# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Atracotoxin PF05353.6 AFZ78905.1 - 0.031 14.1 1.4 0.1 12.4 1.0 1.8 1 0 0 1 1 1 0 Delta Atracotoxin DUF2583 PF10762.4 AFZ78905.1 - 3.1 8.0 6.1 8 6.6 1.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2583) Cyt-b5 PF00173.23 AFZ78907.1 - 2.4e-18 65.6 0.0 3.5e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC_tran PF00005.22 AFZ78908.1 - 3.1e-28 98.8 0.0 2.8e-14 53.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 AFZ78908.1 - 2.7e-05 24.2 0.1 0.055 13.4 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AFZ78908.1 - 9.6e-05 21.8 1.1 0.18 11.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 AFZ78908.1 - 0.00014 22.6 0.3 0.21 12.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.1 AFZ78908.1 - 0.0002 21.7 3.8 0.057 13.7 0.5 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 AFZ78908.1 - 0.00025 20.5 0.0 0.031 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 AFZ78908.1 - 0.00075 19.5 0.2 0.02 14.8 0.1 5.0 7 0 0 7 7 5 2 AAA domain T2SE PF00437.15 AFZ78908.1 - 0.0013 17.7 0.7 0.87 8.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_30 PF13604.1 AFZ78908.1 - 0.0014 18.2 0.1 0.32 10.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 AFZ78908.1 - 0.0019 17.0 0.6 0.0045 15.7 0.0 1.7 2 0 0 2 2 2 1 ArgK protein AAA_18 PF13238.1 AFZ78908.1 - 0.0022 18.3 0.1 1.9 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 AFZ78908.1 - 0.0027 17.5 3.7 0.073 12.8 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function DUF87 UPF0079 PF02367.12 AFZ78908.1 - 0.0041 16.7 0.8 0.16 11.6 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 AFZ78908.1 - 0.0045 16.1 0.2 2.5 7.1 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin DUF258 PF03193.11 AFZ78908.1 - 0.0052 15.9 0.4 0.58 9.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 AFZ78908.1 - 0.0067 16.1 0.5 0.81 9.3 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 AFZ78908.1 - 0.0073 15.7 0.3 0.74 9.2 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 AFZ78908.1 - 0.0079 16.6 0.1 3.3 8.2 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 AFZ78908.1 - 0.0085 15.7 0.5 2.2 7.8 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.1 AFZ78908.1 - 0.01 14.9 0.7 6.5 5.6 0.1 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 AFZ78908.1 - 0.014 15.5 0.0 7.2 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 AFZ78908.1 - 0.014 14.6 0.8 0.15 11.2 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 AFZ78908.1 - 0.036 13.8 1.2 3.9 7.2 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 AFZ78908.1 - 0.055 12.9 1.9 11 5.4 0.2 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 AFZ78908.1 - 0.055 13.3 0.0 6.8 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 AFZ78908.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 AFZ78908.1 - 0.063 13.2 1.1 0.34 10.8 0.0 2.6 3 0 0 3 3 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 AFZ78908.1 - 0.082 12.7 2.5 3.5 7.4 0.0 2.7 3 0 0 3 3 2 0 Dynamin family FAINT PF04385.10 AFZ78909.1 - 2.8e-05 23.8 0.3 0.00023 20.9 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function, DUF529 PfkB PF00294.19 AFZ78910.1 - 1.6e-28 99.6 0.0 2.1e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Metallophos PF00149.23 AFZ78911.1 - 3.5e-41 140.8 0.4 4.3e-41 140.5 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AFZ78911.1 - 0.0058 16.4 0.0 0.0081 16.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SLBP_RNA_bind PF15247.1 AFZ78912.1 - 4.6e-21 74.3 1.0 1.3e-20 72.9 0.4 1.9 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain tRNA-synt_2b PF00587.20 AFZ78913.1 - 4.3e-21 75.2 0.3 7.2e-21 74.5 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AFZ78913.1 - 3.4e-05 23.7 0.0 0.00014 21.7 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 AFZ78913.1 - 0.0053 15.5 0.6 0.0081 14.9 0.4 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Hist_deacetyl PF00850.14 AFZ78914.1 - 6e-76 255.6 0.7 7.4e-76 255.3 0.1 1.3 2 0 0 2 2 2 1 Histone deacetylase domain Yippee-Mis18 PF03226.9 AFZ78915.1 - 1.6e-17 63.3 0.2 1.8e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 AFZ78915.1 - 0.026 14.5 0.7 0.085 12.8 0.1 2.0 2 0 0 2 2 2 0 HNH endonuclease zf-Mss51 PF13824.1 AFZ78915.1 - 0.031 14.1 0.3 4.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2321 PF10083.4 AFZ78915.1 - 0.11 11.9 0.4 0.17 11.3 0.3 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DNA_RNApol_7kD PF03604.8 AFZ78915.1 - 0.14 11.6 1.1 12 5.4 0.0 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 AFZ78915.1 - 0.21 11.4 1.5 1.8 8.4 1.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 AFZ78915.1 - 0.4 10.6 2.5 22 5.1 0.0 3.1 2 1 1 3 3 3 0 Zinc ribbon domain Thioredoxin PF00085.15 AFZ78916.1 - 2.7e-22 78.4 0.8 3.4e-22 78.0 0.6 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AFZ78916.1 - 7.5e-06 25.9 0.3 1.4e-05 25.1 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.19 AFZ78916.1 - 0.00011 22.1 0.3 0.00021 21.1 0.2 1.6 1 1 0 1 1 1 1 Glutaredoxin DUF953 PF06110.6 AFZ78916.1 - 0.0011 18.3 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Redoxin PF08534.5 AFZ78916.1 - 0.0013 18.3 0.1 0.0016 17.9 0.1 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_3 PF13192.1 AFZ78916.1 - 0.0023 17.7 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.1 AFZ78916.1 - 0.011 15.2 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.1 AFZ78916.1 - 0.014 15.5 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.16 AFZ78916.1 - 0.025 14.2 0.1 0.034 13.8 0.1 1.2 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.1 AFZ78916.1 - 0.081 12.9 0.2 0.15 12.1 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 AFZ78916.1 - 0.087 12.3 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin V-ATPase_C PF03223.10 AFZ78917.1 - 6.6e-77 258.9 2.8 7.6e-77 258.7 2.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit C DUF1039 PF06287.6 AFZ78917.1 - 0.012 15.5 0.3 0.085 12.7 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1039) MMR_HSR1 PF01926.18 AFZ78920.1 - 6.9e-14 51.7 0.0 1.6e-13 50.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AFZ78920.1 - 4.1e-09 35.9 0.0 1.7e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 AFZ78920.1 - 0.00067 18.9 0.0 0.032 13.4 0.0 2.5 3 0 0 3 3 3 1 ADP-ribosylation factor family AAA_17 PF13207.1 AFZ78920.1 - 0.00071 20.3 0.0 0.0016 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 AFZ78920.1 - 0.00079 19.2 0.1 0.0054 16.5 0.0 2.1 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.11 AFZ78920.1 - 0.005 15.9 0.0 0.011 14.8 0.0 1.5 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 AFZ78920.1 - 0.0051 16.0 0.0 0.017 14.3 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 AFZ78920.1 - 0.0092 15.3 0.0 0.39 10.0 0.0 2.2 2 0 0 2 2 2 1 Ras family AAA_18 PF13238.1 AFZ78920.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sep15_SelM PF08806.6 AFZ78920.1 - 0.04 13.6 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Sep15/SelM redox domain MobB PF03205.9 AFZ78920.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 AFZ78920.1 - 0.098 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 AFZ78920.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein ATP_bind_1 PF03029.12 AFZ78920.1 - 0.12 11.9 0.1 4.6 6.7 0.0 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 AFZ78920.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain HECT PF00632.20 AFZ78922.1 - 7.7e-97 324.2 0.4 1.5e-96 323.3 0.3 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PH_11 PF15413.1 AFZ78923.1 - 0.12 12.5 9.0 0.4 10.9 0.4 4.1 4 0 0 4 4 4 0 Pleckstrin homology domain LRR_6 PF13516.1 AFZ78923.1 - 0.17 12.0 17.1 19 5.6 0.1 7.4 7 0 0 7 7 7 0 Leucine Rich repeat tRNA_anti-codon PF01336.20 AFZ78924.1 - 0.0073 16.1 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4539 PF15072.1 AFZ78924.1 - 0.084 12.5 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) SNF5 PF04855.7 AFZ78925.1 - 2.5e-06 27.1 5.9 0.0035 16.8 0.1 2.4 2 0 0 2 2 2 2 SNF5 / SMARCB1 / INI1 Telomere_reg-2 PF10193.4 AFZ78925.1 - 0.018 15.2 1.4 0.035 14.3 0.0 2.2 2 0 0 2 2 2 0 Telomere length regulation protein Choline_kinase PF01633.15 AFZ78926.1 - 4.1e-28 98.3 0.0 6.7e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 AFZ78926.1 - 5.3e-10 39.4 0.0 7.9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AFZ78927.1 - 3.7e-24 85.4 0.0 6.5e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 AFZ78927.1 - 1.4e-08 34.7 0.0 2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 AFZ78927.1 - 0.0032 16.6 0.1 0.0057 15.8 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase FAINT PF04385.10 AFZ78928.1 - 2.1e-12 46.7 1.1 5.2e-06 26.2 0.1 3.4 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Hydrolase_3 PF08282.7 AFZ78929.1 - 3.9e-36 124.9 0.0 4.9e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AFZ78929.1 - 0.00015 21.1 0.0 0.022 14.0 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 AFZ78929.1 - 0.049 13.7 0.0 0.096 12.8 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pribosyltran PF00156.22 AFZ78930.1 - 1.2e-11 44.4 0.0 2.8e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Phage_XkdX PF09693.5 AFZ78930.1 - 0.14 11.7 2.2 3.9 7.0 0.0 3.5 4 0 0 4 4 4 0 Phage uncharacterised protein (Phage_XkdX) PfkB PF00294.19 AFZ78931.1 - 1.6e-28 99.6 0.0 2.1e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Pribosyltran PF00156.22 AFZ78932.1 - 5.1e-18 64.9 0.1 6.8e-18 64.5 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Carboxyl_trans PF01039.17 AFZ78932.1 - 0.039 12.2 0.0 0.93 7.7 0.0 2.0 2 0 0 2 2 2 0 Carboxyl transferase domain UPRTase PF14681.1 AFZ78932.1 - 0.052 12.7 0.1 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase Aconitase_2_N PF06434.8 AFZ78932.1 - 0.084 12.2 0.0 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 Aconitate hydratase 2 N-terminus Histone PF00125.19 AFZ78933.1 - 3e-16 59.3 0.1 5.5e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AFZ78933.1 - 0.059 13.4 0.5 0.15 12.1 0.3 1.7 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 AFZ78933.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 AFZ78933.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore component CENP-S COX5B PF01215.14 AFZ78934.1 - 1.2e-12 47.6 0.0 2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Aminotran_1_2 PF00155.16 AFZ78935.1 - 3.3e-56 190.8 0.0 3.7e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II UPF0058 PF01893.11 AFZ78935.1 - 0.045 13.7 0.4 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0058 Ribosomal_TL5_C PF14693.1 AFZ78936.1 - 0.0065 16.6 0.0 0.015 15.4 0.0 1.6 1 1 1 2 2 2 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.14 AFZ78936.1 - 0.023 14.7 0.0 0.17 12.0 0.0 2.3 2 1 0 2 2 2 0 Ribosomal L25p family Pro_isomerase PF00160.16 AFZ78937.1 - 2.8e-41 141.3 1.3 3.5e-41 140.9 0.9 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NTF2 PF02136.15 AFZ78938.1 - 2.3e-25 89.2 0.0 2.6e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 AFZ78938.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) PIP5K PF01504.13 AFZ78940.1 - 1.6e-52 178.1 1.1 4.3e-52 176.7 0.8 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 AFZ78940.1 - 1.1e-10 40.7 0.2 2.9e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Actin PF00022.14 AFZ78941.1 - 8.3e-113 376.7 0.0 1.2e-112 376.2 0.0 1.2 1 0 0 1 1 1 1 Actin DS PF01916.12 AFZ78942.1 - 5e-123 409.9 0.0 5.9e-123 409.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase AAA PF00004.24 AFZ78943.1 - 5.2e-81 269.3 0.2 6.4e-47 159.0 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AFZ78943.1 - 3e-11 43.5 1.4 3.6e-06 27.1 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.9 AFZ78943.1 - 3.1e-11 43.1 0.1 2.8e-05 23.8 0.0 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AFZ78943.1 - 4.9e-09 36.1 0.2 0.0014 18.4 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 AFZ78943.1 - 8.2e-09 35.7 0.1 0.028 14.3 0.0 3.9 2 2 1 4 4 4 2 AAA ATPase domain AAA_2 PF07724.9 AFZ78943.1 - 5e-08 33.0 0.0 0.0023 17.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 AFZ78943.1 - 5.6e-08 32.1 0.0 0.00071 18.6 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 AFZ78943.1 - 1.4e-07 31.6 0.1 0.21 11.7 0.0 3.7 3 0 0 3 3 3 2 RNA helicase TIP49 PF06068.8 AFZ78943.1 - 2.6e-07 29.7 0.0 0.013 14.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 AFZ78943.1 - 5.7e-06 27.1 0.1 0.014 16.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 AFZ78943.1 - 8.7e-06 25.0 0.2 0.037 13.1 0.0 2.6 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 AFZ78943.1 - 9.2e-06 25.1 0.0 0.053 12.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein KaiC PF06745.8 AFZ78943.1 - 1.6e-05 24.1 1.3 3.1 6.8 0.1 4.1 4 0 0 4 4 4 2 KaiC Zeta_toxin PF06414.7 AFZ78943.1 - 4.5e-05 22.6 0.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 AFZ78943.1 - 5.3e-05 23.5 0.1 0.001 19.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 AFZ78943.1 - 0.00017 21.0 0.6 0.82 9.0 0.0 3.9 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.1 AFZ78943.1 - 0.0003 20.7 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AFZ78943.1 - 0.00044 19.9 0.0 0.21 11.3 0.0 2.8 3 0 0 3 3 2 1 Part of AAA domain Bac_DnaA PF00308.13 AFZ78943.1 - 0.0005 19.7 0.0 0.0034 17.0 0.0 2.1 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_24 PF13479.1 AFZ78943.1 - 0.00057 19.5 0.1 0.057 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 AFZ78943.1 - 0.00071 19.8 0.1 0.18 12.1 0.1 3.1 2 1 0 2 2 2 1 ABC transporter NB-ARC PF00931.17 AFZ78943.1 - 0.0016 17.3 0.0 0.076 11.8 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain Arch_ATPase PF01637.13 AFZ78943.1 - 0.0023 17.6 5.1 2.5 7.7 0.4 4.7 3 2 1 4 4 4 1 Archaeal ATPase NACHT PF05729.7 AFZ78943.1 - 0.0029 17.2 0.0 0.059 13.0 0.0 2.6 3 0 0 3 3 2 1 NACHT domain Sigma54_activ_2 PF14532.1 AFZ78943.1 - 0.02 14.9 0.0 7.2 6.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 AFZ78943.1 - 0.021 13.8 0.5 0.13 11.2 0.1 2.5 2 1 0 2 2 2 0 KAP family P-loop domain Sigma54_activat PF00158.21 AFZ78943.1 - 0.03 13.7 0.0 6 6.3 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 AFZ78943.1 - 0.032 14.1 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 AFZ78943.1 - 0.071 12.7 0.0 3.5 7.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NMT PF01233.14 AFZ78944.1 - 7.3e-75 250.0 0.1 1.1e-74 249.4 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 AFZ78944.1 - 1e-51 175.0 0.5 1.9e-51 174.1 0.4 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 AFZ78944.1 - 0.00014 21.7 0.0 0.00035 20.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AFZ78944.1 - 0.0067 16.5 0.0 0.018 15.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CS PF04969.11 AFZ78945.1 - 3.6e-07 30.6 0.1 8.6e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 CS domain DUF1087 PF06465.8 AFZ78945.1 - 0.18 11.7 1.8 0.6 10.0 1.3 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) Pyrophosphatase PF00719.14 AFZ78946.1 - 1.9e-46 157.3 0.0 2.3e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase G-patch_2 PF12656.2 AFZ78947.1 - 0.0065 16.2 0.0 0.026 14.3 0.0 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site Nuf2 PF03800.9 AFZ78948.1 - 1.6e-21 76.7 0.0 4.9e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 Nuf2 family Ribosomal_L9_C PF03948.9 AFZ78948.1 - 0.017 15.1 0.0 0.062 13.3 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain HpcH_HpaI PF03328.9 AFZ78948.1 - 0.13 11.0 0.0 1.8 7.3 0.0 2.1 1 1 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family TPR_MLP1_2 PF07926.7 AFZ78948.1 - 0.23 11.1 21.3 0.031 14.0 2.0 3.0 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 AFZ78948.1 - 0.24 10.4 25.4 0.38 9.7 5.5 2.3 1 1 0 2 2 2 0 Autophagy protein Apg6 ING PF12998.2 AFZ78948.1 - 5.6 7.2 18.2 0.06 13.6 1.3 3.6 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Laminin_II PF06009.7 AFZ78948.1 - 9.4 5.9 19.1 1.2 8.8 2.4 3.6 2 1 2 4 4 4 0 Laminin Domain II Ribosomal_S8 PF00410.14 AFZ78949.1 - 5.8e-24 84.3 0.0 7.3e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 TB2_DP1_HVA22 PF03134.14 AFZ78950.1 - 1.6e-22 79.0 8.5 1.7e-21 75.7 5.9 2.2 1 1 0 1 1 1 1 TB2/DP1, HVA22 family Tic20 PF09685.5 AFZ78950.1 - 0.063 13.2 10.7 0.038 13.9 3.3 2.1 2 0 0 2 2 2 0 Tic20-like protein DUF788 PF05620.6 AFZ78950.1 - 1.4 8.7 4.6 2.1 8.1 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF3487 PF11990.3 AFZ78950.1 - 2.4 7.5 5.0 1.9 7.8 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3487) RRM_1 PF00076.17 AFZ78951.1 - 9.7e-14 50.7 0.0 1.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ78951.1 - 3.3e-06 26.9 0.1 7.2e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AFZ78951.1 - 0.00011 22.0 0.1 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.1 AFZ78951.1 - 0.0051 16.6 0.0 0.023 14.5 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF743 PF05332.6 AFZ78951.1 - 0.012 15.5 1.0 0.035 14.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF743) FYVE PF01363.16 AFZ78952.1 - 1.2e-05 25.0 11.6 1.2e-05 25.0 8.1 2.0 2 0 0 2 2 2 1 FYVE zinc finger TMF_TATA_bd PF12325.3 AFZ78952.1 - 0.00056 19.6 5.6 0.00056 19.6 3.9 2.4 2 1 1 3 3 2 1 TATA element modulatory factor 1 TATA binding GAS PF13851.1 AFZ78952.1 - 0.00095 18.4 9.2 0.00095 18.4 6.4 1.9 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding IncA PF04156.9 AFZ78952.1 - 0.0014 18.2 12.1 0.0029 17.2 6.7 2.1 2 0 0 2 2 2 1 IncA protein DUF4200 PF13863.1 AFZ78952.1 - 0.0058 16.5 5.9 0.0058 16.5 4.1 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4200) DUF1843 PF08898.5 AFZ78952.1 - 0.033 14.2 1.2 0.084 12.9 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) Helitron_like_N PF14214.1 AFZ78952.1 - 0.038 13.7 1.7 0.07 12.8 1.2 1.3 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus YejG PF13989.1 AFZ78952.1 - 0.039 14.0 0.9 0.11 12.5 0.6 1.7 1 0 0 1 1 1 0 YejG-like protein DivIVA PF05103.8 AFZ78952.1 - 0.043 13.8 11.1 0.94 9.5 3.3 3.0 2 1 1 3 3 3 0 DivIVA protein DUF3450 PF11932.3 AFZ78952.1 - 0.045 12.9 8.8 0.71 9.0 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) THOC7 PF05615.8 AFZ78952.1 - 0.049 13.8 10.0 0.73 10.0 3.1 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 DUF869 PF05911.6 AFZ78952.1 - 0.059 11.6 12.9 0.1 10.8 9.0 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) TPR_MLP1_2 PF07926.7 AFZ78952.1 - 0.11 12.2 11.2 0.02 14.6 5.3 1.5 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein Mnd1 PF03962.10 AFZ78952.1 - 0.19 11.3 7.7 0.36 10.4 5.4 1.4 1 0 0 1 1 1 0 Mnd1 family DUF2353 PF09789.4 AFZ78952.1 - 0.27 10.4 13.2 0.45 9.7 8.9 1.5 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) SNAPc19 PF15497.1 AFZ78952.1 - 0.29 11.3 11.1 0.33 11.1 4.7 2.3 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 GrpE PF01025.14 AFZ78952.1 - 0.45 10.0 12.6 0.12 11.9 0.9 2.8 2 1 1 3 3 3 0 GrpE NPV_P10 PF05531.7 AFZ78952.1 - 0.54 10.5 4.3 0.5 10.6 0.6 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 AFZ78952.1 - 0.58 7.9 3.5 0.65 7.7 2.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-Q PF13094.1 AFZ78952.1 - 0.75 9.8 11.6 0.18 11.8 5.5 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Tox-ODYAM1 PF15642.1 AFZ78952.1 - 0.87 8.1 6.3 1.1 7.8 4.4 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Cauli_AT PF03233.8 AFZ78952.1 - 0.89 9.2 8.5 0.079 12.6 2.4 1.8 2 1 0 2 2 1 0 Aphid transmission protein WEMBL PF05701.6 AFZ78952.1 - 1.1 7.6 12.7 3.7 5.8 7.3 1.8 1 1 0 1 1 1 0 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 AFZ78952.1 - 1.5 8.6 18.5 0.37 10.6 9.8 2.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FadA PF09403.5 AFZ78952.1 - 1.6 8.7 8.3 0.23 11.4 2.9 1.7 2 0 0 2 2 2 0 Adhesion protein FadA COG2 PF06148.6 AFZ78952.1 - 1.7 8.5 11.9 0.5 10.2 4.7 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Uso1_p115_C PF04871.8 AFZ78952.1 - 2 8.3 8.8 0.32 10.9 3.6 1.5 2 0 0 2 2 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region FliJ PF02050.11 AFZ78952.1 - 2.1 8.3 15.5 1.2 9.2 8.9 1.9 2 1 0 2 2 1 0 Flagellar FliJ protein SlyX PF04102.7 AFZ78952.1 - 2.2 8.7 7.8 5.8 7.3 0.2 3.1 1 1 0 2 2 2 0 SlyX ATG16 PF08614.6 AFZ78952.1 - 2.7 7.7 17.0 0.35 10.6 8.5 1.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin PF02996.12 AFZ78952.1 - 4.4 6.9 8.9 2.9 7.5 0.8 3.1 1 1 2 3 3 3 0 Prefoldin subunit Med9 PF07544.8 AFZ78952.1 - 6 6.6 11.1 0.99 9.1 0.3 2.6 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 zf-B_box PF00643.19 AFZ78952.1 - 7.2 6.5 15.2 55 3.7 0.1 3.0 2 1 0 2 2 2 0 B-box zinc finger IncA PF04156.9 AFZ78954.1 - 0.0018 17.9 46.8 0.0037 16.8 13.9 3.1 1 1 2 3 3 3 2 IncA protein DUF1192 PF06698.6 AFZ78954.1 - 0.2 11.4 3.7 0.42 10.4 0.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) H-K_ATPase_N PF09040.6 AFZ78954.1 - 0.22 11.6 0.3 0.45 10.6 0.2 1.4 1 0 0 1 1 1 0 Gastric H+/K+-ATPase, N terminal domain Reo_sigmaC PF04582.7 AFZ78954.1 - 0.27 10.3 10.9 2.1 7.4 1.0 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Lipoprotein_7 PF01540.11 AFZ78954.1 - 0.48 9.4 34.6 0.56 9.2 18.8 2.3 1 1 1 2 2 2 0 Adhesin lipoprotein DUF3584 PF12128.3 AFZ78954.1 - 0.68 7.1 42.7 1 6.6 29.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 AFZ78954.1 - 2.5 7.9 56.2 0.012 15.4 8.2 3.2 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1515 PF07439.6 AFZ78954.1 - 6.6 6.5 18.4 1.5 8.6 0.7 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) DUF2120 PF09893.4 AFZ78955.1 - 0.55 10.1 4.2 0.85 9.5 1.9 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) UPF0020 PF01170.13 AFZ78956.1 - 0.001 18.7 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 PV_NSP1 PF12433.3 AFZ78956.1 - 0.037 14.0 0.1 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Parvovirus non-structural protein 1 DXP_reductoisom PF02670.11 AFZ78957.1 - 5.9e-36 123.8 0.4 1.1e-35 122.9 0.3 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.1 AFZ78957.1 - 1.6e-35 121.7 0.0 3e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.7 AFZ78957.1 - 2.8e-31 107.2 0.5 2.5e-30 104.1 0.3 2.3 1 1 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal Semialdhyde_dh PF01118.19 AFZ78957.1 - 0.039 14.2 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_tran_28_C PF04101.11 AFZ78957.1 - 0.095 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Pep3_Vps18 PF05131.9 AFZ78959.1 - 1.2e-21 76.6 0.0 5.5e-21 74.5 0.0 2.0 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.4 AFZ78959.1 - 2.7e-06 27.5 0.6 7e-06 26.1 0.1 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 RasGAP PF00616.14 AFZ78959.1 - 0.00092 18.9 0.2 0.0024 17.5 0.2 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase zf-RING_2 PF13639.1 AFZ78959.1 - 0.0014 18.3 0.9 0.0014 18.3 0.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 AFZ78959.1 - 0.028 14.0 0.5 0.13 11.9 0.4 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 AFZ78959.1 - 0.083 12.6 0.9 0.19 11.4 0.2 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 AFZ78959.1 - 0.41 10.7 5.8 0.11 12.5 0.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AFZ78959.1 - 4.4 7.1 7.5 2.1 8.1 1.8 2.8 2 1 1 3 3 3 0 zinc-RING finger domain Myb_DNA-bind_6 PF13921.1 AFZ78960.1 - 0.0028 17.7 0.7 0.0068 16.4 0.5 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-SNAP50_C PF12251.3 AFZ78961.1 - 2.1e-48 164.2 4.5 3.6e-48 163.5 3.1 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF2197 PF09963.4 AFZ78961.1 - 0.016 15.1 1.5 0.016 15.1 1.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) Ribosomal_L27e PF01777.13 AFZ78962.1 - 9.9e-29 99.3 6.8 1.3e-28 98.9 4.7 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 AFZ78962.1 - 0.0058 16.3 0.1 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 KOW motif ENTH PF01417.15 AFZ78963.1 - 5.2e-05 23.1 3.5 0.0034 17.2 0.2 2.6 2 1 0 2 2 2 2 ENTH domain Ribosomal_L29e PF01779.12 AFZ78965.1 - 2e-21 75.5 12.5 2e-21 75.5 8.7 1.4 2 0 0 2 2 2 1 Ribosomal L29e protein family ECR1_N PF14382.1 AFZ78966.1 - 1.1e-08 34.2 0.0 2.3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Ribosomal_L18p PF00861.17 AFZ78967.1 - 1.8e-37 128.1 0.1 1.8e-37 128.1 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 AFZ78967.1 - 7.7e-32 109.7 6.2 1.7e-31 108.6 4.3 1.6 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region DUF1476 PF07345.6 AFZ78967.1 - 0.07 13.3 0.0 0.24 11.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1476) Ribosomal_L7Ae PF01248.21 AFZ78968.1 - 1.7e-21 75.4 0.3 3.8e-21 74.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Las1 PF04031.8 AFZ78970.1 - 3e-36 124.4 0.4 5.3e-36 123.6 0.3 1.4 1 0 0 1 1 1 1 Las1-like zf-CCCH PF00642.19 AFZ78971.1 - 8.5e-09 34.8 8.3 2.2e-06 27.1 0.4 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 AFZ78971.1 - 0.13 11.7 1.1 0.27 10.7 0.7 1.5 1 0 0 1 1 1 0 Putative zinc-finger domain PrmA PF06325.8 AFZ78972.1 - 1.3e-11 44.2 0.0 2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 AFZ78972.1 - 2.2e-11 43.5 0.3 4.3e-11 42.6 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AFZ78972.1 - 1.7e-10 41.4 0.0 3.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AFZ78972.1 - 1.2e-08 35.3 0.0 4e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AFZ78972.1 - 9.1e-08 31.6 0.3 1.5e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 AFZ78972.1 - 2.1e-07 31.2 0.0 9.6e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 AFZ78972.1 - 4.7e-07 29.0 0.2 6.5e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 AFZ78972.1 - 2.8e-06 27.3 0.0 5.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AFZ78972.1 - 1.3e-05 24.9 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AFZ78972.1 - 3.1e-05 24.3 0.0 6.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 AFZ78972.1 - 5.9e-05 21.9 0.0 8.1e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.14 AFZ78972.1 - 5.9e-05 23.1 0.0 9.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.9 AFZ78972.1 - 0.00044 19.4 0.3 0.00099 18.3 0.2 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 AFZ78972.1 - 0.0011 18.4 1.0 0.0015 18.0 0.1 1.6 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 AFZ78972.1 - 0.005 15.9 0.1 0.0073 15.4 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 AFZ78972.1 - 0.01 15.4 0.2 0.017 14.7 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 AFZ78972.1 - 0.038 13.6 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 AFZ78972.1 - 0.088 12.1 0.1 0.28 10.5 0.0 1.9 3 0 0 3 3 3 0 Conserved hypothetical protein 95 Rad52_Rad22 PF04098.10 AFZ78972.1 - 0.089 12.5 0.1 0.35 10.5 0.0 1.9 2 0 0 2 2 2 0 Rad52/22 family double-strand break repair protein Ribosomal_L21e PF01157.13 AFZ78973.1 - 8.8e-38 128.1 1.7 1.2e-37 127.6 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e NAC PF01849.13 AFZ78974.1 - 1.6e-19 69.1 0.0 2.6e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 NAC domain WW PF00397.21 AFZ78975.1 - 3.6e-06 26.7 0.3 3.6e-06 26.7 0.2 1.9 2 0 0 2 2 2 1 WW domain Ribosomal_L16 PF00252.13 AFZ78976.1 - 3.5e-31 107.7 0.1 4.7e-31 107.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e KOW PF00467.24 AFZ78977.1 - 3.4e-05 23.3 0.4 6.7e-05 22.4 0.3 1.5 1 0 0 1 1 1 1 KOW motif Rep_fac-A_C PF08646.5 AFZ78978.1 - 6.9e-30 103.6 0.0 2.3e-29 102.0 0.0 1.8 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 AFZ78978.1 - 3.4e-12 46.0 0.1 8.9e-09 35.0 0.0 3.1 2 1 1 3 3 3 2 OB-fold nucleic acid binding domain Asparaginase_2 PF01112.13 AFZ78978.1 - 0.046 12.4 0.3 0.17 10.5 0.0 1.9 2 0 0 2 2 2 0 Asparaginase CTDII PF01556.13 AFZ78979.1 - 2e-30 104.5 2.3 1e-19 70.1 0.0 3.4 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 AFZ78979.1 - 1.3e-24 85.6 1.3 2.7e-24 84.6 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 AFZ78979.1 - 6.4e-11 42.1 11.6 6.4e-11 42.1 8.0 1.9 2 0 0 2 2 2 1 DnaJ central domain Peptidase_C1 PF00112.18 AFZ78980.1 - 5.3e-54 183.4 7.6 8.8e-54 182.6 5.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 AFZ78980.1 - 5.7e-08 32.9 3.2 1.6e-07 31.4 2.2 1.8 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 AFZ78980.1 - 3.3e-06 25.9 1.8 5.6e-06 25.1 0.7 1.8 2 0 0 2 2 2 1 Peptidase C1-like family zf-C2H2_2 PF12756.2 AFZ78981.1 - 9.3e-25 86.6 6.9 2.8e-22 78.7 1.7 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 AFZ78981.1 - 4.3e-07 29.8 8.3 0.0025 17.8 0.4 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AFZ78981.1 - 0.017 15.2 7.8 0.3 11.3 0.5 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 AFZ78981.1 - 0.41 11.0 9.3 0.85 10.0 0.7 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type DNA_pol_A_exo1 PF01612.15 AFZ78982.1 - 1.1e-20 73.7 0.1 1.7e-20 73.2 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DUF3985 PF13153.1 AFZ78982.1 - 0.12 12.2 0.3 0.28 11.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3985) HTH_22 PF13309.1 AFZ78983.1 - 0.09 12.5 3.0 0.37 10.5 0.0 2.8 2 1 1 3 3 3 0 HTH domain RNA_pol_Rpc34 PF05158.7 AFZ78983.1 - 0.093 11.9 0.1 0.093 11.9 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase Rpc34 subunit AsiA PF09010.5 AFZ78983.1 - 0.31 10.9 3.0 2.4 8.0 0.1 2.9 3 0 0 3 3 3 0 Anti-Sigma Factor A YIF1 PF03878.10 AFZ78984.1 - 1.2e-06 27.9 2.7 0.0068 15.5 0.1 2.3 2 0 0 2 2 2 2 YIF1 LSM PF01423.17 AFZ78985.1 - 4.2e-16 58.2 0.1 5.5e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain AMP-binding PF00501.23 AFZ78986.1 - 2.3e-67 227.2 0.0 3.1e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Terminase_6 PF03237.10 AFZ78986.1 - 0.091 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family Phi-29_GP4 PF05464.6 AFZ78988.1 - 0.091 12.6 0.2 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) HUN PF08729.5 AFZ78989.1 - 7.6e-12 44.9 2.4 7.6e-12 44.9 1.6 2.9 3 0 0 3 3 3 1 HPC2 and ubinuclein domain MCM PF00493.18 AFZ78991.1 - 9.1e-131 435.5 0.0 1.3e-130 435.0 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AFZ78991.1 - 7.9e-14 52.1 4.1 1.3e-13 51.5 0.5 2.8 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 AFZ78991.1 - 0.00011 21.4 0.0 0.00029 20.0 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AFZ78991.1 - 0.0019 17.9 0.0 0.017 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Desulfoferrod_N PF06397.7 AFZ78991.1 - 0.069 12.5 0.3 0.16 11.3 0.2 1.6 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Mg_chelatase_2 PF13335.1 AFZ78991.1 - 0.11 12.9 0.1 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NurA PF09376.5 AFZ78992.1 - 0.085 12.3 0.1 0.097 12.1 0.1 1.2 1 0 0 1 1 1 0 NurA domain UCH PF00443.24 AFZ78994.1 - 4.9e-44 150.4 3.0 6.7e-44 150.0 2.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AFZ78994.1 - 5.5e-29 101.5 2.1 3e-28 99.1 1.5 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PIG-X PF08320.7 AFZ78995.1 - 0.0089 15.3 1.7 0.69 9.1 0.0 2.7 2 1 0 2 2 2 2 PIG-X / PBN1 SMC_N PF02463.14 AFZ78997.1 - 5.6e-71 238.2 8.1 1.6e-70 236.8 5.6 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AFZ78997.1 - 2.8e-25 88.5 0.3 1.1e-24 86.6 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 AFZ78997.1 - 9.7e-13 48.9 10.7 9.7e-13 48.9 7.4 6.9 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 AFZ78997.1 - 6.3e-11 42.7 13.3 3.2e-07 30.5 1.3 6.3 4 2 2 7 7 7 2 AAA domain AAA_29 PF13555.1 AFZ78997.1 - 2.7e-06 26.7 0.0 5.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 AFZ78997.1 - 0.042 14.1 0.0 0.042 14.1 0.0 5.9 5 1 0 5 5 5 0 ABC transporter Reo_sigmaC PF04582.7 AFZ78997.1 - 0.12 11.5 39.0 0.11 11.5 1.8 6.1 3 2 3 7 7 7 0 Reovirus sigma C capsid protein DUF3407 PF11887.3 AFZ78997.1 - 7.4 5.7 10.6 22 4.2 0.7 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3407) RNA_pol_Rpc4 PF05132.9 AFZ78998.1 - 9.1e-17 61.2 0.0 8e-16 58.2 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase III RPC4 Trefoil PF00088.13 AFZ78998.1 - 0.095 12.3 1.6 0.87 9.2 0.3 2.4 2 0 0 2 2 2 0 Trefoil (P-type) domain Kelch_3 PF13415.1 AFZ78999.1 - 6.2e-27 93.0 5.2 2.3e-08 33.9 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 AFZ78999.1 - 2.3e-21 75.3 0.7 6.7e-05 22.7 0.0 6.7 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 AFZ78999.1 - 3.5e-20 71.4 11.5 3.7e-05 23.3 0.0 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 AFZ78999.1 - 8e-13 47.9 8.0 0.0072 16.4 0.1 5.6 5 1 1 6 6 6 4 Kelch motif HATPase_c_3 PF13589.1 AFZ78999.1 - 3.8e-10 39.5 0.0 8.2e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_1 PF01344.20 AFZ78999.1 - 1.2e-09 37.5 1.0 0.0013 18.2 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 AFZ78999.1 - 1.3e-08 34.2 2.2 5.9e-05 22.6 0.0 4.1 4 0 0 4 4 4 2 Kelch motif HATPase_c PF02518.21 AFZ78999.1 - 8.2e-08 31.9 0.0 1.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CCCH PF00642.19 AFZ79000.1 - 0.0014 18.2 17.3 0.029 14.0 2.2 4.0 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AFZ79000.1 - 0.039 13.9 0.6 0.039 13.9 0.4 4.6 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type Fer4_20 PF14691.1 AFZ79000.1 - 0.07 12.7 2.8 0.15 11.6 1.9 1.6 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DER1 PF04511.10 AFZ79001.1 - 7.2e-40 136.5 15.2 8.2e-40 136.4 10.5 1.0 1 0 0 1 1 1 1 Der1-like family EGF_MSP1_1 PF12946.2 AFZ79002.1 - 0.091 12.5 5.0 0.25 11.1 3.5 1.8 1 0 0 1 1 1 0 MSP1 EGF domain 1 EB PF01683.13 AFZ79002.1 - 6.7 6.8 13.5 0.56 10.3 3.8 2.5 2 0 0 2 2 2 0 EB module DEAD PF00270.24 AFZ79003.1 - 1.1e-39 135.6 1.6 1.4e-39 135.3 0.3 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ79003.1 - 5.1e-28 96.7 0.3 4.4e-27 93.7 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_RecD PF05127.9 AFZ79003.1 - 0.00083 19.0 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Helicase ResIII PF04851.10 AFZ79003.1 - 0.0016 18.3 0.1 0.0083 15.9 0.1 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AFZ79003.1 - 0.004 16.8 0.0 0.0096 15.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 AFZ79003.1 - 0.006 16.1 0.0 0.017 14.7 0.0 1.7 2 1 0 2 2 2 1 AAA domain tRNA-synt_1b PF00579.20 AFZ79003.1 - 0.0063 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CMS1 PF14617.1 AFZ79003.1 - 0.016 14.2 0.1 0.048 12.7 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 AFZ79003.1 - 0.068 13.3 0.2 0.3 11.2 0.2 2.2 1 1 0 1 1 1 0 AAA domain tRNA_bind PF01588.15 AFZ79004.1 - 1.2e-28 98.7 0.0 2e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.20 AFZ79004.1 - 6.7e-08 32.4 0.0 1.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AFZ79004.1 - 0.00078 19.8 0.2 0.0021 18.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain His_Phos_1 PF00300.17 AFZ79005.1 - 4.1e-10 39.9 0.0 6.6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) COPI_assoc PF08507.5 AFZ79008.1 - 0.0078 15.8 5.5 0.015 14.9 3.5 1.6 2 0 0 2 2 2 1 COPI associated protein DUF2516 PF10724.4 AFZ79008.1 - 0.44 10.5 3.9 0.26 11.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) DUF4231 PF14015.1 AFZ79008.1 - 0.98 9.4 3.3 2.6 8.0 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Asp_protease PF09668.5 AFZ79009.1 - 1.9e-40 137.2 0.3 3.3e-40 136.4 0.2 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 AFZ79009.1 - 3.6e-13 49.8 0.1 8.4e-13 48.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 AFZ79009.1 - 1.4e-09 37.7 1.0 1.3e-08 34.6 0.2 2.6 3 1 0 3 3 3 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 AFZ79009.1 - 2.2e-09 37.0 0.0 5e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.18 AFZ79009.1 - 2.6e-06 26.7 0.4 6.1e-06 25.5 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.6 AFZ79009.1 - 4e-05 23.5 0.1 0.00016 21.6 0.1 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 AFZ79009.1 - 0.00057 19.5 0.2 0.0013 18.3 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 AFZ79009.1 - 0.0021 17.8 0.0 0.0072 16.1 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 AFZ79009.1 - 0.0036 16.7 0.0 0.011 15.3 0.0 1.9 1 0 0 1 1 1 1 UBA-like domain Peptidase_A2B PF12384.3 AFZ79009.1 - 0.0073 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Ty3 transposon peptidase YccV-like PF08755.6 AFZ79009.1 - 0.22 11.4 1.4 0.63 10.0 0.3 2.3 1 1 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like DUF676 PF05057.9 AFZ79010.1 - 4.2e-21 75.2 0.1 6.5e-21 74.6 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 AFZ79010.1 - 8.5e-09 35.3 0.0 9.7e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 AFZ79010.1 - 4.3e-07 29.2 0.1 5.5e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 AFZ79010.1 - 0.0024 17.4 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 AFZ79010.1 - 0.007 15.9 0.0 0.02 14.5 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) DUF900 PF05990.7 AFZ79010.1 - 0.0071 15.7 0.0 0.0082 15.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.2 AFZ79010.1 - 0.0092 15.8 0.0 0.01 15.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family SUKH_5 PF14567.1 AFZ79010.1 - 0.031 13.7 0.1 0.056 12.8 0.1 1.5 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Abhydrolase_5 PF12695.2 AFZ79010.1 - 0.038 13.7 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4030 PF13222.1 AFZ79010.1 - 0.041 13.6 0.5 0.041 13.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4030) Cytochrome_cB PF11783.3 AFZ79011.1 - 0.061 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c bacterial S4 PF01479.20 AFZ79011.1 - 0.38 10.2 4.3 7.1 6.1 0.3 3.4 3 0 0 3 3 3 0 S4 domain RAP PF08373.5 AFZ79013.1 - 1.3e-14 53.7 0.3 5.3e-14 51.7 0.2 2.1 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.10 AFZ79013.1 - 0.02 14.5 4.5 1.1 9.0 0.1 5.2 5 1 1 6 6 6 0 FAST kinase-like protein, subdomain 1 Cor1 PF04803.7 AFZ79013.1 - 0.022 14.5 5.7 0.17 11.6 2.7 2.9 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Mic1 PF07035.7 AFZ79014.1 - 6.6e-07 28.8 5.5 1.8e-06 27.4 3.8 1.8 1 1 0 1 1 1 1 Colon cancer-associated protein Mic1-like UreE_C PF05194.7 AFZ79015.1 - 0.085 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain PK PF00224.16 AFZ79017.1 - 3e-87 292.4 0.2 1.6e-47 161.8 0.0 2.3 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.11 AFZ79017.1 - 0.00014 21.4 0.0 0.00028 20.4 0.0 1.4 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.20 AFZ79017.1 - 0.095 11.5 0.7 2 7.1 0.1 2.4 2 1 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain S4 PF01479.20 AFZ79019.1 - 0.00012 21.3 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain PseudoU_synth_2 PF00849.17 AFZ79019.1 - 0.003 17.3 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase potato_inhibit PF00280.13 AFZ79019.1 - 0.045 13.9 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Potato inhibitor I family DUF3091 PF11291.3 AFZ79020.1 - 0.006 16.5 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3091) Pkinase PF00069.20 AFZ79022.1 - 4.1e-62 209.6 0.7 1.2e-61 208.1 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ79022.1 - 1.4e-34 119.3 0.1 2.5e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AFZ79022.1 - 1.5e-06 27.3 0.1 3.5e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AFZ79022.1 - 0.0031 17.2 0.0 0.56 9.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Peptidase_C1 PF00112.18 AFZ79023.1 - 7e-37 127.4 0.1 2.9e-36 125.3 0.0 2.0 2 1 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 AFZ79023.1 - 2.7e-09 37.1 10.0 5.8e-09 36.0 6.9 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 AFZ79023.1 - 0.012 14.2 0.9 0.022 13.2 0.0 1.8 2 0 0 2 2 2 0 Peptidase C1-like family Mito_carr PF00153.22 AFZ79024.1 - 9.9e-66 217.5 4.1 4.2e-24 84.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Myf5 PF12232.3 AFZ79024.1 - 0.067 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Myogenic determination factor 5 ubiquitin PF00240.18 AFZ79025.1 - 7.9e-25 86.0 0.4 3.3e-24 84.0 0.8 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 AFZ79025.1 - 6.5e-13 48.1 1.4 1.1e-12 47.4 1.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 AFZ79025.1 - 0.00021 21.1 0.3 0.00053 19.8 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AFZ79025.1 - 0.0051 16.9 0.6 0.027 14.6 0.1 2.0 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 AFZ79025.1 - 0.0069 16.6 1.1 0.025 14.8 0.7 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain TUG-UBL1 PF11470.3 AFZ79025.1 - 0.011 15.6 0.2 0.019 14.8 0.2 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG GABP-alpha PF11620.3 AFZ79025.1 - 0.013 15.4 0.2 1.5 8.8 0.3 2.3 1 1 1 2 2 2 0 GA-binding protein alpha chain DUF2604 PF10790.4 AFZ79025.1 - 0.017 15.2 0.0 0.074 13.1 0.1 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF2604) DUF743 PF05332.6 AFZ79025.1 - 0.062 13.2 0.4 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF743) ThiS PF02597.15 AFZ79025.1 - 0.063 13.7 0.2 0.1 13.0 0.1 1.4 1 0 0 1 1 1 0 ThiS family Dynamin_M PF01031.15 AFZ79026.1 - 3.2e-91 305.1 0.1 6e-91 304.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 AFZ79026.1 - 4.8e-49 166.3 0.1 1.4e-48 164.8 0.1 1.9 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 AFZ79026.1 - 5.3e-30 103.1 3.8 1.8e-29 101.4 2.6 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 AFZ79026.1 - 3.8e-06 26.8 0.8 0.00017 21.5 0.5 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AFZ79026.1 - 0.068 13.1 0.0 0.24 11.3 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain Condensin2nSMC PF12422.3 AFZ79026.1 - 0.076 12.7 3.7 0.044 13.5 0.8 1.9 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Helicase_C_3 PF13625.1 AFZ79027.1 - 3.1e-19 69.0 0.0 8.4e-19 67.6 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ79027.1 - 1.3e-14 54.4 0.0 1.3e-14 54.4 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AFZ79027.1 - 1.2e-11 44.3 0.0 8e-11 41.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AFZ79027.1 - 2.5e-07 29.7 0.1 4.6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3139 PF11337.3 AFZ79028.1 - 0.04 14.2 1.4 0.41 10.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Radical_SAM PF04055.16 AFZ79029.1 - 7.4e-12 45.7 2.4 3.4e-11 43.6 1.7 2.1 1 1 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 AFZ79029.1 - 5.6e-05 23.0 0.1 0.00057 19.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family HSP70 PF00012.15 AFZ79031.1 - 5.8e-264 876.5 7.9 6.6e-264 876.3 5.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AFZ79031.1 - 6.3e-16 57.8 0.2 1.9e-14 53.0 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 AFZ79031.1 - 6.8e-05 21.8 0.5 0.0046 15.8 0.2 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 AFZ79031.1 - 0.0034 17.0 0.0 0.016 14.7 0.0 2.2 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 AFZ79031.1 - 0.026 13.6 1.4 0.2 10.7 0.1 2.8 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase FtsA PF14450.1 AFZ79031.1 - 0.033 14.0 5.6 0.5 10.2 0.4 4.0 2 2 0 2 2 2 0 Cell division protein FtsA APP_N PF02177.11 AFZ79031.1 - 0.09 12.7 0.7 0.23 11.3 0.5 1.6 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding zf-C3HC4_2 PF13923.1 AFZ79032.1 - 4.9e-08 32.8 19.2 1.5e-07 31.2 13.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AFZ79032.1 - 1.2e-07 31.2 20.1 4.7e-07 29.3 13.9 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AFZ79032.1 - 1.8e-07 30.7 17.4 5.1e-07 29.2 12.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AFZ79032.1 - 8.6e-07 28.5 20.0 2.6e-06 27.0 13.9 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 AFZ79032.1 - 1.1e-06 28.3 17.0 3.9e-06 26.5 11.8 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 AFZ79032.1 - 0.0011 18.8 16.1 0.003 17.3 11.2 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AFZ79032.1 - 0.024 14.3 13.5 0.087 12.5 9.3 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 AFZ79032.1 - 0.053 13.1 15.4 0.14 11.7 10.6 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HALZ PF02183.13 AFZ79032.1 - 0.33 10.6 23.3 3.8 7.3 4.4 5.2 3 1 0 3 3 3 0 Homeobox associated leucine zipper zf-RING_6 PF14835.1 AFZ79032.1 - 0.62 9.8 12.4 0.1 12.3 5.7 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Herpes_UL51 PF04540.8 AFZ79032.1 - 1.5 8.3 6.2 8.2 5.9 0.0 3.1 3 0 0 3 3 3 0 Herpesvirus UL51 protein Beta-Casp PF10996.3 AFZ79033.1 - 3.9e-11 42.9 0.3 1.4e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain CPSF100_C PF13299.1 AFZ79033.1 - 8.5e-07 29.2 0.3 9.5e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B_2 PF12706.2 AFZ79033.1 - 0.00011 21.8 0.3 0.00019 21.0 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AFZ79033.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily AAA_23 PF13476.1 AFZ79035.1 - 4.4e-19 69.6 18.2 4.4e-19 69.6 12.6 6.8 1 1 4 5 5 2 1 AAA domain SMC_N PF02463.14 AFZ79035.1 - 1.6e-13 50.4 9.5 8.9e-09 34.8 3.3 3.7 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 AFZ79035.1 - 1.5e-08 34.4 0.0 6.6e-08 32.3 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 AFZ79035.1 - 8.9e-07 28.2 22.9 2.8e-06 26.6 1.4 5.3 2 1 2 4 4 2 2 AAA ATPase domain AAA_21 PF13304.1 AFZ79035.1 - 8.2e-06 25.9 0.7 8.2e-06 25.9 0.5 6.3 1 1 1 3 3 1 1 AAA domain AAA_29 PF13555.1 AFZ79035.1 - 0.00042 19.7 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 AFZ79035.1 - 0.0011 17.5 0.3 0.0011 17.5 0.2 6.4 2 1 3 6 6 5 3 AAA domain ABC_tran PF00005.22 AFZ79035.1 - 0.0023 18.2 0.0 0.0023 18.2 0.0 5.6 3 2 0 3 3 1 1 ABC transporter AAA_16 PF13191.1 AFZ79035.1 - 0.022 14.7 0.0 0.066 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 AFZ79035.1 - 0.031 14.1 0.1 0.18 11.6 0.0 2.5 2 0 0 2 2 1 0 AAA domain PuR_N PF09182.5 AFZ79035.1 - 0.042 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal AAA_19 PF13245.1 AFZ79035.1 - 0.12 12.0 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain DUF1925 PF09094.6 AFZ79035.1 - 0.53 10.3 4.4 1.8 8.6 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1925) AAA_22 PF13401.1 AFZ79035.1 - 0.64 10.1 0.0 0.64 10.1 0.0 4.5 5 2 0 5 5 5 0 AAA domain DUF3782 PF12644.2 AFZ79035.1 - 1.1 9.1 0.0 1.1 9.1 0.0 5.2 4 2 0 4 4 3 0 Protein of unknown function (DUF3782) RRM_1 PF00076.17 AFZ79036.1 - 3.9e-25 87.2 0.0 4e-12 45.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ79036.1 - 2.5e-21 75.3 0.0 1.3e-09 37.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ79036.1 - 3.6e-07 29.9 0.0 4.9e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.21 AFZ79037.1 - 1.8e-40 137.6 0.0 1.9e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AFZ79037.1 - 0.069 13.0 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain Coatomer_WDAD PF04053.9 AFZ79038.1 - 8.8e-81 271.9 9.7 1.4e-80 271.2 6.7 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 AFZ79038.1 - 8.6e-46 152.2 17.1 1.5e-09 37.3 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat COPI_C PF06957.6 AFZ79038.1 - 5e-33 114.2 1.1 7.6e-33 113.6 0.8 1.3 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Nup160 PF11715.3 AFZ79038.1 - 0.0033 15.6 7.6 0.11 10.5 0.1 3.2 2 2 2 4 4 4 2 Nucleoporin Nup120/160 Clathrin PF00637.15 AFZ79038.1 - 0.0087 15.6 0.2 0.088 12.4 0.0 2.7 2 1 1 3 3 3 1 Region in Clathrin and VPS AP2 PF00847.15 AFZ79039.1 - 2.6e-06 27.4 0.8 2.6e-06 27.4 0.6 2.7 3 0 0 3 3 3 2 AP2 domain XRN_N PF03159.13 AFZ79041.1 - 1e-78 264.0 0.0 2.8e-78 262.5 0.0 1.8 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus MACPF PF01823.14 AFZ79042.1 - 2.7e-34 118.7 6.5 2.7e-34 118.7 4.5 3.0 3 1 0 3 3 3 1 MAC/Perforin domain tRNA-synt_2d PF01409.15 AFZ79043.1 - 1.4e-36 125.9 0.6 1.1e-20 73.9 0.0 3.2 2 1 1 3 3 3 3 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 AFZ79043.1 - 7.9e-17 61.2 0.0 1.5e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 AFZ79043.1 - 0.018 13.8 0.9 0.41 9.3 0.1 2.3 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) C2 PF00168.25 AFZ79044.1 - 1.1e-07 31.5 0.0 5.8e-06 26.0 0.0 2.9 2 0 0 2 2 2 1 C2 domain DHO_dh PF01180.16 AFZ79045.1 - 1.6e-92 309.6 0.8 1.8e-92 309.4 0.6 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.10 AFZ79045.1 - 0.0049 16.0 0.0 0.0064 15.6 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase PcrB PF01884.12 AFZ79045.1 - 0.018 14.2 0.0 0.16 11.1 0.0 2.1 2 0 0 2 2 2 0 PcrB family His_biosynth PF00977.16 AFZ79045.1 - 0.04 13.1 0.0 0.088 12.0 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.9 AFZ79045.1 - 0.044 12.7 0.0 0.14 11.0 0.0 1.8 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.9 AFZ79045.1 - 0.049 12.7 0.2 0.21 10.6 0.0 1.9 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.12 AFZ79045.1 - 0.14 11.2 0.3 3 6.9 0.0 2.7 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI AAA PF00004.24 AFZ79046.1 - 6.7e-53 178.4 0.0 2.1e-39 134.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AFZ79046.1 - 1.5e-11 44.1 0.0 3.1e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.1 AFZ79046.1 - 1.4e-10 41.4 3.7 0.0019 18.3 0.5 4.6 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 AFZ79046.1 - 5.7e-10 39.0 0.0 1.4e-05 24.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AFZ79046.1 - 6e-09 35.9 0.0 0.0027 17.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AFZ79046.1 - 1.7e-08 35.2 0.0 0.0019 19.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AFZ79046.1 - 4.9e-08 33.1 0.9 0.0036 17.3 0.0 2.8 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 AFZ79046.1 - 8.8e-08 31.2 0.0 0.002 16.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 AFZ79046.1 - 1.4e-07 31.4 0.0 0.018 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 AFZ79046.1 - 4.6e-07 29.9 0.0 5.4e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 AFZ79046.1 - 3.5e-06 26.6 0.6 0.011 15.4 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 AFZ79046.1 - 9.3e-06 24.9 0.0 0.0049 16.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AFZ79046.1 - 1.1e-05 25.7 0.0 0.0093 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AFZ79046.1 - 1.3e-05 24.8 0.3 0.12 12.0 0.0 3.1 3 1 0 3 3 2 2 NACHT domain AAA_25 PF13481.1 AFZ79046.1 - 5.1e-05 22.7 0.1 0.015 14.7 0.0 3.2 2 2 1 3 3 3 1 AAA domain Sigma54_activat PF00158.21 AFZ79046.1 - 5.2e-05 22.7 0.0 0.32 10.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 AFZ79046.1 - 5.5e-05 22.9 0.2 3.3 7.3 0.1 4.1 2 2 1 4 4 4 1 Archaeal ATPase RuvB_N PF05496.7 AFZ79046.1 - 0.0001 21.4 0.1 0.017 14.2 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 AFZ79046.1 - 0.00014 22.0 0.0 0.036 14.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 AFZ79046.1 - 0.00014 21.0 0.0 0.048 12.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 AFZ79046.1 - 0.00087 19.2 0.0 0.33 10.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 AFZ79046.1 - 0.0016 17.3 0.1 0.68 8.7 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain DUF2075 PF09848.4 AFZ79046.1 - 0.0026 16.7 0.0 0.032 13.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 AFZ79046.1 - 0.0036 17.3 0.1 2.8 7.9 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain UPF0079 PF02367.12 AFZ79046.1 - 0.0056 16.2 0.1 1 8.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 AFZ79046.1 - 0.006 15.7 0.1 0.062 12.4 0.0 2.3 2 0 0 2 2 2 1 KaiC IstB_IS21 PF01695.12 AFZ79046.1 - 0.0063 15.9 0.0 0.13 11.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.1 AFZ79046.1 - 0.011 15.3 0.2 0.12 11.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 AFZ79046.1 - 0.013 14.3 0.0 2.5 6.7 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Parvo_NS1 PF01057.12 AFZ79046.1 - 0.013 14.3 0.0 0.092 11.5 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 AFZ79046.1 - 0.015 15.6 0.2 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 ABC transporter DAP3 PF10236.4 AFZ79046.1 - 0.027 13.4 0.1 0.67 8.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 SKI PF01202.17 AFZ79046.1 - 0.033 14.0 0.1 2.2 8.1 0.1 2.7 2 1 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.1 AFZ79046.1 - 0.039 13.4 0.6 1.6 8.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain DNA_pol3_delta2 PF13177.1 AFZ79046.1 - 0.042 13.5 0.0 0.37 10.4 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III, delta subunit PhoH PF02562.11 AFZ79046.1 - 0.05 12.8 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Torsin PF06309.6 AFZ79046.1 - 0.065 13.1 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Torsin DUF815 PF05673.8 AFZ79046.1 - 0.067 12.1 0.1 1.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 AFZ79046.1 - 0.094 12.2 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 AFZ79046.1 - 0.097 12.2 0.2 0.76 9.3 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.6 AFZ79046.1 - 0.11 12.1 0.0 0.68 9.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 AFZ79046.1 - 0.11 12.3 0.0 16 5.2 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.4 AFZ79046.1 - 0.14 10.7 0.0 6.4 5.2 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Sterile PF03015.14 AFZ79047.1 - 0.38 11.0 2.9 1 9.6 0.1 2.8 3 0 0 3 3 3 0 Male sterility protein CRM1_C PF08767.6 AFZ79048.1 - 6.5e-97 324.2 3.9 6.5e-97 324.2 2.7 2.8 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 AFZ79048.1 - 3.7e-33 114.5 2.8 3.7e-33 114.5 1.9 4.9 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 AFZ79048.1 - 4.6e-12 45.6 0.4 2e-11 43.6 0.2 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Pkinase PF00069.20 AFZ79049.1 - 1.1e-46 159.1 0.1 3.9e-46 157.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ79049.1 - 5.7e-21 74.7 0.0 2.2e-20 72.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AFZ79049.1 - 0.0028 16.6 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF1748 PF08520.5 AFZ79049.1 - 0.053 13.1 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1748) TYW3 PF02676.9 AFZ79050.1 - 2.6e-35 121.4 0.3 5.3e-35 120.4 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase TYW3 Met_10 PF02475.11 AFZ79050.1 - 8.7e-19 67.9 0.2 2.7e-18 66.3 0.1 1.8 1 1 0 1 1 1 1 Met-10+ like-protein Kelch_4 PF13418.1 AFZ79050.1 - 1.2e-10 40.9 6.5 0.0087 15.8 0.0 4.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 AFZ79050.1 - 1.7e-10 40.6 3.4 0.025 14.5 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 AFZ79050.1 - 8.5e-07 28.9 1.5 0.012 15.7 0.0 4.7 4 0 0 4 4 4 1 Galactose oxidase, central domain Methyltransf_31 PF13847.1 AFZ79050.1 - 0.00039 20.0 0.0 0.0018 17.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AFZ79050.1 - 0.0028 17.0 0.0 0.0068 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 AFZ79050.1 - 0.042 12.8 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_26 PF13659.1 AFZ79050.1 - 0.084 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PHF5 PF03660.9 AFZ79051.1 - 2.9e-47 159.1 15.3 3.6e-47 158.8 10.6 1.0 1 0 0 1 1 1 1 PHF5-like protein GTP_EFTU PF00009.22 AFZ79052.1 - 2.9e-31 108.3 0.0 2.9e-31 108.3 0.0 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 AFZ79052.1 - 1.1e-18 67.1 0.3 1.1e-18 67.1 0.2 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 AFZ79052.1 - 8.5e-14 51.4 5.8 6.4e-10 39.0 0.2 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 AFZ79052.1 - 6.2e-07 28.9 1.2 9.6e-07 28.3 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 AFZ79052.1 - 2.2e-06 27.6 1.6 2.7e-05 24.0 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 AFZ79052.1 - 0.0037 16.8 0.0 0.015 14.8 0.0 2.1 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 AFZ79052.1 - 0.0066 16.5 0.0 0.048 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain zf-RING_2 PF13639.1 AFZ79053.1 - 8.3e-13 47.9 5.5 8.3e-13 47.9 3.8 2.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 AFZ79053.1 - 3.1e-08 33.5 6.9 3.1e-08 33.5 4.8 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AFZ79053.1 - 1.1e-07 31.4 6.5 1.1e-07 31.4 4.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AFZ79053.1 - 3.4e-07 29.8 3.8 3.4e-07 29.8 2.6 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 AFZ79053.1 - 1.1e-06 28.5 5.4 3.3e-06 27.1 3.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 AFZ79053.1 - 3.1e-05 23.5 5.6 3.1e-05 23.5 3.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 AFZ79053.1 - 0.00029 20.8 5.8 0.00029 20.8 4.0 2.2 2 0 0 2 2 2 1 RING-variant domain zf-Apc11 PF12861.2 AFZ79053.1 - 0.0066 16.2 4.2 0.008 15.9 1.8 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 AFZ79053.1 - 0.018 14.8 4.7 0.04 13.7 3.3 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FANCL_C PF11793.3 AFZ79053.1 - 0.098 12.6 10.0 0.086 12.8 4.4 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 AFZ79053.1 - 0.98 9.0 9.2 0.25 10.9 3.7 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF2244 PF10003.4 AFZ79053.1 - 1.2 8.5 5.4 1.8 7.9 0.2 2.9 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) EXS PF03124.9 AFZ79054.1 - 3.4e-59 200.6 21.6 4.9e-59 200.1 14.9 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 AFZ79054.1 - 1.8e-16 60.7 4.5 1.2e-15 58.0 3.1 2.1 1 1 0 1 1 1 1 SPX domain AIP3 PF03915.8 AFZ79054.1 - 0.024 13.5 1.0 0.034 13.0 0.7 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 WD40 PF00400.27 AFZ79055.1 - 1.5e-08 34.1 4.6 6e-05 22.7 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat SUKH_5 PF14567.1 AFZ79055.1 - 0.0037 16.7 0.4 0.73 9.2 0.1 2.3 2 0 0 2 2 2 2 SMI1-KNR4 cell-wall DUF150 PF02576.12 AFZ79056.1 - 0.022 14.3 0.5 0.041 13.4 0.3 1.5 1 1 0 1 1 1 0 Uncharacterised BCR, YhbC family COG0779 GYF PF02213.11 AFZ79057.1 - 1.2e-15 56.8 5.7 1.2e-15 56.8 3.9 1.9 2 0 0 2 2 2 1 GYF domain PAE PF03283.8 AFZ79058.1 - 0.0035 16.0 0.0 0.0044 15.6 0.0 1.1 1 0 0 1 1 1 1 Pectinacetylesterase KOW PF00467.24 AFZ79058.1 - 0.0083 15.8 3.8 0.023 14.4 2.6 1.9 1 1 0 1 1 1 1 KOW motif Cyclin_N PF00134.18 AFZ79060.1 - 2.9e-09 36.5 0.2 6.7e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.20 AFZ79061.1 - 9.4e-59 198.6 0.0 1.1e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ79061.1 - 2.7e-35 121.6 0.0 3.4e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AFZ79061.1 - 1.2e-06 27.7 0.1 1.7e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AFZ79061.1 - 0.00012 21.2 0.1 0.00019 20.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Acylphosphatase PF00708.13 AFZ79062.1 - 0.0042 17.1 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 Acylphosphatase Glutaredoxin PF00462.19 AFZ79064.1 - 3e-17 62.3 0.0 7.2e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin ArsC PF03960.10 AFZ79064.1 - 0.00096 19.2 0.0 0.2 11.7 0.0 2.9 3 0 0 3 3 3 1 ArsC family Thioredoxin_6 PF13848.1 AFZ79064.1 - 0.0018 18.1 0.1 0.027 14.3 0.0 2.1 1 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.15 AFZ79064.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin TnpW PF14202.1 AFZ79064.1 - 0.03 13.8 0.1 0.054 13.1 0.1 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpW Ligase_CoA PF00549.14 AFZ79064.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 CoA-ligase PAD_porph PF04371.10 AFZ79064.1 - 0.13 11.3 0.0 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Porphyromonas-type peptidyl-arginine deiminase Methyltransf_23 PF13489.1 AFZ79065.1 - 3.7e-24 85.2 0.0 5.1e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AFZ79065.1 - 7.5e-16 58.0 1.0 4.6e-15 55.5 0.3 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AFZ79065.1 - 7.5e-16 58.6 0.0 1.9e-15 57.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AFZ79065.1 - 2.9e-15 56.5 0.0 5.2e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AFZ79065.1 - 4.1e-14 52.8 0.0 7.7e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AFZ79065.1 - 9.2e-10 38.0 0.1 2.2e-09 36.8 0.1 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 AFZ79065.1 - 2.8e-09 37.2 0.0 1.1e-08 35.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AFZ79065.1 - 8.8e-08 32.1 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 AFZ79065.1 - 1.4e-06 27.8 0.0 7.7e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 AFZ79065.1 - 7.1e-05 21.9 0.0 0.0001 21.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 AFZ79065.1 - 0.00012 21.7 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AFZ79065.1 - 0.00014 21.0 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 AFZ79065.1 - 0.0005 19.6 0.0 0.0013 18.2 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.13 AFZ79065.1 - 0.0014 17.9 0.4 0.0043 16.3 0.2 1.8 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_PK PF05891.7 AFZ79065.1 - 0.0018 17.6 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_4 PF02390.12 AFZ79065.1 - 0.0022 17.0 0.0 0.08 11.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 AFZ79065.1 - 0.0047 16.3 0.0 0.0089 15.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 AFZ79065.1 - 0.0062 16.1 0.1 0.012 15.1 0.1 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.7 AFZ79065.1 - 0.0094 15.3 0.1 0.022 14.1 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 AFZ79065.1 - 0.011 14.4 0.1 0.018 13.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) 3HCDH_N PF02737.13 AFZ79065.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDCD2_C PF04194.8 AFZ79066.1 - 1.6e-11 44.0 0.2 2.3e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Topoisom_I PF01028.15 AFZ79067.1 - 8.1e-94 313.1 5.8 8.1e-94 313.1 4.0 2.2 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.10 AFZ79067.1 - 4.6e-76 254.8 5.9 4.6e-76 254.8 4.1 2.6 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.1 AFZ79067.1 - 2.6e-32 110.3 1.0 2.6e-32 110.3 0.7 2.4 2 0 0 2 2 2 1 C-terminal topoisomerase domain Bromodomain PF00439.20 AFZ79068.1 - 3.5e-13 49.2 0.4 2.7e-12 46.4 0.0 2.4 2 0 0 2 2 2 1 Bromodomain DUF1281 PF06924.6 AFZ79068.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) TEX12 PF15219.1 AFZ79068.1 - 0.076 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Testis-expressed 12 PIP5K PF01504.13 AFZ79069.1 - 1.6e-73 246.9 0.6 3.2e-73 245.9 0.3 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_8 PF13833.1 AFZ79069.1 - 0.0014 18.2 1.4 0.0057 16.2 0.1 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 AFZ79069.1 - 0.0041 16.3 4.2 0.0048 16.1 0.2 3.0 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 AFZ79069.1 - 0.0056 16.4 0.3 0.34 10.9 0.3 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 AFZ79069.1 - 0.006 16.7 0.3 0.27 11.3 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 AFZ79069.1 - 0.017 14.4 0.4 0.039 13.3 0.2 1.6 1 0 0 1 1 1 0 EF hand JAB PF01398.16 AFZ79070.1 - 1.4e-33 115.0 0.0 2.7e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 AFZ79070.1 - 1.5e-22 79.8 2.8 2.6e-22 79.0 1.9 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 AFZ79070.1 - 8.8e-10 38.0 0.0 1.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Phage_GP20 PF06810.6 AFZ79070.1 - 0.068 12.6 1.4 0.1 12.0 1.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Tox-SHH PF15652.1 AFZ79070.1 - 0.11 13.0 0.1 0.24 12.0 0.1 1.6 1 1 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature TFIIB PF00382.14 AFZ79071.1 - 2.5e-12 46.4 0.9 1.1e-09 37.9 0.0 2.6 2 1 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AFZ79071.1 - 1.5e-09 37.0 0.5 1.5e-09 37.0 0.4 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding HTH_Tnp_ISL3 PF13542.1 AFZ79071.1 - 0.066 12.3 0.1 0.23 10.6 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 AAA_18 PF13238.1 AFZ79072.1 - 9.6e-24 84.1 0.4 1.4e-23 83.6 0.3 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AFZ79072.1 - 3.8e-14 53.5 0.3 8.3e-14 52.4 0.1 1.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 AFZ79072.1 - 2e-07 30.9 0.0 0.00013 21.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain ADK PF00406.17 AFZ79072.1 - 1.2e-05 25.1 0.1 0.00091 19.1 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_16 PF13191.1 AFZ79072.1 - 1.4e-05 25.1 0.4 6.1e-05 23.0 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 AFZ79072.1 - 2.2e-05 24.6 0.9 4.9e-05 23.5 0.6 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AFZ79072.1 - 2.3e-05 24.5 0.6 6.6e-05 23.0 0.4 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 AFZ79072.1 - 0.00024 20.7 0.0 0.00056 19.5 0.0 1.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 AFZ79072.1 - 0.00036 20.2 0.1 0.00063 19.4 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 AFZ79072.1 - 0.00039 20.1 0.0 0.0013 18.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 AFZ79072.1 - 0.00048 19.0 2.9 0.0016 17.3 2.0 1.8 1 1 0 1 1 1 1 NB-ARC domain AAA_10 PF12846.2 AFZ79072.1 - 0.00068 19.1 1.5 0.0019 17.6 0.0 1.9 1 1 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 AFZ79072.1 - 0.00077 19.7 0.6 0.0018 18.5 0.4 1.6 1 1 0 1 1 1 1 ABC transporter ATP_bind_1 PF03029.12 AFZ79072.1 - 0.0011 18.5 1.5 0.069 12.6 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Miro PF08477.8 AFZ79072.1 - 0.0012 19.3 0.3 0.0049 17.3 0.0 1.9 1 1 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 AFZ79072.1 - 0.0012 18.8 0.0 0.0062 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 AFZ79072.1 - 0.0016 17.4 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) MobB PF03205.9 AFZ79072.1 - 0.0017 18.0 0.1 0.0034 17.0 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 AFZ79072.1 - 0.0019 18.1 0.7 0.0042 17.0 0.5 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 AFZ79072.1 - 0.0022 17.8 3.4 0.033 14.1 2.4 2.1 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 AFZ79072.1 - 0.0027 17.4 0.7 0.0058 16.3 0.5 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_24 PF13479.1 AFZ79072.1 - 0.0029 17.1 0.1 0.0069 15.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 AFZ79072.1 - 0.0032 17.3 0.0 2.2 8.1 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase NTPase_1 PF03266.10 AFZ79072.1 - 0.0035 17.0 0.8 0.0056 16.4 0.1 1.7 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.17 AFZ79072.1 - 0.0083 16.2 0.1 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.12 AFZ79072.1 - 0.0083 15.9 0.7 0.099 12.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 AFZ79072.1 - 0.0086 15.5 0.1 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_32 PF13654.1 AFZ79072.1 - 0.011 14.4 0.7 0.046 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 AFZ79072.1 - 0.013 14.9 0.1 0.042 13.2 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Thymidylate_kin PF02223.12 AFZ79072.1 - 0.014 14.8 1.3 2.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase DUF258 PF03193.11 AFZ79072.1 - 0.014 14.6 0.1 0.026 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 AFZ79072.1 - 0.014 14.5 0.1 0.052 12.6 0.0 1.9 2 1 0 2 2 2 0 Zeta toxin dNK PF01712.14 AFZ79072.1 - 0.02 14.7 0.7 0.043 13.7 0.5 1.6 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_29 PF13555.1 AFZ79072.1 - 0.021 14.3 0.1 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 AFZ79072.1 - 0.024 13.7 0.2 0.076 12.1 0.0 1.9 2 1 0 2 2 2 0 KaiC KTI12 PF08433.5 AFZ79072.1 - 0.026 13.7 0.2 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 UvrD-helicase PF00580.16 AFZ79072.1 - 0.03 13.6 0.8 0.19 10.9 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Mg_chelatase PF01078.16 AFZ79072.1 - 0.031 13.4 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 AFZ79072.1 - 0.031 13.9 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.20 AFZ79072.1 - 0.038 13.4 0.0 0.038 13.4 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MCM PF00493.18 AFZ79072.1 - 0.05 12.4 1.3 0.056 12.2 0.0 1.6 2 0 0 2 2 2 0 MCM2/3/5 family cobW PF02492.14 AFZ79072.1 - 0.069 12.5 0.4 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.21 AFZ79072.1 - 0.09 12.2 0.0 0.21 11.0 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain T2SE PF00437.15 AFZ79072.1 - 0.11 11.4 0.8 0.14 11.0 0.1 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.1 AFZ79072.1 - 0.15 11.4 0.5 0.37 10.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 AFZ79072.1 - 0.17 10.6 0.3 0.39 9.4 0.0 1.6 2 0 0 2 2 2 0 ArgK protein AIG1 PF04548.11 AFZ79072.1 - 0.62 9.1 4.6 5.3 6.0 0.1 2.2 1 1 1 2 2 2 0 AIG1 family Nol1_Nop2_Fmu PF01189.12 AFZ79073.1 - 4.9e-32 111.4 0.0 6.5e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 AFZ79073.1 - 4.4e-12 45.8 0.0 7.3e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AFZ79073.1 - 8.4e-09 35.0 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 AFZ79073.1 - 7.8e-07 28.4 0.0 1.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AFZ79073.1 - 1.1e-06 28.6 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AFZ79073.1 - 0.0053 17.2 0.0 2.9 8.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 AFZ79073.1 - 0.0068 16.7 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AFZ79073.1 - 0.015 15.7 0.0 5.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 AFZ79073.1 - 0.056 13.4 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 AFZ79073.1 - 0.079 13.5 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 AFZ79073.1 - 0.12 11.8 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF485 PF04341.7 AFZ79074.1 - 0.0079 15.8 3.7 0.036 13.7 0.5 2.3 2 1 1 3 3 3 1 Protein of unknown function, DUF485 PilN PF05137.8 AFZ79074.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) RNA_POL_M_15KD PF02150.11 AFZ79075.1 - 3.3e-07 29.8 4.4 9.7e-07 28.3 1.8 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 AFZ79075.1 - 1.7e-05 24.3 1.1 1.7e-05 24.3 0.7 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.2 AFZ79075.1 - 0.031 14.0 1.9 0.031 14.0 1.3 2.3 2 1 1 3 3 3 0 Double zinc ribbon zf-B_box PF00643.19 AFZ79075.1 - 0.066 13.1 2.0 0.066 13.1 1.4 2.3 2 0 0 2 2 2 0 B-box zinc finger GFA PF04828.9 AFZ79075.1 - 0.54 10.2 8.2 1.7 8.6 0.2 3.2 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme IBR PF01485.16 AFZ79075.1 - 0.68 9.8 9.9 8.7 6.3 2.9 3.1 1 1 1 2 2 2 0 IBR domain DUF2387 PF09526.5 AFZ79075.1 - 0.83 9.6 5.5 6.2 6.8 0.4 2.8 2 1 1 3 3 3 0 Probable metal-binding protein (DUF2387) OrfB_Zn_ribbon PF07282.6 AFZ79075.1 - 1.3 8.7 9.4 0.39 10.3 0.9 2.7 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Nudix_N_2 PF14803.1 AFZ79075.1 - 2.2 8.0 5.6 3.1 7.5 2.0 2.5 2 1 0 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.1 AFZ79075.1 - 2.3 7.5 7.7 3.4 6.9 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Rpr2 PF04032.11 AFZ79075.1 - 3.9 7.4 6.0 12 5.8 1.6 2.8 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_ribbon_recom PF13408.1 AFZ79075.1 - 4.3 7.6 9.6 0.15 12.3 1.4 2.3 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Evr1_Alr PF04777.8 AFZ79076.1 - 3.4e-22 78.1 0.0 4.7e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Spore_III_AB PF09548.5 AFZ79078.1 - 0.033 13.9 1.4 0.056 13.1 1.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NPV_P10 PF05531.7 AFZ79078.1 - 0.065 13.4 4.9 0.44 10.8 1.8 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF745 PF05335.8 AFZ79078.1 - 0.28 10.6 1.2 0.45 10.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) EMP24_GP25L PF01105.19 AFZ79078.1 - 0.56 9.8 3.3 1.8 8.2 2.3 1.8 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TMF_DNA_bd PF12329.3 AFZ79078.1 - 0.87 9.4 7.2 0.29 10.9 0.2 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 AFZ79078.1 - 1 9.4 5.8 2.1 8.4 4.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 AFZ79078.1 - 1.2 8.9 5.3 1.9 8.2 3.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.7 AFZ79078.1 - 3.1 8.2 4.9 25 5.3 0.5 2.6 3 0 0 3 3 3 0 SlyX G10 PF01125.12 AFZ79079.1 - 7.4e-62 207.2 1.5 8.2e-62 207.0 1.1 1.0 1 0 0 1 1 1 1 G10 protein zf-CCCH PF00642.19 AFZ79080.1 - 1.1e-06 28.1 3.0 1.1e-06 28.1 2.0 5.0 5 1 0 5 5 5 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AFZ79080.1 - 0.013 15.4 10.5 1.4 8.9 0.5 4.7 4 2 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type Peptidase_M16_C PF05193.16 AFZ79081.1 - 5.9e-32 110.8 0.0 4.1e-30 104.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AFZ79081.1 - 2e-28 99.0 0.0 4.3e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Nup84_Nup100 PF04121.8 AFZ79083.1 - 0.1 10.2 0.0 0.11 10.1 0.0 1.0 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 DnaJ-X PF14308.1 AFZ79084.1 - 4.1e-50 169.9 2.9 8.9e-50 168.8 2.0 1.5 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 AFZ79084.1 - 7.9e-25 86.3 1.4 1.7e-24 85.2 0.7 1.8 2 0 0 2 2 2 1 DnaJ domain ATG_C PF09333.6 AFZ79084.1 - 7.1e-06 26.0 0.0 2.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain Cut12 PF11500.3 AFZ79084.1 - 0.017 14.7 0.7 0.017 14.7 0.5 2.0 3 0 0 3 3 3 0 Spindle pole body formation-associated protein Ribosomal_S14 PF00253.16 AFZ79085.1 - 6.6e-18 63.8 3.6 7.6e-18 63.6 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-met2 PF12907.2 AFZ79085.1 - 3.4 7.7 6.2 18 5.4 0.1 2.9 3 0 0 3 3 3 0 Zinc-binding CAP PF00188.21 AFZ79086.1 - 1.5e-19 70.7 0.1 1.9e-19 70.3 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family AP2 PF00847.15 AFZ79089.1 - 5.1e-08 32.9 0.8 5.1e-08 32.9 0.6 2.4 2 1 1 3 3 3 1 AP2 domain WD40 PF00400.27 AFZ79090.1 - 8.4e-12 44.4 5.7 9.8e-07 28.4 0.1 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AFZ79090.1 - 0.014 14.1 0.6 0.026 13.3 0.1 1.5 2 0 0 2 2 2 0 Nup133 N terminal like Coatomer_WDAD PF04053.9 AFZ79090.1 - 0.075 11.8 3.0 0.088 11.5 1.7 1.3 1 1 0 1 1 1 0 Coatomer WD associated region SNARE PF05739.14 AFZ79091.1 - 4.7e-11 42.2 1.9 4.7e-11 42.2 1.3 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 AFZ79091.1 - 2.3e-07 30.9 3.2 2.8e-07 30.6 0.3 2.2 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 AFZ79091.1 - 9.1e-06 25.6 2.7 9.1e-06 25.6 1.9 1.9 2 0 0 2 2 2 1 Syntaxin-like protein NinE PF05322.6 AFZ79091.1 - 0.025 14.3 1.1 0.055 13.2 0.7 1.6 1 0 0 1 1 1 0 NINE Protein MCM_N PF14551.1 AFZ79091.1 - 0.034 14.6 4.2 0.36 11.3 2.9 2.2 1 1 0 1 1 1 0 MCM N-terminal domain Tetrabrachion PF11401.3 AFZ79091.1 - 0.077 12.7 0.2 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Tetrabrachion Josephin PF02099.12 AFZ79092.1 - 8.7e-22 77.4 0.1 1.2e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Josephin zf-FPG_IleRS PF06827.9 AFZ79092.1 - 0.041 13.5 0.2 0.15 11.7 0.1 2.0 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS IBN_N PF03810.14 AFZ79093.1 - 5.2e-10 39.1 0.0 3.5e-09 36.4 0.0 2.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain CFIA_Pcf11 PF11526.3 AFZ79093.1 - 0.46 10.6 4.2 0.11 12.6 0.3 1.9 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 DUF3464 PF11947.3 AFZ79094.1 - 1 8.8 8.8 0.57 9.6 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) CHCH PF06747.8 AFZ79096.1 - 0.0047 16.8 3.1 0.61 10.0 2.3 2.2 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 AFZ79096.1 - 0.33 10.7 4.0 1.6 8.5 0.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like GCV_H PF01597.14 AFZ79097.1 - 2.2e-06 27.3 0.0 6.3e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Glycine cleavage H-protein CaKB PF03185.10 AFZ79097.1 - 0.026 13.9 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Ribosomal_L37e PF01907.14 AFZ79098.1 - 2.1e-25 88.2 6.9 3.8e-25 87.4 4.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 AFZ79098.1 - 0.0031 17.3 2.8 0.0059 16.3 1.9 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_6 PF14599.1 AFZ79098.1 - 0.034 13.9 1.3 0.056 13.2 0.5 1.7 2 0 0 2 2 2 0 Zinc-ribbon zf-RanBP PF00641.13 AFZ79098.1 - 0.05 12.7 2.3 1.4 8.0 0.1 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF1258 PF06869.7 AFZ79098.1 - 0.083 11.9 0.6 0.1 11.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) zf-RING_5 PF14634.1 AFZ79098.1 - 0.15 11.8 5.6 0.11 12.2 2.5 1.8 2 0 0 2 2 2 0 zinc-RING finger domain HypA PF01155.14 AFZ79098.1 - 0.16 11.6 0.3 0.26 11.0 0.2 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Auto_anti-p27 PF06677.7 AFZ79098.1 - 0.25 11.1 2.7 0.55 10.0 1.8 1.7 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C3HC4_3 PF13920.1 AFZ79098.1 - 0.26 10.9 2.8 0.65 9.7 1.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GATA PF00320.22 AFZ79098.1 - 0.4 10.0 4.3 1.3 8.3 1.0 2.6 2 0 0 2 2 2 0 GATA zinc finger zf-C3HC4_2 PF13923.1 AFZ79098.1 - 0.74 9.8 4.6 0.49 10.4 1.7 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AFZ79098.1 - 9.6 5.9 7.3 4.9 6.8 3.4 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DnaG_DnaB_bind PF08278.6 AFZ79099.1 - 0.0048 17.1 0.2 0.67 10.1 0.1 2.6 1 1 1 2 2 2 2 DNA primase DnaG DnaB-binding CRC_subunit PF08624.5 AFZ79099.1 - 0.061 13.2 0.0 3.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit RNA_pol_N PF01194.12 AFZ79100.1 - 8.4e-32 109.0 0.5 9.9e-32 108.7 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 AFZ79100.1 - 0.13 12.3 0.7 0.3 11.2 0.5 1.6 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) SynMuv_product PF06047.6 AFZ79101.1 - 2.4e-44 149.3 5.7 5.6e-44 148.1 3.9 1.6 1 0 0 1 1 1 1 Ras-induced vulval development antagonist SPATA24 PF15175.1 AFZ79101.1 - 0.0053 16.4 2.6 0.0097 15.6 1.8 1.4 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 LMBR1 PF04791.11 AFZ79101.1 - 2.4 6.6 5.6 0.23 10.0 0.8 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF2683 PF10884.3 AFZ79103.1 - 0.015 15.2 1.6 0.02 14.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) Kdo PF06293.9 AFZ79104.1 - 1.7e-12 46.8 0.0 4.8e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 AFZ79104.1 - 1.8e-12 46.9 0.1 2.3e-12 46.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 AFZ79104.1 - 9e-10 38.2 0.0 1.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 AFZ79104.1 - 2.2e-08 34.1 0.0 0.00013 21.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 AFZ79104.1 - 1.8e-07 30.6 0.1 2e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.12 AFZ79104.1 - 2e-07 30.3 0.1 2.6e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.15 AFZ79104.1 - 8.9e-06 25.0 0.0 9.9e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 AFZ79104.1 - 8.9e-05 22.1 0.1 0.047 13.2 0.0 2.1 1 1 1 2 2 2 2 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 AFZ79104.1 - 0.027 13.3 0.6 0.048 12.4 0.2 1.5 1 1 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.1 AFZ79104.1 - 0.036 13.0 0.0 0.062 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Fructosamin_kin PF03881.9 AFZ79104.1 - 0.04 12.8 0.0 4.1 6.2 0.0 2.0 1 1 1 2 2 2 0 Fructosamine kinase DNA_pol3_alpha PF07733.7 AFZ79104.1 - 0.11 10.9 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit SCO1-SenC PF02630.9 AFZ79105.1 - 3.4e-52 176.5 0.3 4.4e-52 176.2 0.2 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 AFZ79105.1 - 4.2e-07 29.6 0.0 7.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 AFZ79105.1 - 7.6e-05 22.7 0.1 0.00018 21.5 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 AFZ79105.1 - 0.0019 17.7 0.1 0.016 14.7 0.0 2.2 2 1 0 2 2 2 1 Redoxin Mu-like_Com PF10122.4 AFZ79105.1 - 0.047 12.7 0.2 0.08 12.0 0.2 1.3 1 0 0 1 1 1 0 Mu-like prophage protein Com Thioredoxin_2 PF13098.1 AFZ79105.1 - 0.18 11.9 0.8 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain HSP70 PF00012.15 AFZ79106.1 - 5.4e-78 262.4 0.0 1e-77 261.4 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AFZ79106.1 - 1.3 7.5 3.1 9.1 4.7 0.0 2.8 2 1 0 2 2 2 0 MreB/Mbl protein HSP90 PF00183.13 AFZ79107.1 - 2.7e-257 854.4 34.9 3.6e-257 853.9 24.2 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 AFZ79107.1 - 1.6e-11 44.0 0.3 1.6e-11 44.0 0.2 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AFZ79107.1 - 9.1e-11 41.4 0.0 1.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SF3a60_bindingd PF12108.3 AFZ79107.1 - 0.17 11.4 6.9 3.2 7.3 1.4 3.0 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain DDHD PF02862.12 AFZ79107.1 - 0.45 10.2 6.7 1.1 8.9 4.7 1.6 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 AFZ79107.1 - 1.1 9.2 7.1 2.9 7.7 4.9 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family Arf PF00025.16 AFZ79108.1 - 8e-76 253.1 0.5 9.5e-76 252.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AFZ79108.1 - 2.2e-14 53.0 0.0 2.8e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AFZ79108.1 - 2.8e-13 49.5 0.1 3.1e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 AFZ79108.1 - 2.9e-12 45.9 1.6 4.5e-08 32.2 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AFZ79108.1 - 3.6e-10 39.3 0.0 4.5e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AFZ79108.1 - 1.8e-09 38.1 0.0 2.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AFZ79108.1 - 1.1e-05 25.3 0.1 1.6e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 AFZ79108.1 - 0.0025 16.9 0.2 0.0037 16.3 0.1 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 AFZ79108.1 - 0.0077 16.1 0.3 0.029 14.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 AFZ79108.1 - 0.075 12.6 0.2 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Paf67 PF10255.4 AFZ79110.1 - 2e-138 461.6 15.6 2.8e-138 461.1 10.8 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 NOG1 PF06858.9 AFZ79111.1 - 1e-25 89.3 0.2 2.3e-25 88.2 0.1 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 AFZ79111.1 - 4.7e-25 87.0 0.4 9.8e-25 86.0 0.2 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 AFZ79111.1 - 1.4e-16 60.4 0.0 3.8e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AFZ79111.1 - 1.5e-11 43.8 0.0 3.8e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 AFZ79111.1 - 0.0024 18.3 0.0 0.0089 16.5 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein AAA_18 PF13238.1 AFZ79111.1 - 0.029 14.6 0.2 0.87 9.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.15 AFZ79111.1 - 0.033 12.9 0.4 0.18 10.4 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.18 AFZ79111.1 - 0.053 13.3 0.5 10 5.8 0.0 2.7 2 1 1 3 3 3 0 Dynamin family AIG1 PF04548.11 AFZ79111.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 AIG1 family MFS_2 PF13347.1 AFZ79111.1 - 0.3 9.4 0.0 0.39 9.0 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein LRR_4 PF12799.2 AFZ79112.1 - 8.2e-11 41.2 14.2 0.0036 16.8 0.1 5.1 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AFZ79112.1 - 2.6e-05 23.8 17.5 0.0028 17.3 1.8 5.4 4 2 3 7 7 7 4 Leucine rich repeat LRR_1 PF00560.28 AFZ79112.1 - 0.00033 20.2 17.4 8.4 6.8 0.3 7.9 5 2 2 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.1 AFZ79112.1 - 0.0016 18.0 2.6 0.072 12.6 0.2 2.6 1 1 0 2 2 2 1 Leucine-rich repeat OSCP PF00213.13 AFZ79112.1 - 0.057 13.2 0.1 0.21 11.4 0.1 1.8 1 1 0 1 1 1 0 ATP synthase delta (OSCP) subunit LRR_6 PF13516.1 AFZ79112.1 - 0.095 12.8 18.6 3.4 8.0 0.3 7.3 6 1 1 7 7 7 0 Leucine Rich repeat LRR_7 PF13504.1 AFZ79112.1 - 3.1 8.4 11.6 18 6.0 0.1 6.4 7 0 0 7 7 7 0 Leucine rich repeat TMF_TATA_bd PF12325.3 AFZ79113.1 - 0.0019 17.9 3.0 0.0019 17.9 2.1 3.7 3 1 0 3 3 3 2 TATA element modulatory factor 1 TATA binding DUF4337 PF14235.1 AFZ79113.1 - 0.71 9.6 7.6 0.56 10.0 0.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4337) DUF4140 PF13600.1 AFZ79113.1 - 5.2 7.5 8.3 0.9 10.0 0.9 3.1 2 2 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) GNAT_acetyltr_2 PF13718.1 AFZ79114.1 - 1.1e-67 227.2 0.0 2e-67 226.3 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 AFZ79114.1 - 9.6e-50 168.6 0.0 2.3e-49 167.4 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 AFZ79114.1 - 7.9e-34 115.2 0.0 2.4e-33 113.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 AFZ79114.1 - 2e-18 66.3 0.1 7e-18 64.5 0.0 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 AFZ79114.1 - 0.017 15.2 0.0 0.067 13.3 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1975 PF09318.5 AFZ79114.1 - 0.041 13.4 0.1 0.099 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1975) RRM_DME PF15628.1 AFZ79115.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 RRM in Demeter ATP-synt_DE_N PF02823.11 AFZ79116.1 - 9.1e-17 60.6 0.0 1.2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Glyco_transf_10 PF00852.14 AFZ79118.1 - 0.063 11.8 0.0 0.24 9.9 0.0 1.7 1 1 1 2 2 2 0 Glycosyltransferase family 10 (fucosyltransferase) DUF1398 PF07166.6 AFZ79118.1 - 0.12 12.2 3.8 0.63 9.9 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1398) Ion_trans_2 PF07885.11 AFZ79119.1 - 6.3e-09 35.4 6.9 6.3e-09 35.4 4.8 2.7 2 1 0 2 2 2 1 Ion channel BK_channel_a PF03493.13 AFZ79119.1 - 1.4e-06 28.1 1.1 6.4e-05 22.8 0.3 3.0 2 1 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit M16C_assoc PF08367.6 AFZ79121.1 - 1.3e-34 119.2 8.3 5.7e-34 117.0 5.7 2.1 1 1 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 AFZ79121.1 - 2.7e-19 69.5 0.0 9.6e-12 44.9 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AFZ79121.1 - 8.4e-10 38.5 0.0 1.4e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Abhydrolase_6 PF12697.2 AFZ79122.1 - 1.8e-16 60.7 0.0 3e-16 59.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ79122.1 - 3.1e-10 39.9 0.0 5.1e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 AFZ79122.1 - 0.0023 17.5 0.0 0.0064 16.1 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 AFZ79122.1 - 0.0034 16.9 0.3 0.4 10.1 0.0 2.6 2 1 1 3 3 3 1 alpha/beta hydrolase fold BAAT_C PF08840.6 AFZ79122.1 - 0.024 14.3 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Smr PF01713.16 AFZ79122.1 - 0.027 14.6 0.2 0.2 11.8 0.1 2.2 2 0 0 2 2 2 0 Smr domain Thioesterase PF00975.15 AFZ79122.1 - 0.028 14.6 0.0 0.077 13.2 0.0 1.8 1 1 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.3 AFZ79122.1 - 0.031 14.1 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase PAF-AH_p_II PF03403.8 AFZ79122.1 - 0.048 11.9 0.0 0.18 10.0 0.0 1.9 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II zf-MIZ PF02891.15 AFZ79123.1 - 3.6e-19 68.0 1.0 3.6e-19 68.0 0.7 2.0 2 1 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 AFZ79123.1 - 0.00046 19.6 1.4 0.0017 17.8 1.0 2.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PINIT PF14324.1 AFZ79123.1 - 0.0083 16.2 0.5 0.022 14.8 0.1 1.9 2 0 0 2 2 2 1 PINIT domain PHD PF00628.24 AFZ79123.1 - 0.012 15.3 16.7 0.16 11.6 5.9 2.5 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 AFZ79123.1 - 0.093 12.6 3.7 0.29 11.0 2.6 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger DUF2296 PF10058.4 AFZ79123.1 - 2 8.2 6.8 2.2 8.1 0.1 2.7 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) DUF106 PF01956.11 AFZ79126.1 - 1.4e-13 50.7 1.7 1.4e-13 50.7 1.2 1.5 2 0 0 2 2 2 1 Integral membrane protein DUF106 RRM_1 PF00076.17 AFZ79127.1 - 6.9e-18 64.0 0.0 1.2e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ79127.1 - 5.6e-11 42.2 0.0 9.7e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF900 PF05990.7 AFZ79129.1 - 1.7e-12 47.1 0.0 3e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF900) IGPS PF00218.16 AFZ79131.1 - 3.9e-26 91.6 0.3 7.4e-26 90.7 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase DHO_dh PF01180.16 AFZ79131.1 - 0.013 14.4 0.0 0.029 13.3 0.0 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Leo1 PF04004.8 AFZ79131.1 - 0.41 10.3 3.6 0.15 11.7 0.3 1.8 2 0 0 2 2 2 0 Leo1-like protein WD40 PF00400.27 AFZ79132.1 - 1e-17 63.2 4.3 2e-06 27.4 0.1 5.0 4 1 0 4 4 4 4 WD domain, G-beta repeat PUL PF08324.6 AFZ79132.1 - 4.7e-11 42.0 7.4 4.7e-11 42.0 5.1 1.8 2 0 0 2 2 2 1 PUL domain Nup160 PF11715.3 AFZ79132.1 - 0.00011 20.4 0.0 0.0002 19.6 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AFZ79132.1 - 0.0025 16.6 0.9 0.0079 14.9 0.1 2.1 2 0 0 2 2 2 1 Nup133 N terminal like CutA1 PF03091.10 AFZ79132.1 - 0.021 14.4 0.2 0.049 13.2 0.1 1.6 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Ribosomal_L9_N PF01281.14 AFZ79133.1 - 4.7e-14 51.3 0.0 7.7e-14 50.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DUF2439 PF10382.4 AFZ79135.1 - 2.7e-08 33.8 0.6 6.4e-08 32.6 0.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2439) DNA_pol_E_B PF04042.11 AFZ79136.1 - 6.8e-23 81.0 0.1 1.2e-22 80.2 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF2252 PF10009.4 AFZ79137.1 - 0.12 11.2 0.4 0.19 10.6 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) NACHT PF05729.7 AFZ79138.1 - 0.00073 19.2 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 AFZ79138.1 - 0.0028 17.5 0.3 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AFZ79138.1 - 0.0044 16.7 0.0 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 AFZ79138.1 - 0.0069 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.1 AFZ79138.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Bac_DnaA PF00308.13 AFZ79138.1 - 0.017 14.7 0.0 0.045 13.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein DUF2075 PF09848.4 AFZ79138.1 - 0.021 13.8 0.0 0.042 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 AFZ79138.1 - 0.028 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 AFZ79138.1 - 0.033 13.6 0.1 0.053 12.9 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 AFZ79138.1 - 0.043 13.2 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AFZ79138.1 - 0.075 12.7 1.5 0.1 12.2 0.0 1.9 3 0 0 3 3 3 0 Archaeal ATPase CTDII PF01556.13 AFZ79139.1 - 3e-18 65.4 6.5 4.1e-09 36.2 0.1 4.0 3 2 0 3 3 3 3 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AFZ79139.1 - 1.8e-10 40.6 14.9 3.1e-10 39.9 10.3 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 AFZ79139.1 - 2.6e-06 27.0 1.9 1.8e-05 24.3 1.3 2.2 1 1 0 1 1 1 1 DnaJ domain DUF2318 PF10080.4 AFZ79139.1 - 0.033 13.9 5.1 2 8.2 0.2 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) TPR_11 PF13414.1 AFZ79140.1 - 2.6e-13 49.3 0.9 2.6e-07 30.1 0.0 2.0 1 1 1 2 2 2 2 TPR repeat Fis1_TPR_C PF14853.1 AFZ79140.1 - 4.6e-10 39.2 1.2 7.8e-10 38.4 0.9 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.1 AFZ79140.1 - 3.9e-06 27.3 0.4 0.013 16.1 0.1 2.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 AFZ79140.1 - 4.3e-05 23.6 0.0 0.0028 18.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 AFZ79140.1 - 5.7e-05 22.7 1.1 0.00022 20.9 0.1 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 AFZ79140.1 - 0.00033 20.7 0.8 0.00071 19.6 0.5 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 AFZ79140.1 - 0.00066 19.6 0.2 0.2 11.9 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 AFZ79140.1 - 0.0011 18.4 0.2 0.0022 17.5 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 AFZ79140.1 - 0.0022 18.3 0.1 0.004 17.4 0.0 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat SRR1 PF07985.7 AFZ79140.1 - 0.014 15.3 0.1 0.029 14.2 0.0 1.6 1 1 0 1 1 1 0 SRR1 Fis1_TPR_N PF14852.1 AFZ79140.1 - 0.029 13.6 0.0 0.065 12.5 0.0 1.6 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat TPR_8 PF13181.1 AFZ79140.1 - 0.034 13.9 0.1 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 AFZ79140.1 - 0.05 14.2 0.0 0.17 12.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L39 PF00832.15 AFZ79141.1 - 3.2e-22 77.7 11.1 3.5e-22 77.5 7.7 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein DUF747 PF05346.6 AFZ79144.1 - 5e-26 91.5 2.5 5.6e-26 91.3 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF747 PF05346.6 AFZ79145.1 - 6.6e-70 235.7 6.1 9.7e-70 235.2 4.2 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DEAD PF00270.24 AFZ79146.1 - 2e-33 115.2 0.1 3.2e-33 114.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ79146.1 - 1.1e-19 70.0 0.2 8.2e-19 67.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AFZ79146.1 - 0.00012 21.0 1.5 0.00027 19.8 0.2 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 AFZ79146.1 - 0.00079 19.3 1.0 0.0071 16.1 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 AFZ79146.1 - 0.012 14.9 0.0 0.078 12.2 0.0 2.2 1 1 0 1 1 1 0 SecA DEAD-like domain Helicase_C_2 PF13307.1 AFZ79146.1 - 0.06 13.3 0.1 5.8 6.8 0.0 3.2 1 1 2 3 3 3 0 Helicase C-terminal domain TnpW PF14202.1 AFZ79146.1 - 0.08 12.5 0.2 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpW AAA_22 PF13401.1 AFZ79146.1 - 0.26 11.4 1.7 1.5 8.9 0.3 2.5 2 1 0 2 2 2 0 AAA domain Exo_endo_phos PF03372.18 AFZ79147.1 - 2.9e-10 40.4 0.1 4.3e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UQ_con PF00179.21 AFZ79148.1 - 1.8e-44 150.5 0.0 2e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AFZ79148.1 - 7.5e-06 25.7 0.0 9.4e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AFZ79148.1 - 0.00069 19.4 0.0 0.00085 19.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain Cpn60_TCP1 PF00118.19 AFZ79149.1 - 1.2e-139 466.1 7.9 1.4e-139 465.9 5.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Synaptobrevin PF00957.16 AFZ79150.1 - 3.5e-19 68.2 0.3 5.9e-19 67.4 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 AFZ79150.1 - 5e-18 64.4 0.6 8.2e-18 63.7 0.4 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain IPP-2 PF04979.9 AFZ79151.1 - 2.7e-08 34.1 11.3 0.00065 19.9 0.3 2.1 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Phage_portal PF04860.7 AFZ79151.1 - 0.023 13.3 0.1 0.027 13.1 0.1 1.1 1 0 0 1 1 1 0 Phage portal protein HPPK PF01288.15 AFZ79151.1 - 0.027 14.1 0.1 0.032 13.9 0.1 1.2 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF2340 PF10209.4 AFZ79151.1 - 0.063 13.4 0.8 0.088 12.9 0.2 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2340) DUF3098 PF11297.3 AFZ79152.1 - 0.16 11.6 0.1 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) HA2 PF04408.18 AFZ79153.1 - 6e-22 77.5 0.1 1.5e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AFZ79153.1 - 1.5e-18 66.7 0.2 7.4e-18 64.4 0.1 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AFZ79153.1 - 1.4e-12 47.2 0.0 1.3e-11 44.1 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 AFZ79153.1 - 3.5e-12 46.1 0.6 1.1e-11 44.5 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AFZ79153.1 - 1.4e-06 28.4 0.0 4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 AFZ79153.1 - 4.1e-05 23.3 0.0 9.8e-05 22.1 0.0 1.7 2 0 0 2 2 1 1 Flavivirus DEAD domain ABC_tran PF00005.22 AFZ79153.1 - 4.1e-05 23.8 0.2 0.00067 19.9 0.1 2.7 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 AFZ79153.1 - 0.00035 20.0 0.0 0.00087 18.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ResIII PF04851.10 AFZ79153.1 - 0.0015 18.3 0.8 0.021 14.6 0.1 2.6 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 AFZ79153.1 - 0.0017 17.3 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF258 PF03193.11 AFZ79153.1 - 0.0023 17.1 0.0 0.0054 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 AFZ79153.1 - 0.0025 17.5 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_23 PF13476.1 AFZ79153.1 - 0.0035 17.6 4.7 0.018 15.3 3.3 2.2 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 AFZ79153.1 - 0.0043 16.7 0.0 0.023 14.3 0.0 2.3 2 0 0 2 2 2 1 Helicase NB-ARC PF00931.17 AFZ79153.1 - 0.011 14.5 0.2 0.022 13.6 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 AFZ79153.1 - 0.012 15.5 0.4 0.1 12.4 0.2 2.4 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 AFZ79153.1 - 0.029 13.3 0.0 0.064 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 AFZ79153.1 - 0.03 13.7 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain PhoH PF02562.11 AFZ79153.1 - 0.04 13.1 0.1 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Miro PF08477.8 AFZ79153.1 - 0.056 13.9 0.6 0.18 12.2 0.0 2.1 2 0 0 2 2 1 0 Miro-like protein Arch_ATPase PF01637.13 AFZ79153.1 - 0.075 12.7 3.8 0.042 13.5 0.5 2.0 2 0 0 2 2 2 0 Archaeal ATPase cobW PF02492.14 AFZ79153.1 - 0.077 12.4 0.2 0.6 9.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 AFZ79153.1 - 0.086 12.4 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 AFZ79153.1 - 0.09 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 AFZ79153.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.12 AFZ79153.1 - 0.11 12.3 1.2 0.61 9.8 0.0 2.5 3 0 0 3 3 2 0 Domain of unknown function DUF87 AAA_16 PF13191.1 AFZ79153.1 - 0.13 12.2 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.14 AFZ79153.1 - 0.14 11.3 0.1 0.44 9.7 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 AFZ79153.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 AFZ79154.1 - 3.8e-13 48.8 22.0 3.8e-13 48.8 15.3 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AFZ79154.1 - 6.7e-11 41.4 19.1 6.7e-11 41.4 13.2 1.6 1 1 1 2 2 2 1 Sugar (and other) transporter Sigma_reg_N PF13800.1 AFZ79154.1 - 3.7 7.6 5.6 6.5 6.8 0.4 3.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF1754 PF08555.5 AFZ79155.1 - 2.9 8.5 12.5 12 6.6 7.9 2.2 1 1 1 2 2 2 0 Eukaryotic family of unknown function (DUF1754) L51_S25_CI-B8 PF05047.11 AFZ79157.1 - 8.1e-06 25.4 0.0 1.9e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ribosomal_S17 PF00366.15 AFZ79158.1 - 3.4e-28 97.4 0.7 6e-28 96.6 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 COX4 PF02936.9 AFZ79163.1 - 0.026 14.2 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV PCI_Csn8 PF10075.4 AFZ79168.1 - 3.4e-22 78.7 0.0 5.1e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 AFZ79168.1 - 4.2e-13 49.3 0.2 5.7e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 AFZ79168.1 - 0.043 14.1 0.1 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 PCI domain Adaptin_N PF01602.15 AFZ79169.1 - 4.5e-129 431.1 12.9 5.7e-129 430.8 8.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 AFZ79169.1 - 3.8e-24 85.5 9.2 6e-24 84.8 0.3 4.1 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 AFZ79169.1 - 5.4e-12 45.8 8.0 3.4e-05 24.0 0.0 5.5 5 2 1 6 6 6 2 HEAT repeats HEAT PF02985.17 AFZ79169.1 - 9.3e-11 40.8 2.1 0.014 15.4 0.0 6.0 5 0 0 5 5 5 2 HEAT repeat B2-adapt-app_C PF09066.5 AFZ79169.1 - 8.8e-09 35.2 0.1 7.2e-08 32.2 0.0 2.4 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain Arm PF00514.18 AFZ79169.1 - 8.4e-06 25.4 0.8 0.0013 18.4 0.0 4.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 AFZ79169.1 - 0.0015 18.2 0.0 0.11 12.2 0.0 3.2 2 1 1 3 3 3 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 AFZ79169.1 - 0.0081 15.5 0.3 0.44 9.8 0.0 3.6 4 1 1 5 5 5 1 CLASP N terminal Alpha_adaptinC2 PF02883.15 AFZ79169.1 - 0.044 14.0 0.1 0.089 13.1 0.1 1.4 1 0 0 1 1 1 0 Adaptin C-terminal domain HEAT_EZ PF13513.1 AFZ79169.1 - 0.075 13.5 0.7 13 6.4 0.0 3.9 3 1 0 3 3 3 0 HEAT-like repeat Ribosomal_L7Ae PF01248.21 AFZ79170.1 - 1.9e-23 81.7 0.0 2.4e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family APP_Cu_bd PF12924.2 AFZ79170.1 - 0.034 14.6 0.1 0.06 13.8 0.0 1.6 1 1 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD JAB PF01398.16 AFZ79172.1 - 1.9e-07 30.8 0.0 2.6e-05 23.9 0.0 2.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA-synt_1 PF00133.17 AFZ79174.1 - 1.6e-208 693.6 0.1 2e-208 693.