0.1 0.16 11.9 0.0 1.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 PFH32614.1 - 0.063 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L39 PF00832.20 PFH32616.1 - 1.5e-21 75.7 9.9 1.8e-21 75.5 9.9 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein zf-Tim10_DDP PF02953.15 PFH32617.1 - 1.1e-12 47.4 3.6 1.8e-12 46.7 3.6 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 PFH32617.1 - 0.015 14.9 3.1 0.023 14.4 3.1 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) ubiquitin PF00240.23 PFH32619.1 - 1.9e-24 85.2 0.6 2.1e-24 85.1 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PFH32619.1 - 1.9e-11 43.6 0.3 2.1e-11 43.5 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PFH32619.1 - 8.6e-05 22.9 0.1 0.00028 21.3 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 PFH32619.1 - 0.00033 20.7 0.1 0.00071 19.7 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PFH32619.1 - 0.004 17.7 0.0 0.0048 17.4 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 PFH32619.1 - 0.0041 17.4 0.1 0.005 17.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain UAA PF08449.11 PFH32621.1 - 3e-37 128.5 18.1 4e-37 128.1 18.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 PFH32621.1 - 9.7e-07 29.0 28.2 2.1e-05 24.7 5.9 3.0 2 1 1 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 PFH32621.1 - 0.005 15.8 5.5 0.005 15.8 5.5 1.7 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Glycophorin_A PF01102.18 PFH32621.1 - 0.048 13.9 0.0 0.13 12.5 0.0 1.6 2 0 0 2 2 2 0 Glycophorin A SlyX PF04102.12 PFH32622.1 - 0.0046 17.5 3.3 0.0046 17.5 3.3 22.2 12 6 10 23 23 23 1 SlyX Bromodomain PF00439.25 PFH32623.1 - 5.4e-23 80.9 0.0 9e-23 80.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 PFH32623.1 - 3e-12 46.8 0.3 1.8e-11 44.3 0.1 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PFH32623.1 - 6.1e-08 32.7 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PFH32623.1 - 9e-07 29.2 0.4 1.7e-06 28.3 0.4 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PFH32623.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 PFH32623.1 - 0.032 14.3 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CDP-OH_P_transf PF01066.21 PFH32624.1 - 4.1e-10 40.3 0.2 1.6e-09 38.4 0.2 2.1 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase HHV-5_US34A PF17087.5 PFH32624.1 - 7.7 6.8 8.2 1 9.5 2.3 2.2 2 0 0 2 2 2 0 Herpesvirus US34A protein family Prefoldin_2 PF01920.20 PFH32627.1 - 2.6e-08 33.8 10.1 6.1e-08 32.6 10.1 1.7 1 1 0 1 1 1 1 Prefoldin subunit TORC_M PF12885.7 PFH32627.1 - 0.0038 17.2 0.1 0.0052 16.7 0.1 1.2 1 0 0 1 1 1 1 Transducer of regulated CREB activity middle domain DUF87 PF01935.17 PFH32627.1 - 0.041 14.0 1.7 0.046 13.8 1.7 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain CdvA PF18822.1 PFH32627.1 - 0.046 13.6 1.4 0.046 13.6 1.4 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Jnk-SapK_ap_N PF09744.9 PFH32627.1 - 0.13 12.5 9.5 0.61 10.3 2.7 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.22 PFH32627.1 - 0.17 12.2 11.9 0.18 12.0 1.4 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain XhlA PF10779.9 PFH32627.1 - 0.25 11.6 7.0 0.24 11.6 1.0 2.2 2 0 0 2 2 2 0 Haemolysin XhlA FliJ PF02050.16 PFH32627.1 - 0.29 11.4 19.4 0.57 10.4 5.6 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein ZapB PF06005.12 PFH32627.1 - 0.32 11.5 13.1 3.2 8.3 0.9 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Spc7 PF08317.11 PFH32627.1 - 0.59 9.0 10.7 0.04 12.8 2.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Spc24 PF08286.11 PFH32627.1 - 0.74 10.1 9.8 1.3 9.3 3.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4472 PF14739.6 PFH32627.1 - 0.78 10.5 10.4 0.22 12.2 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) DUF1664 PF07889.12 PFH32627.1 - 1.2 9.2 10.1 1.4 9.0 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LUC7 PF03194.15 PFH32627.1 - 1.5 8.5 9.3 1.6 8.4 1.4 2.0 1 1 1 2 2 2 0 LUC7 N_terminus COG2 PF06148.11 PFH32627.1 - 1.7 8.7 8.8 5.7 7.0 0.8 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1515 PF07439.11 PFH32627.1 - 1.8 8.6 5.4 1.4e+02 2.6 5.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) STAT_alpha PF01017.20 PFH32627.1 - 1.9 8.4 11.2 22 4.9 11.1 2.0 1 1 0 1 1 1 0 STAT protein, all-alpha domain FlaC_arch PF05377.11 PFH32627.1 - 2.1 8.8 6.1 18 5.8 0.3 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) WXG100 PF06013.12 PFH32627.1 - 2.7 8.3 11.6 0.47 10.7 2.1 2.6 2 1 0 2 2 2 0 Proteins of 100 residues with WXG bZIP_2 PF07716.15 PFH32627.1 - 3.3 7.9 10.5 0.13 12.3 3.6 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF16 PF01519.16 PFH32627.1 - 3.7 8.1 10.1 2.5 8.6 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4404 PF14357.6 PFH32627.1 - 4.4 8.0 11.8 0.19 12.3 3.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) HALZ PF02183.18 PFH32627.1 - 5 7.4 11.8 2.2 8.6 4.9 2.6 2 1 0 2 2 2 0 Homeobox associated leucine zipper UPF0449 PF15136.6 PFH32627.1 - 8 7.0 8.9 5.1 7.6 3.5 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 GrpE PF01025.19 PFH32627.1 - 9.4 5.9 12.1 0.86 9.2 5.0 2.0 1 1 1 2 2 2 0 GrpE Methyltransf_16 PF10294.9 PFH32628.1 - 2.3e-16 60.0 0.1 3.8e-15 56.1 0.1 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Ank_2 PF12796.7 PFH32628.1 - 2.3e-12 47.3 0.0 3.5e-10 40.3 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PFH32628.1 - 1.2e-10 40.6 0.0 0.0051 17.2 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 PFH32628.1 - 7e-10 39.2 0.3 2.5e-06 27.9 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PFH32628.1 - 1.4e-09 37.9 0.1 0.012 16.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PFH32628.1 - 5.2e-07 29.8 0.0 0.011 16.0 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Methyltransf_23 PF13489.6 PFH32628.1 - 0.042 13.7 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 PFH32629.1 - 0.009 16.8 0.1 1.8 9.6 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF4106 PF13388.6 PFH32629.1 - 0.026 13.8 1.0 0.046 13.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Sel1 PF08238.12 PFH32630.1 - 5.4e-19 68.2 28.4 0.084 13.6 0.2 11.6 10 1 0 10 10 10 8 Sel1 repeat DUF4834 PF16118.5 PFH32631.1 - 1.5 9.8 4.4 3.3 8.7 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) WD40 PF00400.32 PFH32632.1 - 0.026 15.4 0.9 2.8 9.0 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat XPA_C PF05181.12 PFH32634.1 - 6e-06 26.1 0.0 9.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 XPA protein C-terminus eRF1_1 PF03463.15 PFH32635.1 - 7.2e-38 129.5 0.0 1.1e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 PFH32635.1 - 2.7e-18 66.5 0.0 5.6e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 PFH32635.1 - 9.7e-17 61.5 0.0 1.7e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 Ribosomal_L11_N PF03946.14 PFH32637.1 - 3.4e-20 71.6 0.1 5e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 PFH32637.1 - 8.2e-18 64.7 0.1 1.3e-17 64.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain PAN_1 PF00024.26 PFH32638.1 - 6.7e-46 154.2 55.0 7.4e-08 32.3 3.6 7.2 5 2 2 7 7 7 7 PAN domain PAN_4 PF14295.6 PFH32638.1 - 2.4e-39 133.0 42.4 1.1e-07 31.6 0.9 7.5 7 0 0 7 7 7 7 PAN domain PAN_2 PF08276.11 PFH32638.1 - 6.2e-05 23.0 43.4 0.052 13.7 0.8 7.0 7 0 0 7 7 7 5 PAN-like domain MANEC PF07502.14 PFH32638.1 - 0.00013 22.2 34.3 2.2 8.6 1.0 7.4 7 0 0 7 7 7 5 MANEC domain Patatin PF01734.22 PFH32639.1 - 0.0028 17.9 2.4 0.0062 16.7 1.9 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase SpoIIE PF07228.12 PFH32641.1 - 2.3e-16 60.3 0.3 4.6e-15 56.0 0.3 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 PFH32641.1 - 3.2e-08 33.5 0.2 1.5e-07 31.3 0.2 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 PFH32641.1 - 1.4e-06 28.1 0.1 0.00053 19.7 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C Ribosomal_L2_C PF03947.18 PFH32642.1 - 4.3e-50 169.1 1.3 4.3e-50 169.1 1.3 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 PFH32642.1 - 5.1e-21 74.4 0.1 8.6e-21 73.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain CRAL_TRIO PF00650.20 PFH32643.1 - 1.2e-23 83.6 0.0 1.7e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PFH32643.1 - 4.2e-05 23.7 0.1 8.3e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1682 PF07946.14 PFH32643.1 - 9.6 5.3 8.4 18 4.4 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ribosomal_L11_N PF03946.14 PFH32644.1 - 2.1e-21 75.5 0.1 3.1e-21 75.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 PFH32644.1 - 3.1e-19 69.3 0.0 5.2e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NOC3p PF07540.11 PFH32644.1 - 0.082 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Nucleolar complex-associated protein Guanylate_cyc PF00211.20 PFH32645.1 - 1.4e-78 262.8 0.0 2.4e-41 141.4 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 PFH32645.1 - 2.7e-50 171.4 21.2 2.7e-50 171.4 21.2 3.8 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PFH32645.1 - 5.4e-18 64.4 0.6 5.4e-18 64.4 0.6 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PFH32645.1 - 6.7e-09 36.3 0.2 0.003 17.9 0.0 3.5 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PFH32645.1 - 0.00011 22.1 0.0 0.00031 20.8 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PFH32645.1 - 0.0004 20.2 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PFH32645.1 - 0.0037 17.7 0.1 0.88 9.9 0.0 2.7 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PFH32645.1 - 0.0055 16.2 5.9 0.0084 15.6 0.0 3.6 3 1 0 3 3 3 1 E1-E2 ATPase DUF1053 PF06327.14 PFH32645.1 - 0.022 15.3 0.3 4.1 8.0 0.1 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) Kinase-like PF14531.6 PFH32647.1 - 2.5e-12 46.7 0.0 5.5e-12 45.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH32647.1 - 4.6e-06 26.2 0.0 8.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Glyco_hydro81C PF17652.1 PFH32649.1 - 2.3e-30 106.1 0.0 4.8e-30 105.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain SAYSvFN PF10260.9 PFH32650.1 - 3.5e-16 58.9 0.0 4.7e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) SEC-C PF02810.15 PFH32650.1 - 2.3e-06 27.4 11.7 3.4e-06 26.9 11.7 1.3 1 0 0 1 1 1 1 SEC-C motif Chromo_shadow PF01393.19 PFH32650.1 - 0.16 12.1 0.1 3.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Chromo shadow domain DUF2079 PF09852.9 PFH32650.1 - 0.16 10.8 0.6 0.21 10.4 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Lipase_3 PF01764.25 PFH32651.1 - 2.8e-08 33.8 0.0 5.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) SPX PF03105.19 PFH32651.1 - 0.34 10.8 8.7 0.57 10.0 8.7 1.3 1 0 0 1 1 1 0 SPX domain Mucin PF01456.17 PFH32651.1 - 2.8 7.9 9.2 0.12 12.3 3.1 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein F-box PF00646.33 PFH32652.1 - 0.00035 20.4 0.0 0.00092 19.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PFH32652.1 - 0.0062 16.4 0.3 0.0062 16.4 0.3 2.1 2 0 0 2 2 2 1 F-box-like RNA_pol_I_A49 PF06870.12 PFH32653.1 - 0.046 12.6 0.0 9.1 5.0 0.0 2.5 2 0 0 2 2 2 0 A49-like RNA polymerase I associated factor ABG_transport PF03806.13 PFH32653.1 - 0.18 10.0 0.8 0.29 9.3 0.8 1.1 1 0 0 1 1 1 0 AbgT putative transporter family RNA_pol_Rpb4 PF03874.16 PFH32656.1 - 1.8e-09 38.0 0.0 3.4e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb4 TRAM_LAG1_CLN8 PF03798.16 PFH32657.1 - 9e-21 74.5 6.4 9e-21 74.5 6.4 1.4 2 0 0 2 2 2 1 TLC domain Choline_sulf_C PF12411.8 PFH32658.1 - 0.2 11.5 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal CHCH PF06747.13 PFH32658.1 - 0.25 11.5 3.1 0.37 11.0 0.9 2.3 2 0 0 2 2 2 0 CHCH domain PRELI PF04707.14 PFH32659.1 - 7.4e-31 107.1 0.0 1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family RRM_1 PF00076.22 PFH32661.1 - 0.0025 17.6 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) partial_CstF PF15861.5 PFH32662.1 - 2.8e-22 78.3 0.4 4.8e-22 77.5 0.4 1.3 1 0 0 1 1 1 1 Partial cleavage stimulation factor domain RRM_1 PF00076.22 PFH32662.1 - 8.9e-09 35.1 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 PFH32662.1 - 1.2e-05 25.7 0.6 3.1e-05 24.3 0.6 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_7 PF16367.5 PFH32662.1 - 0.041 14.0 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif HGTP_anticodon PF03129.20 PFH32663.1 - 8.8e-23 80.3 0.0 1.6e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 PFH32663.1 - 4.2e-05 23.6 0.0 0.00018 21.5 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Pkinase PF00069.25 PFH32664.1 - 1.1e-68 231.5 0.0 1.3e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32664.1 - 3e-42 144.7 0.0 3.7e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH32664.1 - 3.4e-12 46.3 0.0 5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PFH32664.1 - 1.1e-08 34.7 0.4 2.2e-08 33.7 0.4 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH32664.1 - 3.3e-07 30.5 0.1 9.3e-05 22.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 PFH32664.1 - 5.1e-06 26.2 1.3 4.5e-05 23.1 1.3 2.0 1 1 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 PFH32664.1 - 0.00028 20.0 0.1 0.0004 19.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PFH32664.1 - 0.005 15.7 0.1 0.025 13.4 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 PFH32664.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 PFH32664.1 - 0.023 14.3 0.1 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Radial_spoke_3 PF06098.11 PFH32665.1 - 3.9e-60 203.6 7.8 3.9e-60 203.6 7.8 3.0 2 1 1 3 3 3 1 Radial spoke protein 3 AAA_23 PF13476.6 PFH32665.1 - 6.9 7.1 12.4 3.5 8.1 4.1 2.2 2 0 0 2 2 2 0 AAA domain CH_2 PF06294.11 PFH32667.1 - 0.00016 21.7 0.0 0.0004 20.4 0.0 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein DNA_RNApol_7kD PF03604.13 PFH32669.1 - 2.6e-15 55.8 6.8 3.4e-15 55.4 6.8 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 PFH32669.1 - 0.0038 17.2 0.5 0.0043 17.1 0.5 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GFA PF04828.14 PFH32669.1 - 0.0055 17.0 1.5 1.9 8.9 0.1 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 PFH32669.1 - 0.012 15.6 1.4 0.017 15.1 1.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-C2HC5 PF06221.13 PFH32669.1 - 0.014 15.3 1.1 0.018 15.0 1.1 1.1 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zinc-ribbon_6 PF10005.9 PFH32669.1 - 0.039 14.6 0.7 0.046 14.4 0.7 1.1 1 0 0 1 1 1 0 zinc-ribbon domain RAP PF08373.10 PFH32670.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 RAP domain Atg8 PF02991.16 PFH32671.1 - 2.3e-34 117.7 0.4 5.7e-34 116.4 0.4 1.6 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 PFH32671.1 - 6.7e-05 23.2 0.2 0.00027 21.3 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 tRNA-synt_1b PF00579.25 PFH32672.1 - 4.8e-34 118.0 0.0 2.8e-21 76.1 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 PFH32672.1 - 0.04 12.8 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Cyt-b5 PF00173.28 PFH32673.1 - 0.00068 19.7 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Zip PF02535.22 PFH32674.1 - 4.2e-19 69.0 0.1 6.9e-19 68.2 0.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter OPA3 PF07047.12 PFH32676.1 - 3.5e-32 110.8 0.3 5.4e-32 110.2 0.3 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) betaPIX_CC PF16523.5 PFH32676.1 - 0.05 13.4 0.3 0.095 12.5 0.3 1.4 1 0 0 1 1 1 0 betaPIX coiled coil zf-CDGSH PF09360.10 PFH32677.1 - 9.5e-16 57.8 5.9 4.9e-10 39.5 0.9 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type FAM221 PF14753.6 PFH32677.1 - 0.93 9.0 5.9 0.77 9.3 0.6 2.1 1 1 1 2 2 2 0 Protein FAM221A/B WD40 PF00400.32 PFH32678.1 - 0.0016 19.2 7.2 26 5.9 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat WEMBL PF05701.11 PFH32678.1 - 0.11 11.2 5.6 0.15 10.8 5.6 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Peptidase_S28 PF05577.12 PFH32679.1 - 3.5e-68 230.4 0.0 2.2e-66 224.4 0.0 2.2 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 PFH32679.1 - 0.0014 18.0 0.1 0.0022 17.3 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PFH32679.1 - 0.021 14.5 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3287 PF11690.8 PFH32681.1 - 0.035 13.8 0.7 0.069 12.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) zf-C4H2 PF10146.9 PFH32681.1 - 0.37 11.1 5.7 0.97 9.7 5.7 1.7 1 0 0 1 1 1 0 Zinc finger-containing protein adh_short PF00106.25 PFH32684.1 - 4e-30 104.7 0.5 1e-13 51.2 0.0 3.1 2 1 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 PFH32684.1 - 2.2e-15 56.9 6.2 2.5e-08 33.8 0.1 3.2 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PFH32684.1 - 0.00017 21.5 0.1 3 7.7 0.0 3.4 3 0 0 3 3 3 3 KR domain XAP5 PF04921.14 PFH32685.1 - 6.5e-71 239.1 23.0 3.6e-70 236.6 15.9 2.5 2 1 0 2 2 2 1 XAP5, circadian clock regulator Pkinase PF00069.25 PFH32686.1 - 3e-67 226.8 0.0 3.8e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32686.1 - 2.8e-33 115.3 0.0 4e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH32686.1 - 6.3e-06 25.7 0.0 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 PFH32686.1 - 0.0016 17.8 0.1 0.0031 16.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PFH32686.1 - 0.01 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase UDPGT PF00201.18 PFH32687.1 - 0.071 11.9 0.2 0.14 10.9 0.2 1.4 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Ephrin_rec_like PF07699.13 PFH32688.1 - 2.8e-19 68.6 488.0 0.00036 20.2 3.9 44.8 31 11 12 44 44 44 28 Putative ephrin-receptor like DUF202 PF02656.15 PFH32688.1 - 0.09 13.2 0.8 0.2 12.1 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF202) ETF_QO PF05187.13 PFH32688.1 - 3.5 7.8 7.4 12 6.1 2.2 4.9 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S ALAD PF00490.21 PFH32690.1 - 1.9e-130 434.7 0.6 2.4e-130 434.4 0.6 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase YL1 PF05764.13 PFH32690.1 - 0.025 14.7 14.9 0.051 13.7 14.9 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 PFH32690.1 - 0.062 11.5 6.1 0.088 11.0 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 PFH32690.1 - 0.098 12.2 3.0 0.18 11.4 3.0 1.5 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 PFH32690.1 - 0.17 10.1 4.5 0.25 9.6 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 PFH32690.1 - 4.6 6.6 9.1 7.8 5.8 9.1 1.3 1 0 0 1 1 1 0 SDA1 Peptidase_M16_C PF05193.21 PFH32691.1 - 1.3e-27 97.0 0.0 4.1e-13 49.7 0.0 3.8 3 2 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PFH32691.1 - 1.5e-12 47.8 2.9 1.9e-10 40.9 2.8 3.2 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Apocytochr_F_N PF16639.5 PFH32691.1 - 0.16 12.3 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Apocytochrome F, N-terminal ELO PF01151.18 PFH32692.1 - 6.1e-52 176.6 17.9 9.5e-52 176.0 17.9 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family Pkinase_Tyr PF07714.17 PFH32695.1 - 7.5e-36 123.7 0.0 1.7e-35 122.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PFH32695.1 - 4.5e-33 114.7 0.0 1.5e-32 113.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 PFH32695.1 - 0.019 13.7 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 PFH32695.1 - 0.12 11.8 0.2 0.36 10.2 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_2 PF07647.17 PFH32695.1 - 0.22 11.6 0.0 0.43 10.7 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) zf-CCHC_4 PF14392.6 PFH32696.1 - 4 7.2 30.8 0.052 13.3 3.1 4.4 4 0 0 4 4 4 0 Zinc knuckle IMP2_N PF18590.1 PFH32698.1 - 9.3e-17 61.4 0.0 1.4e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 PFH32698.1 - 2.8e-06 27.1 0.1 4.8e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) C-terminal domain FHA PF00498.26 PFH32699.1 - 0.0013 19.0 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 2 FHA domain Golgin_A5 PF09787.9 PFH32699.1 - 0.0035 16.9 26.7 0.0051 16.3 26.7 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Macoilin PF09726.9 PFH32699.1 - 0.28 9.7 12.1 0.41 9.1 12.1 1.2 1 0 0 1 1 1 0 Macoilin family DUF1664 PF07889.12 PFH32699.1 - 2.3 8.3 9.3 2.3 8.2 4.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 PFH32699.1 - 2.7 6.8 4.3 5.3 5.8 4.3 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_11 PF13086.6 PFH32699.1 - 3.6 7.3 8.2 7 6.3 8.2 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_L27A PF00828.19 PFH32700.1 - 6.4e-16 59.2 0.1 9.2e-15 55.4 0.0 2.2 1 1 1 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GTP_cyclohydroI PF01227.22 PFH32701.1 - 3.2e-64 215.7 0.0 4.6e-64 215.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 PFH32701.1 - 0.00052 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein PLU-1 PF08429.11 PFH32703.1 - 1.6e-22 80.2 29.9 7.8e-13 48.3 3.1 6.0 5 1 1 6 6 6 5 PLU-1-like protein PLU-1 PF08429.11 PFH32704.1 - 2.3e-07 30.3 20.5 7e-05 22.1 3.4 4.3 4 1 1 5 5 5 3 PLU-1-like protein PHD PF00628.29 PFH32704.1 - 0.082 12.8 0.0 0.082 12.8 0.0 2.0 2 0 0 2 2 2 0 PHD-finger DUF2383 PF09537.10 PFH32704.1 - 9.3 6.6 9.6 0.33 11.3 0.7 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF2383) Cse1 PF08506.10 PFH32706.1 - 3.8e-86 289.2 0.0 1.9e-85 286.9 0.0 2.1 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 PFH32706.1 - 1.5e-63 214.8 0.6 2.9e-63 213.9 0.6 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 PFH32706.1 - 2.1e-11 43.6 1.5 4.3e-09 36.1 0.0 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 PFH32706.1 - 0.068 13.2 13.2 5.8 7.1 0.1 6.2 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat Xpo1 PF08389.12 PFH32706.1 - 0.09 12.8 1.6 2.4 8.2 0.1 3.4 3 0 0 3 3 3 0 Exportin 1-like protein CLASP_N PF12348.8 PFH32706.1 - 4.1 6.9 6.9 4.7 6.7 0.2 3.6 3 1 0 3 3 3 0 CLASP N terminal MFS_1 PF07690.16 PFH32708.1 - 1.3e-22 80.2 60.1 3e-19 69.2 17.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 PFH32708.1 - 8e-10 38.2 13.8 8e-10 38.2 13.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 PFH32708.1 - 3.1e-08 32.4 20.8 0.00031 19.2 0.1 4.0 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Spec3 PF15795.5 PFH32710.1 - 0.43 11.1 12.9 2 9.0 4.5 2.3 1 1 1 2 2 2 0 Ectodermal ciliogenesis protein DnaJ_C PF01556.18 PFH32712.1 - 8.3e-26 90.8 0.0 1.8e-25 89.7 0.0 1.6 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 PFH32712.1 - 2.4e-10 40.6 15.1 7e-10 39.1 15.1 1.9 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 PFH32712.1 - 0.013 15.5 15.9 0.25 11.3 5.2 2.8 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 PFH32712.1 - 5.2 7.3 16.2 4 7.7 0.1 4.4 4 0 0 4 4 4 0 Family of unknown function (DUF5351) Ion_trans PF00520.31 PFH32713.1 - 0.00013 21.3 9.8 0.00017 20.9 9.8 1.1 1 0 0 1 1 1 1 Ion transport protein NRDE-2 PF08424.10 PFH32714.1 - 0.00045 19.5 0.0 0.0086 15.2 0.0 2.5 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference KGG PF10685.9 PFH32714.1 - 9 6.7 8.8 24 5.3 1.9 3.3 2 0 0 2 2 2 0 Stress-induced bacterial acidophilic repeat motif Pkinase PF00069.25 PFH32716.1 - 2e-35 122.5 0.0 1.3e-11 44.4 0.0 4.2 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32716.1 - 7.9e-07 28.6 0.0 0.0015 17.9 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 PFH32716.1 - 0.03 14.3 1.4 0.21 11.5 1.4 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF4111 PF13427.6 PFH32717.1 - 0.87 9.8 7.1 0.15 12.2 2.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4111) WD40 PF00400.32 PFH32719.1 - 3e-07 31.0 1.7 0.14 13.1 0.0 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat RNase_P_Rpp14 PF01900.19 PFH32721.1 - 2.8e-14 53.2 0.0 3.7e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family U3_assoc_6 PF08640.11 PFH32722.1 - 1.7e-13 50.5 0.2 1.7e-13 50.5 0.2 2.1 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 EamA PF00892.20 PFH32723.1 - 6.8e-06 26.3 22.2 8.2e-05 22.8 3.4 2.4 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 PFH32723.1 - 1.6e-05 24.4 12.6 2e-05 24.1 12.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 PFH32723.1 - 0.002 17.3 9.9 0.0038 16.4 9.9 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 PFH32723.1 - 0.0025 17.1 12.9 0.0032 16.7 12.9 1.1 1 0 0 1 1 1 1 UAA transporter family TMEM234 PF10639.9 PFH32723.1 - 0.0031 17.5 0.1 0.0031 17.5 0.1 2.5 3 1 0 3 3 3 1 Putative transmembrane family 234 Multi_Drug_Res PF00893.19 PFH32723.1 - 0.0047 17.6 0.3 0.0047 17.6 0.3 3.1 3 1 0 3 3 3 1 Small Multidrug Resistance protein IFT57 PF10498.9 PFH32724.1 - 1e-56 192.5 4.9 1.9e-32 112.7 12.3 2.0 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 Exonuc_VII_L PF02601.15 PFH32724.1 - 0.0028 17.3 0.7 0.0033 17.0 0.7 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit PEPcase PF00311.17 PFH32724.1 - 0.018 13.1 3.6 0.023 12.8 3.6 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase M_domain PF12938.7 PFH32724.1 - 0.023 14.5 3.6 0.037 13.8 3.6 1.3 1 0 0 1 1 1 0 M domain of GW182 Effector_1 PF04518.12 PFH32724.1 - 0.039 13.1 2.2 0.058 12.5 2.2 1.3 1 0 0 1 1 1 0 Effector from type III secretion system Prominin PF05478.11 PFH32724.1 - 0.13 10.2 2.7 0.085 10.8 0.6 1.5 1 1 0 1 1 1 0 Prominin APG6_N PF17675.1 PFH32724.1 - 0.18 12.3 12.8 0.075 13.6 8.7 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 PFH32724.1 - 0.38 11.0 17.3 0.48 10.6 5.7 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Occludin_ELL PF07303.13 PFH32724.1 - 0.78 10.5 10.2 2.1 9.1 5.5 2.3 1 1 1 2 2 2 0 Occludin homology domain Fzo_mitofusin PF04799.13 PFH32724.1 - 0.85 9.2 8.8 4.8 6.7 5.6 2.2 2 0 0 2 2 2 0 fzo-like conserved region TMF_TATA_bd PF12325.8 PFH32724.1 - 1 9.6 13.5 32 4.8 12.6 3.2 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Phage_GPO PF05929.11 PFH32724.1 - 1 8.9 6.3 1.7 8.2 6.3 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Cauli_AT PF03233.13 PFH32724.1 - 1.1 9.2 2.8 1.8 8.5 0.7 1.9 1 1 1 2 2 2 0 Aphid transmission protein Spectrin PF00435.21 PFH32724.1 - 1.6 9.2 15.0 4.3 7.9 5.2 2.8 1 1 0 2 2 2 0 Spectrin repeat Fib_alpha PF08702.10 PFH32724.1 - 1.8 8.7 8.3 9.8 6.4 4.0 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 PFH32724.1 - 2.2 8.3 6.3 13 5.9 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YlqD PF11068.8 PFH32724.1 - 2.6 8.4 15.4 13 6.2 15.1 2.0 1 1 0 1 1 1 0 YlqD protein COG2 PF06148.11 PFH32724.1 - 2.9 8.0 6.9 6.9 6.8 3.1 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Bacillus_HBL PF05791.11 PFH32724.1 - 3.3 7.5 7.1 3.1 7.6 3.1 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4407 PF14362.6 PFH32724.1 - 5.8 6.2 9.4 27 4.0 9.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) THOC7 PF05615.13 PFH32724.1 - 6.3 7.1 11.9 20 5.5 10.9 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 MRP-S26 PF14943.6 PFH32724.1 - 6.7 6.6 10.6 11 5.8 10.7 1.3 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 CENP-H PF05837.12 PFH32724.1 - 7.7 7.0 11.9 1.3 9.4 6.1 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FapA PF03961.13 PFH32724.1 - 8.5 4.9 9.4 6.5 5.2 5.8 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A Nup88 PF10168.9 PFH32724.1 - 8.9 4.0 13.1 12 3.5 13.1 1.1 1 0 0 1 1 1 0 Nuclear pore component Nup188_C PF18378.1 PFH32725.1 - 0.24 10.2 0.9 0.37 9.6 0.9 1.1 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain TP6A_N PF04406.14 PFH32726.1 - 5.6e-13 48.7 0.1 1.1e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2220 PF09983.9 PFH32726.1 - 0.0024 17.3 0.0 0.0041 16.5 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) DUF4704 PF15787.5 PFH32726.1 - 0.0079 15.5 0.2 0.01 15.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) IMCp PF12314.8 PFH32727.1 - 7.1e-23 80.7 119.8 8.8e-12 45.2 20.0 7.2 1 1 5 6 6 6 5 Inner membrane complex protein Pkinase PF00069.25 PFH32728.1 - 2.7e-31 108.9 0.0 6.4e-19 68.3 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32728.1 - 4.6e-10 39.2 0.0 0.0025 17.2 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase WD40 PF00400.32 PFH32729.1 - 3.2e-12 46.8 18.3 0.00045 21.0 0.1 8.2 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH32729.1 - 0.0053 17.0 0.1 2.3 8.6 0.0 3.3 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 PFH32729.1 - 0.63 10.6 6.4 48 4.6 0.0 5.1 6 0 0 6 6 6 0 PQQ-like domain Asn_synthase PF00733.21 PFH32730.1 - 1.1e-91 308.2 0.9 5.8e-50 170.9 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 PFH32730.1 - 5.6e-33 113.5 0.0 9e-33 112.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 PFH32730.1 - 6e-19 68.6 0.0 1.3e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 PFH32730.1 - 3.2e-10 39.9 0.1 1e-09 38.2 0.1 1.8 1 1 0 1 1 1 1 Aluminium induced protein NMT1_3 PF16868.5 PFH32730.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family PQ-loop PF04193.14 PFH32731.1 - 3.6e-20 71.5 1.3 1.9e-09 37.1 0.5 2.2 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 PFH32731.1 - 0.018 15.1 0.3 1.4 9.0 0.0 2.4 1 1 1 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF4396 PF14342.6 PFH32732.1 - 0.15 12.4 1.6 0.5 10.7 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) PRKCSH-like PF12999.7 PFH32734.1 - 4.6e-12 46.1 11.4 1.9e-05 24.6 0.3 3.5 3 0 0 3 3 3 3 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 PFH32734.1 - 2.2e-07 30.7 0.0 2.2e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Senescence PF06911.12 PFH32734.1 - 0.019 15.3 0.7 0.053 13.8 0.7 1.7 1 0 0 1 1 1 0 Senescence-associated protein PRKCSH PF07915.13 PFH32734.1 - 0.029 15.4 0.0 0.12 13.4 0.0 2.1 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein E1-E2_ATPase PF00122.20 PFH32736.1 - 3.3e-35 121.2 0.5 3.3e-35 121.2 0.5 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 PFH32736.1 - 3.3e-22 79.8 0.0 1.9e-17 64.2 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HMA PF00403.26 PFH32736.1 - 1.4e-21 76.7 0.0 1.4e-12 47.9 0.0 2.9 3 0 0 3 3 3 2 Heavy-metal-associated domain Tox-PL-2 PF15643.6 PFH32736.1 - 0.0046 17.1 0.0 0.76 9.9 0.0 2.3 2 0 0 2 2 2 1 Papain fold toxin 2 Hydrolase_3 PF08282.12 PFH32736.1 - 0.02 14.6 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Oxidored_q2 PF00420.24 PFH32736.1 - 0.43 10.2 3.9 0.16 11.6 0.3 2.1 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Kinase-like PF14531.6 PFH32738.1 - 4e-45 154.4 0.0 6.1e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH32738.1 - 1.5e-16 60.5 0.0 9.7e-16 57.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32738.1 - 3.7e-10 39.5 0.0 8.1e-10 38.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PFH32738.1 - 0.0014 18.0 0.1 0.0026 17.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YTH PF04146.15 PFH32739.1 - 3.1e-34 118.3 0.1 1e-32 113.4 0.1 2.2 1 1 0 1 1 1 1 YT521-B-like domain Torus PF16131.5 PFH32739.1 - 4e-06 27.5 7.9 5.5e-05 23.8 0.4 2.8 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 PFH32739.1 - 0.087 12.8 12.3 0.11 12.5 1.9 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PFH32739.1 - 0.46 10.6 22.8 0.12 12.5 5.2 3.2 3 0 0 3 3 3 0 Zinc finger domain ATP12 PF07542.11 PFH32740.1 - 0.00075 19.6 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 2 ATP12 chaperone protein Kinase-like PF14531.6 PFH32741.1 - 3.5e-43 148.0 0.0 4.8e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH32741.1 - 1.5e-09 37.6 0.0 0.00044 19.7 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32741.1 - 1.5e-05 24.4 0.0 5e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PFH32741.1 - 0.0045 16.6 0.0 0.01 15.5 0.0 1.5 2 0 0 2 2 2 1 RIO1 family zf-B_box PF00643.24 PFH32742.1 - 4.4e-11 42.8 13.5 3.5e-06 27.1 3.3 2.3 2 0 0 2 2 2 2 B-box zinc finger ATP-synt_D PF01813.17 PFH32742.1 - 0.013 15.3 0.4 0.022 14.6 0.4 1.3 1 0 0 1 1 1 0 ATP synthase subunit D DUF1731 PF08338.11 PFH32742.1 - 0.068 13.0 0.0 0.22 11.4 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1731) XPA_N PF01286.18 PFH32742.1 - 1 9.5 0.0 1 9.5 0.0 3.1 3 0 0 3 3 3 0 XPA protein N-terminal Kinesin PF00225.23 PFH32743.1 - 1.9e-07 30.4 0.0 4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PFH32743.1 - 0.00021 21.2 0.0 0.00046 20.1 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding UBA2_C PF16195.5 PFH32743.1 - 0.036 14.8 0.9 0.23 12.2 0.9 2.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Cytomega_TRL10 PF06084.11 PFH32743.1 - 0.07 13.1 0.3 0.17 11.9 0.3 1.6 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein PRCC PF10253.9 PFH32743.1 - 0.27 12.0 4.4 2.7 8.7 2.9 2.8 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting PHD PF00628.29 PFH32745.1 - 0.00011 22.0 5.9 0.00046 20.0 5.9 2.1 1 0 0 1 1 1 1 PHD-finger Sugar_tr PF00083.24 PFH32746.1 - 8.8e-39 133.6 17.5 2.7e-38 132.0 17.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PFH32746.1 - 3.6e-18 65.6 26.9 3.6e-18 65.6 26.9 2.3 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 PFH32746.1 - 8.9e-07 27.7 3.1 1.8e-06 26.7 3.1 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 PFH32746.1 - 0.02 13.1 0.6 0.035 12.3 0.6 1.3 1 0 0 1 1 1 0 BT1 family eIF3_subunit PF08597.10 PFH32747.1 - 4.7 7.1 10.5 12 5.7 10.5 1.7 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Mobilization_B PF17511.2 PFH32747.1 - 4.7 7.6 7.1 1 9.7 0.6 2.9 2 1 1 3 3 3 0 Mobilization protein B DUF4129 PF13559.6 PFH32747.1 - 7.5 6.9 16.7 2 8.7 1.3 4.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4129) Chorismate_synt PF01264.21 PFH32748.1 - 6.8e-122 406.2 0.0 8.2e-122 406.0 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase SAP18 PF06487.12 PFH32749.1 - 3.9e-30 104.9 0.0 3.9e-30 104.9 0.0 2.7 4 1 0 4 4 4 1 Sin3 associated polypeptide p18 (SAP18) PP2C PF00481.21 PFH32750.1 - 1.8e-32 113.0 0.0 1.2e-24 87.4 0.0 2.4 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 PFH32750.1 - 0.014 15.3 0.0 0.25 11.2 0.0 2.4 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) DnaJ PF00226.31 PFH32753.1 - 7.6e-13 48.4 0.2 1.7e-12 47.3 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Myc-LZ PF02344.15 PFH32753.1 - 0.082 13.0 2.2 0.33 11.1 2.2 2.1 1 0 0 1 1 1 0 Myc leucine zipper domain PCI PF01399.27 PFH32754.1 - 0.0009 19.7 0.1 0.0088 16.5 0.1 2.7 1 0 0 1 1 1 1 PCI domain BT1 PF03092.16 PFH32755.1 - 9.2e-80 268.3 24.2 1.5e-55 188.5 12.2 2.1 1 1 1 2 2 2 2 BT1 family MFS_1 PF07690.16 PFH32755.1 - 0.00019 20.5 43.8 0.0098 14.9 10.8 4.4 2 2 0 4 4 4 3 Major Facilitator Superfamily WD40 PF00400.32 PFH32756.1 - 4.5e-23 81.1 13.1 0.00085 20.1 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat WD40 PF00400.32 PFH32757.1 - 2.6e-18 66.0 8.3 9.9e-06 26.2 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat HHH_8 PF14716.6 PFH32757.1 - 0.016 15.6 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Nup160 PF11715.8 PFH32757.1 - 0.022 13.4 0.2 4.5 5.8 0.0 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Methyltransf_PK PF05891.12 PFH32758.1 - 1.4e-69 234.0 0.0 1.7e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 PFH32758.1 - 3.1e-08 34.2 0.0 6.6e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PFH32758.1 - 2.6e-07 31.2 0.0 4.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 PFH32758.1 - 6.6e-06 25.6 0.0 1.2e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 PFH32758.1 - 3.4e-05 24.5 0.0 7.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PFH32758.1 - 0.00022 21.1 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Bin3 PF06859.12 PFH32758.1 - 0.059 14.0 0.0 0.099 13.3 0.0 1.4 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Tctex-1 PF03645.13 PFH32760.1 - 7.5e-21 74.3 0.1 8.6e-21 74.1 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family Cullin PF00888.22 PFH32762.1 - 4.8e-179 596.9 0.0 6e-179 596.6 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 PFH32762.1 - 9.6e-25 86.4 0.4 2.5e-24 85.1 0.4 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain TraI_2 PF07514.11 PFH32763.1 - 0.044 12.7 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative helicase TSP_1 PF00090.19 PFH32764.1 - 7.1e-34 115.8 79.4 2.5e-08 34.0 1.7 7.4 6 2 0 6 6 6 6 Thrombospondin type 1 domain VWA PF00092.28 PFH32764.1 - 7.7e-30 104.4 0.0 1.1e-29 103.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PFH32764.1 - 4.4e-15 56.3 0.0 8e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PFH32764.1 - 0.00076 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PFH32764.1 - 0.0054 16.2 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 PFH32764.1 - 0.16 12.1 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus FHA PF00498.26 PFH32765.1 - 2.6e-16 59.7 0.0 4.9e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PFH32765.1 - 5.3e-07 29.9 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Thioredoxin PF00085.20 PFH32766.1 - 1.7e-06 27.9 0.0 2.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 PFH32766.1 - 0.0016 18.4 0.0 0.0021 18.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Ribosomal_L37 PF08561.10 PFH32770.1 - 0.00012 22.6 1.1 0.0012 19.4 0.2 2.2 1 1 0 2 2 2 1 Mitochondrial ribosomal protein L37 Asp PF00026.23 PFH32771.1 - 3.5e-78 263.2 0.0 5.8e-78 262.5 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 PFH32771.1 - 1e-08 35.6 0.7 6.9e-07 29.7 0.6 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 PFH32771.1 - 0.015 15.9 0.1 0.93 10.2 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease Spo12 PF05032.12 PFH32771.1 - 0.029 14.3 0.1 0.057 13.3 0.1 1.5 1 0 0 1 1 1 0 Spo12 family TAXi_C PF14541.6 PFH32771.1 - 0.044 13.6 0.0 0.098 12.4 0.0 1.6 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal DUF2555 PF10742.9 PFH32772.1 - 0.078 12.8 0.3 0.15 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) TPR_19 PF14559.6 PFH32773.1 - 1.3e-07 32.0 13.3 0.00018 21.9 0.7 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 PFH32773.1 - 2.8e-05 23.9 10.5 0.11 12.6 0.1 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 PFH32773.1 - 0.00011 21.9 5.8 0.43 10.5 0.1 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 PFH32773.1 - 0.00064 19.7 0.1 2.6 8.5 0.0 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 PFH32773.1 - 0.0084 15.4 9.1 0.34 10.1 0.5 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 PFH32773.1 - 0.029 14.0 2.7 5.1 6.9 0.4 3.2 3 0 0 3 3 3 0 TPR repeat HrpB1_HrpK PF09613.10 PFH32773.1 - 0.22 11.2 2.5 6.3 6.5 0.1 2.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF5538 PF17692.1 PFH32773.1 - 0.35 10.9 2.9 91 3.1 0.2 3.7 3 0 0 3 3 3 0 Family of unknown function (DUF5538) TPR_14 PF13428.6 PFH32773.1 - 0.79 10.7 39.5 1.6 9.8 0.3 9.2 8 2 2 10 10 9 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH32773.1 - 0.83 9.9 7.9 1.3 9.3 0.1 4.2 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PFH32773.1 - 0.92 10.0 5.0 98 3.7 0.0 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat UCR_UQCRX_QCR9 PF05365.12 PFH32774.1 - 6e-15 54.9 1.8 9.2e-15 54.3 1.8 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like SurA_N_3 PF13624.6 PFH32775.1 - 0.21 11.4 3.2 0.45 10.3 3.2 1.5 1 0 0 1 1 1 0 SurA N-terminal domain MORN PF02493.20 PFH32776.1 - 3.6e-40 133.5 69.5 7.8e-07 28.6 1.6 10.1 10 0 0 10 10 10 9 MORN repeat DUF3086 PF11285.8 PFH32776.1 - 0.36 9.9 0.6 12 4.9 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3086) DUF3048_C PF17479.2 PFH32776.1 - 0.97 9.8 11.0 15 6.0 2.1 4.2 2 2 1 4 4 4 0 Protein of unknown function (DUF3048) C-terminal domain Flagellin_N PF00669.20 PFH32778.1 - 0.13 12.3 5.4 0.31 11.1 1.0 2.8 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region DUF812 PF05667.11 PFH32778.1 - 0.44 9.4 5.5 0.14 11.0 2.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Spc7 PF08317.11 PFH32778.1 - 6 5.7 9.1 11 4.8 9.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HSP70 PF00012.20 PFH32779.1 - 5e-14 51.4 0.2 5.2e-10 38.1 0.0 2.7 2 1 1 3 3 3 2 Hsp70 protein TPR_1 PF00515.28 PFH32779.1 - 0.00016 21.3 0.0 0.23 11.4 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 PFH32779.1 - 0.00075 19.4 0.0 3 8.2 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 PFH32779.1 - 0.05 13.3 0.1 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 TPR repeat HSP70 PF00012.20 PFH32780.1 - 1.2e-23 83.2 0.1 6.5e-16 57.6 0.0 3.2 2 1 1 3 3 3 3 Hsp70 protein TPR_1 PF00515.28 PFH32780.1 - 0.0035 17.1 4.5 0.21 11.5 0.4 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH32780.1 - 0.0039 17.4 0.4 0.016 15.4 0.4 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PFH32780.1 - 0.0053 17.2 4.1 0.0067 16.9 1.9 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 PFH32780.1 - 0.0099 15.9 5.8 0.069 13.3 0.9 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 PFH32780.1 - 0.061 13.7 0.4 0.23 11.9 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Antirestrict PF03230.13 PFH32780.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Antirestriction protein TPR_14 PF13428.6 PFH32780.1 - 0.62 11.0 3.8 2.1 9.4 0.9 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PFH32780.1 - 1.5 9.2 4.2 5.4 7.5 0.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 PFH32780.1 - 1.7 8.9 6.0 1.4 9.1 0.7 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat FAP PF07174.11 PFH32781.1 - 0.002 17.6 3.7 0.002 17.6 3.7 1.1 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) T2SS-T3SS_pil_N PF13629.6 PFH32781.1 - 1.2 9.0 5.2 7.7 6.3 1.8 2.5 1 1 1 2 2 2 0 Pilus formation protein N terminal region SH3_3 PF08239.11 PFH32783.1 - 0.027 14.8 0.2 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain PARP PF00644.20 PFH32784.1 - 4.3e-11 42.8 0.0 2.7e-08 33.6 0.0 2.6 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Ig_C17orf99 PF17736.1 PFH32787.1 - 0.046 13.8 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 C17orf99 Ig domain RAP PF08373.10 PFH32788.1 - 0.0089 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 RAP domain YgbB PF02542.16 PFH32789.1 - 0.025 14.9 0.1 0.036 14.3 0.1 1.2 1 0 0 1 1 1 0 YgbB family Menin PF05053.13 PFH32791.1 - 0.069 11.5 2.2 0.075 11.4 2.2 1.1 1 0 0 1 1 1 0 Menin Herpes_pp85 PF04637.12 PFH32791.1 - 0.1 11.0 4.3 0.12 10.8 4.3 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Mito_fiss_reg PF05308.11 PFH32791.1 - 3.3 7.7 6.9 1 9.4 0.2 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator ATF7IP_BD PF16788.5 PFH32791.1 - 7.9 6.5 14.3 2.3 8.3 10.9 1.8 2 0 0 2 2 2 0 ATF-interacting protein binding domain PH PF00169.29 PFH32792.1 - 7.7e-14 52.1 0.4 0.0004 20.9 0.0 5.7 5 2 1 6 6 6 3 PH domain DUF948 PF06103.11 PFH32792.1 - 0.087 13.1 2.2 22 5.4 0.1 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3829 PF12889.7 PFH32792.1 - 0.19 11.1 2.1 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Atg14 PF10186.9 PFH32792.1 - 0.68 9.0 21.8 0.011 14.9 11.6 2.3 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ECH_1 PF00378.20 PFH32793.1 - 1.9e-47 161.7 0.0 2.4e-24 86.0 0.0 3.1 3 0 0 3 3 3 3 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PFH32793.1 - 5.6e-26 91.8 0.1 1e-16 61.4 0.0 3.6 2 1 1 4 4 4 3 Enoyl-CoA hydratase/isomerase ABC1 PF03109.16 PFH32794.1 - 1.4e-29 102.6 0.1 3.2e-29 101.5 0.1 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 PFH32794.1 - 0.02 14.8 0.6 0.059 13.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribonuc_P_40 PF08584.11 PFH32795.1 - 3.9e-06 26.3 0.0 1.9e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit Tub PF01167.18 PFH32797.1 - 1.6e-25 90.3 0.0 1.5e-20 74.0 0.0 4.0 3 1 0 3 3 3 2 Tub family DNA_pol_phi PF04931.13 PFH32799.1 - 4.5 5.2 11.0 5.2 5.0 11.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi PP2C_C PF07830.13 PFH32799.1 - 5.6 7.5 7.7 1.1e+02 3.4 0.0 2.4 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Hist_deacetyl PF00850.19 PFH32801.1 - 8.5e-55 186.4 0.0 8e-54 183.2 0.0 2.5 2 1 0 2 2 2 1 Histone deacetylase domain Ank_2 PF12796.7 PFH32801.1 - 1.2e-11 45.0 0.2 2.8e-06 27.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PFH32801.1 - 1.1e-09 37.6 1.6 0.033 14.7 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 PFH32801.1 - 6.6e-09 36.1 6.3 0.00055 20.4 0.2 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PFH32801.1 - 6.9e-09 35.8 4.3 0.0012 19.2 0.1 4.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PFH32801.1 - 0.0001 22.5 4.5 0.23 11.8 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) RAP PF08373.10 PFH32802.1 - 2.9e-07 30.5 0.2 3.4e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 RAP domain FAST_1 PF06743.15 PFH32802.1 - 0.00031 20.6 1.2 2.5 8.1 0.0 4.8 4 0 0 4 4 4 2 FAST kinase-like protein, subdomain 1 MTES_1575 PF18741.1 PFH32802.1 - 0.013 15.7 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 REase_MTES_1575 WD40 PF00400.32 PFH32805.1 - 1.3e-08 35.3 12.1 2.6 9.1 0.1 9.5 9 0 0 9 9 9 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 PFH32805.1 - 0.17 10.6 0.0 0.73 8.5 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like Kelch_4 PF13418.6 PFH32806.1 - 1.5e-08 34.5 0.2 1.4e-05 25.0 0.1 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.25 PFH32806.1 - 5e-07 29.2 0.1 0.00019 20.9 0.1 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 PFH32806.1 - 0.00067 19.9 0.2 0.0026 18.0 0.1 2.1 2 0 0 2 2 2 1 Galactose oxidase, central domain EGF_2 PF07974.13 PFH32806.1 - 0.0016 18.8 16.4 0.0037 17.6 16.4 1.6 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 PFH32806.1 - 0.0026 18.0 2.8 0.0061 16.8 2.8 1.6 1 0 0 1 1 1 1 EB module Kelch_5 PF13854.6 PFH32806.1 - 0.0044 17.0 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 PFH32806.1 - 0.023 14.7 1.0 0.77 9.8 0.5 3.0 2 1 0 2 2 2 0 Kelch motif I-EGF_1 PF18372.1 PFH32806.1 - 0.037 14.1 11.1 0.037 14.1 11.1 2.0 2 1 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 hEGF PF12661.7 PFH32806.1 - 0.063 13.9 11.1 0.063 13.9 11.1 2.0 2 0 0 2 2 1 0 Human growth factor-like EGF EGF PF00008.27 PFH32806.1 - 0.18 12.2 9.6 0.53 10.6 9.6 1.8 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 PFH32806.1 - 0.23 11.6 10.1 0.62 10.2 10.1 1.7 1 0 0 1 1 1 0 Tenascin EGF domain Phage_holin_2_3 PF16080.5 PFH32806.1 - 0.37 10.6 1.1 0.66 9.8 1.1 1.4 1 0 0 1 1 1 0 Bacteriophage holin family HP1 Ham1p_like PF01725.16 PFH32808.1 - 1.1e-49 168.9 0.0 1.3e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_M22 PF00814.25 PFH32809.1 - 6.2e-72 242.6 0.3 2.4e-50 171.8 0.1 3.1 2 1 0 2 2 2 2 Glycoprotease family Methyltransf_23 PF13489.6 PFH32812.1 - 2.8e-13 50.0 0.0 5.7e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH32812.1 - 1.5e-09 38.5 0.0 0.00072 20.3 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 PFH32812.1 - 3.1e-08 34.2 0.0 0.0016 19.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 PFH32812.1 - 1.3e-05 25.7 0.0 0.27 11.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 PFH32812.1 - 0.00031 20.6 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 PFH32812.1 - 0.0046 16.5 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 PFH32812.1 - 0.0049 16.1 0.0 0.0096 15.1 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.17 PFH32812.1 - 0.0063 16.0 0.0 0.022 14.2 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 PFH32812.1 - 0.016 14.5 0.0 0.038 13.3 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase domain Pro_dh PF01619.18 PFH32813.1 - 9.3e-70 235.5 0.0 6.1e-45 154.0 0.0 3.0 3 0 0 3 3 3 3 Proline dehydrogenase Ribosomal_L21p PF00829.21 PFH32814.1 - 9.6e-17 61.1 0.4 2.7e-16 59.7 0.1 1.9 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein AP2 PF00847.20 PFH32816.1 - 3e-06 27.4 0.0 1.1e-05 25.6 0.0 2.0 1 0 0 1 1 1 1 AP2 domain ABC1 PF03109.16 PFH32817.1 - 8.8e-35 119.4 0.0 1.5e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family DUF993 PF06187.11 PFH32817.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF993) Mto2_bdg PF12808.7 PFH32817.1 - 0.37 11.1 3.1 1.5 9.2 0.9 3.0 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4551 PF15087.6 PFH32820.1 - 0.31 9.8 3.1 0.51 9.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CCDC106 PF15794.5 PFH32823.1 - 0.0065 16.2 1.1 0.0065 16.2 1.1 3.2 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 106 DHHC PF01529.20 PFH32824.1 - 5.2e-36 123.7 12.5 1.1e-35 122.6 12.5 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Rab5ip PF07019.12 PFH32824.1 - 0.085 13.5 2.7 0.19 12.3 2.7 1.6 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Yip1 PF04893.17 PFH32824.1 - 6.2 6.5 8.8 0.075 12.7 0.6 1.8 2 0 0 2 2 2 0 Yip1 domain SPRY PF00622.28 PFH32825.1 - 0.0099 16.0 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Peptidase_M20 PF01546.28 PFH32826.1 - 6.8e-32 110.9 0.0 1.5e-31 109.7 0.0 1.6 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PFH32826.1 - 3.4e-12 46.2 0.3 7.2e-12 45.2 0.3 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain GMC_oxred_N PF00732.19 PFH32827.1 - 2.2e-21 76.5 0.1 2.3e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 PFH32827.1 - 2.7e-15 57.2 0.4 5.9e-12 46.3 0.0 2.9 3 0 0 3 3 3 2 GMC oxidoreductase TrkA_N PF02254.18 PFH32827.1 - 0.00014 22.1 0.0 0.00049 20.3 0.1 1.9 2 0 0 2 2 2 1 TrkA-N domain DAO PF01266.24 PFH32827.1 - 0.00019 21.1 0.0 0.00039 20.1 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 PFH32827.1 - 0.00054 19.6 0.0 0.0017 18.0 0.0 1.9 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 PFH32827.1 - 0.0056 16.1 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.27 PFH32827.1 - 0.009 16.5 0.0 0.024 15.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 PFH32827.1 - 0.016 15.4 0.2 0.036 14.2 0.2 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 PFH32827.1 - 0.017 14.4 0.1 0.033 13.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PFH32827.1 - 0.02 15.1 0.1 0.055 13.7 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 PFH32827.1 - 0.025 13.9 0.0 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 PFH32827.1 - 0.033 13.3 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 PFH32827.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 PFH32827.1 - 0.035 12.8 0.0 0.056 12.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein XdhC_C PF13478.6 PFH32827.1 - 0.12 12.9 0.0 0.43 11.1 0.0 2.0 1 0 0 1 1 1 0 XdhC Rossmann domain Sacchrp_dh_NADP PF03435.18 PFH32827.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_3 PF13738.6 PFH32827.1 - 0.16 11.2 0.2 1.2 8.3 0.1 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 PFH32827.1 - 0.18 11.7 0.5 0.41 10.5 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 PFH32827.1 - 0.19 12.3 0.0 0.59 10.8 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_C PF05173.14 PFH32829.1 - 4.1e-41 139.8 0.0 5.6e-41 139.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 PFH32829.1 - 3.3e-29 101.5 0.0 6.7e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.16 PFH32829.1 - 0.00021 21.9 0.0 0.00037 21.1 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 PFH32829.1 - 0.0018 18.6 0.0 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 PFH32829.1 - 0.013 15.9 0.1 0.059 13.8 0.2 2.0 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Cas_Cas02710 PF09670.10 PFH32829.1 - 0.037 12.8 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Cpn60_TCP1 PF00118.24 PFH32831.1 - 7.9e-134 447.0 9.1 3.4e-100 336.0 1.3 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family PEX11 PF05648.14 PFH32832.1 - 8.8e-41 139.8 3.2 1.9e-40 138.7 3.2 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) TEX13 PF15186.6 PFH32832.1 - 0.16 11.7 0.7 0.32 10.7 0.7 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Acid_PPase PF12689.7 PFH32833.1 - 0.02 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Acid Phosphatase WD40 PF00400.32 PFH32834.1 - 1.9e-44 148.7 25.8 1.3e-07 32.2 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH32834.1 - 1.1e-17 64.1 0.0 0.0027 17.9 0.0 6.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PFH32834.1 - 0.008 15.2 8.8 16 4.3 0.1 5.3 1 1 3 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Fungal_TACC PF12709.7 PFH32834.1 - 0.0089 16.4 2.3 0.048 14.1 0.8 2.6 1 1 1 2 2 2 1 Fungal Transforming acidic coiled-coil (TACC) proteins Cep57_CLD_2 PF14197.6 PFH32834.1 - 0.42 10.7 6.1 8.7 6.5 0.9 3.1 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Prefoldin_2 PF01920.20 PFH32834.1 - 0.52 10.3 5.1 0.33 10.9 2.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF755 PF05501.11 PFH32834.1 - 0.81 10.0 17.9 2.3 8.5 17.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF755) GREB1 PF15782.5 PFH32834.1 - 3.2 4.8 8.9 4.2 4.4 8.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOGA PF11365.8 PFH32834.1 - 4.7 8.4 12.2 2.3 9.4 1.3 3.4 3 1 1 4 4 3 0 Protein SOGA IMUP PF15761.5 PFH32834.1 - 5 7.9 13.9 15 6.4 13.9 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein FapA PF03961.13 PFH32834.1 - 6.8 5.2 4.9 10 4.6 4.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 PFH32834.1 - 9 6.2 8.6 2.6 7.9 1.2 2.8 1 1 1 2 2 2 0 Septum formation initiator TPR_12 PF13424.6 PFH32835.1 - 0.00051 20.3 0.5 0.15 12.4 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 PFH32835.1 - 0.0022 17.9 0.2 0.0065 16.5 0.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box_4 PF15966.5 PFH32835.1 - 0.021 14.7 0.1 0.039 13.9 0.1 1.3 1 0 0 1 1 1 0 F-box TPR_11 PF13414.6 PFH32835.1 - 0.026 14.2 0.0 0.073 12.8 0.0 1.7 1 0 0 1 1 1 0 TPR repeat TPR_14 PF13428.6 PFH32835.1 - 0.048 14.5 2.1 0.22 12.4 0.3 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4590 PF15257.6 PFH32835.1 - 0.16 11.9 0.3 0.34 10.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) F-box PF00646.33 PFH32835.1 - 0.39 10.7 2.1 0.78 9.7 2.1 1.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 PFH32835.1 - 1.2 9.1 4.8 2.6 8.0 4.8 1.6 1 0 0 1 1 1 0 F-box-like TRAM_LAG1_CLN8 PF03798.16 PFH32836.1 - 9.6e-16 58.1 11.3 9.6e-16 58.1 11.3 1.5 2 0 0 2 2 2 1 TLC domain Cyclin_N PF00134.23 PFH32837.1 - 0.1 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain AMP-binding PF00501.28 PFH32839.1 - 3.8e-79 266.3 0.1 2.7e-78 263.4 0.1 2.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PFH32839.1 - 0.00011 23.1 0.6 0.00036 21.5 0.0 2.3 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4228 PF14009.6 PFH32839.1 - 0.023 15.1 0.1 0.05 14.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Hydrolase_3 PF08282.12 PFH32840.1 - 5.2e-46 157.5 0.0 6.3e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PFH32840.1 - 2.2e-10 40.5 0.0 2.6e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 PFH32840.1 - 0.00038 20.8 0.0 0.33 11.2 0.0 2.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PFH32840.1 - 0.066 13.3 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 PFH32840.1 - 0.11 12.9 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 PFH32840.1 - 0.12 12.5 0.0 0.65 10.1 0.0 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MCM PF00493.23 PFH32841.1 - 6.2e-93 310.0 0.1 9.4e-93 309.4 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PFH32841.1 - 4.6e-26 91.1 0.0 9.7e-26 90.1 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PFH32841.1 - 4e-25 88.1 0.1 8.6e-25 87.0 0.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 PFH32841.1 - 9.2e-08 31.7 0.0 9.8e-06 25.1 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PFH32841.1 - 0.0013 18.7 0.0 0.0045 17.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 PFH32841.1 - 0.0032 17.3 0.0 0.012 15.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 PFH32841.1 - 0.037 13.7 0.0 0.23 11.1 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain Colicin_M PF14859.6 PFH32842.1 - 0.016 14.3 0.1 0.041 13.0 0.0 1.6 2 0 0 2 2 2 0 Colicin M DUF4887 PF16228.5 PFH32842.1 - 0.097 12.8 2.0 0.33 11.1 2.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) ATP-synt_ab_C PF00306.27 PFH32843.1 - 0.036 14.4 0.2 0.044 14.1 0.2 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain DUF2682 PF10909.8 PFH32843.1 - 0.095 13.2 1.0 2.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2682) Band_7 PF01145.25 PFH32844.1 - 1.4e-24 87.1 0.5 2.9e-24 86.1 0.2 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 PFH32844.1 - 1.9e-06 27.2 2.1 2.6e-06 26.7 2.1 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial BMC PF00936.19 PFH32844.1 - 0.019 14.9 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 BMC domain Med2 PF11214.8 PFH32844.1 - 0.023 14.9 0.6 0.042 14.0 0.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 NTF2 PF02136.20 PFH32845.1 - 5.6e-17 62.4 0.2 5.9e-16 59.1 0.1 2.2 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain BLOC1S3 PF15753.5 PFH32848.1 - 0.017 15.3 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 SPATA24 PF15175.6 PFH32848.1 - 0.018 14.9 0.2 0.024 14.5 0.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 TMF_DNA_bd PF12329.8 PFH32848.1 - 0.023 14.7 4.1 0.034 14.2 0.6 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DnaGprimase_HBD PF16730.5 PFH32848.1 - 0.06 13.4 0.0 0.082 13.0 0.0 1.1 1 0 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain MPS2 PF17060.5 PFH32848.1 - 0.071 12.4 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 CENP-H PF05837.12 PFH32848.1 - 0.095 13.1 1.1 0.13 12.7 1.1 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) PKcGMP_CC PF16808.5 PFH32848.1 - 0.16 11.8 1.2 0.36 10.7 1.2 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4226 PF10774.9 PFH32848.1 - 0.18 12.1 4.6 0.31 11.3 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) ATG16 PF08614.11 PFH32848.1 - 0.86 9.8 8.5 1.8 8.8 8.5 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 PFH32848.1 - 1.1 9.0 5.1 6.1 6.7 1.7 2.1 1 1 1 2 2 2 0 Septum formation initiator NIF PF03031.18 PFH32849.1 - 1.8e-40 138.2 0.0 2.4e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DEAD PF00270.29 PFH32851.1 - 5.4e-44 150.0 0.0 1.1e-43 149.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH32851.1 - 5.9e-18 65.2 0.1 3.4e-10 40.3 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DUF4217 PF13959.6 PFH32851.1 - 1.5e-09 37.9 0.3 4.5e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PFH32851.1 - 1.2e-07 31.9 0.3 5.2e-07 29.8 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PFH32851.1 - 0.25 11.6 1.6 0.7 10.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain PRIMA1 PF16101.5 PFH32852.1 - 4.6 7.3 6.6 0.34 11.0 1.2 1.9 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 Vac14_Fig4_bd PF11916.8 PFH32853.1 - 2.9e-39 134.6 5.4 1e-35 123.0 5.4 2.3 2 0 0 2 2 2 2 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 PFH32854.1 - 2.5e-36 124.1 0.0 5.5e-34 116.7 0.0 2.9 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 PFH32854.1 - 4.2e-07 29.7 13.1 0.00019 21.4 0.0 5.4 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 PFH32854.1 - 1.1e-06 29.0 0.5 0.00011 22.6 0.0 3.2 2 1 1 3 3 3 1 HEAT-like repeat Tti2 PF10521.9 PFH32854.1 - 0.00026 20.6 0.4 0.039 13.5 0.0 2.8 2 1 1 3 3 3 1 Tti2 family CLASP_N PF12348.8 PFH32854.1 - 0.0027 17.3 0.0 0.26 10.8 0.1 2.7 2 1 1 3 3 3 2 CLASP N terminal Ecm29 PF13001.7 PFH32854.1 - 0.097 11.3 0.4 9 4.8 0.0 2.2 2 0 0 2 2 2 0 Proteasome stabiliser HEAT_2 PF13646.6 PFH32854.1 - 0.36 11.3 5.9 1.9 9.0 0.0 3.8 4 1 1 5 5 5 0 HEAT repeats PPR_2 PF13041.6 PFH32855.1 - 6.2e-07 29.5 0.0 0.0078 16.4 0.0 4.7 6 0 0 6 6 6 1 PPR repeat family PPR PF01535.20 PFH32855.1 - 7.6e-06 25.8 1.5 0.41 11.0 0.0 5.6 6 0 0 6 6 6 1 PPR repeat PPR_3 PF13812.6 PFH32855.1 - 0.0001 22.3 0.0 0.087 12.9 0.0 4.5 5 1 1 6 6 6 1 Pentatricopeptide repeat domain PPR_long PF17177.4 PFH32855.1 - 0.022 14.1 1.1 0.93 8.8 0.0 2.8 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP TPR_12 PF13424.6 PFH32855.1 - 0.4 11.0 14.2 0.037 14.3 1.9 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 PFH32855.1 - 2.5 8.0 6.1 0.35 10.8 0.5 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 PFH32856.1 - 1.2e-13 51.5 0.0 2.7e-06 27.9 0.0 3.5 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PFH32856.1 - 1.7e-12 46.3 0.0 0.11 13.1 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 PFH32856.1 - 5.4e-10 39.6 0.0 4.1e-05 24.0 0.0 4.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 PFH32856.1 - 5.9e-07 29.7 0.1 0.76 10.3 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 PFH32856.1 - 0.00017 21.8 0.0 11 6.4 0.0 3.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Nop PF01798.18 PFH32859.1 - 3.2e-62 210.0 0.0 5e-62 209.4 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 PFH32859.1 - 6.4e-34 117.5 5.5 6.4e-34 117.5 5.5 1.7 2 0 0 2 2 2 1 Prp31 C terminal domain LcrG PF07216.12 PFH32859.1 - 0.23 11.4 0.1 0.23 11.4 0.1 2.1 2 0 0 2 2 2 0 LcrG protein NAP PF00956.18 PFH32860.1 - 1.4e-68 231.0 11.2 2.2e-67 227.1 11.2 2.1 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Gp-FAR-1 PF05823.12 PFH32860.1 - 0.00058 20.2 0.1 0.0013 19.1 0.1 1.6 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SKA2 PF16740.5 PFH32860.1 - 0.005 16.6 0.9 0.012 15.3 0.9 1.6 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 CENP-Q PF13094.6 PFH32860.1 - 2.2 8.5 8.7 2.7 8.2 1.9 2.7 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-CW PF07496.15 PFH32861.1 - 6e-09 35.8 7.1 1.2e-08 34.8 7.1 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger Methyltransf_24 PF13578.6 PFH32861.1 - 0.025 15.6 0.1 0.11 13.5 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 PFH32861.1 - 0.029 13.7 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RuvX PF03652.15 PFH32864.1 - 1.1e-05 25.9 0.0 0.00088 19.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction resolvase AAA_16 PF13191.6 PFH32865.1 - 0.014 15.8 0.3 0.046 14.1 0.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 PFH32865.1 - 0.018 15.5 0.1 0.1 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 PFH32865.1 - 0.024 14.4 0.0 0.032 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PFH32865.1 - 0.03 13.7 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 PFH32865.1 - 0.041 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 PFH32865.1 - 0.043 13.4 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PRK PF00485.18 PFH32865.1 - 0.054 13.2 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_35 PF14516.6 PFH32865.1 - 0.085 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain KAP_NTPase PF07693.14 PFH32865.1 - 0.14 11.4 0.0 3 7.0 0.0 2.1 1 1 0 1 1 1 0 KAP family P-loop domain AAA_28 PF13521.6 PFH32865.1 - 0.16 12.2 0.0 7 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAAG1 PF15354.6 PFH32865.1 - 0.24 12.0 1.0 0.47 11.0 0.1 2.0 2 0 0 2 2 2 0 Kidney-associated antigen 1 AAA_15 PF13175.6 PFH32865.1 - 0.25 11.0 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TFIID_20kDa PF03847.13 PFH32866.1 - 0.0069 16.9 0.0 0.011 16.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 PFH32866.1 - 0.02 15.1 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PFH32866.1 - 0.31 11.4 0.9 1.9 8.8 0.0 2.5 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 CARMIL_C PF16000.5 PFH32866.1 - 0.42 10.2 3.7 0.66 9.6 3.7 1.3 1 0 0 1 1 1 0 CARMIL C-terminus EGF PF00008.27 PFH32868.1 - 5.5e-08 33.0 134.9 0.00017 21.8 8.2 12.4 11 2 0 11 11 11 7 EGF-like domain Collagen PF01391.18 PFH32868.1 - 1.3e-05 24.8 18.3 3.4e-05 23.5 18.3 1.6 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) EGF_3 PF12947.7 PFH32868.1 - 4.3e-05 23.6 34.1 0.00015 21.9 11.3 11.0 10 0 0 10 10 10 4 EGF domain EGF_MSP1_1 PF12946.7 PFH32868.1 - 0.011 15.7 4.9 0.011 15.7 4.9 10.2 9 1 0 9 9 9 0 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 PFH32868.1 - 0.016 15.5 1.3 0.016 15.5 1.3 11.1 10 2 0 10 10 10 0 Pvs28 EGF domain cEGF PF12662.7 PFH32868.1 - 0.019 14.9 3.9 0.019 14.9 3.9 10.7 10 1 0 10 10 10 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PFH32868.1 - 0.02 15.2 4.6 0.02 15.2 4.6 11.3 8 2 3 11 11 11 0 Coagulation Factor Xa inhibitory site Transket_pyr PF02779.24 PFH32870.1 - 1.6e-60 203.8 0.0 2.7e-60 203.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 PFH32870.1 - 6.9e-55 186.1 0.0 1e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 PFH32870.1 - 1.5e-46 157.8 0.0 2.6e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 PFH32870.1 - 2.4e-18 65.4 0.4 5.2e-18 64.3 0.4 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus DUF226 PF02890.14 PFH32870.1 - 0.1 12.6 0.2 0.28 11.2 0.1 1.7 1 1 1 2 2 2 0 Borrelia family of unknown function DUF226 Plus-3 PF03126.18 PFH32871.1 - 4.8e-16 59.2 0.0 2.7e-15 56.8 0.0 2.1 2 0 0 2 2 2 1 Plus-3 domain Sporozoite_P67 PF05642.11 PFH32871.1 - 0.27 9.3 8.9 0.57 8.2 8.9 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NPV_P10 PF05531.12 PFH32871.1 - 0.29 11.6 1.4 17 5.9 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Rhomboid PF01694.22 PFH32872.1 - 0.0022 18.0 0.8 0.23 11.5 0.1 2.8 2 0 0 2 2 2 2 Rhomboid family MTS PF05175.14 PFH32873.1 - 0.0067 16.0 0.1 1.3 8.5 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase small domain DUF713 PF05218.14 PFH32875.1 - 0.046 13.4 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF713) DUF148 PF02520.17 PFH32875.1 - 0.051 13.7 0.1 0.25 11.4 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF148 ABC2_membrane PF01061.24 PFH32876.1 - 1.3e-24 86.8 22.5 1.7e-24 86.4 22.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PFH32876.1 - 4.4e-22 79.1 0.0 6.5e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PFH32876.1 - 9.5e-05 21.7 14.3 9.5e-05 21.7 14.3 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 PFH32876.1 - 0.002 17.8 0.2 0.0054 16.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 PFH32876.1 - 0.0039 17.6 0.0 0.0083 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 PFH32876.1 - 0.0054 16.3 0.0 0.059 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PFH32876.1 - 0.025 14.8 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PFH32876.1 - 0.031 14.8 0.0 0.051 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 PFH32876.1 - 0.041 13.8 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 PFH32876.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 PFH32876.1 - 0.065 13.7 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 PFH32876.1 - 0.071 12.9 0.2 0.29 10.9 0.1 1.7 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 PFH32876.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PFH32876.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 PFH32876.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 PFH32876.1 - 0.16 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RecA PF00154.21 PFH32876.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Adaptin_N PF01602.20 PFH32878.1 - 5.6e-75 252.9 6.6 7e-70 236.1 7.2 2.5 2 1 0 2 2 2 2 Adaptin N terminal region AP4E_app_platf PF14807.6 PFH32878.1 - 1.2e-16 60.9 0.0 2.8e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Cnd1 PF12717.7 PFH32878.1 - 1.5e-10 41.3 0.3 3.1e-05 24.1 0.0 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PFH32878.1 - 4.7e-05 23.8 3.1 0.078 13.5 0.3 4.1 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 PFH32878.1 - 0.0046 17.3 7.4 0.22 11.9 0.2 4.8 5 0 0 5 5 5 1 HEAT repeats ParcG PF10274.9 PFH32878.1 - 0.041 14.0 4.5 2.6 8.2 0.0 3.7 4 0 0 4 4 4 0 Parkin co-regulated protein HEAT PF02985.22 PFH32878.1 - 0.045 14.0 3.2 0.46 10.9 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat ANTH PF07651.16 PFH32878.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 ANTH domain 7TMR-HDED PF07697.11 PFH32878.1 - 0.21 11.7 0.4 0.42 10.7 0.0 1.6 2 0 0 2 2 2 0 7TM-HD extracellular PRIMA1 PF16101.5 PFH32878.1 - 3.6 7.6 11.0 0.073 13.1 2.2 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Lactococcin_972 PF09683.10 PFH32879.1 - 1.6 9.4 5.1 1.2 9.7 0.7 2.4 1 1 1 2 2 2 0 Bacteriocin (Lactococcin_972) MMR_HSR1_Xtn PF16897.5 PFH32881.1 - 1.8e-44 150.1 0.6 3e-44 149.4 0.6 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 PFH32881.1 - 2.4e-21 75.9 0.0 5.4e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 PFH32881.1 - 1.3e-20 73.2 0.1 2.5e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 PFH32881.1 - 1.8e-11 43.8 0.1 5.2e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PFH32881.1 - 5.5e-05 23.3 0.2 0.39 10.8 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 PFH32881.1 - 0.00022 20.3 0.3 0.0024 16.9 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 PFH32881.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.27 PFH32881.1 - 0.053 13.0 0.2 15 5.0 0.0 3.4 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PFH32881.1 - 0.086 12.7 1.7 0.55 10.1 0.1 2.7 2 1 1 3 3 3 0 RsgA GTPase SRPRB PF09439.10 PFH32881.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ribosomal_L24e PF01246.20 PFH32882.1 - 8e-27 93.3 0.6 8e-27 93.3 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 PFH32882.1 - 0.0053 16.3 1.1 0.0064 16.1 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF3395 PF11875.8 PFH32884.1 - 2.4e-27 95.8 0.1 4.9e-27 94.7 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 PFH32884.1 - 4.2e-18 65.2 0.2 1e-17 64.0 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain OHA PF14418.6 PFH32885.1 - 3.6e-21 74.8 0.0 9.5e-21 73.4 0.0 1.6 2 0 0 2 2 2 1 OST-HTH Associated domain SNARE_assoc PF09335.11 PFH32886.1 - 1.9e-08 34.8 3.1 1.9e-08 34.8 3.1 2.7 3 0 0 3 3 3 1 SNARE associated Golgi protein Ctr PF04145.15 PFH32886.1 - 0.015 15.9 0.0 0.1 13.2 0.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family Erg28 PF03694.13 PFH32886.1 - 0.31 11.4 4.1 2.5 8.5 0.4 2.4 2 0 0 2 2 2 0 Erg28 like protein CactinC_cactus PF09732.9 PFH32887.1 - 6.6e-56 187.6 8.0 1.2e-55 186.8 8.0 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 PFH32887.1 - 9.1e-44 149.6 3.2 2.4e-43 148.2 3.2 1.8 1 0 0 1 1 1 1 Conserved mid region of cactin Coatomer_E PF04733.14 PFH32888.1 - 1.4e-22 80.5 1.2 1.1e-10 41.5 0.2 2.0 2 0 0 2 2 2 2 Coatomer epsilon subunit TPR_19 PF14559.6 PFH32888.1 - 0.0053 17.2 5.9 0.013 16.0 0.2 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 PFH32888.1 - 0.28 11.1 6.1 3.4 7.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat T3SSipB PF16535.5 PFH32888.1 - 0.57 10.7 5.5 0.085 13.3 1.0 1.8 2 0 0 2 2 2 0 Type III cell invasion protein SipB TPR_2 PF07719.17 PFH32888.1 - 1.6 9.0 7.5 56 4.2 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DA1-like PF12315.8 PFH32889.1 - 5.6e-14 52.0 0.1 1.3e-13 50.8 0.1 1.5 1 1 0 1 1 1 1 Protein DA1 zf-C4_ClpX PF06689.13 PFH32889.1 - 1.4 8.9 4.5 43 4.1 0.0 3.6 3 0 0 3 3 3 0 ClpX C4-type zinc finger DUF2256 PF10013.9 PFH32889.1 - 6.5 7.0 6.5 2.6 8.2 2.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) CDO_I PF05995.12 PFH32890.1 - 1.8e-17 63.2 0.4 6e-17 61.5 0.6 1.8 2 0 0 2 2 2 1 Cysteine dioxygenase type I Pyridoxal_deC PF00282.19 PFH32890.1 - 2.3e-08 33.2 0.2 6e-08 31.8 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain RRP36 PF06102.12 PFH32891.1 - 8.7e-26 90.8 27.8 1.6e-25 90.0 23.4 2.4 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 TFIIE-A_C PF11521.8 PFH32891.1 - 0.047 14.0 2.5 0.052 13.9 0.2 2.3 2 1 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha PseudoU_synth_2 PF00849.22 PFH32892.1 - 1.6e-05 25.1 0.1 0.00045 20.3 0.1 2.3 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 PFH32892.1 - 0.0042 16.8 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 S4 domain Nucleoside_tran PF01733.18 PFH32893.1 - 5.2e-15 55.6 10.7 5.2e-15 55.6 10.7 2.7 2 2 0 2 2 2 1 Nucleoside transporter La PF05383.17 PFH32894.1 - 0.025 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 La domain Tox-PL-2 PF15643.6 PFH32894.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Papain fold toxin 2 DUF1116 PF06545.11 PFH32895.1 - 0.21 11.0 1.9 0.72 9.3 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1116) Peptidase_M16_M PF16187.5 PFH32896.1 - 5e-64 216.3 0.0 1.1e-63 215.2 0.0 1.6 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 PFH32896.1 - 7.6e-38 129.8 0.0 2.1e-37 128.4 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PFH32896.1 - 9.6e-27 94.2 0.1 1.1e-16 61.4 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain TTL PF03133.15 PFH32897.1 - 1e-52 179.1 0.5 1.7e-52 178.4 0.5 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PFH32897.1 - 6.1e-09 35.5 0.1 0.00011 21.6 0.0 3.3 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PFH32897.1 - 8.1e-05 22.0 0.0 0.097 11.9 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Glycos_transf_4 PF00953.21 PFH32899.1 - 1.6e-36 125.7 10.9 1.6e-26 93.2 4.5 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 4 Mito_carr PF00153.27 PFH32901.1 - 5.1e-10 39.1 0.1 4.8e-06 26.4 0.1 3.5 4 0 0 4 4 4 2 Mitochondrial carrier protein CAF-1_p60_C PF15512.6 PFH32901.1 - 0.039 14.4 0.2 0.039 14.4 0.2 1.6 2 0 0 2 2 2 0 Chromatin assembly factor complex 1 subunit p60, C-terminal HSP90 PF00183.18 PFH32903.1 - 8.6e-187 622.1 38.8 8.6e-187 622.1 38.8 2.2 2 1 1 3 3 3 1 Hsp90 protein HATPase_c PF02518.26 PFH32903.1 - 9.7e-13 48.6 0.1 2e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PFH32903.1 - 2.8e-11 43.4 0.1 2.8e-11 43.4 0.1 2.8 2 1 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L1 PF00687.21 PFH32906.1 - 1.7e-24 86.7 0.0 5e-23 81.9 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L1p/L10e family AAA PF00004.29 PFH32907.1 - 2.4e-37 128.3 0.0 5.2e-37 127.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PFH32907.1 - 1e-13 50.8 0.2 4.6e-13 48.8 0.2 2.2 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 PFH32907.1 - 3.8e-09 36.4 0.1 1.1e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 PFH32907.1 - 8.6e-06 25.8 0.0 6.7e-05 22.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PFH32907.1 - 4.4e-05 23.8 0.1 0.048 13.9 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 PFH32907.1 - 5e-05 23.5 0.0 9.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 PFH32907.1 - 0.0002 21.8 2.9 0.03 14.7 0.0 3.4 3 1 1 4 4 4 1 AAA ATPase domain AAA_28 PF13521.6 PFH32907.1 - 0.0014 18.9 0.1 0.0036 17.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PFH32907.1 - 0.0017 18.5 1.4 0.025 14.7 1.4 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PFH32907.1 - 0.004 16.9 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 PFH32907.1 - 0.0042 17.1 0.0 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 PFH32907.1 - 0.012 15.4 0.1 0.03 14.0 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 PFH32907.1 - 0.019 14.3 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 PFH32907.1 - 0.024 14.2 0.7 0.72 9.4 0.4 2.7 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 PFH32907.1 - 0.088 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PFH32907.1 - 0.11 13.0 0.5 0.44 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PFH32907.1 - 0.23 11.9 0.0 0.65 10.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase zf-RING_2 PF13639.6 PFH32909.1 - 6.8e-12 45.5 8.3 1e-11 44.9 8.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PFH32909.1 - 4.8e-09 35.9 5.9 7.1e-09 35.4 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PFH32909.1 - 7.8e-09 35.2 6.1 1.2e-08 34.6 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PFH32909.1 - 2.7e-08 33.9 4.3 5e-08 33.1 4.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PFH32909.1 - 7.7e-08 32.1 5.5 1.2e-07 31.5 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH32909.1 - 9.9e-06 25.4 5.4 1.5e-05 24.9 5.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PFH32909.1 - 1.5e-05 24.9 3.3 2.6e-05 24.1 3.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PFH32909.1 - 7.6e-05 22.5 6.1 0.00014 21.6 6.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PFH32909.1 - 0.0051 16.9 5.2 0.01 16.0 5.2 1.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 PFH32909.1 - 0.0077 15.9 3.5 0.012 15.3 3.5 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 PFH32909.1 - 0.0078 16.2 0.7 0.015 15.4 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 PFH32909.1 - 0.02 14.7 4.8 0.034 13.9 4.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DPPIV_rep PF18811.1 PFH32909.1 - 0.066 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) low complexity region zf-RING_10 PF16685.5 PFH32909.1 - 0.16 12.1 5.5 0.28 11.3 5.5 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 PFH32909.1 - 0.26 11.2 3.4 0.46 10.4 3.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 PFH32909.1 - 0.38 10.4 4.3 0.85 9.3 4.3 1.6 1 1 0 1 1 1 0 P-11 zinc finger DUF1272 PF06906.11 PFH32909.1 - 0.53 10.4 5.0 0.96 9.6 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Pkinase PF00069.25 PFH32910.1 - 5e-64 216.2 0.0 5.7e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH32910.1 - 1.9e-40 138.8 0.0 2.2e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH32910.1 - 1.3e-07 31.3 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SmaI PF17411.2 PFH32910.1 - 0.0093 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Type II site-specific deoxyribonuclease Pkinase_fungal PF17667.1 PFH32910.1 - 0.017 13.9 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 PFH32910.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 PFH32910.1 - 0.052 13.1 0.1 0.12 11.9 0.1 1.6 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 PFH32910.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 TruD PF01142.18 PFH32911.1 - 1.2e-45 156.2 0.0 1.8e-12 46.8 0.0 5.8 5 1 0 5 5 5 5 tRNA pseudouridine synthase D (TruD) DUF3883 PF13020.6 PFH32912.1 - 8.2e-14 51.4 0.0 1.4e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) eIF-5_eIF-2B PF01873.17 PFH32913.1 - 8.7e-36 122.3 0.0 2.4e-35 120.9 0.0 1.8 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 PFH32913.1 - 2.4e-13 50.0 0.3 2.4e-13 50.0 0.3 2.9 3 0 0 3 3 1 1 eIF4-gamma/eIF5/eIF2-epsilon CDC45 PF02724.14 PFH32913.1 - 0.002 16.5 11.3 0.0025 16.2 11.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 PFH32913.1 - 0.088 11.0 22.8 0.12 10.6 22.8 1.1 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.6 PFH32913.1 - 0.11 11.3 9.6 0.14 10.8 9.6 1.1 1 0 0 1 1 1 0 Raftlin eIF-3c_N PF05470.12 PFH32913.1 - 0.17 10.2 14.0 0.23 9.7 14.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Menin PF05053.13 PFH32913.1 - 0.39 9.0 8.2 0.51 8.6 8.2 1.1 1 0 0 1 1 1 0 Menin DUF4604 PF15377.6 PFH32913.1 - 0.45 10.9 29.3 0.9 9.9 29.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SLC12 PF03522.15 PFH32913.1 - 0.81 8.6 14.1 1.1 8.2 14.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 PFH32913.1 - 0.9 8.3 7.2 1.4 7.7 7.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 PFH32913.1 - 1.3 9.0 6.0 2.2 8.3 6.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 PFH32913.1 - 3.1 7.6 19.2 7.5 6.3 19.2 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 PFH32913.1 - 3.6 7.5 17.2 6 6.8 17.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF4407 PF14362.6 PFH32913.1 - 6.3 6.0 7.5 8.8 5.6 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 PFH32913.1 - 8.6 5.0 16.4 12 4.6 16.4 1.1 1 0 0 1 1 1 0 Presenilin TMEM247 PF15444.6 PFH32913.1 - 8.6 6.3 8.7 13 5.7 8.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 DUF45 PF01863.17 PFH32914.1 - 5.3e-05 23.4 0.2 9.6e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.10 PFH32914.1 - 0.00096 19.3 0.1 0.00096 19.3 0.1 3.1 3 0 0 3 3 3 1 WLM domain A_deamin PF02137.18 PFH32916.1 - 1.3e-29 103.7 0.4 1.8e-20 73.7 0.0 4.7 5 1 0 5 5 5 3 Adenosine-deaminase (editase) domain NAD_kinase PF01513.21 PFH32918.1 - 8.9e-62 208.9 0.0 1.7e-61 208.0 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 PFH32918.1 - 0.0038 16.8 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PPP1R35_C PF15503.6 PFH32919.1 - 0.05 13.4 0.9 0.15 11.8 0.9 1.8 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Heme_oxygenase PF01126.20 PFH32919.1 - 0.14 11.9 0.2 0.28 11.0 0.2 1.4 1 0 0 1 1 1 0 Heme oxygenase DUF4795 PF16043.5 PFH32919.1 - 0.17 11.4 5.0 5.4 6.6 5.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) IQ PF00612.27 PFH32921.1 - 0.00039 20.0 20.7 0.02 14.7 0.2 4.0 4 0 0 4 4 4 3 IQ calmodulin-binding motif BUD22 PF09073.10 PFH32922.1 - 1.8e-05 24.3 13.2 1.8e-05 24.3 13.2 1.1 1 0 0 1 1 1 1 BUD22 zf-CCHC_3 PF13917.6 PFH32922.1 - 2.1e-05 24.4 0.1 4.2e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle SR-25 PF10500.9 PFH32922.1 - 0.00016 21.3 28.9 0.00022 20.9 28.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein zf-CCHC_5 PF14787.6 PFH32922.1 - 0.0063 16.2 0.9 0.014 15.0 0.9 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 PFH32922.1 - 0.013 15.5 1.7 0.022 14.8 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle FYDLN_acid PF09538.10 PFH32922.1 - 0.029 15.0 2.9 0.029 15.0 2.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF4604 PF15377.6 PFH32922.1 - 0.064 13.7 19.2 0.098 13.1 19.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Macoilin PF09726.9 PFH32922.1 - 0.16 10.5 8.5 0.18 10.3 8.5 1.1 1 0 0 1 1 1 0 Macoilin family Smg8_Smg9 PF10220.9 PFH32922.1 - 1.5 7.0 9.6 1.8 6.8 9.6 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Presenilin PF01080.17 PFH32922.1 - 1.7 7.3 12.2 2 7.1 12.2 1.1 1 0 0 1 1 1 0 Presenilin MRI PF15325.6 PFH32922.1 - 1.8 9.7 12.0 0.97 10.6 7.7 2.3 2 0 0 2 2 2 0 Modulator of retrovirus infection SAPS PF04499.15 PFH32922.1 - 2.2 7.0 7.0 2.5 6.8 7.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 PFH32922.1 - 3.7 7.3 12.6 4.8 6.9 12.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.9 PFH32922.1 - 6.6 5.5 14.6 8.2 5.2 14.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RP-C_C PF11800.8 PFH32922.1 - 8 6.5 12.8 21 5.1 8.0 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region GMC_oxred_C PF05199.13 PFH32923.1 - 2.1e-24 86.7 0.0 7.2e-19 68.7 0.0 2.5 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_N PF00732.19 PFH32923.1 - 1.3e-13 51.1 0.3 1.6e-05 24.4 0.0 3.0 3 0 0 3 3 3 2 GMC oxidoreductase SLS PF14611.6 PFH32923.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Pyr_redox_2 PF07992.14 PFH32923.1 - 0.095 11.9 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PFH32923.1 - 0.17 12.1 0.0 0.48 10.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain PH PF00169.29 PFH32924.1 - 0.019 15.5 0.1 0.18 12.4 0.1 2.2 1 1 0 1 1 1 0 PH domain Sec3-PIP2_bind PF15277.6 PFH32924.1 - 0.022 14.9 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH_6 PF15406.6 PFH32924.1 - 0.027 14.8 1.7 0.06 13.6 0.0 2.4 3 0 0 3 3 3 0 Pleckstrin homology domain Mito_carr PF00153.27 PFH32924.1 - 0.19 11.7 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial carrier protein ADH_zinc_N PF00107.26 PFH32925.1 - 4.7e-23 81.6 0.0 7.5e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PFH32925.1 - 1.8e-17 64.6 0.1 5e-17 63.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PFH32925.1 - 1.3e-07 31.4 0.0 6.8e-06 25.9 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain RNA_pol_Rpb1_5 PF04998.17 PFH32926.1 - 3.3e-78 262.8 0.0 7.6e-78 261.6 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 PFH32926.1 - 1.1e-52 178.6 0.3 5.3e-35 121.1 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 PFH32926.1 - 3.3e-25 88.8 0.0 6.2e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 PFH32926.1 - 2.2e-19 69.4 0.1 6.7e-19 67.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 PFH32926.1 - 4.5e-14 52.5 0.0 1.1e-12 48.0 0.0 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 BUD22 PF09073.10 PFH32926.1 - 1.1e-05 25.0 24.4 1.1e-05 25.0 24.4 4.1 4 0 0 4 4 4 1 BUD22 Musclin PF11037.8 PFH32926.1 - 0.094 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Cyclin PF08613.11 PFH32927.1 - 2.3e-13 50.8 0.1 1.4e-07 32.1 0.0 2.4 2 0 0 2 2 2 2 Cyclin Cyclin_N PF00134.23 PFH32927.1 - 0.0096 15.7 0.2 1.8 8.3 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Dynein_light PF01221.18 PFH32928.1 - 7.6e-24 83.8 0.0 9.8e-24 83.5 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 zf-MIZ PF02891.20 PFH32929.1 - 2.2e-10 40.1 2.4 6e-10 38.7 2.4 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Pro_isomerase PF00160.21 PFH32930.1 - 5.7e-41 140.4 0.0 7.3e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L23 PF00276.20 PFH32931.1 - 5.3e-15 55.6 1.1 5.3e-15 55.6 1.1 2.6 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 PFH32931.1 - 9.3e-08 32.2 12.5 3.3e-07 30.4 12.5 2.0 1 1 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Thioredoxin PF00085.20 PFH32933.1 - 1.2e-72 240.4 0.3 1.8e-24 85.7 0.0 3.1 3 0 0 3 3 3 3 Thioredoxin OST3_OST6 PF04756.13 PFH32933.1 - 3.8e-20 72.4 0.0 1.1e-05 24.9 0.0 3.0 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 PFH32933.1 - 4.6e-17 62.0 1.1 2.9e-05 24.2 0.0 3.2 3 0 0 3 3 3 3 Thioredoxin-like Thioredoxin_2 PF13098.6 PFH32933.1 - 2.4e-11 44.0 0.6 0.02 15.4 0.0 4.0 3 2 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PFH32933.1 - 2.1e-07 31.2 0.2 0.97 9.8 0.0 3.8 3 1 1 4 4 4 3 Thioredoxin-like Thioredoxin_6 PF13848.6 PFH32933.1 - 2.1e-07 31.0 0.0 0.01 15.8 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like domain TraF PF13728.6 PFH32933.1 - 9.6e-06 25.6 0.0 4.4 7.1 0.0 3.9 3 1 0 3 3 3 3 F plasmid transfer operon protein ERp29_N PF07912.13 PFH32933.1 - 0.00043 20.4 0.1 0.087 13.0 0.0 3.4 3 1 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_9 PF14595.6 PFH32933.1 - 0.00062 19.6 0.0 15 5.3 0.0 3.4 3 0 0 3 3 3 0 Thioredoxin Mu-like_Com PF10122.9 PFH32933.1 - 0.0034 16.8 0.8 10 5.6 0.0 3.3 3 0 0 3 3 3 1 Mu-like prophage protein Com zf_C2H2_ZHX PF18387.1 PFH32933.1 - 0.0074 15.9 5.0 5.7 6.7 0.0 3.8 5 0 0 5 5 5 2 Zinc-fingers and homeoboxes C2H2 finger domain DNA_alkylation PF08713.11 PFH32933.1 - 0.011 15.5 0.0 4.8 6.8 0.0 2.3 2 0 0 2 2 2 0 DNA alkylation repair enzyme BTHB PF18410.1 PFH32933.1 - 0.014 15.2 0.7 37 4.2 0.0 4.5 4 2 2 6 6 6 0 Basic tilted helix bundle domain NIBRIN_BRCT_II PF16508.5 PFH32933.1 - 0.025 14.9 0.0 8.3 6.8 0.0 3.1 3 0 0 3 3 3 0 Second BRCT domain on Nijmegen syndrome breakage protein DUF953 PF06110.11 PFH32933.1 - 0.053 13.1 0.6 25 4.5 0.0 3.2 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF953) MIT_LIKE_ACTX PF17556.2 PFH32933.1 - 0.065 13.8 0.1 74 4.0 0.0 3.1 3 0 0 3 3 3 0 MIT-like atracotoxin family DDE_Tnp_2 PF04693.12 PFH32933.1 - 0.12 11.6 0.0 9.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Archaeal putative transposase ISC1217 Glyco_transf_90 PF05686.12 PFH32934.1 - 7.1e-71 239.2 0.0 1e-70 238.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Thioredoxin PF00085.20 PFH32934.1 - 3.9e-26 91.0 0.1 3.6e-21 75.1 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin OST3_OST6 PF04756.13 PFH32934.1 - 1.4e-06 27.9 0.1 0.0012 18.3 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Glyco_trans_1_2 PF13524.6 PFH32934.1 - 0.00013 22.3 0.0 0.00043 20.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Thioredoxin_8 PF13905.6 PFH32934.1 - 0.17 12.3 0.1 3.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like SNase PF00565.17 PFH32935.1 - 2e-60 202.0 2.9 1.7e-16 60.7 0.0 5.9 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 PFH32935.1 - 5e-18 65.3 0.0 1.1e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 Tudor domain EF-hand_7 PF13499.6 PFH32936.1 - 2e-15 57.0 0.1 3.6e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PFH32936.1 - 6.9e-13 48.2 0.9 6.1e-06 26.0 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PFH32936.1 - 2.4e-10 39.5 1.0 0.017 15.0 0.1 3.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 PFH32936.1 - 4.1e-08 32.2 0.2 0.057 13.0 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 PFH32936.1 - 9.6e-08 31.2 4.8 0.037 13.5 0.1 3.4 3 0 0 3 3 3 3 EF hand VCBS PF13517.6 PFH32936.1 - 0.11 13.1 0.1 15 6.3 0.0 3.0 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Glutaredoxin PF00462.24 PFH32937.1 - 7e-14 51.8 0.0 2e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 PFH32937.1 - 2.2e-05 24.4 0.0 4.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 PFH32937.1 - 0.00031 20.7 0.0 0.0032 17.4 0.0 2.3 1 1 1 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 PFH32937.1 - 0.046 14.2 0.0 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain zf-HIT PF04438.16 PFH32939.1 - 0.039 13.8 7.2 0.059 13.3 7.2 1.3 1 0 0 1 1 1 0 HIT zinc finger VATC PF18716.1 PFH32939.1 - 2.9 7.8 8.7 0.7 9.8 4.9 1.9 2 0 0 2 2 2 0 Vms1-associating treble clef domain EMP24_GP25L PF01105.24 PFH32940.1 - 2.4e-40 138.4 0.1 2.9e-40 138.2 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Orf78 PF06024.12 PFH32940.1 - 0.025 14.9 0.1 0.057 13.7 0.1 1.5 2 0 0 2 2 2 0 Orf78 (ac78) DUF2721 PF11026.8 PFH32940.1 - 0.26 11.2 2.6 0.33 10.8 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Rep_fac-A_3 PF08661.11 PFH32941.1 - 2.3e-09 37.6 0.0 3e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 HXXEE PF13787.6 PFH32942.1 - 2.1e-13 51.1 1.1 2.1e-13 51.1 1.1 2.9 3 0 0 3 3 3 2 Protein of unknown function with HXXEE motif DUF2070 PF09843.9 PFH32942.1 - 5.5 5.2 9.0 8.2 4.6 9.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ANAPC4_WD40 PF12894.7 PFH32943.1 - 0.059 13.7 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain AcrZ PF10766.9 PFH32944.1 - 0.0075 15.8 0.1 0.028 14.0 0.1 2.0 1 0 0 1 1 1 1 Multidrug efflux pump-associated protein AcrZ PgpA PF04608.13 PFH32944.1 - 2 8.4 13.0 0.021 14.9 2.2 2.9 2 1 1 3 3 3 0 Phosphatidylglycerophosphatase A MF_alpha_N PF05436.11 PFH32945.1 - 0.00085 19.2 0.4 0.0052 16.7 0.1 2.3 2 0 0 2 2 2 1 Mating factor alpha precursor N-terminus PrgI PF12666.7 PFH32945.1 - 0.0023 18.6 1.4 0.0023 18.6 1.4 4.0 3 1 0 3 3 3 1 PrgI family protein CarboxypepD_reg PF13620.6 PFH32947.1 - 8.9e-18 64.4 11.7 0.0003 21.0 0.1 10.5 9 2 0 10 10 10 4 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 PFH32947.1 - 4.4e-05 23.4 0.0 4.8 7.2 0.0 5.2 5 0 0 5 5 5 2 CarboxypepD_reg-like domain DUF2012 PF09430.10 PFH32947.1 - 0.018 15.2 0.0 15 5.7 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2012) SdrD_B PF17210.3 PFH32947.1 - 0.069 13.4 0.0 8.5 6.7 0.0 3.9 4 0 0 4 4 4 0 SdrD B-like domain RPN7 PF10602.9 PFH32948.1 - 6.7e-53 178.9 0.4 9.6e-53 178.4 0.4 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 PFH32948.1 - 1.3e-13 51.3 0.0 5.2e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 PCI domain PknG_TPR PF16918.5 PFH32948.1 - 0.0012 17.7 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_14 PF13428.6 PFH32948.1 - 0.0087 16.8 0.5 6.4 7.9 0.2 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 PFH32948.1 - 0.019 15.0 0.1 0.23 11.6 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 PFH32948.1 - 5.7 7.3 7.9 1 9.6 0.6 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat RNA_pol_A_bac PF01000.26 PFH32949.1 - 2.6e-25 89.0 0.0 1.1e-24 86.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 PFH32949.1 - 5.2e-21 73.9 0.0 7.7e-21 73.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ETF_QO PF05187.13 PFH32949.1 - 0.00057 20.0 0.1 0.00057 20.0 0.1 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Abhydrolase_3 PF07859.13 PFH32950.1 - 2.8e-35 122.1 0.0 4.9e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 PFH32950.1 - 4.7e-06 25.7 0.0 9.4e-06 24.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 PFH32950.1 - 0.045 12.4 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 PFH32950.1 - 0.1 12.1 0.0 0.38 10.2 0.1 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 PFH32950.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase cEGF PF12662.7 PFH32951.1 - 0.031 14.2 1.1 0.031 14.2 1.1 5.0 5 0 0 5 5 5 0 Complement Clr-like EGF-like EGF PF00008.27 PFH32951.1 - 0.041 14.2 10.8 0.041 14.2 10.8 5.8 5 0 0 5 5 5 0 EGF-like domain EGF PF00008.27 PFH32952.1 - 0.12 12.7 50.1 0.37 11.1 3.9 6.2 4 2 0 5 5 5 0 EGF-like domain cEGF PF12662.7 PFH32952.1 - 7 6.7 23.2 1.6 8.8 0.4 5.5 5 0 0 5 5 5 0 Complement Clr-like EGF-like DBR1 PF05011.13 PFH32953.1 - 5.7e-17 62.4 0.0 2e-16 60.7 0.0 1.9 3 0 0 3 3 3 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 PFH32953.1 - 9.6e-06 26.2 0.1 1.5e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PFH32953.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Bystin PF05291.11 PFH32954.1 - 6.5e-114 380.1 0.3 9e-114 379.7 0.3 1.2 1 0 0 1 1 1 1 Bystin Phage_holin_5_1 PF06946.11 PFH32954.1 - 0.12 12.8 0.2 0.35 11.3 0.2 1.8 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 RRP7 PF12923.7 PFH32954.1 - 0.29 11.3 5.0 0.1 12.7 1.9 1.9 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Nop14 PF04147.12 PFH32954.1 - 6.1 4.9 10.6 8.5 4.5 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L36e PF01158.18 PFH32955.1 - 1.1e-36 125.0 1.6 1.3e-36 124.7 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Peptidase_S30 PF01577.16 PFH32955.1 - 0.012 15.3 0.4 0.015 15.0 0.4 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease CLTH PF10607.9 PFH32955.1 - 0.14 12.1 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Syja_N PF02383.18 PFH32959.1 - 7.5e-57 193.1 0.0 2.6e-56 191.3 0.0 1.8 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 PFH32959.1 - 2.9e-10 40.1 0.0 8.4e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family U1snRNP70_N PF12220.8 PFH32961.1 - 0.74 10.5 6.2 2.3 8.9 6.2 2.0 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal OCRE PF17780.1 PFH32963.1 - 0.00015 21.8 3.9 0.00029 20.8 3.9 1.5 1 0 0 1 1 1 1 OCRE domain Rad50_zn_hook PF04423.14 PFH32963.1 - 1 9.3 6.7 0.054 13.3 0.8 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF4407 PF14362.6 PFH32963.1 - 2.3 7.5 10.2 4.4 6.6 10.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAG PF04092.13 PFH32964.1 - 6.5e-08 33.4 1.3 9.6e-08 32.9 1.3 1.2 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH32965.1 - 6.6e-05 23.7 0.1 0.00022 22.0 0.1 1.8 1 1 0 1 1 1 1 SRS domain DUF2574 PF10836.8 PFH32965.1 - 0.44 10.5 2.8 7.1 6.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) SAG PF04092.13 PFH32966.1 - 1.4e-11 45.3 13.3 8.6e-06 26.6 8.8 2.4 2 0 0 2 2 2 2 SRS domain AIRC PF00731.20 PFH32966.1 - 0.037 13.6 1.3 0.062 12.9 0.2 2.0 2 0 0 2 2 2 0 AIR carboxylase DUF4835 PF16119.5 PFH32966.1 - 0.053 12.6 0.0 2.5 7.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4835) TBX PF12598.8 PFH32966.1 - 0.13 13.1 4.1 0.89 10.4 0.1 3.0 2 1 0 2 2 2 0 T-box transcription factor SAG PF04092.13 PFH32967.1 - 1.2e-11 45.6 3.1 1.6e-11 45.1 3.1 1.2 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH32969.1 - 1.9e-09 38.4 6.5 2.7e-09 37.9 6.5 1.2 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH32970.1 - 5e-10 40.3 1.8 7.3e-10 39.7 1.8 1.2 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH32971.1 - 2.6e-12 47.6 5.5 3.6e-12 47.2 5.5 1.2 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH32972.1 - 1.1e-11 45.7 8.0 1.6e-11 45.1 8.0 1.2 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH32973.1 - 3.7e-18 66.6 11.3 1.8e-11 44.9 9.0 2.3 2 0 0 2 2 2 2 SRS domain RRN3 PF05327.11 PFH32977.1 - 2.3e-61 208.0 0.0 2.3e-61 208.0 0.0 3.7 4 1 1 5 5 5 1 RNA polymerase I specific transcription initiation factor RRN3 DUF3223 PF11523.8 PFH32977.1 - 2.1e-12 47.7 0.9 1.9e-10 41.5 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3223) YebO PF13974.6 PFH32978.1 - 7.1 6.8 9.4 1.4e+02 2.7 9.4 3.4 1 0 0 1 1 1 0 YebO-like protein Methyltransf_16 PF10294.9 PFH32981.1 - 0.00062 19.5 0.0 0.098 12.4 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase GDP_Man_Dehyd PF16363.5 PFH32982.1 - 7.8e-149 495.6 0.0 8.8e-149 495.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PFH32982.1 - 6.5e-73 245.1 0.0 7.8e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 PFH32982.1 - 4.8e-07 29.2 0.0 6.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain FA_desaturase PF00487.24 PFH32983.1 - 5.4e-10 39.5 23.0 5.4e-10 39.5 23.0 4.6 3 2 1 5 5 5 2 Fatty acid desaturase EF-hand_7 PF13499.6 PFH32984.1 - 8.1e-07 29.4 0.6 0.013 16.0 0.0 2.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PFH32984.1 - 0.0002 21.0 0.0 0.087 12.8 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 PFH32984.1 - 0.0077 15.7 0.1 0.48 10.1 0.0 3.4 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 PFH32984.1 - 0.009 15.8 0.0 0.44 10.4 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 PFH32984.1 - 0.037 14.3 0.0 4.6 7.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Dickkopf_N PF04706.12 PFH32985.1 - 0.5 10.9 15.9 11 6.6 0.1 3.0 2 1 1 3 3 3 0 Dickkopf N-terminal cysteine-rich region Phage_holin_3_6 PF07332.11 PFH32986.1 - 9.2 6.3 14.3 0.031 14.3 1.9 2.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Ion_trans_2 PF07885.16 PFH32987.1 - 8e-11 41.7 3.5 8e-11 41.7 3.5 1.9 2 0 0 2 2 2 1 Ion channel BK_channel_a PF03493.18 PFH32987.1 - 4.2e-10 39.7 0.0 7.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit ABC_membrane PF00664.23 PFH32988.1 - 3.2e-95 318.9 12.0 7.2e-49 166.9 5.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PFH32988.1 - 4.7e-66 221.5 0.0 3e-32 112.0 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PFH32988.1 - 4.8e-13 49.0 8.2 1.1e-05 24.9 0.1 4.1 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PFH32988.1 - 5.9e-10 39.8 4.9 0.00024 21.5 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 PFH32988.1 - 3.9e-08 33.7 0.2 0.033 14.5 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 PFH32988.1 - 4.6e-08 32.7 0.1 0.0027 17.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PFH32988.1 - 3.2e-07 30.4 0.0 0.025 14.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 PFH32988.1 - 8.8e-07 29.5 0.0 0.099 13.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 PFH32988.1 - 1.2e-06 28.6 0.0 0.0093 15.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 PFH32988.1 - 2.6e-06 26.5 3.6 0.0051 15.7 0.2 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 PFH32988.1 - 3.1e-06 26.9 0.7 0.46 10.0 0.0 4.3 4 0 0 4 4 4 2 AAA domain G-alpha PF00503.20 PFH32988.1 - 5.6e-06 25.7 0.0 0.0087 15.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA PF00004.29 PFH32988.1 - 2.3e-05 24.8 0.3 0.1 13.0 0.1 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PFH32988.1 - 2.9e-05 24.1 0.3 0.28 11.2 0.0 3.4 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 PFH32988.1 - 6e-05 23.0 0.0 0.4 10.4 0.0 3.4 4 0 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 PFH32988.1 - 0.00011 22.5 0.0 0.6 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 PFH32988.1 - 0.00011 22.0 2.8 0.06 13.1 0.3 3.8 3 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 PFH32988.1 - 0.00014 21.2 0.2 0.12 11.6 0.0 2.6 3 0 0 3 3 2 1 Zeta toxin DUF87 PF01935.17 PFH32988.1 - 0.00019 21.6 0.2 0.11 12.6 0.1 3.1 3 1 1 4 4 3 1 Helicase HerA, central domain AAA_7 PF12775.7 PFH32988.1 - 0.0002 20.9 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 PFH32988.1 - 0.0011 19.1 0.1 1.2 9.2 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 PFH32988.1 - 0.0011 19.1 0.0 2.8 8.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 PFH32988.1 - 0.0012 18.1 0.0 1.7 7.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) TniB PF05621.11 PFH32988.1 - 0.0018 17.7 0.1 21 4.5 0.0 3.8 4 0 0 4 4 4 0 Bacterial TniB protein ATP-synt_ab PF00006.25 PFH32988.1 - 0.0019 17.9 0.0 1.6 8.3 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 PFH32988.1 - 0.0021 18.0 2.3 2.3 8.1 0.0 3.5 4 0 0 4 4 4 1 NACHT domain PRK PF00485.18 PFH32988.1 - 0.0024 17.7 0.1 0.36 10.6 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 PFH32988.1 - 0.0027 17.9 5.4 0.28 11.5 1.0 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 PFH32988.1 - 0.0028 17.6 0.0 0.34 10.8 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain APS_kinase PF01583.20 PFH32988.1 - 0.0032 17.4 0.0 0.91 9.4 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.18 PFH32988.1 - 0.0036 16.7 0.2 3.2 7.0 0.2 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_24 PF13479.6 PFH32988.1 - 0.0049 16.6 0.0 2.7 7.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 PFH32988.1 - 0.0059 16.4 0.1 5.9 6.6 0.1 3.2 3 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_17 PF13207.6 PFH32988.1 - 0.0079 16.6 0.3 18 5.8 0.0 3.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 PFH32988.1 - 0.016 15.6 0.0 4.9 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 PFH32988.1 - 0.017 14.4 0.0 6.2 5.9 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain CPT PF07931.12 PFH32988.1 - 0.019 14.8 0.1 0.44 10.4 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.6 PFH32988.1 - 0.021 14.9 0.3 5.3 7.1 0.0 3.4 4 0 0 4 4 3 0 AAA domain CbiA PF01656.23 PFH32988.1 - 0.027 14.5 0.1 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.9 PFH32988.1 - 0.033 14.0 0.2 10 5.9 0.2 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 PFH32988.1 - 0.056 13.2 0.4 5.8 6.6 0.0 3.1 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein TrkA_N PF02254.18 PFH32988.1 - 0.06 13.6 1.4 1.5 9.1 0.0 3.2 3 0 0 3 3 2 0 TrkA-N domain Ploopntkinase3 PF18751.1 PFH32988.1 - 0.067 13.1 0.0 18 5.2 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Mg_chelatase PF01078.21 PFH32988.1 - 0.074 12.4 0.0 10 5.4 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DLIC PF05783.11 PFH32988.1 - 0.079 11.8 2.0 0.14 10.9 0.1 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) MoaE PF02391.17 PFH32988.1 - 0.1 12.9 2.3 2.9 8.2 0.2 2.7 2 0 0 2 2 2 0 MoaE protein TsaE PF02367.17 PFH32988.1 - 0.11 12.6 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 PFH32988.1 - 0.11 13.0 4.2 7 7.1 0.1 2.7 3 0 0 3 3 2 0 AAA domain KAP_NTPase PF07693.14 PFH32988.1 - 0.13 11.5 0.0 14 4.8 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain Peptidase_S78 PF04586.17 PFH32988.1 - 0.15 12.2 0.1 17 5.5 0.0 2.4 2 0 0 2 2 2 0 Caudovirus prohead serine protease MPDZ_u10 PF16667.5 PFH32989.1 - 0.1 13.5 3.3 0.26 12.2 0.2 3.4 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein zf-C2H2_2 PF12756.7 PFH32990.1 - 1.7e-17 63.6 0.4 2.4e-15 56.7 0.1 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 PFH32990.1 - 1.5e-07 31.5 3.0 8.3e-05 22.8 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PFH32990.1 - 2e-06 28.0 6.3 0.00025 21.3 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type RseA_N PF03872.13 PFH32990.1 - 0.04 14.4 0.6 0.11 13.0 0.2 2.0 2 0 0 2 2 2 0 Anti sigma-E protein RseA, N-terminal domain zf-C2H2_4 PF13894.6 PFH32990.1 - 0.12 13.3 5.5 2 9.5 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PFH32990.1 - 2 8.2 8.4 1.6 8.6 0.8 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type FYVE PF01363.21 PFH32990.1 - 5.9 7.1 6.6 42 4.4 0.1 2.7 2 0 0 2 2 2 0 FYVE zinc finger Mito_carr PF00153.27 PFH32991.1 - 3e-60 200.2 0.6 2.8e-22 78.4 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4667 PF15700.5 PFH32991.1 - 0.011 15.9 3.3 0.025 14.7 3.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) SPX PF03105.19 PFH32991.1 - 5.8 6.7 12.6 0.064 13.2 0.2 2.4 2 1 0 2 2 2 0 SPX domain Macoilin PF09726.9 PFH32991.1 - 6.3 5.2 6.0 9.9 4.6 6.0 1.2 1 0 0 1 1 1 0 Macoilin family SAG PF04092.13 PFH32993.1 - 3.5e-13 50.5 13.0 8.5e-10 39.5 2.2 2.9 2 1 0 2 2 2 2 SRS domain SAG PF04092.13 PFH32994.1 - 1.1e-12 48.9 11.3 2.9e-11 44.3 1.6 3.0 2 1 0 2 2 2 2 SRS domain SAG PF04092.13 PFH32995.1 - 2.2e-07 31.7 1.5 0.00013 22.7 0.2 2.5 2 2 0 2 2 2 2 SRS domain SAG PF04092.13 PFH32996.1 - 1.2e-10 42.3 13.7 1.3e-09 38.9 1.7 3.5 2 1 0 2 2 2 2 SRS domain SAG PF04092.13 PFH32997.1 - 9e-12 45.9 0.2 1.6e-08 35.4 0.1 2.4 3 0 0 3 3 3 2 SRS domain SAG PF04092.13 PFH32998.1 - 3.2e-10 40.9 6.2 4.5e-06 27.5 2.0 3.2 3 0 0 3 3 3 3 SRS domain SAG PF04092.13 PFH32999.1 - 6.5e-11 43.1 7.4 1.6e-08 35.4 2.9 3.0 3 0 0 3 3 3 2 SRS domain SAG PF04092.13 PFH33000.1 - 1.6e-09 38.6 17.2 3e-08 34.5 2.1 3.5 3 1 0 3 3 3 2 SRS domain SAG PF04092.13 PFH33001.1 - 1.8e-12 48.2 6.6 1.7e-08 35.3 2.9 3.2 3 0 0 3 3 3 2 SRS domain SAG PF04092.13 PFH33002.1 - 1.8e-13 51.4 2.8 1.6e-08 35.4 2.9 3.1 3 0 0 3 3 3 2 SRS domain SAG PF04092.13 PFH33003.1 - 6.7e-14 52.8 5.9 1.4e-09 38.8 0.6 2.7 3 0 0 3 3 3 2 SRS domain SAG PF04092.13 PFH33004.1 - 2.5e-13 51.0 13.3 4.9e-11 43.5 2.2 3.4 2 1 0 2 2 2 2 SRS domain SAG PF04092.13 PFH33005.1 - 8e-11 42.8 5.0 0.00044 21.0 0.0 2.7 2 1 0 2 2 2 2 SRS domain Sushi PF00084.20 PFH33005.1 - 0.0023 18.5 1.6 0.97 10.1 0.0 2.9 3 1 0 3 3 3 2 Sushi repeat (SCR repeat) SAG PF04092.13 PFH33006.1 - 1.4e-13 51.8 11.6 8.7e-09 36.3 1.4 2.9 2 1 0 2 2 2 2 SRS domain Ribosomal_S7e PF01251.18 PFH33007.1 - 4.6e-69 231.9 9.8 5.2e-69 231.7 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e FtsQ PF03799.15 PFH33007.1 - 0.052 14.4 0.4 0.11 13.3 0.4 1.7 1 1 0 1 1 1 0 Cell division protein FtsQ LRR_4 PF12799.7 PFH33008.1 - 7.5e-12 45.3 8.7 1.2e-06 28.7 1.7 3.4 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PFH33008.1 - 3.5e-11 42.9 3.3 6.2e-11 42.1 3.3 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PFH33008.1 - 4.1e-06 26.5 6.2 4.1e-06 26.5 6.2 3.4 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.6 PFH33008.1 - 0.051 13.7 6.7 3 8.1 0.1 3.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 PFH33008.1 - 4 8.4 6.8 27 5.8 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat PIH1_CS PF18201.1 PFH33009.1 - 0.02 15.3 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 PIH1 CS-like domain DUF4908 PF16252.5 PFH33009.1 - 0.068 12.7 0.6 0.66 9.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4908) DUF1936 PF09151.10 PFH33009.1 - 0.91 9.5 2.6 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Pkinase_Tyr PF07714.17 PFH33010.1 - 2.2e-49 168.1 0.0 7.7e-30 104.0 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 PFH33010.1 - 4.1e-46 157.5 0.0 4.4e-29 101.6 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain SAM_2 PF07647.17 PFH33010.1 - 1.1e-07 31.8 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MORN PF02493.20 PFH33010.1 - 0.0016 18.2 25.5 0.0021 17.8 0.2 4.9 5 0 0 5 5 5 2 MORN repeat Pkinase_fungal PF17667.1 PFH33010.1 - 0.002 17.0 0.1 0.0051 15.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase SAM_1 PF00536.30 PFH33010.1 - 0.0037 17.7 0.0 0.0076 16.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 PFH33010.1 - 0.067 12.5 0.0 1.1 8.5 0.0 2.5 3 0 0 3 3 3 0 Kinase-like DAGK_acc PF00609.19 PFH33011.1 - 4.9e-40 137.5 0.0 1.8e-22 80.4 0.0 2.3 2 0 0 2 2 2 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 PFH33011.1 - 1.7e-20 72.9 0.0 4.9e-13 48.8 0.0 2.9 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 PFH33011.1 - 8.9e-13 47.9 28.3 8e-08 32.0 3.0 3.2 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) CENP-T_C PF15511.6 PFH33012.1 - 6.1e-09 36.0 0.1 7.3e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 PFH33012.1 - 0.00023 21.3 0.0 0.0003 20.9 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 PFH33012.1 - 0.00051 20.4 0.1 0.00073 19.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 PFH33012.1 - 0.00055 20.2 0.0 0.00079 19.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PFH33012.1 - 0.0013 19.1 0.1 0.0015 18.9 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 PFH33012.1 - 0.023 14.8 0.0 0.026 14.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 PFH33012.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 PFH33012.1 - 0.066 13.0 0.2 0.081 12.7 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TAFII28 PF04719.14 PFH33012.1 - 0.069 13.2 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DUF4231 PF14015.6 PFH33014.1 - 0.028 14.9 0.4 0.058 13.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) stn_TNFRSF12A PF12191.8 PFH33014.1 - 0.33 11.2 1.4 0.4 10.9 0.0 1.9 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain APG6_N PF17675.1 PFH33015.1 - 0.007 16.9 26.8 0.007 16.9 26.8 12.1 1 1 10 12 12 12 4 Apg6 coiled-coil region LPP PF04728.13 PFH33015.1 - 0.032 14.6 1.0 0.032 14.6 1.0 14.6 10 4 6 16 16 16 0 Lipoprotein leucine-zipper Rib_5-P_isom_A PF06026.14 PFH33016.1 - 3.5e-58 196.0 0.0 4.2e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 PFH33016.1 - 0.0048 16.8 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 1 DeoR C terminal sensor domain Malectin PF11721.8 PFH33016.1 - 0.12 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Malectin domain BolA PF01722.18 PFH33017.1 - 3.3e-25 88.1 0.1 4.4e-25 87.8 0.1 1.2 1 0 0 1 1 1 1 BolA-like protein Ribosomal_L37e PF01907.19 PFH33018.1 - 1.3e-25 89.3 13.5 2.6e-25 88.3 13.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.18 PFH33018.1 - 0.00064 19.8 1.5 0.001 19.1 1.3 1.4 1 1 0 1 1 1 1 SelR domain DZR PF12773.7 PFH33018.1 - 0.028 14.4 1.7 0.038 14.0 1.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-Mss51 PF13824.6 PFH33018.1 - 0.78 9.9 3.5 14 5.8 0.1 2.2 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 GTP1_OBG PF01018.22 PFH33019.1 - 1.6e-31 109.0 6.9 8.7e-13 48.1 0.4 3.7 3 0 0 3 3 3 3 GTP1/OBG DUF1967 PF09269.11 PFH33019.1 - 2.1e-07 30.8 0.0 4.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) cobW PF02492.19 PFH33019.1 - 0.0079 15.8 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 PFH33019.1 - 0.015 15.7 0.4 0.14 12.5 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.12 PFH33019.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RAP PF08373.10 PFH33020.1 - 3.7e-10 39.8 0.0 5.7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 RAP domain MAJIN PF15077.6 PFH33022.1 - 7.8 6.2 9.2 7.5 6.3 8.3 1.5 1 1 0 1 1 1 0 Membrane-anchored junction protein Pkinase PF00069.25 PFH33023.1 - 4.6e-15 55.7 0.0 0.00048 19.6 0.0 4.0 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33023.1 - 3e-05 23.4 0.0 0.0011 18.3 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 PFH33023.1 - 0.1 12.0 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_4 PF14570.6 PFH33025.1 - 4.5e-20 71.2 11.3 7.6e-20 70.5 11.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 PFH33025.1 - 7.8e-07 28.9 7.6 1.3e-06 28.2 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 PFH33025.1 - 0.00046 19.9 0.0 0.00092 19.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 PFH33025.1 - 0.00092 19.5 10.4 0.0015 18.8 10.4 1.4 1 0 0 1 1 1 1 Ring finger domain Torus PF16131.5 PFH33025.1 - 0.018 15.7 0.1 0.018 15.7 0.1 2.6 2 0 0 2 2 2 0 Torus domain zf-C3HC4 PF00097.25 PFH33025.1 - 0.031 14.1 8.9 0.053 13.4 8.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PFH33025.1 - 0.47 10.3 7.0 6 6.8 7.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 PFH33025.1 - 1.2 9.1 4.8 4.4 7.2 0.8 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif Peptidase_S8 PF00082.22 PFH33026.1 - 6.4e-39 134.0 0.9 6.4e-39 134.0 0.9 3.0 3 1 0 3 3 3 1 Subtilase family Pkinase PF00069.25 PFH33028.1 - 1.4e-40 139.3 0.0 1.3e-19 70.7 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33028.1 - 6.2e-16 58.5 0.0 2.2e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 PFH33028.1 - 0.0001 21.2 0.0 0.0002 20.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PFH33028.1 - 0.017 14.5 0.2 0.06 12.7 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PFH33028.1 - 0.018 14.4 0.1 0.19 11.0 0.1 2.0 2 0 0 2 2 2 0 Kinase-like EF-hand_7 PF13499.6 PFH33029.1 - 3.3e-09 37.1 0.0 0.00052 20.4 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PFH33029.1 - 1.3e-08 33.8 0.1 0.00016 21.0 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 PFH33029.1 - 1.2e-07 30.9 0.3 3.3e-07 29.5 0.2 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 PFH33029.1 - 1.1e-06 28.1 1.6 2.2e-05 24.0 0.2 2.9 3 0 0 3 3 3 1 EF-hand domain Mlo PF03094.15 PFH33029.1 - 1.5e-05 23.6 8.4 0.0033 15.8 2.9 3.3 2 1 1 3 3 3 3 Mlo family EF-hand_8 PF13833.6 PFH33029.1 - 0.0014 18.4 0.1 0.03 14.2 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair TMEM132D_C PF15706.5 PFH33029.1 - 0.094 12.5 0.0 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4605 PF15378.6 PFH33029.1 - 0.99 9.3 5.8 0.49 10.3 1.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) Pkinase PF00069.25 PFH33030.1 - 1.5e-49 168.7 0.0 2.5e-31 109.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33030.1 - 1.2e-31 110.0 0.0 9.1e-25 87.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PFH33030.1 - 0.0012 18.3 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PFH33030.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CH_2 PF06294.11 PFH33031.1 - 1.6e-18 66.6 0.0 3.3e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein ADK PF00406.22 PFH33031.1 - 0.00036 20.7 0.0 3.4 7.8 0.0 3.6 3 0 0 3 3 3 2 Adenylate kinase Hydin_ADK PF17213.3 PFH33031.1 - 0.11 12.8 0.0 0.11 12.8 0.0 4.2 5 0 0 5 5 5 0 Hydin Adenylate kinase-like domain AAA_17 PF13207.6 PFH33031.1 - 0.14 12.6 2.3 1.8 9.0 0.0 3.6 3 1 0 3 3 3 0 AAA domain RNB PF00773.19 PFH33032.1 - 3.7e-84 282.9 0.0 2.5e-83 280.1 0.0 2.1 1 1 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 PFH33032.1 - 5.4e-08 32.7 0.0 1.4e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 PFH33032.1 - 0.047 13.4 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Rrp44-like cold shock domain E1_dh PF00676.20 PFH33033.1 - 2.6e-79 266.3 0.0 3.3e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 PFH33033.1 - 0.00031 20.1 0.0 0.0006 19.1 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Proteasome PF00227.26 PFH33034.1 - 3e-58 196.5 0.0 3.8e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PFH33034.1 - 1.9e-13 49.8 0.2 3.4e-13 49.0 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Herpes_UL82_83 PF05784.11 PFH33034.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Betaherpesvirus UL82/83 protein N terminus tRNA_NucTransf2 PF09249.11 PFH33034.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain START PF01852.19 PFH33035.1 - 0.00039 19.9 0.0 0.00084 18.8 0.0 1.5 1 1 0 1 1 1 1 START domain Aminotran_5 PF00266.19 PFH33037.1 - 5.8e-45 153.8 0.0 7e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 PFH33037.1 - 1.1e-05 24.9 0.0 0.00035 19.8 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 PFH33037.1 - 0.0057 16.0 0.1 0.38 10.0 0.0 2.3 2 1 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Transketolase_C PF02780.20 PFH33037.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain CDC50 PF03381.15 PFH33038.1 - 7.3e-71 238.9 0.0 9e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Robl_LC7 PF03259.17 PFH33039.1 - 1.2e-12 47.4 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain HetR_C PF18460.1 PFH33039.1 - 0.1 12.6 0.0 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Myosin_head PF00063.21 PFH33040.1 - 5.7e-183 609.8 0.0 6.9e-183 609.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 PFH33040.1 - 0.011 16.1 0.0 0.039 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 PFH33040.1 - 0.019 14.8 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Ran_BP1 PF00638.18 PFH33040.1 - 0.026 14.8 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 RanBP1 domain TsaE PF02367.17 PFH33040.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3402 PF11882.8 PFH33041.1 - 0.027 13.6 0.2 0.091 11.8 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3402) UTP15_C PF09384.10 PFH33043.1 - 1e-26 93.4 1.8 2e-26 92.5 1.8 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 PFH33043.1 - 3.3e-15 56.2 13.5 8.4e-08 32.8 0.3 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH33043.1 - 0.00017 21.9 0.0 1.1 9.6 0.0 4.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_phi PF04931.13 PFH33043.1 - 0.0048 15.1 5.6 0.0084 14.3 5.6 1.3 1 0 0 1 1 1 1 DNA polymerase phi FYDLN_acid PF09538.10 PFH33043.1 - 0.018 15.7 3.2 0.24 12.1 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) AOC_like PF18678.1 PFH33043.1 - 0.08 12.5 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain Cytochrom_D1 PF02239.16 PFH33043.1 - 0.1 11.1 0.1 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain RPN2_C PF18004.1 PFH33043.1 - 2.8 7.8 7.3 5.4 6.9 7.3 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Kinase-like PF14531.6 PFH33044.1 - 8.3e-27 94.2 0.0 1.2e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH33044.1 - 3.5e-09 36.4 0.0 6.8e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33044.1 - 0.0085 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase 5_nucleotid_C PF02872.18 PFH33046.1 - 4.2e-33 114.8 0.0 9.3e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PFH33046.1 - 1.3e-06 29.0 1.2 8.8e-06 26.4 1.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase dCMP_cyt_deam_2 PF08211.12 PFH33047.1 - 1.5e-18 67.3 2.6 2.2e-12 47.3 0.8 2.5 3 0 0 3 3 3 2 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.23 PFH33047.1 - 2.3e-14 53.1 4.5 2.7e-09 36.8 0.1 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 PFH33047.1 - 0.33 10.5 10.5 2 8.0 4.0 3.0 3 1 0 3 3 3 0 A distinct subfamily of CDD/CDA-like deaminases PRiA4_ORF3 PF07929.11 PFH33048.1 - 0.22 11.2 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein Rab5ip PF07019.12 PFH33050.1 - 3.3e-16 59.6 6.2 4.3e-16 59.3 6.2 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) RCC1 PF00415.18 PFH33051.1 - 3.9e-33 113.8 19.6 8e-05 23.2 0.0 11.5 11 0 0 11 11 11 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH33051.1 - 6.9e-27 92.6 38.8 3.4e-09 36.3 0.2 8.6 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat PMM PF03332.13 PFH33052.1 - 3.9e-90 301.5 0.0 4.5e-90 301.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 PFH33052.1 - 1.1e-09 38.5 0.0 6.1e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PFH33052.1 - 7.3e-09 35.5 0.0 0.00056 19.5 0.0 2.0 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 PFH33052.1 - 0.021 14.9 0.1 2.1 8.4 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PFH33052.1 - 0.068 13.5 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 PFH33052.1 - 0.28 11.6 0.7 3.1 8.1 0.3 2.4 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase ribosomal_L24 PF17136.4 PFH33054.1 - 7.4e-14 51.9 0.0 1.5e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 PFH33054.1 - 3.3e-06 26.8 1.0 5.7e-06 26.1 1.0 1.4 1 0 0 1 1 1 1 KOW motif PIG-H PF10181.9 PFH33057.1 - 2.6e-15 56.0 0.3 4e-15 55.4 0.3 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Fringe PF02434.16 PFH33058.1 - 3.3e-23 82.4 0.0 2e-11 43.8 0.0 3.2 3 0 0 3 3 3 3 Fringe-like Galactosyl_T PF01762.21 PFH33058.1 - 0.0013 18.6 0.0 0.55 10.0 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Ribosomal_L22e PF01776.17 PFH33059.1 - 8.9e-44 148.3 1.5 1.1e-43 148.1 1.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family FERM_M PF00373.18 PFH33059.1 - 0.04 14.3 0.0 0.046 14.1 0.0 1.2 1 0 0 1 1 1 0 FERM central domain IMCp PF12314.8 PFH33060.1 - 2.1e-19 69.6 35.1 3.7e-18 65.6 25.7 2.3 1 1 1 2 2 2 2 Inner membrane complex protein Pescadillo_N PF06732.11 PFH33062.1 - 7.6e-88 294.6 0.5 1.2e-87 293.9 0.5 1.2 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 PFH33062.1 - 1.2e-05 25.6 0.0 5.6e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 PFH33062.1 - 0.014 15.7 0.0 0.16 12.3 0.0 2.4 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain CDC45 PF02724.14 PFH33062.1 - 2.2 6.5 22.7 0.023 13.0 5.6 2.2 2 0 0 2 2 2 0 CDC45-like protein Chorein_N PF12624.7 PFH33063.1 - 5.3e-07 29.8 0.0 7.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 2-Hacid_dh_C PF02826.19 PFH33065.1 - 1.5e-42 145.0 0.5 3.7e-42 143.7 0.2 1.8 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PFH33065.1 - 1.4e-32 112.2 0.5 2.8e-32 111.2 0.5 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 PFH33065.1 - 0.002 17.9 0.1 0.0087 15.8 0.1 2.1 1 1 0 1 1 1 1 ACT domain ACT_4 PF13291.6 PFH33065.1 - 0.036 14.6 0.3 0.28 11.8 0.0 2.6 2 0 0 2 2 2 0 ACT domain RabGAP-TBC PF00566.18 PFH33066.1 - 0.00014 21.6 0.1 0.00024 20.8 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cementoin PF10511.9 PFH33066.1 - 0.23 11.8 1.2 0.7 10.3 1.2 1.9 1 0 0 1 1 1 0 Trappin protein transglutaminase binding domain HAD PF12710.7 PFH33067.1 - 0.0051 17.2 0.0 0.012 16.1 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PFH33067.1 - 0.054 13.6 2.5 4 7.5 0.0 2.6 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PFH33067.1 - 0.083 13.2 0.7 12 6.1 0.5 2.8 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-RanBP PF00641.18 PFH33069.1 - 4.7e-06 25.8 23.0 0.0013 18.0 8.5 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Ipi1_N PF12333.8 PFH33069.1 - 0.066 13.8 0.3 16 6.2 0.2 2.6 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation DUF35_N PF12172.8 PFH33069.1 - 0.086 12.7 15.8 0.88 9.5 1.6 2.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PHD PF00628.29 PFH33069.1 - 0.1 12.5 2.5 9.6 6.2 0.1 3.3 3 0 0 3 3 3 0 PHD-finger DZR PF12773.7 PFH33069.1 - 0.2 11.7 11.4 0.88 9.7 2.2 2.6 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 PFH33069.1 - 0.36 10.9 6.0 2.4 8.2 0.2 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrom_c3_2 PF14537.6 PFH33069.1 - 0.51 10.8 6.3 8.1 7.0 1.9 2.6 2 0 0 2 2 2 0 Cytochrome c3 WD40 PF00400.32 PFH33070.1 - 0.0049 17.7 0.0 0.17 12.8 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Profilin PF00235.19 PFH33071.1 - 4.5e-24 85.1 0.1 5.4e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 Profilin DUF2076 PF09849.9 PFH33072.1 - 0.021 14.9 1.1 0.037 14.1 1.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TEX33 PF15400.6 PFH33072.1 - 0.076 13.5 0.6 0.38 11.2 0.1 2.1 1 1 1 2 2 2 0 Testis-expressed sequence 33 protein family TFIIS_M PF07500.14 PFH33073.1 - 4.3e-24 85.2 0.8 9.6e-24 84.0 0.8 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 PFH33073.1 - 1.9e-18 66.0 5.7 5.4e-18 64.6 5.7 1.8 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 PFH33073.1 - 2.1e-12 46.8 0.1 4.7e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TetR_C_15 PF17918.1 PFH33074.1 - 0.014 16.1 1.9 12 6.7 0.2 3.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3546 PF12066.8 PFH33075.1 - 3.6e-14 52.9 2.5 6.8e-14 52.0 2.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 PFH33075.1 - 2e-08 34.9 1.0 7.8e-08 32.9 1.0 2.1 1 1 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 PFH33075.1 - 0.0015 18.3 0.2 0.0054 16.5 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) PocR PF10114.9 PFH33075.1 - 0.031 14.1 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 Sensory domain found in PocR zf-C2H2 PF00096.26 PFH33075.1 - 0.054 14.0 3.5 0.13 12.7 3.5 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Rep_fac-A_C PF08646.10 PFH33075.1 - 0.075 12.8 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-C2H2_4 PF13894.6 PFH33075.1 - 0.64 11.0 3.5 2.5 9.2 3.5 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger VWC PF00093.18 PFH33076.1 - 0.057 13.7 15.0 0.82 10.0 6.8 2.4 2 0 0 2 2 2 0 von Willebrand factor type C domain HutP PF09021.11 PFH33076.1 - 0.38 11.1 2.9 0.34 11.2 0.9 2.0 2 0 0 2 2 2 0 HutP Amidohydro_2 PF04909.14 PFH33077.1 - 6.5e-10 39.3 0.0 1.5e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 PFH33077.1 - 0.00019 20.9 0.1 0.00039 19.9 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase family Ribosomal_L27 PF01016.19 PFH33078.1 - 2.9e-27 94.5 0.6 4.6e-27 93.8 0.6 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein ketoacyl-synt PF00109.26 PFH33079.1 - 3e-54 184.3 1.2 5.9e-54 183.3 0.8 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PFH33079.1 - 1.4e-38 131.5 0.3 3.3e-38 130.3 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Prefoldin_2 PF01920.20 PFH33080.1 - 1.7e-18 66.5 1.6 2.2e-18 66.2 1.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit BicD PF09730.9 PFH33080.1 - 0.0048 15.4 0.0 0.0061 15.0 0.0 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D APG6_N PF17675.1 PFH33080.1 - 0.024 15.2 2.4 2 8.9 0.3 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 PFH33080.1 - 0.059 13.6 3.1 0.27 11.5 3.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4600 PF15372.6 PFH33080.1 - 0.088 13.2 1.0 0.18 12.3 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Syntaxin-6_N PF09177.11 PFH33080.1 - 0.11 13.0 0.9 1.9 9.1 0.2 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal KAP PF05804.12 PFH33081.1 - 2.7e-17 62.2 0.0 3e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) DUF5396 PF17374.2 PFH33081.1 - 0.056 11.3 0.0 0.072 11.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5396) Arm PF00514.23 PFH33081.1 - 0.083 13.0 0.1 11 6.2 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat U79_P34 PF03064.16 PFH33084.1 - 5.9 6.2 10.8 13 5.1 10.8 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 EMC3_TMCO1 PF01956.16 PFH33085.1 - 2.9e-33 115.0 0.2 2.9e-33 115.0 0.2 2.1 1 1 1 2 2 2 1 Integral membrane protein EMC3/TMCO1-like DEAD PF00270.29 PFH33086.1 - 2.9e-11 43.5 0.0 5.8e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH33086.1 - 0.00024 21.4 0.0 0.00079 19.8 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain BolA PF01722.18 PFH33087.1 - 5.3e-19 68.3 0.0 1.8e-18 66.5 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein Acetyltransf_1 PF00583.25 PFH33088.1 - 1.3e-10 41.5 0.2 4e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PFH33088.1 - 0.00067 20.0 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PFH33088.1 - 0.013 15.5 0.5 0.057 13.4 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF4541 PF15074.6 PFH33088.1 - 0.059 14.0 0.0 0.23 12.1 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) Acetyltransf_CG PF14542.6 PFH33088.1 - 0.083 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ribosomal_L3 PF00297.22 PFH33089.1 - 1.1e-11 44.3 3.3 1.4e-08 34.1 2.2 2.9 2 1 1 3 3 3 2 Ribosomal protein L3 WD40 PF00400.32 PFH33090.1 - 4.2e-08 33.7 8.5 0.0015 19.3 0.1 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat PhrC_PhrF PF11131.8 PFH33090.1 - 0.13 11.9 1.6 0.57 9.8 1.6 2.1 1 0 0 1 1 1 0 Rap-phr extracellular signalling Kinesin PF00225.23 PFH33091.1 - 2.5e-94 315.9 0.0 4.5e-94 315.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PFH33091.1 - 1.6e-21 76.8 0.0 5.6e-21 75.0 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 PFH33091.1 - 0.074 13.3 0.2 0.91 9.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 PFH33091.1 - 0.078 12.5 0.0 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DALR_1 PF05746.15 PFH33091.1 - 0.12 12.5 0.9 0.25 11.5 0.1 2.0 2 0 0 2 2 2 0 DALR anticodon binding domain BBP1_C PF15272.6 PFH33091.1 - 0.27 11.0 5.7 1.1 9.1 0.1 2.7 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal TEX13 PF15186.6 PFH33091.1 - 0.94 9.1 6.7 2.8 7.6 0.1 3.3 1 1 2 3 3 3 0 Testis-expressed sequence 13 protein family AAA_23 PF13476.6 PFH33091.1 - 2.3 8.7 12.5 19 5.6 3.1 3.3 3 0 0 3 3 3 0 AAA domain DUF2203 PF09969.9 PFH33091.1 - 4.4 8.0 9.8 2.2 9.0 0.3 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Suf PF05843.14 PFH33092.1 - 5.9e-25 88.9 0.0 2.7e-19 70.3 0.1 4.0 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_9 PF13371.6 PFH33092.1 - 0.00042 20.4 0.4 0.013 15.6 0.1 3.7 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH33092.1 - 0.002 18.3 0.9 0.0047 17.1 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PFH33092.1 - 0.0065 16.8 0.4 0.15 12.5 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 PFH33092.1 - 0.019 15.5 4.3 0.88 10.1 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH33092.1 - 0.072 13.8 1.8 25 5.8 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 PFH33092.1 - 0.24 12.3 0.0 0.24 12.3 0.0 9.4 6 4 7 13 13 13 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PFH33092.1 - 0.41 10.6 2.3 8.7 6.4 0.2 3.7 5 0 0 5 5 5 0 Mad3/BUB1 homology region 1 Rav1p_C PF12234.8 PFH33093.1 - 4.7e-27 94.7 0.6 1.2e-21 76.8 0.4 3.8 4 0 0 4 4 4 3 RAVE protein 1 C terminal Cpn60_TCP1 PF00118.24 PFH33094.1 - 2.4e-153 511.3 11.6 2.8e-153 511.1 11.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 PFH33094.1 - 0.04 13.4 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Telomere recombination AAA PF00004.29 PFH33095.1 - 1.2e-44 151.9 0.3 1.2e-43 148.7 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PFH33095.1 - 9.4e-09 34.9 0.0 2.5e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 PFH33095.1 - 4.3e-08 33.5 0.0 9.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PFH33095.1 - 4.5e-08 33.2 0.2 1.5e-07 31.5 0.2 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 PFH33095.1 - 1.5e-07 31.2 0.1 1.1e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 PFH33095.1 - 5.9e-06 26.8 1.8 0.00083 19.8 0.0 3.1 3 1 1 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 PFH33095.1 - 3.4e-05 24.1 0.6 0.0058 16.9 0.1 2.8 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 PFH33095.1 - 3.5e-05 23.6 0.0 0.00018 21.3 0.0 2.2 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 PFH33095.1 - 4e-05 22.9 0.0 0.00011 21.4 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF815) NTPase_1 PF03266.15 PFH33095.1 - 0.00014 21.8 0.1 0.018 14.9 0.0 2.7 3 0 0 3 3 3 1 NTPase AAA_18 PF13238.6 PFH33095.1 - 0.00014 22.4 0.0 0.001 19.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PFH33095.1 - 0.00041 20.6 0.5 0.0012 19.1 0.0 2.1 3 0 0 3 3 1 1 AAA domain AAA_25 PF13481.6 PFH33095.1 - 0.00073 19.2 2.6 0.17 11.5 0.1 3.0 2 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 PFH33095.1 - 0.0012 19.2 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 PFH33095.1 - 0.0016 18.2 0.0 0.0037 17.0 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 PFH33095.1 - 0.0018 18.5 0.0 0.0049 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 PFH33095.1 - 0.0018 17.7 0.1 0.0041 16.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 PFH33095.1 - 0.0024 17.1 0.0 0.0088 15.3 0.0 1.9 2 1 0 2 2 2 1 TIP49 P-loop domain AAA_3 PF07726.11 PFH33095.1 - 0.0028 17.5 0.1 0.059 13.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PFH33095.1 - 0.0042 16.6 0.2 0.028 13.9 0.2 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 PFH33095.1 - 0.005 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 PFH33095.1 - 0.0054 16.7 0.3 0.21 11.5 0.0 2.9 2 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 PFH33095.1 - 0.0062 16.3 0.2 0.015 15.0 0.2 1.7 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 PFH33095.1 - 0.017 14.2 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 PFH33095.1 - 0.018 14.8 0.2 0.12 12.1 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 PFH33095.1 - 0.02 15.0 0.1 0.051 13.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 PFH33095.1 - 0.028 14.3 0.2 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 NACHT domain TniB PF05621.11 PFH33095.1 - 0.028 13.8 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_11 PF13086.6 PFH33095.1 - 0.029 14.2 0.1 0.51 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF1151 PF06625.11 PFH33095.1 - 0.033 14.1 1.2 0.069 13.1 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) AAA_30 PF13604.6 PFH33095.1 - 0.037 13.7 0.3 0.11 12.2 0.3 1.8 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 PFH33095.1 - 0.045 13.1 1.0 0.72 9.2 0.0 2.5 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.6 PFH33095.1 - 0.068 13.3 0.0 0.52 10.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain DnaB_C PF03796.15 PFH33095.1 - 0.072 12.4 1.2 7.8 5.7 0.1 2.6 2 1 1 3 3 3 0 DnaB-like helicase C terminal domain Corona_S2 PF01601.16 PFH33095.1 - 0.08 11.4 0.1 2.5 6.5 0.0 2.1 1 1 1 2 2 2 0 Coronavirus S2 glycoprotein NB-ARC PF00931.22 PFH33095.1 - 0.095 11.9 0.1 0.47 9.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 PFH33095.1 - 0.12 12.8 0.5 0.48 10.9 0.1 2.4 2 2 0 2 2 2 0 ABC transporter Torsin PF06309.11 PFH33095.1 - 0.15 12.1 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Torsin Pro_isomerase PF00160.21 PFH33096.1 - 8.2e-38 130.2 0.2 2.2e-37 128.8 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SYF2 PF08231.12 PFH33096.1 - 3.6e-33 115.2 11.4 3.6e-33 115.2 11.4 3.2 1 1 1 2 2 2 1 SYF2 splicing factor SR-25 PF10500.9 PFH33096.1 - 0.0042 16.7 15.0 0.0042 16.7 15.0 3.5 2 1 2 4 4 4 1 Nuclear RNA-splicing-associated protein Transposase_20 PF02371.16 PFH33096.1 - 0.11 12.8 0.7 0.43 10.9 0.7 2.0 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family p25-alpha PF05517.12 PFH33097.1 - 4.5e-33 114.6 4.0 5.9e-33 114.2 4.0 1.3 1 1 0 1 1 1 1 p25-alpha HAUS2 PF15003.6 PFH33099.1 - 0.022 14.5 1.6 0.022 14.5 1.6 4.0 1 1 2 4 4 4 0 HAUS augmin-like complex subunit 2 GD_AH_C PF04295.13 PFH33099.1 - 1 8.1 9.1 1.4 7.7 2.2 2.6 2 1 0 2 2 2 0 D-galactarate dehydratase / Altronate hydrolase, C terminus DUF3887 PF13026.6 PFH33099.1 - 1.3 9.9 8.2 0.23 12.3 1.2 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF3887) EF-hand_1 PF00036.32 PFH33100.1 - 1.2e-16 58.9 2.7 9.1e-05 21.7 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PFH33100.1 - 8e-13 48.6 1.2 1.9e-06 28.2 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH33100.1 - 1.4e-12 46.4 4.6 0.011 15.6 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PFH33100.1 - 1.6e-10 40.7 1.9 6.7e-06 25.9 0.1 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 PFH33100.1 - 3.3e-08 33.7 0.2 0.0011 19.2 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PFH33100.1 - 0.002 17.5 3.1 0.0072 15.8 0.3 3.0 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 PFH33100.1 - 0.0084 16.4 0.0 0.35 11.2 0.0 2.3 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region GPHH PF16905.5 PFH33100.1 - 0.083 12.7 0.0 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated Macro PF01661.21 PFH33101.1 - 2.5e-05 24.3 0.0 6.2e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Macro domain GLTSCR1 PF15249.6 PFH33102.1 - 0.0034 17.8 0.1 0.0088 16.5 0.1 1.6 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein GHMP_kinases_N PF00288.26 PFH33103.1 - 3.5e-13 49.6 2.8 3.5e-13 49.6 2.8 3.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 PFH33103.1 - 2.8e-12 46.8 0.3 1.5e-11 44.5 0.1 2.4 2 0 0 2 2 2 1 GHMP kinases C terminal TFIID_30kDa PF03540.13 PFH33104.1 - 0.062 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit FmiP_Thoc5 PF09766.9 PFH33105.1 - 7.4e-12 45.2 13.7 7.4e-12 45.2 13.7 2.5 3 1 0 3 3 3 1 Fms-interacting protein/Thoc5 Cytochrom_B_C PF00032.17 PFH33106.1 - 1.9e-09 37.7 6.6 2.2e-09 37.5 6.6 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD ThiF PF00899.21 PFH33109.1 - 1.2e-30 106.7 0.0 2.2e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 PFH33109.1 - 1e-23 84.5 0.0 7.2e-11 42.3 0.0 3.8 3 1 0 3 3 3 3 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus OTU PF02338.19 PFH33109.1 - 3.3e-14 53.5 0.0 6.6e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PFH33109.1 - 0.0048 16.4 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain Ribosom_S12_S23 PF00164.25 PFH33111.1 - 4.5e-50 168.0 0.3 5.8e-50 167.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_15 PF09445.10 PFH33111.1 - 0.11 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Peptidase_M6 PF05547.11 PFH33111.1 - 0.21 9.8 0.0 0.26 9.6 0.0 1.0 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Josephin PF02099.17 PFH33112.1 - 2.8e-41 141.3 0.0 8.4e-41 139.8 0.0 1.7 2 0 0 2 2 2 1 Josephin UBX PF00789.20 PFH33112.1 - 7.5e-10 38.9 0.0 1.4e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 UBX domain G10 PF01125.17 PFH33112.1 - 0.1 12.4 0.1 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 G10 protein DUF4795 PF16043.5 PFH33113.1 - 1.3 8.6 6.8 0.38 10.3 3.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Pkinase PF00069.25 PFH33114.1 - 2e-28 99.5 0.0 6.7e-17 61.7 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33114.1 - 9.9e-13 48.0 0.0 4.6e-09 36.0 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 PFH33114.1 - 0.00048 20.1 0.0 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PFH33114.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family REV PF00424.18 PFH33114.1 - 0.029 14.4 3.0 0.2 11.7 3.0 2.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) FTA2 PF13095.6 PFH33114.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 TPR_1 PF00515.28 PFH33117.1 - 8e-12 44.5 6.5 1.4e-05 24.7 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PFH33117.1 - 2e-10 39.9 6.7 2.2e-05 24.2 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 PFH33117.1 - 4e-06 26.9 2.3 1.7e-05 24.9 2.3 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 PFH33117.1 - 1.6e-05 24.5 0.5 0.00097 18.8 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 PFH33117.1 - 0.00073 19.7 0.0 0.003 17.8 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 PFH33117.1 - 0.00095 19.2 1.5 0.37 11.1 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 PFH33117.1 - 0.015 15.8 0.5 0.015 15.8 0.5 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat G6PD_N PF00479.22 PFH33117.1 - 0.091 13.4 3.6 0.25 12.0 3.6 1.7 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Phage_holin_3_6 PF07332.11 PFH33117.1 - 0.26 11.3 1.9 3.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III TPR_6 PF13174.6 PFH33117.1 - 7.9 7.4 6.6 2.3 9.0 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat EF-hand_7 PF13499.6 PFH33119.1 - 5e-22 78.1 13.7 4.2e-09 36.7 1.2 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PFH33119.1 - 1.3e-21 74.6 13.2 0.00033 20.3 0.2 6.1 5 1 1 6 6 6 5 EF-hand domain EF-hand_1 PF00036.32 PFH33119.1 - 9.2e-21 71.8 21.4 0.00057 19.2 1.1 6.1 6 0 0 6 6 6 5 EF hand EF-hand_5 PF13202.6 PFH33119.1 - 8.4e-20 69.3 20.2 2.6e-05 23.5 0.0 6.0 6 0 0 6 6 6 4 EF hand SPARC_Ca_bdg PF10591.9 PFH33119.1 - 4.6e-12 46.2 9.8 0.00038 20.8 0.3 3.7 2 1 2 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 PFH33119.1 - 1.6e-10 40.7 11.1 0.0033 17.2 0.1 5.2 4 1 1 5 5 5 4 EF-hand domain pair TRCF PF03461.15 PFH33119.1 - 0.0047 17.3 2.8 2.3 8.7 0.0 2.8 3 0 0 3 3 3 2 TRCF domain Dockerin_1 PF00404.18 PFH33119.1 - 0.025 14.8 7.6 2.5 8.4 0.0 4.2 4 1 1 5 5 5 0 Dockerin type I domain CRISPR_Cse2 PF09485.10 PFH33119.1 - 0.061 13.9 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Latarcin PF10279.9 PFH33119.1 - 0.52 10.8 4.2 0.34 11.3 1.2 2.2 2 1 0 2 2 2 0 Latarcin precursor IF2_N PF04760.15 PFH33119.1 - 1 9.3 5.5 5.1 7.0 1.4 2.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Btz PF09405.10 PFH33120.1 - 1.5e-10 41.4 0.9 6.9e-10 39.3 0.9 2.2 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding SNF2_N PF00176.23 PFH33121.1 - 8.1e-44 149.8 0.1 8.6e-36 123.4 0.0 2.7 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 PFH33121.1 - 7.8e-20 71.3 0.1 1.7e-18 66.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH33121.1 - 6e-08 32.9 0.0 1.6e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PFH33121.1 - 0.00012 21.9 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 PFH33121.1 - 0.00064 19.0 0.0 0.0016 17.7 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF1397 PF07165.11 PFH33121.1 - 0.091 12.2 1.0 0.43 10.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1397) RBM39linker PF15519.6 PFH33124.1 - 0.0027 18.8 0.2 0.0051 17.9 0.2 1.5 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein HOIP-UBA PF16678.5 PFH33124.1 - 0.086 12.8 0.2 0.44 10.6 0.0 1.9 1 1 1 2 2 2 0 HOIP UBA domain pair NTR2 PF15458.6 PFH33124.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Nineteen complex-related protein 2 zf-RING_2 PF13639.6 PFH33125.1 - 1.4e-10 41.4 6.3 2.5e-10 40.5 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PFH33125.1 - 1.8e-06 28.1 4.5 4.4e-06 26.9 4.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PFH33125.1 - 2e-06 27.4 1.8 4.3e-06 26.4 1.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PFH33125.1 - 5.2e-06 26.2 4.3 1e-05 25.3 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PFH33125.1 - 6.6e-06 25.9 3.9 1.1e-05 25.2 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH33125.1 - 1.2e-05 25.1 4.4 1.9e-05 24.5 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PFH33125.1 - 0.0003 20.8 1.3 0.00069 19.6 1.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 PFH33125.1 - 0.0008 19.2 2.4 0.0014 18.4 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH33125.1 - 0.0015 18.5 1.1 0.0015 18.5 1.1 1.7 1 1 0 1 1 1 1 RING-type zinc-finger RINGv PF12906.7 PFH33125.1 - 0.0099 16.0 5.0 0.018 15.2 5.0 1.5 1 0 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 PFH33125.1 - 0.014 15.0 3.2 0.026 14.1 3.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 PFH33125.1 - 0.13 12.2 4.6 0.25 11.2 4.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 PFH33125.1 - 0.39 10.6 1.8 0.77 9.7 1.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 PFH33125.1 - 0.58 10.5 4.0 0.97 9.8 4.0 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 PFH33125.1 - 1 9.2 2.9 1.8 8.4 2.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 PFH33125.1 - 1.3 9.2 4.2 4.4 7.6 4.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain HscB_4_cys PF18256.1 PFH33125.1 - 2 8.3 3.7 6.2 6.7 0.3 2.8 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif DUF63 PF01889.17 PFH33125.1 - 2.8 8.1 5.5 8.7 6.4 0.1 2.2 1 1 1 2 2 2 0 Membrane protein of unknown function DUF63 zf-C3HC4_4 PF15227.6 PFH33125.1 - 3.5 7.9 7.6 0.27 11.4 2.5 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Cytochrom_C PF00034.21 PFH33126.1 - 2.9e-08 34.8 0.0 4.9e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 PFH33126.1 - 0.00083 19.6 0.5 0.0018 18.5 0.5 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 PFH33126.1 - 0.002 17.9 0.0 0.027 14.2 0.0 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain PDEase_I PF00233.19 PFH33127.1 - 1.6e-49 168.8 0.2 2.7e-49 168.0 0.2 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.31 PFH33127.1 - 4.7e-11 42.4 10.2 4.7e-11 42.4 10.2 2.1 2 0 0 2 2 2 1 Ion transport protein MatE PF01554.18 PFH33127.1 - 0.48 10.1 7.8 3.5 7.3 1.5 2.5 2 0 0 2 2 2 0 MatE DA1-like PF12315.8 PFH33128.1 - 2.6e-09 36.8 0.0 5.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Protein DA1 LIM PF00412.22 PFH33129.1 - 0.0017 18.5 4.4 0.017 15.4 0.1 2.9 3 0 0 3 3 3 1 LIM domain CTU2 PF10288.9 PFH33129.1 - 0.014 15.6 3.5 0.46 10.7 0.3 2.4 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 YhfH PF14149.6 PFH33129.1 - 0.44 10.6 4.3 2.9 8.0 0.2 2.4 2 0 0 2 2 2 0 YhfH-like protein LRAT PF04970.13 PFH33130.1 - 5.3e-18 65.5 0.0 1e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF87 PF01935.17 PFH33130.1 - 0.2 11.8 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain MAR_sialic_bdg PF10564.9 PFH33131.1 - 0.058 13.4 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat AP2 PF00847.20 PFH33132.1 - 7.7e-05 22.9 2.7 0.014 15.6 0.5 2.5 2 0 0 2 2 2 2 AP2 domain TAL_FSA PF00923.19 PFH33133.1 - 2.6e-94 315.8 4.0 5.4e-93 311.5 4.0 2.0 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Tubulin_2 PF13809.6 PFH33133.1 - 0.029 13.6 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Tubulin like HEAT PF02985.22 PFH33134.1 - 5e-06 26.3 20.1 0.0057 16.8 0.1 7.9 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 PFH33134.1 - 4.2e-05 23.8 17.3 0.046 14.1 0.2 6.8 6 2 1 7 7 7 2 HEAT repeats Adaptin_N PF01602.20 PFH33134.1 - 0.0044 15.6 4.0 3.3 6.2 0.0 4.1 5 0 0 5 5 5 2 Adaptin N terminal region HEAT_EZ PF13513.6 PFH33134.1 - 1.8 9.2 14.1 11 6.7 0.6 5.8 5 0 0 5 5 5 0 HEAT-like repeat Hydrolase_3 PF08282.12 PFH33136.1 - 1.3e-50 172.5 0.0 1.7e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PFH33136.1 - 2.3e-14 53.5 0.0 2.9e-11 43.4 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 PFH33136.1 - 3.7e-05 24.1 0.6 0.025 14.9 0.0 3.3 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PFH33136.1 - 6.4e-05 23.1 0.1 0.0011 19.0 0.0 2.5 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PFH33137.1 - 6.3e-48 163.7 0.0 8.1e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PFH33137.1 - 1.5e-12 47.6 0.0 1.1e-08 34.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 PFH33137.1 - 2.1e-05 24.9 0.2 0.0039 17.5 0.0 2.9 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PFH33137.1 - 0.014 15.5 0.1 0.15 12.1 0.1 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Med14 PF08638.11 PFH33138.1 - 5.6e-07 29.2 0.2 9.3e-07 28.4 0.2 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 Kelch_4 PF13418.6 PFH33139.1 - 8.9e-37 124.9 0.8 3.6e-10 39.7 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 PFH33139.1 - 8.4e-30 102.5 0.6 5.1e-06 26.6 0.1 8.1 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 PFH33139.1 - 2.5e-27 94.2 0.5 3.4e-09 36.7 0.1 5.7 4 1 1 5 5 5 4 Kelch motif Kelch_5 PF13854.6 PFH33139.1 - 7.1e-27 92.9 0.2 0.0013 18.6 0.0 6.6 6 0 0 6 6 6 6 Kelch motif DUF4110 PF13422.6 PFH33139.1 - 8.6e-23 80.2 4.2 8.6e-23 80.2 4.2 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.25 PFH33139.1 - 9.8e-14 50.7 0.1 0.016 14.8 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 PFH33139.1 - 4.5e-13 48.6 14.6 0.00045 20.1 0.0 7.6 7 3 0 7 7 7 3 Kelch motif PPO1_DWL PF12142.8 PFH33139.1 - 0.027 14.3 0.1 0.027 14.3 0.1 2.0 2 0 0 2 2 2 0 Polyphenol oxidase middle domain Period_C PF12114.8 PFH33140.1 - 8.8 5.9 9.7 29 4.2 9.7 1.9 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Ribosomal_L28e PF01778.17 PFH33143.1 - 1.6e-24 86.8 2.5 1.9e-24 86.6 2.5 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family MCPsignal PF00015.21 PFH33143.1 - 0.024 14.5 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Torsin PF06309.11 PFH33143.1 - 0.038 14.1 0.1 0.05 13.7 0.1 1.2 1 0 0 1 1 1 0 Torsin LRR_9 PF14580.6 PFH33146.1 - 9e-62 207.6 0.5 1.1e-61 207.3 0.5 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PFH33146.1 - 1.6e-09 37.4 5.4 1.6e-09 37.4 1.3 2.9 3 1 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 PFH33146.1 - 3.2e-08 33.7 7.4 9.9e-06 25.8 1.1 3.5 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PFH33146.1 - 4.8 8.1 8.1 18 6.4 0.1 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat Cyclin_C PF02984.19 PFH33147.1 - 1.5e-06 28.3 0.1 4.3e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain EFF-AFF PF14884.6 PFH33147.1 - 0.19 9.8 0.0 0.29 9.2 0.0 1.1 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen Importin_rep_4 PF18808.1 PFH33148.1 - 2e-10 40.8 1.1 4.7e-08 33.2 0.1 4.8 4 0 0 4 4 4 1 Importin repeat Vac14_Fab1_bd PF12755.7 PFH33148.1 - 7.3e-10 39.3 6.5 0.23 12.1 0.1 7.3 6 2 2 8 8 8 3 Vacuolar 14 Fab1-binding region HEAT PF02985.22 PFH33148.1 - 8e-10 38.1 18.9 0.0019 18.3 0.0 10.3 11 0 0 11 11 9 2 HEAT repeat HEAT_2 PF13646.6 PFH33148.1 - 2.5e-09 37.4 25.9 2e-06 28.1 0.0 9.6 8 3 1 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 PFH33148.1 - 6.7e-09 36.1 22.4 1.8e-06 28.3 0.1 8.8 8 1 1 9 9 7 2 HEAT-like repeat Cnd1 PF12717.7 PFH33148.1 - 7.6e-07 29.3 1.5 1.4e-05 25.2 0.1 3.9 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 PFH33148.1 - 2.1e-06 27.8 2.0 1.5 8.7 0.1 6.3 5 2 0 5 5 5 2 Domain of unknown function (DUF3385) Arm PF00514.23 PFH33148.1 - 1.1e-05 25.3 12.6 7.1 6.8 0.0 9.0 10 0 0 10 10 9 1 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 PFH33148.1 - 0.00098 18.7 0.0 0.36 10.3 0.0 4.5 5 1 1 6 6 6 1 Tti2 family IBN_N PF03810.19 PFH33148.1 - 0.0064 16.4 0.2 0.12 12.3 0.2 3.4 2 1 0 2 2 2 1 Importin-beta N-terminal domain CTD_bind PF04818.13 PFH33148.1 - 0.011 16.5 3.7 0.95 10.3 0.4 4.6 2 2 0 2 2 2 0 RNA polymerase II-binding domain. UME PF08064.13 PFH33148.1 - 0.012 15.6 3.2 12 5.9 0.1 5.4 6 0 0 6 6 6 0 UME (NUC010) domain AAA_25 PF13481.6 PFH33148.1 - 0.032 13.8 2.0 0.35 10.4 0.0 3.3 4 0 0 4 4 4 0 AAA domain RTP1_C1 PF10363.9 PFH33148.1 - 0.12 12.6 0.8 3.2 8.0 0.1 4.0 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4042 PF13251.6 PFH33148.1 - 0.21 11.3 1.7 2.1 8.0 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) Importin_rep_6 PF18829.1 PFH33148.1 - 0.35 11.0 2.3 9.4 6.4 0.2 3.6 3 0 0 3 3 2 0 Importin repeat 6 MMS19_N PF14500.6 PFH33148.1 - 0.42 10.2 10.8 3.6 7.1 0.1 4.8 4 2 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Adaptin_N PF01602.20 PFH33148.1 - 1.4 7.3 11.0 0.044 12.3 0.2 3.5 4 0 0 4 4 4 0 Adaptin N terminal region Form_Nir_trans PF01226.17 PFH33151.1 - 1.7e-72 243.6 15.9 2.1e-72 243.3 15.9 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter DHHC PF01529.20 PFH33152.1 - 8.6e-19 68.0 1.2 8.6e-19 68.0 1.2 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase MFS_1 PF07690.16 PFH33153.1 - 6.8e-22 77.9 35.4 1.5e-21 76.7 29.4 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily FAM176 PF14851.6 PFH33153.1 - 0.33 10.6 1.0 0.79 9.4 0.1 2.0 2 0 0 2 2 2 0 FAM176 family MaoC_dehydratas PF01575.19 PFH33154.1 - 9.3e-23 80.1 0.0 1.6e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 PFH33154.1 - 0.0011 19.1 0.0 0.96 9.6 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase SPC25 PF06703.11 PFH33155.1 - 1e-11 44.9 0.0 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Pkinase PF00069.25 PFH33157.1 - 8e-38 130.3 0.0 2.1e-35 122.4 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33157.1 - 3.3e-13 49.5 0.0 1.8e-10 40.6 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 PFH33157.1 - 0.0017 18.3 1.5 0.0086 16.0 0.1 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Mak16 PF04874.14 PFH33157.1 - 0.034 14.8 2.3 0.049 14.2 0.7 2.1 2 0 0 2 2 2 0 Mak16 protein C-terminal region Kelch_3 PF13415.6 PFH33159.1 - 2.8e-32 110.4 13.8 1.9e-05 24.8 0.0 6.6 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 PFH33159.1 - 7.7e-25 86.2 9.6 0.0014 18.1 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 PFH33159.1 - 1.8e-24 85.2 4.7 5.8e-06 26.2 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 PFH33159.1 - 2.5e-23 81.8 17.4 4.2e-06 26.7 0.1 6.4 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 PFH33159.1 - 3.2e-21 74.8 14.5 0.00076 19.7 0.0 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_2 PF07646.15 PFH33159.1 - 1e-11 44.3 10.7 0.018 15.0 0.2 6.3 6 1 0 6 6 6 3 Kelch motif Atg14 PF10186.9 PFH33159.1 - 0.16 11.0 0.2 0.34 10.0 0.2 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NPA PF16469.5 PFH33159.1 - 2 9.0 4.6 34 5.0 4.6 2.5 1 1 0 1 1 1 0 Nematode polyprotein allergen ABA-1 zf_CCCH_4 PF18345.1 PFH33160.1 - 4e-07 29.9 15.3 0.00073 19.5 4.4 2.8 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 PFH33160.1 - 1.9e-06 27.6 17.7 0.0032 17.3 3.9 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PFH33160.1 - 9e-06 25.4 14.0 0.0018 18.1 4.4 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 PFH33160.1 - 0.03 15.0 7.6 1.7 9.4 1.1 2.4 1 1 1 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 PFH33160.1 - 0.07 13.4 1.6 0.13 12.4 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 PFH33160.1 - 0.1 13.1 5.1 6.1 7.5 1.2 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Gemini_AC4_5_2 PF08464.10 PFH33161.1 - 0.4 10.7 10.9 3.4e+02 1.3 0.0 6.9 8 0 0 8 8 8 0 Geminivirus AC4/5 conserved region UCH PF00443.29 PFH33164.1 - 9.6e-24 84.3 0.0 3.6e-23 82.4 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PFH33164.1 - 2.8e-08 33.7 1.4 0.063 12.8 0.1 3.4 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 PFH33164.1 - 0.018 15.6 0.0 0.92 10.2 0.0 2.5 2 0 0 2 2 2 0 DUSP domain Myosin_head PF00063.21 PFH33165.1 - 3.7e-179 597.2 0.0 4.7e-179 596.8 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Dynein_light PF01221.18 PFH33165.1 - 3.7e-09 36.8 0.0 0.0003 21.1 0.0 2.7 2 0 0 2 2 2 2 Dynein light chain type 1 RsgA_GTPase PF03193.16 PFH33165.1 - 0.05 13.5 0.1 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 PFH33165.1 - 0.15 11.3 0.1 0.4 9.9 0.1 1.7 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 PFH33165.1 - 0.22 11.6 0.4 0.56 10.2 0.1 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Peptidase_C14 PF00656.22 PFH33166.1 - 4.8e-05 23.4 0.0 7.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Caspase domain PAN_3 PF08277.12 PFH33166.1 - 0.1 12.5 0.3 0.42 10.5 0.3 2.0 1 0 0 1 1 1 0 PAN-like domain Radial_spoke PF04712.12 PFH33167.1 - 2.9e-15 56.2 0.2 1.8e-05 23.9 0.1 3.3 2 1 1 3 3 3 3 Radial spokehead-like protein AAA PF00004.29 PFH33168.1 - 4.8e-48 162.9 0.0 5.7e-43 146.5 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PFH33168.1 - 1.8e-06 27.8 0.0 7.6e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PFH33168.1 - 4e-05 23.6 0.6 0.088 12.8 0.1 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 PFH33168.1 - 7.8e-05 23.2 0.1 0.0078 16.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 PFH33168.1 - 0.0001 22.0 0.0 0.00044 20.0 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 PFH33168.1 - 0.00015 22.2 5.7 0.055 13.8 0.1 4.4 3 1 1 4 4 4 1 AAA ATPase domain TsaE PF02367.17 PFH33168.1 - 0.00029 20.9 0.3 0.079 13.0 0.0 2.8 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 PFH33168.1 - 0.00083 19.6 2.3 0.0048 17.2 0.2 3.1 3 1 0 3 3 1 1 AAA domain IstB_IS21 PF01695.17 PFH33168.1 - 0.0015 18.3 0.0 0.0045 16.7 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 PFH33168.1 - 0.0025 17.1 0.1 0.0093 15.2 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 PFH33168.1 - 0.0027 17.5 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 PFH33168.1 - 0.0032 17.6 0.0 0.023 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 PFH33168.1 - 0.0033 17.4 0.0 0.013 15.5 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 PFH33168.1 - 0.004 16.6 0.6 0.07 12.5 0.1 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 PFH33168.1 - 0.018 14.6 0.1 0.37 10.4 0.1 2.5 1 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 PFH33168.1 - 0.02 14.9 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PFH33168.1 - 0.033 14.4 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 PFH33168.1 - 0.034 14.5 0.0 0.46 10.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.26 PFH33168.1 - 0.035 13.8 0.1 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 PFH33168.1 - 0.044 13.1 0.8 0.81 9.0 0.1 2.2 2 0 0 2 2 2 0 KaiC DUF815 PF05673.13 PFH33168.1 - 0.087 12.0 0.1 4.3 6.4 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF815) SKI PF01202.22 PFH33168.1 - 0.21 11.7 0.0 34 4.5 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.16 PFH33168.1 - 0.21 11.0 0.1 0.39 10.1 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_2 PF07724.14 PFH33168.1 - 0.23 11.5 0.0 0.57 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_8 PF12780.7 PFH33168.1 - 0.24 10.7 0.0 6.5 6.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 AP2 PF00847.20 PFH33169.1 - 3.8e-20 71.9 1.4 9.6e-10 38.6 0.4 2.8 2 1 0 2 2 2 2 AP2 domain ACDC PF14733.6 PFH33169.1 - 3.1e-18 65.9 0.3 5.6e-18 65.1 0.3 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal Cnd1 PF12717.7 PFH33170.1 - 3.8e-17 62.8 2.2 4.6e-15 56.0 0.2 3.5 2 2 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 BUD22 PF09073.10 PFH33170.1 - 0.0024 17.3 13.8 0.0024 17.3 13.8 6.3 6 0 0 6 6 6 4 BUD22 DDHD PF02862.17 PFH33170.1 - 2.9 8.0 8.5 12 6.0 0.3 3.8 3 0 0 3 3 3 0 DDHD domain HEAT PF02985.22 PFH33170.1 - 8.7 6.9 12.0 67 4.1 0.0 5.8 5 0 0 5 5 5 0 HEAT repeat Tom22 PF04281.13 PFH33171.1 - 6.4e-05 22.8 0.1 7.8e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 CD20 PF04103.15 PFH33171.1 - 0.017 15.2 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 CD20-like family Methyltr_RsmB-F PF01189.17 PFH33172.1 - 1.8e-28 99.6 0.0 3.7e-20 72.4 0.0 3.9 3 1 0 3 3 3 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 PFH33172.1 - 0.0014 18.8 0.0 0.0066 16.6 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase AMA-1 PF02430.15 PFH33173.1 - 2e-57 195.2 0.1 2.6e-49 168.5 0.1 2.1 2 0 0 2 2 2 2 Apical membrane antigen 1 UNC-50 PF05216.13 PFH33175.1 - 6.2e-45 153.5 3.4 8.5e-45 153.0 3.4 1.1 1 0 0 1 1 1 1 UNC-50 family DUF1614 PF07758.11 PFH33175.1 - 0.045 13.8 4.4 1.9 8.5 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1614) FixP_N PF14715.6 PFH33175.1 - 1.2 8.9 3.7 32 4.4 0.0 2.6 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP MMR_HSR1 PF01926.23 PFH33176.1 - 0.013 15.5 0.0 3.4 7.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PFH33176.1 - 0.024 14.2 0.0 0.087 12.4 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PFH33176.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 PFH33176.1 - 1 9.7 4.9 1 9.7 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain zf-CCCH PF00642.24 PFH33178.1 - 1.4e-07 31.2 23.5 4.8e-06 26.3 4.1 3.5 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PFH33178.1 - 0.00013 21.8 7.6 0.00013 21.8 7.6 3.8 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_4 PF18044.1 PFH33178.1 - 0.0015 18.3 4.1 0.0015 18.3 4.1 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 PFH33178.1 - 0.0035 18.0 8.5 0.068 13.9 0.9 2.5 2 0 0 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 PFH33178.1 - 0.0072 16.5 12.3 0.048 13.9 7.3 2.3 1 1 1 2 2 2 2 Zinc-finger containing family RL10P_insert PF17777.1 PFH33179.1 - 6.7e-25 86.9 0.0 1.4e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 PFH33179.1 - 1.6e-08 34.6 0.0 2.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 ORC4_C PF14629.6 PFH33179.1 - 0.05 13.0 0.1 8.6 5.7 0.0 2.1 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus Thr_dehydrat_C PF00585.18 PFH33179.1 - 0.066 13.0 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 C-terminal regulatory domain of Threonine dehydratase TPR_1 PF00515.28 PFH33180.1 - 1.2e-07 31.2 9.4 0.017 14.9 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 PFH33180.1 - 1e-06 29.1 63.7 0.12 13.2 0.4 12.7 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 PFH33180.1 - 3.5e-06 27.4 62.2 0.00051 20.5 0.5 11.0 10 2 2 12 12 11 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH33180.1 - 0.00028 21.0 20.1 0.036 14.3 0.0 7.3 7 2 2 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PFH33180.1 - 0.0031 17.8 12.9 19 5.9 0.0 8.6 9 1 1 10 10 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 PFH33180.1 - 0.0032 17.5 0.0 0.0032 17.5 0.0 9.9 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 PFH33180.1 - 0.011 16.4 1.0 0.011 16.4 1.0 11.5 11 1 1 12 12 10 0 Tetratricopeptide repeat TPR_12 PF13424.6 PFH33180.1 - 0.094 13.0 0.1 0.094 13.0 0.1 10.9 11 1 1 12 12 12 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH33180.1 - 0.72 10.6 0.0 0.72 10.6 0.0 9.6 12 0 0 12 12 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 PFH33180.1 - 1.5 9.2 17.4 2.2 8.7 0.0 6.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 PFH33180.1 - 1.6 8.9 19.2 4.2 7.6 0.1 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat ABC_ATPase PF09818.9 PFH33181.1 - 1.7e-183 610.5 0.0 2.3e-183 610.1 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 PFH33181.1 - 2.3e-05 25.0 0.0 4.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 PFH33181.1 - 0.034 13.9 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain CRAL_TRIO PF00650.20 PFH33182.1 - 2.2e-07 30.7 0.0 3.1e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain TIC20 PF16166.5 PFH33183.1 - 0.00028 20.7 5.3 0.00054 19.8 5.3 1.5 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like CHDCT2 PF08074.11 PFH33183.1 - 0.061 13.5 1.4 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Peptidase_S64 PF08192.11 PFH33183.1 - 0.51 8.8 14.3 0.72 8.3 14.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 SOG2 PF10428.9 PFH33183.1 - 0.65 9.1 25.1 0.93 8.6 25.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 PFH33183.1 - 0.69 8.7 10.7 1 8.1 10.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PI3K_1B_p101 PF10486.9 PFH33183.1 - 0.85 7.3 8.2 1.2 6.9 8.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PAP1 PF08601.10 PFH33183.1 - 1.3 8.7 21.3 1.8 8.2 21.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.9 PFH33183.1 - 1.9 6.9 9.1 2.6 6.5 9.1 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 PFH33183.1 - 5.6 4.0 11.1 7.3 3.6 11.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM199X PF15814.5 PFH33183.1 - 5.6 5.9 11.2 12 4.9 11.2 1.5 1 0 0 1 1 1 0 Protein family FAM199X Condensin2nSMC PF12422.8 PFH33184.1 - 0.0023 18.1 0.0 0.0053 17.0 0.0 1.5 1 1 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 PFH33184.1 - 0.0059 16.8 12.7 0.33 11.3 0.1 5.4 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 PFH33184.1 - 0.019 15.0 0.0 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 PFH33184.1 - 0.12 12.7 0.0 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 PFH33184.1 - 0.62 10.6 9.1 2.3 8.8 0.1 5.1 3 1 1 4 4 4 0 HEAT-like repeat OPA3 PF07047.12 PFH33185.1 - 4.3e-14 52.4 0.2 2.2e-13 50.1 0.2 2.0 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) CaKB PF03185.15 PFH33185.1 - 0.19 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit ECM11 PF15463.6 PFH33185.1 - 0.54 10.8 2.4 1.4 9.5 2.4 1.7 1 0 0 1 1 1 0 Extracellular mutant protein 11 Hamartin PF04388.12 PFH33185.1 - 1.9 7.0 5.9 2.2 6.9 5.9 1.2 1 0 0 1 1 1 0 Hamartin protein SUR7 PF06687.12 PFH33186.1 - 0.16 11.6 0.4 0.19 11.3 0.4 1.1 1 0 0 1 1 1 0 SUR7/PalI family IMP2_N PF18590.1 PFH33187.1 - 2.7e-22 79.1 0.1 4e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 PFH33187.1 - 0.038 13.9 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Immune Mapped Protein 2 (IMP2) C-terminal domain S-methyl_trans PF02574.16 PFH33188.1 - 2.2e-48 165.4 0.0 1.7e-47 162.5 0.0 2.0 1 1 0 1 1 1 1 Homocysteine S-methyltransferase ADK PF00406.22 PFH33189.1 - 8.9e-38 129.8 0.0 3.1e-25 89.0 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 PFH33189.1 - 3.6e-25 89.0 0.0 7.1e-18 65.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 PFH33189.1 - 4.1e-06 27.4 0.1 0.00065 20.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PFH33189.1 - 0.00011 22.4 0.0 0.091 12.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 PFH33189.1 - 0.00065 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 PFH33189.1 - 0.0024 17.6 0.2 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Peptidase_M24 PF00557.24 PFH33190.1 - 2.9e-47 161.1 0.1 4.4e-47 160.5 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 ATP-cone PF03477.16 PFH33190.1 - 0.17 12.5 0.0 13 6.4 0.0 2.3 2 0 0 2 2 2 0 ATP cone domain PhoLip_ATPase_C PF16212.5 PFH33191.1 - 3.9e-43 148.0 17.0 3.9e-43 148.0 17.0 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PFH33191.1 - 6.1e-17 61.1 0.6 1.7e-16 59.7 0.6 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PFH33191.1 - 9.2e-08 32.6 0.4 0.00096 19.5 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PFH33191.1 - 6.1e-05 22.6 0.0 6.1e-05 22.6 0.0 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 PFH33191.1 - 8.1e-05 22.6 0.0 0.00076 19.5 0.0 2.5 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PFH33191.1 - 0.018 14.8 0.0 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SET PF00856.28 PFH33193.1 - 4.1e-20 72.9 0.8 5.5e-19 69.2 0.1 3.2 2 1 0 2 2 2 1 SET domain AWS PF17907.1 PFH33193.1 - 0.00024 21.1 5.0 0.00024 21.1 5.0 2.7 2 0 0 2 2 2 1 AWS domain PHD PF00628.29 PFH33193.1 - 0.00028 20.7 7.2 0.00028 20.7 7.2 5.4 5 1 1 6 6 6 3 PHD-finger Hist_deacetyl PF00850.19 PFH33196.1 - 5.8e-40 137.7 0.2 5.5e-39 134.4 0.1 2.4 2 1 0 2 2 2 1 Histone deacetylase domain NTP_transf_2 PF01909.23 PFH33197.1 - 0.00037 20.7 0.0 0.00072 19.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PDEase_I PF00233.19 PFH33198.1 - 2.7e-55 187.7 1.2 5.8e-30 104.8 0.0 3.2 3 0 0 3 3 3 3 3'5'-cyclic nucleotide phosphodiesterase WW PF00397.26 PFH33199.1 - 7.6e-15 54.7 15.0 5.6e-10 39.1 4.0 2.6 2 0 0 2 2 2 2 WW domain FF PF01846.19 PFH33199.1 - 1.7e-14 53.7 16.6 1.3e-09 38.0 0.0 4.8 5 0 0 5 5 5 3 FF domain TetR_C_11 PF16859.5 PFH33199.1 - 0.00048 20.4 0.2 0.0012 19.2 0.2 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DUF4519 PF15012.6 PFH33199.1 - 8.7 6.6 7.9 0.78 10.0 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) NTP_transferase PF00483.23 PFH33200.1 - 4e-47 160.9 0.0 1.5e-25 90.3 0.0 2.1 1 1 1 2 2 2 2 Nucleotidyl transferase Hexapep PF00132.24 PFH33200.1 - 1.8e-09 36.9 5.3 3.1e-06 26.7 0.4 3.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 PFH33200.1 - 2.3e-06 28.0 0.0 3.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 PFH33200.1 - 9.4e-06 25.3 0.7 9.4e-06 25.3 0.7 3.0 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 PFH33200.1 - 0.0086 15.1 0.0 0.29 10.0 0.0 2.3 2 1 0 2 2 2 1 L-fucokinase RRF PF01765.19 PFH33202.1 - 3.6e-26 92.1 0.0 3.6e-26 92.1 0.0 1.4 2 0 0 2 2 2 1 Ribosome recycling factor AAA_2 PF07724.14 PFH33203.1 - 4.6e-53 179.8 0.0 3.3e-51 173.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 PFH33203.1 - 7.7e-33 112.5 1.2 7.7e-33 112.5 1.2 2.6 2 1 0 2 2 1 1 AAA lid domain AAA PF00004.29 PFH33203.1 - 8.9e-26 90.9 0.0 4.2e-13 49.9 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 PFH33203.1 - 7.7e-21 74.0 0.1 5.1e-20 71.3 0.1 2.6 1 1 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 PFH33203.1 - 1.5e-16 60.6 0.0 3.4e-10 40.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 PFH33203.1 - 4e-15 55.7 0.8 6.9e-06 26.1 0.0 3.9 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 PFH33203.1 - 7.7e-12 45.9 7.2 1.5e-06 28.7 0.0 4.6 3 2 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 PFH33203.1 - 1.4e-09 38.3 0.2 0.0079 16.5 0.0 3.9 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 PFH33203.1 - 1.3e-08 34.7 0.0 2.6e-05 24.0 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain TniB PF05621.11 PFH33203.1 - 1.7e-07 30.8 0.1 0.0061 16.0 0.0 4.2 3 1 0 3 3 3 1 Bacterial TniB protein ATPase_2 PF01637.18 PFH33203.1 - 3.1e-07 30.5 0.6 0.72 9.7 0.0 3.8 2 2 0 3 3 3 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 PFH33203.1 - 1.7e-06 28.1 0.0 0.078 13.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain RuvB_N PF05496.12 PFH33203.1 - 5.5e-06 26.2 1.6 0.0087 15.8 0.0 3.8 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 PFH33203.1 - 5.8e-06 25.9 0.0 0.021 14.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 PFH33203.1 - 6.7e-06 26.7 0.0 0.068 13.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.13 PFH33203.1 - 2.7e-05 23.4 0.1 0.022 13.9 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 PFH33203.1 - 7.1e-05 22.3 0.0 0.25 10.7 0.0 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 PFH33203.1 - 9.5e-05 22.2 0.1 0.11 12.2 0.0 3.0 3 0 0 3 3 2 1 IstB-like ATP binding protein NTPase_1 PF03266.15 PFH33203.1 - 0.00015 21.7 0.8 1.5 8.7 0.0 4.1 4 0 0 4 4 4 1 NTPase RNA_helicase PF00910.22 PFH33203.1 - 0.00015 22.1 0.0 1.3 9.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 PFH33203.1 - 0.00018 21.1 1.9 0.089 12.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 PFH33203.1 - 0.00025 21.2 0.0 0.24 11.6 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 PFH33203.1 - 0.00033 20.6 0.0 0.68 9.8 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_33 PF13671.6 PFH33203.1 - 0.00059 20.0 0.0 0.63 10.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 PFH33203.1 - 0.0014 18.6 0.0 2.1 8.4 0.0 3.0 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 PFH33203.1 - 0.0021 18.0 0.2 3.6 7.5 0.0 3.1 3 1 0 3 3 2 1 RsgA GTPase Zeta_toxin PF06414.12 PFH33203.1 - 0.0027 17.0 0.1 0.47 9.7 0.0 3.6 4 0 0 4 4 4 1 Zeta toxin AAA_24 PF13479.6 PFH33203.1 - 0.0042 16.8 0.0 0.86 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 PFH33203.1 - 0.0044 16.9 0.0 0.64 9.9 0.0 3.6 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 PFH33203.1 - 0.0048 17.2 0.5 13 6.0 0.0 4.4 3 1 0 3 3 3 0 AAA domain DNA_pol3_delta2 PF13177.6 PFH33203.1 - 0.0079 16.0 0.0 0.28 11.0 0.0 2.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit ResIII PF04851.15 PFH33203.1 - 0.0081 16.2 0.0 0.7 9.9 0.0 3.5 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit DUF4763 PF15960.5 PFH33203.1 - 0.0094 15.3 7.5 0.032 13.5 3.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) AAA_19 PF13245.6 PFH33203.1 - 0.011 16.1 0.0 1.3 9.3 0.0 3.2 3 1 0 3 3 2 0 AAA domain AAA_17 PF13207.6 PFH33203.1 - 0.013 16.0 0.2 2.4 8.6 0.0 3.6 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 PFH33203.1 - 0.015 15.8 0.1 5.4 7.5 0.0 3.2 3 0 0 3 3 2 0 ABC transporter AAA_29 PF13555.6 PFH33203.1 - 0.052 13.3 0.0 8.7 6.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 PFH33203.1 - 0.055 13.2 0.0 1.9 8.2 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cytochrom_C_2 PF01322.20 PFH33203.1 - 0.12 13.3 2.6 1.6 9.7 0.1 2.7 2 0 0 2 2 2 0 Cytochrome C' MMR_HSR1 PF01926.23 PFH33203.1 - 0.12 12.4 0.0 8.9 6.4 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Nop16 PF09420.10 PFH33203.1 - 0.32 11.0 6.4 0.99 9.4 0.0 2.7 2 1 1 3 3 3 0 Ribosome biogenesis protein Nop16 DUF948 PF06103.11 PFH33203.1 - 0.4 11.0 4.2 27 5.1 0.1 3.7 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Phage_GP20 PF06810.11 PFH33203.1 - 3.1 7.6 7.8 8.4 6.2 1.4 3.1 2 1 1 3 3 3 0 Phage minor structural protein GP20 Pkinase PF00069.25 PFH33205.1 - 3.1e-61 207.1 0.0 3.8e-60 203.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33205.1 - 4.2e-27 95.1 0.0 6.6e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH33205.1 - 9.1e-05 21.9 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PFH33205.1 - 0.00059 18.7 0.0 0.058 12.2 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Pox_ser-thr_kin PF05445.11 PFH33205.1 - 0.19 10.7 0.1 0.29 10.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glu_cyclase_2 PF05096.12 PFH33206.1 - 3.1e-16 59.6 0.0 8.7e-11 41.7 0.0 3.2 3 0 0 3 3 3 2 Glutamine cyclotransferase Biotin_lipoyl_2 PF13533.6 PFH33206.1 - 0.079 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like DNA_pol_B PF00136.21 PFH33207.1 - 1.3e-138 462.6 0.3 1.7e-138 462.2 0.3 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 PFH33207.1 - 6.5e-55 186.6 0.0 1.3e-40 139.6 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 PFH33207.1 - 9e-18 64.5 8.8 2.1e-17 63.3 8.8 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 PFH33207.1 - 0.041 12.8 0.2 0.12 11.2 0.0 1.6 1 1 1 2 2 2 0 DNA polymerase type B, organellar and viral C1_1 PF00130.22 PFH33207.1 - 7.5 6.5 7.2 38 4.3 7.2 2.2 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Actin PF00022.19 PFH33208.1 - 1.2e-73 248.0 0.0 4.1e-36 124.5 0.0 2.9 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 PFH33208.1 - 0.00038 19.4 0.0 0.0022 16.9 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein SRP68 PF16969.5 PFH33210.1 - 4.7e-48 164.5 19.1 1.3e-40 140.0 11.3 2.7 2 1 0 2 2 2 2 RNA-binding signal recognition particle 68 Med3 PF11593.8 PFH33210.1 - 0.039 13.1 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Tox-REase-5 PF15648.6 PFH33210.1 - 0.2 12.2 0.9 1.4 9.5 0.2 2.2 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 Kinase-like PF14531.6 PFH33211.1 - 1.7e-44 152.3 0.0 1.4e-43 149.3 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH33211.1 - 7.9e-13 48.4 0.0 1.1e-11 44.6 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33211.1 - 8.5e-10 38.3 0.1 4.8e-09 35.9 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH33211.1 - 0.024 14.6 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 PFH33211.1 - 0.042 13.2 0.1 0.078 12.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PFH33211.1 - 0.066 12.0 0.0 0.33 9.7 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase GAS PF13851.6 PFH33212.1 - 1.5e-05 24.4 19.7 1.5e-05 24.4 19.7 6.7 3 2 2 5 5 5 1 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 PFH33212.1 - 0.0018 18.5 5.2 0.0018 18.5 5.2 7.8 4 1 3 8 8 8 2 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 PFH33212.1 - 0.0072 16.5 0.5 0.0072 16.5 0.5 8.5 9 1 2 11 11 11 3 Homeobox associated leucine zipper DUF1664 PF07889.12 PFH33212.1 - 0.46 10.5 31.9 0.12 12.4 5.2 5.6 4 2 0 5 5 5 0 Protein of unknown function (DUF1664) Scaffolding_pro PF11418.8 PFH33212.1 - 3.9 8.1 8.3 1.3 9.6 0.6 3.5 2 1 1 3 3 3 0 Phi29 scaffolding protein DUF948 PF06103.11 PFH33212.1 - 9.4 6.6 18.4 5.5 7.3 2.9 4.8 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) HALZ PF02183.18 PFH33213.1 - 0.00073 19.7 0.3 0.00073 19.7 0.3 6.5 6 0 0 6 6 6 3 Homeobox associated leucine zipper Shugoshin_N PF07558.11 PFH33213.1 - 0.45 10.4 7.9 0.31 10.9 0.3 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Sod_Ni PF09055.11 PFH33213.1 - 1.1 9.8 6.9 0.077 13.6 0.8 2.2 2 0 0 2 2 2 0 Nickel-containing superoxide dismutase ZnuA PF01297.17 PFH33213.1 - 1.6 8.1 10.4 0.35 10.3 7.0 1.7 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic CENP-F_leu_zip PF10473.9 PFH33213.1 - 1.7 8.7 83.2 0.015 15.4 11.1 5.8 2 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sdh5 PF03937.16 PFH33214.1 - 3.7e-17 62.1 0.0 9.7e-17 60.7 0.1 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase PIG-L PF02585.17 PFH33215.1 - 5e-19 69.2 0.1 1e-18 68.2 0.0 1.6 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase Pex2_Pex12 PF04757.14 PFH33216.1 - 2e-18 66.9 2.9 4e-18 65.8 2.9 1.5 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 PFH33216.1 - 0.075 12.9 5.3 0.19 11.6 1.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 PFH33216.1 - 0.19 11.9 0.2 0.19 11.9 0.2 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-C3HC4 PF00097.25 PFH33216.1 - 0.55 10.1 7.3 3 7.8 7.3 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 PFH33216.1 - 1.7 8.6 4.6 8.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ras PF00071.22 PFH33217.1 - 4.1e-64 215.1 0.6 4.9e-64 214.8 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH33217.1 - 1.8e-35 121.7 0.1 3.2e-35 121.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH33217.1 - 2.8e-15 56.2 0.0 3.6e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PFH33217.1 - 2.3e-06 27.6 0.0 4.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 PFH33217.1 - 2.3e-05 23.9 0.1 3.1e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PFH33217.1 - 5.3e-05 22.7 0.1 7e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PFH33217.1 - 5.5e-05 23.1 0.8 0.092 12.7 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PFH33217.1 - 0.00039 20.0 0.2 0.0012 18.5 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 PFH33217.1 - 0.027 14.7 0.0 0.044 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PFH33217.1 - 0.032 14.6 0.0 0.05 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 PFH33217.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_5 PF07728.14 PFH33217.1 - 0.11 12.5 0.1 0.29 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3873 PF12989.7 PFH33217.1 - 0.11 12.9 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) Proteasome PF00227.26 PFH33218.1 - 1.8e-53 180.9 0.7 2.2e-53 180.6 0.7 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PFH33218.1 - 2.5e-14 52.6 0.0 4.6e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Carb_kinase PF01256.17 PFH33219.1 - 1.3e-27 96.9 7.9 4.1e-21 75.6 0.1 3.9 3 1 0 3 3 3 3 Carbohydrate kinase LPAM_2 PF13627.6 PFH33219.1 - 0.13 12.1 1.2 0.48 10.3 1.2 2.0 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site ELMO_CED12 PF04727.13 PFH33221.1 - 9.2e-20 71.5 0.0 3.4e-18 66.4 0.0 2.4 2 0 0 2 2 2 1 ELMO/CED-12 family P33MONOX PF15302.6 PFH33221.1 - 8.2 6.0 6.6 14 5.3 6.6 1.2 1 0 0 1 1 1 0 P33 mono-oxygenase RNA_pol_Rpb2_6 PF00562.28 PFH33225.1 - 6.8e-122 407.3 0.0 9.2e-122 406.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 PFH33225.1 - 1.2e-59 201.2 0.0 1.6e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 PFH33225.1 - 1.8e-50 171.3 0.0 3.1e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 PFH33225.1 - 2.3e-33 114.4 0.5 5.4e-33 113.3 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 PFH33225.1 - 1.5e-25 89.1 0.0 3.6e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 PFH33225.1 - 1.5e-21 76.4 0.1 3.6e-21 75.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 PFH33225.1 - 2.1e-17 63.4 2.0 5.8e-17 62.0 2.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 SNF2_N PF00176.23 PFH33226.1 - 2.5e-53 181.0 0.1 4.9e-53 180.1 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PFH33226.1 - 1.2e-21 77.1 0.0 2.9e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 PFH33226.1 - 6.8e-16 57.9 0.7 4.9e-08 32.8 0.0 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.8 PFH33226.1 - 1.6e-08 34.1 0.2 3.3e-08 33.0 0.2 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 PFH33226.1 - 8.7e-06 25.8 0.0 2.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4208 PF13907.6 PFH33226.1 - 1.2e-05 25.7 0.0 5.1e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4208) DEAD PF00270.29 PFH33226.1 - 0.00046 20.0 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase CHDCT2 PF08074.11 PFH33226.1 - 0.0049 17.1 0.0 0.0049 17.1 0.0 3.2 3 0 0 3 3 3 1 CHDCT2 (NUC038) domain ERCC3_RAD25_C PF16203.5 PFH33226.1 - 0.0078 15.5 0.0 0.0078 15.5 0.0 1.7 2 0 0 2 2 1 1 ERCC3/RAD25/XPB C-terminal helicase CDH1_2_SANT_HL1 PF18375.1 PFH33226.1 - 0.012 16.3 0.0 0.012 16.3 0.0 3.0 3 0 0 3 3 2 0 CDH1/2 SANT-Helical linker 1 Cdh1_DBD_1 PF18196.1 PFH33226.1 - 0.03 14.6 4.1 0.05 13.9 0.0 3.3 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 SLIDE PF09111.10 PFH33226.1 - 0.11 12.6 0.0 0.52 10.3 0.0 2.2 1 0 0 1 1 1 0 SLIDE GCIP PF13324.6 PFH33226.1 - 0.9 9.1 10.8 0.33 10.5 0.3 2.9 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting MCU PF04678.13 PFH33228.1 - 0.099 12.7 1.9 0.3 11.2 1.9 1.8 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Pkinase PF00069.25 PFH33229.1 - 2.6e-11 43.4 0.0 4.3e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PFH33229.1 - 2.3e-06 27.2 0.0 4.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 PFH33229.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 PFH33229.1 - 0.062 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Elong-fact-P_C PF09285.11 PFH33230.1 - 4.8e-14 51.8 0.1 1.4e-13 50.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.12 PFH33230.1 - 8.2e-08 32.2 0.1 4.9e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 PFH33230.1 - 1.4e-07 31.4 0.6 2.1e-07 30.9 0.1 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain DnaJ PF00226.31 PFH33231.1 - 9e-28 96.2 2.4 1.4e-27 95.6 2.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 PFH33231.1 - 2.4e-12 47.2 0.0 3.4e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 PFH33231.1 - 0.0078 16.5 4.3 0.013 15.8 4.3 1.3 1 0 0 1 1 1 1 DnaJ central domain TB PF00683.17 PFH33231.1 - 0.017 14.9 0.3 0.036 13.8 0.3 1.5 1 0 0 1 1 1 0 TB domain PA14 PF07691.12 PFH33232.1 - 2.5e-24 85.8 0.0 4.5e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 PA14 domain LCCL PF03815.19 PFH33232.1 - 3.4e-16 59.1 0.1 9.4e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 LCCL domain F5_F8_type_C PF00754.25 PFH33232.1 - 9.6e-08 32.2 0.1 1.7e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 F5/8 type C domain GLEYA PF10528.9 PFH33232.1 - 0.00082 19.8 0.0 0.005 17.2 0.0 2.4 3 0 0 3 3 3 1 GLEYA domain Myosin_tail_1 PF01576.19 PFH33232.1 - 0.36 8.6 0.5 0.46 8.2 0.5 1.0 1 0 0 1 1 1 0 Myosin tail G-patch PF01585.23 PFH33239.1 - 0.0013 18.6 0.3 0.0036 17.1 0.3 1.7 1 0 0 1 1 1 1 G-patch domain Glyco_hydro_88 PF07470.13 PFH33239.1 - 0.12 11.4 0.4 0.2 10.7 0.4 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 DivIVA PF05103.13 PFH33239.1 - 0.29 11.2 7.6 1.2 9.2 7.6 2.2 1 0 0 1 1 1 0 DivIVA protein DUF4407 PF14362.6 PFH33239.1 - 0.67 9.3 24.9 0.27 10.5 10.4 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Nsp1_C PF05064.13 PFH33239.1 - 2.8 7.7 5.1 3.2 7.6 0.3 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF4140 PF13600.6 PFH33239.1 - 5.9 7.4 18.6 15 6.1 0.2 4.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) RRP7 PF12923.7 PFH33240.1 - 4e-17 62.5 14.9 8.1e-16 58.2 14.9 2.4 1 1 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain AIP3 PF03915.13 PFH33240.1 - 0.00089 18.5 0.7 0.042 12.9 0.0 2.3 2 0 0 2 2 2 2 Actin interacting protein 3 DUF5093 PF17011.5 PFH33240.1 - 0.023 15.0 0.2 0.023 15.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) PDEase_I PF00233.19 PFH33241.1 - 2.2e-52 178.2 1.3 3.6e-52 177.5 1.3 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.31 PFH33241.1 - 3.3e-10 39.6 5.2 6.9e-10 38.6 3.3 2.2 2 0 0 2 2 2 1 Ion transport protein WD40 PF00400.32 PFH33242.1 - 5.2e-13 49.2 4.0 3.1e-06 27.8 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat BUD22 PF09073.10 PFH33242.1 - 0.0077 15.6 0.1 0.016 14.5 0.1 1.5 1 0 0 1 1 1 1 BUD22 WD40 PF00400.32 PFH33243.1 - 6.4e-40 134.4 16.8 0.00026 21.7 0.1 12.7 14 0 0 14 14 14 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH33243.1 - 6e-16 58.5 0.0 0.15 12.4 0.0 7.4 4 2 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PFH33243.1 - 3.1e-07 30.0 0.0 0.16 11.3 0.0 4.0 4 0 0 4 4 4 2 WD40-like domain PQQ_2 PF13360.6 PFH33243.1 - 2.6e-05 23.9 0.0 0.48 10.0 0.0 3.3 1 1 2 3 3 3 3 PQQ-like domain Ge1_WD40 PF16529.5 PFH33243.1 - 0.044 12.8 0.0 45 2.8 0.0 3.8 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 PFH33243.1 - 0.076 13.5 2.1 13 6.5 0.0 5.0 6 1 1 7 7 7 0 PQQ-like domain His_Phos_1 PF00300.22 PFH33244.1 - 1.8e-11 44.1 0.0 6.9e-09 35.7 0.0 2.8 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Zn_ribbon_17 PF17120.5 PFH33244.1 - 1.2 8.8 6.4 7.3 6.3 6.4 2.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SAG PF04092.13 PFH33245.1 - 4.7e-23 82.4 13.4 7.6e-13 49.4 1.4 2.2 2 0 0 2 2 2 2 SRS domain DND1_DSRM PF14709.7 PFH33245.1 - 0.011 16.0 0.3 0.029 14.6 0.3 1.8 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Dpy-30 PF05186.13 PFH33247.1 - 0.0013 18.4 0.1 0.0026 17.4 0.1 1.6 1 0 0 1 1 1 1 Dpy-30 motif Kinase-like PF14531.6 PFH33248.1 - 9e-33 113.8 0.0 1.2e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH33248.1 - 2.8e-22 79.4 0.0 1.1e-21 77.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33248.1 - 7.1e-09 35.3 0.0 1.4e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 PFH33248.1 - 0.022 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH33248.1 - 0.087 12.7 0.0 0.73 9.7 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PFH33248.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Lactamase_B_2 PF12706.7 PFH33249.1 - 1e-05 25.2 0.0 0.0015 18.1 0.0 2.6 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PFH33249.1 - 0.0015 18.6 0.2 0.0055 16.7 0.0 2.1 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily RRM_1 PF00076.22 PFH33250.1 - 1.1e-05 25.2 0.1 2.1e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 PFH33250.1 - 0.024 14.5 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Toxin_12 PF07740.12 PFH33251.1 - 0.02 15.6 4.6 0.035 14.8 4.6 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin Toxin_29 PF08116.11 PFH33251.1 - 0.16 12.0 2.9 0.33 11.0 2.9 1.5 1 0 0 1 1 1 0 PhTx neurotoxin family Toxin_23 PF08093.11 PFH33251.1 - 0.85 9.8 4.7 1.5 9.0 4.7 1.4 1 0 0 1 1 1 0 Magi 5 toxic peptide family FKBP_C PF00254.28 PFH33252.1 - 4.1e-11 43.0 0.0 6.8e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase Inhibitor_I78 PF11720.8 PFH33252.1 - 0.049 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I78 family IF3_N PF05198.16 PFH33253.1 - 0.027 14.7 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 PFH33253.1 - 0.028 14.4 0.1 0.047 13.7 0.1 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain ADK PF00406.22 PFH33254.1 - 4.9e-19 68.9 0.1 1.2e-06 28.7 0.0 3.1 3 0 0 3 3 3 3 Adenylate kinase AAA_17 PF13207.6 PFH33254.1 - 2.3e-12 47.5 0.8 1.6e-07 31.9 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 PFH33254.1 - 4e-07 30.6 0.2 1.5e-05 25.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PFH33254.1 - 8.8e-06 25.9 0.4 9.4e-05 22.6 0.0 2.8 2 2 1 3 3 3 1 AAA domain Cytidylate_kin PF02224.18 PFH33254.1 - 0.0031 17.3 0.3 0.0077 16.0 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase KTI12 PF08433.10 PFH33254.1 - 0.014 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF1180 PF06679.12 PFH33254.1 - 1.2 9.5 8.7 19 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Ferrochelatase PF00762.19 PFH33255.1 - 1.6e-77 260.7 0.0 6.7e-63 212.7 0.0 3.0 3 0 0 3 3 3 2 Ferrochelatase CbiX PF01903.17 PFH33255.1 - 0.078 13.3 0.0 15 6.0 0.0 2.7 2 0 0 2 2 2 0 CbiX CbtB PF09489.10 PFH33256.1 - 2 8.6 4.0 31 4.8 0.4 2.4 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) TBP PF00352.21 PFH33258.1 - 2.5e-50 168.4 0.0 1.2e-25 89.2 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 PFH33258.1 - 0.00077 19.5 0.0 0.0081 16.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3378) Aminotran_1_2 PF00155.21 PFH33259.1 - 1.1e-68 232.0 0.0 2.2e-68 231.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 PFH33259.1 - 0.001 18.4 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 PFH33259.1 - 0.0011 18.0 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 PFH33259.1 - 0.0059 15.2 0.0 0.0098 14.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MFS_1 PF07690.16 PFH33260.1 - 2.4e-26 92.5 36.7 2.4e-26 92.5 36.7 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 PFH33260.1 - 1.7e-08 33.2 19.8 3.9e-06 25.4 6.4 3.1 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Tcp10_C PF07202.13 PFH33261.1 - 6.7e-16 58.7 0.0 1.3e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 T-complex protein 10 C-terminus FapA PF03961.13 PFH33261.1 - 4.6 5.7 9.2 7.4 5.0 9.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 PFH33261.1 - 8 5.2 29.1 19 4.0 28.9 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.12 PFH33261.1 - 8.5 6.8 22.6 1.6 9.2 17.4 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ubiquitin PF00240.23 PFH33262.1 - 1e-06 28.4 0.1 2.5e-06 27.2 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 PFH33262.1 - 3.8e-05 24.1 0.0 0.00017 22.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 PFH33262.1 - 0.084 12.7 0.1 0.61 10.0 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Pkinase PF00069.25 PFH33263.1 - 4.7e-20 72.0 0.0 1.1e-16 61.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 PFH33263.1 - 1.6e-14 53.9 0.0 7.8e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.17 PFH33263.1 - 5.8e-05 22.5 0.0 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 PFH33263.1 - 0.0089 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PFH33263.1 - 0.062 12.9 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 RIO1 family DUF5082 PF16888.5 PFH33264.1 - 8.2e-05 22.9 2.4 0.18 12.1 0.3 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF5082) Troponin PF00992.20 PFH33264.1 - 0.00014 22.2 0.8 0.0002 21.7 0.8 1.1 1 0 0 1 1 1 1 Troponin MIS13 PF08202.11 PFH33264.1 - 0.00084 18.7 0.4 0.0011 18.3 0.4 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Baculo_PEP_C PF04513.12 PFH33264.1 - 0.0021 18.1 0.3 0.0055 16.7 0.2 1.5 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus GOLGA2L5 PF15070.6 PFH33264.1 - 0.0086 14.8 0.5 0.01 14.6 0.5 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DUF2130 PF09903.9 PFH33264.1 - 0.012 15.0 1.2 0.24 10.6 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) TMCO5 PF14992.6 PFH33264.1 - 0.012 15.3 1.0 0.015 14.9 1.0 1.1 1 0 0 1 1 1 0 TMCO5 family CdvA PF18822.1 PFH33264.1 - 0.015 15.1 1.1 0.06 13.2 0.2 1.9 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Jnk-SapK_ap_N PF09744.9 PFH33264.1 - 0.016 15.5 3.0 0.069 13.4 3.0 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 ApoLp-III PF07464.11 PFH33264.1 - 0.017 15.3 1.2 0.018 15.1 0.3 1.5 2 0 0 2 2 1 0 Apolipophorin-III precursor (apoLp-III) DUF4455 PF14643.6 PFH33264.1 - 0.017 13.8 0.4 0.021 13.5 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) MukF_M PF17192.4 PFH33264.1 - 0.031 14.0 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 MukF middle domain DUF773 PF05600.12 PFH33264.1 - 0.038 12.7 0.8 0.047 12.4 0.8 1.0 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 RasGAP_C PF03836.15 PFH33264.1 - 0.041 14.0 1.0 0.065 13.4 0.3 1.6 2 0 0 2 2 2 0 RasGAP C-terminus DUF4795 PF16043.5 PFH33264.1 - 0.051 13.2 1.1 0.066 12.8 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Apolipoprotein PF01442.18 PFH33264.1 - 0.053 13.4 1.0 0.1 12.5 1.0 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HemX PF04375.14 PFH33264.1 - 0.054 12.8 0.1 0.07 12.4 0.1 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase CLZ PF16526.5 PFH33264.1 - 0.057 13.8 2.4 0.18 12.2 1.0 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4618 PF15397.6 PFH33264.1 - 0.079 12.4 3.1 0.28 10.5 1.1 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) LPP PF04728.13 PFH33264.1 - 0.083 13.3 1.6 6.4 7.3 0.6 2.5 2 1 0 2 2 2 0 Lipoprotein leucine-zipper PigN PF04987.14 PFH33264.1 - 0.083 11.7 0.2 0.11 11.3 0.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF883 PF05957.13 PFH33264.1 - 0.093 13.3 0.1 0.17 12.5 0.1 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Thioredoxin_2 PF13098.6 PFH33264.1 - 0.11 13.0 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain PspA_IM30 PF04012.12 PFH33264.1 - 0.11 12.0 4.4 0.41 10.2 0.9 2.0 2 0 0 2 2 2 0 PspA/IM30 family DUF948 PF06103.11 PFH33264.1 - 0.12 12.6 1.2 0.26 11.6 0.2 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_Mu_Gam PF07352.12 PFH33264.1 - 0.12 12.3 1.5 0.17 11.8 0.2 1.7 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Prefoldin_2 PF01920.20 PFH33264.1 - 0.12 12.3 2.9 0.69 9.9 2.9 1.9 1 1 0 1 1 1 0 Prefoldin subunit H-kinase_dim PF02895.14 PFH33264.1 - 0.13 12.7 0.1 0.27 11.7 0.1 1.6 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain TINF2_N PF14973.6 PFH33264.1 - 0.14 12.5 0.5 0.25 11.7 0.5 1.4 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus Rootletin PF15035.6 PFH33264.1 - 0.2 11.7 1.4 0.47 10.4 0.1 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion ACCA PF03255.14 PFH33264.1 - 0.23 11.3 2.6 4.4 7.2 0.3 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Cytochrom_B562 PF07361.11 PFH33264.1 - 1.4 9.6 4.5 2.3 8.9 1.0 1.9 1 1 1 2 2 2 0 Cytochrome b562 eIF2A PF08662.11 PFH33265.1 - 2.3e-56 190.8 0.0 3.7e-55 186.8 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CopK PF11525.8 PFH33265.1 - 0.058 13.0 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Copper resistance protein K Hydrolase_4 PF12146.8 PFH33266.1 - 1.9e-05 24.0 0.0 0.11 11.8 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PFH33266.1 - 0.0074 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 PFH33266.1 - 0.033 14.8 5.3 0.061 13.9 4.6 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.13 PFH33266.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PSS PF03034.15 PFH33268.1 - 9.4e-112 373.2 3.7 1.4e-111 372.6 3.7 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase SPX PF03105.19 PFH33269.1 - 0.018 15.0 0.3 0.027 14.4 0.3 1.2 1 0 0 1 1 1 0 SPX domain Ribosomal_S10 PF00338.22 PFH33269.1 - 0.062 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e LSM PF01423.22 PFH33270.1 - 1.8e-18 66.0 0.3 2e-18 65.8 0.3 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PFH33270.1 - 2.8e-06 27.4 0.0 3.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 PFH33270.1 - 0.041 14.0 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain DUF2642 PF10842.8 PFH33270.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) Rtt106 PF08512.12 PFH33271.1 - 1.2e-24 86.5 0.5 2.4e-23 82.4 0.0 2.6 1 1 1 2 2 2 1 Histone chaperone Rttp106-like POB3_N PF17292.2 PFH33271.1 - 1.4e-24 86.3 0.1 2e-23 82.6 0.1 2.4 2 0 0 2 2 2 1 POB3-like N-terminal PH domain SSrecog PF03531.14 PFH33271.1 - 1.9e-23 82.1 0.0 7.2e-23 80.3 0.0 2.1 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) YL1 PF05764.13 PFH33271.1 - 0.0036 17.5 32.9 0.0053 16.9 32.9 1.2 1 0 0 1 1 1 1 YL1 nuclear protein BUD22 PF09073.10 PFH33271.1 - 0.034 13.5 26.0 0.049 13.0 26.0 1.2 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.12 PFH33271.1 - 1.5 8.5 10.5 2.4 7.9 10.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 PFH33271.1 - 1.9 6.6 27.9 2.4 6.3 27.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 PFH33271.1 - 6.5 6.1 32.1 9.4 5.5 32.1 1.2 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 PFH33271.1 - 8.4 6.0 20.8 14 5.3 20.8 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PNISR PF15996.5 PFH33273.1 - 0.00044 20.6 0.0 0.00044 20.6 0.0 6.9 3 3 1 5 5 5 1 Arginine/serine-rich protein PNISR Arm PF00514.23 PFH33274.1 - 2.4e-13 49.6 0.0 3.6e-05 23.7 0.0 4.4 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PFH33274.1 - 0.0085 16.5 1.7 0.35 11.3 0.1 2.7 2 1 0 2 2 2 1 HEAT repeats Arm_3 PF16186.5 PFH33274.1 - 0.03 13.9 1.6 1.8 8.2 0.0 3.2 2 1 1 3 3 3 0 Atypical Arm repeat DUF2621 PF11084.8 PFH33275.1 - 0.0045 17.0 0.0 0.0049 16.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2621) PTCRA PF15028.6 PFH33275.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.0 1 0 0 1 1 1 0 Pre-T-cell antigen receptor DUF533 PF04391.12 PFH33276.1 - 0.026 14.1 0.1 0.05 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DnaJ PF00226.31 PFH33278.1 - 2.2e-06 27.7 0.1 6.4e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain DIX PF00778.17 PFH33278.1 - 1.9e-05 24.4 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 DIX domain Cnl2_NKP2 PF09447.10 PFH33278.1 - 0.043 14.0 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 Cnl2/NKP2 family protein Exonuc_VII_L PF02601.15 PFH33278.1 - 0.043 13.4 3.3 0.067 12.7 3.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_Mu_Gam PF07352.12 PFH33278.1 - 0.13 12.2 2.0 0.21 11.5 2.0 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein BTD PF09270.10 PFH33279.1 - 0.2 11.9 0.0 0.35 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain DUF5451 PF17532.2 PFH33279.1 - 5.7 7.2 12.2 2.4 8.4 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5451) Ribosomal_S8 PF00410.19 PFH33281.1 - 4.5e-18 65.4 0.0 5.3e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 F-box-like PF12937.7 PFH33282.1 - 0.0075 16.1 0.5 0.023 14.6 0.5 1.9 1 0 0 1 1 1 1 F-box-like BNIP2 PF12496.8 PFH33282.1 - 0.26 11.7 0.7 3.7 8.0 0.7 2.5 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 JmjC PF02373.22 PFH33283.1 - 3.8e-21 75.7 0.0 6.2e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 PFH33283.1 - 1.2e-19 71.1 0.0 2.5e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 PFH33283.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein SR-25 PF10500.9 PFH33283.1 - 0.046 13.3 13.0 0.16 11.6 2.8 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cupin_2 PF07883.11 PFH33283.1 - 0.17 11.6 0.0 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 Cupin domain Histone_H2A_C PF16211.5 PFH33284.1 - 5.2e-19 67.7 0.5 5.2e-19 67.7 0.5 1.8 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 PFH33284.1 - 9.8e-16 58.3 0.0 1.3e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PFH33284.1 - 7.6e-05 22.9 0.0 0.0001 22.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PFH33285.1 - 8.6e-55 184.7 1.6 9.6e-55 184.5 1.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PFH33285.1 - 9.1e-05 23.1 1.1 0.00011 22.8 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PFH33285.1 - 0.00046 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PFH33285.1 - 0.00046 20.3 0.4 0.00072 19.6 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PFH33285.1 - 0.0066 16.7 0.5 0.01 16.1 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PFH33285.1 - 0.016 15.3 0.1 0.027 14.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Ank_2 PF12796.7 PFH33286.1 - 3e-42 143.1 1.9 6.6e-16 58.7 0.5 5.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PFH33286.1 - 4.9e-33 109.4 3.5 1.7e-05 24.9 0.1 10.3 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 PFH33286.1 - 5.1e-31 106.3 3.0 7.9e-10 38.8 1.1 7.6 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 PFH33286.1 - 3e-28 97.0 3.0 5.4e-06 26.6 0.1 9.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 PFH33286.1 - 1.8e-27 95.3 4.0 8.4e-08 32.6 0.1 7.8 3 2 6 9 9 9 6 Ankyrin repeats (many copies) MTBP_C PF14920.6 PFH33286.1 - 0.58 9.8 3.7 1.8 8.3 3.7 1.7 1 0 0 1 1 1 0 MDM2-binding Spt4 PF06093.13 PFH33287.1 - 5.6e-30 103.3 0.4 7.4e-30 102.9 0.4 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-C2HC5 PF06221.13 PFH33287.1 - 0.066 13.2 0.2 0.51 10.4 0.1 2.1 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type PCI PF01399.27 PFH33288.1 - 6.9e-19 68.3 0.2 5.3e-18 65.5 0.0 2.5 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 PFH33288.1 - 3.2e-10 40.0 0.1 8.7e-10 38.5 0.1 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain TPR_19 PF14559.6 PFH33288.1 - 0.071 13.6 0.1 0.38 11.3 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 PFH33289.1 - 3.8e-52 177.1 0.0 4.9e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ephrin_rec_like PF07699.13 PFH33290.1 - 4e-33 112.9 112.5 1.5e-09 37.4 6.0 13.3 11 1 1 12 12 12 9 Putative ephrin-receptor like Kringle PF00051.18 PFH33290.1 - 1.1e-14 54.5 7.5 5.5e-14 52.2 7.5 2.3 1 0 0 1 1 1 1 Kringle domain MAR_sialic_bdg PF10564.9 PFH33290.1 - 0.001 19.1 0.7 0.001 19.1 0.7 3.7 3 0 0 3 3 3 2 Sialic-acid binding micronemal adhesive repeat TPT PF03151.16 PFH33291.1 - 2.8e-96 322.3 17.0 3.2e-96 322.1 17.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PFH33291.1 - 2e-09 37.7 26.6 3.7e-05 23.9 7.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PFH33291.1 - 2.1e-06 27.2 12.8 3.6e-06 26.4 12.8 1.4 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 PFH33291.1 - 0.43 9.7 10.4 2.8 7.0 3.2 2.7 1 1 0 2 2 2 0 Nucleotide-sugar transporter Diphthamide_syn PF01866.17 PFH33292.1 - 2.1e-93 313.1 0.0 6.5e-50 170.3 0.0 2.4 2 1 0 2 2 2 2 Putative diphthamide synthesis protein RNB PF00773.19 PFH33293.1 - 1.1e-94 317.4 0.0 2.1e-94 316.6 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 PFH33293.1 - 2.2e-16 59.6 0.0 4.2e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_S1 PF17215.3 PFH33293.1 - 3.5e-09 36.5 0.1 8.6e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 PFH33293.1 - 1.5e-07 31.4 0.1 0.00012 22.2 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 PFH33293.1 - 1.2e-05 25.0 0.0 3.3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Rrp44-like cold shock domain S1 PF00575.23 PFH33293.1 - 0.011 16.1 0.1 0.028 14.8 0.1 1.8 1 0 0 1 1 1 0 S1 RNA binding domain Pyr_redox_2 PF07992.14 PFH33294.1 - 8.8e-15 54.7 0.0 1.9e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PFH33294.1 - 0.00037 20.7 0.0 0.0009 19.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PFH33294.1 - 0.015 15.3 0.0 0.062 13.3 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 PFH33294.1 - 0.02 14.2 0.0 0.049 12.9 0.0 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 PFH33294.1 - 0.055 12.2 0.0 0.079 11.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 PFH33294.1 - 0.057 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 PFH33294.1 - 0.07 12.4 0.0 0.67 9.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PFH33294.1 - 0.086 13.4 0.0 11 6.7 0.1 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 PFH33294.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase AAA_6 PF12774.7 PFH33295.1 - 1.2e-146 487.9 0.0 2.2e-142 473.9 0.0 4.2 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PFH33295.1 - 2.7e-94 316.5 3.7 2.7e-94 316.5 3.7 3.6 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PFH33295.1 - 4.5e-92 308.0 0.0 1.4e-90 303.1 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PFH33295.1 - 1.5e-80 270.7 0.4 2.8e-79 266.5 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PFH33295.1 - 1.6e-79 266.1 3.8 1.6e-79 266.1 3.8 2.3 2 0 0 2 2 1 1 ATP-binding dynein motor region MT PF12777.7 PFH33295.1 - 8.1e-78 261.8 15.0 1.3e-77 261.1 15.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 PFH33295.1 - 6.4e-68 227.8 0.0 2.1e-61 206.6 0.0 4.2 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PFH33295.1 - 8.5e-49 165.5 3.8 8.7e-48 162.2 0.0 2.9 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PFH33295.1 - 7.8e-34 116.3 0.0 2.2e-31 108.4 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Kelch_4 PF13418.6 PFH33295.1 - 2.7e-26 91.3 4.7 1.5e-07 31.3 0.1 6.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Dynein_AAA_lid PF17852.1 PFH33295.1 - 1.4e-22 80.2 0.3 9.8e-22 77.4 0.3 2.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PFH33295.1 - 1.8e-22 79.8 0.0 2.9e-11 43.5 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PFH33295.1 - 4.1e-22 78.3 0.3 1.9e-21 76.2 0.2 2.2 2 0 0 2 2 1 1 AAA+ lid domain Kelch_5 PF13854.6 PFH33295.1 - 1.6e-21 75.8 0.2 0.00028 20.8 0.0 6.6 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 PFH33295.1 - 5.5e-16 58.4 14.2 3.5e-05 24.0 0.1 7.5 8 0 0 8 8 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 PFH33295.1 - 5.7e-16 57.8 1.0 6.9e-08 31.9 0.0 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 PFH33295.1 - 6e-16 58.1 0.9 4.8e-05 23.5 0.0 5.1 5 0 0 5 5 4 2 Kelch motif Filamin PF00630.19 PFH33295.1 - 2.4e-13 50.8 0.0 5.3e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Filamin/ABP280 repeat Kelch_2 PF07646.15 PFH33295.1 - 1.2e-10 40.9 7.6 0.00038 20.3 0.1 5.6 6 0 0 6 6 6 2 Kelch motif AAA_16 PF13191.6 PFH33295.1 - 2e-07 31.6 1.1 0.27 11.6 0.0 5.2 4 0 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 PFH33295.1 - 4.1e-07 30.3 1.2 0.59 10.4 0.0 5.4 5 0 0 5 5 4 1 AAA domain AAA_18 PF13238.6 PFH33295.1 - 3.7e-06 27.5 3.7 0.1 13.1 0.0 4.5 5 0 0 5 5 3 1 AAA domain AAA PF00004.29 PFH33295.1 - 4.6e-06 27.1 0.0 0.7 10.3 0.0 4.8 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) TIG PF01833.24 PFH33295.1 - 4.5e-05 23.4 0.1 0.0001 22.3 0.1 1.6 1 0 0 1 1 1 1 IPT/TIG domain IstB_IS21 PF01695.17 PFH33295.1 - 0.00027 20.7 0.1 1 9.0 0.0 3.5 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_33 PF13671.6 PFH33295.1 - 0.00038 20.6 0.3 3.7 7.7 0.0 4.4 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.6 PFH33295.1 - 0.00066 19.4 0.1 2.2 8.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 PFH33295.1 - 0.00067 20.2 0.0 0.8 10.2 0.0 4.2 3 0 0 3 3 3 1 ABC transporter Sigma54_activat PF00158.26 PFH33295.1 - 0.0015 18.3 0.0 1.4 8.6 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain RNA_helicase PF00910.22 PFH33295.1 - 0.0018 18.7 0.2 15 6.0 0.0 4.1 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.6 PFH33295.1 - 0.0028 18.0 1.5 4.7 7.5 0.0 4.5 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 PFH33295.1 - 0.0099 15.8 0.3 2.1 8.2 0.0 3.7 4 0 0 4 4 3 1 NACHT domain TsaE PF02367.17 PFH33295.1 - 0.014 15.4 0.4 4.3 7.3 0.0 3.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 PFH33295.1 - 0.023 14.1 0.6 22 4.4 0.0 3.8 4 0 0 4 4 4 0 PhoH-like protein Cytidylate_kin PF02224.18 PFH33295.1 - 0.051 13.3 3.1 1.2 8.8 0.0 3.2 3 0 0 3 3 2 0 Cytidylate kinase EAP30 PF04157.16 PFH33295.1 - 0.056 12.7 3.7 0.14 11.4 1.1 2.6 2 0 0 2 2 2 0 EAP30/Vps36 family HD_3 PF13023.6 PFH33295.1 - 0.06 13.3 1.6 0.22 11.4 1.6 2.0 1 0 0 1 1 1 0 HD domain Viral_helicase1 PF01443.18 PFH33295.1 - 0.073 12.8 0.0 4.5 7.0 0.0 2.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NitrOD5 PF11537.8 PFH33295.1 - 0.13 12.4 0.0 17 5.6 0.0 3.4 2 0 0 2 2 2 0 Nitrosopumilus output domain 5 Sigma54_activ_2 PF14532.6 PFH33295.1 - 0.13 12.4 0.0 11 6.1 0.0 3.3 2 0 0 2 2 2 0 Sigma-54 interaction domain ATP_bind_1 PF03029.17 PFH33295.1 - 0.16 11.8 0.2 8.1 6.2 0.0 3.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA PF00004.29 PFH33296.1 - 4.7e-43 146.8 0.1 1.3e-42 145.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PFH33296.1 - 1.3e-12 47.3 0.1 2.6e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 PFH33296.1 - 9e-07 29.4 0.2 2.2e-05 24.9 0.2 3.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 PFH33296.1 - 4.8e-06 26.8 0.3 1.3e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PFH33296.1 - 5.6e-06 26.4 0.0 2e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 PFH33296.1 - 1.9e-05 24.5 0.5 5.6e-05 23.0 0.5 1.9 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 PFH33296.1 - 4.5e-05 23.2 0.0 8.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PFH33296.1 - 0.00028 21.1 3.7 0.009 16.3 0.6 2.7 2 1 0 2 2 1 1 AAA domain Filament PF00038.21 PFH33296.1 - 0.00033 20.3 0.2 0.00085 19.0 0.2 1.7 1 0 0 1 1 1 1 Intermediate filament protein DUF2072 PF09845.9 PFH33296.1 - 0.00055 20.2 1.5 0.0016 18.7 1.5 1.7 1 0 0 1 1 1 1 Zn-ribbon containing protein AAA_18 PF13238.6 PFH33296.1 - 0.0023 18.5 0.1 0.0094 16.5 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 PFH33296.1 - 0.0025 18.0 0.0 0.0057 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 PFH33296.1 - 0.0026 17.5 0.0 0.0063 16.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase PF06745.13 PFH33296.1 - 0.0035 16.7 0.1 0.076 12.3 0.0 2.5 2 0 0 2 2 2 1 KaiC TIP49 PF06068.13 PFH33296.1 - 0.0041 16.4 0.1 0.011 14.9 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_3 PF07726.11 PFH33296.1 - 0.0072 16.2 0.1 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 PFH33296.1 - 0.01 15.7 0.4 0.28 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PFH33296.1 - 0.011 16.0 0.6 0.027 14.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 PFH33296.1 - 0.013 14.2 1.8 0.24 10.0 0.8 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 PFH33296.1 - 0.014 14.8 0.1 0.028 13.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 PFH33296.1 - 0.022 14.5 0.0 0.058 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 PFH33296.1 - 0.024 14.1 0.1 0.16 11.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_17 PF13207.6 PFH33296.1 - 0.026 15.0 0.6 0.12 12.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 PFH33296.1 - 0.026 14.5 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 PFH33296.1 - 0.026 14.9 0.0 0.071 13.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Sigma54_activat PF00158.26 PFH33296.1 - 0.028 14.1 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 PFH33296.1 - 0.029 13.9 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region SlyX PF04102.12 PFH33296.1 - 0.041 14.5 3.7 0.17 12.6 3.7 2.0 1 0 0 1 1 1 0 SlyX Parvo_NS1 PF01057.17 PFH33296.1 - 0.047 12.8 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 PFH33296.1 - 0.051 14.1 0.5 0.3 11.6 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 PFH33296.1 - 0.051 13.1 0.2 0.18 11.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 PFH33296.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 PFH33296.1 - 0.12 12.3 0.0 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 PFH33296.1 - 0.24 11.9 2.9 21 5.5 3.1 2.4 2 0 0 2 2 2 0 AAA domain HAUS-augmin3 PF14932.6 PFH33296.1 - 0.27 10.8 2.3 0.52 9.8 2.3 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 V-SNARE PF05008.15 PFH33296.1 - 0.36 11.2 5.3 0.24 11.8 2.7 2.1 2 0 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus TolA_bind_tri PF16331.5 PFH33296.1 - 0.78 9.9 9.6 1.2 9.3 6.9 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation MutS_V PF00488.21 PFH33297.1 - 2.9e-78 262.2 0.9 7.1e-78 261.0 0.2 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 PFH33297.1 - 1.8e-17 64.2 0.3 1.8e-17 64.2 0.3 2.3 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.18 PFH33297.1 - 2.8e-08 34.0 0.3 5.5e-08 33.0 0.3 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 PFH33297.1 - 0.0017 18.7 0.2 0.006 16.9 0.0 2.0 2 0 0 2 2 2 1 MutS domain II AAA_27 PF13514.6 PFH33297.1 - 0.081 12.5 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 PFH33297.1 - 0.093 12.6 0.2 11 5.9 0.0 2.7 2 0 0 2 2 2 0 NTPase Calc_CGRP_IAPP PF00214.19 PFH33297.1 - 0.11 12.8 0.6 0.52 10.7 0.2 2.4 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family AAA_14 PF13173.6 PFH33297.1 - 0.14 12.2 0.0 1.2 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 PFH33297.1 - 0.48 10.9 0.0 0.48 10.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 PFH33297.1 - 0.7 10.1 3.9 0.75 10.0 0.6 2.7 2 1 0 2 2 2 0 AAA domain ABM PF03992.16 PFH33298.1 - 0.00053 20.0 0.0 0.00097 19.2 0.0 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase zf-CDGSH PF09360.10 PFH33299.1 - 1.1e-10 41.5 0.1 2.1e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type zf-Tim10_DDP PF02953.15 PFH33300.1 - 2.1e-14 52.9 0.3 2.6e-14 52.6 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 PFH33300.1 - 0.021 14.5 0.7 0.13 12.0 0.8 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) TIL PF01826.17 PFH33300.1 - 0.038 14.2 1.3 0.053 13.8 1.3 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain AMPK1_CBM PF16561.5 PFH33302.1 - 7.5e-11 42.1 0.0 1.4e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase PsbW PF07123.12 PFH33302.1 - 0.27 11.3 1.2 0.91 9.5 1.2 1.9 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) IQ PF00612.27 PFH33302.1 - 4.5 7.3 8.9 4 7.5 1.6 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif ISP1_C PF18161.1 PFH33304.1 - 2.4e-42 143.3 0.9 3e-42 143.0 0.9 1.1 1 0 0 1 1 1 1 ISP1 C-terminal ISP3_C PF18045.1 PFH33304.1 - 1.5e-41 140.7 1.7 2e-41 140.3 1.7 1.1 1 0 0 1 1 1 1 ISP3 C-terminal T_Ag_DNA_bind PF02217.16 PFH33304.1 - 0.056 14.0 0.2 0.95 10.1 0.0 2.2 1 1 1 2 2 2 0 Origin of replication binding protein GvpL_GvpF PF06386.11 PFH33304.1 - 0.15 12.0 0.5 0.62 9.9 0.0 1.8 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DNA_pol_phi PF04931.13 PFH33306.1 - 2.3 6.2 16.8 3.6 5.6 16.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi RAP PF08373.10 PFH33307.1 - 1.1e-14 54.3 0.1 2.3e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 PFH33307.1 - 1.8e-06 28.0 0.3 5.8e-06 26.4 0.3 1.8 1 0 0 1 1 1 1 REase_MTES_1575 DNA_primase_S PF01896.19 PFH33308.1 - 1e-49 169.0 0.0 1.7e-49 168.2 0.0 1.4 1 0 0 1 1 1 1 DNA primase small subunit EF-hand_1 PF00036.32 PFH33309.1 - 2.9e-29 98.4 12.7 9.3e-09 34.2 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PFH33309.1 - 6.4e-28 97.0 11.2 3.3e-14 53.1 3.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH33309.1 - 1.7e-25 86.7 9.8 4.3e-08 32.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PFH33309.1 - 7.8e-21 73.7 13.7 9.2e-14 51.0 1.1 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 PFH33309.1 - 4.8e-14 52.4 1.3 6.9e-07 29.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PFH33309.1 - 4.6e-08 32.2 10.5 0.0078 15.7 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 PFH33309.1 - 5.9e-05 23.0 4.9 0.1 12.5 0.1 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 PFH33309.1 - 8.8e-05 22.5 1.7 1.5 8.7 0.0 3.7 1 1 3 4 4 4 1 Caleosin related protein EF-hand_14 PF17959.1 PFH33309.1 - 0.00052 20.3 2.8 0.66 10.4 0.3 2.7 1 1 1 2 2 2 2 EF-hand domain SurA_N_2 PF13623.6 PFH33309.1 - 0.0035 17.2 0.9 1 9.2 0.1 2.5 2 1 0 2 2 2 2 SurA N-terminal domain FlgD PF03963.14 PFH33309.1 - 0.035 14.4 0.1 0.12 12.7 0.0 1.9 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region MgtE_N PF03448.17 PFH33309.1 - 0.039 14.6 0.8 0.039 14.6 0.8 2.2 2 1 0 2 2 2 0 MgtE intracellular N domain DUF1636 PF07845.11 PFH33309.1 - 0.051 14.0 0.0 0.2 12.1 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1636) Ribosomal_L23 PF00276.20 PFH33310.1 - 5.7e-12 45.8 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Glycos_transf_2 PF00535.26 PFH33311.1 - 2.8e-20 72.8 0.0 2.1e-10 40.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PFH33311.1 - 2.6e-06 27.5 0.0 0.037 13.9 0.0 3.1 3 0 0 3 3 3 2 Glycosyltransferase like family 2 APG9 PF04109.16 PFH33312.1 - 1.7e-91 307.6 7.1 1.6e-82 278.1 2.1 2.1 2 0 0 2 2 2 2 Autophagy protein Apg9 DUF5083 PF16890.5 PFH33312.1 - 0.063 13.0 0.4 0.13 11.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) DnaJ PF00226.31 PFH33313.1 - 2.6e-20 72.3 0.3 6.3e-20 71.1 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 PFH33313.1 - 3.9e-14 52.4 0.0 5.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain SelK_SelG PF10961.8 PFH33314.1 - 0.0027 18.3 1.5 1.1 9.9 0.1 2.1 1 1 1 2 2 2 2 Selenoprotein SelK_SelG WBS_methylT PF12589.8 PFH33315.1 - 1.3e-16 61.1 9.7 1.3e-16 61.1 9.7 1.8 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 PFH33315.1 - 5.8e-09 36.5 0.0 1.5e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH33315.1 - 2.5e-08 34.5 0.0 8.1e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 PFH33315.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 PFH33315.1 - 0.026 14.3 0.0 0.13 12.1 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 PFH33315.1 - 0.06 14.1 0.1 0.24 12.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 PFH33315.1 - 0.097 12.5 0.2 0.3 10.9 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain PUF PF00806.19 PFH33316.1 - 7.4e-49 160.8 0.2 4.4e-06 26.1 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Csm1_N PF18504.1 PFH33317.1 - 1.2 9.5 4.2 2.4 8.6 4.2 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain REPA_OB_2 PF16900.5 PFH33318.1 - 3.1e-20 71.9 0.5 9.2e-20 70.4 0.5 1.8 1 0 0 1 1 1 1 Replication protein A OB domain Rep_fac-A_C PF08646.10 PFH33318.1 - 4.9e-12 45.8 0.1 1.7e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.25 PFH33318.1 - 1.2e-08 34.9 0.3 1e-05 25.4 0.1 3.6 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain POT1PC PF16686.5 PFH33318.1 - 0.011 15.6 0.0 0.059 13.2 0.0 2.1 2 0 0 2 2 2 0 ssDNA-binding domain of telomere protection protein Sgf11 PF08209.11 PFH33318.1 - 0.14 11.7 1.3 12 5.5 0.1 2.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DZR PF12773.7 PFH33318.1 - 1.4 9.0 4.6 0.35 10.9 0.7 2.0 2 0 0 2 2 2 0 Double zinc ribbon Acetyltransf_1 PF00583.25 PFH33319.1 - 1.2e-06 28.7 0.0 3e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PFH33319.1 - 1.6e-05 25.3 0.0 3.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PFH33319.1 - 0.0029 17.5 0.0 0.0071 16.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PFH33319.1 - 0.023 14.6 0.0 0.068 13.1 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein IMCp PF12314.8 PFH33320.1 - 3.7e-18 65.6 97.5 3.4e-12 46.5 24.6 3.5 1 1 3 4 4 4 4 Inner membrane complex protein Sel1 PF08238.12 PFH33322.1 - 2.8e-36 123.1 38.6 4e-08 33.7 0.2 8.7 8 1 1 9 9 9 7 Sel1 repeat TPR_7 PF13176.6 PFH33322.1 - 0.025 14.6 14.4 6.9 7.0 0.2 6.2 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH33322.1 - 0.073 13.7 0.0 0.073 13.7 0.0 6.4 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 PFH33322.1 - 0.98 9.9 8.5 3.2 8.4 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat Dioxygenase_N PF04444.14 PFH33323.1 - 0.16 11.8 0.0 4.7 7.1 0.0 2.8 3 0 0 3 3 3 0 Catechol dioxygenase N terminus AAA_13 PF13166.6 PFH33323.1 - 0.4 9.3 0.2 0.55 8.8 0.2 1.1 1 0 0 1 1 1 0 AAA domain Peptidase_C65 PF10275.9 PFH33324.1 - 2.7e-50 171.1 0.0 1.4e-48 165.5 0.0 2.0 2 0 0 2 2 2 2 Peptidase C65 Otubain COPI_assoc PF08507.10 PFH33325.1 - 0.00069 19.7 6.3 0.0011 19.0 6.3 1.3 1 0 0 1 1 1 1 COPI associated protein LRR_4 PF12799.7 PFH33327.1 - 5e-52 173.0 32.3 4.2e-06 27.0 1.3 13.7 11 2 2 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH33327.1 - 8.2e-41 137.6 44.3 7.8e-10 38.4 0.7 12.7 10 2 5 15 15 15 12 Leucine rich repeat LRR_9 PF14580.6 PFH33327.1 - 1.3e-39 135.5 17.8 2.7e-12 46.5 0.1 9.6 4 4 5 10 10 10 9 Leucine-rich repeat LRR_6 PF13516.6 PFH33327.1 - 8.1e-08 31.7 35.7 0.97 9.7 0.1 15.8 18 0 0 18 18 18 2 Leucine Rich repeat LRR_1 PF00560.33 PFH33327.1 - 0.07 13.7 43.0 0.27 11.9 0.6 13.9 15 2 0 15 15 15 0 Leucine Rich Repeat C2 PF00168.30 PFH33328.1 - 9.2e-42 141.5 0.0 4.2e-10 39.8 0.0 6.7 6 0 0 6 6 6 6 C2 domain adh_short PF00106.25 PFH33329.1 - 1.6e-29 102.8 0.1 9.9e-22 77.4 0.1 3.2 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PFH33329.1 - 6e-12 45.6 0.0 3.7e-09 36.5 0.0 3.0 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PFH33329.1 - 0.00074 19.5 0.1 0.0013 18.7 0.1 1.3 1 0 0 1 1 1 1 KR domain DEAD PF00270.29 PFH33330.1 - 1e-26 93.8 0.0 2.8e-26 92.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH33330.1 - 9.3e-25 87.1 0.0 1.8e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 PFH33330.1 - 0.004 16.5 0.0 0.004 16.5 0.0 2.3 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit NPL PF17800.1 PFH33331.1 - 1.2e-15 57.9 0.1 1.2e-15 57.9 0.1 2.7 2 1 0 2 2 2 1 Nucleoplasmin-like domain Nop14 PF04147.12 PFH33331.1 - 0.064 11.5 42.4 0.1 10.8 42.4 1.3 1 0 0 1 1 1 0 Nop14-like family DHH PF01368.20 PFH33332.1 - 1.9e-07 31.2 0.0 4.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.14 PFH33332.1 - 2.8e-07 30.8 0.0 5.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain Ndc80_HEC PF03801.13 PFH33333.1 - 4e-22 78.5 0.0 1.1e-21 77.1 0.0 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family Spc7 PF08317.11 PFH33333.1 - 1.7e-05 23.9 18.4 1.7e-05 23.9 18.4 3.0 2 1 1 3 3 3 1 Spc7 kinetochore protein Pox_F11 PF04943.12 PFH33333.1 - 0.006 15.7 1.2 0.006 15.7 1.2 2.0 2 0 0 2 2 2 1 Poxvirus F11 protein Noc2 PF03715.13 PFH33333.1 - 0.13 11.5 0.1 0.13 11.5 0.1 2.4 2 0 0 2 2 2 0 Noc2p family Baculo_PEP_C PF04513.12 PFH33333.1 - 1.4 8.9 11.8 0.3 11.1 0.2 3.3 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RasGAP_C PF03836.15 PFH33333.1 - 2.4 8.3 25.0 1.9 8.6 2.4 4.0 4 0 0 4 4 4 0 RasGAP C-terminus FapA PF03961.13 PFH33333.1 - 5 5.6 20.2 0.76 8.3 7.7 2.8 2 1 0 2 2 2 0 Flagellar Assembly Protein A DUF16 PF01519.16 PFH33333.1 - 5.4 7.5 32.0 0.18 12.3 1.2 4.4 2 2 2 4 4 4 0 Protein of unknown function DUF16 Img2 PF05046.14 PFH33333.1 - 7.8 6.9 7.5 5.8 7.3 0.2 3.1 2 1 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) NPV_P10 PF05531.12 PFH33333.1 - 9.2 6.8 13.7 2.8 8.5 0.1 4.3 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Mcm10 PF09332.11 PFH33334.1 - 5.6e-18 65.5 7.1 5.6e-18 65.5 7.1 2.8 3 0 0 3 3 3 1 Mcm10 replication factor zf-primase PF09329.11 PFH33334.1 - 8e-07 28.8 0.1 8e-07 28.8 0.1 1.9 2 0 0 2 2 2 1 Primase zinc finger TraH PF06122.11 PFH33334.1 - 0.17 11.2 1.3 0.29 10.4 1.3 1.3 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein PH PF00169.29 PFH33338.1 - 1.8e-18 67.0 0.8 2.3e-18 66.6 0.8 1.1 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 PFH33338.1 - 6e-06 26.5 0.1 9.5e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 PFH33338.1 - 8.2e-06 26.2 1.5 0.00027 21.3 1.5 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 PFH33338.1 - 0.00043 20.4 0.2 0.0028 17.7 0.2 1.9 1 1 0 1 1 1 1 PH domain PH_13 PF16652.5 PFH33338.1 - 0.0059 16.4 0.0 0.0079 16.0 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain GTP1_OBG PF01018.22 PFH33339.1 - 9.8e-17 61.0 0.3 1.5e-16 60.3 0.3 1.3 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 PFH33339.1 - 4.7e-11 42.8 0.0 1.3e-10 41.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PFH33339.1 - 0.00096 18.7 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B zf-DNL PF05180.12 PFH33340.1 - 1.6e-29 101.6 0.1 2.7e-29 100.9 0.1 1.4 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 PFH33340.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 CSL zinc finger Myticin-prepro PF10690.9 PFH33340.1 - 0.14 12.4 0.8 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel Noc2 PF03715.13 PFH33342.1 - 5.1e-30 104.7 5.4 1.5e-29 103.2 2.5 2.6 2 1 0 2 2 2 1 Noc2p family Prothymosin PF03247.14 PFH33342.1 - 0.0068 16.9 17.4 0.0068 16.9 17.4 6.3 6 1 1 7 7 7 1 Prothymosin/parathymosin family ABC_membrane PF00664.23 PFH33343.1 - 2.2e-100 335.8 9.3 1.5e-51 175.7 1.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PFH33343.1 - 1.4e-67 226.5 0.1 3.1e-33 115.2 0.0 2.9 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PFH33343.1 - 2.4e-13 50.1 4.4 2.4e-06 27.1 0.1 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 PFH33343.1 - 4.7e-09 36.6 0.7 0.0023 18.2 0.0 3.6 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 PFH33343.1 - 1.4e-07 31.6 0.0 0.013 15.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 PFH33343.1 - 3.7e-07 30.7 6.8 0.0017 18.8 0.3 3.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 PFH33343.1 - 1.4e-06 28.1 2.4 1 8.9 0.0 4.1 4 0 0 4 4 4 3 AAA domain Zeta_toxin PF06414.12 PFH33343.1 - 6.4e-06 25.6 0.2 0.0042 16.4 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_29 PF13555.6 PFH33343.1 - 6.5e-06 25.8 0.4 0.18 11.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 PFH33343.1 - 7.1e-06 26.5 5.9 0.13 12.7 0.7 4.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 PFH33343.1 - 7.5e-06 26.0 0.2 0.056 13.4 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 PFH33343.1 - 1.2e-05 25.0 0.1 0.2 11.2 0.0 2.9 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_21 PF13304.6 PFH33343.1 - 1.2e-05 25.3 0.3 0.2 11.4 0.0 4.0 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PFH33343.1 - 2.6e-05 24.1 0.1 0.024 14.4 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 PFH33343.1 - 3e-05 24.0 0.7 0.36 10.8 0.0 3.7 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 PFH33343.1 - 0.00015 22.1 0.2 0.12 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 PFH33343.1 - 0.00065 18.6 3.4 0.22 10.3 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class G-alpha PF00503.20 PFH33343.1 - 0.00073 18.8 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit RNA_helicase PF00910.22 PFH33343.1 - 0.00083 19.7 0.1 2.6 8.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 PFH33343.1 - 0.0012 18.8 1.2 4.2 7.3 0.1 3.7 4 0 0 4 4 4 0 NACHT domain IstB_IS21 PF01695.17 PFH33343.1 - 0.0013 18.5 0.2 4 7.1 0.0 3.8 3 0 0 3 3 3 1 IstB-like ATP binding protein ATP-synt_ab PF00006.25 PFH33343.1 - 0.0013 18.4 4.8 0.98 9.0 2.9 3.2 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 PFH33343.1 - 0.0014 19.1 1.4 0.88 10.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 PFH33343.1 - 0.002 18.7 0.1 2.9 8.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PFH33343.1 - 0.0029 17.3 7.7 0.67 9.6 2.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.6 PFH33343.1 - 0.0029 17.6 0.3 8.9 6.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 PFH33343.1 - 0.003 18.1 2.3 2.9 8.4 0.1 3.0 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.6 PFH33343.1 - 0.003 17.8 4.4 0.17 12.1 0.4 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 PFH33343.1 - 0.0082 16.2 0.0 6.5 6.9 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase TniB PF05621.11 PFH33343.1 - 0.0093 15.4 0.0 13 5.1 0.0 3.7 4 0 0 4 4 4 0 Bacterial TniB protein PRK PF00485.18 PFH33343.1 - 0.0099 15.6 0.3 4.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 PFH33343.1 - 0.018 14.2 0.2 3.9 6.6 0.1 2.6 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 PFH33343.1 - 0.019 14.7 0.2 9.3 5.9 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 PFH33343.1 - 0.019 15.1 0.7 6.7 6.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 PFH33343.1 - 0.036 13.2 0.0 3.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 PFH33343.1 - 0.037 13.4 0.1 5.9 6.2 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI GMC_oxred_N PF00732.19 PFH33343.1 - 0.04 13.3 0.8 8.8 5.6 0.0 3.0 3 0 0 3 3 3 0 GMC oxidoreductase AAA_24 PF13479.6 PFH33343.1 - 0.049 13.4 0.1 8.7 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 PFH33343.1 - 0.062 13.0 0.2 4.1 7.2 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MoaE PF02391.17 PFH33343.1 - 0.081 13.2 0.7 8.3 6.7 0.1 2.9 2 0 0 2 2 2 0 MoaE protein TsaE PF02367.17 PFH33343.1 - 0.13 12.2 0.1 19 5.3 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE APS_kinase PF01583.20 PFH33343.1 - 0.16 11.8 0.2 12 5.7 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_19 PF13245.6 PFH33343.1 - 0.49 10.7 2.4 18 5.6 0.2 3.0 3 0 0 3 3 2 0 AAA domain ABC_membrane PF00664.23 PFH33344.1 - 1.8e-96 323.0 7.7 2.8e-48 164.9 1.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PFH33344.1 - 8.6e-67 223.9 0.0 2.5e-33 115.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PFH33344.1 - 9.4e-15 54.6 0.5 1.5e-06 27.9 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 PFH33344.1 - 7.7e-10 39.2 0.1 0.0014 18.9 0.0 3.9 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 PFH33344.1 - 7.8e-09 35.7 0.0 0.0034 17.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 PFH33344.1 - 4.2e-08 33.8 6.3 0.00058 20.3 0.2 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 PFH33344.1 - 8.2e-08 32.7 2.5 0.032 14.6 0.1 4.1 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 PFH33344.1 - 5.8e-07 29.6 0.0 0.058 13.2 0.0 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PFH33344.1 - 4.4e-06 26.3 0.4 0.05 13.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_5 PF07728.14 PFH33344.1 - 4.6e-06 26.7 0.3 0.11 12.5 0.0 3.8 5 0 0 5 5 4 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 PFH33344.1 - 5.6e-06 26.1 2.2 0.19 11.3 0.0 4.2 5 0 0 5 5 5 2 AAA domain Rad17 PF03215.15 PFH33344.1 - 3.4e-05 23.8 0.3 0.096 12.6 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_15 PF13175.6 PFH33344.1 - 3.7e-05 23.6 0.0 0.067 12.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 PFH33344.1 - 9.1e-05 21.4 4.3 0.047 12.5 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_7 PF12775.7 PFH33344.1 - 0.0002 20.9 0.2 0.79 9.2 0.1 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_30 PF13604.6 PFH33344.1 - 0.00024 20.9 1.8 1.4 8.6 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.6 PFH33344.1 - 0.00031 20.8 0.2 9.5 6.3 0.0 4.4 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 PFH33344.1 - 0.00035 21.1 1.6 1.1 9.8 0.1 3.2 3 0 0 3 3 3 2 AAA domain G-alpha PF00503.20 PFH33344.1 - 0.00039 19.7 0.0 0.069 12.3 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit NACHT PF05729.12 PFH33344.1 - 0.00041 20.3 0.4 0.4 10.6 0.0 3.1 3 0 0 3 3 3 1 NACHT domain RNA_helicase PF00910.22 PFH33344.1 - 0.00042 20.7 0.1 1.9 8.9 0.0 3.0 3 0 0 3 3 2 2 RNA helicase ATP-synt_ab PF00006.25 PFH33344.1 - 0.00044 20.0 3.5 0.28 10.8 0.0 3.3 3 1 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 PFH33344.1 - 0.00051 20.2 4.7 0.069 13.4 0.6 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 PFH33344.1 - 0.00083 18.7 0.2 0.37 10.1 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin Mg_chelatase PF01078.21 PFH33344.1 - 0.00085 18.8 0.0 0.31 10.4 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 PFH33344.1 - 0.00086 19.5 0.2 2.5 8.2 0.1 3.0 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 PFH33344.1 - 0.0012 19.1 0.3 0.85 9.9 0.2 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 PFH33344.1 - 0.0041 17.6 0.2 4.2 7.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 PFH33344.1 - 0.0062 16.6 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase PRK PF00485.18 PFH33344.1 - 0.008 15.9 0.1 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.13 PFH33344.1 - 0.011 14.9 0.0 2.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 PFH33344.1 - 0.013 15.2 0.1 0.84 9.4 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 PFH33344.1 - 0.017 14.3 0.1 2.8 7.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 PFH33344.1 - 0.03 14.0 0.1 11 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 PFH33344.1 - 0.042 13.6 1.1 7.2 6.3 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 PFH33344.1 - 0.056 13.9 0.2 19 5.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 PFH33344.1 - 0.058 13.1 4.3 14 5.4 0.0 4.4 5 0 0 5 5 5 0 IstB-like ATP binding protein TsaE PF02367.17 PFH33344.1 - 0.087 12.8 0.1 9.3 6.3 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 PFH33344.1 - 0.087 12.9 0.1 2.3 8.3 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain KAP_NTPase PF07693.14 PFH33344.1 - 0.12 11.6 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain tRNA_lig_kinase PF08303.11 PFH33344.1 - 0.18 11.9 0.4 32 4.6 0.0 2.7 3 0 0 3 3 2 0 tRNA ligase kinase domain MoaE PF02391.17 PFH33344.1 - 0.27 11.5 1.0 15 5.9 0.1 2.8 2 0 0 2 2 2 0 MoaE protein Zip PF02535.22 PFH33345.1 - 8.6e-30 104.1 8.1 8.7e-15 54.8 0.0 4.2 4 0 0 4 4 4 4 ZIP Zinc transporter Cnd1 PF12717.7 PFH33347.1 - 6.5e-06 26.3 0.7 0.0058 16.7 0.0 4.7 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 PFH33347.1 - 0.84 10.0 3.6 1.3 9.4 0.3 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Ribosomal_60s PF00428.19 PFH33348.1 - 7.1e-27 93.8 8.8 7.1e-27 93.8 8.8 1.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF4684 PF15736.5 PFH33348.1 - 0.11 11.1 3.5 0.13 10.9 3.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) Cyclin_N PF00134.23 PFH33349.1 - 1.6e-06 27.9 0.2 2.9e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2201_N PF13203.6 PFH33349.1 - 1.9 8.0 13.6 0.12 12.0 4.3 2.3 1 1 1 2 2 2 0 Putative metallopeptidase domain CAF1 PF04857.20 PFH33350.1 - 1.1e-24 87.2 1.0 4.5e-13 49.1 0.1 2.3 1 1 1 2 2 2 2 CAF1 family ribonuclease RAP PF08373.10 PFH33351.1 - 0.00049 20.1 0.0 0.00083 19.4 0.0 1.3 1 0 0 1 1 1 1 RAP domain Dynamin_M PF01031.20 PFH33353.1 - 3.1e-102 341.7 0.1 6.3e-102 340.6 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 PFH33353.1 - 2.4e-55 187.1 0.0 4e-55 186.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 PFH33353.1 - 1.1e-29 102.4 0.9 3.9e-29 100.6 0.8 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 PFH33353.1 - 9.3e-07 28.9 0.0 1.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 PFH33353.1 - 0.074 13.4 3.1 1.1 9.6 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_28 PF13521.6 PFH33353.1 - 0.14 12.4 0.1 0.5 10.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 PFH33353.1 - 0.18 11.3 0.0 5.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Ras PF00071.22 PFH33354.1 - 4.7e-58 195.4 0.1 5.6e-58 195.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH33354.1 - 9.4e-33 113.0 0.1 1.8e-32 112.1 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH33354.1 - 2.6e-15 56.3 0.0 3.9e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PFH33354.1 - 0.00067 19.7 0.0 0.0013 18.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PFH33354.1 - 0.0045 16.5 0.0 0.013 15.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PFH33354.1 - 0.0054 16.6 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 PFH33354.1 - 0.0071 15.7 0.0 0.0092 15.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 PFH33354.1 - 0.14 11.6 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ETF PF01012.21 PFH33356.1 - 4e-35 121.3 0.0 1.1e-34 119.9 0.0 1.6 1 1 0 1 1 1 1 Electron transfer flavoprotein domain TPR_19 PF14559.6 PFH33357.1 - 2.1e-07 31.3 0.7 4.8e-05 23.8 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PFH33357.1 - 1.1e-06 28.9 10.6 0.029 15.2 1.3 4.7 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 PFH33357.1 - 2.8e-06 27.0 5.8 0.002 18.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 PFH33357.1 - 0.00042 20.4 6.3 0.17 12.1 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TAF1_subA PF14929.6 PFH33357.1 - 0.0037 16.7 0.0 0.0074 15.8 0.0 1.4 1 1 0 1 1 1 1 TAF RNA Polymerase I subunit A TPR_1 PF00515.28 PFH33357.1 - 0.0073 16.1 1.9 0.21 11.5 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 PFH33357.1 - 0.01 16.4 0.4 4.8 8.0 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 PFH33357.1 - 0.012 16.2 5.7 0.15 12.8 1.5 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 PFH33357.1 - 0.025 15.0 0.1 4.7 7.8 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 PFH33357.1 - 0.062 13.6 4.4 0.71 10.2 1.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF601 PF04642.12 PFH33357.1 - 0.076 12.5 0.2 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 TPR_7 PF13176.6 PFH33357.1 - 0.12 12.5 5.2 5.2 7.3 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat FH2 PF02181.23 PFH33358.1 - 0.0037 16.5 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain UL41A PF17591.2 PFH33358.1 - 0.15 12.2 0.4 0.3 11.2 0.4 1.4 1 0 0 1 1 1 0 Herpesvirus UL41A YIEGIA PF14045.6 PFH33359.1 - 0.0074 15.2 0.9 0.012 14.4 0.9 1.2 1 0 0 1 1 1 1 YIEGIA protein Lyase_8_N PF08124.11 PFH33359.1 - 0.16 10.9 3.4 0.39 9.6 3.4 1.7 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain DUF99 PF01949.16 PFH33359.1 - 0.61 9.5 5.1 4.9 6.5 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function DUF99 Rad60-SLD_2 PF13881.6 PFH33360.1 - 7.3e-11 42.2 0.0 8.3e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 PFH33360.1 - 0.0033 17.1 0.0 0.021 14.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 PFH33360.1 - 0.045 14.3 0.0 0.049 14.2 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF1391 PF07151.12 PFH33360.1 - 0.075 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) Nrap_D2 PF17403.2 PFH33361.1 - 0.0012 18.7 0.1 0.0024 17.7 0.1 1.4 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain DEAD PF00270.29 PFH33363.1 - 3.5e-45 153.9 0.2 5.7e-45 153.2 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH33363.1 - 1.1e-29 103.0 0.0 1e-28 99.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH33363.1 - 1.3e-05 25.3 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PFH33363.1 - 6.6e-05 22.2 0.0 0.00012 21.3 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_RecD PF05127.14 PFH33363.1 - 0.013 15.3 0.8 0.055 13.3 0.0 2.4 3 0 0 3 3 3 0 Helicase DUF4082 PF13313.6 PFH33363.1 - 0.05 13.7 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) AAA_22 PF13401.6 PFH33363.1 - 0.6 10.4 4.1 0.86 9.9 0.8 2.8 2 1 0 2 2 2 0 AAA domain VMA21 PF09446.10 PFH33364.1 - 2.7e-08 33.8 3.1 3.9e-08 33.3 3.1 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF2975 PF11188.8 PFH33364.1 - 0.024 14.5 0.5 0.032 14.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Bac_export_3 PF01313.19 PFH33364.1 - 5.6 7.0 8.4 1.4 8.9 3.5 1.9 2 0 0 2 2 2 0 Bacterial export proteins, family 3 SLATT_1 PF18181.1 PFH33365.1 - 0.013 15.4 0.4 0.023 14.6 0.4 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 HHV-5_US34A PF17087.5 PFH33365.1 - 0.041 14.0 0.8 0.058 13.6 0.0 1.6 2 0 0 2 2 2 0 Herpesvirus US34A protein family WASH-7_C PF14746.6 PFH33365.1 - 0.073 12.8 0.4 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal ZZ PF00569.17 PFH33366.1 - 0.025 14.4 1.9 0.061 13.2 1.9 1.7 1 0 0 1 1 1 0 Zinc finger, ZZ type TMEM43 PF07787.12 PFH33366.1 - 1.3 8.3 5.1 3.5 6.9 5.1 1.8 1 1 0 1 1 1 0 Transmembrane protein 43 YcbB PF08664.10 PFH33366.1 - 6.4 6.8 12.0 3 7.9 6.3 2.3 2 0 0 2 2 2 0 YcbB domain SNARE_assoc PF09335.11 PFH33367.1 - 3.7e-16 59.7 1.6 3.7e-16 59.7 1.6 2.2 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF4191 PF13829.6 PFH33367.1 - 0.17 11.2 2.2 10 5.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Adenylsucc_synt PF00709.21 PFH33368.1 - 1.1e-161 538.5 0.0 1.2e-161 538.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase PA14 PF07691.12 PFH33369.1 - 1.7e-25 89.5 0.0 2.9e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 PA14 domain fn2 PF00040.19 PFH33369.1 - 0.0018 18.5 1.4 0.0018 18.5 1.4 2.0 2 0 0 2 2 2 1 Fibronectin type II domain DUF2939 PF11159.8 PFH33369.1 - 0.12 12.8 0.7 0.34 11.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) MAD PF05557.13 PFH33369.1 - 0.26 9.6 1.7 0.36 9.2 1.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein cwf18 PF08315.12 PFH33370.1 - 5.2e-24 85.4 1.8 7.4e-24 84.9 1.8 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor GREB1 PF15782.5 PFH33371.1 - 8.2 3.4 8.0 12 2.8 8.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glutaredoxin PF00462.24 PFH33372.1 - 7.5e-15 54.9 0.1 9.9e-15 54.5 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.6 PFH33372.1 - 3.9e-05 23.4 0.0 5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 PFH33372.1 - 0.00025 21.1 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 PFH33372.1 - 0.00074 19.9 0.0 0.00093 19.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 PFH33372.1 - 0.0066 16.9 0.9 0.014 15.8 0.9 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain NIF PF03031.18 PFH33372.1 - 0.013 15.3 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase DSBA PF01323.20 PFH33372.1 - 0.025 14.4 3.0 0.21 11.3 0.4 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain TraF PF13728.6 PFH33372.1 - 0.027 14.3 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 PFH33372.1 - 0.058 13.6 0.7 5.5 7.1 1.4 2.0 1 1 1 2 2 2 0 Thioredoxin GST_N_3 PF13417.6 PFH33372.1 - 0.15 12.5 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Peptidase_M24 PF00557.24 PFH33373.1 - 5.9e-19 68.6 0.2 8.4e-19 68.1 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF1749 PF08538.10 PFH33374.1 - 6.9e-55 186.2 0.0 8.5e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 PFH33374.1 - 2.2e-06 27.1 0.1 0.0022 17.3 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF900 PF05990.12 PFH33374.1 - 1.8e-05 24.4 0.2 3.6e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 PFH33374.1 - 3.8e-05 24.4 0.0 5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PFH33374.1 - 5.4e-05 23.0 0.0 0.069 12.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF915 PF06028.11 PFH33374.1 - 0.00011 21.7 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) VirJ PF06057.11 PFH33374.1 - 0.0012 18.8 0.0 0.018 15.0 0.0 2.4 2 1 0 2 2 2 1 Bacterial virulence protein (VirJ) FSH1 PF03959.13 PFH33374.1 - 0.009 15.7 0.0 0.032 13.9 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 PFH33374.1 - 0.01 15.4 0.0 0.029 13.9 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 PFH33374.1 - 0.02 14.5 0.2 4.6 6.7 0.1 2.4 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase LCAT PF02450.15 PFH33374.1 - 0.054 12.7 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Chlorophyllase2 PF12740.7 PFH33374.1 - 0.063 12.2 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme APG12 PF04110.13 PFH33375.1 - 6.7e-14 52.1 0.0 8.2e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Kazal_2 PF07648.15 PFH33377.1 - 2.2e-06 27.7 3.5 3.3e-06 27.1 3.5 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PFH33377.1 - 0.00088 19.2 4.0 0.0014 18.6 4.0 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Pkinase PF00069.25 PFH33378.1 - 9.4e-49 166.1 0.0 1.3e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33378.1 - 1.1e-15 57.6 0.0 1.9e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH33378.1 - 0.0075 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PFH33378.1 - 0.015 14.7 0.0 1.6 8.0 0.0 2.3 1 1 1 2 2 2 0 Kinase-like RIO1 PF01163.22 PFH33378.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Alpha-amyl_C2 PF07821.12 PFH33379.1 - 9.6e-16 57.8 0.2 2.2e-15 56.6 0.2 1.7 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain Alpha-amylase PF00128.24 PFH33379.1 - 4.5e-13 49.5 0.0 2.3e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain fn3 PF00041.21 PFH33379.1 - 0.0028 18.0 0.0 0.36 11.2 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III domain CENP-F_leu_zip PF10473.9 PFH33380.1 - 0.017 15.2 4.2 0.078 13.0 1.0 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_1 PF00515.28 PFH33381.1 - 9.6e-16 56.9 2.2 8e-05 22.3 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 PFH33381.1 - 2e-14 53.8 4.5 8.9e-05 22.9 0.2 4.4 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 PFH33381.1 - 1.6e-13 49.6 7.3 0.0017 18.3 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 PFH33381.1 - 6.7e-13 49.1 2.9 0.0068 17.0 0.1 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 PFH33381.1 - 1.5e-10 41.2 12.0 2.4e-05 24.5 0.3 5.2 6 0 0 6 6 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH33381.1 - 1.1e-09 38.3 9.8 0.036 14.3 0.1 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 PFH33381.1 - 1.5e-09 37.8 3.2 0.12 13.2 0.0 6.2 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 PFH33381.1 - 1.5e-08 34.2 4.0 0.21 11.9 0.1 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 PFH33381.1 - 3.4e-08 33.6 0.6 0.37 11.5 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PFH33381.1 - 5.5e-05 23.2 1.9 0.11 12.5 0.1 3.5 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.9 PFH33381.1 - 0.00021 20.2 0.4 0.00021 20.2 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_4 PF07721.14 PFH33381.1 - 0.0013 19.2 1.0 2.3 9.1 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 PFH33381.1 - 0.0051 16.8 7.3 0.013 15.5 0.0 4.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 PFH33381.1 - 0.016 15.0 0.1 0.45 10.5 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 PFH33381.1 - 0.05 13.6 1.2 5.2 7.1 0.0 3.3 3 1 0 3 3 3 0 Putative TPR-like repeat TPR_11 PF13414.6 PFH33381.1 - 0.056 13.1 0.1 0.98 9.2 0.0 2.8 3 0 0 3 3 3 0 TPR repeat SNAP PF14938.6 PFH33381.1 - 0.082 12.3 0.7 0.85 9.0 0.5 2.3 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP HIP1_clath_bdg PF16515.5 PFH33382.1 - 0.027 15.1 5.3 0.027 15.1 5.3 1.9 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Kinase-PPPase PF03618.14 PFH33382.1 - 0.088 12.6 1.5 0.14 11.9 1.5 1.2 1 0 0 1 1 1 0 Kinase/pyrophosphorylase Exonuc_VII_L PF02601.15 PFH33382.1 - 0.22 11.0 4.0 0.43 10.1 4.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 PFH33382.1 - 0.27 11.4 2.2 0.47 10.6 2.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 PFH33382.1 - 1 8.2 8.9 1.7 7.4 8.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Prenyltrans PF00432.21 PFH33383.1 - 0.089 12.6 1.9 0.5 10.2 0.9 2.7 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Ras PF00071.22 PFH33384.1 - 2.5e-43 147.5 0.5 3.5e-43 147.0 0.5 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH33384.1 - 1.1e-32 112.8 0.2 1.6e-32 112.3 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH33384.1 - 1.5e-10 40.8 0.2 2.2e-10 40.3 0.2 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PFH33384.1 - 5.8e-06 26.4 0.1 9.6e-06 25.7 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PFH33384.1 - 1.1e-05 25.4 1.2 0.047 13.6 0.1 2.8 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 PFH33384.1 - 2.1e-05 24.1 0.4 5.2e-05 22.9 0.3 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 PFH33384.1 - 0.0017 18.1 0.6 0.31 10.8 0.1 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 PFH33384.1 - 0.0032 17.0 0.6 1.4 8.5 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF3172 PF11371.8 PFH33384.1 - 0.02 14.6 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) Gtr1_RagA PF04670.12 PFH33384.1 - 0.039 13.3 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 PFH33384.1 - 0.057 13.8 0.1 0.18 12.2 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 PFH33384.1 - 0.1 12.7 0.1 0.24 11.4 0.1 1.7 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain HMA PF00403.26 PFH33385.1 - 0.0046 17.4 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain RNA_ligase PF09414.10 PFH33386.1 - 0.0072 16.7 0.0 7.4 6.9 0.0 2.8 3 0 0 3 3 3 2 RNA ligase DnaJ PF00226.31 PFH33387.1 - 1.7e-15 56.9 0.0 8.3e-09 35.4 0.0 2.3 2 0 0 2 2 2 2 DnaJ domain Flu_C_NS2 PF03555.14 PFH33388.1 - 1.7 8.9 5.0 0.97 9.7 1.0 2.1 1 1 1 2 2 2 0 Influenza C non-structural protein (NS2) NIF PF03031.18 PFH33389.1 - 1.6e-15 57.2 0.0 2.3e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PI3_PI4_kinase PF00454.27 PFH33390.1 - 4.8e-39 134.7 0.0 7.2e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 PFH33390.1 - 5.2e-08 32.6 1.2 2e-07 30.7 0.2 2.6 3 0 0 3 3 3 1 FATC domain TRAM_LAG1_CLN8 PF03798.16 PFH33391.1 - 6.2e-30 104.4 16.4 1.1e-29 103.6 16.4 1.4 1 0 0 1 1 1 1 TLC domain DUF4234 PF14018.6 PFH33391.1 - 0.037 14.1 4.2 2 8.6 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) PTPA PF03095.15 PFH33392.1 - 9.2e-103 343.8 0.0 1.4e-102 343.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein EMP70 PF02990.16 PFH33393.1 - 1.9e-140 469.0 1.8 1.9e-140 469.0 1.8 2.1 2 0 0 2 2 2 1 Endomembrane protein 70 partial_CstF PF15861.5 PFH33394.1 - 8.9e-21 73.5 0.0 1.6e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Partial cleavage stimulation factor domain RRM_1 PF00076.22 PFH33394.1 - 4.6e-16 58.4 0.0 9e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 PFH33394.1 - 1.7e-09 38.0 0.5 4.7e-09 36.6 0.5 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 SIR2 PF02146.17 PFH33395.1 - 6.5e-06 26.2 0.0 0.042 13.8 0.0 3.7 4 0 0 4 4 4 2 Sir2 family B9-C2 PF07162.11 PFH33396.1 - 2.4e-19 70.2 0.9 5.2e-16 59.3 0.1 2.2 1 1 1 2 2 2 2 Ciliary basal body-associated, B9 protein PGI PF00342.19 PFH33398.1 - 1.6e-194 647.1 0.0 1.9e-194 646.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.25 PFH33399.1 - 2e-30 106.1 0.0 9.3e-24 84.2 0.0 3.4 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33399.1 - 2.4e-14 53.3 0.0 3.5e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH33399.1 - 0.0017 17.7 0.1 0.0078 15.6 0.1 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 PFH33399.1 - 0.085 12.8 0.4 0.15 11.9 0.4 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HOASN PF14515.6 PFH33399.1 - 0.18 12.2 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices Raffinose_syn PF05691.12 PFH33400.1 - 1.2e-32 112.7 0.0 3.3e-15 55.0 0.0 3.2 3 1 0 3 3 3 2 Raffinose synthase or seed imbibition protein Sip1 GCV_T PF01571.21 PFH33401.1 - 1.2e-29 103.4 0.0 2.8e-22 79.3 0.0 3.1 2 1 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 PFH33401.1 - 6e-05 22.9 0.0 0.00019 21.3 0.0 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyrophosphatase PF00719.19 PFH33402.1 - 1.5e-42 145.1 0.0 1.9e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase GATA PF00320.27 PFH33403.1 - 8.1e-11 41.3 14.7 1.3e-05 24.7 3.3 2.9 2 0 0 2 2 2 2 GATA zinc finger Pro_isomerase PF00160.21 PFH33404.1 - 1.6e-44 152.0 0.8 4e-44 150.7 0.1 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.28 PFH33404.1 - 2.6e-31 107.8 0.0 5.5e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 PFH33404.1 - 1.6e-14 53.0 0.7 5.5e-05 22.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PFH33404.1 - 1.8e-13 49.4 1.8 2.1e-05 24.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 PFH33404.1 - 2.5e-10 39.9 0.1 0.0007 19.2 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 PFH33404.1 - 1.5e-08 34.2 0.2 0.0019 18.2 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PFH33404.1 - 9.6e-08 32.5 2.3 1.2e-06 29.0 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PFH33404.1 - 1.6e-05 25.3 2.2 0.031 15.1 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PFH33404.1 - 3e-05 24.4 1.5 0.047 14.2 0.5 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 PFH33404.1 - 3.3e-05 24.0 0.0 0.84 10.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PFH33404.1 - 0.0001 22.5 2.8 0.00044 20.5 0.3 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PFH33404.1 - 0.0011 18.8 1.3 0.0083 16.1 0.2 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 PFH33404.1 - 0.0038 17.3 0.3 0.046 13.9 0.2 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat DUF3856 PF12968.7 PFH33404.1 - 0.025 14.7 0.5 0.066 13.3 0.5 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 PFH33404.1 - 0.042 14.5 0.3 3.4 8.5 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH33404.1 - 0.063 13.5 0.2 0.16 12.2 0.0 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 BPS PF08947.10 PFH33404.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 BPS (Between PH and SH2) DUF4110 PF13422.6 PFH33404.1 - 0.24 11.5 4.5 0.28 11.3 1.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4110) MIT PF04212.18 PFH33404.1 - 1.4 9.0 4.1 3.1 8.0 0.3 2.9 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain End3 PF12761.7 PFH33404.1 - 1.7 8.8 4.5 1.7 8.8 0.4 2.1 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 LRR_8 PF13855.6 PFH33405.1 - 3.9e-11 42.5 3.4 0.00016 21.4 0.1 3.3 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PFH33405.1 - 1.3e-09 38.2 6.6 0.0078 16.6 0.1 4.4 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PFH33405.1 - 0.00067 19.2 1.4 0.0018 17.8 0.8 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 PFH33405.1 - 0.0035 17.3 4.8 16 5.9 0.2 5.4 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 PFH33405.1 - 0.31 11.7 7.7 1.1e+02 3.9 0.0 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat RRM_1 PF00076.22 PFH33406.1 - 2.2e-17 62.6 0.1 1.2e-16 60.2 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cupin_8 PF13621.6 PFH33408.1 - 1.3e-19 70.9 0.0 2.5e-19 70.0 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 PFH33408.1 - 3e-11 43.8 0.1 1.8e-10 41.3 0.1 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 PFH33408.1 - 0.0022 17.8 0.5 0.0062 16.4 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PFH33408.1 - 0.0057 16.5 0.1 0.019 14.8 0.1 1.9 1 0 0 1 1 1 1 F-box domain Cupin_2 PF07883.11 PFH33408.1 - 0.021 14.6 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Cupin domain Cupin_1 PF00190.22 PFH33408.1 - 0.042 13.5 0.1 0.071 12.7 0.1 1.3 1 0 0 1 1 1 0 Cupin Cupin_4 PF08007.12 PFH33408.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein AAA PF00004.29 PFH33409.1 - 4e-15 56.4 0.0 2.4e-13 50.7 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PFH33409.1 - 6.4e-12 46.2 2.6 8.5e-12 45.8 0.1 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 PFH33409.1 - 1e-07 32.3 0.0 1.2e-06 28.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 PFH33409.1 - 0.0019 18.3 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 PFH33409.1 - 0.0027 18.0 0.0 0.065 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 PFH33409.1 - 0.039 13.9 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 PFH33409.1 - 0.045 13.9 0.0 0.045 13.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 PFH33409.1 - 0.057 13.1 0.1 0.31 10.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 PFH33409.1 - 0.065 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 PFH33409.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 PFH33409.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region 5_3_exonuc_N PF02739.16 PFH33410.1 - 7.3e-30 104.0 0.0 2.9e-28 98.8 0.0 2.3 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 PFH33410.1 - 4.2e-11 43.3 0.0 7.6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.23 PFH33410.1 - 0.11 12.4 0.3 0.35 10.8 0.1 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif RBP_receptor PF14752.6 PFH33411.1 - 0.3 9.6 1.8 0.34 9.4 1.8 1.0 1 0 0 1 1 1 0 Retinol binding protein receptor RRM_1 PF00076.22 PFH33413.1 - 1.1e-17 63.6 0.0 1.8e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_NTP_bind PF07717.16 PFH33414.1 - 2.1e-15 56.8 0.0 5.3e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PFH33414.1 - 1.6e-13 50.9 0.1 1.6e-13 50.9 0.1 3.7 4 0 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PFH33414.1 - 4.5e-12 46.3 0.0 9.2e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PFH33414.1 - 1.6e-07 31.3 0.1 3e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PFH33414.1 - 0.00014 22.1 0.1 0.00088 19.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PFH33414.1 - 0.00091 19.0 0.0 0.00091 19.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 PFH33414.1 - 0.01 15.8 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DND1_DSRM PF14709.7 PFH33414.1 - 0.016 15.5 0.1 0.04 14.2 0.1 1.8 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_19 PF13245.6 PFH33414.1 - 0.028 14.8 0.0 0.086 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 PFH33414.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SET PF00856.28 PFH33415.1 - 2.5e-09 37.8 0.0 9.5e-07 29.3 0.0 2.4 1 1 0 1 1 1 1 SET domain DHHC PF01529.20 PFH33416.1 - 1.1e-30 106.5 9.9 1.6e-27 96.3 8.0 3.2 4 0 0 4 4 4 2 DHHC palmitoyltransferase ASFV_J13L PF05568.11 PFH33416.1 - 4.2 7.1 6.2 0.59 9.9 0.6 2.2 2 0 0 2 2 2 0 African swine fever virus J13L protein CPSase_L_D2 PF02786.17 PFH33418.1 - 1.6e-70 236.9 0.5 2.7e-70 236.1 0.5 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 PFH33418.1 - 1.9e-66 223.6 0.0 3.4e-66 222.8 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 PFH33418.1 - 6.7e-38 129.6 0.0 1.7e-37 128.3 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PFH33418.1 - 2.3e-34 117.7 0.0 9.8e-34 115.7 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 PFH33418.1 - 3.1e-29 102.4 0.0 6e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 PFH33418.1 - 1.6e-18 66.3 0.5 3.7e-18 65.1 0.5 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 PFH33418.1 - 4e-12 45.8 0.5 1.9e-05 24.4 0.3 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 PFH33418.1 - 3.1e-09 36.6 0.1 6.7e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 PFH33418.1 - 5.2e-07 29.4 0.0 1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 PFH33418.1 - 6e-06 26.9 0.4 0.04 14.6 0.2 2.8 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 PFH33418.1 - 0.0009 19.3 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 PFH33418.1 - 0.0052 16.0 0.1 0.67 9.1 0.0 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 PFH33418.1 - 0.047 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Peptidase_M23 PF01551.22 PFH33418.1 - 0.092 13.0 0.1 24 5.2 0.1 2.7 1 1 1 2 2 2 0 Peptidase family M23 RnfC_N PF13375.6 PFH33418.1 - 0.15 12.0 1.1 1.9 8.5 0.4 2.6 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain TPR_2 PF07719.17 PFH33419.1 - 0.0016 18.4 2.2 4.3 7.7 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PFH33419.1 - 3.2 8.1 10.5 1.1 9.6 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat GDPD PF03009.17 PFH33420.1 - 6.4e-27 94.9 0.0 9.5e-21 74.7 0.0 2.0 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 PFH33420.1 - 0.0035 16.9 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Glycos_transf_2 PF00535.26 PFH33421.1 - 3.2e-27 95.4 0.0 5.4e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PFH33421.1 - 0.0008 19.4 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RskA PF10099.9 PFH33421.1 - 0.02 15.2 0.3 0.029 14.7 0.3 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Pkinase PF00069.25 PFH33422.1 - 7.1e-48 163.3 0.0 9.7e-42 143.2 0.0 3.5 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33422.1 - 5.7e-20 71.7 0.0 2.7e-17 62.9 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 PFH33422.1 - 0.019 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase NAP PF00956.18 PFH33423.1 - 7.4e-59 199.1 0.0 7.4e-59 199.1 0.0 7.7 2 1 1 3 3 3 1 Nucleosome assembly protein (NAP) Cornifin PF02389.15 PFH33423.1 - 0.00061 20.0 81.9 0.82 9.9 21.3 4.8 1 1 4 5 5 5 5 Cornifin (SPRR) family SRP14 PF02290.15 PFH33424.1 - 1.7e-14 53.9 0.1 3.8e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle 14kD protein YrzO PF14142.6 PFH33424.1 - 0.016 15.1 0.0 0.042 13.7 0.0 1.7 2 0 0 2 2 2 0 YrzO-like protein LCCL PF03815.19 PFH33425.1 - 3.5e-18 65.5 0.3 5.8e-18 64.8 0.3 1.3 1 0 0 1 1 1 1 LCCL domain DEP PF00610.21 PFH33425.1 - 0.053 13.6 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PA14 PF07691.12 PFH33426.1 - 0.00049 19.9 0.0 0.00051 19.9 0.0 1.1 1 0 0 1 1 1 1 PA14 domain fn2 PF00040.19 PFH33427.1 - 1.4 9.3 4.9 1.4 9.2 0.1 2.4 2 1 0 2 2 2 0 Fibronectin type II domain p25-alpha PF05517.12 PFH33428.1 - 2e-10 41.1 0.1 3.7e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 p25-alpha DCX PF03607.17 PFH33428.1 - 5.8e-09 35.9 0.0 1.5e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Doublecortin GLE1 PF07817.13 PFH33428.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 GLE1-like protein CH_2 PF06294.11 PFH33429.1 - 3.5e-32 110.4 0.0 4.6e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 PFH33429.1 - 3.5e-13 49.2 0.0 5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 PFH33429.1 - 0.0019 18.4 0.0 0.0024 18.0 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Pox_polyA_pol_N PF12630.7 PFH33429.1 - 0.096 13.1 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain ACT_5 PF13710.6 PFH33429.1 - 0.21 11.5 0.9 0.33 10.8 0.2 1.7 2 0 0 2 2 2 0 ACT domain DUF1126 PF06565.12 PFH33430.1 - 4.4e-82 270.7 2.4 3.5e-31 107.1 0.1 3.9 4 0 0 4 4 4 3 DUF1126 PH-like domain EFP_N PF08207.12 PFH33430.1 - 0.0014 18.6 0.0 3.2 7.9 0.0 2.9 2 0 0 2 2 2 2 Elongation factor P (EF-P) KOW-like domain Sec34 PF04136.15 PFH33430.1 - 0.025 14.5 2.0 0.088 12.7 2.0 1.8 1 1 0 1 1 1 0 Sec34-like family ER_lumen_recept PF00810.18 PFH33432.1 - 3e-50 170.9 7.2 4.5e-50 170.3 7.2 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 PFH33432.1 - 0.0062 16.3 10.8 0.04 13.7 0.3 4.4 4 1 1 5 5 5 2 PQ loop repeat DUF1298 PF06974.13 PFH33433.1 - 7.5e-18 64.9 0.0 1.2e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 PFH33433.1 - 3.2e-06 27.1 7.6 0.00054 19.8 2.9 2.7 2 1 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain SET PF00856.28 PFH33434.1 - 7.5e-16 59.0 0.6 7.3e-15 55.8 0.0 2.7 2 1 0 2 2 2 1 SET domain SAD_SRA PF02182.17 PFH33434.1 - 2.4e-13 50.1 0.0 5.3e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 SAD/SRA domain Pre-SET PF05033.16 PFH33434.1 - 6.7e-09 36.4 4.0 9.6e-09 35.9 1.8 2.5 2 0 0 2 2 2 1 Pre-SET motif V-SNARE PF05008.15 PFH33434.1 - 0.085 13.2 1.3 1.6 9.2 0.1 2.9 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus BRCT_2 PF16589.5 PFH33436.1 - 1e-06 29.1 0.0 3e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain zf-CSL PF05207.13 PFH33437.1 - 2.1e-10 40.2 8.3 1.1e-09 37.8 8.3 2.1 1 1 0 1 1 1 1 CSL zinc finger zinc-ribbons_6 PF07191.12 PFH33437.1 - 0.053 13.5 0.6 0.11 12.5 0.6 1.5 1 0 0 1 1 1 0 zinc-ribbons Sld5 PF05916.11 PFH33439.1 - 6.4e-08 33.0 0.0 1e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein zf-CDGSH PF09360.10 PFH33440.1 - 5.7e-08 32.9 0.2 9.6e-08 32.1 0.2 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Bax1-I PF01027.20 PFH33441.1 - 1.2e-26 93.8 22.1 1.4e-26 93.6 22.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pyr_redox_2 PF07992.14 PFH33443.1 - 2.6e-34 118.8 0.0 2.3e-33 115.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PFH33443.1 - 5.4e-16 58.9 2.4 3.5e-15 56.3 0.2 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PFH33443.1 - 2.8e-09 36.7 0.1 1.3e-06 27.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PFH33443.1 - 6.1e-05 22.3 7.4 0.028 13.5 0.6 3.6 2 1 2 4 4 4 3 FAD binding domain HI0933_like PF03486.14 PFH33443.1 - 0.00051 18.9 0.9 0.33 9.6 0.1 3.3 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.24 PFH33443.1 - 0.00056 19.6 7.1 0.8 9.2 0.5 3.8 2 1 1 4 4 4 2 FAD dependent oxidoreductase NmrA PF05368.13 PFH33443.1 - 0.0021 17.7 0.8 0.005 16.4 0.7 1.6 2 0 0 2 2 2 1 NmrA-like family 3HCDH_N PF02737.18 PFH33443.1 - 0.0026 17.7 0.1 0.0068 16.3 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 PFH33443.1 - 0.0026 18.2 1.0 0.014 15.8 0.1 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.22 PFH33443.1 - 0.0031 16.6 0.2 0.0076 15.4 0.2 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 PFH33443.1 - 0.005 16.9 0.1 0.018 15.1 0.1 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 PFH33443.1 - 0.0062 16.7 0.3 0.057 13.7 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 PFH33443.1 - 0.0094 15.1 0.4 0.21 10.7 0.1 2.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 PFH33443.1 - 0.018 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) 2-Hacid_dh_C PF02826.19 PFH33443.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 PFH33443.1 - 0.027 14.1 0.1 0.043 13.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 PFH33443.1 - 0.04 14.2 0.1 0.15 12.3 0.1 2.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 PFH33443.1 - 0.043 13.5 0.0 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 PFH33443.1 - 0.064 12.5 0.1 0.16 11.3 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 PFH33443.1 - 0.085 12.3 0.2 0.19 11.1 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family FMO-like PF00743.19 PFH33443.1 - 0.094 11.1 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like TrkA_N PF02254.18 PFH33443.1 - 0.1 12.9 0.1 0.36 11.1 0.1 2.0 1 1 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 PFH33443.1 - 0.11 11.7 7.2 0.09 12.0 0.3 2.5 2 1 1 3 3 2 0 FAD binding domain Lycopene_cycl PF05834.12 PFH33443.1 - 0.12 11.4 0.5 0.81 8.7 0.1 2.1 1 1 1 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 PFH33443.1 - 0.14 12.2 0.0 0.41 10.6 0.0 1.9 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 PFH33443.1 - 0.55 10.2 9.9 9.8 6.1 0.1 4.0 4 1 1 5 5 4 0 FAD-NAD(P)-binding HEPN_Swt1 PF18731.1 PFH33444.1 - 0.00031 21.1 0.0 0.00073 19.9 0.0 1.6 1 0 0 1 1 1 1 Swt1-like HEPN WD40 PF00400.32 PFH33445.1 - 5.4e-09 36.5 6.0 0.0048 17.7 0.0 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH33445.1 - 3e-07 30.6 0.0 0.14 12.5 0.0 4.3 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 PFH33445.1 - 0.096 12.2 0.0 4.5 6.8 0.0 2.8 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region RPAP2_Rtr1 PF04181.13 PFH33446.1 - 4e-11 43.1 0.3 1.6e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 Rtr1/RPAP2 family tRNA_int_endo PF01974.17 PFH33448.1 - 7.3e-11 42.0 0.0 2.7e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 tRNA intron endonuclease, catalytic C-terminal domain PRIMA1 PF16101.5 PFH33449.1 - 0.045 13.8 1.2 0.11 12.6 1.2 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TIL PF01826.17 PFH33449.1 - 0.063 13.5 9.7 0.42 10.9 1.6 2.8 3 0 0 3 3 3 0 Trypsin Inhibitor like cysteine rich domain TMEM171 PF15471.6 PFH33449.1 - 4.4 6.2 5.0 3.5 6.5 2.8 1.8 1 1 0 2 2 2 0 Transmembrane protein family 171 Pkinase PF00069.25 PFH33450.1 - 2.7e-62 210.6 0.0 8.7e-61 205.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33450.1 - 4.2e-29 101.6 0.0 5.2e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PFH33450.1 - 8.1e-05 22.1 0.1 0.0002 20.8 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH33450.1 - 0.00042 20.3 0.3 0.0026 17.7 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 PFH33450.1 - 0.00092 18.9 0.4 0.0091 15.6 0.1 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PFH33450.1 - 0.0028 16.5 0.0 0.005 15.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PFH33450.1 - 0.0091 15.3 0.0 0.036 13.4 0.0 2.0 2 1 0 2 2 2 1 Kinase-like YgbB PF02542.16 PFH33453.1 - 5.3e-44 150.2 0.0 2.6e-43 148.0 0.0 1.9 1 1 0 1 1 1 1 YgbB family tRNA_edit PF04073.15 PFH33454.1 - 5.5e-07 29.7 0.3 1.2e-05 25.3 0.3 2.3 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF2373 PF10180.9 PFH33454.1 - 0.082 12.8 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DUF1160 PF06648.11 PFH33454.1 - 0.15 12.1 0.1 0.23 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) Methyltransf_23 PF13489.6 PFH33455.1 - 6e-17 62.0 0.0 8.5e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PFH33455.1 - 8.8e-16 57.9 0.0 3.6e-15 55.9 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 PFH33455.1 - 8.9e-16 58.3 0.0 1.5e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH33455.1 - 1e-14 55.0 0.0 1.7e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PFH33455.1 - 1.5e-10 41.1 0.0 2.6e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH33455.1 - 4.6e-10 40.1 0.0 7.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 PFH33455.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_9 PF08003.11 PFH33455.1 - 0.097 11.6 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DUF2194 PF09960.9 PFH33455.1 - 0.17 10.2 0.0 0.21 9.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) EF-hand_7 PF13499.6 PFH33456.1 - 1.9e-07 31.5 0.2 3.8e-07 30.5 0.2 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PFH33456.1 - 2.1e-07 30.0 0.2 0.024 14.2 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PFH33456.1 - 6.3e-07 28.8 0.3 0.011 15.6 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PFH33456.1 - 3.1e-05 23.2 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 PFH33456.1 - 0.00082 19.7 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 PFH33456.1 - 0.0053 16.6 0.8 0.99 9.3 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair TP2 PF01254.18 PFH33456.1 - 0.022 15.4 5.6 0.029 15.0 5.6 1.1 1 0 0 1 1 1 0 Nuclear transition protein 2 Cadherin_C_2 PF16492.5 PFH33456.1 - 0.059 14.1 0.1 0.11 13.3 0.1 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DHHC PF01529.20 PFH33457.1 - 2.1e-36 125.0 8.3 2.1e-36 125.0 8.3 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Tau95 PF09734.9 PFH33458.1 - 1.3e-24 87.6 0.2 8.5e-22 78.5 0.0 2.6 1 1 0 2 2 2 2 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 PFH33458.1 - 4.2e-10 39.9 1.0 2.2e-08 34.4 0.0 2.9 2 1 0 2 2 2 1 Tau95 Triple barrel domain B9-C2 PF07162.11 PFH33459.1 - 1.5e-41 142.4 0.0 2.3e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Ank_2 PF12796.7 PFH33460.1 - 1.9e-33 114.9 2.8 3.5e-12 46.8 0.0 3.8 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PFH33460.1 - 2.3e-26 91.8 3.0 2.2e-09 37.7 0.1 4.8 2 2 4 6 6 6 6 Ankyrin repeats (many copies) RNA_GG_bind PF10258.9 PFH33460.1 - 1.3e-20 73.3 0.4 2.8e-20 72.2 0.4 1.6 1 0 0 1 1 1 1 PHAX RNA-binding domain Ank_3 PF13606.6 PFH33460.1 - 7.1e-19 65.9 3.5 0.0099 16.3 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 PFH33460.1 - 7.5e-18 64.1 5.2 0.023 15.2 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 PFH33460.1 - 1.8e-10 40.8 4.0 3.6e-05 24.0 0.2 5.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) TPR_19 PF14559.6 PFH33461.1 - 2e-12 47.4 14.4 0.00098 19.6 0.0 7.4 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 PFH33461.1 - 1.6e-06 28.6 9.7 0.092 13.4 1.4 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH33461.1 - 6.4e-06 26.3 29.0 0.00012 22.2 0.3 6.6 5 1 2 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 HrpB1_HrpK PF09613.10 PFH33461.1 - 1.9e-05 24.3 5.2 0.097 12.3 0.1 3.6 4 0 0 4 4 4 3 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 PFH33461.1 - 0.0015 18.9 7.7 22 6.0 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 PFH33461.1 - 0.0021 18.2 0.5 2.7 8.2 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 PFH33461.1 - 0.0026 18.3 15.3 0.38 11.5 0.2 6.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 PFH33461.1 - 0.0098 16.6 16.9 0.06 14.2 0.2 6.6 6 2 2 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 PFH33461.1 - 0.017 15.3 11.6 10 6.6 0.2 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 PFH33461.1 - 0.047 13.8 1.1 0.047 13.8 1.1 8.7 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_12 PF13424.6 PFH33461.1 - 0.056 13.7 21.6 3.7 7.9 0.1 8.1 7 2 1 8 8 8 0 Tetratricopeptide repeat PPR PF01535.20 PFH33461.1 - 0.19 12.0 1.7 59 4.2 0.1 4.8 5 0 0 5 5 5 0 PPR repeat TPR_7 PF13176.6 PFH33461.1 - 0.81 9.9 12.7 19 5.6 0.0 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PFH33461.1 - 0.93 9.6 6.1 0.4 10.8 1.1 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 PFH33461.1 - 1.1 9.2 21.8 0.053 13.4 0.8 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Thioredoxin PF00085.20 PFH33463.1 - 3.4e-17 62.3 0.0 6.2e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 PFH33463.1 - 0.0015 18.5 0.0 0.45 10.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 PFH33463.1 - 0.0016 18.9 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 PFH33463.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 F plasmid transfer operon protein OST3_OST6 PF04756.13 PFH33463.1 - 0.024 14.0 0.6 0.034 13.5 0.0 1.5 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PFH33463.1 - 0.031 14.6 0.1 0.097 13.0 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.21 PFH33463.1 - 0.033 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.6 PFH33463.1 - 0.096 12.9 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 PFH33463.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin MMR_HSR1 PF01926.23 PFH33464.1 - 1e-15 57.8 0.0 2.9e-15 56.3 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP-bdg_M PF16360.5 PFH33464.1 - 0.0014 19.1 4.7 0.0018 18.8 0.4 2.9 2 0 0 2 2 2 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 PFH33464.1 - 0.025 15.3 0.2 0.31 11.7 0.1 2.5 2 0 0 2 2 2 0 GTP-binding GTPase N-terminal AAA_16 PF13191.6 PFH33464.1 - 0.037 14.4 2.5 0.78 10.1 0.1 3.4 3 1 0 3 3 3 0 AAA ATPase domain RsgA_GTPase PF03193.16 PFH33464.1 - 0.21 11.5 0.0 4.1 7.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 PFH33464.1 - 0.24 10.9 0.0 0.46 10.0 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B cEGF PF12662.7 PFH33465.1 - 9.3e-12 44.7 369.6 0.0014 18.5 2.6 40.9 41 1 1 42 42 42 26 Complement Clr-like EGF-like hEGF PF12661.7 PFH33465.1 - 7.6e-10 39.1 380.1 0.038 14.6 1.7 44.9 44 2 0 44 44 44 25 Human growth factor-like EGF FXa_inhibition PF14670.6 PFH33465.1 - 2.1e-07 31.1 489.7 0.085 13.1 2.8 40.9 29 11 12 41 41 41 25 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 PFH33465.1 - 9.7e-07 28.9 405.9 0.0021 18.2 5.7 40.4 41 0 0 41 41 41 18 EGF domain N_methyl PF07963.12 PFH33465.1 - 0.097 12.3 0.0 21 4.9 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic N-terminal methylation motif EGF PF00008.27 PFH33465.1 - 2.7 8.4 480.4 0.1 12.9 0.9 43.7 41 3 0 41 41 41 0 EGF-like domain Striatin PF08232.12 PFH33466.1 - 0.016 15.8 0.7 0.016 15.8 0.7 2.9 2 1 1 3 3 3 0 Striatin family Rad9 PF04139.13 PFH33467.1 - 1.9e-12 47.2 0.0 2e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 Rad9 PCNA_N PF00705.18 PFH33467.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain AIM3 PF17096.5 PFH33468.1 - 0.024 15.5 2.9 0.078 13.9 2.9 1.8 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Actin PF00022.19 PFH33469.1 - 3.4e-57 193.9 0.0 8.2e-35 120.2 0.0 2.9 2 1 0 2 2 2 2 Actin ER_lumen_recept PF00810.18 PFH33471.1 - 2.2e-05 25.3 13.5 4.2e-05 24.4 0.1 3.4 2 1 0 3 3 3 2 ER lumen protein retaining receptor FSAP_sig_propep PF03032.15 PFH33471.1 - 0.019 15.0 1.4 0.04 13.9 0.1 2.1 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide FAM176 PF14851.6 PFH33471.1 - 1.6 8.4 5.5 4.8 6.8 0.4 3.0 2 1 1 3 3 3 0 FAM176 family EF-hand_6 PF13405.6 PFH33472.1 - 0.00068 19.4 0.1 0.0049 16.7 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 PFH33472.1 - 0.0038 16.7 0.2 0.18 11.4 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 PFH33472.1 - 0.0072 16.8 0.3 0.12 12.9 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain pair Med26 PF08711.11 PFH33473.1 - 0.078 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain PIH1 PF08190.12 PFH33475.1 - 2.2e-05 24.0 0.1 0.021 14.3 0.0 3.1 3 0 0 3 3 3 2 PIH1 N-terminal domain PIH1_CS PF18201.1 PFH33475.1 - 0.00082 19.7 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain Pol_alpha_B_N PF08418.10 PFH33475.1 - 0.097 12.6 1.8 0.23 11.4 1.8 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal THF_DHG_CYH_C PF02882.19 PFH33476.1 - 3.3e-30 104.5 0.5 1.6e-29 102.3 0.4 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 PFH33476.1 - 1.6e-07 31.6 0.0 1.1e-06 28.9 0.0 2.3 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF3611 PF12263.8 PFH33476.1 - 0.19 11.6 1.6 0.36 10.7 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) SET PF00856.28 PFH33478.1 - 1.1e-09 38.9 1.9 0.066 13.6 0.0 3.7 2 1 1 3 3 3 3 SET domain KAR9 PF08580.10 PFH33481.1 - 0.48 8.9 2.4 0.69 8.4 2.4 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF3040 PF11239.8 PFH33481.1 - 1.3 9.4 4.8 2.4 8.5 0.6 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) FUSC PF04632.12 PFH33481.1 - 7.5 5.0 11.7 0.076 11.5 4.0 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family WD40 PF00400.32 PFH33482.1 - 6e-12 45.9 6.4 0.039 14.8 0.0 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH33482.1 - 0.0032 17.7 0.0 2 8.7 0.0 4.1 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 PFH33482.1 - 0.15 10.6 0.0 15 4.0 0.0 2.3 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin MAAL_C PF07476.11 PFH33483.1 - 0.054 12.6 1.1 0.1 11.8 0.3 1.8 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus PCYCGC PF13798.6 PFH33483.1 - 3 7.7 6.1 0.37 10.6 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif RE_TdeIII PF09520.10 PFH33483.1 - 4.4 6.9 13.8 0.013 15.2 1.6 2.3 2 1 0 2 2 2 0 Type II restriction endonuclease, TdeIII HHH PF00633.23 PFH33484.1 - 0.1 12.5 0.1 0.82 9.7 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 PFH33484.1 - 0.16 12.6 0.1 0.84 10.3 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain MFS_1 PF07690.16 PFH33485.1 - 4.6e-13 48.8 32.6 7.5e-13 48.1 32.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Synaptobrevin PF00957.21 PFH33486.1 - 1.3e-23 82.6 1.7 2e-23 82.0 1.7 1.3 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 PFH33486.1 - 0.024 14.7 0.2 0.032 14.3 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter IL12 PF03039.14 PFH33486.1 - 0.051 12.9 0.4 0.083 12.2 0.4 1.2 1 0 0 1 1 1 0 Interleukin-12 alpha subunit LMBR1 PF04791.16 PFH33486.1 - 0.091 11.6 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Sec20 PF03908.13 PFH33486.1 - 0.26 11.2 6.3 1.9 8.5 6.3 2.2 1 1 0 1 1 1 0 Sec20 CDP-OH_P_transf PF01066.21 PFH33487.1 - 3.4e-18 66.2 0.1 3.4e-18 66.2 0.1 3.7 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Hydrolase_4 PF12146.8 PFH33488.1 - 2.1e-23 82.9 0.4 2.5e-10 40.1 0.1 3.2 3 0 0 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PFH33488.1 - 0.058 13.0 0.6 1 8.9 0.2 2.9 3 1 0 3 3 3 0 alpha/beta hydrolase fold RAP1 PF07218.11 PFH33488.1 - 3.1 6.0 7.1 6.4 4.9 7.1 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Prefoldin PF02996.17 PFH33489.1 - 7e-20 71.1 2.4 1e-19 70.6 2.4 1.3 1 0 0 1 1 1 1 Prefoldin subunit SlyX PF04102.12 PFH33489.1 - 0.23 12.1 2.2 0.2 12.3 0.7 1.7 2 0 0 2 2 2 0 SlyX BRE1 PF08647.11 PFH33489.1 - 1.1 9.4 8.0 3.2 7.9 0.1 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Aldedh PF00171.22 PFH33490.1 - 6.5e-147 489.8 2.4 1.7e-111 373.0 0.9 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family PsaD PF02531.16 PFH33490.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 PsaD Myosin_head PF00063.21 PFH33491.1 - 2.4e-118 396.2 0.0 4.4e-67 226.8 0.0 5.1 4 2 0 4 4 4 4 Myosin head (motor domain) AAA_22 PF13401.6 PFH33491.1 - 0.056 13.7 0.2 0.2 12.0 0.2 1.9 1 0 0 1 1 1 0 AAA domain SCO1-SenC PF02630.14 PFH33493.1 - 3.3e-44 150.1 0.0 4.8e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 PFH33493.1 - 0.00095 19.1 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 PFH33493.1 - 0.0018 18.6 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like MEA1 PF06910.11 PFH33494.1 - 0.95 10.1 5.5 0.44 11.2 0.1 2.6 2 0 0 2 2 2 0 Male enhanced antigen 1 (MEA1) MMR_HSR1 PF01926.23 PFH33496.1 - 3.9e-17 62.4 0.0 7.4e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PFH33496.1 - 3.2e-06 27.1 0.2 0.046 13.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 PFH33496.1 - 0.00037 20.1 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B HTH_33 PF13592.6 PFH33496.1 - 0.0034 17.0 0.1 0.011 15.4 0.1 1.9 1 0 0 1 1 1 1 Winged helix-turn helix Dynamin_N PF00350.23 PFH33496.1 - 0.013 15.6 0.0 0.14 12.2 0.1 2.3 1 1 1 2 2 2 0 Dynamin family GTP_EFTU PF00009.27 PFH33496.1 - 0.031 13.8 0.0 0.081 12.5 0.0 1.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MnmE_helical PF12631.7 PFH33496.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 MnmE helical domain Inhibitor_I42 PF09394.10 PFH33497.1 - 0.011 16.2 0.0 0.028 14.8 0.0 1.8 1 1 1 2 2 2 0 Chagasin family peptidase inhibitor I42 Inhibitor_I71 PF12628.7 PFH33497.1 - 0.015 15.1 0.1 0.038 13.8 0.0 1.5 1 1 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor DUF4992 PF16383.5 PFH33497.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function MIF4G PF02854.19 PFH33500.1 - 5e-28 98.2 0.1 6.7e-28 97.8 0.1 1.2 1 0 0 1 1 1 1 MIF4G domain CNOT1_CAF1_bind PF16415.5 PFH33500.1 - 0.19 11.1 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain OCC1 PF15506.6 PFH33501.1 - 0.71 10.0 3.1 6.4 7.0 0.0 2.5 2 0 0 2 2 2 0 OCC1 family Phlebovirus_NSM PF07246.11 PFH33501.1 - 0.97 8.7 7.9 1.3 8.3 7.9 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Ras PF00071.22 PFH33502.1 - 3.8e-57 192.4 0.0 4.4e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH33502.1 - 5.7e-32 110.4 0.0 7.7e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH33502.1 - 1.3e-14 54.0 0.0 1.7e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PFH33502.1 - 1.2e-05 25.0 0.0 0.0014 18.2 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PFH33502.1 - 0.00013 22.0 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 PFH33502.1 - 0.0023 17.7 0.0 0.3 10.9 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 PFH33502.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MeaB PF03308.16 PFH33502.1 - 0.017 14.2 0.1 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 PFH33502.1 - 0.018 15.0 0.0 2.2 8.2 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase DAP3 PF10236.9 PFH33502.1 - 0.031 13.4 0.0 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 PFH33502.1 - 0.044 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 PFH33502.1 - 0.06 13.6 0.0 0.23 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 PFH33502.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit CS PF04969.16 PFH33504.1 - 4.8e-07 30.7 0.0 9.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 CS domain CDC37_N PF03234.14 PFH33504.1 - 0.00015 22.7 0.1 0.00015 22.7 0.1 2.1 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding Nop25 PF09805.9 PFH33505.1 - 1.2 9.6 11.9 2.1 8.8 11.9 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) PTS_2-RNA PF01885.16 PFH33507.1 - 3.8e-65 219.3 0.0 5.5e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family AAA_23 PF13476.6 PFH33508.1 - 1.1e-21 78.3 12.5 1.1e-21 78.3 12.5 7.3 3 2 0 3 3 3 1 AAA domain SMC_N PF02463.19 PFH33508.1 - 8.1e-13 48.3 1.2 3.6e-05 23.3 0.0 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 PFH33508.1 - 1.3e-08 35.0 7.2 0.0024 17.6 0.0 4.4 4 0 0 4 4 4 2 AAA ATPase domain AAA_21 PF13304.6 PFH33508.1 - 6.1e-07 29.5 0.0 0.019 14.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 PFH33508.1 - 0.00064 19.9 0.0 0.0028 17.8 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF4200 PF13863.6 PFH33508.1 - 0.011 16.2 15.2 0.011 16.2 15.2 11.0 6 4 3 9 9 9 0 Domain of unknown function (DUF4200) ABC_tran PF00005.27 PFH33508.1 - 0.014 15.9 0.1 0.014 15.9 0.1 6.0 6 3 0 6 6 6 0 ABC transporter AAA_29 PF13555.6 PFH33508.1 - 0.042 13.6 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 PFH33508.1 - 0.71 10.2 0.0 0.71 10.2 0.0 4.4 4 0 0 4 4 4 0 AAA domain NOT2_3_5 PF04153.18 PFH33512.1 - 8.3e-16 58.3 0.0 8.3e-16 58.3 0.0 3.0 3 1 0 3 3 3 1 NOT2 / NOT3 / NOT5 family DUF572 PF04502.13 PFH33512.1 - 0.0049 16.5 5.0 0.0077 15.9 5.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF572) GREB1 PF15782.5 PFH33512.1 - 0.71 6.9 14.0 0.9 6.6 14.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DAP_B PF07930.12 PFH33512.1 - 0.85 9.6 4.4 1.4 8.9 4.4 1.2 1 0 0 1 1 1 0 D-aminopeptidase, domain B zf-CCCH PF00642.24 PFH33513.1 - 1.4e-08 34.4 14.9 0.0035 17.2 2.5 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 PFH33513.1 - 0.0011 19.4 13.1 1.4 9.5 1.6 3.6 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 PFH33513.1 - 0.014 15.5 15.7 0.1 12.7 0.5 3.7 4 0 0 4 4 4 0 Zinc finger domain zf-CCCH_3 PF15663.5 PFH33513.1 - 0.1 12.9 3.6 0.5 10.6 3.6 2.1 1 1 0 1 1 1 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 PFH33513.1 - 0.46 10.3 11.2 0.14 12.0 2.0 3.4 3 0 0 3 3 3 0 CCCH-type zinc finger Sugar_tr PF00083.24 PFH33514.1 - 1.1e-67 228.9 24.8 1.3e-67 228.6 24.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PFH33514.1 - 2.7e-16 59.5 36.3 2.7e-16 59.5 36.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RanBP PF00641.18 PFH33515.1 - 2.3e-05 23.6 0.3 5.2e-05 22.5 0.3 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 PFH33515.1 - 0.023 14.1 0.2 0.062 12.7 0.2 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Peptidase_M76 PF09768.9 PFH33516.1 - 1e-22 80.7 0.0 3.7e-21 75.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase M76 family NAC PF01849.18 PFH33518.1 - 2.8e-19 68.8 0.0 5.2e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 NAC domain COQ9 PF08511.11 PFH33518.1 - 0.21 11.4 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 COQ9 PDEase_I PF00233.19 PFH33519.1 - 5.1e-64 216.3 0.1 7.9e-64 215.6 0.1 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase ArfGap PF01412.18 PFH33520.1 - 0.0074 16.3 0.4 0.013 15.6 0.4 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SUI1 PF01253.22 PFH33521.1 - 9.8e-22 77.3 0.2 1.8e-21 76.5 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Usp PF00582.26 PFH33521.1 - 7.4 7.1 8.7 7.3 7.1 0.1 2.7 3 0 0 3 3 3 0 Universal stress protein family CSD PF00313.22 PFH33522.1 - 3.4e-25 87.7 0.3 4.9e-25 87.2 0.3 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 PFH33522.1 - 0.001 18.7 0.1 0.0023 17.6 0.1 1.8 1 1 0 1 1 1 1 Ribonuclease B OB domain Pantoate_transf PF02548.15 PFH33523.1 - 1.2e-79 267.4 1.1 1.6e-79 266.9 1.1 1.2 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.11 PFH33523.1 - 4.4e-38 130.3 0.2 1.1e-37 129.1 0.2 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 PFH33523.1 - 5.5e-15 55.3 0.0 7e-14 51.7 0.0 2.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PEP_mutase PF13714.6 PFH33523.1 - 0.16 11.4 1.3 0.38 10.2 0.2 2.2 2 1 0 2 2 2 0 Phosphoenolpyruvate phosphomutase TB2_DP1_HVA22 PF03134.19 PFH33524.1 - 6.2e-28 96.5 6.8 9.3e-28 96.0 6.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2228 PF10228.9 PFH33525.1 - 4.2e-38 131.5 0.0 9.9e-27 94.3 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2228) DUF974 PF06159.13 PFH33526.1 - 1e-36 127.0 0.0 1.4e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Peptidase_M16 PF00675.20 PFH33527.1 - 6.7e-44 149.5 1.5 7.8e-42 142.8 0.1 2.8 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 PFH33527.1 - 9.1e-29 100.6 0.0 1.7e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 PFH33527.1 - 2.3e-28 99.5 0.1 1.6e-16 60.9 0.0 4.0 4 1 1 5 5 5 2 Peptidase M16 inactive domain CNTF PF01110.17 PFH33527.1 - 0.0049 16.3 0.5 0.015 14.7 0.0 2.0 3 0 0 3 3 3 1 Ciliary neurotrophic factor PriCT_1 PF08708.11 PFH33527.1 - 0.091 12.5 0.5 0.38 10.5 0.5 2.1 1 1 0 1 1 1 0 Primase C terminal 1 (PriCT-1) Na_sulph_symp PF00939.19 PFH33528.1 - 1.3e-47 163.0 0.0 9.1e-47 160.2 0.0 2.0 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 PFH33528.1 - 1.5e-33 116.3 34.5 1.1e-16 61.0 0.0 3.6 2 2 2 4 4 4 3 Citrate transporter Kinase-like PF14531.6 PFH33529.1 - 4.8e-32 111.4 0.0 6.5e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH33529.1 - 2e-06 27.4 0.0 6.9e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain IQ PF00612.27 PFH33529.1 - 5.1 7.2 6.2 11 6.2 2.1 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif HGTP_anticodon PF03129.20 PFH33530.1 - 6.2e-23 80.8 0.3 5.3e-22 77.8 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 PFH33530.1 - 3.2e-10 40.3 0.0 7.8e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 PFH33530.1 - 4.8e-06 26.6 1.6 1.7e-05 24.9 1.6 2.0 1 0 0 1 1 1 1 WHEP-TRS domain Plectin PF00681.20 PFH33530.1 - 0.14 12.1 0.0 20 5.2 0.0 3.1 2 0 0 2 2 2 0 Plectin repeat Acyltransferase PF01553.21 PFH33531.1 - 1.1e-09 38.0 0.1 2.3e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase RseC_MucC PF04246.12 PFH33531.1 - 0.66 9.9 3.1 1.7 8.6 3.1 1.7 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC ATP-synt_ab PF00006.25 PFH33532.1 - 3.2e-105 350.5 0.0 4.3e-105 350.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 PFH33532.1 - 4.7e-45 152.4 0.0 1e-44 151.3 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 PFH33532.1 - 5.5e-16 58.9 0.3 1.4e-15 57.6 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain PIP5K PF01504.18 PFH33533.1 - 8.6e-25 87.5 0.0 2.7e-11 43.2 0.0 3.5 2 1 1 3 3 3 3 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.21 PFH33533.1 - 3.9e-11 42.9 10.9 3.9e-11 42.9 10.9 3.5 2 0 0 2 2 2 1 FYVE zinc finger Cpn60_TCP1 PF00118.24 PFH33533.1 - 9.3e-07 27.8 0.0 3.2e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family BRO1 PF03097.18 PFH33534.1 - 3.9e-41 141.2 0.0 1.4e-40 139.3 0.0 1.9 1 1 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 PFH33534.1 - 3.3e-07 29.9 20.3 2.1e-05 24.0 20.3 3.1 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV DEAD PF00270.29 PFH33536.1 - 2.1e-27 96.0 0.0 3.6e-19 69.2 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH33536.1 - 3.1e-17 62.9 0.1 5.2e-17 62.2 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.25 PFH33537.1 - 2.8e-27 95.8 0.0 2.7e-12 46.6 0.0 3.5 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33537.1 - 3e-13 49.6 0.0 2.8e-06 26.8 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 PFH33537.1 - 4.2e-05 23.6 2.1 0.0001 22.3 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PFH33537.1 - 0.1 11.9 0.0 2.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Clathrin PF00637.20 PFH33538.1 - 2.7e-07 30.6 0.1 1.1 9.1 0.0 3.4 2 1 1 3 3 3 3 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 PFH33538.1 - 5.7e-07 28.9 0.6 0.00029 20.0 0.3 3.6 4 0 0 4 4 4 1 Coatomer WD associated region ANAPC4_WD40 PF12894.7 PFH33538.1 - 3.2e-06 27.3 1.2 0.52 10.6 0.0 5.3 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_7 PF13176.6 PFH33538.1 - 0.00032 20.5 5.6 0.48 10.6 0.1 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 PFH33538.1 - 0.0093 15.6 0.3 0.18 11.5 0.0 2.8 2 0 0 2 2 2 1 TPR repeat Cytochrom_CIII PF02085.16 PFH33538.1 - 0.025 14.9 2.1 0.079 13.3 2.1 1.8 1 0 0 1 1 1 0 Class III cytochrome C family TPR_1 PF00515.28 PFH33538.1 - 0.06 13.2 0.1 3.6 7.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH33538.1 - 0.12 13.1 0.3 2.6 8.9 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1451 PF07295.11 PFH33538.1 - 0.17 11.9 1.6 0.45 10.5 1.6 1.7 1 0 0 1 1 1 0 Zinc-ribbon containing domain Cytochrome_C7 PF14522.6 PFH33538.1 - 5.4 7.1 8.6 15 5.7 8.6 1.8 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c TPH PF13868.6 PFH33539.1 - 5.7e-09 35.0 141.3 5.7e-09 35.0 141.3 2.4 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Syja_N PF02383.18 PFH33540.1 - 3.4e-49 167.9 0.0 1e-47 163.0 0.0 2.1 2 0 0 2 2 2 2 SacI homology domain WD40 PF00400.32 PFH33541.1 - 0.00027 21.7 0.3 17 6.4 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat zf_CCCH_4 PF18345.1 PFH33541.1 - 0.0004 20.3 6.8 0.0009 19.2 6.8 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 PFH33541.1 - 0.0027 17.4 7.3 0.006 16.4 7.3 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 PFH33541.1 - 0.0051 16.7 5.4 0.0051 16.7 5.4 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WD40_like PF17005.5 PFH33541.1 - 0.28 10.5 0.0 2.5 7.4 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain CAP_N PF01213.19 PFH33541.1 - 0.45 10.0 1.4 0.67 9.4 1.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DnaJ PF00226.31 PFH33542.1 - 4.6e-21 74.7 2.5 1.1e-20 73.6 2.5 1.6 1 0 0 1 1 1 1 DnaJ domain WTX PF09422.10 PFH33542.1 - 0.024 13.7 5.4 0.029 13.4 5.4 1.1 1 0 0 1 1 1 0 WTX protein Chromo PF00385.24 PFH33544.1 - 5e-10 39.1 0.1 5e-10 39.1 0.1 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Robl_LC7 PF03259.17 PFH33544.1 - 2.2 8.1 4.2 0.57 10.0 0.2 2.1 2 0 0 2 2 2 0 Roadblock/LC7 domain Med30 PF11315.8 PFH33545.1 - 0.0015 18.8 9.1 0.085 13.0 0.1 3.6 4 0 0 4 4 4 2 Mediator complex subunit 30 HsbA PF12296.8 PFH33545.1 - 0.082 13.3 0.9 9.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Pam17 PF08566.10 PFH33545.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Dynactin_p22 PF07426.11 PFH33545.1 - 0.2 11.5 10.9 2.9 7.7 0.1 3.9 4 0 0 4 4 4 0 Dynactin subunit p22 CorA PF01544.18 PFH33545.1 - 9 5.5 8.3 1.8 7.8 1.6 2.8 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein ABC_transp_aux PF09822.9 PFH33547.1 - 3.4e-06 26.7 0.0 5.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system Peptidase_C97 PF05903.14 PFH33548.1 - 7.1e-32 110.3 0.0 1.1e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain GDWWSH PF15667.5 PFH33548.1 - 0.28 10.6 5.9 0.17 11.3 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function with motif GDWWSH DEAD PF00270.29 PFH33550.1 - 7.8e-43 146.3 0.0 1.9e-42 145.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH33550.1 - 2.2e-32 111.7 0.0 1.2e-31 109.3 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH33550.1 - 0.0019 18.2 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PFH33550.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain BATS PF06968.13 PFH33550.1 - 0.17 12.0 0.0 0.41 10.8 0.0 1.6 1 1 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain PK PF00224.21 PFH33551.1 - 4.6e-145 482.9 0.8 6.8e-145 482.3 0.8 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 PFH33551.1 - 3e-30 104.8 2.2 9.6e-30 103.2 2.2 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 PFH33551.1 - 0.0022 17.1 0.7 0.019 14.1 0.0 2.4 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family HupF_HypC PF01455.18 PFH33551.1 - 0.0044 17.1 0.4 0.11 12.6 0.1 3.3 3 1 1 4 4 4 1 HupF/HypC family RMI2 PF16100.5 PFH33553.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 SAG PF04092.13 PFH33554.1 - 2.2e-46 157.9 23.2 3.3e-24 86.1 7.5 2.1 2 0 0 2 2 2 2 SRS domain DEAD PF00270.29 PFH33555.1 - 6.8e-37 126.9 0.2 1.1e-36 126.2 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH33555.1 - 1e-27 96.7 2.4 1.7e-26 92.8 0.2 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH33555.1 - 4.3e-06 26.8 0.2 8.1e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PFH33555.1 - 0.0021 17.5 0.1 0.004 16.5 0.1 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.6 PFH33556.1 - 1.9e-41 142.1 0.1 9e-41 139.9 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 PFH33556.1 - 2.1e-32 112.1 0.0 8.2e-18 64.6 0.0 4.0 3 1 0 3 3 3 3 DEAD_2 HBB PF06777.11 PFH33556.1 - 8.1e-28 97.4 4.4 3.4e-19 69.3 0.1 3.6 3 0 0 3 3 3 3 Helical and beta-bridge domain ResIII PF04851.15 PFH33556.1 - 3.3e-06 27.2 0.0 0.0003 20.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PFH33556.1 - 0.022 14.5 0.2 0.45 10.3 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase SR-25 PF10500.9 PFH33556.1 - 0.022 14.4 13.1 0.018 14.6 10.4 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AAA_22 PF13401.6 PFH33556.1 - 0.044 14.1 0.1 20 5.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF755 PF05501.11 PFH33556.1 - 0.096 13.0 7.0 0.27 11.5 7.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CCDC106 PF15794.5 PFH33556.1 - 0.13 11.9 5.0 0.25 11.0 5.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Flavi_DEAD PF07652.14 PFH33556.1 - 0.24 11.4 0.2 5.7 6.9 0.1 2.3 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_11 PF13086.6 PFH33556.1 - 0.44 10.3 3.2 0.96 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AF-4 PF05110.13 PFH33556.1 - 5.7 4.9 11.5 8.5 4.3 11.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein WD40 PF00400.32 PFH33557.1 - 1.1e-46 155.8 29.0 2e-11 44.2 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH33557.1 - 6.3e-13 48.8 2.3 0.015 15.6 0.0 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PFH33557.1 - 3.8e-07 29.7 0.0 0.00072 19.0 0.0 2.6 2 1 1 3 3 3 3 WD40-like domain eIF2A PF08662.11 PFH33557.1 - 9e-07 29.0 0.6 0.07 13.0 0.0 3.4 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PFH33557.1 - 0.014 14.3 0.1 3.2 6.6 0.0 3.1 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PFH33557.1 - 0.025 13.3 15.1 0.31 9.6 0.1 5.0 1 1 4 6 6 6 0 Nucleoporin Nup120/160 Gmad1 PF10647.9 PFH33557.1 - 0.026 14.3 0.4 8.9 6.0 0.5 2.9 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain PD40 PF07676.12 PFH33557.1 - 0.11 12.5 0.1 81 3.3 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat GpcrRhopsn4 PF10192.9 PFH33558.1 - 1.3e-09 37.8 5.0 2.6e-09 36.9 5.0 1.4 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 PFH33558.1 - 1.9e-07 30.6 12.6 2.7e-07 30.2 12.6 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor CIAPIN1 PF05093.13 PFH33559.1 - 4.6e-20 72.0 17.5 4.3e-17 62.5 4.0 2.5 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis A_amylase_inhib PF01356.19 PFH33559.1 - 0.038 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Alpha amylase inhibitor MRP_L53 PF10780.9 PFH33560.1 - 0.034 14.3 0.0 0.067 13.4 0.0 1.5 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 Amidase_2 PF01510.25 PFH33560.1 - 0.093 13.2 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase DUF4761 PF15958.5 PFH33561.1 - 0.2 11.8 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) Fis1_TPR_C PF14853.6 PFH33561.1 - 0.21 11.7 0.9 0.26 11.4 0.0 1.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat CTP_transf_like PF01467.26 PFH33562.1 - 1e-32 113.3 0.1 2.2e-32 112.2 0.1 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like HA2 PF04408.23 PFH33564.1 - 3.2e-20 72.4 0.1 7.7e-20 71.2 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PFH33564.1 - 4.9e-16 58.9 0.0 1e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PFH33564.1 - 1.3e-10 41.6 0.0 3.3e-09 37.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PFH33564.1 - 1.4e-07 31.9 0.0 3.4e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 PFH33564.1 - 3.7e-07 30.1 0.0 7.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 PFH33564.1 - 0.0017 18.7 0.1 0.006 17.0 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 PFH33564.1 - 0.0029 18.2 0.6 0.0071 16.9 0.2 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PFH33564.1 - 0.0031 17.9 0.2 0.01 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PFH33564.1 - 0.0031 17.3 0.0 0.0086 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PFH33564.1 - 0.0095 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 PFH33564.1 - 0.023 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 PFH33564.1 - 0.027 14.2 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 PFH33564.1 - 0.036 14.1 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 PFH33564.1 - 0.061 13.2 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Helicase Flavi_DEAD PF07652.14 PFH33564.1 - 0.097 12.6 0.0 0.24 11.4 0.0 1.6 1 1 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 PFH33564.1 - 0.11 13.0 0.1 2.3 8.7 0.1 2.7 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 PFH33564.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Herpes_ori_bp PF02399.15 PFH33564.1 - 0.2 9.6 0.0 0.3 9.1 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein GTP_EFTU PF00009.27 PFH33565.1 - 8.4e-27 94.0 0.1 1.7e-17 63.6 0.1 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PFH33565.1 - 2.9e-07 30.8 0.1 7.9e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PFH33565.1 - 3.6e-06 27.1 0.0 2.1e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 PFH33565.1 - 0.00064 19.4 0.7 0.0095 15.5 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 PFH33565.1 - 0.0019 18.0 0.5 0.17 11.6 0.2 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 PFH33565.1 - 0.0041 16.6 0.1 0.65 9.4 0.0 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PFH33565.1 - 0.022 14.7 0.4 0.057 13.3 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase DUF1999 PF09390.10 PFH33565.1 - 0.11 12.1 0.4 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1999) LRR_4 PF12799.7 PFH33566.1 - 9.6e-06 25.9 17.4 0.00046 20.5 1.0 2.9 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PFH33566.1 - 0.00031 20.3 1.2 0.00058 19.4 1.2 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PFH33566.1 - 0.01 15.6 10.1 0.02 14.7 4.8 3.1 2 1 1 3 3 3 0 Leucine rich repeat DUF1887 PF09002.11 PFH33566.1 - 0.064 11.9 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) LRR_6 PF13516.6 PFH33566.1 - 0.98 9.6 5.4 2.6 8.3 0.3 2.8 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 PFH33566.1 - 5.3 8.0 6.6 5.3 8.0 0.3 3.1 2 1 0 2 2 2 0 Leucine Rich Repeat WD40_4 PF16300.5 PFH33567.1 - 9.9e-19 67.0 0.3 1.9e-18 66.0 0.3 1.5 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 PFH33567.1 - 2.7e-10 40.0 0.0 1.6e-09 37.5 0.0 2.3 3 0 0 3 3 1 1 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 PFH33567.1 - 1.4e-06 28.5 0.7 0.018 15.3 0.3 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cnn_1N PF07989.11 PFH33567.1 - 1.5e-06 28.2 5.0 1.5e-06 28.2 5.0 3.7 2 1 1 3 3 2 2 Centrosomin N-terminal motif 1 Shugoshin_N PF07558.11 PFH33567.1 - 1e-05 25.3 15.1 0.00069 19.4 0.8 4.2 3 1 1 4 4 4 2 Shugoshin N-terminal coiled-coil region ZapB PF06005.12 PFH33567.1 - 2.2e-05 24.8 29.9 0.0079 16.6 6.9 4.0 3 1 1 4 4 3 2 Cell division protein ZapB bZIP_1 PF00170.21 PFH33567.1 - 9.3e-05 22.4 26.7 0.022 14.9 8.1 4.4 3 2 1 4 4 4 2 bZIP transcription factor bZIP_2 PF07716.15 PFH33567.1 - 0.00015 21.8 29.9 0.0024 17.9 8.1 4.7 3 2 2 5 5 5 1 Basic region leucine zipper ATG16 PF08614.11 PFH33567.1 - 0.0008 19.7 47.1 0.0044 17.3 14.1 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) ABC_tran_CTD PF16326.5 PFH33567.1 - 0.0011 19.2 24.3 0.023 14.9 1.9 4.1 3 1 1 4 4 4 2 ABC transporter C-terminal domain Leu_zip PF15294.6 PFH33567.1 - 0.0023 17.5 5.9 0.0023 17.5 5.9 2.3 1 1 1 2 2 2 1 Leucine zipper ADIP PF11559.8 PFH33567.1 - 0.005 16.9 27.7 0.047 13.8 4.0 3.3 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 PFH33567.1 - 0.0051 17.1 18.2 0.41 11.0 0.8 4.1 3 1 0 3 3 3 1 TSC-22/dip/bun family Ge1_WD40 PF16529.5 PFH33567.1 - 0.0058 15.6 0.1 0.34 9.8 0.0 2.5 1 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 PFH33567.1 - 0.007 17.2 11.3 0.29 12.1 0.0 4.3 5 0 0 5 5 3 2 WD domain, G-beta repeat TMF_TATA_bd PF12325.8 PFH33567.1 - 0.0073 16.5 4.2 0.0073 16.5 4.2 2.6 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding SIKE PF05769.11 PFH33567.1 - 0.0083 16.1 3.5 0.0083 16.1 3.5 2.5 1 1 0 2 2 2 1 SIKE family Pox_A_type_inc PF04508.12 PFH33567.1 - 0.0098 15.7 20.0 0.098 12.5 0.2 5.6 3 2 2 5 5 5 1 Viral A-type inclusion protein repeat eIF2A PF08662.11 PFH33567.1 - 0.014 15.3 0.1 0.39 10.6 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A SHE3 PF17078.5 PFH33567.1 - 0.015 15.0 13.1 0.051 13.3 13.1 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 HALZ PF02183.18 PFH33567.1 - 0.023 14.9 19.3 2.5 8.4 0.7 4.6 3 1 1 4 4 4 0 Homeobox associated leucine zipper DivIC PF04977.15 PFH33567.1 - 0.026 14.3 27.0 0.1 12.4 2.6 4.1 2 2 1 4 4 4 0 Septum formation initiator Nnf1 PF03980.14 PFH33567.1 - 0.026 14.9 17.8 0.073 13.5 13.4 2.8 2 0 0 2 2 2 0 Nnf1 GAS PF13851.6 PFH33567.1 - 0.03 13.7 24.4 0.21 10.9 24.4 2.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 PFH33567.1 - 0.03 14.4 29.4 3.2 7.8 19.8 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 PFH33567.1 - 0.031 14.1 19.8 0.17 11.7 7.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Uds1 PF15456.6 PFH33567.1 - 0.032 14.4 21.6 0.34 11.1 8.5 2.3 1 1 1 2 2 2 0 Up-regulated During Septation Fez1 PF06818.15 PFH33567.1 - 0.036 14.5 21.3 0.065 13.7 21.3 1.4 1 0 0 1 1 1 0 Fez1 HemX PF04375.14 PFH33567.1 - 0.038 13.3 18.1 0.016 14.5 2.1 2.3 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase FAM76 PF16046.5 PFH33567.1 - 0.089 12.1 13.0 0.18 11.1 13.0 1.4 1 0 0 1 1 1 0 FAM76 protein Mto2_bdg PF12808.7 PFH33567.1 - 0.12 12.7 24.7 0.25 11.6 0.4 4.3 2 1 2 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Prefoldin_2 PF01920.20 PFH33567.1 - 0.12 12.3 25.1 2.2 8.3 12.1 3.3 2 1 0 2 2 2 0 Prefoldin subunit M_domain PF12938.7 PFH33567.1 - 0.14 12.0 0.8 0.29 10.9 0.8 1.5 1 0 0 1 1 1 0 M domain of GW182 FlaC_arch PF05377.11 PFH33567.1 - 0.15 12.5 15.4 1.2 9.6 0.3 4.1 2 1 1 4 4 4 0 Flagella accessory protein C (FlaC) PRKG1_interact PF15898.5 PFH33567.1 - 0.18 12.7 24.8 1.8 9.5 0.1 3.8 3 1 1 4 4 3 0 cGMP-dependent protein kinase interacting domain HSBP1 PF06825.12 PFH33567.1 - 0.21 11.5 5.0 3.5 7.6 0.1 3.0 3 0 0 3 3 2 0 Heat shock factor binding protein 1 DUF4763 PF15960.5 PFH33567.1 - 0.23 10.7 17.9 2.6 7.3 0.3 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) MAD PF05557.13 PFH33567.1 - 0.25 9.6 23.9 2.2 6.6 24.0 1.9 1 1 0 1 1 1 0 Mitotic checkpoint protein BRE1 PF08647.11 PFH33567.1 - 0.35 11.0 23.1 5.3 7.2 11.0 2.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Swi5 PF07061.11 PFH33567.1 - 0.36 10.9 17.3 2.8 8.1 1.1 3.7 2 1 1 3 3 3 0 Swi5 YscO PF07321.12 PFH33567.1 - 0.4 10.6 27.0 1.3 9.0 17.9 3.0 1 1 1 2 2 2 0 Type III secretion protein YscO VGPC1_C PF16799.5 PFH33567.1 - 0.41 10.7 5.1 5.5 7.0 0.0 3.0 3 0 0 3 3 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Phage_GP20 PF06810.11 PFH33567.1 - 0.49 10.2 18.2 3.9 7.3 0.7 3.2 1 1 1 3 3 3 0 Phage minor structural protein GP20 CCDC92 PF14916.6 PFH33567.1 - 0.55 10.0 9.2 2 8.3 0.3 4.2 3 2 0 3 3 3 0 Coiled-coil domain of unknown function SlyX PF04102.12 PFH33567.1 - 0.58 10.8 19.6 0.7 10.5 2.4 3.9 1 1 2 3 3 3 0 SlyX Exonuc_VII_L PF02601.15 PFH33567.1 - 0.66 9.5 13.7 1.1 8.8 13.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4686 PF15742.5 PFH33567.1 - 0.75 8.9 25.0 1.2 8.2 11.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) Csm1_N PF18504.1 PFH33567.1 - 0.86 10.0 25.3 6.2 7.2 3.1 4.0 2 1 2 4 4 4 0 Csm1 N-terminal domain Rx_N PF18052.1 PFH33567.1 - 0.89 9.9 13.2 1.3 9.3 1.4 3.3 2 1 0 3 3 3 0 Rx N-terminal domain DUF1664 PF07889.12 PFH33567.1 - 0.89 9.6 9.6 0.43 10.6 1.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 PFH33567.1 - 0.9 10.1 32.2 3.9 8.0 20.5 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region JAKMIP_CC3 PF16034.5 PFH33567.1 - 0.94 9.4 22.9 3.2 7.7 22.9 1.8 1 1 0 1 1 1 0 JAKMIP CC3 domain Atg14 PF10186.9 PFH33567.1 - 1 8.4 23.9 0.31 10.1 10.1 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 PFH33567.1 - 1.2 9.8 24.8 2.8 8.6 9.9 3.9 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 DUF3209 PF11483.8 PFH33567.1 - 1.6 9.2 9.9 0.75 10.3 4.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3209) GIT_CC PF16559.5 PFH33567.1 - 1.7 8.6 15.7 5.2 7.0 0.1 4.5 4 1 0 4 4 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Wtap PF17098.5 PFH33567.1 - 1.7 8.5 22.7 0.73 9.7 3.9 3.6 2 1 0 3 3 3 0 WTAP/Mum2p family CLZ PF16526.5 PFH33567.1 - 1.8 9.0 21.6 2.4 8.6 0.4 3.6 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Syntaxin-6_N PF09177.11 PFH33567.1 - 2 9.0 17.1 5.7 7.6 7.5 3.2 1 1 2 3 3 2 0 Syntaxin 6, N-terminal DUF3573 PF12097.8 PFH33567.1 - 2.3 7.0 3.4 1.3 7.8 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) MPS2 PF17060.5 PFH33567.1 - 2.3 7.4 11.1 3.7 6.7 11.1 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF4472 PF14739.6 PFH33567.1 - 2.4 8.9 21.1 12 6.6 9.5 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Rootletin PF15035.6 PFH33567.1 - 2.4 8.1 21.7 1.5 8.8 14.1 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion KLRAQ PF10205.9 PFH33567.1 - 2.5 8.4 15.6 0.69 10.2 7.7 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF3138 PF11336.8 PFH33567.1 - 3 6.4 11.5 0.37 9.4 4.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Occludin_ELL PF07303.13 PFH33567.1 - 3.4 8.5 11.0 4.3 8.1 6.0 2.8 1 1 2 3 3 3 0 Occludin homology domain Spc7 PF08317.11 PFH33567.1 - 3.5 6.4 27.9 1.6 7.5 2.6 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 PFH33567.1 - 3.6 7.2 22.3 11 5.5 7.0 3.2 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain KxDL PF10241.9 PFH33567.1 - 3.6 7.9 9.0 6.2 7.2 0.6 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein HAUS-augmin3 PF14932.6 PFH33567.1 - 4.3 6.8 21.7 0.35 10.4 14.3 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Tropomyosin_1 PF12718.7 PFH33567.1 - 4.5 7.4 28.5 20 5.3 6.7 3.1 1 1 2 3 3 3 0 Tropomyosin like DivIVA PF05103.13 PFH33567.1 - 4.7 7.3 20.4 12 6.0 0.3 2.7 2 1 0 2 2 2 0 DivIVA protein KASH_CCD PF14662.6 PFH33567.1 - 4.9 6.9 27.8 0.78 9.5 9.3 2.8 2 1 1 3 3 2 0 Coiled-coil region of CCDC155 or KASH AKNA PF12443.8 PFH33567.1 - 5.2 7.8 10.2 1.7 9.4 2.1 2.8 1 1 1 2 2 2 0 AT-hook-containing transcription factor JIP_LZII PF16471.5 PFH33567.1 - 5.2 7.3 20.3 1.6 8.9 2.0 4.1 4 0 0 4 4 3 0 JNK-interacting protein leucine zipper II DUF4201 PF13870.6 PFH33567.1 - 5.4 6.7 20.8 79 2.9 18.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.8 PFH33567.1 - 5.4 7.1 28.6 0.42 10.7 5.8 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 PFH33567.1 - 5.8 6.2 23.9 7.2 5.9 2.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 PFH33567.1 - 6.2 7.0 27.5 4.3 7.5 12.5 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.22 PFH33567.1 - 6.6 7.0 23.7 31 4.8 4.8 3.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LPP PF04728.13 PFH33567.1 - 8.3 6.9 14.9 12 6.3 1.0 4.0 3 1 0 3 3 3 0 Lipoprotein leucine-zipper NYD-SP28_assoc PF14775.6 PFH33567.1 - 8.4 6.6 14.3 11 6.2 0.3 3.6 3 0 0 3 3 3 0 Sperm tail C-terminal domain Ax_dynein_light PF10211.9 PFH33567.1 - 8.7 6.2 25.7 12 5.8 5.2 3.2 1 1 1 2 2 2 0 Axonemal dynein light chain Lectin_N PF03954.14 PFH33567.1 - 9.5 6.0 10.3 6.3 6.6 0.8 3.1 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain WD40 PF00400.32 PFH33568.1 - 1.5e-05 25.7 1.0 29 5.8 0.0 5.6 4 1 2 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH33568.1 - 0.00027 21.2 0.0 0.47 10.8 0.0 3.8 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Proteasome_A_N PF10584.9 PFH33568.1 - 0.0075 15.9 0.2 3.7 7.3 0.0 3.2 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature eIF2A PF08662.11 PFH33568.1 - 0.18 11.6 0.0 26 4.6 0.0 3.3 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A LysM PF01476.20 PFH33569.1 - 4.7e-06 26.6 0.0 7.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 LysM domain GYF PF02213.16 PFH33572.1 - 0.00022 20.8 0.6 0.00022 20.8 0.6 1.9 2 0 0 2 2 2 1 GYF domain Nucleotid_trans PF03407.16 PFH33572.1 - 0.053 13.5 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DDHD PF02862.17 PFH33572.1 - 7 6.7 6.1 12 5.9 1.8 2.3 2 0 0 2 2 2 0 DDHD domain Kinase-like PF14531.6 PFH33573.1 - 4e-55 187.2 0.0 5.1e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH33573.1 - 2.3e-21 76.4 0.0 3.3e-16 59.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33573.1 - 0.00031 20.1 0.0 0.0029 16.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PFH33573.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AFG1_ATPase PF03969.16 PFH33574.1 - 5.6e-92 308.4 0.2 4e-89 299.0 0.3 3.0 3 0 0 3 3 3 2 AFG1-like ATPase AAA PF00004.29 PFH33574.1 - 0.0014 19.0 0.0 0.0046 17.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 PFH33574.1 - 0.0022 17.9 0.4 0.0088 15.9 0.0 2.1 2 1 1 3 3 3 1 Bacterial dnaA protein NACHT PF05729.12 PFH33574.1 - 0.037 14.0 0.0 0.14 12.0 0.0 2.0 3 0 0 3 3 3 0 NACHT domain Barstar PF01337.18 PFH33574.1 - 0.064 13.3 0.0 2.4 8.3 0.0 2.7 2 0 0 2 2 2 0 Barstar (barnase inhibitor) ATPase_2 PF01637.18 PFH33574.1 - 0.067 13.1 0.1 0.25 11.2 0.0 1.8 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 PFH33574.1 - 0.12 12.6 0.6 3.3 8.0 0.6 2.8 2 1 0 2 2 2 0 AAA domain DUF1674 PF07896.12 PFH33575.1 - 4.3e-09 36.7 0.1 1.1e-08 35.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) OTU PF02338.19 PFH33577.1 - 4.5e-05 24.0 0.0 0.00039 20.9 0.0 2.1 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PFH33577.1 - 0.0025 17.3 0.1 2.1 7.7 0.1 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain ZZ PF00569.17 PFH33578.1 - 2.7e-07 30.3 11.6 5.1e-07 29.4 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 PFH33578.1 - 5.9e-06 26.4 0.5 4.1e-05 23.7 0.1 2.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PFH33578.1 - 0.074 13.3 0.4 1.3 9.3 0.0 3.0 4 0 0 4 4 4 0 Myb-like DNA-binding domain DER1 PF04511.15 PFH33579.1 - 1.5e-39 135.9 15.4 1.7e-39 135.7 15.4 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 PFH33579.1 - 1.8e-05 24.8 16.7 2.7e-05 24.2 16.7 1.2 1 0 0 1 1 1 1 Rhomboid family zf-C3HC4_3 PF13920.6 PFH33583.1 - 6.8e-10 38.6 11.0 1.2e-09 37.9 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PFH33583.1 - 3.1e-07 30.1 11.4 6.2e-07 29.1 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PFH33583.1 - 6.4e-07 29.1 10.3 1.3e-06 28.1 10.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PFH33583.1 - 4.8e-06 26.4 13.0 1e-05 25.3 13.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH33583.1 - 1.1e-05 25.3 7.2 3.3e-05 23.8 7.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 PFH33583.1 - 1.5e-05 25.2 11.9 2.8e-05 24.3 11.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PFH33583.1 - 0.00071 19.5 13.6 0.0014 18.6 13.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-UDP PF14569.6 PFH33583.1 - 0.00076 19.5 4.2 0.0016 18.5 4.2 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 PFH33583.1 - 0.0022 17.7 9.0 0.005 16.6 9.0 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain IFT57 PF10498.9 PFH33583.1 - 0.0028 16.7 0.9 0.0028 16.7 0.9 4.8 3 2 1 4 4 2 1 Intra-flagellar transport protein 57 zf-C3HC4_4 PF15227.6 PFH33583.1 - 0.036 14.2 10.8 0.017 15.3 8.2 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PFH33583.1 - 0.073 13.4 7.9 0.23 11.8 7.9 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 PFH33583.1 - 0.14 12.3 7.2 0.31 11.2 7.2 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ribbon_3 PF13248.6 PFH33583.1 - 1 8.9 3.9 2.1 7.9 3.3 1.9 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 PFH33583.1 - 3.8 7.6 6.5 11 6.2 6.5 1.7 1 0 0 1 1 1 0 Double zinc ribbon YscW PF09619.10 PFH33584.1 - 0.0063 16.9 0.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 2 Type III secretion system lipoprotein chaperone (YscW) Ribosomal_60s PF00428.19 PFH33584.1 - 0.68 10.6 5.6 8.1 7.1 1.2 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Sas10 PF09368.10 PFH33585.1 - 1.4e-23 83.1 7.1 1.4e-23 83.1 7.1 3.2 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 PFH33585.1 - 2.8e-21 75.9 1.5 2.8e-21 75.9 1.5 3.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family SDA1 PF05285.12 PFH33585.1 - 0.0046 16.4 25.0 0.0046 16.4 25.0 4.0 2 1 0 2 2 2 1 SDA1 Prenyltransf PF01255.19 PFH33586.1 - 3.9e-60 203.2 0.0 5.6e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase HTH_Tnp_Tc5 PF03221.16 PFH33586.1 - 0.24 11.4 1.2 0.34 11.0 0.1 1.8 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain DEAD PF00270.29 PFH33588.1 - 2.5e-15 56.7 0.0 4.4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 PFH33588.1 - 4.6e-05 23.5 0.0 0.0002 21.4 0.0 1.9 1 1 0 1 1 1 1 rRNA-processing arch domain C2 PF00168.30 PFH33590.1 - 1.2e-10 41.5 0.2 2e-09 37.6 0.2 2.4 1 1 0 1 1 1 1 C2 domain Transglut_core PF01841.19 PFH33590.1 - 0.033 14.6 0.1 0.079 13.4 0.1 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF5136 PF17199.4 PFH33590.1 - 0.078 12.7 0.4 0.17 11.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF5136) DUF553 PF04473.12 PFH33590.1 - 0.095 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like domain BUD22 PF09073.10 PFH33590.1 - 1.8 7.8 15.1 0.11 11.8 7.3 2.0 2 0 0 2 2 2 0 BUD22 AAA_33 PF13671.6 PFH33592.1 - 4.4e-05 23.7 0.1 0.005 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PFH33592.1 - 8.1e-05 23.2 0.1 0.0016 19.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PFH33592.1 - 0.0071 16.7 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 PFH33592.1 - 0.0097 15.8 0.0 0.061 13.2 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.18 PFH33592.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Metal_resist PF13801.6 PFH33592.1 - 0.016 15.4 0.4 0.016 15.4 0.4 2.2 2 0 0 2 2 1 0 Heavy-metal resistance Zeta_toxin PF06414.12 PFH33592.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 PFH33592.1 - 0.021 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 dNK PF01712.19 PFH33592.1 - 0.023 14.6 0.0 3.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase APS_kinase PF01583.20 PFH33592.1 - 0.031 14.2 0.1 3 7.7 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 PFH33592.1 - 0.044 13.0 0.0 0.067 12.4 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Thymidylate_kin PF02223.17 PFH33592.1 - 0.054 13.2 0.0 0.77 9.4 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.6 PFH33592.1 - 0.056 13.7 0.0 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 PFH33592.1 - 0.056 12.7 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 PFH33592.1 - 0.065 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 PFH33592.1 - 0.073 13.5 0.2 0.2 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PFH33592.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 PFH33592.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 PFH33592.1 - 0.14 12.3 0.1 4.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_22 PF13401.6 PFH33592.1 - 0.21 11.9 0.0 0.4 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 PFH33592.1 - 0.22 11.2 0.0 10 5.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PseudoU_synth_2 PF00849.22 PFH33593.1 - 1.6e-20 73.8 0.0 2.9e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Cullin PF00888.22 PFH33595.1 - 2.4e-129 432.7 1.4 3.5e-129 432.2 1.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 PFH33595.1 - 2.4e-22 78.7 0.5 5.5e-22 77.6 0.5 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF4667 PF15700.5 PFH33595.1 - 0.015 15.4 6.1 0.025 14.7 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Period_C PF12114.8 PFH33595.1 - 0.028 14.0 7.9 0.072 12.7 7.9 1.6 1 0 0 1 1 1 0 Period protein 2/3C-terminal region RAP1 PF07218.11 PFH33595.1 - 1.1 7.5 11.2 1.6 6.9 11.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SUR7 PF06687.12 PFH33596.1 - 0.053 13.1 0.8 8 6.0 0.7 2.1 2 0 0 2 2 2 0 SUR7/PalI family DUF4407 PF14362.6 PFH33597.1 - 0.0024 17.3 19.8 0.0063 15.9 19.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) AAA_9 PF12781.7 PFH33597.1 - 3.7 6.6 5.6 6.9 5.7 5.6 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region LPP PF04728.13 PFH33597.1 - 6.9 7.2 8.5 14 6.2 4.8 3.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Fasciclin PF02469.22 PFH33598.1 - 0.0023 18.1 0.0 11 6.2 0.0 4.1 4 0 0 4 4 4 2 Fasciclin domain zf-C3HC4 PF00097.25 PFH33598.1 - 0.2 11.6 0.5 0.39 10.6 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 PFH33599.1 - 8.2e-21 73.9 4.2 0.00031 21.5 0.1 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 PFH33599.1 - 0.0015 18.4 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A FAST_1 PF06743.15 PFH33600.1 - 0.0017 18.3 12.8 0.0048 16.8 0.1 5.0 3 1 1 5 5 5 2 FAST kinase-like protein, subdomain 1 Lipoprotein_19 PF13617.6 PFH33600.1 - 0.08 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 YnbE-like lipoprotein SelK_SelG PF10961.8 PFH33601.1 - 2.5e-05 24.8 3.5 4.3e-05 24.0 3.3 1.6 1 1 0 1 1 1 1 Selenoprotein SelK_SelG EF-hand_8 PF13833.6 PFH33602.1 - 7.1e-09 35.4 0.8 0.0021 17.9 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 PFH33602.1 - 3.9e-08 32.3 1.2 0.049 13.2 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PFH33602.1 - 1.3e-05 24.7 0.1 0.11 12.5 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PFH33602.1 - 2.7e-05 23.5 1.2 0.018 14.5 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PFH33602.1 - 3.7e-05 24.1 0.0 0.75 10.3 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair DIM1 PF02966.16 PFH33602.1 - 0.041 13.7 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 TBP-binding PF09247.11 PFH33602.1 - 0.048 13.9 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 TATA box-binding protein binding PPR_3 PF13812.6 PFH33603.1 - 0.00011 22.2 0.2 0.00042 20.3 0.0 1.9 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_long PF17177.4 PFH33603.1 - 0.037 13.4 0.1 0.037 13.4 0.1 1.9 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 PFH33603.1 - 0.05 13.8 0.0 1.4 9.1 0.0 2.3 1 1 1 2 2 2 0 PPR repeat family GRP PF07172.11 PFH33605.1 - 6.7e-07 29.9 3.0 9e-07 29.5 3.0 1.2 1 0 0 1 1 1 1 Glycine rich protein family ISP1_C PF18161.1 PFH33606.1 - 6.8e-42 141.8 0.0 8.7e-42 141.5 0.0 1.1 1 0 0 1 1 1 1 ISP1 C-terminal ISP3_C PF18045.1 PFH33606.1 - 8.8e-41 138.2 0.0 1.1e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 ISP3 C-terminal DUF2460 PF09343.10 PFH33606.1 - 0.015 14.8 0.0 0.084 12.4 0.0 1.9 1 1 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) Spc7 PF08317.11 PFH33607.1 - 0.0017 17.3 16.3 0.0017 17.3 16.3 5.9 2 2 3 6 6 6 4 Spc7 kinetochore protein CBM_48 PF02922.18 PFH33608.1 - 7.7e-24 83.9 0.1 8.9e-23 80.5 0.0 2.7 3 0 0 3 3 3 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 PFH33608.1 - 2.2e-21 76.1 0.0 2.6e-20 72.7 0.0 2.5 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 PFH33608.1 - 2.6e-12 47.0 0.0 0.00012 21.7 0.0 3.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 PFH33608.1 - 0.0069 16.5 0.1 0.021 15.0 0.0 1.8 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain HHV-1_VABD PF16852.5 PFH33608.1 - 0.14 12.2 0.8 0.37 10.8 0.8 1.7 1 0 0 1 1 1 0 Herpes viral adaptor-to-host cellular mRNA binding domain DUF2040 PF09745.9 PFH33610.1 - 2.3e-17 63.2 8.9 3.8e-14 52.8 4.1 4.0 3 2 1 4 4 4 2 Coiled-coil domain-containing protein 55 (DUF2040) XRN_N PF03159.18 PFH33611.1 - 1.5e-50 171.9 0.0 1.4e-40 139.3 0.0 3.3 3 0 0 3 3 3 3 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PFH33611.1 - 1.6e-42 146.1 4.7 1.7e-22 80.0 0.0 2.5 3 0 0 3 3 3 2 Xrn1 helical domain DUF4556 PF15094.6 PFH33611.1 - 0.054 12.7 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) BPS1 PF05633.11 PFH33613.1 - 0.34 9.8 0.8 0.6 9.1 0.0 1.6 2 0 0 2 2 2 0 Protein BYPASS1-related TRAM_LAG1_CLN8 PF03798.16 PFH33615.1 - 7e-34 117.3 18.6 7e-34 117.3 18.6 1.5 2 0 0 2 2 2 1 TLC domain PI3_PI4_kinase PF00454.27 PFH33616.1 - 2.3e-54 184.8 0.0 5e-54 183.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 PFH33616.1 - 1.3e-51 175.9 4.4 1.4e-22 80.4 0.1 4.4 4 0 0 4 4 4 4 FAT domain FRB_dom PF08771.11 PFH33616.1 - 3e-28 98.2 0.1 9.6e-28 96.5 0.1 2.0 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 PFH33616.1 - 2e-12 46.7 0.1 5.6e-12 45.3 0.1 1.8 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 PFH33616.1 - 0.0044 17.5 4.5 0.62 10.6 0.1 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat YfiO PF13525.6 PFH33616.1 - 0.012 15.3 0.1 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Outer membrane lipoprotein TPR_7 PF13176.6 PFH33616.1 - 0.013 15.4 0.4 0.013 15.4 0.4 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 PFH33616.1 - 0.015 15.4 5.5 5.1 7.5 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 PFH33616.1 - 0.015 15.1 3.5 6 6.9 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat T2SSF PF00482.23 PFH33616.1 - 0.059 13.3 0.1 1.3 9.0 0.0 3.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F TPR_11 PF13414.6 PFH33616.1 - 0.067 12.9 1.7 0.11 12.2 0.2 2.2 2 0 0 2 2 2 0 TPR repeat DUF3385 PF11865.8 PFH33616.1 - 0.067 13.1 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF3385) ANAPC3 PF12895.7 PFH33616.1 - 0.12 12.6 1.3 15 5.9 0.1 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 PFH33616.1 - 0.23 11.4 3.4 39 4.3 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 PFH33616.1 - 0.55 10.9 11.6 0.05 14.3 0.6 3.8 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 PFH33616.1 - 0.95 10.5 15.4 0.54 11.2 0.1 5.8 6 0 0 6 6 4 0 Tetratricopeptide repeat HEAT PF02985.22 PFH33616.1 - 1.6 9.2 12.6 0.071 13.4 1.3 4.6 4 0 0 4 4 3 0 HEAT repeat TPR_6 PF13174.6 PFH33616.1 - 5.9 7.8 5.1 64 4.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat HEAT PF02985.22 PFH33617.1 - 8.8 6.9 9.4 0.83 10.1 0.3 4.3 3 0 0 3 3 3 0 HEAT repeat Tubulin PF00091.25 PFH33618.1 - 5.2e-67 225.9 0.0 7.2e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PFH33618.1 - 6e-51 171.9 0.3 1.6e-50 170.5 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 PFH33618.1 - 0.035 13.8 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Tubulin domain Methyltransf_16 PF10294.9 PFH33620.1 - 3e-20 72.7 0.0 5.3e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Profilin PF00235.19 PFH33621.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.2 1 0 0 1 1 1 1 Profilin SURF6 PF04935.12 PFH33622.1 - 5.2e-14 52.5 38.4 5.2e-14 52.5 38.4 2.3 1 1 0 2 2 2 1 Surfeit locus protein 6 ERM PF00769.19 PFH33622.1 - 0.014 15.2 25.6 0.014 15.2 25.6 3.0 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Parvo_coat_N PF08398.10 PFH33622.1 - 0.072 13.3 0.5 0.78 9.9 0.1 2.5 2 0 0 2 2 2 0 Parvovirus coat protein VP1 TraG_N PF07916.11 PFH33622.1 - 0.62 8.8 1.7 0.91 8.3 1.7 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Sod_Fe_C PF02777.18 PFH33624.1 - 1.6e-36 124.5 0.3 1.6e-36 124.5 0.3 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 PFH33624.1 - 3.9e-30 104.1 0.2 8.5e-30 103.1 0.2 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ABC_membrane PF00664.23 PFH33625.1 - 1.2e-33 117.0 12.9 2e-33 116.2 12.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PFH33625.1 - 2e-27 96.4 0.0 3.7e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 PFH33625.1 - 2.9e-05 23.4 0.0 0.00025 20.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin T2SSE PF00437.20 PFH33625.1 - 0.013 14.6 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 PFH33625.1 - 0.015 15.2 1.0 0.56 10.1 0.2 2.4 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 PFH33625.1 - 0.02 15.3 0.3 0.09 13.2 0.3 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 PFH33625.1 - 0.031 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 PFH33625.1 - 0.084 12.6 0.7 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PFH33625.1 - 0.091 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3584 PF12128.8 PFH33625.1 - 0.19 9.2 0.7 0.25 8.8 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Sod_Fe_C PF02777.18 PFH33626.1 - 7.9e-39 131.9 0.3 1.1e-37 128.3 0.1 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 PFH33626.1 - 1.3e-32 112.0 0.4 2.9e-32 111.0 0.4 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DEAD PF00270.29 PFH33627.1 - 2.5e-17 63.2 0.3 4.8e-16 59.0 0.0 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH33627.1 - 2.1e-16 60.3 0.0 5.8e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH33627.1 - 6e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 PFH33627.1 - 0.0048 17.6 2.4 0.026 15.2 2.4 2.4 1 1 0 1 1 1 1 RecQ zinc-binding Yuri_gagarin PF15934.5 PFH33627.1 - 0.011 15.6 1.8 0.023 14.5 1.8 1.5 1 0 0 1 1 1 0 Yuri gagarin TMPIT PF07851.13 PFH33627.1 - 0.09 12.0 0.3 4.8 6.3 0.0 2.5 2 0 0 2 2 2 0 TMPIT-like protein SecA_DEAD PF07517.14 PFH33627.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain YabA PF06156.13 PFH33627.1 - 0.23 12.1 1.6 1 10.0 0.5 2.4 2 0 0 2 2 2 0 Initiation control protein YabA AAA_22 PF13401.6 PFH33627.1 - 1.9 8.7 4.0 0.87 9.9 0.2 2.5 3 1 0 3 3 3 0 AAA domain Nup54 PF13874.6 PFH33627.1 - 2.2 8.4 9.4 0.065 13.3 1.2 2.4 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 Rx_N PF18052.1 PFH33627.1 - 3.9 7.8 11.7 12 6.3 0.9 3.5 3 0 0 3 3 3 0 Rx N-terminal domain MFS_1 PF07690.16 PFH33628.1 - 1e-28 100.3 39.6 1.4e-21 76.9 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Prenyltrans PF00432.21 PFH33629.1 - 3.1e-48 161.2 18.1 2.3e-10 40.0 0.0 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 PFH33629.1 - 0.00027 20.1 0.0 2.5 7.1 0.0 3.5 1 1 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 PFH33629.1 - 0.00039 19.5 0.0 0.13 11.3 0.0 3.6 3 1 1 4 4 4 1 A-macroglobulin TED domain Adipogenin PF15202.6 PFH33630.1 - 2.8 8.0 4.9 0.79 9.8 0.5 2.4 2 0 0 2 2 2 0 Adipogenin DUF4881 PF16222.5 PFH33632.1 - 0.15 11.9 0.0 0.63 9.9 0.0 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4881) Dynactin_p62 PF05502.13 PFH33633.1 - 4.6e-14 52.1 12.0 2.3e-07 30.0 6.8 3.2 3 0 0 3 3 3 3 Dynactin p62 family K_channel_TID PF07941.11 PFH33633.1 - 2.8 8.5 16.7 0.15 12.6 5.9 3.2 2 1 1 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain DUF3006 PF11213.8 PFH33634.1 - 0.001 19.3 0.2 0.0039 17.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) CHS5_N PF16892.5 PFH33634.1 - 0.013 15.4 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Chitin biosynthesis protein CHS5 N-terminus Syja_N PF02383.18 PFH33635.1 - 3.1e-76 256.8 0.0 4e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Med6 PF04934.14 PFH33636.1 - 1.5e-14 53.9 0.0 2.8e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 MED6 mediator sub complex component LppC PF04348.13 PFH33636.1 - 1.3 7.8 9.9 1.7 7.4 9.9 1.1 1 0 0 1 1 1 0 LppC putative lipoprotein His_Phos_1 PF00300.22 PFH33637.1 - 2.7e-08 33.7 1.0 0.41 10.3 0.0 4.3 4 0 0 4 4 4 4 Histidine phosphatase superfamily (branch 1) ISK_Channel PF02060.15 PFH33637.1 - 0.16 11.7 1.1 0.31 10.8 1.1 1.4 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Sod_Fe_C PF02777.18 PFH33638.1 - 2.2e-36 124.1 2.0 2.2e-36 124.1 2.0 2.2 2 1 1 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 PFH33638.1 - 7.6e-35 119.2 1.7 1.5e-34 118.3 1.7 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF4279 PF14106.6 PFH33638.1 - 0.14 12.4 0.1 0.58 10.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) FF PF01846.19 PFH33639.1 - 1.1e-23 83.1 3.6 3.1e-09 36.9 0.1 6.2 5 2 0 5 5 5 3 FF domain WW PF00397.26 PFH33639.1 - 0.004 17.2 2.2 0.0078 16.3 2.2 1.5 1 0 0 1 1 1 1 WW domain DUF3323 PF11796.8 PFH33639.1 - 0.33 10.8 3.6 1.1 9.1 3.6 1.9 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) FAM176 PF14851.6 PFH33639.1 - 0.57 9.8 6.4 2.3 7.9 6.4 2.0 1 0 0 1 1 1 0 FAM176 family SpoIIIAH PF12685.7 PFH33639.1 - 1.1 9.1 15.9 1.6 8.5 0.1 2.7 3 0 0 3 3 3 0 SpoIIIAH-like protein Pkinase PF00069.25 PFH33640.1 - 3e-64 216.9 0.0 4e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33640.1 - 6e-42 143.7 0.0 8.6e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PFH33640.1 - 0.0036 16.7 0.2 0.0073 15.7 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH33640.1 - 0.017 15.1 0.2 0.017 15.1 0.2 4.9 5 1 1 6 6 6 0 Phosphotransferase enzyme family CENP-B_dimeris PF09026.10 PFH33640.1 - 1.1 9.7 4.4 1.4 9.4 0.0 3.1 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Romo1 PF10247.9 PFH33642.1 - 5.2e-16 58.8 11.0 7.3e-16 58.3 11.0 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 DUF4202 PF13875.6 PFH33643.1 - 0.043 13.7 0.6 0.085 12.8 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) GTP1_OBG PF01018.22 PFH33644.1 - 5.6e-22 78.0 7.4 5.2e-11 42.4 0.4 3.3 2 1 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 PFH33644.1 - 5.8e-21 74.7 0.0 9.7e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PFH33644.1 - 3.8e-09 36.2 0.0 3.4e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Ploopntkinase3 PF18751.1 PFH33644.1 - 0.03 14.3 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Dynamin_N PF00350.23 PFH33644.1 - 0.096 12.7 0.0 15 5.6 0.0 2.2 1 1 1 2 2 2 0 Dynamin family Ribosomal_S15 PF00312.22 PFH33645.1 - 1.1e-20 73.5 1.6 1.7e-20 73.0 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 TGT PF01702.18 PFH33647.1 - 1.2e-116 389.7 0.0 4.5e-89 299.0 0.0 3.1 3 0 0 3 3 3 3 Queuine tRNA-ribosyltransferase Rpr2 PF04032.16 PFH33648.1 - 4.6e-06 26.8 0.0 1.6e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Peptidase_C97 PF05903.14 PFH33649.1 - 2.5e-22 79.4 0.0 3.7e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Radical_SAM PF04055.21 PFH33651.1 - 6e-24 85.3 0.0 1e-23 84.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 PFH33651.1 - 2.2e-09 37.5 0.0 7.8e-09 35.8 0.0 2.0 1 1 0 1 1 1 1 Wyosine base formation BppL_N PF18338.1 PFH33651.1 - 0.097 12.5 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 Lower baseplate protein N-terminal domain zf-RING_2 PF13639.6 PFH33652.1 - 2.8e-11 43.6 8.4 6.9e-11 42.3 8.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PFH33652.1 - 1.5e-08 34.2 4.9 3.6e-08 33.0 4.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PFH33652.1 - 2.5e-08 33.6 6.5 6.1e-08 32.4 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH33652.1 - 8.9e-08 32.0 4.2 1.9e-07 31.0 4.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PFH33652.1 - 8.4e-07 28.8 6.5 2.1e-06 27.5 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PFH33652.1 - 8.7e-07 29.1 5.9 2.7e-06 27.6 5.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PFH33652.1 - 1.7e-06 27.9 8.1 1.7e-06 27.9 8.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PFH33652.1 - 0.0012 18.6 5.5 0.0032 17.3 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PFH33652.1 - 0.0031 17.3 5.7 0.0077 16.1 5.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PFH33652.1 - 0.16 12.1 2.6 0.34 11.0 2.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 PFH33652.1 - 0.29 10.8 2.1 0.72 9.6 2.1 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-Nse PF11789.8 PFH33652.1 - 0.31 10.9 3.9 0.77 9.6 3.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 PFH33652.1 - 1.4 8.6 7.4 2.9 7.6 6.5 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 PFH33652.1 - 2.2 8.5 5.1 8 6.7 5.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain LMF1 PF06762.14 PFH33653.1 - 4.5e-38 131.5 6.2 3.7e-35 121.9 0.7 2.1 2 0 0 2 2 2 2 Lipase maturation factor LMF1 PF06762.14 PFH33654.1 - 2.4e-76 257.6 8.5 1.3e-59 202.5 2.9 3.1 3 0 0 3 3 3 3 Lipase maturation factor TauE PF01925.19 PFH33655.1 - 0.051 13.2 0.2 0.064 12.9 0.2 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE NDUF_B4 PF07225.12 PFH33655.1 - 0.11 12.4 0.5 1.2 9.0 0.1 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) RNA_pol_L_2 PF13656.6 PFH33656.1 - 4.8e-16 58.3 0.0 6.7e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Polysacc_synt_4 PF04669.13 PFH33656.1 - 0.059 12.9 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis RNA_pol_L PF01193.24 PFH33656.1 - 0.066 12.7 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain GlcNAc PF11397.8 PFH33659.1 - 4.3e-31 108.6 0.1 9.7e-22 77.9 0.1 4.2 3 1 0 3 3 3 3 Glycosyltransferase (GlcNAc) DUF3638 PF12340.8 PFH33660.1 - 1.4e-20 73.6 0.1 7.2e-19 68.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 PFH33660.1 - 6.6e-15 54.2 0.2 1.6e-14 53.0 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_7 PF13499.6 PFH33660.1 - 2.1e-12 47.3 0.0 1.2e-05 25.7 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH33660.1 - 2.3e-07 30.2 0.2 0.081 12.9 0.0 4.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 PFH33660.1 - 5.4e-06 25.6 0.2 0.14 11.7 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PFH33660.1 - 7.4e-05 22.5 0.0 0.0053 16.6 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PFH33660.1 - 4.3 7.0 6.2 0.32 10.6 0.1 2.5 3 0 0 3 3 3 0 EF hand Kinesin PF00225.23 PFH33661.1 - 1.9e-41 142.1 0.5 3.3e-25 88.7 0.0 3.3 3 0 0 3 3 3 3 Kinesin motor domain Troponin-I_N PF11636.8 PFH33662.1 - 0.078 12.9 6.2 1.4 9.0 1.5 3.4 2 0 0 2 2 2 0 Troponin I residues 1-32 PsbY PF06298.11 PFH33662.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) PolyA_pol PF01743.20 PFH33663.1 - 1.3e-27 96.7 0.0 4e-27 95.2 0.0 1.9 1 0 0 1 1 1 1 Poly A polymerase head domain EF-hand_7 PF13499.6 PFH33666.1 - 5.5e-11 42.8 0.7 0.00028 21.2 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH33666.1 - 8.4e-10 37.8 0.1 0.00052 19.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 PFH33666.1 - 9.8e-09 34.2 0.3 0.0027 17.1 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 PFH33666.1 - 4.6e-05 22.7 1.1 0.11 12.1 0.3 2.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PFH33666.1 - 0.0044 16.8 0.1 0.38 10.6 0.0 2.9 3 1 1 4 4 4 1 EF-hand domain pair DUF802 PF05650.11 PFH33666.1 - 0.053 14.0 1.2 0.12 12.9 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF802) p450 PF00067.22 PFH33667.1 - 2.7e-38 131.9 0.0 4e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Apt1 PF10351.9 PFH33668.1 - 0.14 10.9 4.2 0.17 10.7 4.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SWIRM-assoc_2 PF16496.5 PFH33668.1 - 0.17 10.7 10.7 0.22 10.3 10.7 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal NPR3 PF03666.13 PFH33668.1 - 2.5 6.8 10.2 3.1 6.5 10.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 PFH33668.1 - 4.1 6.1 8.8 5.1 5.8 8.8 1.1 1 0 0 1 1 1 0 Presenilin AP2 PF00847.20 PFH33669.1 - 4.2e-12 46.1 0.2 1.4e-11 44.4 0.2 2.0 1 0 0 1 1 1 1 AP2 domain Treslin_N PF15292.6 PFH33670.1 - 0.032 12.6 4.6 0.61 8.4 0.2 2.9 1 1 2 3 3 3 0 Treslin N-terminus DUF3491 PF11996.8 PFH33670.1 - 0.05 11.4 0.0 0.067 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) AMA-1 PF02430.15 PFH33671.1 - 3.9e-56 191.0 0.0 1.3e-54 185.9 0.0 2.0 1 1 0 1 1 1 1 Apical membrane antigen 1 Smg4_UPF3 PF03467.15 PFH33672.1 - 3.5e-34 118.3 1.5 4.6e-34 117.9 0.0 1.9 2 0 0 2 2 2 1 Smg-4/UPF3 family SCAMP PF04144.13 PFH33673.1 - 6.4e-09 36.4 1.9 1e-08 35.7 1.9 1.3 1 1 0 1 1 1 1 SCAMP family zf-His_Me_endon PF05551.11 PFH33674.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease GYF PF02213.16 PFH33676.1 - 3.5e-14 52.2 0.2 6.3e-14 51.4 0.2 1.4 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 PFH33676.1 - 1.1e-05 25.1 0.0 3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 PFH33677.1 - 3.7e-19 68.6 1.8 3.7e-19 68.6 1.8 3.8 3 1 0 3 3 3 1 DnaJ domain DUF3322 PF11795.8 PFH33677.1 - 0.035 14.1 2.5 0.093 12.7 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) AAA PF00004.29 PFH33678.1 - 2.6e-42 144.4 0.0 4.5e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 PFH33678.1 - 4e-22 78.0 0.1 8.6e-22 76.9 0.1 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 PFH33678.1 - 1.8e-16 59.9 3.1 1.8e-16 59.9 3.1 1.7 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 PFH33678.1 - 4.8e-08 32.7 1.7 1.4e-07 31.2 0.0 2.6 3 0 0 3 3 2 1 AAA+ lid domain AAA_16 PF13191.6 PFH33678.1 - 2.1e-06 28.2 0.0 2.8e-05 24.6 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 PFH33678.1 - 8.3e-06 25.6 0.0 1.7e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PFH33678.1 - 8.3e-06 25.8 0.0 2.8e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 PFH33678.1 - 3.7e-05 23.5 0.0 0.00015 21.5 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 PFH33678.1 - 0.00018 21.8 0.1 0.0062 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 PFH33678.1 - 0.00019 21.1 0.4 0.084 12.4 0.2 2.6 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 PFH33678.1 - 0.00069 19.8 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 PFH33678.1 - 0.00083 19.5 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 PFH33678.1 - 0.00093 19.2 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PFH33678.1 - 0.0019 18.8 0.0 0.0038 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 PFH33678.1 - 0.0027 16.9 0.0 0.0043 16.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 PFH33678.1 - 0.0042 16.3 0.0 0.0069 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 PFH33678.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 PFH33678.1 - 0.016 15.7 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 PFH33678.1 - 0.019 14.4 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 PFH33678.1 - 0.025 15.0 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 PFH33678.1 - 0.034 13.6 0.1 0.064 12.7 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 PFH33678.1 - 0.041 13.9 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 PFH33678.1 - 0.043 13.7 0.0 0.61 10.0 0.0 2.6 1 1 1 2 2 2 0 NACHT domain ATPase_2 PF01637.18 PFH33678.1 - 0.051 13.5 0.0 1.2 9.0 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea CRM1_repeat PF18777.1 PFH33678.1 - 0.054 13.0 0.8 0.1 12.1 0.8 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat AAA_28 PF13521.6 PFH33678.1 - 0.084 13.1 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PFH33678.1 - 0.089 12.5 0.0 0.42 10.3 0.0 2.1 2 1 1 3 3 3 0 Sigma-54 interaction domain AAA_30 PF13604.6 PFH33678.1 - 0.11 12.2 0.2 0.25 11.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PFH33678.1 - 0.14 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 PFH33678.1 - 0.22 10.8 0.1 1.4 8.2 0.0 2.0 1 1 1 2 2 2 0 KaiC HEAT PF02985.22 PFH33679.1 - 1.6e-14 52.8 22.2 0.0065 16.6 0.2 7.9 9 0 0 9 9 9 6 HEAT repeat HEAT_2 PF13646.6 PFH33679.1 - 7.5e-10 39.1 17.4 1.7e-05 25.1 0.7 7.2 7 3 1 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.7 PFH33679.1 - 0.0019 18.8 0.0 0.07 13.7 0.0 2.5 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region FERM_M PF00373.18 PFH33680.1 - 0.16 12.4 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 FERM central domain ANAPC3 PF12895.7 PFH33680.1 - 0.59 10.4 9.9 2.2 8.6 0.8 4.8 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 BPL_LplA_LipB PF03099.19 PFH33681.1 - 0.0012 18.7 0.0 0.031 14.2 0.0 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family V-ATPase_C PF03223.15 PFH33683.1 - 1.6e-99 333.8 0.0 1.8e-99 333.7 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF2722 PF10846.8 PFH33683.1 - 0.037 13.0 0.4 0.054 12.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) MCM PF00493.23 PFH33685.1 - 8.3e-61 204.9 0.0 4.3e-47 160.1 0.0 3.2 3 0 0 3 3 3 3 MCM P-loop domain MCM_lid PF17855.1 PFH33685.1 - 9.9e-21 74.0 0.1 2e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 PFH33685.1 - 2.3e-13 50.1 0.1 3.9e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 MCM OB domain Mg_chelatase PF01078.21 PFH33685.1 - 2.3e-06 27.1 0.3 0.00026 20.4 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PFH33685.1 - 0.00011 22.2 0.0 0.0031 17.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PFH33685.1 - 0.00035 21.0 0.7 0.0051 17.2 0.7 3.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_3 PF07726.11 PFH33685.1 - 0.016 15.0 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 PFH33685.1 - 0.079 13.1 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) CRAL_TRIO_2 PF13716.6 PFH33686.1 - 8.8e-16 58.3 0.2 1.4e-15 57.7 0.2 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.21 PFH33686.1 - 6.9e-11 42.2 0.0 1.3e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Macro domain CRAL_TRIO PF00650.20 PFH33686.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Abhydrolase_1 PF00561.20 PFH33687.1 - 0.00027 20.6 0.0 0.00095 18.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PFH33687.1 - 0.00047 20.8 0.0 0.0022 18.6 0.0 2.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PFH33687.1 - 0.0063 15.8 0.0 0.2 10.9 0.0 2.8 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 PFH33687.1 - 0.014 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 PFH33687.1 - 0.047 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain ABC_tran PF00005.27 PFH33689.1 - 1.4e-08 35.3 0.0 2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PFH33689.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system EGF_CA PF07645.15 PFH33691.1 - 6.8e-28 96.6 82.0 2.4e-09 37.3 8.8 6.3 6 0 0 6 6 6 5 Calcium-binding EGF domain EGF_3 PF12947.7 PFH33691.1 - 6.3e-14 51.9 75.2 3.1e-06 27.3 5.5 6.7 6 0 0 6 6 6 5 EGF domain cEGF PF12662.7 PFH33691.1 - 4e-13 49.0 47.4 6.9e-06 25.9 0.6 6.9 6 1 0 6 6 6 4 Complement Clr-like EGF-like EGF PF00008.27 PFH33691.1 - 2.1e-10 40.7 65.7 4.3e-07 30.1 6.3 7.2 6 1 1 7 7 7 4 EGF-like domain Plasmod_Pvs28 PF06247.11 PFH33691.1 - 3.5e-10 40.0 58.3 8.4e-06 26.0 6.8 6.5 6 0 0 6 6 6 4 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 PFH33691.1 - 3.9e-08 33.2 48.1 0.00011 22.2 7.2 5.9 5 0 0 5 5 5 4 MSP1 EGF domain 1 hEGF PF12661.7 PFH33691.1 - 0.0004 20.9 5.1 0.0004 20.9 5.1 8.3 7 2 0 7 7 7 4 Human growth factor-like EGF FXa_inhibition PF14670.6 PFH33691.1 - 0.0023 18.2 26.7 0.0062 16.8 8.3 6.2 6 0 0 6 6 6 4 Coagulation Factor Xa inhibitory site NICE-3 PF07406.11 PFH33691.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 NICE-3 protein EGF_CA PF07645.15 PFH33692.1 - 2.9e-26 91.4 72.4 1.4e-09 38.0 5.7 6.1 6 0 0 6 6 6 5 Calcium-binding EGF domain EGF_3 PF12947.7 PFH33692.1 - 4.9e-13 49.0 58.4 0.00015 21.9 6.4 6.6 5 1 0 6 6 6 5 EGF domain cEGF PF12662.7 PFH33692.1 - 1.7e-12 47.0 37.9 1.8e-05 24.6 0.7 6.2 6 0 0 6 6 6 4 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 PFH33692.1 - 3.6e-06 26.9 2.4 3.6e-06 26.9 2.4 6.2 6 0 0 6 6 6 2 MSP1 EGF domain 1 FXa_inhibition PF14670.6 PFH33692.1 - 1.9e-05 24.8 67.9 0.00077 19.7 6.3 6.6 5 1 1 6 6 6 5 Coagulation Factor Xa inhibitory site hEGF PF12661.7 PFH33692.1 - 0.00032 21.2 4.2 0.00032 21.2 4.2 7.0 7 0 0 7 7 7 3 Human growth factor-like EGF EGF PF00008.27 PFH33692.1 - 0.031 14.6 5.4 0.031 14.6 5.4 7.0 7 0 0 7 7 7 0 EGF-like domain PLDc_N PF13396.6 PFH33692.1 - 0.3 11.0 7.2 0.49 10.4 7.2 1.3 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal EGF_CA PF07645.15 PFH33693.1 - 1.6e-32 111.5 61.0 5e-12 45.8 7.6 5.3 5 0 0 5 5 5 4 Calcium-binding EGF domain EGF_3 PF12947.7 PFH33693.1 - 1e-13 51.2 52.1 1.5e-05 25.1 6.1 5.7 5 1 0 5 5 5 4 EGF domain EGF_MSP1_1 PF12946.7 PFH33693.1 - 3e-07 30.4 41.6 1.4e-05 25.0 4.0 5.3 5 0 0 5 5 5 3 MSP1 EGF domain 1 FXa_inhibition PF14670.6 PFH33693.1 - 4.1e-06 27.0 53.0 0.00021 21.5 4.3 5.7 4 1 1 5 5 5 4 Coagulation Factor Xa inhibitory site hEGF PF12661.7 PFH33693.1 - 1.6e-05 25.3 44.9 2.6e-05 24.7 3.3 6.3 6 1 0 6 6 6 3 Human growth factor-like EGF EGF PF00008.27 PFH33693.1 - 0.00049 20.3 3.7 0.00049 20.3 3.7 6.0 6 0 0 6 6 6 4 EGF-like domain cEGF PF12662.7 PFH33693.1 - 0.0027 17.6 2.7 0.0027 17.6 2.7 5.7 5 1 0 5 5 5 2 Complement Clr-like EGF-like Vps39_2 PF10367.9 PFH33694.1 - 1.1e-21 77.3 0.0 2.2e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 PFH33694.1 - 4.9e-13 49.3 0.0 1.5e-12 47.7 0.0 1.8 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 PFH33694.1 - 5.6e-05 23.0 0.0 0.00017 21.4 0.0 1.8 1 0 0 1 1 1 1 Region in Clathrin and VPS Vps39_1 PF10366.9 PFH33694.1 - 0.0032 17.7 0.1 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 TPR_10 PF13374.6 PFH33694.1 - 0.031 14.1 1.2 1.6 8.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat EGF_CA PF07645.15 PFH33695.1 - 1.7e-20 72.9 82.8 1e-09 38.4 8.4 6.4 6 0 0 6 6 6 4 Calcium-binding EGF domain EGF_3 PF12947.7 PFH33695.1 - 3.6e-14 52.6 73.5 7.9e-06 26.0 3.8 6.9 6 1 0 6 6 6 5 EGF domain EGF PF00008.27 PFH33695.1 - 1.6e-10 41.1 66.8 0.00017 21.8 7.5 7.1 7 1 0 7 7 7 5 EGF-like domain Plasmod_Pvs28 PF06247.11 PFH33695.1 - 1.8e-09 37.7 53.6 0.00016 21.9 7.4 7.4 5 1 2 7 7 7 4 Pvs28 EGF domain cEGF PF12662.7 PFH33695.1 - 1.6e-07 31.2 44.8 0.0022 17.9 0.7 7.0 7 0 0 7 7 7 3 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PFH33695.1 - 7.6e-06 26.1 75.9 0.00025 21.3 8.3 6.2 6 0 0 6 6 6 5 Coagulation Factor Xa inhibitory site hEGF PF12661.7 PFH33695.1 - 2.2e-05 24.9 53.7 0.019 15.6 3.2 7.7 7 1 0 7 7 7 4 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 PFH33695.1 - 3.9e-05 23.6 19.3 7.2e-05 22.7 5.8 6.4 6 1 0 6 6 6 3 MSP1 EGF domain 1 Gram_pos_anchor PF00746.21 PFH33695.1 - 0.02 14.8 0.2 0.032 14.2 0.2 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Phage_int_SAM_1 PF02899.17 PFH33696.1 - 0.12 12.7 0.7 0.81 10.0 0.2 2.4 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF3141 PF11339.8 PFH33696.1 - 0.13 10.7 0.5 0.17 10.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Acyl-CoA_dh_M PF02770.19 PFH33699.1 - 1.3e-12 47.7 0.0 2.7e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 PFH33699.1 - 0.00039 20.0 0.0 0.00097 18.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 PFH33699.1 - 0.12 12.6 2.8 0.47 10.6 0.1 2.9 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 PFH33701.1 - 2.7e-10 40.6 0.7 4.7e-09 36.6 0.0 2.6 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain Mg_trans_NIPA PF05653.14 PFH33702.1 - 2.5e-11 43.3 9.0 5.1e-08 32.4 0.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 PFH33702.1 - 7.3e-09 35.9 1.8 7.3e-09 35.9 1.8 3.0 3 0 0 3 3 3 1 EamA-like transporter family dCMP_cyt_deam_1 PF00383.23 PFH33703.1 - 0.017 15.0 0.0 0.067 13.1 0.0 2.0 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region SAG PF04092.13 PFH33704.1 - 2.2e-16 60.8 18.7 7.1e-08 33.3 3.5 2.8 2 1 0 2 2 2 2 SRS domain SAG PF04092.13 PFH33705.1 - 4e-18 66.5 11.0 5.5e-09 36.9 0.3 2.5 2 1 0 2 2 2 2 SRS domain SAG PF04092.13 PFH33706.1 - 8.4e-20 71.9 12.3 5.7e-11 43.3 0.7 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH33707.1 - 4.1e-17 63.2 13.8 2.5e-08 34.7 1.5 2.6 2 1 0 2 2 2 2 SRS domain SAG PF04092.13 PFH33708.1 - 2.8e-19 70.2 10.1 6.6e-10 39.9 0.1 2.3 2 1 0 2 2 2 2 SRS domain SAG PF04092.13 PFH33709.1 - 3e-19 70.1 15.4 6.2e-11 43.2 0.9 2.5 1 1 1 2 2 2 2 SRS domain SAG PF04092.13 PFH33710.1 - 3.6e-16 60.1 8.7 1.4e-07 32.4 8.6 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH33711.1 - 4e-14 53.5 14.3 6.4e-08 33.4 6.7 2.9 2 1 0 2 2 2 2 SRS domain Snf7 PF03357.21 PFH33712.1 - 5.4e-08 32.6 1.2 7e-08 32.3 1.2 1.1 1 0 0 1 1 1 1 Snf7 DUF2712 PF10916.8 PFH33712.1 - 0.00073 20.2 0.0 0.0011 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2712) Ist1 PF03398.14 PFH33712.1 - 0.0071 16.3 0.6 0.016 15.1 0.6 1.6 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway INCENP_ARK-bind PF03941.15 PFH33713.1 - 4.8e-07 29.6 0.0 1.2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region SAG PF04092.13 PFH33714.1 - 1e-06 29.6 5.8 1.5e-06 29.0 5.8 1.2 1 0 0 1 1 1 1 SRS domain Fasciclin PF02469.22 PFH33716.1 - 1.3e-09 38.4 0.0 2.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain Citrate_bind PF16114.5 PFH33717.1 - 3.6e-86 287.2 0.0 5.9e-86 286.5 0.0 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 PFH33717.1 - 1e-21 77.5 0.0 1.1e-20 74.1 0.0 2.5 1 1 1 2 2 2 1 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 PFH33717.1 - 6.1e-11 42.4 0.1 2e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 CoA-ligase CoA_binding PF02629.19 PFH33717.1 - 4.8e-10 40.0 0.0 1.2e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 PFH33717.1 - 3.5e-07 30.0 0.0 3.9e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.6 PFH33717.1 - 0.0037 17.0 0.1 0.079 12.8 0.0 2.5 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Josephin PF02099.17 PFH33718.1 - 5.4e-13 49.4 0.0 7.2e-05 22.9 0.0 3.6 3 1 0 3 3 3 3 Josephin MMR1 PF08505.10 PFH33719.1 - 0.68 10.2 8.2 1 9.6 8.2 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein RRM_1 PF00076.22 PFH33720.1 - 4.5e-13 48.8 0.0 9.4e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 PFH33720.1 - 0.00065 19.5 0.1 0.016 15.0 0.1 2.4 1 1 1 2 2 2 2 Rrp7 RRM-like N-terminal domain CLTH PF10607.9 PFH33722.1 - 2e-10 40.7 0.0 7.9e-10 38.8 0.0 1.9 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Acyltransferase PF01553.21 PFH33725.1 - 4.9e-19 68.3 0.0 8.6e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4248 PF14053.6 PFH33726.1 - 0.052 13.6 0.0 0.37 10.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) DUF5339 PF17274.2 PFH33726.1 - 0.068 14.0 0.2 0.27 12.1 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5339) VPDSG-CTERM PF18205.1 PFH33726.1 - 0.15 11.9 0.3 0.41 10.5 0.3 1.8 1 0 0 1 1 1 0 VPDSG-CTERM motif RRM_1 PF00076.22 PFH33727.1 - 1.3e-20 73.0 0.2 3.4e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PFH33727.1 - 1.6e-08 34.2 0.0 0.0055 16.3 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PFH33727.1 - 2.9e-08 33.4 0.0 0.00015 21.6 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Calcipressin PF04847.12 PFH33727.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.5 2 0 0 2 2 2 0 Calcipressin RRM_3 PF08777.11 PFH33727.1 - 0.059 13.4 0.1 9.4 6.3 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Antistasin PF02822.14 PFH33728.1 - 0.48 11.1 3.2 0.77 10.5 3.2 1.3 1 0 0 1 1 1 0 Antistasin family Borrelia_P83 PF05262.11 PFH33728.1 - 9.6 4.6 51.1 13 4.2 51.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TT_ORF2 PF02957.15 PFH33729.1 - 5.3 8.0 7.0 21 6.1 7.0 2.2 1 0 0 1 1 1 0 TT viral ORF2 VWA_2 PF13519.6 PFH33730.1 - 1.8e-16 60.7 0.0 5.6e-16 59.1 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain GTP_EFTU PF00009.27 PFH33731.1 - 9.4e-60 201.5 0.0 1.4e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 PFH33731.1 - 2.5e-42 143.5 0.0 4.5e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 PFH33731.1 - 5.6e-30 103.3 0.0 1.1e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 PFH33731.1 - 4e-20 71.6 0.1 2.8e-17 62.5 0.1 2.6 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PFH33731.1 - 3e-11 43.6 0.0 7.2e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 PFH33731.1 - 3.6e-05 23.6 0.0 6.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Ribosomal_L12_N PF16320.5 PFH33731.1 - 0.49 10.1 3.2 2.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain AMPK1_CBM PF16561.5 PFH33732.1 - 1.5e-08 34.7 0.0 8.6e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Glycogen recognition site of AMP-activated protein kinase PP2C PF00481.21 PFH33732.1 - 1.7e-06 27.9 0.0 0.024 14.3 0.0 2.7 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 PFH33732.1 - 1.3e-05 25.2 0.0 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) RGS PF00615.19 PFH33733.1 - 0.21 11.9 0.1 0.61 10.4 0.0 1.7 2 0 0 2 2 2 0 Regulator of G protein signaling domain DUF4381 PF14316.6 PFH33734.1 - 0.026 14.7 0.2 0.066 13.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4229 PF14012.6 PFH33734.1 - 0.13 12.4 0.5 0.27 11.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF4748 PF15932.5 PFH33735.1 - 0.0031 17.2 0.1 0.0053 16.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) DUF4211 PF13926.6 PFH33736.1 - 1.8 8.6 5.6 14 5.7 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4211) Adeno_terminal PF02459.15 PFH33736.1 - 1.8 6.8 3.5 3.4 5.9 3.5 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein IQ PF00612.27 PFH33737.1 - 0.0022 17.6 0.1 0.0098 15.6 0.1 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif ArsA_ATPase PF02374.15 PFH33737.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase ACDC PF14733.6 PFH33739.1 - 3.5e-07 30.4 0.0 6.5e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.20 PFH33739.1 - 2.4e-06 27.7 4.8 0.0044 17.2 3.9 2.5 2 0 0 2 2 2 2 AP2 domain Thioredoxin PF00085.20 PFH33740.1 - 4.1e-39 132.7 0.0 3.6e-23 81.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 PFH33740.1 - 6.5e-10 39.2 0.0 1.4e-07 31.6 0.0 3.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 PFH33740.1 - 1.1e-05 25.8 0.2 0.015 15.7 0.0 3.6 2 2 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 PFH33740.1 - 0.00023 21.1 0.0 0.43 10.5 0.0 2.8 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 PFH33740.1 - 0.0013 18.8 0.1 0.33 11.2 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin-like OST3_OST6 PF04756.13 PFH33740.1 - 0.048 13.0 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PFH33740.1 - 0.17 12.2 0.0 15 6.0 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin-like Kazal_2 PF07648.15 PFH33742.1 - 1.1e-18 67.0 14.3 1.1e-08 35.0 4.4 3.4 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PFH33742.1 - 8.8e-14 51.3 9.8 1.3e-06 28.3 0.1 3.1 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain ECH_2 PF16113.5 PFH33743.1 - 8.9e-96 321.3 0.0 1.9e-95 320.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 PFH33743.1 - 4e-29 101.7 0.0 5.8e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Proteasom_Rpn13 PF04683.13 PFH33744.1 - 6.6e-26 90.7 0.0 1e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 PFH33744.1 - 9.5e-20 70.9 0.5 1.5e-19 70.2 0.5 1.3 1 0 0 1 1 1 1 UCH-binding domain ORC_WH_C PF18137.1 PFH33744.1 - 4.4 7.4 6.6 8.3 6.5 6.6 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal RRM_1 PF00076.22 PFH33745.1 - 0.00011 22.0 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 PFH33745.1 - 0.00011 22.0 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 RL domain BioT2 PF15368.6 PFH33745.1 - 0.04 13.9 0.3 0.059 13.3 0.3 1.2 1 0 0 1 1 1 0 Spermatogenesis family BioT2 COG6 PF06419.11 PFH33747.1 - 2.5e-30 105.3 0.0 1.3e-11 43.5 0.0 3.8 4 1 0 4 4 4 3 Conserved oligomeric complex COG6 SAG PF04092.13 PFH33749.1 - 1e-09 39.3 1.0 0.0025 18.6 0.1 2.7 2 1 0 2 2 2 2 SRS domain TPR_19 PF14559.6 PFH33749.1 - 0.093 13.3 0.0 7.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SAG PF04092.13 PFH33750.1 - 3.1e-06 28.0 0.9 0.013 16.3 0.9 3.1 3 0 0 3 3 3 2 SRS domain BTB PF00651.31 PFH33751.1 - 6e-12 45.8 0.3 0.014 15.6 0.0 3.6 4 0 0 4 4 4 3 BTB/POZ domain BTB PF00651.31 PFH33752.1 - 0.0083 16.3 2.1 0.056 13.7 0.1 2.5 2 1 1 3 3 3 1 BTB/POZ domain PhoLip_ATPase_C PF16212.5 PFH33753.1 - 2.9e-47 161.5 25.0 2.9e-47 161.5 25.0 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 PFH33753.1 - 3.2e-14 53.7 1.9 2.1e-08 34.7 0.5 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 PFH33753.1 - 3.7e-14 52.2 6.3 3.7e-14 52.2 6.3 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 PFH33753.1 - 4.7e-09 36.2 0.0 5.1e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 PFH33753.1 - 1.1e-05 25.0 12.0 0.0015 18.0 0.0 3.4 4 0 0 4 4 4 2 E1-E2 ATPase Hydrolase_3 PF08282.12 PFH33753.1 - 0.016 14.9 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1772 PF08592.11 PFH33753.1 - 0.027 14.8 0.1 0.027 14.8 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) PseudoU_synth_1 PF01416.20 PFH33754.1 - 1.8e-16 60.5 0.0 6.7e-15 55.5 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF1084 PF06454.11 PFH33755.1 - 1.4e-11 44.3 2.3 3e-11 43.2 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF1129 PF06570.11 PFH33755.1 - 0.00032 20.2 0.1 0.0007 19.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) 7tm_3 PF00003.22 PFH33755.1 - 0.51 10.0 10.6 0.19 11.4 6.9 2.1 2 1 1 3 3 3 0 7 transmembrane sweet-taste receptor of 3 GCPR LSM PF01423.22 PFH33757.1 - 7.7e-13 47.9 0.2 1.1e-12 47.4 0.2 1.3 1 0 0 1 1 1 1 LSM domain Spec3 PF15795.5 PFH33760.1 - 0.00061 20.3 8.1 0.00061 20.3 8.1 2.1 1 1 1 2 2 2 1 Ectodermal ciliogenesis protein DUF4914 PF16260.5 PFH33760.1 - 0.11 10.5 4.0 1.1 7.3 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4914) DUF3040 PF11239.8 PFH33760.1 - 0.21 11.9 4.7 0.81 10.0 4.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) FHA PF00498.26 PFH33761.1 - 0.00049 20.4 0.1 0.016 15.6 0.0 2.6 2 1 0 2 2 2 1 FHA domain Spec3 PF15795.5 PFH33763.1 - 5.8e-05 23.6 7.3 5.8e-05 23.6 7.3 2.1 1 1 1 2 2 2 2 Ectodermal ciliogenesis protein DUF998 PF06197.13 PFH33763.1 - 1.7 8.2 11.2 0.26 10.9 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Phage_holin_3_6 PF07332.11 PFH33763.1 - 3.4 7.8 8.6 4.5 7.4 8.6 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MMS19_N PF14500.6 PFH33764.1 - 3.2e-37 128.5 0.0 1.9e-36 126.0 0.0 2.1 1 1 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II BAGE PF08180.11 PFH33765.1 - 0.32 11.1 1.9 0.67 10.1 1.9 1.5 1 0 0 1 1 1 0 B melanoma antigen family IMCp PF12314.8 PFH33765.1 - 0.78 10.1 8.3 0.2 11.9 4.7 1.9 2 0 0 2 2 2 0 Inner membrane complex protein Band_7 PF01145.25 PFH33766.1 - 1.2e-28 100.3 0.3 2e-28 99.6 0.3 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 PFH33766.1 - 3e-22 78.4 0.3 8.4e-22 77.0 0.3 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 PFH33766.1 - 0.014 15.1 0.0 0.037 13.8 0.0 1.7 2 0 0 2 2 2 0 SPFH domain-Band 7 family META PF03724.16 PFH33766.1 - 0.02 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 META domain LMBR1 PF04791.16 PFH33767.1 - 1.8e-57 195.4 19.5 1.2e-33 116.9 2.5 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF384 PF04064.13 PFH33768.1 - 1.1e-11 44.4 3.2 1.6e-11 43.9 1.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF383 PF04063.14 PFH33768.1 - 2.3e-05 24.2 0.0 6.5e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF383) HEAT_2 PF13646.6 PFH33768.1 - 0.027 14.8 1.3 2.2 8.7 0.0 3.2 3 0 0 3 3 3 0 HEAT repeats DUF4407 PF14362.6 PFH33770.1 - 5.8 6.2 9.2 6.3 6.1 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Aldedh PF00171.22 PFH33772.1 - 1.5e-173 577.6 0.0 1.7e-173 577.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 PFH33772.1 - 1.6e-05 24.4 0.0 0.00011 21.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) DEAD PF00270.29 PFH33774.1 - 2.4e-39 134.9 0.0 3.8e-35 121.2 0.0 3.2 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH33774.1 - 1.4e-28 99.4 0.0 1e-27 96.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 PFH33774.1 - 9.8e-07 29.0 0.0 2.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 GUCT (NUC152) domain UTP25 PF06862.12 PFH33774.1 - 0.001 17.9 0.0 0.88 8.3 0.0 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 UL21a PF17636.2 PFH33774.1 - 0.027 14.5 0.0 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 Viral Unique Long protein 21a RNHCP PF12647.7 PFH33775.1 - 0.004 17.1 1.9 1.9 8.5 0.0 3.2 3 0 0 3 3 3 1 RNHCP domain Yippee-Mis18 PF03226.14 PFH33775.1 - 0.023 14.9 0.1 0.037 14.2 0.1 1.4 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Nudix_N_2 PF14803.6 PFH33775.1 - 0.024 14.5 4.5 3 7.8 0.1 3.3 3 0 0 3 3 3 0 Nudix N-terminal zf_UBZ PF18439.1 PFH33775.1 - 0.052 13.2 0.4 8.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 PFH33775.1 - 0.31 11.1 3.0 1.4 9.0 0.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon DNA_RNApol_7kD PF03604.13 PFH33775.1 - 1.2 8.8 8.4 14 5.5 0.1 3.5 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit FYVE PF01363.21 PFH33775.1 - 5.5 7.2 12.3 17 5.6 5.2 2.8 1 1 1 2 2 2 0 FYVE zinc finger PseudoU_synth_2 PF00849.22 PFH33776.1 - 1.9e-05 24.8 0.0 0.00094 19.3 0.0 2.4 2 0 0 2 2 2 2 RNA pseudouridylate synthase PUB PF09409.10 PFH33777.1 - 4e-22 78.0 0.0 1.5e-21 76.1 0.0 2.0 2 0 0 2 2 2 1 PUB domain UBA PF00627.31 PFH33777.1 - 0.054 13.4 0.5 0.65 10.0 0.5 2.4 1 1 0 1 1 1 0 UBA/TS-N domain AAA_23 PF13476.6 PFH33777.1 - 0.62 10.5 13.8 1 9.8 13.8 1.5 1 0 0 1 1 1 0 AAA domain MCM3AP_GANP PF16769.5 PFH33777.1 - 1 7.5 13.7 1.5 6.9 13.7 1.3 1 0 0 1 1 1 0 MCM3AP domain of GANP Exonuc_VII_L PF02601.15 PFH33777.1 - 2.4 7.6 10.9 3 7.3 10.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TERB2 PF15101.6 PFH33777.1 - 3.5 7.6 7.7 5.6 7.0 7.7 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CwsA PF10814.8 PFH33777.1 - 4 7.6 5.0 8 6.6 5.0 1.5 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Atg14 PF10186.9 PFH33777.1 - 9.9 5.1 15.0 16 4.5 15.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rab5ip PF07019.12 PFH33779.1 - 1.9e-10 41.2 11.1 2.5e-10 40.8 11.1 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) FA_desaturase PF00487.24 PFH33779.1 - 0.025 14.4 3.5 0.028 14.2 3.5 1.1 1 0 0 1 1 1 0 Fatty acid desaturase TPR_21 PF09976.9 PFH33779.1 - 1.5 8.5 6.3 2.2 7.9 6.3 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain GTP_EFTU PF00009.27 PFH33780.1 - 1.6e-35 122.5 0.0 2.3e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PFH33780.1 - 2.1e-06 27.8 0.0 0.076 13.1 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 PFH33780.1 - 3.9e-06 27.1 0.2 1.3e-05 25.5 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain SRPRB PF09439.10 PFH33780.1 - 0.078 12.4 0.0 6.5 6.1 0.0 2.2 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PFH33780.1 - 0.28 11.1 1.1 4.5 7.2 0.6 2.5 1 1 1 2 2 2 0 RsgA GTPase Mog1 PF04603.12 PFH33783.1 - 1.5e-35 122.5 0.1 2.1e-35 122.1 0.1 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Haemadin PF09065.10 PFH33783.1 - 0.077 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Haemadin DOT1 PF08123.13 PFH33784.1 - 0.0024 17.4 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 PGK PF00162.19 PFH33785.1 - 1.5e-149 498.1 0.0 1.8e-149 497.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.11 PFH33785.1 - 0.04 13.5 0.5 0.35 10.4 0.0 2.5 2 1 1 3 3 3 0 Propionate catabolism activator NIF PF03031.18 PFH33787.1 - 1.9e-25 89.4 0.0 3.3e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Brix PF04427.18 PFH33788.1 - 2e-32 112.9 0.8 2.4e-32 112.6 0.1 1.5 2 0 0 2 2 2 1 Brix domain WW PF00397.26 PFH33790.1 - 2.4e-07 30.7 0.3 5e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 WW domain zf-U1 PF06220.12 PFH33790.1 - 2.3e-05 24.1 0.5 4.2e-05 23.2 0.5 1.5 1 0 0 1 1 1 1 U1 zinc finger Zn_ribbon_2 PF12674.7 PFH33790.1 - 0.14 12.8 1.2 0.26 12.0 1.2 1.4 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-DBF PF07535.12 PFH33790.1 - 0.4 10.8 2.0 0.8 9.9 2.0 1.5 1 1 0 1 1 1 0 DBF zinc finger DUF2423 PF10338.9 PFH33791.1 - 3.5e-11 43.2 2.2 7.2e-11 42.1 1.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) DUF3449 PF11931.8 PFH33792.1 - 4.3e-76 254.8 1.8 4.3e-76 254.8 1.8 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 PFH33792.1 - 3.6e-17 62.6 1.5 3.6e-17 62.6 1.5 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 PFH33792.1 - 8.3e-07 28.8 0.1 3.4e-06 26.8 0.1 2.1 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain BUD22 PF09073.10 PFH33792.1 - 0.0014 18.1 5.4 0.0022 17.4 5.4 1.3 1 0 0 1 1 1 1 BUD22 zf-met PF12874.7 PFH33792.1 - 0.014 15.7 0.7 3.6 8.1 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Chlorosome_CsmC PF11098.8 PFH33792.1 - 0.094 12.7 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Chlorosome envelope protein C Desulfoferrod_N PF06397.12 PFH33792.1 - 0.16 11.6 0.2 0.28 10.8 0.2 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Acyl-CoA_dh_2 PF08028.11 PFH33792.1 - 3.5 7.9 7.5 0.85 9.9 2.8 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Adaptin_N PF01602.20 PFH33793.1 - 9.5e-54 182.8 0.0 3.5e-51 174.3 0.0 3.2 1 1 0 1 1 1 1 Adaptin N terminal region NifU PF01106.17 PFH33795.1 - 1.2e-23 83.1 0.0 2.9e-19 69.0 0.0 2.4 2 0 0 2 2 2 2 NifU-like domain Methyltransf_11 PF08241.12 PFH33796.1 - 5.4e-10 39.8 0.0 2.4e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH33796.1 - 3.3e-07 30.9 0.0 2.4e-05 24.9 0.0 3.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH33796.1 - 2.5e-06 28.2 0.0 5.4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 PFH33796.1 - 3.1e-05 23.7 0.0 6.5e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 PFH33796.1 - 8e-05 22.5 0.0 0.00035 20.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PFH33796.1 - 0.00028 20.7 0.0 0.0014 18.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain zf-A20 PF01754.16 PFH33797.1 - 2.1e-11 43.5 9.3 2.1e-11 43.5 9.3 2.1 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 PFH33797.1 - 1.4e-09 37.9 7.4 1.4e-09 37.9 7.4 1.8 2 0 0 2 2 2 1 AN1-like Zinc finger DUF4428 PF14471.6 PFH33797.1 - 0.078 12.9 3.0 7 6.7 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Hamartin PF04388.12 PFH33797.1 - 0.12 11.0 2.4 0.13 10.9 2.4 1.1 1 0 0 1 1 1 0 Hamartin protein SOG2 PF10428.9 PFH33797.1 - 5.1 6.2 9.9 6.1 5.9 9.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein WD40 PF00400.32 PFH33799.1 - 8.5e-16 58.1 14.4 0.0042 17.9 0.0 9.9 11 0 0 11 11 11 6 WD domain, G-beta repeat Band_7 PF01145.25 PFH33802.1 - 2.8e-05 24.2 0.1 3.3e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Peptidase_S8 PF00082.22 PFH33803.1 - 1.9e-45 155.4 0.3 1.9e-45 155.4 0.3 2.5 3 1 1 4 4 4 1 Subtilase family PAN_2 PF08276.11 PFH33803.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 PAN-like domain RabGAP-TBC PF00566.18 PFH33804.1 - 5.5e-39 134.0 6.3 8.9e-39 133.4 3.9 2.4 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF846 PF05832.12 PFH33806.1 - 2.9e-44 150.5 11.1 3.6e-44 150.2 11.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) FAD_oxidored PF12831.7 PFH33806.1 - 0.14 11.5 0.9 0.2 11.0 0.9 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF2101 PF09874.9 PFH33806.1 - 0.2 11.3 0.4 0.57 9.9 0.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) CDC48_2 PF02933.17 PFH33808.1 - 0.12 12.1 0.1 3.1 7.6 0.0 2.4 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 SPT16 PF08644.11 PFH33812.1 - 3.6e-46 157.1 0.0 3.6e-46 157.1 0.0 3.5 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 PFH33812.1 - 2.3e-22 79.7 0.0 3.9e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 FACT-Spt16_Nlob PF14826.6 PFH33812.1 - 8.1e-19 68.0 0.3 3.6e-18 65.9 0.0 2.3 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.12 PFH33812.1 - 9.6e-14 51.6 0.0 3.3e-13 49.8 0.0 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DEAD PF00270.29 PFH33814.1 - 1.9e-41 141.8 0.0 3.9e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH33814.1 - 5.4e-26 91.1 0.0 1.4e-25 89.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Corona_NS1 PF06145.11 PFH33814.1 - 6.6 6.4 6.1 0.33 10.5 0.6 1.7 2 0 0 2 2 2 0 Coronavirus nonstructural protein NS1 DUF456 PF04306.13 PFH33815.1 - 0.017 15.4 3.4 0.04 14.2 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF1269 PF06897.12 PFH33815.1 - 0.19 12.1 4.1 0.35 11.2 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) CLZ PF16526.5 PFH33816.1 - 0.033 14.5 4.2 0.3 11.5 0.9 2.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GREB1 PF15782.5 PFH33816.1 - 7.8 3.5 8.9 14 2.6 8.9 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Tubulin PF00091.25 PFH33817.1 - 2.6e-69 233.4 0.0 5e-69 232.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PFH33817.1 - 2.4e-42 144.1 0.1 3.6e-42 143.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PFH33817.1 - 9e-05 22.8 0.0 0.00023 21.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 PFH33817.1 - 0.0059 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 PFH33817.1 - 0.0088 15.3 0.0 0.019 14.1 0.0 1.5 2 0 0 2 2 2 1 Tubulin like UCH PF00443.29 PFH33818.1 - 1e-24 87.5 0.0 9.1e-24 84.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PFH33818.1 - 0.036 13.6 0.0 9 5.8 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase RsfS PF02410.15 PFH33819.1 - 4.2e-17 62.4 0.1 9.3e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation DSPc PF00782.20 PFH33820.1 - 5.8e-21 74.7 0.0 7.9e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PFH33820.1 - 0.0014 18.2 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 PFH33820.1 - 0.016 14.9 0.1 0.025 14.2 0.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) FtsJ PF01728.19 PFH33821.1 - 8e-16 58.7 0.0 6.6e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 FtsJ-like methyltransferase RRM_1 PF00076.22 PFH33822.1 - 9.7e-05 22.1 0.0 0.033 14.0 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_UL25 PF01499.16 PFH33822.1 - 0.068 11.7 1.5 0.094 11.2 1.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DNA_pol3_tau_5 PF12170.8 PFH33822.1 - 0.078 13.0 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha Atg14 PF10186.9 PFH33822.1 - 1.5 7.8 5.7 2.3 7.2 5.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4746 PF15928.5 PFH33822.1 - 5.1 6.4 6.8 7.4 5.9 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pkinase PF00069.25 PFH33824.1 - 2.5e-11 43.5 0.0 0.0014 18.1 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH33824.1 - 0.00037 19.9 0.0 1.4 8.1 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Adap_comp_sub PF00928.21 PFH33826.1 - 4.8e-08 32.7 0.0 7e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 PFH33826.1 - 0.033 14.1 0.3 0.061 13.3 0.3 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Rrn6 PF10214.9 PFH33826.1 - 0.07 11.6 4.0 0.094 11.2 4.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4202 PF13875.6 PFH33826.1 - 0.97 9.3 3.1 0.44 10.4 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4202) DSPc PF00782.20 PFH33828.1 - 3.4e-21 75.5 0.0 6.8e-21 74.5 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PFH33828.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 PFH33828.1 - 0.17 12.2 0.0 0.35 11.2 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Pre-PUA PF17832.1 PFH33829.1 - 1e-26 93.4 0.1 1.6e-26 92.8 0.1 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 PFH33829.1 - 2.6e-15 56.1 0.0 4e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 PUA domain DUF5336 PF17270.2 PFH33830.1 - 0.052 13.2 0.2 0.052 13.2 0.2 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5336) Mid2 PF04478.12 PFH33830.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Cwf_Cwc_15 PF04889.12 PFH33830.1 - 0.16 11.6 4.8 0.27 10.9 4.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Amnionless PF14828.6 PFH33830.1 - 0.22 10.3 0.1 0.26 10.1 0.1 1.1 1 0 0 1 1 1 0 Amnionless His_Phos_1 PF00300.22 PFH33832.1 - 2.5e-12 46.9 0.0 0.0021 17.8 0.0 3.9 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) Thionin PF00321.17 PFH33832.1 - 0.1 13.1 0.3 0.21 12.1 0.3 1.5 1 0 0 1 1 1 0 Plant thionin ThiS PF02597.20 PFH33833.1 - 1.6e-07 31.8 0.0 1e-06 29.2 0.0 2.0 2 0 0 2 2 2 1 ThiS family SPRY PF00622.28 PFH33834.1 - 2.1e-12 47.2 0.0 9.8e-07 28.9 0.0 2.6 2 1 0 2 2 2 2 SPRY domain Sdh5 PF03937.16 PFH33837.1 - 0.0026 17.7 1.4 0.0057 16.6 1.4 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Kinesin PF00225.23 PFH33838.1 - 2e-105 352.4 0.0 4.6e-105 351.2 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PFH33838.1 - 4.3e-23 81.9 0.0 1.3e-21 77.1 0.0 2.9 2 0 0 2 2 2 1 Microtubule binding KIF1B PF12423.8 PFH33838.1 - 4.7e-06 26.9 0.1 4.7e-06 26.9 0.1 2.7 3 0 0 3 3 3 1 Kinesin protein 1B Kinesin_assoc PF16183.5 PFH33838.1 - 1.1e-05 25.7 0.9 1.1e-05 25.7 0.9 3.2 2 1 1 3 3 3 1 Kinesin-associated OmpH PF03938.14 PFH33838.1 - 0.0017 18.7 28.3 0.066 13.6 3.7 2.5 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) FHA PF00498.26 PFH33838.1 - 0.0087 16.4 0.0 0.022 15.1 0.0 1.8 1 0 0 1 1 1 1 FHA domain DUF2064 PF09837.9 PFH33838.1 - 0.014 15.2 1.4 0.046 13.5 1.4 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) S4_2 PF13275.6 PFH33838.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 S4 domain FAM184 PF15665.5 PFH33838.1 - 0.45 10.3 28.6 0.04 13.7 3.7 2.4 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF4228 PF14009.6 PFH33838.1 - 0.54 10.6 11.2 0.11 12.9 4.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) FAM76 PF16046.5 PFH33838.1 - 3.7 6.8 14.7 0.13 11.6 1.3 2.2 2 0 0 2 2 2 0 FAM76 protein Allexi_40kDa PF05549.11 PFH33838.1 - 9.8 5.6 7.9 2.3 7.7 1.1 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein Actin PF00022.19 PFH33839.1 - 3.2e-34 118.2 0.0 7.7e-34 117.0 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 PFH33839.1 - 0.003 16.4 0.0 0.005 15.7 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein CCDC144C PF14915.6 PFH33841.1 - 1.9e-05 23.9 11.9 4.4e-05 22.8 1.3 3.3 3 0 0 3 3 3 2 CCDC144C protein coiled-coil region Cep57_CLD_2 PF14197.6 PFH33841.1 - 0.00048 20.2 15.9 0.35 11.0 0.1 3.7 2 1 1 3 3 3 2 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.9 PFH33841.1 - 0.0011 19.0 4.0 0.0011 19.0 4.0 3.9 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MSP PF01716.18 PFH33841.1 - 0.016 14.4 1.5 6.1 6.0 0.0 3.1 3 0 0 3 3 3 0 Manganese-stabilising protein / photosystem II polypeptide TSC22 PF01166.18 PFH33841.1 - 0.029 14.7 5.2 0.53 10.6 0.0 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4296 PF14129.6 PFH33841.1 - 0.11 13.1 0.1 0.26 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) ZapB PF06005.12 PFH33841.1 - 0.12 12.8 0.1 0.12 12.8 0.1 4.5 4 1 0 4 4 3 0 Cell division protein ZapB Mto2_bdg PF12808.7 PFH33841.1 - 0.3 11.4 14.1 0.02 15.2 7.3 2.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FlaC_arch PF05377.11 PFH33841.1 - 0.98 9.9 4.9 1.7 9.1 0.6 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 PFH33841.1 - 1 8.2 17.0 0.35 9.7 4.3 2.6 2 0 0 2 2 2 0 Spc7 kinetochore protein KELK PF15796.5 PFH33841.1 - 6.7 7.3 21.1 16 6.0 5.1 4.6 3 1 1 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Alba PF01918.21 PFH33842.1 - 1.1e-19 70.0 0.7 1.6e-19 69.5 0.7 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 PFH33842.1 - 0.0019 18.1 0.1 0.0024 17.8 0.1 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P APG6 PF04111.12 PFH33844.1 - 4.9e-44 150.4 0.0 7.1e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 PFH33844.1 - 5.5 7.5 26.7 87 3.7 26.7 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region Ctr PF04145.15 PFH33845.1 - 4.1e-18 66.4 0.0 1.3e-17 64.7 0.0 1.7 1 1 0 1 1 1 1 Ctr copper transporter family CRAL_TRIO PF00650.20 PFH33846.1 - 3.3e-08 33.4 0.0 4.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain DNA_topoisoIV PF00521.20 PFH33847.1 - 1.2e-129 433.0 0.1 1.5e-87 294.2 0.0 2.2 1 1 1 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 PFH33847.1 - 1.8e-27 94.6 17.3 3.9e-10 39.0 0.2 6.8 7 0 0 7 7 7 6 DNA gyrase C-terminal domain, beta-propeller Sporozoite_P67 PF05642.11 PFH33847.1 - 0.0012 17.0 13.4 0.0012 17.0 13.4 3.3 3 0 0 3 3 3 1 Sporozoite P67 surface antigen DUF2835 PF11197.8 PFH33847.1 - 0.13 12.1 0.1 0.42 10.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) Rab_eff_C PF04698.12 PFH33848.1 - 0.27 9.5 4.0 0.34 9.1 4.0 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus Carboxyl_trans PF01039.22 PFH33849.1 - 9.7e-158 525.8 0.0 1.9e-157 524.9 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 PFH33849.1 - 9.2e-51 172.3 0.0 1.6e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ACC_central PF08326.12 PFH33849.1 - 7.9e-36 123.6 0.0 5.2e-33 114.3 0.0 3.2 2 1 0 2 2 2 1 Acetyl-CoA carboxylase, central region Biotin_carb_N PF00289.22 PFH33849.1 - 2.5e-30 105.3 0.0 4.8e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PFH33849.1 - 2e-21 76.1 0.0 1.2e-20 73.6 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 PFH33849.1 - 1.2e-11 44.3 0.1 2.9e-11 43.0 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 PFH33849.1 - 5.8e-09 35.8 0.0 1.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 PFH33849.1 - 1.8e-08 34.2 0.1 4.5e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 PFH33849.1 - 4.7e-06 26.7 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain DUF3458_C PF17432.2 PFH33850.1 - 3.3e-85 286.3 4.6 4.9e-85 285.7 4.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 PFH33850.1 - 9e-46 156.2 0.0 1.4e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 PFH33850.1 - 6e-15 55.5 0.0 1.4e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 PFH33850.1 - 1.1e-08 35.5 0.0 2.2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 PFH33850.1 - 0.082 13.3 0.4 0.54 10.7 0.4 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase ICL PF00463.21 PFH33850.1 - 0.11 11.0 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 Isocitrate lyase family 2OG-FeII_Oxy_3 PF13640.6 PFH33853.1 - 6.6e-12 46.2 0.0 1.9e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DAHP_synth_2 PF01474.16 PFH33855.1 - 4.1e-163 543.0 0.0 6e-163 542.4 0.0 1.2 1 1 0 1 1 1 1 Class-II DAHP synthetase family DUF2267 PF10025.9 PFH33855.1 - 0.037 14.3 0.1 2.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) DUF3232 PF11554.8 PFH33856.1 - 0.25 11.7 0.9 0.4 11.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3232) Y_phosphatase3 PF13350.6 PFH33857.1 - 0.00075 19.5 0.0 0.0018 18.3 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 PFH33857.1 - 0.0016 18.3 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ASH PF15780.5 PFH33858.1 - 3.3e-15 56.1 5.1 0.0019 18.4 0.2 6.3 6 0 0 6 6 6 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 PFH33858.1 - 1.2e-05 25.4 0.4 0.63 10.2 0.1 3.7 3 0 0 3 3 3 3 Flagellar-associated PapD-like Pro_isomerase PF00160.21 PFH33859.1 - 3.4e-44 150.9 0.0 3.8e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SAG PF04092.13 PFH33860.1 - 3e-40 138.1 13.5 9.4e-22 78.2 2.2 2.0 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH33861.1 - 4.7e-46 156.8 18.9 2.3e-23 83.4 4.6 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH33862.1 - 8.2e-48 162.5 14.3 2.1e-24 86.8 4.6 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH33863.1 - 1.5e-47 161.6 11.6 4.5e-24 85.7 1.7 2.0 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH33864.1 - 3.5e-23 82.8 2.0 4.8e-23 82.4 2.0 1.2 1 0 0 1 1 1 1 SRS domain zf-CW PF07496.15 PFH33865.1 - 2.2e-28 98.0 25.0 1.7e-15 56.7 6.8 2.5 2 0 0 2 2 2 2 CW-type Zinc Finger PHD PF00628.29 PFH33865.1 - 0.036 14.0 6.1 0.5 10.3 2.1 2.7 2 0 0 2 2 2 0 PHD-finger NUDIX_2 PF13869.6 PFH33866.1 - 2.3e-50 170.8 0.0 3.9e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotide hydrolase CTK3_C PF12350.8 PFH33866.1 - 0.37 11.0 4.6 5.4 7.2 0.1 2.6 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus Peptidase_M48_N PF16491.5 PFH33868.1 - 1.5e-60 204.2 0.9 8.2e-60 201.8 0.0 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 PFH33868.1 - 2e-46 158.2 0.0 3.6e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 PFH33868.1 - 0.17 11.0 0.1 0.37 9.9 0.1 1.5 2 0 0 2 2 2 0 BlaR1 peptidase M56 Acetyltransf_10 PF13673.7 PFH33869.1 - 1.9e-10 40.8 0.0 3.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PFH33869.1 - 1.1e-09 38.5 0.1 2.3e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PFH33869.1 - 3.6e-09 36.9 0.0 6.6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PFH33869.1 - 3.8e-06 26.8 0.1 1e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PFH33869.1 - 1.9e-05 24.7 0.0 0.00022 21.3 0.0 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PFH33869.1 - 0.00036 20.6 0.1 0.0017 18.5 0.0 2.0 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase DUF2312 PF10073.9 PFH33869.1 - 0.0065 16.1 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2312) FtsJ PF01728.19 PFH33871.1 - 2.3e-53 180.9 0.0 3.1e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase NSP16 PF06460.12 PFH33871.1 - 0.24 10.5 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP16 Choline_transpo PF04515.12 PFH33872.1 - 7.9e-31 107.4 19.9 7.9e-31 107.4 19.9 3.4 3 1 0 3 3 3 1 Plasma-membrane choline transporter DUF2829 PF11195.8 PFH33873.1 - 0.82 10.0 3.8 13 6.1 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2829) UPF0561 PF10573.9 PFH33873.1 - 1.3 9.1 6.4 1.2 9.2 0.2 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0561 Telomere_reg-2 PF10193.9 PFH33874.1 - 1.5e-05 25.3 0.2 4.3e-05 23.9 0.2 1.8 1 0 0 1 1 1 1 Telomere length regulation protein HEAT PF02985.22 PFH33875.1 - 4.8e-10 38.8 21.5 0.00086 19.4 0.1 7.7 8 0 0 8 8 8 4 HEAT repeat Adaptin_N PF01602.20 PFH33875.1 - 0.58 8.6 2.8 14 4.1 0.2 2.9 3 1 0 3 3 3 0 Adaptin N terminal region HEAT_2 PF13646.6 PFH33875.1 - 0.87 10.0 24.1 0.33 11.4 1.1 6.1 4 1 2 6 6 6 0 HEAT repeats DUF2321 PF10083.9 PFH33876.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Dynactin_p22 PF07426.11 PFH33878.1 - 1.2e-12 48.0 4.0 1.7e-12 47.5 4.0 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Q_salvage PF10343.9 PFH33878.1 - 0.025 14.2 1.8 0.034 13.7 1.6 1.3 1 1 0 1 1 1 0 Potential Queuosine, Q, salvage protein family Snapin_Pallidin PF14712.6 PFH33878.1 - 0.032 14.6 0.8 0.032 14.6 0.8 2.1 2 0 0 2 2 2 0 Snapin/Pallidin SIN1_PH PF16979.5 PFH33878.1 - 0.035 14.4 0.1 0.14 12.5 0.0 1.9 2 1 1 3 3 3 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Sulfotransfer_3 PF13469.6 PFH33878.1 - 0.037 14.4 1.1 0.068 13.6 0.5 1.6 1 1 0 1 1 1 0 Sulfotransferase family DEAD PF00270.29 PFH33879.1 - 4.4e-30 104.7 0.1 1.2e-29 103.3 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH33879.1 - 6.6e-22 77.9 0.0 2.7e-21 76.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH33879.1 - 9.9e-07 28.9 0.0 2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PFH33879.1 - 0.037 14.3 0.0 0.15 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF3638 PF12340.8 PFH33879.1 - 0.097 12.0 0.0 0.4 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3638) DHQ_synthase PF01761.20 PFH33880.1 - 8.6e-69 231.6 0.0 5.5e-42 143.7 0.0 2.4 2 0 0 2 2 2 2 3-dehydroquinate synthase EPSP_synthase PF00275.20 PFH33880.1 - 3.5e-32 111.6 4.6 1.2e-07 30.8 0.0 8.6 8 1 0 8 8 8 5 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Shikimate_dh_N PF08501.11 PFH33880.1 - 2.7e-12 46.8 0.0 6.8e-09 35.9 0.0 2.6 2 0 0 2 2 2 2 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 PFH33880.1 - 3.1e-11 43.6 0.0 2.2e-05 24.6 0.0 4.0 4 0 0 4 4 4 2 Shikimate kinase DHquinase_I PF01487.15 PFH33880.1 - 1.7e-10 41.5 0.0 1.5e-07 31.9 0.1 2.6 2 0 0 2 2 2 2 Type I 3-dehydroquinase AAA_33 PF13671.6 PFH33880.1 - 0.0043 17.2 0.0 0.76 9.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain Fe-ADH PF00465.19 PFH33880.1 - 0.039 12.8 0.9 0.095 11.5 0.9 1.6 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase AAA_16 PF13191.6 PFH33880.1 - 0.042 14.2 0.1 0.22 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Fe-ADH_2 PF13685.6 PFH33880.1 - 0.19 11.4 3.0 0.18 11.4 0.2 2.2 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase VirionAssem_T7 PF11653.8 PFH33880.1 - 8.4 7.0 10.3 0.062 13.8 0.4 2.6 3 0 0 3 3 3 0 Bacteriophage T7 virion assembly protein Septin PF00735.18 PFH33881.1 - 5.1e-09 35.8 0.0 8.6e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Septin T2SSE PF00437.20 PFH33881.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2756 PF10956.8 PFH33881.1 - 0.13 12.8 1.9 0.36 11.3 1.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) G-alpha PF00503.20 PFH33881.1 - 0.16 11.1 1.1 0.21 10.7 0.1 1.6 2 0 0 2 2 2 0 G-protein alpha subunit FlxA PF14282.6 PFH33881.1 - 0.61 10.1 5.7 1.4 9.0 5.7 1.5 1 0 0 1 1 1 0 FlxA-like protein Snf7 PF03357.21 PFH33881.1 - 1.8 8.1 4.3 3.8 7.1 4.3 1.4 1 0 0 1 1 1 0 Snf7 ATP-grasp_2 PF08442.10 PFH33883.1 - 3.5e-61 206.3 0.1 7e-61 205.3 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 PFH33883.1 - 3.2e-20 72.5 0.4 6e-20 71.6 0.4 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 PFH33883.1 - 3e-06 26.9 0.5 0.0004 19.9 0.1 2.9 2 1 0 2 2 2 1 ATP-grasp domain OKR_DC_1_N PF03709.15 PFH33883.1 - 0.0022 18.2 0.1 0.0049 17.1 0.1 1.6 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain Succ_CoA_lig PF13607.6 PFH33883.1 - 0.21 11.4 0.1 0.21 11.4 0.1 1.9 3 0 0 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain LSM PF01423.22 PFH33884.1 - 2.7e-16 59.0 0.5 4.1e-16 58.4 0.5 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PFH33884.1 - 7.5e-06 26.0 0.1 1.1e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 PFH33884.1 - 0.079 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain Pyr_redox_2 PF07992.14 PFH33885.1 - 2.7e-55 187.7 0.9 3.5e-55 187.3 0.9 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PFH33885.1 - 4.4e-23 81.6 0.0 9.5e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PFH33885.1 - 2.4e-15 56.8 0.8 5.2e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PFH33885.1 - 1.9e-07 30.7 0.2 0.00022 20.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PFH33885.1 - 4.7e-06 25.9 6.9 0.00034 19.8 3.3 3.1 2 1 1 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 PFH33885.1 - 4.4e-05 22.8 0.2 0.0059 15.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 PFH33885.1 - 0.0007 19.8 2.9 0.013 15.7 0.6 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PFH33885.1 - 0.002 16.9 1.0 0.0093 14.7 0.9 1.9 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 PFH33885.1 - 0.0039 16.5 0.1 0.01 15.2 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 PFH33885.1 - 0.004 16.6 1.7 0.0072 15.7 1.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 PFH33885.1 - 0.0074 15.4 0.3 0.011 14.9 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 PFH33885.1 - 0.024 13.9 0.8 0.043 13.1 0.8 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 PFH33885.1 - 0.095 12.6 0.2 5.5 6.8 0.4 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 PFH33885.1 - 0.1 13.1 0.1 6.9 7.2 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain DAO PF01266.24 PFH33885.1 - 8.9 5.8 9.2 0.83 9.2 2.7 2.4 2 1 1 3 3 3 0 FAD dependent oxidoreductase PGA2 PF07543.12 PFH33886.1 - 2.5 8.1 4.8 15 5.5 4.8 2.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF872 PF05915.12 PFH33887.1 - 0.053 13.7 4.4 0.081 13.1 4.4 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) MFS_1 PF07690.16 PFH33889.1 - 3.7e-30 105.0 34.3 1.1e-21 77.1 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.29 PFH33890.1 - 9.2e-38 129.7 0.0 1.6e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH33890.1 - 6.3e-26 90.9 0.0 1.6e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.12 PFH33890.1 - 3.4e-10 40.1 0.0 8.8e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 PFH33890.1 - 5.6e-05 23.2 0.0 0.00015 21.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PFH33890.1 - 0.0077 16.5 0.2 0.06 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ERCC3_RAD25_C PF16203.5 PFH33890.1 - 0.076 12.2 0.0 0.18 10.9 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Bax1-I PF01027.20 PFH33891.1 - 5.2e-41 140.8 26.8 6e-41 140.5 26.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 PFH33891.1 - 0.00054 19.6 19.9 0.00073 19.2 19.9 1.2 1 0 0 1 1 1 1 Bax inhibitor 1 like DUF5383 PF17355.2 PFH33891.1 - 0.028 14.8 1.1 0.096 13.1 1.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5383) C2 PF00168.30 PFH33895.1 - 4.5e-37 126.5 0.2 3.7e-08 33.6 0.0 6.5 6 0 0 6 6 6 6 C2 domain Ferlin_C PF16165.5 PFH33895.1 - 0.0022 18.0 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 Ferlin C-terminus AP2 PF00847.20 PFH33896.1 - 2.4e-06 27.7 0.6 6.1e-06 26.4 0.1 1.9 2 0 0 2 2 2 1 AP2 domain SMC_N PF02463.19 PFH33897.1 - 8.9e-17 61.3 11.9 1.5e-07 31.1 12.5 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PFH33897.1 - 0.00011 22.2 0.8 0.019 14.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 PFH33897.1 - 0.0029 17.8 0.0 0.015 15.5 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 PFH33897.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Apt1 PF10351.9 PFH33898.1 - 0.22 10.4 0.9 0.27 10.1 0.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM199X PF15814.5 PFH33898.1 - 0.66 9.0 15.7 1.1 8.2 15.7 1.3 1 0 0 1 1 1 0 Protein family FAM199X SPX PF03105.19 PFH33898.1 - 1.5 8.6 6.5 3 7.6 6.5 1.5 1 0 0 1 1 1 0 SPX domain CCDC24 PF15669.5 PFH33898.1 - 2.5 7.9 8.9 21 4.9 0.0 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Macoilin PF09726.9 PFH33898.1 - 9.9 4.6 6.8 15 3.9 6.8 1.2 1 0 0 1 1 1 0 Macoilin family Nuf2 PF03800.14 PFH33899.1 - 5.7e-15 55.7 0.0 1.7e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 Nuf2 family Spc7 PF08317.11 PFH33899.1 - 0.0032 16.4 18.7 0.0032 16.4 18.7 2.5 2 1 0 2 2 2 1 Spc7 kinetochore protein Adaptin_N PF01602.20 PFH33900.1 - 2.4e-49 168.3 0.0 1.2e-46 159.4 0.0 3.5 2 1 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 PFH33900.1 - 5.5e-07 29.8 0.3 1.6e-06 28.3 0.1 1.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HD_3 PF13023.6 PFH33901.1 - 8.7e-41 139.6 0.1 5.2e-40 137.1 0.1 2.0 1 1 0 1 1 1 1 HD domain HD_2 PF12917.7 PFH33901.1 - 2.5e-11 43.7 0.0 8.7e-11 41.9 0.0 1.8 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 PFH33901.1 - 0.0022 18.2 0.1 0.0069 16.6 0.1 1.9 1 1 0 1 1 1 1 HD domain zf-RING_UBOX PF13445.6 PFH33902.1 - 4.6e-06 26.6 5.4 4.6e-06 26.6 5.4 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-B_box PF00643.24 PFH33902.1 - 3.8e-05 23.8 1.3 3.8e-05 23.8 1.3 2.3 2 1 0 2 2 2 1 B-box zinc finger zf-C3HC4 PF00097.25 PFH33902.1 - 8.6e-05 22.3 4.6 8.6e-05 22.3 4.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PFH33902.1 - 0.00014 22.2 6.9 0.00014 22.2 6.9 2.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 PFH33902.1 - 0.00037 20.6 4.7 0.00037 20.6 4.7 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PFH33902.1 - 0.0063 16.5 5.1 0.0063 16.5 5.1 2.7 3 0 0 3 3 3 1 zinc-RING finger domain FYVE PF01363.21 PFH33902.1 - 0.06 13.5 6.4 0.53 10.5 1.2 2.5 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_11 PF17123.5 PFH33902.1 - 2.4 8.0 9.0 5.2 6.9 9.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 PFH33902.1 - 5.7 6.9 16.8 0.045 13.6 7.7 2.3 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.25 PFH33903.1 - 6.9e-21 74.6 0.1 6.5e-17 61.6 0.0 4.3 4 1 0 4 4 4 1 short chain dehydrogenase adh_short_C2 PF13561.6 PFH33903.1 - 4.1e-08 33.1 1.0 2.4e-05 24.0 0.0 3.1 3 1 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PFH33903.1 - 0.00034 20.6 0.3 0.00089 19.2 0.1 1.8 2 0 0 2 2 2 1 KR domain ThiF PF00899.21 PFH33903.1 - 0.041 13.2 0.2 0.072 12.4 0.2 1.3 1 0 0 1 1 1 0 ThiF family CorA PF01544.18 PFH33905.1 - 0.00014 21.3 0.2 0.00042 19.7 0.2 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF998 PF06197.13 PFH33905.1 - 0.17 11.4 3.3 0.45 10.1 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF998) ArfGap PF01412.18 PFH33906.1 - 1.8e-40 137.7 0.1 1.8e-40 137.7 0.1 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Plasmodium_Vir PF05795.11 PFH33906.1 - 0.11 11.9 2.0 0.17 11.3 2.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Apt1 PF10351.9 PFH33906.1 - 0.89 8.3 5.1 1.1 8.1 5.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RNA_pol_Rpc4 PF05132.14 PFH33906.1 - 1.7 9.1 6.4 5.1 7.5 6.4 1.8 1 0 0 1 1 1 0 RNA polymerase III RPC4 Rtf2 PF04641.12 PFH33906.1 - 4.1 6.7 8.7 7.8 5.8 8.7 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger RR_TM4-6 PF06459.12 PFH33906.1 - 5.3 6.8 6.6 8.3 6.1 6.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TraV PF09676.10 PFH33906.1 - 8.2 7.4 17.5 0.43 11.6 10.9 2.3 2 1 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) AhpC-TSA PF00578.21 PFH33907.1 - 2.6e-26 92.0 0.0 4.2e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 PFH33907.1 - 1.1e-13 50.7 0.2 1.8e-13 50.1 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 PFH33907.1 - 1.4e-11 44.3 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 PFH33907.1 - 0.053 13.6 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme zf-CCCH PF00642.24 PFH33908.1 - 6.7e-08 32.3 9.3 0.00063 19.6 2.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PFH33908.1 - 0.002 17.9 9.7 0.14 12.0 0.7 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 PFH33908.1 - 0.0038 17.9 5.0 0.099 13.3 0.5 2.2 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 PFH33908.1 - 0.0079 16.2 11.4 0.041 14.0 1.9 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 PFH33908.1 - 1.3 9.3 2.6 7.2 6.9 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 PFH33908.1 - 2.5 8.7 7.5 4.9 7.8 1.0 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF2625 PF10946.8 PFH33909.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2625 Herpes_LMP1 PF05297.11 PFH33909.1 - 2.1 7.5 8.3 3.5 6.7 8.3 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) TAFII55_N PF04658.13 PFH33910.1 - 4.5e-18 65.5 0.0 4.5e-18 65.5 0.0 2.5 3 0 0 3 3 3 1 TAFII55 protein conserved region T3SS_needle_E PF08988.10 PFH33910.1 - 0.56 10.4 7.9 10 6.3 0.0 2.9 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle TFIIA PF03153.13 PFH33910.1 - 9 6.2 10.6 1.4 8.8 1.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ANAPC4_WD40 PF12894.7 PFH33912.1 - 3.5e-12 46.4 0.1 0.077 13.3 0.0 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PFH33912.1 - 7.5e-11 42.4 1.5 0.0013 19.5 0.1 5.5 5 0 0 5 5 5 1 WD domain, G-beta repeat LisH PF08513.11 PFH33912.1 - 7.7e-07 28.9 0.3 1.7e-06 27.8 0.3 1.6 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 PFH33912.1 - 0.00011 21.3 0.0 0.00098 18.2 0.0 2.3 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 PFH33912.1 - 0.28 9.1 0.1 0.99 7.3 0.3 1.6 2 0 0 2 2 2 0 IKI3 family Ribosomal_L4 PF00573.22 PFH33913.1 - 1.5e-39 135.7 0.6 3.3e-39 134.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 PFH33913.1 - 1e-24 86.4 2.2 1e-24 86.4 2.2 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain tRNA_Me_trans PF03054.16 PFH33914.1 - 4.3e-70 236.3 0.0 3.1e-34 118.3 0.0 4.5 5 0 0 5 5 5 4 tRNA methyl transferase SufE PF02657.15 PFH33914.1 - 3.6e-07 30.1 0.0 1.8e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Fe-S metabolism associated domain Asn_synthase PF00733.21 PFH33914.1 - 0.0037 17.0 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 PFH33914.1 - 0.099 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Peroxin-3 PF04882.12 PFH33916.1 - 0.83 8.6 5.7 0.9 8.5 0.0 3.3 4 0 0 4 4 4 0 Peroxin-3 PhaP_Bmeg PF09602.10 PFH33917.1 - 0.029 14.3 9.4 0.057 13.3 9.4 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Acetyltransf_11 PF13720.6 PFH33917.1 - 0.24 11.9 0.9 0.8 10.2 0.9 1.8 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 BAR_3 PF16746.5 PFH33917.1 - 0.34 10.6 11.0 0.15 11.7 0.2 2.8 3 0 0 3 3 3 0 BAR domain of APPL family DUF4612 PF15389.6 PFH33917.1 - 3.6 8.7 7.7 1.9 9.5 4.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4612) GAS PF13851.6 PFH33917.1 - 5.3 6.3 28.5 0.011 15.1 11.9 2.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding HU-CCDC81_bac_1 PF18174.1 PFH33920.1 - 0.0078 16.1 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 1 UCH PF00443.29 PFH33921.1 - 5.2e-32 111.3 0.0 4.4e-31 108.3 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PFH33921.1 - 2.2e-11 43.9 0.0 1.4e-09 38.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Adaptin_binding PF10199.9 PFH33922.1 - 1.4e-10 41.8 1.5 1.4e-10 41.8 1.5 2.3 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Peptidase_S15 PF02129.18 PFH33922.1 - 0.054 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SLBP_RNA_bind PF15247.6 PFH33923.1 - 2.3e-23 82.1 2.4 2.3e-23 82.1 2.4 2.2 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain ATP_bind_3 PF01171.20 PFH33927.1 - 1.1e-17 64.4 0.0 3.9e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 PP-loop family zn-ribbon_14 PF16503.5 PFH33927.1 - 3.9e-07 29.5 0.9 3.9e-07 29.5 0.9 2.8 3 0 0 3 3 3 1 Zinc-ribbon PAPS_reduct PF01507.19 PFH33927.1 - 0.0098 15.9 0.0 0.82 9.7 0.0 2.3 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family tRNA_Me_trans PF03054.16 PFH33927.1 - 0.032 13.0 0.0 0.11 11.2 0.0 1.8 2 0 0 2 2 2 0 tRNA methyl transferase RecR PF02132.15 PFH33927.1 - 0.048 13.2 0.3 0.048 13.2 0.3 3.4 4 0 0 4 4 4 0 RecR protein EFP PF01132.20 PFH33928.1 - 1.5e-06 28.1 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain EFP_N PF08207.12 PFH33928.1 - 7.4e-05 22.7 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain DUF4575 PF15143.6 PFH33928.1 - 0.066 13.4 4.8 0.1 12.8 4.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4575) Integrase_DNA PF02920.15 PFH33929.1 - 0.032 13.9 0.1 0.053 13.2 0.1 1.3 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase PEX-1N PF09262.11 PFH33936.1 - 5.4e-10 39.5 0.0 9.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA PF00004.29 PFH33937.1 - 3.2e-40 137.6 0.0 8e-40 136.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PFH33937.1 - 0.00094 19.5 0.0 0.62 10.3 0.1 3.4 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 PFH33937.1 - 0.0014 18.8 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 PFH33937.1 - 0.0021 18.5 0.9 0.072 13.5 0.2 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 PFH33937.1 - 0.0026 17.8 0.0 0.012 15.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 PFH33937.1 - 0.0058 16.4 1.4 3.5 7.5 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain Mg_chelatase PF01078.21 PFH33937.1 - 0.021 14.2 0.1 0.052 12.9 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 PFH33937.1 - 0.029 14.5 0.0 0.23 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 PFH33937.1 - 0.065 13.0 0.0 0.23 11.2 0.0 1.9 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 PFH33937.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PFH33937.1 - 0.075 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.15 PFH33937.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 PFH33937.1 - 0.2 11.2 0.0 0.67 9.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region His_Phos_2 PF00328.22 PFH33939.1 - 0.02 14.3 0.1 0.31 10.3 0.0 2.4 3 0 0 3 3 3 0 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 PFH33940.1 - 0.045 13.1 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Ribosomal_L33 PF00471.20 PFH33941.1 - 1.1e-07 32.1 0.4 1.1e-07 32.1 0.4 2.2 3 0 0 3 3 3 1 Ribosomal protein L33 RRM_1 PF00076.22 PFH33942.1 - 2.9e-18 65.4 0.2 3.8e-06 26.6 0.0 4.5 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PFH33942.1 - 3.8e-05 23.5 0.0 1.9 8.4 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif RL PF17797.1 PFH33942.1 - 0.0053 16.7 0.0 0.21 11.6 0.0 2.5 2 0 0 2 2 2 1 RL domain SH2_2 PF14633.6 PFH33943.1 - 9.1e-14 51.4 2.4 7.4e-12 45.1 0.0 3.9 3 1 0 3 3 3 1 SH2 domain HHH_7 PF14635.6 PFH33943.1 - 7.8e-13 48.7 0.0 3.4e-11 43.4 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HTH_44 PF14641.6 PFH33943.1 - 2.5e-06 27.9 1.6 2.5e-06 27.9 1.6 2.3 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 PFH33943.1 - 7.3e-06 26.5 24.2 7.3e-06 26.5 24.2 14.2 13 2 2 16 16 16 1 Acidic N-terminal SPT6 SR-25 PF10500.9 PFH33943.1 - 0.0025 17.5 17.1 0.0025 17.5 17.1 5.3 5 1 1 6 6 6 1 Nuclear RNA-splicing-associated protein HHH_9 PF17674.1 PFH33943.1 - 0.26 12.2 1.4 16 6.4 0.0 3.7 3 0 0 3 3 3 0 HHH domain IMS PF00817.20 PFH33944.1 - 4.6e-24 85.1 0.0 1.9e-13 50.7 0.0 3.1 2 1 0 2 2 2 2 impB/mucB/samB family IMS_C PF11799.8 PFH33944.1 - 0.00095 19.9 0.1 0.011 16.4 0.1 2.6 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 PFH33944.1 - 0.014 15.6 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif zf-CCCH_2 PF14608.6 PFH33945.1 - 3.8e-07 30.3 31.2 0.00085 19.7 4.4 3.4 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 PFH33945.1 - 0.00023 20.9 15.1 0.1 12.4 0.5 3.6 3 0 0 3 3 3 3 CCCH-type zinc finger PWI PF01480.17 PFH33945.1 - 0.0067 16.7 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 PWI domain zf_CCCH_4 PF18345.1 PFH33945.1 - 0.018 15.1 14.9 0.15 12.1 0.5 3.7 3 0 0 3 3 3 0 Zinc finger domain Nab2p_Zf1 PF18260.1 PFH33945.1 - 0.072 13.0 6.3 0.28 11.1 1.6 2.5 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 zf-CCHH PF10283.9 PFH33945.1 - 1.9 8.5 11.5 9.4 6.3 0.9 3.5 3 0 0 3 3 3 0 PBZ domain zf-CCCH PF00642.24 PFH33945.1 - 6.8 6.7 17.5 0.24 11.3 0.7 3.7 2 1 1 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Prominin PF05478.11 PFH33946.1 - 0.37 8.7 5.6 0.56 8.1 5.6 1.1 1 0 0 1 1 1 0 Prominin AAA_25 PF13481.6 PFH33947.1 - 0.0054 16.3 0.4 0.022 14.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PFH33947.1 - 0.09 13.2 1.9 0.17 12.2 0.2 2.3 2 0 0 2 2 2 0 AAA ATPase domain DSPc PF00782.20 PFH33948.1 - 2.2e-31 108.4 0.0 2.6e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 PFH33948.1 - 0.00042 20.5 0.0 0.00056 20.1 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 PFH33948.1 - 0.0042 17.4 0.1 0.007 16.7 0.0 1.4 1 1 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 PFH33948.1 - 0.0043 16.6 0.2 0.0072 15.9 0.2 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Ank_2 PF12796.7 PFH33949.1 - 2.8e-28 98.3 1.6 1.1e-10 42.0 2.5 4.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PFH33949.1 - 5.2e-27 93.6 9.0 4.7e-10 39.5 0.1 5.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 PFH33949.1 - 1.4e-25 89.3 3.9 2.9e-07 30.9 0.1 5.8 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 PFH33949.1 - 2.2e-23 81.6 9.7 0.00022 21.5 0.2 8.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 PFH33949.1 - 6e-22 75.4 5.7 0.00029 21.0 0.0 7.4 7 1 0 7 7 7 5 Ankyrin repeat Sushi PF00084.20 PFH33949.1 - 1.7e-06 28.5 0.2 3.6e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) JAB PF01398.21 PFH33950.1 - 1.6e-25 89.3 0.0 2.8e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 PFH33950.1 - 3.8e-06 26.7 0.0 1.1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain CSN5_C PF18323.1 PFH33950.1 - 1.2e-05 26.1 0.2 0.17 12.8 0.1 2.3 2 0 0 2 2 2 2 Cop9 signalosome subunit 5 C-terminal domain Lon_C PF05362.13 PFH33951.1 - 7.8e-67 224.8 0.6 2.1e-56 190.7 0.1 3.5 3 0 0 3 3 3 2 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 PFH33951.1 - 6.5e-22 78.4 0.0 2.2e-21 76.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 PFH33951.1 - 6.5e-17 62.1 0.2 1.8e-15 57.4 0.0 2.6 2 1 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 PFH33951.1 - 9.2e-08 32.2 0.0 2.5e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 PFH33951.1 - 2.9e-07 30.4 0.0 5.9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 PFH33951.1 - 3.5e-06 27.3 0.0 1.3e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PFH33951.1 - 2e-05 24.9 1.5 7.8e-05 23.0 0.0 2.7 3 1 0 3 3 2 1 AAA domain AAA_PrkA PF08298.11 PFH33951.1 - 5.6e-05 22.2 0.0 9.5e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 PFH33951.1 - 8.2e-05 23.0 0.1 0.001 19.5 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 PFH33951.1 - 0.00098 19.7 0.4 0.0044 17.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 PFH33951.1 - 0.002 17.9 0.0 0.0093 15.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 PFH33951.1 - 0.003 17.3 0.0 0.0082 15.9 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_3 PF07726.11 PFH33951.1 - 0.024 14.5 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 PFH33951.1 - 0.038 13.2 1.0 0.06 12.5 0.1 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain RsgA_GTPase PF03193.16 PFH33951.1 - 0.04 13.8 0.3 0.099 12.5 0.0 1.8 2 0 0 2 2 1 0 RsgA GTPase RNA_helicase PF00910.22 PFH33951.1 - 0.073 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 PFH33951.1 - 0.081 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2178 PF09946.9 PFH33952.1 - 0.42 10.8 0.0 0.42 10.8 0.0 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2178) Methyltr_RsmB-F PF01189.17 PFH33953.1 - 8.4e-36 123.5 0.0 1.4e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PUA PF01472.20 PFH33953.1 - 5.6e-05 23.0 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 PUA domain FtsJ PF01728.19 PFH33953.1 - 0.0014 18.7 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 PFH33953.1 - 0.0015 18.3 0.0 0.11 12.3 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH33953.1 - 0.027 15.2 1.2 0.49 11.1 0.0 3.5 5 0 0 5 5 5 0 Methyltransferase domain PCMT PF01135.19 PFH33953.1 - 0.051 13.3 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fibrillarin PF01269.17 PFH33953.1 - 0.2 10.8 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Proteasom_PSMB PF10508.9 PFH33954.1 - 4e-19 68.5 0.0 2.8e-18 65.7 0.0 1.9 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.20 PFH33954.1 - 0.027 13.0 0.1 0.074 11.6 0.1 1.6 1 1 0 1 1 1 0 Adaptin N terminal region WRNPLPNID PF15017.6 PFH33955.1 - 0.56 11.1 4.7 0.77 10.7 0.5 3.1 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Proteasome PF00227.26 PFH33956.1 - 1e-47 162.1 0.5 1.3e-47 161.8 0.5 1.1 1 0 0 1 1 1 1 Proteasome subunit RAP PF08373.10 PFH33957.1 - 7.7e-16 57.9 0.0 1.2e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 PFH33957.1 - 0.063 13.5 0.0 3.1 8.0 0.0 2.4 1 1 0 1 1 1 0 REase_MTES_1575 YabA PF06156.13 PFH33958.1 - 0.75 10.5 17.2 0.25 12.0 1.7 3.4 2 1 1 3 3 3 0 Initiation control protein YabA GldM_N PF12081.8 PFH33958.1 - 1.1 9.3 8.3 3.3 7.7 0.7 3.0 3 0 0 3 3 3 0 GldM N-terminal domain DUF2508 PF10704.9 PFH33958.1 - 1.2 9.3 3.9 3.4 7.9 3.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) tRNA_synthFbeta PF17759.1 PFH33959.1 - 1.2e-33 116.4 0.0 1e-32 113.3 0.0 2.0 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 PFH33959.1 - 1e-29 102.6 0.0 2.6e-29 101.3 0.0 1.7 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 PFH33959.1 - 5.6e-22 78.2 0.0 1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 PFH33959.1 - 5.3e-14 52.3 0.0 4.4e-12 46.1 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain Thymidylate_kin PF02223.17 PFH33960.1 - 4.1e-33 114.6 0.0 2e-24 86.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase APS_kinase PF01583.20 PFH33960.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase JmjC PF02373.22 PFH33963.1 - 1.4e-35 122.2 0.4 2.5e-35 121.3 0.4 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 PFH33963.1 - 0.00017 21.5 0.0 0.00037 20.4 0.0 1.6 1 0 0 1 1 1 1 jmjN domain DUF4570 PF15134.6 PFH33963.1 - 0.00061 19.8 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) PNP_UDP_1 PF01048.20 PFH33965.1 - 5e-33 114.3 0.2 5.9e-33 114.1 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Rrp15p PF07890.12 PFH33966.1 - 4.2e-13 49.8 6.6 4.2e-13 49.8 6.6 1.7 2 0 0 2 2 2 1 Rrp15p DUF442 PF04273.13 PFH33967.1 - 0.064 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) PLN_propep PF16485.5 PFH33968.1 - 0.12 12.2 0.2 0.68 9.7 0.1 2.3 2 0 0 2 2 2 0 Protealysin propeptide RRM_1 PF00076.22 PFH33970.1 - 1e-20 73.3 0.0 3.4e-11 42.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PFH33970.1 - 2.6e-08 33.6 0.0 0.0035 17.1 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 PFH33970.1 - 0.00011 21.8 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 PFH33970.1 - 0.00067 19.5 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) Calcipressin PF04847.12 PFH33970.1 - 0.029 14.1 4.4 0.38 10.5 0.0 2.9 2 1 1 3 3 3 0 Calcipressin Nup35_RRM_2 PF14605.6 PFH33970.1 - 0.045 13.8 0.1 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF3947 PF13135.6 PFH33970.1 - 0.1 12.8 3.0 0.29 11.4 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) Picorna_P3A PF06363.11 PFH33970.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Picornaviridae P3A protein PHM7_cyt PF14703.6 PFH33970.1 - 0.48 10.7 1.6 33 4.6 0.0 2.7 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Ribosomal_60s PF00428.19 PFH33971.1 - 1.6e-22 79.9 12.1 1.9e-22 79.7 12.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 PFH33971.1 - 5.8 7.6 6.3 8.3 7.1 6.3 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Ribosomal_L5_C PF00673.21 PFH33972.1 - 5.5e-23 81.0 0.0 8.6e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 PFH33972.1 - 5.2e-21 74.7 0.0 8.5e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 PFH33972.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain PX PF00787.24 PFH33974.1 - 7.3e-21 74.3 0.1 4.8e-20 71.6 0.0 2.3 3 0 0 3 3 3 1 PX domain Syntaxin-6_N PF09177.11 PFH33974.1 - 0.18 12.3 2.7 33 5.1 0.0 3.5 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Hydrolase_4 PF12146.8 PFH33977.1 - 0.00023 20.5 0.2 0.39 9.9 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PFH33977.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Aa_trans PF01490.18 PFH33978.1 - 1.5e-05 23.9 0.2 1.5e-05 23.9 0.2 3.9 5 0 0 5 5 5 3 Transmembrane amino acid transporter protein Apolipoprotein PF01442.18 PFH33979.1 - 0.0019 18.1 0.8 0.0036 17.2 0.8 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Melibiase_2 PF16499.5 PFH33980.1 - 4.8e-82 275.3 0.2 7.3e-82 274.7 0.2 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 PFH33980.1 - 4.4e-08 33.1 0.0 3.8e-06 26.9 0.0 3.4 2 1 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 PFH33980.1 - 0.00035 19.6 0.0 0.00056 19.0 0.0 1.2 1 0 0 1 1 1 1 Melibiase Melibiase_2_C PF17450.2 PFH33980.1 - 0.0015 18.7 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain PLDc_2 PF13091.6 PFH33981.1 - 3.5e-23 82.0 0.0 7e-08 32.4 0.0 4.3 4 0 0 4 4 4 4 PLD-like domain PLDc PF00614.22 PFH33981.1 - 7e-11 41.8 0.5 0.00022 21.3 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 PFH33981.1 - 0.13 11.4 0.0 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB NLE PF08154.12 PFH33984.1 - 1.4e-18 67.2 0.1 2.3e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 PFH33984.1 - 2.1e-08 34.7 5.9 0.082 13.8 0.3 6.4 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH33984.1 - 1.2e-05 25.5 0.0 0.46 10.8 0.0 4.3 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_6 PF12774.7 PFH33986.1 - 1.6e-141 471.1 0.0 6.5e-141 469.0 0.0 2.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 PFH33986.1 - 4.8e-139 464.6 6.1 4.8e-139 464.6 6.1 2.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 PFH33986.1 - 7.4e-117 390.8 4.6 7.4e-117 390.8 4.6 4.8 8 0 0 8 8 8 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PFH33986.1 - 9.5e-86 287.3 0.0 4e-85 285.3 0.0 2.0 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PFH33986.1 - 1e-78 264.7 0.7 1.1e-77 261.3 0.0 3.3 5 0 0 5 5 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PFH33986.1 - 7.4e-77 257.4 0.0 3.4e-76 255.2 0.0 2.3 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 PFH33986.1 - 6.8e-68 227.7 0.3 1.2e-60 204.1 0.0 4.2 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PFH33986.1 - 9.4e-54 181.6 0.0 2.3e-53 180.4 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 PFH33986.1 - 1.8e-44 152.2 9.6 3.1e-44 151.4 9.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PFH33986.1 - 5.1e-39 133.0 0.0 2.4e-38 130.9 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PFH33986.1 - 1.2e-26 93.3 0.0 1.2e-25 90.0 0.0 3.0 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PFH33986.1 - 5.1e-25 88.1 0.8 1.2e-06 28.6 0.0 5.6 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PFH33986.1 - 5.8e-17 61.7 0.0 2.6e-16 59.6 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 PFH33986.1 - 5.3e-10 39.9 15.8 0.00042 20.7 0.0 8.5 8 0 0 8 8 7 2 AAA ATPase domain AAA_22 PF13401.6 PFH33986.1 - 2.2e-08 34.5 1.0 0.12 12.6 0.0 6.2 6 0 0 6 6 5 2 AAA domain AAA PF00004.29 PFH33986.1 - 2.7e-05 24.6 0.4 0.39 11.1 0.0 3.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 PFH33986.1 - 3.9e-05 23.5 2.0 1.2 8.8 0.0 4.9 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 PFH33986.1 - 0.00035 21.1 0.0 1.2 9.7 0.0 4.2 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 PFH33986.1 - 0.011 15.4 0.1 4 7.1 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 PFH33986.1 - 0.019 14.4 0.1 8 5.7 0.0 3.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_29 PF13555.6 PFH33986.1 - 0.02 14.7 0.4 5.2 6.9 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain T2SSE PF00437.20 PFH33986.1 - 0.022 13.8 0.0 0.64 9.0 0.0 2.8 2 0 0 2 2 2 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 PFH33986.1 - 0.025 14.5 0.1 0.2 11.6 0.0 2.6 3 0 0 3 3 1 0 RsgA GTPase Stork_head PF10264.9 PFH33986.1 - 0.042 14.0 0.0 2.3 8.5 0.0 3.7 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain RNA_helicase PF00910.22 PFH33986.1 - 0.046 14.1 0.0 24 5.4 0.0 3.1 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 PFH33986.1 - 0.051 13.0 0.1 0.8 9.1 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 PFH33986.1 - 0.052 13.8 1.6 16 5.7 0.0 4.3 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 PFH33986.1 - 0.053 13.9 0.8 70 3.7 0.0 4.0 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 PFH33986.1 - 0.24 11.9 1.7 1.9 9.0 0.0 3.5 4 0 0 4 4 1 0 ABC transporter COG2 PF06148.11 PFH33986.1 - 1.6 8.8 8.6 31 4.7 0.0 4.7 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF16 PF01519.16 PFH33986.1 - 4.9 7.7 9.3 31 5.1 1.8 4.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 SOAR PF16533.5 PFH33986.1 - 6.1 6.9 13.2 0.51 10.3 1.1 4.2 3 0 0 3 3 2 0 STIM1 Orai1-activating region Adaptin_binding PF10199.9 PFH33986.1 - 7.6 7.2 9.3 0.44 11.2 0.1 3.5 3 1 0 3 3 2 0 Alpha and gamma adaptin binding protein p34 SAG PF04092.13 PFH33989.1 - 8.1e-15 55.8 9.2 1.1e-07 32.7 0.6 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH33990.1 - 2.3e-18 67.2 18.4 1.5e-05 25.8 0.6 3.8 3 1 0 3 3 3 3 SRS domain SAG PF04092.13 PFH33991.1 - 4.4e-07 30.7 0.0 5.4e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH33992.1 - 3.3e-16 60.3 4.8 2.4e-08 34.8 0.9 2.2 2 0 0 2 2 2 2 SRS domain Cytochrom_B_C PF00032.17 PFH33993.1 - 1.1e-12 48.1 0.1 1.8e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Corona_3 PF04694.12 PFH33993.1 - 0.00069 19.9 0.1 0.0023 18.2 0.0 1.8 2 0 0 2 2 2 1 Coronavirus ORF3 protein Lung_7-TM_R PF06814.13 PFH33994.1 - 4.1e-50 170.7 20.0 6.1e-50 170.1 20.0 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 PFH33994.1 - 4.1e-07 29.7 23.4 5.6e-07 29.2 21.7 1.9 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain TFIIE-A_C PF11521.8 PFH33994.1 - 0.19 12.1 2.8 1.4 9.3 0.0 2.7 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha DUF3681 PF12442.8 PFH33994.1 - 0.36 11.3 6.7 0.58 10.7 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) Sushi PF00084.20 PFH33995.1 - 9.4e-14 51.8 0.2 1.9e-13 50.7 0.2 1.5 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Lin-8 PF03353.15 PFH33995.1 - 0.0017 18.0 2.6 0.0017 18.0 2.6 3.3 2 1 1 3 3 3 1 Ras-mediated vulval-induction antagonist Tagatose_6_P_K PF08013.11 PFH33996.1 - 0.079 11.6 0.3 0.13 10.9 0.3 1.2 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase bZIP_Maf PF03131.17 PFH33998.1 - 0.77 10.3 4.3 0.76 10.3 0.8 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor CAML PF14963.6 PFH33999.1 - 7.6 6.6 5.7 4.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand CAP_C PF08603.11 PFH34001.1 - 1.8e-53 180.4 3.2 2.2e-53 180.1 3.2 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 PFH34001.1 - 7.9e-07 28.8 2.6 1.1e-06 28.4 2.6 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF5497 PF17601.2 PFH34001.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5497) Coat_X PF07552.11 PFH34001.1 - 0.15 11.9 8.7 5.9 6.8 0.2 3.4 2 1 1 3 3 3 0 Spore Coat Protein X and V domain UQ_con PF00179.26 PFH34002.1 - 1.5e-14 53.9 0.0 1.9e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RRM_1 PF00076.22 PFH34003.1 - 2.2e-21 75.4 0.2 3e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH34003.1 - 0.0075 16.4 0.0 0.042 14.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif RNase_T PF00929.24 PFH34005.1 - 4.7e-30 105.3 0.0 5.6e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Methyltransf_31 PF13847.6 PFH34006.1 - 6.1e-14 52.1 0.0 7.7e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH34006.1 - 4.9e-13 49.6 0.1 9.7e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PFH34006.1 - 8.7e-13 48.7 0.1 1.4e-12 48.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH34006.1 - 2.7e-07 31.3 0.0 4.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PFH34006.1 - 8.5e-07 28.9 0.0 1.5e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PFH34006.1 - 2.2e-05 23.9 0.0 3.1e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 PFH34006.1 - 0.00033 20.1 0.0 0.0005 19.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB TPMT PF05724.11 PFH34006.1 - 0.0026 17.4 0.0 0.0042 16.8 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PcrB PF01884.17 PFH34006.1 - 0.04 13.4 0.0 0.077 12.4 0.0 1.4 1 1 0 1 1 1 0 PcrB family CMAS PF02353.20 PFH34006.1 - 0.054 12.8 0.0 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 PFH34006.1 - 0.14 12.0 0.2 1.1 9.1 0.1 2.0 1 1 1 2 2 2 0 Hypothetical methyltransferase AMP-binding PF00501.28 PFH34007.1 - 2.5e-70 237.2 0.0 6e-70 236.0 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PFH34007.1 - 0.00045 21.1 0.0 0.0012 19.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HLH PF00010.26 PFH34007.1 - 0.24 11.4 0.8 0.46 10.5 0.8 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Mannosyl_trans PF05007.13 PFH34008.1 - 1.4e-59 202.1 15.4 1.1e-42 146.7 12.8 2.3 1 1 0 2 2 2 2 Mannosyltransferase (PIG-M) DAP3 PF10236.9 PFH34009.1 - 4.4e-20 72.1 0.0 9.4e-09 34.9 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 PFH34009.1 - 0.093 13.1 4.4 0.12 12.8 0.0 2.9 1 1 1 2 2 2 0 AAA ATPase domain GCP_N_terminal PF17681.1 PFH34010.1 - 3.6e-61 207.5 0.0 7.6e-61 206.4 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 PFH34010.1 - 8.2e-26 91.2 2.4 7.2e-13 48.7 0.1 3.0 3 0 0 3 3 3 2 Gamma tubulin complex component C-terminal DUF664 PF04978.12 PFH34010.1 - 0.035 14.5 0.4 0.035 14.5 0.4 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF664) PIEZO PF15917.5 PFH34010.1 - 1.2 8.6 3.6 2.7 7.4 3.6 1.6 1 0 0 1 1 1 0 Piezo LMBR1 PF04791.16 PFH34011.1 - 2.4e-21 76.3 0.0 2.1e-15 56.7 0.0 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF2852 PF11014.8 PFH34011.1 - 0.065 13.4 0.5 0.14 12.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) AMP-binding PF00501.28 PFH34012.1 - 2e-72 244.1 0.0 6.6e-72 242.4 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme 3HCDH_N PF02737.18 PFH34012.1 - 0.2 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HEAT PF02985.22 PFH34015.1 - 0.00018 21.5 14.5 0.03 14.6 0.6 5.9 5 0 0 5 5 5 3 HEAT repeat WD40 PF00400.32 PFH34015.1 - 0.0072 17.1 0.1 5.1 8.1 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat Kinase-like PF14531.6 PFH34017.1 - 3.3e-49 167.8 0.0 4.5e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH34017.1 - 6.5e-22 78.1 0.0 8.1e-15 54.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34017.1 - 4.4e-06 26.2 0.0 3.9e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH34017.1 - 0.011 15.7 0.1 0.042 13.8 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 PFH34017.1 - 0.094 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 PFH34017.1 - 0.22 11.1 0.0 0.95 9.0 0.0 1.9 2 0 0 2 2 2 0 RIO1 family LacY_symp PF01306.19 PFH34018.1 - 0.0075 15.1 1.0 0.0075 15.1 1.0 2.2 2 0 0 2 2 2 1 LacY proton/sugar symporter GBP PF02263.19 PFH34019.1 - 1e-19 70.8 0.0 1.7e-15 57.0 0.0 3.3 3 0 0 3 3 3 3 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 PFH34019.1 - 1.5e-08 34.4 6.5 2.5e-08 33.7 6.5 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain DUF2859 PF11072.8 PFH34019.1 - 0.035 13.8 0.5 0.48 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) Fez1 PF06818.15 PFH34019.1 - 0.14 12.6 16.2 0.28 11.6 16.2 1.4 1 0 0 1 1 1 0 Fez1 PKcGMP_CC PF16808.5 PFH34019.1 - 0.4 10.6 3.0 1 9.3 3.0 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Dynamin_N PF00350.23 PFH34019.1 - 0.52 10.4 1.2 7.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Bestrophin PF01062.21 PFH34022.1 - 2.9e-13 49.9 4.3 1.2e-06 28.1 1.7 3.0 2 1 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF2628 PF10947.8 PFH34022.1 - 0.0023 18.3 0.4 0.0023 18.3 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2628) DUF2177 PF09945.9 PFH34022.1 - 0.21 11.7 4.1 0.61 10.2 4.1 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) Mic1 PF07035.12 PFH34023.1 - 5.3e-07 29.5 0.9 3.8e-06 26.7 0.9 2.1 1 1 0 1 1 1 1 Colon cancer-associated protein Mic1-like CTP_transf_like PF01467.26 PFH34025.1 - 1.3e-40 138.9 0.0 2e-21 76.7 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 PFH34025.1 - 0.0059 16.5 0.7 1.5 8.7 0.1 2.7 2 1 0 2 2 2 2 FAD synthetase Pantoate_ligase PF02569.15 PFH34025.1 - 0.15 11.3 0.0 18 4.4 0.0 2.2 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase RCC1_2 PF13540.6 PFH34026.1 - 9.6e-27 92.2 13.7 2.4e-07 30.4 1.0 6.0 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 PFH34026.1 - 1.3e-18 67.4 20.1 4.4e-06 27.2 0.1 7.5 6 3 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.32 PFH34028.1 - 1.1e-12 48.2 0.2 0.035 15.0 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH34028.1 - 1.4e-09 38.1 0.0 0.14 12.4 0.0 4.8 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PFH34028.1 - 0.0016 17.5 0.6 0.11 11.4 0.1 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 PFH34028.1 - 0.13 11.5 0.0 7.8 5.6 0.0 2.7 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Frtz PF11768.8 PFH34028.1 - 0.35 9.1 0.0 0.63 8.3 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz IQCJ-SCHIP1 PF15157.6 PFH34028.1 - 2.2 8.1 4.2 32 4.3 1.8 2.8 2 1 1 3 3 3 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Calreticulin PF00262.18 PFH34029.1 - 3.7e-52 177.4 0.0 1.3e-43 149.3 0.0 2.1 2 0 0 2 2 2 2 Calreticulin family FTZ PF03867.14 PFH34030.1 - 0.93 9.0 4.4 2.4 7.6 4.4 1.6 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region CENP-B_dimeris PF09026.10 PFH34030.1 - 2.6 8.5 14.6 9.5 6.7 0.2 3.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MAR_sialic_bdg PF10564.9 PFH34031.1 - 1.7e-35 120.9 15.8 7.2e-28 96.5 3.4 3.0 2 1 1 3 3 3 2 Sialic-acid binding micronemal adhesive repeat PGAP1 PF07819.13 PFH34032.1 - 0.00037 20.3 0.0 0.00068 19.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 PFH34032.1 - 0.0044 16.3 0.0 0.01 15.1 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 PFH34032.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Cucumo_2B PF03263.13 PFH34034.1 - 2.3 8.7 6.7 2.1 8.8 3.8 2.6 2 0 0 2 2 2 0 Cucumovirus protein 2B Brix PF04427.18 PFH34036.1 - 2.3e-23 83.3 0.3 2.4e-18 67.0 0.0 2.2 1 1 1 2 2 2 2 Brix domain DUF2567 PF10821.8 PFH34037.1 - 0.15 12.1 2.9 0.11 12.6 1.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2567) Glyco_transf_8 PF01501.20 PFH34038.1 - 8.8e-11 41.8 0.2 3.9e-08 33.2 0.2 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 PFH34038.1 - 0.23 10.8 0.2 14 5.0 0.2 2.1 2 0 0 2 2 2 0 Mannosyltransferase putative WD40 PF00400.32 PFH34039.1 - 1.7e-12 47.6 26.5 0.064 14.1 0.2 9.5 10 2 0 10 10 10 5 WD domain, G-beta repeat HSP90 PF00183.18 PFH34041.1 - 2.1e-138 462.4 0.0 3.1e-88 297.0 0.0 2.1 2 0 0 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 PFH34041.1 - 3.5e-11 43.1 0.0 7.4e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PFH34041.1 - 9.2e-10 39.0 0.0 2.7e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SH3_14 PF18343.1 PFH34041.1 - 0.053 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Dda helicase SH3 domain MORN PF02493.20 PFH34042.1 - 8.1e-96 308.5 98.6 1.6e-09 37.1 1.4 14.8 15 0 0 15 15 15 14 MORN repeat DUF3048_C PF17479.2 PFH34042.1 - 0.0013 19.0 30.1 0.08 13.3 1.4 7.0 1 1 6 7 7 7 5 Protein of unknown function (DUF3048) C-terminal domain DUF2158 PF09926.9 PFH34042.1 - 0.056 13.2 9.1 3.6 7.4 0.3 6.0 3 3 3 6 6 6 0 Uncharacterized small protein (DUF2158) SH3_9 PF14604.6 PFH34042.1 - 4.8 7.1 14.4 22 5.0 0.1 5.6 4 1 1 5 5 5 0 Variant SH3 domain Spc7 PF08317.11 PFH34043.1 - 0.0011 18.0 22.1 0.0011 18.0 22.1 9.1 2 2 8 10 10 10 6 Spc7 kinetochore protein GAS PF13851.6 PFH34043.1 - 0.002 17.5 21.7 0.002 17.5 21.7 9.6 3 2 5 8 8 8 4 Growth-arrest specific micro-tubule binding LPP PF04728.13 PFH34043.1 - 0.0025 18.2 3.6 0.0025 18.2 3.6 11.0 9 3 1 10 10 10 1 Lipoprotein leucine-zipper DUF4201 PF13870.6 PFH34043.1 - 0.0034 17.1 12.7 0.0034 17.1 12.7 9.9 2 2 5 7 7 7 1 Domain of unknown function (DUF4201) HMMR_N PF15905.5 PFH34043.1 - 0.0049 16.4 19.8 0.0049 16.4 19.8 7.8 2 2 5 8 8 8 2 Hyaluronan mediated motility receptor N-terminal Sigma54_activ_2 PF14532.6 PFH34043.1 - 0.18 11.9 6.3 0.037 14.2 1.2 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain PCP PF02429.15 PFH34043.1 - 0.2 12.0 4.1 0.47 10.8 3.6 1.9 1 1 0 1 1 1 0 Peridinin-chlorophyll A binding protein DUF3584 PF12128.8 PFH34043.1 - 0.46 7.9 147.8 0.045 11.3 18.8 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) HsbA PF12296.8 PFH34043.1 - 2.6 8.5 22.5 4 7.9 8.5 4.7 3 1 1 4 4 4 0 Hydrophobic surface binding protein A Ras PF00071.22 PFH34044.1 - 3.1e-58 195.9 0.2 4.1e-58 195.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH34044.1 - 3.6e-36 124.0 0.1 6.1e-36 123.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH34044.1 - 3.5e-15 55.9 0.1 4.3e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PFH34044.1 - 6.9e-05 22.5 0.0 0.00019 21.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PFH34044.1 - 0.00056 19.4 0.0 0.00096 18.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PFH34044.1 - 0.00056 19.9 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 PFH34044.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PFH34044.1 - 0.0021 18.1 0.0 0.0037 17.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 PFH34044.1 - 0.0056 16.2 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 PFH34044.1 - 0.12 11.8 0.1 0.7 9.3 0.0 2.1 2 1 0 2 2 2 0 Bacterial TniB protein COX2 PF00116.20 PFH34045.1 - 4.6e-43 145.9 0.0 6e-43 145.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain ParcG PF10274.9 PFH34046.1 - 5.7e-43 147.2 0.1 1.4e-42 145.9 0.1 1.6 1 1 0 1 1 1 1 Parkin co-regulated protein Phage_holin_Dp1 PF16938.5 PFH34046.1 - 0.059 13.6 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Putative phage holin Dp-1 DCB PF16213.5 PFH34046.1 - 0.08 12.6 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Ribosomal_L27A PF00828.19 PFH34047.1 - 1e-23 84.4 0.0 1.4e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DNA_ligase_A_N PF04675.14 PFH34050.1 - 0.075 13.4 0.2 0.094 13.0 0.2 1.2 1 0 0 1 1 1 0 DNA ligase N terminus NfeD PF01957.18 PFH34050.1 - 0.11 12.9 0.1 0.24 11.8 0.0 1.6 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding PDEase_I PF00233.19 PFH34051.1 - 9.8e-61 205.5 0.0 1.5e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SNF2_N PF00176.23 PFH34052.1 - 1.4e-36 125.9 0.0 4.1e-31 108.0 0.1 2.4 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 PFH34052.1 - 1.6e-07 31.6 0.0 2.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 PFH34052.1 - 0.00051 19.9 0.4 0.00051 19.9 0.4 2.3 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_3 PF13920.6 PFH34052.1 - 0.00076 19.3 9.1 0.0022 17.8 1.6 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PFH34052.1 - 0.0019 18.0 2.1 0.0073 16.1 2.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PFH34052.1 - 0.0043 17.4 1.7 0.0043 17.4 1.7 3.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 PFH34052.1 - 0.005 16.8 0.4 0.005 16.8 0.4 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PFH34052.1 - 0.084 12.7 5.4 0.032 14.1 1.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PFH34052.1 - 0.089 12.7 7.3 0.43 10.5 2.7 3.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PFH34052.1 - 1 9.2 8.2 1.3 8.9 0.5 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 PFH34052.1 - 4.1 7.2 4.6 18 5.2 4.6 2.2 1 0 0 1 1 1 0 RING-like zinc finger PKD_channel PF08016.12 PFH34053.1 - 4.7e-10 38.7 41.6 0.00021 20.1 14.5 4.1 4 0 0 4 4 4 3 Polycystin cation channel DUF1654 PF07867.11 PFH34053.1 - 0.0013 18.4 0.1 0.0039 16.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1654) PAN_4 PF14295.6 PFH34057.1 - 1.2e-06 28.4 1.0 3.9e-06 26.7 0.4 2.3 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 PFH34057.1 - 2.5e-05 24.2 0.2 9.2e-05 22.3 0.2 2.0 1 0 0 1 1 1 1 PAN domain Glyco_hydro_16 PF00722.21 PFH34057.1 - 0.00016 21.2 0.0 0.0053 16.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 HSBP1 PF06825.12 PFH34058.1 - 1.5e-14 53.5 0.7 2.3e-14 53.0 0.7 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF4536 PF15055.6 PFH34058.1 - 0.091 13.0 1.3 0.2 11.9 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) CBM_20 PF00686.19 PFH34060.1 - 7.1e-14 51.5 0.0 1.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain DUF773 PF05600.12 PFH34062.1 - 3e-54 184.6 0.0 6e-52 177.0 0.0 2.0 1 1 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 OmpH PF03938.14 PFH34062.1 - 0.0026 18.1 2.4 0.0026 18.1 2.4 2.7 3 0 0 3 3 3 1 Outer membrane protein (OmpH-like) Med21 PF11221.8 PFH34062.1 - 0.14 12.4 2.3 0.47 10.7 2.3 1.9 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Spc7 PF08317.11 PFH34062.1 - 0.5 9.2 10.3 0.033 13.1 0.8 2.5 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF2203 PF09969.9 PFH34062.1 - 1.9 9.2 10.2 0.095 13.4 1.2 3.1 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) DUF4337 PF14235.6 PFH34062.1 - 2.6 8.1 12.8 0.95 9.6 4.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) Mod_r PF07200.13 PFH34062.1 - 7.2 6.7 8.3 0.68 10.0 1.7 2.5 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Filament PF00038.21 PFH34062.1 - 9.3 5.7 9.3 21 4.6 0.0 3.2 3 1 1 4 4 4 0 Intermediate filament protein PNP_UDP_1 PF01048.20 PFH34063.1 - 6.2e-37 127.1 0.1 7.3e-37 126.9 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily NIF PF03031.18 PFH34064.1 - 3.5e-49 166.6 0.0 4.8e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Phosphorylase PF00343.20 PFH34065.1 - 0 1015.1 0.0 0 1014.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Aminotran_1_2 PF00155.21 PFH34066.1 - 5.1e-07 29.2 0.0 0.00012 21.4 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II Peptidase_C65 PF10275.9 PFH34067.1 - 0.005 16.3 0.0 0.0064 16.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Metallophos PF00149.28 PFH34068.1 - 2.6e-41 142.4 0.1 3.2e-41 142.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PFH34068.1 - 4.9e-22 78.1 0.2 1.2e-21 76.8 0.1 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Rsm22 PF09243.10 PFH34070.1 - 8.5e-76 254.8 0.1 3e-63 213.7 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 ArgJ PF01960.18 PFH34071.1 - 0.02 13.7 0.3 0.032 13.0 0.3 1.2 1 0 0 1 1 1 0 ArgJ family Cir_N PF10197.9 PFH34071.1 - 0.61 10.3 0.0 0.61 10.3 0.0 3.9 3 1 0 3 3 3 0 N-terminal domain of CBF1 interacting co-repressor CIR TFIIA PF03153.13 PFH34071.1 - 4.8 7.1 6.3 14 5.5 6.3 1.8 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HalX PF08663.10 PFH34072.1 - 0.012 15.9 24.4 0.072 13.4 1.6 4.9 5 0 0 5 5 5 0 HalX domain Nsp1_C PF05064.13 PFH34072.1 - 0.013 15.3 1.0 0.05 13.4 1.0 1.9 1 0 0 1 1 1 0 Nsp1-like C-terminal region RACo_linker PF17650.1 PFH34072.1 - 0.035 13.9 0.9 9 6.2 0.2 2.9 2 0 0 2 2 2 0 RACo linker region Phasin PF05597.11 PFH34072.1 - 0.12 12.3 10.7 0.067 13.2 4.0 2.9 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) NPV_P10 PF05531.12 PFH34072.1 - 0.4 11.2 1.5 42 4.7 0.0 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 PFH34072.1 - 1 9.4 5.9 0.36 10.9 1.6 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF919 PF06034.11 PFH34072.1 - 2.6 7.9 5.9 14 5.6 0.5 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Exonuc_VII_L PF02601.15 PFH34072.1 - 3.2 7.2 16.5 0.32 10.5 9.9 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Golgin_A5 PF09787.9 PFH34072.1 - 3.3 7.1 11.4 1.2 8.5 6.8 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 Phage_GPO PF05929.11 PFH34072.1 - 7.5 6.1 16.8 0.25 11.0 2.4 2.9 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase EMP24_GP25L PF01105.24 PFH34074.1 - 6.2e-26 91.4 0.0 8.8e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PP2C PF00481.21 PFH34075.1 - 7.5e-46 156.8 0.0 4e-45 154.5 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PFH34075.1 - 0.013 15.1 0.5 0.026 14.2 0.5 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C IL32 PF15225.6 PFH34076.1 - 0.0032 17.8 2.1 1.4 9.4 0.3 2.7 3 0 0 3 3 3 2 Interleukin 32 YlbD_coat PF14071.6 PFH34078.1 - 0.27 11.5 1.4 4.1 7.7 0.1 2.1 1 1 1 2 2 2 0 Putative coat protein CRAL_TRIO PF00650.20 PFH34079.1 - 4.2e-25 88.3 0.0 5.7e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Apyrase PF06079.11 PFH34080.1 - 9.7e-98 327.0 0.0 1.3e-97 326.5 0.0 1.1 1 0 0 1 1 1 1 Apyrase DUF4381 PF14316.6 PFH34080.1 - 0.069 13.4 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Slu7 PF11708.8 PFH34081.1 - 1.1e-96 323.7 16.7 1.1e-96 323.7 16.7 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor ECH_1 PF00378.20 PFH34082.1 - 2.9e-40 138.2 0.0 1.7e-29 102.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PFH34082.1 - 1.1e-21 77.7 0.0 9.4e-20 71.4 0.0 2.4 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase ATP-synt_DE PF00401.20 PFH34082.1 - 7.6 6.9 10.6 1.5 9.1 4.8 2.7 2 1 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain SAG PF04092.13 PFH34083.1 - 3.1e-09 37.7 4.0 4e-09 37.3 4.0 1.2 1 0 0 1 1 1 1 SRS domain DUF1772 PF08592.11 PFH34084.1 - 0.00026 21.3 0.5 0.00049 20.4 0.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) MFS_1 PF07690.16 PFH34084.1 - 0.0073 15.3 0.2 0.0096 14.9 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-MYND PF01753.18 PFH34085.1 - 1.1e-11 44.6 12.0 2.1e-11 43.7 12.0 1.5 1 0 0 1 1 1 1 MYND finger Hen1_Lam_C PF18441.1 PFH34085.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Hen1 La-motif C-terminal domain zf-C6H2 PF15801.5 PFH34085.1 - 0.13 12.5 9.1 0.36 11.2 9.1 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 PFH34085.1 - 0.27 11.4 11.0 1.1 9.4 11.1 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Rpr2 PF04032.16 PFH34085.1 - 0.82 10.0 7.3 31 4.9 7.2 2.3 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-HIT PF04438.16 PFH34085.1 - 4.7 7.2 9.1 8.1 6.4 3.8 2.6 2 0 0 2 2 2 0 HIT zinc finger WD40 PF00400.32 PFH34086.1 - 6.8e-40 134.3 15.8 6.9e-06 26.7 0.2 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH34086.1 - 5.9e-11 42.5 0.4 0.43 10.9 0.0 5.8 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PFH34086.1 - 0.00014 21.0 0.2 0.25 10.2 0.0 3.7 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 PFH34086.1 - 0.015 15.8 1.1 0.86 10.2 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain PD40 PF07676.12 PFH34086.1 - 0.12 12.4 0.1 8.7 6.4 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat eIF2A PF08662.11 PFH34086.1 - 0.16 11.8 0.0 3.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A EMC3_TMCO1 PF01956.16 PFH34087.1 - 3.6e-16 59.4 0.0 9.1e-15 54.8 0.0 2.0 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like CHD5 PF04420.14 PFH34087.1 - 0.034 14.0 0.0 0.074 12.9 0.0 1.5 2 0 0 2 2 2 0 CHD5-like protein AP2 PF00847.20 PFH34088.1 - 2.1e-12 47.1 8.0 2.8e-06 27.5 2.3 2.8 2 0 0 2 2 2 2 AP2 domain WD40 PF00400.32 PFH34089.1 - 5.9e-08 33.2 3.3 0.014 16.2 0.3 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat AP2 PF00847.20 PFH34093.1 - 3.1e-08 33.7 0.3 8.5e-08 32.3 0.3 1.8 1 0 0 1 1 1 1 AP2 domain PHM7_cyt PF14703.6 PFH34093.1 - 0.0011 19.2 1.9 0.0027 17.9 1.9 1.6 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF3533 PF12051.8 PFH34093.1 - 0.55 9.1 3.1 1 8.2 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Phage_Mu_Gam PF07352.12 PFH34093.1 - 1.6 8.6 7.3 2.7 7.9 7.3 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein ATP-synt_F PF01990.17 PFH34094.1 - 5.8e-32 109.9 0.2 6.6e-32 109.7 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit EURL PF06937.11 PFH34095.1 - 1.3 8.4 7.7 6.4 6.1 2.6 2.4 2 0 0 2 2 2 0 EURL protein Pep_deformylase PF01327.21 PFH34096.1 - 0.16 11.5 0.4 0.24 11.0 0.4 1.3 1 0 0 1 1 1 0 Polypeptide deformylase TFIIF_alpha PF05793.12 PFH34097.1 - 0.00054 18.7 21.2 0.00068 18.4 21.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SRP-alpha_N PF04086.13 PFH34097.1 - 0.0039 17.2 13.4 0.0047 16.9 13.4 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Cwf_Cwc_15 PF04889.12 PFH34097.1 - 0.006 16.4 12.9 0.0075 16.0 12.9 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein FAM60A PF15396.6 PFH34097.1 - 0.0079 16.2 12.5 0.011 15.8 12.5 1.3 1 0 0 1 1 1 1 Protein Family FAM60A GEMIN8 PF15348.6 PFH34097.1 - 0.012 15.9 9.7 0.015 15.6 9.7 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Baculo_PP31 PF05311.11 PFH34097.1 - 0.017 14.6 15.5 0.023 14.2 15.5 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF755 PF05501.11 PFH34097.1 - 0.027 14.7 35.9 0.027 14.7 35.9 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF755) Astro_capsid_p PF12226.8 PFH34097.1 - 0.037 13.2 3.7 0.049 12.8 3.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Rrn6 PF10214.9 PFH34097.1 - 0.049 12.1 12.7 0.051 12.1 12.7 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF5427 PF10310.9 PFH34097.1 - 0.049 12.6 13.7 0.057 12.4 13.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF3807 PF12720.7 PFH34097.1 - 0.092 13.0 14.6 0.13 12.6 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2201_N PF13203.6 PFH34097.1 - 0.11 12.1 2.5 0.12 12.0 2.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Paramyxo_ncap PF00973.19 PFH34097.1 - 0.23 10.4 7.0 0.25 10.2 7.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Macoilin PF09726.9 PFH34097.1 - 0.3 9.6 12.8 0.31 9.6 12.8 1.0 1 0 0 1 1 1 0 Macoilin family DUF1168 PF06658.12 PFH34097.1 - 0.33 10.8 23.8 0.52 10.1 23.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Menin PF05053.13 PFH34097.1 - 0.56 8.5 5.7 0.62 8.4 5.7 1.0 1 0 0 1 1 1 0 Menin SAPS PF04499.15 PFH34097.1 - 0.67 8.7 9.6 0.79 8.4 9.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4692 PF15763.5 PFH34097.1 - 0.69 10.4 13.4 1.4 9.4 13.4 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) RR_TM4-6 PF06459.12 PFH34097.1 - 0.89 9.3 12.0 1 9.1 12.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4551 PF15087.6 PFH34097.1 - 1 8.2 10.0 1.1 8.0 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Eapp_C PF10238.9 PFH34097.1 - 1.1 9.3 15.5 0.61 10.2 7.6 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein CDC45 PF02724.14 PFH34097.1 - 1.4 7.1 11.1 1.7 6.8 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.8 PFH34097.1 - 1.7 7.5 14.6 1.9 7.3 14.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rtf2 PF04641.12 PFH34097.1 - 1.9 7.8 18.5 3 7.1 18.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger CobT PF06213.12 PFH34097.1 - 2.2 7.6 11.7 2.6 7.3 11.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GREB1 PF15782.5 PFH34097.1 - 2.3 5.2 11.2 2.4 5.2 11.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Apt1 PF10351.9 PFH34097.1 - 2.3 7.0 15.3 2.6 6.8 15.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NPR3 PF03666.13 PFH34097.1 - 2.3 6.9 19.2 8.4 5.1 18.9 1.8 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Afi1 PF07792.12 PFH34097.1 - 2.5 8.6 10.3 3.8 8.0 10.3 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking VIR_N PF15912.5 PFH34097.1 - 3.3 7.2 8.8 4.2 6.9 8.8 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DUF913 PF06025.12 PFH34097.1 - 3.5 6.5 7.7 3.9 6.3 7.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 PFH34097.1 - 3.6 6.3 13.1 4.5 5.9 13.1 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 PFH34097.1 - 4.1 6.5 8.6 4.8 6.3 8.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 PFH34097.1 - 5 6.8 7.6 6.2 6.5 7.6 1.2 1 0 0 1 1 1 0 Connexin PPL5 PF18168.1 PFH34097.1 - 7.4 5.8 10.6 9.3 5.4 10.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 ALMT PF11744.8 PFH34097.1 - 7.7 5.2 7.6 8.7 5.0 7.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MCM_bind PF09739.9 PFH34097.1 - 8.8 4.6 12.9 12 4.2 12.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF5423 PF17461.2 PFH34099.1 - 2.2 7.1 11.6 3.3 6.5 11.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) SOG2 PF10428.9 PFH34099.1 - 3.8 6.6 13.5 5.7 6.0 13.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein U3snoRNP10 PF12397.8 PFH34100.1 - 1.2e-16 61.1 1.8 6.9e-16 58.6 1.8 2.5 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 10 HD PF01966.22 PFH34102.1 - 9.6e-10 38.7 0.0 8.8e-08 32.4 0.0 2.5 2 0 0 2 2 2 2 HD domain Auxin_repressed PF05564.12 PFH34102.1 - 6.4 7.5 12.9 0.95 10.2 0.3 3.9 3 0 0 3 3 3 0 Dormancy/auxin associated protein Ion_trans PF00520.31 PFH34105.1 - 9.4e-27 93.8 16.3 3.5e-22 78.8 3.9 2.5 2 0 0 2 2 2 2 Ion transport protein PRIMA1 PF16101.5 PFH34105.1 - 0.0053 16.8 0.1 0.0053 16.8 0.1 4.0 4 0 0 4 4 4 1 Proline-rich membrane anchor 1 UCH PF00443.29 PFH34106.1 - 2.4e-39 135.4 0.0 3.3e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PFH34106.1 - 1.6e-05 24.7 0.6 0.015 14.9 0.0 2.5 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase FTCD_C PF04961.12 PFH34106.1 - 0.03 14.1 0.4 0.11 12.3 0.4 2.0 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Ufm1 PF03671.14 PFH34108.1 - 7.7e-39 131.7 0.2 1.4e-38 130.8 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein zf_CCCH_4 PF18345.1 PFH34108.1 - 0.00024 21.0 0.8 0.00024 21.0 0.8 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 PFH34108.1 - 0.018 14.8 0.5 0.047 13.5 0.5 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 PFH34108.1 - 0.035 14.0 0.8 0.097 12.6 0.8 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SURF1 PF02104.15 PFH34110.1 - 1.9e-23 83.6 0.0 5.2e-14 52.9 0.0 2.8 2 1 0 2 2 2 2 SURF1 family DUF5516 PF17637.2 PFH34110.1 - 0.9 9.3 3.7 1.7 8.5 3.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5516) PWI PF01480.17 PFH34112.1 - 1.2e-25 89.6 0.0 1.8e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 PWI domain CALM_bind PF16025.5 PFH34112.1 - 0.002 18.6 1.3 0.0058 17.1 1.3 1.7 1 0 0 1 1 1 1 Calcium-dependent calmodulin binding Dehydrin PF00257.19 PFH34112.1 - 0.0035 17.9 2.2 0.0047 17.5 1.3 1.6 1 1 0 1 1 1 1 Dehydrin UPF0239 PF06783.11 PFH34113.1 - 0.056 13.6 0.1 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) Cwf_Cwc_15 PF04889.12 PFH34114.1 - 2.8 7.6 6.8 12 5.5 2.2 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TauE PF01925.19 PFH34116.1 - 1.1e-19 71.1 43.3 8.6e-11 41.9 8.0 3.2 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE K-box PF01486.17 PFH34117.1 - 0.11 12.7 7.2 0.018 15.2 1.7 2.5 1 1 1 2 2 2 0 K-box region CheZ PF04344.13 PFH34117.1 - 0.82 9.6 7.2 0.38 10.6 3.3 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DnaJ_C PF01556.18 PFH34118.1 - 3e-38 131.2 0.2 4.3e-38 130.7 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PFH34118.1 - 9.9e-24 83.3 1.0 1.9e-23 82.3 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 PFH34118.1 - 8.7e-15 54.8 15.1 1.7e-14 53.9 15.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 PFH34118.1 - 0.035 14.1 14.6 0.55 10.2 4.7 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 PFH34118.1 - 0.52 10.4 8.3 1.5 8.9 0.4 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 PFH34118.1 - 3.9 7.7 6.9 0.82 9.8 0.7 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 BTB PF00651.31 PFH34120.1 - 2.5e-07 30.9 0.0 5.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Nop25 PF09805.9 PFH34120.1 - 4.2 7.8 21.8 0.89 10.0 5.5 2.7 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) EF-hand_7 PF13499.6 PFH34124.1 - 9e-05 22.9 0.0 0.00024 21.5 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 PFH34124.1 - 0.00067 19.5 0.6 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair PTPLA PF04387.14 PFH34126.1 - 1.7e-43 148.2 12.6 4.9e-43 146.7 12.6 1.7 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA cNMP_binding PF00027.29 PFH34127.1 - 2.5e-41 139.7 0.2 7e-20 70.9 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Syntaxin_2 PF14523.6 PFH34127.1 - 0.0044 17.4 2.1 0.011 16.0 1.5 2.0 2 0 0 2 2 2 1 Syntaxin-like protein FlxA PF14282.6 PFH34127.1 - 0.007 16.3 1.3 0.015 15.3 1.3 1.5 1 0 0 1 1 1 1 FlxA-like protein RIIa PF02197.17 PFH34127.1 - 0.0074 15.9 0.1 0.019 14.6 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cwf_Cwc_15 PF04889.12 PFH34127.1 - 0.027 14.2 8.3 0.053 13.3 8.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PfkB PF00294.24 PFH34127.1 - 0.064 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 pfkB family carbohydrate kinase FAM176 PF14851.6 PFH34127.1 - 0.76 9.4 4.8 1.4 8.6 4.8 1.4 1 0 0 1 1 1 0 FAM176 family Metallophos PF00149.28 PFH34128.1 - 3.3e-33 115.9 0.0 7.1e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase V-SNARE_C PF12352.8 PFH34129.1 - 1.5e-08 34.8 0.3 3.6e-08 33.6 0.3 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 PFH34129.1 - 1.2e-07 32.0 1.7 5.5e-05 23.5 0.1 2.8 3 0 0 3 3 3 2 Vesicle transport v-SNARE protein N-terminus HAUS-augmin3 PF14932.6 PFH34129.1 - 0.31 10.6 0.1 0.31 10.6 0.1 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 KxDL PF10241.9 PFH34129.1 - 3 8.2 5.6 17 5.8 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein DSPc PF00782.20 PFH34130.1 - 3.8e-15 55.9 0.0 7.4e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pkinase PF00069.25 PFH34131.1 - 9.3e-63 212.0 0.0 1.6e-62 211.