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AFZ79174.1 - 2.9e-22 79.0 0.0 6e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AFZ79174.1 - 1.2e-18 66.9 5.2 1.9e-06 26.8 1.1 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 AFZ79174.1 - 0.017 14.2 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Cpn10 PF00166.16 AFZ79175.1 - 3e-27 94.3 0.0 1.5e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit NTP_transf_2 PF01909.18 AFZ79176.1 - 7.6e-09 35.7 0.0 2e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 AFZ79176.1 - 0.0057 16.5 0.4 0.015 15.2 0.3 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase Sedlin_N PF04628.8 AFZ79177.1 - 1.2e-34 118.9 0.0 1.6e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Laminin_I PF06008.9 AFZ79178.1 - 0.0011 18.4 1.3 0.0019 17.5 0.9 1.3 1 0 0 1 1 1 1 Laminin Domain I Jnk-SapK_ap_N PF09744.4 AFZ79178.1 - 0.0012 18.8 3.0 0.0026 17.7 2.1 1.5 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 RAP PF08373.5 AFZ79180.1 - 8.9e-05 22.1 0.0 0.00032 20.4 0.0 1.9 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.10 AFZ79180.1 - 0.00052 19.6 0.5 0.61 9.8 0.0 4.0 5 1 1 6 6 6 2 FAST kinase-like protein, subdomain 1 TRAPP PF04051.11 AFZ79181.1 - 9.2e-25 86.9 0.0 1.2e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DEAD PF00270.24 AFZ79182.1 - 2e-43 147.8 0.0 4.6e-41 140.1 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ79182.1 - 2e-27 94.8 0.0 4.1e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ79182.1 - 0.0004 20.2 0.0 0.0014 18.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 AFZ79182.1 - 0.013 15.4 0.0 0.041 13.8 0.0 1.8 2 0 0 2 2 2 0 Helicase C-terminal domain SecA_DEAD PF07517.9 AFZ79182.1 - 0.02 14.2 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Ribosomal_L18e PF00828.14 AFZ79183.1 - 3.4e-33 114.7 0.5 4.1e-33 114.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Nucleoporin_FG PF13634.1 AFZ79184.1 - 4.9e-26 91.2 165.6 8.9e-08 32.3 25.8 5.0 2 2 2 4 4 4 4 Nucleoporin FG repeat region Glu-tRNAGln PF02686.10 AFZ79184.1 - 0.12 12.2 1.3 0.23 11.3 0.1 2.0 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Thymidylate_kin PF02223.12 AFZ79185.1 - 1.8e-35 122.0 0.0 2e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.1 AFZ79185.1 - 0.02 15.1 0.0 0.099 12.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain KTI12 PF08433.5 AFZ79185.1 - 0.082 12.1 0.0 0.21 10.7 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 PPK2 PF03976.9 AFZ79185.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) Pkinase PF00069.20 AFZ79186.1 - 3.3e-52 177.1 0.0 8.3e-41 139.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ79186.1 - 3.4e-25 88.6 0.0 1.2e-24 86.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Med28 PF11594.3 AFZ79186.1 - 0.0064 16.7 1.1 0.0094 16.1 0.0 1.8 2 0 0 2 2 2 1 Mediator complex subunit 28 APH PF01636.18 AFZ79186.1 - 0.053 13.2 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 AFZ79186.1 - 0.06 12.6 0.0 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL MSP7_C PF12948.2 AFZ79187.1 - 0.0031 17.7 0.8 0.89 9.8 0.0 2.5 2 0 0 2 2 2 2 MSP7-like protein C-terminal domain PTPLA PF04387.9 AFZ79188.1 - 1.9e-07 30.6 5.3 1.9e-07 30.6 3.7 2.2 2 1 0 2 2 2 2 Protein tyrosine phosphatase-like protein, PTPLA tRNA-synt_1c PF00749.16 AFZ79189.1 - 1.1e-96 323.1 0.0 1.7e-96 322.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 AFZ79189.1 - 3.3e-40 137.5 0.0 5.7e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_L14 PF00238.14 AFZ79190.1 - 2e-34 117.9 0.0 2.2e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SNARE PF05739.14 AFZ79191.1 - 6.9e-11 41.6 0.6 6.9e-11 41.6 0.4 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 AFZ79191.1 - 0.0007 19.7 10.9 0.0007 19.7 7.6 2.3 2 0 0 2 2 2 1 Syntaxin DUF2730 PF10805.3 AFZ79191.1 - 0.11 12.1 4.9 0.25 11.0 2.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Baculo_PEP_C PF04513.7 AFZ79191.1 - 0.47 10.2 15.3 1.4 8.7 4.6 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.1 AFZ79191.1 - 1.9 8.4 12.4 0.71 9.8 1.0 3.3 1 1 2 3 3 3 0 FlxA-like protein Fra10Ac1 PF09725.4 AFZ79192.1 - 1.6e-41 141.0 5.3 2.5e-41 140.4 3.7 1.3 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 FYVE PF01363.16 AFZ79192.1 - 0.087 12.7 2.4 0.19 11.6 1.7 1.6 1 0 0 1 1 1 0 FYVE zinc finger DUF3161 PF11362.3 AFZ79193.1 - 7.2e-26 89.9 0.2 1.8e-25 88.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3161) DUF1395 PF07160.7 AFZ79193.1 - 9.6e-05 21.9 1.7 0.00012 21.6 0.4 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1395) UxaC PF02614.9 AFZ79193.1 - 0.022 13.3 0.8 0.04 12.5 0.5 1.3 1 0 0 1 1 1 0 Glucuronate isomerase Rootletin PF15035.1 AFZ79193.1 - 0.12 12.3 0.9 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion LCCL PF03815.14 AFZ79194.1 - 2.3e-23 81.9 1.0 2.3e-23 81.9 0.7 2.1 2 0 0 2 2 2 1 LCCL domain F5_F8_type_C PF00754.20 AFZ79194.1 - 1.5e-16 60.4 0.7 4.6e-09 36.1 0.1 2.7 2 0 0 2 2 2 2 F5/8 type C domain COLFI PF01410.13 AFZ79194.1 - 0.0004 19.8 0.0 0.0012 18.2 0.0 1.8 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Fibrinogen_C PF00147.13 AFZ79194.1 - 0.0019 17.8 0.6 0.0053 16.3 0.0 2.0 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain Bromodomain PF00439.20 AFZ79195.1 - 1.9e-14 53.3 1.4 5e-14 51.9 0.9 1.7 1 0 0 1 1 1 1 Bromodomain Pox_MCEL PF03291.11 AFZ79196.1 - 2e-38 132.0 2.3 3.8e-38 131.1 1.6 1.4 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 AFZ79196.1 - 1.3e-11 44.2 0.1 3.4e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AFZ79196.1 - 1.1e-10 41.8 0.0 3.1e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AFZ79196.1 - 2.7e-10 40.6 0.1 1.1e-09 38.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AFZ79196.1 - 1.9e-09 37.7 0.0 7.4e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AFZ79196.1 - 5.1e-08 32.7 0.0 1.7e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AFZ79196.1 - 3e-07 31.0 0.0 7.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AFZ79196.1 - 2.3e-05 24.3 0.0 4.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain mRNA_triPase PF02940.10 AFZ79196.1 - 6.2e-05 22.8 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain DUF3577 PF12101.3 AFZ79196.1 - 0.00062 19.6 0.1 0.093 12.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3577) CMAS PF02353.15 AFZ79196.1 - 0.00084 18.4 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 AFZ79196.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.9 AFZ79196.1 - 0.062 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain TPMT PF05724.6 AFZ79196.1 - 0.089 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) EMP24_GP25L PF01105.19 AFZ79197.1 - 6.2e-22 78.1 0.0 7.5e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ThiF PF00899.16 AFZ79198.1 - 1.7e-31 108.8 0.0 1.4e-26 92.9 0.0 2.9 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 AFZ79198.1 - 9.6e-17 60.3 0.3 5.5e-16 57.8 0.2 2.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein Shikimate_DH PF01488.15 AFZ79198.1 - 2.2e-07 31.0 0.0 0.00097 19.2 0.0 2.8 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase UBA_e1_thiolCys PF10585.4 AFZ79198.1 - 0.001 18.4 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site DEAD PF00270.24 AFZ79199.1 - 6.2e-35 120.1 0.0 3.4e-34 117.7 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ79199.1 - 3.1e-27 94.2 0.0 7.4e-27 93.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ79199.1 - 0.027 14.2 0.0 0.089 12.6 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit eIF-6 PF01912.13 AFZ79200.1 - 3.6e-77 257.9 1.6 4.8e-77 257.5 1.1 1.2 1 0 0 1 1 1 1 eIF-6 family AP_endonuc_2 PF01261.19 AFZ79201.1 - 1.4e-31 109.4 0.0 2.4e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Voldacs PF03517.8 AFZ79203.1 - 4.6e-24 84.7 0.6 9.6e-24 83.7 0.4 1.5 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF1448 PF07289.6 AFZ79203.1 - 0.00078 18.4 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1448) Vps36_ESCRT-II PF11605.3 AFZ79203.1 - 0.00084 19.1 0.1 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 AFZ79203.1 - 0.069 12.6 0.2 0.15 11.6 0.2 1.7 1 1 0 1 1 1 0 GRAM domain FKBP_N PF01346.13 AFZ79204.1 - 0.034 14.1 1.4 0.034 14.1 1.0 1.6 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF445 PF04286.7 AFZ79204.1 - 0.048 13.1 5.8 0.061 12.8 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) GerPC PF10737.4 AFZ79204.1 - 0.14 11.8 5.1 0.17 11.6 3.1 1.5 1 1 0 1 1 1 0 Spore germination protein GerPC WD40 PF00400.27 AFZ79205.1 - 3e-12 45.9 24.9 0.0015 18.3 0.0 8.6 9 0 0 9 9 9 6 WD domain, G-beta repeat PD40 PF07676.7 AFZ79205.1 - 0.058 13.0 0.0 2.3 7.9 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.1 AFZ79205.1 - 0.066 12.2 0.3 64 2.3 0.0 4.2 4 1 1 5 5 5 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Atg8 PF02991.11 AFZ79206.1 - 1.2e-21 76.6 0.4 2e-21 75.9 0.3 1.3 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 AFZ79206.1 - 0.0035 17.4 0.3 0.0072 16.4 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 tRNA_Me_trans PF03054.11 AFZ79207.1 - 1.4e-96 323.1 0.0 2e-96 322.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase SufE PF02657.10 AFZ79207.1 - 2.3e-09 36.9 0.0 4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain ThiI PF02568.9 AFZ79207.1 - 9.9e-08 31.6 0.3 2.7e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.8 AFZ79207.1 - 0.0009 18.5 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 AFZ79207.1 - 0.0016 17.9 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 AFZ79207.1 - 0.0047 15.8 0.0 0.019 13.8 0.0 1.9 2 0 0 2 2 2 1 NAD synthase DUF1510 PF07423.6 AFZ79208.1 - 0.0065 15.8 0.8 0.012 14.9 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1510) Torsin PF06309.6 AFZ79208.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Torsin DUF3357 PF11837.3 AFZ79208.1 - 0.027 14.3 0.0 0.09 12.6 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) ODV-E18 PF10717.4 AFZ79208.1 - 0.079 12.4 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Peptidase_C1 PF00112.18 AFZ79209.1 - 4.5e-49 167.2 6.3 8.5e-49 166.3 4.4 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 AFZ79209.1 - 4.3e-05 23.6 0.2 0.0001 22.5 0.1 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 AFZ79209.1 - 0.00024 19.7 0.2 0.00041 19.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase C1-like family DUF1510 PF07423.6 AFZ79209.1 - 0.033 13.5 0.1 0.052 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Helicase_C_2 PF13307.1 AFZ79211.1 - 2.7e-35 121.7 0.0 5.5e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 AFZ79211.1 - 2.1e-18 66.3 9.1 2.3e-07 30.3 0.2 3.6 3 0 0 3 3 3 3 DEAD_2 DEAD PF00270.24 AFZ79211.1 - 6.8e-05 22.4 0.0 0.00047 19.6 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.1 AFZ79211.1 - 0.00011 21.8 0.0 0.0003 20.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 AFZ79211.1 - 0.0021 17.9 0.0 0.0021 17.9 0.0 2.7 2 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AFZ79211.1 - 0.0059 16.7 0.5 7.1 6.7 0.0 3.7 4 0 0 4 4 4 2 AAA domain DnaJ PF00226.26 AFZ79213.1 - 2.6e-07 30.2 0.7 4.8e-07 29.4 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain NAD_binding_9 PF13454.1 AFZ79213.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding TBPIP PF07106.8 AFZ79213.1 - 0.65 9.5 5.6 1 8.9 3.9 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FAINT PF04385.10 AFZ79214.1 - 7.2e-38 128.3 2.8 8.2e-12 44.8 0.5 4.5 4 0 0 4 4 4 4 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79214.1 - 4.1e-06 26.4 12.3 0.0056 16.1 0.3 3.6 3 1 1 4 4 4 3 Merozoite Antigen DUF2708 PF10917.3 AFZ79214.1 - 0.13 12.0 0.6 1.8 8.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2708) Crystall_3 PF08964.5 AFZ79216.1 - 0.0026 17.4 1.8 0.22 11.2 0.1 3.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Proteasom_Rpn13 PF04683.8 AFZ79217.1 - 6.1e-22 77.5 0.0 8.9e-22 76.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor UCH PF00443.24 AFZ79218.1 - 4.9e-41 140.6 3.4 4.9e-41 140.6 2.4 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AFZ79218.1 - 9.6e-27 94.1 3.7 9.6e-27 94.1 2.6 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNA_pol_Rbc25 PF08292.7 AFZ79220.1 - 3.8e-15 56.1 0.0 5.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 AFZ79220.1 - 7.8e-10 38.7 0.1 1.6e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 AFZ79220.1 - 0.012 15.7 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 S1 RNA binding domain Nop53 PF07767.6 AFZ79222.1 - 3.2e-24 85.6 20.3 2.1e-23 82.9 14.1 1.9 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) PBP1_TM PF14812.1 AFZ79222.1 - 0.38 11.0 9.5 1.2 9.4 6.6 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_S9 PF00380.14 AFZ79224.1 - 9.2e-31 106.6 0.0 1.8e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Rho_Binding PF08912.6 AFZ79225.1 - 0.019 15.2 0.6 0.056 13.7 0.1 1.9 2 0 0 2 2 2 0 Rho Binding Consortin_C PF15281.1 AFZ79225.1 - 0.023 14.1 0.1 1 8.8 0.0 2.7 3 0 0 3 3 3 0 Consortin C-terminus zf-RING_2 PF13639.1 AFZ79226.1 - 5.7e-06 26.0 11.7 5.7e-06 26.0 8.1 1.8 2 0 0 2 2 2 1 Ring finger domain zf-CCHC_2 PF13696.1 AFZ79226.1 - 2.9e-05 23.4 1.1 5.8e-05 22.4 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_4 PF15227.1 AFZ79226.1 - 4.8e-05 23.1 14.7 4.8e-05 23.1 10.2 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 AFZ79226.1 - 0.00013 21.8 14.3 0.00013 21.8 9.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AFZ79226.1 - 0.0023 17.6 14.7 0.0023 17.6 10.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AFZ79226.1 - 0.013 15.1 14.6 0.013 15.1 10.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AFZ79226.1 - 0.36 10.5 18.3 0.024 14.2 8.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 AFZ79226.1 - 0.37 10.5 4.8 0.89 9.3 3.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Metallophos PF00149.23 AFZ79229.1 - 1.4e-43 148.6 0.3 1.7e-43 148.3 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC1 PF03109.11 AFZ79230.1 - 1.4e-25 89.5 0.0 3.1e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Beta-lactamase PF00144.19 AFZ79230.1 - 3.2e-21 75.6 0.0 4.5e-18 65.3 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase mRNA_cap_enzyme PF01331.14 AFZ79231.1 - 2.5e-40 138.2 0.0 3.4e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 AFZ79231.1 - 4.6e-12 46.1 0.0 5.5e-07 29.8 0.1 2.4 2 0 0 2 2 2 2 mRNA capping enzyme, C-terminal domain Thioredoxin PF00085.15 AFZ79232.1 - 5.5e-08 32.4 0.2 7.7e-06 25.5 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_8 PF13905.1 AFZ79232.1 - 0.00041 20.4 1.5 0.15 12.1 0.1 3.3 2 1 1 3 3 3 1 Thioredoxin-like TrbC_Ftype PF09673.5 AFZ79232.1 - 0.001 18.6 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein Thioredoxin_2 PF13098.1 AFZ79232.1 - 0.037 14.2 0.0 0.76 10.0 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin-like domain Abhydrolase_5 PF12695.2 AFZ79233.1 - 3.9e-08 33.1 0.0 5.2e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AFZ79233.1 - 2e-05 24.6 0.0 2.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AFZ79233.1 - 4.5e-05 23.1 0.1 5.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.9 AFZ79235.1 - 1.9e-06 27.2 0.3 3.1e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_2 PF02230.11 AFZ79235.1 - 2.7e-06 27.0 0.5 0.00011 21.7 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 AFZ79235.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AFZ79235.1 - 0.059 12.5 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family FSH1 PF03959.8 AFZ79235.1 - 0.069 12.5 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) FAINT PF04385.10 AFZ79236.1 - 2.8e-44 148.8 42.5 3.7e-07 29.8 0.1 9.7 9 0 0 9 9 9 9 Domain of unknown function, DUF529 Lipase3_N PF03893.11 AFZ79237.1 - 0.13 12.0 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Lipase 3 N-terminal region NOPS PF08075.6 AFZ79238.1 - 0.022 15.1 0.3 0.062 13.7 0.2 1.8 2 0 0 2 2 2 0 NOPS (NUC059) domain FAINT PF04385.10 AFZ79239.1 - 2.9e-25 87.9 24.6 7.8e-07 28.8 1.3 6.7 5 1 1 6 6 6 5 Domain of unknown function, DUF529 Pam16 PF03656.8 AFZ79242.1 - 8.8e-11 41.7 0.0 9.8e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.26 AFZ79242.1 - 9.2e-10 38.1 0.0 1.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 AFZ79242.1 - 0.027 13.8 0.0 0.046 13.1 0.0 1.4 1 1 0 1 1 1 0 A repeated domain in UCH-protein eRF1_1 PF03463.10 AFZ79243.1 - 5.3e-22 77.7 0.0 1.2e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 AFZ79243.1 - 1.4e-17 64.2 0.1 2.3e-17 63.5 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 AFZ79243.1 - 1e-15 57.9 0.2 2.2e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 RRP7 PF12923.2 AFZ79244.1 - 1.5e-09 37.9 1.2 1.8e-09 37.7 0.2 1.5 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) PCI PF01399.22 AFZ79245.1 - 4.8e-08 33.2 0.0 1.1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain RNA_pol_Rpb4 PF03874.11 AFZ79246.1 - 1.9e-17 63.3 0.3 2.3e-17 63.0 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Nucleoporin_FG PF13634.1 AFZ79247.1 - 4e-33 114.0 158.7 1.5e-10 41.3 26.3 5.2 1 1 4 5 5 5 5 Nucleoporin FG repeat region Nsp1_C PF05064.8 AFZ79247.1 - 1.4e-12 47.2 4.8 4.2e-12 45.7 3.3 1.8 1 0 0 1 1 1 1 Nsp1-like C-terminal region NTP_transf_2 PF01909.18 AFZ79247.1 - 0.0018 18.5 0.0 0.0057 16.9 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Med4 PF10018.4 AFZ79247.1 - 0.0039 16.6 1.2 0.0039 16.6 0.8 2.1 1 1 1 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF745 PF05335.8 AFZ79247.1 - 0.027 14.0 3.5 0.045 13.2 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TMPIT PF07851.8 AFZ79247.1 - 0.18 10.8 3.3 0.3 10.1 2.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF16 PF01519.11 AFZ79247.1 - 0.6 10.3 5.0 0.61 10.3 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 LOH1CR12 PF10158.4 AFZ79247.1 - 0.92 9.3 5.2 0.99 9.2 0.6 2.4 2 1 1 3 3 3 0 Tumour suppressor protein DUF4164 PF13747.1 AFZ79247.1 - 2 8.6 6.9 1.6 8.9 0.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Fib_alpha PF08702.5 AFZ79247.1 - 2.3 8.3 8.9 0.78 9.8 1.1 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 AFZ79247.1 - 4 7.2 14.9 0.075 12.8 5.0 2.0 3 0 0 3 3 3 0 Tropomyosin like KxDL PF10241.4 AFZ79247.1 - 8.1 6.4 8.3 4.1 7.3 2.4 2.6 1 1 2 3 3 3 0 Uncharacterized conserved protein Lon_C PF05362.8 AFZ79248.1 - 7.5e-62 208.2 2.9 3.9e-53 179.8 0.0 2.8 3 0 0 3 3 3 2 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 AFZ79248.1 - 4e-30 105.0 0.1 9.6e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 AFZ79248.1 - 3.2e-20 72.6 0.0 1.7e-19 70.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 AFZ79248.1 - 1e-06 28.2 0.0 2.1e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 AFZ79248.1 - 2.4e-06 27.3 0.0 5.4e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 AFZ79248.1 - 1.6e-05 25.6 0.2 6.4e-05 23.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 AFZ79248.1 - 2.2e-05 23.3 0.7 0.00016 20.5 0.0 2.5 3 0 0 3 3 3 1 TIP49 C-terminus AAA_16 PF13191.1 AFZ79248.1 - 6.5e-05 23.0 0.6 0.00061 19.8 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 AFZ79248.1 - 7.3e-05 22.9 0.0 0.0043 17.2 0.0 2.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AFZ79248.1 - 0.00032 20.1 0.0 0.00064 19.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 AFZ79248.1 - 0.0015 18.3 0.5 0.015 15.2 0.0 2.9 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.1 AFZ79248.1 - 0.0016 17.8 0.6 0.02 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AFZ79248.1 - 0.0016 18.7 4.5 0.0052 17.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 AFZ79248.1 - 0.0024 16.9 0.0 0.0051 15.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_PrkA PF08298.6 AFZ79248.1 - 0.0031 16.2 0.0 0.0057 15.3 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain NTPase_1 PF03266.10 AFZ79248.1 - 0.017 14.8 0.0 0.064 12.9 0.0 2.0 1 1 1 2 2 2 0 NTPase AAA_19 PF13245.1 AFZ79248.1 - 0.018 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 AFZ79248.1 - 0.021 14.2 0.0 0.085 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_3 PF07726.6 AFZ79248.1 - 0.022 14.3 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 AFZ79248.1 - 0.042 13.5 0.1 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 AFZ79248.1 - 0.052 13.7 0.0 0.18 11.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase LSM PF01423.17 AFZ79249.1 - 3.3e-19 68.2 0.1 4.1e-19 67.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AFZ79249.1 - 0.0029 17.4 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Flag1_repress PF03614.8 AFZ79249.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Repressor of phase-1 flagellin FAINT PF04385.10 AFZ79251.1 - 9.5e-08 31.7 0.2 0.0016 18.2 0.1 3.4 3 0 0 3 3 3 2 Domain of unknown function, DUF529 Frataxin_Cyay PF01491.11 AFZ79251.1 - 0.0025 17.5 0.3 0.048 13.4 0.0 2.8 3 1 0 3 3 3 1 Frataxin-like domain EMA PF02488.10 AFZ79251.1 - 0.088 12.2 4.1 0.14 11.6 0.4 2.3 1 1 1 2 2 2 0 Merozoite Antigen SET PF00856.23 AFZ79253.1 - 8.6e-26 91.1 0.6 4.9e-25 88.7 0.4 2.3 1 1 0 1 1 1 1 SET domain Dicty_CTDC PF00526.13 AFZ79254.1 - 0.038 13.8 0.3 0.069 13.0 0.2 1.5 1 0 0 1 1 1 0 Dictyostelium (slime mold) repeat Spectrin PF00435.16 AFZ79254.1 - 0.13 12.5 0.4 0.25 11.6 0.2 1.6 1 0 0 1 1 1 0 Spectrin repeat Diphthamide_syn PF01866.12 AFZ79256.1 - 3.4e-89 299.1 0.1 3.3e-88 295.8 0.0 2.0 1 1 0 1 1 1 1 Putative diphthamide synthesis protein YTH PF04146.10 AFZ79257.1 - 2.3e-20 72.5 0.0 3.6e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain PWI PF01480.12 AFZ79258.1 - 1e-30 105.6 0.0 1.6e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 PWI domain DcpS_C PF11969.3 AFZ79259.1 - 0.00062 19.9 0.4 0.0027 17.9 0.3 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Ribosomal_L9_N PF01281.14 AFZ79260.1 - 1.7e-13 49.5 0.0 2.6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Rad52_Rad22 PF04098.10 AFZ79260.1 - 0.012 15.3 0.1 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein Ribosomal_L9_C PF03948.9 AFZ79260.1 - 0.017 15.1 0.0 0.041 13.9 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain plasmid_Toxin PF12703.2 AFZ79260.1 - 0.1 12.4 0.1 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system IBN_N PF03810.14 AFZ79260.1 - 0.12 12.3 0.0 0.66 9.9 0.0 2.0 2 0 0 2 2 2 0 Importin-beta N-terminal domain DSPc PF00782.15 AFZ79261.1 - 6.7e-17 61.3 0.0 1.1e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AFZ79261.1 - 0.0023 17.2 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase N2227 PF07942.7 AFZ79262.1 - 3.6e-91 304.9 0.0 4.9e-91 304.4 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.7 AFZ79262.1 - 0.034 14.6 0.0 0.15 12.5 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 AFZ79262.1 - 0.042 14.3 0.0 0.19 12.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DFP PF04127.10 AFZ79263.1 - 2.8e-09 36.8 0.4 4.3e-09 36.2 0.3 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Ribosomal_60s PF00428.14 AFZ79264.1 - 1.9e-23 82.6 9.7 2.2e-23 82.4 6.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Jag_N PF14804.1 AFZ79264.1 - 0.039 13.9 0.0 0.097 12.6 0.0 1.7 1 0 0 1 1 1 0 Jag N-terminus UMP1 PF05348.6 AFZ79265.1 - 4.6e-11 42.7 0.0 5.4e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 zf-CCCH PF00642.19 AFZ79266.1 - 0.0092 15.6 0.3 0.0092 15.6 0.2 2.0 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UDG PF03167.14 AFZ79267.1 - 2.8e-25 88.5 0.0 4e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF2048 PF09752.4 AFZ79267.1 - 0.047 12.5 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) RRM_1 PF00076.17 AFZ79268.1 - 2.3e-37 126.4 0.1 2.2e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ79268.1 - 3.1e-21 75.1 0.1 1.6e-12 47.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ79268.1 - 2e-20 72.3 0.0 5.2e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 AFZ79268.1 - 0.0016 17.9 0.1 0.22 11.0 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain Podoplanin PF05808.6 AFZ79269.1 - 8.4 5.9 7.4 15 5.0 5.1 1.3 1 0 0 1 1 1 0 Podoplanin PCI PF01399.22 AFZ79270.1 - 2.2e-13 50.4 2.0 4.8e-13 49.3 0.4 2.4 2 0 0 2 2 2 1 PCI domain RRM_1 PF00076.17 AFZ79271.1 - 5.1e-23 80.4 0.1 1.4e-11 43.8 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ79271.1 - 7.9e-15 54.4 0.2 1.5e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ79271.1 - 1.4e-14 53.8 0.0 1.2e-06 28.3 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AFZ79271.1 - 0.092 12.5 0.0 0.76 9.5 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 Pkinase PF00069.20 AFZ79272.1 - 5.2e-63 212.6 0.0 6.2e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ79272.1 - 1.2e-34 119.5 0.0 1.6e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AFZ79272.1 - 8e-06 25.0 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 AFZ79272.1 - 0.17 11.2 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL EF-hand_7 PF13499.1 AFZ79273.1 - 0.00045 20.2 1.5 0.077 13.1 0.4 3.5 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 AFZ79273.1 - 0.0067 16.2 0.0 0.9 9.5 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain TruB_N PF01509.13 AFZ79274.1 - 3.9e-43 147.1 0.0 5.3e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PI31_Prot_C PF08577.6 AFZ79275.1 - 0.017 15.7 4.1 0.033 14.8 0.0 2.3 2 0 0 2 2 2 0 PI31 proteasome regulator Ion_trans PF00520.26 AFZ79276.1 - 2.6e-10 39.9 30.1 4.4e-10 39.1 20.9 1.4 1 0 0 1 1 1 1 Ion transport protein LSM14 PF12701.2 AFZ79277.1 - 3.3e-30 103.7 0.1 3.4e-29 100.4 0.0 2.2 2 0 0 2 2 2 1 Scd6-like Sm domain SM-ATX PF14438.1 AFZ79277.1 - 5.9e-07 29.3 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.5 AFZ79277.1 - 0.014 15.8 0.5 0.03 14.8 0.1 1.6 1 1 0 1 1 1 0 FDF domain Tox-REase-2 PF15646.1 AFZ79277.1 - 0.09 12.6 0.1 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 WD40 PF00400.27 AFZ79278.1 - 1.3e-09 37.5 11.4 0.73 9.8 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat PD40 PF07676.7 AFZ79278.1 - 0.0077 15.8 1.8 12 5.6 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat YCII PF03795.9 AFZ79279.1 - 0.00082 19.5 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 2 YCII-related domain ABC_tran PF00005.22 AFZ79281.1 - 3.6e-31 108.2 0.0 1.9e-16 60.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter T2SE PF00437.15 AFZ79281.1 - 3.9e-05 22.7 0.8 0.091 11.6 0.2 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_30 PF13604.1 AFZ79281.1 - 0.0001 21.9 0.3 0.039 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AFZ79281.1 - 0.00012 22.1 0.1 0.073 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain UPF0079 PF02367.12 AFZ79281.1 - 0.00012 21.6 1.6 0.072 12.7 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 AFZ79281.1 - 0.00017 22.4 0.0 0.12 13.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AFZ79281.1 - 0.00027 21.2 0.3 0.14 12.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AFZ79281.1 - 0.00029 20.2 0.0 0.073 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AFZ79281.1 - 0.00035 20.0 1.6 0.74 9.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 AFZ79281.1 - 0.00052 19.2 1.4 0.38 9.9 0.1 2.7 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 AFZ79281.1 - 0.00082 19.4 0.4 0.025 14.5 0.0 7.3 7 2 1 9 9 8 2 AAA domain AAA_23 PF13476.1 AFZ79281.1 - 0.0011 19.3 16.1 0.045 14.0 1.1 4.0 3 1 1 4 4 4 2 AAA domain Miro PF08477.8 AFZ79281.1 - 0.0014 19.0 0.8 4.8 7.7 0.0 3.8 3 0 0 3 3 3 1 Miro-like protein AAA_22 PF13401.1 AFZ79281.1 - 0.0017 18.4 0.7 2.5 8.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 AFZ79281.1 - 0.0021 17.7 0.8 0.53 9.9 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 AFZ79281.1 - 0.0037 16.7 0.2 0.42 10.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 AFZ79281.1 - 0.0038 16.8 1.5 2.6 7.7 0.1 2.9 3 0 0 3 3 3 2 NACHT domain Zeta_toxin PF06414.7 AFZ79281.1 - 0.0041 16.2 0.3 2.2 7.3 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 AFZ79281.1 - 0.0047 16.6 3.6 0.71 9.6 0.2 2.5 2 0 0 2 2 2 2 Part of AAA domain DUF87 PF01935.12 AFZ79281.1 - 0.0084 15.9 2.2 0.22 11.3 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 SMC_N PF02463.14 AFZ79281.1 - 0.013 14.7 1.2 0.19 10.9 0.0 2.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ArgK PF03308.11 AFZ79281.1 - 0.024 13.4 0.1 0.024 13.4 0.1 1.7 2 0 0 2 2 2 0 ArgK protein SRP54 PF00448.17 AFZ79281.1 - 0.026 13.9 0.8 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 AFZ79281.1 - 0.031 14.1 0.0 0.085 12.7 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit cobW PF02492.14 AFZ79281.1 - 0.032 13.6 5.3 0.67 9.3 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 AFZ79281.1 - 0.094 12.4 1.0 10 5.7 0.1 2.5 2 0 0 2 2 2 0 NTPase TrwB_AAD_bind PF10412.4 AFZ79281.1 - 0.17 10.5 0.8 8.9 4.8 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 AFZ79281.1 - 0.18 11.6 0.1 7.4 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 AFZ79281.1 - 0.7 9.8 1.8 19 5.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain PRP21_like_P PF12230.3 AFZ79282.1 - 8.7e-41 139.9 8.6 4.2e-40 137.6 6.0 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 AFZ79282.1 - 5.3e-34 115.6 0.9 2.4e-16 59.0 0.0 2.4 2 0 0 2 2 2 2 Surp module DUF1682 PF07946.9 AFZ79282.1 - 0.0062 15.4 0.0 0.0062 15.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) Ribosomal_L20 PF00453.13 AFZ79286.1 - 4.2e-28 97.3 2.6 5.3e-28 97.0 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 Sec62 PF03839.11 AFZ79287.1 - 1.3e-23 83.5 2.8 1.8e-23 83.1 1.9 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 ubiquitin PF00240.18 AFZ79288.1 - 0.00046 19.5 0.7 0.52 9.7 0.0 3.4 2 2 0 2 2 2 2 Ubiquitin family TRAM_LAG1_CLN8 PF03798.11 AFZ79289.1 - 1.3e-23 83.6 13.0 2e-23 82.9 9.0 1.3 1 0 0 1 1 1 1 TLC domain Cytochrom_C PF00034.16 AFZ79290.1 - 5.4e-11 43.1 0.0 9.3e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 AFZ79290.1 - 1e-07 31.9 0.9 4.8e-07 29.8 0.6 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 AFZ79290.1 - 0.003 17.0 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c-550 domain Haem_bd PF14376.1 AFZ79290.1 - 0.11 12.1 0.1 0.23 11.1 0.0 1.5 2 0 0 2 2 2 0 Haem-binding domain Rad4 PF03835.10 AFZ79293.1 - 0.015 14.7 0.1 6.8 6.0 0.0 2.6 1 1 0 2 2 2 0 Rad4 transglutaminase-like domain UBA PF00627.26 AFZ79294.1 - 0.00049 19.8 0.6 0.0021 17.8 0.1 2.2 2 0 0 2 2 2 1 UBA/TS-N domain SpaB_C PF14028.1 AFZ79294.1 - 0.11 12.0 0.8 0.15 11.5 0.6 1.3 1 0 0 1 1 1 0 SpaB C-terminal domain FNIP_N PF14636.1 AFZ79294.1 - 9.3 6.7 10.5 15 6.0 5.8 2.0 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Pkinase PF00069.20 AFZ79295.1 - 2e-76 256.5 0.1 3.8e-76 255.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ79295.1 - 7.1e-40 136.7 0.0 1.2e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 AFZ79295.1 - 3.7e-26 91.0 7.2 4.7e-13 49.0 2.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AFZ79295.1 - 4.5e-26 88.1 12.8 1.3e-06 27.3 0.5 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 AFZ79295.1 - 9.2e-22 74.9 8.2 1.8e-05 24.2 0.5 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 AFZ79295.1 - 1.3e-19 68.5 14.2 8e-05 21.8 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 AFZ79295.1 - 5.2e-19 67.6 13.4 2.8e-07 30.0 0.5 4.8 2 1 3 5 5 5 4 EF-hand domain pair EF-hand_9 PF14658.1 AFZ79295.1 - 4.3e-06 26.5 1.0 0.0025 17.6 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain APH PF01636.18 AFZ79295.1 - 0.00052 19.8 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family SPARC_Ca_bdg PF10591.4 AFZ79295.1 - 0.00054 19.9 0.3 2 8.4 0.0 3.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 AFZ79295.1 - 0.0029 17.2 1.1 0.11 12.2 0.2 3.3 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand Kdo PF06293.9 AFZ79295.1 - 0.061 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIIC_sub6 PF10419.4 AFZ79296.1 - 0.0054 16.1 0.1 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit Oxysterol_BP PF01237.13 AFZ79297.1 - 1.8e-127 424.7 0.2 2.6e-127 424.1 0.1 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 AFZ79297.1 - 6e-10 39.2 0.6 2.3e-09 37.3 0.0 2.3 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 AFZ79297.1 - 0.002 18.3 0.6 0.52 10.5 0.4 3.1 1 1 0 1 1 1 1 Pleckstrin homology domain Arch_ATPase PF01637.13 AFZ79298.1 - 8.5e-05 22.3 0.0 0.0002 21.1 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 AFZ79298.1 - 0.00083 19.5 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AFZ79298.1 - 0.012 15.6 0.0 0.061 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF3728 PF12528.3 AFZ79298.1 - 0.05 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Prepilin peptidase dependent protein C (DUF3728) AAA PF00004.24 AFZ79298.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 AFZ79298.1 - 0.054 12.9 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 AFZ79298.1 - 0.17 11.2 0.0 9.2 5.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain SYF2 PF08231.7 AFZ79299.1 - 0.023 14.8 0.4 0.024 14.7 0.3 1.0 1 0 0 1 1 1 0 SYF2 splicing factor KKLCAg1 PF15204.1 AFZ79299.1 - 0.11 12.5 1.1 3.3 7.7 0.0 2.1 1 1 1 2 2 2 0 Kita-kyushu lung cancer antigen 1 Myb_DNA-binding PF00249.26 AFZ79300.1 - 4.2e-07 29.9 0.7 9e-07 28.8 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AFZ79300.1 - 0.0019 18.2 2.9 0.0046 17.0 0.2 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain TPR_11 PF13414.1 AFZ79301.1 - 2.6e-16 59.0 14.9 2.1e-08 33.6 1.0 2.8 2 1 2 4 4 3 3 TPR repeat Aha1_N PF09229.6 AFZ79301.1 - 4e-16 59.0 1.9 4e-16 59.0 1.4 2.5 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal TPR_2 PF07719.12 AFZ79301.1 - 5.9e-10 38.2 2.6 9.8e-06 25.1 0.4 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 AFZ79301.1 - 4.2e-08 33.4 0.1 1.1e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 AFZ79301.1 - 1.3e-06 27.7 3.1 4.7e-05 22.8 0.5 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 AFZ79301.1 - 1.4e-05 25.6 0.5 3.5e-05 24.3 0.1 1.9 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 AFZ79301.1 - 1.6e-05 25.0 0.0 0.00052 20.4 0.0 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 AFZ79301.1 - 2.3e-05 24.2 0.8 0.029 14.5 0.4 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ79301.1 - 0.00051 19.6 4.2 0.0016 18.0 0.1 3.8 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 AFZ79301.1 - 0.0015 18.4 2.2 1 9.3 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AFZ79301.1 - 0.0016 18.2 0.1 0.011 15.5 0.0 2.4 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 AFZ79301.1 - 0.0024 17.7 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 AFZ79301.1 - 0.0066 16.8 2.8 0.046 14.1 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 AFZ79301.1 - 0.0076 16.3 2.1 0.034 14.2 1.0 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 AFZ79301.1 - 0.044 13.8 0.9 0.12 12.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat YebO PF13974.1 AFZ79301.1 - 1.1 9.0 0.0 1.1 9.0 0.0 2.8 2 1 0 2 2 2 0 YebO-like protein IQ PF00612.22 AFZ79302.1 - 8.4e-20 68.4 32.2 4.1e-06 25.9 0.1 7.6 7 0 0 7 7 7 7 IQ calmodulin-binding motif RCC1 PF00415.13 AFZ79302.1 - 5.9e-16 58.4 0.3 8.8e-08 32.2 0.0 3.2 3 1 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AFZ79302.1 - 3.5e-12 45.5 11.8 9.2e-09 34.6 0.4 3.7 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat CwfJ_C_1 PF04677.10 AFZ79303.1 - 5.4e-15 55.1 1.5 1.1e-14 54.1 1.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 AFZ79303.1 - 9.8e-12 45.2 0.0 1.9e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF367 PF04034.8 AFZ79304.1 - 1.7e-45 153.6 0.0 2.5e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 AFZ79304.1 - 1e-11 44.1 0.0 1.5e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Med27 PF11571.3 AFZ79304.1 - 0.039 14.0 0.1 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 27 WD40 PF00400.27 AFZ79305.1 - 1.4e-36 123.0 11.5 9.2e-10 38.0 1.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 AFZ79305.1 - 0.00091 18.9 0.3 0.051 13.2 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nic96 PF04097.9 AFZ79306.1 - 0.0043 15.2 0.8 0.034 12.2 0.5 2.5 1 1 0 1 1 1 1 Nup93/Nic96 Carb_anhydrase PF00194.16 AFZ79307.1 - 4.5e-15 55.3 2.6 1.3e-12 47.2 0.0 3.7 4 0 0 4 4 4 3 Eukaryotic-type carbonic anhydrase DNA_pol_delta_4 PF04081.8 AFZ79307.1 - 0.038 14.2 2.7 0.15 12.3 1.9 2.1 1 0 0 1 1 1 0 DNA polymerase delta, subunit 4 CTNNBL PF08216.6 AFZ79308.1 - 9.5e-28 95.9 0.7 2.9e-27 94.3 0.5 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear DUF1840 PF08895.6 AFZ79308.1 - 0.14 12.2 0.5 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) TPR_11 PF13414.1 AFZ79309.1 - 1.1e-09 37.8 7.7 2.1e-09 36.8 4.4 2.1 1 1 0 1 1 1 1 TPR repeat DnaJ PF00226.26 AFZ79309.1 - 1.6e-08 34.1 0.0 5e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.23 AFZ79309.1 - 2e-08 33.4 10.5 0.00035 20.0 1.6 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AFZ79309.1 - 3.2e-07 29.7 10.8 0.0012 18.6 1.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AFZ79309.1 - 2e-06 27.6 3.9 0.011 15.6 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 AFZ79309.1 - 0.0078 16.8 0.0 0.03 14.9 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ79309.1 - 0.0096 15.6 7.5 0.56 10.1 1.8 3.6 2 1 0 2 2 2 1 Tetratricopeptide repeat CENP-F_leu_zip PF10473.4 AFZ79309.1 - 0.015 15.1 4.1 0.02 14.7 1.7 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_14 PF13428.1 AFZ79309.1 - 0.017 15.7 0.0 8.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Streptin-Immun PF11083.3 AFZ79309.1 - 0.048 13.6 5.8 0.22 11.5 1.8 3.4 2 1 1 3 3 3 0 Lantibiotic streptin immunity protein TPR_7 PF13176.1 AFZ79309.1 - 0.59 10.0 6.3 2.2 8.2 0.2 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 AFZ79309.1 - 0.69 10.5 3.0 1.6 9.3 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 AFZ79309.1 - 1.3 9.0 7.5 0.095 12.5 0.3 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 AFZ79309.1 - 2.3 8.1 6.1 0.44 10.4 1.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AFZ79309.1 - 3.8 7.4 8.5 8.8 6.3 0.7 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TSC22 PF01166.13 AFZ79310.1 - 0.076 12.9 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4577 PF15145.1 AFZ79310.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) EI24 PF07264.6 AFZ79310.1 - 4.1 6.7 16.6 7.2 5.9 11.5 1.4 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Clat_adaptor_s PF01217.15 AFZ79312.1 - 7.3e-36 123.0 3.9 7.9e-36 122.8 2.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF501 PF04417.7 AFZ79314.1 - 2.8e-14 53.1 0.0 6.5e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF501) NDK PF00334.14 AFZ79315.1 - 1.7e-52 176.8 0.0 1.9e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SRP54 PF00448.17 AFZ79316.1 - 8.7e-57 191.7 0.2 1.7e-56 190.7 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 AFZ79316.1 - 7.8e-14 51.7 13.4 1.8e-09 37.3 0.1 2.4 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal ArgK PF03308.11 AFZ79316.1 - 1.1e-06 27.6 0.1 3.2e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 ArgK protein CbiA PF01656.18 AFZ79316.1 - 1.3e-06 28.0 1.2 4.5e-06 26.2 0.9 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 AFZ79316.1 - 0.0001 21.9 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 AFZ79316.1 - 0.00032 20.4 0.4 0.069 12.8 0.0 3.4 2 1 1 3 3 3 1 NTPase DAP3 PF10236.4 AFZ79316.1 - 0.00056 18.9 0.8 0.0017 17.3 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.1 AFZ79316.1 - 0.0017 18.5 0.0 0.0097 16.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AFZ79316.1 - 0.0021 18.0 0.1 0.011 15.6 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain SRP54_N PF02881.14 AFZ79316.1 - 0.0037 17.3 0.4 0.029 14.4 0.0 2.8 1 1 1 2 2 2 1 SRP54-type protein, helical bundle domain Fer4_NifH PF00142.13 AFZ79316.1 - 0.0069 15.6 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.1 AFZ79316.1 - 0.019 14.8 1.2 6.1 6.7 0.0 4.3 3 2 1 4 4 4 0 AAA domain MobB PF03205.9 AFZ79316.1 - 0.021 14.5 0.1 0.1 12.2 0.0 2.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 AFZ79316.1 - 0.077 12.6 0.0 0.89 9.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain SUI1 PF01253.17 AFZ79320.1 - 4.5e-12 45.6 0.3 6.3e-12 45.1 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Peptidase_M41 PF01434.13 AFZ79321.1 - 1.1e-65 221.1 0.0 1.5e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AFZ79321.1 - 1.1e-41 142.1 0.0 2e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AFZ79321.1 - 4.7e-05 23.5 0.0 0.0035 17.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 AFZ79321.1 - 0.00013 20.8 0.1 0.00028 19.7 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 AFZ79321.1 - 0.00034 21.4 0.0 0.0012 19.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AFZ79321.1 - 0.0005 19.7 0.0 0.0024 17.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 AFZ79321.1 - 0.0023 17.0 0.0 0.0062 15.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus FtsH_ext PF06480.10 AFZ79321.1 - 0.003 17.7 0.1 0.094 12.9 0.1 2.7 1 1 0 1 1 1 1 FtsH Extracellular IstB_IS21 PF01695.12 AFZ79321.1 - 0.012 15.0 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.9 AFZ79321.1 - 0.015 15.1 0.1 0.097 12.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 AFZ79321.1 - 0.016 14.3 0.0 0.042 12.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 AFZ79321.1 - 0.017 15.1 0.1 0.073 13.0 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 AFZ79321.1 - 0.027 14.2 0.7 0.082 12.6 0.1 2.0 2 0 0 2 2 2 0 Part of AAA domain Mg_chelatase PF01078.16 AFZ79321.1 - 0.053 12.6 0.1 0.21 10.7 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 AFZ79321.1 - 0.061 13.2 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AFZ79321.1 - 0.065 13.5 0.1 0.21 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain NYD-SP28 PF14772.1 AFZ79321.1 - 0.074 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Sperm tail AAA_25 PF13481.1 AFZ79321.1 - 0.091 12.1 0.5 1.2 8.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 AFZ79321.1 - 0.095 12.5 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.1 AFZ79321.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 AFZ79321.1 - 0.15 11.4 0.0 0.41 10.1 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain MCM PF00493.18 AFZ79321.1 - 0.17 10.6 0.0 0.46 9.2 0.0 1.7 1 0 0 1 1 1 0 MCM2/3/5 family Peptidase_M50B PF13398.1 AFZ79321.1 - 0.21 10.9 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like DEAD PF00270.24 AFZ79322.1 - 6e-30 103.9 0.0 1.4e-29 102.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 AFZ79322.1 - 1.2e-19 69.6 1.3 3.4e-19 68.1 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 AFZ79322.1 - 4.5e-19 68.0 0.0 2e-18 66.0 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Peptidase_S46 PF10459.4 AFZ79322.1 - 0.00074 18.0 4.4 0.00099 17.6 3.0 1.1 1 0 0 1 1 1 1 Peptidase S46 ResIII PF04851.10 AFZ79322.1 - 0.022 14.6 2.5 0.065 13.0 0.0 2.8 2 2 0 2 2 2 0 Type III restriction enzyme, res subunit DUF1223 PF06764.6 AFZ79323.1 - 0.039 13.7 0.5 0.24 11.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1223) ThiF PF00899.16 AFZ79324.1 - 7.1e-34 116.5 0.8 1.7e-33 115.3 0.6 1.6 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 AFZ79324.1 - 0.0053 16.3 0.1 0.012 15.1 0.1 1.7 1 0 0 1 1 1 1 MoeZ/MoeB domain NAD_binding_7 PF13241.1 AFZ79324.1 - 0.011 16.0 0.3 0.043 14.0 0.1 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 AFZ79324.1 - 0.027 13.6 0.1 0.07 12.2 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sigma70_r1_1 PF03979.9 AFZ79324.1 - 0.033 14.1 0.0 0.09 12.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-70 factor, region 1.1 FAD_binding_3 PF01494.14 AFZ79324.1 - 0.057 12.4 0.6 0.057 12.4 0.4 1.5 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 AFZ79324.1 - 0.078 12.9 1.2 0.3 11.1 0.2 2.4 2 1 1 3 3 3 0 TrkA-N domain CS PF04969.11 AFZ79325.1 - 0.0035 17.8 0.0 0.0095 16.4 0.0 1.7 1 0 0 1 1 1 1 CS domain Integrin_beta PF00362.13 AFZ79325.1 - 0.03 13.2 0.1 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Integrin, beta chain Phi_1 PF04674.7 AFZ79325.1 - 0.066 12.3 0.1 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region tRNA-synt_His PF13393.1 AFZ79326.1 - 3.7e-30 105.0 0.0 5.8e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 AFZ79326.1 - 3.8e-14 52.6 0.0 6e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) eIF2A PF08662.6 AFZ79327.1 - 4.9e-53 179.7 1.1 6.7e-51 172.7 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Brix PF04427.13 AFZ79328.1 - 3.9e-42 144.0 4.5 3.9e-42 144.0 3.2 1.7 2 1 0 2 2 2 1 Brix domain Rep_fac-A_C PF08646.5 AFZ79330.1 - 1.4e-23 83.2 2.3 1.9e-23 82.8 0.6 2.0 1 1 0 1 1 1 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 AFZ79330.1 - 3.1e-07 30.1 0.0 1e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 AFZ79330.1 - 0.0038 17.2 0.1 0.017 15.1 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function DUF223 ATP_bind_4 PF01902.12 AFZ79331.1 - 2e-39 135.2 0.0 7e-39 133.4 0.0 1.7 1 1 0 1 1 1 1 ATP-binding region ATP-synt_F PF01990.12 AFZ79332.1 - 1.9e-30 105.0 0.2 2.5e-30 104.7 0.2 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit eIF-5_eIF-2B PF01873.12 AFZ79332.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain found in IF2B/IF5 zf-DHHC PF01529.15 AFZ79333.1 - 1.6e-41 141.6 15.0 1.6e-41 141.6 10.4 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase NADH_dehy_S2_C PF06444.6 AFZ79333.1 - 0.16 12.3 0.2 0.16 12.3 0.1 2.5 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 C-terminus Colicin_V PF02674.11 AFZ79333.1 - 0.46 10.3 13.4 0.93 9.3 1.6 2.2 2 0 0 2 2 2 0 Colicin V production protein PRA1 PF03208.14 AFZ79333.1 - 7.7 5.8 11.6 1.1 8.5 1.5 2.3 2 0 0 2 2 2 0 PRA1 family protein DUF3223 PF11523.3 AFZ79335.1 - 2.4e-11 43.7 0.1 5.6e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3223) La PF05383.12 AFZ79335.1 - 1.3e-07 31.2 0.3 4.6e-07 29.5 0.2 2.0 1 0 0 1 1 1 1 La domain LisH PF08513.6 AFZ79336.1 - 6.3e-12 44.8 0.1 1.3e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 LisH WD40 PF00400.27 AFZ79336.1 - 9.3e-11 41.1 11.1 0.017 15.0 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 AFZ79336.1 - 2.9e-07 30.3 2.6 0.0081 15.8 0.1 3.6 2 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.1 AFZ79336.1 - 0.0023 17.0 0.0 0.78 8.6 0.0 2.2 1 1 1 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus CDT1 PF08839.6 AFZ79337.1 - 1.2e-19 70.8 0.0 3.3e-19 69.4 0.0 1.7 2 0 0 2 2 2 1 DNA replication factor CDT1 like DUF2036 PF09724.4 AFZ79338.1 - 1e-05 24.8 0.5 0.00026 20.2 0.3 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2036) Ctf8 PF09696.5 AFZ79338.1 - 0.00028 20.6 0.0 0.00088 19.0 0.0 2.0 1 1 0 1 1 1 1 Ctf8 LisH PF08513.6 AFZ79339.1 - 6.3e-12 44.8 0.1 1.3e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 LisH WD40 PF00400.27 AFZ79339.1 - 9.3e-11 41.1 11.1 0.017 15.0 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 AFZ79339.1 - 5.5e-07 29.4 2.9 0.0082 15.8 0.2 3.6 2 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.1 AFZ79339.1 - 0.0092 15.0 0.0 2.1 7.2 0.0 2.2 1 1 1 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus CDT1 PF08839.6 AFZ79340.1 - 1.2e-19 70.8 0.0 3.3e-19 69.4 0.0 1.7 2 0 0 2 2 2 1 DNA replication factor CDT1 like Mito_carr PF00153.22 AFZ79341.1 - 2.8e-54 180.8 0.3 6.3e-17 61.0 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF1358 PF07096.6 AFZ79341.1 - 0.015 15.0 0.0 0.094 12.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1358) GTP1_OBG PF01018.17 AFZ79342.1 - 2.6e-16 59.6 0.2 3.7e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 AFZ79342.1 - 8.6e-12 45.0 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AFZ79342.1 - 4.6e-07 29.2 0.0 9.6e-07 28.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 AFZ79342.1 - 0.00084 18.6 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 AFZ79342.1 - 0.0044 16.1 0.0 0.0061 15.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 AFZ79342.1 - 0.066 13.0 0.2 1.1 9.0 0.0 2.1 1 1 0 2 2 2 0 Dynamin family Ubiq_cyt_C_chap PF03981.7 AFZ79343.1 - 1.1e-25 90.1 0.1 1.8e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone RNase_T PF00929.19 AFZ79345.1 - 1e-20 74.6 0.5 9e-20 71.5 0.0 2.7 3 0 0 3 3 3 1 Exonuclease Mon1 PF03164.9 AFZ79346.1 - 7.6e-59 199.3 1.1 9.4e-59 199.0 0.8 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 ABC_tran PF00005.22 AFZ79347.1 - 5.7e-34 117.3 0.0 1.6e-33 115.9 0.0 1.8 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.18 AFZ79347.1 - 2.7e-22 79.4 16.6 4.3e-22 78.8 11.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 AFZ79347.1 - 4.8e-08 33.3 3.9 0.00069 19.6 0.0 3.2 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 AFZ79347.1 - 9.6e-08 31.5 0.0 0.0001 21.6 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 AFZ79347.1 - 0.00016 21.8 0.0 0.0044 17.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AFZ79347.1 - 0.00032 20.7 0.0 0.00065 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 AFZ79347.1 - 0.00067 20.4 0.0 0.0015 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 AFZ79347.1 - 0.0015 17.5 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 AFZ79347.1 - 0.0016 17.9 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 AFZ79347.1 - 0.0047 16.6 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 AFZ79347.1 - 0.0054 17.0 0.0 0.091 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AFZ79347.1 - 0.0057 15.8 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 AFZ79347.1 - 0.029 13.8 0.1 0.06 12.8 0.1 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 AFZ79347.1 - 0.033 14.0 0.1 0.58 10.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AFZ79347.1 - 0.057 12.8 0.1 0.17 11.3 0.1 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 AFZ79347.1 - 0.066 13.5 0.5 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 AFZ79347.1 - 0.1 12.5 0.1 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arm PF00514.18 AFZ79348.1 - 0.00053 19.7 0.0 0.19 11.5 0.0 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat RNA_pol_A_CTD PF03118.10 AFZ79348.1 - 0.0015 17.9 0.7 0.0053 16.1 0.5 2.0 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain NusB PF01029.13 AFZ79348.1 - 1.2 9.1 7.2 0.5 10.3 0.7 2.7 2 1 1 3 3 3 0 NusB family Pkinase PF00069.20 AFZ79349.1 - 9.8e-13 47.8 0.0 4.9e-11 42.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Rcd1 PF04078.8 AFZ79350.1 - 4.4e-119 396.1 1.9 5.1e-119 395.9 1.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like DNA_RNApol_7kD PF03604.8 AFZ79351.1 - 0.022 14.2 3.9 0.041 13.3 2.7 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 AFZ79351.1 - 0.05 13.2 1.4 0.08 12.6 1.0 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_6 PF14599.1 AFZ79351.1 - 0.1 12.4 3.9 0.18 11.5 2.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon Lar_restr_allev PF14354.1 AFZ79351.1 - 0.12 12.7 4.4 0.42 10.9 3.0 2.1 1 1 0 1 1 1 0 Restriction alleviation protein Lar Nudix_N_2 PF14803.1 AFZ79351.1 - 1 9.0 5.6 0.42 10.3 0.8 2.2 2 0 0 2 2 2 0 Nudix N-terminal Hepcidin PF06446.7 AFZ79351.1 - 3.5 8.1 7.2 0.25 11.7 1.1 2.0 2 1 1 3 3 3 0 Hepcidin Tubulin PF00091.20 AFZ79352.1 - 4e-73 245.7 0.0 6.5e-73 245.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AFZ79352.1 - 6.3e-49 165.2 0.3 9.6e-49 164.6 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 AFZ79352.1 - 1.6e-05 24.9 0.0 3.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 AFZ79352.1 - 0.0036 16.7 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain FHA PF00498.21 AFZ79353.1 - 3.7e-16 58.9 0.3 1e-15 57.5 0.1 1.9 2 0 0 2 2 2 1 FHA domain ATG16 PF08614.6 AFZ79354.1 - 0.0015 18.4 12.6 0.0031 17.3 3.2 2.4 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 AFZ79354.1 - 0.0039 17.0 15.9 0.0086 15.9 4.6 2.3 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.1 AFZ79354.1 - 0.0053 16.8 10.3 0.22 11.6 2.3 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4164) DUF2968 PF11180.3 AFZ79354.1 - 0.0086 15.4 9.3 0.045 13.1 1.8 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2968) DUF1204 PF06721.6 AFZ79354.1 - 0.0087 15.3 2.9 0.018 14.2 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1204) IncA PF04156.9 AFZ79354.1 - 0.011 15.3 7.6 0.011 15.3 5.3 2.2 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 AFZ79354.1 - 0.032 13.4 17.6 0.24 10.5 5.2 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 AFZ79354.1 - 0.1 12.3 12.8 0.5 10.1 0.7 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper ADIP PF11559.3 AFZ79354.1 - 0.26 11.2 18.6 0.68 9.8 5.6 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 AFZ79354.1 - 0.26 10.3 20.1 0.018 14.1 5.8 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 DivIC PF04977.10 AFZ79354.1 - 0.28 10.6 17.1 0.3 10.5 0.8 3.5 2 1 1 3 3 3 0 Septum formation initiator DUF972 PF06156.8 AFZ79354.1 - 0.29 11.4 14.2 3.2 8.1 0.8 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Cep57_CLD_2 PF14197.1 AFZ79354.1 - 0.71 9.8 16.2 0.09 12.7 1.7 3.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.16 AFZ79354.1 - 2 8.4 20.7 1.3 9.0 0.5 3.5 2 1 1 3 3 3 0 bZIP transcription factor DivIVA PF05103.8 AFZ79354.1 - 2.8 8.0 17.0 2 8.5 0.1 3.4 2 1 0 3 3 3 0 DivIVA protein DUF904 PF06005.7 AFZ79354.1 - 2.9 8.2 24.0 0.39 11.0 2.0 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Seryl_tRNA_N PF02403.17 AFZ79354.1 - 5.2 7.1 15.8 0.62 10.1 4.4 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DNA_topoisoIV PF00521.15 AFZ79356.1 - 5.2e-127 424.2 0.0 1e-126 423.2 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 AFZ79356.1 - 7.8e-34 116.3 2.3 1.7e-33 115.2 1.6 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 AFZ79356.1 - 1.1e-11 44.6 0.0 3.6e-11 42.9 0.0 2.0 1 0 0 1 1 1 1 Toprim domain IspD PF01128.14 AFZ79356.1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase V-SNARE_C PF12352.3 AFZ79358.1 - 2.1e-06 27.6 2.1 3.1e-06 27.1 1.4 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 AFZ79358.1 - 0.033 13.8 1.0 0.067 12.8 0.7 1.7 1 1 0 1 1 1 0 Sec20 Synaptobrevin PF00957.16 AFZ79358.1 - 0.52 9.9 2.6 0.8 9.3 1.8 1.5 1 1 0 1 1 1 0 Synaptobrevin DNA_pol_E_B PF04042.11 AFZ79359.1 - 2.1e-30 105.5 0.2 5.3e-29 100.9 0.1 2.9 2 1 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B IncA PF04156.9 AFZ79360.1 - 0.18 11.3 5.7 0.28 10.7 4.0 1.3 1 0 0 1 1 1 0 IncA protein Cupin_8 PF13621.1 AFZ79361.1 - 2.1e-30 106.0 0.0 2.7e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 AFZ79361.1 - 7.2e-05 22.1 0.1 0.00019 20.8 0.1 1.6 1 1 0 1 1 1 1 Cupin superfamily protein DUF1625 PF07787.7 AFZ79364.1 - 2.4e-30 105.6 0.0 4.4e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1625) DAGK_acc PF00609.14 AFZ79366.1 - 1.2e-29 103.5 0.0 1.8e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 AFZ79366.1 - 6.2e-17 61.2 0.0 1.5e-16 59.9 0.0 1.6 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain TPR_16 PF13432.1 AFZ79367.1 - 4.1e-21 75.0 6.7 4.4e-05 24.0 0.0 8.3 7 2 1 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 AFZ79367.1 - 9e-21 72.4 6.5 0.016 15.7 0.0 12.1 5 3 9 14 14 12 6 Tetratricopeptide repeat TPR_19 PF14559.1 AFZ79367.1 - 1.4e-16 60.5 0.0 0.004 17.4 0.0 6.7 9 0 0 9 9 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 AFZ79367.1 - 3.9e-13 48.2 20.7 0.02 14.7 0.0 10.5 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_11 PF13414.1 AFZ79367.1 - 2.3e-12 46.3 9.6 0.00027 20.4 0.0 6.9 5 3 1 7 7 7 3 TPR repeat TPR_8 PF13181.1 AFZ79367.1 - 9.1e-12 43.8 5.4 0.46 10.3 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat HAT PF02184.11 AFZ79367.1 - 2.4e-11 43.1 55.8 6.1e-05 22.6 0.0 10.9 12 1 0 12 12 11 5 HAT (Half-A-TPR) repeat Suf PF05843.9 AFZ79367.1 - 9.1e-11 42.0 18.4 0.0002 21.2 0.1 5.9 2 2 4 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.1 AFZ79367.1 - 1.2e-10 40.6 6.2 0.0064 16.5 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 AFZ79367.1 - 2.2e-10 40.3 4.6 0.024 14.5 0.0 7.8 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 AFZ79367.1 - 1.7e-07 30.5 10.1 3.7 7.3 0.0 7.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 AFZ79367.1 - 9.9e-07 28.1 8.9 0.8 9.6 0.0 8.2 11 0 0 11 11 9 2 Tetratricopeptide repeat NRDE-2 PF08424.5 AFZ79367.1 - 7.2e-05 21.8 12.9 0.013 14.4 0.0 5.1 4 3 2 6 6 6 2 NRDE-2, necessary for RNA interference TPR_6 PF13174.1 AFZ79367.1 - 0.00021 21.5 11.7 11 6.7 0.1 8.2 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_15 PF13429.1 AFZ79367.1 - 0.00068 18.7 5.9 0.081 11.9 0.5 3.9 3 1 0 4 4 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 AFZ79367.1 - 0.0024 17.6 15.9 0.33 10.7 0.3 5.6 4 3 1 5 5 5 1 Mad3/BUB1 homology region 1 Fis1_TPR_C PF14853.1 AFZ79367.1 - 0.028 14.2 0.0 24 4.9 0.0 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 AFZ79367.1 - 0.066 13.6 0.0 1.2 9.7 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 AFZ79367.1 - 0.11 12.3 19.9 0.28 10.9 0.3 6.1 5 2 1 6 6 6 0 U3 small nucleolar RNA-associated protein 6 FAINT PF04385.10 AFZ79368.1 - 1.4e-07 31.2 0.1 2.2e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79369.1 - 2e-06 27.5 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Ribosomal_L41 PF05162.8 AFZ79369.1 - 6.9 6.4 10.7 12 5.6 7.4 1.4 1 0 0 1 1 1 0 Ribosomal protein L41 FAINT PF04385.10 AFZ79370.1 - 2.1e-15 56.3 12.2 7.8e-08 32.0 1.5 3.2 2 1 1 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79372.1 - 9.6e-40 134.3 70.4 2.3e-06 27.3 3.2 13.6 12 1 0 12 12 12 11 Domain of unknown function, DUF529 PBP1_TM PF14812.1 AFZ79372.1 - 0.0012 19.0 1.3 0.004 17.4 0.9 1.9 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 AFZ79372.1 - 2.9 7.0 9.6 5.2 6.2 6.7 1.3 1 0 0 1 1 1 0 NOA36 protein AP2 PF00847.15 AFZ79374.1 - 7.4e-11 42.0 0.7 9.9e-05 22.4 0.1 2.4 2 0 0 2 2 2 2 AP2 domain Med14 PF08638.6 AFZ79375.1 - 0.00053 19.2 0.0 0.0012 18.1 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 SF3b10 PF07189.6 AFZ79376.1 - 9.4e-34 115.0 0.3 1.3e-33 114.6 0.1 1.3 1 1 1 2 2 2 1 Splicing factor 3B subunit 10 (SF3b10) E1-E2_ATPase PF00122.15 AFZ79377.1 - 0.0055 15.7 0.0 0.015 14.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase PLAC8 PF04749.12 AFZ79377.1 - 7.5 7.1 12.8 0.64 10.5 0.1 3.7 4 0 0 4 4 4 0 PLAC8 family FAINT PF04385.10 AFZ79379.1 - 1.7e-14 53.3 9.4 5.6e-06 26.1 1.1 4.2 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 AFZ79379.1 - 5.2e-08 33.0 0.0 1.1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ79379.1 - 4e-07 29.8 0.0 1.1e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ79379.1 - 4.2e-06 26.5 0.0 2.1e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 AFZ79379.1 - 0.0013 18.2 0.2 0.73 9.2 0.1 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase UPF0565 PF10561.4 AFZ79379.1 - 0.0013 17.6 0.0 0.0021 17.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 Abhydrolase_1 PF00561.15 AFZ79379.1 - 0.019 14.5 0.1 0.3 10.5 0.0 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AFZ79379.1 - 0.065 12.4 0.3 0.45 9.6 0.1 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1450 PF07293.6 AFZ79380.1 - 0.058 13.3 0.8 0.061 13.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) TIG PF01833.19 AFZ79381.1 - 0.017 15.0 0.1 1.3 9.0 0.0 3.4 2 1 1 3 3 3 0 IPT/TIG domain Leo1 PF04004.8 AFZ79383.1 - 4.3e-21 75.3 0.4 7.2e-21 74.6 0.2 1.4 1 0 0 1 1 1 1 Leo1-like protein DUF2433 PF10360.4 AFZ79384.1 - 0.0013 19.0 2.7 0.21 11.8 0.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2433) S_layer_C PF05124.7 AFZ79384.1 - 0.036 13.7 0.5 0.061 12.9 0.1 1.5 1 1 0 1 1 1 0 S-layer like family, C-terminal region Laminin_II PF06009.7 AFZ79384.1 - 0.037 13.7 3.0 0.05 13.3 1.6 1.5 1 1 0 1 1 1 0 Laminin Domain II Mod_r PF07200.8 AFZ79384.1 - 0.065 13.1 0.8 0.065 13.1 0.5 2.1 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CM_2 PF01817.16 AFZ79384.1 - 0.15 12.1 3.3 1.3 9.1 0.4 2.8 3 0 0 3 3 3 0 Chorismate mutase type II Seryl_tRNA_N PF02403.17 AFZ79384.1 - 0.23 11.4 4.5 7.1 6.6 0.8 3.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 AFZ79384.1 - 0.53 9.1 7.0 0.92 8.3 4.8 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 AFZ79384.1 - 7.5 6.9 8.0 1.1 9.5 0.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) RAP PF08373.5 AFZ79385.1 - 4.9e-09 35.8 0.0 1.5e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 RAP domain CS PF04969.11 AFZ79386.1 - 3.4e-08 33.9 0.1 5.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 CS domain Ribosomal_S6e PF01092.14 AFZ79387.1 - 1.3e-54 183.2 0.2 2.3e-54 182.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e KOG2701 PF09762.4 AFZ79387.1 - 0.046 13.7 1.4 0.063 13.3 0.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) FAINT PF04385.10 AFZ79388.1 - 0.0085 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Brevenin PF03032.10 AFZ79388.1 - 0.13 12.0 0.7 0.32 10.8 0.5 1.6 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family ATP-synt_D PF01813.12 AFZ79389.1 - 3.8e-55 186.4 1.6 4.6e-55 186.2 1.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit D ABC_tran PF00005.22 AFZ79391.1 - 3.4e-29 101.9 0.0 2.7e-15 56.8 0.0 2.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AFZ79391.1 - 2.2e-05 24.6 9.1 0.02 14.8 0.1 4.4 6 0 0 6 6 4 2 AAA domain AAA_16 PF13191.1 AFZ79391.1 - 4.5e-05 23.5 0.0 0.054 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 AFZ79391.1 - 5.7e-05 23.5 1.7 0.046 14.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AFZ79391.1 - 0.00011 21.6 1.4 0.18 11.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 AFZ79391.1 - 0.00016 22.5 0.0 0.19 12.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AFZ79391.1 - 0.00032 20.9 0.1 1.4 9.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 AFZ79391.1 - 0.00033 20.1 0.0 0.048 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AFZ79391.1 - 0.0011 17.9 0.5 0.87 8.4 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_30 PF13604.1 AFZ79391.1 - 0.0014 18.2 0.1 0.32 10.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 AFZ79391.1 - 0.0021 16.8 0.7 0.0045 15.7 0.0 1.7 2 0 0 2 2 2 1 ArgK protein AAA_15 PF13175.1 AFZ79391.1 - 0.0029 16.7 0.2 6.7 5.6 0.1 3.4 3 0 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.12 AFZ79391.1 - 0.0039 17.0 4.2 0.073 12.8 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function DUF87 DUF258 PF03193.11 AFZ79391.1 - 0.0044 16.2 0.2 0.58 9.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 AFZ79391.1 - 0.0045 16.0 0.2 2.5 7.1 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin UPF0079 PF02367.12 AFZ79391.1 - 0.0046 16.5 0.6 0.17 11.5 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 AFZ79391.1 - 0.0064 16.1 0.5 0.81 9.3 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 AFZ79391.1 - 0.007 15.8 0.2 0.74 9.2 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 AFZ79391.1 - 0.0078 16.7 0.1 3.3 8.2 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 AFZ79391.1 - 0.0085 15.7 0.5 2.2 7.8 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 AFZ79391.1 - 0.0095 16.0 0.0 7.2 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 AFZ79391.1 - 0.015 15.1 0.3 3 7.6 0.0 2.7 2 0 0 2 2 2 0 Dynamin family SMC_N PF02463.14 AFZ79391.1 - 0.016 14.4 1.0 0.16 11.1 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 AFZ79391.1 - 0.042 13.7 0.2 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 AFZ79391.1 - 0.044 13.7 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 AFZ79391.1 - 0.044 13.5 1.2 3.9 7.2 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 AFZ79391.1 - 0.055 13.3 0.1 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 AFZ79391.1 - 0.092 12.2 0.1 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.14 AFZ79391.1 - 0.4 10.1 5.1 11 5.4 0.2 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF544 PF04424.8 AFZ79392.1 - 7.6e-11 41.8 0.0 1.6e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Sec63 PF02889.11 AFZ79393.1 - 1.2e-45 156.1 0.0 1.7e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 AFZ79393.1 - 6.3e-20 70.6 0.2 1.5e-19 69.5 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain Rep_Org_C PF06926.6 AFZ79393.1 - 0.012 15.7 0.4 1.4 9.0 0.1 2.6 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus DUF3149 PF11346.3 AFZ79393.1 - 0.065 12.7 1.0 0.15 11.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) TcdB_toxin_midC PF12255.3 AFZ79393.1 - 0.087 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/C-terminal region DUF1327 PF07041.6 AFZ79394.1 - 0.027 14.3 1.2 0.19 11.6 0.1 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF1327) Sugarporin_N PF11471.3 AFZ79394.1 - 0.029 14.0 1.5 0.029 14.0 1.0 3.3 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Reo_sigmaC PF04582.7 AFZ79394.1 - 0.17 11.0 7.5 0.27 10.3 2.7 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein SlyX PF04102.7 AFZ79394.1 - 0.35 11.2 9.9 5.3 7.5 1.5 4.5 3 1 2 5 5 5 0 SlyX NYD-SP28 PF14772.1 AFZ79394.1 - 2.6 8.2 27.1 0.43 10.7 0.3 4.2 1 1 3 4 4 4 0 Sperm tail Cortex-I_coil PF09304.5 AFZ79394.1 - 2.7 8.0 29.6 1.1 9.2 8.0 3.5 1 1 1 3 3 3 0 Cortexillin I, coiled coil TEX13 PF15186.1 AFZ79394.1 - 4.4 6.8 13.5 0.042 13.4 2.1 2.6 2 1 0 3 3 3 0 Testis-expressed sequence 13 protein family Solute_trans_a PF03619.11 AFZ79396.1 - 1.1e-48 165.9 17.0 1.4e-48 165.5 11.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha NAF PF03822.9 AFZ79396.1 - 0.047 13.4 0.1 0.047 13.4 0.1 1.9 2 0 0 2 2 2 0 NAF domain cNMP_binding PF00027.24 AFZ79397.1 - 3.6e-40 135.6 0.1 1e-21 76.4 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain YojJ PF10372.4 AFZ79397.1 - 0.051 13.4 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Caldesmon PF02029.10 AFZ79400.1 - 0.16 10.3 20.0 0.2 10.0 13.9 1.3 1 0 0 1 1 1 0 Caldesmon DUF4551 PF15087.1 AFZ79400.1 - 0.22 9.8 9.2 0.25 9.6 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Asp-B-Hydro_N PF05279.6 AFZ79400.1 - 0.69 9.7 14.6 0.8 9.5 10.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AP2 PF00847.15 AFZ79401.1 - 1.2e-06 28.5 0.2 2.8e-06 27.3 0.2 1.7 1 0 0 1 1 1 1 AP2 domain ALMT PF11744.3 AFZ79401.1 - 0.022 13.4 0.1 0.042 12.5 0.1 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter DEAD PF00270.24 AFZ79402.1 - 5.6e-40 136.5 0.2 5.1e-39 133.4 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ79402.1 - 5.4e-21 74.2 0.0 1.4e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 AFZ79402.1 - 5.2e-07 29.0 0.0 1.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 AFZ79402.1 - 0.00044 20.1 3.1 0.0033 17.2 0.0 3.3 2 2 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AFZ79402.1 - 0.0087 16.1 0.3 0.075 13.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain Daxx PF03344.10 AFZ79402.1 - 1.5 7.2 20.7 2.2 6.6 14.4 1.1 1 0 0 1 1 1 0 Daxx Family CAF1A PF12253.3 AFZ79403.1 - 6.5e-09 35.7 5.1 2.2e-08 34.1 3.5 1.8 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A PHO4 PF01384.15 AFZ79405.1 - 1.5e-100 336.0 13.5 1.9e-100 335.6 9.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF3357 PF11837.3 AFZ79405.1 - 0.62 9.9 2.8 3 7.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) DUF2570 PF10828.3 AFZ79406.1 - 0.0069 15.9 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) TBCA PF02970.11 AFZ79406.1 - 0.0094 16.0 3.2 1.4 9.0 0.2 2.5 1 1 1 2 2 2 2 Tubulin binding cofactor A DUF1993 PF09351.5 AFZ79406.1 - 0.077 12.9 0.0 0.71 9.7 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) KLRAQ PF10205.4 AFZ79406.1 - 0.68 9.9 6.3 0.27 11.2 0.3 2.6 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein cNMP_binding PF00027.24 AFZ79407.1 - 1.8e-32 110.9 1.0 4.8e-09 35.9 0.0 5.0 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain EF-hand_8 PF13833.1 AFZ79407.1 - 0.00039 19.9 0.1 0.77 9.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 AFZ79407.1 - 0.0012 18.9 1.4 0.088 12.9 0.0 3.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 AFZ79407.1 - 0.0074 15.5 0.1 0.04 13.2 0.1 2.4 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 AFZ79407.1 - 0.0086 15.3 0.1 0.0086 15.3 0.0 4.4 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.1 AFZ79407.1 - 0.077 12.9 0.0 0.077 12.9 0.0 4.0 5 0 0 5 5 5 0 EF-hand domain HSA PF07529.8 AFZ79409.1 - 9.8e-08 31.6 0.4 2.4e-07 30.4 0.3 1.7 1 0 0 1 1 1 1 HSA GlutR_N PF05201.10 AFZ79409.1 - 0.021 14.3 0.1 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain Peptidase_C54 PF03416.14 AFZ79410.1 - 1.3e-31 109.8 0.0 1.9e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 FAINT PF04385.10 AFZ79411.1 - 4.7e-20 71.2 9.0 7.5e-07 28.9 0.2 4.1 3 1 1 4 4 4 3 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79411.1 - 1.3e-05 24.7 2.8 1.3e-05 24.7 0.4 1.9 2 0 0 2 2 2 1 Merozoite Antigen Not1 PF04054.10 AFZ79412.1 - 1.2e-41 142.8 11.3 1.6e-40 139.1 6.2 2.8 2 1 0 2 2 2 2 CCR4-Not complex component, Not1 DUF3819 PF12842.2 AFZ79412.1 - 2.1e-26 92.4 0.7 3.4e-25 88.4 0.4 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) DKCLD PF08068.7 AFZ79413.1 - 2e-28 98.0 0.0 1.1e-27 95.6 0.0 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 AFZ79413.1 - 8.4e-25 87.6 0.3 7.2e-22 78.1 0.2 3.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 AFZ79413.1 - 1.3e-17 63.3 2.5 2.9e-17 62.1 1.7 1.7 1 0 0 1 1 1 1 PUA domain DEAD PF00270.24 AFZ79414.1 - 5.3e-21 74.8 0.0 9.9e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ79414.1 - 8.3e-19 67.2 0.0 1.9e-17 62.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 AFZ79415.1 - 5.8e-09 35.6 5.2 8.6e-09 35.0 3.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AFZ79415.1 - 2.2e-05 24.3 7.0 3.4e-05 23.7 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AFZ79415.1 - 0.00021 20.9 5.1 0.00033 20.2 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AFZ79415.1 - 0.0014 18.4 0.2 0.0028 17.4 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 AFZ79415.1 - 0.0033 17.4 2.4 0.011 15.8 1.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 AFZ79415.1 - 0.0041 16.6 2.7 0.008 15.6 1.9 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 AFZ79415.1 - 0.0041 16.7 3.0 0.0068 16.0 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AFZ79415.1 - 0.0065 16.1 3.3 0.016 14.9 2.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain PHD PF00628.24 AFZ79415.1 - 0.014 15.0 0.7 0.023 14.3 0.5 1.3 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 AFZ79415.1 - 0.015 14.9 1.8 0.022 14.4 0.1 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 AFZ79415.1 - 0.092 12.6 6.1 0.14 12.0 4.3 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Di19 PF05605.7 AFZ79415.1 - 0.23 11.6 2.2 15 5.7 0.3 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING-like PF08746.6 AFZ79415.1 - 0.34 10.9 4.5 0.19 11.7 0.7 2.1 2 0 0 2 2 2 0 RING-like domain Dpy19 PF10034.4 AFZ79416.1 - 6.9e-53 179.8 34.8 3.2e-39 134.6 16.3 2.0 1 1 1 2 2 2 2 Q-cell neuroblast polarisation DUF1370 PF07114.6 AFZ79416.1 - 0.0025 17.0 0.4 0.0054 15.9 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1370) Dpy19 PF10034.4 AFZ79417.1 - 1e-24 86.7 1.3 1.4e-24 86.3 0.9 1.1 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Fmp27_SW PF10305.4 AFZ79417.1 - 0.044 14.2 0.1 0.82 10.1 0.0 2.7 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain SKIP_SNW PF02731.10 AFZ79418.1 - 4.4e-64 214.7 5.0 4.4e-64 214.7 3.5 2.3 3 0 0 3 3 3 1 SKIP/SNW domain GBP PF02263.14 AFZ79419.1 - 6.9e-24 84.2 3.9 3.1e-14 52.6 0.0 4.4 4 0 0 4 4 4 3 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 AFZ79419.1 - 0.0078 16.1 0.1 0.046 13.6 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AFZ79419.1 - 0.011 15.6 0.8 0.14 11.9 0.6 2.8 2 1 0 2 2 2 0 Dynamin family DnaJ-X PF14308.1 AFZ79421.1 - 1.9e-44 151.4 1.5 2.6e-44 150.9 0.1 1.9 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 AFZ79421.1 - 6.4e-24 83.4 2.5 1.6e-23 82.1 1.7 1.7 1 0 0 1 1 1 1 DnaJ domain Glyco_tran_28_C PF04101.11 AFZ79422.1 - 6.3e-20 71.4 0.0 7.6e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 AFZ79422.1 - 0.0045 16.2 0.0 0.0052 16.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 LUC7 PF03194.10 AFZ79423.1 - 1.1e-62 211.8 5.0 2e-62 211.0 3.5 1.4 1 0 0 1 1 1 1 LUC7 N_terminus Viral_cys_rich PF08008.7 AFZ79423.1 - 0.045 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Viral cysteine rich DUF3027 PF11228.3 AFZ79423.1 - 0.073 12.7 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) DSHCT PF08148.7 AFZ79424.1 - 1.3e-53 180.8 0.0 2.6e-53 179.9 0.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.1 AFZ79424.1 - 1.5e-53 181.7 1.9 2.3e-53 181.1 1.3 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.24 AFZ79424.1 - 3.2e-22 78.8 0.0 1.2e-21 76.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ79424.1 - 4.6e-08 32.8 0.0 1.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ79424.1 - 0.0017 18.2 0.0 0.008 16.0 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 AFZ79424.1 - 0.045 12.9 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein CBM_21 PF03370.8 AFZ79425.1 - 0.005 16.7 0.4 0.012 15.6 0.3 1.7 1 1 0 1 1 1 1 Putative phosphatase regulatory subunit Gag_p24 PF00607.15 AFZ79425.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) FAINT PF04385.10 AFZ79427.1 - 2.6e-58 193.7 62.8 3.2e-05 23.6 0.0 16.2 16 0 0 16 16 16 14 Domain of unknown function, DUF529 PSP1 PF04468.7 AFZ79427.1 - 0.086 12.8 2.6 18 5.4 0.0 3.5 3 0 0 3 3 3 0 PSP1 C-terminal conserved region TruB-C_2 PF09157.6 AFZ79427.1 - 0.28 11.0 0.0 0.65 9.8 0.0 1.6 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal ABC_tran PF00005.22 AFZ79428.1 - 3e-27 95.5 0.0 8.4e-16 58.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 AFZ79428.1 - 2.9e-05 24.1 0.2 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.1 AFZ79428.1 - 0.00015 21.3 0.3 0.035 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AFZ79428.1 - 0.00049 19.5 1.1 0.28 10.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 AFZ79428.1 - 0.0019 19.0 0.0 0.69 10.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AFZ79428.1 - 0.0027 16.6 0.7 1.8 7.4 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein ArgK PF03308.11 AFZ79428.1 - 0.0031 16.3 0.8 0.0062 15.3 0.0 1.7 2 0 0 2 2 2 1 ArgK protein AAA_25 PF13481.1 AFZ79428.1 - 0.0048 16.3 0.0 0.23 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 AFZ79428.1 - 0.0055 16.1 0.1 1.2 8.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_21 PF13304.1 AFZ79428.1 - 0.013 15.4 5.3 0.56 10.1 0.0 4.4 5 0 0 5 5 4 0 AAA domain Miro PF08477.8 AFZ79428.1 - 0.013 15.9 0.1 8.4 6.9 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 AFZ79428.1 - 0.013 14.6 0.4 0.48 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 AFZ79428.1 - 0.014 15.7 0.1 1.5 9.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 AFZ79428.1 - 0.015 15.0 0.9 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 AFZ79428.1 - 0.015 15.4 0.1 10 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.13 AFZ79428.1 - 0.016 14.4 0.2 4.2 6.4 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ATP_bind_1 PF03029.12 AFZ79428.1 - 0.019 14.5 0.3 5 6.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 AFZ79428.1 - 0.029 14.6 3.4 4.8 7.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 AFZ79428.1 - 0.034 13.8 2.0 4.5 7.1 0.2 2.6 2 0 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 AFZ79428.1 - 0.039 13.0 0.3 9 5.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin UPF0079 PF02367.12 AFZ79428.1 - 0.06 12.9 1.0 0.72 9.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 AFZ79428.1 - 0.067 12.9 2.6 0.17 11.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 SMC_N PF02463.14 AFZ79428.1 - 0.11 11.6 1.0 0.85 8.8 0.1 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 AFZ79428.1 - 0.15 11.6 0.8 8 6.0 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 AFZ79428.1 - 0.24 11.2 0.4 6.7 6.5 0.1 2.8 3 0 0 3 3 2 0 AAA domain MAT1 PF06391.8 AFZ79431.1 - 3.2e-08 33.4 8.8 4.9e-08 32.7 6.1 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_3 PF13920.1 AFZ79431.1 - 0.0005 19.6 10.2 0.0013 18.3 7.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AFZ79431.1 - 0.0013 18.3 7.4 0.0041 16.7 5.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AFZ79431.1 - 0.0015 18.3 10.3 0.0015 18.3 7.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 AFZ79431.1 - 0.014 15.1 9.4 0.039 13.6 6.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain 4HB_MCP_1 PF12729.2 AFZ79431.1 - 0.047 13.0 2.4 0.072 12.4 1.7 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction PAPS_reduct PF01507.14 AFZ79431.1 - 0.092 12.5 0.6 0.17 11.6 0.3 1.5 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family zf-C3HC4_2 PF13923.1 AFZ79431.1 - 0.15 12.1 10.4 0.55 10.3 7.2 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rieske PF00355.21 AFZ79431.1 - 0.19 11.3 3.3 0.39 10.3 2.3 1.5 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain zf-RING_4 PF14570.1 AFZ79431.1 - 1.4 8.6 9.3 4.2 7.0 4.9 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 AFZ79431.1 - 1.7 8.6 7.7 15 5.5 5.4 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING C2 PF00168.25 AFZ79432.1 - 0.007 16.1 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 C2 domain Orbi_VP5 PF00901.12 AFZ79432.1 - 0.069 11.3 0.0 0.077 11.1 0.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 RecA PF00154.16 AFZ79433.1 - 0.076 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein IER PF05760.7 AFZ79433.1 - 2 8.2 8.1 3.5 7.4 5.6 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) C2 PF00168.25 AFZ79434.1 - 1.1e-13 50.8 0.0 5.2e-06 26.2 0.0 4.3 4 0 0 4 4 4 3 C2 domain ATG22 PF11700.3 AFZ79434.1 - 0.05 12.0 0.0 0.096 11.1 0.0 1.3 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like E1-E2_ATPase PF00122.15 AFZ79435.1 - 2.5e-63 213.2 4.2 2.5e-63 213.2 2.9 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AFZ79435.1 - 3.1e-45 153.9 2.5 3.1e-45 153.9 1.7 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AFZ79435.1 - 4.4e-30 105.6 0.4 8.8e-29 101.4 0.3 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AFZ79435.1 - 1e-17 63.8 0.1 2.3e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AFZ79435.1 - 4.3e-16 59.6 0.1 1.1e-15 58.3 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AFZ79435.1 - 2.8e-13 49.1 0.0 7.3e-13 47.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AFZ79435.1 - 0.0012 18.4 2.2 0.0042 16.6 0.9 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Clr2 PF10383.4 AFZ79435.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 TRM PF02005.11 AFZ79436.1 - 2.9e-98 329.2 0.1 6.1e-75 252.4 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_16 PF10294.4 AFZ79436.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Collagen PF01391.13 AFZ79438.1 - 2.4 7.7 26.6 2.6e+02 1.2 18.5 2.6 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) EVI2A PF05399.6 AFZ79440.1 - 0.33 10.1 1.9 0.41 9.8 1.3 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) UFD1 PF03152.9 AFZ79441.1 - 8.2e-72 240.0 0.0 1e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CHCH PF06747.8 AFZ79442.1 - 0.00073 19.3 7.9 0.00074 19.3 1.3 2.7 2 0 0 2 2 2 2 CHCH domain MCM PF00493.18 AFZ79443.1 - 1.1e-118 395.8 0.0 1.8e-118 395.1 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 AFZ79443.1 - 1.7e-13 50.8 28.8 1.7e-13 50.8 20.0 2.5 2 1 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 AFZ79443.1 - 4e-12 46.6 0.0 1.2e-11 45.1 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 AFZ79443.1 - 1.3e-07 30.9 0.1 6.4e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AFZ79443.1 - 0.00017 21.3 0.0 0.00043 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 AFZ79443.1 - 0.00022 20.7 0.0 0.68 9.3 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 AFZ79443.1 - 0.041 13.5 0.0 0.15 11.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 AFZ79443.1 - 0.081 12.9 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 AFZ79443.1 - 0.12 12.5 0.2 0.73 9.9 0.1 2.3 1 1 0 1 1 1 0 AAA domain DEK_C PF08766.6 AFZ79444.1 - 1.1e-06 28.2 0.2 2.1e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 DEK C terminal domain Cpn60_TCP1 PF00118.19 AFZ79444.1 - 0.055 12.0 1.1 0.064 11.8 0.8 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Vfa1 PF08432.5 AFZ79444.1 - 0.44 10.5 7.1 0.59 10.1 4.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ig_2 PF13895.1 AFZ79446.1 - 0.12 12.4 0.5 0.24 11.5 0.4 1.5 1 0 0 1 1 1 0 Immunoglobulin domain DUF1075 PF06388.6 AFZ79447.1 - 0.00038 20.1 0.1 0.00048 19.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) CHASE4 PF05228.8 AFZ79448.1 - 0.053 13.0 0.5 0.66 9.5 0.0 2.3 2 1 0 2 2 2 0 CHASE4 domain DUF3567 PF12091.3 AFZ79448.1 - 0.11 12.5 0.1 0.52 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) UBA_e1_C PF09358.5 AFZ79450.1 - 0.045 13.9 0.1 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain 5_3_exonuc_N PF02739.11 AFZ79453.1 - 1.2e-33 115.8 0.0 2.4e-25 88.8 0.0 2.3 2 0 0 2 2 2 2 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.15 AFZ79453.1 - 4.4e-19 68.5 0.0 8.4e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_lambd_f PF10391.4 AFZ79453.1 - 0.03 13.8 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HHH_2 PF12826.2 AFZ79453.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif LPAM_1 PF08139.7 AFZ79454.1 - 0.99 9.7 5.4 1.5 9.1 3.7 1.2 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site FAINT PF04385.10 AFZ79455.1 - 8.8e-48 160.0 35.4 7.4e-09 35.3 1.2 9.1 8 1 0 8 8 8 8 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79455.1 - 3.9e-09 36.3 41.0 0.00017 21.1 6.8 5.6 4 1 2 6 6 6 4 Merozoite Antigen WPP PF13943.1 AFZ79455.1 - 0.00067 19.8 1.2 0.38 10.9 0.0 3.7 3 0 0 3 3 3 2 WPP domain DUF2510 PF10708.4 AFZ79455.1 - 0.0037 16.6 2.4 8.1 5.9 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2510) Spt4 PF06093.8 AFZ79457.1 - 4.1e-06 26.5 0.0 4.5e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RSV_NS2 PF03113.9 AFZ79459.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 Sipho_Gp157 PF05565.6 AFZ79460.1 - 6.5 6.3 13.3 0.65 9.5 1.1 3.3 4 0 0 4 4 4 0 Siphovirus Gp157 Sel1 PF08238.7 AFZ79461.1 - 3.3e-19 68.8 8.3 2.9e-05 24.5 0.2 7.1 8 0 0 8 8 8 4 Sel1 repeat Pico_P2A PF00947.14 AFZ79462.1 - 0.018 14.8 0.3 0.052 13.3 0.2 1.7 1 0 0 1 1 1 0 Picornavirus core protein 2A Erf4 PF10256.4 AFZ79465.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family RVT_1 PF00078.22 AFZ79466.1 - 1.4e-34 119.3 0.1 2.5e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2846 PF11008.3 AFZ79467.1 - 0.037 13.8 0.0 3.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2846) FAINT PF04385.10 AFZ79467.1 - 0.13 12.1 0.3 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79468.1 - 1.6e-46 156.0 27.8 6.1e-07 29.2 0.1 9.7 9 0 0 9 9 9 9 Domain of unknown function, DUF529 Saf-Nte_pilin PF09460.5 AFZ79468.1 - 0.031 14.0 0.1 4.3 7.1 0.0 3.5 3 0 0 3 3 3 0 Saf-pilin pilus formation protein BING4CT PF08149.6 AFZ79468.1 - 0.048 13.1 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 BING4CT (NUC141) domain DUF4407 PF14362.1 AFZ79468.1 - 0.52 9.2 1.4 1.2 8.0 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAINT PF04385.10 AFZ79469.1 - 0.0001 22.0 0.0 0.00024 20.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function, DUF529 RRM_1 PF00076.17 AFZ79470.1 - 3e-15 55.5 0.0 5.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ79470.1 - 1.1e-12 47.7 0.0 1.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ79470.1 - 5.4e-09 35.7 0.0 8.7e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF91 PF01939.11 AFZ79471.1 - 0.046 12.8 0.1 0.074 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF91 TLV_coat PF00429.14 AFZ79471.1 - 0.14 10.5 2.0 0.25 9.7 1.4 1.4 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) NPV_P10 PF05531.7 AFZ79471.1 - 1.1 9.5 3.7 0.45 10.7 0.7 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein tRNA-synt_1 PF00133.17 AFZ79475.1 - 3.8e-91 305.9 0.1 9.4e-90 301.3 0.1 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AFZ79475.1 - 1.8e-14 53.8 2.9 4.3e-14 52.5 1.2 2.3 2 1 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AFZ79475.1 - 9.5e-11 40.9 2.6 1.4e-07 30.5 0.1 4.4 4 1 0 4 4 4 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 AFZ79475.1 - 0.016 14.4 0.1 0.042 13.1 0.1 1.7 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 FAINT PF04385.10 AFZ79476.1 - 2.8e-07 30.2 0.2 4.3e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 AFZ79477.1 - 1.4e-12 48.0 0.0 3.2e-12 46.8 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family FAINT PF04385.10 AFZ79477.1 - 9.1e-10 38.2 16.9 2.9e-05 23.8 0.2 4.8 3 2 2 5 5 5 3 Domain of unknown function, DUF529 Abhydrolase_5 PF12695.2 AFZ79477.1 - 1.3e-09 37.9 0.0 1e-08 35.0 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ79477.1 - 2.8e-06 27.0 0.3 4.2e-05 23.3 0.4 2.7 3 0 0 3 3 3 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 AFZ79477.1 - 0.014 15.0 0.0 0.04 13.4 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold U1snRNP70_N PF12220.3 AFZ79479.1 - 1.6e-23 82.8 3.8 2.3e-23 82.3 2.6 1.2 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 AFZ79479.1 - 2e-20 72.2 0.0 3.4e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ79479.1 - 3.6e-16 58.8 0.0 8e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ79479.1 - 4.3e-11 42.4 0.0 7.9e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_1 PF00175.16 AFZ79480.1 - 4.1e-11 43.4 0.0 7.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AFZ79480.1 - 3.7e-09 36.5 0.0 8.5e-08 32.2 0.0 2.2 1 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AFZ79480.1 - 2.1e-07 30.9 0.3 5.5e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Med22 PF06179.7 AFZ79481.1 - 0.049 13.6 0.0 0.057 13.4 0.0 1.1 1 0 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex FAINT PF04385.10 AFZ79484.1 - 3.5e-10 39.5 0.2 9.1e-09 35.0 0.0 2.6 2 1 1 3 3 3 1 Domain of unknown function, DUF529 Ras PF00071.17 AFZ79485.1 - 1.2e-10 40.9 0.0 2.2e-09 36.9 0.0 2.2 2 1 0 2 2 2 1 Ras family GTP_EFTU PF00009.22 AFZ79485.1 - 0.0014 18.0 0.0 0.0032 16.9 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TAFII55_N PF04658.8 AFZ79486.1 - 2.2e-26 92.2 0.0 4.4e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region Metallophos PF00149.23 AFZ79487.1 - 7.9e-16 58.0 1.1 7.9e-16 58.0 0.8 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DBR1 PF05011.8 AFZ79487.1 - 2.3e-14 53.5 0.1 6.1e-14 52.1 0.0 1.8 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos_2 PF12850.2 AFZ79487.1 - 8.7e-08 32.1 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SIP1 PF04938.7 AFZ79488.1 - 4.4e-05 22.9 0.2 0.0057 16.0 0.0 2.3 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF4208 PF13907.1 AFZ79488.1 - 0.1 12.8 0.3 5.6 7.2 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4208) BNIP3 PF06553.7 AFZ79488.1 - 0.12 11.7 0.9 0.2 11.0 0.6 1.3 1 0 0 1 1 1 0 BNIP3 Nop PF01798.13 AFZ79489.1 - 1.7e-55 186.4 0.7 2.8e-55 185.7 0.5 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 AFZ79489.1 - 2.4e-27 94.5 0.0 4.7e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 AFZ79489.1 - 2.7e-20 72.2 0.8 5.4e-20 71.3 0.6 1.5 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF3721 PF12518.3 AFZ79492.1 - 0.24 11.0 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function Sulfate_transp PF00916.15 AFZ79493.1 - 1.7e-23 83.0 14.8 1.7e-23 83.0 10.2 2.3 2 1 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 AFZ79493.1 - 3e-13 49.2 1.9 1.8e-12 46.7 1.3 2.4 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif Herpes_U55 PF06501.6 AFZ79493.1 - 0.00038 19.1 0.5 0.0006 18.4 0.3 1.2 1 0 0 1 1 1 1 Human herpesvirus U55 protein STAS PF01740.16 AFZ79493.1 - 0.00067 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain Glyco_hydro_108 PF05838.7 AFZ79493.1 - 0.1 12.7 0.1 0.96 9.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase 108 FAINT PF04385.10 AFZ79498.1 - 4e-19 68.2 16.8 1.6e-07 31.0 1.2 5.0 5 0 0 5 5 5 4 Domain of unknown function, DUF529 HdeA PF06411.6 AFZ79499.1 - 0.003 17.4 0.6 0.0067 16.3 0.0 1.8 2 0 0 2 2 2 1 HdeA/HdeB family gp37_C PF12604.3 AFZ79499.1 - 0.021 14.6 0.3 0.55 10.0 0.2 2.4 2 0 0 2 2 2 0 Tail fiber protein gp37 C terminal FAINT PF04385.10 AFZ79500.1 - 3.9e-09 36.2 0.0 6.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 OprF PF05736.6 AFZ79500.1 - 0.096 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 OprF membrane domain DUF2360 PF10152.4 AFZ79500.1 - 0.78 10.0 3.8 1.2 9.3 2.6 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) FAINT PF04385.10 AFZ79501.1 - 1.6e-12 47.1 0.0 0.0047 16.7 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79501.1 - 0.0055 16.2 0.1 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 AFZ79502.1 - 3.6e-12 45.9 3.1 2.7e-05 23.9 0.4 2.6 2 1 0 2 2 2 2 Domain of unknown function, DUF529 ApoA-II PF04711.8 AFZ79502.1 - 0.098 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) COX_ARM PF06481.9 AFZ79502.1 - 0.36 10.5 1.8 0.59 9.8 0.1 2.1 2 0 0 2 2 2 0 COX Aromatic Rich Motif DUF21 PF01595.15 AFZ79503.1 - 3.1e-34 117.8 1.3 4.6e-34 117.3 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 Profilin PF00235.14 AFZ79504.1 - 4.9e-08 33.1 0.1 5.5e-08 32.9 0.0 1.2 1 1 0 1 1 1 1 Profilin Nol1_Nop2_Fmu PF01189.12 AFZ79505.1 - 1.1e-86 290.7 0.0 1.4e-86 290.4 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 AFZ79505.1 - 6.4e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.11 AFZ79505.1 - 0.00036 20.1 0.0 0.0018 17.9 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein Fibrillarin PF01269.12 AFZ79505.1 - 0.00039 19.4 0.0 0.00068 18.6 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_26 PF13659.1 AFZ79505.1 - 0.0027 17.7 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AFZ79505.1 - 0.0027 17.2 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 AFZ79505.1 - 0.0041 16.7 0.1 0.0092 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Gly-zipper_OmpA PF13436.1 AFZ79506.1 - 7.8 6.1 4.5 16 5.1 3.1 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Ras PF00071.17 AFZ79508.1 - 1.5e-53 180.5 0.1 1.8e-53 180.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AFZ79508.1 - 9.1e-17 61.6 0.0 1.5e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AFZ79508.1 - 6.4e-13 48.3 0.1 7.5e-13 48.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AFZ79508.1 - 4.1e-07 29.6 0.0 5.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AFZ79508.1 - 9e-07 28.2 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DAP3 PF10236.4 AFZ79508.1 - 0.049 12.5 0.1 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 PduV-EutP PF10662.4 AFZ79508.1 - 0.15 11.5 0.2 6.6 6.2 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CDV3 PF15359.1 AFZ79509.1 - 0.1 12.6 7.0 0.18 11.8 4.9 1.4 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Proteasome PF00227.21 AFZ79510.1 - 4.4e-39 133.7 0.0 1.7e-20 73.1 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Rhomboid PF01694.17 AFZ79513.1 - 2.1e-20 73.2 22.8 2.8e-13 50.1 9.7 2.7 3 0 0 3 3 3 2 Rhomboid family UN_NPL4 PF11543.3 AFZ79514.1 - 1.5e-13 50.8 0.0 2.5e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 PB1 PF00564.19 AFZ79514.1 - 0.14 11.8 0.2 0.35 10.5 0.0 1.6 2 0 0 2 2 2 0 PB1 domain NPL4 PF05021.10 AFZ79517.1 - 9e-65 218.8 0.0 1.8e-64 217.8 0.0 1.5 1 1 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 AFZ79517.1 - 8.9e-07 28.6 0.1 2e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 NPL4 family, putative zinc binding region Ala_racemase_N PF01168.15 AFZ79519.1 - 2.4e-30 105.7 0.1 2.9e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Rhomboid PF01694.17 AFZ79520.1 - 7.2e-33 113.6 16.3 7.2e-33 113.6 11.3 1.9 3 0 0 3 3 3 1 Rhomboid family Ribosomal_L4 PF00573.17 AFZ79522.1 - 8.9e-44 149.1 0.7 8.9e-44 149.1 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 AFZ79522.1 - 0.0089 15.8 3.6 0.081 12.8 2.5 2.4 1 1 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain PIF1 PF05970.9 AFZ79522.1 - 0.054 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase CENP-T PF15511.1 AFZ79522.1 - 0.13 11.4 1.6 0.2 10.8 1.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T MORN PF02493.15 AFZ79523.1 - 1.7e-05 24.2 11.2 0.0004 19.9 1.0 3.5 3 0 0 3 3 3 2 MORN repeat NfeD PF01957.13 AFZ79524.1 - 0.54 10.3 4.8 0.19 11.8 0.2 2.4 1 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding HABP4_PAI-RBP1 PF04774.10 AFZ79525.1 - 2.3 8.7 7.4 5.1 7.6 5.0 1.9 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family FAINT PF04385.10 AFZ79526.1 - 2.3e-12 46.6 0.0 7.8e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Xpo1 PF08389.7 AFZ79527.1 - 1.4e-05 25.0 3.2 0.009 15.9 0.1 4.6 5 0 0 5 5 5 2 Exportin 1-like protein Trehalose_PPase PF02358.11 AFZ79527.1 - 0.017 14.0 0.0 0.055 12.3 0.0 1.7 2 0 0 2 2 2 0 Trehalose-phosphatase IBN_N PF03810.14 AFZ79528.1 - 0.0014 18.4 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF1454 PF07305.7 AFZ79529.1 - 0.038 13.0 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) COX16 PF14138.1 AFZ79530.1 - 0.039 14.1 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 A_deaminase_N PF08451.6 AFZ79531.1 - 0.078 13.0 0.6 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Adenosine/AMP deaminase N-terminal Guanylate_kin PF00625.16 AFZ79532.1 - 9.1e-47 158.8 0.0 1.1e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 AFZ79532.1 - 8.8e-06 26.0 0.2 0.00011 22.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AFZ79532.1 - 0.00014 21.7 0.0 0.0057 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AFZ79532.1 - 0.00051 20.8 0.1 0.0012 19.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AFZ79532.1 - 0.0012 19.0 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AFZ79532.1 - 0.0014 18.8 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AFZ79532.1 - 0.0017 18.2 0.0 0.0032 17.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 AFZ79532.1 - 0.0018 18.0 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 NTPase ADK PF00406.17 AFZ79532.1 - 0.0038 17.0 0.3 5.3 6.8 0.1 3.0 2 1 1 3 3 3 1 Adenylate kinase AAA_16 PF13191.1 AFZ79532.1 - 0.006 16.5 0.0 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 AFZ79532.1 - 0.0061 15.7 0.0 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NB-ARC PF00931.17 AFZ79532.1 - 0.011 14.6 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 AFZ79532.1 - 0.018 15.3 0.0 0.025 14.9 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 AFZ79532.1 - 0.022 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 AFZ79532.1 - 0.029 14.0 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 AFZ79532.1 - 0.03 14.0 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B EFP PF01132.15 AFZ79532.1 - 0.033 13.8 0.2 0.055 13.1 0.1 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain Arch_ATPase PF01637.13 AFZ79532.1 - 0.035 13.8 0.1 0.056 13.1 0.1 1.4 1 1 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 AFZ79532.1 - 0.048 13.8 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 AFZ79532.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain SRPRB PF09439.5 AFZ79532.1 - 0.069 12.3 0.0 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 AFZ79532.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region KTI12 PF08433.5 AFZ79532.1 - 0.11 11.6 0.0 0.45 9.6 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.16 AFZ79532.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PFK PF00365.15 AFZ79533.1 - 4.2e-34 117.7 0.0 2.7e-21 75.7 0.0 2.2 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.19 AFZ79533.1 - 0.065 12.6 0.1 0.17 11.2 0.1 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Glyco_hydro_1 PF00232.13 AFZ79534.1 - 0.033 12.3 0.1 0.065 11.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Pro_isomerase PF00160.16 AFZ79535.1 - 1.6e-46 158.3 0.1 3.3e-46 157.2 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 AFZ79535.1 - 2.6e-07 30.1 0.0 8.5e-07 28.4 0.0 1.8 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 AFZ79535.1 - 2.6e-05 23.6 1.4 0.0004 19.8 0.5 3.1 2 1 2 4 4 4 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 AFZ79535.1 - 8.6e-05 22.4 0.3 0.014 15.2 0.0 3.1 4 0 0 4 4 4 1 U-box domain DUF3524 PF12038.3 AFZ79536.1 - 0.047 13.2 0.1 0.095 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) CK_II_beta PF01214.13 AFZ79539.1 - 8.3e-64 214.4 0.0 1e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit zinc_ribbon_5 PF13719.1 AFZ79539.1 - 0.081 12.5 0.3 0.19 11.3 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AFZ79539.1 - 0.095 12.4 0.3 0.23 11.1 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain PseudoU_synth_2 PF00849.17 AFZ79541.1 - 0.025 14.4 0.0 0.033 14.0 0.0 1.4 1 1 0 1 1 1 0 RNA pseudouridylate synthase GerE PF00196.14 AFZ79541.1 - 0.099 11.9 0.3 13 5.1 0.0 3.0 4 0 0 4 4 4 0 Bacterial regulatory proteins, luxR family RNase_H2_suC PF08615.6 AFZ79542.1 - 8.8e-18 64.4 0.0 1.1e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Pkinase_C PF00433.19 AFZ79542.1 - 0.076 13.5 0.0 0.31 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein kinase C terminal domain TLD PF07534.11 AFZ79545.1 - 4.4e-32 110.9 2.5 9.1e-32 109.9 1.7 1.5 1 0 0 1 1 1 1 TLD PPP4R2 PF09184.6 AFZ79547.1 - 3.2e-11 43.3 0.2 4.8e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 PPP4R2 SMC_Nse1 PF07574.8 AFZ79549.1 - 0.022 14.3 1.0 0.028 14.0 0.7 1.1 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex YwqJ-deaminase PF14431.1 AFZ79549.1 - 0.074 12.9 0.0 0.52 10.1 0.0 2.1 1 1 1 2 2 2 0 YwqJ-like deaminase 7TMR-HDED PF07697.6 AFZ79549.1 - 0.078 12.6 0.4 0.099 12.3 0.3 1.2 1 1 0 1 1 1 0 7TM-HD extracellular DEAD_assoc PF08494.6 AFZ79549.1 - 0.086 12.5 0.0 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 DEAD/H associated Prp31_C PF09785.4 AFZ79550.1 - 2.9e-38 131.0 1.5 5e-38 130.3 1.1 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 AFZ79550.1 - 7.6e-28 96.7 1.1 3.9e-27 94.4 0.2 2.3 2 1 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 AFZ79550.1 - 8.5e-15 54.3 0.8 1.6e-14 53.4 0.5 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain ubiquitin PF00240.18 AFZ79551.1 - 5.7e-25 86.5 0.2 6.3e-25 86.