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 PFH34131.1 - 1.1e-61 204.9 1.3 9.6e-18 64.0 0.0 4.8 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 PFH34131.1 - 1.4e-31 109.7 0.0 2.4e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH34131.1 - 1.4e-06 27.9 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Cupin_2 PF07883.11 PFH34131.1 - 0.00055 19.6 0.5 11 5.8 0.0 4.2 4 0 0 4 4 4 2 Cupin domain Kdo PF06293.14 PFH34131.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH34131.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PFH34131.1 - 0.058 12.3 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FXR_C3 PF16097.5 PFH34131.1 - 5.3 7.8 5.5 1.5 9.6 0.6 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 Aldedh PF00171.22 PFH34132.1 - 8.3e-128 426.8 0.0 1e-127 426.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family tRNA_m1G_MT PF01746.21 PFH34134.1 - 3.5e-17 62.7 0.0 1.1e-15 57.9 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Prp18 PF02840.15 PFH34135.1 - 0.00012 22.1 0.1 0.00023 21.2 0.1 1.4 1 0 0 1 1 1 1 Prp18 domain SRA1 PF07304.11 PFH34135.1 - 0.0056 16.5 0.0 0.0056 16.5 0.0 2.7 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) ANAPC4_WD40 PF12894.7 PFH34135.1 - 0.04 14.2 0.0 9.7 6.6 0.0 2.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PFH34135.1 - 3.1 8.8 17.5 5.3 8.1 0.2 5.5 5 1 0 5 5 5 0 WD domain, G-beta repeat Mpp10 PF04006.12 PFH34136.1 - 1.1e-59 202.6 96.9 1.4e-36 126.2 12.8 2.8 2 1 0 2 2 2 2 Mpp10 protein Fibrillarin PF01269.17 PFH34137.1 - 1.6e-106 354.5 0.0 2e-106 354.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 PFH34137.1 - 0.00016 21.5 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DREV PF05219.12 PFH34137.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltr_RsmB-F PF01189.17 PFH34137.1 - 0.072 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 PFH34137.1 - 0.13 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FoP_duplication PF13865.6 PFH34137.1 - 8 7.1 21.6 16 6.2 21.6 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf-C2H2 PF00096.26 PFH34138.1 - 1.3e-29 101.0 64.1 0.00021 21.6 0.8 9.7 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PFH34138.1 - 1.5e-21 75.2 59.8 0.0026 18.4 1.2 9.5 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PFH34138.1 - 7.8e-12 45.1 62.4 5.8e-07 29.7 2.4 10.7 10 2 1 11 11 10 6 Zinc-finger double domain zf-C2H2_6 PF13912.6 PFH34138.1 - 4e-10 39.4 37.5 0.0063 16.5 0.1 7.5 7 0 0 7 7 6 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PFH34138.1 - 9.4e-08 32.3 24.3 0.0047 17.2 0.9 4.9 4 1 0 4 4 4 3 C2H2-type zinc ribbon zf-met PF12874.7 PFH34138.1 - 3.7e-05 23.9 23.1 0.59 10.6 0.0 8.0 8 0 0 8 8 8 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PFH34138.1 - 8.1e-05 22.8 29.1 0.24 11.7 0.1 7.9 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 PFH34138.1 - 0.00014 21.8 13.1 0.55 10.3 0.3 5.2 4 1 1 5 5 5 2 CpXC protein IBR PF01485.21 PFH34138.1 - 0.00069 19.8 30.0 0.036 14.3 0.1 5.4 4 2 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C2H2_3rep PF18868.1 PFH34138.1 - 0.0019 18.9 23.4 1.7 9.4 0.4 5.6 3 3 2 5 5 5 3 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 PFH34138.1 - 0.014 15.7 30.4 0.016 15.5 0.3 5.5 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 PFH34138.1 - 0.02 14.5 17.0 2.3 7.9 2.8 4.9 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain GAGA PF09237.11 PFH34138.1 - 0.036 13.9 1.0 0.036 13.9 1.0 6.1 4 3 3 7 7 7 0 GAGA factor Zn-ribbon_8 PF09723.10 PFH34138.1 - 0.037 14.1 22.6 0.28 11.3 2.3 5.1 4 1 0 4 4 4 0 Zinc ribbon domain DZR PF12773.7 PFH34138.1 - 0.043 13.9 0.6 0.043 13.9 0.6 5.0 5 1 0 5 5 5 0 Double zinc ribbon zf_UBZ PF18439.1 PFH34138.1 - 0.047 13.3 16.7 2 8.1 0.1 6.2 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger ADK_lid PF05191.14 PFH34138.1 - 0.26 11.3 14.0 0.41 10.7 0.7 4.6 4 1 1 5 5 4 0 Adenylate kinase, active site lid OSTMP1 PF09777.9 PFH34138.1 - 0.54 9.6 4.1 4 6.8 0.7 2.4 2 1 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor Actin_micro PF17003.5 PFH34138.1 - 1.1 8.4 13.0 11 5.1 0.3 4.4 3 1 1 5 5 5 0 Putative actin-like family HypA PF01155.19 PFH34138.1 - 5.9 7.0 14.7 1 9.4 0.6 3.7 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ACAS_N PF16177.5 PFH34140.1 - 0.11 12.4 0.0 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus ThiF PF00899.21 PFH34142.1 - 1.8e-54 184.7 0.1 6.5e-26 91.2 0.0 2.3 2 0 0 2 2 2 2 ThiF family UAE_UbL PF14732.6 PFH34142.1 - 6.4e-13 49.1 0.0 1.4e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 PFH34142.1 - 4.4e-11 43.2 0.8 2e-05 24.6 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 PFH34142.1 - 0.0043 17.1 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 PFH34142.1 - 0.015 15.8 1.3 0.083 13.3 0.0 2.9 3 2 0 3 3 3 0 Putative NAD(P)-binding adh_short PF00106.25 PFH34142.1 - 0.12 11.9 0.6 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 PFH34142.1 - 0.12 12.6 2.4 32 4.8 0.0 3.5 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain WD40 PF00400.32 PFH34143.1 - 6.4e-10 39.5 9.6 0.0018 19.1 0.0 5.4 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-HC5HC2H_2 PF13832.6 PFH34143.1 - 2.8e-07 30.7 1.8 6e-07 29.6 1.8 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PFH34143.1 - 2.3e-06 27.8 2.5 4.7e-06 26.8 2.5 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Bromodomain PF00439.25 PFH34143.1 - 1.8e-05 24.7 0.0 3.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain UIM PF02809.20 PFH34143.1 - 0.069 13.1 0.0 0.32 11.0 0.0 2.3 1 0 0 1 1 1 0 Ubiquitin interaction motif PHD PF00628.29 PFH34143.1 - 0.23 11.4 3.4 0.33 10.9 1.8 2.1 2 0 0 2 2 2 0 PHD-finger ANAPC4_WD40 PF12894.7 PFH34143.1 - 0.24 11.7 0.1 4.6 7.6 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain LRR_6 PF13516.6 PFH34144.1 - 1e-05 25.1 4.0 0.12 12.5 0.1 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 PFH34144.1 - 0.00022 21.6 0.8 0.44 11.1 0.2 2.9 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH34144.1 - 0.0066 16.2 0.1 9 6.1 0.0 3.4 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 PFH34144.1 - 1.2 10.0 4.9 57 4.8 0.2 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat SET PF00856.28 PFH34145.1 - 1.6e-19 71.0 0.3 7.4e-19 68.7 0.0 2.4 2 0 0 2 2 2 1 SET domain FUN14 PF04930.15 PFH34146.1 - 3.8e-21 75.3 0.2 5.1e-21 74.9 0.2 1.2 1 0 0 1 1 1 1 FUN14 family Dockerin_1 PF00404.18 PFH34146.1 - 0.00085 19.5 0.1 0.0014 18.8 0.1 1.3 1 0 0 1 1 1 1 Dockerin type I domain Peptidase_C97 PF05903.14 PFH34147.1 - 3.2e-42 143.9 0.0 4.8e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.10 PFH34147.1 - 3.2e-14 52.6 0.2 1.9e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 PUB domain UBA PF00627.31 PFH34147.1 - 8.5e-08 32.0 0.6 8.2e-06 25.6 0.4 2.5 2 0 0 2 2 2 1 UBA/TS-N domain CUE PF02845.16 PFH34147.1 - 0.063 13.0 0.2 0.25 11.1 0.2 2.0 2 0 0 2 2 2 0 CUE domain HOIP-UBA PF16678.5 PFH34147.1 - 0.14 12.1 0.3 0.94 9.5 0.1 2.1 2 0 0 2 2 2 0 HOIP UBA domain pair CAP_N PF01213.19 PFH34147.1 - 2.3 7.6 4.9 4.4 6.7 0.5 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal FAM176 PF14851.6 PFH34148.1 - 0.21 11.2 2.0 0.47 10.1 2.0 1.5 1 0 0 1 1 1 0 FAM176 family GCIP PF13324.6 PFH34148.1 - 0.48 10.0 4.8 0.84 9.2 4.8 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting PBP1_TM PF14812.6 PFH34148.1 - 0.49 10.8 8.5 0.29 11.5 5.5 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 PFH34148.1 - 0.69 9.6 11.1 1.1 8.9 11.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 PFH34148.1 - 3.2 7.8 6.0 5.8 6.9 6.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF89 PF01937.19 PFH34150.1 - 0.19 10.6 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF89 HSP70 PF00012.20 PFH34151.1 - 6.7e-258 856.8 15.0 7.8e-258 856.6 15.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PFH34151.1 - 2.1e-21 76.1 0.7 2.1e-21 76.1 0.7 2.6 3 0 0 3 3 3 1 MreB/Mbl protein Radial_spoke_3 PF06098.11 PFH34151.1 - 0.00064 19.1 3.1 0.00064 19.1 3.1 1.9 2 0 0 2 2 2 1 Radial spoke protein 3 FGGY_C PF02782.16 PFH34151.1 - 0.001 18.8 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 PFH34151.1 - 0.0018 18.7 5.2 0.46 10.9 0.1 3.8 3 2 0 3 3 3 2 Cell division protein FtsA DIOX_N PF14226.6 PFH34151.1 - 0.24 12.1 2.9 0.24 12.2 0.6 2.1 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal AAA_11 PF13086.6 PFH34151.1 - 0.27 11.0 3.2 1.3 8.8 0.6 2.3 2 0 0 2 2 2 0 AAA domain Effector_1 PF04518.12 PFH34151.1 - 2 7.4 6.4 0.36 9.9 0.8 2.1 2 0 0 2 2 2 0 Effector from type III secretion system Lactamase_B PF00753.27 PFH34152.1 - 0.043 13.8 1.9 0.25 11.3 0.9 2.3 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Drf_DAD PF06345.11 PFH34153.1 - 0.043 13.9 0.6 0.29 11.2 0.6 2.6 1 0 0 1 1 1 0 DRF Autoregulatory Domain Mago-bind PF09282.10 PFH34154.1 - 1.1e-14 54.0 4.9 1.1e-14 54.0 4.9 1.8 2 0 0 2 2 2 1 Mago binding ABC_tran_CTD PF16326.5 PFH34154.1 - 4.8 7.5 13.9 0.5 10.6 9.1 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain Enkurin PF13864.6 PFH34154.1 - 6.6 7.2 15.4 4.4 7.8 12.7 2.0 2 1 0 2 2 2 0 Calmodulin-binding ADH_zinc_N PF00107.26 PFH34156.1 - 5.8e-25 87.8 0.1 1.4e-24 86.5 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PFH34156.1 - 2e-18 66.3 2.9 4.6e-18 65.1 2.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 PFH34156.1 - 0.0056 16.0 2.0 0.04 13.2 0.1 2.1 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 PFH34156.1 - 0.011 15.3 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 PFH34156.1 - 0.018 16.1 0.0 0.041 14.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Fe_dep_repr_C PF02742.15 PFH34157.1 - 0.14 12.3 0.2 0.46 10.6 0.2 1.8 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Exo_endo_phos PF03372.23 PFH34158.1 - 1.1e-07 31.6 0.1 3.8e-07 29.9 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SUR7 PF06687.12 PFH34160.1 - 0.00075 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 SUR7/PalI family Phage_holin_3_6 PF07332.11 PFH34160.1 - 0.84 9.7 3.8 1.7 8.7 3.8 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TMF_TATA_bd PF12325.8 PFH34161.1 - 0.001 19.3 2.7 0.0017 18.6 2.7 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding KLRAQ PF10205.9 PFH34161.1 - 0.0062 16.8 5.9 0.012 15.8 5.9 1.5 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein Ax_dynein_light PF10211.9 PFH34161.1 - 0.066 13.2 5.4 0.091 12.7 5.4 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain APG6_N PF17675.1 PFH34161.1 - 0.066 13.7 4.0 0.08 13.5 4.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 PFH34161.1 - 0.077 13.2 6.2 0.17 12.1 6.2 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FliJ PF02050.16 PFH34161.1 - 0.21 11.8 12.9 0.37 11.0 12.9 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein VSG_B PF13206.6 PFH34161.1 - 0.27 10.5 5.3 0.33 10.1 5.3 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain betaPIX_CC PF16523.5 PFH34161.1 - 0.94 9.3 9.8 1.5 8.7 9.8 1.3 1 0 0 1 1 1 0 betaPIX coiled coil DUF789 PF05623.12 PFH34163.1 - 2.7e-17 63.4 6.1 1.7e-16 60.8 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF789) CAF1C_H4-bd PF12265.8 PFH34164.1 - 1.4e-15 57.3 0.1 4.7e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 PFH34164.1 - 3.2e-07 30.9 17.8 0.0014 19.4 1.2 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH34164.1 - 0.00053 20.2 1.0 0.092 13.1 0.1 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain GYF PF02213.16 PFH34165.1 - 0.00038 20.1 0.0 0.00085 18.9 0.0 1.6 1 0 0 1 1 1 1 GYF domain BACK PF07707.15 PFH34165.1 - 0.012 15.7 0.0 0.69 10.0 0.0 2.6 2 0 0 2 2 2 0 BTB And C-terminal Kelch CTU2 PF10288.9 PFH34167.1 - 1.3e-05 25.4 0.4 1.3e-05 25.4 0.4 3.8 3 2 1 4 4 4 1 Cytoplasmic tRNA 2-thiolation protein 2 PGC7_Stella PF15549.6 PFH34167.1 - 0.05 13.6 2.0 0.2 11.6 1.9 2.1 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain GRAM PF02893.20 PFH34168.1 - 5.4e-12 45.6 1.2 9.9e-12 44.8 1.2 1.4 1 0 0 1 1 1 1 GRAM domain SH3_2 PF07653.17 PFH34168.1 - 0.00089 18.9 0.4 0.023 14.4 0.2 2.6 2 0 0 2 2 2 1 Variant SH3 domain VASt PF16016.5 PFH34168.1 - 0.0013 19.1 0.0 0.0033 17.8 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Ras PF00071.22 PFH34169.1 - 7.3e-56 188.2 0.0 9.6e-56 187.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH34169.1 - 4.5e-28 97.9 0.0 8.9e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH34169.1 - 5.6e-10 39.0 0.0 7.6e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PFH34169.1 - 0.02 14.4 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PFH34169.1 - 0.051 13.7 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PFH34169.1 - 0.2 11.0 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_L14 PF00238.19 PFH34172.1 - 5.7e-31 107.1 0.0 7.8e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e E1-E2_ATPase PF00122.20 PFH34173.1 - 5.3e-39 133.6 0.0 4.5e-38 130.6 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 PFH34173.1 - 3.4e-33 114.9 0.2 3.4e-33 114.9 0.2 3.8 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 PFH34173.1 - 2e-18 67.4 0.0 8.1e-10 39.3 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PFH34173.1 - 8.6e-14 51.4 0.0 1.6e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PFH34173.1 - 1.6e-06 27.7 0.0 6.4e-06 25.8 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PFH34173.1 - 0.00012 22.0 1.1 0.00028 20.7 0.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Thioredoxin_8 PF13905.6 PFH34174.1 - 3.7e-46 155.4 0.0 1.1e-27 96.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 PFH34174.1 - 2.5e-09 37.0 0.0 1.5e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Redoxin Thioredoxin_2 PF13098.6 PFH34174.1 - 5.5e-08 33.2 0.0 4.2e-05 23.9 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 PFH34174.1 - 9.2e-07 28.8 0.0 5e-05 23.2 0.1 2.7 2 1 1 3 3 3 1 Thioredoxin AhpC-TSA PF00578.21 PFH34174.1 - 6.3e-06 26.1 0.0 1.9e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family SCO1-SenC PF02630.14 PFH34174.1 - 0.0018 18.2 0.0 0.0078 16.1 0.0 1.9 2 0 0 2 2 2 1 SCO1/SenC Thioredoxin_7 PF13899.6 PFH34174.1 - 0.0029 17.8 0.0 0.014 15.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Glutaredoxin PF00462.24 PFH34174.1 - 0.047 13.9 1.4 0.93 9.8 1.0 3.4 3 1 0 3 3 3 0 Glutaredoxin Thioredoxin_9 PF14595.6 PFH34174.1 - 0.086 12.6 0.2 0.43 10.4 0.0 2.2 2 1 1 3 3 3 0 Thioredoxin PAS_4 PF08448.10 PFH34174.1 - 0.19 12.0 0.9 1.5 9.1 0.1 2.8 3 0 0 3 3 3 0 PAS fold Trs65 PF12735.7 PFH34175.1 - 5.9e-05 22.6 0.0 0.0052 16.2 0.0 2.3 2 0 0 2 2 2 2 TRAPP trafficking subunit Trs65 Nepo_coat_C PF03688.14 PFH34179.1 - 0.0035 17.2 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 Nepovirus coat protein, C-terminal domain GRP PF07172.11 PFH34180.1 - 0.21 12.3 0.1 0.21 12.3 0.1 3.4 3 0 0 3 3 3 0 Glycine rich protein family Cohesin_HEAT PF12765.7 PFH34182.1 - 0.0035 17.6 2.3 2.3 8.6 0.1 2.8 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 PFH34182.1 - 0.97 9.9 10.6 3.5 8.1 0.1 4.8 5 0 0 5 5 5 0 HEAT repeat Metallophos PF00149.28 PFH34183.1 - 5e-35 121.9 0.1 9.5e-35 121.0 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 PFH34183.1 - 3.1e-19 69.0 0.1 6.7e-19 68.0 0.1 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 PFH34183.1 - 4.6e-12 45.2 6.1 1.2e-05 24.9 1.4 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PFH34183.1 - 4.9e-11 41.9 5.0 5.7e-05 22.9 1.6 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 PFH34183.1 - 3.1e-05 23.8 0.5 0.078 13.2 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 PFH34183.1 - 0.00084 19.5 0.5 0.0051 17.1 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PFH34183.1 - 0.008 16.1 0.1 0.38 10.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 PFH34183.1 - 0.011 15.9 0.0 0.041 14.0 0.0 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat Cdh1_DBD_1 PF18196.1 PFH34183.1 - 0.17 12.2 1.6 1.5 9.2 0.5 2.5 2 1 1 3 3 3 0 Chromodomain helicase DNA-binding domain 1 FlgN PF05130.12 PFH34184.1 - 0.043 14.3 0.0 1.2 9.7 0.0 2.6 2 0 0 2 2 2 0 FlgN protein DUF1180 PF06679.12 PFH34184.1 - 0.087 13.2 3.2 0.11 12.9 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Tim17 PF02466.19 PFH34187.1 - 6.4e-23 81.3 3.8 6.4e-23 81.3 3.8 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Macoilin PF09726.9 PFH34187.1 - 6.4 5.2 7.4 8.1 4.9 7.4 1.1 1 0 0 1 1 1 0 Macoilin family Chorion_2 PF03964.15 PFH34187.1 - 7.1 7.5 18.9 13 6.7 18.9 1.4 1 1 0 1 1 1 0 Chorion family 2 DNA_topoisoIV PF00521.20 PFH34188.1 - 2e-127 425.7 0.0 3.2e-127 425.0 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 PFH34188.1 - 5.6e-49 165.7 3.6 5.6e-49 165.7 3.6 1.9 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 PFH34188.1 - 4.1e-22 78.5 1.1 9.6e-22 77.3 1.1 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 PFH34188.1 - 1.1e-09 38.8 0.0 2.7e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 PFH34188.1 - 3.2e-07 30.5 0.0 9.3e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Sec15 PF04091.12 PFH34189.1 - 0.079 12.4 0.5 0.086 12.2 0.5 1.1 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like MEDS PF14417.6 PFH34191.1 - 0.14 11.9 0.5 0.31 10.9 0.5 1.5 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain TFIIS_C PF01096.18 PFH34192.1 - 2.1e-18 65.9 8.8 2.1e-18 65.9 8.8 3.5 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 PFH34192.1 - 1.7e-09 37.4 1.4 1.7e-09 37.4 1.4 2.5 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 PFH34192.1 - 0.00034 20.5 14.3 0.062 13.3 1.7 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain DpnI PF06044.12 PFH34192.1 - 0.084 12.5 0.2 0.084 12.5 0.2 2.1 2 0 0 2 2 2 0 Dam-replacing family zinc_ribbon_4 PF13717.6 PFH34192.1 - 0.23 11.4 0.3 0.23 11.4 0.3 3.9 4 0 0 4 4 4 0 zinc-ribbon domain DUF3716 PF12511.8 PFH34192.1 - 1.3 9.2 11.5 0.13 12.3 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) DUF2387 PF09526.10 PFH34192.1 - 2.3 8.4 10.5 3.3 7.9 2.5 2.2 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Baculo_LEF5_C PF11792.8 PFH34192.1 - 3.1 7.5 9.9 0.14 11.9 3.9 1.8 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Hira PF07569.11 PFH34193.1 - 0.0006 19.6 0.2 0.0015 18.3 0.2 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 PFH34193.1 - 0.024 15.5 10.6 2.8 9.0 0.0 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat AAA PF00004.29 PFH34194.1 - 2.4e-05 24.8 0.0 0.00036 21.0 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PseudoU_synth_2 PF00849.22 PFH34195.1 - 1.5e-26 93.4 0.0 3.9e-26 92.1 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase HA2 PF04408.23 PFH34196.1 - 7.5e-26 90.5 0.0 2.7e-25 88.7 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PFH34196.1 - 2.2e-23 82.4 0.1 7e-23 80.8 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PFH34196.1 - 2.1e-10 40.9 0.0 5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PFH34196.1 - 2.1e-06 28.0 0.0 8.4e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 PFH34196.1 - 3.9e-06 26.7 0.0 8.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase S1 PF00575.23 PFH34196.1 - 1.5e-05 25.2 0.2 3.9e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain AAA_19 PF13245.6 PFH34196.1 - 0.00028 21.2 0.1 0.00086 19.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PFH34196.1 - 0.0003 20.6 0.0 0.00089 19.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 PFH34196.1 - 0.0022 18.5 0.4 3 8.4 0.0 3.7 3 0 0 3 3 3 1 ABC transporter T2SSE PF00437.20 PFH34196.1 - 0.0079 15.3 0.1 0.018 14.1 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 PFH34196.1 - 0.035 13.3 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Microtub_bd PF16796.5 PFH34196.1 - 0.038 13.9 0.0 0.98 9.4 0.0 2.5 2 0 0 2 2 2 0 Microtubule binding PhoH PF02562.16 PFH34196.1 - 0.038 13.5 0.1 0.14 11.6 0.1 1.9 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 PFH34196.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF3446 PF11928.8 PFH34196.1 - 0.69 10.3 11.0 9 6.7 9.8 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF755 PF05501.11 PFH34196.1 - 1.5 9.1 13.2 3.7 7.9 13.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.9 PFH34196.1 - 2.2 7.9 12.4 5.4 6.6 12.4 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 PFH34196.1 - 3.2 8.5 10.9 0.41 11.4 6.2 1.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein Sec7 PF01369.20 PFH34197.1 - 1e-44 152.4 0.0 1.5e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain RabGAP-TBC PF00566.18 PFH34197.1 - 1.3e-29 103.4 0.0 2.1e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain AAA PF00004.29 PFH34198.1 - 2.5e-35 121.8 0.0 6.3e-35 120.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PFH34198.1 - 1.1e-05 25.3 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 PFH34198.1 - 4.6e-05 23.1 0.7 0.018 14.7 0.2 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 PFH34198.1 - 0.00011 22.2 0.0 0.00057 19.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) CENP-F_leu_zip PF10473.9 PFH34198.1 - 0.0002 21.4 7.2 0.00036 20.6 7.2 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.6 PFH34198.1 - 0.00045 20.3 9.6 0.00045 20.3 9.6 2.1 1 1 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion AAA_2 PF07724.14 PFH34198.1 - 0.0012 19.0 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 PFH34198.1 - 0.0022 18.4 0.0 0.0022 18.4 0.0 3.6 3 3 1 4 4 1 1 AAA ATPase domain AAA_22 PF13401.6 PFH34198.1 - 0.0023 18.2 4.8 0.0046 17.2 0.3 2.8 2 1 0 2 2 1 1 AAA domain AAA_lid_3 PF17862.1 PFH34198.1 - 0.0038 17.0 0.0 0.0038 17.0 0.0 3.1 3 0 0 3 3 3 1 AAA+ lid domain XRCC4 PF06632.12 PFH34198.1 - 0.0051 15.7 2.7 0.0096 14.8 2.7 1.3 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Fungal_TACC PF12709.7 PFH34198.1 - 0.012 16.1 1.5 0.03 14.8 1.5 1.6 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins AAA_33 PF13671.6 PFH34198.1 - 0.013 15.6 0.0 0.042 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PFH34198.1 - 0.018 15.6 0.0 0.052 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 PFH34198.1 - 0.018 15.1 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase TIP49 PF06068.13 PFH34198.1 - 0.019 14.2 0.0 0.019 14.2 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain Vps4_C PF09336.10 PFH34198.1 - 0.028 14.4 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_24 PF13479.6 PFH34198.1 - 0.032 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 PFH34198.1 - 0.042 13.2 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 PFH34198.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain TPR_MLP1_2 PF07926.12 PFH34198.1 - 0.063 13.3 7.3 0.17 12.0 7.3 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_23 PF13476.6 PFH34198.1 - 0.098 13.1 0.9 18 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PFH34198.1 - 0.1 12.8 0.0 0.1 12.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain HALZ PF02183.18 PFH34198.1 - 0.12 12.6 1.4 0.31 11.3 1.4 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper IstB_IS21 PF01695.17 PFH34198.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein STAT_alpha PF01017.20 PFH34198.1 - 0.15 12.0 3.2 0.24 11.3 3.2 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain TsaE PF02367.17 PFH34198.1 - 0.19 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE YabA PF06156.13 PFH34198.1 - 0.25 12.0 1.5 0.54 10.9 1.5 1.5 1 0 0 1 1 1 0 Initiation control protein YabA NRBF2 PF08961.10 PFH34198.1 - 0.3 10.7 2.9 0.92 9.1 2.9 1.8 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator ERM PF00769.19 PFH34198.1 - 0.37 10.6 15.2 0.59 9.9 15.2 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family GIT_CC PF16559.5 PFH34198.1 - 0.51 10.2 3.1 0.96 9.4 3.1 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3450 PF11932.8 PFH34198.1 - 0.8 9.0 8.1 1.5 8.1 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1640 PF07798.11 PFH34198.1 - 1.8 8.5 5.8 3.3 7.7 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) AAA_11 PF13086.6 PFH34198.1 - 4 7.1 7.8 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Uso1_p115_C PF04871.13 PFH34198.1 - 5.1 7.5 9.3 16 5.8 9.3 1.8 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2968 PF11180.8 PFH34198.1 - 6.8 6.3 11.3 12 5.4 11.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DivIC PF04977.15 PFH34198.1 - 7.9 6.3 9.4 0.21 11.4 2.6 1.9 2 0 0 2 2 1 0 Septum formation initiator CcmD PF04995.14 PFH34199.1 - 0.00073 19.6 4.5 0.0046 17.0 1.4 2.6 2 0 0 2 2 2 1 Heme exporter protein D (CcmD) DUF1206 PF06724.11 PFH34199.1 - 0.0038 17.3 5.6 0.0067 16.5 5.6 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1206) PIRT PF15099.6 PFH34199.1 - 0.028 14.0 0.0 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Herpes_UL56 PF04534.12 PFH34199.1 - 0.061 12.8 3.2 0.11 12.0 3.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein TMEM171 PF15471.6 PFH34199.1 - 0.11 11.5 0.1 0.26 10.2 0.0 1.6 2 0 0 2 2 2 0 Transmembrane protein family 171 Trp_oprn_chp PF09534.10 PFH34199.1 - 0.81 9.5 6.9 4.2 7.1 7.2 1.8 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Neur_chan_memb PF02932.16 PFH34201.1 - 2.7 8.0 5.1 11 6.0 5.1 1.8 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0029 PF01205.19 PFH34202.1 - 3.3e-33 114.2 0.7 8.8e-33 112.8 0.7 1.8 1 1 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 PFH34202.1 - 0.011 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain UPRTase PF14681.6 PFH34203.1 - 2.4e-79 265.6 0.0 2.9e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 PFH34203.1 - 0.00091 18.8 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF4821 PF16092.5 PFH34205.1 - 5.9e-44 150.7 0.1 5.8e-39 134.3 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4821) DUF2183 PF09949.9 PFH34207.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Methyltransf_16 PF10294.9 PFH34208.1 - 1.8e-11 44.1 0.0 0.00018 21.3 0.2 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_25 PF13649.6 PFH34208.1 - 0.00011 22.8 0.0 0.0045 17.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PFH34208.1 - 0.00027 20.5 0.1 0.00049 19.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 PFH34208.1 - 0.001 18.9 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PFH34208.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 KH_6 PF15985.5 PFH34209.1 - 1e-10 41.8 0.0 2.1e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 KH domain TPR_19 PF14559.6 PFH34211.1 - 3.3e-12 46.7 1.3 3.3e-12 46.7 1.3 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PFH34211.1 - 3.3e-09 36.7 2.3 0.00063 19.8 0.0 2.5 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 PFH34211.1 - 8.1e-09 34.9 1.3 0.04 13.8 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PFH34211.1 - 1.3e-07 31.1 10.5 0.041 14.0 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 PFH34211.1 - 1.9e-05 24.3 0.0 0.00061 19.4 0.0 2.7 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.6 PFH34211.1 - 0.0006 20.4 5.2 0.011 16.4 3.1 4.6 3 2 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH34211.1 - 0.0012 19.1 0.8 0.0038 17.4 0.7 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PFH34211.1 - 0.0017 18.9 3.4 0.0022 18.5 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 PFH34211.1 - 0.0076 16.9 2.1 0.0076 16.9 2.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 PFH34211.1 - 0.018 15.0 0.4 0.17 12.0 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PFH34211.1 - 0.051 13.8 0.2 1.4 9.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 PFH34211.1 - 0.12 12.9 3.5 0.19 12.2 0.5 2.6 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation Mcl1_mid PF12341.8 PFH34213.1 - 7.4e-31 107.6 0.0 5.1e-27 95.0 0.0 2.4 2 0 0 2 2 2 2 Minichromosome loss protein, Mcl1, middle region Ku_PK_bind PF08785.11 PFH34214.1 - 2.7e-20 72.7 0.0 6.4e-14 52.1 0.0 2.5 1 1 1 2 2 2 2 Ku C terminal domain like Ku PF02735.16 PFH34214.1 - 5.8e-19 68.6 0.0 1.4e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain VWA_2 PF13519.6 PFH34214.1 - 0.04 14.6 0.0 2.4 8.8 0.0 2.9 3 0 0 3 3 3 0 von Willebrand factor type A domain Ku_C PF03730.14 PFH34214.1 - 0.088 13.5 3.8 0.7 10.6 0.0 3.1 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm CBP4 PF07960.11 PFH34214.1 - 1.2 9.0 7.1 3.7 7.4 7.0 1.8 2 0 0 2 2 2 0 CBP4 IPPT PF01715.17 PFH34215.1 - 4.3e-54 183.7 0.0 5.4e-53 180.1 0.0 2.2 1 1 0 1 1 1 1 IPP transferase AAA_22 PF13401.6 PFH34215.1 - 0.0044 17.3 0.1 0.014 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain IPT PF01745.16 PFH34215.1 - 0.015 14.7 0.1 0.031 13.7 0.0 1.5 2 0 0 2 2 2 0 Isopentenyl transferase PhoH PF02562.16 PFH34215.1 - 0.022 14.2 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 PFH34215.1 - 0.026 14.7 0.5 0.11 12.7 0.0 2.5 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 PFH34215.1 - 0.027 14.9 1.4 0.31 11.4 1.4 2.5 1 1 0 1 1 1 0 AAA ATPase domain RRM_1 PF00076.22 PFH34216.1 - 6e-40 134.9 0.1 8.5e-18 63.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PFH34216.1 - 3.8e-06 26.5 0.0 4.4e-05 23.1 0.0 2.4 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PFH34216.1 - 5.7e-06 26.1 0.0 0.021 14.7 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 PFH34216.1 - 4.7e-05 23.3 0.1 0.074 13.1 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_9 PF18444.1 PFH34216.1 - 0.017 15.0 0.2 6.2 6.8 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif RBM39linker PF15519.6 PFH34216.1 - 0.021 15.9 0.2 0.021 15.9 0.2 3.4 4 0 0 4 4 4 0 linker between RRM2 and RRM3 domains in RBM39 protein PHM7_cyt PF14703.6 PFH34216.1 - 0.048 13.9 5.8 9.9 6.3 4.8 2.5 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter IF4E PF01652.18 PFH34217.1 - 2.4e-13 50.2 0.0 4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.25 PFH34218.1 - 6.3e-55 186.4 0.0 6.1e-32 111.0 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34218.1 - 1.1e-21 77.2 0.0 4.3e-20 72.1 0.0 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PFH34218.1 - 0.027 13.4 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 PFH34218.1 - 0.19 11.0 0.3 0.59 9.5 0.3 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CLASP_N PF12348.8 PFH34221.1 - 4.7e-11 42.7 0.3 6.5e-11 42.2 0.3 1.1 1 0 0 1 1 1 1 CLASP N terminal Adaptin_N PF01602.20 PFH34221.1 - 0.0027 16.4 0.0 0.037 12.6 0.0 2.0 1 1 1 2 2 2 1 Adaptin N terminal region HEAT_EZ PF13513.6 PFH34221.1 - 0.011 16.2 1.5 2.5 8.7 0.1 2.9 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.6 PFH34221.1 - 0.051 14.0 2.8 2.7 8.5 0.3 3.3 3 1 0 3 3 3 0 HEAT repeats HSP20 PF00011.21 PFH34222.1 - 7e-21 74.3 0.0 9.5e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PFH34222.1 - 1.7e-06 27.5 0.0 2.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA TRAUB PF08164.12 PFH34223.1 - 1.8e-16 60.4 2.8 2.2e-16 60.1 0.1 2.5 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 PFH34223.1 - 7.5e-12 46.1 1.8 4.6e-11 43.6 0.2 2.7 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor ATP-synt_Eps PF04627.13 PFH34223.1 - 2.1 8.4 4.5 1.5 8.9 0.5 2.5 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain Pkinase PF00069.25 PFH34224.1 - 1.6e-17 63.7 0.0 3.2e-17 62.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 PFH34224.1 - 2.7e-05 23.6 0.0 4.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH34224.1 - 0.0017 17.7 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH34224.1 - 0.0043 17.0 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PFH34224.1 - 0.15 11.0 0.1 0.27 10.3 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Mg_trans_NIPA PF05653.14 PFH34225.1 - 9.2e-20 70.9 7.1 5.9e-10 38.7 0.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Pkinase PF00069.25 PFH34226.1 - 2e-16 60.1 0.0 3.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PFH34226.1 - 2.6e-08 33.5 0.0 4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH34226.1 - 0.00069 19.0 0.0 0.00094 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PFH34226.1 - 0.0039 16.6 0.0 0.0088 15.4 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 PFH34227.1 - 1.1e-12 47.9 0.0 2.1e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PFH34227.1 - 5.6e-05 22.6 0.0 8.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH34227.1 - 0.0029 16.9 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH34227.1 - 0.018 15.0 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 PFH34227.1 - 0.037 13.4 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PFH34227.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Arm PF00514.23 PFH34228.1 - 7.9e-09 35.3 2.7 0.11 12.5 0.0 8.2 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat BAF250_C PF12031.8 PFH34228.1 - 0.78 9.0 7.3 2.5 7.3 0.0 3.9 4 0 0 4 4 4 0 SWI/SNF-like complex subunit BAF250/Osa Peptidase_S64 PF08192.11 PFH34229.1 - 7.9 4.8 9.3 15 3.9 9.3 1.4 1 0 0 1 1 1 0 Peptidase family S64 PUB PF09409.10 PFH34230.1 - 8e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 PUB domain TH1 PF04858.13 PFH34231.1 - 3.9e-06 25.8 1.2 0.0047 15.6 0.0 3.2 4 0 0 4 4 4 2 TH1 protein Abhydrolase_6 PF12697.7 PFH34232.1 - 5e-13 50.2 2.6 5e-13 50.2 2.6 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PFH34232.1 - 3.2e-08 33.5 0.0 0.0074 16.0 0.0 3.1 3 0 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PFH34232.1 - 4.5e-05 22.8 0.3 0.21 10.8 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Palm_thioest PF02089.15 PFH34232.1 - 0.003 17.4 0.0 0.022 14.6 0.0 2.0 1 1 0 1 1 1 1 Palmitoyl protein thioesterase MRP-L27 PF09809.9 PFH34234.1 - 6.2e-13 48.6 0.0 8.8e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 MSP1_C PF07462.11 PFH34235.1 - 0.0043 15.8 0.3 0.026 13.2 0.0 2.2 2 0 0 2 2 2 1 Merozoite surface protein 1 (MSP1) C-terminus Hydrolase_4 PF12146.8 PFH34235.1 - 0.0068 15.7 0.1 0.015 14.5 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SF-assemblin PF06705.11 PFH34235.1 - 0.019 14.3 0.2 0.034 13.5 0.2 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin XRCC4 PF06632.12 PFH34237.1 - 0.0019 17.1 1.9 0.0019 17.1 1.9 3.1 4 0 0 4 4 4 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 PA PF02225.22 PFH34239.1 - 6.8e-06 26.0 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 PA domain DUF2681 PF10883.8 PFH34239.1 - 0.5 10.8 3.2 0.71 10.3 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) CLP1_P PF16575.5 PFH34241.1 - 3e-21 76.1 0.0 5.3e-16 59.0 0.0 3.3 2 1 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop Cys_Met_Meta_PP PF01053.20 PFH34243.1 - 1.5e-123 412.1 0.0 1.8e-123 411.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 PFH34243.1 - 5.7e-08 32.3 0.1 7.8e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 PFH34243.1 - 1.5e-06 27.8 0.0 3.6e-06 26.5 0.0 1.5 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 PFH34243.1 - 1.8e-06 27.2 0.0 6.6e-06 25.3 0.0 2.0 2 1 0 2 2 2 1 Aminotransferase class-V SepSecS PF05889.13 PFH34243.1 - 0.02 13.6 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Nop16 PF09420.10 PFH34245.1 - 7.6e-09 35.9 0.1 7.6e-09 35.9 0.1 3.1 2 1 1 3 3 3 2 Ribosome biogenesis protein Nop16 Ubiq_cyt_C_chap PF03981.12 PFH34245.1 - 0.44 10.6 5.6 0.1 12.7 1.2 1.9 1 1 0 2 2 2 0 Ubiquinol-cytochrome C chaperone RNase_J_C PF17770.1 PFH34245.1 - 0.59 11.2 7.3 7.7 7.6 0.3 3.4 3 1 0 3 3 3 0 Ribonuclease J C-terminal domain TPH PF13868.6 PFH34247.1 - 1.2e-54 185.1 151.0 1.2e-54 185.1 151.0 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain DEAD PF00270.29 PFH34248.1 - 9.4e-47 159.0 0.1 2.3e-46 157.8 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH34248.1 - 1.1e-23 83.6 0.0 1.4e-22 80.1 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PFH34248.1 - 5.4e-20 71.4 0.6 1e-19 70.5 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PFH34248.1 - 5.6e-05 23.2 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PFH34250.1 - 1.9e-43 148.3 0.0 2.6e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH34250.1 - 1.5e-29 102.6 0.9 9.1e-29 100.1 0.4 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH34250.1 - 0.0019 18.2 0.0 0.0046 17.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PFH34250.1 - 0.042 13.2 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 PFH34250.1 - 0.21 11.6 0.3 0.58 10.1 0.3 1.8 1 1 0 1 1 1 0 Flavivirus DEAD domain Sulfate_transp PF00916.20 PFH34251.1 - 2e-80 270.4 10.5 2.9e-80 269.9 10.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PFH34251.1 - 1.6e-19 69.6 0.0 2.7e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain Scs3p PF10261.9 PFH34252.1 - 4.9e-05 23.0 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF898 PF05987.13 PFH34252.1 - 0.27 10.2 2.9 6.6 5.7 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) CNDH2_C PF16858.5 PFH34253.1 - 0.55 10.1 3.1 0.21 11.4 0.2 1.7 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SpoIIIAH PF12685.7 PFH34253.1 - 2.7 7.8 6.8 1.8 8.4 2.5 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein adh_short PF00106.25 PFH34254.1 - 7.7e-30 103.8 0.0 1.6e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PFH34254.1 - 8.9e-20 71.2 0.0 1.5e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PFH34254.1 - 0.00028 20.8 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PFH34254.1 - 0.077 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) IF-2B PF01008.17 PFH34255.1 - 3.4e-47 161.0 0.1 4.7e-37 127.7 0.0 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family Sugarporin_N PF11471.8 PFH34256.1 - 0.045 13.7 0.4 0.12 12.3 0.4 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF3584 PF12128.8 PFH34257.1 - 0.18 9.3 33.9 0.24 8.9 33.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_23 PF13476.6 PFH34257.1 - 0.77 10.2 10.7 1.3 9.4 10.7 1.4 1 0 0 1 1 1 0 AAA domain TMEM52 PF14979.6 PFH34257.1 - 2.4 8.1 7.0 0.16 11.9 0.9 2.1 2 0 0 2 2 2 0 Transmembrane 52 LMBR1 PF04791.16 PFH34257.1 - 2.6 6.8 6.2 3.9 6.3 6.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein HIP1_clath_bdg PF16515.5 PFH34257.1 - 4.6 7.9 29.4 0.77 10.4 14.4 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_13 PF13166.6 PFH34257.1 - 9.8 4.7 24.3 13 4.3 24.3 1.1 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 PFH34258.1 - 3e-78 261.9 0.1 5.6e-78 261.1 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 PFH34258.1 - 2.4e-30 105.1 0.8 2.4e-30 105.1 0.8 2.8 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.19 PFH34258.1 - 2.8e-13 49.9 0.1 3.9e-12 46.2 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 PFH34258.1 - 1.9e-06 28.1 0.2 6.6e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 PFH34258.1 - 9e-06 25.4 0.1 5.5e-05 22.8 0.1 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 PFH34258.1 - 2.6e-05 24.7 2.3 0.00032 21.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 PFH34258.1 - 9.4e-05 21.5 0.2 0.0029 16.6 0.0 2.8 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 PFH34258.1 - 9.5e-05 22.8 0.0 0.00044 20.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 PFH34258.1 - 0.00011 22.0 0.0 0.00036 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PFH34258.1 - 0.00087 18.6 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 PFH34258.1 - 0.0013 19.0 0.2 0.031 14.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain CbiA PF01656.23 PFH34258.1 - 0.0021 18.1 0.0 0.004 17.2 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 PFH34258.1 - 0.0069 16.3 0.7 0.029 14.3 0.0 2.5 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Fe-ADH PF00465.19 PFH34258.1 - 0.0076 15.1 0.2 0.041 12.7 0.0 2.2 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase SRPRB PF09439.10 PFH34258.1 - 0.011 15.1 0.3 5.8 6.3 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit CLP1_P PF16575.5 PFH34258.1 - 0.025 14.4 0.0 0.46 10.3 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_31 PF13614.6 PFH34258.1 - 0.027 14.4 0.1 0.91 9.4 0.0 2.4 1 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 PFH34258.1 - 0.029 14.2 0.1 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.20 PFH34258.1 - 0.032 14.1 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 PFH34258.1 - 0.055 13.4 0.7 1.4 8.8 0.7 2.5 1 1 0 1 1 1 0 NTPase MipZ PF09140.11 PFH34258.1 - 0.063 12.6 0.1 1.1 8.4 0.0 2.3 1 1 0 1 1 1 0 ATPase MipZ DNA_pol3_chi PF04364.13 PFH34258.1 - 0.073 13.2 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC DUF2209 PF09974.9 PFH34258.1 - 0.079 13.3 0.2 0.24 11.8 0.2 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) ResIII PF04851.15 PFH34258.1 - 0.083 12.9 0.6 1.7 8.6 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.23 PFH34258.1 - 0.11 12.6 0.4 0.9 9.6 0.4 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 PFH34258.1 - 0.11 12.0 0.1 0.38 10.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.11 PFH34258.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein RNA_pol_A_bac PF01000.26 PFH34260.1 - 6.5e-07 29.7 0.0 1.2e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain HHH_5 PF14520.6 PFH34260.1 - 7.4e-07 29.7 0.0 1.5e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.15 PFH34260.1 - 0.00028 20.6 0.0 0.00047 19.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_L PF01193.24 PFH34260.1 - 0.0011 18.3 0.0 0.0029 17.0 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DNA_pol_lambd_f PF10391.9 PFH34260.1 - 0.093 12.6 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Nop14 PF04147.12 PFH34261.1 - 4.4e-40 137.7 103.1 1.8e-28 99.3 81.5 5.3 2 1 2 4 4 4 3 Nop14-like family Iso_dh PF00180.20 PFH34262.1 - 2.4e-73 247.3 0.0 2.9e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IDH PF03971.14 PFH34262.1 - 0.002 16.7 0.0 0.25 9.8 0.0 2.0 2 0 0 2 2 2 2 Monomeric isocitrate dehydrogenase Rbx_binding PF18113.1 PFH34262.1 - 0.079 12.8 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Rubredoxin binding C-terminal domain DUF89 PF01937.19 PFH34263.1 - 3.3e-69 233.5 0.0 4.1e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Peptidase_M48 PF01435.18 PFH34263.1 - 0.013 15.2 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M48 Cmc1 PF08583.10 PFH34264.1 - 0.068 13.2 1.0 0.49 10.4 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pkinase PF00069.25 PFH34265.1 - 2.4e-51 174.7 0.0 3.9e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34265.1 - 9.4e-25 87.4 0.1 3.3e-24 85.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 PFH34265.1 - 0.0019 17.8 0.0 0.0019 17.8 0.0 2.5 2 1 0 2 2 2 1 RIO1 family Pox_ser-thr_kin PF05445.11 PFH34265.1 - 0.16 10.9 0.4 0.27 10.1 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Ras PF00071.22 PFH34266.1 - 1.1e-56 190.9 0.4 1.3e-56 190.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH34266.1 - 2.7e-35 121.2 0.1 4.3e-35 120.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH34266.1 - 1.4e-19 70.3 0.1 1.8e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PFH34266.1 - 3.8e-08 33.0 0.1 4.7e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PFH34266.1 - 1.3e-06 28.4 0.0 8e-06 25.9 0.0 1.9 1 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PFH34266.1 - 6.3e-05 22.9 0.9 0.02 14.8 0.1 2.3 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 PFH34266.1 - 8.9e-05 22.1 0.1 0.00033 20.3 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PFH34266.1 - 0.00012 21.6 0.1 0.00037 20.0 0.0 1.7 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 PFH34266.1 - 0.003 18.0 0.1 0.0057 17.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 PFH34266.1 - 0.0068 16.2 0.1 0.034 13.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 PFH34266.1 - 0.019 14.7 0.1 0.059 13.1 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 PFH34266.1 - 0.033 14.5 0.0 0.053 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PFH34266.1 - 0.035 14.1 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 PFH34266.1 - 0.054 13.4 0.0 0.71 9.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 PFH34266.1 - 0.06 13.9 0.2 0.22 12.0 0.2 2.0 1 1 0 1 1 1 0 ABC transporter MCM PF00493.23 PFH34266.1 - 0.066 12.3 0.1 0.34 10.0 0.0 1.8 1 1 1 2 2 2 0 MCM P-loop domain TniB PF05621.11 PFH34266.1 - 0.068 12.6 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DUF815 PF05673.13 PFH34266.1 - 0.068 12.3 0.0 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FeoB_N PF02421.18 PFH34266.1 - 0.074 12.6 0.0 0.69 9.4 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 PFH34266.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region LRR_4 PF12799.7 PFH34267.1 - 1.4e-05 25.3 12.0 0.064 13.7 0.1 5.1 2 2 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH34267.1 - 0.00048 19.8 11.4 0.17 11.7 0.2 4.1 3 1 0 3 3 3 2 Leucine rich repeat F-box-like_2 PF13013.6 PFH34267.1 - 0.12 12.4 0.0 0.41 10.6 0.0 1.9 1 0 0 1 1 1 0 F-box-like domain Mob1_phocein PF03637.17 PFH34269.1 - 3.6e-24 85.7 3.3 8.2e-15 55.2 1.9 3.2 3 0 0 3 3 3 3 Mob1/phocein family EIF_2_alpha PF07541.12 PFH34270.1 - 9.3e-33 112.8 0.1 2.3e-32 111.5 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 PFH34270.1 - 4e-11 43.1 0.8 1.3e-10 41.4 0.2 2.2 2 0 0 2 2 2 1 S1 RNA binding domain FSIP1 PF15554.6 PFH34270.1 - 0.0047 16.1 3.0 0.008 15.3 3.0 1.3 1 0 0 1 1 1 1 FSIP1 family Cwf_Cwc_15 PF04889.12 PFH34270.1 - 0.027 14.2 5.2 0.036 13.8 5.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBECR2 PF18810.1 PFH34270.1 - 0.088 13.1 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 EcKinase PF02958.20 PFH34270.1 - 0.15 11.3 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase TFIIA PF03153.13 PFH34270.1 - 0.28 11.1 5.9 0.28 11.1 5.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 PFH34270.1 - 9.8 6.4 16.8 17 5.6 16.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DEAD PF00270.29 PFH34272.1 - 2.3e-41 141.5 0.0 7.3e-40 136.6 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH34272.1 - 2.9e-34 117.7 0.5 5.4e-34 116.9 0.5 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PFH34272.1 - 0.005 16.1 0.2 0.008 15.4 0.2 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 PFH34272.1 - 0.017 13.9 0.0 0.078 11.7 0.0 1.9 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.15 PFH34272.1 - 0.067 13.2 0.0 0.16 11.9 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit WD40 PF00400.32 PFH34274.1 - 3.7e-31 106.7 23.5 2.1e-05 25.1 0.7 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH34274.1 - 5.1e-08 33.1 2.5 0.33 11.3 0.0 5.9 5 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PFH34274.1 - 0.0027 16.7 0.0 0.2 10.6 0.0 3.1 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein MORN PF02493.20 PFH34275.1 - 4.4e-41 136.4 58.7 1.3e-07 31.1 5.8 9.9 10 0 0 10 10 10 8 MORN repeat BsuPI PF12690.7 PFH34275.1 - 0.013 15.6 2.9 0.42 10.7 0.1 3.1 2 1 1 3 3 3 0 Intracellular proteinase inhibitor Tudor_2 PF18104.1 PFH34275.1 - 0.73 9.6 2.9 67 3.3 0.2 4.2 4 0 0 4 4 4 0 Jumonji domain-containing protein 2A Tudor domain YL1 PF05764.13 PFH34276.1 - 5.8e-21 75.7 52.6 5.8e-21 75.7 52.6 3.9 3 1 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 PFH34276.1 - 2.7e-11 43.0 0.1 5.1e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DnaJ-X PF14308.6 PFH34277.1 - 1.3e-54 184.8 1.6 1.3e-54 184.8 1.6 2.4 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 PFH34277.1 - 1.9e-27 95.1 2.7 4.6e-27 93.9 2.7 1.7 1 0 0 1 1 1 1 DnaJ domain ORC6 PF05460.13 PFH34277.1 - 0.0016 17.8 0.5 0.0016 17.8 0.5 1.9 3 1 0 3 3 3 1 Origin recognition complex subunit 6 (ORC6) Pkinase PF00069.25 PFH34279.1 - 1.2e-20 74.0 0.0 6.2e-20 71.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PFH34279.1 - 2.4e-17 63.2 0.0 2.8e-16 59.7 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH34279.1 - 1.8e-11 43.9 0.0 2e-10 40.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Fungal_TACC PF12709.7 PFH34280.1 - 0.032 14.7 0.7 0.032 14.7 0.7 10.0 8 4 4 12 12 12 0 Fungal Transforming acidic coiled-coil (TACC) proteins ANAPC4_WD40 PF12894.7 PFH34281.1 - 2.3e-07 31.0 0.0 0.00063 20.0 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PFH34281.1 - 3.2e-05 24.6 1.4 5.3 8.1 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat PD40 PF07676.12 PFH34281.1 - 0.053 13.5 1.5 14 5.8 0.1 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat SGL PF08450.12 PFH34281.1 - 0.16 11.5 0.0 16 5.0 0.0 3.3 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Fur_reg_FbpA PF13076.6 PFH34282.1 - 0.2 11.4 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Fur-regulated basic protein A LRR_6 PF13516.6 PFH34283.1 - 4.4e-06 26.3 0.5 0.07 13.2 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich repeat DUF740 PF05340.12 PFH34284.1 - 0.017 13.9 6.9 0.022 13.5 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF883 PF05957.13 PFH34284.1 - 0.11 13.1 6.6 0.2 12.3 1.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Cauli_AT PF03233.13 PFH34284.1 - 0.19 11.7 4.3 0.26 11.2 4.3 1.2 1 0 0 1 1 1 0 Aphid transmission protein Exonuc_VII_L PF02601.15 PFH34284.1 - 2.7 7.5 9.7 3.6 7.1 9.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ribosomal_L6e PF01159.19 PFH34286.1 - 1.3e-35 122.3 1.3 1.8e-35 121.8 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e DUF5619 PF18505.1 PFH34286.1 - 0.15 12.1 0.2 0.29 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5619) DnaJ PF00226.31 PFH34287.1 - 1e-28 99.2 1.4 1.5e-28 98.7 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain Transcrip_act PF04949.13 PFH34287.1 - 0.04 13.8 0.3 0.065 13.1 0.3 1.2 1 0 0 1 1 1 0 Transcriptional activator RPN1_RPN2_N PF17781.1 PFH34288.1 - 1.1e-94 317.3 0.0 1.7e-94 316.7 0.0 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 PFH34288.1 - 4.6e-27 93.8 0.0 8.7e-27 92.9 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 PFH34288.1 - 1.9e-16 59.5 22.2 0.00069 19.9 0.3 8.9 8 0 0 8 8 8 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 PFH34288.1 - 0.14 12.6 5.6 2.1 8.8 0.2 4.2 3 2 2 5 5 5 0 HEAT repeats AAA_33 PF13671.6 PFH34289.1 - 3.9e-07 30.3 0.0 0.055 13.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 PFH34289.1 - 0.0001 22.8 0.1 0.0031 18.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 PFH34289.1 - 0.0013 18.2 0.0 0.03 13.8 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 PFH34289.1 - 0.0017 18.8 0.0 0.0017 18.8 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 PFH34289.1 - 0.0027 18.1 0.0 0.0056 17.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PFH34289.1 - 0.0099 16.2 0.0 0.035 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain MTA_R1 PF17226.2 PFH34289.1 - 0.02 15.0 0.5 0.048 13.8 0.5 1.6 1 0 0 1 1 1 0 MTA R1 domain AAA_28 PF13521.6 PFH34289.1 - 0.049 13.9 0.0 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 PFH34289.1 - 0.076 12.9 0.1 7.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 PFH34289.1 - 0.093 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 PFH34289.1 - 0.24 11.3 0.0 0.86 9.5 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Nucleoporin_FG PF13634.6 PFH34290.1 - 7.1e-32 110.1 208.8 8.7e-09 36.1 22.8 10.0 3 1 10 13 13 13 10 Nucleoporin FG repeat region Clat_adaptor_s PF01217.20 PFH34293.1 - 1.2e-42 145.2 0.1 1.3e-42 145.1 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HhH-GPD PF00730.25 PFH34294.1 - 1.2e-17 64.3 0.0 2.3e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 PFH34294.1 - 6.7e-05 22.6 0.0 0.00022 20.9 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif NUDIX_4 PF14815.6 PFH34294.1 - 0.0011 18.9 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 2 NUDIX domain HHH_5 PF14520.6 PFH34294.1 - 0.0042 17.7 0.0 0.068 13.8 0.0 2.4 1 1 1 2 2 2 1 Helix-hairpin-helix domain Fez1 PF06818.15 PFH34295.1 - 0.00054 20.5 19.2 0.00054 20.5 19.2 5.0 2 1 3 6 6 6 1 Fez1 CENP-F_leu_zip PF10473.9 PFH34295.1 - 0.01 15.8 96.7 0.032 14.3 21.4 7.5 3 2 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LMSTEN PF07988.12 PFH34295.1 - 0.58 9.7 6.6 1.8 8.1 5.9 2.3 1 1 0 1 1 1 0 LMSTEN motif UPF0242 PF06785.11 PFH34295.1 - 2.3 8.3 100.3 0.3 11.2 16.6 5.2 3 2 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DUF1242 PF06842.12 PFH34298.1 - 4.7e-15 55.1 0.4 7.4e-15 54.5 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Ribosomal_L22 PF00237.19 PFH34300.1 - 1.6e-20 73.2 0.0 2.5e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L7Ae PF01248.26 PFH34301.1 - 1.5e-17 63.1 0.1 3.9e-17 61.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RCC1 PF00415.18 PFH34302.1 - 1.5e-35 121.6 12.0 5e-14 52.6 0.1 7.2 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH34302.1 - 4e-32 109.3 21.1 8.2e-08 31.9 0.9 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Cyt-b5 PF00173.28 PFH34303.1 - 1.4e-18 66.8 0.0 2.2e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FPL PF09758.9 PFH34304.1 - 1.7e-56 190.3 5.1 2.6e-56 189.8 5.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein DDHD PF02862.17 PFH34305.1 - 4e-30 105.6 5.4 4e-30 105.6 5.4 3.9 2 2 0 2 2 2 1 DDHD domain DUF676 PF05057.14 PFH34305.1 - 0.12 11.9 0.1 0.27 10.7 0.0 1.5 2 0 0 2 2 2 0 Putative serine esterase (DUF676) VPS13_C PF16909.5 PFH34306.1 - 3.8e-24 85.4 0.0 6.2e-21 75.0 0.0 2.2 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 PFH34306.1 - 4.2e-10 39.5 0.0 4.1e-05 23.1 0.0 3.2 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 PFH34309.1 - 1.3e-18 67.2 0.1 2.3e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ETF_alpha PF00766.19 PFH34311.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain zf-C2HC_2 PF13913.6 PFH34312.1 - 9.1e-07 28.6 11.4 0.0005 19.9 0.6 3.6 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zf-TRAF PF02176.18 PFH34312.1 - 0.0031 18.2 3.3 0.0085 16.8 3.3 1.7 1 0 0 1 1 1 1 TRAF-type zinc finger zf-C2H2_4 PF13894.6 PFH34312.1 - 0.014 16.1 5.7 19 6.5 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger PRP21_like_P PF12230.8 PFH34312.1 - 0.014 15.2 0.2 0.014 15.2 0.2 1.6 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf_UBZ PF18439.1 PFH34312.1 - 0.091 12.4 0.4 0.091 12.4 0.4 2.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Trm112p PF03966.16 PFH34312.1 - 0.17 12.5 0.2 0.52 10.9 0.2 1.8 1 0 0 1 1 1 0 Trm112p-like protein DUF2318 PF10080.9 PFH34312.1 - 0.22 11.7 8.6 3.3 7.9 0.1 3.5 3 1 1 4 4 4 0 Predicted membrane protein (DUF2318) zf-Di19 PF05605.12 PFH34312.1 - 0.6 10.4 10.2 0.14 12.5 1.1 3.3 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding FAM76 PF16046.5 PFH34312.1 - 9.1 5.5 15.5 1 8.7 3.2 2.6 3 0 0 3 3 3 0 FAM76 protein Adaptin_N PF01602.20 PFH34313.1 - 4.4e-125 418.2 0.2 5.3e-125 417.9 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 PFH34313.1 - 1.5e-18 67.1 0.0 4.3e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 PFH34313.1 - 4.8e-09 36.5 4.5 3.1e-06 27.3 0.0 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PFH34313.1 - 0.00029 21.2 6.6 0.07 13.5 0.0 4.3 4 1 1 5 5 5 2 HEAT repeats DUF5578 PF17741.1 PFH34313.1 - 0.3 10.5 2.3 14 5.0 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5578) Arm PF00514.23 PFH34313.1 - 3.4 7.9 8.3 23 5.2 0.0 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cation_efflux PF01545.21 PFH34314.1 - 2.7 7.7 12.5 0.098 12.4 0.9 2.4 2 0 0 2 2 2 0 Cation efflux family Sel1 PF08238.12 PFH34315.1 - 1e-18 67.3 27.2 5.6e-06 26.8 0.0 10.1 13 0 0 13 13 13 7 Sel1 repeat EF-hand_like PF09279.11 PFH34315.1 - 2.1 8.9 3.8 0.93 10.0 0.4 2.2 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like RecA PF00154.21 PFH34317.1 - 0.066 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Suf PF05843.14 PFH34317.1 - 0.09 12.7 4.8 1.8 8.5 0.1 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 PFH34317.1 - 0.17 11.9 1.1 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3c_N PF05470.12 PFH34317.1 - 9.7 4.4 5.6 15 3.8 5.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RRM_1 PF00076.22 PFH34318.1 - 0.039 13.8 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArfGap PF01412.18 PFH34318.1 - 3.1 7.9 5.1 8.1 6.6 5.1 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf zf-CCCH PF00642.24 PFH34319.1 - 6.1e-07 29.2 21.1 0.00057 19.7 7.4 3.4 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PFH34319.1 - 1.3e-06 28.1 17.6 3.4e-05 23.5 8.1 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 PFH34319.1 - 4.8e-06 27.2 8.2 1.2e-05 26.0 1.6 2.1 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 PFH34319.1 - 6.5e-06 26.0 19.7 0.00093 19.2 9.0 3.4 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH_3 PF15663.5 PFH34319.1 - 1.3e-05 25.4 8.5 2.2e-05 24.6 6.5 1.9 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 PFH34319.1 - 0.011 16.2 9.6 0.57 10.7 6.2 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-C3HC4_3 PF13920.6 PFH34322.1 - 3.3e-06 26.8 4.4 3.3e-06 26.8 4.4 3.4 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PFH34322.1 - 0.0016 18.2 3.7 0.0016 18.2 3.7 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PFH34322.1 - 0.081 13.1 2.5 0.33 11.1 2.5 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PFH34322.1 - 2.1 8.3 15.5 3.2 7.7 6.3 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 CEP44 PF15007.6 PFH34325.1 - 3.3e-41 140.4 0.0 6.3e-41 139.5 0.0 1.5 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 CCDC53 PF10152.9 PFH34325.1 - 0.092 13.2 0.2 0.28 11.6 0.2 1.9 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex FlxA PF14282.6 PFH34325.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 FlxA-like protein NPV_P10 PF05531.12 PFH34325.1 - 0.17 12.4 1.5 0.97 9.9 0.3 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Bromo_TP PF07524.13 PFH34326.1 - 4.9e-05 23.3 0.0 8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 PFH34326.1 - 0.005 17.4 4.5 0.015 15.8 4.5 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Hexapep PF00132.24 PFH34327.1 - 2.5e-07 30.1 4.4 2.1e-05 24.1 0.8 3.2 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PFH34327.1 - 0.026 14.3 3.3 2 8.2 4.0 2.6 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase RIBIOP_C PF04950.12 PFH34328.1 - 2.6e-72 243.7 0.0 2.6e-72 243.7 0.0 2.4 3 0 0 3 3 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 PFH34328.1 - 1.6e-24 85.8 0.0 8.1e-24 83.5 0.0 2.3 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_33 PF13671.6 PFH34328.1 - 5e-06 26.7 0.1 0.00015 22.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 PFH34328.1 - 2.8e-05 23.8 1.9 0.00035 20.2 0.0 2.9 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 PFH34328.1 - 0.0001 22.7 0.0 0.00027 21.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PFH34328.1 - 0.00013 22.4 0.0 0.00013 22.4 0.0 2.7 3 1 0 3 3 1 1 AAA ATPase domain AAA_30 PF13604.6 PFH34328.1 - 0.00024 20.9 0.0 0.00056 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PFH34328.1 - 0.00025 21.3 0.0 0.00084 19.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 PFH34328.1 - 0.0013 18.8 0.0 0.0033 17.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 PFH34328.1 - 0.0017 18.6 0.1 0.0099 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 PFH34328.1 - 0.0017 17.9 0.0 0.0038 16.8 0.0 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 PFH34328.1 - 0.0019 18.1 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 PFH34328.1 - 0.0024 18.4 2.3 0.0094 16.5 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PFH34328.1 - 0.0045 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PFH34328.1 - 0.0053 16.8 0.1 0.015 15.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 PFH34328.1 - 0.0081 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 PFH34328.1 - 0.0093 16.5 0.7 0.15 12.6 0.0 2.8 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 PFH34328.1 - 0.029 14.8 0.0 0.063 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 PFH34328.1 - 0.031 13.8 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 PFH34328.1 - 0.035 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 PFH34328.1 - 0.037 13.3 0.0 0.094 11.9 0.0 1.6 1 0 0 1 1 1 0 KAP family P-loop domain NTPase_1 PF03266.15 PFH34328.1 - 0.039 13.9 0.1 0.039 13.9 0.1 1.8 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 PFH34328.1 - 0.04 13.7 0.2 0.04 13.7 0.2 4.9 4 1 1 5 5 5 0 AAA domain Rad17 PF03215.15 PFH34328.1 - 0.063 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 PFH34328.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RuvB_N PF05496.12 PFH34328.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 PFH34328.1 - 0.099 12.5 0.3 0.25 11.3 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase SRP54 PF00448.22 PFH34328.1 - 0.099 12.3 1.9 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 PFH34328.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 PFH34328.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea Nup88 PF10168.9 PFH34329.1 - 0.17 9.6 7.4 0.26 9.1 7.4 1.1 1 0 0 1 1 1 0 Nuclear pore component Borrelia_P83 PF05262.11 PFH34329.1 - 0.61 8.5 18.3 1.7 7.1 18.3 1.6 1 0 0 1 1 1 0 Borrelia P83/100 protein 5_nucleotid PF05761.14 PFH34329.1 - 1.7 7.5 7.4 2.9 6.7 7.4 1.3 1 0 0 1 1 1 0 5' nucleotidase family Fmp27_WPPW PF10359.9 PFH34329.1 - 7.3 5.3 10.1 14 4.4 10.1 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain RCC1 PF00415.18 PFH34330.1 - 2e-42 143.6 25.3 2.8e-08 34.2 0.1 9.5 8 1 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH34330.1 - 1.3e-19 69.4 23.7 1.8e-05 24.4 0.0 8.4 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat zf-C3HC4 PF00097.25 PFH34331.1 - 1e-05 25.3 8.7 2.4e-05 24.1 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PFH34331.1 - 3.3e-05 24.1 10.7 3.3e-05 24.1 10.7 2.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 PFH34331.1 - 3.6e-05 23.5 9.6 3.6e-05 23.5 9.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH34331.1 - 0.00015 21.7 7.3 0.00015 21.7 7.3 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PFH34331.1 - 0.0011 19.1 10.7 0.0027 17.8 10.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 PFH34331.1 - 0.0047 16.8 12.0 0.01 15.7 12.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 PFH34331.1 - 0.59 10.0 6.9 2 8.4 6.9 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF572 PF04502.13 PFH34332.1 - 4.8e-53 180.9 0.2 5.4e-53 180.7 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.13 PFH34332.1 - 6.2e-05 23.0 0.9 0.00011 22.2 0.9 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) TF_Zn_Ribbon PF08271.12 PFH34332.1 - 0.0072 15.8 1.1 0.0072 15.8 1.1 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding Zn_ribbon_SprT PF17283.2 PFH34332.1 - 0.29 11.1 0.1 0.29 11.1 0.1 1.7 2 0 0 2 2 2 0 SprT-like zinc ribbon domain HypA PF01155.19 PFH34332.1 - 1.2 9.1 4.4 2 8.5 1.1 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 PFH34332.1 - 1.5 8.8 4.4 8.2 6.4 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Sad1_UNC PF07738.13 PFH34333.1 - 0.25 11.4 0.0 2.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal Flu_NS1 PF00600.19 PFH34334.1 - 0.088 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) IQ PF00612.27 PFH34335.1 - 1.3 9.0 20.1 2 8.5 2.0 4.0 3 0 0 3 3 3 0 IQ calmodulin-binding motif RRM_2 PF04059.12 PFH34336.1 - 5.1e-31 106.7 0.5 8.9e-31 106.0 0.5 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 PFH34336.1 - 0.031 14.1 0.7 0.14 12.0 0.3 2.3 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fib_alpha PF08702.10 PFH34336.1 - 1.4 9.1 5.0 2.8 8.1 5.0 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CRT-like PF08627.10 PFH34337.1 - 4.7e-124 413.7 12.9 5.9e-124 413.4 12.9 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 PFH34337.1 - 1.4e-05 25.2 6.9 1.4e-05 25.2 6.9 3.1 3 0 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 PFH34337.1 - 0.16 11.4 10.5 0.012 15.1 4.7 1.9 2 0 0 2 2 2 0 Solute carrier family 35 GMC_oxred_N PF00732.19 PFH34339.1 - 1.1e-63 215.4 0.0 7.9e-63 212.6 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PFH34339.1 - 2.8e-27 96.0 0.0 2.7e-12 47.4 0.0 3.2 2 1 0 2 2 2 2 GMC oxidoreductase Ribosomal_L19 PF01245.20 PFH34340.1 - 3.7e-13 49.4 1.2 5.3e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L19 PhyH PF05721.13 PFH34341.1 - 4.4e-10 40.2 0.0 4.1e-09 37.0 0.0 2.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) EMG1 PF03587.14 PFH34342.1 - 2.1e-56 190.6 0.0 2.5e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase SPOUT_MTase PF02590.17 PFH34342.1 - 0.0059 16.6 0.0 0.0089 16.0 0.0 1.2 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase CBF PF03914.17 PFH34343.1 - 6e-33 114.3 1.0 6e-33 114.3 1.0 2.7 2 1 0 2 2 2 1 CBF/Mak21 family SelR PF01641.18 PFH34344.1 - 3.7e-05 23.8 0.0 5.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 SelR domain Cyto_heme_lyase PF01265.17 PFH34347.1 - 1.2e-41 143.2 0.6 7.2e-41 140.7 0.6 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase RRM_1 PF00076.22 PFH34348.1 - 0.00011 22.0 0.0 0.0024 17.7 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.26 PFH34351.1 - 1.6e-35 122.3 0.0 1.8e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Aha1_N PF09229.11 PFH34352.1 - 1.1e-25 90.4 2.6 1.2e-25 90.4 0.0 2.3 2 0 0 2 2 1 1 Activator of Hsp90 ATPase, N-terminal TPR_2 PF07719.17 PFH34352.1 - 1.8e-08 33.9 5.0 0.0069 16.4 0.1 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 PFH34352.1 - 6.6e-06 25.7 3.2 0.26 11.0 0.1 3.4 3 0 0 3 3 3 3 TPR repeat TPR_9 PF13371.6 PFH34352.1 - 4.6e-05 23.5 0.2 0.00011 22.3 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 PFH34352.1 - 0.00026 21.6 7.3 0.00066 20.3 3.6 3.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 PFH34352.1 - 0.0007 19.3 7.6 0.32 10.9 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 PFH34352.1 - 0.0026 18.2 4.7 0.018 15.6 0.5 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 PFH34352.1 - 0.0078 16.5 0.1 15 6.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 PFH34352.1 - 0.029 14.7 1.9 0.089 13.1 1.8 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PFH34352.1 - 0.089 12.9 0.7 4.7 7.4 0.0 2.6 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 PFH34352.1 - 0.093 13.0 4.1 0.29 11.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH34352.1 - 0.12 13.1 3.2 16 6.4 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 PFH34352.1 - 0.36 11.8 9.0 1.1 10.3 0.7 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 PFH34355.1 - 3.5e-12 45.4 9.3 0.37 10.9 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 PFH34355.1 - 1.1e-09 38.7 15.5 0.29 11.7 0.3 8.1 5 2 2 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH34355.1 - 5e-08 33.0 5.5 0.03 14.5 0.1 6.2 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PFH34355.1 - 7.1e-08 32.6 5.1 3 8.7 0.0 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 PFH34355.1 - 1.5e-07 31.0 13.0 0.076 13.2 0.0 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 PFH34355.1 - 2.3e-07 30.4 1.1 0.48 10.3 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 PFH34355.1 - 3.3e-07 30.0 0.0 0.38 11.1 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 PFH34355.1 - 2.6e-06 27.6 19.7 0.17 12.2 0.0 8.9 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 PFH34355.1 - 8.3e-06 25.9 17.6 0.021 15.0 0.1 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 PFH34355.1 - 0.00036 20.3 8.1 1.2 9.1 0.1 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 PFH34355.1 - 0.00079 20.1 35.4 0.44 11.5 0.0 10.2 7 4 6 13 13 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 PFH34355.1 - 2 9.1 40.2 0.46 11.2 1.2 8.0 8 2 2 10 10 8 0 Tetratricopeptide repeat Exonuc_VII_L PF02601.15 PFH34356.1 - 0.045 13.3 8.8 0.052 13.1 8.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1043 PF06295.12 PFH34356.1 - 0.12 12.4 8.2 3.7 7.6 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1043) O-antigen_lig PF13425.6 PFH34356.1 - 0.14 10.9 0.2 0.16 10.7 0.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein PIEZO PF15917.5 PFH34356.1 - 0.22 11.0 11.6 0.29 10.6 11.6 1.1 1 0 0 1 1 1 0 Piezo STAT_alpha PF01017.20 PFH34356.1 - 0.22 11.4 9.8 0.19 11.6 8.7 1.3 1 1 0 1 1 1 0 STAT protein, all-alpha domain FapA PF03961.13 PFH34356.1 - 0.38 9.3 7.6 0.44 9.1 7.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prominin PF05478.11 PFH34356.1 - 0.47 8.4 4.0 0.61 8.0 4.0 1.2 1 0 0 1 1 1 0 Prominin LMBR1 PF04791.16 PFH34356.1 - 0.61 8.9 2.0 0.7 8.7 2.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 PFH34356.1 - 0.95 8.3 14.9 1.2 7.9 14.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FliJ PF02050.16 PFH34356.1 - 1.1 9.5 18.0 0.089 13.0 4.2 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein HAUS6_N PF14661.6 PFH34356.1 - 1.3 8.5 13.1 1.9 8.0 13.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TMPIT PF07851.13 PFH34356.1 - 1.6 7.9 10.2 2.4 7.3 10.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein Nup88 PF10168.9 PFH34356.1 - 3 5.5 15.3 17 3.0 15.8 1.7 1 1 1 2 2 2 0 Nuclear pore component Jnk-SapK_ap_N PF09744.9 PFH34356.1 - 3.1 8.0 20.0 7.5 6.8 20.0 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 PFH34356.1 - 3.2 8.3 16.7 3.7 8.1 10.5 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF883 PF05957.13 PFH34356.1 - 7.6 7.2 13.9 1 10.0 8.4 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Exonuc_VII_L PF02601.15 PFH34357.1 - 0.0035 17.0 1.3 0.0043 16.7 1.3 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Laminin_II PF06009.12 PFH34357.1 - 0.0036 17.3 3.6 0.044 13.8 0.9 2.1 1 1 0 2 2 2 1 Laminin Domain II Laminin_I PF06008.14 PFH34357.1 - 0.015 15.0 1.8 0.052 13.2 2.0 1.7 1 1 0 1 1 1 0 Laminin Domain I GAS PF13851.6 PFH34357.1 - 0.05 13.0 9.6 0.064 12.6 9.6 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 PFH34357.1 - 0.05 13.8 15.3 0.25 11.5 2.9 2.1 1 1 1 2 2 2 0 Tropomyosin like ERM PF00769.19 PFH34357.1 - 0.062 13.1 13.6 0.082 12.7 13.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TMPIT PF07851.13 PFH34357.1 - 0.19 10.9 5.4 0.29 10.3 5.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.10 PFH34357.1 - 0.24 11.6 4.4 0.21 11.8 1.4 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4363 PF14276.6 PFH34357.1 - 0.33 11.1 4.7 1.8 8.7 0.1 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4363) DUF2333 PF10095.9 PFH34357.1 - 0.36 9.8 3.9 0.47 9.4 3.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) FapA PF03961.13 PFH34357.1 - 0.45 9.1 3.0 0.61 8.6 3.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A 5_nucleotid PF05761.14 PFH34357.1 - 0.51 9.2 5.0 0.098 11.5 0.4 1.8 1 1 1 2 2 2 0 5' nucleotidase family DUF3337 PF11816.8 PFH34357.1 - 0.52 10.2 5.0 0.72 9.7 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) LMBR1 PF04791.16 PFH34357.1 - 0.54 9.1 5.4 0.89 8.4 5.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4200 PF13863.6 PFH34357.1 - 0.6 10.5 20.1 1.4 9.3 20.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) VSG_B PF13206.6 PFH34357.1 - 0.77 8.9 4.9 1 8.5 4.9 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain P4Ha_N PF08336.11 PFH34357.1 - 1.3 9.1 7.5 2.9 7.9 0.2 2.7 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4446 PF14584.6 PFH34357.1 - 1.4 8.9 4.9 2.3 8.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) YgaB PF14182.6 PFH34357.1 - 1.6 9.2 4.4 0.61 10.5 1.1 1.9 2 0 0 2 2 2 0 YgaB-like protein AATF-Che1 PF13339.6 PFH34357.1 - 1.6 9.4 10.2 2.3 8.9 6.8 1.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor V_ATPase_I PF01496.19 PFH34357.1 - 1.7 6.5 3.1 2.1 6.1 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med9 PF07544.13 PFH34357.1 - 1.9 8.6 9.0 1.2 9.3 5.2 2.2 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 rRNA_processing PF08524.11 PFH34357.1 - 2.6 8.1 18.1 3.5 7.6 18.1 1.1 1 0 0 1 1 1 0 rRNA processing HisKA_3 PF07730.13 PFH34357.1 - 2.9 8.5 7.5 3.1 8.4 2.3 2.5 1 1 1 2 2 2 0 Histidine kinase DUF724 PF05266.14 PFH34357.1 - 4.3 7.1 9.6 5.9 6.7 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) APG6_N PF17675.1 PFH34357.1 - 6.9 7.2 14.6 1.2e+02 3.2 14.6 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region U1snRNP70_N PF12220.8 PFH34357.1 - 7.7 7.2 14.3 6.1 7.6 0.9 2.2 1 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RF-1 PF00472.20 PFH34359.1 - 6.7e-32 109.9 0.5 1.9e-31 108.4 0.5 1.8 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.18 PFH34359.1 - 4e-22 79.0 5.1 1.7e-10 41.1 0.1 2.9 1 1 1 2 2 2 2 PCRF domain TT_ORF2 PF02957.15 PFH34359.1 - 0.0061 17.5 1.0 0.019 15.9 0.4 2.2 1 1 0 1 1 1 1 TT viral ORF2 Asp-B-Hydro_N PF05279.11 PFH34359.1 - 2.8 8.0 6.7 4.8 7.2 4.3 2.0 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region AAR2 PF05282.11 PFH34360.1 - 8.3e-53 180.0 0.3 2.4e-52 178.5 0.3 1.8 1 1 0 1 1 1 1 AAR2 protein RPN2_C PF18004.1 PFH34360.1 - 0.11 12.4 6.3 0.96 9.3 0.3 2.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Ribosomal_TL5_C PF14693.6 PFH34361.1 - 0.0018 18.6 0.0 0.0031 17.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 PFH34361.1 - 0.16 12.5 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L25p family S36_mt PF10937.8 PFH34361.1 - 0.3 12.7 0.1 0.3 12.7 0.1 2.4 2 1 0 2 2 2 0 Ribosomal protein S36, mitochondrial MMR_HSR1 PF01926.23 PFH34363.1 - 1.6e-11 44.3 0.0 3.5e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PFH34363.1 - 3.4e-05 23.4 0.0 5.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 PFH34363.1 - 0.021 14.1 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 AIG1 family NIR_SIR PF01077.22 PFH34363.1 - 0.18 11.3 0.0 0.71 9.4 0.0 1.9 3 0 0 3 3 3 0 Nitrite and sulphite reductase 4Fe-4S domain AAA_16 PF13191.6 PFH34363.1 - 0.24 11.8 3.9 0.44 10.9 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain ABC_membrane_2 PF06472.15 PFH34364.1 - 7.6e-63 212.4 1.2 1.3e-62 211.6 1.2 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PFH34364.1 - 1.1e-18 68.1 0.0 2.6e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PFH34364.1 - 0.00044 20.2 0.1 0.002 18.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 PFH34364.1 - 0.22 11.0 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 PFH34364.1 - 0.91 10.0 2.8 0.6 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain SNF PF00209.18 PFH34365.1 - 2e-120 403.0 38.1 4.1e-118 395.4 35.6 2.7 2 1 0 2 2 2 2 Sodium:neurotransmitter symporter family Toxin_38 PF14866.6 PFH34365.1 - 4.4 7.7 4.7 8.5 6.8 4.7 1.4 1 0 0 1 1 1 0 Potassium channel toxin WW PF00397.26 PFH34366.1 - 4.3e-07 29.9 0.0 9e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 WW domain CKS PF01111.19 PFH34367.1 - 0.037 14.3 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase regulatory subunit BSD PF03909.17 PFH34368.1 - 3.5e-08 33.3 0.2 7.9e-08 32.2 0.2 1.5 1 0 0 1 1 1 1 BSD domain Transket_pyr PF02779.24 PFH34369.1 - 3.6e-41 140.8 0.0 5.9e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PFH34369.1 - 1.2e-36 125.3 0.0 1.9e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Thiamine_BP PF01910.17 PFH34369.1 - 0.042 13.8 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 Thiamine-binding protein Aquarius_N PF16399.5 PFH34370.1 - 7e-206 685.9 0.4 1.1e-181 605.9 0.0 3.6 3 1 0 3 3 3 3 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 PFH34370.1 - 9.2e-23 80.9 0.0 2.6e-22 79.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 PFH34370.1 - 1.2e-22 81.0 0.0 1.2e-22 81.0 0.0 5.1 5 1 0 5 5 3 1 AAA domain AAA_30 PF13604.6 PFH34370.1 - 1.9e-06 27.7 1.2 0.036 13.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.6 PFH34370.1 - 1.6e-05 25.3 0.0 0.00031 21.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PFH34370.1 - 0.0014 18.6 0.0 0.0047 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 PFH34370.1 - 0.0015 18.5 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 PFH34370.1 - 0.0053 16.4 0.0 0.021 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 PFH34370.1 - 0.013 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 PFH34370.1 - 0.071 13.6 0.1 0.071 13.6 0.1 3.3 3 1 0 3 3 2 0 AAA domain UvrD_C_2 PF13538.6 PFH34370.1 - 0.077 12.8 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 PFH34370.1 - 0.092 13.0 0.0 0.69 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PFH34370.1 - 0.11 13.0 0.0 0.39 11.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 PFH34370.1 - 0.17 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 PFH34370.1 - 0.71 10.2 12.4 0.29 11.5 0.0 4.8 4 0 0 4 4 4 0 AAA ATPase domain Clat_adaptor_s PF01217.20 PFH34372.1 - 3.8e-44 150.1 4.2 4.2e-44 149.9 4.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Rhodanese PF00581.20 PFH34373.1 - 1.8e-11 44.5 0.0 2.8e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Ecl1 PF12855.7 PFH34373.1 - 0.012 16.8 1.3 0.018 16.2 1.3 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF2256 PF10013.9 PFH34373.1 - 2.6 8.2 5.8 1.1 9.4 2.7 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DSPn PF14671.6 PFH34374.1 - 6.6e-45 153.0 0.0 1.9e-44 151.5 0.0 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 PFH34374.1 - 2e-11 43.9 0.0 2e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PFH34374.1 - 5.7e-06 26.1 0.0 9.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 PFH34374.1 - 4.7e-05 23.0 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 PFH34374.1 - 0.0013 18.9 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PFH34374.1 - 0.0021 18.1 0.2 0.0095 15.9 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family Methyltransf_14 PF08484.11 PFH34374.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Agouti PF05039.12 PFH34375.1 - 2 9.2 6.7 0.41 11.4 0.2 2.8 2 1 1 3 3 3 0 Agouti protein CPL PF08144.11 PFH34378.1 - 0.00043 20.6 0.5 19 5.6 0.0 4.6 4 1 0 4 4 4 3 CPL (NUC119) domain Phage_Mu_Gam PF07352.12 PFH34378.1 - 0.02 14.8 0.9 0.052 13.5 0.9 1.6 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Vps35 PF03635.17 PFH34378.1 - 0.053 12.0 0.9 0.27 9.7 0.4 1.8 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 35 Peptidase_S8 PF00082.22 PFH34380.1 - 2.6e-45 155.0 5.6 4.3e-45 154.2 5.6 1.3 1 0 0 1 1 1 1 Subtilase family FAM176 PF14851.6 PFH34380.1 - 0.087 12.5 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 FAM176 family CCDC106 PF15794.5 PFH34380.1 - 0.13 12.0 7.5 0.064 13.0 4.7 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Mg_trans_NIPA PF05653.14 PFH34382.1 - 3.1e-11 42.9 7.7 3.9e-07 29.5 3.8 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 PFH34382.1 - 0.013 15.7 4.2 0.013 15.7 4.2 3.0 4 0 0 4 4 4 0 EamA-like transporter family UbiA PF01040.18 PFH34385.1 - 0.036 13.4 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family G6B PF15096.6 PFH34385.1 - 0.31 10.8 3.9 0.22 11.3 0.4 2.2 1 1 2 3 3 3 0 G6B family FAP PF07174.11 PFH34385.1 - 0.47 9.9 9.4 0.73 9.2 9.4 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) SF1-HH PF16275.5 PFH34386.1 - 1.9e-28 99.0 0.1 1.9e-28 99.0 0.1 2.3 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 PFH34386.1 - 1.3e-09 37.7 0.1 2.5e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 PFH34386.1 - 0.24 11.5 1.8 0.51 10.5 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Peptidase_M16_M PF16187.5 PFH34387.1 - 4.2e-14 52.5 0.0 8.2e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 Middle or third domain of peptidase_M16 LEAP-2 PF07359.11 PFH34387.1 - 0.21 11.4 0.6 0.53 10.1 0.1 1.9 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) UCH PF00443.29 PFH34388.1 - 6.8e-23 81.5 0.0 2.6e-17 63.2 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PFH34388.1 - 0.0048 16.5 0.0 0.023 14.3 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SF3b10 PF07189.11 PFH34389.1 - 2e-31 107.9 0.0 2.4e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) ATP-synt_Eps PF04627.13 PFH34390.1 - 5.6e-19 67.9 0.2 7.4e-19 67.5 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ribosomal_L30 PF00327.20 PFH34391.1 - 2.7e-14 52.8 1.5 5.3e-14 51.8 1.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 PFH34391.1 - 2.4e-12 46.9 17.2 3.9e-12 46.2 17.2 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain zf-met2 PF12907.7 PFH34392.1 - 6e-20 71.1 4.8 6e-20 71.1 4.8 1.8 2 0 0 2 2 2 1 Zinc-binding 4F5 PF04419.14 PFH34392.1 - 0.00016 22.5 6.3 0.00032 21.5 6.3 1.5 1 0 0 1 1 1 1 4F5 protein family DUF5407 PF17401.2 PFH34392.1 - 0.0093 16.2 0.2 0.011 16.0 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5407) zf-BED PF02892.15 PFH34392.1 - 0.1 12.7 1.1 0.23 11.5 0.4 1.9 2 0 0 2 2 2 0 BED zinc finger LSM PF01423.22 PFH34393.1 - 4.2e-18 64.8 0.1 5e-18 64.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PFH34393.1 - 0.0029 17.7 0.0 0.0035 17.5 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 PFH34393.1 - 0.038 13.7 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Myosin_head PF00063.21 PFH34394.1 - 4.2e-189 630.1 0.0 5.9e-189 629.6 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 PFH34394.1 - 1.3e-17 64.2 0.1 3.6e-16 59.6 0.0 2.7 2 0 0 2 2 2 1 MyTH4 domain AAA_22 PF13401.6 PFH34394.1 - 0.0037 17.5 2.7 0.08 13.2 0.0 4.1 4 2 1 5 5 5 1 AAA domain PEX11 PF05648.14 PFH34394.1 - 0.026 14.0 0.6 0.12 11.8 0.9 1.8 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) AAA_16 PF13191.6 PFH34394.1 - 0.051 13.9 0.0 0.051 13.9 0.0 3.9 2 1 0 2 2 2 0 AAA ATPase domain IQ PF00612.27 PFH34394.1 - 7.3 6.7 9.4 0.16 11.8 2.3 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif tRNA_m1G_MT PF01746.21 PFH34395.1 - 7.4e-12 45.4 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Ribosomal_L1 PF00687.21 PFH34396.1 - 1.3e-40 139.3 0.0 3.2e-40 138.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF382 PF04037.13 PFH34397.1 - 6.2e-53 178.3 0.2 2e-52 176.7 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 PFH34397.1 - 1.9e-17 62.8 5.2 1.9e-17 62.8 5.2 1.9 2 0 0 2 2 2 1 PSP Nop25 PF09805.9 PFH34397.1 - 0.0035 17.8 5.2 0.0035 17.8 5.2 4.2 5 0 0 5 5 5 1 Nucleolar protein 12 (25kDa) MH1 PF03165.16 PFH34397.1 - 0.11 12.7 0.2 0.23 11.7 0.2 1.4 1 0 0 1 1 1 0 MH1 domain Alg6_Alg8 PF03155.15 PFH34398.1 - 1.1e-121 407.2 7.3 2.9e-120 402.5 2.5 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Sedlin_N PF04628.13 PFH34399.1 - 2.6e-16 60.0 0.0 3.3e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 PFH34399.1 - 0.098 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Sybindin-like family Mito_carr PF00153.27 PFH34400.1 - 8.2e-49 163.5 4.0 4.6e-15 55.3 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Tam41_Mmp37 PF09139.11 PFH34402.1 - 6.8e-54 183.5 0.0 8.8e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial DUF4169 PF13770.6 PFH34405.1 - 6.1 7.2 14.0 0.38 11.0 1.7 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4169) RPAP1_C PF08620.10 PFH34406.1 - 1.3e-25 89.2 0.1 4.5e-25 87.6 0.1 2.0 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 PFH34406.1 - 1.6e-06 27.8 4.9 3.3e-06 26.8 4.9 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal Kinase-like PF14531.6 PFH34407.1 - 2e-38 132.3 0.0 2.9e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH34407.1 - 6e-08 32.4 0.0 0.0004 19.9 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34407.1 - 0.00021 20.7 0.0 0.001 18.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PFH34407.1 - 0.0042 16.7 0.0 0.0068 16.0 0.0 1.4 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 PFH34407.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Nitr_red_bet_C PF14711.6 PFH34408.1 - 0.072 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal RIC1 PF07064.13 PFH34409.1 - 1.6e-14 53.9 0.1 7.8e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 RIC1 UPF0047 PF01894.17 PFH34410.1 - 1.5e-14 54.1 0.0 1.4e-08 34.9 0.0 3.9 3 1 0 3 3 3 3 Uncharacterised protein family UPF0047 DUF1084 PF06454.11 PFH34412.1 - 0.1 12.0 2.6 0.2 11.0 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) Acyl_transf_3 PF01757.22 PFH34412.1 - 8.9 5.3 15.9 0.42 9.6 4.0 2.8 3 0 0 3 3 3 0 Acyltransferase family dCMP_cyt_deam_1 PF00383.23 PFH34413.1 - 1.1e-24 86.2 1.7 1.8e-24 85.5 1.7 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PFH34413.1 - 2.4e-17 63.0 0.1 3.9e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Pep1_7 PF17232.2 PFH34413.1 - 0.023 15.2 1.3 1 9.8 0.1 3.1 2 1 1 3 3 3 0 Elicitor peptide 1-7 SNAD4 PF18750.1 PFH34413.1 - 0.14 12.3 0.1 0.33 11.1 0.1 1.7 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 EF-hand_13 PF17958.1 PFH34415.1 - 3.6e-17 61.9 0.0 1.5e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 PFH34415.1 - 5.2e-09 36.4 1.2 8.1e-07 29.4 1.3 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 PFH34415.1 - 0.025 14.5 6.3 1.2 9.3 0.4 4.4 6 0 0 6 6 6 0 EF-hand domain EF-hand_1 PF00036.32 PFH34415.1 - 0.061 12.9 3.0 0.58 9.8 0.4 3.6 5 0 0 5 5 5 0 EF hand EF-hand_8 PF13833.6 PFH34415.1 - 0.18 11.7 1.0 1.6 8.6 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain pair Myb_DNA-binding PF00249.31 PFH34416.1 - 1.4e-26 92.4 0.9 1.4e-12 47.6 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PFH34416.1 - 7.3e-21 74.2 0.3 6.1e-15 55.2 0.2 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 PFH34416.1 - 0.0055 16.9 0.0 0.81 9.9 0.0 2.3 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Prenyltrans PF00432.21 PFH34417.1 - 5.2e-37 125.3 22.6 1.8e-10 40.3 1.0 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Peptidase_S8 PF00082.22 PFH34419.1 - 2.2e-40 138.8 1.4 3.4e-40 138.2 1.4 1.2 1 0 0 1 1 1 1 Subtilase family Mucin PF01456.17 PFH34419.1 - 0.0041 17.1 1.0 0.013 15.5 1.0 1.8 1 0 0 1 1 1 1 Mucin-like glycoprotein Cu-binding_MopE PF11617.8 PFH34419.1 - 0.11 12.7 4.6 0.37 11.0 4.6 1.9 1 0 0 1 1 1 0 Putative metal-binding motif KIAA1430 PF13879.6 PFH34420.1 - 3.7e-15 56.5 1.1 4.1e-15 56.4 0.0 1.6 2 0 0 2 2 2 1 KIAA1430 homologue PH PF00169.29 PFH34421.1 - 0.0054 17.2 0.0 0.019 15.5 0.0 1.9 2 0 0 2 2 2 1 PH domain QRPTase_C PF01729.19 PFH34421.1 - 0.11 12.2 0.7 0.24 11.2 0.7 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF1811 PF08838.10 PFH34421.1 - 1.8 8.9 5.3 1.5 9.1 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) HAP1_N PF04849.13 PFH34421.1 - 4.4 6.4 30.4 0.64 9.2 2.7 2.5 3 0 0 3 3 3 0 HAP1 N-terminal conserved region Pribosyltran PF00156.27 PFH34423.1 - 1.7e-33 115.4 0.0 2.1e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 PFH34423.1 - 0.085 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase UPRTase PF14681.6 PFH34423.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase GAF PF01590.26 PFH34425.1 - 4.3e-18 66.2 0.4 2.9e-10 40.9 0.0 2.8 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 PFH34425.1 - 4.4e-13 49.7 0.0 1.3e-08 35.2 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 PFH34425.1 - 1.5e-10 41.5 0.0 5.8e-09 36.4 0.0 3.2 3 1 0 3 3 3 1 GAF domain Atg14 PF10186.9 PFH34425.1 - 0.057 12.5 4.6 0.097 11.7 4.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 PFH34425.1 - 0.075 13.1 0.9 0.14 12.3 0.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PAS PF00989.25 PFH34425.1 - 0.12 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 PAS fold DivIC PF04977.15 PFH34425.1 - 0.14 11.9 0.7 0.3 10.9 0.7 1.5 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 PFH34425.1 - 0.21 12.2 3.9 0.17 12.5 0.7 2.4 2 0 0 2 2 2 0 SlyX Rhomboid PF01694.22 PFH34426.1 - 2.3e-30 105.6 14.3 4e-30 104.8 14.3 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 PFH34426.1 - 0.088 13.4 0.7 0.088 13.4 0.7 2.2 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) ATG16 PF08614.11 PFH34427.1 - 6.8e-15 55.8 0.2 1.4e-14 54.9 0.2 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 PFH34427.1 - 7.7e-13 48.7 9.8 0.0094 16.8 0.0 6.4 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH34427.1 - 4.4e-07 30.1 0.4 0.023 15.0 0.0 4.1 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PFH34427.1 - 0.022 13.4 1.2 0.57 8.8 1.7 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PFH34427.1 - 0.14 11.0 0.0 1.1 8.1 0.0 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CENP-F_leu_zip PF10473.9 PFH34427.1 - 0.8 9.7 21.1 1.2 9.2 21.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PAN_1 PF00024.26 PFH34428.1 - 2.3e-23 81.9 24.3 2e-06 27.7 3.1 4.2 3 1 1 4 4 4 4 PAN domain PAN_4 PF14295.6 PFH34428.1 - 2e-14 53.2 21.2 7e-06 25.9 1.2 4.4 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.12 PFH34428.1 - 2.9e-05 23.8 13.1 0.29 11.0 0.3 4.3 4 0 0 4 4 4 3 PAN-like domain PAN_2 PF08276.11 PFH34428.1 - 0.0032 17.5 22.3 0.53 10.4 0.1 4.5 4 0 0 4 4 4 4 PAN-like domain MANEC PF07502.14 PFH34428.1 - 0.035 14.4 16.0 6.3 7.1 0.3 4.4 4 0 0 4 4 4 0 MANEC domain PAN_1 PF00024.26 PFH34429.1 - 1.1e-24 86.2 23.9 2.4e-07 30.6 2.6 4.2 2 1 2 4 4 4 4 PAN domain PAN_4 PF14295.6 PFH34429.1 - 8.4e-18 64.0 20.8 2.7e-06 27.2 0.7 4.5 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.12 PFH34429.1 - 6.6e-07 29.0 11.2 0.075 12.9 0.2 4.2 4 0 0 4 4 4 3 PAN-like domain PAN_2 PF08276.11 PFH34429.1 - 1.4e-05 25.1 23.0 0.65 10.2 4.1 4.9 5 0 0 5 5 5 4 PAN-like domain MANEC PF07502.14 PFH34429.1 - 0.044 14.1 19.9 2.9 8.2 0.8 4.5 4 0 0 4 4 4 0 MANEC domain zf-TRM13_CCCH PF11722.8 PFH34429.1 - 0.11 12.3 0.1 0.11 12.3 0.1 3.4 5 0 0 5 5 5 0 CCCH zinc finger in TRM13 protein PAN_1 PF00024.26 PFH34430.1 - 3.6e-26 90.9 20.0 6.1e-08 32.5 2.2 4.1 3 1 1 4 4 4 4 PAN domain PAN_4 PF14295.6 PFH34430.1 - 8.4e-19 67.2 19.4 2.2e-06 27.5 0.8 4.4 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.12 PFH34430.1 - 2.6e-09 36.8 10.0 0.011 15.5 0.1 4.3 4 0 0 4 4 4 4 PAN-like domain PAN_2 PF08276.11 PFH34430.1 - 2.3e-05 24.4 23.8 0.46 10.6 4.0 4.6 4 0 0 4 4 4 4 PAN-like domain MANEC PF07502.14 PFH34430.1 - 0.055 13.7 19.8 1.5 9.2 0.4 4.4 4 0 0 4 4 4 0 MANEC domain zf-TRM13_CCCH PF11722.8 PFH34430.1 - 0.1 12.4 0.1 0.1 12.4 0.1 3.4 5 0 0 5 5 5 0 CCCH zinc finger in TRM13 protein PAN_1 PF00024.26 PFH34431.1 - 4.6e-27 93.8 22.4 2.5e-07 30.6 2.7 4.1 3 1 1 4 4 4 4 PAN domain PAN_4 PF14295.6 PFH34431.1 - 9e-18 63.9 20.8 2.6e-06 27.2 0.7 4.4 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.12 PFH34431.1 - 4.2e-10 39.3 9.6 0.0074 16.1 0.1 4.3 4 0 0 4 4 4 4 PAN-like domain PAN_2 PF08276.11 PFH34431.1 - 9.3e-05 22.5 23.9 0.63 10.2 4.1 4.6 4 0 0 4 4 4 4 PAN-like domain MANEC PF07502.14 PFH34431.1 - 0.081 13.2 21.4 1.3 9.3 1.4 4.4 4 0 0 4 4 4 0 MANEC domain PAN_1 PF00024.26 PFH34432.1 - 2.1e-25 88.5 21.7 8.1e-08 32.1 0.7 4.1 3 1 1 4 4 4 4 PAN domain PAN_4 PF14295.6 PFH34432.1 - 9.1e-19 67.1 20.3 7.1e-07 29.0 1.1 4.4 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.12 PFH34432.1 - 2.7e-07 30.3 12.6 0.032 14.0 0.2 4.3 4 0 0 4 4 4 3 PAN-like domain PAN_2 PF08276.11 PFH34432.1 - 1.4e-05 25.1 22.5 0.12 12.5 2.4 4.6 4 0 0 4 4 4 4 PAN-like domain MANEC PF07502.14 PFH34432.1 - 0.0008 19.6 17.7 0.73 10.1 0.2 4.4 4 0 0 4 4 4 3 MANEC domain YxiJ PF14176.6 PFH34432.1 - 0.049 14.1 0.0 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 YxiJ-like protein Pkinase PF00069.25 PFH34433.1 - 3.7e-21 75.7 0.0 2.7e-10 40.1 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34433.1 - 0.00049 19.5 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DEAD PF00270.29 PFH34434.1 - 1.3e-09 38.0 0.0 9.1e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH34434.1 - 1.6e-07 31.6 0.0 3.2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain KBP_C PF12309.8 PFH34436.1 - 1.1e-51 176.5 4.5 1.5e-51 176.0 0.4 2.4 2 0 0 2 2 2 1 KIF-1 binding protein C terminal COX1 PF00115.20 PFH34436.1 - 0.00012 21.1 1.3 0.0002 20.4 1.3 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Pkinase PF00069.25 PFH34437.1 - 3.7e-06 26.5 0.3 0.34 10.2 0.0 4.7 5 0 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34437.1 - 0.0071 15.6 0.0 1 8.6 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase NAM-associated PF14303.6 PFH34437.1 - 0.88 10.3 0.0 0.88 10.3 0.0 17.7 14 5 4 18 18 18 0 No apical meristem-associated C-terminal domain MFS_1 PF07690.16 PFH34438.1 - 3.9e-24 85.2 35.8 1.2e-17 63.9 4.1 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 PFH34438.1 - 1.3e-15 57.2 6.3 7.3e-11 41.6 0.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 PFH34438.1 - 6.8e-12 44.5 12.5 6.5e-07 28.0 0.0 4.1 3 2 2 5 5 5 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 PFH34438.1 - 0.0059 15.5 5.9 1.4 7.7 3.9 2.2 2 0 0 2 2 2 2 MFS_1 like family Phage_holin_3_6 PF07332.11 PFH34441.1 - 0.0041 17.2 0.2 0.0063 16.5 0.2 1.3 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Spec3 PF15795.5 PFH34441.1 - 2.1 9.0 14.4 0.51 10.9 6.7 2.3 1 1 1 2 2 2 0 Ectodermal ciliogenesis protein RRM_1 PF00076.22 PFH34442.1 - 2.6e-52 174.5 0.0 4e-16 58.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH34442.1 - 1.8e-09 37.6 0.1 0.23 11.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif RRM_5 PF13893.6 PFH34442.1 - 2.2e-08 33.7 0.0 0.1 12.2 0.0 3.5 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 PFH34442.1 - 7.2e-08 32.4 3.6 1.3e-07 31.6 3.6 1.4 1 0 0 1 1 1 1 WW domain RNA_bind PF08675.11 PFH34442.1 - 7e-05 22.8 0.0 0.0029 17.6 0.0 2.9 3 0 0 3 3 3 1 RNA binding domain PHM7_cyt PF14703.6 PFH34442.1 - 0.00012 22.4 0.5 2.2 8.5 0.0 4.0 3 2 1 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter BRAP2 PF07576.12 PFH34442.1 - 0.0004 20.5 0.0 2.9 8.2 0.0 3.0 3 0 0 3 3 3 2 BRCA1-associated protein 2 Nup35_RRM PF05172.13 PFH34442.1 - 0.0018 18.2 0.0 0.19 11.7 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 PFH34443.1 - 2.4e-55 187.8 0.0 4.5e-55 186.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34443.1 - 1.2e-32 113.2 0.2 3.3e-24 85.6 0.1 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 PFH34443.1 - 3.3e-06 26.6 0.0 0.00011 21.6 0.0 2.3 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PFH34443.1 - 0.00016 20.6 1.6 0.00032 19.6 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 PFH34443.1 - 0.00026 20.7 0.3 0.48 10.0 0.0 2.6 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 PFH34443.1 - 0.0006 19.5 0.2 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 PFH34443.1 - 0.015 15.3 0.0 0.015 15.3 0.0 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 PFH34443.1 - 0.015 14.7 0.1 0.015 14.7 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Neur_chan_memb PF02932.16 PFH34443.1 - 0.095 12.7 3.3 0.17 11.9 3.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Kinase-PolyVal PF18762.1 PFH34443.1 - 0.15 12.0 0.2 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins ANAPC4_WD40 PF12894.7 PFH34447.1 - 8.9e-12 45.1 0.0 0.014 15.7 0.0 5.1 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PFH34447.1 - 1.9e-11 44.3 7.2 0.0061 17.4 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat IKI3 PF04762.12 PFH34447.1 - 0.016 13.2 0.0 1 7.3 0.0 2.1 2 0 0 2 2 2 0 IKI3 family Chromo PF00385.24 PFH34451.1 - 9.4e-08 31.9 1.4 2e-07 30.8 1.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Merozoite_SPAM PF07133.11 PFH34451.1 - 1.2 9.1 16.3 2.5 8.1 16.3 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DEAD PF00270.29 PFH34452.1 - 1e-35 123.1 0.0 5.1e-35 120.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH34452.1 - 1.9e-18 66.8 0.0 4.7e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH34452.1 - 2.1e-08 34.4 0.0 3.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PFH34452.1 - 0.0004 20.7 0.4 0.0027 18.0 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PFH34452.1 - 0.18 12.1 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tme5_EGF_like PF09064.10 PFH34453.1 - 0.26 11.2 32.2 4.2 7.4 0.0 8.4 7 2 1 8 8 8 0 Thrombomodulin like fifth domain, EGF-like cEGF PF12662.7 PFH34453.1 - 1.8 8.6 0.0 1.8 8.6 0.0 11.5 11 2 0 11 11 11 0 Complement Clr-like EGF-like TRAPPC9-Trs120 PF08626.11 PFH34455.1 - 2.6e-18 64.9 0.0 1.4e-08 32.7 0.0 5.2 5 0 0 5 5 5 5 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Glyco_tran_28_C PF04101.16 PFH34456.1 - 8.8e-16 58.3 0.0 2e-11 44.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain ORC6 PF05460.13 PFH34456.1 - 2.2 7.5 4.8 5.5 6.2 4.8 1.6 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ANAPC4_WD40 PF12894.7 PFH34457.1 - 0.00098 19.4 0.0 0.0049 17.1 0.0 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PFH34457.1 - 0.027 13.5 0.0 0.076 12.0 0.0 1.6 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4633 PF15464.6 PFH34457.1 - 4.9 7.3 8.2 2.6 8.2 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) FAT PF02259.23 PFH34459.1 - 9.3e-18 64.5 0.4 1.5e-17 63.9 0.4 1.3 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 PFH34459.1 - 7.5e-17 62.0 0.0 7e-16 58.8 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RRM_1 PF00076.22 PFH34461.1 - 2.5e-10 40.0 0.0 8.8e-05 22.2 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH34461.1 - 0.1 12.7 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif SbcCD_C PF13558.6 PFH34461.1 - 0.24 11.7 4.0 4.5 7.6 0.1 3.2 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit gag-asp_proteas PF13975.6 PFH34463.1 - 0.0019 18.7 0.0 0.0079 16.7 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 PFH34463.1 - 0.02 15.5 0.0 0.038 14.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 PFH34463.1 - 0.11 12.8 0.0 0.43 10.9 0.0 2.0 2 1 0 2 2 2 0 Retroviral aspartyl protease DUF4460 PF14687.6 PFH34464.1 - 2.5e-08 34.0 0.0 6.7e-07 29.3 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4460) DUF4461 PF14688.6 PFH34464.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) DUF3450 PF11932.8 PFH34465.1 - 0.28 10.4 12.7 0.036 13.4 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TarH PF02203.15 PFH34465.1 - 4.1 7.3 15.1 0.027 14.4 4.5 2.2 2 0 0 2 2 2 0 Tar ligand binding domain homologue DUF1387 PF07139.11 PFH34465.1 - 6.3 6.4 9.8 0.43 10.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1387) XPG_I PF00867.18 PFH34466.1 - 8e-26 90.2 0.0 2.6e-25 88.6 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 PFH34466.1 - 2.4e-25 89.0 0.0 5.5e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain HHH_2 PF12826.7 PFH34466.1 - 0.085 13.0 0.0 0.37 10.9 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif zf_CCCH_4 PF18345.1 PFH34467.1 - 9.9e-20 69.9 53.9 1e-06 28.6 4.0 5.4 5 0 0 5 5 5 4 Zinc finger domain zf-CCCH PF00642.24 PFH34467.1 - 8.2e-19 67.0 40.6 1e-05 25.3 4.2 5.7 5 1 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PFH34467.1 - 1.1e-13 50.6 45.0 7.9e-08 31.9 5.3 4.9 5 0 0 5 5 5 3 CCCH-type zinc finger Torus PF16131.5 PFH34467.1 - 2.2e-13 50.9 19.2 0.001 19.8 1.4 5.2 4 1 1 5 5 5 4 Torus domain zf-CCCH_2 PF14608.6 PFH34467.1 - 6.9e-09 35.9 41.2 0.0068 16.8 4.1 5.1 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 PFH34467.1 - 2.5e-08 34.1 20.2 0.01 16.1 0.1 4.7 4 1 1 5 5 5 4 Zinc-finger containing family Rhomboid PF01694.22 PFH34469.1 - 2.5e-27 95.7 11.1 5.6e-27 94.6 11.1 1.6 1 0 0 1 1 1 1 Rhomboid family Med3 PF11593.8 PFH34469.1 - 0.37 9.9 2.2 0.54 9.4 2.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Herpes_TAF50 PF03326.13 PFH34469.1 - 2.3 6.8 7.1 3.3 6.3 7.1 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DNA_pol_E_B PF04042.16 PFH34470.1 - 1.1e-12 47.8 0.2 2e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SAG PF04092.13 PFH34471.1 - 4.4e-41 140.7 2.4 1.7e-21 77.4 0.3 2.1 2 0 0 2 2 2 2 SRS domain Peptidase_S8 PF00082.22 PFH34472.1 - 3e-42 144.9 3.1 3e-42 144.9 3.1 2.5 2 0 0 2 2 2 2 Subtilase family SUB1_ProdP9 PF18213.1 PFH34472.1 - 0.2 11.6 0.1 0.41 10.5 0.1 1.4 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 MMR_HSR1 PF01926.23 PFH34473.1 - 7.7e-16 58.2 0.0 1.6e-14 53.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase TrmE_N PF10396.9 PFH34473.1 - 6.6e-15 55.4 0.0 9.3e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 PFH34473.1 - 3.9e-14 53.3 0.0 2.8e-13 50.5 0.0 2.0 1 1 0 1 1 1 1 MnmE helical domain FeoB_N PF02421.18 PFH34473.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PFH34473.1 - 0.0013 18.8 0.0 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 PFH34473.1 - 0.063 13.2 0.0 0.44 10.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 PFH34473.1 - 0.12 12.6 1.1 0.5 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain SnoaL_2 PF12680.7 PFH34473.1 - 2.2 9.0 5.7 37 5.0 0.1 3.5 4 0 0 4 4 4 0 SnoaL-like domain LapA_dom PF06305.11 PFH34474.1 - 0.1 12.4 0.9 0.72 9.7 0.3 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain CTP_transf_3 PF02348.19 PFH34474.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Pro_isomerase PF00160.21 PFH34475.1 - 9.6e-24 84.4 0.0 1.3e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 PFH34480.1 - 4.2e-40 137.8 0.0 3.1e-19 69.4 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34480.1 - 6e-11 42.1 0.0 2.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase eIF2A PF08662.11 PFH34481.1 - 2.9e-47 161.1 0.0 6.2e-41 140.4 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A GYF PF02213.16 PFH34481.1 - 2.2e-16 59.3 0.0 4.3e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 GYF domain SOR_SNZ PF01680.17 PFH34481.1 - 0.055 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 SOR/SNZ family WD40 PF00400.32 PFH34481.1 - 0.093 13.6 0.8 39 5.3 0.0 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat NEL PF14496.6 PFH34481.1 - 0.12 11.7 1.1 0.3 10.5 1.1 1.6 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting BLOC1_2 PF10046.9 PFH34481.1 - 0.21 11.9 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PHD PF00628.29 PFH34482.1 - 3.4e-10 39.7 3.7 3.4e-10 39.7 3.7 2.7 3 0 0 3 3 2 1 PHD-finger zf-RING_2 PF13639.6 PFH34482.1 - 8.7e-08 32.4 9.0 8.7e-08 32.4 9.0 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 PFH34482.1 - 4.4e-06 26.5 7.5 1.4e-05 24.8 7.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PFH34482.1 - 6.4e-06 25.9 4.4 3.2e-05 23.7 4.4 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PFH34482.1 - 1.7e-05 24.6 7.8 5.6e-05 22.9 7.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH34482.1 - 0.00017 21.5 7.7 0.00081 19.3 7.7 2.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PFH34482.1 - 0.0039 17.0 6.8 0.016 15.0 6.8 2.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PFH34482.1 - 0.013 15.5 6.3 0.034 14.2 3.8 2.7 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_11 PF17123.5 PFH34482.1 - 0.027 14.2 5.6 0.071 12.9 5.6 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-PHD-like PF15446.6 PFH34482.1 - 0.044 13.4 1.1 0.14 11.8 1.1 1.9 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-rbx1 PF12678.7 PFH34482.1 - 0.085 13.2 16.3 0.016 15.5 10.4 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 PFH34482.1 - 0.16 11.8 10.5 0.041 13.7 6.2 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ADK_lid PF05191.14 PFH34482.1 - 0.2 11.7 1.9 9.2 6.3 0.0 3.9 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-RING_10 PF16685.5 PFH34482.1 - 0.21 11.7 3.4 0.66 10.2 3.4 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 PFH34482.1 - 0.35 11.0 10.7 0.74 9.9 3.4 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger MACPF PF01823.19 PFH34483.1 - 5.1e-46 157.4 0.0 1.1e-45 156.3 0.0 1.6 1 0 0 1 1 1 1 MAC/Perforin domain CWC25 PF12542.8 PFH34484.1 - 2.2e-13 51.0 0.0 2.2e-13 51.0 0.0 4.2 4 1 0 4 4 4 1 Pre-mRNA splicing factor Pkinase PF00069.25 PFH34485.1 - 3.9e-33 114.9 0.0 1e-12 48.0 0.0 4.9 4 1 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34485.1 - 1.1e-16 60.9 0.0 9.9e-09 34.8 0.0 4.2 4 1 0 4 4 4 2 Protein tyrosine kinase Kdo PF06293.14 PFH34485.1 - 0.032 13.6 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PFH34485.1 - 0.079 12.3 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Kinase-like YTH PF04146.15 PFH34486.1 - 4.4e-34 117.8 0.0 1.1e-33 116.5 0.0 1.7 1 1 0 1 1 1 1 YT521-B-like domain SNARE PF05739.19 PFH34487.1 - 1.3e-06 28.3 0.8 4.2e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 PFH34487.1 - 1.2e-05 25.6 3.2 1.2e-05 25.6 3.2 2.3 2 0 0 2 2 2 1 Syntaxin-like protein Synaptobrevin PF00957.21 PFH34487.1 - 0.065 13.0 0.7 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 Synaptobrevin Exonuc_VII_L PF02601.15 PFH34487.1 - 0.22 11.0 4.8 3.6 7.1 0.4 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit SPACA9 PF15120.6 PFH34487.1 - 0.26 11.1 4.0 1.9 8.2 0.3 2.4 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 DUF892 PF05974.12 PFH34487.1 - 0.38 10.8 8.6 0.12 12.3 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF892) Trns_repr_metal PF02583.17 PFH34487.1 - 2 8.8 7.2 1.6 9.2 1.9 2.9 2 1 1 3 3 3 0 Metal-sensitive transcriptional repressor CorA PF01544.18 PFH34487.1 - 4.2 6.6 11.3 0.62 9.3 5.3 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 PFH34487.1 - 8.5 6.4 10.1 7.4 6.6 1.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_L2_C PF03947.18 PFH34488.1 - 1.5e-45 154.5 5.1 2.6e-45 153.7 5.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 PFH34488.1 - 3.3e-19 68.6 0.2 8.6e-19 67.3 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF4672 PF15716.5 PFH34488.1 - 0.25 11.0 1.1 0.38 10.3 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) GCN5L1 PF06320.13 PFH34491.1 - 0.00042 20.4 1.0 0.00042 20.4 1.0 2.2 3 0 0 3 3 3 1 GCN5-like protein 1 (GCN5L1) WD-3 PF09765.9 PFH34491.1 - 0.42 9.9 4.5 1.1 8.6 4.5 1.6 1 1 0 1 1 1 0 WD-repeat region Kinase-like PF14531.6 PFH34493.1 - 1.2e-09 37.9 0.0 1.4e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH34493.1 - 4e-08 32.9 0.0 4.5e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34493.1 - 1.9e-05 24.1 0.0 1.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DDOST_48kD PF03345.14 PFH34494.1 - 9.4e-72 242.1 0.0 7.1e-64 216.2 0.0 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta Myb_DNA-bind_7 PF15963.5 PFH34496.1 - 3.5e-21 74.9 0.1 1.1e-20 73.2 0.1 1.9 1 0 0 1 1 1 1 Myb DNA-binding like HMG_box_2 PF09011.10 PFH34496.1 - 1.9e-12 47.6 12.6 2.9e-08 34.2 2.8 2.7 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 PFH34496.1 - 1.6e-11 44.4 7.0 2.9e-07 30.8 0.7 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box Myb_DNA-binding PF00249.31 PFH34496.1 - 0.00068 19.8 1.1 0.0027 17.8 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain TFIIF_alpha PF05793.12 PFH34496.1 - 3.4 6.1 37.2 17 3.8 37.2 2.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ABC1 PF03109.16 PFH34497.1 - 3.4e-30 104.7 0.0 6.2e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RabGAP-TBC PF00566.18 PFH34499.1 - 5.3e-46 157.0 0.3 1.1e-45 155.9 0.3 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FAM184 PF15665.5 PFH34500.1 - 3.7e-09 36.7 25.7 3.7e-09 36.7 25.7 7.6 2 2 5 7 7 7 2 Family with sequence similarity 184, A and B DUF2443 PF10398.9 PFH34500.1 - 0.047 13.7 0.9 1.3 9.2 0.1 4.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) Surfac_D-trimer PF09006.11 PFH34500.1 - 0.38 10.7 1.8 5.9 6.9 0.0 3.8 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation ANAPC2 PF08672.11 PFH34500.1 - 1 9.9 6.5 4.9 7.7 0.1 4.6 5 0 0 5 5 5 0 Anaphase promoting complex (APC) subunit 2 Isy1 PF06246.12 PFH34502.1 - 9.8e-78 261.2 7.2 1.3e-77 260.9 7.2 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Kinase-like PF14531.6 PFH34503.1 - 6.7e-36 124.1 0.0 1.3e-33 116.6 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH34503.1 - 7.8e-07 28.7 0.0 0.033 13.6 0.0 3.2 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34503.1 - 0.0045 16.3 0.1 0.0081 15.5 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase CutC PF03932.14 PFH34503.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 CutC family Kinase-like PF14531.6 PFH34504.1 - 7.4e-39 133.8 0.0 1.4e-36 126.3 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH34504.1 - 1.3e-07 31.3 0.0 0.0046 16.4 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34504.1 - 0.00083 18.7 0.1 0.0017 17.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PFH34504.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PFH34505.1 - 7.4e-39 133.8 0.0 1.4e-36 126.3 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH34505.1 - 1.3e-07 31.3 0.0 0.0046 16.4 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34505.1 - 0.00083 18.7 0.1 0.0017 17.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PFH34505.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PFH34506.1 - 7.4e-39 133.8 0.0 1.4e-36 126.3 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH34506.1 - 1.3e-07 31.3 0.0 0.0046 16.4 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34506.1 - 0.00083 18.7 0.1 0.0017 17.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PFH34506.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PFH34507.1 - 2.5e-38 132.1 0.0 4.7e-36 124.6 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH34507.1 - 1.5e-07 31.1 0.0 0.0051 16.2 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34507.1 - 0.00094 18.5 0.1 0.0019 17.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PFH34507.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PFH34508.1 - 7.3e-39 133.8 0.0 1.7e-36 126.1 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH34508.1 - 2.7e-07 30.2 0.0 0.007 15.8 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34508.1 - 0.0015 17.9 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PFH34508.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TerB PF05099.13 PFH34509.1 - 0.06 13.3 0.4 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 Tellurite resistance protein TerB DUF3119 PF11317.8 PFH34510.1 - 0.14 12.4 0.1 0.22 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3119) COX4_pro_2 PF07835.12 PFH34510.1 - 0.64 10.2 1.9 1.1 9.4 1.9 1.3 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV Isy1 PF06246.12 PFH34511.1 - 3.8e-74 249.5 6.2 4.9e-74 249.1 6.2 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Kinase-like PF14531.6 PFH34512.1 - 3.6e-38 131.5 0.0 3.2e-36 125.1 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Pkinase PF00069.25 PFH34512.1 - 3.3e-12 46.3 0.0 2.1e-07 30.6 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34512.1 - 1.8e-05 24.2 0.1 3.5e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH34512.1 - 0.013 15.4 0.7 0.013 15.4 0.7 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 PFH34512.1 - 0.033 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 PFH34512.1 - 0.034 13.5 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PFH34512.1 - 0.16 10.7 0.0 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 PFH34513.1 - 0.12 11.6 0.0 0.29 10.4 0.0 1.5 1 1 1 2 2 2 0 Kinase-like Helicase_C PF00271.31 PFH34515.1 - 1.5e-16 60.7 0.0 3.5e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PFH34515.1 - 1.2e-10 41.4 0.0 1.1e-06 28.5 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase FHA PF00498.26 PFH34516.1 - 3.6e-14 52.8 0.2 5.4e-07 29.9 0.4 2.4 2 0 0 2 2 2 2 FHA domain zf-C3HC4_4 PF15227.6 PFH34516.1 - 5.6e-08 32.8 9.2 1.4e-07 31.5 9.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 PFH34516.1 - 2.6e-07 30.4 8.3 5.9e-07 29.2 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PFH34516.1 - 8.6e-07 28.7 11.2 1.7e-06 27.7 11.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PFH34516.1 - 8.8e-07 29.2 11.0 2.1e-06 27.9 11.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PFH34516.1 - 1.7e-06 27.9 10.1 4.5e-06 26.6 10.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PFH34516.1 - 8.4e-06 25.6 10.7 1.6e-05 24.6 10.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 PFH34516.1 - 4.8e-05 23.4 5.1 9.4e-05 22.5 5.1 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 PFH34516.1 - 0.00013 21.7 9.3 0.00061 19.6 8.5 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 PFH34516.1 - 0.00017 21.4 2.9 0.00038 20.3 2.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 PFH34516.1 - 0.00048 20.0 10.5 0.0012 18.7 10.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 PFH34516.1 - 0.015 15.1 3.6 0.042 13.7 3.6 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 PFH34516.1 - 0.029 14.6 7.1 0.078 13.3 7.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zinc_ribbon_12 PF11331.8 PFH34516.1 - 0.81 9.5 3.9 2.3 8.1 3.9 1.8 1 0 0 1 1 1 0 Probable zinc-ribbon domain DNA_pol_phi PF04931.13 PFH34517.1 - 1.8 6.6 7.7 0.27 9.3 3.0 1.8 2 0 0 2 2 2 0 DNA polymerase phi Striatin PF08232.12 PFH34517.1 - 3.7 8.1 12.6 0.85 10.2 3.5 2.8 2 0 0 2 2 2 0 Striatin family Kelch_3 PF13415.6 PFH34518.1 - 3.3e-30 103.8 11.7 3e-07 30.5 0.1 6.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 PFH34518.1 - 6.5e-28 96.5 13.7 9.2e-07 28.8 0.0 5.6 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PFH34518.1 - 2.8e-26 91.0 4.6 7.2e-09 35.4 0.5 5.7 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 PFH34518.1 - 3.4e-24 84.3 14.0 3.3e-05 24.0 0.0 6.4 4 2 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 PFH34518.1 - 3.5e-22 77.7 12.9 1.7e-06 27.5 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 PFH34518.1 - 2.6e-17 62.0 5.9 1.9e-06 27.6 0.4 4.7 4 0 0 4 4 4 4 Kelch motif OHA PF14418.6 PFH34519.1 - 2.1e-12 46.7 0.0 4.8e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 OST-HTH Associated domain OST-HTH PF12872.7 PFH34519.1 - 9.4e-05 22.2 0.2 0.00036 20.3 0.0 2.1 3 0 0 3 3 3 1 OST-HTH/LOTUS domain Herpes_gE PF02480.16 PFH34521.1 - 0.0083 14.9 0.1 0.072 11.8 0.1 1.9 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E CD34_antigen PF06365.12 PFH34521.1 - 0.036 13.6 0.1 0.05 13.2 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF3318 PF11780.8 PFH34521.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) RRN3 PF05327.11 PFH34522.1 - 0.092 11.3 0.0 0.092 11.3 0.0 3.4 3 1 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 NatB_MDM20 PF09797.9 PFH34523.1 - 8.1e-15 54.6 7.9 1.2e-07 31.1 0.1 3.2 3 0 0 3 3 3 2 N-acetyltransferase B complex (NatB) non catalytic subunit YceD PF02620.17 PFH34523.1 - 0.08 13.1 1.0 0.22 11.7 0.1 2.2 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD RAP PF08373.10 PFH34524.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 RAP domain VKOR PF07884.14 PFH34525.1 - 2.3e-17 63.3 13.9 2.7e-17 63.1 13.9 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family AP2 PF00847.20 PFH34526.1 - 3.2e-08 33.7 2.9 3.1e-07 30.5 0.6 2.5 2 0 0 2 2 2 1 AP2 domain Phage_int_SAM_1 PF02899.17 PFH34526.1 - 0.22 11.9 0.4 0.88 9.9 0.4 2.0 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Got1 PF04178.12 PFH34527.1 - 3.4e-28 98.3 8.0 4.4e-28 98.0 8.0 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family AP2 PF00847.20 PFH34528.1 - 7.7e-09 35.7 2.6 3.8e-07 30.2 1.0 2.4 1 1 1 2 2 2 2 AP2 domain Herpes_US12 PF05363.12 PFH34528.1 - 1.8 9.3 5.7 1.2 9.9 0.2 3.4 3 0 0 3 3 3 0 Herpesvirus US12 family Chorein_N PF12624.7 PFH34529.1 - 7e-18 64.8 0.0 1.4e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Ribosomal_L44 PF00935.19 PFH34530.1 - 5.8e-36 122.8 13.0 7.6e-36 122.4 13.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 MRP-S28 PF10213.9 PFH34531.1 - 7.2e-11 42.6 0.0 1.8e-10 41.3 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein EXOSC1 PF10447.9 PFH34532.1 - 1.2e-18 67.7 0.4 6.3e-12 46.1 0.1 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 PFH34532.1 - 2e-09 37.1 0.3 2e-09 37.1 0.3 1.7 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region CCDC144C PF14915.6 PFH34534.1 - 0.062 12.4 0.0 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region NAD_binding_4 PF07993.12 PFH34535.1 - 1.5e-60 204.5 0.0 2.4e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 PFH34535.1 - 1.3e-14 54.1 0.1 3e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 PFH34535.1 - 5.2e-12 45.5 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase 3Beta_HSD PF01073.19 PFH34535.1 - 2.2e-08 33.4 0.0 7.5e-07 28.4 0.1 2.7 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PFH34535.1 - 9.7e-08 31.8 0.0 2.1e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PFH34535.1 - 0.00035 20.1 0.0 0.25 10.7 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 PFH34535.1 - 0.091 11.9 0.1 1.8 7.6 0.1 2.2 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 PFH34535.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RRM_1 PF00076.22 PFH34536.1 - 1e-53 179.0 0.0 2e-17 62.7 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH34536.1 - 2.5e-10 40.3 0.0 0.00032 20.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif RRM_5 PF13893.6 PFH34536.1 - 7.7e-07 28.8 0.0 0.046 13.3 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 PFH34536.1 - 0.017 15.1 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 0 RNA binding domain RRM_occluded PF16842.5 PFH34536.1 - 0.19 11.6 0.0 31 4.5 0.1 3.2 3 0 0 3 3 3 0 Occluded RNA-recognition motif Popeye PF04831.13 PFH34537.1 - 4.1e-09 36.7 0.0 1.7e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Popeye protein conserved region cNMP_binding PF00027.29 PFH34537.1 - 0.033 14.3 0.1 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain zf-C3HC4_2 PF13923.6 PFH34538.1 - 1.9e-07 30.8 12.3 1.9e-07 30.8 12.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PFH34538.1 - 3.8e-06 27.1 11.6 3.8e-06 27.1 11.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 PFH34538.1 - 1.8e-05 24.5 12.5 1.8e-05 24.5 12.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PFH34538.1 - 2e-05 24.4 12.2 2e-05 24.4 12.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PFH34538.1 - 0.00044 20.5 4.1 0.0013 19.0 4.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PFH34538.1 - 0.0013 18.6 13.7 0.0013 18.6 13.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain LON_substr_bdg PF02190.16 PFH34538.1 - 0.0016 18.4 0.0 0.0055 16.6 0.0 1.7 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_4 PF15227.6 PFH34538.1 - 0.0042 17.2 13.9 0.0042 17.2 13.9 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.15 PFH34538.1 - 0.0083 16.3 0.0 0.029 14.5 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-RING_UBOX PF13445.6 PFH34538.1 - 0.0093 16.0 15.4 0.0093 16.0 15.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PFH34538.1 - 0.023 14.5 14.7 0.055 13.3 14.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 PFH34538.1 - 0.28 11.4 16.4 0.069 13.3 11.6 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 AlaDh_PNT_C PF01262.21 PFH34540.1 - 1.4e-55 187.9 11.5 2.5e-54 183.8 11.5 2.3 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 PFH34540.1 - 4.2e-38 130.7 0.0 9.9e-38 129.5 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DEFB136 PF17333.2 PFH34540.1 - 0.004 17.1 1.7 0.004 17.1 1.7 3.3 4 0 0 4 4 4 1 Beta defensin 136 Pyr_redox_2 PF07992.14 PFH34540.1 - 0.0056 16.0 0.5 0.0094 15.2 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF779 PF05610.11 PFH34540.1 - 0.0064 16.7 0.0 0.028 14.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF779) NAD_binding_7 PF13241.6 PFH34540.1 - 0.0074 16.7 0.1 0.022 15.2 0.1 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.27 PFH34540.1 - 0.065 13.8 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FucT_N PF18025.1 PFH34540.1 - 0.07 13.6 1.1 0.35 11.4 0.0 2.5 3 0 0 3 3 3 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain FAD_oxidored PF12831.7 PFH34540.1 - 1.1 8.5 5.1 5.7 6.2 4.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase GN3L_Grn1 PF08701.11 PFH34541.1 - 1.2e-20 73.3 10.8 1.2e-20 73.3 10.8 2.7 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 PFH34541.1 - 3.3e-16 59.4 0.1 1.5e-14 54.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PFH34541.1 - 1.9e-09 37.2 0.1 4e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PFH34541.1 - 0.00016 21.6 0.1 0.023 14.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 PFH34541.1 - 0.00043 19.9 0.0 0.14 11.7 0.0 3.2 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 PFH34541.1 - 0.0014 18.7 0.7 2 8.4 0.1 3.4 3 0 0 3 3 3 1 Dynamin family SRPRB PF09439.10 PFH34541.1 - 0.024 14.0 0.0 0.082 12.3 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 PFH34541.1 - 0.054 13.9 0.1 0.054 13.9 0.1 3.7 2 2 1 3 3 3 0 AAA ATPase domain cobW PF02492.19 PFH34541.1 - 0.17 11.5 0.1 3 7.4 0.0 2.6 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 PFH34541.1 - 0.17 10.8 1.6 0.24 10.4 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB UPF0239 PF06783.11 PFH34541.1 - 0.27 11.5 4.8 3.1 8.0 0.2 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) Kelch_5 PF13854.6 PFH34542.1 - 1.9e-08 34.1 0.1 0.0017 18.3 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 PFH34542.1 - 8.6e-05 22.5 5.2 0.045 13.8 0.1 5.5 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_1 PF01344.25 PFH34542.1 - 0.0082 15.7 0.1 16 5.1 0.0 3.7 3 0 0 3 3 3 2 Kelch motif UPF0203 PF05254.12 PFH34543.1 - 6.2e-16 58.4 1.4 8e-16 58.0 1.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 PFH34543.1 - 0.038 14.4 0.9 0.099 13.0 0.9 1.6 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 PFH34543.1 - 0.82 9.7 3.4 1.2 9.2 0.7 2.1 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3228 PF11539.8 PFH34544.1 - 1.7e-80 269.1 0.0 1.9e-80 269.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) ANAPC10 PF03256.16 PFH34545.1 - 8.5e-35 120.1 0.0 1.3e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 PFH34545.1 - 0.033 14.3 0.1 0.074 13.2 0.1 1.6 2 0 0 2 2 2 0 F5/8 type C domain UPF0054 PF02130.17 PFH34546.1 - 5.7e-20 71.4 0.0 1.8e-19 69.8 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized protein family UPF0054 ACPS PF01648.20 PFH34546.1 - 5.6e-05 23.2 0.0 0.00027 21.1 0.0 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 PFH34546.1 - 0.021 15.0 3.4 0.021 14.9 0.2 2.6 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain DUF2207 PF09972.9 PFH34547.1 - 0.012 14.4 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HEAT PF02985.22 PFH34547.1 - 0.41 11.0 2.4 1.5 9.3 0.5 2.4 2 0 0 2 2 2 0 HEAT repeat CRAL_TRIO PF00650.20 PFH34548.1 - 1.7e-27 96.1 0.0 2.7e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PFH34548.1 - 2.5e-05 24.4 0.0 4.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PFH34548.1 - 0.00041 20.5 0.1 0.00086 19.4 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DnaJ PF00226.31 PFH34549.1 - 6.1e-20 71.1 0.6 8.2e-13 48.3 0.0 3.3 2 0 0 2 2 2 2 DnaJ domain Myb_DNA-binding PF00249.31 PFH34549.1 - 1.4e-15 57.2 6.5 1e-07 32.1 0.0 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PFH34549.1 - 1.3e-09 38.1 0.8 0.0016 18.7 0.0 4.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain CLN3 PF02487.17 PFH34549.1 - 0.53 9.3 5.4 1.2 8.2 5.4 1.5 1 0 0 1 1 1 0 CLN3 protein DUF778 PF05608.12 PFH34549.1 - 3.9 7.8 5.8 12 6.2 5.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF778) CPW_WPC PF09717.10 PFH34550.1 - 7.1e-49 164.6 22.1 2.4e-15 57.2 3.4 4.1 3 1 1 4 4 4 4 Plasmodium falciparum domain of unknown function (CPW_WPC) Utp12 PF04003.12 PFH34551.1 - 5.5e-08 33.1 1.8 9.7e-08 32.3 1.8 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Prefoldin PF02996.17 PFH34552.1 - 7.7e-12 45.2 5.3 1.4e-11 44.3 0.2 2.1 2 0 0 2 2 2 1 Prefoldin subunit DUF1367 PF07105.11 PFH34552.1 - 0.12 12.0 0.1 0.25 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1367) Nif11 PF07862.11 PFH34552.1 - 5.1 7.5 6.1 30 5.0 1.0 3.3 3 1 0 3 3 3 0 Nif11 domain TFIIE_beta PF02186.15 PFH34553.1 - 0.0019 18.4 0.1 0.0038 17.5 0.1 1.4 1 0 0 1 1 1 1 TFIIE beta subunit core domain Mg_trans_NIPA PF05653.14 PFH34554.1 - 1.2e-16 60.7 18.0 1.2e-16 60.7 18.0 1.7 1 1 1 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 PFH34554.1 - 0.0029 17.8 7.8 0.0029 17.8 7.8 3.2 2 2 2 4 4 4 2 EamA-like transporter family UPF0242 PF06785.11 PFH34554.1 - 0.024 14.8 0.2 0.092 12.8 0.0 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3671 PF12420.8 PFH34554.1 - 0.25 11.4 0.9 0.95 9.6 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function Alkyl_sulf_dimr PF14863.6 PFH34555.1 - 1.7e-39 135.4 0.2 2.7e-39 134.8 0.2 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 PFH34555.1 - 5.9e-18 65.6 0.2 2e-17 63.9 0.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 PFH34555.1 - 7.2e-08 32.8 0.0 1.5e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2 PF02036.17 PFH34555.1 - 1.7e-07 31.7 0.0 1.4e-06 28.7 0.0 2.5 2 1 1 3 3 3 1 SCP-2 sterol transfer family Lactamase_B_2 PF12706.7 PFH34555.1 - 0.0045 16.5 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MPP6 PF10175.9 PFH34555.1 - 0.2 12.1 0.3 0.45 11.0 0.3 1.5 1 0 0 1 1 1 0 M-phase phosphoprotein 6 Phage_GP20 PF06810.11 PFH34556.1 - 0.0011 18.7 20.9 0.0037 17.1 6.0 2.3 2 0 0 2 2 2 2 Phage minor structural protein GP20 Baculo_PEP_C PF04513.12 PFH34556.1 - 0.052 13.6 12.5 0.026 14.6 3.9 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 PFH34556.1 - 0.29 9.6 4.7 0.49 8.9 4.7 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4810 PF16068.5 PFH34556.1 - 0.83 10.2 4.0 73 4.0 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) DUF3037 PF11236.8 PFH34556.1 - 1.5 9.3 7.2 0.68 10.4 1.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) RRP36 PF06102.12 PFH34556.1 - 2.6 8.0 15.1 2.4 8.1 2.9 2.5 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 DUF4407 PF14362.6 PFH34556.1 - 3.3 7.0 27.5 3.6 6.8 9.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 PFH34556.1 - 6 5.6 7.0 9.4 5.0 7.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein BRE1 PF08647.11 PFH34556.1 - 9 6.4 31.9 0.27 11.3 9.8 4.1 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase zf-UBR PF02207.20 PFH34557.1 - 3.9e-15 55.8 16.5 8.9e-15 54.6 16.5 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) DUF726 PF05277.12 PFH34559.1 - 8.9e-112 373.4 0.4 8.9e-112 373.4 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF726) LCAT PF02450.15 PFH34559.1 - 0.052 12.7 0.0 0.081 12.1 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 PFH34559.1 - 0.058 13.0 0.1 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold SR-25 PF10500.9 PFH34561.1 - 0.0014 18.3 46.1 0.0027 17.4 45.8 1.6 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.12 PFH34561.1 - 0.18 11.6 20.1 0.23 11.3 20.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 PFH34561.1 - 0.4 10.9 14.6 0.53 10.5 14.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CCDC106 PF15794.5 PFH34561.1 - 0.95 9.1 30.7 1.3 8.7 30.4 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF572 PF04502.13 PFH34561.1 - 1.6 8.3 25.3 1.8 8.1 25.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF913 PF06025.12 PFH34561.1 - 1.6 7.6 7.3 1.8 7.5 7.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) HGTP_anticodon2 PF12745.7 PFH34561.1 - 2.3 7.6 18.3 3.9 6.9 18.3 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs MID_MedPIWI PF18296.1 PFH34561.1 - 2.5 7.8 10.4 3.2 7.5 10.4 1.1 1 0 0 1 1 1 0 MID domain of medPIWI Neur_chan_memb PF02932.16 PFH34561.1 - 3.1 7.8 10.2 4.2 7.4 10.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 PFH34561.1 - 3.2 6.3 12.9 3.7 6.1 12.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FUSC PF04632.12 PFH34561.1 - 5.8 5.3 4.2 6.7 5.1 4.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family IMUP PF15761.5 PFH34561.1 - 6.3 7.5 36.2 4.7 8.0 34.3 1.7 1 1 0 1 1 1 0 Immortalisation up-regulated protein DUF5427 PF10310.9 PFH34561.1 - 6.4 5.6 22.7 7.5 5.4 22.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CLP_protease PF00574.23 PFH34562.1 - 8.4e-45 152.9 0.0 2.1e-41 141.8 0.0 2.1 2 0 0 2 2 2 2 Clp protease Rad17 PF03215.15 PFH34563.1 - 0.019 14.9 0.0 0.48 10.3 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_assoc_2 PF16193.5 PFH34563.1 - 0.034 14.5 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain YqjK PF13997.6 PFH34565.1 - 0.12 12.6 0.4 0.45 10.8 0.4 2.0 1 0 0 1 1 1 0 YqjK-like protein DEAD PF00270.29 PFH34567.1 - 4.4e-36 124.3 0.0 7.1e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH34567.1 - 9.2e-16 58.2 0.0 3.9e-13 49.7 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain LRR_6 PF13516.6 PFH34568.1 - 2.6e-07 30.1 3.2 0.016 15.3 0.1 5.0 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 PFH34568.1 - 0.0006 20.1 10.9 0.47 10.9 0.4 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PFH34568.1 - 0.16 12.6 10.7 5.9 7.8 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat Ank_4 PF13637.6 PFH34569.1 - 3.5e-16 59.3 7.4 0.00036 21.0 0.1 6.1 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PFH34569.1 - 3.8e-16 59.4 7.1 6.6e-05 23.4 0.1 6.1 6 0 0 6 6 6 3 Ankyrin repeats (3 copies) Ank PF00023.30 PFH34569.1 - 2.9e-13 49.6 11.3 4.2e-05 23.8 0.4 6.7 7 0 0 7 7 7 3 Ankyrin repeat LRR_8 PF13855.6 PFH34569.1 - 2.7e-11 43.1 11.7 8.6e-10 38.2 1.6 4.1 3 1 0 4 4 4 2 Leucine rich repeat Ank_5 PF13857.6 PFH34569.1 - 2.2e-09 37.4 7.0 0.014 15.7 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH34569.1 - 3.5e-07 30.0 14.7 0.00076 19.8 0.1 8.1 9 0 0 9 9 9 1 Ankyrin repeat LRR_4 PF12799.7 PFH34569.1 - 1.5 9.3 15.4 0.44 11.0 1.2 3.8 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) Rep_fac-A_C PF08646.10 PFH34570.1 - 5.8e-30 104.0 0.5 1.8e-29 102.4 0.2 1.9 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 PFH34570.1 - 2e-23 82.2 0.8 1.9e-18 66.2 0.0 2.4 2 0 0 2 2 2 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 PFH34570.1 - 1.1e-08 35.0 1.3 5.6e-07 29.4 0.1 3.0 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 PFH34570.1 - 8.2e-05 22.4 0.3 0.00087 19.1 0.1 2.4 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DZR PF12773.7 PFH34570.1 - 0.064 13.3 1.5 0.099 12.7 0.6 1.7 2 0 0 2 2 2 0 Double zinc ribbon DUF4503 PF14951.6 PFH34570.1 - 0.073 11.5 0.1 0.12 10.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) JAMP PF05571.12 PFH34570.1 - 0.094 12.3 0.4 0.14 11.7 0.4 1.1 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein DHC_N1 PF08385.12 PFH34573.1 - 1.7e-153 512.3 11.4 1.7e-153 512.3 11.4 2.3 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 PFH34573.1 - 4.1e-150 499.3 4.3 7.4e-149 495.1 0.0 4.2 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 PFH34573.1 - 3.4e-94 315.0 0.0 8.6e-94 313.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DHC_N2 PF08393.13 PFH34573.1 - 8e-91 305.1 13.1 9.6e-85 285.1 0.2 4.4 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PFH34573.1 - 5.6e-87 291.8 0.4 4.4e-86 288.9 0.1 2.6 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PFH34573.1 - 2.5e-75 252.4 1.9 7.4e-75 250.9 1.9 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 PFH34573.1 - 5.2e-69 231.4 0.1 1.2e-65 220.4 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 PFH34573.1 - 5.7e-65 219.6 15.8 1.1e-64 218.6 15.8 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 PFH34573.1 - 1.1e-46 158.6 0.0 3.2e-46 157.2 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PFH34573.1 - 1.4e-39 134.9 0.0 1.1e-38 132.0 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 PFH34573.1 - 3e-28 98.6 0.0 4.1e-10 39.8 0.0 5.7 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 PFH34573.1 - 9e-26 90.5 1.2 4.6e-25 88.2 1.2 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 PFH34573.1 - 2.7e-20 72.4 0.0 1.9e-19 69.7 0.0 2.6 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 PFH34573.1 - 4.5e-08 33.6 0.0 0.18 12.2 0.0 5.9 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PFH34573.1 - 1.5e-07 32.0 2.3 0.86 10.0 0.0 6.4 6 0 0 6 6 5 2 AAA ATPase domain AAA_18 PF13238.6 PFH34573.1 - 2.2e-06 28.2 0.0 0.39 11.3 0.0 5.5 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 PFH34573.1 - 2.3e-06 27.9 0.1 0.0067 16.7 0.0 4.7 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 PFH34573.1 - 1e-05 25.7 0.0 0.2 11.8 0.0 5.0 4 0 0 4 4 4 1 AAA domain Rad17 PF03215.15 PFH34573.1 - 5.2e-05 23.3 0.7 0.044 13.7 0.1 4.1 4 0 0 4 4 3 1 Rad17 P-loop domain Mg_chelatase PF01078.21 PFH34573.1 - 0.00026 20.4 0.3 0.23 10.8 0.0 4.6 5 1 0 5 5 5 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 PFH34573.1 - 0.0056 17.1 0.0 52 4.3 0.0 4.3 4 0 0 4 4 4 0 RNA helicase AAA_30 PF13604.6 PFH34573.1 - 0.0079 15.9 0.3 19 4.9 0.0 3.9 3 0 0 3 3 3 0 AAA domain DUF3467 PF11950.8 PFH34573.1 - 0.014 15.6 0.0 0.052 13.8 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) T2SSE PF00437.20 PFH34573.1 - 0.021 13.9 0.1 0.13 11.3 0.1 2.4 3 0 0 3 3 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 PFH34573.1 - 0.035 14.4 2.9 6.7 7.0 0.0 4.3 4 0 0 4 4 3 0 AAA domain TsaE PF02367.17 PFH34573.1 - 0.035 14.1 0.5 0.55 10.2 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 PFH34573.1 - 0.13 12.1 0.1 14 5.5 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain HR1 PF02185.16 PFH34573.1 - 1.5 9.0 8.9 0.89 9.7 0.5 4.0 3 0 0 3 3 3 0 Hr1 repeat AAA_28 PF13521.6 PFH34573.1 - 1.9 8.7 4.8 61 3.8 0.0 4.4 5 0 0 5 5 3 0 AAA domain SIP1 PF04938.12 PFH34574.1 - 1.5e-21 77.1 1.5 1.5e-16 60.8 0.5 3.1 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF5318 PF17249.2 PFH34574.1 - 0.016 15.0 0.1 0.041 13.7 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5318) Citrate_synt PF00285.21 PFH34575.1 - 2.4e-123 411.8 0.0 3e-123 411.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain zf-CCHC_3 PF13917.6 PFH34576.1 - 0.0032 17.4 0.3 0.0082 16.1 0.1 1.7 2 0 0 2 2 2 1 Zinc knuckle DUF3641 PF12345.8 PFH34576.1 - 0.16 12.0 0.4 0.26 11.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3641) RRM_1 PF00076.22 PFH34577.1 - 1.5e-18 66.4 0.2 2.4e-18 65.7 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoU_methylase PF00588.19 PFH34579.1 - 3.5e-07 30.5 0.0 6.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family Bax1-I PF01027.20 PFH34581.1 - 1.1e-36 126.6 31.1 1.3e-36 126.4 31.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 MerC PF03203.14 PFH34581.1 - 2.8 8.4 16.8 1.2e+02 3.2 16.7 2.6 1 1 0 1 1 1 0 MerC mercury resistance protein MMR_HSR1 PF01926.23 PFH34583.1 - 3.3e-41 139.9 0.0 8.7e-20 70.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 PFH34583.1 - 2.1e-25 88.8 0.1 4.7e-25 87.7 0.1 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 PFH34583.1 - 3.4e-18 65.7 0.3 6.1e-09 35.6 0.1 4.9 3 2 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 PFH34583.1 - 3.3e-12 46.4 0.1 4.7e-05 23.0 0.0 5.5 3 3 0 3 3 3 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PFH34583.1 - 3.6e-09 36.8 0.0 0.098 12.6 0.0 4.2 4 0 0 4 4 4 2 RsgA GTPase Roc PF08477.13 PFH34583.1 - 2.9e-08 34.0 0.0 0.0019 18.4 0.0 3.6 3 1 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 PFH34583.1 - 9.1e-07 29.1 5.9 0.0051 16.9 0.0 4.4 4 1 0 5 5 4 1 Dynamin family AIG1 PF04548.16 PFH34583.1 - 1.2e-06 28.0 0.0 0.0026 17.1 0.0 2.4 2 0 0 2 2 2 2 AIG1 family Ras PF00071.22 PFH34583.1 - 1.7e-05 24.4 0.0 0.46 10.1 0.0 3.4 3 1 0 3 3 3 2 Ras family AAA_22 PF13401.6 PFH34583.1 - 0.00036 20.8 0.0 0.87 9.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain MMR_HSR1_Xtn PF16897.5 PFH34583.1 - 0.00076 19.5 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 2 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 PFH34583.1 - 0.00086 19.8 0.0 0.33 11.5 0.0 2.9 3 0 0 3 3 3 1 ABC transporter TniB PF05621.11 PFH34583.1 - 0.0034 16.8 0.0 4.5 6.6 0.0 3.0 2 1 0 2 2 2 2 Bacterial TniB protein IstB_IS21 PF01695.17 PFH34583.1 - 0.0035 17.1 0.0 0.57 9.9 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein SRPRB PF09439.10 PFH34583.1 - 0.0044 16.5 0.0 0.64 9.4 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PFH34583.1 - 0.0056 16.1 0.0 0.15 11.4 0.0 2.4 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Septin PF00735.18 PFH34583.1 - 0.006 15.9 0.0 1 8.5 0.0 2.4 2 0 0 2 2 2 1 Septin RNA_helicase PF00910.22 PFH34583.1 - 0.0091 16.4 0.0 6.8 7.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 PFH34583.1 - 0.011 16.0 0.0 0.56 10.4 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PFH34583.1 - 0.014 15.1 0.0 0.69 9.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 PFH34583.1 - 0.017 14.8 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PFH34583.1 - 0.027 14.9 2.1 3 8.2 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain MeaB PF03308.16 PFH34583.1 - 0.028 13.4 0.0 6.3 5.7 0.0 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 PFH34583.1 - 0.039 14.5 0.0 3.6 8.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PFH34583.1 - 0.06 13.8 0.0 3.1 8.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 PFH34583.1 - 0.078 12.3 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 PFH34583.1 - 0.12 12.3 0.1 6 6.8 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_15 PF13175.6 PFH34583.1 - 0.31 10.7 0.0 10 5.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.25 PFH34585.1 - 8.7e-59 199.0 0.0 1.5e-58 198.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34585.1 - 8.7e-35 120.2 0.0 1.5e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PFH34585.1 - 0.0082 15.0 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase NUC173 PF08161.12 PFH34586.1 - 4.6e-18 65.6 1.5 1.3e-17 64.2 0.5 2.4 2 0 0 2 2 2 1 NUC173 domain RTP1_C1 PF10363.9 PFH34586.1 - 0.0001 22.5 3.5 0.00032 20.9 0.4 3.3 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 PFH34586.1 - 0.12 12.7 3.0 0.71 10.3 0.5 3.8 2 0 0 2 2 2 0 HEAT repeat CDC45 PF02724.14 PFH34586.1 - 0.63 8.3 18.4 1.6 7.0 18.4 1.6 1 0 0 1 1 1 0 CDC45-like protein CENP-Q PF13094.6 PFH34588.1 - 6.8 6.9 44.6 0.12 12.6 16.1 3.7 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit WDCP PF15390.6 PFH34588.1 - 8.9 4.5 14.5 18 3.5 14.5 1.5 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family GCV_H PF01597.19 PFH34589.1 - 7.4e-20 71.1 0.1 1.5e-15 57.2 0.0 3.1 3 1 0 3 3 3 2 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 PFH34589.1 - 0.0007 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Amelin PF05111.12 PFH34590.1 - 0.057 12.6 0.2 0.12 11.5 0.2 1.4 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) Methyltransf_PK PF05891.12 PFH34592.1 - 0.19 11.2 0.3 0.34 10.4 0.0 1.5 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Chorismate_bind PF00425.18 PFH34593.1 - 2.5e-88 296.0 0.0 3.7e-88 295.4 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 PFH34593.1 - 1.4e-35 122.8 0.0 2.2e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 PFH34593.1 - 5.2e-07 29.6 0.1 1.4e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 Anth_synt_I_N PF04715.13 PFH34593.1 - 2.9e-06 27.5 0.0 1e-05 25.8 0.0 2.1 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region BTB_2 PF02214.22 PFH34594.1 - 1e-07 32.2 0.1 6.5e-07 29.6 0.1 2.2 1 1 0 1 1 1 1 BTB/POZ domain ELM2 PF01448.24 PFH34595.1 - 0.0035 18.1 0.0 0.0072 17.1 0.0 1.5 1 0 0 1 1 1 1 ELM2 domain Mito_carr PF00153.27 PFH34596.1 - 4.7e-48 161.1 2.8 1.5e-15 56.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein SAP PF02037.27 PFH34597.1 - 3.9e-15 55.2 0.3 1.5e-14 53.3 0.3 2.1 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 PFH34597.1 - 0.00012 21.8 25.7 0.07 12.9 2.1 4.1 2 2 2 4 4 4 4 Tho1/MOS11 C-terminal domain DNAPolymera_Pol PF11590.8 PFH34597.1 - 0.7 9.8 8.2 0.34 10.8 0.7 3.4 2 1 1 3 3 3 0 DNA polymerase catalytic subunit Pol Diphthami_syn_2 PF01902.17 PFH34598.1 - 1.4e-29 103.2 0.0 2.6e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Diphthamide synthase RINGv PF12906.7 PFH34599.1 - 7.4e-13 48.4 6.0 1.3e-12 47.7 6.0 1.4 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.26 PFH34599.1 - 1.1e-12 48.1 0.2 9.6e-10 38.7 0.1 2.6 2 0 0 2 2 2 2 FHA domain Yop-YscD_cpl PF16697.5 PFH34599.1 - 1.3e-05 25.4 0.1 0.0009 19.5 0.0 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FANCL_C PF11793.8 PFH34599.1 - 0.03 14.5 3.3 0.053 13.7 3.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 PFH34599.1 - 0.24 11.8 5.6 0.44 10.9 5.6 1.5 1 0 0 1 1 1 0 Ring finger domain C2 PF00168.30 PFH34600.1 - 8.7e-18 64.5 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 C2 domain UQ_con PF00179.26 PFH34601.1 - 4.3e-44 149.6 0.0 5.2e-44 149.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PFH34601.1 - 0.18 11.5 0.1 0.43 10.3 0.1 1.6 2 0 0 2 2 2 0 Prokaryotic E2 family B DnaJ PF00226.31 PFH34602.1 - 1.1e-05 25.4 0.1 1.7e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 PFH34602.1 - 1.7e-05 24.9 0.0 1.7e-05 24.9 0.0 2.1 1 1 1 2 2 2 1 Pam16 CtaG_Cox11 PF04442.14 PFH34603.1 - 4e-42 143.8 0.1 2.5e-34 118.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome c oxidase assembly protein CtaG/Cox11 Dus PF01207.17 PFH34606.1 - 1.9e-59 201.3 0.0 1.9e-48 165.2 0.0 3.1 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) ThiG PF05690.14 PFH34606.1 - 0.0091 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 PFH34606.1 - 0.049 12.8 0.0 0.32 10.2 0.0 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Pkinase PF00069.25 PFH34607.1 - 7.8e-19 68.1 0.0 1.9e-18 66.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 PFH34607.1 - 8.2e-15 54.9 0.0 1.5e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH34607.1 - 0.00063 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH34607.1 - 0.025 14.5 0.1 0.065 13.1 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 PFH34607.1 - 0.25 10.7 0.0 0.45 9.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 PFH34608.1 - 2.6e-49 164.9 0.0 2.6e-19 68.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH34608.1 - 1.5e-05 25.0 0.0 0.076 13.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 PFH34608.1 - 0.004 17.1 0.0 0.023 14.7 0.0 2.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 PFH34608.1 - 0.01 15.4 0.0 0.89 9.2 0.0 3.1 3 1 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyoxalase_5 PF14696.6 PFH34608.1 - 0.027 14.6 0.1 8.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DbpA PF03880.15 PFH34608.1 - 0.2 11.7 0.0 39 4.3 0.0 3.1 3 0 0 3 3 3 0 DbpA RNA binding domain DUF3827 PF12877.7 PFH34609.1 - 0.076 11.4 4.2 0.11 10.9 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Sin_N PF04801.13 PFH34609.1 - 0.23 10.7 3.0 0.36 10.0 0.7 2.0 2 0 0 2 2 2 0 Sin-like protein conserved region SAPS PF04499.15 PFH34609.1 - 0.81 8.4 4.6 1.1 7.9 4.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nucleo_P87 PF07267.11 PFH34609.1 - 0.82 8.4 5.7 1.1 8.0 5.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 PFH34609.1 - 0.83 8.3 2.8 1.1 7.9 2.8 1.3 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 PFH34609.1 - 0.88 9.4 12.5 1.4 8.8 12.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 PFH34609.1 - 4.5 5.4 8.2 0.21 9.9 2.9 1.4 2 0 0 2 2 2 0 CDC45-like protein RNase_PH PF01138.21 PFH34610.1 - 6.5e-10 39.6 0.0 1.4e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PFH34610.1 - 0.00025 21.0 0.0 0.00054 19.9 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Apt1 PF10351.9 PFH34611.1 - 0.38 9.6 11.2 0.63 8.8 11.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 PFH34611.1 - 0.7 8.4 12.5 1.1 7.8 12.5 1.2 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 PFH34611.1 - 2.7 7.8 17.8 0.74 9.7 14.2 1.9 2 0 0 2 2 2 0 SPX domain RNB PF00773.19 PFH34613.1 - 1.7e-64 218.3 0.0 2.8e-49 168.2 0.0 2.6 2 1 0 2 2 2 2 RNB domain Mvb12 PF09452.10 PFH34613.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 Nckap1 PF09735.9 PFH34613.1 - 0.31 8.9 0.0 0.45 8.4 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated apoptosis protein AbiEi_4 PF13338.6 PFH34614.1 - 0.027 14.6 1.0 1 9.6 0.2 3.3 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin DUF2540 PF10802.8 PFH34614.1 - 0.24 11.5 0.0 0.5 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) RNA_POL_M_15KD PF02150.16 PFH34615.1 - 5.5e-13 48.5 8.4 1.4e-12 47.3 5.2 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 PFH34615.1 - 7.8e-05 22.4 0.2 7.8e-05 22.4 0.2 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) PHD PF00628.29 PFH34615.1 - 0.19 11.7 8.2 7.2 6.6 3.6 3.1 3 1 0 3 3 3 0 PHD-finger Zn_ribbon_recom PF13408.6 PFH34615.1 - 0.24 12.0 0.3 0.24 12.0 0.3 1.9 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-ACC PF17848.1 PFH34615.1 - 0.29 11.2 0.3 0.29 11.2 0.3 2.8 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain IBR PF01485.21 PFH34615.1 - 0.47 10.7 4.2 1.4 9.2 1.3 2.6 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain DpnI PF06044.12 PFH34615.1 - 0.58 9.8 4.3 0.49 10.0 2.5 1.7 1 1 1 2 2 2 0 Dam-replacing family zinc_ribbon_10 PF10058.9 PFH34615.1 - 1.3 8.8 6.9 0.83 9.4 1.0 2.5 2 1 1 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 PFH34615.1 - 2.9 8.0 5.5 0.32 11.1 0.9 1.8 2 0 0 2 2 2 0 Double zinc ribbon GFA PF04828.14 PFH34615.1 - 3.2 8.1 4.9 12 6.3 0.3 2.8 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Peptidase_M16_C PF05193.21 PFH34616.1 - 1e-34 120.2 0.0 2.2e-34 119.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PFH34616.1 - 2e-23 83.0 0.0 6.4e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Ephrin_rec_like PF07699.13 PFH34617.1 - 6.6e-06 25.8 20.5 3.1e-05 23.6 7.4 3.8 3 0 0 3 3 3 2 Putative ephrin-receptor like 7tm_1 PF00001.21 PFH34617.1 - 6.7e-05 22.3 2.6 0.00024 20.5 1.7 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF3634 PF12321.8 PFH34617.1 - 0.037 14.4 0.1 0.076 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3634) RELT PF12606.8 PFH34617.1 - 0.17 10.9 1.5 0.7 8.9 1.5 2.0 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 PseudoU_synth_2 PF00849.22 PFH34618.1 - 3e-17 63.2 0.0 6.1e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase Peptidase_M41 PF01434.18 PFH34619.1 - 2.2e-55 187.5 0.0 3.7e-55 186.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PFH34619.1 - 3.6e-41 140.7 0.0 8.1e-41 139.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PFH34619.1 - 1.2e-13 50.7 0.2 2.7e-13 49.5 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PFH34619.1 - 3.8e-05 24.0 0.2 0.14 12.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 PFH34619.1 - 0.00041 20.4 0.0 0.0013 18.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 PFH34619.1 - 0.00047 19.5 0.0 0.00084 18.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 PFH34619.1 - 0.0038 17.0 0.0 0.0095 15.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 PFH34619.1 - 0.0061 17.0 0.1 0.021 15.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain DUF5327 PF17261.2 PFH34619.1 - 0.019 15.7 1.1 0.063 14.0 1.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5327) AAA_2 PF07724.14 PFH34619.1 - 0.025 14.7 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 PFH34619.1 - 0.046 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 PFH34619.1 - 0.059 12.7 0.2 0.14 11.5 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 PFH34619.1 - 0.064 13.4 0.1 0.2 11.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PFH34619.1 - 0.18 12.0 0.4 0.45 10.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 PFH34619.1 - 0.21 12.0 7.4 0.085 13.2 1.9 3.3 2 2 1 3 3 3 0 AAA ATPase domain ATP-synt_E PF05680.12 PFH34620.1 - 0.13 12.6 0.3 0.33 11.3 0.1 1.7 2 0 0 2 2 2 0 ATP synthase E chain Leu_Phe_trans PF03588.14 PFH34621.1 - 1.3e-19 70.3 0.4 7.7e-10 38.5 0.0 2.7 3 0 0 3 3 3 2 Leucyl/phenylalanyl-tRNA protein transferase AAA_2 PF07724.14 PFH34622.1 - 6.1e-41 140.4 0.1 4.2e-38 131.1 0.0 3.1 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 PFH34622.1 - 4.8e-24 84.3 1.0 1.2e-23 83.0 1.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 PFH34622.1 - 2.8e-21 76.3 0.0 2.8e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 PFH34622.1 - 2.9e-16 59.3 0.3 1.1e-15 57.4 0.0 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 PFH34622.1 - 5.6e-16 58.8 0.1 2.5e-10 40.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PFH34622.1 - 4.3e-14 53.2 6.2 1.4e-08 35.4 0.0 4.9 3 2 2 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 PFH34622.1 - 3.9e-11 42.9 0.3 4e-07 29.9 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 PFH34622.1 - 5.4e-11 42.9 0.5 0.0003 21.1 0.0 4.6 3 1 1 4 4 4 2 AAA domain AAA_7 PF12775.7 PFH34622.1 - 7.7e-08 32.1 0.0 0.0018 17.8 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 PFH34622.1 - 1.7e-06 27.5 0.0 0.099 12.0 0.0 3.7 4 0 0 4 4 4 2 Bacterial TniB protein RuvB_N PF05496.12 PFH34622.1 - 4.4e-06 26.5 0.1 0.7 9.6 0.0 4.0 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 PFH34622.1 - 1e-05 25.4 0.2 0.17 11.6 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 PFH34622.1 - 1.3e-05 25.2 0.0 0.3 11.1 0.0 3.2 4 0 0 4 4 3 2 AAA domain NACHT PF05729.12 PFH34622.1 - 3.6e-05 23.8 0.0 0.04 13.8 0.0 3.4 2 1 0 2 2 2 1 NACHT domain TsaE PF02367.17 PFH34622.1 - 9.5e-05 22.4 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 PFH34622.1 - 0.00012 22.0 0.1 0.21 11.4 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 PFH34622.1 - 0.00016 20.9 0.1 0.34 10.0 0.0 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF815) AAA_18 PF13238.6 PFH34622.1 - 0.00017 22.1 0.0 0.33 11.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain Roc PF08477.13 PFH34622.1 - 0.00022 21.4 0.0 0.65 10.2 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TIP49 PF06068.13 PFH34622.1 - 0.0004 19.7 0.2 0.085 12.0 0.0 3.3 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_30 PF13604.6 PFH34622.1 - 0.00045 20.0 2.0 0.66 9.7 0.0 4.1 3 1 1 4 4 4 1 AAA domain AAA_25 PF13481.6 PFH34622.1 - 0.00082 19.0 1.0 0.25 10.9 0.0 3.8 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 PFH34622.1 - 0.00086 19.7 0.0 3 8.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase RsgA_GTPase PF03193.16 PFH34622.1 - 0.0013 18.7 0.0 2.6 7.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ATPase_2 PF01637.18 PFH34622.1 - 0.0021 18.0 0.0 0.1 12.5 0.0 3.1 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea Clp_N PF02861.20 PFH34622.1 - 0.0023 18.0 0.0 0.16 12.1 0.0 3.1 2 0 0 2 2 2 1 Clp amino terminal domain, pathogenicity island component Mg_chelatase PF01078.21 PFH34622.1 - 0.0026 17.2 1.6 3.4 7.0 0.4 3.5 2 2 1 3 3 3 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 PFH34622.1 - 0.0053 16.1 0.0 1.5 8.1 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin ResIII PF04851.15 PFH34622.1 - 0.0078 16.2 0.0 0.92 9.5 0.0 3.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 PFH34622.1 - 0.012 15.3 0.0 6.9 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PFH34622.1 - 0.019 14.7 0.4 8.6 6.2 0.0 3.1 3 0 0 3 3 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PFH34622.1 - 0.025 15.1 0.0 1.3 9.6 0.0 2.7 2 0 0 2 2 2 0 ABC transporter MCM PF00493.23 PFH34622.1 - 0.032 13.3 0.0 1.6 7.7 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain AAA_23 PF13476.6 PFH34622.1 - 0.035 14.6 0.0 0.19 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 PFH34622.1 - 0.038 14.3 3.9 0.39 11.1 0.1 3.7 3 2 0 3 3 3 0 AAA domain DUF87 PF01935.17 PFH34622.1 - 0.074 13.1 0.1 2.4 8.2 0.0 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_28 PF13521.6 PFH34622.1 - 0.081 13.2 0.1 30 4.8 0.0 3.2 3 0 0 3 3 2 0 AAA domain Bac_DnaA PF00308.18 PFH34622.1 - 0.083 12.7 0.0 8.6 6.1 0.0 3.5 4 0 0 4 4 4 0 Bacterial dnaA protein Ribophorin_I PF04597.14 PFH34624.1 - 2e-105 353.6 0.0 2.4e-105 353.3 0.0 1.1 1 0 0 1 1 1 1 Ribophorin I DUF1754 PF08555.10 PFH34625.1 - 6.1e-09 36.6 24.2 4.2e-08 33.9 24.2 2.0 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) UBA2_C PF16195.5 PFH34625.1 - 0.00059 20.5 3.7 0.00059 20.5 3.7 2.1 1 1 1 2 2 2 1 SUMO-activating enzyme subunit 2 C-terminus BASP1 PF05466.12 PFH34625.1 - 0.51 10.3 19.7 0.57 10.2 19.7 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) NPR3 PF03666.13 PFH34625.1 - 1.7 7.4 12.2 1.9 7.2 12.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIIAH PF12685.7 PFH34625.1 - 2.3 8.0 12.7 2.8 7.7 12.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Red1 PF07964.11 PFH34625.1 - 5.5 5.1 15.9 6.5 4.9 15.9 1.0 1 0 0 1 1 1 0 Rec10 / Red1 FAM60A PF15396.6 PFH34625.1 - 5.7 6.9 11.4 7.7 6.5 11.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Nop53 PF07767.11 PFH34625.1 - 7.2 5.9 33.4 9.3 5.5 33.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Menin PF05053.13 PFH34625.1 - 8.6 4.6 9.6 9.2 4.5 9.6 1.0 1 0 0 1 1 1 0 Menin NIF PF03031.18 PFH34626.1 - 4.2e-22 78.6 0.0 5e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PDEase_I PF00233.19 PFH34627.1 - 1.9e-66 224.2 0.4 3.2e-66 223.4 0.4 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 PFH34627.1 - 0.006 16.8 0.1 0.015 15.6 0.1 1.6 1 0 0 1 1 1 1 HD domain G-gamma PF00631.22 PFH34627.1 - 0.034 14.1 0.2 0.089 12.8 0.2 1.6 1 0 0 1 1 1 0 GGL domain tRNA-synt_2 PF00152.20 PFH34629.1 - 7.5e-79 265.0 0.1 1e-78 264.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PFH34629.1 - 2.2e-06 27.6 0.2 4.3e-06 26.6 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PFH34629.1 - 0.00056 19.5 0.2 0.2 11.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-C3HC4_5 PF17121.5 PFH34629.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRP14 PF15459.6 PFH34629.1 - 1.1 9.9 4.4 2.2 9.0 4.4 1.4 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Phage_holin_7_1 PF16081.5 PFH34629.1 - 2.4 8.4 7.4 1.3 9.2 0.1 2.2 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF3273 PF11677.8 PFH34632.1 - 1.9e-103 345.4 8.4 2.2e-103 345.2 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF3273 PF11677.8 PFH34633.1 - 1.3e-103 346.0 8.4 1.4e-103 345.8 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) PHD PF00628.29 PFH34634.1 - 7.7e-07 28.9 2.1 7.7e-07 28.9 2.1 1.8 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 PFH34634.1 - 0.65 9.6 2.1 1.5 8.5 2.1 1.6 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 PFH34634.1 - 1.4 9.1 3.1 4.1 7.6 3.1 1.8 1 0 0 1 1 1 0 PHD-finger Peptidase_C53 PF05550.11 PFH34635.1 - 0.033 13.9 0.1 0.52 10.0 0.0 2.2 2 0 0 2 2 2 0 Pestivirus Npro endopeptidase C53 SBDS PF01172.18 PFH34636.1 - 4.3e-29 100.4 0.2 9.9e-29 99.3 0.2 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 PFH34636.1 - 7e-23 80.9 0.0 1.3e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain zf-C2H2_jaz PF12171.8 PFH34636.1 - 0.033 14.5 0.9 0.063 13.6 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AP3D1 PF06375.11 PFH34636.1 - 0.11 12.7 5.5 1.2 9.4 0.8 2.4 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DAGK_acc PF00609.19 PFH34637.1 - 1.2e-32 113.5 0.0 1.8e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 PFH34637.1 - 1.7e-14 53.5 0.1 2.1e-12 46.8 0.1 2.3 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain DUF2761 PF10959.8 PFH34637.1 - 0.022 14.8 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2761) NAD_kinase PF01513.21 PFH34637.1 - 0.17 11.1 0.1 0.27 10.4 0.1 1.3 1 0 0 1 1 1 0 ATP-NAD kinase DivIC PF04977.15 PFH34639.1 - 0.26 11.1 1.1 0.47 10.3 1.1 1.3 1 0 0 1 1 1 0 Septum formation initiator CRAL_TRIO PF00650.20 PFH34642.1 - 2.1e-22 79.5 0.0 3.5e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain cEGF PF12662.7 PFH34643.1 - 1.9e-53 177.9 83.3 1.5e-09 37.6 1.8 11.7 11 0 0 11 11 11 11 Complement Clr-like EGF-like EGF_CA PF07645.15 PFH34643.1 - 4.2e-50 167.7 135.9 4.9e-08 33.0 7.2 12.7 13 0 0 13 13 13 10 Calcium-binding EGF domain FXa_inhibition PF14670.6 PFH34643.1 - 4.9e-41 138.7 132.4 4.6e-11 42.8 6.5 11.2 11 0 0 11 11 11 9 Coagulation Factor Xa inhibitory site EGF PF00008.27 PFH34643.1 - 2.8e-16 59.5 130.2 0.00039 20.7 8.5 13.0 11 2 2 13 13 13 9 EGF-like domain EGF_3 PF12947.7 PFH34643.1 - 3.4e-15 56.0 107.0 0.00035 20.7 5.3 11.5 10 2 0 10 10 10 8 EGF domain hEGF PF12661.7 PFH34643.1 - 2.8e-07 30.9 108.4 0.00019 21.9 3.7 13.4 13 0 0 13 13 13 7 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 PFH34643.1 - 0.0091 16.3 8.2 0.023 15.0 1.3 10.5 9 2 1 10 10 10 4 Pvs28 EGF domain PrgH PF09480.10 PFH34644.1 - 0.0033 16.8 0.1 0.0049 16.2 0.1 1.2 1 0 0 1 1 1 1 Type III secretion system protein PrgH-EprH (PrgH) GDI PF00996.18 PFH34645.1 - 1.2e-214 712.7 0.0 1.4e-214 712.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 PFH34645.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Cpn60_TCP1 PF00118.24 PFH34646.1 - 4.8e-147 490.5 10.0 6.1e-147 490.2 10.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Apocytochr_F_C PF01333.19 PFH34646.1 - 0.014 15.4 0.2 0.04 14.0 0.2 1.8 1 0 0 1 1 1 0 Apocytochrome F, C-terminal ATP_bind_1 PF03029.17 PFH34647.1 - 1.3e-70 238.0 0.0 6.2e-64 216.1 0.0 2.0 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 PFH34647.1 - 0.00095 19.7 0.0 0.0049 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 PFH34647.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 PFH34647.1 - 0.013 15.9 0.1 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain CLP1_P PF16575.5 PFH34647.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 PFH34647.1 - 0.02 15.3 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 PFH34647.1 - 0.055 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 PFH34647.1 - 0.056 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 PFH34647.1 - 0.062 12.3 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein GTP_EFTU PF00009.27 PFH34647.1 - 0.063 12.8 0.0 1.2 8.7 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 PFH34647.1 - 0.074 13.3 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 PFH34647.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Cytidylate_kin PF02224.18 PFH34647.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_24 PF13479.6 PFH34647.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PFH34647.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-CCCH PF00642.24 PFH34648.1 - 3e-07 30.2 6.0 0.00013 21.8 0.5 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 PFH34648.1 - 0.0016 18.7 1.6 0.0045 17.2 1.6 1.8 1 0 0 1 1 1 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 PFH34648.1 - 0.045 13.8 10.3 0.022 14.8 1.6 3.8 3 1 0 3 3 3 0 Zinc finger domain Torus PF16131.5 PFH34648.1 - 0.65 10.7 6.2 0.23 12.2 0.3 2.8 2 1 1 3 3 3 0 Torus domain zf-CCCH_2 PF14608.6 PFH34648.1 - 5.5 7.6 11.6 3.1 8.4 1.8 3.1 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Mitofilin PF09731.9 PFH34649.1 - 5.4e-16 58.6 41.5 4.6e-09 35.7 34.5 3.2 2 1 0 2 2 2 2 Mitochondrial inner membrane protein TPR_10 PF13374.6 PFH34649.1 - 0.11 12.4 4.8 0.86 9.6 2.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PFH34649.1 - 1.7 9.0 4.1 23 5.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MmgE_PrpD PF03972.14 PFH34650.1 - 7.4e-59 199.4 1.7 2.4e-58 197.7 1.7 1.6 1 1 0 1 1 1 1 MmgE/PrpD family zf-rbx1 PF12678.7 PFH34651.1 - 4.5e-25 87.7 11.6 8.4e-25 86.8 11.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PFH34651.1 - 5.3e-17 61.7 9.3 7.2e-17 61.2 9.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 PFH34651.1 - 2.8e-06 27.5 14.8 0.00012 22.3 14.8 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PFH34651.1 - 3.3e-05 23.6 2.3 3.3e-05 23.6 2.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PFH34651.1 - 0.0013 18.5 11.2 0.016 15.0 11.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PFH34651.1 - 0.26 10.9 14.7 0.077 12.6 5.0 2.5 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 PFH34651.1 - 0.28 11.4 7.9 2.3 8.4 8.2 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 PFH34651.1 - 0.45 10.6 7.9 2.2 8.4 7.9 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 PFH34651.1 - 0.56 10.0 16.3 0.33 10.7 9.1 2.4 1 1 1 2 2 2 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 PFH34651.1 - 0.66 9.9 10.3 1.5 8.7 4.0 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH34651.1 - 3.1 7.8 10.2 11 6.1 10.2 2.0 1 1 0 1 1 1 0 zinc-RING finger domain DUF1759 PF03564.15 PFH34652.1 - 0.024 14.6 0.0 0.024 14.6 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1759) TFIIA PF03153.13 PFH34652.1 - 9.8 6.1 17.6 25 4.7 17.6 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 PFH34653.1 - 2.1e-13 50.5 9.7 5.5e-05 23.8 0.8 7.1 7 1 0 7 7 7 3 WD domain, G-beta repeat LANC_like PF05147.13 PFH34655.1 - 1.3e-62 211.4 0.0 1.6e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Methyltransf_11 PF08241.12 PFH34656.1 - 2.7e-12 47.2 0.0 1.5e-07 32.0 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 PFH34656.1 - 8.2e-12 45.7 0.1 5.6e-06 27.0 0.1 3.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 PFH34656.1 - 2.7e-11 43.5 0.0 2.1e-09 37.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH34656.1 - 8.9e-08 32.8 0.0 4.8e-05 24.0 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PFH34656.1 - 0.00021 21.2 0.0 0.54 10.1 0.0 3.3 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_24 PF13578.6 PFH34656.1 - 0.00033 21.6 0.0 0.01 16.9 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.17 PFH34656.1 - 0.00078 18.9 0.0 0.038 13.4 0.0 2.3 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Herpes_UL52 PF03121.15 PFH34657.1 - 5.8e-10 39.0 0.1 5.8e-10 39.0 0.1 1.8 2 0 0 2 2 2 1 Herpesviridae UL52/UL70 DNA primase RCS1 PF07326.11 PFH34658.1 - 0.083 12.8 1.1 6 6.7 0.2 2.4 2 0 0 2 2 2 0 Regulator of chromosome segregation 1 rRNA_proc-arch PF13234.6 PFH34659.1 - 4.5e-57 194.0 0.0 1.3e-56 192.6 0.0 1.8 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 PFH34659.1 - 1.2e-51 174.7 0.1 4.8e-51 172.7 0.1 2.2 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 PFH34659.1 - 4.6e-20 72.1 0.1 7.2e-18 65.0 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH34659.1 - 5.2e-07 30.0 0.0 4.4e-06 27.0 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Shisa PF13908.6 PFH34659.1 - 0.044 14.0 0.1 0.044 14.0 0.1 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Mob_synth_C PF06463.13 PFH34660.1 - 1.9e-28 98.9 0.4 9.8e-20 70.8 0.3 3.2 3 0 0 3 3 3 2 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 PFH34660.1 - 6.6e-24 85.2 0.0 1.6e-23 83.9 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily CRAL_TRIO PF00650.20 PFH34662.1 - 2.8e-18 66.1 0.0 4.6e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain ACBP PF00887.19 PFH34662.1 - 3.6e-05 23.9 0.1 0.00014 22.0 0.0 2.1 2 0 0 2 2 2 1 Acyl CoA binding protein EF-hand_1 PF00036.32 PFH34663.1 - 1.5e-25 86.8 7.9 2.6e-07 29.7 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PFH34663.1 - 3.5e-22 78.6 5.3 2.7e-12 47.0 0.7 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PFH34663.1 - 2.8e-20 70.8 6.4 1.6e-06 27.3 0.4 4.9 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 PFH34663.1 - 2.5e-19 67.5 6.8 0.00083 19.1 0.1 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PFH34663.1 - 4.3e-12 45.7 6.9 2.6e-05 24.0 1.8 4.0 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PFH34663.1 - 4.7e-09 36.6 0.2 0.00027 21.2 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PFH34663.1 - 7.1e-06 25.9 3.6 0.084 12.8 0.5 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 PFH34663.1 - 0.00034 20.9 0.1 0.095 13.0 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain Dockerin_1 PF00404.18 PFH34663.1 - 0.0032 17.6 3.3 0.075 13.2 0.1 3.5 2 1 2 4 4 4 3 Dockerin type I domain Caleosin PF05042.13 PFH34663.1 - 0.056 13.4 1.6 3.7 7.5 0.0 3.2 2 1 1 4 4 4 0 Caleosin related protein Fe-S_biosyn PF01521.20 PFH34664.1 - 1.2e-09 38.4 0.0 6.6e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis Amidohydro_2 PF04909.14 PFH34664.1 - 0.0069 16.2 2.6 0.0069 16.2 1.4 1.6 2 0 0 2 2 2 1 Amidohydrolase UFC1 PF08694.11 PFH34666.1 - 6.8e-80 266.1 0.1 7.7e-80 266.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 PFH34666.1 - 0.017 14.7 0.0 0.032 13.9 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme RWD PF05773.22 PFH34666.1 - 0.073 13.4 0.0 0.094 13.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain Epimerase_2 PF02350.19 PFH34666.1 - 0.17 10.7 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Choline_transpo PF04515.12 PFH34667.1 - 7.6e-54 183.1 35.1 1.2e-48 166.0 25.2 3.4 4 1 0 4 4 4 2 Plasma-membrane choline transporter Toxin_16 PF07945.11 PFH34667.1 - 3.7 7.5 16.8 3.2 7.7 0.6 3.2 2 0 0 2 2 2 0 Janus-atracotoxin MISS PF15822.5 PFH34668.1 - 0.13 12.0 0.0 7 6.4 0.0 2.0 1 1 1 2 2 2 0 MAPK-interacting and spindle-stabilising protein-like DUF4589 PF15252.6 PFH34669.1 - 0.014 15.4 0.3 0.026 14.5 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4589) ADIP PF11559.8 PFH34669.1 - 0.11 12.6 13.4 0.34 11.0 11.8 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 PFH34669.1 - 0.17 9.8 2.6 0.18 9.7 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 PFH34669.1 - 1.3 9.0 10.1 0.97 9.5 0.4 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JAKMIP_CC3 PF16034.5 PFH34669.1 - 1.5 8.7 10.1 2.9 7.8 10.1 1.5 1 0 0 1 1 1 0 JAKMIP CC3 domain Tho2 PF11262.8 PFH34669.1 - 1.7 7.8 7.9 1.5 7.9 4.8 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 HIP1_clath_bdg PF16515.5 PFH34669.1 - 1.7 9.3 10.7 0.23 12.1 3.3 2.9 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Filament PF00038.21 PFH34669.1 - 1.9 8.0 13.1 0.75 9.3 2.8 2.7 2 1 1 3 3 3 0 Intermediate filament protein TMPIT PF07851.13 PFH34669.1 - 2.8 7.1 5.4 4.6 6.4 5.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein UCH PF00443.29 PFH34670.1 - 5.7e-40 137.4 0.0 1.7e-39 135.9 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 PFH34670.1 - 1.7e-11 44.3 0.0 5.5e-11 42.6 0.0 2.0 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 PFH34670.1 - 1.1e-10 41.6 0.0 1.2e-08 34.9 0.0 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 PFH34670.1 - 3.3e-08 33.3 0.1 0.00029 20.7 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 PFH34670.1 - 4.1e-08 32.9 0.1 1e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 Variant UBP zinc finger SANT_DAMP1_like PF16282.5 PFH34672.1 - 1.6e-22 79.5 0.1 2.4e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 RCC1 PF00415.18 PFH34673.1 - 8.7e-39 131.9 15.4 3.6e-10 40.3 0.5 8.7 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH34673.1 - 1.4e-23 82.1 27.4 1.4e-05 24.7 1.0 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat zf-RanBP PF00641.18 PFH34673.1 - 1.3e-05 24.4 4.3 1.7e-05 24.0 2.5 2.1 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RNase_PH PF01138.21 PFH34676.1 - 8.2e-15 55.5 0.0 1.7e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PFH34676.1 - 0.036 14.1 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 CHCH PF06747.13 PFH34677.1 - 0.00015 21.8 7.4 0.00021 21.3 7.4 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 PFH34677.1 - 0.048 13.7 2.3 0.42 10.7 0.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 PFH34677.1 - 0.082 12.9 0.9 0.082 12.9 0.9 2.0 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF2076 PF09849.9 PFH34677.1 - 0.95 9.4 10.7 0.78 9.7 9.5 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Methyltr_RsmB-F PF01189.17 PFH34679.1 - 5.1e-30 104.6 0.0 3.7e-29 101.8 0.0 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 PFH34679.1 - 8e-07 28.6 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PFH34679.1 - 8.1e-06 25.7 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmF_N PF17125.5 PFH34679.1 - 3.2e-05 24.4 0.0 6.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF GCD14 PF08704.10 PFH34679.1 - 0.00022 21.0 0.0 0.00033 20.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.6 PFH34679.1 - 0.0013 19.4 0.0 0.0027 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PFH34679.1 - 0.0029 17.2 0.0 0.057 13.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 PFH34679.1 - 0.0034 17.2 0.0 0.0054 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 PFH34679.1 - 0.022 15.8 0.0 0.049 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Atg14 PF10186.9 PFH34680.1 - 7.8 5.5 10.1 8.6 5.3 8.3 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAA_hydro_N_2 PF18288.1 PFH34681.1 - 0.049 14.1 0.0 0.17 12.3 0.0 1.9 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 Sulfate_transp PF00916.20 PFH34684.1 - 8.4e-23 80.7 24.8 4.7e-13 48.7 13.4 2.2 2 0 0 2 2 2 2 Sulfate permease family Proteasome PF00227.26 PFH34686.1 - 1.2e-60 204.3 0.0 1.5e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PFH34686.1 - 0.021 14.5 0.3 0.021 14.5 0.3 2.0 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature TMEM234 PF10639.9 PFH34687.1 - 3.5e-26 91.5 0.3 8.4e-26 90.3 0.3 1.6 1 1 0 1 1 1 1 Putative transmembrane family 234 Colicin_im PF03857.13 PFH34687.1 - 0.049 13.6 0.2 0.094 12.7 0.0 1.6 2 0 0 2 2 2 0 Colicin immunity protein DNA_pol_phi PF04931.13 PFH34688.1 - 6e-23 80.9 55.1 5e-16 58.0 1.4 4.4 4 0 0 4 4 4 3 DNA polymerase phi SDA1 PF05285.12 PFH34688.1 - 0.0032 17.0 22.0 0.0032 17.0 22.0 4.4 4 0 0 4 4 4 1 SDA1 Zip PF02535.22 PFH34688.1 - 0.065 12.4 0.6 0.18 11.0 0.6 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter G_path_suppress PF15991.5 PFH34690.1 - 0.025 14.8 0.1 0.17 12.0 0.0 2.4 2 0 0 2 2 2 0 G-protein pathway suppressor CCDC50_N PF15295.6 PFH34690.1 - 0.21 11.7 0.1 0.21 11.7 0.1 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 50 N-terminus Kinesin PF00225.23 PFH34691.1 - 3.6e-82 276.0 0.0 4.9e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PFH34691.1 - 1.6e-13 50.9 0.0 2.5e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding AAA_6 PF12774.7 PFH34693.1 - 1.4e-120 402.2 0.0 3.5e-118 394.3 0.0 3.4 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PFH34693.1 - 2.3e-109 366.1 4.3 4.3e-109 365.2 0.0 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PFH34693.1 - 1.3e-94 316.9 0.0 1.2e-93 313.7 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PFH34693.1 - 5.1e-71 238.3 0.0 1.8e-68 230.0 0.3 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 PFH34693.1 - 3.8e-63 213.2 0.0 1.5e-44 152.3 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_7 PF12775.7 PFH34693.1 - 3e-55 186.5 0.0 1.1e-52 178.2 0.0 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 PFH34693.1 - 3.4e-46 157.9 6.0 1e-45 156.3 6.0 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 PFH34693.1 - 4e-46 156.8 0.0 7.8e-46 155.9 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PFH34693.1 - 1.4e-37 128.4 0.0 1.1e-36 125.5 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 PFH34693.1 - 3.4e-20 72.4 0.0 9.5e-06 25.7 0.0 5.9 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PFH34693.1 - 2.5e-12 46.9 0.0 7.8e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 PFH34693.1 - 8.9e-11 42.0 0.0 2e-09 37.6 0.0 2.9 2 1 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 PFH34693.1 - 7.5e-10 39.4 0.0 4.7e-05 23.8 0.0 4.0 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PFH34693.1 - 2.1e-07 31.3 0.1 0.0023 18.2 0.0 4.1 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 PFH34693.1 - 2e-06 28.4 0.3 0.018 15.6 0.0 4.2 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 PFH34693.1 - 6.3e-05 23.4 21.8 0.0044 17.4 0.0 7.0 6 0 0 6 6 5 2 AAA ATPase domain AAA_14 PF13173.6 PFH34693.1 - 0.0015 18.5 0.0 0.0065 16.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 PFH34693.1 - 0.0016 18.1 0.3 0.3 10.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PFH34693.1 - 0.0032 17.7 0.1 13 6.0 0.1 4.3 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 PFH34693.1 - 0.0041 17.3 0.3 0.019 15.2 0.1 2.3 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 PFH34693.1 - 0.0062 15.8 0.0 0.087 12.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 PFH34693.1 - 0.026 14.4 0.0 0.086 12.7 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 PFH34693.1 - 0.027 14.2 7.1 13 5.4 0.2 4.6 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 PFH34693.1 - 0.028 14.3 0.1 1.3 8.9 0.1 3.3 3 0 0 3 3 3 0 NTPase NACHT PF05729.12 PFH34693.1 - 0.03 14.3 0.1 0.34 10.8 0.0 2.8 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 PFH34693.1 - 0.037 13.9 0.0 0.37 10.7 0.0 2.6 3 0 0 3 3 2 0 RsgA GTPase DASH_Duo1 PF08651.10 PFH34693.1 - 0.041 13.7 3.4 0.47 10.2 0.1 4.3 4 0 0 4 4 4 0 DASH complex subunit Duo1 AAA_29 PF13555.6 PFH34693.1 - 0.049 13.4 2.6 14 5.5 0.0 3.8 4 0 0 4 4 3 0 P-loop containing region of AAA domain AAA_2 PF07724.14 PFH34693.1 - 0.074 13.2 0.0 4.3 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 PFH34693.1 - 0.086 12.6 0.0 23 4.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain T2SSE PF00437.20 PFH34693.1 - 0.087 11.9 0.1 0.28 10.2 0.0 1.9 2 0 0 2 2 1 0 Type II/IV secretion system protein Ras PF00071.22 PFH34693.1 - 0.1 12.2 0.2 0.82 9.3 0.1 2.6 3 0 0 3 3 3 0 Ras family RNA_helicase PF00910.22 PFH34693.1 - 0.15 12.5 0.0 48 4.4 0.0 3.4 3 0 0 3 3 3 0 RNA helicase DUF2075 PF09848.9 PFH34693.1 - 0.18 11.0 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 PFH34693.1 - 0.21 11.6 1.3 7.6 6.6 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 PFH34693.1 - 0.59 9.0 4.2 0.21 10.5 0.1 2.3 3 0 0 3 3 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 PFH34693.1 - 0.73 10.0 7.0 19 5.4 0.0 4.6 5 0 0 5 5 3 0 AAA domain SWIRM PF04433.17 PFH34694.1 - 2.7e-20 72.5 0.0 5e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 PFH34694.1 - 3.2e-12 46.2 15.3 1e-11 44.6 15.3 1.9 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 PFH34694.1 - 6.4e-12 45.5 0.1 1.5e-11 44.3 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PFH34694.1 - 2.1e-07 31.1 0.0 4.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4205 PF13898.6 PFH34696.1 - 2.9e-49 167.9 0.0 9.8e-35 120.1 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4205) UIM PF02809.20 PFH34696.1 - 0.007 16.2 10.7 0.53 10.3 1.7 3.0 2 0 0 2 2 2 2 Ubiquitin interaction motif Pinin_SDK_memA PF04696.13 PFH34697.1 - 2.1e-21 76.3 17.6 2.1e-21 76.3 17.6 2.5 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region NPAT_C PF15712.5 PFH34697.1 - 0.00099 17.9 1.7 0.0015 17.3 1.7 1.4 1 0 0 1 1 1 1 NPAT C terminus Cu_amine_oxid PF01179.20 PFH34698.1 - 2e-76 257.5 2.1 2e-76 257.5 2.1 1.8 2 0 0 2 2 2 1 Copper amine oxidase, enzyme domain MAM PF00629.23 PFH34698.1 - 8.6e-24 84.3 0.0 1.6e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Peptidase_U4 PF03419.13 PFH34700.1 - 1.7 7.9 6.6 1.8 7.8 6.6 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA GET2 PF08690.10 PFH34701.1 - 0.015 15.0 1.9 0.028 14.1 1.1 1.8 1 1 1 2 2 2 0 GET complex subunit GET2 zf-RING_9 PF13901.6 PFH34701.1 - 0.036 14.0 2.3 0.074 13.0 2.3 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Exonuc_VII_L PF02601.15 PFH34701.1 - 0.53 9.8 5.2 0.73 9.4 5.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Muted PF14942.6 PFH34701.1 - 0.55 10.6 6.7 0.9 9.9 6.7 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Sensor PF13796.6 PFH34701.1 - 0.88 9.6 2.3 4.1 7.4 0.3 2.5 1 1 1 2 2 2 0 Putative sensor CENP-H PF05837.12 PFH34701.1 - 1.6 9.2 9.8 0.84 10.1 5.1 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Baculo_PEP_C PF04513.12 PFH34701.1 - 7.3 6.6 5.8 21 5.1 1.2 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MA3 PF02847.17 PFH34702.1 - 1e-39 135.0 7.1 1e-13 51.2 0.0 3.2 3 0 0 3 3 3 3 MA3 domain EGF_3 PF12947.7 PFH34703.1 - 0.0019 18.4 11.3 0.0019 18.4 11.3 11.3 10 1 0 10 10 10 5 EGF domain EGF_MSP1_1 PF12946.7 PFH34703.1 - 0.0041 17.1 5.3 0.0041 17.1 5.3 9.2 8 1 0 8 8 8 2 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 PFH34703.1 - 0.023 15.0 96.6 0.058 13.7 4.8 10.6 10 1 0 10 10 10 0 Pvs28 EGF domain hEGF PF12661.7 PFH34703.1 - 5.1 7.9 95.9 0.13 13.0 0.8 12.6 13 1 0 13 13 13 0 Human growth factor-like EGF cEGF PF12662.7 PFH34703.1 - 10 6.2 84.5 0.075 13.0 2.1 10.2 11 0 0 11 11 11 0 Complement Clr-like EGF-like SRP19 PF01922.17 PFH34704.1 - 1.8e-24 86.5 0.0 2.3e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein HSP20 PF00011.21 PFH34705.1 - 1.3e-25 89.5 0.5 1.8e-25 89.1 0.5 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PFH34705.1 - 5e-10 38.8 0.0 7.6e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Transp_inhibit PF18791.1 PFH34705.1 - 0.081 12.4 1.4 0.16 11.5 1.4 1.4 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain zf-C2H2_4 PF13894.6 PFH34706.1 - 4.5e-06 27.1 2.2 0.1 13.5 0.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PFH34706.1 - 0.0002 21.6 3.0 0.002 18.4 1.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 PFH34706.1 - 0.00058 20.2 2.1 0.68 10.5 0.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type Rad50_zn_hook PF04423.14 PFH34706.1 - 0.016 15.1 0.7 0.48 10.3 0.8 2.3 1 1 1 2 2 2 0 Rad50 zinc hook motif LIM PF00412.22 PFH34706.1 - 0.062 13.5 1.9 0.11 12.7 1.9 1.4 1 0 0 1 1 1 0 LIM domain zf-Di19 PF05605.12 PFH34706.1 - 0.37 11.1 3.9 1.3 9.3 3.9 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Kin17_mid PF10357.9 PFH34707.1 - 2.7e-41 140.4 3.1 6.5e-41 139.2 3.0 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 PFH34707.1 - 4.1e-24 84.5 1.8 7.7e-24 83.6 1.8 1.5 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 PFH34707.1 - 0.026 14.9 3.6 0.054 13.9 3.6 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PFH34707.1 - 0.12 12.7 3.8 0.25 11.7 3.8 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Kinesin PF00225.23 PFH34710.1 - 2.8e-91 305.9 0.0 4.4e-91 305.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PFH34710.1 - 1.6e-16 60.5 0.0 3.2e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding MMR_HSR1 PF01926.23 PFH34711.1 - 1.9e-18 66.6 0.0 5.8e-18 65.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PFH34711.1 - 2.2e-06 27.7 0.0 0.045 13.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 PFH34711.1 - 2.2e-06 27.3 0.0 1.4e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PFH34711.1 - 2.9e-06 27.4 0.0 6.1e-05 23.1 0.1 2.2 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 PFH34711.1 - 3.8e-06 26.4 0.0 5.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 PFH34711.1 - 0.00042 19.9 0.0 4.4 6.8 0.0 3.3 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 PFH34711.1 - 0.008 15.9 0.0 2.4 7.9 0.0 2.6 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 PFH34711.1 - 0.024 15.2 0.0 0.044 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 PFH34711.1 - 0.14 12.4 0.0 0.81 9.9 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 PFH34711.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1_Xtn PF16897.5 PFH34711.1 - 0.23 11.5 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Redoxin PF08534.10 PFH34712.1 - 9.7e-28 96.7 0.0 1.6e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 PFH34712.1 - 5.8e-09 35.9 0.0 8.1e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family S1 PF00575.23 PFH34713.1 - 4.6e-21 74.9 0.1 4.8e-11 42.8 0.0 3.7 3 0 0 3 3 3 3 S1 RNA binding domain CENP-Q PF13094.6 PFH34713.1 - 3 8.0 14.5 0.66 10.2 5.1 2.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Ribosomal_S14 PF00253.21 PFH34714.1 - 3e-21 74.9 3.0 5.2e-21 74.2 3.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e HemX PF04375.14 PFH34716.1 - 0.27 10.5 10.5 0.45 9.7 10.5 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase TMEM247 PF15444.6 PFH34716.1 - 0.87 9.6 5.7 1.7 8.6 5.7 1.5 1 0 0 1 1 1 0 Transmembrane protein 247 Hydrolase_4 PF12146.8 PFH34717.1 - 2.1e-11 43.5 0.0 8.5e-10 38.3 0.0 3.0 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PFH34717.1 - 0.0055 17.3 3.7 0.0063 17.1 0.8 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family LSM PF01423.22 PFH34718.1 - 1e-18 66.7 0.0 1.2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 PFH34718.1 - 0.014 15.6 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain RNase_PH PF01138.21 PFH34719.1 - 1.8e-11 44.6 0.0 6e-11 43.0 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PFH34719.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 MFS_MOT1 PF16983.5 PFH34723.1 - 1.5 9.2 12.1 1.5 9.3 0.0 3.3 2 1 1 3 3 3 0 Molybdate transporter of MFS superfamily ABA_GPCR PF12430.8 PFH34724.1 - 2e-33 115.7 10.9 5.7e-33 114.2 10.9 1.7 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 PFH34724.1 - 2.3e-18 66.0 0.0 5.3e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Pkinase PF00069.25 PFH34725.1 - 9.7e-66 221.8 0.0 1.3e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34725.1 - 2.8e-36 125.2 0.0 3.9e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH34725.1 - 0.00017 21.0 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2252 PF10009.9 PFH34725.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Haspin_kinase PF12330.8 PFH34725.1 - 0.034 13.1 0.6 0.064 12.2 0.6 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 PFH34725.1 - 0.054 13.4 0.0 0.16 11.9 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 PFH34725.1 - 0.2 11.0 0.1 0.41 10.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 PFH34725.1 - 0.2 11.1 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TMEM51 PF15345.6 PFH34726.1 - 0.046 13.6 0.1 0.051 13.4 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 ATP19 PF11022.8 PFH34726.1 - 0.048 14.0 0.0 0.092 13.1 0.0 1.5 1 0 0 1 1 1 0 ATP synthase subunit K TUDOR PF00567.24 PFH34727.1 - 4.5e-07 29.9 1.7 1.6e-05 24.9 0.0 2.6 2 1 0 2 2 2 1 Tudor domain SMN PF06003.12 PFH34727.1 - 0.00067 19.0 0.1 0.00067 19.0 0.1 2.4 2 1 0 3 3 3 1 Survival motor neuron protein (SMN) SAWADEE PF16719.5 PFH34727.1 - 0.038 14.0 0.1 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 SAWADEE domain MCPsignal PF00015.21 PFH34727.1 - 0.19 11.6 5.1 0.62 9.9 5.1 1.9 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GvpK PF05121.12 PFH34727.1 - 0.69 10.0 7.7 0.91 9.6 2.4 2.5 1 1 1 2 2 2 0 Gas vesicle protein K V_ATPase_I PF01496.19 PFH34727.1 - 1.2 7.0 7.0 0.38 8.6 2.2 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FAM221 PF14753.6 PFH34728.1 - 1.5e-43 148.7 9.7 1.3e-29 103.2 7.7 2.1 1 1 1 2 2 2 2 Protein FAM221A/B GTP_EFTU PF00009.27 PFH34729.1 - 6.4e-54 182.5 0.0 1e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PFH34729.1 - 7.8e-41 138.9 0.2 1.9e-40 137.7 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PFH34729.1 - 1.7e-12 47.5 0.3 8.8e-12 45.2 0.3 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PFH34729.1 - 8.9e-05 22.6 0.0 0.0027 17.8 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FlpD PF02662.16 PFH34729.1 - 0.003 17.5 0.1 0.0093 16.0 0.0 1.8 2 0 0 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit Semialdhyde_dhC PF02774.18 PFH34729.1 - 0.085 12.9 0.3 0.29 11.2 0.1 2.0 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain FAST_1 PF06743.15 PFH34730.1 - 2.5e-05 24.1 0.1 10 6.1 0.1 5.1 5 0 0 5 5 5 4 FAST kinase-like protein, subdomain 1 TPR_1 PF00515.28 PFH34732.1 - 4.5e-08 32.6 11.0 0.00077 19.2 0.2 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PFH34732.1 - 1.4e-07 31.1 14.7 0.00074 19.5 0.3 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 PFH34732.1 - 2.3e-06 27.8 17.2 0.04 14.2 0.5 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 PFH34732.1 - 1.2e-05 25.0 17.1 0.17 11.8 1.4 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 PFH34732.1 - 4e-05 23.5 10.2 0.014 15.5 0.2 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 PFH34732.1 - 0.012 16.2 10.3 0.14 12.9 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 PFH34732.1 - 0.043 13.8 12.0 0.28 11.3 0.8 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 PFH34732.1 - 0.46 11.0 1.7 12 6.5 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 PFH34732.1 - 3.1 7.6 9.1 3.9 7.2 0.5 3.2 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 PFH34732.1 - 6.9 7.8 20.0 3.9 8.6 1.8 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat CPW_WPC PF09717.10 PFH34733.1 - 0.00077 20.4 30.9 0.094 13.7 0.0 8.5 4 4 2 6 6 6 2 Plasmodium falciparum domain of unknown function (CPW_WPC) SARS_X4 PF08779.10 PFH34733.1 - 0.54 10.5 6.7 4.1 7.7 0.1 4.3 3 1 2 5 5 5 0 SARS coronavirus X4 like FOG_N PF15888.5 PFH34733.1 - 0.74 10.2 30.4 8.7 6.8 0.1 9.5 4 3 6 11 11 11 0 Folded gastrulation N-terminus Antistasin PF02822.14 PFH34733.1 - 1.5 9.6 0.1 1.5 9.6 0.1 9.4 8 2 2 10 10 10 0 Antistasin family cEGF PF12662.7 PFH34733.1 - 2.9 7.9 33.7 9.3 6.3 0.0 9.6 11 0 0 11 11 11 0 Complement Clr-like EGF-like Kelch_4 PF13418.6 PFH34734.1 - 1.8e-46 155.9 8.8 1.7e-08 34.3 0.1 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 PFH34734.1 - 3.3e-46 154.6 0.0 8.8e-08 31.6 0.0 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 PFH34734.1 - 6.3e-44 146.4 1.1 2.7e-08 33.5 0.0 6.9 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 PFH34734.1 - 7.5e-42 140.7 0.0 8.3e-07 28.9 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 PFH34734.1 - 7.8e-37 124.9 29.9 7.8e-10 38.8 0.1 8.7 9 0 0 9 9 9 6 Galactose oxidase, central domain Kelch_6 PF13964.6 PFH34734.1 - 2.1e-33 113.5 1.8 4.5e-06 26.7 0.0 6.5 4 2 2 6 6 6 6 Kelch motif BTB PF00651.31 PFH34734.1 - 3.5e-21 75.5 0.2 6.7e-20 71.4 0.2 2.2 1 1 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PFH34734.1 - 0.13 12.4 0.1 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 BTB And C-terminal Kelch Epimerase PF01370.21 PFH34736.1 - 1.7e-40 139.0 0.0 3.9e-40 137.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PFH34736.1 - 5.9e-05 22.6 0.0 0.0094 15.4 0.0 2.7 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 PFH34736.1 - 0.00043 19.5 0.2 0.016 14.4 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Siva PF05458.12 PFH34736.1 - 0.019 14.6 4.8 0.032 13.9 4.8 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) RmlD_sub_bind PF04321.17 PFH34736.1 - 0.039 13.0 0.0 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain RAP1 PF07218.11 PFH34736.1 - 0.24 9.6 0.4 0.32 9.2 0.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 PFH34736.1 - 8.4 5.9 16.5 14 5.3 16.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC24 PF15669.5 PFH34736.1 - 9.6 6.0 5.6 16 5.3 5.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Metallophos PF00149.28 PFH34737.1 - 2.1e-37 129.6 0.1 3.1e-37 129.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PFH34737.1 - 0.027 14.9 0.5 0.058 13.8 0.5 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain NYD-SP12_N PF15015.6 PFH34737.1 - 0.13 10.7 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal YwqJ-deaminase PF14431.6 PFH34738.1 - 0.51 10.5 7.5 0.65 10.2 7.5 1.4 1 1 0 1 1 1 0 YwqJ-like deaminase DUF4554 PF15091.6 PFH34738.1 - 6.6 5.5 7.0 7.1 5.4 7.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) CDC45 PF02724.14 PFH34738.1 - 8.1 4.6 12.3 8.1 4.6 12.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 PFH34738.1 - 9.8 4.8 6.9 10 4.7 6.9 1.0 1 0 0 1 1 1 0 Presenilin tRNA-synt_1g PF09334.11 PFH34740.1 - 4.8e-32 111.2 0.0 2.8e-20 72.4 0.0 5.1 6 0 0 6 6 6 3 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PFH34740.1 - 1.2e-09 37.0 0.0 2.3e-07 29.5 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PFH34740.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA PAN_4 PF14295.6 PFH34742.1 - 1.1e-23 82.9 27.0 1.7e-07 31.0 3.1 4.7 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.26 PFH34742.1 - 2.9e-23 81.6 10.8 6.1e-06 26.1 0.0 4.3 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.12 PFH34742.1 - 0.00038 20.2 14.4 0.055 13.3 0.6 4.2 4 0 0 4 4 4 4 PAN-like domain MANEC PF07502.14 PFH34742.1 - 0.13 12.6 13.3 8.9 6.7 0.2 4.4 4 0 0 4 4 4 0 MANEC domain Sld5 PF05916.11 PFH34743.1 - 6.3e-08 33.0 0.4 1.1e-07 32.3 0.4 1.4 1 0 0 1 1 1 1 GINS complex protein Guanylate_cyc_2 PF09778.9 PFH34744.1 - 9.7e-24 83.9 0.1 1.5e-16 60.4 0.0 3.1 3 0 0 3 3 3 3 Guanylylate cyclase Peptidase_C39 PF03412.15 PFH34744.1 - 0.084 12.7 0.1 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Peptidase C39 family MSA-2c PF12238.8 PFH34744.1 - 0.43 10.5 2.0 0.97 9.4 2.0 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c Peptidase_S9_N PF02897.15 PFH34745.1 - 4.8e-115 384.7 0.5 6.4e-115 384.3 0.5 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 PFH34745.1 - 3.7e-65 219.4 0.0 8.2e-65 218.2 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 PFH34745.1 - 0.015 15.2 0.0 1.4 8.8 0.0 2.4 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 PFH34745.1 - 0.031 14.1 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 PFH34745.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase SUI1 PF01253.22 PFH34748.1 - 3e-26 91.8 0.5 3.8e-26 91.4 0.5 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.14 PFH34748.1 - 0.072 13.4 0.1 0.12 12.7 0.1 1.4 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) RNase_PH_C PF03725.15 PFH34748.1 - 0.16 12.0 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 GTP_EFTU PF00009.27 PFH34750.1 - 1.5e-42 145.3 0.0 2.1e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 PFH34750.1 - 2.1e-30 105.8 1.8 4.4e-30 104.8 1.8 1.6 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 PFH34750.1 - 1.2e-22 80.0 0.0 7.3e-22 77.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 PFH34750.1 - 1.2e-21 76.5 0.0 4.3e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PFH34750.1 - 3.5e-07 30.5 0.1 8.1e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 PFH34750.1 - 4.9e-06 26.5 0.0 1.4e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II Roc PF08477.13 PFH34750.1 - 0.00015 22.0 0.0 0.042 14.1 0.0 2.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 PFH34750.1 - 0.0002 21.4 0.0 0.00048 20.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 PFH34750.1 - 0.0062 16.0 0.0 2.6 7.5 0.0 3.1 3 0 0 3 3 3 1 ADP-ribosylation factor family Dynamin_N PF00350.23 PFH34750.1 - 0.042 13.9 0.0 4 7.5 0.0 2.3 1 1 1 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 PFH34750.1 - 0.057 13.3 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase SesA PF17107.5 PFH34750.1 - 0.068 13.4 0.1 0.18 12.0 0.1 1.7 2 0 0 2 2 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SRPRB PF09439.10 PFH34750.1 - 0.087 12.3 0.0 1.3 8.4 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Herpes_BTRF1 PF04682.12 PFH34750.1 - 0.12 11.7 0.0 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 Herpesvirus BTRF1 protein conserved region Pet191_N PF10203.9 PFH34751.1 - 5.4e-20 71.5 4.1 6.2e-20 71.3 4.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Mtc PF03820.17 PFH34752.1 - 5.6e-89 298.3 0.0 7.6e-89 297.8 0.0 1.2 1 0 0 1 1 1 1 Tricarboxylate carrier DUF5313 PF17240.2 PFH34752.1 - 0.39 11.2 1.7 3.8 8.0 0.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5313) Tic22 PF04278.12 PFH34754.1 - 7.9e-08 32.0 0.0 4.7e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Tic22-like family Shisa PF13908.6 PFH34756.1 - 0.014 15.7 0.2 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF1180 PF06679.12 PFH34756.1 - 0.04 14.3 1.4 0.07 13.5 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) MFS_1 PF07690.16 PFH34758.1 - 1.2e-14 54.0 20.5 1.5e-14 53.7 16.9 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Comm PF15957.5 PFH34758.1 - 0.087 13.2 3.8 0.21 11.9 0.0 2.9 3 0 0 3 3 3 0 Commissureless Pep_deformylase PF01327.21 PFH34759.1 - 1.3e-38 132.1 0.0 1.8e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Ank_2 PF12796.7 PFH34760.1 - 3.6e-32 110.8 0.4 2.2e-16 60.2 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PFH34760.1 - 1.5e-29 101.7 4.3 6.9e-07 29.4 0.0 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PFH34760.1 - 2.1e-28 98.3 0.1 1.1e-09 38.6 0.0 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH34760.1 - 5.1e-26 87.9 0.6 0.00015 22.0 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 PFH34760.1 - 9.2e-23 79.6 6.1 6.4e-06 26.4 0.0 6.7 7 0 0 7 7 7 4 Ankyrin repeat Spore_III_AB PF09548.10 PFH34760.1 - 5.6e-05 23.3 0.3 5.6e-05 23.3 0.3 1.8 2 0 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) Acetyltransf_11 PF13720.6 PFH34760.1 - 1.2 9.7 3.9 0.52 10.8 0.3 2.3 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 KH_1 PF00013.29 PFH34761.1 - 3.8e-29 100.3 14.4 1.9e-11 43.6 2.1 6.9 7 0 0 7 7 7 5 KH domain SLS PF14611.6 PFH34761.1 - 4.8e-07 29.8 2.5 0.23 11.3 0.0 4.3 2 1 2 4 4 4 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 PFH34761.1 - 1.9e-05 24.4 5.7 0.027 14.3 0.2 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 PFH34761.1 - 0.13 12.4 4.5 1.7 8.8 0.4 2.7 2 0 0 2 2 2 0 NusA-like KH domain KH_4 PF13083.6 PFH34761.1 - 0.24 11.3 4.3 5.4 7.0 0.1 3.6 3 0 0 3 3 3 0 KH domain DUF948 PF06103.11 PFH34761.1 - 0.55 10.5 5.3 0.38 11.0 0.8 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) KTI12 PF08433.10 PFH34761.1 - 0.86 9.0 4.4 0.66 9.4 2.7 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SKA1 PF07160.12 PFH34761.1 - 4.1 7.2 9.7 0.47 10.3 4.1 2.1 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 YfhO PF09586.10 PFH34764.1 - 0.32 9.2 0.2 0.42 8.8 0.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO GHMP_kinases_C PF08544.13 PFH34765.1 - 2.3e-11 43.9 1.5 1e-10 41.8 0.2 2.7 3 0 0 3 3 3 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 PFH34765.1 - 0.0012 19.0 3.5 0.0012 19.0 3.5 3.2 2 1 0 2 2 2 1 GHMP kinases N terminal domain Trigger_N PF05697.13 PFH34766.1 - 2.3e-11 44.2 0.0 8.4e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 PFH34766.1 - 3.2e-11 43.5 4.0 8e-11 42.2 4.0 1.6 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus PGA2 PF07543.12 PFH34766.1 - 0.35 10.9 3.5 1 9.3 3.5 1.8 1 0 0 1 1 1 0 Protein trafficking PGA2 EF-hand_7 PF13499.6 PFH34767.1 - 0.00016 22.0 0.4 1 9.8 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH34767.1 - 0.011 15.6 3.8 0.53 10.3 0.2 3.8 4 0 0 4 4 4 0 EF-hand domain YL1 PF05764.13 PFH34767.1 - 0.039 14.1 4.7 0.14 12.3 4.7 1.9 1 0 0 1 1 1 0 YL1 nuclear protein EF-hand_1 PF00036.32 PFH34767.1 - 0.043 13.4 2.8 3.6 7.4 0.2 2.9 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 PFH34767.1 - 0.14 12.0 4.4 22 5.0 0.1 4.4 4 0 0 4 4 4 0 EF-hand domain pair CDC45 PF02724.14 PFH34767.1 - 0.48 8.7 2.8 0.82 7.9 2.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 PFH34767.1 - 1.4 7.0 9.5 2.4 6.3 9.5 1.2 1 0 0 1 1 1 0 Nop14-like family FtsJ PF01728.19 PFH34768.1 - 1.4e-19 70.8 0.0 2.8e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase AP2 PF00847.20 PFH34769.1 - 1.4e-13 50.8 12.3 3.1e-09 36.9 4.4 2.9 2 0 0 2 2 2 2 AP2 domain HAP2-GCS1 PF10699.9 PFH34772.1 - 9.7e-14 51.1 0.1 2.8e-13 49.6 0.1 1.9 1 0 0 1 1 1 1 Male gamete fusion factor DUF326 PF03860.16 PFH34772.1 - 0.077 13.0 2.3 0.18 11.8 2.3 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) Methyltrn_RNA_3 PF02598.17 PFH34773.1 - 1.8e-91 306.6 0.0 2.9e-91 306.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methyltransferase Ribosomal_S5 PF00333.20 PFH34774.1 - 5.3e-14 52.0 0.0 9.2e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 PFH34774.1 - 2.8e-12 45.9 0.0 7.5e-12 44.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain dsrm PF00035.26 PFH34774.1 - 0.034 14.8 0.1 0.22 12.2 0.0 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif PBP1_TM PF14812.6 PFH34774.1 - 0.74 10.2 4.2 2.2 8.7 4.2 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGM_PMM_I PF02878.16 PFH34775.1 - 5.4e-25 87.7 0.0 8.7e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 PFH34775.1 - 5.4e-24 84.6 0.0 1.2e-23 83.5 0.0 1.6 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 PFH34775.1 - 5.4e-10 39.8 0.0 2.7e-09 37.6 0.0 2.3 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 PFH34775.1 - 0.00023 21.3 0.0 0.00069 19.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Filamin PF00630.19 PFH34776.1 - 7.4e-23 81.3 0.3 3.3e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 Filamin/ABP280 repeat Invasin_D3 PF09134.10 PFH34776.1 - 0.05 13.9 0.1 0.41 11.0 0.0 2.3 2 0 0 2 2 2 0 Invasin, domain 3 Tetraspanin PF00335.20 PFH34777.1 - 0.016 14.9 1.6 0.016 14.9 1.6 2.2 2 0 0 2 2 2 0 Tetraspanin family DUF2207 PF09972.9 PFH34777.1 - 1.1 8.0 4.8 14 4.3 5.8 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ZnuA PF01297.17 PFH34778.1 - 0.0002 20.9 2.6 0.00038 20.0 2.6 1.4 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic Exonuc_VII_S PF02609.16 PFH34778.1 - 0.063 13.3 2.6 0.17 12.0 0.7 2.4 2 0 0 2 2 2 0 Exonuclease VII small subunit Smr PF01713.21 PFH34778.1 - 0.069 13.5 0.6 17 5.8 0.2 2.5 2 0 0 2 2 2 0 Smr domain MAD PF05557.13 PFH34778.1 - 0.11 10.9 4.8 0.18 10.1 3.4 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein Baculo_PEP_C PF04513.12 PFH34778.1 - 0.21 11.7 5.7 1.2 9.1 0.4 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fungal_TACC PF12709.7 PFH34778.1 - 0.25 11.8 3.0 0.93 10.0 0.6 2.3 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Leu_zip PF15294.6 PFH34778.1 - 0.31 10.5 4.6 0.21 11.0 1.4 2.0 2 1 0 2 2 2 0 Leucine zipper DUF2203 PF09969.9 PFH34778.1 - 1.1 10.0 11.4 0.25 12.1 4.2 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) HAUS6_N PF14661.6 PFH34778.1 - 1.8 8.1 4.6 0.59 9.7 1.3 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF812 PF05667.11 PFH34778.1 - 2.4 6.9 8.8 2.1 7.1 6.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF812) MCM PF00493.23 PFH34779.1 - 1.5e-84 282.5 0.0 2.2e-84 282.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PFH34779.1 - 4.4e-22 78.3 0.4 2.6e-21 75.8 0.4 2.2 1 1 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PFH34779.1 - 2.3e-14 53.6 0.0 7.7e-12 45.5 0.0 2.6 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 PFH34779.1 - 6e-06 25.8 0.1 0.0019 17.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PFH34779.1 - 0.0042 17.0 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) YL1 PF05764.13 PFH34779.1 - 0.055 13.6 6.2 0.14 12.2 6.2 1.6 1 0 0 1 1 1 0 YL1 nuclear protein AAA_5 PF07728.14 PFH34779.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AGH PF17558.2 PFH34779.1 - 0.3 11.2 2.1 0.76 9.9 2.1 1.6 1 0 0 1 1 1 0 Androgenic gland hormone CDC45 PF02724.14 PFH34779.1 - 0.9 7.8 4.3 1.4 7.1 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Flavokinase PF01687.17 PFH34780.1 - 1.7e-24 86.2 0.0 2.7e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase BAGE PF08180.11 PFH34780.1 - 0.28 11.3 0.0 0.28 11.3 0.0 2.4 2 0 0 2 2 2 0 B melanoma antigen family Leo1 PF04004.13 PFH34781.1 - 8e-11 42.1 0.1 2.2e-10 40.6 0.1 1.7 1 1 0 1 1 1 1 Leo1-like protein PseudoU_synth_2 PF00849.22 PFH34782.1 - 4.2e-09 36.7 0.0 7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Cupin_4 PF08007.12 PFH34782.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein HUN PF08729.10 PFH34783.1 - 0.00026 20.9 0.7 0.001 19.0 0.7 2.0 1 0 0 1 1 1 1 HPC2 and ubinuclein domain ABC_tran PF00005.27 PFH34784.1 - 8.6e-37 126.7 0.0 2.6e-17 63.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 PFH34784.1 - 7e-15 54.6 8.9 9.2e-15 54.2 6.0 2.5 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 PFH34784.1 - 3.5e-11 43.5 5.0 0.013 15.4 0.0 4.2 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PFH34784.1 - 8.1e-11 41.8 3.3 0.0017 17.9 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 PFH34784.1 - 7.8e-08 32.7 0.0 4.1e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 PFH34784.1 - 5.1e-07 29.3 0.1 0.0057 16.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 PFH34784.1 - 8.1e-07 29.1 0.0 0.12 12.1 0.0 3.3 4 0 0 4 4 3 2 AAA ATPase domain Fer4 PF00037.27 PFH34784.1 - 2.3e-06 27.2 4.2 2.3e-06 27.2 4.2 2.4 3 0 0 3 3 1 1 4Fe-4S binding domain Rad17 PF03215.15 PFH34784.1 - 4.6e-06 26.7 0.0 0.0037 17.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 PFH34784.1 - 8.3e-06 26.3 0.0 0.017 15.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 PFH34784.1 - 8.6e-06 25.8 0.0 0.012 15.5 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase Fer4_6 PF12837.7 PFH34784.1 - 8.7e-06 25.6 13.8 5.3e-05 23.1 3.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_5 PF07728.14 PFH34784.1 - 4.3e-05 23.5 0.2 0.016 15.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Fer4_7 PF12838.7 PFH34784.1 - 0.00042 20.9 5.6 0.002 18.7 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_23 PF13476.6 PFH34784.1 - 0.00068 20.2 0.0 0.16 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 PFH34784.1 - 0.00071 20.0 0.0 0.7 10.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 PFH34784.1 - 0.0011 18.9 0.0 0.44 10.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 PFH34784.1 - 0.0017 18.4 0.4 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 PFH34784.1 - 0.002 18.5 0.0 4 7.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Fer4_2 PF12797.7 PFH34784.1 - 0.0025 17.8 1.1 0.0025 17.8 1.1 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.6 PFH34784.1 - 0.0031 17.7 0.0 0.62 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PFH34784.1 - 0.0056 16.9 0.0 3.1 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 PFH34784.1 - 0.006 16.7 11.6 0.012 15.7 11.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain SRP54 PF00448.22 PFH34784.1 - 0.0062 16.2 0.8 1.7 8.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 PFH34784.1 - 0.0078 16.8 0.0 2.1 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PFH34784.1 - 0.0087 15.8 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.6 PFH34784.1 - 0.011 15.8 11.7 0.024 14.8 11.7 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 PFH34784.1 - 0.012 15.7 1.8 0.012 15.7 1.8 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_7 PF12775.7 PFH34784.1 - 0.014 14.9 0.0 0.77 9.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 PFH34784.1 - 0.026 13.9 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 PFH34784.1 - 0.031 14.3 0.1 9.7 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 PFH34784.1 - 0.031 13.4 0.2 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 PFH34784.1 - 0.032 14.0 0.2 7.2 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 PFH34784.1 - 0.032 13.4 0.0 1.2 8.3 0.0 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Thymidylate_kin PF02223.17 PFH34784.1 - 0.038 13.7 0.0 3.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase MeaB PF03308.16 PFH34784.1 - 0.039 12.9 0.1 0.94 8.4 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 PFH34784.1 - 0.045 13.0 0.2 1.3 8.3 0.0 2.5 3 0 0 3 3 2 0 Zeta toxin NB-ARC PF00931.22 PFH34784.1 - 0.047 12.9 0.0 4.2 6.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_27 PF13514.6 PFH34784.1 - 0.059 13.0 0.0 3.5 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_17 PF13534.6 PFH34784.1 - 0.066 13.8 0.2 0.066 13.8 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain TniB PF05621.11 PFH34784.1 - 0.073 12.5 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 PFH34784.1 - 0.091 12.8 0.0 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE VirE PF05272.11 PFH34784.1 - 0.11 12.2 0.0 8.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E SbcCD_C PF13558.6 PFH34784.1 - 0.11 12.7 0.0 13 6.1 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_PrkA PF08298.11 PFH34784.1 - 0.12 11.2 0.0 8.5 5.2 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain MukB PF04310.12 PFH34784.1 - 0.15 11.9 0.2 20 4.9 0.0 2.6 3 0 0 3 3 2 0 MukB N-terminal Fer4_8 PF13183.6 PFH34784.1 - 0.16 12.5 6.6 0.21 12.0 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_13 PF13166.6 PFH34784.1 - 0.17 10.5 0.6 0.31 9.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 PFH34784.1 - 0.21 11.5 0.3 18 5.2 0.0 2.6 2 0 0 2 2 2 0 NTPase Fer4_4 PF12800.7 PFH34784.1 - 6.7 7.5 15.3 0.59 10.8 3.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain DUF4464 PF14713.6 PFH34785.1 - 2e-87 292.5 0.5 2.2e-87 292.3 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) 5_nucleotid_C PF02872.18 PFH34786.1 - 3e-30 105.5 0.0 4.7e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PFH34786.1 - 2.9e-08 34.4 0.1 4.8e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.16 PFH34787.1 - 1.2e-34 119.8 34.0 7.4e-33 113.9 19.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PFH34787.1 - 2e-06 26.9 5.6 2e-06 26.9 5.6 2.7 2 1 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 PFH34787.1 - 2.8e-05 22.6 3.0 0.0015 16.9 0.5 2.9 2 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 PFH34787.1 - 0.0033 16.3 3.0 0.012 14.4 3.0 2.0 1 1 0 1 1 1 1 MFS_1 like family ECF_trnsprt PF12822.7 PFH34787.1 - 0.056 13.5 8.2 1.2 9.2 4.7 3.2 1 1 1 2 2 2 0 ECF transporter, substrate-specific component Gly-zipper_Omp PF13488.6 PFH34787.1 - 1.4 8.9 7.6 0.36 10.9 2.5 2.4 2 0 0 2 2 2 0 Glycine zipper DUF3094 PF11293.8 PFH34787.1 - 8.8 6.1 6.5 1.4 8.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) DTW PF03942.15 PFH34788.1 - 4.1e-16 59.3 0.0 6.9e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 DTW domain EIN3 PF04873.13 PFH34789.1 - 0.051 12.9 22.5 26 4.0 0.3 7.8 8 0 0 8 8 8 0 Ethylene insensitive 3 DUF2968 PF11180.8 PFH34790.1 - 0.27 10.8 4.2 0.7 9.5 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) ADIP PF11559.8 PFH34790.1 - 0.75 9.9 9.4 4 7.5 9.4 2.2 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding IRK PF01007.20 PFH34791.1 - 3.6e-08 33.3 1.9 6.2e-08 32.6 1.9 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 PFH34791.1 - 5.5e-08 32.6 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 PFH34791.1 - 0.024 14.6 5.6 0.051 13.5 5.6 1.6 1 1 0 1 1 1 0 Ion channel Ion_trans PF00520.31 PFH34791.1 - 0.07 12.3 6.9 1.1 8.4 5.8 2.1 1 1 1 2 2 2 0 Ion transport protein OSCP PF00213.18 PFH34792.1 - 2.1e-47 161.4 0.8 2.5e-47 161.2 0.8 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit EF-hand_6 PF13405.6 PFH34793.1 - 3.9e-15 54.4 0.7 3.3e-08 32.8 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 PFH34793.1 - 3e-14 53.2 0.6 9.4e-11 42.0 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PFH34793.1 - 7.1e-14 50.2 0.5 6.7e-08 31.5 0.2 3.7 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 PFH34793.1 - 1.5e-09 36.9 0.0 1.6e-05 24.1 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PFH34793.1 - 1.6e-09 37.5 1.1 9.8e-06 25.3 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PFH34793.1 - 0.0026 18.1 0.1 0.0048 17.2 0.1 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 PFH34793.1 - 0.028 14.3 0.1 0.065 13.1 0.1 1.7 1 1 0 1 1 1 0 EF hand tRNA-synt_2e PF02091.15 PFH34793.1 - 0.042 13.1 0.7 0.12 11.6 0.5 1.8 1 1 1 2 2 2 0 Glycyl-tRNA synthetase alpha subunit EF-hand_9 PF14658.6 PFH34793.1 - 0.11 12.9 0.1 3.1 8.2 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 PFH34794.1 - 1.1e-08 34.8 0.0 2.5e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 PFH34794.1 - 1.6e-06 28.5 0.1 4.4e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PFH34794.1 - 6.9e-05 22.2 0.0 0.00022 20.6 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 PFH34794.1 - 0.00023 20.5 0.3 0.0013 18.2 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 PFH34794.1 - 0.0014 18.4 0.1 0.0083 16.0 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain Ribosomal_L6 PF00347.23 PFH34795.1 - 4.1e-32 110.7 2.5 2.1e-17 63.5 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Caf4 PF11615.8 PFH34796.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 CCR4-associated factor 4 Pribosyltran_N PF13793.6 PFH34797.1 - 1.1e-34 118.8 0.0 3.6e-34 117.2 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 PFH34797.1 - 1.7e-27 96.7 0.1 3.6e-27 95.6 0.1 1.5 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 PFH34797.1 - 0.0047 16.4 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Med10 PF09748.9 PFH34798.1 - 1.5e-05 24.9 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex CDC45 PF02724.14 PFH34798.1 - 0.016 13.5 0.4 0.021 13.1 0.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Par3_HAL_N_term PF12053.8 PFH34798.1 - 0.056 13.7 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins E1-E2_ATPase PF00122.20 PFH34799.1 - 1.2e-46 158.5 1.2 8.5e-45 152.5 0.1 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 PFH34799.1 - 2.3e-18 67.2 0.4 4.4e-18 66.3 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PFH34799.1 - 1.1e-09 37.8 0.0 3.8e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PFH34799.1 - 4.4e-05 23.4 0.6 7.9e-05 22.5 0.6 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PFH34799.1 - 0.00015 21.7 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Ribosomal_L2_C PF03947.18 PFH34799.1 - 0.16 12.2 1.6 21 5.3 0.1 2.9 3 0 0 3 3 3 0 Ribosomal Proteins L2, C-terminal domain RAB3GAP2_C PF14656.6 PFH34799.1 - 0.17 10.1 0.5 0.29 9.3 0.5 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Phage_holin_5_2 PF16079.5 PFH34799.1 - 2.3 8.6 4.8 15 6.0 0.2 3.6 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V TSP_1 PF00090.19 PFH34800.1 - 0.00048 20.3 4.5 0.0015 18.7 4.5 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain ETRAMP PF09716.10 PFH34800.1 - 0.035 14.2 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) LRR_6 PF13516.6 PFH34801.1 - 0.031 14.3 3.6 1.2e+02 3.2 0.0 6.2 7 0 0 7 7 7 0 Leucine Rich repeat Repressor_Mnt PF11423.8 PFH34801.1 - 0.93 9.3 3.2 2.9 7.7 3.2 1.9 1 0 0 1 1 1 0 Regulatory protein Mnt zf-met2 PF12907.7 PFH34802.1 - 8.4e-15 54.6 6.0 1.2e-14 54.1 6.0 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 PFH34802.1 - 5e-09 36.9 4.4 7e-09 36.4 4.4 1.2 1 0 0 1 1 1 1 4F5 protein family Elf1 PF05129.13 PFH34802.1 - 0.0092 16.0 0.9 0.013 15.5 0.9 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-C2H2_12 PF18658.1 PFH34802.1 - 0.0098 15.4 0.2 0.014 14.9 0.2 1.2 1 0 0 1 1 1 1 Zinc-finger C2H2-type zf-C2H2_4 PF13894.6 PFH34802.1 - 0.089 13.7 0.6 0.18 12.7 0.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Ribosomal_S6 PF01250.17 PFH34804.1 - 8.2e-17 61.3 0.0 1.1e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 RVT_N PF13655.6 PFH34804.1 - 0.027 14.7 0.9 0.074 13.3 0.9 1.8 1 1 0 1 1 1 0 N-terminal domain of reverse transcriptase Nup54_C PF18437.1 PFH34804.1 - 0.034 14.0 1.9 0.1 12.5 2.0 1.7 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain NYD-SP28_assoc PF14775.6 PFH34805.1 - 7.8e-07 29.1 0.2 7.8e-07 29.1 0.2 3.1 3 0 0 3 3 3 1 Sperm tail C-terminal domain NYD-SP28 PF14772.6 PFH34805.1 - 0.00084 19.4 7.5 0.00084 19.4 7.5 5.0 2 1 4 6 6 6 1 Sperm tail COG2 PF06148.11 PFH34805.1 - 8.3 6.5 14.9 12 6.0 3.7 4.0 2 2 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 FUSC_2 PF13515.6 PFH34806.1 - 3.8e-11 43.2 11.5 3.8e-11 43.2 11.5 3.9 2 2 2 4 4 4 1 Fusaric acid resistance protein-like YtxH PF12732.7 PFH34806.1 - 0.097 13.2 0.3 0.44 11.1 0.1 2.2 2 0 0 2 2 2 0 YtxH-like protein ALMT PF11744.8 PFH34806.1 - 0.17 10.7 8.1 0.0069 15.3 1.6 1.9 2 0 0 2 2 2 0 Aluminium activated malate transporter ArAE_1 PF06081.11 PFH34806.1 - 9.4 6.4 8.9 1.1 9.4 0.1 3.1 3 0 0 3 3 3 0 Aromatic acid exporter family member 1 EF-hand_7 PF13499.6 PFH34809.1 - 0.0098 16.3 0.0 0.81 10.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair Peptidase_M99 PF17033.5 PFH34809.1 - 0.028 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Carboxypeptidase controlling helical cell shape catalytic Pkinase PF00069.25 PFH34810.1 - 2.3e-73 246.8 0.0 3.1e-73 246.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34810.1 - 6.5e-28 97.7 0.0 9.5e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PFH34810.1 - 0.18 11.4 0.1 0.31 10.6 0.1 1.3 1 0 0 1 1 1 0 RIO1 family PUA_3 PF17785.1 PFH34812.1 - 6.1e-10 38.8 0.0 2.5e-09 36.8 0.0 2.0 1 1 0 1 1 1 1 PUA-like domain Methyltrans_SAM PF10672.9 PFH34812.1 - 4.8e-07 29.2 0.0 7.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Met_10 PF02475.16 PFH34812.1 - 8.6e-05 22.4 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 PFH34812.1 - 0.00055 19.6 0.0 0.00091 18.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 S1-P1_nuclease PF02265.16 PFH34813.1 - 3.4e-30 105.7 0.6 6e-09 36.1 0.0 3.1 3 0 0 3 3 3 3 S1/P1 Nuclease zf-RING_2 PF13639.6 PFH34814.1 - 1.1e-11 44.9 8.4 2.3e-11 43.8 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PFH34814.1 - 7.9e-09 35.7 8.0 7.9e-09 35.7 8.0 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PFH34814.1 - 2.4e-08 33.7 7.0 5.9e-08 32.4 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PFH34814.1 - 2.2e-06 27.3 2.8 4.9e-06 26.2 2.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 PFH34814.1 - 1.3e-05 24.9 6.9 2.7e-05 24.0 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH34814.1 - 5.3e-05 23.2 6.2 0.00011 22.1 6.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 PFH34814.1 - 7e-05 22.8 1.4 0.00016 21.7 1.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 PFH34814.1 - 0.00082 19.5 3.8 0.00082 19.5 3.8 2.0 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_5 PF14634.6 PFH34814.1 - 0.0035 17.3 6.7 0.0035 17.3 6.7 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PFH34814.1 - 0.0085 15.9 4.7 0.0085 15.9 4.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PFH34814.1 - 0.011 15.4 4.0 0.029 14.0 4.0 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DinB_2 PF12867.7 PFH34814.1 - 0.013 16.0 0.3 0.47 11.0 0.0 3.1 3 1 0 3 3 3 0 DinB superfamily Prok-RING_4 PF14447.6 PFH34814.1 - 0.026 14.4 7.6 0.087 12.7 7.6 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 PFH34814.1 - 0.064 13.1 2.8 0.12 12.2 2.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 PFH34814.1 - 0.2 11.5 0.1 0.73 9.7 0.0 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif Apt1 PF10351.9 PFH34814.1 - 0.8 8.5 3.8 1.1 8.1 3.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RINGv PF12906.7 PFH34814.1 - 1.2 9.3 8.6 2.5 8.3 8.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 PFH34814.1 - 1.7 8.7 4.2 3.9 7.6 4.2 1.6 1 0 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 PFH34814.1 - 2.1 8.7 5.2 6.4 7.2 5.2 1.8 1 0 0 1 1 1 0 RING-like domain TF_Zn_Ribbon PF08271.12 PFH34814.1 - 2.6 7.6 6.9 0.085 12.4 0.7 1.8 2 0 0 2 2 1 0 TFIIB zinc-binding Beta-Casp PF10996.8 PFH34815.1 - 1.2e-25 89.9 0.0 2.6e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain CPSF73-100_C PF11718.8 PFH34815.1 - 5.3e-18 65.4 0.0 1e-17 64.4 0.0 1.5 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term RMMBL PF07521.12 PFH34815.1 - 2.1e-17 62.8 0.0 4.4e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 PFH34815.1 - 4.9e-15 55.5 0.0 8.6e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 PFH34815.1 - 4.7e-13 49.6 3.5 2.8e-12 47.0 0.5 3.3 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PFH34815.1 - 3.7e-05 23.3 0.2 0.0015 18.1 0.2 2.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 PFH34815.1 - 0.00091 19.1 0.0 0.0034 17.3 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 PFH34815.1 - 0.0058 15.9 0.0 0.0095 15.2 0.0 1.2 1 0 0 1 1 1 1 Putative beta-lactamase-like family Wtap PF17098.5 PFH34816.1 - 0.01 15.8 26.5 0.028 14.4 26.5 1.7 1 0 0 1 1 1 0 WTAP/Mum2p family DUF4407 PF14362.6 PFH34816.1 - 0.016 14.6 0.6 0.016 14.6 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) BPL_N PF09825.9 PFH34816.1 - 9 5.3 8.7 14 4.6 8.7 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal CAP_GLY PF01302.25 PFH34817.1 - 4.1e-15 55.5 0.0 9.5e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 PFH34817.1 - 5.1e-08 33.3 0.0 9.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_4 PF12799.7 PFH34817.1 - 2.1e-06 28.0 0.7 0.11 12.9 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) PRP38 PF03371.15 PFH34818.1 - 4.7e-52 176.4 0.2 7.5e-52 175.7 0.2 1.2 1 0 0 1 1 1 1 PRP38 family Steroid_dh PF02544.16 PFH34819.1 - 6.5e-34 117.1 1.5 6.5e-34 117.1 1.5 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 PFH34819.1 - 6.7e-05 22.6 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 PFH34819.1 - 0.0017 19.0 0.0 0.0026 18.4 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD DnaJ PF00226.31 PFH34822.1 - 6.4e-17 61.4 0.2 2.8e-16 59.4 0.2 2.2 1 0 0 1 1 1 1 DnaJ domain SabA_adhesion PF18304.1 PFH34822.1 - 0.00053 19.3 0.4 0.00081 18.7 0.4 1.2 1 0 0 1 1 1 1 SabA N-terminal extracellular adhesion domain ArAE_2_N PF10337.9 PFH34822.1 - 0.75 8.8 7.9 1.3 7.9 7.9 1.4 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Fasciclin PF02469.22 PFH34823.1 - 3.1e-09 37.1 0.0 0.014 15.7 0.0 3.1 3 0 0 3 3 3 3 Fasciclin domain HTH_Tnp_1 PF01527.20 PFH34825.1 - 0.0027 18.0 0.1 0.0034 17.7 0.1 1.2 1 0 0 1 1 1 1 Transposase HTH_DeoR PF08220.12 PFH34825.1 - 0.015 15.0 0.1 0.033 13.9 0.0 1.5 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain MerR_1 PF13411.6 PFH34825.1 - 0.023 14.8 0.1 0.062 13.4 0.0 1.8 2 0 0 2 2 2 0 MerR HTH family regulatory protein LRR_4 PF12799.7 PFH34826.1 - 5.1e-15 55.3 1.0 3.6e-07 30.4 0.3 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH34826.1 - 4.9e-07 29.4 6.3 2.3e-06 27.3 0.5 3.0 2 1 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 PFH34826.1 - 9.1e-06 25.3 0.3 0.00018 21.0 0.3 2.5 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 PFH34826.1 - 0.0014 18.9 5.1 17 6.4 0.1 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 PFH34826.1 - 0.0025 17.7 1.7 11 6.4 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich repeat Kinesin PF00225.23 PFH34827.1 - 7.1e-99 330.9 0.9 9.7e-99 330.4 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PFH34827.1 - 1.6e-44 151.4 0.1 1.6e-44 151.4 0.1 3.3 3 0 0 3 3 3 1 Microtubule binding Spc24 PF08286.11 PFH34827.1 - 0.023 15.0 1.3 0.023 15.0 1.3 6.9 5 3 2 7 7 7 0 Spc24 subunit of Ndc80 Shugoshin_N PF07558.11 PFH34827.1 - 0.049 13.5 13.0 0.22 11.4 1.1 4.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 PFH34827.1 - 5.1 7.5 30.5 0.72 10.2 1.6 7.9 7 1 0 7 7 7 0 TSC-22/dip/bun family Dimer_Tnp_hAT PF05699.14 PFH34828.1 - 8.6e-06 25.5 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 PFH34829.1 - 9.4e-09 35.2 0.2 1.8e-08 34.2 0.2 1.5 1 0 0 1 1 1 1 BED zinc finger Cullin PF00888.22 PFH34831.1 - 2.8e-19 69.2 0.0 1.4e-11 43.8 0.0 4.3 4 1 0 4 4 4 3 Cullin family Cullin_Nedd8 PF10557.9 PFH34831.1 - 1.5e-09 37.7 0.1 0.00014 21.8 0.1 2.4 2 0 0 2 2 2 2 Cullin protein neddylation domain Patched PF02460.18 PFH34832.1 - 1.4e-89 301.3 0.0 1.3e-50 172.3 0.0 2.8 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 PFH34832.1 - 2.3e-28 99.0 5.0 2.3e-28 99.0 5.0 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation HHH PF00633.23 PFH34835.1 - 2.1e-06 27.3 0.0 5.5e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HhH-GPD PF00730.25 PFH34835.1 - 0.00019 21.9 0.0 0.00099 19.5 0.0 2.1 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein PRT_C PF08372.10 PFH34836.1 - 0.039 13.7 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal CHCH PF06747.13 PFH34838.1 - 0.00043 20.3 10.7 0.037 14.2 1.0 2.4 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.10 PFH34838.1 - 0.0041 17.1 9.9 0.01 15.8 1.8 2.6 2 1 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 PFH34838.1 - 0.024 14.4 6.5 0.21 11.4 0.5 3.0 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 PFH34838.1 - 1 9.7 8.4 4.2 7.8 3.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 PFH34838.1 - 1.2 9.2 11.4 0.52 10.4 1.7 2.9 2 1 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX6B PF02297.17 PFH34838.1 - 2.4 8.4 7.4 6.1 7.2 7.4 1.7 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.12 PFH34838.1 - 4.7 7.5 7.2 0.78 10.0 0.3 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Methyltransf_15 PF09445.10 PFH34839.1 - 6.4e-25 87.6 0.0 2.2e-24 85.9 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Ribosomal_L35p PF01632.19 PFH34840.1 - 9.9e-12 45.2 9.7 2.2e-11 44.1 9.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L35 PAP_assoc PF03828.19 PFH34841.1 - 6.2e-07 29.5 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 PFH34841.1 - 0.00051 20.3 0.0 0.01 16.1 0.0 2.4 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nop14 PF04147.12 PFH34841.1 - 0.14 10.3 6.8 0.61 8.2 3.5 2.2 2 0 0 2 2 2 0 Nop14-like family CENP-F_leu_zip PF10473.9 PFH34842.1 - 2.1 8.3 11.9 0.77 9.8 4.2 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DSHCT PF08148.12 PFH34843.1 - 2.6e-43 147.5 0.0 5.3e-43 146.5 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 PFH34843.1 - 6.1e-16 58.7 0.0 1.4e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH34843.1 - 1.6e-06 28.4 0.0 6.6e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH34843.1 - 2.4e-05 24.4 0.0 6.2e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit rRNA_proc-arch PF13234.6 PFH34843.1 - 0.00066 19.7 0.0 0.0024 17.9 0.0 1.8 1 1 0 1 1 1 1 rRNA-processing arch domain Peptidase_M50B PF13398.6 PFH34844.1 - 3.8e-58 196.4 20.4 4.7e-58 196.1 20.4 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M3 PF01432.20 PFH34844.1 - 0.36 10.0 0.1 0.51 9.5 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M3 Biotin_lipoyl PF00364.22 PFH34845.1 - 6.1e-18 64.4 1.1 9.6e-18 63.8 1.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Notch PF00066.17 PFH34846.1 - 5.9e-44 148.2 105.2 5.2e-08 33.2 10.3 6.2 4 1 2 6 6 6 6 LNR domain UFD1 PF03152.14 PFH34847.1 - 3.8e-21 75.3 0.0 1.8e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 Tmemb_185A PF10269.9 PFH34847.1 - 0.11 12.2 0.3 0.17 11.6 0.3 1.2 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein 4HBT PF03061.22 PFH34848.1 - 7.6e-07 29.4 1.4 2.1e-06 28.0 0.7 2.1 2 0 0 2 2 2 1 Thioesterase superfamily ATP_bind_1 PF03029.17 PFH34849.1 - 2.9e-70 236.8 0.0 4.1e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 PFH34849.1 - 0.0002 20.4 0.8 0.0028 16.7 0.3 2.5 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 PFH34849.1 - 0.00023 21.0 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PFH34849.1 - 0.00076 19.3 0.9 0.001 18.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain CbiA PF01656.23 PFH34849.1 - 0.00078 19.5 0.0 0.0011 19.1 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 PFH34849.1 - 0.00083 19.5 0.1 0.00083 19.5 0.1 2.1 2 1 0 2 2 1 1 AAA domain SRP54 PF00448.22 PFH34849.1 - 0.00088 18.9 1.3 0.098 12.3 0.1 3.0 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 PFH34849.1 - 0.001 19.6 0.0 0.0021 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PFH34849.1 - 0.0018 18.7 0.3 0.005 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 PFH34849.1 - 0.0026 17.7 0.0 0.0058 16.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.23 PFH34849.1 - 0.0035 17.4 0.0 0.021 14.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 PFH34849.1 - 0.0044 16.6 0.1 0.97 9.0 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 PFH34849.1 - 0.0082 15.4 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain FeoB_N PF02421.18 PFH34849.1 - 0.0091 15.5 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RNA_helicase PF00910.22 PFH34849.1 - 0.0093 16.3 0.0 1 9.8 0.0 2.6 2 1 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 PFH34849.1 - 0.021 14.7 0.1 11 5.9 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase AAA_31 PF13614.6 PFH34849.1 - 0.027 14.4 0.0 3.5 7.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 PFH34849.1 - 0.033 14.1 0.2 0.21 11.5 0.2 2.0 1 1 0 1 1 1 0 NTPase AAA_23 PF13476.6 PFH34849.1 - 0.034 14.7 0.2 1.8 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain U1snRNP70_N PF12220.8 PFH34849.1 - 0.039 14.6 0.4 0.074 13.7 0.4 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AAA_19 PF13245.6 PFH34849.1 - 0.055 13.8 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 PFH34849.1 - 0.063 13.3 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 PFH34849.1 - 0.066 12.7 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 1 0 Poxvirus A32 protein AAA_28 PF13521.6 PFH34849.1 - 0.076 13.3 0.1 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 PFH34849.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 PFH34849.1 - 0.11 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 PFH34849.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 PFH34849.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PFH34849.1 - 0.19 12.3 0.0 0.51 10.9 0.0 1.7 2 0 0 2 2 1 0 ABC transporter BAF1_ABF1 PF04684.13 PFH34849.1 - 0.24 10.4 2.3 0.31 10.0 2.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF463 PF04317.12 PFH34849.1 - 0.27 10.1 0.1 0.27 10.1 0.1 2.1 2 0 0 2 2 2 0 YcjX-like family, DUF463 RabGAP-TBC PF00566.18 PFH34851.1 - 2.3e-49 168.0 0.1 3.4e-49 167.4 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain adh_short PF00106.25 PFH34852.1 - 0.0039 16.7 1.7 0.21 11.0 0.1 2.7 3 1 0 3 3 3 2 short chain dehydrogenase Epimerase PF01370.21 PFH34852.1 - 0.0055 16.2 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Pro_isomerase PF00160.21 PFH34853.1 - 5.6e-45 153.5 0.1 6.5e-45 153.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4325 PF14213.6 PFH34853.1 - 0.15 11.8 0.1 0.59 9.9 0.1 2.1 2 0 0 2 2 2 0 STAS-like domain of unknown function (DUF4325) CLAMP PF14769.6 PFH34854.1 - 1.4e-26 92.8 1.9 1.9e-26 92.4 1.9 1.2 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 GCP_C_terminal PF04130.13 PFH34855.1 - 6.2e-14 52.2 1.7 1.5e-08 34.5 0.4 3.5 2 2 0 2 2 2 2 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PFH34855.1 - 1.8e-06 27.8 0.0 0.1 12.2 0.0 3.2 3 0 0 3 3 3 2 Gamma tubulin complex component N-terminal CDC27 PF09507.10 PFH34855.1 - 2 7.7 10.0 6.8 6.0 10.0 1.9 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Gly-rich_Ago1 PF12764.7 PFH34856.1 - 0.09 13.6 0.3 0.09 13.6 0.3 1.8 2 0 0 2 2 2 0 Glycine-rich region of argonaut SNF PF00209.18 PFH34858.1 - 1.2e-17 63.9 17.7 1.1e-10 40.9 10.6 2.1 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family zf-MYND PF01753.18 PFH34859.1 - 8.5e-06 25.8 10.2 1.8e-05 24.7 10.2 1.5 1 0 0 1 1 1 1 MYND finger PPR PF01535.20 PFH34860.1 - 2 8.8 7.6 30 5.2 0.0 5.1 6 0 0 6 6 6 0 PPR repeat RAP PF08373.10 PFH34861.1 - 1.3e-22 79.6 0.2 2e-22 79.0 0.2 1.3 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 PFH34861.1 - 0.0017 18.5 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 REase_MTES_1575 Senescence PF06911.12 PFH34861.1 - 0.051 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Senescence-associated protein Nsp1_C PF05064.13 PFH34861.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region Glyco_hydro2_C5 PF18565.1 PFH34861.1 - 0.17 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 MMtag PF10159.9 PFH34861.1 - 0.4 11.0 2.0 0.54 10.6 0.4 2.0 2 0 0 2 2 2 0 Multiple myeloma tumor-associated FKBP_C PF00254.28 PFH34862.1 - 8.6e-24 83.7 0.0 1.7e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RR_TM4-6 PF06459.12 PFH34862.1 - 3.5 7.4 10.0 6.1 6.6 10.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SRP-alpha_N PF04086.13 PFH34862.1 - 5.4 6.8 14.0 9 6.1 14.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GREB1 PF15782.5 PFH34862.1 - 9.2 3.2 5.9 12 2.9 5.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Exo_endo_phos PF03372.23 PFH34863.1 - 6.2e-13 48.8 0.1 1.2e-12 47.9 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhlB PF12300.8 PFH34863.1 - 7.3 6.7 20.6 3.6 7.7 1.0 2.9 2 1 1 3 3 3 0 ATP-dependent RNA helicase RhlB HEAT_EZ PF13513.6 PFH34864.1 - 1.4e-23 82.9 18.9 2.8e-10 40.5 0.1 10.9 9 1 2 11 11 11 5 HEAT-like repeat HEAT PF02985.22 PFH34864.1 - 6.5e-22 75.7 25.0 2.8e-06 27.1 0.0 11.7 12 0 0 12 12 11 6 HEAT repeat HEAT_2 PF13646.6 PFH34864.1 - 1.1e-15 57.8 10.3 0.00047 20.5 1.0 8.0 5 4 4 9 9 9 4 HEAT repeats Cnd1 PF12717.7 PFH34864.1 - 2.3e-12 47.3 0.0 0.00047 20.2 0.0 5.2 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 PFH34864.1 - 5e-08 32.7 5.4 0.28 11.3 0.1 6.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 PFH34864.1 - 5.5e-08 32.6 0.5 3.3e-06 26.9 0.0 3.8 3 1 1 4 4 4 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 PFH34864.1 - 1.7e-05 25.3 0.0 0.87 10.2 0.0 4.7 3 2 1 4 4 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 PFH34864.1 - 8.5e-05 22.2 1.8 5.2 6.6 0.0 5.7 4 2 1 6 6 6 1 CLASP N terminal Adaptin_N PF01602.20 PFH34864.1 - 0.00044 19.0 0.0 0.41 9.1 0.1 3.6 3 1 0 3 3 3 1 Adaptin N terminal region DUF3437 PF11919.8 PFH34864.1 - 0.0014 18.5 0.1 0.13 12.2 0.0 4.1 4 1 1 5 5 5 1 Domain of unknown function (DUF3437) BP28CT PF08146.12 PFH34864.1 - 0.024 14.5 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 BP28CT (NUC211) domain Methyltransf_8 PF05148.15 PFH34867.1 - 1.4e-62 211.4 0.0 1.9e-61 207.7 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_25 PF13649.6 PFH34867.1 - 5e-05 23.9 0.3 0.0031 18.2 0.0 3.0 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 PFH34867.1 - 8.6e-05 23.1 0.2 0.00067 20.3 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH34867.1 - 0.25 12.1 2.2 8.1 7.3 0.0 3.7 2 2 2 4 4 4 0 Methyltransferase domain Glycos_transf_2 PF00535.26 PFH34868.1 - 1.7e-10 41.0 0.1 0.0015 18.3 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 2 RRF PF01765.19 PFH34869.1 - 1e-29 103.6 0.9 1e-29 103.6 0.9 1.9 2 1 0 2 2 2 1 Ribosome recycling factor Thioredoxin PF00085.20 PFH34870.1 - 0.0003 20.7 0.0 0.00067 19.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin tRNA-synt_1 PF00133.22 PFH34871.1 - 2.4e-56 191.2 0.0 8.5e-18 63.9 0.0 5.4 5 1 0 5 5 5 5 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PFH34871.1 - 2.5e-10 40.5 0.0 2.1e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PFH34871.1 - 1.2e-06 27.6 0.0 0.29 9.8 0.0 3.8 4 0 0 4 4 4 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 PFH34871.1 - 0.0027 18.0 5.1 0.0067 16.7 5.1 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm ABC_tran_CTD PF16326.5 PFH34871.1 - 0.028 14.6 1.3 0.071 13.4 1.3 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain ADIP PF11559.8 PFH34871.1 - 8.7 6.4 6.1 15 5.6 6.1 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Pex26 PF07163.12 PFH34873.1 - 0.087 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Pex26 protein NMD3 PF04981.13 PFH34874.1 - 3.2e-65 220.0 6.9 4.5e-65 219.5 6.9 1.2 1 0 0 1 1 1 1 NMD3 family CpXC PF14353.6 PFH34874.1 - 1.6 8.8 5.6 2.1 8.4 0.1 2.7 1 1 1 2 2 2 0 CpXC protein Peptidase_U4 PF03419.13 PFH34876.1 - 0.019 14.3 2.1 0.028 13.7 2.1 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Trep_Strep PF09605.10 PFH34876.1 - 0.058 13.4 1.4 0.14 12.2 1.4 1.5 1 1 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Glucos_trans_II PF14264.6 PFH34876.1 - 0.19 11.0 5.3 1.4 8.2 5.4 1.9 1 1 0 1 1 1 0 Glucosyl transferase GtrII Proteasome PF00227.26 PFH34878.1 - 2.6e-37 128.2 0.0 4.2e-37 127.5 0.0 1.3 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PFH34878.1 - 1.2e-12 47.3 0.1 2e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature OTU PF02338.19 PFH34879.1 - 0.0027 18.2 0.0 0.0042 17.6 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PFH34879.1 - 0.0097 15.4 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain Nop25 PF09805.9 PFH34880.1 - 1.9e-09 38.1 15.6 1.9e-09 38.1 15.6 3.3 2 1 0 3 3 3 1 Nucleolar protein 12 (25kDa) BBS2_C PF14782.6 PFH34880.1 - 0.16 10.7 1.9 0.23 10.2 1.9 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal RabGAP-TBC PF00566.18 PFH34881.1 - 9.4e-31 107.1 0.0 1.3e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 PFH34881.1 - 0.021 15.3 0.0 0.74 10.4 0.0 2.8 2 1 0 2 2 2 0 Rhodanese-like domain KIND PF16474.5 PFH34882.1 - 0.022 14.7 1.8 0.031 14.2 1.8 1.2 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Exo5 PF09810.9 PFH34882.1 - 0.027 14.0 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease DUF4611 PF15387.6 PFH34882.1 - 0.92 9.8 8.4 1.3 9.2 7.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Rad51 PF08423.11 PFH34883.1 - 7.8e-115 382.5 0.2 1.3e-114 381.8 0.1 1.4 2 0 0 2 2 2 1 Rad51 RecA PF00154.21 PFH34883.1 - 1.4e-10 41.1 0.1 2e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 PFH34883.1 - 6.9e-08 32.3 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 PFH34883.1 - 3.6e-06 27.5 0.6 1.1e-05 25.9 0.4 2.0 1 1 1 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 PFH34883.1 - 0.00085 18.7 1.0 0.0014 18.0 0.2 1.9 2 1 0 2 2 2 1 KaiC AAA PF00004.29 PFH34883.1 - 0.0018 18.7 0.0 0.018 15.5 0.0 2.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HHH PF00633.23 PFH34883.1 - 0.042 13.7 0.1 0.091 12.7 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif PAXNEB PF05625.11 PFH34883.1 - 0.26 10.4 0.5 0.43 9.6 0.1 1.5 2 0 0 2 2 2 0 PAXNEB protein SpoU_methylase PF00588.19 PFH34884.1 - 6.5e-24 84.7 0.0 1.3e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family PhoLip_ATPase_N PF16209.5 PFH34885.1 - 1e-18 66.7 0.5 2.4e-18 65.6 0.5 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 PFH34885.1 - 0.0046 16.5 0.0 0.048 13.2 0.0 2.5 2 1 0 2 2 2 1 E1-E2 ATPase DUF3772 PF12607.8 PFH34885.1 - 0.082 12.7 4.6 1.5 8.7 0.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) PhoLip_ATPase_C PF16212.5 PFH34886.1 - 5.1e-58 196.8 22.8 6.2e-58 196.5 22.8 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 PFH34886.1 - 4.9e-09 36.8 0.0 7.9e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PFH34886.1 - 0.00043 20.1 0.1 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MttA_Hcf106 PF02416.16 PFH34886.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family DUF961 PF06125.11 PFH34887.1 - 0.066 13.6 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) Chorein_N PF12624.7 PFH34889.1 - 5.4e-20 71.6 0.1 1.1e-19 70.7 0.1 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 PFH34889.1 - 7.8e-17 61.6 0.0 1.5e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 PFH34889.1 - 1.8e-08 34.1 0.0 0.00032 20.2 0.0 2.8 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 PFH34889.1 - 0.00017 21.5 0.0 0.00049 20.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Mito_fiss_reg PF05308.11 PFH34890.1 - 1.9e-05 24.9 4.1 1.9e-05 24.9 4.1 2.9 3 0 0 3 3 3 1 Mitochondrial fission regulator zf-C2H2 PF00096.26 PFH34890.1 - 0.0014 18.9 2.1 0.0022 18.3 1.1 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type XPA_N PF01286.18 PFH34890.1 - 0.0056 16.7 1.3 0.0071 16.4 0.2 1.7 2 0 0 2 2 2 1 XPA protein N-terminal Guanylate_cyc PF00211.20 PFH34891.1 - 2e-08 34.1 0.1 3.5e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TMEM82 PF15816.5 PFH34891.1 - 0.15 11.0 1.3 0.19 10.7 0.0 1.7 3 0 0 3 3 3 0 Transmembrane protein 82 DUF167 PF02594.16 PFH34894.1 - 8.9e-26 89.8 0.2 1.5e-25 89.1 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Methyltransf_31 PF13847.6 PFH34895.1 - 4.9e-07 29.7 0.0 8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH34895.1 - 1.6e-06 28.8 0.0 2.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PFH34895.1 - 9.3e-06 25.6 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PFH34895.1 - 0.00023 21.7 0.0 0.00043 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH34895.1 - 0.00058 20.5 0.0 0.0011 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PFH34895.1 - 0.00075 18.9 0.0 0.001 18.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 PFH34895.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 PFH34895.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NTP_transf_3 PF12804.7 PFH34896.1 - 5.8e-15 56.0 0.5 1.3e-14 54.8 0.5 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 PFH34896.1 - 3.9e-08 33.2 0.0 8e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 PFH34896.1 - 8.3e-05 21.7 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 PFH34896.1 - 0.00058 18.1 0.5 0.34 9.0 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 PFH34896.1 - 0.0095 15.9 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Hexapep PF00132.24 PFH34896.1 - 0.015 15.0 0.6 0.32 10.8 0.0 2.6 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) SMC_N PF02463.19 PFH34897.1 - 1.3e-18 67.3 0.0 1.9e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PFH34897.1 - 3e-14 54.0 0.0 3e-14 54.0 0.0 4.6 2 2 0 3 3 3 1 AAA domain AAA_29 PF13555.6 PFH34897.1 - 0.00025 20.7 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 PFH34897.1 - 0.15 11.8 4.0 0.23 11.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Retrotrans_gag PF03732.17 PFH34897.1 - 0.65 10.3 4.0 0.53 10.6 0.1 2.9 3 1 1 4 4 4 0 Retrotransposon gag protein TBCC PF07986.12 PFH34898.1 - 1.5e-10 40.8 0.0 2.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 PFH34898.1 - 0.0062 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal AP2 PF00847.20 PFH34899.1 - 7.7e-09 35.7 7.6 1.6e-08 34.6 7.6 1.6 1 0 0 1 1 1 1 AP2 domain DRIM PF07539.12 PFH34900.1 - 6.3e-12 44.6 11.0 2.5e-06 26.1 0.5 7.3 6 2 0 6 6 6 4 Down-regulated in metastasis ANTH PF07651.16 PFH34900.1 - 0.068 12.2 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 ANTH domain HJURP_mid PF12346.8 PFH34900.1 - 0.15 12.6 5.1 0.77 10.2 5.1 2.3 1 0 0 1 1 1 0 Holliday junction recognition protein-associated repeat HEAT PF02985.22 PFH34900.1 - 0.17 12.2 5.1 66 4.2 0.4 5.6 4 0 0 4 4 4 0 HEAT repeat TB2_DP1_HVA22 PF03134.19 PFH34903.1 - 0.0072 16.2 5.2 0.012 15.6 5.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4400 PF14348.6 PFH34903.1 - 0.96 8.9 13.7 1.5 8.3 10.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Aminotran_5 PF00266.19 PFH34904.1 - 1.9e-117 392.3 0.0 1.3e-96 323.9 0.0 3.0 3 0 0 3 3 3 3 Aminotransferase class-V Peptidase_M3 PF01432.20 PFH34905.1 - 5.4e-26 91.9 0.1 2.1e-25 89.9 0.1 1.9 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.10 PFH34905.1 - 0.061 13.6 0.0 0.32 11.3 0.0 2.3 2 0 0 2 2 2 0 Oligopeptidase F SprT-like PF10263.9 PFH34905.1 - 0.1 12.4 2.4 1.4 8.8 1.0 2.4 2 0 0 2 2 2 0 SprT-like family Ribonucleas_3_3 PF14622.6 PFH34905.1 - 0.14 12.4 0.1 0.93 9.7 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease-III-like Ank_2 PF12796.7 PFH34906.1 - 2.9e-40 136.7 12.5 9.2e-12 45.4 0.1 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PFH34906.1 - 2.1e-25 86.0 3.8 0.0004 20.6 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 PFH34906.1 - 1.7e-23 82.7 3.0 8.6e-08 32.6 0.0 5.7 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 PFH34906.1 - 2.2e-23 81.6 3.6 5.5e-05 23.4 0.1 7.2 6 1 1 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 PFH34906.1 - 4.1e-20 71.6 7.2 5.7e-07 29.7 0.0 5.9 2 2 4 6 6 6 6 Ankyrin repeats (many copies) TPR_2 PF07719.17 PFH34906.1 - 3.5e-07 29.8 1.6 0.029 14.5 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PFH34906.1 - 0.00011 21.8 0.6 1.1 9.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PFH34906.1 - 0.00036 20.5 3.9 0.012 15.8 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 PFH34906.1 - 0.0011 18.6 1.4 0.016 14.9 0.2 2.9 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.6 PFH34906.1 - 0.0024 18.1 0.1 6.1 7.5 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF4810 PF16068.5 PFH34906.1 - 0.013 16.0 0.5 0.23 12.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) TPR_7 PF13176.6 PFH34906.1 - 0.016 15.2 1.7 0.91 9.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 PFH34906.1 - 0.083 13.0 1.5 3.3 7.9 0.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 PFH34906.1 - 0.086 13.1 4.6 1.3 9.3 2.8 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 PFH34906.1 - 0.7 10.9 13.2 9.3 7.4 0.4 5.2 2 1 2 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 PFH34906.1 - 1.8 9.2 7.3 0.56 10.9 2.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat UQ_con PF00179.26 PFH34907.1 - 1.7e-50 170.3 0.0 2.4e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PFH34907.1 - 0.0025 17.5 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 PFH34907.1 - 0.077 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain Effector_1 PF04518.12 PFH34909.1 - 0.016 14.3 5.5 0.023 13.8 3.2 1.9 2 0 0 2 2 2 0 Effector from type III secretion system HMMR_N PF15905.5 PFH34909.1 - 0.35 10.3 11.9 0.2 11.1 6.6 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 PFH34909.1 - 0.46 10.9 10.1 7.8 6.9 8.1 2.1 2 0 0 2 2 2 0 Fez1 DUF737 PF05300.11 PFH34909.1 - 0.55 10.5 16.5 1.6 9.1 16.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF737) XhlA PF10779.9 PFH34909.1 - 0.75 10.1 14.2 2.3 8.5 0.9 3.3 3 0 0 3 3 3 0 Haemolysin XhlA BLOC1_2 PF10046.9 PFH34909.1 - 0.79 10.1 9.5 7.7 6.9 0.7 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 PFH34909.1 - 0.81 10.2 10.1 3.9 8.0 4.6 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 OmpH PF03938.14 PFH34909.1 - 1.2 9.4 13.9 1.6 9.0 8.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.19 PFH34909.1 - 1.3 6.9 4.3 2.3 6.0 3.2 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CASP_C PF08172.12 PFH34909.1 - 1.3 8.3 8.1 1.5 8.1 3.2 2.1 2 0 0 2 2 2 0 CASP C terminal DUF4200 PF13863.6 PFH34909.1 - 1.5 9.2 16.1 4 7.9 4.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) CLZ PF16526.5 PFH34909.1 - 2 8.8 12.1 0.44 10.9 0.4 3.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prefoldin_2 PF01920.20 PFH34909.1 - 2.8 8.0 14.6 0.49 10.4 1.3 3.1 3 0 0 3 3 3 0 Prefoldin subunit DUF948 PF06103.11 PFH34909.1 - 3 8.1 6.6 4.6 7.6 1.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tweety PF04906.13 PFH34909.1 - 3.2 6.3 4.0 0.95 8.1 1.1 1.5 2 0 0 2 2 2 0 Tweety PI3K_P85_iSH2 PF16454.5 PFH34909.1 - 3.9 7.1 9.2 1.8 8.1 2.6 2.7 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DMPK_coil PF08826.10 PFH34909.1 - 4.1 7.6 17.9 3.1 8.0 0.7 3.7 3 1 0 3 3 3 0 DMPK coiled coil domain like Adaptin_binding PF10199.9 PFH34909.1 - 4.5 7.9 9.4 7.6 7.2 9.4 1.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Seryl_tRNA_N PF02403.22 PFH34909.1 - 4.9 7.4 15.6 6.9 7.0 9.3 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 PFH34909.1 - 5 6.1 10.7 21 4.1 8.3 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 PFH34909.1 - 6.3 6.1 14.7 6.5 6.0 8.1 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.6 PFH34909.1 - 9.2 6.8 11.8 9.5 6.7 6.9 2.7 2 1 0 2 2 2 0 Snapin/Pallidin SET PF00856.28 PFH34910.1 - 4.6e-09 36.9 0.7 1.5e-08 35.2 0.0 2.2 2 1 0 2 2 2 1 SET domain Peptidase_C2 PF00648.21 PFH34913.1 - 5.7e-33 114.2 0.0 4.3e-31 108.1 0.0 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Ank_2 PF12796.7 PFH34917.1 - 2.1e-27 95.5 0.8 1.1e-12 48.4 0.2 3.4 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PFH34917.1 - 3.3e-27 94.5 2.0 1.3e-09 38.4 0.0 5.8 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH34917.1 - 4.6e-22 75.7 1.2 0.00097 19.4 0.0 7.8 7 1 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 PFH34917.1 - 1.3e-19 69.7 7.1 0.00065 20.0 0.0 7.5 6 1 1 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 PFH34917.1 - 2.7e-18 65.8 8.6 0.00076 19.7 0.1 5.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) TPR_2 PF07719.17 PFH34917.1 - 1e-08 34.6 4.9 0.043 13.9 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 PFH34917.1 - 1.6e-08 34.0 3.9 0.015 15.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PFH34917.1 - 5.3e-07 29.2 1.0 0.012 15.3 0.2 2.7 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 PFH34917.1 - 8.9e-05 22.4 0.3 0.2 12.0 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 PFH34917.1 - 0.00058 19.7 3.6 0.25 11.3 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 PFH34917.1 - 0.0015 19.0 3.4 0.14 12.7 0.6 3.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 PFH34917.1 - 0.0077 16.5 7.4 0.63 10.4 1.5 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 PFH34917.1 - 0.026 14.9 1.2 10 6.7 0.0 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 PFH34917.1 - 0.058 13.4 5.5 3.1 8.0 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3807 PF12720.7 PFH34917.1 - 0.2 11.9 1.8 0.35 11.1 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) TPR_9 PF13371.6 PFH34917.1 - 0.59 10.3 13.5 1 9.6 0.8 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 PFH34917.1 - 1.1 9.9 25.2 0.093 13.4 2.6 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 PFH34917.1 - 2.5 9.1 22.0 0.3 12.0 1.2 5.3 4 2 1 5 5 4 0 Tetratricopeptide repeat Ribosomal_S15 PF00312.22 PFH34918.1 - 6.9e-21 74.2 1.0 1.1e-20 73.6 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 VHS PF00790.19 PFH34919.1 - 1.7e-05 24.7 0.5 0.19 11.6 0.0 2.2 1 1 1 2 2 2 2 VHS domain Peptidase_C78 PF07910.13 PFH34920.1 - 5.7e-42 143.6 0.0 7.6e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 ribosomal_L24 PF17136.4 PFH34921.1 - 7.1e-12 45.5 0.1 1.2e-11 44.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 PFH34921.1 - 0.00028 20.7 0.7 0.00028 20.7 0.7 1.8 2 0 0 2 2 2 1 KOW motif IMCp PF12314.8 PFH34922.1 - 1.5e-11 44.4 55.1 3.2e-09 36.9 34.5 3.3 1 1 1 3 3 3 3 Inner membrane complex protein Helicase_C_2 PF13307.6 PFH34923.1 - 1.8e-31 109.6 0.0 1.1e-29 103.8 0.0 2.8 2 1 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 PFH34923.1 - 7.1e-28 97.4 0.0 1.4e-26 93.2 0.0 2.2 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.15 PFH34923.1 - 4.5e-07 30.0 0.0 0.00092 19.2 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PFH34923.1 - 0.047 14.0 0.1 2.8 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PFH34923.1 - 0.058 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 PFH34923.1 - 1 9.1 5.8 19 4.9 5.8 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase HTH_Tnp_Tc5 PF03221.16 PFH34924.1 - 1.1e-07 31.8 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.20 PFH34924.1 - 1.9e-05 24.9 0.2 6.6e-05 23.2 0.2 1.9 1 0 0 1 1 1 1 Transposase BrkDBD PF09607.10 PFH34924.1 - 2.7e-05 23.8 0.1 5.1e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Brinker DNA-binding domain Nnf1 PF03980.14 PFH34924.1 - 0.027 14.8 0.2 0.065 13.6 0.2 1.6 1 0 0 1 1 1 0 Nnf1 HTH_29 PF13551.6 PFH34924.1 - 0.028 14.4 0.2 0.028 14.4 0.2 2.6 2 0 0 2 2 2 0 Winged helix-turn helix Acatn PF13000.7 PFH34925.1 - 2.1e-110 369.9 0.1 8.1e-69 232.6 0.0 3.4 2 1 0 2 2 2 2 Acetyl-coenzyme A transporter 1 Med21 PF11221.8 PFH34926.1 - 8.2e-14 52.1 2.6 1.1e-13 51.7 2.6 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Not3 PF04065.15 PFH34926.1 - 0.015 14.7 0.3 0.019 14.4 0.3 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Nbl1_Borealin_N PF10444.9 PFH34926.1 - 0.33 10.6 3.8 1.2 8.9 0.1 2.8 2 1 1 3 3 3 0 Nbl1 / Borealin N terminal APG6_N PF17675.1 PFH34926.1 - 1.1 9.8 7.7 2.3 8.8 7.7 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region SWIRM-assoc_2 PF16496.5 PFH34927.1 - 0.11 11.3 6.3 0.14 11.0 6.3 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Ubiq_cyt_C_chap PF03981.12 PFH34928.1 - 1.3e-11 44.8 0.1 1.9e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone bMG10 PF17973.1 PFH34929.1 - 3.7e-08 33.6 0.0 1.4e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain MG2 PF01835.19 PFH34929.1 - 0.012 16.0 0.0 0.39 11.2 0.0 3.0 2 0 0 2 2 2 0 MG2 domain TFIIA PF03153.13 PFH34931.1 - 0.85 9.5 42.1 0.84 9.6 27.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF5576 PF17739.1 PFH34931.1 - 5.2 7.2 7.5 1.1 9.3 3.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5576) SF3a60_bindingd PF12108.8 PFH34932.1 - 0.095 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain SF3a60_bindingd PF12108.8 PFH34933.1 - 0.095 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain SF3a60_bindingd PF12108.8 PFH34934.1 - 0.095 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain SF3a60_bindingd PF12108.8 PFH34935.1 - 0.095 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain SF3a60_bindingd PF12108.8 PFH34936.1 - 0.095 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Kelch_1 PF01344.25 PFH34937.1 - 8.9e-49 162.8 15.9 1.1e-12 47.3 0.1 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 PFH34937.1 - 2.8e-39 132.1 12.9 2.1e-10 40.5 0.0 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_3 PF13415.6 PFH34937.1 - 1.1e-37 127.6 19.9 2.5e-11 43.6 0.1 8.6 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_4 PF13418.6 PFH34937.1 - 2e-37 127.0 8.3 8.3e-09 35.3 0.0 6.7 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 PFH34937.1 - 5.3e-34 114.9 20.8 3.1e-08 33.3 0.0 7.7 9 0 0 9 9 9 6 Kelch motif Kelch_5 PF13854.6 PFH34937.1 - 1.6e-29 101.3 18.1 4e-08 33.1 0.1 6.6 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 PFH34937.1 - 8.6e-20 71.0 0.5 9.5e-19 67.7 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain GYF PF02213.16 PFH34938.1 - 4.4e-11 42.3 1.6 9.1e-11 41.3 1.6 1.5 1 0 0 1 1 1 1 GYF domain MOZART1 PF12554.8 PFH34939.1 - 0.018 14.9 0.1 0.073 12.9 0.0 1.8 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated VTC PF09359.10 PFH34940.1 - 1.1e-18 67.6 0.0 7.3e-18 64.9 0.0 2.0 1 1 0 1 1 1 1 VTC domain SPX PF03105.19 PFH34940.1 - 4.5e-14 53.2 2.7 4.3e-12 46.6 0.1 3.8 3 1 1 4 4 4 2 SPX domain DUF202 PF02656.15 PFH34940.1 - 6.5e-14 52.1 3.0 6.5e-14 52.1 3.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Prp18 PF02840.15 PFH34941.1 - 1.2e-59 200.5 0.6 1.2e-59 200.5 0.6 2.5 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 PFH34941.1 - 6.9e-12 44.7 0.0 1.9e-11 43.3 0.0 1.9 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like HD_2 PF12917.7 PFH34941.1 - 0.011 15.5 2.5 2.5 7.8 0.4 2.4 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme DUF2300 PF10062.9 PFH34941.1 - 0.76 9.9 7.3 0.29 11.2 0.7 2.4 2 0 0 2 2 2 0 Predicted secreted protein (DUF2300) SPOUT_MTase PF02590.17 PFH34942.1 - 0.0032 17.4 0.8 0.024 14.6 0.0 2.6 3 1 0 3 3 3 1 Predicted SPOUT methyltransferase DUF5333 PF17267.2 PFH34942.1 - 0.042 14.0 0.3 0.084 13.1 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5333) IFT20 PF14931.6 PFH34942.1 - 0.16 12.1 0.8 1.5 9.0 1.0 2.2 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Pkinase PF00069.25 PFH34944.1 - 5.2e-76 255.5 0.0 6.6e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34944.1 - 1.4e-36 126.1 0.0 1.9e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 PFH34944.1 - 3.5e-15 56.4 0.0 5.6e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 PFH34944.1 - 2.7e-08 33.5 0.0 1.3e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PFH34944.1 - 3.7e-05 22.7 0.0 5.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PFH34944.1 - 0.00016 21.1 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PFH34944.1 - 0.0046 16.6 0.2 0.0079 15.8 0.2 1.3 1 0 0 1 1 1 1 RIO1 family PH_8 PF15409.6 PFH34944.1 - 0.0075 16.5 0.5 0.024 14.9 0.5 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain Pox_ser-thr_kin PF05445.11 PFH34944.1 - 0.036 13.0 0.1 0.054 12.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 PFH34944.1 - 0.05 13.5 0.1 0.52 10.2 0.1 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 PFH34944.1 - 0.051 13.2 0.1 0.38 10.4 0.0 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PH_11 PF15413.6 PFH34944.1 - 0.068 13.6 0.9 0.51 10.8 0.4 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain EF-hand_1 PF00036.32 PFH34945.1 - 2.3e-09 36.1 1.5 0.00055 19.3 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 PFH34945.1 - 2.4e-08 33.2 0.1 0.00027 20.6 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PFH34945.1 - 6.5e-07 28.6 0.9 0.0011 18.4 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PFH34945.1 - 2.1e-06 28.1 2.6 2.3e-05 24.8 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 PFH34945.1 - 1.3e-05 24.9 2.1 0.11 12.4 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair CRT-like PF08627.10 PFH34947.1 - 7.7e-16 58.0 3.9 3.1e-10 39.5 0.0 4.1 4 0 0 4 4 4 4 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 PFH34947.1 - 0.042 13.0 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-sugar transporter UPF0086 PF01868.16 PFH34948.1 - 2.9e-15 55.9 0.2 4.6e-15 55.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 DAP10 PF07213.11 PFH34948.1 - 0.08 12.9 0.3 0.21 11.6 0.3 1.6 1 0 0 1 1 1 0 DAP10 membrane protein Lactamase_B_6 PF16661.5 PFH34949.1 - 0.0012 18.3 0.3 0.075 12.5 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 PFH34949.1 - 0.0068 16.7 0.0 0.037 14.3 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain PI3_PI4_kinase PF00454.27 PFH34950.1 - 4.4e-35 121.7 0.1 1.4e-30 106.9 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Mito_carr PF00153.27 PFH34951.1 - 2.7e-49 165.1 2.8 4.1e-17 61.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4199 PF13858.6 PFH34951.1 - 0.11 12.9 4.1 13 6.2 0.7 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4199) zf-H2C2_2 PF13465.6 PFH34952.1 - 1.5 9.4 4.2 22 5.7 1.5 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Sec7 PF01369.20 PFH34953.1 - 6.5e-62 208.5 0.0 1.2e-61 207.6 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain DUF1981 PF09324.10 PFH34953.1 - 3.4e-21 74.9 2.0 1.6e-20 72.7 0.9 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 PFH34953.1 - 1e-18 67.7 0.0 1e-18 67.7 0.0 4.0 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 PFH34953.1 - 9.8e-12 44.9 8.7 1.8e-07 31.0 0.1 4.8 6 0 0 6 6 6 2 Dimerisation and cyclophilin-binding domain of Mon2 Nterm_IS4 PF13006.7 PFH34953.1 - 0.12 12.6 0.2 26 5.1 0.2 2.9 2 0 0 2 2 2 0 Insertion element 4 transposase N-terminal zf-HIT PF04438.16 PFH34953.1 - 1.6 8.7 4.0 3.3 7.7 4.0 1.6 1 0 0 1 1 1 0 HIT zinc finger PBP PF01161.20 PFH34955.1 - 2e-14 54.0 0.0 2.8e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF2706 PF10913.8 PFH34955.1 - 0.15 11.9 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) Ank_2 PF12796.7 PFH34956.1 - 1.3e-23 83.4 0.1 2.1e-16 60.3 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PFH34956.1 - 9.9e-23 79.9 0.0 4.2e-08 33.3 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PFH34956.1 - 8.6e-22 76.6 0.1 2.9e-06 27.5 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 PFH34956.1 - 1.7e-19 69.9 0.5 4.7e-08 33.4 0.1 4.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH34956.1 - 3.6e-17 60.7 0.0 2.9e-05 24.1 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat PDEase_I PF00233.19 PFH34957.1 - 2.5e-66 223.8 0.1 4e-66 223.1 0.1 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HATPase_c PF02518.26 PFH34957.1 - 0.00031 21.2 0.0 0.00055 20.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Amidase_5 PF05382.13 PFH34957.1 - 0.061 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase BCIP PF13862.6 PFH34958.1 - 3.5e-39 134.7 0.0 5.5e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Ribosomal_L15e PF00827.17 PFH34959.1 - 1.5e-89 298.8 8.8 1.9e-89 298.5 8.8 1.1 1 0 0 1 1 1 1 Ribosomal L15 Hepatitis_core PF00906.20 PFH34959.1 - 1.7 8.2 7.9 3.9 7.0 0.3 2.1 2 0 0 2 2 2 0 Hepatitis core antigen CytochromB561_N PF09786.9 PFH34962.1 - 0.067 12.2 0.8 0.077 12.0 0.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Pkinase PF00069.25 PFH34964.1 - 1.6e-61 208.0 0.0 2.6e-61 207.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH34964.1 - 4.4e-34 117.9 0.0 5.7e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH34964.1 - 6.6e-08 32.2 0.0 1.2e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 PFH34964.1 - 0.031 13.8 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 PFH34964.1 - 0.051 13.5 0.0 0.73 9.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PFH34964.1 - 0.074 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 PFH34964.1 - 0.16 10.8 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain TTL PF03133.15 PFH34965.1 - 1.9e-76 257.0 0.0 1.8e-53 181.6 0.1 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PFH34965.1 - 1.5e-07 30.9 0.1 0.00015 21.1 0.0 3.2 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PFH34965.1 - 0.0002 20.7 0.0 0.036 13.3 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 PFH34965.1 - 0.17 11.9 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain PX PF00787.24 PFH34966.1 - 1.7e-14 53.8 0.0 2.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 PX domain WD40 PF00400.32 PFH34966.1 - 2.6e-07 31.2 1.9 0.17 12.8 0.6 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH34966.1 - 0.0043 17.3 0.0 9.3 6.6 0.0 3.9 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RICTOR_M PF14666.6 PFH34967.1 - 1.5e-06 27.9 0.0 3.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.6 PFH34967.1 - 0.0045 16.0 0.7 0.16 11.0 0.1 3.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.6 PFH34967.1 - 0.014 15.6 0.1 8.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 F-box PF00646.33 PFH34968.1 - 0.3 11.0 6.5 0.24 11.3 3.9 2.3 2 1 0 2 2 2 0 F-box domain S1-P1_nuclease PF02265.16 PFH34970.1 - 5.9e-24 85.3 0.0 9.5e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 S1/P1 Nuclease FKBP_C PF00254.28 PFH34971.1 - 6.9e-22 77.6 0.0 1.2e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GTP_EFTU PF00009.27 PFH34972.1 - 2e-24 86.3 0.0 4e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PFH34972.1 - 4.6e-11 42.8 0.0 1.1e-05 25.5 0.0 2.5 2 0 0 2 2 2 2 Translation-initiation factor 2 MMR_HSR1 PF01926.23 PFH34972.1 - 8.3e-06 25.9 0.0 4.2e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF4685 PF15737.5 PFH34973.1 - 0.0051 17.2 1.0 0.0051 17.2 1.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4685) Crust_neuro_H PF03858.13 PFH34973.1 - 0.73 10.7 4.8 1.6 9.6 0.6 3.6 3 0 0 3 3 3 0 Crustacean neurohormone H NIF PF03031.18 PFH34974.1 - 2.8e-14 53.2 0.0 2.7e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 PFH34974.1 - 0.0013 18.6 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain ADD_DNMT3 PF17980.1 PFH34974.1 - 0.036 14.1 1.0 0.081 12.9 1.0 1.5 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 Biotin_lipoyl_2 PF13533.6 PFH34974.1 - 0.062 13.1 0.0 2.5 8.0 0.0 2.7 3 0 0 3 3 3 0 Biotin-lipoyl like Parathyroid PF01279.17 PFH34975.1 - 0.32 11.7 3.1 2.1 9.0 0.1 2.6 2 0 0 2 2 2 0 Parathyroid hormone family RBFA PF02033.18 PFH34976.1 - 1.6e-13 51.0 0.0 2.8e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Ribosome-binding factor A ACT PF01842.25 PFH34976.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 ACT domain DUF1129 PF06570.11 PFH34977.1 - 0.067 12.7 0.6 0.091 12.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) NFACT-R_1 PF05670.13 PFH34978.1 - 1.1e-40 138.7 0.0 1.6e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain Abhydrolase_2 PF02230.16 PFH34979.1 - 8.7e-38 130.3 0.0 1e-35 123.5 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 PFH34979.1 - 0.00011 22.9 10.3 0.0002 22.0 8.4 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 PFH34979.1 - 0.00017 21.2 0.0 0.00038 20.0 0.0 1.6 2 0 0 2 2 2 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 PFH34979.1 - 0.00046 19.5 0.1 0.047 12.9 0.1 3.0 2 1 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PFH34979.1 - 0.001 18.8 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 PFH34979.1 - 0.002 17.8 0.0 0.0046 16.6 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 PFH34979.1 - 0.047 13.5 0.0 0.091 12.6 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 PFH34979.1 - 0.054 13.0 0.1 0.26 10.8 0.1 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Lipase_3 PF01764.25 PFH34979.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 PFH34979.1 - 0.16 11.6 0.0 0.44 10.1 0.0 1.6 2 0 0 2 2 2 0 Putative esterase AXE1 PF05448.12 PFH34979.1 - 0.26 9.9 0.0 0.39 9.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Rick_17kDa_Anti PF05433.15 PFH34981.1 - 0.14 12.0 2.9 0.16 11.8 0.3 2.2 2 0 0 2 2 2 0 Glycine zipper 2TM domain GTP_EFTU PF00009.27 PFH34982.1 - 2.7e-30 105.4 0.0 1.9e-29 102.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PFH34982.1 - 1.2e-12 47.9 0.0 2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 PFH34982.1 - 5.3e-08 33.0 0.0 9.6e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PFH34982.1 - 0.0033 17.5 0.1 0.014 15.5 0.1 1.9 1 1 0 2 2 2 1 Dynamin family TniB PF05621.11 PFH34982.1 - 0.15 11.5 0.0 6.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 PFH34982.1 - 0.28 10.7 0.1 4.3 6.8 0.1 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B zf-MYND PF01753.18 PFH34984.1 - 7.9e-09 35.5 17.7 1.7e-08 34.4 17.7 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 PFH34984.1 - 2 8.4 9.2 5.1 7.1 9.2 1.7 1 0 0 1 1 1 0 HIT zinc finger AAA PF00004.29 PFH34985.1 - 2.4e-42 144.5 0.0 4.2e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PFH34985.1 - 4e-12 45.7 0.4 8.7e-12 44.7 0.4 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 PFH34985.1 - 1.9e-08 34.1 0.1 3.8e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 PFH34985.1 - 1.3e-07 32.1 0.2 0.00014 22.3 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 PFH34985.1 - 3.1e-07 30.7 0.0 9.6e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PFH34985.1 - 1.2e-06 28.6 0.0 6.3e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PFH34985.1 - 5.4e-06 26.2 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PFH34985.1 - 0.00013 22.2 0.5 0.015 15.5 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PFH34985.1 - 0.00024 21.6 0.0 0.0023 18.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PFH34985.1 - 0.00069 19.2 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 PFH34985.1 - 0.001 18.8 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Prot_ATP_OB_N PF17758.1 PFH34985.1 - 0.0012 18.4 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain TIP49 PF06068.13 PFH34985.1 - 0.0016 17.7 0.2 0.0032 16.7 0.0 1.5 2 0 0 2 2 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 PFH34985.1 - 0.0022 18.4 0.0 0.0045 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 PFH34985.1 - 0.0035 17.1 0.0 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 PFH34985.1 - 0.0042 16.5 0.1 0.0078 15.6 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 PFH34985.1 - 0.0055 16.4 0.0 0.018 14.7 0.0 1.9 2 1 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 PFH34985.1 - 0.0056 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 PFH34985.1 - 0.0057 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 PFH34985.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4200 PF13863.6 PFH34985.1 - 0.0074 16.7 0.5 0.02 15.3 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_14 PF13173.6 PFH34985.1 - 0.012 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PFH34985.1 - 0.014 15.7 0.0 0.036 14.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 PFH34985.1 - 0.014 14.9 0.1 0.03 13.8 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 PFH34985.1 - 0.022 13.8 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 PFH34985.1 - 0.024 14.8 0.0 0.062 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 PFH34985.1 - 0.03 14.1 0.1 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 PFH34985.1 - 0.031 13.6 0.0 0.081 12.3 0.0 1.7 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 PFH34985.1 - 0.068 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 PFH34985.1 - 0.071 12.7 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PFH34985.1 - 0.098 12.6 0.1 0.42 10.5 0.1 2.2 1 1 0 1 1 1 0 NACHT domain V-ATPase_G PF03179.15 PFH34986.1 - 0.00021 21.8 9.2 0.00057 20.4 9.2 1.7 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit HrpE PF06188.12 PFH34986.1 - 0.011 15.7 4.7 0.021 14.7 4.7 1.4 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF3552 PF12072.8 PFH34986.1 - 0.04 13.3 10.2 0.078 12.4 10.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1117 PF06547.12 PFH34986.1 - 0.38 11.3 3.5 0.16 12.5 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) ATP-synt_B PF00430.18 PFH34986.1 - 0.75 9.9 13.4 1.6 8.8 13.4 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Caldesmon PF02029.15 PFH34986.1 - 1.4 7.6 15.9 0.16 10.7 11.4 1.5 2 0 0 2 2 2 0 Caldesmon JAB PF01398.21 PFH34987.1 - 2.4e-14 53.3 0.1 4.4e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 PFH34987.1 - 7e-10 39.3 0.0 1.1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function COX15-CtaA PF02628.15 PFH34988.1 - 6.4e-86 288.4 9.2 1.1e-85 287.6 9.2 1.3 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein Metallophos PF00149.28 PFH34990.1 - 4e-08 34.0 1.4 7.8e-08 33.1 1.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UPF0242 PF06785.11 PFH34990.1 - 1.7 8.7 30.9 0.01 15.9 7.0 4.3 4 2 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 PFH34990.1 - 3.2 7.8 8.1 4.5 7.3 2.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Metallophos PF00149.28 PFH34991.1 - 8e-08 33.0 0.6 7.5e-07 29.8 0.3 2.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase START PF01852.19 PFH34993.1 - 6e-06 25.8 0.1 1.3e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 START domain DNMT1-RFD PF12047.8 PFH34994.1 - 5.9e-08 32.9 3.4 1.1e-07 32.0 0.3 2.7 3 0 0 3 3 3 1 Cytosine specific DNA methyltransferase replication foci domain WSD PF15613.6 PFH34995.1 - 7.7e-06 26.3 5.3 0.0044 17.5 0.0 3.9 4 0 0 4 4 4 2 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Auxin_resp PF06507.13 PFH34995.1 - 1.6e-05 25.0 0.1 0.00011 22.4 0.0 2.1 2 0 0 2 2 2 1 Auxin response factor Tmemb_14 PF03647.13 PFH34996.1 - 7.7e-12 45.8 11.2 8.9e-12 45.6 11.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C ANAPC4_WD40 PF12894.7 PFH34997.1 - 0.0022 18.2 0.0 0.31 11.4 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PFH34997.1 - 0.026 15.4 13.9 6.3 7.8 0.0 7.9 9 0 0 9 9 9 0 WD domain, G-beta repeat Dus PF01207.17 PFH34998.1 - 2.2e-46 158.4 0.0 3.4e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Frankia_peptide PF14407.6 PFH34998.1 - 0.03 14.3 0.2 0.45 10.5 0.0 2.4 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. B-block_TFIIIC PF04182.12 PFH34999.1 - 8.4e-08 32.3 0.0 2.7e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_5 PF01022.20 PFH34999.1 - 0.00033 20.4 0.2 0.0024 17.7 0.0 2.6 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family FHA PF00498.26 PFH35004.1 - 3.6e-15 56.1 0.0 6.3e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain Rotamase PF00639.21 PFH35004.1 - 6.3e-13 49.5 0.1 3.6e-12 47.1 0.0 2.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Yop-YscD_cpl PF16697.5 PFH35004.1 - 5.4e-05 23.4 0.0 0.00015 22.0 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Rotamase_2 PF13145.6 PFH35004.1 - 0.0067 17.3 4.6 0.06 14.2 0.0 3.1 3 0 0 3 3 3 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 PFH35004.1 - 0.014 15.9 0.0 0.071 13.7 0.0 2.2 1 1 0 1 1 1 0 PPIC-type PPIASE domain MitMem_reg PF13012.6 PFH35006.1 - 1.4e-05 25.5 0.0 5.2e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function SF3A2 PF16835.5 PFH35007.1 - 1.1e-29 102.6 0.3 1.7e-29 102.0 0.3 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 PFH35007.1 - 1.5e-05 25.2 0.4 2.6e-05 24.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 PFH35007.1 - 7.9e-05 22.6 0.5 0.00016 21.6 0.5 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PUA PF01472.20 PFH35008.1 - 0.021 14.8 0.3 5.9 6.9 0.0 2.5 2 0 0 2 2 2 0 PUA domain Bac_DNA_binding PF00216.21 PFH35010.1 - 1.9e-26 92.1 0.2 2.8e-26 91.6 0.2 1.3 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 PFH35010.1 - 9.7e-06 25.7 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_1 PF14908.6 PFH35010.1 - 0.00026 21.1 0.0 0.0006 19.9 0.0 1.6 1 1 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_bac_2 PF18175.1 PFH35010.1 - 0.00091 19.0 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 PFH35010.1 - 0.0098 16.0 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_bac_1 PF18174.1 PFH35010.1 - 0.13 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 RPN6_N PF18055.1 PFH35011.1 - 3.3e-26 91.9 2.1 1e-25 90.4 0.0 2.6 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 PFH35011.1 - 2.2e-18 66.7 0.2 2.2e-18 66.7 0.2 2.4 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 PFH35011.1 - 2e-05 24.2 0.2 2e-05 24.2 0.2 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 PFH35011.1 - 0.0008 19.6 0.2 0.0008 19.6 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PFH35011.1 - 0.0068 16.4 1.9 25 5.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat STAG PF08514.11 PFH35011.1 - 0.11 12.4 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 STAG domain TPR_6 PF13174.6 PFH35011.1 - 0.5 11.1 4.1 18 6.2 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat 14-3-3 PF00244.20 PFH35012.1 - 3.6e-22 79.0 1.0 4.9e-22 78.5 1.0 1.2 1 0 0 1 1 1 1 14-3-3 protein M16C_assoc PF08367.11 PFH35013.1 - 4.9e-52 176.5 0.0 7.8e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 PFH35013.1 - 8.5e-22 78.0 0.1 6.9e-19 68.6 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PFH35013.1 - 0.00015 21.8 0.0 0.0012 18.9 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) MRP-S31 PF15433.6 PFH35015.1 - 1.5 8.4 16.1 2.6 7.7 16.1 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Macoilin PF09726.9 PFH35015.1 - 6.7 5.1 26.5 12 4.3 26.5 1.3 1 0 0 1 1 1 0 Macoilin family UcrQ PF02939.16 PFH35017.1 - 0.021 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 UcrQ family NinD PF17466.2 PFH35017.1 - 0.077 13.1 1.7 5.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function zf-Tim10_DDP PF02953.15 PFH35021.1 - 2.3e-11 43.1 3.4 3.2e-11 42.7 3.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger T3SS_HrpK1 PF16937.5 PFH35021.1 - 0.00046 19.9 0.1 0.00052 19.8 0.1 1.0 1 0 0 1 1 1 1 Type III secretion system translocator protein, HrpF DUF842 PF05811.13 PFH35021.1 - 0.026 14.2 3.7 0.034 13.8 3.7 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) MRP-S25 PF13741.6 PFH35022.1 - 0.094 12.3 5.0 0.61 9.6 0.5 3.0 2 1 0 3 3 3 0 Mitochondrial ribosomal protein S25 Pro_isomerase PF00160.21 PFH35023.1 - 4.2e-24 85.6 0.0 4.2e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 PFH35023.1 - 5.2e-14 51.8 0.0 8.9e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Memo PF01875.17 PFH35024.1 - 1.8e-75 253.6 0.0 2.2e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Tim44 PF04280.15 PFH35025.1 - 5.9e-22 78.4 0.0 1.1e-20 74.3 0.0 2.5 1 1 0 1 1 1 1 Tim44-like domain ApoLp-III PF07464.11 PFH35025.1 - 0.31 11.1 12.2 0.55 10.3 11.3 1.8 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Vps54_N PF10475.9 PFH35026.1 - 0.00066 19.1 4.7 0.00066 19.1 4.7 1.8 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 PFH35026.1 - 6.1 6.9 6.3 28 4.8 6.3 2.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Pkinase PF00069.25 PFH35027.1 - 6.3e-13 48.7 0.0 8.3e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PFH35027.1 - 2.5e-10 40.2 0.0 4.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH35027.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.22 PFH35027.1 - 0.15 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family EF-hand_4 PF12763.7 PFH35028.1 - 5.1e-09 36.0 0.0 3.3e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 PFH35028.1 - 0.021 15.3 0.0 11 6.5 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 PFH35028.1 - 0.026 14.0 0.0 4.1 7.2 0.0 3.0 3 0 0 3 3 3 0 EF hand DUF1635 PF07795.11 PFH35028.1 - 7.9 6.3 17.6 0.15 11.9 10.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Glycos_transf_1 PF00534.20 PFH35029.1 - 7.3e-26 90.7 0.0 1.3e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PFH35029.1 - 2.4e-16 60.4 0.0 1.2e-15 58.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 PFH35029.1 - 2.6e-06 27.7 0.1 6.1e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PFH35029.1 - 0.0002 21.4 0.1 0.0011 19.1 0.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 E1-E2_ATPase PF00122.20 PFH35030.1 - 5.6e-05 22.7 0.1 0.0023 17.5 0.0 2.5 2 0 0 2 2 2 2 E1-E2 ATPase CopD PF05425.13 PFH35031.1 - 0.18 12.2 12.8 0.16 12.4 2.0 3.7 3 0 0 3 3 3 0 Copper resistance protein D Cation_ATPase_C PF00689.21 PFH35031.1 - 0.47 10.1 21.1 1.3 8.8 4.2 3.6 3 1 0 3 3 3 0 Cation transporting ATPase, C-terminus DUF4381 PF14316.6 PFH35031.1 - 0.57 10.4 5.1 0.71 10.1 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Wzy_C PF04932.15 PFH35031.1 - 0.6 9.7 6.6 11 5.6 0.1 3.3 3 1 0 3 3 3 0 O-Antigen ligase SNARE PF05739.19 PFH35031.1 - 6.1 6.9 10.6 2.4 8.2 6.2 2.5 2 0 0 2 2 2 0 SNARE domain DNA_methylase PF00145.17 PFH35032.1 - 1e-20 74.4 0.0 1.2e-11 44.6 0.0 3.1 3 0 0 3 3 3 3 C-5 cytosine-specific DNA methylase EB1 PF03271.17 PFH35033.1 - 2.5e-10 40.4 0.0 7.4e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 EB1-like C-terminal motif AKNA PF12443.8 PFH35033.1 - 0.014 16.0 0.0 0.014 16.0 0.0 2.3 2 1 1 3 3 3 0 AT-hook-containing transcription factor NEMO PF11577.8 PFH35033.1 - 0.15 12.1 1.6 0.33 11.0 1.6 1.4 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Macoilin PF09726.9 PFH35033.1 - 0.16 10.5 2.0 0.24 9.9 2.0 1.2 1 0 0 1 1 1 0 Macoilin family MAD PF05557.13 PFH35033.1 - 0.21 9.9 3.0 2.2 6.5 0.2 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF241 PF03087.14 PFH35034.1 - 0.011 15.6 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function DUF883 PF05957.13 PFH35034.1 - 0.085 13.5 1.3 0.22 12.2 1.3 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) TRAPPC10 PF12584.8 PFH35035.1 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_14 PF13428.6 PFH35035.1 - 1.4 10.0 4.0 8.9 7.4 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L34e PF01199.18 PFH35036.1 - 5.6e-39 132.4 5.1 5.6e-39 132.4 5.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L34e zf-3CxxC_2 PF17180.4 PFH35036.1 - 0.056 14.2 4.0 0.056 14.2 4.0 2.1 1 1 1 2 2 2 0 Zinc-binding domain FhuF_C PF11575.8 PFH35036.1 - 0.27 11.2 4.1 9 6.3 0.4 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain GN3L_Grn1 PF08701.11 PFH35036.1 - 0.28 11.3 0.1 0.28 11.3 0.1 2.2 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase Cytochrome_C7 PF14522.6 PFH35036.1 - 4.4 7.4 9.2 0.34 10.9 1.2 2.2 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c DUF5474 PF17568.2 PFH35037.1 - 0.0023 18.0 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5474) MRP-S33 PF08293.11 PFH35037.1 - 0.056 13.7 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 Aa_trans PF01490.18 PFH35038.1 - 1.1e-44 152.8 26.8 1.3e-44 152.6 26.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2613 PF11021.8 PFH35038.1 - 0.13 12.3 3.8 0.6 10.3 3.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Aa_trans PF01490.18 PFH35039.1 - 1.4e-55 188.7 30.0 1.7e-55 188.4 30.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 PFH35040.1 - 3.3e-54 184.2 27.4 4.2e-54 183.8 27.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Phage_holin_3_3 PF16083.5 PFH35040.1 - 0.34 11.1 0.0 0.34 11.1 0.0 3.8 5 0 0 5 5 5 0 LydA holin phage, holin superfamily III Med26 PF08711.11 PFH35041.1 - 2.3e-05 24.3 0.1 5.6e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain NARP1 PF12569.8 PFH35041.1 - 4.5 6.1 10.5 1.4 7.7 7.4 1.7 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DCP2 PF05026.13 PFH35042.1 - 1.8e-20 73.0 1.6 2.9e-20 72.4 1.6 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 PFH35042.1 - 1.2e-08 35.1 0.1 2.7e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain LsmAD PF06741.13 PFH35042.1 - 0.11 13.1 0.0 0.11 13.1 0.0 2.3 2 0 0 2 2 2 0 LsmAD domain WD40 PF00400.32 PFH35043.1 - 3.8e-14 52.8 13.8 0.0055 17.5 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH35043.1 - 1.4e-06 28.5 0.0 0.14 12.5 0.0 3.4 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 PFH35043.1 - 0.037 13.7 0.0 6.3 6.4 0.0 2.5 2 0 0 2 2 2 0 TUP1-like enhancer of split Aa_trans PF01490.18 PFH35044.1 - 2.2e-46 158.4 22.4 2.6e-46 158.1 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein LYTB PF02401.18 PFH35045.1 - 5e-83 278.4 0.1 6.6e-83 278.0 0.1 1.1 1 0 0 1 1 1 1 LytB protein CoA_binding_2 PF13380.6 PFH35045.1 - 0.0063 17.0 2.9 0.55 10.8 0.1 3.2 2 1 1 3 3 3 2 CoA binding domain 3HCDH_RFF PF18321.1 PFH35045.1 - 0.028 14.9 2.6 0.57 10.7 0.0 3.5 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain TYW3 PF02676.14 PFH35047.1 - 4e-24 85.2 0.0 1.5e-23 83.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase TYW3 SET PF00856.28 PFH35049.1 - 9.4e-07 29.4 0.0 1.9e-05 25.2 0.0 2.6 1 1 0 1 1 1 1 SET domain Peptidase_S15 PF02129.18 PFH35050.1 - 2.4e-33 115.9 0.1 2.3e-32 112.7 0.1 2.6 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 PFH35050.1 - 2.7e-13 50.4 0.2 3.1e-10 40.4 0.0 2.5 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 PFH35050.1 - 0.0065 15.8 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PFH35050.1 - 0.018 14.5 2.5 0.039 13.4 2.5 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 PFH35050.1 - 0.032 13.9 0.2 0.084 12.5 0.2 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ribosomal_L3 PF00297.22 PFH35051.1 - 3.8e-176 585.5 3.4 4.4e-176 585.3 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Patched PF02460.18 PFH35052.1 - 2.6e-08 32.5 0.2 0.00096 17.4 1.2 3.4 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 PFH35052.1 - 0.18 11.6 14.2 0.68 9.8 3.2 3.5 3 0 0 3 3 3 0 Sterol-sensing domain of SREBP cleavage-activation Spc29 PF17082.5 PFH35053.1 - 0.053 13.4 0.7 0.094 12.5 0.7 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 JIP_LZII PF16471.5 PFH35053.1 - 0.9 9.8 4.1 0.41 10.9 1.5 1.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Thyroglobulin_1 PF00086.18 PFH35054.1 - 0.05 13.3 0.5 0.13 11.9 0.2 2.0 2 1 1 3 3 3 0 Thyroglobulin type-1 repeat IATP PF04568.12 PFH35055.1 - 3.8 8.0 9.7 0.25 11.8 0.1 3.9 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP Hist_deacetyl PF00850.19 PFH35056.1 - 4.2e-64 217.0 1.8 2.5e-61 207.8 0.2 2.1 1 1 1 2 2 2 2 Histone deacetylase domain PRCC PF10253.9 PFH35057.1 - 4.2e-20 73.5 12.2 4.2e-20 73.5 12.2 3.3 1 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting RIO1 PF01163.22 PFH35058.1 - 6.4e-45 153.1 0.2 1.4e-44 152.0 0.2 1.5 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 PFH35058.1 - 2.2e-33 114.3 0.9 5.9e-32 109.7 0.3 2.4 2 0 0 2 2 2 1 Rio2, N-terminal Kdo PF06293.14 PFH35058.1 - 3.9e-07 29.6 0.3 8.5e-06 25.3 0.3 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH35058.1 - 3.2e-06 27.3 10.3 3.2e-05 24.0 0.2 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PFH35058.1 - 0.16 11.3 0.1 0.25 10.6 0.1 1.2 1 0 0 1 1 1 0 Kinase-like SDA1 PF05285.12 PFH35058.1 - 0.94 8.8 32.8 1.5 8.2 32.8 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 PFH35058.1 - 1.7 6.7 34.4 2.6 6.0 34.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 PFH35058.1 - 1.8 7.8 34.5 2.6 7.3 34.5 1.2 1 0 0 1 1 1 0 BUD22 Glutaredoxin PF00462.24 PFH35059.1 - 1e-14 54.5 0.1 1.6e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 PFH35059.1 - 0.00043 20.2 0.3 0.00089 19.1 0.0 1.6 2 0 0 2 2 2 1 F plasmid transfer operon protein DUF836 PF05768.14 PFH35059.1 - 0.02 15.3 0.0 0.031 14.7 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) NIF PF03031.18 PFH35059.1 - 0.028 14.2 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Thioredoxin_2 PF13098.6 PFH35059.1 - 0.094 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain PUA_3 PF17785.1 PFH35060.1 - 2.3e-12 46.5 0.1 6e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 PUA-like domain V_ATPase_I_N PF18670.1 PFH35060.1 - 0.14 12.6 2.8 0.16 12.4 0.1 2.5 3 0 0 3 3 3 0 V-type ATPase subunit I, N-terminal domain Glutaredoxin PF00462.24 PFH35062.1 - 1.2e-05 25.4 0.1 2.1e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin AA_kinase PF00696.28 PFH35063.1 - 2.4e-46 158.3 0.0 4e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 PFH35063.1 - 0.00024 20.8 0.4 0.096 12.5 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 PFH35063.1 - 0.0041 16.9 0.5 0.57 10.0 0.0 2.7 3 0 0 3 3 3 2 ACT domain PI-PLC-X PF00388.19 PFH35063.1 - 0.091 12.3 0.1 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-C1 PF16670.5 PFH35063.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent PCIF1_WW PF12237.8 PFH35064.1 - 5.2e-46 156.4 0.0 8.6e-46 155.7 0.0 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain Exonuc_VII_L PF02601.15 PFH35065.1 - 0.054 13.1 7.1 0.08 12.5 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit THOC7 PF05615.13 PFH35065.1 - 0.24 11.7 15.1 0.18 12.1 12.9 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 Phage_GPO PF05929.11 PFH35065.1 - 0.59 9.7 7.0 1.2 8.7 7.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase V_ATPase_I PF01496.19 PFH35065.1 - 3.6 5.4 6.3 4.8 5.0 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 PFH35065.1 - 6.2 6.9 7.0 3.3 7.8 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 PFH35065.1 - 9 4.8 9.1 16 4.0 9.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A HATPase_c PF02518.26 PFH35067.1 - 4.4e-08 33.6 0.0 2.9e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IMP2_N PF18590.1 PFH35068.1 - 8.9e-25 87.1 0.0 1.1e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 PFH35068.1 - 3.2e-23 81.4 0.2 4.9e-23 80.8 0.2 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) C-terminal domain SIR2 PF02146.17 PFH35069.1 - 1.7e-45 155.1 0.0 2.2e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 PFH35069.1 - 0.00045 20.0 0.0 0.0048 16.6 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Gemini_mov PF01708.16 PFH35070.1 - 0.13 12.1 0.8 0.24 11.2 0.3 1.7 1 1 1 2 2 2 0 Geminivirus putative movement protein DUF4083 PF13314.6 PFH35070.1 - 0.14 12.1 0.3 0.2 11.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Pkinase PF00069.25 PFH35071.1 - 2e-12 47.1 0.0 3.3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PFH35071.1 - 1.2e-09 37.9 0.0 2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH35071.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase LRRFIP PF09738.9 PFH35072.1 - 0.0009 18.8 0.0 0.0009 18.8 0.0 4.7 3 1 0 3 3 3 1 LRRFIP family GAS PF13851.6 PFH35073.1 - 0.3 10.4 6.5 0.54 9.6 6.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Angiomotin_C PF12240.8 PFH35073.1 - 4.1 6.9 10.2 0.29 10.7 4.9 1.7 2 0 0 2 2 2 0 Angiomotin C terminal SlyX PF04102.12 PFH35074.1 - 2.2 8.9 4.3 7.7 7.2 0.1 3.2 3 0 0 3 3 3 0 SlyX eIF3_subunit PF08597.10 PFH35075.1 - 4.9e-21 75.7 12.9 7.3e-21 75.2 12.9 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF724 PF05266.14 PFH35075.1 - 0.74 9.6 5.4 0.39 10.5 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) tRNA_synt_1c_R2 PF04557.15 PFH35075.1 - 3 8.8 9.6 0.52 11.3 1.0 2.6 3 0 0 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Seryl_tRNA_N PF02403.22 PFH35075.1 - 5.6 7.3 11.8 0.14 12.4 1.5 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2408 PF10303.9 PFH35075.1 - 6.5 7.3 7.6 0.86 10.2 0.9 2.5 2 2 1 3 3 3 0 Protein of unknown function (DUF2408) Ribosomal_S17_N PF16205.5 PFH35076.1 - 8.5e-29 99.8 0.5 1.5e-28 99.0 0.5 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 PFH35076.1 - 5.7e-24 84.0 0.3 1e-23 83.2 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 PFK PF00365.20 PFH35077.1 - 6.9e-45 153.6 0.9 1.4e-36 126.3 0.0 3.8 2 2 0 2 2 2 2 Phosphofructokinase DHR10 PF18595.1 PFH35079.1 - 6.3e-06 26.2 4.6 6.3e-06 26.2 4.6 4.3 4 0 0 4 4 4 1 Designed helical repeat protein 10 domain BLOC1_2 PF10046.9 PFH35079.1 - 0.026 14.8 2.8 3.5 8.0 0.5 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 PFH35079.1 - 0.45 11.0 1.3 0.57 10.7 0.1 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein UCH PF00443.29 PFH35080.1 - 5.3e-38 131.0 0.0 7.2e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PFH35080.1 - 1e-15 58.2 0.0 3.7e-15 56.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cwf_Cwc_15 PF04889.12 PFH35080.1 - 0.014 15.2 11.3 0.58 9.8 7.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein hDGE_amylase PF14701.6 PFH35082.1 - 3.7e-135 451.4 0.0 1.1e-134 449.9 0.0 1.7 1 1 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 PFH35082.1 - 1.7e-113 379.4 0.0 2.5e-113 378.9 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 PFH35082.1 - 5e-49 167.2 0.0 7e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme AMPK1_CBM PF16561.5 PFH35082.1 - 1.1e-08 35.2 1.3 4.3e-08 33.2 1.3 2.0 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase SSXT PF05030.12 PFH35083.1 - 0.0023 17.5 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 SSXT protein (N-terminal region) ORC_WH_C PF18137.1 PFH35084.1 - 2.4e-06 27.7 0.3 2.4e-06 27.7 0.3 6.8 8 1 0 8 8 8 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 PFH35084.1 - 0.31 10.1 15.6 0.0051 15.9 4.6 3.0 4 0 0 4 4 4 0 Origin recognition complex (ORC) subunit 3 N-terminus Tubulin PF00091.25 PFH35086.1 - 2.3e-68 230.3 0.0 3.7e-68 229.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PFH35086.1 - 1.3e-45 154.6 2.0 1.4e-45 154.5 0.7 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PFH35086.1 - 1.2e-06 28.8 0.0 2.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 PFH35086.1 - 0.0047 16.2 0.0 0.0078 15.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin like RabGAP-TBC PF00566.18 PFH35088.1 - 1.3e-51 175.3 0.2 2.1e-51 174.7 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cupin_8 PF13621.6 PFH35088.1 - 6.4e-35 121.1 0.0 2.8e-34 119.0 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 PFH35088.1 - 0.00048 19.7 0.0 0.0022 17.5 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein DUF5344 PF17279.2 PFH35088.1 - 0.11 13.1 0.4 0.25 11.9 0.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5344) HemX PF04375.14 PFH35088.1 - 0.28 10.4 1.3 0.44 9.8 0.8 1.5 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase HSP70 PF00012.20 PFH35089.1 - 7.1e-58 196.2 11.5 1.4e-56 192.0 1.1 4.8 1 1 3 4 4 4 2 Hsp70 protein MreB_Mbl PF06723.13 PFH35089.1 - 2.3e-08 33.3 0.1 5e-08 32.1 0.1 1.5 1 1 0 1 1 1 1 MreB/Mbl protein SesA PF17107.5 PFH35089.1 - 0.26 11.5 3.3 10 6.3 0.2 3.0 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NPV_P10 PF05531.12 PFH35089.1 - 0.73 10.3 5.1 0.64 10.5 0.2 3.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein BUD22 PF09073.10 PFH35089.1 - 2 7.7 45.7 51 3.0 45.2 2.5 1 1 1 2 2 2 0 BUD22 CRR7 PF12095.8 PFH35089.1 - 7.6 7.1 8.9 13 6.3 0.2 4.1 4 1 0 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 PPI_Ypi1 PF07491.11 PFH35090.1 - 2.1e-21 75.5 3.1 4.5e-21 74.4 3.1 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor Bromodomain PF00439.25 PFH35091.1 - 1.7e-15 56.8 0.0 2.7e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain SET PF00856.28 PFH35091.1 - 1.1e-14 55.2 0.1 1.1e-14 55.2 0.1 3.7 2 1 0 2 2 2 1 SET domain PHD PF00628.29 PFH35091.1 - 3.2e-06 26.9 64.5 0.0001 22.1 0.4 7.9 8 0 0 8 8 8 4 PHD-finger zf-HC5HC2H PF13771.6 PFH35091.1 - 2e-05 24.8 0.2 2e-05 24.8 0.2 4.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PFH35091.1 - 0.0021 18.2 1.0 0.0021 18.2 1.0 4.1 4 0 0 4 4 4 1 PHD-zinc-finger like domain HTH_23 PF13384.6 PFH35091.1 - 0.06 13.2 0.1 0.22 11.3 0.1 1.9 1 0 0 1 1 1 0 Homeodomain-like domain GSH_synth_ATP PF03917.17 PFH35092.1 - 2e-62 211.2 0.0 8.8e-17 60.9 0.0 5.8 5 1 0 5 5 5 5 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 PFH35092.1 - 6.4e-19 68.3 0.0 5.7e-18 65.3 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic glutathione synthase ABC_tran PF00005.27 PFH35093.1 - 4.3e-40 137.4 0.1 1.3e-20 74.3 0.0 4.3 4 1 0 4 4 3 3 ABC transporter AAA_21 PF13304.6 PFH35093.1 - 2.9e-18 66.7 5.9 5.5e-05 23.1 0.0 5.0 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PFH35093.1 - 3e-10 39.9 0.1 0.069 12.6 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PFH35093.1 - 4.7e-09 37.0 1.6 0.0024 18.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 PFH35093.1 - 4.2e-06 26.4 0.1 0.0072 16.0 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 PFH35093.1 - 9e-06 25.5 0.0 0.12 12.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 PFH35093.1 - 2.2e-05 24.4 0.0 0.085 12.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 PFH35093.1 - 2.8e-05 24.0 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 PFH35093.1 - 4.9e-05 23.6 0.8 0.51 10.6 0.0 3.2 4 0 0 4 4 2 2 AAA domain NACHT PF05729.12 PFH35093.1 - 0.00015 21.7 0.0 0.3 11.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 PFH35093.1 - 0.00017 21.7 0.1 0.022 14.8 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 PFH35093.1 - 0.00054 20.4 0.0 1.7 9.1 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PFH35093.1 - 0.00096 19.2 0.1 0.33 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 PFH35093.1 - 0.0011 19.6 0.3 0.47 11.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 PFH35093.1 - 0.0018 18.5 0.1 0.2 11.9 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 PFH35093.1 - 0.0026 17.3 0.1 0.68 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PFH35093.1 - 0.003 17.7 0.2 0.95 9.6 0.1 3.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PFH35093.1 - 0.0044 17.3 3.5 0.22 11.8 0.0 3.3 4 0 0 4 4 2 1 AAA domain Roc PF08477.13 PFH35093.1 - 0.0061 16.8 0.0 5.4 7.3 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 PFH35093.1 - 0.0091 15.6 0.1 4.2 6.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PFH35093.1 - 0.01 15.6 0.1 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 PFH35093.1 - 0.011 15.3 0.1 4.7 6.8 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 PFH35093.1 - 0.019 14.5 0.0 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 PFH35093.1 - 0.027 14.1 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 PFH35093.1 - 0.037 14.0 0.1 4.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 PFH35093.1 - 0.04 13.6 0.2 0.37 10.5 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Mg_chelatase PF01078.21 PFH35093.1 - 0.043 13.2 0.6 15 4.9 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 PFH35093.1 - 0.047 14.1 0.0 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 PFH35093.1 - 0.052 13.5 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 PFH35093.1 - 0.07 13.0 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 PFH35093.1 - 0.1 12.5 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_16 PF13191.6 PFH35093.1 - 0.14 12.5 21.9 0.24 11.8 2.3 4.5 2 2 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.6 PFH35093.1 - 0.16 10.6 0.0 12 4.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain zf-C3HC4_2 PF13923.6 PFH35094.1 - 5.5e-09 35.7 11.2 9.2e-09 35.0 11.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PFH35094.1 - 6e-06 26.0 10.9 9.9e-06 25.3 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PFH35094.1 - 9.2e-06 25.9 11.4 1.5e-05 25.2 11.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PFH35094.1 - 0.00039 20.2 14.4 0.00059 19.6 14.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH35094.1 - 0.00042 20.3 10.9 0.00084 19.3 10.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PFH35094.1 - 0.0033 17.4 10.9 0.0052 16.7 10.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain SDA1 PF05285.12 PFH35094.1 - 0.0093 15.4 10.6 0.017 14.6 10.6 1.3 1 0 0 1 1 1 1 SDA1 zf-Nse PF11789.8 PFH35094.1 - 0.046 13.5 7.5 0.089 12.6 7.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 PFH35094.1 - 0.083 13.1 11.1 0.15 12.3 11.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PFH35094.1 - 0.15 11.9 9.7 0.32 10.9 9.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Nop14 PF04147.12 PFH35094.1 - 0.19 9.9 12.7 0.29 9.3 12.7 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C3HC4_5 PF17121.5 PFH35094.1 - 0.32 10.9 7.8 0.74 9.7 7.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CDC45 PF02724.14 PFH35094.1 - 0.76 8.0 15.8 1.2 7.4 15.8 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-rbx1 PF12678.7 PFH35094.1 - 0.81 10.0 8.1 1.9 8.9 8.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 PFH35094.1 - 4.5 7.1 10.5 9.3 6.1 10.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PDEase_I PF00233.19 PFH35095.1 - 1.5e-54 185.2 0.0 1.5e-52 178.7 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase zf-RING_2 PF13639.6 PFH35096.1 - 1.4e-13 51.0 3.8 2.9e-13 49.9 3.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PFH35096.1 - 1.2e-09 37.7 2.2 2.8e-09 36.6 2.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PFH35096.1 - 8.9e-08 31.8 2.9 1.9e-07 30.8 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PFH35096.1 - 5.1e-07 29.5 1.6 1.1e-06 28.4 1.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PFH35096.1 - 5.9e-07 29.7 4.7 1.9e-06 28.0 4.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PFH35096.1 - 7.1e-06 25.9 8.4 1.7e-05 24.7 8.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PFH35096.1 - 2.2e-05 24.3 1.3 5.2e-05 23.1 1.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_1 PF14446.6 PFH35096.1 - 0.0016 18.4 1.2 0.0016 18.4 1.2 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 PFH35096.1 - 0.016 15.1 7.0 0.031 14.2 7.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 PFH35096.1 - 0.026 14.4 2.3 0.062 13.2 2.3 1.6 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 PFH35096.1 - 0.042 13.5 6.7 0.094 12.4 6.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf_Rg PF17915.1 PFH35096.1 - 0.059 12.8 1.6 0.17 11.3 1.6 1.8 1 0 0 1 1 1 0 Reverse gyrase zinc finger Prok-RING_4 PF14447.6 PFH35096.1 - 0.13 12.2 9.2 0.25 11.2 9.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PFH35096.1 - 0.22 11.6 8.8 0.21 11.6 6.4 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger 7tm_1 PF00001.21 PFH35096.1 - 0.31 10.3 4.7 0.49 9.7 4.6 1.3 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Aconitase PF00330.20 PFH35097.1 - 2.7e-181 603.6 0.0 3.4e-181 603.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 PFH35097.1 - 4.9e-44 149.8 0.0 8.8e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Surp PF01805.20 PFH35097.1 - 0.051 13.6 0.4 0.12 12.4 0.4 1.5 1 0 0 1 1 1 0 Surp module Translin PF01997.16 PFH35098.1 - 2e-25 90.0 2.8 2.4e-24 86.5 2.8 2.0 1 1 0 1 1 1 1 Translin family Vta1_C PF18097.1 PFH35098.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Vta1 C-terminal domain DUF3522 PF12036.8 PFH35099.1 - 3.9e-28 99.0 5.5 3.9e-28 99.0 5.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3522) Sdh_cyt PF01127.22 PFH35100.1 - 0.025 14.6 0.1 0.04 14.0 0.1 1.3 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SNase PF00565.17 PFH35101.1 - 1.7e-18 67.1 0.0 1.1e-12 48.4 0.0 2.4 2 0 0 2 2 2 2 Staphylococcal nuclease homologue Pertus-S4-tox PF09275.10 PFH35104.1 - 0.025 14.8 0.6 0.08 13.2 0.6 1.8 1 0 0 1 1 1 0 Pertussis toxin S4 subunit Yippee-Mis18 PF03226.14 PFH35108.1 - 4.8e-16 58.9 0.6 6.2e-16 58.5 0.6 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.6 PFH35108.1 - 0.012 15.4 1.3 2.4 8.1 0.3 2.3 2 0 0 2 2 2 0 HNH endonuclease GFA PF04828.14 PFH35108.1 - 0.017 15.4 1.8 0.59 10.5 0.1 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme RIG-I_C-RD PF11648.8 PFH35108.1 - 0.026 14.8 0.3 0.034 14.4 0.3 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I C1_2 PF03107.16 PFH35108.1 - 0.026 14.8 1.8 3.2 8.2 0.2 2.3 2 0 0 2 2 2 0 C1 domain DUF3268 PF11672.8 PFH35108.1 - 0.026 14.8 0.6 0.77 10.1 0.0 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain DZR PF12773.7 PFH35108.1 - 0.026 14.5 0.3 5.8 7.0 0.2 2.2 2 0 0 2 2 2 0 Double zinc ribbon zf_UBZ PF18439.1 PFH35108.1 - 0.038 13.6 0.5 0.53 9.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_6 PF14599.6 PFH35108.1 - 0.041 13.9 1.0 0.16 12.0 0.1 2.1 2 0 0 2 2 2 0 Zinc-ribbon zf-B_box PF00643.24 PFH35108.1 - 0.2 11.9 2.5 8.9 6.6 0.1 2.3 2 0 0 2 2 2 0 B-box zinc finger His_Phos_1 PF00300.22 PFH35111.1 - 3.1e-08 33.6 0.0 4.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CEP76-C2 PF15627.6 PFH35112.1 - 2.9e-13 49.7 1.2 3.2e-08 33.3 0.2 2.4 1 1 1 2 2 2 2 CEP76 C2 domain SNARE PF05739.19 PFH35113.1 - 3.8e-12 46.0 1.6 1.2e-11 44.4 0.5 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 PFH35113.1 - 0.0025 17.5 10.0 0.0025 17.5 10.0 2.7 2 1 1 3 3 3 1 Syntaxin SF-assemblin PF06705.11 PFH35113.1 - 0.015 14.7 6.0 0.018 14.4 1.7 2.3 2 0 0 2 2 2 0 SF-assemblin/beta giardin CSM2 PF16834.5 PFH35113.1 - 0.04 13.5 2.8 0.084 12.5 2.8 1.5 1 0 0 1 1 1 0 Shu complex component Csm2, DNA-binding DUF3540 PF12059.8 PFH35113.1 - 0.052 13.4 5.1 0.063 13.1 0.7 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3540) AI-2E_transport PF01594.16 PFH35113.1 - 0.1 11.7 5.2 0.079 12.1 1.1 2.0 2 0 0 2 2 2 0 AI-2E family transporter Syntaxin_2 PF14523.6 PFH35113.1 - 0.17 12.3 12.3 8.8 6.8 7.2 3.2 2 1 0 2 2 2 0 Syntaxin-like protein Syntaxin-6_N PF09177.11 PFH35113.1 - 0.29 11.7 5.1 2.3 8.8 1.5 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Streptin-Immun PF11083.8 PFH35113.1 - 0.39 11.1 5.0 0.45 10.9 1.3 2.3 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein CorA PF01544.18 PFH35113.1 - 0.57 9.4 11.3 0.5 9.6 3.2 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein KxDL PF10241.9 PFH35113.1 - 0.71 10.2 13.5 2.1 8.7 3.2 3.8 2 2 2 4 4 4 0 Uncharacterized conserved protein Baculo_PEP_C PF04513.12 PFH35113.1 - 0.83 9.7 7.4 0.98 9.5 0.2 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF148 PF02520.17 PFH35113.1 - 3.7 7.7 9.0 0.36 10.9 0.4 2.5 2 1 1 3 3 3 0 Domain of unknown function DUF148 COX2 PF00116.20 PFH35114.1 - 0.0071 16.2 0.4 0.014 15.2 0.1 1.6 2 0 0 2 2 2 1 Cytochrome C oxidase subunit II, periplasmic domain SAG PF04092.13 PFH35115.1 - 1.6e-05 25.7 0.5 2.1e-05 25.3 0.5 1.1 1 0 0 1 1 1 1 SRS domain zf-CCCH PF00642.24 PFH35118.1 - 8e-09 35.2 3.1 8e-09 35.2 3.1 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 PFH35118.1 - 1.6e-06 27.9 10.3 3e-06 27.1 10.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PFH35118.1 - 1.7e-05 24.6 6.8 3.6e-05 23.5 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 PFH35118.1 - 0.00032 20.7 5.4 0.00032 20.7 5.4 2.2 2 0 0 2 2 2 1 Zinc finger domain zf-RING_UBOX PF13445.6 PFH35118.1 - 0.00033 20.6 6.1 0.00078 19.4 6.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 PFH35118.1 - 0.00067 19.7 3.8 0.00067 19.7 3.8 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 PFH35118.1 - 0.0036 17.6 8.7 0.0079 16.5 8.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 PFH35118.1 - 0.006 16.4 2.6 0.006 16.4 2.6 2.1 2 0 0 2 2 1 1 CCCH-type zinc finger zf-C3HC4 PF00097.25 PFH35118.1 - 0.017 15.0 10.9 0.044 13.7 10.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PFH35118.1 - 0.033 14.0 5.5 0.069 13.0 5.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PFH35118.1 - 0.087 12.7 8.3 0.32 10.9 8.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PFH35118.1 - 0.26 11.5 10.5 0.094 12.9 5.7 2.5 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PFH35118.1 - 0.63 10.4 6.1 1.6 9.1 6.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain DZR PF12773.7 PFH35118.1 - 4.1 7.5 8.2 13 5.9 8.1 1.8 1 1 0 1 1 1 0 Double zinc ribbon DUF4674 PF15719.5 PFH35118.1 - 4.2 7.4 7.2 1.6 8.7 1.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4674) RabGAP-TBC PF00566.18 PFH35119.1 - 5.2e-17 62.2 0.1 8.8e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 PFH35120.1 - 7.8e-47 159.9 0.0 9.4e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35120.1 - 1.9e-19 70.0 0.0 2.7e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH35120.1 - 0.00016 21.7 0.1 0.00039 20.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PFH35120.1 - 0.00033 20.1 0.0 0.00066 19.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PFH35120.1 - 0.00065 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 PFH35120.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 PFH35120.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 PFH35120.1 - 0.23 10.4 0.0 0.38 9.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 PFH35120.1 - 0.25 10.1 0.0 0.4 9.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Nramp PF01566.18 PFH35121.1 - 0.0089 15.0 0.5 0.016 14.2 0.5 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF2627 PF11118.8 PFH35121.1 - 0.13 12.8 0.4 3.1 8.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) ThrE PF06738.12 PFH35121.1 - 0.76 9.1 5.6 0.35 10.2 2.6 1.9 2 0 0 2 2 2 0 Putative threonine/serine exporter LSM PF01423.22 PFH35122.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain Sec23_trunk PF04811.15 PFH35123.1 - 6.7e-23 81.5 0.0 6.5e-22 78.3 0.0 2.0 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 PFH35123.1 - 4.9e-21 74.5 0.0 1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 PFH35123.1 - 3.2e-10 39.9 7.8 6.4e-10 38.9 7.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 PFH35123.1 - 3e-06 27.9 0.1 3e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain VMA21 PF09446.10 PFH35124.1 - 0.054 13.6 0.1 0.081 13.0 0.1 1.2 1 0 0 1 1 1 0 VMA21-like domain Topoisom_bac PF01131.20 PFH35125.1 - 3.6e-104 349.0 0.0 4.6e-104 348.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 PFH35125.1 - 7.7e-14 51.8 0.0 1.4e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Hydrolase_4 PF12146.8 PFH35126.1 - 0.0034 16.7 0.0 0.046 13.0 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PFH35126.1 - 0.095 12.3 0.0 0.58 9.8 0.0 2.3 3 0 0 3 3 3 0 alpha/beta hydrolase fold SNAPc_SNAP43 PF09808.9 PFH35127.1 - 0.093 12.7 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 TMEM100 PF16311.5 PFH35128.1 - 0.071 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 VIT1 PF01988.19 PFH35128.1 - 0.27 11.1 11.5 7.1 6.4 11.2 2.6 1 1 0 1 1 1 0 VIT family DUF3040 PF11239.8 PFH35128.1 - 1.6 9.1 6.7 6 7.2 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) SNF2_N PF00176.23 PFH35129.1 - 3.9e-48 164.0 0.0 2.7e-24 85.5 0.0 4.2 3 1 0 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.31 PFH35129.1 - 2e-16 60.3 0.0 4.1e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SAP PF02037.27 PFH35129.1 - 1.7e-08 34.0 0.2 5.6e-08 32.4 0.2 2.0 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.6 PFH35129.1 - 3.4e-06 27.3 0.6 3.4e-06 27.3 0.6 2.8 2 0 0 2 2 1 1 Ring finger domain zf-PARP PF00645.18 PFH35129.1 - 0.0002 22.2 0.0 0.00065 20.5 0.0 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-RING_11 PF17123.5 PFH35129.1 - 0.00042 20.0 1.6 0.0011 18.7 1.6 1.8 1 0 0 1 1 1 1 RING-like zinc finger UBA PF00627.31 PFH35129.1 - 0.00044 20.1 1.5 0.001 19.0 0.3 2.3 2 0 0 2 2 1 1 UBA/TS-N domain zf-RING_UBOX PF13445.6 PFH35129.1 - 0.0038 17.2 0.9 0.0038 17.2 0.9 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-C2HC_2 PF13913.6 PFH35129.1 - 0.0039 17.0 0.2 0.0039 17.0 0.2 2.0 2 0 0 2 2 1 1 zinc-finger of a C2HC-type zf-C3HC4 PF00097.25 PFH35129.1 - 0.004 17.0 0.5 0.004 17.0 0.5 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PFH35129.1 - 0.015 15.2 0.4 0.015 15.2 0.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PFH35129.1 - 0.017 15.4 0.1 0.056 13.7 0.1 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain PHD PF00628.29 PFH35129.1 - 0.83 9.6 4.8 1.8 8.5 2.8 2.7 2 1 0 2 2 2 0 PHD-finger Reticulon PF02453.17 PFH35130.1 - 1.8e-14 54.0 10.2 2.3e-14 53.7 10.2 1.1 1 0 0 1 1 1 1 Reticulon DUF2070 PF09843.9 PFH35130.1 - 6.4 4.9 7.3 8.6 4.5 7.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PrgI PF12666.7 PFH35130.1 - 6.9 7.4 8.8 2 9.2 1.2 2.1 2 0 0 2 2 2 0 PrgI family protein Peptidase_M3 PF01432.20 PFH35131.1 - 5.5e-26 91.8 0.3 5.5e-26 91.8 0.3 2.5 3 0 0 3 3 3 2 Peptidase family M3 Peptidase_M3_N PF08439.10 PFH35131.1 - 1.7e-06 28.2 0.0 5.3e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Oligopeptidase F EF1_GNE PF00736.19 PFH35132.1 - 1e-30 105.7 3.0 1e-30 105.7 3.0 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain DUF4315 PF14193.6 PFH35132.1 - 0.0023 17.9 0.6 0.0023 17.9 0.6 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4315) PTPRCAP PF15713.5 PFH35132.1 - 0.0058 16.9 1.3 0.0058 16.9 1.3 2.1 2 0 0 2 2 2 1 Protein tyrosine phosphatase receptor type C-associated Costars PF14705.6 PFH35132.1 - 0.073 13.3 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 Costars F420_oxidored PF03807.17 PFH35132.1 - 0.39 11.3 1.8 1.3 9.7 0.6 2.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent FAM176 PF14851.6 PFH35132.1 - 0.55 9.9 4.9 0.82 9.3 0.3 2.2 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 PFH35132.1 - 1.5 9.3 10.2 2.3 8.6 3.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA2 PF07543.12 PFH35132.1 - 3.7 7.5 11.0 1.7 8.6 1.2 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Med2 PF11214.8 PFH35132.1 - 7.6 6.8 9.6 2.4 8.4 2.1 3.0 4 0 0 4 4 4 0 Mediator complex subunit 2 Radical_SAM PF04055.21 PFH35133.1 - 2e-13 51.0 0.0 5.2e-13 49.7 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily LIAS_N PF16881.5 PFH35133.1 - 5.8e-06 26.7 0.1 3e-05 24.4 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family B12-binding PF02310.19 PFH35133.1 - 0.16 12.0 0.0 10 6.2 0.0 2.6 2 1 0 2 2 2 0 B12 binding domain Hydrolase_4 PF12146.8 PFH35134.1 - 5.3e-19 68.4 0.1 2.2e-07 30.4 0.3 4.2 4 0 0 4 4 4 4 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PFH35134.1 - 0.0017 19.0 9.7 0.0018 19.0 5.8 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PFH35134.1 - 0.12 12.0 0.7 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Consortin_C PF15281.6 PFH35135.1 - 0.033 14.2 0.2 0.072 13.1 0.0 1.6 2 0 0 2 2 2 0 Consortin C-terminus REV PF00424.18 PFH35135.1 - 0.091 12.8 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) CPP1-like PF11833.8 PFH35135.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DAGAT PF03982.13 PFH35137.1 - 1.2e-73 247.6 0.0 1.6e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 PFH35137.1 - 0.0021 17.7 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase SNF5 PF04855.12 PFH35138.1 - 0.012 15.5 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 PH_17 PF18012.1 PFH35140.1 - 0.094 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 PH domain Prominin PF05478.11 PFH35140.1 - 0.25 9.3 0.1 0.38 8.7 0.1 1.1 1 0 0 1 1 1 0 Prominin Qua1 PF16274.5 PFH35141.1 - 0.01 15.6 0.1 7.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Qua1 domain RRM_5 PF13893.6 PFH35142.1 - 0.026 14.1 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med3 PF11593.8 PFH35142.1 - 2.6 7.1 5.2 8 5.5 5.2 1.8 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-CCCH PF00642.24 PFH35143.1 - 1.6e-08 34.3 22.7 0.00036 20.4 0.1 4.9 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PFH35143.1 - 7e-06 25.7 17.3 3.2e-05 23.6 0.9 4.0 4 0 0 4 4 4 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PFH35143.1 - 2.8e-05 24.0 30.4 0.062 13.4 3.2 5.0 5 0 0 5 5 5 3 Zinc finger domain Torus PF16131.5 PFH35143.1 - 0.0039 17.9 14.7 0.038 14.7 0.7 4.4 2 1 2 4 4 4 1 Torus domain zf-CCCH_3 PF15663.5 PFH35143.1 - 0.11 12.7 10.2 0.2 11.9 4.4 2.4 2 0 0 2 2 2 0 Zinc-finger containing family zf_CCCH_5 PF18384.1 PFH35143.1 - 3.3 7.9 4.7 0.55 10.4 0.5 1.9 2 0 0 2 2 2 0 Unkempt Zinc finger domain 1 (Znf1) zf-CCCH_2 PF14608.6 PFH35143.1 - 4.1 8.0 12.7 15 6.3 0.1 4.7 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger CAP_N PF01213.19 PFH35143.1 - 4.6 6.6 4.7 11 5.4 4.7 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal adh_short_C2 PF13561.6 PFH35144.1 - 9.7e-46 156.2 2.2 2e-19 70.1 0.3 3.1 3 0 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PFH35144.1 - 4.8e-34 117.5 1.3 1.9e-24 86.2 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 PFH35144.1 - 1.3e-05 25.2 0.1 2.6e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 KR domain Exonuc_VII_L PF02601.15 PFH35145.1 - 0.68 9.5 5.5 0.95 9.0 5.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1018 PF06252.12 PFH35145.1 - 3.3 8.7 8.1 80 4.3 6.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) Ribosomal_L28 PF00830.19 PFH35147.1 - 5.6e-05 23.2 0.1 5.6e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 Ribosomal L28 family DUF2053 PF09767.9 PFH35148.1 - 1.3e-40 139.2 8.3 1.7e-40 138.8 8.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) DctQ PF04290.12 PFH35148.1 - 4 7.4 19.2 2.7 7.9 12.2 2.4 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2070 PF09843.9 PFH35148.1 - 6.3 5.0 15.4 17 3.6 15.6 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) DEAD PF00270.29 PFH35149.1 - 1.4e-48 165.0 0.0 3e-48 163.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH35149.1 - 2.1e-33 114.9 0.0 4.5e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UTP25 PF06862.12 PFH35149.1 - 0.16 10.7 0.0 0.32 9.7 0.0 1.4 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 PFH35149.1 - 0.17 12.2 0.0 4.1 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Thioredoxin_8 PF13905.6 PFH35149.1 - 0.23 11.8 0.0 0.47 10.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Prok-RING_2 PF14445.6 PFH35150.1 - 0.00052 20.1 8.7 0.053 13.7 1.1 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 2 Herpes_UL73 PF03554.13 PFH35150.1 - 0.42 10.6 2.5 12 6.0 0.2 2.6 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein RXLR PF16810.5 PFH35151.1 - 0.026 14.9 1.2 0.051 14.0 1.2 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Miff PF05644.11 PFH35151.1 - 0.098 12.3 2.8 0.13 11.8 2.8 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff zf-C2H2_jaz PF12171.8 PFH35152.1 - 2e-09 37.5 0.7 2.8e-09 37.0 0.7 1.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PFH35152.1 - 0.00072 19.9 0.3 0.0011 19.3 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PFH35152.1 - 0.018 15.3 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Atg14 PF10186.9 PFH35152.1 - 0.38 9.8 3.1 8.8 5.3 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 IMCp PF12314.8 PFH35154.1 - 1.1e-16 60.9 133.3 4.6e-08 33.2 27.2 5.8 1 1 5 6 6 6 5 Inner membrane complex protein E1-E2_ATPase PF00122.20 PFH35155.1 - 1.7e-34 119.0 2.8 4.3e-28 98.1 0.0 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 PFH35155.1 - 2.2e-26 93.4 4.7 4.6e-15 56.5 0.3 3.6 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HMA PF00403.26 PFH35155.1 - 1.4e-08 35.1 0.1 3.5e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 PFH35155.1 - 0.022 14.5 0.2 0.33 10.7 0.2 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DEAD PF00270.29 PFH35156.1 - 1.3e-26 93.5 0.0 2.4e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH35156.1 - 1.4e-22 80.1 0.0 4.3e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.12 PFH35156.1 - 0.00081 19.6 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 GUCT (NUC152) domain PAP_central PF04928.17 PFH35157.1 - 1.2e-90 302.9 0.0 1.6e-90 302.4 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 PFH35157.1 - 1.9e-15 56.9 0.0 2e-08 34.0 0.1 2.4 2 0 0 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 PFH35157.1 - 8e-12 45.3 0.0 1.6e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Metallophos PF00149.28 PFH35158.1 - 0.00029 21.4 0.0 0.00089 19.8 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DnaJ PF00226.31 PFH35159.1 - 1e-18 67.2 0.1 2e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Aa_trans PF01490.18 PFH35161.1 - 1.2e-51 175.8 0.0 7e-51 173.2 0.0 2.1 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 PFH35161.1 - 3.7e-05 22.9 7.5 6.3e-05 22.2 7.5 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family IBR PF01485.21 PFH35162.1 - 1.9e-10 40.8 26.0 1.3e-05 25.3 2.5 3.3 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain SPX PF03105.19 PFH35162.1 - 8.3 6.2 8.4 11 5.8 0.3 2.5 2 1 0 2 2 2 0 SPX domain EF-hand_7 PF13499.6 PFH35163.1 - 5.9e-10 39.5 0.0 0.00044 20.7 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH35163.1 - 5.8e-08 32.1 0.0 0.00051 19.8 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.6 PFH35163.1 - 7.7e-07 29.3 0.1 0.03 14.6 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 PFH35163.1 - 1.4e-06 27.5 0.3 0.0026 17.2 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PFH35163.1 - 3.4e-06 26.8 4.2 0.27 11.1 0.0 4.0 2 1 1 3 3 3 3 EF-hand domain pair Pkinase PF00069.25 PFH35164.1 - 3.7e-64 216.6 0.0 4.3e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35164.1 - 1.4e-35 122.8 0.0 1.7e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH35164.1 - 0.00041 19.7 0.0 0.00055 19.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MFS_2 PF13347.6 PFH35165.1 - 1.3e-68 231.6 31.2 1.5e-68 231.3 31.2 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 PFH35165.1 - 9.7e-16 57.6 36.7 1.4e-09 37.4 17.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Pterin_4a PF01329.19 PFH35166.1 - 8.2e-31 106.0 0.5 9.6e-31 105.8 0.5 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Sigma_reg_C PF13791.6 PFH35166.1 - 0.066 13.4 0.1 0.078 13.2 0.1 1.1 1 0 0 1 1 1 0 Sigma factor regulator C-terminal ATP-synt_DE_N PF02823.16 PFH35167.1 - 1.2e-10 41.1 0.0 1.8e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Acyl_transf_1 PF00698.21 PFH35168.1 - 3.5e-22 79.3 5.0 1.4e-15 57.6 3.1 2.1 1 1 1 2 2 2 2 Acyl transferase domain Med31 PF05669.12 PFH35170.1 - 7.2e-33 112.5 1.3 9.4e-33 112.1 1.3 1.1 1 0 0 1 1 1 1 SOH1 DUF2207 PF09972.9 PFH35171.1 - 0.057 12.2 6.1 0.11 11.2 6.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5305 PF17231.2 PFH35171.1 - 4.3 6.7 30.2 0.028 13.8 21.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) BatD PF13584.6 PFH35171.1 - 8 5.1 20.6 12 4.6 19.1 1.9 2 1 0 2 2 2 0 Oxygen tolerance Pkinase PF00069.25 PFH35172.1 - 1.1e-37 129.9 0.0 1.6e-12 47.4 0.0 4.0 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35172.1 - 1.3e-15 57.4 0.0 5.4e-07 29.2 0.0 3.6 4 0 0 4 4 4 3 Protein tyrosine kinase APH PF01636.23 PFH35172.1 - 0.0029 17.6 0.0 0.01 15.8 0.0 2.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family LPAM_1 PF08139.12 PFH35173.1 - 5.5 7.7 6.9 1.7 9.3 3.2 2.1 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site MLTD_N PF06474.12 PFH35173.1 - 7.8 6.8 7.8 28 5.0 4.4 2.4 2 0 0 2 2 2 0 MltD lipid attachment motif IMP2_N PF18590.1 PFH35175.1 - 2.1e-28 98.7 0.1 3.6e-28 97.9 0.1 1.4 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 PFH35175.1 - 7.1e-08 32.2 0.5 1.3e-07 31.3 0.5 1.4 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) C-terminal domain DUF3945 PF13101.6 PFH35175.1 - 0.058 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) TIM PF00121.18 PFH35176.1 - 1.3e-86 290.0 0.0 1.4e-86 289.8 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MSA_2 PF00985.17 PFH35179.1 - 1.9 8.8 4.5 0.46 10.8 0.7 1.9 2 0 0 2 2 2 0 Merozoite Surface Antigen 2 (MSA-2) family PWWP PF00855.17 PFH35180.1 - 0.0012 19.2 0.3 0.0031 17.9 0.3 1.6 1 0 0 1 1 1 1 PWWP domain GDP_Man_Dehyd PF16363.5 PFH35181.1 - 2.1e-48 165.5 0.0 3.5e-48 164.7 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PFH35181.1 - 6e-47 160.1 0.0 7.8e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PFH35181.1 - 1.5e-14 53.7 0.0 1.9e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 PFH35181.1 - 1e-12 47.8 0.0 4.6e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 PFH35181.1 - 2.2e-11 43.4 0.0 4.2e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 PFH35181.1 - 3.5e-06 27.0 0.0 0.00037 20.4 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 PFH35181.1 - 4.6e-06 26.0 0.0 1.4e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 PFH35181.1 - 1.7e-05 24.8 0.0 3.9e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 PFH35181.1 - 0.0022 17.5 0.0 0.021 14.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Glyco_transf_5 PF08323.11 PFH35181.1 - 0.0061 16.3 0.0 0.67 9.6 0.0 2.2 2 0 0 2 2 2 1 Starch synthase catalytic domain UDPG_MGDP_dh_N PF03721.14 PFH35181.1 - 0.047 13.3 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_M28 PF04389.17 PFH35185.1 - 1.6e-27 96.5 0.0 2.4e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Exonuc_VII_L PF02601.15 PFH35187.1 - 0.37 10.3 12.2 0.58 9.7 12.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit RR_TM4-6 PF06459.12 PFH35187.1 - 2 8.2 25.2 5 6.9 25.2 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Acyl_transf_3 PF01757.22 PFH35188.1 - 0.032 13.3 9.8 0.084 11.9 0.1 2.3 2 0 0 2 2 2 0 Acyltransferase family Mitoc_mL59 PF18126.1 PFH35189.1 - 1.3e-05 25.5 3.4 0.0069 16.7 0.2 2.4 2 1 0 2 2 2 2 Mitochondrial ribosomal protein mL59 ABC_tran PF00005.27 PFH35190.1 - 3.7e-19 69.6 0.0 6e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PFH35190.1 - 3.5e-06 26.6 0.7 0.025 14.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PFH35190.1 - 0.00083 19.2 0.2 0.067 13.0 0.1 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PFH35190.1 - 0.0046 16.7 0.1 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 PFH35190.1 - 0.0062 15.3 0.0 0.0092 14.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain MutS_V PF00488.21 PFH35190.1 - 0.048 13.7 0.2 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 MutS domain V RsgA_GTPase PF03193.16 PFH35190.1 - 0.077 12.9 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 PFH35190.1 - 0.12 12.0 0.2 3.1 7.3 0.0 2.6 2 2 0 2 2 2 0 AAA domain Thioredoxin_8 PF13905.6 PFH35191.1 - 1.1e-18 67.3 0.0 1.5e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like NMU PF02070.15 PFH35191.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Neuromedin U Pkinase PF00069.25 PFH35193.1 - 3.2e-41 141.5 0.0 5e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35193.1 - 1.3e-38 132.8 0.0 1.9e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH35193.1 - 0.012 15.6 0.5 0.012 15.6 0.5 2.6 2 2 1 3 3 3 0 Phosphotransferase enzyme family Chorein_N PF12624.7 PFH35194.1 - 3.3e-09 36.9 0.0 1e-08 35.3 0.0 1.7 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 SH3-WW_linker PF16618.5 PFH35194.1 - 0.051 14.0 7.2 0.087 13.3 7.2 1.5 1 0 0 1 1 1 0 Linker region between SH3 and WW domains on ARHGAP12 ATG_C PF09333.11 PFH35195.1 - 0.005 17.2 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 PFH35195.1 - 0.12 12.2 0.0 9.2 6.0 0.0 3.0 3 0 0 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal Bclx_interact PF08945.10 PFH35195.1 - 0.5 10.2 4.2 0.18 11.6 0.2 2.3 2 0 0 2 2 2 0 Bcl-x interacting, BH3 domain Nop14 PF04147.12 PFH35195.1 - 3.4 5.8 11.2 5.4 5.1 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family BolA PF01722.18 PFH35197.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 BolA-like protein Tim17 PF02466.19 PFH35198.1 - 8.3e-25 87.3 2.5 1.2e-24 86.8 2.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3947 PF13135.6 PFH35198.1 - 0.055 13.7 0.3 0.14 12.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) TIP120 PF08623.10 PFH35200.1 - 0.86 9.4 3.7 1.5 8.5 3.7 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Nas2_N PF18265.1 PFH35201.1 - 5.9e-25 87.0 0.0 9.4e-25 86.3 0.0 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 PFH35201.1 - 0.0018 18.1 0.0 0.0052 16.6 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PFH35201.1 - 0.018 15.3 0.0 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 PDZ domain TSC22 PF01166.18 PFH35202.1 - 0.013 15.8 45.6 0.14 12.5 0.3 9.7 8 1 0 9 9 9 0 TSC-22/dip/bun family YvrJ PF12841.7 PFH35202.1 - 0.77 9.3 2.7 4.5 6.9 0.0 3.2 2 0 0 2 2 2 0 YvrJ protein family YabA PF06156.13 PFH35202.1 - 1.1 9.9 83.8 1.3 9.7 1.0 9.8 2 1 5 8 8 8 0 Initiation control protein YabA Fib_alpha PF08702.10 PFH35203.1 - 1.7 8.8 6.7 2.8 8.1 5.7 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PS_Dcarbxylase PF02666.15 PFH35205.1 - 8.1e-53 178.9 0.0 1.1e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase MukE PF04288.13 PFH35205.1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 MukE-like family Zip PF02535.22 PFH35207.1 - 2.1e-32 112.7 9.2 1e-23 84.1 3.3 2.7 3 0 0 3 3 3 2 ZIP Zinc transporter 7tm_3 PF00003.22 PFH35207.1 - 8.4 6.0 7.3 1.6 8.4 0.6 2.2 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR RAP PF08373.10 PFH35208.1 - 2e-13 50.2 0.0 3.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 PFH35208.1 - 3.2e-05 24.0 0.0 7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 REase_MTES_1575 Epiglycanin_C PF14654.6 PFH35209.1 - 5.1 7.2 8.2 2.9 8.0 0.1 3.3 2 1 1 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region SYS1 PF09801.9 PFH35210.1 - 5.2e-22 78.5 5.9 2.1e-19 70.1 2.0 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network Pkinase PF00069.25 PFH35211.1 - 4.4e-74 249.2 0.0 8e-74 248.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35211.1 - 1e-28 100.4 0.0 1.3e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 PFH35211.1 - 1.7e-23 80.4 0.0 6.6e-06 25.3 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PFH35211.1 - 2.3e-23 82.4 0.0 3.1e-10 40.4 0.1 2.7 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH35211.1 - 3.4e-20 70.2 0.0 0.00015 21.4 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PFH35211.1 - 3.2e-18 64.3 0.2 4.1e-06 26.0 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PFH35211.1 - 4.4e-18 64.9 0.7 2.6e-05 24.0 0.0 4.1 2 1 2 4 4 4 4 EF-hand domain pair CBM_20 PF00686.19 PFH35211.1 - 3.3e-15 55.8 0.1 5.7e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 Starch binding domain SPARC_Ca_bdg PF10591.9 PFH35211.1 - 4.3e-07 30.2 0.0 0.00046 20.5 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PFH35211.1 - 3.5e-05 23.7 0.0 0.029 14.3 0.0 2.4 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 PFH35211.1 - 0.00023 21.4 0.1 0.71 10.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain Kdo PF06293.14 PFH35211.1 - 0.001 18.5 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Dockerin_1 PF00404.18 PFH35211.1 - 0.0068 16.6 0.2 0.081 13.1 0.1 2.5 2 1 1 3 3 3 2 Dockerin type I domain DUF2807 PF10988.8 PFH35211.1 - 0.0078 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain Smg4_UPF3 PF03467.15 PFH35211.1 - 0.018 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family APH PF01636.23 PFH35211.1 - 0.03 14.2 0.1 0.081 12.8 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1194 PF06707.11 PFH35211.1 - 0.15 11.2 0.0 0.4 9.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) V-ATPase_G PF03179.15 PFH35212.1 - 0.00077 20.0 5.7 0.0014 19.1 5.7 1.4 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit PMSR PF01625.21 PFH35213.1 - 1.8e-55 187.3 0.0 2.3e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DivIC PF04977.15 PFH35214.1 - 0.0059 16.3 7.1 0.19 11.5 1.0 2.3 2 0 0 2 2 2 2 Septum formation initiator SlyX PF04102.12 PFH35214.1 - 0.0062 17.1 0.9 0.0062 17.1 0.9 2.6 3 0 0 3 3 3 1 SlyX APG6_N PF17675.1 PFH35214.1 - 0.039 14.5 1.9 6.7 7.2 0.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 PFH35214.1 - 0.051 12.9 2.4 0.16 11.3 2.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 PFH35214.1 - 0.08 12.9 1.2 1.7 8.7 0.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FliJ PF02050.16 PFH35214.1 - 0.15 12.3 8.3 0.092 13.0 2.1 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Spc7 PF08317.11 PFH35214.1 - 0.21 10.4 2.2 3.4 6.4 0.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4140 PF13600.6 PFH35214.1 - 0.52 10.8 4.4 14 6.2 0.2 2.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HIT PF01230.23 PFH35217.1 - 1.9e-13 51.0 0.0 2.5e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 PFH35217.1 - 0.15 12.5 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding AMMECR1 PF01871.17 PFH35218.1 - 2.9e-27 95.3 0.0 4.3e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 Histone PF00125.24 PFH35219.1 - 5.8e-30 104.3 0.0 1e-29 103.6 0.0 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 PFH35219.1 - 0.0021 18.2 0.0 0.0031 17.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Cmyb_C PF09316.10 PFH35221.1 - 0.1 12.3 2.5 0.2 11.3 2.5 1.5 1 0 0 1 1 1 0 C-myb, C-terminal TMEM18 PF14770.6 PFH35224.1 - 0.0084 16.1 7.0 0.03 14.3 7.0 1.8 1 1 0 1 1 1 1 Transmembrane protein 18 Nop14 PF04147.12 PFH35227.1 - 7.2 4.7 5.0 10 4.2 5.0 1.1 1 0 0 1 1 1 0 Nop14-like family ArfGap PF01412.18 PFH35229.1 - 2.8e-32 111.2 0.0 4.8e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GDA1_CD39 PF01150.17 PFH35230.1 - 1.7e-12 46.7 0.0 8.8e-11 41.1 0.0 3.0 3 1 0 3 3 3 1 GDA1/CD39 (nucleoside phosphatase) family Tropomyosin_1 PF12718.7 PFH35231.1 - 0.031 14.4 41.2 0.026 14.7 9.0 3.8 3 1 0 3 3 3 0 Tropomyosin like DUF3016 PF11454.8 PFH35232.1 - 0.014 15.1 0.8 0.028 14.2 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) FAM184 PF15665.5 PFH35232.1 - 0.055 13.3 16.3 0.11 12.3 16.3 1.5 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Uso1_p115_C PF04871.13 PFH35232.1 - 5.6 7.4 22.3 1.2 9.5 6.8 3.2 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region RNA_pol_Rpb1_5 PF04998.17 PFH35234.1 - 1.1e-99 333.2 0.1 1.5e-99 332.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 PFH35234.1 - 1.4e-97 326.8 0.0 2.2e-97 326.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 PFH35234.1 - 5.9e-73 244.6 0.0 1.2e-72 243.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 PFH35234.1 - 5.2e-51 173.2 3.2 1.4e-50 171.8 2.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 PFH35234.1 - 1.5e-46 157.7 1.4 2e-46 157.3 0.4 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 PFH35234.1 - 1.1e-44 152.2 0.0 2.2e-44 151.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 PFH35234.1 - 1.1e-38 131.5 0.0 2.6e-38 130.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Ribosomal_L14 PF00238.19 PFH35235.1 - 1.1e-23 83.6 0.2 1.3e-23 83.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L13 PF00572.18 PFH35236.1 - 6.2e-36 123.4 0.2 8.8e-36 122.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 CAP PF00188.26 PFH35238.1 - 2.9e-14 54.0 0.0 5e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TSP_1 PF00090.19 PFH35238.1 - 0.0062 16.7 11.6 0.028 14.6 5.5 3.1 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ins_P5_2-kin PF06090.12 PFH35240.1 - 4.8e-20 72.2 0.0 2.4e-09 37.1 0.0 4.2 4 1 0 4 4 4 3 Inositol-pentakisphosphate 2-kinase DUF2273 PF10031.9 PFH35241.1 - 0.48 10.5 10.1 4.7 7.3 3.6 2.3 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF543 PF04418.12 PFH35242.1 - 0.079 13.0 0.4 0.25 11.4 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF543) RIF5_SNase_2 PF18189.1 PFH35242.1 - 0.25 11.1 1.0 2.3 8.0 0.1 2.4 2 0 0 2 2 2 0 TbRIF5 SNase domain 2 BT1 PF03092.16 PFH35244.1 - 5.5e-83 279.0 24.4 8e-54 182.7 12.7 2.1 2 0 0 2 2 2 2 BT1 family S1 PF00575.23 PFH35246.1 - 9.4e-15 54.7 6.1 8.1e-06 26.1 0.1 10.0 11 1 0 11 11 11 2 S1 RNA binding domain Suf PF05843.14 PFH35246.1 - 8.1e-05 22.7 1.9 0.27 11.2 0.3 3.0 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) TPR_6 PF13174.6 PFH35246.1 - 0.048 14.3 0.1 30 5.6 0.0 3.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 PFH35246.1 - 0.066 14.1 0.0 0.066 14.1 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Ribosomal_L39 PF00832.20 PFH35248.1 - 0.1 12.2 0.5 0.96 9.1 0.1 2.2 2 0 0 2 2 2 0 Ribosomal L39 protein Coa1 PF08695.10 PFH35248.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 SUIM_assoc PF16619.5 PFH35249.1 - 0.099 12.7 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 AP2 PF00847.20 PFH35250.1 - 0.0012 19.0 1.7 0.035 14.3 0.1 2.4 2 0 0 2 2 2 2 AP2 domain Snf7 PF03357.21 PFH35251.1 - 6.9e-06 25.8 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Snf7 DUF2561 PF10812.8 PFH35251.1 - 0.65 10.0 4.8 1.9 8.5 4.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) RPW8 PF05659.11 PFH35252.1 - 0.0042 16.8 0.3 0.18 11.5 0.0 2.6 2 0 0 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Mod_r PF07200.13 PFH35252.1 - 0.01 16.0 1.3 0.15 12.2 0.1 2.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Peptidase_M17_N PF02789.17 PFH35252.1 - 0.024 14.5 0.8 0.088 12.7 0.8 2.0 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain E1-E2_ATPase PF00122.20 PFH35252.1 - 0.037 13.6 2.3 0.1 12.1 2.3 1.7 1 0 0 1 1 1 0 E1-E2 ATPase YebG PF07130.12 PFH35252.1 - 0.063 13.1 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 YebG protein DivIC PF04977.15 PFH35253.1 - 0.39 10.5 2.5 21 5.0 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator ANAPC4_WD40 PF12894.7 PFH35254.1 - 0.00042 20.6 0.0 0.037 14.3 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 PFH35254.1 - 0.087 10.8 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 IKI3 family Ribosomal_S13 PF00416.22 PFH35256.1 - 1.6e-52 177.2 3.6 2e-52 177.0 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 PFH35256.1 - 0.01 14.6 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) SecA_SW PF07516.13 PFH35256.1 - 0.12 12.4 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 SecA Wing and Scaffold domain SAG PF04092.13 PFH35258.1 - 1.2e-33 116.7 16.4 1.4e-16 61.4 0.3 2.3 2 1 0 2 2 2 2 SRS domain Herpes_IR6 PF06307.12 PFH35258.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus IR6 protein SAG PF04092.13 PFH35259.1 - 4.2e-36 124.6 8.5 1e-18 68.4 2.6 2.2 2 0 0 2 2 2 2 SRS domain SCPU PF05229.15 PFH35259.1 - 4.4 7.7 11.3 8.9 6.7 6.8 2.5 2 0 0 2 2 2 0 Spore Coat Protein U domain SAG PF04092.13 PFH35260.1 - 3.5e-34 118.4 15.4 3.4e-17 63.5 1.5 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH35261.1 - 1.8e-34 119.4 9.0 5.5e-17 62.8 0.4 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH35262.1 - 2.6e-34 118.9 10.5 5.5e-17 62.8 0.5 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH35263.1 - 3.2e-34 118.6 3.7 1.1e-19 71.5 2.9 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH35264.1 - 3.4e-38 131.4 15.9 1.9e-19 70.8 11.3 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH35265.1 - 2.9e-41 141.3 9.2 2e-22 80.4 0.2 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH35266.1 - 3.1e-32 112.1 17.3 2.9e-16 60.4 1.0 2.1 2 0 0 2 2 2 2 SRS domain InvH PF04741.12 PFH35266.1 - 0.13 12.2 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein SAG PF04092.13 PFH35267.1 - 7.7e-46 156.1 15.6 7.3e-19 68.9 3.2 3.1 3 0 0 3 3 3 3 SRS domain SAG PF04092.13 PFH35269.1 - 6.5e-39 133.7 19.3 1.2e-19 71.4 10.6 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH35270.1 - 8.1e-41 139.9 7.6 3.2e-22 79.7 0.2 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH35271.1 - 6.6e-36 124.0 14.4 9.4e-19 68.5 6.5 2.2 2 0 0 2 2 2 2 SRS domain PARM PF17061.5 PFH35271.1 - 1.9 8.6 13.0 0.071 13.2 3.7 2.1 1 1 1 2 2 2 0 PARM SAG PF04092.13 PFH35272.1 - 4.7e-33 114.8 10.6 5.3e-17 62.8 5.8 2.2 2 0 0 2 2 2 2 SRS domain SVWC PF15430.6 PFH35272.1 - 0.62 10.4 4.6 26 5.2 0.1 2.8 2 0 0 2 2 2 0 Single domain von Willebrand factor type C Thioredoxin_8 PF13905.6 PFH35273.1 - 2.5e-27 95.0 0.0 4.4e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like PUB PF09409.10 PFH35273.1 - 1.3e-11 44.3 0.1 6.8e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 PUB domain Thioredoxin PF00085.20 PFH35273.1 - 2.2e-08 34.0 0.0 4.7e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 PFH35273.1 - 1e-06 29.1 0.0 2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 PFH35273.1 - 1.1e-06 28.4 0.0 2.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 PFH35273.1 - 1.4e-06 28.3 0.0 3.3e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 PFH35273.1 - 0.0055 16.5 0.0 0.046 13.5 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 PFH35273.1 - 0.021 15.0 0.0 0.051 13.8 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 PFH35273.1 - 0.16 12.2 0.0 1.6 9.0 0.0 2.4 1 1 0 1 1 1 0 Glutaredoxin AdoHcyase PF05221.17 PFH35274.1 - 1.4e-142 474.2 0.0 1.6e-142 474.0 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 PFH35274.1 - 4.4e-79 264.2 2.2 7.2e-79 263.5 2.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 PFH35274.1 - 6.8e-09 35.3 0.3 1.2e-08 34.5 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 PFH35274.1 - 0.00051 19.7 0.5 0.0009 18.8 0.5 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 PFH35274.1 - 0.00068 19.7 0.3 0.0017 18.4 0.2 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 PFH35274.1 - 0.0012 19.3 0.4 0.0027 18.1 0.4 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 PFH35274.1 - 0.0016 17.7 2.4 0.0083 15.4 2.4 2.1 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 PFH35274.1 - 0.013 15.7 2.0 0.045 14.0 0.9 2.4 2 1 0 2 2 2 0 TrkA-N domain ELFV_dehydrog PF00208.21 PFH35274.1 - 0.021 14.5 0.2 0.041 13.6 0.2 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox_2 PF07992.14 PFH35274.1 - 0.029 13.6 0.1 0.045 13.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 PFH35274.1 - 0.13 12.1 0.7 0.24 11.3 0.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAHP_snth_FXD PF18152.1 PFH35274.1 - 0.17 11.7 1.4 0.62 9.9 0.0 2.3 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain AlaDh_PNT_C PF01262.21 PFH35274.1 - 0.69 9.2 5.5 1.7 7.9 5.5 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CLZ PF16526.5 PFH35275.1 - 0.01 16.2 2.7 0.01 16.2 2.7 13.7 10 5 5 15 15 15 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KxDL PF10241.9 PFH35275.1 - 0.056 13.7 0.4 0.056 13.7 0.4 13.3 5 4 11 17 17 17 0 Uncharacterized conserved protein BRI3BP PF14965.6 PFH35275.1 - 4.3 6.8 4.8 40 3.6 0.3 3.7 4 0 0 4 4 4 0 Negative regulator of p53/TP53 EPL1 PF10513.9 PFH35279.1 - 0.029 14.7 0.0 0.084 13.3 0.0 1.7 1 0 0 1 1 1 0 Enhancer of polycomb-like L51_S25_CI-B8 PF05047.16 PFH35281.1 - 0.053 13.4 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Sin3_corepress PF08295.12 PFH35282.1 - 0.046 13.8 2.0 0.14 12.2 2.0 1.8 1 0 0 1 1 1 0 Sin3 family co-repressor NAGLU_C PF12972.7 PFH35282.1 - 0.054 13.0 1.8 0.12 11.9 0.2 2.1 1 1 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain BRE1 PF08647.11 PFH35282.1 - 0.78 9.8 13.7 0.52 10.4 8.6 3.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Nop52 PF05997.12 PFH35283.1 - 3.1e-36 125.2 0.1 4.8e-36 124.6 0.1 1.3 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Sec66 PF09802.9 PFH35284.1 - 5.2e-09 35.9 6.6 9e-09 35.2 6.6 1.4 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 MCU PF04678.13 PFH35284.1 - 0.12 12.4 3.5 0.21 11.7 3.5 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Pkinase PF00069.25 PFH35285.1 - 3e-77 259.5 0.0 4.8e-77 258.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35285.1 - 2.3e-35 122.1 0.0 3.7e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 PFH35285.1 - 1.3e-27 93.2 8.4 4.6e-07 28.9 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PFH35285.1 - 3.8e-27 91.9 2.4 3.3e-07 29.7 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 PFH35285.1 - 5.3e-26 90.9 1.6 6.4e-14 52.2 0.6 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PFH35285.1 - 1.3e-22 79.4 7.8 2.9e-10 39.8 1.4 3.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PFH35285.1 - 3.2e-21 73.8 8.1 2.2e-07 30.0 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 PFH35285.1 - 1.1e-07 32.0 0.7 0.00043 20.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PFH35285.1 - 4.5e-06 26.6 1.0 0.08 12.9 0.0 2.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PFH35285.1 - 4.2e-05 23.8 1.6 0.13 12.6 0.0 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.23 PFH35285.1 - 0.018 15.0 0.0 0.11 12.4 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF1103 PF06513.11 PFH35285.1 - 0.032 13.9 0.8 0.056 13.0 0.8 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) Kdo PF06293.14 PFH35285.1 - 0.15 11.4 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PqiA PF04403.13 PFH35286.1 - 0.00096 19.0 1.1 0.0019 18.0 1.1 1.4 1 1 0 1 1 1 1 Paraquat-inducible protein A PqiA PF04403.13 PFH35287.1 - 1e-05 25.4 17.7 0.00045 20.1 0.1 3.5 3 1 0 3 3 3 2 Paraquat-inducible protein A COX17 PF05051.13 PFH35288.1 - 0.17 12.3 6.2 17 5.9 0.1 3.7 4 0 0 4 4 4 0 Cytochrome C oxidase copper chaperone (COX17) JmjC PF02373.22 PFH35289.1 - 1.2e-10 41.8 0.0 0.00011 22.6 0.0 2.4 2 0 0 2 2 2 2 JmjC domain, hydroxylase Cupin_8 PF13621.6 PFH35289.1 - 3.6e-08 33.4 0.0 4.6e-05 23.3 0.0 2.6 2 1 0 2 2 2 2 Cupin-like domain Phosphodiest PF01663.22 PFH35290.1 - 0.17 11.5 0.1 0.53 9.8 0.1 1.7 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase CutA1 PF03091.15 PFH35291.1 - 8e-37 125.1 0.1 1.2e-36 124.5 0.1 1.3 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein PspB PF06667.12 PFH35292.1 - 0.0089 16.1 1.3 0.55 10.3 0.0 2.6 2 0 0 2 2 2 2 Phage shock protein B DUF4239 PF14023.6 PFH35292.1 - 0.021 14.6 3.0 0.027 14.2 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Nbl1_Borealin_N PF10444.9 PFH35292.1 - 0.89 9.2 7.3 1.9 8.2 0.6 2.9 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal ADK PF00406.22 PFH35293.1 - 2e-56 190.3 0.0 2.4e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PFH35293.1 - 2.5e-25 89.5 0.2 4.7e-25 88.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 PFH35293.1 - 2.6e-14 52.9 0.1 6.6e-14 51.6 0.1 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 PFH35293.1 - 4.7e-06 26.8 0.0 8.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 PFH35293.1 - 0.00034 20.9 0.1 1 9.6 0.0 2.3 1 1 0 2 2 2 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 PFH35293.1 - 0.0022 18.5 0.1 0.0085 16.6 0.1 2.0 2 1 0 2 2 2 1 AAA domain DAP3 PF10236.9 PFH35293.1 - 0.12 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AMP-binding PF00501.28 PFH35294.1 - 3.1e-18 65.6 0.2 4.4e-08 32.1 0.1 3.9 3 1 0 3 3 3 3 AMP-binding enzyme Spatacsin_C PF14649.6 PFH35295.1 - 3.4e-07 29.7 0.0 5.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Spatacsin C-terminus Spatacsin_C PF14649.6 PFH35296.1 - 5.7e-13 48.6 0.1 1.3e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Spatacsin C-terminus ECR1_N PF14382.6 PFH35297.1 - 1e-13 50.8 0.3 2e-13 49.9 0.3 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 PFH35297.1 - 1.2e-08 35.2 0.0 3.4e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 KH domain DUF1082 PF06449.11 PFH35297.1 - 0.12 12.2 0.3 0.56 10.1 0.1 2.0 1 1 1 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) RRM_1 PF00076.22 PFH35298.1 - 3.4e-74 244.6 0.3 5.2e-21 74.2 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 PFH35298.1 - 2.4e-27 94.9 1.4 1.9e-26 92.1 1.7 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 PFH35298.1 - 6.5e-05 22.7 0.0 1.1 9.1 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 PFH35298.1 - 0.00013 22.0 0.1 0.56 10.4 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 PFH35298.1 - 0.00074 19.5 0.1 2.2 8.4 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif PDEase_I PF00233.19 PFH35300.1 - 1e-72 244.8 0.1 2e-72 243.8 0.1 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 PFH35300.1 - 0.0048 17.1 0.0 0.02 15.1 0.0 2.0 2 0 0 2 2 2 1 HD domain Zea_mays_MuDR PF05928.11 PFH35300.1 - 0.049 13.3 0.2 0.091 12.4 0.2 1.3 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) ABM PF03992.16 PFH35302.1 - 0.0046 17.0 0.0 0.0072 16.4 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase NUDE_C PF04880.13 PFH35302.1 - 1.1 9.7 4.6 1.4 9.4 4.6 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region ER_lumen_recept PF00810.18 PFH35303.1 - 3.3e-26 92.9 7.8 3.3e-26 92.9 7.8 2.0 2 1 0 2 2 2 1 ER lumen protein retaining receptor NAD4L PF06235.11 PFH35303.1 - 6.9 6.7 12.0 4.4 7.4 4.2 2.9 2 1 0 2 2 2 0 NADH dehydrogenase subunit 4L (NAD4L) DUF3752 PF12572.8 PFH35304.1 - 1.4e-05 25.6 23.8 1.4e-05 25.6 23.8 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3752) SR-25 PF10500.9 PFH35304.1 - 0.0004 20.1 41.1 0.0004 20.1 41.1 2.5 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Zip PF02535.22 PFH35304.1 - 0.86 8.8 10.0 1.5 8.0 10.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter FancD2 PF14631.6 PFH35304.1 - 4.1 4.7 13.6 5.5 4.2 13.6 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RAP1 PF07218.11 PFH35305.1 - 0.47 8.7 4.5 0.53 8.5 4.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RRM_1 PF00076.22 PFH35306.1 - 1.1e-17 63.5 0.0 1.9e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 PFH35306.1 - 1.1e-10 41.6 0.0 2.4e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 SPOC domain RRM_occluded PF16842.5 PFH35306.1 - 0.028 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif PA PF02225.22 PFH35307.1 - 2e-08 34.2 0.0 1.3e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 PA domain zf-ribbon_3 PF13248.6 PFH35308.1 - 0.41 10.1 3.8 9 5.9 0.2 2.8 1 1 1 2 2 2 0 zinc-ribbon domain zf-RING_5 PF14634.6 PFH35308.1 - 0.59 10.1 2.5 1.8 8.6 2.5 1.9 1 0 0 1 1 1 0 zinc-RING finger domain DUF3552 PF12072.8 PFH35308.1 - 2.7 7.4 11.9 5.4 6.4 11.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF45 PF01863.17 PFH35308.1 - 3.9 7.5 6.4 9.1 6.3 6.4 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF45 CBM_14 PF01607.24 PFH35309.1 - 0.3 11.3 0.8 1.6 8.9 0.1 2.6 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain cEGF PF12662.7 PFH35309.1 - 0.96 9.4 8.9 38 4.3 0.1 4.3 4 0 0 4 4 4 0 Complement Clr-like EGF-like DnaJ PF00226.31 PFH35310.1 - 0.00055 20.0 0.6 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain TFIIS_M PF07500.14 PFH35311.1 - 6.3e-17 62.1 1.2 1.2e-16 61.1 1.2 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain mRNA_triPase PF02940.15 PFH35312.1 - 9.3e-16 58.2 0.0 2.2e-15 57.0 0.0 1.6 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain zf-CCCH_4 PF18044.1 PFH35313.1 - 0.006 16.4 9.6 1.8 8.5 0.1 4.0 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 PFH35313.1 - 0.0075 16.2 0.3 0.0075 16.2 0.3 3.9 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PFH35313.1 - 0.0085 16.1 19.1 0.12 12.5 0.5 3.8 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH_3 PF15663.5 PFH35313.1 - 0.24 11.6 9.6 0.02 15.1 2.5 2.7 3 0 0 3 3 3 0 Zinc-finger containing family Cytochrom_B_C PF00032.17 PFH35315.1 - 1.9e-13 50.6 3.4 1.9e-13 50.6 3.4 1.5 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD GYF PF02213.16 PFH35316.1 - 4.3e-12 45.5 0.1 8.7e-12 44.5 0.1 1.5 1 0 0 1 1 1 1 GYF domain IQ PF00612.27 PFH35316.1 - 0.0019 17.9 0.7 0.0058 16.3 0.7 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif GHL13 PF14883.6 PFH35316.1 - 0.13 11.3 5.9 0.24 10.4 5.9 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 Sporozoite_P67 PF05642.11 PFH35316.1 - 2.7 6.0 12.8 1.3 7.1 8.0 2.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen MMR_HSR1_C PF08438.10 PFH35317.1 - 8.6e-32 110.0 0.1 1.3e-31 109.5 0.1 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 PFH35317.1 - 1.9e-20 73.0 0.0 4.6e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PFH35317.1 - 3.5e-09 36.4 1.0 2.1e-06 27.4 0.2 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B ATP_bind_1 PF03029.17 PFH35317.1 - 0.02 14.7 1.1 0.92 9.2 0.0 2.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TGS PF02824.21 PFH35317.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 TGS domain GTP_EFTU PF00009.27 PFH35317.1 - 0.081 12.4 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain E7R PF17467.2 PFH35317.1 - 0.12 12.6 0.0 0.35 11.0 0.0 1.7 2 0 0 2 2 2 0 Viral Protein E7 HTH_9 PF08221.11 PFH35319.1 - 5.3e-05 23.2 1.2 0.04 14.0 0.1 2.7 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 PFH35319.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.6 1 1 0 1 1 1 0 RNA polymerase III subunit RPC82 RRM_1 PF00076.22 PFH35320.1 - 1.4e-43 146.6 0.0 5.5e-21 74.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PFH35320.1 - 2.1e-05 24.1 0.0 0.0041 16.7 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH35320.1 - 0.0012 18.9 0.0 0.036 14.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 PFH35320.1 - 0.022 14.4 0.1 2.1 8.1 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 PFH35320.1 - 0.18 11.8 0.0 1.7 8.7 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF819 PF05684.12 PFH35321.1 - 2.1e-23 83.0 18.1 2.1e-13 50.1 1.2 3.5 3 1 0 3 3 3 3 Protein of unknown function (DUF819) Myosin_head PF00063.21 PFH35322.1 - 0.32 9.2 0.0 0.47 8.6 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) NRBF2 PF08961.10 PFH35322.1 - 5.8 6.5 10.9 11 5.5 6.8 2.5 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator IMCp PF12314.8 PFH35323.1 - 2.5e-27 95.0 47.7 4e-26 91.1 31.5 2.2 1 1 1 2 2 2 2 Inner membrane complex protein IMCp PF12314.8 PFH35324.1 - 7.6e-21 74.2 37.9 7.6e-15 55.0 16.8 2.1 1 1 1 2 2 2 2 Inner membrane complex protein GT-D PF08759.11 PFH35324.1 - 0.13 11.9 0.3 0.18 11.5 0.3 1.1 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold DUF572 PF04502.13 PFH35325.1 - 0.4 10.3 2.0 1.4 8.4 2.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF572) ABA_WDS PF02496.16 PFH35325.1 - 3.4 8.2 6.6 0.34 11.4 1.7 1.9 2 0 0 2 2 2 0 ABA/WDS induced protein polyprenyl_synt PF00348.17 PFH35326.1 - 1e-64 218.0 0.0 2.5e-32 112.0 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Pkinase PF00069.25 PFH35327.1 - 6.2e-41 140.5 0.0 1.1e-40 139.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35327.1 - 1.9e-14 53.6 0.0 4.2e-14 52.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 PFH35328.1 - 0.048 13.6 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 F-box-like DUF3458_C PF17432.2 PFH35329.1 - 9.9e-86 288.0 8.2 1.6e-85 287.3 8.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 PFH35329.1 - 3.3e-51 173.9 0.0 5.1e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 PFH35329.1 - 1.4e-25 89.5 0.7 3.4e-25 88.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 PFH35329.1 - 1e-08 35.6 0.0 1.7e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 PFH35329.1 - 0.007 16.7 0.4 0.033 14.6 0.4 2.1 1 1 0 1 1 1 1 M61 glycyl aminopeptidase SBP_bac_5 PF00496.22 PFH35329.1 - 0.038 12.9 0.0 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle DUF3458_C PF17432.2 PFH35330.1 - 1.1e-99 333.8 5.6 1.6e-99 333.3 5.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 PFH35330.1 - 2.5e-53 180.9 0.1 3.8e-53 180.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 PFH35330.1 - 1.1e-27 96.3 0.2 3.5e-27 94.7 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 PFH35330.1 - 9.1e-12 45.5 0.0 1.9e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 PFH35330.1 - 0.03 14.7 0.1 0.16 12.4 0.1 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DUF1908 PF08926.11 PFH35331.1 - 1.4 7.9 6.3 1.9 7.5 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) PA28_beta PF02252.18 PFH35332.1 - 2.9e-48 163.2 0.8 5e-48 162.5 0.8 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 PFH35332.1 - 0.072 13.1 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit SAG PF04092.13 PFH35336.1 - 3.4e-05 24.6 0.3 4.5e-05 24.2 0.3 1.1 1 0 0 1 1 1 1 SRS domain DUF2613 PF11021.8 PFH35336.1 - 0.5 10.5 2.2 4.2 7.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) SAG PF04092.13 PFH35337.1 - 4e-11 43.8 0.9 5.2e-11 43.4 0.9 1.1 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH35338.1 - 4.5e-05 24.2 2.3 7.3e-05 23.6 2.3 1.3 1 0 0 1 1 1 1 SRS domain DHHC PF01529.20 PFH35339.1 - 4.8e-37 127.0 9.0 4.8e-37 127.0 9.0 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase SAG PF04092.13 PFH35340.1 - 2.1e-23 83.6 15.9 3.1e-13 50.7 9.0 2.4 2 0 0 2 2 2 2 SRS domain DUF2541 PF10807.8 PFH35340.1 - 0.074 13.1 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2541) FIT1_2 PF17357.2 PFH35340.1 - 2.4 8.3 6.9 1.1 9.3 0.7 2.9 3 0 0 3 3 3 0 Facilitor Of iron transport 1 and 2 SAG PF04092.13 PFH35341.1 - 9.5e-22 78.2 18.2 2.6e-12 47.7 5.3 2.3 2 0 0 2 2 2 2 SRS domain Mucin PF01456.17 PFH35341.1 - 0.00069 19.6 1.5 0.00069 19.6 1.5 2.2 2 1 0 2 2 2 1 Mucin-like glycoprotein SAG PF04092.13 PFH35342.1 - 9.8e-17 62.0 16.5 2.5e-08 34.8 3.9 2.5 2 1 0 2 2 2 2 SRS domain SAG PF04092.13 PFH35343.1 - 2.4e-17 63.9 19.3 9.5e-09 36.1 3.5 2.3 2 0 0 2 2 2 2 SRS domain DUF1935 PF09149.10 PFH35343.1 - 0.17 12.3 1.5 5.8 7.4 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1935) LMF1 PF06762.14 PFH35344.1 - 3.9e-67 227.3 21.2 5.6e-42 144.4 13.4 3.1 2 1 1 3 3 3 2 Lipase maturation factor DoxX PF07681.12 PFH35344.1 - 7.8e-07 29.6 3.0 7.8e-07 29.6 3.0 3.4 2 1 1 3 3 3 1 DoxX IBN_N PF03810.19 PFH35350.1 - 1.7e-05 24.6 0.4 1.7e-05 24.6 0.4 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain CSTF_C PF14304.6 PFH35350.1 - 0.67 9.6 5.3 1.1 8.9 1.4 2.7 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal Kinase-like PF14531.6 PFH35351.1 - 6.7e-51 173.3 0.2 2.9e-40 138.4 0.1 2.1 1 1 1 2 2 2 2 Kinase-like Pkinase PF00069.25 PFH35351.1 - 1.4e-16 60.6 0.0 1.8e-14 53.8 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35351.1 - 1.8e-07 30.7 0.1 8.1e-07 28.6 0.1 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 PFH35351.1 - 6.8e-05 22.9 0.1 0.00014 21.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PFH35351.1 - 0.062 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family E3_UFM1_ligase PF09743.9 PFH35352.1 - 2.4e-78 263.5 0.0 3.4e-78 263.0 0.0 1.2 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 FeoC PF09012.10 PFH35352.1 - 8.2e-05 22.6 0.2 3.6 7.7 0.0 4.0 4 0 0 4 4 4 3 FeoC like transcriptional regulator HTH_9 PF08221.11 PFH35352.1 - 0.1 12.7 0.1 0.69 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain POTRA_TamA_1 PF17243.2 PFH35352.1 - 3.8 7.7 6.8 1 9.5 0.5 3.4 5 0 0 5 5 5 0 POTRA domain TamA domain 1 FAM91_N PF14647.6 PFH35353.1 - 0.0023 17.2 1.4 0.0054 16.1 1.4 1.6 1 0 0 1 1 1 1 FAM91 N-terminus ATPase PF06745.13 PFH35353.1 - 1.6 8.0 6.2 3.3 7.0 6.2 1.5 1 0 0 1 1 1 0 KaiC Phage_holin_6_1 PF09682.10 PFH35353.1 - 2.8 8.4 7.0 7.7 7.0 0.1 2.7 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) PMC2NT PF08066.12 PFH35353.1 - 3 8.6 7.3 3.7 8.3 0.5 3.6 4 0 0 4 4 4 0 PMC2NT (NUC016) domain Methyltr_RsmB-F PF01189.17 PFH35354.1 - 1.3e-24 86.9 0.1 1.3e-18 67.4 0.0 2.3 1 1 1 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 PFH35354.1 - 7.3e-05 22.9 0.0 0.0003 20.9 0.0 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase OxoGdeHyase_C PF16870.5 PFH35354.1 - 0.074 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal PCMT PF01135.19 PFH35354.1 - 0.085 12.6 0.0 0.39 10.4 0.0 2.0 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4551 PF15087.6 PFH35354.1 - 5 5.8 5.0 7.8 5.2 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SlyX PF04102.12 PFH35355.1 - 0.028 15.0 0.9 0.13 12.9 0.9 2.2 1 0 0 1 1 1 0 SlyX DUF4715 PF15835.5 PFH35355.1 - 0.1 12.7 4.5 0.54 10.3 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4715) ER_lumen_recept PF00810.18 PFH35356.1 - 1.1e-36 126.9 3.8 1.1e-36 126.9 3.8 1.8 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 PFH35356.1 - 0.05 13.4 0.3 0.05 13.4 0.3 3.3 2 1 0 2 2 2 0 PQ loop repeat Syntaxin-18_N PF10496.9 PFH35357.1 - 9.5 6.6 7.6 7.6 6.9 3.6 2.7 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Metallophos PF00149.28 PFH35358.1 - 3.2e-33 115.9 0.2 4.5e-33 115.5 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PFH35358.1 - 0.035 14.3 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain HscB_4_cys PF18256.1 PFH35358.1 - 0.081 12.8 0.0 9.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Glyco_hydro_65N PF03636.15 PFH35358.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain AP2 PF00847.20 PFH35359.1 - 0.011 15.9 2.0 0.011 15.9 2.0 2.3 2 0 0 2 2 2 0 AP2 domain IF3_C PF00707.22 PFH35360.1 - 4.9e-19 68.1 0.0 9.3e-19 67.2 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Ribosomal_L4 PF00573.22 PFH35360.1 - 0.02 14.6 1.1 0.042 13.5 1.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family mIF3 PF14877.6 PFH35360.1 - 0.14 11.8 0.3 0.22 11.1 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor PP2C PF00481.21 PFH35361.1 - 8e-54 183.0 0.3 1.1e-53 182.6 0.3 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PFH35361.1 - 0.00029 20.6 0.1 0.00074 19.2 0.1 1.8 1 0 0 1 1 1 1 Protein phosphatase 2C zf-HC5HC2H_2 PF13832.6 PFH35362.1 - 8.9e-18 64.5 29.8 8e-13 48.5 4.2 4.2 4 0 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PFH35362.1 - 8e-15 54.9 33.4 7.5e-09 35.7 6.9 5.0 4 0 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 PFH35362.1 - 1.3e-05 25.0 19.8 0.00013 21.7 1.6 7.8 9 0 0 9 9 9 2 PHD-finger zf-PHD-like PF15446.6 PFH35362.1 - 0.011 15.3 0.2 0.011 15.3 0.2 4.3 4 0 0 4 4 4 0 PHD/FYVE-zinc-finger like domain Clathrin PF00637.20 PFH35363.1 - 5.8e-07 29.5 0.0 0.0002 21.2 0.0 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS CPSF_A PF03178.15 PFH35364.1 - 1.4e-24 87.0 0.0 2.1e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 CPSF A subunit region DHHC PF01529.20 PFH35365.1 - 8.4e-38 129.5 12.1 1.6e-37 128.6 12.1 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Trypan_PARP PF05887.11 PFH35365.1 - 0.15 12.0 6.8 0.25 11.3 6.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HECT PF00632.25 PFH35367.1 - 2.3e-67 227.7 0.0 3.1e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 PFH35367.1 - 6e-33 113.2 16.1 6.8e-10 39.4 0.0 8.9 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH35367.1 - 4.1e-25 87.0 27.2 2.2e-08 33.7 0.0 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat LRR_4 PF12799.7 PFH35368.1 - 1.5e-10 41.2 3.6 6.6e-05 23.2 0.0 3.9 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH35368.1 - 5.9e-10 38.8 5.4 1.7e-06 27.7 0.0 4.5 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 PFH35368.1 - 0.00099 19.0 3.8 18 5.7 0.2 5.1 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 PFH35368.1 - 0.018 15.5 0.7 61 4.8 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_9 PF14580.6 PFH35368.1 - 0.11 12.0 0.2 0.38 10.2 0.2 2.0 2 0 0 2 2 2 0 Leucine-rich repeat ISN1 PF06437.11 PFH35370.1 - 1.8e-81 274.2 0.0 2.3e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Glyco_transf_5 PF08323.11 PFH35371.1 - 8e-33 114.1 0.0 1.5e-32 113.3 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain AMPK1_CBM PF16561.5 PFH35371.1 - 5.4e-15 55.4 0.0 1.2e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Glycos_transf_1 PF00534.20 PFH35371.1 - 4.2e-12 45.9 0.0 7.6e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PFH35371.1 - 2.3e-06 28.1 0.0 5.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Metallophos PF00149.28 PFH35372.1 - 3.2e-13 50.6 0.1 5.9e-13 49.8 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PFH35372.1 - 2.5e-07 31.1 0.1 5.9e-07 29.8 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Lipase_GDSL_2 PF13472.6 PFH35372.1 - 0.016 15.6 0.0 0.041 14.3 0.0 1.7 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PFH35372.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Metallophos_3 PF14582.6 PFH35372.1 - 0.15 11.4 0.0 0.38 10.1 0.0 1.6 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Dabb PF07876.12 PFH35373.1 - 1.4e-20 73.7 0.4 1.5e-20 73.6 0.4 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain eIF2A PF08662.11 PFH35374.1 - 6.1e-29 101.3 3.2 7.2e-23 81.5 0.4 3.0 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 PFH35374.1 - 2.9e-06 27.0 0.0 1.7e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 PFH35374.1 - 0.0035 18.1 0.2 19 6.4 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat SL4P PF17618.2 PFH35374.1 - 0.014 15.4 0.0 0.43 10.7 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein ANAPC4_WD40 PF12894.7 PFH35374.1 - 0.021 15.1 0.1 19 5.6 0.0 4.3 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain AAA_23 PF13476.6 PFH35374.1 - 0.34 11.4 5.3 1.4 9.4 4.2 2.5 2 0 0 2 2 2 0 AAA domain PAC3 PF10178.9 PFH35375.1 - 2.5e-12 46.7 0.0 6.1e-12 45.5 0.0 1.6 2 0 0 2 2 2 1 Proteasome assembly chaperone 3 HAD PF12710.7 PFH35377.1 - 1.2e-22 81.2 10.5 1e-18 68.4 0.1 3.7 3 1 0 4 4 4 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PFH35377.1 - 6.2e-16 59.3 0.2 6.2e-16 59.3 0.2 3.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PFH35377.1 - 2.8e-07 30.5 0.5 4.9e-07 29.7 0.1 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 PFH35377.1 - 5.1e-06 26.0 0.0 7.4e-05 22.2 0.0 2.2 1 1 0 1 1 1 1 Putative Phosphatase ACT_6 PF13740.6 PFH35377.1 - 0.001 19.0 0.0 1.8 8.6 0.0 4.1 4 0 0 4 4 4 1 ACT domain HAD_2 PF13419.6 PFH35377.1 - 0.0025 17.9 0.0 0.017 15.2 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase His_Phos_1 PF00300.22 PFH35378.1 - 1.1e-19 70.9 2.6 4.8e-12 46.0 0.3 2.7 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Pex14_N PF04695.13 PFH35378.1 - 0.0015 19.2 2.5 0.0023 18.6 0.6 2.2 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sedlin_N PF04628.13 PFH35379.1 - 1.4e-39 135.2 0.0 1.6e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 PFH35379.1 - 1.5e-05 24.9 0.0 5.1e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Sybindin-like family NFACT-R_1 PF05670.13 PFH35380.1 - 3.6e-11 43.7 0.0 6.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 PFH35380.1 - 1e-06 28.9 0.0 2.4e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain CPW_WPC PF09717.10 PFH35381.1 - 0.18 12.8 8.7 0.31 12.1 0.0 4.4 4 2 0 4 4 4 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Ocnus PF05005.15 PFH35382.1 - 2.8e-29 101.4 0.1 4.2e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Suf PF05843.14 PFH35382.1 - 0.039 13.9 1.1 0.049 13.6 1.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Caskin-tail PF16632.5 PFH35382.1 - 0.55 10.7 4.0 0.44 11.0 0.5 2.3 1 1 1 2 2 2 0 C-terminal region of Caskin Chromo PF00385.24 PFH35383.1 - 0.0047 16.8 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.25 PFH35384.1 - 9.2e-20 71.1 0.0 4.1e-17 62.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35384.1 - 2.5e-07 30.3 0.0 5.8e-06 25.8 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Inositol_P PF00459.25 PFH35385.1 - 2.4e-68 230.6 0.0 3.5e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Baculo_F PF12259.8 PFH35385.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Baculovirus F protein PAN_1 PF00024.26 PFH35386.1 - 1.6e-24 85.6 33.2 2e-05 24.5 0.2 6.9 6 1 0 6 6 6 6 PAN domain PAN_4 PF14295.6 PFH35386.1 - 3.1e-17 62.2 33.7 0.00035 20.4 0.9 6.8 7 0 0 7 7 7 5 PAN domain Ribosomal_S18 PF01084.20 PFH35387.1 - 3e-15 56.2 0.0 8.4e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S18 Dynein_light PF01221.18 PFH35388.1 - 4.2e-42 142.4 0.5 4.6e-42 142.2 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Coprogen_oxidas PF01218.18 PFH35389.1 - 7.1e-83 277.7 0.6 8.6e-83 277.5 0.6 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase TPR_2 PF07719.17 PFH35391.1 - 1.5e-08 34.1 3.9 0.0009 19.2 0.2 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PFH35391.1 - 9.6e-05 22.0 0.4 0.0077 16.0 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 PFH35391.1 - 0.052 13.8 0.1 0.052 13.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PFH35391.1 - 0.15 12.4 0.6 3.8 8.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 PFH35391.1 - 0.16 12.1 1.6 0.44 10.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PFH35391.1 - 1 9.9 7.6 17 6.0 1.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 PFH35391.1 - 1.2 10.0 7.3 4.3 8.2 0.4 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_S10 PF00338.22 PFH35393.1 - 6.8e-29 100.0 0.1 7.8e-29 99.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e MORN PF02493.20 PFH35394.1 - 1.4e-30 103.3 53.4 2.9e-05 23.7 1.7 11.4 11 0 0 11 11 11 10 MORN repeat Cadherin-like PF12733.7 PFH35394.1 - 5.8e-05 23.5 0.0 0.12 12.9 0.0 3.3 3 0 0 3 3 3 2 Cadherin-like beta sandwich domain Zeta_toxin PF06414.12 PFH35397.1 - 0.0034 16.7 0.0 0.0089 15.3 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 PFH35397.1 - 0.013 16.1 0.0 0.035 14.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PFH35397.1 - 0.031 14.6 0.0 0.099 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 PFH35397.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 PFH35397.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 PFH35397.1 - 0.15 12.3 0.6 0.78 9.9 0.2 2.3 2 0 0 2 2 2 0 AAA domain GLTP PF08718.11 PFH35398.1 - 2.9e-31 108.8 0.0 3.6e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) CKS PF01111.19 PFH35399.1 - 1.2e-12 47.9 3.5 1.2e-12 47.9 3.5 1.4 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit TRM13 PF05206.14 PFH35400.1 - 9.1e-24 84.4 1.1 3.5e-18 66.1 0.0 3.9 2 2 0 2 2 2 2 Methyltransferase TRM13 ubiquitin PF00240.23 PFH35400.1 - 4e-23 80.9 0.5 4e-23 80.9 0.5 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 PFH35400.1 - 1.2e-10 41.0 1.0 2.3e-10 40.1 0.4 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like zf-U11-48K PF05253.12 PFH35400.1 - 0.00062 19.6 0.7 0.0016 18.3 0.7 1.8 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger tRNA_bind PF01588.20 PFH35401.1 - 3.3e-25 88.0 0.0 5.8e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 PFH35401.1 - 2.8e-06 27.2 0.1 6.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PFH35401.1 - 0.00014 22.0 0.1 0.00029 21.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PFH35401.1 - 0.0018 18.4 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain START PF01852.19 PFH35402.1 - 7.3e-10 38.6 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 START domain His_Phos_1 PF00300.22 PFH35403.1 - 2.8e-37 128.3 0.0 5.6e-31 107.8 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Carb_anhydrase PF00194.21 PFH35404.1 - 3.3e-22 79.3 5.4 4.4e-14 52.6 0.1 3.0 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase DUF3843 PF12954.7 PFH35404.1 - 0.012 14.6 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) Phos_pyr_kin PF08543.12 PFH35405.1 - 4.8e-08 32.7 0.0 0.00015 21.2 0.0 2.8 3 0 0 3 3 3 2 Phosphomethylpyrimidine kinase PfkB PF00294.24 PFH35405.1 - 0.00021 20.7 0.2 1.5 8.0 0.0 3.1 3 0 0 3 3 3 2 pfkB family carbohydrate kinase LCE PF14672.6 PFH35407.1 - 2.3 8.9 12.3 2 9.1 4.3 2.3 2 0 0 2 2 2 0 Late cornified envelope Kinesin PF00225.23 PFH35408.1 - 1.4e-93 313.5 0.1 9.1e-56 189.2 0.0 2.9 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 PFH35408.1 - 1.6e-20 73.6 0.0 4.8e-20 72.0 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding DUF4948 PF16306.5 PFH35408.1 - 0.012 15.5 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4948) Utp12 PF04003.12 PFH35408.1 - 8.5 6.7 7.8 26 5.2 1.7 3.5 3 0 0 3 3 3 0 Dip2/Utp12 Family DUF4366 PF14283.6 PFH35410.1 - 0.12 12.4 0.2 0.19 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) LSM PF01423.22 PFH35411.1 - 2e-13 49.8 0.0 2.6e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 PFH35411.1 - 0.076 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Hfq protein MORN PF02493.20 PFH35412.1 - 6.8e-45 148.3 55.8 2.5e-06 27.1 0.6 9.9 11 0 0 11 11 11 8 MORN repeat DUF3048_C PF17479.2 PFH35412.1 - 0.13 12.6 4.4 1.5 9.3 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain Tudor_2 PF18104.1 PFH35412.1 - 3.4 7.4 5.7 24 4.7 0.1 3.8 4 0 0 4 4 4 0 Jumonji domain-containing protein 2A Tudor domain Coa1 PF08695.10 PFH35413.1 - 0.006 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_L17 PF01196.19 PFH35414.1 - 2.7e-19 69.8 0.0 4.1e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 FUSC PF04632.12 PFH35414.1 - 3.7 6.0 5.5 3.7 5.9 0.4 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family CRAL_TRIO PF00650.20 PFH35415.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 CRAL/TRIO domain AMP-binding PF00501.28 PFH35418.1 - 1.2e-82 277.8 0.2 2.7e-81 273.3 0.2 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Vps53_N PF04100.12 PFH35419.1 - 1.3e-62 212.0 0.0 2.1e-31 109.2 0.2 3.3 2 1 0 2 2 2 2 Vps53-like, N-terminal Zw10 PF06248.13 PFH35419.1 - 0.015 13.9 0.3 0.062 11.9 0.3 1.9 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 DUF4795 PF16043.5 PFH35419.1 - 0.057 13.0 0.1 0.15 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4732 PF15876.5 PFH35419.1 - 0.097 12.8 0.1 5.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4732) MFS_1 PF07690.16 PFH35420.1 - 1e-11 44.4 45.4 8.6e-08 31.5 41.6 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Baculo_PEP_C PF04513.12 PFH35427.1 - 0.16 12.0 10.6 0.12 12.5 2.3 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3037 PF11236.8 PFH35427.1 - 0.31 11.5 15.2 0.21 12.0 0.9 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) DUF4715 PF15835.5 PFH35427.1 - 1.7 8.7 7.0 0.43 10.6 2.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4715) DUF1179 PF06678.11 PFH35427.1 - 2.6 8.1 5.0 5.1 7.1 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) STAT_alpha PF01017.20 PFH35427.1 - 5 7.0 15.4 4.6e+02 0.6 15.4 2.3 1 1 0 1 1 1 0 STAT protein, all-alpha domain ATG16 PF08614.11 PFH35428.1 - 2.4 8.3 59.8 0.97 9.6 20.8 2.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 PFH35428.1 - 9.8 6.7 6.6 38 4.9 0.1 4.1 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TIP49 PF06068.13 PFH35429.1 - 8.8e-161 534.9 0.5 1.1e-160 534.7 0.5 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 PFH35429.1 - 3.7e-19 68.6 0.2 1.2e-18 67.0 0.2 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 PFH35429.1 - 7.7e-12 45.8 0.1 1.5e-08 35.1 0.1 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PFH35429.1 - 4.9e-10 39.4 0.1 1.5e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PFH35429.1 - 1.7e-07 31.6 0.1 0.0059 16.9 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 PFH35429.1 - 7.5e-06 26.0 0.3 0.0019 18.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PFH35429.1 - 1.3e-05 25.6 0.2 0.00013 22.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 PFH35429.1 - 0.00015 21.2 0.2 0.0065 15.9 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 PFH35429.1 - 0.00057 19.6 0.1 0.7 9.6 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 PFH35429.1 - 0.00068 20.0 1.8 0.049 14.0 1.8 2.6 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 PFH35429.1 - 0.0011 18.3 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_28 PF13521.6 PFH35429.1 - 0.0019 18.5 0.0 0.0095 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 PFH35429.1 - 0.0037 17.0 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 PFH35429.1 - 0.0048 16.5 0.0 0.0089 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PFH35429.1 - 0.0067 17.0 0.0 0.018 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 PFH35429.1 - 0.0084 16.1 0.0 5.4 7.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PFH35429.1 - 0.0094 15.5 0.0 0.037 13.5 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 PFH35429.1 - 0.012 14.9 0.1 0.038 13.3 0.1 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 PFH35429.1 - 0.018 15.2 0.0 0.045 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 PFH35429.1 - 0.028 13.6 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 PFH35429.1 - 0.029 14.4 0.5 0.51 10.3 0.1 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 PFH35429.1 - 0.03 14.3 0.0 0.087 12.8 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 PFH35429.1 - 0.038 14.4 0.0 0.23 11.9 0.0 2.4 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 PFH35429.1 - 0.042 13.2 0.1 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_11 PF13086.6 PFH35429.1 - 0.043 13.6 0.1 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PFH35429.1 - 0.046 13.4 0.0 0.79 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 PFH35429.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Parvo_NS1 PF01057.17 PFH35429.1 - 0.053 12.6 0.1 0.097 11.8 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 PFH35429.1 - 0.055 12.9 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.6 PFH35429.1 - 0.062 13.4 0.0 5 7.2 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.6 PFH35429.1 - 0.081 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 PFH35429.1 - 0.093 13.1 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 PFH35429.1 - 0.12 11.8 0.4 4.5 6.6 0.0 2.7 3 0 0 3 3 3 0 Bacterial TniB protein WD40 PF00400.32 PFH35430.1 - 3.6e-15 56.1 4.2 0.039 14.8 0.1 8.5 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH35430.1 - 0.015 15.6 0.0 3.6 8.0 0.0 3.9 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain UL41A PF17591.2 PFH35431.1 - 0.19 11.8 0.1 0.38 10.9 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL41A TFCD_C PF12612.8 PFH35433.1 - 1.8e-07 31.2 0.1 0.00031 20.6 0.0 3.4 3 0 0 3 3 3 2 Tubulin folding cofactor D C terminal Cnd1 PF12717.7 PFH35433.1 - 0.0026 17.8 0.8 0.19 11.8 0.1 3.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PFH35433.1 - 0.017 15.6 0.0 0.017 15.6 0.0 8.4 8 0 0 8 8 8 0 HEAT-like repeat Bclt PF15318.6 PFH35433.1 - 0.11 12.3 1.0 0.45 10.3 0.1 2.6 2 0 0 2 2 2 0 Putative Bcl-2 like protein of testis TAF6_C PF07571.13 PFH35433.1 - 0.24 11.8 5.3 5.6 7.4 0.1 4.1 5 0 0 5 5 5 0 TAF6 C-terminal HEAT repeat domain FoP_duplication PF13865.6 PFH35434.1 - 2.6e-18 66.3 11.9 2.6e-18 66.3 11.9 3.8 1 1 3 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 YbfN PF13982.6 PFH35435.1 - 0.00027 21.2 1.6 0.0027 17.9 0.1 2.1 1 1 1 2 2 2 1 YbfN-like lipoprotein ApoLp-III PF07464.11 PFH35435.1 - 0.0015 18.7 1.9 0.0019 18.3 1.9 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) GAS PF13851.6 PFH35435.1 - 0.018 14.4 10.2 0.027 13.8 10.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 PFH35435.1 - 0.05 13.4 7.3 0.059 13.2 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PriA_C PF18074.1 PFH35435.1 - 0.14 13.0 0.7 0.28 12.0 0.4 1.7 1 1 1 2 2 2 0 Primosomal protein N C-terminal domain TMPIT PF07851.13 PFH35435.1 - 0.22 10.8 4.6 0.24 10.6 4.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein APG6_N PF17675.1 PFH35435.1 - 0.23 12.0 10.0 0.25 11.9 9.1 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region CENP-H PF05837.12 PFH35435.1 - 0.74 10.2 9.3 1.7 9.1 9.3 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) CCDC-167 PF15188.6 PFH35435.1 - 1.6 9.1 9.2 11 6.5 5.7 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 IQ PF00612.27 PFH35437.1 - 9.4e-10 37.4 32.3 0.00042 19.9 2.3 5.2 4 0 0 4 4 4 4 IQ calmodulin-binding motif WD40 PF00400.32 PFH35438.1 - 5.1e-07 30.3 0.8 1 10.3 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Stress-antifung PF01657.17 PFH35439.1 - 0.047 14.3 0.5 0.061 14.0 0.5 1.3 1 1 0 1 1 1 0 Salt stress response/antifungal CHCH PF06747.13 PFH35439.1 - 0.85 9.8 4.0 14 6.0 0.6 2.2 2 0 0 2 2 2 0 CHCH domain EF-hand_6 PF13405.6 PFH35440.1 - 0.0033 17.2 0.0 0.0077 16.1 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain DUF2344 PF10105.9 PFH35440.1 - 0.0042 16.9 0.1 0.21 11.4 0.0 2.6 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2344) Cpn60_TCP1 PF00118.24 PFH35442.1 - 8.1e-155 516.2 1.8 9.3e-155 516.0 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PPTA PF01239.22 PFH35443.1 - 6.2e-18 63.9 18.0 1.1e-07 31.3 1.1 4.9 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat RNA_pol_Rpb2_6 PF00562.28 PFH35445.1 - 1.3e-113 380.0 0.0 2.3e-113 379.2 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 PFH35445.1 - 4.1e-28 98.3 0.0 6.6e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 PFH35445.1 - 6.3e-26 90.4 0.0 1.3e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 PFH35445.1 - 3e-19 69.2 0.0 5.7e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 PFH35445.1 - 0.00092 19.2 0.0 0.0027 17.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain Rpr2 PF04032.16 PFH35445.1 - 0.11 12.8 1.0 0.3 11.4 1.0 1.7 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Acyltransferase PF01553.21 PFH35446.1 - 1.8e-20 73.0 0.0 2.7e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Metallophos PF00149.28 PFH35447.1 - 1.1e-09 39.0 0.0 0.00046 20.7 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PFH35447.1 - 0.056 13.6 0.0 1.1 9.4 0.0 2.6 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain CAF-1_p60_C PF15512.6 PFH35447.1 - 0.99 9.9 6.9 0.38 11.2 2.2 2.2 2 0 0 2 2 2 0 Chromatin assembly factor complex 1 subunit p60, C-terminal DUF4200 PF13863.6 PFH35448.1 - 1.4e-19 70.6 10.2 1.4e-19 70.6 10.2 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF4200) Endotoxin_N PF03945.14 PFH35448.1 - 0.26 11.0 1.3 0.64 9.7 0.3 2.2 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain DUF948 PF06103.11 PFH35448.1 - 5.4 7.3 13.5 1.3 9.3 2.7 3.6 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) WXG100 PF06013.12 PFH35448.1 - 6.3 7.1 17.0 0.6 10.4 2.2 4.0 5 0 0 5 5 5 0 Proteins of 100 residues with WXG EF-hand_7 PF13499.6 PFH35450.1 - 3.3e-17 62.7 4.3 6.1e-11 42.6 0.2 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH35450.1 - 1.6e-14 52.5 7.2 7.1e-07 28.7 1.1 4.0 4 2 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 PFH35450.1 - 1.1e-13 49.7 9.7 1.2e-07 30.7 0.5 4.9 5 1 0 5 5 5 2 EF hand EF-hand_9 PF14658.6 PFH35450.1 - 9e-10 38.7 0.0 1.9e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PFH35450.1 - 1.3e-07 30.8 3.2 0.0002 20.7 1.7 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PFH35450.1 - 2.5e-07 30.4 4.6 0.0036 17.1 0.5 3.5 2 1 3 5 5 5 2 EF-hand domain pair tRNA-synt_1c_C PF03950.18 PFH35450.1 - 0.021 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Caleosin PF05042.13 PFH35450.1 - 0.028 14.4 0.3 0.81 9.6 0.0 2.3 2 0 0 2 2 2 0 Caleosin related protein EF-hand_14 PF17959.1 PFH35450.1 - 0.039 14.3 0.8 11 6.5 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain UPF0154 PF03672.13 PFH35450.1 - 0.092 12.8 0.0 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Glyco_transf_20 PF00982.21 PFH35453.1 - 1.2e-123 413.3 0.0 1.9e-123 412.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 PFH35453.1 - 1.2e-54 185.0 0.0 1.4e-52 178.2 0.0 2.3 2 0 0 2 2 2 2 Trehalose-phosphatase CBM_20 PF00686.19 PFH35453.1 - 1.9e-16 59.7 0.0 3.7e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain Hydrolase_3 PF08282.12 PFH35453.1 - 0.0012 18.7 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4854 PF16146.5 PFH35453.1 - 0.2 12.0 0.0 0.62 10.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) Elf1 PF05129.13 PFH35454.1 - 1.9e-27 95.1 0.5 2.9e-27 94.5 0.5 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 PFH35454.1 - 0.061 13.7 0.2 0.18 12.2 0.2 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 PFH35454.1 - 0.089 12.9 0.7 0.21 11.7 0.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain PAN_1 PF00024.26 PFH35455.1 - 9.8e-65 214.5 113.5 2.3e-05 24.3 5.6 12.4 6 6 6 12 12 12 12 PAN domain PAN_4 PF14295.6 PFH35455.1 - 1.5e-59 197.7 82.4 9e-05 22.3 1.0 12.6 12 0 0 12 12 12 12 PAN domain PAN_2 PF08276.11 PFH35455.1 - 9.6e-08 32.0 98.7 0.52 10.5 1.7 13.2 12 0 0 12 12 12 6 PAN-like domain zf-C4_Topoisom PF01396.19 PFH35455.1 - 1.6e-06 27.8 3.2 61 3.5 0.0 7.3 6 0 0 6 6 6 0 Topoisomerase DNA binding C4 zinc finger tRNA_int_endo_N PF02778.14 PFH35455.1 - 3.4e-06 26.6 5.6 22 4.8 0.0 5.5 5 0 0 5 5 5 0 tRNA intron endonuclease, N-terminal domain CHIPS PF11434.8 PFH35455.1 - 0.00023 20.9 0.0 1.2e+02 2.6 0.0 5.2 5 0 0 5 5 5 0 Chemotaxis-inhibiting protein CHIPS ETF PF01012.21 PFH35455.1 - 0.00036 20.5 5.6 1e+02 2.7 0.0 5.9 6 0 0 6 6 6 0 Electron transfer flavoprotein domain MANEC PF07502.14 PFH35455.1 - 0.00041 20.5 105.8 0.73 10.1 1.8 12.4 6 6 6 12 12 12 6 MANEC domain Mating_C PF12737.7 PFH35455.1 - 0.51 9.5 22.1 18 4.4 0.3 5.5 5 0 0 5 5 5 0 C-terminal domain of homeodomain 1 PAN_3 PF08277.12 PFH35455.1 - 1 9.2 83.9 4.5 7.2 0.7 12.3 12 0 0 12 12 12 0 PAN-like domain SLX9 PF15341.6 PFH35458.1 - 2e-11 44.4 0.0 2e-11 44.4 0.0 3.1 3 1 0 3 3 3 1 Ribosome biogenesis protein SLX9 DUF3669 PF12417.8 PFH35459.1 - 0.073 13.3 1.0 0.17 12.1 0.1 2.2 2 0 0 2 2 2 0 Zinc finger protein TarH PF02203.15 PFH35459.1 - 3.2 7.6 9.4 3.4 7.6 0.7 2.9 2 0 0 2 2 2 0 Tar ligand binding domain homologue DNA_gyraseB PF00204.25 PFH35460.1 - 1.3e-32 112.6 0.0 4.5e-21 75.1 0.7 3.1 3 0 0 3 3 3 2 DNA gyrase B DNA_gyraseB_C PF00986.21 PFH35460.1 - 6.8e-23 80.6 0.3 1.6e-22 79.4 0.3 1.6 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus Toprim PF01751.22 PFH35460.1 - 4.2e-17 62.2 0.0 1e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.26 PFH35460.1 - 4.3e-15 56.2 0.0 9.7e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SMC_N PF02463.19 PFH35462.1 - 6.6e-62 208.8 0.0 1.1e-61 208.1 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PFH35462.1 - 2.4e-16 60.1 0.1 7.3e-16 58.5 0.1 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 PFH35462.1 - 7.8e-10 39.0 1.1 0.00033 20.6 0.1 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 PFH35462.1 - 1.8e-09 38.4 8.7 1.8e-09 38.4 8.7 7.7 3 3 1 4 4 4 1 AAA domain ABC_tran PF00005.27 PFH35462.1 - 0.0019 18.8 0.3 0.0019 18.8 0.3 5.8 3 2 0 4 4 4 2 ABC transporter AAA_29 PF13555.6 PFH35462.1 - 0.0067 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Surfac_D-trimer PF09006.11 PFH35462.1 - 0.16 11.9 8.0 0.54 10.2 0.7 3.8 2 1 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF1515 PF07439.11 PFH35462.1 - 0.83 9.7 39.7 0.24 11.4 2.8 6.2 3 2 2 5 5 5 0 Protein of unknown function (DUF1515) Spc24 PF08286.11 PFH35463.1 - 0.011 15.9 0.3 0.037 14.3 0.3 1.9 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 YabA PF06156.13 PFH35463.1 - 0.012 16.2 0.3 0.034 14.8 0.3 1.8 1 0 0 1 1 1 0 Initiation control protein YabA DUF4254 PF14063.6 PFH35463.1 - 0.013 15.3 4.1 0.027 14.3 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) BST2 PF16716.5 PFH35463.1 - 0.042 14.4 1.4 0.042 14.4 1.4 2.9 3 1 1 4 4 3 0 Bone marrow stromal antigen 2 MbeD_MobD PF04899.12 PFH35463.1 - 0.067 13.3 7.1 0.19 11.8 6.9 1.8 1 1 0 1 1 1 0 MbeD/MobD like BBP1_C PF15272.6 PFH35463.1 - 0.099 12.5 1.9 0.24 11.2 1.9 1.7 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal ADIP PF11559.8 PFH35463.1 - 0.41 10.7 9.3 1.1 9.3 9.3 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 PFH35463.1 - 0.61 10.6 9.6 0.12 12.9 4.4 2.3 1 1 1 2 2 2 0 Cell division protein ZapB COMMD1_N PF17221.3 PFH35463.1 - 0.78 10.1 4.4 0.46 10.8 0.8 2.4 3 0 0 3 3 3 0 COMMD1 N-terminal domain FUSC PF04632.12 PFH35463.1 - 1 7.8 5.9 1.5 7.3 5.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4472 PF14739.6 PFH35463.1 - 1.1 10.0 8.3 0.14 12.9 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) JIP_LZII PF16471.5 PFH35463.1 - 1.2 9.4 4.6 0.26 11.5 0.8 1.9 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II GAS PF13851.6 PFH35463.1 - 1.5 8.2 14.1 2.1 7.6 0.2 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 PFH35463.1 - 1.9 8.3 5.8 3 7.7 4.3 2.2 1 1 1 2 2 2 0 Septum formation initiator MCU PF04678.13 PFH35463.1 - 2 8.5 5.9 4.5 7.3 5.9 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Endonuc_Holl PF10107.9 PFH35463.1 - 6.5 6.6 7.3 5.6 6.8 1.5 2.9 3 0 0 3 3 3 0 Endonuclease related to archaeal Holliday junction resolvase Erp_C PF06780.11 PFH35464.1 - 0.0076 16.3 0.4 0.019 14.9 0.4 1.6 1 1 0 1 1 1 1 Erp protein C-terminus DUF2175 PF09943.9 PFH35464.1 - 0.015 15.6 3.6 0.37 11.1 0.4 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF4407 PF14362.6 PFH35464.1 - 0.025 13.9 7.1 0.033 13.6 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAT PF03127.14 PFH35464.1 - 0.065 13.5 2.9 0.48 10.8 0.0 2.7 2 1 1 3 3 3 0 GAT domain YabA PF06156.13 PFH35464.1 - 0.076 13.7 3.2 1 10.0 2.5 2.4 2 1 0 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 PFH35464.1 - 0.084 13.4 11.3 0.44 11.1 11.2 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 PFH35464.1 - 0.084 12.4 6.0 0.063 12.9 3.6 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 PRKG1_interact PF15898.5 PFH35464.1 - 0.11 13.4 6.4 0.13 13.2 4.1 2.1 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain P_C10 PF14974.6 PFH35464.1 - 0.21 11.7 0.9 3.4 7.8 0.0 2.7 2 1 1 3 3 3 0 Protein C10 GIT_CC PF16559.5 PFH35464.1 - 0.38 10.7 7.0 3.6 7.5 0.2 3.4 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor MbeD_MobD PF04899.12 PFH35464.1 - 0.71 10.0 6.2 0.83 9.8 1.9 3.0 3 1 0 3 3 3 0 MbeD/MobD like CENP-H PF05837.12 PFH35464.1 - 0.88 10.0 11.4 1.5 9.3 3.0 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ABC_tran_CTD PF16326.5 PFH35464.1 - 0.93 9.8 11.3 0.21 11.9 4.3 2.4 3 0 0 3 3 2 0 ABC transporter C-terminal domain Seryl_tRNA_N PF02403.22 PFH35464.1 - 0.99 9.7 7.3 1.1 9.5 0.0 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RFamide_26RFa PF11109.8 PFH35464.1 - 1.4 9.4 5.2 9.4 6.8 0.2 2.4 1 1 2 3 3 3 0 Orexigenic neuropeptide Qrfp/P518 Lebercilin PF15619.6 PFH35464.1 - 2.4 7.8 16.2 7.9 6.1 0.4 2.8 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Plasmid_RAQPRD PF09686.10 PFH35464.1 - 2.5 8.4 8.8 15 5.9 0.4 3.5 3 1 2 5 5 5 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DivIC PF04977.15 PFH35464.1 - 3.1 7.7 13.0 3.3 7.6 0.5 3.2 2 1 1 3 3 3 0 Septum formation initiator Arm PF00514.23 PFH35466.1 - 1.4e-35 120.2 21.6 8.2e-08 32.0 0.0 9.7 11 0 0 11 11 10 7 Armadillo/beta-catenin-like repeat HEAT PF02985.22 PFH35466.1 - 1.6e-19 68.3 6.5 2.2e-05 24.3 0.0 7.6 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 PFH35466.1 - 2.6e-16 59.8 13.9 2.9e-05 24.4 0.1 5.1 2 2 1 4 4 4 4 HEAT repeats Cnd1 PF12717.7 PFH35466.1 - 5.5e-14 52.5 0.8 7.2e-05 22.9 0.2 4.0 2 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PFH35466.1 - 5.9e-12 45.8 16.1 0.011 16.2 0.4 6.0 4 1 3 7 7 6 5 HEAT-like repeat Adaptin_N PF01602.20 PFH35466.1 - 1.8e-09 36.7 3.2 0.00015 20.4 0.2 3.8 2 1 2 4 4 4 2 Adaptin N terminal region RICTOR_V PF14668.6 PFH35466.1 - 0.00014 22.1 0.2 2.8 8.3 0.0 4.1 4 0 0 4 4 3 1 Rapamycin-insensitive companion of mTOR, domain 5 Atx10homo_assoc PF09759.9 PFH35466.1 - 0.00022 21.2 0.9 0.093 12.8 0.1 3.8 3 1 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain Proteasom_PSMB PF10508.9 PFH35466.1 - 0.00027 19.6 3.9 0.002 16.7 0.6 3.1 1 1 2 3 3 3 1 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.8 PFH35466.1 - 0.0023 18.0 1.2 0.87 9.7 0.0 4.0 2 1 2 4 4 4 1 V-ATPase subunit H Mo25 PF08569.11 PFH35466.1 - 0.0064 15.9 0.4 0.2 11.0 0.1 2.8 2 1 0 2 2 2 1 Mo25-like DNA_alkylation PF08713.11 PFH35466.1 - 0.0079 15.9 0.6 35 4.0 0.1 3.6 3 1 0 3 3 3 0 DNA alkylation repair enzyme CLASP_N PF12348.8 PFH35466.1 - 0.008 15.8 5.0 0.55 9.8 0.1 2.7 3 0 0 3 3 3 2 CLASP N terminal Rcd1 PF04078.13 PFH35466.1 - 0.0086 15.4 0.1 1.1 8.5 0.0 2.8 3 0 0 3 3 3 1 Cell differentiation family, Rcd1-like Vac14_Fab1_bd PF12755.7 PFH35466.1 - 0.015 15.9 0.1 0.42 11.2 0.0 3.2 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 PFH35466.1 - 0.091 11.9 5.2 7.5 5.7 0.3 3.8 2 1 2 4 4 4 0 Nuclear condensing complex subunits, C-term domain DUF1018 PF06252.12 PFH35466.1 - 0.095 13.7 0.4 0.24 12.4 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) DUF3361 PF11841.8 PFH35466.1 - 0.12 12.4 0.9 16 5.4 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) HEAT_UF PF18817.1 PFH35466.1 - 0.18 12.1 1.8 4.7 7.6 0.1 4.1 6 0 0 6 6 4 0 Repeat of uncharacterized protein PH0542 HEAT_PBS PF03130.16 PFH35466.1 - 6.1 7.8 21.2 25 5.9 0.1 7.3 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat DNA_primase_lrg PF04104.14 PFH35469.1 - 4.2e-64 216.5 0.0 5.2e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Aminotran_4 PF01063.19 PFH35471.1 - 2e-19 70.4 0.0 2.6e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Tricorn_C1 PF14684.6 PFH35471.1 - 0.15 12.1 0.1 1.4 9.1 0.1 2.1 2 0 0 2 2 2 0 Tricorn protease C1 domain Nuc_rec_co-act PF08815.10 PFH35477.1 - 0.024 14.5 0.4 0.047 13.5 0.4 1.4 1 0 0 1 1 1 0 Nuclear receptor coactivator Fe-S_biosyn PF01521.20 PFH35478.1 - 2.5e-15 56.6 0.0 3.9e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SSB PF00436.25 PFH35479.1 - 3.5e-29 100.9 0.1 5.5e-29 100.3 0.1 1.3 1 0 0 1 1 1 1 Single-strand binding protein family Chorion_2 PF03964.15 PFH35479.1 - 0.28 12.0 4.8 1.2 10.1 0.2 2.8 2 0 0 2 2 2 0 Chorion family 2 Kinase-like PF14531.6 PFH35481.1 - 1e-19 70.9 0.0 1.6e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH35481.1 - 7.5e-13 48.4 0.0 1.2e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35481.1 - 5.9e-07 29.0 0.0 8.3e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF573 PF04504.14 PFH35481.1 - 0.12 13.0 2.2 2 9.1 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF573 Dynamitin PF04912.14 PFH35481.1 - 0.25 10.6 1.2 0.26 10.6 0.3 1.4 2 0 0 2 2 2 0 Dynamitin Peptidase_M18 PF02127.15 PFH35482.1 - 1.4e-144 482.2 0.0 1.6e-144 481.9 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 PFH35482.1 - 2.7e-06 26.6 0.0 0.00038 19.6 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Herpes_glycop PF01528.16 PFH35483.1 - 0.2 10.5 2.2 0.24 10.2 2.2 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M eIF3_p135 PF12807.7 PFH35484.1 - 7.3e-12 45.7 0.0 2.3e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 PFH35484.1 - 0.00049 20.3 7.3 0.0091 16.3 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DEAD PF00270.29 PFH35485.1 - 4.2e-48 163.4 0.0 2.3e-47 161.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH35485.1 - 3.8e-30 104.5 1.1 9.5e-30 103.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Hamartin PF04388.12 PFH35485.1 - 0.012 14.4 27.2 0.0036 16.0 24.6 1.4 1 1 0 1 1 1 0 Hamartin protein Ubiq_cyt_C_chap PF03981.12 PFH35486.1 - 4.7e-18 65.6 0.2 3.6e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone Host_attach PF10116.9 PFH35488.1 - 0.065 13.8 0.2 0.29 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein required for attachment to host cells Nse4_C PF08743.10 PFH35489.1 - 0.045 14.0 0.0 0.16 12.2 0.0 2.1 1 1 0 1 1 1 0 Nse4 C-terminal Thr_synth_N PF14821.6 PFH35490.1 - 2.9e-16 59.4 0.0 8.5e-16 57.9 0.0 1.8 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 PFH35490.1 - 3.6e-12 46.3 0.0 3.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Ion_trans PF00520.31 PFH35491.1 - 1e-29 103.5 29.9 5.4e-17 61.8 21.4 2.2 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 PFH35491.1 - 0.00014 20.7 11.9 0.00014 20.7 11.9 2.6 2 1 0 3 3 3 2 Polycystin cation channel OATP PF03137.20 PFH35491.1 - 0.057 11.7 3.4 0.11 10.8 3.4 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Kinase-like PF14531.6 PFH35492.1 - 2.8e-47 161.4 0.0 3.4e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH35492.1 - 4e-20 72.3 0.0 1.2e-14 54.3 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35492.1 - 0.0005 19.4 0.0 0.0066 15.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 PFH35492.1 - 0.0088 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Rv2175c_C PF18367.1 PFH35492.1 - 0.0098 16.0 0.1 0.033 14.3 0.1 1.9 1 0 0 1 1 1 1 Rv2175c C-terminal domain of unknown function Pox_ser-thr_kin PF05445.11 PFH35492.1 - 0.21 10.5 0.0 0.31 10.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CLPTM1 PF05602.12 PFH35493.1 - 1.7e-85 287.7 0.3 3e-83 280.2 0.1 2.5 3 0 0 3 3 3 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 PFH35493.1 - 5.1e-06 26.2 2.5 0.049 13.4 0.2 2.7 2 0 0 2 2 2 2 PQ loop repeat RTA1 PF04479.13 PFH35493.1 - 0.044 13.4 6.0 0.32 10.6 1.2 2.9 3 0 0 3 3 3 0 RTA1 like protein Transmemb_17 PF09799.9 PFH35493.1 - 5 7.8 8.3 2.8 8.6 0.8 2.4 1 1 1 2 2 2 0 Predicted membrane protein PRP1_N PF06424.12 PFH35494.1 - 3.5e-43 147.5 21.5 4.9e-43 147.1 1.0 4.1 4 0 0 4 4 3 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 PFH35494.1 - 6.8e-31 104.3 29.4 0.0026 18.4 0.6 15.0 6 3 10 16 16 15 10 Tetratricopeptide repeat TPR_19 PF14559.6 PFH35494.1 - 1.4e-22 80.0 9.9 0.012 16.1 0.0 9.7 8 2 2 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 PFH35494.1 - 3.2e-08 34.1 23.2 0.016 15.9 0.0 9.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 PFH35494.1 - 3.7e-08 32.9 15.6 1.6 9.0 0.2 9.5 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 PFH35494.1 - 2.8e-07 30.2 4.1 13 6.3 0.0 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 PFH35494.1 - 7.3e-05 22.4 0.0 1.9 8.3 0.0 5.6 5 1 1 6 6 6 1 TPR repeat ANAPC3 PF12895.7 PFH35494.1 - 0.00058 20.0 6.6 10 6.4 0.1 6.4 5 1 2 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PFH35494.1 - 0.00066 19.9 3.5 5.2 7.7 0.0 6.9 8 1 0 8 8 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 PFH35494.1 - 0.015 15.3 0.2 2.5 8.3 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 PFH35494.1 - 0.019 14.8 3.5 0.39 10.6 0.2 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 PFH35494.1 - 0.036 14.2 9.9 0.62 10.3 0.2 5.8 5 1 2 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH35494.1 - 0.043 14.5 9.7 56 4.7 0.0 8.0 9 0 0 9 9 8 0 Tetratricopeptide repeat ChAPs PF09295.10 PFH35494.1 - 0.048 12.7 4.8 12 4.8 0.1 4.0 2 1 2 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Suf PF05843.14 PFH35494.1 - 0.35 10.8 1.9 40 4.0 0.0 3.7 3 1 1 4 4 4 0 Suppressor of forked protein (Suf) TPR_12 PF13424.6 PFH35494.1 - 0.44 10.9 13.9 18 5.7 0.0 6.4 6 1 1 7 7 7 0 Tetratricopeptide repeat Tho2 PF11262.8 PFH35494.1 - 0.47 9.6 2.2 0.93 8.6 0.9 2.0 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TPR_21 PF09976.9 PFH35494.1 - 2.6 7.7 16.4 0.21 11.2 0.4 4.5 4 1 0 5 5 5 0 Tetratricopeptide repeat-like domain RESP18 PF14948.6 PFH35495.1 - 0.006 16.9 0.4 0.014 15.7 0.4 1.6 1 0 0 1 1 1 1 RESP18 domain RGS12_usC PF16612.5 PFH35495.1 - 0.018 15.5 0.1 0.029 14.8 0.1 1.3 1 0 0 1 1 1 0 C-terminal unstructured region of RGS12 GST_C_4 PF14834.6 PFH35495.1 - 0.031 14.7 0.3 0.063 13.7 0.1 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF676 PF05057.14 PFH35496.1 - 0.021 14.3 0.0 6.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Putative serine esterase (DUF676) RRM_1 PF00076.22 PFH35498.1 - 5.6e-22 77.4 0.1 9e-22 76.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 PFH35498.1 - 9.5e-16 58.2 1.3 9.5e-16 58.2 1.3 2.7 3 0 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_7 PF16367.5 PFH35498.1 - 0.00051 20.1 0.0 0.0016 18.5 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 PFH35498.1 - 0.016 15.5 0.1 0.031 14.5 0.1 1.5 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter MetallophosC PF16370.5 PFH35498.1 - 0.077 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase DUF155 PF02582.14 PFH35500.1 - 3.4e-41 141.2 0.1 5.8e-41 140.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 PPV_E1_C PF00519.17 PFH35500.1 - 0.22 10.3 0.3 0.31 9.8 0.3 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Sec7_N PF12783.7 PFH35502.1 - 2.8e-18 66.3 4.4 2.8e-18 66.3 4.4 2.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 PFH35502.1 - 5.9e-10 39.1 2.4 3.5e-06 26.8 0.6 2.8 2 0 0 2 2 2 2 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 PFH35502.1 - 4.1e-08 31.9 0.0 5.4e-05 21.6 0.0 2.3 2 0 0 2 2 2 2 C-terminal region of Mon2 protein Glyoxalase PF00903.25 PFH35503.1 - 8.8e-09 35.6 0.0 3.4e-07 30.5 0.0 2.5 3 0 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RANK_CRD_2 PF18278.1 PFH35503.1 - 0.12 12.6 0.1 0.35 11.1 0.1 1.7 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Glyoxalase_2 PF12681.7 PFH35503.1 - 0.19 11.7 0.1 0.42 10.5 0.0 1.5 2 0 0 2 2 2 0 Glyoxalase-like domain Bromodomain PF00439.25 PFH35506.1 - 0.038 14.1 0.3 0.1 12.7 0.3 1.8 1 0 0 1 1 1 0 Bromodomain DUF719 PF05334.13 PFH35506.1 - 0.29 11.3 2.5 7.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF719) PGAP1 PF07819.13 PFH35509.1 - 1.3e-09 38.1 0.0 2.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 PFH35509.1 - 0.072 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MFS_2 PF13347.6 PFH35509.1 - 0.24 9.9 2.2 4 5.9 0.0 3.0 2 1 1 3 3 3 0 MFS/sugar transport protein SF3b1 PF08920.10 PFH35511.1 - 2.1e-23 83.1 30.5 1.5e-21 77.1 12.5 4.8 2 2 1 3 3 3 2 Splicing factor 3B subunit 1 HEAT PF02985.22 PFH35511.1 - 5.9e-10 38.5 6.3 2.4 8.7 0.1 8.8 9 0 0 9 9 7 2 HEAT repeat HEAT_EZ PF13513.6 PFH35511.1 - 3e-08 34.0 6.1 0.1 13.1 0.0 7.2 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 PFH35511.1 - 7e-08 32.7 9.6 0.36 11.3 0.1 7.9 4 2 4 8 8 8 3 HEAT repeats Adaptin_N PF01602.20 PFH35511.1 - 5.4e-06 25.3 1.2 0.29 9.6 0.0 3.5 2 2 2 4 4 4 2 Adaptin N terminal region UME PF08064.13 PFH35511.1 - 0.00013 21.9 10.1 3.5 7.6 0.0 6.0 6 1 1 7 7 7 3 UME (NUC010) domain NUC173 PF08161.12 PFH35511.1 - 0.0014 18.3 0.0 2.4 7.8 0.0 3.6 3 0 0 3 3 3 2 NUC173 domain ParcG PF10274.9 PFH35511.1 - 0.0018 18.5 2.0 6.6 6.8 0.0 4.4 2 1 2 4 4 4 2 Parkin co-regulated protein Cnd1 PF12717.7 PFH35511.1 - 0.0042 17.1 5.7 39 4.2 0.0 6.4 6 1 2 8 8 8 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 PFH35511.1 - 0.013 15.7 7.7 9.6 6.4 0.1 5.0 5 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 PFH35511.1 - 0.015 14.9 0.1 2.7 7.5 0.0 2.9 3 0 0 3 3 3 0 CLASP N terminal IFRD PF05004.13 PFH35511.1 - 0.017 14.3 0.1 2.7 7.0 0.0 3.4 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 PFH35511.1 - 0.021 15.4 0.4 71 4.1 0.0 5.4 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region Arm PF00514.23 PFH35511.1 - 0.12 12.5 0.8 1.2e+02 2.9 0.0 5.0 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat His_Phos_1 PF00300.22 PFH35513.1 - 1.2e-07 31.7 0.0 0.00013 21.7 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) zf-RING_6 PF14835.6 PFH35513.1 - 1.3 9.0 4.9 3.8 7.4 2.7 2.4 1 1 1 2 2 2 0 zf-RING of BARD1-type protein DUF3510 PF12022.8 PFH35514.1 - 0.44 10.9 2.1 1.1 9.6 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) ketoacyl-synt PF00109.26 PFH35516.1 - 0 1145.2 4.8 1.1e-73 247.9 0.0 6.0 6 0 0 6 6 6 5 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PFH35516.1 - 1.8e-175 573.1 12.7 9.6e-36 122.4 0.0 5.7 5 0 0 5 5 5 5 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 PFH35516.1 - 3.1e-130 434.3 18.4 3.8e-44 151.5 0.5 3.3 3 0 0 3 3 3 3 Acyl transferase domain KR PF08659.10 PFH35516.1 - 3.6e-104 346.3 0.2 1.1e-51 175.3 0.0 3.7 3 0 0 3 3 3 2 KR domain PP-binding PF00550.25 PFH35516.1 - 3.9e-50 168.1 6.6 5.8e-12 45.8 0.0 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site PS-DH PF14765.6 PFH35516.1 - 1.6e-48 165.5 4.4 3.4e-40 138.1 0.8 2.9 2 1 0 2 2 2 2 Polyketide synthase dehydratase NAD_binding_4 PF07993.12 PFH35516.1 - 1.8e-33 115.8 0.0 2.6e-32 112.0 0.0 3.0 3 1 0 3 3 3 1 Male sterility protein KAsynt_C_assoc PF16197.5 PFH35516.1 - 8.2e-25 87.4 0.1 2.4e-05 24.8 0.0 5.1 5 0 0 5 5 4 4 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 PFH35516.1 - 8.5e-20 71.0 0.1 1.4e-08 34.4 0.0 2.9 2 0 0 2 2 2 2 short chain dehydrogenase Thiolase_N PF00108.23 PFH35516.1 - 4.1e-12 46.0 12.6 0.0085 15.5 0.1 5.6 5 0 0 5 5 5 4 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 PFH35516.1 - 3.5e-06 26.4 0.0 0.12 11.5 0.0 3.4 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein Epimerase PF01370.21 PFH35516.1 - 1.9e-05 24.3 1.5 1.7 8.1 0.1 3.5 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PFH35516.1 - 8.2e-05 22.2 0.2 0.15 11.4 0.0 3.1 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase Secretin_N PF03958.17 PFH35516.1 - 0.01 16.2 2.8 58 4.2 0.1 4.4 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain YjeF_N PF03853.15 PFH35516.1 - 0.016 15.1 0.5 0.92 9.4 0.1 2.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus DprA_WH PF17782.1 PFH35516.1 - 0.058 13.5 6.8 28 4.9 0.2 3.9 3 0 0 3 3 3 0 DprA winged helix domain DUF4070 PF13282.6 PFH35516.1 - 0.17 12.0 0.0 1.6e+02 2.4 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4070) ApbA PF02558.16 PFH35516.1 - 0.18 11.5 1.4 12 5.5 0.1 2.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3Beta_HSD PF01073.19 PFH35516.1 - 0.84 8.6 3.6 18 4.2 0.1 3.1 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding PF00501.28 PFH35518.1 - 0.00087 18.0 1.8 0.14 10.7 0.0 3.5 4 0 0 4 4 4 3 AMP-binding enzyme AAA_lid_6 PF17866.1 PFH35518.1 - 0.084 13.1 0.2 0.084 13.1 0.2 3.2 3 0 0 3 3 3 0 AAA lid domain Ribo_biogen_C PF04034.13 PFH35519.1 - 1.1e-39 135.1 0.0 1.6e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 PFH35519.1 - 9.5e-09 34.9 0.2 1.9e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI RelB_transactiv PF16181.5 PFH35521.1 - 0.032 14.5 0.1 9.8 6.4 0.0 2.4 2 0 0 2 2 2 0 RelB transactivation domain PhoD PF09423.10 PFH35522.1 - 1.9e-07 30.5 2.3 1.4e-06 27.6 2.3 2.3 1 1 0 1 1 1 1 PhoD-like phosphatase Nop14 PF04147.12 PFH35523.1 - 1.2 7.3 12.5 1.5 6.9 12.5 1.2 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.32 PFH35524.1 - 0.0056 17.5 1.8 1 10.3 0.1 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat SEEEED PF14797.6 PFH35525.1 - 0.00033 20.8 16.5 0.00033 20.8 16.5 3.7 2 1 1 3 3 3 1 Serine-rich region of AP3B1, clathrin-adaptor complex DnaJ PF00226.31 PFH35526.1 - 1e-21 76.8 1.1 2e-21 75.9 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 PFH35526.1 - 9.1e-10 38.5 0.0 2.9e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 PFH35526.1 - 5.3e-05 23.2 0.0 0.0022 18.0 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like domain DUF2201 PF09967.9 PFH35526.1 - 0.16 12.1 0.1 0.72 10.0 0.0 2.1 2 0 0 2 2 2 0 VWA-like domain (DUF2201) cNMP_binding PF00027.29 PFH35527.1 - 1.1e-18 67.0 0.1 6.5e-12 45.4 0.0 2.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain HMGL-like PF00682.19 PFH35528.1 - 1.1e-43 149.8 0.3 6.5e-43 147.2 0.3 1.9 1 1 0 1 1 1 1 HMGL-like PsbX PF06596.11 PFH35528.1 - 0.055 13.5 1.0 0.12 12.4 1.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) cNMP_binding PF00027.29 PFH35529.1 - 1.5e-19 69.8 0.0 1.6e-05 24.9 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain EB PF01683.18 PFH35530.1 - 0.0037 17.5 31.0 0.53 10.6 0.1 9.6 7 7 1 8 8 8 2 EB module Antistasin PF02822.14 PFH35530.1 - 0.057 14.1 39.9 0.32 11.7 0.1 11.1 7 2 4 11 11 11 0 Antistasin family FOG_N PF15888.5 PFH35530.1 - 0.078 13.4 46.3 0.21 12.0 0.8 10.4 5 2 7 12 12 12 0 Folded gastrulation N-terminus cEGF PF12662.7 PFH35530.1 - 0.097 12.6 61.5 3.7 7.5 0.2 12.2 14 1 0 14 14 14 0 Complement Clr-like EGF-like Secapin PF17521.2 PFH35530.1 - 0.11 12.3 0.0 0.11 12.3 0.0 10.6 10 3 2 12 12 12 0 Honey bee peptides TIL PF01826.17 PFH35530.1 - 0.18 12.1 50.4 2.8 8.2 1.4 11.5 4 2 4 8 8 8 0 Trypsin Inhibitor like cysteine rich domain Sushi PF00084.20 PFH35530.1 - 5 7.8 23.2 19 5.9 0.3 8.3 7 2 2 9 9 9 0 Sushi repeat (SCR repeat) Prok-E2_C PF14459.6 PFH35530.1 - 6.3 7.0 10.9 40 4.4 0.1 4.8 3 2 2 6 6 6 0 Prokaryotic E2 family C Calcyon PF06387.11 PFH35530.1 - 7 6.6 28.0 2.5 8.1 0.3 8.1 7 3 3 10 10 10 0 D1 dopamine receptor-interacting protein (calcyon) Exo_endo_phos PF03372.23 PFH35531.1 - 4.3e-13 49.3 0.0 4.5e-12 46.0 0.0 2.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ATP-synt_ab PF00006.25 PFH35532.1 - 5e-72 242.0 0.0 7.3e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 PFH35532.1 - 6.6e-48 162.2 1.4 1.1e-47 161.4 1.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 PFH35532.1 - 1.2e-16 61.0 4.6 3.6e-16 59.4 4.6 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 PFH35532.1 - 0.00016 21.8 1.5 0.00042 20.4 1.5 1.8 1 0 0 1 1 1 1 HAS barrel domain 2OG-FeII_Oxy_2 PF13532.6 PFH35533.1 - 4.3e-07 30.3 0.0 7.5e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IQCJ-SCHIP1 PF15157.6 PFH35533.1 - 5.9 6.7 7.7 10 5.9 7.7 1.3 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif EFF-AFF PF14884.6 PFH35534.1 - 0.11 10.7 0.0 0.16 10.0 0.0 1.1 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen MPC PF03650.13 PFH35535.1 - 3e-33 114.3 0.2 3.6e-33 114.0 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 PFH35535.1 - 0.066 13.3 0.1 0.089 12.8 0.1 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange SAG PF04092.13 PFH35536.1 - 6.7e-30 104.6 0.3 7.2e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 SRS domain HIGH_NTase1 PF05636.11 PFH35537.1 - 0.076 12.2 1.4 0.092 11.9 0.3 1.6 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase PKcGMP_CC PF16808.5 PFH35537.1 - 7.5 6.5 10.0 0.5 10.2 0.8 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF155 PF02582.14 PFH35538.1 - 2.6e-50 170.9 0.0 4.9e-50 170.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 BING4CT PF08149.11 PFH35539.1 - 1.2e-32 111.6 0.0 5.7e-31 106.2 0.0 2.8 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 PFH35539.1 - 0.0015 19.3 3.5 0.055 14.4 0.2 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat WD40_like PF17005.5 PFH35539.1 - 0.12 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain AAA_2 PF07724.14 PFH35540.1 - 4.1e-51 173.5 1.0 3.1e-47 160.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 PFH35540.1 - 1.5e-33 114.9 1.9 1.5e-33 114.9 1.9 3.0 1 1 2 3 3 3 1 AAA lid domain AAA PF00004.29 PFH35540.1 - 9.2e-23 81.1 1.3 6.8e-13 49.2 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 PFH35540.1 - 2.3e-22 78.8 0.1 1.3e-21 76.5 0.1 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 PFH35540.1 - 5.9e-16 58.3 0.4 4.5e-10 39.5 0.0 3.1 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 PFH35540.1 - 2.4e-14 53.5 0.1 7.4e-09 35.7 0.0 3.7 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PFH35540.1 - 4.8e-11 43.3 7.5 2.4e-05 24.8 0.1 4.3 3 2 1 5 5 5 2 AAA ATPase domain IstB_IS21 PF01695.17 PFH35540.1 - 1.5e-08 34.6 0.1 0.007 16.1 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 PFH35540.1 - 2.5e-08 34.3 2.6 0.0046 17.2 0.1 5.1 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 PFH35540.1 - 1.3e-07 31.5 0.0 0.00042 20.1 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.6 PFH35540.1 - 1.7e-07 31.9 0.0 0.023 15.3 0.0 3.2 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 PFH35540.1 - 9.3e-07 29.0 5.4 0.051 13.5 0.0 4.1 4 1 0 4 4 3 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 PFH35540.1 - 1.7e-06 28.1 0.0 0.044 13.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 PFH35540.1 - 3.4e-05 23.4 0.0 0.052 13.0 0.0 2.5 2 1 0 2 2 2 2 P-loop containing dynein motor region Roc PF08477.13 PFH35540.1 - 4.8e-05 23.5 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 PFH35540.1 - 6.9e-05 23.2 0.0 0.12 12.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 PFH35540.1 - 0.00029 20.8 0.4 0.91 9.4 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase RuvB_N PF05496.12 PFH35540.1 - 0.00036 20.3 1.2 3.9 7.2 0.0 4.2 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 PFH35540.1 - 0.0004 19.8 0.1 3.2 7.1 0.0 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 PFH35540.1 - 0.00041 20.3 0.0 0.23 11.3 0.0 2.9 3 0 0 3 3 2 1 NACHT domain ABC_tran PF00005.27 PFH35540.1 - 0.00067 20.2 2.0 0.083 13.4 0.0 3.6 3 1 0 3 3 3 1 ABC transporter AAA_28 PF13521.6 PFH35540.1 - 0.00073 19.8 0.0 0.86 9.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 PFH35540.1 - 0.00092 19.2 0.0 0.41 10.7 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 PFH35540.1 - 0.0033 17.2 0.8 4.1 7.1 0.0 3.3 3 1 0 3 3 2 1 AAA domain ResIII PF04851.15 PFH35540.1 - 0.0088 16.1 0.0 0.92 9.5 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit TIP49 PF06068.13 PFH35540.1 - 0.013 14.7 0.6 1.2 8.3 0.0 3.0 2 1 1 3 3 3 0 TIP49 P-loop domain DNA_pol3_delta2 PF13177.6 PFH35540.1 - 0.014 15.1 0.0 1.4 8.7 0.0 3.2 2 1 0 2 2 2 0 DNA polymerase III, delta subunit Zeta_toxin PF06414.12 PFH35540.1 - 0.018 14.3 0.0 2 7.7 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 PFH35540.1 - 0.023 14.8 0.0 5.4 7.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 PFH35540.1 - 0.087 12.7 0.0 17 5.3 0.0 2.8 2 0 0 2 2 2 0 NTPase Ras PF00071.22 PFH35540.1 - 0.11 12.1 0.0 15 5.2 0.0 2.8 2 0 0 2 2 2 0 Ras family AAA_3 PF07726.11 PFH35540.1 - 0.11 12.3 0.0 27 4.6 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 PFH35540.1 - 0.15 11.8 0.0 0.68 9.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation V_ATPase_I PF01496.19 PFH35540.1 - 0.15 9.9 1.8 0.22 9.4 1.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Troponin PF00992.20 PFH35540.1 - 0.23 11.7 13.7 0.76 10.1 13.7 2.0 1 0 0 1 1 1 0 Troponin AAA_19 PF13245.6 PFH35540.1 - 0.24 11.7 4.2 2.3 8.5 0.4 3.9 4 1 0 4 4 2 0 AAA domain ATP_bind_1 PF03029.17 PFH35540.1 - 0.34 10.6 1.0 13 5.5 0.0 3.3 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 PFH35540.1 - 0.51 10.4 4.2 13 5.8 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain PolyA_pol PF01743.20 PFH35540.1 - 0.67 10.4 3.2 26 5.3 0.0 2.7 2 0 0 2 2 2 0 Poly A polymerase head domain AAA_17 PF13207.6 PFH35540.1 - 0.83 10.1 5.9 5.7 7.4 0.1 3.5 3 1 0 3 3 2 0 AAA domain ABC_tran_CTD PF16326.5 PFH35540.1 - 1.2 9.5 26.4 0.42 10.9 7.5 3.7 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF4407 PF14362.6 PFH35540.1 - 1.6 8.0 11.3 3.9 6.7 11.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_23 PF13476.6 PFH35540.1 - 2.9 8.3 20.0 54 4.2 0.0 3.7 2 1 0 2 2 1 0 AAA domain Peptidase_S46 PF10459.9 PFH35540.1 - 3.9 6.0 8.5 6.7 5.2 8.5 1.4 1 0 0 1 1 1 0 Peptidase S46 Img2 PF05046.14 PFH35543.1 - 2.5e-14 53.3 0.0 3.9e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) MRI PF15325.6 PFH35543.1 - 0.24 12.5 1.7 0.53 11.4 1.7 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection FBP_C PF16571.5 PFH35544.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger OTU PF02338.19 PFH35544.1 - 0.054 14.0 0.0 0.15 12.6 0.0 1.8 1 1 0 1 1 1 0 OTU-like cysteine protease DEC-1_N PF04625.13 PFH35545.1 - 0.019 14.0 2.3 0.02 13.9 2.3 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region GTP_EFTU PF00009.27 PFH35546.1 - 8.1e-46 156.0 0.0 3.5e-45 153.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 PFH35546.1 - 6e-14 51.8 0.0 1.2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 PFH35546.1 - 8.2e-07 29.0 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 PFH35546.1 - 0.00034 20.4 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV YIF1 PF03878.15 PFH35547.1 - 1.3e-33 116.5 0.8 2.8e-32 112.1 0.1 2.1 2 0 0 2 2 2 2 YIF1 Glutaredoxin PF00462.24 PFH35548.1 - 4.9e-13 49.1 0.0 8.9e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Cmc1 PF08583.10 PFH35549.1 - 2.6e-07 30.5 5.1 2.6e-07 30.5 5.1 1.6 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 PFH35549.1 - 0.0051 16.5 3.1 0.0089 15.7 3.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 PFH35549.1 - 0.13 12.4 4.5 0.32 11.2 4.3 1.7 1 1 0 1 1 1 0 CHCH domain COX17 PF05051.13 PFH35549.1 - 0.39 11.1 7.9 0.11 12.8 3.1 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) RRM_1 PF00076.22 PFH35550.1 - 8.8e-22 76.7 0.0 1.2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PFH35550.1 - 0.0044 16.6 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PFH35550.1 - 0.008 16.2 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif RRM_7 PF16367.5 PFH35550.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 PFH35550.1 - 0.042 13.7 0.0 0.087 12.7 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 PFH35550.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Sigma70_ner PF04546.13 PFH35551.1 - 0.4 10.5 3.2 0.82 9.5 3.3 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.14 PFH35551.1 - 5.6 5.1 7.8 7.1 4.8 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 PFH35551.1 - 10 5.4 10.3 14 4.9 10.3 1.1 1 0 0 1 1 1 0 NOA36 protein DSPc PF00782.20 PFH35552.1 - 2e-18 66.5 3.8 1.1e-17 64.1 0.1 3.3 4 0 0 4 4 4 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PFH35552.1 - 0.0052 16.4 0.5 0.01 15.4 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase RUN PF02759.19 PFH35552.1 - 0.039 13.9 0.1 0.088 12.8 0.1 1.5 1 0 0 1 1 1 0 RUN domain Apt1 PF10351.9 PFH35553.1 - 0.73 8.6 0.0 0.73 8.6 0.0 3.7 5 0 0 5 5 5 0 Golgi-body localisation protein domain CK_II_beta PF01214.18 PFH35555.1 - 3.4e-62 209.5 0.0 4.3e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit P22_Cro PF14549.6 PFH35555.1 - 0.18 11.7 0.3 0.36 10.7 0.3 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro Sof1 PF04158.14 PFH35555.1 - 0.28 11.5 0.1 0.28 11.5 0.1 1.9 2 0 0 2 2 2 0 Sof1-like domain Solute_trans_a PF03619.16 PFH35556.1 - 6.6e-12 45.5 3.3 2.7e-05 23.8 0.2 2.2 2 0 0 2 2 2 2 Organic solute transporter Ostalpha TMEM132D_C PF15706.5 PFH35556.1 - 0.035 13.9 0.0 0.32 10.8 0.0 2.4 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term MT-A70 PF05063.14 PFH35558.1 - 1.1e-45 155.7 0.2 9.7e-44 149.3 0.2 2.2 1 1 0 1 1 1 1 MT-A70 Enolase_C PF00113.22 PFH35559.1 - 5.3e-148 492.0 0.1 6.5e-148 491.8 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 PFH35559.1 - 3.8e-57 192.1 0.0 8.1e-57 191.0 0.0 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 PFH35559.1 - 2.8e-10 40.2 0.0 4.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 PFH35559.1 - 3.9e-05 22.9 0.0 6.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DUF4848 PF16140.5 PFH35559.1 - 0.092 12.3 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4848) Enolase_C PF00113.22 PFH35560.1 - 2e-139 463.9 0.0 2.4e-139 463.6 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 PFH35560.1 - 4.1e-48 162.9 0.0 7.1e-48 162.1 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 PFH35560.1 - 6.7e-07 29.1 0.0 1.4e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 PFH35560.1 - 0.00015 21.0 0.1 0.00025 20.3 0.1 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus GFO_IDH_MocA PF01408.22 PFH35561.1 - 1.6e-05 25.7 0.0 3.9e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TPR_14 PF13428.6 PFH35561.1 - 2.8e-05 24.6 0.0 0.85 10.6 0.0 3.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 PFH35561.1 - 3.5e-05 23.4 0.0 0.00015 21.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 PFH35561.1 - 6.5e-05 22.8 0.0 0.03 14.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 PFH35561.1 - 0.00024 21.3 0.0 0.47 10.8 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 PFH35561.1 - 0.00033 20.5 0.0 0.01 15.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 PFH35561.1 - 0.0068 16.9 0.0 0.022 15.3 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 PFH35561.1 - 0.059 13.4 0.1 1.6 9.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Citrate_synt PF00285.21 PFH35563.1 - 1.8e-97 326.6 0.0 5.6e-97 325.0 0.0 1.6 2 0 0 2 2 2 1 Citrate synthase, C-terminal domain Tex_N PF09371.10 PFH35563.1 - 0.12 12.0 0.3 0.36 10.5 0.1 1.7 2 0 0 2 2 2 0 Tex-like protein N-terminal domain DWNN PF08783.11 PFH35564.1 - 7e-05 23.0 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-C3HC4_3 PF13920.6 PFH35564.1 - 0.018 14.9 9.0 0.038 13.9 9.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 PFH35564.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-RING_2 PF13639.6 PFH35564.1 - 0.16 12.3 10.5 0.42 11.0 10.5 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 PFH35564.1 - 0.48 10.3 11.8 0.95 9.4 11.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH35564.1 - 1.3 9.1 6.3 1.4 9.0 4.7 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 PFH35564.1 - 9.5 6.3 14.1 2.8 8.0 10.5 2.0 2 0 0 2 2 2 0 zinc-RING finger domain Peptidase_S24 PF00717.23 PFH35565.1 - 1.5e-09 37.7 0.0 2.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 PFH35565.1 - 0.0001 22.1 0.0 0.0016 18.2 0.0 2.2 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 IPK PF03770.16 PFH35566.1 - 6.3e-25 88.2 0.0 9.4e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase EH_Signature PF15611.6 PFH35567.1 - 0.079 12.4 1.5 0.11 11.9 1.5 1.1 1 0 0 1 1 1 0 EH_Signature domain BTB PF00651.31 PFH35568.1 - 9.4e-05 22.6 0.5 0.00018 21.7 0.2 1.6 2 0 0 2 2 2 1 BTB/POZ domain E2 PF08199.11 PFH35568.1 - 0.013 15.4 0.3 0.041 13.8 0.2 1.9 2 0 0 2 2 2 0 Bacteriophage E2-like protein DUF3223 PF11523.8 PFH35569.1 - 2.6e-17 63.4 0.2 6e-17 62.3 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3223) La PF05383.17 PFH35569.1 - 3.7e-11 42.9 0.0 7.3e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 La domain DUF2691 PF10903.8 PFH35569.1 - 0.091 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2691) AMPK1_CBM PF16561.5 PFH35570.1 - 1.5e-30 105.2 0.2 2.4e-30 104.6 0.2 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase SPOR PF05036.13 PFH35572.1 - 0.13 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Sporulation related domain ABC_tran PF00005.27 PFH35574.1 - 2.1e-38 131.9 0.0 4.2e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 PFH35574.1 - 3.2e-23 82.7 2.2 4.4e-23 82.3 2.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 PFH35574.1 - 6.1e-07 29.1 0.0 2.3e-05 23.9 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain DUF815 PF05673.13 PFH35574.1 - 0.00039 19.7 0.0 0.00071 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 PFH35574.1 - 0.00045 19.5 0.0 0.00097 18.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 PFH35574.1 - 0.0036 17.2 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 PFH35574.1 - 0.0043 16.8 0.0 0.0099 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 PFH35574.1 - 0.0046 17.4 0.5 0.023 15.1 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 PFH35574.1 - 0.01 15.9 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 PFH35574.1 - 0.017 15.4 0.0 0.08 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 PFH35574.1 - 0.018 14.9 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PFH35574.1 - 0.021 14.5 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 PFH35574.1 - 0.035 14.2 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_membrane_2 PF06472.15 PFH35574.1 - 0.043 13.2 0.9 0.072 12.5 0.9 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 AAA_24 PF13479.6 PFH35574.1 - 0.045 13.5 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 PFH35574.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_33 PF13671.6 PFH35574.1 - 0.11 12.7 0.1 0.27 11.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PFH35574.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ACDC PF14733.6 PFH35575.1 - 2.9e-18 66.0 0.0 4.7e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 PFH35575.1 - 2.3e-06 27.7 0.4 5.8e-06 26.4 0.4 1.7 1 0 0 1 1 1 1 AP2 domain MSC PF09402.10 PFH35576.1 - 4.8e-14 52.6 0.3 9.7e-13 48.3 0.0 2.1 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain Glyco_trans_2_3 PF13632.6 PFH35576.1 - 0.17 11.8 2.7 1.3 8.9 0.4 2.3 2 0 0 2 2 2 0 Glycosyl transferase family group 2 NDK PF00334.19 PFH35577.1 - 1.5e-67 225.8 0.0 2.8e-29 101.8 0.0 5.4 4 1 1 5 5 5 4 Nucleoside diphosphate kinase ADK PF00406.22 PFH35577.1 - 1.8e-18 67.1 0.0 6.6e-07 29.5 0.0 3.7 4 0 0 4 4 4 3 Adenylate kinase AAA_17 PF13207.6 PFH35577.1 - 1.1e-08 35.5 0.0 0.0007 20.0 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 PFH35577.1 - 0.002 18.7 0.0 1.6 9.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain Dpy-30 PF05186.13 PFH35577.1 - 0.0088 15.7 0.1 0.065 12.9 0.0 2.3 2 0 0 2 2 2 1 Dpy-30 motif SKI PF01202.22 PFH35577.1 - 0.077 13.1 0.2 2.2 8.4 0.1 3.2 2 1 0 2 2 2 0 Shikimate kinase IPK PF03770.16 PFH35578.1 - 0.00023 21.1 0.0 0.00045 20.1 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase Aminotran_3 PF00202.21 PFH35581.1 - 8.2e-113 377.1 0.0 1e-112 376.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III adh_short PF00106.25 PFH35582.1 - 1.2e-36 126.0 0.0 1.8e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PFH35582.1 - 4.5e-27 95.1 0.0 6.2e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PFH35582.1 - 4.2e-09 36.6 0.0 7.1e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 PFH35582.1 - 0.056 12.8 0.0 0.15 11.4 0.0 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TRAPP PF04051.16 PFH35584.1 - 5e-36 123.6 0.0 6e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF3793 PF12672.7 PFH35584.1 - 0.019 15.0 0.1 0.033 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) DHHC PF01529.20 PFH35585.1 - 2.2e-31 108.7 7.9 2.2e-31 108.7 7.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase SNARE PF05739.19 PFH35585.1 - 2.7 8.1 7.1 0.33 11.0 0.2 2.5 2 0 0 2 2 2 0 SNARE domain Baculo_11_kDa PF06143.11 PFH35585.1 - 3.1 7.4 10.4 0.41 10.3 0.2 2.9 3 0 0 3 3 3 0 Baculovirus 11 kDa family Wzy_C PF04932.15 PFH35585.1 - 7.5 6.2 7.7 0.12 12.0 0.2 1.8 2 1 0 2 2 2 0 O-Antigen ligase Med9 PF07544.13 PFH35586.1 - 0.0087 16.1 0.4 0.0087 16.1 0.4 5.0 3 2 1 5 5 5 1 RNA polymerase II transcription mediator complex subunit 9 RBD-FIP PF09457.10 PFH35586.1 - 0.078 12.9 1.3 1.1 9.2 0.0 3.3 3 0 0 3 3 3 0 FIP domain PI_PP_I PF18363.1 PFH35586.1 - 0.21 11.8 5.2 7.7 6.8 0.0 3.4 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain EzrA PF06160.12 PFH35586.1 - 0.21 9.7 33.6 1.2 7.3 6.9 3.3 2 2 0 2 2 2 0 Septation ring formation regulator, EzrA PRANC PF09372.10 PFH35586.1 - 0.46 10.8 4.4 2.7 8.4 1.3 2.9 3 0 0 3 3 3 0 PRANC domain DUF1664 PF07889.12 PFH35586.1 - 2.6 8.1 27.1 1.6 8.8 0.2 4.8 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 PFH35586.1 - 7 6.4 18.5 4.7 7.0 0.3 3.8 2 1 2 4 4 4 0 Hepatic lectin, N-terminal domain DUF4746 PF15928.5 PFH35587.1 - 2.2 7.6 7.4 2.7 7.3 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1682 PF07946.14 PFH35587.1 - 3.2 6.9 6.2 4.8 6.3 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) HVSL PF09749.9 PFH35588.1 - 2e-28 99.5 0.4 2.2e-19 69.9 1.2 2.2 2 0 0 2 2 2 2 Uncharacterised conserved protein MIF4G PF02854.19 PFH35589.1 - 9.1e-32 110.4 2.8 1.6e-31 109.6 2.8 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 PFH35589.1 - 0.094 12.7 5.0 0.25 11.3 0.4 2.4 2 0 0 2 2 2 0 MA3 domain Gp_dh_C PF02800.20 PFH35590.1 - 1.3e-64 216.6 0.8 3.3e-64 215.2 0.0 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 PFH35590.1 - 1.1e-36 125.2 0.0 2.7e-36 124.0 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TPR_14 PF13428.6 PFH35591.1 - 1.2e-29 100.4 24.8 0.00018 22.1 0.0 12.2 7 4 5 12 12 12 7 Tetratricopeptide repeat HAT PF02184.16 PFH35591.1 - 5.5e-21 74.2 58.0 2.7e-05 24.0 0.1 14.3 13 1 0 13 13 13 6 HAT (Half-A-TPR) repeat Suf PF05843.14 PFH35591.1 - 2.1e-14 54.2 20.9 0.0061 16.6 1.4 6.7 1 1 6 7 7 7 7 Suppressor of forked protein (Suf) TPR_19 PF14559.6 PFH35591.1 - 1.1e-11 45.1 0.3 0.58 10.7 0.0 7.5 5 1 4 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 PFH35591.1 - 1.9e-10 40.0 24.0 2.1 8.7 0.1 10.5 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 PFH35591.1 - 8.7e-08 32.0 1.2 8 7.1 0.0 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 PFH35591.1 - 3.7e-07 29.8 9.9 6.5 7.2 0.1 8.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 PFH35591.1 - 7.5e-07 29.4 21.0 1.4 9.7 0.0 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 PFH35591.1 - 6.9e-06 26.6 14.1 2.1 9.1 0.1 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 PFH35591.1 - 5.8e-05 22.4 12.8 0.08 12.1 1.2 5.0 2 2 2 4 4 4 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PFH35591.1 - 0.00067 19.6 18.5 0.54 10.2 1.0 6.3 7 0 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 PFH35591.1 - 0.0065 16.7 14.9 17 5.8 0.0 7.7 9 1 0 9 9 7 0 Tetratricopeptide repeat Glyco_transf_88 PF16849.5 PFH35591.1 - 0.17 10.8 0.3 0.27 10.1 0.3 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 88 U3_assoc_6 PF08640.11 PFH35591.1 - 0.22 11.6 18.0 0.048 13.7 2.0 6.0 5 2 1 6 6 6 0 U3 small nucleolar RNA-associated protein 6 TPR_9 PF13371.6 PFH35591.1 - 0.35 11.1 0.0 0.35 11.1 0.0 5.9 9 0 0 9 9 8 0 Tetratricopeptide repeat Actin PF00022.19 PFH35593.1 - 1.3e-27 96.5 0.0 4.2e-19 68.4 0.0 2.9 3 0 0 3 3 3 2 Actin Lipase_GDSL_2 PF13472.6 PFH35593.1 - 0.0055 17.1 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family eIF-5a PF01287.20 PFH35593.1 - 0.2 11.8 0.1 0.44 10.7 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold JAB PF01398.21 PFH35594.1 - 1.9e-29 102.0 0.2 8.2e-29 100.0 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 PFH35594.1 - 7.4e-28 97.2 0.4 1.2e-27 96.6 0.4 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Cation_ATPase_C PF00689.21 PFH35595.1 - 4.5 6.9 10.5 35 4.0 10.0 2.4 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus LRR_4 PF12799.7 PFH35596.1 - 5e-09 36.3 0.4 4.3e-06 27.0 0.2 2.9 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH35596.1 - 2e-05 24.2 0.0 0.0058 16.4 0.0 3.1 2 1 1 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 PFH35596.1 - 0.0003 20.6 0.1 0.027 14.5 0.0 3.5 4 0 0 4 4 4 1 Leucine Rich repeat LRR_9 PF14580.6 PFH35596.1 - 0.15 11.5 0.0 0.41 10.1 0.0 1.7 2 0 0 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 PFH35596.1 - 1.1 10.0 2.9 6.8 7.7 0.0 3.6 5 0 0 5 5 5 0 Leucine Rich Repeat Lipase_3 PF01764.25 PFH35598.1 - 3e-17 62.8 0.0 5.3e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) zf-CCCH PF00642.24 PFH35599.1 - 0.0027 17.6 0.0 0.0027 17.6 0.0 4.3 3 2 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PFH35599.1 - 0.011 15.6 3.5 0.11 12.3 1.5 3.3 3 1 0 3 3 3 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PFH35599.1 - 0.22 11.6 0.1 0.22 11.6 0.1 3.7 4 0 0 4 4 4 0 Zinc finger domain FUSC_2 PF13515.6 PFH35600.1 - 3.8e-06 27.0 9.2 3.8e-06 27.0 9.2 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 PFH35600.1 - 0.57 8.9 8.9 1.2 7.9 8.9 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter CENP-H PF05837.12 PFH35601.1 - 0.1 13.0 0.8 0.18 12.2 0.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) AbrB PF05145.12 PFH35601.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Transition state regulatory protein AbrB Dmrt1 PF12374.8 PFH35602.1 - 0.59 10.6 3.7 0.98 9.9 0.4 2.6 2 1 0 2 2 2 0 Double-sex mab3 related transcription factor 1 RE_XamI PF09572.10 PFH35603.1 - 0.54 9.9 2.8 1.1 8.9 2.8 1.4 1 0 0 1 1 1 0 XamI restriction endonuclease THEG4 PF15834.5 PFH35603.1 - 0.97 9.4 5.2 2 8.4 1.1 2.9 2 0 0 2 2 2 0 Testis highly expressed protein 4 SSI PF00720.17 PFH35605.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Subtilisin inhibitor-like CRAL_TRIO PF00650.20 PFH35608.1 - 2.7e-24 85.7 0.0 4.3e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 PFH35608.1 - 0.0082 16.6 0.1 0.14 12.6 0.0 2.5 1 1 1 2 2 2 1 Golgi-dynamics membrane-trafficking adh_short PF00106.25 PFH35609.1 - 4.1e-35 121.0 0.0 7.2e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PFH35609.1 - 1.3e-19 70.7 0.0 2.4e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PFH35609.1 - 0.00021 21.2 0.0 0.00045 20.2 0.0 1.5 1 0 0 1 1 1 1 KR domain zf-ribbon_3 PF13248.6 PFH35610.1 - 0.054 12.9 0.3 4.2 6.9 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-dskA_traR PF01258.17 PFH35610.1 - 0.083 12.9 0.6 2.2 8.3 0.1 2.6 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Nudix_N_2 PF14803.6 PFH35610.1 - 0.11 12.4 3.5 4.7 7.2 0.1 3.1 3 0 0 3 3 3 0 Nudix N-terminal zf_C2H2_13 PF18508.1 PFH35610.1 - 0.12 12.0 0.1 0.3 10.7 0.1 1.6 1 0 0 1 1 1 0 Zinc finger domain RIG-I_C-RD PF11648.8 PFH35610.1 - 0.17 12.2 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I polyprenyl_synt PF00348.17 PFH35613.1 - 1.4e-58 197.9 0.0 3.1e-58 196.9 0.0 1.5 2 0 0 2 2 2 1 Polyprenyl synthetase PIF1 PF05970.14 PFH35613.1 - 0.26 10.4 0.0 0.39 9.8 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase EF-hand_1 PF00036.32 PFH35614.1 - 1.2e-21 74.6 0.4 7.4e-07 28.3 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PFH35614.1 - 7.3e-20 69.2 0.2 2e-07 30.4 0.1 3.5 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 PFH35614.1 - 6.6e-19 68.1 0.0 8.4e-12 45.4 0.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PFH35614.1 - 1.7e-11 43.7 0.2 2.4e-06 27.3 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PFH35614.1 - 2.7e-11 42.4 1.5 0.00014 21.2 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 PFH35614.1 - 2.5e-07 30.9 0.0 0.0023 18.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 PFH35614.1 - 0.00013 22.8 0.0 0.00017 22.4 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain Dockerin_1 PF00404.18 PFH35614.1 - 0.002 18.3 0.0 1.1 9.5 0.0 2.8 2 1 1 3 3 3 1 Dockerin type I domain MHCassoc_trimer PF08831.10 PFH35614.1 - 0.0047 16.9 0.2 0.49 10.4 0.1 2.2 2 0 0 2 2 2 1 Class II MHC-associated invariant chain trimerisation domain SPARC_Ca_bdg PF10591.9 PFH35614.1 - 0.013 15.8 0.0 0.15 12.4 0.0 2.1 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 PFH35614.1 - 0.024 15.0 0.0 5 7.5 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Caleosin PF05042.13 PFH35614.1 - 0.064 13.2 0.1 16 5.4 0.0 2.7 2 2 1 3 3 3 0 Caleosin related protein CBS PF00571.28 PFH35614.1 - 0.087 13.3 0.0 0.2 12.1 0.0 1.7 1 1 0 1 1 1 0 CBS domain YfiO PF13525.6 PFH35615.1 - 0.034 13.9 0.6 0.053 13.2 0.6 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein PhoR PF11808.8 PFH35615.1 - 0.18 12.2 2.0 0.33 11.4 2.0 1.4 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR PPP4R2 PF09184.11 PFH35615.1 - 3.8 7.0 7.7 5.8 6.4 7.7 1.3 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 PFH35615.1 - 5.4 6.2 9.4 9.2 5.5 9.4 1.3 1 0 0 1 1 1 0 NOA36 protein Metallophos PF00149.28 PFH35616.1 - 2.8e-22 80.2 0.0 4.5e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_6 PF13405.6 PFH35616.1 - 0.00016 21.3 0.0 0.00043 20.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 PFH35616.1 - 0.0024 18.3 1.5 0.0036 17.7 0.3 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PFH35616.1 - 0.032 13.7 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 PFH35616.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 EF hand Adap_comp_sub PF00928.21 PFH35617.1 - 1.1e-47 162.6 0.0 1.7e-47 162.0 0.0 1.3 1 1 0 1 1 1 1 Adaptor complexes medium subunit family 14-3-3 PF00244.20 PFH35618.1 - 1.3e-78 263.5 1.8 1.5e-78 263.4 1.8 1.0 1 0 0 1 1 1 1 14-3-3 protein Biotin_lipoyl PF00364.22 PFH35619.1 - 7.3e-15 54.6 0.1 1.4e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_D23 PF16576.5 PFH35619.1 - 3.2e-07 29.8 0.1 0.0053 16.0 0.0 2.6 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 PFH35619.1 - 4e-07 29.8 0.0 0.014 15.2 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 PFH35619.1 - 5e-06 27.2 0.1 0.11 13.2 0.0 3.1 3 0 0 3 3 3 2 HlyD family secretion protein DUF2118 PF09891.9 PFH35619.1 - 0.0024 17.9 0.1 0.0044 17.0 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 PFH35619.1 - 0.0057 16.5 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 PFH35619.1 - 0.015 15.3 0.2 0.44 10.5 0.1 2.7 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Kelch_4 PF13418.6 PFH35620.1 - 0.15 12.1 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Galactose oxidase, central domain SUZ PF12752.7 PFH35621.1 - 3.8e-09 37.2 0.5 3.8e-09 37.2 0.5 4.3 3 2 0 3 3 3 1 SUZ domain FAM183 PF14886.6 PFH35622.1 - 2.1e-20 73.5 0.5 2.1e-20 73.5 0.5 1.6 2 0 0 2 2 2 1 FAM183A and FAM183B related EF-hand_7 PF13499.6 PFH35623.1 - 0.0038 17.6 0.3 0.041 14.3 0.1 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PFH35623.1 - 0.0092 15.8 0.2 0.21 11.6 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain SAG PF04092.13 PFH35624.1 - 5.1e-50 169.7 14.1 1.5e-25 90.5 5.4 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH35625.1 - 3.6e-48 163.7 13.3 1.7e-24 87.0 4.7 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH35626.1 - 3.9e-13 50.3 0.0 1.7e-12 48.3 0.0 1.8 1 1 0 1 1 1 1 SRS domain SAG PF04092.13 PFH35627.1 - 8.7e-48 162.4 19.8 1.2e-24 87.5 6.9 2.1 2 0 0 2 2 2 2 SRS domain Ig_5 PF16681.5 PFH35627.1 - 0.27 11.6 2.3 28 5.2 0.3 2.8 2 1 1 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain PS_Dcarbxylase PF02666.15 PFH35629.1 - 3.5e-25 88.7 0.0 4.4e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase WD40 PF00400.32 PFH35630.1 - 1e-17 64.2 23.6 0.00042 21.1 0.3 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH35630.1 - 1.4e-08 34.9 1.2 6.4e-05 23.2 0.1 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 PFH35630.1 - 0.001 18.7 0.1 0.0022 17.6 0.1 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain Peptidase_M16_M PF16187.5 PFH35633.1 - 3.5e-36 124.9 0.0 2.4e-34 118.9 0.0 2.3 2 0 0 2 2 2 2 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 PFH35633.1 - 3e-32 111.7 0.1 1.4e-31 109.5 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PFH35633.1 - 1.8e-27 96.5 0.0 5.1e-17 62.5 0.0 3.5 3 0 0 3 3 3 3 Peptidase M16 inactive domain DUF2870 PF11069.8 PFH35635.1 - 9.6e-38 128.5 0.1 1.7e-37 127.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) ubiquitin PF00240.23 PFH35635.1 - 0.063 13.0 1.2 0.54 10.0 0.0 2.6 3 0 0 3 3 3 0 Ubiquitin family JAB PF01398.21 PFH35636.1 - 4.2e-32 110.6 1.1 5.5e-32 110.2 0.1 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 PFH35636.1 - 2.5e-09 36.9 0.0 3.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.6 PFH35636.1 - 2.9e-09 37.3 0.4 5.6e-09 36.4 0.4 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function GLTSCR1 PF15249.6 PFH35636.1 - 0.094 13.2 0.8 0.18 12.3 0.8 1.6 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein RAP PF08373.10 PFH35637.1 - 8e-09 35.5 0.0 1.2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 RAP domain DUF559 PF04480.12 PFH35637.1 - 5.6e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF559) MTES_1575 PF18741.1 PFH35637.1 - 6.4e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 REase_MTES_1575 He_PIG PF05345.12 PFH35637.1 - 0.12 12.6 0.9 0.26 11.5 0.9 1.5 1 0 0 1 1 1 0 Putative Ig domain DUF2931 PF11153.8 PFH35637.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) NAD_synthase PF02540.17 PFH35638.1 - 3.9e-27 94.9 0.1 5.7e-14 51.8 0.0 2.6 2 1 0 2 2 2 2 NAD synthase CN_hydrolase PF00795.22 PFH35638.1 - 1.3e-24 86.9 0.0 1.8e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Arf PF00025.21 PFH35639.1 - 1.5e-13 50.5 0.0 1.9e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PFH35639.1 - 0.00011 22.2 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 PFH35639.1 - 0.00016 21.8 0.0 0.00031 21.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 PFH35639.1 - 0.078 13.4 0.1 0.3 11.4 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain RuvB_N PF05496.12 PFH35639.1 - 0.099 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Ras PF00071.22 PFH35639.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Ras family AAA_18 PF13238.6 PFH35639.1 - 0.12 12.9 0.1 0.49 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PFH35639.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 PFH35639.1 - 0.19 11.1 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PFH35639.1 - 0.2 11.6 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Utp21 PF04192.12 PFH35640.1 - 7.4e-36 123.8 0.0 1.4e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 PFH35640.1 - 4.1e-12 46.4 6.3 0.027 15.4 0.0 8.0 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH35640.1 - 5.7e-09 36.1 0.0 0.14 12.4 0.0 6.1 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PFH35640.1 - 3.4e-08 33.4 0.5 0.21 11.1 0.0 3.8 2 2 1 3 3 3 3 PQQ-like domain PD40 PF07676.12 PFH35640.1 - 0.00057 19.8 0.6 0.0027 17.6 0.1 2.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Lgl_C PF08596.10 PFH35640.1 - 0.07 11.8 0.0 14 4.3 0.0 3.1 3 0 0 3 3 3 0 Lethal giant larvae(Lgl) like, C-terminal HCMV_UL124 PF17609.2 PFH35640.1 - 1.2 9.3 4.6 0.92 9.7 0.7 2.5 2 0 0 2 2 2 0 Family of unknown function Chromo PF00385.24 PFH35641.1 - 3.5e-14 52.5 0.6 4e-10 39.4 0.5 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF1388 PF07142.12 PFH35641.1 - 0.17 11.8 20.4 1.1 9.3 7.9 3.2 1 1 1 2 2 2 0 Repeat of unknown function (DUF1388) CRCB PF02537.15 PFH35642.1 - 6.1e-21 74.5 5.3 2.4e-12 47.0 0.5 3.2 3 1 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) AAA_11 PF13086.6 PFH35643.1 - 1.7e-59 201.7 0.0 1.7e-59 201.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 PFH35643.1 - 1.5e-56 191.2 0.0 2.4e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PFH35643.1 - 2.9e-11 43.5 2.6 8.6e-09 35.4 0.1 2.9 3 0 0 3 3 3 2 AAA domain R3H PF01424.22 PFH35643.1 - 7.4e-11 41.9 0.0 3.7e-10 39.6 0.0 2.3 1 0 0 1 1 1 1 R3H domain AAA_19 PF13245.6 PFH35643.1 - 4.3e-08 33.6 0.0 5.9e-05 23.4 0.0 3.4 2 2 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 PFH35643.1 - 1.3e-07 31.6 0.1 0.068 12.9 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 PFH35643.1 - 0.0001 21.9 0.1 0.00029 20.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 PFH35643.1 - 0.00024 21.0 0.3 0.038 13.9 0.0 3.3 3 0 0 3 3 3 1 Helicase AAA_22 PF13401.6 PFH35643.1 - 0.0003 21.1 0.1 0.002 18.4 0.0 2.5 2 0 0 2 2 1 1 AAA domain DUF2075 PF09848.9 PFH35643.1 - 0.0014 18.0 0.6 0.2 10.9 0.0 3.3 3 1 1 4 4 4 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 PFH35643.1 - 0.0066 16.3 0.0 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 PFH35643.1 - 0.011 16.2 5.0 0.06 13.7 2.9 3.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 PFH35643.1 - 0.011 15.9 0.0 0.045 13.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 PFH35643.1 - 0.055 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 PFH35643.1 - 0.2 11.0 0.0 0.62 9.4 0.0 1.8 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 PFH35643.1 - 0.22 11.4 0.0 0.48 10.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSF PF00482.23 PFH35643.1 - 2.9 7.8 8.3 2.4 8.2 0.5 3.5 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F CBM_4_9 PF02018.17 PFH35644.1 - 0.02 15.1 0.2 0.022 15.0 0.2 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain Pkinase PF00069.25 PFH35645.1 - 1.9e-29 102.8 0.0 1.6e-28 99.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35645.1 - 9.4e-11 41.5 0.0 2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3437 PF11919.8 PFH35646.1 - 0.16 11.9 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Med26 PF08711.11 PFH35647.1 - 6e-05 23.0 0.1 0.00011 22.1 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SR-25 PF10500.9 PFH35647.1 - 0.004 16.8 14.2 0.004 16.8 14.2 2.8 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein NIF PF03031.18 PFH35648.1 - 3e-22 79.0 0.0 4.9e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LIG3_BRCT PF16759.5 PFH35648.1 - 0.018 15.3 0.0 0.59 10.5 0.0 2.8 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain Goodbye PF17109.5 PFH35649.1 - 0.076 13.5 16.0 1.6 9.2 0.2 5.0 4 1 0 4 4 4 0 fungal STAND N-terminal Goodbye domain Med10 PF09748.9 PFH35649.1 - 0.34 10.9 0.0 0.34 10.9 0.0 4.2 3 1 1 4 4 4 0 Transcription factor subunit Med10 of Mediator complex NPV_P10 PF05531.12 PFH35649.1 - 4.6 7.8 22.0 12 6.5 0.1 7.6 5 3 2 7 7 7 0 Nucleopolyhedrovirus P10 protein Carboxyl_trans PF01039.22 PFH35650.1 - 1.3e-134 449.6 0.0 1.7e-134 449.2 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 PFH35650.1 - 0.00013 21.6 0.7 0.035 13.6 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) ERCC3_RAD25_C PF16203.5 PFH35652.1 - 1.7e-107 358.3 0.1 2.5e-107 357.7 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 PFH35652.1 - 1.1e-29 103.2 0.0 2.2e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH35652.1 - 2.5e-15 56.9 0.0 4.5e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PFH35652.1 - 1.3e-12 48.1 0.1 7.7e-12 45.5 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 PFH35652.1 - 5.2e-05 22.1 0.0 8.4e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain LSM14 PF12701.7 PFH35653.1 - 8.8e-31 105.8 0.0 1.3e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 PFH35653.1 - 6.1e-08 32.7 0.0 9.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 PFH35653.1 - 2.8e-07 31.3 9.9 6.8e-07 30.1 9.9 1.6 1 1 0 1 1 1 1 FDF domain SAG PF04092.13 PFH35654.1 - 1.5e-47 161.7 21.8 1.5e-25 90.5 7.2 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH35655.1 - 2.2e-46 157.9 12.5 3.8e-24 85.9 1.2 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH35656.1 - 6.9e-48 162.8 19.8 1.3e-24 87.4 4.8 2.1 2 0 0 2 2 2 2 SRS domain Ig_5 PF16681.5 PFH35656.1 - 0.017 15.5 1.9 0.43 11.0 0.0 3.0 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain SAG PF04092.13 PFH35657.1 - 4.7e-29 101.8 10.7 5.7e-23 82.1 0.8 2.3 2 0 0 2 2 2 2 SRS domain Pilus_CpaD PF09476.10 PFH35658.1 - 0.087 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Peptidase_C11 PF03415.14 PFH35659.1 - 9e-23 81.2 0.0 2.2e-22 80.0 0.0 1.5 1 1 0 1 1 1 1 Clostripain family EGF_CA PF07645.15 PFH35659.1 - 3.6e-16 59.1 42.0 6.1e-09 35.9 6.2 4.8 4 0 0 4 4 4 3 Calcium-binding EGF domain cEGF PF12662.7 PFH35659.1 - 1.6e-11 43.9 35.1 1.8e-06 27.8 4.3 4.3 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.7 PFH35659.1 - 2.9e-11 43.4 39.8 1.2e-05 25.3 5.9 4.2 4 0 0 4 4 4 3 EGF domain FXa_inhibition PF14670.6 PFH35659.1 - 0.0031 17.7 6.1 0.0031 17.7 6.1 5.4 5 0 0 5 5 5 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 PFH35659.1 - 0.0054 17.0 31.6 0.0072 16.6 2.3 4.6 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 PFH35659.1 - 0.77 10.5 26.7 0.097 13.3 2.3 4.4 4 0 0 4 4 4 0 Human growth factor-like EGF ASCH PF04266.14 PFH35661.1 - 9e-10 39.1 0.0 2.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.13 PFH35661.1 - 4.1e-06 26.7 9.3 9.3e-06 25.5 9.3 1.6 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Evr1_Alr PF04777.13 PFH35662.1 - 6.3e-08 33.0 2.0 0.021 15.3 0.1 3.6 3 0 0 3 3 3 3 Erv1 / Alr family OST3_OST6 PF04756.13 PFH35662.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 PFH35662.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 PFH35662.1 - 0.12 12.6 0.0 0.12 12.6 0.0 2.1 3 0 0 3 3 3 0 Thioredoxin 14-3-3 PF00244.20 PFH35663.1 - 2e-31 109.2 0.2 2e-24 86.3 0.0 2.1 2 0 0 2 2 2 2 14-3-3 protein SARAF PF06682.12 PFH35664.1 - 0.71 9.5 8.6 0.92 9.1 8.6 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SpoIIIAH PF12685.7 PFH35664.1 - 1.4 8.7 7.9 0.096 12.5 0.9 1.9 1 1 1 2 2 2 0 SpoIIIAH-like protein SecY PF00344.20 PFH35665.1 - 1.3e-71 241.4 14.8 1.6e-71 241.1 14.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 PFH35665.1 - 1.2e-17 63.5 0.6 3.3e-17 62.0 0.0 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p DUF1765 PF08578.10 PFH35666.1 - 1.1e-14 54.9 6.7 6.4e-14 52.5 6.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) C2 PF00168.30 PFH35666.1 - 0.0013 19.0 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Epimerase PF01370.21 PFH35667.1 - 2.4e-17 63.2 0.0 1.1e-16 61.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 PFH35667.1 - 0.0032 17.0 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 PFH35667.1 - 0.0077 15.4 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 PFH35667.1 - 0.012 15.0 0.0 0.39 10.1 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 PFH35667.1 - 0.019 14.5 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase AAA_28 PF13521.6 PFH35667.1 - 0.022 15.0 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rrn6 PF10214.9 PFH35668.1 - 2.6 6.4 12.3 0.0073 14.9 2.6 1.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor PS_Dcarbxylase PF02666.15 PFH35669.1 - 8.2e-29 100.6 0.0 1.6e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Longin PF13774.6 PFH35672.1 - 1.4e-20 73.1 0.0 2.2e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 PFH35672.1 - 2.6e-16 59.2 0.0 4.5e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin KinB_sensor PF16767.5 PFH35672.1 - 0.14 12.7 3.1 0.34 11.4 0.3 2.5 2 1 1 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB AAA_12 PF13087.6 PFH35673.1 - 6.2e-41 140.2 0.0 2.3e-40 138.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PFH35673.1 - 1.4e-13 51.2 1.7 8.6e-07 29.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 PFH35673.1 - 6.5e-10 39.0 0.0 2.4e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PFH35673.1 - 3.1e-08 34.1 0.0 4.5e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PFH35673.1 - 0.0033 17.7 0.0 0.016 15.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 PFH35673.1 - 0.0057 16.4 0.0 0.053 13.3 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 PFH35673.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Aldo_ket_red PF00248.21 PFH35674.1 - 2.7e-52 177.8 0.0 9e-52 176.1 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Thioredoxin PF00085.20 PFH35675.1 - 2.5e-23 82.0 0.1 3.2e-23 81.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 PFH35675.1 - 2e-06 27.6 0.0 2.7e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 PFH35675.1 - 5.3e-06 26.7 0.0 0.0037 17.5 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 PFH35675.1 - 2.3e-05 24.8 0.1 8.7e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 PFH35675.1 - 0.00011 21.6 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 PFH35675.1 - 0.00045 20.0 0.1 0.00087 19.0 0.1 1.3 1 1 0 1 1 1 1 Redoxin DIM1 PF02966.16 PFH35675.1 - 0.0057 16.4 0.0 0.007 16.2 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_4 PF13462.6 PFH35675.1 - 0.02 15.0 0.1 1.2 9.2 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 PFH35675.1 - 0.053 13.8 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin DUF953 PF06110.11 PFH35675.1 - 0.057 13.0 0.3 0.25 10.9 0.3 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) AhpC-TSA PF00578.21 PFH35675.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family KaiB PF07689.12 PFH35675.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 KaiB domain DIM1 PF02966.16 PFH35676.1 - 6.9e-66 220.0 0.3 7.8e-66 219.9 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 PFH35676.1 - 0.0013 18.7 0.1 0.0016 18.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin RAP PF08373.10 PFH35677.1 - 0.098 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 RAP domain LRR_2 PF07723.13 PFH35678.1 - 0.1 13.3 0.1 0.22 12.2 0.1 1.6 1 0 0 1 1 1 0 Leucine Rich Repeat PP2C PF00481.21 PFH35680.1 - 3.2e-09 36.8 0.9 0.00011 21.9 0.1 3.0 2 1 0 2 2 2 2 Protein phosphatase 2C MFS_1 PF07690.16 PFH35681.1 - 0.00088 18.3 8.8 0.00088 18.3 8.8 3.0 2 2 0 2 2 2 1 Major Facilitator Superfamily Kinesin PF00225.23 PFH35682.1 - 1.8e-47 161.9 0.0 2.7e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PFH35682.1 - 1.2e-12 48.0 0.0 2.1e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding FlxA PF14282.6 PFH35682.1 - 0.88 9.6 5.2 3.3 7.8 4.8 2.2 2 0 0 2 2 2 0 FlxA-like protein Mannosyl_trans2 PF04188.13 PFH35683.1 - 5.4e-24 85.3 3.5 1e-10 41.6 0.0 5.4 6 0 0 6 6 6 5 Mannosyltransferase (PIG-V) DUF1178 PF06676.11 PFH35685.1 - 0.77 10.1 3.6 1.2 9.5 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1178) DUF3535 PF12054.8 PFH35686.1 - 0.038 13.3 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) Adeno_E4_34 PF04528.13 PFH35687.1 - 0.14 12.0 0.2 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region UPF0121 PF03661.13 PFH35688.1 - 3.8e-13 49.4 4.6 5.6e-13 48.8 4.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) IQ PF00612.27 PFH35689.1 - 0.00074 19.1 0.2 0.002 17.8 0.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif EMP24_GP25L PF01105.24 PFH35689.1 - 0.68 9.8 14.6 1.9 8.4 14.0 2.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ZZ PF00569.17 PFH35693.1 - 9.8e-06 25.3 4.8 2.3e-05 24.1 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type FYVE PF01363.21 PFH35693.1 - 0.094 12.9 3.6 0.22 11.7 3.6 1.6 1 0 0 1 1 1 0 FYVE zinc finger C1_2 PF03107.16 PFH35693.1 - 0.93 9.9 5.7 2.5 8.5 5.7 1.8 1 0 0 1 1 1 0 C1 domain PP-binding_2 PF14573.6 PFH35694.1 - 1e-47 160.3 3.1 1.4e-47 159.8 3.1 1.2 1 0 0 1 1 1 1 Acyl-carrier PP-binding PF00550.25 PFH35694.1 - 0.0023 18.3 0.1 0.0046 17.3 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site GRASP55_65 PF04495.14 PFH35694.1 - 0.16 12.3 0.1 2.7 8.3 0.0 2.1 1 1 1 2 2 2 0 GRASP55/65 PDZ-like domain PP2C PF00481.21 PFH35695.1 - 3.8e-39 134.9 0.0 5.1e-35 121.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 PFH35695.1 - 0.0051 16.8 0.2 0.15 12.0 0.0 2.6 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) Pkinase PF00069.25 PFH35696.1 - 1.3e-57 195.2 0.4 1.4e-26 93.4 0.3 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35696.1 - 5e-26 91.5 3.5 7.4e-21 74.6 1.