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AFZ79551.1 - 2.9e-15 55.6 0.3 3.2e-15 55.5 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 AFZ79551.1 - 1.8e-06 27.8 0.1 4e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AFZ79551.1 - 0.00065 19.9 0.2 0.0023 18.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 AFZ79551.1 - 0.012 15.7 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 AFZ79551.1 - 0.021 14.7 0.1 0.21 11.5 0.0 2.0 1 1 1 2 2 2 0 GLUT4 regulating protein TUG YukD PF08817.5 AFZ79551.1 - 0.092 13.3 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Pro_isomerase PF00160.16 AFZ79552.1 - 8.3e-38 130.0 0.0 1.4e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_60s PF00428.14 AFZ79552.1 - 0.0023 18.2 5.7 0.0072 16.6 3.9 1.8 1 0 0 1 1 1 1 60s Acidic ribosomal protein Peptidase_C6 PF00851.13 AFZ79552.1 - 0.033 12.8 1.8 0.045 12.3 1.2 1.1 1 0 0 1 1 1 0 Helper component proteinase Phage_int_SAM_5 PF13102.1 AFZ79552.1 - 0.039 13.9 5.2 0.075 13.0 3.6 1.4 1 0 0 1 1 1 0 Phage integrase SAM-like domain DUF740 PF05340.7 AFZ79552.1 - 0.1 10.9 12.8 0.14 10.4 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF3408 PF11888.3 AFZ79552.1 - 0.22 11.4 8.1 0.35 10.8 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) LRR_4 PF12799.2 AFZ79553.1 - 9.4e-10 37.9 22.7 0.048 13.2 0.2 6.3 4 2 0 5 5 5 5 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.1 AFZ79553.1 - 6.1e-06 26.4 0.1 3.6e-05 23.9 0.0 2.4 3 0 0 3 3 3 1 Ubiquitin-like domain CAP_GLY PF01302.20 AFZ79553.1 - 1.2e-05 24.9 0.2 3.2e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.1 AFZ79553.1 - 9.9e-05 22.0 18.5 0.00023 20.8 0.7 4.5 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 AFZ79553.1 - 1.2 9.4 16.1 1.8 8.8 0.1 6.1 7 0 0 7 7 7 0 Leucine Rich Repeat PCNA_N PF00705.13 AFZ79554.1 - 1.3e-25 89.3 1.1 3.9e-25 87.8 0.3 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 AFZ79554.1 - 3.2e-20 72.3 0.2 8.6e-19 67.7 0.0 2.3 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 AFZ79554.1 - 7.3e-09 35.1 0.3 2.9e-08 33.1 0.2 1.8 1 1 0 1 1 1 1 Rad9 Thioredoxin PF00085.15 AFZ79557.1 - 3.6e-26 90.8 0.0 6.3e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AFZ79557.1 - 3.1e-07 30.5 0.4 1.9e-06 28.0 0.1 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AFZ79557.1 - 1.9e-06 27.8 0.2 0.0002 21.4 0.1 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.1 AFZ79557.1 - 0.00015 21.4 0.0 0.00059 19.5 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_7 PF13899.1 AFZ79557.1 - 0.00099 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.1 AFZ79557.1 - 0.01 15.6 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.1 AFZ79557.1 - 0.074 13.0 0.2 4.1 7.3 0.0 2.7 2 1 1 3 3 3 0 Thioredoxin AhpC-TSA PF00578.16 AFZ79557.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family MMR_HSR1 PF01926.18 AFZ79558.1 - 1.1e-08 35.0 1.5 2.1e-08 34.1 0.3 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AFZ79558.1 - 1.8e-05 24.2 4.3 0.0014 18.1 0.0 2.8 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 AFZ79558.1 - 0.00063 18.9 0.8 0.0043 16.2 0.6 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 AFZ79558.1 - 0.011 15.4 0.1 0.026 14.2 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 AFZ79558.1 - 0.02 15.1 0.1 0.063 13.5 0.1 1.8 1 0 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.7 AFZ79558.1 - 0.027 13.5 0.5 0.056 12.5 0.1 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 AFZ79558.1 - 0.045 13.2 0.1 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 AFZ79558.1 - 0.064 13.0 3.5 0.49 10.1 0.5 3.0 2 1 0 2 2 2 0 Dynamin family Arf PF00025.16 AFZ79558.1 - 0.07 12.3 0.9 1.2 8.3 0.0 2.4 1 1 1 2 2 2 0 ADP-ribosylation factor family cobW PF02492.14 AFZ79558.1 - 0.078 12.4 0.7 0.44 9.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 AFZ79558.1 - 0.1 12.9 0.4 0.1 12.9 0.3 2.4 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 AFZ79558.1 - 0.11 11.3 0.1 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FeoB_N PF02421.13 AFZ79558.1 - 0.14 11.4 1.3 0.24 10.6 0.1 2.0 3 0 0 3 3 3 0 Ferrous iron transport protein B PRCC PF10253.4 AFZ79559.1 - 4e-13 50.4 9.1 4e-13 50.4 6.3 2.6 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Abhydro_lipase PF04083.11 AFZ79559.1 - 0.1 11.9 0.0 0.29 10.5 0.0 1.8 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Mito_carr PF00153.22 AFZ79560.1 - 2.3e-55 184.2 5.5 9.1e-23 79.7 0.2 4.3 2 1 1 3 3 3 3 Mitochondrial carrier protein 14-3-3 PF00244.15 AFZ79562.1 - 1.4e-107 358.1 10.4 1.6e-107 357.9 7.2 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF3106 PF11304.3 AFZ79562.1 - 0.017 15.5 1.5 0.83 10.0 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) TnpB_IS66 PF05717.8 AFZ79563.1 - 0.15 11.4 0.1 24 4.4 0.0 2.7 2 1 1 3 3 3 0 IS66 Orf2 like protein Fcf1 PF04900.7 AFZ79564.1 - 4.7e-38 129.3 2.3 6.9e-38 128.8 1.6 1.3 1 0 0 1 1 1 1 Fcf1 PilI PF10623.4 AFZ79564.1 - 0.031 14.1 0.2 0.066 13.1 0.1 1.5 1 0 0 1 1 1 0 Plasmid conjugative transfer protein PilI MutS_IV PF05190.13 AFZ79565.1 - 1.1 9.5 5.3 3.2 8.0 0.3 2.6 2 0 0 2 2 2 0 MutS family domain IV DUF842 PF05811.8 AFZ79567.1 - 2.1e-27 95.1 13.5 2.6e-27 94.8 9.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) BBS2_C PF14782.1 AFZ79567.1 - 0.0027 16.3 0.1 0.0031 16.1 0.1 1.1 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal zf-Tim10_DDP PF02953.10 AFZ79567.1 - 0.0051 16.0 5.1 0.0051 16.0 3.6 2.3 1 1 1 2 2 2 1 Tim10/DDP family zinc finger FtsA PF14450.1 AFZ79567.1 - 0.0092 15.8 0.0 0.043 13.6 0.0 1.8 1 1 1 2 2 2 1 Cell division protein FtsA Histone PF00125.19 AFZ79568.1 - 1.4e-21 76.3 0.1 1.8e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AFZ79568.1 - 0.00017 21.5 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hairpins PF04877.7 AFZ79568.1 - 0.55 9.6 4.5 0.68 9.2 3.1 1.1 1 0 0 1 1 1 0 HrpZ TRAPP PF04051.11 AFZ79570.1 - 1.8e-16 60.0 0.1 2e-16 59.8 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DEAD PF00270.24 AFZ79572.1 - 5.3e-40 136.6 0.0 7.4e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ79572.1 - 1.4e-23 82.5 0.1 2.4e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 AFZ79573.1 - 2.2e-14 52.9 7.7 3.7e-14 52.2 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AFZ79573.1 - 1.3e-08 34.7 5.6 2.3e-08 33.9 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AFZ79573.1 - 7.3e-08 32.0 4.3 1.2e-07 31.3 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AFZ79573.1 - 4.1e-07 29.5 4.2 8e-07 28.6 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AFZ79573.1 - 6.1e-06 25.8 3.6 1.1e-05 24.9 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AFZ79573.1 - 2e-05 24.6 6.3 5.9e-05 23.1 4.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AFZ79573.1 - 0.0062 16.3 1.2 0.012 15.4 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 AFZ79573.1 - 0.012 15.2 2.1 0.032 13.9 1.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 AFZ79573.1 - 0.024 14.6 5.2 0.051 13.6 3.6 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 AFZ79573.1 - 0.075 13.0 3.4 0.19 11.6 2.3 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 AFZ79573.1 - 0.099 12.6 6.4 0.22 11.5 4.5 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 AFZ79573.1 - 0.11 12.1 4.0 0.25 11.0 2.8 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 AFZ79573.1 - 0.44 10.1 5.5 0.78 9.3 3.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 AFZ79573.1 - 0.84 9.4 7.2 0.57 9.9 3.3 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 TSP_1 PF00090.14 AFZ79574.1 - 5e-08 32.9 21.8 0.0016 18.5 1.9 4.9 4 0 0 4 4 4 3 Thrombospondin type 1 domain DUF1978 PF09321.5 AFZ79575.1 - 0.037 13.4 0.2 0.054 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Apolipoprotein PF01442.13 AFZ79575.1 - 0.044 13.2 0.1 0.075 12.5 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain FliD_C PF07195.7 AFZ79575.1 - 0.072 12.3 0.2 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus V_ATPase_I PF01496.14 AFZ79575.1 - 0.091 10.5 0.5 0.095 10.5 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Osmo_CC PF08946.5 AFZ79575.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.5 3 0 0 3 3 3 0 Osmosensory transporter coiled coil FAINT PF04385.10 AFZ79578.1 - 1.4e-10 40.8 18.7 7.5e-05 22.4 0.2 4.4 5 0 0 5 5 5 3 Domain of unknown function, DUF529 TSP_1 PF00090.14 AFZ79579.1 - 8e-06 25.8 32.8 0.00016 21.7 4.6 4.7 4 0 0 4 4 4 3 Thrombospondin type 1 domain DnaJ PF00226.26 AFZ79581.1 - 3.1e-29 100.4 1.3 5.6e-29 99.6 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AFZ79581.1 - 4.6e-28 96.9 0.7 3.1e-22 78.2 0.1 2.7 2 1 0 2 2 2 2 DnaJ C terminal domain ABM PF03992.11 AFZ79582.1 - 0.0087 16.0 0.3 0.015 15.3 0.2 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Abhydrolase_1 PF00561.15 AFZ79582.1 - 0.12 11.9 0.1 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold TrbM PF07424.6 AFZ79583.1 - 0.13 12.2 4.7 0.25 11.3 0.0 2.8 3 0 0 3 3 3 0 TrbM Leu_Phe_trans PF03588.9 AFZ79584.1 - 2.9e-30 104.6 0.0 4.5e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase TPK_catalytic PF04263.11 AFZ79585.1 - 0.022 14.3 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain UPF0139 PF03669.8 AFZ79585.1 - 0.076 12.5 0.3 0.34 10.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) s48_45 PF07422.8 AFZ79587.1 - 1e-21 77.1 2.1 7.6e-13 48.5 0.0 3.5 4 1 0 4 4 4 2 Sexual stage antigen s48/45 domain DinB PF05163.7 AFZ79589.1 - 0.25 11.0 2.3 0.47 10.1 1.1 1.8 2 0 0 2 2 2 0 DinB family DUF87 PF01935.12 AFZ79589.1 - 2.1 8.1 6.2 4.2 7.1 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 RP-C_C PF11800.3 AFZ79589.1 - 2.7 7.6 6.3 5 6.7 4.4 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Pkinase PF00069.20 AFZ79590.1 - 2.2e-31 108.9 0.0 3.7e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ79590.1 - 5.5e-10 38.7 0.0 9.3e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AFZ79590.1 - 1.7e-09 37.1 0.0 3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Tnp_zf-ribbon_2 PF13842.1 AFZ79590.1 - 0.21 12.0 3.8 1 9.7 0.3 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon FAINT PF04385.10 AFZ79593.1 - 9.4e-08 31.7 0.1 1.4e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79593.1 - 0.015 14.8 0.1 0.018 14.4 0.1 1.0 1 0 0 1 1 1 0 Merozoite Antigen DUF3155 PF11352.3 AFZ79593.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) KH_1 PF00013.24 AFZ79594.1 - 1.9e-05 24.2 0.9 4.7e-05 22.9 0.6 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 AFZ79594.1 - 0.0033 17.0 0.0 0.009 15.6 0.0 1.9 1 1 0 1 1 1 1 KH domain KH_4 PF13083.1 AFZ79594.1 - 0.0087 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 KH domain Mito_fiss_reg PF05308.6 AFZ79595.1 - 1.6 8.0 5.0 3.6 6.8 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator FAINT PF04385.10 AFZ79598.1 - 1.2e-08 34.6 0.1 0.005 16.6 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79599.1 - 3.5e-10 39.5 0.0 7.3e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79600.1 - 2e-06 27.5 0.0 3.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 SNARE PF05739.14 AFZ79601.1 - 4.3e-05 23.0 0.4 4.3e-05 23.0 0.3 2.0 2 0 0 2 2 2 1 SNARE domain EcoR124_C PF12008.3 AFZ79601.1 - 0.0018 17.5 3.7 0.0025 17.0 2.6 1.2 1 0 0 1 1 1 1 Type I restriction and modification enzyme - subunit R C terminal RRF PF01765.14 AFZ79601.1 - 0.047 13.1 2.8 0.083 12.3 1.2 1.9 1 1 1 2 2 2 0 Ribosome recycling factor Syntaxin-6_N PF09177.6 AFZ79601.1 - 0.057 13.8 5.1 0.69 10.3 0.2 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal UPF0180 PF03698.8 AFZ79601.1 - 0.071 12.9 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) ISG65-75 PF11727.3 AFZ79601.1 - 0.091 11.8 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF3482 PF11981.3 AFZ79601.1 - 0.11 11.6 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF2935 PF11155.3 AFZ79601.1 - 0.15 12.1 3.0 2.4 8.2 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF3571 PF12095.3 AFZ79601.1 - 0.22 11.7 1.3 5.5 7.2 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3571) TMF_TATA_bd PF12325.3 AFZ79601.1 - 0.23 11.2 8.1 1.7 8.3 0.2 2.5 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2408 PF10303.4 AFZ79601.1 - 0.31 11.1 4.4 0.26 11.3 1.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF148 PF02520.12 AFZ79601.1 - 0.4 10.4 7.8 1.8 8.3 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function DUF148 Cep57_CLD_2 PF14197.1 AFZ79601.1 - 0.69 9.8 4.1 3.6 7.5 0.5 2.5 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 NPV_P10 PF05531.7 AFZ79601.1 - 1.2 9.4 4.4 7.4 6.9 0.1 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 AFZ79601.1 - 1.5 8.9 5.8 1.4 9.0 0.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PAH PF02671.16 AFZ79601.1 - 2.4 7.8 6.1 34 4.1 4.2 2.5 1 1 0 1 1 1 0 Paired amphipathic helix repeat Ribosomal_L22 PF00237.14 AFZ79602.1 - 1.1e-15 57.4 0.3 2.6e-15 56.2 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Na_H_Exchanger PF00999.16 AFZ79603.1 - 1e-29 103.2 36.2 1.4e-29 102.8 25.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-met PF12874.2 AFZ79604.1 - 3.5e-06 27.0 1.5 6.5e-06 26.1 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 AFZ79604.1 - 0.021 14.4 0.1 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein GATase_5 PF13507.1 AFZ79604.1 - 0.056 12.3 0.0 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain zf-U1 PF06220.7 AFZ79604.1 - 0.13 11.8 0.3 0.24 10.9 0.2 1.4 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_jaz PF12171.3 AFZ79604.1 - 1.3 9.2 3.4 4.1 7.6 2.4 1.9 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF912 PF06024.7 AFZ79607.1 - 0.076 13.0 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3753 PF12575.3 AFZ79607.1 - 0.48 10.2 3.5 0.48 10.2 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) FAINT PF04385.10 AFZ79609.1 - 8.5e-23 80.0 20.9 1.2e-06 28.2 0.3 7.2 7 1 1 8 8 8 5 Domain of unknown function, DUF529 ChaB PF06150.7 AFZ79609.1 - 0.11 12.2 0.5 2.2 8.1 0.1 3.2 2 0 0 2 2 2 0 ChaB zf-C4_Topoisom PF01396.14 AFZ79609.1 - 0.25 10.8 2.4 1.6 8.2 0.1 2.6 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger ABC_tran PF00005.22 AFZ79610.1 - 6.3e-31 107.4 0.0 3e-15 56.7 0.0 2.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AFZ79610.1 - 1.4e-06 28.4 4.6 0.0033 17.4 0.2 3.5 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 AFZ79610.1 - 9e-06 25.1 1.4 0.1 12.1 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AFZ79610.1 - 1.6e-05 25.3 3.9 0.022 15.0 0.4 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 AFZ79610.1 - 7.5e-05 22.3 0.0 0.013 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 AFZ79610.1 - 0.00013 20.8 0.3 0.0022 16.8 0.0 2.1 2 0 0 2 2 2 1 ArgK protein AAA_25 PF13481.1 AFZ79610.1 - 0.00018 20.9 0.0 0.05 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AFZ79610.1 - 0.00021 21.3 0.1 0.26 11.2 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 AFZ79610.1 - 0.00026 20.1 0.6 0.27 10.4 0.2 2.5 2 1 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 AFZ79610.1 - 0.00027 21.7 0.3 0.27 12.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 AFZ79610.1 - 0.00028 21.1 0.1 1.5 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 AFZ79610.1 - 0.0006 18.9 0.1 1.1 8.3 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.13 AFZ79610.1 - 0.00077 18.9 0.2 0.5 9.8 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family SMC_N PF02463.14 AFZ79610.1 - 0.0012 18.1 0.9 0.034 13.3 0.1 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.18 AFZ79610.1 - 0.0013 18.5 0.4 0.17 11.7 0.0 2.7 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 AFZ79610.1 - 0.002 18.0 0.2 0.55 10.2 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.1 AFZ79610.1 - 0.0025 16.9 0.7 0.78 8.7 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain MobB PF03205.9 AFZ79610.1 - 0.0039 16.9 0.1 0.95 9.1 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 AFZ79610.1 - 0.0054 15.6 0.5 1.2 8.0 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.12 AFZ79610.1 - 0.0063 16.3 3.0 0.17 11.6 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_22 PF13401.1 AFZ79610.1 - 0.0081 16.2 0.0 4.3 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 AFZ79610.1 - 0.016 15.7 0.1 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Arch_ATPase PF01637.13 AFZ79610.1 - 0.017 14.8 0.0 7.7 6.1 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase TrwB_AAD_bind PF10412.4 AFZ79610.1 - 0.019 13.6 0.1 2.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SbcCD_C PF13558.1 AFZ79610.1 - 0.025 14.4 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 AFZ79610.1 - 0.033 13.6 0.3 1.1 8.6 0.0 2.6 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 AFZ79610.1 - 0.038 13.5 0.1 2.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 AFZ79610.1 - 0.039 12.9 0.0 4.1 6.3 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 AFZ79610.1 - 0.05 13.7 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 AFZ79610.1 - 0.06 12.1 0.2 0.39 9.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 AFZ79610.1 - 0.064 12.8 0.3 3.6 7.2 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 AFZ79610.1 - 0.067 12.8 0.1 10 5.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 AFZ79610.1 - 0.079 12.8 0.0 16 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AFZ79610.1 - 0.11 11.8 0.3 14 5.0 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 AFZ79610.1 - 0.12 11.2 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 AFZ79610.1 - 0.13 12.0 0.2 18 5.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain DnaB_C PF03796.10 AFZ79610.1 - 0.17 10.7 0.0 12 4.6 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_33 PF13671.1 AFZ79610.1 - 0.52 10.1 2.3 3.8 7.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain FAINT PF04385.10 AFZ79611.1 - 2.5e-09 36.8 6.8 0.0018 18.0 0.0 4.5 4 1 1 5 5 5 2 Domain of unknown function, DUF529 DUF4348 PF14254.1 AFZ79611.1 - 0.12 11.4 0.8 3.1 6.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4348) DnaJ PF00226.26 AFZ79612.1 - 3.9e-19 68.1 1.3 7.9e-19 67.1 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.15 AFZ79612.1 - 2.2e-07 30.5 0.1 6.3e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.1 AFZ79612.1 - 0.11 12.0 0.1 0.67 9.3 0.0 2.2 2 1 0 2 2 2 0 F plasmid transfer operon protein NTP_transferase PF00483.18 AFZ79613.1 - 3.5e-45 154.2 0.0 4.4e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 AFZ79613.1 - 6e-13 47.6 11.4 2.1e-06 26.9 2.3 3.6 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 AFZ79613.1 - 2.2e-11 44.1 0.0 3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.14 AFZ79613.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase Hexapep_2 PF14602.1 AFZ79613.1 - 2.4 7.7 11.1 0.15 11.6 1.3 3.3 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase UQ_con PF00179.21 AFZ79614.1 - 2.9e-23 81.8 0.1 3.8e-23 81.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AFZ79614.1 - 1.8e-05 24.5 0.0 2.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AFZ79614.1 - 0.001 18.9 0.1 0.0013 18.5 0.1 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_E PF14462.1 AFZ79614.1 - 0.0038 16.8 0.1 0.006 16.1 0.1 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family E UEV PF05743.8 AFZ79614.1 - 0.081 12.6 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 UEV domain MACPF PF01823.14 AFZ79616.1 - 7.9e-18 64.9 0.3 1.1e-17 64.4 0.2 1.1 1 0 0 1 1 1 1 MAC/Perforin domain Fil_haemagg_2 PF13332.1 AFZ79616.1 - 0.023 14.4 1.3 0.032 13.9 0.9 1.1 1 0 0 1 1 1 0 Haemagluttinin repeat Toxin_66 PF15544.1 AFZ79616.1 - 0.029 13.6 0.1 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative toxin 66 Adap_comp_sub PF00928.16 AFZ79617.1 - 1.1e-54 185.2 0.0 1.5e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AFZ79617.1 - 1.8e-05 24.4 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1279 PF06916.8 AFZ79621.1 - 6e-10 39.2 1.3 9.2e-10 38.6 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) Atg14 PF10186.4 AFZ79621.1 - 0.074 11.9 4.4 0.47 9.3 0.0 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PPR_2 PF13041.1 AFZ79622.1 - 0.12 12.3 0.0 0.84 9.6 0.0 2.1 2 0 0 2 2 2 0 PPR repeat family GHMP_kinases_N PF00288.21 AFZ79623.1 - 1.2e-05 25.3 1.8 2.1e-05 24.4 0.2 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain FAINT PF04385.10 AFZ79624.1 - 2.1e-13 49.9 14.2 4e-07 29.7 0.2 4.0 3 1 0 3 3 3 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 AFZ79624.1 - 1.9e-09 37.7 0.0 3.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ79624.1 - 1.3e-06 28.2 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ79624.1 - 4.4e-06 26.4 0.1 3.3e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase EMA PF02488.10 AFZ79624.1 - 0.0088 15.5 0.2 1.2 8.5 0.0 2.9 3 0 0 3 3 3 1 Merozoite Antigen FAINT PF04385.10 AFZ79625.1 - 1.4e-11 44.0 0.0 0.023 14.5 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function, DUF529 AAA_22 PF13401.1 AFZ79626.1 - 3.4e-09 36.9 0.2 1.2e-08 35.1 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 AFZ79626.1 - 1.3e-08 35.0 0.0 3.3e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 AFZ79626.1 - 1.3e-08 34.8 0.2 3.7e-08 33.3 0.1 1.8 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 AFZ79626.1 - 9e-07 29.1 0.2 3.4e-06 27.3 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 AFZ79626.1 - 3.4e-05 22.8 0.0 7.7e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.17 AFZ79626.1 - 0.003 16.4 0.7 0.0068 15.2 0.2 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.1 AFZ79626.1 - 0.0033 17.3 1.0 0.12 12.3 0.5 2.9 1 1 1 2 2 2 1 AAA domain PEPCK_ATP PF01293.15 AFZ79626.1 - 0.0057 15.2 0.2 0.011 14.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_19 PF13245.1 AFZ79626.1 - 0.0063 16.2 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain PIF1 PF05970.9 AFZ79626.1 - 0.0067 15.4 0.4 0.016 14.1 0.0 1.8 2 0 0 2 2 2 1 PIF1-like helicase AAA_10 PF12846.2 AFZ79626.1 - 0.019 14.3 0.4 0.037 13.4 0.1 1.6 2 0 0 2 2 2 0 AAA-like domain DUF2075 PF09848.4 AFZ79626.1 - 0.056 12.4 0.1 0.11 11.3 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CSTF2_hinge PF14327.1 AFZ79626.1 - 0.064 13.3 2.0 0.13 12.3 0.5 2.1 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 RNA_helicase PF00910.17 AFZ79626.1 - 0.11 12.6 0.5 2.7 8.2 0.0 3.0 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.1 AFZ79626.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_L28 PF00830.14 AFZ79627.1 - 4.1e-20 71.3 2.6 4.1e-20 71.3 1.8 2.3 3 0 0 3 3 3 1 Ribosomal L28 family ATP-synt_A PF00119.15 AFZ79628.1 - 0.0036 16.8 1.0 0.004 16.6 0.7 1.1 1 0 0 1 1 1 1 ATP synthase A chain DUF21 PF01595.15 AFZ79628.1 - 0.0058 15.9 0.7 0.0071 15.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF21 Pox_I5 PF04713.7 AFZ79628.1 - 1.2 8.9 5.1 0.37 10.5 0.7 2.2 2 1 0 2 2 2 0 Poxvirus protein I5 eIF-5_eIF-2B PF01873.12 AFZ79629.1 - 8.4e-36 122.3 0.1 1.3e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 PKI PF02827.11 AFZ79629.1 - 0.0027 17.7 2.8 0.0052 16.8 2.0 1.5 1 1 0 1 1 1 1 cAMP-dependent protein kinase inhibitor zf-RanBP PF00641.13 AFZ79629.1 - 0.049 12.7 1.8 3.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others CAF1 PF04857.15 AFZ79631.1 - 6.9e-64 215.7 2.2 9.7e-64 215.2 1.5 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.6 AFZ79631.1 - 4.7e-08 32.8 0.8 1e-07 31.7 0.5 1.6 1 0 0 1 1 1 1 RNA binding domain DNA_pol_A_exo1 PF01612.15 AFZ79631.1 - 9.4e-06 25.2 0.3 0.17 11.3 0.0 3.4 3 0 0 3 3 3 2 3'-5' exonuclease R3H PF01424.17 AFZ79631.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 0 R3H domain Spc97_Spc98 PF04130.8 AFZ79632.1 - 1.1e-57 195.5 14.3 1.2e-56 192.2 9.9 2.0 1 1 0 1 1 1 1 Spc97 / Spc98 family DUF842 PF05811.8 AFZ79632.1 - 0.034 13.6 0.4 0.11 12.0 0.3 1.8 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Sugar_tr PF00083.19 AFZ79633.1 - 5e-06 25.3 20.7 3.3e-05 22.6 14.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AFZ79634.1 - 5.2e-12 45.1 16.4 8.1e-12 44.5 11.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 AFZ79635.1 - 1.7e-11 43.4 9.6 1.7e-11 43.4 6.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily NdhL PF10716.4 AFZ79635.1 - 2.7 7.8 8.4 0.26 11.0 0.6 3.0 2 1 0 2 2 2 0 NADH dehydrogenase transmembrane subunit WD40 PF00400.27 AFZ79636.1 - 9.8e-08 31.6 0.6 0.0061 16.3 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat PX PF00787.19 AFZ79636.1 - 8.2e-07 28.8 0.3 1.8e-06 27.7 0.2 1.5 1 0 0 1 1 1 1 PX domain eIF-3c_N PF05470.7 AFZ79636.1 - 0.057 11.5 0.0 0.084 10.9 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_gyraseA_C PF03989.8 AFZ79636.1 - 0.07 12.4 0.1 0.78 9.0 0.0 2.5 2 1 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller ATPgrasp_Ter PF15632.1 AFZ79636.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon CAF1C_H4-bd PF12265.3 AFZ79637.1 - 6.4e-17 61.2 0.0 1.4e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 AFZ79637.1 - 1.3e-14 53.4 26.1 2.8e-05 23.8 1.8 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 AFZ79637.1 - 7.6e-05 22.5 0.2 0.015 15.0 0.0 3.2 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF1115 PF06544.7 AFZ79637.1 - 0.022 14.4 0.1 0.067 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) VPS9 PF02204.13 AFZ79638.1 - 4.1e-29 100.6 1.0 2.8e-28 97.9 0.1 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Acyltransferase PF01553.16 AFZ79639.1 - 1.1e-15 57.2 0.0 1.8e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase zf-CDGSH PF09360.5 AFZ79640.1 - 7.2e-22 76.9 10.3 2.3e-14 52.9 1.8 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type GcpE PF04551.9 AFZ79641.1 - 4.6e-158 525.7 0.0 8.1e-158 524.9 0.0 1.5 1 1 0 1 1 1 1 GcpE protein Citrate_synt PF00285.16 AFZ79642.1 - 3.5e-90 302.3 0.0 5e-90 301.7 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase Flavoprotein PF02441.14 AFZ79643.1 - 2.7e-40 137.0 0.0 5e-40 136.1 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein Snf7 PF03357.16 AFZ79643.1 - 1.8e-16 60.0 22.2 4.2e-16 58.8 15.4 1.6 1 1 0 1 1 1 1 Snf7 DUF939_C PF11728.3 AFZ79643.1 - 0.072 12.8 12.6 0.054 13.3 7.4 1.7 2 0 0 2 2 2 0 DUF939 C-terminal domain Pkinase PF00069.20 AFZ79644.1 - 7.7e-57 192.4 0.1 1.3e-44 152.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ79644.1 - 1.3e-30 106.3 0.0 1.5e-23 83.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AFZ79644.1 - 0.00021 20.3 0.0 0.00035 19.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 AFZ79644.1 - 0.078 12.3 0.2 4.7 6.4 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL WD40 PF00400.27 AFZ79645.1 - 6.7e-19 66.9 1.7 8.5e-05 22.2 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.1 AFZ79645.1 - 1.5e-05 24.5 0.3 0.035 13.5 0.0 3.0 2 2 1 3 3 3 2 PQQ-like domain CPSF_A PF03178.10 AFZ79645.1 - 0.00071 18.7 0.4 0.61 9.1 0.0 3.3 2 1 1 3 3 3 2 CPSF A subunit region PQQ_3 PF13570.1 AFZ79645.1 - 0.34 11.2 2.7 1.4e+02 2.9 0.0 4.9 6 1 0 6 6 6 0 PQQ-like domain WD40 PF00400.27 AFZ79646.1 - 1.6e-39 132.3 17.5 4.9e-07 29.3 0.0 9.8 10 0 0 10 10 10 7 WD domain, G-beta repeat Utp13 PF08625.6 AFZ79646.1 - 4.1e-24 84.8 0.0 7.8e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain BBS2_Mid PF14783.1 AFZ79646.1 - 9e-05 22.2 0.8 0.0095 15.7 0.0 3.7 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Apc4_WD40 PF12894.2 AFZ79646.1 - 0.00086 18.7 0.0 5.2 6.6 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 AFZ79647.1 - 4.1e-20 70.8 10.5 0.00014 21.6 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 AFZ79647.1 - 0.017 13.4 0.0 0.028 12.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Trep_Strep PF09605.5 AFZ79648.1 - 0.022 14.4 0.4 0.039 13.6 0.3 1.4 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) PP-binding_2 PF14573.1 AFZ79649.1 - 0.11 12.5 0.2 0.24 11.4 0.1 1.6 1 1 1 2 2 2 0 Acyl-carrier Abhydrolase_6 PF12697.2 AFZ79650.1 - 1.1e-28 100.7 0.0 1.8e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AFZ79650.1 - 1.4e-21 77.1 0.0 5.9e-21 75.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AFZ79650.1 - 1.5e-19 70.1 0.0 2.8e-18 66.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ79650.1 - 1.2e-06 28.2 0.1 3.1e-06 26.9 0.0 1.6 2 0 0 2 2 1 1 Putative lysophospholipase FSH1 PF03959.8 AFZ79650.1 - 1.2e-05 24.9 0.0 0.0018 17.7 0.0 3.0 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 AFZ79650.1 - 0.00062 19.0 0.0 0.6 9.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 AFZ79650.1 - 0.00089 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.6 AFZ79650.1 - 0.0019 17.9 0.0 0.051 13.2 0.0 2.2 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 AFZ79650.1 - 0.0076 15.5 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 AFZ79650.1 - 0.02 14.4 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2305 PF10230.4 AFZ79650.1 - 0.034 13.5 0.0 0.62 9.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 AFZ79650.1 - 0.11 11.9 0.0 0.77 9.1 0.0 2.2 2 1 0 2 2 2 0 Putative esterase Ndr PF03096.9 AFZ79650.1 - 0.15 10.5 0.0 0.37 9.2 0.0 1.6 1 1 0 1 1 1 0 Ndr family Ribosomal_L27 PF01016.14 AFZ79651.1 - 7.8e-11 41.6 0.2 8.3e-08 31.9 0.1 2.2 1 1 0 1 1 1 1 Ribosomal L27 protein FPL PF09758.4 AFZ79652.1 - 1.3e-48 164.5 0.7 3.2e-48 163.2 0.5 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3395 PF11875.3 AFZ79653.1 - 7.9e-22 77.5 0.0 1.8e-21 76.3 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 AFZ79653.1 - 1.7e-16 59.7 0.3 3.5e-16 58.6 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Kinesin PF00225.18 AFZ79654.1 - 3.8e-79 265.8 0.4 5.6e-79 265.2 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain CPL PF08144.6 AFZ79655.1 - 2e-05 24.4 0.3 0.0033 17.2 0.0 3.1 3 0 0 3 3 3 2 CPL (NUC119) domain Symplekin_C PF12295.3 AFZ79655.1 - 0.035 14.0 4.0 0.24 11.2 0.1 2.7 1 1 1 2 2 2 0 Symplekin tight junction protein C terminal DUF2637 PF10935.3 AFZ79656.1 - 1.4 8.7 9.0 1.1e+02 2.6 6.2 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2637) VKOR PF07884.9 AFZ79656.1 - 2.6 7.9 18.2 1.3 8.8 7.7 2.7 1 1 1 2 2 2 0 Vitamin K epoxide reductase family TatD_DNase PF01026.16 AFZ79657.1 - 1.8e-47 161.6 0.0 3.6e-47 160.7 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 AFZ79657.1 - 0.044 13.3 0.0 3.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase Vac14_Fig4_bd PF11916.3 AFZ79660.1 - 1.2e-45 154.9 4.1 2.1e-45 154.1 2.4 1.8 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 AFZ79660.1 - 5.3e-35 119.6 5.0 1.8e-31 108.3 0.3 3.6 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 AFZ79660.1 - 8.1e-06 25.4 0.0 0.45 10.7 0.0 4.3 3 0 0 3 3 3 2 HEAT repeat DUF3819 PF12842.2 AFZ79660.1 - 0.0027 17.4 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) Cnd1 PF12717.2 AFZ79660.1 - 0.013 15.3 16.1 0.29 10.9 0.4 4.4 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 AFZ79660.1 - 0.045 14.2 0.0 7.8 7.1 0.0 4.2 5 0 0 5 5 5 0 HEAT-like repeat ThiF PF00899.16 AFZ79661.1 - 2.8e-52 176.1 3.1 8.6e-34 116.2 0.0 2.7 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 AFZ79661.1 - 1.1e-34 119.2 0.0 6e-34 116.9 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 AFZ79661.1 - 1.1e-22 79.4 0.3 5.2e-22 77.1 0.2 2.1 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 AFZ79661.1 - 9.8e-22 76.0 1.5 1.9e-21 75.1 1.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site 2-Hacid_dh_C PF02826.14 AFZ79661.1 - 0.049 12.7 0.2 8.4 5.5 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 AFZ79661.1 - 0.054 13.9 0.4 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UPF0203 PF05254.7 AFZ79663.1 - 6e-16 58.0 6.5 7.1e-16 57.8 4.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 AFZ79663.1 - 0.021 14.5 4.9 0.057 13.2 3.4 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like YbfN PF13982.1 AFZ79663.1 - 0.029 14.5 0.4 0.39 10.9 0.0 2.0 1 1 1 2 2 2 0 YbfN-like lipoprotein UCR_hinge PF02320.11 AFZ79663.1 - 0.039 13.8 2.1 0.15 11.9 1.5 1.8 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.8 AFZ79663.1 - 0.055 13.4 4.3 1.5 8.9 2.8 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) FANCL_C PF11793.3 AFZ79663.1 - 0.067 13.1 3.0 2 8.4 0.4 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain DUF1903 PF08991.5 AFZ79663.1 - 0.17 12.0 4.6 0.2 11.8 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1903) Pet191_N PF10203.4 AFZ79663.1 - 0.42 10.6 4.0 9.8 6.3 0.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 AFZ79663.1 - 0.94 9.4 4.1 2.9 7.9 0.5 2.2 2 0 0 2 2 2 0 CHCH domain ADK PF00406.17 AFZ79664.1 - 1.5e-31 109.3 0.0 1.7e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 AFZ79664.1 - 6.1e-12 46.4 0.0 1e-11 45.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AFZ79664.1 - 3.5e-11 43.1 0.0 9.3e-11 41.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AFZ79664.1 - 2.1e-10 40.9 0.0 5.2e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AFZ79664.1 - 8.6e-10 38.0 0.0 1.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 AFZ79664.1 - 0.00052 20.1 0.0 0.0008 19.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 AFZ79664.1 - 0.00073 18.4 0.0 0.0013 17.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain CPT PF07931.7 AFZ79664.1 - 0.00077 19.1 0.0 0.00099 18.7 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_10 PF12846.2 AFZ79664.1 - 0.00081 18.9 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 AFZ79664.1 - 0.002 18.1 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 AFZ79664.1 - 0.0051 16.7 0.0 0.0072 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AFZ79664.1 - 0.0077 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 AFZ79664.1 - 0.016 14.6 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.18 AFZ79664.1 - 0.019 14.9 0.1 0.035 14.0 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.12 AFZ79664.1 - 0.024 14.0 0.0 2.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase ABC_tran PF00005.22 AFZ79664.1 - 0.024 14.9 0.0 0.045 14.0 0.0 1.5 2 0 0 2 2 1 0 ABC transporter NTPase_1 PF03266.10 AFZ79664.1 - 0.024 14.3 0.0 0.045 13.4 0.0 1.6 1 1 0 1 1 1 0 NTPase AAA_29 PF13555.1 AFZ79664.1 - 0.026 14.0 0.2 0.057 12.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.5 AFZ79664.1 - 0.028 13.6 0.1 0.1 11.8 0.0 1.9 2 1 0 2 2 2 0 Chromatin associated protein KTI12 NACHT PF05729.7 AFZ79664.1 - 0.038 13.6 0.0 0.079 12.6 0.0 1.7 1 1 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 AFZ79664.1 - 0.047 13.3 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 AFZ79664.1 - 0.048 12.8 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 AFZ79664.1 - 0.048 13.8 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 AFZ79664.1 - 0.052 12.3 0.0 0.089 11.5 0.0 1.5 1 1 0 1 1 1 0 ArgK protein RNA_helicase PF00910.17 AFZ79664.1 - 0.068 13.3 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 1 0 RNA helicase 6PF2K PF01591.13 AFZ79664.1 - 0.073 12.1 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MobB PF03205.9 AFZ79664.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 AFZ79664.1 - 0.082 12.3 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 AFZ79664.1 - 0.091 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.16 AFZ79664.1 - 0.092 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PRK PF00485.13 AFZ79664.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.1 AFZ79664.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain APS_kinase PF01583.15 AFZ79664.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase UPF0079 PF02367.12 AFZ79664.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 FAINT PF04385.10 AFZ79665.1 - 2e-08 33.9 0.1 3e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function, DUF529 RabGAP-TBC PF00566.13 AFZ79666.1 - 6.6e-48 163.0 0.2 1.1e-47 162.2 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IncA PF04156.9 AFZ79667.1 - 0.23 11.0 14.4 0.86 9.1 9.9 1.9 1 1 1 2 2 2 0 IncA protein DUF848 PF05852.6 AFZ79667.1 - 2 8.2 8.6 2.3 8.0 4.3 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Lge1 PF11488.3 AFZ79667.1 - 8.5 6.6 9.5 79 3.5 6.5 2.5 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 FBA PF04300.8 AFZ79669.1 - 0.077 12.9 1.4 1.3 8.9 0.0 2.7 3 1 1 4 4 4 0 F-box associated region IncA PF04156.9 AFZ79670.1 - 1 8.8 5.0 2 8.0 3.4 1.4 1 0 0 1 1 1 0 IncA protein Fez1 PF06818.10 AFZ79671.1 - 0.00094 19.2 10.0 0.00094 19.2 6.9 2.7 2 1 0 2 2 2 1 Fez1 Surfac_D-trimer PF09006.6 AFZ79671.1 - 0.15 11.8 0.8 0.7 9.6 0.1 2.5 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Cast PF10174.4 AFZ79671.1 - 0.34 8.9 43.2 0.24 9.4 15.5 2.2 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone DUF2937 PF11157.3 AFZ79671.1 - 2.7 7.3 6.6 0.6 9.4 1.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) Reo_sigmaC PF04582.7 AFZ79671.1 - 2.8 7.0 9.4 2.1 7.4 2.0 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Pkinase PF00069.20 AFZ79672.1 - 2.7e-59 200.4 0.0 4.2e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ79672.1 - 9.2e-27 93.7 0.0 1.4e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 AFZ79672.1 - 1.7e-12 47.2 0.4 0.00012 22.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AFZ79672.1 - 2.6e-11 41.9 2.8 2.7e-05 23.1 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 AFZ79672.1 - 1.2e-10 40.8 0.3 0.00016 21.2 0.4 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AFZ79672.1 - 1.9e-09 36.6 1.8 0.036 13.9 0.1 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 AFZ79672.1 - 0.00023 20.3 0.2 0.83 9.1 0.2 2.7 2 0 0 2 2 2 2 EF hand APH PF01636.18 AFZ79672.1 - 0.015 15.0 0.6 0.028 14.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family EF-hand_4 PF12763.2 AFZ79672.1 - 0.018 14.7 0.6 11 5.7 0.0 2.9 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 AFZ79672.1 - 0.037 13.6 0.4 0.097 12.3 0.3 1.7 1 0 0 1 1 1 0 EF hand Kdo PF06293.9 AFZ79672.1 - 0.074 12.1 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AFZ79672.1 - 0.091 11.7 0.1 0.61 8.9 0.1 2.0 1 1 0 1 1 1 0 Kinase-like Prismane PF03063.15 AFZ79672.1 - 0.15 10.4 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family BCAS2 PF05700.6 AFZ79673.1 - 1.9e-36 125.5 8.6 2.4e-36 125.3 6.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) KLRAQ PF10205.4 AFZ79673.1 - 0.14 12.1 3.9 0.2 11.7 1.9 1.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein UPF0121 PF03661.8 AFZ79674.1 - 3.1e-07 29.8 3.7 4.8e-07 29.2 2.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF2177 PF09945.4 AFZ79674.1 - 0.2 11.6 1.0 0.39 10.7 0.1 2.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2177) LSM PF01423.17 AFZ79675.1 - 7.6e-14 51.0 0.7 9e-14 50.7 0.5 1.1 1 0 0 1 1 1 1 LSM domain Sec23_trunk PF04811.10 AFZ79676.1 - 4.1e-59 199.8 0.0 6.1e-59 199.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AFZ79676.1 - 9e-31 105.3 1.1 2e-30 104.2 0.8 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 AFZ79676.1 - 1e-28 99.6 0.4 2.2e-28 98.6 0.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 AFZ79676.1 - 1.9e-13 49.6 3.0 5e-13 48.3 2.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 AFZ79676.1 - 6.1e-12 45.0 0.1 1.5e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.1 AFZ79676.1 - 0.00028 21.0 0.0 0.00086 19.4 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain CTP_transf_1 PF01148.15 AFZ79677.1 - 8.6e-09 35.4 26.2 1.8e-05 24.5 17.8 3.1 1 1 0 1 1 1 1 Cytidylyltransferase family FAINT PF04385.10 AFZ79680.1 - 1.3e-15 57.0 16.3 7.4e-07 28.9 2.9 3.5 3 0 0 3 3 3 3 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79681.1 - 2.1e-11 43.4 5.4 1.2e-05 25.0 1.4 3.7 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Actin PF00022.14 AFZ79682.1 - 5.3e-85 285.2 0.0 1.8e-84 283.4 0.0 1.7 1 1 0 1 1 1 1 Actin PP-binding PF00550.20 AFZ79683.1 - 4e-09 36.6 0.3 5.4e-09 36.1 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1493 PF07377.7 AFZ79683.1 - 0.0019 18.2 0.2 0.0023 18.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) PP-binding_2 PF14573.1 AFZ79683.1 - 0.0027 17.6 1.4 0.016 15.2 0.5 1.9 1 1 1 2 2 2 1 Acyl-carrier TYW3 PF02676.9 AFZ79683.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase TYW3 NGP1NT PF08153.7 AFZ79684.1 - 2.9e-38 130.7 2.3 6.4e-38 129.6 1.6 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 AFZ79684.1 - 1.2e-16 60.6 0.2 4.4e-14 52.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 AFZ79684.1 - 4.5e-06 26.0 0.0 0.0003 20.1 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 AFZ79684.1 - 0.00063 19.0 0.0 0.68 9.1 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 AFZ79684.1 - 0.00094 18.6 0.4 0.19 11.1 0.1 3.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 AFZ79684.1 - 0.0017 17.5 0.0 0.0054 15.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 AFZ79684.1 - 0.0032 17.2 0.8 0.86 9.4 0.0 3.2 2 1 1 3 3 3 1 Dynamin family MobB PF03205.9 AFZ79684.1 - 0.18 11.4 1.0 7.6 6.2 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B HPIH PF13323.1 AFZ79687.1 - 0.0074 16.0 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain with HPIH motif RRF PF01765.14 AFZ79688.1 - 7.1e-25 87.3 4.6 7.1e-25 87.3 3.2 2.0 1 1 1 2 2 2 1 Ribosome recycling factor Baculo_PEP_C PF04513.7 AFZ79688.1 - 0.22 11.3 2.4 13 5.5 0.4 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ALMT PF11744.3 AFZ79688.1 - 0.42 9.2 5.5 0.44 9.1 3.2 1.6 1 1 0 1 1 1 0 Aluminium activated malate transporter CRAL_TRIO_2 PF13716.1 AFZ79689.1 - 8.3e-10 38.7 0.1 9.9e-09 35.2 0.0 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Macro PF01661.16 AFZ79689.1 - 6.9e-06 25.9 0.1 1.7e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Macro domain PLATZ PF04640.9 AFZ79689.1 - 0.0066 16.6 0.8 0.018 15.2 0.6 1.6 1 0 0 1 1 1 1 PLATZ transcription factor RasGEF_N PF00618.15 AFZ79689.1 - 0.026 14.5 0.6 2 8.5 0.1 2.5 2 1 0 2 2 2 0 RasGEF N-terminal motif DUF866 PF05907.8 AFZ79690.1 - 5.7e-19 68.1 0.1 6.8e-19 67.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF1857 PF08982.6 AFZ79690.1 - 0.097 12.2 0.0 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1857) IP_trans PF02121.13 AFZ79691.1 - 3.3e-40 137.8 0.3 6.2e-40 136.9 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein PH PF00169.24 AFZ79691.1 - 6.5e-10 39.1 0.1 2.5e-09 37.2 0.0 2.1 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 AFZ79691.1 - 0.00068 19.7 0.0 0.0019 18.3 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain EF-hand_1 PF00036.27 AFZ79692.1 - 3.3e-40 132.3 9.8 9.9e-10 37.0 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 AFZ79692.1 - 2e-36 123.9 3.9 1.4e-19 69.9 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 AFZ79692.1 - 3.7e-35 119.2 9.0 6.1e-17 60.9 0.2 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 AFZ79692.1 - 6.9e-30 100.2 5.4 2.4e-09 36.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 AFZ79692.1 - 2.9e-29 99.0 7.8 3.6e-07 29.2 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 AFZ79692.1 - 1.1e-12 47.6 0.0 3.9e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 AFZ79692.1 - 6.1e-09 35.5 0.4 0.00028 20.5 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 AFZ79692.1 - 2.5e-08 33.9 0.1 0.00056 19.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 AFZ79692.1 - 4.8e-07 29.2 0.0 0.02 14.4 0.0 2.8 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 AFZ79692.1 - 5.8e-05 22.9 0.3 0.0012 18.7 0.0 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.8 AFZ79692.1 - 0.00072 19.1 0.1 0.28 10.7 0.0 2.6 2 1 1 3 3 3 1 Caleosin related protein DUF1103 PF06513.6 AFZ79692.1 - 0.0049 16.2 1.3 0.0053 16.1 0.9 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.8 AFZ79692.1 - 0.0054 16.4 0.0 1 9.0 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.11 AFZ79692.1 - 0.0065 16.4 0.6 3.2 7.7 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb4 LNS2 PF08235.8 AFZ79692.1 - 0.016 14.8 0.0 0.11 12.0 0.0 1.9 1 1 1 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) SusE PF14292.1 AFZ79692.1 - 0.032 14.0 0.3 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 SusE outer membrane protein DUF853 PF05872.7 AFZ79692.1 - 0.036 12.4 0.1 0.83 7.9 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) Toprim_2 PF13155.1 AFZ79692.1 - 0.049 13.9 0.2 7.4 6.9 0.0 2.4 2 1 0 2 2 2 0 Toprim-like MotA_activ PF09114.5 AFZ79692.1 - 0.081 12.6 0.2 9.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Fe_hyd_lg_C PF02906.9 AFZ79692.1 - 0.1 11.8 0.7 0.32 10.2 0.4 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF533 PF04391.7 AFZ79692.1 - 0.13 11.6 0.7 4.5 6.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF533) DUF1880 PF08976.6 AFZ79692.1 - 0.15 12.2 0.0 3.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) FAINT PF04385.10 AFZ79694.1 - 9.4e-11 41.4 2.8 0.00018 21.3 0.5 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79695.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function, DUF529 DUF3661 PF12400.3 AFZ79696.1 - 8.7e-26 90.5 7.0 3.4e-21 75.6 1.7 2.7 2 0 0 2 2 2 2 Vaculolar membrane protein Ribosomal_L22 PF00237.14 AFZ79697.1 - 2.3e-31 107.8 0.0 3.2e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e FAINT PF04385.10 AFZ79699.1 - 0.043 13.6 0.3 0.12 12.2 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79700.1 - 4.9e-14 51.9 0.2 1e-06 28.4 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 GATA PF00320.22 AFZ79700.1 - 0.0081 15.4 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 GATA zinc finger FAINT PF04385.10 AFZ79701.1 - 5e-19 67.9 14.0 3.3e-09 36.4 0.3 3.8 3 1 0 3 3 3 3 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79704.1 - 0.0072 16.1 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function, DUF529 IMCp PF12314.3 AFZ79706.1 - 6.5e-26 90.3 84.7 4.4e-22 78.0 27.3 5.2 1 1 3 4 4 4 3 Inner membrane complex protein FGGY_N PF00370.16 AFZ79707.1 - 3e-50 170.8 0.1 4.6e-50 170.2 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 AFZ79707.1 - 8.9e-45 152.7 0.0 1.6e-44 151.8 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Gly-zipper_OmpA PF13436.1 AFZ79708.1 - 0.015 14.9 1.2 0.037 13.6 0.8 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain YfmQ PF10787.4 AFZ79708.1 - 0.13 11.6 0.1 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group Pkinase PF00069.20 AFZ79710.1 - 1.7e-60 204.3 0.0 6e-60 202.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ79710.1 - 8e-33 113.5 0.0 2e-32 112.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AFZ79710.1 - 2.2e-05 23.5 0.0 3.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AFZ79710.1 - 0.0027 17.4 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AFZ79710.1 - 0.093 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAINT PF04385.10 AFZ79711.1 - 9.2e-05 22.2 0.0 0.026 14.3 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79712.1 - 7.1e-09 35.3 0.2 0.00014 21.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79713.1 - 4.6e-11 42.4 0.1 0.00038 20.2 0.0 2.9 2 1 2 4 4 4 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79713.1 - 0.0044 16.5 4.5 0.051 13.0 2.2 2.1 2 0 0 2 2 2 1 Merozoite Antigen IL4 PF00727.13 AFZ79713.1 - 0.028 14.2 0.6 0.62 9.9 0.2 2.2 2 0 0 2 2 2 0 Interleukin 4 Phytase-like PF13449.1 AFZ79713.1 - 0.056 12.6 0.1 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 Esterase-like activity of phytase FOLN PF09289.5 AFZ79713.1 - 0.12 12.2 1.8 0.13 12.1 0.3 1.9 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain TrpBP PF02081.10 AFZ79713.1 - 0.13 11.6 0.4 2.5 7.5 0.1 2.3 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein FAINT PF04385.10 AFZ79714.1 - 2.5e-09 36.8 3.1 1.5e-05 24.7 0.2 2.7 3 0 0 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79715.1 - 0.05 13.4 1.4 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function, DUF529 DUF3042 PF11240.3 AFZ79715.1 - 0.19 11.5 1.7 0.4 10.5 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) FAINT PF04385.10 AFZ79716.1 - 0.0071 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 DEAD PF00270.24 AFZ79717.1 - 1.5e-47 161.2 0.0 2.3e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ79717.1 - 2.6e-26 91.2 0.0 5.6e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ79717.1 - 3.1e-05 23.8 0.0 0.0001 22.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AFZ79717.1 - 0.018 15.2 0.6 0.12 12.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.9 AFZ79717.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain LSM PF01423.17 AFZ79718.1 - 3.6e-10 39.2 0.4 3.2e-08 32.9 0.0 2.6 2 0 0 2 2 2 2 LSM domain FHIPEP PF00771.15 AFZ79718.1 - 0.62 8.3 2.7 1.5 7.0 1.9 1.6 1 1 0 1 1 1 0 FHIPEP family Pox_D3 PF04580.8 AFZ79719.1 - 0.0077 15.4 0.4 0.016 14.4 0.3 1.4 1 0 0 1 1 1 1 Chordopoxvirinae D3 protein DUF3699 PF12480.3 AFZ79719.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3699) VSP PF03302.8 AFZ79719.1 - 0.19 10.3 0.1 0.29 9.7 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein VPS11_C PF12451.3 AFZ79720.1 - 0.0013 18.5 1.2 0.0034 17.1 0.8 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Abhydrolase_6 PF12697.2 AFZ79722.1 - 6.2e-13 49.1 0.0 1.4e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ79722.1 - 6.7e-12 45.3 0.0 1.7e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family FAINT PF04385.10 AFZ79722.1 - 1.6e-10 40.6 0.0 0.021 14.6 0.0 3.8 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Hydrolase_4 PF12146.3 AFZ79722.1 - 1.2e-07 31.4 0.6 4.5e-06 26.4 0.1 2.9 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 AFZ79722.1 - 0.00012 21.7 0.0 0.0018 17.8 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AFZ79722.1 - 0.0054 15.9 0.2 0.41 9.8 0.0 2.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 AFZ79722.1 - 0.031 13.8 0.1 0.3 10.5 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF900 PF05990.7 AFZ79722.1 - 0.095 12.0 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_2 PF02230.11 AFZ79722.1 - 0.16 11.4 0.3 0.54 9.6 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FAINT PF04385.10 AFZ79723.1 - 1.2e-09 37.8 0.0 0.044 13.6 0.0 3.3 3 0 0 3 3 3 3 Domain of unknown function, DUF529 XPG_N PF00752.12 AFZ79724.1 - 3.8e-07 30.2 0.2 7.2e-07 29.4 0.0 1.5 2 0 0 2 2 2 1 XPG N-terminal domain TrbE PF11100.3 AFZ79724.1 - 1.7 8.5 4.5 3 7.7 3.1 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TrbE TMEM154 PF15102.1 AFZ79725.1 - 0.051 13.2 0.1 0.15 11.7 0.0 1.8 1 1 0 1 1 1 0 TMEM154 protein family Glucos_trans_II PF14264.1 AFZ79725.1 - 0.053 12.5 5.9 0.086 11.8 4.1 1.2 1 0 0 1 1 1 0 Glucosyl transferase GtrII DUF1180 PF06679.7 AFZ79725.1 - 0.08 12.8 1.1 0.11 12.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) DUF998 PF06197.8 AFZ79725.1 - 0.26 10.5 0.6 0.38 10.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF4131 PF13567.1 AFZ79725.1 - 0.36 10.2 7.4 0.55 9.6 4.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2142 PF09913.4 AFZ79725.1 - 0.67 8.5 2.4 1.2 7.6 1.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) Wzy_C PF04932.10 AFZ79725.1 - 1.3 8.7 5.5 2.8 7.7 3.8 1.5 1 0 0 1 1 1 0 O-Antigen ligase DUF3290 PF11694.3 AFZ79725.1 - 1.8 8.2 5.7 4.2 7.1 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) FAINT PF04385.10 AFZ79726.1 - 1.7e-15 56.6 12.2 1.3e-05 24.8 0.3 4.6 3 3 2 5 5 5 3 Domain of unknown function, DUF529 Glyco_hydro_32N PF00251.15 AFZ79726.1 - 0.0016 17.9 0.3 0.0022 17.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Dishevelled PF02377.10 AFZ79726.1 - 0.086 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Dishevelled specific domain TcdB_toxin_midN PF12256.3 AFZ79726.1 - 0.1 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region Sugar_tr PF00083.19 AFZ79727.1 - 1.3e-59 201.9 33.4 1.6e-59 201.6 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AFZ79727.1 - 2e-11 43.2 35.8 2.3e-11 43.0 19.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AFZ79727.1 - 4.5e-05 21.8 2.2 4.5e-05 21.8 1.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FAINT PF04385.10 AFZ79728.1 - 1.3e-14 53.7 0.0 7.4e-09 35.3 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Hydrolase_3 PF08282.7 AFZ79729.1 - 9.6e-27 94.1 0.0 7.4e-26 91.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAINT PF04385.10 AFZ79729.1 - 0.0029 17.4 1.3 0.011 15.5 0.2 2.7 3 0 0 3 3 3 1 Domain of unknown function, DUF529 S6PP PF05116.8 AFZ79729.1 - 0.0064 15.8 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 AFZ79729.1 - 0.019 15.1 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Nop14 PF04147.7 AFZ79729.1 - 1.4 6.7 7.5 1.8 6.3 5.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 AFZ79729.1 - 5 6.3 5.6 6.8 5.8 3.9 1.1 1 0 0 1 1 1 0 SDA1 Peptidase_S24 PF00717.18 AFZ79730.1 - 0.058 13.0 0.5 0.13 11.9 0.4 1.6 1 1 0 1 1 1 0 Peptidase S24-like FAINT PF04385.10 AFZ79731.1 - 1.2e-15 57.1 1.0 1e-07 31.7 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF3530 PF12048.3 AFZ79731.1 - 1.5 7.7 4.8 0.17 10.8 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) IF4E PF01652.13 AFZ79733.1 - 7.8e-39 132.8 0.0 1.1e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E EMA PF02488.10 AFZ79735.1 - 1.4e-05 24.7 2.4 0.31 10.4 0.1 3.2 2 1 1 3 3 3 3 Merozoite Antigen FAINT PF04385.10 AFZ79735.1 - 4.2e-05 23.3 2.4 0.0042 16.8 0.3 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 RVT_1 PF00078.22 AFZ79737.1 - 1.1e-34 119.6 0.1 1.9e-34 118.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tn7_Tnp_TnsA_N PF08722.6 AFZ79738.1 - 0.099 12.6 2.1 2 8.4 1.5 2.4 1 1 0 1 1 1 0 TnsA endonuclease N terminal FAINT PF04385.10 AFZ79740.1 - 0.00042 20.1 0.2 0.001 18.8 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79741.1 - 0.0015 18.3 0.1 0.0048 16.7 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function, DUF529 Ank PF00023.25 AFZ79742.1 - 1e-27 94.5 2.1 4.3e-08 32.5 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 AFZ79742.1 - 2.7e-26 91.7 1.4 1.8e-17 63.4 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AFZ79742.1 - 6.8e-26 90.1 0.8 7.1e-12 45.5 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 AFZ79742.1 - 4e-20 71.3 0.1 3.8e-05 23.7 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AFZ79742.1 - 2.3e-18 64.4 1.6 0.00014 21.7 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat FAINT PF04385.10 AFZ79744.1 - 1.1e-21 76.4 21.3 5.7e-10 38.8 2.5 5.1 4 1 0 4 4 4 3 Domain of unknown function, DUF529 TPX2 PF06886.6 AFZ79744.1 - 0.059 13.4 1.2 0.9 9.6 0.1 2.6 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) FAINT PF04385.10 AFZ79745.1 - 2.5e-15 56.0 4.8 7.5e-07 28.9 0.0 4.1 4 0 0 4 4 4 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 AFZ79745.1 - 4.5e-14 52.8 0.0 1.5e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ79745.1 - 7e-11 42.0 0.0 1.7e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ79745.1 - 1.3e-09 37.7 0.1 2.4e-07 30.4 0.1 2.5 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 AFZ79745.1 - 0.0055 16.2 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 AFZ79745.1 - 0.018 14.4 0.1 2.2 7.6 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase UPF0565 PF10561.4 AFZ79745.1 - 0.037 12.9 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Abhydrolase_3 PF07859.8 AFZ79745.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold FAINT PF04385.10 AFZ79747.1 - 4.1e-41 138.6 41.8 2.9e-06 27.0 0.2 11.4 11 0 0 11 11 11 10 Domain of unknown function, DUF529 DUF500 PF04366.7 AFZ79749.1 - 0.03 13.7 0.0 0.035 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF500) FAINT PF04385.10 AFZ79750.1 - 0.094 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Hydrolase_3 PF08282.7 AFZ79752.1 - 6.4e-39 134.0 0.0 7.5e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AFZ79752.1 - 6.8e-06 25.5 0.0 0.013 14.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 AFZ79752.1 - 0.00047 20.3 0.2 0.0016 18.6 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AFZ79752.1 - 0.0023 18.3 0.0 0.031 14.6 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 AFZ79752.1 - 0.025 13.9 0.0 1 8.6 0.0 2.4 2 1 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_6 PF13344.1 AFZ79752.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FAINT PF04385.10 AFZ79754.1 - 5e-06 26.2 0.0 8.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79754.1 - 0.00092 18.7 0.3 0.0013 18.2 0.2 1.2 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 AFZ79756.1 - 9.6e-07 28.5 0.6 0.048 13.5 0.1 2.6 2 1 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79756.1 - 0.082 12.3 4.6 0.29 10.5 0.9 2.4 2 1 0 2 2 2 0 Merozoite Antigen FAINT PF04385.10 AFZ79757.1 - 5.6e-13 48.5 0.0 2.1e-05 24.2 0.0 3.7 3 0 0 3 3 3 3 Domain of unknown function, DUF529 ABC_tran PF00005.22 AFZ79758.1 - 1.8e-35 122.2 0.0 3.6e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 AFZ79758.1 - 1.8e-23 83.3 10.5 2.6e-23 82.8 7.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 AFZ79758.1 - 2.9e-09 36.4 0.8 3.4e-07 29.7 0.6 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 AFZ79758.1 - 3.9e-07 30.9 0.2 1.5e-06 29.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 AFZ79758.1 - 2.2e-06 27.4 0.8 9.1e-05 22.2 0.6 2.3 1 1 0 1 1 1 1 NTPase AAA_21 PF13304.1 AFZ79758.1 - 2e-05 24.7 0.1 0.0011 19.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AFZ79758.1 - 5.5e-05 23.4 0.1 0.00018 21.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AFZ79758.1 - 9.8e-05 22.5 0.2 0.00045 20.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 AFZ79758.1 - 0.00012 22.2 0.3 0.0027 17.8 0.2 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AFZ79758.1 - 0.00013 21.9 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DEAD PF00270.24 AFZ79758.1 - 0.0011 18.5 0.1 0.0028 17.1 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase MobB PF03205.9 AFZ79758.1 - 0.0012 18.5 0.8 0.0034 17.0 0.1 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 AFZ79758.1 - 0.0029 17.4 0.1 0.0081 16.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_19 PF13245.1 AFZ79758.1 - 0.0029 17.3 0.0 0.0075 16.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_23 PF13476.1 AFZ79758.1 - 0.005 17.1 2.3 0.005 17.1 1.6 1.9 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 AFZ79758.1 - 0.0098 15.7 0.6 0.19 11.6 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AFZ79758.1 - 0.011 15.1 0.1 0.04 13.4 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 AFZ79758.1 - 0.012 15.1 0.0 0.054 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 AFZ79758.1 - 0.016 14.9 0.1 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ResIII PF04851.10 AFZ79758.1 - 0.022 14.6 0.1 0.072 12.9 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit YebG PF07130.7 AFZ79758.1 - 0.027 14.1 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 YebG protein RNA_helicase PF00910.17 AFZ79758.1 - 0.057 13.6 0.0 0.57 10.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DUF258 PF03193.11 AFZ79758.1 - 0.057 12.6 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MSC PF09402.5 AFZ79758.1 - 0.059 12.0 0.1 0.13 10.9 0.1 1.5 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain FtsK_SpoIIIE PF01580.13 AFZ79758.1 - 0.071 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 AFZ79758.1 - 0.072 12.5 0.0 0.16 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 AFZ79758.1 - 0.074 12.9 0.4 0.4 10.5 0.3 2.3 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AFZ79758.1 - 0.095 11.7 0.0 0.23 10.5 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin WBP-1 PF11669.3 AFZ79758.1 - 0.16 12.0 0.1 0.16 12.0 0.1 2.7 2 1 2 4 4 3 0 WW domain-binding protein 1 FAINT PF04385.10 AFZ79760.1 - 0.00047 19.9 0.1 0.00083 19.1 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function, DUF529 WD40 PF00400.27 AFZ79761.1 - 2.9e-41 137.8 20.0 4.2e-09 35.9 0.0 8.9 9 0 0 9 9 9 7 WD domain, G-beta repeat Nup160 PF11715.3 AFZ79761.1 - 1.7e-05 23.1 4.6 0.14 10.2 0.4 4.0 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Herpes_UL25 PF01499.11 AFZ79761.1 - 0.26 9.5 1.3 0.46 8.7 0.9 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family FlaF PF07309.6 AFZ79762.1 - 0.4 10.5 2.6 0.32 10.8 0.7 1.7 2 0 0 2 2 2 0 Flagellar protein FlaF DUF2422 PF10337.4 AFZ79763.1 - 0.41 9.3 2.7 0.6 8.8 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) V_ATPase_I PF01496.14 AFZ79763.1 - 7.4 4.2 16.9 1.2 6.8 8.0 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family PIG-H PF10181.4 AFZ79766.1 - 1.5e-12 46.9 2.9 5.7e-12 45.0 0.7 2.1 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component FAINT PF04385.10 AFZ79770.1 - 1.5e-27 95.1 6.8 2.4e-05 24.0 0.2 5.7 5 0 0 5 5 5 5 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79771.1 - 6.9e-20 70.6 18.2 7.9e-07 28.8 0.2 4.3 4 0 0 4 4 4 4 Domain of unknown function, DUF529 Glycos_transf_2 PF00535.21 AFZ79772.1 - 3.9e-24 85.2 0.0 8.3e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 AFZ79772.1 - 7.6e-07 28.5 0.0 1.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 AFZ79772.1 - 3.2e-06 27.1 0.0 6.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 AFZ79772.1 - 0.0003 19.9 0.0 0.00049 19.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 OTU PF02338.14 AFZ79773.1 - 1e-23 84.2 0.7 1e-23 84.2 0.5 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 AFZ79773.1 - 4.4e-05 22.9 0.2 0.043 13.1 0.0 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain PHD PF00628.24 AFZ79774.1 - 3.2e-06 26.7 7.1 7.4e-06 25.5 4.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.1 AFZ79774.1 - 0.0013 18.7 1.3 0.0031 17.5 0.9 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD_2 PF13831.1 AFZ79774.1 - 0.0079 15.4 3.7 0.0079 15.4 2.5 2.0 2 1 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.1 AFZ79774.1 - 0.0093 16.0 0.4 0.027 14.5 0.3 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-PHD-like PF15446.1 AFZ79774.1 - 0.015 14.5 1.8 0.015 14.5 1.3 1.7 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 AFZ79774.1 - 0.034 13.8 2.1 0.034 13.8 1.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 AFZ79774.1 - 0.05 13.6 4.4 0.11 12.5 3.0 1.6 1 0 0 1 1 1 0 RING-like domain zf-RING_2 PF13639.1 AFZ79774.1 - 0.073 12.9 5.1 0.17 11.7 3.5 1.7 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.17 AFZ79774.1 - 0.12 12.1 9.8 0.036 13.7 1.9 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Methyltransf_16 PF10294.4 AFZ79775.1 - 2.2e-26 92.3 0.0 5.5e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Ank_5 PF13857.1 AFZ79775.1 - 1.6e-12 47.2 0.4 0.0043 17.2 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 AFZ79775.1 - 1.8e-12 47.4 0.3 8.8e-10 38.7 0.2 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AFZ79775.1 - 2.5e-08 34.2 0.1 0.00036 20.9 0.1 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 AFZ79775.1 - 4.7e-08 32.5 0.2 0.0038 17.3 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 AFZ79775.1 - 3.4e-07 29.7 0.0 0.00023 20.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Methyltransf_18 PF12847.2 AFZ79775.1 - 0.012 16.1 0.0 0.06 13.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 AFZ79775.1 - 0.016 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DUF1344 PF07076.6 AFZ79777.1 - 0.099 12.2 0.1 5.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) HALZ PF02183.13 AFZ79778.1 - 0.00034 20.2 2.0 0.00034 20.2 1.4 2.6 2 0 0 2 2 2 1 Homeobox associated leucine zipper Ribosomal_60s PF00428.14 AFZ79778.1 - 0.43 11.0 5.3 0.18 12.2 1.4 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Shugoshin_N PF07558.6 AFZ79778.1 - 0.53 10.0 7.2 0.88 9.3 0.6 3.3 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region UPF0449 PF15136.1 AFZ79778.1 - 0.68 10.1 4.6 0.27 11.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 OmpH PF03938.9 AFZ79778.1 - 1.9 8.3 6.9 4.1 7.3 0.5 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DivIC PF04977.10 AFZ79778.1 - 2.8 7.5 9.4 0.051 13.0 0.9 2.4 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 AFZ79778.1 - 3.1 7.3 6.2 0.37 10.3 0.4 2.1 2 0 0 2 2 2 0 IncA protein YPEB PF14620.1 AFZ79779.1 - 0.025 13.5 1.7 0.034 13.1 1.1 1.1 1 0 0 1 1 1 0 YpeB sporulation DUF4600 PF15372.1 AFZ79779.1 - 0.26 11.5 4.1 0.51 10.5 2.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) zf-C4H2 PF10146.4 AFZ79779.1 - 4.5 7.2 7.4 7.2 6.5 5.1 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein FlaC_arch PF05377.6 AFZ79779.1 - 6.7 6.6 7.9 10 6.1 0.7 3.7 3 2 0 3 3 3 0 Flagella accessory protein C (FlaC) P12 PF12669.2 AFZ79781.1 - 0.013 15.6 0.2 0.04 14.1 0.1 1.8 1 0 0 1 1 1 0 Virus attachment protein p12 family tRNA-synt_2 PF00152.15 AFZ79783.1 - 3.5e-69 233.1 0.0 2.1e-68 230.5 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AFZ79783.1 - 5.8e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AFZ79783.1 - 0.0038 16.4 0.1 0.029 13.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Pox_L3_FP4 PF03339.9 AFZ79785.1 - 0.35 9.2 2.2 0.28 9.6 0.2 1.6 2 0 0 2 2 2 0 Poxvirus L3/FP4 protein GAF PF01590.21 AFZ79786.1 - 1.2e-16 61.2 0.2 5.6e-14 52.5 0.1 2.9 2 1 1 3 3 3 2 GAF domain GAF_2 PF13185.1 AFZ79786.1 - 1.7e-12 48.0 0.0 4.5e-09 36.9 0.0 2.7 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.1 AFZ79786.1 - 2.7e-12 46.8 0.0 1.4e-08 34.9 0.0 2.4 2 0 0 2 2 2 2 GAF domain CPSF_A PF03178.10 AFZ79787.1 - 1.1e-22 80.6 1.2 2.5e-17 62.9 0.0 3.5 5 0 0 5 5 5 2 CPSF A subunit region ANAPC15 PF15243.1 AFZ79789.1 - 0.28 11.2 5.2 0.37 10.8 3.6 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 FAINT PF04385.10 AFZ79790.1 - 5.8e-13 48.4 5.8 0.0017 18.1 0.0 5.9 5 1 0 5 5 5 4 Domain of unknown function, DUF529 eRF1_2 PF03464.10 AFZ79791.1 - 1.7e-44 151.3 0.0 3.2e-44 150.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 AFZ79791.1 - 2e-33 115.0 0.2 4.1e-33 114.0 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 AFZ79791.1 - 2.3e-26 91.9 0.0 4.4e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 AFZ79791.1 - 0.058 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HSP70 PF00012.15 AFZ79794.1 - 4.2e-266 883.6 10.2 4.8e-266 883.4 7.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AFZ79794.1 - 5.4e-18 64.6 3.3 8.7e-17 60.6 0.4 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 AFZ79794.1 - 1.2e-06 28.4 0.6 0.89 9.3 0.0 4.1 3 1 0 3 3 3 3 Cell division protein FtsA FGGY_C PF02782.11 AFZ79794.1 - 7.2e-05 22.4 0.1 0.00022 20.9 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Ribosomal_S14 PF00253.16 AFZ79797.1 - 0.0018 17.5 0.8 0.0018 17.5 0.5 2.3 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e SepZ PF06066.6 AFZ79797.1 - 0.015 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 SepZ FAINT PF04385.10 AFZ79800.1 - 1.8e-14 53.3 0.6 9.6e-06 25.3 0.0 4.1 4 0 0 4 4 4 3 Domain of unknown function, DUF529 2-Hacid_dh_C PF02826.14 AFZ79800.1 - 0.11 11.6 0.0 3 6.9 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAINT PF04385.10 AFZ79802.1 - 1.6e-05 24.6 0.9 2.8e-05 23.8 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79803.1 - 0.11 12.3 10.7 0.63 9.9 0.4 3.6 2 1 1 3 3 3 0 Domain of unknown function, DUF529 Cys_rich_CPXG PF14255.1 AFZ79804.1 - 0.51 10.1 5.3 0.97 9.3 0.4 2.7 2 0 0 2 2 2 0 Cysteine-rich CPXCG FAINT PF04385.10 AFZ79805.1 - 3.5e-08 33.1 5.3 0.034 13.9 0.1 3.7 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79805.1 - 0.00038 20.0 1.5 0.022 14.2 0.1 3.0 3 0 0 3 3 3 1 Merozoite Antigen GP41 PF00517.12 AFZ79805.1 - 0.61 9.6 6.2 0.37 10.3 0.4 2.1 2 0 0 2 2 2 0 Retroviral envelope protein Daxx PF03344.10 AFZ79806.1 - 0.032 12.7 14.0 0.049 12.1 9.7 1.3 1 0 0 1 1 1 0 Daxx Family COMP PF11598.3 AFZ79806.1 - 0.31 11.1 2.4 32 4.6 0.1 3.2 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein Trypan_PARP PF05887.6 AFZ79806.1 - 1.2 8.9 9.4 2.8 7.7 6.5 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NOA36 PF06524.7 AFZ79806.1 - 2.5 7.2 12.2 4.5 6.4 8.5 1.3 1 0 0 1 1 1 0 NOA36 protein FAINT PF04385.10 AFZ79808.1 - 1.2e-50 169.2 35.4 6.5e-06 25.9 0.0 10.6 10 0 0 10 10 10 10 Domain of unknown function, DUF529 BBS2_N PF14781.1 AFZ79812.1 - 0.036 13.6 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal MAP2_projctn PF08377.5 AFZ79812.1 - 0.045 11.3 0.2 0.047 11.2 0.1 1.0 1 0 0 1 1 1 0 MAP2/Tau projection domain FAINT PF04385.10 AFZ79813.1 - 0.00024 20.8 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79814.1 - 1.9e-05 24.3 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Sigma70_ner PF04546.8 AFZ79815.1 - 0.15 11.6 2.8 0.25 10.9 2.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region WBP-1 PF11669.3 AFZ79817.1 - 2.4 8.2 9.8 4.9 7.2 6.8 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 RNA_pol_A_bac PF01000.21 AFZ79819.1 - 3.8e-23 81.7 0.0 8e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AFZ79819.1 - 1.6e-15 55.9 0.0 2.3e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Spore-coat_CotZ PF10612.4 AFZ79819.1 - 0.01 15.7 1.5 0.02 14.7 1.0 1.4 1 0 0 1 1 1 0 Spore coat protein Z Fer4_10 PF13237.1 AFZ79819.1 - 0.14 12.0 4.3 0.26 11.1 3.0 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 AFZ79819.1 - 0.26 11.5 4.6 0.76 10.0 3.2 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain EMA PF02488.10 AFZ79820.1 - 0.0027 17.2 0.0 0.0031 17.0 0.0 1.0 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 AFZ79820.1 - 0.017 14.9 0.1 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, DUF529 DUF2718 PF10918.3 AFZ79820.1 - 0.037 14.0 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) FAINT PF04385.10 AFZ79821.1 - 1.2e-16 60.2 16.6 2.7e-06 27.1 0.0 4.3 5 0 0 5 5 5 3 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79822.1 - 1.7e-20 72.6 0.4 2.6e-11 43.2 1.5 2.2 2 0 0 2 2 2 2 Domain of unknown function, DUF529 BRX_N PF13713.1 AFZ79823.1 - 0.011 15.1 0.8 0.033 13.6 0.2 2.0 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain TF_Zn_Ribbon PF08271.7 AFZ79823.1 - 0.17 11.2 0.9 0.37 10.1 0.7 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Lipoprotein_21 PF14041.1 AFZ79824.1 - 0.0053 16.6 0.1 0.016 15.1 0.1 1.8 1 0 0 1 1 1 1 LppP/LprE lipoprotein eIF-1a PF01176.14 AFZ79825.1 - 8e-29 98.8 0.1 1.1e-28 98.3 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PCI PF01399.22 AFZ79826.1 - 1.5e-15 57.3 0.1 1.9e-14 53.8 0.0 2.6 2 1 0 2 2 2 1 PCI domain MecA PF05389.7 AFZ79826.1 - 0.041 13.4 0.3 0.041 13.4 0.2 2.4 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) DUF1949 PF09186.6 AFZ79826.1 - 0.099 12.2 0.6 3.2 7.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1949) Cys_rich_CPXG PF14255.1 AFZ79827.1 - 0.11 12.3 0.3 0.26 11.1 0.2 1.7 1 0 0 1 1 1 0 Cysteine-rich CPXCG Snapin_Pallidin PF14712.1 AFZ79827.1 - 0.72 10.2 3.8 0.34 11.2 1.0 1.7 2 0 0 2 2 2 0 Snapin/Pallidin DUF2544 PF11245.3 AFZ79829.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2544) Brr6_like_C_C PF10104.4 AFZ79830.1 - 3.1e-34 117.4 6.0 4.5e-34 116.8 4.1 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain AAA_12 PF13087.1 AFZ79830.1 - 0.046 13.0 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ammonium_transp PF00909.16 AFZ79830.1 - 0.19 10.1 0.4 2.8 6.3 0.1 2.0 2 0 0 2 2 2 0 Ammonium Transporter Family DNA_gyraseA_C PF03989.8 AFZ79831.1 - 0.0012 18.1 0.1 0.0032 16.7 0.0 1.9 2 1 0 2 2 2 1 DNA gyrase C-terminal domain, beta-propeller DNA_topoisoIV PF00521.15 AFZ79833.1 - 2.9e-122 408.5 0.1 4.3e-122 408.0 0.1 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A FAINT PF04385.10 AFZ79835.1 - 7e-35 118.7 3.0 7.1e-09 35.3 0.0 6.7 6 0 0 6 6 6 6 Domain of unknown function, DUF529 Hydrolase PF00702.21 AFZ79835.1 - 1.2e-16 61.7 0.0 2.2e-15 57.6 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 AFZ79835.1 - 4.5e-16 58.5 0.0 1.5e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 AFZ79835.1 - 1e-12 48.5 0.0 4.5e-12 46.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AFZ79835.1 - 2.8e-08 33.6 0.0 7.4e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AFZ79835.1 - 0.0011 18.5 3.3 0.0028 17.2 0.0 3.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AFZ79835.1 - 0.011 15.9 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase EMA PF02488.10 AFZ79836.1 - 3.8e-103 344.3 14.5 4.4e-103 344.1 10.0 1.0 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 AFZ79836.1 - 0.051 13.4 2.0 1.3 8.9 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function, DUF529 Lipase_3 PF01764.20 AFZ79836.1 - 0.1 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PP2 PF14299.1 AFZ79836.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Phloem protein 2 WXG100 PF06013.7 AFZ79837.1 - 0.11 12.5 0.2 1.6 8.7 0.0 3.1 4 0 0 4 4 4 0 Proteins of 100 residues with WXG Hemerythrin PF01814.18 AFZ79837.1 - 0.12 12.5 1.7 19 5.4 0.1 2.9 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain DUF948 PF06103.6 AFZ79837.1 - 1.3 8.9 13.4 1.4 8.8 0.4 4.9 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF842 PF05811.8 AFZ79837.1 - 4.1 6.8 7.9 1.5 8.2 0.7 3.0 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) Zn-ribbon_8 PF09723.5 AFZ79841.1 - 0.03 14.2 0.4 0.088 12.7 0.3 1.7 1 0 0 1 1 1 0 Zinc ribbon domain vMSA PF00695.14 AFZ79843.1 - 8.7 5.4 7.7 14 4.7 3.2 2.0 1 1 1 2 2 2 0 Major surface antigen from hepadnavirus Ribosomal_L12 PF00542.14 AFZ79844.1 - 5.1e-24 84.0 0.9 6e-24 83.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain DUF605 PF04652.11 AFZ79845.1 - 6.4 6.0 16.2 9.9 5.4 11.2 1.2 1 0 0 1 1 1 0 Vta1 like Ribosomal_L12 PF00542.14 AFZ79846.1 - 0.024 14.6 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain AAA_22 PF13401.1 AFZ79847.1 - 0.00036 20.6 0.0 0.00095 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 AFZ79847.1 - 0.0019 17.9 0.5 0.0098 15.6 0.1 2.3 2 1 0 2 2 2 1 Archaeal ATPase NB-ARC PF00931.17 AFZ79847.1 - 0.0052 15.6 0.0 0.12 11.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.1 AFZ79847.1 - 0.072 12.9 0.3 2 8.3 0.2 2.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 AFZ79847.1 - 0.1 12.5 0.0 0.33 10.9 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase zf-DHHC PF01529.15 AFZ79849.1 - 1.5e-30 105.9 12.9 1.5e-30 105.9 8.9 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 AFZ79849.1 - 0.13 12.0 0.5 0.24 11.1 0.4 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF669 PF05037.8 AFZ79851.1 - 0.04 13.8 0.0 0.046 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF669) DUF2990 PF11693.3 AFZ79852.1 - 0.16 11.8 0.2 0.73 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) FAINT PF04385.10 AFZ79853.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79854.1 - 8.8e-26 89.5 6.3 2.4e-05 24.1 0.1 4.4 4 0 0 4 4 4 4 Domain of unknown function, DUF529 Ribosomal_S5 PF00333.15 AFZ79856.1 - 2e-26 91.5 1.2 4.3e-26 90.4 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 AFZ79856.1 - 1.1e-19 69.4 0.1 3e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain CRAL_TRIO PF00650.15 AFZ79858.1 - 2.5e-27 95.3 1.0 4.9e-22 78.1 0.0 3.2 3 0 0 3 3 3 2 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AFZ79858.1 - 4.5e-07 29.9 0.1 1.1e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain FAINT PF04385.10 AFZ79859.1 - 1.7e-25 88.6 9.1 1.4e-06 28.0 0.1 7.0 6 1 1 7 7 7 6 Domain of unknown function, DUF529 Rhodanese PF00581.15 AFZ79859.1 - 0.032 14.5 0.1 0.09 13.1 0.1 1.8 1 0 0 1 1 1 0 Rhodanese-like domain Isy1 PF06246.7 AFZ79863.1 - 7.9e-75 251.5 4.8 8.8e-75 251.4 3.3 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Cyto_heme_lyase PF01265.12 AFZ79864.1 - 8e-37 127.2 0.3 9.6e-37 126.9 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ASF1_hist_chap PF04729.8 AFZ79865.1 - 7e-30 103.6 0.1 1.3e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 ASF1 like histone chaperone BSP_II PF05432.6 AFZ79865.1 - 0.0094 15.2 14.2 0.013 14.7 9.8 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Spt5_N PF11942.3 AFZ79865.1 - 6.3 7.4 16.9 1.9 9.1 6.6 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ASF1_hist_chap PF04729.8 AFZ79867.1 - 5.7e-19 68.2 0.0 5.9e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone Botulinum_HA-17 PF05588.6 AFZ79867.1 - 0.08 12.8 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Clostridium botulinum HA-17 protein PI3_PI4_kinase PF00454.22 AFZ79868.1 - 1.6e-27 96.4 0.2 4.2e-27 95.1 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 AFZ79868.1 - 8.6e-11 41.0 0.3 2.6e-10 39.5 0.2 1.9 1 0 0 1 1 1 1 FATC domain FAINT PF04385.10 AFZ79869.1 - 7.2e-08 32.1 25.2 0.00058 19.6 0.8 6.5 6 2 0 6 6 6 4 Domain of unknown function, DUF529 FimH_man-bind PF09160.5 AFZ79869.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 FimH, mannose binding DUF2510 PF10708.4 AFZ79869.1 - 0.15 11.4 0.1 21 4.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2510) FAINT PF04385.10 AFZ79870.1 - 1.4e-13 50.4 1.1 6e-06 26.0 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FHA PF00498.21 AFZ79870.1 - 5.3e-10 39.2 0.0 1.3e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain DUF2360 PF10152.4 AFZ79870.1 - 0.046 14.0 2.3 5.6 7.2 0.7 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF3530 PF12048.3 AFZ79870.1 - 4.5 6.1 8.8 0.44 9.4 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3530) Collagen PF01391.13 AFZ79871.1 - 8.7e-08 31.5 20.1 2.5e-07 30.1 14.0 1.7 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF1777 PF08648.7 AFZ79872.1 - 7.6e-05 22.5 14.4 8.1e-05 22.4 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) FHA PF00498.21 AFZ79872.1 - 0.0039 17.2 0.1 0.0084 16.2 0.1 1.5 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 AFZ79872.1 - 6.9 5.0 15.0 8.2 4.7 10.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 EMA PF02488.10 AFZ79873.1 - 1.5e-06 27.8 3.5 0.0013 18.2 0.0 3.4 2 2 1 3 3 3 2 Merozoite Antigen FAINT PF04385.10 AFZ79873.1 - 0.0012 18.5 0.1 0.0012 18.5 0.1 3.4 4 0 0 4 4 4 2 Domain of unknown function, DUF529 zf-B_box PF00643.19 AFZ79874.1 - 1.7e-06 27.8 11.6 2.9e-06 27.0 8.0 1.4 1 0 0 1 1 1 1 B-box zinc finger eIF3_N PF09440.5 AFZ79874.1 - 0.039 14.1 1.9 0.06 13.5 1.1 1.4 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain DUF148 PF02520.12 AFZ79874.1 - 0.089 12.5 5.3 0.094 12.5 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF148 Exonuc_VII_L PF02601.10 AFZ79874.1 - 0.13 11.4 0.9 0.15 11.2 0.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Remorin_C PF03763.8 AFZ79874.1 - 0.13 11.7 2.5 0.22 11.0 1.7 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region GIT1_C PF12205.3 AFZ79875.1 - 0.11 12.3 0.0 0.67 9.8 0.0 2.0 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term HPPK PF01288.15 AFZ79876.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF2507 PF10702.4 AFZ79877.1 - 0.15 11.7 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) HsbA PF12296.3 AFZ79878.1 - 0.24 11.2 0.0 0.4 10.5 0.0 1.2 1 0 0 1 1 1 0 Hydrophobic surface binding protein A GlcNAc PF11397.3 AFZ79880.1 - 0.072 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) FAINT PF04385.10 AFZ79881.1 - 2.9e-13 49.4 26.3 4.1e-05 23.3 0.7 6.7 7 0 0 7 7 7 4 Domain of unknown function, DUF529 CENP-B_dimeris PF09026.5 AFZ79881.1 - 1.3 9.3 15.2 7.7 6.8 10.5 2.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAINT PF04385.10 AFZ79883.1 - 1.8e-09 37.3 0.1 8.7e-06 25.5 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function, DUF529 UCR_UQCRX_QCR9 PF05365.7 AFZ79883.1 - 0.0071 15.9 1.3 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Abhydrolase_6 PF12697.2 AFZ79885.1 - 7.4e-13 48.8 0.0 2.8e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ79885.1 - 5.3e-12 45.7 0.0 1.6e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ79885.1 - 1.5e-08 34.3 0.2 3.6e-07 29.9 0.1 2.5 2 0 0 2 2 2 1 Putative lysophospholipase FAINT PF04385.10 AFZ79885.1 - 6.1e-05 22.7 10.8 0.0077 16.0 1.8 4.4 3 0 0 3 3 3 1 Domain of unknown function, DUF529 Peptidase_S9 PF00326.16 AFZ79885.1 - 0.0022 17.2 0.1 1 8.5 0.0 2.9 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 AFZ79885.1 - 0.0044 16.6 0.1 0.088 12.3 0.1 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 AFZ79885.1 - 0.015 14.9 0.0 0.072 12.6 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 AFZ79885.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DUF829 PF05705.9 AFZ79885.1 - 0.017 14.8 0.1 0.15 11.7 0.0 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Abhydrolase_2 PF02230.11 AFZ79885.1 - 0.11 11.9 0.0 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FAINT PF04385.10 AFZ79887.1 - 6.6e-19 67.5 18.3 1.3e-06 28.1 0.9 4.5 4 1 0 4 4 4 4 Domain of unknown function, DUF529 P3A PF08727.6 AFZ79887.1 - 0.071 12.4 0.0 4.9 6.5 0.0 2.7 2 0 0 2 2 2 0 Poliovirus 3A protein like DUF1149 PF06619.6 AFZ79888.1 - 0.033 14.1 0.4 0.066 13.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1149) DUF4199 PF13858.1 AFZ79888.1 - 0.091 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) XylR_N PF06505.6 AFZ79888.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Activator of aromatic catabolism zf-CCCH PF00642.19 AFZ79891.1 - 2.8e-05 23.6 24.5 0.0014 18.2 1.0 4.9 6 0 0 6 6 6 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Chorein_N PF12624.2 AFZ79892.1 - 1.6e-09 37.3 0.2 1e-08 34.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 AFZ79892.1 - 0.029 13.6 5.5 0.019 14.2 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1162) FAINT PF04385.10 AFZ79893.1 - 6.1e-14 51.6 0.5 6.9e-07 29.0 0.9 2.5 2 1 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79893.1 - 7.7e-05 22.2 1.7 0.00019 20.9 1.2 1.7 1 1 0 1 1 1 1 Merozoite Antigen Anillin PF08174.6 AFZ79894.1 - 0.015 15.3 0.1 0.074 13.1 0.0 2.1 2 0 0 2 2 2 0 Cell division protein anillin FAINT PF04385.10 AFZ79895.1 - 7.7e-13 48.1 1.0 4.7e-07 29.5 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79895.1 - 1.5e-06 27.9 5.5 0.0016 17.9 0.0 2.1 1 1 1 2 2 2 2 Merozoite Antigen FAINT PF04385.10 AFZ79896.1 - 5.2e-17 61.4 1.4 3.3e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 S4 PF01479.20 AFZ79900.1 - 0.041 13.3 0.1 0.076 12.4 0.1 1.4 1 0 0 1 1 1 0 S4 domain COX2_TM PF02790.10 AFZ79902.1 - 0.0011 18.8 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain ATP_bind_3 PF01171.15 AFZ79903.1 - 1.5e-17 63.7 0.0 2.7e-17 62.8 0.0 1.4 1 1 0 1 1 1 1 PP-loop family PAPS_reduct PF01507.14 AFZ79903.1 - 0.00096 19.0 0.0 0.0022 17.8 0.0 1.8 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF2392 PF10288.4 AFZ79903.1 - 0.1 12.9 0.0 0.29 11.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2392) Ras PF00071.17 AFZ79904.1 - 1.4e-58 196.8 0.3 1.8e-58 196.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AFZ79904.1 - 2.6e-21 76.3 0.1 3.8e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AFZ79904.1 - 3.3e-18 65.5 0.1 7.4e-18 64.3 0.1 1.5 1 1 1 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AFZ79904.1 - 3.9e-11 42.5 0.1 4.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AFZ79904.1 - 8.7e-08 31.8 0.1 1.4e-06 27.8 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AFZ79904.1 - 3.4e-06 26.4 0.0 4.9e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 AFZ79904.1 - 0.00019 21.3 0.1 0.11 12.3 0.0 2.7 3 0 0 3 3 3 2 Dynamin family MMR_HSR1 PF01926.18 AFZ79904.1 - 0.00021 21.2 0.1 0.0011 18.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AFZ79904.1 - 0.0076 15.5 0.4 0.069 12.4 0.1 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_28 PF13521.1 AFZ79904.1 - 0.02 14.8 0.1 0.22 11.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 AFZ79904.1 - 0.026 14.0 0.1 0.08 12.4 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 AFZ79904.1 - 0.036 13.9 0.1 0.084 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AFZ79904.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF2461 PF09365.5 AFZ79906.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) Tim54 PF11711.3 AFZ79906.1 - 6.6 5.2 11.7 0.059 11.9 2.6 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FAINT PF04385.10 AFZ79907.1 - 0.0004 20.1 1.0 0.00082 19.1 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Ribosomal_L18e PF00828.14 AFZ79908.1 - 1.2e-21 77.4 0.1 1.2e-21 77.4 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 OprF PF05736.6 AFZ79908.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 OprF membrane domain DUF641 PF04859.7 AFZ79909.1 - 6.9e-06 25.8 1.2 0.0096 15.6 0.5 2.4 2 0 0 2 2 2 2 Plant protein of unknown function (DUF641) DUF4111 PF13427.1 AFZ79909.1 - 0.0043 16.8 0.1 0.0097 15.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) P4Ha_N PF08336.6 AFZ79909.1 - 0.013 15.3 1.3 0.03 14.1 0.9 1.5 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TRF PF08558.5 AFZ79909.1 - 0.38 10.0 4.0 0.44 9.8 1.3 1.8 1 1 1 2 2 2 0 Telomere repeat binding factor (TRF) Syntaxin PF00804.20 AFZ79909.1 - 1.3 9.2 6.8 1.4 9.0 1.5 3.1 1 1 0 2 2 2 0 Syntaxin Ribosomal_L18ae PF01775.12 AFZ79910.1 - 1.6e-52 176.5 0.2 2.1e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain TAFA PF12020.3 AFZ79910.1 - 0.078 13.0 0.1 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 TAFA family FAINT PF04385.10 AFZ79911.1 - 0.00013 21.7 0.6 0.00013 21.7 0.4 1.9 2 1 0 2 2 2 1 Domain of unknown function, DUF529 Glyco_hydro_1 PF00232.13 AFZ79913.1 - 0.038 12.1 0.5 0.053 11.6 0.4 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 ATP-synt_C PF00137.16 AFZ79914.1 - 3.3e-13 49.3 10.8 5.3e-13 48.6 7.5 1.3 1 0 0 1 1 1 1 ATP synthase subunit C FAINT PF04385.10 AFZ79916.1 - 2.9e-12 46.2 0.5 0.0049 16.6 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79917.1 - 7.3e-21 73.8 7.8 5.1e-07 29.4 0.0 4.6 4 0 0 4 4 4 4 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79917.1 - 1.2e-09 38.0 3.9 2.7e-07 30.3 0.2 3.8 4 0 0 4 4 4 2 Merozoite Antigen F5_F8_type_C PF00754.20 AFZ79917.1 - 0.03 14.1 0.5 0.37 10.6 0.1 2.8 2 0 0 2 2 2 0 F5/8 type C domain Abhydrolase_6 PF12697.2 AFZ79919.1 - 3.6e-12 46.6 0.0 5.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ79919.1 - 3.9e-10 39.4 0.2 6e-08 32.4 0.1 2.5 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 AFZ79919.1 - 6.6e-07 29.1 0.0 1.8e-06 27.7 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AFZ79919.1 - 0.011 15.3 0.0 0.043 13.3 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 AFZ79919.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.7 AFZ79919.1 - 0.11 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) FAINT PF04385.10 AFZ79920.1 - 2e-10 40.3 3.1 2e-05 24.3 0.1 2.6 2 1 0 2 2 2 2 Domain of unknown function, DUF529 MerC PF03203.9 AFZ79922.1 - 3.4e-13 49.9 8.4 4.4e-13 49.6 5.8 1.1 1 0 0 1 1 1 1 MerC mercury resistance protein DUF2101 PF09874.4 AFZ79922.1 - 0.023 14.1 0.7 0.03 13.8 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) YopE PF03545.8 AFZ79922.1 - 0.037 13.9 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Yersinia virulence determinant (YopE) Chromate_transp PF02417.10 AFZ79922.1 - 0.038 13.6 3.6 0.048 13.2 2.5 1.1 1 0 0 1 1 1 0 Chromate transporter DUF3133 PF11331.3 AFZ79922.1 - 0.078 12.5 0.7 7.1 6.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) DUF4491 PF14898.1 AFZ79922.1 - 3.9 7.6 6.5 0.72 10.0 1.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4491) RRM_1 PF00076.17 AFZ79923.1 - 8e-35 118.3 0.0 1.5e-16 59.8 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ79923.1 - 3.2e-30 103.8 0.0 1.2e-14 54.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ79923.1 - 2.9e-20 71.8 0.0 9.2e-09 35.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AFZ79923.1 - 2.2e-07 30.5 0.0 0.0035 17.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Ribosomal_L2 PF00181.18 AFZ79924.1 - 0.024 14.5 0.3 0.051 13.5 0.2 1.5 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain DUF1341 PF07071.6 AFZ79924.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1341) FAINT PF04385.10 AFZ79925.1 - 2.1e-10 40.3 1.4 0.00068 19.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79926.1 - 0.0014 18.4 0.8 0.0014 18.4 0.5 3.1 3 1 1 4 4 4 1 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79927.1 - 6e-16 58.0 4.8 2.4e-05 24.0 0.1 5.4 4 2 1 5 5 5 4 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79927.1 - 0.0034 16.8 9.6 0.021 14.2 4.9 2.5 2 0 0 2 2 2 1 Merozoite Antigen FAINT PF04385.10 AFZ79928.1 - 2e-42 142.9 13.4 3.8e-06 26.6 0.1 8.9 8 1 0 8 8 8 8 Domain of unknown function, DUF529 A_deaminase PF00962.17 AFZ79929.1 - 1.8e-70 237.5 0.0 2e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF378 PF04070.7 AFZ79929.1 - 0.0056 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF378) FAINT PF04385.10 AFZ79931.1 - 0.018 14.8 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79932.1 - 0.027 13.9 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Merozoite Antigen ParG PF09274.5 AFZ79932.1 - 0.044 13.7 0.1 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 ParG Methyltransf_18 PF12847.2 AFZ79934.1 - 0.0043 17.6 0.0 0.013 16.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AFZ79934.1 - 0.05 13.6 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_10 PF05971.7 AFZ79934.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF890) TTL PF03133.10 AFZ79935.1 - 1.7e-48 165.0 0.4 2.4e-48 164.5 0.2 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 AFZ79935.1 - 8.2e-10 37.9 0.1 1.9e-06 26.8 0.0 3.1 2 1 1 3 3 3 2 YheC/D like ATP-grasp RimK PF08443.6 AFZ79935.1 - 0.0017 17.8 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.1 AFZ79935.1 - 0.046 13.4 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain GSH-S_ATP PF02955.11 AFZ79935.1 - 0.17 10.9 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain Prenyltrans PF00432.16 AFZ79936.1 - 1.3e-42 142.9 0.8 3.6e-11 42.4 0.0 5.6 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AFZ79936.1 - 1.2e-23 83.6 0.0 1.2e-15 57.8 0.0 4.2 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 AFZ79936.1 - 0.012 15.5 0.0 3.6 7.6 0.0 3.0 1 1 2 3 3 3 0 Prenyltransferase-like DUF4041 PF13250.1 AFZ79936.1 - 0.034 13.6 0.0 0.08 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) SSXT PF05030.7 AFZ79937.1 - 0.00019 20.9 1.6 0.0012 18.4 0.1 2.6 2 1 0 2 2 2 1 SSXT protein (N-terminal region) EF-hand_1 PF00036.27 AFZ79938.1 - 2.8e-06 26.2 0.7 0.034 13.4 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 AFZ79938.1 - 2.8e-05 24.1 3.9 0.0017 18.4 1.7 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 AFZ79938.1 - 3.2e-05 23.4 0.4 0.13 11.9 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 AFZ79938.1 - 0.0021 17.2 1.2 1.1 8.7 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 AFZ79938.1 - 0.0054 16.5 0.2 3.2 7.8 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain PITH PF06201.8 AFZ79940.1 - 2.9e-31 108.3 0.0 3.4e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 PITH domain Saw1 PF11561.3 AFZ79942.1 - 0.03 13.7 1.4 0.15 11.4 0.9 1.8 1 1 0 1 1 1 0 Single strand annealing-weakened 1 Reprolysin_3 PF13582.1 AFZ79945.1 - 0.016 15.7 0.2 0.21 12.1 0.2 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like RRM_1 PF00076.17 AFZ79946.1 - 3.6e-39 132.2 0.0 1.7e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ79946.1 - 3e-25 87.9 0.0 1e-12 47.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ79946.1 - 1.7e-14 53.4 0.0 3.1e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AFZ79946.1 - 0.0019 17.9 0.2 0.099 12.4 0.0 2.4 2 1 0 2 2 2 1 Limkain b1 Auto_anti-p27 PF06677.7 AFZ79947.1 - 1e-11 44.3 2.7 1.7e-11 43.6 1.9 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Thioredoxin PF00085.15 AFZ79948.1 - 2.7e-10 39.8 0.0 4.2e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 AFZ79948.1 - 1.9e-09 36.6 0.1 2.2e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 Phosducin tRNA_m1G_MT PF01746.16 AFZ79949.1 - 1.8e-25 89.6 0.0 2.3e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Peptidase_M24 PF00557.19 AFZ79950.1 - 1.3e-43 148.9 0.0 1.7e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 AFZ79950.1 - 0.0026 17.5 6.4 0.012 15.4 4.5 2.2 1 1 0 1 1 1 1 MYND finger DUF1851 PF08906.6 AFZ79950.1 - 0.051 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1851) NTP_transf_2 PF01909.18 AFZ79952.1 - 2.3e-06 27.8 0.0 6.3e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 AFZ79952.1 - 0.065 13.1 1.8 0.15 11.9 0.8 2.1 3 0 0 3 3 3 0 Cid1 family poly A polymerase Cpn60_TCP1 PF00118.19 AFZ79953.1 - 5.2e-126 421.1 10.2 6.1e-126 420.8 7.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UPF0051 PF01458.12 AFZ79954.1 - 0.013 14.9 0.7 0.018 14.4 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein family (UPF0051) Ribosomal_S5 PF00333.15 AFZ79955.1 - 3.4e-07 29.8 0.1 6.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 AFZ79955.1 - 0.00023 20.3 0.0 0.00046 19.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain TryThrA_C PF12319.3 AFZ79955.1 - 0.65 9.1 5.3 0.1 11.7 0.6 1.8 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal FAINT PF04385.10 AFZ79956.1 - 2.2e-08 33.8 2.0 5.7e-08 32.4 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function, DUF529 DUF2914 PF11141.3 AFZ79959.1 - 0.12 11.9 0.2 0.46 10.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) Histone PF00125.19 AFZ79962.1 - 8.9e-19 67.3 0.3 1.3e-18 66.8 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 AFZ79962.1 - 0.0027 17.9 0.7 0.0036 17.5 0.0 1.5 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 AFZ79962.1 - 0.0082 16.1 0.5 0.018 15.0 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PHD PF00628.24 AFZ79963.1 - 3.5e-12 45.8 6.7 3.5e-12 45.8 4.7 2.5 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 AFZ79963.1 - 6.2e-10 38.7 20.2 1.1e-09 37.9 4.3 2.5 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 AFZ79963.1 - 1.3e-08 34.8 11.8 6.9e-08 32.4 2.4 2.5 2 0 0 2 2 2 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 AFZ79963.1 - 1.3e-07 31.1 19.8 5e-07 29.2 5.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AFZ79963.1 - 2.4e-06 27.1 4.4 2.4e-06 27.1 3.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AFZ79963.1 - 2.8e-06 26.9 5.6 2.8e-06 26.9 3.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AFZ79963.1 - 7.1e-05 22.7 19.5 0.00013 21.9 5.8 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AFZ79963.1 - 0.047 13.4 3.6 0.13 12.0 2.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 AFZ79963.1 - 0.049 13.4 10.0 0.28 11.0 1.2 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 AFZ79963.1 - 0.37 10.6 10.0 1.1 9.1 0.6 2.8 2 1 0 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.1 AFZ79963.1 - 3.7 7.5 15.1 0.2 11.5 4.5 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Tmemb_cc2 PF10267.4 AFZ79964.1 - 0.15 10.5 1.5 0.22 10.1 1.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein FAINT PF04385.10 AFZ79965.1 - 8.2e-10 38.3 0.7 3e-06 26.9 0.6 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79965.1 - 1.2e-05 24.9 0.5 0.0089 15.5 0.0 2.7 3 0 0 3 3 3 2 Merozoite Antigen zf-RING_2 PF13639.1 AFZ79966.1 - 0.45 10.3 12.5 6.2 6.7 7.0 3.5 2 1 0 2 2 2 0 Ring finger domain Mut7-C PF01927.11 AFZ79966.1 - 0.56 10.1 5.8 0.25 11.3 1.4 2.3 2 0 0 2 2 2 0 Mut7-C RNAse domain IFT46_B_C PF12317.3 AFZ79967.1 - 0.013 14.9 1.2 0.015 14.6 0.8 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Peptidase_S64 PF08192.6 AFZ79967.1 - 0.015 13.6 2.3 0.017 13.5 1.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF1664 PF07889.7 AFZ79967.1 - 0.094 12.5 2.7 1.3 8.8 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4211 PF13926.1 AFZ79967.1 - 0.13 11.6 4.4 0.12 11.7 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4211) WEMBL PF05701.6 AFZ79967.1 - 0.14 10.6 1.5 0.26 9.6 1.1 1.3 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF730 PF05325.6 AFZ79967.1 - 0.19 11.5 3.4 1.1 9.1 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF730) DUF342 PF03961.8 AFZ79967.1 - 0.2 10.0 3.1 0.66 8.3 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Nsp1_C PF05064.8 AFZ79967.1 - 0.21 11.2 4.1 17 5.0 0.2 3.2 2 1 0 3 3 3 0 Nsp1-like C-terminal region DUF1160 PF06648.6 AFZ79967.1 - 0.21 11.3 3.9 1.2 8.9 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1160) Prp18 PF02840.10 AFZ79967.1 - 0.3 10.8 1.7 0.97 9.2 0.1 2.0 1 1 1 2 2 2 0 Prp18 domain LXG PF04740.7 AFZ79967.1 - 0.37 10.5 9.7 0.19 11.5 3.6 2.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily Ribosomal_L18_c PF14204.1 AFZ79967.1 - 1.5 9.4 4.9 11 6.6 0.9 2.4 1 1 1 2 2 2 0 Ribosomal L18 C-terminal region FlaC_arch PF05377.6 AFZ79967.1 - 1.5 8.7 5.3 0.88 9.5 0.2 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-C4H2 PF10146.4 AFZ79967.1 - 1.5 8.7 6.2 2.5 8.0 4.2 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein FAINT PF04385.10 AFZ79968.1 - 1.1e-17 63.6 0.0 5.9e-08 32.4 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79972.1 - 1.2e-71 241.1 0.7 1.4e-71 240.9 0.5 1.0 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 AFZ79973.1 - 0.004 16.9 1.5 0.004 16.9 1.1 3.0 2 1 0 2 2 2 1 Domain of unknown function, DUF529 Sugar_tr PF00083.19 AFZ79974.1 - 4.8e-60 203.4 33.7 5.9e-60 203.1 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AFZ79974.1 - 5e-12 45.2 34.2 3.6e-08 32.5 8.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AFZ79974.1 - 6.5e-05 21.3 3.4 6.5e-05 21.3 2.4 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FAINT PF04385.10 AFZ79976.1 - 2.3e-06 27.3 0.0 0.0051 16.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 BPL_LplA_LipB PF03099.14 AFZ79976.1 - 0.12 12.3 0.1 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 Biotin/lipoate A/B protein ligase family FAINT PF04385.10 AFZ79977.1 - 5.3e-10 38.9 0.0 0.042 13.7 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79978.1 - 2e-16 59.5 2.3 4.2e-06 26.5 0.0 3.7 3 1 0 3 3 3 3 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ79981.1 - 5.1e-08 32.6 0.4 8.9e-08 31.8 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 EMA PF02488.10 AFZ79981.1 - 0.045 13.2 0.2 0.059 12.8 0.1 1.1 1 0 0 1 1 1 0 Merozoite Antigen UQ_con PF00179.21 AFZ79983.1 - 7.3e-44 148.5 0.0 8.4e-44 148.