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 PFH35696.1 - 0.013 15.5 0.1 0.047 13.6 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 PFH35696.1 - 0.014 15.0 0.2 0.022 14.4 0.2 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 PFH35696.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 PFH35696.1 - 0.037 13.0 0.0 0.049 12.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 PFH35696.1 - 0.18 10.5 0.6 0.51 9.1 0.1 1.7 1 1 1 2 2 2 0 Fungal protein kinase Kdo PF06293.14 PFH35696.1 - 0.22 10.9 1.2 0.44 9.9 1.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BTB PF00651.31 PFH35697.1 - 1.6e-07 31.6 0.0 1.9e-06 28.1 0.0 2.5 1 1 0 1 1 1 1 BTB/POZ domain CD52 PF15116.6 PFH35698.1 - 0.12 12.4 0.1 0.12 12.4 0.1 3.2 2 1 0 2 2 2 0 CAMPATH-1 antigen Clat_adaptor_s PF01217.20 PFH35700.1 - 4.9e-47 159.4 0.1 1.7e-40 138.3 0.3 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Herpes_env PF01673.18 PFH35700.1 - 0.021 13.8 0.0 0.024 13.6 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Ribosomal_S13_N PF08069.12 PFH35701.1 - 5e-26 90.5 0.2 9.1e-26 89.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 PFH35701.1 - 2.3e-13 50.1 1.3 2.3e-13 50.1 1.3 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 MCM PF00493.23 PFH35702.1 - 2.3e-44 151.2 0.4 1.1e-39 135.9 0.6 3.2 3 0 0 3 3 3 3 MCM P-loop domain MCM_lid PF17855.1 PFH35702.1 - 1e-10 41.9 0.0 0.00057 20.3 0.0 2.6 2 0 0 2 2 2 2 MCM AAA-lid domain Mg_chelatase PF01078.21 PFH35702.1 - 1.3e-06 27.9 1.2 0.00021 20.7 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_OB PF17207.3 PFH35702.1 - 8.9e-05 22.3 0.0 0.00028 20.7 0.0 1.8 1 1 0 1 1 1 1 MCM OB domain Sigma54_activat PF00158.26 PFH35702.1 - 0.00031 20.5 0.2 0.00031 20.5 0.2 2.0 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 PFH35702.1 - 0.0081 16.2 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 PFH35702.1 - 0.15 11.5 0.1 0.26 10.8 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region tRNA-synt_2 PF00152.20 PFH35703.1 - 3.3e-79 266.2 0.0 7e-66 222.4 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PFH35703.1 - 6.9e-08 32.4 0.1 2.2e-07 30.8 0.1 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PFH35703.1 - 0.00098 18.7 0.1 0.0038 16.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) YhfZ_C PF14503.6 PFH35703.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 YhfZ C-terminal domain UFD1 PF03152.14 PFH35705.1 - 2e-69 232.5 0.0 2.4e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 PFH35705.1 - 0.00018 21.3 0.0 0.0007 19.3 0.0 1.9 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 Trm112p PF03966.16 PFH35706.1 - 1.3e-17 64.1 0.0 2.8e-17 63.0 0.0 1.5 1 1 0 1 1 1 1 Trm112p-like protein mRNA_decap_C PF16741.5 PFH35706.1 - 0.038 13.3 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus CENP-C_C PF11699.8 PFH35706.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like Aldedh PF00171.22 PFH35707.1 - 1e-19 70.4 0.1 2.1e-10 39.7 0.1 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family PrpR_N PF06506.11 PFH35707.1 - 0.054 13.1 0.0 2.5 7.6 0.0 2.6 2 0 0 2 2 2 0 Propionate catabolism activator E1_dh PF00676.20 PFH35707.1 - 0.07 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Pro_isomerase PF00160.21 PFH35708.1 - 1.8e-51 174.6 0.0 2.1e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LEA_1 PF03760.15 PFH35709.1 - 5.9 7.6 17.5 0.092 13.4 7.2 2.8 2 0 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 HECT PF00632.25 PFH35710.1 - 4.1e-54 184.2 0.0 6.6e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 PFH35710.1 - 2.5e-05 24.4 0.0 7.1e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 SPRY domain Laminin_G_3 PF13385.6 PFH35710.1 - 0.00036 20.7 0.0 0.0095 16.1 0.0 2.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily UBA PF00627.31 PFH35710.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain DUF1150 PF06620.11 PFH35710.1 - 0.61 10.2 2.5 7.8 6.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1150) p25-alpha PF05517.12 PFH35711.1 - 3.4e-36 124.7 3.3 4e-36 124.5 3.3 1.0 1 0 0 1 1 1 1 p25-alpha UvrA_DNA-bind PF17755.1 PFH35711.1 - 0.055 13.8 0.0 0.094 13.1 0.0 1.4 1 0 0 1 1 1 0 UvrA DNA-binding domain EF-hand_6 PF13405.6 PFH35711.1 - 0.082 12.9 0.1 1.8 8.7 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain DEAD PF00270.29 PFH35712.1 - 7.4e-32 110.5 0.0 2.9e-24 85.8 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH35712.1 - 5.4e-20 71.8 0.0 2.1e-19 69.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_1 PF00076.22 PFH35713.1 - 1.3e-17 63.3 0.0 2.2e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Coprogen_oxidas PF01218.18 PFH35713.1 - 0.079 11.7 0.3 0.11 11.2 0.3 1.1 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase DeoC PF01791.9 PFH35714.1 - 6.5e-21 75.0 0.1 7.6e-21 74.8 0.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase Dynamin_N PF00350.23 PFH35717.1 - 8.4e-14 52.0 0.0 2.4e-13 50.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 PFH35717.1 - 0.00021 21.3 0.0 0.00057 19.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Wbp11 PF09429.10 PFH35719.1 - 3.7e-16 59.3 12.9 3.7e-16 59.3 12.9 1.9 2 0 0 2 2 2 1 WW domain binding protein 11 Nipped-B_C PF12830.7 PFH35720.1 - 0.00071 19.6 0.1 0.002 18.1 0.1 1.7 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus PHD PF00628.29 PFH35720.1 - 0.079 12.9 0.2 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 PHD-finger Cwf_Cwc_15 PF04889.12 PFH35721.1 - 8.2e-53 179.7 23.0 4.8e-40 137.9 12.4 2.0 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 PFH35721.1 - 0.21 11.4 20.3 0.023 14.5 15.9 1.5 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing Asp-B-Hydro_N PF05279.11 PFH35721.1 - 0.59 10.2 11.9 0.71 9.9 11.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDC45 PF02724.14 PFH35721.1 - 1.9 6.6 10.0 1.9 6.7 10.0 1.2 1 0 0 1 1 1 0 CDC45-like protein APG6_N PF17675.1 PFH35721.1 - 8.2 7.0 19.7 3.3 8.2 11.9 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region HHH_5 PF14520.6 PFH35723.1 - 6.1e-05 23.5 0.0 0.001 19.7 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain Asn_synthase PF00733.21 PFH35724.1 - 1.4e-11 44.7 3.6 2.9e-05 23.9 1.9 3.3 2 1 0 2 2 2 2 Asparagine synthase PWI PF01480.17 PFH35725.1 - 1.2e-13 51.1 0.2 2.7e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 PFH35725.1 - 3.6e-08 33.1 0.0 7.6e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GREB1 PF15782.5 PFH35725.1 - 6.9 3.6 14.9 12 2.8 14.9 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RNA_pol_Rpb6 PF01192.22 PFH35726.1 - 1.7e-16 59.8 0.1 2.4e-16 59.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF1168 PF06658.12 PFH35727.1 - 1e-18 67.5 16.0 1e-18 67.5 16.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1168) DUF572 PF04502.13 PFH35727.1 - 7.6 6.1 22.3 10 5.6 22.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) PseudoU_synth_1 PF01416.20 PFH35728.1 - 0.019 15.4 0.1 0.02 15.3 0.1 1.1 1 0 0 1 1 1 0 tRNA pseudouridine synthase TMEM65 PF10507.9 PFH35729.1 - 3.2e-35 120.4 2.5 5.9e-35 119.5 2.5 1.4 1 0 0 1 1 1 1 Transmembrane protein 65 GAF PF01590.26 PFH35729.1 - 8.1e-12 45.9 0.0 1.4e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 PFH35729.1 - 0.00032 21.0 0.0 0.017 15.4 0.0 2.6 2 0 0 2 2 2 1 GAF domain LSM PF01423.22 PFH35732.1 - 2.8e-19 68.6 0.5 3.6e-19 68.2 0.5 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 PFH35732.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein PARP PF00644.20 PFH35733.1 - 2.6e-53 180.5 0.0 5.6e-53 179.4 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 PFH35733.1 - 7.6e-37 126.5 0.2 1.6e-36 125.4 0.2 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 PFH35733.1 - 2.5e-10 40.3 0.2 1.3e-09 37.9 0.1 2.4 2 0 0 2 2 2 1 WGR domain PADR1 PF08063.12 PFH35733.1 - 1.3e-06 28.1 0.0 3.3e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 PADR1 (NUC008) domain BRCT PF00533.26 PFH35733.1 - 6.6e-05 23.2 0.0 0.00035 20.9 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-PARP PF00645.18 PFH35733.1 - 0.00015 22.6 0.0 0.00052 20.8 0.0 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Glyco_hydro_17 PF00332.18 PFH35734.1 - 1.8e-27 96.8 0.0 2.6e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Guanylate_cyc PF00211.20 PFH35735.1 - 1.2e-19 70.7 0.0 5.4e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain RRM_1 PF00076.22 PFH35736.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.29 PFH35738.1 - 7.5e-12 45.8 0.0 1.6e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PFH35738.1 - 1.1e-05 25.9 1.1 6.6e-05 23.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PFH35738.1 - 0.00025 21.3 0.2 0.002 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 PFH35738.1 - 0.0038 17.0 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 PFH35738.1 - 0.0052 16.1 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 PFH35738.1 - 0.0058 16.6 0.1 0.04 13.8 0.1 2.4 1 1 0 1 1 1 1 NACHT domain AAA_assoc_2 PF16193.5 PFH35738.1 - 0.0077 16.5 0.1 0.022 15.1 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_5 PF07728.14 PFH35738.1 - 0.0089 16.0 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 PFH35738.1 - 0.42 10.8 0.0 0.42 10.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 PFH35738.1 - 1.6 8.3 8.1 0.42 10.1 1.2 3.0 2 1 0 2 2 2 0 AAA domain Acyltransferase PF01553.21 PFH35739.1 - 9e-10 38.3 0.0 2.7e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase Kinase-like PF14531.6 PFH35740.1 - 8.7e-17 61.4 0.0 1.8e-14 53.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.25 PFH35740.1 - 6.1e-16 58.6 0.0 3e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 PFH35740.1 - 0.0036 16.7 0.2 0.0065 15.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PFH35740.1 - 0.17 11.5 0.0 5 6.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Tho2 PF11262.8 PFH35741.1 - 1.5e-58 198.4 0.0 2e-43 148.7 0.0 2.3 2 0 0 2 2 2 2 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 PFH35741.1 - 3e-24 85.6 0.5 2.2e-11 43.2 0.0 2.8 3 0 0 3 3 3 2 THO complex subunit 2 N-terminus Atg14 PF10186.9 PFH35741.1 - 0.39 9.8 3.3 0.73 8.9 3.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 PFH35742.1 - 0.098 13.3 14.1 0.037 14.6 2.8 2.9 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Leu_zip PF15294.6 PFH35742.1 - 0.21 11.1 7.7 0.41 10.1 7.7 1.4 1 0 0 1 1 1 0 Leucine zipper Prominin PF05478.11 PFH35742.1 - 1 7.2 1.8 2.1 6.2 1.8 1.5 1 0 0 1 1 1 0 Prominin YabA PF06156.13 PFH35742.1 - 1.1 9.9 14.1 0.43 11.2 0.7 3.1 2 1 0 3 3 3 0 Initiation control protein YabA DUF4570 PF15134.6 PFH35742.1 - 1.7 8.7 12.3 0.85 9.7 3.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4570) DUF3450 PF11932.8 PFH35742.1 - 2.2 7.5 15.4 3 7.1 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Tho2 PF11262.8 PFH35742.1 - 4.4 6.4 4.6 8.6 5.5 4.6 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.6 PFH35742.1 - 5.5 6.3 10.8 9.9 5.4 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UTP25 PF06862.12 PFH35745.1 - 6.1e-112 374.8 0.0 5.5e-68 229.9 0.0 3.2 3 0 0 3 3 3 3 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 PFH35745.1 - 0.089 12.6 0.0 7.6 6.3 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase Arginase PF00491.21 PFH35745.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Arginase family EF-hand_7 PF13499.6 PFH35748.1 - 0.00091 19.6 0.1 2.5 8.6 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair AP2 PF00847.20 PFH35750.1 - 4.2e-11 42.9 0.5 1.2e-10 41.5 0.5 1.8 1 0 0 1 1 1 1 AP2 domain G6PD_N PF00479.22 PFH35751.1 - 0.068 13.8 1.0 4.2 8.0 0.0 3.0 3 0 0 3 3 3 0 Glucose-6-phosphate dehydrogenase, NAD binding domain AP_endonuc_2 PF01261.24 PFH35751.1 - 0.11 12.0 0.2 1.6 8.2 0.1 2.3 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel FAST_1 PF06743.15 PFH35752.1 - 3.1 7.8 4.4 13 5.8 0.1 3.2 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 1 PHD PF00628.29 PFH35753.1 - 4.2e-15 55.4 45.5 3.8e-11 42.7 8.9 5.9 5 1 2 7 7 7 3 PHD-finger C1_1 PF00130.22 PFH35753.1 - 0.00055 19.8 2.9 0.00055 19.8 2.9 6.8 4 2 2 6 6 6 3 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 PFH35753.1 - 0.0043 16.6 0.3 0.0043 16.6 0.3 5.9 7 0 0 7 7 7 3 PHD-finger eIF-5_eIF-2B PF01873.17 PFH35754.1 - 1.4e-36 124.9 0.0 2.2e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Vps36-NZF-N PF16988.5 PFH35754.1 - 0.02 14.3 0.6 0.048 13.1 0.1 2.0 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ephrin_rec_like PF07699.13 PFH35754.1 - 0.93 9.3 4.8 14 5.6 0.7 2.3 1 1 1 2 2 2 0 Putative ephrin-receptor like zf-RanBP PF00641.18 PFH35754.1 - 1.1 8.6 5.6 2 7.8 0.4 2.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others MORN PF02493.20 PFH35755.1 - 3.3e-23 80.1 49.9 6.4e-06 25.7 1.2 8.4 8 0 0 8 8 8 7 MORN repeat Hid1 PF12722.7 PFH35756.1 - 1.7e-138 463.2 0.0 1.2e-53 182.5 0.0 4.1 3 1 1 4 4 4 4 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 PFH35756.1 - 1.4e-108 364.1 0.0 1.3e-107 360.9 0.0 2.0 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein PglL_A PF15864.5 PFH35756.1 - 1 9.2 3.4 10 6.0 0.0 3.8 4 0 0 4 4 4 0 Protein glycosylation ligase Fumble PF03630.14 PFH35757.1 - 1.1e-48 166.2 0.0 1.6e-21 76.9 0.0 3.1 3 0 0 3 3 3 3 Fumble Myosin_head PF00063.21 PFH35758.1 - 1.1e-182 608.8 0.2 1.4e-182 608.5 0.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 PFH35758.1 - 0.0036 17.7 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PFH35758.1 - 0.1 12.9 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 PFH35758.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ATP-synt_ab PF00006.25 PFH35758.1 - 0.15 11.7 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain UQ_con PF00179.26 PFH35759.1 - 1.7e-43 147.6 0.0 2.5e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 PFH35759.1 - 8.3e-09 35.2 0.0 2.2e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 UBA/TS-N domain Prok-E2_B PF14461.6 PFH35759.1 - 0.0002 21.1 0.0 0.00036 20.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_4 PF14555.6 PFH35759.1 - 0.033 14.0 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain YflT PF11181.8 PFH35759.1 - 0.052 14.1 0.1 0.088 13.3 0.1 1.4 1 0 0 1 1 1 0 Heat induced stress protein YflT RWD PF05773.22 PFH35759.1 - 0.053 13.8 0.0 0.096 13.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain LSM PF01423.22 PFH35760.1 - 1.1e-05 25.1 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain HSA PF07529.13 PFH35761.1 - 0.012 15.9 0.1 0.049 14.0 0.1 2.0 1 0 0 1 1 1 0 HSA CorA PF01544.18 PFH35762.1 - 0.1 11.9 0.0 1.9 7.8 0.0 2.5 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein PAN_4 PF14295.6 PFH35764.1 - 2.3e-95 312.4 105.7 3.6e-09 36.4 1.6 15.6 15 0 0 15 15 15 15 PAN domain PAN_1 PF00024.26 PFH35764.1 - 1.2e-84 278.3 76.0 3.1e-06 27.1 0.8 15.3 15 0 0 15 15 15 15 PAN domain Pkinase PF00069.25 PFH35766.1 - 1.4e-08 34.4 0.0 2.8e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain CwfJ_C_2 PF04676.14 PFH35768.1 - 1.7e-16 60.9 0.0 4.9e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 PFH35768.1 - 9.3e-14 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Mob_Pre PF01076.19 PFH35768.1 - 0.094 12.5 0.8 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Plasmid recombination enzyme zinc_ribbon_2 PF13240.6 PFH35769.1 - 0.81 9.5 5.3 13 5.7 0.6 2.8 2 0 0 2 2 2 0 zinc-ribbon domain PAN_4 PF14295.6 PFH35770.1 - 5.8e-122 397.5 207.7 2.5e-08 33.7 0.8 26.7 26 0 0 26 26 26 26 PAN domain PAN_1 PF00024.26 PFH35770.1 - 1e-119 390.7 152.6 7.1e-07 29.1 0.1 26.9 26 1 1 27 27 27 26 PAN domain PAN_4 PF14295.6 PFH35771.1 - 1.8e-126 412.0 217.6 2.6e-08 33.7 0.8 27.9 27 0 0 27 27 27 27 PAN domain PAN_1 PF00024.26 PFH35771.1 - 8.9e-124 403.7 164.6 7.3e-07 29.1 0.1 28.1 26 2 2 28 28 28 26 PAN domain NHL PF01436.21 PFH35772.1 - 1.1e-07 31.6 0.1 4.3e-05 23.3 0.1 3.4 2 0 0 2 2 2 1 NHL repeat Ephrin_rec_like PF07699.13 PFH35772.1 - 1.6e-05 24.6 17.8 5.4e-05 22.9 6.4 45.3 31 10 16 49 49 49 26 Putative ephrin-receptor like PAN_4 PF14295.6 PFH35772.1 - 0.00011 22.0 10.0 0.0052 16.7 0.4 3.9 2 0 0 2 2 2 2 PAN domain TNFR_c6 PF00020.18 PFH35772.1 - 0.0087 16.4 0.1 0.0087 16.4 0.1 40.2 37 5 4 41 41 41 11 TNFR/NGFR cysteine-rich region Coronavirus_5 PF05528.11 PFH35772.1 - 0.68 10.0 3.9 25 4.9 0.5 4.0 2 1 1 3 3 3 0 Coronavirus gene 5 protein RFC1 PF08519.12 PFH35773.1 - 1.9e-35 122.3 0.0 3.4e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 PFH35773.1 - 9.4e-11 42.3 0.1 3.1e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 PFH35773.1 - 4.5e-10 39.6 0.0 8.2e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.6 PFH35773.1 - 6.4e-05 22.7 0.5 0.00024 20.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PFH35773.1 - 0.00014 22.1 0.0 0.0032 17.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 PFH35773.1 - 0.00021 21.3 0.1 0.00062 19.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 PFH35773.1 - 0.00041 20.3 0.1 0.32 10.9 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain BRCT PF00533.26 PFH35773.1 - 0.00042 20.6 0.0 0.00096 19.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA_assoc_2 PF16193.5 PFH35773.1 - 0.00044 20.5 0.0 0.0015 18.8 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 PFH35773.1 - 0.0005 20.5 0.3 0.021 15.2 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 PFH35773.1 - 0.0012 19.4 0.0 0.015 15.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 PFH35773.1 - 0.015 15.5 0.0 0.068 13.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 PFH35773.1 - 0.092 12.5 0.1 0.5 10.1 0.0 2.2 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 PFH35773.1 - 0.73 9.6 0.0 0.73 9.6 0.0 3.6 4 1 0 4 4 3 0 AAA domain LtuB PF17455.2 PFH35775.1 - 0.033 14.8 0.1 0.083 13.5 0.1 1.7 1 0 0 1 1 1 0 Late transcription unit B Syntaxin_2 PF14523.6 PFH35775.1 - 0.82 10.1 7.4 1.6 9.1 6.9 1.8 1 1 0 1 1 1 0 Syntaxin-like protein COG2 PF06148.11 PFH35775.1 - 2.4 8.2 6.8 4.7 7.3 1.0 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BshC PF10079.9 PFH35775.1 - 4 6.1 11.3 12 4.5 9.3 2.0 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC AAA_13 PF13166.6 PFH35775.1 - 6.6 5.2 11.9 9.1 4.8 11.9 1.1 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 PFH35775.1 - 6.9 5.6 17.8 3 6.8 11.3 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SET PF00856.28 PFH35775.1 - 7.4 6.9 5.5 14 6.0 5.5 1.6 1 1 0 1 1 1 0 SET domain Sugar_tr PF00083.24 PFH35776.1 - 1.8e-24 86.4 33.9 2.2e-18 66.4 13.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PFH35776.1 - 4.9e-15 55.3 35.7 4.9e-15 55.3 35.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NT-C2 PF10358.9 PFH35778.1 - 0.18 11.6 0.0 0.5 10.1 0.0 1.8 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins Coatomer_WDAD PF04053.14 PFH35779.1 - 2.2e-124 415.9 0.0 3e-124 415.5 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 PFH35779.1 - 1.1e-26 92.6 12.0 1.2e-06 29.1 0.1 8.3 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH35779.1 - 1.4e-06 28.5 0.0 0.97 9.8 0.0 5.5 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 PFH35779.1 - 0.25 11.6 0.9 0.93 9.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Caa3_CtaG PF09678.10 PFH35781.1 - 0.03 13.8 0.2 0.52 9.7 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) PNP_UDP_1 PF01048.20 PFH35782.1 - 4.4e-27 94.9 0.0 6.1e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Pkinase PF00069.25 PFH35785.1 - 2e-43 148.7 0.0 2.1e-27 96.1 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35785.1 - 1.3e-16 60.7 0.0 5.1e-15 55.5 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase UBA_4 PF14555.6 PFH35785.1 - 0.021 14.6 0.1 0.045 13.6 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain DUF3918 PF13056.6 PFH35785.1 - 0.24 11.1 0.5 0.69 9.6 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) zf-HC5HC2H_2 PF13832.6 PFH35788.1 - 2e-35 121.3 32.0 7.6e-26 90.4 8.9 4.9 5 0 0 5 5 5 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PFH35788.1 - 4.4e-17 62.1 18.8 7.1e-10 39.0 9.9 4.7 5 0 0 5 5 5 2 PHD-like zinc-binding domain PHD_2 PF13831.6 PFH35788.1 - 2e-16 59.3 32.4 7.5e-13 47.8 3.0 4.6 4 0 0 4 4 4 2 PHD-finger PHD PF00628.29 PFH35788.1 - 3.4e-05 23.6 9.3 3.4e-05 23.6 9.3 5.8 6 0 0 6 6 6 3 PHD-finger zf-HC5HC2H_2 PF13832.6 PFH35789.1 - 5.2e-14 52.3 7.5 5.2e-14 52.3 7.5 1.9 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.6 PFH35789.1 - 5e-10 38.8 7.2 5e-10 38.8 7.2 2.5 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 PFH35789.1 - 3.1e-07 30.6 5.9 3.1e-07 30.6 5.9 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD PF00628.29 PFH35789.1 - 5.5e-06 26.2 26.4 2.3e-05 24.2 13.7 2.8 2 0 0 2 2 2 2 PHD-finger zf-UDP PF14569.6 PFH35789.1 - 4.2 7.6 11.5 8.9 6.5 5.4 2.7 2 0 0 2 2 2 0 Zinc-binding RING-finger Actin PF00022.19 PFH35791.1 - 8.7e-21 74.0 0.0 1.1e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.19 PFH35792.1 - 6.5e-10 38.2 0.0 1.3e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 Actin W2 PF02020.18 PFH35792.1 - 0.11 12.7 1.0 0.36 11.0 1.0 1.9 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Not3 PF04065.15 PFH35793.1 - 1.2e-12 47.7 8.5 7.3e-10 38.7 8.5 3.2 1 1 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component SH3_1 PF00018.28 PFH35793.1 - 3.1e-06 26.7 0.0 6.5e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 PFH35793.1 - 9.1e-05 22.1 1.4 0.00087 18.9 0.0 3.1 4 0 0 4 4 4 1 Variant SH3 domain SH3_9 PF14604.6 PFH35793.1 - 0.00016 21.5 0.0 0.029 14.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain ANAPC4_WD40 PF12894.7 PFH35794.1 - 6.6e-07 29.5 0.0 2.7 8.3 0.0 5.3 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PFH35794.1 - 6e-05 23.7 0.2 0.77 10.7 0.0 5.0 4 1 1 5 5 5 1 WD domain, G-beta repeat RMI1_N PF08585.12 PFH35796.1 - 6.1e-16 58.8 0.0 5.7e-15 55.7 0.0 2.3 1 1 1 2 2 2 1 RecQ mediated genome instability protein BRCA-2_OB1 PF09103.10 PFH35796.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 IMS PF00817.20 PFH35797.1 - 1.4e-30 106.3 0.0 4.5e-30 104.6 0.0 1.9 1 1 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 PFH35797.1 - 0.014 15.0 0.1 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger adh_short PF00106.25 PFH35798.1 - 3.3e-42 144.2 2.5 6e-42 143.3 2.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PFH35798.1 - 1.5e-34 119.6 3.6 6.4e-34 117.5 3.6 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 PFH35798.1 - 8.8e-34 116.0 0.7 2.1e-16 60.2 0.0 2.6 2 0 0 2 2 2 2 SCP-2 sterol transfer family KR PF08659.10 PFH35798.1 - 2e-18 66.9 2.1 3.7e-18 66.1 2.1 1.4 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.6 PFH35798.1 - 1.8e-06 28.2 0.1 0.055 13.7 0.0 2.9 3 0 0 3 3 3 2 Alkyl sulfatase C-terminal THF_DHG_CYH_C PF02882.19 PFH35798.1 - 0.049 13.0 0.1 0.094 12.0 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UnbV_ASPIC PF07593.12 PFH35799.1 - 0.13 12.3 0.4 18 5.4 0.0 2.8 2 0 0 2 2 2 0 ASPIC and UnbV Amino_oxidase PF01593.24 PFH35800.1 - 1.9e-27 96.7 8.5 1.8e-09 37.4 0.0 4.4 4 0 0 4 4 4 4 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PFH35800.1 - 5.8e-07 29.6 0.8 5.8e-07 29.6 0.8 4.6 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PFH35800.1 - 0.00021 20.1 0.6 0.00032 19.5 0.6 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 PFH35800.1 - 0.00086 19.8 0.3 0.0016 18.9 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PFH35800.1 - 0.0012 18.2 0.2 0.0022 17.3 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 PFH35800.1 - 0.02 13.7 0.4 0.03 13.2 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 PFH35800.1 - 0.47 9.5 3.0 0.78 8.8 3.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Ribosomal_L29e PF01779.17 PFH35801.1 - 4.6e-23 81.2 14.9 5.8e-23 80.9 14.9 1.1 1 0 0 1 1 1 1 Ribosomal L29e protein family Mg_trans_NIPA PF05653.14 PFH35802.1 - 6.9e-16 58.2 13.7 6.9e-16 58.2 13.7 1.9 1 1 1 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 PFH35802.1 - 6.5e-07 29.6 3.9 6.5e-07 29.6 3.9 3.4 2 1 1 3 3 3 1 EamA-like transporter family UPF0060 PF02694.15 PFH35802.1 - 9.2 6.6 13.5 0.16 12.2 2.6 2.7 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family DUF3021 PF11457.8 PFH35803.1 - 0.19 12.1 0.1 0.19 12.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3021) TctA PF01970.16 PFH35803.1 - 0.77 8.4 17.9 0.97 8.1 1.3 3.1 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctA family ThrE PF06738.12 PFH35803.1 - 7.3 5.9 10.4 0.58 9.5 1.6 2.8 3 0 0 3 3 3 0 Putative threonine/serine exporter RRM_1 PF00076.22 PFH35804.1 - 1.6e-29 101.5 1.1 3.3e-15 55.7 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PFH35804.1 - 1.1e-05 25.1 0.0 1.7 8.5 0.0 3.5 3 0 0 3 3 3 3 Occluded RNA-recognition motif DEC-1_N PF04625.13 PFH35804.1 - 8.4 5.3 13.0 13 4.6 13.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ACBP PF00887.19 PFH35805.1 - 5.4e-22 77.8 0.0 1.7e-21 76.2 0.0 1.8 2 0 0 2 2 2 1 Acyl CoA binding protein Ank_5 PF13857.6 PFH35805.1 - 5.5e-21 74.3 4.7 2.2e-12 46.9 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PFH35805.1 - 8.8e-19 67.6 0.7 4.8e-14 52.5 0.1 2.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PFH35805.1 - 1.8e-18 66.9 1.8 3.2e-14 53.3 0.4 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PFH35805.1 - 1.1e-15 57.3 5.3 3e-09 36.9 0.5 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 PFH35805.1 - 7.6e-14 50.5 0.6 2.6e-06 27.3 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat DUF4336 PF14234.6 PFH35805.1 - 0.16 11.1 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) tRNA-synt_2d PF01409.20 PFH35807.1 - 4.6e-86 288.3 0.3 7.6e-86 287.6 0.1 1.4 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 PFH35807.1 - 5.6e-06 26.6 0.2 2e-05 24.8 0.2 2.0 1 0 0 1 1 1 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 PFH35807.1 - 0.00019 21.1 0.0 0.0005 19.8 0.0 1.8 2 0 0 2 2 2 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 PFH35807.1 - 0.00067 19.1 0.0 0.0076 15.7 0.0 2.1 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 PFH35807.1 - 0.0014 17.8 0.9 0.0057 15.8 0.1 2.3 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) TYW3 PF02676.14 PFH35808.1 - 1.1e-46 158.8 0.0 2.2e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase TYW3 Met_10 PF02475.16 PFH35808.1 - 3e-20 72.8 0.0 5.2e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Kelch_5 PF13854.6 PFH35808.1 - 5.4e-11 42.2 0.1 0.00085 19.3 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 PFH35808.1 - 1.2e-09 37.6 0.6 0.0075 15.8 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 PFH35808.1 - 4.3e-08 32.8 3.5 0.23 11.5 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 PFH35808.1 - 3.3e-07 30.2 0.2 0.51 10.4 0.0 4.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 PFH35808.1 - 3.7e-07 30.3 8.2 0.0021 18.3 0.0 5.1 5 0 0 5 5 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 PFH35808.1 - 1.5e-05 25.1 0.4 0.45 10.9 0.0 4.3 4 0 0 4 4 4 2 Kelch motif MTS PF05175.14 PFH35808.1 - 0.002 17.7 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PFH35808.1 - 0.015 16.0 0.0 0.14 12.9 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain DNA_methylase PF00145.17 PFH35808.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase Methyltransf_31 PF13847.6 PFH35808.1 - 0.091 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF4115 PF13464.6 PFH35808.1 - 0.13 12.5 0.0 0.37 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) ARGLU PF15346.6 PFH35809.1 - 0.012 15.5 27.8 0.02 14.8 25.6 2.0 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 VIR_N PF15912.5 PFH35809.1 - 0.045 13.3 6.7 0.082 12.5 6.7 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal DDRGK PF09756.9 PFH35809.1 - 3 7.4 22.3 6 6.4 22.3 1.4 1 0 0 1 1 1 0 DDRGK domain DUF5401 PF17380.2 PFH35809.1 - 3.4 5.6 21.1 5.1 5.1 21.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) zf-RanBP PF00641.18 PFH35810.1 - 4.3e-07 29.1 3.1 4.3e-07 29.1 3.1 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF35_N PF12172.8 PFH35810.1 - 0.0023 17.8 2.9 0.0064 16.4 2.9 1.8 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-tcix PF14952.6 PFH35810.1 - 0.094 12.3 5.7 0.27 10.9 5.7 1.8 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding C1_2 PF03107.16 PFH35810.1 - 0.54 10.6 3.1 1.3 9.4 3.1 1.6 1 0 0 1 1 1 0 C1 domain Ribosomal_S8 PF00410.19 PFH35811.1 - 2.4e-20 72.8 0.0 3.9e-20 72.1 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Aminotran_1_2 PF00155.21 PFH35812.1 - 1.7e-29 103.1 0.0 1.9e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 PFH35812.1 - 5e-09 35.4 0.0 3.9e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Alanine-glyoxylate amino-transferase DUF3523 PF12037.8 PFH35815.1 - 1.5e-76 257.3 29.1 2.5e-76 256.6 29.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 PFH35815.1 - 8.1e-23 81.3 0.0 4.7e-22 78.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PFH35815.1 - 1.1e-05 25.2 0.0 3.3e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PFH35815.1 - 0.00022 21.7 10.9 0.0013 19.2 0.0 3.9 2 2 1 3 3 2 1 AAA ATPase domain AAA_33 PF13671.6 PFH35815.1 - 0.0018 18.4 0.0 0.0018 18.4 0.0 3.1 2 1 0 2 2 1 1 AAA domain AAA_lid_3 PF17862.1 PFH35815.1 - 0.0074 16.1 0.0 0.027 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain Mg_chelatase PF01078.21 PFH35815.1 - 0.012 15.0 0.1 0.054 12.9 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 PFH35815.1 - 0.014 15.5 0.1 0.16 12.1 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 PFH35815.1 - 0.015 15.0 1.5 0.036 13.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 PFH35815.1 - 0.016 15.2 1.6 0.04 13.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 PFH35815.1 - 0.022 14.6 0.0 0.067 13.0 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 PFH35815.1 - 0.023 14.6 0.7 0.42 10.5 0.0 2.9 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 PFH35815.1 - 0.049 14.2 0.0 0.049 14.2 0.0 3.3 2 2 0 2 2 1 0 AAA domain TsaE PF02367.17 PFH35815.1 - 0.057 13.4 0.0 0.057 13.4 0.0 2.7 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 PFH35815.1 - 0.064 13.5 0.0 0.064 13.5 0.0 3.8 2 2 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 PFH35815.1 - 0.082 13.3 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.25 PFH35815.1 - 0.11 12.1 0.2 0.62 9.7 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 PFH35815.1 - 0.16 11.3 0.0 0.16 11.3 0.0 3.3 4 0 0 4 4 4 0 FtsK/SpoIIIE family V_ATPase_I PF01496.19 PFH35815.1 - 0.71 7.7 11.5 1 7.2 11.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_25 PF13481.6 PFH35815.1 - 1.7 8.2 6.5 0.78 9.3 0.1 3.1 2 1 1 3 3 3 0 AAA domain TFIIA PF03153.13 PFH35815.1 - 7 6.5 22.1 9.9 6.0 22.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MS_channel PF00924.18 PFH35816.1 - 3e-16 59.6 3.0 4.6e-16 59.0 3.0 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EI24 PF07264.11 PFH35817.1 - 3.3e-10 40.5 29.7 2.7e-05 24.5 1.3 3.8 3 1 0 3 3 3 3 Etoposide-induced protein 2.4 (EI24) ParD_antitoxin PF03693.14 PFH35819.1 - 0.051 14.0 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH SAG PF04092.13 PFH35821.1 - 1e-08 36.0 0.6 1.4e-08 35.6 0.6 1.2 1 0 0 1 1 1 1 SRS domain Topoisom_I PF01028.20 PFH35822.1 - 7.6e-105 349.3 6.7 1.7e-104 348.1 6.7 1.6 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 PFH35822.1 - 7.8e-88 293.5 0.2 7.8e-88 293.5 0.2 2.5 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 PFH35822.1 - 2.6e-31 107.4 0.5 8.7e-31 105.7 0.5 1.9 1 0 0 1 1 1 1 C-terminal topoisomerase domain Hydrolase_6 PF13344.6 PFH35822.1 - 0.042 14.0 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Abhydrolase_1 PF00561.20 PFH35823.1 - 1.8e-08 34.4 0.4 0.042 13.5 0.1 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PFH35823.1 - 1.9e-07 31.9 23.8 0.00021 22.0 10.7 3.6 3 1 0 3 3 3 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PFH35823.1 - 4e-05 23.0 0.0 0.17 11.1 0.0 2.8 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Esterase PF00756.20 PFH35823.1 - 0.0018 18.0 0.2 0.0053 16.4 0.3 1.6 2 0 0 2 2 2 1 Putative esterase PGAP1 PF07819.13 PFH35823.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein PP28 PF10252.9 PFH35825.1 - 6.8e-17 61.7 20.7 6.8e-17 61.7 20.7 2.5 1 1 1 2 2 2 1 Casein kinase substrate phosphoprotein PP28 DUF4611 PF15387.6 PFH35825.1 - 0.0075 16.5 12.7 0.58 10.4 5.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 PFH35825.1 - 0.37 8.8 11.5 0.35 8.9 11.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sin_N PF04801.13 PFH35825.1 - 0.42 9.8 10.2 0.51 9.5 10.2 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region SpoIIIAH PF12685.7 PFH35825.1 - 3.5 7.4 10.0 4.8 7.0 10.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein CDC45 PF02724.14 PFH35825.1 - 6.3 5.0 19.0 8.1 4.6 19.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 PFH35825.1 - 7.9 4.9 23.2 4.6 5.7 21.6 1.3 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-B_dimeris PF09026.10 PFH35825.1 - 8.4 6.9 14.2 13 6.2 7.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain A_deaminase PF00962.22 PFH35827.1 - 3.6e-98 328.9 0.0 5.2e-98 328.4 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase YuzL PF14115.6 PFH35827.1 - 1 9.9 3.0 2.8 8.5 3.0 1.8 1 0 0 1 1 1 0 YuzL-like protein SHMT PF00464.19 PFH35834.1 - 2.2e-174 579.7 0.0 2.7e-174 579.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase CoA_transf_3 PF02515.17 PFH35834.1 - 0.16 11.1 0.0 0.35 9.9 0.0 1.5 2 0 0 2 2 2 0 CoA-transferase family III Beta_elim_lyase PF01212.21 PFH35834.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase FixS PF03597.15 PFH35836.1 - 3.6e-16 58.6 19.1 6.1 6.6 0.0 11.0 9 0 0 9 9 9 9 Cytochrome oxidase maturation protein cbb3-type DUF3197 PF11432.8 PFH35836.1 - 0.00028 20.7 26.3 46 3.9 0.1 9.2 9 0 0 9 9 9 0 Protein of unknown function (DUF3197) PIF2 PF04631.12 PFH35836.1 - 0.00078 18.4 0.0 2.1e+02 0.5 0.0 7.0 8 0 0 8 8 8 0 Per os infectivity factor 2 DUF287 PF03384.14 PFH35836.1 - 0.0085 16.5 39.0 51 4.4 0.1 9.6 9 0 0 9 9 9 0 Drosophila protein of unknown function, DUF287 FixS PF03597.15 PFH35837.1 - 1.5e-23 82.2 37.2 9.4 6.0 0.0 17.0 15 0 0 15 15 15 15 Cytochrome oxidase maturation protein cbb3-type DUF3197 PF11432.8 PFH35837.1 - 0.00026 20.9 46.3 72 3.3 0.1 13.9 14 0 0 14 14 14 0 Protein of unknown function (DUF3197) DUF287 PF03384.14 PFH35837.1 - 0.028 14.8 68.7 79 3.8 0.1 15.4 15 0 0 15 15 15 0 Drosophila protein of unknown function, DUF287 Sporozoite_P67 PF05642.11 PFH35838.1 - 0.056 11.5 1.2 0.073 11.2 1.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen gpW PF02831.15 PFH35838.1 - 0.19 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 gpW PKcGMP_CC PF16808.5 PFH35838.1 - 0.19 11.6 0.3 0.3 11.0 0.3 1.2 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase KLRAQ PF10205.9 PFH35839.1 - 0.019 15.2 7.1 2.3 8.5 0.2 2.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein JIP_LZII PF16471.5 PFH35839.1 - 0.17 12.1 8.0 0.071 13.3 1.3 2.9 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF3357 PF11837.8 PFH35839.1 - 0.25 11.8 0.0 0.25 11.8 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3357) DUF997 PF06196.12 PFH35839.1 - 1.6 8.8 4.6 0.43 10.6 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF997) TMCO5 PF14992.6 PFH35839.1 - 2.1 7.9 7.0 17 4.8 0.0 2.9 3 0 0 3 3 3 0 TMCO5 family Seryl_tRNA_N PF02403.22 PFH35839.1 - 7.6 6.8 10.8 0.76 10.0 1.0 3.3 2 2 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4164 PF13747.6 PFH35839.1 - 8.4 6.7 15.0 0.85 9.9 4.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Ribosomal_L18p PF00861.22 PFH35840.1 - 1.2e-23 83.7 3.4 7.2e-23 81.2 3.4 1.9 1 1 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast RAP PF08373.10 PFH35841.1 - 3.7e-08 33.4 0.0 2.7e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 RAP domain DUF5092 PF17010.5 PFH35842.1 - 0.061 13.2 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5092) Kinesin PF00225.23 PFH35843.1 - 3.5e-88 295.7 0.0 3.1e-87 292.6 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PFH35843.1 - 9e-22 77.6 0.0 1.6e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding HasA PF06438.12 PFH35843.1 - 0.00012 21.8 22.7 11 5.5 0.2 6.6 6 0 0 6 6 6 6 Heme-binding protein A (HasA) PSD5 PF07637.11 PFH35843.1 - 0.05 14.0 15.4 2.2e+02 2.3 0.1 8.5 7 0 0 7 7 7 0 Protein of unknown function (DUF1595) HECT PF00632.25 PFH35843.1 - 0.066 12.7 17.1 35 3.7 0.0 7.0 7 0 0 7 7 7 0 HECT-domain (ubiquitin-transferase) FAM176 PF14851.6 PFH35845.1 - 0.0021 17.7 0.3 0.0056 16.4 0.3 1.6 1 0 0 1 1 1 1 FAM176 family UPF0242 PF06785.11 PFH35845.1 - 0.029 14.5 0.1 0.053 13.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 PFH35845.1 - 0.034 13.9 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator EphA2_TM PF14575.6 PFH35845.1 - 0.72 10.8 2.6 0.49 11.3 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TPH PF13868.6 PFH35846.1 - 2.9e-52 177.3 161.9 2.9e-52 177.3 161.9 2.6 2 1 1 3 3 3 1 Trichohyalin-plectin-homology domain ThiF PF00899.21 PFH35848.1 - 9.2e-52 175.8 0.0 1.4e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 ThiF family Cupin_8 PF13621.6 PFH35849.1 - 5.9e-31 108.1 0.0 1.2e-30 107.1 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 PFH35849.1 - 1.6e-05 24.6 0.0 0.0032 17.0 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein DUF3336 PF11815.8 PFH35850.1 - 1.4e-28 99.4 1.2 2.2e-28 98.7 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 PFH35850.1 - 8.4e-19 68.6 0.0 2.1e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase PrmA PF06325.13 PFH35851.1 - 0.026 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MIP PF00230.20 PFH35852.1 - 1.4e-13 51.1 2.5 1.9e-13 50.7 2.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein COG4 PF08318.12 PFH35855.1 - 4.6e-23 81.8 0.0 3.7e-19 69.0 0.0 3.3 3 1 1 4 4 4 2 COG4 transport protein zf-C4H2 PF10146.9 PFH35855.1 - 0.02 15.2 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein Sec6 PF06046.13 PFH35855.1 - 0.05 12.0 0.0 0.43 8.9 0.0 2.4 3 0 0 3 3 3 0 Exocyst complex component Sec6 CENP-F_leu_zip PF10473.9 PFH35855.1 - 2.9 7.9 9.2 23 5.0 5.6 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GIY-YIG PF01541.24 PFH35857.1 - 7.1e-11 42.2 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FYVE PF01363.21 PFH35857.1 - 0.4 10.9 4.6 0.72 10.0 0.3 2.5 2 0 0 2 2 2 0 FYVE zinc finger C1_1 PF00130.22 PFH35857.1 - 0.99 9.3 2.8 0.63 10.0 0.6 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Oxysterol_BP PF01237.18 PFH35858.1 - 0.098 11.5 1.1 0.16 10.8 1.1 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein DDRGK PF09756.9 PFH35858.1 - 4.7 6.8 10.2 0.058 13.0 2.9 1.4 2 0 0 2 2 2 0 DDRGK domain RRM_1 PF00076.22 PFH35859.1 - 1.3e-12 47.3 0.0 4.4e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mg_trans_NIPA PF05653.14 PFH35861.1 - 5.6e-23 81.5 13.5 7.6e-13 48.2 6.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 PFH35861.1 - 0.00038 20.7 8.8 0.00038 20.7 8.8 3.5 2 2 1 3 3 3 1 EamA-like transporter family DUF2387 PF09526.10 PFH35863.1 - 2.7 8.2 11.9 14 5.9 0.7 3.9 4 0 0 4 4 4 0 Probable metal-binding protein (DUF2387) DUF1364 PF07102.12 PFH35863.1 - 4.8 7.1 11.1 0.43 10.5 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1364) Torus PF16131.5 PFH35864.1 - 2.7 8.7 8.7 0.19 12.5 0.8 2.3 2 0 0 2 2 2 0 Torus domain zf_CCCH_4 PF18345.1 PFH35864.1 - 8.5 6.6 10.2 3.7 7.7 5.5 2.6 3 0 0 3 3 3 0 Zinc finger domain Tubulin PF00091.25 PFH35865.1 - 1.6e-69 234.1 0.0 5.1e-69 232.4 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PFH35865.1 - 9.6e-42 142.1 0.1 1.4e-41 141.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PFH35865.1 - 0.00023 21.5 0.0 0.00054 20.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 PFH35865.1 - 0.0066 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 PFH35865.1 - 0.015 14.5 0.1 0.031 13.5 0.0 1.5 2 0 0 2 2 2 0 Tubulin like MKT1_C PF12246.8 PFH35866.1 - 2.9e-52 177.3 0.0 3.9e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 PFH35866.1 - 2.9e-20 72.4 0.0 6.4e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.18 PFH35866.1 - 1.8e-06 28.2 0.0 3.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 PFH35866.1 - 0.00015 22.1 0.0 0.00031 21.2 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain Auto_anti-p27 PF06677.12 PFH35867.1 - 2.1e-16 59.8 1.8 3.7e-16 59.0 1.8 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribosomal_S19e PF01090.19 PFH35869.1 - 7.3e-57 190.9 0.0 8.3e-57 190.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.10 PFH35869.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Tweety PF04906.13 PFH35870.1 - 0.01 14.6 1.2 0.01 14.6 1.2 1.6 1 1 0 1 1 1 1 Tweety SKA2 PF16740.5 PFH35870.1 - 0.011 15.5 1.5 0.011 15.5 1.5 2.7 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Not3 PF04065.15 PFH35870.1 - 0.04 13.4 7.7 0.027 13.9 2.1 2.2 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Penicil_amidase PF01804.18 PFH35870.1 - 0.23 10.4 3.0 0.29 10.1 3.0 1.1 1 0 0 1 1 1 0 Penicillin amidase DNA_ligase_A_N PF04675.14 PFH35870.1 - 0.29 11.5 3.9 1.6 9.0 3.9 2.1 1 1 0 1 1 1 0 DNA ligase N terminus Mod_r PF07200.13 PFH35870.1 - 0.32 11.1 11.7 1.9 8.6 4.3 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 PFH35870.1 - 0.83 9.7 7.1 2.3 8.3 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phasin PF05597.11 PFH35870.1 - 1 9.4 10.5 0.16 12.0 2.8 2.4 1 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 PFH35870.1 - 1.9 8.6 10.9 5.1 7.1 1.3 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GP41 PF00517.17 PFH35870.1 - 4.6 7.1 6.0 3.1 7.6 1.2 2.4 2 1 0 2 2 2 0 Retroviral envelope protein ATP-synt_C PF00137.21 PFH35871.1 - 6e-33 113.0 33.5 3.9e-20 72.0 13.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Tachykinin PF02202.16 PFH35871.1 - 0.75 9.9 3.8 7.9 6.7 0.5 3.3 2 0 0 2 2 2 0 Tachykinin family WD40 PF00400.32 PFH35872.1 - 0.00014 22.6 0.9 0.13 13.2 0.0 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat FAST_1 PF06743.15 PFH35873.1 - 0.18 11.8 0.0 27 4.8 0.0 2.8 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Sec63 PF02889.16 PFH35874.1 - 4.6e-151 501.2 0.0 4.9e-86 288.1 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 PFH35874.1 - 1.1e-37 129.5 0.4 4.9e-25 88.3 0.2 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 PFH35874.1 - 4.1e-33 113.9 1.0 1.8e-32 111.8 1.0 2.2 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 PFH35874.1 - 1.3e-15 57.9 0.0 1.7e-13 50.9 0.1 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PFH35874.1 - 8.1e-13 48.7 0.1 1.4e-07 31.8 0.0 4.4 4 2 0 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 PFH35874.1 - 0.013 15.8 4.0 0.13 12.6 0.1 3.9 4 1 0 4 4 4 0 AAA domain AAA PF00004.29 PFH35874.1 - 0.083 13.3 0.0 0.39 11.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SAPS PF04499.15 PFH35875.1 - 3.8 6.2 7.3 4.6 5.9 7.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 PFH35875.1 - 5.1 6.4 16.0 5.9 6.2 16.0 1.1 1 0 0 1 1 1 0 SDA1 IF4E PF01652.18 PFH35876.1 - 1.3e-35 122.6 0.1 1.7e-35 122.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DnaJ PF00226.31 PFH35877.1 - 6.6e-11 42.2 0.0 3.8e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 DnaJ domain zf-CSL PF05207.13 PFH35877.1 - 0.031 14.0 4.7 3.2 7.6 0.1 2.5 2 0 0 2 2 2 0 CSL zinc finger Eapp_C PF10238.9 PFH35877.1 - 5 7.2 5.8 0.8 9.8 0.7 2.0 1 1 0 2 2 2 0 E2F-associated phosphoprotein F5_F8_type_C PF00754.25 PFH35878.1 - 0.014 15.5 0.2 0.04 14.0 0.2 1.7 1 0 0 1 1 1 0 F5/8 type C domain DEAD PF00270.29 PFH35879.1 - 3.8e-22 78.9 0.0 5.1e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH35879.1 - 3.4e-14 53.1 0.0 9.6e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH35879.1 - 0.088 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit F5_F8_type_C PF00754.25 PFH35880.1 - 0.0021 18.2 0.1 0.0052 16.9 0.1 1.7 1 0 0 1 1 1 1 F5/8 type C domain UCH PF00443.29 PFH35881.1 - 1.8e-17 63.7 0.0 2.2e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PFH35881.1 - 0.13 11.8 0.3 0.4 10.2 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 PFH35882.1 - 8.6e-16 58.2 0.0 1.4e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TSP_1 PF00090.19 PFH35883.1 - 3.6e-106 347.2 217.8 3.3e-10 40.0 4.0 21.9 20 1 0 20 20 20 17 Thrombospondin type 1 domain Notch PF00066.17 PFH35883.1 - 2.2e-19 69.6 107.2 4.9e-07 30.1 13.9 9.0 7 0 0 7 7 7 4 LNR domain B PF02216.16 PFH35884.1 - 0.11 12.5 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 B domain F-box-like PF12937.7 PFH35885.1 - 0.068 13.1 0.4 0.16 11.9 0.4 1.6 1 0 0 1 1 1 0 F-box-like Defensin_4 PF07936.12 PFH35885.1 - 0.14 12.1 0.1 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 Potassium-channel blocking toxin Cgr1 PF03879.14 PFH35886.1 - 8.3e-06 26.1 27.4 8.3e-06 26.1 27.4 1.9 2 0 0 2 2 2 1 Cgr1 family RAG1_imp_bd PF12560.8 PFH35886.1 - 1.4 8.4 11.7 0.76 9.3 0.2 2.3 2 0 0 2 2 2 0 RAG1 importin binding Peptidase_S64 PF08192.11 PFH35886.1 - 5.6 5.3 8.4 7 5.0 8.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Hydrolase_4 PF12146.8 PFH35888.1 - 1.7e-08 34.1 0.1 4e-06 26.3 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PFH35888.1 - 1.7e-06 28.8 0.0 3.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PFH35888.1 - 1.2e-05 25.1 0.7 0.0027 17.4 0.2 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.12 PFH35888.1 - 0.0003 19.8 0.2 0.00046 19.2 0.2 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 PFH35888.1 - 0.0023 17.7 0.0 0.028 14.2 0.0 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 PFH35888.1 - 0.0089 15.5 0.0 0.058 12.9 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family EF-hand_7 PF13499.6 PFH35889.1 - 0.00024 21.5 0.2 0.061 13.8 0.4 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 PFH35889.1 - 0.00031 20.1 0.1 0.33 10.6 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PFH35889.1 - 0.007 16.2 0.3 4.3 7.5 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain Mlo PF03094.15 PFH35889.1 - 0.014 13.8 0.4 0.014 13.8 0.4 2.9 1 1 0 3 3 3 0 Mlo family RAMP4 PF06624.12 PFH35889.1 - 0.34 11.0 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 HemY_N PF07219.13 PFH35889.1 - 0.58 10.4 0.0 0.58 10.4 0.0 3.3 4 0 0 4 4 4 0 HemY protein N-terminus Phage_holin_3_6 PF07332.11 PFH35889.1 - 1.2 9.3 10.8 1.3 9.0 0.3 3.4 3 1 1 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III MOZART1 PF12554.8 PFH35890.1 - 4.8e-24 83.9 1.1 6.1e-24 83.6 1.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated IBN_N PF03810.19 PFH35891.1 - 1.6e-10 40.7 0.0 9.1e-10 38.3 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 PFH35891.1 - 1.8e-08 33.6 0.1 7.3e-07 28.3 0.0 2.8 3 0 0 3 3 3 1 Cse1 FYDLN_acid PF09538.10 PFH35891.1 - 0.23 12.2 9.5 0.62 10.8 9.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Sporozoite_P67 PF05642.11 PFH35891.1 - 0.26 9.3 0.6 0.54 8.3 0.6 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 PFH35891.1 - 2 6.4 17.8 1.3 7.0 15.2 1.9 2 0 0 2 2 2 0 DNA polymerase phi ALF PF03752.13 PFH35892.1 - 0.069 13.1 0.3 0.22 11.5 0.3 1.9 1 1 0 1 1 1 0 Short repeats of unknown function DUF4131 PF13567.6 PFH35892.1 - 0.19 11.3 10.4 4.3 6.9 0.3 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) DUF3357 PF11837.8 PFH35892.1 - 0.2 12.1 1.5 23 5.5 0.0 3.2 4 1 0 4 4 4 0 Domain of unknown function (DUF3357) Ni_hydr_CYTB PF01292.20 PFH35892.1 - 0.32 10.6 2.7 0.92 9.1 0.0 2.5 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 DUF4500 PF14937.6 PFH35893.1 - 0.2 11.7 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) DUF4381 PF14316.6 PFH35893.1 - 0.42 10.8 4.2 6.6 7.0 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF4131 PF13567.6 PFH35893.1 - 0.53 9.9 5.8 2.2 7.9 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) NUFIP1 PF10453.9 PFH35894.1 - 0.00017 21.3 0.1 0.00035 20.4 0.1 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.8 PFH35894.1 - 4.5 7.7 7.3 0.14 12.5 0.7 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3522 PF12036.8 PFH35895.1 - 2.3e-12 47.6 11.2 3.5e-12 47.0 11.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DUF664 PF04978.12 PFH35895.1 - 0.0054 17.1 1.8 0.089 13.2 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF664) Med4 PF10018.9 PFH35896.1 - 0.0034 17.1 0.0 0.0034 17.1 0.0 2.3 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Proteasome PF00227.26 PFH35897.1 - 3.2e-46 157.2 2.2 3.8e-46 157.0 2.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Autoind_bind PF03472.15 PFH35899.1 - 0.067 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Autoinducer binding domain V-SNARE_C PF12352.8 PFH35901.1 - 3.2e-11 43.3 0.8 9.3e-11 41.9 0.8 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 PFH35901.1 - 0.00014 21.7 0.1 0.00033 20.5 0.1 1.5 1 0 0 1 1 1 1 Sec20 Eapp_C PF10238.9 PFH35902.1 - 1.2e-45 155.2 0.8 1.2e-45 155.2 0.8 2.4 3 0 0 3 3 3 1 E2F-associated phosphoprotein RabGAP-TBC PF00566.18 PFH35903.1 - 3.7e-08 33.3 0.2 0.051 13.2 0.0 3.6 4 0 0 4 4 4 3 Rab-GTPase-TBC domain Ribosomal_L4 PF00573.22 PFH35905.1 - 8.3e-45 152.8 0.0 1.4e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family zf-LYAR PF08790.11 PFH35906.1 - 3.2e-12 46.1 10.0 7e-11 41.8 5.0 2.3 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf-ACC PF17848.1 PFH35906.1 - 0.19 11.8 0.4 0.19 11.8 0.4 1.7 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-C2H2_4 PF13894.6 PFH35906.1 - 0.24 12.4 2.1 23 6.2 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-TRAF PF02176.18 PFH35906.1 - 0.56 11.0 4.6 1.6 9.5 2.7 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger LIM PF00412.22 PFH35906.1 - 1.6 9.0 9.2 3.4 8.0 6.5 2.5 1 1 1 2 2 2 0 LIM domain Inositol_P PF00459.25 PFH35907.1 - 4e-41 141.3 0.0 5.1e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 PFH35907.1 - 0.012 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain ubiquitin PF00240.23 PFH35908.1 - 5e-21 74.2 0.1 7.6e-21 73.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PFH35908.1 - 1e-06 28.5 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 PFH35908.1 - 3.3e-06 26.9 0.1 3.3e-06 26.9 0.1 2.0 2 0 0 2 2 1 1 UBA/TS-N domain HOIP-UBA PF16678.5 PFH35908.1 - 0.0032 17.5 1.0 0.0063 16.5 0.0 2.0 3 0 0 3 3 3 1 HOIP UBA domain pair CUE PF02845.16 PFH35908.1 - 0.0049 16.6 0.4 0.016 14.9 0.0 2.2 2 0 0 2 2 2 1 CUE domain TBK1_ULD PF18396.1 PFH35908.1 - 0.0077 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain XPC-binding PF09280.11 PFH35908.1 - 0.014 15.2 2.1 0.014 15.2 2.1 4.0 2 1 1 3 3 3 0 XPC-binding domain Ubiquitin_2 PF14560.6 PFH35908.1 - 0.033 14.6 0.1 0.093 13.2 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 PFH35908.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PFH35908.1 - 0.14 12.8 0.1 0.38 11.3 0.0 1.8 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain E3_UbLigase_EDD PF11547.8 PFH35908.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD TetR_C_20 PF17925.1 PFH35908.1 - 1.4 9.3 7.9 3.9 7.8 0.7 3.2 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain RNA_pol_3_Rpc31 PF11705.8 PFH35909.1 - 6.2e-13 49.5 2.9 8.8e-13 49.0 2.9 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 FYDLN_acid PF09538.10 PFH35909.1 - 5.6 7.7 11.7 12 6.6 11.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) LCCL PF03815.19 PFH35910.1 - 1.5e-23 82.7 0.4 5.5e-23 80.9 0.4 2.0 1 0 0 1 1 1 1 LCCL domain F5_F8_type_C PF00754.25 PFH35910.1 - 1.5e-14 54.2 0.8 2.5e-12 47.0 0.1 2.5 2 0 0 2 2 2 2 F5/8 type C domain Ricin_B_lectin PF00652.22 PFH35910.1 - 3.6e-07 30.5 0.0 8.9e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain COLFI PF01410.18 PFH35910.1 - 1.2e-05 24.8 0.1 2.3e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Fibrinogen_C PF00147.18 PFH35910.1 - 0.12 12.1 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain NARP1 PF12569.8 PFH35911.1 - 5e-119 398.6 25.1 3.4e-85 286.9 16.2 4.9 4 1 0 4 4 4 3 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 PFH35911.1 - 4.4e-12 45.1 25.2 3e-05 23.8 0.0 8.9 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 PFH35911.1 - 4e-09 36.0 6.4 0.046 13.9 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 PFH35911.1 - 1.4e-08 34.9 18.2 4.6 8.3 0.0 10.4 10 2 3 13 13 11 3 Tetratricopeptide repeat TPR_16 PF13432.6 PFH35911.1 - 1.5e-05 25.5 11.6 0.52 11.0 0.4 6.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 PFH35911.1 - 8.2e-05 22.7 7.1 0.2 12.1 0.0 6.4 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 PFH35911.1 - 0.0008 19.0 0.0 0.06 13.0 0.0 3.0 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 PFH35911.1 - 0.00099 18.8 9.1 0.011 15.5 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH35911.1 - 0.0011 19.1 17.6 0.084 13.1 0.6 4.9 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PFH35911.1 - 0.0046 17.5 10.0 16 6.1 1.7 6.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 PFH35911.1 - 0.0057 16.9 16.8 1.2 9.5 0.0 6.3 5 2 1 6 6 6 2 Tetratricopeptide repeat DUF4303 PF14136.6 PFH35911.1 - 0.027 14.2 0.0 0.093 12.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) DUF3323 PF11796.8 PFH35911.1 - 0.12 12.2 0.2 0.12 12.2 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function N-terminus (DUF3323) TPR_6 PF13174.6 PFH35911.1 - 8.2 7.3 10.4 42 5.1 0.3 5.8 7 0 0 7 7 5 0 Tetratricopeptide repeat Leu_zip PF15294.6 PFH35913.1 - 0.0025 17.4 20.1 0.0025 17.4 20.1 6.4 2 1 4 6 6 6 1 Leucine zipper HALZ PF02183.18 PFH35913.1 - 0.0057 16.9 2.0 0.0057 16.9 2.0 10.8 10 2 1 11 11 11 2 Homeobox associated leucine zipper DivIC PF04977.15 PFH35913.1 - 0.015 15.1 8.3 0.015 15.1 8.3 11.9 6 4 5 12 12 12 0 Septum formation initiator UNC45-central PF11701.8 PFH35916.1 - 0.5 10.3 10.6 17 5.3 1.5 3.8 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Arm PF00514.23 PFH35916.1 - 7.2 6.8 8.6 7.6 6.7 0.2 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Folate_rec PF03024.14 PFH35918.1 - 2.4e-16 60.1 3.1 4e-16 59.4 3.1 1.3 1 0 0 1 1 1 1 Folate receptor family FSAP_sig_propep PF03032.15 PFH35918.1 - 0.088 12.9 0.2 0.088 12.9 0.2 4.3 5 0 0 5 5 5 0 Frog skin active peptide family signal and propeptide CBP_BcsF PF11120.8 PFH35918.1 - 6.9 6.9 6.8 6.8 6.9 2.2 2.5 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF Mg_trans_NIPA PF05653.14 PFH35919.1 - 0.00036 19.8 10.1 0.0027 16.9 5.3 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA DUF667 PF05018.13 PFH35921.1 - 6.3e-93 309.7 0.7 7e-93 309.5 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) W2 PF02020.18 PFH35924.1 - 0.012 15.7 1.8 0.012 15.7 1.8 3.0 3 0 0 3 3 3 0 eIF4-gamma/eIF5/eIF2-epsilon AlaDh_PNT_C PF01262.21 PFH35925.1 - 1.8e-73 246.4 0.1 2.3e-73 246.1 0.1 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 PFH35925.1 - 8.3e-40 136.2 0.0 1.4e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 PFH35925.1 - 1e-06 28.3 0.0 4.8e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 PFH35925.1 - 4.5e-05 22.7 0.2 6.2e-05 22.3 0.2 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 PFH35925.1 - 0.00023 20.5 0.1 0.00042 19.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 PFH35925.1 - 0.00039 20.5 0.0 0.00063 19.8 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 PFH35925.1 - 0.0016 18.3 0.1 0.0032 17.4 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 PFH35925.1 - 0.002 18.7 0.1 0.0036 17.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.21 PFH35925.1 - 0.0031 17.6 0.1 0.012 15.6 0.1 1.9 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 PFH35925.1 - 0.0043 17.3 0.0 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 PFH35925.1 - 0.005 17.3 0.1 0.0092 16.4 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 PFH35925.1 - 0.0058 16.2 0.1 0.0098 15.5 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 PFH35925.1 - 0.01 15.0 3.1 0.015 14.4 3.1 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 PFH35925.1 - 0.012 15.2 2.4 0.03 13.9 2.4 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase F420_oxidored PF03807.17 PFH35925.1 - 0.017 15.7 0.4 0.14 12.7 0.1 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.14 PFH35925.1 - 0.037 12.7 1.4 0.05 12.3 1.4 1.1 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 PFH35925.1 - 0.038 14.2 3.3 0.091 13.0 1.4 2.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.15 PFH35925.1 - 0.041 14.1 0.4 0.12 12.5 0.0 2.0 3 0 0 3 3 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase MtrD PF04207.12 PFH35925.1 - 0.065 12.9 2.8 0.14 11.9 2.8 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D FAD_oxidored PF12831.7 PFH35925.1 - 0.08 12.3 6.7 0.12 11.7 6.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UPF0160 PF03690.13 PFH35926.1 - 8e-102 341.1 0.0 3.7e-67 227.2 0.0 2.0 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0160) LMF1 PF06762.14 PFH35929.1 - 9.3e-146 486.4 7.9 2.9e-145 484.8 7.9 1.7 1 1 0 1 1 1 1 Lipase maturation factor LMF1 PF06762.14 PFH35930.1 - 2.6e-142 475.0 9.7 4.1e-142 474.4 9.7 1.3 1 0 0 1 1 1 1 Lipase maturation factor Pkinase PF00069.25 PFH35931.1 - 4.7e-72 242.5 0.0 6.4e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35931.1 - 1.3e-31 109.8 0.0 2e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH35931.1 - 0.0018 18.3 0.0 0.01 15.8 0.0 2.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PFH35931.1 - 0.013 14.3 3.3 0.013 14.3 0.0 2.5 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 PFH35931.1 - 0.023 14.1 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bradykinin PF06753.12 PFH35931.1 - 2.5 7.9 6.4 2 8.2 2.0 2.9 2 0 0 2 2 2 0 Bradykinin SepSecS PF05889.13 PFH35932.1 - 3.8e-113 378.1 0.0 7.5e-108 360.7 0.0 3.0 3 0 0 3 3 3 3 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 PFH35932.1 - 0.00047 19.5 0.0 0.00072 18.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase CC2D2AN-C2 PF15625.6 PFH35933.1 - 0.011 15.5 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain NT-C2 PF10358.9 PFH35933.1 - 0.043 13.6 0.2 0.083 12.6 0.2 1.5 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins IF4E PF01652.18 PFH35934.1 - 1.6e-27 96.3 0.0 2.3e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PPP4R2 PF09184.11 PFH35934.1 - 0.0038 16.9 1.8 0.0038 16.9 1.8 2.3 2 0 0 2 2 2 1 PPP4R2 WD40 PF00400.32 PFH35935.1 - 6.9e-06 26.7 5.5 0.01 16.7 0.3 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH35935.1 - 0.044 14.1 0.2 30 5.0 0.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PCMT PF01135.19 PFH35936.1 - 3.6e-60 203.3 0.2 6.5e-56 189.4 0.0 2.2 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 PFH35936.1 - 0.002 17.9 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH35936.1 - 0.031 15.0 0.0 0.11 13.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 PFH35936.1 - 0.17 11.3 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 PFH35936.1 - 0.23 10.7 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 PFH35936.1 - 0.25 10.9 0.0 0.41 10.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TFIID_30kDa PF03540.13 PFH35939.1 - 1e-05 25.4 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Sec16_N PF12935.7 PFH35939.1 - 0.035 14.3 0.2 0.058 13.6 0.2 1.3 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus Prefoldin PF02996.17 PFH35940.1 - 2.1e-25 89.0 3.1 2.7e-25 88.6 3.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 PFH35940.1 - 0.0017 18.3 8.3 0.024 14.6 5.4 2.3 1 1 0 2 2 2 1 Prefoldin subunit GAS PF13851.6 PFH35940.1 - 0.29 10.4 11.2 0.74 9.1 7.5 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DHR10 PF18595.1 PFH35940.1 - 0.6 10.2 11.1 0.73 9.9 0.7 2.3 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain SKA1 PF07160.12 PFH35940.1 - 0.64 9.8 7.9 0.15 11.9 3.7 1.9 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 Spc24 PF08286.11 PFH35940.1 - 7.9 6.8 7.3 28 5.0 0.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FBPase PF00316.20 PFH35943.1 - 1.3e-38 132.4 0.2 1.8e-38 131.9 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Sigma70_ner PF04546.13 PFH35943.1 - 0.095 12.6 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region SNF2_N PF00176.23 PFH35946.1 - 7.3e-48 163.1 0.1 2.3e-47 161.4 0.0 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PFH35946.1 - 8.2e-17 61.6 0.0 7.9e-15 55.2 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH35946.1 - 1.9e-08 34.5 0.0 3.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PFH35946.1 - 4e-07 30.0 0.0 6.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2439 PF10382.9 PFH35946.1 - 7e-05 23.1 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) ERCC3_RAD25_C PF16203.5 PFH35946.1 - 0.0025 17.1 0.0 0.0066 15.7 0.0 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 PFH35946.1 - 0.004 16.4 0.0 0.021 14.0 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PseudoU_synth_2 PF00849.22 PFH35947.1 - 3.6e-19 69.4 0.0 2.3e-16 60.3 0.0 2.3 2 0 0 2 2 2 2 RNA pseudouridylate synthase S4 PF01479.25 PFH35947.1 - 1e-05 25.2 0.1 2e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 PFH35947.1 - 0.00066 19.5 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain YjbE PF11106.8 PFH35947.1 - 0.76 10.0 5.8 1.8 8.8 0.2 2.8 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Semialdhyde_dhC PF02774.18 PFH35948.1 - 3.3e-27 95.8 0.0 4.5e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 PFH35948.1 - 4.8e-26 91.6 0.0 8.1e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 PFH35948.1 - 0.011 15.8 0.0 0.029 14.5 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Acyl-CoA_dh_1 PF00441.24 PFH35949.1 - 4.6e-39 134.0 0.1 6.8e-39 133.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PFH35949.1 - 2.3e-32 112.0 0.0 5.3e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PFH35949.1 - 9.1e-22 77.1 0.1 1.6e-21 76.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PFH35949.1 - 8.8e-10 39.0 0.0 1.3e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 PFH35949.1 - 0.12 12.0 0.0 0.5 10.0 0.0 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Cpn60_TCP1 PF00118.24 PFH35950.1 - 4.3e-166 553.3 11.2 5e-166 553.2 11.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-AN1 PF01428.16 PFH35951.1 - 1.6e-17 63.4 26.6 2e-11 43.9 5.9 3.3 4 0 0 4 4 4 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 PFH35951.1 - 0.01 16.1 17.8 0.081 13.3 4.2 2.6 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain PhnA_Zn_Ribbon PF08274.12 PFH35951.1 - 0.12 12.3 0.3 0.12 12.3 0.3 2.7 2 1 0 2 2 2 0 PhnA Zinc-Ribbon GTP_EFTU PF00009.27 PFH35952.1 - 4.4e-67 225.4 0.1 7e-67 224.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 PFH35952.1 - 6.9e-30 103.3 0.0 2.8e-29 101.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 PFH35952.1 - 1.2e-22 79.7 0.0 2.5e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 PFH35952.1 - 2e-14 53.4 0.0 3.8e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 PFH35952.1 - 5.2e-12 46.0 0.0 2e-11 44.1 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PFH35952.1 - 0.00096 19.2 0.1 0.0021 18.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 PFH35952.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain ISP3_C PF18045.1 PFH35953.1 - 6.6e-12 45.3 0.0 8.7e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 ISP3 C-terminal ISP1_C PF18161.1 PFH35953.1 - 1.5e-10 41.0 0.0 2.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 ISP1 C-terminal DUF2118 PF09891.9 PFH35953.1 - 0.039 13.9 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) BT1 PF03092.16 PFH35954.1 - 2.1e-67 227.6 25.3 1.3e-40 139.2 14.1 2.1 1 1 0 2 2 2 2 BT1 family MFS_1 PF07690.16 PFH35954.1 - 1.9e-13 50.1 38.7 1.3e-09 37.5 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Utp14 PF04615.13 PFH35955.1 - 5.6e-101 339.4 89.6 5.6e-101 339.4 89.6 2.6 1 1 2 3 3 3 1 Utp14 protein Nop PF01798.18 PFH35956.1 - 7.1e-81 271.1 0.1 1.4e-80 270.0 0.1 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 PFH35956.1 - 7.2e-16 58.3 0.9 7.2e-16 58.3 0.9 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain MFS_1 PF07690.16 PFH35957.1 - 0.0001 21.4 40.3 0.0003 19.8 15.1 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.29 PFH35958.1 - 7e-27 94.3 0.0 4.3e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH35958.1 - 1.8e-18 66.9 0.0 4.9e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PFH35958.1 - 1.2e-13 51.1 0.1 2.3e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) NPR3 PF03666.13 PFH35958.1 - 0.0042 15.9 0.1 0.0042 15.9 0.1 3.8 2 1 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 ATP-synt_Eps PF04627.13 PFH35958.1 - 0.021 14.8 1.2 0.072 13.1 1.2 2.0 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain ResIII PF04851.15 PFH35958.1 - 0.028 14.4 0.0 5.9 6.8 0.0 3.4 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit UbiD PF01977.16 PFH35958.1 - 0.03 13.2 0.2 0.051 12.4 0.2 1.2 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase XRN_N PF03159.18 PFH35958.1 - 4.8 6.5 9.7 0.42 10.0 0.2 2.6 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus Pkinase PF00069.25 PFH35959.1 - 1.2e-40 139.5 0.0 7.3e-27 94.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH35959.1 - 5.5e-13 48.8 0.0 5.3e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PFH35959.1 - 9.6e-05 21.8 0.0 0.031 13.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 PFH35959.1 - 0.00038 19.4 0.1 0.00058 18.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase NAC PF01849.18 PFH35960.1 - 2.4e-20 72.3 0.2 5.7e-20 71.0 0.2 1.7 1 0 0 1 1 1 1 NAC domain Bac_surface_Ag PF01103.23 PFH35962.1 - 7.7e-09 35.5 0.0 0.0016 18.0 0.0 3.1 3 0 0 3 3 3 2 Surface antigen DUF3080 PF11279.8 PFH35962.1 - 0.083 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) DUF3437 PF11919.8 PFH35964.1 - 3.1 7.8 6.3 0.78 9.7 1.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) zf-C3HC4_2 PF13923.6 PFH35965.1 - 1.9e-11 43.6 7.4 3.7e-11 42.7 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PFH35965.1 - 5.4e-11 42.2 5.9 8.4e-11 41.6 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PFH35965.1 - 5.8e-10 38.9 5.4 9.3e-10 38.2 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH35965.1 - 2e-09 37.3 4.3 1.5e-08 34.5 4.8 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 PFH35965.1 - 8.6e-09 35.6 9.1 1.7e-08 34.7 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PFH35965.1 - 2.4e-08 33.8 6.2 3.9e-08 33.1 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PFH35965.1 - 8e-07 28.8 6.9 1.4e-06 28.1 6.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PFH35965.1 - 3.1e-06 27.2 6.0 5.3e-06 26.5 6.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PFH35965.1 - 9e-06 25.9 5.6 2.4e-05 24.5 5.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-P11 PF03854.14 PFH35965.1 - 0.02 14.6 4.5 0.032 13.9 4.5 1.2 1 0 0 1 1 1 0 P-11 zinc finger Rtf2 PF04641.12 PFH35965.1 - 0.023 14.1 0.0 0.023 14.1 0.0 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_4 PF14570.6 PFH35965.1 - 0.072 12.9 7.6 0.15 11.9 7.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain U-box PF04564.15 PFH35965.1 - 0.2 11.8 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 U-box domain zf-RING_6 PF14835.6 PFH35965.1 - 0.32 10.9 4.1 0.55 10.1 4.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 PFH35965.1 - 0.42 10.8 3.7 0.72 10.0 3.7 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_5 PF17121.5 PFH35965.1 - 0.49 10.3 2.0 0.87 9.5 2.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PFH35965.1 - 0.58 10.2 6.6 0.13 12.3 3.1 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 PFH35965.1 - 0.84 9.3 7.6 1.7 8.3 7.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 PFH35965.1 - 0.89 9.8 7.6 0.8 10.0 5.9 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 PFH35965.1 - 3.9 7.3 7.1 1.2 8.9 3.6 2.0 2 0 0 2 2 2 0 RING-like zinc finger OATP PF03137.20 PFH35967.1 - 2.1e-13 49.4 0.0 2.3e-05 22.9 0.0 3.1 3 0 0 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family ACDC PF14733.6 PFH35969.1 - 1.1e-15 57.6 0.1 2e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 PFH35969.1 - 3.1e-13 49.7 0.8 1.2e-05 25.4 0.2 2.4 2 0 0 2 2 2 2 AP2 domain GEMIN8 PF15348.6 PFH35969.1 - 0.069 13.4 1.1 0.17 12.2 1.1 1.6 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 F5_F8_type_C PF00754.25 PFH35970.1 - 1.3e-17 64.2 0.1 2.7e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 F5/8 type C domain Ricin_B_lectin PF00652.22 PFH35970.1 - 1.1e-05 25.7 0.2 0.0011 19.2 0.0 2.4 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Laminin_N PF00055.17 PFH35970.1 - 0.0087 15.7 0.0 0.0087 15.7 0.0 2.7 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) SF-assemblin PF06705.11 PFH35971.1 - 4.8e-39 134.2 21.8 5.8e-39 133.9 21.8 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Nup54_57_C PF18570.1 PFH35971.1 - 0.0045 16.5 3.1 0.013 15.1 3.1 1.8 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain DUF713 PF05218.14 PFH35971.1 - 0.0076 16.0 3.7 0.0076 16.0 3.7 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF713) nsp8 PF08717.10 PFH35971.1 - 0.027 14.4 1.4 0.031 14.1 0.5 1.5 2 0 0 2 2 2 0 nsp8 replicase Baculo_PEP_C PF04513.12 PFH35971.1 - 0.53 10.3 13.5 5.9 6.9 3.3 3.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Macoilin PF09726.9 PFH35971.1 - 0.79 8.2 21.2 1 7.8 11.0 2.0 1 1 1 2 2 2 0 Macoilin family Occludin_ELL PF07303.13 PFH35971.1 - 1.3 9.8 11.8 1.5 9.6 0.7 3.4 1 1 3 4 4 4 0 Occludin homology domain Wzy_C PF04932.15 PFH35972.1 - 0.7 9.5 7.2 0.15 11.7 2.9 1.9 2 0 0 2 2 2 0 O-Antigen ligase Pro_isomerase PF00160.21 PFH35974.1 - 8.6e-49 165.8 0.0 9.6e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 PFH35974.1 - 0.048 13.7 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain tRNA-synt_2 PF00152.20 PFH35975.1 - 3.5e-80 269.4 0.0 4.5e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PFH35975.1 - 1.2e-11 44.4 0.0 2.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PFH35975.1 - 3.3e-08 33.3 0.0 8e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) SGIII PF15467.6 PFH35975.1 - 0.22 10.7 3.8 0.34 10.1 3.8 1.1 1 0 0 1 1 1 0 Secretogranin-3 NARP1 PF12569.8 PFH35975.1 - 2.6 6.9 10.4 4.3 6.1 10.4 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 A_deaminase PF00962.22 PFH35976.1 - 2.9e-28 99.1 0.0 3.4e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase pPIWI_RE_Y PF18156.1 PFH35976.1 - 0.021 15.2 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 pPIWI_RE three-gene island domain Y EMC1_C PF07774.13 PFH35978.1 - 2.6e-51 174.3 0.0 3.7e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 PFH35978.1 - 9.5e-08 31.9 6.2 0.056 13.0 0.1 4.7 4 2 1 5 5 5 3 PQQ-like domain Sin3_corepress PF08295.12 PFH35979.1 - 7.3e-25 86.9 0.0 1.4e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 PFH35979.1 - 0.6 10.3 1.7 17 5.6 0.0 3.2 4 0 0 4 4 4 0 Paired amphipathic helix repeat Laminin_G_3 PF13385.6 PFH35980.1 - 6.8e-13 49.0 0.0 1.2e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 PFH35980.1 - 0.00033 21.2 0.0 0.00063 20.3 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 PFH35980.1 - 0.009 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain Methyltr_RsmB-F PF01189.17 PFH35981.1 - 5.3e-21 75.2 0.1 1.5e-12 47.6 0.0 4.2 4 0 0 4 4 4 4 16S rRNA methyltransferase RsmB/F UbiA PF01040.18 PFH35982.1 - 5.6e-43 147.1 15.5 5.6e-43 147.1 15.5 1.6 2 0 0 2 2 2 1 UbiA prenyltransferase family PHD PF00628.29 PFH35984.1 - 8.3e-07 28.8 6.5 8.3e-07 28.8 6.5 2.8 2 0 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.7 PFH35984.1 - 1.5e-05 25.2 2.2 1.5e-05 25.2 2.2 2.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 PFH35984.1 - 2.3e-05 24.6 2.0 2.3e-05 24.6 2.0 3.4 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 PFH35984.1 - 0.00011 22.0 0.7 0.00011 22.0 0.7 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PFH35984.1 - 0.00015 21.6 1.9 0.00015 21.6 1.9 2.6 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PFH35984.1 - 0.0046 17.0 0.3 0.0046 17.0 0.3 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 PFH35984.1 - 0.023 14.3 0.8 0.023 14.3 0.8 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H PF13771.6 PFH35984.1 - 0.025 14.8 5.8 0.16 12.3 0.3 2.6 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PFH35984.1 - 0.14 12.3 4.5 2.2 8.5 0.4 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-RING_11 PF17123.5 PFH35984.1 - 0.35 10.6 7.5 0.18 11.6 0.9 2.8 2 0 0 2 2 2 0 RING-like zinc finger zf-UDP PF14569.6 PFH35984.1 - 0.66 10.1 10.1 1 9.5 0.3 2.7 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING-like PF08746.11 PFH35984.1 - 4.5 7.7 14.5 3.6 8.0 3.0 3.0 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.6 PFH35984.1 - 9.9 6.2 20.8 0.023 14.6 3.1 4.2 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 ER_lumen_recept PF00810.18 PFH35985.1 - 5.3e-15 56.5 16.2 1.4e-13 51.9 10.9 2.5 2 1 0 2 2 2 1 ER lumen protein retaining receptor RF-1 PF00472.20 PFH35986.1 - 2.4e-20 72.6 9.0 3.6e-20 72.0 9.0 1.2 1 0 0 1 1 1 1 RF-1 domain Peptidase_S49_N PF08496.10 PFH35986.1 - 1.3 9.0 4.9 2 8.5 4.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Atg14 PF10186.9 PFH35987.1 - 1.1 8.3 5.1 11 5.0 0.0 2.7 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 PFH35987.1 - 3.3 8.4 4.7 28 5.4 0.2 3.3 3 0 0 3 3 3 0 SlyX Hus1 PF04005.12 PFH35988.1 - 1.1e-22 80.5 0.0 1.8e-22 79.8 0.0 1.4 1 1 0 1 1 1 1 Hus1-like protein DNA_photolyase PF00875.18 PFH35989.1 - 6.1e-15 55.6 0.0 1.2e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.14 PFH35989.1 - 0.018 14.6 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase Myosin_head PF00063.21 PFH35990.1 - 2.7e-124 415.9 0.0 6.1e-57 193.3 0.0 5.3 4 2 0 4 4 4 4 Myosin head (motor domain) IQ PF00612.27 PFH35990.1 - 1.3e-06 27.7 26.8 0.0032 17.1 2.5 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_16 PF13191.6 PFH35990.1 - 0.026 14.9 4.3 0.027 14.9 0.1 3.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 PFH35990.1 - 0.029 14.6 0.1 0.24 11.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain HNF-1_N PF04814.13 PFH35990.1 - 1.6 9.3 3.0 1.3 9.6 0.1 2.3 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus FH2 PF02181.23 PFH35991.1 - 3.4e-68 230.4 11.8 8.7e-67 225.8 0.2 2.2 2 0 0 2 2 2 2 Formin Homology 2 Domain TPR_10 PF13374.6 PFH35991.1 - 5.7e-14 51.5 0.0 0.0044 16.9 0.0 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 PFH35991.1 - 9.3e-10 38.7 8.1 0.0003 21.0 0.0 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PFH35991.1 - 0.00072 19.3 1.3 5.5 7.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PFH35991.1 - 0.0016 18.4 0.1 19 5.7 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Macoilin PF09726.9 PFH35991.1 - 0.025 13.1 5.9 0.073 11.6 4.4 2.6 2 0 0 2 2 2 0 Macoilin family TPR_8 PF13181.6 PFH35991.1 - 0.055 13.7 0.1 86 3.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Spc7 PF08317.11 PFH35991.1 - 0.065 12.1 21.9 0.0062 15.5 12.3 2.6 2 0 0 2 2 2 0 Spc7 kinetochore protein OEP PF02321.18 PFH35991.1 - 0.39 10.5 14.0 1.5 8.6 14.0 2.0 1 0 0 1 1 1 0 Outer membrane efflux protein TPR_7 PF13176.6 PFH35991.1 - 0.45 10.7 2.7 34 4.8 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Syntaxin-6_N PF09177.11 PFH35991.1 - 2.9 8.5 8.7 5.7 7.6 6.2 2.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF3584 PF12128.8 PFH35991.1 - 3.3 5.1 21.3 1.4 6.3 13.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Flagellin_C PF00700.21 PFH35991.1 - 4 7.9 13.3 0.47 10.8 3.3 2.6 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region Exonuc_VII_S PF02609.16 PFH35991.1 - 4 7.6 5.7 29 4.8 1.1 3.2 2 1 2 4 4 3 0 Exonuclease VII small subunit Prominin PF05478.11 PFH35991.1 - 4.3 5.2 6.3 10 3.9 6.3 1.5 1 0 0 1 1 1 0 Prominin SNARE PF05739.19 PFH35991.1 - 5.1 7.2 6.4 39 4.3 0.6 3.1 2 1 0 2 2 2 0 SNARE domain T3SS_needle_E PF08988.10 PFH35991.1 - 5.1 7.3 12.5 26 5.0 1.6 3.9 1 1 2 3 3 3 0 Type III secretion system, cytoplasmic E component of needle V-SNARE_C PF12352.8 PFH35991.1 - 9.2 6.6 11.7 31 4.9 3.3 3.5 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Cob_adeno_trans PF01923.18 PFH35991.1 - 9.9 6.3 7.5 15 5.7 0.3 2.6 2 0 0 2 2 2 0 Cobalamin adenosyltransferase CPW_WPC PF09717.10 PFH35992.1 - 5.9e-09 36.8 0.4 1e-08 36.0 0.4 1.3 1 0 0 1 1 1 1 Plasmodium falciparum domain of unknown function (CPW_WPC) Forkhead_N PF08430.12 PFH35992.1 - 0.32 11.6 0.8 0.58 10.8 0.8 1.6 1 1 0 1 1 1 0 Forkhead N-terminal region Peptidase_C54 PF03416.19 PFH35993.1 - 3.4e-38 131.7 0.0 5.6e-17 62.1 0.0 4.1 4 0 0 4 4 4 4 Peptidase family C54 Pyr_redox_2 PF07992.14 PFH35994.1 - 2.4e-69 233.8 0.5 3.5e-69 233.3 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PFH35994.1 - 5.9e-36 123.1 0.1 2.4e-35 121.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PFH35994.1 - 7.2e-23 80.9 3.8 5.4e-19 68.5 0.1 3.2 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PFH35994.1 - 8e-12 45.2 0.4 3.2e-11 43.3 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PFH35994.1 - 3.6e-07 29.6 3.8 3.6e-07 29.6 3.8 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 PFH35994.1 - 7.6e-07 28.5 5.9 1.7e-06 27.4 3.3 2.3 2 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 PFH35994.1 - 1.2e-06 28.7 4.6 0.0002 21.5 1.4 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PFH35994.1 - 6.6e-06 25.1 5.4 8.1e-05 21.5 0.2 3.3 3 1 1 4 4 4 1 HI0933-like protein Thi4 PF01946.17 PFH35994.1 - 1.2e-05 24.7 0.3 2.9e-05 23.4 0.3 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 PFH35994.1 - 6.8e-05 22.3 1.9 0.14 11.4 1.4 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PFH35994.1 - 0.00012 21.4 8.5 0.025 13.9 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 PFH35994.1 - 0.0004 19.7 6.0 0.007 15.6 1.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 PFH35994.1 - 0.0029 17.3 8.2 0.25 10.9 0.4 3.8 4 0 0 4 4 4 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 PFH35994.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 PFH35994.1 - 0.2 12.3 0.8 20 5.8 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.12 PFH35994.1 - 2 7.4 3.7 1.9 7.4 0.9 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein CBP_BcsR PF10945.8 PFH35995.1 - 0.013 15.0 0.1 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsR Peptidase_C14 PF00656.22 PFH35996.1 - 1.5e-49 169.2 0.0 2.7e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain CUE PF02845.16 PFH35996.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 CUE domain DUF1296 PF06972.11 PFH35996.1 - 0.2 11.8 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) UPF0020 PF01170.18 PFH35997.1 - 3.8e-05 23.4 0.0 9.6e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Peptidase_M16 PF00675.20 PFH35998.1 - 4.6e-22 78.6 0.0 1.4e-21 77.0 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 PFH35998.1 - 2.8e-12 46.5 0.0 1.1e-10 41.3 0.0 2.6 3 0 0 3 3 3 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 PFH35998.1 - 1.3e-07 31.8 0.1 0.0023 18.0 0.0 3.8 4 0 0 4 4 4 2 Peptidase M16 inactive domain AA_permease_C PF13906.6 PFH35999.1 - 0.051 13.6 0.4 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 C-terminus of AA_permease ASH PF15780.5 PFH36000.1 - 1.1e-83 275.7 36.3 2.1e-05 24.7 0.0 28.9 32 0 0 32 32 31 16 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 PFH36000.1 - 6e-29 100.2 9.3 0.0099 16.0 0.0 14.6 14 0 0 14 14 14 7 Flagellar-associated PapD-like Motile_Sperm PF00635.26 PFH36000.1 - 5.6e-23 80.9 0.7 0.00016 21.5 0.0 13.7 18 0 0 18 18 18 3 MSP (Major sperm protein) domain DUF1573 PF07610.11 PFH36000.1 - 2.6e-15 56.3 0.0 13 5.9 0.0 17.2 21 0 0 21 21 21 1 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 PFH36000.1 - 1.4e-08 34.9 6.8 6.7 7.0 0.0 11.6 13 0 0 13 13 12 1 Transmembrane protein 131-like MYCBPAP PF14646.6 PFH36000.1 - 7.8e-06 25.1 0.7 2.9 6.7 0.1 6.9 6 1 0 6 6 6 1 MYCBP-associated protein family N_BRCA1_IG PF16158.5 PFH36000.1 - 0.0003 21.5 0.3 5.4 7.8 0.0 5.6 5 1 1 6 6 5 1 Ig-like domain from next to BRCA1 gene AAA_33 PF13671.6 PFH36000.1 - 0.0016 18.6 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF756 PF05506.12 PFH36000.1 - 0.023 15.6 0.7 2.1 9.3 0.0 4.8 5 0 0 5 5 3 0 Domain of unknown function (DUF756) AAA_16 PF13191.6 PFH36000.1 - 0.054 13.9 0.6 0.17 12.2 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain BsuPI PF12690.7 PFH36000.1 - 0.13 12.3 0.1 80 3.4 0.0 4.8 3 0 0 3 3 3 0 Intracellular proteinase inhibitor EF-hand_7 PF13499.6 PFH36001.1 - 1.1e-19 70.6 1.1 1.5e-12 47.7 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PFH36001.1 - 2.7e-14 52.7 0.7 1e-09 38.1 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH36001.1 - 5.9e-09 35.2 0.3 6.2e-05 22.6 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 PFH36001.1 - 3.2e-08 32.6 0.2 0.0021 17.5 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 PFH36001.1 - 1.2e-05 24.5 0.0 0.0012 18.2 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 PFH36001.1 - 0.00011 22.4 0.0 0.43 10.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain DUF2267 PF10025.9 PFH36001.1 - 0.041 14.2 0.1 2.6 8.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) EF-hand_4 PF12763.7 PFH36001.1 - 0.49 10.4 2.7 7.8 6.5 0.1 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Kinesin PF00225.23 PFH36002.1 - 8.8e-83 278.0 0.0 4.7e-61 206.6 0.0 2.6 2 1 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 PFH36002.1 - 3.5e-20 72.5 0.0 6.4e-14 52.1 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding FH2 PF02181.23 PFH36003.1 - 3e-43 148.4 3.0 2.8e-35 122.1 0.3 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain HNF-1_N PF04814.13 PFH36003.1 - 0.0047 17.6 2.6 0.41 11.2 0.0 3.8 3 0 0 3 3 3 2 Hepatocyte nuclear factor 1 (HNF-1), N terminus Pkinase PF00069.25 PFH36004.1 - 1e-77 261.1 0.0 1.4e-77 260.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36004.1 - 1.1e-35 123.2 0.0 1.6e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 PFH36004.1 - 4.7e-29 97.8 5.1 2.2e-06 26.8 0.8 5.2 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 PFH36004.1 - 1.7e-23 82.9 2.3 9.9e-12 45.1 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH36004.1 - 2.5e-21 73.7 6.1 6.1e-06 25.8 0.0 4.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 PFH36004.1 - 1.4e-19 69.7 7.3 1.2e-05 25.0 1.0 4.8 3 1 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 PFH36004.1 - 3.3e-17 61.1 11.7 6.2e-06 25.5 0.1 5.0 5 0 0 5 5 5 4 EF hand EF-hand_4 PF12763.7 PFH36004.1 - 1.9e-05 24.5 1.8 0.045 13.7 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PFH36004.1 - 2.3e-05 24.7 0.0 0.21 11.9 0.0 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 PFH36004.1 - 3.9e-05 23.1 0.0 0.00024 20.5 0.0 2.1 1 1 0 2 2 2 1 Kinase-like EF-hand_9 PF14658.6 PFH36004.1 - 0.00017 21.8 0.1 0.044 14.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain Pkinase_fungal PF17667.1 PFH36004.1 - 0.0013 17.6 0.0 0.0024 16.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PFH36004.1 - 0.0026 17.2 0.3 0.0055 16.1 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH36004.1 - 0.0072 16.3 0.0 0.072 13.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Prenyltransf PF01255.19 PFH36004.1 - 0.047 13.2 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase DUF2267 PF10025.9 PFH36004.1 - 0.11 12.7 0.0 0.71 10.2 0.0 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Sigma70_r3 PF04539.16 PFH36005.1 - 3.8e-10 39.7 0.9 3.7e-09 36.6 0.1 3.1 2 0 0 2 2 2 1 Sigma-70 region 3 2-oxoacid_dh PF00198.23 PFH36007.1 - 2.6e-57 193.9 0.7 4.6e-57 193.2 0.1 1.7 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PFH36007.1 - 1.1e-50 169.4 12.7 2.3e-17 62.6 0.3 3.3 3 0 0 3 3 3 3 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 PFH36007.1 - 4.9e-14 51.9 1.8 0.00067 19.4 0.0 4.5 3 2 1 4 4 4 3 Biotin-lipoyl like PYNP_C PF07831.13 PFH36007.1 - 1.8e-06 27.5 0.6 1.2 8.9 0.1 3.8 3 0 0 3 3 3 3 Pyrimidine nucleoside phosphorylase C-terminal domain E3_binding PF02817.17 PFH36007.1 - 2.3e-05 24.6 1.5 4e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 e3 binding domain HlyD_3 PF13437.6 PFH36007.1 - 0.00023 21.8 5.6 4.6 8.0 0.1 5.5 4 2 1 5 5 5 1 HlyD family secretion protein DUF2118 PF09891.9 PFH36007.1 - 0.00036 20.5 1.2 3.9 7.4 0.0 3.9 3 1 1 4 4 4 2 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 PFH36007.1 - 0.00039 20.3 2.7 0.47 10.3 0.1 3.4 3 0 0 3 3 3 1 Glycine cleavage H-protein QRPTase_N PF02749.16 PFH36007.1 - 0.021 14.9 4.0 6.2 7.0 0.1 4.4 5 1 1 6 6 6 0 Quinolinate phosphoribosyl transferase, N-terminal domain NQRA PF05896.11 PFH36007.1 - 0.11 11.9 0.5 0.27 10.6 0.1 1.8 2 0 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) OHA PF14418.6 PFH36008.1 - 1e-15 57.3 0.0 2.2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 OST-HTH Associated domain CPBP PF02517.16 PFH36009.1 - 1.4e-05 25.4 0.1 1.4e-05 25.4 0.1 3.7 2 2 0 2 2 2 1 CPBP intramembrane metalloprotease UBX PF00789.20 PFH36010.1 - 0.12 12.5 0.1 0.52 10.6 0.0 2.1 2 0 0 2 2 2 0 UBX domain DUF4667 PF15700.5 PFH36010.1 - 0.29 11.2 13.5 0.68 10.0 13.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) zf-H2C2_2 PF13465.6 PFH36011.1 - 3.1e-20 71.6 13.4 5.1e-06 26.7 0.1 4.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 PFH36011.1 - 3e-16 58.7 29.5 0.00018 22.0 0.4 5.2 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 PFH36011.1 - 4.4e-15 55.2 27.6 8e-05 22.9 0.4 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-Di19 PF05605.12 PFH36011.1 - 6.2e-07 29.6 16.3 0.0002 21.6 4.8 2.8 1 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 PFH36011.1 - 0.00066 19.4 17.0 0.25 11.1 0.1 4.8 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-met PF12874.7 PFH36011.1 - 0.0037 17.6 0.5 0.0037 17.6 0.5 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type TRAF6_Z2 PF18048.1 PFH36011.1 - 0.0095 16.0 0.6 0.0095 16.0 0.6 5.4 5 0 0 5 5 5 1 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_3rep PF18868.1 PFH36011.1 - 0.016 15.9 9.1 0.022 15.4 0.5 3.7 3 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 PFH36011.1 - 0.035 14.2 8.2 1.3 9.2 1.5 3.0 2 0 0 2 2 2 0 Zinc ribbon domain Zn-C2H2_12 PF18112.1 PFH36011.1 - 0.039 14.4 10.4 1.5 9.3 0.1 4.1 4 0 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain Rad50_zn_hook PF04423.14 PFH36011.1 - 0.33 10.8 1.5 42 4.1 0.0 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-met2 PF12907.7 PFH36011.1 - 0.79 9.9 4.7 6.7 6.9 0.8 3.6 3 0 0 3 3 3 0 Zinc-binding zf-C2H2_6 PF13912.6 PFH36011.1 - 1.1 9.4 23.7 0.57 10.2 2.6 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 PFH36011.1 - 1.1 9.6 15.1 36 4.8 8.8 3.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_9 PF14369.6 PFH36011.1 - 2.6 8.4 5.5 44 4.4 0.1 3.8 3 0 0 3 3 3 0 zinc-ribbon zf-C2H2_9 PF16293.5 PFH36011.1 - 2.9 7.8 8.9 47 3.9 0.0 4.1 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 PFH36011.1 - 3.1 7.9 21.4 0.43 10.6 1.7 4.3 2 1 2 4 4 4 0 BED zinc finger zf-C2H2_jaz PF12171.8 PFH36011.1 - 5.7 7.4 26.5 0.69 10.3 1.4 4.4 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding zf-RING_7 PF02591.15 PFH36011.1 - 7.3 6.9 7.8 3 8.1 0.2 3.4 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf-C2H2_11 PF16622.5 PFH36011.1 - 8.1 6.3 23.3 0.16 11.8 0.5 4.3 5 0 0 5 5 3 0 zinc-finger C2H2-type RRM_1 PF00076.22 PFH36012.1 - 2.6e-10 40.0 0.0 1.6e-05 24.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 PFH36012.1 - 0.068 13.2 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 Smg-4/UPF3 family SPOC PF07744.13 PFH36013.1 - 4.5e-07 29.9 0.0 7.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 SPOC domain Med22 PF06179.12 PFH36014.1 - 0.0042 17.3 0.1 0.0042 17.3 0.1 1.5 2 0 0 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF3273 PF11677.8 PFH36015.1 - 1.8e-72 243.9 9.4 2.4e-72 243.5 9.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Extensin-like_C PF06904.12 PFH36016.1 - 0.013 15.6 3.2 0.013 15.6 1.9 1.6 1 1 1 2 2 2 0 Extensin-like protein C-terminus Fringe PF02434.16 PFH36016.1 - 0.092 12.2 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Fringe-like UQ_con PF00179.26 PFH36018.1 - 6.2e-47 158.8 0.0 7.1e-47 158.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PFH36018.1 - 0.0023 17.8 0.0 0.0044 16.9 0.0 1.5 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 PFH36018.1 - 0.016 14.9 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 PFH36018.1 - 0.12 12.7 0.3 0.13 12.5 0.3 1.5 1 1 0 1 1 1 0 RWD domain RRM_1 PF00076.22 PFH36019.1 - 4e-16 58.6 0.1 6.7e-07 29.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 PFH36019.1 - 0.0045 17.0 0.2 0.41 10.7 0.0 3.1 3 0 0 3 3 3 1 Limkain b1 RRM_7 PF16367.5 PFH36019.1 - 0.04 14.0 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif zf-C3HC4_3 PF13920.6 PFH36020.1 - 8.5e-12 44.7 8.7 1.4e-11 44.1 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PFH36020.1 - 0.00018 21.7 11.8 0.00032 21.0 11.8 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 PFH36020.1 - 0.016 15.1 10.1 0.032 14.1 10.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PFH36020.1 - 0.024 14.5 11.5 0.043 13.7 11.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH36020.1 - 0.083 12.9 13.7 0.15 12.0 13.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.14 PFH36020.1 - 0.65 9.7 6.2 1.3 8.7 6.2 1.4 1 0 0 1 1 1 0 P-11 zinc finger Pkinase PF00069.25 PFH36021.1 - 7.4e-23 81.2 0.0 5.2e-19 68.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36021.1 - 4.3e-08 32.7 0.0 1.7e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4345 PF14248.6 PFH36021.1 - 0.012 15.5 0.4 0.031 14.2 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) Mob1_phocein PF03637.17 PFH36022.1 - 5.6e-32 111.1 0.1 1.1e-31 110.2 0.1 1.4 1 1 0 1 1 1 1 Mob1/phocein family DUF3883 PF13020.6 PFH36023.1 - 5.6e-20 71.2 0.0 9.9e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) eRF1_2 PF03464.15 PFH36024.1 - 6.7e-45 152.7 0.0 1.1e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 PFH36024.1 - 4.9e-37 126.9 0.2 1.1e-36 125.7 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 PFH36024.1 - 2.3e-19 69.7 0.0 3.9e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 PFH36024.1 - 1.6e-09 38.1 0.0 2.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 PFH36024.1 - 4.9e-09 36.6 0.0 8.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Ribosomal_L7Ae PF01248.26 PFH36024.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family T3SS_ExsE PF18286.1 PFH36025.1 - 0.0074 16.2 0.2 0.049 13.6 0.1 2.5 2 0 0 2 2 2 1 Type III secretion system ExsE Asp_protease PF09668.10 PFH36026.1 - 2.6e-53 179.1 0.0 4.1e-53 178.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 PFH36026.1 - 7.7e-19 68.1 0.0 2.6e-18 66.3 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease UBA PF00627.31 PFH36026.1 - 1.5e-10 40.7 0.4 4.3e-10 39.3 0.4 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Asp_protease_2 PF13650.6 PFH36026.1 - 3.6e-10 40.3 0.0 1.2e-09 38.7 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 PFH36026.1 - 5.2e-07 29.3 0.1 1.3e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family RVP_2 PF08284.11 PFH36026.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 PFH36026.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Rad60-SLD PF11976.8 PFH36026.1 - 0.063 13.1 0.0 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like HTH_WhiA PF02650.14 PFH36026.1 - 0.093 13.1 0.7 0.21 12.0 0.7 1.5 1 0 0 1 1 1 0 WhiA C-terminal HTH domain LRR_4 PF12799.7 PFH36027.1 - 1.9e-10 40.8 5.4 0.01 16.2 0.1 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH36027.1 - 9.4e-07 28.5 3.5 0.00024 20.8 0.1 3.6 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 PFH36027.1 - 9.7e-06 25.2 0.4 0.14 12.3 0.1 4.1 4 0 0 4 4 4 1 Leucine Rich repeat LRR_9 PF14580.6 PFH36027.1 - 0.019 14.5 0.2 0.032 13.8 0.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 PFH36027.1 - 0.68 10.7 9.8 9.2 7.3 0.1 4.5 5 1 0 5 5 5 0 Leucine Rich Repeat GST_N_3 PF13417.6 PFH36028.1 - 3.2e-09 37.1 0.1 5.4e-08 33.1 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 PFH36028.1 - 4e-07 30.1 0.6 8.8e-07 29.1 0.6 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 PFH36028.1 - 0.00026 21.2 0.0 0.00079 19.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PFH36028.1 - 0.017 15.2 0.1 0.061 13.4 0.1 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 PFH36028.1 - 0.035 13.9 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain His_Phos_2 PF00328.22 PFH36029.1 - 6.8e-47 160.6 0.0 1.9e-43 149.3 0.0 3.7 3 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 PFH36029.1 - 1.7e-34 117.8 0.0 3e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 PFH36029.1 - 0.00043 19.9 0.0 0.00083 19.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain OmpH PF03938.14 PFH36030.1 - 2.4 8.5 4.7 8.6 6.7 4.7 1.9 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ABC_tran_Xtn PF12848.7 PFH36030.1 - 5.3 7.1 12.0 0.026 14.5 2.0 2.4 2 0 0 2 2 2 0 ABC transporter ATG_C PF09333.11 PFH36031.1 - 5.4e-06 26.7 0.0 2.6e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 PFH36031.1 - 0.00057 20.0 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Herpes_LMP2 PF07415.11 PFH36033.1 - 0.00047 19.1 3.0 0.00068 18.5 3.0 1.2 1 0 0 1 1 1 1 Gammaherpesvirus latent membrane protein (LMP2) protein OST3_OST6 PF04756.13 PFH36033.1 - 0.025 13.9 0.3 0.035 13.4 0.3 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Phage_holin_3_6 PF07332.11 PFH36033.1 - 0.04 14.0 6.4 0.076 13.1 6.4 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM192 PF14802.6 PFH36033.1 - 0.056 12.5 1.3 0.071 12.2 1.3 1.2 1 0 0 1 1 1 0 TMEM192 family DUF2207 PF09972.9 PFH36033.1 - 0.12 11.2 2.0 0.15 10.8 2.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Trp_oprn_chp PF09534.10 PFH36033.1 - 0.42 10.4 5.6 0.084 12.7 2.4 1.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4191 PF13829.6 PFH36033.1 - 0.89 8.9 6.0 1.7 7.9 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Exosortase_EpsH PF09721.10 PFH36034.1 - 0.0069 16.0 3.7 0.0088 15.6 3.7 1.1 1 0 0 1 1 1 1 Transmembrane exosortase (Exosortase_EpsH) SCAMP PF04144.13 PFH36034.1 - 0.02 15.2 1.7 0.028 14.8 1.7 1.2 1 0 0 1 1 1 0 SCAMP family FA_desaturase PF00487.24 PFH36034.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF2207 PF09972.9 PFH36034.1 - 0.031 13.1 1.9 0.038 12.8 1.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 PFH36034.1 - 0.031 14.3 9.0 0.057 13.5 9.0 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4282 PF14110.6 PFH36034.1 - 0.041 14.6 6.9 0.074 13.8 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF2663 PF10864.8 PFH36034.1 - 0.046 14.1 0.7 0.082 13.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF2271 PF10029.9 PFH36034.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) Peptidase_S9 PF00326.21 PFH36034.1 - 0.17 11.3 0.0 0.44 10.0 0.0 1.6 1 1 1 2 2 2 0 Prolyl oligopeptidase family DUF3043 PF11241.8 PFH36034.1 - 1.1 9.3 3.9 1.7 8.6 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) adh_short PF00106.25 PFH36035.1 - 9.7e-33 113.3 4.5 7.6e-20 71.2 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PFH36035.1 - 3.1e-13 49.8 6.3 1e-09 38.3 0.1 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PFH36035.1 - 3.5e-07 30.3 6.7 5.6e-07 29.6 3.0 2.2 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 PFH36035.1 - 0.00039 19.7 0.2 0.00062 19.0 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 PFH36035.1 - 0.0029 17.1 0.0 0.0053 16.2 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PFH36035.1 - 0.025 14.1 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 PFH36035.1 - 0.088 12.6 0.1 0.27 11.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 PFH36035.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain zf-RING_2 PF13639.6 PFH36036.1 - 2.1e-09 37.6 7.3 5.1e-09 36.3 7.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PFH36036.1 - 3.4e-08 33.2 6.9 6.9e-08 32.2 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PFH36036.1 - 4.4e-07 30.1 9.7 2.3e-06 27.8 9.7 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PFH36036.1 - 2.9e-06 27.1 5.8 5.4e-06 26.2 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PFH36036.1 - 0.00016 21.5 3.3 0.00016 21.5 3.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH36036.1 - 0.0002 21.3 4.7 0.00041 20.3 4.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PFH36036.1 - 0.00067 19.6 5.7 0.0034 17.3 6.0 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 PFH36036.1 - 0.0011 18.6 2.3 0.0011 18.6 2.3 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 PFH36036.1 - 0.0014 18.5 5.0 0.0032 17.3 5.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PFH36036.1 - 0.003 17.6 3.8 0.011 15.7 3.8 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 PFH36036.1 - 0.0039 16.9 4.6 0.0098 15.6 4.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING-like PF08746.11 PFH36036.1 - 0.019 15.3 4.2 0.019 15.3 4.2 1.9 2 0 0 2 2 1 0 RING-like domain FANCL_C PF11793.8 PFH36036.1 - 0.31 11.2 3.0 0.82 9.9 2.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain CCDC53 PF10152.9 PFH36036.1 - 3.8 7.9 4.8 61 4.0 0.0 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex NYD-SP28_assoc PF14775.6 PFH36038.1 - 0.017 15.2 4.6 0.034 14.2 4.6 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain KH_1 PF00013.29 PFH36038.1 - 0.049 13.5 0.0 3 7.7 0.0 2.6 2 0 0 2 2 2 0 KH domain GIT_CC PF16559.5 PFH36038.1 - 1.3 9.0 7.8 3.5 7.6 7.8 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor PARG_cat PF05028.14 PFH36039.1 - 1.5e-80 271.0 0.0 2.1e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Flagellar_rod PF05149.12 PFH36040.1 - 0.01 15.3 0.7 0.022 14.2 0.7 1.5 1 0 0 1 1 1 0 Paraflagellar rod protein Dpy19 PF10034.9 PFH36041.1 - 2.3e-125 419.3 2.8 1.6e-76 258.0 0.0 2.0 2 0 0 2 2 2 2 Q-cell neuroblast polarisation MRC1 PF09444.10 PFH36041.1 - 0.0019 18.7 2.9 0.0019 18.7 2.9 2.0 3 0 0 3 3 3 1 MRC1-like domain PDEase_I PF00233.19 PFH36042.1 - 2e-77 260.1 1.3 3.1e-77 259.5 1.3 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 PFH36042.1 - 0.019 15.2 0.1 0.051 13.8 0.1 1.7 1 0 0 1 1 1 0 HD domain TIP120 PF08623.10 PFH36043.1 - 0.00033 20.5 0.0 1.4 8.7 0.0 2.7 2 0 0 2 2 2 2 TATA-binding protein interacting (TIP20) DALR_1 PF05746.15 PFH36043.1 - 0.037 14.2 0.0 0.31 11.2 0.0 2.4 2 0 0 2 2 2 0 DALR anticodon binding domain HEAT PF02985.22 PFH36043.1 - 0.047 14.0 2.7 41 4.8 0.3 5.0 5 0 0 5 5 5 0 HEAT repeat CLASP_N PF12348.8 PFH36043.1 - 0.51 9.9 2.4 21 4.6 0.1 3.0 2 1 1 3 3 3 0 CLASP N terminal E1_DerP2_DerF2 PF02221.15 PFH36044.1 - 4.8e-05 23.8 0.0 8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 ML domain GAS PF13851.6 PFH36045.1 - 1e-05 25.0 49.7 0.007 15.7 18.7 3.4 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding BTK PF00779.19 PFH36045.1 - 0.0011 18.8 4.3 0.0027 17.5 4.3 1.6 1 0 0 1 1 1 1 BTK motif FUSC PF04632.12 PFH36045.1 - 0.0014 17.2 17.3 0.0014 17.2 17.3 1.9 1 1 1 2 2 2 1 Fusaric acid resistance protein family DUF2353 PF09789.9 PFH36045.1 - 0.0028 17.1 20.6 0.0028 17.1 20.6 2.6 2 1 0 3 3 3 1 Uncharacterized coiled-coil protein (DUF2353) Fez1 PF06818.15 PFH36045.1 - 0.0039 17.7 16.5 0.0039 17.7 16.5 2.7 1 1 2 3 3 3 1 Fez1 MscS_porin PF12795.7 PFH36045.1 - 0.0059 16.2 26.7 0.0059 16.2 26.7 2.6 1 1 1 2 2 1 1 Mechanosensitive ion channel porin domain Golgin_A5 PF09787.9 PFH36045.1 - 0.0075 15.8 15.3 0.0075 15.8 15.3 2.4 1 1 1 2 2 2 1 Golgin subfamily A member 5 DUF5082 PF16888.5 PFH36045.1 - 0.032 14.5 1.3 0.032 14.5 1.3 4.6 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) ATG16 PF08614.11 PFH36045.1 - 0.057 13.6 56.6 0.18 12.0 10.6 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) SYCE1 PF15233.6 PFH36045.1 - 0.087 12.9 43.5 0.043 13.9 16.9 3.2 2 1 1 3 3 3 0 Synaptonemal complex central element protein 1 TPR_MLP1_2 PF07926.12 PFH36045.1 - 0.14 12.2 51.3 0.24 11.5 8.8 3.9 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 PFH36045.1 - 0.2 10.5 45.8 0.19 10.6 19.4 2.6 1 1 0 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 PFH36045.1 - 0.32 11.5 62.0 0.27 11.8 11.9 4.5 2 1 1 3 3 3 0 Apg6 coiled-coil region Leu_zip PF15294.6 PFH36045.1 - 1.4 8.4 40.4 1.2 8.5 13.0 2.9 1 1 2 3 3 3 0 Leucine zipper UQ_con PF00179.26 PFH36047.1 - 1.7e-41 141.1 0.0 2e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 PFH36047.1 - 0.024 14.3 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 PFH36047.1 - 0.089 13.1 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain AP2 PF00847.20 PFH36049.1 - 6.5e-12 45.5 0.5 1.1e-11 44.7 0.5 1.4 1 0 0 1 1 1 1 AP2 domain ACDC PF14733.6 PFH36050.1 - 2.2e-15 56.7 0.0 3.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 PFH36050.1 - 1.3e-14 54.2 0.3 3.3e-14 52.8 0.3 1.7 1 0 0 1 1 1 1 AP2 domain Complex1_LYR_2 PF13233.6 PFH36051.1 - 3.9e-08 33.9 4.5 6.7e-07 30.0 4.5 2.7 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 PFH36051.1 - 1e-05 25.4 1.2 3.1e-05 23.9 0.6 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) EF-hand_6 PF13405.6 PFH36052.1 - 1.4e-08 34.0 1.1 0.00046 19.9 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PFH36052.1 - 3.1e-08 34.0 1.7 5.6e-08 33.1 1.7 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PFH36052.1 - 1.2e-07 30.7 1.9 0.00025 20.4 0.0 2.7 2 0 0 2 2 2 2 EF hand COPI_assoc PF08507.10 PFH36052.1 - 8.6e-06 25.8 8.0 1.3e-05 25.3 8.0 1.2 1 0 0 1 1 1 1 COPI associated protein EF-hand_5 PF13202.6 PFH36052.1 - 1.3e-05 24.5 1.0 0.00015 21.1 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 PFH36052.1 - 3.9e-05 23.4 0.4 7.9e-05 22.4 0.4 1.6 1 0 0 1 1 1 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PFH36052.1 - 0.071 13.4 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Phage_holin_3_6 PF07332.11 PFH36052.1 - 0.74 9.9 3.3 2 8.5 0.3 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III FxsA PF04186.13 PFH36052.1 - 0.77 9.9 5.0 0.89 9.7 1.7 2.6 2 1 0 2 2 2 0 FxsA cytoplasmic membrane protein DUF872 PF05915.12 PFH36052.1 - 3.3 7.9 7.6 2.4 8.3 0.8 2.9 1 1 2 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Ufd2P_core PF10408.9 PFH36053.1 - 2.1e-149 499.0 0.0 2.5e-149 498.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 PFH36053.1 - 1.8e-22 79.3 1.3 3.6e-22 78.3 1.3 1.5 1 0 0 1 1 1 1 U-box domain Ribosomal_60s PF00428.19 PFH36053.1 - 0.0021 18.6 3.5 0.0021 18.6 3.5 2.5 2 0 0 2 2 2 1 60s Acidic ribosomal protein TipAS PF07739.13 PFH36053.1 - 0.023 15.3 0.1 0.14 12.7 0.0 2.4 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Sulfate_transp PF00916.20 PFH36054.1 - 3.4e-24 85.3 19.0 1.2e-23 83.5 14.0 2.4 2 1 0 2 2 2 1 Sulfate permease family STAS PF01740.21 PFH36054.1 - 0.00066 19.3 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 PFH36054.1 - 0.0097 16.3 3.3 0.0097 16.3 3.3 3.5 3 1 0 3 3 3 2 Molybdate transporter of MFS superfamily Dpy-30 PF05186.13 PFH36055.1 - 2.5e-14 52.7 0.4 3.4e-14 52.2 0.4 1.2 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 PFH36055.1 - 0.17 11.6 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DTW PF03942.15 PFH36058.1 - 1.2e-15 57.8 7.1 9.1e-14 51.6 5.6 2.7 2 1 0 2 2 2 2 DTW domain Ecm29 PF13001.7 PFH36059.1 - 2.3e-19 69.4 0.0 2.5e-17 62.8 0.0 3.1 3 1 0 3 3 3 1 Proteasome stabiliser HEAT_2 PF13646.6 PFH36059.1 - 0.00091 19.6 2.3 0.00091 19.6 2.3 6.9 8 0 0 8 8 8 1 HEAT repeats HEAT PF02985.22 PFH36059.1 - 0.038 14.2 0.1 0.038 14.2 0.1 6.1 5 0 0 5 5 5 0 HEAT repeat DUF4778 PF16008.5 PFH36059.1 - 0.17 11.9 2.4 2.3 8.2 1.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4778) HEAT_EZ PF13513.6 PFH36059.1 - 3 8.4 18.2 0.05 14.1 2.0 6.5 5 1 1 6 6 6 0 HEAT-like repeat Clat_adaptor_s PF01217.20 PFH36060.1 - 1.3e-08 34.9 0.7 2.9e-08 33.7 0.7 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Pyr_redox_2 PF07992.14 PFH36061.1 - 1.3e-16 60.7 1.4 9e-16 58.0 1.4 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIRS_C PF02769.22 PFH36061.1 - 5.8e-16 59.0 3.7 1.6e-15 57.6 0.3 2.9 2 1 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 PFH36061.1 - 3e-11 43.8 1.9 8.7e-11 42.3 0.1 2.4 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Pyr_redox PF00070.27 PFH36061.1 - 0.00058 20.4 0.7 0.34 11.5 0.7 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF4110 PF13422.6 PFH36062.1 - 0.69 10.0 3.0 1.9 8.6 3.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) tRNA-synt_His PF13393.6 PFH36063.1 - 7.5e-45 153.5 0.0 7.5e-45 153.5 0.0 2.3 3 0 0 3 3 3 1 Histidyl-tRNA synthetase Lyase_aromatic PF00221.19 PFH36063.1 - 6.7e-11 41.5 1.9 7.1e-05 21.6 0.0 2.2 2 0 0 2 2 2 2 Aromatic amino acid lyase HGTP_anticodon PF03129.20 PFH36063.1 - 2.3e-10 40.5 0.0 5.9e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 PFH36063.1 - 0.00085 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 PFH36063.1 - 0.024 13.7 0.2 0.074 12.1 0.0 1.8 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 PFH36063.1 - 0.089 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) MCU PF04678.13 PFH36065.1 - 1e-21 77.8 0.0 1.8e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter SRP54 PF00448.22 PFH36066.1 - 4.6e-54 183.0 0.5 1.3e-53 181.6 0.5 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 PFH36066.1 - 4e-25 89.3 7.3 2.8e-23 83.3 0.1 2.1 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal MeaB PF03308.16 PFH36066.1 - 4.1e-05 22.7 0.1 7.5e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 PFH36066.1 - 0.00036 20.3 0.3 0.00066 19.5 0.3 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 PFH36066.1 - 0.002 18.1 0.0 2.9 7.8 0.0 2.5 2 0 0 2 2 2 2 NTPase AAA_16 PF13191.6 PFH36066.1 - 0.005 17.2 0.1 0.018 15.4 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain SRP54_N PF02881.19 PFH36066.1 - 0.0052 17.0 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 PFH36066.1 - 0.037 14.1 0.1 0.62 10.1 0.2 2.5 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DAP3 PF10236.9 PFH36066.1 - 0.12 11.5 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 CLP1_P PF16575.5 PFH36066.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 PFH36066.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 PFH36066.1 - 0.24 11.5 2.3 2.3 8.4 1.2 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase HECT PF00632.25 PFH36068.1 - 5.5e-38 131.2 0.0 9.2e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Sugar_transport PF06800.12 PFH36069.1 - 4.2e-09 36.2 11.4 1.4e-06 27.8 1.9 2.3 2 0 0 2 2 2 2 Sugar transport protein UDPGT PF00201.18 PFH36069.1 - 0.095 11.5 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase DNA_pol_E_B PF04042.16 PFH36070.1 - 5.8e-27 94.4 0.0 9.7e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B OKR_DC_1 PF01276.20 PFH36071.1 - 2.8e-73 247.0 0.0 1.8e-52 178.5 0.0 2.2 2 0 0 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 PFH36071.1 - 0.0018 18.6 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain Beta_elim_lyase PF01212.21 PFH36071.1 - 0.0021 17.4 0.0 0.0045 16.3 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 PFH36071.1 - 0.017 14.3 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II HopW1-1 PF15457.6 PFH36071.1 - 0.095 11.9 0.1 0.33 10.2 0.1 1.8 2 0 0 2 2 2 0 Type III T3SS secreted effector HopW1-1/HopPmaA Proteasome PF00227.26 PFH36072.1 - 2.6e-26 92.3 0.0 4.6e-12 45.8 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit CPBP PF02517.16 PFH36073.1 - 8e-17 61.4 0.0 6.2e-16 58.5 0.0 2.4 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease SAG PF04092.13 PFH36074.1 - 8.6e-41 139.8 20.9 5.5e-23 82.2 1.6 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36075.1 - 9.7e-45 152.6 20.5 5.2e-23 82.3 1.1 2.3 2 0 0 2 2 2 2 SRS domain 7tm_1 PF00001.21 PFH36075.1 - 0.0048 16.2 0.1 0.0082 15.5 0.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SAG PF04092.13 PFH36076.1 - 1.4e-46 158.5 20.1 4e-24 85.9 2.5 2.1 2 0 0 2 2 2 2 SRS domain DUF3175 PF11373.8 PFH36076.1 - 0.17 12.0 0.9 8.6 6.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3175) UPAR_LY6_2 PF16975.5 PFH36076.1 - 0.25 11.6 0.0 0.25 11.6 0.0 2.7 3 1 0 3 3 3 0 Ly6/PLAUR domain-containing protein 6, Lypd6 SAG PF04092.13 PFH36077.1 - 2.8e-46 157.5 19.2 1.9e-23 83.7 1.7 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36078.1 - 8.5e-41 139.8 9.1 1.3e-22 81.0 0.1 2.2 2 0 0 2 2 2 2 SRS domain Lustrin_cystein PF14625.6 PFH36078.1 - 0.37 11.2 0.1 0.37 11.2 0.1 2.9 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain Kinocilin PF15033.6 PFH36078.1 - 2.4 7.8 7.4 0.097 12.3 0.8 2.0 2 0 0 2 2 2 0 Kinocilin protein SAG PF04092.13 PFH36079.1 - 5.1e-41 140.5 21.6 2.4e-23 83.4 4.9 2.1 2 0 0 2 2 2 2 SRS domain GPHR_N PF12537.8 PFH36079.1 - 0.13 12.3 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal PHZA_PHZB PF03284.13 PFH36079.1 - 0.18 11.4 0.1 1.3 8.7 0.0 2.3 2 1 0 2 2 2 0 Phenazine biosynthesis protein A/B SAG PF04092.13 PFH36080.1 - 5.7e-47 159.8 26.9 1.1e-23 84.5 6.9 2.1 2 0 0 2 2 2 2 SRS domain DUF2597 PF10772.9 PFH36080.1 - 0.17 11.9 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) Transglut_N PF00868.20 PFH36080.1 - 0.71 10.2 2.8 24 5.3 0.2 2.9 4 0 0 4 4 4 0 Transglutaminase family SAG PF04092.13 PFH36081.1 - 7.9e-39 133.5 22.4 3.4e-19 69.9 1.2 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36082.1 - 4.7e-41 140.7 21.1 2.1e-21 77.1 3.6 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36083.1 - 6.2e-45 153.2 28.7 1.1e-23 84.4 6.7 2.4 2 1 1 3 3 3 2 SRS domain Transglut_N PF00868.20 PFH36083.1 - 0.06 13.7 2.7 3.4 8.0 0.2 3.0 3 0 0 3 3 3 0 Transglutaminase family ALS2CR11 PF15729.5 PFH36083.1 - 0.12 11.5 0.2 0.18 10.9 0.2 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 SAG PF04092.13 PFH36084.1 - 2.3e-41 141.7 23.1 3.6e-21 76.3 0.9 2.1 2 0 0 2 2 2 2 SRS domain CD45 PF12567.8 PFH36084.1 - 0.076 13.0 1.4 0.23 11.4 1.4 1.9 1 0 0 1 1 1 0 Leukocyte receptor CD45 SAG PF04092.13 PFH36085.1 - 9.4e-42 142.9 18.1 6.7e-22 78.7 2.4 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36086.1 - 1.9e-84 281.1 40.4 8.4e-25 88.1 1.9 4.1 4 0 0 4 4 4 4 SRS domain Ground-like PF04155.18 PFH36086.1 - 0.0031 18.1 2.7 3 8.6 0.1 3.1 3 0 0 3 3 3 2 Ground-like domain CVNH PF08881.10 PFH36086.1 - 0.03 15.0 0.1 0.13 12.9 0.1 2.1 1 0 0 1 1 1 0 CVNH domain NigD_N PF12667.7 PFH36086.1 - 0.067 13.3 0.0 23 5.2 0.0 2.7 2 0 0 2 2 2 0 NigD-like N-terminal OB domain SAG PF04092.13 PFH36087.1 - 1.6e-44 151.9 23.7 1.8e-24 87.0 2.1 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36088.1 - 1.2e-41 142.6 11.8 1.2e-21 77.8 1.4 2.1 2 0 0 2 2 2 2 SRS domain Pilin PF00114.19 PFH36088.1 - 0.04 14.9 2.0 0.04 14.9 2.0 2.8 2 1 1 3 3 3 0 Pilin (bacterial filament) SAG PF04092.13 PFH36089.1 - 1.9e-40 138.7 24.9 5.7e-23 82.1 6.2 2.1 2 0 0 2 2 2 2 SRS domain PHZA_PHZB PF03284.13 PFH36089.1 - 0.036 13.7 0.1 0.09 12.4 0.0 1.7 2 0 0 2 2 2 0 Phenazine biosynthesis protein A/B Ground-like PF04155.18 PFH36089.1 - 0.81 10.4 6.2 0.7 10.6 0.5 3.4 4 0 0 4 4 4 0 Ground-like domain SAG PF04092.13 PFH36090.1 - 1.8e-104 345.8 54.1 4.9e-23 82.4 1.8 5.2 4 1 1 5 5 5 5 SRS domain PHZA_PHZB PF03284.13 PFH36090.1 - 0.0024 17.5 0.2 2.4 7.8 0.1 2.6 2 0 0 2 2 2 2 Phenazine biosynthesis protein A/B Eryth_link_C PF16915.5 PFH36090.1 - 0.039 14.0 0.6 25 4.9 0.0 3.7 3 0 0 3 3 3 0 Annelid erythrocruorin linker subunit C-terminus Ground-like PF04155.18 PFH36090.1 - 0.045 14.4 3.3 15 6.3 0.1 4.1 3 0 0 3 3 3 0 Ground-like domain SAG PF04092.13 PFH36091.1 - 5.5e-40 137.2 19.7 1e-22 81.3 3.5 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36092.1 - 1.7e-42 145.3 21.8 5.8e-23 82.1 6.2 2.2 2 0 0 2 2 2 2 SRS domain PHZA_PHZB PF03284.13 PFH36092.1 - 0.049 13.3 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B Eryth_link_C PF16915.5 PFH36092.1 - 0.06 13.4 0.1 6.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Annelid erythrocruorin linker subunit C-terminus SAG PF04092.13 PFH36093.1 - 6.3e-43 146.7 26.2 1.6e-23 83.9 7.0 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36094.1 - 6e-42 143.6 21.5 1.4e-23 84.1 6.6 2.1 2 0 0 2 2 2 2 SRS domain Mersacidin PF16934.5 PFH36094.1 - 0.027 14.3 1.4 1.3 8.8 0.4 2.7 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) Ground-like PF04155.18 PFH36094.1 - 0.16 12.6 0.1 0.16 12.6 0.1 2.2 2 0 0 2 2 2 0 Ground-like domain Haemadin PF09065.10 PFH36094.1 - 3.1 7.7 6.6 6.8 6.6 0.4 3.7 3 0 0 3 3 3 0 Haemadin SAG PF04092.13 PFH36095.1 - 3e-41 141.3 21.7 2.6e-22 80.0 6.7 2.2 2 0 0 2 2 2 2 SRS domain Transglut_N PF00868.20 PFH36095.1 - 0.15 12.4 0.4 0.83 10.0 0.3 2.1 2 0 0 2 2 2 0 Transglutaminase family DUF2415 PF10313.9 PFH36095.1 - 0.19 11.7 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) SAG PF04092.13 PFH36096.1 - 7.9e-39 133.5 24.0 6.8e-21 75.4 4.4 2.2 2 0 0 2 2 2 2 SRS domain PHZA_PHZB PF03284.13 PFH36096.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B SAG PF04092.13 PFH36097.1 - 3.2e-45 154.2 23.8 5.3e-23 82.2 4.5 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36098.1 - 3.1e-43 147.7 25.3 5.2e-24 85.5 3.8 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36099.1 - 2.4e-43 148.1 24.5 4.2e-24 85.8 3.1 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36100.1 - 3.2e-43 147.7 22.2 4e-23 82.6 4.7 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36101.1 - 4.9e-43 147.1 14.9 5.1e-24 85.5 0.4 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36102.1 - 2.9e-43 147.8 21.0 2.6e-24 86.5 4.6 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36103.1 - 2.6e-42 144.7 26.1 2.5e-24 86.5 4.6 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36104.1 - 2.6e-42 144.7 17.8 8.9e-23 81.5 0.7 2.2 2 0 0 2 2 2 2 SRS domain Ig_5 PF16681.5 PFH36104.1 - 0.029 14.8 0.0 0.13 12.7 0.0 2.1 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain zf-C2HC_2 PF13913.6 PFH36105.1 - 0.0001 22.1 1.6 0.0001 22.1 1.6 2.7 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 PFH36105.1 - 0.41 11.2 0.1 0.41 11.2 0.1 2.8 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PFH36105.1 - 0.68 10.9 4.8 2.1 9.4 0.6 3.5 2 1 1 3 3 3 0 C2H2-type zinc finger ParA PF10609.9 PFH36107.1 - 3.2e-86 288.8 0.1 4.1e-86 288.4 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 PFH36107.1 - 3.6e-11 43.2 0.0 6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 PFH36107.1 - 2.1e-09 37.5 0.2 2.2e-08 34.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 PFH36107.1 - 8e-05 22.0 0.6 0.00038 19.8 0.1 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 PFH36107.1 - 0.00015 21.4 0.0 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 PFH36107.1 - 0.0008 19.3 1.8 0.01 15.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 PFH36107.1 - 0.0012 17.9 0.1 0.0019 17.2 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 PFH36107.1 - 0.0013 18.6 0.1 0.0026 17.7 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase MipZ PF09140.11 PFH36107.1 - 0.002 17.5 0.1 0.0056 16.0 0.1 1.7 1 1 0 1 1 1 1 ATPase MipZ NB-ARC PF00931.22 PFH36107.1 - 0.0028 16.9 0.1 0.0043 16.3 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain CBP_BcsQ PF06564.12 PFH36107.1 - 0.0032 17.0 0.1 0.013 15.0 0.1 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ DAP3 PF10236.9 PFH36107.1 - 0.024 13.8 0.3 0.038 13.2 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 PFH36107.1 - 0.037 14.4 0.0 0.096 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 PFH36107.1 - 0.039 13.7 0.2 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 PFH36107.1 - 0.044 13.2 0.3 0.25 10.8 0.1 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PIF1 PF05970.14 PFH36107.1 - 0.067 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase CLP1_P PF16575.5 PFH36107.1 - 0.12 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 PFH36107.1 - 0.13 12.0 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein SRP54 PF00448.22 PFH36107.1 - 0.15 11.6 0.5 0.28 10.8 0.1 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 PFH36107.1 - 0.19 11.7 0.1 0.35 10.9 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Peptidase_S24 PF00717.23 PFH36108.1 - 1.5e-11 44.1 0.4 2.6e-11 43.3 0.4 1.4 1 0 0 1 1 1 1 Peptidase S24-like Pkinase PF00069.25 PFH36109.1 - 2.5e-20 73.0 0.0 5e-20 72.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 PFH36109.1 - 6.9e-17 61.7 0.0 1.4e-16 60.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH36109.1 - 9.7e-06 25.0 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH36109.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 PFH36109.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Herpes_capsid PF06112.11 PFH36109.1 - 0.3 11.1 4.1 0.15 12.1 1.1 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein ER PF01133.17 PFH36111.1 - 8.3e-42 141.2 0.6 9.3e-42 141.0 0.6 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Imm6 PF14434.6 PFH36111.1 - 0.048 13.6 0.1 0.12 12.3 0.0 1.6 1 1 1 2 2 2 0 Immunity protein Imm6 UQ_con PF00179.26 PFH36112.1 - 3.3e-36 124.0 0.0 4.4e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PFH36112.1 - 0.2 11.5 0.1 0.41 10.5 0.1 1.4 1 0 0 1 1 1 0 UEV domain RCC1 PF00415.18 PFH36113.1 - 2.3e-32 111.4 2.4 2e-09 37.9 0.0 6.0 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH36113.1 - 2e-24 84.8 11.5 1.8e-07 30.8 0.4 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Golgin_A5 PF09787.9 PFH36113.1 - 0.0029 17.1 14.8 0.0029 17.1 14.8 6.2 3 1 3 6 6 6 3 Golgin subfamily A member 5 ABC_membrane PF00664.23 PFH36114.1 - 8.9e-86 287.9 15.5 3.3e-51 174.6 4.3 2.4 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PFH36114.1 - 8.4e-48 162.4 0.0 2.8e-31 108.8 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PFH36114.1 - 4.2e-07 29.6 2.1 2.2e-05 24.0 0.1 3.2 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PFH36114.1 - 4.8e-06 26.6 0.0 0.019 14.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 PFH36114.1 - 7.7e-06 25.6 0.1 1.6 8.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 PFH36114.1 - 2.7e-05 24.2 0.1 0.083 13.0 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 PFH36114.1 - 3.8e-05 24.0 1.1 0.21 11.8 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 PFH36114.1 - 0.00016 21.3 0.1 0.35 10.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 PFH36114.1 - 0.00033 21.1 5.8 0.14 12.5 0.0 4.0 3 2 1 4 4 4 1 AAA ATPase domain AAA_5 PF07728.14 PFH36114.1 - 0.002 18.1 0.2 1.2 9.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 PFH36114.1 - 0.0046 16.9 0.2 0.26 11.2 0.0 2.9 3 0 0 3 3 3 1 Rad17 P-loop domain FeoB_N PF02421.18 PFH36114.1 - 0.0047 16.5 0.1 1.3 8.6 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_21 PF13304.6 PFH36114.1 - 0.0073 16.2 0.2 0.36 10.6 0.0 2.8 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 PFH36114.1 - 0.0094 15.5 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 PFH36114.1 - 0.013 15.2 1.8 2.5 7.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 PFH36114.1 - 0.027 15.0 0.2 6.8 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PFH36114.1 - 0.033 14.6 1.3 14 6.2 1.5 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 PFH36114.1 - 0.034 13.9 0.0 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 PFH36114.1 - 0.036 14.2 0.1 16 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 PFH36114.1 - 0.076 12.3 0.6 1.1 8.5 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin ATP-synt_ab PF00006.25 PFH36114.1 - 0.082 12.5 2.0 3 7.4 0.0 2.9 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.20 PFH36114.1 - 0.086 12.7 0.2 5.9 6.8 0.1 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.18 PFH36114.1 - 0.098 12.4 0.1 4.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 PFH36114.1 - 0.1 11.8 0.0 1.7 7.7 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit SbcCD_C PF13558.6 PFH36114.1 - 0.15 12.4 0.2 1.4 9.2 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 PFH36114.1 - 0.15 12.5 0.0 4.7 7.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 PFH36114.1 - 0.16 11.7 0.4 3.7 7.2 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 PFH36114.1 - 0.17 11.1 0.1 20 4.3 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 PFH36114.1 - 0.19 11.4 0.0 9.5 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 PFH36114.1 - 0.25 10.8 1.3 0.56 9.7 0.1 2.0 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_14 PF13173.6 PFH36114.1 - 0.25 11.3 0.6 58 3.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 PFH36114.1 - 0.34 10.8 1.8 9.9 6.0 0.0 3.0 3 0 0 3 3 3 0 NACHT domain Dus PF01207.17 PFH36115.1 - 4.7e-49 167.2 0.0 2.4e-48 164.8 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) PA28_alpha PF02251.18 PFH36115.1 - 0.19 11.8 0.1 0.39 10.8 0.1 1.5 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Gpi1 PF05024.15 PFH36116.1 - 1.7e-36 126.1 3.7 2.1e-25 89.9 1.0 2.2 2 0 0 2 2 2 2 N-acetylglucosaminyl transferase component (Gpi1) SNF2_N PF00176.23 PFH36117.1 - 6.8e-65 219.1 0.9 6.8e-65 219.1 0.9 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PFH36117.1 - 4.8e-19 68.7 0.0 1.5e-18 67.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 PFH36117.1 - 0.0015 18.8 5.7 0.0015 18.8 5.7 4.5 4 0 0 4 4 4 1 HSA Methyltrans_RNA PF04452.14 PFH36117.1 - 4.2 6.6 8.1 0.17 11.2 1.7 1.9 2 0 0 2 2 2 0 RNA methyltransferase PilJ PF13675.6 PFH36119.1 - 0.0071 16.4 1.7 0.54 10.3 0.9 2.4 1 1 1 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term Pil1 PF13805.6 PFH36119.1 - 0.061 12.8 4.9 0.082 12.4 4.9 1.2 1 0 0 1 1 1 0 Eisosome component PIL1 DUF5420 PF17457.2 PFH36119.1 - 0.093 12.6 0.7 0.21 11.4 0.6 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5420) Phage_GP20 PF06810.11 PFH36119.1 - 0.19 11.5 6.3 0.42 10.4 6.3 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 5_3_exonuc PF01367.20 PFH36119.1 - 0.34 11.6 3.3 1.5 9.4 3.2 2.1 2 1 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold PHM7_cyt PF14703.6 PFH36119.1 - 0.59 10.4 8.0 1.3 9.2 5.7 2.1 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF4315 PF14193.6 PFH36119.1 - 2.2 8.3 10.5 1.2 9.2 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) FapA PF03961.13 PFH36119.1 - 4.2 5.9 7.8 5.2 5.6 7.2 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A DHR10 PF18595.1 PFH36119.1 - 5.6 7.1 11.9 0.83 9.7 4.6 2.7 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain XhlA PF10779.9 PFH36119.1 - 8.5 6.7 9.0 51 4.2 0.1 3.3 3 1 0 4 4 4 0 Haemolysin XhlA UPF0242 PF06785.11 PFH36119.1 - 9.4 6.3 10.4 5.3 7.1 8.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GDI PF00996.18 PFH36120.1 - 3e-19 68.9 0.0 4.2e-09 35.4 0.0 3.3 3 0 0 3 3 3 3 GDP dissociation inhibitor NAD_binding_8 PF13450.6 PFH36120.1 - 1.7e-05 24.9 0.4 7.2e-05 22.9 0.4 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 PFH36120.1 - 0.0024 17.3 0.5 0.0036 16.7 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 PFH36120.1 - 0.028 15.0 0.1 0.053 14.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PFH36120.1 - 0.22 10.7 0.2 0.46 9.7 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Abhydrolase_1 PF00561.20 PFH36122.1 - 5.6e-36 124.5 0.0 1.7e-35 122.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 PFH36122.1 - 1.5e-06 28.1 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 PFH36122.1 - 0.0013 19.4 2.1 0.0023 18.6 2.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PFH36122.1 - 0.0028 17.0 0.1 0.006 15.9 0.1 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PFH36122.1 - 0.031 13.8 0.4 3.7 6.9 0.2 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family AP2 PF00847.20 PFH36125.1 - 2.5e-14 53.2 2.5 2.5e-14 53.2 2.5 1.7 2 0 0 2 2 2 1 AP2 domain SNAP PF14938.6 PFH36126.1 - 5.1e-17 62.2 8.5 1.6e-16 60.6 8.6 1.7 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP DHR-2 PF06920.13 PFH36126.1 - 5.9e-05 21.9 0.0 7.6e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Dock homology region 2 TPR_12 PF13424.6 PFH36126.1 - 0.00099 19.4 7.5 3.2 8.1 0.7 4.2 2 2 1 3 3 3 2 Tetratricopeptide repeat ZapD PF07072.11 PFH36126.1 - 0.0025 17.6 0.5 0.014 15.2 0.0 2.3 2 1 1 3 3 3 1 Cell division protein TPR_10 PF13374.6 PFH36126.1 - 0.0062 16.4 2.1 33 4.5 0.1 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 PFH36126.1 - 4.9 8.2 13.8 34 5.6 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat Vps16_N PF04841.13 PFH36128.1 - 2.4e-54 184.7 0.0 2.9e-30 105.4 0.0 2.2 2 0 0 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.12 PFH36128.1 - 2e-46 158.6 0.0 2.8e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Ank_4 PF13637.6 PFH36129.1 - 1.4e-06 28.7 0.5 0.031 14.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH36129.1 - 0.00012 22.2 1.5 0.41 11.4 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PFH36129.1 - 0.00055 20.2 0.3 0.055 13.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PFH36129.1 - 0.021 15.4 0.1 15 6.2 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Methyltransf_25 PF13649.6 PFH36129.1 - 0.067 13.9 0.0 0.61 10.8 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain Ank PF00023.30 PFH36129.1 - 0.068 13.6 4.0 0.29 11.7 0.1 3.2 3 0 0 3 3 3 0 Ankyrin repeat Pro_isomerase PF00160.21 PFH36130.1 - 5.5e-53 179.5 0.2 1.6e-52 178.0 0.2 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 PFH36130.1 - 1.1e-08 35.6 0.6 0.0084 16.9 0.2 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 PFH36130.1 - 0.0029 16.6 0.0 0.09 11.7 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 PFH36130.1 - 0.0078 16.5 0.0 0.34 11.2 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DNase_NucA_NucB PF14040.6 PFH36130.1 - 0.27 11.6 1.7 0.63 10.4 1.7 1.6 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB Choline_kinase PF01633.20 PFH36131.1 - 2.9e-41 141.4 0.0 2.5e-20 73.0 0.0 2.1 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 PFH36131.1 - 1.8e-13 51.0 0.5 1.7e-12 47.8 0.5 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family TGT PF01702.18 PFH36132.1 - 9.3e-98 327.6 0.0 2.2e-69 234.2 0.0 3.0 2 1 0 2 2 2 2 Queuine tRNA-ribosyltransferase SAC3_GANP PF03399.16 PFH36133.1 - 2.1e-12 47.0 0.1 4.5e-05 23.0 0.0 3.6 4 0 0 4 4 4 3 SAC3/GANP family Amidase_5 PF05382.13 PFH36133.1 - 0.12 12.3 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase DUF2190 PF09956.9 PFH36133.1 - 0.14 12.6 0.1 0.44 11.1 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) CSD PF00313.22 PFH36134.1 - 7e-23 80.3 1.2 9.5e-23 79.8 1.2 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 PFH36134.1 - 0.00076 19.1 0.3 0.0017 18.0 0.3 1.7 1 1 0 1 1 1 1 Ribonuclease B OB domain FAST_1 PF06743.15 PFH36135.1 - 0.057 13.4 6.7 0.31 11.0 0.0 4.4 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 1 Glyco_hydro_35 PF01301.19 PFH36136.1 - 1.7e-15 57.5 0.0 2.3e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Streptin-Immun PF11083.8 PFH36138.1 - 0.0032 17.8 0.2 0.0032 17.8 0.2 3.0 3 0 0 3 3 3 1 Lantibiotic streptin immunity protein OmpH PF03938.14 PFH36138.1 - 0.023 15.0 13.0 0.035 14.4 6.9 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.12 PFH36138.1 - 0.84 9.7 10.5 0.18 11.8 6.3 1.9 2 0 0 2 2 2 0 Laminin Domain II ExsD PF16806.5 PFH36138.1 - 1.4 8.8 8.1 2.8 7.8 0.2 2.5 2 1 1 3 3 3 0 Antiactivator protein ExsD TadF PF16964.5 PFH36138.1 - 1.5 8.5 5.9 0.66 9.7 0.6 2.3 1 1 1 2 2 2 0 Putative tight adherence pilin protein F Exonuc_VII_L PF02601.15 PFH36138.1 - 3.1 7.3 10.9 15 5.1 10.9 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit TEX13 PF15186.6 PFH36138.1 - 4 7.1 9.6 0.74 9.5 4.0 2.2 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family IZUMO PF15005.6 PFH36138.1 - 5.8 7.4 6.9 1.5 9.3 1.2 2.4 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated GTP_EFTU PF00009.27 PFH36139.1 - 1.1e-44 152.3 0.0 1.5e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PFH36139.1 - 4.4e-28 97.8 0.1 1.5e-27 96.1 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PFH36139.1 - 1.1e-08 35.3 0.2 3.6e-08 33.7 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PAM2 PF07145.15 PFH36139.1 - 0.0025 17.4 1.1 0.0066 16.1 0.2 2.2 2 0 0 2 2 2 1 Ataxin-2 C-terminal region MMR_HSR1 PF01926.23 PFH36139.1 - 0.0035 17.4 0.0 0.021 14.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase p25-alpha PF05517.12 PFH36140.1 - 2.2e-38 131.9 1.2 2.4e-38 131.7 1.2 1.0 1 0 0 1 1 1 1 p25-alpha G-alpha PF00503.20 PFH36140.1 - 0.098 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Plasmodium_HRP PF05403.11 PFH36142.1 - 0.0013 18.6 8.6 0.0029 17.4 8.6 1.5 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) CT47 PF15623.6 PFH36143.1 - 0.042 13.7 50.1 4.6 7.0 1.3 7.4 7 0 0 7 7 7 0 Cancer/testis gene family 47 DUF1308 PF07000.11 PFH36144.1 - 2.2e-15 57.0 0.0 3.8e-15 56.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) Patched PF02460.18 PFH36147.1 - 1.5e-85 287.9 9.5 2.7e-44 151.5 12.7 2.5 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 PFH36147.1 - 9.9e-28 96.9 0.2 9.9e-28 96.9 0.2 3.4 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 PFH36147.1 - 3.4e-05 21.7 21.5 5.5e-05 21.1 21.5 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF2852 PF11014.8 PFH36147.1 - 0.043 14.0 1.2 16 5.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) SecD_SecF PF02355.16 PFH36147.1 - 0.63 9.4 18.1 0.12 11.7 14.0 1.9 2 0 0 2 2 2 0 Protein export membrane protein Lactamase_B_2 PF12706.7 PFH36148.1 - 7e-33 113.8 0.1 1.2e-32 113.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 PFH36148.1 - 6.6e-11 42.4 0.0 1.2e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PFH36148.1 - 0.17 11.9 1.6 0.51 10.3 1.6 1.8 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Ras PF00071.22 PFH36149.1 - 3.8e-50 169.6 0.0 4.5e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH36149.1 - 3.3e-31 108.0 0.0 5.7e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH36149.1 - 1.2e-11 44.4 0.0 1.4e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PFH36149.1 - 2.1e-05 24.0 0.0 2.5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PFH36149.1 - 0.0002 20.9 0.0 0.00061 19.4 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PFH36149.1 - 0.00052 20.1 0.0 0.00077 19.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 PFH36149.1 - 0.13 11.7 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 PFH36149.1 - 0.19 11.2 0.0 0.4 10.1 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_membrane PF00664.23 PFH36151.1 - 3.4e-55 187.6 23.3 4.2e-31 108.6 8.8 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 PFH36151.1 - 5.5e-47 159.7 0.0 2e-28 99.6 0.0 3.5 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.19 PFH36151.1 - 1.7e-07 30.9 0.0 0.056 12.9 0.0 3.3 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PFH36151.1 - 3.4e-05 23.5 0.3 0.094 12.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 PFH36151.1 - 0.00037 20.4 0.6 11 5.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 PFH36151.1 - 0.0011 18.6 2.3 0.42 10.2 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 PFH36151.1 - 0.0011 19.3 0.6 1.2 9.5 0.1 3.2 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 PFH36151.1 - 0.0022 17.1 0.6 1.8 7.6 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 PFH36151.1 - 0.0031 17.1 1.7 2.2 7.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 PFH36151.1 - 0.0032 17.4 0.1 3.2 7.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 PFH36151.1 - 0.0062 16.9 6.9 3.5 8.0 0.0 4.0 2 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 PFH36151.1 - 0.0085 16.0 0.7 0.07 13.0 0.0 2.6 3 0 0 3 3 3 1 NTPase MMR_HSR1 PF01926.23 PFH36151.1 - 0.0085 16.2 0.7 0.54 10.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 PFH36151.1 - 0.093 12.1 1.1 11 5.3 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 PFH36151.1 - 0.099 11.9 0.3 0.63 9.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 PFH36151.1 - 0.12 12.9 2.9 5.5 7.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 PFH36151.1 - 0.22 11.2 3.8 8 6.1 0.4 3.3 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 PFH36151.1 - 0.5 10.4 4.2 11 6.0 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 PFH36151.1 - 3.6 7.5 5.0 16 5.4 0.2 3.3 3 0 0 3 3 3 0 NACHT domain RRS1 PF04939.12 PFH36152.1 - 1.3e-46 158.4 1.7 1.3e-46 158.4 1.7 2.1 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) Imm70 PF15601.6 PFH36152.1 - 0.0061 16.1 0.2 0.064 12.8 0.0 2.2 2 0 0 2 2 2 1 Immunity protein 70 N-SET PF11764.8 PFH36152.1 - 6.7 6.8 11.5 26 4.9 11.3 2.0 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N XRN_N PF03159.18 PFH36153.1 - 7.6e-30 104.1 0.0 2.4e-23 82.8 0.0 2.3 2 0 0 2 2 2 2 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PFH36153.1 - 5.8e-05 22.2 0.0 0.0003 19.9 0.0 2.0 2 0 0 2 2 2 1 Xrn1 helical domain MA3 PF02847.17 PFH36154.1 - 6.4e-18 64.8 1.7 1.3e-17 63.8 1.7 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 PFH36154.1 - 9.3e-12 45.0 0.2 9.3e-12 45.0 0.2 2.4 3 0 0 3 3 3 1 MIF4G domain SNF2_N PF00176.23 PFH36155.1 - 4.7e-66 222.9 0.0 9.2e-66 221.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PFH36155.1 - 7.1e-19 68.2 0.0 7.5e-18 64.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 PFH36155.1 - 5.2e-12 45.5 0.2 1.1e-11 44.5 0.2 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 PFH36155.1 - 1.2e-07 31.9 0.0 3.8e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PFH36155.1 - 3.6e-05 23.6 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SnAC PF14619.6 PFH36155.1 - 4.8e-05 23.9 2.7 4.8e-05 23.9 2.7 4.2 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Nucleoside_tran PF01733.18 PFH36158.1 - 1e-06 28.4 2.6 0.54 9.6 0.5 5.1 5 0 0 5 5 5 3 Nucleoside transporter Wzy_C PF04932.15 PFH36159.1 - 0.031 13.9 0.1 0.031 13.9 0.1 2.1 2 0 0 2 2 2 0 O-Antigen ligase Rieske PF00355.26 PFH36160.1 - 3.8e-10 39.6 0.1 6.4e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain WD40 PF00400.32 PFH36161.1 - 5.6e-39 131.4 6.4 3.7e-08 33.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Prp19 PF08606.11 PFH36161.1 - 1.6e-30 104.9 3.7 4.7e-30 103.4 3.7 1.9 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 PFH36161.1 - 4.4e-15 55.7 0.0 0.0051 17.1 0.0 5.3 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PFH36161.1 - 0.00012 20.9 0.4 0.003 16.3 0.0 2.7 2 1 1 3 3 3 1 Nucleoporin Nup120/160 U-box PF04564.15 PFH36161.1 - 0.0011 19.1 0.0 0.0029 17.7 0.0 1.7 1 0 0 1 1 1 1 U-box domain Ge1_WD40 PF16529.5 PFH36161.1 - 0.0032 16.5 0.0 0.088 11.7 0.0 2.7 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein HOOK PF05622.12 PFH36161.1 - 0.012 13.8 5.9 0.017 13.3 5.9 1.1 1 0 0 1 1 1 0 HOOK protein zf-Nse PF11789.8 PFH36161.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SAG PF04092.13 PFH36162.1 - 1.5e-49 168.2 10.8 9.1e-25 88.0 5.6 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36163.1 - 7.2e-47 159.5 12.6 3.3e-23 82.9 4.2 2.1 2 0 0 2 2 2 2 SRS domain PCSK9_C3 PF18463.1 PFH36163.1 - 0.068 13.4 0.1 4.6 7.5 0.0 2.8 2 0 0 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Htr2 PF17909.1 PFH36163.1 - 0.13 12.6 1.9 0.24 11.7 1.9 1.3 1 0 0 1 1 1 0 Htr2 transmembrane domain MRP_L53 PF10780.9 PFH36163.1 - 0.25 11.5 3.5 6.3 7.1 0.0 3.2 3 0 0 3 3 3 0 39S ribosomal protein L53/MRP-L53 SAG PF04092.13 PFH36164.1 - 9.9e-51 172.0 12.7 3.2e-25 89.4 4.1 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36165.1 - 7.6e-50 169.1 5.6 1e-24 87.8 1.4 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36166.1 - 1.7e-46 158.3 16.6 5.9e-23 82.1 7.4 2.5 2 1 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36167.1 - 6.5e-46 156.4 11.7 3.4e-23 82.9 5.0 2.1 2 0 0 2 2 2 2 SRS domain MRP_L53 PF10780.9 PFH36167.1 - 1.2 9.4 6.1 9.3 6.5 0.0 3.7 4 0 0 4 4 4 0 39S ribosomal protein L53/MRP-L53 SAG PF04092.13 PFH36168.1 - 6.1e-45 153.2 11.6 2.1e-23 83.6 0.1 2.3 2 0 0 2 2 2 2 SRS domain MRP_L53 PF10780.9 PFH36168.1 - 0.077 13.2 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 SAG PF04092.13 PFH36169.1 - 2.1e-72 242.1 23.0 3e-23 83.1 0.7 4.1 3 1 1 4 4 4 4 SRS domain SAG PF04092.13 PFH36170.1 - 3.8e-46 157.2 6.2 1.4e-23 84.2 0.1 2.1 2 0 0 2 2 2 2 SRS domain MRP_L53 PF10780.9 PFH36170.1 - 0.11 12.7 1.3 0.99 9.6 0.1 2.7 3 0 0 3 3 3 0 39S ribosomal protein L53/MRP-L53 SAG PF04092.13 PFH36171.1 - 6.2e-42 143.5 19.7 2.3e-21 77.0 14.0 2.1 2 0 0 2 2 2 2 SRS domain CHCH PF06747.13 PFH36171.1 - 0.1 12.8 0.2 5.8 7.2 0.1 2.5 2 0 0 2 2 2 0 CHCH domain SAG PF04092.13 PFH36172.1 - 2e-45 154.8 14.8 1.8e-23 83.8 1.5 2.1 2 0 0 2 2 2 2 SRS domain GABP-alpha PF11620.8 PFH36172.1 - 0.19 12.0 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 GA-binding protein alpha chain SAG PF04092.13 PFH36174.1 - 1.8e-45 155.0 17.7 1.3e-24 87.5 2.2 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36175.1 - 8.1e-43 146.4 7.9 2.5e-20 73.6 0.0 2.1 2 0 0 2 2 2 2 SRS domain CHCH PF06747.13 PFH36175.1 - 0.13 12.5 0.3 0.37 11.0 0.3 1.8 1 0 0 1 1 1 0 CHCH domain SAG PF04092.13 PFH36176.1 - 3e-45 154.2 14.6 5.2e-25 88.7 4.0 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36177.1 - 4.7e-09 37.1 0.0 5.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH36178.1 - 1.3e-47 161.9 14.3 1.2e-24 87.5 2.2 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36179.1 - 9.3e-48 162.4 10.7 1.7e-24 87.1 0.5 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36180.1 - 1.5e-47 161.7 12.3 3.8e-26 92.4 0.8 2.2 2 0 0 2 2 2 2 SRS domain GTP_EFTU PF00009.27 PFH36181.1 - 4.6e-22 78.5 0.0 2.7e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 PFH36181.1 - 0.00027 20.8 0.0 0.72 9.6 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU_D3 PF03143.17 PFH36181.1 - 0.0014 18.9 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 PFH36181.1 - 0.0054 16.5 0.0 4.3 7.1 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D2 PF03144.25 PFH36181.1 - 0.029 14.8 0.1 0.091 13.2 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 2 UCR_hinge PF02320.16 PFH36182.1 - 2e-19 69.5 2.2 2.4e-19 69.3 2.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein XTBD PF11952.8 PFH36183.1 - 5e-06 26.2 0.4 7.1e-06 25.7 0.4 1.2 1 0 0 1 1 1 1 XRN-Two Binding Domain, XTBD HIT PF01230.23 PFH36184.1 - 2.2e-21 76.4 0.0 3.5e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 PFH36184.1 - 1.7e-08 35.0 0.0 2.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding PCNA_N PF00705.18 PFH36185.1 - 3.1e-24 85.1 0.2 5.9e-24 84.2 0.2 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 PFH36185.1 - 1.2e-12 48.1 0.0 6e-12 45.8 0.0 2.0 1 1 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 PFH36185.1 - 2.3e-05 24.0 0.1 5e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Rad9 DNA_pol3_beta_2 PF02767.16 PFH36185.1 - 0.061 13.6 0.3 0.16 12.2 0.1 1.8 2 1 0 2 2 2 0 DNA polymerase III beta subunit, central domain BNIP2 PF12496.8 PFH36185.1 - 0.67 10.4 7.4 2.3 8.7 3.3 2.3 1 1 1 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 RRM_1 PF00076.22 PFH36186.1 - 1.2e-47 159.6 0.0 2.4e-16 59.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PFH36186.1 - 3.3e-07 30.2 0.0 0.014 15.4 0.0 2.9 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 PFH36186.1 - 1.4e-05 25.0 0.0 0.49 10.2 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF1866) RNA_bind PF08675.11 PFH36186.1 - 7e-05 22.8 0.5 0.63 10.1 0.1 3.4 3 0 0 3 3 3 2 RNA binding domain RRM_5 PF13893.6 PFH36186.1 - 0.00023 20.7 0.0 0.01 15.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH36186.1 - 0.0013 18.8 0.1 17 5.6 0.0 3.6 3 1 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 PFH36186.1 - 0.0017 18.6 0.0 12 6.1 0.0 4.2 3 2 2 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 PFH36186.1 - 0.0018 18.3 0.0 0.27 11.4 0.0 2.5 2 0 0 2 2 2 1 Limkain b1 KH_1 PF00013.29 PFH36188.1 - 0.044 13.6 0.1 0.35 10.7 0.1 2.4 3 0 0 3 3 3 0 KH domain MAT1 PF06391.13 PFH36189.1 - 1.1e-13 51.5 8.9 1.4e-13 51.2 8.9 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_2 PF13639.6 PFH36189.1 - 0.00012 22.3 8.3 0.00019 21.7 8.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PFH36189.1 - 0.00038 20.3 9.3 0.00068 19.5 9.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_5 PF17121.5 PFH36189.1 - 0.0011 18.8 8.3 0.012 15.5 5.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PFH36189.1 - 0.0071 16.2 5.7 0.028 14.3 6.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PFH36189.1 - 0.0073 16.1 7.7 0.016 15.0 7.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH36189.1 - 0.013 15.5 8.1 0.043 13.8 4.6 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-4CXXC_R1 PF10497.9 PFH36189.1 - 0.024 14.8 5.4 0.13 12.5 0.4 2.4 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_4 PF14570.6 PFH36189.1 - 0.085 12.7 5.0 0.21 11.4 5.0 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Sun2_CC2 PF18580.1 PFH36189.1 - 0.09 13.0 0.5 0.17 12.1 0.5 1.4 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 zf-C3HC4_2 PF13923.6 PFH36189.1 - 0.47 10.4 9.9 3.1 7.7 8.0 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DnaJ PF00226.31 PFH36190.1 - 1.1e-05 25.4 0.0 4e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain Ribosomal_L5e PF17144.4 PFH36191.1 - 6.1e-81 270.2 0.6 1.2e-80 269.3 0.6 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 PFH36191.1 - 3.8e-33 114.3 7.6 3.8e-33 114.3 7.6 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF4853 PF16145.5 PFH36191.1 - 0.0075 16.4 0.2 0.039 14.1 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4853) CHORD PF04968.12 PFH36192.1 - 1.4e-46 157.0 25.9 2.2e-23 82.7 11.6 2.2 2 0 0 2 2 2 2 CHORD MFS_1 PF07690.16 PFH36194.1 - 4.3e-13 48.9 17.6 4.3e-13 48.9 17.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ABM PF03992.16 PFH36195.1 - 0.077 13.1 0.1 0.58 10.3 0.0 2.4 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase DUF2431 PF10354.9 PFH36196.1 - 0.00022 21.6 0.0 0.00031 21.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) DUF4227 PF14004.6 PFH36196.1 - 0.2 11.7 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) Pkinase PF00069.25 PFH36198.1 - 0.015 14.7 0.0 0.34 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain HEAT PF02985.22 PFH36198.1 - 1.6 9.2 12.2 28 5.3 0.1 5.5 5 0 0 5 5 5 0 HEAT repeat TSP_1 PF00090.19 PFH36199.1 - 2.5e-08 34.0 11.2 0.00024 21.2 2.5 3.1 2 0 0 2 2 2 2 Thrombospondin type 1 domain DUF3357 PF11837.8 PFH36199.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.7 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) Peptidase_S8 PF00082.22 PFH36200.1 - 4.1e-15 55.8 1.5 6e-15 55.3 1.5 1.2 1 0 0 1 1 1 1 Subtilase family DUF2970 PF11174.8 PFH36200.1 - 0.017 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) DUF4235 PF14019.6 PFH36200.1 - 0.02 15.0 1.9 3.4 7.8 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) Fcf1 PF04900.12 PFH36202.1 - 6.6e-35 119.5 2.6 6.6e-35 119.5 2.6 1.6 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 PFH36202.1 - 7.7e-12 45.6 0.1 1.5e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 PFH36202.1 - 0.035 14.4 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 NTF2 fold immunity protein V-SNARE_C PF12352.8 PFH36204.1 - 9.2e-09 35.5 11.1 0.00012 22.3 0.8 2.3 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 PFH36204.1 - 0.0001 22.2 2.8 0.041 13.8 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5089) NPV_P10 PF05531.12 PFH36204.1 - 0.013 16.0 8.7 0.053 14.0 0.4 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec20 PF03908.13 PFH36204.1 - 0.022 14.7 5.8 0.026 14.4 0.6 2.2 2 0 0 2 2 2 0 Sec20 Phage_HK97_TLTM PF06120.11 PFH36204.1 - 0.072 12.3 4.6 0.1 11.8 2.0 2.0 2 0 0 2 2 2 0 Tail length tape measure protein DUF948 PF06103.11 PFH36204.1 - 0.076 13.3 4.8 1.9 8.8 0.4 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 PFH36204.1 - 0.19 11.8 6.7 1 9.4 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DASH_Duo1 PF08651.10 PFH36204.1 - 0.25 11.2 7.0 4.9 7.0 1.9 2.5 2 1 0 2 2 2 0 DASH complex subunit Duo1 Spc7 PF08317.11 PFH36204.1 - 0.82 8.5 9.5 3.1 6.6 3.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.12 PFH36204.1 - 0.89 9.6 8.3 3.4 7.7 1.2 2.6 2 1 1 3 3 3 0 Laminin Domain II WXG100 PF06013.12 PFH36204.1 - 2.3 8.5 9.3 2.1 8.6 3.0 3.0 2 2 0 2 2 2 0 Proteins of 100 residues with WXG DUF16 PF01519.16 PFH36204.1 - 2.5 8.7 9.8 13 6.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 Vps54_N PF10475.9 PFH36204.1 - 4.9 6.3 7.9 3.7 6.8 0.2 2.1 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex SAPS PF04499.15 PFH36205.1 - 9.9e-09 34.5 0.0 1.5e-05 24.0 0.0 2.8 2 1 0 2 2 2 2 SIT4 phosphatase-associated protein 2-oxoacid_dh PF00198.23 PFH36207.1 - 4e-71 239.2 0.1 5.3e-71 238.8 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PFH36207.1 - 1.4e-17 63.3 0.2 2.6e-17 62.4 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 PFH36207.1 - 3.9e-13 49.5 0.7 1.3e-12 47.8 0.2 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 PFH36207.1 - 0.0048 16.7 0.2 0.016 15.0 0.2 1.9 1 0 0 1 1 1 1 Biotin-lipoyl like GCV_H PF01597.19 PFH36207.1 - 0.023 14.6 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_D23 PF16576.5 PFH36207.1 - 0.079 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion MSA-2c PF12238.8 PFH36207.1 - 0.17 11.8 4.6 0.4 10.7 0.3 2.4 2 0 0 2 2 2 0 Merozoite surface antigen 2c DUF3597 PF12200.8 PFH36207.1 - 8.2 7.0 6.3 30 5.1 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) WD40 PF00400.32 PFH36208.1 - 7.5e-07 29.8 3.3 0.55 11.2 0.5 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat EGF PF00008.27 PFH36211.1 - 5.4e-18 65.0 94.3 0.00077 19.7 4.9 9.0 7 4 0 7 7 7 7 EGF-like domain hEGF PF12661.7 PFH36211.1 - 3.6e-14 52.8 81.6 0.004 17.7 4.5 10.0 9 2 0 9 9 9 7 Human growth factor-like EGF FXa_inhibition PF14670.6 PFH36211.1 - 1.1e-10 41.6 82.8 0.089 13.1 3.7 7.8 6 1 1 7 7 7 7 Coagulation Factor Xa inhibitory site cEGF PF12662.7 PFH36211.1 - 2.6e-08 33.7 85.2 0.0038 17.1 0.9 9.2 9 2 0 9 9 9 7 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 PFH36211.1 - 7.1e-05 23.0 66.0 0.044 14.1 3.0 7.4 7 0 0 7 7 7 5 Pvs28 EGF domain EGF_CA PF07645.15 PFH36211.1 - 0.24 11.7 81.8 1.6 9.0 7.4 8.2 5 2 2 7 7 7 0 Calcium-binding EGF domain Sporozoite_P67 PF05642.11 PFH36212.1 - 6.8e-05 21.2 0.1 6.8e-05 21.2 0.1 2.7 1 1 1 2 2 2 1 Sporozoite P67 surface antigen Presenilin PF01080.17 PFH36212.1 - 0.17 10.6 5.6 0.2 10.4 5.6 1.2 1 0 0 1 1 1 0 Presenilin CCSAP PF15748.5 PFH36212.1 - 2.7 8.1 10.3 4 7.5 10.3 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated MORN PF02493.20 PFH36213.1 - 1.2e-34 116.1 51.3 1.3e-05 24.8 0.8 11.1 11 0 0 11 11 11 8 MORN repeat Avl9 PF09794.9 PFH36213.1 - 1.4e-22 80.0 0.0 2.3e-10 39.7 0.0 3.8 3 1 1 4 4 4 3 Transport protein Avl9 DENN PF02141.21 PFH36213.1 - 0.0021 18.0 0.2 0.0038 17.2 0.2 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain UQ_con PF00179.26 PFH36214.1 - 1.5e-54 183.5 0.0 1.7e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PFH36214.1 - 6.4e-05 22.7 0.0 8.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 PFH36214.1 - 0.0055 17.0 0.0 0.0067 16.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 PFH36214.1 - 0.022 14.6 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain DNA_pol_B_exo1 PF03104.19 PFH36215.1 - 9.7e-47 159.7 0.0 1.4e-46 159.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.12 PFH36215.1 - 3.8e-16 58.7 0.0 6.2e-14 51.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1744) DNA_pol_B PF00136.21 PFH36215.1 - 2.5e-09 36.4 1.0 5.5e-06 25.4 0.1 3.5 4 0 0 4 4 4 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 PFH36215.1 - 2.1e-05 24.3 0.0 5.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 PFH36215.1 - 0.0017 18.4 1.0 0.0036 17.3 0.0 2.1 2 0 0 2 2 2 1 RNase_H superfamily Keratin_B2_2 PF13885.6 PFH36215.1 - 5.2 7.1 36.6 15 5.7 36.6 1.7 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein RRM_1 PF00076.22 PFH36216.1 - 2.1e-06 27.4 0.0 0.0065 16.3 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSB_motif PF16294.5 PFH36216.1 - 2.1 8.7 6.0 7.7 6.8 6.0 1.9 1 1 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif DUF1509 PF07420.11 PFH36216.1 - 9.7 5.0 15.0 15 4.4 15.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) MFS_5 PF05631.14 PFH36217.1 - 4.5e-52 177.1 1.9 3.8e-40 137.9 0.3 2.1 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 PFH36217.1 - 6.4e-12 45.1 16.6 2.8e-11 42.9 1.2 2.6 3 1 0 3 3 3 2 Major Facilitator Superfamily SQS_PSY PF00494.19 PFH36217.1 - 0.072 12.6 0.2 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Squalene/phytoene synthase Sugar_tr PF00083.24 PFH36217.1 - 5.1 5.8 20.2 0.14 11.0 2.8 3.8 3 2 2 5 5 5 0 Sugar (and other) transporter DUF842 PF05811.13 PFH36218.1 - 1e-24 86.7 12.0 1.2e-24 86.5 12.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF5082 PF16888.5 PFH36218.1 - 0.0077 16.5 0.0 0.06 13.6 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) GRAS PF03514.14 PFH36218.1 - 0.021 13.8 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 GRAS domain family Dcc1 PF09724.9 PFH36219.1 - 1.3e-08 34.6 0.0 0.0002 20.8 0.0 2.4 2 0 0 2 2 2 2 Sister chromatid cohesion protein Dcc1 Ctf8 PF09696.10 PFH36219.1 - 0.014 15.7 0.0 0.094 13.0 0.0 2.0 2 0 0 2 2 2 0 Ctf8 Kinesin PF00225.23 PFH36220.1 - 2.1e-84 283.3 0.0 4.6e-84 282.2 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PFH36220.1 - 4.8e-15 55.8 0.0 9.2e-13 48.4 0.0 3.1 2 1 0 2 2 2 1 Microtubule binding Pkinase PF00069.25 PFH36221.1 - 7.4e-63 212.4 0.0 9.5e-63 212.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36221.1 - 9.7e-38 129.9 0.0 1.2e-37 129.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH36221.1 - 8.9e-06 25.2 0.0 0.00018 21.0 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PFH36221.1 - 0.0012 17.7 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PFH36221.1 - 0.008 16.1 0.1 0.14 12.0 0.4 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PFH36221.1 - 0.15 11.4 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BTK PF00779.19 PFH36222.1 - 0.074 12.9 10.0 0.074 12.9 10.0 3.3 3 1 0 3 3 3 0 BTK motif RIX1 PF08167.12 PFH36222.1 - 0.08 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis FKBP_C PF00254.28 PFH36223.1 - 0.011 16.1 0.1 0.017 15.4 0.1 1.4 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase Laminin_G_3 PF13385.6 PFH36224.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily MMtag PF10159.9 PFH36225.1 - 3e-20 72.3 1.7 5e-20 71.6 1.7 1.4 1 0 0 1 1 1 1 Multiple myeloma tumor-associated Rubis-subs-bind PF09273.11 PFH36226.1 - 3.6e-09 37.4 0.1 1.3e-08 35.5 0.0 2.0 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 PFH36226.1 - 0.00013 22.4 0.0 0.016 15.6 0.0 3.1 2 1 0 2 2 2 1 SET domain CBF PF03914.17 PFH36227.1 - 6.8e-16 58.8 1.0 3.3e-15 56.5 1.0 2.2 1 0 0 1 1 1 1 CBF/Mak21 family RNase_PH PF01138.21 PFH36228.1 - 3.2e-30 105.3 0.2 6.6e-30 104.3 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 DUF5504 PF17608.2 PFH36229.1 - 1.1 9.4 4.0 0.36 11.0 0.9 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5504) Bestrophin PF01062.21 PFH36231.1 - 4.5e-16 59.1 2.7 8.6e-16 58.2 2.7 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Pkinase PF00069.25 PFH36232.1 - 9.1e-28 97.3 0.0 1.8e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36232.1 - 1.5e-11 44.1 0.0 2.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RWD PF05773.22 PFH36232.1 - 1.3e-07 31.9 0.0 4.9e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 RWD domain Acetyltransf_16 PF05301.11 PFH36233.1 - 9.5e-40 136.2 0.1 1.2e-35 122.8 0.0 2.1 2 0 0 2 2 2 2 GNAT acetyltransferase, Mec-17 GFO_IDH_MocA_C PF02894.17 PFH36233.1 - 0.018 15.1 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain PARM PF17061.5 PFH36233.1 - 1.9 8.6 10.0 0.099 12.8 3.9 2.0 2 0 0 2 2 2 0 PARM AAA_12 PF13087.6 PFH36234.1 - 3.2e-34 118.3 0.0 5.6e-23 81.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 PFH36234.1 - 3e-12 46.9 1.6 2e-11 44.2 0.0 3.0 2 1 1 3 3 3 1 AAA domain DUF2439 PF10382.9 PFH36234.1 - 7.1e-07 29.5 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Viral_helicase1 PF01443.18 PFH36234.1 - 0.00047 20.0 0.2 1.6 8.4 0.0 3.3 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 PFH36234.1 - 0.092 13.1 0.1 0.092 13.1 0.1 3.9 4 0 0 4 4 4 0 AAA ATPase domain AAA_22 PF13401.6 PFH36234.1 - 0.16 12.2 0.0 0.45 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 PFH36236.1 - 5.1e-35 118.9 19.1 1.9e-06 28.4 2.3 8.7 8 1 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.8 PFH36236.1 - 1.4e-05 24.0 0.6 0.0084 14.8 0.0 2.7 3 0 0 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PFH36236.1 - 9.9e-05 22.6 0.0 11 6.4 0.0 5.0 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3138 PF11336.8 PFH36236.1 - 0.053 12.1 7.5 0.084 11.5 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Nucleoporin_N PF08801.11 PFH36236.1 - 0.069 11.9 0.0 1.8 7.2 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like Ge1_WD40 PF16529.5 PFH36236.1 - 0.2 10.6 2.3 3.2 6.6 0.1 3.3 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein EGF_3 PF12947.7 PFH36237.1 - 4.7e-05 23.5 9.6 4.7e-05 23.5 9.6 6.6 6 0 0 6 6 6 4 EGF domain UPF0016 PF01169.19 PFH36238.1 - 9e-40 134.9 24.8 1.2e-20 73.6 8.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 PFH36238.1 - 1.2e-05 25.1 6.0 0.00013 21.7 0.6 2.5 2 0 0 2 2 2 2 Putative manganese efflux pump DUF373 PF04123.13 PFH36238.1 - 0.026 14.0 0.8 0.026 14.0 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) EF-hand_7 PF13499.6 PFH36239.1 - 0.0011 19.4 2.3 0.0043 17.5 0.8 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PFH36239.1 - 0.012 15.4 0.1 15 5.9 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 PFH36239.1 - 0.034 13.7 0.5 29 4.5 0.0 3.3 3 0 0 3 3 3 0 EF hand RRM_1 PF00076.22 PFH36240.1 - 2e-25 88.4 0.0 2.1e-15 56.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH36240.1 - 0.0079 16.3 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 PFH36240.1 - 0.23 11.0 0.0 0.4 10.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CECR6_TMEM121 PF14997.6 PFH36244.1 - 4.8e-16 59.2 1.4 8.7e-16 58.3 0.3 2.1 1 1 1 2 2 2 1 CECR6/TMEM121 family VitD-bind_III PF09164.10 PFH36248.1 - 0.46 10.5 2.6 0.48 10.5 0.3 2.3 2 0 0 2 2 2 0 Vitamin D binding protein, domain III SAG PF04092.13 PFH36249.1 - 2.1e-07 31.8 0.0 0.00032 21.5 0.0 2.2 2 0 0 2 2 2 2 SRS domain Syntaxin_2 PF14523.6 PFH36250.1 - 0.062 13.7 2.5 0.59 10.5 0.3 2.8 3 0 0 3 3 3 0 Syntaxin-like protein TipAS PF07739.13 PFH36250.1 - 0.07 13.7 0.0 7.6 7.1 0.0 2.6 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain YtxH PF12732.7 PFH36250.1 - 0.65 10.6 0.0 0.65 10.6 0.0 2.6 3 0 0 3 3 3 0 YtxH-like protein CAP_N PF01213.19 PFH36250.1 - 3.6 7.0 9.0 0.55 9.7 3.4 2.3 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal FAP206 PF12018.8 PFH36252.1 - 1.6e-11 44.3 0.2 0.00062 19.4 0.1 4.0 4 0 0 4 4 4 3 Domain of unknown function YHS PF04945.13 PFH36252.1 - 9.2e-05 22.5 1.7 3.2 7.9 0.2 3.5 3 0 0 3 3 3 3 YHS domain Npa1 PF11707.8 PFH36252.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal SAG PF04092.13 PFH36254.1 - 3.1e-45 154.2 15.4 5.8e-24 85.4 0.4 2.8 2 1 1 3 3 3 2 SRS domain SAG PF04092.13 PFH36255.1 - 3.8e-44 150.7 11.2 3.5e-23 82.8 0.3 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36256.1 - 1.8e-42 145.2 12.3 7.6e-24 85.0 1.3 2.3 2 1 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36257.1 - 3.8e-39 134.5 8.3 5.1e-23 82.3 1.5 2.2 2 0 0 2 2 2 2 SRS domain Gaa1 PF04114.14 PFH36258.1 - 2.2e-24 86.3 0.3 4.1e-19 69.0 0.0 3.6 2 2 0 2 2 2 2 Gaa1-like, GPI transamidase component Pkinase PF00069.25 PFH36261.1 - 1.8e-55 188.1 0.0 1.1e-54 185.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36261.1 - 1e-26 93.8 0.0 4.1e-15 55.8 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 PFH36261.1 - 0.2 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PFH36261.1 - 0.28 10.5 0.0 0.8 9.0 0.0 1.6 2 0 0 2 2 2 0 Kinase-like SF-assemblin PF06705.11 PFH36262.1 - 4.9e-05 22.8 30.1 0.001 18.5 23.0 3.0 1 1 1 2 2 2 2 SF-assemblin/beta giardin Helicase_PWI PF18149.1 PFH36262.1 - 0.012 15.8 1.4 0.012 15.8 1.4 3.2 2 2 1 3 3 3 0 N-terminal helicase PWI domain Baculo_PEP_C PF04513.12 PFH36262.1 - 0.16 12.0 9.2 6.6 6.8 1.5 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 PFH36262.1 - 0.5 10.7 33.9 0.56 10.5 13.5 3.2 1 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Cache_3-Cache_2 PF17201.4 PFH36262.1 - 0.97 8.7 8.4 5 6.3 0.9 2.4 2 0 0 2 2 2 0 Cache 3/Cache 2 fusion domain Rab5-bind PF09311.11 PFH36262.1 - 1.1 8.6 35.9 0.062 12.7 14.4 2.9 1 1 1 2 2 2 0 Rabaptin-like protein ApoLp-III PF07464.11 PFH36262.1 - 3.5 7.7 15.9 1.3 9.1 1.4 2.6 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Tho2 PF11262.8 PFH36262.1 - 7.1 5.7 20.4 0.65 9.1 7.1 2.3 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DeoC PF01791.9 PFH36263.1 - 2.2e-09 37.3 0.1 3e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase FGGY_C PF02782.16 PFH36263.1 - 0.13 12.0 0.1 0.3 10.8 0.1 1.6 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF4708 PF15813.5 PFH36264.1 - 7.8e-05 22.0 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4708) Glycos_transf_2 PF00535.26 PFH36265.1 - 1.1e-26 93.7 0.0 2e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PFH36265.1 - 2.1e-15 57.1 0.5 3.9e-15 56.2 0.5 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 PFH36265.1 - 4.2e-06 26.3 0.0 1.1e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 PFH36265.1 - 3.7e-05 23.7 0.0 6.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 PFH36265.1 - 0.027 13.9 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 NTP_transf_3 PF12804.7 PFH36265.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.6 1 1 0 1 1 1 0 MobA-like NTP transferase domain RicinB_lectin_2 PF14200.6 PFH36265.1 - 0.15 12.8 0.0 0.49 11.2 0.0 1.9 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.9 PFH36265.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Syndecan PF01034.20 PFH36266.1 - 7 6.6 5.4 11 6.0 5.4 1.3 1 0 0 1 1 1 0 Syndecan domain Ala_racemase_N PF01168.20 PFH36267.1 - 1.2e-19 70.8 2.1 1.6e-13 50.8 0.9 3.5 2 1 0 3 3 3 2 Alanine racemase, N-terminal domain ABC_tran PF00005.27 PFH36268.1 - 4.6e-48 163.2 1.3 1.8e-23 83.5 0.1 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 PFH36268.1 - 1.4e-22 79.5 0.4 1.4e-22 79.5 0.4 3.6 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 PFH36268.1 - 6.9e-19 68.8 6.2 1.5e-06 28.2 0.4 4.8 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PFH36268.1 - 1.2e-08 34.7 4.6 0.0056 16.1 0.6 4.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PFH36268.1 - 1.8e-07 31.2 0.6 0.0066 16.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 PFH36268.1 - 4.8e-07 29.4 0.1 0.029 14.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 PFH36268.1 - 7.7e-06 25.8 4.1 0.056 13.1 0.2 3.5 4 0 0 4 4 4 2 AAA ATPase domain MMR_HSR1 PF01926.23 PFH36268.1 - 1.4e-05 25.1 0.0 0.082 13.0 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase MeaB PF03308.16 PFH36268.1 - 0.00016 20.8 0.3 0.21 10.5 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 PFH36268.1 - 0.00017 21.7 0.1 0.49 10.4 0.0 2.8 3 0 0 3 3 2 2 Dynamin family AAA_18 PF13238.6 PFH36268.1 - 0.00017 22.1 1.2 0.093 13.3 0.0 4.1 5 0 0 5 5 5 1 AAA domain AAA_33 PF13671.6 PFH36268.1 - 0.00026 21.2 0.0 0.62 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 PFH36268.1 - 0.00047 20.4 2.1 0.87 9.9 0.4 4.0 4 1 0 4 4 3 1 AAA domain AAA_16 PF13191.6 PFH36268.1 - 0.0012 19.3 4.8 1.5 9.2 0.1 3.7 3 1 0 4 4 3 2 AAA ATPase domain G-alpha PF00503.20 PFH36268.1 - 0.0013 18.0 0.0 0.0035 16.5 0.0 1.7 2 0 0 2 2 2 1 G-protein alpha subunit NB-ARC PF00931.22 PFH36268.1 - 0.0028 16.9 0.1 0.67 9.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Arf PF00025.21 PFH36268.1 - 0.0045 16.5 0.2 0.42 10.1 0.1 2.8 3 0 0 3 3 2 1 ADP-ribosylation factor family NACHT PF05729.12 PFH36268.1 - 0.0055 16.6 0.1 1.6 8.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 PFH36268.1 - 0.0066 16.2 0.0 5.6 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 PFH36268.1 - 0.0084 16.2 2.9 1.1 9.3 0.1 3.5 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_28 PF13521.6 PFH36268.1 - 0.014 15.7 6.8 0.45 10.7 0.0 3.7 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 PFH36268.1 - 0.02 14.8 0.1 3.9 7.4 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.6 PFH36268.1 - 0.021 15.4 13.3 0.47 10.9 0.0 4.2 5 0 0 5 5 3 0 AAA domain Roc PF08477.13 PFH36268.1 - 0.046 13.9 0.1 5.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Phage_int_SAM_2 PF12834.7 PFH36268.1 - 0.053 14.2 0.4 14 6.4 0.1 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal MobB PF03205.14 PFH36268.1 - 0.055 13.4 0.1 5.6 6.9 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 PFH36268.1 - 0.057 13.8 0.0 9.8 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DAP3 PF10236.9 PFH36268.1 - 0.073 12.2 0.8 3.9 6.5 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.6 PFH36268.1 - 0.083 12.5 0.3 15 5.1 0.0 3.4 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.6 PFH36268.1 - 0.083 12.9 0.0 20 5.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain Septin PF00735.18 PFH36268.1 - 0.095 12.0 0.0 4.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.18 PFH36268.1 - 0.096 12.0 0.7 1.6 8.0 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 PFH36268.1 - 0.11 12.9 0.0 24 5.4 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 PFH36268.1 - 0.11 12.1 0.3 0.92 9.1 0.0 2.3 2 1 1 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 PFH36268.1 - 0.12 11.9 0.1 7.8 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF999 PF06198.11 PFH36268.1 - 0.14 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF999) cobW PF02492.19 PFH36268.1 - 0.18 11.4 1.0 19 4.8 0.1 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain FliD_N PF02465.18 PFH36268.1 - 5.3 7.8 6.6 0.72 10.6 0.2 2.9 3 0 0 3 3 1 0 Flagellar hook-associated protein 2 N-terminus eIF-6 PF01912.18 PFH36269.1 - 1.5e-77 259.5 0.2 2.8e-77 258.6 0.2 1.4 2 0 0 2 2 2 1 eIF-6 family RRM_1 PF00076.22 PFH36270.1 - 3.5e-65 215.8 0.0 7e-16 57.8 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PFH36270.1 - 1.1e-11 44.3 0.0 1.6e-08 34.2 0.0 4.3 4 1 1 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 PFH36270.1 - 4.4e-06 27.0 0.0 1.6 8.9 0.0 5.3 6 0 0 6 6 6 2 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 PFH36270.1 - 7.1e-05 22.8 0.4 0.34 11.0 0.1 4.5 4 0 0 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.6 PFH36270.1 - 0.006 16.6 0.0 4.2 7.4 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 PFH36270.1 - 0.028 14.3 0.0 9.2 6.2 0.0 4.0 4 0 0 4 4 4 0 Occluded RNA-recognition motif BRAP2 PF07576.12 PFH36270.1 - 0.032 14.5 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 Smg4_UPF3 PF03467.15 PFH36270.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 0 Smg-4/UPF3 family PDEase_I PF00233.19 PFH36271.1 - 2.5e-68 230.3 0.7 5e-68 229.4 0.0 1.9 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 PFH36271.1 - 0.0086 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 HD domain Phage_holin_3_7 PF05449.11 PFH36271.1 - 0.66 10.0 4.9 0.43 10.6 1.5 2.3 1 1 1 2 2 2 0 Putative 3TM holin, Phage_holin_3 HDV_ag PF01517.18 PFH36271.1 - 0.73 9.6 8.1 4.3 7.1 0.3 2.3 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen PP2C PF00481.21 PFH36272.1 - 8.5e-45 153.4 0.0 1.4e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PFH36272.1 - 1.1e-07 31.7 0.0 3.9e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PFH36272.1 - 8.2e-07 29.1 0.0 0.0011 19.0 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PNTB PF02233.16 PFH36273.1 - 6.4e-145 483.6 13.7 7.8e-145 483.3 5.4 2.1 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 PFH36273.1 - 1.4e-60 204.2 0.2 2.9e-60 203.2 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PNTB_4TM PF12769.7 PFH36273.1 - 1.1e-31 109.1 3.4 1.1e-31 109.1 3.4 3.5 2 1 1 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch AlaDh_PNT_N PF05222.15 PFH36273.1 - 4.9e-31 107.8 0.0 1.5e-30 106.3 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 PFH36273.1 - 3.1e-07 29.9 0.1 0.011 15.1 0.0 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 PFH36273.1 - 0.03 14.0 0.1 0.66 9.7 0.1 2.7 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.14 PFH36273.1 - 0.043 13.0 0.2 0.086 12.1 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA_12 PF13087.6 PFH36275.1 - 4.6e-60 202.7 0.0 7.4e-60 202.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PFH36275.1 - 5.5e-57 193.5 3.9 1.7e-28 100.1 0.5 3.6 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 PFH36275.1 - 9.9e-10 38.5 0.2 3.8e-05 23.5 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 PFH36275.1 - 1.8e-09 38.1 0.1 0.001 19.5 0.1 3.0 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 PFH36275.1 - 3.1e-05 23.8 0.5 0.044 13.5 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 PFH36275.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain UvrD-helicase PF00580.21 PFH36275.1 - 0.0046 16.5 0.0 0.44 10.0 0.1 2.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 PFH36275.1 - 0.0068 15.5 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 PFH36275.1 - 0.014 15.8 0.1 0.04 14.3 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PFH36275.1 - 0.023 15.1 1.0 0.11 12.9 0.0 2.6 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 PFH36275.1 - 0.07 13.4 0.1 0.4 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 PFH36275.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 PFH36275.1 - 0.17 12.4 1.2 0.24 11.9 0.1 1.9 2 0 0 2 2 1 0 AAA domain AP2 PF00847.20 PFH36277.1 - 3.6e-09 36.7 3.9 7.2e-09 35.7 2.5 2.1 2 0 0 2 2 2 1 AP2 domain ACDC PF14733.6 PFH36277.1 - 6.2e-05 23.2 0.8 0.00017 21.9 0.8 1.7 1 1 0 1 1 1 1 AP2-coincident C-terminal DFP PF04127.15 PFH36278.1 - 2.8e-17 63.1 0.0 7.5e-08 32.4 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein ParA PF10609.9 PFH36279.1 - 1.5e-69 234.2 0.0 3.8e-47 160.8 0.0 2.1 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 PFH36279.1 - 2.1e-16 59.8 0.0 4.5e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 PFH36279.1 - 4.9e-11 42.8 0.0 7.4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 PFH36279.1 - 4.9e-09 36.3 0.1 2.5e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.15 PFH36279.1 - 2.2e-05 23.8 0.5 0.07 12.3 0.2 2.4 2 0 0 2 2 2 2 Anion-transporting ATPase DUF971 PF06155.12 PFH36279.1 - 2.4e-05 24.9 0.0 8.9e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF971) MipZ PF09140.11 PFH36279.1 - 6.2e-05 22.4 0.1 0.0002 20.7 0.0 1.8 2 0 0 2 2 2 1 ATPase MipZ CBP_BcsQ PF06564.12 PFH36279.1 - 0.0087 15.6 0.1 0.34 10.4 0.2 2.2 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 PFH36279.1 - 0.039 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CTP_synth_N PF06418.14 PFH36279.1 - 0.04 13.2 0.0 1.9 7.8 0.0 2.7 3 0 0 3 3 3 0 CTP synthase N-terminus VirC1 PF07015.11 PFH36279.1 - 0.05 12.9 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 VirC1 protein Methyltransf_1N PF02870.15 PFH36279.1 - 0.1 13.4 0.0 0.28 12.0 0.0 1.8 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain PGM_PMM_I PF02878.16 PFH36280.1 - 1.3e-34 118.9 0.0 2.6e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 PFH36280.1 - 5e-23 81.7 0.2 1.2e-22 80.5 0.2 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 PFH36280.1 - 8.2e-12 45.3 0.1 1.4e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 PFH36280.1 - 4e-06 26.9 0.0 2.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Got1 PF04178.12 PFH36281.1 - 2.9e-31 108.2 16.9 4e-31 107.7 16.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family CwsA PF10814.8 PFH36281.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA DUF4698 PF15769.5 PFH36281.1 - 3.6 6.6 4.7 4.7 6.2 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) TcpE PF12648.7 PFH36281.1 - 4.7 7.8 15.1 0.84 10.2 1.6 2.2 1 1 1 2 2 2 0 TcpE family BCDHK_Adom3 PF10436.9 PFH36282.1 - 3.8e-31 108.1 0.1 5.3e-31 107.6 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 PFH36282.1 - 6.9e-14 52.3 0.1 7e-13 49.1 0.1 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PFH36282.1 - 0.00093 19.0 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EGF_CA PF07645.15 PFH36284.1 - 4.5e-30 103.6 66.6 1.5e-12 47.5 6.5 6.4 6 0 0 6 6 6 4 Calcium-binding EGF domain cEGF PF12662.7 PFH36284.1 - 6.5e-20 70.7 42.9 3.5e-10 39.6 1.0 7.4 7 0 0 7 7 7 5 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PFH36284.1 - 4.6e-15 55.6 52.8 7.5e-08 32.5 6.2 6.2 6 0 0 6 6 6 4 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 PFH36284.1 - 1.2e-07 31.7 55.2 0.00079 19.6 7.8 5.8 5 0 0 5 5 5 4 EGF domain hEGF PF12661.7 PFH36284.1 - 2.6e-06 27.8 42.4 0.0013 19.3 3.2 6.8 6 1 0 6 6 6 4 Human growth factor-like EGF EGF PF00008.27 PFH36284.1 - 0.00039 20.6 15.1 0.0032 17.7 6.3 6.8 7 1 0 7 7 7 4 EGF-like domain EF-hand_7 PF13499.6 PFH36285.1 - 0.00016 22.0 0.1 0.47 11.0 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 PFH36285.1 - 0.0024 17.7 0.1 3.8 7.7 0.0 3.8 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 PFH36285.1 - 0.12 11.9 0.0 15 5.5 0.0 3.6 3 0 0 3 3 3 0 EF hand DUF4576 PF15144.6 PFH36287.1 - 0.14 12.0 0.1 3.8 7.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) AAA PF00004.29 PFH36288.1 - 1.6e-57 193.6 0.0 7e-40 136.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PFH36288.1 - 2.4e-13 50.8 0.0 1.5e-05 25.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 PFH36288.1 - 1.2e-11 45.0 3.3 0.0031 17.8 0.4 5.0 3 2 1 4 4 4 2 AAA domain AAA_lid_3 PF17862.1 PFH36288.1 - 1.4e-10 40.7 0.1 5e-10 39.0 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 PFH36288.1 - 2e-09 37.8 0.0 0.0022 18.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 PFH36288.1 - 2.2e-08 34.2 0.1 0.0065 16.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PFH36288.1 - 2.4e-08 33.9 0.1 0.002 17.9 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 PFH36288.1 - 2.8e-08 33.4 0.0 0.0056 15.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_2 PF07724.14 PFH36288.1 - 1.7e-07 31.5 0.0 5.5e-05 23.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 PFH36288.1 - 3.1e-07 30.5 0.0 0.043 13.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 PFH36288.1 - 5.4e-07 30.2 0.0 0.023 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 PFH36288.1 - 1.2e-06 27.9 0.1 0.0033 16.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain RNA_helicase PF00910.22 PFH36288.1 - 2.1e-06 28.1 0.0 0.082 13.3 0.0 2.5 2 0 0 2 2 2 2 RNA helicase TsaE PF02367.17 PFH36288.1 - 2.2e-06 27.7 0.0 0.093 12.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 PFH36288.1 - 3.2e-06 26.7 0.3 0.029 13.7 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 PFH36288.1 - 4.4e-06 26.6 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 PFH36288.1 - 4.5e-06 26.7 0.0 0.015 15.2 0.0 3.2 3 0 0 3 3 3 2 NACHT domain IstB_IS21 PF01695.17 PFH36288.1 - 8e-06 25.7 0.0 0.19 11.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 PFH36288.1 - 1.5e-05 24.6 0.0 0.026 14.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 PFH36288.1 - 1.6e-05 24.4 0.0 0.0044 16.4 0.0 2.4 2 0 0 2 2 2 1 KaiC Sigma54_activat PF00158.26 PFH36288.1 - 2.5e-05 24.0 0.0 0.24 11.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 PFH36288.1 - 9.3e-05 22.7 0.0 0.28 11.4 0.0 2.8 3 0 0 3 3 3 2 AAA domain Rad17 PF03215.15 PFH36288.1 - 0.00011 22.1 0.0 0.021 14.8 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain ATPase_2 PF01637.18 PFH36288.1 - 0.00012 22.0 0.3 1.3 8.9 0.0 3.8 2 2 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 PFH36288.1 - 0.00015 21.4 0.3 0.65 9.6 0.0 3.2 2 1 0 3 3 3 2 AAA domain AAA_19 PF13245.6 PFH36288.1 - 0.00023 21.5 0.0 0.53 10.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 PFH36288.1 - 0.00028 20.8 0.0 0.81 9.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 PFH36288.1 - 0.00038 21.0 0.0 0.29 11.7 0.0 2.5 2 0 0 2 2 2 1 ABC transporter TniB PF05621.11 PFH36288.1 - 0.00039 19.9 0.0 1.5 8.2 0.0 3.5 3 0 0 3 3 3 1 Bacterial TniB protein ResIII PF04851.15 PFH36288.1 - 0.00056 20.0 0.0 0.55 10.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 PFH36288.1 - 0.00061 19.1 0.0 0.22 10.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF2075 PF09848.9 PFH36288.1 - 0.00062 19.1 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) CDC48_N PF02359.18 PFH36288.1 - 0.00068 19.8 0.0 0.0025 18.0 0.0 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_17 PF13207.6 PFH36288.1 - 0.00071 20.0 0.0 0.21 12.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 PFH36288.1 - 0.0015 18.4 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 PFH36288.1 - 0.0031 17.0 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.6 PFH36288.1 - 0.0034 17.1 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 PFH36288.1 - 0.0034 17.3 0.0 0.37 10.6 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein Parvo_NS1 PF01057.17 PFH36288.1 - 0.0063 15.6 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DAP3 PF10236.9 PFH36288.1 - 0.013 14.7 0.1 0.59 9.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Viral_helicase1 PF01443.18 PFH36288.1 - 0.014 15.1 0.0 0.28 10.9 0.0 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase SKI PF01202.22 PFH36288.1 - 0.059 13.5 0.1 6.5 6.9 0.0 2.9 3 0 0 3 3 3 0 Shikimate kinase NTPase_1 PF03266.15 PFH36288.1 - 0.06 13.3 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 NTPase KAP_NTPase PF07693.14 PFH36288.1 - 0.098 11.9 0.0 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain DUF815 PF05673.13 PFH36288.1 - 0.11 11.6 0.0 22 4.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) CPT PF07931.12 PFH36288.1 - 0.11 12.3 0.0 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Torsin PF06309.11 PFH36288.1 - 0.12 12.5 0.0 6.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Torsin IPT PF01745.16 PFH36288.1 - 0.13 11.6 0.0 4.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase RNA_Me_trans PF04252.13 PFH36289.1 - 1.2e-53 181.7 0.0 1.7e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase SNF2_N PF00176.23 PFH36290.1 - 4.2e-52 177.0 0.0 3.9e-32 111.3 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 PFH36290.1 - 4.7e-08 32.8 11.2 9.7e-08 31.8 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PFH36290.1 - 8.2e-07 28.8 13.7 1.8e-06 27.7 13.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PFH36290.1 - 1.1e-06 28.4 12.8 2.4e-06 27.3 12.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UBA_4 PF14555.6 PFH36290.1 - 2.1e-06 27.5 0.0 5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Helicase_C PF00271.31 PFH36290.1 - 8.7e-06 26.0 0.0 4.7e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 PFH36290.1 - 1.6e-05 25.2 12.3 4e-05 23.9 12.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PFH36290.1 - 3.6e-05 23.6 10.5 3.6e-05 23.6 10.5 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PFH36290.1 - 0.0019 18.2 8.5 0.0029 17.6 7.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Haem_bd PF14376.6 PFH36290.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Haem-binding domain Prok-RING_4 PF14447.6 PFH36290.1 - 0.016 15.1 11.4 0.038 13.8 11.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PFH36290.1 - 0.02 15.0 12.8 0.045 13.9 12.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PFH36290.1 - 0.24 11.3 4.8 0.52 10.2 4.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 PFH36290.1 - 0.32 11.1 3.8 0.7 10.0 3.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 PFH36290.1 - 0.33 10.8 3.4 0.3 11.0 0.2 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-rbx1 PF12678.7 PFH36290.1 - 1.3 9.4 6.6 3 8.2 6.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 PFH36290.1 - 3 7.7 9.0 0.86 9.5 5.8 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit LisH_2 PF16045.5 PFH36291.1 - 5e-10 38.2 0.1 8e-10 37.6 0.1 1.4 1 0 0 1 1 1 1 LisH FOP_dimer PF09398.10 PFH36291.1 - 9e-08 32.3 0.2 1.7e-07 31.3 0.2 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain AP2 PF00847.20 PFH36292.1 - 0.0017 18.6 3.2 0.003 17.7 3.2 1.4 1 0 0 1 1 1 1 AP2 domain E1-E2_ATPase PF00122.20 PFH36293.1 - 3.2e-11 43.1 0.0 2.7e-10 40.1 0.0 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 PFH36293.1 - 4.5e-11 43.4 0.0 0.0063 16.8 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 PFH36293.1 - 0.00015 21.9 0.3 0.0004 20.5 0.3 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Helicase_C PF00271.31 PFH36294.1 - 7.2e-12 45.6 0.0 2.2e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 PFH36294.1 - 1.5e-11 44.5 0.2 1.5e-11 44.5 0.2 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 PFH36294.1 - 4.9e-06 26.4 0.0 8.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PFH36294.1 - 0.017 15.4 0.1 0.047 14.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 PFH36294.1 - 0.067 13.7 0.0 0.45 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2894 PF11445.8 PFH36294.1 - 0.4 11.1 5.1 0.56 10.7 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Orn_Arg_deC_N PF02784.16 PFH36295.1 - 5.6e-31 107.8 0.0 8.5e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PFH36295.1 - 9.7e-20 70.6 0.0 1.1e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ldh_1_N PF00056.23 PFH36296.1 - 1.3e-40 138.7 0.1 2.2e-40 138.0 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 PFH36296.1 - 5e-30 104.6 0.0 7.6e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 PFH36296.1 - 2e-05 24.2 2.2 0.0015 18.1 0.1 2.6 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase UDPG_MGDP_dh_N PF03721.14 PFH36296.1 - 0.031 13.8 1.3 0.13 11.9 1.3 1.9 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 PFH36296.1 - 0.42 11.2 3.6 1.1 9.9 2.4 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ribosomal_S16 PF00886.19 PFH36297.1 - 2.7e-17 62.6 0.0 6.6e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S16 Cpn60_TCP1 PF00118.24 PFH36298.1 - 1.6e-165 551.4 0.0 1.9e-165 551.3 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Methyltransf_20 PF12147.8 PFH36298.1 - 0.17 11.0 0.1 0.99 8.5 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Piezo_RRas_bdg PF12166.8 PFH36298.1 - 0.18 11.1 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain PAN_1 PF00024.26 PFH36299.1 - 5.8e-19 67.8 17.7 1.9e-07 30.9 2.4 3.4 2 2 1 3 3 3 3 PAN domain PAN_4 PF14295.6 PFH36299.1 - 2.4e-13 49.8 18.6 6.8e-07 29.1 1.4 3.4 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 PFH36300.1 - 1.8e-18 66.2 24.6 1.3e-07 31.5 4.4 3.2 1 1 2 3 3 3 3 PAN domain PAN_4 PF14295.6 PFH36300.1 - 1.5e-10 40.8 20.8 0.0001 22.1 2.3 3.3 3 0 0 3 3 3 3 PAN domain PAN_2 PF08276.11 PFH36300.1 - 0.00066 19.8 1.4 0.00066 19.8 1.4 3.4 3 1 0 3 3 3 2 PAN-like domain PAN_3 PF08277.12 PFH36300.1 - 0.1 12.4 17.8 0.066 13.0 1.8 4.2 3 1 1 4 4 4 0 PAN-like domain PIG-X PF08320.12 PFH36303.1 - 1.4e-10 41.5 0.0 8.5e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 PIG-X / PBN1 PUF PF00806.19 PFH36304.1 - 1.6e-45 150.3 0.0 6.6e-06 25.5 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat MOZ_SAS PF01853.18 PFH36306.1 - 4.2e-73 244.8 0.0 6.3e-73 244.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 PFH36306.1 - 2.6e-22 78.2 1.0 6.2e-22 77.0 1.0 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 PFH36306.1 - 7.2e-11 41.8 0.0 1.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 PFH36306.1 - 0.0018 18.6 0.0 0.0035 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4590 PF15257.6 PFH36306.1 - 0.1 12.5 1.1 0.19 11.7 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) CLP_protease PF00574.23 PFH36307.1 - 2.6e-34 118.7 0.0 4.6e-22 78.8 0.0 3.1 3 0 0 3 3 3 3 Clp protease Transketolase_N PF00456.21 PFH36308.1 - 5e-140 466.2 0.0 7e-140 465.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 PFH36308.1 - 5.7e-30 104.3 0.0 9.8e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PFH36308.1 - 7.6e-11 42.0 0.0 3.9e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 PFH36308.1 - 9.8e-06 25.0 0.0 5.5e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 PFH36308.1 - 0.021 14.6 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 PFH36308.1 - 0.061 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component DUF2280 PF10045.9 PFH36308.1 - 0.21 11.9 0.1 0.44 10.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) Trypsin_2 PF13365.6 PFH36309.1 - 4.6e-18 66.6 0.6 1.3e-17 65.1 0.6 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 PFH36309.1 - 7.7e-11 42.2 0.0 1.6e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PFH36309.1 - 2.1e-10 40.3 0.1 4.3e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PFH36309.1 - 3.1e-05 24.3 0.0 6.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 PFH36309.1 - 0.034 14.1 0.1 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 Tricorn protease PDZ domain SPX PF03105.19 PFH36309.1 - 5.5 6.8 5.2 7.4 6.4 5.2 1.3 1 0 0 1 1 1 0 SPX domain FKBP_C PF00254.28 PFH36310.1 - 2.4e-12 47.0 0.0 4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 PFH36310.1 - 0.0055 17.6 0.0 0.011 16.7 0.0 1.5 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase WD40 PF00400.32 PFH36311.1 - 1.7e-22 79.2 4.8 0.0016 19.2 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH36311.1 - 2.8e-08 33.9 0.0 0.28 11.5 0.0 4.9 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 PFH36311.1 - 2.5e-07 31.0 0.1 3.7e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain RAB3GAP2_N PF14655.6 PFH36311.1 - 0.077 12.2 0.0 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nbas_N PF15492.6 PFH36311.1 - 0.079 12.3 0.1 25 4.1 0.0 3.2 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Corazonin PF17308.2 PFH36311.1 - 0.14 12.5 0.0 0.51 10.7 0.1 1.8 2 0 0 2 2 2 0 Pro-corazonin TTL PF03133.15 PFH36312.1 - 4.7e-50 170.4 0.0 2.9e-48 164.5 0.0 2.8 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PFH36312.1 - 0.00015 21.1 0.0 0.0012 18.2 0.0 2.3 2 1 0 2 2 2 1 YheC/D like ATP-grasp PGK PF00162.19 PFH36313.1 - 1.2e-146 488.6 1.2 1.3e-146 488.4 1.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.11 PFH36313.1 - 0.14 11.7 1.1 2.1 7.9 0.1 2.4 2 0 0 2 2 2 0 Propionate catabolism activator DUF812 PF05667.11 PFH36314.1 - 0.011 14.6 35.3 0.016 14.1 35.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Caldesmon PF02029.15 PFH36314.1 - 1.8 7.3 37.5 2.6 6.7 37.5 1.3 1 0 0 1 1 1 0 Caldesmon DUF934 PF06073.12 PFH36315.1 - 0.01 15.7 0.1 0.026 14.4 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) His_Phos_1 PF00300.22 PFH36316.1 - 2.6e-27 95.8 1.7 7e-24 84.6 0.3 2.7 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Motile_Sperm PF00635.26 PFH36318.1 - 4.9e-23 81.1 0.0 7.1e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain HALZ PF02183.18 PFH36318.1 - 0.02 15.1 1.4 0.041 14.1 1.4 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper ASH PF15780.5 PFH36318.1 - 0.12 12.6 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Ctr PF04145.15 PFH36319.1 - 0.063 13.9 0.1 0.75 10.4 0.0 2.5 3 0 0 3 3 3 0 Ctr copper transporter family Folate_carrier PF01770.18 PFH36319.1 - 0.27 9.9 5.4 0.13 11.0 2.6 1.8 2 0 0 2 2 2 0 Reduced folate carrier DUF2619 PF10942.8 PFH36319.1 - 0.36 10.9 4.0 0.13 12.4 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2619) SART-1 PF03343.13 PFH36320.1 - 2.5e-84 284.1 88.7 9e-66 222.7 80.7 3.0 1 1 1 2 2 2 2 SART-1 family Laminin_N PF00055.17 PFH36322.1 - 0.17 11.4 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Laminin N-terminal (Domain VI) eIF3_p135 PF12807.7 PFH36323.1 - 3.3e-08 33.8 0.0 7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 PFH36323.1 - 0.0065 16.7 0.0 0.0065 16.7 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PFH36323.1 - 0.024 14.7 7.1 6.9 7.1 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 PFH36323.1 - 0.64 10.6 2.9 32 5.1 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat BmKX PF09132.10 PFH36323.1 - 1.2 9.1 3.6 5.4 7.1 3.6 2.1 1 0 0 1 1 1 0 BmKX Pkinase PF00069.25 PFH36324.1 - 1.8e-48 165.2 0.0 2.6e-34 118.8 0.0 4.1 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36324.1 - 3e-21 75.9 0.0 3.1e-19 69.3 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.32 PFH36324.1 - 3e-14 51.4 0.1 0.00055 19.3 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PFH36324.1 - 4.2e-14 51.2 0.5 0.00019 21.1 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 PFH36324.1 - 2.6e-12 45.6 0.4 0.00033 20.0 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 PFH36324.1 - 2.9e-12 46.9 0.4 0.014 15.8 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 PFH36324.1 - 9.5e-05 22.2 0.4 2 8.3 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair Kdo PF06293.14 PFH36324.1 - 0.022 14.1 0.1 0.045 13.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IU_nuc_hydro PF01156.19 PFH36324.1 - 0.073 12.6 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase rRNA_processing PF08524.11 PFH36325.1 - 4.9e-11 42.9 26.5 4.9e-11 42.9 26.5 3.3 2 1 1 3 3 3 1 rRNA processing Pkinase PF00069.25 PFH36326.1 - 2.2e-39 135.4 0.0 5.8e-23 81.6 0.0 3.4 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36326.1 - 7.7e-21 74.5 0.0 1e-13 51.2 0.1 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PFH36326.1 - 0.00032 20.1 0.0 0.72 9.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 PFH36326.1 - 0.01 15.8 0.1 0.03 14.3 0.1 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PFH36326.1 - 0.02 13.7 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Glyoxalase PF00903.25 PFH36327.1 - 9.8e-08 32.3 0.0 1.2e-05 25.5 0.0 3.2 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Nucleo_P87 PF07267.11 PFH36327.1 - 0.08 11.8 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Maf PF02545.14 PFH36329.1 - 1.6e-30 106.1 0.0 1.9e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein AP2 PF00847.20 PFH36330.1 - 1.2e-13 51.1 11.9 7.6e-07 29.3 0.7 2.8 3 0 0 3 3 3 2 AP2 domain CPW_WPC PF09717.10 PFH36331.1 - 2.4e-05 25.2 0.1 6.1e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 Plasmodium falciparum domain of unknown function (CPW_WPC) PITH PF06201.13 PFH36332.1 - 7.1e-24 84.8 0.2 2.8e-23 82.8 0.1 1.9 2 0 0 2 2 2 1 PITH domain RsfS PF02410.15 PFH36334.1 - 2.4e-12 47.1 0.0 4.4e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation ACP_PD PF04336.12 PFH36335.1 - 0.3 11.5 3.1 0.52 10.8 1.4 2.2 2 1 0 2 2 2 0 Acyl carrier protein phosphodiesterase PRKG1_interact PF15898.5 PFH36335.1 - 0.42 11.5 9.9 1.6 9.7 5.1 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Baculo_PEP_C PF04513.12 PFH36335.1 - 0.71 9.9 6.4 0.44 10.6 0.3 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SOSSC PF15925.5 PFH36335.1 - 3 9.2 7.2 1.9 9.8 5.1 1.7 2 0 0 2 2 2 0 SOSS complex subunit C DUF3958 PF13125.6 PFH36335.1 - 3.6 7.8 7.7 2.7 8.2 3.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) Dor1 PF04124.12 PFH36336.1 - 5.6e-22 77.9 0.1 5.5e-12 45.0 0.6 2.1 1 1 1 2 2 2 2 Dor1-like family COX17 PF05051.13 PFH36337.1 - 4.8e-20 71.6 6.4 6.3e-20 71.3 6.4 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) MAPEG PF01124.18 PFH36338.1 - 4.7e-18 65.3 0.8 7e-18 64.8 0.8 1.3 1 0 0 1 1 1 1 MAPEG family PolC_DP2 PF03833.13 PFH36338.1 - 0.33 8.8 0.0 0.41 8.5 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF4131 PF13567.6 PFH36338.1 - 7.7 6.1 7.0 7 6.3 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TP6A_N PF04406.14 PFH36340.1 - 3e-13 49.5 0.2 7e-13 48.4 0.2 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase RNA_pol_Rpb5_C PF01191.19 PFH36341.1 - 9.9e-35 118.3 0.3 2e-34 117.3 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 PFH36341.1 - 1.7e-24 86.2 0.4 3e-24 85.4 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 PFH36341.1 - 6.4e-05 23.0 0.2 0.00016 21.7 0.1 1.8 2 1 0 2 2 2 1 Restriction endonuclease Toprim_3 PF13362.6 PFH36341.1 - 0.093 13.1 0.0 0.54 10.6 0.0 2.1 2 1 0 2 2 2 0 Toprim domain DUF4174 PF13778.6 PFH36341.1 - 0.34 11.4 2.5 1 9.9 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4174) Cpn60_TCP1 PF00118.24 PFH36342.1 - 1.1e-78 265.1 0.5 4.8e-78 263.0 0.5 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4360 PF14273.6 PFH36343.1 - 0.00061 19.7 0.1 0.0023 17.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4360) Pkinase PF00069.25 PFH36344.1 - 3e-27 95.6 0.0 3.7e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36344.1 - 4.4e-17 62.2 0.0 5.4e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PFH36344.1 - 2.2e-09 36.6 0.0 2.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PFH36344.1 - 0.0004 20.4 0.0 0.0007 19.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 PFH36344.1 - 0.014 14.4 0.2 0.024 13.6 0.2 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 PFH36344.1 - 0.048 13.3 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 PFH36344.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Coatomer_WDAD PF04053.14 PFH36345.1 - 8.7e-91 305.2 0.0 2.1e-90 303.9 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 PFH36345.1 - 5.3e-68 229.6 0.0 8.4e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 PFH36345.1 - 1e-43 146.4 9.7 4.7e-07 30.4 0.0 7.0 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH36345.1 - 2.7e-13 50.0 0.0 4.4e-07 30.1 0.0 4.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PFH36345.1 - 0.011 14.5 1.1 0.11 11.2 0.0 2.8 3 1 1 4 4 4 0 Nup133 N terminal like Nup160 PF11715.8 PFH36345.1 - 0.064 11.9 8.1 7.8 5.0 0.1 4.3 3 1 1 4 4 4 0 Nucleoporin Nup120/160 ENTH PF01417.20 PFH36345.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 ENTH domain Efg1 PF10153.9 PFH36346.1 - 1.4e-20 73.7 8.3 1.4e-20 73.7 8.3 1.9 2 0 0 2 2 2 1 rRNA-processing protein Efg1 DUF4194 PF13835.6 PFH36346.1 - 0.052 13.3 3.6 0.93 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4194) Fer2 PF00111.27 PFH36347.1 - 6.3e-12 45.3 1.2 1.1e-11 44.5 1.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RBD PF02196.15 PFH36347.1 - 0.053 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain S-AdoMet_synt_C PF02773.16 PFH36348.1 - 1e-60 203.7 0.0 1.9e-60 202.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 PFH36348.1 - 2e-46 157.1 0.0 4.4e-46 156.0 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 PFH36348.1 - 1.4e-44 150.8 0.5 2.8e-44 149.8 0.5 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain ubiquitin PF00240.23 PFH36349.1 - 9.5e-16 57.3 0.0 1.5e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 PFH36349.1 - 4.2e-08 32.9 0.0 1.2e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Ubiquitin_2 PF14560.6 PFH36349.1 - 0.0014 19.0 0.0 0.0041 17.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain UBA_4 PF14555.6 PFH36349.1 - 0.0093 15.8 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain HOIP-UBA PF16678.5 PFH36349.1 - 0.011 15.8 0.1 0.03 14.3 0.1 1.7 1 0 0 1 1 1 0 HOIP UBA domain pair Rad60-SLD_2 PF13881.6 PFH36349.1 - 0.012 15.8 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 PFH36349.1 - 0.013 15.4 9.4 0.093 12.7 4.3 2.6 1 1 1 2 2 2 0 STI1 domain Rad60-SLD PF11976.8 PFH36349.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.11 PFH36349.1 - 2.6 7.8 14.1 5.9 6.7 9.8 2.9 1 1 1 2 2 2 0 XPC-binding domain EcsC PF12787.7 PFH36350.1 - 0.11 12.1 0.1 0.3 10.7 0.0 1.6 2 0 0 2 2 2 0 EcsC protein family DUF4228 PF14009.6 PFH36350.1 - 2.8 8.3 9.2 0.49 10.8 4.9 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4228) Surp PF01805.20 PFH36351.1 - 3.2e-18 65.4 0.2 8.6e-18 64.1 0.1 1.8 2 0 0 2 2 2 1 Surp module RRM_1 PF00076.22 PFH36351.1 - 9.2e-16 57.4 0.0 2.2e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.12 PFH36351.1 - 1.2e-08 35.0 8.2 1.2e-08 35.0 8.2 2.3 2 0 0 2 2 2 1 cwf21 domain CTK3 PF12243.8 PFH36351.1 - 0.034 14.1 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 RRM_7 PF16367.5 PFH36351.1 - 0.063 13.4 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif Pex14_N PF04695.13 PFH36351.1 - 0.88 10.2 5.2 0.65 10.7 0.8 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5333 PF17267.2 PFH36351.1 - 2.2 8.5 5.3 4.1 7.6 0.6 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5333) CDC37_N PF03234.14 PFH36351.1 - 7.4 7.5 11.5 0.53 11.2 0.3 2.5 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Sec1 PF00995.23 PFH36353.1 - 1.3e-108 364.8 0.0 1.6e-108 364.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF2336 PF10098.9 PFH36353.1 - 0.1 12.0 0.1 0.1 12.0 0.1 2.0 3 0 0 3 3 3 0 Uncharacterised protein conserved in bacteria (DUF2336) FA_hydroxylase PF04116.13 PFH36354.1 - 1.9e-12 47.7 18.1 1.9e-12 47.7 18.1 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.28 PFH36354.1 - 4e-12 46.1 0.0 7.5e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Anth_synt_I_N PF04715.13 PFH36354.1 - 0.012 15.8 0.1 0.024 14.8 0.1 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Dynein_light PF01221.18 PFH36356.1 - 7.9e-26 90.2 0.0 8.8e-26 90.1 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 MORN PF02493.20 PFH36357.1 - 7.1e-18 63.4 32.0 8.2e-06 25.4 2.0 6.2 7 0 0 7 7 7 5 MORN repeat DUF1418 PF07214.12 PFH36358.1 - 0.032 14.1 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) DUF5385 PF17359.2 PFH36358.1 - 0.058 12.9 0.0 0.071 12.7 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF2108 PF09881.9 PFH36359.1 - 0.014 15.3 0.0 0.063 13.3 0.0 2.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2108) DUF4813 PF16072.5 PFH36359.1 - 7.8 6.1 22.7 13 5.3 22.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Abhydrolase_6 PF12697.7 PFH36360.1 - 3.7e-13 50.6 13.8 3.7e-13 50.6 13.8 2.5 2 2 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PFH36360.1 - 3e-10 40.2 0.2 0.0089 15.7 0.0 3.8 4 0 0 4 4 4 3 alpha/beta hydrolase fold PGAP1 PF07819.13 PFH36360.1 - 0.00059 19.6 0.2 0.024 14.4 0.2 2.2 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 PFH36360.1 - 0.0039 16.5 0.1 0.12 11.6 0.2 2.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 PFH36360.1 - 0.0046 16.7 0.6 0.038 13.6 1.5 1.8 2 0 0 2 2 2 1 Putative esterase Lipase_3 PF01764.25 PFH36360.1 - 0.023 14.6 0.5 0.043 13.7 0.5 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.14 PFH36360.1 - 0.3 10.6 0.1 1.5 8.3 0.1 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Cupin_4 PF08007.12 PFH36361.1 - 1.6e-24 87.0 0.0 1.7e-21 77.0 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_8 PF13621.6 PFH36361.1 - 0.0047 16.7 0.0 0.0084 15.9 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 PFH36361.1 - 0.0057 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 PFH36361.1 - 0.091 12.5 0.1 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Cupin domain WD40 PF00400.32 PFH36362.1 - 4.6e-07 30.4 0.3 1.7 9.6 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 PFH36362.1 - 0.044 12.4 0.0 0.11 11.1 0.0 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PFH36362.1 - 0.12 12.6 0.0 7.6 6.9 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Acyltransferase PF01553.21 PFH36363.1 - 8e-20 70.8 0.0 1.2e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Poly_export PF02563.16 PFH36363.1 - 0.077 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein Adaptin_N PF01602.20 PFH36364.1 - 2.8e-149 498.0 13.3 3.9e-149 497.6 13.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 PFH36364.1 - 1.5e-62 210.4 6.7 1.5e-61 207.1 0.2 3.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 PFH36364.1 - 5.1e-20 71.6 0.9 1.4e-19 70.3 0.9 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 PFH36364.1 - 6.9e-17 61.6 12.3 1.4e-08 35.0 0.0 6.4 4 2 2 7 7 7 4 HEAT repeats HEAT PF02985.22 PFH36364.1 - 1.3e-11 43.7 5.6 0.0014 18.8 0.1 6.0 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.23 PFH36364.1 - 1e-06 28.6 4.0 0.04 14.0 0.0 5.5 4 1 1 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 PFH36364.1 - 9.2e-06 25.1 1.3 0.00016 21.0 0.2 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 PFH36364.1 - 3e-05 24.2 3.9 0.66 10.2 0.0 4.8 2 2 2 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 PFH36364.1 - 6.6e-05 22.9 0.7 0.00056 19.8 0.2 2.7 1 1 1 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Alpha_adaptinC2 PF02883.20 PFH36364.1 - 0.00016 21.9 0.0 0.00042 20.6 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_EZ PF13513.6 PFH36364.1 - 0.0025 18.3 4.9 0.66 10.5 0.0 4.5 4 1 1 5 5 4 1 HEAT-like repeat CLASP_N PF12348.8 PFH36364.1 - 0.0075 15.9 7.5 0.46 10.0 0.0 4.1 3 1 1 4 4 4 2 CLASP N terminal Arm_2 PF04826.13 PFH36364.1 - 0.016 14.7 2.2 0.064 12.7 0.0 2.6 2 0 0 2 2 2 0 Armadillo-like RasGEF_N_2 PF14663.6 PFH36364.1 - 0.017 15.5 1.8 0.56 10.6 0.0 3.9 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF5578 PF17741.1 PFH36364.1 - 0.06 12.8 2.4 0.5 9.7 0.1 3.1 2 1 0 2 2 2 0 Family of unknown function (DUF5578) Phage_TAC_12 PF12363.8 PFH36364.1 - 0.79 10.2 3.8 18 5.8 0.3 3.1 3 0 0 3 3 2 0 Phage tail assembly chaperone protein, TAC PFK PF00365.20 PFH36367.1 - 4.4e-57 193.6 0.0 1.1e-34 120.1 0.0 3.3 4 0 0 4 4 4 3 Phosphofructokinase AP2 PF00847.20 PFH36368.1 - 5.5e-11 42.5 5.9 6.8e-06 26.2 1.4 2.9 2 0 0 2 2 2 2 AP2 domain C2 PF00168.30 PFH36369.1 - 1.1e-08 35.3 0.1 1.8e-07 31.4 0.0 3.0 3 0 0 3 3 3 1 C2 domain MoaC PF01967.21 PFH36370.1 - 1.6e-43 148.1 0.2 1.5e-38 132.0 0.0 2.2 2 0 0 2 2 2 2 MoaC family Arf PF00025.21 PFH36371.1 - 1.8e-22 79.6 0.0 9.2e-14 51.3 0.0 3.1 3 0 0 3 3 3 3 ADP-ribosylation factor family G-alpha PF00503.20 PFH36371.1 - 2e-13 50.2 0.0 2e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 PFH36371.1 - 7.4e-08 32.6 0.1 1.6e-05 25.1 0.0 2.6 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 PFH36371.1 - 0.00048 20.3 2.7 2.6 8.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain Ras PF00071.22 PFH36371.1 - 0.0013 18.4 0.0 0.028 14.0 0.0 2.5 3 0 0 3 3 3 1 Ras family Gtr1_RagA PF04670.12 PFH36371.1 - 0.046 13.1 0.0 3.9 6.8 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region NACHT PF05729.12 PFH36371.1 - 0.06 13.3 0.2 0.99 9.3 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Thymidylate_kin PF02223.17 PFH36371.1 - 0.08 12.6 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase GGACT PF06094.12 PFH36372.1 - 1.5e-15 57.8 1.0 5.2e-09 36.8 0.3 2.3 1 1 0 2 2 2 2 Gamma-glutamyl cyclotransferase, AIG2-like Polysacc_synt_C PF14667.6 PFH36376.1 - 0.0029 17.7 5.4 0.0029 17.7 5.4 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain BTB_2 PF02214.22 PFH36377.1 - 2.9e-16 59.6 0.0 4.5e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain CAMSAP_CKK PF08683.11 PFH36379.1 - 5.7e-18 65.2 0.0 9.7e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated DEAD PF00270.29 PFH36380.1 - 1.8e-16 60.4 0.0 1.7e-11 44.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH36380.1 - 0.00064 20.1 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain N2227 PF07942.12 PFH36381.1 - 9.2e-91 303.8 0.0 1.2e-90 303.4 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 PFH36381.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HlyIII PF03006.20 PFH36383.1 - 2e-22 80.0 17.2 2e-22 80.0 17.2 1.4 2 0 0 2 2 2 1 Haemolysin-III related DPM2 PF07297.12 PFH36383.1 - 0.0057 16.9 0.4 0.0057 16.9 0.4 2.9 3 0 0 3 3 3 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) KIAA1430 PF13879.6 PFH36384.1 - 3e-13 50.4 5.2 3e-13 50.4 5.2 2.1 2 1 0 2 2 2 1 KIAA1430 homologue KH_1 PF00013.29 PFH36385.1 - 1.3e-32 111.4 5.0 1.6e-10 40.7 0.6 5.6 5 0 0 5 5 5 5 KH domain KH_2 PF07650.17 PFH36385.1 - 7.4e-05 22.5 0.3 0.63 9.9 0.1 3.1 3 0 0 3 3 3 2 KH domain BMC PF00936.19 PFH36385.1 - 0.0033 17.4 0.1 2.4 8.2 0.0 3.9 4 0 0 4 4 4 2 BMC domain Orai-1 PF07856.12 PFH36386.1 - 0.19 11.4 4.8 0.43 10.2 4.8 1.5 1 0 0 1 1 1 0 Mediator of CRAC channel activity 7TM_GPCR_Str PF10326.9 PFH36388.1 - 0.047 13.0 7.2 0.04 13.3 4.4 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str DUF1482 PF07358.11 PFH36388.1 - 0.16 11.9 0.1 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1482) Pro_isomerase PF00160.21 PFH36389.1 - 5.1e-35 121.1 0.0 1.2e-33 116.6 0.0 2.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MNNL PF07657.13 PFH36389.1 - 0.14 12.2 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 N terminus of Notch ligand CUE PF02845.16 PFH36390.1 - 1.5e-07 31.0 0.0 0.00097 18.8 0.0 2.6 2 0 0 2 2 2 2 CUE domain C2 PF00168.30 PFH36390.1 - 0.00014 22.1 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain UBA_4 PF14555.6 PFH36390.1 - 0.013 15.3 0.2 0.066 13.1 0.1 2.0 2 0 0 2 2 2 0 UBA-like domain Imm7 PF15585.6 PFH36390.1 - 0.14 12.4 0.0 2.5 8.4 0.0 2.3 2 1 0 2 2 2 0 Immunity protein 7 zf-HC5HC2H_2 PF13832.6 PFH36391.1 - 2.4e-06 27.6 42.1 0.0046 17.1 0.1 10.6 11 0 0 11 11 11 4 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PFH36391.1 - 0.15 12.4 0.0 0.15 12.4 0.0 7.5 9 0 0 9 9 9 0 PHD-like zinc-binding domain PIGA PF08288.12 PFH36392.1 - 9.5e-41 138.3 0.2 2e-40 137.2 0.2 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 PFH36392.1 - 1.1e-28 100.3 0.9 1.1e-28 100.3 0.9 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 PFH36392.1 - 3.1e-25 88.7 0.0 5.2e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PFH36392.1 - 7e-23 81.5 0.2 1.3e-22 80.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 PFH36392.1 - 5.5e-17 62.7 0.4 2.7e-16 60.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 PFH36392.1 - 0.00016 21.7 0.1 0.00027 21.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 PFH36392.1 - 0.0024 18.2 0.2 0.0099 16.2 0.2 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 tRNA-synt_1c PF00749.21 PFH36393.1 - 4.6e-54 183.4 0.0 1.2e-41 142.7 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain PDEase_I PF00233.19 PFH36394.1 - 1.4e-69 234.5 0.0 2e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 PFH36394.1 - 0.015 15.5 0.1 0.035 14.3 0.1 1.6 1 0 0 1 1 1 0 HD domain AMMECR1 PF01871.17 PFH36396.1 - 4.2e-40 137.1 0.0 5.6e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 IF2_N PF04760.15 PFH36396.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region GIDA PF01134.22 PFH36397.1 - 2.7e-112 375.7 0.0 2.3e-65 221.2 0.0 3.1 2 1 0 2 2 2 2 Glucose inhibited division protein A GIDA_assoc PF13932.6 PFH36397.1 - 5.3e-38 131.3 0.7 1.2e-20 74.6 0.0 2.3 2 0 0 2 2 2 2 GidA associated domain FAD_oxidored PF12831.7 PFH36397.1 - 2e-07 30.7 1.5 4.6e-07 29.5 1.5 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PFH36397.1 - 8.6e-06 25.2 1.1 1.3e-05 24.6 0.4 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PFH36397.1 - 1e-05 24.8 2.0 1e-05 24.8 2.0 2.1 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 PFH36397.1 - 0.00037 19.9 0.4 0.00074 18.9 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 PFH36397.1 - 0.0012 17.6 1.8 0.002 16.9 0.8 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 PFH36397.1 - 0.0019 18.7 0.4 0.0038 17.7 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PFH36397.1 - 0.044 13.0 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PFH36397.1 - 0.073 12.3 0.3 0.13 11.4 0.3 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 PFH36397.1 - 0.15 12.3 1.8 0.55 10.5 1.8 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_63 PF03200.16 PFH36398.1 - 2e-60 205.0 0.0 2e-36 125.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 PFH36398.1 - 1.1e-05 25.6 0.0 0.00064 19.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Chitin_bind_1 PF00187.19 PFH36398.1 - 0.0071 16.8 8.9 0.016 15.6 8.9 1.6 1 0 0 1 1 1 1 Chitin recognition protein DUF3446 PF11928.8 PFH36398.1 - 3.9 7.9 21.5 0.033 14.5 4.8 3.6 3 0 0 3 3 3 0 Early growth response N-terminal domain COG7 PF10191.9 PFH36399.1 - 0.0007 18.0 1.2 1.1 7.4 0.0 3.0 3 0 0 3 3 3 3 Golgi complex component 7 (COG7) DEAD PF00270.29 PFH36400.1 - 3.8e-09 36.5 0.0 8.7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH36400.1 - 1.5e-08 34.9 0.0 5.5e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain cNMP_binding PF00027.29 PFH36401.1 - 2.1e-44 149.5 0.1 7.2e-22 77.3 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain zf-RING_2 PF13639.6 PFH36402.1 - 2.8e-11 43.5 4.3 5.8e-11 42.6 4.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PFH36402.1 - 1.9e-10 40.4 4.2 3.7e-10 39.5 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PFH36402.1 - 6.3e-10 39.2 1.9 1.3e-09 38.1 1.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PFH36402.1 - 7.1e-09 35.3 2.5 7.1e-09 35.3 2.5 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 PFH36402.1 - 2.4e-07 30.5 3.7 4.8e-07 29.6 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH36402.1 - 1.4e-06 28.1 2.6 2.5e-06 27.4 2.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PFH36402.1 - 1.7e-06 28.0 1.7 3.1e-05 23.9 0.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PFH36402.1 - 1.5e-05 24.7 2.7 2.8e-05 23.9 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PFH36402.1 - 0.00024 21.1 2.6 0.00049 20.1 2.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PFH36402.1 - 0.01 15.7 3.5 0.019 14.8 3.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 PFH36402.1 - 0.054 13.1 4.1 0.12 12.0 4.1 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 PFH36402.1 - 0.072 12.8 3.6 0.17 11.5 3.6 1.6 1 1 0 1 1 1 0 P-11 zinc finger PHD PF00628.29 PFH36402.1 - 0.11 12.5 5.7 0.041 13.8 3.1 1.7 2 0 0 2 2 1 0 PHD-finger RINGv PF12906.7 PFH36402.1 - 0.27 11.4 4.6 0.77 9.9 4.6 1.8 1 0 0 1 1 1 0 RING-variant domain LCCL PF03815.19 PFH36402.1 - 0.37 10.9 2.1 2.4 8.3 0.0 2.2 2 0 0 2 2 2 0 LCCL domain zf-RING_4 PF14570.6 PFH36402.1 - 0.59 10.0 3.8 0.63 9.9 2.6 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 PFH36402.1 - 0.71 10.0 5.9 0.39 10.8 3.4 2.0 2 0 0 2 2 2 0 Zinc-finger zf-RING-like PF08746.11 PFH36402.1 - 1.2 9.5 5.2 1.4 9.3 2.3 2.2 2 0 0 2 2 2 0 RING-like domain Zf_RING PF16744.5 PFH36402.1 - 7 6.8 5.8 18 5.5 2.4 2.6 2 1 1 3 3 3 0 KIAA1045 RING finger V-SNARE_C PF12352.8 PFH36403.1 - 7.5e-09 35.7 1.9 1.5e-08 34.8 1.9 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 PFH36403.1 - 0.019 15.3 0.1 0.038 14.4 0.1 1.5 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus EOS1 PF12326.8 PFH36403.1 - 0.034 14.1 2.1 0.071 13.0 2.1 1.4 1 0 0 1 1 1 0 N-glycosylation protein zf-CCCH PF00642.24 PFH36404.1 - 6.2e-12 45.1 21.1 0.0001 22.1 0.8 4.0 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 PFH36404.1 - 8.9e-07 29.1 10.0 0.0042 17.3 4.1 2.6 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 PFH36404.1 - 1.8e-06 27.6 21.0 0.00029 20.6 2.8 4.0 3 1 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 PFH36404.1 - 5.6e-06 27.0 12.2 0.066 13.9 0.0 3.4 1 1 2 3 3 3 3 Torus domain zf_CCCH_4 PF18345.1 PFH36404.1 - 0.00028 20.8 30.3 0.25 11.5 8.0 4.5 4 1 0 4 4 4 3 Zinc finger domain zf-CCCH_2 PF14608.6 PFH36404.1 - 0.021 15.3 0.9 0.021 15.3 0.9 3.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 PFH36404.1 - 4.2 7.2 13.7 0.11 12.2 1.7 2.9 3 0 0 3 3 3 0 Putative zinc-finger domain Pkinase PF00069.25 PFH36405.1 - 1.6e-24 86.7 0.0 3.8e-24 85.5 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 PFH36405.1 - 1.4e-19 70.6 0.0 2e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH36405.1 - 5.2e-15 55.4 0.0 9.6e-15 54.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH36405.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PFH36405.1 - 0.053 12.5 0.0 0.077 11.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 PFH36405.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase NUDIX PF00293.28 PFH36407.1 - 5.3e-08 33.0 1.2 2.5e-05 24.3 0.8 2.3 2 0 0 2 2 2 2 NUDIX domain Proteasome PF00227.26 PFH36408.1 - 8.4e-37 126.5 0.6 1.3e-36 125.9 0.6 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PFH36408.1 - 5.5e-15 54.7 0.0 1.1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DHDPS PF00701.22 PFH36409.1 - 3.7e-86 288.4 0.0 4.2e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 PFH36409.1 - 0.05 13.6 0.2 0.12 12.4 0.2 1.6 1 0 0 1 1 1 0 PA domain zf-B_box PF00643.24 PFH36410.1 - 3.2e-10 40.0 11.6 2e-05 24.6 0.7 2.3 2 0 0 2 2 2 2 B-box zinc finger CEBP_ZZ PF16366.5 PFH36410.1 - 4.5 7.6 7.9 0.76 10.1 0.2 2.5 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Ribosomal_S7 PF00177.21 PFH36411.1 - 2.4e-38 131.1 1.4 2.8e-38 130.9 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S14 PF00253.21 PFH36412.1 - 1.3e-11 44.1 6.2 1.8e-11 43.6 6.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e TPR_19 PF14559.6 PFH36413.1 - 7e-28 96.9 41.4 4.3e-05 23.9 0.2 12.4 9 4 3 13 13 12 8 Tetratricopeptide repeat TPR_16 PF13432.6 PFH36413.1 - 6.3e-20 71.5 37.9 2.6e-05 24.8 1.6 9.7 7 2 2 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 PFH36413.1 - 3e-16 58.1 39.5 0.023 14.8 1.5 14.0 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_14 PF13428.6 PFH36413.1 - 8.1e-15 54.3 64.2 0.00084 20.0 1.0 16.4 12 4 7 20 20 16 5 Tetratricopeptide repeat TPR_8 PF13181.6 PFH36413.1 - 8.3e-11 41.2 15.8 0.53 10.6 0.1 10.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 PFH36413.1 - 1.2e-10 40.7 17.3 0.19 11.6 0.4 11.4 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_12 PF13424.6 PFH36413.1 - 3.6e-08 33.6 38.8 0.072 13.4 3.5 9.9 9 2 0 9 9 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH36413.1 - 1.6e-06 28.2 23.6 0.011 15.9 0.2 8.0 8 2 1 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PFH36413.1 - 0.00093 19.1 28.4 0.099 12.7 0.3 9.5 10 0 0 10 10 10 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PFH36413.1 - 0.0016 18.5 3.6 5.7 7.1 0.1 4.8 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat HrpB1_HrpK PF09613.10 PFH36413.1 - 0.016 14.9 20.5 1.6 8.3 0.3 6.7 8 0 0 8 8 8 0 Bacterial type III secretion protein (HrpB1_HrpK) ChAPs PF09295.10 PFH36413.1 - 0.11 11.5 0.0 1.9 7.4 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_17 PF13431.6 PFH36413.1 - 0.22 12.0 6.2 18 6.0 0.0 6.4 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 PFH36413.1 - 0.31 11.2 45.9 0.034 14.3 2.4 8.8 9 1 1 10 10 9 0 Tetratricopeptide repeat DDT PF02791.17 PFH36413.1 - 0.67 10.3 6.3 6.7 7.1 0.1 3.5 3 0 0 3 3 3 0 DDT domain TPR_4 PF07721.14 PFH36413.1 - 1.8 9.4 29.2 2.8 8.8 0.5 9.3 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_20 PF14561.6 PFH36413.1 - 5.1 7.5 19.6 16 6.0 0.0 7.3 6 2 1 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH36413.1 - 10 7.0 23.0 46 4.9 0.1 9.6 12 0 0 12 12 10 0 Tetratricopeptide repeat DUF4200 PF13863.6 PFH36414.1 - 1.3e-06 28.8 7.6 1.3e-06 28.8 7.6 3.9 5 0 0 5 5 5 1 Domain of unknown function (DUF4200) Herpes_UL33 PF03581.13 PFH36414.1 - 0.083 13.3 0.3 0.5 10.8 0.3 2.4 1 0 0 1 1 1 0 Herpesvirus UL33-like protein DUF1664 PF07889.12 PFH36414.1 - 3.5 7.7 9.4 7.9 6.5 0.2 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ELO PF01151.18 PFH36415.1 - 8.7e-44 149.9 27.5 1.3e-43 149.3 27.5 1.3 1 1 0 1 1 1 1 GNS1/SUR4 family ECH_1 PF00378.20 PFH36416.1 - 4.6e-23 81.8 0.0 5.8e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PFH36416.1 - 3.6e-12 46.4 0.1 4.4e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pkinase PF00069.25 PFH36417.1 - 3.1e-79 266.1 0.0 5.1e-79 265.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36417.1 - 6.3e-35 120.7 0.0 9.8e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 PFH36417.1 - 4.5e-28 94.7 8.0 2e-07 30.0 2.2 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PFH36417.1 - 2.4e-23 82.4 0.3 3.5e-10 40.2 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH36417.1 - 9.1e-23 78.2 3.7 5.6e-05 22.8 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PFH36417.1 - 2.2e-19 68.0 10.6 6.6e-05 22.2 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 PFH36417.1 - 2.8e-18 65.5 7.1 6.5e-05 22.7 0.9 4.5 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 PFH36417.1 - 6e-06 26.5 0.2 1 9.7 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain Kinase-like PF14531.6 PFH36417.1 - 0.00026 20.4 0.0 0.00049 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like EF-hand_4 PF12763.7 PFH36417.1 - 0.00032 20.6 0.5 1.1 9.2 0.0 3.1 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 PFH36417.1 - 0.0026 17.2 0.0 0.0071 15.7 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.9 PFH36417.1 - 0.0057 17.0 0.0 3.5 8.0 0.0 3.2 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Pkinase_fungal PF17667.1 PFH36417.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Toprim_2 PF13155.6 PFH36417.1 - 0.016 15.6 0.9 0.82 10.1 0.0 3.0 1 1 1 3 3 3 0 Toprim-like EF-hand_14 PF17959.1 PFH36417.1 - 0.02 15.2 0.0 0.36 11.2 0.0 2.9 2 1 1 3 3 2 0 EF-hand domain APH PF01636.23 PFH36417.1 - 0.021 14.8 0.0 0.096 12.6 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Amino_oxidase PF01593.24 PFH36418.1 - 5.6e-38 131.4 1.5 7.4e-28 98.0 0.0 3.5 4 0 0 4 4 4 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PFH36418.1 - 8e-12 45.2 0.1 2.8e-11 43.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 PFH36418.1 - 3.6e-07 29.9 0.0 8.1e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PFH36418.1 - 1.2e-05 24.6 1.3 1.2e-05 24.6 1.3 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 PFH36418.1 - 1.7e-05 24.2 0.0 3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PFH36418.1 - 1.9e-05 24.4 0.0 5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 PFH36418.1 - 0.00014 22.3 0.1 0.00029 21.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PFH36418.1 - 0.00056 19.2 0.1 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 PFH36418.1 - 0.00076 18.7 0.7 0.0013 17.9 0.7 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A PHD PF00628.29 PFH36418.1 - 0.00096 19.0 0.3 0.0033 17.3 0.3 2.0 1 0 0 1 1 1 1 PHD-finger HI0933_like PF03486.14 PFH36418.1 - 0.0017 17.1 0.3 0.0025 16.6 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 PFH36418.1 - 0.0027 17.0 0.1 0.005 16.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 PFH36418.1 - 0.0087 15.3 0.3 0.019 14.2 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 PFH36418.1 - 0.11 11.5 0.4 0.19 10.7 0.4 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Mito_carr PF00153.27 PFH36420.1 - 8.7e-44 147.4 13.8 7.3e-21 73.9 0.1 5.4 5 1 0 5 5 5 4 Mitochondrial carrier protein Fe_hyd_lg_C PF02906.14 PFH36422.1 - 3.2e-43 148.1 0.0 4.8e-15 55.9 0.0 4.3 4 0 0 4 4 4 4 Iron only hydrogenase large subunit, C-terminal domain Metal_resist PF13801.6 PFH36423.1 - 0.071 13.3 1.8 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 Heavy-metal resistance 6PGD PF00393.19 PFH36424.1 - 2.2e-106 355.5 0.0 2.9e-106 355.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 PFH36424.1 - 7.2e-32 110.7 0.0 1.1e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 PFH36424.1 - 0.002 18.0 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 PFH36424.1 - 0.053 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase WD40 PF00400.32 PFH36425.1 - 2.5e-09 37.6 13.2 0.003 18.4 0.8 6.3 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH36425.1 - 0.028 14.7 0.1 35 4.8 0.0 3.3 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain AAA_5 PF07728.14 PFH36426.1 - 4.9e-104 344.0 0.0 8.5e-20 71.2 0.0 10.0 10 0 0 10 10 10 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 PFH36426.1 - 5.5e-26 90.8 8.1 3.9e-13 49.5 0.1 5.9 5 0 0 5 5 5 3 Midasin AAA lid domain AAA_16 PF13191.6 PFH36426.1 - 6.8e-23 81.9 15.3 0.0047 17.3 0.0 9.2 8 0 0 8 8 6 5 AAA ATPase domain AAA PF00004.29 PFH36426.1 - 3.7e-21 75.9 0.0 0.012 16.1 0.0 7.0 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 PFH36426.1 - 1.1e-18 67.5 0.0 0.00041 20.4 0.0 6.6 6 0 0 6 6 6 3 Dynein heavy chain region D6 P-loop domain AAA_lid_5 PF17865.1 PFH36426.1 - 5.4e-18 65.0 0.0 1.5e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_22 PF13401.6 PFH36426.1 - 4.5e-16 59.4 0.0 0.13 12.5 0.0 7.6 6 0 0 6 6 6 4 AAA domain AAA_3 PF07726.11 PFH36426.1 - 3.3e-15 56.1 0.0 0.00021 21.1 0.0 7.4 8 0 0 8 8 7 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PFH36426.1 - 6.1e-15 55.2 0.0 0.0078 15.7 0.0 6.2 6 0 0 6 6 6 3 P-loop containing dynein motor region Mg_chelatase PF01078.21 PFH36426.1 - 5.8e-13 48.7 1.2 0.0076 15.7 0.0 7.2 7 1 1 8 8 8 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 PFH36426.1 - 6.4e-11 42.3 0.2 0.068 12.9 0.0 7.5 7 0 0 7 7 6 1 AAA domain TsaE PF02367.17 PFH36426.1 - 3.1e-10 40.1 0.2 0.52 10.3 0.0 5.5 5 0 0 5 5 5 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 PFH36426.1 - 2.5e-09 37.3 3.1 0.065 13.1 0.0 5.2 5 0 0 5 5 4 2 NACHT domain AAA_33 PF13671.6 PFH36426.1 - 5.2e-08 33.2 0.0 1.1 9.4 0.0 5.9 5 0 0 5 5 5 1 AAA domain ABC_tran PF00005.27 PFH36426.1 - 2.4e-07 31.3 0.1 2.1 8.9 0.0 6.3 6 0 0 6 6 6 1 ABC transporter AAA_18 PF13238.6 PFH36426.1 - 4.2e-07 30.6 0.2 24 5.5 0.0 6.4 6 0 0 6 6 6 0 AAA domain AAA_6 PF12774.7 PFH36426.1 - 7.7e-07 28.4 0.0 0.05 12.6 0.0 5.4 5 0 0 5 5 5 1 Hydrolytic ATP binding site of dynein motor region AAA_29 PF13555.6 PFH36426.1 - 3e-06 26.9 0.9 15 5.4 0.0 6.3 6 0 0 6 6 6 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 PFH36426.1 - 3.2e-06 26.6 0.1 1.9 7.7 0.0 5.6 6 0 0 6 6 6 1 Zeta toxin RuvB_N PF05496.12 PFH36426.1 - 1.2e-05 25.1 0.0 0.55 10.0 0.0 5.8 7 0 0 7 7 7 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 PFH36426.1 - 5.2e-05 23.2 0.2 2.5 8.0 0.0 5.5 6 0 0 6 6 6 1 Rad17 P-loop domain AAA_19 PF13245.6 PFH36426.1 - 0.00011 22.5 0.7 10 6.4 0.0 5.3 5 0 0 5 5 4 0 AAA domain VWA PF00092.28 PFH36426.1 - 0.00026 21.3 0.0 0.00054 20.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_25 PF13481.6 PFH36426.1 - 0.00029 20.5 3.3 2.4 7.7 0.1 5.5 6 0 0 6 6 5 1 AAA domain RNA_helicase PF00910.22 PFH36426.1 - 0.001 19.4 0.4 27 5.2 0.0 5.1 6 0 0 6 6 5 0 RNA helicase T2SSE PF00437.20 PFH36426.1 - 0.0073 15.4 0.2 1.4 7.9 0.0 4.2 6 0 0 6 6 5 1 Type II/IV secretion system protein DUF815 PF05673.13 PFH36426.1 - 0.011 14.9 0.1 1.8 7.7 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) MCM PF00493.23 PFH36426.1 - 0.041 13.0 0.0 9.8 5.2 0.0 3.3 4 0 0 4 4 4 0 MCM P-loop domain TniB PF05621.11 PFH36426.1 - 0.063 12.7 0.0 46 3.3 0.0 4.1 5 0 0 5 5 5 0 Bacterial TniB protein TIP49 PF06068.13 PFH36426.1 - 0.11 11.7 1.0 6.5 5.8 0.0 3.5 5 0 0 5 5 3 0 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 PFH36426.1 - 0.12 12.5 0.8 15 5.7 0.0 4.2 6 0 0 6 6 4 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 PFH36426.1 - 0.14 11.9 0.0 12 5.5 0.0 3.9 5 0 0 5 5 4 0 Viral (Superfamily 1) RNA helicase PIG-Y PF15159.6 PFH36428.1 - 1.9e-16 60.8 0.0 3e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Vps35 PF03635.17 PFH36429.1 - 9.7e-263 874.0 0.0 1.1e-262 873.8 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DDT PF02791.17 PFH36429.1 - 0.035 14.4 4.8 5.4 7.4 0.2 4.5 4 0 0 4 4 4 0 DDT domain DUF758 PF05527.11 PFH36429.1 - 0.25 11.3 5.3 0.11 12.5 1.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF758) Aminopep PF10023.9 PFH36429.1 - 0.72 9.2 3.7 1.1 8.6 0.1 2.5 3 0 0 3 3 3 0 Putative aminopeptidase Ribosomal_L24e PF01246.20 PFH36431.1 - 1.5e-32 111.6 5.1 3.5e-32 110.4 5.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e HTH_19 PF12844.7 PFH36431.1 - 0.0047 16.9 4.9 0.0094 16.0 4.9 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Slu7 PF11708.8 PFH36431.1 - 0.023 14.5 12.2 0.032 14.0 12.2 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor zf-FCS PF06467.14 PFH36431.1 - 0.028 14.3 3.3 0.055 13.4 3.1 1.6 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif PBP1_TM PF14812.6 PFH36431.1 - 1.1 9.6 12.9 0.29 11.5 4.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Asp PF00026.23 PFH36433.1 - 3.6e-22 79.2 0.0 2.2e-14 53.6 0.0 2.7 2 2 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 PFH36433.1 - 1.5e-20 73.6 0.0 2.7e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 PFH36433.1 - 6.4e-19 68.9 1.5 1.1e-18 68.0 0.4 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Guanylate_kin PF00625.21 PFH36434.1 - 4.1e-54 183.0 0.0 6.4e-54 182.4 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 PFH36434.1 - 0.00018 21.9 0.2 0.00018 21.9 0.2 2.3 1 1 1 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 PFH36434.1 - 0.00019 21.4 0.0 0.00064 19.7 0.0 1.8 2 1 1 3 3 3 1 RsgA GTPase NB-ARC PF00931.22 PFH36434.1 - 0.0063 15.7 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 PFH36434.1 - 0.0074 16.4 0.4 0.032 14.4 0.4 2.0 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 PFH36434.1 - 0.0097 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 PFH36434.1 - 0.02 15.4 0.0 0.067 13.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PFH36434.1 - 0.024 14.9 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PFH36434.1 - 0.028 14.9 0.1 0.06 13.9 0.1 1.8 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 PFH36434.1 - 0.028 14.3 0.1 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 PFH36434.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.18 PFH36434.1 - 0.15 11.3 0.0 0.54 9.5 0.0 1.8 2 0 0 2 2 2 0 Septin DUF1493 PF07377.12 PFH36434.1 - 0.16 12.5 0.1 0.26 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4855 PF16147.5 PFH36438.1 - 0.11 11.6 0.1 0.22 10.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) DUF3037 PF11236.8 PFH36438.1 - 2.6 8.5 7.0 0.75 10.2 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) zf-C4H2 PF10146.9 PFH36438.1 - 9.2 6.5 8.0 5.2 7.3 0.2 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein Sec10 PF07393.11 PFH36440.1 - 5.4 5.3 7.1 9.3 4.5 7.1 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec10 Csm1_N PF18504.1 PFH36441.1 - 0.0014 18.9 2.5 0.0014 18.9 2.5 20.1 11 5 13 25 25 25 3 Csm1 N-terminal domain ADIP PF11559.8 PFH36441.1 - 0.0056 16.8 13.8 0.0056 16.8 13.8 14.8 3 3 12 16 16 16 3 Afadin- and alpha -actinin-Binding Ribosomal_S8e PF01201.22 PFH36442.1 - 4e-49 166.3 5.1 4e-49 166.3 5.1 1.9 1 1 1 2 2 2 1 Ribosomal protein S8e CASP_C PF08172.12 PFH36442.1 - 0.12 11.7 4.7 0.17 11.2 4.7 1.2 1 0 0 1 1 1 0 CASP C terminal DUF3246 PF11596.8 PFH36444.1 - 0.046 13.1 2.8 0.17 11.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Bacteriocin_IId PF09221.10 PFH36444.1 - 0.28 11.4 2.6 7.2 6.9 0.6 2.3 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like DUF3245 PF11595.8 PFH36444.1 - 2.5 8.6 16.7 0.43 11.1 2.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3245) FAM176 PF14851.6 PFH36444.1 - 3.8 7.2 9.3 1.3 8.6 0.4 2.2 2 0 0 2 2 2 0 FAM176 family XRN_N PF03159.18 PFH36445.1 - 3.4e-88 295.2 0.0 5.5e-88 294.5 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PFH36445.1 - 1.3e-61 208.9 2.1 1.3e-46 159.5 0.2 2.2 1 1 1 2 2 2 2 Xrn1 helical domain SH3_12 PF18129.1 PFH36445.1 - 1.7e-10 40.8 2.7 4.7e-10 39.4 2.7 1.7 1 1 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D1 PF18332.1 PFH36445.1 - 0.0066 16.2 0.0 0.027 14.3 0.0 1.8 1 1 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain KASH_CCD PF14662.6 PFH36448.1 - 1.5e-06 28.1 78.3 0.0093 15.8 23.1 4.4 2 1 2 4 4 4 3 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 PFH36448.1 - 0.00036 20.6 18.0 0.00036 20.6 18.0 5.6 2 2 3 5 5 5 4 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 PFH36448.1 - 0.0032 17.7 34.2 0.0032 17.7 34.2 4.2 1 1 3 4 4 3 2 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 PFH36448.1 - 0.04 14.2 0.6 0.04 14.2 0.6 6.2 2 1 4 6 6 6 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 PFH36448.1 - 0.1 13.1 93.5 0.27 11.7 6.8 8.1 2 1 6 8 8 8 0 Cell division protein ZapB APG6_N PF17675.1 PFH36448.1 - 0.11 13.0 89.5 0.11 13.0 16.5 5.8 2 1 4 6 6 5 0 Apg6 coiled-coil region Leu_zip PF15294.6 PFH36448.1 - 0.11 12.0 68.1 0.04 13.5 12.2 4.4 1 1 3 4 4 4 0 Leucine zipper Spc7 PF08317.11 PFH36448.1 - 0.19 10.6 78.9 0.011 14.6 22.5 4.9 2 1 3 5 5 5 0 Spc7 kinetochore protein ERM PF00769.19 PFH36448.1 - 1.3 8.8 88.7 2.6 7.8 1.9 4.3 2 1 2 4 4 4 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 PFH36448.1 - 3.5 7.7 47.8 0.083 12.9 4.2 5.9 2 1 4 6 6 6 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 PFH36448.1 - 3.7 8.0 72.4 0.021 15.3 21.1 3.8 2 1 2 4 4 4 0 Fez1 ADIP PF11559.8 PFH36448.1 - 8.9 6.4 85.0 0.42 10.7 9.9 5.5 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding SET PF00856.28 PFH36449.1 - 2.7e-08 34.4 0.0 0.0018 18.7 0.0 2.5 2 1 0 2 2 2 2 SET domain Flavoprotein PF02441.19 PFH36450.1 - 2.8e-49 166.9 0.0 3.4e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein BLM10_mid PF16507.5 PFH36451.1 - 1.5e-39 136.1 0.0 1.3e-21 76.9 0.0 4.1 4 0 0 4 4 4 4 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 PFH36451.1 - 2.1e-26 91.7 0.0 7e-26 90.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) DUF1244 PF06844.11 PFH36451.1 - 0.13 12.4 0.1 0.35 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) DUF4611 PF15387.6 PFH36451.1 - 0.68 10.2 3.2 7.7 6.8 0.9 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) HEAT PF02985.22 PFH36451.1 - 1.5 9.3 10.6 0.68 10.4 0.1 5.2 6 0 0 6 6 6 0 HEAT repeat DUF4685 PF15737.5 PFH36452.1 - 0.095 13.1 19.6 0.018 15.5 7.1 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) Peptidase_C97 PF05903.14 PFH36453.1 - 2e-23 82.9 0.0 2.9e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain WD40 PF00400.32 PFH36454.1 - 2.9e-16 59.6 9.3 0.0037 18.1 0.0 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH36454.1 - 9e-12 45.1 0.1 0.026 14.8 0.0 5.2 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PFH36454.1 - 0.00027 20.0 1.8 0.57 9.1 0.0 4.1 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 PFH36454.1 - 0.0036 16.9 0.3 0.0093 15.6 0.3 1.7 1 1 0 1 1 1 1 PQQ-like domain Nbas_N PF15492.6 PFH36454.1 - 0.12 11.7 0.1 5.8 6.2 0.0 2.8 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Myosin_head PF00063.21 PFH36455.1 - 4.7e-191 636.5 3.4 7.6e-191 635.8 3.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) RCC1 PF00415.18 PFH36455.1 - 5.7e-32 110.1 14.4 1.5e-09 38.3 0.1 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH36455.1 - 1.7e-29 100.9 22.0 7.8e-12 44.7 0.2 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 PFH36455.1 - 8.3e-21 71.8 44.4 0.00027 20.5 0.1 8.7 8 0 0 8 8 8 6 IQ calmodulin-binding motif Myosin_N PF02736.19 PFH36455.1 - 0.00078 19.2 0.2 0.002 17.9 0.2 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 PFH36455.1 - 0.0042 17.5 0.0 0.017 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PFH36455.1 - 0.03 14.6 0.1 0.1 12.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PFH36455.1 - 0.091 12.5 0.1 0.29 10.8 0.1 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain CbiA PF01656.23 PFH36455.1 - 0.14 12.2 0.2 0.35 10.9 0.2 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain BRCA2 PF00634.18 PFH36456.1 - 5.8e-19 67.5 50.2 12 5.7 0.1 16.5 16 0 0 16 16 16 16 BRCA2 repeat EKR PF10371.9 PFH36456.1 - 2e-13 49.9 10.1 1.8 8.4 0.0 14.8 16 0 0 16 16 16 1 Domain of unknown function BRCA-2_OB1 PF09103.10 PFH36456.1 - 5.4e-07 29.6 0.0 2.9e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Met_10 PF02475.16 PFH36457.1 - 1.8e-45 155.2 0.0 3e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 PFH36457.1 - 1.6e-05 24.2 0.0 2.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.14 PFH36457.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 PFH36457.1 - 0.023 14.4 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PrmA PF06325.13 PFH36457.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DNA_methylase PF00145.17 PFH36457.1 - 0.16 11.3 0.8 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase Orf78 PF06024.12 PFH36458.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) DUF4519 PF15012.6 PFH36458.1 - 0.19 11.9 0.4 0.43 10.8 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Peptidase_C14 PF00656.22 PFH36459.1 - 7.3e-14 52.3 0.0 1.4e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Caspase domain EspB_PE PF18625.1 PFH36459.1 - 2.4 8.7 8.3 0.58 10.7 0.3 3.6 2 1 0 2 2 2 0 ESX-1 secreted protein B PE domain DUF4604 PF15377.6 PFH36460.1 - 0.0017 18.8 2.1 0.0017 18.8 2.1 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4604) Pkinase PF00069.25 PFH36462.1 - 6.2e-37 127.4 0.0 2.7e-19 69.5 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36462.1 - 1.1e-07 31.5 0.0 0.00086 18.7 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PFH36462.1 - 0.00015 21.2 0.0 0.079 12.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 PFH36462.1 - 0.041 13.5 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PFH36462.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_C26 PF07722.13 PFH36463.1 - 4.5e-14 52.7 0.0 1.3e-11 44.7 0.0 2.6 2 0 0 2 2 2 2 Peptidase C26 GATase PF00117.28 PFH36463.1 - 1.6e-08 34.6 0.0 0.0093 15.7 0.0 2.6 3 0 0 3 3 3 2 Glutamine amidotransferase class-I DUF2012 PF09430.10 PFH36466.1 - 7.9e-08 32.5 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) PX PF00787.24 PFH36467.1 - 1.1e-05 25.4 0.8 8.9e-05 22.4 0.8 2.1 1 1 0 1 1 1 1 PX domain Phage_fiber_2 PF03406.13 PFH36467.1 - 0.068 12.7 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 Phage tail fibre repeat Acetyltransf_6 PF13480.7 PFH36467.1 - 0.54 10.4 3.2 3.8 7.7 1.1 2.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain EamA PF00892.20 PFH36469.1 - 4 7.6 15.7 0.61 10.2 10.4 2.1 2 0 0 2 2 2 0 EamA-like transporter family TPR_2 PF07719.17 PFH36470.1 - 2.3e-07 30.4 1.4 0.07 13.3 0.0 4.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PFH36470.1 - 2.8e-07 30.1 0.0 0.016 15.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PFH36470.1 - 3.1e-07 30.9 0.6 5.1e-05 23.8 0.0 3.6 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 PFH36470.1 - 5.5e-07 30.0 0.0 2.1e-06 28.2 0.1 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PFH36470.1 - 6.4e-07 29.3 0.0 0.0069 16.4 0.1 2.5 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 PFH36470.1 - 2.4e-05 24.8 3.6 0.0052 17.5 0.4 4.3 4 1 1 5 5 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 PFH36470.1 - 0.0012 18.4 0.0 0.1 12.3 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 PFH36470.1 - 0.0035 17.5 0.9 0.09 12.9 0.1 3.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 PFH36470.1 - 0.0048 17.0 0.0 1.2 9.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 PFH36470.1 - 0.0082 16.7 0.7 0.95 10.2 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 PFH36470.1 - 0.04 14.2 0.3 2.5 8.4 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH36470.1 - 0.042 14.1 0.0 0.39 11.0 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PFH36470.1 - 0.077 13.4 0.2 0.58 10.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 PFH36470.1 - 0.91 10.3 5.7 0.75 10.6 0.1 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat OTU PF02338.19 PFH36471.1 - 1.6e-14 54.5 0.0 3e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PFH36471.1 - 2.5e-05 23.8 3.9 0.029 13.8 0.0 3.0 2 1 1 3 3 3 2 Peptidase C65 Otubain Bromodomain PF00439.25 PFH36472.1 - 2.3e-22 78.9 1.4 4.3e-22 78.0 1.4 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 PFH36472.1 - 2.1e-12 47.3 0.1 4.2e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PFH36472.1 - 1.2e-08 34.9 0.8 2e-08 34.2 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PFH36472.1 - 3.2e-07 30.7 0.5 7.3e-07 29.5 0.5 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PFH36472.1 - 0.0031 17.4 0.1 0.01 15.8 0.1 1.8 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 PFH36472.1 - 0.014 15.5 0.1 0.037 14.1 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PFH36472.1 - 0.058 13.5 0.2 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ras PF00071.22 PFH36473.1 - 5.7e-56 188.6 0.0 7.7e-56 188.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH36473.1 - 1.2e-31 109.4 0.0 1.9e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH36473.1 - 5e-16 58.6 0.0 7.2e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PFH36473.1 - 5.6e-07 29.6 0.0 9.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PFH36473.1 - 2.2e-06 27.3 0.0 1.1e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PFH36473.1 - 8.5e-05 22.0 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 PFH36473.1 - 0.0028 17.4 0.0 0.0045 16.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 PFH36473.1 - 0.0071 15.8 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PFH36473.1 - 0.0075 16.2 0.0 5.2 6.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase DUF4787 PF16029.5 PFH36473.1 - 0.14 12.3 0.5 0.27 11.3 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4787) Ribosomal_L3 PF00297.22 PFH36476.1 - 5.8e-11 42.0 2.9 9e-11 41.3 1.6 1.7 1 1 1 2 2 2 1 Ribosomal protein L3 BCS1_N PF08740.11 PFH36477.1 - 1.6e-41 142.3 0.2 3.1e-41 141.4 0.2 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 PFH36477.1 - 6.5e-16 58.9 0.0 7.7e-15 55.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PFH36477.1 - 0.0012 18.9 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PFH36477.1 - 0.0014 19.0 0.5 0.0075 16.7 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 PFH36477.1 - 0.0069 16.5 0.2 0.023 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 PFH36477.1 - 0.0075 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 PFH36477.1 - 0.011 15.6 0.3 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PFH36477.1 - 0.011 16.2 0.0 0.56 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PFH36477.1 - 0.013 15.9 0.0 0.039 14.3 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 PFH36477.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 PFH36477.1 - 0.017 15.1 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain PPV_E1_C PF00519.17 PFH36477.1 - 0.03 13.1 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_25 PF13481.6 PFH36477.1 - 0.036 13.6 0.0 0.094 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 PFH36477.1 - 0.044 13.1 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 PFH36477.1 - 0.058 13.9 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.13 PFH36477.1 - 0.06 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 PFH36477.1 - 0.2 12.1 0.6 0.63 10.5 0.0 2.1 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 PFH36478.1 - 2.2e-69 233.7 0.0 2.7e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36478.1 - 2.7e-43 148.1 0.0 3.4e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH36478.1 - 2.8e-09 36.7 0.0 1.6e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PFH36478.1 - 3.5e-05 23.3 0.3 6.6e-05 22.4 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PFH36478.1 - 0.00027 20.6 0.3 0.00041 20.0 0.3 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 PFH36478.1 - 0.01 14.8 0.3 0.015 14.3 0.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 PFH36478.1 - 0.022 13.5 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 PFH36478.1 - 0.074 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family OTU PF02338.19 PFH36479.1 - 1.8e-22 80.2 0.1 3.8e-22 79.1 0.0 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PFH36479.1 - 2.2e-06 27.3 0.2 0.0033 16.9 0.0 2.5 3 0 0 3 3 3 2 Peptidase C65 Otubain XRN_N PF03159.18 PFH36479.1 - 0.32 10.4 0.0 0.32 10.4 0.0 1.9 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus OmpH PF03938.14 PFH36479.1 - 1.3 9.4 19.4 0.3 11.4 11.5 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1764 PF08576.10 PFH36479.1 - 9.8 7.2 9.6 21 6.1 0.1 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) PPR_2 PF13041.6 PFH36480.1 - 4e-41 139.0 0.0 1e-08 35.2 0.0 8.6 4 3 4 8 8 8 7 PPR repeat family PPR_3 PF13812.6 PFH36480.1 - 2.5e-32 110.7 0.0 1.4e-08 34.7 0.0 6.9 3 1 4 7 7 7 7 Pentatricopeptide repeat domain PPR_long PF17177.4 PFH36480.1 - 2e-29 102.5 0.6 1.2e-12 47.7 0.0 3.4 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 PFH36480.1 - 1.4e-21 75.2 5.1 0.016 15.5 0.0 9.7 10 0 0 10 10 10 5 PPR repeat PPR_1 PF12854.7 PFH36480.1 - 3e-19 68.4 0.0 0.018 14.7 0.0 7.7 7 0 0 7 7 7 6 PPR repeat TPR_19 PF14559.6 PFH36480.1 - 1.2e-06 28.9 0.7 0.28 11.7 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 PFH36480.1 - 0.00019 22.0 6.3 7.2 7.7 0.0 6.0 4 1 1 5 5 5 2 Tetratricopeptide repeat RabGAP-TBC PF00566.18 PFH36480.1 - 0.0041 16.8 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SelB-wing_2 PF09106.11 PFH36480.1 - 0.02 15.1 1.4 4.5 7.6 0.0 3.8 4 0 0 4 4 4 0 Elongation factor SelB, winged helix ECSIT PF06239.11 PFH36480.1 - 0.036 13.2 0.0 3.6 6.6 0.0 3.4 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway WD40 PF00400.32 PFH36481.1 - 8e-29 99.3 15.9 1.1e-05 26.0 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat PRP4 PF08799.11 PFH36481.1 - 3.4e-11 42.5 1.9 3.4e-11 42.5 1.9 2.5 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 PFH36481.1 - 2.7e-08 34.0 4.4 0.098 13.0 0.0 4.8 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PFH36481.1 - 0.37 9.4 2.6 5.9 5.4 0.1 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 SHIPPO-rpt PF07004.12 PFH36483.1 - 9.4e-38 127.4 65.3 4.1e-05 24.3 0.3 10.4 10 0 0 10 10 10 10 Sperm-tail PG-rich repeat HU-CCDC81_euk_1 PF14908.6 PFH36484.1 - 5.1e-24 84.3 0.0 1.3e-23 83.0 0.0 1.6 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 PFH36484.1 - 3.9e-16 58.9 0.4 3e-14 52.9 0.1 2.2 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 Bac_DNA_binding PF00216.21 PFH36484.1 - 0.00012 22.2 0.0 0.0034 17.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial DNA-binding protein HU-HIG PF18291.1 PFH36484.1 - 0.0096 16.0 0.0 0.032 14.3 0.0 2.0 2 1 0 2 2 2 1 HU domain fused to wHTH, Ig, or Glycine-rich motif Ribosomal_S26e PF01283.19 PFH36485.1 - 5.3e-50 168.4 9.2 6.1e-50 168.2 9.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e SRP19 PF01922.17 PFH36485.1 - 0.029 15.3 0.2 0.042 14.8 0.2 1.2 1 0 0 1 1 1 0 SRP19 protein HIT PF01230.23 PFH36486.1 - 6.7e-25 87.7 0.0 1e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 PFH36486.1 - 2.8e-10 40.7 0.0 3.8e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding PHD PF00628.29 PFH36487.1 - 0.0035 17.2 2.3 0.0091 15.9 2.3 1.7 1 0 0 1 1 1 1 PHD-finger zinc_ribbon_10 PF10058.9 PFH36487.1 - 0.33 10.7 1.8 0.61 9.9 1.2 1.8 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Exo_endo_phos PF03372.23 PFH36489.1 - 2.1e-16 60.2 0.0 6.4e-16 58.6 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Acetyltransf_1 PF00583.25 PFH36490.1 - 4.1e-11 43.2 0.0 6.9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PFH36490.1 - 3.8e-07 30.0 0.0 6.9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 PFH36490.1 - 9.1e-07 28.9 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PFH36490.1 - 3.8e-05 24.0 0.1 6.8e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PFH36490.1 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DNA_methylase PF00145.17 PFH36491.1 - 7.1e-22 78.2 0.0 1.9e-13 50.5 0.0 3.4 4 0 0 4 4 4 2 C-5 cytosine-specific DNA methylase BCAS2 PF05700.11 PFH36492.1 - 8.9e-34 117.0 5.9 6.5e-32 110.9 5.9 2.1 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) NCE101 PF11654.8 PFH36493.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 RAP PF08373.10 PFH36496.1 - 1.1e-06 28.7 0.1 1.8e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 RAP domain SOG2 PF10428.9 PFH36496.1 - 0.053 12.7 8.7 0.077 12.2 8.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein LSM PF01423.22 PFH36497.1 - 1.3e-20 72.8 0.0 2.2e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 LSM domain zf-CCCH PF00642.24 PFH36497.1 - 0.019 14.9 12.8 0.022 14.7 7.7 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SM-ATX PF14438.6 PFH36497.1 - 0.021 15.0 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Ataxin 2 SM domain zf-CCCH_3 PF15663.5 PFH36497.1 - 0.079 13.2 8.9 0.43 10.8 0.9 2.9 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 PFH36497.1 - 0.18 12.3 13.0 1.9 9.1 0.2 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 PFH36497.1 - 0.27 11.9 9.6 4.1 8.1 0.0 3.5 3 0 0 3 3 3 0 Torus domain zf_CCCH_4 PF18345.1 PFH36497.1 - 1.5 9.0 14.8 0.71 10.0 8.4 3.1 3 1 0 3 3 3 0 Zinc finger domain GRP PF07172.11 PFH36498.1 - 0.09 13.5 0.9 0.92 10.2 0.9 2.9 1 0 0 1 1 1 0 Glycine rich protein family FH2 PF02181.23 PFH36501.1 - 2.9e-24 85.9 0.0 4.8e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain LRR_6 PF13516.6 PFH36502.1 - 2e-27 92.9 16.4 0.0023 17.8 0.0 9.3 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.7 PFH36502.1 - 4.6e-06 26.9 18.3 0.025 15.0 0.2 5.0 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH36502.1 - 0.00012 21.8 12.8 0.048 13.4 0.4 4.8 2 2 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 PFH36502.1 - 0.1 13.2 17.7 22 6.1 0.2 7.4 7 1 0 7 7 7 0 Leucine Rich Repeat Ribosomal_S19 PF00203.21 PFH36503.1 - 1.2e-31 108.4 0.3 2e-31 107.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 Baculo_ME53 PF06061.11 PFH36503.1 - 0.091 12.0 0.0 0.096 11.9 0.0 1.1 1 0 0 1 1 1 0 Baculoviridae ME53 GMC_oxred_N PF00732.19 PFH36504.1 - 6.8e-23 81.5 0.1 2.5e-12 46.8 0.0 3.1 3 0 0 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.13 PFH36504.1 - 2.5e-17 63.8 0.0 3.3e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 PFH36504.1 - 0.0025 17.1 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 PFH36504.1 - 0.0042 16.7 0.0 0.013 15.1 0.1 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 PFH36504.1 - 0.0047 16.2 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 PFH36504.1 - 0.0064 17.0 0.0 0.055 14.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PFH36504.1 - 0.0064 16.1 0.1 0.016 14.8 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PFH36504.1 - 0.0094 15.1 0.0 0.036 13.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 PFH36504.1 - 0.014 15.7 0.0 0.038 14.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 PFH36504.1 - 0.018 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 PFH36504.1 - 0.024 14.9 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 PFH36504.1 - 0.039 12.7 0.0 0.061 12.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein GDI PF00996.18 PFH36504.1 - 0.11 11.1 0.0 0.85 8.1 0.0 1.9 2 0 0 2 2 2 0 GDP dissociation inhibitor RabGAP-TBC PF00566.18 PFH36505.1 - 2.9e-43 148.0 0.1 4.3e-43 147.5 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Transcrip_act PF04949.13 PFH36505.1 - 0.78 9.6 3.0 1.3 8.9 1.9 1.9 2 0 0 2 2 2 0 Transcriptional activator HHH_5 PF14520.6 PFH36506.1 - 0.0016 19.0 0.1 0.0036 17.9 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 PFH36506.1 - 0.0047 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH PF00633.23 PFH36506.1 - 0.03 14.2 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif NopRA1 PF16201.5 PFH36507.1 - 1.2e-09 38.1 4.6 4.7e-06 26.3 0.1 3.6 2 1 0 2 2 2 2 Nucleolar pre-ribosomal-associated protein 1 DUF3099 PF11298.8 PFH36508.1 - 0.14 12.3 0.7 0.26 11.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) PGF-CTERM PF18204.1 PFH36510.1 - 0.073 13.1 0.4 0.073 13.1 0.4 2.0 2 0 0 2 2 2 0 PGF-CTERM motif CLP_protease PF00574.23 PFH36512.1 - 1.1e-11 45.0 0.0 1.7e-06 28.0 0.1 3.2 3 0 0 3 3 3 3 Clp protease YGGT PF02325.17 PFH36513.1 - 3.2e-10 40.3 1.5 6.6e-10 39.3 1.5 1.5 1 0 0 1 1 1 1 YGGT family Sec1 PF00995.23 PFH36514.1 - 2.8e-95 320.7 0.0 3.2e-95 320.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family ATP11 PF06644.11 PFH36515.1 - 1.7e-32 113.3 0.0 3.4e-32 112.3 0.0 1.4 2 0 0 2 2 2 1 ATP11 protein DUF202 PF02656.15 PFH36517.1 - 0.07 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Peptidase_M20 PF01546.28 PFH36518.1 - 2e-14 53.8 0.0 6.6e-06 26.0 0.0 4.8 5 0 0 5 5 5 3 Peptidase family M20/M25/M40 WD40 PF00400.32 PFH36518.1 - 3.4e-06 27.7 18.1 0.66 11.0 0.4 7.0 7 0 0 7 7 7 2 WD domain, G-beta repeat M20_dimer PF07687.14 PFH36518.1 - 4.3e-06 26.6 0.0 2.3e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase dimerisation domain GATase_6 PF13522.6 PFH36518.1 - 0.0092 16.2 0.0 0.04 14.1 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain ANAPC4_WD40 PF12894.7 PFH36518.1 - 0.1 12.9 0.0 2.9 8.2 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain LIP PF03583.14 PFH36518.1 - 0.21 10.9 1.2 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Secretory lipase Cupin_2 PF07883.11 PFH36519.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain Clathrin_lg_ch PF01086.17 PFH36520.1 - 9.3e-15 55.3 10.5 1.4e-14 54.8 10.5 1.2 1 0 0 1 1 1 1 Clathrin light chain MDMPI_N PF11716.8 PFH36520.1 - 0.18 12.5 3.0 0.37 11.5 3.0 1.6 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Cupin_4 PF08007.12 PFH36520.1 - 0.21 11.0 3.0 0.32 10.4 3.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein PBECR5 PF18814.1 PFH36520.1 - 0.59 10.0 8.3 0.96 9.3 8.3 1.2 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 PA26 PF04636.13 PFH36520.1 - 2.2 7.1 5.3 3.1 6.6 5.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) IBR PF01485.21 PFH36521.1 - 2e-06 27.9 10.8 0.00011 22.3 1.2 4.0 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-rbx1 PF12678.7 PFH36521.1 - 0.0041 17.4 0.3 0.013 15.7 0.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 PFH36521.1 - 0.0074 16.6 1.7 0.0074 16.6 1.7 3.9 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 PFH36521.1 - 0.0091 15.9 1.5 0.0091 15.9 1.5 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PFH36521.1 - 9.5 6.5 19.1 21 5.4 0.4 3.7 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING CNDH2_M PF16869.5 PFH36522.1 - 1 10.1 4.9 0.68 10.6 1.0 2.7 2 0 0 2 2 2 0 PF16858 SAG PF04092.13 PFH36523.1 - 7.9e-35 120.5 13.4 8.8e-18 65.4 0.5 2.4 2 0 0 2 2 2 2 SRS domain AAA PF00004.29 PFH36523.1 - 1.7e-14 54.4 0.1 1e-13 51.9 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 PFH36523.1 - 7.8e-12 45.3 0.0 4e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 PFH36523.1 - 9e-12 45.3 0.0 3.3e-11 43.4 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 PFH36523.1 - 7.5e-08 32.5 0.0 2.1e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 PFH36523.1 - 1.4e-06 28.8 0.0 4.3e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PFH36523.1 - 2.7e-06 27.7 0.0 6.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PFH36523.1 - 1.3e-05 25.0 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 PFH36523.1 - 0.00022 21.5 0.0 0.00056 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 PFH36523.1 - 0.00026 20.9 0.0 0.00053 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 PFH36523.1 - 0.00058 19.2 0.1 0.0011 18.3 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.12 PFH36523.1 - 0.00064 19.5 0.0 0.002 17.9 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 PFH36523.1 - 0.001 19.4 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 PFH36523.1 - 0.0031 16.7 0.0 0.005 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 PFH36523.1 - 0.0072 16.3 0.0 0.075 13.0 0.0 2.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 PFH36523.1 - 0.008 16.2 0.0 0.19 11.7 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 PFH36523.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 PFH36523.1 - 0.023 14.2 0.4 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Torsin PF06309.11 PFH36523.1 - 0.096 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Torsin DEAD PF00270.29 PFH36523.1 - 0.11 12.3 0.0 1 9.1 0.0 2.4 3 0 0 3 3 2 0 DEAD/DEAH box helicase AAA_24 PF13479.6 PFH36523.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PFH36523.1 - 0.14 12.3 0.0 0.51 10.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain MerR PF00376.23 PFH36523.1 - 0.19 11.5 0.2 0.4 10.5 0.2 1.5 1 0 0 1 1 1 0 MerR family regulatory protein Choline_transpo PF04515.12 PFH36524.1 - 2.3e-45 155.2 24.4 2.3e-45 155.2 24.4 1.7 2 0 0 2 2 2 1 Plasma-membrane choline transporter KH_1 PF00013.29 PFH36525.1 - 1.2e-15 57.1 0.0 4.6e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 PFH36525.1 - 0.0026 17.5 0.3 0.5 10.2 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 PFH36525.1 - 0.12 12.3 0.4 7.5 6.5 0.0 2.5 2 0 0 2 2 2 0 KH domain Pkinase PF00069.25 PFH36526.1 - 1.2e-35 123.2 0.0 8.5e-13 48.3 0.0 4.3 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36526.1 - 5.8e-12 45.4 0.0 3.2e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 PFH36526.1 - 0.00023 20.1 0.0 0.00048 19.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_8 PF13833.6 PFH36526.1 - 0.00083 19.2 0.1 0.0056 16.5 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 PFH36526.1 - 0.0018 18.7 0.0 0.58 10.7 0.0 3.0 2 1 0 2 2 2 1 EF-hand domain pair APH PF01636.23 PFH36526.1 - 0.0024 17.8 0.3 0.0091 15.9 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PFH36526.1 - 0.0026 17.2 0.2 2.1 7.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 PFH36526.1 - 0.0044 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_6 PF13405.6 PFH36526.1 - 0.084 12.9 0.0 14 5.9 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain FTA2 PF13095.6 PFH36526.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Wtap PF17098.5 PFH36527.1 - 2e-39 135.0 9.6 2e-39 135.0 9.6 1.9 2 0 0 2 2 2 1 WTAP/Mum2p family CENP-F_leu_zip PF10473.9 PFH36527.1 - 0.002 18.1 4.6 0.002 18.1 4.6 2.5 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 PFH36527.1 - 0.018 14.0 10.1 0.061 12.2 10.1 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein KASH_CCD PF14662.6 PFH36527.1 - 0.032 14.1 13.4 0.04 13.7 9.2 2.7 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Filament PF00038.21 PFH36527.1 - 0.033 13.8 10.5 0.021 14.4 3.9 2.4 2 0 0 2 2 2 0 Intermediate filament protein FPP PF05911.11 PFH36527.1 - 0.054 11.7 9.5 0.08 11.1 8.2 1.5 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil TEX13 PF15186.6 PFH36527.1 - 0.065 12.9 6.7 0.11 12.2 2.5 2.8 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family Bacillus_HBL PF05791.11 PFH36527.1 - 0.14 11.9 1.3 0.36 10.6 1.1 1.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) SHE3 PF17078.5 PFH36527.1 - 0.21 11.3 3.6 0.35 10.5 3.6 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 BLOC1_2 PF10046.9 PFH36527.1 - 0.22 11.8 2.6 0.33 11.3 0.9 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PspA_IM30 PF04012.12 PFH36527.1 - 0.4 10.2 15.0 0.46 10.0 2.5 3.1 1 1 2 3 3 3 0 PspA/IM30 family Prefoldin PF02996.17 PFH36527.1 - 0.43 10.5 3.9 21 5.1 0.3 3.0 2 1 0 2 2 2 0 Prefoldin subunit APG6_N PF17675.1 PFH36527.1 - 0.7 10.4 20.7 0.38 11.3 14.3 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF2730 PF10805.8 PFH36527.1 - 1.1 9.4 3.5 6.8 6.9 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) TPR_MLP1_2 PF07926.12 PFH36527.1 - 1.3 9.1 14.5 0.044 13.8 3.6 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 PFH36527.1 - 1.3 9.7 9.4 0.51 11.0 2.0 3.0 1 1 1 2 2 2 0 Initiation control protein YabA Rx_N PF18052.1 PFH36527.1 - 1.9 8.9 9.0 9.2 6.6 0.2 3.3 1 1 2 3 3 3 0 Rx N-terminal domain FlaC_arch PF05377.11 PFH36527.1 - 2.8 8.4 5.0 9.8 6.7 0.2 3.6 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) CCDC-167 PF15188.6 PFH36527.1 - 4.7 7.6 9.7 9.4 6.7 1.9 3.4 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 SlyX PF04102.12 PFH36527.1 - 4.8 7.9 14.3 0.44 11.2 2.4 3.8 2 1 1 4 4 4 0 SlyX Cep57_CLD_2 PF14197.6 PFH36527.1 - 6.5 6.9 13.4 5.6 7.1 5.2 3.3 2 1 1 3 3 2 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 PFH36527.1 - 7.4 7.1 22.3 1.5e+02 2.9 3.3 4.2 2 1 1 3 3 3 0 Cell division protein ZapB CENP-H PF05837.12 PFH36527.1 - 8.1 6.9 11.0 1.1 9.7 3.3 3.1 1 1 0 2 2 2 0 Centromere protein H (CENP-H) Arf PF00025.21 PFH36528.1 - 5.8e-70 234.3 0.0 6.6e-70 234.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 PFH36528.1 - 4e-12 46.0 3.8 1.9e-07 30.6 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 PFH36528.1 - 1.2e-11 44.8 0.0 1.8e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PFH36528.1 - 1e-10 41.4 0.0 1.3e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 PFH36528.1 - 2.7e-08 33.5 0.0 3.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PFH36528.1 - 6.1e-07 29.0 0.0 8.5e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PFH36528.1 - 1.4e-05 25.1 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PFH36528.1 - 1.8e-05 24.4 0.0 0.00013 21.6 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 PFH36528.1 - 0.084 12.8 0.0 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain PPK2 PF03976.14 PFH36528.1 - 0.095 12.2 0.1 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) TniB PF05621.11 PFH36528.1 - 0.15 11.4 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein FeoB_N PF02421.18 PFH36528.1 - 0.17 11.4 0.1 0.76 9.3 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B CNDH2_C PF16858.5 PFH36529.1 - 6e-15 55.9 0.2 3.7e-14 53.3 0.0 2.3 2 1 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 PFH36529.1 - 2.2e-05 24.6 0.0 0.00014 22.1 0.0 2.2 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal NifU PF01106.17 PFH36531.1 - 4.4e-22 78.0 0.0 9.1e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 PFH36531.1 - 2.1e-20 72.5 0.0 4.3e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal SUZ-C PF12901.7 PFH36531.1 - 0.019 15.0 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 SUZ-C motif Rhomboid PF01694.22 PFH36533.1 - 1.8e-23 83.2 12.0 2.5e-23 82.8 12.0 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 PFH36533.1 - 0.24 12.0 5.4 0.052 14.1 1.3 1.9 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) RuBisCO_large_N PF02788.16 PFH36534.1 - 0.11 12.7 0.1 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain Surfac_D-trimer PF09006.11 PFH36535.1 - 0.91 9.5 3.5 23 5.0 0.3 5.5 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation PI31_Prot_C PF08577.11 PFH36537.1 - 1e-09 39.4 14.2 1e-09 39.4 14.2 3.0 3 0 0 3 3 3 1 PI31 proteasome regulator zf-HIT PF04438.16 PFH36538.1 - 1.9e-07 30.8 12.2 3.2e-07 30.1 12.2 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 PFH36538.1 - 0.035 14.2 10.4 0.092 12.9 10.4 1.7 1 0 0 1 1 1 0 MYND finger ubiquitin PF00240.23 PFH36539.1 - 7.5e-12 44.8 0.0 1.1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PFH36539.1 - 0.00079 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 PFH36539.1 - 0.0022 18.3 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 PFH36539.1 - 0.011 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 PFH36539.1 - 0.097 13.4 0.3 0.68 10.7 0.0 2.5 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD DUF2407 PF10302.9 PFH36539.1 - 0.13 12.9 0.0 0.37 11.4 0.0 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Biopterin_H PF00351.21 PFH36544.1 - 4.8e-123 410.4 0.0 6.4e-123 410.0 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 PFH36544.1 - 0.00093 18.9 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 ACT domain DUF3128 PF11326.8 PFH36546.1 - 0.079 13.3 4.2 2.1 8.8 4.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Cpn60_TCP1 PF00118.24 PFH36547.1 - 7.4e-132 440.4 6.7 8.4e-132 440.3 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LRR_11 PF18831.1 PFH36547.1 - 0.2 11.3 2.6 3.5 7.3 0.1 2.5 2 0 0 2 2 2 0 Leucine-rich repeat SAG PF04092.13 PFH36550.1 - 4.1e-17 63.2 9.5 3.1e-08 34.5 3.2 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36551.1 - 2.4e-17 63.9 5.3 3.2e-09 37.7 3.2 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36552.1 - 9.3e-15 55.6 7.6 1.8e-08 35.3 4.1 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36553.1 - 8.4e-25 88.1 29.5 7.2e-06 26.8 1.9 4.4 4 0 0 4 4 4 4 SRS domain SAG PF04092.13 PFH36554.1 - 5.6e-16 59.5 32.8 1.9e-07 31.9 3.5 4.3 4 0 0 4 4 4 4 SRS domain DNA_pol_A_exo1 PF01612.20 PFH36555.1 - 1.9e-17 63.5 0.0 2.8e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease PP2C PF00481.21 PFH36556.1 - 2e-44 152.2 0.0 3.5e-41 141.5 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 PFH36556.1 - 0.24 11.0 1.2 0.75 9.4 0.5 2.1 2 1 0 2 2 2 0 Protein phosphatase 2C MFS_1 PF07690.16 PFH36557.1 - 7.8e-08 31.6 23.1 1.8e-05 23.8 4.6 3.4 3 1 1 4 4 4 3 Major Facilitator Superfamily zf-C3HC4_3 PF13920.6 PFH36559.1 - 6.7e-12 45.1 10.8 1e-11 44.5 10.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PFH36559.1 - 4.9e-08 32.7 11.0 8.1e-08 32.0 11.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PFH36559.1 - 0.00019 21.7 14.3 0.00029 21.1 14.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PFH36559.1 - 0.011 15.5 14.5 0.018 14.9 14.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PFH36559.1 - 0.12 12.1 10.6 0.2 11.5 10.6 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TauE PF01925.19 PFH36560.1 - 7e-23 81.5 27.1 3.2e-12 46.6 2.2 2.2 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE MtN3_slv PF03083.16 PFH36561.1 - 2e-20 72.6 5.1 4.3e-10 39.5 0.5 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange zf-PHD-like PF15446.6 PFH36564.1 - 0.045 13.4 5.1 0.17 11.5 3.2 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain SEP PF08059.13 PFH36565.1 - 7.3e-25 87.3 0.2 2e-24 85.9 0.1 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 PFH36565.1 - 2.3e-14 53.4 0.0 3.5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 UBX domain KH_1 PF00013.29 PFH36566.1 - 0.0053 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 KH domain Roughex PF06020.11 PFH36566.1 - 0.092 11.8 2.6 0.15 11.1 2.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Snf7 PF03357.21 PFH36569.1 - 1.2e-20 73.8 2.6 1.7e-20 73.4 2.6 1.2 1 0 0 1 1 1 1 Snf7 RNase_H PF00075.24 PFH36570.1 - 7e-29 100.8 0.0 1.3e-10 41.6 0.0 3.2 3 0 0 3 3 3 3 RNase H CKS PF01111.19 PFH36571.1 - 2.6e-20 72.5 0.2 3.9e-20 71.9 0.2 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PDEase_I PF00233.19 PFH36573.1 - 1.2e-60 205.2 0.4 1.8e-60 204.6 0.4 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Cofilin_ADF PF00241.20 PFH36574.1 - 7.9e-29 99.9 0.0 1e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein FAD_binding_3 PF01494.19 PFH36579.1 - 9.2e-60 202.7 0.2 3.3e-32 112.1 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.24 PFH36579.1 - 0.00014 21.1 0.1 0.00024 20.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 PFH36579.1 - 0.0013 18.1 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PFH36579.1 - 0.0043 16.3 0.0 0.007 15.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PFH36579.1 - 0.0067 15.5 0.2 0.011 14.8 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 PFH36579.1 - 0.084 11.6 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 PFH36579.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family tRNA-synt_2 PF00152.20 PFH36580.1 - 1.2e-42 146.1 0.0 3.1e-37 128.3 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 PFH36580.1 - 6.7e-05 22.5 0.0 0.032 13.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 PFH36580.1 - 0.00056 19.8 0.0 0.0013 18.7 0.0 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Solute_trans_a PF03619.16 PFH36581.1 - 9.9e-43 146.6 23.6 2.2e-20 73.3 6.7 3.2 3 0 0 3 3 3 3 Organic solute transporter Ostalpha Nramp PF01566.18 PFH36582.1 - 0.0091 15.0 1.1 0.067 12.2 0.1 2.1 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein BSD PF03909.17 PFH36583.1 - 8.1e-09 35.4 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 BSD domain Ribosomal_L27A PF00828.19 PFH36584.1 - 2.8e-17 63.6 0.0 6.4e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TerB_N PF13208.6 PFH36584.1 - 0.0073 16.0 0.4 0.017 14.9 0.4 1.6 1 0 0 1 1 1 1 TerB N-terminal domain ZapB PF06005.12 PFH36584.1 - 0.12 12.8 0.1 0.12 12.8 0.1 4.7 4 1 0 4 4 4 0 Cell division protein ZapB ASH PF15780.5 PFH36585.1 - 7.6e-11 42.1 3.7 0.28 11.4 0.1 8.2 8 1 0 8 8 8 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 PFH36585.1 - 9.4e-06 25.7 0.1 0.008 16.3 0.1 3.8 4 0 0 4 4 4 2 Flagellar-associated PapD-like CAP PF00188.26 PFH36586.1 - 8.4e-17 62.2 9.3 8.7e-13 49.2 3.5 2.8 3 0 0 3 3 3 2 Cysteine-rich secretory protein family Mucin PF01456.17 PFH36586.1 - 6.6e-07 29.4 30.8 6.6e-07 29.4 30.8 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein Med3 PF11593.8 PFH36586.1 - 0.022 13.9 11.7 0.049 12.8 11.7 1.7 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Dicty_REP PF05086.12 PFH36586.1 - 0.84 7.5 11.2 1.2 7.0 11.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AJAP1_PANP_C PF15298.6 PFH36586.1 - 2.2 8.5 22.9 4.5 7.4 22.9 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus IMCp PF12314.8 PFH36587.1 - 1.1e-17 64.1 22.5 1.1e-17 64.1 22.5 3.9 1 1 1 3 3 3 2 Inner membrane complex protein RMI1_N PF08585.12 PFH36588.1 - 9.6e-26 90.9 1.2 1.4e-24 87.1 0.0 2.7 2 1 0 2 2 2 1 RecQ mediated genome instability protein Voldacs PF03517.13 PFH36589.1 - 1.3e-26 93.4 1.3 1.3e-26 93.4 1.3 1.9 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling PH_TFIIH PF08567.11 PFH36589.1 - 0.046 14.1 0.0 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain Vps36_ESCRT-II PF11605.8 PFH36589.1 - 0.061 13.5 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 RINGv PF12906.7 PFH36590.1 - 1.7e-11 44.0 5.4 3.2e-11 43.2 5.4 1.5 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.26 PFH36590.1 - 1.8e-10 41.0 0.0 5.2e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PFH36590.1 - 1.3e-07 31.8 0.1 1.4e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FANCL_C PF11793.8 PFH36590.1 - 0.52 10.5 2.9 1.4 9.1 2.5 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_2 PF13639.6 PFH36590.1 - 1.4 9.3 4.7 3 8.3 4.7 1.6 1 0 0 1 1 1 0 Ring finger domain SprB PF13573.6 PFH36593.1 - 0.12 12.2 16.9 35 4.3 0.2 5.3 5 0 0 5 5 5 0 SprB repeat SRPRB PF09439.10 PFH36594.1 - 3.4e-24 85.3 0.0 3.6e-23 81.9 0.0 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 PFH36594.1 - 2.5e-14 53.1 0.0 2.6e-13 49.8 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PFH36594.1 - 7.7e-08 32.6 0.0 3.1e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 PFH36594.1 - 1.7e-07 30.8 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PFH36594.1 - 1.5e-06 27.9 0.0 2.6e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 PFH36594.1 - 3.9e-06 26.6 0.0 3.2e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 PFH36594.1 - 4.7e-06 26.7 0.0 8.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 PFH36594.1 - 0.00041 20.8 2.7 0.0011 19.4 2.7 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 PFH36594.1 - 0.0016 18.4 0.2 0.24 11.3 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 PFH36594.1 - 0.0042 16.3 0.0 2.3 7.3 0.0 2.4 2 1 0 2 2 2 2 G-protein alpha subunit ABC_tran PF00005.27 PFH36594.1 - 0.0081 16.7 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.12 PFH36594.1 - 0.012 15.6 1.0 0.29 11.0 1.0 2.2 1 1 0 1 1 1 0 NACHT domain PduV-EutP PF10662.9 PFH36594.1 - 0.042 13.6 0.0 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 PFH36594.1 - 0.051 13.1 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.6 PFH36594.1 - 0.053 13.8 0.1 0.47 10.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain ODC_AZ PF02100.17 PFH36594.1 - 0.059 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme cobW PF02492.19 PFH36594.1 - 0.087 12.4 0.4 12 5.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 PFH36594.1 - 0.091 12.5 0.0 0.68 9.7 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PRK PF00485.18 PFH36594.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Topoisom_bac PF01131.20 PFH36595.1 - 1e-104 350.8 0.0 1.3e-104 350.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 PFH36595.1 - 1.5e-16 60.4 0.0 3.4e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF86 PF01934.17 PFH36595.1 - 0.021 14.7 0.0 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF86 FoP_duplication PF13865.6 PFH36595.1 - 4.7 7.8 10.8 9.5 6.8 10.8 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Sin_N PF04801.13 PFH36596.1 - 1.6e-81 274.7 0.0 1.3e-78 265.2 0.0 2.4 2 0 0 2 2 2 2 Sin-like protein conserved region DUF1729 PF08354.10 PFH36596.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Filo_glycop PF01611.16 PFH36597.1 - 8.3 5.2 7.7 0.24 10.3 0.1 1.9 1 1 1 2 2 2 0 Filovirus glycoprotein AP2 PF00847.20 PFH36598.1 - 4.4e-33 113.3 14.9 1.5e-12 47.5 1.2 3.4 3 0 0 3 3 3 3 AP2 domain ACDC PF14733.6 PFH36599.1 - 8.1e-20 70.9 0.1 1e-19 70.6 0.1 1.1 1 0 0 1 1 1 1 AP2-coincident C-terminal 5_nucleotid_C PF02872.18 PFH36600.1 - 9.6e-09 35.6 0.0 1.2e-07 32.1 0.0 2.4 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain DUF2569 PF10754.9 PFH36601.1 - 0.037 14.5 0.6 0.11 12.9 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) RRM_1 PF00076.22 PFH36602.1 - 5e-33 112.7 0.1 2e-16 59.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH36602.1 - 2.9e-07 30.5 0.0 0.007 16.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 PFH36602.1 - 0.00023 21.1 0.0 0.015 15.3 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 PFH36602.1 - 0.0037 17.3 0.0 0.46 10.5 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif OB_RNB PF08206.11 PFH36602.1 - 0.055 13.1 0.5 2.6 7.8 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Bromodomain PF00439.25 PFH36606.1 - 1.7e-15 56.9 0.0 2.6e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain BUD22 PF09073.10 PFH36607.1 - 0.011 15.1 12.8 0.02 14.3 12.8 1.4 1 0 0 1 1 1 0 BUD22 DUF4614 PF15391.6 PFH36607.1 - 0.012 15.6 11.5 0.02 14.9 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SDA1 PF05285.12 PFH36607.1 - 0.015 14.8 8.7 0.023 14.1 8.7 1.2 1 0 0 1 1 1 0 SDA1 AF-4 PF05110.13 PFH36607.1 - 0.023 12.8 12.8 0.03 12.5 12.8 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.12 PFH36607.1 - 0.023 14.4 7.3 0.045 13.5 7.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Hid1 PF12722.7 PFH36607.1 - 0.41 8.7 2.0 0.5 8.4 2.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Smg8_Smg9 PF10220.9 PFH36607.1 - 1.3 7.3 4.5 1.7 6.9 4.5 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Nop14 PF04147.12 PFH36607.1 - 3.7 5.6 12.3 5.2 5.1 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 PFH36607.1 - 3.9 6.2 9.5 5.3 5.7 9.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PGM_PMM_I PF02878.16 PFH36608.1 - 1.8e-15 56.9 0.0 1.7e-06 27.8 0.0 2.8 3 0 0 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 PFH36608.1 - 1.1e-07 31.9 0.1 6.1e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 PFH36608.1 - 0.088 13.4 0.0 0.8 10.4 0.0 2.6 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SAG PF04092.13 PFH36609.1 - 3.1e-98 325.7 16.0 8.5e-08 33.0 0.0 14.2 14 0 0 14 14 14 14 SRS domain COP-gamma_platf PF08752.10 PFH36609.1 - 0.019 15.1 0.0 79 3.3 0.0 6.4 10 0 0 10 10 10 0 Coatomer gamma subunit appendage platform subdomain DNA_pol_B PF00136.21 PFH36610.1 - 2.6e-62 211.0 0.0 8.6e-62 209.3 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 PFH36610.1 - 0.00047 20.6 3.1 0.0012 19.2 0.1 2.7 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Cyclin_N PF00134.23 PFH36611.1 - 4e-11 42.8 0.0 1e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PFH36611.1 - 0.00052 20.1 0.0 0.0083 16.2 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain BCNT PF07572.12 PFH36613.1 - 9.7e-15 54.4 0.2 9.7e-15 54.4 0.2 2.2 2 0 0 2 2 2 1 Bucentaur or craniofacial development BLOC1_2 PF10046.9 PFH36613.1 - 0.0036 17.6 0.2 0.0094 16.2 0.2 1.6 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2428 PF10350.9 PFH36617.1 - 4.2e-26 91.8 0.8 4.9e-25 88.3 0.8 2.7 1 1 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.6 PFH36617.1 - 2.7 8.4 7.6 54 4.3 0.1 5.4 5 0 0 5 5 5 0 HEAT repeats Oxysterol_BP PF01237.18 PFH36619.1 - 4.8e-126 420.6 0.0 7.3e-126 420.0 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 PFH36619.1 - 6.4e-10 39.5 0.1 1.3e-09 38.5 0.1 1.5 1 0 0 1 1 1 1 PH domain CENP-Q PF13094.6 PFH36619.1 - 0.018 15.3 0.2 0.018 15.3 0.2 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit T3SS_TC PF06511.11 PFH36619.1 - 0.035 13.5 0.6 0.069 12.5 0.6 1.4 1 0 0 1 1 1 0 Type III secretion systems tip complex components DUF1043 PF06295.12 PFH36619.1 - 0.099 12.7 1.6 0.22 11.5 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) HAUS-augmin3 PF14932.6 PFH36619.1 - 0.12 12.0 3.4 0.22 11.1 3.4 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 tRNA_anti-codon PF01336.25 PFH36621.1 - 0.1 12.6 0.0 18 5.4 0.0 2.5 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain UDPGP PF01704.18 PFH36622.1 - 7.4e-23 80.9 0.0 1.2e-21 76.9 0.0 2.6 3 1 0 3 3 3 1 UTP--glucose-1-phosphate uridylyltransferase DUF3689 PF12463.8 PFH36623.1 - 4e-42 144.6 0.5 2.4e-15 56.6 0.0 5.1 5 0 0 5 5 5 5 Protein of unknown function (DUF3689) CAF1C_H4-bd PF12265.8 PFH36624.1 - 9.2e-16 57.9 0.7 2.7e-15 56.4 0.7 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 PFH36624.1 - 8.2e-11 42.3 11.1 0.0017 19.1 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Pox_A11 PF05061.13 PFH36624.1 - 0.068 12.4 1.0 0.17 11.1 1.0 1.7 1 0 0 1 1 1 0 Poxvirus A11 Protein DehI PF10778.9 PFH36624.1 - 0.14 12.3 4.6 0.38 10.9 4.6 1.8 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI NRBF2 PF08961.10 PFH36624.1 - 3.1 7.4 15.4 0.69 9.5 7.2 2.8 3 0 0 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator Prominin PF05478.11 PFH36624.1 - 9.4 4.1 14.6 5.1 4.9 12.0 1.7 1 1 1 2 2 2 0 Prominin Xpo1 PF08389.12 PFH36625.1 - 1.4e-06 28.5 7.5 8.2e-05 22.7 0.5 4.3 4 0 0 4 4 4 2 Exportin 1-like protein CASP_C PF08172.12 PFH36625.1 - 0.029 13.7 1.8 0.72 9.1 0.3 2.4 2 0 0 2 2 2 0 CASP C terminal DEAD PF00270.29 PFH36626.1 - 2.2e-18 66.6 0.0 3.6e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH36626.1 - 3.8e-15 56.2 0.0 1e-14 54.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 PFH36626.1 - 1.3e-14 54.7 7.4 1.7e-14 54.3 5.3 2.4 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 PFH36626.1 - 1.2e-05 25.4 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.23 PFH36626.1 - 0.0025 17.7 0.0 0.0025 17.7 0.0 2.1 2 0 0 2 2 2 1 HRDC domain zf-RING_2 PF13639.6 PFH36627.1 - 4e-06 27.1 10.5 9.7e-06 25.8 10.5 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 PFH36627.1 - 0.00013 22.1 6.0 0.0003 20.9 6.0 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 PFH36627.1 - 0.00037 20.7 9.4 0.001 19.3 9.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING-like PF08746.11 PFH36627.1 - 0.01 16.1 4.3 0.036 14.4 4.3 2.0 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 PFH36627.1 - 0.014 15.5 4.5 0.029 14.4 4.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 PFH36627.1 - 0.055 13.4 10.5 0.12 12.3 10.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 PFH36627.1 - 0.3 11.2 6.9 0.67 10.1 6.9 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 PFH36627.1 - 0.38 10.7 9.9 0.96 9.3 9.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PFH36627.1 - 0.67 9.6 5.3 1.7 8.3 5.3 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 PFH36627.1 - 6 6.8 9.1 13 5.7 9.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SNF PF00209.18 PFH36628.1 - 1.9e-91 307.4 36.3 3.9e-52 177.6 17.0 2.4 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family ThiF PF00899.21 PFH36629.1 - 2.4e-59 200.6 0.0 3.7e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 PFH36629.1 - 2.1e-23 82.3 0.2 3.7e-23 81.5 0.2 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 PFH36629.1 - 0.0044 17.1 0.5 0.0093 16.0 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.6 PFH36629.1 - 0.013 16.1 0.0 0.025 15.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 PFH36629.1 - 0.079 12.9 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site SR-25 PF10500.9 PFH36629.1 - 2.4 7.7 12.6 3.7 7.1 12.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4614 PF15391.6 PFH36630.1 - 9.6 6.2 9.3 34 4.4 9.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) FAIM1 PF06905.13 PFH36631.1 - 0.00017 21.4 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Kelch_4 PF13418.6 PFH36632.1 - 3.5e-17 62.1 5.0 2e-06 27.7 0.1 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 PFH36632.1 - 1.7e-13 49.9 1.8 0.0076 15.8 0.1 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 PFH36632.1 - 8.6e-11 41.9 17.3 0.00056 20.1 0.1 8.4 9 0 0 9 9 9 3 Galactose oxidase, central domain Kelch_6 PF13964.6 PFH36632.1 - 1.2e-09 38.0 1.5 0.27 11.6 0.1 5.9 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 PFH36632.1 - 1.7e-09 37.3 6.6 0.058 13.4 0.1 6.5 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 PFH36632.1 - 4.6e-09 36.1 8.8 4.1e-05 23.4 0.0 6.3 7 0 0 7 7 7 2 Kelch motif TBCC PF07986.12 PFH36633.1 - 2.9e-16 59.3 0.0 4.2e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C SKA1 PF07160.12 PFH36634.1 - 0.17 11.7 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 CCDC53 PF10152.9 PFH36634.1 - 0.51 10.8 4.4 0.13 12.6 1.1 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Pkinase PF00069.25 PFH36636.1 - 2.2e-13 50.2 0.0 9.2e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 PFH36638.1 - 6.9e-39 133.6 0.0 2.5e-21 76.3 0.0 2.2 2 0 0 2 2 2 2 Choline/ethanolamine kinase Pkinase PF00069.25 PFH36638.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain AA_kinase PF00696.28 PFH36640.1 - 1.9e-32 112.8 0.2 2.9e-32 112.2 0.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 PFH36640.1 - 2.8e-13 49.6 1.0 8.1e-09 35.3 0.1 2.8 3 0 0 3 3 3 2 PUA domain Erf4 PF10256.9 PFH36643.1 - 0.13 12.4 0.4 1.7 8.8 0.1 2.7 3 1 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family EGF_2 PF07974.13 PFH36644.1 - 0.19 12.1 34.0 0.17 12.3 6.0 4.1 3 1 0 3 3 3 0 EGF-like domain STIMATE PF12400.8 PFH36646.1 - 6.3e-23 81.7 0.9 6.3e-23 81.7 0.9 2.0 2 0 0 2 2 2 1 STIMATE family pRN1_helical PF13010.6 PFH36648.1 - 1.6 8.7 3.3 26 4.8 0.7 3.3 2 1 0 2 2 2 0 Primase helical domain RIBIOP_C PF04950.12 PFH36649.1 - 3e-95 319.0 0.0 6.4e-95 317.9 0.0 1.6 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 PFH36649.1 - 2.2e-12 46.9 0.0 6.7e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain CLAG PF03805.13 PFH36650.1 - 0.00054 17.7 0.0 0.00092 16.9 0.0 1.2 1 0 0 1 1 1 1 Cytoadherence-linked asexual protein DUF4040 PF13244.6 PFH36650.1 - 0.11 12.6 1.5 0.16 12.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4040) DUF4680 PF15730.5 PFH36650.1 - 0.73 10.2 2.1 1.1 9.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) FAM221 PF14753.6 PFH36651.1 - 5e-20 71.9 1.0 6.9e-20 71.5 1.0 1.1 1 0 0 1 1 1 1 Protein FAM221A/B Ank_5 PF13857.6 PFH36652.1 - 2.1e-08 34.3 0.2 0.012 16.0 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PFH36652.1 - 1.9e-06 28.3 0.1 0.44 11.2 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH36652.1 - 0.0012 19.1 4.6 1.7 9.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat MMgT PF10270.9 PFH36653.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Membrane magnesium transporter Zn_Tnp_IS1 PF03811.13 PFH36654.1 - 0.14 11.9 0.1 4 7.2 0.0 2.5 2 0 0 2 2 2 0 InsA N-terminal domain Peptidase_C48 PF02902.19 PFH36655.1 - 2.5e-23 83.1 0.0 4.3e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.32 PFH36656.1 - 2.2e-17 63.1 5.3 9.7e-05 23.1 0.1 7.4 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH36656.1 - 1.5e-05 25.2 0.0 0.034 14.4 0.0 5.1 6 1 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain GrpE PF01025.19 PFH36657.1 - 2.5e-43 147.6 9.1 5.3e-43 146.6 9.1 1.5 1 1 0 1 1 1 1 GrpE UPF0242 PF06785.11 PFH36657.1 - 0.012 15.7 5.9 0.02 15.0 5.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 PFH36657.1 - 0.021 15.3 5.2 0.057 13.9 5.2 1.8 1 1 0 1 1 1 0 Cell division protein ZapB Allexi_40kDa PF05549.11 PFH36657.1 - 0.08 12.4 0.8 0.42 10.1 0.1 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein Focal_AT PF03623.13 PFH36657.1 - 0.3 11.1 4.1 0.55 10.2 4.1 1.4 1 0 0 1 1 1 0 Focal adhesion targeting region Seryl_tRNA_N PF02403.22 PFH36657.1 - 0.83 9.9 7.9 0.94 9.7 6.8 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 PFH36657.1 - 2 7.6 3.5 2.9 7.1 3.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4337 PF14235.6 PFH36657.1 - 2.2 8.4 7.5 3.4 7.7 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) CENP-H PF05837.12 PFH36657.1 - 5.8 7.4 7.6 11 6.4 7.7 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.12 PFH36657.1 - 6 6.9 14.0 1.9e+02 2.1 14.1 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 PFH36657.1 - 7 5.9 9.5 9.9 5.4 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ETF_QO PF05187.13 PFH36658.1 - 9.7e-34 115.6 0.2 3.8e-16 59.1 0.3 2.4 2 0 0 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 PFH36658.1 - 5.1e-07 29.8 0.0 2.3e-06 27.7 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PFH36658.1 - 6.2e-05 22.7 0.0 0.00031 20.4 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 PFH36658.1 - 0.00016 20.5 0.3 0.00025 19.9 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 PFH36658.1 - 0.00018 20.7 1.2 0.00037 19.7 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PFH36658.1 - 0.00019 20.8 0.0 0.0004 19.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PFH36658.1 - 0.00068 18.8 0.1 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 PFH36658.1 - 0.0017 17.8 0.3 0.0029 17.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PFH36658.1 - 0.0046 17.0 0.1 0.012 15.7 0.1 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 PFH36658.1 - 0.0049 16.1 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 PFH36658.1 - 0.0052 16.1 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 PFH36658.1 - 0.015 14.6 0.5 0.023 14.0 0.5 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4636 PF15468.6 PFH36658.1 - 0.17 11.6 0.4 0.31 10.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) GIDA PF01134.22 PFH36658.1 - 0.23 10.5 2.1 0.35 9.9 0.8 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A RRM_1 PF00076.22 PFH36660.1 - 3.8e-07 29.8 0.0 7.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 PFH36661.1 - 2.2e-05 24.1 0.0 0.025 14.2 0.0 3.0 3 0 0 3 3 3 2 Ras family Roc PF08477.13 PFH36661.1 - 0.0002 21.5 0.0 0.92 9.7 0.0 2.6 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 PFH36661.1 - 0.028 14.8 0.0 0.13 12.7 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain R3H PF01424.22 PFH36663.1 - 0.099 12.6 0.2 0.3 11.1 0.2 1.8 1 0 0 1 1 1 0 R3H domain PAT1 PF09770.9 PFH36664.1 - 0.002 16.5 7.4 0.0028 16.0 7.4 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DnaJ_C PF01556.18 PFH36668.1 - 2e-41 141.5 0.2 2.8e-41 141.0 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PFH36668.1 - 1.2e-25 89.4 6.2 1.8e-25 88.8 6.2 1.3 1 0 0 1 1 1 1 DnaJ domain Gp-FAR-1 PF05823.12 PFH36668.1 - 0.077 13.3 1.2 5.2 7.4 0.3 2.3 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Torus PF16131.5 PFH36669.1 - 3.3e-32 111.4 2.9 3.3e-32 111.4 2.9 2.2 3 0 0 3 3 3 1 Torus domain RRM_1 PF00076.22 PFH36669.1 - 0.00027 20.7 0.0 0.00067 19.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 PFH36669.1 - 0.078 12.8 9.4 0.2 11.5 9.4 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PFH36669.1 - 1.4 9.1 9.5 4 7.6 9.5 1.9 1 0 0 1 1 1 0 Zinc finger domain DUF4890 PF16231.5 PFH36669.1 - 1.5 9.4 4.8 0.55 10.7 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4890) zf-CCCH_2 PF14608.6 PFH36669.1 - 2.5 8.7 6.6 6.5 7.4 6.6 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Phage_holin_2_4 PF16082.5 PFH36669.1 - 6.7 6.5 7.2 22 4.9 0.9 2.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like zf-CCCH PF00642.24 PFH36669.1 - 7 6.7 9.5 4.8 7.2 6.1 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.25 PFH36670.1 - 1.8e-60 204.6 0.0 2.1e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36670.1 - 7.5e-28 97.5 0.0 1e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH36670.1 - 3.6e-07 29.8 0.0 3.6e-05 23.2 0.0 2.5 1 1 2 3 3 3 1 Kinase-like APH PF01636.23 PFH36670.1 - 0.00088 19.3 0.1 0.0043 17.0 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PFH36670.1 - 0.0038 16.6 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PFH36670.1 - 0.0099 15.5 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 PFH36670.1 - 0.045 13.3 0.2 0.14 11.8 0.1 1.7 1 1 1 2 2 2 0 Choline/ethanolamine kinase Glyco_hydro_85 PF03644.13 PFH36671.1 - 0.12 11.8 0.0 0.14 11.5 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 U-box PF04564.15 PFH36674.1 - 3.7e-21 75.1 0.0 7.8e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 PFH36674.1 - 4.2e-15 54.8 6.1 5.1e-06 26.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PFH36674.1 - 8.2e-13 47.4 6.4 0.0003 20.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 PFH36674.1 - 6.5e-11 41.7 0.2 6e-06 25.9 0.0 2.7 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.6 PFH36674.1 - 1.4e-08 34.9 5.6 4.2e-05 23.8 3.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 PFH36674.1 - 2.5e-08 34.4 0.1 8e-05 23.2 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH36674.1 - 2e-07 31.1 4.3 6.3e-07 29.5 4.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 PFH36674.1 - 2.9e-06 27.0 4.9 0.67 10.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 PFH36674.1 - 3.2e-05 24.0 1.5 0.013 15.8 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PFH36674.1 - 0.0017 19.0 2.5 3.9 8.5 0.0 4.0 3 1 2 5 5 4 1 Tetratricopeptide repeat FAT PF02259.23 PFH36674.1 - 0.0024 17.1 1.5 0.15 11.2 0.1 2.2 1 1 1 2 2 2 2 FAT domain zf-NOSIP PF15906.5 PFH36674.1 - 0.0027 17.8 0.1 0.0088 16.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_MalT PF17874.1 PFH36674.1 - 0.0039 16.6 3.8 0.081 12.3 1.0 2.4 2 1 0 3 3 3 1 MalT-like TPR region Clathrin PF00637.20 PFH36674.1 - 0.0074 16.2 0.7 0.29 11.0 0.4 2.8 2 2 0 2 2 2 1 Region in Clathrin and VPS TPR_9 PF13371.6 PFH36674.1 - 0.025 14.7 0.2 6.6 7.0 0.0 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat 23S_rRNA_IVP PF05635.11 PFH36674.1 - 0.038 14.3 0.8 0.066 13.5 0.8 1.4 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein TPR_19 PF14559.6 PFH36674.1 - 0.042 14.4 2.5 4.5 7.8 0.7 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH36674.1 - 0.05 14.3 6.0 10 7.0 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RRP36 PF06102.12 PFH36674.1 - 0.062 13.3 1.4 0.092 12.7 1.1 1.4 1 1 0 1 1 1 0 rRNA biogenesis protein RRP36 TPR_7 PF13176.6 PFH36674.1 - 0.083 13.0 6.7 0.49 10.6 0.0 3.9 4 2 1 5 5 5 0 Tetratricopeptide repeat Glu_syn_central PF04898.14 PFH36674.1 - 0.13 11.7 0.3 0.23 10.9 0.3 1.4 1 1 0 1 1 1 0 Glutamate synthase central domain COG5 PF10392.9 PFH36674.1 - 0.18 12.0 1.6 0.15 12.3 0.4 1.5 2 0 0 2 2 1 0 Golgi transport complex subunit 5 DUF5345 PF17280.2 PFH36674.1 - 0.19 11.7 0.5 13 5.8 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF1707 PF08044.11 PFH36674.1 - 0.42 10.7 2.9 0.79 9.8 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) CLTH PF10607.9 PFH36675.1 - 4.3e-19 68.9 0.0 6.6e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain BRI3BP PF14965.6 PFH36675.1 - 0.0055 16.2 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 Negative regulator of p53/TP53 LisH PF08513.11 PFH36675.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 LisH Rtf2 PF04641.12 PFH36675.1 - 0.17 11.2 0.5 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger R3H-assoc PF13902.6 PFH36676.1 - 0.0045 17.4 0.0 0.0045 17.4 0.0 3.3 3 0 0 3 3 3 1 R3H-associated N-terminal domain PAPA-1 PF04795.12 PFH36676.1 - 5.3 7.9 15.4 1.1 10.1 4.3 3.6 3 0 0 3 3 3 0 PAPA-1-like conserved region WD40 PF00400.32 PFH36677.1 - 5.5e-30 103.0 8.0 7.5e-06 26.6 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH36677.1 - 2.8e-08 33.9 0.8 0.079 13.3 0.0 4.4 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PFH36677.1 - 0.00016 21.6 1.1 0.67 9.8 0.1 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 PFH36677.1 - 0.007 16.0 0.5 0.092 12.3 0.2 2.6 2 1 0 2 2 2 1 PQQ-like domain DUF4934 PF16288.5 PFH36677.1 - 0.0084 16.0 0.0 0.029 14.3 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4934) PD40 PF07676.12 PFH36677.1 - 0.03 14.3 0.2 0.079 12.9 0.2 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat ATG16 PF08614.11 PFH36678.1 - 8.1e-05 22.9 7.5 8.1e-05 22.9 7.5 2.2 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 PFH36678.1 - 0.0066 17.0 9.8 0.0066 17.0 9.8 2.2 2 0 0 2 2 2 1 Apg6 coiled-coil region Csm1_N PF18504.1 PFH36678.1 - 0.0077 16.6 3.0 0.0077 16.6 3.0 2.9 2 1 1 3 3 2 1 Csm1 N-terminal domain GAS PF13851.6 PFH36678.1 - 0.0085 15.5 6.1 0.0085 15.5 6.1 1.8 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 PFH36678.1 - 0.011 15.8 5.3 0.011 15.8 5.3 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 PFH36678.1 - 0.018 15.0 5.6 0.018 15.0 5.6 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3837 PF12939.7 PFH36678.1 - 0.037 14.4 1.0 0.091 13.2 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3837) DUF4407 PF14362.6 PFH36678.1 - 0.043 13.2 2.6 0.058 12.7 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.6 PFH36678.1 - 0.044 13.4 11.9 0.022 14.4 6.8 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Sec34 PF04136.15 PFH36678.1 - 0.054 13.4 5.3 0.11 12.3 5.3 1.6 1 0 0 1 1 1 0 Sec34-like family PEP-utilisers_N PF05524.13 PFH36678.1 - 0.059 13.5 3.3 0.11 12.6 3.3 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal zf-C4H2 PF10146.9 PFH36678.1 - 0.19 12.0 7.0 0.14 12.4 5.3 1.6 1 1 0 2 2 2 0 Zinc finger-containing protein LETM1 PF07766.13 PFH36678.1 - 0.2 10.9 5.7 0.13 11.6 1.9 1.9 2 0 0 2 2 2 0 LETM1-like protein Exonuc_VII_L PF02601.15 PFH36678.1 - 0.25 10.9 6.1 0.2 11.2 4.4 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4094 PF13334.6 PFH36678.1 - 0.3 11.5 6.0 0.29 11.6 1.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Phage_GP20 PF06810.11 PFH36678.1 - 0.33 10.8 7.7 0.056 13.2 4.0 1.7 2 0 0 2 2 1 0 Phage minor structural protein GP20 FAM76 PF16046.5 PFH36678.1 - 0.38 10.1 5.8 0.69 9.2 5.8 1.4 1 0 0 1 1 1 0 FAM76 protein ADIP PF11559.8 PFH36678.1 - 0.6 10.2 13.9 0.07 13.2 8.8 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Laminin_I PF06008.14 PFH36678.1 - 0.77 9.4 14.6 0.54 9.9 8.5 2.1 2 0 0 2 2 2 0 Laminin Domain I Spc7 PF08317.11 PFH36678.1 - 1.4 7.8 14.9 0.52 9.1 11.6 1.9 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF3450 PF11932.8 PFH36678.1 - 1.7 7.9 10.3 0.31 10.3 6.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.15 PFH36678.1 - 1.8 8.4 14.4 1.4 8.7 1.7 2.9 2 1 1 3 3 3 0 Septum formation initiator Swi5 PF07061.11 PFH36678.1 - 2 8.6 10.8 1.7 8.7 5.4 3.0 3 1 1 4 4 3 0 Swi5 Prominin PF05478.11 PFH36678.1 - 2.9 5.7 7.5 3.5 5.5 4.5 1.9 2 0 0 2 2 2 0 Prominin Atg14 PF10186.9 PFH36678.1 - 3 6.8 10.2 0.38 9.8 5.9 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin_1 PF12718.7 PFH36678.1 - 3.1 7.9 15.2 0.66 10.1 10.1 2.2 2 1 0 2 2 2 0 Tropomyosin like CENP-H PF05837.12 PFH36678.1 - 3.3 8.2 11.8 0.86 10.0 7.8 2.1 2 1 0 2 2 2 0 Centromere protein H (CENP-H) CENP-F_leu_zip PF10473.9 PFH36678.1 - 3.3 7.7 15.0 0.12 12.3 6.8 2.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 PFH36678.1 - 4.3 8.0 12.4 0.54 10.9 4.9 2.6 2 1 1 3 3 2 0 SlyX Jnk-SapK_ap_N PF09744.9 PFH36678.1 - 5.8 7.1 18.5 0.079 13.2 6.9 2.8 2 2 0 2 2 2 0 JNK_SAPK-associated protein-1 YabA PF06156.13 PFH36678.1 - 6.5 7.5 10.7 3.2 8.4 5.8 2.4 2 1 0 2 2 2 0 Initiation control protein YabA DUF16 PF01519.16 PFH36678.1 - 6.8 7.2 11.0 11 6.5 8.1 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 BCAS2 PF05700.11 PFH36678.1 - 7.5 6.2 13.0 0.46 10.2 6.6 2.0 2 1 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) BRE1 PF08647.11 PFH36678.1 - 7.9 6.6 14.3 1.1 9.3 8.8 2.2 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase PPP4R2 PF09184.11 PFH36680.1 - 4.2e-08 33.1 0.3 4.2e-08 33.1 0.3 2.5 2 0 0 2 2 2 1 PPP4R2 Hexokinase_1 PF00349.21 PFH36681.1 - 3.8e-54 183.6 0.0 5.3e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 PFH36681.1 - 4e-49 167.2 0.2 6.1e-49 166.6 0.2 1.3 1 0 0 1 1 1 1 Hexokinase DUF1731 PF08338.11 PFH36681.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) PI3K_P85_iSH2 PF16454.5 PFH36682.1 - 0.0071 15.9 35.6 0.021 14.4 13.9 3.3 1 1 1 3 3 3 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Taxilin PF09728.9 PFH36682.1 - 0.016 14.4 30.9 0.32 10.1 9.2 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein TPR_MLP1_2 PF07926.12 PFH36682.1 - 0.3 11.2 45.6 0.99 9.5 17.1 3.8 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein HAP1_N PF04849.13 PFH36682.1 - 0.94 8.6 38.8 4 6.6 1.5 3.0 1 1 1 2 2 2 0 HAP1 N-terminal conserved region CENP-F_leu_zip PF10473.9 PFH36682.1 - 1.1 9.3 42.6 4 7.5 14.6 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 PFH36682.1 - 1.3 9.7 34.1 2.2 8.9 4.1 3.6 2 2 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 PFH36682.1 - 1.6 8.9 44.8 0.069 13.4 11.5 3.9 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 PFH36682.1 - 2.9 7.4 38.2 0.048 13.2 21.2 2.7 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Lectin_N PF03954.14 PFH36682.1 - 3.5 7.4 13.3 0.37 10.6 0.8 2.9 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain FUSC PF04632.12 PFH36682.1 - 4.5 5.7 16.6 0.38 9.2 5.0 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF812 PF05667.11 PFH36682.1 - 4.7 6.0 32.9 16 4.2 32.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Fez1 PF06818.15 PFH36682.1 - 5 7.5 34.2 3.1 8.2 10.5 2.2 1 1 1 2 2 2 0 Fez1 DUF4472 PF14739.6 PFH36682.1 - 6.7 7.5 29.2 0.039 14.7 10.5 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) NAD_binding_6 PF08030.12 PFH36682.1 - 7.7 6.6 8.0 19 5.4 8.0 1.8 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Voltage_CLC PF00654.20 PFH36685.1 - 1.1e-54 186.1 46.6 5e-22 78.6 6.5 4.0 4 0 0 4 4 4 3 Voltage gated chloride channel CBS PF00571.28 PFH36685.1 - 0.00062 20.2 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 CBS domain zf-ribbon_3 PF13248.6 PFH36686.1 - 0.0044 16.4 3.7 0.009 15.4 3.7 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 PFH36686.1 - 0.023 14.7 1.1 0.038 14.0 1.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.6 PFH36686.1 - 1.1 9.2 3.1 14 5.7 0.3 2.5 2 0 0 2 2 2 0 Nudix N-terminal RRM_1 PF00076.22 PFH36688.1 - 3.8e-29 100.3 1.6 5.2e-16 58.2 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH36688.1 - 2.4e-10 40.4 0.2 9.8e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 PFH36688.1 - 2.9e-05 24.0 1.1 0.16 12.0 0.1 2.6 1 1 1 2 2 2 2 RNA binding motif PHM7_cyt PF14703.6 PFH36688.1 - 0.031 14.5 3.3 0.17 12.1 0.0 2.7 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Peptidase_M14 PF00246.24 PFH36690.1 - 4.4e-11 43.1 0.0 8.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 PFH36690.1 - 1.3e-07 31.9 0.5 6.5e-07 29.7 0.1 2.0 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 PFH36690.1 - 2e-05 23.8 0.0 3.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Methyltransf_11 PF08241.12 PFH36692.1 - 1.4e-05 25.7 0.0 0.0065 17.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 PFH36692.1 - 0.00044 20.9 0.0 2.1 9.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Las1 PF04031.13 PFH36693.1 - 5.5e-33 114.3 0.1 5.7e-32 111.0 0.0 2.3 2 0 0 2 2 2 1 Las1-like PhoD PF09423.10 PFH36694.1 - 2.7e-15 56.3 1.9 8.1e-12 44.8 0.0 2.7 2 1 0 3 3 3 2 PhoD-like phosphatase Pkinase PF00069.25 PFH36695.1 - 1.9e-17 63.5 0.0 9.4e-17 61.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PFH36695.1 - 8.7e-17 61.3 0.1 2.5e-16 59.8 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH36695.1 - 0.00055 19.3 0.1 0.01 15.1 0.1 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 PFH36695.1 - 0.0013 18.1 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 PFH36695.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 AceK PF06315.11 PFH36695.1 - 0.16 10.4 0.0 0.27 9.7 0.0 1.3 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Kinase-like PF14531.6 PFH36696.1 - 2e-24 86.4 0.0 4.4e-24 85.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH36696.1 - 1.3e-17 64.0 0.0 2.6e-16 59.8 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36696.1 - 2.2e-05 23.9 0.0 5.6e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PFH36696.1 - 0.0011 17.8 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 PFH36696.1 - 0.013 15.2 0.9 0.018 14.7 0.1 1.6 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Haspin_kinase PF12330.8 PFH36696.1 - 0.021 13.8 0.1 0.048 12.6 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 PFH36696.1 - 0.039 13.3 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PFH36696.1 - 0.14 11.7 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HALZ PF02183.18 PFH36697.1 - 8 6.8 24.5 0.33 11.2 0.4 5.5 5 0 0 5 5 5 0 Homeobox associated leucine zipper RNase_Zc3h12a PF11977.8 PFH36698.1 - 3.8e-24 85.2 0.0 7.4e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain EST1 PF10374.9 PFH36698.1 - 0.00038 21.1 0.1 0.0011 19.6 0.1 1.9 1 0 0 1 1 1 1 Telomerase activating protein Est1 EST1_DNA_bind PF10373.9 PFH36698.1 - 0.11 12.0 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain UL42 PF17638.2 PFH36698.1 - 0.38 10.7 7.3 0.027 14.5 0.7 2.5 2 0 0 2 2 2 0 HCMV UL42 CN_hydrolase PF00795.22 PFH36699.1 - 7.1e-36 123.9 0.0 8.8e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Bacillus_HBL PF05791.11 PFH36699.1 - 0.19 11.5 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Pantoate_ligase PF02569.15 PFH36700.1 - 7.1e-59 199.2 0.0 2.2e-58 197.6 0.0 1.7 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Acetyltransf_1 PF00583.25 PFH36700.1 - 0.026 14.7 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PFH36700.1 - 0.06 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MPP6 PF10175.9 PFH36701.1 - 0.015 15.8 10.6 1.1 9.8 10.6 2.4 1 1 0 1 1 1 0 M-phase phosphoprotein 6 CDK2AP PF09806.9 PFH36701.1 - 1.5 8.9 8.0 11 6.0 5.5 2.2 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein Ndc1_Nup PF09531.10 PFH36701.1 - 3.4 6.2 7.4 4 6.0 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PI3_PI4_kinase PF00454.27 PFH36702.1 - 1.6e-22 80.5 0.0 1.6e-19 70.7 0.0 3.0 3 0 0 3 3 3 2 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 PFH36702.1 - 0.039 13.8 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 FATC domain PRP38 PF03371.15 PFH36703.1 - 4e-55 186.4 0.0 7e-55 185.6 0.0 1.4 1 0 0 1 1 1 1 PRP38 family RCC1 PF00415.18 PFH36704.1 - 1.3e-42 144.2 10.2 2.4e-11 44.0 0.1 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH36704.1 - 2.4e-18 65.4 21.1 5.7e-05 22.8 3.3 5.7 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Ribosomal_S2 PF00318.20 PFH36706.1 - 1.9e-30 105.7 0.7 2e-14 53.4 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 PFH36706.1 - 0.9 10.9 17.0 3.4 9.1 17.0 1.9 1 1 0 1 1 1 0 40S ribosomal protein SA C-terminus Ribosomal_L31e PF01198.19 PFH36708.1 - 6.3e-43 144.9 1.4 8e-43 144.6 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Prominin PF05478.11 PFH36709.1 - 0.4 8.6 4.3 0.55 8.1 4.3 1.1 1 0 0 1 1 1 0 Prominin TMEM43 PF07787.12 PFH36710.1 - 9.7e-19 67.7 0.0 1.4e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 43 Pkinase PF00069.25 PFH36711.1 - 6.6e-24 84.7 0.0 5.9e-23 81.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PFH36711.1 - 2.2e-16 60.1 0.0 3.4e-16 59.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH36711.1 - 5.4e-11 42.3 0.0 9.8e-09 34.9 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PFH36711.1 - 0.0052 16.7 0.0 0.0078 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PFH36711.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 PFH36711.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PFH36711.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family MIR PF02815.19 PFH36712.1 - 0.054 13.3 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 MIR domain DEAD PF00270.29 PFH36713.1 - 1.3e-32 113.0 0.0 2.3e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH36713.1 - 1.9e-29 102.2 0.0 5.3e-29 100.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH36713.1 - 0.00011 22.3 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PFH36713.1 - 0.045 14.0 0.0 0.21 11.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain FliT PF05400.13 PFH36713.1 - 0.3 11.9 7.9 0.19 12.5 0.5 3.0 2 0 0 2 2 2 0 Flagellar protein FliT GSHPx PF00255.19 PFH36714.1 - 7.1e-21 73.8 0.0 9.8e-21 73.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 PFH36714.1 - 0.0019 18.1 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family GSHPx PF00255.19 PFH36716.1 - 2.5e-30 104.2 0.1 3.6e-30 103.7 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 PFH36716.1 - 0.00044 20.1 0.0 0.00085 19.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PFH36716.1 - 0.048 13.4 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Redoxin GSHPx PF00255.19 PFH36717.1 - 9.7e-17 60.5 0.1 1.5e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione peroxidase Peptidase_M50 PF02163.22 PFH36718.1 - 0.26 10.5 11.2 4.1 6.6 0.8 3.0 1 1 1 2 2 2 0 Peptidase family M50 Acyl-CoA_dh_1 PF00441.24 PFH36720.1 - 1.7e-46 158.2 4.6 2.7e-46 157.5 4.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PFH36720.1 - 7.7e-30 103.9 0.0 4e-29 101.5 0.0 2.3 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PFH36720.1 - 3.8e-23 81.5 0.0 7.1e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PFH36720.1 - 2.4e-19 69.9 1.6 5.2e-19 68.8 1.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Adaptin_N PF01602.20 PFH36721.1 - 7.8e-87 292.0 0.0 1e-86 291.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 PFH36721.1 - 3.6e-31 108.4 2.4 1.2e-29 103.5 0.5 2.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PFH36721.1 - 2.6e-10 40.6 7.7 0.00037 20.8 0.1 5.3 4 1 1 5 5 5 3 HEAT repeats B2-adapt-app_C PF09066.10 PFH36721.1 - 1.1e-05 25.4 0.1 5.9e-05 23.1 0.1 2.1 1 1 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.22 PFH36721.1 - 0.00037 20.5 10.6 0.23 11.8 0.1 5.3 5 0 0 5 5 5 2 HEAT repeat RTP1_C1 PF10363.9 PFH36721.1 - 0.004 17.3 0.1 0.55 10.4 0.0 3.9 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 API5 PF05918.11 PFH36721.1 - 0.15 10.8 0.0 0.42 9.4 0.0 1.7 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) HEAT_EZ PF13513.6 PFH36721.1 - 0.22 12.1 4.1 5.1 7.7 0.1 4.2 4 0 0 4 4 4 0 HEAT-like repeat Sigma70_ner PF04546.13 PFH36722.1 - 0.3 11.0 2.9 5.8 6.7 0.2 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region GNT-I PF03071.15 PFH36723.1 - 1.1e-08 34.2 0.0 3e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 GNT-I family Gly_transf_sug PF04488.15 PFH36725.1 - 5e-06 27.1 0.0 9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 PFH36725.1 - 0.3 10.3 0.0 0.54 9.5 0.0 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Gly_transf_sug PF04488.15 PFH36726.1 - 0.00061 20.4 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Serglycin PF04360.12 PFH36741.1 - 1.1 9.2 5.3 1.8 8.5 5.3 1.3 1 0 0 1 1 1 0 Serglycin BT1 PF03092.16 PFH36746.1 - 1.2e-80 271.2 24.4 5.8e-59 199.7 10.4 2.1 2 0 0 2 2 2 2 BT1 family DUF5117 PF17148.4 PFH36746.1 - 0.26 11.1 0.0 0.42 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5117) FtsL PF04999.13 PFH36746.1 - 0.9 9.6 3.3 0.59 10.2 0.7 1.9 2 0 0 2 2 2 0 Cell division protein FtsL DUF2070 PF09843.9 PFH36746.1 - 3.4 5.8 8.7 6.4 4.9 8.7 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF501 PF04417.12 PFH36747.1 - 1.3 8.8 3.5 1 9.1 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF501) Pex19 PF04614.12 PFH36748.1 - 0.0025 17.6 20.2 0.0035 17.1 0.0 4.7 3 1 1 4 4 4 2 Pex19 protein family Macoilin PF09726.9 PFH36748.1 - 0.5 8.9 5.1 1.2 7.7 5.1 1.6 1 0 0 1 1 1 0 Macoilin family Mlh1_C PF16413.5 PFH36749.1 - 2.6e-41 141.8 0.0 5.6e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 PFH36749.1 - 1.2e-19 70.1 0.0 2.3e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 PFH36749.1 - 6.1e-10 39.1 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PFH36749.1 - 7.7e-06 26.4 0.0 1.7e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PUF PF00806.19 PFH36750.1 - 4.7e-10 38.6 0.0 0.043 13.5 0.0 5.5 6 0 0 6 6 6 3 Pumilio-family RNA binding repeat DUF1242 PF06842.12 PFH36751.1 - 0.23 11.3 0.1 0.49 10.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) DnaB PF00772.21 PFH36752.1 - 0.0084 16.2 0.2 0.087 12.9 0.0 2.8 2 0 0 2 2 2 1 DnaB-like helicase N terminal domain Lysine_decarbox PF03641.14 PFH36753.1 - 5.3e-26 91.3 0.0 8e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 PFH36753.1 - 4.4e-07 29.6 0.0 8.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 SLOG cluster4 family Methyltrn_RNA_4 PF09936.9 PFH36753.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase Rad60-SLD PF11976.8 PFH36754.1 - 6.3e-24 83.6 0.1 7.4e-24 83.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 PFH36754.1 - 1.4e-11 44.0 0.0 1.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family UBX PF00789.20 PFH36754.1 - 0.032 14.4 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 UBX domain SRP9-21 PF05486.12 PFH36754.1 - 0.034 14.5 0.1 0.041 14.3 0.1 1.1 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) HJURP_C PF12347.8 PFH36754.1 - 0.12 12.5 0.2 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat OTU PF02338.19 PFH36757.1 - 5.6e-06 26.9 0.0 8.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease Thioredoxin PF00085.20 PFH36758.1 - 2e-15 56.6 0.1 4.1e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 PFH36758.1 - 0.00037 20.7 0.2 0.0069 16.7 0.0 2.8 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 PFH36758.1 - 0.0028 17.8 0.1 0.0055 16.9 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 PFH36758.1 - 0.19 11.1 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Ank_5 PF13857.6 PFH36759.1 - 0.0074 16.6 0.0 0.028 14.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) AMP-binding PF00501.28 PFH36760.1 - 2.6e-91 306.3 0.0 3.2e-91 306.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PFH36760.1 - 6.3e-26 91.2 1.4 7.7e-25 87.7 1.2 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 PFH36760.1 - 1.6e-18 66.4 1.3 4e-18 65.1 1.3 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF3540 PF12059.8 PFH36762.1 - 0.14 12.0 22.9 0.059 13.2 2.9 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3540) LUC7 PF03194.15 PFH36762.1 - 1.3 8.6 27.5 0.3 10.7 5.8 3.1 2 1 1 3 3 3 0 LUC7 N_terminus Tropomyosin PF00261.20 PFH36762.1 - 1.7 8.0 40.5 0.01 15.2 7.3 3.5 2 1 1 3 3 3 0 Tropomyosin RNA_pol_Rpc4 PF05132.14 PFH36764.1 - 7.5e-29 101.1 1.5 1.7e-28 99.9 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase III RPC4 DUF2749 PF10907.8 PFH36764.1 - 0.088 13.0 3.9 0.87 9.8 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) FAM184 PF15665.5 PFH36765.1 - 0.067 13.0 15.7 0.14 11.9 15.7 1.5 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B UPF0242 PF06785.11 PFH36765.1 - 1.8 8.6 12.4 3.2 7.8 12.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Pkinase PF00069.25 PFH36767.1 - 6.5e-59 199.4 0.0 1.3e-57 195.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36767.1 - 1.8e-36 125.8 0.0 2.4e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH36767.1 - 4.1e-09 36.2 0.0 2.4e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PFH36767.1 - 4.2e-05 22.5 0.1 0.0001 21.3 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase tRNA-synt_1 PF00133.22 PFH36768.1 - 2.4e-32 112.0 1.5 1.8e-12 46.3 0.1 5.6 5 1 1 6 6 6 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PFH36768.1 - 8.7e-21 74.1 0.0 2.6e-08 33.0 0.0 3.6 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 PFH36768.1 - 4.2e-10 39.8 0.0 8.5e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 PFH36768.1 - 3.7e-07 29.9 0.0 3e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.18 PFH36768.1 - 0.0061 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 PFH36768.1 - 0.064 12.6 0.0 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain RRM_1 PF00076.22 PFH36769.1 - 4.4e-38 128.9 0.0 1.2e-17 63.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PFH36769.1 - 1.7e-07 31.2 0.0 0.00018 21.4 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 PFH36769.1 - 0.0031 17.5 0.0 0.41 10.8 0.1 2.5 2 0 0 2 2 2 1 Limkain b1 RRM_3 PF08777.11 PFH36769.1 - 0.0052 16.8 0.0 0.66 10.1 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif LAL_C2 PF18603.1 PFH36770.1 - 0.041 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 EamA PF00892.20 PFH36771.1 - 2.5e-08 34.2 19.1 1e-06 29.0 1.3 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PFH36771.1 - 4.2e-08 32.8 14.1 6.7e-08 32.1 14.1 1.3 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 PFH36771.1 - 2.3e-06 27.0 1.5 2.3e-06 27.0 1.5 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.16 PFH36771.1 - 3.2e-06 26.7 6.9 4e-06 26.4 6.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 PFH36771.1 - 2.6e-05 23.6 3.0 2.6e-05 23.6 3.0 1.7 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 PFH36771.1 - 0.00077 18.5 1.6 0.00077 18.5 1.6 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like DUF1129 PF06570.11 PFH36771.1 - 0.057 12.9 3.7 0.13 11.7 3.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) HlyIII PF03006.20 PFH36771.1 - 0.36 10.5 18.6 0.65 9.7 9.8 2.6 1 1 1 2 2 2 0 Haemolysin-III related Iso_dh PF00180.20 PFH36772.1 - 7.9e-72 242.3 0.0 9.1e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PUA_3 PF17785.1 PFH36772.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 PUA-like domain CPW_WPC PF09717.10 PFH36773.1 - 5.3e-29 101.0 8.7 1.3e-15 58.1 1.2 2.3 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) Defensin_int PF17858.1 PFH36773.1 - 0.2 11.7 2.0 0.6 10.1 2.0 1.8 1 0 0 1 1 1 0 Platypus intermediate defensin-like peptide Pkinase PF00069.25 PFH36774.1 - 5.3e-12 45.6 0.0 2.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36774.1 - 5.4e-11 42.3 0.0 0.00012 21.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase zf_CCCH_4 PF18345.1 PFH36774.1 - 0.0035 17.3 2.5 0.0035 17.3 2.5 3.5 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 PFH36774.1 - 0.0064 16.3 1.1 0.0064 16.3 1.1 2.8 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 PFH36774.1 - 0.29 11.1 16.1 0.018 14.9 1.4 3.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) VIT1 PF01988.19 PFH36775.1 - 8.7e-57 192.4 3.9 1.1e-56 192.1 3.9 1.1 1 0 0 1 1 1 1 VIT family TMEM65 PF10507.9 PFH36775.1 - 0.0021 18.0 0.1 0.005 16.8 0.1 1.8 1 0 0 1 1 1 1 Transmembrane protein 65 Sec7 PF01369.20 PFH36777.1 - 2.9e-42 144.4 0.0 4.9e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain RabGAP-TBC PF00566.18 PFH36777.1 - 4.3e-31 108.3 0.6 8e-31 107.4 0.6 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Methyltransf_23 PF13489.6 PFH36779.1 - 2.2e-21 76.4 0.0 2.9e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PFH36779.1 - 8.3e-13 48.4 0.0 4.5e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PFH36779.1 - 1e-12 48.5 0.1 1.2e-11 45.0 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH36779.1 - 6.4e-11 42.9 0.0 1.3e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH36779.1 - 7.3e-11 42.6 0.1 1e-09 38.9 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 PFH36779.1 - 2.9e-06 27.1 0.0 4.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 PFH36779.1 - 2.7e-05 23.6 0.0 0.0085 15.4 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase PrmA PF06325.13 PFH36779.1 - 5.6e-05 22.7 0.0 0.00013 21.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PFH36779.1 - 0.00011 21.8 0.0 0.00051 19.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 PFH36779.1 - 0.00042 20.3 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PFH36779.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Sterol_MT_C PF08498.10 PFH36779.1 - 0.017 15.4 0.2 3.7 7.9 0.0 2.4 1 1 1 2 2 2 0 Sterol methyltransferase C-terminal NodS PF05401.11 PFH36779.1 - 0.028 14.1 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 PFH36779.1 - 0.095 11.6 0.0 0.21 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) MetW PF07021.12 PFH36779.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.5 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.13 PFH36779.1 - 0.18 12.1 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase BTB PF00651.31 PFH36780.1 - 1.2e-17 64.1 0.2 3e-17 62.8 0.2 1.7 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 PFH36781.1 - 3.6e-15 55.8 36.3 1.4e-14 53.8 36.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4027 PF13219.6 PFH36781.1 - 7.4 6.5 8.0 26 4.8 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4027) Dus PF01207.17 PFH36782.1 - 2.8e-57 194.2 0.0 7e-56 189.6 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF2102 PF09875.9 PFH36782.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) DUF1768 PF08719.11 PFH36783.1 - 0.00046 20.5 0.1 0.0021 18.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) PI3K_C2 PF00792.24 PFH36783.1 - 0.031 14.2 0.9 0.053 13.4 0.0 1.8 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 HEPN_Swt1 PF18731.1 PFH36783.1 - 0.046 14.1 6.8 0.087 13.2 4.9 2.3 2 0 0 2 2 2 0 Swt1-like HEPN hDGE_amylase PF14701.6 PFH36783.1 - 0.76 8.8 9.3 1.5 7.8 9.3 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Cyclin_N PF00134.23 PFH36784.1 - 4.2e-08 33.0 0.0 6.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 PFH36784.1 - 6.8e-08 33.1 0.0 8.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin PDEase_I PF00233.19 PFH36785.1 - 7.3e-66 222.3 0.7 1.3e-65 221.5 0.7 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 PFH36785.1 - 0.004 17.4 0.1 0.01 16.0 0.1 1.6 1 0 0 1 1 1 1 HD domain Tfb4 PF03850.14 PFH36786.1 - 1.4e-32 113.3 2.1 2.6e-32 112.4 2.1 1.4 1 0 0 1 1 1 1 Transcription factor Tfb4 DHHC PF01529.20 PFH36787.1 - 4.1e-27 94.9 16.9 6.9e-27 94.2 5.3 3.3 4 0 0 4 4 4 2 DHHC palmitoyltransferase DUF35_N PF12172.8 PFH36787.1 - 9.7 6.2 19.0 2.2 8.3 11.0 3.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pkinase PF00069.25 PFH36788.1 - 5.3e-38 130.9 0.0 7.9e-32 110.7 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36788.1 - 1.3e-14 54.1 0.0 8.2e-14 51.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH36788.1 - 0.0037 16.6 0.0 0.0079 15.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Tubulin PF00091.25 PFH36790.1 - 5.8e-69 232.2 0.0 1.3e-68 231.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PFH36790.1 - 1.1e-41 141.9 0.1 1.6e-41 141.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PFH36790.1 - 0.00068 19.9 0.0 0.0019 18.5 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 PFH36790.1 - 0.0041 16.3 0.0 0.019 14.1 0.0 1.9 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 PFH36790.1 - 0.0073 16.0 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain ubiquitin PF00240.23 PFH36791.1 - 3.1e-07 30.0 0.9 2.7e-05 23.8 0.0 3.7 3 1 1 4 4 4 1 Ubiquitin family Adaptin_N PF01602.20 PFH36792.1 - 1.4e-74 251.6 0.7 2.3e-74 250.8 0.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 PFH36792.1 - 5.3e-42 142.8 0.3 9.7e-20 70.9 0.0 2.8 3 0 0 3 3 3 2 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 PFH36792.1 - 1.1e-39 135.6 0.0 2.2e-39 134.5 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 PFH36792.1 - 3.3e-08 33.7 3.0 4e-05 23.7 0.1 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PFH36792.1 - 0.00018 21.9 3.4 0.0076 16.6 0.0 4.2 3 2 0 4 4 4 1 HEAT repeats RTP1_C1 PF10363.9 PFH36792.1 - 0.00031 20.9 2.7 0.0079 16.4 0.0 3.9 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 PFH36792.1 - 0.00032 20.7 0.3 0.013 15.7 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat PDZ_6 PF17820.1 PFH36793.1 - 0.00011 22.0 0.2 0.00034 20.4 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PFH36793.1 - 0.016 15.5 0.0 0.044 14.1 0.0 1.6 2 0 0 2 2 2 0 PDZ domain TPR_16 PF13432.6 PFH36793.1 - 0.018 15.7 0.8 0.018 15.7 0.8 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 PFH36793.1 - 0.021 14.7 0.0 0.048 13.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat PDZ PF00595.24 PFH36793.1 - 0.063 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Ant_C PF05586.11 PFH36793.1 - 0.082 13.5 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 Anthrax receptor C-terminus region ChAPs PF09295.10 PFH36793.1 - 0.083 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 PFH36793.1 - 0.096 12.8 0.4 0.5 10.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3046 PF11248.8 PFH36794.1 - 0.073 13.4 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) MerC PF03203.14 PFH36795.1 - 0.0023 18.4 0.0 0.0034 17.8 0.0 1.2 1 0 0 1 1 1 1 MerC mercury resistance protein CAF1 PF04857.20 PFH36795.1 - 0.54 9.4 4.9 0.81 8.8 4.9 1.4 1 0 0 1 1 1 0 CAF1 family ribonuclease eIF-3c_N PF05470.12 PFH36795.1 - 4.4 5.5 13.4 9.4 4.4 13.4 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ras PF00071.22 PFH36797.1 - 4.7e-33 114.1 0.0 6e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH36797.1 - 7e-18 65.0 0.0 1.1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH36797.1 - 1.8e-08 34.0 0.0 2.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PFH36797.1 - 0.00039 20.5 0.0 0.00061 19.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PFH36797.1 - 0.0018 17.8 0.0 0.067 12.7 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PFH36797.1 - 0.006 16.5 0.0 0.74 9.7 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 PFH36797.1 - 0.006 16.8 0.1 0.015 15.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 PFH36797.1 - 0.0061 17.1 0.0 0.0078 16.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.12 PFH36797.1 - 0.012 14.9 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NACHT PF05729.12 PFH36797.1 - 0.033 14.1 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 PFH36797.1 - 0.04 14.3 0.1 0.12 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 PFH36797.1 - 0.048 13.1 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 PFH36797.1 - 0.058 13.1 0.1 1.2 8.8 0.1 2.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 PFH36797.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DLIC PF05783.11 PFH36797.1 - 0.084 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Septin PF00735.18 PFH36797.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_5 PF07728.14 PFH36797.1 - 0.18 11.8 0.0 13 5.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PFH36797.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 PFH36797.1 - 0.2 11.7 0.1 1 9.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain Hydrolase_4 PF12146.8 PFH36798.1 - 1.2e-06 28.0 0.3 5.5e-06 25.8 0.3 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PFH36798.1 - 1.8e-06 27.6 0.0 3.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 PFH36798.1 - 6.8e-06 25.9 0.3 0.00011 21.9 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 PFH36798.1 - 0.00012 22.1 0.1 0.0007 19.6 0.1 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 PFH36798.1 - 0.00016 22.4 0.0 0.00032 21.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 PFH36798.1 - 0.0043 16.7 0.0 0.0087 15.7 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 PFH36798.1 - 0.0045 17.1 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.18 PFH36798.1 - 0.0065 16.0 0.2 0.013 15.0 0.1 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 PFH36798.1 - 0.0095 15.6 0.1 0.015 15.0 0.1 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 PFH36798.1 - 0.05 13.4 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 PFH36798.1 - 0.076 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ribosomal_L14e PF01929.17 PFH36799.1 - 2.5e-28 98.4 5.3 3.3e-28 98.0 5.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 PFH36799.1 - 0.027 14.4 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 KOW motif OB_RNB PF08206.11 PFH36799.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain MIP PF00230.20 PFH36800.1 - 2.5e-11 43.8 31.6 7.4e-07 29.1 10.0 3.0 1 1 0 2 2 2 2 Major intrinsic protein CrgA PF06781.12 PFH36800.1 - 3.2 7.9 4.3 1.2 9.3 0.2 2.5 3 0 0 3 3 3 0 Cell division protein CrgA AAA PF00004.29 PFH36801.1 - 4.3e-43 146.9 0.0 9.5e-43 145.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PFH36801.1 - 1.4e-09 37.6 0.6 2.9e-09 36.6 0.6 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 PFH36801.1 - 1.2e-08 34.8 0.0 2.5e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 PFH36801.1 - 2.1e-06 28.0 0.0 5.8e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PFH36801.1 - 3.5e-06 27.3 0.1 0.0033 17.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PFH36801.1 - 2.4e-05 24.2 0.0 5.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PFH36801.1 - 3.8e-05 24.1 0.1 0.0016 18.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 PFH36801.1 - 3.9e-05 22.9 0.0 6.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 PFH36801.1 - 4e-05 23.6 0.4 0.00023 21.2 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 PFH36801.1 - 0.0012 18.7 0.1 0.0067 16.2 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 PFH36801.1 - 0.002 18.2 0.0 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PFH36801.1 - 0.0025 18.4 0.1 0.0093 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PFH36801.1 - 0.0044 17.2 0.0 0.014 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 PFH36801.1 - 0.0062 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 PFH36801.1 - 0.0064 16.8 0.2 0.018 15.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 PFH36801.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 PFH36801.1 - 0.016 15.6 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 PFH36801.1 - 0.02 14.8 0.1 0.098 12.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 PFH36801.1 - 0.024 13.8 0.0 0.47 9.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 PFH36801.1 - 0.031 14.0 0.2 0.081 12.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 PFH36801.1 - 0.034 13.6 0.2 0.14 11.6 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 PFH36801.1 - 0.06 13.3 0.0 0.47 10.3 0.0 2.1 1 1 1 2 2 2 0 NACHT domain NTPase_1 PF03266.15 PFH36801.1 - 0.06 13.3 0.1 0.6 10.0 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 PFH36801.1 - 0.062 13.0 0.1 0.19 11.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PFH36801.1 - 0.065 12.7 0.0 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 PFH36801.1 - 0.067 12.5 0.1 0.61 9.4 0.1 2.2 1 1 0 2 2 2 0 KaiC ATPase_2 PF01637.18 PFH36801.1 - 0.067 13.1 0.4 1.9 8.3 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 PFH36801.1 - 0.094 12.3 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 PFH36801.1 - 0.14 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 PFH36801.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SAG PF04092.13 PFH36802.1 - 4.8e-15 56.5 12.3 2.7e-07 31.4 0.7 3.8 3 1 1 4 4 4 4 SRS domain SAG PF04092.13 PFH36803.1 - 1.9e-38 132.2 19.7 1.1e-19 71.5 3.0 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36804.1 - 2.1e-36 125.6 22.7 3.8e-20 73.0 4.8 2.2 2 0 0 2 2 2 2 SRS domain Pilin PF00114.19 PFH36804.1 - 0.035 15.0 3.5 0.035 15.0 3.5 2.2 2 1 0 3 3 3 0 Pilin (bacterial filament) CVNH PF08881.10 PFH36804.1 - 0.038 14.7 0.5 0.11 13.2 0.1 1.9 2 0 0 2 2 2 0 CVNH domain SAG PF04092.13 PFH36805.1 - 3.4e-38 131.4 14.9 7e-21 75.4 3.9 2.1 2 0 0 2 2 2 2 SRS domain Pilin PF00114.19 PFH36805.1 - 0.02 15.8 6.6 0.036 15.0 3.5 2.4 1 1 0 2 2 2 0 Pilin (bacterial filament) SAG PF04092.13 PFH36806.1 - 8.8e-36 123.6 22.0 8.8e-21 75.1 4.0 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36807.1 - 6.4e-41 140.2 16.9 3e-20 73.4 4.9 2.1 2 0 0 2 2 2 2 SRS domain Pilin PF00114.19 PFH36807.1 - 0.019 15.9 3.2 0.019 15.9 3.2 2.2 2 1 0 3 3 3 0 Pilin (bacterial filament) Phlebovirus_G2 PF07245.11 PFH36807.1 - 0.11 11.0 6.2 0.12 10.9 1.6 2.1 2 0 0 2 2 2 0 Phlebovirus glycoprotein G2 SAG PF04092.13 PFH36808.1 - 3.7e-27 95.7 4.9 6.6e-20 72.2 1.3 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36809.1 - 4.1e-37 127.9 16.8 3.9e-20 73.0 2.4 2.1 2 0 0 2 2 2 2 SRS domain Pilin PF00114.19 PFH36809.1 - 0.023 15.6 3.4 0.023 15.6 3.4 2.1 1 1 1 2 2 2 0 Pilin (bacterial filament) Cathelicidins PF00666.17 PFH36809.1 - 0.74 10.1 6.4 3.7 7.9 1.2 3.1 3 0 0 3 3 3 0 Cathelicidin SAG PF04092.13 PFH36810.1 - 4.8e-38 130.9 21.1 7.8e-21 75.2 4.6 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36811.1 - 1.3e-35 123.0 15.8 3e-18 66.9 2.6 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36812.1 - 2.4e-33 115.7 9.5 1.7e-19 70.9 3.0 2.0 2 0 0 2 2 2 2 SRS domain CUE PF02845.16 PFH36812.1 - 0.082 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 CUE domain SAG PF04092.13 PFH36813.1 - 1.4e-37 129.4 9.6 1.2e-18 68.1 1.3 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36814.1 - 3.4e-39 134.6 23.8 1.4e-21 77.6 1.2 2.5 3 0 0 3 3 3 2 SRS domain SH3_9 PF14604.6 PFH36814.1 - 0.045 13.6 0.3 0.1 12.5 0.3 1.6 1 0 0 1 1 1 0 Variant SH3 domain SAG PF04092.13 PFH36815.1 - 1.6e-05 25.7 0.0 2.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH36816.1 - 1.4e-30 106.8 4.3 3.3e-21 76.5 1.4 2.1 2 0 0 2 2 2 2 SRS domain DUF3564 PF12087.8 PFH36816.1 - 0.058 13.3 0.1 1.3 8.9 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3564) SCP2_2 PF13530.6 PFH36816.1 - 0.06 13.8 0.0 0.82 10.1 0.0 2.2 2 0 0 2 2 2 0 Sterol carrier protein domain SAG PF04092.13 PFH36817.1 - 4.1e-41 140.9 15.1 1.4e-21 77.6 0.7 2.2 2 0 0 2 2 2 2 SRS domain E1_DerP2_DerF2 PF02221.15 PFH36817.1 - 0.091 13.2 3.4 0.96 9.9 0.2 3.1 3 0 0 3 3 3 0 ML domain DUF3352 PF11832.8 PFH36817.1 - 0.19 10.4 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) SAG PF04092.13 PFH36818.1 - 2.8e-14 54.0 0.2 3e-14 53.9 0.2 1.0 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH36819.1 - 5e-38 130.9 14.5 5.6e-21 75.7 0.3 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36820.1 - 2.5e-44 151.2 10.6 1.5e-23 84.0 2.2 2.4 2 1 0 2 2 2 2 SRS domain SCP2_2 PF13530.6 PFH36820.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 Sterol carrier protein domain Tom37 PF10568.9 PFH36821.1 - 5.8e-07 29.9 0.1 1.3e-06 28.8 0.1 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAG PF04092.13 PFH36822.1 - 1.2e-39 136.1 18.0 9.5e-20 71.7 0.5 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36823.1 - 2.7e-42 144.7 14.3 1e-22 81.3 1.2 2.1 2 0 0 2 2 2 2 SRS domain Pilin PF00114.19 PFH36823.1 - 1 10.3 6.7 0.36 11.8 2.8 2.3 1 1 0 2 2 2 0 Pilin (bacterial filament) SAG PF04092.13 PFH36825.1 - 6.8e-33 114.2 9.3 3.1e-22 79.7 2.4 2.1 2 0 0 2 2 2 2 SRS domain PP2C PF00481.21 PFH36826.1 - 1.5e-66 224.6 0.0 1.9e-54 185.0 0.0 3.2 3 0 0 3 3 3 3 Protein phosphatase 2C PP2C_2 PF13672.6 PFH36826.1 - 0.00048 19.8 0.1 0.025 14.2 0.0 2.5 2 0 0 2 2 2 1 Protein phosphatase 2C Thx PF17070.5 PFH36826.1 - 0.53 10.5 2.9 1.3 9.2 2.9 1.7 1 0 0 1 1 1 0 30S ribosomal protein Thx SAG PF04092.13 PFH36828.1 - 6e-44 150.0 15.3 2.3e-23 83.4 2.0 2.1 2 0 0 2 2 2 2 SRS domain Pilin PF00114.19 PFH36828.1 - 0.00019 22.3 3.1 0.0012 19.7 0.2 2.7 3 0 0 3 3 3 1 Pilin (bacterial filament) SAG PF04092.13 PFH36829.1 - 1.6e-44 151.9 20.3 1.5e-23 84.1 2.3 2.5 3 0 0 3 3 3 2 SRS domain Pilin PF00114.19 PFH36829.1 - 7.9e-05 23.5 3.3 0.0013 19.6 0.2 3.0 3 0 0 3 3 3 1 Pilin (bacterial filament) SAG PF04092.13 PFH36830.1 - 1.7e-42 145.3 16.1 1.9e-23 83.7 3.2 2.2 2 0 0 2 2 2 2 SRS domain Pilin PF00114.19 PFH36830.1 - 9.8e-05 23.2 3.3 0.0006 20.7 0.2 2.8 3 0 0 3 3 3 1 Pilin (bacterial filament) SAG PF04092.13 PFH36831.1 - 2.1e-40 138.5 17.6 2.9e-23 83.1 2.4 2.2 2 0 0 2 2 2 2 SRS domain Pilin PF00114.19 PFH36831.1 - 0.0079 17.1 0.3 0.0079 17.1 0.3 2.9 2 1 1 3 3 3 1 Pilin (bacterial filament) SAG PF04092.13 PFH36832.1 - 1.3e-09 39.0 0.0 1.6e-09 38.6 0.0 1.1 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH36833.1 - 2.2e-22 80.2 2.6 2.9e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 SRS domain Etmic-2 PF06670.11 PFH36833.1 - 0.017 14.0 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Microneme protein Etmic-2 SAG PF04092.13 PFH36834.1 - 1.5e-33 116.4 0.8 9e-16 58.9 0.0 2.0 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36835.1 - 1.3e-42 145.7 17.1 1.1e-23 84.4 1.4 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36836.1 - 1.9e-41 141.9 24.5 1.6e-21 77.5 2.1 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36837.1 - 2.2e-38 132.0 18.8 1.2e-23 84.3 1.4 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36838.1 - 2e-42 145.1 20.1 3.8e-22 79.5 1.6 2.1 2 0 0 2 2 2 2 SRS domain EGF_3 PF12947.7 PFH36838.1 - 3.3 8.0 9.3 0.93 9.7 2.7 2.7 2 0 0 2 2 2 0 EGF domain SAG PF04092.13 PFH36839.1 - 4.3e-42 144.0 14.8 1.3e-23 84.2 1.5 2.1 2 0 0 2 2 2 2 SRS domain Entericidin PF08085.11 PFH36839.1 - 0.03 14.3 0.1 0.073 13.1 0.1 1.7 1 0 0 1 1 1 0 Entericidin EcnA/B family Nramp PF01566.18 PFH36840.1 - 2.4e-93 313.0 22.9 4.3e-93 312.1 22.9 1.4 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Jagunal PF07086.12 PFH36840.1 - 0.7 9.9 2.8 1.7 8.7 2.8 1.6 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis COPI_assoc PF08507.10 PFH36842.1 - 3.9e-11 43.1 4.7 6.2e-11 42.5 4.7 1.3 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 PFH36842.1 - 0.014 15.7 6.7 0.021 15.1 6.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Collectrin PF16959.5 PFH36842.1 - 0.11 12.2 0.2 0.23 11.2 0.2 1.4 1 0 0 1 1 1 0 Renal amino acid transporter FliD_C PF07195.12 PFH36843.1 - 0.39 10.1 23.5 0.28 10.6 3.2 4.0 4 0 0 4 4 4 0 Flagellar hook-associated protein 2 C-terminus Fumerase_C PF05683.12 PFH36844.1 - 1.1e-86 289.5 0.0 1.5e-86 289.0 0.0 1.2 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 PFH36844.1 - 1.7e-84 283.5 0.0 2.2e-84 283.1 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) DUF1389 PF07146.11 PFH36844.1 - 0.018 14.3 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) LSM PF01423.22 PFH36846.1 - 1.8e-17 62.7 1.3 2.4e-17 62.4 1.3 1.2 1 0 0 1 1 1 1 LSM domain SIR2 PF02146.17 PFH36847.1 - 3.4e-15 56.4 0.0 3.6e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 Sir2 family Kinesin PF00225.23 PFH36848.1 - 2.6e-28 98.9 0.0 1.8e-27 96.1 0.0 2.0 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PFH36848.1 - 1.7e-07 31.3 0.1 1.1e-06 28.7 0.0 2.2 3 0 0 3 3 3 1 Microtubule binding Nuc_sug_transp PF04142.15 PFH36849.1 - 6.3e-106 354.1 11.5 7.3e-106 353.9 11.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 PFH36849.1 - 9.3e-06 25.1 1.2 9.3e-06 25.1 1.2 2.3 3 0 0 3 3 3 1 UAA transporter family CRT-like PF08627.10 PFH36849.1 - 0.00014 20.9 4.6 0.00026 20.0 4.6 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 PFH36849.1 - 0.0048 17.1 10.0 0.0048 17.1 10.0 2.9 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 PFH36849.1 - 0.83 8.9 12.9 0.1 11.9 7.3 2.3 2 1 0 2 2 2 0 Triose-phosphate Transporter family RNA_pol_A_bac PF01000.26 PFH36850.1 - 1.1e-28 99.8 0.0 2e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 PFH36850.1 - 2e-20 72.0 0.0 2.7e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 PFH36850.1 - 0.0014 18.7 1.5 0.0038 17.4 1.5 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 PFH36850.1 - 0.089 13.4 1.9 0.2 12.3 1.9 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Ribosomal_L32e PF01655.18 PFH36851.1 - 2.3e-48 163.1 0.1 2.8e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 pKID PF02173.17 PFH36851.1 - 0.045 13.2 0.3 0.35 10.4 0.7 2.1 2 0 0 2 2 2 0 pKID domain LCCL PF03815.19 PFH36852.1 - 1.1e-78 259.4 3.1 7.5e-24 83.7 0.1 4.4 4 0 0 4 4 4 4 LCCL domain Mago_nashi PF02792.14 PFH36852.1 - 1.2e-73 245.9 0.7 2e-73 245.2 0.7 1.3 1 0 0 1 1 1 1 Mago nashi protein SRCR PF00530.18 PFH36852.1 - 2.4e-14 53.6 2.1 2.4e-14 53.6 2.1 2.9 2 1 0 2 2 2 1 Scavenger receptor cysteine-rich domain Rxt3 PF08642.10 PFH36852.1 - 5.9e-14 52.9 0.0 0.0022 18.8 0.0 3.6 3 0 0 3 3 3 3 Histone deacetylation protein Rxt3 PLAT PF01477.23 PFH36852.1 - 7.3e-14 52.3 0.0 3.1e-11 43.8 0.0 2.9 3 0 0 3 3 3 1 PLAT/LH2 domain Laminin_G_3 PF13385.6 PFH36852.1 - 5.2e-11 42.9 0.0 1.5e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.17 PFH36852.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Pentaxin family DnaJ PF00226.31 PFH36853.1 - 7.4e-14 51.6 0.2 5.4e-13 48.9 0.2 2.2 1 1 0 1 1 1 1 DnaJ domain zf-C3HC4_3 PF13920.6 PFH36854.1 - 3e-16 59.0 12.1 5.7e-16 58.1 12.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PFH36854.1 - 4.1e-08 33.0 11.7 9.9e-08 31.7 11.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PFH36854.1 - 1.5e-05 25.2 13.0 3.6e-05 24.0 13.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-P11 PF03854.14 PFH36854.1 - 0.00013 21.5 7.8 0.00024 20.7 7.8 1.4 1 0 0 1 1 1 1 P-11 zinc finger zf-RING_5 PF14634.6 PFH36854.1 - 0.014 15.3 12.1 0.036 14.0 12.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 PFH36854.1 - 0.42 10.4 4.0 0.83 9.5 1.0 2.8 3 0 0 3 3 3 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 PFH36854.1 - 0.49 10.3 15.6 0.28 11.1 12.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PFH36854.1 - 1.2 8.9 9.7 2.7 7.8 9.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RecR PF02132.15 PFH36854.1 - 3.9 7.1 12.2 3.8 7.2 6.7 2.3 2 0 0 2 2 2 0 RecR protein TSP_1 PF00090.19 PFH36855.1 - 0.00031 20.9 5.3 0.001 19.3 5.3 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain RCC1_2 PF13540.6 PFH36855.1 - 0.0037 17.0 19.5 1.3 8.9 0.0 6.4 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat AP2 PF00847.20 PFH36856.1 - 3.4e-13 49.6 0.9 7.1e-13 48.6 0.9 1.5 1 0 0 1 1 1 1 AP2 domain CSD PF00313.22 PFH36857.1 - 7.1e-25 86.6 0.1 1.1e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 PFH36857.1 - 0.0032 17.1 0.0 0.0069 16.0 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain TRM PF02005.16 PFH36858.1 - 2.5e-104 349.5 0.0 9.4e-78 262.0 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Peptidase_C1 PF00112.23 PFH36859.1 - 8.3e-17 62.0 0.1 1.6e-16 61.1 0.1 1.4 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.11 PFH36859.1 - 1.2e-05 25.5 0.1 0.00046 20.4 0.1 2.4 1 1 0 1 1 1 1 Cathepsin C exclusion domain DUF1648 PF07853.11 PFH36860.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) Vma12 PF11712.8 PFH36861.1 - 3.2e-05 24.0 0.0 6.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase MFS_1 PF07690.16 PFH36861.1 - 0.026 13.5 0.5 0.035 13.0 0.5 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF456 PF04306.13 PFH36861.1 - 0.055 13.8 0.3 0.1 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF5367 PF17329.2 PFH36861.1 - 0.067 13.3 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5367) zf-ANAPC11 PF12861.7 PFH36862.1 - 9e-22 77.0 6.8 1.1e-21 76.6 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 PFH36862.1 - 4.1e-20 71.8 10.4 6.1e-20 71.3 10.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 PFH36862.1 - 7.7e-08 32.6 9.7 3.7e-07 30.4 9.7 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PFH36862.1 - 1e-05 25.3 4.3 2.5e-05 24.1 4.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH36862.1 - 3.5e-05 23.7 9.3 4.2e-05 23.4 5.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PFH36862.1 - 4e-05 23.6 2.4 4e-05 23.6 2.4 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PFH36862.1 - 0.017 15.0 9.3 0.2 11.5 9.3 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PFH36862.1 - 0.023 14.9 4.9 0.15 12.2 4.9 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 PFH36862.1 - 0.027 14.1 12.1 0.081 12.6 11.5 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 PFH36862.1 - 0.063 13.1 15.9 9.4 6.2 15.9 3.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PFH36862.1 - 0.068 12.9 14.0 0.85 9.4 14.0 2.5 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 PFH36862.1 - 0.092 12.9 8.5 0.23 11.6 8.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 PFH36862.1 - 0.22 11.4 10.6 1.5 8.8 10.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Pellino PF04710.14 PFH36862.1 - 0.61 8.7 2.4 0.55 8.9 1.5 1.4 1 1 0 1 1 1 0 Pellino VWA_N2 PF16164.5 PFH36862.1 - 1.4 9.1 6.8 3.8 7.7 4.0 2.1 1 1 1 2 2 2 0 VWA N-terminal RINGv PF12906.7 PFH36862.1 - 2 8.6 8.4 9 6.5 8.3 2.2 1 1 1 2 2 2 0 RING-variant domain PHD PF00628.29 PFH36862.1 - 5 7.1 13.0 91 3.1 10.6 2.6 2 1 0 2 2 1 0 PHD-finger SNARE PF05739.19 PFH36863.1 - 0.00064 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 SNARE domain APG17 PF04108.12 PFH36863.1 - 0.00069 18.8 0.2 0.0011 18.1 0.2 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 NPV_P10 PF05531.12 PFH36863.1 - 0.12 12.9 1.2 3.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.25 PFH36864.1 - 4.2e-71 239.4 0.0 5.4e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36864.1 - 2.4e-34 118.8 0.0 3.6e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 PFH36864.1 - 8e-05 23.3 0.5 0.045 14.5 0.0 3.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 PFH36864.1 - 0.00014 21.3 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PFH36864.1 - 0.014 14.2 0.0 0.029 13.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 PFH36864.1 - 0.075 12.0 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain LRR_4 PF12799.7 PFH36865.1 - 1.6e-38 130.0 26.7 2e-07 31.2 0.2 7.3 5 1 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH36865.1 - 5.2e-31 106.2 21.0 8.6e-14 51.0 0.2 5.9 3 2 3 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 PFH36865.1 - 5.2e-23 81.4 16.3 2.2e-06 27.3 1.9 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 PFH36865.1 - 8.7e-08 31.6 13.4 1.2 9.3 0.1 8.6 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 PFH36865.1 - 6.9e-06 25.9 20.5 0.47 11.2 0.0 9.3 11 0 0 11 11 11 2 Leucine Rich Repeat LRR_5 PF13306.6 PFH36865.1 - 0.091 12.7 0.0 0.5 10.3 0.0 2.1 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Cyclin PF08613.11 PFH36868.1 - 1.7e-33 116.3 0.5 1.7e-33 116.3 0.5 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 PFH36868.1 - 6.8e-10 38.8 0.1 1.2e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Tom37 PF10568.9 PFH36868.1 - 0.019 15.2 0.2 0.052 13.9 0.2 1.6 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Ribophorin_II PF05817.14 PFH36869.1 - 2.7e-13 49.4 0.7 9.8e-13 47.5 0.0 2.2 3 0 0 3 3 3 1 Oligosaccharyltransferase subunit Ribophorin II DUF1768 PF08719.11 PFH36870.1 - 3e-13 50.3 0.0 5.8e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_1 PF00076.22 PFH36870.1 - 8.1e-12 44.8 0.0 4.9e-11 42.3 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.26 PFH36870.1 - 0.00016 22.0 0.0 0.00096 19.5 0.0 2.3 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 PFH36870.1 - 0.036 14.4 0.0 0.19 12.0 0.0 2.2 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain RRM_7 PF16367.5 PFH36870.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif Vpu PF00558.19 PFH36870.1 - 1.9 8.3 7.2 6.4 6.6 7.2 1.9 1 0 0 1 1 1 0 Vpu protein C2 PF00168.30 PFH36871.1 - 0.0013 19.0 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain Glyc_hyd_38C_2 PF18230.1 PFH36873.1 - 8.1e-06 25.9 2.0 20 5.4 0.0 4.4 4 0 0 4 4 4 4 Glycosyl hydrolases family 38 C-terminal sub-domain NHR2 PF08788.11 PFH36873.1 - 1.1 9.0 9.7 87 3.0 0.1 4.3 4 0 0 4 4 4 0 NHR2 domain like OCRE PF17780.1 PFH36874.1 - 1.1 9.4 4.4 1.8 8.6 4.4 1.3 1 0 0 1 1 1 0 OCRE domain NAD_binding_10 PF13460.6 PFH36875.1 - 1.1e-16 61.3 0.0 3.4e-16 59.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 PFH36875.1 - 0.027 14.4 0.1 0.063 13.2 0.1 1.6 1 0 0 1 1 1 0 KR domain ETF_alpha PF00766.19 PFH36878.1 - 2.4e-31 107.6 1.2 6.8e-31 106.2 0.3 2.1 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 PFH36878.1 - 2.5e-22 79.7 5.4 3.9e-22 79.0 5.4 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain GARS_N PF02844.15 PFH36878.1 - 0.1 13.4 0.0 1.3 9.9 0.0 2.5 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain ubiquitin PF00240.23 PFH36879.1 - 0.00044 20.0 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family IGPS PF00218.21 PFH36883.1 - 4.2e-22 78.6 0.0 7.5e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 PFH36883.1 - 0.00061 19.0 0.0 0.0017 17.6 0.0 1.7 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase SAG PF04092.13 PFH36885.1 - 3.4e-14 53.8 3.0 1.9e-08 35.1 0.1 2.4 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36886.1 - 1.7e-18 67.7 16.1 1.7e-11 45.0 6.2 2.1 2 0 0 2 2 2 2 SRS domain Sad1_UNC PF07738.13 PFH36887.1 - 3e-18 66.1 0.1 4.4e-18 65.6 0.1 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal MOZ_SAS PF01853.18 PFH36889.1 - 4.6e-75 251.2 0.0 6.6e-75 250.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 PFH36889.1 - 2.4e-20 71.9 0.5 5.9e-20 70.6 0.5 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 PFH36889.1 - 1.3e-07 31.4 0.4 3.3e-07 30.1 0.4 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 PFH36889.1 - 0.004 17.6 0.0 0.009 16.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_Tnp_IS1595 PF12760.7 PFH36889.1 - 0.15 12.1 3.0 0.34 10.9 3.0 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Alg14 PF08660.11 PFH36890.1 - 1.6e-51 174.7 0.0 3.1e-50 170.5 0.0 2.3 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Ctr PF04145.15 PFH36890.1 - 0.041 14.5 0.2 0.08 13.6 0.0 1.7 2 0 0 2 2 2 0 Ctr copper transporter family Ribonuc_red_sm PF00268.21 PFH36891.1 - 2.4e-113 378.3 2.2 3.8e-113 377.6 2.2 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF445 PF04286.12 PFH36892.1 - 0.0049 16.7 0.3 0.03 14.1 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF445) SAG PF04092.13 PFH36895.1 - 1.2e-05 26.1 5.9 6.7e-05 23.7 1.3 2.5 2 1 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36896.1 - 8.8e-22 78.3 17.9 1.9e-11 44.9 3.9 2.1 2 0 0 2 2 2 2 SRS domain s48_45 PF07422.13 PFH36896.1 - 0.43 11.2 3.6 1.2 9.7 1.3 2.3 2 0 0 2 2 2 0 Sexual stage antigen s48/45 domain SAG PF04092.13 PFH36897.1 - 3.3e-16 60.3 18.3 4.4e-09 37.2 10.7 2.2 1 1 1 2 2 2 2 SRS domain SAG PF04092.13 PFH36898.1 - 2e-08 35.1 1.2 3.5e-08 34.3 1.2 1.3 1 0 0 1 1 1 1 SRS domain Nup84_Nup100 PF04121.13 PFH36899.1 - 4.7e-12 44.9 0.0 1.5e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 Myb_Cef PF11831.8 PFH36900.1 - 1.2e-22 80.7 14.4 2.5e-17 63.3 5.3 4.5 5 1 0 5 5 5 2 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 PFH36900.1 - 7.5e-20 70.9 6.4 6.1e-11 42.3 1.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PFH36900.1 - 1.1e-16 60.9 2.5 2.4e-11 43.7 1.7 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 PFH36900.1 - 0.56 10.4 3.0 1 9.6 0.5 2.6 2 2 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Amino_oxidase PF01593.24 PFH36906.1 - 1.3e-63 215.9 2.5 1.7e-24 87.0 0.0 5.1 4 1 0 4 4 4 4 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PFH36906.1 - 1.3e-08 34.9 0.2 1.3e-08 34.9 0.2 3.4 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain zf-HC5HC2H PF13771.6 PFH36906.1 - 6.1e-08 32.8 3.5 1.2e-07 31.9 3.5 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Pyr_redox_2 PF07992.14 PFH36906.1 - 0.00023 20.5 0.3 0.00052 19.3 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PFH36906.1 - 0.003 16.9 0.4 0.0053 16.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 PFH36906.1 - 0.012 14.7 1.9 0.019 14.1 1.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A zf-HC5HC2H_2 PF13832.6 PFH36906.1 - 0.024 14.8 4.9 0.048 13.8 4.9 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain Thi4 PF01946.17 PFH36906.1 - 0.069 12.4 0.2 0.12 11.5 0.2 1.3 1 0 0 1 1 1 0 Thi4 family IlvN PF07991.12 PFH36906.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox PF00070.27 PFH36906.1 - 0.17 12.5 0.2 0.35 11.4 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PC_rep PF01851.22 PFH36907.1 - 0.059 13.8 1.6 1 9.9 0.1 3.4 3 0 0 3 3 3 0 Proteasome/cyclosome repeat RabGAP-TBC PF00566.18 PFH36908.1 - 2.1e-31 109.3 0.2 4.4e-16 59.2 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Ribosomal_L29 PF00831.23 PFH36909.1 - 4.6e-07 29.7 2.6 9.1e-07 28.8 2.6 1.5 1 0 0 1 1 1 1 Ribosomal L29 protein Penicil_amidase PF01804.18 PFH36910.1 - 1.4e-129 434.1 13.5 3.9e-129 432.6 13.5 1.6 1 1 0 1 1 1 1 Penicillin amidase DUF5407 PF17401.2 PFH36910.1 - 0.14 12.5 0.2 0.28 11.4 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5407) DUF3370 PF11850.8 PFH36911.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3370) zf-C2H2_jaz PF12171.8 PFH36912.1 - 0.0004 20.6 0.1 0.00074 19.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PFH36912.1 - 0.00058 20.2 0.3 0.0012 19.2 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 PFH36912.1 - 0.016 14.9 0.2 0.029 14.1 0.2 1.4 1 0 0 1 1 1 0 U1 zinc finger DUF4746 PF15928.5 PFH36912.1 - 0.83 9.0 7.7 1.5 8.2 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DASH_Spc19 PF08287.11 PFH36912.1 - 6.5 6.6 13.9 13 5.6 13.9 1.5 1 0 0 1 1 1 0 Spc19 Vfa1 PF08432.10 PFH36912.1 - 7.8 6.8 18.1 0.78 10.0 13.2 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 SAG PF04092.13 PFH36913.1 - 5.5e-18 66.0 14.4 2.1e-09 38.3 3.9 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36916.1 - 7.2e-14 52.7 4.5 3.6e-07 31.0 0.8 2.2 2 0 0 2 2 2 2 SRS domain Cu2_monooxygen PF01082.20 PFH36916.1 - 0.17 12.1 1.5 0.2 11.9 0.5 1.6 2 0 0 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain SAG PF04092.13 PFH36917.1 - 1.5e-14 54.9 8.3 4.8e-07 30.6 1.5 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36918.1 - 2.6e-15 57.4 12.1 1.7e-07 32.1 2.3 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36919.1 - 6.4e-17 62.6 11.4 5.3e-08 33.7 5.4 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36920.1 - 1e-16 61.9 5.0 5.3e-11 43.4 0.1 2.4 2 0 0 2 2 2 2 SRS domain zf-GRF PF06839.12 PFH36920.1 - 0.041 14.0 0.1 3.9 7.7 0.1 2.6 2 0 0 2 2 2 0 GRF zinc finger SAG PF04092.13 PFH36921.1 - 1.1e-19 71.5 15.3 2.3e-10 41.4 2.3 2.1 2 0 0 2 2 2 2 SRS domain PulA_N1 PF17999.1 PFH36921.1 - 0.031 15.0 0.0 11 6.8 0.0 2.8 3 0 0 3 3 3 0 Pullulanase N1-terminal domain SAG PF04092.13 PFH36922.1 - 1.1e-18 68.3 10.7 1e-09 39.2 1.0 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36924.1 - 3.2e-16 60.3 4.5 4.4e-08 34.0 0.1 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36925.1 - 5.3e-15 56.4 10.3 4.7e-07 30.6 4.0 2.1 2 0 0 2 2 2 2 SRS domain DND1_DSRM PF14709.7 PFH36925.1 - 0.067 13.5 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 zf-3CxxC_2 PF17180.4 PFH36925.1 - 5.5 7.8 7.1 6.1 7.7 0.2 3.1 3 1 1 4 4 4 0 Zinc-binding domain SAG PF04092.13 PFH36926.1 - 2.9e-19 70.2 8.2 1.1e-10 42.4 2.5 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36927.1 - 2.5e-10 41.2 0.9 1.7e-08 35.3 0.5 2.1 2 0 0 2 2 2 2 SRS domain Pyr_redox_dim PF02852.22 PFH36927.1 - 0.13 12.5 0.0 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SAG PF04092.13 PFH36928.1 - 8.6e-24 84.8 6.7 5.8e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 SRS domain FACT-Spt16_Nlob PF14826.6 PFH36929.1 - 0.14 11.9 0.5 0.7 9.7 0.1 1.9 2 0 0 2 2 2 0 FACT complex subunit SPT16 N-terminal lobe domain SAG PF04092.13 PFH36930.1 - 1.7e-05 25.6 0.4 2.2e-05 25.2 0.4 1.1 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH36932.1 - 1.5e-14 54.9 9.7 4.8e-09 37.1 0.9 2.5 2 1 1 3 3 3 2 SRS domain Phyto-Amp PF15438.6 PFH36932.1 - 0.013 15.4 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma CD52 PF15116.6 PFH36932.1 - 0.79 9.8 4.8 11 6.2 0.0 2.6 2 0 0 2 2 2 0 CAMPATH-1 antigen SAG PF04092.13 PFH36933.1 - 3.7e-15 56.9 8.2 2.2e-07 31.7 0.9 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36934.1 - 8.4e-06 26.6 2.0 0.048 14.4 0.1 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36937.1 - 1.9e-16 61.1 11.2 2.4e-10 41.3 1.2 2.2 2 0 0 2 2 2 2 SRS domain PEP-utilizers PF00391.23 PFH36937.1 - 0.021 14.5 0.4 0.043 13.5 0.4 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain ECSCR PF15820.5 PFH36937.1 - 0.12 12.2 0.1 1.6 8.6 0.1 2.6 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator SAG PF04092.13 PFH36938.1 - 2.1e-15 57.7 14.4 1.9e-07 31.9 2.5 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36939.1 - 3.3e-24 86.1 20.7 4e-08 34.1 2.3 3.2 3 0 0 3 3 3 3 SRS domain Herpes_LMP1 PF05297.11 PFH36939.1 - 8 5.5 9.7 12 5.0 9.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SAG PF04092.13 PFH36941.1 - 5.2e-20 72.6 14.6 9.9e-11 42.5 1.6 2.2 2 0 0 2 2 2 2 SRS domain Cadherin-like PF12733.7 PFH36941.1 - 0.19 12.3 0.4 0.92 10.1 0.1 2.3 3 0 0 3 3 3 0 Cadherin-like beta sandwich domain Herpes_LMP1 PF05297.11 PFH36942.1 - 0.0038 16.5 2.7 0.0061 15.8 2.7 1.2 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) SAG PF04092.13 PFH36943.1 - 2.6e-23 83.2 17.2 2e-11 44.8 0.9 3.2 3 0 0 3 3 3 3 SRS domain SAG PF04092.13 PFH36944.1 - 1.7e-15 57.9 11.4 3.7e-08 34.2 4.3 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36945.1 - 6.6e-16 59.3 17.5 6.7e-08 33.4 4.3 2.1 2 0 0 2 2 2 2 SRS domain DUF4331 PF14224.6 PFH36945.1 - 0.084 12.0 0.1 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4331) Ogr_Delta PF04606.12 PFH36945.1 - 0.53 10.3 3.5 42 4.2 0.1 3.8 4 0 0 4 4 4 0 Ogr/Delta-like zinc finger zf-AD PF07776.15 PFH36946.1 - 0.0055 16.9 3.6 0.063 13.5 0.3 3.0 3 0 0 3 3 3 1 Zinc-finger associated domain (zf-AD) Pcc1 PF09341.10 PFH36946.1 - 0.028 14.6 0.1 5.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Transcription factor Pcc1 zf-AD PF07776.15 PFH36947.1 - 0.0087 16.3 1.2 0.097 12.9 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger associated domain (zf-AD) dCMP_cyt_deam_1 PF00383.23 PFH36949.1 - 5.8e-07 29.3 0.1 1.4e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PFH36949.1 - 2.9e-05 23.9 0.1 5.5e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase WD40 PF00400.32 PFH36950.1 - 2.2e-66 218.2 23.5 3.3e-09 37.2 0.1 9.5 8 2 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH36950.1 - 1.8e-24 85.8 0.2 0.00031 21.0 0.0 6.1 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 PFH36950.1 - 1.2e-08 35.4 0.2 2.2e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 PFH36950.1 - 1.7e-08 33.8 0.0 0.12 11.3 0.0 4.3 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PFH36950.1 - 1.8e-07 30.2 2.8 0.07 11.8 0.1 4.3 4 1 1 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 PFH36950.1 - 0.00014 21.8 0.0 0.055 13.4 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 PFH36950.1 - 0.0014 18.5 0.2 7.3 6.7 0.1 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 PFH36950.1 - 0.0054 15.5 0.1 0.24 10.1 0.1 2.5 1 1 1 2 2 2 1 Nup133 N terminal like Cytochrom_D1 PF02239.16 PFH36950.1 - 0.012 14.2 0.1 3.1 6.3 0.0 2.7 2 1 0 2 2 2 0 Cytochrome D1 heme domain Frtz PF11768.8 PFH36950.1 - 0.014 13.7 0.0 1.4 7.1 0.0 2.9 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 PFH36950.1 - 0.062 13.0 1.0 8.4 6.2 0.0 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature SAG PF04092.13 PFH36952.1 - 3.6e-14 53.7 10.2 1.4e-07 32.4 1.5 2.1 2 0 0 2 2 2 2 SRS domain Hamartin PF04388.12 PFH36953.1 - 0.97 8.0 5.1 1 7.9 5.1 1.1 1 0 0 1 1 1 0 Hamartin protein SAG PF04092.13 PFH36954.1 - 9.7e-11 42.6 6.1 1.7e-10 41.8 6.1 1.4 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH36955.1 - 9.8e-12 45.8 4.4 1.3e-11 45.4 4.4 1.1 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH36956.1 - 2.3e-09 38.1 2.7 3.4e-09 37.6 2.7 1.3 1 0 0 1 1 1 1 SRS domain NKWYS PF10364.9 PFH36956.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein SAG PF04092.13 PFH36957.1 - 2.1e-17 64.1 3.7 4.2e-08 34.0 0.9 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36958.1 - 1.6e-18 67.7 16.6 7.1e-11 43.0 5.6 2.2 2 0 0 2 2 2 2 SRS domain PulA_N1 PF17999.1 PFH36958.1 - 0.064 14.0 0.3 23 5.8 0.0 2.7 3 0 0 3 3 3 0 Pullulanase N1-terminal domain SAG PF04092.13 PFH36959.1 - 2.5e-19 70.3 14.8 6e-11 43.2 5.5 2.3 2 0 0 2 2 2 2 SRS domain PulA_N1 PF17999.1 PFH36959.1 - 0.11 13.3 0.1 23 5.8 0.0 2.7 3 0 0 3 3 3 0 Pullulanase N1-terminal domain SAG PF04092.13 PFH36960.1 - 8.4e-21 75.1 20.8 6.2e-11 43.2 9.2 2.3 2 1 0 2 2 2 2 SRS domain PulA_N1 PF17999.1 PFH36960.1 - 0.13 13.0 0.8 2.3 9.0 0.2 2.6 3 0 0 3 3 3 0 Pullulanase N1-terminal domain AFT PF08731.11 PFH36960.1 - 1.7 9.1 3.8 5.4 7.5 0.1 2.7 2 1 0 2 2 2 0 Transcription factor AFT SAG PF04092.13 PFH36961.1 - 6e-19 69.1 18.2 6e-11 43.3 6.5 2.4 2 1 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36962.1 - 2.9e-18 66.9 11.2 2.4e-10 41.3 3.0 2.3 2 0 0 2 2 2 2 SRS domain PulA_N1 PF17999.1 PFH36962.1 - 0.086 13.6 0.0 7.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Pullulanase N1-terminal domain SAG PF04092.13 PFH36963.1 - 4.2e-19 69.6 16.1 5.9e-11 43.3 5.3 2.1 2 0 0 2 2 2 2 SRS domain PulA_N1 PF17999.1 PFH36963.1 - 0.14 12.9 0.1 6.2 7.6 0.1 2.6 2 0 0 2 2 2 0 Pullulanase N1-terminal domain YEATS PF03366.16 PFH36964.1 - 3.5e-25 87.8 0.0 5.2e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 YEATS family AAA_16 PF13191.6 PFH36965.1 - 0.0033 17.8 4.8 0.0067 16.8 0.6 2.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PFH36965.1 - 0.016 15.5 0.1 0.39 11.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain Torsin PF06309.11 PFH36965.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Torsin PI3_PI4_kinase PF00454.27 PFH36966.1 - 2e-38 132.7 0.0 4.8e-36 124.8 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 PFH36966.1 - 6.2e-16 58.3 0.0 2.7e-12 46.5 0.0 2.2 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 PFH36966.1 - 0.0028 17.6 0.0 0.0092 15.9 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 SAG PF04092.13 PFH36968.1 - 3.9e-14 53.6 1.4 4.7e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH36969.1 - 2.2e-12 47.9 5.4 8.9e-10 39.5 0.1 2.5 3 0 0 3 3 3 2 SRS domain SAG PF04092.13 PFH36970.1 - 6e-16 59.4 6.7 6.3e-08 33.5 1.5 2.2 2 0 0 2 2 2 2 SRS domain Mt_ATP-synt_D PF05873.12 PFH36970.1 - 0.23 11.3 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) SAG PF04092.13 PFH36971.1 - 1.9e-10 41.6 3.3 2.9e-10 41.0 3.3 1.2 1 0 0 1 1 1 1 SRS domain SAG PF04092.13 PFH36972.1 - 0.00092 20.0 0.2 0.0018 19.1 0.2 1.4 1 1 0 1 1 1 1 SRS domain SAG PF04092.13 PFH36973.1 - 4.5e-21 76.0 6.1 2.8e-10 41.1 0.7 2.2 2 0 0 2 2 2 2 SRS domain s48_45 PF07422.13 PFH36973.1 - 0.058 14.0 0.6 0.57 10.8 0.1 2.4 3 0 0 3 3 3 0 Sexual stage antigen s48/45 domain DUF2286 PF10051.9 PFH36973.1 - 0.18 11.5 0.1 0.29 10.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) SAG PF04092.13 PFH36974.1 - 6.7e-14 52.8 11.4 1.1e-09 39.1 2.3 2.2 2 0 0 2 2 2 2 SRS domain Pkinase PF00069.25 PFH36975.1 - 2.2e-55 187.9 0.0 3.1e-37 128.4 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH36975.1 - 2.1e-23 83.0 0.4 1.1e-16 60.9 0.3 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PFH36975.1 - 8.6e-05 22.0 2.4 0.0029 17.0 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 PFH36975.1 - 0.00015 21.1 0.6 0.00032 20.1 0.6 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH36975.1 - 0.0018 18.3 0.3 0.32 10.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PFH36975.1 - 0.074 12.0 0.2 0.12 11.3 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 PFH36975.1 - 0.18 10.8 0.1 0.3 10.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PP2C PF00481.21 PFH36977.1 - 2.7e-32 112.4 0.1 6.6e-20 71.8 0.1 4.2 4 0 0 4 4 4 4 Protein phosphatase 2C TetR_C_16 PF17920.1 PFH36977.1 - 4.4 7.6 8.2 6.5 7.0 0.9 3.8 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain zf-C3HC4_2 PF13923.6 PFH36978.1 - 6.6e-09 35.5 10.3 1.3e-08 34.5 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PFH36978.1 - 7.2e-08 32.2 5.2 1.5e-07 31.2 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PFH36978.1 - 2.6e-07 30.4 8.5 5.3e-07 29.4 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH36978.1 - 1.4e-06 28.2 10.5 1.4e-06 28.2 10.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 PFH36978.1 - 1.7e-06 28.3 10.0 3.8e-06 27.1 10.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PFH36978.1 - 1.9e-06 27.8 6.3 3.8e-06 26.8 6.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PFH36978.1 - 0.00011 22.0 7.9 0.00045 20.0 8.1 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 PFH36978.1 - 0.00019 21.6 0.0 0.00045 20.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-C3HC4_4 PF15227.6 PFH36978.1 - 0.0043 17.2 11.2 0.01 15.9 11.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PFH36978.1 - 0.0059 16.4 3.3 0.015 15.1 3.3 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Peptidase_C97 PF05903.14 PFH36978.1 - 0.036 13.9 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain zf-rbx1 PF12678.7 PFH36978.1 - 0.061 13.6 5.3 0.2 12.0 5.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 PFH36978.1 - 0.18 11.6 6.8 0.38 10.6 6.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3774 PF12609.8 PFH36978.1 - 0.42 11.7 5.9 4.3 8.4 0.1 5.5 4 0 0 4 4 3 0 Wound-induced protein zf-P11 PF03854.14 PFH36978.1 - 1.2 8.9 5.2 3.5 7.4 5.2 1.8 1 0 0 1 1 1 0 P-11 zinc finger Serglycin PF04360.12 PFH36978.1 - 5.9 6.8 5.6 1.3 9.0 0.5 2.3 2 0 0 2 2 2 0 Serglycin F-box PF00646.33 PFH36979.1 - 0.17 11.8 0.1 0.45 10.5 0.1 1.7 1 0 0 1 1 1 0 F-box domain FAD_binding_2 PF00890.24 PFH36982.1 - 7.7e-119 397.5 6.2 7.7e-119 397.5 6.2 1.7 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 PFH36982.1 - 3e-42 143.6 1.6 5e-42 142.9 1.6 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 PFH36982.1 - 0.00023 20.5 0.4 0.088 12.0 0.1 2.5 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 PFH36982.1 - 0.00035 19.9 0.3 0.00071 18.9 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PFH36982.1 - 0.00092 18.5 2.4 0.002 17.5 0.1 2.6 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PFH36982.1 - 0.0027 16.9 5.7 0.034 13.2 4.6 2.7 2 1 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 PFH36982.1 - 0.051 13.2 3.5 0.037 13.6 1.0 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PFH36982.1 - 0.13 11.2 0.5 0.91 8.5 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein AP2 PF00847.20 PFH36983.1 - 1.5e-24 85.9 5.4 3e-13 49.8 0.3 2.6 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.6 PFH36983.1 - 2.7e-16 59.7 0.0 4.5e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal DUF1627 PF07789.12 PFH36983.1 - 0.063 12.9 0.5 0.25 11.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1627) PRMT5 PF05185.16 PFH36984.1 - 2.3e-50 170.8 0.0 3.7e-35 121.3 0.0 2.2 2 0 0 2 2 2 2 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 PFH36984.1 - 1.2e-38 132.7 0.0 2.2e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 PFH36984.1 - 2e-18 66.5 0.0 4.5e-06 26.0 0.0 4.1 4 0 0 4 4 4 4 PRMT5 TIM barrel domain Exo5 PF09810.9 PFH36985.1 - 5e-56 190.8 0.0 2.1e-55 188.7 0.0 1.9 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Methyltransf_5 PF01795.19 PFH36988.1 - 2.5e-60 204.6 0.0 7e-33 114.4 0.0 3.4 4 0 0 4 4 4 3 MraW methylase family Methyltransf_31 PF13847.6 PFH36988.1 - 4.1e-05 23.4 0.0 0.03 14.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 PFH36988.1 - 0.0051 17.5 0.2 0.21 12.3 0.1 2.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PFH36988.1 - 0.0053 16.3 0.2 1.9 8.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_12 PF08242.12 PFH36988.1 - 0.02 15.6 0.0 13 6.6 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.12 PFH36988.1 - 0.036 14.7 0.4 12 6.7 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 PFH36988.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 PFH36988.1 - 0.17 11.6 0.1 0.41 10.4 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 PFH36988.1 - 0.17 11.2 0.1 19 4.5 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.17 PFH36988.1 - 0.22 10.7 0.0 4 6.6 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase P_C10 PF14974.6 PFH36990.1 - 0.00017 21.7 0.0 0.0015 18.6 0.0 2.5 3 0 0 3 3 3 1 Protein C10 TPR_1 PF00515.28 PFH36990.1 - 0.00081 19.1 1.3 0.32 10.9 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 PFH36990.1 - 0.035 14.2 2.8 0.72 10.1 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 PFH36990.1 - 0.079 13.6 0.2 0.079 13.6 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 PFH36990.1 - 1.3 9.6 8.1 0.22 12.1 0.9 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 PFH36991.1 - 3.3e-10 39.4 31.7 6.5e-10 38.5 30.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily A_deaminase PF00962.22 PFH36992.1 - 9.1e-49 166.5 0.0 1e-41 143.4 0.0 3.1 3 0 0 3 3 3 3 Adenosine/AMP deaminase FerA PF08165.11 PFH36992.1 - 0.054 13.4 0.3 0.13 12.3 0.3 1.5 1 0 0 1 1 1 0 FerA (NUC095) domain Ribosomal_L1 PF00687.21 PFH36993.1 - 6.6e-43 146.8 2.3 7.3e-43 146.7 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 PFH36993.1 - 0.009 16.1 1.8 0.023 14.8 1.8 1.7 1 1 0 1 1 1 1 Protein of unknown function TetR PF13972.6 PFH36993.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial transcriptional repressor Ribosomal_S24e PF01282.19 PFH36994.1 - 1.1e-29 102.2 0.0 2e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e MIP PF00230.20 PFH36995.1 - 6.2e-23 81.7 13.1 9.9e-23 81.0 13.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein EpuA PF11772.8 PFH36995.1 - 3.7 7.3 7.1 0.24 11.1 1.1 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta DTC PF18102.1 PFH36996.1 - 7.6e-48 162.0 0.0 1.2e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Deltex C-terminal domain WWE PF02825.20 PFH36996.1 - 6.3e-22 77.9 0.2 7.6e-14 52.1 0.3 2.5 2 0 0 2 2 2 2 WWE domain zf-RING_2 PF13639.6 PFH36996.1 - 6.1e-05 23.3 1.4 0.00044 20.5 0.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 PFH36996.1 - 0.00093 19.4 0.6 0.0025 18.1 0.1 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PFH36996.1 - 0.00098 19.0 0.3 0.0043 16.9 0.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 PFH36996.1 - 0.0056 16.5 0.1 0.018 14.9 0.1 1.9 1 0 0 1 1 1 1 PHD-finger zf-RING_UBOX PF13445.6 PFH36996.1 - 0.014 15.4 0.2 0.047 13.7 0.2 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PFH36996.1 - 0.042 13.7 0.4 0.042 13.7 0.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PFH36996.1 - 0.054 13.3 2.6 0.082 12.7 0.2 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_5 PF14634.6 PFH36996.1 - 0.096 12.7 1.9 0.094 12.7 0.3 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 PFH36996.1 - 0.14 12.3 1.3 0.38 10.8 0.6 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PLAC PF08686.11 PFH36996.1 - 0.52 11.1 3.7 6.4 7.6 0.3 2.6 2 0 0 2 2 2 0 PLAC (protease and lacunin) domain V-ATPase_H_N PF03224.14 PFH36997.1 - 0.0026 17.1 0.1 0.0031 16.8 0.1 1.1 1 0 0 1 1 1 1 V-ATPase subunit H DUF4168 PF13767.6 PFH36997.1 - 0.013 16.7 1.3 0.11 13.7 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) FliL PF03748.14 PFH36997.1 - 0.19 12.3 1.8 0.48 11.0 0.3 2.2 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL Synaptobrevin PF00957.21 PFH36998.1 - 4.2e-17 61.7 1.4 7e-17 61.0 1.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PFH36998.1 - 1.2e-05 25.2 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2935 PF11155.8 PFH36998.1 - 0.18 12.1 0.6 0.73 10.2 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) DPCD PF14913.6 PFH36999.1 - 1.3e-62 210.6 0.0 1.5e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 DPCD protein family RRM_1 PF00076.22 PFH37000.1 - 4.5e-16 58.4 0.1 1.1e-15 57.2 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-Tim10_DDP PF02953.15 PFH37001.1 - 1.6e-19 69.3 0.1 1.8e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger MFS_1 PF07690.16 PFH37002.1 - 1.6e-10 40.5 31.8 2.2e-10 40.0 31.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily COX2_TM PF02790.15 PFH37002.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.7 2 1 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain DUF2178 PF09946.9 PFH37002.1 - 8 6.7 11.9 5.6 7.2 3.6 3.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2178) Cep57_MT_bd PF06657.13 PFH37004.1 - 0.12 12.8 1.8 0.3 11.6 1.8 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Vpu PF00558.19 PFH37004.1 - 5.5 6.8 8.0 5.2 6.9 4.8 2.3 1 1 1 2 2 2 0 Vpu protein Mito_fiss_reg PF05308.11 PFH37005.1 - 0.0011 19.1 1.5 0.0011 19.1 1.5 1.6 2 0 0 2 2 2 1 Mitochondrial fission regulator Atg14 PF10186.9 PFH37005.1 - 0.12 11.4 1.8 0.22 10.6 1.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 PFH37005.1 - 0.82 10.2 6.0 0.43 11.1 3.1 2.0 2 1 0 2 2 2 0 Protein of unknown function DUF16 Pyr_excise PF03013.14 PFH37007.1 - 0.096 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Cut8 PF08559.10 PFH37012.1 - 0.22 11.1 2.2 0.49 10.0 2.2 1.7 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein Sacchrp_dh_NADP PF03435.18 PFH37013.1 - 2.1e-11 44.2 0.1 3e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 PFH37013.1 - 0.15 12.0 0.1 0.76 9.6 0.1 1.9 1 1 0 1 1 1 0 NAD(P)H-binding Fer2_3 PF13085.6 PFH37014.1 - 1.3e-31 108.9 0.3 5.8e-31 106.7 0.3 2.1 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 PFH37014.1 - 8.9e-10 39.0 4.6 8.9e-10 39.0 4.6 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 PFH37014.1 - 1.6e-07 31.7 5.5 1.6e-07 31.7 5.5 2.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 PFH37014.1 - 3.4e-06 27.1 3.8 3.4e-06 27.1 3.8 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 PFH37014.1 - 0.0013 18.6 3.5 0.0022 17.9 0.7 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_22 PF17179.4 PFH37014.1 - 0.44 11.4 8.1 2.3 9.1 0.3 3.2 3 0 0 3 3 3 0 4Fe-4S dicluster domain CPSase_L_D2 PF02786.17 PFH37015.1 - 2.7e-107 357.1 0.3 5.3e-80 267.9 0.1 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 PFH37015.1 - 1.1e-47 161.0 0.0 2.5e-47 159.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 PFH37015.1 - 8.7e-46 156.1 0.0 2.6e-45 154.5 0.0 1.9 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 PFH37015.1 - 3.2e-37 127.6 0.0 1.5e-36 125.4 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 PFH37015.1 - 1.4e-16 60.5 0.7 1.6e-08 34.4 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 PFH37015.1 - 1.9e-14 53.5 0.0 7.8e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 PFH37015.1 - 3.7e-12 46.3 0.0 8.4e-10 38.7 0.0 3.2 2 1 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 PFH37015.1 - 2e-11 43.8 2.8 8e-05 22.3 0.1 3.0 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus DJ-1_PfpI PF01965.24 PFH37015.1 - 5.1e-07 29.6 0.0 0.00058 19.7 0.0 3.4 3 0 0 3 3 3 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 PFH37015.1 - 2e-05 24.4 0.1 0.00016 21.5 0.1 2.1 1 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 PFH37015.1 - 9.9e-05 22.4 0.4 0.066 13.3 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 PFH37015.1 - 0.00046 20.0 0.8 0.0072 16.1 0.0 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 PFH37015.1 - 0.0096 15.4 0.0 0.05 13.0 0.1 2.0 2 0 0 2 2 2 1 ATP-grasp domain TrkA_N PF02254.18 PFH37015.1 - 0.07 13.4 0.0 20 5.5 0.0 3.4 3 0 0 3 3 3 0 TrkA-N domain TPK_catalytic PF04263.16 PFH37016.1 - 9e-25 87.1 0.0 5.3e-24 84.6 0.0 2.0 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 PFH37016.1 - 4.1e-12 45.6 0.1 1.6e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain RRM_1 PF00076.22 PFH37017.1 - 5.4e-17 61.4 0.2 1.7e-09 37.3 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GYF_2 PF14237.6 PFH37017.1 - 3.6e-08 33.1 0.1 1.1e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 GYF domain 2 RRM_7 PF16367.5 PFH37017.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Smg4_UPF3 PF03467.15 PFH37017.1 - 0.89 9.6 0.0 0.89 9.6 0.0 3.2 4 1 0 4 4 4 0 Smg-4/UPF3 family Kei1 PF08552.11 PFH37017.1 - 3.8 7.4 4.7 0.8 9.5 0.3 2.2 2 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 F-box-like PF12937.7 PFH37019.1 - 0.0077 16.1 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PFH37019.1 - 0.079 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 F-box domain Clathrin PF00637.20 PFH37020.1 - 0.00017 21.4 4.7 0.58 10.0 0.1 4.4 3 1 2 5 5 5 2 Region in Clathrin and VPS Nic96 PF04097.14 PFH37020.1 - 0.014 13.9 2.3 3.3 6.1 0.0 3.0 2 1 1 3 3 3 0 Nup93/Nic96 ANAPC3 PF12895.7 PFH37020.1 - 0.2 11.9 2.1 4.1 7.7 0.2 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 PFH37020.1 - 0.88 9.5 6.4 3.6 7.6 0.4 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 PFH37020.1 - 2.1 8.7 18.7 0.44 10.8 0.4 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Metallophos PF00149.28 PFH37021.1 - 1.1e-30 107.6 0.0 1.8e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5428 PF17493.2 PFH37021.1 - 0.31 11.5 2.1 0.74 10.3 2.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5428) AP2 PF00847.20 PFH37023.1 - 2.5e-11 43.7 2.9 2.5e-11 43.7 2.9 2.0 2 0 0 2 2 2 1 AP2 domain Clat_adaptor_s PF01217.20 PFH37025.1 - 3.4e-46 156.7 0.4 3.9e-46 156.5 0.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ATP_bind_3 PF01171.20 PFH37026.1 - 4.3e-24 85.3 0.0 4.2e-18 65.8 0.0 3.3 3 0 0 3 3 3 3 PP-loop family ATP_bind_1 PF03029.17 PFH37027.1 - 1.9e-76 257.0 0.0 2.7e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 PFH37027.1 - 0.00036 20.8 0.0 0.019 15.3 0.0 2.8 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 PFH37027.1 - 0.0012 18.9 0.0 0.025 14.6 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase CLP1_P PF16575.5 PFH37027.1 - 0.0038 17.1 0.0 0.16 11.8 0.0 2.4 2 1 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 PFH37027.1 - 0.0054 17.3 0.0 0.011 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 PFH37027.1 - 0.0088 16.5 0.3 0.049 14.1 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 PFH37027.1 - 0.013 15.9 0.0 0.058 13.8 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 PFH37027.1 - 0.021 14.2 0.0 0.07 12.5 0.0 1.9 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 PFH37027.1 - 0.022 14.5 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 PFH37027.1 - 0.036 14.5 0.0 0.088 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 PFH37027.1 - 0.039 14.1 0.0 0.066 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PFH37027.1 - 0.097 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 PFH37027.1 - 0.1 12.0 0.0 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Fer4_NifH PF00142.18 PFH37027.1 - 0.14 11.6 0.0 13 5.1 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ADK PF00406.22 PFH37027.1 - 0.16 12.0 0.4 0.62 10.2 0.1 2.2 2 1 1 3 3 3 0 Adenylate kinase Fer2 PF00111.27 PFH37030.1 - 3.5e-18 65.3 1.2 7.1e-18 64.3 1.2 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 PFH37030.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Arf PF00025.21 PFH37031.1 - 2e-63 213.0 0.0 2.2e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PFH37031.1 - 6.9e-11 41.9 0.0 9e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PFH37031.1 - 4.5e-10 39.2 0.3 6e-07 28.9 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 PFH37031.1 - 2.3e-09 37.5 0.0 5.6e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PFH37031.1 - 1.8e-08 34.2 0.0 2.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 PFH37031.1 - 1e-07 32.0 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PFH37031.1 - 2.2e-06 27.2 0.0 2.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PFH37031.1 - 0.00074 19.1 0.1 0.015 14.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain CENP-M PF11111.8 PFH37031.1 - 0.0099 15.1 0.0 0.035 13.3 0.0 1.7 2 0 0 2 2 2 1 Centromere protein M (CENP-M) cobW PF02492.19 PFH37031.1 - 0.012 15.2 0.0 0.48 10.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 PFH37031.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 PFH37031.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain SAG PF04092.13 PFH37032.1 - 2.1e-52 177.4 12.4 2.8e-26 92.8 3.8 2.1 2 0 0 2 2 2 2 SRS domain COBRA PF04833.15 PFH37032.1 - 0.046 13.6 0.3 0.046 13.6 0.3 1.9 2 1 0 2 2 2 0 COBRA-like protein SAG PF04092.13 PFH37033.1 - 9.6e-47 159.1 21.8 1.6e-25 90.4 1.2 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37034.1 - 1e-50 171.9 10.7 9.3e-26 91.2 0.5 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37035.1 - 2.1e-39 135.3 3.1 3.4e-21 76.4 0.0 2.1 2 0 0 2 2 2 2 SRS domain MRP_L53 PF10780.9 PFH37035.1 - 0.045 13.9 0.5 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 SAG PF04092.13 PFH37036.1 - 3.4e-45 154.1 12.8 1.6e-23 83.9 0.3 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37037.1 - 3.7e-48 163.6 17.3 7.2e-26 91.5 3.1 2.2 2 0 0 2 2 2 2 SRS domain Ig_5 PF16681.5 PFH37037.1 - 0.048 14.1 0.4 0.21 12.0 0.3 2.2 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain YfhO PF09586.10 PFH37037.1 - 0.096 10.9 0.1 0.12 10.6 0.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SAG PF04092.13 PFH37038.1 - 1.8e-45 155.0 5.7 1e-25 91.0 0.1 2.1 2 0 0 2 2 2 2 SRS domain MRP_L53 PF10780.9 PFH37038.1 - 0.034 14.3 1.6 5.4 7.3 0.1 2.6 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 SAG PF04092.13 PFH37039.1 - 7.3e-48 162.7 15.0 5.9e-26 91.8 1.1 2.1 2 0 0 2 2 2 2 SRS domain Fer4_20 PF14691.6 PFH37039.1 - 0.023 14.4 3.3 0.23 11.3 0.1 2.6 2 1 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster YfhO PF09586.10 PFH37039.1 - 0.11 10.8 0.1 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SAG PF04092.13 PFH37040.1 - 9.7e-48 162.3 12.8 1e-25 91.0 0.1 2.3 2 0 0 2 2 2 2 SRS domain MRP_L53 PF10780.9 PFH37040.1 - 0.03 14.5 0.6 5 7.4 0.1 3.0 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 SAG PF04092.13 PFH37041.1 - 4.7e-47 160.1 11.4 1.8e-26 93.4 0.7 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37042.1 - 2.5e-45 154.5 12.8 1.2e-25 90.7 1.4 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37043.1 - 5.4e-49 166.4 17.6 1e-27 97.5 0.8 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37044.1 - 7.2e-47 159.5 12.2 9.5e-27 94.4 1.9 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37045.1 - 9.1e-47 159.1 11.7 1.1e-25 90.9 0.5 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37046.1 - 3.6e-81 270.4 41.0 4.9e-24 85.6 1.4 4.2 4 0 0 4 4 4 4 SRS domain SAG PF04092.13 PFH37047.1 - 3.1e-47 160.7 9.8 1.9e-25 90.2 2.9 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37048.1 - 1.8e-46 158.1 22.1 1.2e-25 90.9 4.2 2.1 2 0 0 2 2 2 2 SRS domain DUF1263 PF06882.12 PFH37048.1 - 0.044 13.8 0.1 0.9 9.6 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) SAG PF04092.13 PFH37049.1 - 8.1e-40 136.7 9.9 5.6e-20 72.5 3.4 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37051.1 - 5.3e-46 156.7 11.5 2e-25 90.1 0.6 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37052.1 - 1.2e-46 158.7 14.8 2.5e-25 89.8 0.9 2.0 2 0 0 2 2 2 2 SRS domain TIP120 PF08623.10 PFH37053.1 - 1.3e-20 73.8 0.0 1e-19 70.9 0.0 2.6 1 1 0 1 1 1 1 TATA-binding protein interacting (TIP20) MMS19_N PF14500.6 PFH37053.1 - 0.00016 21.4 4.7 0.078 12.5 0.1 4.0 4 0 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II Vac14_Fab1_bd PF12755.7 PFH37053.1 - 0.00032 21.2 0.7 0.049 14.2 0.0 3.7 2 1 0 2 2 2 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 PFH37053.1 - 0.00053 19.9 16.9 0.12 12.4 0.0 6.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat U3snoRNP10 PF12397.8 PFH37053.1 - 0.068 13.5 11.6 1.2 9.5 0.6 5.4 5 1 0 5 5 5 0 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 PFH37053.1 - 0.19 12.1 46.4 0.2 12.1 0.2 9.1 7 2 2 9 9 9 0 HEAT repeats HEAT_EZ PF13513.6 PFH37053.1 - 0.23 12.0 0.1 0.23 12.0 0.1 12.0 11 1 1 12 12 12 0 HEAT-like repeat TilS PF09179.11 PFH37053.1 - 1.8 9.1 7.9 12 6.5 0.1 4.6 5 0 0 5 5 5 0 TilS substrate binding domain OB_NTP_bind PF07717.16 PFH37055.1 - 3.2e-10 40.2 0.0 6.4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PFH37055.1 - 2.4e-06 27.8 0.0 2.4e-06 27.8 0.0 3.9 4 1 0 4 4 4 1 Helicase associated domain (HA2) PI3K_1B_p101 PF10486.9 PFH37055.1 - 9.8 3.8 13.3 19 2.9 13.3 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PrsW-protease PF13367.6 PFH37057.1 - 1.5e-05 24.5 12.9 0.00014 21.3 7.6 3.8 2 1 0 2 2 2 2 PrsW family intramembrane metalloprotease PAP_assoc PF03828.19 PFH37058.1 - 0.0043 17.2 0.0 0.0097 16.1 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Enkurin PF13864.6 PFH37059.1 - 0.0082 16.6 1.3 0.046 14.2 2.0 1.7 2 0 0 2 2 2 1 Calmodulin-binding CALM_bind PF16025.5 PFH37059.1 - 0.17 12.4 2.8 0.38 11.2 2.8 1.5 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding MCM PF00493.23 PFH37061.1 - 2.1e-90 301.7 0.0 1.5e-79 266.2 0.0 2.3 2 0 0 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 PFH37061.1 - 1.5e-35 121.8 0.7 2.6e-35 121.0 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PFH37061.1 - 2.4e-19 69.5 0.0 6e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 PFH37061.1 - 3.3e-11 43.7 0.1 9.8e-11 42.2 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 PFH37061.1 - 2.3e-08 33.7 0.0 1.2e-05 24.7 0.0 2.7 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 PFH37061.1 - 1.3e-06 28.2 1.4 0.0012 18.6 0.0 3.5 2 1 1 3 3 3 2 Sigma-54 interaction domain AAA_5 PF07728.14 PFH37061.1 - 0.00018 21.5 0.0 0.00068 19.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 PFH37061.1 - 0.00068 19.5 0.0 0.0083 16.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 PFH37061.1 - 0.018 15.5 0.0 0.055 13.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AP2 PF00847.20 PFH37062.1 - 0.1 12.8 1.0 22 5.4 0.0 3.5 3 0 0 3 3 3 0 AP2 domain DUF4333 PF14230.6 PFH37064.1 - 0.049 13.9 0.6 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4333) GWT1 PF06423.12 PFH37066.1 - 3.7e-24 85.6 0.5 3.7e-24 85.6 0.5 1.9 2 0 0 2 2 2 1 GWT1 Ycf4 PF02392.16 PFH37066.1 - 0.0048 16.5 0.7 0.01 15.4 0.7 1.4 1 0 0 1 1 1 1 Ycf4 Ribosomal_L9_N PF01281.19 PFH37069.1 - 5.7e-15 54.6 0.0 1.1e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DXPR_C PF13288.6 PFH37070.1 - 4.2e-39 133.4 0.0 6.6e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_reductoisom PF02670.16 PFH37070.1 - 1.2e-38 132.8 0.1 1.8e-38 132.2 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.12 PFH37070.1 - 2.8e-36 123.5 0.0 2.7e-35 120.4 0.0 2.3 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain NAD_binding_3 PF03447.16 PFH37070.1 - 0.14 12.8 0.4 1.4 9.6 0.2 2.7 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain AP2 PF00847.20 PFH37071.1 - 4.8e-26 90.7 30.1 1.3e-09 38.1 0.2 3.9 4 0 0 4 4 4 3 AP2 domain AbiEi_3 PF11459.8 PFH37071.1 - 0.33 10.6 1.5 0.63 9.7 1.5 1.3 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Xpo1 PF08389.12 PFH37072.1 - 1.1e-08 35.3 0.0 3.3e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 Exportin 1-like protein G-patch PF01585.23 PFH37073.1 - 3.6e-15 55.6 1.0 8.6e-15 54.4 1.0 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 PFH37073.1 - 5.4e-05 22.9 0.1 0.0001 22.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 PFH37073.1 - 0.0014 18.7 2.3 0.0036 17.4 0.3 2.4 2 0 0 2 2 2 1 G-patch domain SR-25 PF10500.9 PFH37073.1 - 3 7.4 10.3 3.5 7.2 6.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PRA1 PF03208.19 PFH37074.1 - 1.7e-19 69.8 5.1 2.4e-19 69.4 5.1 1.1 1 0 0 1 1 1 1 PRA1 family protein MCLC PF05934.11 PFH37075.1 - 2.5 6.7 5.1 6.3 5.4 5.1 1.6 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) MAM33 PF02330.16 PFH37076.1 - 1.1e-33 116.9 2.8 8.9e-33 114.0 2.8 1.9 1 1 0 1 1 1 1 Mitochondrial glycoprotein FERM_C PF09380.10 PFH37076.1 - 0.016 15.6 0.2 0.14 12.6 0.0 2.2 2 0 0 2 2 2 0 FERM C-terminal PH-like domain Toxin_R_bind_N PF07953.12 PFH37076.1 - 0.053 13.2 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding DUF2812 PF11193.8 PFH37076.1 - 0.18 12.0 1.4 0.32 11.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2812) NUDIX PF00293.28 PFH37077.1 - 1.9e-17 63.5 0.3 2.4e-17 63.2 0.3 1.0 1 0 0 1 1 1 1 NUDIX domain Ras PF00071.22 PFH37078.1 - 1.2e-66 223.3 0.5 1.4e-66 223.1 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH37078.1 - 3e-36 124.3 0.1 5.2e-36 123.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH37078.1 - 2e-16 59.9 0.1 2.5e-16 59.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PFH37078.1 - 1.4e-05 25.1 0.2 0.13 12.1 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 PFH37078.1 - 3.4e-05 23.3 0.1 3.9e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PFH37078.1 - 7.6e-05 22.2 0.0 9.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 PFH37078.1 - 0.00012 21.7 0.4 0.00022 20.8 0.2 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PFH37078.1 - 0.00014 21.9 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 PFH37078.1 - 0.016 14.9 0.1 0.079 12.7 0.1 2.0 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 PFH37078.1 - 0.048 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 PFH37078.1 - 0.049 14.0 0.0 0.095 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 PFH37078.1 - 0.056 13.4 0.0 0.1 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 PFH37078.1 - 0.066 12.7 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 PFH37078.1 - 0.081 13.2 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 PFH37078.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein 2-Hacid_dh_C PF02826.19 PFH37079.1 - 6.5e-49 165.7 0.0 8.8e-49 165.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PFH37079.1 - 9.3e-06 25.3 0.0 0.00057 19.6 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PFH37079.1 - 2.1e-05 24.7 0.0 4.8e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 PFH37079.1 - 0.0038 17.8 0.0 0.021 15.4 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent LysR_substrate PF03466.20 PFH37079.1 - 0.0053 16.1 0.0 0.0098 15.3 0.0 1.5 1 1 0 1 1 1 1 LysR substrate binding domain Shikimate_DH PF01488.20 PFH37079.1 - 0.0095 16.0 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 PFH37079.1 - 0.078 13.4 0.0 6.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding 2OG-FeII_Oxy_3 PF13640.6 PFH37084.1 - 4.2e-15 56.4 0.0 7.9e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 PFH37084.1 - 2e-07 31.6 0.0 3.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TRAPPC-Trs85 PF12739.7 PFH37085.1 - 1.2e-91 307.8 0.0 2.2e-91 306.8 0.0 1.4 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.6 PFH37085.1 - 0.011 15.2 0.7 0.1 12.0 0.0 2.1 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP MFAP1 PF06991.11 PFH37087.1 - 5.1e-68 229.2 30.1 5.1e-68 229.2 30.1 2.1 2 0 0 2 2 2 1 Microfibril-associated/Pre-mRNA processing TPR_2 PF07719.17 PFH37088.1 - 1.1e-12 47.0 0.5 0.0008 19.3 0.7 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 PFH37088.1 - 1.4e-10 40.5 0.2 0.00019 21.1 0.5 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 PFH37088.1 - 1.3e-07 31.8 1.3 7e-06 26.2 0.9 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 PFH37088.1 - 1.2e-05 25.1 0.2 0.066 13.5 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 PFH37088.1 - 1.4e-05 25.7 1.7 0.0019 18.8 0.0 3.1 2 1 1 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH37088.1 - 0.00023 21.3 0.3 0.00087 19.5 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 PFH37088.1 - 0.00052 19.6 0.9 0.16 11.7 1.2 3.0 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.6 PFH37088.1 - 0.044 14.6 2.3 14 6.8 0.0 4.1 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 PFH37088.1 - 0.083 13.1 0.0 0.31 11.2 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 PFH37088.1 - 0.17 11.8 1.3 2.5 8.1 0.6 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 PFH37088.1 - 1 9.5 6.7 3.8 7.8 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH37088.1 - 1.1 10.1 3.2 47 4.9 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat SSP160 PF06933.11 PFH37089.1 - 0.12 10.5 9.7 0.23 9.6 9.7 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 PFH37089.1 - 0.77 9.7 16.1 1.8 8.6 16.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 PFH37089.1 - 0.82 9.7 21.9 0.052 13.5 14.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.12 PFH37089.1 - 6.3 4.7 6.5 8.5 4.2 6.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CAF1A PF12253.8 PFH37090.1 - 0.00088 19.4 10.9 0.00088 19.4 10.9 4.4 5 0 0 5 5 5 1 Chromatin assembly factor 1 subunit A DUF2151 PF10221.9 PFH37090.1 - 3.3 6.2 14.2 7.5 5.0 14.2 1.5 1 0 0 1 1 1 0 Cell cycle and development regulator DUF262 PF03235.14 PFH37090.1 - 3.4 7.8 8.5 8.7 6.4 8.5 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF572 PF04502.13 PFH37090.1 - 3.9 7.0 37.0 1.7 8.2 19.8 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF572) DnaJ PF00226.31 PFH37092.1 - 2e-27 95.1 0.9 3.4e-27 94.4 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain Tfb2 PF03849.14 PFH37093.1 - 2.8e-41 141.7 0.0 4.8e-30 104.7 0.0 4.8 4 1 0 4 4 4 4 Transcription factor Tfb2 Helicase_C_3 PF13625.6 PFH37093.1 - 0.0007 19.7 0.1 0.0018 18.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Tfb2_C PF18307.1 PFH37093.1 - 0.0042 17.5 0.4 0.0088 16.5 0.4 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain SNAP PF14938.6 PFH37094.1 - 0.04 13.3 0.0 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Ank_5 PF13857.6 PFH37095.1 - 5.3e-21 74.4 0.6 4.7e-08 33.1 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PFH37095.1 - 1.7e-19 70.2 0.3 8.6e-14 51.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PFH37095.1 - 3.7e-17 60.7 0.4 7.6e-06 25.9 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 PFH37095.1 - 5.7e-16 58.2 6.5 2.4e-07 30.9 0.1 4.2 2 2 1 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 PFH37095.1 - 1.8e-15 57.1 3.3 8.4e-11 42.2 0.3 3.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) WRNPLPNID PF15017.6 PFH37095.1 - 0.14 13.1 0.2 0.14 13.1 0.2 3.7 2 2 1 3 3 3 0 Putative WW-binding domain and destruction box Peptidase_M16_C PF05193.21 PFH37096.1 - 4e-09 36.7 0.0 2.1e-05 24.7 0.0 3.9 3 1 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PFH37096.1 - 6.7e-08 32.6 0.1 1.5e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) TFIIA PF03153.13 PFH37096.1 - 0.61 10.0 8.7 1.4 8.8 8.7 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 PFH37096.1 - 1.5 8.4 15.8 0.11 12.3 10.5 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 PFH37096.1 - 1.6 7.8 28.7 3.4 6.7 28.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.11 PFH37096.1 - 5.5 6.5 14.1 0.57 9.7 9.7 1.5 2 0 0 2 2 2 0 PPP4R2 Nop14 PF04147.12 PFH37096.1 - 9.3 4.3 16.4 16 3.6 16.4 1.2 1 0 0 1 1 1 0 Nop14-like family Rep_fac-A_3 PF08661.11 PFH37097.1 - 0.00016 22.0 0.0 0.00022 21.5 0.0 1.2 1 0 0 1 1 1 1 Replication factor A protein 3 Peptidase_C48 PF02902.19 PFH37098.1 - 2.7e-37 128.7 0.8 4.1e-37 128.1 0.8 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain ACPS PF01648.20 PFH37100.1 - 4.6e-08 33.2 0.0 9.5e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF4574 PF15141.6 PFH37101.1 - 0.0066 16.3 0.0 0.0081 16.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF543 PF04418.12 PFH37101.1 - 0.056 13.4 0.3 0.098 12.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Sugar_tr PF00083.24 PFH37102.1 - 4.2e-72 243.5 18.0 5.3e-72 243.1 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PFH37102.1 - 1.7e-27 96.3 25.2 1.7e-27 96.3 25.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 PFH37102.1 - 0.00025 19.5 3.0 0.00025 19.5 3.0 2.2 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family YchF-GTPase_C PF06071.13 PFH37104.1 - 1.6e-41 140.3 0.2 4e-41 139.1 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 PFH37104.1 - 3e-21 75.6 0.0 1.2e-20 73.7 0.0 1.9 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PFH37104.1 - 1.4e-06 27.9 0.0 3.6e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA PF00004.29 PFH37104.1 - 0.0061 17.0 0.0 0.26 11.7 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TGS PF02824.21 PFH37104.1 - 0.0069 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain Roc PF08477.13 PFH37104.1 - 0.017 15.4 0.1 1.6 8.9 0.0 2.7 2 2 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 PFH37104.1 - 0.23 10.4 0.6 0.64 9.0 0.0 2.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Nop53 PF07767.11 PFH37105.1 - 3.3 7.0 14.3 5.6 6.3 14.3 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DnaJ PF00226.31 PFH37106.1 - 3.5e-06 27.1 0.7 6.2e-05 23.1 0.0 2.9 4 0 0 4 4 4 1 DnaJ domain Sugar_tr PF00083.24 PFH37107.1 - 7.3e-84 282.2 25.0 8.4e-84 282.0 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PFH37107.1 - 5.2e-30 104.6 24.6 1.8e-22 79.8 2.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 PFH37107.1 - 1.4e-09 37.0 1.4 1.4e-09 37.0 1.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Evr1_Alr PF04777.13 PFH37108.1 - 0.023 15.1 0.0 0.035 14.6 0.0 1.3 1 0 0 1 1 1 0 Erv1 / Alr family Ephrin_rec_like PF07699.13 PFH37110.1 - 8.6e-07 28.6 18.2 1.5e-06 27.9 3.2 3.4 3 1 1 4 4 4 2 Putative ephrin-receptor like CreD PF06123.12 PFH37110.1 - 5.8 5.6 8.9 14 4.4 8.0 1.8 2 0 0 2 2 2 0 Inner membrane protein CreD DJ-1_PfpI PF01965.24 PFH37111.1 - 1.4e-38 132.3 0.4 1.6e-38 132.1 0.4 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family PAPS_reduct PF01507.19 PFH37112.1 - 1.1e-16 61.3 0.0 1.8e-11 44.4 0.0 3.2 2 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family GTP_EFTU PF00009.27 PFH37113.1 - 1.2e-32 113.0 0.0 1.2e-32 113.0 0.0 3.2 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PFH37113.1 - 2.1e-19 69.6 0.1 6.7e-19 68.0 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 PFH37113.1 - 5.2e-14 51.9 0.2 1.7e-13 50.2 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 PFH37113.1 - 3.6e-13 49.7 3.5 4.4e-08 33.4 0.1 3.7 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PFH37113.1 - 1.1e-07 31.9 0.0 1.1e-06 28.7 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 PFH37113.1 - 0.00012 22.3 0.0 0.00033 20.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PPDK_N PF01326.19 PFH37114.1 - 3.2e-17 62.8 0.0 3.3e-13 49.6 0.0 3.2 2 1 1 3 3 3 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Efg1 PF10153.9 PFH37114.1 - 0.01 16.2 1.5 0.054 13.9 1.5 2.2 1 0 0 1 1 1 0 rRNA-processing protein Efg1 DNA_pol_B_N PF18094.1 PFH37114.1 - 0.12 13.0 0.0 0.38 11.3 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase beta N-terminal domain Bromodomain PF00439.25 PFH37117.1 - 1.4e-14 54.0 0.0 2.5e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Dopey_N PF04118.14 PFH37119.1 - 2.1e-83 280.0 0.0 4.8e-83 278.8 0.0 1.6 1 0 0 1 1 1 1 Dopey, N-terminal DNA_meth_N PF18284.1 PFH37120.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 DNA methylase N-terminal domain DKCLD PF08068.12 PFH37121.1 - 9.7e-32 108.8 0.1 5.7e-31 106.4 0.1 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 PFH37121.1 - 1.7e-22 79.3 1.6 3.2e-22 78.4 1.6 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 PFH37121.1 - 3.9e-22 79.2 5.3 2.4e-20 73.4 0.2 3.7 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 PFH37121.1 - 1.9e-21 75.8 1.2 4.1e-21 74.7 1.2 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 PFH37121.1 - 0.0036 17.5 0.1 0.0084 16.3 0.1 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain DUF4746 PF15928.5 PFH37121.1 - 6.5 6.1 13.6 9.3 5.6 13.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) WD40 PF00400.32 PFH37122.1 - 2.7e-20 72.3 4.6 0.0014 19.4 0.0 9.7 9 1 0 9 9 9 3 WD domain, G-beta repeat Utp13 PF08625.11 PFH37122.1 - 3.5e-14 52.9 0.0 8e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 PFH37122.1 - 3e-09 37.1 0.2 0.17 12.2 0.0 5.7 5 1 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 PFH37122.1 - 0.0069 15.1 0.0 0.015 13.9 0.0 1.6 1 0 0 1 1 1 1 beta-propeller of ELYS nucleoporin Nup160 PF11715.8 PFH37122.1 - 0.019 13.6 0.0 0.046 12.4 0.0 1.6 1 0 0 1 1 1 0 Nucleoporin Nup120/160 SAPS PF04499.15 PFH37122.1 - 3.9 6.1 5.0 5.9 5.6 5.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 PFH37122.1 - 5.3 5.2 13.2 7.7 4.7 13.2 1.3 1 0 0 1 1 1 0 CDC45-like protein SAG PF04092.13 PFH37123.1 - 3.5e-09 37.5 6.2 1.5e-06 29.0 1.7 2.3 2 0 0 2 2 2 2 SRS domain ENTH PF01417.20 PFH37124.1 - 2.6e-33 114.7 0.0 3.8e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 ENTH domain Med19 PF10278.9 PFH37124.1 - 8 6.4 9.7 15 5.5 9.7 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 PPTA PF01239.22 PFH37125.1 - 5.8e-13 48.1 16.3 5.1e-05 22.8 0.0 5.6 6 0 0 6 6 6 3 Protein prenyltransferase alpha subunit repeat LRR_4 PF12799.7 PFH37125.1 - 2.3e-05 24.7 1.6 0.00046 20.5 0.3 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH37125.1 - 0.00011 21.9 1.9 0.00053 19.7 0.6 2.4 1 1 1 2 2 2 2 Leucine rich repeat Hamartin PF04388.12 PFH37125.1 - 3.3 6.3 21.2 0.12 11.1 15.1 1.7 2 0 0 2 2 2 0 Hamartin protein Tim17 PF02466.19 PFH37126.1 - 3.2e-09 37.1 0.8 6.8e-09 36.1 0.8 1.6 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sigma70_r1_1 PF03979.14 PFH37127.1 - 0.076 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 PBC PF03792.13 PFH37127.1 - 0.15 11.8 1.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 PBC domain Atg14 PF10186.9 PFH37129.1 - 0.023 13.8 0.0 0.056 12.5 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Yip1 PF04893.17 PFH37130.1 - 1.9e-07 31.0 13.5 3.3e-07 30.2 13.5 1.4 1 0 0 1 1 1 1 Yip1 domain EptA_B_N PF08019.12 PFH37130.1 - 0.034 14.0 2.7 0.065 13.1 2.7 1.4 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB NFACT-R_1 PF05670.13 PFH37131.1 - 7.2e-33 113.5 0.4 1.8e-31 109.0 0.0 3.1 3 0 0 3 3 3 1 NFACT protein RNA binding domain FbpA PF05833.11 PFH37131.1 - 4.5e-29 101.5 11.4 7.4e-20 71.1 0.0 3.7 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-C PF11923.8 PFH37131.1 - 6e-24 84.0 0.2 4.9e-23 81.1 0.2 2.7 1 0 0 1 1 1 1 NFACT protein C-terminal domain Arm PF00514.23 PFH37133.1 - 1.2 9.3 0.0 1.2 9.3 0.0 5.7 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PFH37133.1 - 4.2 8.0 12.0 3.5 8.2 0.0 5.4 7 0 0 7 7 7 0 HEAT-like repeat LCM PF04072.14 PFH37136.1 - 3e-28 99.0 0.3 1.3e-24 87.2 0.0 2.3 2 0 0 2 2 2 2 Leucine carboxyl methyltransferase NifU_N PF01592.16 PFH37137.1 - 4.8e-47 159.3 0.1 6.9e-47 158.8 0.1 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain GAGA PF09237.11 PFH37137.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 GAGA factor LRR19-TM PF15176.6 PFH37138.1 - 0.082 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain PADR1 PF08063.12 PFH37138.1 - 0.56 10.0 6.3 12 5.8 2.9 3.4 3 1 0 3 3 3 0 PADR1 (NUC008) domain KH_1 PF00013.29 PFH37139.1 - 6e-09 35.6 0.1 1.4e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 PFH37139.1 - 0.059 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 KH domain Myb_DNA-bind_7 PF15963.5 PFH37141.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Myb DNA-binding like PP2C PF00481.21 PFH37143.1 - 6.1e-43 147.3 0.0 1e-42 146.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PFH37143.1 - 0.0013 18.7 0.0 0.0087 16.0 0.0 2.3 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) EF-hand_6 PF13405.6 PFH37144.1 - 1.2e-13 49.8 5.0 2e-08 33.5 0.2 4.9 5 1 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 PFH37144.1 - 1.3e-13 51.2 2.6 2.4e-08 34.3 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PFH37144.1 - 6e-12 44.2 8.0 1.4e-07 30.5 0.2 5.2 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 PFH37144.1 - 8.8e-10 38.3 2.5 0.055 13.3 0.0 4.9 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 PFH37144.1 - 0.0024 18.1 0.0 0.016 15.5 0.0 2.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 PFH37144.1 - 0.0026 17.2 0.2 0.0026 17.2 0.2 4.0 5 0 0 5 5 5 1 EF hand Metal_resist PF13801.6 PFH37144.1 - 0.016 15.4 0.5 0.12 12.5 0.1 2.3 1 1 1 2 2 2 0 Heavy-metal resistance PelD_GGDEF PF16963.5 PFH37144.1 - 0.021 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 PelD GGDEF domain EF-hand_14 PF17959.1 PFH37144.1 - 0.076 13.4 0.0 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain ERAP1_C PF11838.8 PFH37144.1 - 0.092 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 ERAP1-like C-terminal domain SurA_N_2 PF13623.6 PFH37144.1 - 0.15 11.9 0.2 3.4 7.5 0.0 2.3 2 1 1 3 3 3 0 SurA N-terminal domain IMS PF00817.20 PFH37145.1 - 1.6e-29 102.9 0.0 3.1e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family BRCT_2 PF16589.5 PFH37145.1 - 5.3e-12 46.0 0.0 1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 PFH37145.1 - 1.8e-05 24.8 0.0 4.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif BRCT PF00533.26 PFH37145.1 - 0.0014 19.0 0.1 0.0027 18.0 0.1 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DER1 PF04511.15 PFH37146.1 - 4.8e-20 72.3 0.0 3.3e-11 43.5 0.0 3.2 3 0 0 3 3 3 3 Der1-like family CAP PF00188.26 PFH37147.1 - 2.1e-05 25.4 0.7 4.5e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Cysteine-rich secretory protein family AP2 PF00847.20 PFH37149.1 - 0.00013 22.1 7.7 0.007 16.6 0.8 2.5 2 0 0 2 2 2 2 AP2 domain PP2C PF00481.21 PFH37151.1 - 2.1e-23 83.3 0.1 3.9e-16 59.5 0.0 3.6 4 0 0 4 4 4 2 Protein phosphatase 2C SpoIIE PF07228.12 PFH37151.1 - 0.013 15.4 0.1 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) LRR_6 PF13516.6 PFH37152.1 - 0.005 16.8 0.1 0.35 11.0 0.0 2.9 3 0 0 3 3 3 1 Leucine Rich repeat TLD PF07534.16 PFH37153.1 - 2.5e-23 82.8 0.0 4e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 PFH37153.1 - 7.1e-15 55.2 0.0 1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TT_ORF2 PF02957.15 PFH37154.1 - 3.5 8.5 7.1 5.6 7.9 1.5 2.0 1 1 1 2 2 2 0 TT viral ORF2 Ccdc124 PF06244.12 PFH37155.1 - 1.9e-39 135.2 10.2 1.9e-39 135.2 10.2 2.3 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 PFH37155.1 - 0.0008 19.8 1.2 0.0008 19.8 1.2 3.5 3 2 0 3 3 3 1 HMG (high mobility group) box CHDNT PF08073.12 PFH37155.1 - 0.017 15.1 0.5 0.029 14.3 0.5 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain Pneumo_att_G PF05539.11 PFH37155.1 - 8.5 5.9 7.0 11 5.5 7.0 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G EMP24_GP25L PF01105.24 PFH37156.1 - 3e-15 56.6 0.0 3.5e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD WGG PF10273.9 PFH37157.1 - 1.5e-15 57.6 0.1 2.8e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 MCM PF00493.23 PFH37159.1 - 8.7e-94 312.8 0.0 1.3e-93 312.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 PFH37159.1 - 1.4e-16 60.6 0.0 3.5e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 PFH37159.1 - 1.8e-16 60.2 0.2 3.3e-16 59.3 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 PFH37159.1 - 5.5e-08 32.4 0.1 0.00015 21.2 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 PFH37159.1 - 8.1e-07 29.6 3.1 3.3e-06 27.6 3.0 2.0 1 1 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 PFH37159.1 - 5.9e-06 26.3 0.0 1.6e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 PFH37159.1 - 2e-05 24.4 0.0 4.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PFH37159.1 - 0.016 15.0 0.0 0.32 10.7 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PFH37159.1 - 0.016 15.6 0.1 0.65 10.4 0.0 3.2 1 1 1 2 2 2 0 AAA ATPase domain AAA PF00004.29 PFH37159.1 - 0.028 14.9 0.1 0.46 10.9 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 PFH37159.1 - 0.068 12.9 0.0 1.2 8.8 0.0 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 PFH37159.1 - 0.098 12.2 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Zn-ribbon_8 PF09723.10 PFH37159.1 - 0.2 11.8 2.3 0.53 10.4 2.3 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Pkinase_Tyr PF07714.17 PFH37160.1 - 4.4e-43 147.4 0.0 6.4e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PFH37160.1 - 7.2e-39 133.7 0.0 1.3e-25 90.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 PFH37160.1 - 0.092 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FA_desaturase PF00487.24 PFH37161.1 - 2e-29 103.2 15.5 3e-29 102.6 15.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 PFH37161.1 - 1.2e-12 47.1 0.2 2.1e-12 46.3 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) SNO PF01174.19 PFH37163.1 - 0.19 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Sec34 PF04136.15 PFH37164.1 - 0.036 14.0 8.2 3.9 7.3 0.1 3.1 1 1 2 3 3 3 0 Sec34-like family TMF_DNA_bd PF12329.8 PFH37164.1 - 0.037 14.0 2.6 0.037 14.0 2.6 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Snapin_Pallidin PF14712.6 PFH37164.1 - 0.073 13.5 0.7 0.073 13.5 0.7 3.0 2 1 1 3 3 3 0 Snapin/Pallidin DUF4559 PF15112.6 PFH37164.1 - 0.92 9.1 8.9 1.6 8.4 8.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) DUF4446 PF14584.6 PFH37164.1 - 1.3 9.0 9.2 1.1 9.2 0.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Seryl_tRNA_N PF02403.22 PFH37164.1 - 3 8.1 12.7 9.1 6.6 1.4 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Peptidase_A22B PF04258.13 PFH37167.1 - 9e-76 255.1 8.7 1.3e-75 254.6 8.7 1.2 1 0 0 1 1 1 1 Signal peptide peptidase SOR_SNZ PF01680.17 PFH37168.1 - 8.3e-108 358.9 6.4 8.3e-108 358.9 6.4 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 PFH37168.1 - 3.8e-07 29.7 4.7 5.1e-06 26.0 0.0 2.5 2 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 PFH37168.1 - 0.00035 19.8 0.5 0.044 13.0 0.0 2.5 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.17 PFH37168.1 - 0.00098 18.3 0.0 0.85 8.7 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) FMN_dh PF01070.18 PFH37168.1 - 0.0052 15.9 0.3 0.033 13.2 0.0 2.2 2 1 0 2 2 2 1 FMN-dependent dehydrogenase OMPdecase PF00215.24 PFH37168.1 - 0.0071 16.0 0.0 0.44 10.1 0.0 2.5 1 1 1 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family NMO PF03060.15 PFH37168.1 - 0.011 15.2 2.1 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase His_biosynth PF00977.21 PFH37168.1 - 0.058 12.8 0.1 0.86 9.0 0.0 2.3 2 1 0 2 2 2 0 Histidine biosynthesis protein AAA PF00004.29 PFH37169.1 - 3.2e-16 59.9 0.0 6.4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 PFH37169.1 - 4.1e-16 59.2 0.0 9.1e-16 58.1 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 PFH37169.1 - 4.6e-11 43.0 0.0 1.5e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_30 PF13604.6 PFH37169.1 - 9.5e-07 28.7 0.0 4.1e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PFH37169.1 - 4.6e-06 26.9 0.1 6.6e-05 23.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 PFH37169.1 - 5.8e-06 26.5 0.1 8.1e-05 22.9 0.1 2.3 2 0 0 2 2 2 1 AAA C-terminal domain AAA_16 PF13191.6 PFH37169.1 - 1.1e-05 25.9 0.5 9.2e-05 22.9 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 PFH37169.1 - 5.3e-05 22.6 0.0 9.7e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 PFH37169.1 - 0.00012 21.8 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PFH37169.1 - 0.00015 21.6 0.0 0.00045 20.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 PFH37169.1 - 0.00022 21.2 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 PFH37169.1 - 0.00022 21.8 0.0 0.00087 19.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 PFH37169.1 - 0.00036 20.9 0.1 0.0029 17.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PFH37169.1 - 0.00043 20.2 0.0 0.0014 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 PFH37169.1 - 0.00071 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PFH37169.1 - 0.00081 19.4 0.1 0.0029 17.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.29 PFH37169.1 - 0.001 18.8 0.2 0.098 12.4 0.0 2.6 2 1 1 3 3 3 1 DEAD/DEAH box helicase ATPase_2 PF01637.18 PFH37169.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 PFH37169.1 - 0.0047 16.3 0.1 0.028 13.8 0.1 2.1 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI KTI12 PF08433.10 PFH37169.1 - 0.0052 16.3 0.0 0.0088 15.5 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ResIII PF04851.15 PFH37169.1 - 0.0069 16.4 0.0 0.36 10.8 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 PFH37169.1 - 0.016 15.6 0.0 0.051 14.0 0.0 1.9 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 PFH37169.1 - 0.022 14.4 0.6 0.085 12.4 0.1 2.3 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 PFH37169.1 - 0.025 13.7 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 PFH37169.1 - 0.039 13.5 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_2 PF07724.14 PFH37169.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 PFH37169.1 - 0.044 13.0 0.0 0.15 11.3 0.0 1.7 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_28 PF13521.6 PFH37169.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 PFH37169.1 - 0.045 13.2 0.3 2.2 7.7 0.0 2.3 1 1 1 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 PFH37169.1 - 0.045 13.5 0.0 0.55 9.9 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein SNF2_N PF00176.23 PFH37169.1 - 0.09 11.5 0.1 0.28 9.9 0.0 1.8 1 1 1 2 2 2 0 SNF2 family N-terminal domain TIP49_C PF17856.1 PFH37169.1 - 0.097 12.8 0.2 0.24 11.5 0.2 1.6 1 0 0 1 1 1 0 TIP49 AAA-lid domain PIF1 PF05970.14 PFH37169.1 - 0.13 11.4 0.0 1.1 8.3 0.0 2.0 1 1 0 1 1 1 0 PIF1-like helicase HTH_31 PF13560.6 PFH37169.1 - 0.32 11.4 2.4 6 7.3 0.1 3.1 3 0 0 3 3 2 0 Helix-turn-helix domain RAP PF08373.10 PFH37170.1 - 1.7e-13 50.4 0.0 3.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 PFH37170.1 - 0.0001 22.4 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 REase_MTES_1575 FAST_1 PF06743.15 PFH37170.1 - 0.0014 18.5 5.1 18 5.4 0.0 5.7 5 2 0 5 5 5 2 FAST kinase-like protein, subdomain 1 AP2 PF00847.20 PFH37171.1 - 0.00047 20.3 1.7 0.00047 20.3 1.7 2.4 2 0 0 2 2 2 1 AP2 domain DUF3328 PF11807.8 PFH37172.1 - 3.7 7.3 4.2 2.4 7.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DUF3432 PF11914.8 PFH37174.1 - 0.0039 17.4 6.5 0.041 14.1 0.7 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF3432) EIIBC-GUT_N PF03612.14 PFH37174.1 - 3 7.5 11.5 3.6 7.3 1.1 2.5 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF1298 PF06974.13 PFH37176.1 - 8e-20 71.3 0.0 1.5e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 PFH37176.1 - 0.013 15.3 1.2 0.92 9.2 0.0 3.8 3 0 0 3 3 3 0 Wax ester synthase-like Acyl-CoA acyltransferase domain RNase_T PF00929.24 PFH37177.1 - 7.6e-09 36.3 0.0 1.2e-08 35.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease SapA PF02199.15 PFH37177.1 - 0.082 13.2 2.0 0.2 12.0 2.0 1.6 1 0 0 1 1 1 0 Saposin A-type domain RALF PF05498.11 PFH37177.1 - 0.88 10.6 3.7 6.7 7.8 0.1 3.2 3 0 0 3 3 3 0 Rapid ALkalinization Factor (RALF) RAP PF08373.10 PFH37179.1 - 2.8e-05 24.1 0.0 5.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.15 PFH37179.1 - 0.1 12.6 0.2 60 3.7 0.1 4.2 3 3 3 6 6 6 0 FAST kinase-like protein, subdomain 1 CRAL_TRIO PF00650.20 PFH37180.1 - 1.1e-30 106.4 0.0 1.6e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PFH37180.1 - 6.5e-07 29.6 0.1 9.1e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PFH37180.1 - 0.012 15.8 0.1 0.042 14.0 0.0 2.0 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain ketoacyl-synt PF00109.26 PFH37181.1 - 7.5e-85 284.5 5.1 2.1e-62 211.0 1.7 2.5 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 PFH37181.1 - 1.3e-69 234.8 0.0 2.7e-69 233.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Ketoacyl-synt_C PF02801.22 PFH37181.1 - 6e-41 139.2 0.0 7.6e-32 109.8 0.0 2.8 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 PFH37181.1 - 1e-28 100.4 0.0 1.3e-26 93.6 0.0 2.6 2 0 0 2 2 2 1 KR domain PP-binding PF00550.25 PFH37181.1 - 3e-25 88.4 2.2 3.9e-13 49.6 0.2 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short PF00106.25 PFH37181.1 - 0.021 14.3 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Thiolase_N PF00108.23 PFH37181.1 - 0.022 14.1 0.1 0.06 12.7 0.1 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain Spt5-NGN PF03439.13 PFH37181.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section Tir_receptor_C PF07489.11 PFH37181.1 - 0.054 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus AMP-binding_C_2 PF14535.6 PFH37181.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain SNF2_N PF00176.23 PFH37185.1 - 4e-51 173.8 0.0 4e-51 173.8 0.0 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain PHD PF00628.29 PFH37185.1 - 6.8e-21 73.9 75.1 5.7e-09 35.7 7.0 7.0 6 1 0 6 6 6 4 PHD-finger Helicase_C PF00271.31 PFH37185.1 - 1.7e-14 54.1 0.0 5.2e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH37185.1 - 7.9e-11 42.3 4.0 1.2e-07 31.9 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit C1_1 PF00130.22 PFH37185.1 - 0.0062 16.4 1.9 0.0062 16.4 1.9 7.2 6 1 0 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 PFH37185.1 - 0.0063 16.6 5.3 0.0063 16.6 5.3 6.4 5 1 0 5 5 5 4 PHD-finger AAA_14 PF13173.6 PFH37185.1 - 0.01 15.9 0.0 0.035 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain zf-PHD-like PF15446.6 PFH37185.1 - 0.038 13.6 0.0 0.038 13.6 0.0 6.9 4 2 1 5 5 5 0 PHD/FYVE-zinc-finger like domain Rubredoxin PF00301.20 PFH37185.1 - 1.9 8.6 16.5 1.5 8.9 1.2 4.0 3 0 0 3 3 3 0 Rubredoxin MFS_1 PF07690.16 PFH37186.1 - 3.3e-28 98.6 32.2 3.3e-28 98.6 32.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PFH37186.1 - 3.7e-09 36.0 26.0 3.5e-06 26.1 15.3 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 PFH37186.1 - 0.0019 17.1 10.0 0.0098 14.8 6.9 2.7 2 2 0 2 2 2 1 MFS_1 like family Transgly_assoc PF04226.13 PFH37186.1 - 0.01 16.1 8.6 0.44 10.8 0.2 3.2 2 0 0 2 2 2 0 Transglycosylase associated protein OATP PF03137.20 PFH37186.1 - 0.016 13.5 15.2 0.055 11.7 0.5 3.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.8 PFH37186.1 - 0.034 12.8 6.8 0.063 11.9 6.8 1.4 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Gly-zipper_Omp PF13488.6 PFH37186.1 - 0.052 13.6 3.7 1.6 8.8 0.1 2.5 2 0 0 2 2 2 0 Glycine zipper NVEALA PF14055.6 PFH37186.1 - 0.052 13.5 0.3 0.13 12.3 0.3 1.6 1 0 0 1 1 1 0 NVEALA protein DSS1_SEM1 PF05160.13 PFH37190.1 - 3.5e-06 27.0 22.1 0.00017 21.6 22.1 2.2 1 1 0 1 1 1 1 DSS1/SEM1 family DUF4404 PF14357.6 PFH37190.1 - 0.072 13.7 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Packaging_FI PF14000.6 PFH37190.1 - 0.43 11.0 2.2 0.47 10.9 0.9 1.6 1 1 1 2 2 2 0 DNA packaging protein FI zf-CCCH PF00642.24 PFH37191.1 - 5.1e-11 42.2 13.7 1.3e-05 24.9 1.9 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PFH37191.1 - 1.1e-05 25.3 14.9 0.0075 16.3 5.7 2.5 2 1 0 2 2 2 2 Zinc finger domain Torus PF16131.5 PFH37191.1 - 4.2e-05 24.2 2.2 0.13 13.0 0.2 2.5 2 0 0 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 PFH37191.1 - 0.0092 16.2 1.9 1.6 9.0 0.2 2.2 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 PFH37191.1 - 0.73 9.7 16.2 2.1 8.2 6.6 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger Herpes_LMP2 PF07415.11 PFH37192.1 - 0.18 10.6 4.7 0.11 11.3 1.5 1.9 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein E1-E2_ATPase PF00122.20 PFH37193.1 - 5.6e-17 61.8 0.0 2e-15 56.8 0.0 3.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 PFH37193.1 - 4.1e-15 56.6 0.6 8.4e-08 32.8 0.5 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PFH37193.1 - 0.0054 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) zf-C2HC_2 PF13913.6 PFH37194.1 - 4.9e-12 45.4 7.3 5.3e-08 32.6 0.5 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type FYVE PF01363.21 PFH37194.1 - 0.042 14.0 1.7 11 6.2 0.3 2.7 2 0 0 2 2 2 0 FYVE zinc finger DUF2868 PF11067.8 PFH37194.1 - 0.09 12.3 3.5 0.39 10.2 3.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) zf-C2H2_4 PF13894.6 PFH37194.1 - 2.6 9.1 4.3 11 7.2 1.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DFRP_C PF16543.5 PFH37195.1 - 3.9e-18 65.7 0.3 3.9e-18 65.7 0.3 4.6 3 2 2 5 5 5 1 DRG Family Regulatory Proteins, Tma46 ZapD PF07072.11 PFH37195.1 - 0.0086 15.8 0.3 0.054 13.2 0.0 2.2 2 0 0 2 2 2 1 Cell division protein GRIP PF01465.20 PFH37197.1 - 0.092 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 GRIP domain SAPS PF04499.15 PFH37197.1 - 0.13 11.0 3.0 0.19 10.5 3.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HisKA PF00512.25 PFH37198.1 - 0.59 10.2 4.1 17 5.5 0.0 3.2 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Z1 PF10593.9 PFH37198.1 - 0.97 8.9 3.8 0.47 9.9 1.3 1.7 2 0 0 2 2 2 0 Z1 domain I_LWEQ PF01608.17 PFH37198.1 - 2.4 8.4 13.2 0.42 10.8 1.7 2.4 2 0 0 2 2 2 0 I/LWEQ domain DUF1664 PF07889.12 PFH37198.1 - 4.8 7.2 5.6 3.2 7.8 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PDDEXK_6 PF04720.12 PFH37198.1 - 8.1 6.3 10.8 0.44 10.5 2.5 2.6 1 1 1 2 2 2 0 PDDEXK-like family of unknown function zf-RING_UBOX PF13445.6 PFH37199.1 - 1.4e-05 25.0 1.1 1.4e-05 25.0 1.1 3.2 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PFH37199.1 - 1.9e-05 24.4 0.8 1.9e-05 24.4 0.8 2.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH37199.1 - 0.00018 21.4 3.8 0.00018 21.4 3.8 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 PFH37199.1 - 0.00031 21.0 5.0 0.00031 21.0 5.0 3.2 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 PFH37199.1 - 0.0039 17.0 1.9 0.0039 17.0 1.9 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PFH37199.1 - 0.47 10.6 10.3 0.047 13.9 4.4 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PFH37199.1 - 0.48 10.7 4.9 2.9 8.3 4.9 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain FYVE PF01363.21 PFH37199.1 - 0.72 10.0 4.6 6.9 6.9 2.4 2.8 2 0 0 2 2 2 0 FYVE zinc finger START PF01852.19 PFH37202.1 - 6.5e-12 45.3 0.1 1.4e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 START domain DEAD PF00270.29 PFH37203.1 - 2.4e-47 161.0 0.0 3.8e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH37203.1 - 2.1e-30 105.3 0.0 1.2e-29 102.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH37203.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PFH37203.1 - 0.00095 19.5 0.0 0.2 12.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain zf-RING_2 PF13639.6 PFH37204.1 - 4e-12 46.2 10.8 1e-11 44.9 10.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PFH37204.1 - 8.5e-08 31.8 11.1 8.5e-08 31.8 11.1 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PFH37204.1 - 3e-07 30.2 10.6 3e-07 30.2 10.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PFH37204.1 - 6.6e-07 29.5 11.0 2.1e-06 27.9 11.0 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PFH37204.1 - 3.7e-06 26.7 10.4 8.1e-06 25.6 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PFH37204.1 - 0.00041 20.1 7.2 0.00087 19.1 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH37204.1 - 0.0017 18.3 8.8 0.0034 17.3 8.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PFH37204.1 - 0.0026 17.8 9.7 0.0065 16.5 9.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 PFH37204.1 - 0.0054 16.8 2.1 0.013 15.5 2.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 PFH37204.1 - 0.087 12.5 7.7 0.21 11.3 7.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 PFH37204.1 - 0.48 10.3 10.6 0.27 11.1 8.1 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 PFH37204.1 - 1.1 9.4 7.8 3.4 7.9 7.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 PFH37204.1 - 3 8.0 13.8 0.95 9.6 10.0 2.1 2 0 0 2 2 2 0 RING-variant domain Pkinase PF00069.25 PFH37206.1 - 1.1e-07 31.5 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH37206.1 - 4.3e-05 22.9 0.0 7.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH37206.1 - 0.0092 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF1664 PF07889.12 PFH37206.1 - 0.048 13.7 0.2 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ank_4 PF13637.6 PFH37207.1 - 4.5e-17 62.2 0.8 1e-08 35.5 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PFH37207.1 - 9.1e-16 57.7 1.7 1.7e-05 25.0 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PFH37207.1 - 1.9e-14 54.0 0.2 3.3e-08 34.0 0.0 3.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PFH37207.1 - 3.1e-12 45.5 0.7 0.032 14.8 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 PFH37207.1 - 1.1e-09 38.3 6.1 0.00053 20.3 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat DUF1843 PF08898.10 PFH37207.1 - 0.032 14.7 0.2 0.15 12.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Ribosomal_L7Ae PF01248.26 PFH37208.1 - 9e-27 92.7 0.1 1.2e-26 92.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 PFH37208.1 - 0.0049 16.7 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 PFH37208.1 - 0.013 15.6 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 Lysine_decarbox PF03641.14 PFH37209.1 - 1.7e-22 79.9 0.0 3.1e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 PFH37209.1 - 2.2e-06 27.3 0.0 3.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 SLOG cluster4 family Retrotrans_gag PF03732.17 PFH37209.1 - 0.0048 17.1 0.1 0.0093 16.2 0.1 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein RRM_1 PF00076.22 PFH37212.1 - 1.6e-22 79.1 0.0 6.8e-07 29.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH37212.1 - 0.064 13.4 0.0 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif Cullin_binding PF03556.15 PFH37213.1 - 2.4e-28 99.0 0.1 3.7e-28 98.4 0.1 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 PFH37213.1 - 3e-11 43.0 0.0 6e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain TMEM65 PF10507.9 PFH37215.1 - 3.7e-38 129.8 0.1 7.4e-38 128.9 0.1 1.5 1 0 0 1 1 1 1 Transmembrane protein 65 GAF_2 PF13185.6 PFH37215.1 - 3.6e-07 30.5 0.1 6.1e-06 26.6 0.0 2.6 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 PFH37215.1 - 5.4e-07 30.3 0.0 5.8e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 PFH37215.1 - 0.0083 16.5 0.5 0.17 12.2 0.0 3.0 3 0 0 3 3 3 1 GAF domain DUF5136 PF17199.4 PFH37218.1 - 0.85 9.4 3.6 2.6 7.8 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF5136) TBP PF00352.21 PFH37219.1 - 5.9e-10 39.0 0.0 0.00071 19.5 0.0 2.6 3 0 0 3 3 3 2 Transcription factor TFIID (or TATA-binding protein, TBP) RunxI PF08504.11 PFH37219.1 - 0.02 15.6 4.4 0.045 14.5 0.5 2.6 2 0 0 2 2 2 0 Runx inhibition domain TFIIIC_delta PF12657.7 PFH37219.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term zf-C3HC4 PF00097.25 PFH37220.1 - 0.0016 18.3 8.4 0.0028 17.5 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH37220.1 - 0.019 14.9 9.1 0.035 14.1 9.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 PFH37220.1 - 0.049 13.5 6.5 0.11 12.4 6.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zinc-ribbons_6 PF07191.12 PFH37220.1 - 0.19 11.7 7.1 0.34 10.9 7.1 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-C3HC4_2 PF13923.6 PFH37220.1 - 0.28 11.0 8.8 0.54 10.2 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH37220.1 - 2.4 8.3 6.9 5.6 7.1 6.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger PP2C PF00481.21 PFH37221.1 - 2e-41 142.3 3.8 3.6e-34 118.6 0.9 3.5 3 0 0 3 3 3 2 Protein phosphatase 2C RCC1 PF00415.18 PFH37222.1 - 2.1e-30 105.1 13.4 3.8e-08 33.8 0.0 8.9 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH37222.1 - 3.9e-20 71.1 24.6 1.7e-05 24.5 0.4 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 PFH37223.1 - 1.9e-38 132.3 0.0 2.9e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH37223.1 - 1.8e-17 63.5 0.0 2.6e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH37223.1 - 0.0019 17.5 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 2 Kinase-like MAP17 PF15807.5 PFH37223.1 - 5.7 7.2 5.8 13 6.0 5.8 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PCI PF01399.27 PFH37224.1 - 3.4e-08 33.9 0.0 1.4e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.6 PFH37224.1 - 0.001 19.6 2.1 0.001 19.6 2.1 5.2 5 1 1 6 6 6 2 Tetratricopeptide repeat RPN6_N PF18055.1 PFH37224.1 - 0.029 14.7 0.3 0.11 12.8 0.3 2.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_7 PF13176.6 PFH37224.1 - 0.057 13.5 3.6 3.9 7.7 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH37224.1 - 0.26 12.0 9.2 87 4.1 0.1 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M16 PF00675.20 PFH37225.1 - 5.6e-52 175.7 0.3 2.3e-51 173.7 0.2 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PFH37225.1 - 8.4e-31 107.4 0.0 5.5e-30 104.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain DNA_mis_repair PF01119.19 PFH37226.1 - 1.9e-15 56.6 0.0 2.9e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 PFH37226.1 - 4e-11 42.9 0.0 1.2e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 PFH37226.1 - 2.3e-08 34.0 0.0 4.8e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PFH37226.1 - 4.6e-07 30.3 0.0 1.1e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ni_hydr_CYTB PF01292.20 PFH37228.1 - 0.0089 15.6 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 AAA_22 PF13401.6 PFH37229.1 - 0.008 16.5 0.0 0.12 12.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.25 PFH37229.1 - 0.021 14.5 0.1 7.1 6.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 PFH37229.1 - 0.13 12.1 0.1 1.1 9.2 0.0 2.4 3 0 0 3 3 3 0 NACHT domain SRP9-21 PF05486.12 PFH37230.1 - 4.4e-08 33.4 0.4 2e-06 28.1 0.4 2.2 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Chalcone PF02431.15 PFH37230.1 - 0.057 12.8 0.0 0.065 12.6 0.0 1.1 1 0 0 1 1 1 0 Chalcone-flavanone isomerase Trypan_PARP PF05887.11 PFH37231.1 - 0.17 11.8 16.3 0.43 10.5 16.3 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Autophagy_N PF03986.13 PFH37232.1 - 6.9e-31 107.0 0.0 1.4e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 PFH37232.1 - 1.3e-20 73.7 0.2 2.7e-20 72.7 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 PFH37232.1 - 3.6e-13 48.7 1.4 6.5e-13 47.9 1.4 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Rep_fac-A_C PF08646.10 PFH37233.1 - 6.8e-27 94.0 2.2 1.9e-26 92.5 0.9 2.1 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 PFH37233.1 - 3.5e-23 81.3 0.0 8.2e-21 73.8 0.0 3.1 3 0 0 3 3 3 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 PFH37233.1 - 7.5e-12 45.1 0.0 1.1e-08 34.9 0.1 2.8 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 PFH37233.1 - 2.4e-05 24.2 0.7 0.033 13.9 1.6 2.3 2 0 0 2 2 2 2 Cell division control protein 24, OB domain 3 DUF4539 PF15072.6 PFH37233.1 - 2.5e-05 24.2 0.0 1.1 9.4 0.0 3.7 4 0 0 4 4 4 2 Domain of unknown function (DUF4539) tRNA_anti_2 PF13742.6 PFH37233.1 - 0.0094 16.1 0.0 0.096 12.9 0.0 2.4 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain zf-UBR PF02207.20 PFH37233.1 - 0.17 12.1 4.3 0.36 11.0 4.3 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF4503 PF14951.6 PFH37233.1 - 1.3 7.4 7.0 2.5 6.5 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) P5CR_dimer PF14748.6 PFH37234.1 - 3.8e-36 123.4 0.3 7.6e-36 122.5 0.3 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 PFH37234.1 - 9.3e-12 45.4 0.1 1.7e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 PFH37234.1 - 0.0076 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Glycolytic PF00274.19 PFH37236.1 - 5.5e-170 564.7 0.0 6.3e-170 564.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Trp_halogenase PF04820.14 PFH37236.1 - 0.091 11.6 0.0 0.2 10.5 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase Glycolytic PF00274.19 PFH37237.1 - 1.7e-167 556.5 0.0 1.9e-167 556.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DUF775 PF05603.12 PFH37238.1 - 3.8e-23 82.1 0.1 4.8e-21 75.2 0.1 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Prenylcys_lyase PF07156.14 PFH37239.1 - 4.8e-30 104.9 0.0 1.5e-29 103.2 0.0 1.7 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 PFH37239.1 - 2.1e-06 27.8 2.2 1.2e-05 25.4 2.2 2.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 PFH37239.1 - 1.1e-05 25.0 0.0 0.00031 20.2 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 PFH37239.1 - 0.003 17.2 0.1 0.0063 16.1 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PFH37239.1 - 0.0096 15.2 0.1 0.028 13.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2 PF00111.27 PFH37240.1 - 4.8e-11 42.5 1.3 8.6e-11 41.6 1.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MIF4G PF02854.19 PFH37241.1 - 0.03 14.0 0.0 4.1 7.0 0.0 2.9 2 0 0 2 2 2 0 MIF4G domain IBR PF01485.21 PFH37242.1 - 2.2e-21 75.8 22.7 5.4e-09 36.1 10.8 4.7 4 1 0 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 PFH37242.1 - 0.046 13.6 0.0 0.046 13.6 0.0 4.4 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) PaaA_PaaC PF05138.12 PFH37242.1 - 0.064 12.4 2.3 0.15 11.2 0.1 2.1 2 0 0 2 2 2 0 Phenylacetic acid catabolic protein zf-C3HC4_4 PF15227.6 PFH37242.1 - 0.13 12.4 20.0 4 7.7 8.9 4.0 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PFH37242.1 - 0.13 12.5 13.8 6.6 7.1 10.3 2.8 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PFH37242.1 - 0.16 11.9 0.1 0.16 11.9 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PFH37242.1 - 1.8 9.0 27.3 1.1 9.6 0.5 3.6 3 0 0 3 3 3 0 Ring finger domain TRAF6_Z2 PF18048.1 PFH37242.1 - 6.5 6.9 8.1 19 5.5 8.1 1.8 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 eIF2_C PF09173.11 PFH37243.1 - 1.2e-34 118.3 0.3 2.8e-34 117.2 0.1 1.8 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 PFH37243.1 - 6.3e-23 81.3 0.1 8.4e-22 77.7 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PFH37243.1 - 2.7e-11 43.7 3.1 3.4e-11 43.4 0.8 2.4 2 1 1 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PFH37243.1 - 0.0066 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PFH37243.1 - 0.0095 15.8 0.1 0.065 13.1 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase SAG PF04092.13 PFH37244.1 - 3.5e-15 56.9 7.7 3.3e-10 40.9 0.6 2.5 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37245.1 - 3.5e-10 40.8 1.5 5.1e-10 40.3 1.5 1.2 1 0 0 1 1 1 1 SRS domain Methyltransf_16 PF10294.9 PFH37246.1 - 1.9e-12 47.3 0.0 8.4e-05 22.4 0.0 3.2 3 0 0 3 3 3 3 Lysine methyltransferase Peptidase_S8 PF00082.22 PFH37247.1 - 3.7e-46 157.7 5.7 8.5e-46 156.6 5.7 1.6 1 0 0 1 1 1 1 Subtilase family KH_1 PF00013.29 PFH37248.1 - 1.3e-24 85.8 0.0 5e-07 29.5 0.0 4.2 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 PFH37248.1 - 0.0039 17.0 0.0 15 5.5 0.0 3.9 4 0 0 4 4 4 1 KH domain KH_4 PF13083.6 PFH37248.1 - 0.08 12.8 0.0 17 5.3 0.0 2.6 2 0 0 2 2 2 0 KH domain DHC_N1 PF08385.12 PFH37249.1 - 1.9e-148 495.6 7.0 1.9e-148 495.6 7.0 3.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 PFH37249.1 - 1.5e-147 490.9 0.0 2.2e-146 487.0 0.0 2.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PFH37249.1 - 1.4e-115 386.6 10.9 1.4e-115 386.6 10.9 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PFH37249.1 - 1.7e-95 319.3 0.0 1.4e-94 316.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PFH37249.1 - 2.4e-87 293.0 4.3 1e-86 290.9 0.0 3.6 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PFH37249.1 - 8.8e-76 253.9 0.1 8.8e-76 253.9 0.1 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 PFH37249.1 - 9.1e-75 250.1 0.3 6.5e-72 240.8 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 PFH37249.1 - 3.8e-54 184.0 12.0 6.9e-54 183.2 12.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 PFH37249.1 - 8.3e-53 178.6 0.0 4.7e-52 176.1 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PFH37249.1 - 5.8e-40 136.1 2.3 2.4e-37 127.7 0.0 4.2 5 0 0 5 5 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PFH37249.1 - 4.9e-27 94.5 0.9 1.9e-26 92.7 0.1 2.6 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PFH37249.1 - 3.6e-19 69.1 0.0 1.1e-06 28.7 0.0 5.4 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PFH37249.1 - 9.9e-16 57.8 0.1 9.9e-16 57.8 0.1 3.1 3 0 0 3 3 3 1 AAA+ lid domain AAA_22 PF13401.6 PFH37249.1 - 0.00036 20.8 0.1 0.65 10.3 0.0 5.0 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 PFH37249.1 - 0.0011 19.4 0.1 4.3 7.8 0.0 3.9 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 PFH37249.1 - 0.006 16.1 0.6 2.1 7.8 0.0 3.3 3 0 0 3 3 3 1 PhoH-like protein DEAD PF00270.29 PFH37249.1 - 0.021 14.6 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.6 PFH37249.1 - 0.024 15.0 8.4 4.4 7.7 0.2 6.3 5 2 0 6 6 5 0 AAA ATPase domain AAA_24 PF13479.6 PFH37249.1 - 0.2 11.3 0.7 9.8 5.8 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 PFH37249.1 - 0.24 11.1 2.8 16 5.1 0.1 3.9 4 0 0 4 4 4 0 AAA domain zf-CCCH PF00642.24 PFH37250.1 - 5.8e-10 38.8 7.1 5.6e-06 26.1 1.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PFH37250.1 - 5.7e-08 32.4 9.6 8e-06 25.5 1.3 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PFH37250.1 - 1.1e-06 28.5 7.0 0.0056 16.7 0.7 2.6 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 PFH37250.1 - 0.033 14.4 1.2 0.36 11.1 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger containing family Nab2p_Zf1 PF18260.1 PFH37250.1 - 0.033 14.1 1.7 5.1 7.1 0.1 2.5 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 zf-CCCH_2 PF14608.6 PFH37250.1 - 0.034 14.6 7.4 1.2 9.8 0.9 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 PFH37250.1 - 0.042 14.6 9.5 1.2 9.9 0.4 2.9 2 1 1 3 3 3 0 Torus domain Lustrin_cystein PF14625.6 PFH37250.1 - 2.6 8.5 5.5 1.9 9.0 0.6 2.7 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Lactamase_B_2 PF12706.7 PFH37251.1 - 1.1e-11 44.6 0.5 4.7e-11 42.6 0.3 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 PFH37251.1 - 5.3e-08 32.4 0.0 2.5e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 tRNase Z endonuclease DSPc PF00782.20 PFH37252.1 - 1.8e-08 34.3 0.0 1.6e-06 28.0 0.0 2.9 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 PFH37252.1 - 0.039 13.6 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 PFH37252.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain MPC PF03650.13 PFH37253.1 - 2.3e-34 117.8 0.9 3.6e-34 117.2 0.4 1.5 2 0 0 2 2 2 1 Mitochondrial pyruvate carriers SLATT_5 PF18160.1 PFH37253.1 - 0.025 13.9 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Peptidase_S8 PF00082.22 PFH37255.1 - 5.3e-43 147.4 0.8 9.1e-43 146.6 0.8 1.3 1 0 0 1 1 1 1 Subtilase family EGF_3 PF12947.7 PFH37255.1 - 1.2e-16 60.5 29.9 6e-05 23.1 5.7 4.5 4 0 0 4 4 4 4 EGF domain EGF_CA PF07645.15 PFH37255.1 - 2.5e-13 50.0 15.1 3.1e-08 33.7 5.9 4.9 4 1 1 5 5 5 2 Calcium-binding EGF domain cEGF PF12662.7 PFH37255.1 - 1.8e-10 40.5 26.3 5.3e-05 23.1 4.1 4.6 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PFH37255.1 - 0.00033 20.9 38.6 0.43 10.9 5.4 4.6 3 1 1 4 4 4 3 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 PFH37255.1 - 0.0016 18.5 4.5 0.0016 18.5 4.5 4.8 4 0 0 4 4 4 1 MSP1 EGF domain 1 EGF PF00008.27 PFH37255.1 - 0.36 11.2 34.1 0.32 11.3 1.9 4.9 4 1 0 4 4 4 0 EGF-like domain EB PF01683.18 PFH37255.1 - 1 9.7 35.9 0.35 11.2 3.1 4.4 2 2 2 4 4 4 0 EB module hEGF PF12661.7 PFH37255.1 - 1.4 9.6 41.4 0.4 11.4 2.8 5.9 5 1 0 5 5 5 0 Human growth factor-like EGF RANK_CRD_2 PF18278.1 PFH37255.1 - 4 7.7 7.0 31 4.8 1.0 3.4 3 0 0 3 3 3 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Pkinase PF00069.25 PFH37256.1 - 3.8e-71 239.6 0.0 4.9e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH37256.1 - 2.3e-33 115.6 0.0 2.9e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH37256.1 - 1.1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 PFH37256.1 - 0.00086 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH37256.1 - 0.0097 15.9 0.0 0.031 14.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PFH37256.1 - 0.017 13.9 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 PFH37256.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SMAP PF15477.6 PFH37257.1 - 5.1e-12 46.6 1.6 5.1e-12 46.6 1.6 3.3 3 1 0 3 3 3 1 Small acidic protein family FHA PF00498.26 PFH37257.1 - 7.2e-09 35.9 0.2 4.4e-08 33.4 0.2 2.2 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PFH37257.1 - 0.035 14.4 0.0 2.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain GREB1 PF15782.5 PFH37257.1 - 1.5 5.8 18.0 2 5.4 18.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PI3K_1B_p101 PF10486.9 PFH37257.1 - 4.9 4.8 24.5 7.4 4.2 24.5 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Rpr2 PF04032.16 PFH37259.1 - 3.1e-14 53.0 0.3 2.3e-12 47.0 0.1 2.5 2 0 0 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain RNase_P_Rpp14 PF01900.19 PFH37260.1 - 0.0015 18.8 0.0 0.0022 18.2 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family FBPase PF00316.20 PFH37261.1 - 1.8e-31 109.1 0.1 2.6e-31 108.6 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Peptidase_M16 PF00675.20 PFH37263.1 - 7.6e-20 71.4 0.1 9.4e-19 67.9 0.1 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PFH37263.1 - 4.1e-18 66.0 0.0 4e-11 43.3 0.0 3.7 3 0 0 3 3 3 3 Peptidase M16 inactive domain DUF1682 PF07946.14 PFH37265.1 - 4.9e-72 242.9 0.4 6e-72 242.6 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DRY_EERY PF09750.9 PFH37265.1 - 3.4 8.0 11.6 6.5 7.0 11.6 1.4 1 0 0 1 1 1 0 Alternative splicing regulator Mito_carr PF00153.27 PFH37266.1 - 2.5e-36 123.5 6.1 2.5e-12 46.6 0.1 5.3 4 1 0 4 4 4 4 Mitochondrial carrier protein Formyl_trans_N PF00551.19 PFH37267.1 - 9e-26 90.7 0.0 1.6e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 PFH37267.1 - 1.9e-10 40.9 0.0 0.0007 19.8 0.0 2.5 2 0 0 2 2 2 2 Formyl transferase, C-terminal domain DS PF01916.17 PFH37268.1 - 1.4e-129 431.5 0.0 1.9e-129 431.0 0.0 1.2 1 0 0 1 1 1 1 Deoxyhypusine synthase AAA PF00004.29 PFH37269.1 - 1.8e-70 235.5 0.0 6.1e-44 149.6 0.0 4.3 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PFH37269.1 - 2.4e-15 56.1 1.9 4.2e-10 39.3 0.3 3.0 2 1 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 PFH37269.1 - 8.4e-11 42.5 1.4 0.00063 20.2 1.3 5.0 2 2 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 PFH37269.1 - 3.6e-09 36.5 0.0 0.0022 17.8 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 PFH37269.1 - 9.7e-09 34.9 0.0 0.00042 19.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 PFH37269.1 - 1.8e-08 34.5 0.1 0.0071 16.3 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 PFH37269.1 - 2.7e-08 34.1 0.0 0.084 13.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 PFH37269.1 - 5.1e-06 26.0 0.2 0.11 11.9 0.0 2.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 PFH37269.1 - 3.1e-05 24.2 0.1 0.12 12.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 PFH37269.1 - 6.2e-05 22.8 0.0 0.052 13.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 PFH37269.1 - 0.00015 21.7 0.0 0.025 14.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 PFH37269.1 - 0.00015 22.0 0.0 0.27 11.5 0.0 3.4 3 1 1 4 4 4 1 AAA domain RNA_helicase PF00910.22 PFH37269.1 - 0.00022 21.5 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 PFH37269.1 - 0.00064 19.1 0.0 0.053 12.8 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 PFH37269.1 - 0.00065 19.7 0.0 0.27 11.2 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 PFH37269.1 - 0.0017 18.2 0.0 2.4 8.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 PFH37269.1 - 0.0024 18.4 0.0 0.15 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 PFH37269.1 - 0.0026 17.6 0.0 0.17 11.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 PFH37269.1 - 0.0026 17.8 0.0 1.9 8.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 PFH37269.1 - 0.003 18.1 0.0 0.23 11.9 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 PFH37269.1 - 0.0041 16.8 1.3 0.18 11.5 0.0 3.5 4 0 0 4 4 3 1 AAA domain Sigma54_activat PF00158.26 PFH37269.1 - 0.0054 16.5 0.2 1.8 8.2 0.0 3.2 4 0 0 4 4 3 1 Sigma-54 interaction domain Rad17 PF03215.15 PFH37269.1 - 0.0091 15.9 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 PFH37269.1 - 0.0092 15.5 0.0 3 7.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_17 PF13207.6 PFH37269.1 - 0.0097 16.3 0.0 0.93 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PFH37269.1 - 0.019 14.6 1.8 5.7 6.5 0.0 3.5 3 1 1 4 4 4 0 AAA domain Sigma54_activ_2 PF14532.6 PFH37269.1 - 0.019 15.1 0.0 5.6 7.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 PFH37269.1 - 0.044 14.0 1.5 3 8.1 0.0 3.2 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 PFH37269.1 - 0.11 11.7 0.0 4.1 6.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 PFH37269.1 - 0.13 11.7 0.0 2.3 7.6 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 PFH37269.1 - 0.14 12.5 0.1 2.3 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 PFH37269.1 - 0.21 10.9 0.0 26 4.1 0.0 2.4 3 0 0 3 3 2 0 KaiC ATPase_2 PF01637.18 PFH37269.1 - 0.25 11.2 0.0 43 3.9 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea SAG PF04092.13 PFH37270.1 - 1.4e-07 32.4 0.1 2.5e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 SRS domain Sec1 PF00995.23 PFH37271.1 - 2.5e-128 429.9 0.0 2.8e-128 429.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Helo_like_N PF17111.5 PFH37271.1 - 0.048 13.0 0.2 0.091 12.1 0.2 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins OTU PF02338.19 PFH37272.1 - 1.5e-08 35.2 0.0 3e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 OTU-like cysteine protease TFIID-31kDa PF02291.15 PFH37272.1 - 0.18 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit UPF0242 PF06785.11 PFH37273.1 - 0.0035 17.5 9.2 0.0067 16.6 9.2 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 PFH37273.1 - 1.4 8.7 8.7 30 4.3 8.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) NUC153 PF08159.12 PFH37274.1 - 4.9e-11 42.2 0.9 4.9e-11 42.2 0.9 3.0 3 0 0 3 3 3 2 NUC153 domain UPF0240 PF06784.11 PFH37274.1 - 4.1 7.4 10.0 2.6 8.1 5.7 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) Exo_endo_phos PF03372.23 PFH37276.1 - 2e-09 37.3 0.1 1.1e-08 34.9 0.1 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF5134 PF17197.4 PFH37278.1 - 0.016 15.1 0.6 0.016 15.1 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) Adeno_E1B_55K PF01696.17 PFH37278.1 - 0.086 11.5 0.3 0.13 10.9 0.3 1.1 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen ARGLU PF15346.6 PFH37280.1 - 7.3e-28 97.4 46.6 1e-27 96.9 46.6 1.2 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 Bin3 PF06859.12 PFH37282.1 - 1.7e-26 93.0 0.0 3e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 PFH37282.1 - 4.2e-09 36.4 0.1 9e-08 32.0 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PFH37282.1 - 5.7e-07 29.5 0.0 4.8e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH37282.1 - 1.1e-06 29.2 0.2 6.4e-05 23.6 0.1 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH37282.1 - 2.9e-06 27.9 0.1 0.0052 17.5 0.1 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 PFH37282.1 - 3e-06 27.8 0.1 0.0015 19.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 PFH37282.1 - 0.00012 21.6 0.1 0.00019 21.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 PFH37282.1 - 0.008 16.2 0.7 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PFH37282.1 - 0.026 14.1 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 PFH37282.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 PFH37282.1 - 0.15 11.0 0.0 0.35 9.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 PFH37282.1 - 0.23 11.4 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_77 PF02446.17 PFH37284.1 - 1.6e-132 442.7 0.1 2.9e-132 441.8 0.1 1.3 1 1 0 1 1 1 1 4-alpha-glucanotransferase DUF4331 PF14224.6 PFH37284.1 - 0.044 13.0 0.0 0.065 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4331) DUF2157 PF09925.9 PFH37284.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) RP-C_C PF11800.8 PFH37284.1 - 0.23 11.6 0.0 0.43 10.6 0.0 1.4 1 1 0 1 1 1 0 Replication protein C C-terminal region FAST_1 PF06743.15 PFH37286.1 - 0.06 13.3 0.0 3.8 7.5 0.0 3.5 2 1 0 3 3 3 0 FAST kinase-like protein, subdomain 1 AKAP7_NLS PF10469.9 PFH37287.1 - 7.9e-54 182.7 0.0 1.1e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 PFH37287.1 - 3.2e-07 30.1 0.0 9.1e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 KH domain PurS PF02700.14 PFH37287.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase UPF0113_N PF17833.1 PFH37290.1 - 4e-29 101.0 0.5 6.8e-29 100.3 0.5 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 PFH37290.1 - 2.5e-18 66.1 0.0 6.1e-18 64.9 0.0 1.7 2 0 0 2 2 2 1 UPF0113 PUA domain LRR_4 PF12799.7 PFH37291.1 - 5.9e-16 58.3 25.7 7e-06 26.3 0.8 5.8 3 1 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH37291.1 - 2.2e-13 49.7 17.1 3.8e-08 33.0 2.1 4.2 4 0 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 PFH37291.1 - 9.9e-12 44.7 0.8 9.5e-06 25.2 0.0 3.0 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 PFH37291.1 - 0.00019 21.2 5.2 4.5 7.6 0.2 5.4 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 PFH37291.1 - 0.0034 17.7 19.1 2.9 8.8 0.8 7.3 7 2 0 7 7 7 1 Leucine Rich Repeat DRY_EERY PF09750.9 PFH37292.1 - 4.8e-14 52.8 0.5 4.8e-14 52.8 0.5 2.8 2 0 0 2 2 2 1 Alternative splicing regulator Surp PF01805.20 PFH37292.1 - 2.3e-07 30.7 0.2 5.7e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 Surp module SHS2_Rpb7-N PF03876.17 PFH37293.1 - 2.4e-14 53.5 0.1 4.5e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 PFH37293.1 - 7.9e-08 32.5 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain DUF4471 PF14740.6 PFH37294.1 - 3.4e-50 171.0 5.5 7.1e-47 160.1 3.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4471) DUF4470 PF14737.6 PFH37294.1 - 5.6e-18 64.9 0.1 9.7e-18 64.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Mur_ligase_M PF08245.12 PFH37296.1 - 6.3e-10 39.4 0.0 1.3e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Histone_HNS PF00816.21 PFH37296.1 - 0.1 13.4 0.3 0.33 11.8 0.3 1.9 1 0 0 1 1 1 0 H-NS histone family Asparaginase_C PF17763.1 PFH37296.1 - 0.11 12.7 0.0 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain Hep_59 PF07052.11 PFH37296.1 - 0.7 10.7 3.3 2.8 8.7 1.6 2.2 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 PUB PF09409.10 PFH37299.1 - 2.2e-14 53.1 0.0 4.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 PUB domain Rhodanese PF00581.20 PFH37299.1 - 0.00044 20.8 0.0 1.5 9.4 0.0 2.7 2 0 0 2 2 2 2 Rhodanese-like domain Utp11 PF03998.13 PFH37302.1 - 2.3e-20 73.6 23.1 2.9e-14 53.6 9.1 2.8 2 1 0 3 3 3 2 Utp11 protein tRNA_int_endo PF01974.17 PFH37302.1 - 2.9e-15 56.1 0.0 6.6e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Porphobil_deam PF01379.20 PFH37303.1 - 1.2e-53 181.6 0.0 1.9e-51 174.5 0.0 3.3 1 1 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 PFH37303.1 - 1e-11 45.1 0.2 3.2e-05 24.2 0.2 2.5 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain TPR_19 PF14559.6 PFH37305.1 - 0.057 13.9 1.2 0.23 12.0 1.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 PFH37305.1 - 2 8.4 3.8 12 5.9 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PFH37305.1 - 2.9 8.2 8.9 2.1 8.7 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 PFH37305.1 - 3 8.9 7.7 0.5 11.3 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat NPL4 PF05021.15 PFH37306.1 - 3.3e-29 102.2 0.0 4.3e-27 95.3 0.0 2.8 1 1 0 1 1 1 1 NPL4 family UN_NPL4 PF11543.8 PFH37306.1 - 1.9e-11 44.3 0.0 8.1e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 zf-NPL4 PF05020.15 PFH37306.1 - 2e-06 28.0 0.0 5.2e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region Hydrolase_4 PF12146.8 PFH37307.1 - 1.2e-14 54.2 0.0 1.2e-13 50.9 0.0 2.0 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PFH37307.1 - 2.7e-06 27.2 0.2 6.2e-06 26.0 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 PFH37307.1 - 0.0055 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Rrp15p PF07890.12 PFH37307.1 - 0.78 10.1 3.8 0.27 11.6 0.7 1.7 2 0 0 2 2 2 0 Rrp15p DUF3602 PF12223.8 PFH37308.1 - 1 10.0 6.3 4.6 7.9 1.6 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) Tam41_Mmp37 PF09139.11 PFH37309.1 - 0.023 14.1 2.1 0.21 11.0 0.2 2.2 2 0 0 2 2 2 0 Phosphatidate cytidylyltransferase, mitochondrial P5CR_dimer PF14748.6 PFH37311.1 - 3.6e-28 97.8 0.9 7.4e-28 96.8 0.9 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 PFH37311.1 - 2.6e-09 37.5 0.1 5.6e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent tRNA-synt_2b PF00587.25 PFH37312.1 - 6.3e-22 78.4 0.0 2.6e-21 76.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Zf_RING PF16744.5 PFH37313.1 - 0.83 9.8 6.0 0.13 12.3 0.2 2.7 3 0 0 3 3 3 0 KIAA1045 RING finger PHD PF00628.29 PFH37313.1 - 1.2 9.0 15.1 0.027 14.4 4.3 3.0 3 0 0 3 3 3 0 PHD-finger Wound_ind PF08186.11 PFH37313.1 - 9.1 6.8 6.7 15 6.1 1.2 4.0 2 0 0 2 2 2 0 Wound-inducible basic protein family EF-hand_6 PF13405.6 PFH37314.1 - 9.9e-06 25.1 0.0 0.0022 17.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PFH37314.1 - 2.6e-05 24.6 1.4 0.0058 17.1 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PFH37314.1 - 0.0091 15.5 0.0 0.064 12.8 0.0 2.4 2 0 0 2 2 2 1 EF hand Pkinase PF00069.25 PFH37315.1 - 3.8e-19 69.1 0.0 2.7e-18 66.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PFH37315.1 - 2.9e-12 46.5 0.0 5.8e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH37315.1 - 0.00044 19.6 0.0 0.002 17.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 PFH37315.1 - 0.0024 17.2 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH37315.1 - 0.0031 17.5 0.4 0.01 15.8 0.4 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 PFH37315.1 - 0.025 14.2 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 PFH37315.1 - 0.068 11.9 0.1 0.099 11.4 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 PFH37315.1 - 0.21 10.5 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Thioredoxin_6 PF13848.6 PFH37316.1 - 9.3e-25 87.6 0.0 6.5e-24 84.9 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 PFH37316.1 - 1.2e-17 63.8 0.0 5.1e-10 39.3 0.0 3.2 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_7 PF13899.6 PFH37316.1 - 4.6e-07 29.9 0.3 0.0075 16.4 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 PFH37316.1 - 5e-06 26.7 0.0 0.09 13.1 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 PFH37316.1 - 8.5e-05 23.0 0.0 0.25 11.8 0.0 3.7 3 0 0 3 3 3 1 Thioredoxin-like domain Filamin PF00630.19 PFH37318.1 - 3.1e-12 47.2 0.0 6.5e-10 39.8 0.0 3.4 3 0 0 3 3 3 1 Filamin/ABP280 repeat CH PF00307.31 PFH37319.1 - 2.9e-06 27.4 0.0 4.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 PFH37319.1 - 0.0013 18.8 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 PFH37319.1 - 0.0085 15.9 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain EB1 PF03271.17 PFH37319.1 - 0.034 14.4 0.2 0.084 13.1 0.2 1.7 1 0 0 1 1 1 0 EB1-like C-terminal motif DUF676 PF05057.14 PFH37320.1 - 6.4e-27 94.5 0.0 8.6e-25 87.5 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Palm_thioest PF02089.15 PFH37320.1 - 0.041 13.7 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LRR_9 PF14580.6 PFH37321.1 - 2.7e-14 53.1 0.0 6.8e-14 51.7 0.0 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PFH37321.1 - 6e-07 29.1 0.7 8.1e-05 22.3 0.3 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PFH37321.1 - 1.9e-06 28.1 1.0 0.0015 18.9 0.1 3.0 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PFH37321.1 - 0.071 13.2 0.0 2.5 8.4 0.0 2.9 3 0 0 3 3 3 0 Leucine Rich repeat Hid1 PF12722.7 PFH37321.1 - 0.078 11.1 0.2 0.098 10.8 0.