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AFZ79983.1 - 0.0023 17.6 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 AFZ79983.1 - 0.0093 15.6 0.2 0.023 14.3 0.1 1.8 2 1 0 2 2 2 1 UEV domain RWD PF05773.17 AFZ79983.1 - 0.06 13.2 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain MCM PF00493.18 AFZ79984.1 - 6.1e-106 353.9 0.0 1.2e-105 353.0 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AFZ79984.1 - 4.9e-09 36.7 0.0 3e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 AFZ79984.1 - 1.2e-08 34.7 0.0 2.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AFZ79984.1 - 2.1e-08 33.5 0.2 0.0018 17.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AFZ79984.1 - 0.0005 19.6 0.0 0.0018 17.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 AFZ79984.1 - 0.00074 19.7 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AFZ79984.1 - 0.0051 16.2 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 AFZ79984.1 - 0.016 15.3 0.6 0.15 12.1 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.1 AFZ79984.1 - 0.029 14.3 0.7 0.15 12.0 0.0 2.5 2 1 1 3 3 3 0 AAA ATPase domain NACHT PF05729.7 AFZ79984.1 - 0.034 13.8 0.2 0.89 9.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 AFZ79984.1 - 0.062 13.6 0.1 0.36 11.1 0.0 2.1 2 1 0 2 2 2 0 ABC transporter Miro PF08477.8 AFZ79984.1 - 0.079 13.4 0.0 0.24 11.8 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein EMP24_GP25L PF01105.19 AFZ79985.1 - 2.9e-30 105.3 2.3 3.3e-30 105.1 1.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ribosom_S12_S23 PF00164.20 AFZ79987.1 - 2.5e-37 126.9 0.9 4.2e-37 126.2 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 FAINT PF04385.10 AFZ79988.1 - 1.5e-25 88.7 5.7 0.00027 20.7 0.0 6.6 6 0 0 6 6 6 6 Domain of unknown function, DUF529 ICE2 PF08426.5 AFZ79989.1 - 0.045 12.3 0.1 0.062 11.9 0.1 1.1 1 0 0 1 1 1 0 ICE2 DUF3047 PF11249.3 AFZ79989.1 - 0.11 11.9 0.3 3.5 6.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3047) HSP70 PF00012.15 AFZ79994.1 - 4.4e-15 54.6 0.3 4.4e-15 54.6 0.2 1.8 1 1 1 2 2 2 1 Hsp70 protein TPR_11 PF13414.1 AFZ79994.1 - 1.8e-13 49.8 1.9 2.8e-06 26.8 0.1 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 AFZ79994.1 - 3.6e-05 23.1 5.2 0.0043 16.6 0.1 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AFZ79994.1 - 0.00032 20.4 1.3 0.11 12.4 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 AFZ79994.1 - 0.0012 18.8 0.1 0.012 15.7 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 AFZ79994.1 - 0.0055 16.5 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 AFZ79994.1 - 0.013 15.4 0.4 0.26 11.2 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 AFZ79994.1 - 0.018 14.8 1.7 0.036 13.9 0.1 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain MAS20 PF02064.10 AFZ79994.1 - 0.02 14.7 2.9 0.021 14.7 0.7 2.0 2 0 0 2 2 2 0 MAS20 protein import receptor TPR_6 PF13174.1 AFZ79994.1 - 0.022 15.1 0.2 5 7.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AFZ79994.1 - 0.052 14.1 0.0 1.2 9.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ79994.1 - 0.065 13.0 0.6 6.5 6.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 AFZ79994.1 - 0.29 11.8 0.5 5.2 7.8 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat HSP70 PF00012.15 AFZ79995.1 - 4.7e-09 34.7 0.0 4.8e-09 34.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein GATase_2 PF00310.16 AFZ79996.1 - 0.065 11.9 0.0 0.082 11.6 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Lambda_Kil PF06301.6 AFZ79996.1 - 0.067 12.6 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage lambda Kil protein Flavokinase PF01687.12 AFZ79998.1 - 6.2e-27 93.9 0.0 7.8e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase LAGLIDADG_3 PF14528.1 AFZ79998.1 - 0.046 13.9 0.1 0.5 10.6 0.1 2.3 2 0 0 2 2 2 0 LAGLIDADG-like domain YqhR PF11085.3 AFZ79998.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Conserved membrane protein YqhR CcdA PF07362.7 AFZ79999.1 - 0.0028 17.5 0.2 0.0093 15.8 0.1 1.9 1 0 0 1 1 1 1 Post-segregation antitoxin CcdA Toxin_10 PF05431.6 AFZ79999.1 - 0.017 14.7 0.7 0.057 13.0 0.5 1.9 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 DASH_Dad2 PF08654.5 AFZ79999.1 - 0.22 11.5 5.2 0.47 10.4 0.8 3.3 3 1 0 3 3 3 0 DASH complex subunit Dad2 BLOC1_2 PF10046.4 AFZ79999.1 - 0.27 11.3 15.1 0.35 11.0 0.8 3.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_min_cap2 PF06152.6 AFZ79999.1 - 0.41 9.5 13.6 0.051 12.5 3.7 2.6 2 2 1 3 3 3 0 Phage minor capsid protein 2 Herpes_U30 PF04523.8 AFZ79999.1 - 1.7 5.9 6.3 0.98 6.7 0.4 2.1 2 0 0 2 2 2 0 Herpes virus tegument protein U30 DUF883 PF05957.8 AFZ79999.1 - 7.8 6.9 8.2 29 5.1 0.2 4.0 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF2577 PF10844.3 AFZ80001.1 - 0.097 12.7 0.3 3.1 7.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2577) Aldo_ket_red PF00248.16 AFZ80005.1 - 4.3e-60 202.9 0.0 4.9e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAM176 PF14851.1 AFZ80007.1 - 0.28 10.8 3.6 0.19 11.3 1.6 1.4 1 1 0 1 1 1 0 FAM176 family DUF2254 PF10011.4 AFZ80010.1 - 0.29 9.5 2.7 0.69 8.3 1.9 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Ribosomal_S13_N PF08069.7 AFZ80011.1 - 7.3e-28 96.1 0.3 1.4e-27 95.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 AFZ80011.1 - 3.6e-22 77.9 0.9 7.5e-22 76.8 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein S15 Viral_P18 PF04521.8 AFZ80013.1 - 0.024 14.0 0.5 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein FAINT PF04385.10 AFZ80014.1 - 0.00033 20.4 0.5 0.098 12.5 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80015.1 - 2.2e-37 126.7 19.1 2.2e-12 46.6 1.5 6.4 6 0 0 6 6 6 5 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80015.1 - 1e-10 41.5 14.0 6.7e-05 22.4 2.2 4.0 4 1 0 4 4 4 3 Merozoite Antigen DUF3519 PF12033.3 AFZ80015.1 - 0.044 13.9 0.3 0.044 13.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) FAINT PF04385.10 AFZ80016.1 - 3e-30 103.8 16.9 3.4e-11 42.8 0.4 6.1 6 0 0 6 6 6 5 Domain of unknown function, DUF529 NOT2_3_5 PF04153.13 AFZ80016.1 - 0.029 14.2 2.8 8.6 6.2 0.1 4.0 4 0 0 4 4 4 0 NOT2 / NOT3 / NOT5 family FAINT PF04385.10 AFZ80017.1 - 1.2e-08 34.6 2.0 0.0004 20.1 0.1 2.5 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80018.1 - 1.4e-05 24.8 0.0 0.004 16.9 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80018.1 - 3.5e-05 23.4 0.1 0.0057 16.1 0.0 2.0 1 1 0 2 2 2 2 Merozoite Antigen CBFD_NFYB_HMF PF00808.18 AFZ80021.1 - 0.18 11.8 0.3 0.4 10.7 0.2 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Med9 PF07544.8 AFZ80022.1 - 0.0031 17.2 5.2 0.36 10.6 0.0 3.5 3 0 0 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 DUF4111 PF13427.1 AFZ80022.1 - 0.016 14.9 0.1 0.045 13.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) DUF641 PF04859.7 AFZ80022.1 - 0.069 12.9 0.4 0.069 12.9 0.3 2.7 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Abp2 PF09441.5 AFZ80022.1 - 0.085 12.7 0.1 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 ARS binding protein 2 MitMem_reg PF13012.1 AFZ80022.1 - 0.27 11.3 4.6 0.25 11.4 0.7 2.5 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function Prefoldin_2 PF01920.15 AFZ80022.1 - 0.32 10.7 9.9 1.8 8.3 3.5 3.3 2 1 1 3 3 3 0 Prefoldin subunit Laminin_II PF06009.7 AFZ80022.1 - 0.33 10.7 7.7 2.1 8.0 0.0 3.4 3 1 0 3 3 3 0 Laminin Domain II DUF948 PF06103.6 AFZ80022.1 - 0.55 10.1 5.6 13 5.6 0.6 4.4 3 3 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Zw10 PF06248.8 AFZ80022.1 - 0.57 8.2 8.1 0.073 11.2 2.7 1.6 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 DUF4298 PF14131.1 AFZ80022.1 - 1.5 8.7 7.9 8.6 6.3 0.1 4.2 4 1 0 5 5 5 0 Domain of unknown function (DUF4298) DUF1978 PF09321.5 AFZ80022.1 - 5.6 6.3 11.4 0.78 9.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1978) FAINT PF04385.10 AFZ80024.1 - 0.0013 18.5 0.1 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Myosin_head PF00063.16 AFZ80026.1 - 1.4e-172 575.3 0.1 2.4e-172 574.5 0.1 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 AFZ80026.1 - 0.039 14.0 0.1 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 AFZ80026.1 - 0.15 10.9 0.0 0.3 9.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein FAINT PF04385.10 AFZ80028.1 - 4.9e-11 42.3 9.8 4e-09 36.1 0.3 3.2 2 1 1 3 3 3 2 Domain of unknown function, DUF529 Phage_tail_X PF05489.7 AFZ80028.1 - 0.084 12.3 0.1 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Phage Tail Protein X DUF751 PF05421.6 AFZ80029.1 - 0.083 13.1 6.7 0.079 13.2 2.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF751) Aspzincin_M35 PF14521.1 AFZ80029.1 - 0.093 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase FAINT PF04385.10 AFZ80031.1 - 2.5e-15 56.0 4.8 0.00021 21.0 0.0 4.1 3 1 1 4 4 4 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 AFZ80031.1 - 5.7e-11 42.7 0.0 1.1e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ80031.1 - 4.4e-07 29.6 0.1 3.5e-05 23.5 0.0 2.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 AFZ80031.1 - 1.4e-05 24.8 0.0 3.7e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AFZ80031.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Elf1 PF05129.8 AFZ80032.1 - 0.0023 17.5 1.2 0.61 9.8 0.1 3.1 2 0 0 2 2 2 2 Transcription elongation factor Elf1 like FAINT PF04385.10 AFZ80034.1 - 0.0023 17.7 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function, DUF529 MIP-T3 PF10243.4 AFZ80035.1 - 7.5 4.8 26.2 13 4.1 18.2 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FAINT PF04385.10 AFZ80036.1 - 1.6e-25 88.7 1.2 1e-06 28.4 0.0 4.5 4 0 0 4 4 4 4 Domain of unknown function, DUF529 Exo_endo_phos PF03372.18 AFZ80038.1 - 3.1e-19 69.9 0.0 5.7e-19 69.0 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.17 AFZ80039.1 - 4.5e-54 179.9 0.3 4.8e-19 67.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ80039.1 - 3.7e-40 135.7 1.1 9.2e-13 47.9 0.0 3.5 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ80039.1 - 1.6e-29 101.4 2.2 8.6e-09 35.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 AFZ80039.1 - 5.7e-10 38.8 4.9 1.1e-09 37.9 3.4 1.5 1 0 0 1 1 1 1 WW domain RNA_bind PF08675.6 AFZ80039.1 - 6.9e-07 29.1 0.0 0.038 13.9 0.0 3.4 3 0 0 3 3 3 2 RNA binding domain Nup35_RRM PF05172.8 AFZ80039.1 - 0.00058 19.5 0.0 0.037 13.7 0.0 2.8 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 AFZ80039.1 - 0.00081 19.1 0.0 0.052 13.3 0.0 3.1 3 0 0 3 3 3 1 Limkain b1 DUF1866 PF08952.6 AFZ80039.1 - 0.022 14.3 0.0 0.19 11.2 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) RNB PF00773.14 AFZ80040.1 - 2.6e-92 309.5 0.0 4e-92 308.9 0.0 1.3 1 0 0 1 1 1 1 RNB domain MoaC PF01967.16 AFZ80040.1 - 0.026 14.2 0.6 0.8 9.3 0.2 2.4 2 0 0 2 2 2 0 MoaC family Na_trans_assoc PF06512.8 AFZ80041.1 - 0.16 11.9 18.7 0.16 11.9 1.2 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated DUF1510 PF07423.6 AFZ80041.1 - 0.83 8.9 23.5 0.073 12.4 7.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 AFZ80041.1 - 1.1 6.8 2.7 1.8 6.1 1.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM176 PF14851.1 AFZ80041.1 - 2.8 7.6 15.6 8.7 6.0 6.5 2.5 2 0 0 2 2 2 0 FAM176 family Prothymosin PF03247.9 AFZ80041.1 - 9.8 6.3 43.2 6.7 6.9 18.3 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family DUF3551 PF12071.3 AFZ80042.1 - 0.063 12.8 0.7 0.1 12.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3551) PEPCK_ATP PF01293.15 AFZ80043.1 - 5.7e-46 157.0 0.0 6.8e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEPCK_ATP PF01293.15 AFZ80045.1 - 3.7e-153 510.4 0.0 4.2e-153 510.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 AFZ80045.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AFZ80045.1 - 0.037 14.8 0.0 0.087 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 AFZ80045.1 - 0.045 13.3 0.1 0.13 11.8 0.0 1.8 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_29 PF13555.1 AFZ80045.1 - 0.072 12.6 0.2 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 AFZ80045.1 - 0.076 12.9 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 AFZ80045.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain GILT PF03227.11 AFZ80045.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) AP2 PF00847.15 AFZ80046.1 - 2.5e-17 62.7 2.2 6.9e-07 29.3 0.1 3.5 3 0 0 3 3 3 3 AP2 domain UDPGP PF01704.13 AFZ80048.1 - 3.8e-17 61.9 0.0 9.8e-11 40.7 0.0 2.4 3 0 0 3 3 3 2 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 AFZ80048.1 - 6.1e-07 29.6 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Kelch_1 PF01344.20 AFZ80049.1 - 3.9e-57 189.5 2.7 4.4e-11 42.1 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 AFZ80049.1 - 6.2e-33 111.6 1.9 1.3e-05 25.1 0.0 6.3 4 1 2 6 6 6 6 Kelch motif Kelch_4 PF13418.1 AFZ80049.1 - 6.2e-25 86.7 7.8 0.00011 21.9 0.0 6.3 4 2 2 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 AFZ80049.1 - 2.1e-22 78.6 2.9 2.2e-05 24.4 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB_2 PF02214.17 AFZ80049.1 - 5e-18 65.0 0.1 2e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.1 AFZ80049.1 - 1.3e-10 41.0 4.4 0.14 12.1 0.0 6.5 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.10 AFZ80049.1 - 1.6e-10 40.3 5.9 0.014 15.1 0.0 6.2 5 1 1 6 6 6 3 Kelch motif OST3_OST6 PF04756.8 AFZ80051.1 - 0.0028 17.2 3.5 0.023 14.2 2.5 2.1 1 1 0 1 1 1 1 OST3 / OST6 family Chorein_N PF12624.2 AFZ80052.1 - 2.4e-21 75.4 0.7 7.5e-21 73.8 0.5 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter WD40 PF00400.27 AFZ80053.1 - 8.5e-36 120.5 3.7 3.5e-06 26.6 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 AFZ80053.1 - 2.9e-12 45.6 0.4 6.2e-12 44.5 0.2 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like FAINT PF04385.10 AFZ80054.1 - 0.00082 19.1 0.2 0.02 14.7 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function, DUF529 GIDA_assoc_3 PF13932.1 AFZ80055.1 - 0.0028 17.6 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 GidA associated domain 3 MFS_1 PF07690.11 AFZ80056.1 - 1.3e-14 53.7 66.5 1.1e-11 44.0 3.5 4.2 1 1 3 4 4 4 4 Major Facilitator Superfamily GCV_T PF01571.16 AFZ80057.1 - 9e-30 103.6 0.0 1.7e-28 99.4 0.0 2.3 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 AFZ80057.1 - 3.3e-12 46.2 0.0 7.3e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain HSP70 PF00012.15 AFZ80058.1 - 5.7e-66 222.6 14.0 2.1e-59 201.0 6.8 3.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 AFZ80058.1 - 4.1e-05 22.3 0.4 0.00012 20.7 0.3 1.8 1 1 0 1 1 1 1 MreB/Mbl protein FHA PF00498.21 AFZ80059.1 - 7.3e-14 51.6 0.0 2.9e-12 46.4 0.0 2.6 2 0 0 2 2 2 1 FHA domain RINGv PF12906.2 AFZ80059.1 - 3e-12 46.3 7.6 3e-12 46.3 5.2 2.0 2 0 0 2 2 2 1 RING-variant domain FANCL_C PF11793.3 AFZ80059.1 - 0.0049 16.7 3.1 0.0049 16.7 2.2 2.3 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.1 AFZ80059.1 - 0.0055 16.5 6.8 0.015 15.1 4.7 1.8 1 0 0 1 1 1 1 Ring finger domain OTCace_N PF02729.16 AFZ80060.1 - 4e-46 156.2 0.0 6.3e-46 155.5 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 AFZ80060.1 - 3.9e-41 140.5 0.0 6e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PITH PF06201.8 AFZ80061.1 - 1.8e-40 138.1 0.2 2.1e-40 137.9 0.1 1.0 1 0 0 1 1 1 1 PITH domain PhnA PF03831.9 AFZ80061.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 PhnA protein HVSL PF09749.4 AFZ80063.1 - 1.1e-30 106.4 0.1 2.4e-30 105.3 0.1 1.6 1 1 0 1 1 1 1 Uncharacterised conserved protein FAINT PF04385.10 AFZ80064.1 - 2e-08 33.9 1.0 3e-08 33.3 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80065.1 - 8.6e-17 60.7 5.2 6.3e-05 22.7 1.3 4.0 3 1 0 3 3 3 3 Domain of unknown function, DUF529 CDK5_activator PF03261.10 AFZ80065.1 - 0.061 12.6 6.5 0.11 11.8 4.5 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein zf-RING_2 PF13639.1 AFZ80067.1 - 0.0037 17.0 5.9 0.012 15.4 3.8 2.0 1 1 1 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 AFZ80067.1 - 0.0053 16.5 1.7 0.0071 16.1 1.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger HMG_box_2 PF09011.5 AFZ80067.1 - 0.012 15.9 1.9 0.017 15.4 1.3 1.1 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.14 AFZ80067.1 - 0.026 14.8 1.6 0.035 14.3 1.1 1.1 1 0 0 1 1 1 0 HMG (high mobility group) box DUF3113 PF11310.3 AFZ80067.1 - 0.041 13.5 0.1 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) zf-C3HC4 PF00097.20 AFZ80067.1 - 0.18 11.4 7.9 0.66 9.6 5.4 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HSA PF07529.8 AFZ80067.1 - 0.24 11.2 4.9 0.32 10.8 3.4 1.2 1 0 0 1 1 1 0 HSA zf-RING_5 PF14634.1 AFZ80067.1 - 0.25 11.1 6.8 8.3 6.2 4.9 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.2 AFZ80067.1 - 0.45 10.6 5.7 0.69 10.0 3.4 1.7 1 1 1 2 2 2 0 RING-H2 zinc finger Bac_small_YrzI PF09501.5 AFZ80067.1 - 2 8.3 4.8 4.9 7.1 3.3 1.6 1 1 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) zf-C3HC4_2 PF13923.1 AFZ80067.1 - 2.9 7.9 10.6 3 7.9 3.6 2.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AFZ80067.1 - 4.8 7.1 7.7 4.2 7.3 3.2 2.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING Thioredoxin PF00085.15 AFZ80068.1 - 1.5e-23 82.4 0.0 3.6e-23 81.2 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 AFZ80068.1 - 5.4e-08 33.0 0.3 2.3e-07 30.9 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AFZ80068.1 - 1.7e-07 31.2 0.2 4.3e-05 23.5 0.1 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 AFZ80068.1 - 1.5e-06 28.1 0.0 2.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 AFZ80068.1 - 1.8e-05 24.3 0.0 3.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.1 AFZ80068.1 - 0.00089 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.1 AFZ80068.1 - 0.039 13.4 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein KaiB PF07689.7 AFZ80068.1 - 0.041 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 KaiB domain DUF836 PF05768.9 AFZ80068.1 - 0.068 13.4 0.1 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DIM1 PF02966.11 AFZ80068.1 - 0.07 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 Redoxin PF08534.5 AFZ80068.1 - 0.091 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Redoxin FAINT PF04385.10 AFZ80069.1 - 1.8e-13 50.1 3.6 9.6e-06 25.3 0.0 4.4 4 0 0 4 4 4 3 Domain of unknown function, DUF529 Rhomboid PF01694.17 AFZ80070.1 - 3.3e-09 36.9 5.6 4.7e-09 36.4 3.9 1.1 1 0 0 1 1 1 1 Rhomboid family DUF2340 PF10209.4 AFZ80071.1 - 0.14 12.3 1.2 3.1 7.9 0.8 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2340) DUF3561 PF12084.3 AFZ80074.1 - 0.0016 18.2 0.4 0.0017 18.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3561) FAINT PF04385.10 AFZ80075.1 - 7.9e-11 41.6 0.0 3.8e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF605 PF04652.11 AFZ80077.1 - 4.9 6.4 9.5 8 5.7 6.6 1.3 1 0 0 1 1 1 0 Vta1 like IMCp PF12314.3 AFZ80079.1 - 9.1e-18 64.2 59.8 9e-14 51.3 16.7 2.5 1 1 1 2 2 2 2 Inner membrane complex protein Maf1 PF09174.5 AFZ80079.1 - 0.018 14.9 0.1 0.062 13.1 0.1 1.9 1 0 0 1 1 1 0 Maf1 regulator Dopey_N PF04118.9 AFZ80081.1 - 1.4e-101 339.3 3.9 1.7e-101 339.0 1.1 2.5 2 0 0 2 2 2 1 Dopey, N-terminal FAINT PF04385.10 AFZ80082.1 - 0.036 13.8 0.3 0.063 13.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function, DUF529 DUF1923 PF09083.5 AFZ80083.1 - 0.013 14.9 0.2 6.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) Class_IIIsignal PF04021.7 AFZ80083.1 - 7.9 6.3 6.9 15 5.4 4.8 1.5 1 0 0 1 1 1 0 Class III signal peptide DUF2628 PF10947.3 AFZ80085.1 - 8.6 6.2 8.9 5.3 6.8 1.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Bromodomain PF00439.20 AFZ80086.1 - 1.4e-23 82.5 1.2 4.2e-23 81.0 0.5 2.0 2 0 0 2 2 2 1 Bromodomain Acetyltransf_7 PF13508.1 AFZ80086.1 - 2.1e-11 43.8 1.8 4.1e-11 42.8 1.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AFZ80086.1 - 2.9e-10 40.0 0.2 5.2e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AFZ80086.1 - 4e-05 23.7 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AFZ80086.1 - 0.0029 17.3 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 AFZ80086.1 - 0.0035 17.4 0.4 0.032 14.3 0.0 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AFZ80086.1 - 0.0051 16.6 0.3 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AUX_IAA PF02309.11 AFZ80086.1 - 0.02 14.6 0.6 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 AUX/IAA family Phage_Mu_Gam PF07352.7 AFZ80086.1 - 0.065 12.7 1.4 0.15 11.6 0.0 2.2 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Put_DNA-bind_N PF06971.8 AFZ80090.1 - 0.15 11.8 0.4 0.91 9.3 0.1 2.4 1 1 1 2 2 2 0 Putative DNA-binding protein N-terminus FAINT PF04385.10 AFZ80091.1 - 5.1e-16 58.2 0.8 1.1e-07 31.6 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80091.1 - 2.5e-08 33.7 0.6 1.4e-07 31.2 0.4 1.9 1 1 0 1 1 1 1 Merozoite Antigen CHB_HEX_C_1 PF13290.1 AFZ80092.1 - 0.0038 16.9 0.5 0.011 15.4 0.3 1.8 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 AFZ80092.1 - 0.023 14.7 0.1 0.08 13.0 0.1 2.0 1 0 0 1 1 1 0 Fn3 associated Herpes_UL17 PF04559.7 AFZ80092.1 - 0.32 9.5 0.6 0.43 9.0 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein FAINT PF04385.10 AFZ80093.1 - 2.7e-09 36.7 0.0 0.0015 18.3 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80093.1 - 0.023 14.1 0.1 0.044 13.2 0.0 1.6 1 1 0 1 1 1 0 Merozoite Antigen FAINT PF04385.10 AFZ80095.1 - 5.5e-16 58.1 13.4 2.7e-07 30.3 0.2 4.9 5 0 0 5 5 5 4 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80095.1 - 2.3e-08 33.8 1.1 2.3e-08 33.8 0.8 3.1 1 1 2 3 3 3 1 Merozoite Antigen Lyase_8_C PF02884.12 AFZ80095.1 - 0.042 13.8 0.1 0.39 10.7 0.0 2.5 3 0 0 3 3 3 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Zn_ribbon_2 PF12674.2 AFZ80095.1 - 0.069 13.5 2.3 12 6.3 0.0 3.1 3 0 0 3 3 3 0 Putative zinc ribbon domain RVT_1 PF00078.22 AFZ80098.1 - 1.4e-34 119.3 0.1 2.4e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAINT PF04385.10 AFZ80099.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, DUF529 ABC_tran PF00005.22 AFZ80100.1 - 9.7e-32 110.1 0.0 3.1e-17 63.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 AFZ80100.1 - 2.6e-05 24.3 0.1 0.065 13.2 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 AFZ80100.1 - 2.9e-05 24.1 9.6 0.021 14.7 0.1 4.8 5 0 0 5 5 4 2 AAA domain AAA_29 PF13555.1 AFZ80100.1 - 8.2e-05 22.0 0.7 0.2 11.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.1 AFZ80100.1 - 8.3e-05 22.2 0.1 0.022 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AFZ80100.1 - 8.4e-05 22.8 0.1 0.41 10.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 AFZ80100.1 - 0.00015 21.2 0.0 0.042 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 AFZ80100.1 - 0.00015 22.1 6.4 0.04 14.2 0.3 3.1 3 0 0 3 3 3 2 AAA domain ArgK PF03308.11 AFZ80100.1 - 0.00032 19.5 0.2 0.001 17.9 0.0 1.7 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 AFZ80100.1 - 0.00038 21.2 0.2 0.43 11.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 AFZ80100.1 - 0.0012 18.0 0.2 1.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF258 PF03193.11 AFZ80100.1 - 0.0019 17.4 0.3 0.2 10.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 AFZ80100.1 - 0.0019 17.7 0.2 0.77 9.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 AFZ80100.1 - 0.0024 17.7 1.4 0.11 12.3 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 T2SE PF00437.15 AFZ80100.1 - 0.0031 16.4 0.5 1.6 7.5 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein UPF0079 PF02367.12 AFZ80100.1 - 0.0081 15.7 0.8 0.15 11.7 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 AFZ80100.1 - 0.0089 15.2 1.0 0.17 11.0 0.0 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain MobB PF03205.9 AFZ80100.1 - 0.011 15.4 0.4 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 AFZ80100.1 - 0.019 14.6 0.4 2.2 7.8 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 AFZ80100.1 - 0.024 14.7 0.1 12 6.0 0.1 2.7 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 AFZ80100.1 - 0.029 12.9 0.5 4.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 AFZ80100.1 - 0.031 14.0 1.1 3.9 7.2 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain Dynamin_N PF00350.18 AFZ80100.1 - 0.039 13.7 0.3 3.7 7.3 0.0 2.6 2 0 0 2 2 2 0 Dynamin family SbcCD_C PF13558.1 AFZ80100.1 - 0.042 13.7 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 AFZ80100.1 - 0.043 14.3 0.1 18 5.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NB-ARC PF00931.17 AFZ80100.1 - 0.066 12.0 0.1 0.86 8.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 AFZ80100.1 - 0.08 12.3 1.7 10 5.4 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 AFZ80100.1 - 0.081 12.8 0.0 0.76 9.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 AFZ80100.1 - 0.093 12.4 0.2 5.4 6.6 0.1 2.5 2 0 0 2 2 2 0 NTPase DUF2791 PF10923.3 AFZ80100.1 - 0.11 11.0 0.0 1.3 7.5 0.0 2.3 3 0 0 3 3 3 0 P-loop Domain of unknown function (DUF2791) AAA_33 PF13671.1 AFZ80100.1 - 0.19 11.5 0.1 7 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 AFZ80100.1 - 0.2 11.0 0.5 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CIAPIN1 PF05093.8 AFZ80102.1 - 8.5e-24 83.5 13.4 4.1e-22 78.1 9.3 2.3 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF3184 PF11380.3 AFZ80102.1 - 0.089 10.7 0.0 0.13 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) tRNA-synt_2b PF00587.20 AFZ80103.1 - 6.1e-59 198.4 0.0 7.4e-58 194.9 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AFZ80103.1 - 2.5e-23 81.8 0.0 9.5e-23 79.9 0.0 2.1 1 0 0 1 1 1 1 Anticodon binding domain zf-DNL PF05180.7 AFZ80104.1 - 4e-29 100.1 1.2 4e-29 100.1 0.9 1.9 2 0 0 2 2 2 1 DNL zinc finger Lar_restr_allev PF14354.1 AFZ80104.1 - 0.0071 16.6 1.5 0.09 13.0 0.4 2.7 1 1 1 2 2 2 1 Restriction alleviation protein Lar CGGC PF08821.6 AFZ80104.1 - 0.013 15.5 0.1 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 CGGC domain Myticin-prepro PF10690.4 AFZ80104.1 - 0.24 11.4 1.8 0.18 11.8 0.2 1.7 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel Elf1 PF05129.8 AFZ80104.1 - 0.28 10.8 2.5 0.2 11.3 0.2 1.9 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like MutS_III PF05192.13 AFZ80106.1 - 2.1e-28 99.5 0.2 6e-28 98.0 0.1 1.8 1 0 0 1 1 1 1 MutS domain III MutS_V PF00488.16 AFZ80106.1 - 4.3e-18 65.5 0.0 8.2e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_IV PF05190.13 AFZ80106.1 - 6.8e-06 26.1 0.6 1.8e-05 24.7 0.2 2.0 2 0 0 2 2 2 1 MutS family domain IV MliC PF09864.4 AFZ80106.1 - 0.018 14.7 1.6 8.1 6.2 0.0 3.2 3 0 0 3 3 3 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme FAINT PF04385.10 AFZ80107.1 - 5.7e-15 54.9 3.9 2.2e-06 27.4 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function, DUF529 MutS_V PF00488.16 AFZ80108.1 - 2.5e-61 207.0 0.1 2.9e-61 206.8 0.1 1.0 1 0 0 1 1 1 1 MutS domain V DUF1902 PF08972.6 AFZ80113.1 - 0.16 11.5 0.1 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) RRM_1 PF00076.17 AFZ80118.1 - 1.1e-05 25.0 0.0 2.7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ80118.1 - 0.0024 17.8 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ80118.1 - 0.013 15.3 0.0 0.05 13.4 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IPPT PF01715.12 AFZ80119.1 - 1.2e-34 119.5 1.2 1.5e-34 119.2 0.9 1.1 1 0 0 1 1 1 1 IPP transferase NOT2_3_5 PF04153.13 AFZ80119.1 - 0.041 13.7 0.3 0.087 12.7 0.2 1.6 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family Smoothelin PF12510.3 AFZ80119.1 - 0.082 12.7 0.2 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein IPT PF01745.11 AFZ80119.1 - 0.097 11.8 0.1 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Isopentenyl transferase GCN5L1 PF06320.8 AFZ80119.1 - 0.78 9.5 5.1 1.6 8.5 2.0 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) AAA_18 PF13238.1 AFZ80119.1 - 1.3 9.3 6.3 0.49 10.6 1.4 2.1 1 1 1 2 2 2 0 AAA domain FAINT PF04385.10 AFZ80120.1 - 2.7e-11 43.1 0.0 2.4e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 IPPT PF01715.12 AFZ80121.1 - 3.2e-23 82.0 0.0 5.2e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 IPP transferase IPT PF01745.11 AFZ80121.1 - 0.0001 21.5 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Isopentenyl transferase AAA_17 PF13207.1 AFZ80121.1 - 0.00024 21.8 0.1 0.0024 18.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AFZ80121.1 - 0.002 18.0 0.0 0.048 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AFZ80121.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 AFZ80121.1 - 0.12 12.1 0.1 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase Nop14 PF04147.7 AFZ80121.1 - 6.6 4.5 11.9 9.1 4.0 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 AFZ80121.1 - 9.6 4.1 9.4 16 3.4 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein FAA_hydrolase_N PF09298.6 AFZ80122.1 - 0.026 14.5 0.9 0.3 11.0 0.1 2.4 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal DEK_C PF08766.6 AFZ80122.1 - 0.099 12.4 2.2 0.33 10.7 0.2 2.5 2 0 0 2 2 2 0 DEK C terminal domain DUF2203 PF09969.4 AFZ80122.1 - 1 9.6 8.1 0.74 10.0 0.4 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) AARP2CN PF08142.7 AFZ80125.1 - 0.017 14.6 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 AARP2CN (NUC121) domain DUF3309 PF11752.3 AFZ80125.1 - 0.082 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) DUF3989 PF13150.1 AFZ80125.1 - 0.24 10.8 1.8 13 5.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Vps51 PF08700.6 AFZ80127.1 - 0.011 15.5 1.5 0.062 13.1 1.0 2.3 1 0 0 1 1 1 0 Vps51/Vps67 Mur_ligase_M PF08245.7 AFZ80128.1 - 2.5e-05 24.4 0.0 3.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_M PF08245.7 AFZ80131.1 - 0.0034 17.4 0.0 0.0043 17.1 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain TetR_C_5 PF08360.6 AFZ80131.1 - 0.033 14.1 0.1 0.043 13.7 0.1 1.1 1 0 0 1 1 1 0 QacR-like protein, C-terminal region Tau95 PF09734.4 AFZ80133.1 - 1.2e-38 133.2 0.0 2.4e-38 132.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit GCC2_GCC3 PF07699.8 AFZ80134.1 - 1.2e-25 88.8 125.7 7.5e-08 31.8 3.0 12.7 11 1 1 12 12 12 9 GCC2 and GCC3 FlgI PF02119.11 AFZ80134.1 - 1 7.9 0.9 1.7 7.1 0.6 1.2 1 0 0 1 1 1 0 Flagellar P-ring protein Tmemb_cc2 PF10267.4 AFZ80135.1 - 0.0055 15.3 0.0 0.0087 14.6 0.0 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein GCC2_GCC3 PF07699.8 AFZ80138.1 - 4.5e-37 125.3 96.9 2.6e-10 39.6 2.4 11.6 12 0 0 12 12 12 9 GCC2 and GCC3 SirB PF04247.7 AFZ80138.1 - 0.19 11.4 2.9 0.89 9.2 2.0 2.0 1 1 0 1 1 1 0 Invasion gene expression up-regulator, SirB Med21 PF11221.3 AFZ80138.1 - 1.3 9.0 1.9 2.1 8.3 1.3 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex HCV_capsid PF01543.12 AFZ80139.1 - 0.094 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Hepatitis C virus capsid protein LRR_9 PF14580.1 AFZ80140.1 - 1.5e-16 60.4 0.0 1.5e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 AFZ80140.1 - 0.0014 18.1 1.3 0.2 11.3 0.6 2.1 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AFZ80140.1 - 0.089 12.8 0.8 8.5 6.8 0.2 2.4 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_9 PF14580.1 AFZ80143.1 - 2.9e-24 85.5 0.1 3.7e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 AFZ80143.1 - 9.6e-09 34.6 3.3 7.7e-06 25.4 1.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AFZ80143.1 - 2.4e-07 30.4 8.4 1.6e-05 24.5 1.3 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 AFZ80143.1 - 0.04 13.9 1.8 46 4.6 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat BACON PF13004.2 AFZ80147.1 - 0.035 14.3 0.1 0.2 11.9 0.1 2.3 1 0 0 1 1 1 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal MIF4G PF02854.14 AFZ80148.1 - 6.6e-07 28.9 0.7 1.9e-06 27.4 0.5 1.8 1 0 0 1 1 1 1 MIF4G domain MIF4G_like_2 PF09090.6 AFZ80148.1 - 1.1e-06 28.0 0.3 2.8e-06 26.7 0.2 1.6 1 0 0 1 1 1 1 MIF4G like Parvo_coat PF00740.13 AFZ80150.1 - 0.011 14.7 6.8 0.014 14.3 4.7 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF2383 PF09537.5 AFZ80150.1 - 4.8 7.4 13.9 0.086 13.0 1.9 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF2383) Mitofilin PF09731.4 AFZ80150.1 - 7.3 5.1 38.2 14 4.1 26.4 1.4 1 1 0 1 1 1 0 Mitochondrial inner membrane protein FTP PF07504.8 AFZ80152.1 - 0.022 14.2 0.0 0.048 13.1 0.0 1.6 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif Apc4 PF12896.2 AFZ80153.1 - 0.081 12.2 0.2 0.099 11.9 0.2 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Cys_rich_CPXG PF14255.1 AFZ80154.1 - 0.042 13.6 3.0 0.049 13.4 0.3 2.4 3 0 0 3 3 3 0 Cysteine-rich CPXCG SFTA2 PF15210.1 AFZ80155.1 - 0.23 11.0 0.1 0.23 11.0 0.1 2.4 3 0 0 3 3 3 0 Surfactant-associated protein 2 UFC1 PF08694.6 AFZ80156.1 - 2.3e-80 267.6 0.1 2.6e-80 267.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.21 AFZ80156.1 - 0.0039 16.6 0.2 0.012 15.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AFZ80156.1 - 0.0076 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Pox_P4B PF03292.9 AFZ80156.1 - 0.12 10.2 0.0 0.15 9.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein Hydrolase_3 PF08282.7 AFZ80157.1 - 2.7e-26 92.6 0.0 2.3e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 AFZ80157.1 - 0.00014 22.1 0.0 0.00099 19.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TBP PF00352.16 AFZ80159.1 - 5.4e-21 73.7 2.0 1.5e-05 24.2 0.0 4.4 4 0 0 4 4 4 4 Transcription factor TFIID (or TATA-binding protein, TBP) RF-1 PF00472.15 AFZ80160.1 - 1.1e-05 25.2 3.6 1.4e-05 24.8 2.5 1.1 1 0 0 1 1 1 1 RF-1 domain VPS28 PF03997.7 AFZ80160.1 - 0.044 13.4 0.2 0.059 12.9 0.1 1.1 1 0 0 1 1 1 0 VPS28 protein RF-1 PF00472.15 AFZ80162.1 - 4.6e-18 65.0 0.0 7.5e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 AFZ80162.1 - 8.1e-10 38.4 0.0 1.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 PCRF domain Pkinase PF00069.20 AFZ80163.1 - 8.5e-11 41.4 0.2 4.6e-10 39.0 0.1 2.3 1 1 1 2 2 2 1 Protein kinase domain RWD PF05773.17 AFZ80163.1 - 3.4e-07 30.1 0.2 1e-06 28.6 0.2 1.9 1 0 0 1 1 1 1 RWD domain Pkinase_Tyr PF07714.12 AFZ80163.1 - 0.00016 20.8 0.2 0.00048 19.2 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase UQ_con PF00179.21 AFZ80163.1 - 0.028 13.8 0.4 0.18 11.2 0.0 2.5 3 0 0 3 3 3 0 Ubiquitin-conjugating enzyme SPC12 PF06645.8 AFZ80165.1 - 2.7e-11 43.1 4.5 3.4e-11 42.7 3.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2422 PF10337.4 AFZ80165.1 - 0.32 9.7 3.7 0.39 9.4 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) zf-HIT PF04438.11 AFZ80167.1 - 0.038 13.6 0.5 0.075 12.6 0.4 1.4 1 0 0 1 1 1 0 HIT zinc finger YscJ_FliF PF01514.12 AFZ80168.1 - 0.14 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family ABC_tran PF00005.22 AFZ80169.1 - 9.3e-29 100.4 0.0 1.1e-15 58.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 AFZ80169.1 - 3.7e-05 23.7 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.1 AFZ80169.1 - 7.5e-05 22.3 0.2 0.042 13.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AFZ80169.1 - 0.00031 20.2 1.5 0.13 11.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AFZ80169.1 - 0.00034 21.0 5.0 0.18 12.1 0.6 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AFZ80169.1 - 0.0022 17.2 0.4 0.59 9.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 AFZ80169.1 - 0.0022 18.7 0.0 0.52 11.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 AFZ80169.1 - 0.0025 16.6 0.7 0.01 14.6 0.0 2.0 2 0 0 2 2 2 1 ArgK protein AAA_25 PF13481.1 AFZ80169.1 - 0.0032 16.9 0.0 0.18 11.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 AFZ80169.1 - 0.0048 16.1 0.2 1.2 8.2 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family T2SE PF00437.15 AFZ80169.1 - 0.013 14.3 0.7 1.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 AFZ80169.1 - 0.017 14.2 0.3 3 6.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 AFZ80169.1 - 0.02 14.3 0.4 5 6.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 AFZ80169.1 - 0.023 14.3 0.8 0.35 10.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 AFZ80169.1 - 0.034 14.3 0.0 9.3 6.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AFZ80169.1 - 0.038 14.3 0.2 0.97 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 AFZ80169.1 - 0.047 14.1 0.6 12 6.3 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein DUF87 PF01935.12 AFZ80169.1 - 0.055 13.2 3.3 0.095 12.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 AFZ80169.1 - 0.091 12.1 1.3 0.3 10.4 0.0 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein MobB PF03205.9 AFZ80169.1 - 0.097 12.3 0.8 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 AFZ80169.1 - 0.11 11.1 0.3 6.2 5.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SMC_N PF02463.14 AFZ80169.1 - 0.13 11.4 0.9 1.9 7.6 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 AFZ80169.1 - 0.14 11.9 1.1 6.4 6.6 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain FAINT PF04385.10 AFZ80170.1 - 2.7e-75 248.2 89.4 7.4e-07 28.9 3.3 21.3 20 0 0 20 20 20 20 Domain of unknown function, DUF529 TruB-C_2 PF09157.6 AFZ80170.1 - 0.68 9.8 0.0 1.4 8.7 0.0 1.5 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal TPR_11 PF13414.1 AFZ80172.1 - 1e-16 60.2 0.1 3.7e-09 36.1 0.0 3.8 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 AFZ80172.1 - 6.1e-15 53.8 0.0 0.0026 17.5 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 AFZ80172.1 - 4.4e-14 51.3 0.0 0.0012 18.3 0.0 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 AFZ80172.1 - 8.1e-10 38.4 0.0 0.076 13.6 0.0 5.0 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 AFZ80172.1 - 4.8e-09 36.0 0.0 0.0004 20.2 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ80172.1 - 4.1e-08 32.4 0.0 0.29 10.9 0.0 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 AFZ80172.1 - 4.4e-08 33.3 0.0 0.002 18.4 0.0 3.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 AFZ80172.1 - 5.8e-08 33.1 0.0 0.015 15.9 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 AFZ80172.1 - 1.1e-05 25.1 0.0 6.6e-05 22.6 0.0 2.4 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 AFZ80172.1 - 0.00017 21.6 2.1 0.023 14.8 0.0 4.2 4 1 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 AFZ80172.1 - 0.0015 18.5 2.3 0.4 11.0 0.0 5.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 AFZ80172.1 - 0.0024 17.5 0.0 0.11 12.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 AFZ80172.1 - 0.026 14.9 0.0 0.96 10.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_S15 PF00312.17 AFZ80173.1 - 1.3e-15 56.8 0.2 2e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 zf-CHC2 PF01807.15 AFZ80175.1 - 0.065 12.7 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 CHC2 zinc finger Ribosomal_L6 PF00347.18 AFZ80176.1 - 2.9e-24 85.3 3.8 2.9e-13 50.1 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 HR1 PF02185.11 AFZ80177.1 - 0.077 12.7 1.4 15 5.4 0.0 3.5 3 0 0 3 3 3 0 Hr1 repeat FAINT PF04385.10 AFZ80180.1 - 9.3e-08 31.8 4.4 0.00016 21.4 0.5 2.5 2 1 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80180.1 - 0.00018 21.1 1.7 0.021 14.2 0.3 2.1 1 1 0 2 2 2 2 Merozoite Antigen FAINT PF04385.10 AFZ80182.1 - 6.5e-35 118.8 16.5 3e-07 30.1 0.1 6.4 6 0 0 6 6 6 6 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80182.1 - 9.1e-05 22.0 12.9 1.9 7.9 0.1 5.0 4 1 1 5 5 5 4 Merozoite Antigen AviRa PF11599.3 AFZ80182.1 - 0.046 12.7 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa HEAT PF02985.17 AFZ80185.1 - 0.0027 17.6 0.2 37 4.7 0.0 4.0 3 0 0 3 3 3 3 HEAT repeat HEAT_2 PF13646.1 AFZ80185.1 - 0.043 14.0 0.0 0.21 11.8 0.0 2.3 1 0 0 1 1 1 0 HEAT repeats Asn_synthase PF00733.16 AFZ80186.1 - 1.4e-31 109.9 0.0 3.2e-31 108.7 0.0 1.6 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 AFZ80186.1 - 0.059 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain Arginase PF00491.16 AFZ80186.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Arginase family Calici_MSP PF05752.6 AFZ80187.1 - 0.15 11.6 0.3 0.29 10.7 0.2 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein DUF3053 PF11254.3 AFZ80187.1 - 0.42 9.8 3.7 3.5 6.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) MFS_1 PF07690.11 AFZ80189.1 - 3.9e-18 65.2 12.2 5.9e-18 64.6 8.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SurA_N_2 PF13623.1 AFZ80190.1 - 0.0047 16.9 0.1 0.0051 16.7 0.1 1.1 1 0 0 1 1 1 1 SurA N-terminal domain 5_3_exonuc PF01367.15 AFZ80190.1 - 0.13 12.5 0.1 0.21 11.8 0.0 1.4 1 1 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DASH_Dad3 PF08656.5 AFZ80190.1 - 1.3 8.7 5.0 1.6 8.5 1.4 2.0 1 1 1 2 2 2 0 DASH complex subunit Dad3 Wbp11 PF09429.5 AFZ80192.1 - 8.5e-07 28.8 13.0 1.2e-06 28.4 9.0 1.2 1 0 0 1 1 1 1 WW domain binding protein 11 GvpG PF05120.7 AFZ80192.1 - 0.087 12.6 1.2 0.15 11.8 0.8 1.3 1 0 0 1 1 1 0 Gas vesicle protein G YPEB PF14620.1 AFZ80192.1 - 0.12 11.3 2.0 0.17 10.8 1.4 1.1 1 0 0 1 1 1 0 YpeB sporulation TraF PF13728.1 AFZ80192.1 - 0.59 9.5 4.0 0.98 8.8 2.7 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein LRR_4 PF12799.2 AFZ80194.1 - 9.7e-16 57.0 20.0 4.6e-08 32.5 2.2 4.4 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AFZ80194.1 - 1.1e-08 34.6 3.8 6.6e-05 22.5 1.2 2.8 2 1 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.1 AFZ80194.1 - 1.6e-07 31.0 0.2 4.1e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 AFZ80194.1 - 4.3e-06 26.0 0.3 0.64 10.4 0.2 4.6 5 0 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 AFZ80194.1 - 0.00013 21.5 4.7 4.2 7.7 0.2 4.5 4 1 1 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 AFZ80194.1 - 0.00015 21.5 2.2 12 6.3 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich repeat PPP4R2 PF09184.6 AFZ80194.1 - 0.11 12.0 14.4 0.16 11.4 10.0 1.2 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.7 AFZ80194.1 - 0.96 8.6 22.0 1.2 8.2 15.2 1.1 1 0 0 1 1 1 0 SDA1 RNase_PH PF01138.16 AFZ80195.1 - 4.5e-14 52.9 0.1 8.3e-14 52.0 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 DUF3458 PF11940.3 AFZ80197.1 - 5.8e-112 374.1 0.0 7.8e-112 373.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 AFZ80197.1 - 2.3e-61 208.0 0.0 3.1e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 AFZ80197.1 - 4.1e-15 55.9 0.0 8.3e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Exo_endo_phos PF03372.18 AFZ80198.1 - 6.5e-10 39.3 0.0 1.1e-07 32.1 0.0 2.2 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Snf7 PF03357.16 AFZ80199.1 - 1.8e-06 27.4 5.8 2.1e-06 27.2 4.0 1.1 1 0 0 1 1 1 1 Snf7 FbpA PF05833.6 AFZ80199.1 - 0.0098 14.4 7.2 0.013 14.0 4.7 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Dala_Dala_lig_C PF07478.8 AFZ80199.1 - 0.036 13.4 1.0 0.06 12.7 0.7 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF4515 PF14988.1 AFZ80199.1 - 0.16 11.5 10.5 0.11 12.1 6.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) RNB PF00773.14 AFZ80200.1 - 6.9e-80 268.7 0.2 1.1e-79 268.0 0.1 1.4 1 0 0 1 1 1 1 RNB domain Ribosomal_L34 PF00468.12 AFZ80200.1 - 0.078 12.6 0.1 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L34 Coatomer_WDAD PF04053.9 AFZ80201.1 - 2.8e-105 352.6 0.1 1.4e-104 350.4 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 AFZ80201.1 - 3.7e-39 131.2 16.1 1.9e-11 43.3 0.7 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Ribosomal_L35p PF01632.14 AFZ80202.1 - 7.8e-12 44.9 12.4 1.1e-11 44.3 8.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L35 Med26 PF08711.6 AFZ80204.1 - 1.1e-09 37.6 0.0 2.3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DED PF01335.16 AFZ80204.1 - 0.029 14.4 0.2 0.082 13.0 0.2 1.7 1 0 0 1 1 1 0 Death effector domain DKNYY PF13644.1 AFZ80204.1 - 0.071 13.3 0.9 0.086 13.1 0.0 1.5 2 0 0 2 2 2 0 DKNYY family DUF2964 PF11177.3 AFZ80204.1 - 0.087 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) SHMT PF00464.14 AFZ80205.1 - 5.9e-171 568.2 0.0 6.9e-171 568.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 AFZ80205.1 - 0.01 14.8 0.0 0.027 13.4 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II DUF3719 PF12516.3 AFZ80205.1 - 0.09 12.3 0.1 1.3 8.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3719) DUF1929 PF09118.6 AFZ80205.1 - 0.11 12.5 0.0 7.1 6.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1929) ATP-synt_ab PF00006.20 AFZ80206.1 - 6.2e-65 218.6 0.0 9.3e-65 218.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AFZ80206.1 - 1.3e-21 77.1 0.1 2.2e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AFZ80206.1 - 1.8e-19 69.6 0.1 3.8e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 AFZ80206.1 - 0.0018 17.7 0.0 0.017 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 AFZ80206.1 - 0.0036 17.0 0.6 6.7 6.4 0.1 3.7 3 1 1 4 4 4 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 AFZ80206.1 - 0.013 15.7 0.2 0.78 9.9 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AFZ80206.1 - 0.013 15.2 0.1 0.043 13.5 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase KaiC PF06745.8 AFZ80206.1 - 0.022 13.8 0.7 0.041 12.9 0.5 1.4 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 AFZ80206.1 - 0.034 13.3 0.1 0.056 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 AFZ80206.1 - 0.055 13.1 0.1 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 AFZ80206.1 - 0.14 10.9 0.3 0.24 10.2 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 AFZ80206.1 - 0.21 11.1 0.5 12 5.4 0.2 2.3 2 0 0 2 2 2 0 AAA domain MA3 PF02847.12 AFZ80207.1 - 9.7e-13 47.8 0.0 4.2e-12 45.7 0.0 2.2 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.14 AFZ80207.1 - 2.3e-07 30.4 3.4 6.2e-07 29.0 2.4 1.8 1 0 0 1 1 1 1 MIF4G domain DNA_pol_A PF00476.15 AFZ80208.1 - 5.6e-66 222.7 0.5 8.6e-66 222.1 0.4 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 AFZ80208.1 - 4.1e-30 104.5 0.1 1.1e-29 103.1 0.0 1.8 2 0 0 2 2 2 1 3'-5' exonuclease AAA_25 PF13481.1 AFZ80208.1 - 3.8e-21 75.3 0.0 6.8e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.1 AFZ80208.1 - 1e-06 28.9 0.0 3.7e-06 27.1 0.0 2.1 1 0 0 1 1 1 1 Toprim-like AAA_22 PF13401.1 AFZ80208.1 - 1.1e-05 25.5 0.0 3.2e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 AFZ80208.1 - 2.5e-05 23.5 0.0 7.7e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 KaiC Toprim_4 PF13662.1 AFZ80208.1 - 3.2e-05 23.8 0.0 8.2e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.1 AFZ80208.1 - 0.00012 22.2 0.0 0.00037 20.6 0.0 1.9 1 0 0 1 1 1 1 Toprim domain RNase_H_2 PF13482.1 AFZ80208.1 - 0.011 15.5 0.0 0.04 13.7 0.0 2.1 1 0 0 1 1 1 0 RNase_H superfamily AAA_16 PF13191.1 AFZ80208.1 - 0.018 15.0 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 AFZ80208.1 - 0.047 13.9 0.6 0.73 10.1 0.0 2.8 2 0 0 2 2 2 0 ABC transporter LRRNT PF01462.13 AFZ80208.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain zf-ribbon_3 PF13248.1 AFZ80208.1 - 5 6.4 6.3 16 4.8 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Rhomboid PF01694.17 AFZ80210.1 - 7.2e-10 39.0 14.9 7.2e-10 39.0 10.4 1.6 2 0 0 2 2 2 1 Rhomboid family Peptidase_S39 PF02122.10 AFZ80211.1 - 0.073 12.3 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase S39 FAINT PF04385.10 AFZ80212.1 - 0.02 14.6 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, DUF529 dUTPase PF00692.14 AFZ80213.1 - 1.6e-19 69.6 0.0 5.4e-19 67.9 0.0 1.7 1 1 0 1 1 1 1 dUTPase Methyltransf_4 PF02390.12 AFZ80214.1 - 1.1e-42 145.3 0.0 1.3e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 AFZ80214.1 - 0.00064 20.2 0.0 0.0013 19.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AFZ80214.1 - 0.0035 16.9 0.0 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AFZ80214.1 - 0.0085 15.8 0.0 0.048 13.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AFZ80214.1 - 0.021 14.8 0.0 0.053 13.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 AFZ80214.1 - 0.023 14.0 0.0 0.096 12.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.7 AFZ80214.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain LSM PF01423.17 AFZ80215.1 - 6.3e-16 57.6 0.0 7.4e-16 57.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AFZ80215.1 - 7.2e-07 29.0 0.0 1.2e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Ataxin 2 SM domain DEAD PF00270.24 AFZ80217.1 - 8.8e-21 74.1 0.0 3.8e-19 68.7 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ80217.1 - 5.5e-20 71.0 0.1 1.4e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sec23_trunk PF04811.10 AFZ80218.1 - 1.8e-25 89.7 0.2 3.1e-25 88.9 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 AFZ80218.1 - 8.7e-17 61.4 0.1 4e-15 56.1 0.0 2.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 AFZ80218.1 - 7.1e-10 38.2 0.0 3e-09 36.2 0.0 2.1 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 AFZ80218.1 - 1.4e-05 24.5 3.0 1.4e-05 24.5 2.1 2.9 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 AFZ80218.1 - 0.0002 20.9 0.1 0.00053 19.6 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L13 PF00572.13 AFZ80221.1 - 8.7e-31 106.6 0.2 1.2e-30 106.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ubiquitin_2 PF14560.1 AFZ80222.1 - 2.3e-19 69.4 0.1 6.4e-19 68.0 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.20 AFZ80222.1 - 4.3e-14 51.9 0.7 6.7e-14 51.3 0.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.18 AFZ80222.1 - 0.097 12.0 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin family PIH1 PF08190.7 AFZ80222.1 - 0.1 12.0 0.9 0.48 9.8 0.0 1.9 2 0 0 2 2 2 0 pre-RNA processing PIH1/Nop17 Methyltrn_RNA_3 PF02598.12 AFZ80223.1 - 1.7e-59 201.5 0.0 1.4e-58 198.5 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methyltransferase BHD_1 PF10403.4 AFZ80224.1 - 7.2e-07 28.6 0.0 2.1e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.10 AFZ80224.1 - 7.1e-05 22.2 0.1 0.0023 17.3 0.0 2.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 AFZ80224.1 - 0.00024 20.7 0.0 0.00093 18.8 0.0 2.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Phage_glycop_gL PF11108.3 AFZ80224.1 - 0.016 15.1 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 Viral glycoprotein L zf-SNAP50_C PF12251.3 AFZ80225.1 - 0.00084 18.7 0.1 0.00089 18.6 0.0 1.0 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal CDP-OH_P_transf PF01066.16 AFZ80226.1 - 0.094 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase Peptidase_M24 PF00557.19 AFZ80227.1 - 8.8e-29 100.5 0.0 1.2e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 IMPDH PF00478.20 AFZ80228.1 - 1.3e-72 244.6 0.1 3.6e-72 243.1 0.1 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 AFZ80228.1 - 2.2e-06 26.7 0.1 7.2e-06 25.0 0.1 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 AFZ80228.1 - 0.0033 16.7 0.4 0.014 14.7 0.0 2.1 3 0 0 3 3 3 1 Histidine biosynthesis protein NMO PF03060.10 AFZ80228.1 - 0.01 15.0 0.4 0.02 14.0 0.3 1.6 1 1 0 1 1 1 0 Nitronate monooxygenase Glu_synthase PF01645.12 AFZ80228.1 - 0.079 11.8 0.3 0.16 10.8 0.1 1.5 2 0 0 2 2 2 0 Conserved region in glutamate synthase RAP PF08373.5 AFZ80230.1 - 6.9e-07 28.9 0.6 6.9e-07 28.9 0.4 2.2 2 0 0 2 2 2 1 RAP domain RabGAP-TBC PF00566.13 AFZ80231.1 - 7.5e-55 185.6 3.2 1.4e-54 184.7 2.2 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 AFZ80232.1 - 5.9e-63 212.4 0.1 3.1e-40 137.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ80232.1 - 2.5e-29 102.1 0.0 8.7e-24 83.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 AFZ80232.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 AFZ80233.1 - 1.2e-09 37.7 11.2 9.7e-05 22.0 0.3 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Med21 PF11221.3 AFZ80234.1 - 0.00013 21.9 0.9 0.00016 21.6 0.7 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex TBPIP PF07106.8 AFZ80234.1 - 0.0033 16.9 3.0 0.0044 16.5 2.1 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1192 PF06698.6 AFZ80234.1 - 0.084 12.7 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Reo_sigmaC PF04582.7 AFZ80234.1 - 0.18 10.9 0.6 0.24 10.5 0.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Actin PF00022.14 AFZ80235.1 - 7.5e-60 202.3 0.0 1.6e-59 201.3 0.0 1.4 1 1 0 1 1 1 1 Actin MFS_1 PF07690.11 AFZ80237.1 - 2.3e-17 62.7 11.1 4.4e-17 61.8 7.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 AFZ80237.1 - 3.4e-05 22.4 16.4 0.00021 19.8 2.2 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein Ribosomal_L5_C PF00673.16 AFZ80238.1 - 1.2e-25 89.0 0.0 1.7e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AFZ80238.1 - 9.4e-18 63.7 0.2 2.3e-17 62.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_S13 PF00416.17 AFZ80239.1 - 1e-35 122.4 1.7 1.2e-35 122.1 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 AFZ80239.1 - 0.0025 16.4 0.0 0.0029 16.2 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) RAP PF08373.5 AFZ80241.1 - 0.0014 18.3 0.2 0.0039 16.9 0.2 1.8 1 0 0 1 1 1 1 RAP domain ING PF12998.2 AFZ80243.1 - 3.1e-07 30.6 1.5 2.3e-05 24.6 1.1 2.3 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding DUF4284 PF14112.1 AFZ80243.1 - 0.042 14.3 0.2 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4284) SBDS_C PF09377.5 AFZ80244.1 - 1e-28 99.5 0.1 2e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 AFZ80244.1 - 7.7e-28 96.1 0.9 1.8e-27 94.9 0.6 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF916 PF06030.7 AFZ80244.1 - 0.049 13.4 0.4 9.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) zf-C2H2 PF00096.21 AFZ80244.1 - 0.22 11.9 3.2 0.78 10.2 2.2 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type Maelstrom PF13017.1 AFZ80245.1 - 0.49 9.8 2.7 0.52 9.7 0.2 2.0 2 0 0 2 2 2 0 piRNA pathway germ-plasm component GTP_EFTU PF00009.22 AFZ80246.1 - 6.2e-49 165.9 0.0 9.1e-49 165.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 AFZ80246.1 - 5.3e-16 58.2 0.0 9.5e-16 57.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 AFZ80246.1 - 6.4e-09 35.5 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 AFZ80246.1 - 2.7e-06 27.3 0.0 6.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AFZ80246.1 - 0.00025 21.5 0.0 0.00058 20.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 AFZ80246.1 - 0.0092 15.1 0.0 0.26 10.3 0.0 2.3 2 0 0 2 2 2 1 AIG1 family zf-RING_4 PF14570.1 AFZ80247.1 - 2.8e-19 68.4 12.3 6.3e-19 67.2 8.6 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 AFZ80247.1 - 1.8e-07 30.6 6.7 3.7e-07 29.7 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 AFZ80247.1 - 8e-06 25.6 0.1 1.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AFZ80247.1 - 2.8e-05 23.6 0.0 5.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 AFZ80247.1 - 0.00016 21.4 10.1 0.00016 21.4 7.0 2.1 2 0 0 2 2 2 1 Ring finger domain RRM_6 PF14259.1 AFZ80247.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 AFZ80247.1 - 0.014 15.1 4.2 0.035 13.8 2.9 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Nup35_RRM_2 PF14605.1 AFZ80247.1 - 0.019 14.7 0.1 0.042 13.6 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4 PF00097.20 AFZ80247.1 - 0.042 13.5 9.4 0.095 12.3 6.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 AFZ80247.1 - 0.61 9.6 3.7 4.5 6.8 0.1 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-ZPR1 PF03367.8 AFZ80248.1 - 3.6e-76 253.7 3.4 2.2e-39 134.2 1.8 3.1 2 1 0 2 2 2 2 ZPR1 zinc-finger domain Zn-ribbon_8 PF09723.5 AFZ80248.1 - 0.023 14.6 5.6 5.4 7.0 0.0 4.0 4 0 0 4 4 4 0 Zinc ribbon domain DASH_Duo1 PF08651.5 AFZ80248.1 - 0.074 12.6 0.1 0.91 9.1 0.0 2.5 1 1 1 2 2 2 0 DASH complex subunit Duo1 zf-DNL PF05180.7 AFZ80248.1 - 0.08 12.6 1.8 3.3 7.4 0.0 3.2 3 0 0 3 3 3 0 DNL zinc finger zinc_ribbon_5 PF13719.1 AFZ80248.1 - 0.62 9.6 4.3 20 4.8 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AFZ80248.1 - 1.1 9.0 5.0 17 5.1 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Sgf11 PF08209.6 AFZ80248.1 - 1.2 8.5 6.6 11 5.4 0.1 3.1 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) DUF2428 PF10350.4 AFZ80249.1 - 3.5e-22 78.6 0.3 5.7e-21 74.6 0.1 2.4 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 AFZ80249.1 - 0.00078 19.3 0.9 1.4 9.1 0.0 4.5 3 0 0 3 3 3 2 HEAT repeat zf-DHHC PF01529.15 AFZ80251.1 - 5e-32 110.6 6.4 6.4e-32 110.3 4.4 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.2 AFZ80251.1 - 4 7.3 8.3 7.3 6.4 5.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon RRM_1 PF00076.17 AFZ80252.1 - 3.2e-11 42.6 0.0 4.7e-11 42.1 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ80252.1 - 3.3e-09 36.5 0.0 7.2e-09 35.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ80252.1 - 0.00028 20.6 0.0 0.0062 16.3 0.0 2.1 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TB2_DP1_HVA22 PF03134.14 AFZ80254.1 - 3.1e-12 46.0 6.0 7.6e-12 44.8 4.1 1.7 1 1 0 1 1 1 1 TB2/DP1, HVA22 family RNA_pol_Rpb2_4 PF04566.8 AFZ80255.1 - 0.041 13.6 0.1 0.16 11.7 0.1 2.0 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 4 GTP_EFTU PF00009.22 AFZ80256.1 - 1.4e-38 132.1 0.0 2.6e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 AFZ80256.1 - 5.7e-37 125.6 0.0 1.6e-36 124.2 0.0 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 AFZ80256.1 - 7.6e-11 41.9 3.4 1.6e-10 40.9 0.6 2.6 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AFZ80256.1 - 0.0013 18.6 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dak1_2 PF13684.1 AFZ80256.1 - 0.025 13.5 0.4 0.045 12.6 0.3 1.3 1 0 0 1 1 1 0 Dihydroxyacetone kinase family DUF3421 PF11901.3 AFZ80257.1 - 0.00023 20.8 3.9 0.13 11.9 0.2 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) DUF3921 PF13060.1 AFZ80257.1 - 1.2 9.0 3.7 15 5.5 0.1 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF3921) Ins_beta PF03488.9 AFZ80258.1 - 0.15 11.8 1.2 0.28 11.0 0.8 1.4 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type SipA PF09052.5 AFZ80259.1 - 0.0017 16.8 1.0 0.0019 16.6 0.7 1.0 1 0 0 1 1 1 1 Salmonella invasion protein A OAD_gamma PF04277.8 AFZ80259.1 - 0.042 14.2 0.4 0.065 13.6 0.0 1.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_60s PF00428.14 AFZ80259.1 - 0.077 13.4 0.0 0.097 13.0 0.0 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Mito_fiss_reg PF05308.6 AFZ80259.1 - 0.22 10.8 2.2 0.22 10.8 1.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 AFZ80259.1 - 1.6 7.9 8.0 1.9 7.7 5.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TRAPP PF04051.11 AFZ80260.1 - 1.3e-30 105.9 0.2 1.6e-30 105.6 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NOB1_Zn_bind PF08772.6 AFZ80261.1 - 2.2e-23 81.8 0.9 6.2e-23 80.4 0.7 1.8 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like TPM PF04536.9 AFZ80262.1 - 0.0001 22.1 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase UPF0054 PF02130.12 AFZ80263.1 - 8e-25 86.8 1.4 4.5e-12 45.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0054 DUF3591 PF12157.3 AFZ80264.1 - 3e-35 121.4 0.0 8.2e-31 106.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3591) Bromodomain PF00439.20 AFZ80264.1 - 7.7e-15 54.5 0.3 3e-14 52.6 0.2 2.0 1 0 0 1 1 1 1 Bromodomain zf-CCHC_6 PF15288.1 AFZ80264.1 - 0.0014 18.2 1.7 0.0014 18.2 1.2 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 AFZ80264.1 - 0.038 13.9 0.3 0.1 12.5 0.2 1.8 1 0 0 1 1 1 0 Zinc knuckle EMP24_GP25L PF01105.19 AFZ80265.1 - 1.8e-24 86.4 0.2 2.3e-24 86.1 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CarboxypepD_reg PF13620.1 AFZ80265.1 - 0.016 15.2 0.6 0.026 14.5 0.4 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Tubulin PF00091.20 AFZ80267.1 - 4.3e-67 226.0 0.0 5.9e-67 225.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AFZ80267.1 - 1.8e-47 160.4 0.4 3.6e-47 159.5 0.3 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain DNA_photolyase PF00875.13 AFZ80269.1 - 0.045 13.5 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 DNA photolyase Pdase_C33_assoc PF14756.1 AFZ80270.1 - 0.11 12.1 0.1 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 Peptidase_C33-associated domain MIP-T3 PF10243.4 AFZ80270.1 - 0.26 9.7 0.1 0.33 9.3 0.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Glutaredoxin PF00462.19 AFZ80272.1 - 1.8e-14 53.4 0.0 1.1e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_9 PF14595.1 AFZ80272.1 - 0.0007 19.1 0.0 0.00095 18.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.9 AFZ80272.1 - 0.025 14.8 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 AFZ80272.1 - 0.097 12.8 0.3 0.24 11.6 0.2 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Trypsin PF00089.21 AFZ80273.1 - 3.9e-18 65.8 0.1 6.7e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 AFZ80273.1 - 1.2e-13 51.1 0.2 2e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 AFZ80273.1 - 1e-11 44.5 2.2 2.9e-08 33.4 0.0 3.1 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.19 AFZ80273.1 - 0.058 13.5 0.1 3.4 7.9 0.0 2.5 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Peptidase_G2 PF11962.3 AFZ80273.1 - 0.16 11.1 0.0 9.4 5.2 0.0 2.3 2 0 0 2 2 2 0 Peptidase_G2, IMC autoproteolytic cleavage domain Ribosomal_L10 PF00466.15 AFZ80274.1 - 4.3e-15 55.4 0.4 1e-14 54.2 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Vps36_ESCRT-II PF11605.3 AFZ80276.1 - 0.021 14.6 0.1 0.069 12.9 0.0 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Mito_fiss_reg PF05308.6 AFZ80276.1 - 1.9 7.8 3.6 3.9 6.7 2.5 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator UCH PF00443.24 AFZ80277.1 - 9e-41 139.7 0.1 2e-40 138.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AFZ80277.1 - 1.1e-11 44.7 2.5 9.5e-10 38.3 1.7 3.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 AFZ80277.1 - 4e-11 42.8 0.0 4e-11 42.8 0.0 2.9 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 AFZ80277.1 - 1e-07 31.5 0.0 0.012 15.4 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain DUF3173 PF11372.3 AFZ80277.1 - 0.01 15.3 0.0 0.48 10.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) ubiquitin PF00240.18 AFZ80278.1 - 2.6e-05 23.5 0.1 8.9e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.1 AFZ80278.1 - 0.00034 20.8 0.2 0.00086 19.5 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-like domain RRM_1 PF00076.17 AFZ80279.1 - 1e-15 57.1 0.0 2.3e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ80279.1 - 1.1e-13 50.9 0.0 2.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.3 AFZ80279.1 - 5.7e-10 39.1 0.2 1.1e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_5 PF13893.1 AFZ80279.1 - 3.1e-06 26.9 0.0 6.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fil_haemagg_2 PF13332.1 AFZ80280.1 - 0.005 16.6 2.1 0.0062 16.3 0.2 2.0 2 0 0 2 2 2 1 Haemagluttinin repeat FAINT PF04385.10 AFZ80281.1 - 1.3e-12 47.4 0.0 0.0032 17.2 0.1 3.6 3 1 0 3 3 3 3 Domain of unknown function, DUF529 Neur_chan_memb PF02932.11 AFZ80281.1 - 0.46 10.3 6.5 3.4 7.4 2.1 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ELM2 PF01448.19 AFZ80283.1 - 4.7e-06 27.1 1.2 6.5e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 ELM2 domain DnaJ PF00226.26 AFZ80285.1 - 1.4e-21 75.9 2.0 3.2e-21 74.8 1.4 1.6 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 AFZ80286.1 - 0.00016 21.2 0.0 0.018 14.6 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) bPH_5 PF10882.3 AFZ80286.1 - 0.023 14.4 0.3 0.064 13.0 0.1 1.8 1 1 1 2 2 2 0 Bacterial PH domain RRM_5 PF13893.1 AFZ80286.1 - 0.066 13.0 0.3 0.32 10.8 0.2 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EXOSC1 PF10447.4 AFZ80287.1 - 4.1e-17 61.9 0.2 6.3e-17 61.3 0.2 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 AFZ80287.1 - 7.9e-11 41.0 0.3 3.2e-10 39.1 0.0 2.2 3 0 0 3 3 3 1 Exosome complex exonuclease RRP4 N-terminal region Med10 PF09748.4 AFZ80288.1 - 2.6e-05 24.0 0.1 3.8e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF4455 PF14643.1 AFZ80288.1 - 0.0071 15.0 0.1 0.46 9.0 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4455) DUF4218 PF13960.1 AFZ80288.1 - 0.042 13.2 0.1 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) Nsp1_C PF05064.8 AFZ80288.1 - 0.3 10.7 2.4 0.94 9.1 0.3 2.2 2 1 0 2 2 2 0 Nsp1-like C-terminal region DUF3748 PF12566.3 AFZ80289.1 - 0.03 14.2 0.1 0.052 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) FAINT PF04385.10 AFZ80290.1 - 3e-48 161.5 50.0 3.7e-06 26.7 1.0 12.0 11 1 0 11 11 11 11 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80291.1 - 6.5e-49 163.6 40.0 9.5e-06 25.3 0.0 13.9 13 1 0 13 13 13 11 Domain of unknown function, DUF529 DUF2510 PF10708.4 AFZ80291.1 - 0.094 12.1 0.1 13 5.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) TruB-C_2 PF09157.6 AFZ80291.1 - 0.24 11.2 0.0 0.73 9.7 0.0 1.8 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal DUF346 PF03984.8 AFZ80291.1 - 0.25 10.8 0.5 10 5.7 0.0 2.7 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) Abhydrolase_6 PF12697.2 AFZ80292.1 - 5.2e-14 52.6 0.0 9.3e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FAINT PF04385.10 AFZ80292.1 - 1.6e-13 50.3 11.6 0.0027 17.5 0.0 5.6 5 0 0 5 5 5 4 Domain of unknown function, DUF529 Abhydrolase_5 PF12695.2 AFZ80292.1 - 3.4e-11 43.1 0.0 1.3e-10 41.1 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ80292.1 - 1.9e-09 37.2 0.5 1e-08 34.8 0.1 2.4 3 0 0 3 3 3 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 AFZ80292.1 - 0.0029 17.4 0.0 0.01 15.7 0.0 1.9 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 AFZ80292.1 - 0.012 15.1 0.0 0.056 12.9 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold UPF0565 PF10561.4 AFZ80292.1 - 0.021 13.7 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Abhydrolase_2 PF02230.11 AFZ80292.1 - 0.032 13.6 0.0 0.43 9.9 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 AFZ80292.1 - 0.095 11.9 0.5 5 6.2 0.0 2.7 2 1 0 2 2 2 0 Prolyl oligopeptidase family Rieske_2 PF13806.1 AFZ80293.1 - 4.9e-07 29.4 0.0 9.6e-07 28.4 0.0 1.5 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 AFZ80293.1 - 1.7e-05 24.2 0.2 2.7e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Membrane_bind PF14564.1 AFZ80293.1 - 0.036 14.2 0.1 2.9 8.0 0.0 2.6 2 1 0 2 2 2 0 Membrane binding Pkinase PF00069.20 AFZ80294.1 - 1.1e-46 159.1 0.1 2.6e-46 157.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ80294.1 - 3.5e-23 82.0 0.1 6.8e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NAD_Gly3P_dh_N PF01210.18 AFZ80295.1 - 1.3e-46 158.1 0.5 2.6e-46 157.2 0.3 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 AFZ80295.1 - 1.9e-43 147.7 0.0 5e-43 146.3 0.0 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus IlvN PF07991.7 AFZ80295.1 - 0.011 15.1 0.2 1.6 8.1 0.0 2.5 1 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 AFZ80295.1 - 0.02 15.1 0.0 0.063 13.5 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.12 AFZ80295.1 - 0.039 14.3 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FMO-like PF00743.14 AFZ80295.1 - 0.047 11.9 0.0 0.095 10.8 0.0 1.4 1 1 0 1 1 1 0 Flavin-binding monooxygenase-like AlaDh_PNT_C PF01262.16 AFZ80295.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 AFZ80295.1 - 0.16 11.1 0.1 0.72 8.9 0.0 1.9 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain U-box PF04564.10 AFZ80296.1 - 1.6e-22 79.2 0.1 5.2e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 U-box domain TPR_11 PF13414.1 AFZ80296.1 - 2.3e-19 68.8 4.6 4.4e-16 58.2 1.5 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 AFZ80296.1 - 9.4e-15 53.2 4.2 2.1e-06 27.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 AFZ80296.1 - 1.1e-12 46.9 5.9 2.9e-05 23.4 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 AFZ80296.1 - 2.8e-12 45.7 1.4 2.2e-07 30.5 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 AFZ80296.1 - 1.2e-11 44.5 1.8 2e-11 43.8 1.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 AFZ80296.1 - 8.1e-09 35.3 3.0 3.1e-06 27.0 0.4 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 AFZ80296.1 - 2.1e-07 31.4 0.1 0.009 16.6 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ80296.1 - 3.9e-07 29.3 4.3 0.00089 18.8 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 AFZ80296.1 - 6.1e-06 26.4 0.0 0.026 15.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 AFZ80296.1 - 5e-05 23.5 0.7 0.14 12.4 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 AFZ80296.1 - 0.00041 20.1 0.0 0.11 12.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 AFZ80296.1 - 0.00091 18.8 1.5 0.12 12.1 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 AFZ80296.1 - 0.007 15.4 0.5 0.011 14.8 0.3 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 AFZ80296.1 - 0.013 15.8 0.5 29 5.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SieB PF14163.1 AFZ80296.1 - 0.77 9.3 2.6 0.84 9.2 0.9 1.7 1 1 1 2 2 2 0 Superinfection exclusion protein B GTP1_OBG PF01018.17 AFZ80297.1 - 1.1e-43 148.5 5.9 1.9e-43 147.8 4.1 1.4 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 AFZ80297.1 - 2.5e-19 69.3 0.0 7e-19 67.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF1967 PF09269.6 AFZ80297.1 - 1.3e-16 59.9 0.0 3.9e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) Dynamin_N PF00350.18 AFZ80297.1 - 2.6e-07 30.5 0.8 4.1e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 AFZ80297.1 - 6.1e-07 28.8 0.0 2.4e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 AFZ80297.1 - 0.0019 17.3 0.1 0.011 14.8 0.1 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.1 AFZ80297.1 - 0.003 17.8 0.1 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 AFZ80297.1 - 0.02 15.3 0.0 0.24 11.8 0.0 2.8 2 1 0 2 2 2 0 Miro-like protein Arf PF00025.16 AFZ80297.1 - 0.059 12.6 0.0 0.92 8.7 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family KTI12 PF08433.5 AFZ80297.1 - 0.06 12.5 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 AFZ80297.1 - 0.083 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PAXIP1_C PF15364.1 AFZ80300.1 - 0.016 15.1 3.5 0.028 14.3 2.4 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein FAINT PF04385.10 AFZ80302.1 - 1.3e-45 153.1 0.1 2.7e-12 46.3 0.0 4.3 4 0 0 4 4 4 4 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80302.1 - 1.5e-14 54.1 5.1 0.021 14.3 0.1 4.1 4 0 0 4 4 4 4 Merozoite Antigen DUF3608 PF12257.3 AFZ80303.1 - 0.0069 15.3 0.0 0.0073 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) HALZ PF02183.13 AFZ80305.1 - 1.4e-06 27.8 7.1 0.044 13.4 0.0 3.2 2 1 1 3 3 3 2 Homeobox associated leucine zipper TMF_TATA_bd PF12325.3 AFZ80305.1 - 0.00096 18.8 1.4 0.023 14.3 1.0 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF3584 PF12128.3 AFZ80305.1 - 0.0042 14.5 0.1 0.0058 14.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) GAS PF13851.1 AFZ80305.1 - 0.011 14.9 1.3 0.082 12.0 0.5 2.2 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 AFZ80305.1 - 0.013 15.1 1.1 0.021 14.3 0.3 1.5 1 1 0 1 1 1 0 IncA protein Rootletin PF15035.1 AFZ80305.1 - 0.019 14.9 0.2 0.45 10.4 0.2 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF972 PF06156.8 AFZ80305.1 - 0.02 15.2 1.0 0.29 11.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 AFZ80305.1 - 0.021 15.1 0.8 0.58 10.4 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DUF2265 PF10023.4 AFZ80305.1 - 0.035 13.2 0.1 0.037 13.1 0.1 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) DivIC PF04977.10 AFZ80305.1 - 0.035 13.5 2.4 0.39 10.2 0.8 2.5 2 1 1 3 3 3 0 Septum formation initiator Spectrin PF00435.16 AFZ80305.1 - 0.041 14.1 1.4 0.15 12.3 0.4 2.1 2 0 0 2 2 2 0 Spectrin repeat Mnd1 PF03962.10 AFZ80305.1 - 0.043 13.4 0.4 0.077 12.6 0.3 1.5 1 1 0 1 1 1 0 Mnd1 family HalX PF08663.5 AFZ80305.1 - 0.044 13.7 3.6 0.31 11.0 1.0 2.6 2 1 0 2 2 2 0 HalX domain CALCOCO1 PF07888.6 AFZ80305.1 - 0.058 11.6 0.3 0.065 11.5 0.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like K-box PF01486.12 AFZ80305.1 - 0.062 13.0 0.7 4.9 7.0 0.1 2.9 2 1 1 3 3 3 0 K-box region Snapin_Pallidin PF14712.1 AFZ80305.1 - 0.072 13.4 2.1 0.2 11.9 0.3 2.2 2 1 0 2 2 2 0 Snapin/Pallidin Occludin_ELL PF07303.8 AFZ80305.1 - 0.095 13.4 0.7 0.24 12.1 0.4 1.8 2 0 0 2 2 2 0 Occludin homology domain Phage_GP20 PF06810.6 AFZ80305.1 - 0.1 12.0 4.0 0.32 10.4 2.7 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 Mod_r PF07200.8 AFZ80305.1 - 0.11 12.3 0.6 0.32 10.8 0.2 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Kinesin-relat_1 PF12711.2 AFZ80305.1 - 0.13 12.6 2.3 2.7 8.4 0.3 2.7 2 1 0 2 2 2 0 Kinesin motor CENP-F_leu_zip PF10473.4 AFZ80305.1 - 0.14 12.0 2.9 0.52 10.1 0.8 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 AFZ80305.1 - 0.17 9.5 3.1 0.73 7.4 2.3 1.7 1 1 0 1 1 1 0 Myosin tail Cep57_CLD_2 PF14197.1 AFZ80305.1 - 0.18 11.7 1.6 1.3 9.0 0.4 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ATG16 PF08614.6 AFZ80305.1 - 0.2 11.4 1.5 0.66 9.7 1.0 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF349 PF03993.7 AFZ80305.1 - 0.24 11.5 1.3 0.42 10.7 0.4 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) GrpE PF01025.14 AFZ80305.1 - 0.44 10.0 2.7 3.2 7.2 1.8 2.1 1 1 0 1 1 1 0 GrpE bZIP_1 PF00170.16 AFZ80305.1 - 0.79 9.7 6.1 4 7.4 0.7 3.1 2 2 1 3 3 3 0 bZIP transcription factor Tup_N PF08581.5 AFZ80305.1 - 0.85 9.8 4.3 10 6.3 0.5 3.1 1 1 2 3 3 3 0 Tup N-terminal Bap31 PF05529.7 AFZ80305.1 - 1.1 8.6 3.2 1.2 8.5 0.6 1.9 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Ribosomal_L10 PF00466.15 AFZ80306.1 - 5.1e-22 77.6 0.3 1.3e-21 76.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 AFZ80306.1 - 3.8e-19 68.8 9.7 6.9e-19 68.0 6.7 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L38e PF01781.13 AFZ80307.1 - 1.1e-28 98.7 1.1 1.2e-28 98.6 0.8 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Lactamase_B PF00753.22 AFZ80308.1 - 3.4e-22 79.0 0.0 4.3e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AFZ80308.1 - 1.5e-05 24.6 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2981 PF11200.3 AFZ80309.1 - 2e-40 138.8 7.7 7.2e-33 114.0 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2981) AAA PF00004.24 AFZ80310.1 - 4.4e-41 140.1 0.1 1.1e-40 138.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AFZ80310.1 - 2.3e-06 27.4 0.0 1.2e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AFZ80310.1 - 1.3e-05 25.2 0.1 0.0019 18.2 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 AFZ80310.1 - 2e-05 24.6 0.0 0.0001 22.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 AFZ80310.1 - 3.6e-05 22.9 0.1 8.7e-05 21.6 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 AFZ80310.1 - 0.00066 19.5 0.1 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AFZ80310.1 - 0.0013 17.9 0.2 0.017 14.2 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 AFZ80310.1 - 0.0022 17.6 0.3 0.0061 16.2 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 AFZ80310.1 - 0.0025 17.9 3.9 0.016 15.3 0.3 2.9 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 AFZ80310.1 - 0.0042 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AFZ80310.1 - 0.0065 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.11 AFZ80310.1 - 0.0066 15.6 0.2 0.017 14.3 0.0 1.7 2 0 0 2 2 2 1 PhoH-like protein AAA_17 PF13207.1 AFZ80310.1 - 0.018 15.8 0.0 0.056 14.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AFZ80310.1 - 0.029 13.4 0.1 0.059 12.4 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.1 AFZ80310.1 - 0.031 13.8 0.7 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 AFZ80310.1 - 0.047 13.1 0.1 0.39 10.1 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 AFZ80310.1 - 0.063 12.1 0.0 0.13 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CPT PF07931.7 AFZ80310.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.6 AFZ80310.1 - 0.089 12.3 0.1 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AFZ80310.1 - 0.1 12.2 0.3 1.4 8.5 0.0 2.3 1 1 0 2 2 2 0 NACHT domain KaiC PF06745.8 AFZ80310.1 - 0.17 10.9 2.4 0.19 10.8 0.0 2.2 3 0 0 3 3 3 0 KaiC DUF3510 PF12022.3 AFZ80311.1 - 3.2e-24 85.3 4.8 3.2e-24 85.3 3.3 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3510) Abi_C PF14355.1 AFZ80311.1 - 0.0088 15.9 0.0 0.042 13.7 0.0 2.2 1 0 0 1 1 1 1 Abortive infection C-terminus Med4 PF10018.4 AFZ80311.1 - 0.06 12.7 0.0 0.22 10.9 0.0 1.9 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Ufm1 PF03671.9 AFZ80312.1 - 4.1e-36 122.5 0.1 4.7e-36 122.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein RA PF00788.18 AFZ80312.1 - 0.061 13.8 0.0 0.12 12.8 0.0 1.5 1 1 1 2 2 2 0 Ras association (RalGDS/AF-6) domain SMC_N PF02463.14 AFZ80313.1 - 3.9e-45 153.7 17.1 1.7e-44 151.6 11.8 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AFZ80313.1 - 1.7e-24 86.1 0.0 5.3e-24 84.5 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 AFZ80313.1 - 1.2e-08 34.3 0.0 3.7e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 AFZ80313.1 - 4.4e-08 33.4 35.4 3e-05 24.1 7.0 5.2 3 2 1 4 4 4 2 AAA domain AAA_23 PF13476.1 AFZ80313.1 - 5.8e-05 23.5 39.6 5.8e-05 23.5 27.5 6.0 2 2 0 2 2 1 1 AAA domain AAA_22 PF13401.1 AFZ80313.1 - 0.0012 19.0 1.4 3.2 7.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain GAS PF13851.1 AFZ80313.1 - 0.0017 17.5 5.9 0.0017 17.5 4.1 7.4 3 2 4 7 7 6 1 Growth-arrest specific micro-tubule binding APG6 PF04111.7 AFZ80313.1 - 0.0028 16.7 4.9 0.0028 16.7 3.4 6.5 3 2 3 6 6 6 1 Autophagy protein Apg6 ABC_tran PF00005.22 AFZ80313.1 - 0.021 15.1 0.0 0.021 15.1 0.0 5.9 4 3 0 4 4 2 0 ABC transporter Reo_sigmaC PF04582.7 AFZ80313.1 - 0.15 11.2 34.4 0.91 8.6 0.0 5.3 3 2 1 4 4 4 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 AFZ80313.1 - 5.1 5.4 103.0 0.44 8.9 11.6 6.1 3 2 3 6 6 6 0 AAA domain RRM_1 PF00076.17 AFZ80314.1 - 3.4e-19 68.2 0.0 1e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ80314.1 - 6.9e-11 41.9 0.0 0.0002 21.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ80314.1 - 6.5e-10 38.7 0.0 1.6e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IL12p40_C PF10420.4 AFZ80314.1 - 0.023 14.8 0.9 0.04 14.0 0.1 1.7 2 0 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus WD40 PF00400.27 AFZ80315.1 - 0.00024 20.8 6.5 0.025 14.4 0.3 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat HEAT_2 PF13646.1 AFZ80316.1 - 8.1e-17 61.2 1.3 1.6e-05 25.1 0.0 6.7 5 2 0 6 6 6 3 HEAT repeats HEAT PF02985.17 AFZ80316.1 - 1.9e-14 52.3 8.0 0.0087 16.0 0.0 9.0 10 0 0 10 10 10 3 HEAT repeat Vac14_Fab1_bd PF12755.2 AFZ80316.1 - 1.2e-11 44.8 4.4 0.0042 17.4 0.0 5.9 3 1 3 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 AFZ80316.1 - 6.8e-07 29.5 8.3 0.029 14.8 0.0 8.6 8 3 4 12 12 12 1 HEAT-like repeat Arm PF00514.18 AFZ80316.1 - 0.00024 20.8 1.3 12 5.8 0.0 5.5 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 AFZ80316.1 - 0.0017 18.2 0.8 0.02 14.7 0.3 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF2435 PF10363.4 AFZ80316.1 - 0.031 14.1 3.3 0.17 11.7 0.0 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF2435) Hydrolase_3 PF08282.7 AFZ80318.1 - 2.5e-34 119.0 0.0 3.8e-34 118.3 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AFZ80318.1 - 7e-05 22.2 0.0 0.033 13.4 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 AFZ80318.1 - 0.029 14.5 0.1 0.04 14.0 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 AFZ80318.1 - 0.16 11.2 0.0 0.59 9.4 0.0 1.8 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Gin PF10764.4 AFZ80319.1 - 0.41 10.3 3.3 0.38 10.4 0.1 2.7 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin FAINT PF04385.10 AFZ80320.1 - 6.2e-32 109.2 0.5 4.6e-05 23.1 0.0 6.7 6 0 0 6 6 6 6 Domain of unknown function, DUF529 Tox-SHH PF15652.1 AFZ80320.1 - 0.00079 19.9 4.1 4.6 7.8 0.0 5.0 5 0 0 5 5 5 2 HNH/Endo VII superfamily toxin with a SHH signature GSH_synth_ATP PF03917.12 AFZ80321.1 - 2.1e-40 138.4 0.0 4e-28 98.0 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 AFZ80321.1 - 9.6e-12 44.9 0.7 7.9e-11 41.9 0.5 2.3 1 1 0 1 1 1 1 Eukaryotic glutathione synthase Prefoldin_2 PF01920.15 AFZ80323.1 - 2.7e-17 62.4 10.3 3.4e-17 62.1 7.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 AFZ80323.1 - 5.8e-05 22.7 3.4 0.00014 21.5 2.1 2.1 1 1 0 1 1 1 1 Prefoldin subunit DUF1409 PF07197.7 AFZ80323.1 - 0.0054 16.7 0.5 0.0054 16.7 0.3 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1409) DUF948 PF06103.6 AFZ80323.1 - 0.0071 16.1 1.1 0.0071 16.1 0.7 1.9 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) FliD_C PF07195.7 AFZ80323.1 - 0.022 14.0 3.6 0.026 13.8 2.5 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Prefoldin PF02996.12 AFZ80323.1 - 0.025 14.2 3.2 0.025 14.2 2.2 2.3 1 1 1 2 2 2 0 Prefoldin subunit Atg14 PF10186.4 AFZ80323.1 - 0.041 12.8 9.7 0.048 12.5 6.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4509 PF14970.1 AFZ80323.1 - 0.042 13.4 4.7 0.052 13.1 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) COG2 PF06148.6 AFZ80323.1 - 0.045 13.6 4.9 0.082 12.7 3.1 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TMP-TENI PF02581.12 AFZ80323.1 - 0.065 12.3 0.1 0.082 12.0 0.1 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI FlaC_arch PF05377.6 AFZ80323.1 - 0.069 13.0 2.5 0.26 11.2 1.6 2.1 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) MADF_DNA_bdg PF10545.4 AFZ80323.1 - 0.12 12.5 0.4 0.35 11.1 0.1 1.7 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like AAA_13 PF13166.1 AFZ80323.1 - 0.32 9.4 10.5 0.36 9.2 7.3 1.0 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 AFZ80323.1 - 0.39 10.5 6.1 0.8 9.5 4.2 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 AFZ80323.1 - 0.56 10.3 9.7 0.95 9.5 6.7 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 AFZ80323.1 - 0.62 9.8 11.3 2.3 8.0 7.9 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Sec34 PF04136.10 AFZ80323.1 - 0.65 9.6 5.6 0.11 12.2 1.2 1.6 2 0 0 2 2 2 0 Sec34-like family DUF1664 PF07889.7 AFZ80323.1 - 0.75 9.5 5.9 0.1 12.3 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.2 AFZ80323.1 - 0.76 9.6 11.6 0.2 11.4 5.3 1.8 1 1 1 2 2 2 0 Tropomyosin like Cortex-I_coil PF09304.5 AFZ80323.1 - 1.5 8.9 9.2 1.8 8.6 4.1 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil Spc24 PF08286.6 AFZ80323.1 - 1.8 8.2 12.0 0.73 9.5 2.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.10 AFZ80323.1 - 1.9 8.0 10.7 0.91 9.0 0.9 2.4 1 1 1 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.14 AFZ80323.1 - 1.9 6.2 6.3 3 5.5 4.3 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 AFZ80323.1 - 3.4 7.1 12.9 0.17 11.4 2.1 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 AFZ80323.1 - 5.4 6.8 14.9 0.096 12.4 3.4 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Dus PF01207.12 AFZ80325.1 - 1.9e-68 230.5 0.0 2.8e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 AFZ80325.1 - 0.021 14.0 0.1 0.075 12.2 0.1 1.8 1 1 0 1 1 1 0 Histidine biosynthesis protein LexA_DNA_bind PF01726.11 AFZ80326.1 - 0.096 12.2 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 LexA DNA binding domain Ndr PF03096.9 AFZ80326.1 - 0.15 10.4 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 Ndr family FAST_1 PF06743.10 AFZ80327.1 - 0.0027 17.3 1.4 0.18 11.5 0.0 3.4 2 1 1 3 3 3 1 FAST kinase-like protein, subdomain 1 GSH_synth_ATP PF03917.12 AFZ80328.1 - 5e-42 143.8 0.0 2.7e-30 105.1 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 AFZ80328.1 - 1.1e-08 35.0 0.1 5.2e-08 32.9 0.1 2.1 1 1 0 1 1 1 1 Eukaryotic glutathione synthase CGI-121 PF08617.5 AFZ80329.1 - 2.4e-19 69.5 0.3 2.9e-19 69.2 0.2 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 MORN PF02493.15 AFZ80330.1 - 2.6e-32 108.6 43.5 2e-05 24.0 0.2 13.0 13 0 0 13 13 13 9 MORN repeat Avl9 PF09794.4 AFZ80330.1 - 2.2e-26 92.2 0.1 4e-24 84.8 0.1 2.2 1 1 0 1 1 1 1 Transport protein Avl9 DENN PF02141.16 AFZ80330.1 - 7.8e-05 22.4 0.2 0.52 10.0 0.0 2.6 2 0 0 2 2 2 2 DENN (AEX-3) domain TCTP PF00838.12 AFZ80331.1 - 7.7e-43 146.3 0.5 8.9e-43 146.1 0.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Big_3 PF07523.7 AFZ80331.1 - 0.042 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) zf-MYND PF01753.13 AFZ80332.1 - 5.9e-11 42.0 13.2 1.2e-10 41.0 9.2 1.5 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.2 AFZ80332.1 - 0.021 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) GTP_EFTU PF00009.22 AFZ80333.1 - 3.6e-57 192.8 0.0 5.8e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AFZ80333.1 - 1.1e-35 121.8 0.1 1.9e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 AFZ80333.1 - 5.9e-29 99.7 0.1 1.2e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 AFZ80333.1 - 5.1e-27 93.5 0.0 5.6e-26 90.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AFZ80333.1 - 9.5e-14 51.2 0.0 2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AFZ80333.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase TGS PF02824.16 AFZ80334.1 - 4.3e-20 71.3 0.0 7.3e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 AFZ80334.1 - 1e-19 70.5 0.1 1.8e-19 69.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AFZ80334.1 - 6.4e-12 45.0 0.1 1.9e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AFZ80334.1 - 3.4e-06 26.9 0.3 0.021 14.6 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 AFZ80334.1 - 0.00028 21.3 0.0 0.00086 19.7 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 AFZ80334.1 - 0.0008 18.2 0.3 0.0017 17.2 0.1 1.6 2 0 0 2 2 2 1 ArgK protein AIG1 PF04548.11 AFZ80334.1 - 0.0033 16.5 0.1 0.0046 16.0 0.0 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 AFZ80334.1 - 0.0056 16.1 0.5 2.9 7.2 0.0 3.7 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AFZ80334.1 - 0.047 12.9 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TFIID_30kDa PF03540.8 AFZ80335.1 - 0.063 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit SET PF00856.23 AFZ80336.1 - 1.3e-13 51.6 0.1 6.1e-13 49.3 0.1 2.2 1 1 0 1 1 1 1 SET domain DUF4362 PF14275.1 AFZ80340.1 - 0.0035 17.3 0.3 0.074 13.1 0.0 2.4 1 1 2 3 3 3 1 Domain of unknown function (DUF4362) FAINT PF04385.10 AFZ80340.1 - 0.02 14.7 1.0 0.02 14.7 0.7 2.3 2 1 1 3 3 3 0 Domain of unknown function, DUF529 ABC_tran PF00005.22 AFZ80341.1 - 1.1e-31 109.9 0.0 2.4e-17 63.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_23 PF13476.1 AFZ80341.1 - 3e-06 27.7 2.7 0.024 14.9 0.5 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 AFZ80341.1 - 1.3e-05 25.3 12.5 0.021 14.7 0.1 4.9 6 0 0 6 6 5 2 AAA domain AAA_16 PF13191.1 AFZ80341.1 - 2.7e-05 24.2 0.1 0.047 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AFZ80341.1 - 5.1e-05 22.7 0.9 0.11 11.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 AFZ80341.1 - 0.00014 22.1 0.1 0.18 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 AFZ80341.1 - 0.00014 21.4 0.0 0.056 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AFZ80341.1 - 0.00015 22.5 0.0 0.12 13.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AFZ80341.1 - 0.00026 20.4 0.0 0.057 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 AFZ80341.1 - 0.0011 18.8 2.3 0.052 13.3 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF87 T2SE PF00437.15 AFZ80341.1 - 0.0015 17.4 0.2 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 AFZ80341.1 - 0.0016 17.6 0.1 0.23 10.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 AFZ80341.1 - 0.0024 17.3 0.1 0.73 9.2 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_15 PF13175.1 AFZ80341.1 - 0.0027 16.8 1.5 5.6 5.9 0.0 3.8 4 0 0 4 4 3 0 AAA ATPase domain UPF0079 PF02367.12 AFZ80341.1 - 0.0037 16.8 0.6 0.17 11.5 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 AFZ80341.1 - 0.0043 16.1 0.3 2.4 7.1 0.1 2.3 2 0 0 2 2 2 2 Zeta toxin ArgK PF03308.11 AFZ80341.1 - 0.0047 15.7 0.3 0.012 14.3 0.0 1.7 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 AFZ80341.1 - 0.006 16.7 0.0 2.7 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 AFZ80341.1 - 0.0065 15.7 0.3 0.17 11.1 0.1 2.6 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 AFZ80341.1 - 0.0075 15.9 0.4 2.2 7.8 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 AFZ80341.1 - 0.0083 15.8 0.8 3.3 7.5 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 AFZ80341.1 - 0.0089 15.7 0.3 1.2 8.8 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DnaB_C PF03796.10 AFZ80341.1 - 0.0096 14.8 0.0 2.9 6.7 0.0 2.3 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Miro PF08477.8 AFZ80341.1 - 0.012 16.0 0.1 4.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 AFZ80341.1 - 0.035 14.0 0.1 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 AFZ80341.1 - 0.049 13.4 0.3 3.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Dynamin family cobW PF02492.14 AFZ80341.1 - 0.052 12.9 1.3 7 6.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 AFZ80341.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.12 AFZ80341.1 - 0.062 12.8 0.1 10 5.5 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 AFZ80341.1 - 0.089 12.5 0.2 5.4 6.6 0.1 2.3 2 0 0 2 2 2 0 NTPase TrwB_AAD_bind PF10412.4 AFZ80341.1 - 0.098 11.2 0.3 4.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.17 AFZ80341.1 - 0.11 11.2 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.2 AFZ80341.1 - 0.12 11.8 0.4 8.6 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 AFZ80341.1 - 0.17 11.7 0.0 7 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.18 AFZ80341.1 - 0.47 9.8 29.2 0.0067 15.8 14.0 2.4 2 0 0 2 2 2 0 ABC transporter transmembrane region AAA_28 PF13521.1 AFZ80341.1 - 0.75 9.7 1.3 21 5.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain 2-oxoacid_dh PF00198.18 AFZ80343.1 - 4.2e-78 261.8 0.1 5.2e-78 261.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 AFZ80343.1 - 6.4e-17 60.9 0.3 1.2e-16 60.0 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Mito_fiss_reg PF05308.6 AFZ80343.1 - 0.11 11.8 5.4 0.17 11.2 3.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator S_layer_C PF05124.7 AFZ80344.1 - 0.062 12.9 0.6 0.086 12.4 0.4 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region Fz PF01392.17 AFZ80348.1 - 0.012 15.9 2.1 0.031 14.6 0.4 2.2 2 0 0 2 2 2 0 Fz domain Sugarporin_N PF11471.3 AFZ80348.1 - 0.42 10.3 4.6 0.11 12.1 0.6 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension ABC_tran PF00005.22 AFZ80350.1 - 4.1e-35 121.0 0.0 1.1e-34 119.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 AFZ80350.1 - 5e-30 104.8 1.4 7e-30 104.3 1.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 AFZ80350.1 - 1.2e-08 35.2 0.1 0.0012 18.8 0.1 2.5 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 AFZ80350.1 - 2.7e-07 30.0 0.3 4.7e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 AFZ80350.1 - 5.5e-06 27.1 0.0 0.00016 22.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 AFZ80350.1 - 0.0013 18.1 0.1 0.0033 16.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 AFZ80350.1 - 0.0016 18.5 0.2 0.013 15.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AFZ80350.1 - 0.0036 16.5 0.0 0.0071 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 AFZ80350.1 - 0.0048 16.7 0.0 0.015 15.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 AFZ80350.1 - 0.0061 15.2 0.3 0.047 12.2 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.1 AFZ80350.1 - 0.0062 16.5 0.1 0.041 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 AFZ80350.1 - 0.0065 16.3 0.0 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AFZ80350.1 - 0.0078 15.6 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_18 PF13238.1 AFZ80350.1 - 0.0087 16.3 0.0 0.027 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AFZ80350.1 - 0.013 14.9 0.0 0.3 10.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 AFZ80350.1 - 0.022 15.1 0.2 0.022 15.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 AFZ80350.1 - 0.024 13.7 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 AFZ80350.1 - 0.026 13.6 0.0 0.06 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.12 AFZ80350.1 - 0.029 14.1 0.0 0.093 12.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 AFZ80350.1 - 0.036 14.2 0.0 0.095 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_13 PF13166.1 AFZ80350.1 - 0.09 11.2 2.1 0.9 7.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 AFZ80350.1 - 0.096 12.3 0.1 0.24 11.0 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 AFZ80350.1 - 0.1 12.5 0.4 0.3 11.0 0.3 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 AFZ80350.1 - 0.22 11.4 0.1 0.5 10.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain Arrestin_N PF00339.24 AFZ80351.1 - 1.5e-06 28.1 0.2 3.7e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.5 AFZ80351.1 - 6e-06 25.5 1.6 0.0007 18.7 1.0 2.2 2 0 0 2 2 2 2 Rgp1 Arrestin_C PF02752.17 AFZ80351.1 - 0.003 17.6 0.9 1.8 8.7 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Laminin_G_3 PF13385.1 AFZ80352.1 - 5.4e-25 88.4 0.1 1.7e-24 86.8 0.0 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 AFZ80352.1 - 0.00012 22.1 0.1 0.00028 20.9 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain Thg1 PF04446.7 AFZ80354.1 - 1.4e-42 144.4 0.1 2.1e-42 143.9 0.1 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 AFZ80354.1 - 9.3e-41 138.3 0.1 1.8e-40 137.4 0.1 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain MBOAT PF03062.14 AFZ80355.1 - 1.5e-15 57.1 30.6 2.6e-15 56.3 21.2 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family IncA PF04156.9 AFZ80355.1 - 0.00059 19.4 5.0 0.00059 19.4 3.5 5.4 2 1 3 5 5 5 3 IncA protein HALZ PF02183.13 AFZ80355.1 - 0.041 13.5 28.3 1.1 9.0 0.9 5.7 5 0 0 5 5 5 0 Homeobox associated leucine zipper HCMV_UL139 PF12507.3 AFZ80355.1 - 0.13 12.4 8.2 4.1 7.5 2.3 3.3 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein Reo_sigmaC PF04582.7 AFZ80355.1 - 0.28 10.3 27.2 0.26 10.4 9.5 3.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein MBOAT_2 PF13813.1 AFZ80355.1 - 0.61 10.1 7.6 0.29 11.2 3.2 2.0 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family CENP-F_leu_zip PF10473.4 AFZ80355.1 - 4.1 7.2 65.3 0.94 9.3 6.8 5.2 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 AFZ80355.1 - 4.4 7.0 52.5 0.084 12.6 6.4 4.5 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) HlyD PF00529.15 AFZ80355.1 - 4.9 6.3 18.5 6.6 5.9 5.0 2.3 2 0 0 2 2 2 0 HlyD family secretion protein mRNA_triPase PF02940.10 AFZ80356.1 - 6.2e-39 133.9 0.2 1.6e-38 132.6 0.1 1.6 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain Pro_isomerase PF00160.16 AFZ80357.1 - 3e-49 167.2 0.2 3.7e-49 166.8 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CPSF_A PF03178.10 AFZ80358.1 - 7.8e-43 146.7 3.8 3.7e-32 111.6 0.3 3.5 3 0 0 3 3 3 3 CPSF A subunit region Utp21 PF04192.7 AFZ80359.1 - 1.5e-28 99.5 4.7 2.2e-28 98.9 3.2 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 AFZ80359.1 - 1.7e-06 27.6 11.8 0.0025 17.6 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat UTP15_C PF09384.5 AFZ80359.1 - 0.00019 21.1 0.1 0.00042 20.0 0.1 1.5 1 0 0 1 1 1 1 UTP15 C terminal PQQ_2 PF13360.1 AFZ80359.1 - 0.11 11.8 0.0 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain Cpn60_TCP1 PF00118.19 AFZ80360.1 - 2.6e-138 461.6 19.6 3e-138 461.4 13.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CReP_N PF10472.4 AFZ80360.1 - 0.013 14.2 0.2 0.02 13.6 0.1 1.1 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor WD40 PF00400.27 AFZ80361.1 - 1.2e-07 31.3 1.7 0.031 14.1 0.1 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat zf-CCCH PF00642.19 AFZ80361.1 - 0.016 14.9 1.6 0.016 14.9 1.1 2.4 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 AFZ80363.1 - 1.7e-14 53.1 0.0 2.9e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ80363.1 - 8.5e-08 32.0 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ80363.1 - 0.0022 17.8 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_14 PF13428.1 AFZ80364.1 - 8.8e-05 22.8 0.0 21 6.1 0.0 4.1 4 1 0 4 4 4 3 Tetratricopeptide repeat Suf PF05843.9 AFZ80364.1 - 0.0029 17.3 7.9 0.069 12.8 0.1 3.7 1 1 2 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 AFZ80364.1 - 0.018 15.3 0.0 34 4.8 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF1477 PF07346.6 AFZ80364.1 - 0.036 14.1 0.2 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1477) S1 PF00575.18 AFZ80365.1 - 8.3e-19 67.4 15.4 1.5e-12 47.3 0.2 5.4 5 1 0 5 5 5 3 S1 RNA binding domain Ten1 PF12658.2 AFZ80365.1 - 0.053 13.2 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Telomere capping, CST complex subunit PCI PF01399.22 AFZ80366.1 - 5.2e-05 23.5 1.5 0.00036 20.7 0.0 3.2 3 0 0 3 3 3 1 PCI domain DUF3177 PF11375.3 AFZ80366.1 - 0.021 14.2 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) Dynein_light PF01221.13 AFZ80367.1 - 3.9e-41 138.9 1.1 4.5e-41 138.7 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 HTH_33 PF13592.1 AFZ80367.1 - 0.019 14.4 0.0 0.044 13.3 0.0 1.6 1 1 0 1 1 1 0 Winged helix-turn helix Ground-like PF04155.13 AFZ80367.1 - 0.11 12.8 0.1 0.16 12.2 0.0 1.4 1 1 0 1 1 1 0 Ground-like domain RNA_pol_Rpb8 PF03870.10 AFZ80368.1 - 1e-33 116.4 0.2 1.2e-33 116.2 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RBB1NT PF08169.6 AFZ80368.1 - 0.11 12.4 0.1 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RBB1NT (NUC162) domain TnpW PF14202.1 AFZ80369.1 - 0.05 13.2 0.6 0.55 9.8 0.0 2.2 2 0 0 2 2 2 0 Transposon-encoded protein TnpW ATP-synt_E_2 PF08112.6 AFZ80369.1 - 0.072 13.1 0.2 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 ATP synthase epsilon subunit Sof1 PF04158.9 AFZ80370.1 - 2.7e-27 94.5 7.0 4.4e-27 93.9 4.9 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.27 AFZ80370.1 - 1.7e-26 91.0 19.8 6.3e-06 25.8 0.1 7.0 7 1 0 7 7 7 5 WD domain, G-beta repeat HECT PF00632.20 AFZ80372.1 - 1.5e-94 316.7 0.1 6.2e-94 314.7 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 AFZ80372.1 - 1.1e-68 231.7 0.6 1.1e-68 231.7 0.4 3.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 AFZ80372.1 - 4.4e-35 121.5 14.3 4.4e-35 121.5 9.9 2.8 2 1 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 AFZ80372.1 - 1.3e-20 73.3 1.5 4.2e-20 71.6 0.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4414) EF-hand_1 PF00036.27 AFZ80373.1 - 2.1e-25 86.0 13.7 1.4e-06 27.1 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 AFZ80373.1 - 5.4e-24 81.8 10.5 1.3e-06 27.7 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 AFZ80373.1 - 9.1e-23 80.1 11.3 2.2e-11 43.6 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 AFZ80373.1 - 6e-21 73.8 19.1 2.3e-09 36.7 1.1 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 AFZ80373.1 - 2.2e-13 48.8 12.2 0.0017 17.6 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 AFZ80373.1 - 2.8e-12 46.3 0.3 6.1e-06 26.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 AFZ80373.1 - 0.00021 20.9 6.5 0.16 11.7 0.0 3.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 AFZ80373.1 - 0.0036 17.0 0.2 2.9 7.6 0.0 2.7 2 1 1 3 3 3 2 Tellurite resistance protein TerB DUF592 PF04574.8 AFZ80373.1 - 0.08 12.4 0.9 0.4 10.2 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF592) DUF1636 PF07845.6 AFZ80373.1 - 0.12 12.5 0.0 10 6.3 0.0 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1636) Tubulin_3 PF14881.1 AFZ80373.1 - 0.21 11.0 3.2 0.3 10.5 1.9 1.4 1 1 0 1 1 1 0 Tubulin domain Toprim_2 PF13155.1 AFZ80373.1 - 0.32 11.3 3.8 32 4.9 0.0 3.2 1 1 3 4 4 4 0 Toprim-like DUF2220 PF09983.4 AFZ80374.1 - 3.5e-08 32.8 0.0 5.8e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) DUF2399 PF09664.5 AFZ80374.1 - 2.4e-05 24.2 0.0 4.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) SHS2_Rpb7-N PF03876.12 AFZ80375.1 - 2.1e-15 56.6 0.1 3.4e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 AFZ80375.1 - 2.2e-09 37.2 0.0 4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain AhpC-TSA PF00578.16 AFZ80376.1 - 1.6e-18 66.5 0.0 2e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AFZ80376.1 - 5.4e-14 51.9 0.0 6.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin ABC_tran PF00005.22 AFZ80377.1 - 1.6e-29 102.9 0.0 4.5e-16 59.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 AFZ80377.1 - 9.8e-06 25.6 0.1 0.027 14.4 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AFZ80377.1 - 9.8e-05 21.8 1.3 0.12 11.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AFZ80377.1 - 0.00022 21.5 2.0 0.27 11.5 0.3 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 AFZ80377.1 - 0.00036 20.1 0.2 0.069 12.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AFZ80377.1 - 0.00041 21.1 0.0 0.22 12.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 AFZ80377.1 - 0.00071 18.4 0.4 0.002 16.9 0.0 1.8 2 0 0 2 2 2 1 ArgK protein Arch_ATPase PF01637.13 AFZ80377.1 - 0.00097 18.8 0.1 1.9 8.1 0.1 3.2 2 1 0 2 2 2 1 Archaeal ATPase T2SE PF00437.15 AFZ80377.1 - 0.0014 17.6 0.9 0.51 9.1 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MobB PF03205.9 AFZ80377.1 - 0.0014 18.3 0.5 0.8 9.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 AFZ80377.1 - 0.0015 18.0 0.0 0.27 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AFZ80377.1 - 0.0018 17.5 0.1 0.21 10.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 AFZ80377.1 - 0.0032 17.9 0.1 4.3 7.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 AFZ80377.1 - 0.0037 17.2 8.8 0.065 13.1 0.0 4.0 6 0 0 6 6 4 2 AAA domain AAA_22 PF13401.1 AFZ80377.1 - 0.0037 17.4 0.0 3.7 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 AFZ80377.1 - 0.0047 16.0 0.2 3.6 6.5 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 AFZ80377.1 - 0.0047 17.2 0.1 0.99 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 AFZ80377.1 - 0.0078 15.3 0.2 3.3 6.7 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 AFZ80377.1 - 0.0097 15.6 0.7 4.5 7.1 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 AFZ80377.1 - 0.011 15.2 0.1 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family SMC_N PF02463.14 AFZ80377.1 - 0.024 13.8 0.3 0.35 10.0 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 AFZ80377.1 - 0.046 13.3 0.6 1.2 8.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 AFZ80377.1 - 0.049 13.4 1.4 0.13 12.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 AFZ80377.1 - 0.056 13.4 0.2 0.41 10.6 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 AFZ80377.1 - 0.062 12.9 1.5 9.4 5.8 0.0 2.8 3 0 0 3 3 2 0 NACHT domain AAA_33 PF13671.1 AFZ80377.1 - 0.092 12.6 0.1 6 6.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.17 AFZ80377.1 - 0.098 11.5 0.3 0.96 8.2 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain cobW PF02492.14 AFZ80377.1 - 0.12 11.7 1.9 11 5.3 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 AFZ80377.1 - 0.2 10.2 0.4 6.4 5.2 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FAINT PF04385.10 AFZ80378.1 - 3.7e-05 23.4 0.1 0.14 12.0 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80378.1 - 0.004 16.6 1.0 0.023 14.1 0.7 2.0 1 1 0 1 1 1 1 Merozoite Antigen DUF2861 PF11060.3 AFZ80378.1 - 0.0097 15.2 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2861) DUF3548 PF12068.3 AFZ80378.1 - 0.096 11.9 0.1 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) Rsm22 PF09243.5 AFZ80381.1 - 2.4e-66 223.5 0.0 4.2e-66 222.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Acyltransferase PF01553.16 AFZ80382.1 - 1e-15 57.3 0.0 4.9e-15 55.1 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase RseC_MucC PF04246.7 AFZ80382.1 - 0.017 14.7 2.7 0.79 9.2 0.0 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Fis1_TPR_C PF14853.1 AFZ80383.1 - 2.1e-13 49.9 5.2 2.8e-07 30.2 0.5 2.4 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.1 AFZ80383.1 - 2.9e-12 46.0 3.8 5e-07 29.2 2.9 2.6 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AFZ80383.1 - 2.5e-11 42.6 8.9 0.00052 19.5 0.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 AFZ80383.1 - 6.9e-11 41.2 4.6 0.0056 16.4 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 AFZ80383.1 - 2.2e-09 37.5 1.9 5.6e-07 29.8 0.2 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AFZ80383.1 - 4.7e-07 30.3 0.0 0.00051 20.6 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ80383.1 - 2.7e-06 26.7 8.1 0.013 15.2 0.7 3.5 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AFZ80383.1 - 6e-06 25.6 0.3 0.63 9.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AFZ80383.1 - 2.3e-05 24.4 1.5 0.00011 22.3 1.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 AFZ80383.1 - 7.2e-05 23.0 0.0 0.54 11.0 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 AFZ80383.1 - 9.3e-05 22.2 1.0 0.0052 16.6 0.3 2.8 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.1 AFZ80383.1 - 0.00013 21.8 2.5 0.0035 17.2 1.3 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 AFZ80383.1 - 0.00013 22.1 0.5 2.5 8.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 AFZ80383.1 - 0.0036 17.3 4.1 7.3 7.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat Clathrin PF00637.15 AFZ80383.1 - 0.024 14.2 0.8 0.052 13.1 0.3 1.7 1 1 1 2 2 2 0 Region in Clathrin and VPS TPR_10 PF13374.1 AFZ80383.1 - 0.12 12.2 0.1 14 5.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF788 PF05620.6 AFZ80384.1 - 4.6e-17 62.4 1.0 4.6e-16 59.1 0.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF788) TB2_DP1_HVA22 PF03134.14 AFZ80384.1 - 0.25 11.0 4.2 0.17 11.6 0.7 2.0 2 1 0 2 2 2 0 TB2/DP1, HVA22 family Metallophos PF00149.23 AFZ80385.1 - 1.8e-31 109.0 0.9 3e-31 108.3 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.1 AFZ80385.1 - 8.4e-23 80.2 5.1 5.3e-07 29.6 0.4 5.2 5 1 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.27 AFZ80385.1 - 5.1e-20 69.1 2.5 0.0061 15.7 0.0 7.4 7 0 0 7 7 7 5 EF hand EF-hand_8 PF13833.1 AFZ80385.1 - 1.2e-13 50.3 3.5 0.00027 20.4 0.1 5.1 4 2 1 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.1 AFZ80385.1 - 2.8e-12 45.4 4.9 0.46 10.5 0.0 7.9 8 0 0 8 8 8 3 EF-hand domain CAP_GLY PF01302.20 AFZ80385.1 - 1.2e-06 28.1 0.1 2.5e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 CAP-Gly domain EF-hand_5 PF13202.1 AFZ80385.1 - 0.0011 18.1 3.4 5.1 6.6 0.0 5.5 5 0 0 5 5 5 1 EF hand PPP5 PF08321.7 AFZ80385.1 - 0.0056 16.6 0.5 0.26 11.3 0.0 3.1 3 0 0 3 3 3 1 PPP5 TPR repeat region IQ PF00612.22 AFZ80385.1 - 0.008 15.7 0.1 0.019 14.5 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Phosphodiest PF01663.17 AFZ80390.1 - 0.00052 19.4 0.1 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 AFZ80390.1 - 0.0044 16.2 0.1 0.029 13.5 0.0 2.2 2 0 0 2 2 2 1 Sulfatase Hexapep PF00132.19 AFZ80392.1 - 1.4e-08 33.8 10.0 0.00072 18.9 0.2 3.7 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AFZ80392.1 - 1.5 8.4 7.6 3.3 7.3 1.5 2.9 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase Band_7 PF01145.20 AFZ80394.1 - 4.7e-24 85.2 0.6 7.4e-24 84.6 0.2 1.5 1 1 1 2 2 2 1 SPFH domain / Band 7 family Med2 PF11214.3 AFZ80394.1 - 0.091 12.7 1.3 0.18 11.8 0.9 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 Proteasome PF00227.21 AFZ80395.1 - 5.4e-33 113.8 0.0 6.9e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PB1 PF00564.19 AFZ80395.1 - 0.072 12.7 0.2 0.66 9.6 0.0 2.3 2 0 0 2 2 2 0 PB1 domain TPR_16 PF13432.1 AFZ80396.1 - 3e-07 30.9 0.6 1.6 9.4 0.0 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat Apc3 PF12895.2 AFZ80396.1 - 8.6e-07 29.0 19.8 0.06 13.4 0.4 6.4 5 1 2 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 AFZ80396.1 - 1.1e-06 28.8 4.9 1.1 9.6 0.0 5.8 6 1 2 8 8 8 2 Tetratricopeptide repeat SRP72 PF08492.7 AFZ80396.1 - 5.3e-06 26.7 6.1 5.3e-06 26.7 4.2 2.7 3 0 0 3 3 2 1 SRP72 RNA-binding domain TPR_14 PF13428.1 AFZ80396.1 - 1.5e-05 25.1 0.4 12 6.8 0.0 6.3 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 AFZ80396.1 - 5.1e-05 22.8 17.0 1.9 8.2 0.2 7.2 7 1 0 7 7 7 1 TPR repeat TPR_12 PF13424.1 AFZ80396.1 - 0.0005 19.9 12.8 7.4 6.5 0.2 6.1 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 AFZ80396.1 - 0.01 16.1 0.0 0.49 10.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 AFZ80396.1 - 0.011 15.5 23.3 4.1 7.5 0.3 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 AFZ80396.1 - 0.032 14.7 10.6 27 5.4 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.15 AFZ80396.1 - 0.18 11.8 5.1 4.4 7.4 0.0 5.2 6 0 0 6 6 6 0 PPR repeat PPR_2 PF13041.1 AFZ80396.1 - 0.19 11.7 4.1 20 5.2 0.0 4.3 6 0 0 6 6 6 0 PPR repeat family TPR_17 PF13431.1 AFZ80396.1 - 0.31 11.3 6.4 3 8.2 0.0 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ80396.1 - 8.8 6.3 21.8 2.6 8.0 0.1 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat MutS_V PF00488.16 AFZ80397.1 - 3.1e-80 268.9 0.4 5.2e-80 268.2 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.15 AFZ80397.1 - 2.9e-33 114.2 0.2 1.1e-32 112.3 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.13 AFZ80397.1 - 5e-33 114.6 3.9 5.8e-33 114.4 0.8 2.4 3 0 0 3 3 3 1 MutS domain III AAA_23 PF13476.1 AFZ80397.1 - 0.012 15.9 0.0 0.012 15.9 0.0 3.6 3 2 0 3 3 3 0 AAA domain AAA_14 PF13173.1 AFZ80397.1 - 0.012 15.4 0.5 0.15 11.9 0.0 3.0 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 AFZ80397.1 - 0.026 13.1 0.1 0.051 12.1 0.1 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class MutS_II PF05188.12 AFZ80397.1 - 0.026 14.5 0.2 0.17 11.9 0.0 2.6 2 0 0 2 2 2 0 MutS domain II AAA_29 PF13555.1 AFZ80397.1 - 0.036 13.5 0.0 0.13 11.7 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 AFZ80397.1 - 0.047 13.8 0.0 0.39 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 AFZ80397.1 - 0.062 13.2 0.4 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain CLTH PF10607.4 AFZ80398.1 - 3.6e-24 85.0 0.4 4.8e-24 84.7 0.3 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DNA_PPF PF02916.10 AFZ80398.1 - 0.025 14.6 0.6 0.054 13.5 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase processivity factor Utp12 PF04003.7 AFZ80399.1 - 2.8e-15 56.1 0.5 4e-15 55.6 0.4 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Ribosomal_L18p PF00861.17 AFZ80400.1 - 1.7e-06 28.2 0.2 2.9e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_S11 PF00411.14 AFZ80400.1 - 1e-05 25.6 0.5 1.9e-05 24.7 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 FAINT PF04385.10 AFZ80401.1 - 1e-43 147.0 29.0 5.5e-08 32.5 0.9 8.7 8 0 0 8 8 8 8 Domain of unknown function, DUF529 Pollen_allerg_1 PF01357.16 AFZ80401.1 - 0.037 13.8 0.1 4.7 7.0 0.1 3.4 3 0 0 3 3 3 0 Pollen allergen Lactamase_B_2 PF12706.2 AFZ80402.1 - 9.3e-11 41.6 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AFZ80402.1 - 3.6e-09 36.5 0.0 5.2e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Cpn10 PF00166.16 AFZ80403.1 - 1.5e-27 95.3 0.0 1.7e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pro_isomerase PF00160.16 AFZ80404.1 - 2.7e-21 76.4 0.0 3.9e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UCR_6-4kD PF08997.5 AFZ80404.1 - 0.11 12.2 0.2 0.32 10.7 0.1 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein NifU_N PF01592.11 AFZ80405.1 - 1.1e-46 157.9 0.1 1.2e-46 157.7 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain RNase_P_Rpp14 PF01900.14 AFZ80406.1 - 1.9e-12 47.0 0.3 2.3e-12 46.7 0.2 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family UFD1 PF03152.9 AFZ80407.1 - 1.9e-10 40.1 0.0 2.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 GAS PF13851.1 AFZ80409.1 - 0.0081 15.3 0.6 0.017 14.3 0.4 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding 6PGD PF00393.14 AFZ80410.1 - 3.6e-77 259.4 0.1 7.7e-77 258.3 0.1 1.5 1 1 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 AFZ80410.1 - 4.4e-32 111.1 0.0 8.4e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AFZ80410.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Actin PF00022.14 AFZ80411.1 - 3.5e-51 173.8 0.0 2.8e-50 170.9 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AFZ80411.1 - 0.0004 19.0 0.1 0.18 10.3 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF2164 PF09932.4 AFZ80411.1 - 0.0044 16.7 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2164) MCPsignal PF00015.16 AFZ80413.1 - 0.033 13.7 0.2 0.055 13.0 0.2 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Alg14 PF08660.6 AFZ80414.1 - 1.4e-35 122.7 0.0 2e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Mid2 PF04478.7 AFZ80414.1 - 0.067 12.6 0.1 0.098 12.0 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MMR_HSR1 PF01926.18 AFZ80415.1 - 3.6e-16 59.1 0.0 5.5e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AFZ80415.1 - 0.00014 21.3 0.0 0.067 12.6 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 AFZ80415.1 - 0.00019 20.7 0.0 0.19 11.0 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 AFZ80415.1 - 0.00032 19.9 0.0 0.00072 18.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 AFZ80415.1 - 0.0007 19.4 0.0 0.26 11.1 0.1 2.3 1 1 1 2 2 2 2 Dynamin family MobB PF03205.9 AFZ80415.1 - 0.019 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 AFZ80415.1 - 0.044 12.9 0.0 0.14 11.3 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 AFZ80415.1 - 0.078 13.4 0.0 0.23 11.9 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein Ribosomal_L13e PF01294.13 AFZ80417.1 - 4.8e-50 169.5 2.4 6.5e-50 169.0 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e DUF2453 PF10507.4 AFZ80417.1 - 0.17 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) Ribosomal_S9 PF00380.14 AFZ80418.1 - 1.4e-34 118.9 0.3 1.6e-34 118.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 ATP-synt PF00231.14 AFZ80419.1 - 1.3e-81 274.1 3.7 1.5e-81 273.9 2.6 1.0 1 0 0 1 1 1 1 ATP synthase WD40 PF00400.27 AFZ80420.1 - 9.2e-32 107.7 9.7 3.7e-11 42.4 0.2 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 AFZ80420.1 - 0.0021 17.7 0.1 0.18 11.4 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 AFZ80420.1 - 0.009 14.1 0.8 0.71 7.9 0.0 2.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 LisH PF08513.6 AFZ80420.1 - 0.033 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 LisH Nucleoporin_N PF08801.6 AFZ80420.1 - 0.27 9.9 3.2 1.8 7.2 0.1 3.3 1 1 2 4 4 4 0 Nup133 N terminal like Ndc80_HEC PF03801.8 AFZ80421.1 - 6.8e-21 74.3 0.1 1.6e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family Apolipoprotein PF01442.13 AFZ80421.1 - 0.004 16.6 7.4 0.0099 15.4 0.6 2.6 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain His_Phos_1 PF00300.17 AFZ80421.1 - 0.016 15.3 0.3 0.04 13.9 0.2 1.7 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) DUF1192 PF06698.6 AFZ80421.1 - 0.15 11.9 5.6 1.1 9.1 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Fez1 PF06818.10 AFZ80421.1 - 0.25 11.3 19.3 0.037 14.0 1.2 3.3 3 0 0 3 3 3 0 Fez1 DivIC PF04977.10 AFZ80421.1 - 0.51 9.8 0.0 0.51 9.8 0.0 5.4 3 3 1 5 5 5 0 Septum formation initiator DUF4140 PF13600.1 AFZ80421.1 - 0.55 10.6 11.6 24 5.4 0.1 4.6 2 2 3 5 5 5 0 N-terminal domain of unknown function (DUF4140) Reo_sigmaC PF04582.7 AFZ80421.1 - 0.73 8.9 19.3 0.29 10.2 3.2 3.3 1 1 3 4 4 4 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 AFZ80421.1 - 0.76 9.6 33.1 6.3 6.6 5.1 4.3 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1515 PF07439.6 AFZ80421.1 - 1.5 8.6 5.4 39 4.1 0.1 3.9 3 1 2 5 5 5 0 Protein of unknown function (DUF1515) DUF883 PF05957.8 AFZ80421.1 - 8.6 6.8 6.6 1.7 9.0 0.8 2.8 4 1 0 4 4 2 0 Bacterial protein of unknown function (DUF883) FlgN PF05130.7 AFZ80421.1 - 9.9 6.4 24.3 1.9 8.7 5.5 4.0 2 2 1 3 3 3 0 FlgN protein Neur_chan_memb PF02932.11 AFZ80422.1 - 0.021 14.7 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rep_4 PF05797.6 AFZ80422.1 - 0.47 9.1 5.6 0.57 8.8 0.9 2.2 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) Cwf_Cwc_15 PF04889.7 AFZ80422.1 - 0.59 9.8 7.3 0.86 9.2 5.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1674 PF07896.7 AFZ80423.1 - 9.6e-07 28.9 1.1 2.1e-06 27.8 0.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Bromodomain PF00439.20 AFZ80425.1 - 1e-13 50.9 0.0 2.3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Fer4_17 PF13534.1 AFZ80426.1 - 5.1e-08 33.1 8.5 1.2e-07 31.9 5.9 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 AFZ80426.1 - 2e-05 24.5 8.0 4.9e-05 23.2 5.6 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 AFZ80426.1 - 0.00045 20.5 4.7 0.00045 20.5 3.3 2.7 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 AFZ80426.1 - 0.013 15.8 7.0 0.053 13.9 4.8 2.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 AFZ80426.1 - 0.014 15.2 9.5 0.036 13.8 6.6 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer2_3 PF13085.1 AFZ80427.1 - 7.1e-31 106.2 0.1 1e-30 105.8 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 AFZ80427.1 - 0.00059 19.5 1.3 0.0018 17.9 0.9 1.9 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Spermine_synth PF01564.12 AFZ80428.1 - 2.9e-05 23.1 0.0 8e-05 21.6 0.0 1.7 2 0 0 2 2 2 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 AFZ80428.1 - 0.0006 19.4 0.9 0.031 13.8 0.2 2.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AFZ80428.1 - 0.0035 16.7 0.1 1.9 7.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_26 PF13659.1 AFZ80428.1 - 0.0043 17.0 0.0 0.067 13.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AFZ80428.1 - 0.0065 16.9 0.1 0.35 11.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AFZ80428.1 - 0.052 14.0 0.0 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Helicase_C PF00271.26 AFZ80429.1 - 1e-09 38.0 0.1 3.3e-09 36.4 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AFZ80429.1 - 1.8e-09 37.2 0.1 2.7e-08 33.4 0.1 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 AFZ80429.1 - 0.00017 21.4 0.2 0.00017 21.4 0.2 3.1 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit RF-1 PF00472.15 AFZ80430.1 - 5.2e-16 58.4 1.0 9e-16 57.6 0.7 1.4 1 0 0 1 1 1 1 RF-1 domain BCIP PF13862.1 AFZ80431.1 - 3.2e-43 147.5 0.3 4e-43 147.1 0.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein CNH PF00780.17 AFZ80433.1 - 9.9e-12 44.8 2.1 4.1e-11 42.8 0.2 2.6 2 1 0 2 2 2 1 CNH domain Vps39_2 PF10367.4 AFZ80433.1 - 3.9e-09 36.6 0.0 1.3e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 FAINT PF04385.10 AFZ80435.1 - 6.2e-05 22.7 0.8 0.00015 21.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80436.1 - 1.5e-08 34.3 4.0 0.00049 19.8 0.0 3.8 3 0 0 3 3 3 3 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80437.1 - 6.8e-08 32.2 0.1 1.9e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 ABC_tran PF00005.22 AFZ80438.1 - 5.5e-31 107.6 0.0 2.8e-17 63.2 0.0 2.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AFZ80438.1 - 6.2e-08 32.9 2.2 0.0067 16.4 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 AFZ80438.1 - 3.7e-06 27.0 0.1 0.0056 16.6 0.0 2.6 3 0 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.1 AFZ80438.1 - 1.8e-05 25.1 1.8 0.18 12.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 AFZ80438.1 - 0.00018 20.3 0.2 0.00018 20.3 0.2 1.7 2 0 0 2 2 2 1 ArgK protein AAA_29 PF13555.1 AFZ80438.1 - 0.00019 20.9 1.4 0.17 11.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 AFZ80438.1 - 0.00023 20.6 0.1 0.17 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 AFZ80438.1 - 0.00025 20.6 0.6 0.039 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AFZ80438.1 - 0.00041 21.1 0.0 0.32 11.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AFZ80438.1 - 0.00042 20.6 0.3 0.37 11.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AFZ80438.1 - 0.0013 17.9 1.0 0.055 12.6 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 AFZ80438.1 - 0.0014 17.7 0.5 0.5 9.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin T2SE PF00437.15 AFZ80438.1 - 0.0048 15.8 0.5 2.7 6.8 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 AFZ80438.1 - 0.0069 16.8 0.3 4 7.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 AFZ80438.1 - 0.0098 15.3 0.7 2 7.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family SMC_N PF02463.14 AFZ80438.1 - 0.011 14.9 0.1 0.3 10.2 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MobB PF03205.9 AFZ80438.1 - 0.013 15.1 0.8 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 AFZ80438.1 - 0.015 14.9 1.5 0.47 10.0 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Fer4_NifH PF00142.13 AFZ80438.1 - 0.015 14.5 0.3 3.5 6.7 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF87 PF01935.12 AFZ80438.1 - 0.02 14.7 2.6 0.075 12.8 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 NB-ARC PF00931.17 AFZ80438.1 - 0.023 13.5 0.5 0.19 10.5 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF2791 PF10923.3 AFZ80438.1 - 0.025 13.1 0.0 0.27 9.8 0.0 2.1 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) AAA_22 PF13401.1 AFZ80438.1 - 0.055 13.6 0.5 14 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 AFZ80438.1 - 0.056 13.2 0.4 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 AFZ80438.1 - 0.056 13.3 0.3 4.8 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 AFZ80438.1 - 0.064 13.2 0.6 0.27 11.2 0.1 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 AFZ80438.1 - 0.076 12.6 1.7 5 6.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 AFZ80438.1 - 0.082 12.6 0.4 4.7 6.9 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 AFZ80438.1 - 0.16 11.7 3.4 5.1 6.9 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain SRP54 PF00448.17 AFZ80438.1 - 0.51 9.7 2.1 3.5 7.0 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain cobW PF02492.14 AFZ80438.1 - 0.56 9.6 3.2 13 5.2 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 AFZ80438.1 - 0.88 8.1 2.8 11 4.5 0.1 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Prenyltrans PF00432.16 AFZ80440.1 - 4.1e-19 67.8 5.4 8.8e-07 28.3 0.0 5.2 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AFZ80440.1 - 8.4e-14 51.9 0.0 1.8e-07 31.5 0.0 3.9 2 2 1 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 AFZ80440.1 - 0.0078 16.2 0.0 0.11 12.5 0.0 2.6 3 1 0 3 3 3 1 Prenyltransferase-like Rab5ip PF07019.7 AFZ80441.1 - 1.6e-10 40.9 3.1 2.1e-10 40.5 2.2 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Fer2 PF00111.22 AFZ80443.1 - 4.4e-10 39.1 1.9 5.9e-10 38.7 1.3 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NifU PF01106.12 AFZ80443.1 - 0.0027 17.4 0.1 0.006 16.3 0.1 1.6 1 0 0 1 1 1 1 NifU-like domain ABM PF03992.11 AFZ80444.1 - 0.0046 16.9 0.0 0.0067 16.4 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase PagL PF09411.5 AFZ80445.1 - 0.049 13.7 0.1 0.062 13.3 0.1 1.1 1 0 0 1 1 1 0 Lipid A 3-O-deacylase (PagL) Merozoite_SPAM PF07133.6 AFZ80446.1 - 0.11 12.3 10.4 0.13 12.1 7.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) FTA4 PF13093.1 AFZ80446.1 - 0.12 11.7 2.3 0.13 11.6 1.6 1.0 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GOLD_2 PF13897.1 AFZ80446.1 - 0.25 11.5 2.9 0.27 11.4 2.0 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF2890 PF11081.3 AFZ80446.1 - 5.2 7.0 8.6 5.6 6.9 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Polysacc_synt_C PF14667.1 AFZ80447.1 - 0.0027 17.5 18.2 0.017 14.8 2.6 2.3 1 1 1 2 2 2 2 Polysaccharide biosynthesis C-terminal domain DUF2613 PF11021.3 AFZ80447.1 - 0.02 14.5 2.8 5.1 6.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) TauE PF01925.14 AFZ80447.1 - 0.026 13.9 14.1 0.0059 16.0 7.6 1.4 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE PIRT PF15099.1 AFZ80447.1 - 0.076 12.2 5.3 0.02 14.0 1.6 1.6 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DUF202 PF02656.10 AFZ80447.1 - 2 8.6 10.8 3 8.1 2.8 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF202) DUF4231 PF14015.1 AFZ80447.1 - 2.6 8.0 4.9 1.1 9.2 0.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) AhpC-TSA PF00578.16 AFZ80448.1 - 8.2e-28 96.5 0.0 1.1e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AFZ80448.1 - 7.7e-12 44.9 0.0 1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 AFZ80448.1 - 1.3e-09 37.5 0.0 3e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin FAINT PF04385.10 AFZ80449.1 - 3e-05 23.7 0.0 0.048 13.4 0.0 2.9 2 1 1 3 3 3 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80449.1 - 5.7e-05 22.7 0.4 0.025 14.0 0.4 2.0 2 0 0 2 2 2 2 Merozoite Antigen DUF3787 PF12655.2 AFZ80449.1 - 0.1 12.3 0.1 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) Podoplanin PF05808.6 AFZ80450.1 - 0.036 13.6 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Podoplanin HisG PF01634.13 AFZ80450.1 - 0.054 13.0 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 ATP phosphoribosyltransferase DUF2951 PF11166.3 AFZ80450.1 - 0.83 9.5 6.8 1.6 8.6 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) AAA_23 PF13476.1 AFZ80454.1 - 0.0023 18.2 0.0 0.0078 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain Lipoprotein_20 PF13942.1 AFZ80454.1 - 0.19 11.2 1.6 0.33 10.4 1.1 1.3 1 0 0 1 1 1 0 YfhG lipoprotein MFS_1 PF07690.11 AFZ80455.1 - 3e-26 91.9 38.6 1.3e-24 86.5 18.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Baculo_11_kDa PF06143.6 AFZ80455.1 - 0.11 11.8 0.1 0.11 11.8 0.1 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family tRNA_edit PF04073.10 AFZ80456.1 - 1.4e-23 83.0 0.0 2.4e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain ProRS-C_1 PF09180.6 AFZ80456.1 - 6.2e-23 80.4 0.0 2e-22 78.8 0.0 1.9 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 AFZ80456.1 - 1.3e-19 69.8 0.1 8.1e-19 67.3 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.20 AFZ80456.1 - 1.7e-17 63.5 0.2 1e-16 60.9 0.1 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF1184 PF06683.6 AFZ80457.1 - 0.00017 21.2 3.3 0.00018 21.1 0.4 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1184) MACPF PF01823.14 AFZ80458.1 - 1.1e-41 142.8 1.5 2.6e-41 141.6 1.0 1.6 1 0 0 1 1 1 1 MAC/Perforin domain SRP19 PF01922.12 AFZ80459.1 - 5.7e-30 103.7 0.1 7.4e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein tRNA-synt_2b PF00587.20 AFZ80460.1 - 7.8e-29 100.4 0.0 1.8e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) IncA PF04156.9 AFZ80460.1 - 0.031 13.8 2.2 0.34 10.4 1.4 2.3 2 0 0 2 2 2 0 IncA protein Mpp10 PF04006.7 AFZ80461.1 - 8.2e-25 87.2 59.6 4.4e-24 84.8 41.3 2.1 1 1 0 1 1 1 1 Mpp10 protein MORN PF02493.15 AFZ80463.1 - 3.5e-84 271.7 95.5 8.3e-09 34.6 1.5 14.3 14 0 0 14 14 14 14 MORN repeat HCBP_related PF06594.6 AFZ80463.1 - 0.024 14.2 0.2 0.85 9.3 0.2 3.2 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain ARID PF01388.16 AFZ80464.1 - 2.6e-07 30.3 0.0 6.3e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF4517 PF15006.1 AFZ80464.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4517) UBX PF00789.15 AFZ80465.1 - 3.2e-14 52.7 0.0 6.5e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF1682 PF07946.9 AFZ80465.1 - 0.0063 15.3 2.4 0.009 14.8 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Thioredoxin_7 PF13899.1 AFZ80465.1 - 0.12 12.4 0.1 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like DUF1227 PF06777.6 AFZ80466.1 - 4.5e-49 165.9 0.1 8.7e-49 164.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 AFZ80466.1 - 2.5e-42 144.6 0.1 7.7e-42 143.0 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 AFZ80466.1 - 1.6e-31 109.0 1.7 1.3e-28 99.5 0.2 2.7 2 1 0 2 2 2 2 DEAD_2 ResIII PF04851.10 AFZ80466.1 - 9.4e-07 28.8 0.0 0.00022 21.1 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.24 AFZ80466.1 - 9.1e-05 22.0 0.0 0.05 13.1 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF3928 PF13065.1 AFZ80466.1 - 0.027 14.7 0.1 0.11 12.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3928) Myosin_tail_1 PF01576.14 AFZ80469.1 - 0.00023 19.0 32.1 0.00023 19.0 22.3 2.0 1 1 1 2 2 2 1 Myosin tail DUF3450 PF11932.3 AFZ80469.1 - 0.16 11.2 22.5 1.5 8.0 2.3 5.0 2 1 1 5 5 5 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.6 AFZ80469.1 - 0.17 11.8 0.2 0.17 11.8 0.1 6.3 5 1 3 8 8 8 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.16 AFZ80469.1 - 0.24 11.4 32.8 4 7.4 0.1 6.7 4 2 2 6 6 6 0 bZIP transcription factor Filament PF00038.16 AFZ80469.1 - 0.56 9.6 39.9 0.085 12.3 15.5 3.3 1 1 1 2 2 2 0 Intermediate filament protein DUF972 PF06156.8 AFZ80469.1 - 3.9 7.8 40.0 4.4 7.6 4.5 5.7 1 1 4 5 5 5 0 Protein of unknown function (DUF972) ATG16 PF08614.6 AFZ80469.1 - 4.4 7.0 40.5 0.6 9.8 19.1 3.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 AFZ80469.1 - 4.8 6.2 21.0 0.13 11.4 5.8 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein GAS PF13851.1 AFZ80469.1 - 7.1 5.7 48.7 1.4 8.0 16.5 4.8 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Spc97_Spc98 PF04130.8 AFZ80470.1 - 6.8e-41 140.1 17.0 8.1e-36 123.4 4.5 2.2 2 0 0 2 2 2 2 Spc97 / Spc98 family Peptidase_M16 PF00675.15 AFZ80471.1 - 7.2e-46 155.6 0.0 1.4e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AFZ80471.1 - 4.9e-37 127.3 0.0 4.9e-36 124.1 0.0 2.4 2 1 0 2 2 2 1 Peptidase M16 inactive domain TMF_TATA_bd PF12325.3 AFZ80472.1 - 0.035 13.8 0.1 0.039 13.6 0.1 1.0 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 AFZ80472.1 - 0.038 13.4 0.2 0.04 13.4 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator Sas10_Utp3 PF04000.10 AFZ80472.1 - 0.093 12.9 0.1 0.28 11.4 0.0 1.7 1 1 1 2 2 2 0 Sas10/Utp3/C1D family NYD-SP28 PF14772.1 AFZ80473.1 - 0.0093 16.0 2.7 0.01 15.9 1.9 1.1 1 0 0 1 1 1 1 Sperm tail Polysacc_synt_2 PF02719.10 AFZ80474.1 - 0.083 11.7 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pkinase PF00069.20 AFZ80476.1 - 2.8e-49 167.6 0.1 4.6e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ80476.1 - 7.3e-20 71.1 0.0 1.1e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FSH1 PF03959.8 AFZ80477.1 - 1.5e-41 142.2 0.0 2.3e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DAP3 PF10236.4 AFZ80477.1 - 2e-35 122.2 0.0 2.8e-34 118.4 0.0 2.5 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Abhydrolase_2 PF02230.11 AFZ80477.1 - 5.7e-05 22.6 0.0 0.00032 20.2 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 AFZ80477.1 - 6e-05 22.8 0.0 0.00015 21.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.1 AFZ80477.1 - 0.013 15.4 0.1 0.18 11.7 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain Abhydrolase_6 PF12697.2 AFZ80477.1 - 0.065 13.0 0.0 2 8.2 0.0 2.5 1 1 1 2 2 2 0 Alpha/beta hydrolase family AAA_22 PF13401.1 AFZ80477.1 - 0.079 13.0 0.0 3.6 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 AFZ80477.1 - 0.098 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 AFZ80477.1 - 0.098 11.6 0.1 0.19 10.6 0.1 1.5 1 1 0 1 1 1 0 KAP family P-loop domain DEAD PF00270.24 AFZ80478.1 - 2.1e-36 124.9 0.1 5.7e-36 123.5 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ80478.1 - 2.5e-22 78.5 0.2 7.1e-22 77.0 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ80478.1 - 1.2e-06 28.4 0.0 1.2e-06 28.4 0.0 2.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 AFZ80478.1 - 4.8e-05 22.3 0.0 0.00013 20.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 AFZ80478.1 - 0.018 14.3 0.0 0.08 12.2 0.0 2.0 2 1 1 3 3 3 0 SecA DEAD-like domain tRNA-synt_His PF13393.1 AFZ80479.1 - 2e-42 145.3 0.0 3.3e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 AFZ80479.1 - 1.4e-17 63.8 0.0 2.5e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AFZ80479.1 - 5.8e-10 38.9 0.2 1.3e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 AFZ80479.1 - 0.00014 20.7 0.7 0.001 17.9 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 AFZ80479.1 - 0.005 16.0 0.1 0.016 14.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) TctC PF03401.9 AFZ80479.1 - 0.072 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor WD40 PF00400.27 AFZ80482.1 - 6.2e-20 70.2 0.5 3.2e-05 23.6 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 AFZ80482.1 - 4.7e-13 48.8 0.0 1.3e-12 47.3 0.0 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 AFZ80483.1 - 2.7e-14 52.4 15.7 6.3e-05 22.6 0.9 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AFZ80483.1 - 0.089 11.5 4.1 1.4 7.5 0.3 2.8 1 1 0 2 2 2 0 Nup133 N terminal like SpoU_methylase PF00588.14 AFZ80484.1 - 1.7e-22 79.8 0.0 3e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF3746 PF12562.3 AFZ80484.1 - 0.91 9.4 4.9 2.5 7.9 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3746) IMCp PF12314.3 AFZ80486.1 - 1.3e-19 70.1 53.6 9.4e-13 48.1 17.0 2.1 1 1 1 2 2 2 2 Inner membrane complex protein ArfGap PF01412.13 AFZ80488.1 - 3.9e-40 136.2 0.0 7e-40 135.4 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF760 PF05542.6 AFZ80491.1 - 4.1e-34 116.6 0.0 7e-16 58.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF760) Suf PF05843.9 AFZ80492.1 - 2.5e-06 27.4 1.8 2.5e-06 27.4 1.2 3.7 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_11 PF13414.1 AFZ80492.1 - 0.054 13.1 1.2 6.4 6.5 0.0 2.5 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.1 AFZ80492.1 - 0.17 11.8 1.8 16 5.4 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ80492.1 - 0.49 10.3 3.0 4.2 7.3 0.5 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin PF00085.15 AFZ80493.1 - 1.6e-17 63.0 0.0 2.2e-16 59.3 0.0 2.8 3 1 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.1 AFZ80493.1 - 2.1e-16 60.2 3.8 2.1e-05 24.4 1.5 3.9 4 1 0 4 4 4 3 Thioredoxin-like domain Glutaredoxin PF00462.19 AFZ80493.1 - 0.0041 17.0 0.1 0.54 10.2 0.0 3.0 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin_2 PF13098.1 AFZ80493.1 - 0.0041 17.2 0.7 0.02 15.1 0.0 2.6 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AFZ80493.1 - 0.0082 16.1 0.0 0.028 14.4 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Myb_DNA-binding PF00249.26 AFZ80494.1 - 2.6e-11 43.3 0.0 5.8e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AFZ80494.1 - 1.6e-05 24.9 0.0 4.7e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 AFZ80494.1 - 0.00026 20.4 12.4 0.00064 19.1 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type HypA PF01155.14 AFZ80494.1 - 0.25 11.0 1.6 0.53 9.9 0.8 1.7 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family ThiF PF00899.16 AFZ80495.1 - 1.2e-37 128.8 0.4 8e-37 126.1 0.1 2.4 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 AFZ80495.1 - 2e-24 84.9 0.3 3.8e-24 84.0 0.2 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 AFZ80495.1 - 9.3e-19 66.5 0.7 2.5e-18 65.1 0.5 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 AFZ80495.1 - 1.1e-12 47.9 0.2 2.4e-12 46.7 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 AFZ80495.1 - 6.7e-07 29.4 0.0 2.6e-06 27.5 0.0 2.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 AFZ80495.1 - 0.00016 21.8 0.0 0.00049 20.3 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Saccharop_dh PF03435.13 AFZ80495.1 - 0.0026 16.8 0.1 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Pyr_redox PF00070.22 AFZ80495.1 - 0.0033 17.7 0.1 0.012 15.9 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 AFZ80495.1 - 0.012 15.6 0.1 0.035 14.0 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 AFZ80495.1 - 0.023 14.7 0.0 0.08 12.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 AFZ80495.1 - 0.044 13.2 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA KR PF08659.5 AFZ80495.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 KR domain RNA_pol_A_bac PF01000.21 AFZ80496.1 - 1.2e-10 41.5 0.0 6.7e-10 39.1 0.0 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AFZ80496.1 - 0.0055 15.8 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_CTD PF03118.10 AFZ80496.1 - 0.048 13.0 0.8 1 8.8 0.1 2.5 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Wyosine_form PF08608.7 AFZ80497.1 - 1e-25 89.6 0.1 2e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 AFZ80497.1 - 1.3e-23 83.9 0.1 3e-23 82.7 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily FAM219A PF15260.1 AFZ80497.1 - 0.058 13.7 1.5 0.13 12.6 1.0 1.5 1 0 0 1 1 1 0 Protein family FAM219A Orthopox_F7 PF05813.7 AFZ80498.1 - 0.11 12.3 2.0 0.53 10.2 0.1 3.0 4 0 0 4 4 4 0 Orthopoxvirus F7 protein AAA_23 PF13476.1 AFZ80499.1 - 6.5e-17 62.5 0.4 6.5e-17 62.5 0.3 5.3 2 2 1 3 3 3 1 AAA domain SMC_N PF02463.14 AFZ80499.1 - 2.2e-12 46.6 40.6 1.4e-11 44.0 28.1 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Reo_sigmaC PF04582.7 AFZ80499.1 - 0.0034 16.6 0.9 0.0034 16.6 0.6 5.1 3 2 1 5 5 5 2 Reovirus sigma C capsid protein IncA PF04156.9 AFZ80499.1 - 0.0049 16.4 72.8 0.038 13.6 0.4 6.2 4 2 1 5 5 5 3 IncA protein SbcCD_C PF13558.1 AFZ80499.1 - 0.018 14.9 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 AFZ80499.1 - 0.026 14.0 0.0 0.061 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FATC PF02260.15 AFZ80499.1 - 0.2 11.1 0.2 0.57 9.6 0.2 1.8 1 0 0 1 1 1 0 FATC domain Filament PF00038.16 AFZ80499.1 - 1.1 8.6 70.6 4.2 6.7 17.0 5.7 3 2 0 3 3 3 0 Intermediate filament protein DUF869 PF05911.6 AFZ80499.1 - 1.8 6.7 67.6 1.4 7.0 19.0 3.3 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) AMP-binding PF00501.23 AFZ80500.1 - 2e-67 227.4 0.0 2.5e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AFZ80500.1 - 0.003 18.4 0.0 0.0066 17.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glycos_transf_4 PF00953.16 AFZ80501.1 - 2.4e-33 115.2 17.0 2.4e-33 115.2 11.8 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF962 PF06127.6 AFZ80501.1 - 0.34 10.8 4.5 0.36 10.7 1.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF962) LPAM_1 PF08139.7 AFZ80501.1 - 0.39 11.0 3.5 16 5.8 0.2 3.3 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Lactamase_B_2 PF12706.2 AFZ80502.1 - 1.7e-21 76.6 0.4 1.2e-17 64.1 0.1 2.6 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AFZ80502.1 - 2.3e-07 30.6 0.7 4e-07 29.8 0.5 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily TAP42 PF04177.7 AFZ80503.1 - 8.5e-37 126.8 6.3 2.4e-36 125.4 4.4 1.6 1 1 0 1 1 1 1 TAP42-like family Rotamase PF00639.16 AFZ80505.1 - 3.9e-22 78.7 0.0 5.1e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 AFZ80505.1 - 1.3e-18 67.3 0.0 1.5e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 AFZ80505.1 - 4.2e-06 27.3 0.0 4.9e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Methyltransf_5 PF01795.14 AFZ80506.1 - 1.2e-85 287.5 0.2 8e-85 284.8 0.2 1.9 1 1 0 1 1 1 1 MraW methylase family Methyltransf_26 PF13659.1 AFZ80506.1 - 5.8e-05 23.0 0.0 0.0024 17.8 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 AFZ80506.1 - 9.9e-05 21.7 0.0 0.16 11.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.1 AFZ80506.1 - 0.00015 21.4 0.0 0.38 10.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 AFZ80506.1 - 0.00089 19.8 0.0 0.17 12.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 AFZ80506.1 - 0.033 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.7 AFZ80506.1 - 0.059 13.8 0.0 0.42 11.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 AFZ80506.1 - 0.084 13.3 0.0 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PB1-F2 PF11986.3 AFZ80508.1 - 0.065 13.2 0.9 2 8.5 0.0 2.6 2 0 0 2 2 2 0 Influenza A Proapoptotic protein RRM_1 PF00076.17 AFZ80509.1 - 6.2e-07 28.9 0.0 0.0007 19.1 0.0 3.7 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ80509.1 - 0.001 18.8 0.0 0.022 14.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.8 AFZ80509.1 - 0.0021 18.5 0.0 0.0048 17.3 0.0 1.6 1 0 0 1 1 1 1 SPOC domain RRM_6 PF14259.1 AFZ80509.1 - 0.016 15.1 0.1 10 6.2 0.0 3.4 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2604 PF10790.4 AFZ80509.1 - 0.017 15.2 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein of Unknown function (DUF2604) Met_asp_mut_E PF06368.6 AFZ80510.1 - 0.02 13.1 0.0 0.023 12.8 0.0 1.0 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Ribosomal_L22 PF00237.14 AFZ80511.1 - 1.5e-08 34.5 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e MgtE_N PF03448.12 AFZ80511.1 - 0.031 14.5 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain DUF2582 PF10771.4 AFZ80511.1 - 0.095 12.5 0.2 0.82 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2582) Kin17_mid PF10357.4 AFZ80512.1 - 1.1e-45 154.3 3.8 1.9e-45 153.5 1.9 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 AFZ80512.1 - 0.0057 16.8 3.3 0.018 15.2 2.3 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AFZ80512.1 - 0.014 15.5 5.1 0.043 13.9 3.6 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding KOW PF00467.24 AFZ80512.1 - 0.083 12.6 0.2 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 KOW motif DUF3593 PF12159.3 AFZ80512.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Toxin_64 PF15542.1 AFZ80513.1 - 0.35 11.4 2.5 0.78 10.3 0.1 2.5 2 0 0 2 2 2 0 Putative toxin 64 Synaptobrevin PF00957.16 AFZ80514.1 - 2.6e-05 23.7 0.1 2.8e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Synaptobrevin CtaG_Cox11 PF04442.9 AFZ80515.1 - 5.9e-49 165.7 0.1 8.1e-49 165.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 OB_NTP_bind PF07717.11 AFZ80516.1 - 7.5e-13 48.3 0.0 1.8e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 AFZ80516.1 - 6.3e-12 45.4 0.0 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Prefoldin PF02996.12 AFZ80517.1 - 4.6e-23 81.1 1.1 6.6e-23 80.6 0.8 1.3 1 0 0 1 1 1 1 Prefoldin subunit DUF4600 PF15372.1 AFZ80517.1 - 0.0094 16.1 2.0 0.08 13.1 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4600) SlyX PF04102.7 AFZ80517.1 - 0.069 13.5 4.0 0.81 10.1 1.0 2.3 2 0 0 2 2 2 0 SlyX IncA PF04156.9 AFZ80517.1 - 0.19 11.3 5.1 0.13 11.8 1.5 1.8 2 0 0 2 2 2 0 IncA protein Cep57_MT_bd PF06657.8 AFZ80517.1 - 0.2 11.6 5.2 6.1 6.8 0.8 2.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Glycolytic PF00274.14 AFZ80518.1 - 2.3e-161 535.9 0.0 2.6e-161 535.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I PRMT5 PF05185.11 AFZ80519.1 - 3e-134 448.3 0.0 3.6e-134 448.0 0.0 1.0 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 AFZ80519.1 - 0.002 17.7 0.0 0.007 15.9 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein V_cholerae_RfbT PF05575.6 AFZ80519.1 - 0.054 12.5 0.1 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Vibrio cholerae RfbT protein Sec23_trunk PF04811.10 AFZ80520.1 - 3e-44 151.2 0.0 6.3e-44 150.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 AFZ80520.1 - 2.5e-19 69.5 0.0 7.6e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 AFZ80520.1 - 2.4e-14 52.5 5.9 4.9e-14 51.6 4.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 AFZ80520.1 - 8.1e-11 41.2 0.0 3.4e-10 39.2 0.0 2.1 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 AFZ80520.1 - 1.3e-07 31.2 0.0 3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat VWA PF00092.23 AFZ80520.1 - 8.3e-07 28.8 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 AFZ80520.1 - 0.00012 22.2 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Use1 PF09753.4 AFZ80523.1 - 9.5e-07 28.5 7.8 1.6e-06 27.7 5.3 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF3753 PF12575.3 AFZ80523.1 - 0.098 12.4 4.4 0.061 13.1 0.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) LEDGF PF11467.3 AFZ80523.1 - 0.37 10.5 3.4 0.91 9.2 2.3 1.9 1 1 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) RNA_pol_Rpb1_5 PF04998.12 AFZ80523.1 - 0.41 9.8 2.6 0.6 9.3 1.8 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 K167R PF08065.7 AFZ80523.1 - 0.65 10.1 3.2 12 5.9 0.8 2.2 2 0 0 2 2 2 0 K167R (NUC007) repeat DUF912 PF06024.7 AFZ80523.1 - 3.4 7.7 6.3 14 5.7 4.4 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FAINT PF04385.10 AFZ80525.1 - 4.9e-13 48.7 5.9 0.003 17.3 0.0 5.2 4 0 0 4 4 4 4 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 AFZ80525.1 - 2.4e-12 47.2 0.0 4.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ80525.1 - 1.4e-11 44.3 0.0 4.5e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ80525.1 - 1.9e-08 34.0 0.1 1e-07 31.7 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase LCAT PF02450.10 AFZ80525.1 - 0.005 15.8 0.5 0.045 12.7 0.0 2.3 2 1 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 AFZ80525.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 AFZ80525.1 - 0.011 15.3 0.0 0.73 9.3 0.0 2.8 3 0 0 3 3 3 0 alpha/beta hydrolase fold PGAP1 PF07819.8 AFZ80525.1 - 0.031 13.8 0.0 0.07 12.6 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Hydrolase_3 PF08282.7 AFZ80526.1 - 6.2e-38 130.8 0.0 8.6e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AFZ80526.1 - 4.2e-05 23.7 0.2 0.0069 16.5 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AFZ80526.1 - 0.0018 17.6 0.0 0.028 13.7 0.0 2.2 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Fe-S_assembly PF04384.8 AFZ80527.1 - 1.3e-18 67.0 0.1 1.9e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster assembly SRP9-21 PF05486.7 AFZ80527.1 - 0.0037 16.9 0.1 0.019 14.6 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) Ter PF05472.6 AFZ80527.1 - 0.087 11.9 0.0 0.25 10.4 0.0 1.6 1 1 1 2 2 2 0 DNA replication terminus site-binding protein (Ter protein) COX2 PF00116.15 AFZ80528.1 - 0.085 12.6 0.2 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, periplasmic domain Arm PF00514.18 AFZ80529.1 - 2.8 7.8 21.3 5.6 6.9 0.0 8.8 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat PNK3P PF08645.6 AFZ80530.1 - 1e-45 155.0 0.0 1.7e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 AFZ80530.1 - 1.1e-09 38.3 0.0 2.2e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 AFZ80530.1 - 7.7e-05 22.0 0.0 0.36 10.0 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 AFZ80530.1 - 0.001 18.2 0.0 0.47 9.5 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin AAA_17 PF13207.1 AFZ80530.1 - 0.0041 17.9 0.0 0.031 15.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AFZ80530.1 - 0.028 14.5 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AFZ80530.1 - 0.035 14.0 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Hydrolase_like PF13242.1 AFZ80530.1 - 0.044 13.5 0.0 0.4 10.4 0.0 2.4 2 0 0 2 2 2 0 HAD-hyrolase-like AAA_25 PF13481.1 AFZ80530.1 - 0.047 13.0 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AFZ80530.1 - 0.12 12.1 0.1 0.85 9.4 0.0 2.4 2 1 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 AFZ80530.1 - 0.19 11.6 0.0 0.51 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain COG5 PF10392.4 AFZ80531.1 - 0.0067 16.3 6.0 0.011 15.7 0.8 3.1 3 0 0 3 3 3 1 Golgi transport complex subunit 5 TPR_12 PF13424.1 AFZ80532.1 - 1.2e-07 31.5 5.5 0.034 14.0 0.0 5.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 AFZ80532.1 - 1e-06 28.8 7.3 3.5 8.5 0.0 7.4 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ80532.1 - 2e-05 24.0 10.1 0.18 11.6 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 AFZ80532.1 - 8.2e-05 22.2 15.3 0.22 11.5 0.0 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat RPN7 PF10602.4 AFZ80532.1 - 0.00013 21.3 0.2 0.0025 17.2 0.0 2.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_16 PF13432.1 AFZ80532.1 - 0.00018 22.1 0.5 10 6.9 0.0 5.5 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 AFZ80532.1 - 0.069 12.8 15.8 0.45 10.2 0.2 6.8 7 2 2 9 9 9 0 TPR repeat TPR_7 PF13176.1 AFZ80532.1 - 0.082 12.7 4.8 11 6.0 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat HAT PF02184.11 AFZ80532.1 - 0.89 9.3 14.7 8.4 6.2 0.9 5.6 5 0 0 5 5 5 0 HAT (Half-A-TPR) repeat TPR_1 PF00515.23 AFZ80532.1 - 5.7 6.7 12.7 14 5.4 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat RRM_1 PF00076.17 AFZ80533.1 - 9.4e-16 57.2 0.0 7.9e-11 41.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ80533.1 - 3.6e-12 46.0 0.0 1.5e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 AFZ80533.1 - 4.5e-09 35.9 5.3 9e-09 35.0 3.7 1.5 1 0 0 1 1 1 1 WW domain RRM_5 PF13893.1 AFZ80533.1 - 1.3e-06 28.1 0.0 5e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V-SNARE_C PF12352.3 AFZ80534.1 - 1.5e-06 28.1 2.1 8.1e-06 25.8 0.1 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 AFZ80534.1 - 0.0012 18.4 2.7 0.0018 17.8 0.2 2.2 2 1 0 2 2 2 1 Sec20 V-SNARE PF05008.10 AFZ80534.1 - 0.0032 17.5 7.3 0.0086 16.2 0.2 3.0 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus NRDE PF05742.7 AFZ80534.1 - 0.01 15.1 0.1 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 NRDE protein SNARE PF05739.14 AFZ80534.1 - 0.018 14.6 0.4 0.018 14.6 0.3 2.6 3 0 0 3 3 3 0 SNARE domain Pex24p PF06398.6 AFZ80534.1 - 0.031 13.0 0.5 0.046 12.5 0.2 1.4 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF4144 PF13642.1 AFZ80534.1 - 0.11 12.8 0.6 0.31 11.3 0.1 1.9 2 0 0 2 2 2 0 protein structure with unknown function B56 PF01603.15 AFZ80535.1 - 1.4e-128 429.0 17.0 1.8e-128 428.6 11.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) TP53IP5 PF15331.1 AFZ80536.1 - 0.42 10.4 4.4 0.66 9.8 3.1 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF3940 PF13076.1 AFZ80537.1 - 0.097 12.2 0.0 0.48 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3940) GET2 PF08690.5 AFZ80537.1 - 0.12 11.5 7.5 0.13 11.4 5.2 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Siah-Interact_N PF09032.6 AFZ80537.1 - 0.26 11.3 11.0 0.43 10.6 3.7 2.6 2 1 0 2 2 2 0 Siah interacting protein, N terminal DUF3091 PF11291.3 AFZ80537.1 - 0.29 11.1 4.4 0.26 11.2 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3091) Chal_sti_synt_N PF00195.14 AFZ80538.1 - 0.0077 15.5 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain HECT PF00632.20 AFZ80540.1 - 1.9e-66 224.4 0.6 5.6e-66 222.8 0.4 1.8 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Nol1_Nop2_Fmu PF01189.12 AFZ80541.1 - 8e-25 87.7 0.0 7e-24 84.6 0.0 2.4 1 1 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 AFZ80541.1 - 0.0019 17.8 0.1 0.0062 16.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain VitD-bind_III PF09164.5 AFZ80541.1 - 0.011 15.3 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 Vitamin D binding protein, domain III FtsJ PF01728.14 AFZ80541.1 - 0.02 14.8 0.0 0.14 12.1 0.0 2.2 1 1 1 2 2 2 0 FtsJ-like methyltransferase SAM_2 PF07647.12 AFZ80542.1 - 0.00065 19.4 0.0 0.097 12.5 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 AFZ80542.1 - 0.0059 16.7 0.0 0.18 12.0 0.0 2.8 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) Pribosyltran PF00156.22 AFZ80544.1 - 1.6e-16 60.1 0.2 2.2e-16 59.6 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain S-AdoMet_synt_N PF00438.15 AFZ80544.1 - 0.091 12.9 0.0 0.41 10.9 0.0 2.2 3 0 0 3 3 3 0 S-adenosylmethionine synthetase, N-terminal domain HEAT PF02985.17 AFZ80545.1 - 5.2e-10 38.5 0.7 0.0015 18.3 0.0 6.5 5 0 0 5 5 5 2 HEAT repeat IBN_N PF03810.14 AFZ80545.1 - 8e-09 35.2 1.0 6.8e-08 32.3 0.2 3.1 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 AFZ80545.1 - 1e-07 32.1 0.9 5e-06 26.8 0.0 4.2 6 0 0 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.1 AFZ80545.1 - 3.1e-06 27.3 0.1 0.0096 16.1 0.0 4.5 4 1 1 5 5 5 1 HEAT repeats Cnd1 PF12717.2 AFZ80545.1 - 0.0074 16.1 7.5 0.1 12.4 0.0 4.4 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF1981 PF09324.5 AFZ80545.1 - 0.021 14.3 0.5 5.3 6.6 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) Arm PF00514.18 AFZ80545.1 - 0.027 14.2 1.3 0.4 10.5 0.0 3.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat JmjC PF02373.17 AFZ80547.1 - 1.9e-37 127.9 0.2 4.2e-37 126.8 0.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.11 AFZ80547.1 - 8.8e-07 28.8 9.7 3e-06 27.2 6.7 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger JmjN PF02375.12 AFZ80547.1 - 4.9e-06 25.9 0.2 1.1e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 jmjN domain EMA PF02488.10 AFZ80548.1 - 2e-36 125.7 1.7 2.2e-36 125.6 1.2 1.0 1 0 0 1 1 1 1 Merozoite Antigen YSIRK_signal PF04650.12 AFZ80548.1 - 0.54 9.8 3.5 0.89 9.1 2.4 1.4 1 0 0 1 1 1 0 YSIRK type signal peptide Brix PF04427.13 AFZ80549.1 - 2.8e-48 164.1 0.4 3.7e-48 163.7 0.3 1.1 1 0 0 1 1 1 1 Brix domain Exo5 PF09810.4 AFZ80550.1 - 4.4e-81 272.5 14.5 2.7e-79 266.7 10.1 2.0 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 AFZ80550.1 - 9.2e-07 28.4 2.3 1.7e-06 27.6 1.6 1.5 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily RNase_HII PF01351.13 AFZ80551.1 - 3.1e-46 157.5 0.0 4.5e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII AKAP7_NLS PF10469.4 AFZ80552.1 - 4.1e-07 29.9 0.4 2.3e-06 27.4 0.3 2.1 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Corona_NS2A PF05213.7 AFZ80552.1 - 0.0032 16.8 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 Coronavirus NS2A protein LigT_PEase PF02834.11 AFZ80552.1 - 0.048 13.6 0.0 0.74 9.8 0.0 2.6 2 0 0 2 2 2 0 LigT like Phosphoesterase DUF3883 PF13020.1 AFZ80553.1 - 2.3e-19 68.9 1.1 5.2e-19 67.7 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) Hexokinase_1 PF00349.16 AFZ80554.1 - 9.3e-58 194.9 0.0 1.3e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 AFZ80554.1 - 3.8e-50 170.3 0.0 5.7e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF2103 PF09876.4 AFZ80554.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2103) Kelch_4 PF13418.1 AFZ80558.1 - 2.9e-46 155.0 21.2 2.2e-10 40.1 0.1 6.6 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.1 AFZ80558.1 - 3.4e-35 119.3 10.2 3e-06 27.2 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 AFZ80558.1 - 2.3e-26 91.2 9.8 5.8e-06 26.1 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 AFZ80558.1 - 1.3e-21 75.7 18.2 0.00056 19.9 0.1 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_1 PF01344.20 AFZ80558.1 - 5.6e-21 73.8 9.4 0.00027 20.4 0.0 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.10 AFZ80558.1 - 8e-15 53.9 12.7 0.00016 21.2 0.2 6.3 6 1 0 6 6 6 3 Kelch motif EB PF01683.13 AFZ80558.1 - 0.17 12.0 5.5 0.6 10.2 3.8 2.0 1 1 0 1 1 1 0 EB module hEGF PF12661.2 AFZ80558.1 - 0.24 11.5 3.5 0.71 10.0 2.4 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.8 AFZ80558.1 - 1.5 9.0 21.0 0.039 14.1 9.6 2.2 2 0 0 2 2 2 0 EGF-like domain Sin_N PF04801.8 AFZ80559.1 - 3.3e-18 65.7 7.2 2.2e-12 46.5 0.0 4.3 3 2 0 3 3 3 3 Sin-like protein conserved region DUF1160 PF06648.6 AFZ80559.1 - 0.05 13.3 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) ATG16 PF08614.6 AFZ80560.1 - 5.7e-05 23.0 16.7 5.7e-05 23.0 11.6 2.2 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) ERM PF00769.14 AFZ80560.1 - 0.0048 16.4 16.9 0.0091 15.5 11.7 1.5 1 1 0 1 1 1 1 Ezrin/radixin/moesin family Val_tRNA-synt_C PF10458.4 AFZ80560.1 - 0.027 14.5 0.6 0.027 14.5 0.4 2.5 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm LRR_3 PF07725.7 AFZ80560.1 - 0.11 12.3 0.2 0.43 10.4 0.1 2.1 1 0 0 1 1 1 0 Leucine Rich Repeat Cep57_CLD_2 PF14197.1 AFZ80560.1 - 0.25 11.3 13.9 2.4 8.1 2.7 3.5 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Tropomyosin_1 PF12718.2 AFZ80560.1 - 7.8 6.3 26.6 0.29 10.9 7.6 3.0 2 1 1 3 3 3 0 Tropomyosin like DUF3450 PF11932.3 AFZ80560.1 - 8.4 5.5 16.8 1.8 7.7 6.4 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) DUF4446 PF14584.1 AFZ80560.1 - 9.7 6.0 9.7 1.1 9.0 2.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) zf-C2H2_4 PF13894.1 AFZ80561.1 - 0.0041 17.3 0.3 0.0041 17.3 0.2 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AFZ80561.1 - 0.047 14.0 0.6 0.047 14.0 0.4 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.2 AFZ80561.1 - 2.6 8.3 4.4 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type OPA3 PF07047.7 AFZ80562.1 - 9e-40 135.5 0.0 1.1e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) KH_dom-like PF14714.1 AFZ80562.1 - 0.14 12.1 0.2 9.3 6.3 0.0 2.5 2 1 1 3 3 3 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal MMR_HSR1 PF01926.18 AFZ80563.1 - 1.4e-09 37.9 0.9 1.3e-08 34.7 0.1 2.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AFZ80563.1 - 9.1e-05 21.9 0.2 0.057 12.8 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 AFZ80563.1 - 0.00016 20.9 0.0 0.00028 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 AFZ80563.1 - 0.00052 19.3 1.4 0.074 12.3 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_16 PF13191.1 AFZ80563.1 - 0.00084 19.3 0.0 0.0048 16.9 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 AFZ80563.1 - 0.0036 17.7 0.2 0.49 10.8 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 AFZ80563.1 - 0.012 15.4 0.8 0.34 10.6 0.1 2.4 1 1 1 2 2 2 0 Dynamin family DEAD PF00270.24 AFZ80564.1 - 2.1e-29 102.2 0.1 3.9e-29 101.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ80564.1 - 5.6e-21 74.1 0.0 1.3e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ80564.1 - 0.007 16.2 0.0 0.026 14.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF846 PF05832.7 AFZ80566.1 - 8.8e-22 77.3 15.7 1.1e-21 77.0 10.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Peptidase_A24 PF01478.13 AFZ80566.1 - 0.84 9.8 8.9 5.4 7.2 0.3 2.2 2 0 0 2 2 2 0 Type IV leader peptidase family TPR_19 PF14559.1 AFZ80568.1 - 9.5e-22 77.1 1.2 0.024 14.9 0.0 9.6 10 1 0 10 10 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 AFZ80568.1 - 2.7e-20 70.5 0.4 0.054 13.4 0.0 10.6 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 AFZ80568.1 - 2.2e-17 62.4 4.2 0.0017 17.9 0.0 9.2 6 2 3 10 10 10 6 TPR repeat TPR_16 PF13432.1 AFZ80568.1 - 1.1e-14 54.6 1.9 0.00099 19.7 0.0 9.0 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 AFZ80568.1 - 1.8e-14 52.8 6.2 0.93 10.3 0.0 9.4 8 1 2 10 10 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 AFZ80568.1 - 2.6e-12 46.4 5.7 0.058 13.3 0.0 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 AFZ80568.1 - 3.8e-09 36.3 4.4 0.01 16.2 0.1 8.5 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 AFZ80568.1 - 1e-08 34.3 6.3 1.1 8.9 0.0 9.6 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ80568.1 - 1.9e-07 30.3 7.2 2.6 8.0 0.0 7.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 AFZ80568.1 - 5.4e-06 26.1 3.6 16 5.9 0.0 8.4 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_4 PF07721.9 AFZ80568.1 - 0.00038 20.5 0.0 23 5.8 0.0 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat YfiO PF13525.1 AFZ80568.1 - 0.0078 15.7 1.8 0.52 9.7 0.1 3.8 3 1 0 3 3 3 1 Outer membrane lipoprotein Apc3 PF12895.2 AFZ80568.1 - 0.037 14.1 18.0 1.3 9.2 0.0 7.0 7 1 0 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 RAP PF08373.5 AFZ80569.1 - 0.036 13.8 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 RAP domain NifU PF01106.12 AFZ80570.1 - 3.4e-16 58.7 0.0 4.8e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 NifU-like domain YjfB_motility PF14070.1 AFZ80571.1 - 0.09 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative motility protein PP2C PF00481.16 AFZ80572.1 - 4.5e-41 140.9 0.0 5.6e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 AFZ80572.1 - 0.0083 15.5 0.0 0.014 14.8 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C ABC1 PF03109.11 AFZ80573.1 - 8.2e-26 90.3 0.0 1.6e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 AFZ80573.1 - 0.001 18.8 0.0 0.67 9.6 0.0 3.1 3 0 0 3 3 3 2 Phosphotransferase enzyme family Ribosomal_L33 PF00471.15 AFZ80574.1 - 6.8e-19 67.8 4.6 1.1e-18 67.2 3.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L33 ACBP PF00887.14 AFZ80575.1 - 5.7e-30 102.8 2.3 6.1e-30 102.7 1.6 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Corona_NS2 PF04753.7 AFZ80575.1 - 0.033 14.1 0.1 0.036 14.0 0.1 1.1 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 AP2 PF00847.15 AFZ80576.1 - 6.1e-10 39.0 2.2 6.1e-10 39.0 1.5 2.6 3 0 0 3 3 3 1 AP2 domain EMA PF02488.10 AFZ80577.1 - 2.9e-106 354.5 11.0 3.3e-106 354.3 7.6 1.0 1 0 0 1 1 1 1 Merozoite Antigen FluMu_gp41 PF10109.4 AFZ80578.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Mu-like prophage FluMu protein gp41 NPV_P10 PF05531.7 AFZ80579.1 - 0.071 13.3 0.7 0.16 12.2 0.5 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PAP_central PF04928.12 AFZ80581.1 - 5.8e-99 330.0 0.1 8e-99 329.5 0.1 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 AFZ80581.1 - 6.4e-35 120.0 0.1 1.1e-34 119.2 0.1 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 AFZ80581.1 - 3.6e-05 24.0 0.0 8.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.1 AFZ80581.1 - 0.11 12.4 0.3 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) ORC2 PF04084.9 AFZ80582.1 - 2.4e-46 158.1 5.3 3.9e-46 157.3 3.6 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DUF835 PF05763.7 AFZ80582.1 - 0.0047 16.4 0.1 0.013 15.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF835) NACHT PF05729.7 AFZ80582.1 - 0.07 12.7 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Prp19_bind PF06991.6 AFZ80582.1 - 1.3 8.2 8.4 0.28 10.4 2.2 2.1 1 1 1 2 2 2 0 Splicing factor, Prp19-binding domain DnaJ PF00226.26 AFZ80583.1 - 2.4e-23 81.6 1.6 3.8e-23 80.9 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AFZ80583.1 - 6.8e-22 77.1 2.5 1.4e-17 63.2 0.1 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AFZ80583.1 - 0.25 11.4 6.5 0.52 10.3 4.5 1.5 1 0 0 1 1 1 0 DnaJ central domain RAP PF08373.5 AFZ80584.1 - 2.9e-14 52.5 1.7 1e-13 50.8 1.2 2.1 1 0 0 1 1 1 1 RAP domain GatB_N PF02934.10 AFZ80586.1 - 2.6e-62 210.2 0.5 4.4e-56 189.8 0.1 2.2 2 0 0 2 2 2 2 GatB/GatE catalytic domain GatB_Yqey PF02637.13 AFZ80586.1 - 1.6e-10 40.9 0.1 3.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 GatB domain 2OG-FeII_Oxy_2 PF13532.1 AFZ80588.1 - 0.044 13.6 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RNA_pol_A_bac PF01000.21 AFZ80589.1 - 2.5e-23 82.3 0.0 6.8e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AFZ80589.1 - 1.3e-17 62.6 0.0 1.7e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.1 AFZ80589.1 - 0.013 14.9 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Dus PF01207.12 AFZ80590.1 - 7.4e-54 182.6 0.0 1e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) CS PF04969.11 AFZ80594.1 - 7e-09 36.1 0.2 1.5e-08 35.0 0.2 1.6 1 0 0 1 1 1 1 CS domain DUF807 PF05660.6 AFZ80594.1 - 0.00028 20.5 0.1 0.00045 19.8 0.1 1.3 1 0 0 1 1 1 1 Coxiella burnetii protein of unknown function (DUF807) Aminotran_5 PF00266.14 AFZ80596.1 - 8e-88 294.6 0.0 9.6e-88 294.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 AFZ80596.1 - 8.9e-05 21.6 0.0 0.00018 20.7 0.0 1.4 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 AFZ80596.1 - 0.00024 19.6 0.0 0.0004 18.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 AFZ80596.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase WHIM2 PF15613.1 AFZ80599.1 - 0.022 14.7 2.1 0.022 14.6 0.2 2.0 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 2 Telomere_reg-2 PF10193.4 AFZ80601.1 - 0.021 15.0 1.2 0.04 14.1 0.8 1.5 1 0 0 1 1 1 0 Telomere length regulation protein Methyltransf_31 PF13847.1 AFZ80601.1 - 1 8.9 3.9 3.3 7.2 0.5 2.4 1 1 1 2 2 2 0 Methyltransferase domain cwf18 PF08315.7 AFZ80602.1 - 9e-21 74.6 1.8 1.3e-20 74.1 1.2 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor PBC PF03792.8 AFZ80602.1 - 0.2 11.3 5.6 0.21 11.2 1.4 2.0 1 1 1 2 2 2 0 PBC domain PA14 PF07691.7 AFZ80603.1 - 7.2e-25 87.3 0.0 4.9e-24 84.6 0.0 2.4 2 0 0 2 2 2 1 PA14 domain BNR PF02012.15 AFZ80604.1 - 1.9e-06 26.8 14.4 0.67 10.0 0.1 8.5 8 0 0 8 8 8 3 BNR/Asp-box repeat DUF4056 PF13265.1 AFZ80604.1 - 0.052 12.5 0.0 0.099 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) DUF663 PF04950.7 AFZ80605.1 - 8.8e-79 264.5 0.0 1.2e-78 264.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 AFZ80605.1 - 1e-19 69.8 0.0 1.9e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain CLAG PF03805.8 AFZ80606.1 - 2.3e-23 81.6 11.4 6.6e-13 47.0 6.3 2.4 3 0 0 3 3 3 2 Cytoadherence-linked asexual protein tRNA-synt_1g PF09334.6 AFZ80607.1 - 1.6e-103 346.4 0.0 1.1e-102 343.6 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AFZ80607.1 - 2.5e-33 114.9 0.6 3.3e-18 65.0 0.0 3.4 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 AFZ80607.1 - 1.5e-14 53.8 0.0 2.8e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 AFZ80607.1 - 2.1e-05 23.4 0.0 0.00056 18.6 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1d PF00750.14 AFZ80607.1 - 0.0023 16.7 0.0 0.18 10.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (R) Cyt-b5 PF00173.23 AFZ80609.1 - 9.6e-16 57.3 0.0 1.2e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Atracotoxin PF05353.6 AFZ80611.1 - 9.6 6.1 9.7 0.15 11.9 1.3 2.0 2 0 0 2 2 2 0 Delta Atracotoxin DUF2583 PF10762.4 AFZ80612.1 - 5.8 7.1 7.0 5.9 7.0 0.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2583) Atracotoxin PF05353.6 AFZ80612.1 - 9.3 6.1 9.8 0.15 11.9 1.3 2.1 2 0 0 2 2 2 0 Delta Atracotoxin adh_short PF00106.20 AFZ80616.1 - 3.8e-19 69.2 0.0 2.3e-18 66.6 0.0 1.9 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 AFZ80616.1 - 3.1e-06 27.1 0.1 4.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AFZ80616.1 - 1.4e-05 24.8 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AFZ80616.1 - 0.00031 20.2 0.0 0.00043 19.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 AFZ80616.1 - 0.042 13.9 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 AFZ80616.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding FAINT PF04385.10 AFZ80618.1 - 4.3e-73 241.1 33.9 7.9e-08 32.0 0.2 14.8 14 0 0 14 14 14 14 Domain of unknown function, DUF529 Tox-SHH PF15652.1 AFZ80618.1 - 0.0055 17.2 0.7 8 7.1 0.0 3.9 3 0 0 3 3 3 2 HNH/Endo VII superfamily toxin with a SHH signature Pox_Ag35 PF03286.9 AFZ80619.1 - 0.012 15.1 10.2 0.024 14.1 7.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Prp18 PF02840.10 AFZ80619.1 - 0.088 12.6 2.1 0.17 11.6 1.5 1.5 1 0 0 1 1 1 0 Prp18 domain Daxx PF03344.10 AFZ80619.1 - 0.15 10.4 16.2 0.21 10.0 11.2 1.1 1 0 0 1 1 1 0 Daxx Family FPL PF09758.4 AFZ80619.1 - 0.22 11.2 1.8 0.4 10.4 1.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein CDC45 PF02724.9 AFZ80619.1 - 1.8 6.5 12.2 2.3 6.1 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 AFZ80619.1 - 2.2 7.5 15.8 3.3 7.0 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 AFZ80619.1 - 3.2 6.6 9.0 5.5 5.8 6.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PA28_beta PF02252.13 AFZ80620.1 - 3.4e-63 211.6 2.0 3.4e-63 211.6 1.4 1.5 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit BAR_2 PF10455.4 AFZ80620.1 - 0.012 14.5 0.9 0.017 14.0 0.6 1.2 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Med28 PF11594.3 AFZ80620.1 - 0.061 13.5 3.0 0.31 11.3 0.1 2.4 1 1 1 2 2 2 0 Mediator complex subunit 28 PA28_alpha PF02251.13 AFZ80620.1 - 0.082 13.0 0.4 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit CTP_synth_N PF06418.9 AFZ80621.1 - 2.2e-116 387.7 0.2 3e-116 387.3 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 AFZ80621.1 - 7.2e-43 146.2 0.0 1.2e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AFZ80621.1 - 2.4e-05 23.9 0.1 0.00012 21.5 0.0 2.0 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 AFZ80621.1 - 0.0089 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1347 PF07079.6 AFZ80621.1 - 0.015 13.5 0.0 0.022 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) DNA_primase_S PF01896.14 AFZ80622.1 - 1.4e-46 157.9 0.3 2.2e-46 157.2 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit SSB PF00436.20 AFZ80623.1 - 5.2e-10 39.1 0.1 8.1e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 Single-strand binding protein family Trp_halogenase PF04820.9 AFZ80623.1 - 0.036 12.6 0.0 0.049 12.2 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Arf PF00025.16 AFZ80625.1 - 1e-14 54.1 0.0 7.3e-14 51.3 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AFZ80625.1 - 4.3e-07 29.5 0.0 2.4e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AFZ80625.1 - 1.9e-06 27.1 0.1 4.8e-06 25.9 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 AFZ80625.1 - 6.4e-05 22.2 0.3 0.00014 21.0 0.2 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AFZ80625.1 - 0.0001 22.2 0.0 0.00022 21.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AFZ80625.1 - 0.0008 19.9 0.0 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arch_ATPase PF01637.13 AFZ80625.1 - 0.0031 17.2 0.0 0.0082 15.8 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 AFZ80625.1 - 0.0032 17.3 0.3 0.015 15.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain Ras PF00071.17 AFZ80625.1 - 0.0036 16.7 0.1 0.017 14.5 0.0 1.9 1 1 0 1 1 1 1 Ras family AAA_35 PF14516.1 AFZ80625.1 - 0.028 13.0 0.0 0.048 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain T2SE PF00437.15 AFZ80625.1 - 0.039 12.8 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Pkinase PF00069.20 AFZ80627.1 - 1.9e-32 112.4 0.0 4.9e-31 107.8 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ80627.1 - 4.2e-17 62.0 0.0 5.8e-17 61.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AFZ80627.1 - 8.2e-07 28.2 0.0 1.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AFZ80627.1 - 0.0052 16.5 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AFZ80627.1 - 0.0081 15.0 0.4 0.016 14.0 0.3 1.5 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 AFZ80627.1 - 0.058 12.3 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Myb_DNA-binding PF00249.26 AFZ80628.1 - 2.2e-15 56.4 4.9 3.4e-08 33.4 0.6 3.4 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AFZ80628.1 - 5.8e-14 51.9 8.3 1.2e-09 38.0 0.6 3.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 AFZ80628.1 - 0.00011 22.2 3.6 0.003 17.6 0.3 3.4 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain FAINT PF04385.10 AFZ80629.1 - 4e-20 71.4 15.5 2.7e-05 23.8 0.0 5.6 5 1 0 5 5 5 4 Domain of unknown function, DUF529 Saf-Nte_pilin PF09460.5 AFZ80629.1 - 0.24 11.1 1.0 19 5.0 0.0 2.6 3 0 0 3 3 3 0 Saf-pilin pilus formation protein GCD14 PF08704.5 AFZ80630.1 - 3.3e-61 206.9 0.2 1.3e-60 204.9 0.0 1.8 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 AFZ80630.1 - 2.9e-08 33.4 0.0 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 AFZ80630.1 - 2.6e-07 29.8 0.0 4.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 AFZ80630.1 - 0.00034 21.3 0.0 0.00066 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AFZ80630.1 - 0.00043 20.8 0.0 0.00097 19.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AFZ80630.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 AFZ80630.1 - 0.034 13.6 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RRM_5 PF13893.1 AFZ80630.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDP-OH_P_transf PF01066.16 AFZ80631.1 - 4.8e-15 55.6 4.3 1e-14 54.6 3.0 1.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase SNAP PF14938.1 AFZ80632.1 - 3.6e-72 242.8 4.5 4.2e-72 242.6 3.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 AFZ80632.1 - 2.3e-06 27.4 3.5 0.026 14.4 0.5 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 AFZ80632.1 - 7.9e-05 22.9 1.0 0.38 11.5 0.2 3.6 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 AFZ80632.1 - 8.6e-05 22.1 11.6 0.0021 17.6 1.2 3.4 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 AFZ80632.1 - 0.0012 18.5 11.8 0.0055 16.5 0.9 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 AFZ80632.1 - 0.0048 16.5 6.6 0.37 10.7 0.0 4.4 4 2 1 5 5 4 1 Tetratricopeptide repeat DUF2225 PF09986.4 AFZ80632.1 - 0.01 15.3 0.7 0.62 9.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_1 PF00515.23 AFZ80632.1 - 0.019 14.5 12.6 0.11 12.1 1.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.4 AFZ80632.1 - 0.02 14.3 1.9 3.1 7.1 0.0 2.4 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_6 PF13174.1 AFZ80632.1 - 0.68 10.5 4.0 97 3.7 0.1 4.2 4 2 1 5 5 4 0 Tetratricopeptide repeat MIT PF04212.13 AFZ80632.1 - 0.95 9.3 7.2 1.1 9.2 0.1 3.4 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain NSF PF02071.15 AFZ80632.1 - 1.2 9.9 19.2 5 8.1 0.3 6.2 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_8 PF13181.1 AFZ80632.1 - 1.6 8.6 9.4 7.7 6.5 0.2 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 AFZ80632.1 - 7.5 7.3 6.0 5.2 7.8 0.5 3.1 2 2 1 3 3 3 0 Sel1 repeat WW PF00397.21 AFZ80633.1 - 1.1e-17 63.4 22.4 2.2e-10 40.1 2.6 3.7 3 0 0 3 3 3 2 WW domain FF PF01846.14 AFZ80633.1 - 1.5e-10 40.8 14.2 2.3e-05 24.2 0.3 4.7 5 0 0 5 5 5 2 FF domain FAINT PF04385.10 AFZ80633.1 - 0.0005 19.8 0.0 0.0027 17.5 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function, DUF529 FAM176 PF14851.1 AFZ80633.1 - 0.029 14.0 0.6 0.072 12.7 0.1 1.9 2 0 0 2 2 2 0 FAM176 family CTP_transf_2 PF01467.21 AFZ80634.1 - 2.1e-33 115.6 0.3 3.6e-18 66.1 0.1 2.3 2 0 0 2 2 2 2 Cytidylyltransferase HTH_16 PF12645.2 AFZ80634.1 - 0.032 14.1 0.1 3.4 7.6 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain FAD_syn PF06574.7 AFZ80634.1 - 0.063 12.8 0.1 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 FAD synthetase FAINT PF04385.10 AFZ80635.1 - 4.8e-13 48.7 0.8 2e-09 37.1 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Bt_P21 PF05560.6 AFZ80635.1 - 0.077 12.3 0.2 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Bacillus thuringiensis P21 molecular chaperone protein Sec20 PF03908.8 AFZ80637.1 - 5.7e-06 25.9 1.8 1.6e-05 24.4 1.2 1.8 1 0 0 1 1 1 1 Sec20 DUF2491 PF10679.4 AFZ80637.1 - 0.065 12.2 1.4 0.099 11.6 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) TfoX_C PF04994.8 AFZ80637.1 - 0.11 12.4 0.4 0.28 11.0 0.1 1.8 2 0 0 2 2 2 0 TfoX C-terminal domain Collagen PF01391.13 AFZ80639.1 - 0.023 14.2 22.1 0.052 13.0 15.3 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) IncA PF04156.9 AFZ80641.1 - 0.14 11.7 5.3 0.16 11.5 3.7 1.2 1 0 0 1 1 1 0 IncA protein Cauli_AT PF03233.8 AFZ80641.1 - 0.41 10.3 3.9 0.59 9.8 2.7 1.2 1 0 0 1 1 1 0 Aphid transmission protein YkuI_C PF10388.4 AFZ80641.1 - 0.89 9.2 6.4 2.7 7.6 2.5 2.2 2 0 0 2 2 2 0 EAL-domain associated signalling protein domain DUF740 PF05340.7 AFZ80641.1 - 5.3 5.2 8.2 6.2 5.0 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF272 PF03312.10 AFZ80642.1 - 0.0039 17.4 0.6 0.0064 16.7 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF272) EMA PF02488.10 AFZ80642.1 - 0.0075 15.7 0.5 0.0082 15.6 0.4 1.0 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 AFZ80643.1 - 4.3e-13 48.9 1.6 3.4e-09 36.4 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80643.1 - 0.0086 15.5 0.2 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Merozoite Antigen RP-C_C PF11800.3 AFZ80644.1 - 0.49 10.0 4.8 0.2 11.3 1.4 1.8 2 0 0 2 2 2 0 Replication protein C C-terminal region GP3 PF03076.9 AFZ80647.1 - 0.042 13.6 0.0 0.051 13.4 0.0 1.1 1 0 0 1 1 1 0 Equine arteritis virus GP3 FAINT PF04385.10 AFZ80649.1 - 4.2e-21 74.5 9.8 2.9e-09 36.6 0.9 3.7 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80649.1 - 5.5e-06 26.0 4.1 0.14 11.5 0.1 3.2 3 0 0 3 3 3 3 Merozoite Antigen STIL_N PF15253.1 AFZ80650.1 - 0.055 12.1 0.0 0.071 11.8 0.0 1.1 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus FAINT PF04385.10 AFZ80651.1 - 2.5e-16 59.2 8.5 0.0081 15.9 0.4 6.3 5 2 0 5 5 5 5 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80653.1 - 1.2e-12 47.5 0.0 7.4e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF4343 PF14243.1 AFZ80653.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) Peptidase_C1 PF00112.18 AFZ80654.1 - 3.5e-29 102.2 0.0 6.2e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Lectin_N PF03954.9 AFZ80654.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain zf-UBP PF02148.14 AFZ80655.1 - 2e-13 50.2 4.4 3.5e-13 49.4 3.1 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.24 AFZ80655.1 - 5.3e-08 32.2 0.0 1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HTH_WhiA PF02650.9 AFZ80655.1 - 0.069 13.5 0.0 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 WhiA C-terminal HTH domain DUF281 PF03436.8 AFZ80657.1 - 0.17 11.9 0.5 0.32 11.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF281) UCH PF00443.24 AFZ80658.1 - 1.3e-19 70.3 0.1 1.5e-19 70.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Viral_P18 PF04521.8 AFZ80659.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein FAINT PF04385.10 AFZ80659.1 - 0.11 12.3 0.3 0.19 11.6 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80661.1 - 1.5e-13 50.4 0.3 1.4e-05 24.8 0.1 3.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Hydrolase_3 PF08282.7 AFZ80663.1 - 3.9e-33 115.0 0.0 4.8e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AFZ80663.1 - 0.0003 20.1 0.0 0.032 13.5 0.0 2.5 3 0 0 3 3 3 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 AFZ80663.1 - 0.017 15.3 0.0 0.033 14.3 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Prenyltrans_1 PF13243.1 AFZ80663.1 - 0.14 12.1 0.0 0.58 10.1 0.0 1.8 2 0 0 2 2 2 0 Prenyltransferase-like RVT_1 PF00078.22 AFZ80664.1 - 1.1e-34 119.7 0.1 1.9e-34 118.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF368 PF04018.8 AFZ80665.1 - 0.098 11.8 0.3 9.5 5.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF368) Herpes_UL49_5 PF05702.6 AFZ80665.1 - 0.13 12.1 0.1 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein Reo_sigmaC PF04582.7 AFZ80665.1 - 5.3 6.1 14.9 2.8 7.0 0.1 4.5 4 1 1 5 5 5 0 Reovirus sigma C capsid protein MCM PF00493.18 AFZ80667.1 - 9.8e-124 412.4 0.0 1.5e-123 411.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AFZ80667.1 - 6.5e-11 42.7 0.0 2.1e-10 41.1 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 AFZ80667.1 - 1.4e-07 30.8 0.1 5.2e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AFZ80667.1 - 0.00021 21.0 0.0 0.00071 19.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AFZ80667.1 - 0.028 14.0 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FAINT PF04385.10 AFZ80668.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function, DUF529 Gin PF10764.4 AFZ80669.1 - 0.051 13.2 0.1 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin Apis_Csd PF11671.3 AFZ80670.1 - 0.075 12.8 2.1 0.087 12.6 1.4 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein FAINT PF04385.10 AFZ80672.1 - 0.0058 16.4 0.0 0.092 12.6 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function, DUF529 CBF PF03914.12 AFZ80673.1 - 1.1e-10 41.1 7.1 1.4e-10 40.9 1.3 2.9 2 1 1 3 3 3 2 CBF/Mak21 family FAINT PF04385.10 AFZ80674.1 - 2.6e-05 23.9 0.3 4.6e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 DUF4595 PF15283.1 AFZ80675.1 - 0.051 13.2 0.5 0.051 13.2 0.4 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4595) with porin-like fold ABC2_membrane_2 PF12679.2 AFZ80678.1 - 0.0035 16.2 9.2 0.36 9.6 4.1 2.1 2 0 0 2 2 2 2 ABC-2 family transporter protein Tetraspannin PF00335.15 AFZ80678.1 - 0.011 15.0 2.5 0.012 14.8 1.7 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF3808 PF10300.4 AFZ80678.1 - 0.018 13.6 0.1 0.022 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) YibE_F PF07907.6 AFZ80678.1 - 0.038 13.1 7.6 0.046 12.9 5.2 1.2 1 0 0 1 1 1 0 YibE/F-like protein 7TM_GPCR_Srd PF10317.4 AFZ80678.1 - 0.068 12.1 10.8 0.021 13.7 2.0 2.1 1 1 2 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srd DUF373 PF04123.8 AFZ80678.1 - 0.091 11.7 5.9 0.11 11.5 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF3816 PF12822.2 AFZ80678.1 - 0.74 9.6 14.0 12 5.7 7.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) SnoaL PF07366.7 AFZ80680.1 - 0.0011 18.5 0.4 0.065 12.8 0.1 2.5 1 1 1 2 2 2 1 SnoaL-like polyketide cyclase DUF3391 PF11871.3 AFZ80680.1 - 0.007 16.5 3.5 0.033 14.4 0.2 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3391) Baculo_PEP_C PF04513.7 AFZ80680.1 - 0.021 14.6 5.7 0.19 11.5 0.6 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3837 PF12939.2 AFZ80680.1 - 0.035 14.0 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) GspL_C PF12693.2 AFZ80680.1 - 0.038 13.7 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 GspL periplasmic domain PspB PF06667.7 AFZ80680.1 - 0.096 12.6 0.4 0.096 12.6 0.3 2.9 4 0 0 4 4 4 0 Phage shock protein B DUF2450 PF10475.4 AFZ80680.1 - 0.8 8.5 8.0 0.11 11.3 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) IncA PF04156.9 AFZ80680.1 - 2.6 7.5 10.6 8.8 5.8 0.6 3.3 3 0 0 3 3 3 0 IncA protein CHASE3 PF05227.8 AFZ80680.1 - 3.1 7.4 7.8 12 5.5 0.0 3.6 4 1 0 4 4 4 0 CHASE3 domain Laminin_II PF06009.7 AFZ80680.1 - 7 6.4 15.0 7.8 6.2 0.7 3.9 3 2 1 4 4 4 0 Laminin Domain II Ctr PF04145.10 AFZ80681.1 - 2.8e-10 40.4 17.3 2.6e-06 27.5 7.9 2.3 1 1 1 2 2 2 2 Ctr copper transporter family Ribosomal_S19 PF00203.16 AFZ80682.1 - 2.6e-30 103.8 0.0 3.9e-30 103.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Collagen PF01391.13 AFZ80683.1 - 0.0062 16.0 11.3 0.012 15.1 7.8 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF3840 PF12944.2 AFZ80683.1 - 0.09 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3840) HAUS6_N PF14661.1 AFZ80683.1 - 3.3 7.0 9.4 5.3 6.3 6.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FAINT PF04385.10 AFZ80684.1 - 9.1e-09 35.0 4.2 1e-05 25.2 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Fer2 PF00111.22 AFZ80687.1 - 1.1e-17 63.4 0.8 1.9e-17 62.7 0.5 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAINT PF04385.10 AFZ80688.1 - 2.4e-20 72.1 21.5 7.3e-07 28.9 1.6 5.7 5 0 0 5 5 5 5 Domain of unknown function, DUF529 TPR_11 PF13414.1 AFZ80689.1 - 3.7e-06 26.4 1.6 0.0015 18.1 0.2 2.2 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 AFZ80689.1 - 5.1e-06 26.0 1.4 7.7e-05 22.3 0.5 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 AFZ80689.1 - 1.1e-05 24.8 0.7 7.2e-05 22.2 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ80689.1 - 9.7e-05 21.8 1.3 0.021 14.5 0.1 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AFZ80689.1 - 0.0064 16.3 0.5 0.022 14.6 0.2 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.5 AFZ80689.1 - 0.022 13.5 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_17 PF13431.1 AFZ80689.1 - 0.051 13.7 0.1 0.41 10.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat YpjP PF14005.1 AFZ80689.1 - 0.079 12.7 1.5 2.2 8.0 0.7 2.2 2 0 0 2 2 2 0 YpjP-like protein CTP_transf_1 PF01148.15 AFZ80690.1 - 3.3e-54 184.2 33.8 1.4e-52 178.9 15.5 2.2 2 0 0 2 2 2 2 Cytidylyltransferase family Ribosomal_L16 PF00252.13 AFZ80692.1 - 1e-16 60.8 0.2 3.1e-16 59.3 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e EAP30 PF04157.11 AFZ80693.1 - 3.4e-38 131.0 0.1 3.8e-38 130.8 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family BACK PF07707.10 AFZ80693.1 - 0.018 14.8 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch Pox_D5 PF03288.11 AFZ80693.1 - 0.075 13.3 0.1 20 5.5 0.0 2.4 2 0 0 2 2 2 0 Poxvirus D5 protein-like FAINT PF04385.10 AFZ80694.1 - 2.7e-06 27.1 10.0 0.00022 20.9 1.3 3.3 3 1 0 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80695.1 - 1.2e-07 31.4 4.8 0.0013 18.5 0.4 2.9 2 0 0 2 2 2 2 Domain of unknown function, DUF529 PUA PF01472.15 AFZ80697.1 - 3.7e-16 58.6 0.0 5.3e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 PUA domain FlgM PF04316.8 AFZ80698.1 - 0.0019 18.0 1.6 0.0045 16.8 1.1 1.7 1 1 0 1 1 1 1 Anti-sigma-28 factor, FlgM DUF16 PF01519.11 AFZ80698.1 - 0.019 15.1 3.9 0.23 11.6 2.7 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF4259 PF14078.1 AFZ80698.1 - 0.14 12.6 3.5 0.19 12.2 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) DUF2310 PF10071.4 AFZ80698.1 - 0.15 11.0 0.8 0.3 10.0 0.5 1.7 1 1 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) ATG16 PF08614.6 AFZ80698.1 - 0.18 11.6 2.4 0.23 11.2 1.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Tic22 PF04278.7 AFZ80700.1 - 8.4e-11 41.6 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Tic22-like family DUF1110 PF06533.7 AFZ80700.1 - 0.16 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) Thioredoxin_2 PF13098.1 AFZ80701.1 - 0.3 11.2 1.4 0.43 10.7 1.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Peptidase_C1 PF00112.18 AFZ80702.1 - 3e-62 210.3 0.0 4.6e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 AFZ80702.1 - 1.5e-07 31.5 6.9 1.9e-07 31.2 3.9 1.9 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 AFZ80702.1 - 2.5e-06 26.3 0.2 0.00026 19.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family EIIA-man PF03610.11 AFZ80703.1 - 0.0048 16.9 0.2 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 PTS system fructose IIA component CHASE3 PF05227.8 AFZ80703.1 - 1 9.0 7.1 0.61 9.7 0.9 2.7 3 0 0 3 3 3 0 CHASE3 domain TRL PF13146.1 AFZ80704.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 TRL-like protein family VCBS PF13517.1 AFZ80705.1 - 2.6e-19 69.3 18.8 1.2e-06 28.7 0.2 5.7 4 2 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 AFZ80705.1 - 4.5e-18 64.3 11.8 0.00022 20.7 0.0 7.0 7 0 0 7 7 7 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 AFZ80705.1 - 1.1e-08 34.7 2.9 0.026 13.9 0.0 5.2 5 1 1 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region Hydrolase_3 PF08282.7 AFZ80706.1 - 4e-36 124.8 0.0 1.7e-35 122.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AFZ80706.1 - 1.4e-06 27.8 0.0 0.03 13.6 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 AFZ80706.1 - 0.0019 18.3 0.5 0.0066 16.6 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 AFZ80706.1 - 0.005 16.7 0.0 0.025 14.4 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AFZ80706.1 - 0.086 13.2 0.0 1.6 9.1 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ABC_tran PF00005.22 AFZ80707.1 - 7.1e-30 104.0 0.0 2e-16 60.5 0.0 2.6 2 1 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 AFZ80707.1 - 5.2e-06 26.5 0.1 0.015 15.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 AFZ80707.1 - 2.8e-05 24.2 3.2 0.053 13.4 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 AFZ80707.1 - 0.00011 21.6 0.9 0.11 11.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ArgK PF03308.11 AFZ80707.1 - 0.00023 20.0 0.4 0.0006 18.6 0.0 1.7 2 0 0 2 2 2 1 ArgK protein AAA_30 PF13604.1 AFZ80707.1 - 0.00024 20.7 0.1 0.061 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AFZ80707.1 - 0.00035 20.0 0.0 0.076 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AFZ80707.1 - 0.00041 21.1 0.0 0.21 12.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AFZ80707.1 - 0.00054 18.9 0.5 0.62 8.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 AFZ80707.1 - 0.0018 17.4 0.4 0.098 11.8 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 AFZ80707.1 - 0.0023 18.2 3.4 0.99 9.6 0.4 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 AFZ80707.1 - 0.0034 17.0 0.6 0.79 9.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 AFZ80707.1 - 0.0036 16.8 0.3 0.58 9.5 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 AFZ80707.1 - 0.0048 17.0 0.0 3.4 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 AFZ80707.1 - 0.0053 17.2 0.1 4.1 7.9 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 AFZ80707.1 - 0.0058 16.9 0.1 0.89 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 AFZ80707.1 - 0.0076 16.0 2.8 0.15 11.9 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function DUF87 UPF0079 PF02367.12 AFZ80707.1 - 0.011 15.3 0.9 0.28 10.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 AFZ80707.1 - 0.011 15.4 1.1 3.5 7.4 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 AFZ80707.1 - 0.011 15.4 0.4 3.3 7.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 AFZ80707.1 - 0.012 14.7 0.2 5.4 6.0 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin SMC_N PF02463.14 AFZ80707.1 - 0.032 13.4 0.5 0.35 10.0 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 AFZ80707.1 - 0.04 13.8 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 AFZ80707.1 - 0.053 13.4 0.2 0.35 10.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 AFZ80707.1 - 0.075 12.8 0.2 16 5.2 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_10 PF12846.2 AFZ80707.1 - 0.14 11.5 0.7 5.9 6.2 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain AAA_33 PF13671.1 AFZ80707.1 - 0.16 11.8 0.1 9.8 6.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 AFZ80707.1 - 0.2 11.0 2.0 10 5.5 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3671 PF12420.3 AFZ80708.1 - 0.089 12.7 11.5 3 7.8 7.9 2.2 1 1 0 1 1 1 0 Protein of unknown function EmrE PF13536.1 AFZ80708.1 - 1.1 9.5 12.2 1.9 8.7 8.5 1.4 1 1 0 1 1 1 0 Multidrug resistance efflux transporter FAINT PF04385.10 AFZ80710.1 - 1.5e-05 24.7 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function, DUF529 MMR_HSR1 PF01926.18 AFZ80712.1 - 4.3e-14 52.4 1.1 4.6e-13 49.1 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase GN3L_Grn1 PF08701.6 AFZ80712.1 - 7.2e-08 32.2 16.5 7.2e-08 32.2 11.4 2.8 2 1 0 2 2 2 1 GNL3L/Grn1 putative GTPase FeoB_N PF02421.13 AFZ80712.1 - 0.00016 20.9 0.5 0.00038 19.7 0.1 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 AFZ80712.1 - 0.00027 20.1 0.1 0.00085 18.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 AFZ80712.1 - 0.0009 18.7 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.14 AFZ80712.1 - 0.0014 18.0 0.2 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.11 AFZ80712.1 - 0.0018 17.3 0.4 0.0056 15.8 0.1 1.9 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 AFZ80712.1 - 0.0028 18.1 0.0 0.011 16.2 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 AFZ80712.1 - 0.0079 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 AFZ80712.1 - 0.029 14.1 8.7 0.41 10.4 0.1 3.5 2 2 1 3 3 3 0 Dynamin family AAA_16 PF13191.1 AFZ80712.1 - 0.047 13.6 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.17 AFZ80712.1 - 0.053 12.9 0.3 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Ras family CN_hydrolase PF00795.17 AFZ80712.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase AATF-Che1 PF13339.1 AFZ80713.1 - 0.044 13.9 1.1 0.14 12.2 0.3 2.0 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor GLE1 PF07817.8 AFZ80713.1 - 0.11 11.3 1.1 3.7 6.3 0.1 2.4 2 0 0 2 2 2 0 GLE1-like protein CesA PF11439.3 AFZ80713.1 - 0.25 11.3 0.1 0.25 11.3 0.1 2.7 3 0 0 3 3 3 0 Type III secretion system filament chaperone CesA MFS_1 PF07690.11 AFZ80714.1 - 3.7e-09 35.7 13.3 3.7e-09 35.7 9.2 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily AhpC-TSA PF00578.16 AFZ80715.1 - 1.2e-35 121.8 0.0 1.6e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AFZ80715.1 - 3.6e-14 52.5 0.0 4.2e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 AFZ80715.1 - 2.7e-08 33.3 0.1 4.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin FAINT PF04385.10 AFZ80716.1 - 2.2e-05 24.2 0.0 5.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function, DUF529 dCMP_cyt_deam_2 PF08211.6 AFZ80716.1 - 0.01 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region BBS2_Mid PF14783.1 AFZ80716.1 - 0.13 12.0 0.4 0.96 9.2 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region RRM_1 PF00076.17 AFZ80718.1 - 5.5e-25 86.7 1.3 1.3e-16 59.9 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ80718.1 - 3e-16 59.1 0.1 3.5e-10 39.7 0.0 4.1 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ80718.1 - 9.9e-13 47.7 1.4 0.00086 19.1 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP PF00188.21 AFZ80718.1 - 0.025 15.0 0.1 0.087 13.3 0.0 1.9 2 0 0 2 2 2 0 Cysteine-rich secretory protein family Snurportin1 PF11538.3 AFZ80719.1 - 3 7.6 7.9 9.6 6.0 0.7 2.2 2 0 0 2 2 2 0 Snurportin1 PHD PF00628.24 AFZ80720.1 - 2.2e-18 65.6 57.7 6.4e-09 35.3 8.1 3.9 3 1 2 5 5 5 3 PHD-finger PHD_2 PF13831.1 AFZ80720.1 - 0.00044 19.5 2.9 0.00044 19.5 2.0 6.0 4 2 0 4 4 4 2 PHD-finger zf-piccolo PF05715.8 AFZ80720.1 - 0.0082 16.1 6.7 0.0082 16.1 4.6 4.0 2 1 2 4 4 4 1 Piccolo Zn-finger C1_1 PF00130.17 AFZ80720.1 - 2.7 7.7 59.6 0.11 12.2 6.5 5.6 3 2 3 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Adenylsucc_synt PF00709.16 AFZ80721.1 - 1.3e-150 501.7 0.0 1.5e-150 501.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ribosomal_L30 PF00327.15 AFZ80722.1 - 0.017 14.7 0.0 0.053 13.1 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e AAA PF00004.24 AFZ80723.1 - 8.4e-45 152.2 0.0 4e-44 150.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AFZ80723.1 - 1.9e-08 34.1 0.1 8.8e-08 31.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AFZ80723.1 - 2.3e-07 30.8 0.0 7.9e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AFZ80723.1 - 3.4e-06 27.2 0.7 0.00094 19.3 0.5 2.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AFZ80723.1 - 1.4e-05 25.8 0.0 8.3e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AFZ80723.1 - 3.2e-05 23.9 0.1 0.00013 22.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 AFZ80723.1 - 5.7e-05 22.1 0.0 0.00013 21.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 AFZ80723.1 - 7e-05 21.9 0.0 0.00025 20.1 0.0 1.9 2 1 1 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 AFZ80723.1 - 0.0002 20.8 0.1 0.06 12.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 AFZ80723.1 - 0.0003 20.7 0.0 0.00069 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AFZ80723.1 - 0.00035 20.4 0.2 0.0011 18.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AFZ80723.1 - 0.0004 20.0 0.0 0.0009 18.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 AFZ80723.1 - 0.00083 18.8 0.0 0.0021 17.4 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 AFZ80723.1 - 0.0011 19.2 0.1 0.0052 17.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 AFZ80723.1 - 0.0016 18.1 0.2 0.086 12.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 AFZ80723.1 - 0.0016 17.6 0.2 0.0039 16.3 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 AFZ80723.1 - 0.0017 18.5 0.0 0.0052 16.9 0.0 1.9 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.8 AFZ80723.1 - 0.0021 16.8 0.0 0.0059 15.3 0.0 1.8 1 1 1 2 2 2 1 TIP49 C-terminus AAA_24 PF13479.1 AFZ80723.1 - 0.0027 17.3 0.1 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AFZ80723.1 - 0.0033 16.8 0.8 0.024 14.0 0.1 2.1 1 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 AFZ80723.1 - 0.0079 15.9 0.0 0.26 10.9 0.0 2.8 3 0 0 3 3 3 1 NTPase AAA_33 PF13671.1 AFZ80723.1 - 0.0084 15.9 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 AFZ80723.1 - 0.018 13.9 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 AFZ80723.1 - 0.024 13.5 0.1 0.053 12.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF2524 PF10732.4 AFZ80723.1 - 0.024 14.7 0.2 0.045 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Zeta_toxin PF06414.7 AFZ80723.1 - 0.03 13.4 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 AFZ80723.1 - 0.032 14.2 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 AFZ80723.1 - 0.039 13.5 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 AFZ80723.1 - 0.047 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 AFZ80723.1 - 0.06 12.9 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 AFZ80723.1 - 0.064 13.1 0.0 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase Arch_ATPase PF01637.13 AFZ80723.1 - 0.21 11.2 2.3 1.3 8.6 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase AAA_23 PF13476.1 AFZ80723.1 - 0.72 10.1 6.8 2.7 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 AFZ80724.1 - 3.6e-67 226.2 0.2 6.6e-67 225.4 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AFZ80724.1 - 7.9e-11 41.6 0.0 3.9e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ80724.1 - 5.4e-06 26.3 1.3 0.00048 20.0 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AFZ80724.1 - 9.3e-06 25.2 0.0 0.0018 17.7 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Stimulus_sens_1 PF13756.1 AFZ80724.1 - 0.17 12.2 0.1 81 3.6 0.0 3.5 4 0 0 4 4 4 0 Stimulus-sensing domain FAINT PF04385.10 AFZ80725.1 - 1.8e-19 69.3 19.6 1.8e-06 27.6 0.6 5.0 4 1 0 4 4 4 4 Domain of unknown function, DUF529 CDC45 PF02724.9 AFZ80725.1 - 0.015 13.4 4.6 0.025 12.6 3.2 1.3 1 0 0 1 1 1 0 CDC45-like protein TrmE_N PF10396.4 AFZ80726.1 - 2.8e-30 104.5 0.0 1.4e-29 102.3 0.0 2.1 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 AFZ80726.1 - 7e-21 74.3 0.0 2.2e-20 72.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 AFZ80726.1 - 2.1e-17 63.2 0.3 1.9e-16 60.2 0.0 2.5 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 AFZ80726.1 - 5.8e-09 35.4 0.0 9.1e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AFZ80726.1 - 2.6e-05 24.1 0.1 0.00016 21.5 0.1 2.1 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 AFZ80726.1 - 2.9e-05 24.5 0.0 0.00011 22.6 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AFZ80726.1 - 0.00038 19.7 0.3 0.13 11.5 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AFZ80726.1 - 0.00058 19.0 0.2 0.00099 18.3 0.2 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AIG1 PF04548.11 AFZ80726.1 - 0.016 14.2 0.4 0.028 13.5 0.3 1.4 1 0 0 1 1 1 0 AIG1 family Ras PF00071.17 AFZ80726.1 - 0.023 14.0 0.1 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 Ras family DUF4496 PF14908.1 AFZ80726.1 - 0.026 14.4 0.0 0.16 11.8 0.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4496) DASH_Dad4 PF08650.5 AFZ80726.1 - 0.19 11.6 3.9 0.13 12.1 0.9 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad4 Hus1 PF04005.7 AFZ80727.1 - 3.3e-16 59.0 0.1 3.8e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein Sod_Fe_C PF02777.13 AFZ80728.1 - 4.5e-31 106.8 4.3 1.9e-30 104.8 0.3 2.2 1 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 AFZ80728.1 - 2.5e-16 59.7 8.5 2.4e-12 46.9 0.1 3.2 2 1 1 3 3 3 2 Iron/manganese superoxide dismutases, alpha-hairpin domain PG_binding_3 PF09374.5 AFZ80728.1 - 0.096 12.6 0.4 9.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Predicted Peptidoglycan domain FAINT PF04385.10 AFZ80729.1 - 1.4e-06 28.0 0.1 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80730.1 - 1.4e-06 28.0 0.1 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function, DUF529 PPR_2 PF13041.1 AFZ80731.1 - 2.4e-39 133.0 14.4 4.4e-12 45.7 0.0 8.9 3 2 7 10 10 10 8 PPR repeat family PPR_3 PF13812.1 AFZ80731.1 - 8.6e-25 84.9 0.1 1.7e-05 24.7 0.0 8.8 9 0 0 9 9 9 6 Pentatricopeptide repeat domain PPR PF01535.15 AFZ80731.1 - 4.4e-24 82.7 15.0 9.6e-05 22.1 0.0 8.7 9 0 0 9 9 9 6 PPR repeat PPR_1 PF12854.2 AFZ80731.1 - 1.7e-15 56.2 2.1 7.5e-05 22.1 0.0 5.9 7 0 0 7 7 7 3 PPR repeat ATP13 PF12921.2 AFZ80731.1 - 0.032 13.6 0.2 0.032 13.6 0.1 2.8 4 0 0 4 4 4 0 Mitochondrial ATPase expression TPR_7 PF13176.1 AFZ80731.1 - 0.063 13.1 0.1 24 5.