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SDA1 PF05285.12 PFH37321.1 - 0.54 9.6 28.5 0.83 9.0 28.5 1.2 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 PFH37321.1 - 2.3 7.9 16.3 4.6 6.9 16.3 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Mpp10 PF04006.12 PFH37321.1 - 3.6 5.9 35.1 5.1 5.4 35.1 1.1 1 0 0 1 1 1 0 Mpp10 protein Lip_prot_lig_C PF10437.9 PFH37322.1 - 1.5e-17 63.4 0.0 1.5e-16 60.1 0.0 2.2 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.19 PFH37322.1 - 0.0006 19.7 0.0 0.012 15.6 0.0 2.3 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family FAST_1 PF06743.15 PFH37323.1 - 2.5e-06 27.3 0.2 0.034 14.1 0.1 3.8 3 0 0 3 3 3 2 FAST kinase-like protein, subdomain 1 RAP PF08373.10 PFH37323.1 - 0.0068 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 RAP domain tRNA_U5-meth_tr PF05958.11 PFH37324.1 - 3.4e-22 78.9 0.1 1.2e-21 77.1 0.1 1.7 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 PFH37324.1 - 5.1e-05 23.9 0.0 0.00014 22.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PFH37324.1 - 0.0005 19.9 0.0 0.00085 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PFH37324.1 - 0.0037 17.9 0.0 0.0082 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF4528 PF15031.6 PFH37324.1 - 0.017 15.1 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) Sugar_tr PF00083.24 PFH37325.1 - 4.4e-85 286.2 23.4 5.1e-85 286.0 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PFH37325.1 - 1.6e-35 122.7 42.2 5.6e-30 104.5 22.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 PFH37325.1 - 3.5e-08 32.3 2.3 3.5e-08 32.3 2.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) YukC PF10140.9 PFH37325.1 - 0.13 11.1 0.7 0.42 9.4 0.1 1.8 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC VirB8 PF04335.13 PFH37325.1 - 1.2 8.9 3.9 0.49 10.2 0.8 2.0 2 1 0 2 2 2 0 VirB8 protein Peptidase_M14 PF00246.24 PFH37326.1 - 2e-33 116.5 0.0 1.1e-32 114.0 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase zf-B_box PF00643.24 PFH37327.1 - 2.6e-13 49.9 13.1 4.2e-07 30.0 3.0 2.3 2 0 0 2 2 2 2 B-box zinc finger zf-UBR PF02207.20 PFH37327.1 - 0.0076 16.4 0.6 0.0076 16.4 0.6 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) SDA1 PF05285.12 PFH37327.1 - 0.016 14.7 22.8 0.12 11.8 7.5 2.5 2 0 0 2 2 2 0 SDA1 CEBP_ZZ PF16366.5 PFH37327.1 - 0.03 14.6 5.7 0.09 13.0 5.7 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DHC_N1 PF08385.12 PFH37327.1 - 0.087 11.5 0.2 0.14 10.8 0.2 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 DUF587 PF04532.12 PFH37327.1 - 0.11 11.8 0.1 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF587) Baculo_PEP_C PF04513.12 PFH37327.1 - 0.12 12.4 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 PFH37327.1 - 0.95 8.7 2.0 1.8 7.8 2.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TRAP_alpha PF03896.16 PFH37327.1 - 9.5 5.3 6.0 27 3.8 6.0 1.7 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit adh_short PF00106.25 PFH37328.1 - 1.9e-39 135.2 0.1 2.5e-39 134.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PFH37328.1 - 2.7e-24 86.0 0.1 3.6e-24 85.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PFH37328.1 - 5.8e-05 23.1 0.1 9.2e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PFH37328.1 - 0.0042 16.5 0.0 0.015 14.7 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 PFH37328.1 - 0.0064 16.1 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PFH37328.1 - 0.0074 15.8 0.1 0.024 14.1 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PFH37328.1 - 0.018 14.9 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Thioesterase PF00975.20 PFH37330.1 - 3.7e-15 56.7 0.0 9.6e-15 55.3 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 PFH37330.1 - 9.5e-10 39.4 0.1 1.2e-09 39.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DnaJ PF00226.31 PFH37331.1 - 9.9e-12 44.8 0.1 3.2e-11 43.2 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain ERM PF00769.19 PFH37331.1 - 1.1e-07 31.9 6.7 1.1e-07 31.9 6.7 1.8 2 1 0 2 2 2 1 Ezrin/radixin/moesin family DUF4570 PF15134.6 PFH37331.1 - 0.036 14.1 5.4 0.11 12.5 5.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF4746 PF15928.5 PFH37331.1 - 0.35 10.3 3.5 0.71 9.2 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4407 PF14362.6 PFH37331.1 - 0.85 8.9 21.2 0.33 10.3 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Nop14 PF04147.12 PFH37332.1 - 8.3 4.5 16.2 17 3.4 16.2 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 PFH37332.1 - 9.3 4.4 22.8 2.5 6.3 0.3 3.4 3 1 0 3 3 3 0 CDC45-like protein Amidase PF01425.21 PFH37334.1 - 0.014 14.4 0.0 3.2 6.6 0.0 3.1 3 0 0 3 3 3 0 Amidase Luteo_Vpg PF01659.16 PFH37335.1 - 0.13 12.6 2.0 0.69 10.3 2.0 2.4 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein DUF3273 PF11677.8 PFH37336.1 - 4e-105 350.9 8.8 4.7e-105 350.7 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) PTCRA PF15028.6 PFH37337.1 - 0.0055 16.4 0.4 0.25 11.0 0.0 2.8 1 1 1 2 2 2 1 Pre-T-cell antigen receptor GET2 PF08690.10 PFH37337.1 - 0.13 11.9 0.7 0.26 10.9 0.7 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 SAG PF04092.13 PFH37338.1 - 3.1e-25 89.5 0.9 5e-06 27.3 0.4 4.5 4 1 0 4 4 4 4 SRS domain WRKY PF03106.15 PFH37338.1 - 0.022 15.0 6.3 9.5 6.5 0.0 4.5 5 0 0 5 5 5 0 WRKY DNA -binding domain Poxvirus_B22R PF04395.12 PFH37338.1 - 0.1 12.1 0.0 9 5.8 0.0 3.0 3 0 0 3 3 3 0 Poxvirus B22R protein MACPF PF01823.19 PFH37339.1 - 5.7e-46 157.3 0.0 9.2e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain Shadoo PF14999.6 PFH37340.1 - 9.4 6.3 20.3 57 3.8 20.3 1.8 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective Fib_alpha PF08702.10 PFH37342.1 - 0.74 10.0 7.2 1.5 9.0 7.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Gar1 PF04410.14 PFH37343.1 - 1.1e-37 129.2 0.0 1.3e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Kelch_1 PF01344.25 PFH37344.1 - 1.3e-37 127.1 5.3 1.8e-12 46.6 0.0 5.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 PFH37344.1 - 1.2e-19 69.9 0.0 9e-05 22.6 0.0 5.5 3 1 2 5 5 5 4 Kelch motif Kelch_4 PF13418.6 PFH37344.1 - 1e-16 60.6 2.8 0.00037 20.5 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 PFH37344.1 - 1.3e-15 57.3 1.9 0.00013 22.1 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 PFH37344.1 - 3.4e-11 42.7 1.8 0.00013 21.8 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 PFH37344.1 - 2.1e-05 24.4 3.6 0.39 10.8 0.0 4.5 4 0 0 4 4 4 2 Kelch motif ANAPC4_WD40 PF12894.7 PFH37345.1 - 0.16 12.3 0.2 3.5 8.0 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT PF02985.22 PFH37346.1 - 0.013 15.7 0.1 0.15 12.4 0.1 3.0 1 0 0 1 1 1 0 HEAT repeat Steroid_dh PF02544.16 PFH37348.1 - 3.1e-08 33.7 0.9 5.4e-07 29.7 0.8 2.2 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Pkinase PF00069.25 PFH37350.1 - 2.7e-55 187.6 0.0 9e-34 117.0 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH37350.1 - 3e-24 85.7 0.3 1.2e-17 64.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PFH37350.1 - 2.2e-08 34.3 0.1 0.00015 21.8 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PFH37350.1 - 7e-06 25.6 0.6 0.043 13.1 0.1 3.1 2 1 1 3 3 3 2 Kinase-like YukC PF10140.9 PFH37350.1 - 0.023 13.5 0.1 0.035 12.9 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pox_ser-thr_kin PF05445.11 PFH37350.1 - 0.09 11.7 0.2 0.13 11.2 0.2 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cons_hypoth95 PF03602.15 PFH37351.1 - 9.8e-31 106.8 0.0 5.9e-23 81.4 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 PFH37351.1 - 0.0025 17.4 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 PFH37351.1 - 0.0083 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PFH37351.1 - 0.13 13.0 0.0 0.28 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Proteasome PF00227.26 PFH37352.1 - 8.2e-19 67.8 0.3 2.4e-18 66.3 0.3 1.7 1 1 0 1 1 1 1 Proteasome subunit LytR_C PF13399.6 PFH37353.1 - 0.3 12.1 1.6 0.43 11.6 0.5 1.8 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator SPICE PF15678.5 PFH37354.1 - 0.095 12.0 5.6 0.027 13.8 0.6 2.2 2 0 0 2 2 2 0 Centriole duplication and mitotic chromosome congression Dpy-30 PF05186.13 PFH37355.1 - 4.2e-12 45.6 0.0 9.1e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 Dpy-30 motif Wyosine_form PF08608.12 PFH37357.1 - 1.5e-24 86.1 0.3 6.1e-24 84.1 0.1 2.1 2 0 0 2 2 2 1 Wyosine base formation Radical_SAM PF04055.21 PFH37357.1 - 2.3e-20 73.6 0.0 4.7e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 PFH37357.1 - 3.6e-09 37.0 0.0 2.6e-07 30.9 0.0 2.6 2 0 0 2 2 2 1 Flavodoxin DUF1682 PF07946.14 PFH37357.1 - 0.18 11.0 0.9 0.37 10.0 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Macoilin PF09726.9 PFH37357.1 - 0.29 9.6 1.4 0.6 8.6 1.4 1.4 1 0 0 1 1 1 0 Macoilin family AF-4 PF05110.13 PFH37357.1 - 3.7 5.5 19.9 8 4.4 19.9 1.5 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4604 PF15377.6 PFH37358.1 - 0.0056 17.1 9.5 0.0056 17.1 9.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Pex24p PF06398.11 PFH37358.1 - 0.031 13.3 0.4 0.036 13.1 0.4 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin VKG_Carbox PF05090.14 PFH37358.1 - 0.28 10.0 0.7 0.33 9.8 0.7 1.0 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase OAD_gamma PF04277.13 PFH37358.1 - 0.5 11.0 8.8 0.71 10.5 8.8 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AP3D1 PF06375.11 PFH37358.1 - 0.94 9.7 18.4 1.2 9.4 18.4 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Rsc14 PF08586.10 PFH37358.1 - 1.3 9.8 6.6 1.8 9.5 6.6 1.2 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit Tmemb_161AB PF10268.9 PFH37358.1 - 1.7 7.2 2.9 1.6 7.3 2.9 1.0 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB DUF3464 PF11947.8 PFH37358.1 - 3.4 7.4 7.9 3.7 7.3 7.9 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Peptidase_S49_N PF08496.10 PFH37358.1 - 8.4 6.4 14.7 10 6.2 14.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RRM_1 PF00076.22 PFH37360.1 - 2.2e-25 88.3 0.1 1.8e-14 53.3 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH37360.1 - 0.00033 20.7 0.0 0.31 11.2 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif Limkain-b1 PF11608.8 PFH37360.1 - 0.00038 20.5 0.2 4.5 7.4 0.0 3.4 3 0 0 3 3 3 1 Limkain b1 RRM_3 PF08777.11 PFH37360.1 - 0.0049 16.9 0.0 0.15 12.1 0.0 2.6 2 1 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 PFH37360.1 - 0.0055 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 PFH37360.1 - 0.006 16.2 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 PFH37360.1 - 0.05 13.4 0.1 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain PHM7_cyt PF14703.6 PFH37360.1 - 0.084 13.1 1.2 6.9 6.9 0.0 3.5 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Rad51 PF08423.11 PFH37361.1 - 1.9e-120 400.9 0.0 2.7e-120 400.4 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 PFH37361.1 - 1.1e-10 41.5 0.0 1.5e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 PFH37361.1 - 1.7e-07 31.0 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 PFH37361.1 - 4.9e-05 22.8 0.0 0.0001 21.7 0.0 1.5 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 PFH37361.1 - 0.005 17.4 0.0 0.015 15.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.6 PFH37361.1 - 0.0077 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cpn60_TCP1 PF00118.24 PFH37363.1 - 2.1e-153 511.5 12.2 2.3e-153 511.4 12.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Kinase-like PF14531.6 PFH37364.1 - 1.8e-53 181.7 0.0 5.8e-53 180.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.25 PFH37364.1 - 8.8e-26 90.8 0.0 1.3e-20 73.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH37364.1 - 4.9e-11 42.4 0.0 1.9e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 PFH37364.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH37364.1 - 0.016 15.1 2.4 0.05 13.5 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family His_Phos_1 PF00300.22 PFH37365.1 - 2.6e-44 151.2 0.0 3.8e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_S17 PF00366.20 PFH37368.1 - 1.2e-14 54.1 0.2 1.8e-14 53.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 RIIa PF02197.17 PFH37369.1 - 0.00084 19.0 0.1 0.0021 17.7 0.1 1.8 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit ArfGap PF01412.18 PFH37370.1 - 6.3e-30 103.7 0.1 1.3e-29 102.7 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf AAA PF00004.29 PFH37371.1 - 5.7e-94 311.5 0.0 1.4e-46 158.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PFH37371.1 - 6e-24 83.6 13.2 8.8e-14 51.0 0.9 3.0 3 1 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 PFH37371.1 - 7.6e-23 80.5 0.4 1.9e-22 79.2 0.4 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 PFH37371.1 - 1.4e-13 50.9 0.0 8.9e-06 25.5 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PFH37371.1 - 2.5e-12 47.5 0.6 0.00059 20.3 0.0 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 PFH37371.1 - 5.7e-11 42.8 0.0 1.8e-06 28.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PFH37371.1 - 6.6e-11 42.4 0.1 2.7e-05 24.2 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 PFH37371.1 - 8.4e-11 42.2 0.0 4.6e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 PFH37371.1 - 9.8e-11 41.3 0.0 2.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 PFH37371.1 - 4.5e-09 36.7 0.3 0.019 15.3 0.1 4.1 2 2 1 3 3 2 2 AAA domain TIP49 PF06068.13 PFH37371.1 - 1.3e-08 34.4 0.0 0.0011 18.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 PFH37371.1 - 1.3e-07 31.7 0.0 0.0016 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 PFH37371.1 - 2.8e-07 31.1 0.0 0.028 15.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 PFH37371.1 - 3.8e-07 30.4 0.0 0.016 15.6 0.0 3.1 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 PFH37371.1 - 5.5e-07 29.2 0.3 0.037 13.4 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 PFH37371.1 - 1.4e-06 28.0 0.7 0.7 9.4 0.0 3.8 3 1 0 4 4 3 2 AAA domain Vps4_C PF09336.10 PFH37371.1 - 3.8e-06 26.8 0.1 0.00036 20.5 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 PFH37371.1 - 1.3e-05 25.0 0.0 0.18 11.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 PFH37371.1 - 2.9e-05 24.1 0.1 0.55 10.1 0.0 3.2 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_7 PF12775.7 PFH37371.1 - 4.2e-05 23.1 0.0 0.35 10.3 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_17 PF13207.6 PFH37371.1 - 4.3e-05 24.0 0.0 0.17 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 PFH37371.1 - 5e-05 23.6 0.0 0.32 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 PFH37371.1 - 5e-05 22.7 0.3 2.5 7.4 0.0 3.4 2 1 0 3 3 3 2 KaiC ABC_tran PF00005.27 PFH37371.1 - 5.4e-05 23.7 0.0 0.32 11.5 0.0 2.9 2 1 0 2 2 2 2 ABC transporter Viral_helicase1 PF01443.18 PFH37371.1 - 6.1e-05 22.9 0.0 0.0087 15.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 PFH37371.1 - 8.1e-05 22.6 0.1 0.52 10.2 0.0 3.3 2 1 1 3 3 3 2 NACHT domain AAA_24 PF13479.6 PFH37371.1 - 0.0001 22.1 0.0 0.12 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 PFH37371.1 - 0.0001 22.3 0.0 0.9 9.5 0.0 3.1 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 PFH37371.1 - 0.00021 20.5 0.0 0.52 9.4 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 PFH37371.1 - 0.00021 20.5 0.0 0.85 8.7 0.0 2.8 3 0 0 3 3 2 2 NB-ARC domain Sigma54_activat PF00158.26 PFH37371.1 - 0.00048 19.9 0.0 1.4 8.6 0.0 3.4 2 2 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 PFH37371.1 - 0.00049 19.4 0.0 0.79 9.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Bac_DnaA PF00308.18 PFH37371.1 - 0.00078 19.3 0.0 0.38 10.6 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein Sigma54_activ_2 PF14532.6 PFH37371.1 - 0.00082 19.5 0.0 0.52 10.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 PFH37371.1 - 0.0016 17.7 0.0 0.66 9.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 PFH37371.1 - 0.0023 17.8 0.0 2.5 7.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 PFH37371.1 - 0.0024 17.3 0.2 1.8 8.0 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Rad17 PF03215.15 PFH37371.1 - 0.0031 17.4 0.0 1.8 8.4 0.0 2.7 2 1 0 3 3 2 1 Rad17 P-loop domain ResIII PF04851.15 PFH37371.1 - 0.0049 16.9 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cytidylate_kin2 PF13189.6 PFH37371.1 - 0.0058 16.8 0.1 2 8.5 0.0 2.6 3 0 0 3 3 2 1 Cytidylate kinase-like family DUF2075 PF09848.9 PFH37371.1 - 0.0064 15.8 0.0 0.66 9.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 PFH37371.1 - 0.0075 16.2 0.7 6.5 6.6 0.0 3.6 3 0 0 3 3 3 0 NTPase AAA_19 PF13245.6 PFH37371.1 - 0.01 16.2 0.4 5.2 7.4 0.1 3.1 3 1 1 4 4 2 0 AAA domain KAP_NTPase PF07693.14 PFH37371.1 - 0.018 14.3 0.1 3.1 6.9 0.0 3.3 2 2 2 4 4 4 0 KAP family P-loop domain AAA_30 PF13604.6 PFH37371.1 - 0.026 14.3 0.2 6.7 6.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 PFH37371.1 - 0.045 13.5 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PFH37371.1 - 0.057 13.2 0.0 6 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain SKI PF01202.22 PFH37371.1 - 0.069 13.3 0.2 23 5.1 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase UFD1 PF03152.14 PFH37371.1 - 0.083 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin PF02224.18 PFH37371.1 - 0.087 12.5 0.1 8.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Hydin_ADK PF17213.3 PFH37371.1 - 2 8.7 4.0 56 3.9 0.0 3.8 5 0 0 5 5 3 0 Hydin Adenylate kinase-like domain DNA_pol_A_exo1 PF01612.20 PFH37372.1 - 1.9e-22 79.8 0.0 2.8e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease SAG PF04092.13 PFH37374.1 - 1.3e-12 48.6 4.9 2.2e-06 28.5 0.2 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37375.1 - 9.7e-17 62.0 13.6 1.6e-09 38.6 5.1 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37376.1 - 1.2e-14 55.2 10.3 2e-07 31.8 0.2 2.2 2 0 0 2 2 2 2 SRS domain YppG PF14179.6 PFH37376.1 - 0.0085 16.8 0.1 0.019 15.7 0.1 1.5 1 0 0 1 1 1 1 YppG-like protein DUF2631 PF10939.8 PFH37376.1 - 0.2 11.5 0.7 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) DUF2180 PF09947.9 PFH37376.1 - 0.52 10.3 3.9 0.17 11.9 0.5 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) SAG PF04092.13 PFH37377.1 - 2.2e-13 51.1 2.8 2e-05 25.4 1.2 2.5 2 1 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37378.1 - 5.3e-16 59.6 10.1 6.1e-09 36.7 1.0 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37379.1 - 2.7e-15 57.3 6.1 3e-07 31.3 0.3 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37380.1 - 1.8e-10 41.7 7.1 8.5e-05 23.3 0.4 2.4 2 0 0 2 2 2 2 SRS domain Adap_comp_sub PF00928.21 PFH37380.1 - 0.052 12.9 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 Adaptor complexes medium subunit family SAG PF04092.13 PFH37381.1 - 1.8e-14 54.6 11.0 9.1e-08 33.0 1.2 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37382.1 - 1.3e-17 64.8 4.0 3.8e-08 34.2 0.1 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37383.1 - 2.1e-10 41.5 4.1 0.00011 23.0 1.0 2.2 2 0 0 2 2 2 2 SRS domain Defb50 PF17546.2 PFH37383.1 - 0.0016 18.3 0.0 0.067 13.1 0.0 2.5 2 0 0 2 2 2 1 Beta defensin 50 Radical_SAM PF04055.21 PFH37384.1 - 2.3e-16 60.6 0.0 8.1e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 PFH37384.1 - 4.8e-16 58.6 0.6 3.1e-15 56.0 0.1 2.5 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Hen1_Lam_C PF18441.1 PFH37384.1 - 0.027 14.3 0.1 0.064 13.1 0.0 1.6 2 0 0 2 2 2 0 Hen1 La-motif C-terminal domain zf-C3HC4_2 PF13923.6 PFH37385.1 - 0.00035 20.3 9.8 0.00073 19.3 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PFH37385.1 - 0.00037 20.3 10.6 0.00063 19.6 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PFH37385.1 - 0.00091 19.3 10.0 0.0016 18.5 10.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PFH37385.1 - 0.0014 18.6 4.6 0.0017 18.3 3.4 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PFH37385.1 - 0.016 15.0 10.4 0.028 14.3 10.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH37385.1 - 0.021 14.8 11.8 0.035 14.1 11.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 PFH37385.1 - 0.12 12.7 11.0 0.27 11.6 11.0 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.6 PFH37385.1 - 0.13 12.1 5.8 0.3 11.0 5.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 PFH37385.1 - 1.8 8.5 8.9 3.8 7.5 8.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Solute_trans_a PF03619.16 PFH37386.1 - 3.5e-51 174.3 18.7 1.6e-49 168.8 4.9 2.9 2 1 0 3 3 3 2 Organic solute transporter Ostalpha P34-Arc PF04045.14 PFH37387.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Arp2/3 complex, 34 kD subunit p34-Arc PIEZO PF15917.5 PFH37388.1 - 0.071 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Piezo Mpv17_PMP22 PF04117.12 PFH37389.1 - 9.1e-13 48.2 1.7 2e-12 47.1 1.7 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family SKA2 PF16740.5 PFH37390.1 - 0.017 14.9 0.1 0.036 13.8 0.1 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 HemY_N PF07219.13 PFH37391.1 - 0.031 14.5 0.1 0.074 13.3 0.1 1.7 1 0 0 1 1 1 0 HemY protein N-terminus FeoB_C PF07664.12 PFH37391.1 - 2.1 8.1 5.6 1.2 8.9 3.3 1.8 2 1 0 2 2 2 0 Ferrous iron transport protein B C terminus MoaE PF02391.17 PFH37393.1 - 7.5e-26 90.6 1.0 2.9e-20 72.6 0.3 2.2 2 0 0 2 2 2 2 MoaE protein ABC_tran PF00005.27 PFH37394.1 - 3.3e-32 111.9 0.0 5.5e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 PFH37394.1 - 1.9e-25 90.0 4.3 2.8e-25 89.5 4.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 PFH37394.1 - 0.00013 21.5 0.0 0.0014 18.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PFH37394.1 - 0.00054 20.4 0.4 0.0082 16.5 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain PT PF04886.12 PFH37394.1 - 0.0045 16.5 27.3 4.9 6.8 27.3 2.8 1 1 0 1 1 1 1 PT repeat AAA_29 PF13555.6 PFH37394.1 - 0.017 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 PFH37394.1 - 0.032 14.3 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_33 PF13671.6 PFH37394.1 - 0.034 14.3 0.1 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PFH37394.1 - 0.046 14.3 0.0 0.099 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PFH37394.1 - 0.12 12.7 0.2 0.39 11.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain Adaptin_N PF01602.20 PFH37395.1 - 7.7e-92 308.5 2.9 9.7e-92 308.2 2.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 PFH37395.1 - 4.1e-26 91.9 0.0 1.1e-25 90.5 0.0 1.7 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 PFH37395.1 - 5.6e-25 87.7 0.1 1.4e-24 86.5 0.0 1.8 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform Cnd1 PF12717.7 PFH37395.1 - 1.2e-11 44.9 6.3 0.00022 21.3 0.5 3.8 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PFH37395.1 - 2.2e-10 40.8 14.5 0.00055 20.3 0.3 5.8 4 2 0 5 5 5 3 HEAT repeats HEAT PF02985.22 PFH37395.1 - 0.002 18.2 15.7 0.93 9.9 0.0 7.9 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.6 PFH37395.1 - 9.5 6.9 19.1 0.23 12.0 0.3 6.1 6 1 0 6 6 6 0 HEAT-like repeat BK_channel_a PF03493.18 PFH37396.1 - 2e-12 47.1 0.0 4.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 PFH37396.1 - 2.2e-10 40.3 1.7 2.2e-10 40.3 1.7 1.9 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 PFH37396.1 - 0.00022 20.5 9.7 0.00038 19.8 9.7 1.2 1 0 0 1 1 1 1 Ion transport protein Mito_carr PF00153.27 PFH37397.1 - 2.3e-56 187.7 5.5 5.4e-18 64.7 0.3 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PFH37397.1 - 0.037 13.2 3.3 2.4 7.2 0.9 2.9 2 1 1 3 3 3 0 Gammaproteobacterial serine protease Caprin-1_dimer PF18293.1 PFH37398.1 - 0.034 14.6 0.1 0.069 13.7 0.1 1.5 1 0 0 1 1 1 0 Caprin-1 dimerization domain tRNA-synt_1b PF00579.25 PFH37399.1 - 7.9e-36 123.9 0.0 2.5e-26 92.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) S4 PF01479.25 PFH37399.1 - 0.00018 21.2 0.8 0.00079 19.1 0.1 2.3 2 0 0 2 2 2 1 S4 domain PUA_3 PF17785.1 PFH37400.1 - 3.2e-12 46.1 0.0 1.1e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 PUA-like domain Methyltrans_SAM PF10672.9 PFH37400.1 - 1.2e-06 27.9 0.0 2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Met_10 PF02475.16 PFH37400.1 - 0.00012 21.8 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 PFH37400.1 - 0.00018 21.2 0.0 0.00049 19.8 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 UPF0051 PF01458.17 PFH37402.1 - 2.1e-42 145.3 0.0 2.8e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Paf67 PF10255.9 PFH37403.1 - 2.9e-142 474.4 12.0 3.5e-142 474.1 12.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPH PF13868.6 PFH37404.1 - 7.2e-08 31.3 74.4 7.2e-08 31.3 74.4 3.6 2 2 1 3 3 3 1 Trichohyalin-plectin-homology domain PFEMP PF03011.15 PFH37404.1 - 0.0024 18.6 10.8 0.0024 18.6 10.8 3.7 2 1 4 6 6 6 1 PFEMP DBL domain Exostosin PF03016.15 PFH37406.1 - 7e-10 38.6 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Exostosin family DUF2981 PF11200.8 PFH37407.1 - 6.2 6.5 5.6 13 5.5 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Ribosomal_S6 PF01250.17 PFH37408.1 - 1.2e-11 44.7 0.0 1.8e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 Alba PF01918.21 PFH37409.1 - 3.1e-05 23.7 0.0 5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Alba Tctex-1 PF03645.13 PFH37410.1 - 1.2e-22 80.1 0.1 1.5e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family GFA PF04828.14 PFH37410.1 - 0.0056 17.0 0.0 0.0078 16.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF3785 PF12653.7 PFH37410.1 - 0.017 15.3 0.1 0.021 14.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) GAS PF13851.6 PFH37411.1 - 5.3e-45 153.2 32.7 5.3e-45 153.2 32.7 3.6 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding TruB_N PF01509.18 PFH37411.1 - 0.13 12.7 6.3 0.073 13.4 2.9 2.4 2 1 0 2 2 2 0 TruB family pseudouridylate synthase (N terminal domain) DUF728 PF05304.12 PFH37411.1 - 4.3 7.2 6.7 2.5 7.9 0.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF728) TPR_16 PF13432.6 PFH37413.1 - 0.0039 17.8 0.0 0.014 16.1 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 PFH37413.1 - 0.017 15.6 0.1 0.069 13.7 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Ad_Cy_reg PF16701.5 PFH37413.1 - 0.044 13.5 0.8 0.1 12.3 0.1 2.0 2 0 0 2 2 2 0 Adenylate cyclase regulatory domain AsnA PF03590.15 PFH37414.1 - 0.029 14.1 0.0 0.036 13.8 0.0 1.1 1 0 0 1 1 1 0 Aspartate-ammonia ligase eIF-1a PF01176.19 PFH37415.1 - 4.9e-10 39.1 0.0 1.6e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 Translation initiation factor 1A / IF-1 CitMHS PF03600.16 PFH37416.1 - 0.015 14.5 0.0 0.073 12.3 0.0 2.0 2 0 0 2 2 2 0 Citrate transporter Phage_holin_3_6 PF07332.11 PFH37416.1 - 2.9 8.0 9.8 2.6 8.1 0.1 3.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 PFH37417.1 - 3.3e-63 213.5 0.0 7.2e-63 212.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain EF-hand_7 PF13499.6 PFH37417.1 - 4e-29 100.9 5.9 7.5e-15 55.1 1.4 3.5 3 0 0 3 3 3 3 EF-hand domain pair Pkinase_Tyr PF07714.17 PFH37417.1 - 4.9e-28 98.1 0.0 5.3e-22 78.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_6 PF13405.6 PFH37417.1 - 9e-27 90.7 8.2 2.7e-05 23.8 0.0 5.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 PFH37417.1 - 1e-26 90.4 12.4 7.1e-08 31.5 0.7 5.5 5 0 0 5 5 5 5 EF hand EF-hand_8 PF13833.6 PFH37417.1 - 7.9e-19 67.3 8.7 1.5e-08 34.3 0.4 4.6 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 PFH37417.1 - 3.2e-15 54.8 10.4 0.00028 20.2 0.1 4.8 4 1 1 5 5 5 4 EF hand EF-hand_4 PF12763.7 PFH37417.1 - 8.5e-06 25.7 1.7 0.029 14.3 0.1 4.0 2 1 2 4 4 4 1 Cytoskeletal-regulatory complex EF hand APH PF01636.23 PFH37417.1 - 1.8e-05 24.8 0.2 4.5e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PFH37417.1 - 0.00072 19.0 0.1 0.0015 17.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PFH37417.1 - 0.0019 17.1 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase SPARC_Ca_bdg PF10591.9 PFH37417.1 - 0.0045 17.3 1.4 1.1 9.6 0.0 3.1 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 PFH37417.1 - 0.012 15.9 0.3 2.9 8.3 0.1 3.4 3 0 0 3 3 3 0 EF-hand domain Choline_kinase PF01633.20 PFH37417.1 - 0.02 14.5 0.1 0.25 10.9 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Dockerin_1 PF00404.18 PFH37417.1 - 0.035 14.3 0.8 24 5.2 0.0 3.9 4 0 0 4 4 4 0 Dockerin type I domain Caleosin PF05042.13 PFH37417.1 - 0.15 12.0 0.4 32 4.4 0.0 3.4 3 1 1 4 4 4 0 Caleosin related protein DUF3349 PF11829.8 PFH37417.1 - 0.35 11.7 1.4 13 6.7 0.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) Ribosomal_L17 PF01196.19 PFH37418.1 - 1.9e-24 86.3 0.0 3e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 RNA_pol_Rpc34 PF05158.12 PFH37419.1 - 1.8e-33 116.4 2.0 7.2e-28 97.9 0.0 2.3 1 1 0 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 PFH37419.1 - 0.029 14.5 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Ribosomal_S27e PF01667.17 PFH37420.1 - 3.4e-26 90.7 8.6 4.2e-26 90.4 8.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 RNA_pol_N PF01194.17 PFH37421.1 - 3.1e-29 101.1 0.8 3.7e-29 100.8 0.8 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 PFH37421.1 - 0.1 12.9 0.5 0.25 11.6 0.5 1.7 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Hexapep PF00132.24 PFH37422.1 - 1.7e-09 37.0 4.4 0.016 15.0 0.0 4.3 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PFH37422.1 - 0.00061 19.5 5.3 0.091 12.5 0.1 4.3 4 1 1 5 5 5 2 Hexapeptide repeat of succinyl-transferase RRM_1 PF00076.22 PFH37423.1 - 9.2e-26 89.5 0.0 1.6e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH37423.1 - 0.012 15.7 0.0 0.027 14.6 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 PFH37423.1 - 0.11 12.5 0.1 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif OmpH PF03938.14 PFH37424.1 - 0.034 14.5 2.5 0.06 13.7 2.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HMG_box_2 PF09011.10 PFH37426.1 - 4.8e-21 75.1 1.6 9.2e-21 74.2 1.6 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 PFH37426.1 - 4.8e-11 42.9 3.0 1.4e-10 41.4 3.0 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box CBFD_NFYB_HMF PF00808.23 PFH37426.1 - 0.00091 19.5 1.3 0.0035 17.6 0.1 2.5 2 2 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2857 PF11198.8 PFH37426.1 - 0.023 14.5 0.6 0.023 14.5 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) SIS_2 PF13580.6 PFH37426.1 - 0.048 13.7 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 SIS domain tRNA-synt_1c PF00749.21 PFH37431.1 - 2.5e-100 335.4 0.0 2.5e-100 335.4 0.0 2.1 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 PFH37431.1 - 1.4e-49 168.3 0.0 2.4e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 PFH37431.1 - 0.065 13.3 0.3 0.18 11.8 0.3 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tfb5 PF06331.12 PFH37432.1 - 1.6e-19 69.6 1.8 1.9e-19 69.4 0.2 1.7 1 1 1 2 2 2 1 Transcription factor TFIIH complex subunit Tfb5 TK PF00265.18 PFH37432.1 - 0.07 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase HCNGP PF07818.13 PFH37433.1 - 9.8e-16 58.2 0.0 1.9e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein Serpin PF00079.20 PFH37434.1 - 7.5e-63 213.1 0.0 9.5e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Mito_fiss_reg PF05308.11 PFH37435.1 - 4.3 7.3 12.4 29 4.6 8.6 2.7 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF2207 PF09972.9 PFH37436.1 - 0.015 14.1 2.8 0.071 11.9 2.5 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 PFH37436.1 - 0.13 12.3 7.2 0.51 10.4 7.2 2.0 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4834 PF16118.5 PFH37436.1 - 0.29 12.1 2.0 1.4 9.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) MyTH4 PF00784.17 PFH37437.1 - 0.6 10.6 2.3 2.3 8.8 0.1 2.7 2 0 0 2 2 2 0 MyTH4 domain REJ PF02010.15 PFH37438.1 - 7.9e-12 44.7 3.6 0.0033 16.3 0.4 4.8 3 2 1 4 4 4 4 REJ domain Med9 PF07544.13 PFH37439.1 - 0.057 13.5 0.1 0.057 13.5 0.1 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 MT-A70 PF05063.14 PFH37441.1 - 1.1e-55 188.2 0.6 1.6e-55 187.7 0.6 1.2 1 0 0 1 1 1 1 MT-A70 zf-RRN7 PF11781.8 PFH37443.1 - 0.023 14.4 6.0 0.014 15.1 3.5 1.9 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Prim_Zn_Ribbon PF08273.12 PFH37443.1 - 0.32 11.3 2.6 1.1 9.7 2.6 1.9 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase TF_Zn_Ribbon PF08271.12 PFH37443.1 - 0.66 9.5 4.3 1.5 8.4 4.3 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding NOC3p PF07540.11 PFH37444.1 - 4e-12 46.4 0.0 1.2e-10 41.7 0.0 2.7 1 1 0 1 1 1 1 Nucleolar complex-associated protein CAP PF00188.26 PFH37448.1 - 3.4e-06 27.9 2.8 4.8e-06 27.4 0.2 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family UDPGP PF01704.18 PFH37452.1 - 1.9e-18 66.3 0.0 2.7e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Kinesin PF00225.23 PFH37453.1 - 6e-103 344.3 0.0 1.2e-102 343.2 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PFH37453.1 - 1.3e-21 77.1 0.2 6.4e-21 74.9 0.2 2.3 1 1 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 PFH37453.1 - 2.8e-05 24.4 0.3 2.8e-05 24.4 0.3 3.1 3 0 0 3 3 3 1 Kinesin protein 1B Kinesin_assoc PF16183.5 PFH37453.1 - 6.4e-05 23.2 1.9 6.4e-05 23.2 1.9 4.1 3 2 1 4 4 4 1 Kinesin-associated FHA PF00498.26 PFH37453.1 - 0.0047 17.3 0.0 0.019 15.3 0.0 2.1 2 0 0 2 2 2 1 FHA domain FapA PF03961.13 PFH37453.1 - 0.73 8.4 19.3 0.69 8.4 2.4 2.5 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF3626 PF12294.8 PFH37454.1 - 2e-11 43.5 0.0 7.8e-08 31.7 0.0 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF3626) Pkinase PF00069.25 PFH37455.1 - 2.2e-76 256.7 0.0 2.5e-76 256.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH37455.1 - 5.3e-32 111.1 0.0 6.5e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PFH37455.1 - 0.0007 18.6 0.0 0.0078 15.2 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PFH37455.1 - 0.0063 15.9 0.0 0.023 14.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PFH37455.1 - 0.017 14.5 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH37455.1 - 0.023 14.6 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 PFH37455.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 RIO1 family SET PF00856.28 PFH37456.1 - 0.00015 22.2 0.1 0.00037 20.9 0.1 1.7 1 1 0 1 1 1 1 SET domain TAP42 PF04177.12 PFH37458.1 - 2.4e-52 178.1 0.1 3.2e-52 177.6 0.1 1.2 1 0 0 1 1 1 1 TAP42-like family Histone PF00125.24 PFH37459.1 - 8.2e-54 181.5 1.8 9.1e-54 181.3 1.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PFH37459.1 - 5.9e-05 23.7 1.1 7.1e-05 23.4 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PFH37459.1 - 9.1e-05 22.8 0.0 0.00014 22.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PFH37459.1 - 0.00058 20.0 0.7 0.00074 19.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 PFH37459.1 - 0.0089 16.1 0.1 0.015 15.3 0.0 1.5 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 PFH37459.1 - 0.02 15.1 0.7 0.029 14.7 0.1 1.5 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Nucleos_tra2_C PF07662.13 PFH37460.1 - 0.1 12.4 4.6 0.23 11.3 4.6 1.7 1 1 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus Porin_3 PF01459.22 PFH37461.1 - 9.4e-28 97.4 0.2 1.3e-27 97.0 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic porin WD40 PF00400.32 PFH37462.1 - 2.9e-12 46.9 12.4 0.00042 21.1 0.0 7.7 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH37462.1 - 7.5e-11 42.2 0.0 0.037 14.3 0.0 5.2 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 PFH37462.1 - 7.9e-05 21.9 4.2 0.45 9.5 0.6 4.8 5 1 0 5 5 5 3 Coatomer WD associated region PQQ PF01011.21 PFH37462.1 - 0.0053 16.6 0.7 0.38 10.8 0.2 3.4 2 1 1 3 3 3 1 PQQ enzyme repeat ANAPC3 PF12895.7 PFH37462.1 - 0.092 13.0 4.7 8.5 6.7 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-CCCH PF00642.24 PFH37463.1 - 3.3e-16 58.7 22.6 9.1e-06 25.5 3.1 4.5 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PFH37463.1 - 2.5e-08 33.7 20.8 0.00018 21.4 3.1 4.3 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 PFH37463.1 - 0.00015 21.4 1.9 0.00015 21.4 1.9 3.7 4 0 0 4 4 4 2 CCCH-type zinc finger Torus PF16131.5 PFH37463.1 - 0.014 16.1 1.0 0.014 16.1 1.0 3.0 2 1 1 3 3 3 0 Torus domain zf-CCCH_2 PF14608.6 PFH37463.1 - 0.49 11.0 11.5 6.1 7.5 0.8 3.8 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 PFH37463.1 - 0.9 9.8 10.2 2.8 8.2 0.4 3.0 2 1 1 3 3 3 0 Zinc-finger containing family TSP_1 PF00090.19 PFH37464.1 - 0.004 17.3 1.3 0.004 17.3 1.3 6.8 6 0 0 6 6 6 2 Thrombospondin type 1 domain zf-CCHC PF00098.23 PFH37465.1 - 1.3e-09 37.7 21.8 0.0025 17.8 1.0 4.6 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 PFH37465.1 - 0.1 12.3 22.3 0.4 10.5 0.9 4.3 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_2 PF13696.6 PFH37465.1 - 0.39 10.6 21.1 0.14 12.0 0.9 3.9 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_3 PF13917.6 PFH37465.1 - 1.3 9.1 19.3 16 5.5 0.4 4.6 3 1 1 4 4 4 0 Zinc knuckle ADK_lid PF05191.14 PFH37465.1 - 6 6.9 8.2 2.5 8.2 0.2 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-CCCH PF00642.24 PFH37466.1 - 6.5e-09 35.5 18.9 2.5e-06 27.2 1.3 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PFH37466.1 - 1.3e-05 25.0 17.7 0.013 15.5 1.1 3.7 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 PFH37466.1 - 0.00029 20.6 8.5 0.0055 16.5 2.2 2.9 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 PFH37466.1 - 0.0014 19.3 1.5 0.0014 19.3 1.5 3.5 2 1 1 4 4 4 2 Torus domain PAM2 PF07145.15 PFH37466.1 - 0.009 15.6 1.8 0.009 15.6 1.8 1.9 2 0 0 2 2 2 1 Ataxin-2 C-terminal region zf-CCCH_2 PF14608.6 PFH37466.1 - 0.11 13.0 17.6 0.33 11.5 4.3 3.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 PFH37466.1 - 4.7 7.0 10.9 4.7 7.0 0.1 4.1 4 0 0 4 4 4 0 Putative zinc-finger domain TMEM208_SND2 PF05620.11 PFH37467.1 - 9.6e-17 61.3 0.2 2.2e-16 60.1 0.2 1.6 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Helicase_C PF00271.31 PFH37468.1 - 5.9e-13 49.1 0.1 1.2e-12 48.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 PFH37468.1 - 2.7e-09 37.3 0.0 1.3e-08 35.1 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PFH37468.1 - 2.6e-06 27.7 0.0 6.6e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 PFH37468.1 - 1.8e-05 24.6 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 PFH37468.1 - 0.0066 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 PFH37468.1 - 0.027 13.8 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 PFH37468.1 - 0.05 13.9 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PFH37468.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 PFH37468.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Sigma54_activat PF00158.26 PFH37468.1 - 0.16 11.7 0.1 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 PFH37468.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Macoilin PF09726.9 PFH37468.1 - 6.5 5.2 7.3 11 4.4 7.3 1.3 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 PFH37469.1 - 6e-60 202.8 0.0 8.2e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH37469.1 - 4.8e-42 144.0 0.0 7.3e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH37469.1 - 6.1e-09 35.6 0.0 8.9e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PFH37469.1 - 0.071 11.9 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 PFH37469.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF1908 PF08926.11 PFH37469.1 - 7.5 5.5 8.4 13 4.8 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) Nop53 PF07767.11 PFH37470.1 - 0.059 12.8 9.3 0.089 12.2 9.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF3584 PF12128.8 PFH37470.1 - 1.3 6.4 6.2 1.8 6.0 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RL10P_insert PF17777.1 PFH37471.1 - 3.3e-23 81.5 0.2 1.1e-22 79.8 0.1 1.9 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 PFH37471.1 - 5.7e-20 71.7 7.4 5.7e-20 71.7 7.4 1.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.20 PFH37471.1 - 3.9e-16 59.0 0.2 9.2e-16 57.8 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 DUF2057 PF09829.9 PFH37471.1 - 0.82 9.8 3.1 5.3 7.2 3.1 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) WD40 PF00400.32 PFH37473.1 - 2.9e-41 138.7 14.7 3.3e-08 34.1 1.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH37473.1 - 0.00025 21.3 3.5 0.58 10.5 0.1 4.8 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PFH37473.1 - 0.0033 16.1 0.5 1.4 7.5 0.0 3.4 1 1 2 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 PFH37473.1 - 0.0091 15.4 0.0 5 6.3 0.0 2.8 1 1 2 3 3 3 3 WD40-like domain Nucleoporin_N PF08801.11 PFH37473.1 - 0.06 12.1 0.1 1.3 7.6 0.0 3.0 3 2 2 5 5 5 0 Nup133 N terminal like Lectin_C PF00059.21 PFH37474.1 - 4.9e-08 33.7 0.5 1.2e-07 32.4 0.1 1.9 2 0 0 2 2 2 1 Lectin C-type domain Alpha_GJ PF03229.13 PFH37474.1 - 0.024 15.2 0.1 0.024 15.2 0.1 3.5 4 0 0 4 4 4 0 Alphavirus glycoprotein J Thioredoxin PF00085.20 PFH37475.1 - 7.2e-41 138.4 0.0 3.2e-20 72.0 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 PFH37475.1 - 4.6e-17 62.5 0.0 9.3e-11 42.0 0.0 4.2 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 PFH37475.1 - 2.6e-07 30.3 0.0 0.0034 16.8 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 PFH37475.1 - 1e-05 25.9 0.1 0.017 15.5 0.0 3.2 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PFH37475.1 - 0.00063 19.9 0.0 0.0094 16.1 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.6 PFH37475.1 - 0.016 15.5 0.0 0.2 12.0 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like WD40 PF00400.32 PFH37477.1 - 0.044 14.7 0.3 8.4 7.5 0.0 4.6 6 0 0 6 6 6 0 WD domain, G-beta repeat Laminin_G_3 PF13385.6 PFH37478.1 - 3.2e-26 92.3 0.3 6.5e-26 91.3 0.3 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 PFH37478.1 - 0.00083 19.9 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain MtrD PF04207.12 PFH37479.1 - 0.069 12.8 0.3 0.093 12.4 0.3 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D PITH PF06201.13 PFH37480.1 - 6.5e-37 127.1 0.1 7.6e-37 126.9 0.1 1.0 1 0 0 1 1 1 1 PITH domain Peptidase_S9_N PF02897.15 PFH37480.1 - 0.0021 16.9 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 PFH37481.1 - 1.7e-08 34.1 0.3 4.1e-08 32.8 0.3 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PFH37481.1 - 1.8e-06 28.7 1.6 1.8e-06 28.7 1.6 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PFH37481.1 - 3.3e-05 23.5 0.0 0.088 12.3 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 PFH37481.1 - 0.004 16.8 0.2 0.0065 16.1 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.25 PFH37482.1 - 1.2e-26 93.6 0.0 2.9e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH37482.1 - 2.1e-10 40.3 0.0 4.7e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Activator_LAG-3 PF11498.8 PFH37482.1 - 1.1 8.2 18.9 2.4 7.1 18.9 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Carboxyl_trans PF01039.22 PFH37483.1 - 2.6e-153 511.2 0.0 3.7e-153 510.7 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 PFH37483.1 - 1.2e-51 175.9 0.0 1.9e-15 56.2 0.1 5.3 5 0 0 5 5 5 5 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 PFH37483.1 - 1.7e-48 165.0 0.5 3.8e-48 163.8 0.5 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PFH37483.1 - 5.5e-31 107.4 0.0 1.8e-30 105.7 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PFH37483.1 - 1.5e-19 70.1 0.0 3.1e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 PFH37483.1 - 5.1e-09 35.8 1.2 6.3e-09 35.5 0.1 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 PFH37483.1 - 6.3e-07 29.1 0.1 1.4e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 PFH37483.1 - 0.0019 18.0 0.0 0.025 14.4 0.0 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 PFH37483.1 - 0.0022 18.0 0.1 0.0045 17.1 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 PFH37483.1 - 0.038 13.5 0.0 0.093 12.3 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain PIN_6 PF17146.4 PFH37485.1 - 5.7e-21 74.8 0.0 1e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 PFH37485.1 - 6.7e-20 71.0 0.2 1.3e-19 70.1 0.2 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like HypA PF01155.19 PFH37485.1 - 0.12 12.4 0.2 0.32 11.0 0.2 1.7 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Nudix_N_2 PF14803.6 PFH37485.1 - 0.25 11.3 2.7 2.2 8.2 0.1 2.7 2 0 0 2 2 2 0 Nudix N-terminal Nop14 PF04147.12 PFH37485.1 - 0.41 8.8 5.7 0.5 8.5 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family SpoU_methylase PF00588.19 PFH37486.1 - 1.2e-24 87.1 0.1 2.2e-24 86.2 0.1 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family PP2C PF00481.21 PFH37487.1 - 1.2e-31 110.3 0.1 2.6e-31 109.2 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C RRM_1 PF00076.22 PFH37488.1 - 5.9e-11 42.0 0.1 5.9e-09 35.6 0.0 3.6 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH37488.1 - 3.1e-05 24.0 0.0 0.00032 20.8 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif GNAT_acetyltr_2 PF13718.6 PFH37489.1 - 8.3e-79 264.2 0.0 1.8e-56 191.1 0.0 2.5 1 1 1 2 2 2 2 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 PFH37489.1 - 8.3e-56 188.6 0.0 1.7e-55 187.6 0.0 1.6 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 PFH37489.1 - 1.1e-48 166.1 1.6 2.7e-48 164.7 0.0 2.2 2 0 0 2 2 2 1 Possible tRNA binding domain DUF1726 PF08351.11 PFH37489.1 - 4e-32 110.0 0.0 9e-32 108.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 PFH37489.1 - 0.00071 19.3 0.1 0.0029 17.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 PFH37489.1 - 0.032 14.5 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family GHMP_kinases_N PF00288.26 PFH37489.1 - 0.039 14.2 1.8 4.5 7.6 0.0 2.8 2 0 0 2 2 2 0 GHMP kinases N terminal domain Nop14 PF04147.12 PFH37489.1 - 0.071 11.3 6.1 0.15 10.3 6.1 1.4 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 PFH37489.1 - 0.34 8.9 11.0 0.56 8.2 11.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 PFH37489.1 - 1.5 7.0 9.0 2.6 6.2 9.0 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 PFH37489.1 - 2.6 7.3 10.8 4.8 6.4 10.8 1.3 1 0 0 1 1 1 0 NOA36 protein SIR4_SID PF16991.5 PFH37489.1 - 3.2 7.8 6.6 1.2 9.2 3.3 1.9 2 0 0 2 2 2 0 Sir4 SID domain Pkinase PF00069.25 PFH37490.1 - 4.3e-69 232.8 0.1 5.7e-69 232.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH37490.1 - 7.8e-42 143.3 0.1 1.3e-41 142.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 PFH37490.1 - 3.2e-32 110.8 5.3 1.4e-11 44.7 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 PFH37490.1 - 1.5e-29 99.3 8.3 6e-06 25.4 0.1 5.9 6 0 0 6 6 6 5 EF hand EF-hand_5 PF13202.6 PFH37490.1 - 3.1e-25 86.5 11.1 6.4e-06 25.4 0.1 5.4 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 PFH37490.1 - 2.6e-23 79.9 10.8 0.00036 20.2 0.1 6.4 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 PFH37490.1 - 2.9e-15 55.8 15.6 0.00013 21.8 0.3 6.4 3 3 3 6 6 6 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PFH37490.1 - 5.5e-09 36.3 0.6 0.0022 18.3 0.0 3.5 3 0 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 PFH37490.1 - 3.8e-08 33.0 0.0 5.7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PFH37490.1 - 4.3e-06 26.2 0.1 8e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.7 PFH37490.1 - 0.0022 17.9 4.9 0.33 10.9 0.0 3.3 2 2 2 4 4 3 2 Cytoskeletal-regulatory complex EF hand RIO1 PF01163.22 PFH37490.1 - 0.0029 17.3 0.3 0.0049 16.5 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 PFH37490.1 - 0.01 14.7 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase EF-hand_9 PF14658.6 PFH37490.1 - 0.02 15.2 0.3 0.079 13.3 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain YrbL-PhoP_reg PF10707.9 PFH37490.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 PFH37490.1 - 0.035 14.0 0.0 0.17 11.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF892 PF05974.12 PFH37490.1 - 0.084 12.9 1.7 0.096 12.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Choline_kinase PF01633.20 PFH37490.1 - 0.096 12.3 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Spec3 PF15795.5 PFH37491.1 - 0.047 14.2 2.6 0.047 14.2 2.6 2.7 1 1 2 3 3 3 0 Ectodermal ciliogenesis protein Borrelia_P13 PF05628.12 PFH37491.1 - 0.2 11.6 0.6 0.31 11.0 0.6 1.2 1 0 0 1 1 1 0 Borrelia membrane protein P13 Ferric_reduct PF01794.19 PFH37492.1 - 1.1 9.4 8.2 0.43 10.7 4.9 2.0 1 1 1 2 2 2 0 Ferric reductase like transmembrane component GWT1 PF06423.12 PFH37492.1 - 2.1 8.5 9.1 3.7 7.7 4.8 2.0 1 1 0 2 2 2 0 GWT1 AAA_19 PF13245.6 PFH37493.1 - 1.4e-06 28.7 0.0 1.7e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Myosin_head PF00063.21 PFH37493.1 - 0.00019 19.8 0.0 2.3 6.3 0.0 3.8 4 0 0 4 4 4 2 Myosin head (motor domain) rpo132 PF12415.8 PFH37493.1 - 0.015 14.5 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase CDC45 PF02724.14 PFH37493.1 - 0.65 8.2 3.5 1 7.6 3.5 1.3 1 0 0 1 1 1 0 CDC45-like protein SNAP PF14938.6 PFH37494.1 - 8.5e-78 261.6 11.9 9.8e-78 261.4 11.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 PFH37494.1 - 0.022 14.8 9.3 0.91 9.7 0.2 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 PFH37494.1 - 0.039 13.8 4.9 0.2 11.6 1.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 PFH37494.1 - 0.7 10.2 17.2 0.5 10.7 4.2 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH37494.1 - 0.95 10.2 4.4 50 4.8 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 PFH37494.1 - 6.8 7.1 13.6 8.4 6.8 0.2 5.2 5 2 0 5 5 5 0 Tetratricopeptide repeat Mito_carr PF00153.27 PFH37495.1 - 1.2e-14 53.9 6.2 3.6e-06 26.8 0.1 5.2 4 2 0 4 4 4 3 Mitochondrial carrier protein Aminotran_5 PF00266.19 PFH37496.1 - 3.5e-46 157.8 0.0 6.8e-46 156.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V GTP_EFTU PF00009.27 PFH37497.1 - 7.1e-48 162.7 0.0 1.3e-47 161.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 PFH37497.1 - 1e-13 51.1 0.0 3.3e-06 27.0 0.0 2.8 3 0 0 3 3 3 2 Elongation factor G C-terminus EFG_II PF14492.6 PFH37497.1 - 1e-12 48.0 0.0 2.5e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 PFH37497.1 - 0.00016 21.5 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 PFH37497.1 - 0.0032 17.8 0.0 0.0078 16.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PFH37497.1 - 0.031 14.4 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Tyr_Deacylase PF02580.16 PFH37499.1 - 5.1e-46 156.8 0.0 6.2e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase LpoB PF13036.6 PFH37499.1 - 0.094 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB Thioredoxin_6 PF13848.6 PFH37499.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain RhoGAP-FF1 PF16512.5 PFH37499.1 - 0.15 12.8 0.1 0.31 11.8 0.1 1.5 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain Alba PF01918.21 PFH37500.1 - 3.3e-05 23.6 0.0 4.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Alba Herpes_UL3 PF03369.13 PFH37500.1 - 0.082 13.4 0.2 0.16 12.5 0.1 1.5 1 1 0 1 1 1 0 Herpesvirus UL3 protein Neurochondrin PF05536.11 PFH37501.1 - 2.1e-05 23.1 0.0 5.9e-05 21.6 0.0 1.6 1 1 0 1 1 1 1 Neurochondrin Tubulin PF00091.25 PFH37502.1 - 3.4e-62 210.2 0.0 4.5e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PFH37502.1 - 6.2e-46 155.7 0.1 3.8e-45 153.1 0.0 2.0 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 PFH37502.1 - 0.00034 20.3 0.0 0.00069 19.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MutS_V PF00488.21 PFH37503.1 - 3e-15 56.7 0.0 3.1e-08 33.9 0.0 3.3 3 0 0 3 3 3 3 MutS domain V MutS_I PF01624.20 PFH37503.1 - 0.00012 22.3 0.0 0.0003 21.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain I Ribosomal_S9 PF00380.19 PFH37504.1 - 2.3e-35 121.7 0.1 3.7e-35 121.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Tail_VII PF17091.5 PFH37504.1 - 0.13 12.1 0.6 8.9 6.3 0.3 2.3 2 0 0 2 2 2 0 Inovirus G7P protein DUF3876 PF12992.7 PFH37505.1 - 0.076 13.1 0.0 0.25 11.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3876) RabGAP-TBC PF00566.18 PFH37506.1 - 9.3e-62 208.5 0.6 1.4e-61 207.9 0.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SF-assemblin PF06705.11 PFH37507.1 - 2.1e-62 210.7 25.5 2.5e-62 210.4 25.5 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Gp58 PF07902.11 PFH37507.1 - 0.0026 16.1 4.1 0.0037 15.6 4.1 1.2 1 0 0 1 1 1 1 gp58-like protein TPR_2 PF07719.17 PFH37507.1 - 0.5 10.6 2.6 5.3 7.4 0.9 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Nup54 PF13874.6 PFH37507.1 - 0.52 10.4 19.9 0.032 14.3 5.8 2.7 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 FtsH_ext PF06480.15 PFH37509.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 FtsH Extracellular Proteasome PF00227.26 PFH37512.1 - 1.3e-46 158.5 0.0 1.6e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit BTB PF00651.31 PFH37513.1 - 2.8e-15 56.5 0.0 2.7e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain UPF0565 PF10561.9 PFH37513.1 - 0.047 12.9 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Asn_synthase PF00733.21 PFH37513.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase AP2 PF00847.20 PFH37517.1 - 4.4e-29 100.5 34.6 1.8e-10 40.9 0.3 5.8 5 0 0 5 5 5 5 AP2 domain ACDC PF14733.6 PFH37517.1 - 2.7e-05 24.4 0.1 0.00011 22.4 0.1 1.8 2 0 0 2 2 2 1 AP2-coincident C-terminal cNMP_binding PF00027.29 PFH37518.1 - 5.6e-91 298.8 2.1 1.1e-20 73.5 0.1 6.5 6 0 0 6 6 6 6 Cyclic nucleotide-binding domain EF-hand_1 PF00036.32 PFH37518.1 - 0.00034 20.0 1.4 0.042 13.4 0.2 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PFH37518.1 - 0.0004 20.1 1.4 0.58 10.2 0.1 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_11 PF08976.11 PFH37518.1 - 0.0075 17.1 0.2 0.067 14.1 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain DUF410 PF04190.13 PFH37519.1 - 1.4e-42 146.2 0.0 1.7e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) MCM_lid PF17855.1 PFH37519.1 - 0.17 12.3 0.1 1.7 9.2 0.0 2.3 2 0 0 2 2 2 0 MCM AAA-lid domain CKS PF01111.19 PFH37520.1 - 4.4e-22 78.1 0.1 1.3e-21 76.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit PARM PF17061.5 PFH37520.1 - 1.2 9.3 13.0 1.6 8.8 13.0 1.1 1 0 0 1 1 1 0 PARM zf-CCCH PF00642.24 PFH37521.1 - 0.0021 17.9 1.0 0.01 15.7 0.7 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PFH37521.1 - 0.017 15.1 2.1 0.13 12.3 2.3 2.5 2 0 0 2 2 2 0 Zinc finger domain Pyr_redox_2 PF07992.14 PFH37522.1 - 9.7e-52 176.0 1.9 1.7e-51 175.2 1.9 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PFH37522.1 - 5.3e-29 100.7 0.2 2.8e-28 98.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PFH37522.1 - 2.6e-14 53.5 9.2 1.8e-12 47.6 0.6 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PFH37522.1 - 1.2e-10 41.1 6.3 7.9e-06 25.3 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PFH37522.1 - 3.9e-10 39.7 0.3 5.8e-10 39.1 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 PFH37522.1 - 2.1e-07 30.4 0.1 1.4e-06 27.7 0.0 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 PFH37522.1 - 8.7e-05 22.7 6.4 0.0052 17.0 3.8 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PFH37522.1 - 0.00032 19.5 1.6 0.00081 18.2 1.6 1.7 1 0 0 1 1 1 1 HI0933-like protein K_oxygenase PF13434.6 PFH37522.1 - 0.00032 19.9 0.1 0.00032 19.9 0.1 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 PFH37522.1 - 0.0009 18.5 0.5 0.0024 17.1 0.4 1.7 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 PFH37522.1 - 0.0017 17.7 4.4 0.75 9.1 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 PFH37522.1 - 0.0023 17.1 16.5 0.12 11.4 12.7 3.2 2 1 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 PFH37522.1 - 0.0093 15.2 2.8 1.5 8.0 0.5 2.3 2 0 0 2 2 2 2 FAD binding domain 2-Hacid_dh_C PF02826.19 PFH37522.1 - 0.01 15.2 0.6 0.45 9.8 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 PFH37522.1 - 0.024 15.1 0.2 2.2 8.8 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 PFH37522.1 - 0.042 14.3 0.9 8.6 6.9 0.1 2.7 3 0 0 3 3 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 PFH37522.1 - 0.13 12.3 0.9 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 PFH37522.1 - 0.19 11.6 5.0 0.36 10.7 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 PFH37522.1 - 0.21 11.6 2.0 25 4.8 0.1 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 PFH37522.1 - 0.28 10.2 1.4 0.66 9.0 1.4 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 PFH37522.1 - 7.1 6.1 17.9 0.065 12.8 7.9 2.6 3 1 1 4 4 4 0 FAD dependent oxidoreductase EF1_GNE PF00736.19 PFH37523.1 - 1.6e-32 111.6 3.9 1.6e-32 111.6 3.9 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain Stm1_N PF09598.10 PFH37523.1 - 0.012 16.5 0.8 0.012 16.5 0.8 2.3 3 0 0 3 3 3 0 Stm1 DNA_pol3_a_NII PF11490.8 PFH37523.1 - 0.75 9.7 10.1 1.2 9.0 1.3 2.2 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II TRAP_alpha PF03896.16 PFH37523.1 - 2.1 7.5 8.8 5.6 6.1 0.6 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Kri1_C PF12936.7 PFH37524.1 - 4.3e-26 90.9 0.7 4.3e-26 90.9 0.7 3.0 2 0 0 2 2 2 1 KRI1-like family C-terminal Kri1 PF05178.12 PFH37524.1 - 4.8e-17 62.4 7.3 4.8e-17 62.4 7.3 4.4 3 3 0 3 3 3 1 KRI1-like family ZZ PF00569.17 PFH37524.1 - 6e-06 26.0 3.9 1e-05 25.3 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 PFH37524.1 - 0.013 15.8 3.5 0.013 15.8 3.5 1.7 2 0 0 2 2 2 0 C1 domain DUF4503 PF14951.6 PFH37524.1 - 0.48 8.8 1.6 0.77 8.2 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Phostensin PF13914.6 PFH37525.1 - 0.0058 17.3 0.3 0.0098 16.5 0.3 1.3 1 0 0 1 1 1 1 Phostensin PP1-binding and SH3-binding region PH PF00169.29 PFH37525.1 - 0.032 14.8 0.0 0.077 13.5 0.0 1.6 1 0 0 1 1 1 0 PH domain Phytochelatin_C PF09328.10 PFH37525.1 - 0.13 11.6 3.8 0.44 9.8 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1984) PH_13 PF16652.5 PFH37525.1 - 0.24 11.2 1.1 5.1 6.9 0.0 2.1 1 1 1 2 2 2 0 Pleckstrin homology domain EF-hand_7 PF13499.6 PFH37526.1 - 0.0003 21.2 2.0 2.3 8.7 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH37526.1 - 0.002 17.9 0.1 3.5 7.8 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain DUF5580 PF17743.1 PFH37526.1 - 0.032 12.8 0.0 0.055 12.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Stealth_CR3 PF17102.5 PFH37526.1 - 0.094 12.6 0.1 0.28 11.1 0.1 1.8 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 EF-hand_1 PF00036.32 PFH37526.1 - 0.15 11.7 0.1 6.7 6.5 0.0 3.4 4 0 0 4 4 4 0 EF hand Acetyltransf_1 PF00583.25 PFH37528.1 - 3.6e-07 30.4 0.0 7.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PFH37528.1 - 4.8e-07 29.8 0.0 9.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PFH37528.1 - 1.6e-06 28.4 0.0 3.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PFH37528.1 - 0.041 14.0 0.2 0.08 13.0 0.2 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CS PF04969.16 PFH37529.1 - 5.5e-10 40.1 0.0 7.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 CS domain DEAD PF00270.29 PFH37530.1 - 2.3e-29 102.4 0.2 4.1e-27 95.1 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH37530.1 - 2.2e-27 95.6 0.0 9.3e-26 90.4 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 PFH37530.1 - 5.2e-05 22.2 0.0 0.023 13.5 0.0 2.4 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Bunya_NS-S PF01104.17 PFH37530.1 - 0.17 11.7 0.6 0.37 10.6 0.1 1.7 2 0 0 2 2 2 0 Bunyavirus non-structural protein NS-s GCP5-Mod21 PF14609.6 PFH37530.1 - 3.9 5.7 7.6 2.6 6.3 5.4 1.6 1 1 1 2 2 2 0 gamma-Tubulin ring complex non-core subunit mod21 BUD22 PF09073.10 PFH37531.1 - 0.0092 15.4 24.9 0.012 15.0 24.9 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 PFH37531.1 - 0.079 11.2 26.0 0.09 11.0 26.0 1.0 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 PFH37531.1 - 0.26 10.8 10.1 0.35 10.4 10.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SGT1 PF07093.11 PFH37531.1 - 5 5.4 11.7 6.4 5.1 11.7 1.1 1 0 0 1 1 1 0 SGT1 protein DNA_pol_phi PF04931.13 PFH37531.1 - 5.4 5.0 30.0 8.5 4.3 30.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Ank_2 PF12796.7 PFH37532.1 - 2.9e-23 82.2 2.3 2.4e-09 37.6 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PFH37532.1 - 3.3e-23 81.7 0.9 1.5e-09 38.2 0.1 3.9 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH37532.1 - 3.2e-20 70.1 0.3 0.00057 20.1 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 PFH37532.1 - 1e-19 70.3 4.1 1.1e-06 28.8 0.1 4.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 PFH37532.1 - 5.4e-14 51.9 5.3 0.004 17.5 0.2 5.4 5 0 0 5 5 5 4 Ankyrin repeat AMP-binding PF00501.28 PFH37534.1 - 5.1e-36 124.2 0.0 7e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PFH37534.1 - 5.7e-14 52.9 0.0 1.3e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PTH2 PF01981.16 PFH37535.1 - 1.8e-15 57.2 0.1 3.4e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Acetyltransf_7 PF13508.7 PFH37535.1 - 0.00014 22.2 0.0 0.00029 21.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PFH37535.1 - 0.0016 18.4 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PFH37535.1 - 0.0019 18.4 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family E1-E2_ATPase PF00122.20 PFH37536.1 - 4.1e-29 101.4 0.1 4.1e-29 101.4 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 PFH37536.1 - 6.2e-14 52.8 0.0 7.4e-05 23.1 0.0 3.8 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 PFH37536.1 - 1.5e-11 44.5 0.0 1.7e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase PF13246.6 PFH37536.1 - 1.5e-05 25.0 0.0 4.2e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF3273 PF11677.8 PFH37537.1 - 4.1e-68 229.6 15.2 5.6e-68 229.1 15.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Actin PF00022.19 PFH37538.1 - 2.8e-88 296.3 0.0 3.8e-87 292.5 0.0 1.9 1 1 0 1 1 1 1 Actin Ribosomal_S24e PF01282.19 PFH37538.1 - 0.015 15.3 0.0 0.085 12.8 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S24e F_actin_cap_B PF01115.17 PFH37539.1 - 1.9e-66 224.1 0.0 2.3e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Peptidase_M15_2 PF05951.13 PFH37539.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) zf-RanBP PF00641.18 PFH37540.1 - 9e-17 60.1 21.6 7.5e-09 34.8 5.5 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF35_N PF12172.8 PFH37540.1 - 0.16 11.9 6.6 3.2 7.7 0.2 3.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-P11 PF03854.14 PFH37540.1 - 0.2 11.4 3.5 0.29 10.8 0.5 2.1 2 0 0 2 2 2 0 P-11 zinc finger DZR PF12773.7 PFH37540.1 - 0.28 11.2 7.4 1.2 9.2 7.3 2.0 1 1 1 2 2 2 0 Double zinc ribbon RecR PF02132.15 PFH37540.1 - 1.4 8.5 10.6 0.049 13.2 1.2 2.3 2 0 0 2 2 2 0 RecR protein HSP70 PF00012.20 PFH37541.1 - 3.5e-106 355.8 0.2 2e-96 323.6 0.0 2.6 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 PFH37541.1 - 0.003 16.4 0.7 0.05 12.4 0.0 2.7 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 PFH37541.1 - 0.0055 16.4 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Metallophos PF00149.28 PFH37542.1 - 0.028 14.9 0.0 0.075 13.5 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase tRNA-synt_2b PF00587.25 PFH37544.1 - 1.7e-19 70.5 0.0 4.1e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Lactamase_B_6 PF16661.5 PFH37545.1 - 8.7e-11 41.6 0.0 0.00019 20.9 0.0 3.0 3 1 0 3 3 3 2 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 PFH37545.1 - 1.6e-06 28.4 0.0 0.0025 18.1 0.0 2.5 2 0 0 2 2 2 2 Beta-Casp domain Herpes_PAP PF03325.13 PFH37545.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein WD40 PF00400.32 PFH37546.1 - 4.2e-17 62.2 14.6 0.0079 17.0 0.2 9.7 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH37546.1 - 5.9e-05 23.3 0.0 3.9 7.8 0.0 4.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Diphthamide_syn PF01866.17 PFH37548.1 - 2.6e-20 73.1 0.0 1.3e-11 44.5 0.0 2.9 3 0 0 3 3 3 2 Putative diphthamide synthesis protein Peptidase_S9 PF00326.21 PFH37549.1 - 7.9e-14 51.6 0.1 5.8e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 PFH37549.1 - 0.25 10.1 0.0 17 4.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain MMR_HSR1 PF01926.23 PFH37551.1 - 2.5e-11 43.6 0.0 8.1e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PFH37551.1 - 2.6e-07 30.3 0.1 0.036 13.6 0.0 3.1 2 1 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PFH37551.1 - 2.4e-06 27.6 0.0 4.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 PFH37551.1 - 0.029 13.9 0.0 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 PFH37551.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 PFH37551.1 - 0.089 12.8 0.2 19 5.3 0.1 3.0 2 1 1 3 3 3 0 Dynamin family Methyltransf_25 PF13649.6 PFH37552.1 - 1.7e-11 44.7 0.1 4.9e-11 43.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PFH37552.1 - 2.1e-09 37.4 0.0 4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PFH37552.1 - 4.6e-09 36.8 0.0 1.2e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PFH37552.1 - 8.1e-09 35.3 0.1 1.3e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 PFH37552.1 - 1e-06 28.7 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 PFH37552.1 - 9.1e-05 21.5 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 PFH37552.1 - 0.00025 20.4 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 PFH37552.1 - 0.00055 19.5 0.1 0.001 18.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 PFH37552.1 - 0.00068 19.6 0.1 0.0012 18.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 PFH37552.1 - 0.0027 17.3 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.19 PFH37552.1 - 0.0031 17.3 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 PFH37552.1 - 0.0099 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 PFH37552.1 - 0.019 16.0 0.0 0.044 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 PFH37552.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 PFH37552.1 - 0.045 14.5 0.0 0.081 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 PFH37552.1 - 0.055 12.8 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 PFH37552.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 PFH37552.1 - 0.096 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 zf-HC5HC2H PF13771.6 PFH37553.1 - 0.0054 17.0 0.1 0.012 15.8 0.1 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain C1_2 PF03107.16 PFH37553.1 - 0.019 15.3 2.2 0.042 14.2 2.2 1.6 1 0 0 1 1 1 0 C1 domain zf-RING-like PF08746.11 PFH37553.1 - 0.019 15.3 1.5 0.019 15.3 1.5 2.1 2 0 0 2 2 2 0 RING-like domain FXR_C1 PF16096.5 PFH37553.1 - 0.022 14.9 1.1 0.022 14.9 1.1 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 tRNA-synt_2c PF01411.19 PFH37554.1 - 2.5e-205 683.2 0.0 3.4e-205 682.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 PFH37554.1 - 5.7e-14 51.9 0.0 1.3e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 PFH37554.1 - 4.5e-06 27.1 4.1 4.5e-06 27.1 4.1 2.3 2 0 0 2 2 2 1 DHHA1 domain KMP11 PF03037.16 PFH37554.1 - 0.049 14.4 1.6 0.11 13.3 0.6 2.1 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 2-oxoacid_dh PF00198.23 PFH37555.1 - 2.3e-79 266.1 0.3 3.1e-79 265.7 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PFH37555.1 - 6.8e-19 67.5 0.2 1.5e-18 66.4 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 PFH37555.1 - 1.8e-08 34.1 0.1 0.00024 20.9 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 PFH37555.1 - 0.00023 21.8 0.3 0.12 13.1 0.0 2.6 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 PFH37555.1 - 0.062 12.5 0.1 0.29 10.3 0.0 2.1 2 1 0 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion TIP49 PF06068.13 PFH37556.1 - 1.4e-158 527.7 0.2 1.8e-158 527.4 0.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 PFH37556.1 - 1.7e-22 79.3 0.2 5.4e-22 77.7 0.2 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 PFH37556.1 - 9.2e-09 35.8 0.1 0.00012 22.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PFH37556.1 - 1.6e-06 28.5 0.0 0.073 13.4 0.0 2.6 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.12 PFH37556.1 - 2.5e-06 27.3 0.2 0.0001 22.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PFH37556.1 - 0.00017 21.6 0.1 0.064 13.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PFH37556.1 - 0.00082 19.8 0.0 0.006 17.0 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 PFH37556.1 - 0.0017 17.8 0.4 0.077 12.4 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 PFH37556.1 - 0.0055 16.4 0.2 3.8 7.2 0.1 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 PFH37556.1 - 0.0076 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 PFH37556.1 - 0.027 14.8 0.8 0.88 9.9 0.8 2.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PFH37556.1 - 0.047 13.3 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 PFH37556.1 - 0.054 13.5 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 PFH37556.1 - 0.055 13.5 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 PFH37556.1 - 0.085 12.3 0.3 0.2 11.1 0.3 1.6 1 0 0 1 1 1 0 PhoH-like protein AFG1_ATPase PF03969.16 PFH37556.1 - 0.088 11.7 0.7 1.2 8.0 0.1 2.2 2 0 0 2 2 2 0 AFG1-like ATPase AAA_28 PF13521.6 PFH37556.1 - 0.088 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 PFH37556.1 - 0.096 13.2 0.0 0.16 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PFH37556.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 PFH37556.1 - 0.15 11.8 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_pol_Rpc4 PF05132.14 PFH37557.1 - 1.2e-13 51.7 27.1 5.5e-12 46.4 13.3 5.7 3 1 0 3 3 3 1 RNA polymerase III RPC4 FtsJ PF01728.19 PFH37558.1 - 3.8e-12 46.7 0.0 6.4e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 PFH37558.1 - 0.00015 22.4 0.1 0.00032 21.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PFH37558.1 - 0.00024 21.7 0.2 0.00051 20.6 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain S4 PF01479.25 PFH37558.1 - 0.00027 20.6 0.4 0.00074 19.2 0.4 1.8 1 0 0 1 1 1 1 S4 domain PrmA PF06325.13 PFH37558.1 - 0.0018 17.7 0.0 0.0027 17.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 PFH37558.1 - 0.014 15.3 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 PFH37558.1 - 0.05 14.6 0.0 0.13 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_1 PF00175.21 PFH37559.1 - 6.4e-17 62.2 0.0 3.7e-11 43.6 0.0 2.8 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.25 PFH37559.1 - 3.9e-16 59.5 0.2 1.4e-15 57.8 0.2 2.1 1 1 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 PFH37559.1 - 1.1e-06 28.4 0.0 3.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_6 PF08030.12 PFH37559.1 - 0.2 11.8 0.0 0.52 10.4 0.0 1.7 2 0 0 2 2 2 0 Ferric reductase NAD binding domain zf-C3HC4_3 PF13920.6 PFH37560.1 - 2.1e-10 40.3 7.9 4.6e-10 39.2 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PFH37560.1 - 3.5e-05 23.6 8.5 8.2e-05 22.4 8.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PFH37560.1 - 0.0094 15.9 9.4 0.021 14.8 9.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 PFH37560.1 - 0.017 15.4 10.3 0.035 14.4 10.3 1.6 1 0 0 1 1 1 0 Ring finger domain MS_channel PF00924.18 PFH37561.1 - 3.2e-14 53.0 0.3 4.5e-14 52.5 0.3 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel AsnA PF03590.15 PFH37562.1 - 0.00086 19.1 1.9 0.0031 17.3 0.2 2.8 2 0 0 2 2 2 1 Aspartate-ammonia ligase DUF713 PF05218.14 PFH37562.1 - 4.7 6.9 6.8 23 4.6 1.8 4.5 2 0 0 2 2 2 0 Protein of unknown function (DUF713) zf-CCCH PF00642.24 PFH37563.1 - 6.8e-12 45.0 18.4 0.00011 22.1 1.6 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PFH37563.1 - 8.5e-09 35.0 21.4 2.1e-05 24.2 2.5 3.4 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 PFH37563.1 - 6.1e-06 26.9 11.8 0.00069 20.3 0.4 3.3 1 1 2 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 PFH37563.1 - 0.018 15.1 5.5 0.018 15.1 5.5 4.3 4 0 0 4 4 4 0 Zinc finger domain zf-CCCH_2 PF14608.6 PFH37563.1 - 1.7 9.2 19.0 1.8 9.1 3.3 3.5 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger BCDHK_Adom3 PF10436.9 PFH37565.1 - 1.3e-22 80.4 0.0 2e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase MCM PF00493.23 PFH37567.1 - 3.3e-89 297.8 0.0 1.8e-88 295.4 0.0 2.0 1 1 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PFH37567.1 - 4.5e-29 100.9 0.2 8e-29 100.1 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PFH37567.1 - 9.4e-24 83.7 1.3 3e-23 82.0 1.3 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 PFH37567.1 - 2.8e-06 26.9 0.1 6e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PFH37567.1 - 4.2e-05 23.6 0.0 0.00028 20.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 PFH37567.1 - 7.2e-05 23.3 0.1 0.00033 21.2 0.1 2.1 1 1 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.11 PFH37567.1 - 0.00039 20.3 0.0 0.00084 19.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 PFH37567.1 - 0.0081 15.9 0.0 0.67 9.6 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain IGFL PF14653.6 PFH37567.1 - 0.17 11.9 1.9 0.36 10.8 1.9 1.5 1 0 0 1 1 1 0 Insulin growth factor-like family Atg14 PF10186.9 PFH37568.1 - 0.42 9.6 19.6 0.94 8.5 19.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 PFH37568.1 - 1.9 8.5 13.9 1.5 8.8 7.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) U1snRNP70_N PF12220.8 PFH37568.1 - 1.9 9.2 11.4 0.69 10.6 3.6 3.4 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Baculo_PEP_C PF04513.12 PFH37568.1 - 2 8.5 20.5 1.5 8.9 5.6 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_Mu_Gam PF07352.12 PFH37568.1 - 2.3 8.1 13.7 3.2 7.7 0.9 2.7 1 1 2 3 3 3 0 Bacteriophage Mu Gam like protein V_ATPase_I PF01496.19 PFH37568.1 - 3.7 5.3 9.5 7.3 4.4 9.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 PFH37568.1 - 4.2 6.2 7.0 6.3 5.6 7.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein RasGAP_C PF03836.15 PFH37568.1 - 7.2 6.7 12.2 16 5.7 12.2 1.5 1 0 0 1 1 1 0 RasGAP C-terminus Prominin PF05478.11 PFH37568.1 - 10 4.0 13.8 17 3.2 13.1 1.4 1 1 0 1 1 1 0 Prominin Ras PF00071.22 PFH37569.1 - 3.5e-54 182.8 0.1 4.3e-54 182.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH37569.1 - 1e-33 116.1 0.0 5.2e-33 113.8 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH37569.1 - 6.3e-13 48.6 0.0 8.2e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PFH37569.1 - 7.7e-07 28.8 0.0 2.6e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PFH37569.1 - 5.2e-05 23.2 0.2 0.096 12.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PFH37569.1 - 0.00021 21.4 0.0 0.00031 20.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PFH37569.1 - 0.0024 17.3 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 PFH37569.1 - 0.013 15.9 0.1 0.02 15.3 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain Ipi1_N PF12333.8 PFH37570.1 - 0.19 12.3 0.6 2.5 8.7 0.0 2.9 2 1 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TRAP_alpha PF03896.16 PFH37570.1 - 7.4 5.7 7.3 27 3.8 7.3 2.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cytochrom_C PF00034.21 PFH37572.1 - 1.6e-12 48.4 0.0 2.5e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 PFH37572.1 - 8.1e-07 29.3 2.0 2.2e-06 27.9 2.0 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 PFH37572.1 - 0.00065 19.4 0.1 0.0026 17.5 0.0 1.8 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 PFH37572.1 - 0.039 13.5 0.1 0.054 13.1 0.1 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Acetyltransf_1 PF00583.25 PFH37573.1 - 5.3e-10 39.6 0.0 7.5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PFH37573.1 - 8.5e-06 25.7 0.1 1.4e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PFH37573.1 - 1.1e-05 25.8 0.0 1.6e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PFH37573.1 - 0.00052 19.9 0.0 0.00082 19.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Ribosom_S12_S23 PF00164.25 PFH37574.1 - 4.3e-27 94.0 1.0 7e-27 93.3 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Presenilin PF01080.17 PFH37575.1 - 0.13 11.0 4.2 0.14 10.9 4.2 1.0 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 PFH37575.1 - 0.19 11.5 2.4 0.18 11.5 2.4 1.1 1 0 0 1 1 1 0 Connexin PRP3 PF08572.10 PFH37576.1 - 5.3e-62 209.5 15.2 5.3e-62 209.5 15.2 2.8 3 0 0 3 3 3 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 PFH37576.1 - 3.6e-36 124.4 2.5 7.1e-36 123.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) ATP-synt_ab PF00006.25 PFH37577.1 - 1.6e-65 220.7 0.0 2.2e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 PFH37577.1 - 4.7e-11 43.1 0.6 8.8e-11 42.2 0.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain CNDH2_M PF16869.5 PFH37578.1 - 6.8 7.4 7.3 1.7 9.3 0.2 2.9 2 1 1 3 3 3 0 PF16858 ubiquitin PF00240.23 PFH37579.1 - 7e-273 881.1 39.1 2.9e-33 113.4 0.3 8.0 8 0 0 8 8 8 8 Ubiquitin family Rad60-SLD PF11976.8 PFH37579.1 - 5.3e-127 413.8 43.9 3.8e-15 55.5 0.4 8.0 8 0 0 8 8 8 8 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PFH37579.1 - 2.8e-48 162.3 18.4 0.00044 20.7 0.1 10.2 8 8 0 8 8 8 8 Ubiquitin-like domain TBK1_ULD PF18396.1 PFH37579.1 - 3.8e-31 106.9 11.4 0.061 13.2 0.0 8.2 8 0 0 8 8 8 8 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PFH37579.1 - 7.4e-27 93.6 9.6 0.29 11.3 0.0 9.1 8 0 0 8 8 8 8 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 PFH37579.1 - 1.2e-25 89.7 17.7 0.2 12.0 0.1 8.1 8 0 0 8 8 8 8 Ubiquitin-like domain DUF2407 PF10302.9 PFH37579.1 - 9.1e-24 84.0 4.7 1.2 9.7 0.0 8.2 1 1 2 8 8 8 8 DUF2407 ubiquitin-like domain DUF2870 PF11069.8 PFH37579.1 - 2.2e-11 44.0 0.0 71 3.9 0.0 8.7 8 0 0 8 8 8 0 Protein of unknown function (DUF2870) UDP-g_GGTase PF06427.11 PFH37579.1 - 4.9e-10 39.5 10.4 18 5.5 0.0 7.6 8 0 0 8 8 8 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 PFH37579.1 - 2e-08 33.9 0.3 60 3.0 0.0 7.6 8 0 0 8 8 8 0 Protein of unknown function (DUF969) Ubiquitin_4 PF18036.1 PFH37579.1 - 3.6e-07 30.1 50.3 60 3.8 0.0 15.5 16 0 0 16 16 16 0 Ubiquitin-like domain ORF11CD3 PF10549.9 PFH37579.1 - 1.4e-06 28.3 0.0 2.2e+02 2.1 0.0 8.0 8 0 0 8 8 8 0 ORF11CD3 domain Big_7 PF17957.1 PFH37579.1 - 8.5e-05 23.2 0.1 6.7e+02 1.1 0.0 7.2 8 0 0 8 8 8 0 Bacterial Ig domain TraK PF06586.11 PFH37579.1 - 0.0013 18.5 2.7 3.1e+02 0.9 0.0 7.0 8 0 0 8 8 8 0 TraK protein DUF3861 PF12977.7 PFH37579.1 - 0.0019 18.3 9.6 2.7e+02 1.8 0.0 7.6 8 0 0 8 8 8 0 Domain of Unknown Function with PDB structure (DUF3861) ProRS-C_2 PF09181.10 PFH37579.1 - 0.0079 16.3 11.7 2.6e+02 1.8 0.0 7.6 8 0 0 8 8 8 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 PFH37579.1 - 0.055 13.3 20.0 1.4e+02 2.4 0.1 8.0 8 0 0 8 8 8 0 FlgD Ig-like domain CorA PF01544.18 PFH37579.1 - 2.6 7.3 7.8 4.9e+02 -0.2 0.0 6.1 8 0 0 8 8 8 0 CorA-like Mg2+ transporter protein HMG_box PF00505.19 PFH37580.1 - 4.7e-21 75.0 3.0 4.7e-21 75.0 3.0 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PFH37580.1 - 9.6e-17 61.4 2.5 1.6e-16 60.7 2.5 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 PFH37580.1 - 0.0092 15.9 2.7 0.0092 15.9 2.7 1.8 1 1 1 2 2 2 1 HMG (high mobility group) box 5 KRAB PF01352.27 PFH37580.1 - 0.11 12.2 0.2 0.18 11.5 0.2 1.3 1 0 0 1 1 1 0 KRAB box CKS PF01111.19 PFH37581.1 - 2.3e-22 79.1 0.0 4.4e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF1360 PF07098.11 PFH37581.1 - 0.024 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) LcrG PF07216.12 PFH37581.1 - 0.053 13.4 0.3 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 LcrG protein Ribosomal_S10 PF00338.22 PFH37582.1 - 3.2e-08 33.7 0.0 8.6e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ProRS-C_1 PF09180.11 PFH37583.1 - 9.7e-30 102.6 0.2 2.6e-29 101.2 0.2 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 PFH37583.1 - 1.1e-25 90.6 0.0 2.3e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 PFH37583.1 - 7.1e-23 81.0 0.3 1.3e-22 80.1 0.3 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 PFH37583.1 - 8.1e-19 67.6 0.0 2.5e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain MCM PF00493.23 PFH37584.1 - 2.1e-99 331.2 0.0 3.1e-99 330.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PFH37584.1 - 2e-28 98.8 0.0 3.3e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PFH37584.1 - 1.3e-24 86.4 0.3 1.3e-24 86.4 0.3 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM6_C PF18263.1 PFH37584.1 - 3.7e-08 33.5 4.2 6.3e-08 32.8 0.1 2.8 3 0 0 3 3 3 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 PFH37584.1 - 2.8e-07 31.1 0.3 1.2e-06 29.0 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 PFH37584.1 - 1.1e-05 24.9 0.0 4.4e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PFH37584.1 - 0.0052 16.6 0.0 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PFH37584.1 - 0.025 14.6 0.0 0.084 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 PFH37584.1 - 0.031 14.9 6.0 0.8 10.4 4.4 3.3 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal SPACA9 PF15120.6 PFH37584.1 - 0.059 13.1 0.0 0.4 10.5 0.1 2.1 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 DUF1604 PF07713.13 PFH37585.1 - 1.4e-27 95.3 2.7 6.5e-27 93.2 2.7 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) Kinase-like PF14531.6 PFH37586.1 - 2.3e-52 178.1 0.0 2.9e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH37586.1 - 4.1e-08 32.9 0.0 5e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain PH PF00169.29 PFH37587.1 - 0.001 19.5 0.1 0.0042 17.6 0.0 2.0 2 0 0 2 2 2 1 PH domain FCH PF00611.23 PFH37587.1 - 0.16 12.3 1.2 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Thioredoxin PF00085.20 PFH37588.1 - 1.1e-06 28.5 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 PFH37588.1 - 8.7e-06 24.9 0.1 1e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Phosducin TraF PF13728.6 PFH37588.1 - 0.0065 16.3 1.9 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 F plasmid transfer operon protein DUF4355 PF14265.6 PFH37588.1 - 0.062 13.5 13.2 0.1 12.9 13.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Exonuc_VII_L PF02601.15 PFH37588.1 - 0.18 11.3 6.3 0.21 11.1 6.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Drc1-Sld2 PF11719.8 PFH37588.1 - 0.2 11.1 3.5 0.25 10.9 3.5 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein zf-ZPR1 PF03367.13 PFH37589.1 - 6.9e-96 318.5 0.0 1.3e-48 164.8 0.0 2.4 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Zn-ribbon_8 PF09723.10 PFH37589.1 - 0.0084 16.2 5.4 18 5.6 0.0 4.6 5 0 0 5 5 5 2 Zinc ribbon domain DSBA PF01323.20 PFH37589.1 - 0.015 15.1 0.1 3.2 7.5 0.0 2.5 2 0 0 2 2 2 0 DSBA-like thioredoxin domain HypA PF01155.19 PFH37589.1 - 0.018 15.0 6.0 1.2 9.1 0.3 2.8 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CpXC PF14353.6 PFH37589.1 - 0.17 11.9 7.5 25 4.9 0.1 4.8 3 2 1 4 4 4 0 CpXC protein zf_CopZ PF18423.1 PFH37589.1 - 0.23 11.4 5.2 41 4.2 0.7 3.7 3 0 0 3 3 3 0 Zinc binding domain zinc_ribbon_9 PF14369.6 PFH37589.1 - 0.61 10.4 7.4 19 5.6 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon zf-Di19 PF05605.12 PFH37589.1 - 6.2 7.2 7.3 20 5.5 0.1 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding SAG PF04092.13 PFH37591.1 - 3.8e-32 111.8 0.3 2.8e-15 57.2 0.2 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37592.1 - 1.1e-28 100.6 0.0 4.7e-14 53.3 0.0 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37593.1 - 2.3e-29 102.9 0.0 1.1e-15 58.5 0.0 2.5 2 0 0 2 2 2 2 SRS domain Gpi16 PF04113.14 PFH37595.1 - 1.7e-43 148.9 0.0 1.7e-34 119.2 0.0 3.9 2 1 0 2 2 2 2 Gpi16 subunit, GPI transamidase component RR_TM4-6 PF06459.12 PFH37595.1 - 0.21 11.4 0.2 0.34 10.7 0.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Arrestin_C PF02752.22 PFH37596.1 - 2.4e-14 53.9 1.2 1.2e-13 51.6 0.0 2.5 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PFH37596.1 - 2.5e-12 47.1 1.1 2.8e-11 43.7 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Ribosomal_L19 PF01245.20 PFH37596.1 - 0.0038 17.1 1.6 0.0065 16.4 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L19 GTP_EFTU PF00009.27 PFH37597.1 - 1.1e-48 165.3 0.1 2e-48 164.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 PFH37597.1 - 6.1e-39 132.5 1.3 1.1e-38 131.7 1.3 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 PFH37597.1 - 2.8e-11 43.3 0.0 7e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PFH37597.1 - 7.9e-06 26.2 0.0 2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 PFH37597.1 - 0.0005 19.7 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Ras family EFG_II PF14492.6 PFH37597.1 - 0.0014 18.7 0.0 0.0062 16.6 0.0 2.2 1 1 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 PFH37597.1 - 0.003 17.6 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 PFH37597.1 - 0.046 12.7 0.1 0.12 11.4 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MnmE_helical PF12631.7 PFH37597.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 MnmE helical domain RsgA_GTPase PF03193.16 PFH37597.1 - 0.059 13.3 0.5 0.35 10.8 0.0 2.2 2 1 0 2 2 2 0 RsgA GTPase RF3_C PF16658.5 PFH37597.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain MMR_HSR1_Xtn PF16897.5 PFH37597.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 PFH37597.1 - 0.15 11.8 0.0 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 PFH37597.1 - 0.18 11.2 0.2 0.5 9.8 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family zf-C3HC4_3 PF13920.6 PFH37598.1 - 4.1e-05 23.3 3.6 4.1e-05 23.3 3.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 PFH37598.1 - 0.051 14.2 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PFH37598.1 - 0.079 13.3 0.1 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) 6PGD PF00393.19 PFH37599.1 - 6.1e-113 377.0 0.0 8.4e-113 376.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 PFH37599.1 - 6.6e-43 146.6 0.0 1.1e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SF-assemblin PF06705.11 PFH37600.1 - 1.5e-62 211.1 24.0 1.7e-62 211.0 24.0 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin KIAA1430 PF13879.6 PFH37600.1 - 3.6 8.4 8.4 0.61 10.9 4.5 1.7 2 0 0 2 2 2 0 KIAA1430 homologue Amnionless PF14828.6 PFH37602.1 - 0.0074 15.2 0.8 0.011 14.7 0.8 1.2 1 0 0 1 1 1 1 Amnionless DUF5635 PF18685.1 PFH37602.1 - 0.33 10.9 3.3 0.83 9.6 0.2 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5635) OmpH PF03938.14 PFH37602.1 - 1.1 9.6 14.7 1.8 8.9 9.5 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) BTAD PF03704.17 PFH37603.1 - 0.0063 17.0 3.3 0.015 15.7 3.3 1.6 1 0 0 1 1 1 1 Bacterial transcriptional activator domain GDA1_CD39 PF01150.17 PFH37604.1 - 6.9e-68 229.2 0.0 4.6e-46 157.3 0.0 2.1 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 PFH37604.1 - 0.068 12.6 0.1 0.18 11.2 0.1 1.6 1 1 0 1 1 1 0 Ppx/GppA phosphatase family Peptidase_C2 PF00648.21 PFH37605.1 - 9.2e-06 24.9 0.0 1.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Wbp11 PF09429.10 PFH37605.1 - 2.9 8.3 9.1 0.075 13.4 1.6 2.2 2 0 0 2 2 2 0 WW domain binding protein 11 Fumble PF03630.14 PFH37606.1 - 7.2e-79 265.4 0.0 6e-70 236.0 0.0 3.1 3 0 0 3 3 3 3 Fumble DUF5447 PF17525.2 PFH37607.1 - 0.0012 19.2 2.6 0.0038 17.6 2.6 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5447) tRNA-synt_1e PF01406.19 PFH37612.1 - 5.7e-121 403.5 0.0 1.1e-120 402.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 PFH37612.1 - 3.5e-09 35.9 0.2 0.0014 17.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PFH37612.1 - 0.0052 15.1 0.0 0.014 13.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 PFH37612.1 - 0.065 13.7 0.4 0.24 11.9 0.0 2.3 2 0 0 2 2 2 0 DALR domain TPR_1 PF00515.28 PFH37616.1 - 2.9e-20 71.2 7.1 8.5e-06 25.4 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 PFH37616.1 - 1.2e-19 68.8 13.8 0.0015 18.5 0.0 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 PFH37616.1 - 2e-11 43.2 4.2 0.0027 17.8 0.0 4.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 PFH37616.1 - 2.1e-10 40.1 7.7 0.013 15.2 0.1 4.8 3 2 2 5 5 5 3 TPR repeat TPR_16 PF13432.6 PFH37616.1 - 2.5e-10 40.8 19.5 9.4e-05 23.0 0.6 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 PFH37616.1 - 3.1e-10 40.0 19.1 0.016 15.9 0.0 5.5 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 PFH37616.1 - 7.4e-10 39.0 14.2 0.0017 18.6 0.3 5.0 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 PFH37616.1 - 3e-08 33.7 11.9 6.7e-06 26.2 0.8 3.8 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PFH37616.1 - 1.5e-07 31.8 10.7 1e-05 25.9 0.5 3.8 2 1 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 PFH37616.1 - 4e-07 30.3 11.7 0.12 13.1 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 PFH37616.1 - 8.6e-06 25.8 0.9 0.26 11.7 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 PFH37616.1 - 1.2e-05 24.6 2.1 1.2e-05 24.6 2.1 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PFH37616.1 - 1.4e-05 24.8 11.6 0.47 10.6 0.1 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH37616.1 - 0.00011 22.3 1.7 0.0051 17.0 0.2 3.4 2 1 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Wzy_C_2 PF11846.8 PFH37616.1 - 0.00039 20.4 0.9 0.35 10.8 0.2 2.4 1 1 1 2 2 2 2 Virulence factor membrane-bound polymerase, C-terminal TPR_10 PF13374.6 PFH37616.1 - 0.0074 16.1 9.5 0.16 11.9 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.9 PFH37616.1 - 0.087 12.5 0.0 0.087 12.5 0.0 2.2 4 0 0 4 4 3 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.6 PFH37616.1 - 0.15 12.2 10.3 0.15 12.2 1.1 3.2 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 PFH37616.1 - 0.49 10.5 8.0 8.6 6.5 0.2 3.9 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 PFH37616.1 - 2.4 8.6 13.5 1.6 9.2 1.5 2.9 2 1 0 3 3 3 0 Bacterial transcriptional activator domain zf-Sec23_Sec24 PF04810.15 PFH37617.1 - 0.37 10.9 12.6 0.066 13.3 1.6 3.2 1 1 2 3 3 3 0 Sec23/Sec24 zinc finger zinc_ribbon_5 PF13719.6 PFH37617.1 - 1.2 9.0 9.2 4.3 7.2 2.6 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_12 PF11331.8 PFH37617.1 - 4.4 7.2 10.6 7.8 6.4 0.0 3.5 3 1 0 3 3 3 0 Probable zinc-ribbon domain Ribosomal_S27e PF01667.17 PFH37617.1 - 9.4 6.0 13.4 2.8 7.7 2.4 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 Ribosomal_L18 PF17135.4 PFH37620.1 - 3.6e-86 287.3 3.8 4e-86 287.2 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 PFH37620.1 - 0.00015 22.4 0.7 0.0002 22.1 0.1 1.5 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Peptidase_S32 PF05579.13 PFH37621.1 - 0.043 13.0 0.1 0.065 12.4 0.1 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 DUF3592 PF12158.8 PFH37621.1 - 0.073 13.1 0.3 0.16 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Peptidase_M41 PF01434.18 PFH37622.1 - 2e-54 184.4 0.8 1.2e-53 181.8 0.3 2.2 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 PFH37622.1 - 3.3e-41 140.8 0.0 6.9e-41 139.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PFH37622.1 - 2.6e-10 39.9 1.0 6.2e-10 38.7 1.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 PFH37622.1 - 6.2e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 PFH37622.1 - 0.00023 20.5 0.1 0.00044 19.6 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 PFH37622.1 - 0.0006 20.1 0.7 0.48 10.7 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 PFH37622.1 - 0.0016 18.4 0.5 0.0093 16.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 PFH37622.1 - 0.023 14.5 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 PFH37622.1 - 0.026 14.9 0.1 0.026 14.9 0.1 4.8 4 2 0 5 5 4 0 AAA ATPase domain NACHT PF05729.12 PFH37622.1 - 0.034 14.1 0.5 0.34 10.8 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 PFH37622.1 - 0.034 13.5 0.2 0.085 12.2 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 PFH37622.1 - 0.039 13.9 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 PFH37622.1 - 0.049 13.8 0.1 0.22 11.7 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 PFH37622.1 - 0.093 13.3 0.0 0.37 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PFH37622.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain ATPase PF06745.13 PFH37622.1 - 0.46 9.8 1.5 2.9 7.2 0.0 2.9 4 0 0 4 4 4 0 KaiC AAA_11 PF13086.6 PFH37622.1 - 0.63 9.8 0.0 0.63 9.8 0.0 2.7 4 0 0 4 4 3 0 AAA domain AAA_17 PF13207.6 PFH37622.1 - 0.89 10.0 0.0 0.89 10.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain Hamartin PF04388.12 PFH37622.1 - 2.6 6.6 3.9 5.6 5.5 3.9 1.5 1 0 0 1 1 1 0 Hamartin protein Secretin_N PF03958.17 PFH37622.1 - 9.1 6.8 6.3 2.4 8.6 0.1 3.1 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain UQ_con PF00179.26 PFH37624.1 - 3.6e-39 133.6 0.0 5.3e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAM199X PF15814.5 PFH37624.1 - 0.0021 17.2 0.5 0.0032 16.6 0.5 1.2 1 0 0 1 1 1 1 Protein family FAM199X Prok-E2_B PF14461.6 PFH37624.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B SPC22 PF04573.12 PFH37626.1 - 4.9e-48 162.8 0.0 5.5e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit ACDC PF14733.6 PFH37627.1 - 3.6e-10 40.0 2.5 0.00061 20.1 0.7 2.4 2 0 0 2 2 2 2 AP2-coincident C-terminal CLAG PF03805.13 PFH37628.1 - 5.6e-09 34.2 0.0 0.0004 18.1 0.0 2.7 3 0 0 3 3 3 2 Cytoadherence-linked asexual protein DUF454 PF04304.13 PFH37628.1 - 0.037 14.1 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF454) RLL PF10036.9 PFH37629.1 - 6.7e-47 160.5 0.0 7.7e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein Aminotran_5 PF00266.19 PFH37630.1 - 7.8e-56 189.6 0.0 8.9e-55 186.1 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V AMA-1 PF02430.15 PFH37631.1 - 1.6e-56 192.2 0.6 2.7e-56 191.5 0.6 1.3 1 1 0 1 1 1 1 Apical membrane antigen 1 DUF998 PF06197.13 PFH37631.1 - 0.074 12.6 0.4 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Saf_2TM PF18303.1 PFH37631.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain SWIM PF04434.17 PFH37631.1 - 0.71 9.6 2.8 1.3 8.8 0.2 2.4 2 0 0 2 2 2 0 SWIM zinc finger EF1G PF00647.19 PFH37632.1 - 2.3e-38 130.5 0.1 4.7e-38 129.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 PFH37632.1 - 5.2e-13 49.0 0.0 2e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PFH37632.1 - 2.5e-10 40.6 0.0 4.9e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PFH37632.1 - 2.9e-09 36.8 0.0 7.7e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PFH37632.1 - 3.1e-09 37.1 0.0 7.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PFH37632.1 - 2.5e-07 30.8 0.0 5.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PFH37632.1 - 7.5e-05 22.9 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Trigger_N PF05697.13 PFH37632.1 - 0.016 15.6 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) Ribosomal_60s PF00428.19 PFH37632.1 - 0.32 11.6 10.0 0.61 10.7 10.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Thioredoxin_7 PF13899.6 PFH37633.1 - 1.2e-13 51.0 0.1 2.3e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 PFH37633.1 - 7.1e-09 35.3 0.6 1.3e-08 34.5 0.6 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_2 PF13098.6 PFH37633.1 - 0.0075 16.7 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Miga PF10265.9 PFH37633.1 - 1.1 8.2 3.8 1.6 7.6 3.8 1.3 1 0 0 1 1 1 0 Mitoguardin Apt1 PF10351.9 PFH37633.1 - 1.2 7.9 4.2 1.7 7.4 4.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CENP-H PF05837.12 PFH37635.1 - 0.00087 19.7 3.6 0.0015 18.9 3.6 1.4 1 0 0 1 1 1 1 Centromere protein H (CENP-H) KASH_CCD PF14662.6 PFH37635.1 - 0.012 15.5 0.9 0.018 14.9 0.9 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF2205 PF10224.9 PFH37635.1 - 0.019 14.9 1.1 0.035 14.1 1.1 1.4 1 0 0 1 1 1 0 Short coiled-coil protein NRBF2 PF08961.10 PFH37635.1 - 0.048 13.3 0.6 0.089 12.4 0.6 1.5 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Nup54 PF13874.6 PFH37635.1 - 0.1 12.7 2.9 0.17 12.0 2.9 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Rootletin PF15035.6 PFH37635.1 - 0.11 12.5 3.4 0.18 11.8 3.4 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 PFH37635.1 - 0.13 12.9 0.1 0.2 12.3 0.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA X PF00739.19 PFH37635.1 - 3.9 7.6 11.1 0.05 13.7 3.0 1.9 2 1 0 2 2 2 0 Trans-activation protein X Ribosomal_L37ae PF01780.19 PFH37636.1 - 1.6e-40 137.1 9.9 1.8e-40 136.9 9.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 PFH37636.1 - 0.0041 17.1 2.2 0.0063 16.5 2.2 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Terminase_GpA PF05876.12 PFH37636.1 - 0.014 14.0 1.2 0.014 13.9 1.2 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Elf1 PF05129.13 PFH37636.1 - 0.023 14.7 1.7 0.037 14.1 1.7 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Rep_fac-A_C PF08646.10 PFH37636.1 - 0.057 13.2 0.3 0.068 12.9 0.3 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-H2C2_2 PF13465.6 PFH37636.1 - 0.057 13.9 0.6 0.85 10.2 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain A2L_zn_ribbon PF08792.10 PFH37636.1 - 0.06 13.1 1.6 0.71 9.7 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Di19 PF05605.12 PFH37636.1 - 0.16 12.3 0.8 0.26 11.6 0.1 1.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Histone PF00125.24 PFH37637.1 - 2.3e-17 63.6 0.0 3.3e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 PFH37637.1 - 1e-11 44.4 0.1 2e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 PFH37637.1 - 7.5e-05 22.9 0.0 0.0001 22.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TT1725 PF18324.1 PFH37638.1 - 0.14 12.2 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Hypothetical protein TT1725 TT1725 PF18324.1 PFH37639.1 - 0.12 12.5 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Hypothetical protein TT1725 RXT2_N PF08595.11 PFH37639.1 - 0.18 11.8 0.5 1.6 8.8 0.0 2.5 3 0 0 3 3 3 0 RXT2-like, N-terminal SNase PF00565.17 PFH37640.1 - 4.7e-11 43.1 0.1 1.5e-05 25.5 0.3 2.4 2 0 0 2 2 2 2 Staphylococcal nuclease homologue Syntaxin-6_N PF09177.11 PFH37641.1 - 7.7e-14 52.1 7.9 1.3e-12 48.1 0.5 2.4 2 0 0 2 2 2 2 Syntaxin 6, N-terminal SNARE PF05739.19 PFH37641.1 - 0.0029 17.6 0.9 0.0029 17.6 0.9 2.8 3 0 0 3 3 3 1 SNARE domain DUF812 PF05667.11 PFH37641.1 - 0.04 12.8 14.0 0.057 12.3 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) LMBR1 PF04791.16 PFH37641.1 - 0.15 10.9 5.2 0.17 10.7 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein NPV_P10 PF05531.12 PFH37641.1 - 0.45 11.0 5.7 1.7 9.2 2.3 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein V-SNARE_C PF12352.8 PFH37641.1 - 1.3 9.3 11.2 8.6 6.7 0.2 3.2 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus TMPIT PF07851.13 PFH37641.1 - 2.5 7.3 13.4 0.29 10.3 3.3 2.4 1 1 1 2 2 2 0 TMPIT-like protein 5_3_exonuc PF01367.20 PFH37641.1 - 2.6 8.7 5.7 4.3 8.0 0.1 2.4 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold TFIIA PF03153.13 PFH37641.1 - 2.8 7.9 13.4 3.1 7.7 13.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HeLo PF14479.6 PFH37641.1 - 5.1 6.9 15.2 9.2 6.0 14.1 1.8 1 1 1 2 2 2 0 Prion-inhibition and propagation DUF16 PF01519.16 PFH37641.1 - 5.7 7.5 13.4 1e+02 3.4 13.4 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF2400 PF09674.10 PFH37641.1 - 8 6.4 9.4 30 4.5 7.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) MtN3_slv PF03083.16 PFH37642.1 - 5.3e-41 138.5 6.2 1.7e-20 72.9 0.3 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange LAB_N PF07578.11 PFH37642.1 - 0.00019 21.4 1.0 0.052 13.6 0.2 2.5 2 0 0 2 2 2 2 Lipid A Biosynthesis N-terminal domain tRNA-synt_2b PF00587.25 PFH37643.1 - 9.8e-31 107.1 0.0 1.8e-28 99.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PFH37643.1 - 8.5e-19 67.5 0.2 1.8e-18 66.4 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 PFH37643.1 - 1.8e-10 40.8 0.0 4.9e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 PFH37643.1 - 9.9e-06 25.5 0.0 8.5e-05 22.5 0.0 2.3 1 1 0 1 1 1 1 TGS domain LSM PF01423.22 PFH37645.1 - 4.7e-18 64.6 0.3 7.8e-18 63.9 0.3 1.4 1 1 0 1 1 1 1 LSM domain SNARE PF05739.19 PFH37646.1 - 7.2e-05 22.7 2.9 7.2e-05 22.7 2.9 2.0 2 0 0 2 2 2 1 SNARE domain Sec20 PF03908.13 PFH37646.1 - 0.0083 16.0 0.5 0.016 15.1 0.2 1.7 2 0 0 2 2 2 1 Sec20 Use1 PF09753.9 PFH37646.1 - 0.0096 15.7 0.3 0.1 12.3 0.0 2.0 2 0 0 2 2 2 1 Membrane fusion protein Use1 EMP24_GP25L PF01105.24 PFH37646.1 - 0.032 14.2 0.0 0.051 13.5 0.0 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Syntaxin-6_N PF09177.11 PFH37646.1 - 0.093 13.3 1.5 3 8.5 0.3 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CorA PF01544.18 PFH37646.1 - 0.24 10.7 2.4 0.84 8.9 0.2 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Not3 PF04065.15 PFH37646.1 - 0.34 10.3 1.9 10 5.5 0.0 2.3 2 1 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component GAS PF13851.6 PFH37646.1 - 0.38 10.1 3.7 0.27 10.6 0.2 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 PFH37646.1 - 0.94 9.1 7.0 0.16 11.6 0.5 2.4 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease AAA PF00004.29 PFH37647.1 - 2.2e-41 141.4 0.0 7.4e-41 139.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 PFH37647.1 - 3.1e-19 68.7 0.2 6.3e-19 67.7 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 PFH37647.1 - 3.9e-12 45.8 1.8 5.1e-12 45.4 0.2 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 PFH37647.1 - 1e-06 28.8 0.1 7.2e-06 26.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PFH37647.1 - 3.7e-05 24.2 0.3 0.0046 17.4 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 PFH37647.1 - 7.4e-05 22.5 0.0 0.00019 21.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PFH37647.1 - 0.00046 20.4 0.0 0.0018 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PFH37647.1 - 0.0006 20.1 0.7 0.083 13.2 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 PFH37647.1 - 0.0028 17.8 0.1 0.0088 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 PFH37647.1 - 0.0048 16.3 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 PFH37647.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 PFH37647.1 - 0.014 14.9 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 PFH37647.1 - 0.023 14.4 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 PFH37647.1 - 0.04 13.6 0.1 0.096 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 PFH37647.1 - 0.044 13.1 0.6 0.26 10.6 0.0 2.3 2 0 0 2 2 2 0 KaiC TIP49 PF06068.13 PFH37647.1 - 0.049 12.8 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_18 PF13238.6 PFH37647.1 - 0.055 14.0 0.3 0.53 10.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 PFH37647.1 - 0.084 12.6 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 PFH37647.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 PFH37647.1 - 0.13 11.5 0.6 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin TolA_bind_tri PF16331.5 PFH37647.1 - 0.36 10.9 3.4 1 9.5 0.9 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation RrnaAD PF00398.20 PFH37648.1 - 6.8e-41 140.1 0.0 9.1e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 PFH37648.1 - 0.019 15.7 0.0 0.054 14.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Lentiviral_Tat PF02998.14 PFH37648.1 - 0.054 13.5 2.0 0.18 11.9 2.0 1.9 1 0 0 1 1 1 0 Lentiviral Tat protein Trehalase PF01204.18 PFH37652.1 - 0.35 9.6 1.4 8.6 5.0 0.1 2.1 2 0 0 2 2 2 0 Trehalase Antigen_Bd37 PF11641.8 PFH37654.1 - 0.14 11.7 0.1 0.36 10.3 0.1 1.6 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein CAF1 PF04857.20 PFH37655.1 - 9.8e-50 169.5 0.0 1.4e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Aminotran_5 PF00266.19 PFH37656.1 - 7.3e-30 104.2 0.0 7.7e-29 100.8 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class-V Mito_carr PF00153.27 PFH37657.1 - 3.8e-70 231.9 1.9 4.1e-26 90.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF826 PF05696.11 PFH37658.1 - 0.012 15.7 0.5 0.68 10.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF826) ING PF12998.7 PFH37658.1 - 0.12 12.9 3.7 0.43 11.2 0.8 2.3 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ERO1 PF04137.15 PFH37659.1 - 4.2e-72 243.3 0.0 5.4e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF4006 PF13179.6 PFH37659.1 - 0.052 13.5 0.1 0.096 12.6 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Orf78 PF06024.12 PFH37659.1 - 0.15 12.4 0.2 0.28 11.5 0.2 1.4 1 0 0 1 1 1 0 Orf78 (ac78) MAP17 PF15807.5 PFH37659.1 - 0.17 12.1 0.4 0.28 11.4 0.4 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF747 PF05346.11 PFH37660.1 - 4.6e-26 92.0 0.6 5.3e-26 91.8 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic membrane protein family UCR_UQCRX_QCR9 PF05365.12 PFH37660.1 - 0.23 11.4 0.2 0.23 11.4 0.2 1.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like RPN7 PF10602.9 PFH37661.1 - 1.6e-06 27.9 0.0 0.0046 16.7 0.0 3.4 3 0 0 3 3 3 2 26S proteasome subunit RPN7 PCI PF01399.27 PFH37661.1 - 0.0029 18.1 0.3 0.014 15.9 0.0 2.2 2 0 0 2 2 2 1 PCI domain TPR_14 PF13428.6 PFH37661.1 - 0.31 12.0 13.1 0.54 11.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 PFH37661.1 - 0.35 11.4 5.4 3.2 8.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HEM4 PF02602.15 PFH37663.1 - 2.2e-09 37.0 0.0 0.00011 21.6 0.1 3.7 4 1 0 4 4 4 2 Uroporphyrinogen-III synthase HemD TruD PF01142.18 PFH37665.1 - 9.5e-42 143.3 0.0 6.3e-30 104.3 0.0 3.6 3 2 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) APG6_N PF17675.1 PFH37666.1 - 0.015 15.8 15.2 0.015 15.8 15.2 8.6 1 1 7 8 8 8 0 Apg6 coiled-coil region NYD-SP28_assoc PF14775.6 PFH37666.1 - 0.059 13.5 0.5 0.059 13.5 0.5 7.2 7 1 0 8 8 8 0 Sperm tail C-terminal domain Rrn6 PF10214.9 PFH37667.1 - 2.3 6.6 6.2 0.17 10.3 0.6 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor DEAD PF00270.29 PFH37668.1 - 1.9e-33 115.7 0.0 3.7e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH37668.1 - 2.4e-23 82.6 0.0 5.9e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH37668.1 - 1.1e-08 35.3 0.0 1.9e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 PFH37668.1 - 0.00068 18.5 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 PFH37668.1 - 0.009 16.3 0.2 0.042 14.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PFH37668.1 - 0.12 12.1 0.0 0.12 12.1 0.0 2.3 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 PFH37668.1 - 0.13 12.5 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF763 PF05559.11 PFH37669.1 - 0.077 12.2 0.3 0.13 11.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Bud13 PF09736.9 PFH37671.1 - 1.2e-39 136.0 5.3 1.2e-39 136.0 5.3 3.4 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Myb_DNA-binding PF00249.31 PFH37673.1 - 4.1e-23 81.3 2.8 5.2e-09 36.1 0.1 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PFH37673.1 - 5.4e-19 68.2 0.0 2.8e-06 27.5 0.0 3.8 1 1 2 3 3 3 3 Myb-like DNA-binding domain Phage_Mu_Gam PF07352.12 PFH37674.1 - 0.074 13.0 6.2 0.088 12.7 6.2 1.1 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein GGDEF PF00990.21 PFH37674.1 - 0.075 12.8 1.5 0.17 11.7 1.5 1.5 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF883 PF05957.13 PFH37674.1 - 0.11 13.1 7.2 0.13 12.9 7.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Dak2 PF02734.17 PFH37674.1 - 0.12 12.3 4.4 0.14 12.1 4.4 1.0 1 0 0 1 1 1 0 DAK2 domain LZ3wCH PF18517.1 PFH37674.1 - 0.14 12.3 1.7 0.25 11.5 1.7 1.5 1 0 0 1 1 1 0 Leucine zipper with capping helix domain HisKA_3 PF07730.13 PFH37674.1 - 1.5 9.4 8.2 5.4 7.6 2.7 2.0 1 1 1 2 2 2 0 Histidine kinase PP-binding PF00550.25 PFH37676.1 - 9.2e-15 54.8 0.2 1.2e-14 54.4 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 PFH37676.1 - 0.0026 17.9 0.2 0.0036 17.5 0.2 1.3 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L12_N PF16320.5 PFH37676.1 - 0.0045 16.7 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L7/L12 dimerisation domain DUF1493 PF07377.12 PFH37676.1 - 0.044 14.3 0.1 0.057 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ribosomal_L50 PF10501.9 PFH37676.1 - 0.058 13.6 0.0 0.099 12.8 0.0 1.3 1 1 0 1 1 1 0 Ribosomal subunit 39S LCCL PF03815.19 PFH37677.1 - 3.2e-23 81.7 0.2 9.2e-23 80.2 0.2 1.8 1 0 0 1 1 1 1 LCCL domain F5_F8_type_C PF00754.25 PFH37677.1 - 3.4e-20 72.5 0.5 6.1e-13 49.0 0.0 2.5 2 0 0 2 2 2 2 F5/8 type C domain Ricin_B_lectin PF00652.22 PFH37677.1 - 6.9e-10 39.3 0.2 1.9e-09 37.9 0.2 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain COLFI PF01410.18 PFH37677.1 - 0.00055 19.3 0.5 0.001 18.5 0.1 1.6 2 0 0 2 2 2 1 Fibrillar collagen C-terminal domain DUF1080 PF06439.11 PFH37677.1 - 0.0017 18.5 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1080) PQQ_2 PF13360.6 PFH37677.1 - 0.004 16.8 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain RicinB_lectin_2 PF14200.6 PFH37677.1 - 0.042 14.6 0.1 0.23 12.2 0.1 2.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Wtap PF17098.5 PFH37677.1 - 0.057 13.4 0.4 0.28 11.1 0.2 2.1 2 1 0 2 2 2 0 WTAP/Mum2p family Rxt3 PF08642.10 PFH37677.1 - 0.086 13.6 0.3 0.39 11.5 0.3 1.9 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 TSP_C PF05735.12 PFH37677.1 - 0.11 12.5 0.1 0.73 9.7 0.0 2.1 2 0 0 2 2 2 0 Thrombospondin C-terminal region PCI PF01399.27 PFH37678.1 - 4.8e-10 39.9 0.0 1.5e-09 38.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.6 PFH37678.1 - 0.079 13.8 0.3 0.33 11.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 PFH37678.1 - 0.085 13.0 0.2 0.3 11.3 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 PFH37678.1 - 0.11 13.0 0.1 0.31 11.6 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 PFH37678.1 - 0.11 12.3 1.3 0.18 11.7 0.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1604 PF07713.13 PFH37678.1 - 0.22 11.3 1.1 0.48 10.3 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) UQ_con PF00179.26 PFH37679.1 - 9.4e-19 67.4 0.0 1.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RsmF_methylt_CI PF17126.5 PFH37679.1 - 0.067 13.2 0.0 9 6.4 0.0 2.7 3 0 0 3 3 3 0 RsmF rRNA methyltransferase first C-terminal domain Aminotran_1_2 PF00155.21 PFH37681.1 - 3.3e-40 138.4 0.0 4.6e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1932 PF09130.11 PFH37681.1 - 0.12 12.4 0.3 0.29 11.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) Bromodomain PF00439.25 PFH37682.1 - 3.2e-06 27.1 0.0 4.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain SNRNP27 PF08648.12 PFH37683.1 - 4.9e-26 90.6 2.1 8.4e-26 89.8 2.1 1.4 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Aldedh PF00171.22 PFH37684.1 - 7e-10 38.0 0.1 0.0008 18.0 0.0 3.0 3 0 0 3 3 3 3 Aldehyde dehydrogenase family Unstab_antitox PF09720.10 PFH37684.1 - 0.16 12.1 2.5 0.32 11.1 2.5 1.5 1 0 0 1 1 1 0 Putative addiction module component PPR_2 PF13041.6 PFH37686.1 - 6.7e-41 138.3 0.4 1.1e-11 44.7 0.0 9.4 6 3 5 11 11 11 6 PPR repeat family PPR_3 PF13812.6 PFH37686.1 - 2.4e-23 82.0 0.0 1.9e-08 34.2 0.0 5.9 3 2 4 7 7 7 5 Pentatricopeptide repeat domain PPR PF01535.20 PFH37686.1 - 8e-22 75.9 10.7 0.002 18.3 0.0 10.5 13 0 0 13 13 13 5 PPR repeat PPR_1 PF12854.7 PFH37686.1 - 1.2e-21 76.1 0.0 1.3e-05 24.8 0.0 8.6 8 0 0 8 8 8 5 PPR repeat PPR_long PF17177.4 PFH37686.1 - 3.4e-15 56.0 0.9 2.8e-06 26.9 0.0 5.1 5 1 1 6 6 6 3 Pentacotripeptide-repeat region of PRORP tRNA-synt_1c PF00749.21 PFH37687.1 - 2.4e-101 338.7 0.0 3.1e-101 338.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 PFH37687.1 - 5.1e-37 127.4 0.0 2.4e-36 125.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 PFH37687.1 - 0.00038 20.4 0.1 0.0016 18.5 0.1 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PFH37687.1 - 0.00072 19.7 0.0 0.0026 17.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PFH37687.1 - 0.022 14.9 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Hep_59 PF07052.11 PFH37688.1 - 4.2e-18 66.1 0.2 4.2e-18 66.1 0.2 4.0 3 2 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DUF4937 PF16291.5 PFH37690.1 - 0.053 13.8 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4937 DEAD PF00270.29 PFH37691.1 - 4.3e-40 137.3 0.0 8.1e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH37691.1 - 1.3e-26 93.2 0.0 2.9e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PP_M1 PF03012.14 PFH37692.1 - 0.047 13.2 0.1 0.055 13.0 0.1 1.1 1 0 0 1 1 1 0 Phosphoprotein RNase_P_p30 PF01876.16 PFH37693.1 - 3.1e-17 62.7 0.0 4.1e-07 29.7 0.0 3.3 3 1 0 3 3 3 2 RNase P subunit p30 CTP_transf_1 PF01148.20 PFH37694.1 - 4.4e-42 144.7 0.0 1.6e-41 142.9 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase family Phage_TAC_6 PF09550.10 PFH37695.1 - 0.0049 17.3 3.5 0.032 14.7 0.3 3.3 2 0 0 2 2 2 1 Phage tail assembly chaperone protein, TAC Laminin_II PF06009.12 PFH37696.1 - 0.14 12.2 5.3 1.1 9.2 0.3 2.6 2 0 0 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.9 PFH37696.1 - 0.21 11.9 1.7 1 9.7 0.6 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SHE3 PF17078.5 PFH37696.1 - 0.24 11.1 2.2 0.41 10.3 1.4 1.7 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 ABC_membrane PF00664.23 PFH37697.1 - 8.5e-29 101.1 0.0 1.4e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PFH37697.1 - 2.3e-23 83.2 0.0 8.3e-23 81.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 PFH37697.1 - 0.0013 19.2 4.3 0.0026 18.2 2.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 PFH37697.1 - 0.016 15.3 0.1 0.031 14.4 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain SMC_N PF02463.19 PFH37697.1 - 0.031 13.7 0.7 1 8.8 0.5 2.0 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 PFH37697.1 - 0.032 14.5 0.7 0.29 11.4 0.7 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 PFH37697.1 - 0.1 12.8 0.0 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PFH37697.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RepA1_leader PF08048.12 PFH37697.1 - 3.2 8.1 10.5 0.11 12.7 0.8 3.1 3 0 0 3 3 3 0 Tap RepA1 leader peptide DAO PF01266.24 PFH37698.1 - 6.5e-43 147.7 0.1 9.1e-43 147.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 PFH37698.1 - 3.8e-31 107.6 0.1 8.7e-31 106.4 0.0 1.7 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 PFH37698.1 - 1.9e-10 40.4 0.5 0.00012 21.3 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 PFH37698.1 - 1.2e-07 31.5 0.5 7.5e-06 25.6 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PFH37698.1 - 2e-06 27.3 0.4 0.016 14.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 PFH37698.1 - 0.0055 16.9 0.9 0.04 14.1 0.8 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 PFH37698.1 - 0.025 13.7 0.3 0.11 11.5 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 PFH37698.1 - 0.04 13.1 0.0 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PFH37698.1 - 0.1 11.3 0.2 0.16 10.6 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 PFH37698.1 - 0.15 11.3 0.1 0.28 10.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HMG_box PF00505.19 PFH37699.1 - 4.9e-20 71.7 2.0 7.5e-20 71.1 2.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PFH37699.1 - 1.5e-13 51.1 2.5 2.4e-13 50.4 2.5 1.3 1 0 0 1 1 1 1 HMG-box domain MBOAT PF03062.19 PFH37700.1 - 1.4e-27 97.0 30.7 2.9e-27 95.9 30.7 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 PFH37700.1 - 0.0029 17.8 3.7 0.0029 17.8 3.7 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family SRP-alpha_N PF04086.13 PFH37700.1 - 0.93 9.4 3.2 1.4 8.7 3.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ribosomal_S11 PF00411.19 PFH37701.1 - 7e-48 161.6 1.7 1.1e-47 161.0 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 BKACE PF05853.12 PFH37701.1 - 0.0094 15.3 0.2 0.013 14.8 0.2 1.2 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme DIE2_ALG10 PF04922.12 PFH37702.1 - 2e-57 195.2 0.2 1.1e-24 87.4 0.2 3.5 3 0 0 3 3 3 3 DIE2/ALG10 family FtsJ PF01728.19 PFH37704.1 - 2.4e-60 203.7 0.0 3e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase SPX PF03105.19 PFH37704.1 - 0.023 14.6 0.1 0.024 14.5 0.1 1.2 1 0 0 1 1 1 0 SPX domain COPI_assoc PF08507.10 PFH37705.1 - 0.00054 20.0 7.1 0.00085 19.4 7.1 1.2 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 PFH37705.1 - 0.011 16.0 7.9 0.017 15.5 7.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P WBP-1 PF11669.8 PFH37705.1 - 0.3 11.8 0.2 0.3 11.8 0.2 2.0 2 0 0 2 2 2 0 WW domain-binding protein 1 TMEM72 PF16054.5 PFH37705.1 - 2.4 7.8 9.8 6.7 6.4 9.8 1.6 1 1 0 1 1 1 0 Transmembrane protein family 72 HA2 PF04408.23 PFH37706.1 - 5.8e-23 81.2 0.0 5.8e-23 81.2 0.0 3.2 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PFH37706.1 - 1.3e-17 64.0 0.0 2.8e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PFH37706.1 - 1.9e-13 50.7 0.0 4.7e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PFH37706.1 - 0.00042 20.1 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PFH37706.1 - 0.00058 20.1 0.2 0.0034 17.7 0.2 2.4 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 PFH37706.1 - 0.00092 18.3 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 PFH37706.1 - 0.015 15.0 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PFH37706.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 PFH37706.1 - 0.16 11.6 0.4 3.7 7.1 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF572 PF04502.13 PFH37707.1 - 8.7 5.9 9.3 13 5.3 9.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RRM_1 PF00076.22 PFH37710.1 - 1.6e-13 50.3 0.0 3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH37710.1 - 0.0071 16.4 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif DUF1314 PF07013.11 PFH37710.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Med3 PF11593.8 PFH37711.1 - 6.2 5.9 9.9 9.3 5.3 9.9 1.4 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Ank_2 PF12796.7 PFH37712.1 - 6.5e-19 68.3 0.2 3.4e-08 34.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Bromodomain PF00439.25 PFH37712.1 - 8.5e-19 67.4 0.0 2.6e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 Bromodomain Ank_4 PF13637.6 PFH37712.1 - 1.7e-15 57.2 1.1 1.2e-07 32.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH37712.1 - 3.1e-15 54.7 0.2 0.00023 21.3 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 PFH37712.1 - 5.8e-14 52.0 0.3 6.4e-07 29.5 0.0 3.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PFH37712.1 - 2.2e-12 46.8 0.1 0.0015 18.9 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Med3 PF11593.8 PFH37712.1 - 0.65 9.1 13.6 1.1 8.4 13.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SRP-alpha_N PF04086.13 PFH37712.1 - 0.87 9.5 9.1 1.3 8.8 9.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Baculo_PEP_C PF04513.12 PFH37713.1 - 2.8 8.0 6.2 2.4 8.2 1.0 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HI0933_like PF03486.14 PFH37714.1 - 0.075 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein MRP-L47 PF06984.13 PFH37715.1 - 7e-27 93.4 0.1 7e-27 93.4 0.1 2.3 2 1 1 3 3 3 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) STPPase_N PF16891.5 PFH37715.1 - 0.035 14.6 2.6 0.12 12.9 2.6 1.9 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF2750 PF11042.8 PFH37715.1 - 0.083 13.0 0.2 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2750) DUF4472 PF14739.6 PFH37715.1 - 1.1 10.1 9.0 0.2 12.4 3.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) LCE PF14672.6 PFH37716.1 - 1.3 9.6 6.4 0.75 10.4 2.1 2.2 2 0 0 2 2 2 0 Late cornified envelope Cpn10 PF00166.21 PFH37718.1 - 5.7e-25 87.2 0.2 7.2e-25 86.9 0.2 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit STOP PF05217.12 PFH37719.1 - 0.0023 18.2 5.6 0.023 15.0 0.3 5.1 6 0 0 6 6 6 1 STOP protein GCP_C_terminal PF04130.13 PFH37720.1 - 7e-39 134.1 0.0 1.1e-38 133.5 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PFH37720.1 - 3.3e-28 99.2 0.0 4.7e-26 92.1 0.0 2.2 2 0 0 2 2 2 2 Gamma tubulin complex component N-terminal IR1-M PF12185.8 PFH37720.1 - 0.4 10.6 3.6 1.2 9.2 1.2 2.8 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain Vps26 PF03643.15 PFH37721.1 - 2.7e-107 357.9 3.5 3.1e-107 357.7 3.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 PFH37721.1 - 0.008 16.2 1.2 3.4 7.7 0.0 3.2 3 1 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain UQ_con PF00179.26 PFH37722.1 - 1e-44 151.6 0.0 1.2e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PFH37722.1 - 0.068 13.5 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 PFH37722.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Na_H_Exchanger PF00999.21 PFH37723.1 - 5.8e-46 157.0 34.6 8.3e-46 156.5 34.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Peptidase_C12 PF01088.21 PFH37724.1 - 2.8e-46 157.9 0.0 1.6e-43 149.0 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 La PF05383.17 PFH37725.1 - 1.7e-06 28.0 0.0 0.0021 18.1 0.0 2.4 2 0 0 2 2 2 2 La domain Coilin_N PF15862.5 PFH37725.1 - 5.6e-05 23.0 3.7 0.029 14.2 0.0 4.9 5 2 1 6 6 6 1 Coilin N-terminus PI3K_1B_p101 PF10486.9 PFH37725.1 - 1.8 6.2 5.1 3.5 5.3 5.1 1.6 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop53 PF07767.11 PFH37726.1 - 3.9e-31 108.8 31.3 1.7e-29 103.4 31.3 2.8 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) NAD_binding_2 PF03446.15 PFH37727.1 - 7.6e-48 162.7 0.7 1.1e-47 162.2 0.7 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 PFH37727.1 - 5.1e-36 123.6 0.6 9.6e-36 122.7 0.1 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 PFH37727.1 - 3.3e-09 37.2 0.0 8.8e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 PFH37727.1 - 2.5e-08 33.5 0.0 3.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PFH37727.1 - 2.4e-06 27.6 0.0 3.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 PFH37727.1 - 0.00016 21.6 0.0 0.00039 20.3 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 PFH37727.1 - 0.00044 19.6 1.5 0.00053 19.4 0.4 1.7 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 PFH37727.1 - 0.0026 18.2 0.1 0.017 15.6 0.1 2.2 1 1 1 2 2 2 1 Putative NAD(P)-binding ApbA PF02558.16 PFH37727.1 - 0.0056 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UCH PF00443.29 PFH37728.1 - 1.8e-67 227.5 0.0 2.3e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PFH37728.1 - 3.7e-13 49.8 0.0 5.6e-07 29.5 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 PFH37728.1 - 0.04 14.5 0.0 0.16 12.6 0.0 2.0 2 0 0 2 2 2 0 DUSP domain LCCL PF03815.19 PFH37729.1 - 1.2e-96 317.0 4.1 7.2e-24 83.7 0.1 4.5 4 0 0 4 4 4 4 LCCL domain SRCR PF00530.18 PFH37729.1 - 1.8e-29 102.2 7.7 3.9e-17 62.6 3.1 3.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain PLAT PF01477.23 PFH37729.1 - 1.9e-18 67.1 0.0 5.5e-12 46.3 0.0 3.8 4 0 0 4 4 4 2 PLAT/LH2 domain Laminin_G_3 PF13385.6 PFH37729.1 - 3.3e-16 59.8 0.0 6.8e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Rxt3 PF08642.10 PFH37729.1 - 1e-11 45.7 0.0 0.0084 16.9 0.0 5.2 5 0 0 5 5 5 3 Histone deacetylation protein Rxt3 SRCR_2 PF15494.6 PFH37729.1 - 5.4e-07 30.1 1.9 0.00018 22.0 0.2 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Pentaxin PF00354.17 PFH37729.1 - 0.00017 21.4 0.0 0.0012 18.5 0.0 2.2 2 0 0 2 2 2 1 Pentaxin family Sialidase PF02973.16 PFH37729.1 - 0.00022 20.8 0.0 0.00042 19.9 0.0 1.4 1 0 0 1 1 1 1 Sialidase, N-terminal domain KH_2 PF07650.17 PFH37731.1 - 0.2 11.5 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 KH domain NIF PF03031.18 PFH37732.1 - 5.5e-49 165.9 0.1 6.8e-49 165.6 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ANAPC4_WD40 PF12894.7 PFH37733.1 - 8.6e-13 48.4 0.1 0.00021 21.5 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PFH37733.1 - 3.4e-11 43.5 9.4 0.032 15.1 0.0 7.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 PFH37733.1 - 0.0093 15.0 0.0 0.43 9.5 0.0 2.7 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 PFH37733.1 - 0.01 15.2 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal BBS2_Mid PF14783.6 PFH37733.1 - 0.026 14.6 0.0 2.6 8.1 0.0 2.6 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Utp8 PF10395.9 PFH37733.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Utp8 family YhhN PF07947.14 PFH37734.1 - 0.0017 18.0 1.4 0.0027 17.3 1.4 1.2 1 0 0 1 1 1 1 YhhN family DUF1304 PF06993.12 PFH37734.1 - 0.015 15.3 1.6 1.6 8.8 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) DUF4064 PF13273.6 PFH37734.1 - 0.11 12.8 1.8 9.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3367 PF11847.8 PFH37734.1 - 0.11 10.3 1.9 0.16 9.8 1.5 1.4 1 1 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase DUF872 PF05915.12 PFH37734.1 - 0.14 12.3 0.1 7 6.8 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Baculo_11_kDa PF06143.11 PFH37734.1 - 0.38 10.3 0.0 0.38 10.3 0.0 2.3 3 0 0 3 3 3 0 Baculovirus 11 kDa family Tetraspanin PF00335.20 PFH37734.1 - 0.74 9.5 17.2 6.7 6.3 0.1 2.7 1 1 0 2 2 2 0 Tetraspanin family DUF1772 PF08592.11 PFH37734.1 - 0.79 10.0 4.8 27 5.1 4.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Multi_Drug_Res PF00893.19 PFH37734.1 - 1.1 9.9 5.3 0.19 12.4 1.1 1.7 2 0 0 2 2 2 0 Small Multidrug Resistance protein GPI2 PF06432.11 PFH37734.1 - 4.7 6.6 7.0 4.7 6.6 5.5 1.6 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase SpoU_methylase PF00588.19 PFH37735.1 - 3.7e-17 62.8 0.0 6.6e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 SpoU rRNA Methylase family DUF1681 PF07933.14 PFH37736.1 - 3.1e-48 163.2 0.0 4.1e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Fis1_TPR_C PF14853.6 PFH37737.1 - 2.2e-19 69.3 0.2 6.7e-19 67.7 0.1 1.9 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 PFH37737.1 - 2.1e-08 33.7 0.1 3.7e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 PFH37737.1 - 2.5e-05 24.0 0.4 0.00049 20.0 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 PFH37737.1 - 0.0059 16.7 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PFH37737.1 - 0.063 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PFH37737.1 - 0.078 13.7 0.0 0.53 11.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PFH37737.1 - 0.098 13.2 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 PFH37737.1 - 0.12 13.0 0.0 0.37 11.5 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat B12D PF06522.11 PFH37737.1 - 0.24 11.2 0.3 0.38 10.6 0.3 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Cir_N PF10197.9 PFH37739.1 - 3.8e-11 43.0 11.7 3.8e-11 43.0 11.7 3.3 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Porin_3 PF01459.22 PFH37740.1 - 1.8e-14 53.8 1.9 2.2e-14 53.6 1.9 1.1 1 0 0 1 1 1 1 Eukaryotic porin DUF4316 PF14195.6 PFH37740.1 - 0.015 15.0 0.2 0.033 13.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Rhomboid PF01694.22 PFH37741.1 - 1.6e-26 93.1 13.5 2.6e-26 92.4 13.5 1.4 1 0 0 1 1 1 1 Rhomboid family DUF2101 PF09874.9 PFH37741.1 - 0.25 11.0 1.8 0.4 10.4 0.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2101) DUF3488 PF11992.8 PFH37741.1 - 1.2 8.1 8.4 1.6 7.6 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Fibrinogen_BP PF08017.11 PFH37743.1 - 0.076 11.4 4.3 0.11 11.0 4.3 1.1 1 0 0 1 1 1 0 Fibrinogen binding protein Spt20 PF12090.8 PFH37743.1 - 0.35 10.4 12.3 0.47 10.0 12.3 1.1 1 0 0 1 1 1 0 Spt20 family SLC12 PF03522.15 PFH37743.1 - 1.1 8.2 7.4 1.6 7.7 7.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PA26 PF04636.13 PFH37743.1 - 1.7 7.4 6.0 2.5 6.9 6.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RR_TM4-6 PF06459.12 PFH37743.1 - 2 8.2 10.7 2.6 7.8 10.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_II_R PF09551.10 PFH37743.1 - 9.3 6.7 8.4 16 6.0 8.4 1.3 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) GDPD PF03009.17 PFH37744.1 - 1.8e-16 60.7 0.0 3e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family MFS_1 PF07690.16 PFH37745.1 - 1.5e-08 34.0 16.3 1.5e-08 34.0 16.3 3.4 2 2 0 3 3 3 1 Major Facilitator Superfamily DUF1516 PF07457.11 PFH37745.1 - 0.16 12.2 0.1 0.34 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) CPW_WPC PF09717.10 PFH37747.1 - 4.7e-15 56.3 0.6 7.1e-15 55.7 0.6 1.3 1 0 0 1 1 1 1 Plasmodium falciparum domain of unknown function (CPW_WPC) FlaF PF07309.11 PFH37747.1 - 0.022 14.8 1.4 0.035 14.1 1.4 1.3 1 0 0 1 1 1 0 Flagellar protein FlaF CPW_WPC PF09717.10 PFH37748.1 - 6.3e-10 39.9 1.0 6.3e-10 39.9 1.0 2.1 2 0 0 2 2 2 1 Plasmodium falciparum domain of unknown function (CPW_WPC) ORF11CD3 PF10549.9 PFH37748.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 ORF11CD3 domain Cys_Knot_tox PF17486.2 PFH37748.1 - 1.3 9.3 4.5 3.8 7.8 0.1 2.9 1 1 2 3 3 3 0 Cystine knot toxins MerC PF03203.14 PFH37749.1 - 7.4e-21 74.8 11.8 7.4e-21 74.8 11.8 1.3 2 0 0 2 2 2 1 MerC mercury resistance protein Pkinase PF00069.25 PFH37751.1 - 3e-18 66.1 0.0 2.4e-17 63.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PFH37751.1 - 4.8e-16 58.9 0.0 1.8e-15 57.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH37751.1 - 7e-06 25.5 0.0 2.1e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase UIM PF02809.20 PFH37752.1 - 0.00024 20.8 22.6 0.0015 18.3 4.9 3.7 3 0 0 3 3 3 2 Ubiquitin interaction motif PRORP PF16953.5 PFH37752.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-only RNase P RAP80_UIM PF18282.1 PFH37752.1 - 1.5 8.6 10.6 1.2 9.0 1.8 3.7 2 1 1 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif GAS PF13851.6 PFH37753.1 - 0.013 14.9 42.4 0.06 12.7 12.2 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding RNA_pol_Rpb2_4 PF04566.13 PFH37753.1 - 0.31 11.4 0.8 11 6.4 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 IKKbetaNEMObind PF12179.8 PFH37753.1 - 0.34 11.0 1.7 1.3 9.1 1.7 2.0 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain Baculo_PEP_C PF04513.12 PFH37753.1 - 0.78 9.8 3.9 2.3 8.3 4.0 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec34 PF04136.15 PFH37753.1 - 0.83 9.5 19.5 0.028 14.3 2.0 3.0 2 1 1 3 3 3 0 Sec34-like family Lyase_1 PF00206.20 PFH37754.1 - 1.6e-50 172.3 0.0 2.3e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 PFH37754.1 - 4.5e-43 146.0 0.6 8.4e-43 145.1 0.1 1.7 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal GTP_cyclohydro2 PF00925.20 PFH37754.1 - 0.064 12.8 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 GTP cyclohydrolase II Myosin_head PF00063.21 PFH37755.1 - 1.7e-180 601.6 0.1 2e-180 601.4 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 PFH37755.1 - 0.0038 17.6 0.0 0.018 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 PFH37755.1 - 0.016 14.5 0.1 0.034 13.4 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 PFH37755.1 - 0.047 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PFH37755.1 - 0.066 13.5 0.1 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PFH37755.1 - 0.083 13.4 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 PFH37755.1 - 0.16 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 PFH37755.1 - 0.16 11.0 0.1 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CS PF04969.16 PFH37756.1 - 0.00027 21.9 0.0 0.00051 21.0 0.0 1.5 1 1 0 1 1 1 1 CS domain TPR_19 PF14559.6 PFH37757.1 - 2.2e-07 31.3 7.8 0.00059 20.3 0.0 5.0 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 PFH37757.1 - 4e-07 29.7 0.3 0.014 15.6 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 PFH37757.1 - 4.9e-05 23.1 4.5 0.0052 16.8 0.0 4.7 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 PFH37757.1 - 6.7e-05 23.4 11.7 0.048 14.5 0.1 6.2 4 1 2 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 PFH37757.1 - 0.00091 19.4 0.0 8.5 7.0 0.0 4.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 PFH37757.1 - 0.0013 19.0 5.5 0.21 11.9 0.3 4.6 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 PFH37757.1 - 0.0021 17.8 0.1 0.019 14.8 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 PFH37757.1 - 0.0046 16.6 0.2 0.013 15.2 0.2 1.8 1 0 0 1 1 1 1 TPR repeat TPR_MalT PF17874.1 PFH37757.1 - 0.0053 16.2 4.8 0.0066 15.9 1.0 2.4 2 0 0 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 PFH37757.1 - 0.0053 16.6 1.4 0.56 10.1 0.1 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 PFH37757.1 - 0.11 13.2 8.8 9.4 7.2 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3043 PF11241.8 PFH37757.1 - 0.15 12.1 0.1 0.41 10.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) TPR_20 PF14561.6 PFH37757.1 - 0.5 10.7 4.2 2.6 8.4 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PFH37757.1 - 0.78 10.5 0.0 0.78 10.5 0.0 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat SAG PF04092.13 PFH37758.1 - 1.4e-43 148.9 13.6 2.8e-24 86.4 0.3 2.7 3 0 0 3 3 3 2 SRS domain SAG PF04092.13 PFH37759.1 - 1.6e-46 158.4 17.1 3.1e-24 86.2 0.4 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37760.1 - 2.2e-49 167.6 15.1 1.6e-24 87.2 3.4 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37761.1 - 4.7e-10 40.4 0.3 1.2e-09 39.0 0.2 1.7 2 0 0 2 2 2 1 SRS domain SAG PF04092.13 PFH37762.1 - 1e-46 158.9 15.1 1.8e-23 83.8 3.2 2.0 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37763.1 - 2.6e-49 167.4 23.5 7.5e-25 88.2 4.5 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37764.1 - 1.6e-43 148.7 15.5 3e-22 79.8 3.0 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37765.1 - 9.7e-44 149.3 15.6 1.5e-21 77.6 0.2 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37766.1 - 3.1e-46 157.4 16.1 1.3e-24 87.5 2.7 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37767.1 - 6.4e-41 140.2 14.8 2.7e-21 76.7 0.3 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.13 PFH37768.1 - 4.8e-45 153.6 14.4 8.4e-26 91.3 1.1 2.1 2 0 0 2 2 2 2 SRS domain DUF5067 PF16729.5 PFH37768.1 - 0.029 14.3 0.6 0.05 13.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5067) Phyto-Amp PF15438.6 PFH37768.1 - 0.23 11.3 2.1 32 4.3 0.0 3.1 1 1 1 3 3 3 0 Antigenic membrane protein of phytoplasma SNF2_N PF00176.23 PFH37769.1 - 1.3e-61 208.3 0.0 2.3e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PFH37769.1 - 3.2e-14 53.2 0.0 9e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH37769.1 - 0.00023 21.2 0.0 0.00061 19.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Citrate_synt PF00285.21 PFH37770.1 - 1.8e-107 359.5 0.1 2.2e-107 359.2 0.1 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Ribosomal_L27 PF01016.19 PFH37772.1 - 1.7e-08 34.4 0.2 7.6e-08 32.3 0.2 2.0 2 1 0 2 2 2 1 Ribosomal L27 protein THDPS_N_2 PF14805.6 PFH37773.1 - 0.065 13.5 0.2 0.59 10.4 0.0 2.5 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal 14-3-3 PF00244.20 PFH37774.1 - 3.7e-101 337.3 11.3 4.3e-101 337.0 11.3 1.0 1 0 0 1 1 1 1 14-3-3 protein MKT1_N PF12247.8 PFH37774.1 - 0.03 14.7 1.8 0.089 13.2 0.3 2.6 2 2 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication Peptidase_C98 PF15499.6 PFH37774.1 - 0.035 13.6 0.9 0.071 12.6 0.7 1.7 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase TPR_12 PF13424.6 PFH37774.1 - 0.086 13.1 2.1 0.19 12.1 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat NUC PF18510.1 PFH37774.1 - 0.11 13.0 1.9 0.22 11.9 1.8 1.7 1 1 0 1 1 1 0 Nuclease domain DUF3106 PF11304.8 PFH37774.1 - 5.3 7.6 10.5 92 3.6 6.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) zf-C3HC PF07967.13 PFH37775.1 - 2e-05 24.6 0.9 6.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.10 PFH37775.1 - 0.0039 17.3 0.4 14 5.9 0.1 4.0 4 0 0 4 4 4 2 Rsm1-like TFIID_30kDa PF03540.13 PFH37775.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Pkinase PF00069.25 PFH37777.1 - 8.4e-57 192.5 0.1 1.2e-54 185.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH37777.1 - 2.9e-16 59.6 0.0 5.7e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 PFH37777.1 - 1.4e-06 28.4 0.0 8.6e-05 22.6 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PFH37777.1 - 0.0096 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SR-25 PF10500.9 PFH37777.1 - 0.034 13.7 0.1 0.034 13.7 0.1 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase_fungal PF17667.1 PFH37777.1 - 0.04 12.7 0.4 0.076 11.8 0.4 1.5 1 1 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 PFH37777.1 - 0.22 11.1 0.1 0.37 10.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase M_domain PF12938.7 PFH37777.1 - 1.2 8.9 5.1 2.3 7.9 5.1 1.3 1 0 0 1 1 1 0 M domain of GW182 PC_rep PF01851.22 PFH37778.1 - 5.5e-28 96.0 35.1 1.6e-05 25.1 0.1 9.7 10 0 0 10 10 10 6 Proteasome/cyclosome repeat RPN2_C PF18004.1 PFH37778.1 - 5.7e-22 78.4 14.6 5.7e-22 78.4 14.6 4.3 2 1 1 3 3 3 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 PFH37778.1 - 1.6e-14 54.1 9.3 2.4e-11 43.9 0.0 4.1 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 PFH37778.1 - 3.2e-06 27.5 1.1 0.0033 17.9 0.1 4.4 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 PFH37778.1 - 2.8e-05 24.0 4.4 5.7 7.5 0.1 5.8 6 1 1 7 7 7 3 HEAT repeat HEAT_PBS PF03130.16 PFH37778.1 - 0.62 10.9 7.3 26 5.9 0.1 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Folate_carrier PF01770.18 PFH37778.1 - 8.7 5.0 7.1 0.36 9.5 0.0 2.0 2 0 0 2 2 2 0 Reduced folate carrier Ribosomal_L13e PF01294.18 PFH37779.1 - 4.5e-73 244.9 3.2 5.4e-73 244.7 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S9 PF00380.19 PFH37780.1 - 1.8e-32 112.4 0.1 2.1e-32 112.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Dynein_light PF01221.18 PFH37781.1 - 2.4e-26 91.9 0.9 2.7e-26 91.7 0.9 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Ribosomal_L33 PF00471.20 PFH37782.1 - 1.8e-18 66.7 0.6 2.8e-18 66.1 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L33 Beach PF02138.18 PFH37783.1 - 1.6e-72 244.2 0.0 4.2e-46 157.5 0.0 2.4 2 1 0 2 2 2 2 Beige/BEACH domain WD40 PF00400.32 PFH37783.1 - 2.6e-05 24.9 8.2 0.00071 20.3 0.6 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat CBM_20 PF00686.19 PFH37784.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Starch binding domain DUF5408 PF17402.2 PFH37785.1 - 0.15 11.9 1.4 0.2 11.5 0.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5408) zf-CCCH_4 PF18044.1 PFH37786.1 - 0.012 15.4 4.3 3.4 7.6 0.0 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger Torus PF16131.5 PFH37786.1 - 0.19 12.4 1.2 2.4 8.9 0.3 2.7 2 0 0 2 2 2 0 Torus domain zf_CCCH_4 PF18345.1 PFH37786.1 - 0.35 11.0 7.4 0.14 12.2 0.8 2.8 2 0 0 2 2 2 0 Zinc finger domain LUC7 PF03194.15 PFH37787.1 - 3.5e-53 180.9 0.6 3.5e-53 180.9 0.6 2.1 2 1 0 2 2 2 1 LUC7 N_terminus ABC_tran_CTD PF16326.5 PFH37787.1 - 2 8.7 5.1 2.1 8.7 3.3 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain Neur_chan_memb PF02932.16 PFH37787.1 - 2.7 8.0 12.5 0.27 11.3 7.9 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ApoO PF09769.9 PFH37788.1 - 2.9 7.9 5.7 93 3.0 5.7 2.7 1 1 0 1 1 1 0 Apolipoprotein O RmuC PF02646.16 PFH37788.1 - 6.7 5.8 23.1 0.18 10.9 0.9 2.9 2 1 1 3 3 3 0 RmuC family Asp PF00026.23 PFH37789.1 - 8.6e-69 232.3 0.0 1.1e-68 232.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 PFH37789.1 - 1.1e-11 45.2 0.0 1.2e-06 28.8 0.0 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Phage_GPD PF05954.11 PFH37789.1 - 0.012 15.0 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Trypsin_2 PF13365.6 PFH37792.1 - 6.5e-23 82.3 0.2 1.5e-22 81.1 0.2 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_3 PF17815.1 PFH37792.1 - 9.3e-19 67.7 0.0 2.3e-09 37.3 0.0 2.3 1 1 1 2 2 2 2 PDZ domain Trypsin PF00089.26 PFH37792.1 - 1.8e-10 41.0 0.0 3.6e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 PFH37792.1 - 0.00074 19.3 0.6 0.0025 17.6 0.1 2.2 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 PFH37792.1 - 0.017 15.4 0.0 0.049 14.0 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 PFH37792.1 - 0.064 13.6 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 PDZ domain PDZ_3 PF17815.1 PFH37793.1 - 6.9e-31 107.1 0.0 1.2e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 PFH37793.1 - 1.7e-21 77.7 1.3 3.9e-21 76.5 1.3 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PFH37793.1 - 9.3e-14 51.8 0.0 1.4e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 PFH37793.1 - 1.3e-05 24.9 1.5 0.0036 17.1 0.2 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 PFH37793.1 - 0.0037 17.5 0.3 0.013 15.8 0.1 2.1 2 0 0 2 2 2 1 PDZ domain NAD_binding_1 PF00175.21 PFH37794.1 - 7.5e-27 94.1 0.0 1.2e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PFH37794.1 - 3.1e-23 82.0 0.0 9.4e-21 74.0 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 PFH37794.1 - 0.0025 17.9 0.0 0.0072 16.5 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 PFH37794.1 - 0.0029 17.8 0.0 0.0057 16.9 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Phage_TAC_6 PF09550.10 PFH37794.1 - 0.75 10.3 0.1 0.75 10.3 0.1 2.4 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC CAF1 PF04857.20 PFH37795.1 - 0.98 8.5 5.0 2.3 7.3 5.0 1.7 1 0 0 1 1 1 0 CAF1 family ribonuclease TAF6_C PF07571.13 PFH37797.1 - 0.1 12.9 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Arf PF00025.21 PFH37799.1 - 3.2e-72 241.6 0.0 3.6e-72 241.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PFH37799.1 - 9.4e-14 51.7 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PFH37799.1 - 1.1e-11 44.6 0.0 1.2e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 PFH37799.1 - 5.6e-11 42.2 0.1 3.7e-07 29.6 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 PFH37799.1 - 5.5e-10 39.0 0.0 6.9e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PFH37799.1 - 1.2e-09 37.9 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PFH37799.1 - 4e-06 26.9 0.0 7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 PFH37799.1 - 0.015 14.3 0.1 0.18 10.8 0.0 2.4 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 PFH37799.1 - 0.019 14.5 0.5 0.064 12.8 0.5 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 PFH37799.1 - 0.081 13.5 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain SPRY PF00622.28 PFH37800.1 - 0.00026 21.1 0.2 0.012 15.8 0.1 2.9 3 0 0 3 3 3 1 SPRY domain Peptidase_C50 PF03568.17 PFH37802.1 - 1.4e-26 93.6 0.1 2.5e-12 46.6 0.0 4.0 4 0 0 4 4 4 3 Peptidase family C50 DUF3024 PF11225.8 PFH37802.1 - 0.093 13.0 0.2 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) LRR_6 PF13516.6 PFH37803.1 - 4.2e-07 29.5 14.1 0.00084 19.2 0.8 5.2 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 PFH37803.1 - 0.00061 20.0 3.4 4.7 8.1 0.0 4.8 4 0 0 4 4 4 1 Leucine Rich Repeat Frataxin_Cyay PF01491.16 PFH37803.1 - 0.00089 19.3 0.0 0.41 10.7 0.0 2.8 2 0 0 2 2 2 2 Frataxin-like domain LRR_4 PF12799.7 PFH37803.1 - 0.0038 17.6 9.2 0.045 14.2 3.7 3.3 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) tRNA-synt_1c PF00749.21 PFH37803.1 - 9.1 5.1 10.7 0.28 10.1 4.4 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain FHA PF00498.26 PFH37804.1 - 3.9e-09 36.7 0.0 6.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PFH37804.1 - 0.0068 16.7 0.1 0.61 10.4 0.0 2.6 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain PARG_cat PF05028.14 PFH37805.1 - 4.8e-53 180.6 0.0 2.5e-23 82.9 0.0 4.1 3 1 0 3 3 3 3 Poly (ADP-ribose) glycohydrolase (PARG) SET PF00856.28 PFH37806.1 - 3e-08 34.3 0.0 4.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-rbx1 PF12678.7 PFH37807.1 - 1.8e-08 34.5 2.3 1.8e-08 34.5 2.3 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 PFH37807.1 - 1e-05 25.8 4.7 1e-05 25.8 4.7 2.6 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 PFH37807.1 - 0.00019 21.5 0.2 0.00019 21.5 0.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 PFH37807.1 - 0.0012 18.7 1.6 0.0012 18.7 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH37807.1 - 0.0063 16.5 2.1 0.024 14.6 2.1 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PFH37807.1 - 0.011 15.6 5.8 0.011 15.6 5.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH37807.1 - 0.018 15.0 1.9 0.054 13.5 1.9 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.25 PFH37808.1 - 8.6e-14 51.5 0.0 2.4e-10 40.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 PFH37808.1 - 0.00028 20.3 0.0 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 PFH37808.1 - 0.0035 16.7 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH37808.1 - 0.0059 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PFH37808.1 - 0.017 15.0 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 PFH37808.1 - 0.24 11.0 0.0 0.41 10.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 PFH37809.1 - 2.8e-11 43.3 0.0 4.8e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 PFH37809.1 - 2.2e-10 40.4 0.0 3.6e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PFH37809.1 - 0.0022 17.4 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 PFH37809.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 PFH37810.1 - 1.8e-08 34.1 0.0 2.2e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 PFH37810.1 - 1.3e-05 24.6 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PFH37810.1 - 0.014 15.3 0.1 0.014 15.3 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 PFH37810.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase T-box_assoc PF16176.5 PFH37810.1 - 0.93 9.5 5.4 0.33 11.0 1.5 2.2 3 0 0 3 3 3 0 T-box transcription factor-associated eIF-1a PF01176.19 PFH37811.1 - 1.3e-22 79.4 0.1 1.9e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ctr PF04145.15 PFH37812.1 - 1.6e-23 84.0 3.6 3.2e-23 83.0 3.6 1.5 1 0 0 1 1 1 1 Ctr copper transporter family TPR_9 PF13371.6 PFH37813.1 - 2e-09 37.4 3.3 9.2e-09 35.3 3.3 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 PFH37813.1 - 9.4e-07 28.5 7.9 0.0044 17.0 1.3 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 PFH37813.1 - 1.3e-06 28.0 6.5 0.0046 16.7 0.6 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 PFH37813.1 - 1.3e-05 24.8 9.3 0.00035 20.2 1.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 PFH37813.1 - 0.0021 18.1 1.9 0.049 13.9 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Ribosomal_L27e PF01777.18 PFH37814.1 - 1e-27 96.3 6.7 1.3e-27 95.9 6.7 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 PFH37814.1 - 0.0018 18.2 4.7 0.0018 18.2 4.7 1.9 2 0 0 2 2 2 1 KOW motif Rgp1 PF08737.10 PFH37815.1 - 1.4e-11 44.2 0.3 4.4e-06 26.1 0.1 3.1 3 0 0 3 3 3 3 Rgp1 Auxin_repressed PF05564.12 PFH37815.1 - 0.25 12.0 0.0 0.25 12.0 0.0 2.7 4 0 0 4 4 4 0 Dormancy/auxin associated protein Ribosomal_L18A PF01775.17 PFH37816.1 - 5.2e-51 171.8 0.3 6.5e-51 171.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A WD40 PF00400.32 PFH37818.1 - 1.5e-08 35.1 5.3 0.015 16.2 0.0 5.5 5 1 0 5 5 5 2 WD domain, G-beta repeat COX4 PF02936.14 PFH37819.1 - 0.0054 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DPM2 PF07297.12 PFH37819.1 - 0.039 14.3 0.2 0.066 13.5 0.2 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) RRM_1 PF00076.22 PFH37820.1 - 4.3e-41 138.6 0.0 1.5e-19 69.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PFH37820.1 - 1.7e-05 24.8 0.0 0.24 11.5 0.1 2.3 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 PFH37820.1 - 0.00056 19.9 0.0 1.4 9.0 0.0 2.4 2 1 0 2 2 2 2 Limkain b1 Nup35_RRM_2 PF14605.6 PFH37820.1 - 0.02 14.9 0.0 8.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF3343 PF11823.8 PFH37820.1 - 0.056 12.9 0.0 14 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) ATP-grasp_2 PF08442.10 PFH37820.1 - 0.12 11.9 0.0 2 8.0 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain RRM_5 PF13893.6 PFH37820.1 - 0.12 12.0 0.0 7.6 6.2 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PFH37820.1 - 0.13 12.4 0.0 16 5.7 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif GRP PF07172.11 PFH37820.1 - 4.7 8.0 61.9 0.078 13.7 23.6 2.5 2 0 0 2 2 2 0 Glycine rich protein family DUF423 PF04241.15 PFH37823.1 - 3.4 7.9 8.3 1.7 8.9 4.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF423) ERAP1_C PF11838.8 PFH37824.1 - 1.8e-06 27.8 1.8 0.00079 19.1 0.2 2.8 2 1 1 3 3 3 2 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 PFH37824.1 - 2e-05 24.9 0.0 3.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 PFH37824.1 - 0.00013 21.6 0.0 0.0018 17.9 0.0 2.5 3 0 0 3 3 3 1 Peptidase family M1 domain Tau95_N PF17682.1 PFH37824.1 - 0.0053 17.0 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Tau95 Triple barrel domain LNP1 PF15419.6 PFH37824.1 - 2.1 8.5 10.0 7.8 6.7 0.7 3.2 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 DUF3597 PF12200.8 PFH37825.1 - 2.6 8.6 7.4 15 6.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) FXR_C3 PF16097.5 PFH37827.1 - 0.066 13.9 4.9 0.043 14.5 1.2 2.8 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 Pkinase PF00069.25 PFH37828.1 - 7e-50 169.8 0.0 4.2e-25 88.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH37828.1 - 2.6e-20 72.8 0.0 8.3e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PFH37828.1 - 0.0029 17.0 0.2 4.6 6.5 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 PFH37828.1 - 0.074 12.4 0.8 0.21 10.9 0.8 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.6 PFH37829.1 - 4.8e-07 29.3 14.1 5.8 7.2 0.0 8.1 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 PFH37829.1 - 1.5e-06 28.4 8.3 2.8 8.5 0.1 6.5 5 1 0 6 6 6 3 Leucine Rich repeats (2 copies) F-box PF00646.33 PFH37829.1 - 4.6e-05 23.2 3.1 0.00015 21.5 0.1 3.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PFH37829.1 - 0.00011 22.0 0.2 0.00029 20.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 PFH37829.1 - 0.2 11.4 6.7 17 5.2 0.1 4.6 4 1 1 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 PFH37829.1 - 1.4 9.8 4.1 91 4.2 1.5 4.1 2 0 0 2 2 2 0 Leucine Rich Repeat Pro_isomerase PF00160.21 PFH37830.1 - 9.4e-28 97.5 0.0 1.2e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MMR_HSR1 PF01926.23 PFH37831.1 - 1.1e-14 54.4 0.0 2.2e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PFH37831.1 - 0.00067 19.6 0.0 0.02 14.8 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 PFH37831.1 - 0.0057 16.2 0.4 2.9 7.4 0.0 3.1 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 PFH37831.1 - 0.036 14.1 1.6 0.16 12.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 PFH37831.1 - 0.093 12.3 0.0 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.27 PFH37831.1 - 0.13 12.8 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Hydrolase_4 PF12146.8 PFH37832.1 - 4.1e-12 45.9 0.2 4.9e-06 26.0 0.2 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PFH37832.1 - 1.5e-10 41.2 0.2 0.00016 21.4 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PFH37832.1 - 5.7e-05 22.7 0.0 0.001 18.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 PFH37832.1 - 6.9e-05 22.7 0.2 0.00031 20.6 0.2 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF818 PF05677.12 PFH37832.1 - 7.8e-05 21.8 0.1 0.00011 21.3 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 PFH37832.1 - 0.00077 19.2 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.14 PFH37832.1 - 0.0023 17.3 0.2 0.16 11.3 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase Peptidase_S15 PF02129.18 PFH37832.1 - 0.0087 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 PFH37832.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Asp2 PF16929.5 PFH37832.1 - 0.04 12.9 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Robl_LC7 PF03259.17 PFH37833.1 - 3.7e-26 90.7 0.0 4.2e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 PFH37833.1 - 7.3e-05 22.6 0.0 8.4e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 MAPKK1_Int PF08923.10 PFH37833.1 - 0.031 14.1 0.1 0.057 13.2 0.1 1.7 1 1 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting UPF0176_N PF17773.1 PFH37833.1 - 0.17 12.3 0.0 0.2 12.0 0.0 1.1 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain Drf_FH1 PF06346.12 PFH37834.1 - 0.27 10.9 8.8 0.62 9.8 8.8 1.6 1 0 0 1 1 1 0 Formin Homology Region 1 CREPT PF16566.5 PFH37834.1 - 7.3 6.8 11.6 48 4.1 0.1 4.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour PX PF00787.24 PFH37835.1 - 5.1e-08 32.9 0.0 0.0024 17.8 0.0 2.5 2 0 0 2 2 2 2 PX domain SRF-TF PF00319.18 PFH37835.1 - 0.11 11.9 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Dymeclin PF09742.9 PFH37836.1 - 7.7e-35 120.4 0.0 1.5e-31 109.6 0.0 2.4 2 0 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 PFH37836.1 - 0.21 9.7 0.0 0.53 8.3 0.0 1.6 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GcpE PF04551.14 PFH37838.1 - 7.1e-06 25.3 0.0 1e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 GcpE protein GcpE PF04551.14 PFH37839.1 - 1.5e-124 415.6 0.0 9.8e-80 268.3 0.0 2.1 2 0 0 2 2 2 2 GcpE protein Myb_DNA-binding PF00249.31 PFH37840.1 - 1.9e-09 37.6 0.1 4.4e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 PFH37840.1 - 2.6e-09 36.7 3.9 4.6e-09 35.9 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 PFH37840.1 - 4.7e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 PFH37840.1 - 0.07 13.4 3.3 0.14 12.5 3.3 1.4 1 0 0 1 1 1 0 C1 domain CCT PF06203.14 PFH37840.1 - 0.16 12.0 2.2 0.44 10.6 2.2 1.8 1 0 0 1 1 1 0 CCT motif WD40 PF00400.32 PFH37841.1 - 1e-10 42.0 9.6 1.2e-05 26.0 0.3 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH37841.1 - 0.0012 19.1 0.0 6.2 7.2 0.0 3.6 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Lipase_3 PF01764.25 PFH37842.1 - 9.6e-09 35.2 0.0 2.8e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 PFH37842.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TLD PF07534.16 PFH37843.1 - 1.4e-30 106.3 0.2 2.2e-30 105.7 0.2 1.3 1 0 0 1 1 1 1 TLD GTP_EFTU PF00009.27 PFH37844.1 - 2.2e-58 197.0 0.1 3e-58 196.6 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PFH37844.1 - 1e-23 83.7 0.0 4.3e-23 81.8 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PFH37844.1 - 2e-16 60.1 0.5 3.9e-16 59.2 0.5 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PFH37844.1 - 0.00012 22.1 0.0 0.00026 21.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PFH37844.1 - 0.031 14.2 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 PFH37844.1 - 0.044 13.4 0.1 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ubiquitin PF00240.23 PFH37846.1 - 8.3e-08 31.9 0.0 3.8e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 PFH37846.1 - 0.0014 18.5 0.0 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 PFH37846.1 - 0.079 13.3 0.0 0.14 12.5 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-like domain SP_C-Propep PF08999.10 PFH37846.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide GABP-alpha PF11620.8 PFH37846.1 - 0.19 11.9 0.1 0.29 11.4 0.1 1.3 1 0 0 1 1 1 0 GA-binding protein alpha chain Kelch_1 PF01344.25 PFH37847.1 - 1.2e-52 175.3 5.0 6.8e-10 38.4 0.0 6.7 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 PFH37847.1 - 1.1e-33 114.4 0.0 1.2e-06 28.6 0.0 6.2 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 PFH37847.1 - 2.4e-21 74.8 0.4 0.00087 19.2 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 PFH37847.1 - 1.1e-20 73.3 0.0 6.1e-05 22.9 0.0 5.7 5 1 1 6 6 6 5 Galactose oxidase, central domain BTB_2 PF02214.22 PFH37847.1 - 1.3e-15 57.5 0.0 2.4e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 PFH37847.1 - 1.9e-15 56.7 1.7 0.12 12.7 0.0 6.9 6 2 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PFH37847.1 - 1.3e-10 41.1 0.0 0.024 14.6 0.0 5.1 5 0 0 5 5 5 3 Kelch motif TerB_C PF15615.6 PFH37847.1 - 0.034 14.5 1.3 0.056 13.7 1.3 1.3 1 0 0 1 1 1 0 TerB-C domain Abhydrolase_6 PF12697.7 PFH37849.1 - 1.5e-28 101.0 0.3 2.5e-28 100.2 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PFH37849.1 - 3.8e-08 32.9 0.8 0.0026 17.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PFH37849.1 - 1.8e-07 31.1 0.0 0.0013 18.5 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.13 PFH37849.1 - 0.0054 16.5 0.1 0.0089 15.8 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein LIG3_BRCT PF16759.5 PFH37849.1 - 0.05 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Thioesterase PF00975.20 PFH37849.1 - 0.076 13.1 0.1 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_2 PF02230.16 PFH37849.1 - 0.079 12.8 0.3 8 6.2 0.1 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 PFH37849.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 PFH37849.1 - 0.18 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family IQ PF00612.27 PFH37851.1 - 4.6e-13 47.7 15.2 0.0096 15.6 1.4 4.7 4 0 0 4 4 4 4 IQ calmodulin-binding motif AMPK1_CBM PF16561.5 PFH37851.1 - 6.3e-13 48.7 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase TPR_12 PF13424.6 PFH37853.1 - 1.1e-09 38.4 0.7 2.5e-06 27.7 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 PFH37853.1 - 1.9e-09 36.8 1.5 4e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_1 PF00515.28 PFH37853.1 - 6.8e-08 32.0 0.2 0.0059 16.4 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PFH37853.1 - 2e-07 30.6 1.3 0.01 15.9 0.9 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 PFH37853.1 - 0.00047 19.9 0.4 0.49 10.3 1.9 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 PFH37853.1 - 0.00073 20.1 1.9 7.1 7.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PFH37853.1 - 0.0083 15.8 0.0 0.99 9.1 0.1 2.8 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 PFH37853.1 - 0.013 15.5 0.6 11 6.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat FlxA PF14282.6 PFH37853.1 - 0.085 12.9 0.2 0.085 12.9 0.2 3.3 4 0 0 4 4 4 0 FlxA-like protein RAP1 PF07218.11 PFH37853.1 - 6.9 4.8 7.0 15 3.7 7.0 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Brr6_like_C_C PF10104.9 PFH37855.1 - 3e-30 104.7 0.0 4.4e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain KH_8 PF17903.1 PFH37856.1 - 2.4e-32 110.9 0.8 3.8e-32 110.2 0.0 1.8 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 PFH37856.1 - 2.9e-05 23.8 0.0 8e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 KH domain Kinase-like PF14531.6 PFH37858.1 - 2.6e-19 69.6 0.0 3.8e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH37858.1 - 5.1e-19 68.7 0.0 7.7e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH37858.1 - 5e-06 26.0 0.0 3.6e-05 23.2 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 PFH37858.1 - 0.0041 17.1 0.1 0.011 15.6 0.1 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PFH37858.1 - 0.016 14.6 0.0 0.058 12.7 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family CSN8_PSD8_EIF3K PF10075.9 PFH37859.1 - 1e-13 51.5 0.0 1.6e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF43 PF01861.16 PFH37859.1 - 0.0047 16.2 0.0 0.009 15.3 0.0 1.4 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain SAC3_GANP PF03399.16 PFH37859.1 - 0.07 12.5 0.1 0.092 12.1 0.1 1.3 1 0 0 1 1 1 0 SAC3/GANP family DUF3242 PF11586.8 PFH37859.1 - 0.14 11.9 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) CRISPR_Cse2 PF09485.10 PFH37859.1 - 0.24 11.9 1.5 1.7 9.1 0.0 2.3 1 1 1 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Alg6_Alg8 PF03155.15 PFH37860.1 - 6.3e-80 269.5 31.5 1.6e-34 119.8 7.5 5.9 6 0 0 6 6 6 5 ALG6, ALG8 glycosyltransferase family Fra10Ac1 PF09725.9 PFH37861.1 - 7.5e-09 35.7 0.2 1.1e-07 32.0 0.0 2.2 2 0 0 2 2 2 1 Folate-sensitive fragile site protein Fra10Ac1 EF-hand_6 PF13405.6 PFH37862.1 - 9.4e-06 25.2 0.1 0.00039 20.1 0.1 2.7 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 PFH37862.1 - 1.2e-05 25.1 0.0 0.0013 18.6 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 PFH37862.1 - 1.2e-05 24.5 0.2 0.00011 21.5 0.1 2.6 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 PFH37862.1 - 6.2e-05 23.4 0.0 0.015 15.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PFH37862.1 - 0.0032 16.9 0.1 0.0081 15.6 0.1 1.7 1 0 0 1 1 1 1 EF hand DUF2322 PF10084.9 PFH37862.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) EF-hand_9 PF14658.6 PFH37862.1 - 0.082 13.2 0.0 2.3 8.6 0.0 2.4 3 0 0 3 3 3 0 EF-hand domain AP2 PF00847.20 PFH37863.1 - 3.4e-18 65.6 0.0 5.9e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 AP2 domain zf-RING_2 PF13639.6 PFH37864.1 - 6.3e-12 45.6 8.0 1.5e-11 44.5 8.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PFH37864.1 - 2e-09 37.1 6.7 3.9e-09 36.2 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PFH37864.1 - 3.7e-09 36.2 1.0 7.8e-09 35.1 1.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 PFH37864.1 - 1.9e-08 34.4 6.3 5.4e-08 33.0 6.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PFH37864.1 - 7.9e-07 28.8 6.0 1.8e-06 27.7 6.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH37864.1 - 1.9e-05 24.5 3.7 1.9e-05 24.5 3.7 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PFH37864.1 - 4.6e-05 23.4 3.8 0.0001 22.2 3.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PFH37864.1 - 0.00022 21.0 3.6 0.00063 19.6 3.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PFH37864.1 - 0.00062 19.8 6.1 0.001 19.0 1.9 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PFH37864.1 - 0.0075 16.1 4.0 0.018 14.9 4.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.7 PFH37864.1 - 0.083 13.0 8.2 0.24 11.6 8.2 1.8 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 PFH37864.1 - 0.36 11.0 3.0 0.85 9.8 3.0 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 PFH37864.1 - 1.8 8.2 9.1 0.13 11.9 3.8 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 PFH37864.1 - 9.8 6.1 7.6 4.7 7.1 4.2 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain GRASP55_65 PF04495.14 PFH37865.1 - 2.3e-43 147.8 0.0 6.4e-33 114.0 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 PFH37865.1 - 7.8e-10 39.0 0.0 0.00022 21.5 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 PFH37865.1 - 9.9e-09 34.9 0.0 0.0021 17.8 0.0 2.7 2 1 0 2 2 2 2 PDZ domain PDZ PF00595.24 PFH37865.1 - 0.00034 20.9 0.0 0.095 13.1 0.0 2.3 2 0 0 2 2 2 2 PDZ domain ATP-synt_ab PF00006.25 PFH37869.1 - 2.7e-62 210.2 0.0 4.4e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 PFH37869.1 - 9.7e-23 80.5 1.1 1.7e-22 79.7 1.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 PFH37869.1 - 0.0029 18.0 0.0 0.14 12.5 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 PFH37869.1 - 0.007 15.7 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_16 PF13191.6 PFH37869.1 - 0.012 16.0 0.0 0.035 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 PFH37869.1 - 0.015 14.5 0.2 0.031 13.4 0.2 1.5 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 PFH37869.1 - 0.042 13.8 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 PFH37869.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 PFH37869.1 - 0.12 12.7 0.8 0.45 10.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain Abhydrolase_1 PF00561.20 PFH37870.1 - 7.1e-20 71.7 0.0 1.6e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PFH37870.1 - 8.7e-17 61.2 0.0 1.1e-13 51.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PFH37870.1 - 1.4e-11 45.5 2.6 1.7e-09 38.6 0.1 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 PFH37870.1 - 3.6e-05 23.4 0.0 0.00059 19.4 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Ser_hydrolase PF06821.13 PFH37870.1 - 0.002 18.0 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_2 PF02230.16 PFH37870.1 - 0.016 15.0 0.0 0.51 10.1 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF676 PF05057.14 PFH37870.1 - 0.098 12.2 0.0 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) FSH1 PF03959.13 PFH37870.1 - 0.15 11.7 0.0 22 4.6 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DNA_pol_A PF00476.20 PFH37871.1 - 1.2e-73 248.3 0.0 2.1e-73 247.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A AAA_25 PF13481.6 PFH37871.1 - 1.2e-20 73.9 0.1 4e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain DNA_pol_A_exo1 PF01612.20 PFH37871.1 - 2e-19 70.0 0.0 2.8e-10 40.2 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease Toprim_2 PF13155.6 PFH37871.1 - 5.6e-07 29.9 0.0 2e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 PFH37871.1 - 7e-05 23.2 0.0 0.0002 21.8 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 PFH37871.1 - 0.0004 20.7 0.0 0.002 18.5 0.0 2.2 2 0 0 2 2 2 1 Toprim domain DnaB_C PF03796.15 PFH37871.1 - 0.00044 19.7 0.0 0.00084 18.7 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 PFH37871.1 - 0.0069 15.8 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 KaiC LRRNT PF01462.18 PFH37871.1 - 0.1 12.3 0.4 0.27 10.9 0.4 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain EGF_CA PF07645.15 PFH37873.1 - 2.6e-30 104.3 62.5 4.3e-10 39.6 10.0 5.2 5 0 0 5 5 5 4 Calcium-binding EGF domain EGF_3 PF12947.7 PFH37873.1 - 6.6e-18 64.6 53.4 3.4e-06 27.2 6.7 5.6 5 1 0 5 5 5 4 EGF domain FXa_inhibition PF14670.6 PFH37873.1 - 1.2e-11 44.7 52.7 4.8e-06 26.8 4.6 5.9 3 1 2 5 5 5 4 Coagulation Factor Xa inhibitory site cEGF PF12662.7 PFH37873.1 - 1e-10 41.3 46.4 1.8e-05 24.5 1.1 6.9 6 1 0 6 6 6 4 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 PFH37873.1 - 2.6e-08 33.8 51.9 6.1e-06 26.2 7.5 4.9 5 0 0 5 5 5 4 MSP1 EGF domain 1 hEGF PF12661.7 PFH37873.1 - 1.4e-06 28.7 48.3 0.0089 16.6 4.2 7.3 7 1 0 7 7 7 4 Human growth factor-like EGF EGF PF00008.27 PFH37873.1 - 2e-06 28.0 52.2 0.051 13.9 0.8 6.2 4 1 1 5 5 5 4 EGF-like domain Plasmod_Pvs28 PF06247.11 PFH37873.1 - 3.2e-05 24.1 57.5 0.017 15.4 7.6 5.8 5 1 0 5 5 5 3 Pvs28 EGF domain LapA_dom PF06305.11 PFH37873.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4381 PF14316.6 PFH37873.1 - 0.21 11.8 0.2 0.31 11.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Phage_holin_2_1 PF04971.12 PFH37873.1 - 0.31 11.1 0.9 0.61 10.1 0.9 1.4 1 0 0 1 1 1 0 Bacteriophage P21 holin S DUF4051 PF13260.6 PFH37873.1 - 0.43 10.4 2.7 1 9.1 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4051) CDP-OH_P_transf PF01066.21 PFH37874.1 - 3.4e-16 59.7 0.1 3.4e-16 59.7 0.1 3.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Kinesin PF00225.23 PFH37875.1 - 5.9e-06 25.4 0.0 0.00058 18.9 0.0 3.3 3 1 0 3 3 3 1 Kinesin motor domain PHM7_cyt PF14703.6 PFH37875.1 - 0.00088 19.5 2.3 0.002 18.4 2.3 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF4407 PF14362.6 PFH37875.1 - 0.25 10.7 12.2 0.24 10.7 10.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Drf_FH1 PF06346.12 PFH37875.1 - 0.8 9.4 19.8 0.069 12.9 13.4 2.4 2 0 0 2 2 2 0 Formin Homology Region 1 DUF1629 PF07791.11 PFH37876.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) WGR PF05406.15 PFH37877.1 - 0.024 14.7 0.0 0.064 13.3 0.0 1.7 1 0 0 1 1 1 0 WGR domain Zip PF02535.22 PFH37878.1 - 1e-29 103.8 9.7 6.7e-29 101.2 9.7 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Ank_2 PF12796.7 PFH37879.1 - 1.3e-07 32.1 0.0 3.1e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PFH37879.1 - 3.7e-06 27.1 0.0 5.8e-05 23.3 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH37879.1 - 0.00042 20.5 0.0 1.1 10.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 PFH37879.1 - 0.0014 18.9 0.0 1.1 9.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 PFH37879.1 - 0.06 13.9 0.1 3.8 8.2 0.0 2.7 2 1 2 4 4 4 0 Ankyrin repeats (many copies) VIR_N PF15912.5 PFH37879.1 - 0.1 12.2 1.4 0.14 11.7 1.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal CAP_N PF01213.19 PFH37879.1 - 0.15 11.5 1.9 0.21 11.0 1.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mesd PF10185.9 PFH37880.1 - 1.7e-05 24.8 0.0 2.2e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor AAA_22 PF13401.6 PFH37881.1 - 3.3e-08 33.9 0.0 1.4e-07 31.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PFH37881.1 - 0.01 16.2 0.1 0.04 14.3 0.1 2.1 1 0 0 1 1 1 0 AAA ATPase domain RNase_H2_suC PF08615.11 PFH37882.1 - 5.2e-09 36.4 0.0 2.4e-07 31.0 0.0 2.6 2 1 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Rab3-GTPase_cat PF13890.6 PFH37883.1 - 0.082 12.5 0.1 0.082 12.5 0.1 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein catalytic subunit WD40 PF00400.32 PFH37885.1 - 0.03 15.2 0.3 8.4 7.4 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat GILT PF03227.16 PFH37886.1 - 1.8e-28 98.9 1.8 7.9e-28 96.8 0.7 2.1 1 1 1 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_4 PF13462.6 PFH37886.1 - 0.096 12.8 0.1 0.91 9.7 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin DUF5048 PF16467.5 PFH37886.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5048) SR-25 PF10500.9 PFH37887.1 - 0.00017 21.3 21.0 0.00017 21.3 21.0 1.6 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 PFH37887.1 - 0.13 12.9 15.0 0.24 12.1 15.0 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein CCDC106 PF15794.5 PFH37887.1 - 0.88 9.2 16.7 1.3 8.7 16.6 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4337 PF14235.6 PFH37887.1 - 0.99 9.5 6.7 1.6 8.8 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4140 PF13600.6 PFH37887.1 - 1.6 9.2 5.1 1.5 9.3 2.1 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TSGP1 PF07771.11 PFH37887.1 - 6.5 6.9 9.6 14 5.8 9.6 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 APG6_N PF17675.1 PFH37887.1 - 9 6.8 12.6 24 5.5 12.6 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region CHD5 PF04420.14 PFH37887.1 - 9.8 6.0 10.3 16 5.3 10.3 1.4 1 0 0 1 1 1 0 CHD5-like protein ERCC4 PF02732.15 PFH37888.1 - 7.5e-13 49.0 0.0 3.6e-12 46.8 0.0 2.2 1 1 0 1 1 1 1 ERCC4 domain Tet_res_leader PF08050.12 PFH37888.1 - 0.67 9.8 3.3 0.4 10.6 0.4 2.2 2 0 0 2 2 2 0 Tetracycline resistance leader peptide Peptidase_M24 PF00557.24 PFH37889.1 - 2.6e-41 141.6 0.0 4e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 PFH37889.1 - 1.1e-35 123.1 0.0 1.1e-32 113.4 0.0 3.0 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 PFH37889.1 - 9.7e-22 76.8 0.3 2.6e-21 75.4 0.3 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 PFH37889.1 - 4.9e-21 75.8 0.0 7.6e-20 71.9 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Ank_2 PF12796.7 PFH37890.1 - 1.5e-40 137.6 2.0 5.4e-17 62.1 0.1 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PFH37890.1 - 3.7e-32 110.3 2.8 1.7e-13 50.8 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PFH37890.1 - 8.4e-23 78.0 0.3 2.8e-06 27.2 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 PFH37890.1 - 4.7e-22 77.4 2.4 2.2e-07 31.0 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 PFH37890.1 - 6.5e-22 77.3 2.2 2.8e-09 37.1 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Histone_H2A_C PF16211.5 PFH37891.1 - 1.9e-18 65.9 0.4 1.9e-18 65.9 0.4 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 PFH37891.1 - 2.5e-14 53.8 0.0 3.4e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PFH37891.1 - 0.0011 19.2 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L7Ae PF01248.26 PFH37892.1 - 2.5e-21 75.2 0.9 5.3e-21 74.1 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RBM39linker PF15519.6 PFH37892.1 - 1.4 10.0 4.1 26 6.0 0.0 3.1 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein TBPIP PF07106.13 PFH37893.1 - 0.0029 17.5 0.0 0.0068 16.3 0.0 1.6 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain RNA_pol_L_2 PF13656.6 PFH37894.1 - 5.3e-28 96.6 0.0 7.4e-28 96.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 PFH37894.1 - 4.3e-08 32.5 0.0 5.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TAXi_N PF14543.6 PFH37895.1 - 1.8e-18 67.4 7.6 6.1e-18 65.7 7.6 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 PFH37895.1 - 4.1e-17 62.6 0.0 9.2e-09 35.1 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 PFH37895.1 - 4.3e-09 36.4 0.0 2.2e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal NOG1_N PF17835.1 PFH37896.1 - 1.6e-45 154.9 0.1 5.4e-45 153.2 0.1 1.9 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 PFH37896.1 - 3e-24 84.7 0.1 6.4e-24 83.7 0.1 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 PFH37896.1 - 2.3e-23 81.7 2.5 2.3e-23 81.7 0.8 2.0 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 PFH37896.1 - 3.1e-18 65.9 0.0 7e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PFH37896.1 - 1.8e-11 43.8 0.1 2.9e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PFH37896.1 - 0.0074 16.2 0.2 0.89 9.4 0.0 3.0 2 1 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 PFH37896.1 - 0.026 13.8 0.0 0.026 13.8 0.0 2.0 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.23 PFH37896.1 - 0.047 13.8 4.5 2.5 8.1 0.1 3.2 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.6 PFH37896.1 - 0.25 11.7 0.0 0.25 11.7 0.0 3.1 2 2 0 2 2 2 0 AAA ATPase domain Ribosomal_L22 PF00237.19 PFH37897.1 - 8.6e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RAB3GAP2_N PF14655.6 PFH37898.1 - 1.1e-21 77.7 0.0 2.8e-21 76.3 0.0 1.7 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Glycos_transf_2 PF00535.26 PFH37900.1 - 3.3e-22 79.1 0.0 6.8e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PFH37900.1 - 2e-10 41.0 0.3 4.8e-10 39.8 0.3 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 PFH37900.1 - 0.00036 20.1 0.0 0.00083 19.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 PFH37900.1 - 0.0017 18.3 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 PFH37900.1 - 0.0049 17.6 0.0 0.02 15.6 0.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.9 PFH37900.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 OTU PF02338.19 PFH37901.1 - 1.6e-16 60.9 0.0 2.8e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PFH37901.1 - 0.0078 15.7 1.0 2.3 7.6 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain DUF4304 PF14137.6 PFH37901.1 - 0.062 13.5 0.0 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) zf-C3HC4 PF00097.25 PFH37902.1 - 3e-06 27.0 14.2 3e-06 27.0 14.2 2.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PFH37902.1 - 4.9e-06 26.8 13.5 4.9e-06 26.8 13.5 3.0 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 PFH37902.1 - 0.00017 21.6 11.2 0.00017 21.6 11.2 2.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 PFH37902.1 - 0.0002 21.3 14.0 0.0002 21.3 14.0 2.8 3 0 0 3 3 3 1 zinc-RING finger domain Sina PF03145.16 PFH37902.1 - 0.00041 20.4 1.6 0.00041 20.4 1.6 4.5 2 1 1 4 4 4 1 Seven in absentia protein family zf-C3HC4_2 PF13923.6 PFH37902.1 - 0.0009 19.0 12.8 0.0009 19.0 12.8 2.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 PFH37902.1 - 0.014 15.9 7.9 0.014 15.9 7.9 3.0 1 1 1 2 2 2 0 TRAF-like zinc-finger zf-C3HC4_4 PF15227.6 PFH37902.1 - 0.04 14.1 11.1 0.24 11.6 11.1 2.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PFH37902.1 - 0.74 9.7 19.5 0.44 10.4 14.4 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Kinase-like PF14531.6 PFH37903.1 - 8.9e-27 94.1 0.0 1.3e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH37903.1 - 1.3e-22 80.4 0.0 2.4e-19 69.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH37903.1 - 1.5e-07 31.0 0.0 6.5e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH37903.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family BESS PF02944.20 PFH37904.1 - 0.068 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 BESS motif HEPN_DZIP3 PF18738.1 PFH37904.1 - 0.14 11.9 0.1 0.17 11.6 0.1 1.1 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN Thioredoxin PF00085.20 PFH37905.1 - 3.8e-06 26.8 0.0 4e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 PFH37905.1 - 0.1 12.8 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like PepSY_TM PF03929.16 PFH37905.1 - 0.17 11.5 0.5 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 PepSY-associated TM region Vps52 PF04129.12 PFH37906.1 - 4.4e-67 227.0 0.0 5.6e-66 223.3 0.0 2.0 1 1 0 1 1 1 1 Vps52 / Sac2 family COG6 PF06419.11 PFH37906.1 - 0.00011 20.6 0.2 0.00011 20.6 0.2 2.1 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 Sec3_C PF09763.9 PFH37906.1 - 0.00016 20.3 2.0 0.041 12.3 0.0 2.6 2 1 0 2 2 2 2 Exocyst complex component Sec3 SR-25 PF10500.9 PFH37907.1 - 3.5e-07 30.1 42.8 3.5e-07 30.1 42.8 2.2 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Ax_dynein_light PF10211.9 PFH37910.1 - 4e-57 193.2 1.7 5e-57 192.9 1.7 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain HAP1_N PF04849.13 PFH37910.1 - 0.0024 17.2 6.7 0.0034 16.7 6.7 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF4600 PF15372.6 PFH37910.1 - 0.0052 17.2 4.1 0.053 14.0 0.8 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4600) Jnk-SapK_ap_N PF09744.9 PFH37910.1 - 0.026 14.8 3.7 0.05 13.8 3.7 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF664 PF04978.12 PFH37910.1 - 0.13 12.6 2.4 3.4 8.1 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF664) DivIC PF04977.15 PFH37910.1 - 0.16 11.8 2.8 0.42 10.4 2.3 2.0 1 1 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 PFH37910.1 - 0.17 12.3 6.1 0.5 10.9 6.1 1.8 1 0 0 1 1 1 0 Cell division protein ZapB DUF1192 PF06698.11 PFH37910.1 - 0.21 11.7 6.1 0.16 12.1 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) F-box-like PF12937.7 PFH37911.1 - 4.6e-05 23.2 1.0 4.6e-05 23.2 1.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PFH37911.1 - 0.054 13.4 0.3 3 7.8 0.1 2.8 2 0 0 2 2 2 0 F-box domain PHD_4 PF16866.5 PFH37913.1 - 0.024 14.7 2.2 0.049 13.7 0.5 2.1 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 PFH37913.1 - 5.5 7.0 8.2 0.27 11.2 2.2 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Rotamase_3 PF13616.6 PFH37914.1 - 3.5e-22 79.1 0.0 4.3e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 PFH37914.1 - 3.7e-22 79.1 0.0 4.2e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 PFH37914.1 - 1.2e-08 35.9 0.0 1.3e-08 35.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF4148 PF13663.6 PFH37914.1 - 0.0046 17.1 0.0 0.0071 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4148) Acylphosphatase PF00708.18 PFH37915.1 - 4.4e-25 87.9 0.4 5.1e-25 87.7 0.4 1.1 1 0 0 1 1 1 1 Acylphosphatase Lectin_leg-like PF03388.13 PFH37917.1 - 3.1e-16 59.4 0.0 4.8e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 Legume-like lectin family DUF3138 PF11336.8 PFH37917.1 - 0.039 12.6 4.0 0.068 11.8 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2383 PF09537.10 PFH37917.1 - 0.085 13.2 2.4 1.3 9.4 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) Lectin_N PF03954.14 PFH37917.1 - 0.15 11.8 1.1 0.68 9.7 0.1 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.12 PFH37917.1 - 0.51 10.4 1.1 10 6.1 0.0 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.6 PFH37917.1 - 0.52 9.7 4.4 0.1 12.0 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) SKG6 PF08693.10 PFH37917.1 - 0.68 9.4 2.3 1.4 8.4 2.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rcd1 PF04078.13 PFH37919.1 - 1.1e-124 414.9 0.5 1.3e-124 414.6 0.5 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Bromodomain PF00439.25 PFH37920.1 - 5.2e-33 113.0 0.1 9.9e-17 60.8 0.0 2.3 2 0 0 2 2 2 2 Bromodomain DUF1077 PF06417.12 PFH37921.1 - 1.3e-29 102.6 0.0 1.8e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) vATP-synt_AC39 PF01992.16 PFH37922.1 - 1.7e-92 310.5 1.8 2e-92 310.3 1.8 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit YfbU PF03887.14 PFH37922.1 - 0.04 13.9 0.3 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 YfbU domain HSP20 PF00011.21 PFH37923.1 - 1.1e-19 70.4 0.6 1.4e-19 70.1 0.6 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PFH37923.1 - 1.6e-08 34.0 0.0 2.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 PFH37923.1 - 0.027 14.5 0.8 0.035 14.2 0.1 1.5 2 0 0 2 2 2 0 GvpH TMEM72 PF16054.5 PFH37924.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 72 Jiraiya PF15038.6 PFH37926.1 - 0.013 14.9 6.3 0.019 14.4 6.3 1.2 1 0 0 1 1 1 0 Jiraiya DUF599 PF04654.12 PFH37926.1 - 0.19 11.2 7.2 0.26 10.7 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF599 SRTM1 PF15872.5 PFH37926.1 - 3.9 7.7 8.6 0.52 10.5 2.1 2.4 1 1 1 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Acetyltransf_1 PF00583.25 PFH37927.1 - 1.6e-09 38.0 0.1 4.6e-08 33.3 0.1 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PFH37927.1 - 5e-07 30.1 0.0 1.3e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PFH37927.1 - 7.4e-07 29.1 0.1 5.3e-05 23.1 0.0 2.6 3 0 0 3 3 3 1 FR47-like protein Acetyltransf_10 PF13673.7 PFH37927.1 - 1.2e-06 28.5 0.1 0.00036 20.5 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PFH37927.1 - 0.0024 17.9 0.0 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 PFH37927.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Glyco_transf_7C PF02709.14 PFH37928.1 - 8.8e-08 31.7 0.1 1.7e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 PFH37928.1 - 1.5e-07 31.1 0.0 6.6e-06 25.8 0.0 2.4 2 0 0 2 2 2 1 N-terminal region of glycosyl transferase group 7 UQ_con PF00179.26 PFH37929.1 - 1.2e-24 86.6 0.0 2.1e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PFH37929.1 - 0.061 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain ABC1 PF03109.16 PFH37930.1 - 4e-11 43.1 0.0 7.5e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 ABC1 family UbiA PF01040.18 PFH37931.1 - 9.9e-53 179.0 12.5 9.9e-53 179.0 12.5 3.2 3 1 0 3 3 3 1 UbiA prenyltransferase family 2OG-FeII_Oxy_2 PF13532.6 PFH37932.1 - 6.4e-24 85.2 0.0 1.8e-21 77.3 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily NOG1 PF06858.14 PFH37934.1 - 6.9e-13 48.2 0.5 1.4e-07 31.1 0.0 3.2 3 0 0 3 3 3 2 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 PFH37934.1 - 0.00055 20.0 0.0 0.002 18.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PFH37934.1 - 0.032 13.8 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 PFH37934.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF3209 PF11483.8 PFH37934.1 - 2 8.9 11.3 4.2 7.8 1.4 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3209) GLE1 PF07817.13 PFH37936.1 - 1.7e-32 112.6 0.4 2.9e-32 111.9 0.4 1.3 1 0 0 1 1 1 1 GLE1-like protein Caldesmon PF02029.15 PFH37936.1 - 3.9e-10 39.1 35.8 5.7e-10 38.6 35.8 1.2 1 0 0 1 1 1 1 Caldesmon SAPS PF04499.15 PFH37936.1 - 6.5 5.4 18.1 11 4.7 18.1 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PALP PF00291.25 PFH37937.1 - 2.5e-67 227.3 0.1 3.1e-67 227.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3879 PF12995.7 PFH37937.1 - 0.12 12.1 0.0 7.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3879) Na_H_Exchanger PF00999.21 PFH37939.1 - 3.7e-39 134.6 25.4 3.7e-39 134.6 25.4 1.9 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family ECF_trnsprt PF12822.7 PFH37939.1 - 0.77 9.8 22.7 0.24 11.5 0.9 2.6 2 1 0 2 2 2 0 ECF transporter, substrate-specific component Cupin_8 PF13621.6 PFH37941.1 - 3.7e-19 69.4 0.0 1.5e-18 67.5 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain SR-25 PF10500.9 PFH37941.1 - 0.018 14.6 0.7 0.018 14.6 0.7 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cupin_4 PF08007.12 PFH37941.1 - 0.056 12.9 0.0 0.39 10.1 0.0 2.1 1 1 0 1 1 1 0 Cupin superfamily protein Sporozoite_P67 PF05642.11 PFH37941.1 - 4.2 5.3 4.7 5.7 4.9 4.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DEAD PF00270.29 PFH37942.1 - 6.4e-35 120.5 0.0 2.4e-34 118.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PFH37942.1 - 6.5e-22 78.0 0.0 2.3e-21 76.2 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH37942.1 - 0.00021 21.4 0.0 0.00061 19.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PFH37942.1 - 0.0086 16.4 0.5 0.052 13.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain Phage_integrase PF00589.22 PFH37943.1 - 2.3e-19 69.8 0.0 5.1e-19 68.7 0.0 1.6 2 0 0 2 2 2 1 Phage integrase family SAP PF02037.27 PFH37943.1 - 9.1e-05 22.1 0.1 0.00028 20.5 0.1 1.9 1 0 0 1 1 1 1 SAP domain DZR PF12773.7 PFH37943.1 - 0.0012 18.8 2.4 0.0029 17.6 0.4 2.4 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 PFH37943.1 - 0.0027 17.4 3.4 0.0055 16.4 3.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zf-NADH-PPase PF09297.11 PFH37943.1 - 0.014 15.0 2.1 0.014 15.0 2.1 3.2 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF3464 PF11947.8 PFH37943.1 - 0.023 14.4 0.5 0.083 12.6 0.5 1.9 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 zinc_ribbon_15 PF17032.5 PFH37943.1 - 0.026 15.3 1.1 0.026 15.3 1.1 2.0 2 0 0 2 2 2 0 zinc-ribbon family Phage_int_SAM_4 PF13495.6 PFH37943.1 - 0.18 12.3 0.1 0.51 10.8 0.0 1.7 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_TAC_2 PF06894.11 PFH37943.1 - 0.21 11.4 0.0 0.43 10.4 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G Ribosomal_S21e PF01249.18 PFH37944.1 - 8.8e-39 131.5 0.0 9.7e-39 131.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Peptidase_M41 PF01434.18 PFH37945.1 - 2.5e-56 190.6 0.1 3.8e-56 190.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PFH37945.1 - 5.3e-42 143.4 0.0 1.3e-41 142.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Helicase_C PF00271.31 PFH37945.1 - 2e-14 53.8 0.0 7.2e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 PFH37945.1 - 1.9e-12 47.3 0.3 5.6e-11 42.5 0.0 3.2 3 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_lid_3 PF17862.1 PFH37945.1 - 4.3e-10 39.2 0.1 4.3e-10 39.2 0.1 2.2 2 0 0 2 2 2 1 AAA+ lid domain RecQ_Zn_bind PF16124.5 PFH37945.1 - 1.8e-06 28.5 0.3 8e-06 26.5 0.3 2.2 1 0 0 1 1 1 1 RecQ zinc-binding AAA_16 PF13191.6 PFH37945.1 - 2.3e-06 28.1 0.5 0.00032 21.1 0.1 3.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 PFH37945.1 - 4.9e-06 26.6 0.0 1.9e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 PFH37945.1 - 0.00019 20.7 0.0 0.00038 19.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain ResIII PF04851.15 PFH37945.1 - 0.00047 20.2 0.0 0.047 13.7 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 PFH37945.1 - 0.00066 19.5 0.0 0.0021 17.8 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PFH37945.1 - 0.005 17.1 0.0 0.13 12.6 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.6 PFH37945.1 - 0.0079 15.9 2.7 3.1 7.4 0.4 3.0 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 PFH37945.1 - 0.008 16.4 0.1 0.038 14.1 0.1 2.3 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 PFH37945.1 - 0.023 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 PFH37945.1 - 0.032 14.8 0.0 0.092 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PFH37945.1 - 0.056 13.7 0.1 0.056 13.7 0.1 2.3 3 0 0 3 3 1 0 AAA domain TsaE PF02367.17 PFH37945.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 PFH37945.1 - 0.12 11.8 0.0 0.41 10.0 0.0 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 PFH37945.1 - 0.12 11.8 1.6 1.2 8.5 0.1 2.8 3 0 0 3 3 3 0 PhoH-like protein NACHT PF05729.12 PFH37945.1 - 0.17 11.8 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 PFH37945.1 - 4.2 7.8 5.4 0.62 10.5 0.0 2.4 3 0 0 3 3 1 0 AAA domain LEA_6 PF10714.9 PFH37945.1 - 8.5 6.5 7.7 0.76 9.9 0.8 3.0 2 0 0 2 2 1 0 Late embryogenesis abundant protein 18 SAG PF04092.13 PFH37947.1 - 4.5e-11 43.7 0.8 8.3e-11 42.8 0.2 1.7 2 0 0 2 2 2 1 SRS domain PRIMA1 PF16101.5 PFH37947.1 - 0.92 9.6 13.7 9.3 6.3 11.3 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PFH37947.1 - 3.1 7.2 8.5 4.6 6.6 8.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3161 PF11362.8 PFH37949.1 - 1.2e-16 60.4 0.0 2.3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3161) SKA2 PF16740.5 PFH37949.1 - 1.8e-16 59.9 1.9 3.1e-16 59.1 1.9 1.3 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Glycos_transf_2 PF00535.26 PFH37950.1 - 1.9e-25 89.7 0.0 3.4e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PFH37950.1 - 6.5e-07 29.6 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 PFH37950.1 - 6.8e-05 22.9 0.0 0.00046 20.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 PFH37950.1 - 0.0038 16.8 0.1 0.0077 15.9 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Pterin_bind PF00809.22 PFH37951.1 - 5e-68 229.4 0.0 7.7e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 PFH37951.1 - 8.2e-21 74.6 0.0 1.7e-09 38.2 0.0 2.6 1 1 1 2 2 2 2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Exo_endo_phos PF03372.23 PFH37952.1 - 8.6e-22 77.8 0.0 2.5e-20 73.0 0.0 3.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CHC2 PF01807.20 PFH37952.1 - 0.098 12.5 3.8 0.2 11.5 3.8 1.4 1 0 0 1 1 1 0 CHC2 zinc finger dCMP_cyt_deam_1 PF00383.23 PFH37953.1 - 8.1e-18 64.2 1.4 1.2e-17 63.7 1.4 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PFH37953.1 - 1.5e-14 53.9 0.9 2.7e-14 53.1 0.9 1.4 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 PFH37953.1 - 0.0023 18.0 4.1 0.0067 16.5 4.1 1.7 1 1 0 1 1 1 1 Bd3614-like deaminase DUF4491 PF14898.6 PFH37955.1 - 0.13 12.7 5.4 0.23 11.9 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) RRM_1 PF00076.22 PFH37956.1 - 0.011 15.5 0.5 5.7 6.8 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MraZ PF02381.18 PFH37957.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like Nucleoporin2 PF04096.14 PFH37959.1 - 2.3e-39 134.9 0.0 3.3e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 PFH37959.1 - 7.3e-28 97.3 383.0 1.7e-09 38.4 36.5 13.6 4 3 11 15 15 15 11 Nucleoporin FG repeat region Nup96 PF12110.8 PFH37959.1 - 3e-16 59.4 0.0 6e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Nuclear protein 96 zf-met PF12874.7 PFH37961.1 - 1.3e-07 31.7 0.6 2.6e-07 30.8 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PFH37961.1 - 0.0001 22.5 3.8 0.0002 21.6 3.8 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PFH37961.1 - 0.018 15.4 0.2 0.034 14.5 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Pribosyltran PF00156.27 PFH37962.1 - 2.1e-13 50.1 0.0 3.1e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 PFH37962.1 - 0.036 13.6 0.1 0.054 13.0 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase VWA PF00092.28 PFH37963.1 - 2.1e-56 190.9 0.0 3.2e-18 66.6 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 PFH37963.1 - 2.6e-25 89.1 0.0 1.3e-06 29.0 0.0 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain OMPdecase PF00215.24 PFH37964.1 - 1.3e-28 100.1 0.0 1.1e-27 97.1 0.0 1.9 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DKCLD PF08068.12 PFH37964.1 - 0.03 14.4 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 DKCLD (NUC011) domain MIG-14_Wnt-bd PF06664.12 PFH37965.1 - 0.0013 18.1 0.9 0.0031 16.8 0.1 1.8 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion DUF267 PF03268.14 PFH37965.1 - 0.07 12.0 0.1 0.07 12.0 0.1 1.8 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF267 DUF2721 PF11026.8 PFH37965.1 - 0.17 11.8 7.0 0.035 14.0 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Phage_holin_3_6 PF07332.11 PFH37965.1 - 3.6 7.7 8.8 3.9 7.6 8.0 1.4 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III EF-hand_1 PF00036.32 PFH37966.1 - 2e-16 58.2 5.5 9.2e-06 24.9 0.5 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PFH37966.1 - 1.9e-15 55.4 3.4 0.0005 19.8 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 PFH37966.1 - 6.1e-13 47.6 4.2 4.5e-05 22.7 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 PFH37966.1 - 2.4e-12 47.1 8.1 1.6e-06 28.4 3.4 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 PFH37966.1 - 7.2e-07 29.0 6.0 0.038 13.9 0.4 3.5 3 0 0 3 3 3 3 EF-hand domain pair DUF5069 PF16798.5 PFH37966.1 - 0.013 15.7 0.1 0.039 14.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) CCDC73 PF15818.5 PFH37966.1 - 0.022 12.7 0.1 0.028 12.3 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family SPARC_Ca_bdg PF10591.9 PFH37966.1 - 0.077 13.3 1.3 4.4 7.7 0.3 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 PFH37966.1 - 7.6 6.8 7.0 2 8.7 0.7 2.9 3 1 1 4 4 4 0 Dockerin type I domain DAGK_acc PF00609.19 PFH37968.1 - 5.1e-16 59.4 0.0 1.1e-15 58.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 PFH37968.1 - 9.6e-13 47.9 0.2 8.2e-11 41.6 0.1 2.4 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 PFH37968.1 - 0.055 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP-NAD kinase RRM_1 PF00076.22 PFH37971.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoU_methylas_C PF12105.8 PFH37971.1 - 0.015 15.0 0.2 0.034 13.8 0.2 1.6 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal Myb_DNA-binding PF00249.31 PFH37972.1 - 0.0028 17.8 0.0 0.0056 16.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Syja_N PF02383.18 PFH37973.1 - 8.4e-25 87.7 0.0 1.1e-13 51.2 0.0 3.8 3 1 0 3 3 3 3 SacI homology domain Kazal_1 PF00050.21 PFH37975.1 - 8e-103 336.3 149.3 9.5e-10 38.3 2.2 13.6 6 3 7 13 13 13 13 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 PFH37975.1 - 9.3e-87 285.0 159.7 2.6e-08 33.9 3.8 13.7 12 1 1 13 13 13 13 Kazal-type serine protease inhibitor domain DUF809 PF05663.11 PFH37976.1 - 0.42 10.7 2.4 0.95 9.6 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF809) CCSAP PF15748.5 PFH37976.1 - 0.99 9.5 12.6 1.5 8.9 12.6 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated MMR_HSR1 PF01926.23 PFH37978.1 - 3.5e-10 40.0 0.0 1.5e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PFH37978.1 - 0.0024 17.9 0.0 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 PFH37978.1 - 0.008 15.7 0.0 0.37 10.3 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PFH37978.1 - 0.019 14.9 0.0 0.11 12.4 0.0 2.2 1 1 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 PFH37978.1 - 0.2 11.4 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein HEAT_PBS PF03130.16 PFH37978.1 - 0.31 11.8 2.2 8.7 7.3 0.0 3.4 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Cad PF03596.13 PFH37979.1 - 0.073 13.0 3.3 0.045 13.6 0.8 1.8 2 0 0 2 2 2 0 Cadmium resistance transporter Carb_anhydrase PF00194.21 PFH37980.1 - 9.9e-27 94.1 0.2 6.5e-15 55.4 0.0 3.3 3 0 0 3 3 3 3 Eukaryotic-type carbonic anhydrase GDA1_CD39 PF01150.17 PFH37981.1 - 6.1e-22 77.9 0.0 2.2e-05 23.3 0.0 4.9 4 1 0 4 4 4 4 GDA1/CD39 (nucleoside phosphatase) family BBL5 PF07289.11 PFH37983.1 - 1.6e-64 218.1 0.0 2.1e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein zf-C3HC4_3 PF13920.6 PFH37983.1 - 4e-11 42.6 12.2 7.2e-11 41.8 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PFH37983.1 - 2.7e-05 23.9 11.8 5.3e-05 23.0 11.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 GRAM PF02893.20 PFH37983.1 - 0.00026 20.9 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 PFH37983.1 - 0.0012 19.0 0.1 2.1 8.6 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 Voldacs PF03517.13 PFH37983.1 - 0.037 14.1 0.7 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling zf-RING_5 PF14634.6 PFH37983.1 - 2.1 8.4 12.7 4.7 7.3 12.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DnaJ PF00226.31 PFH37985.1 - 2.9e-22 78.5 1.1 5.5e-22 77.7 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 PFH37985.1 - 1.9e-13 50.5 0.8 5.5e-13 49.1 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) RPT PF13446.6 PFH37985.1 - 0.0015 18.4 0.6 0.0053 16.7 0.0 2.2 3 0 0 3 3 3 1 A repeated domain in UCH-protein TPR_2 PF07719.17 PFH37985.1 - 0.081 13.1 2.8 3.7 7.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 PFH37985.1 - 0.19 12.6 1.2 1.4 9.9 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 PFH37985.1 - 1.9 9.2 7.6 0.26 12.0 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SAC3_GANP PF03399.16 PFH37986.1 - 3.7e-17 62.6 3.8 1.9e-15 57.1 3.8 2.3 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 PFH37986.1 - 0.034 14.1 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Acetyltransf_1 PF00583.25 PFH37988.1 - 1.1e-08 35.3 0.0 1.6e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PFH37988.1 - 8.7e-08 32.5 0.1 1.7e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PFH37988.1 - 2.1e-06 27.7 0.0 4e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PFH37988.1 - 0.015 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF4605 PF15378.6 PFH37989.1 - 0.0059 16.4 3.1 0.0093 15.8 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4605) Pkinase PF00069.25 PFH37990.1 - 1.2e-12 47.7 0.0 1.9e-06 27.5 0.0 3.1 3 1 0 3 3 3 2 Protein kinase domain PMI_typeI PF01238.21 PFH37991.1 - 8.3e-69 232.6 0.1 1.7e-61 208.5 0.0 4.0 2 2 1 3 3 3 3 Phosphomannose isomerase type I TPR_2 PF07719.17 PFH37992.1 - 6.3 7.2 16.1 1 9.6 0.2 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3622 PF12286.8 PFH37992.1 - 9.1 6.7 6.6 0.33 11.3 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3622) Methyltr_RsmB-F PF01189.17 PFH37993.1 - 1e-16 61.2 0.0 1.6e-07 31.2 0.0 3.4 4 0 0 4 4 4 2 16S rRNA methyltransferase RsmB/F GTP_EFTU PF00009.27 PFH37994.1 - 8.7e-56 188.5 0.0 1.6e-55 187.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 PFH37994.1 - 5.2e-33 113.4 0.0 1.3e-32 112.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 PFH37994.1 - 1.7e-30 104.9 0.1 3.4e-30 104.0 0.1 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 PFH37994.1 - 6e-25 87.1 0.0 1.5e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PFH37994.1 - 2e-12 47.3 0.1 4.3e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 PFH37994.1 - 4.1e-05 23.4 0.1 9.1e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Condensation PF00668.20 PFH37994.1 - 0.016 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Condensation domain AvrPtoB_bdg PF16847.5 PFH37994.1 - 0.05 14.1 0.0 0.89 10.1 0.0 2.6 3 0 0 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain Rad60-SLD_2 PF13881.6 PFH37995.1 - 0.033 14.3 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MAR_sialic_bdg PF10564.9 PFH37996.1 - 9.1e-09 35.2 1.4 0.00019 21.4 0.0 2.7 1 1 1 2 2 2 2 Sialic-acid binding micronemal adhesive repeat HA2 PF04408.23 PFH37997.1 - 5.1e-19 68.6 0.0 5.1e-19 68.6 0.0 4.0 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PFH37997.1 - 2.6e-16 59.8 0.0 5.4e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PFH37997.1 - 2.1e-12 47.4 0.0 4.9e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PFH37997.1 - 0.00024 20.9 0.5 0.0054 16.5 0.5 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 PFH37997.1 - 0.0028 16.7 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 PFH37997.1 - 0.0083 16.4 0.0 0.045 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PFH37997.1 - 0.045 14.1 0.1 15 5.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 PFH37997.1 - 0.13 11.7 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 PFH37997.1 - 0.15 12.6 0.0 0.82 10.2 0.0 2.2 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 PFH37997.1 - 0.16 12.2 1.1 15 5.8 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 PFH37997.1 - 0.62 10.5 0.0 0.62 10.5 0.0 3.7 3 1 0 4 4 2 0 AAA domain MMR_HSR1 PF01926.23 PFH37998.1 - 9.4e-07 28.9 0.1 2.9e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PFH37998.1 - 0.00036 20.1 0.1 0.39 10.2 0.1 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PFH37998.1 - 0.0049 16.8 0.0 0.11 12.4 0.0 2.4 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 PFH37998.1 - 0.13 12.3 0.5 2.8 8.0 0.0 2.7 3 0 0 3 3 3 0 Dynamin family Spore_IV_A PF09547.10 PFH37998.1 - 0.17 10.8 0.1 0.27 10.1 0.1 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) BT1 PF03092.16 PFH37999.1 - 3.6e-86 289.5 22.2 4.4e-63 213.3 10.5 2.1 1 1 1 2 2 2 2 BT1 family MFS_1 PF07690.16 PFH37999.1 - 3.9 6.3 45.9 0.077 11.9 0.5 4.5 2 2 2 4 4 4 0 Major Facilitator Superfamily Med9 PF07544.13 PFH38001.1 - 0.047 13.8 3.4 0.047 13.8 3.4 2.7 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Kinase-like PF14531.6 PFH38003.1 - 2e-53 181.6 0.0 2.4e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PFH38003.1 - 5.5e-22 78.4 0.0 6.3e-21 74.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH38003.1 - 8.4e-08 31.8 0.0 1.7e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PFH38003.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP-synt_E_2 PF08112.11 PFH38003.1 - 0.062 13.6 0.3 0.12 12.7 0.3 1.3 1 0 0 1 1 1 0 ATP synthase epsilon subunit RabGAP-TBC PF00566.18 PFH38006.1 - 8.1e-20 71.4 0.0 5.3e-19 68.7 0.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 PFH38006.1 - 2.8e-10 40.0 0.0 0.0001 21.8 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PFH38006.1 - 1.2e-05 24.8 0.0 1.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 PFH38006.1 - 0.0014 19.1 0.0 0.61 10.6 0.0 2.5 2 0 0 2 2 2 2 Rhodanese-like domain EF_assoc_2 PF08356.12 PFH38008.1 - 0.079 13.0 0.0 0.089 12.8 0.0 1.1 1 0 0 1 1 1 0 EF hand associated Abhydrolase_3 PF07859.13 PFH38009.1 - 1.4e-34 119.8 0.0 1.3e-29 103.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 PFH38009.1 - 5.6e-12 45.2 0.0 9.1e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Cript PF10235.9 PFH38010.1 - 5.4e-14 52.5 7.0 5.4e-14 52.5 7.0 1.8 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT zinc_ribbon_15 PF17032.5 PFH38010.1 - 0.0041 17.8 11.6 0.054 14.3 5.7 2.7 2 1 0 2 2 2 1 zinc-ribbon family DZR PF12773.7 PFH38010.1 - 0.013 15.5 11.6 0.087 12.9 7.0 2.5 1 1 1 2 2 2 0 Double zinc ribbon Peptidase_C74 PF12387.8 PFH38010.1 - 0.061 12.8 1.9 0.06 12.8 1.9 1.1 1 0 0 1 1 1 0 Pestivirus NS2 peptidase DiS_P_DiS PF06750.13 PFH38010.1 - 0.14 12.3 10.0 0.05 13.7 5.2 2.3 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Gin PF10764.9 PFH38010.1 - 0.17 11.8 5.6 0.39 10.7 0.3 2.9 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin zinc_ribbon_2 PF13240.6 PFH38010.1 - 0.39 10.5 0.1 0.39 10.5 0.1 3.7 3 1 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 PFH38010.1 - 0.75 9.8 12.1 4 7.5 12.1 2.1 1 1 0 1 1 1 0 zinc-ribbons zf-C3HC4_3 PF13920.6 PFH38010.1 - 0.87 9.5 14.3 1.1 9.1 3.2 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2039 PF10217.9 PFH38010.1 - 2.5 8.5 13.5 0.47 10.8 7.8 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) PLATZ PF04640.14 PFH38010.1 - 2.8 8.6 11.7 0.42 11.3 0.6 2.9 1 1 2 3 3 3 0 PLATZ transcription factor EF-hand_1 PF00036.32 PFH38011.1 - 1.4e-30 102.5 8.5 4.1e-09 35.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PFH38011.1 - 3.2e-29 101.2 2.9 8.8e-15 54.9 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH38011.1 - 6.8e-26 88.0 7.2 2.3e-09 36.4 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PFH38011.1 - 3.8e-23 81.1 12.9 1.9e-10 40.4 0.4 3.8 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 PFH38011.1 - 1.7e-14 52.5 15.1 4.8e-06 25.8 0.0 4.7 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 PFH38011.1 - 2e-11 44.1 0.1 2.6e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PFH38011.1 - 2.2e-06 27.5 1.7 0.039 13.9 0.1 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 PFH38011.1 - 0.00043 20.6 0.2 1.1 9.7 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 PFH38011.1 - 0.0017 18.6 0.0 1.7 9.0 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3008 PF11450.8 PFH38011.1 - 0.0031 17.6 1.6 0.0047 17.1 0.3 2.0 2 0 0 2 2 2 1 Protein of unknwon function (DUF3008) HTH_40 PF14493.6 PFH38011.1 - 0.0035 17.8 0.0 0.036 14.5 0.0 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain Caleosin PF05042.13 PFH38011.1 - 0.0044 17.0 0.2 0.96 9.4 0.0 2.9 2 1 1 3 3 3 1 Caleosin related protein Dockerin_1 PF00404.18 PFH38011.1 - 0.031 14.5 0.1 0.74 10.1 0.0 2.4 2 0 0 2 2 2 0 Dockerin type I domain Peptidase_M24 PF00557.24 PFH38011.1 - 0.046 13.4 0.0 0.65 9.6 0.0 2.0 2 0 0 2 2 2 0 Metallopeptidase family M24 Skp1 PF01466.19 PFH38011.1 - 0.052 13.7 1.7 14 5.9 0.0 3.2 3 0 0 3 3 3 0 Skp1 family, dimerisation domain DUF1257 PF06868.11 PFH38011.1 - 0.082 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) IF2_N PF04760.15 PFH38011.1 - 0.17 11.8 1.6 24 4.9 0.1 3.2 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Slx4 PF09494.10 PFH38011.1 - 0.17 11.8 0.2 7.9 6.5 0.0 3.1 3 1 0 3 3 3 0 Slx4 endonuclease Smoothelin PF12510.8 PFH38011.1 - 0.5 10.4 3.6 0.38 10.8 0.8 2.2 3 0 0 3 3 3 0 Smoothelin cytoskeleton protein DDRGK PF09756.9 PFH38012.1 - 2.4e-52 177.3 22.6 6.2e-52 175.9 22.6 1.7 1 0 0 1 1 1 1 DDRGK domain CDC27 PF09507.10 PFH38012.1 - 0.02 14.3 20.8 0.035 13.5 20.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 JSRP PF15312.6 PFH38012.1 - 0.1 12.5 1.0 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Borrelia_P83 PF05262.11 PFH38012.1 - 6.4 5.1 16.3 8.9 4.7 16.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 PFH38012.1 - 7.6 5.2 13.7 13 4.4 13.7 1.3 1 0 0 1 1 1 0 Presenilin CPBP PF02517.16 PFH38013.1 - 5.9e-10 39.4 0.1 1.4e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease AP2 PF00847.20 PFH38015.1 - 7.8e-06 26.0 0.3 1.8e-05 24.9 0.3 1.7 1 0 0 1 1 1 1 AP2 domain TFIIS_C PF01096.18 PFH38016.1 - 1.4e-15 56.8 2.5 1.4e-15 56.8 2.5 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) YliH PF10799.8 PFH38016.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) Zn-ribbon_8 PF09723.10 PFH38016.1 - 2 8.6 17.3 0.63 10.2 0.2 4.2 2 2 1 4 4 4 0 Zinc ribbon domain DZR PF12773.7 PFH38016.1 - 2.7 8.1 13.2 8 6.6 2.7 3.3 2 2 1 3 3 3 0 Double zinc ribbon Baculo_LEF5_C PF11792.8 PFH38016.1 - 3.3 7.4 9.6 0.22 11.2 3.5 2.2 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain DUF951 PF06107.11 PFH38016.1 - 9.2 6.3 8.3 78 3.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF951) MCR_gamma PF02240.16 PFH38018.1 - 0.081 12.2 0.2 0.78 8.9 0.0 1.9 1 1 1 2 2 2 0 Methyl-coenzyme M reductase gamma subunit EAR PF07897.11 PFH38019.1 - 2.5 7.8 5.3 3.8 7.2 0.1 3.1 3 0 0 3 3 3 0 Ethylene-responsive binding factor-associated repression Sad1_UNC PF07738.13 PFH38020.1 - 2.8e-22 79.1 0.0 2.2e-10 40.6 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal PTRF_SDPR PF15237.6 PFH38020.1 - 0.014 15.1 1.0 0.014 15.1 1.0 2.9 2 1 1 3 3 3 0 PTRF/SDPR family PCAF_N PF06466.11 PFH38020.1 - 0.066 12.8 1.2 0.1 12.1 1.2 1.2 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain DUF4611 PF15387.6 PFH38020.1 - 0.8 10.0 16.3 1.2 9.5 4.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Exonuc_VII_L PF02601.15 PFH38020.1 - 4.1 6.9 11.2 7.1 6.1 11.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 PFH38020.1 - 6.2 5.8 12.9 12 4.9 12.5 1.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2570 PF10828.8 PFH38020.1 - 9.7 6.1 7.8 6.3 6.7 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DUF4407 PF14362.6 PFH38021.1 - 0.0034 16.8 3.2 0.0034 16.8 3.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) DUF4131 PF13567.6 PFH38021.1 - 0.035 13.8 0.1 0.08 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) FlxA PF14282.6 PFH38021.1 - 0.18 11.8 0.6 0.65 10.0 0.3 2.1 2 0 0 2 2 2 0 FlxA-like protein ApoLp-III PF07464.11 PFH38021.1 - 0.24 11.5 2.9 0.68 10.0 0.2 2.6 1 1 3 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 PFH38021.1 - 0.34 8.8 5.6 0.51 8.2 5.6 1.2 1 0 0 1 1 1 0 Prominin Uso1_p115_C PF04871.13 PFH38021.1 - 0.44 10.9 5.3 16 5.9 1.3 2.7 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Sec34 PF04136.15 PFH38021.1 - 0.71 9.8 6.0 0.11 12.4 1.4 2.0 2 1 0 2 2 2 0 Sec34-like family DUF16 PF01519.16 PFH38021.1 - 0.92 10.0 7.3 0.083 13.4 0.9 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 Prefoldin_2 PF01920.20 PFH38021.1 - 2.9 7.9 7.7 0.31 11.0 1.7 2.5 2 0 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.12 PFH38021.1 - 2.9 8.0 6.4 1.4 9.0 0.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 PFH38021.1 - 3 8.1 15.8 0.062 13.5 3.9 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 PFH38021.1 - 4.2 7.4 12.5 2.8 8.0 1.7 3.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 PFH38021.1 - 5.1 7.1 8.7 0.17 11.9 0.6 2.5 2 1 0 3 3 3 0 Laminin Domain II V-SNARE PF05008.15 PFH38021.1 - 5.5 7.5 7.9 0.86 10.0 1.2 3.0 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus TMPIT PF07851.13 PFH38021.1 - 6.2 6.0 5.2 2.6 7.2 0.1 2.3 2 0 0 2 2 2 0 TMPIT-like protein DivIC PF04977.15 PFH38021.1 - 7.6 6.4 8.2 2.6 7.9 0.1 3.9 3 1 1 4 4 4 0 Septum formation initiator LRR_9 PF14580.6 PFH38023.1 - 2e-10 40.4 0.1 3.7e-10 39.6 0.1 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 PFH38023.1 - 8.1e-09 35.6 2.0 0.00026 21.3 0.6 3.9 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH38023.1 - 2.8e-06 27.0 1.1 2.8e-06 27.0 1.1 2.7 3 1 0 3 3 3 1 Leucine rich repeat PH PF00169.29 PFH38024.1 - 7.2e-06 26.5 1.0 1.7e-05 25.3 0.2 1.9 1 1 1 2 2 2 1 PH domain PH_16 PF17838.1 PFH38024.1 - 0.00042 20.2 0.0 0.00058 19.7 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_TFIIH PF08567.11 PFH38024.1 - 0.049 14.0 0.3 0.099 13.0 0.3 1.5 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Ig_4 PF16680.5 PFH38024.1 - 0.062 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Ax_dynein_light PF10211.9 PFH38025.1 - 2.2e-73 246.2 15.0 2.6e-73 246.0 15.0 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Tropomyosin_1 PF12718.7 PFH38025.1 - 0.00034 20.8 11.1 0.00034 20.8 11.1 1.5 2 0 0 2 2 2 1 Tropomyosin like Nsp1_C PF05064.13 PFH38025.1 - 0.024 14.5 7.5 0.024 14.5 7.5 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region TRAF_BIRC3_bd PF16673.5 PFH38025.1 - 0.27 11.1 6.7 0.73 9.7 6.7 1.7 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Acetyltransf_11 PF13720.6 PFH38025.1 - 0.92 10.0 3.6 0.98 9.9 0.3 2.3 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Exonuc_VII_L PF02601.15 PFH38025.1 - 1.6 8.2 11.0 2.1 7.8 11.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Enkurin PF13864.6 PFH38025.1 - 2.3 8.7 15.9 4.2 7.9 3.2 2.5 1 1 1 2 2 2 0 Calmodulin-binding Fungal_TACC PF12709.7 PFH38025.1 - 2.9 8.4 12.9 0.79 10.2 9.1 2.1 2 2 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Uso1_p115_C PF04871.13 PFH38025.1 - 3.2 8.2 15.9 2.8 8.3 13.8 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Prefoldin PF02996.17 PFH38025.1 - 3.3 7.7 11.7 2.8 7.9 4.2 2.6 1 1 1 2 2 2 0 Prefoldin subunit Ribosomal_L28e PF01778.17 PFH38026.1 - 3.7e-30 105.0 3.1 3.7e-30 105.0 3.1 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 PFH38026.1 - 2.7e-17 63.2 35.0 2.7e-17 63.2 35.0 3.2 2 1 1 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.10 PFH38026.1 - 4.8e-05 22.9 29.9 7.3e-05 22.3 29.9 1.2 1 0 0 1 1 1 1 BUD22 DUF2151 PF10221.9 PFH38026.1 - 0.02 13.5 18.4 0.03 12.9 18.4 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator CDC27 PF09507.10 PFH38026.1 - 0.66 9.3 30.1 1 8.7 30.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 JUPITER PF17054.5 PFH38028.1 - 0.00071 19.1 1.2 0.043 13.3 0.2 2.1 2 0 0 2 2 2 2 Microtubule-Associated protein Jupiter TP_methylase PF00590.20 PFH38030.1 - 1.8e-23 83.6 0.0 4.3e-23 82.4 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pam16 PF03656.13 PFH38031.1 - 1.5e-11 44.4 0.3 1.8e-11 44.2 0.3 1.1 1 0 0 1 1 1 1 Pam16 Mito_carr PF00153.27 PFH38032.1 - 2.3e-70 232.6 3.6 7.3e-24 83.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cyclin_N PF00134.23 PFH38034.1 - 7e-05 22.6 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain C2 PF00168.30 PFH38035.1 - 8.1e-21 74.2 0.2 1.5e-20 73.4 0.2 1.4 1 0 0 1 1 1 1 C2 domain TruB_C PF09142.11 PFH38035.1 - 0.0036 17.0 0.2 0.0081 15.9 0.2 1.6 1 0 0 1 1 1 1 tRNA Pseudouridine synthase II, C terminal HALZ PF02183.18 PFH38036.1 - 0.01 16.1 17.8 1.4 9.2 0.2 5.4 5 1 0 5 5 5 0 Homeobox associated leucine zipper Filament PF00038.21 PFH38036.1 - 0.51 9.9 70.9 0.07 12.7 11.8 4.4 2 1 2 4 4 4 0 Intermediate filament protein Baculo_PEP_C PF04513.12 PFH38036.1 - 6 6.9 25.4 0.11 12.6 0.9 3.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus 2TM PF13239.6 PFH38037.1 - 0.096 13.0 0.0 0.096 13.0 0.0 3.6 3 1 0 3 3 3 0 2TM domain AAA_6 PF12774.7 PFH38038.1 - 1.8e-149 497.1 0.6 2.7e-147 490.0 0.0 3.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PFH38038.1 - 3.3e-122 408.4 4.3 3.3e-122 408.4 4.3 3.0 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PFH38038.1 - 2.4e-104 348.8 0.0 7.5e-102 340.7 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 PFH38038.1 - 1.7e-92 309.4 0.4 1e-91 306.8 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 PFH38038.1 - 2.3e-83 278.7 0.4 2.3e-83 278.7 0.4 2.8 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 PFH38038.1 - 8.2e-78 260.1 0.1 1.2e-73 246.5 0.0 3.8 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PFH38038.1 - 2.1e-53 180.5 0.1 9.7e-53 178.3 0.0 2.3 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PFH38038.1 - 5.2e-49 165.3 0.2 7.4e-46 155.1 0.0 3.4 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 PFH38038.1 - 7.3e-39 133.7 5.1 1.5e-38 132.7 5.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 PFH38038.1 - 1e-31 109.7 0.0 4.1e-31 107.8 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PFH38038.1 - 2.2e-21 76.3 0.0 1.9e-05 24.7 0.0 6.7 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PFH38038.1 - 2e-16 60.0 0.0 8.5e-16 58.0 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 PFH38038.1 - 1.8e-09 38.1 0.1 0.12 12.8 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PFH38038.1 - 1.1e-07 32.2 0.8 0.25 11.6 0.0 5.4 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.6 PFH38038.1 - 2.3e-05 24.9 0.1 0.12 12.9 0.0 4.3 4 0 0 4 4 3 1 AAA domain DUF853 PF05872.12 PFH38038.1 - 5.2e-05 22.0 1.9 0.99 7.9 0.0 3.5 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) AAA_16 PF13191.6 PFH38038.1 - 0.00018 21.9 8.4 1.4 9.3 0.0 5.6 6 0 0 6 6 3 1 AAA ATPase domain Sigma54_activat PF00158.26 PFH38038.1 - 0.00038 20.2 0.3 4.3 7.0 0.0 3.6 3 0 0 3 3 3 1 Sigma-54 interaction domain T2SSE PF00437.20 PFH38038.1 - 0.001 18.2 0.2 0.02 13.9 0.0 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein RNA_helicase PF00910.22 PFH38038.1 - 0.0022 18.4 0.0 1.2 9.6 0.0 3.6 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 PFH38038.1 - 0.0078 15.9 8.3 3.8 7.2 0.1 4.3 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 PFH38038.1 - 0.015 14.7 1.3 0.89 8.9 0.0 3.7 5 0 0 5 5 3 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 PFH38038.1 - 0.021 14.2 0.3 0.61 9.4 0.0 3.1 3 0 0 3 3 3 0 KaiC FtsK_SpoIIIE PF01580.18 PFH38038.1 - 0.022 14.1 0.0 0.079 12.3 0.0 1.9 1 0 0 1 1 1 0 FtsK/SpoIIIE family ResIII PF04851.15 PFH38038.1 - 0.056 13.5 0.5 9.3 6.2 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 PFH38038.1 - 0.062 12.9 1.2 67 3.0 0.1 4.3 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.6 PFH38038.1 - 0.077 13.2 1.3 55 3.9 0.0 4.9 4 0 0 4 4 4 0 AAA domain DEAD PF00270.29 PFH38038.1 - 0.11 12.2 0.0 6.2 6.6 0.0 3.1 3 0 0 3 3 2 0 DEAD/DEAH box helicase Halogen_Hydrol PF10112.9 PFH38038.1 - 0.13 12.3 7.3 0.81 9.7 0.8 3.7 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein AAA_19 PF13245.6 PFH38038.1 - 0.15 12.4 5.7 57 4.0 0.2 4.8 5 0 0 5 5 4 0 AAA domain PhoH PF02562.16 PFH38038.1 - 0.21 11.0 1.9 16 4.9 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein SRP54 PF00448.22 PFH38038.1 - 0.27 10.8 3.2 23 4.5 0.4 4.2 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain PolyA_pol PF01743.20 PFH38038.1 - 0.64 10.5 2.4 2.6 8.5 2.4 2.0 1 0 0 1 1 1 0 Poly A polymerase head domain bZIP_1 PF00170.21 PFH38038.1 - 1 9.5 5.1 6 7.0 5.1 2.5 1 0 0 1 1 1 0 bZIP transcription factor AAA_28 PF13521.6 PFH38038.1 - 1.7 8.9 3.9 39 4.4 0.0 4.0 4 0 0 4 4 3 0 AAA domain ABC_membrane PF00664.23 PFH38039.1 - 4.5e-33 115.1 1.8 8.8e-33 114.1 1.8 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PFH38039.1 - 1.3e-30 106.7 0.0 4e-30 105.1 0.0 1.8 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PFH38039.1 - 6.3e-06 25.8 0.0 0.00079 18.9 0.0 2.7 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PFH38039.1 - 0.0014 19.0 1.5 0.0089 16.4 1.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PFH38039.1 - 0.0015 18.8 0.0 0.065 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PFH38039.1 - 0.0019 17.5 0.0 0.004 16.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 PFH38039.1 - 0.0085 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 PFH38039.1 - 0.011 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 PFH38039.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase CoA_transf_3 PF02515.17 PFH38039.1 - 0.06 12.5 0.2 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 CoA-transferase family III AAA_30 PF13604.6 PFH38039.1 - 0.13 12.0 0.0 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 PFH38039.1 - 0.18 10.5 0.0 6.6 5.4 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 PFH38039.1 - 0.2 11.8 0.0 0.49 10.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 PFH38039.1 - 0.24 11.3 0.0 6.3 6.7 0.0 2.2 2 0 0 2 2 2 0 NTPase Sec63 PF02889.16 PFH38040.1 - 2.2e-106 354.7 0.0 3.9e-63 213.0 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 PFH38040.1 - 6.8e-51 172.5 0.0 5e-24 85.0 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 PFH38040.1 - 9.3e-24 84.3 0.0 1.8e-12 47.6 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PFH38040.1 - 1.7e-14 54.1 0.0 8.8e-07 29.3 0.0 3.2 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 PFH38040.1 - 4.4e-09 36.7 0.0 0.0027 18.0 0.0 3.8 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 PFH38040.1 - 5.5e-06 26.8 0.6 0.018 15.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 PFH38040.1 - 0.00027 21.4 0.2 1.3 9.4 0.0 4.4 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 PFH38040.1 - 0.00044 19.4 0.0 0.38 9.8 0.0 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 PFH38040.1 - 0.0086 15.5 0.1 1.7 8.1 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein UvrD-helicase PF00580.21 PFH38040.1 - 0.034 13.7 0.8 6.4 6.2 0.0 2.8 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 PFH38040.1 - 0.23 11.2 1.9 4.6 6.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain Cytomega_UL84 PF06284.11 PFH38041.1 - 0.016 13.7 0.0 0.028 12.9 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Arm PF00514.23 PFH38041.1 - 0.24 11.5 4.4 0.68 10.1 0.1 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF1180 PF06679.12 PFH38041.1 - 3.3 8.1 12.9 11 6.4 0.0 4.7 3 1 2 5 5 5 0 Protein of unknown function (DUF1180) 2_5_RNA_ligase2 PF13563.6 PFH38043.1 - 1.2e-05 25.2 0.1 3.2e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily CPDase PF07823.11 PFH38043.1 - 0.0017 18.1 0.2 0.37 10.5 0.1 2.3 2 1 0 2 2 2 2 Cyclic phosphodiesterase-like protein Bax1-I PF01027.20 PFH38044.1 - 3.1e-37 128.4 22.2 3.9e-37 128.1 22.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 PFH38044.1 - 0.00048 19.8 18.2 0.00068 19.3 18.2 1.2 1 0 0 1 1 1 1 Bax inhibitor 1 like RcnB PF11776.8 PFH38044.1 - 0.061 13.4 2.7 0.11 12.5 0.1 2.6 3 0 0 3 3 3 0 Nickel/cobalt transporter regulator VKOR PF07884.14 PFH38046.1 - 1.2e-22 80.4 10.6 1.5e-22 80.1 10.6 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family TMA7 PF09072.10 PFH38047.1 - 6.5e-08 33.3 15.3 1.2e-07 32.5 15.3 1.4 1 0 0 1 1 1 1 Translation machinery associated TMA7 DcuC PF03606.15 PFH38047.1 - 0.13 10.7 0.0 0.14 10.5 0.0 1.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF5134 PF17197.4 PFH38048.1 - 0.033 14.1 0.9 0.9 9.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) DUF2721 PF11026.8 PFH38048.1 - 0.56 10.1 4.9 0.28 11.1 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF1490 PF07371.12 PFH38049.1 - 0.12 12.4 0.5 0.32 11.1 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) ATP-synt_C PF00137.21 PFH38050.1 - 2.5e-07 30.9 7.8 2.5e-07 30.9 7.8 2.1 2 0 0 2 2 2 1 ATP synthase subunit C Mito_carr PF00153.27 PFH38052.1 - 2.7e-29 100.9 8.2 1.5e-11 44.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 PFH38052.1 - 0.062 13.4 0.1 0.062 13.4 0.1 2.7 2 1 0 2 2 2 0 Pre-toxin domain with VENN motif Paf1 PF03985.13 PFH38055.1 - 3.2e-09 36.3 21.0 1.1e-07 31.2 0.0 3.3 2 1 0 3 3 3 2 Paf1 Tub_N PF16322.5 PFH38055.1 - 0.09 13.2 16.9 0.31 11.4 16.9 2.0 1 0 0 1 1 1 0 Tubby N-terminal TFIIA PF03153.13 PFH38055.1 - 1.5 8.7 13.4 0.72 9.8 11.1 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Peptidase_C1 PF00112.23 PFH38056.1 - 7.7e-53 179.8 2.4 1e-52 179.4 2.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease DUF4667 PF15700.5 PFH38057.1 - 0.046 13.8 0.2 0.046 13.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) MHYT PF03707.16 PFH38057.1 - 0.9 9.8 3.8 1.1 9.5 0.4 2.6 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat YjeF_N PF03853.15 PFH38058.1 - 5e-41 140.4 0.0 6.5e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus GST_N_3 PF13417.6 PFH38059.1 - 2e-07 31.3 0.0 3.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PFH38059.1 - 0.00011 22.4 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 PFH38059.1 - 0.0042 17.3 0.1 0.0082 16.3 0.1 1.5 1 0 0 1 1 1 1 Glutaredoxin PAC4 PF16093.5 PFH38059.1 - 0.13 12.4 4.3 0.13 12.4 1.8 2.1 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 Hist_deacetyl PF00850.19 PFH38060.1 - 7e-77 258.9 0.0 4e-69 233.4 0.0 2.2 2 0 0 2 2 2 2 Histone deacetylase domain MIF4G_like_2 PF09090.11 PFH38061.1 - 1.7e-07 31.0 0.1 1.7e-07 31.0 0.1 2.9 3 1 0 3 3 3 1 MIF4G like MIF4G_like PF09088.11 PFH38061.1 - 0.0045 16.8 0.3 0.01 15.6 0.3 1.7 1 0 0 1 1 1 1 MIF4G like DUF5337 PF17272.2 PFH38062.1 - 0.44 10.4 0.1 0.44 10.4 0.1 2.1 3 0 0 3 3 3 0 Family of unknown function (DUF5337) Proteasome PF00227.26 PFH38063.1 - 1.3e-55 187.8 0.2 1.8e-55 187.4 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PFH38063.1 - 2.3e-12 46.3 0.0 4.2e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature MFS_1 PF07690.16 PFH38064.1 - 0.099 11.5 46.0 0.0033 16.4 34.8 3.3 2 1 1 3 3 3 0 Major Facilitator Superfamily RNA_pol_L PF01193.24 PFH38065.1 - 2.2e-08 33.4 0.0 1.1e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 PFH38065.1 - 1.3e-05 25.5 0.0 0.0019 18.5 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L_2 PF13656.6 PFH38065.1 - 0.0064 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain QRPTase_N PF02749.16 PFH38065.1 - 0.16 12.0 0.0 0.94 9.6 0.0 2.1 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Dynein_light PF01221.18 PFH38066.1 - 3.4e-24 85.0 0.3 3.6e-24 84.9 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DZR PF12773.7 PFH38067.1 - 0.00016 21.6 3.3 0.00016 21.6 3.3 3.7 3 1 2 5 5 5 2 Double zinc ribbon zinc_ribbon_2 PF13240.6 PFH38067.1 - 0.34 10.7 3.9 14 5.6 0.1 3.0 2 0 0 2 2 2 0 zinc-ribbon domain Cytochrom_c3_2 PF14537.6 PFH38067.1 - 9.9 6.7 6.9 2.1 8.9 1.4 2.8 3 1 0 3 3 3 0 Cytochrome c3 CRM1_C PF08767.11 PFH38070.1 - 3.9e-108 361.4 5.8 3.9e-108 361.4 5.8 3.2 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 PFH38070.1 - 2.2e-37 128.4 2.6 2.2e-37 128.4 2.6 3.8 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 PFH38070.1 - 1.8e-21 76.0 1.1 8.8e-21 73.8 0.0 2.7 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat_2 PF18784.1 PFH38070.1 - 2.2e-19 68.8 4.5 5.7e-18 64.3 1.0 3.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 IBN_N PF03810.19 PFH38070.1 - 6.1e-11 42.1 0.1 2e-10 40.5 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 PFH38070.1 - 0.0017 17.8 0.0 0.0039 16.7 0.0 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat DUF3945 PF13101.6 PFH38070.1 - 0.14 11.9 0.0 3.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) DUF1331 PF07048.11 PFH38071.1 - 0.094 12.4 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) TPR_1 PF00515.28 PFH38074.1 - 1.7e-13 49.7 10.1 0.00027 20.6 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PFH38074.1 - 7.8e-10 38.1 10.7 0.031 14.4 0.1 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 PFH38074.1 - 1.5e-07 31.1 3.4 0.045 14.0 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 PFH38074.1 - 2.3e-05 24.5 1.8 2.3e-05 24.5 1.8 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 PFH38074.1 - 0.008 15.8 1.9 0.084 12.6 0.4 3.1 2 1 1 3 3 3 1 TPR repeat TPR_12 PF13424.6 PFH38074.1 - 0.035 14.4 12.5 1 9.7 0.2 4.5 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 PFH38074.1 - 0.08 13.0 3.4 11 6.3 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT_EZ PF13513.6 PFH38074.1 - 0.12 12.9 0.2 0.12 12.9 0.2 7.3 7 1 0 7 7 7 0 HEAT-like repeat TPR_6 PF13174.6 PFH38074.1 - 0.19 12.4 10.6 3.9 8.3 0.2 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PFH38074.1 - 2.9 8.0 6.1 0.61 10.2 0.1 2.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Pkinase PF00069.25 PFH38075.1 - 0.00019 20.9 0.1 0.014 14.7 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 PFH38075.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like WD40 PF00400.32 PFH38076.1 - 2.3e-16 59.9 10.0 0.0086 16.9 0.0 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat ELFV_dehydrog PF00208.21 PFH38081.1 - 7.4e-49 166.7 0.0 1.3e-48 165.8 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 PFH38081.1 - 6.8e-24 83.6 0.0 6.7e-19 67.0 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 PFH38081.1 - 8.7e-05 22.4 0.0 0.001 19.0 0.0 2.4 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Trigger_C PF05698.14 PFH38081.1 - 0.12 12.4 0.1 5.4 7.0 0.1 2.6 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus DHHC PF01529.20 PFH38082.1 - 5.5e-30 104.2 6.1 5.5e-30 104.2 6.1 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase SUI1 PF01253.22 PFH38083.1 - 7.2e-23 80.9 0.4 9.8e-23 80.5 0.4 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF3395 PF11875.8 PFH38083.1 - 0.11 12.3 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) IFT46_B_C PF12317.8 PFH38084.1 - 1.9e-40 138.9 0.0 2.5e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal RED_N PF07808.13 PFH38085.1 - 1e-30 107.0 10.8 3.3e-30 105.4 6.8 3.1 2 1 0 2 2 2 1 RED-like protein N-terminal region RED_C PF07807.11 PFH38085.1 - 2e-16 60.4 3.5 2e-16 60.4 3.5 3.4 3 1 0 3 3 3 1 RED-like protein C-terminal region baeRF_family12 PF18856.1 PFH38085.1 - 5.3 7.6 15.2 0.53 10.9 8.1 2.9 2 1 1 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 12 Hydrolase_4 PF12146.8 PFH38086.1 - 3.9e-08 32.9 0.1 4.3e-06 26.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 PFH38086.1 - 5.8e-08 32.7 0.0 2.9e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 PFH38086.1 - 0.00012 21.8 0.0 0.0006 19.5 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PFH38086.1 - 0.00064 20.4 1.5 0.0008 20.1 0.2 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 PFH38086.1 - 0.0094 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PFH38086.1 - 0.018 14.5 0.0 0.056 12.9 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Rad10 PF03834.14 PFH38088.1 - 1.3e-29 102.5 0.0 1.1e-28 99.5 0.0 2.0 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 PFH38088.1 - 8.1e-08 32.8 0.3 1.4e-07 32.0 0.3 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 PFH38088.1 - 5.8e-05 22.8 0.1 0.00012 21.7 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 PFH38088.1 - 0.036 14.1 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_3 PF12836.7 PFH38088.1 - 0.088 13.1 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ssl1 PF04056.14 PFH38089.1 - 0.068 13.0 0.0 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 Ssl1-like DUF3446 PF11928.8 PFH38089.1 - 4.1 7.8 8.9 3.3 8.1 4.5 2.1 1 1 1 2 2 2 0 Early growth response N-terminal domain Flavodoxin_1 PF00258.25 PFH38090.1 - 5e-25 88.4 0.1 9.6e-22 77.7 0.0 2.5 2 0 0 2 2 2 2 Flavodoxin FAD_binding_1 PF00667.20 PFH38090.1 - 2.5e-09 37.0 0.1 7.9e-08 32.1 0.0 2.9 2 1 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 PFH38090.1 - 0.0021 18.7 0.0 0.037 14.7 0.0 2.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain UPF0172 PF03665.13 PFH38091.1 - 2.9e-28 99.2 0.0 8.8e-17 61.8 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0172) JAB PF01398.21 PFH38091.1 - 0.0045 16.9 0.0 2.9 7.9 0.0 2.4 2 0 0 2 2 2 2 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TM231 PF10149.9 PFH38092.1 - 1.9e-21 76.7 1.6 4.3e-12 46.0 0.0 2.4 2 1 0 2 2 2 2 Transmembrane protein 231 Peptidase_S9 PF00326.21 PFH38093.1 - 0.013 14.9 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PFH38093.1 - 0.022 14.0 0.1 0.36 10.0 0.0 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Phage_holin_3_6 PF07332.11 PFH38093.1 - 0.53 10.3 5.3 0.92 9.6 5.3 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PIH1 PF08190.12 PFH38094.1 - 5.5e-22 78.0 0.0 1.4e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 PFH38094.1 - 6.1e-09 36.2 0.0 2.3e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 PIH1 CS-like domain Thioredoxin PF00085.20 PFH38095.1 - 9.7e-56 186.1 0.2 5.6e-32 109.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 PFH38095.1 - 3.4e-12 46.6 0.1 4.9e-06 26.6 0.0 2.8 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PFH38095.1 - 7.7e-09 35.6 0.1 0.001 19.2 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 PFH38095.1 - 1.4e-07 31.9 2.1 0.0053 17.2 0.1 4.0 2 2 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 PFH38095.1 - 1.6e-07 31.0 0.1 0.00031 20.2 0.0 3.0 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PFH38095.1 - 3.5e-07 30.4 0.0 0.0038 17.5 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_3 PF13192.6 PFH38095.1 - 6.3e-07 29.3 0.0 0.047 13.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.21 PFH38095.1 - 4.7e-06 26.5 0.4 0.023 14.6 0.0 2.8 3 1 1 4 4 4 2 AhpC/TSA family Thioredoxin_9 PF14595.6 PFH38095.1 - 0.00014 21.6 0.0 0.25 11.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_4 PF13462.6 PFH38095.1 - 0.0017 18.5 0.1 2.4 8.3 0.0 2.6 2 1 0 2 2 2 2 Thioredoxin TraF PF13728.6 PFH38095.1 - 0.0021 17.9 0.0 0.54 10.0 0.0 2.5 2 0 0 2 2 2 1 F plasmid transfer operon protein Redoxin PF08534.10 PFH38095.1 - 0.0029 17.3 0.5 0.27 11.0 0.0 2.7 3 0 0 3 3 3 1 Redoxin Pkinase PF00069.25 PFH38096.1 - 5.2e-54 183.4 0.0 1.8e-49 168.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH38096.1 - 2.9e-20 72.6 0.0 1.8e-18 66.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PFH38096.1 - 0.0011 18.3 0.0 0.0028 17.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 PFH38096.1 - 0.16 10.9 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L35Ae PF01247.18 PFH38097.1 - 1.6e-42 143.6 0.1 1.8e-42 143.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 PFH38097.1 - 0.00062 19.9 0.0 0.74 10.1 0.0 2.4 2 1 0 2 2 2 2 RimM N-terminal domain EF-hand_1 PF00036.32 PFH38098.1 - 7.3e-42 137.8 11.9 1.7e-10 39.6 1.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PFH38098.1 - 8.6e-36 122.2 2.9 4.2e-18 65.6 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PFH38098.1 - 4.7e-31 106.4 11.1 8.8e-15 54.3 0.8 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 PFH38098.1 - 5.9e-31 103.7 6.3 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PFH38098.1 - 1.4e-27 93.9 9.2 2.3e-06 26.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 PFH38098.1 - 2.8e-16 59.6 0.2 3.3e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PFH38098.1 - 1.8e-09 37.5 0.5 0.00028 20.8 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PFH38098.1 - 3.6e-08 33.7 0.0 0.0039 17.5 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 PFH38098.1 - 1.5e-06 29.0 0.0 0.00058 20.7 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 PFH38098.1 - 2.1e-05 24.5 0.0 0.042 13.9 0.0 3.0 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 PFH38098.1 - 5.7e-05 23.2 3.8 0.016 15.4 0.4 2.9 1 1 2 3 3 3 2 Dockerin type I domain EFhand_Ca_insen PF08726.10 PFH38098.1 - 0.00015 21.8 1.3 0.00064 19.8 0.2 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.13 PFH38098.1 - 0.00024 21.1 0.5 0.16 11.9 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 PFH38098.1 - 0.00058 20.6 0.6 1.3 9.9 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 PFH38098.1 - 0.0012 18.8 0.8 0.46 10.4 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 PFH38098.1 - 0.0024 18.2 0.2 1.6 9.1 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF1103 PF06513.11 PFH38098.1 - 0.0045 16.6 1.5 0.0052 16.4 1.5 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) YqeY PF09424.10 PFH38098.1 - 0.0093 16.0 0.3 0.13 12.4 0.1 2.0 1 1 0 2 2 2 1 Yqey-like protein MotA_activ PF09114.10 PFH38098.1 - 0.011 15.9 0.3 0.22 11.7 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.16 PFH38098.1 - 0.014 15.6 0.1 4.8 7.5 0.0 3.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 PFH38098.1 - 0.015 15.2 0.5 0.79 9.6 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 PFH38098.1 - 0.027 13.0 0.0 0.027 13.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 PFH38098.1 - 0.053 13.9 0.1 12 6.3 0.0 2.4 1 1 0 2 2 2 0 EF-hand domain Fe_hyd_lg_C PF02906.14 PFH38098.1 - 0.055 13.1 0.5 0.14 11.8 0.5 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain dCache_2 PF08269.11 PFH38098.1 - 0.06 12.5 0.0 4.7 6.3 0.0 2.1 1 1 1 2 2 2 0 Cache domain DUF853 PF05872.12 PFH38098.1 - 0.068 11.8 0.1 2 6.9 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) SUB1_ProdP9 PF18213.1 PFH38098.1 - 0.12 12.2 2.6 6.4 6.7 0.1 3.0 1 1 1 3 3 3 0 SUB1 protease Prodomain ProdP9 SapB_1 PF05184.15 PFH38098.1 - 0.17 11.9 3.3 25 5.0 0.1 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 Ctr PF04145.15 PFH38101.1 - 5.1e-14 53.1 13.6 2.1e-07 31.7 9.7 2.6 1 1 0 2 2 2 2 Ctr copper transporter family DUF3561 PF12084.8 PFH38101.1 - 0.37 10.8 8.9 0.31 11.1 4.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) Thymidylat_synt PF00303.19 PFH38103.1 - 1.4e-110 368.7 0.0 1.8e-110 368.3 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 PFH38103.1 - 6.2e-26 91.0 0.0 1.8e-18 66.8 0.0 2.5 2 0 0 2 2 2 2 Dihydrofolate reductase RibD_C PF01872.17 PFH38103.1 - 0.14 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 RibD C-terminal domain Ras PF00071.22 PFH38104.1 - 2.3e-52 176.8 0.3 3.1e-52 176.4 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH38104.1 - 1.6e-30 105.8 0.2 2.4e-30 105.2 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Kelch_4 PF13418.6 PFH38104.1 - 3.7e-25 87.7 0.1 1.3e-06 28.3 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PFH38104.1 - 3.8e-22 77.8 0.6 5.7e-05 23.0 0.0 6.8 6 1 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 PFH38104.1 - 2.1e-20 72.5 0.6 0.015 15.6 0.0 7.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 PFH38104.1 - 5.5e-16 58.2 0.1 2.2e-05 24.5 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Arf PF00025.21 PFH38104.1 - 3.1e-12 46.3 0.0 4.9e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Kelch_2 PF07646.15 PFH38104.1 - 9.7e-12 44.4 0.0 0.17 11.9 0.0 6.2 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 PFH38104.1 - 3.9e-06 26.3 0.0 0.22 11.1 0.0 5.5 6 0 0 6 6 6 1 Kelch motif Gtr1_RagA PF04670.12 PFH38104.1 - 0.00036 20.0 0.1 0.0005 19.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PFH38104.1 - 0.00037 20.6 0.0 0.00063 19.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PFH38104.1 - 0.0035 16.9 0.0 0.0078 15.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PFH38104.1 - 0.074 13.0 0.0 0.99 9.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NanE PF04131.14 PFH38104.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase UAA PF08449.11 PFH38105.1 - 1.1e-07 31.4 0.0 1.1e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.16 PFH38105.1 - 0.011 15.1 0.6 0.089 12.1 0.0 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family EamA PF00892.20 PFH38105.1 - 0.065 13.4 17.2 0.33 11.1 0.2 3.5 3 0 0 3 3 3 0 EamA-like transporter family PAN_1 PF00024.26 PFH38106.1 - 9e-24 83.2 12.6 1e-05 25.4 0.2 5.0 3 1 1 4 4 4 4 PAN domain PAN_4 PF14295.6 PFH38106.1 - 2.4e-20 72.2 15.6 7.4e-06 25.8 1.6 4.7 4 0 0 4 4 4 4 PAN domain Exo_endo_phos PF03372.23 PFH38107.1 - 0.00019 21.0 0.0 0.0095 15.5 0.0 2.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 PFH38108.1 - 6.9e-24 84.6 0.0 1.5e-23 83.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH38108.1 - 1.3e-07 31.2 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH38108.1 - 1.3e-07 31.2 0.0 5.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 PFH38108.1 - 0.00033 20.3 0.0 0.00073 19.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 PFH38108.1 - 0.0023 17.9 0.0 0.0083 16.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PFH38108.1 - 0.0025 17.2 0.0 0.006 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 PFH38108.1 - 0.21 10.4 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Seadorna_VP7 PF07387.11 PFH38108.1 - 0.27 10.2 0.0 0.42 9.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 PFH38110.1 - 3e-24 85.8 0.0 8e-24 84.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PFH38110.1 - 2.9e-07 30.1 0.0 7.5e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_Tyr PF07714.17 PFH38110.1 - 2.1e-05 23.9 0.0 3.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH38110.1 - 0.00018 21.6 0.0 0.00047 20.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 PFH38110.1 - 0.00026 20.7 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 PFH38110.1 - 0.0032 16.9 0.0 0.0078 15.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinesin PF00225.23 PFH38111.1 - 9.7e-84 281.1 0.2 4.6e-83 278.9 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PFH38111.1 - 2.6e-18 66.4 0.0 1.2e-15 57.7 0.0 2.9 3 0 0 3 3 3 2 Microtubule binding CAGE1 PF15066.6 PFH38111.1 - 1.3 7.7 6.4 1.9 7.1 6.4 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family GrpE PF01025.19 PFH38111.1 - 4.6 6.9 6.0 7.8 6.1 6.0 1.2 1 0 0 1 1 1 0 GrpE UPF0242 PF06785.11 PFH38111.1 - 9.1 6.3 9.1 16 5.6 9.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Methyltransf_31 PF13847.6 PFH38112.1 - 5.1e-08 32.9 0.0 1.3e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH38112.1 - 7.1e-08 33.1 0.1 2e-07 31.6 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PFH38112.1 - 5.6e-07 29.5 0.0 1.3e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PFH38112.1 - 7.8e-06 26.5 0.2 2.3e-05 25.0 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH38112.1 - 0.00015 22.4 0.2 0.00083 20.1 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 PFH38112.1 - 0.00043 19.9 0.0 0.00089 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 PFH38112.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PrmA PF06325.13 PFH38112.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RCC1 PF00415.18 PFH38113.1 - 1.7e-65 217.4 36.9 3.6e-13 49.9 0.1 9.5 8 2 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH38113.1 - 9.3e-33 111.4 53.4 1.6e-11 43.7 1.9 8.3 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 PFH38113.1 - 3.9e-05 23.5 0.8 5.8 6.6 0.0 4.4 3 1 0 4 4 4 3 TUP1-like enhancer of split DUF1921 PF09081.10 PFH38113.1 - 0.52 10.6 4.8 68 3.8 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF1921) Kelch_5 PF13854.6 PFH38113.1 - 3.1 7.9 5.9 69 3.6 0.1 4.1 4 0 0 4 4 4 0 Kelch motif Nudc_N PF14050.6 PFH38114.1 - 5.9e-22 77.4 0.0 9.7e-22 76.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 PFH38114.1 - 2.2e-08 35.0 0.0 5e-08 33.9 0.0 1.6 2 0 0 2 2 2 1 CS domain LRR_9 PF14580.6 PFH38115.1 - 2e-16 60.0 0.1 1.7e-06 27.6 0.2 3.2 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 PFH38115.1 - 3e-15 56.1 4.3 0.00055 20.3 0.4 4.6 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH38115.1 - 7e-10 38.5 4.6 0.00012 21.8 0.4 4.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 PFH38115.1 - 0.00019 21.2 1.2 0.69 10.1 0.1 3.1 2 0 0 2 2 2 2 Leucine Rich repeat LRR_1 PF00560.33 PFH38115.1 - 5.5 7.9 9.1 17 6.4 0.4 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat IHO1 PF15771.5 PFH38116.1 - 1.1 7.9 4.6 1.5 7.5 4.6 1.1 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 PROL5-SMR PF15621.6 PFH38116.1 - 1.9 9.1 14.6 0.55 10.8 1.1 2.4 2 1 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Methyltransf_11 PF08241.12 PFH38117.1 - 6.1e-11 42.8 0.4 6.5e-09 36.3 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH38117.1 - 3.8e-10 40.3 0.1 2.9e-07 31.1 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 PFH38117.1 - 1.4e-05 25.0 0.0 4.9e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH38117.1 - 2.6e-05 24.9 0.0 0.0013 19.4 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PFH38117.1 - 0.06 13.1 0.1 15 5.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Mito_carr PF00153.27 PFH38118.1 - 2.8e-55 184.2 4.3 3.5e-19 68.5 0.1 4.4 3 2 0 3 3 3 3 Mitochondrial carrier protein zf-CCHC_3 PF13917.6 PFH38119.1 - 2.3e-18 65.9 3.8 7e-18 64.3 3.8 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 PFH38119.1 - 1.1 9.4 3.0 2.2 8.5 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle WDCP PF15390.6 PFH38119.1 - 4.4 5.6 7.9 6.2 5.1 7.9 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Pheromone PF08015.11 PFH38119.1 - 7.5 7.7 21.7 0.89 10.6 16.0 2.5 2 0 0 2 2 2 0 Fungal mating-type pheromone Period_C PF12114.8 PFH38119.1 - 8.5 5.9 30.5 22 4.6 30.5 1.7 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Actin PF00022.19 PFH38121.1 - 1.4e-53 182.0 0.0 2.1e-23 82.6 0.0 3.2 3 0 0 3 3 3 3 Actin Ras PF00071.22 PFH38122.1 - 9.4e-58 194.4 0.0 1.1e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH38122.1 - 1.6e-33 115.5 0.0 2.7e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH38122.1 - 9.5e-12 44.7 0.0 1.2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PFH38122.1 - 6.1e-08 32.7 0.0 9.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PFH38122.1 - 1.3e-05 24.8 0.0 0.00067 19.3 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PFH38122.1 - 7.7e-05 22.2 0.0 8.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PFH38122.1 - 0.00043 20.2 0.1 0.0037 17.2 0.1 2.3 1 1 2 3 3 3 1 RsgA GTPase SRPRB PF09439.10 PFH38122.1 - 0.0018 17.7 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 PFH38122.1 - 0.003 18.0 0.0 0.046 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Septin PF00735.18 PFH38122.1 - 0.0046 16.3 0.1 0.0078 15.5 0.1 1.3 1 0 0 1 1 1 1 Septin ATP_bind_1 PF03029.17 PFH38122.1 - 0.0099 15.7 0.1 0.3 10.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 PFH38122.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PFH38122.1 - 0.012 15.1 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DLIC PF05783.11 PFH38122.1 - 0.019 13.8 0.0 0.073 11.9 0.0 1.7 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_24 PF13479.6 PFH38122.1 - 0.021 14.6 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 PFH38122.1 - 0.022 14.4 0.0 0.042 13.4 0.0 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 PFH38122.1 - 0.024 14.1 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 PFH38122.1 - 0.025 14.5 0.1 0.089 12.7 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 PFH38122.1 - 0.03 14.1 0.1 0.095 12.4 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 PFH38122.1 - 0.05 13.6 0.0 0.089 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 PFH38122.1 - 0.063 13.7 0.0 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase FeoB_N PF02421.18 PFH38122.1 - 0.075 12.6 0.3 0.87 9.1 0.2 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B DAP3 PF10236.9 PFH38122.1 - 0.08 12.1 0.2 0.15 11.2 0.1 1.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 PFH38122.1 - 0.09 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 PFH38122.1 - 0.093 11.9 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 PFH38122.1 - 0.11 11.6 0.7 0.39 9.8 0.1 1.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA PF00004.29 PFH38122.1 - 0.11 12.9 0.0 0.42 11.0 0.0 1.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 PFH38122.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 PFH38122.1 - 0.18 12.3 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SNARE_assoc PF09335.11 PFH38123.1 - 2.4e-19 70.0 9.1 2.4e-19 70.0 9.1 2.7 3 0 0 3 3 3 1 SNARE associated Golgi protein YdjM PF04307.14 PFH38123.1 - 0.0089 15.4 0.1 0.0089 15.4 0.1 2.0 2 1 0 2 2 2 1 LexA-binding, inner membrane-associated putative hydrolase Peptidase_M24 PF00557.24 PFH38125.1 - 4.5e-50 170.3 0.0 7.1e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 PFH38125.1 - 2.6e-17 62.8 4.5 6.2e-17 61.6 4.5 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 PFH38125.1 - 1.3e-05 25.1 4.8 4.2e-05 23.6 4.8 1.9 1 0 0 1 1 1 1 MYND finger zf-FCS PF06467.14 PFH38125.1 - 0.056 13.4 6.3 0.036 14.0 3.6 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zinc-ribbons_6 PF07191.12 PFH38125.1 - 0.69 9.9 5.5 2.2 8.3 5.5 1.9 1 1 0 1 1 1 0 zinc-ribbons MFS_1 PF07690.16 PFH38126.1 - 1.7e-20 73.2 36.4 1.7e-20 73.2 36.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily PI-PLC-X PF00388.19 PFH38127.1 - 4.3e-52 175.6 0.0 7.2e-52 174.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 PFH38127.1 - 6.5e-28 97.4 0.0 1.7e-27 96.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Mcp5_PH PF12814.7 PFH38127.1 - 1.9e-13 50.6 0.0 3.2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology C2 PF00168.30 PFH38127.1 - 6.1e-11 42.5 0.0 1.1e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain PH PF00169.29 PFH38127.1 - 8.9e-05 23.0 0.4 0.00021 21.7 0.4 1.6 1 0 0 1 1 1 1 PH domain EF-hand_8 PF13833.6 PFH38127.1 - 0.00016 21.4 0.3 0.021 14.7 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 PFH38127.1 - 0.00032 21.1 3.5 0.0095 16.4 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PFH38127.1 - 0.00069 19.3 0.4 0.5 10.4 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.6 PFH38127.1 - 0.0015 18.4 0.3 0.0032 17.3 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 PFH38127.1 - 0.013 15.0 0.0 8.7 6.2 0.0 2.8 2 0 0 2 2 2 0 EF hand PH_2 PF08458.10 PFH38127.1 - 0.13 12.7 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Bim_N PF06773.11 PFH38127.1 - 1 9.1 3.9 0.74 9.5 1.2 2.1 2 0 0 2 2 2 0 Bim protein N-terminus Ribosomal_S21 PF01165.20 PFH38131.1 - 0.12 12.1 0.3 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S21 SRR1 PF07985.12 PFH38132.1 - 5.6e-15 55.1 0.5 1.1e-14 54.2 0.5 1.5 1 0 0 1 1 1 1 SRR1 Hemolysin_N PF12563.8 PFH38133.1 - 0.046 13.3 0.4 0.11 12.1 0.4 1.5 1 0 0 1 1 1 0 Hemolytic toxin N terminal CPP1-like PF11833.8 PFH38133.1 - 3.7 7.2 5.2 5.7 6.5 2.5 2.5 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Peptidase_S8 PF00082.22 PFH38134.1 - 1.4e-44 152.6 1.1 2.2e-44 151.9 1.1 1.2 1 0 0 1 1 1 1 Subtilase family Pep1_7 PF17232.2 PFH38134.1 - 0.78 10.2 2.8 7 7.2 0.3 2.4 2 0 0 2 2 2 0 Elicitor peptide 1-7 EAGR_box PF16713.5 PFH38136.1 - 0.02 14.5 23.5 0.35 10.6 3.6 2.8 2 1 0 2 2 2 0 Enriched in aromatic and glycine Residues box SCNM1_acidic PF15805.5 PFH38136.1 - 0.15 11.8 0.1 0.15 11.8 0.1 2.8 2 1 1 3 3 3 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 Calcyon PF06387.11 PFH38137.1 - 1.1 9.2 14.9 1.9 8.4 0.2 5.1 4 2 1 5 5 5 0 D1 dopamine receptor-interacting protein (calcyon) Prok-E2_C PF14459.6 PFH38137.1 - 1.4 9.1 5.6 8.7 6.5 0.1 4.3 3 2 3 6 6 6 0 Prokaryotic E2 family C FOG_N PF15888.5 PFH38137.1 - 2.4 8.6 41.2 7.2 7.0 0.1 10.2 8 2 2 11 11 11 0 Folded gastrulation N-terminus CPW_WPC PF09717.10 PFH38137.1 - 4 8.5 32.9 14 6.7 0.4 9.3 5 3 2 7 7 7 0 Plasmodium falciparum domain of unknown function (CPW_WPC) UCH PF00443.29 PFH38139.1 - 2.3e-11 43.7 0.0 1.8e-06 27.7 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase H_PPase PF03030.16 PFH38143.1 - 1e-230 767.8 37.6 1e-230 767.8 37.6 1.3 1 1 0 1 1 1 1 Inorganic H+ pyrophosphatase COX14 PF14880.6 PFH38144.1 - 2.7e-16 59.1 1.1 3.4e-16 58.8 1.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c assembly ANAPC5 PF12862.7 PFH38144.1 - 0.081 13.0 0.1 0.14 12.3 0.1 1.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 DivIC PF04977.15 PFH38144.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Septum formation initiator RCC1 PF00415.18 PFH38145.1 - 1.1e-119 391.0 50.7 1.2e-14 54.7 1.0 16.0 16 0 0 16 16 16 14 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PFH38145.1 - 1.6e-63 209.4 75.9 1.9e-09 37.0 1.4 14.4 14 0 0 14 14 14 11 Regulator of chromosome condensation (RCC1) repeat HMGL-like PF00682.19 PFH38145.1 - 0.078 12.5 0.2 0.14 11.6 0.2 1.3 1 0 0 1 1 1 0 HMGL-like Actin PF00022.19 PFH38146.1 - 2.4e-129 431.6 0.0 1.3e-128 429.1 0.0 1.8 1 1 0 1 1 1 1 Actin MFS_1 PF07690.16 PFH38147.1 - 3.5e-08 32.8 31.0 1.4e-05 24.2 11.1 3.0 3 0 0 3 3 3 2 Major Facilitator Superfamily Aminotran_1_2 PF00155.21 PFH38148.1 - 5.6e-81 272.5 0.0 6.4e-81 272.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Consortin_C PF15281.6 PFH38148.1 - 0.012 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Consortin C-terminus HisG_C PF08029.11 PFH38148.1 - 0.16 12.1 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 HisG, C-terminal domain EF-hand_7 PF13499.6 PFH38149.1 - 0.016 15.6 0.2 0.26 11.8 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 PFH38149.1 - 0.038 13.9 0.1 0.35 10.9 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 PFH38149.1 - 0.05 13.2 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 EF hand EXS PF03124.14 PFH38151.1 - 1e-71 242.0 12.5 1.4e-71 241.6 12.5 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 PFH38151.1 - 6.4e-27 95.5 0.0 1.6e-26 94.2 0.0 1.6 1 1 0 1 1 1 1 SPX domain PI3_PI4_kinase PF00454.27 PFH38152.1 - 9.9e-43 146.7 0.0 1.8e-42 145.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 PFH38152.1 - 2.7e-08 33.5 0.2 6.3e-08 32.3 0.2 1.7 1 0 0 1 1 1 1 FATC domain VPS13 PF16908.5 PFH38154.1 - 3.6e-08 33.5 0.0 3.6e-06 27.0 0.0 3.0 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 PFH38154.1 - 7e-07 29.4 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 PFH38154.1 - 6.6e-06 26.0 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Nup54 PF13874.6 PFH38155.1 - 4.6e-19 68.9 3.4 4.6e-19 68.9 3.4 2.2 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 PFH38155.1 - 0.00029 21.6 12.3 0.00029 21.6 12.3 1.9 2 0 0 2 2 2 1 Nucleoporin FG repeat region DUF3540 PF12059.8 PFH38155.1 - 0.0096 15.8 1.5 0.018 14.9 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3540) Fez1 PF06818.15 PFH38155.1 - 3.6 8.0 10.1 18 5.7 10.1 2.0 1 1 0 1 1 1 0 Fez1 HTH_31 PF13560.6 PFH38156.1 - 0.00062 20.1 0.0 0.0015 18.8 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain S4 PF01479.25 PFH38157.1 - 4.4e-12 45.5 0.5 4.4e-12 45.5 0.5 2.0 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 PFH38157.1 - 6.9e-07 30.1 1.0 1.6e-06 28.9 0.7 1.9 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Peptidase_S8 PF00082.22 PFH38158.1 - 2.7e-29 102.4 0.3 3.8e-29 101.9 0.3 1.2 1 0 0 1 1 1 1 Subtilase family ubiquitin PF00240.23 PFH38159.1 - 3.9e-14 52.2 0.1 3.5e-06 26.7 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_4 PF18036.1 PFH38159.1 - 0.13 12.4 0.3 11 6.1 0.0 3.3 3 1 0 3 3 3 0 Ubiquitin-like domain RexB PF15968.5 PFH38160.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.0 2 0 0 2 2 2 0 Membrane-anchored ion channel, Abi component DUF4349 PF14257.6 PFH38160.1 - 0.18 11.3 0.1 0.18 11.3 0.1 2.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4349) MFS_1 PF07690.16 PFH38163.1 - 1.3e-09 37.5 42.9 5.5e-08 32.1 26.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4637 PF15470.6 PFH38163.1 - 0.26 11.0 0.0 0.26 11.0 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4637) Phage_holin_3_6 PF07332.11 PFH38163.1 - 2.2 8.4 0.0 2.2 8.4 0.0 3.4 5 0 0 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III DUF5090 PF17009.5 PFH38163.1 - 4.2 7.3 7.4 11 6.0 7.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Glyoxalase PF00903.25 PFH38164.1 - 1.9e-37 128.3 0.0 6.7e-18 65.1 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PFH38164.1 - 6.3e-11 42.5 0.0 0.00022 21.5 0.0 3.5 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PFH38164.1 - 6.7e-06 26.8 0.0 0.05 14.4 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 PFH38164.1 - 2.6e-05 24.1 0.0 0.76 9.7 0.0 4.1 4 1 1 5 5 5 2 Glyoxalase-like domain DUF3081 PF11280.8 PFH38164.1 - 0.0023 17.8 0.0 0.84 9.5 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3081) Glyoxalase_3 PF13468.6 PFH38164.1 - 0.11 12.6 0.0 3.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Glyoxalase-like domain CppA_N PF14506.6 PFH38164.1 - 0.18 11.9 0.0 21 5.2 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal Ribosomal_L26 PF16906.5 PFH38165.1 - 1.1e-39 134.7 5.1 1.6e-39 134.2 5.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 PFH38165.1 - 1.3e-07 31.3 4.6 3.1e-07 30.1 4.6 1.8 1 1 0 1 1 1 1 KOW motif Methyltrans_RNA PF04452.14 PFH38165.1 - 0.014 14.8 0.5 0.019 14.3 0.5 1.2 1 0 0 1 1 1 0 RNA methyltransferase DUF2981 PF11200.8 PFH38166.1 - 6.8e-51 174.0 15.6 1.3e-36 127.1 6.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2981) Tetraspanin PF00335.20 PFH38166.1 - 0.015 15.1 7.8 0.021 14.5 7.8 1.3 1 1 0 1 1 1 0 Tetraspanin family TarH PF02203.15 PFH38166.1 - 0.63 10.0 0.1 0.63 10.0 0.1 2.0 1 1 1 2 2 2 0 Tar ligand binding domain homologue Prefoldin_2 PF01920.20 PFH38167.1 - 6e-15 55.1 7.9 6e-15 55.1 7.9 1.4 1 1 0 1 1 1 1 Prefoldin subunit KxDL PF10241.9 PFH38167.1 - 0.0031 17.7 0.9 0.0031 17.7 0.9 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein TBCC_N PF16752.5 PFH38167.1 - 0.048 14.1 3.8 0.087 13.3 2.9 1.8 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF3128 PF11326.8 PFH38167.1 - 0.075 13.4 0.3 0.075 13.4 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) GAS PF13851.6 PFH38167.1 - 0.12 11.7 12.5 0.36 10.1 2.7 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 PFH38167.1 - 0.2 12.0 3.7 2.8 8.4 0.5 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) STAT_alpha PF01017.20 PFH38167.1 - 0.21 11.5 9.4 0.3 11.0 9.4 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF4407 PF14362.6 PFH38167.1 - 0.6 9.4 5.9 0.8 9.0 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HR1 PF02185.16 PFH38167.1 - 0.88 9.7 12.9 0.43 10.7 2.9 3.1 1 1 1 2 2 2 0 Hr1 repeat Csm1_N PF18504.1 PFH38167.1 - 1.1 9.6 14.0 0.32 11.4 2.5 2.7 2 1 1 3 3 3 0 Csm1 N-terminal domain CREPT PF16566.5 PFH38167.1 - 3.6 7.8 9.4 1.7 8.8 2.3 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Prefoldin PF02996.17 PFH38167.1 - 5 7.1 11.8 12 5.9 1.9 3.1 1 1 1 2 2 2 0 Prefoldin subunit UPF0242 PF06785.11 PFH38167.1 - 5.2 7.1 10.6 17 5.5 10.6 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4404 PF14357.6 PFH38167.1 - 7.4 7.3 9.8 0.54 10.9 1.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Ras PF00071.22 PFH38169.1 - 3e-51 173.3 0.0 3.6e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PFH38169.1 - 1.1e-32 112.8 0.1 2.3e-32 111.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PFH38169.1 - 7.3e-14 51.6 0.0 9e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PFH38169.1 - 4.6e-05 23.5 0.0 8.6e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PFH38169.1 - 0.00013 21.4 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PFH38169.1 - 0.00085 19.3 0.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase RNA_helicase PF00910.22 PFH38169.1 - 0.00085 19.7 0.3 0.0055 17.1 0.3 2.0 1 1 0 1 1 1 1 RNA helicase GTP_EFTU PF00009.27 PFH38169.1 - 0.0078 15.8 0.9 0.04 13.5 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 PFH38169.1 - 0.012 16.0 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ArgoMid PF16487.5 PFH38169.1 - 0.017 15.4 0.1 0.031 14.5 0.1 1.4 1 0 0 1 1 1 0 Mid domain of argonaute G-alpha PF00503.20 PFH38169.1 - 0.018 14.2 0.5 2.8 7.0 0.1 2.9 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 PFH38169.1 - 0.047 13.2 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 PFH38169.1 - 0.075 12.3 0.2 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 Septin FixO PF02433.15 PFH38169.1 - 0.081 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO NB-ARC PF00931.22 PFH38169.1 - 0.087 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 PFH38169.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 PFH38169.1 - 0.14 11.9 0.1 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 PFH38169.1 - 0.14 12.4 0.0 0.45 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 PFH38169.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.15 PFH38169.1 - 0.15 12.0 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 PFH38169.1 - 0.18 11.8 0.1 0.41 10.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 PFH38169.1 - 0.19 12.3 0.1 0.89 10.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Mito_carr PF00153.27 PFH38170.1 - 1.6e-52 175.4 2.8 2e-17 62.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Snf7 PF03357.21 PFH38171.1 - 1.9e-28 99.2 6.2 2.5e-28 98.8 6.2 1.1 1 0 0 1 1 1 1 Snf7 Ribosomal_L10 PF00466.20 PFH38172.1 - 9.8e-05 22.4 0.0 0.0005 20.1 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 ANAPC4_WD40 PF12894.7 PFH38173.1 - 6.3e-11 42.4 0.0 0.012 15.9 0.0 4.3 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PFH38173.1 - 0.00019 22.2 3.7 2.9 8.9 0.0 6.2 7 0 0 7 7 7 1 WD domain, G-beta repeat Hira PF07569.11 PFH38173.1 - 0.00098 18.9 0.1 0.0034 17.1 0.0 1.9 2 0 0 2 2 2 1 TUP1-like enhancer of split HIRA_B PF09453.10 PFH38173.1 - 0.13 12.1 0.2 0.32 10.9 0.2 1.7 1 0 0 1 1 1 0 HIRA B motif PAC1 PF16094.5 PFH38173.1 - 0.29 10.2 1.5 0.57 9.3 1.5 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 zf-CCCH PF00642.24 PFH38174.1 - 8.8e-09 35.1 12.4 0.00014 21.7 0.4 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PFH38174.1 - 0.00032 20.7 14.8 0.26 11.4 0.3 3.7 3 0 0 3 3 3 3 Zinc finger domain Torus PF16131.5 PFH38174.1 - 0.0081 16.8 5.0 0.043 14.5 1.3 2.8 2 0 0 2 2 2 1 Torus domain zf-CCCH_3 PF15663.5 PFH38174.1 - 0.043 14.0 2.7 0.76 10.0 0.9 2.6 2 0 0 2 2 2 0 Zinc-finger containing family PHF5 PF03660.14 PFH38176.1 - 4.5e-51 171.4 12.6 5.5e-51 171.1 12.6 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 PFH38176.1 - 0.15 9.9 7.4 0.16 9.8 7.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 LRR_4 PF12799.7 PFH38177.1 - 1.2e-12 47.8 0.9 0.00015 22.1 0.0 3.5 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PFH38177.1 - 6.7e-06 25.8 4.2 0.004 16.9 0.2 3.1 1 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 PFH38177.1 - 0.0045 16.9 3.1 3.2 8.0 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich repeat GAS PF13851.6 PFH38178.1 - 9.2e-44 149.2 26.3 9.2e-44 149.2 26.3 3.2 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding RrnaAD PF00398.20 PFH38180.1 - 1.7e-53 181.4 0.0 2.4e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 PFH38180.1 - 1.1e-07 32.5 0.0 2.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PFH38180.1 - 4.5e-06 26.5 0.0 6.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH38180.1 - 3.8e-05 24.4 0.0 0.0001 23.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PFH38180.1 - 8.2e-05 22.1 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 PFH38180.1 - 0.00012 22.6 0.0 0.00042 20.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PFH38180.1 - 0.0032 17.3 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 PFH38180.1 - 0.0056 15.8 0.0 0.0093 15.1 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 PFH38180.1 - 0.0088 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 PFH38180.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.19 PFH38180.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 PFH38180.1 - 0.028 13.8 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 PFH38180.1 - 0.091 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L7Ae PF01248.26 PFH38181.1 - 0.00011 21.9 1.0 0.00078 19.1 0.1 2.3 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MAT1 PF06391.13 PFH38182.1 - 0.89 9.3 4.8 1.1 9.1 4.8 1.0 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Pex14_N PF04695.13 PFH38183.1 - 2.7e-12 47.6 0.0 2.7e-12 47.6 0.0 8.0 8 1 2 10 10 10 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ku PF02735.16 PFH38184.1 - 3.8e-22 79.0 0.0 6.2e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 PFH38184.1 - 3.6e-09 37.2 0.0 1.7e-08 35.0 0.0 2.2 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm Ku_N PF03731.15 PFH38184.1 - 8.4e-08 32.2 0.0 6.7e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SPG48 PF14764.6 PFH38185.1 - 4.5e-26 91.6 1.1 1.1e-25 90.4 1.1 1.7 1 0 0 1 1 1 1 AP-5 complex subunit, vesicle trafficking SWIB PF02201.18 PFH38188.1 - 0.00025 20.9 0.0 0.032 14.1 0.0 2.5 2 0 0 2 2 2 2 SWIB/MDM2 domain 120_Rick_ant PF12574.8 PFH38188.1 - 0.067 12.4 0.5 0.1 11.8 0.5 1.2 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen SseC PF04888.12 PFH38188.1 - 0.16 11.6 1.5 0.37 10.4 1.5 1.5 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Maf1 PF09174.10 PFH38189.1 - 3.6e-19 69.6 0.0 2.6e-16 60.3 0.0 2.3 2 0 0 2 2 2 2 Maf1 regulator Synaptobrevin PF00957.21 PFH38190.1 - 2.4e-23 81.7 0.1 3.1e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PFH38190.1 - 7.8e-05 22.6 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_UL6 PF01763.16 PFH38190.1 - 0.027 13.0 0.1 0.036 12.6 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like COG2 PF06148.11 PFH38190.1 - 0.18 11.9 0.6 0.36 10.9 0.6 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Ost5 PF05251.12 PFH38191.1 - 1.8e-15 56.9 1.5 1.8e-15 56.9 1.5 2.3 3 0 0 3 3 3 1 Oligosaccharyltransferase subunit 5 Phage_holin_3_3 PF16083.5 PFH38191.1 - 0.03 14.4 0.7 0.066 13.3 0.2 1.9 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III PetM PF08041.11 PFH38191.1 - 0.045 13.3 1.2 0.15 11.7 1.2 2.0 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 PEP-CTERM PF07589.11 PFH38191.1 - 0.11 12.6 0.1 0.11 12.6 0.1 3.2 3 0 0 3 3 3 0 PEP-CTERM motif DUF4245 PF14030.6 PFH38191.1 - 0.12 12.3 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) DUF202 PF02656.15 PFH38191.1 - 0.24 11.9 4.2 0.46 11.0 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF1866 PF08952.11 PFH38192.1 - 0.12 12.2 0.0 0.4 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) SNARE PF05739.19 PFH38196.1 - 1.3e-15 57.1 0.7 1.3e-15 57.1 0.7 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 PFH38196.1 - 0.0014 18.4 14.1 0.013 15.2 0.5 2.7 3 0 0 3 3 3 2 Syntaxin Mitofilin PF09731.9 PFH38196.1 - 0.0033 16.3 4.0 0.0054 15.6 4.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Prominin PF05478.11 PFH38196.1 - 0.068 11.1 4.7 0.34 8.8 0.4 2.2 2 0 0 2 2 2 0 Prominin Adaptin_binding PF10199.9 PFH38196.1 - 0.078 13.6 6.7 4.7 7.8 2.6 2.5 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 RB_A PF01858.17 PFH38196.1 - 0.2 11.5 4.6 1.4 8.7 1.1 2.5 2 1 0 2 2 2 0 Retinoblastoma-associated protein A domain Synaptobrevin PF00957.21 PFH38196.1 - 0.42 10.4 6.1 0.46 10.3 1.3 2.7 2 0 0 2 2 2 0 Synaptobrevin DASH_Dam1 PF08653.10 PFH38196.1 - 1.1 9.2 3.8 39 4.1 0.3 3.3 4 0 0 4 4 4 0 DASH complex subunit Dam1 Use1 PF09753.9 PFH38196.1 - 1.9 8.2 11.1 8.9 5.9 11.1 2.1 1 1 0 1 1 1 0 Membrane fusion protein Use1 SKA1 PF07160.12 PFH38196.1 - 8 6.2 10.2 0.2 11.5 1.1 2.4 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Methyltransf_11 PF08241.12 PFH38197.1 - 1.1e-20 74.1 0.0 1.9e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH38197.1 - 4.7e-18 65.7 0.0 9.2e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PFH38197.1 - 2e-12 47.3 0.0 2.6e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PFH38197.1 - 2.4e-12 46.7 0.0 3.5e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 PFH38197.1 - 2.1e-11 44.5 0.0 3.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PFH38197.1 - 2.1e-09 37.3 0.0 2.9e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 PFH38197.1 - 3.4e-06 26.8 0.0 8.3e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 PFH38197.1 - 0.00012 22.0 0.0 0.00036 20.4 0.0 1.7 2 0 0 2 2 2 1 Hypothetical methyltransferase PCMT PF01135.19 PFH38197.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 PFH38197.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AKAP28 PF14469.6 PFH38198.1 - 1e-07 31.7 0.0 0.00012 21.8 0.0 2.3 2 0 0 2 2 2 2 28 kDa A-kinase anchor EF-hand_7 PF13499.6 PFH38198.1 - 6.5e-05 23.3 0.2 0.37 11.3 0.0 3.9 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 PFH38198.1 - 0.024 14.5 0.0 2.5 8.0 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain pair DUF2057 PF09829.9 PFH38198.1 - 0.23 11.6 1.0 0.48 10.6 1.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) VRR_NUC PF08774.11 PFH38199.1 - 4.4e-14 52.5 0.0 1.2e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Peptidase_U4 PF03419.13 PFH38200.1 - 0.016 14.5 2.9 0.022 14.1 2.9 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Imm31 PF15591.6 PFH38200.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 31 HRG PF16954.5 PFH38200.1 - 2.4 8.6 11.7 0.17 12.3 5.8 2.3 2 1 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF1361 PF07099.11 PFH38201.1 - 0.054 13.5 0.1 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1361) AMP-binding PF00501.28 PFH38202.1 - 6.8e-80 268.7 0.0 1.5e-79 267.6 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PFH38202.1 - 0.013 16.5 0.1 0.041 14.8 0.1 2.0 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain Met_10 PF02475.16 PFH38204.1 - 6.8e-05 22.7 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein tRNA_U5-meth_tr PF05958.11 PFH38204.1 - 0.00015 20.9 0.0 0.33 9.9 0.0 2.9 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 PFH38204.1 - 0.064 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TRM PF02005.16 PFH38204.1 - 0.14 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase ACDC PF14733.6 PFH38205.1 - 2.6e-20 72.5 1.8 4.1e-20 71.9 1.8 1.2 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 PFH38205.1 - 6.1e-20 71.2 6.5 6.7e-13 48.7 0.1 3.8 3 0 0 3 3 3 2 AP2 domain Pkinase PF00069.25 PFH38206.1 - 4e-26 92.0 0.0 5.4e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH38206.1 - 2.2e-13 50.1 0.0 2.9e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PFH38206.1 - 1.4e-05 24.1 0.1 1.9e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PFH38206.1 - 0.0003 20.8 0.6 0.0046 16.9 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 PFH38206.1 - 0.031 13.6 4.4 0.045 13.1 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family AP2 PF00847.20 PFH38207.1 - 5.6e-12 45.7 0.4 7.8e-09 35.6 0.1 3.6 3 0 0 3 3 3 2 AP2 domain PhoLip_ATPase_C PF16212.5 PFH38209.1 - 5.9e-70 235.9 28.4 5.9e-70 235.9 28.4 2.3 3 1 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PFH38209.1 - 2e-23 81.8 0.2 5.3e-23 80.5 0.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PFH38209.1 - 1e-09 39.0 0.2 0.0012 19.1 0.1 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PFH38209.1 - 3.2e-05 23.5 0.6 0.32 10.5 0.0 3.5 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 PFH38209.1 - 0.0004 20.4 0.0 0.0051 16.9 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PFH38209.1 - 0.0075 16.0 0.2 0.017 14.8 0.1 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YCII PF03795.14 PFH38210.1 - 0.011 16.2 0.0 1.3 9.4 0.0 2.7 2 0 0 2 2 2 0 YCII-related domain Ribul_P_3_epim PF00834.19 PFH38211.1 - 6e-64 215.1 0.0 7e-64 214.9 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family His_biosynth PF00977.21 PFH38211.1 - 0.017 14.6 0.0 0.068 12.6 0.0 1.9 1 1 0 2 2 2 0 Histidine biosynthesis protein IMPDH PF00478.25 PFH38211.1 - 0.1 11.6 0.1 1.4 7.8 0.1 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain OMPdecase PF00215.24 PFH38211.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Thioredoxin PF00085.20 PFH38212.1 - 1.8e-07 31.1 0.0 1.4e-06 28.2 0.0 2.4 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 PFH38212.1 - 0.00024 21.1 0.0 0.002 18.1 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 PFH38212.1 - 0.015 15.7 0.1 2.7 8.5 0.0 3.0 2 1 0 2 2 2 0 Thioredoxin-like domain Pex2_Pex12 PF04757.14 PFH38213.1 - 9.6e-18 64.6 0.0 4.4e-17 62.4 0.0 2.0 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 PFH38213.1 - 1.8e-05 24.5 3.9 2.8e-05 23.9 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CENP-Q PF13094.6 PFH38213.1 - 0.044 14.0 1.5 0.13 12.5 1.5 1.7 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-RING_2 PF13639.6 PFH38213.1 - 0.32 11.4 5.2 0.62 10.4 5.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 PFH38213.1 - 1.1 9.1 6.0 3.5 7.5 6.1 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PFH38213.1 - 1.4 8.8 4.5 3 7.8 4.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Sybindin PF04099.12 PFH38214.1 - 3.5e-21 75.6 0.0 5.1e-21 75.1 0.0 1.3 1 1 0 1 1 1 1 Sybindin-like family Phage_holin_3_6 PF07332.11 PFH38217.1 - 0.24 11.5 0.1 0.24 11.5 0.1 2.6 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III LSM PF01423.22 PFH38218.1 - 1.4e-22 79.1 0.1 1.7e-22 78.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain DLIC PF05783.11 PFH38219.1 - 6.5e-26 91.2 2.5 2.6e-23 82.6 0.0 2.5 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 PFH38219.1 - 0.072 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.6 PFH38219.1 - 0.093 13.3 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Methyltransf_11 PF08241.12 PFH38220.1 - 3.8e-12 46.7 0.0 8.5e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PFH38220.1 - 2.2e-07 31.5 0.0 6.6e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PFH38220.1 - 4.5e-07 29.8 0.0 9.1e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PFH38220.1 - 3.4e-06 26.9 0.0 8.3e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PFH38220.1 - 0.00017 22.2 0.0 0.00051 20.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PFH38220.1 - 0.00057 19.3 0.0 0.00096 18.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Glutaredoxin PF00462.24 PFH38221.1 - 5.1e-11 42.6 0.0 7.5e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin Tctex-1 PF03645.13 PFH38223.1 - 1.9e-25 89.1 4.1 2.1e-25 88.9 4.1 1.0 1 0 0 1 1 1 1 Tctex-1 family Cpn60_TCP1 PF00118.24 PFH38224.1 - 4.1e-93 312.6 17.5 6.3e-93 312.0 17.5 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ABC2_membrane PF01061.24 PFH38226.1 - 8.9e-38 129.8 13.8 1.4e-37 129.1 13.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PFH38226.1 - 4.3e-23 82.3 0.0 7.5e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PFH38226.1 - 1.1e-07 32.0 0.2 0.0027 17.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 PFH38226.1 - 3.9e-05 22.9 12.8 3.9e-05 22.9 12.8 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.6 PFH38226.1 - 0.0003 21.2 0.2 0.0013 19.1 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 PFH38226.1 - 0.0007 19.5 0.1 0.0014 18.6 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 PFH38226.1 - 0.0015 18.8 0.2 0.0071 16.6 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_29 PF13555.6 PFH38226.1 - 0.0015 18.2 0.1 0.0034 17.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PFH38226.1 - 0.0029 18.2 0.0 0.0063 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 PFH38226.1 - 0.005 16.3 0.0 0.037 13.5 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 PFH38226.1 - 0.0057 16.9 0.1 0.015 15.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PFH38226.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 PFH38226.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 PFH38226.1 - 0.032 14.3 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_18 PF13238.6 PFH38226.1 - 0.054 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 PFH38226.1 - 0.054 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 PFH38226.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 PFH38226.1 - 0.057 13.6 1.1 0.14 12.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PFH38226.1 - 0.059 13.8 0.1 0.22 12.0 0.1 2.1 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 PFH38226.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PFH38226.1 - 0.077 12.9 0.7 0.26 11.2 0.1 2.0 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 PFH38226.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 PFH38226.1 - 0.2 11.0 0.1 0.68 9.2 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family FBPase PF00316.20 PFH38227.1 - 1.2e-48 165.2 3.6 6.9e-29 100.7 1.3 2.2 1 1 1 2 2 2 2 Fructose-1-6-bisphosphatase, N-terminal domain Pkinase PF00069.25 PFH38228.1 - 5.2e-22 78.5 0.0 7.9e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PFH38228.1 - 4e-08 32.9 0.0 6.5e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 PFH38228.1 - 2.9e-05 23.5 0.0 4.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PFH38228.1 - 0.0043 17.0 0.2 0.012 15.5 0.2 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family ACOX PF01756.19 PFH38229.1 - 8.8e-43 146.0 0.0 1.6e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 PFH38229.1 - 3.4e-18 66.4 0.0 9.1e-18 65.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 PFH38229.1 - 2.3e-11 43.8 0.0 5.2e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain zf-RING_2 PF13639.6 PFH38230.1 - 1.2e-08 35.2 2.8 2.5e-08 34.1 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PFH38230.1 - 2.5e-08 33.8 1.9 4.9e-08 32.9 1.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PFH38230.1 - 7.3e-07 29.0 1.4 1.4e-06 28.1 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PFH38230.1 - 1.6e-06 28.3 5.5 1e-05 25.7 5.2 2.3 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PFH38230.1 - 4.4e-06 26.4 3.2 9.1e-06 25.4 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH38230.1 - 7.2e-05 22.7 2.5 0.00015 21.6 2.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 PFH38230.1 - 9.9e-05 21.9 1.2 0.0002 20.9 1.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 PFH38230.1 - 0.00031 20.5 1.0 0.0006 19.6 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PFH38230.1 - 0.00045 20.2 1.1 0.00089 19.3 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 PFH38230.1 - 0.0016 18.5 2.5 0.0035 17.5 2.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING SR-25 PF10500.9 PFH38230.1 - 0.0027 17.4 14.2 0.0027 17.4 14.2 6.5 7 1 0 7 7 4 1 Nuclear RNA-splicing-associated protein zf-RING_11 PF17123.5 PFH38230.1 - 0.0044 16.7 3.4 0.0087 15.8 3.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 PFH38230.1 - 0.0086 16.2 1.5 0.023 14.9 1.5 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 PFH38230.1 - 0.12 12.5 2.6 0.28 11.3 2.1 1.9 1 1 1 2 2 2 0 RING-variant domain Prok-RING_4 PF14447.6 PFH38230.1 - 0.2 11.5 3.6 1.6 8.6 3.0 2.7 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 DUF4718 PF15842.5 PFH38230.1 - 1.1 9.0 7.6 0.26 11.1 3.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) Nop PF01798.18 PFH38231.1 - 1e-77 260.7 0.0 1e-77 260.7 0.0 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 PFH38231.1 - 1.1e-12 48.1 0.0 1.1e-12 48.1 0.0 3.2 3 0 0 3 3 3 1 NOP5NT (NUC127) domain DUF4604 PF15377.6 PFH38231.1 - 0.15 12.4 22.2 0.031 14.7 18.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Cdh1_DBD_1 PF18196.1 PFH38231.1 - 0.77 10.1 18.7 3.3 8.1 18.7 2.1 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 RR_TM4-6 PF06459.12 PFH38231.1 - 1.1 9.1 16.6 2 8.2 16.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 PFH38231.1 - 2.2 6.5 17.4 3.4 5.8 17.4 1.3 1 0 0 1 1 1 0 CDC45-like protein PCNA_N PF00705.18 PFH38232.1 - 9.9e-46 154.6 5.0 9.9e-46 154.6 5.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 PFH38232.1 - 9.9e-31 106.6 0.0 2.6e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 PFH38232.1 - 6.1e-06 25.9 0.2 8.6e-06 25.4 0.2 1.2 1 0 0 1 1 1 1 Rad9 NaeI PF09126.10 PFH38232.1 - 0.14 11.3 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease NaeI DUF3989 PF13150.6 PFH38234.1 - 0.085 12.6 0.3 12 5.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) EMC3_TMCO1 PF01956.16 PFH38235.1 - 0.19 11.4 0.1 0.4 10.4 0.1 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2207 PF09972.9 PFH38235.1 - 1.2 7.8 2.0 17 4.1 1.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2542 PF10808.8 PFH38235.1 - 1.2 9.6 4.7 1.1 9.8 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2542) AAA PF00004.29 PFH38237.1 - 8e-30 104.0 0.0 2.4e-29 102.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PFH38237.1 - 5.3e-07 29.4 0.9 1.5e-06 27.9 0.1 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 PFH38237.1 - 6e-05 23.5 0.0 6e-05 23.5 0.0 5.2 5 0 0 5 5 5 1 AAA ATPase domain IstB_IS21 PF01695.17 PFH38237.1 - 0.027 14.2 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 PFH38237.1 - 0.071 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PFH38237.1 - 0.086 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain CDC50 PF03381.15 PFH38238.1 - 2.5e-32 112.5 0.0 4.1e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PKD_channel PF08016.12 PFH38239.1 - 5e-11 41.9 55.3 6.3e-10 38.3 15.2 5.1 4 2 0 4 4 4 3 Polycystin cation channel Ion_trans PF00520.31 PFH38239.1 - 2.7e-07 30.1 14.4 2.7e-07 30.1 14.4 3.8 4 0 0 4 4 4 3 Ion transport protein DUF1180 PF06679.12 PFH38239.1 - 5.4e-06 26.9 0.6 6e-05 23.5 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) IFT20 PF14931.6 PFH38239.1 - 1.6 8.9 8.2 4.5 7.5 8.2 1.6 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 PAP2 PF01569.21 PFH38240.1 - 4.4e-25 88.0 4.7 9.5e-25 87.0 4.7 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 PFH38240.1 - 0.0058 16.3 6.1 0.019 14.6 1.6 2.5 2 1 0 2 2 2 1 PAP2 superfamily SAND PF01342.21 PFH38240.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 SAND domain PAP2_C PF14360.6 PFH38240.1 - 4 8.0 7.8 3.7 8.2 3.1 2.9 2 1 0 2 2 2 0 PAP2 superfamily C-terminal Thioredoxin PF00085.20 PFH38241.1 - 1.2e-26 92.6 0.0 1.7e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 PFH38241.1 - 0.00049 20.1 0.2 0.00087 19.3 0.0 1.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 PFH38241.1 - 0.00057 19.9 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 PFH38241.1 - 0.00076 19.9 0.1 0.0051 17.2 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 PFH38241.1 - 0.0052 16.6 0.0 0.0081 16.0 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 PFH38241.1 - 0.0083 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 PFH38241.1 - 0.04 14.3 0.0 3.9 7.9 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like OST3_OST6 PF04756.13 PFH38241.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF3379 PF11859.8 PFH38241.1 - 0.18 11.1 0.1 0.32 10.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) DUF3789 PF12664.7 PFH38241.1 - 0.21 11.4 6.7 0.47 10.2 6.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) DUF3325 PF11804.8 PFH38241.1 - 9.2 6.5 8.4 0.35 11.1 1.4 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) Symplekin_C PF12295.8 PFH38243.1 - 4.1e-42 144.4 0.0 1e-41 143.1 0.0 1.6 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal SLBP_RNA_bind PF15247.6 PFH38244.1 - 0.012 15.7 2.5 0.012 15.7 2.5 2.1 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain CPW_WPC PF09717.10 PFH38245.1 - 2e-82 272.1 46.8 7.5e-18 65.3 2.7 5.0 5 0 0 5 5 5 5 Plasmodium falciparum domain of unknown function (CPW_WPC) MbtH PF03621.13 PFH38245.1 - 1.1 8.7 6.2 2.7 7.5 0.1 3.2 4 0 0 4 4 4 0 MbtH-like protein Arm PF00514.23 PFH38246.1 - 9 6.5 7.2 53 4.1 0.1 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Hydrolase_4 PF12146.8 PFH38247.1 - 0.093 12.0 0.0 2.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 UPF0176_N PF17773.1 PFH38248.1 - 4.8e-21 74.9 0.0 9e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 PFH38248.1 - 6.6e-13 48.8 11.9 6.6e-13 48.8 11.9 2.1 2 0 0 2 2 2 1 Rhodanase C-terminal Methyltransf_3 PF01596.17 PFH38248.1 - 5.4e-12 45.4 0.0 0.0033 16.6 0.0 4.2 4 0 0 4 4 4 3 O-methyltransferase Methyltransf_24 PF13578.6 PFH38248.1 - 0.00091 20.2 0.2 3.8 8.6 0.0 3.8 2 1 0 2 2 2 2 Methyltransferase domain Rhodanese PF00581.20 PFH38248.1 - 0.0016 18.9 0.0 0.79 10.3 0.0 2.6 2 0 0 2 2 2 2 Rhodanese-like domain CAF1C_H4-bd PF12265.8 PFH38251.1 - 3.9e-23 81.5 0.1 1.7e-22 79.4 0.0 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 PFH38251.1 - 2.6e-13 50.2 4.3 0.0088 16.9 0.4 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Peptidase_C12 PF01088.21 PFH38252.1 - 4.5e-62 209.5 0.2 1.1e-61 208.3 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 PFH38252.1 - 4.7e-14 52.0 2.5 4.7e-14 52.0 2.5 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases DUF1840 PF08895.11 PFH38252.1 - 0.019 15.3 2.8 0.032 14.6 1.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) DUF2407 PF10302.9 PFH38252.1 - 0.079 13.5 0.1 0.2 12.2 0.1 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain EF-hand_1 PF00036.32 PFH38253.1 - 4.2e-33 110.4 16.6 5.9e-09 34.8 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PFH38253.1 - 9.9e-29 99.6 10.1 5e-15 55.7 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PFH38253.1 - 4.3e-25 85.5 9.7 8.2e-09 34.7 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PFH38253.1 - 1.5e-22 79.2 13.1 1.5e-12 47.2 1.0 3.6 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 PFH38253.1 - 1.7e-13 50.7 0.3 1.1e-06 28.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PFH38253.1 - 6.7e-13 47.5 17.2 0.0003 20.2 0.1 4.6 4 1 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 PFH38253.1 - 2e-07 30.9 6.5 0.022 14.7 0.6 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand Sigma54_CBD PF04963.13 PFH38253.1 - 0.0013 18.6 0.2 0.0018 18.1 0.2 1.2 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain Dockerin_1 PF00404.18 PFH38253.1 - 0.0016 18.5 0.3 1.8 8.8 0.0 2.4 2 0 0 2 2 2 2 Dockerin type I domain SPARC_Ca_bdg PF10591.9 PFH38253.1 - 0.0033 17.7 0.1 2.8 8.3 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 PFH38253.1 - 0.0092 16.3 1.1 0.85 10.0 0.3 2.6 1 1 2 3 3 3 1 EF-hand domain SUB1_ProdP9 PF18213.1 PFH38253.1 - 0.025 14.4 1.0 0.097 12.5 0.3 2.0 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 EcoR124_C PF12008.8 PFH38253.1 - 0.031 13.9 3.8 0.033 13.8 3.0 1.3 1 1 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal SurA_N_3 PF13624.6 PFH38253.1 - 0.043 13.6 0.6 2.5 7.9 0.0 2.2 1 1 1 2 2 2 0 SurA N-terminal domain FlgD PF03963.14 PFH38253.1 - 0.079 13.3 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region SurA_N_2 PF13623.6 PFH38253.1 - 0.1 12.5 1.3 11 5.9 0.2 2.5 2 1 0 2 2 2 0 SurA N-terminal domain NUDIX PF00293.28 PFH38254.1 - 0.055 13.5 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 NUDIX domain H_lectin PF09458.10 PFH38255.1 - 3.9e-05 23.7 0.2 0.00014 22.0 0.1 2.1 2 0 0 2 2 2 1 H-type lectin domain TSP_1 PF00090.19 PFH38255.1 - 0.0048 17.1 3.9 0.0048 17.1 3.9 7.6 7 0 0 7 7 7 3 Thrombospondin type 1 domain Spc7 PF08317.11 PFH38256.1 - 0.048 12.6 28.7 0.48 9.2 10.5 2.6 2 0 0 2 2 2 0 Spc7 kinetochore protein FliD_C PF07195.12 PFH38256.1 - 0.39 10.1 4.1 2 7.8 0.5 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus CDT1_C PF16679.5 PFH38257.1 - 0.0011 19.3 1.2 0.0031 17.9 1.2 1.7 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Fib_alpha PF08702.10 PFH38258.1 - 0.0089 16.2 0.6 0.013 15.7 0.6 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Neil1-DNA_bind PF09292.10 PFH38258.1 - 0.18 11.8 0.1 0.39 10.7 0.1 1.5 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind PITH PF06201.13 PFH38259.1 - 2.6e-24 86.2 0.0 1.9e-23 83.4 0.0 1.9 1 1 0 1 1 1 1 PITH domain CDC45 PF02724.14 PFH38260.1 - 0.88 7.8 14.6 1.2 7.3 14.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Mitofilin PF09731.9 PFH38260.1 - 5.9 5.6 16.5 6.9 5.4 16.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TPR_1 PF00515.28 PFH38263.1 - 4.2e-08 32.7 2.0 0.2 11.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PFH38263.1 - 5.3e-07 29.3 2.4 0.084 13.0 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PFH38263.1 - 0.00045 19.8 0.4 0.15 11.7 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.6 PFH38263.1 - 0.055 13.5 1.1 0.82 9.8 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 PFH38263.1 - 0.21 11.9 4.7 0.75 10.1 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3597 PF12200.8 PFH38263.1 - 9.2 6.8 0.0 9.2 6.8 0.0 4.9 5 1 0 5 5 5 0 Domain of unknown function (DUF3597) DMRT-like PF15791.5 PFH38264.1 - 0.66 10.4 6.9 0.2 12.1 1.5 3.1 2 1 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 ALG11_N PF15924.5 PFH38266.1 - 3.3e-19 69.8 5.4 1.3e-06 28.6 0.1 5.2 5 0 0 5 5 5 4 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 PFH38266.1 - 7.6e-09 35.3 0.0 2.8e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PFH38266.1 - 4.9e-05 23.8 0.2 0.00096 19.6 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 DAP10 PF07213.11 PFH38266.1 - 0.24 11.4 2.0 1.1 9.3 2.0 2.1 1 0 0 1 1 1 0 DAP10 membrane protein DNA_pol_A_exo1 PF01612.20 PFH38268.1 - 2.3e-38 131.7 0.0 3.2e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 PFH38268.1 - 6.2e-08 32.5 0.1 2e-07 30.9 0.1 1.9 1 0 0 1 1 1 1 HRDC domain Lactamase_B_2 PF12706.7 PFH38269.1 - 3.8e-19 69.0 0.1 1.2e-09 38.0 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PFH38269.1 - 2.4e-06 27.7 0.0 5.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 PFH38269.1 - 0.0037 16.7 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 PFH38269.1 - 0.0068 16.3 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain LEAP-2 PF07359.11 PFH38271.1 - 0.057 13.3 0.5 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Cys_Knot_tox PF17486.2 PFH38271.1 - 0.27 11.5 2.4 0.51 10.6 2.4 1.4 1 0 0 1 1 1 0 Cystine knot toxins EF-hand_1 PF00036.32 PFH38272.1 - 6.1e-15 53.6 4.9 9.1e-07 28.0 0.9 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PFH38272.1 - 9.5e-13 47.0 3.5 2.5e-05 23.9 0.6 2.9 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PFH38272.1 - 3.1e-11 42.2 2.2 8.9e-05 21.8 0.6 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PFH38272.1 - 4.2e-11 42.5 1.9 1.6e-05 24.7 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 PFH38272.1 - 4.7e-11 43.0 2.6 3.6e-05 24.1 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 PFH38272.1 - 0.00026 20.8 0.5 0.17 11.7 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 PFH38272.1 - 0.0035 17.3 0.1 0.2 11.6 0.0 2.5 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 PFH38272.1 - 0.039 14.1 0.0 4.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Dockerin type I domain Caleosin PF05042.13 PFH38272.1 - 0.056 13.4 0.0 8.2 6.3 0.0 2.4 2 1 0 2 2 2 0 Caleosin related protein SPARC_Ca_bdg PF10591.9 PFH38272.1 - 0.074 13.4 0.0 14 6.0 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Pyr_redox_2 PF07992.14 PFH38273.1 - 3.3e-46 157.9 0.1 5.6e-46 157.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PFH38273.1 - 1.4e-30 105.8 1.1 2.9e-30 104.8 1.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PFH38273.1 - 4.7e-17 62.3 0.0 1.6e-16 60.6 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PFH38273.1 - 9.4e-10 38.2 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 PFH38273.1 - 0.0026 17.7 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-MYND PF01753.18 PFH38274.1 - 0.032 14.3 4.1 0.032 14.3 4.1 2.0 2 0 0 2 2 2 0 MYND finger Peptidase_S9 PF00326.21 PFH38275.1 - 6.4e-32 110.7 0.0 1.2e-31 109.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PFH38275.1 - 8.5e-08 31.8 0.2 3.6e-05 23.2 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PFH38275.1 - 1.3e-07 31.6 0.2 2.7e-06 27.2 0.3 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 PFH38275.1 - 0.0049 16.5 0.2 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 Putative esterase DLH PF01738.18 PFH38275.1 - 0.031 13.8 0.0 0.12 11.9 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Esterase_phd PF10503.9 PFH38275.1 - 0.12 11.9 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase Peptidase_S28 PF05577.12 PFH38275.1 - 0.26 10.0 0.0 0.42 9.3 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 PAP2_C PF14360.6 PFH38276.1 - 7.9e-07 29.5 12.7 0.00011 22.6 5.3 3.1 4 0 0 4 4 4 2 PAP2 superfamily C-terminal ACDC PF14733.6 PFH38277.1 - 1.9e-05 24.9 0.1 0.014 15.7 0.0 2.6 2 0 0 2 2 2 2 AP2-coincident C-terminal TPR_14 PF13428.6 PFH38278.1 - 2.1e-07 31.2 10.6 2 9.5 0.1 8.2 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 PFH38278.1 - 7.1e-05 23.2 1.9 0.047 14.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PFH38278.1 - 0.32 11.2 5.8 8.2 6.8 0.6 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Cytochrom_B_C PF00032.17 PFH38279.1 - 4.3e-10 39.8 0.2 5.2e-10 39.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Dynamitin PF04912.14 PFH38281.1 - 3.4e-39 135.3 18.8 8e-36 124.2 7.1 2.8 2 1 1 3 3 3 2 Dynamitin Nsp1_C PF05064.13 PFH38281.1 - 0.0048 16.7 0.2 0.0048 16.7 0.2 2.3 2 0 0 2 2 2 1 Nsp1-like C-terminal region DUF842 PF05811.13 PFH38281.1 - 0.046 13.4 5.2 0.094 12.4 0.3 2.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) CheR_N PF03705.15 PFH38281.1 - 0.18 11.6 0.4 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain CorA PF01544.18 PFH38281.1 - 0.21 10.9 2.6 11 5.2 1.1 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Tup_N PF08581.10 PFH38281.1 - 0.57 10.5 4.2 5 7.5 0.4 2.9 2 1 0 2 2 2 0 Tup N-terminal Prominin PF05478.11 PFH38281.1 - 0.67 7.8 1.3 17 3.2 0.3 2.3 2 0 0 2 2 2 0 Prominin Golgin_A5 PF09787.9 PFH38281.1 - 1.1 8.7 16.5 0.4 10.1 5.3 3.0 3 0 0 3 3 3 0 Golgin subfamily A member 5 Syntaxin-6_N PF09177.11 PFH38281.1 - 1.7 9.2 6.1 4.8 7.8 3.0 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CLZ PF16526.5 PFH38281.1 - 3.3 8.1 12.5 3.5 8.0 2.2 3.9 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TEX13 PF15186.6 PFH38281.1 - 4.7 6.9 11.8 1.4 8.6 0.0 3.3 2 1 1 3 3 3 0 Testis-expressed sequence 13 protein family PDE4_UCR PF18100.1 PFH38281.1 - 5.4 7.7 7.4 0.95 10.1 1.1 2.7 3 0 0 3 3 3 0 Phosphodiesterase 4 upstream conserved regions (UCR) Ebp2 PF05890.12 PFH38282.1 - 6.2e-30 104.7 24.9 9.6e-30 104.0 24.9 1.3 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Yip1 PF04893.17 PFH38284.1 - 0.022 14.5 6.6 0.05 13.3 6.6 1.5 1 0 0 1 1 1 0 Yip1 domain PetM PF08041.11 PFH38284.1 - 0.13 11.9 3.8 0.29 10.7 3.8 1.6 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 DuoxA PF10204.9 PFH38284.1 - 0.33 9.9 2.5 0.64 9.0 2.5 1.4 1 0 0 1 1 1 0 Dual oxidase maturation factor Ion_trans_2 PF07885.16 PFH38284.1 - 2.3 8.2 6.3 0.31 11.0 1.9 1.7 2 0 0 2 2 2 0 Ion channel Alpha-amylase PF00128.24 PFH38285.1 - 3.3e-19 69.7 0.1 1.5e-13 51.0 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 PFH38285.1 - 1.6e-07 31.7 0.0 3.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 PFH38285.1 - 0.0085 16.4 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.6 PFH38285.1 - 0.0097 15.0 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_70 PF02324.16 PFH38285.1 - 0.17 10.0 0.0 0.4 8.8 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 TFIID-31kDa PF02291.15 PFH38286.1 - 1.8e-08 34.4 0.1 3.8e-08 33.4 0.0 1.5 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit TFIID_30kDa PF03540.13 PFH38286.1 - 0.15 12.1 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit AP2 PF00847.20 PFH38287.1 - 0.0023 18.2 0.8 0.0048 17.1 0.8 1.6 1 0 0 1 1 1 1 AP2 domain MAR_sialic_bdg PF10564.9 PFH38288.1 - 0.084 12.9 0.6 0.25 11.4 0.1 2.0 2 0 0 2 2 2 0 Sialic-acid binding micronemal adhesive repeat IQ PF00612.27 PFH38288.1 - 0.47 10.4 4.5 0.43 10.5 2.5 2.0 2 0 0 2 2 2 0 IQ calmodulin-binding motif GAS PF13851.6 PFH38289.1 - 0.035 13.5 11.6 0.062 12.6 11.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 PFH38289.1 - 0.077 13.1 7.1 0.17 12.0 7.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 PFH38289.1 - 0.14 11.2 8.0 0.23 10.5 8.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin-6_N PF09177.11 PFH38289.1 - 0.14 12.7 3.3 0.3 11.7 2.7 1.9 2 0 0 2 2 1 0 Syntaxin 6, N-terminal Spc7 PF08317.11 PFH38289.1 - 0.17 10.7 12.7 0.25 10.2 12.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.6 PFH38289.1 - 0.24 11.8 11.2 1.3 9.5 2.2 2.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Phage_GP20 PF06810.11 PFH38289.1 - 0.26 11.1 10.6 0.43 10.4 5.2 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Fungal_TACC PF12709.7 PFH38289.1 - 0.3 11.6 6.4 0.3 11.5 4.7 1.8 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Csm1_N PF18504.1 PFH38289.1 - 1.2 9.5 10.1 0.6 10.5 1.7 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 PFH38289.1 - 2.6 8.1 14.1 2.9 7.9 3.5 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FapA PF03961.13 PFH38289.1 - 2.8 6.4 6.8 3.2 6.2 5.5 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A XhlA PF10779.9 PFH38289.1 - 3 8.1 5.2 0.42 10.8 0.2 2.0 2 0 0 2 2 2 0 Haemolysin XhlA DUF4407 PF14362.6 PFH38289.1 - 5.5 6.2 20.2 5.9 6.1 18.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF641 PF04859.12 PFH38289.1 - 7.4 6.9 12.6 69 3.8 11.0 2.6 2 1 0 2 2 1 0 Plant protein of unknown function (DUF641) Fez1 PF06818.15 PFH38289.1 - 7.8 6.9 17.0 13 6.1 16.0 1.8 1 1 0 1 1 1 0 Fez1 V_ATPase_I PF01496.19 PFH38289.1 - 9.1 4.1 5.0 11 3.7 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SHS2_Rpb7-N PF03876.17 PFH38290.1 - 0.14 12.6 0.0 0.35 11.3 0.0 1.7 1 1 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 G10 PF01125.17 PFH38291.1 - 9.3e-66 220.1 10.0 1e-65 220.0 10.0 1.0 1 0 0 1 1 1 1 G10 protein Synaptobrevin PF00957.21 PFH38292.1 - 2.5e-13 49.6 0.4 3.6e-13 49.1 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin BCL9 PF11502.8 PFH38293.1 - 9.2 6.2 9.3 1.2 9.0 4.6 2.0 2 0 0 2 2 2 0 B-cell lymphoma 9 protein Beta-lactamase PF00144.24 PFH38294.1 - 3.9e-33 115.1 0.0 7.9e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase ABC1 PF03109.16 PFH38294.1 - 1.8e-22 79.7 0.0 3.8e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 PFH38294.1 - 0.0034 17.0 0.0 0.013 15.1 0.0 1.8 2 0 0 2 2 2 1 RIO1 family WaaY PF06176.11 PFH38294.1 - 0.053 13.1 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Bcl-2_BAD PF10514.9 PFH38295.1 - 0.22 12.0 4.7 3.2 8.2 0.3 2.3 2 0 0 2 2 2 0 Pro-apoptotic Bcl-2 protein, BAD ERG2_Sigma1R PF04622.12 PFH38296.1 - 0.02 14.2 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 ERG2 and Sigma1 receptor like protein Afi1 PF07792.12 PFH38297.1 - 0.18 12.3 6.3 2.8 8.4 0.2 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FAM176 PF14851.6 PFH38297.1 - 1.4 8.6 11.3 2.1 8.0 2.4 2.2 2 0 0 2 2 2 0 FAM176 family Sox_N PF12444.8 PFH38297.1 - 1.7 9.8 8.2 0.46 11.6 0.6 2.3 2 0 0 2 2 2 0 Sox developmental protein N terminal MAS20 PF02064.15 PFH38297.1 - 1.7 8.7 10.9 0.19 11.8 2.3 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor V-ATPase_G PF03179.15 PFH38298.1 - 7.8e-26 90.7 8.9 9.4e-26 90.4 8.9 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 PFH38298.1 - 0.0032 17.5 7.3 0.0036 17.4 6.6 1.4 1 1 0 1 1 1 1 ATP synthase B/B' CF(0) ADPrib_exo_Tox PF03496.14 PFH38298.1 - 0.0083 15.5 0.8 0.011 15.1 0.8 1.2 1 0 0 1 1 1 1 ADP-ribosyltransferase exoenzyme DUF3552 PF12072.8 PFH38298.1 - 0.01 15.3 7.1 0.013 14.9 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) V-ATPase_G_2 PF16999.5 PFH38298.1 - 0.17 12.3 9.0 0.27 11.7 8.9 1.4 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit RSRP PF17069.5 PFH38298.1 - 0.73 9.4 2.2 0.84 9.2 2.2 1.0 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Asp PF00026.23 PFH38299.1 - 1.7e-65 221.5 0.0 2.5e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 PFH38299.1 - 3.7e-09 37.1 1.8 2.4e-06 27.9 0.0 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal AF-4 PF05110.13 PFH38299.1 - 0.13 10.3 14.1 0.18 9.9 14.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF515 PF04415.12 PFH38299.1 - 5.2 5.4 6.1 8.2 4.7 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Cytochrom_C1 PF02167.15 PFH38300.1 - 9e-89 296.9 0.0 1.6e-88 296.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 PFH38300.1 - 0.0014 18.9 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 PFH38300.1 - 0.013 16.6 0.0 0.032 15.4 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c PLDc_2 PF13091.6 PFH38301.1 - 0.00015 21.7 0.0 0.72 9.7 0.0 3.1 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 PFH38301.1 - 0.0013 18.8 3.8 0.0085 16.2 0.1 2.9 3 0 0 3 3 3 1 Phospholipase D Active site motif BSD PF03909.17 PFH38302.1 - 1.4 9.0 3.3 6.3 6.9 0.1 3.3 4 0 0 4 4 4 0 BSD domain B56 PF01603.20 PFH38303.1 - 3.8e-178 592.7 10.7 4.5e-178 592.5 10.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PRP21_like_P PF12230.8 PFH38304.1 - 1.2e-46 159.3 16.6 1.2e-46 159.3 16.6 2.5 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 PFH38304.1 - 9.1e-41 137.6 5.9 3.3e-20 71.8 1.3 2.7 2 0 0 2 2 2 2 Surp module DUF1682 PF07946.14 PFH38304.1 - 0.013 14.8 0.9 0.013 14.8 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1682) FAM220 PF15487.6 PFH38304.1 - 0.083 12.5 0.6 0.19 11.4 0.6 1.5 1 0 0 1 1 1 0 FAM220 family RMI1_N PF08585.12 PFH38304.1 - 2.2 8.0 6.8 5.8 6.6 0.0 3.2 3 0 0 3 3 3 0 RecQ mediated genome instability protein PAP2_C PF14360.6 PFH38305.1 - 5.9e-08 33.1 5.0 1.3e-06 28.8 1.5 3.7 4 0 0 4 4 4 2 PAP2 superfamily C-terminal POM121 PF15229.6 PFH38306.1 - 0.053 13.2 12.5 0.03 14.0 4.3 2.9 3 0 0 3 3 3 0 POM121 family Peptidase_M16_C PF05193.21 PFH38307.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase M16 inactive domain HTH_22 PF13309.6 PFH38307.1 - 0.14 12.3 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 HTH domain Tetraspanin PF00335.20 PFH38308.1 - 3.5 7.3 10.9 8.2 6.1 10.2 2.0 1 1 1 2 2 2 0 Tetraspanin family DnaJ-X PF14308.6 PFH38309.1 - 2.2e-55 187.4 14.6 8.8e-55 185.4 14.6 2.0 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 PFH38309.1 - 8.4e-26 89.9 3.4 2.2e-25 88.5 3.4 1.8 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.11 PFH38309.1 - 5.4e-08 33.1 2.0 1.2e-07 32.0 0.0 2.6 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain COG2 PF06148.11 PFH38309.1 - 0.049 13.7 4.5 1.9 8.6 0.2 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CRAL_TRIO PF00650.20 PFH38311.1 - 6.7e-32 110.4 0.0 1.1e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PFH38311.1 - 6.3e-07 29.6 0.0 9.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PFH38311.1 - 7.6e-06 26.0 0.1 7.6e-06 26.0 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain zf-LITAF-like PF10601.9 PFH38312.1 - 6.2e-16 58.4 9.5 1.2e-15 57.5 7.2 2.2 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain zinc_ribbon_15 PF17032.5 PFH38312.1 - 0.003 18.3 0.8 0.2 12.5 0.0 2.4 2 0 0 2 2 2 1 zinc-ribbon family Zn-ribbon_8 PF09723.10 PFH38312.1 - 0.079 13.1 2.2 0.76 10.0 0.1 2.7 3 0 0 3 3 3 0 Zinc ribbon domain FixQ PF05545.11 PFH38312.1 - 0.54 10.3 6.2 1.3 9.0 6.2 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ zinc_ribbon_4 PF13717.6 PFH38312.1 - 5.4 7.0 9.3 6.9 6.7 2.1 3.1 2 1 0 2 2 2 0 zinc-ribbon domain YABBY PF04690.13 PFH38312.1 - 8 7.0 8.1 0.25 11.9 0.6 2.1 2 0 0 2 2 2 0 YABBY protein Zn_ribbon_SprT PF17283.2 PFH38312.1 - 8.4 6.4 8.3 0.44 10.5 0.7 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 PFH38312.1 - 9.3 6.3 6.8 11 6.1 0.3 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-CCCH PF00642.24 PFH38313.1 - 1.2e-10 41.1 20.9 0.00023 21.0 2.3 3.9 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PFH38313.1 - 5.5e-08 32.6 22.5 5.6e-05 23.0 2.9 3.7 3 1 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 PFH38313.1 - 0.0002 21.1 3.4 0.0002 21.1 3.4 3.5 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 PFH38313.1 - 0.0011 19.7 11.4 0.089 13.5 3.9 2.8 1 1 2 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 PFH38313.1 - 0.034 14.3 8.0 0.34 11.1 8.0 2.1 1 1 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 PFH38313.1 - 0.11 13.1 15.3 2.9 8.5 1.1 3.9 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger DUF1796 PF08795.10 PFH38314.1 - 0.081 12.9 0.4 0.17 11.8 0.4 1.5 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) TauE PF01925.19 PFH38316.1 - 6.7e-19 68.5 27.1 4.4e-10 39.6 13.0 2.5 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE Bax1-I PF01027.20 PFH38316.1 - 1.6 8.5 20.3 0.26 11.1 4.8 2.7 2 1 1 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 ARID PF01388.21 PFH38317.1 - 3e-13 50.3 0.1 5.7e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-RING_2 PF13639.6 PFH38318.1 - 7.6e-09 35.8 5.1 7.6e-09 35.8 5.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PFH38318.1 - 4.2e-07 29.7 4.5 4.2e-07 29.7 4.5 2.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH38318.1 - 8.2e-07 28.9 1.3 1.9e-06 27.7 1.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 PFH38318.1 - 2.5e-06 27.7 3.6 2.5e-06 27.7 3.6 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PFH38318.1 - 7.3e-06 25.8 2.6 1.6e-05 24.6 2.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PFH38318.1 - 4.4e-05 23.1 1.1 9.5e-05 22.1 1.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 PFH38318.1 - 0.001 18.9 1.1 0.001 18.9 1.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PFH38318.1 - 0.0054 16.3 5.9 0.015 14.9 5.9 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 PFH38318.1 - 0.013 15.5 2.5 0.044 13.7 2.5 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 PFH38318.1 - 0.051 13.6 1.8 0.13 12.4 0.8 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger K_trans PF02705.16 PFH38318.1 - 0.096 11.2 1.1 0.14 10.6 1.1 1.1 1 0 0 1 1 1 0 K+ potassium transporter FANCL_C PF11793.8 PFH38318.1 - 0.11 12.7 4.1 0.5 10.6 4.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 PFH38318.1 - 0.11 12.4 3.7 0.14 12.1 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.7 PFH38318.1 - 2.3 8.4 5.7 5.5 7.2 5.7 1.7 1 0 0 1 1 1 0 RING-variant domain DUF3382 PF11862.8 PFH38318.1 - 3.7 7.9 6.2 0.8 10.0 0.5 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3382) 2OG-FeII_Oxy_2 PF13532.6 PFH38320.1 - 0.057 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily CedA PF10729.9 PFH38320.1 - 0.17 11.7 0.9 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Cell division activator CedA Serpin PF00079.20 PFH38321.1 - 6.2e-71 239.7 0.3 7.2e-71 239.5 0.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) RP854 PF17460.2 PFH38321.1 - 0.028 14.2 0.0 0.067 13.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein RP854 2OG-FeII_Oxy_3 PF13640.6 PFH38322.1 - 1.7e-10 41.6 0.1 4.8e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 PFH38322.1 - 2.2e-05 24.2 0.6 5.1e-05 23.1 0.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 PFH38322.1 - 5.3e-05 23.7 3.9 0.00015 22.3 3.2 2.2 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 PFH38322.1 - 0.00055 20.5 2.6 0.0013 19.3 1.7 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 PFH38322.1 - 0.0013 19.3 0.2 0.005 17.4 0.3 2.0 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_15 PF13429.6 PFH38322.1 - 0.0028 16.9 0.2 0.0051 16.1 0.2 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 PFH38322.1 - 0.0052 16.4 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.6 PFH38322.1 - 0.011 15.9 0.1 0.023 14.9 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 PFH38322.1 - 0.013 15.3 0.1 0.033 14.0 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PFH38322.1 - 0.042 14.4 1.5 0.1 13.1 1.5 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 PFH38322.1 - 0.053 14.2 6.6 0.25 12.1 6.6 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 PFH38322.1 - 0.073 13.1 0.3 0.2 11.8 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Phosducin PF02114.16 PFH38324.1 - 8.5e-10 38.0 1.3 7.2e-07 28.4 1.3 2.3 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 PFH38324.1 - 0.046 13.7 0.1 0.099 12.6 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin DUF3619 PF12279.8 PFH38324.1 - 0.12 12.7 0.2 0.19 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF4549 PF15082.6 PFH38324.1 - 0.18 11.6 2.2 0.15 11.9 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4549) Laminin_II PF06009.12 PFH38324.1 - 0.44 10.6 3.0 1 9.4 1.8 2.0 1 1 1 2 2 2 0 Laminin Domain II DUF1731 PF08338.11 PFH38326.1 - 3.5e-18 65.2 0.1 9e-18 63.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 PFH38326.1 - 0.00035 20.1 0.0 0.17 11.3 0.0 3.1 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family RNA_pol PF00940.19 PFH38327.1 - 1.1e-126 423.0 0.0 6.6e-126 420.5 0.0 2.3 2 1 0 2 2 2 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 PFH38327.1 - 3.5e-13 49.6 15.2 1.9e-08 34.1 0.0 4.9 5 1 1 6 6 6 3 DNA-directed RNA polymerase N-terminal MIF4G PF02854.19 PFH38329.1 - 3.2e-33 115.2 5.2 1.2e-16 61.0 0.3 4.5 4 0 0 4 4 4 4 MIF4G domain Upf2 PF04050.14 PFH38329.1 - 3e-15 57.1 8.2 3e-15 57.1 8.2 2.8 2 0 0 2 2 2 1 Up-frameshift suppressor 2 EspA PF03433.13 PFH38329.1 - 4.3 7.1 6.2 5.8 6.7 3.6 2.5 3 1 0 3 3 3 0 EspA-like secreted protein SprT-like PF10263.9 PFH38331.1 - 7.6e-27 93.4 0.1 1.2e-26 92.7 0.1 1.3 1 0 0 1 1 1 1 SprT-like family Img2 PF05046.14 PFH38332.1 - 2.6e-20 72.5 0.0 3.7e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ANAPC4_WD40 PF12894.7 PFH38334.1 - 0.018 15.3 0.0 0.56 10.5 0.0 3.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PFH38334.1 - 2.5 9.1 9.3 18 6.4 0.0 5.9 6 0 0 6 6 6 0 WD domain, G-beta repeat DUF99 PF01949.16 PFH38334.1 - 4.5 6.6 9.8 7.4 5.9 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function DUF99 PIP5K PF01504.18 PFH38335.1 - 7.2e-57 192.7 0.0 5.1e-33 114.5 0.0 3.1 2 1 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase SNF2_N PF00176.23 PFH38336.1 - 1.1e-34 119.7 0.1 6.9e-21 74.4 0.3 2.8 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 PFH38336.1 - 1.9e-11 44.2 0.0 4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MORN PF02493.20 PFH38337.1 - 5.1e-60 195.9 87.8 3.5e-09 36.0 1.9 11.1 11 0 0 11 11 11 9 MORN repeat Nup214_FG PF18617.1 PFH38337.1 - 1.2 9.8 7.5 9.3 6.9 0.7 3.1 3 0 0 3 3 3 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain Ribosomal_L21e PF01157.18 PFH38338.1 - 1.7e-42 143.3 3.7 2.4e-42 142.9 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e DUF1103 PF06513.11 PFH38338.1 - 0.049 13.2 1.5 0.063 12.9 1.5 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) E1_dh PF00676.20 PFH38339.1 - 1.4e-77 260.6 0.0 1.7e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 PFH38339.1 - 1.9e-09 37.5 1.5 1.2e-08 34.9 1.5 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 PFH38339.1 - 0.00072 18.8 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 PFH38339.1 - 0.0034 16.4 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain zf-CCHC_2 PF13696.6 PFH38340.1 - 4.7e-06 26.3 6.7 9.8e-06 25.3 6.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 PFH38340.1 - 0.00067 19.5 4.2 0.00067 19.5 4.2 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH38340.1 - 0.0011 19.0 2.1 0.0029 17.6 2.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PFH38340.1 - 0.0056 16.8 5.2 0.021 15.0 5.2 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 PFH38340.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn-ribbon_8 PF09723.10 PFH38340.1 - 2.1 8.6 4.4 57 3.9 0.5 3.6 3 0 0 3 3 3 0 Zinc ribbon domain zf-C3HC4 PF00097.25 PFH38340.1 - 3.8 7.4 8.5 0.061 13.2 0.6 2.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PAC4 PF16093.5 PFH38341.1 - 8.6e-12 45.1 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 ASFV_L11L PF05293.11 PFH38343.1 - 0.0073 16.6 2.7 0.0099 16.2 2.7 1.4 1 1 0 1 1 1 1 African swine fever virus (ASFV) L11L protein DUF1514 PF07438.11 PFH38343.1 - 2.9 7.8 4.4 1.3 8.9 1.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1514) Ribosomal_S27 PF01599.19 PFH38344.1 - 9.3e-27 92.9 2.8 1.5e-26 92.3 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 PFH38344.1 - 9.2e-16 57.4 0.5 1.7e-15 56.5 0.0 1.7 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 PFH38344.1 - 9.3e-09 35.0 0.3 2.2e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PFH38344.1 - 0.017 15.6 0.0 0.056 13.9 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 PFH38344.1 - 0.025 14.8 0.9 0.045 14.0 0.9 1.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain CDC45 PF02724.14 PFH38346.1 - 6.5 4.9 13.8 0.02 13.2 2.9 1.9 2 0 0 2 2 2 0 CDC45-like protein Rhomboid PF01694.22 PFH38347.1 - 4.5e-18 65.7 6.3 6.6e-18 65.2 6.3 1.3 1 0 0 1 1 1 1 Rhomboid family Pkinase PF00069.25 PFH38348.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain ORC2 PF04084.14 PFH38349.1 - 5.7e-65 219.4 0.0 8e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Alba PF01918.21 PFH38353.1 - 5.1e-05 23.0 0.0 0.0022 17.8 0.0 2.2 1 1 0 1 1 1 1 Alba Rpp20 PF12328.8 PFH38353.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P DUF374 PF04028.13 PFH38353.1 - 0.044 13.4 0.1 0.13 11.9 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF374) PhoLip_ATPase_C PF16212.5 PFH38354.1 - 2.3e-52 178.2 22.1 2.3e-52 178.2 22.1 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PFH38354.1 - 5e-18 64.6 0.5 1.3e-17 63.2 0.0 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PFH38354.1 - 6.3e-10 39.7 0.8 6.9e-05 23.2 0.1 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PFH38354.1 - 5e-08 32.9 0.1 8.6e-07 29.0 0.0 2.9 2 1 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 PFH38354.1 - 3.9e-05 23.2 1.5 0.001 18.6 0.0 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Tma16 PF11176.8 PFH38354.1 - 0.7 9.8 6.8 0.051 13.4 0.7 2.2 2 1 1 3 3 3 0 Translation machinery-associated protein 16 Peptidase_S9 PF00326.21 PFH38355.1 - 1.2e-33 116.4 0.0 1.6e-25 89.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DPPIV_N PF00930.21 PFH38355.1 - 1.8e-22 79.6 0.0 3e-12 46.0 0.0 4.2 4 0 0 4 4 4 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S15 PF02129.18 PFH38355.1 - 0.0096 15.5 2.0 0.086 12.4 0.0 3.0 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 PFH38355.1 - 0.037 13.7 0.1 0.078 12.6 0.1 1.4 1 0 0 1 1 1 0 Putative esterase PD40 PF07676.12 PFH38355.1 - 0.053 13.5 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat cEGF PF12662.7 PFH38356.1 - 5.7e-15 54.9 79.3 0.03 14.2 1.7 11.5 11 0 0 11 11 11 8 Complement Clr-like EGF-like EGF_3 PF12947.7 PFH38356.1 - 8.8e-10 38.6 106.1 5e-05 23.4 12.0 11.7 9 4 1 10 10 10 8 EGF domain hEGF PF12661.7 PFH38356.1 - 2.7e-08 34.1 104.7 0.007 17.0 0.6 12.7 13 0 0 13 13 13 9 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 PFH38356.1 - 9.4e-07 29.0 103.9 0.048 14.0 3.0 11.0 10 0 0 10 10 10 7 Pvs28 EGF domain EGF PF00008.27 PFH38356.1 - 3.2e-05 24.1 121.0 0.0099 16.2 0.8 11.9 11 0 0 11 11 11 7 EGF-like domain EGF_MSP1_1 PF12946.7 PFH38356.1 - 0.00065 19.7 93.3 0.0025 17.8 5.3 10.2 10 0 0 10 10 10 4 MSP1 EGF domain 1 EGF_CA PF07645.15 PFH38356.1 - 0.087 13.0 146.6 0.066 13.4 9.1 11.9 6 3 5 11 11 11 0 Calcium-binding EGF domain cEGF PF12662.7 PFH38357.1 - 6.1e-05 22.9 24.5 0.014 15.3 1.6 4.7 4 0 0 4 4 4 4 Complement Clr-like EGF-like EGF PF00008.27 PFH38357.1 - 0.00069 19.9 47.7 0.068 13.5 11.0 5.7 4 2 0 4 4 4 4 EGF-like domain FXa_inhibition PF14670.6 PFH38357.1 - 0.0035 17.6 51.4 0.046 14.0 7.8 4.8 4 1 0 4 4 4 3 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 PFH38357.1 - 4.1 7.7 47.2 0.24 11.6 4.9 4.6 3 1 1 4 4 4 0 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 PFH38357.1 - 5.4 7.4 41.7 0.52 10.6 3.8 4.7 4 0 0 4 4 4 0 Pvs28 EGF domain EGF_3 PF12947.7 PFH38357.1 - 7.8 6.8 45.6 1.8 8.8 6.5 4.9 3 1 1 4 4 4 0 EGF domain WD40 PF00400.32 PFH38359.1 - 3.7e-14 52.9 2.8 0.0075 17.1 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH38359.1 - 1.7e-07 31.4 0.0 1.9 8.8 0.0 5.2 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PFH38359.1 - 0.014 15.0 0.3 1.4 8.5 0.0 2.4 2 1 0 2 2 2 0 PQQ-like domain EPTP PF03736.17 PFH38359.1 - 0.09 12.8 0.0 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 EPTP domain PQQ_3 PF13570.6 PFH38359.1 - 0.4 11.2 2.6 8.4 7.0 0.1 3.9 4 1 0 4 4 4 0 PQQ-like domain Ribosomal_S8e PF01201.22 PFH38360.1 - 4.5e-54 182.3 0.1 5.5e-54 182.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e PHD PF00628.29 PFH38362.1 - 6.5e-06 25.9 3.9 6.5e-06 25.9 3.9 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 PFH38362.1 - 0.13 11.8 2.2 0.29 10.7 2.2 1.6 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 PFH38362.1 - 1 9.5 4.2 3.5 7.8 1.0 2.6 2 0 0 2 2 2 0 PHD-finger LAL_C2 PF18603.1 PFH38364.1 - 0.58 10.4 3.5 4.4 7.5 0.2 2.7 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 ASH PF15780.5 PFH38366.1 - 2e-08 34.3 0.0 1.6 9.0 0.0 5.3 4 1 0 4 4 4 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin MYCBPAP PF14646.6 PFH38366.1 - 7.6e-05 21.8 0.1 0.0037 16.3 0.0 2.8 4 0 0 4 4 4 1 MYCBP-associated protein family DUF1573 PF07610.11 PFH38366.1 - 0.012 15.6 0.0 4.4 7.4 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1573) DNA_pol_B PF00136.21 PFH38367.1 - 2.6e-107 359.4 0.0 3.5e-107 359.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_alpha_N PF12254.8 PFH38367.1 - 5.3e-14 52.1 7.1 1.4e-13 50.7 7.1 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_exo1 PF03104.19 PFH38367.1 - 7.6e-14 51.6 0.0 1.8e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 PFH38367.1 - 0.0046 16.7 2.7 0.08 12.7 0.7 2.5 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_2 PF03175.13 PFH38367.1 - 0.033 13.1 0.0 0.077 11.8 0.0 1.5 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral LIM PF00412.22 PFH38367.1 - 0.042 14.1 1.0 0.21 11.9 0.4 2.5 2 0 0 2 2 2 0 LIM domain AhpC-TSA PF00578.21 PFH38369.1 - 1.7e-35 121.6 0.0 2.1e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 PFH38369.1 - 2.9e-15 55.8 0.1 6.3e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 PFH38369.1 - 4.9e-15 55.5 0.0 6.3e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin KH_1 PF00013.29 PFH38370.1 - 1.2e-39 133.9 4.5 7.8e-15 54.5 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 PFH38370.1 - 1.5e-07 31.2 5.7 0.0027 17.5 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 PFH38370.1 - 4.7e-06 26.4 0.3 1.6 8.7 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 PFH38370.1 - 0.008 16.2 6.3 4.7 7.4 0.3 3.3 3 0 0 3 3 3 2 NusA-like KH domain DHHC PF01529.20 PFH38371.1 - 7.7e-31 107.0 12.7 7.7e-31 107.0 12.7 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4524 PF15025.6 PFH38372.1 - 0.13 12.0 0.5 0.29 10.9 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) S6PP PF05116.13 PFH38373.1 - 5.5e-34 117.8 0.0 2.7e-13 50.1 0.0 4.1 4 0 0 4 4 4 3 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 PFH38373.1 - 1.2e-12 48.2 0.0 5.5e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase ASXH PF13919.6 PFH38373.1 - 0.054 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Asx homology domain CBM53 PF16760.5 PFH38373.1 - 0.095 13.3 0.4 0.29 11.7 0.4 1.8 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Pox_F17 PF04767.12 PFH38373.1 - 0.13 12.7 2.3 0.3 11.6 2.3 1.5 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein PCI PF01399.27 PFH38375.1 - 1.7e-11 44.5 2.5 2e-11 44.3 0.1 2.4 3 0 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 PFH38375.1 - 0.00015 21.4 0.1 0.00026 20.6 0.1 1.4 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix ChuX_HutX PF06228.13 PFH38375.1 - 0.057 13.2 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX S1 PF00575.23 PFH38376.1 - 7.8e-13 48.6 0.1 4.7e-08 33.3 0.0 3.9 3 1 0 3 3 3 2 S1 RNA binding domain DUF1687 PF07955.11 PFH38376.1 - 2.6 8.6 4.9 11 6.6 4.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) Sec20 PF03908.13 PFH38377.1 - 1.5e-15 56.8 0.2 1.5e-15 56.8 0.2 2.4 3 0 0 3 3 3 1 Sec20 Vps54_N PF10475.9 PFH38377.1 - 0.045 13.0 1.8 0.083 12.2 1.8 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex TRP PF06011.12 PFH38377.1 - 0.22 10.2 0.0 0.34 9.6 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel MMR_HSR1 PF01926.23 PFH38379.1 - 6e-17 61.8 0.0 1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PFH38379.1 - 9.6e-07 28.5 0.0 0.0027 17.3 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PFH38379.1 - 7.8e-06 25.9 0.0 0.0047 16.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 PFH38379.1 - 4.9e-05 23.5 0.0 0.0028 17.7 0.0 2.2 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 PFH38379.1 - 0.00018 21.1 0.0 0.034 13.7 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_16 PF13191.6 PFH38379.1 - 0.011 16.2 1.0 0.084 13.3 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 PFH38379.1 - 0.047 13.9 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ESCRT-II PF05871.12 PFH38379.1 - 0.054 13.8 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 ESCRT-II complex subunit FtsK_SpoIIIE PF01580.18 PFH38379.1 - 0.097 12.0 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRPRB PF09439.10 PFH38379.1 - 0.22 10.9 0.0 1.2 8.6 0.0 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit adh_short_C2 PF13561.6 PFH38380.1 - 1.8e-64 217.5 2.0 2.2e-64 217.2 2.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PFH38380.1 - 9.3e-60 201.4 0.5 1.2e-59 201.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PFH38380.1 - 3.7e-22 79.1 0.4 5.9e-22 78.4 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PFH38380.1 - 8.4e-05 22.1 0.4 0.00017 21.1 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 PFH38380.1 - 0.001 19.4 0.1 0.0015 18.8 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TetR_C_25 PF17933.1 PFH38380.1 - 0.055 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF1776 PF08643.10 PFH38380.1 - 0.07 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) WD40 PF00400.32 PFH38381.1 - 0.0016 19.2 0.4 0.28 12.1 0.0 4.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Spore_III_AF PF09581.10 PFH38382.1 - 0.049 13.7 1.9 0.053 13.5 0.6 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Trypan_PARP PF05887.11 PFH38382.1 - 0.086 12.8 70.5 0.059 13.3 34.7 2.9 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) CorA PF01544.18 PFH38382.1 - 0.23 10.7 0.3 0.36 10.1 0.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CTNNBL PF08216.11 PFH38382.1 - 0.61 10.3 3.7 1.5 9.1 0.8 2.3 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear MCU PF04678.13 PFH38382.1 - 1.3 9.1 8.1 11 6.1 0.0 2.3 1 1 1 2 2 2 0 Mitochondrial calcium uniporter DnaJ PF00226.31 PFH38383.1 - 1.5e-21 76.3 0.7 4.6e-21 74.7 0.4 1.9 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 PFH38383.1 - 2.7e-13 49.8 0.0 2.9e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin DUF836 PF05768.14 PFH38383.1 - 0.11 12.9 0.9 6.4 7.3 0.1 2.4 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) AP2 PF00847.20 PFH38384.1 - 6.1e-09 36.0 1.6 1.6e-08 34.7 1.6 1.7 1 0 0 1 1 1 1 AP2 domain AAA_6 PF12774.7 PFH38385.1 - 2.2e-142 473.8 0.0 3.2e-142 473.3 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PFH38385.1 - 3.7e-109 365.5 1.8 2.8e-108 362.6 1.3 2.4 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 PFH38385.1 - 1.1e-05 25.5 0.3 0.9 9.5 0.0 4.4 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 PFH38385.1 - 0.00031 21.2 0.4 0.15 12.5 0.0 3.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF853 PF05872.12 PFH38385.1 - 0.0027 16.4 0.2 0.011 14.3 0.0 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) AAA_16 PF13191.6 PFH38385.1 - 0.013 15.9 2.5 1.5 9.1 0.0 4.0 4 0 0 4 4 4 0 AAA ATPase domain AAA_18 PF13238.6 PFH38385.1 - 0.033 14.7 0.1 0.7 10.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain TFIIF_alpha PF05793.12 PFH38385.1 - 0.22 10.1 11.2 0.39 9.2 11.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA_22 PF13401.6 PFH38385.1 - 1.7 8.9 4.1 55 4.0 0.1 3.9 3 0 0 3 3 3 0 AAA domain Dynein_C PF18199.1 PFH38386.1 - 6.1e-98 327.8 0.1 2.4e-97 325.9 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 PFH38386.1 - 3e-78 262.7 0.0 2.4e-69 233.5 0.0 3.0 3 0 0 3 3 3 2 P-loop containing dynein motor region D4 AAA_9 PF12781.7 PFH38386.1 - 1.2e-76 256.7 3.1 5.4e-73 244.8 0.0 3.5 3 1 1 4 4 4 2 ATP-binding dynein motor region AAA_lid_11 PF18198.1 PFH38386.1 - 2.8e-54 183.3 0.0 5.8e-54 182.3 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 PFH38386.1 - 7.4e-54 182.0 0.0 3e-53 180.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region MT PF12777.7 PFH38386.1 - 1.2e-49 169.2 9.1 2.1e-49 168.4 9.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PFH38386.1 - 9.4e-43 145.1 0.2 3.4e-40 136.9 0.0 3.1 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PFH38386.1 - 4.5e-15 55.9 0.1 1.5e-14 54.2 0.1 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 PFH38386.1 - 2.5e-12 46.9 0.0 5.9e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PFH38386.1 - 4.9e-05 23.3 0.0 0.017 15.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Spc7 PF08317.11 PFH38386.1 - 0.001 18.1 21.2 0.05 12.5 6.0 2.7 2 0 0 2 2 2 2 Spc7 kinetochore protein Sec8_exocyst PF04048.14 PFH38386.1 - 0.0081 16.0 3.3 0.87 9.5 0.6 2.9 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain AAA_19 PF13245.6 PFH38386.1 - 0.013 15.9 0.0 0.05 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 PFH38386.1 - 0.026 13.6 0.1 0.4 9.7 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AIP3 PF03915.13 PFH38386.1 - 0.48 9.4 8.0 0.23 10.5 1.4 2.4 2 0 0 2 2 2 0 Actin interacting protein 3 NYD-SP28_assoc PF14775.6 PFH38386.1 - 2.1 8.5 5.5 61 3.8 0.6 3.9 3 0 0 3 3 3 0 Sperm tail C-terminal domain Gln-synt_C PF00120.24 PFH38387.1 - 1.5e-122 408.9 0.0 1.8e-122 408.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 PFH38387.1 - 1e-22 79.6 0.4 1.8e-22 78.8 0.4 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain TPR_1 PF00515.28 PFH38388.1 - 8.8e-77 250.1 33.2 2.2e-10 39.9 0.0 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.6 PFH38388.1 - 1.4e-62 207.1 40.0 8.9e-07 28.5 0.1 11.4 3 2 8 11 11 11 10 TPR repeat TPR_2 PF07719.17 PFH38388.1 - 2.7e-59 192.6 29.7 1.4e-07 31.0 0.7 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_17 PF13431.6 PFH38388.1 - 2.1e-56 184.3 37.4 1.5e-06 28.1 0.0 11.6 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_8 PF13181.6 PFH38388.1 - 1.8e-50 164.9 17.4 1.4e-07 31.1 0.1 10.3 10 0 0 10 10 10 8 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 PFH38388.1 - 4.7e-48 163.8 0.0 4.8e-26 91.2 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_12 PF13424.6 PFH38388.1 - 5.6e-40 135.5 19.9 1.4e-08 34.9 0.0 8.0 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 PFH38388.1 - 1.7e-36 123.1 28.8 4.1e-05 23.3 0.2 11.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_7 PF13176.6 PFH38388.1 - 1.2e-35 118.9 11.9 6.8e-05 22.6 0.0 11.5 13 0 0 13 13 12 7 Tetratricopeptide repeat TPR_16 PF13432.6 PFH38388.1 - 7.7e-34 116.1 14.7 7.6e-07 29.7 0.1 7.9 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 PFH38388.1 - 5.6e-28 95.2 16.0 0.011 16.5 0.1 11.7 3 1 10 13 13 11 7 Tetratricopeptide repeat TPR_19 PF14559.6 PFH38388.1 - 1.1e-25 89.9 19.9 1.8e-05 25.2 0.4 7.7 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.6 PFH38388.1 - 4.4e-15 55.2 8.4 0.39 11.4 0.0 8.5 10 0 0 10 10 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 PFH38388.1 - 1.3e-14 54.0 6.5 0.014 15.5 0.0 5.7 3 1 1 5 5 5 5 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 PFH38388.1 - 1.7e-13 50.7 12.1 0.075 12.5 0.0 5.8 3 2 3 6 6 6 5 Est1 DNA/RNA binding domain Coatomer_E PF04733.14 PFH38388.1 - 2.7e-08 33.6 0.9 0.035 13.5 0.0 3.8 2 1 0 3 3 3 2 Coatomer epsilon subunit TPR_15 PF13429.6 PFH38388.1 - 3.8e-08 32.9 2.9 0.071 12.3 0.4 5.5 1 1 5 6 6 6 3 Tetratricopeptide repeat NARP1 PF12569.8 PFH38388.1 - 9.1e-07 28.2 4.6 0.19 10.6 0.3 4.1 2 2 3 5 5 5 3 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 PFH38388.1 - 1.4e-05 24.7 3.7 0.0072 15.7 1.4 3.6 3 1 1 4 4 4 2 MalT-like TPR region Wzy_C_2 PF11846.8 PFH38388.1 - 0.00029 20.8 2.9 0.25 11.2 0.0 4.0 1 1 1 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal FAT PF02259.23 PFH38388.1 - 0.00062 19.1 0.1 5.4 6.1 0.0 4.4 1 1 2 3 3 3 1 FAT domain Rapsyn_N PF10579.9 PFH38388.1 - 0.0011 19.0 0.1 0.051 13.7 0.0 3.1 3 1 1 4 4 3 1 Rapsyn N-terminal myristoylation and linker region ANAPC3 PF12895.7 PFH38388.1 - 0.031 14.5 18.4 2.3 8.5 0.1 5.1 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 PFH38388.1 - 0.36 10.5 7.0 15 5.3 0.0 4.5 3 2 2 5 5 5 0 26S proteasome subunit RPN7 DUF2225 PF09986.9 PFH38388.1 - 3.9 7.1 6.5 30 4.2 1.5 3.5 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF4198 PF10670.9 PFH38389.1 - 0.098 13.0 0.2 0.17 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) PCI PF01399.27 PFH38390.1 - 7e-12 45.8 0.1 1.6e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 PCI domain eIF3_N PF09440.10 PFH38390.1 - 0.011 16.1 0.1 0.05 14.0 0.0 2.1 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Cyt-b5 PF00173.28 PFH38391.1 - 7.4e-06 26.0 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ubiquitin PF00240.23 PFH38391.1 - 0.14 11.9 0.1 0.43 10.4 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin family PSS PF03034.15 PFH38392.1 - 1.7e-78 264.1 13.9 2.4e-78 263.7 13.9 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase VanZ PF04892.12 PFH38392.1 - 4.4 8.0 7.7 0.94 10.1 2.5 2.6 3 0 0 3 3 3 0 VanZ like family O-FucT PF10250.9 PFH38393.1 - 2.2e-12 47.4 0.0 1.4e-05 25.0 0.0 2.3 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Kinesin PF00225.23 PFH38394.1 - 2.9e-92 309.2 0.2 6e-92 308.1 0.2 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PFH38394.1 - 1.1e-18 67.6 0.1 7.7e-16 58.4 0.0 3.0 2 0 0 2 2 2 2 Microtubule binding DivIC PF04977.15 PFH38394.1 - 0.027 14.2 0.3 0.027 14.2 0.3 6.2 5 1 1 6 6 6 0 Septum formation initiator DUF1706 PF08020.11 PFH38394.1 - 0.07 13.0 3.5 7.4 6.5 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) DUF3510 PF12022.8 PFH38395.1 - 7.3e-24 84.6 0.0 3.1e-23 82.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) COG2 PF06148.11 PFH38395.1 - 8.2e-06 25.9 1.0 2e-05 24.7 0.4 2.0 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 MgtE_N PF03448.17 PFH38395.1 - 0.28 11.8 1.1 0.82 10.3 0.4 2.2 2 0 0 2 2 2 0 MgtE intracellular N domain DnaJ PF00226.31 PFH38398.1 - 2.7e-22 78.7 0.6 4.6e-22 77.9 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain SabA_adhesion PF18304.1 PFH38398.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain AP2 PF00847.20 PFH38400.1 - 2.7e-05 24.3 2.0 6.4e-05 23.1 2.0 1.7 1 0 0 1 1 1 1 AP2 domain Pkinase PF00069.25 PFH38402.1 - 4.1e-48 164.0 0.0 5.3e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH38402.1 - 5.1e-30 104.6 0.0 6.8e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PFH38402.1 - 4.4e-06 25.7 0.3 3.2e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Patatin PF01734.22 PFH38404.1 - 2.5e-07 31.1 1.9 1.6e-06 28.5 1.9 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Thiolase_N PF00108.23 PFH38405.1 - 7.9e-77 258.1 0.3 1.2e-76 257.5 0.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PFH38405.1 - 3.8e-47 159.0 0.3 3.8e-47 159.0 0.3 1.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 PFH38405.1 - 4.5e-05 23.1 0.3 0.00032 20.4 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 PFH38405.1 - 0.012 15.8 0.0 0.04 14.1 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal HSP70 PF00012.20 PFH38406.1 - 9e-266 882.8 3.9 1e-265 882.6 3.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PFH38406.1 - 8.3e-15 54.4 0.3 6.7e-13 48.2 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 PFH38406.1 - 0.00014 21.6 0.0 0.00062 19.5 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 PFH38406.1 - 0.002 17.2 0.3 0.55 9.2 0.2 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 PFH38406.1 - 0.0087 16.5 0.7 16 6.0 0.0 3.5 3 1 0 3 3 3 1 Cell division protein FtsA Hydantoinase_A PF01968.18 PFH38406.1 - 0.014 14.7 0.3 0.027 13.7 0.3 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase WYL_3 PF18488.1 PFH38407.1 - 0.11 12.9 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 WYL domain DUF3810 PF12725.7 PFH38407.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Peptidase_C48 PF02902.19 PFH38407.1 - 0.13 12.1 0.1 0.17 11.7 0.1 1.1 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain zf-CCCH_4 PF18044.1 PFH38409.1 - 4.5e-06 26.3 3.2 7.3e-06 25.7 3.2 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PFH38409.1 - 4.7e-06 26.5 5.4 9e-06 25.6 5.4 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 PFH38409.1 - 5.6e-05 23.8 0.1 0.00012 22.7 0.1 1.6 1 0 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 PFH38409.1 - 6.7e-05 22.7 3.1 0.00013 21.8 3.1 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SNF2_N PF00176.23 PFH38410.1 - 1.5e-16 60.1 0.0 2.4e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HNH PF01844.23 PFH38410.1 - 4.3e-07 30.0 0.6 9.5e-07 28.9 0.6 1.6 1 0 0 1 1 1 1 HNH endonuclease Helicase_C PF00271.31 PFH38410.1 - 1.1e-05 25.7 0.0 2.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C4_Topoisom PF01396.19 PFH38410.1 - 2e-05 24.2 1.6 4.9e-05 23.0 1.6 1.6 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger HNH_5 PF14279.6 PFH38410.1 - 0.00033 20.5 0.2 0.00073 19.4 0.2 1.5 1 0 0 1 1 1 1 HNH endonuclease ResIII PF04851.15 PFH38410.1 - 0.055 13.5 0.0 0.71 9.8 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATG101 PF07855.12 PFH38411.1 - 4.9e-08 33.1 0.0 0.00035 20.6 0.0 2.2 2 0 0 2 2 2 2 Autophagy-related protein 101 WD40 PF00400.32 PFH38412.1 - 9.6e-08 32.6 6.6 0.0028 18.5 0.2 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 PFH38412.1 - 0.04 12.6 3.2 0.048 12.3 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PFH38412.1 - 0.11 12.8 0.0 2.9 8.3 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoside_tran PF01733.18 PFH38413.1 - 6.8e-25 88.1 0.8 4.7e-24 85.3 0.8 2.0 1 1 0 1 1 1 1 Nucleoside transporter Brix PF04427.18 PFH38416.1 - 6.3e-42 143.9 0.0 1e-41 143.2 0.0 1.3 1 0 0 1 1 1 1 Brix domain Nsp1_C PF05064.13 PFH38417.1 - 2.6e-14 53.0 0.2 6e-14 51.8 0.2 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 PFH38417.1 - 2e-11 44.6 142.4 7e-06 26.8 29.0 6.5 1 1 3 5 5 5 4 Nucleoporin FG repeat region Nup54 PF13874.6 PFH38417.1 - 0.16 12.1 7.1 0.025 14.7 1.9 1.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 APP_E2 PF12925.7 PFH38417.1 - 1.5 8.5 5.9 3 7.5 5.9 1.4 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein FAM220 PF15487.6 PFH38418.1 - 4.7 6.8 8.3 7.1 6.2 8.3 1.2 1 0 0 1 1 1 0 FAM220 family Macoilin PF09726.9 PFH38418.1 - 8.8 4.8 7.4 10 4.5 7.4 1.1 1 0 0 1 1 1 0 Macoilin family BUD22 PF09073.10 PFH38418.1 - 9.4 5.5 38.0 12 5.1 38.0 1.1 1 0 0 1 1 1 0 BUD22 SNF2_N PF00176.23 PFH38419.1 - 2.3e-67 227.2 0.3 4.2e-67 226.3 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PFH38419.1 - 4.2e-21 75.4 0.0 3.7e-18 65.9 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 PFH38419.1 - 2.2e-09 37.6 0.0 9.6e-09 35.5 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PFH38419.1 - 7.8e-06 25.8 0.0 2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SLIDE PF09111.10 PFH38419.1 - 0.00014 21.9 0.1 0.001 19.1 0.0 2.7 2 1 0 2 2 2 1 SLIDE SWI2_SNF2 PF18766.1 PFH38419.1 - 0.0013 18.4 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 PFH38419.1 - 0.13 11.5 0.0 0.4 9.8 0.0 1.8 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Pheromone PF08015.11 PFH38419.1 - 2.8 9.0 4.2 3.7 8.7 0.0 3.2 2 0 0 2 2 2 0 Fungal mating-type pheromone FAM75 PF14650.6 PFH38420.1 - 10 5.6 6.6 16 4.9 6.6 1.2 1 0 0 1 1 1 0 FAM75 family FAST_1 PF06743.15 PFH38421.1 - 4.2e-05 23.4 0.4 2.1 8.3 0.1 3.7 3 0 0 3 3 3 2 FAST kinase-like protein, subdomain 1 RAP PF08373.10 PFH38421.1 - 0.0006 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 RAP domain PDZ_6 PF17820.1 PFH38421.1 - 0.081 12.8 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 PDZ domain GGDEF_2 PF17853.1 PFH38421.1 - 3.5 7.9 8.4 2.4 8.4 0.3 3.4 3 0 0 3 3 3 0 GGDEF-like domain Arm PF00514.23 PFH38422.1 - 1.4e-07 31.3 1.4 0.21 11.7 0.0 4.6 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat DUF4704 PF15787.5 PFH38422.1 - 0.0012 18.2 0.1 0.0022 17.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) Atx10homo_assoc PF09759.9 PFH38422.1 - 0.068 13.2 0.1 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 PFH38422.1 - 0.4 10.6 4.8 12 5.8 0.3 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF3361) Aldo_ket_red PF00248.21 PFH38424.1 - 2e-32 112.6 0.0 1.2e-30 106.7 0.0 2.2 1 1 0 1 1 1 1 Aldo/keto reductase family CoA_binding_2 PF13380.6 PFH38424.1 - 0.078 13.5 0.0 10 6.7 0.0 2.6 2 0 0 2 2 2 0 CoA binding domain SWIB PF02201.18 PFH38425.1 - 6e-26 90.1 0.0 8e-26 89.7 0.0 1.2 1 0 0 1 1 1 1 SWIB/MDM2 domain DLIC PF05783.11 PFH38426.1 - 2.6 6.8 2.9 4.4 6.0 2.9 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DNA_pol3_delta2 PF13177.6 PFH38427.1 - 3.8e-10 39.8 0.0 2.8e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 PFH38427.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain DUF2065 PF09838.9 PFH38427.1 - 0.019 15.0 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) AAA_16 PF13191.6 PFH38427.1 - 0.025 15.0 0.3 0.11 12.8 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain Cpn10 PF00166.21 PFH38428.1 - 1e-35 121.6 0.0 1.9e-17 63.1 0.0 2.4 3 0 0 3 3 3 2 Chaperonin 10 Kd subunit CorA PF01544.18 PFH38429.1 - 0.012 14.9 0.4 0.012 14.9 0.4 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein SOG2 PF10428.9 PFH38430.1 - 0.16 11.1 0.1 0.18 11.0 0.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein cobW PF02492.19 PFH38431.1 - 2.4e-30 105.4 0.0 2.8e-29 101.9 0.0 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 PFH38431.1 - 0.029 14.8 0.2 0.08 13.3 0.2 1.7 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 PFH38431.1 - 0.039 13.0 0.1 0.16 11.0 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein TsaE PF02367.17 PFH38431.1 - 0.054 13.5 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Kinesin PF00225.23 PFH38436.1 - 6.8e-57 192.9 0.0 4.7e-51 173.7 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 PFH38436.1 - 8.5e-13 48.5 0.0 1.6e-11 44.4 0.0 2.3 1 1 0 1 1 1 1 Microtubule binding TPR_19 PF14559.6 PFH38437.1 - 0.059 13.9 0.1 0.059 13.9 0.1 6.3 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF410 PF04190.13 PFH38437.1 - 0.15 11.9 3.2 7.8 6.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF410) LRIF1 PF15741.5 PFH38438.1 - 0.14 10.6 3.3 0.51 8.8 3.0 1.8 1 1 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 VWA PF00092.28 PFH38439.1 - 2.4e-31 109.3 0.1 3.6e-31 108.8 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.19 PFH38439.1 - 7.9e-30 102.8 70.6 3.8e-06 27.0 7.8 7.2 5 1 0 6 6 6 6 Thrombospondin type 1 domain VWA_2 PF13519.6 PFH38439.1 - 1.7e-11 44.7 0.1 2.8e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Mito_carr PF00153.27 PFH38440.1 - 1.1e-56 188.7 0.2 3.8e-18 65.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 PFH38440.1 - 0.12 12.6 0.0 5.4 7.3 0.0 2.3 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase ThiF PF00899.21 PFH38441.1 - 6.2e-20 71.6 0.0 3.5e-19 69.1 0.0 2.1 1 1 0 1 1 1 1 ThiF family PIH1 PF08190.12 PFH38442.1 - 1e-26 93.4 0.0 1.6e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 PIH1 N-terminal domain zf-Tim10_DDP PF02953.15 PFH38443.1 - 4.7e-09 35.8 0.6 5.9e-09 35.4 0.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Peptidase_M22 PF00814.25 PFH38444.1 - 7.8e-41 140.6 0.7 2.5e-20 73.3 0.3 5.5 6 0 0 6 6 6 4 Glycoprotease family RabGAP-TBC PF00566.18 PFH38446.1 - 2.8e-32 112.1 4.5 3.5e-31 108.5 0.1 2.7 3 0 0 3 3 3 2 Rab-GTPase-TBC domain RRM_1 PF00076.22 PFH38447.1 - 2.2e-09 37.0 0.0 5.3e-09 35.8 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 PFH38447.1 - 0.0038 17.0 9.2 0.006 16.4 8.0 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PFH38447.1 - 0.0077 16.4 8.8 0.0077 16.4 8.8 2.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING RL PF17797.1 PFH38447.1 - 0.013 15.4 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 RL domain zf-C3HC4 PF00097.25 PFH38447.1 - 0.034 14.0 9.1 0.072 13.0 9.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_7 PF16367.5 PFH38447.1 - 0.07 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif zf-C3HC4_2 PF13923.6 PFH38447.1 - 0.075 12.9 9.3 0.18 11.7 9.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH38447.1 - 0.077 13.0 6.9 0.2 11.7 6.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Dynactin_p62 PF05502.13 PFH38447.1 - 0.12 11.2 3.0 3.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Dynactin p62 family zf-C3HC4_3 PF13920.6 PFH38447.1 - 0.15 12.0 7.4 0.33 10.9 7.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH38447.1 - 0.3 11.1 11.2 0.77 9.8 9.7 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 PFH38447.1 - 3.1 8.2 12.2 1.7 9.1 10.0 1.8 1 1 0 1 1 1 0 Ring finger domain CS PF04969.16 PFH38448.1 - 0.083 13.9 0.0 0.27 12.3 0.0 1.8 2 0 0 2 2 2 0 CS domain ATG16 PF08614.11 PFH38449.1 - 0.00033 21.0 8.6 0.00033 21.0 8.6 2.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 PFH38449.1 - 0.00086 19.8 6.4 0.00086 19.8 6.4 2.8 3 0 0 3 3 2 1 Apg6 coiled-coil region ZapB PF06005.12 PFH38449.1 - 0.0078 16.6 5.6 0.0078 16.6 5.6 3.6 2 1 1 3 3 3 1 Cell division protein ZapB Fez1 PF06818.15 PFH38449.1 - 0.0084 16.6 8.2 0.0084 16.6 8.2 2.4 2 0 0 2 2 2 1 Fez1 AAA_13 PF13166.6 PFH38449.1 - 0.012 14.3 6.5 0.025 13.3 6.5 1.4 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 PFH38449.1 - 0.013 14.4 7.7 0.032 13.1 7.7 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 PFH38449.1 - 0.028 14.0 7.3 0.076 12.6 7.3 1.7 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF948 PF06103.11 PFH38449.1 - 0.073 13.3 0.5 0.24 11.7 0.5 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) APG17 PF04108.12 PFH38449.1 - 0.08 12.0 6.9 0.17 11.0 6.9 1.5 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF3450 PF11932.8 PFH38449.1 - 0.087 12.1 7.6 0.2 11.0 7.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 PFH38449.1 - 0.097 12.9 9.7 0.37 11.0 9.7 2.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.6 PFH38449.1 - 0.1 12.6 5.9 0.31 11.0 5.9 1.9 1 0 0 1 1 1 0 FlxA-like protein Hemagglutinin PF00509.18 PFH38449.1 - 0.1 11.0 0.2 0.18 10.2 0.2 1.3 1 0 0 1 1 1 0 Haemagglutinin V_ATPase_I PF01496.19 PFH38449.1 - 0.13 10.1 3.7 0.22 9.4 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MPS2 PF17060.5 PFH38449.1 - 0.13 11.5 6.0 0.25 10.6 6.0 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF724 PF05266.14 PFH38449.1 - 0.21 11.4 12.2 0.035 13.9 7.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Tropomyosin_1 PF12718.7 PFH38449.1 - 0.23 11.6 13.4 1.7 8.8 3.6 2.8 1 1 1 2 2 2 0 Tropomyosin like DUF641 PF04859.12 PFH38449.1 - 0.41 11.0 6.6 1.3 9.3 6.6 1.8 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF2203 PF09969.9 PFH38449.1 - 0.53 11.0 5.0 1.9 9.2 5.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Not3 PF04065.15 PFH38449.1 - 0.55 9.6 11.9 0.032 13.7 6.5 1.6 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component TMPIT PF07851.13 PFH38449.1 - 1.1 8.4 5.3 2.1 7.5 5.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein BRE1 PF08647.11 PFH38449.1 - 4 7.6 14.5 1.2 9.3 9.9 2.5 2 1 0 2 2 1 0 BRE1 E3 ubiquitin ligase Rop-like PF05082.13 PFH38449.1 - 4.7 7.1 9.2 15 5.5 0.7 4.0 4 0 0 4 4 4 0 Rop-like UPF0242 PF06785.11 PFH38449.1 - 8.5 6.4 14.7 2.4 8.2 8.8 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Chromo PF00385.24 PFH38450.1 - 1.7e-08 34.2 0.1 3.1e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain APH PF01636.23 PFH38451.1 - 0.46 10.4 0.0 0.46 10.4 0.0 3.4 4 0 0 4 4 4 0 Phosphotransferase enzyme family Hexapep PF00132.24 PFH38452.1 - 1.5e-08 34.0 8.0 0.0012 18.4 0.1 3.4 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) W2 PF02020.18 PFH38452.1 - 0.00025 21.1 0.7 0.00057 20.0 0.7 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF4954 PF16314.5 PFH38452.1 - 0.058 11.5 0.1 0.087 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 PFH38452.1 - 0.15 11.0 0.1 0.43 9.5 0.1 1.7 1 1 0 1 1 1 0 L-fucokinase DUF2284 PF10050.9 PFH38453.1 - 0.25 11.0 1.2 0.52 10.0 1.2 1.4 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) LRR_4 PF12799.7 PFH38454.1 - 6.2e-18 64.6 10.8 1.7e-07 31.4 8.4 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PFH38454.1 - 1.2e-13 50.9 12.2 1.4e-11 44.2 4.4 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 PFH38454.1 - 1.1e-11 44.3 29.8 7.7e-05 22.4 3.8 3.9 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 PFH38454.1 - 0.00022 21.0 10.9 0.31 11.2 0.0 5.5 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 PFH38454.1 - 0.00044 20.4 15.1 1.5 9.6 0.0 5.9 5 1 0 5 5 5 2 Leucine Rich Repeat CAF1 PF04857.20 PFH38455.1 - 2.8e-67 227.2 0.0 3.9e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease R3H PF01424.22 PFH38455.1 - 0.0059 16.6 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 R3H domain zf-RING_2 PF13639.6 PFH38456.1 - 9.7e-11 41.8 11.9 2.1e-10 40.8 11.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PFH38456.1 - 6.6e-08 32.2 6.5 6.6e-08 32.2 6.5 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 PFH38456.1 - 7.6e-07 29.3 9.3 7.6e-07 29.3 9.3 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PFH38456.1 - 1.5e-06 28.0 7.0 3.2e-06 26.9 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PFH38456.1 - 1.2e-05 25.0 12.8 3.3e-05 23.6 12.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PFH38456.1 - 9.8e-05 22.3 5.5 0.00028 20.9 5.5 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 PFH38456.1 - 0.00025 20.9 9.7 0.00066 19.6 9.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PFH38456.1 - 0.0054 16.7 6.9 0.014 15.5 6.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger RINGv PF12906.7 PFH38456.1 - 0.017 15.2 6.5 0.047 13.8 6.3 2.0 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 PFH38456.1 - 0.21 11.8 7.1 0.55 10.5 7.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 PFH38456.1 - 0.23 11.3 3.1 0.45 10.4 3.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 PFH38456.1 - 0.32 10.9 7.3 0.96 9.4 7.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C2H2_6 PF13912.6 PFH38456.1 - 1.6 8.9 8.3 0.62 10.1 4.9 2.2 2 1 0 2 2 2 0 C2H2-type zinc finger zf-RING-like PF08746.11 PFH38456.1 - 5.3 7.4 10.7 14 6.1 10.7 1.8 1 0 0 1 1 1 0 RING-like domain Pkinase PF00069.25 PFH38457.1 - 1.1e-77 261.0 0.0 1.5e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH38457.1 - 1.2e-40 139.4 0.0 1.7e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH38457.1 - 2.3e-07 30.4 0.0 3.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PFH38457.1 - 0.0018 17.7 0.1 0.003 16.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH38457.1 - 0.014 15.3 0.3 0.11 12.3 0.3 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 PFH38457.1 - 0.038 13.6 0.6 0.068 12.8 0.6 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 PFH38457.1 - 0.049 12.6 0.2 0.074 12.0 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain AdenylateSensor PF16579.5 PFH38457.1 - 0.11 12.9 0.1 2 8.9 0.0 2.8 2 1 1 3 3 3 0 Adenylate sensor of SNF1-like protein kinase CPSase_L_D2 PF02786.17 PFH38457.1 - 0.21 11.0 0.0 0.4 10.1 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PqqD PF05402.12 PFH38459.1 - 0.016 15.5 0.1 0.087 13.1 0.0 2.3 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Fasciclin PF02469.22 PFH38460.1 - 9.9e-14 51.7 0.0 3.9e-06 27.1 0.0 2.2 1 1 1 2 2 2 2 Fasciclin domain tRNA-synt_1d PF00750.19 PFH38461.1 - 1.5e-42 145.8 0.0 7.9e-21 74.4 0.0 4.1 4 0 0 4 4 4 4 tRNA synthetases class I (R) DALR_1 PF05746.15 PFH38461.1 - 2.4e-17 63.2 0.4 1e-16 61.2 0.4 2.2 1 1 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 PFH38461.1 - 1.9e-07 31.6 0.1 0.00021 21.8 0.0 3.9 4 0 0 4 4 4 1 Arginyl tRNA synthetase N terminal domain GatB_N PF02934.15 PFH38463.1 - 1.4e-76 257.5 0.0 7.1e-68 229.0 0.0 3.1 2 1 0 2 2 2 2 GatB/GatE catalytic domain GatB_Yqey PF02637.18 PFH38463.1 - 7.8e-14 51.8 0.0 8.9e-13 48.4 0.0 2.4 1 1 0 1 1 1 1 GatB domain Zn_Tnp_IS1595 PF12760.7 PFH38463.1 - 0.2 11.7 0.4 0.74 9.8 0.4 2.0 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DNA_pol_D_N PF18018.1 PFH38465.1 - 4.8e-34 117.3 0.0 7.3e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 PFH38465.1 - 3.2e-27 95.3 0.0 4.5e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF4006 PF13179.6 PFH38465.1 - 0.19 11.6 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Sel1 PF08238.12 PFH38466.1 - 4.2e-05 24.1 11.7 0.0041 17.8 0.4 5.8 6 0 0 6 6 6 2 Sel1 repeat Pkinase PF00069.25 PFH38467.1 - 1.2e-64 218.3 0.0 1.5e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH38467.1 - 2.1e-29 102.6 0.0 3e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PFH38467.1 - 0.027 13.8 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PFH38467.1 - 0.82 9.5 4.8 0.83 9.5 0.6 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Cation_ATPase_C PF00689.21 PFH38470.1 - 2.2e-41 141.6 3.9 3.4e-41 141.0 1.4 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PFH38470.1 - 2.6e-34 118.3 5.8 6.4e-17 61.6 0.0 3.8 4 0 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 PFH38470.1 - 1.1e-14 55.3 1.2 2.1e-05 24.9 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PFH38470.1 - 1.9e-14 53.5 0.0 9e-10 38.5 0.0 2.6 2 0 0 2 2 2 2 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PFH38470.1 - 4.2e-07 29.6 2.2 4.4e-07 29.5 0.0 2.2 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PFH38470.1 - 2e-05 24.5 1.8 0.0002 21.2 0.7 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.7 PFH38470.1 - 0.24 11.6 1.2 2.2 8.6 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) GpcrRhopsn4 PF10192.9 PFH38471.1 - 9.8e-19 67.8 4.9 1.4e-18 67.3 4.9 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 PFH38471.1 - 0.035 13.4 4.3 0.032 13.5 3.0 1.5 1 1 0 1 1 1 0 Lung seven transmembrane receptor Cytochrom_B_C PF00032.17 PFH38471.1 - 0.6 10.4 2.6 0.84 10.0 0.1 2.3 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD RNA_pol_Rpb8 PF03870.15 PFH38473.1 - 5.3e-41 140.1 0.0 5.9e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 PFH38473.1 - 2.3e-05 24.5 0.0 0.068 13.2 0.0 2.0 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G TbpB_C PF17483.2 PFH38473.1 - 0.19 12.1 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B Sulfate_transp PF00916.20 PFH38474.1 - 2.2e-29 102.4 20.2 8.2e-17 61.0 9.4 2.5 3 0 0 3 3 3 2 Sulfate permease family STAS_2 PF13466.6 PFH38474.1 - 0.097 13.0 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 STAS domain Wzy_C PF04932.15 PFH38474.1 - 0.2 11.3 0.0 0.2 11.3 0.0 3.1 3 1 0 3 3 3 0 O-Antigen ligase CS PF04969.16 PFH38477.1 - 1.2e-16 61.5 0.0 2.1e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 PFH38477.1 - 2.6e-11 43.3 0.1 5.1e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Presenilin PF01080.17 PFH38477.1 - 0.37 9.5 3.1 0.63 8.8 3.1 1.3 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 PFH38477.1 - 2.2 6.3 5.8 3.3 5.7 5.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FGF-BP1 PF06473.12 PFH38477.1 - 3.5 7.4 0.0 3.5 7.4 0.0 3.2 3 1 0 3 3 3 0 FGF binding protein 1 (FGF-BP1) Seryl_tRNA_N PF02403.22 PFH38478.1 - 2.5e-05 24.4 1.6 5e-05 23.5 1.6 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain KfrA_N PF11740.8 PFH38478.1 - 0.014 16.1 1.8 0.014 16.1 1.8 2.0 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Rrn6 PF10214.9 PFH38479.1 - 0.0048 15.5 5.5 0.0057 15.2 5.5 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DM PF00751.18 PFH38479.1 - 0.022 14.6 0.3 0.05 13.5 0.3 1.6 1 0 0 1 1 1 0 DM DNA binding domain DNA_Packaging PF11053.8 PFH38479.1 - 0.21 11.4 0.3 0.37 10.6 0.3 1.3 1 0 0 1 1 1 0 Terminase DNA packaging enzyme Polyketide_cyc PF03364.20 PFH38481.1 - 3.8e-14 53.0 0.1 7.9e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MFS_1 PF07690.16 PFH38482.1 - 1.5e-15 57.0 49.4 4.4e-10 39.0 24.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PFH38482.1 - 0.0023 16.5 2.5 0.0023 16.5 2.5 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein Peptidase_A8 PF01252.18 PFH38482.1 - 0.046 14.0 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 Signal peptidase (SPase) II PEGSRP PF07623.11 PFH38482.1 - 0.44 10.4 6.7 0.35 10.7 3.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) DUF2633 PF11119.8 PFH38483.1 - 0.19 11.7 0.0 0.48 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HA2 PF04408.23 PFH38484.1 - 2.5e-21 76.0 0.1 6e-21 74.8 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PFH38484.1 - 1.2e-20 73.6 0.0 2.4e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PFH38484.1 - 3.5e-11 43.4 0.0 7e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PFH38484.1 - 4.4e-08 33.1 0.2 1e-07 31.9 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PFH38484.1 - 1.7e-06 28.4 0.1 8e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PFH38484.1 - 6.3e-05 22.8 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PFH38484.1 - 0.00014 22.2 0.1 0.00028 21.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 PFH38484.1 - 0.00015 21.8 0.1 0.098 12.7 0.1 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 PFH38484.1 - 0.00056 19.9 0.2 0.0016 18.4 0.2 1.7 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_7 PF12775.7 PFH38484.1 - 0.0013 18.2 0.0 0.0034 16.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 PFH38484.1 - 0.002 18.5 0.1 0.0067 16.8 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 PFH38484.1 - 0.0023 17.2 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 PFH38484.1 - 0.0028 18.2 0.3 0.12 12.9 0.3 2.5 1 1 0 1 1 1 1 ABC transporter ATPase PF06745.13 PFH38484.1 - 0.016 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 PFH38484.1 - 0.016 14.2 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 PFH38484.1 - 0.03 14.0 0.2 0.074 12.7 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 PFH38484.1 - 0.061 13.0 0.1 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 PFH38484.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PFH38484.1 - 0.081 12.8 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 NACHT domain DUF932 PF06067.11 PFH38484.1 - 0.11 12.3 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF932) Herpes_ori_bp PF02399.15 PFH38484.1 - 0.17 9.9 0.1 1.4 6.8 0.1 2.1 1 1 1 2 2 2 0 Origin of replication binding protein Microtub_bd PF16796.5 PFH38484.1 - 0.17 11.8 0.1 0.5 10.3 0.1 1.7 1 0 0 1 1 1 0 Microtubule binding TrwB_AAD_bind PF10412.9 PFH38484.1 - 0.23 10.3 0.1 0.38 9.6 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TIM PF00121.18 PFH38485.1 - 3.8e-83 278.6 0.0 4.5e-83 278.4 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase SAG PF04092.13 PFH38488.1 - 1.1e-26 94.2 0.0 1.1e-14 55.3 0.0 2.1 2 0 0 2 2 2 2 SRS domain SR-25 PF10500.9 PFH38489.1 - 0.0011 18.6 12.5 0.0011 18.6 12.5 10.1 6 1 4 10 10 10 2 Nuclear RNA-splicing-associated protein Sof1 PF04158.14 PFH38490.1 - 8.6e-31 106.1 11.4 1.4e-30 105.3 11.4 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 PFH38490.1 - 2.1e-20 72.7 7.6 1.3e-07 32.2 0.1 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH38490.1 - 0.00011 22.5 0.0 2.5 8.4 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 PFH38490.1 - 0.017 15.2 0.0 14 5.7 0.0 3.5 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 PFH38490.1 - 0.027 14.3 0.0 1.1 9.2 0.0 2.5 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A AAA_18 PF13238.6 PFH38491.1 - 3.5e-30 105.2 0.1 4.4e-30 104.9 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 PFH38491.1 - 7.5e-09 36.1 0.4 6.1e-08 33.2 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PFH38491.1 - 5.5e-07 29.8 0.0 2.3e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 PFH38491.1 - 1.8e-05 25.1 0.0 3.7e-05 24.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 PFH38491.1 - 2.2e-05 24.6 0.3 0.00048 20.3 0.0 2.5 1 1 2 3 3 3 1 Adenylate kinase NTPase_1 PF03266.15 PFH38491.1 - 0.00016 21.6 0.3 0.00032 20.7 0.1 1.6 2 0 0 2 2 1 1 NTPase AAA_28 PF13521.6 PFH38491.1 - 0.00017 21.8 0.0 0.00035 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PFH38491.1 - 0.00034 20.9 0.0 0.00075 19.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 PFH38491.1 - 0.00038 20.4 1.1 0.1 12.4 0.0 2.2 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA_16 PF13191.6 PFH38491.1 - 0.00045 20.6 0.1 0.00075 19.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 PFH38491.1 - 0.00051 20.1 0.3 0.0018 18.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 PFH38491.1 - 0.0012 18.6 0.0 0.0045 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 PFH38491.1 - 0.0021 18.0 0.3 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 PFH38491.1 - 0.0022 18.4 0.0 0.0037 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 PFH38491.1 - 0.0026 17.8 0.2 0.0072 16.3 0.1 1.8 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 PFH38491.1 - 0.0038 17.3 0.0 0.012 15.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase KTI12 PF08433.10 PFH38491.1 - 0.0038 16.7 0.0 0.0067 15.9 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Viral_helicase1 PF01443.18 PFH38491.1 - 0.0054 16.5 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase SKI PF01202.22 PFH38491.1 - 0.0058 16.8 0.2 0.032 14.4 0.0 2.1 2 1 0 2 2 2 1 Shikimate kinase ATP_bind_1 PF03029.17 PFH38491.1 - 0.0066 16.3 0.5 0.013 15.3 0.2 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ATPase PF06745.13 PFH38491.1 - 0.0079 15.6 0.1 0.017 14.5 0.0 1.6 2 0 0 2 2 2 1 KaiC Cytidylate_kin PF02224.18 PFH38491.1 - 0.0079 15.9 0.0 0.015 15.0 0.0 1.5 2 0 0 2 2 2 1 Cytidylate kinase IstB_IS21 PF01695.17 PFH38491.1 - 0.013 15.3 0.0 0.044 13.5 0.0 1.9 2 1 0 2 2 2 0 IstB-like ATP binding protein RuvB_N PF05496.12 PFH38491.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 PFH38491.1 - 0.019 14.8 0.0 0.054 13.3 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 PFH38491.1 - 0.029 13.4 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 PFH38491.1 - 0.029 14.4 0.0 0.057 13.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 PFH38491.1 - 0.042 13.2 0.0 0.092 12.1 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.6 PFH38491.1 - 0.044 14.1 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 PFH38491.1 - 0.055 13.1 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 PFH38491.1 - 0.056 12.9 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_2 PF07724.14 PFH38491.1 - 0.062 13.4 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 PFH38491.1 - 0.081 13.4 0.0 0.12 12.9 0.0 1.3 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 PFH38491.1 - 0.13 12.0 0.0 0.62 9.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 PFH38491.1 - 0.15 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 PFH38491.1 - 0.15 11.3 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MeaB PF03308.16 PFH38491.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 PFH38491.1 - 0.2 11.4 0.0 0.46 10.2 0.0 1.6 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Hydin_ADK PF17213.3 PFH38491.1 - 0.21 11.8 0.0 0.36 11.1 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Epiglycanin_C PF14654.6 PFH38494.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region NTF2 PF02136.20 PFH38496.1 - 1.4e-31 109.6 0.0 1.5e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 PFH38496.1 - 0.029 14.3 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 PP_kinase_C_1 PF17941.1 PFH38496.1 - 0.06 12.9 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 1 MCM_bind PF09739.9 PFH38497.1 - 7.8e-37 127.0 4.4 1.4e-09 37.0 0.0 7.1 4 2 3 7 7 7 6 Mini-chromosome maintenance replisome factor DUF2857 PF11198.8 PFH38497.1 - 0.00029 20.7 0.1 0.00064 19.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2857) THOC2_N PF16134.5 PFH38497.1 - 0.02 13.5 0.6 0.028 13.0 0.6 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DDE_5 PF13546.6 PFH38497.1 - 0.025 13.9 0.1 0.054 12.8 0.1 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease Peptidase_S64 PF08192.11 PFH38497.1 - 0.1 11.0 3.7 0.15 10.5 3.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Radial_spoke PF04712.12 PFH38498.1 - 1.6e-89 301.1 0.4 6.5e-57 193.6 0.1 2.3 1 1 2 3 3 3 2 Radial spokehead-like protein Inositol_P PF00459.25 PFH38499.1 - 2.1e-09 37.3 0.0 0.00095 18.8 0.1 2.6 2 0 0 2 2 2 2 Inositol monophosphatase family Peptidase_M24 PF00557.24 PFH38500.1 - 3.1e-54 183.8 0.3 3.5e-52 177.2 0.1 2.1 2 0 0 2 2 2 2 Metallopeptidase family M24 AMP_N PF05195.16 PFH38500.1 - 6.8e-16 58.1 0.0 1.4e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain CRAL_TRIO_2 PF13716.6 PFH38501.1 - 2.6e-26 92.4 1.2 4.4e-26 91.7 1.2 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 PFH38501.1 - 5.2e-12 45.8 0.0 9.3e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CDC27 PF09507.10 PFH38501.1 - 0.48 9.8 15.1 0.64 9.4 15.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 PFH38501.1 - 2.7 7.5 8.6 4.7 6.7 8.6 1.4 1 0 0 1 1 1 0 PPP4R2 PBP1_TM PF14812.6 PFH38501.1 - 4.2 7.8 10.3 69 3.9 8.9 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MORN PF02493.20 PFH38503.1 - 7.7e-05 22.4 25.4 0.002 17.9 3.2 5.0 5 0 0 5 5 5 3 MORN repeat WcbI PF18588.1 PFH38503.1 - 0.2 11.3 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI MMR_HSR1_Xtn PF16897.5 PFH38504.1 - 3.6e-38 129.8 0.0 6.2e-38 129.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 PFH38504.1 - 1.1e-18 67.3 0.0 2e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 PFH38504.1 - 4e-15 55.6 0.0 6.8e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 PFH38504.1 - 1.1e-09 38.0 0.0 1.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PFH38504.1 - 5.6e-07 29.8 0.1 0.01 15.9 0.0 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 PFH38504.1 - 0.0036 16.9 0.1 18 4.8 0.0 3.4 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain AIG1 PF04548.16 PFH38504.1 - 0.0086 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family AAA_28 PF13521.6 PFH38504.1 - 0.027 14.7 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PFH38504.1 - 0.029 14.3 0.1 0.48 10.3 0.0 2.7 3 1 0 3 3 3 0 RsgA GTPase MCM PF00493.23 PFH38504.1 - 0.031 13.4 0.1 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain SRPRB PF09439.10 PFH38504.1 - 0.038 13.4 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 PFH38504.1 - 0.041 14.1 0.0 0.66 10.2 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 PFH38504.1 - 0.077 12.0 0.1 0.36 9.8 0.0 2.0 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 PFH38504.1 - 0.12 11.9 0.0 0.46 9.9 0.0 2.0 2 1 0 2 2 2 0 ADP-ribosylation factor family DUF792 PF05632.11 PFH38504.1 - 0.16 11.8 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF792) Tyr_Deacylase PF02580.16 PFH38505.1 - 1.1e-24 87.6 0.0 1.4e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase RRM_1 PF00076.22 PFH38507.1 - 8.9e-19 67.1 0.1 1.4e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_11_kDa PF06143.11 PFH38509.1 - 0.13 11.9 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Urm1 PF09138.11 PFH38510.1 - 6.9e-15 55.2 0.0 1.4e-13 50.9 0.0 2.5 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) SKIP_SNW PF02731.15 PFH38511.1 - 3.5e-70 234.8 4.6 3.5e-70 234.8 4.6 2.4 3 0 0 3 3 3 1 SKIP/SNW domain DUF2756 PF10956.8 PFH38511.1 - 0.58 10.7 6.5 2.4 8.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) DA1-like PF12315.8 PFH38512.1 - 9.7e-11 41.4 0.0 1.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Protein DA1 LRR_4 PF12799.7 PFH38513.1 - 0.028 14.9 0.3 0.068 13.6 0.3 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) HTH_23 PF13384.6 PFH38514.1 - 0.0001 22.0 0.3 0.00039 20.1 0.3 2.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_4 PF13613.6 PFH38514.1 - 0.011 15.5 0.2 0.019 14.7 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_29 PF13551.6 PFH38514.1 - 0.058 13.4 0.2 0.058 13.4 0.2 3.8 3 0 0 3 3 3 0 Winged helix-turn helix HTH_28 PF13518.6 PFH38514.1 - 0.14 12.3 3.1 0.18 12.0 0.3 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Myc_target_1 PF15179.6 PFH38515.1 - 0.3 11.0 2.9 1 9.3 1.0 2.4 2 0 0 2 2 2 0 Myc target protein 1 dUTPase PF00692.19 PFH38516.1 - 4e-16 58.9 0.0 8.7e-16 57.8 0.0 1.5 1 1 0 1 1 1 1 dUTPase Nucleoside_tran PF01733.18 PFH38517.1 - 2.7e-22 79.6 1.2 1.2e-21 77.5 1.2 1.9 1 1 0 1 1 1 1 Nucleoside transporter AP2 PF00847.20 PFH38518.1 - 1.2e-40 137.5 49.6 7.7e-09 35.7 1.0 7.9 7 0 0 7 7 7 6 AP2 domain SR-25 PF10500.9 PFH38518.1 - 3.3 7.2 15.3 5.8 6.5 12.8 2.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein IMPDH PF00478.25 PFH38519.1 - 3.4e-130 434.1 5.1 4.3e-130 433.7 5.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 PFH38519.1 - 6.7e-12 45.7 0.5 2.7e-05 24.5 0.1 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 PFH38519.1 - 1.1e-10 41.1 0.6 2.3e-10 40.1 0.6 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 PFH38519.1 - 1.2e-10 41.3 5.2 5.7e-07 29.2 3.8 2.8 2 1 0 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 PFH38519.1 - 4.3e-05 23.1 1.8 0.0085 15.6 0.1 2.6 2 1 1 3 3 3 2 Histidine biosynthesis protein ThiG PF05690.14 PFH38519.1 - 0.00013 21.3 2.7 0.00022 20.6 1.3 1.9 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 PFH38519.1 - 0.0094 15.1 0.5 2.7 7.0 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 PFH38519.1 - 0.018 14.2 0.7 0.69 9.1 0.6 2.5 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 PFH38519.1 - 0.022 13.9 1.2 0.05 12.7 1.2 1.6 1 0 0 1 1 1 0 Conserved region in glutamate synthase G3P_antiterm PF04309.12 PFH38519.1 - 0.023 14.1 0.4 0.18 11.2 0.1 2.4 2 1 1 3 3 3 0 Glycerol-3-phosphate responsive antiterminator Band_7 PF01145.25 PFH38520.1 - 2.7e-22 79.7 0.2 4.5e-22 78.9 0.2 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 PFH38520.1 - 0.0067 15.5 0.5 0.009 15.1 0.5 1.3 1 0 0 1 1 1 1 SigmaW regulon antibacterial Antigen_C PF16364.5 PFH38520.1 - 0.053 13.9 0.3 0.089 13.2 0.3 1.3 1 0 0 1 1 1 0 Cell surface antigen C-terminus XPG_N PF00752.17 PFH38522.1 - 2.2e-20 73.0 0.0 3.8e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 PFH38522.1 - 2.6e-16 59.7 0.0 7.8e-16 58.2 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 PFH38522.1 - 0.00011 21.8 0.1 0.00027 20.5 0.1 1.6 1 0 0 1 1 1 1 XPG domain containing GCFC PF07842.12 PFH38523.1 - 1.7e-38 132.9 11.6 6.9e-36 124.3 7.1 3.0 4 0 0 4 4 4 2 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 PFH38523.1 - 4.6e-11 42.4 1.7 1.5e-10 40.8 1.7 1.9 1 0 0 1 1 1 1 G-patch domain PDEase_I PF00233.19 PFH38524.1 - 8e-65 218.9 0.5 1.8e-64 217.8 0.0 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HATPase_c PF02518.26 PFH38524.1 - 4e-06 27.3 0.0 7.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PMEI PF04043.15 PFH38524.1 - 0.062 13.6 0.5 0.32 11.3 0.4 2.4 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor PDEase_I PF00233.19 PFH38525.1 - 1e-44 153.1 1.7 2.5e-44 151.8 0.2 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 PFH38525.1 - 0.0022 18.2 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 HD domain DUF2859 PF11072.8 PFH38525.1 - 0.048 13.4 1.7 2.7 7.7 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) Not3 PF04065.15 PFH38527.1 - 2.5e-79 266.0 22.3 3.3e-79 265.6 22.3 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 PFH38527.1 - 5e-37 126.9 6.1 5e-37 126.9 6.1 1.9 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 PFH38527.1 - 1.3 9.4 9.9 0.1 13.0 2.8 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Pkinase PF00069.25 PFH38528.1 - 6.1e-69 232.3 0.0 8.6e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH38528.1 - 4.1e-33 114.7 0.0 7.3e-33 113.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH38528.1 - 6.3e-05 22.4 0.1 0.0008 18.8 0.0 2.3 2 1 1 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 PFH38528.1 - 0.00044 19.3 0.7 0.00044 19.3 0.7 2.5 2 1 0 2 2 1 1 Haspin like kinase domain Kdo PF06293.14 PFH38528.1 - 0.0079 15.6 0.8 0.014 14.8 0.8 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4391 PF14335.6 PFH38528.1 - 0.051 13.3 0.0 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) APH PF01636.23 PFH38528.1 - 0.1 12.5 0.1 2.5 8.0 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family EF-G-binding_N PF07299.11 PFH38528.1 - 0.11 13.0 0.1 14 6.3 0.0 2.5 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Apt1 PF10351.9 PFH38528.1 - 0.74 8.6 12.9 1.2 8.0 12.9 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 PFH38528.1 - 1.3 8.2 15.3 2 7.5 15.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Sec3_C PF09763.9 PFH38528.1 - 3.9 5.7 9.2 5.9 5.1 9.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF4615 PF15393.6 PFH38528.1 - 6.3 7.4 6.0 14 6.3 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) FAM76 PF16046.5 PFH38528.1 - 8.1 5.7 14.1 12 5.1 14.1 1.2 1 0 0 1 1 1 0 FAM76 protein Spt5-NGN PF03439.13 PFH38529.1 - 1.1e-20 73.3 0.1 2e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 PFH38529.1 - 7.2e-08 32.1 9.1 0.1 12.6 0.0 5.9 5 0 0 5 5 5 4 KOW motif Spt5_N PF11942.8 PFH38529.1 - 0.0016 19.4 11.2 0.0016 19.4 11.2 3.5 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 PFH38529.1 - 0.0064 16.7 0.4 11 6.4 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3912) Cpn10 PF00166.21 PFH38529.1 - 0.14 12.2 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit FAST_1 PF06743.15 PFH38530.1 - 5.6e-06 26.2 0.2 0.00042 20.2 0.0 3.3 2 1 1 3 3 3 1 FAST kinase-like protein, subdomain 1 EspB_PE PF18625.1 PFH38530.1 - 6 7.4 10.8 2.1 8.8 2.1 3.4 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain ORC5_C PF14630.6 PFH38531.1 - 7e-17 61.9 0.0 2.2e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_22 PF13401.6 PFH38531.1 - 0.048 13.9 0.2 3.9 7.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PFH38531.1 - 0.45 10.9 13.4 0.057 13.8 0.4 4.2 4 0 0 4 4 4 0 AAA ATPase domain HSP20 PF00011.21 PFH38533.1 - 9.9e-13 48.1 0.0 1.5e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PFH38533.1 - 0.0021 17.6 0.0 0.016 14.7 0.0 2.4 2 1 0 2 2 2 1 HSP20-like domain found in ArsA V_ATPase_I PF01496.19 PFH38534.1 - 1.8e-259 863.1 0.0 2e-259 862.9 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family zf-Tim10_DDP PF02953.15 PFH38535.1 - 6.1e-18 64.2 2.3 8.1e-18 63.8 2.3 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Evr1_Alr PF04777.13 PFH38536.1 - 3.6e-11 43.4 0.1 7.7e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 Erv1 / Alr family Pol_alpha_B_N PF08418.10 PFH38536.1 - 0.38 10.7 2.7 0.51 10.3 2.7 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Leu_zip PF15294.6 PFH38538.1 - 0.017 14.7 0.5 0.03 13.8 0.5 1.3 1 0 0 1 1 1 0 Leucine zipper DUF4795 PF16043.5 PFH38538.1 - 0.063 12.9 0.4 0.099 12.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Cnn_1N PF07989.11 PFH38538.1 - 0.67 10.1 2.7 11 6.3 0.1 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 ADIP PF11559.8 PFH38538.1 - 0.78 9.8 5.2 2.2 8.3 5.2 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PRKG1_interact PF15898.5 PFH38538.1 - 1.9 9.5 8.0 0.2 12.6 2.6 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain IPP-2 PF04979.14 PFH38539.1 - 2.7e-20 73.4 8.7 5.9e-20 72.3 8.7 1.6 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Methyltransf_10 PF05971.12 PFH38540.1 - 1.2e-68 231.7 1.6 4.6e-44 151.0 0.0 4.0 2 1 1 3 3 3 3 RNA methyltransferase MTS PF05175.14 PFH38540.1 - 1.1e-06 28.4 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PFH38540.1 - 0.05 14.3 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fz PF01392.22 PFH38541.1 - 0.016 15.9 0.3 0.046 14.3 0.3 1.8 1 0 0 1 1 1 0 Fz domain MBOAT PF03062.19 PFH38542.1 - 3.6e-22 79.2 22.3 3.6e-22 79.2 22.3 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 PFH38542.1 - 3e-05 24.2 3.8 0.00022 21.4 3.8 2.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family AD PF09793.9 PFH38543.1 - 1.5e-17 63.5 0.1 4.1e-17 62.1 0.0 1.7 1 1 1 2 2 2 1 Anticodon-binding domain Ribosomal_S3Ae PF01015.18 PFH38544.1 - 4.6e-93 310.4 0.2 5.6e-93 310.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Bul1_C PF04426.12 PFH38544.1 - 0.07 12.5 0.2 0.091 12.2 0.2 1.2 1 0 0 1 1 1 0 Bul1 C terminus TPT PF03151.16 PFH38546.1 - 4.1e-13 49.3 25.7 5.3e-13 49.0 25.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PFH38546.1 - 0.058 13.6 39.5 0.29 11.3 13.5 2.3 2 0 0 2 2 2 0 EamA-like transporter family HipN PF18253.1 PFH38549.1 - 1.1e-15 57.0 0.0 3.5e-15 55.4 0.0 1.9 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain STI1 PF17830.1 PFH38549.1 - 4.3e-13 49.0 0.1 1.3e-12 47.5 0.2 1.7 2 0 0 2 2 2 1 STI1 domain TPR_1 PF00515.28 PFH38549.1 - 6.9e-09 35.2 2.8 5.4e-05 22.8 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PFH38549.1 - 3.5e-06 26.6 0.4 0.048 13.4 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 PFH38549.1 - 1.1e-05 25.1 12.2 0.0018 18.2 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 PFH38549.1 - 0.0057 16.9 0.5 0.059 13.8 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PFH38549.1 - 0.023 14.8 0.6 0.13 12.5 0.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PFH38549.1 - 0.075 13.6 1.2 0.25 11.9 0.4 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 PFH38549.1 - 0.081 13.8 0.1 0.081 13.8 0.1 3.0 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 PFH38549.1 - 0.28 11.9 0.3 0.28 11.9 0.3 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat XRN_M PF17846.1 PFH38549.1 - 0.51 9.2 2.8 0.86 8.5 2.8 1.3 1 0 0 1 1 1 0 Xrn1 helical domain TPR_12 PF13424.6 PFH38549.1 - 0.57 10.5 0.0 0.57 10.5 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat FKBP_N PF01346.18 PFH38549.1 - 0.64 11.0 5.9 2.4 9.1 4.8 2.3 3 0 0 3 3 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Chs7 PF12271.8 PFH38550.1 - 0.0032 16.9 3.0 0.0041 16.5 3.0 1.1 1 0 0 1 1 1 1 Chitin synthase export chaperone Polysacc_synt_C PF14667.6 PFH38550.1 - 1 9.4 12.6 0.3 11.2 9.9 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain EELM2 PF15863.5 PFH38551.1 - 1.9e-74 249.5 0.1 2.7e-74 249.0 0.1 1.2 1 0 0 1 1 1 1 Extended EGL-27 and MTA1 homology domain PHD PF00628.29 PFH38551.1 - 3.8e-05 23.5 9.2 0.00015 21.6 9.2 2.1 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 PFH38551.1 - 0.25 11.3 5.1 0.88 9.5 5.1 2.0 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 PFH38551.1 - 5.4 7.2 12.6 2.1 8.5 8.0 2.7 2 0 0 2 2 2 0 PHD-finger PTS_2-RNA PF01885.16 PFH38552.1 - 0.00033 20.8 0.0 0.00033 20.8 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DSPc PF00782.20 PFH38554.1 - 0.0035 17.1 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTEN_C2 PF10409.9 PFH38554.1 - 0.0059 16.4 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain of PTEN tumour-suppressor protein NuA4 PF09340.10 PFH38555.1 - 8e-20 70.5 0.0 1.5e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Patatin PF01734.22 PFH38556.1 - 3.4e-12 47.0 0.3 2.9e-11 44.0 0.2 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase GCS PF03074.16 PFH38557.1 - 9.3e-103 344.4 0.0 4.1e-53 181.1 0.0 3.2 3 0 0 3 3 3 3 Glutamate-cysteine ligase AMP-binding PF00501.28 PFH38558.1 - 1.7e-78 264.2 0.0 2.2e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PFH38558.1 - 7.8e-23 81.2 1.3 2.6e-22 79.6 1.2 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 PFH38558.1 - 9.7e-19 67.0 0.9 1.1e-17 63.6 0.1 2.6 2 1 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 PFH38558.1 - 0.066 13.2 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) GHL5 PF14872.6 PFH38560.1 - 0.082 10.9 0.4 0.098 10.7 0.4 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Allexi_40kDa PF05549.11 PFH38560.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein FAD_binding_3 PF01494.19 PFH38561.1 - 3.8e-42 144.8 1.6 9e-18 64.6 0.0 4.2 3 1 1 4 4 4 3 FAD binding domain Pyr_redox_3 PF13738.6 PFH38561.1 - 0.0023 17.3 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PFH38561.1 - 0.0043 16.7 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 PFH38561.1 - 0.009 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_8 PF13450.6 PFH38561.1 - 0.017 15.3 0.0 0.054 13.7 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PFH38561.1 - 0.02 15.4 0.0 0.046 14.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PFH38561.1 - 0.034 13.4 0.0 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SUV3_C PF12513.8 PFH38562.1 - 9.7e-14 51.0 0.9 1.8e-13 50.2 0.9 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 PFH38562.1 - 4.6e-06 26.9 0.0 0.0045 17.3 0.0 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 PFH38562.1 - 0.026 14.4 0.1 0.057 13.3 0.1 1.6 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 Brix PF04427.18 PFH38564.1 - 3e-33 115.5 0.0 4.2e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain zf-UBP PF02148.19 PFH38565.1 - 0.0031 17.8 0.7 0.011 16.1 0.1 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein GAS PF13851.6 PFH38565.1 - 0.0078 15.6 12.3 0.018 14.4 12.3 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 PFH38565.1 - 0.0079 15.8 4.0 0.012 15.2 4.0 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit Snapin_Pallidin PF14712.6 PFH38565.1 - 0.0087 16.5 3.9 0.0087 16.5 3.9 2.5 1 1 1 2 2 2 1 Snapin/Pallidin UPF0242 PF06785.11 PFH38565.1 - 0.015 15.4 12.3 0.026 14.6 12.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Allexi_40kDa PF05549.11 PFH38565.1 - 0.066 12.7 2.7 0.11 12.0 2.7 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein CENP-Q PF13094.6 PFH38565.1 - 0.072 13.3 13.9 0.18 12.0 13.9 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit IFT57 PF10498.9 PFH38565.1 - 0.073 12.0 7.7 0.12 11.3 7.7 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 V_ATPase_I PF01496.19 PFH38565.1 - 0.088 10.7 7.5 0.13 10.2 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.6 PFH38565.1 - 0.1 11.2 8.7 0.16 10.6 8.7 1.1 1 0 0 1 1 1 0 AAA domain HAUS-augmin3 PF14932.6 PFH38565.1 - 0.13 11.9 16.3 0.012 15.2 11.9 1.5 2 0 0 2 2 1 0 HAUS augmin-like complex subunit 3 Filament PF00038.21 PFH38565.1 - 0.16 11.5 19.2 0.25 10.9 18.0 1.7 1 1 1 2 2 2 0 Intermediate filament protein Tam41_Mmp37 PF09139.11 PFH38565.1 - 0.18 11.2 3.4 0.26 10.7 3.4 1.1 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial FapA PF03961.13 PFH38565.1 - 0.19 10.3 6.2 0.28 9.8 6.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Golgin_A5 PF09787.9 PFH38565.1 - 0.2 11.1 13.8 0.34 10.3 13.8 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 PHM7_cyt PF14703.6 PFH38565.1 - 0.33 11.2 4.0 0.6 10.3 4.0 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter TMF_TATA_bd PF12325.8 PFH38565.1 - 0.37 11.0 13.7 0.82 9.9 13.7 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Fmp27_WPPW PF10359.9 PFH38565.1 - 0.48 9.2 5.5 0.72 8.6 5.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spc7 PF08317.11 PFH38565.1 - 0.59 9.0 17.8 1.3 7.8 17.8 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Troponin PF00992.20 PFH38565.1 - 0.64 10.3 15.9 0.049 13.9 9.6 2.2 2 0 0 2 2 2 0 Troponin FemAB PF02388.16 PFH38565.1 - 0.64 8.8 4.5 0.97 8.2 4.5 1.3 1 0 0 1 1 1 0 FemAB family Atg14 PF10186.9 PFH38565.1 - 0.68 9.0 7.2 1.1 8.3 7.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 EST1 PF10374.9 PFH38565.1 - 1.1 9.9 3.1 2.5 8.7 0.1 2.2 1 1 1 2 2 2 0 Telomerase activating protein Est1 Laminin_II PF06009.12 PFH38565.1 - 1.1 9.2 10.4 2 8.4 10.4 1.4 1 0 0 1 1 1 0 Laminin Domain II CREPT PF16566.5 PFH38565.1 - 1.6 8.9 12.2 2 8.6 11.2 1.6 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour NPV_P10 PF05531.12 PFH38565.1 - 1.7 9.1 6.1 11 6.5 6.1 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-ZPR1 PF03367.13 PFH38565.1 - 1.9 8.3 5.7 1.6 8.6 4.1 1.6 2 0 0 2 2 1 0 ZPR1 zinc-finger domain PCRF PF03462.18 PFH38565.1 - 1.9 8.3 10.3 3.4 7.5 10.3 1.3 1 0 0 1 1 1 0 PCRF domain DUF4472 PF14739.6 PFH38565.1 - 2.1 9.1 14.7 1.8 9.4 10.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) YabA PF06156.13 PFH38565.1 - 2.7 8.7 9.8 16 6.2 9.7 2.1 1 1 0 1 1 1 0 Initiation control protein YabA Ima1_N PF09779.9 PFH38565.1 - 2.9 8.7 5.7 20 6.0 0.0 3.2 3 0 0 3 3 3 0 Ima1 N-terminal domain FUSC PF04632.12 PFH38565.1 - 3.5 6.0 15.2 6 5.3 15.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.8 PFH38565.1 - 4 6.7 20.0 14 4.9 20.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ERM PF00769.19 PFH38565.1 - 4.3 7.1 24.9 0.11 12.3 18.4 1.6 2 0 0 2 2 1 0 Ezrin/radixin/moesin family DUF2203 PF09969.9 PFH38565.1 - 5.2 7.8 12.3 27 5.5 12.3 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) APG6_N PF17675.1 PFH38565.1 - 5.3 7.6 23.3 36 4.9 23.3 2.4 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF724 PF05266.14 PFH38565.1 - 9.6 6.0 12.0 17 5.2 12.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BRAP2 PF07576.12 PFH38566.1 - 1.2e-08 35.1 0.0 2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 BRCA1-associated protein 2 INCENP_ARK-bind PF03941.15 PFH38567.1 - 0.016 15.1 0.0 0.071 13.1 0.0 2.2 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region G6PD_bact PF10786.9 PFH38567.1 - 0.099 12.2 0.9 0.18 11.3 0.9 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) SNF2_N PF00176.23 PFH38568.1 - 5.8e-58 196.3 0.0 1.7e-57 194.8 0.0 1.8 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PFH38568.1 - 2.1e-14 53.8 0.0 5.2e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PFH38568.1 - 1.3e-09 38.3 0.0 4.1e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PFH38568.1 - 4.5e-06 26.6 0.0 7.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 PFH38568.1 - 0.00027 20.2 0.0 0.00084 18.6 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.9 PFH38568.1 - 0.0042 16.4 0.0 0.01 15.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 PFH38568.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DUF2799 PF10973.8 PFH38568.1 - 0.14 12.6 0.1 33 5.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2799) UPF0242 PF06785.11 PFH38569.1 - 0.014 15.5 7.2 0.014 15.5 7.2 4.0 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF3107 PF11305.8 PFH38569.1 - 0.33 11.2 2.8 25 5.2 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) Baculo_PEP_C PF04513.12 PFH38569.1 - 8.8 6.4 8.2 27 4.8 0.2 3.6 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FPP PF05911.11 PFH38570.1 - 0.0072 14.6 6.5 0.01 14.1 6.5 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil RPW8 PF05659.11 PFH38570.1 - 0.014 15.1 0.8 0.031 14.0 0.3 1.7 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Syntaxin PF00804.25 PFH38570.1 - 0.024 14.3 5.8 0.04 13.6 5.8 1.3 1 0 0 1 1 1 0 Syntaxin KIP1 PF07765.12 PFH38570.1 - 0.11 12.6 4.4 0.088 12.9 1.1 2.1 1 1 1 2 2 2 0 KIP1-like protein Mt_ATP_synt PF15704.5 PFH38570.1 - 0.12 12.3 4.5 0.2 11.5 4.4 1.4 1 1 0 1 1 1 0 Mitochondrial ATP synthase subunit CENP-F_leu_zip PF10473.9 PFH38570.1 - 0.15 12.0 10.6 0.4 10.7 10.6 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 PFH38570.1 - 0.62 10.4 3.5 1.2 9.5 0.2 2.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 PFH38570.1 - 0.64 8.8 12.5 0.95 8.3 12.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 PFH38570.1 - 1.9 7.5 10.9 3 6.9 10.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ERM PF00769.19 PFH38570.1 - 2.1 8.1 18.4 0.04 13.7 10.8 1.8 2 0 0 2 2 2 0 Ezrin/radixin/moesin family GAS PF13851.6 PFH38570.1 - 2.9 7.2 13.3 4.2 6.7 12.6 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 PFH38570.1 - 2.9 6.4 4.0 4 5.9 4.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 PFH38570.1 - 3.3 7.8 8.8 5.9 6.9 8.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 PFH38570.1 - 5.1 6.2 4.5 7.4 5.7 4.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein T3SSipB PF16535.5 PFH38570.1 - 5.7 7.4 8.3 1.7 9.1 3.8 2.2 2 0 0 2 2 2 0 Type III cell invasion protein SipB Thioredoxin_8 PF13905.6 PFH38572.1 - 7e-24 84.0 0.0 1.1e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 PFH38572.1 - 0.00046 20.1 0.0 0.0007 19.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PFH38572.1 - 0.0029 17.3 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 PFH38572.1 - 0.003 17.5 0.0 0.0045 16.9 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC RTC PF01137.21 PFH38573.1 - 2.1e-46 157.9 0.1 2.6e-46 157.6 0.1 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 PFH38573.1 - 2.5e-26 92.2 0.1 8.8e-26 90.4 0.1 1.9 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain WD40 PF00400.32 PFH38574.1 - 5.5e-22 77.7 29.0 4e-06 27.5 0.2 11.4 12 2 0 12 12 12 5 WD domain, G-beta repeat Utp12 PF04003.12 PFH38574.1 - 2.7e-05 24.4 0.9 0.00014 22.2 0.9 2.1 1 1 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 PFH38574.1 - 3.9e-05 23.9 0.2 6.1 7.2 0.0 5.6 5 1 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PFH38574.1 - 0.012 14.2 0.2 2 7.0 0.1 3.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Frtz PF11768.8 PFH38574.1 - 0.016 13.5 0.1 4.9 5.4 0.0 3.0 3 1 1 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 PFH38574.1 - 0.23 10.4 0.1 7.6 5.4 0.0 3.2 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-CW PF07496.15 PFH38575.1 - 4.4e-23 81.0 23.9 7e-13 48.4 8.2 3.3 3 0 0 3 3 3 2 CW-type Zinc Finger SPX PF03105.19 PFH38575.1 - 2.5 7.9 4.1 8 6.3 4.1 1.9 1 0 0 1 1 1 0 SPX domain Ldh_1_N PF00056.23 PFH38576.1 - 7.1e-38 129.9 0.1 1.1e-37 129.3 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 PFH38576.1 - 1e-30 106.9 0.0 2.4e-30 105.7 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 PFH38576.1 - 6.6e-06 25.8 0.8 0.0065 16.0 0.3 2.4 2 0 0 2 2 2 2 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.19 PFH38576.1 - 0.0062 15.6 0.0 0.014 14.4 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1079 PF06435.11 PFH38576.1 - 0.066 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) 3HCDH_N PF02737.18 PFH38576.1 - 0.082 12.8 0.8 0.25 11.2 0.8 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PP2C PF00481.21 PFH38577.1 - 2.3e-60 204.4 2.9 3.5e-54 184.2 0.2 3.3 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 PFH38577.1 - 0.0046 16.9 0.1 0.024 14.5 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) SAPS PF04499.15 PFH38577.1 - 4.1 6.1 6.2 6.6 5.4 6.2 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Exo_endo_phos PF03372.23 PFH38579.1 - 1.1e-05 25.0 0.0 5.1e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_S3_C PF00189.20 PFH38580.1 - 1.1e-23 83.5 0.8 3.1e-23 82.1 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 PFH38580.1 - 4.7e-10 39.2 0.0 7.6e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 KH domain IMP2_N PF18590.1 PFH38581.1 - 9.3e-11 42.1 0.0 1.8e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain Gal_Lectin PF02140.18 PFH38581.1 - 1.3e-05 25.6 0.1 1.3e-05 25.6 0.1 2.6 3 0 0 3 3 3 1 Galactose binding lectin domain PBP_sp32 PF07222.12 PFH38581.1 - 0.18 11.2 7.3 0.33 10.4 7.3 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Presenilin PF01080.17 PFH38581.1 - 0.64 8.7 2.4 0.92 8.2 2.4 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 PFH38581.1 - 0.92 8.7 2.2 1.3 8.1 2.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mitofilin PF09731.9 PFH38581.1 - 1.3 7.8 14.5 2 7.2 14.5 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CDC45 PF02724.14 PFH38581.1 - 3.2 5.9 6.7 4.2 5.5 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein His_Phos_2 PF00328.22 PFH38582.1 - 0.0052 16.2 0.0 0.28 10.5 0.0 2.9 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 2) Myosin_head PF00063.21 PFH38584.1 - 8.5e-178 592.7 0.0 1e-177 592.4 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 PFH38584.1 - 0.0085 16.4 0.9 0.044 14.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 PFH38584.1 - 0.015 15.7 0.6 0.1 13.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 PFH38584.1 - 0.082 12.0 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 PFH38584.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 PFH38584.1 - 0.15 12.6 0.0 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Catalase PF00199.19 PFH38585.1 - 2.4e-196 652.4 0.2 2.8e-196 652.1 0.2 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 PFH38585.1 - 3.4e-22 78.4 0.1 8.6e-22 77.1 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive zf-SNAP50_C PF12251.8 PFH38586.1 - 3.6e-27 95.3 0.1 3.7e-21 75.7 0.2 2.2 2 0 0 2 2 2 2 snRNA-activating protein of 50kDa MW C terminal Romo1 PF10247.9 PFH38586.1 - 0.25 11.7 0.2 0.51 10.7 0.2 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Ribosomal_L7Ae PF01248.26 PFH38587.1 - 6.5e-24 83.5 0.1 7.6e-24 83.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 PFH38587.1 - 0.022 14.8 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase APP_Cu_bd PF12924.7 PFH38587.1 - 0.034 14.9 0.0 0.052 14.3 0.0 1.4 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD DPBB_1 PF03330.18 PFH38587.1 - 0.1 12.9 0.1 2.7 8.3 0.0 2.1 1 1 1 2 2 2 0 Lytic transglycolase SWIB PF02201.18 PFH38588.1 - 1.6e-11 43.9 0.0 2.6e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain SAM_1 PF00536.30 PFH38588.1 - 1.6e-05 25.3 0.0 2.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PFH38588.1 - 0.0017 18.5 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TFIIA PF03153.13 PFH38589.1 - 6.7e-05 23.1 0.2 9.9e-05 22.5 0.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Sec7 PF01369.20 PFH38591.1 - 6.2e-67 224.8 0.0 1.1e-66 224.0 0.0 1.4 1 1 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 PFH38591.1 - 2.8e-09 37.1 0.0 1.2e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal PIG-S PF10510.9 PFH38593.1 - 4.9e-29 101.6 2.7 2.4e-12 46.5 0.0 4.2 3 1 0 3 3 3 3 Phosphatidylinositol-glycan biosynthesis class S protein zf-RING_2 PF13639.6 PFH38595.1 - 2.5e-11 43.7 11.3 9.4e-11 41.9 11.3 2.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PFH38595.1 - 1.9e-08 33.9 8.2 1.9e-08 33.9 8.2 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PFH38595.1 - 1.7e-07 31.0 8.8 4.2e-07 29.7 8.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH38595.1 - 1.2e-05 25.3 6.4 2.8e-05 24.1 6.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PFH38595.1 - 1.4e-05 24.8 8.8 3.2e-05 23.7 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PFH38595.1 - 1.6e-05 25.1 10.2 7.7e-05 22.9 10.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PFH38595.1 - 0.0021 18.0 9.1 0.0053 16.7 9.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 PFH38595.1 - 0.009 15.6 5.6 0.009 15.6 5.6 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 PFH38595.1 - 0.014 15.5 3.2 0.037 14.2 3.2 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain Vps39_2 PF10367.9 PFH38595.1 - 0.031 14.7 0.3 0.052 14.0 0.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-ANAPC11 PF12861.7 PFH38595.1 - 0.073 13.1 5.5 0.24 11.5 5.5 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.11 PFH38595.1 - 0.2 11.6 0.2 0.37 10.8 0.2 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.7 PFH38595.1 - 0.34 11.1 9.6 1.1 9.4 9.6 2.0 1 0 0 1 1 1 0 RING-variant domain NumbF PF06311.12 PFH38596.1 - 0.078 13.5 8.3 6 7.5 0.1 3.1 2 0 0 2 2 2 0 NUMB domain YojJ PF10372.9 PFH38596.1 - 3.1 8.0 13.2 4.7 7.4 0.4 4.8 2 1 1 4 4 4 0 Bacterial membrane-spanning protein N-terminus Phage_tail_APC PF16778.5 PFH38596.1 - 7.6 6.5 8.0 1.8 8.5 0.1 3.3 2 0 0 2 2 2 0 Phage tail assembly chaperone protein ATG16 PF08614.11 PFH38596.1 - 9.3 6.4 97.1 0.39 10.9 18.4 4.8 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Reg_prop PF07494.11 PFH38598.1 - 5.6e-06 25.9 0.3 0.76 10.2 0.0 4.0 4 0 0 4 4 4 3 Two component regulator propeller PSII_BNR PF14870.6 PFH38598.1 - 8.8e-05 21.9 1.8 0.00048 19.5 0.2 2.1 1 1 1 2 2 2 1 Photosynthesis system II assembly factor YCF48 RSN1_7TM PF02714.15 PFH38599.1 - 1e-26 93.9 23.3 1.8e-26 93.1 23.3 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PFH38599.1 - 0.00021 21.1 0.1 0.00021 21.1 0.1 3.2 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport SpoIIIAC PF06686.11 PFH38599.1 - 0.24 11.6 0.8 0.76 10.0 0.8 1.8 1 0 0 1 1 1 0 Stage III sporulation protein AC/AD protein family RAP PF08373.10 PFH38600.1 - 3e-09 36.8 0.0 7.9e-08 32.3 0.0 2.4 2 0 0 2 2 2 1 RAP domain MTES_1575 PF18741.1 PFH38600.1 - 2.5e-05 24.4 0.3 0.081 13.1 0.3 2.6 2 0 0 2 2 2 2 REase_MTES_1575 3HCDH_N PF02737.18 PFH38601.1 - 1.2e-46 158.9 0.1 5.4e-35 120.9 0.0 2.1 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 PFH38601.1 - 6.8e-35 119.6 0.0 1.2e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Methyltransf_25 PF13649.6 PFH38601.1 - 0.079 13.7 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Chorein_N PF12624.7 PFH38602.1 - 2.6e-11 43.6 0.0 8.8e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 PFH38602.1 - 3.6e-07 30.1 0.0 7.5e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 PFH38602.1 - 0.04 13.7 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal RESP18 PF14948.6 PFH38602.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.8 1 0 0 1 1 1 0 RESP18 domain SHR-BD PF06650.12 PFH38602.1 - 0.23 10.8 0.4 1.1 8.6 0.0 2.2 4 0 0 4 4 4 0 SHR-binding domain of vacuolar-sorting associated protein 13 Peptidase_S58 PF03576.14 PFH38603.1 - 1.3e-18 67.6 7.5 1e-13 51.5 1.7 3.2 3 0 0 3 3 3 3 Peptidase family S58 DnaJ PF00226.31 PFH38604.1 - 1e-14 54.3 0.0 3.4e-14 52.7 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_6 PF13848.6 PFH38604.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Tim54 PF11711.8 PFH38604.1 - 0.033 13.0 0.1 0.85 8.3 1.8 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 TFB6 PF17110.5 PFH38604.1 - 0.96 9.2 3.6 0.68 9.7 0.9 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH SHR3_chaperone PF08229.11 PFH38604.1 - 1.3 7.9 3.3 19 4.2 0.1 2.6 2 0 0 2 2 2 0 ER membrane protein SH3 Pox_Ag35 PF03286.14 PFH38604.1 - 2.9 7.6 10.9 3.1 7.6 7.6 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 PFH38604.1 - 3.6 7.6 12.2 5.8 6.9 7.0 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 PFH38604.1 - 7.2 6.3 12.6 8.8 6.0 6.3 3.2 3 0 0 3 3 3 0 FAM176 family CDC45 PF02724.14 PFH38604.1 - 8.4 4.5 10.6 0.4 8.9 3.6 2.0 2 0 0 2 2 2 0 CDC45-like protein CDC50 PF03381.15 PFH38606.1 - 1.9e-47 162.1 0.0 2.7e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Adipogenin PF15202.6 PFH38606.1 - 0.91 9.6 3.4 9.7 6.3 0.1 2.9 3 0 0 3 3 3 0 Adipogenin Atg14 PF10186.9 PFH38607.1 - 5.9 5.9 9.4 10 5.1 9.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PP2C PF00481.21 PFH38608.1 - 8.2e-50 169.8 0.4 6.6e-25 88.2 0.2 3.3 3 0 0 3 3 3 3 Protein phosphatase 2C FHA PF00498.26 PFH38608.1 - 0.0039 17.5 0.0 0.0097 16.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain ABC_trans_N PF14510.6 PFH38609.1 - 0.0089 16.6 1.0 0.13 12.9 0.0 2.7 3 0 0 3 3 3 1 ABC-transporter N-terminal DUF2834 PF11196.8 PFH38610.1 - 0.08 13.3 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) CCDC66 PF15236.6 PFH38611.1 - 0.043 13.7 4.1 0.11 12.3 4.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 PROCN PF08083.11 PFH38612.1 - 2.3e-230 764.3 8.3 4e-230 763.5 8.3 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 PFH38612.1 - 1.5e-125 417.4 1.6 2.4e-125 416.7 1.6 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 PFH38612.1 - 2.4e-87 290.8 2.5 6e-87 289.6 2.5 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 PFH38612.1 - 5.3e-87 289.4 4.0 5.3e-87 289.4 4.0 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 PFH38612.1 - 1.9e-72 241.6 0.0 4.1e-72 240.6 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 PFH38612.1 - 3.8e-53 178.6 0.0 7.3e-53 177.7 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 PFH38612.1 - 6.8e-47 157.7 0.4 2.1e-46 156.2 0.4 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 PFH38612.1 - 2e-05 24.6 0.0 4.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PilX_N PF14341.6 PFH38613.1 - 0.059 13.3 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 PilX N-terminal ThiF PF00899.21 PFH38617.1 - 7.7e-46 156.4 0.3 1.6e-45 155.4 0.3 1.4 1 1 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 PFH38617.1 - 9.5e-05 22.7 0.1 0.57 10.5 0.0 2.6 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 PFH38617.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 PFH38617.1 - 0.031 14.7 0.1 0.12 12.8 0.1 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 PFH38617.1 - 0.062 12.5 0.3 0.092 12.0 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 PFH38617.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-C3HC4_2 PF13923.6 PFH38618.1 - 5.3e-07 29.4 11.5 5.3e-07 29.4 11.5 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PFH38618.1 - 6.2e-07 29.2 8.5 6.2e-07 29.2 8.5 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PFH38618.1 - 0.00013 21.9 7.2 0.00013 21.9 7.2 3.2 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 PFH38618.1 - 0.00051 20.3 11.6 0.00051 20.3 11.6 3.5 3 0 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 PFH38618.1 - 0.00087 19.1 11.3 0.00087 19.1 11.3 4.3 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PFH38618.1 - 0.0022 17.9 10.3 0.0022 17.9 10.3 3.4 3 0 0 3 3 3 1 zinc-RING finger domain PRP21_like_P PF12230.8 PFH38618.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-CRD PF17979.1 PFH38618.1 - 2.5 8.2 12.1 8.4 6.5 3.5 2.7 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions adh_short PF00106.25 PFH38619.1 - 1.2e-16 60.8 0.0 2.1e-16 60.0 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PFH38619.1 - 3.8e-09 36.4 0.3 9.7e-09 35.1 0.3 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CobW_C PF07683.14 PFH38619.1 - 0.085 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Thioredoxin PF00085.20 PFH38620.1 - 8.4e-09 35.3 0.0 1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 PFH38620.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin T4bSS_IcmS PF12608.8 PFH38620.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Type IVb secretion, IcmS, effector-recruitment ATP-synt PF00231.19 PFH38622.1 - 2.1e-76 257.3 0.5 2.4e-76 257.2 0.5 1.0 1 0 0 1 1 1 1 ATP synthase Acyl-CoA_dh_1 PF00441.24 PFH38623.1 - 7e-30 104.2 3.0 1.1e-29 103.6 3.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 PFH38623.1 - 1.8e-20 72.9 0.0 3.3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 PFH38623.1 - 1.5e-15 57.8 0.1 3.7e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 PFH38623.1 - 7.6e-07 29.5 0.3 1.3e-06 28.8 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 PFH38623.1 - 0.0033 18.0 0.0 0.0069 16.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal ACP_syn_III_C PF08541.10 PFH38624.1 - 2e-37 127.2 0.1 1.1e-36 124.8 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 PFH38624.1 - 3.5e-24 84.5 0.0 9.2e-24 83.1 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_C PF02797.15 PFH38624.1 - 0.00052 20.0 0.0 0.00085 19.3 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Thiolase_C PF02803.18 PFH38624.1 - 0.05 13.3 0.2 0.83 9.3 0.0 2.7 3 0 0 3 3 3 0 Thiolase, C-terminal domain MspA PF09203.11 PFH38625.1 - 0.36 10.7 15.4 1.8e+04 -4.8 15.3 4.2 1 1 0 1 1 1 0 MspA Trypan_PARP PF05887.11 PFH38625.1 - 4.7 7.2 57.6 13 5.8 11.6 5.6 2 1 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) TPR_1 PF00515.28 PFH38626.1 - 7.7e-20 69.8 0.6 3.7e-08 32.8 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 PFH38626.1 - 9.6e-19 65.9 5.8 2e-06 27.4 0.0 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 PFH38626.1 - 1.4e-11 43.8 2.8 0.00032 20.3 0.0 4.9 2 2 2 4 4 4 4 TPR repeat TPR_8 PF13181.6 PFH38626.1 - 4.8e-11 42.0 0.2 2.2e-06 27.4 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 PFH38626.1 - 2.3e-10 40.8 12.7 3.3e-06 27.5 1.4 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 PFH38626.1 - 1e-09 38.9 7.8 7.5e-08 32.9 0.8 6.1 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 PFH38626.1 - 2e-09 37.2 10.7 0.0002 21.5 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 PFH38626.1 - 2.4e-07 30.3 3.5 5e-05 23.0 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 PFH38626.1 - 4.4e-06 26.7 5.1 0.00074 19.6 0.2 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 PFH38626.1 - 1.1e-05 25.9 5.6 0.0039 17.9 0.5 7.8 6 2 3 9 9 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 PFH38626.1 - 1.1e-05 25.6 8.1 0.019 15.2 0.2 4.2 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 PFH38626.1 - 0.0041 16.9 6.9 0.023 14.6 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 PFH38626.1 - 0.036 14.5 0.7 0.036 14.5 0.7 4.4 3 1 0 3 3 3 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 PFH38626.1 - 0.041 14.1 1.6 15 5.9 0.0 3.7 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PFH38626.1 - 0.25 12.0 7.0 5.7 7.8 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat PP2C PF00481.21 PFH38628.1 - 1.1e-32 113.8 0.0 1.5e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Pet127 PF08634.10 PFH38628.1 - 0.0077 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 PP2C_2 PF13672.6 PFH38628.1 - 0.032 13.8 0.0 0.58 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C CALCOCO1 PF07888.11 PFH38629.1 - 0.018 14.0 39.2 0.029 13.2 39.2 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CagE_TrbE_VirB PF03135.14 PFH38629.1 - 0.11 12.5 0.5 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system ApoO PF09769.9 PFH38629.1 - 0.95 9.4 10.3 1.5 8.8 1.6 3.0 2 1 1 3 3 3 0 Apolipoprotein O DUF948 PF06103.11 PFH38629.1 - 1 9.6 8.1 28 5.0 8.1 2.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 PFH38629.1 - 4.2 7.4 6.0 17 5.4 0.8 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_11 PF13086.6 PFH38630.1 - 1e-52 179.5 26.0 2.5e-34 119.2 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_12 PF13087.6 PFH38630.1 - 1.5e-48 165.1 0.0 2.8e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PFH38630.1 - 9.2e-11 41.8 11.3 2.1e-07 30.9 0.1 3.6 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.6 PFH38630.1 - 1.1e-10 42.0 0.0 9.8e-10 38.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 PFH38630.1 - 0.0014 18.4 0.2 0.22 11.3 0.0 3.5 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase Helicase_C_2 PF13307.6 PFH38631.1 - 2.7e-39 135.1 0.0 2.5e-32 112.4 0.0 2.8 2 1 0 2 2 2 2 Helicase C-terminal domain DEAD_2 PF06733.15 PFH38631.1 - 5.7e-23 81.4 1.1 8.7e-16 58.0 0.0 3.1 3 0 0 3 3 3 2 DEAD_2 DEAD PF00270.29 PFH38631.1 - 1.7e-05 24.7 0.2 7.2e-05 22.6 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 PFH38631.1 - 0.00046 20.2 0.1 0.0018 18.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PFH38631.1 - 0.00047 19.9 0.1 0.0013 18.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PFH38631.1 - 0.0049 16.0 0.0 0.0085 15.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_11 PF13086.6 PFH38631.1 - 0.031 14.1 0.1 0.031 14.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 PFH38631.1 - 0.043 13.3 0.2 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 PFH38631.1 - 0.046 14.1 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Tubulin PF00091.25 PFH38634.1 - 2.1e-64 217.4 0.0 4.1e-64 216.4 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PFH38634.1 - 1.1e-45 154.8 0.1 2e-45 154.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 PFH38634.1 - 0.024 14.3 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Macro PF01661.21 PFH38635.1 - 5.3e-10 39.4 0.0 1.1e-06 28.7 0.0 2.5 2 0 0 2 2 2 2 Macro domain IMCp PF12314.8 PFH38636.1 - 2e-30 104.9 63.6 4.9e-29 100.5 43.6 5.1 3 2 1 4 4 4 2 Inner membrane complex protein IMCp PF12314.8 PFH38637.1 - 3.3e-31 107.4 100.6 8.3e-19 67.7 36.3 5.0 1 1 4 5 5 5 5 Inner membrane complex protein ATP-gua_Ptrans PF00217.19 PFH38638.1 - 2.3e-32 112.2 0.0 1.8e-16 60.3 0.0 3.3 3 0 0 3 3 3 3 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 PFH38638.1 - 0.1 13.0 0.0 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 ATP:guanido phosphotransferase, N-terminal domain HEAT PF02985.22 PFH38640.1 - 1.5e-11 43.5 21.1 0.00028 20.9 0.0 9.8 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.6 PFH38640.1 - 2.8e-10 40.5 32.6 0.0074 16.8 0.2 12.0 12 0 0 12 12 12 3 HEAT-like repeat HEAT_2 PF13646.6 PFH38640.1 - 7.5e-10 39.1 20.3 4.1e-05 23.9 0.3 7.5 7 1 1 8 8 8 3 HEAT repeats Cnd1 PF12717.7 PFH38640.1 - 0.00026 21.1 4.7 0.0012 19.0 0.0 3.9 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 PFH38640.1 - 0.00095 19.1 4.1 2.9 8.1 0.2 4.8 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 PFH38640.1 - 0.0016 18.3 0.5 0.016 15.1 0.2 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Importin_rep_4 PF18808.1 PFH38640.1 - 0.0043 17.3 5.6 0.12 12.7 0.0 5.7 7 0 0 7 7 7 1 Importin repeat Inj_translocase PF16928.5 PFH38640.1 - 0.88 9.0 3.8 2.8 7.4 0.0 2.6 2 1 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome SGS PF05002.15 PFH38641.1 - 3.2e-31 107.3 1.4 6.4e-31 106.3 1.4 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.16 PFH38641.1 - 1.3e-10 42.2 0.0 5.6e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 CS domain HEAT PF02985.22 PFH38642.1 - 7.7e-16 56.8 44.6 0.0017 18.5 0.0 18.8 20 0 0 20 20 20 4 HEAT repeat HEAT_2 PF13646.6 PFH38642.1 - 1.7e-14 53.9 51.8 0.0055 17.1 0.0 14.1 9 3 6 16 16 15 9 HEAT repeats HEAT_EZ PF13513.6 PFH38642.1 - 8.9e-11 42.1 57.6 0.0015 19.0 0.0 17.4 13 4 6 19 19 19 5 HEAT-like repeat Vac14_Fab1_bd PF12755.7 PFH38642.1 - 2.7e-07 31.1 0.0 5.8 7.6 0.0 7.5 6 2 3 9 9 8 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 PFH38642.1 - 2.9e-07 30.7 0.0 15 5.6 0.0 6.8 7 1 0 7 7 7 1 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 PFH38642.1 - 3.2e-07 30.2 0.4 1.7 8.6 0.0 6.4 7 0 0 7 7 7 2 UME (NUC010) domain Adaptin_N PF01602.20 PFH38642.1 - 6.1e-07 28.4 7.0 0.0029 16.2 0.0 5.4 8 0 0 8 8 8 2 Adaptin N terminal region DUF3437 PF11919.8 PFH38642.1 - 0.00041 20.2 3.1 4.5 7.2 0.0 5.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) MMS19_N PF14500.6 PFH38642.1 - 0.04 13.5 9.1 9.6 5.7 0.0 5.8 6 0 0 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II Dymeclin PF09742.9 PFH38642.1 - 0.066 11.6 3.9 0.058 11.8 0.6 2.3 2 0 0 2 2 2 0 Dyggve-Melchior-Clausen syndrome protein ParcG PF10274.9 PFH38642.1 - 0.074 13.2 0.0 1.4e+02 2.5 0.0 4.8 4 0 0 4 4 4 0 Parkin co-regulated protein MMS19_C PF12460.8 PFH38642.1 - 0.77 8.8 12.9 0.17 11.0 0.2 5.4 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal LsmAD PF06741.13 PFH38646.1 - 8.1e-13 48.7 0.1 1.4e-12 47.9 0.1 1.4 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 PFH38646.1 - 7.2e-07 29.3 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain STT3 PF02516.14 PFH38647.1 - 2.2e-90 303.9 39.8 1.2e-89 301.5 39.8 1.8 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit BT1 PF03092.16 PFH38648.1 - 2.9e-53 180.9 18.7 2.1e-31 108.8 8.7 2.8 1 1 0 2 2 2 2 BT1 family TerB PF05099.13 PFH38649.1 - 0.033 14.1 0.1 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 Tellurite resistance protein TerB DUF4435 PF14491.6 PFH38649.1 - 0.041 13.8 0.2 0.083 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) DUF1400 PF07176.11 PFH38649.1 - 0.15 12.4 0.9 0.46 10.8 0.8 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) SPICE PF15678.5 PFH38649.1 - 0.19 11.1 2.2 0.18 11.1 0.5 1.7 1 1 1 2 2 2 0 Centriole duplication and mitotic chromosome congression DUF1269 PF06897.12 PFH38649.1 - 0.67 10.3 2.0 6.6 7.1 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1269) CAP PF00188.26 PFH38650.1 - 3.4e-20 73.2 0.1 5.6e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family XPB_DRD PF18458.1 PFH38650.1 - 0.14 12.1 0.0 0.52 10.2 0.0 2.0 3 0 0 3 3 3 0 Xeroderma pigmentosum group B helicase damage recognition domain Tubulin PF00091.25 PFH38651.1 - 2e-54 184.8 0.0 3.2e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PFH38651.1 - 8.5e-27 93.8 0.0 1.8e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 PFH38651.1 - 0.00046 19.9 0.0 0.0031 17.2 0.0 2.0 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.9 PFH38651.1 - 0.067 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 PFH38651.1 - 0.15 11.2 0.3 0.41 9.8 0.2 1.7 1 1 1 2 2 2 0 Tubulin like Neuromodulin PF06614.11 PFH38653.1 - 0.064 13.4 0.0 0.082 13.1 0.0 1.1 1 0 0 1 1 1 0 Neuromodulin RNA_pol_Rpb4 PF03874.16 PFH38654.1 - 1e-11 45.2 0.1 1.7e-11 44.5 0.1 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF3839 PF12943.7 PFH38654.1 - 0.041 13.3 0.0 0.051 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) Patatin PF01734.22 PFH38655.1 - 1.3e-24 87.5 0.9 1.3e-24 87.5 0.9 4.0 3 1 0 3 3 3 1 Patatin-like phospholipase SIS PF01380.22 PFH38657.1 - 3.6e-36 123.9 0.1 7.3e-21 74.4 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 PFH38657.1 - 5.7e-19 68.6 0.1 1.4e-16 60.9 0.1 2.5 2 0 0 2 2 2 2 Glutamine amidotransferase domain GATase_7 PF13537.6 PFH38657.1 - 8.2e-15 54.8 0.0 1e-08 35.1 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferase domain GATase_4 PF13230.6 PFH38657.1 - 0.00067 18.6 0.1 0.0012 17.8 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II CEBP1_N PF16368.5 PFH38657.1 - 0.29 10.6 6.1 0.54 9.7 6.1 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus WD40 PF00400.32 PFH38658.1 - 7.8e-20 70.9 6.4 1.7e-06 28.6 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PFH38658.1 - 9.7e-14 51.4 0.1 0.00011 22.4 0.0 4.7 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 PFH38658.1 - 4.7e-05 23.2 1.5 6.7 6.8 0.0 4.7 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 PFH38658.1 - 0.032 14.1 0.0 27 4.5 0.0 3.4 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A US30 PF17624.2 PFH38658.1 - 0.075 12.1 0.3 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function Proteasome_A_N PF10584.9 PFH38658.1 - 0.11 12.2 0.2 65 3.3 0.0 4.2 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Ge1_WD40 PF16529.5 PFH38658.1 - 0.12 11.3 0.0 0.55 9.1 0.0 2.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Wzy_C PF04932.15 PFH38659.1 - 0.00092 18.9 1.1 0.012 15.2 0.4 2.2 2 0 0 2 2 2 2 O-Antigen ligase DUF5600 PF18150.1 PFH38660.1 - 4.9e-38 130.0 1.1 9.3e-38 129.1 0.6 1.7 2 0 0 2 2 1 1 Domain of unknown function (DUF5600) EHD_N PF16880.5 PFH38660.1 - 3.6e-14 52.3 0.5 7.9e-14 51.3 0.5 1.6 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 PFH38660.1 - 6.2e-14 52.4 0.0 3.9e-13 49.8 0.0 2.0 1 1 0 1 1 1 1 Dynamin family EF-hand_4 PF12763.7 PFH38660.1 - 1.8e-11 43.9 0.0 5.8e-11 42.3 0.0 1.9 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.23 PFH38660.1 - 1.2e-07 31.8 0.0 2.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PFH38660.1 - 3.1e-05 23.6 0.0 7.7e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 PFH38660.1 - 0.00097 19.3 0.0 0.45 10.7 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PFH38660.1 - 0.0013 18.7 0.1 0.46 10.4 0.0 3.0 2 1 0 2 2 2 1 RsgA GTPase EF-hand_7 PF13499.6 PFH38660.1 - 0.011 16.1 0.0 0.045 14.2 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair PduV-EutP PF10662.9 PFH38660.1 - 0.027 14.2 0.0 1.5 8.6 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 PFH38660.1 - 0.027 14.7 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 PFH38660.1 - 0.05 13.2 0.0 0.78 9.3 0.0 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.12 PFH38660.1 - 0.055 12.8 0.0 0.69 9.2 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 PFH38660.1 - 0.16 11.5 0.0 10 5.6 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B Se-cys_synth_N PF12390.8 PFH38660.1 - 0.17 12.1 0.6 0.6 10.4 0.6 1.9 1 0 0 1 1 1 0 Selenocysteine synthase N terminal STAG PF08514.11 PFH38661.1 - 0.0011 18.8 0.0 0.0011 18.8 0.0 3.5 3 1 1 4 4 4 1 STAG domain ArsA_ATPase PF02374.15 PFH38662.1 - 2.4e-91 306.1 0.1 6.1e-82 275.2 0.0 2.0 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 PFH38662.1 - 7.4e-13 48.8 0.0 8.5e-12 45.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain CbiA PF01656.23 PFH38662.1 - 2.3e-11 43.8 0.3 6.1e-09 36.0 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 PFH38662.1 - 3.3e-06 26.8 0.0 6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 PFH38662.1 - 3.2e-05 23.5 0.2 0.00039 19.9 0.0 2.2 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 PFH38662.1 - 7.1e-05 22.4 0.0 0.00065 19.2 0.0 2.1 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 PFH38662.1 - 0.00014 21.6 0.2 0.002 17.8 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 PFH38662.1 - 0.00021 20.6 0.1 0.018 14.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.22 PFH38662.1 - 0.013 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 PFH38662.1 - 0.015 14.4 0.1 0.097 11.7 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 PFH38662.1 - 0.016 15.6 1.7 0.14 12.5 0.0 2.8 1 1 0 2 2 2 0 AAA ATPase domain PhoH PF02562.16 PFH38662.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 PFH38662.1 - 0.071 12.7 0.0 0.87 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 PFH38662.1 - 0.097 11.6 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 PFH38662.1 - 0.14 11.9 0.6 0.85 9.4 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MipZ PF09140.11 PFH38662.1 - 0.16 11.2 0.0 0.59 9.4 0.0 1.9 2 0 0 2 2 2 0 ATPase MipZ AAA_18 PF13238.6 PFH38662.1 - 0.2 12.2 0.0 0.64 10.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pkinase PF00069.25 PFH38665.1 - 1.4e-15 57.3 0.0 1.9e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH38665.1 - 3.7e-08 33.0 0.0 4.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH38665.1 - 1e-07 31.6 0.0 1.3e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PFH38665.1 - 0.00051 20.0 0.0 0.00072 19.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PFH38665.1 - 0.19 10.7 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 PFH38666.1 - 1.4e-19 70.5 0.0 7.4e-19 68.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PFH38666.1 - 5e-08 32.5 0.0 2.8e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PFH38666.1 - 2.4e-07 30.4 0.0 5.6e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PFH38666.1 - 0.096 12.0 0.0 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SMC_N PF02463.19 PFH38667.1 - 2.6e-62 210.1 31.5 1.1e-61 208.0 31.5 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PFH38667.1 - 1e-21 77.4 0.0 3.1e-21 75.9 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 PFH38667.1 - 1.7e-14 54.4 2.6 5.4e-07 29.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PFH38667.1 - 1.1e-07 32.0 14.1 1.1e-07 32.0 14.1 4.2 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 PFH38667.1 - 3.2e-06 26.8 0.0 7.2e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF5082 PF16888.5 PFH38667.1 - 0.0027 18.0 8.8 0.0027 18.0 8.8 6.8 4 2 4 8 8 8 1 Domain of unknown function (DUF5082) ABC_tran PF00005.27 PFH38667.1 - 0.008 16.7 0.0 0.008 16.7 0.0 6.0 4 2 0 4 4 4 1 ABC transporter AAA_22 PF13401.6 PFH38667.1 - 2.1 8.6 0.0 2.1 8.6 0.0 4.4 4 1 0 4 4 4 0 AAA domain ThrE PF06738.12 PFH38667.1 - 2.8 7.3 3.8 21 4.3 0.8 3.2 3 0 0 3 3 3 0 Putative threonine/serine exporter Lactamase_B_2 PF12706.7 PFH38669.1 - 2.4e-14 53.3 0.0 5.2e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 PFH38669.1 - 8.5e-07 29.0 0.0 0.00012 22.1 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Ribosomal_S25 PF03297.15 PFH38670.1 - 1.4e-42 144.0 3.7 1.6e-42 143.8 3.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Fe_dep_repress PF01325.19 PFH38670.1 - 0.035 14.3 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 PFH38670.1 - 0.054 13.1 0.1 0.074 12.6 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 PFH38670.1 - 0.091 13.1 0.0 0.18 12.2 0.0 1.5 1 1 0 1 1 1 0 Transcriptional regulator Peptidase_M28 PF04389.17 PFH38671.1 - 9.2e-10 38.5 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PAN_4 PF14295.6 PFH38672.1 - 0.00093 19.1 0.3 0.0016 18.3 0.3 1.4 1 0 0 1 1 1 1 PAN domain Ribosomal_L18p PF00861.22 PFH38673.1 - 0.00096 19.5 0.2 0.00096 19.5 0.2 1.8 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_S11 PF00411.19 PFH38673.1 - 0.0012 19.3 0.8 0.0012 19.3 0.8 1.8 2 0 0 2 2 2 1 Ribosomal protein S11 COPI_assoc PF08507.10 PFH38674.1 - 4.7e-12 46.1 8.4 6.2e-12 45.7 8.4 1.1 1 0 0 1 1 1 1 COPI associated protein HAP PF03866.13 PFH38674.1 - 0.0055 16.7 1.0 0.0055 16.7 1.0 1.9 2 0 0 2 2 2 1 Hydrophobic abundant protein (HAP) Ribosomal_L38e PF01781.18 PFH38677.1 - 5.5e-29 100.1 0.4 6.3e-29 99.9 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Pkinase PF00069.25 PFH38678.1 - 1.7e-35 122.7 0.0 1.2e-24 87.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PFH38678.1 - 4.4e-26 91.7 0.0 2.3e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PFH38678.1 - 0.00018 21.5 0.3 0.00047 20.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PFH38678.1 - 0.0027 17.1 0.0 0.14 11.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Peptidase_S8 PF00082.22 PFH38679.1 - 9.3e-44 149.9 8.2 9.3e-44 149.9 8.2 1.8 2 0 0 2 2 2 1 Subtilase family RNase_PH PF01138.21 PFH38680.1 - 3.4e-16 59.9 0.1 3.5e-15 56.7 0.1 2.2 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PFH38680.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Arv1 PF04161.13 PFH38681.1 - 2.7e-32 112.6 0.0 4.7e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Arv1-like family HscB_4_cys PF18256.1 PFH38684.1 - 0.045 13.6 1.7 0.27 11.1 1.7 2.5 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif LIM PF00412.22 PFH38684.1 - 0.19 12.0 2.0 0.47 10.7 2.0 1.7 1 1 0 1 1 1 0 LIM domain START PF01852.19 PFH38685.1 - 5.5e-22 78.2 0.1 9.5e-22 77.4 0.1 1.3 1 0 0 1 1 1 1 START domain LapA_dom PF06305.11 PFH38685.1 - 0.075 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Myosin_head PF00063.21 PFH38687.1 - 3.3e-165 551.1 0.0 9.3e-82 275.3 0.0 3.8 2 2 0 2 2 2 2 Myosin head (motor domain) IQ PF00612.27 PFH38687.1 - 0.0053 16.4 6.2 0.017 14.8 0.5 3.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif MMS1_N PF10433.9 PFH38689.1 - 2e-154 514.9 0.0 2.7e-154 514.4 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 PFH38689.1 - 3.6e-83 279.6 0.0 1.7e-81 274.0 0.0 2.7 3 0 0 3 3 3 1 CPSF A subunit region DUF1179 PF06678.11 PFH38690.1 - 0.075 13.0 0.0 0.075 13.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1179) Adap_comp_sub PF00928.21 PFH38692.1 - 4.2e-73 246.0 0.0 5.5e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family TPR_6 PF13174.6 PFH38693.1 - 0.11 13.2 0.6 0.3 11.8 0.6 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 PFH38694.1 - 1.4e-11 44.1 0.2 3.7e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PFH38694.1 - 5.1e-10 40.3 0.2 5.1e-10 40.3 0.2 4.0 4 0 0 4 4 4 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PFH38694.1 - 1.8e-09 37.7 0.0 1.1e-07 31.8 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 PFH38694.1 - 0.0011 18.9 1.1 0.0027 17.6 1.1 1.6 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 PFH38694.1 - 0.0011 18.6 0.1 0.0019 17.8 0.1 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Thioesterase PF00975.20 PFH38694.1 - 0.011 15.9 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain FSH1 PF03959.13 PFH38694.1 - 0.011 15.3 0.0 0.039 13.6 0.0 1.8 2 1 0 2 2 2 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 PFH38694.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.12 PFH38694.1 - 0.028 14.4 0.1 3.5 7.5 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 PFH38694.1 - 0.037 13.8 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family EELM2 PF15863.5 PFH38695.1 - 1.6e-68 230.2 0.0 9.4e-62 208.2 0.1 2.4 2 0 0 2 2 2 2 Extended EGL-27 and MTA1 homology domain PHD PF00628.29 PFH38695.1 - 1.7e-08 34.2 8.4 1.7e-08 34.2 8.4 1.7 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 PFH38695.1 - 0.0015 18.8 2.3 0.0032 17.7 2.3 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PFH38695.1 - 0.019 15.2 0.6 0.044 13.9 0.6 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-PHD-like PF15446.6 PFH38695.1 - 0.21 11.2 6.3 0.076 12.6 1.9 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain TMF_TATA_bd PF12325.8 PFH38696.1 - 0.013 15.7 0.6 0.013 15.7 0.6 3.0 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding Sec23_helical PF04815.15 PFH38696.1 - 0.17 11.8 0.2 0.32 10.8 0.2 1.5 1 0 0 1 1 1 0 Sec23/Sec24 helical domain APG5 PF04106.12 PFH38698.1 - 7.4e-28 97.7 0.0 1.2e-26 93.7 0.0 2.6 1 1 0 1 1 1 1 Autophagy protein Apg5 MIP PF00230.20 PFH38700.1 - 9.5 5.9 14.4 0.087 12.5 0.7 3.1 4 0 0 4 4 4 0 Major intrinsic protein AAA_6 PF12774.7 PFH38701.1 - 1e-129 432.3 0.0 5.9e-129 429.7 0.0 2.3 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PFH38701.1 - 3.4e-87 293.1 6.6 1.3e-85 287.9 0.1 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PFH38701.1 - 2.5e-78 263.4 0.0 1.2e-77 261.2 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 PFH38701.1 - 2.6e-68 230.2 0.0 2.8e-37 128.5 0.0 2.9 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_9 PF12781.7 PFH38701.1 - 1.1e-51 175.1 0.0 2.7e-39 134.6 0.0 3.5 3 0 0 3 3 3 2 ATP-binding dynein motor region AAA_7 PF12775.7 PFH38701.1 - 3.9e-47 160.1 0.0 3.6e-42 143.9 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 PFH38701.1 - 6.3e-42 143.8 10.4 1.1e-41 143.0 10.4 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 PFH38701.1 - 1.5e-38 132.2 0.0 3.1e-38 131.2 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PFH38701.1 - 1.4e-36 125.2 0.0 6.7e-36 123.0 0.0 2.3 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 PFH38701.1 - 1.6e-19 70.3 0.0 0.004 17.1 0.0 6.4 5 1 0 5 5 5 5 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 PFH38701.1 - 6.4e-10 39.2 0.0 1.9e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 PFH38701.1 - 8.2e-10 39.1 1.8 0.045 14.0 0.0 6.3 5 1 1 6 6 5 2 AAA domain AAA PF00004.29 PFH38701.1 - 2.2e-08 34.6 0.1 0.17 12.3 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_lid_1 PF17857.1 PFH38701.1 - 3.6e-07 30.3 0.0 2.1e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_18 PF13238.6 PFH38701.1 - 5.5e-06 27.0 0.4 0.035 14.6 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 PFH38701.1 - 6e-05 22.8 4.3 0.2 11.4 0.2 3.9 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 PFH38701.1 - 0.0012 17.9 0.5 0.56 9.2 0.0 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein HrpB7 PF09486.10 PFH38701.1 - 0.003 18.0 10.4 0.003 18.0 10.4 8.8 7 2 2 9 9 7 1 Bacterial type III secretion protein (HrpB7) RNA_helicase PF00910.22 PFH38701.1 - 0.0036 17.7 0.4 4.2 7.8 0.0 3.7 4 0 0 4 4 3 1 RNA helicase FtsK_SpoIIIE PF01580.18 PFH38701.1 - 0.0037 16.6 0.1 2.2 7.6 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.6 PFH38701.1 - 0.0041 16.8 2.0 5 6.9 0.1 4.2 4 0 0 4 4 4 0 P-loop containing region of AAA domain AAA_19 PF13245.6 PFH38701.1 - 0.0044 17.4 4.5 2 8.8 0.1 4.3 4 0 0 4 4 4 1 AAA domain Spc29 PF17082.5 PFH38701.1 - 0.008 16.1 1.0 4.3 7.1 0.0 2.6 2 0 0 2 2 2 1 Spindle Pole Component 29 Sigma54_activat PF00158.26 PFH38701.1 - 0.017 14.8 0.1 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain Rad17 PF03215.15 PFH38701.1 - 0.021 14.7 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_33 PF13671.6 PFH38701.1 - 0.026 14.7 6.5 7.8 6.7 0.0 5.8 6 0 0 6 6 4 0 AAA domain Mg_chelatase PF01078.21 PFH38701.1 - 0.027 13.9 1.0 5.8 6.2 0.0 4.0 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 PFH38701.1 - 0.063 12.8 2.7 1.1 8.8 0.2 3.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 PFH38701.1 - 0.085 13.2 0.0 0.085 13.2 0.0 9.2 12 0 0 12 12 6 0 AAA ATPase domain TsaE PF02367.17 PFH38701.1 - 0.085 12.9 0.8 15 5.6 0.0 3.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AKNA PF12443.8 PFH38701.1 - 0.094 13.4 6.0 0.92 10.2 1.5 3.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor ABC_tran PF00005.27 PFH38701.1 - 0.12 12.9 3.2 9.1 6.8 0.0 4.3 3 0 0 3 3 3 0 ABC transporter DUF1932 PF09130.11 PFH38701.1 - 0.19 11.7 7.0 0.13 12.2 0.8 3.8 3 0 0 3 3 2 0 Domain of unknown function (DUF1932) ATP_bind_1 PF03029.17 PFH38701.1 - 0.6 9.8 2.9 14 5.4 0.1 4.0 5 0 0 5 5 4 0 Conserved hypothetical ATP binding protein Bacillus_HBL PF05791.11 PFH38701.1 - 1.2 8.9 3.5 3.2 7.5 0.1 2.9 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) NACHT PF05729.12 PFH38701.1 - 5.3 6.9 6.5 56 3.6 0.1 4.7 5 0 0 5 5 4 0 NACHT domain FlaC_arch PF05377.11 PFH38701.1 - 9.1 6.8 10.6 7.8 7.0 0.6 4.1 5 0 0 5 5 3 0 Flagella accessory protein C (FlaC) CDC50 PF03381.15 PFH38702.1 - 1.7e-42 145.9 0.0 2.2e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CDC50 PF03381.15 PFH38703.1 - 1.6e-50 172.2 0.0 2.1e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family AAA PF00004.29 PFH38704.1 - 2.4e-59 199.5 0.0 2.1e-41 141.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PFH38704.1 - 9.2e-18 63.8 3.4 9.9e-08 31.7 0.1 3.1 3 0 0 3 3 2 2 AAA+ lid domain IstB_IS21 PF01695.17 PFH38704.1 - 1.6e-09 37.7 0.0 0.00071 19.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.6 PFH38704.1 - 2.2e-09 37.9 5.9 0.00016 22.1 0.0 3.9 4 0 0 4 4 2 2 AAA ATPase domain AAA_18 PF13238.6 PFH38704.1 - 1.5e-08 35.2 0.1 0.00013 22.5 0.1 3.4 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.12 PFH38704.1 - 2.4e-08 33.9 0.0 0.00013 21.8 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PFH38704.1 - 1.9e-07 31.1 0.1 0.00059 19.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PFH38704.1 - 6e-07 29.8 0.0 0.0099 16.2 0.0 3.4 3 1 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 PFH38704.1 - 1.3e-06 28.8 0.0 0.012 16.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.13 PFH38704.1 - 1.4e-06 27.7 0.1 0.026 13.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 PFH38704.1 - 2.2e-06 27.9 0.1 0.0041 17.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 PFH38704.1 - 1.4e-05 25.2 0.0 0.01 15.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 PFH38704.1 - 2.9e-05 24.0 0.0 0.4 10.6 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA_28 PF13521.6 PFH38704.1 - 4.6e-05 23.7 0.9 0.026 14.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 PFH38704.1 - 0.00011 22.8 0.1 0.79 10.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_24 PF13479.6 PFH38704.1 - 0.00038 20.2 0.1 0.26 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 PFH38704.1 - 0.00043 19.7 0.1 0.054 12.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 PFH38704.1 - 0.00093 19.2 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea TsaE PF02367.17 PFH38704.1 - 0.001 19.1 0.0 0.08 12.9 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 PFH38704.1 - 0.0013 18.3 0.2 0.12 11.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PFH38704.1 - 0.002 17.4 0.0 0.02 14.2 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.6 PFH38704.1 - 0.0033 17.3 0.6 4.9 6.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.14 PFH38704.1 - 0.0033 17.6 0.0 0.04 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 PFH38704.1 - 0.004 16.9 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.16 PFH38704.1 - 0.0052 16.3 0.1 2.3 7.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein NB-ARC PF00931.22 PFH38704.1 - 0.0052 16.0 0.0 4.6 6.4 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain Bac_DnaA PF00308.18 PFH38704.1 - 0.006 16.5 0.1 2.1 8.1 0.0 2.5 3 0 0 3 3 2 1 Bacterial dnaA protein AAA_7 PF12775.7 PFH38704.1 - 0.017 14.6 0.0 1.5 8.3 0.0 2.6 3 0 0 3 3 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 PFH38704.1 - 0.026 13.6 0.0 0.21 10.7 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Rad17 PF03215.15 PFH38704.1 - 0.027 14.4 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 PFH38704.1 - 0.032 14.1 0.0 7.2 6.5 0.0 2.5 2 0 0 2 2 2 0 NTPase Viral_helicase1 PF01443.18 PFH38704.1 - 0.041 13.6 0.0 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 PFH38704.1 - 0.11 12.6 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 PFH38704.1 - 0.14 12.0 0.0 0.78 9.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 PFH38704.1 - 0.16 11.9 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 PFH38704.1 - 0.16 12.4 1.0 18 5.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain RINT1_TIP1 PF04437.13 PFH38706.1 - 0.0001 21.4 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family LNS2 PF08235.13 PFH38707.1 - 2e-94 315.3 0.0 2.9e-94 314.8 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 PFH38707.1 - 9.8e-30 102.5 0.0 2e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 PFH38707.1 - 2.3e-19 69.4 0.0 3.9e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain TTL PF03133.15 PFH38709.1 - 9.1e-77 258.1 0.0 1.5e-76 257.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PFH38709.1 - 1.1e-07 31.3 0.0 6.9e-05 22.2 0.0 3.1 3 0 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PFH38709.1 - 2.3e-05 23.8 0.0 0.013 14.8 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 PFH38709.1 - 0.018 14.6 0.0 0.82 9.2 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain DUF2362 PF10154.9 PFH38712.1 - 2.8e-16 59.6 0.0 9.4e-07 28.1 0.0 3.9 4 0 0 4 4 4 3 Uncharacterized conserved protein (DUF2362) CRF PF00473.17 PFH38712.1 - 0.1 12.7 1.2 0.23 11.6 0.1 2.1 2 0 0 2 2 2 0 Corticotropin-releasing factor family FAST_1 PF06743.15 PFH38713.1 - 1.4e-07 31.3 5.8 0.013 15.4 0.0 6.3 5 1 3 8 8 8 4 FAST kinase-like protein, subdomain 1 DUF778 PF05608.12 PFH38714.1 - 3.1e-33 115.7 3.0 2.8e-18 67.0 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF778) Peptidase_C97 PF05903.14 PFH38714.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 PPPDE putative peptidase domain zf-C3HC4_3 PF13920.6 PFH38714.1 - 0.47 10.3 3.6 2.6 8.0 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Glyco_trans_1_4 PF13692.6 PFH38717.1 - 6.4e-06 26.6 0.0 1.4e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 PFH38717.1 - 0.0081 15.7 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PFH38717.1 - 0.23 11.5 1.2 0.52 10.3 0.1 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 E1-E2_ATPase PF00122.20 PFH38717.1 - 3.5 7.1 4.1 1.5 8.3 0.3 2.1 2 0 0 2 2 2 0 E1-E2 ATPase D123 PF07065.14 PFH38718.1 - 1e-37 129.9 0.0 1.7e-22 80.0 0.0 4.3 4 0 0 4 4 4 4 D123 MFS_1 PF07690.16 PFH38719.1 - 8.4e-20 71.0 43.6 2.5e-13 49.7 3.4 3.7 3 1 1 4 4 4 3 Major Facilitator Superfamily OATP PF03137.20 PFH38719.1 - 1.5e-17 63.2 6.0 1.1e-07 30.6 0.0 3.2 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 PFH38719.1 - 3.8e-08 32.6 0.3 3.8e-08 32.6 0.3 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter Pinin_SDK_N PF04697.13 PFH38719.1 - 4.6 7.9 7.9 11 6.6 1.3 3.1 2 0 0 2 2 2 0 pinin/SDK conserved region Guanylate_cyc PF00211.20 PFH38720.1 - 3.5e-17 62.6 0.0 6.5e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPR_2 PF07719.17 PFH38720.1 - 0.13 12.4 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat NdhN PF11909.8 PFH38721.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N PhaC_N PF07167.13 PFH38722.1 - 0.058 13.1 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Pro_isomerase PF00160.21 PFH38723.1 - 5.6e-47 159.9 0.1 6.3e-47 159.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 PFH38723.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain FAM176 PF14851.6 PFH38725.1 - 0.013 15.2 0.4 0.013 15.2 0.4 3.5 4 0 0 4 4 4 0 FAM176 family PBP1_TM PF14812.6 PFH38725.1 - 0.062 13.7 9.4 1.9 8.9 2.9 3.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.13 PFH38725.1 - 4.1 7.2 12.8 1.8 8.4 1.0 3.3 3 0 0 3 3 3 0 Sigma-70, non-essential region PIP5K PF01504.18 PFH38726.1 - 2.5e-81 272.9 0.0 4e-81 272.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_7 PF13499.6 PFH38726.1 - 0.0015 18.9 0.0 0.0059 17.0 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PFH38726.1 - 0.0021 17.5 0.0 0.0058 16.1 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 PFH38726.1 - 0.0049 16.7 0.1 0.017 15.0 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PFH38726.1 - 0.0059 16.5 0.0 0.024 14.5 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 PFH38726.1 - 0.023 14.2 0.0 0.064 12.8 0.0 1.8 1 0 0 1 1 1 0 EF hand NADPH_Ox PF08414.10 PFH38726.1 - 0.039 14.3 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase TMEM192 PF14802.6 PFH38726.1 - 0.22 10.6 0.1 0.35 9.9 0.1 1.2 1 0 0 1 1 1 0 TMEM192 family Spec3 PF15795.5 PFH38727.1 - 0.002 18.6 7.4 0.002 18.6 7.4 2.1 1 1 1 2 2 2 2 Ectodermal ciliogenesis protein EutB PF06751.11 PFH38727.1 - 0.062 12.1 0.0 0.064 12.1 0.0 1.0 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) DUF3040 PF11239.8 PFH38727.1 - 0.22 11.8 4.2 0.63 10.3 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Dpy-30 PF05186.13 PFH38728.1 - 9.2e-14 50.9 0.0 1.5e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 PFH38728.1 - 5.6e-08 33.0 0.0 0.001 19.2 0.0 2.9 2 1 0 3 3 3 2 Adenylate kinase AAA_18 PF13238.6 PFH38728.1 - 9.5e-05 23.0 1.3 0.00075 20.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 PFH38728.1 - 0.0011 19.5 5.5 0.011 16.1 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 PFH38728.1 - 0.0079 16.6 0.0 0.022 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 PFH38728.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 PFH38728.1 - 0.013 15.9 0.0 0.013 15.9 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 PFH38728.1 - 0.026 13.6 0.0 0.048 12.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.12 PFH38728.1 - 0.034 13.9 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PFH38728.1 - 0.036 14.1 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 PFH38728.1 - 0.052 12.8 3.5 0.074 12.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 PFH38728.1 - 0.055 13.0 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PFH38728.1 - 0.055 13.7 0.0 0.26 11.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PFH38728.1 - 0.06 13.5 0.0 0.06 13.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 PFH38728.1 - 0.066 13.5 0.0 0.066 13.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 PFH38728.1 - 0.085 12.1 0.0 0.085 12.1 0.0 1.8 2 0 0 2 2 1 0 Zeta toxin RNA_helicase PF00910.22 PFH38728.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase GMP_synt_C PF00958.22 PFH38729.1 - 1e-40 137.6 0.0 2.1e-40 136.7 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 PFH38729.1 - 3.7e-34 118.2 0.0 6e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 PFH38729.1 - 2.8e-08 33.2 0.0 8e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 PFH38729.1 - 9.1e-07 28.8 0.1 4.4e-06 26.6 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 PFH38729.1 - 0.00095 18.1 0.1 0.0027 16.5 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 PFH38729.1 - 0.0053 16.3 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC YAcAr PF10686.9 PFH38729.1 - 0.055 13.4 0.4 2.1 8.4 0.0 2.9 2 1 0 2 2 2 0 YspA, cpYpsA-related SLOG family Asn_synthase PF00733.21 PFH38729.1 - 0.16 11.6 0.1 0.28 10.8 0.1 1.3 1 0 0 1 1 1 0 Asparagine synthase PAPS_reduct PF01507.19 PFH38729.1 - 0.18 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family zinc_ribbon_6 PF14599.6 PFH38730.1 - 1.8e-19 69.5 0.0 1.8e-19 69.5 0.0 3.7 3 1 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 PFH38730.1 - 2.1e-17 63.3 23.6 2.1e-17 63.3 23.6 4.0 2 1 0 2 2 2 1 CHY zinc finger zf-RING_2 PF13639.6 PFH38730.1 - 9.7e-05 22.6 15.1 9.7e-05 22.6 15.1 5.1 4 1 1 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 PFH38730.1 - 0.00045 20.2 8.0 0.00045 20.2 8.0 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PFH38730.1 - 0.0018 18.1 11.9 0.0018 18.1 11.9 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PFH38730.1 - 0.0018 18.2 13.6 0.0018 18.2 13.6 5.3 2 1 2 4 4 4 1 zinc-RING finger domain Synaptobrevin PF00957.21 PFH38731.1 - 7.1e-28 96.2 0.5 1e-27 95.8 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PFH38731.1 - 1.6e-17 63.3 0.3 4.3e-17 61.9 0.2 1.7 2 0 0 2 2 2 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 PFH38731.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Cnd2 PF05786.14 PFH38731.1 - 0.21 10.2 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Cyclin PF08613.11 PFH38732.1 - 7.9e-12 45.8 0.1 9.5e-11 42.3 0.1 2.5 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 PFH38732.1 - 0.00026 20.7 0.0 0.42 10.4 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain E1-E2_ATPase PF00122.20 PFH38733.1 - 1.8e-56 190.5 4.3 7.1e-55 185.3 0.8 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 PFH38733.1 - 5.6e-49 166.3 1.2 5.6e-49 166.3 1.2 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 PFH38733.1 - 4.5e-21 74.7 0.0 8.8e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PFH38733.1 - 1.7e-20 74.2 3.3 6.6e-18 65.8 0.1 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PFH38733.1 - 1.4e-18 66.3 0.2 4.7e-18 64.6 0.2 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PFH38733.1 - 5.9e-06 26.2 1.8 0.00025 20.9 1.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PFH38733.1 - 9.4e-05 22.9 0.1 0.00031 21.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 PFH38733.1 - 0.086 13.0 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF5092 PF17010.5 PFH38733.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5092) AhpC-TSA PF00578.21 PFH38734.1 - 7.4e-28 97.0 0.0 9.9e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PFH38734.1 - 4.2e-10 39.5 0.0 5.6e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 PFH38734.1 - 1.4e-08 34.5 0.0 2.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SecE PF00584.20 PFH38736.1 - 2.5e-13 49.7 0.1 3.5e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex EF-hand_7 PF13499.6 PFH38737.1 - 0.052 14.0 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 PFH38737.1 - 0.12 12.3 0.1 0.57 10.1 0.0 2.2 3 0 0 3 3 3 0 EF-hand domain pair Fip1 PF05182.13 PFH38739.1 - 4.1e-06 26.2 2.9 7.1e-06 25.4 2.9 1.4 1 0 0 1 1 1 1 Fip1 motif VPS11_C PF12451.8 PFH38740.1 - 5.4e-08 32.9 1.0 2.2e-07 31.0 0.5 2.3 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 PFH38740.1 - 9.8e-05 22.3 3.6 0.00034 20.6 3.6 2.0 1 0 0 1 1 1 1 Zinc-finger Clathrin PF00637.20 PFH38740.1 - 0.00019 21.3 0.1 0.00057 19.8 0.1 1.8 1 0 0 1 1 1 1 Region in Clathrin and VPS IMCp PF12314.8 PFH38741.1 - 9.4e-26 89.9 18.8 9.4e-26 89.9 18.8 3.4 1 1 1 3 3 3 3 Inner membrane complex protein FAP206 PF12018.8 PFH38742.1 - 2.4e-33 115.9 0.0 4.9e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function PIR PF00399.19 PFH38744.1 - 0.047 13.3 3.0 7.4 6.3 0.2 2.8 2 0 0 2 2 2 0 Yeast PIR protein repeat ChAPs PF09295.10 PFH38746.1 - 1.1e-24 87.3 0.0 1.1e-13 50.9 0.0 3.2 3 0 0 3 3 3 3 ChAPs (Chs5p-Arf1p-binding proteins) VPS9 PF02204.18 PFH38747.1 - 4.3e-23 81.5 0.0 8.6e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Sec62 PF03839.16 PFH38748.1 - 3.6e-33 114.9 6.0 5.7e-33 114.3 6.0 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 zf-PARP PF00645.18 PFH38752.1 - 4.6e-21 75.5 0.1 1.5e-20 73.9 0.1 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.12 PFH38752.1 - 1.1e-15 57.1 1.2 2.1e-15 56.2 0.2 1.9 2 0 0 2 2 2 1 PADR1 (NUC008) domain SAP PF02037.27 PFH38752.1 - 0.00027 20.6 0.4 0.0007 19.3 0.1 1.9 2 0 0 2 2 2 1 SAP domain DUF4160 PF13711.6 PFH38752.1 - 0.13 12.7 0.2 37 4.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4160) zinc_ribbon_9 PF14369.6 PFH38752.1 - 0.31 11.4 2.8 0.85 9.9 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon TF_Zn_Ribbon PF08271.12 PFH38752.1 - 0.47 10.0 4.9 0.1 12.1 0.7 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding SRP-alpha_N PF04086.13 PFH38752.1 - 2.9 7.7 17.7 4.2 7.2 17.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MoeA_N PF03453.17 PFH38755.1 - 4.2e-29 101.3 0.1 9.6e-28 96.9 0.1 2.6 1 1 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 PFH38755.1 - 5.4e-26 91.0 0.0 2.9e-11 43.2 0.0 5.5 4 2 0 4 4 4 4 Probable molybdopterin binding domain MoeA_C PF03454.15 PFH38755.1 - 0.0007 19.7 0.0 0.0037 17.4 0.0 2.2 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) IMP2_N PF18590.1 PFH38756.1 - 1.1e-20 74.0 1.4 2.3e-20 72.9 1.4 1.6 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain DNA_ligase_A_M PF01068.21 PFH38757.1 - 3.9e-31 108.3 0.0 1.1e-24 87.3 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 PFH38757.1 - 2.4e-24 86.6 0.0 4.4e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 PFH38757.1 - 1.8e-12 47.7 0.0 4.7e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 PFH38757.1 - 7.8e-05 23.0 0.0 0.00023 21.5 0.0 1.8 1 1 0 1 1 1 1 RNA ligase BRCT_2 PF16589.5 PFH38757.1 - 0.00024 21.4 0.0 1.1 9.7 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 PFH38757.1 - 0.0024 18.2 0.0 0.031 14.7 0.0 2.4 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 PFH38757.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain PP2C PF00481.21 PFH38758.1 - 5.6e-44 150.7 0.0 6.7e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PFH38758.1 - 7.7e-06 25.9 0.4 0.0058 16.6 0.1 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 PFH38758.1 - 5.4e-05 22.9 0.0 0.0003 20.5 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C DUF2207 PF09972.9 PFH38759.1 - 1.3e-05 24.2 2.7 0.0022 16.9 1.7 2.9 1 1 1 2 2 2 2 Predicted membrane protein (DUF2207) CitMHS PF03600.16 PFH38759.1 - 0.0011 18.2 0.8 0.0014 17.9 0.8 1.2 1 0 0 1 1 1 1 Citrate transporter EMC3_TMCO1 PF01956.16 PFH38759.1 - 0.0026 17.5 0.1 0.0094 15.7 0.1 1.9 2 1 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like Sec62 PF03839.16 PFH38759.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Plasmodium_Vir PF05795.11 PFH38759.1 - 0.043 13.3 0.1 0.068 12.6 0.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein VIT1 PF01988.19 PFH38759.1 - 0.043 13.7 0.7 0.097 12.5 0.7 1.6 1 0 0 1 1 1 0 VIT family SMBP PF16785.5 PFH38759.1 - 0.13 12.5 16.6 0.43 10.8 13.6 2.8 2 1 0 2 2 2 0 Small metal-binding protein Tetraspanin PF00335.20 PFH38759.1 - 0.8 9.4 24.0 5.4 6.6 1.3 3.0 2 1 1 3 3 3 0 Tetraspanin family SpoIIIAH PF12685.7 PFH38759.1 - 1.7 8.4 11.7 46 3.8 0.0 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein RNA_pol_Rpc4 PF05132.14 PFH38759.1 - 4.2 7.8 8.3 8.6 6.8 8.3 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3306 PF11748.8 PFH38759.1 - 5.1 8.0 11.8 12 6.7 11.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) RR_TM4-6 PF06459.12 PFH38759.1 - 5.8 6.7 11.9 11 5.8 11.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tetraspanin PF00335.20 PFH38760.1 - 0.0009 19.0 1.7 0.0009 19.0 1.7 2.1 2 0 0 2 2 2 1 Tetraspanin family TssN PF17555.2 PFH38760.1 - 0.11 11.9 3.5 0.18 11.2 3.5 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN MFS_1 PF07690.16 PFH38761.1 - 2.4e-07 30.0 21.4 2.4e-07 30.0 21.4 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily YqhR PF11085.8 PFH38761.1 - 3.9 7.4 8.8 1.2 9.1 4.4 2.3 2 0 0 2 2 2 0 Conserved membrane protein YqhR MFS_1 PF07690.16 PFH38762.1 - 1.3e-09 37.5 5.0 1.3e-09 37.5 5.0 2.7 2 1 1 3 3 3 1 Major Facilitator Superfamily PET117 PF15786.5 PFH38763.1 - 6.1e-10 39.2 0.1 7.7e-10 38.9 0.1 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Cyto_heme_lyase PF01265.17 PFH38765.1 - 2e-45 155.7 2.2 2e-45 155.7 2.2 2.9 2 1 0 2 2 2 1 Cytochrome c/c1 heme lyase Hat1_N PF10394.9 PFH38766.1 - 1.4e-26 93.7 0.0 2.1e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Met_10 PF02475.16 PFH38768.1 - 2.8e-05 24.0 0.0 4.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 PFH38768.1 - 0.001 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PFH38768.1 - 0.0023 18.6 0.1 0.036 14.8 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 PFH38768.1 - 0.032 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Mito_carr PF00153.27 PFH38770.1 - 1.9e-51 171.9 0.7 6.8e-19 67.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Ran_BP1 PF00638.18 PFH38771.1 - 4e-39 133.7 1.0 6.8e-39 132.9 1.0 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 PFH38771.1 - 0.013 15.5 1.8 0.079 12.9 1.5 2.1 1 1 0 1 1 1 0 WH1 domain DUF179 PF02622.15 PFH38772.1 - 2.2e-10 40.7 0.0 4.3e-07 30.0 0.0 2.9 3 0 0 3 3 3 2 Uncharacterized ACR, COG1678 Ribosomal_L20 PF00453.18 PFH38775.1 - 3.9e-26 91.2 0.7 4.6e-26 91.0 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 GDPD_2 PF13653.6 PFH38775.1 - 0.32 11.5 1.9 0.55 10.8 0.1 2.2 2 1 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family WW PF00397.26 PFH38776.1 - 3.3e-09 36.7 4.9 5.8e-09 35.9 4.9 1.4 1 0 0 1 1 1 1 WW domain Yip1 PF04893.17 PFH38776.1 - 4e-06 26.6 15.0 4e-06 26.6 15.0 2.2 1 1 1 2 2 2 1 Yip1 domain Cyclin PF08613.11 PFH38777.1 - 4.7e-23 82.3 0.0 1.1e-22 81.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin HATPase_c PF02518.26 PFH38778.1 - 1.6e-06 28.6 0.0 5.3e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PFH38778.1 - 0.014 15.2 0.0 0.051 13.4 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Abhydro_lipase PF04083.16 PFH38782.1 - 1.3e-09 37.4 0.0 5.8e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 Partial alpha/beta-hydrolase lipase region BAAT_C PF08840.11 PFH38782.1 - 0.0043 17.0 0.0 0.033 14.1 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 PFH38782.1 - 0.0061 16.2 0.1 0.23 11.0 0.1 2.9 3 0 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PFH38782.1 - 0.0097 15.2 0.1 5.6 6.2 0.2 3.0 3 0 0 3 3 3 2 Serine aminopeptidase, S33 DUF2465 PF10239.9 PFH38783.1 - 1.3e-18 67.4 0.0 2.2e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) DHHC PF01529.20 PFH38784.1 - 4.7e-30 104.4 19.6 7.9e-30 103.7 19.6 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Exo_endo_phos PF03372.23 PFH38786.1 - 0.00018 21.1 0.0 0.00053 19.6 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Isochorismatase PF00857.20 PFH38787.1 - 1.6e-08 34.9 0.0 2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family DUF5455 PF17537.2 PFH38787.1 - 0.091 13.2 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5455) ELFV_dehydrog PF00208.21 PFH38788.1 - 4.4e-85 285.3 3.1 5.6e-85 284.9 3.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 PFH38788.1 - 1.1e-49 167.6 0.0 2.3e-49 166.6 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SPRY PF00622.28 PFH38790.1 - 3.7e-17 62.5 0.0 6.1e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 PFH38790.1 - 5e-09 36.2 0.0 1.3e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain HEAT_EZ PF13513.6 PFH38790.1 - 0.27 11.8 2.2 12 6.5 0.1 3.5 2 1 1 3 3 3 0 HEAT-like repeat Sybindin PF04099.12 PFH38791.1 - 3.9e-44 150.0 0.0 4.4e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 PFH38791.1 - 1.4e-07 31.7 0.0 1.4e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region ABC2_membrane_3 PF12698.7 PFH38792.1 - 4.1 6.4 4.5 5.7 5.9 4.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein PDEase_I PF00233.19 PFH38794.1 - 3.3e-64 216.9 1.2 7.9e-64 215.6 1.2 1.6 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 PFH38794.1 - 0.0064 17.1 0.1 0.053 14.2 0.0 2.5 2 0 0 2 2 2 1 GAF domain DUF4140 PF13600.6 PFH38798.1 - 2.5 8.6 5.9 13 6.3 3.4 3.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) NUDIX PF00293.28 PFH38799.1 - 0.056 13.5 2.0 0.16 12.0 2.0 1.8 1 0 0 1 1 1 0 NUDIX domain ATG16 PF08614.11 PFH38799.1 - 9.9 6.3 134.0 0.048 13.9 30.0 6.8 2 2 3 6 6 6 0 Autophagy protein 16 (ATG16) HSP90 PF00183.18 PFH38800.1 - 7.8e-105 351.7 0.1 3e-101 339.9 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 PFH38800.1 - 2.3e-09 37.2 0.1 5.2e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PFH38800.1 - 2.6e-06 27.9 0.0 5.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GED PF02212.18 PFH38800.1 - 0.3 11.3 1.0 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 Dynamin GTPase effector domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Besnoitia_besnoiti-Bbes1.0/GCA_002563875.1_Bbes1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Besnoitia_besnoiti-Bbes1.0/GCA_002563875.1_Bbes1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Besnoitia_besnoiti-Bbes1.0/GCA_002563875.1_Bbes1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Besnoitia_besnoiti-Bbes1.0/GCA_002563875.1_Bbes1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 00:59:33 2019 # [ok]