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MNE1 PF13762.1 AFZ80731.1 - 0.13 12.3 3.9 1.1 9.3 0.1 3.8 2 1 1 4 4 4 0 Mitochondrial splicing apparatus component COX6B PF02297.12 AFZ80732.1 - 0.013 15.5 5.5 0.013 15.5 3.8 1.4 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb ASXH PF13919.1 AFZ80733.1 - 0.069 12.9 0.1 0.069 12.9 0.1 2.0 2 0 0 2 2 2 0 Asx homology domain Pkinase PF00069.20 AFZ80734.1 - 7.3e-36 123.6 0.0 1.1e-19 70.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ80734.1 - 2.2e-14 53.1 0.0 5.8e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AFZ80734.1 - 0.00017 20.6 0.0 0.062 12.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.4 AFZ80734.1 - 0.0019 17.5 0.0 0.0074 15.6 0.0 2.0 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 AFZ80734.1 - 0.005 15.9 0.0 0.0086 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CBFD_NFYB_HMF PF00808.18 AFZ80736.1 - 2e-16 59.7 0.2 3e-16 59.2 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AFZ80736.1 - 1.6e-15 56.9 0.1 2.9e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 AFZ80736.1 - 0.027 14.4 0.2 0.063 13.2 0.1 1.6 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) Sec63 PF02889.11 AFZ80737.1 - 7.4e-81 271.7 1.3 4.7e-48 164.0 0.2 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 AFZ80737.1 - 3.7e-55 185.9 0.0 3.7e-27 94.8 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ80737.1 - 2.4e-20 72.1 0.1 6.1e-09 35.6 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ80737.1 - 3.1e-20 72.7 0.0 3.6e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AFZ80737.1 - 2.3e-09 37.4 0.0 0.0046 17.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 AFZ80737.1 - 1.4e-07 31.7 0.4 0.026 14.7 0.2 3.8 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 AFZ80737.1 - 8.4e-05 21.8 0.0 0.082 12.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein T2SE PF00437.15 AFZ80737.1 - 0.00066 18.6 0.0 1 8.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF2075 PF09848.4 AFZ80737.1 - 0.001 18.1 0.0 0.26 10.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 AFZ80737.1 - 0.0026 17.4 0.0 1.7 8.4 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 AFZ80737.1 - 0.0061 15.8 0.6 5.5 6.1 0.0 3.6 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain AAA_18 PF13238.1 AFZ80737.1 - 0.016 15.5 0.0 0.079 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 AFZ80737.1 - 0.024 14.0 0.0 14 5.0 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_11 PF13086.1 AFZ80737.1 - 0.16 11.5 0.0 0.66 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sad1_UNC PF07738.8 AFZ80738.1 - 7e-16 58.2 1.5 1.6e-15 57.1 0.2 2.3 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Ribosomal_L33 PF00471.15 AFZ80739.1 - 4.2e-09 36.5 1.9 4.2e-09 36.4 0.1 1.9 2 1 1 3 3 3 1 Ribosomal protein L33 DUF2976 PF11190.3 AFZ80740.1 - 0.0016 17.9 0.1 0.0046 16.4 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2976) FAST_1 PF06743.10 AFZ80741.1 - 0.052 13.2 3.2 0.087 12.5 0.1 2.9 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 CLASP_N PF12348.3 AFZ80742.1 - 0.0043 16.4 0.3 0.0072 15.7 0.2 1.3 1 0 0 1 1 1 1 CLASP N terminal Proteasome PF00227.21 AFZ80743.1 - 1.1e-53 181.3 0.3 1.6e-53 180.8 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AFZ80743.1 - 4.5e-13 48.2 0.0 7.7e-13 47.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RAP PF08373.5 AFZ80744.1 - 2.7e-16 59.0 0.1 6.5e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 RAP domain RRM_1 PF00076.17 AFZ80745.1 - 3.1e-15 55.5 0.0 5.7e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ80745.1 - 2.3e-10 40.3 0.0 4.7e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 AFZ80745.1 - 0.00012 22.0 0.3 0.00041 20.3 0.0 2.1 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.1 AFZ80745.1 - 0.043 13.6 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP PF00188.21 AFZ80747.1 - 0.027 14.9 1.0 0.091 13.2 0.0 2.2 2 1 0 2 2 2 0 Cysteine-rich secretory protein family FAINT PF04385.10 AFZ80748.1 - 0.00074 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80748.1 - 0.24 10.8 0.0 0.38 10.1 0.0 1.2 1 0 0 1 1 1 0 Merozoite Antigen PDGLE PF13190.1 AFZ80748.1 - 0.26 10.9 1.3 0.72 9.5 0.0 2.3 2 0 0 2 2 2 0 PDGLE domain DUF3040 PF11239.3 AFZ80749.1 - 4.8 7.3 5.1 2.6 8.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) zf-CCCH PF00642.19 AFZ80751.1 - 0.0069 16.0 0.8 0.0069 16.0 0.6 3.8 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FAINT PF04385.10 AFZ80754.1 - 4.9e-15 55.1 7.5 1e-06 28.4 0.2 4.4 3 0 0 3 3 3 2 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 AFZ80754.1 - 9.6e-11 41.9 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ80754.1 - 1.2e-09 37.9 1.1 7.1e-08 32.1 0.2 2.6 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 AFZ80754.1 - 2.2e-06 27.4 0.0 6.5e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AFZ80754.1 - 0.0004 19.6 1.0 0.0011 18.2 0.0 2.2 3 0 0 3 3 3 1 Prolyl oligopeptidase family LIP PF03583.9 AFZ80754.1 - 0.029 13.5 0.0 0.084 12.0 0.0 1.7 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_3 PF07859.8 AFZ80754.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAINT PF04385.10 AFZ80755.1 - 2.5e-24 84.9 0.8 5.6e-07 29.3 0.1 3.6 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80755.1 - 0.0023 17.4 2.5 0.17 11.3 0.0 3.0 1 1 2 3 3 3 2 Merozoite Antigen FAINT PF04385.10 AFZ80757.1 - 1.9e-17 62.8 2.3 1.1e-05 25.1 0.4 4.0 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 AFZ80757.1 - 1.7e-09 37.8 0.0 3.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ80757.1 - 3.6e-08 33.2 0.0 8.3e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ80757.1 - 1.1e-07 31.5 0.0 5.7e-07 29.3 0.0 2.2 3 0 0 3 3 3 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 AFZ80757.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAINT PF04385.10 AFZ80759.1 - 2.2e-28 97.8 9.1 1.9e-07 30.7 0.1 6.1 6 1 0 6 6 6 5 Domain of unknown function, DUF529 Thioredoxin_8 PF13905.1 AFZ80759.1 - 2.5 8.2 10.2 34 4.6 0.1 4.1 4 0 0 4 4 4 0 Thioredoxin-like FAINT PF04385.10 AFZ80760.1 - 1.5e-09 37.5 0.0 8.5e-06 25.5 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80761.1 - 3e-20 71.8 10.0 2.9e-06 27.0 0.6 3.7 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 AFZ80761.1 - 2.4e-19 70.1 0.0 8.7e-19 68.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ80761.1 - 8.4e-14 51.5 0.0 5.1e-13 49.0 0.0 2.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ80761.1 - 1.6e-08 34.3 0.2 5.4e-07 29.3 0.1 2.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 AFZ80761.1 - 1.7e-06 27.7 0.1 2e-05 24.2 0.0 2.5 2 1 1 3 3 3 1 alpha/beta hydrolase fold DUF2424 PF10340.4 AFZ80761.1 - 2.2e-05 23.3 0.4 0.00094 17.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_4 PF08386.5 AFZ80761.1 - 6.2e-05 22.8 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.11 AFZ80761.1 - 0.0035 16.8 0.0 0.043 13.2 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase zf-CCHC PF00098.18 AFZ80762.1 - 7.4e-09 35.1 6.0 0.00031 20.5 0.2 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 AFZ80762.1 - 0.00013 21.5 7.3 0.086 12.5 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.1 AFZ80762.1 - 0.00068 19.0 11.9 0.019 14.4 1.1 2.8 3 0 0 3 3 3 2 GAG-polyprotein viral zinc-finger Gmx_para_CXXCG PF09535.5 AFZ80762.1 - 0.011 14.7 1.1 0.016 14.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) DUF2296 PF10058.4 AFZ80762.1 - 0.016 14.9 2.2 0.031 13.9 1.5 1.5 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) GerPC PF10737.4 AFZ80762.1 - 0.019 14.7 1.4 0.026 14.3 1.0 1.4 1 1 0 1 1 1 0 Spore germination protein GerPC HR1 PF02185.11 AFZ80762.1 - 0.02 14.6 3.3 0.051 13.3 2.3 1.6 1 0 0 1 1 1 0 Hr1 repeat DivIC PF04977.10 AFZ80762.1 - 0.04 13.4 1.8 0.068 12.6 1.2 1.4 1 0 0 1 1 1 0 Septum formation initiator zf-CCHC_2 PF13696.1 AFZ80762.1 - 0.04 13.4 2.4 0.16 11.4 0.1 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF2677 PF10838.3 AFZ80762.1 - 0.084 12.5 0.4 0.15 11.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2677) TBPIP PF07106.8 AFZ80762.1 - 0.82 9.2 8.7 12 5.3 6.0 2.1 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-UBR PF02207.15 AFZ80762.1 - 0.86 9.3 8.4 5.8 6.7 5.8 2.1 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) XPA_N PF01286.13 AFZ80762.1 - 0.93 9.2 5.0 13 5.6 0.0 3.0 2 1 1 3 3 3 0 XPA protein N-terminal zf-CCHC_3 PF13917.1 AFZ80762.1 - 1 9.1 11.3 2.6 7.8 2.1 2.5 1 1 1 2 2 2 0 Zinc knuckle IBR PF01485.16 AFZ80762.1 - 1.7 8.5 10.3 1.3e+02 2.5 7.2 2.6 1 1 0 1 1 1 0 IBR domain zf-CCHC PF00098.18 AFZ80764.1 - 3.7e-11 42.3 8.2 1.8e-05 24.4 0.2 2.1 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 AFZ80764.1 - 1.8e-05 24.3 6.9 0.0044 16.6 1.0 2.1 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 AFZ80764.1 - 0.0021 17.4 0.3 0.0021 17.4 0.2 2.2 1 1 1 2 2 2 1 Zinc knuckle DUF4206 PF13901.1 AFZ80764.1 - 0.031 13.8 2.0 0.032 13.7 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) Tenui_NS3 PF05310.7 AFZ80764.1 - 0.14 12.0 0.2 0.15 11.9 0.1 1.0 1 0 0 1 1 1 0 Tenuivirus movement protein eIF3g PF12353.3 AFZ80764.1 - 2.7 7.9 5.0 0.71 9.7 0.2 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-DHHC PF01529.15 AFZ80765.1 - 1.3e-31 109.2 17.2 3.2e-31 108.0 10.8 2.4 3 0 0 3 3 3 1 DHHC palmitoyltransferase Daxx PF03344.10 AFZ80765.1 - 0.056 11.9 9.7 0.081 11.4 6.7 1.1 1 0 0 1 1 1 0 Daxx Family DUF2413 PF10310.4 AFZ80765.1 - 0.12 11.1 6.4 0.2 10.4 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CDC45 PF02724.9 AFZ80765.1 - 6.4 4.6 5.3 9.6 4.0 3.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_11 PF08241.7 AFZ80766.1 - 6.9e-14 52.1 0.0 1.2e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AFZ80766.1 - 4.6e-10 39.4 0.0 1.1e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AFZ80766.1 - 3.1e-07 30.1 0.1 5.3e-07 29.3 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AFZ80766.1 - 5.5e-06 26.7 0.0 9.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AFZ80766.1 - 6.1e-06 26.5 0.2 3.6e-05 24.0 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 AFZ80766.1 - 3.1e-05 23.6 0.1 4.5e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_18 PF12847.2 AFZ80766.1 - 0.02 15.4 0.2 0.07 13.7 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 AFZ80766.1 - 0.049 12.7 0.1 0.27 10.3 0.1 1.9 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 AFZ80766.1 - 0.078 13.0 0.0 0.56 10.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 AFZ80766.1 - 0.095 11.7 0.0 0.31 10.1 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ebp2 PF05890.7 AFZ80767.1 - 3.3e-20 72.5 29.8 3.3e-20 72.5 20.6 2.3 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Lge1 PF11488.3 AFZ80767.1 - 0.011 15.8 0.3 4.1 7.6 0.2 2.9 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Thiol-ester_cl PF10569.4 AFZ80767.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha-macro-globulin thiol-ester bond-forming region V_ATPase_I PF01496.14 AFZ80767.1 - 3.7 5.2 6.6 5.6 4.6 4.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Brix PF04427.13 AFZ80768.1 - 1.1e-31 110.0 0.0 3.3e-31 108.4 0.0 1.8 1 1 0 1 1 1 1 Brix domain Nop14 PF04147.7 AFZ80769.1 - 0.15 9.9 7.3 0.21 9.4 5.1 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 AFZ80769.1 - 0.45 8.9 7.8 0.83 8.0 5.4 1.3 1 0 0 1 1 1 0 Daxx Family Josephin PF02099.12 AFZ80771.1 - 8.7e-17 61.1 0.0 1.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Josephin UBX PF00789.15 AFZ80771.1 - 0.0037 17.3 0.0 0.0086 16.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain s48_45 PF07422.8 AFZ80772.1 - 0.00098 19.1 5.6 0.066 13.3 0.1 4.1 4 1 0 4 4 4 2 Sexual stage antigen s48/45 domain FAINT PF04385.10 AFZ80773.1 - 9.4e-15 54.2 4.7 3.6e-10 39.5 0.2 2.8 2 1 1 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80774.1 - 0.0034 17.1 0.6 0.007 16.1 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function, DUF529 EF-hand_7 PF13499.1 AFZ80776.1 - 2.6e-06 27.4 0.4 0.00018 21.5 0.3 2.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 AFZ80776.1 - 2.7e-06 26.7 1.0 0.042 13.7 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 AFZ80776.1 - 8.4e-06 25.3 3.6 0.24 11.0 0.2 4.3 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 AFZ80776.1 - 2e-05 23.5 3.5 0.48 9.8 0.0 4.1 5 0 0 5 5 5 3 EF hand FAINT PF04385.10 AFZ80777.1 - 8.4e-08 31.9 3.1 6.9e-05 22.6 0.1 2.9 3 0 0 3 3 3 2 Domain of unknown function, DUF529 Sec8_exocyst PF04048.9 AFZ80778.1 - 0.43 10.1 10.0 0.085 12.4 0.6 3.5 2 1 2 4 4 4 0 Sec8 exocyst complex component specific domain Tim54 PF11711.3 AFZ80779.1 - 0.16 10.5 2.2 0.28 9.7 1.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HSBP1 PF06825.7 AFZ80780.1 - 0.076 12.5 0.4 0.15 11.6 0.3 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Mitofilin PF09731.4 AFZ80780.1 - 1.6 7.2 34.0 2.1 6.8 23.5 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FAINT PF04385.10 AFZ80781.1 - 1.7e-23 82.2 9.6 4.2e-08 32.9 0.1 5.0 4 0 0 4 4 4 4 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80782.1 - 1.7e-06 27.7 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Herpes_BLLF1 PF05109.8 AFZ80782.1 - 0.026 12.5 0.7 0.03 12.2 0.5 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Tn7_Tnp_TnsA_N PF08722.6 AFZ80784.1 - 0.099 12.6 2.1 2 8.4 1.5 2.4 1 1 0 1 1 1 0 TnsA endonuclease N terminal FAINT PF04385.10 AFZ80787.1 - 0.021 14.6 1.4 0.33 10.8 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function, DUF529 Hexokinase_1 PF00349.16 AFZ80789.1 - 8e-60 201.6 0.0 1e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 AFZ80789.1 - 1.9e-47 161.5 0.0 2.6e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FAINT PF04385.10 AFZ80791.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Ribosomal_L3 PF00297.17 AFZ80792.1 - 1.9e-107 358.5 5.8 2.2e-107 358.3 4.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 FadA PF09403.5 AFZ80792.1 - 0.14 12.1 0.7 0.24 11.4 0.5 1.3 1 0 0 1 1 1 0 Adhesion protein FadA PDGLE PF13190.1 AFZ80793.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 PDGLE domain Gag_spuma PF03276.9 AFZ80793.1 - 9.4 4.4 7.1 14 3.8 4.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Syndecan PF01034.15 AFZ80795.1 - 0.058 13.0 2.3 0.12 12.0 1.6 1.5 1 0 0 1 1 1 0 Syndecan domain DUF3507 PF12015.3 AFZ80795.1 - 0.11 11.9 0.1 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3507) Gly-zipper_YMGG PF13441.1 AFZ80795.1 - 0.12 11.9 1.1 0.19 11.2 0.7 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper FAINT PF04385.10 AFZ80798.1 - 2.1e-19 69.1 5.7 1.9e-09 37.1 0.0 4.2 4 1 1 5 5 5 3 Domain of unknown function, DUF529 DUF4430 PF14478.1 AFZ80798.1 - 0.23 11.5 1.8 0.7 9.9 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4430) FAINT PF04385.10 AFZ80800.1 - 2.9e-22 78.3 0.3 7.4e-08 32.1 0.0 4.6 4 0 0 4 4 4 4 Domain of unknown function, DUF529 ENTH PF01417.15 AFZ80803.1 - 4.1e-25 88.0 0.0 6e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 ENTH domain Cpl-7 PF08230.6 AFZ80803.1 - 0.15 11.7 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Cpl-7 lysozyme C-terminal domain SR-25 PF10500.4 AFZ80803.1 - 0.18 11.2 10.7 0.28 10.6 7.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAINT PF04385.10 AFZ80805.1 - 1.6e-08 34.2 0.9 2.7e-08 33.5 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 EMG1 PF03587.9 AFZ80808.1 - 2.9e-28 98.5 0.1 4.7e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase LTV PF04180.9 AFZ80810.1 - 0.18 11.3 3.2 0.19 11.2 1.6 1.4 1 1 1 2 2 2 0 Low temperature viability protein Cys_rich_CPXG PF14255.1 AFZ80811.1 - 0.29 10.9 2.0 0.74 9.6 1.4 1.7 1 0 0 1 1 1 0 Cysteine-rich CPXCG TFIIS_M PF07500.9 AFZ80812.1 - 5.6e-25 87.6 0.9 5.6e-25 87.6 0.7 1.9 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 AFZ80812.1 - 2.1e-17 62.4 6.4 3.8e-17 61.6 4.4 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 AFZ80812.1 - 2.2e-10 39.8 0.9 5.7e-10 38.5 0.6 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Snapin_Pallidin PF14712.1 AFZ80812.1 - 0.0029 17.8 0.7 0.0086 16.3 0.5 1.8 1 0 0 1 1 1 1 Snapin/Pallidin Elf1 PF05129.8 AFZ80812.1 - 0.053 13.2 1.9 0.12 12.0 1.3 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DASH_Dad2 PF08654.5 AFZ80812.1 - 0.084 12.8 2.0 0.18 11.7 0.0 2.4 2 1 1 3 3 3 0 DASH complex subunit Dad2 FAINT PF04385.10 AFZ80813.1 - 2.7e-28 97.6 18.4 1.4e-07 31.2 0.1 6.4 6 0 0 6 6 6 6 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80813.1 - 3.5e-07 29.9 8.1 0.0015 18.0 2.2 4.4 4 1 1 5 5 5 4 Merozoite Antigen FAINT PF04385.10 AFZ80814.1 - 8.6e-16 57.5 18.9 1e-05 25.2 0.0 5.0 5 0 0 5 5 5 4 Domain of unknown function, DUF529 Tox-SHH PF15652.1 AFZ80814.1 - 0.035 14.6 0.6 0.56 10.8 0.1 2.8 2 0 0 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature DUF3035 PF11233.3 AFZ80814.1 - 0.079 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) Choline_kinase PF01633.15 AFZ80815.1 - 1.8e-45 155.1 0.1 6.6e-45 153.2 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 AFZ80815.1 - 6.8e-13 48.9 0.0 9.4e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 AFZ80815.1 - 0.00012 21.2 0.0 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase ComZ PF10815.3 AFZ80815.1 - 0.1 12.4 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 ComZ WD40 PF00400.27 AFZ80819.1 - 1.5e-13 50.0 8.6 5e-07 29.3 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF3312 PF11768.3 AFZ80819.1 - 0.0005 18.4 0.1 0.0098 14.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3312) IKI3 PF04762.7 AFZ80819.1 - 0.044 11.6 0.1 1.5 6.5 0.0 2.0 2 0 0 2 2 2 0 IKI3 family HA2 PF04408.18 AFZ80821.1 - 4.4e-29 100.5 0.1 4.4e-29 100.5 0.1 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AFZ80821.1 - 8.2e-29 99.7 0.2 2.4e-28 98.2 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.18 AFZ80821.1 - 1.8e-10 40.7 0.7 5.6e-10 39.1 0.1 2.1 2 0 0 2 2 2 1 S1 RNA binding domain Helicase_C PF00271.26 AFZ80821.1 - 4.1e-10 39.3 0.0 1.4e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AFZ80821.1 - 1.5e-06 28.3 0.0 5.8e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 AFZ80821.1 - 0.00057 18.8 0.0 0.0015 17.4 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.24 AFZ80821.1 - 0.0011 18.5 0.0 0.0029 17.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 AFZ80821.1 - 0.084 12.4 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Bax1-I PF01027.15 AFZ80824.1 - 1.6e-14 54.0 34.0 1.8e-14 53.8 23.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 FAINT PF04385.10 AFZ80826.1 - 6e-07 29.2 0.1 6e-07 29.2 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80826.1 - 0.0017 17.8 0.0 0.0038 16.7 0.0 1.5 1 0 0 1 1 1 1 Merozoite Antigen Doppel PF11466.3 AFZ80826.1 - 0.095 12.2 2.1 0.16 11.5 1.4 1.3 1 0 0 1 1 1 0 Prion-like protein Doppel ABC_tran PF00005.22 AFZ80827.1 - 1.9e-31 109.1 0.0 1.7e-17 64.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 AFZ80827.1 - 7.6e-06 26.0 0.2 0.015 15.3 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 AFZ80827.1 - 1.1e-05 25.9 3.4 0.057 13.7 0.5 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AFZ80827.1 - 2.6e-05 23.6 0.7 0.064 12.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 AFZ80827.1 - 3.4e-05 23.3 0.0 0.031 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 AFZ80827.1 - 0.00013 21.6 0.2 0.027 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AFZ80827.1 - 0.00021 22.0 0.0 0.26 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 AFZ80827.1 - 0.00022 21.2 0.9 0.02 14.8 0.1 5.1 6 1 0 6 6 5 2 AAA domain Zeta_toxin PF06414.7 AFZ80827.1 - 0.00042 19.4 0.2 0.42 9.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 AFZ80827.1 - 0.00045 20.5 0.1 0.36 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 AFZ80827.1 - 0.00058 18.7 0.6 0.0015 17.3 0.0 1.8 2 0 0 2 2 2 1 ArgK protein DUF258 PF03193.11 AFZ80827.1 - 0.00077 18.6 0.3 0.09 11.9 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF87 PF01935.12 AFZ80827.1 - 0.0014 18.5 1.6 0.054 13.3 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 AFZ80827.1 - 0.0018 17.9 0.4 0.24 11.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 AFZ80827.1 - 0.0019 17.6 0.2 0.74 9.2 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family UPF0079 PF02367.12 AFZ80827.1 - 0.0031 17.1 0.7 0.16 11.6 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 AFZ80827.1 - 0.0035 17.0 0.4 2.2 7.8 0.1 2.6 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 AFZ80827.1 - 0.0038 16.4 0.2 0.15 11.2 0.0 2.6 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain T2SE PF00437.15 AFZ80827.1 - 0.0046 15.8 0.7 1.8 7.4 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.1 AFZ80827.1 - 0.0067 16.1 1.6 3.9 7.2 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 AFZ80827.1 - 0.012 15.7 0.0 5.8 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 AFZ80827.1 - 0.012 16.0 0.1 4.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein NB-ARC PF00931.17 AFZ80827.1 - 0.014 14.2 0.3 0.11 11.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 AFZ80827.1 - 0.019 14.4 1.8 3.7 6.9 0.1 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 AFZ80827.1 - 0.029 13.4 2.0 8.7 5.2 0.0 3.5 4 0 0 4 4 4 0 AAA ATPase domain MMR_HSR1 PF01926.18 AFZ80827.1 - 0.029 14.3 1.1 0.15 12.0 0.0 2.6 3 0 0 3 3 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 AFZ80827.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 AFZ80827.1 - 0.064 12.9 0.2 5.4 6.6 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_10 PF12846.2 AFZ80827.1 - 0.068 12.5 0.4 4.2 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 AFZ80827.1 - 0.072 12.9 0.1 6.8 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 AFZ80827.1 - 0.11 11.1 0.3 7.6 5.0 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF2791 PF10923.3 AFZ80827.1 - 0.17 10.4 0.0 2.9 6.3 0.0 2.5 3 0 0 3 3 3 0 P-loop Domain of unknown function (DUF2791) Dynamin_N PF00350.18 AFZ80827.1 - 0.22 11.3 2.7 3.5 7.4 0.0 2.6 3 0 0 3 3 2 0 Dynamin family FAINT PF04385.10 AFZ80828.1 - 2.2e-07 30.6 1.1 0.0002 21.1 0.0 3.2 2 1 0 2 2 2 2 Domain of unknown function, DUF529 DUF3775 PF12616.3 AFZ80828.1 - 0.04 13.7 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) A_deaminase PF00962.17 AFZ80829.1 - 9.6e-30 103.6 0.0 1e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Integrase_1 PF12835.2 AFZ80829.1 - 0.043 13.5 0.0 0.075 12.7 0.0 1.5 2 0 0 2 2 2 0 Integrase Antimicrobial_7 PF08102.6 AFZ80829.1 - 0.17 11.9 0.8 8.9 6.4 0.1 3.1 2 1 1 3 3 3 0 Scorpion antimicrobial peptide FAINT PF04385.10 AFZ80830.1 - 0.032 14.0 0.1 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, DUF529 hGDE_N PF14699.1 AFZ80830.1 - 0.14 12.0 0.1 1.3 8.8 0.0 2.4 3 1 0 3 3 3 0 N-terminal domain from the human glycogen debranching enzyme FAINT PF04385.10 AFZ80832.1 - 2.8e-22 78.3 3.2 1.8e-05 24.4 0.0 5.0 5 0 0 5 5 5 4 Domain of unknown function, DUF529 DUF1887 PF09002.6 AFZ80832.1 - 0.018 13.5 0.0 0.027 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) Spt4 PF06093.8 AFZ80833.1 - 3.8e-29 100.3 0.2 5e-29 100.0 0.1 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger GLE1 PF07817.8 AFZ80834.1 - 1.2e-07 30.9 5.6 2.1e-05 23.5 0.3 2.7 3 0 0 3 3 3 2 GLE1-like protein YkyA PF10368.4 AFZ80834.1 - 0.04 13.2 15.5 0.28 10.4 6.1 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Hydrolase_3 PF08282.7 AFZ80835.1 - 2.1e-38 132.3 0.0 2.4e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AFZ80835.1 - 3.7e-05 23.1 0.0 0.035 13.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 AFZ80835.1 - 0.0014 18.8 0.5 0.0064 16.6 0.3 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Abhydrolase_6 PF12697.2 AFZ80836.1 - 3.5e-14 53.2 0.0 5.6e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ80836.1 - 2.2e-11 43.6 0.0 5.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ80836.1 - 1.4e-08 34.4 0.1 4.5e-08 32.8 0.1 1.9 1 0 0 1 1 1 1 Putative lysophospholipase FAINT PF04385.10 AFZ80836.1 - 2.2e-06 27.4 7.7 0.09 12.6 0.4 5.0 4 0 0 4 4 4 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80836.1 - 6.8e-05 22.4 6.1 0.0038 16.7 0.1 3.1 3 0 0 3 3 3 2 Merozoite Antigen Abhydrolase_1 PF00561.15 AFZ80836.1 - 0.00043 19.9 0.2 0.062 12.8 0.1 3.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 AFZ80836.1 - 0.0015 17.5 0.0 0.006 15.5 0.0 2.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF2305 PF10230.4 AFZ80836.1 - 0.0078 15.6 0.1 0.019 14.4 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_4 PF08386.5 AFZ80836.1 - 0.034 14.0 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein PGAP1 PF07819.8 AFZ80836.1 - 0.052 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.7 AFZ80836.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PI3_PI4_kinase PF00454.22 AFZ80837.1 - 2e-27 96.1 0.1 1e-25 90.5 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 AFZ80837.1 - 3.3e-20 72.0 4.4 3.3e-20 72.0 3.1 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Thiolase_N PF00108.18 AFZ80838.1 - 2.3e-35 121.8 0.0 3.8e-35 121.1 0.0 1.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AFZ80838.1 - 5.1e-18 64.6 0.0 9.9e-18 63.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 AFZ80838.1 - 6.5e-05 22.5 0.0 0.0059 16.2 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HNH_4 PF13395.1 AFZ80838.1 - 0.052 13.1 0.1 4 7.1 0.0 2.5 2 0 0 2 2 2 0 HNH endonuclease ketoacyl-synt PF00109.21 AFZ80838.1 - 0.066 12.6 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain HTH_26 PF13443.1 AFZ80839.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.0 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Bax1-I PF01027.15 AFZ80840.1 - 4.5e-27 94.9 33.9 5.2e-27 94.7 23.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Reo_sigmaC PF04582.7 AFZ80841.1 - 2.5e-08 33.4 17.7 5e-05 22.6 6.4 3.4 2 1 1 3 3 3 2 Reovirus sigma C capsid protein Med9 PF07544.8 AFZ80841.1 - 0.0015 18.2 2.2 0.056 13.1 0.5 3.7 2 1 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF4164 PF13747.1 AFZ80841.1 - 0.033 14.3 0.9 5.8 7.1 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.7 AFZ80841.1 - 0.31 11.3 21.6 0.65 10.2 1.4 5.8 3 2 2 6 6 6 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 AFZ80841.1 - 0.31 10.6 3.3 4.4 6.8 0.2 3.1 2 1 1 3 3 3 0 IncA protein Laminin_II PF06009.7 AFZ80841.1 - 8.6 6.1 16.6 0.4 10.4 0.2 4.5 2 2 2 4 4 4 0 Laminin Domain II cwf21 PF08312.7 AFZ80843.1 - 3.4e-09 36.4 12.1 1.2e-08 34.7 8.4 2.0 1 0 0 1 1 1 1 cwf21 domain GTP_EFTU PF00009.22 AFZ80844.1 - 7.6e-61 204.8 0.1 1.2e-60 204.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AFZ80844.1 - 1.6e-35 121.2 0.0 5.4e-35 119.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 AFZ80844.1 - 2.3e-21 75.4 0.0 5.1e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 AFZ80844.1 - 1.5e-14 53.5 0.0 3e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 AFZ80844.1 - 5.3e-12 45.6 2.9 8.9e-12 44.9 0.1 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AFZ80844.1 - 0.00015 21.6 0.0 0.00036 20.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-Nse PF11789.3 AFZ80845.1 - 3.4e-14 52.0 2.2 6.2e-14 51.2 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Chal_sti_synt_C PF02797.10 AFZ80845.1 - 0.0037 17.1 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain zf-RING_UBOX PF13445.1 AFZ80845.1 - 0.069 12.8 0.7 0.3 10.8 0.5 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 AFZ80845.1 - 0.082 12.4 1.6 0.21 11.1 1.1 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Rop PF01815.11 AFZ80845.1 - 0.29 10.6 2.2 0.34 10.3 0.3 2.0 2 0 0 2 2 2 0 Rop protein SIR2 PF02146.12 AFZ80846.1 - 1e-27 96.9 0.0 1.6e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family V-SNARE_C PF12352.3 AFZ80847.1 - 1.9e-07 31.0 2.7 4.6e-07 29.8 1.9 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus RVT_N PF13655.1 AFZ80847.1 - 0.044 13.8 2.4 0.047 13.7 0.5 1.8 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase DP PF08781.5 AFZ80847.1 - 0.05 13.2 2.3 0.11 12.2 1.6 1.5 1 0 0 1 1 1 0 Transcription factor DP ApoC-I PF04691.7 AFZ80847.1 - 0.078 12.6 0.1 0.71 9.6 0.1 2.4 1 1 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) Lebercilin PF15619.1 AFZ80847.1 - 0.51 9.7 9.2 1.8 7.9 4.8 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Sec2p PF06428.6 AFZ80847.1 - 0.55 10.1 5.1 0.56 10.0 1.1 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p NPV_P10 PF05531.7 AFZ80847.1 - 1 9.6 5.7 1.7 8.9 0.9 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 AFZ80847.1 - 1.8 8.3 9.9 0.14 11.9 1.2 2.3 1 1 1 2 2 2 0 Laminin Domain II RPA_interact_M PF14767.1 AFZ80847.1 - 1.8 9.3 7.5 0.24 12.1 1.5 2.2 2 1 0 2 2 2 0 Replication protein A interacting middle CDC37_N PF03234.9 AFZ80848.1 - 0.00023 21.5 0.7 0.00023 21.5 0.5 2.0 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CS PF04969.11 AFZ80848.1 - 0.00023 21.6 0.0 0.00066 20.1 0.0 1.8 1 0 0 1 1 1 1 CS domain DUF222 PF02720.12 AFZ80850.1 - 0.056 12.5 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF222) HAUS-augmin3 PF14932.1 AFZ80850.1 - 0.075 12.2 0.1 0.075 12.2 0.0 2.6 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 Antimicrobial_2 PF08023.7 AFZ80850.1 - 0.16 12.2 4.9 0.85 9.9 0.2 3.2 3 0 0 3 3 3 0 Frog antimicrobial peptide Elicitin PF00964.12 AFZ80851.1 - 0.012 15.4 0.6 0.024 14.5 0.3 1.4 1 1 0 1 1 1 0 Elicitin GCV_T PF01571.16 AFZ80852.1 - 2e-09 37.1 0.0 7.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain LRR_4 PF12799.2 AFZ80853.1 - 1.2e-33 114.1 51.6 7.2e-08 31.8 3.5 6.2 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AFZ80853.1 - 3e-26 90.9 42.8 1.9e-09 37.1 5.0 4.6 3 2 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 AFZ80853.1 - 4.3e-16 56.4 42.3 0.32 11.1 0.1 10.2 10 0 0 10 10 10 9 Leucine Rich Repeat LRR_7 PF13504.1 AFZ80853.1 - 7.1e-10 37.4 31.4 0.71 10.3 0.2 10.2 10 1 1 11 11 11 4 Leucine rich repeat LRR_6 PF13516.1 AFZ80853.1 - 1.4e-06 27.7 39.2 5.8 7.2 0.0 10.2 8 2 3 11 11 11 5 Leucine Rich repeat LRR_9 PF14580.1 AFZ80853.1 - 3.7e-06 26.6 18.3 0.0001 21.9 2.5 3.4 1 1 2 3 3 3 3 Leucine-rich repeat FAINT PF04385.10 AFZ80854.1 - 6.8e-13 48.2 5.0 2.2e-06 27.3 0.7 3.9 4 0 0 4 4 4 3 Domain of unknown function, DUF529 MHCassoc_trimer PF08831.5 AFZ80855.1 - 0.058 13.2 2.0 0.3 10.9 0.3 2.4 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Imm29 PF15575.1 AFZ80855.1 - 0.081 12.5 0.1 0.56 9.7 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 29 AMP-binding PF00501.23 AFZ80856.1 - 6.7e-64 215.8 0.0 8.7e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AFZ80856.1 - 4.4e-05 24.3 0.1 9.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain hNIFK_binding PF12196.3 AFZ80858.1 - 0.036 13.4 0.4 0.065 12.6 0.2 1.4 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Nudc_N PF14050.1 AFZ80859.1 - 8.8e-14 51.2 0.0 1.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.11 AFZ80859.1 - 2.3e-13 50.4 0.0 4.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 CS domain DUF4404 PF14357.1 AFZ80859.1 - 0.26 11.7 1.1 0.52 10.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) tRNA-synt_1b PF00579.20 AFZ80860.1 - 2.3e-29 102.4 0.0 4e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-C2HC5 PF06221.8 AFZ80861.1 - 9.4e-15 54.1 6.6 1.5e-14 53.4 4.6 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DXP_synthase_N PF13292.1 AFZ80862.1 - 2.4e-83 279.1 0.0 1.7e-80 269.8 0.0 2.8 2 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.19 AFZ80862.1 - 9.7e-31 106.6 0.0 1.9e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AFZ80862.1 - 6.9e-19 67.9 0.0 1.4e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.16 AFZ80862.1 - 0.00036 19.4 0.1 0.12 11.1 0.0 2.3 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.16 AFZ80862.1 - 0.023 14.3 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 AFZ80862.1 - 0.06 12.0 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component Peptidase_M3 PF01432.15 AFZ80863.1 - 7.5e-52 176.8 0.0 1.1e-51 176.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF4344 PF14247.1 AFZ80863.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) Peptidase_M50B PF13398.1 AFZ80863.1 - 0.35 10.2 0.4 0.6 9.4 0.3 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Ank_2 PF12796.2 AFZ80864.1 - 1.9e-18 66.5 0.7 1.8e-12 47.3 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AFZ80864.1 - 1.9e-11 43.8 0.0 9.9e-05 22.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 AFZ80864.1 - 5.9e-11 41.6 0.3 2e-05 24.1 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 AFZ80864.1 - 2.7e-10 40.4 0.1 0.00011 22.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AFZ80864.1 - 4.5e-08 32.5 0.2 0.0053 16.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 AFZ80865.1 - 1.9e-34 117.8 0.4 1.5e-18 66.8 0.0 2.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 AFZ80865.1 - 2e-16 58.8 0.0 7.6e-08 31.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat TPR_11 PF13414.1 AFZ80865.1 - 1.8e-14 53.1 1.8 3.8e-10 39.2 0.0 2.6 1 1 1 2 2 2 2 TPR repeat Ank_3 PF13606.1 AFZ80865.1 - 2.8e-12 45.6 0.0 1.2e-05 25.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 AFZ80865.1 - 1e-10 41.5 0.0 1.5e-06 28.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 AFZ80865.1 - 9.3e-10 38.7 0.3 6.4e-07 29.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TPR_1 PF00515.23 AFZ80865.1 - 2e-06 27.1 0.0 0.26 10.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AFZ80865.1 - 2.7e-06 26.8 0.0 0.077 12.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AFZ80865.1 - 0.0061 17.0 0.0 0.7 10.6 0.0 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 AFZ80865.1 - 0.0084 16.2 0.4 0.37 11.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ80865.1 - 0.0098 15.6 0.2 7.5 6.5 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 AFZ80865.1 - 0.038 14.3 0.0 5.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 AFZ80865.1 - 0.06 13.2 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat tRNA_anti-codon PF01336.20 AFZ80865.1 - 0.11 12.3 0.1 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Phi-29_GP3 PF05435.6 AFZ80866.1 - 0.0029 16.8 0.2 0.0039 16.4 0.2 1.2 1 0 0 1 1 1 1 Phi-29 DNA terminal protein GP3 RrnaAD PF00398.15 AFZ80868.1 - 5.2e-24 84.6 0.1 6e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF605 PF04652.11 AFZ80869.1 - 0.011 15.1 8.4 0.018 14.4 5.8 1.2 1 0 0 1 1 1 0 Vta1 like DUF2255 PF10012.4 AFZ80869.1 - 0.026 14.5 0.8 4.8 7.1 0.0 3.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2255) RrnaAD PF00398.15 AFZ80870.1 - 1.8e-12 46.8 0.0 2.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 AFZ80870.1 - 6.9e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AFZ80870.1 - 0.00096 19.7 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AFZ80870.1 - 0.0038 17.6 0.2 0.019 15.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AFZ80870.1 - 0.0049 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AFZ80870.1 - 0.02 14.9 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 AFZ80870.1 - 0.048 12.5 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_31 PF13847.1 AFZ80870.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 AFZ80870.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase AP4E_app_platf PF14807.1 AFZ80871.1 - 0.077 13.2 0.3 0.45 10.7 0.1 2.5 2 1 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform WD40 PF00400.27 AFZ80873.1 - 7.4e-22 76.3 3.1 0.0011 18.7 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat TFIID_90kDa PF04494.10 AFZ80873.1 - 2.5e-07 30.8 0.9 4.4e-07 30.0 0.6 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Vps16_N PF04841.8 AFZ80873.1 - 0.00074 18.1 0.0 0.095 11.2 0.0 2.1 2 0 0 2 2 2 2 Vps16, N-terminal region Nup160 PF11715.3 AFZ80873.1 - 0.0076 14.4 0.0 0.012 13.7 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 GDI PF00996.13 AFZ80874.1 - 7.7e-40 136.5 0.0 6.6e-39 133.4 0.0 2.0 1 1 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 AFZ80874.1 - 0.00037 20.4 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AFZ80874.1 - 0.0077 15.1 0.0 0.099 11.5 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AFZ80874.1 - 0.2 10.4 0.0 0.47 9.2 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain DUF2731 PF10806.3 AFZ80876.1 - 0.0085 16.3 0.0 0.026 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) DUF1777 PF08648.7 AFZ80877.1 - 1.2e-25 90.2 64.8 3.5e-25 88.7 44.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) FAINT PF04385.10 AFZ80879.1 - 1.4e-08 34.4 6.1 0.051 13.4 0.1 4.3 5 1 0 5 5 5 3 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80881.1 - 6.4e-06 25.9 1.5 1e-05 25.2 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80881.1 - 0.036 13.5 2.0 0.049 13.1 1.4 1.1 1 0 0 1 1 1 0 Merozoite Antigen SNF2_N PF00176.18 AFZ80882.1 - 1.8e-52 177.9 0.8 4.7e-41 140.5 0.0 2.4 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 AFZ80882.1 - 2.5e-13 49.7 0.1 8.9e-12 44.7 0.0 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ80882.1 - 7e-08 32.5 2.0 2.2e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AFZ80882.1 - 7.6e-07 28.7 0.0 1.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.1 AFZ80882.1 - 0.02 14.5 10.1 0.12 11.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AIF_C PF14721.1 AFZ80882.1 - 2.7 8.2 6.2 39 4.4 3.3 2.8 2 1 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Cpn60_TCP1 PF00118.19 AFZ80883.1 - 2.6e-162 540.8 4.2 3.2e-162 540.5 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SKI PF01202.17 AFZ80883.1 - 0.025 14.4 0.1 0.059 13.2 0.1 1.6 1 0 0 1 1 1 0 Shikimate kinase ANAPC15 PF15243.1 AFZ80883.1 - 0.082 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 SAP PF02037.22 AFZ80885.1 - 0.078 12.5 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 SAP domain Glyco_hydro_4C PF11975.3 AFZ80885.1 - 0.32 10.7 4.1 0.55 9.9 2.8 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Hydrolase_3 PF08282.7 AFZ80888.1 - 3.9e-32 111.8 0.0 4.9e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AFZ80888.1 - 7.5e-07 28.6 0.0 0.0019 17.5 0.0 2.5 3 0 0 3 3 3 2 Sucrose-6F-phosphate phosphohydrolase Tubulin PF00091.20 AFZ80889.1 - 6.9e-11 42.3 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Orbi_NS3 PF01616.11 AFZ80889.1 - 0.033 13.1 0.3 7.6 5.4 0.0 2.3 2 0 0 2 2 2 0 Orbivirus NS3 Tubulin_C PF03953.12 AFZ80890.1 - 2e-51 173.2 0.2 5.3e-51 171.9 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin PF00091.20 AFZ80890.1 - 5.5e-51 173.4 0.0 8.1e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DUF4253 PF14062.1 AFZ80890.1 - 0.024 14.2 0.0 0.38 10.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) Tubulin_3 PF14881.1 AFZ80890.1 - 0.031 13.7 0.0 0.087 12.2 0.0 1.8 2 0 0 2 2 2 0 Tubulin domain Ribosomal_L32e PF01655.13 AFZ80891.1 - 1.4e-44 150.6 4.0 1.7e-44 150.3 2.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Endonuclease_NS PF01223.18 AFZ80891.1 - 0.009 15.6 0.1 0.0098 15.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DEAD PF00270.24 AFZ80891.1 - 0.028 13.9 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase RabGAP-TBC PF00566.13 AFZ80895.1 - 3.1e-21 75.8 0.1 3.1e-21 75.8 0.0 1.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain FAINT PF04385.10 AFZ80896.1 - 6.3e-06 25.9 1.7 1.4e-05 24.8 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function, DUF529 Adaptin_N PF01602.15 AFZ80897.1 - 2.1e-54 184.7 17.0 2.6e-54 184.4 11.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 AFZ80897.1 - 1e-08 35.2 11.9 2.5e-05 24.2 1.2 3.5 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 AFZ80897.1 - 1.7e-07 31.4 0.1 0.0024 18.1 0.0 3.8 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.17 AFZ80897.1 - 2e-07 30.4 1.1 0.0061 16.5 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat RasGEF_N_2 PF14663.1 AFZ80897.1 - 2e-05 24.4 4.6 0.0081 16.0 0.0 3.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Vac14_Fab1_bd PF12755.2 AFZ80897.1 - 0.00041 20.6 2.6 0.16 12.3 0.0 3.5 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 AFZ80897.1 - 0.011 15.1 0.6 0.083 12.2 0.0 2.5 2 1 0 2 2 2 0 CLASP N terminal SPC22 PF04573.7 AFZ80900.1 - 3.4e-27 94.7 0.1 7e-27 93.7 0.1 1.5 1 0 0 1 1 1 1 Signal peptidase subunit Prefoldin_2 PF01920.15 AFZ80901.1 - 1e-13 50.9 7.4 1.2e-13 50.6 5.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Apolipoprotein PF01442.13 AFZ80901.1 - 0.052 13.0 2.9 0.078 12.4 0.3 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Bap31 PF05529.7 AFZ80901.1 - 0.054 12.9 3.0 0.068 12.6 2.1 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3940 PF13076.1 AFZ80901.1 - 0.054 13.0 0.5 0.098 12.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) Sec20 PF03908.8 AFZ80901.1 - 0.17 11.5 1.1 0.72 9.5 0.3 1.9 1 1 1 2 2 2 0 Sec20 Spc24 PF08286.6 AFZ80901.1 - 0.25 11.0 4.7 0.16 11.6 0.3 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin PF02996.12 AFZ80901.1 - 0.26 10.9 5.6 0.99 9.0 0.7 2.2 2 0 0 2 2 2 0 Prefoldin subunit bZIP_Maf PF03131.12 AFZ80901.1 - 0.6 10.4 5.2 8.3 6.7 0.5 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor Sds3 PF08598.6 AFZ80901.1 - 1.4 8.3 6.6 0.8 9.1 2.1 1.7 1 1 0 1 1 1 0 Sds3-like bZIP_1 PF00170.16 AFZ80901.1 - 8.5 6.4 10.1 1.4 8.8 3.6 1.9 2 0 0 2 2 2 0 bZIP transcription factor Bac_DNA_binding PF00216.16 AFZ80902.1 - 4.7e-20 71.4 0.6 6.3e-20 70.9 0.4 1.2 1 0 0 1 1 1 1 Bacterial DNA-binding protein DUF4496 PF14908.1 AFZ80902.1 - 0.016 15.0 0.4 0.029 14.2 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4496) Proteasom_PSMB PF10508.4 AFZ80902.1 - 0.063 11.5 0.0 0.073 11.3 0.0 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Cut12 PF11500.3 AFZ80903.1 - 0.019 14.6 2.7 0.036 13.7 1.8 1.5 1 0 0 1 1 1 0 Spindle pole body formation-associated protein FAINT PF04385.10 AFZ80904.1 - 6.4e-14 51.5 3.7 0.0013 18.5 0.4 3.6 3 0 0 3 3 3 3 Domain of unknown function, DUF529 VPS9 PF02204.13 AFZ80905.1 - 0.0013 18.7 0.0 0.0069 16.3 0.0 2.3 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Activator-TraM PF11657.3 AFZ80905.1 - 0.0079 15.6 0.0 0.018 14.4 0.0 1.7 1 1 0 1 1 1 1 Transcriptional activator TraM CTP_transf_2 PF01467.21 AFZ80906.1 - 0.00032 20.7 0.0 0.00059 19.9 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 AFZ80906.1 - 0.093 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase zf-A20 PF01754.11 AFZ80907.1 - 6.7e-12 44.7 10.2 6.7e-12 44.7 7.1 2.5 3 0 0 3 3 3 1 A20-like zinc finger zf-AN1 PF01428.11 AFZ80907.1 - 1.5e-10 40.7 6.1 1.5e-10 40.7 4.2 2.5 2 1 1 3 3 3 1 AN1-like Zinc finger NdhO PF11910.3 AFZ80908.1 - 0.0032 17.0 0.0 0.0091 15.6 0.0 1.8 1 0 0 1 1 1 1 Cyanobacterial and plant NDH-1 subunit O WD40 PF00400.27 AFZ80909.1 - 1.3e-18 66.0 1.3 2.1e-05 24.2 0.0 4.3 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 AFZ80909.1 - 0.06 11.4 0.4 0.72 7.9 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 WD40 PF00400.27 AFZ80910.1 - 8.9e-07 28.5 7.1 0.12 12.2 0.0 5.4 4 1 0 4 4 4 3 WD domain, G-beta repeat zf-RING_2 PF13639.1 AFZ80911.1 - 2.3e-11 43.3 9.8 7e-11 41.7 6.8 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AFZ80911.1 - 1.4e-07 31.0 5.6 3e-07 29.9 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AFZ80911.1 - 4.8e-07 29.4 6.7 1e-06 28.3 4.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 AFZ80911.1 - 1.1e-05 25.3 7.9 3.6e-05 23.7 5.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AFZ80911.1 - 0.00012 21.9 9.5 0.00012 21.9 6.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AFZ80911.1 - 0.00014 21.4 9.1 0.00033 20.2 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 AFZ80911.1 - 0.025 14.3 2.2 0.073 12.8 1.5 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 AFZ80911.1 - 0.046 13.5 1.9 0.13 12.1 1.3 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 AFZ80911.1 - 0.39 10.3 7.3 1 8.9 5.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 AFZ80911.1 - 9.5 6.2 11.4 64 3.6 7.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain LURAP PF14854.1 AFZ80912.1 - 0.024 14.3 0.2 0.031 13.9 0.1 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein HTH_19 PF12844.2 AFZ80912.1 - 0.097 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0160 PF03690.8 AFZ80912.1 - 0.097 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) DUF2254 PF10011.4 AFZ80913.1 - 0.33 9.3 2.7 0.69 8.3 1.9 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF3311 PF11755.3 AFZ80913.1 - 8.2 6.0 11.7 1 8.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) FAINT PF04385.10 AFZ80915.1 - 9.8e-18 63.7 4.1 9.2e-08 31.8 0.8 3.7 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 AFZ80915.1 - 1.3e-12 48.1 0.0 2.4e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ80915.1 - 6.6e-09 35.6 0.0 1.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ80915.1 - 1.1e-08 34.7 0.2 9.9e-08 31.7 0.1 2.6 2 0 0 2 2 2 1 Putative lysophospholipase EMA PF02488.10 AFZ80915.1 - 0.00024 20.6 0.8 0.4 10.1 0.1 3.3 2 1 1 3 3 3 2 Merozoite Antigen Abhydrolase_1 PF00561.15 AFZ80915.1 - 0.015 14.9 0.0 0.046 13.2 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold UPF0565 PF10561.4 AFZ80915.1 - 0.015 14.2 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Abhydrolase_3 PF07859.8 AFZ80915.1 - 0.048 13.2 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 AFZ80915.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Pkinase PF00069.20 AFZ80916.1 - 1.3e-60 204.7 0.2 2.8e-60 203.6 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ80916.1 - 5.7e-29 100.9 0.0 7e-19 67.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 AFZ80916.1 - 4.1e-05 22.7 0.0 7.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AFZ80916.1 - 0.043 12.7 0.0 1.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 AFZ80916.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2392 PF10288.4 AFZ80917.1 - 7.6e-08 32.6 0.0 1.8e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) UCH PF00443.24 AFZ80918.1 - 3.1e-24 85.5 0.2 7.2e-24 84.3 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 AFZ80918.1 - 1.8e-11 43.9 0.0 1.1e-10 41.4 0.0 2.4 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 AFZ80918.1 - 0.00022 20.7 0.1 0.0087 15.5 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF2457 PF10446.4 AFZ80919.1 - 0.29 9.8 22.3 0.39 9.4 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Drc1-Sld2 PF11719.3 AFZ80919.1 - 3.3 6.7 13.5 4.3 6.3 9.4 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Utp14 PF04615.8 AFZ80919.1 - 9.1 4.2 21.3 10 4.1 14.8 1.0 1 0 0 1 1 1 0 Utp14 protein Ribosomal_L1 PF00687.16 AFZ80920.1 - 2.6e-46 157.7 3.0 3.2e-46 157.4 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family BH3 PF15285.1 AFZ80921.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting SSrecog PF03531.9 AFZ80922.1 - 3.6e-50 170.3 0.4 1.8e-49 168.1 0.1 2.1 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 AFZ80922.1 - 5.1e-25 87.2 0.2 1e-24 86.2 0.1 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like LCM PF04072.9 AFZ80923.1 - 2.7e-18 66.1 0.0 5.1e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DED PF01335.16 AFZ80923.1 - 0.063 13.3 0.9 0.2 11.7 0.2 2.1 2 0 0 2 2 2 0 Death effector domain Transketolase_N PF00456.16 AFZ80923.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain PUF PF00806.14 AFZ80924.1 - 4.2e-15 54.2 11.2 1.3e-06 27.5 0.2 7.1 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat Cnl2_NKP2 PF09447.5 AFZ80924.1 - 0.15 11.7 1.4 0.95 9.1 0.0 2.4 2 0 0 2 2 2 0 Cnl2/NKP2 family protein DUF2637 PF10935.3 AFZ80925.1 - 0.84 9.5 11.7 1.5e+02 2.2 8.1 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2637) Synaptobrevin PF00957.16 AFZ80925.1 - 3.6 7.2 6.3 12 5.6 4.3 1.8 1 0 0 1 1 1 0 Synaptobrevin Abhydrolase_6 PF12697.2 AFZ80926.1 - 2.8e-06 27.3 0.0 2.1e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AFZ80926.1 - 0.00037 20.1 0.0 0.0007 19.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 AFZ80926.1 - 0.2 10.0 0.0 0.36 9.2 0.0 1.3 1 0 0 1 1 1 0 Ndr family FAINT PF04385.10 AFZ80927.1 - 2.4e-10 40.0 0.0 5.3e-06 26.1 0.0 3.2 2 1 0 2 2 2 2 Domain of unknown function, DUF529 CBM_25 PF03423.8 AFZ80927.1 - 0.012 15.7 0.3 0.042 13.9 0.0 2.0 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Viral_P18 PF04521.8 AFZ80927.1 - 0.031 13.7 1.5 2.2 7.7 1.1 2.5 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF3775 PF12616.3 AFZ80927.1 - 0.051 13.3 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) M16C_assoc PF08367.6 AFZ80927.1 - 0.62 8.8 4.8 0.99 8.1 3.3 1.3 1 0 0 1 1 1 0 Peptidase M16C associated DUF106 PF01956.11 AFZ80927.1 - 1.5 8.3 3.5 4.2 6.8 2.4 1.8 1 1 0 1 1 1 0 Integral membrane protein DUF106 Pkinase PF00069.20 AFZ80929.1 - 1.4e-48 165.3 0.0 2e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ80929.1 - 3.9e-33 114.6 0.0 5.8e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AFZ80929.1 - 0.0013 17.7 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AFZ80929.1 - 0.022 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TF_Zn_Ribbon PF08271.7 AFZ80929.1 - 0.077 12.3 0.4 0.29 10.4 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding APH PF01636.18 AFZ80929.1 - 0.1 12.2 0.0 2.5 7.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family C2 PF00168.25 AFZ80930.1 - 9.9e-06 25.3 0.0 0.0016 18.2 0.0 2.9 2 0 0 2 2 2 2 C2 domain GIDA PF01134.17 AFZ80931.1 - 6.9e-138 459.7 0.0 9.1e-138 459.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 AFZ80931.1 - 5.3e-09 35.6 0.6 1.1e-08 34.6 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA_assoc_3 PF13932.1 AFZ80931.1 - 4.2e-07 29.9 0.0 1.3e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 AFZ80931.1 - 3.4e-06 27.0 2.2 9.3e-06 25.6 1.5 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AFZ80931.1 - 8.9e-06 24.7 1.3 0.003 16.4 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 AFZ80931.1 - 0.0001 21.3 1.9 0.21 10.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 AFZ80931.1 - 0.00027 21.2 0.3 0.001 19.4 0.2 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AFZ80931.1 - 0.007 14.8 3.6 0.41 9.0 0.6 2.9 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.1 AFZ80931.1 - 0.021 14.9 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HHH PF00633.18 AFZ80931.1 - 0.032 13.9 0.0 0.094 12.4 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Lycopene_cycl PF05834.7 AFZ80931.1 - 0.034 13.0 0.7 0.83 8.4 0.2 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 AFZ80931.1 - 0.13 11.2 2.0 0.52 9.3 1.4 1.9 1 1 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 AFZ80931.1 - 0.76 8.3 3.1 2.2 6.7 0.4 2.0 2 0 0 2 2 2 0 Tryptophan halogenase SUI1 PF01253.17 AFZ80932.1 - 1.6e-27 95.0 0.5 2.1e-27 94.7 0.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Snf7 PF03357.16 AFZ80933.1 - 8.5e-23 80.5 22.6 1.3e-22 79.9 15.6 1.3 1 1 0 1 1 1 1 Snf7 Exonuc_VII_S PF02609.11 AFZ80933.1 - 0.014 15.1 3.1 0.9 9.3 0.1 3.7 3 0 0 3 3 3 0 Exonuclease VII small subunit DivIC PF04977.10 AFZ80933.1 - 0.034 13.6 1.8 0.034 13.6 1.2 3.5 3 1 1 4 4 4 0 Septum formation initiator Ub-Mut7C PF14451.1 AFZ80933.1 - 0.045 13.2 0.0 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 Mut7-C ubiquitin DUF4635 PF15466.1 AFZ80933.1 - 0.62 9.3 6.1 10 5.4 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4635) SlyX PF04102.7 AFZ80933.1 - 0.89 9.9 11.0 2.4 8.6 0.1 3.5 3 1 0 3 3 3 0 SlyX NPV_P10 PF05531.7 AFZ80933.1 - 0.91 9.8 9.8 35 4.7 0.2 3.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Pol_alpha_B_N PF08418.5 AFZ80933.1 - 1.4 8.4 11.6 0.018 14.5 1.5 2.0 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal Snapin_Pallidin PF14712.1 AFZ80933.1 - 1.6 9.0 13.8 0.46 10.8 0.9 3.0 1 1 0 2 2 2 0 Snapin/Pallidin eIF3_N PF09440.5 AFZ80933.1 - 4.3 7.5 16.1 1.2 9.2 2.7 2.3 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Tom37_C PF11801.3 AFZ80933.1 - 6.6 6.5 14.3 1.3 8.9 1.8 2.1 2 0 0 2 2 2 0 Tom37 C-terminal domain V-SNARE PF05008.10 AFZ80933.1 - 9.3 6.5 14.2 0.61 10.2 0.9 3.2 2 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF1899 PF08953.6 AFZ80934.1 - 0.017 14.7 0.0 4.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) FAINT PF04385.10 AFZ80935.1 - 0.00013 21.7 0.2 0.00025 20.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80936.1 - 2e-07 30.7 6.4 0.00035 20.3 1.1 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80936.1 - 1.4e-05 24.7 6.1 0.024 14.1 0.1 2.2 1 1 1 2 2 2 2 Merozoite Antigen FAINT PF04385.10 AFZ80937.1 - 8.6e-16 57.5 3.3 1.7e-06 27.7 0.3 4.8 4 0 0 4 4 4 3 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80937.1 - 1.8e-05 24.3 8.5 0.003 17.0 5.3 2.8 1 1 1 2 2 2 2 Merozoite Antigen Thioredoxin_8 PF13905.1 AFZ80937.1 - 0.11 12.5 2.3 20 5.3 0.0 3.3 3 0 0 3 3 3 0 Thioredoxin-like FAINT PF04385.10 AFZ80941.1 - 8e-10 38.4 7.1 1.3e-07 31.3 0.5 3.2 3 1 0 3 3 3 2 Domain of unknown function, DUF529 Nop14 PF04147.7 AFZ80941.1 - 4.6 5.0 9.9 6.1 4.6 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_M17 PF00883.16 AFZ80942.1 - 1.8e-108 362.1 0.2 2.2e-108 361.8 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain FAINT PF04385.10 AFZ80943.1 - 3.5e-26 90.8 14.0 4.2e-09 36.1 0.2 5.3 4 2 0 4 4 4 4 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80944.1 - 3e-10 39.7 1.0 0.00051 19.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 AnfO_nitrog PF09582.5 AFZ80946.1 - 0.012 14.7 3.2 0.78 8.8 0.0 2.5 2 1 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) IZUMO PF15005.1 AFZ80946.1 - 0.077 13.0 2.8 0.6 10.1 0.2 2.2 2 0 0 2 2 2 0 Izumo sperm-egg fusion HXXSHH PF07586.6 AFZ80946.1 - 0.086 11.7 0.1 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) APG6 PF04111.7 AFZ80946.1 - 0.45 9.4 6.7 0.75 8.7 4.6 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 OAD_gamma PF04277.8 AFZ80946.1 - 9.2 6.7 8.9 2.2 8.6 0.4 3.1 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DeoC PF01791.4 AFZ80947.1 - 0.078 12.2 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase XPG_I PF00867.13 AFZ80951.1 - 1.7e-26 92.0 0.0 5.8e-26 90.3 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 AFZ80951.1 - 0.00011 21.8 0.0 0.00028 20.4 0.0 1.7 1 0 0 1 1 1 1 XPG domain containing BRCT PF00533.21 AFZ80951.1 - 0.068 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain 5_3_exonuc PF01367.15 AFZ80951.1 - 0.079 13.1 0.2 0.48 10.6 0.0 2.4 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold XPG_N PF00752.12 AFZ80953.1 - 0.00098 19.3 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 XPG N-terminal domain DUF2997 PF11211.3 AFZ80953.1 - 0.0082 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2997) FAINT PF04385.10 AFZ80954.1 - 1.2e-28 98.7 14.0 5.4e-05 22.9 0.0 7.7 7 0 0 7 7 7 7 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80954.1 - 7.3e-18 64.9 19.2 0.0025 17.3 0.0 6.6 4 2 2 6 6 6 6 Merozoite Antigen NUFIP1 PF10453.4 AFZ80955.1 - 2.4e-05 23.7 1.9 2.4e-05 23.7 1.3 1.8 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH_2 PF14608.1 AFZ80955.1 - 0.042 13.8 1.6 0.18 11.8 1.1 2.2 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type BIR PF00653.16 AFZ80955.1 - 0.089 13.2 1.5 0.24 11.8 1.1 1.7 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain zf-CCCH PF00642.19 AFZ80955.1 - 0.82 9.4 6.3 0.15 11.8 1.5 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-H2C2_2 PF13465.1 AFZ80955.1 - 8.6 6.8 7.4 15 6.1 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain LANC_like PF05147.8 AFZ80956.1 - 0.028 13.0 0.1 0.057 11.9 0.0 1.5 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein PspC PF04024.7 AFZ80956.1 - 0.075 12.5 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 PspC domain FAINT PF04385.10 AFZ80957.1 - 0.078 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, DUF529 VSP PF03302.8 AFZ80961.1 - 0.01 14.4 0.1 0.026 13.1 0.1 1.6 1 0 0 1 1 1 0 Giardia variant-specific surface protein ProRS-C_2 PF09181.5 AFZ80961.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal AWPM-19 PF05512.6 AFZ80962.1 - 0.11 12.5 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 AWPM-19-like family Choline_kinase PF01633.15 AFZ80963.1 - 1.7e-28 99.6 0.0 2.5e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 AFZ80963.1 - 1.8e-10 40.9 0.0 2.1e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.27 AFZ80964.1 - 1.3e-10 40.6 1.1 7.3e-08 32.0 0.0 2.5 3 1 0 3 3 3 2 WD domain, G-beta repeat WD40 PF00400.27 AFZ80966.1 - 3.1e-33 112.4 0.5 5.1e-10 38.8 0.0 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 AFZ80966.1 - 0.0025 16.0 0.1 0.051 11.7 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 FAINT PF04385.10 AFZ80967.1 - 1.5e-11 43.9 0.0 0.0062 16.3 0.0 3.3 3 0 0 3 3 3 3 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ80968.1 - 2.8e-05 23.8 0.6 0.26 11.1 0.3 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80968.1 - 0.0072 15.8 3.6 0.07 12.6 0.2 3.1 2 1 1 4 4 4 1 Merozoite Antigen Frataxin_Cyay PF01491.11 AFZ80968.1 - 0.038 13.8 0.9 0.098 12.4 0.0 2.1 2 1 0 2 2 2 0 Frataxin-like domain Imm34 PF15596.1 AFZ80969.1 - 0.027 14.6 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 34 KH_1 PF00013.24 AFZ80969.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 KH domain KH_3 PF13014.1 AFZ80969.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.8 1 1 0 1 1 1 0 KH domain MSA-2c PF12238.3 AFZ80970.1 - 0.2 11.3 2.0 0.35 10.4 1.4 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c AAA PF00004.24 AFZ80972.1 - 4.3e-42 143.4 0.0 8.4e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AFZ80972.1 - 1.4e-07 31.6 0.0 2.3e-06 27.7 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 AFZ80972.1 - 1.9e-06 27.8 0.2 3.4e-05 23.8 0.0 2.5 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 AFZ80972.1 - 3.8e-06 26.6 0.0 7.7e-05 22.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AFZ80972.1 - 1.4e-05 25.2 0.2 0.0013 18.9 0.0 2.7 2 1 1 3 3 2 1 AAA domain RuvB_N PF05496.7 AFZ80972.1 - 1.6e-05 24.1 0.0 3.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 AFZ80972.1 - 0.00012 22.9 0.1 0.00034 21.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AFZ80972.1 - 0.00045 19.6 0.2 0.0025 17.2 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 AFZ80972.1 - 0.0011 19.2 0.0 0.0038 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 AFZ80972.1 - 0.0012 19.0 0.0 0.0026 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.8 AFZ80972.1 - 0.0013 17.6 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 AFZ80972.1 - 0.0023 17.8 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 AFZ80972.1 - 0.0026 16.5 0.0 0.0053 15.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 AFZ80972.1 - 0.0027 17.4 0.1 0.0072 16.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 AFZ80972.1 - 0.004 17.1 0.0 0.0093 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AFZ80972.1 - 0.0044 16.1 0.0 0.0089 15.2 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 AFZ80972.1 - 0.0064 15.9 0.1 0.027 13.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 AFZ80972.1 - 0.0065 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AFZ80972.1 - 0.0069 16.0 0.1 0.057 13.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 AFZ80972.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 AFZ80972.1 - 0.015 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 AFZ80972.1 - 0.019 14.4 0.0 0.085 12.3 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 AFZ80972.1 - 0.029 13.4 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Med4 PF10018.4 AFZ80972.1 - 0.03 13.7 0.4 0.13 11.6 0.1 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4200 PF13863.1 AFZ80972.1 - 0.038 13.9 5.3 0.034 14.0 2.5 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) Sigma54_activ_2 PF14532.1 AFZ80972.1 - 0.044 13.8 0.1 0.2 11.7 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 AFZ80972.1 - 0.056 12.3 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 AFZ80972.1 - 0.059 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein BLOC1_2 PF10046.4 AFZ80972.1 - 0.06 13.4 0.5 0.19 11.8 0.2 1.9 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KaiC PF06745.8 AFZ80972.1 - 0.079 12.0 0.0 0.22 10.6 0.0 1.8 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.1 AFZ80972.1 - 0.087 12.3 0.0 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 AFZ80972.1 - 0.095 12.9 0.0 0.5 10.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter UPF0079 PF02367.12 AFZ80972.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DivIC PF04977.10 AFZ80972.1 - 0.39 10.2 3.9 1.7 8.1 1.7 2.6 3 0 0 3 3 3 0 Septum formation initiator DUF4280 PF14107.1 AFZ80973.1 - 0.014 15.7 0.2 0.049 13.9 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4280) HEAT PF02985.17 AFZ80974.1 - 3.6e-10 39.0 2.3 0.001 18.9 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 AFZ80974.1 - 5.9e-10 39.3 1.7 0.06 13.6 0.0 7.1 7 0 0 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 AFZ80974.1 - 0.00049 20.5 8.1 2.3 8.8 0.0 7.1 8 0 0 8 8 8 2 HEAT-like repeat FAINT PF04385.10 AFZ80975.1 - 4.2e-15 55.3 0.1 3.1e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 MORN_2 PF07661.8 AFZ80975.1 - 0.095 12.7 0.2 0.67 10.1 0.0 2.6 2 0 0 2 2 2 0 MORN repeat variant Imm35 PF15581.1 AFZ80977.1 - 0.011 15.7 0.1 0.023 14.6 0.0 1.5 1 1 0 1 1 1 0 Immunity protein 35 DUF4199 PF13858.1 AFZ80978.1 - 0.03 14.2 1.1 0.05 13.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) TF_Zn_Ribbon PF08271.7 AFZ80978.1 - 0.24 10.7 1.5 0.52 9.6 1.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Syndecan PF01034.15 AFZ80978.1 - 0.38 10.4 6.8 1.4 8.6 4.5 2.1 1 1 1 2 2 2 0 Syndecan domain Podoplanin PF05808.6 AFZ80978.1 - 0.39 10.2 3.0 12 5.4 0.1 3.3 3 0 0 3 3 3 0 Podoplanin FAINT PF04385.10 AFZ80979.1 - 9.6e-06 25.3 0.0 0.0085 15.9 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ80979.1 - 0.0032 16.9 0.4 1.7 8.0 0.0 2.2 2 0 0 2 2 2 2 Merozoite Antigen DUF1899 PF08953.6 AFZ80980.1 - 0.043 13.4 0.2 0.13 11.9 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) Got1 PF04178.7 AFZ80981.1 - 1.1e-13 51.3 10.9 1.3e-13 51.0 7.5 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1510 PF07423.6 AFZ80985.1 - 0.081 12.2 9.6 0.1 11.9 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 AFZ80985.1 - 0.26 10.4 3.1 0.33 10.0 2.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain NOA36 PF06524.7 AFZ80985.1 - 0.85 8.8 7.4 1.1 8.4 5.1 1.1 1 0 0 1 1 1 0 NOA36 protein Trypan_PARP PF05887.6 AFZ80985.1 - 1.7 8.4 11.4 3 7.6 7.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.7 AFZ80985.1 - 2.9 5.6 14.0 3.5 5.4 9.7 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 AFZ80985.1 - 3.4 6.0 13.2 4.2 5.7 9.1 1.1 1 0 0 1 1 1 0 Daxx Family DASH_Dad1 PF08649.5 AFZ80986.1 - 0.49 10.1 5.1 0.87 9.3 0.7 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad1 FAINT PF04385.10 AFZ80987.1 - 2.9e-05 23.8 0.6 6.5e-05 22.7 0.2 1.8 1 1 1 2 2 2 1 Domain of unknown function, DUF529 Cyd_oper_YbgE PF09600.5 AFZ80989.1 - 0.19 11.8 0.6 7.6 6.7 0.2 2.0 1 1 1 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) INCENP_ARK-bind PF03941.10 AFZ80991.1 - 4.3e-05 23.2 1.9 8.1e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region RBFA PF02033.13 AFZ80993.1 - 7.7e-07 29.1 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Ribosome-binding factor A FAINT PF04385.10 AFZ80994.1 - 1.4e-36 124.1 36.1 5.2e-06 26.2 1.8 9.6 8 1 1 9 9 9 8 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 AFZ80995.1 - 2.4e-15 57.0 0.0 6e-15 55.7 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ80995.1 - 2e-11 43.8 0.0 8.7e-11 41.7 0.0 2.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family FAINT PF04385.10 AFZ80995.1 - 1.4e-10 40.8 11.1 0.0019 18.0 0.0 5.3 5 1 0 5 5 5 3 Domain of unknown function, DUF529 Hydrolase_4 PF12146.3 AFZ80995.1 - 1.2e-09 37.8 0.5 2.6e-08 33.6 0.1 2.9 3 0 0 3 3 3 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 AFZ80995.1 - 0.0022 17.6 0.2 0.93 9.0 0.0 2.9 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 AFZ80995.1 - 0.0055 16.1 0.0 2.9 7.2 0.0 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 AFZ80995.1 - 0.027 14.3 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DUF676 PF05057.9 AFZ80995.1 - 0.029 13.6 0.0 0.065 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 AFZ80995.1 - 0.031 13.8 0.0 0.17 11.4 0.0 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF2305 PF10230.4 AFZ80995.1 - 0.066 12.6 0.2 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Gin PF10764.4 AFZ80997.1 - 0.26 11.0 1.9 0.38 10.4 0.1 2.3 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin BRCT PF00533.21 AFZ80998.1 - 1e-10 41.6 0.8 5.4e-08 32.8 0.1 2.8 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Phage_Orf51 PF06194.6 AFZ80998.1 - 0.045 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Phage Conserved Open Reading Frame 51 MMR_HSR1 PF01926.18 AFZ81001.1 - 1.9e-13 50.3 0.0 2.4e-12 46.8 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AFZ81001.1 - 1.4e-05 24.4 0.0 4.7e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 AFZ81001.1 - 0.00027 20.1 0.0 0.0014 17.7 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 AFZ81001.1 - 0.0025 17.6 0.0 0.28 10.9 0.0 3.0 2 2 1 3 3 3 1 Dynamin family Arch_ATPase PF01637.13 AFZ81001.1 - 0.087 12.5 0.3 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase DUF2407_C PF13373.1 AFZ81002.1 - 0.15 11.9 0.0 0.5 10.2 0.0 1.8 2 0 0 2 2 2 0 DUF2407 C-terminal domain FAINT PF04385.10 AFZ81005.1 - 1.2e-17 63.5 1.1 3.4e-08 33.2 0.0 3.8 3 2 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 AFZ81005.1 - 2.3e-09 37.1 8.3 1.1e-05 25.0 3.6 3.4 1 1 1 2 2 2 2 Merozoite Antigen FAINT PF04385.10 AFZ81006.1 - 6.9e-12 45.0 7.1 4.9e-07 29.4 1.3 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 AFZ81006.1 - 9.1e-06 25.3 6.9 0.002 17.6 0.4 2.3 1 1 1 2 2 2 2 Merozoite Antigen FAINT PF04385.10 AFZ81007.1 - 3e-18 65.4 3.1 4.2e-06 26.5 0.0 3.6 3 1 0 3 3 3 3 Domain of unknown function, DUF529 DUF3770 PF12603.3 AFZ81007.1 - 0.031 13.3 0.5 0.049 12.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) TP53IP5 PF15331.1 AFZ81008.1 - 5.4 6.8 4.9 9.9 5.9 3.4 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Acetyltransf_1 PF00583.19 AFZ81009.1 - 0.00047 20.1 0.0 0.00066 19.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ribosomal_S10 PF00338.17 AFZ81010.1 - 6.1e-32 109.3 0.1 7e-32 109.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e IMCp PF12314.3 AFZ81011.1 - 2.7e-29 101.1 35.5 2.7e-29 101.1 24.6 2.6 2 1 1 3 3 3 2 Inner membrane complex protein FAINT PF04385.10 AFZ81012.1 - 3.8e-05 23.4 0.1 6.9e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ81013.1 - 4.7e-06 26.3 0.1 6.7e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ81014.1 - 1.1e-29 102.0 6.6 3e-06 26.9 0.2 6.8 6 1 0 6 6 6 6 Domain of unknown function, DUF529 DUF2457 PF10446.4 AFZ81014.1 - 0.039 12.7 0.1 0.057 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MKT1_C PF12246.3 AFZ81015.1 - 4.2e-35 120.8 0.0 6.2e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 AFZ81015.1 - 5e-20 71.6 0.0 1.5e-19 70.1 0.0 1.9 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 AFZ81015.1 - 2.8e-10 40.1 0.0 6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 AFZ81015.1 - 4.7e-05 23.5 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain PLD_C PF12357.3 AFZ81015.1 - 0.03 13.8 0.0 0.12 11.9 0.0 2.0 1 0 0 1 1 1 0 Phospholipase D C terminal DUF3288 PF11691.3 AFZ81015.1 - 0.24 11.1 1.1 23 4.7 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3288) GTP_EFTU PF00009.22 AFZ81019.1 - 3.8e-37 127.5 0.0 5.5e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 AFZ81019.1 - 1.2e-20 73.1 0.0 6e-20 70.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_IV PF03764.13 AFZ81019.1 - 8.5e-20 70.5 0.0 2.1e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 AFZ81019.1 - 2.3e-08 34.0 0.0 5.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 AFZ81019.1 - 1.7e-07 30.9 0.0 3.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 AFZ81019.1 - 5.3e-05 23.1 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AFZ81019.1 - 0.013 15.9 0.0 0.11 13.0 0.0 2.4 1 1 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 AFZ81019.1 - 0.068 12.3 0.0 4.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Laminin_G_3 PF13385.1 AFZ81020.1 - 7.2e-15 55.5 0.0 1e-14 55.1 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 AFZ81020.1 - 1.2e-08 35.0 0.0 3.2e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.18 AFZ81020.1 - 4.2e-06 26.7 0.0 1.2e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Laminin G domain FAINT PF04385.10 AFZ81021.1 - 1.3e-06 28.1 3.7 0.017 14.9 0.3 3.6 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 AFZ81021.1 - 0.012 15.0 0.4 0.067 12.6 0.1 2.0 2 0 0 2 2 2 0 Merozoite Antigen AvrL567-A PF11529.3 AFZ81023.1 - 0.054 13.4 0.0 0.06 13.3 0.0 1.1 1 0 0 1 1 1 0 Melampsora lini avirulence protein AvrL567-A OmpH PF03938.9 AFZ81023.1 - 0.088 12.7 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CLP_protease PF00574.18 AFZ81024.1 - 6.8e-69 231.1 0.0 7.9e-69 230.9 0.0 1.0 1 0 0 1 1 1 1 Clp protease DUF496 PF04363.7 AFZ81024.1 - 0.09 12.5 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF496) DUF4223 PF13978.1 AFZ81024.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) HSP20 PF00011.16 AFZ81025.1 - 8.2e-12 44.8 0.0 1.1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family RE_SinI PF09570.5 AFZ81030.1 - 0.072 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 SinI restriction endonuclease FAINT PF04385.10 AFZ81031.1 - 7.7e-10 38.4 0.0 7.4e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 AFZ81032.1 - 0.00087 19.0 2.1 0.0034 17.2 0.3 2.4 1 1 1 2 2 2 1 Domain of unknown function, DUF529 EMA PF02488.10 AFZ81032.1 - 0.0099 15.3 0.1 0.013 14.9 0.1 1.1 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 AFZ81033.1 - 2.4e-20 72.1 5.7 4.2e-07 29.7 0.0 5.2 5 0 0 5 5 5 4 Domain of unknown function, DUF529 EMA PF02488.10 AFZ81033.1 - 2.8e-05 23.7 0.0 0.18 11.2 0.1 2.4 2 0 0 2 2 2 2 Merozoite Antigen Peptidase_C48 PF02902.14 AFZ81034.1 - 1.5e-31 109.6 1.8 1.5e-31 109.6 1.2 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain AAA_2 PF07724.9 AFZ81035.1 - 5.6e-56 189.1 0.0 1.1e-52 178.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 AFZ81035.1 - 2.9e-25 87.9 0.1 1.7e-24 85.4 0.0 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 AFZ81035.1 - 8.6e-25 87.4 0.0 7.4e-13 48.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.15 AFZ81035.1 - 2.4e-21 75.4 0.1 4.2e-14 52.1 0.0 2.8 2 0 0 2 2 2 2 Clp amino terminal domain AAA_5 PF07728.9 AFZ81035.1 - 1.1e-16 60.7 0.1 1.1e-11 44.6 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AFZ81035.1 - 2.3e-09 37.2 0.2 0.0026 17.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 AFZ81035.1 - 4.1e-09 36.6 7.5 0.00029 20.8 0.0 5.1 4 2 1 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.21 AFZ81035.1 - 1.1e-08 34.7 0.0 2.6e-06 27.0 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 AFZ81035.1 - 3.4e-07 30.6 0.6 0.037 14.3 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.1 AFZ81035.1 - 3.5e-07 30.4 8.7 0.031 14.4 0.0 5.4 5 1 0 5 5 5 2 AAA domain AAA_17 PF13207.1 AFZ81035.1 - 5.2e-07 30.5 3.1 0.0041 17.9 0.0 4.4 5 1 0 5 5 3 2 AAA domain IstB_IS21 PF01695.12 AFZ81035.1 - 1e-06 28.2 0.0 0.021 14.2 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 AFZ81035.1 - 1.3e-05 25.0 6.7 0.17 11.5 0.0 5.2 6 1 1 7 7 4 2 Archaeal ATPase Torsin PF06309.6 AFZ81035.1 - 0.00014 21.7 0.0 0.0006 19.7 0.0 2.0 2 0 0 2 2 1 1 Torsin Mg_chelatase PF01078.16 AFZ81035.1 - 0.00014 21.0 0.0 1.6 7.8 0.0 3.4 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 AFZ81035.1 - 0.00026 21.1 0.0 0.29 11.3 0.0 2.9 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 AFZ81035.1 - 0.00033 19.8 0.0 0.0093 15.0 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin RuvB_N PF05496.7 AFZ81035.1 - 0.00033 19.7 4.4 0.17 10.9 0.0 3.6 3 1 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus Bac_DnaA PF00308.13 AFZ81035.1 - 0.00043 20.0 0.0 0.41 10.2 0.0 3.6 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_19 PF13245.1 AFZ81035.1 - 0.00054 19.6 0.0 0.54 10.0 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain NACHT PF05729.7 AFZ81035.1 - 0.00056 19.6 0.0 0.4 10.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 AFZ81035.1 - 0.0009 19.5 1.3 0.059 13.6 0.0 3.4 3 1 0 3 3 2 1 ABC transporter MMR_HSR1 PF01926.18 AFZ81035.1 - 0.00094 19.1 0.0 0.18 11.7 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 AFZ81035.1 - 0.0018 17.9 0.0 0.27 10.9 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 AFZ81035.1 - 0.002 17.8 1.2 3 7.5 0.0 3.8 4 0 0 4 4 4 1 NTPase ResIII PF04851.10 AFZ81035.1 - 0.0023 17.8 0.2 0.094 12.5 0.0 3.1 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 AFZ81035.1 - 0.0033 17.4 0.3 5.4 6.9 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_24 PF13479.1 AFZ81035.1 - 0.0036 16.8 0.0 2.9 7.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AFZ81035.1 - 0.0038 16.4 0.0 2.5 7.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 AFZ81035.1 - 0.0044 16.6 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 AFZ81035.1 - 0.0046 16.5 0.0 1.1 8.8 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 AFZ81035.1 - 0.0057 16.1 2.6 0.15 11.5 0.0 3.7 3 1 0 3 3 3 1 AAA-like domain AAA_25 PF13481.1 AFZ81035.1 - 0.0098 15.3 0.5 1.2 8.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 AFZ81035.1 - 0.013 14.4 0.0 0.044 12.6 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 AFZ81035.1 - 0.013 15.8 0.2 8.5 6.6 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AFZ81035.1 - 0.031 14.1 0.0 2.3 8.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 AFZ81035.1 - 0.035 14.6 0.0 1.6 9.2 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 AFZ81035.1 - 0.042 13.3 0.0 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AP2 PF00847.15 AFZ81037.1 - 2.8e-11 43.3 0.0 6.3e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 AP2 domain Glutaredoxin PF00462.19 AFZ81038.1 - 1.6e-14 53.6 0.0 3.3e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Ribosomal_L7Ae PF01248.21 AFZ81039.1 - 1.9e-16 59.3 0.4 3.3e-16 58.5 0.3 1.5 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Sulfolobus_pRN PF05584.6 AFZ81039.1 - 0.036 14.0 0.4 0.06 13.3 0.3 1.3 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein EMG1 PF03587.9 AFZ81039.1 - 0.078 12.2 0.1 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase Ran_BP1 PF00638.13 AFZ81041.1 - 1.4e-37 128.4 0.4 2.3e-37 127.7 0.3 1.3 1 0 0 1 1 1 1 RanBP1 domain Abhydrolase_6 PF12697.2 AFZ81042.1 - 3.2e-15 56.6 0.0 9.9e-15 55.0 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ81042.1 - 8.6e-11 41.7 0.0 4.2e-10 39.5 0.0 2.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ81042.1 - 3.6e-09 36.3 0.5 7.2e-08 32.1 0.1 2.9 3 0 0 3 3 3 1 Putative lysophospholipase FAINT PF04385.10 AFZ81042.1 - 0.00017 21.3 13.8 0.014 15.2 0.5 4.5 4 1 0 4 4 4 2 Domain of unknown function, DUF529 Abhydrolase_1 PF00561.15 AFZ81042.1 - 0.0024 17.4 0.2 0.81 9.2 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 AFZ81042.1 - 0.0055 16.1 0.1 6.1 6.2 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 AFZ81042.1 - 0.0067 16.0 0.0 0.039 13.5 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 AFZ81042.1 - 0.025 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DUF2305 PF10230.4 AFZ81042.1 - 0.05 13.0 0.2 0.14 11.5 0.2 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) MMS1_N PF10433.4 AFZ81043.1 - 5.9e-87 291.9 0.0 9e-87 291.3 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 AFZ81043.1 - 3.2e-78 263.0 0.0 4.5e-77 259.2 0.0 2.9 4 1 0 4 4 4 1 CPSF A subunit region BBS2_Mid PF14783.1 AFZ81043.1 - 0.0012 18.6 0.3 0.69 9.7 0.0 3.9 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region CPW_WPC PF09717.5 AFZ81044.1 - 4.7e-17 62.3 4.6 6.6e-17 61.8 1.5 2.0 2 0 0 2 2 2 1 Plasmodium falciparum domain of unknown function (CPW_WPC) CPW_WPC PF09717.5 AFZ81046.1 - 6.3e-73 241.3 51.9 1.6e-14 54.2 2.4 7.4 7 1 0 7 7 7 7 Plasmodium falciparum domain of unknown function (CPW_WPC) POTRA_2 PF08479.6 AFZ81047.1 - 0.01 15.4 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 POTRA domain, ShlB-type SMK-1 PF04802.10 AFZ81047.1 - 0.02 14.4 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Component of IIS longevity pathway SMK-1 DIX PF00778.12 AFZ81048.1 - 0.019 14.6 0.1 0.077 12.7 0.0 2.1 1 0 0 1 1 1 0 DIX domain Cwf_Cwc_15 PF04889.7 AFZ81049.1 - 0.0071 16.0 19.7 0.0071 16.0 13.7 1.6 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein CTP_transf_2 PF01467.21 AFZ81050.1 - 8.1e-29 100.7 0.0 3.3e-14 53.2 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 AFZ81050.1 - 1.2e-05 24.9 0.3 0.13 11.8 0.0 3.2 2 1 0 2 2 2 2 FAD synthetase Pantoate_ligase PF02569.10 AFZ81050.1 - 0.022 13.5 0.0 0.15 10.7 0.0 2.2 3 0 0 3 3 3 0 Pantoate-beta-alanine ligase DUF1153 PF06627.6 AFZ81051.1 - 0.084 12.7 0.0 0.77 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1153) SF-assemblin PF06705.6 AFZ81052.1 - 9.5e-40 136.2 22.5 1.3e-39 135.8 15.6 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin Baculo_PEP_C PF04513.7 AFZ81052.1 - 0.0017 18.1 14.0 0.0089 15.8 2.9 2.7 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.8 AFZ81052.1 - 0.0034 17.1 0.3 0.018 14.7 0.2 2.3 2 0 0 2 2 2 1 Lipoprotein leucine-zipper DUF1664 PF07889.7 AFZ81052.1 - 0.23 11.2 16.7 2.3 8.0 1.7 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) UPF0184 PF03670.8 AFZ81052.1 - 0.48 10.6 9.3 11 6.2 0.1 4.3 4 1 0 4 4 4 0 Uncharacterised protein family (UPF0184) Toxin_52 PF15605.1 AFZ81052.1 - 1.5 8.7 7.3 0.49 10.3 0.2 3.4 3 1 2 5 5 5 0 Putative toxin 52 YlqD PF11068.3 AFZ81052.1 - 5.1 7.1 16.8 1.4 8.9 2.9 2.9 1 1 2 3 3 3 0 YlqD protein NPV_P10 PF05531.7 AFZ81052.1 - 7.9 6.8 9.0 4.9e+02 1.0 6.1 3.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein WD40 PF00400.27 AFZ81053.1 - 8.2e-13 47.7 1.9 4.3e-08 32.7 0.0 2.6 3 1 0 3 3 3 2 WD domain, G-beta repeat ESSS PF10183.4 AFZ81054.1 - 0.12 12.7 1.1 4.8 7.6 0.1 3.2 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) FAM176 PF14851.1 AFZ81055.1 - 0.32 10.6 1.8 1.2 8.8 1.3 1.9 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 AFZ81055.1 - 0.39 8.7 5.1 0.63 8.0 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 AFZ81055.1 - 0.63 10.0 8.2 1.9 8.4 5.7 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TRAP_alpha PF03896.11 AFZ81055.1 - 1.8 7.4 5.8 3.8 6.4 4.0 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.5 AFZ81055.1 - 5.3 7.3 12.3 15 5.8 8.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 AFZ81055.1 - 5.4 7.3 10.5 29 5.0 7.3 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 AFZ81056.1 - 1.5e-05 24.6 11.7 0.0093 15.8 0.0 5.2 5 2 0 5 5 5 2 WD domain, G-beta repeat NAP PF00956.13 AFZ81057.1 - 2.1e-19 69.6 0.0 6.2e-18 64.8 0.0 2.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) WD40 PF00400.27 AFZ81058.1 - 1.1e-06 28.2 4.9 0.063 13.1 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat FAST_1 PF06743.10 AFZ81059.1 - 5.4e-11 42.0 0.1 0.00018 21.1 0.0 4.4 3 1 1 4 4 4 3 FAST kinase-like protein, subdomain 1 rpo132 PF12415.3 AFZ81059.1 - 0.029 13.3 0.2 0.13 11.2 0.0 2.3 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase Methyltransf_11 PF08241.7 AFZ81060.1 - 2.2e-07 31.2 0.0 4.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AFZ81060.1 - 6.8e-06 25.7 0.2 8.7e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AFZ81060.1 - 7.2e-05 23.3 0.0 0.00013 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AFZ81060.1 - 0.00032 21.1 0.3 0.0012 19.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AFZ81060.1 - 0.002 17.8 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Extensin_2 PF04554.8 AFZ81061.1 - 2 8.3 11.7 5.9 6.8 8.2 1.7 1 1 0 1 1 1 0 Extensin-like region HlyIII PF03006.15 AFZ81062.1 - 6.8e-19 68.1 19.7 8.1e-19 67.9 13.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related K1 PF02960.9 AFZ81062.1 - 0.058 13.4 0.3 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 K1 glycoprotein HEAT_2 PF13646.1 AFZ81063.1 - 0.0011 19.2 0.0 0.19 12.0 0.0 3.3 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 AFZ81063.1 - 0.0014 18.5 0.2 1.4 9.1 0.0 3.8 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 AFZ81063.1 - 0.011 16.2 0.0 9 6.9 0.0 2.9 2 0 0 2 2 2 0 HEAT-like repeat Arm PF00514.18 AFZ81063.1 - 0.081 12.7 4.4 0.25 11.2 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF2719 PF10891.3 AFZ81064.1 - 0.0082 15.8 0.0 0.027 14.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2719) F5_F8_type_C PF00754.20 AFZ81067.1 - 5.4e-13 48.8 1.0 8.6e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 F5/8 type C domain LCCL PF03815.14 AFZ81067.1 - 7.1e-12 45.1 0.0 7.1e-12 45.1 0.0 2.8 3 0 0 3 3 3 1 LCCL domain Ricin_B_lectin PF00652.17 AFZ81067.1 - 3.4e-08 33.5 0.7 1.4e-07 31.5 0.5 2.1 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Laminin_G_2 PF02210.19 AFZ81067.1 - 0.00038 20.5 0.4 0.0086 16.1 0.2 2.8 2 0 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.18 AFZ81067.1 - 0.013 15.4 0.1 0.068 13.1 0.0 2.1 2 0 0 2 2 2 0 Laminin G domain Polysacc_syn_2C PF08485.5 AFZ81067.1 - 0.035 13.5 0.1 0.21 11.0 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal ADIP PF11559.3 AFZ81067.1 - 0.042 13.7 0.1 0.042 13.7 0.1 2.9 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding zf-H2C2_2 PF13465.1 AFZ81069.1 - 0.058 13.7 0.7 0.13 12.6 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger double domain C2 PF00168.25 AFZ81070.1 - 6.5e-05 22.6 0.0 0.32 10.8 0.0 4.2 3 0 0 3 3 3 2 C2 domain Adaptin_N PF01602.15 AFZ81071.1 - 4.3e-84 282.7 15.3 4.9e-81 272.6 6.7 2.0 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 AFZ81071.1 - 0.0048 17.1 1.5 0.46 10.7 0.0 3.9 5 0 0 5 5 5 1 HEAT repeats Cnd1 PF12717.2 AFZ81071.1 - 0.045 13.5 0.1 0.045 13.5 0.1 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CD99L2 PF12301.3 AFZ81071.1 - 0.21 11.2 1.9 0.39 10.3 1.3 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 STAG PF08514.6 AFZ81072.1 - 0.005 16.5 0.1 0.005 16.5 0.1 2.9 3 0 0 3 3 3 1 STAG domain Ribosomal_L28 PF00830.14 AFZ81073.1 - 0.00015 21.5 0.3 0.0005 19.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal L28 family H_PPase PF03030.11 AFZ81074.1 - 3e-22 78.6 28.2 1.1e-11 43.8 4.0 3.0 3 0 0 3 3 3 3 Inorganic H+ pyrophosphatase DUF167 PF02594.11 AFZ81075.1 - 2.6e-23 81.7 0.4 3.2e-23 81.4 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Thioredoxin PF00085.15 AFZ81076.1 - 5.3e-27 93.5 0.1 5.9e-27 93.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AFZ81076.1 - 2.3e-07 30.8 0.0 3.4e-05 23.8 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 AFZ81076.1 - 1.3e-06 28.5 0.1 1.9e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 AFZ81076.1 - 0.00036 20.0 0.1 0.0014 18.1 0.0 1.7 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 AFZ81076.1 - 0.00043 19.9 0.0 0.0005 19.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 AFZ81076.1 - 0.0017 18.3 0.1 0.0028 17.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 AFZ81076.1 - 0.027 14.0 0.0 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.15 AFZ81076.1 - 0.051 13.1 1.1 3.3 7.2 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain TrbC_Ftype PF09673.5 AFZ81076.1 - 0.087 12.4 0.0 0.09 12.3 0.0 1.3 1 1 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein DUF2077 PF09850.4 AFZ81077.1 - 0.005 16.2 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2077) HEAT_EZ PF13513.1 AFZ81078.1 - 5e-17 61.8 1.3 6.3e-07 29.7 0.0 8.0 6 2 1 7 7 7 3 HEAT-like repeat HEAT PF02985.17 AFZ81078.1 - 1.9e-16 58.5 7.6 0.0042 17.0 0.0 9.6 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.1 AFZ81078.1 - 2.7e-12 46.7 0.0 0.00014 22.0 0.0 6.2 4 2 3 7 7 7 2 HEAT repeats IBN_N PF03810.14 AFZ81078.1 - 4.9e-06 26.3 0.1 0.00018 21.3 0.0 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 AFZ81078.1 - 0.00013 21.6 2.0 0.12 12.2 0.1 5.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 AFZ81078.1 - 0.034 14.5 0.4 13 6.1 0.0 4.3 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region AMP-binding PF00501.23 AFZ81079.1 - 8.5e-89 297.8 0.0 1e-88 297.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AFZ81079.1 - 2.4e-18 66.8 0.1 1.1e-17 64.6 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain zf-CCCH_2 PF14608.1 AFZ81080.1 - 5.4e-14 51.5 16.8 8.6e-07 28.7 2.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 AFZ81080.1 - 2.6e-08 33.3 6.0 0.0011 18.5 0.3 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CART PF06373.6 AFZ81080.1 - 0.32 10.9 5.8 0.27 11.2 1.1 2.7 2 1 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) zf-CCHH PF10283.4 AFZ81080.1 - 0.38 10.6 8.8 2.2 8.1 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger (CX5CX6HX5H) motif Opy2 PF09463.5 AFZ81080.1 - 0.41 10.7 1.9 24 5.1 0.1 2.4 1 1 1 2 2 2 0 Opy2 protein DnaI_N PF07319.6 AFZ81081.1 - 0.082 13.1 0.5 0.34 11.1 0.2 2.0 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus WD40 PF00400.27 AFZ81083.1 - 4.9e-06 26.2 2.0 0.53 10.2 0.0 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ PF01011.16 AFZ81083.1 - 0.00044 19.6 0.4 0.42 10.2 0.0 3.9 4 0 0 4 4 4 2 PQQ enzyme repeat Mago_nashi PF02792.9 AFZ81084.1 - 7.4e-71 236.4 0.9 8.5e-71 236.2 0.7 1.0 1 0 0 1 1 1 1 Mago nashi protein Ipi1_N PF12333.3 AFZ81085.1 - 0.038 13.9 0.2 2.4 8.1 0.0 3.5 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation DUF2508 PF10704.4 AFZ81085.1 - 0.12 12.5 1.4 14 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Bromodomain PF00439.20 AFZ81086.1 - 1.1e-16 60.4 0.1 2.7e-16 59.2 0.1 1.7 1 0 0 1 1 1 1 Bromodomain LST1 PF05083.8 AFZ81087.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 LST-1 protein MS_channel PF00924.13 AFZ81088.1 - 7.9e-16 58.0 0.7 1.8e-15 56.8 0.5 1.7 1 0 0 1 1 1 1 Mechanosensitive ion channel Pescadillo_N PF06732.6 AFZ81089.1 - 6.5e-82 274.9 1.2 1e-81 274.2 0.8 1.3 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.21 AFZ81089.1 - 0.053 13.6 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Prefoldin PF02996.12 AFZ81090.1 - 2.3e-12 46.6 0.0 2.8e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Adeno_E1B_19K PF01691.11 AFZ81090.1 - 0.032 13.5 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Rad51 PF08423.6 AFZ81091.1 - 9.4e-126 417.9 0.1 1.1e-124 414.4 0.0 1.9 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 AFZ81091.1 - 1.3e-11 44.2 0.0 2.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 AFZ81091.1 - 8.3e-09 34.9 0.0 1.2e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 AFZ81091.1 - 8.3e-05 21.8 0.1 0.00019 20.6 0.1 1.7 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 AFZ81091.1 - 0.00076 19.5 0.0 0.0019 18.3 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_22 PF13401.1 AFZ81091.1 - 0.053 13.6 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain MS_channel PF00924.13 AFZ81092.1 - 3e-07 29.9 2.6 3e-07 29.9 1.8 2.1 2 0 0 2 2 2 1 Mechanosensitive ion channel Med26 PF08711.6 AFZ81094.1 - 3.9e-08 32.6 0.1 9.8e-08 31.3 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Nucleoporin_FG PF13634.1 AFZ81095.1 - 3.4e-05 24.0 68.3 7.3e+03 -2.9 47.3 2.5 1 1 0 1 1 1 0 Nucleoporin FG repeat region DUF1134 PF06577.7 AFZ81095.1 - 0.055 12.9 0.2 0.082 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) DnaJ PF00226.26 AFZ81096.1 - 1.2e-18 66.5 3.0 1.2e-18 66.5 2.1 2.5 2 0 0 2 2 2 1 DnaJ domain TINF2_N PF14973.1 AFZ81096.1 - 0.048 13.7 4.1 0.66 10.0 0.4 2.2 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus MitMem_reg PF13012.1 AFZ81097.1 - 4.5e-32 110.5 0.1 9.3e-32 109.5 0.0 1.5 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 AFZ81097.1 - 7.2e-26 90.1 0.0 2.6e-25 88.3 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2423 PF10338.4 AFZ81098.1 - 3.1e-08 33.4 0.8 4.7e-08 32.8 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Ribosomal_L36e PF01158.13 AFZ81099.1 - 1.1e-34 118.2 0.4 1.4e-34 117.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e Bystin PF05291.6 AFZ81100.1 - 8.4e-105 350.0 0.7 1.3e-104 349.4 0.5 1.2 1 0 0 1 1 1 1 Bystin DUF4414 PF14377.1 AFZ81100.1 - 0.023 14.5 0.3 0.077 12.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) MitMem_reg PF13012.1 AFZ81100.1 - 0.1 12.6 0.5 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Occludin_ELL PF07303.8 AFZ81102.1 - 0.19 12.4 1.9 10 6.9 0.0 2.5 2 0 0 2 2 2 0 Occludin homology domain MIF4G PF02854.14 AFZ81103.1 - 8.7e-26 90.6 2.9 1.9e-25 89.5 2.0 1.6 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.10 AFZ81103.1 - 1.2e-07 30.7 4.3 0.014 14.9 0.0 2.8 2 0 0 2 2 2 2 Ataxin-2 C-terminal region MA3 PF02847.12 AFZ81103.1 - 0.025 14.3 0.3 0.097 12.3 0.2 2.1 1 0 0 1 1 1 0 MA3 domain DUF2363 PF10155.4 AFZ81103.1 - 0.14 12.1 6.0 1.5 8.7 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2363) RF-1 PF00472.15 AFZ81104.1 - 1.6e-34 118.0 4.4 2.5e-34 117.5 3.0 1.3 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 AFZ81104.1 - 9.3e-17 60.7 0.0 2.6e-16 59.3 0.0 1.8 1 1 0 1 1 1 1 PCRF domain MIR PF02815.14 AFZ81104.1 - 0.0063 16.0 1.1 0.0082 15.6 0.2 1.6 2 0 0 2 2 2 1 MIR domain HAD_2 PF13419.1 AFZ81105.1 - 0.00013 22.2 0.2 0.0047 17.1 0.1 2.6 1 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 AFZ81105.1 - 0.00016 21.3 0.0 0.0005 19.7 0.0 1.8 2 0 0 2 2 2 1 Acid Phosphatase Hydrolase_like PF13242.1 AFZ81105.1 - 0.00078 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like PilJ PF13675.1 AFZ81105.1 - 0.16 12.3 0.0 0.44 10.8 0.0 1.7 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term zf-primase PF09329.6 AFZ81106.1 - 8.3e-09 34.9 1.2 8.3e-09 34.9 0.9 2.4 3 0 0 3 3 3 1 Primase zinc finger DUF3782 PF12644.2 AFZ81106.1 - 0.15 11.8 1.3 0.6 9.9 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) FYDLN_acid PF09538.5 AFZ81106.1 - 0.18 12.4 4.7 0.076 13.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DZR PF12773.2 AFZ81106.1 - 3.6 7.4 9.1 94 2.9 0.5 2.6 1 1 1 2 2 2 0 Double zinc ribbon NUC153 PF08159.7 AFZ81108.1 - 3.1e-05 23.4 0.8 7e-05 22.3 0.5 1.6 1 0 0 1 1 1 1 NUC153 domain RabGAP-TBC PF00566.13 AFZ81109.1 - 7.7e-28 97.4 16.7 6.5e-14 51.9 5.5 2.7 1 1 1 2 2 2 2 Rab-GTPase-TBC domain Syntaxin-18_N PF10496.4 AFZ81109.1 - 0.0081 15.9 0.4 2.5 8.0 0.0 3.2 3 0 0 3 3 3 2 SNARE-complex protein Syntaxin-18 N-terminus FKBP_C PF00254.23 AFZ81110.1 - 0.0041 17.1 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GreA_GreB PF01272.14 AFZ81110.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term Sec1 PF00995.18 AFZ81111.1 - 5e-118 395.1 19.3 5.7e-118 394.9 13.4 1.0 1 0 0 1 1 1 1 Sec1 family EF_TS PF00889.14 AFZ81112.1 - 2.4e-30 105.5 2.9 3.3e-14 52.7 0.0 2.1 1 1 0 2 2 2 2 Elongation factor TS Imm47 PF15586.1 AFZ81112.1 - 0.028 14.2 0.1 0.058 13.2 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 47 AAA_31 PF13614.1 AFZ81112.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF445 PF04286.7 AFZ81112.1 - 0.13 11.7 1.7 0.34 10.3 1.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Thioredoxin PF00085.15 AFZ81113.1 - 4.2e-06 26.3 0.1 6.3e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AFZ81113.1 - 0.056 13.5 0.5 0.5 10.5 0.4 2.2 1 1 0 1 1 1 0 Thioredoxin-like NTase_sub_bind PF08780.6 AFZ81113.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like AMMECR1 PF01871.12 AFZ81115.1 - 1.2e-45 154.6 0.0 1.5e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 RRN3 PF05327.6 AFZ81116.1 - 4.4e-52 176.9 15.1 2.4e-51 174.5 10.5 2.1 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DUF3223 PF11523.3 AFZ81116.1 - 1.4e-06 28.4 0.1 5.8e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3223) CENP-C_C PF11699.3 AFZ81118.1 - 0.0096 15.8 0.8 0.033 14.1 0.6 1.9 1 0 0 1 1 1 1 Mif2/CENP-C like CAF1 PF04857.15 AFZ81119.1 - 2.8e-40 138.3 0.2 3.4e-40 138.0 0.1 1.0 1 0 0 1 1 1 1 CAF1 family ribonuclease PUF PF00806.14 AFZ81120.1 - 4.3e-55 180.1 12.8 1.2e-08 33.9 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat WD40 PF00400.27 AFZ81121.1 - 3.7e-40 134.4 17.3 2.2e-09 36.8 1.9 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 AFZ81121.1 - 0.00029 20.5 1.5 0.21 11.2 0.0 2.6 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term CLTH PF10607.4 AFZ81121.1 - 0.0088 15.7 0.0 0.03 14.0 0.0 1.9 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DEAD PF00270.24 AFZ81122.1 - 3e-40 137.4 0.0 2.5e-38 131.2 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ81122.1 - 9.8e-28 95.8 1.3 1.3e-27 95.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AFZ81122.1 - 0.023 14.8 0.0 0.44 10.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain SDP_N PF12278.3 AFZ81122.1 - 5.6 6.5 26.0 0.55 9.8 13.5 2.4 1 1 1 2 2 2 0 Sex determination protein N terminal Ribosomal_S24e PF01282.14 AFZ81123.1 - 4.4e-28 96.8 0.0 7e-28 96.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e SAP30_Sin3_bdg PF13867.1 AFZ81123.1 - 0.016 15.0 0.6 0.31 10.9 0.1 2.4 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 VIT1 PF01988.14 AFZ81123.1 - 0.024 14.1 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 VIT family UbiA PF01040.13 AFZ81124.1 - 2.2e-24 86.0 11.3 2.8e-24 85.7 7.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family eIF2A PF08662.6 AFZ81125.1 - 9e-30 103.8 0.1 2e-23 83.1 0.9 4.5 3 2 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 AFZ81125.1 - 6.3e-05 22.6 0.2 21 5.2 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat RRM_1 PF00076.17 AFZ81125.1 - 0.0029 17.2 0.0 0.0098 15.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DivIC PF04977.10 AFZ81125.1 - 0.25 10.8 2.1 0.55 9.7 1.4 1.5 1 0 0 1 1 1 0 Septum formation initiator p25-alpha PF05517.7 AFZ81126.1 - 5.3e-08 33.2 0.2 8.8e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 p25-alpha DCX PF03607.12 AFZ81126.1 - 6.6e-08 32.0 0.0 1.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Doublecortin AP2 PF00847.15 AFZ81127.1 - 3.1e-09 36.8 9.4 5.8e-06 26.3 0.2 2.8 3 0 0 3 3 3 2 AP2 domain zf-C3HC4_4 PF15227.1 AFZ81128.1 - 0.00046 20.0 0.7 0.00046 20.0 0.5 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 AFZ81128.1 - 0.00095 19.1 0.5 0.0022 17.9 0.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AFZ81128.1 - 0.049 13.2 0.5 0.12 12.0 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 AFZ81128.1 - 0.1 11.7 6.1 0.37 9.9 0.1 3.1 1 1 2 3 3 3 0 Rtf2 RING-finger zf-RING_2 PF13639.1 AFZ81128.1 - 0.1 12.4 0.8 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 Ring finger domain Peptidase_S49_N PF08496.5 AFZ81128.1 - 0.3 10.8 1.4 0.56 9.9 1.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-B_box PF00643.19 AFZ81129.1 - 2.2e-14 53.0 12.2 1.2e-07 31.4 2.5 2.5 2 0 0 2 2 2 2 B-box zinc finger PARP PF00644.15 AFZ81129.1 - 2.9e-06 26.8 0.1 9e-06 25.2 0.1 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Cript PF10235.4 AFZ81129.1 - 2.9 8.2 14.0 0.34 11.2 4.7 2.4 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT NIF PF03031.13 AFZ81131.1 - 1.9e-40 138.1 0.6 3.5e-40 137.2 0.3 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BolA PF01722.13 AFZ81131.1 - 1.1e-19 70.1 0.0 2.5e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 BolA-like protein Ribosomal_S11 PF00411.14 AFZ81133.1 - 3e-41 140.0 0.2 4e-41 139.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 AFZ81133.1 - 0.024 13.5 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Toprim_3 PF13362.1 AFZ81133.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Toprim domain PseudoU_synth_1 PF01416.15 AFZ81134.1 - 5e-27 94.3 0.0 2.4e-15 56.8 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase GTP_EFTU PF00009.22 AFZ81136.1 - 3.8e-19 68.8 1.1 3.6e-17 62.3 0.8 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AFZ81136.1 - 4.3e-10 39.5 0.1 1.1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF-2 PF11987.3 AFZ81136.1 - 9.9e-07 28.6 3.1 2.8e-06 27.1 2.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 PduV-EutP PF10662.4 AFZ81136.1 - 2.3e-05 23.8 0.5 5.6e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 AFZ81136.1 - 0.00013 21.2 0.0 0.00029 20.0 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 AFZ81136.1 - 0.00018 21.3 0.0 0.42 10.4 0.0 2.7 1 1 1 2 2 2 2 Dynamin family Ras PF00071.17 AFZ81136.1 - 0.00064 19.1 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.13 AFZ81136.1 - 0.0015 17.7 0.1 0.0044 16.2 0.1 1.9 1 0 0 1 1 1 1 Ferrous iron transport protein B IF2_N PF04760.10 AFZ81136.1 - 0.0067 16.0 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 AFZ81136.1 - 0.016 15.6 0.0 0.052 14.0 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 AFZ81136.1 - 0.065 12.4 0.0 0.28 10.3 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 AFZ81136.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_L11_N PF03946.9 AFZ81138.1 - 2.8e-18 65.1 0.0 4e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AFZ81138.1 - 4.8e-11 42.6 0.0 8.2e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain STIL_N PF15253.1 AFZ81138.1 - 0.032 12.9 0.0 0.04 12.6 0.0 1.1 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus 7tm_1 PF00001.16 AFZ81139.1 - 0.0034 16.5 2.4 0.0034 16.5 1.6 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF4184 PF13803.1 AFZ81139.1 - 0.0036 16.6 1.9 0.012 14.8 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4184) HTH_9 PF08221.6 AFZ81140.1 - 4e-13 49.0 6.9 5e-12 45.5 0.1 4.3 5 0 0 5 5 5 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TrmB PF01978.14 AFZ81140.1 - 0.015 14.9 0.0 3 7.6 0.0 3.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.15 AFZ81140.1 - 0.021 14.9 0.5 9.7 6.3 0.0 3.3 3 0 0 3 3 3 0 Transcriptional regulator MotA_activ PF09114.5 AFZ81140.1 - 0.041 13.6 1.9 0.26 11.0 0.1 3.1 4 0 0 4 4 4 0 Transcription factor MotA, activation domain WD40 PF00400.27 AFZ81141.1 - 3.9e-84 273.7 30.2 1.8e-13 49.8 0.1 8.6 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 AFZ81141.1 - 3.5e-12 46.1 1.0 5.9e-12 45.4 0.7 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 AFZ81141.1 - 1.2e-09 36.9 4.1 0.015 13.4 0.3 4.1 2 2 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 AFZ81141.1 - 1.3e-05 23.6 0.0 0.0082 14.4 0.0 3.7 2 2 2 4 4 4 2 Cytochrome D1 heme domain KcnmB2_inactiv PF09303.5 AFZ81141.1 - 0.078 12.7 0.7 0.28 10.9 0.5 2.0 1 0 0 1 1 1 0 KCNMB2, ball and chain domain PD40 PF07676.7 AFZ81141.1 - 1.7 8.4 5.4 71 3.2 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RPAP1_C PF08620.5 AFZ81143.1 - 1.3e-21 76.2 0.0 2.9e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 AFZ81143.1 - 0.00016 21.1 2.7 0.0005 19.6 1.9 1.8 1 0 0 1 1 1 1 RPAP1-like, N-terminal Arm PF00514.18 AFZ81143.1 - 0.011 15.5 1.1 4.2 7.3 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat WD40 PF00400.27 AFZ81144.1 - 4.8e-66 216.4 33.8 6.7e-15 54.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 AFZ81144.1 - 0.0001 20.7 0.2 0.19 10.0 0.0 3.4 2 2 3 5 5 5 3 Cytochrome D1 heme domain PQQ_3 PF13570.1 AFZ81144.1 - 0.0065 16.7 1.9 0.089 13.0 0.0 3.4 3 1 0 3 3 3 1 PQQ-like domain SGL PF08450.7 AFZ81144.1 - 0.026 13.9 0.2 1.4 8.2 0.0 2.9 3 0 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 AFZ81144.1 - 0.045 12.5 7.3 0.27 9.9 0.1 3.7 2 2 2 4 4 4 0 Nup133 N terminal like Nup160 PF11715.3 AFZ81144.1 - 0.077 11.1 9.8 3.1 5.8 0.1 4.3 2 2 3 5 5 5 0 Nucleoporin Nup120/160 DUF4302 PF14135.1 AFZ81144.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) LRR_4 PF12799.2 AFZ81145.1 - 1.7e-39 132.7 45.2 2.7e-09 36.4 0.5 7.9 4 2 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AFZ81145.1 - 2.8e-32 110.2 66.4 4.4e-10 39.1 0.7 5.4 2 1 5 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 AFZ81145.1 - 3.7e-18 62.7 34.4 0.031 14.2 0.1 11.2 11 2 0 11 11 11 6 Leucine Rich Repeat LRR_6 PF13516.1 AFZ81145.1 - 5.1e-16 56.9 29.4 0.048 13.7 0.0 11.1 8 3 3 11 11 11 6 Leucine Rich repeat LRR_9 PF14580.1 AFZ81145.1 - 1e-13 51.2 13.8 3.4e-08 33.2 2.3 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_7 PF13504.1 AFZ81145.1 - 3.6e-12 44.3 26.9 0.17 12.2 0.0 11.4 11 2 2 13 13 13 5 Leucine rich repeat LRR_2 PF07723.8 AFZ81145.1 - 0.27 11.8 6.5 63 4.3 0.1 5.1 3 2 2 5 5 5 0 Leucine Rich Repeat SpoU_methylase PF00588.14 AFZ81146.1 - 8e-07 29.0 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family PCI PF01399.22 AFZ81148.1 - 1.9e-10 41.0 2.7 3.3e-10 40.2 0.2 2.4 2 1 0 2 2 2 1 PCI domain Colipase-like PF15083.1 AFZ81148.1 - 0.0022 17.8 3.1 0.007 16.2 0.1 2.7 3 0 0 3 3 3 1 Colipase-like PLATZ PF04640.9 AFZ81148.1 - 0.022 14.9 0.3 1.3 9.2 0.0 2.7 2 0 0 2 2 2 0 PLATZ transcription factor Peptidase_M22 PF00814.20 AFZ81149.1 - 2.9e-74 249.9 0.0 3.4e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family DUF3752 PF12572.3 AFZ81150.1 - 4.8e-08 33.2 2.8 4.8e-08 33.2 1.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Dynamin_M PF01031.15 AFZ81151.1 - 7e-82 274.5 2.6 7e-82 274.5 0.0 2.2 2 1 1 3 3 3 1 Dynamin central region Dynamin_N PF00350.18 AFZ81151.1 - 5.4e-46 156.4 0.0 1.7e-45 154.8 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 AFZ81151.1 - 1.3e-23 82.7 0.8 5.9e-23 80.5 0.1 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 AFZ81151.1 - 0.013 15.4 0.0 0.077 12.9 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase Adaptin_N PF01602.15 AFZ81152.1 - 6.7e-63 212.7 16.2 1.1e-62 212.0 11.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 AFZ81152.1 - 2.4e-16 59.9 6.6 6.4e-16 58.5 3.9 2.2 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 AFZ81152.1 - 1e-05 25.6 0.0 3.2 8.0 0.0 4.8 3 1 3 6 6 6 2 HEAT repeats HEAT PF02985.17 AFZ81152.1 - 0.025 14.6 0.0 31 4.9 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat DSS1_SEM1 PF05160.8 AFZ81153.1 - 0.0012 18.6 17.6 0.0029 17.3 12.1 1.8 1 1 0 1 1 1 1 DSS1/SEM1 family DUF1014 PF06244.7 AFZ81155.1 - 5.3e-25 87.9 3.5 5.3e-25 87.9 2.4 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 AFZ81155.1 - 0.033 14.4 0.3 0.033 14.4 0.2 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box Polysacc_synt_2 PF02719.10 AFZ81155.1 - 0.05 12.4 2.2 0.065 12.1 1.5 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-DHHC PF01529.15 AFZ81156.1 - 7.5e-34 116.6 12.3 7.5e-34 116.6 8.5 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase zf-CDGSH PF09360.5 AFZ81157.1 - 1.2e-08 34.6 1.9 1.4e-08 34.3 0.6 1.7 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type DUF553 PF04473.7 AFZ81157.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.2 1 1 0 1 1 1 0 Transglutaminase-like domain CDC73 PF05179.9 AFZ81158.1 - 7.8e-38 130.3 1.8 1.1e-37 129.8 1.3 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family NUDIX PF00293.23 AFZ81159.1 - 3.1e-21 75.4 0.0 3.7e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain Hemerythrin PF01814.18 AFZ81159.1 - 0.13 12.4 1.2 0.18 11.9 0.8 1.2 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain LSM PF01423.17 AFZ81160.1 - 2.9e-12 45.9 0.1 4.9e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 AFZ81160.1 - 0.0029 17.3 0.1 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain VWA PF00092.23 AFZ81161.1 - 9.2e-27 93.9 0.1 1.5e-26 93.1 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 AFZ81161.1 - 8.4e-10 39.0 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 AFZ81161.1 - 0.0012 18.7 0.1 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus TSP_1 PF00090.14 AFZ81161.1 - 0.1 12.7 1.9 0.35 11.0 0.0 2.4 2 0 0 2 2 2 0 Thrombospondin type 1 domain VWA_CoxE PF05762.9 AFZ81161.1 - 0.11 11.5 0.4 0.32 10.1 0.1 1.7 1 1 1 2 2 2 0 VWA domain containing CoxE-like protein VWA PF00092.23 AFZ81163.1 - 2.6e-31 108.7 0.0 4.6e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 AFZ81163.1 - 2.5e-10 40.7 0.0 4.9e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.14 AFZ81163.1 - 9.3e-05 22.4 8.5 0.00045 20.2 5.9 2.3 1 1 0 1 1 1 1 Thrombospondin type 1 domain vWA-TerF-like PF10138.4 AFZ81163.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus PTN_MK_C PF01091.13 AFZ81163.1 - 0.19 11.7 2.6 0.34 10.9 0.3 2.3 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, C-terminal domain Ribosomal_S4 PF00163.14 AFZ81166.1 - 6.4e-22 77.7 3.3 9.8e-22 77.1 2.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 AFZ81166.1 - 2.4e-13 49.2 0.2 8.4e-13 47.5 0.1 1.9 1 0 0 1 1 1 1 S4 domain SPT16 PF08644.6 AFZ81168.1 - 2.1e-49 167.2 3.1 3.8e-49 166.4 0.4 2.7 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 AFZ81168.1 - 3.1e-21 75.5 4.6 3.6e-21 75.3 0.0 2.9 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 AFZ81168.1 - 6.6e-21 74.0 0.1 3.7e-20 71.7 0.0 2.4 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 AFZ81168.1 - 3.6e-20 72.4 0.1 6.2e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 RRM_1 PF00076.17 AFZ81169.1 - 6.3e-31 105.8 0.1 1.2e-19 69.6 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ81169.1 - 3.6e-16 58.9 0.0 2.7e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ81169.1 - 5.4e-11 42.1 0.1 3.8e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AFZ81169.1 - 0.026 14.3 0.0 0.87 9.4 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif DUF3362 PF11842.3 AFZ81169.1 - 0.077 12.9 1.9 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3362) Corona_nucleoca PF00937.13 AFZ81169.1 - 9 5.1 14.8 13 4.5 10.3 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Transposase_24 PF03004.9 AFZ81170.1 - 0.021 14.7 4.3 0.031 14.1 0.7 2.3 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) Mit_KHE1 PF10173.4 AFZ81170.1 - 0.34 10.7 5.6 0.15 11.8 2.2 1.7 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Proteasome PF00227.21 AFZ81171.1 - 5.4e-35 120.3 0.6 6.4e-35 120.1 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF4432 PF14486.1 AFZ81172.1 - 0.0049 15.4 0.9 0.0089 14.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4432) TIG PF01833.19 AFZ81172.1 - 0.082 12.9 0.3 0.082 12.9 0.2 2.4 2 0 0 2 2 2 0 IPT/TIG domain Cyclin PF08613.6 AFZ81173.1 - 8.1e-32 110.6 1.6 1.4e-31 109.9 1.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AFZ81173.1 - 1.2e-12 47.5 0.4 1.8e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Tom37_C PF11801.3 AFZ81173.1 - 0.032 14.1 0.2 0.062 13.1 0.2 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain ATP-synt_C PF00137.16 AFZ81174.1 - 3.8e-30 103.5 28.5 2.7e-16 59.1 6.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.3 AFZ81174.1 - 0.038 13.5 0.5 0.038 13.5 0.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2970) PT-VENN PF04829.8 AFZ81174.1 - 9.8 5.8 6.5 83 2.8 4.5 2.1 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Ribosomal_L14 PF00238.14 AFZ81175.1 - 2.6e-19 69.1 0.5 5.2e-19 68.1 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SLBP_RNA_bind PF15247.1 AFZ81175.1 - 1.1e-13 50.7 1.7 1.9e-13 49.9 1.1 1.3 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain EssA PF10661.4 AFZ81176.1 - 0.14 11.7 1.8 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA tRNA-synt_1d PF00750.14 AFZ81177.1 - 3.1e-101 338.7 0.5 4.1e-101 338.3 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 AFZ81177.1 - 8.9e-30 103.0 0.0 2.4e-29 101.7 0.0 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 AFZ81177.1 - 7.8e-14 51.9 0.0 1.8e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 AFZ81177.1 - 4.7e-05 22.6 0.1 0.00011 21.4 0.1 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 AFZ81177.1 - 0.00066 18.4 1.5 0.029 13.0 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (M) Syd PF07348.7 AFZ81177.1 - 0.065 12.5 0.1 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Syd protein (SUKH-2) Tcf25 PF04910.9 AFZ81177.1 - 0.082 11.8 0.3 0.49 9.2 0.0 2.1 2 0 0 2 2 2 0 Transcriptional repressor TCF25 Abhydrolase_6 PF12697.2 AFZ81178.1 - 2e-14 54.0 0.0 2.9e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ81178.1 - 2e-11 43.8 0.0 3.7e-11 42.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ81178.1 - 2.1e-09 37.0 0.1 5.2e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 AFZ81178.1 - 0.00063 19.3 0.2 0.068 12.7 0.1 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 AFZ81178.1 - 0.0048 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.8 AFZ81178.1 - 0.0075 15.8 0.0 0.018 14.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 AFZ81178.1 - 0.016 14.5 0.0 0.032 13.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) NAD_binding_8 PF13450.1 AFZ81178.1 - 0.018 15.0 0.1 0.049 13.6 0.0 1.7 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Lipase_3 PF01764.20 AFZ81178.1 - 0.023 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.9 AFZ81178.1 - 0.056 12.7 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) FSH1 PF03959.8 AFZ81178.1 - 0.078 12.4 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 AFZ81178.1 - 0.09 11.9 0.0 6.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Cutinase PF01083.17 AFZ81178.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Cutinase DLH PF01738.13 AFZ81178.1 - 0.14 11.4 0.5 1.9 7.7 0.0 2.3 2 1 0 3 3 3 0 Dienelactone hydrolase family DUF3311 PF11755.3 AFZ81179.1 - 3.4 7.2 9.4 0.27 10.8 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) FAINT PF04385.10 AFZ81181.1 - 0.23 11.3 1.0 0.47 10.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function, DUF529 PI3_PI4_kinase PF00454.22 AFZ81182.1 - 2.6e-29 102.3 0.1 6.1e-29 101.1 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Ribosomal_L13 PF00572.13 AFZ81183.1 - 1.3e-25 89.9 0.0 1.9e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.15 AFZ81183.1 - 0.14 11.6 0.0 2.8 7.4 0.0 2.1 2 0 0 2 2 2 0 DSBA-like thioredoxin domain SNARE PF05739.14 AFZ81184.1 - 6.6e-13 48.1 1.2 6.6e-13 48.1 0.8 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 AFZ81184.1 - 6.8e-07 29.4 4.9 3.9e-06 26.9 0.2 2.9 1 1 2 3 3 3 1 Syntaxin Syntaxin_2 PF14523.1 AFZ81184.1 - 0.0015 18.5 7.4 0.13 12.2 0.4 3.2 2 1 1 3 3 3 2 Syntaxin-like protein DUF342 PF03961.8 AFZ81184.1 - 0.0038 15.7 0.9 0.0096 14.3 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF342) Synaptobrevin PF00957.16 AFZ81184.1 - 0.0056 16.2 1.0 0.0056 16.2 0.7 2.7 2 1 0 2 2 2 1 Synaptobrevin DUF4062 PF13271.1 AFZ81184.1 - 0.059 13.3 0.3 0.38 10.8 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4062) Aldedh PF00171.17 AFZ81184.1 - 0.076 11.3 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family IncA PF04156.9 AFZ81184.1 - 0.15 11.6 2.1 0.53 9.8 1.4 2.0 1 1 0 1 1 1 0 IncA protein ZYG-11_interact PF05884.7 AFZ81184.1 - 0.32 10.0 5.3 0.15 11.1 0.3 2.3 1 1 1 2 2 2 0 Interactor of ZYG-11 MCPsignal PF00015.16 AFZ81184.1 - 0.4 10.1 4.4 0.43 10.0 1.1 2.0 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Mt_ATP-synt_B PF05405.9 AFZ81184.1 - 0.52 9.7 4.8 0.15 11.5 0.5 2.0 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Syntaxin-6_N PF09177.6 AFZ81184.1 - 0.83 10.0 4.0 5.2 7.5 0.3 2.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal V-SNARE PF05008.10 AFZ81184.1 - 2.8 8.1 6.5 0.45 10.7 0.3 2.7 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus zf-met PF12874.2 AFZ81185.1 - 9.8e-08 31.9 1.0 1.7e-07 31.2 0.5 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AFZ81185.1 - 2.5e-07 30.6 0.7 4.7e-07 29.7 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 AFZ81185.1 - 0.0012 18.3 0.5 0.0024 17.3 0.3 1.4 1 0 0 1 1 1 1 U1 zinc finger Glyco_transf_41 PF13844.1 AFZ81185.1 - 0.24 9.3 1.2 0.28 9.0 0.4 1.4 2 0 0 2 2 2 0 Glycosyl transferase family 41 Metal_resist PF13801.1 AFZ81185.1 - 1.9 8.5 7.2 40 4.2 0.0 2.5 1 1 0 2 2 2 0 Heavy-metal resistance Cytochrom_C1 PF02167.10 AFZ81186.1 - 8.5e-82 274.0 0.0 1.3e-81 273.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 AFZ81186.1 - 0.0022 18.0 0.0 0.0054 16.8 0.0 1.8 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 AFZ81186.1 - 0.0082 16.9 0.0 0.021 15.6 0.0 1.8 1 0 0 1 1 1 1 Cytochrome c Gp_dh_C PF02800.15 AFZ81187.1 - 1.8e-71 238.6 0.0 2.4e-71 238.2 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 AFZ81187.1 - 7.6e-54 181.7 0.1 2.3e-53 180.2 0.0 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 AFZ81187.1 - 0.0047 16.8 0.2 0.04 13.8 0.0 2.4 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus AAA PF00004.24 AFZ81189.1 - 6.5e-12 45.8 0.0 1.4e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 AFZ81189.1 - 4.6e-07 30.3 0.3 4.6e-07 30.3 0.2 2.2 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 AFZ81189.1 - 3e-06 27.0 0.0 5.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 AFZ81189.1 - 9.3e-06 25.9 0.1 5.6e-05 23.4 0.0 2.3 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 AFZ81189.1 - 1.5e-05 24.4 0.0 3.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain VirE PF05272.6 AFZ81189.1 - 0.00031 20.2 0.0 0.00064 19.2 0.0 1.5 1 0 0 1 1 1 1 Virulence-associated protein E AAA_25 PF13481.1 AFZ81189.1 - 0.00038 19.9 0.1 0.013 14.8 0.0 2.2 1 1 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 AFZ81189.1 - 0.00039 19.1 0.0 0.0006 18.5 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_16 PF13191.1 AFZ81189.1 - 0.00042 20.3 0.0 0.0012 18.9 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_15 PF13175.1 AFZ81189.1 - 0.00045 19.4 1.0 0.00045 19.4 0.7 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AFZ81189.1 - 0.00061 19.9 0.5 0.0043 17.2 0.2 2.6 2 2 1 3 3 3 1 AAA domain AAA_18 PF13238.1 AFZ81189.1 - 0.003 17.8 0.0 0.0079 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 AFZ81189.1 - 0.0053 16.7 0.2 0.0053 16.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AFZ81189.1 - 0.015 14.7 0.3 0.091 12.1 0.0 2.1 1 1 1 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 AFZ81189.1 - 0.015 15.4 0.1 0.047 13.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 AFZ81189.1 - 0.015 15.2 0.1 0.071 13.0 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.14 AFZ81189.1 - 0.022 14.0 0.1 0.069 12.3 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 AFZ81189.1 - 0.025 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 AFZ81189.1 - 0.029 14.2 0.1 0.068 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AFZ81189.1 - 0.033 13.9 0.1 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 AFZ81189.1 - 0.035 13.3 0.0 0.11 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 AFZ81189.1 - 0.038 14.4 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_30 PF13604.1 AFZ81189.1 - 0.038 13.5 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 AFZ81189.1 - 0.052 12.4 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 AFZ81189.1 - 0.059 14.1 0.2 0.16 12.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AFZ81189.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.1 AFZ81190.1 - 3.9e-17 62.3 1.3 1.2e-15 57.5 0.2 2.6 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 AFZ81190.1 - 2.5e-16 59.4 1.2 5.1e-16 58.4 0.1 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.24 AFZ81190.1 - 1.8e-15 57.2 0.0 3.8e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AFZ81190.1 - 3e-13 49.3 0.1 1.1e-10 40.8 0.1 2.0 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AFZ81190.1 - 5.3e-08 33.0 0.7 2.4e-07 30.9 0.2 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 AFZ81190.1 - 1.8e-07 30.9 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AFZ81190.1 - 1.9e-06 27.6 0.4 6e-05 22.7 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 AFZ81190.1 - 3.7e-06 27.0 0.0 3.9e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 AFZ81190.1 - 4.4e-06 25.9 0.1 2.1e-05 23.6 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AFZ81190.1 - 3.4e-05 23.5 0.0 9.8e-05 22.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 AFZ81190.1 - 4.8e-05 23.2 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AFZ81190.1 - 0.00013 21.6 0.1 0.00029 20.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.24 AFZ81190.1 - 0.00014 21.3 0.3 0.0035 16.8 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 AFZ81190.1 - 0.00065 18.7 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 AFZ81190.1 - 0.00071 19.8 0.1 0.0023 18.2 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.1 AFZ81190.1 - 0.0015 18.8 1.1 0.0035 17.7 0.8 1.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 AFZ81190.1 - 0.0019 18.0 0.2 0.028 14.2 0.1 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_17 PF13207.1 AFZ81190.1 - 0.0052 17.6 0.0 0.013 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AFZ81190.1 - 0.0068 15.5 0.1 0.034 13.2 0.0 2.0 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 AFZ81190.1 - 0.017 14.6 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TIP49 PF06068.8 AFZ81190.1 - 0.022 13.4 0.2 0.16 10.6 0.0 2.2 3 0 0 3 3 3 0 TIP49 C-terminus AAA_10 PF12846.2 AFZ81190.1 - 0.038 13.4 0.4 0.55 9.6 0.3 2.5 1 1 0 1 1 1 0 AAA-like domain SRP54 PF00448.17 AFZ81190.1 - 0.044 13.2 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SNF2_N PF00176.18 AFZ81190.1 - 0.053 12.3 0.3 0.51 9.0 0.0 2.2 3 0 0 3 3 3 0 SNF2 family N-terminal domain AAA_33 PF13671.1 AFZ81190.1 - 0.057 13.2 0.2 0.11 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AFZ81190.1 - 0.064 13.4 0.2 0.26 11.4 0.1 2.1 1 1 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 AFZ81190.1 - 0.065 12.7 0.0 0.19 11.1 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_3 PF07726.6 AFZ81190.1 - 0.067 12.7 0.1 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 AFZ81190.1 - 0.13 11.9 0.1 1.1 8.9 0.1 2.2 1 1 0 1 1 1 0 NTPase Zot PF05707.7 AFZ81190.1 - 0.14 11.6 0.1 0.64 9.4 0.1 2.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) CBFD_NFYB_HMF PF00808.18 AFZ81191.1 - 0.00016 21.6 1.0 0.00023 21.1 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AFZ81191.1 - 0.00074 19.5 0.4 0.0011 19.0 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 WD40 PF00400.27 AFZ81192.1 - 1.8e-08 33.9 3.9 2.2 8.3 0.0 7.8 8 0 0 8 8 8 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 AFZ81192.1 - 0.071 12.8 0.1 17 5.2 0.0 3.6 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region RabGAP-TBC PF00566.13 AFZ81194.1 - 7e-48 162.9 2.6 9.3e-48 162.5 1.8 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Thioredoxin_8 PF13905.1 AFZ81195.1 - 5.2e-49 164.3 0.3 5.6e-23 80.8 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 AFZ81195.1 - 8.7e-09 35.5 0.0 0.00046 20.3 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 AFZ81195.1 - 1.1e-05 25.0 0.2 0.0037 16.9 0.0 3.3 4 0 0 4 4 4 1 AhpC/TSA family Thioredoxin_6 PF13848.1 AFZ81195.1 - 6.3e-05 22.8 7.8 0.00012 21.9 0.2 3.5 4 1 1 5 5 5 1 Thioredoxin-like domain SCO1-SenC PF02630.9 AFZ81195.1 - 0.033 13.7 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 SCO1/SenC HSP90 PF00183.13 AFZ81197.1 - 0.3 9.4 10.1 0.36 9.1 7.0 1.2 1 0 0 1 1 1 0 Hsp90 protein DUF4614 PF15391.1 AFZ81197.1 - 0.61 9.8 6.9 0.74 9.5 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DDRGK PF09756.4 AFZ81197.1 - 2.2 7.6 15.7 3 7.2 10.0 1.7 2 0 0 2 2 2 0 DDRGK domain DUF1510 PF07423.6 AFZ81197.1 - 2.2 7.5 15.7 2.6 7.3 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SR-25 PF10500.4 AFZ81197.1 - 2.8 7.3 21.8 4 6.8 15.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3807 PF12720.2 AFZ81197.1 - 6.9 6.7 14.1 8.4 6.5 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) GAGA_bind PF06217.7 AFZ81197.1 - 8.8 6.1 18.4 11 5.8 12.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family TP53IP5 PF15331.1 AFZ81197.1 - 8.8 6.1 13.6 12 5.7 9.4 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Cnd1 PF12717.2 AFZ81198.1 - 4e-45 153.8 4.4 4e-45 153.8 3.1 3.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 XRN_N PF03159.13 AFZ81199.1 - 2.7e-96 321.5 0.1 6.3e-96 320.3 0.1 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus VWA_2 PF13519.1 AFZ81200.1 - 0.004 17.2 0.0 0.0071 16.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain MA-Mit PF09245.5 AFZ81200.1 - 0.043 13.0 0.1 0.082 12.1 0.1 1.4 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen Ssl1 PF04056.9 AFZ81200.1 - 0.044 13.3 0.3 0.08 12.5 0.2 1.4 1 0 0 1 1 1 0 Ssl1-like Glutaredoxin PF00462.19 AFZ81200.1 - 0.061 13.3 0.5 0.3 11.1 0.0 2.3 3 0 0 3 3 3 0 Glutaredoxin tRNA-synt_1b PF00579.20 AFZ81201.1 - 1.7e-50 171.8 0.0 2.2e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Proteasome PF00227.21 AFZ81202.1 - 9.7e-29 100.0 0.1 1.8e-28 99.1 0.0 1.5 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AFZ81202.1 - 1.7e-13 49.5 0.0 3.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Peptidase_S9 PF00326.16 AFZ81203.1 - 1.8e-25 89.4 0.0 2.9e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family ENTH PF01417.15 AFZ81203.1 - 0.015 15.1 0.4 0.041 13.7 0.3 1.7 1 0 0 1 1 1 0 ENTH domain DSHCT PF08148.7 AFZ81204.1 - 4.9e-53 179.0 0.0 1.1e-52 177.8 0.0 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 AFZ81204.1 - 4.7e-22 78.2 0.0 1.2e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ81204.1 - 2e-07 30.7 0.1 1.2e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ81204.1 - 2.7e-05 24.0 0.0 0.00011 22.0 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AhpC-TSA PF00578.16 AFZ81204.1 - 0.1 12.3 0.2 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family IBN_N PF03810.14 AFZ81205.1 - 0.00022 21.1 3.8 0.0017 18.2 0.1 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain RVT_1 PF00078.22 AFZ81205.1 - 0.0089 15.4 0.0 0.023 14.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.27 AFZ81206.1 - 3.3e-15 55.3 15.4 1.4e-08 34.3 0.1 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ_3 PF13570.1 AFZ81206.1 - 0.0031 17.7 2.1 16 5.9 0.3 4.4 3 1 1 4 4 4 2 PQQ-like domain zf-tcix PF14952.1 AFZ81206.1 - 0.02 14.2 2.2 0.02 14.2 1.6 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding DUF974 PF06159.8 AFZ81207.1 - 3.6e-06 26.6 0.3 9.1e-06 25.2 0.1 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF974) Transglut_C PF00927.17 AFZ81207.1 - 0.039 14.0 0.1 0.75 9.8 0.0 2.4 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain A2M PF00207.17 AFZ81207.1 - 0.086 12.4 0.0 4 7.0 0.0 2.6 2 0 0 2 2 2 0 Alpha-2-macroglobulin family Prp19_bind PF06991.6 AFZ81208.1 - 7.2e-63 212.4 32.7 7.2e-63 212.4 22.7 2.0 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain TMEM237 PF15383.1 AFZ81208.1 - 2.2 7.3 5.4 4.5 6.3 3.8 1.5 1 0 0 1 1 1 0 Transmembrane protein 237 DUF4613 PF15390.1 AFZ81208.1 - 4.2 5.4 14.3 5.5 5.0 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Y2_Tnp PF04986.8 AFZ81208.1 - 4.6 6.9 7.2 3.4 7.3 3.0 2.2 2 1 0 2 2 2 0 Putative transposase DUF2362 PF10154.4 AFZ81209.1 - 3.5e-08 32.5 6.0 4.4e-08 32.2 0.3 3.0 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2362) LSM PF01423.17 AFZ81210.1 - 8.4e-14 50.8 0.2 1.2e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AFZ81210.1 - 0.036 13.9 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain RINGv PF12906.2 AFZ81211.1 - 5.1e-13 48.8 8.8 1.2e-12 47.6 6.1 1.7 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.21 AFZ81211.1 - 6.4e-12 45.4 0.2 2.1e-10 40.5 0.1 2.7 2 0 0 2 2 2 1 FHA domain zf-RING_2 PF13639.1 AFZ81211.1 - 0.028 14.2 7.3 0.064 13.0 5.1 1.7 1 0 0 1 1 1 0 Ring finger domain FAST_1 PF06743.10 AFZ81212.1 - 0.00087 18.9 3.3 1.2 8.9 0.1 3.9 2 1 1 3 3 3 3 FAST kinase-like protein, subdomain 1 tRNA_lig_CPD PF08302.6 AFZ81214.1 - 3.2e-05 23.2 1.7 0.013 14.6 0.1 2.2 2 0 0 2 2 2 2 Fungal tRNA ligase phosphodiesterase domain DUF1638 PF07796.6 AFZ81214.1 - 0.0035 16.9 0.5 0.0065 16.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1638) LigT_PEase PF02834.11 AFZ81214.1 - 0.0082 16.0 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 2 LigT like Phosphoesterase FtsJ PF01728.14 AFZ81215.1 - 5e-54 183.0 0.0 6e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 AFZ81215.1 - 0.00018 21.1 0.1 0.004 16.7 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AFZ81215.1 - 0.084 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Gar1 PF04410.9 AFZ81216.1 - 3.8e-40 136.8 0.4 5.2e-40 136.4 0.2 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region HORMA PF02301.13 AFZ81218.1 - 5.5e-51 173.0 0.0 6.5e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 HORMA domain PRP3 PF08572.5 AFZ81219.1 - 4.5e-50 170.0 16.5 4.5e-50 170.0 11.5 2.1 2 1 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 AFZ81219.1 - 1.3e-28 99.2 0.1 1.3e-28 99.2 0.1 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1115) Methyltransf_32 PF13679.1 AFZ81219.1 - 3.2 7.4 7.1 0.47 10.1 0.1 2.8 2 1 0 2 2 2 0 Methyltransferase domain UCR_hinge PF02320.11 AFZ81220.1 - 2e-17 62.8 4.0 2.6e-17 62.5 2.8 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 AFZ81220.1 - 1.6 8.6 5.6 3.6 7.5 3.9 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Toxin_13 PF07822.6 AFZ81220.1 - 8.5 6.3 8.3 25 4.8 5.7 1.8 1 1 0 1 1 1 0 Neurotoxin B-IV-like protein RAP PF08373.5 AFZ81222.1 - 5.3e-07 29.3 0.1 1.5e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 RAP domain Med14 PF08638.6 AFZ81222.1 - 0.18 10.9 4.7 1.3 8.2 0.1 2.8 3 0 0 3 3 3 0 Mediator complex subunit MED14 Kelch_1 PF01344.20 AFZ81224.1 - 1e-39 133.7 11.7 9.2e-09 34.7 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 AFZ81224.1 - 3.6e-38 129.0 17.6 6.3e-09 35.4 0.0 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 AFZ81224.1 - 1.4e-35 120.6 15.4 3.7e-09 36.3 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 AFZ81224.1 - 1.8e-33 113.9 21.3 4.6e-09 36.1 0.0 7.5 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.1 AFZ81224.1 - 7e-31 105.1 17.2 1.4e-07 31.3 0.3 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 AFZ81224.1 - 1.2e-27 94.6 15.2 1.8e-07 30.6 0.2 6.5 6 0 0 6 6 6 6 Kelch motif BTB PF00651.26 AFZ81224.1 - 6.6e-19 67.9 0.3 3.9e-18 65.4 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 AFZ81224.1 - 0.067 13.0 0.1 0.7 9.7 0.0 2.3 2 0 0 2 2 2 0 BTB And C-terminal Kelch VIT1 PF01988.14 AFZ81225.1 - 3.4e-47 160.6 0.6 4.2e-47 160.3 0.4 1.0 1 0 0 1 1 1 1 VIT family DUF4131 PF13567.1 AFZ81225.1 - 0.0012 18.3 0.4 0.49 9.7 0.8 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) ATE_N PF04376.8 AFZ81225.1 - 0.11 12.3 0.1 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus RNA_pol_Rpb2_6 PF00562.23 AFZ81227.1 - 1.9e-118 395.5 0.0 2.7e-118 395.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AFZ81227.1 - 1.5e-61 206.8 0.0 2.5e-61 206.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 AFZ81227.1 - 8.5e-47 159.0 0.0 1.3e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 AFZ81227.1 - 4.6e-32 110.1 0.1 9.8e-32 109.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 AFZ81227.1 - 8.9e-26 89.4 0.0 2e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 AFZ81227.1 - 1.9e-23 81.9 0.1 4e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 AFZ81227.1 - 1.7e-19 69.5 1.6 1.7e-19 69.5 1.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Ycf1 PF05758.7 AFZ81228.1 - 0.049 11.3 5.1 0.061 11.0 3.5 1.2 1 0 0 1 1 1 0 Ycf1 MRP-L47 PF06984.8 AFZ81229.1 - 3e-22 78.3 0.2 3e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Seryl_tRNA_N PF02403.17 AFZ81229.1 - 0.063 13.2 4.9 0.1 12.6 3.4 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain MACPF PF01823.14 AFZ81230.1 - 4.3e-33 114.7 0.1 6.5e-33 114.2 0.1 1.2 1 0 0 1 1 1 1 MAC/Perforin domain TFIID_20kDa PF03847.8 AFZ81230.1 - 0.096 12.9 1.0 24 5.2 0.0 2.9 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A MACPF PF01823.14 AFZ81232.1 - 1.2e-37 129.6 0.9 2.2e-37 128.8 0.6 1.4 1 0 0 1 1 1 1 MAC/Perforin domain RNA_pol_Rpb2_6 PF00562.23 AFZ81233.1 - 1.4e-118 396.0 0.8 1.9e-118 395.5 0.6 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AFZ81233.1 - 3.1e-30 104.6 0.2 4.7e-30 104.0 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 AFZ81233.1 - 6.7e-21 73.8 0.0 1.4e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 AFZ81233.1 - 1.2e-17 63.9 0.0 3.5e-17 62.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 AFZ81233.1 - 0.00023 21.0 0.0 0.00074 19.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain zf-Mss51 PF13824.1 AFZ81233.1 - 0.23 11.3 2.3 19 5.2 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF1556 PF07590.6 AFZ81234.1 - 0.15 12.2 0.1 0.3 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) PLDc_2 PF13091.1 AFZ81236.1 - 5.3e-29 100.5 0.1 1.6e-14 53.7 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 AFZ81236.1 - 3.2e-11 42.6 2.5 7.2e-05 22.4 0.4 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif SRP54 PF00448.17 AFZ81236.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain zf-DHHC PF01529.15 AFZ81237.1 - 2.8e-35 121.2 11.8 2.8e-35 121.2 8.2 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase Slu7 PF11708.3 AFZ81238.1 - 1.7e-63 214.5 7.5 2.2e-63 214.1 5.2 1.1 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 AFZ81238.1 - 0.018 14.6 0.1 0.045 13.4 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF386 PF04074.7 AFZ81238.1 - 0.085 12.3 0.6 0.15 11.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF386) Ribosomal_L19 PF01245.15 AFZ81239.1 - 7.8e-15 54.6 0.0 7.8e-15 54.6 0.0 2.7 3 0 0 3 3 3 1 Ribosomal protein L19 TPR_11 PF13414.1 AFZ81240.1 - 6.6e-22 76.9 1.3 5.9e-06 25.8 0.0 5.9 4 2 1 5 5 5 5 TPR repeat TPR_19 PF14559.1 AFZ81240.1 - 4e-14 52.6 0.1 7.9e-06 26.1 0.0 5.6 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 AFZ81240.1 - 8.4e-14 50.3 0.5 0.024 14.5 0.0 6.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 AFZ81240.1 - 1e-12 47.1 0.7 0.049 13.8 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 AFZ81240.1 - 4.7e-10 39.1 0.0 0.22 12.2 0.0 6.0 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 AFZ81240.1 - 2.7e-09 36.8 1.9 0.00043 20.1 0.0 6.4 5 3 2 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 AFZ81240.1 - 3.3e-09 35.9 2.9 0.016 14.7 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 AFZ81240.1 - 4.3e-09 36.7 0.0 0.042 14.5 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ81240.1 - 9.3e-07 28.1 8.8 0.065 13.0 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 AFZ81240.1 - 5.9e-06 26.4 0.1 0.34 11.4 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 AFZ81240.1 - 0.00027 20.4 0.0 50 4.0 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 AFZ81240.1 - 0.00031 20.5 0.0 2.7 7.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 AFZ81240.1 - 0.017 15.2 0.5 0.017 15.2 0.3 5.8 6 1 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 AFZ81240.1 - 0.14 11.9 3.2 12 5.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Histone PF00125.19 AFZ81241.1 - 2.1e-24 85.4 0.0 2.8e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AFZ81241.1 - 0.00049 20.0 0.0 0.00082 19.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AFZ81242.1 - 1.5e-33 114.7 0.4 2.7e-33 113.9 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AFZ81242.1 - 0.00024 21.2 0.0 0.00037 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AFZ81242.1 - 0.0055 16.7 1.0 0.0097 15.9 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 AFZ81242.1 - 0.12 12.1 0.1 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PTH2 PF01981.11 AFZ81243.1 - 4.4e-07 29.5 0.0 6.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PWI PF01480.12 AFZ81244.1 - 8.1e-12 45.0 0.2 3.2e-11 43.1 0.1 2.1 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.17 AFZ81244.1 - 8e-09 35.0 0.0 2.2e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ81244.1 - 1.2e-05 25.1 0.0 4.5e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Colicin-DNase PF12639.2 AFZ81244.1 - 0.012 15.8 1.4 0.029 14.6 1.0 1.6 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin MTTB PF06253.6 AFZ81244.1 - 0.11 10.2 0.2 0.16 9.7 0.1 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Statherin PF03875.8 AFZ81244.1 - 5.4 6.9 6.8 6.6 6.6 0.3 2.8 2 0 0 2 2 2 0 Statherin Relaxase PF03432.9 AFZ81245.1 - 0.042 13.2 6.0 0.14 11.5 3.0 2.1 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain RRM_1 PF00076.17 AFZ81246.1 - 4.4e-17 61.4 0.0 6.6e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ81246.1 - 1.1e-13 50.8 0.0 1.8e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ81246.1 - 9.8e-07 28.5 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L22e PF01776.12 AFZ81247.1 - 1e-46 157.5 2.1 1.2e-46 157.2 1.5 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Tox-PLDMTX PF15645.1 AFZ81247.1 - 0.0017 18.4 0.1 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 Dermonecrotoxin of the Papain-like fold EF-hand_like PF09279.6 AFZ81247.1 - 0.012 15.6 0.1 0.15 12.0 0.1 2.1 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like RPN7 PF10602.4 AFZ81248.1 - 6.8e-50 168.8 0.1 1.4e-49 167.8 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 AFZ81248.1 - 6.2e-15 55.4 0.2 2.3e-14 53.5 0.1 1.9 1 0 0 1 1 1 1 PCI domain TPR_11 PF13414.1 AFZ81248.1 - 0.014 14.9 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.23 AFZ81248.1 - 0.031 13.8 0.3 0.07 12.7 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 AFZ81248.1 - 0.035 13.9 0.0 0.099 12.4 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ81248.1 - 0.063 13.0 0.5 0.4 10.5 0.3 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 AFZ81248.1 - 0.11 12.5 0.1 0.34 10.9 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.20 AFZ81249.1 - 4.8e-44 150.4 0.0 6.5e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ81249.1 - 1.1e-15 57.4 0.0 1.7e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AFZ81249.1 - 7e-06 25.2 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AFZ81249.1 - 0.00038 20.2 0.0 0.0016 18.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AFZ81249.1 - 0.017 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase EF-hand_6 PF13405.1 AFZ81250.1 - 1.6e-09 36.8 7.8 5.2e-06 25.9 0.5 4.2 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 AFZ81250.1 - 3.8e-08 32.0 10.7 4.5e-06 25.5 0.3 4.1 3 1 1 4 4 4 2 EF hand EF-hand_7 PF13499.1 AFZ81250.1 - 1.4e-07 31.4 5.4 2e-06 27.8 1.1 2.9 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 AFZ81250.1 - 2.1e-05 24.0 9.8 0.044 13.4 0.1 4.1 2 2 2 4 4 4 2 EF-hand domain pair Caleosin PF05042.8 AFZ81250.1 - 0.0055 16.2 1.5 1.9 7.9 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein ComFB PF10719.4 AFZ81250.1 - 0.0061 16.2 0.0 0.06 13.0 0.0 2.0 2 0 0 2 2 2 1 Late competence development protein ComFB UPF0158 PF03682.8 AFZ81250.1 - 0.082 12.5 0.6 0.12 12.0 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) Lip_prot_lig_C PF10437.4 AFZ81250.1 - 0.082 12.5 0.4 0.67 9.6 0.1 2.2 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus EF-hand_5 PF13202.1 AFZ81250.1 - 0.094 12.0 4.2 0.55 9.6 0.3 3.6 3 0 0 3 3 3 0 EF hand Ribosomal_S4e PF00900.15 AFZ81251.1 - 1.7e-28 98.1 0.0 4.2e-28 96.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 AFZ81251.1 - 3.3e-19 68.4 6.1 6.9e-19 67.4 4.2 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 AFZ81251.1 - 5.8e-06 25.8 1.4 5.8e-06 25.8 0.9 2.8 3 0 0 3 3 3 1 KOW motif S4 PF01479.20 AFZ81251.1 - 1.1e-05 24.7 0.1 2.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 S4 domain Herpes_gI PF01688.12 AFZ81251.1 - 0.032 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I MRP-S32 PF10210.4 AFZ81251.1 - 0.066 13.5 0.0 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 EF-hand_1 PF00036.27 AFZ81252.1 - 7.8e-26 87.3 12.8 2.8e-06 26.2 0.1 5.4 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 AFZ81252.1 - 1.3e-25 89.3 6.9 4.8e-10 39.4 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 AFZ81252.1 - 1.5e-22 77.8 13.5 3.5e-08 32.4 0.0 5.3 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 AFZ81252.1 - 2.1e-20 70.6 10.6 7.5e-06 25.4 0.0 5.4 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 AFZ81252.1 - 7.5e-11 41.4 8.6 5.7e-05 22.6 0.0 5.3 5 0 0 5 5 5 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 AFZ81252.1 - 1.9e-07 31.1 1.6 0.3 11.1 0.0 3.2 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region DUF1007 PF06226.8 AFZ81252.1 - 0.0052 16.5 0.5 0.59 9.8 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1007) YkyA PF10368.4 AFZ81252.1 - 0.013 14.8 0.9 0.019 14.2 0.6 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein EF-hand_10 PF14788.1 AFZ81252.1 - 0.17 11.6 0.9 27 4.5 0.0 2.9 3 0 0 3 3 3 0 EF hand ABC_ATPase PF09818.4 AFZ81254.1 - 7.9e-163 542.1 0.0 1e-162 541.8 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.1 AFZ81254.1 - 0.0027 18.0 7.1 0.003 17.9 2.2 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AFZ81254.1 - 0.0057 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF1726 PF08351.6 AFZ81255.1 - 0.083 12.5 0.3 0.099 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) DUF3340 PF11818.3 AFZ81255.1 - 0.71 9.8 4.1 0.69 9.8 2.8 1.1 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DEAD PF00270.24 AFZ81256.1 - 2.7e-17 62.7 0.0 7e-11 41.9 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ81256.1 - 6.5e-13 48.3 0.0 2.1e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ81256.1 - 0.0045 16.8 0.0 0.23 11.2 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ribosomal_S15 PF00312.17 AFZ81258.1 - 1.2e-16 60.2 1.9 1.2e-16 60.2 1.3 2.5 3 0 0 3 3 3 1 Ribosomal protein S15 FliJ PF02050.11 AFZ81258.1 - 0.02 14.9 2.7 0.025 14.6 0.2 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein Gpi16 PF04113.9 AFZ81259.1 - 2.1e-23 82.1 2.8 8.1e-13 47.2 0.0 3.0 2 1 1 3 3 3 3 Gpi16 subunit, GPI transamidase component RNA_pol_Rpb1_5 PF04998.12 AFZ81260.1 - 1.1e-92 310.2 0.3 2.2e-92 309.2 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 AFZ81260.1 - 1.7e-75 254.3 3.6 2.7e-75 253.7 2.5 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 AFZ81260.1 - 1.4e-65 220.2 0.0 5.3e-65 218.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 AFZ81260.1 - 3.1e-32 111.4 0.0 1.3e-31 109.4 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 AFZ81260.1 - 3.9e-30 103.7 0.0 1.2e-29 102.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 HSP90 PF00183.13 AFZ81262.1 - 1.3e-128 429.7 10.0 8.3e-121 403.9 2.7 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 AFZ81262.1 - 2.2e-11 43.5 0.1 5.4e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AFZ81262.1 - 2e-07 30.6 0.0 4.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.20 AFZ81263.1 - 2.2e-40 138.4 0.0 4.8e-20 71.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ81263.1 - 7.7e-13 48.1 0.0 5.1e-05 22.4 0.0 3.3 2 1 0 2 2 2 2 Protein tyrosine kinase Ras PF00071.17 AFZ81264.1 - 9.9e-59 197.3 0.1 1.1e-58 197.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AFZ81264.1 - 5e-18 65.7 0.0 7.7e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AFZ81264.1 - 2e-16 59.7 0.0 2.5e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AFZ81264.1 - 0.00013 21.1 0.0 0.00021 20.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 AFZ81264.1 - 0.00024 20.3 0.0 0.029 13.6 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 AFZ81264.1 - 0.00029 20.7 0.0 0.0004 20.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AFZ81264.1 - 0.001 18.5 0.1 0.0026 17.2 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AFZ81264.1 - 0.0013 17.9 0.1 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 AFZ81264.1 - 0.0071 15.5 0.1 0.018 14.2 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 AFZ81264.1 - 0.0095 16.0 0.0 0.015 15.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AFZ81264.1 - 0.049 13.6 0.0 0.057 13.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_M29 PF02073.10 AFZ81264.1 - 0.071 11.8 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) ABC_tran PF00005.22 AFZ81264.1 - 0.076 13.3 0.0 0.12 12.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter GATA PF00320.22 AFZ81265.1 - 9e-08 31.3 2.2 1.8e-07 30.4 1.5 1.5 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.13 AFZ81265.1 - 0.0042 16.8 0.5 0.0042 16.8 0.4 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf OTU PF02338.14 AFZ81266.1 - 0.0038 17.8 0.0 1.5 9.3 0.0 2.4 1 1 1 2 2 2 2 OTU-like cysteine protease OTU PF02338.14 AFZ81267.1 - 0.00067 20.2 0.5 0.12 12.9 0.3 2.8 1 1 0 1 1 1 1 OTU-like cysteine protease Sec1 PF00995.18 AFZ81268.1 - 2e-49 168.7 5.0 2.7e-49 168.2 3.5 1.1 1 0 0 1 1 1 1 Sec1 family D123 PF07065.9 AFZ81269.1 - 3.3e-28 98.6 11.2 4e-28 98.3 5.4 2.4 2 1 0 2 2 2 1 D123 Fe-S_biosyn PF01521.15 AFZ81270.1 - 2.4e-11 43.5 0.0 3.1e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3390 PF11870.3 AFZ81271.1 - 0.018 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) OPA3 PF07047.7 AFZ81272.1 - 6.2e-09 35.7 0.0 1.1e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) AAA PF00004.24 AFZ81274.1 - 4.3e-09 36.6 0.0 1.2e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AFZ81274.1 - 4.7e-08 32.1 0.1 3.4e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 AFZ81274.1 - 9.1e-07 29.7 0.5 4.3e-06 27.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AFZ81274.1 - 2e-06 28.1 0.6 8.5e-05 22.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AFZ81274.1 - 0.00017 21.4 0.0 0.00085 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AFZ81274.1 - 0.00018 21.3 0.1 0.00052 19.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 AFZ81274.1 - 0.0003 20.5 0.0 0.00087 19.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AFZ81274.1 - 0.00038 20.5 0.0 0.00091 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 AFZ81274.1 - 0.0004 19.5 0.0 0.00083 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 AFZ81274.1 - 0.00042 20.0 0.1 0.0013 18.4 0.0 1.7 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 AFZ81274.1 - 0.00051 19.1 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 AFZ81274.1 - 0.0006 19.8 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AFZ81274.1 - 0.00061 19.9 0.0 0.0016 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AFZ81274.1 - 0.0031 16.6 0.0 0.0059 15.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 AFZ81274.1 - 0.01 15.0 0.0 0.58 9.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 AFZ81274.1 - 0.03 14.6 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 AFZ81274.1 - 0.035 13.5 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 AFZ81274.1 - 0.045 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 NTPase PAP2_C PF14360.1 AFZ81275.1 - 4.5e-15 55.6 16.0 4.5e-15 55.6 11.1 3.0 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 AFZ81275.1 - 0.00018 21.1 9.6 0.00018 21.1 6.6 2.0 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 AFZ81275.1 - 0.0036 16.8 11.2 0.0078 15.7 7.8 1.6 1 0 0 1 1 1 1 PAP2 superfamily Mito_carr PF00153.22 AFZ81276.1 - 4.7e-07 29.4 0.3 0.00033 20.3 0.1 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein PA14 PF07691.7 AFZ81278.1 - 2.3e-20 72.7 0.0 1e-19 70.6 0.0 2.1 2 0 0 2 2 2 1 PA14 domain LCCL PF03815.14 AFZ81278.1 - 0.00085 19.2 0.2 0.0032 17.4 0.1 2.0 1 0 0 1 1 1 1 LCCL domain Viral_P18 PF04521.8 AFZ81278.1 - 0.0043 16.4 4.6 0.0094 15.3 3.2 1.5 1 0 0 1 1 1 1 ssRNA positive strand viral 18kD cysteine rich protein TMF_DNA_bd PF12329.3 AFZ81278.1 - 5.2 6.9 11.6 1.4 8.7 4.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ITI_HC_C PF06668.7 AFZ81279.1 - 0.01 15.2 0.1 0.023 14.1 0.1 1.6 1 1 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus GCV_T_C PF08669.6 AFZ81280.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain DUF2637 PF10935.3 AFZ81280.1 - 3.6 7.5 14.0 0.043 13.7 1.6 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF2637) ABC_tran PF00005.22 AFZ81281.1 - 2.4e-31 108.8 0.0 1.7e-17 63.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AFZ81281.1 - 2.9e-06 27.4 6.5 0.022 14.7 0.2 4.1 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.1 AFZ81281.1 - 1.3e-05 25.2 0.1 0.02 14.8 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 AFZ81281.1 - 2.5e-05 24.6 4.4 0.049 13.9 0.2 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AFZ81281.1 - 5.4e-05 22.6 1.3 0.086 12.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 AFZ81281.1 - 0.00011 21.7 0.0 0.043 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AFZ81281.1 - 0.00033 21.4 0.0 0.21 12.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 AFZ81281.1 - 0.00047 19.7 0.2 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AFZ81281.1 - 0.00061 20.0 0.2 0.35 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AFZ81281.1 - 0.0019 17.1 0.6 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein MobB PF03205.9 AFZ81281.1 - 0.0023 17.6 1.0 0.7 9.5 0.0 3.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 AFZ81281.1 - 0.0027 16.5 0.5 0.0073 15.1 0.0 1.8 2 0 0 2 2 2 1 ArgK protein DUF258 PF03193.11 AFZ81281.1 - 0.0031 16.7 0.7 0.24 10.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF87 PF01935.12 AFZ81281.1 - 0.0032 17.3 2.0 0.082 12.7 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 AFZ81281.1 - 0.0035 16.8 0.3 0.74 9.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 AFZ81281.1 - 0.0041 16.2 0.2 2.5 7.1 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin UPF0079 PF02367.12 AFZ81281.1 - 0.0063 16.1 0.7 0.16 11.5 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 AFZ81281.1 - 0.0066 16.1 0.5 2.2 7.8 0.1 2.6 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 AFZ81281.1 - 0.0076 16.7 0.0 4.2 7.8 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 AFZ81281.1 - 0.0091 16.1 0.1 3.6 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AFZ81281.1 - 0.01 15.5 1.8 4 7.2 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain SMC_N PF02463.14 AFZ81281.1 - 0.013 14.6 0.9 0.18 11.0 0.1 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.18 AFZ81281.1 - 0.017 14.9 0.4 4.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_15 PF13175.1 AFZ81281.1 - 0.018 14.0 2.1 7.8 5.4 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain SbcCD_C PF13558.1 AFZ81281.1 - 0.036 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 AFZ81281.1 - 0.038 13.9 0.1 0.32 10.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.14 AFZ81281.1 - 0.079 12.4 1.9 8.8 5.7 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 AFZ81281.1 - 0.11 11.1 0.3 5 5.6 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DnaB_C PF03796.10 AFZ81281.1 - 0.13 11.0 0.0 4.6 6.0 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_10 PF12846.2 AFZ81281.1 - 0.13 11.6 0.3 9 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 AFZ81281.1 - 0.16 11.8 0.1 7.3 6.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain NUDIX_2 PF13869.1 AFZ81282.1 - 6.7e-41 139.6 0.0 8.1e-41 139.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Acetyltransf_1 PF00583.19 AFZ81285.1 - 7.8e-15 54.6 0.1 1.3e-14 53.9 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AFZ81285.1 - 2.9e-08 33.7 0.2 4.1e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AFZ81285.1 - 4e-07 29.6 0.0 8.1e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 AFZ81285.1 - 9.2e-07 28.9 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AFZ81285.1 - 3e-05 24.0 0.2 4.1e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AFZ81285.1 - 0.00077 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 AFZ81285.1 - 0.031 13.8 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AFZ81285.1 - 0.04 13.8 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AFZ81285.1 - 0.1 12.4 0.0 0.3 11.0 0.0 1.7 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase TBCA PF02970.11 AFZ81286.1 - 5.4e-12 45.6 1.8 6.2e-12 45.4 1.2 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A YwqJ-deaminase PF14431.1 AFZ81286.1 - 0.1 12.4 0.0 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 YwqJ-like deaminase tRNA-synt_2d PF01409.15 AFZ81287.1 - 8.1e-79 264.2 0.0 1.2e-78 263.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 AFZ81287.1 - 7.7e-05 22.3 0.0 0.00014 21.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 AFZ81287.1 - 0.001 17.8 0.6 0.0035 16.1 0.0 2.1 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) Metallophos PF00149.23 AFZ81288.1 - 3.7e-23 81.9 4.6 5.6e-23 81.3 3.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mre11_DNA_bind PF04152.9 AFZ81288.1 - 2.5e-18 66.5 1.1 2.5e-18 66.5 0.7 2.2 2 1 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos_2 PF12850.2 AFZ81288.1 - 1.2e-07 31.7 0.0 3.2e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AT_hook PF02178.14 AFZ81288.1 - 0.023 14.3 2.4 0.051 13.2 1.7 1.6 1 0 0 1 1 1 0 AT hook motif TatD_DNase PF01026.16 AFZ81288.1 - 0.028 13.6 0.0 0.097 11.8 0.0 1.9 2 0 0 2 2 2 0 TatD related DNase Iso_dh PF00180.15 AFZ81289.1 - 2.2e-65 220.9 0.0 2.7e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Proteasome PF00227.21 AFZ81291.1 - 1e-35 122.7 0.0 4.1e-35 120.8 0.0 1.7 1 1 0 1 1 1 1 Proteasome subunit TMF_DNA_bd PF12329.3 AFZ81292.1 - 0.0012 18.5 2.5 0.0012 18.5 1.7 3.8 2 1 2 4 4 4 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 AFZ81292.1 - 0.014 15.2 10.8 0.014 15.2 7.5 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF641 PF04859.7 AFZ81292.1 - 0.53 10.0 12.8 1.3 8.7 1.8 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) IncA PF04156.9 AFZ81292.1 - 3.4 7.2 24.8 9 5.8 15.8 2.0 1 1 1 2 2 2 0 IncA protein SlyX PF04102.7 AFZ81292.1 - 5.8 7.3 15.0 9.4 6.6 0.4 3.6 1 1 2 3 3 3 0 SlyX Tmemb_14 PF03647.8 AFZ81293.1 - 0.0014 18.9 8.2 0.0026 18.1 5.6 1.6 1 1 0 1 1 1 1 Transmembrane proteins 14C HupE_UreJ_2 PF13795.1 AFZ81293.1 - 0.21 11.0 3.8 0.26 10.7 2.7 1.2 1 0 0 1 1 1 0 HupE / UreJ protein Trep_Strep PF09605.5 AFZ81293.1 - 0.47 10.1 7.2 0.76 9.4 5.0 1.4 1 1 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Oxidored_q2 PF00420.19 AFZ81293.1 - 0.82 9.3 8.7 5.2 6.7 3.1 2.2 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2628 PF10947.3 AFZ81293.1 - 2.7 7.8 7.3 15 5.3 5.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) COPI_assoc PF08507.5 AFZ81293.1 - 3.9 7.1 9.9 5.8 6.5 6.9 1.4 1 1 0 1 1 1 0 COPI associated protein PIG-L PF02585.12 AFZ81294.1 - 8.8e-17 61.8 0.0 1.4e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase SNF2_N PF00176.18 AFZ81295.1 - 2.5e-53 180.8 0.0 7.6e-53 179.2 0.0 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.24 AFZ81295.1 - 2.4e-21 75.1 75.7 1.3e-10 40.7 4.8 7.2 6 1 0 6 6 6 4 PHD-finger Helicase_C PF00271.26 AFZ81295.1 - 2.3e-13 49.7 0.0 6e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-PHD-like PF15446.1 AFZ81295.1 - 3.2e-06 26.5 38.1 0.0027 17.0 0.9 6.8 5 2 2 7 7 7 5 PHD/FYVE-zinc-finger like domain DEAD PF00270.24 AFZ81295.1 - 4.9e-06 26.1 0.0 0.00013 21.4 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase PHD_2 PF13831.1 AFZ81295.1 - 0.00025 20.3 1.9 0.00025 20.3 1.3 8.1 8 0 0 8 8 8 3 PHD-finger C1_1 PF00130.17 AFZ81295.1 - 0.0011 18.5 0.9 0.0011 18.5 0.6 7.9 6 1 1 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 AFZ81295.1 - 0.0017 18.0 2.2 0.0017 18.0 1.6 7.3 7 1 0 7 7 7 3 Prokaryotic RING finger family 1 GTP_EFTU PF00009.22 AFZ81296.1 - 7.5e-34 116.8 0.0 1.3e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AFZ81296.1 - 0.00022 21.1 0.1 0.00049 20.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 AFZ81296.1 - 0.011 14.8 0.1 0.03 13.3 0.0 1.7 2 0 0 2 2 2 0 Septin Miro PF08477.8 AFZ81296.1 - 0.024 15.1 0.0 0.07 13.6 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 AFZ81296.1 - 0.13 12.1 4.3 0.66 9.7 0.0 2.7 2 1 1 3 3 3 0 Dynamin family Nop52 PF05997.7 AFZ81297.1 - 4.8e-53 179.8 6.9 8.8e-53 178.9 4.8 1.4 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.3 AFZ81297.1 - 0.0028 17.4 1.2 0.015 14.9 0.1 2.6 2 1 1 3 3 3 1 Telomere-length maintenance and DNA damage repair NifU PF01106.12 AFZ81298.1 - 9.9e-21 73.3 0.2 1.4e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 NifU-like domain Ank_2 PF12796.2 AFZ81299.1 - 1.3e-65 217.7 8.3 2.2e-24 85.6 0.9 5.7 1 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 AFZ81299.1 - 1.3e-40 135.1 0.5 6.1e-08 32.0 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 AFZ81299.1 - 2.8e-32 110.4 5.0 5.3e-09 36.3 0.0 7.1 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 AFZ81299.1 - 2.6e-31 104.5 3.0 0.0001 22.2 0.0 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 AFZ81299.1 - 5.4e-25 86.8 0.2 4.5e-07 29.9 0.0 6.4 3 2 2 6 6 6 4 Ankyrin repeats (many copies) Kelch_4 PF13418.1 AFZ81300.1 - 1.2e-29 101.8 12.9 4.4e-08 32.7 0.0 7.2 6 2 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 AFZ81300.1 - 8.4e-28 95.8 13.5 1e-08 35.0 0.0 8.0 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 AFZ81300.1 - 8.7e-23 79.4 14.2 8.7e-11 41.5 0.1 6.5 4 2 2 6 6 6 5 Kelch motif Kelch_5 PF13854.1 AFZ81300.1 - 3.4e-20 71.5 5.3 4.8e-05 23.1 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 AFZ81300.1 - 1.6e-11 43.4 8.4 0.0015 18.1 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 AFZ81300.1 - 2.1e-10 39.9 15.2 0.00034 20.1 0.1 6.3 6 1 0 6 6 6 4 Kelch motif DUF4110 PF13422.1 AFZ81300.1 - 2.3e-08 33.7 1.8 3.8e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) PK PF00224.16 AFZ81301.1 - 2.4e-139 463.8 0.7 3.9e-139 463.0 0.5 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 AFZ81301.1 - 1.1e-28 99.1 0.4 2.9e-28 97.7 0.3 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 AFZ81301.1 - 0.00035 19.5 0.2 0.00076 18.4 0.1 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEPcase_2 PF14010.1 AFZ81301.1 - 0.067 11.4 0.4 0.14 10.4 0.1 1.6 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxylase NUDIX PF00293.23 AFZ81302.1 - 0.023 14.3 0.0 0.077 12.6 0.0 1.9 1 1 0 1 1 1 0 NUDIX domain MRP-L46 PF11788.3 AFZ81302.1 - 0.26 11.9 3.7 0.21 12.2 0.8 2.2 2 1 1 3 3 3 0 39S mitochondrial ribosomal protein L46 RNase_PH PF01138.16 AFZ81303.1 - 7.6e-11 42.4 0.4 1.6e-10 41.3 0.3 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AFZ81303.1 - 2.3e-05 24.2 0.1 4.9e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 AP2 PF00847.15 AFZ81304.1 - 5.8e-06 26.3 4.2 1.1e-05 25.5 2.9 1.5 1 0 0 1 1 1 1 AP2 domain UCR_UQCRX_QCR9 PF05365.7 AFZ81305.1 - 9.1e-08 31.6 0.1 1.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like RAP PF08373.5 AFZ81306.1 - 2.3e-09 36.9 0.8 6.6e-09 35.4 0.5 1.9 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.10 AFZ81307.1 - 0.00069 19.2 3.4 1.6 8.5 0.0 5.0 4 1 1 5 5 5 3 FAST kinase-like protein, subdomain 1 Fe-S_biosyn PF01521.15 AFZ81308.1 - 1.6e-12 47.3 0.1 2e-12 47.0 0.1 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis OrfB_Zn_ribbon PF07282.6 AFZ81308.1 - 0.052 13.2 0.1 0.087 12.5 0.1 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF3437 PF11919.3 AFZ81310.1 - 1.5e-21 75.8 0.1 7.8e-21 73.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) Cullin PF00888.17 AFZ81311.1 - 3.3e-38 131.6 12.3 3.8e-38 131.4 8.5 1.0 1 0 0 1 1 1 1 Cullin family ERp29 PF07749.7 AFZ81311.1 - 0.22 12.1 1.8 1.5 9.5 0.1 2.7 2 1 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain rve_2 PF13333.1 AFZ81311.1 - 0.23 11.5 3.6 0.67 10.0 0.6 3.2 4 0 0 4 4 4 0 Integrase core domain YolD PF08863.5 AFZ81311.1 - 2 8.3 6.1 0.87 9.4 0.3 2.9 2 1 1 3 3 3 0 YolD-like protein Cullin PF00888.17 AFZ81312.1 - 2.8e-13 49.2 3.8 3.3e-13 49.0 2.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin PF00888.17 AFZ81313.1 - 1.2e-15 57.1 0.2 1.3e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 AFZ81313.1 - 1.4e-05 24.8 0.1 3.6e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain EF1_GNE PF00736.14 AFZ81313.1 - 0.032 13.9 1.1 0.21 11.3 0.0 2.2 2 1 0 2 2 2 0 EF-1 guanine nucleotide exchange domain Mito_carr PF00153.22 AFZ81314.1 - 1.4e-30 104.8 0.7 5.4e-09 35.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1 PF00133.17 AFZ81315.1 - 9.5e-38 129.5 0.3 2.5e-21 75.3 0.1 3.7 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 AFZ81315.1 - 5.3e-21 74.7 0.3 9e-10 37.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 AFZ81315.1 - 2.1e-14 53.5 3.0 4.9e-14 52.3 2.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 AFZ81315.1 - 1.1e-09 37.8 0.0 2.8e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 AFZ81315.1 - 0.0027 16.4 0.1 0.038 12.6 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (K) DUF647 PF04884.9 AFZ81316.1 - 3.7e-29 101.6 1.5 9.1e-29 100.3 1.1 1.5 1 1 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Radical_SAM PF04055.16 AFZ81317.1 - 9.9e-23 81.1 0.0 2.1e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 AFZ81317.1 - 3.7e-19 68.3 0.0 1.3e-18 66.6 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 AFZ81317.1 - 5e-06 26.2 0.0 9.6e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 TRAM domain S1 PF00575.18 AFZ81318.1 - 1.8e-12 47.1 0.0 1.8e-11 43.9 0.0 2.5 3 0 0 3 3 3 1 S1 RNA binding domain DUF4074 PF13293.1 AFZ81318.1 - 0.038 14.2 0.1 0.087 13.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4074) S1 PF00575.18 AFZ81319.1 - 0.034 14.2 0.1 0.093 12.8 0.1 1.7 1 0 0 1 1 1 0 S1 RNA binding domain CAF1 PF04857.15 AFZ81323.1 - 4.4e-62 209.7 0.4 6.7e-62 209.1 0.3 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease HTH_11 PF08279.7 AFZ81323.1 - 0.11 12.1 0.1 12 5.6 0.0 2.3 2 0 0 2 2 2 0 HTH domain DUF2009 PF09418.5 AFZ81325.1 - 2.5e-191 636.4 3.8 2.2e-123 412.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2009) Cyclin_N PF00134.18 AFZ81326.1 - 3.1e-07 29.9 0.7 7.6e-07 28.7 0.5 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3755 PF12579.3 AFZ81326.1 - 0.15 11.4 0.4 0.48 9.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) RasGEF PF00617.14 AFZ81327.1 - 0.057 13.1 3.6 0.089 12.5 0.5 2.6 2 1 0 3 3 3 0 RasGEF domain PAH PF02671.16 AFZ81327.1 - 0.092 12.3 0.5 1.1 8.9 0.0 2.8 2 0 0 2 2 2 0 Paired amphipathic helix repeat ParB PF08775.5 AFZ81327.1 - 0.13 12.5 2.4 0.57 10.4 0.1 3.1 2 1 1 3 3 3 0 ParB family Ras PF00071.17 AFZ81328.1 - 6e-42 142.7 0.2 8.6e-42 142.2 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AFZ81328.1 - 4.9e-16 59.2 0.1 1.4e-15 57.8 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AFZ81328.1 - 1.2e-13 50.6 0.1 1.1e-12 47.5 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AFZ81328.1 - 8.7e-09 35.0 0.1 1.3e-08 34.4 0.1 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AFZ81328.1 - 4.2e-05 23.4 0.1 0.00011 22.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 AFZ81328.1 - 0.00031 19.9 0.5 0.0022 17.1 0.2 2.2 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 AFZ81328.1 - 0.0017 17.9 0.2 0.047 13.2 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.5 AFZ81328.1 - 0.004 16.3 0.2 0.086 12.0 0.0 2.4 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit DUF2341 PF10102.4 AFZ81328.1 - 0.035 14.2 0.4 2 8.6 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2341) FlbD PF06289.6 AFZ81328.1 - 0.077 12.3 0.3 0.2 11.0 0.1 1.7 1 1 1 2 2 2 0 Flagellar protein (FlbD) Dynamin_N PF00350.18 AFZ81328.1 - 0.24 11.1 1.7 3 7.6 1.2 2.5 1 1 0 1 1 1 0 Dynamin family HAP2-GCS1 PF10699.4 AFZ81329.1 - 5.4e-15 55.0 0.0 1.3e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Male gamete fusion factor zf-HC5HC2H_2 PF13832.1 AFZ81330.1 - 1.3e-39 134.5 27.8 1.3e-19 70.1 2.1 6.1 6 0 0 6 6 6 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 AFZ81330.1 - 6.1e-13 48.7 27.2 8.4e-07 29.0 7.3 8.4 5 3 3 9 9 9 3 PHD-like zinc-binding domain PHD_2 PF13831.1 AFZ81330.1 - 7.2e-08 31.6 48.9 9.4e-06 24.8 3.9 7.0 6 0 0 6 6 6 4 PHD-finger PHD PF00628.24 AFZ81330.1 - 0.0017 18.0 11.1 0.0017 18.0 7.7 9.4 9 1 0 10 10 10 3 PHD-finger C1_1 PF00130.17 AFZ81330.1 - 0.0032 17.1 1.7 0.0032 17.1 1.2 7.5 8 0 0 8 8 8 4 Phorbol esters/diacylglycerol binding domain (C1 domain) tRNA-synt_1 PF00133.17 AFZ81331.1 - 2.7e-68 230.4 0.2 2.2e-65 220.8 0.1 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 AFZ81331.1 - 2.7e-11 42.7 0.1 2.9e-05 22.9 0.0 3.8 4 0 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1d PF00750.14 AFZ81331.1 - 3.3e-05 22.8 0.1 0.043 12.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 AFZ81331.1 - 0.0014 17.7 0.0 0.12 11.4 0.0 2.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 AFZ81331.1 - 0.0034 16.7 0.1 0.045 13.0 0.0 2.3 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1b PF00579.20 AFZ81331.1 - 0.006 15.7 0.9 0.0089 15.1 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) PI3_PI4_kinase PF00454.22 AFZ81332.1 - 3.3e-32 111.8 0.0 5.6e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4282 PF14110.1 AFZ81333.1 - 0.0084 16.2 7.2 0.013 15.7 5.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4282) DUF204 PF02659.10 AFZ81333.1 - 4.7 7.4 7.8 0.37 10.9 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF Sybindin PF04099.7 AFZ81335.1 - 5.5e-36 123.4 0.2 6.1e-36 123.2 0.2 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 AFZ81335.1 - 0.0019 18.0 0.1 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region CBM_14 PF01607.19 AFZ81335.1 - 0.57 10.1 2.4 0.88 9.5 0.1 2.2 3 0 0 3 3 3 0 Chitin binding Peritrophin-A domain PuR_N PF09182.5 AFZ81336.1 - 0.05 13.2 0.1 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal Methyltransf_26 PF13659.1 AFZ81338.1 - 1.7e-09 37.7 0.0 2.4e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AFZ81338.1 - 1.2e-08 34.5 0.0 1.1e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain DUF938 PF06080.7 AFZ81338.1 - 0.00017 21.2 0.0 0.00037 20.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF938) Methyltransf_31 PF13847.1 AFZ81338.1 - 0.075 12.6 0.0 1.6 8.2 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 AFZ81338.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase SPOC PF07744.8 AFZ81339.1 - 8.6e-14 52.0 0.0 1.5e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 SPOC domain HABP4_PAI-RBP1 PF04774.10 AFZ81340.1 - 2.3e-09 37.6 3.3 2.3e-09 37.6 2.3 2.9 3 1 0 3 3 3 1 Hyaluronan / mRNA binding family DEAD PF00270.24 AFZ81341.1 - 5.5e-43 146.3 0.0 9.9e-43 145.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ81341.1 - 7.8e-26 89.7 0.0 1.6e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ81341.1 - 0.00017 21.4 0.0 0.0004 20.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AFZ81341.1 - 0.022 14.4 0.0 0.53 10.0 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Peptidase_M17 PF00883.16 AFZ81343.1 - 2.4e-111 371.5 0.1 3.1e-111 371.1 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 AFZ81343.1 - 0.0017 18.1 0.0 0.0046 16.7 0.0 1.7 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain CSTF2_hinge PF14327.1 AFZ81344.1 - 7.3e-17 61.2 0.7 7.3e-17 61.2 0.5 1.8 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 SGS PF05002.10 AFZ81345.1 - 7.8e-17 60.8 1.8 1.5e-16 59.9 1.3 1.6 1 1 0 1 1 1 1 SGS domain CS PF04969.11 AFZ81345.1 - 0.0018 18.8 5.2 0.0021 18.5 1.9 2.2 1 1 1 2 2 2 1 CS domain CPW_WPC PF09717.5 AFZ81346.1 - 2.4e-18 66.4 7.2 2.1e-15 57.0 0.9 2.2 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) FH2 PF02181.18 AFZ81347.1 - 2.2e-66 224.2 6.6 3.3e-66 223.6 1.9 2.6 2 1 0 2 2 2 1 Formin Homology 2 Domain TPR_12 PF13424.1 AFZ81347.1 - 9.8e-11 41.4 2.0 0.00014 21.7 0.0 3.8 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 AFZ81347.1 - 6.3e-05 22.7 0.4 0.99 9.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ81347.1 - 8e-05 22.1 4.7 0.22 11.3 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 AFZ81347.1 - 0.0026 17.3 4.2 0.013 15.1 0.2 3.5 4 0 0 4 4 4 1 TPR repeat Apc3 PF12895.2 AFZ81347.1 - 0.0048 16.9 5.0 3.3 7.9 0.4 4.1 3 2 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 AFZ81347.1 - 0.036 13.6 7.2 0.39 10.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 AFZ81347.1 - 0.37 10.8 3.6 45 4.2 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TH1 PF04858.8 AFZ81348.1 - 3.2e-13 48.7 2.7 2.4e-08 32.5 1.2 3.0 3 0 0 3 3 3 3 TH1 protein Spc42p PF11544.3 AFZ81349.1 - 0.0051 16.7 8.4 0.0051 16.7 5.8 2.8 2 1 1 3 3 3 1 Spindle pole body component Spc42p MtlR PF05068.7 AFZ81349.1 - 0.012 15.0 0.7 0.022 14.2 0.5 1.4 1 0 0 1 1 1 0 Mannitol repressor SlyX PF04102.7 AFZ81349.1 - 0.03 14.6 0.9 0.03 14.6 0.6 2.5 2 1 0 2 2 2 0 SlyX DUF3216 PF11505.3 AFZ81349.1 - 0.042 13.6 0.9 0.042 13.6 0.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3216) HALZ PF02183.13 AFZ81349.1 - 3 7.6 12.4 4.6 7.0 1.6 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper BTB_2 PF02214.17 AFZ81350.1 - 1.2e-14 54.2 0.2 4e-14 52.5 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain hSac2 PF12456.3 AFZ81350.1 - 0.029 13.7 0.2 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 Inositol phosphatase Mito_carr PF00153.22 AFZ81351.1 - 2.1e-29 101.0 0.5 1.8e-15 56.4 0.1 2.7 2 1 1 3 3 3 2 Mitochondrial carrier protein Mito_carr PF00153.22 AFZ81352.1 - 3e-05 23.6 0.0 3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Pkinase PF00069.20 AFZ81353.1 - 8.2e-72 241.4 0.2 1.1e-71 241.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ81353.1 - 6.9e-36 123.6 0.1 1.1e-35 122.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AFZ81353.1 - 4.3e-06 25.8 0.0 1.6e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like EcoRI PF02963.11 AFZ81353.1 - 0.0083 14.9 0.1 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease EcoRI DUF3148 PF11347.3 AFZ81353.1 - 0.022 14.3 0.0 6.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) Kdo PF06293.9 AFZ81353.1 - 0.029 13.4 0.1 0.044 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AFZ81353.1 - 0.13 11.9 0.1 1 9.0 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Memo PF01875.12 AFZ81354.1 - 2.8e-70 236.3 0.0 3.4e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Seadorna_VP6 PF07407.6 AFZ81354.1 - 0.014 14.2 0.1 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP6 protein LETM1 PF07766.8 AFZ81355.1 - 2.1e-63 213.8 11.9 2.1e-63 213.8 8.3 1.9 2 1 1 3 3 3 1 LETM1-like protein HTH_26 PF13443.1 AFZ81355.1 - 0.045 13.9 0.2 0.31 11.2 0.0 2.4 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain SAP PF02037.22 AFZ81355.1 - 0.13 11.8 9.4 3.7 7.1 0.2 4.2 3 0 0 3 3 3 0 SAP domain LON PF02190.11 AFZ81355.1 - 4.2 6.9 11.6 0.054 13.1 1.3 2.6 3 0 0 3 3 3 0 ATP-dependent protease La (LON) domain CRAL_TRIO PF00650.15 AFZ81356.1 - 1.3e-20 73.4 0.0 1.9e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AFZ81356.1 - 5.8e-06 26.3 1.6 8.6e-06 25.7 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AFZ81356.1 - 0.00033 20.5 0.0 0.00067 19.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Band_7 PF01145.20 AFZ81357.1 - 7.1e-08 32.5 0.2 1.1e-07 31.9 0.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Maf1 PF09174.5 AFZ81358.1 - 7.6e-34 117.1 6.6 1.2e-33 116.4 4.6 1.4 1 0 0 1 1 1 1 Maf1 regulator RRM_1 PF00076.17 AFZ81360.1 - 8e-07 28.5 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ81360.1 - 0.00019 21.3 0.2 0.00035 20.5 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 AFZ81360.1 - 0.039 13.9 0.0 0.044 13.8 0.0 1.1 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Arf PF00025.16 AFZ81361.1 - 1.7e-59 199.9 0.0 2e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 AFZ81361.1 - 5.6e-12 45.0 0.2 5.5e-09 35.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 AFZ81361.1 - 3.4e-10 40.4 0.0 4.7e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 AFZ81361.1 - 1.6e-09 37.2 0.0 2e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AFZ81361.1 - 2.2e-09 37.2 0.0 2.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 AFZ81361.1 - 3.5e-08 33.0 0.0 4.5e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 AFZ81361.1 - 1.8e-06 27.2 0.0 2.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AFZ81361.1 - 9.1e-06 25.2 0.0 0.00047 19.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 AFZ81361.1 - 0.0038 17.3 0.1 0.022 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 AFZ81361.1 - 0.0049 16.5 0.1 0.12 12.0 0.1 2.2 1 1 0 1 1 1 1 NACHT domain Dynamin_N PF00350.18 AFZ81361.1 - 0.018 14.8 0.0 1.8 8.3 0.0 2.1 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.4 AFZ81361.1 - 0.026 13.9 0.0 0.05 13.1 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 AFZ81361.1 - 0.026 14.4 0.0 0.1 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 AFZ81361.1 - 0.028 13.8 0.0 3.4 7.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 AFZ81361.1 - 0.12 12.6 0.0 0.18 12.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 AFZ81361.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase FeoB_N PF02421.13 AFZ81361.1 - 0.13 11.5 0.1 0.42 9.8 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B CAS_CSE1 PF03378.10 AFZ81362.1 - 5.6e-46 156.7 7.1 1.6e-45 155.2 4.9 1.7 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 AFZ81362.1 - 1.6e-45 155.3 11.5 2.6e-45 154.5 8.0 1.3 1 0 0 1 1 1 1 Cse1 RRM_1 PF00076.17 AFZ81363.1 - 4.3e-46 154.3 0.0 1.1e-22 79.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ81363.1 - 7.2e-34 115.6 0.0 1.8e-14 53.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ81363.1 - 1.1e-31 108.3 0.2 1.4e-11 44.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AFZ81363.1 - 0.0011 18.6 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 AFZ81363.1 - 0.0015 18.3 0.4 3.6 7.4 0.0 3.1 4 0 0 4 4 4 2 RNA binding motif SseB_C PF14581.1 AFZ81363.1 - 0.02 14.7 0.0 0.064 13.1 0.0 1.8 2 0 0 2 2 2 0 SseB protein C-terminal domain DUF4651 PF15513.1 AFZ81363.1 - 0.06 12.8 0.1 6.2 6.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4651) zf-RING_5 PF14634.1 AFZ81364.1 - 5.3e-09 35.6 7.7 1.1e-08 34.6 5.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 AFZ81364.1 - 1.7e-07 30.9 6.9 2.3e-07 30.5 4.0 1.9 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 AFZ81364.1 - 1.9e-07 30.6 10.4 1.7e-06 27.6 7.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AFZ81364.1 - 6.1e-07 29.3 10.0 4.1e-06 26.7 6.4 2.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AFZ81364.1 - 7.5e-07 28.7 4.8 1.6e-06 27.6 2.7 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AFZ81364.1 - 0.00012 22.0 4.1 0.0003 20.8 2.4 1.9 1 1 1 2 2 2 1 RING-H2 zinc finger Rtf2 PF04641.7 AFZ81364.1 - 0.00031 20.0 1.5 0.00031 20.0 1.0 1.6 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 AFZ81364.1 - 0.011 15.6 8.7 0.029 14.2 3.6 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4121 PF13497.1 AFZ81364.1 - 0.016 14.2 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) zf-RING_UBOX PF13445.1 AFZ81364.1 - 0.028 14.1 8.6 0.35 10.6 5.9 2.8 1 1 0 1 1 1 0 RING-type zinc-finger zinc-ribbons_6 PF07191.7 AFZ81364.1 - 0.1 12.3 4.3 0.37 10.6 2.1 2.1 2 0 0 2 2 2 0 zinc-ribbons zf-RING_4 PF14570.1 AFZ81364.1 - 0.19 11.3 9.2 1.5 8.4 6.7 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain SURF1 PF02104.10 AFZ81365.1 - 6e-33 114.4 0.1 3.2e-32 112.0 0.1 1.9 1 1 0 1 1 1 1 SURF1 family RabGAP-TBC PF00566.13 AFZ81366.1 - 4.1e-06 26.4 0.8 1e-05 25.1 0.2 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain zf-C2H2_2 PF12756.2 AFZ81368.1 - 0.00058 19.9 1.5 0.00069 19.6 1.0 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) CCDC84 PF14968.1 AFZ81368.1 - 0.00063 19.3 0.4 0.00074 19.1 0.3 1.1 1 0 0 1 1 1 1 Coiled coil protein 84 zf-C2H2_jaz PF12171.3 AFZ81368.1 - 0.066 13.3 4.3 0.14 12.3 3.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 AFZ81368.1 - 0.26 10.9 2.2 0.49 9.9 1.5 1.5 1 0 0 1 1 1 0 U1 zinc finger KID PF02524.9 AFZ81368.1 - 2.6 8.5 8.9 3.5 8.1 1.2 3.8 4 0 0 4 4 4 0 KID repeat tRNA_m1G_MT PF01746.16 AFZ81369.1 - 2.8e-24 85.7 0.2 3.7e-24 85.3 0.1 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase EF-hand_7 PF13499.1 AFZ81370.1 - 1.7e-05 24.8 0.1 0.0051 16.9 0.0 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 AFZ81370.1 - 0.0013 18.5 0.1 0.02 14.7 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain EF-hand_6 PF13405.1 AFZ81370.1 - 0.0013 18.4 0.2 0.97 9.4 0.0 4.0 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 AFZ81370.1 - 0.0072 15.5 0.1 1.5 8.3 0.0 3.9 4 0 0 4 4 4 1 EF hand DUF4476 PF14771.1 AFZ81370.1 - 0.034 14.1 0.6 1.6 8.8 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4476) zf-Tim10_DDP PF02953.10 AFZ81371.1 - 1.2e-10 40.4 2.4 1.5e-10 40.2 1.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CDtoxinA PF03498.9 AFZ81371.1 - 0.032 13.5 0.7 0.036 13.4 0.5 1.1 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family XPG_I PF00867.13 AFZ81372.1 - 9.1e-26 89.7 0.0 2.7e-25 88.2 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 AFZ81372.1 - 5e-18 65.2 0.0 1.1e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 AFZ81372.1 - 1.8e-05 24.3 0.0 4.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 AFZ81372.1 - 0.09 13.0 0.3 1.7 8.8 0.0 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Kelch_3 PF13415.1 AFZ81373.1 - 1e-25 89.2 0.2 1.9e-07 31.0 0.0 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 AFZ81373.1 - 8.7e-22 76.6 2.4 4.7e-07 29.4 0.1 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 AFZ81373.1 - 6.9e-17 61.0 4.3 6.7e-08 32.3 0.1 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 AFZ81373.1 - 2.4e-10 40.1 6.5 0.00031 20.7 0.3 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 AFZ81373.1 - 5e-08 32.4 4.8 0.00015 21.3 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 AFZ81373.1 - 1.6e-07 30.7 3.9 0.00082 18.8 0.2 3.5 4 0 0 4 4 4 2 Kelch motif Ret_tiss PF10044.4 AFZ81375.1 - 0.12 12.8 0.0 0.33 11.5 0.0 1.7 2 0 0 2 2 2 0 Retinal tissue protein Mannosyl_trans PF05007.8 AFZ81376.1 - 1.9e-64 217.8 30.2 1.9e-64 217.8 21.0 1.6 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 AFZ81376.1 - 5.5e-11 41.9 41.9 7.6e-11 41.4 29.1 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 AFZ81376.1 - 0.0017 17.9 0.1 0.0017 17.9 0.1 2.6 1 1 0 2 2 2 1 Protein of unknown function (DUF2029) RHD3 PF05879.7 AFZ81382.1 - 3.9e-93 312.7 11.6 2.2e-91 306.9 8.0 2.3 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 AFZ81382.1 - 1.9e-08 33.6 0.1 3.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 AFZ81382.1 - 0.0026 17.5 0.2 0.0064 16.3 0.2 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 AFZ81382.1 - 0.023 14.6 0.0 0.069 13.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rep_N PF08724.5 AFZ81382.1 - 0.033 13.7 0.1 0.35 10.3 0.0 2.5 2 0 0 2 2 2 0 Rep protein catalytic domain like Peptidase_C14 PF00656.17 AFZ81383.1 - 2e-36 125.9 0.0 4.5e-36 124.8 0.0 1.6 1 0 0 1 1 1 1 Caspase domain PEPcase_2 PF14010.1 AFZ81384.1 - 0.0037 15.6 1.6 0.0037 15.6 1.1 1.9 1 1 1 2 2 2 1 Phosphoenolpyruvate carboxylase FadA PF09403.5 AFZ81384.1 - 0.008 16.1 4.9 0.008 16.1 3.4 2.1 2 1 1 3 3 3 1 Adhesion protein FadA DUF1227 PF06777.6 AFZ81384.1 - 0.014 15.0 2.3 0.014 15.0 1.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1227) FliJ PF02050.11 AFZ81384.1 - 0.027 14.5 3.3 1.8 8.6 0.5 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein APG6 PF04111.7 AFZ81384.1 - 0.031 13.3 7.9 0.036 13.1 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Laminin_II PF06009.7 AFZ81384.1 - 0.072 12.8 2.9 0.17 11.6 2.0 1.6 1 0 0 1 1 1 0 Laminin Domain II Spectrin PF00435.16 AFZ81384.1 - 0.093 13.0 5.1 0.21 11.8 0.9 2.1 1 1 1 2 2 2 0 Spectrin repeat CTD_bind PF04818.8 AFZ81384.1 - 0.15 12.3 2.9 1.6 9.0 0.2 3.0 2 1 1 3 3 3 0 RNA polymerase II-binding domain. Tup_N PF08581.5 AFZ81384.1 - 0.21 11.7 9.1 0.39 10.9 0.6 2.4 2 0 0 2 2 2 0 Tup N-terminal ApoLp-III PF07464.6 AFZ81384.1 - 0.32 11.0 8.8 3.3 7.7 5.7 2.4 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DMPK_coil PF08826.5 AFZ81384.1 - 0.36 10.7 3.5 0.86 9.5 0.1 2.8 1 1 1 2 2 2 0 DMPK coiled coil domain like DUF1002 PF06207.6 AFZ81384.1 - 0.54 9.5 8.9 9.6 5.4 6.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1002) Syntaxin_2 PF14523.1 AFZ81384.1 - 0.85 9.6 7.0 0.17 11.9 0.9 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Wx5_PLAF3D7 PF09688.5 AFZ81384.1 - 1.7 8.6 9.5 0.4 10.6 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) Histone_HNS PF00816.16 AFZ81384.1 - 3.4 8.2 4.8 28 5.3 3.4 2.5 1 1 0 1 1 1 0 H-NS histone family IncA PF04156.9 AFZ81384.1 - 4.2 6.9 8.5 21 4.6 5.9 2.0 1 1 0 1 1 1 0 IncA protein TMPIT PF07851.8 AFZ81384.1 - 10 5.1 8.0 2.9 6.8 2.5 1.8 1 1 1 2 2 2 0 TMPIT-like protein Ribosomal_L44 PF00935.14 AFZ81386.1 - 6.3e-33 112.6 13.0 8.5e-33 112.2 9.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_S6 PF01250.12 AFZ81387.1 - 3.3e-10 39.6 0.0 4.4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 ABA_GPCR PF12430.3 AFZ81388.1 - 2.5e-13 49.6 6.8 2.5e-13 49.6 4.7 1.9 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF1218 PF06749.7 AFZ81388.1 - 0.025 15.0 0.1 0.025 15.0 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Arm PF00514.18 AFZ81389.1 - 0.0017 18.0 2.3 0.062 13.1 0.0 4.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat TPR_11 PF13414.1 AFZ81389.1 - 0.013 15.1 1.5 0.013 15.1 1.0 3.5 2 1 1 3 3 3 0 TPR repeat TPR_2 PF07719.12 AFZ81389.1 - 0.47 10.4 2.8 12 6.0 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 AFZ81389.1 - 4.9 6.9 8.0 9.6 6.0 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat OHA PF14418.1 AFZ81390.1 - 5.7e-19 67.3 0.0 1.5e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 OST-HTH Associated domain WD40 PF00400.27 AFZ81391.1 - 2.1e-40 135.1 33.4 2.5e-09 36.6 0.2 10.9 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.7 AFZ81391.1 - 5.9e-11 42.2 0.1 1.9e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Dip2/Utp12 Family eIF2A PF08662.6 AFZ81391.1 - 1.8e-05 24.5 1.0 0.36 10.4 0.0 5.3 4 1 2 6 6 6 1 Eukaryotic translation initiation factor eIF2A Utp13 PF08625.6 AFZ81391.1 - 0.012 15.2 0.2 0.029 14.0 0.1 1.6 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain TaqI_C PF12950.2 AFZ81391.1 - 0.079 12.7 1.1 0.44 10.3 0.1 2.3 2 0 0 2 2 2 0 TaqI-like C-terminal specificity domain Hom_end_hint PF05203.11 AFZ81394.1 - 0.0032 17.2 0.0 0.0062 16.2 0.0 1.4 1 1 0 1 1 1 1 Hom_end-associated Hint SprT-like PF10263.4 AFZ81395.1 - 1.3e-37 128.8 4.4 1.7e-37 128.5 3.0 1.2 1 0 0 1 1 1 1 SprT-like family EF1G PF00647.14 AFZ81396.1 - 1.2e-36 124.7 0.1 2.2e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 AFZ81396.1 - 0.00013 21.8 0.0 0.001 19.0 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AFZ81396.1 - 0.0078 16.6 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L6e PF01159.14 AFZ81397.1 - 2.5e-28 98.4 0.1 4.6e-28 97.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Peptidase_M41 PF01434.13 AFZ81398.1 - 1.2e-58 198.1 1.0 1.8e-58 197.5 0.7 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AFZ81398.1 - 6.7e-41 139.5 0.0 3.2e-40 137.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 AFZ81398.1 - 6.5e-05 21.8 0.8 0.0004 19.2 0.0 2.4 2 1 1 3 3 3 1 TIP49 C-terminus AAA_17 PF13207.1 AFZ81398.1 - 0.00024 21.9 0.0 0.001 19.8 0.0 2.2 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 AFZ81398.1 - 0.00024 20.2 0.1 0.00075 18.6 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 AFZ81398.1 - 0.00024 21.1 0.7 0.015 15.2 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 AFZ81398.1 - 0.0021 17.4 0.7 0.43 9.9 0.2 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 AFZ81398.1 - 0.0028 16.7 0.0 0.0073 15.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 AFZ81398.1 - 0.0063 16.4 0.1 0.017 15.0 0.1 1.8 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 AFZ81398.1 - 0.0066 16.1 0.1 0.016 14.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 AFZ81398.1 - 0.016 15.0 0.0 0.051 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 AFZ81398.1 - 0.017 14.8 0.3 0.1 12.3 0.1 2.5 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AFZ81398.1 - 0.02 14.7 0.0 0.087 12.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AFZ81398.1 - 0.025 14.6 0.2 0.59 10.2 0.1 2.7 1 1 0 2 2 2 0 AAA domain KaiC PF06745.8 AFZ81398.1 - 0.032 13.3 0.6 0.14 11.2 0.0 2.3 3 0 0 3 3 3 0 KaiC Mg_chelatase PF01078.16 AFZ81398.1 - 0.032 13.3 0.1 0.13 11.3 0.2 1.9 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 AFZ81398.1 - 0.033 13.6 0.8 0.12 11.7 0.2 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein PhaP_Bmeg PF09602.5 AFZ81398.1 - 0.042 13.6 0.1 0.074 12.8 0.1 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) AAA_18 PF13238.1 AFZ81398.1 - 0.043 14.1 0.4 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RRM_6 PF14259.1 AFZ81399.1 - 0.069 13.1 0.2 14 5.7 0.1 3.9 3 1 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Kri1_C PF12936.2 AFZ81400.1 - 2.7e-14 52.8 0.1 2.7e-14 52.8 0.1 3.3 3 1 0 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.7 AFZ81400.1 - 4.1e-07 30.1 3.4 4.1e-07 30.1 2.4 3.4 4 1 0 4 4 4 1 KRI1-like family ZZ PF00569.12 AFZ81400.1 - 0.17 11.4 9.4 0.36 10.3 6.5 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type zf-UBR PF02207.15 AFZ81400.1 - 0.92 9.2 9.0 1.8 8.3 6.2 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) AAA_23 PF13476.1 AFZ81403.1 - 5.2e-13 49.7 0.3 5.2e-13 49.7 0.2 5.8 2 2 3 5 5 5 1 AAA domain SMC_N PF02463.14 AFZ81403.1 - 4.6e-11 42.3 31.7 4.5e-10 39.1 22.0 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AFZ81403.1 - 0.0035 16.8 0.0 0.0074 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DEAD PF00270.24 AFZ81404.1 - 9.1e-19 67.5 0.0 2.2e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ81404.1 - 6.8e-17 61.1 0.0 1.9e-16 59.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RQC PF09382.5 AFZ81404.1 - 7.5e-10 38.4 0.0 2.1e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 RQC domain Thymidylat_synt PF00303.14 AFZ81407.1 - 2.5e-116 387.3 0.0 3.7e-116 386.8 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.14 AFZ81407.1 - 1.8e-27 95.8 0.0 1.3e-26 93.1 0.0 2.0 1 1 0 1 1 1 1 Dihydrofolate reductase Pkinase PF00069.20 AFZ81408.1 - 3.5e-27 95.2 0.1 8.4e-27 93.9 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ81408.1 - 1.1e-18 67.2 0.0 2.1e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1002 PF06207.6 AFZ81408.1 - 0.072 12.3 0.2 0.072 12.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) Myb_DNA-binding PF00249.26 AFZ81409.1 - 6.2e-06 26.1 0.2 0.046 13.7 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AFZ81409.1 - 0.011 15.7 3.6 0.52 10.4 0.2 3.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Hat1_N PF10394.4 AFZ81410.1 - 4e-27 95.2 12.2 1.3e-26 93.5 7.3 2.5 2 1 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.13 AFZ81410.1 - 0.0026 17.0 0.5 0.0093 15.2 0.0 2.2 2 0 0 2 2 2 1 MOZ/SAS family Acetyltransf_7 PF13508.1 AFZ81410.1 - 0.08 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AFZ81410.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MCM PF00493.18 AFZ81411.1 - 9e-74 248.2 0.1 2.3e-71 240.3 0.1 2.9 2 1 0 2 2 2 2 MCM2/3/5 family Mg_chelatase PF01078.16 AFZ81411.1 - 2.6e-08 33.2 0.2 1.1e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AFZ81411.1 - 0.0012 18.3 0.1 0.74 9.2 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.24 AFZ81411.1 - 0.0073 16.5 0.0 0.023 14.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AFZ81411.1 - 0.008 15.9 0.0 0.066 12.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AFZ81411.1 - 0.047 13.8 0.1 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 AFZ81411.1 - 0.16 11.9 0.3 0.32 10.9 0.2 1.4 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_L37 PF08561.5 AFZ81413.1 - 1.3e-13 50.3 0.2 2.1e-13 49.6 0.1 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 GTP_EFTU PF00009.22 AFZ81414.1 - 2.1e-46 157.7 0.0 2.5e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AFZ81414.1 - 3.4e-16 59.2 0.0 9.2e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AFZ81414.1 - 2.5e-05 24.3 0.0 0.0001 22.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AFZ81414.1 - 0.00095 19.1 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.10 AFZ81414.1 - 0.0012 18.1 2.5 0.0012 18.1 1.8 2.2 2 0 0 2 2 2 1 Ataxin-2 C-terminal region LRR_8 PF13855.1 AFZ81415.1 - 3e-07 30.0 6.4 0.00015 21.4 1.1 5.3 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 AFZ81415.1 - 6.2e-07 28.8 25.9 0.008 15.7 0.0 6.8 2 1 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 AFZ81415.1 - 2.6e-05 23.7 11.8 16 6.2 0.0 8.5 9 1 0 9 9 9 1 Leucine rich repeat LRR_6 PF13516.1 AFZ81415.1 - 3.6e-05 23.3 23.2 0.88 9.8 0.5 9.2 9 1 1 10 10 10 2 Leucine Rich repeat LRR_1 PF00560.28 AFZ81415.1 - 0.00012 21.6 21.7 2 8.7 0.6 8.4 6 3 1 7 7 7 3 Leucine Rich Repeat ATHILA PF03078.10 AFZ81415.1 - 0.062 11.8 0.0 0.091 11.3 0.0 1.2 1 0 0 1 1 1 0 ATHILA ORF-1 family Pkinase PF00069.20 AFZ81416.1 - 3.6e-71 239.3 0.7 3.6e-71 239.3 0.5 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ81416.1 - 3.1e-39 134.6 0.8 4.7e-39 134.0 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PH PF00169.24 AFZ81416.1 - 1.1e-11 44.8 0.1 3.9e-11 43.0 0.1 2.1 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.27 AFZ81416.1 - 2.5e-11 42.0 6.2 0.0019 17.3 0.3 4.0 3 0 0 3 3 3 3 EF hand Kinase-like PF14531.1 AFZ81416.1 - 9.3e-10 37.9 0.1 1.8e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like EF-hand_6 PF13405.1 AFZ81416.1 - 1.7e-09 36.7 4.7 0.011 15.5 0.0 4.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 AFZ81416.1 - 1.4e-08 34.7 8.2 7.8e-07 29.1 0.9 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.1 AFZ81416.1 - 1.1e-07 31.4 3.2 0.022 14.3 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 AFZ81416.1 - 8.1e-07 28.1 1.4 0.018 14.3 0.5 3.8 3 0 0 3 3 3 2 EF hand Kdo PF06293.9 AFZ81416.1 - 4.6e-05 22.5 0.4 9.2e-05 21.6 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.1 AFZ81416.1 - 0.014 15.6 0.5 0.1 12.8 0.1 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain APH PF01636.18 AFZ81416.1 - 0.39 10.3 0.0 2.4 7.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-UBR PF02207.15 AFZ81417.1 - 4.6e-15 55.0 14.8 4.6e-15 55.0 10.3 3.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) DUF2726 PF10881.3 AFZ81417.1 - 0.034 13.7 0.1 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) PRP21_like_P PF12230.3 AFZ81418.1 - 9.4e-41 139.8 8.1 4.8e-40 137.4 5.6 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 AFZ81418.1 - 5.4e-34 115.6 0.9 2.4e-16 59.0 0.0 2.4 2 0 0 2 2 2 2 Surp module DUF1682 PF07946.9 AFZ81418.1 - 0.0062 15.4 0.0 0.0062 15.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) RrnaAD PF00398.15 AFZ81420.1 - 8.8e-56 188.8 0.0 1.2e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 AFZ81420.1 - 6.7e-11 41.9 0.0 1.7e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AFZ81420.1 - 4.2e-08 33.2 0.0 7.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AFZ81420.1 - 1.7e-06 27.2 0.0 4.9e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.7 AFZ81420.1 - 3.2e-06 27.5 0.0 9.3e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AFZ81420.1 - 5.5e-06 25.6 0.0 8.8e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 AFZ81420.1 - 5.9e-06 26.8 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AFZ81420.1 - 2.9e-05 23.8 0.0 5.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AFZ81420.1 - 0.00019 21.8 0.0 0.00038 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AFZ81420.1 - 0.0002 20.9 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 AFZ81420.1 - 0.00096 18.5 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 AFZ81420.1 - 0.002 18.4 0.0 0.0042 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 AFZ81420.1 - 0.0085 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase DUF43 PF01861.11 AFZ81420.1 - 0.019 13.9 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF43 NodS PF05401.6 AFZ81420.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 AFZ81420.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 AFZ81420.1 - 0.088 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HEAT PF02985.17 AFZ81421.1 - 6.2e-21 72.5 18.1 0.0054 16.7 0.1 11.7 13 0 0 13 13 13 5 HEAT repeat HEAT_2 PF13646.1 AFZ81421.1 - 1.1e-19 70.4 0.5 0.0027 17.9 0.0 7.0 5 2 2 7 7 7 5 HEAT repeats Vac14_Fab1_bd PF12755.2 AFZ81421.1 - 6.4e-07 29.6 6.4 7.4e-06 26.2 0.5 4.5 3 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 AFZ81421.1 - 9.5e-06 25.9 1.6 8.3 7.0 0.0 6.5 7 0 0 7 7 7 1 HEAT-like repeat Adaptin_N PF01602.15 AFZ81421.1 - 5.6e-05 21.6 15.2 0.038 12.3 0.3 3.1 2 1 0 2 2 2 2 Adaptin N terminal region CLASP_N PF12348.3 AFZ81421.1 - 0.011 15.1 2.5 1.4 8.2 0.0 3.3 2 2 1 3 3 3 0 CLASP N terminal DUF4042 PF13251.1 AFZ81421.1 - 0.011 15.1 0.9 18 4.7 0.1 4.9 6 1 0 6 6 6 0 Domain of unknown function (DUF4042) DUF1546 PF07571.8 AFZ81421.1 - 0.012 15.7 0.0 0.26 11.4 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1546) Arm PF00514.18 AFZ81421.1 - 0.016 15.0 0.0 0.25 11.2 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat ALAD PF00490.16 AFZ81422.1 - 7.3e-90 301.1 0.2 1.4e-89 300.2 0.1 1.5 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Peptidase_M16_C PF05193.16 AFZ81422.1 - 1.2e-24 87.0 0.1 5.4e-12 45.7 0.0 3.1 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AFZ81422.1 - 9.3e-16 57.9 1.3 6.2e-15 55.2 0.2 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) zf-B_box PF00643.19 AFZ81423.1 - 1.9e-10 40.4 18.8 4.3e-06 26.5 3.5 2.5 2 0 0 2 2 2 2 B-box zinc finger RNA_pol_L_2 PF13656.1 AFZ81424.1 - 1.7e-29 101.0 0.0 1.9e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 AFZ81424.1 - 9.5e-08 31.0 0.0 2.3e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain tRNA-synt_2 PF00152.15 AFZ81425.1 - 2.5e-75 253.3 0.0 3.3e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 AFZ81425.1 - 6.2e-09 35.4 0.0 1.5e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 AFZ81425.1 - 2.2e-05 24.1 0.2 7.9e-05 22.4 0.2 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 AFZ81425.1 - 0.039 13.5 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) FAINT PF04385.10 AFZ81426.1 - 1.1e-06 28.3 0.7 5e-06 26.2 0.2 2.0 1 1 1 2 2 2 1 Domain of unknown function, DUF529 Prefoldin_2 PF01920.15 AFZ81427.1 - 9.7e-17 60.6 0.7 1.2e-16 60.4 0.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit Nsp1_C PF05064.8 AFZ81427.1 - 0.022 14.3 0.6 0.041 13.5 0.1 1.6 2 0 0 2 2 2 0 Nsp1-like C-terminal region Prefoldin PF02996.12 AFZ81427.1 - 0.027 14.1 3.3 0.2 11.3 0.1 2.0 1 1 0 2 2 2 0 Prefoldin subunit WXG100 PF06013.7 AFZ81427.1 - 0.13 12.2 0.1 1 9.4 0.0 2.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG XhlA PF10779.4 AFZ81427.1 - 0.69 9.8 2.4 2.3 8.2 0.1 2.1 2 0 0 2 2 2 0 Haemolysin XhlA RRM_1 PF00076.17 AFZ81431.1 - 8.8e-07 28.4 0.1 3.5e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ81431.1 - 7e-05 22.6 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CHASE PF03924.8 AFZ81431.1 - 0.0013 18.0 1.9 0.11 11.6 0.1 2.3 2 0 0 2 2 2 2 CHASE domain RRM_6 PF14259.1 AFZ81431.1 - 0.011 15.7 0.0 0.045 13.7 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FAINT PF04385.10 AFZ81432.1 - 1.4e-09 37.6 8.2 0.048 13.5 0.0 5.8 5 0 0 5 5 5 5 Domain of unknown function, DUF529 TIM PF00121.13 AFZ81433.1 - 3.8e-60 202.9 0.1 4.6e-60 202.7 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase BRX_N PF13713.1 AFZ81433.1 - 0.087 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Prefoldin_3 PF13758.1 AFZ81433.1 - 0.12 12.1 0.1 0.62 9.8 0.0 2.1 2 1 0 2 2 2 0 Prefoldin subunit MobB PF03205.9 AFZ81434.1 - 3.2e-05 23.6 0.0 5.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 AFZ81434.1 - 0.00033 20.3 0.0 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 AFZ81434.1 - 0.019 14.9 0.0 0.065 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Carb_bind PF10645.4 AFZ81434.1 - 0.044 13.5 1.1 0.15 11.8 0.1 2.2 2 0 0 2 2 2 0 Carbohydrate binding RNA_helicase PF00910.17 AFZ81434.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 AFZ81434.1 - 0.073 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain MipZ PF09140.6 AFZ81434.1 - 0.078 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase MipZ ABC_tran PF00005.22 AFZ81434.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 AFZ81434.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AFZ81434.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 AFZ81434.1 - 0.18 11.3 0.0 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad21_Rec8_N PF04825.8 AFZ81436.1 - 3.5e-08 33.3 0.7 1.1e-07 31.7 0.1 2.0 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 AFZ81436.1 - 0.0017 17.5 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Motile_Sperm PF00635.21 AFZ81437.1 - 1e-24 86.2 0.1 1.6e-24 85.6 0.1 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain RNA_pol_Rpb6 PF01192.17 AFZ81438.1 - 3.7e-17 61.7 0.1 6e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb6 FAINT PF04385.10 AFZ81440.1 - 0.0039 16.9 0.1 0.0099 15.7 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function, DUF529 T4-Gluco-transf PF09198.5 AFZ81440.1 - 0.12 11.6 0.1 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage T4 beta-glucosyltransferase LNS2 PF08235.8 AFZ81441.1 - 2.7e-63 212.2 0.0 4.2e-63 211.6 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 AFZ81441.1 - 2.2e-25 88.4 0.1 8.4e-25 86.5 0.0 1.9 1 1 0 1 1 1 1 lipin, N-terminal conserved region zf-DHHC PF01529.15 AFZ81442.1 - 7e-27 93.9 11.1 7e-27 93.9 7.7 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.2 AFZ81442.1 - 5.9e-26 90.6 0.3 6.9e-14 51.9 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AFZ81442.1 - 4.1e-23 81.3 1.0 1e-08 35.4 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 AFZ81442.1 - 9e-22 75.7 4.8 1.6e-08 33.9 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 AFZ81442.1 - 7.3e-19 65.9 4.3 0.00034 20.5 0.1 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 AFZ81442.1 - 6.1e-18 64.4 1.3 8.5e-08 32.2 0.1 4.9 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Spc97_Spc98 PF04130.8 AFZ81443.1 - 1.3e-48 165.7 21.5 8.4e-33 113.4 5.9 2.9 2 1 0 2 2 2 2 Spc97 / Spc98 family 2-oxoacid_dh PF00198.18 AFZ81444.1 - 1.6e-67 227.1 0.1 2.2e-67 226.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 AFZ81444.1 - 1.9e-18 65.8 1.4 3.9e-18 64.8 1.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 AFZ81444.1 - 5.7e-11 41.8 0.3 1.6e-10 40.3 0.2 1.8 1 0 0 1 1 1 1 e3 binding domain HlyD PF00529.15 AFZ81444.1 - 0.0022 17.3 0.1 0.0042 16.4 0.1 1.5 1 0 0 1 1 1 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 AFZ81444.1 - 0.0036 16.9 0.3 0.011 15.3 0.2 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like GCV_H PF01597.14 AFZ81444.1 - 0.021 14.4 0.1 0.048 13.3 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_3 PF13437.1 AFZ81444.1 - 0.035 14.4 0.1 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 HlyD family secretion protein SASP PF00269.15 AFZ81444.1 - 0.055 13.3 1.0 1 9.2 0.1 2.8 2 1 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type PYNP_C PF07831.8 AFZ81444.1 - 0.1 12.0 0.5 4.1 6.9 0.0 2.6 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain IMCp PF12314.3 AFZ81445.1 - 9.2e-32 109.0 95.0 3.4e-20 72.0 26.9 4.0 1 1 3 4 4 4 4 Inner membrane complex protein Claudin_2 PF13903.1 AFZ81446.1 - 0.0074 15.9 6.9 0.027 14.1 4.7 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction TLD PF07534.11 AFZ81447.1 - 4.9e-17 62.2 0.0 1.2e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.13 AFZ81447.1 - 5.1e-14 52.2 3.4 1.9e-13 50.4 2.0 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Rad51 PF08423.6 AFZ81448.1 - 1.9e-10 40.0 0.0 2.3e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 AFZ81448.1 - 0.00016 21.0 0.1 0.00022 20.6 0.1 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 AFZ81449.1 - 1.1e-10 41.1 0.0 1.4e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.6 AFZ81449.1 - 4.2e-10 38.9 0.0 4.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 KaiC PF06745.8 AFZ81449.1 - 5.8e-08 32.1 0.1 7.1e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 AFZ81449.1 - 5.1e-06 26.0 0.0 5.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain PAXNEB PF05625.6 AFZ81449.1 - 0.0016 17.3 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 PAXNEB protein UPF0079 PF02367.12 AFZ81449.1 - 0.0029 17.2 0.0 0.0036 16.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 AFZ81449.1 - 0.0048 17.0 0.1 0.041 14.0 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 AFZ81449.1 - 0.012 15.7 0.0 0.038 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.10 AFZ81449.1 - 0.017 14.0 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ABC_tran PF00005.22 AFZ81449.1 - 0.021 15.1 0.1 0.028 14.7 0.1 1.2 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 AFZ81449.1 - 0.021 14.5 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 AFZ81449.1 - 0.025 14.2 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 AFZ81449.1 - 0.031 13.8 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AFZ81449.1 - 0.031 14.2 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 AFZ81449.1 - 0.043 13.4 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 NACHT domain TcdB_toxin_midN PF12256.3 AFZ81449.1 - 0.048 13.0 0.0 0.067 12.6 0.0 1.1 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region AAA_33 PF13671.1 AFZ81449.1 - 0.07 13.0 0.0 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 AFZ81449.1 - 0.07 13.3 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 AFZ81449.1 - 0.11 11.2 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_10 PF12846.2 AFZ81449.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain DIX PF00778.12 AFZ81451.1 - 8.8e-05 22.1 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 DIX domain DUF966 PF06136.8 AFZ81451.1 - 0.043 13.2 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF3311 PF11755.3 AFZ81452.1 - 6.4 6.4 12.3 4.3 6.9 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) Fumble PF03630.9 AFZ81453.1 - 4e-37 127.8 1.5 7.4e-36 123.6 1.0 2.7 1 1 0 1 1 1 1 Fumble DUF3336 PF11815.3 AFZ81453.1 - 0.0083 15.6 0.2 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Exo_endo_phos_2 PF14529.1 AFZ81455.1 - 0.036 13.6 0.1 0.086 12.4 0.1 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase NADH_dh_m_C1 PF15088.1 AFZ81455.1 - 0.18 11.3 1.0 0.42 10.1 0.1 2.0 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial zf-CCCH PF00642.19 AFZ81456.1 - 5.5e-09 35.4 18.3 8.4e-07 28.5 1.7 4.2 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Hormone_5 PF00184.12 AFZ81456.1 - 1.5 9.3 6.1 3.1 8.4 4.2 1.5 1 0 0 1 1 1 0 Neurohypophysial hormones, C-terminal Domain zf-C2H2_jaz PF12171.3 AFZ81457.1 - 1.7e-05 24.7 4.3 1.7e-05 24.7 3.0 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 AFZ81457.1 - 9.5e-05 21.8 0.7 0.00022 20.7 0.5 1.6 1 0 0 1 1 1 1 U1 zinc finger Wbp11 PF09429.5 AFZ81457.1 - 0.013 15.4 1.5 0.013 15.4 1.1 1.6 2 0 0 2 2 2 0 WW domain binding protein 11 zf-met PF12874.2 AFZ81457.1 - 0.024 14.8 1.6 0.024 14.8 1.1 2.2 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AFZ81457.1 - 0.034 14.2 0.6 0.034 14.2 0.4 1.6 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 AFZ81457.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 AFZ81457.1 - 0.19 11.9 1.9 0.51 10.6 1.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 AFZ81457.1 - 0.21 11.9 0.3 0.21 11.9 0.2 2.7 3 0 0 3 3 3 0 Zinc-finger double domain Pkinase PF00069.20 AFZ81458.1 - 7.1e-37 126.9 0.7 2.3e-36 125.3 0.2 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ81458.1 - 6.7e-19 67.9 0.1 1.3e-18 67.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Cyclin_N PF00134.18 AFZ81458.1 - 2.2e-08 33.7 0.4 5.5e-08 32.4 0.3 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain F-box-like PF12937.2 AFZ81458.1 - 0.019 14.6 0.0 0.062 13.0 0.0 1.9 1 0 0 1 1 1 0 F-box-like JAB PF01398.16 AFZ81459.1 - 4.6e-15 55.3 0.4 7.3e-15 54.7 0.3 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 AFZ81459.1 - 0.00018 21.5 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function BRCT PF00533.21 AFZ81460.1 - 0.025 14.7 0.0 0.42 10.7 0.0 2.9 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain PIGA PF08288.7 AFZ81461.1 - 0.083 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 PIGA (GPI anchor biosynthesis) ATP-synt_ab PF00006.20 AFZ81462.1 - 2e-58 197.4 0.0 2.6e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AFZ81462.1 - 6.9e-17 61.9 0.1 1.2e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AFZ81462.1 - 4.3e-11 42.8 1.7 7.3e-11 42.1 1.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 AFZ81462.1 - 0.00019 21.2 0.5 0.00037 20.3 0.4 1.5 1 0 0 1 1 1 1 HAS barrel domain DUF3584 PF12128.3 AFZ81464.1 - 0.00018 19.0 14.8 0.00018 19.0 10.2 3.7 3 1 1 4 4 4 3 Protein of unknown function (DUF3584) DUF2353 PF09789.4 AFZ81464.1 - 0.0028 16.9 18.6 0.0028 16.9 12.9 3.6 2 1 2 4 4 4 1 Uncharacterized coiled-coil protein (DUF2353) Reo_sigmaC PF04582.7 AFZ81464.1 - 4.5 6.3 24.4 0.53 9.4 3.8 4.1 2 1 1 4 4 4 0 Reovirus sigma C capsid protein Mto2_bdg PF12808.2 AFZ81464.1 - 6.9 6.8 15.8 0.12 12.5 0.8 5.0 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Rpn3_C PF08375.6 AFZ81465.1 - 4.9e-19 68.4 0.0 1.1e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 AFZ81465.1 - 2.9e-18 66.0 0.0 1e-17 64.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 AFZ81465.1 - 0.054 13.4 10.0 0.23 11.4 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.1 AFZ81465.1 - 0.088 12.7 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 PPR repeat family TPR_12 PF13424.1 AFZ81465.1 - 0.1 12.5 8.4 0.35 10.8 2.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ste50p-SAM PF09235.5 AFZ81465.1 - 0.11 12.4 0.0 0.45 10.5 0.0 2.0 1 0 0 1 1 1 0 Ste50p, sterile alpha motif TPR_11 PF13414.1 AFZ81465.1 - 0.81 9.3 8.7 9.2 6.0 0.2 3.2 2 1 1 3 3 3 0 TPR repeat TMF_DNA_bd PF12329.3 AFZ81466.1 - 0.75 9.6 14.6 0.17 11.6 3.2 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding FAINT PF04385.10 AFZ81467.1 - 3.2e-08 33.2 6.1 0.0031 17.3 0.1 4.0 4 0 0 4 4 4 3 Domain of unknown function, DUF529 EMA PF02488.10 AFZ81467.1 - 7.4e-07 28.8 0.1 0.0065 15.9 0.0 2.2 1 1 1 2 2 2 2 Merozoite Antigen vATP-synt_AC39 PF01992.11 AFZ81468.1 - 8.7e-56 189.4 0.3 1.2e-54 185.7 0.2 1.9 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit YL1 PF05764.8 AFZ81470.1 - 3.8e-45 154.3 19.7 3.8e-45 154.3 13.6 1.8 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 AFZ81470.1 - 4.8e-10 38.8 1.2 9.4e-10 37.8 0.3 1.9 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain PRP38 PF03371.10 AFZ81471.1 - 0.0058 16.2 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 PRP38 family DivIC PF04977.10 AFZ81472.1 - 7.3e-06 25.3 10.3 0.0015 17.9 2.6 3.6 3 0 0 3 3 3 2 Septum formation initiator Cep57_MT_bd PF06657.8 AFZ81472.1 - 0.00037 20.3 0.0 0.00037 20.3 0.0 3.0 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 WD40_alt PF14077.1 AFZ81472.1 - 0.00043 19.8 0.2 0.016 14.8 0.0 2.6 2 0 0 2 2 2 1 Alternative WD40 repeat motif bZIP_1 PF00170.16 AFZ81472.1 - 0.0053 16.6 21.3 0.012 15.5 0.3 4.6 3 2 2 5 5 5 2 bZIP transcription factor Cep57_CLD_2 PF14197.1 AFZ81472.1 - 0.0087 15.9 20.4 0.14 12.1 0.1 4.7 3 1 2 5 5 5 2 Centrosome localisation domain of PPC89 Reo_sigmaC PF04582.7 AFZ81472.1 - 0.023 13.9 3.9 0.48 9.5 0.3 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 AFZ81472.1 - 0.025 14.3 15.0 1 9.1 0.1 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Prefoldin PF02996.12 AFZ81472.1 - 0.055 13.1 11.7 3.5 7.2 0.0 4.7 4 1 0 4 4 4 0 Prefoldin subunit DUF972 PF06156.8 AFZ81472.1 - 0.095 13.0 18.6 1.4 9.3 0.1 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF972) CENP-Q PF13094.1 AFZ81472.1 - 0.22 11.5 16.7 1.2 9.0 0.1 3.2 4 0 0 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit Shugoshin_N PF07558.6 AFZ81472.1 - 0.51 10.0 11.2 0.32 10.7 0.4 3.6 3 1 1 4 4 4 0 Shugoshin N-terminal coiled-coil region IncA PF04156.9 AFZ81472.1 - 0.53 9.8 17.9 7.8 6.0 0.1 2.9 2 1 0 2 2 2 0 IncA protein DUF2205 PF10224.4 AFZ81472.1 - 0.93 9.1 13.2 2.6 7.6 0.1 3.1 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) ADIP PF11559.3 AFZ81472.1 - 1.3 8.9 24.5 0.13 12.1 8.8 3.3 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.10 AFZ81472.1 - 1.4 8.8 19.5 2 8.2 0.1 4.7 3 1 1 4 4 4 0 Basic region leucine zipper Tropomyosin_1 PF12718.2 AFZ81472.1 - 3.2 7.6 17.7 0.48 10.2 3.6 3.4 3 0 0 3 3 3 0 Tropomyosin like HALZ PF02183.13 AFZ81472.1 - 9.9 5.9 14.7 2.4 7.9 0.4 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper CBF PF03914.12 AFZ81473.1 - 6.9e-07 28.8 3.4 4.8e-05 22.8 0.9 2.8 2 1 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 AFZ81473.1 - 0.00014 22.0 0.0 0.00046 20.4 0.0 1.9 1 0 0 1 1 1 1 Nucleolar complex-associated protein UPF0113 PF03657.8 AFZ81474.1 - 2.3e-13 50.1 0.0 2.7e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 AFZ81474.1 - 5.6e-05 23.1 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 pre-rRNA processing and ribosome biogenesis SICA_C PF12879.2 AFZ81474.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain DUF1351 PF07083.6 AFZ81475.1 - 0.018 14.6 0.1 0.024 14.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) DUF4588 PF15251.1 AFZ81475.1 - 0.067 13.1 3.1 0.085 12.8 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AP2 PF00847.15 AFZ81476.1 - 2.9e-12 46.5 0.1 6.2e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 AP2 domain FAINT PF04385.10 AFZ81479.1 - 2.5e-18 65.6 2.1 7.2e-09 35.3 0.1 3.5 3 0 0 3 3 3 3 Domain of unknown function, DUF529 DUF4596 PF15363.1 AFZ81479.1 - 4.8e-05 23.1 11.3 50 3.9 0.0 8.0 7 0 0 7 7 7 5 Domain of unknown function (DUF4596) PC_rep PF01851.17 AFZ81480.1 - 3e-31 105.8 7.5 6.8e-07 29.1 0.1 7.9 7 0 0 7 7 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 AFZ81480.1 - 7e-11 42.2 0.8 2.6e-05 24.4 0.1 5.3 3 1 4 7 7 7 3 HEAT repeats HEAT PF02985.17 AFZ81480.1 - 0.00023 20.9 0.9 0.88 9.8 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 AFZ81480.1 - 0.0029 18.0 0.9 1.9 9.1 0.0 3.8 3 1 0 3 3 3 2 HEAT-like repeat Metallophos PF00149.23 AFZ81481.1 - 9.5e-38 129.5 0.5 2.5e-37 128.2 0.2 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Kelch_3 PF13415.1 AFZ81481.1 - 8.9e-29 98.9 11.6 1.4e-05 25.1 0.0 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 AFZ81481.1 - 6.6e-26 89.7 2.3 1.5e-05 24.8 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 AFZ81481.1 - 1.6e-25 88.5 9.8 5.1e-05 22.9 0.0 7.0 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 AFZ81481.1 - 5.1e-18 64.0 2.0 0.00065 19.3 0.0 6.4 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.20 AFZ81481.1 - 1.3e-16 59.8 0.8 6.2e-05 22.4 0.0 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 AFZ81481.1 - 7.2e-16 57.6 8.0 0.003 17.6 0.0 6.7 4 2 2 6 6 6 4 Kelch motif Ribosomal_S3_C PF00189.15 AFZ81482.1 - 1.8e-17 63.3 1.1 3.4e-17 62.4 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 AFZ81482.1 - 8e-10 38.1 0.1 1.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 AFZ81482.1 - 0.013 15.7 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 MARVEL PF01284.18 AFZ81483.1 - 0.083 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Membrane-associating domain BK_channel_a PF03493.13 AFZ81484.1 - 1.1e-20 73.4 3.5 1e-19 70.3 0.3 3.0 3 0 0 3 3 3 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 AFZ81484.1 - 3.4e-08 33.0 9.1 3.4e-08 33.0 6.3 3.6 3 1 1 4 4 4 1 Ion channel CRPA PF05745.6 AFZ81485.1 - 0.013 15.2 0.5 0.016 15.0 0.3 1.2 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Pox_P21 PF05313.7 AFZ81485.1 - 0.015 14.5 1.5 0.019 14.2 1.0 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein ATG22 PF11700.3 AFZ81485.1 - 0.029 12.8 0.2 0.03 12.8 0.2 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF4282 PF14110.1 AFZ81485.1 - 0.065 13.4 2.9 0.083 13.0 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF3792 PF12670.2 AFZ81485.1 - 0.075 12.8 2.0 0.087 12.6 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) DUF3675 PF12428.3 AFZ81485.1 - 0.14 12.4 1.0 0.19 11.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DUF4342 PF14242.1 AFZ81485.1 - 1.6 8.5 4.7 2 8.2 1.0 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4342) Lactamase_B_2 PF12706.2 AFZ81486.1 - 6.8e-33 113.8 1.4 9.6e-33 113.3 1.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AFZ81486.1 - 3.1e-09 36.7 0.5 2.6e-08 33.7 0.3 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 AFZ81487.1 - 2.1e-06 27.1 0.0 2.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 tRNase Z endonuclease Med4 PF10018.4 AFZ81488.1 - 0.023 14.1 0.1 0.042 13.2 0.1 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CHB_HEX_C PF03174.8 AFZ81488.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF676 PF05057.9 AFZ81489.1 - 5.6e-26 91.1 0.2 9.9e-26 90.3 0.1 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 AFZ81489.1 - 1.3e-06 28.2 0.8 6.8e-06 25.8 0.6 2.0 1 1 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 AFZ81489.1 - 0.00024 20.2 1.1 0.0033 16.4 0.0 2.2 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 AFZ81489.1 - 0.023 14.0 0.3 0.68 9.2 0.0 2.5 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.2 AFZ81489.1 - 0.062 13.1 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family FAINT PF04385.10 AFZ81492.1 - 5.4e-08 32.5 0.1 2e-06 27.5 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function, DUF529 Spectrin PF00435.16 AFZ81493.1 - 0.041 14.1 3.3 7 6.9 0.1 3.1 2 0 0 2 2 2 0 Spectrin repeat Phage_connect_1 PF05135.8 AFZ81493.1 - 0.43 10.7 6.8 9.3 6.4 0.1 4.1 3 1 1 4 4 4 0 Phage gp6-like head-tail connector protein NPV_P10 PF05531.7 AFZ81493.1 - 7.8 6.8 12.0 3 8.1 0.4 5.5 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein FadR_C PF07840.7 AFZ81494.1 - 0.088 12.4 0.1 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 FadR C-terminal domain Trp_oprn_chp PF09534.5 AFZ81495.1 - 0.11 12.0 0.2 0.11 12.0 0.1 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PFU PF09070.6 AFZ81496.1 - 0.0031 17.4 0.3 0.0043 17.0 0.2 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) Membrane_bind PF14564.1 AFZ81496.1 - 0.0086 16.2 0.6 0.015 15.4 0.4 1.4 1 0 0 1 1 1 1 Membrane binding Interfer-bind PF09294.5 AFZ81496.1 - 0.027 14.5 0.4 0.065 13.2 0.1 1.8 1 1 1 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III PapC_C PF13953.1 AFZ81496.1 - 0.051 13.2 0.1 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 PapC C-terminal domain fn3 PF00041.16 AFZ81496.1 - 0.058 13.5 0.2 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Fibronectin type III domain DUF2293 PF10056.4 AFZ81497.1 - 0.028 14.3 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) PP2C PF00481.16 AFZ81498.1 - 4.1e-32 111.5 0.0 4.7e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 AFZ81498.1 - 0.0002 20.8 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 AFZ81498.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Crystall_2 PF09076.5 AFZ81498.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin SMC_N PF02463.14 AFZ81499.1 - 6.2e-66 221.7 0.0 1.3e-33 116.1 0.0 2.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AFZ81499.1 - 4.9e-17 62.0 0.0 3.2e-16 59.3 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AFZ81499.1 - 2.3e-13 50.7 5.0 2.6e-06 27.6 0.9 3.3 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AFZ81499.1 - 2.7e-11 44.1 15.1 3.3e-10 40.6 1.0 7.0 3 2 2 5 5 5 2 AAA domain IncA PF04156.9 AFZ81499.1 - 0.00057 19.5 29.3 0.00057 19.5 20.3 7.3 3 2 5 8 8 8 2 IncA protein IFT57 PF10498.4 AFZ81499.1 - 0.00067 18.4 10.6 0.00067 18.4 7.3 5.8 3 2 2 5 5 5 2 Intra-flagellar transport protein 57 WEMBL PF05701.6 AFZ81499.1 - 0.0012 17.3 48.0 0.0012 17.3 33.3 4.3 2 2 2 4 4 4 1 Weak chloroplast movement under blue light AAA_29 PF13555.1 AFZ81499.1 - 0.0049 16.3 0.1 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 AFZ81499.1 - 0.014 14.6 33.5 0.059 12.5 3.5 5.0 3 2 2 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 AFZ81499.1 - 0.18 10.2 99.6 0.012 14.0 14.3 5.3 3 2 2 5 5 5 0 AAA domain Abhydrolase_6 PF12697.2 AFZ81500.1 - 8.3e-11 42.1 0.0 1.8e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AFZ81500.1 - 4e-09 36.3 0.0 1.2e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AFZ81500.1 - 3.4e-08 33.2 3.4 8.6e-07 28.7 0.5 3.1 2 1 1 3 3 3 1 Putative lysophospholipase FAINT PF04385.10 AFZ81500.1 - 7.8e-07 28.8 4.4 0.091 12.6 0.0 4.8 5 0 0 5 5 5 3 Domain of unknown function, DUF529 UPF0565 PF10561.4 AFZ81500.1 - 0.04 12.8 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Histone PF00125.19 AFZ81503.1 - 7.3e-19 67.6 0.0 1.1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AFZ81503.1 - 3.7e-05 23.6 0.3 7.6e-05 22.6 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 AFZ81503.1 - 0.0094 16.2 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Myb_DNA-binding PF00249.26 AFZ81505.1 - 3.3e-14 52.6 1.1 1.7e-08 34.3 0.1 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain DnaJ PF00226.26 AFZ81505.1 - 2.8e-13 49.3 0.3 1.6e-12 46.9 0.2 2.4 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-bind_6 PF13921.1 AFZ81505.1 - 9.6e-08 32.0 1.4 0.0087 16.1 0.0 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Cu2_monoox_C PF03712.10 AFZ81507.1 - 0.0014 17.9 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain RRM_1 PF00076.17 AFZ81508.1 - 2.6e-57 190.3 5.4 9.1e-17 60.4 0.1 6.9 6 1 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ81508.1 - 1.1e-40 137.4 2.8 7.5e-13 48.2 0.1 6.5 6 0 0 6 6 6 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ81508.1 - 8.8e-28 95.9 3.5 8.3e-11 41.5 0.1 6.3 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C97 PF05903.9 AFZ81510.1 - 7e-29 100.5 0.1 9.3e-29 100.1 0.1 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain AAA_14 PF13173.1 AFZ81510.1 - 0.033 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Symplekin_C PF12295.3 AFZ81511.1 - 3.3e-23 82.5 0.1 3.3e-23 82.5 0.0 3.6 5 1 0 5 5 5 1 Symplekin tight junction protein C terminal HEAT PF02985.17 AFZ81511.1 - 0.066 13.3 0.2 0.96 9.7 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat NOT2_3_5 PF04153.13 AFZ81512.1 - 1.7e-19 70.0 2.5 2.6e-19 69.4 1.7 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family PCI PF01399.22 AFZ81513.1 - 1.7e-12 47.5 0.5 1.7e-12 47.5 0.3 2.4 2 1 0 2 2 2 1 PCI domain Dynamin_N PF00350.18 AFZ81514.1 - 0.044 13.5 0.9 0.15 11.8 0.6 1.9 1 1 0 1 1 1 0 Dynamin family Histone PF00125.19 AFZ81515.1 - 8.5e-14 51.4 0.1 1e-13 51.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AFZ81515.1 - 7e-05 22.9 0.1 0.0001 22.4 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AFZ81515.1 - 0.00064 19.7 0.0 0.00093 19.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 AFZ81515.1 - 0.00068 19.5 0.0 0.00091 19.1 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T PF15511.1 AFZ81515.1 - 0.0027 17.0 0.0 0.0029 16.9 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 AFZ81515.1 - 0.024 14.3 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 AFZ81515.1 - 0.14 11.8 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TIM PF00121.13 AFZ81516.1 - 3.5e-47 160.5 0.0 5.5e-47 159.8 0.0 1.3 1 1 0 1 1 1 1 Triosephosphate isomerase DUF3436 PF11918.3 AFZ81516.1 - 0.025 14.7 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3436) EF-hand_7 PF13499.1 AFZ81517.1 - 1.3e-06 28.4 2.2 0.0004 20.4 0.0 3.9 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.1 AFZ81517.1 - 7.6e-05 22.2 0.4 0.0016 17.9 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 AFZ81517.1 - 0.00012 21.6 0.1 0.0022 17.7 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 AFZ81517.1 - 0.00032 19.7 0.1 0.002 17.2 0.0 2.4 2 0 0 2 2 2 1 EF hand RAP PF08373.5 AFZ81517.1 - 0.051 13.3 0.0 0.2 11.4 0.0 2.0 1 0 0 1 1 1 0 RAP domain EF-hand_9 PF14658.1 AFZ81517.1 - 0.064 13.1 0.0 0.44 10.4 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain WD40 PF00400.27 AFZ81518.1 - 1.1e-10 40.9 11.0 1.8e-05 24.3 0.2 5.1 5 1 0 5 5 5 3 WD domain, G-beta repeat DUF3617 PF12276.3 AFZ81518.1 - 0.0026 17.2 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3617) Cytochrom_D1 PF02239.11 AFZ81518.1 - 0.069 11.4 0.2 3.8 5.7 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF1682 PF07946.9 AFZ81519.1 - 3.8e-48 163.9 7.9 6.7e-48 163.1 5.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1682) Colicin_V PF02674.11 AFZ81519.1 - 0.083 12.7 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Colicin V production protein HCNGP PF07818.8 AFZ81520.1 - 4.7e-23 81.0 0.4 7.8e-23 80.3 0.3 1.4 1 0 0 1 1 1 1 HCNGP-like protein LicD PF04991.8 AFZ81520.1 - 0.019 15.0 0.3 0.022 14.8 0.2 1.1 1 0 0 1 1 1 0 LicD family PIN_4 PF13638.1 AFZ81520.1 - 0.11 12.5 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 PIN domain KH_1 PF00013.24 AFZ81521.1 - 7e-10 38.4 0.2 0.0016 18.0 0.1 2.6 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 AFZ81521.1 - 1.5e-05 24.5 0.2 0.022 14.4 0.0 2.6 2 0 0 2 2 2 2 KH domain WD40 PF00400.27 AFZ81523.1 - 7.4e-49 161.9 30.0 1.5e-08 34.1 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 AFZ81523.1 - 6e-05 21.3 3.8 0.14 10.2 0.5 3.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 FAT PF02259.18 AFZ81524.1 - 6.2e-14 51.7 0.6 5.5e-13 48.6 0.4 2.4 1 1 0 1 1 1 1 FAT domain oligo_HPY PF08352.7 AFZ81524.1 - 0.18 12.2 0.1 0.5 10.7 0.0 1.7 1 0 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region Peptidase_C2 PF00648.16 AFZ81525.1 - 3e-30 105.2 1.3 1.9e-25 89.5 0.5 2.8 2 1 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.17 AFZ81525.1 - 2e-16 59.9 0.5 4.7e-15 55.5 0.1 2.5 2 0 0 2 2 2 1 Calpain large subunit, domain III TIP49 PF06068.8 AFZ81526.1 - 3e-166 553.0 1.1 3.5e-166 552.8 0.7 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 AFZ81526.1 - 7.3e-10 39.1 1.6 2.9e-07 30.7 0.1 2.8 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AFZ81526.1 - 4.5e-07 30.0 0.0 4.3e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 AFZ81526.1 - 5.1e-07 28.9 0.3 9.1e-06 24.8 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AFZ81526.1 - 1.4e-05 25.2 0.1 0.0041 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 AFZ81526.1 - 0.00059 20.1 0.1 0.0011 19.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter Mg_chelatase PF01078.16 AFZ81526.1 - 0.00064 18.9 0.1 0.0062 15.7 0.1 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AFZ81526.1 - 0.00069 19.3 0.0 0.01 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 AFZ81526.1 - 0.00087 18.7 0.0 0.0044 16.4 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 AFZ81526.1 - 0.001 19.8 0.0 0.0022 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AFZ81526.1 - 0.0013 19.0 0.1 0.0037 17.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 AFZ81526.1 - 0.0018 18.1 0.0 0.047 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AFZ81526.1 - 0.0023 17.6 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 AFZ81526.1 - 0.0023 17.3 0.1 0.004 16.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AFZ81526.1 - 0.0031 16.6 0.2 0.0056 15.8 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 AFZ81526.1 - 0.0053 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 AFZ81526.1 - 0.0053 16.6 0.1 0.12 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_29 PF13555.1 AFZ81526.1 - 0.0054 16.2 0.2 0.011 15.2 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 AFZ81526.1 - 0.0077 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 AFZ81526.1 - 0.013 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DNA_pol3_delta2 PF13177.1 AFZ81526.1 - 0.017 14.7 0.0 0.061 12.9 0.0 2.0 1 1 0 1 1 1 0 DNA polymerase III, delta subunit Arch_ATPase PF01637.13 AFZ81526.1 - 0.018 14.7 0.1 0.037 13.7 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase APS_kinase PF01583.15 AFZ81526.1 - 0.021 14.5 0.1 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase UPF0079 PF02367.12 AFZ81526.1 - 0.021 14.4 0.1 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 AFZ81526.1 - 0.021 14.0 0.2 0.057 12.6 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 AFZ81526.1 - 0.034 13.6 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SE PF00437.15 AFZ81526.1 - 0.034 13.0 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DnaB_C PF03796.10 AFZ81526.1 - 0.052 12.4 0.1 0.081 11.7 0.1 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_23 PF13476.1 AFZ81526.1 - 0.098 12.9 0.1 0.17 12.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain RhoGEF PF00621.15 AFZ81527.1 - 0.14 12.0 3.8 0.063 13.1 1.1 1.5 2 0 0 2 2 2 0 RhoGEF domain RtcB PF01139.12 AFZ81528.1 - 5.1e-143 477.0 0.0 5.6e-143 476.9 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB DUF563 PF04577.9 AFZ81528.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF563) CoA_binding PF02629.14 AFZ81529.1 - 9.7e-25 86.9 2.1 3e-23 82.1 0.0 2.6 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.14 AFZ81529.1 - 3.5e-21 75.3 0.2 5.8e-21 74.6 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 AFZ81529.1 - 1e-10 41.3 0.0 1.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.17 AFZ81529.1 - 0.01 16.3 0.0 0.049 14.1 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Peripla_BP_3 PF13377.1 AFZ81529.1 - 0.12 12.4 0.0 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding protein-like domain Pkinase PF00069.20 AFZ81530.1 - 2.2e-64 217.1 0.3 2.8e-64 216.7 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ81530.1 - 4.6e-25 88.1 0.0 6.3e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AFZ81530.1 - 9.7e-09 35.3 0.0 1.1e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Aconitase_B_N PF11791.3 AFZ81530.1 - 0.003 17.3 0.0 0.029 14.1 0.0 2.0 2 0 0 2 2 2 1 Aconitate B N-terminal domain Choline_kinase PF01633.15 AFZ81530.1 - 0.0037 16.8 0.5 0.0069 15.9 0.3 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 AFZ81530.1 - 0.02 14.2 1.3 0.076 12.3 0.9 1.9 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.9 AFZ81530.1 - 0.042 12.8 0.2 0.074 12.1 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSP70 PF00012.15 AFZ81531.1 - 2.2e-245 815.2 11.9 2.6e-245 815.0 8.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AFZ81531.1 - 1.8e-22 79.3 2.3 5.5e-22 77.7 0.5 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 AFZ81531.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 AFZ81531.1 - 0.92 8.5 6.3 1.6 7.7 0.1 3.1 2 1 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 AFZ81531.1 - 1.2 8.9 10.7 1.3e+02 2.4 5.1 3.9 2 1 0 2 2 2 0 Cell division protein FtsA DUF1712 PF08217.6 AFZ81532.1 - 3.2e-12 45.5 2.0 6.5e-12 44.4 1.3 1.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1712) TPR_11 PF13414.1 AFZ81533.1 - 6.5e-13 48.1 1.0 7.5e-11 41.5 0.0 3.0 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 AFZ81533.1 - 3.4e-05 23.2 0.7 0.001 18.6 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 AFZ81533.1 - 0.0011 18.9 1.9 1.1 9.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AFZ81533.1 - 0.0049 16.6 1.4 0.047 13.6 0.0 3.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 AFZ81533.1 - 0.035 14.0 0.7 0.62 10.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.26 AFZ81534.1 - 3e-22 78.1 2.1 5.6e-22 77.2 1.5 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.15 AFZ81534.1 - 0.021 14.4 0.0 0.075 12.7 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin Acetyltransf_1 PF00583.19 AFZ81535.1 - 1.5e-13 50.5 0.0 2.3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AFZ81535.1 - 4.9e-08 33.0 1.4 4e-07 30.0 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AFZ81535.1 - 4e-05 23.6 0.0 8.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AFZ81535.1 - 0.0007 19.6 0.0 0.0042 17.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AFZ81535.1 - 0.00082 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AFZ81535.1 - 0.0012 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1129 PF06570.6 AFZ81535.1 - 0.087 12.1 0.8 0.17 11.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Hairy_orange PF07527.8 AFZ81535.1 - 0.15 11.8 1.5 0.26 11.0 0.1 2.0 2 0 0 2 2 2 0 Hairy Orange His_Phos_1 PF00300.17 AFZ81536.1 - 8.7e-45 152.6 0.0 1.1e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Abhydrolase_5 PF12695.2 AFZ81537.1 - 3e-18 65.9 0.0 4.3e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AFZ81537.1 - 7.1e-08 32.6 0.0 4.9e-07 29.8 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AFZ81537.1 - 7.2e-07 28.6 0.0 4.7e-05 22.7 0.0 2.9 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 AFZ81537.1 - 5.8e-05 22.7 0.0 0.0002 20.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 AFZ81537.1 - 0.00039 19.9 0.1 0.0031 16.9 0.1 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF818 PF05677.7 AFZ81537.1 - 0.0021 16.8 0.3 0.0033 16.2 0.2 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DUF4239 PF14023.1 AFZ81537.1 - 0.026 13.9 0.1 0.057 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) AP2 PF00847.15 AFZ81538.1 - 7.1e-06 26.0 4.4 0.0052 16.9 0.0 4.5 5 0 0 5 5 5 2 AP2 domain Sel1 PF08238.7 AFZ81540.1 - 2.9e-24 84.9 0.8 0.00031 21.2 0.0 8.9 9 0 0 9 9 9 4 Sel1 repeat TPR_6 PF13174.1 AFZ81540.1 - 1.4e-07 31.4 0.7 0.63 10.6 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 AFZ81540.1 - 1.6e-06 27.9 0.2 0.007 16.2 0.2 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 AFZ81540.1 - 8e-05 22.1 2.2 1.4 8.8 0.0 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 AFZ81540.1 - 0.00013 22.5 0.2 11 6.8 0.0 5.4 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 AFZ81540.1 - 0.0013 19.0 1.5 13 6.2 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 AFZ81540.1 - 0.0016 18.9 0.0 40 5.2 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 AFZ81540.1 - 0.0035 16.9 11.8 0.28 10.8 0.7 5.9 5 2 3 8 8 8 2 TPR repeat Apc3 PF12895.2 AFZ81540.1 - 0.12 12.5 7.9 6.3 7.0 0.0 5.3 3 3 3 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 AFZ81540.1 - 2.1 8.4 14.0 29 4.8 0.1 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ81540.1 - 5.2 7.0 15.8 7.5 6.5 0.1 7.4 7 1 0 7 7 7 0 Tetratricopeptide repeat SART-1 PF03343.8 AFZ81542.1 - 4.2e-56 190.5 33.4 7.7e-35 120.3 19.5 3.7 1 1 1 2 2 2 2 SART-1 family BSD PF03909.12 AFZ81543.1 - 2.1e-12 46.5 0.8 7.2e-09 35.2 0.2 2.8 2 0 0 2 2 2 2 BSD domain DUF964 PF06133.6 AFZ81543.1 - 0.075 13.0 0.5 0.61 10.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF964) TUDOR PF00567.19 AFZ81544.1 - 0.00021 21.1 1.9 0.00044 20.0 0.0 2.5 2 1 1 3 3 3 1 Tudor domain DUF4285 PF14113.1 AFZ81544.1 - 0.015 15.2 1.4 0.99 9.4 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4285) DUF3186 PF11382.3 AFZ81544.1 - 0.13 11.3 0.1 0.23 10.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Enolase_C PF00113.17 AFZ81545.1 - 1.9e-150 499.8 0.0 2.4e-150 499.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 AFZ81545.1 - 3.1e-53 179.2 0.0 5.2e-53 178.4 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 AFZ81545.1 - 4.9e-06 25.6 0.0 8.3e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 AFZ81545.1 - 0.0014 18.5 0.1 0.0053 16.7 0.0 2.0 2 0 0 2 2 2 1 Enolase C-terminal domain-like UPRTase PF14681.1 AFZ81545.1 - 0.021 14.0 0.0 0.052 12.7 0.0 1.6 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase Imm-NTF2 PF15655.1 AFZ81547.1 - 0.17 12.3 3.9 0.31 11.4 2.5 1.7 1 1 0 1 1 1 0 NTF2 fold immunity protein B-block_TFIIIC PF04182.7 AFZ81548.1 - 2.9e-19 68.6 9.4 5.6e-19 67.7 0.2 4.2 4 0 0 4 4 4 2 B-block binding subunit of TFIIIC TrmB PF01978.14 AFZ81548.1 - 0.00056 19.5 2.2 0.17 11.6 0.1 4.7 5 0 0 5 5 5 1 Sugar-specific transcriptional regulator TrmB Maf PF02545.9 AFZ81549.1 - 1.3e-31 109.2 0.1 1.7e-31 108.8 0.1 1.2 1 0 0 1 1 1 1 Maf-like protein eIF3_p135 PF12807.2 AFZ81550.1 - 5.4e-07 29.7 0.1 9.9e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 AFZ81550.1 - 1.4e-06 28.1 0.1 0.35 10.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 AFZ81550.1 - 0.0037 17.8 0.0 0.37 11.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 AFZ81550.1 - 0.044 13.4 1.4 0.36 10.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 AFZ81550.1 - 0.06 13.0 0.4 0.43 10.2 0.0 2.7 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 AFZ81550.1 - 0.093 12.6 0.1 0.99 9.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.24 AFZ81552.1 - 4.3e-16 58.8 0.0 7.3e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_60s PF00428.14 AFZ81553.1 - 6.3e-20 71.3 4.4 8.3e-20 70.9 3.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytochrom_C PF00034.16 AFZ81554.1 - 8e-08 33.0 0.0 1.1e-07 32.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 AFZ81554.1 - 0.0001 22.3 0.4 0.00023 21.2 0.3 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C1 PF02167.10 AFZ81554.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrom_C550 PF14495.1 AFZ81554.1 - 0.00024 20.5 0.0 0.042 13.3 0.0 2.3 2 0 0 2 2 2 2 Cytochrome c-550 domain UvrD_C PF13361.1 AFZ81555.1 - 0.029 13.8 0.4 4.4 6.6 0.1 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DUF1240 PF06836.7 AFZ81555.1 - 0.062 13.5 0.5 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) ATP-synt_ab PF00006.20 AFZ81556.1 - 8.7e-102 339.1 0.0 1.2e-101 338.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AFZ81556.1 - 1.8e-23 83.1 0.1 3.8e-23 82.1 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AFZ81556.1 - 1.7e-15 56.9 1.8 2.4e-15 56.4 0.2 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_31 PF13614.1 AFZ81556.1 - 0.019 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-UDP PF14569.1 AFZ81556.1 - 0.16 11.7 0.0 0.45 10.2 0.0 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger GYF PF02213.11 AFZ81557.1 - 3.7e-07 29.6 1.6 7.3e-07 28.6 1.1 1.5 1 0 0 1 1 1 1 GYF domain AAA_11 PF13086.1 AFZ81558.1 - 1e-72 244.5 0.0 3.4e-72 242.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 AFZ81558.1 - 1.2e-60 204.3 0.1 2.1e-60 203.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AFZ81558.1 - 7.3e-12 44.8 0.0 8.9e-07 28.5 0.0 2.7 3 0 0 3 3 3 2 Part of AAA domain Viral_helicase1 PF01443.13 AFZ81558.1 - 1.4e-06 28.0 0.1 0.0055 16.2 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 AFZ81558.1 - 1.2e-05 24.9 0.0 0.0033 17.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 AFZ81558.1 - 0.0014 18.9 1.1 0.0014 18.9 0.8 2.2 3 0 0 3 3 2 1 AAA domain UvrD_C_2 PF13538.1 AFZ81558.1 - 0.0035 17.4 0.0 3.6 7.7 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA PF00004.24 AFZ81558.1 - 0.024 14.8 0.0 0.058 13.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AFZ81558.1 - 0.1 12.7 0.1 0.97 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 AFZ81558.1 - 0.12 13.2 0.5 0.56 11.0 0.3 2.2 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 AFZ81558.1 - 0.14 11.9 0.9 1.5 8.6 0.1 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 AFZ81558.1 - 0.22 10.9 0.0 0.41 10.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.19 AFZ81559.1 - 5.4e-08 32.7 0.0 7.4e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AFZ81559.1 - 0.0015 18.6 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4413 PF14372.1 AFZ81559.1 - 0.013 15.4 0.8 0.023 14.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Acetyltransf_10 PF13673.1 AFZ81559.1 - 0.083 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SNARE PF05739.14 AFZ81560.1 - 7.3e-05 22.3 1.8 7.3e-05 22.3 1.3 2.2 1 1 1 2 2 2 1 SNARE domain COG5 PF10392.4 AFZ81560.1 - 0.0018 18.2 2.1 0.0076 16.2 1.5 2.0 1 1 0 1 1 1 1 Golgi transport complex subunit 5 Prominin PF05478.6 AFZ81560.1 - 0.0028 15.3 1.0 0.0028 15.3 0.7 1.5 2 0 0 2 2 2 1 Prominin Endotoxin_N PF03945.9 AFZ81560.1 - 0.011 15.1 1.8 0.027 13.8 0.2 1.9 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain CR6_interact PF10147.4 AFZ81560.1 - 0.048 12.9 0.7 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 APG17 PF04108.7 AFZ81560.1 - 0.14 10.9 5.6 0.59 8.8 0.9 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 Baculo_PEP_C PF04513.7 AFZ81560.1 - 0.6 9.9 15.2 0.27 11.0 6.0 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.4 AFZ81560.1 - 0.73 9.7 6.2 5.4 6.9 4.3 2.5 1 1 0 1 1 1 0 Haemolysin XhlA Tweety PF04906.8 AFZ81560.1 - 0.8 8.0 3.5 0.36 9.1 0.5 1.7 2 0 0 2 2 2 0 Tweety Phage_pRha PF09669.5 AFZ81560.1 - 1.2 9.5 5.4 11 6.4 0.2 3.1 3 0 0 3 3 3 0 Phage regulatory protein Rha (Phage_pRha) Latarcin PF10279.4 AFZ81560.1 - 2.8 8.1 5.6 4.8 7.4 1.5 2.7 2 1 0 2 2 2 0 Latarcin precursor E1_dh PF00676.15 AFZ81561.1 - 1.3e-83 280.1 0.0 1.6e-83 279.9 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component AKNA PF12443.3 AFZ81564.1 - 0.064 13.2 0.5 0.13 12.3 0.4 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor RRM_1 PF00076.17 AFZ81567.1 - 3e-11 42.8 0.0 3.9e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ81567.1 - 3.5e-09 36.4 0.0 4.9e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ81567.1 - 3.8e-07 29.8 0.0 5.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AFZ81567.1 - 0.045 13.4 0.0 0.076 12.7 0.0 1.4 1 1 0 1 1 1 0 Limkain b1 SDF PF00375.13 AFZ81568.1 - 2.4e-22 79.2 12.1 3.2e-22 78.8 8.4 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family ELF PF03317.8 AFZ81568.1 - 8.6 5.5 11.1 0.42 9.8 3.1 2.0 2 0 0 2 2 2 0 ELF protein Polyoma_agno PF01736.11 AFZ81569.1 - 0.032 13.8 0.2 0.26 10.9 0.0 2.3 2 0 0 2 2 2 0 Polyomavirus agnoprotein DUF383 PF04063.9 AFZ81569.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF383) DEAD PF00270.24 AFZ81570.1 - 1.8e-24 86.1 0.0 3.5e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ81570.1 - 1.6e-15 56.6 0.1 3.7e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain YEATS PF03366.11 AFZ81571.1 - 2.2e-26 91.3 0.0 4.5e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 YEATS family Cag12 PF13117.1 AFZ81571.1 - 0.067 13.1 1.0 0.12 12.2 0.4 1.7 1 1 0 1 1 1 0 Cag pathogenicity island protein Cag12 Osmo_CC PF08946.5 AFZ81572.1 - 0.32 11.0 5.3 13 5.8 0.2 3.9 3 1 0 3 3 3 0 Osmosensory transporter coiled coil V_ATPase_I PF01496.14 AFZ81573.1 - 3.7e-155 517.8 11.0 4.8e-155 517.4 7.6 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Vg_Tdu PF07545.9 AFZ81573.1 - 0.0091 15.4 0.0 0.028 13.8 0.0 1.8 1 0 0 1 1 1 1 Vestigial/Tondu family MMR_HSR1 PF01926.18 AFZ81574.1 - 6.7e-18 64.7 0.1 1.5e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AFZ81574.1 - 3e-05 23.8 0.2 0.12 12.2 0.0 2.6 2 0 0 2 2 2 2 Dynamin family SRPRB PF09439.5 AFZ81574.1 - 0.00021 20.5 1.2 0.00049 19.3 0.1 2.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 AFZ81574.1 - 0.00046 19.4 1.0 0.00077 18.7 0.1 1.8 2 1 0 2 2 2 1 Ferrous iron transport protein B MobB PF03205.9 AFZ81574.1 - 0.0014 18.3 0.0 0.0036 17.0 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 AFZ81574.1 - 0.0017 17.7 0.0 0.029 13.8 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.13 AFZ81574.1 - 0.0024 16.9 0.0 0.005 15.8 0.0 1.5 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 AFZ81574.1 - 0.0026 16.9 0.0 0.0056 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF947 PF06102.7 AFZ81574.1 - 0.01 15.6 1.1 0.022 14.5 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF947) AIG1 PF04548.11 AFZ81574.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family IIGP PF05049.8 AFZ81574.1 - 0.012 14.4 0.1 0.042 12.6 0.1 1.8 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Miro PF08477.8 AFZ81574.1 - 0.024 15.1 0.0 0.056 13.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein RNA_helicase PF00910.17 AFZ81574.1 - 0.038 14.1 0.0 0.092 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 AFZ81574.1 - 0.1 12.8 0.1 0.43 10.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 AFZ81574.1 - 0.16 12.1 0.5 5.4 7.1 0.0 2.7 3 1 0 3 3 3 0 AAA domain Ribosomal_L3 PF00297.17 AFZ81575.1 - 8.2e-20 71.3 1.6 1.4e-18 67.3 1.1 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 RRM_6 PF14259.1 AFZ81576.1 - 4.1e-05 23.4 0.0 0.14 12.1 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1620 PF07774.8 AFZ81577.1 - 1.1e-26 93.4 8.1 3.2e-26 91.9 5.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 AFZ81577.1 - 0.082 12.3 0.0 2.8 7.3 0.0 2.6 3 0 0 3 3 3 0 PQQ-like domain Nucleoporin_FG PF13634.1 AFZ81578.1 - 2.1e-54 182.6 291.3 5.4e-10 39.5 33.3 7.4 1 1 6 7 7 7 7 Nucleoporin FG repeat region Nucleoporin2 PF04096.9 AFZ81578.1 - 2.4e-30 105.2 0.0 3.7e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Ribosomal_S21e PF01249.13 AFZ81579.1 - 1.6e-35 120.9 0.1 1.7e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Img2 PF05046.9 AFZ81580.1 - 1.9e-20 72.8 0.0 3.2e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Peptidase_M24 PF00557.19 AFZ81581.1 - 1.2e-42 145.8 0.0 1.7e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 AFZ81581.1 - 2.2e-24 86.4 0.0 4e-22 79.1 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain eIF-3c_N PF05470.7 AFZ81582.1 - 6.9e-101 338.1 41.7 6.1e-99 331.7 28.9 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 AFZ81582.1 - 1.7e-11 44.3 0.3 1.7e-11 44.3 0.2 3.7 3 1 1 4 4 4 1 PCI domain FeoC PF09012.5 AFZ81582.1 - 0.014 15.0 0.0 0.051 13.2 0.0 2.0 1 0 0 1 1 1 0 FeoC like transcriptional regulator tRNA-synt_1 PF00133.17 AFZ81583.1 - 2.5e-184 613.6 0.0 1.2e-183 611.4 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AFZ81583.1 - 9.5e-37 126.0 0.1 2.6e-36 124.6 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AFZ81583.1 - 2e-17 62.9 2.8 6.8e-08 31.5 0.0 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 AFZ81583.1 - 5e-09 35.7 0.2 2.4e-07 30.2 0.0 2.5 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 AFZ81583.1 - 0.0014 18.7 0.5 0.0032 17.5 0.1 1.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1b PF00579.20 AFZ81583.1 - 0.0044 16.1 0.4 0.021 13.9 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) tRNA-synt_1d PF00750.14 AFZ81583.1 - 0.0072 15.1 2.6 0.74 8.5 0.0 3.3 4 0 0 4 4 4 2 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 AFZ81583.1 - 0.0098 14.5 0.2 0.18 10.4 0.0 2.7 2 1 2 4 4 4 1 tRNA synthetases class I (E and Q), catalytic domain Anthrax_toxA PF03497.11 AFZ81586.1 - 0.16 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Anthrax toxin LF subunit Rad9 PF04139.8 AFZ81587.1 - 7.3e-20 71.1 0.1 1.4e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 Rad9 RimM PF01782.13 AFZ81587.1 - 2e-14 53.2 0.0 4.3e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 RimM N-terminal domain zf-C2H2_6 PF13912.1 AFZ81587.1 - 0.063 13.1 0.4 0.12 12.2 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger F-box PF00646.28 AFZ81588.1 - 0.00042 19.8 0.1 0.0021 17.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain Cyclin_N PF00134.18 AFZ81589.1 - 0.022 14.3 0.2 0.25 10.8 0.0 2.5 2 0 0 2 2 2 0 Cyclin, N-terminal domain Ribosomal_S2 PF00318.15 AFZ81590.1 - 1.5e-43 148.4 0.2 8.5e-22 77.4 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 PPI_Ypi1 PF07491.6 AFZ81591.1 - 3.1e-16 58.7 7.7 3.7e-16 58.4 5.3 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor Phage_Gp23 PF10669.4 AFZ81593.1 - 0.011 15.8 1.5 0.011 15.8 1.1 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DNA_ligase_A_N PF04675.9 AFZ81593.1 - 0.054 13.3 3.1 0.16 11.7 2.1 1.8 1 1 0 1 1 1 0 DNA ligase N terminus DUF2570 PF10828.3 AFZ81593.1 - 2.1 8.0 8.0 0.11 12.1 0.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) DUF3824 PF12868.2 AFZ81593.1 - 5.2 8.0 9.0 1.9 9.3 4.1 1.7 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Surp PF01805.15 AFZ81594.1 - 2.1e-17 62.5 0.3 2.1e-17 62.5 0.2 1.6 2 0 0 2 2 2 1 Surp module SapB_2 PF03489.12 AFZ81594.1 - 0.064 13.2 1.4 0.17 11.9 0.0 2.4 3 0 0 3 3 3 0 Saposin-like type B, region 2 Ribosomal_S27 PF01599.14 AFZ81596.1 - 6e-22 77.2 0.8 1.2e-21 76.2 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 AFZ81596.1 - 0.03 13.7 0.0 0.072 12.4 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin family zf-CGNR PF11706.3 AFZ81596.1 - 0.031 13.7 1.1 0.069 12.6 0.8 1.6 1 0 0 1 1 1 0 CGNR zinc finger IBR PF01485.16 AFZ81596.1 - 0.032 14.1 0.4 0.056 13.3 0.3 1.5 1 0 0 1 1 1 0 IBR domain Rad60-SLD PF11976.3 AFZ81596.1 - 0.1 12.2 0.6 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like zf-U1 PF06220.7 AFZ81597.1 - 1.6e-05 24.3 0.6 3.6e-05 23.2 0.4 1.6 1 0 0 1 1 1 1 U1 zinc finger WW PF00397.21 AFZ81597.1 - 0.006 16.4 5.8 0.01 15.6 1.4 2.6 2 0 0 2 2 2 1 WW domain LON PF02190.11 AFZ81598.1 - 0.8 9.3 5.3 8.3 6.0 2.2 3.0 2 1 0 2 2 2 0 ATP-dependent protease La (LON) domain LRR_2 PF07723.8 AFZ81598.1 - 8.5 7.0 8.6 2.9 8.5 0.1 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat SAC3_GANP PF03399.11 AFZ81600.1 - 7.9e-24 84.3 1.4 7.9e-24 84.3 1.0 2.2 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DCP1 PF06058.8 AFZ81601.1 - 8.3e-31 106.5 2.1 1.6e-30 105.6 1.5 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family RNA_pol_Rpb1_3 PF04983.13 AFZ81601.1 - 0.016 14.9 3.1 0.047 13.4 0.8 2.1 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 3 Arch_ATPase PF01637.13 AFZ81602.1 - 0.00075 19.2 4.6 0.002 17.8 0.1 2.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 AFZ81602.1 - 0.0052 16.7 0.0 0.0099 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 AFZ81602.1 - 0.0061 16.2 0.0 0.019 14.6 0.0 1.8 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 AFZ81602.1 - 0.0065 16.6 0.2 0.04 14.1 0.0 2.5 2 1 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 AFZ81602.1 - 0.015 15.4 0.0 0.051 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 AFZ81602.1 - 0.028 13.6 0.0 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 AFZ81602.1 - 0.049 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 AFZ81602.1 - 0.058 13.1 0.0 11 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 AFZ81602.1 - 0.077 13.1 0.0 0.69 10.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DCX PF03607.12 AFZ81602.1 - 0.13 11.8 0.3 5.2 6.7 0.0 2.9 3 0 0 3 3 3 0 Doublecortin T2SE PF00437.15 AFZ81602.1 - 0.15 10.9 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein PIGA PF08288.7 AFZ81603.1 - 5e-33 113.3 0.0 1.2e-32 112.0 0.0 1.7 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 AFZ81603.1 - 5.9e-31 107.1 0.0 9e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AFZ81603.1 - 4.6e-15 55.7 0.0 1.1e-14 54.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 AFZ81603.1 - 9.2e-12 45.2 0.0 1.7e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 AFZ81603.1 - 9.5e-09 35.5 0.0 1.6e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 AFZ81603.1 - 9.7e-06 25.4 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Imm47 PF15586.1 AFZ81603.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Immunity protein 47 Glyco_trans_1_2 PF13524.1 AFZ81603.1 - 0.022 15.0 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 PCI PF01399.22 AFZ81605.1 - 1.2e-17 64.1 1.8 3.2e-17 62.7 0.5 2.4 2 0 0 2 2 2 1 PCI domain TFIID-31kDa PF02291.10 AFZ81606.1 - 0.014 15.1 0.5 0.045 13.5 0.3 1.9 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit SET PF00856.23 AFZ81606.1 - 0.17 12.1 0.8 0.28 11.4 0.6 1.4 1 1 0 1 1 1 0 SET domain DER1 PF04511.10 AFZ81607.1 - 2.2e-36 125.2 16.5 2.7e-36 124.9 11.5 1.1 1 0 0 1 1 1 1 Der1-like family DUF4636 PF15468.1 AFZ81607.1 - 0.25 10.7 0.5 0.49 9.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) RRM_1 PF00076.17 AFZ81608.1 - 2.2e-33 113.6 1.1 1.4e-16 59.8 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ81608.1 - 8.8e-22 76.8 0.5 7.4e-12 45.0 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ81608.1 - 1.1e-08 34.8 0.2 3.7e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AFZ81608.1 - 0.035 13.8 0.1 0.46 10.2 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif UCH PF00443.24 AFZ81609.1 - 6.9e-39 133.5 0.1 9.5e-39 133.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 AFZ81609.1 - 2.6e-08 33.1 0.1 1.5e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family UCH_1 PF13423.1 AFZ81609.1 - 1.2e-05 24.9 3.0 0.0021 17.5 2.1 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.1 AFZ81609.1 - 0.0016 18.6 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain GYF PF02213.11 AFZ81610.1 - 0.00018 21.0 0.1 0.00047 19.6 0.1 1.8 1 0 0 1 1 1 1 GYF domain Peptidase_M24 PF00557.19 AFZ81611.1 - 2.3e-37 128.5 0.0 3.5e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 EF-hand_7 PF13499.1 AFZ81612.1 - 2.4e-13 49.9 0.6 1.8e-09 37.5 0.2 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AFZ81612.1 - 3.5e-13 47.8 2.4 3.6e-07 28.9 0.2 4.0 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 AFZ81612.1 - 2.4e-12 45.6 2.4 1.2e-05 24.7 0.4 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 AFZ81612.1 - 5.3e-09 35.0 5.7 5.7e-06 25.4 0.7 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 AFZ81612.1 - 5.1e-06 25.9 0.1 0.011 15.3 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair KOW PF00467.24 AFZ81613.1 - 1.9e-08 33.6 0.8 4.5e-08 32.4 0.6 1.6 1 0 0 1 1 1 1 KOW motif DUF1900 PF08954.6 AFZ81614.1 - 1.3e-29 102.4 0.0 1.3e-28 99.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) WD40 PF00400.27 AFZ81614.1 - 2.6e-18 65.1 7.6 4e-08 32.8 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF1899 PF08953.6 AFZ81614.1 - 2e-06 27.3 0.0 6.3e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) eIF2A PF08662.6 AFZ81614.1 - 0.0021 17.8 0.0 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A VCBS PF13517.1 AFZ81614.1 - 0.096 13.0 4.3 0.2 12.0 1.0 2.9 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-RING-like PF08746.6 AFZ81615.1 - 0.1 12.5 2.5 0.12 12.3 0.4 1.9 2 0 0 2 2 2 0 RING-like domain DEAD PF00270.24 AFZ81617.1 - 8.9e-44 148.9 0.1 1.7e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AFZ81617.1 - 9.7e-22 76.6 0.0 3.4e-21 74.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ81617.1 - 0.0002 21.2 2.5 0.0011 18.8 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit tRNA-synt_1b PF00579.20 AFZ81619.1 - 9.5e-35 120.1 0.4 1.2e-34 119.7 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pkinase PF00069.20 AFZ81620.1 - 8.5e-50 169.3 0.0 1.5e-49 168.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ81620.1 - 3.1e-25 88.7 0.0 5.2e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AFZ81620.1 - 3.2e-05 23.0 0.0 5.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like G10 PF01125.12 AFZ81620.1 - 1.3 8.5 10.3 1.6 8.2 1.8 2.6 1 1 0 2 2 2 0 G10 protein DUF221 PF02714.10 AFZ81622.1 - 1.6e-08 33.8 0.8 1.6e-08 33.8 0.5 2.2 2 1 0 2 2 2 1 Domain of unknown function DUF221 DUF221 PF02714.10 AFZ81623.1 - 0.059 12.2 5.5 0.068 12.0 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF221 TFIIA_gamma_N PF02268.11 AFZ81625.1 - 0.041 13.4 0.4 0.075 12.6 0.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain WXG100 PF06013.7 AFZ81626.1 - 0.022 14.7 0.9 16 5.5 0.0 4.3 5 0 0 5 5 5 0 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.6 AFZ81626.1 - 0.21 12.0 18.8 0.25 11.7 2.4 4.3 2 2 2 4 4 4 0 Syntaxin 6, N-terminal AcylCoA_dehyd_C PF12186.3 AFZ81626.1 - 1.3 8.9 16.3 0.18 11.6 4.0 4.1 4 1 0 4 4 4 0 Acyl-CoA dehydrogenase C terminal WEMBL PF05701.6 AFZ81626.1 - 1.9 6.8 47.2 1.3 7.4 5.4 3.6 1 1 2 3 3 3 0 Weak chloroplast movement under blue light ADIP PF11559.3 AFZ81626.1 - 7.3 6.4 33.9 0.12 12.2 6.7 4.0 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Vps26 PF03643.10 AFZ81627.1 - 1.8e-85 286.0 3.5 2.1e-85 285.8 2.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Helicase_C_2 PF13307.1 AFZ81629.1 - 3.3e-50 170.3 0.1 1e-49 168.6 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 AFZ81629.1 - 4.2e-46 156.5 0.7 1.1e-45 155.1 0.5 1.8 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 AFZ81629.1 - 6e-07 29.1 0.3 0.00016 21.2 0.0 3.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 AFZ81629.1 - 0.00021 21.1 3.8 0.0059 16.4 0.0 3.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AFZ81629.1 - 0.012 15.3 0.0 0.036 13.8 0.0 1.8 1 1 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 AFZ81629.1 - 0.035 13.3 0.0 0.52 9.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein LsmAD PF06741.8 AFZ81631.1 - 5.1e-12 45.7 1.1 1.8e-11 43.9 0.8 2.1 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 AFZ81631.1 - 2.6e-06 27.2 0.0 1e-05 25.3 0.0 2.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.17 AFZ81631.1 - 0.0023 17.4 0.0 0.0067 15.9 0.0 1.7 1 0 0 1 1 1 1 LSM domain DUF2894 PF11445.3 AFZ81631.1 - 0.0095 16.2 1.4 0.0095 16.2 1.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2894) PAM2 PF07145.10 AFZ81631.1 - 0.062 12.8 3.5 0.21 11.1 2.4 2.0 1 0 0 1 1 1 0 Ataxin-2 C-terminal region MMR_HSR1 PF01926.18 AFZ81632.1 - 1.1e-15 57.6 0.1 2.4e-15 56.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AFZ81632.1 - 5e-06 26.0 0.0 0.046 13.1 0.0 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AFZ81632.1 - 7.8e-06 25.8 0.2 0.034 13.9 0.3 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 AFZ81632.1 - 0.00025 21.5 0.1 0.0074 16.7 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein AIG1 PF04548.11 AFZ81632.1 - 0.00051 19.2 0.0 0.00087 18.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.13 AFZ81632.1 - 0.00087 18.5 0.0 0.024 13.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B PduV-EutP PF10662.4 AFZ81632.1 - 0.02 14.3 0.1 0.38 10.2 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 AFZ81632.1 - 0.049 13.0 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Ras family AAA_5 PF07728.9 AFZ81632.1 - 0.078 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 AFZ81632.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MSP7_C PF12948.2 AFZ81633.1 - 0.07 13.3 0.5 0.09 13.0 0.3 1.2 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain ACDC PF14733.1 AFZ81634.1 - 3.4e-23 81.5 4.9 5.4e-23 80.9 3.4 1.3 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 AFZ81634.1 - 2.7e-14 53.0 0.8 5.1e-14 52.1 0.6 1.5 1 0 0 1 1 1 1 AP2 domain Pkinase PF00069.20 AFZ81635.1 - 1.1e-12 47.6 0.0 1.7e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 AFZ81636.1 - 2.9e-28 98.7 0.0 4.2e-26 91.6 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ81636.1 - 5.5e-20 71.5 0.0 6.6e-15 54.8 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase DUF2951 PF11166.3 AFZ81636.1 - 0.043 13.6 0.1 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Trm112p PF03966.11 AFZ81637.1 - 0.00086 19.6 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Trm112p-like protein phiKZ_IP PF12699.2 AFZ81639.1 - 0.0011 18.0 6.2 0.014 14.3 0.2 2.1 2 0 0 2 2 2 2 phiKZ-like phage internal head proteins Tweety PF04906.8 AFZ81639.1 - 0.012 14.1 1.7 0.016 13.6 0.7 1.5 1 1 0 1 1 1 0 Tweety Flagellin_C PF00700.16 AFZ81639.1 - 0.2 11.8 6.5 0.58 10.3 0.2 3.5 4 0 0 4 4 4 0 Bacterial flagellin C-terminal helical region SNARE PF05739.14 AFZ81639.1 - 0.2 11.3 7.7 0.059 13.0 1.7 2.6 3 0 0 3 3 3 0 SNARE domain Spectrin PF00435.16 AFZ81639.1 - 0.24 11.7 2.4 4.5 7.6 0.4 2.4 2 0 0 2 2 2 0 Spectrin repeat PRP38 PF03371.10 AFZ81640.1 - 8e-29 100.4 1.6 1.3e-28 99.7 1.1 1.3 1 0 0 1 1 1 1 PRP38 family Fibrillarin PF01269.12 AFZ81641.1 - 1.1e-103 345.1 0.0 1.6e-103 344.5 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 AFZ81641.1 - 0.00036 20.1 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 AFZ81641.1 - 0.089 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain LCCL PF03815.14 AFZ81642.1 - 3e-82 270.7 15.3 9.3e-26 89.6 0.1 4.6 4 0 0 4 4 4 4 LCCL domain SRCR PF00530.13 AFZ81642.1 - 1.7e-30 105.2 7.8 1.5e-14 54.1 0.5 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain PLAT PF01477.18 AFZ81642.1 - 9.6e-17 61.3 2.8 1.5e-13 51.0 0.1 3.0 3 0 0 3 3 3 2 PLAT/LH2 domain Laminin_G_3 PF13385.1 AFZ81642.1 - 5.1e-10 39.8 0.6 1.1e-09 38.7 0.0 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Rxt3 PF08642.5 AFZ81642.1 - 3.4e-07 30.5 0.0 0.083 13.1 0.0 3.4 3 0 0 3 3 3 2 Histone deacetylation protein Rxt3 SRCR_2 PF15494.1 AFZ81642.1 - 3.3e-05 24.0 1.6 0.21 11.8 0.2 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain YecR PF13992.1 AFZ81642.1 - 0.0013 18.8 1.4 1 9.6 0.2 2.7 2 0 0 2 2 2 2 YecR-like lipoprotein MmgE_PrpD PF03972.9 AFZ81642.1 - 0.036 12.2 0.0 0.055 11.6 0.0 1.1 1 0 0 1 1 1 0 MmgE/PrpD family Radical_SAM PF04055.16 AFZ81643.1 - 1.8e-11 44.4 0.0 2.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 AFZ81643.1 - 2.3e-05 24.4 0.0 7.3e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 AFZ81643.1 - 0.0047 17.0 0.0 0.0092 16.1 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3273 PF11677.3 AFZ81644.1 - 8.7e-83 277.6 8.7 1.1e-82 277.3 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Metallophos_2 PF12850.2 AFZ81645.1 - 7.5e-16 58.3 0.0 1.2e-15 57.6 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AAA_2 PF07724.9 AFZ81646.1 - 1.8e-47 161.4 0.6 8.9e-47 159.1 0.0 2.5 4 0 0 4 4 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 AFZ81646.1 - 4.6e-22 78.6 0.4 1.8e-10 41.1 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AFZ81646.1 - 7.7e-18 64.5 0.2 4.3e-12 45.9 0.0 4.0 4 1 1 5 5 4 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AFZ81646.1 - 6.4e-17 61.9 0.0 6.5e-08 32.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain ClpB_D2-small PF10431.4 AFZ81646.1 - 1.6e-16 59.9 0.0 5.2e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 AFZ81646.1 - 1e-14 54.1 0.1 6.6e-06 25.9 0.0 2.9 2 0 0 2 2 2 2 Clp amino terminal domain AAA_16 PF13191.1 AFZ81646.1 - 1.8e-09 37.8 0.0 0.017 15.1 0.0 4.0 3 1 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.21 AFZ81646.1 - 9.8e-08 31.6 0.0 4.9e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 AFZ81646.1 - 8.5e-07 28.3 0.2 0.0092 15.1 0.0 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 AFZ81646.1 - 1.7e-06 27.2 0.0 0.00065 18.8 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin AAA_17 PF13207.1 AFZ81646.1 - 2.3e-06 28.4 0.4 0.0026 18.5 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 AFZ81646.1 - 5.8e-06 26.6 0.5 0.0062 16.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain DNA_pol3_delta2 PF13177.1 AFZ81646.1 - 1.5e-05 24.6 0.3 0.27 10.8 0.0 3.5 4 0 0 4 4 3 2 DNA polymerase III, delta subunit AAA_14 PF13173.1 AFZ81646.1 - 2.3e-05 24.2 0.1 0.035 14.0 0.0 3.6 2 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 AFZ81646.1 - 2.8e-05 24.2 3.2 0.06 13.5 0.6 3.9 3 1 0 3 3 2 2 RNA helicase IstB_IS21 PF01695.12 AFZ81646.1 - 6.1e-05 22.5 0.0 0.23 10.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.7 AFZ81646.1 - 0.00026 20.1 0.1 0.1 11.6 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 AFZ81646.1 - 0.00044 19.7 0.3 0.11 11.8 0.0 3.2 2 1 1 3 3 3 1 AAA-like domain NACHT PF05729.7 AFZ81646.1 - 0.001 18.7 0.0 0.012 15.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 AFZ81646.1 - 0.0014 18.0 0.0 1.1 8.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain Torsin PF06309.6 AFZ81646.1 - 0.0015 18.3 0.0 0.0054 16.6 0.0 1.9 1 0 0 1 1 1 1 Torsin AAA_3 PF07726.6 AFZ81646.1 - 0.0016 18.0 0.3 0.33 10.5 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 AFZ81646.1 - 0.002 17.8 0.1 0.58 9.9 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 AFZ81646.1 - 0.0033 17.2 0.0 0.086 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 AFZ81646.1 - 0.0047 16.1 0.3 0.14 11.3 0.0 3.1 3 0 0 3 3 3 1 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 AFZ81646.1 - 0.012 15.5 0.2 1.8 8.5 0.0 3.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase Vps39_1 PF10366.4 AFZ81646.1 - 0.017 15.1 0.5 3.5 7.6 0.0 3.7 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 ABC_tran PF00005.22 AFZ81646.1 - 0.021 15.1 0.4 3.7 7.8 0.0 2.9 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 AFZ81646.1 - 0.024 14.1 0.1 0.92 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 AFZ81646.1 - 0.036 13.6 0.0 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain PPR_3 PF13812.1 AFZ81647.1 - 3.1e-14 51.9 4.6 0.00081 19.4 0.0 7.5 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.15 AFZ81647.1 - 1.5e-11 43.4 20.7 3.4e-05 23.5 0.2 8.1 9 0 0 9 9 9 3 PPR repeat PPR_2 PF13041.1 AFZ81647.1 - 7e-11 41.9 11.1 9.8e-06 25.4 0.0 6.7 4 3 3 7 7 7 3 PPR repeat family Phage_GPA PF05840.8 AFZ81647.1 - 0.032 12.9 0.0 0.059 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) PPR_1 PF12854.2 AFZ81647.1 - 0.043 13.2 0.2 0.49 9.9 0.1 2.5 2 0 0 2 2 2 0 PPR repeat DUF59 PF01883.14 AFZ81648.1 - 1e-06 28.6 0.0 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF59 TPT PF03151.11 AFZ81649.1 - 2e-07 30.7 11.9 1.7e-06 27.8 5.3 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 AFZ81649.1 - 0.0067 16.4 3.5 0.0067 16.4 2.4 3.4 3 1 1 4 4 4 2 EamA-like transporter family Nuc_sug_transp PF04142.10 AFZ81649.1 - 0.36 9.9 7.2 0.98 8.4 5.0 1.8 1 1 0 1 1 1 0 Nucleotide-sugar transporter EmrE PF13536.1 AFZ81649.1 - 0.87 9.8 19.6 1.6 8.9 3.2 3.8 2 2 1 3 3 3 0 Multidrug resistance efflux transporter SET PF00856.23 AFZ81650.1 - 2.7e-23 83.0 0.1 1.1e-22 81.0 0.1 2.2 1 0 0 1 1 1 1 SET domain PHD PF00628.24 AFZ81650.1 - 6.8e-10 38.4 79.7 6.4e-05 22.5 4.9 8.8 8 0 0 8 8 8 6 PHD-finger Bromodomain PF00439.20 AFZ81650.1 - 1.2e-09 37.9 0.1 4.9e-09 35.9 0.1 2.2 1 0 0 1 1 1 1 Bromodomain Ubie_methyltran PF01209.13 AFZ81651.1 - 2.7e-79 265.5 0.5 1.8e-78 262.8 0.3 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AFZ81651.1 - 1.1e-17 64.3 0.0 3.9e-17 62.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AFZ81651.1 - 8.1e-13 48.9 0.0 2.6e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AFZ81651.1 - 9.1e-13 48.0 0.0 1.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AFZ81651.1 - 1.2e-12 48.0 0.0 8.9e-12 45.2 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 AFZ81651.1 - 5.7e-11 42.4 0.0 9.6e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AFZ81651.1 - 1.4e-10 41.4 0.0 3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AFZ81651.1 - 2.1e-07 30.9 0.0 5.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 AFZ81651.1 - 0.00015 21.1 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_8 PF05148.10 AFZ81651.1 - 0.0004 20.0 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.9 AFZ81651.1 - 0.0056 16.0 0.0 0.19 11.0 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase small domain DREV PF05219.7 AFZ81651.1 - 0.034 13.0 0.0 0.069 12.0 0.0 1.7 1 1 0 1 1 1 0 DREV methyltransferase UPF0020 PF01170.13 AFZ81651.1 - 0.039 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Peptidase_C78 PF07910.8 AFZ81652.1 - 4.1e-41 140.5 0.3 1.4e-40 138.7 0.2 1.9 2 0 0 2 2 2 1 Peptidase family C78 UPF0020 PF01170.13 AFZ81653.1 - 1.8e-08 34.1 0.0 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.12 AFZ81653.1 - 0.0047 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 THUMP domain SyrA PF11089.3 AFZ81653.1 - 0.0069 16.1 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Exopolysaccharide production repressor Methyltransf_26 PF13659.1 AFZ81653.1 - 0.09 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 AFZ81654.1 - 1.8e-16 59.2 9.1 6.2e-06 25.8 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 AFZ81654.1 - 4.2e-13 49.0 0.1 8.4e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain SET PF00856.23 AFZ81655.1 - 1.1e-27 97.2 2.6 3e-27 95.8 0.7 2.6 2 1 0 2 2 2 1 SET domain PRP1_N PF06424.7 AFZ81655.1 - 0.011 16.0 2.4 0.036 14.4 1.7 1.9 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DNA_pol_B_exo1 PF03104.14 AFZ81656.1 - 1.1e-41 142.7 1.6 1.1e-41 142.7 1.1 2.9 2 1 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 AFZ81656.1 - 1.4e-18 66.9 3.9 2.4e-17 62.8 2.4 2.8 2 1 0 2 2 2 1 DNA polymerase family B DUF2136 PF09907.4 AFZ81657.1 - 0.052 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2136) Imm22 PF15592.1 AFZ81657.1 - 0.11 12.8 0.1 0.38 11.0 0.0 1.8 1 1 1 2 2 2 0 Immunity protein 22 CPW_WPC PF09717.5 AFZ81658.1 - 4.4e-31 107.2 21.0 4.7e-16 59.1 8.3 2.5 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) MU117 PF15474.1 AFZ81658.1 - 0.023 15.1 2.0 0.023 15.1 1.4 2.2 2 2 0 2 2 2 0 Meiotically up-regulated gene family MT-A70 PF05063.9 AFZ81658.1 - 0.077 12.5 0.5 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 MT-A70 Pkinase PF00069.20 AFZ81659.1 - 1.5e-61 207.8 0.0 2.2e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ81659.1 - 6.7e-29 100.7 0.0 1.7e-28 99.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AFZ81659.1 - 2e-06 26.9 0.0 2.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AFZ81659.1 - 0.0021 17.1 0.0 0.0036 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AFZ81659.1 - 0.0074 16.0 0.2 0.018 14.7 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AFZ81659.1 - 0.059 12.9 0.1 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC_tran PF00005.22 AFZ81661.1 - 2.7e-30 105.4 0.0 2.8e-16 60.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 AFZ81661.1 - 1.5e-05 25.0 0.0 0.023 14.7 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 AFZ81661.1 - 8.2e-05 22.0 0.8 0.2 11.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AFZ81661.1 - 0.00017 22.0 3.3 0.058 13.7 0.5 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 AFZ81661.1 - 0.00028 20.8 2.5 0.045 13.5 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_17 PF13207.1 AFZ81661.1 - 0.00028 21.6 0.2 0.3 11.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 AFZ81661.1 - 0.00032 20.1 0.0 0.038 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 AFZ81661.1 - 0.00039 20.0 0.2 0.097 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AFZ81661.1 - 0.00073 18.5 0.5 0.62 8.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.1 AFZ81661.1 - 0.0011 18.9 0.6 0.022 14.7 0.2 4.9 6 0 0 6 6 5 2 AAA domain AAA_18 PF13238.1 AFZ81661.1 - 0.0013 19.0 0.1 0.78 10.0 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 AFZ81661.1 - 0.0018 17.4 0.7 0.16 11.1 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ArgK PF03308.11 AFZ81661.1 - 0.0025 16.6 0.7 0.0058 15.4 0.1 1.8 2 0 0 2 2 2 1 ArgK protein Zeta_toxin PF06414.7 AFZ81661.1 - 0.004 16.2 0.2 2.5 7.1 0.1 2.6 2 0 0 2 2 2 2 Zeta toxin UPF0079 PF02367.12 AFZ81661.1 - 0.0059 16.2 0.8 0.16 11.6 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 AFZ81661.1 - 0.0064 16.6 0.0 5.7 7.0 0.0 3.1 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 AFZ81661.1 - 0.0067 15.9 0.5 0.77 9.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 AFZ81661.1 - 0.0068 16.0 0.4 2.2 7.8 0.1 2.5 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 AFZ81661.1 - 0.0082 16.6 0.1 3.9 7.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_19 PF13245.1 AFZ81661.1 - 0.0092 15.7 2.6 3.9 7.2 0.1 3.3 3 0 0 3 3 3 1 Part of AAA domain SMC_N PF02463.14 AFZ81661.1 - 0.017 14.3 0.9 0.17 11.0 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF2791 PF10923.3 AFZ81661.1 - 0.024 13.2 0.0 0.34 9.4 0.0 2.5 3 0 0 3 3 3 0 P-loop Domain of unknown function (DUF2791) MobB PF03205.9 AFZ81661.1 - 0.034 13.8 3.5 0.67 9.6 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 AFZ81661.1 - 0.036 13.9 0.7 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.12 AFZ81661.1 - 0.037 13.5 0.1 5.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 AFZ81661.1 - 0.043 13.7 0.1 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.14 AFZ81661.1 - 0.067 12.6 1.4 9.3 5.6 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 AFZ81661.1 - 0.1 12.4 0.0 6.7 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AFZ81661.1 - 0.11 11.9 0.3 11 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain NTPase_1 PF03266.10 AFZ81661.1 - 0.13 11.9 0.2 5.4 6.6 0.1 2.5 2 0 0 2 2 2 0 NTPase DEAD PF00270.24 AFZ81662.1 - 4.9e-44 149.8 0.0 7.9e-44 149.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 AFZ81662.1 - 8.9e-22 76.4 0.4 2.4e-21 75.0 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 AFZ81662.1 - 1.1e-19 70.0 0.0 2.1e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AFZ81662.1 - 0.089 12.9 0.1 0.58 10.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain KAP_NTPase PF07693.9 AFZ81662.1 - 0.35 9.8 2.6 2.6 6.9 0.1 2.7 2 1 1 3 3 3 0 KAP family P-loop domain zf-RanBP PF00641.13 AFZ81663.1 - 1e-05 24.5 1.3 2.2e-05 23.4 0.9 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Tfb4 PF03850.9 AFZ81664.1 - 5e-20 71.9 0.0 8.5e-20 71.1 0.0 1.4 1 1 0 1 1 1 1 Transcription factor Tfb4 ER_lumen_recept PF00810.13 AFZ81665.1 - 1.4e-52 178.1 13.8 2.5e-52 177.2 9.6 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 AFZ81665.1 - 0.032 13.7 0.5 0.032 13.7 0.3 4.6 3 2 2 5 5 5 0 PQ loop repeat PsbN PF02468.10 AFZ81665.1 - 0.12 12.0 0.6 0.37 10.4 0.4 1.9 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Romo1 PF10247.4 AFZ81667.1 - 2.8e-07 30.6 0.9 4.7e-07 29.9 0.6 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Proteasome PF00227.21 AFZ81668.1 - 1.8e-56 190.4 0.0 2.3e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AFZ81668.1 - 1.5e-14 52.9 0.4 2.6e-14 52.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ssl1 PF04056.9 AFZ81668.1 - 0.011 15.3 0.9 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 Ssl1-like Proteasome PF00227.21 AFZ81669.1 - 4.1e-57 192.5 0.3 5.1e-57 192.2 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AFZ81669.1 - 4.1e-14 51.5 0.0 7.9e-14 50.6 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-C3HC4 PF00097.20 AFZ81670.1 - 0.00013 21.5 17.0 0.00024 20.6 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 AFZ81670.1 - 0.0006 19.5 8.5 0.0013 18.5 5.9 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 AFZ81670.1 - 0.0015 18.1 16.5 0.0023 17.5 11.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AFZ81670.1 - 0.0041 16.9 15.8 0.0069 16.1 10.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AFZ81670.1 - 0.0063 16.5 18.9 0.011 15.6 13.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Minor_capsid_3 PF12691.2 AFZ81670.1 - 0.052 13.2 1.9 0.54 9.9 0.4 2.2 2 0 0 2 2 2 0 Minor capsid protein from bacteriophage zf-RING_5 PF14634.1 AFZ81670.1 - 0.059 13.0 16.8 0.11 12.2 11.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Gtr1_RagA PF04670.7 AFZ81670.1 - 0.16 11.1 2.2 18 4.3 0.3 3.0 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region zf-RING_4 PF14570.1 AFZ81670.1 - 4.1 7.0 12.3 7.2 6.2 8.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain A2L_zn_ribbon PF08792.5 AFZ81671.1 - 0.44 10.0 3.6 0.22 11.0 0.7 1.9 2 0 0 2 2 2 0 A2L zinc ribbon domain FtsJ PF01728.14 AFZ81672.1 - 3.7e-55 186.7 1.7 9.6e-55 185.3 0.2 2.3 3 0 0 3 3 3 1 FtsJ-like methyltransferase Spb1_C PF07780.7 AFZ81672.1 - 1.3e-53 181.7 21.7 1.3e-53 181.7 15.0 3.1 4 0 0 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.3 AFZ81672.1 - 1.2e-26 93.1 6.5 1.2e-26 93.1 4.5 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) SnAC PF14619.1 AFZ81672.1 - 0.39 10.9 0.1 0.39 10.9 0.0 3.9 4 0 0 4 4 4 0 Snf2-ATP coupling, chromatin remodelling complex ATP-synt_C PF00137.16 AFZ81673.1 - 3.6e-30 103.6 25.6 2.2e-15 56.2 4.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PsaL PF02605.10 AFZ81673.1 - 0.016 14.7 0.2 0.028 13.9 0.2 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI DNA_Packaging_2 PF11123.3 AFZ81674.1 - 0.0046 16.8 1.6 0.006 16.4 0.1 1.9 2 1 0 2 2 2 1 DNA packaging protein Peptidase_S46 PF10459.4 AFZ81674.1 - 0.021 13.2 1.7 0.026 12.9 1.2 1.2 1 1 0 1 1 1 0 Peptidase S46 Acid_PPase PF12689.2 AFZ81674.1 - 0.026 14.1 0.2 0.043 13.4 0.1 1.4 1 0 0 1 1 1 0 Acid Phosphatase 7TMR-HDED PF07697.6 AFZ81674.1 - 0.28 10.8 8.2 0.52 9.9 4.4 2.0 1 1 1 2 2 2 0 7TM-HD extracellular Sec20 PF03908.8 AFZ81674.1 - 0.52 10.0 6.9 0.087 12.5 0.4 2.3 2 1 0 2 2 2 0 Sec20 THOC7 PF05615.8 AFZ81674.1 - 0.56 10.4 5.4 0.81 9.9 1.2 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 DUF1759 PF03564.10 AFZ81674.1 - 0.71 9.6 8.1 0.21 11.3 1.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) Fib_alpha PF08702.5 AFZ81674.1 - 8.1 6.5 12.9 16 5.5 0.3 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family KH_1 PF00013.24 AFZ81676.1 - 0.017 14.7 0.0 0.059 13.0 0.0 1.9 1 0 0 1 1 1 0 KH domain HRDC PF00570.18 AFZ81676.1 - 0.022 14.4 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 HRDC domain S10_plectin PF03501.10 AFZ81677.1 - 7.2e-40 134.7 0.1 8.4e-40 134.5 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF2250 PF10007.4 AFZ81677.1 - 0.11 12.3 0.0 0.78 9.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Methyltransf_10 PF05971.7 AFZ81678.1 - 1.7e-53 181.7 1.0 1.4e-41 142.6 0.0 3.5 3 1 0 3 3 3 3 Protein of unknown function (DUF890) Methyltransf_18 PF12847.2 AFZ81678.1 - 1.5e-05 25.5 0.0 5.6e-05 23.6 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AFZ81678.1 - 0.00022 21.2 0.0 0.00063 19.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AFZ81678.1 - 0.00026 20.4 0.0 0.00049 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 AFZ81678.1 - 0.00031 20.3 0.0 0.0012 18.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 AFZ81678.1 - 0.00036 19.7 0.0 0.00067 18.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 AFZ81678.1 - 0.0038 17.6 0.0 0.086 13.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AFZ81678.1 - 0.023 15.0 0.0 0.11 12.9 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 AFZ81678.1 - 0.068 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.11 AFZ81678.1 - 0.12 11.9 0.0 0.34 10.4 0.0 1.8 1 0 0 1 1 1 0 Met-10+ like-protein RRM_1 PF00076.17 AFZ81679.1 - 3.1e-22 77.9 1.0 7.3e-21 73.5 0.1 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ81679.1 - 3.4e-19 68.5 0.5 1.4e-15 57.0 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ81679.1 - 8e-10 38.4 0.2 4.9e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TaqI_C PF12950.2 AFZ81679.1 - 0.0036 17.0 0.2 0.0095 15.6 0.1 1.7 1 0 0 1 1 1 1 TaqI-like C-terminal specificity domain DUF3901 PF13040.1 AFZ81680.1 - 0.02 14.1 2.7 0.02 14.1 1.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3901) DUF1894 PF08979.6 AFZ81680.1 - 0.072 13.1 1.9 0.11 12.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1894) DUF807 PF05660.6 AFZ81680.1 - 0.13 11.9 1.9 0.2 11.3 0.2 2.1 2 0 0 2 2 2 0 Coxiella burnetii protein of unknown function (DUF807) Reo_sigmaC PF04582.7 AFZ81680.1 - 3.8 6.6 9.1 4.9 6.2 1.0 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 AFZ81680.1 - 4.9 6.7 12.8 4.1 6.9 4.7 2.3 1 1 1 2 2 2 0 IncA protein FUN14 PF04930.10 AFZ81681.1 - 0.04 14.1 1.2 0.04 14.1 0.8 2.1 2 1 0 2 2 2 0 FUN14 family VirE_N PF08800.5 AFZ81681.1 - 0.078 12.7 0.5 0.18 11.5 0.3 1.6 1 0 0 1 1 1 0 VirE N-terminal domain DASH_Dad3 PF08656.5 AFZ81681.1 - 4.6 7.0 12.2 3.6 7.3 4.1 3.0 2 1 0 2 2 2 0 DASH complex subunit Dad3 TFIIE-A_C-term PF11521.3 AFZ81682.1 - 0.011 15.6 0.5 0.015 15.1 0.3 1.2 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha LPP20 PF02169.11 AFZ81682.1 - 0.11 12.6 0.3 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 LPP20 lipoprotein Wzz PF02706.10 AFZ81682.1 - 0.38 10.5 2.3 15 5.3 0.3 2.0 1 1 1 2 2 2 0 Chain length determinant protein Oligomerisation PF02410.10 AFZ81683.1 - 1.1e-09 38.2 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Oligomerisation domain Ribosomal_S7e PF01251.13 AFZ81684.1 - 1.7e-61 207.0 6.7 1.9e-61 206.8 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Glyco_transf_7N PF13733.1 AFZ81684.1 - 0.014 14.7 0.1 0.028 13.7 0.1 1.5 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 FCH PF00611.18 AFZ81685.1 - 0.00017 21.6 0.1 0.00082 19.5 0.1 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DDT PF02791.12 AFZ81685.1 - 0.062 13.0 0.0 0.2 11.4 0.0 1.9 1 0 0 1 1 1 0 DDT domain DnaJ PF00226.26 AFZ81686.1 - 0.00023 20.8 0.0 0.00071 19.2 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain RIO1 PF01163.17 AFZ81687.1 - 4.5e-44 150.0 0.1 4.5e-44 150.0 0.1 1.5 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.6 AFZ81687.1 - 1.7e-29 101.7 2.1 2.8e-29 101.0 0.1 2.4 3 0 0 3 3 3 1 Rio2, N-terminal APH PF01636.18 AFZ81687.1 - 1.1e-07 31.8 1.8 0.00067 19.4 0.7 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 AFZ81687.1 - 0.0055 15.7 0.1 2.3 7.2 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family V-SNARE PF05008.10 AFZ81688.1 - 0.48 10.6 2.7 0.49 10.5 0.2 2.1 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus UPF0160 PF03690.8 AFZ81689.1 - 9.2e-90 301.2 0.2 1.1e-89 300.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) SmpA_OmlA PF04355.8 AFZ81689.1 - 0.5 10.0 3.6 0.42 10.2 0.2 2.1 2 0 0 2 2 2 0 SmpA / OmlA family UPF0160 PF03690.8 AFZ81690.1 - 1e-18 67.8 0.0 1.1e-18 67.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Rad1 PF02144.11 AFZ81691.1 - 2.4e-09 36.3 1.4 4.8e-05 22.2 0.0 2.1 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 AFZ81691.1 - 0.00072 18.7 3.6 0.0011 18.1 1.1 2.0 2 0 0 2 2 2 1 Rad9 Peptidase_M22 PF00814.20 AFZ81692.1 - 4e-55 187.2 0.0 3.7e-49 167.6 0.0 2.6 2 1 0 2 2 2 2 Glycoprotease family NT5C PF06941.7 AFZ81692.1 - 0.0021 17.5 0.2 0.0098 15.4 0.1 2.0 2 0 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) BCSC_C PF05420.6 AFZ81692.1 - 0.21 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) Ribosomal_S10 PF00338.17 AFZ81693.1 - 1.1e-23 82.8 0.1 6.1e-23 80.4 0.1 2.4 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e ABC_tran PF00005.22 AFZ81694.1 - 7.5e-35 120.2 0.0 5.2e-17 62.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AFZ81694.1 - 1.3e-14 54.8 7.3 0.00021 21.3 0.0 4.4 2 2 1 3 3 3 3 AAA domain RLI PF04068.10 AFZ81694.1 - 1.9e-12 46.5 5.4 4.6e-12 45.3 3.7 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.14 AFZ81694.1 - 1.7e-08 34.0 6.9 0.00034 19.9 0.2 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 AFZ81694.1 - 6.9e-08 31.7 3.6 6.9e-08 31.7 2.5 2.3 3 0 0 3 3 1 1 4Fe-4S binding domain AAA_22 PF13401.1 AFZ81694.1 - 1.1e-07 32.0 0.0 0.00045 20.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 AFZ81694.1 - 5.6e-07 28.9 0.6 0.28 10.1 0.0 3.8 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.1 AFZ81694.1 - 2e-06 27.2 0.3 0.049 13.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 AFZ81694.1 - 1.3e-05 24.4 1.5 0.24 10.5 0.0 3.6 4 0 0 4 4 3 2 Protein of unknown function, DUF258 AAA PF00004.24 AFZ81694.1 - 6e-05 23.2 0.0 0.056 13.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AFZ81694.1 - 8e-05 22.3 0.5 0.017 14.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Fer4_6 PF12837.2 AFZ81694.1 - 8.1e-05 22.3 2.5 8.1e-05 22.3 1.7 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.10 AFZ81694.1 - 0.00014 20.7 0.0 0.12 11.0 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Fer4_21 PF14697.1 AFZ81694.1 - 0.00017 21.4 12.8 0.00033 20.4 8.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain VirE PF05272.6 AFZ81694.1 - 0.00018 21.0 0.1 0.22 10.9 0.0 2.7 2 0 0 2 2 2 1 Virulence-associated protein E AAA_5 PF07728.9 AFZ81694.1 - 0.00019 21.1 0.2 0.17 11.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 AFZ81694.1 - 0.00027 21.2 0.1 0.19 12.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AFZ81694.1 - 0.00029 20.8 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 AFZ81694.1 - 0.00035 20.9 0.8 0.015 15.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 AFZ81694.1 - 0.00043 19.9 0.4 0.058 13.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 AFZ81694.1 - 0.0011 18.8 0.2 0.07 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.2 AFZ81694.1 - 0.0011 18.7 2.5 0.0011 18.7 1.7 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain UPF0079 PF02367.12 AFZ81694.1 - 0.0014 18.2 0.0 0.03 13.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 AFZ81694.1 - 0.0015 18.6 0.0 0.9 9.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 AFZ81694.1 - 0.0021 17.5 0.1 0.73 9.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 AFZ81694.1 - 0.0024 17.3 3.0 0.095 12.1 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 AFZ81694.1 - 0.0025 17.5 0.9 0.34 10.5 0.0 2.9 3 0 0 3 3 2 1 NTPase Miro PF08477.8 AFZ81694.1 - 0.0027 18.2 0.1 0.2 12.1 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein Fer4_10 PF13237.1 AFZ81694.1 - 0.0037 17.0 1.6 0.0037 17.0 1.1 2.0 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_17 PF13207.1 AFZ81694.1 - 0.0056 17.4 2.3 2.9 8.7 0.4 2.9 2 2 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 AFZ81694.1 - 0.01 15.7 0.1 3.7 7.5 0.0 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Thymidylate_kin PF02223.12 AFZ81694.1 - 0.011 15.1 0.8 3.5 6.9 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase Fer4_3 PF12798.2 AFZ81694.1 - 0.016 15.7 4.3 0.016 15.7 3.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_16 PF13484.1 AFZ81694.1 - 0.022 15.4 0.5 0.022 15.4 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 AFZ81694.1 - 0.029 14.6 14.1 0.084 13.1 9.8 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_30 PF13604.1 AFZ81694.1 - 0.049 13.2 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 AFZ81694.1 - 0.05 13.5 0.2 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AFZ81694.1 - 0.057 13.3 0.5 11 5.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain Fer4_15 PF13459.1 AFZ81694.1 - 0.063 13.8 0.4 0.063 13.8 0.3 2.0 2 0 0 2 2 1 0 4Fe-4S single cluster domain Arch_ATPase PF01637.13 AFZ81694.1 - 0.066 12.8 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase MMR_HSR1 PF01926.18 AFZ81694.1 - 0.071 13.0 0.0 8.5 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.17 AFZ81694.1 - 0.08 11.7 0.1 8.8 5.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.1 AFZ81694.1 - 0.086 12.6 0.8 0.37 10.5 0.0 2.4 3 0 0 3 3 1 0 Part of AAA domain Fer4_7 PF12838.2 AFZ81694.1 - 0.095 13.0 15.8 0.18 12.2 10.1 2.1 2 1 0 2 2 1 0 4Fe-4S dicluster domain Septin PF00735.13 AFZ81694.1 - 0.098 11.6 0.1 1.6 7.6 0.0 2.6 3 0 0 3 3 3 0 Septin AAA_24 PF13479.1 AFZ81694.1 - 0.14 11.7 1.7 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 AFZ81694.1 - 0.14 11.0 0.0 6.7 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 AFZ81694.1 - 0.15 11.1 0.1 1.3 8.1 0.0 2.3 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Fer4_8 PF13183.1 AFZ81694.1 - 0.34 10.9 10.3 1 9.4 7.2 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_10 PF12846.2 AFZ81694.1 - 0.41 10.0 1.7 13 5.0 0.0 2.7 3 0 0 3 3 2 0 AAA-like domain PduV-EutP PF10662.4 AFZ81694.1 - 0.54 9.7 2.4 5.8 6.3 0.0 3.3 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_4 PF12800.2 AFZ81694.1 - 3.6 8.1 15.5 0.055 13.8 1.6 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain DUF947 PF06102.7 AFZ81695.1 - 1.7e-28 99.5 19.4 2.6e-28 98.9 13.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF947) PDGF_N PF04692.8 AFZ81695.1 - 6.5 7.3 7.0 2.1 8.9 1.9 2.6 2 1 0 2 2 2 0 Platelet-derived growth factor, N terminal region RAP PF08373.5 AFZ81697.1 - 9.5e-24 82.9 0.7 1.8e-23 82.0 0.1 1.8 2 0 0 2 2 2 1 RAP domain Toxin_59 PF15537.1 AFZ81697.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 59 MMtag PF10159.4 AFZ81697.1 - 0.27 11.3 0.2 0.27 11.3 0.1 1.8 2 1 0 2 2 2 0 Kinase phosphorylation protein zf-C4H2 PF10146.4 AFZ81698.1 - 0.02 14.9 6.7 0.033 14.2 4.7 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein OmpH PF03938.9 AFZ81698.1 - 0.084 12.8 2.0 0.15 11.9 1.4 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FlxA PF14282.1 AFZ81698.1 - 0.24 11.3 8.1 1.8 8.5 3.7 2.3 1 1 1 2 2 2 0 FlxA-like protein TMPIT PF07851.8 AFZ81698.1 - 0.25 10.3 2.1 0.33 9.9 1.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein Prominin PF05478.6 AFZ81698.1 - 0.32 8.4 8.0 0.36 8.3 5.6 1.0 1 0 0 1 1 1 0 Prominin DUF4094 PF13334.1 AFZ81698.1 - 0.84 10.0 5.0 0.73 10.2 1.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) DUF1664 PF07889.7 AFZ81698.1 - 1.7 8.4 5.2 7.1 6.4 1.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) HSBP1 PF06825.7 AFZ81698.1 - 2.8 7.5 5.5 5.2 6.7 0.3 3.1 3 0 0 3 3 3 0 Heat shock factor binding protein 1 FlaC_arch PF05377.6 AFZ81698.1 - 4.8 7.1 8.2 5.4 6.9 3.0 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 AFZ81698.1 - 6 6.4 7.2 8.9 5.8 5.0 1.4 1 1 0 1 1 1 0 IncA protein PH_3 PF14593.1 AFZ81699.1 - 0.0066 16.3 0.4 0.012 15.5 0.3 1.5 1 0 0 1 1 1 1 PH domain Synaptonemal_3 PF15191.1 AFZ81699.1 - 0.078 12.7 1.8 0.12 12.1 0.3 2.0 1 1 1 2 2 2 0 Synaptonemal complex central element protein 3 DUF1451 PF07295.6 AFZ81699.1 - 0.087 12.5 1.7 0.12 12.1 0.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) FliD_C PF07195.7 AFZ81699.1 - 0.11 11.7 5.6 0.28 10.4 0.4 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus FlaF PF07309.6 AFZ81699.1 - 0.12 12.2 1.3 0.73 9.7 0.9 2.1 1 1 0 1 1 1 0 Flagellar protein FlaF G-gamma PF00631.17 AFZ81699.1 - 0.18 11.5 1.8 12 5.7 0.1 2.8 2 1 1 3 3 3 0 GGL domain Prefoldin_3 PF13758.1 AFZ81699.1 - 0.35 10.6 3.2 19 5.1 1.1 3.0 2 1 0 2 2 2 0 Prefoldin subunit DUF489 PF04356.7 AFZ81699.1 - 0.41 10.2 3.1 1.4 8.4 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF489) VASP_tetra PF08776.6 AFZ81699.1 - 0.69 9.2 4.6 0.52 9.6 1.0 2.3 2 1 0 2 2 2 0 VASP tetramerisation domain DUF1640 PF07798.6 AFZ81699.1 - 1.4 8.9 8.1 0.5 10.3 0.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1640) Pox_A_type_inc PF04508.7 AFZ81699.1 - 2.7 8.0 0.0 2.7 8.0 0.0 3.7 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat DUF2443 PF10398.4 AFZ81699.1 - 9.4 6.1 9.3 8 6.3 0.4 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2443) TPR_2 PF07719.12 AFZ81700.1 - 0.023 14.5 0.4 1.2 9.2 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_polyA_pol_N PF12630.2 AFZ81700.1 - 0.27 11.3 5.8 5.2 7.2 0.5 2.9 2 1 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain NAC PF01849.13 AFZ81701.1 - 1.3e-21 75.8 0.4 3.8e-21 74.3 0.3 1.7 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 AFZ81701.1 - 0.0031 17.3 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain YL1 PF05764.8 AFZ81701.1 - 0.037 13.6 1.6 0.046 13.3 1.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein RNA_pol_Rpb2_3 PF04565.11 AFZ81702.1 - 0.53 10.0 2.6 1.2 8.9 0.1 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 3 Methyltrans_RNA PF04452.9 AFZ81704.1 - 8.9e-44 149.2 0.0 1.1e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase FAST_1 PF06743.10 AFZ81705.1 - 5.9e-09 35.5 8.8 0.00022 20.8 0.0 6.3 5 2 1 6 6 6 2 FAST kinase-like protein, subdomain 1 His_Phos_2 PF00328.17 AFZ81705.1 - 0.011 15.1 0.7 0.044 13.1 0.1 2.2 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) DUF4430 PF14478.1 AFZ81706.1 - 0.042 13.8 0.1 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) Ribosomal_S10 PF00338.17 AFZ81706.1 - 0.065 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e GnHR_trans PF12369.3 AFZ81707.1 - 0.59 10.6 4.1 0.22 11.9 0.7 1.9 2 0 0 2 2 2 0 Gonadotropin hormone receptor transmembrane region HEAT PF02985.17 AFZ81708.1 - 1.9e-07 30.5 3.6 0.0064 16.4 0.0 7.0 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.1 AFZ81708.1 - 1.6e-05 25.1 0.0 0.057 13.7 0.0 4.4 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 AFZ81708.1 - 0.00025 21.4 0.0 0.4 11.2 0.0 4.2 4 0 0 4 4 4 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 AFZ81708.1 - 0.021 15.2 5.0 0.56 10.6 0.1 4.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region B3_4 PF03483.12 AFZ81711.1 - 1.3e-19 70.3 0.0 2.4e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 AFZ81711.1 - 6.2e-19 67.5 0.0 3.7e-15 55.4 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 AFZ81711.1 - 0.0085 15.3 0.0 0.039 13.1 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) AP2 PF00847.15 AFZ81712.1 - 4.8e-08 33.0 0.6 1.4e-07 31.5 0.4 1.8 1 0 0 1 1 1 1 AP2 domain WSN PF02206.13 AFZ81712.1 - 0.0077 15.9 1.0 2.7 7.8 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function LRR_8 PF13855.1 AFZ81713.1 - 8.6e-07 28.6 3.8 5.9e-06 25.9 0.1 3.2 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 AFZ81713.1 - 4.5e-06 26.1 5.2 4.9e-05 22.8 0.7 4.4 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AFZ81713.1 - 2.6e-05 23.8 6.3 0.55 10.4 0.0 5.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 AFZ81713.1 - 0.00044 19.8 13.7 1 9.6 0.1 6.3 5 2 1 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 AFZ81713.1 - 0.32 11.3 1.7 1.1e+02 3.7 0.0 4.3 3 0 0 3 3 3 0 Leucine rich repeat PPTA PF01239.17 AFZ81714.1 - 8.2e-17 59.7 21.6 6.2e-06 25.3 0.4 5.2 5 1 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat Sec7 PF01369.15 AFZ81715.1 - 1.6e-68 230.1 3.0 4.1e-68 228.8 2.1 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 AFZ81715.1 - 2.3e-18 66.1 6.2 2.3e-18 66.1 4.3 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal EF_TS PF00889.14 AFZ81716.1 - 3e-12 46.3 0.0 5.1e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor TS UBA_4 PF14555.1 AFZ81716.1 - 0.0018 17.7 0.0 0.0033 16.9 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Peptidase_C48 PF02902.14 AFZ81717.1 - 9.9e-21 74.3 5.9 9.9e-21 74.3 4.1 2.4 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain PMI_typeI PF01238.16 AFZ81718.1 - 9.9e-49 166.2 0.0 8.8e-48 163.1 0.0 2.1 1 1 0 1 1 1 1 Phosphomannose isomerase type I Pkinase PF00069.20 AFZ81719.1 - 2.1e-38 131.9 0.0 6.5e-37 127.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AFZ81719.1 - 2.2e-11 43.3 0.0 4.2e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Gpi1 PF05024.10 AFZ81720.1 - 3.8e-23 82.1 20.4 3.8e-23 82.1 14.1 1.9 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Amidohydro_2 PF04909.9 AFZ81721.1 - 0.00016 21.3 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 AFZ81721.1 - 0.0074 15.9 0.2 0.014 15.1 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase family PRD_Mga PF08270.6 AFZ81721.1 - 0.028 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain ELFV_dehydrog PF00208.16 AFZ81722.1 - 1.9e-38 132.4 0.0 4.1e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 AFZ81722.1 - 4.3e-21 74.2 0.0 1.2e-15 56.0 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 AFZ81722.1 - 0.00021 20.8 0.0 0.00056 19.4 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF976 PF06162.7 AFZ81722.1 - 0.014 14.8 0.0 0.33 10.4 0.0 2.9 3 0 0 3 3 3 0 Caenorhabditis elegans protein of unknown function (DUF976) SNF2_N PF00176.18 AFZ81725.1 - 2e-28 99.0 0.0 4.8e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AFZ81725.1 - 4.8e-10 39.1 0.0 1.5e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AFZ81725.1 - 0.00053 19.8 0.3 0.11 12.3 0.0 3.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AFZ81725.1 - 0.0015 18.0 0.0 0.011 15.2 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AFZ81725.1 - 0.053 13.6 0.0 0.17 12.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 AFZ81725.1 - 0.056 13.2 0.0 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Flavivirus DEAD domain S1 PF00575.18 AFZ81726.1 - 1.9e-17 63.1 0.9 7.2e-08 32.4 0.0 3.1 3 0 0 3 3 3 2 S1 RNA binding domain QH-AmDH_gamma PF08992.6 AFZ81726.1 - 0.079 12.7 0.0 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, gamma subunit Fasciclin PF02469.17 AFZ81727.1 - 5.8e-10 39.2 0.0 7.6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Ribosomal_L7Ae PF01248.21 AFZ81728.1 - 4.7e-26 90.1 0.1 6.6e-26 89.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 AFZ81728.1 - 0.011 15.5 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 PELOTA_1 PF15608.1 AFZ81728.1 - 0.063 13.0 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain S-AdoMet_synt_C PF02773.11 AFZ81729.1 - 6.5e-60 200.8 0.1 1.3e-59 199.8 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 AFZ81729.1 - 4.3e-47 158.9 0.1 1.3e-46 157.4 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 AFZ81729.1 - 3e-42 142.8 1.2 6.5e-42 141.8 0.8 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Amidase PF01425.16 AFZ81730.1 - 1.4e-72 244.9 0.0 2.5e-72 244.1 0.0 1.4 1 1 0 1 1 1 1 Amidase Gemin6 PF06372.7 AFZ81730.1 - 0.014 14.6 1.9 7.9 5.7 0.0 3.5 3 1 1 4 4 4 0 Gemin6 protein zf-C3HC4_2 PF13923.1 AFZ81731.1 - 6.2e-13 48.5 9.3 9.8e-13 47.9 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AFZ81731.1 - 1.2e-12 47.4 8.5 1.9e-12 46.8 5.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AFZ81731.1 - 3.8e-12 45.6 7.7 5.9e-12 45.0 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AFZ81731.1 - 1.9e-11 43.4 5.0 3e-11 42.7 3.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AFZ81731.1 - 1.1e-10 41.0 6.6 1.7e-10 40.4 4.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 AFZ81731.1 - 2.8e-08 33.3 1.6 2.2e-07 30.4 0.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AFZ81731.1 - 3.8e-07 29.8 7.4 6.9e-07 29.0 5.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 AFZ81731.1 - 1.8e-05 24.7 6.3 3e-05 24.0 4.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 AFZ81731.1 - 4.9e-05 22.7 3.5 7.8e-05 22.1 2.4 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.7 AFZ81731.1 - 6.7e-05 22.2 0.3 9.1e-05 21.7 0.2 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_6 PF14835.1 AFZ81731.1 - 0.00044 19.9 2.5 0.00072 19.2 1.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 AFZ81731.1 - 0.0031 17.0 3.2 0.0058 16.1 2.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 AFZ81731.1 - 0.013 15.3 5.2 0.03 14.1 3.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 AFZ81731.1 - 0.046 13.3 7.9 0.17 11.4 5.5 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 AFZ81731.1 - 0.13 11.8 6.6 0.21 11.1 4.6 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-P11 PF03854.9 AFZ81731.1 - 0.22 11.0 6.8 0.4 10.1 4.7 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-CHY PF05495.7 AFZ81731.1 - 0.37 10.9 4.3 0.58 10.3 3.0 1.3 1 0 0 1 1 1 0 CHY zinc finger Baculo_RING PF05883.6 AFZ81731.1 - 2.5 7.9 5.7 6.9 6.5 3.9 1.8 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain IBR PF01485.16 AFZ81731.1 - 3 7.7 10.8 6.4 6.7 6.0 2.4 1 1 1 2 2 2 0 IBR domain RINGv PF12906.2 AFZ81731.1 - 5.2 7.1 9.3 21 5.2 6.4 2.0 1 1 0 1 1 1 0 RING-variant domain EF-hand_6 PF13405.1 AFZ81732.1 - 2e-05 24.0 4.3 0.0033 17.1 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 AFZ81732.1 - 2.8e-05 24.1 1.8 2.8e-05 24.1 1.3 1.9 1 1 1 2 2 2 1 EF-hand domain pair Vps39_1 PF10366.4 AFZ81732.1 - 0.015 15.2 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 EF-hand_1 PF00036.27 AFZ81732.1 - 0.026 13.8 0.2 0.15 11.4 0.0 2.4 2 0 0 2 2 2 0 EF hand FliS PF02561.9 AFZ81732.1 - 0.058 13.2 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Flagellar protein FliS MgtE_N PF03448.12 AFZ81732.1 - 0.06 13.6 0.1 0.092 13.0 0.1 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain EF-hand_10 PF14788.1 AFZ81732.1 - 0.062 12.9 2.0 2 8.1 0.1 2.8 1 1 2 3 3 3 0 EF hand EF-hand_8 PF13833.1 AFZ81732.1 - 0.11 12.1 2.3 0.13 11.9 0.6 1.8 1 1 1 2 2 2 0 EF-hand domain pair Ycf1 PF05758.7 AFZ81733.1 - 2 6.0 7.3 2.2 5.8 5.1 1.1 1 0 0 1 1 1 0 Ycf1 AAA PF00004.24 AFZ81735.1 - 1.3e-15 57.7 0.0 3.4e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AFZ81735.1 - 0.00019 22.2 0.0 0.00065 20.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 AFZ81735.1 - 0.001 17.8 0.0 0.0019 16.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 AFZ81735.1 - 0.0023 17.6 0.1 0.0053 16.4 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_23 PF13476.1 AFZ81735.1 - 0.0057 16.9 0.1 0.0057 16.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 AFZ81735.1 - 0.0093 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 AFZ81735.1 - 0.019 14.3 0.1 0.048 13.0 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.1 AFZ81735.1 - 0.03 13.8 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 AFZ81735.1 - 0.034 13.8 1.9 0.12 12.0 0.1 2.5 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.1 AFZ81735.1 - 0.041 14.2 0.7 0.2 11.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 AFZ81735.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 AFZ81735.1 - 0.099 11.8 0.1 0.61 9.2 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 AFZ81735.1 - 0.13 12.4 0.6 5.1 7.3 0.0 2.9 3 0 0 3 3 3 0 RNA helicase RuvB_N PF05496.7 AFZ81735.1 - 0.15 11.0 0.0 0.36 9.8 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AFZ81735.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain CRAL_TRIO PF00650.15 AFZ81736.1 - 2.2e-26 92.2 1.6 2.2e-26 92.2 1.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 AFZ81736.1 - 1.3e-06 28.4 1.9 4e-06 26.7 0.8 2.1 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Yip1 PF04893.12 AFZ81737.1 - 0.15 11.5 9.6 0.44 10.0 6.7 1.7 1 1 0 1 1 1 0 Yip1 domain LSM PF01423.17 AFZ81739.1 - 9.3e-06 25.1 0.9 4.1e-05 23.0 0.7 1.9 1 1 0 1 1 1 1 LSM domain WD40 PF00400.27 AFZ81740.1 - 2.9e-07 30.0 4.4 0.012 15.4 0.3 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat UQ_con PF00179.21 AFZ81741.1 - 6.6e-44 148.7 0.0 7.8e-44 148.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AFZ81741.1 - 0.00089 19.0 0.1 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RRM_1 PF00076.17 AFZ81742.1 - 1.9e-32 110.7 0.9 5.5e-15 54.7 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AFZ81742.1 - 3.6e-27 94.1 0.0 7e-13 48.3 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AFZ81742.1 - 3e-12 46.2 0.1 0.00017 21.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 AFZ81742.1 - 0.024 14.3 2.2 3.3 7.3 0.0 3.4 3 1 1 4 4 4 0 Suppressor of forked protein (Suf) RRM_3 PF08777.6 AFZ81742.1 - 0.053 13.3 0.0 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif Arm PF00514.18 AFZ81743.1 - 2.4e-82 268.2 0.7 2.5e-13 49.3 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 AFZ81743.1 - 2.4e-23 82.1 0.0 5.4e-10 39.4 0.0 5.0 1 1 4 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 AFZ81743.1 - 9.2e-22 76.9 0.0 2e-08 34.5 0.0 5.4 4 2 1 5 5 5 3 HEAT-like repeat HEAT PF02985.17 AFZ81743.1 - 1.8e-18 64.8 0.1 0.00011 22.0 0.0 7.6 8 0 0 8 8 8 3 HEAT repeat Arm_2 PF04826.8 AFZ81743.1 - 1.8e-09 37.0 0.0 0.052 12.6 0.0 4.8 2 1 1 4 4 4 3 Armadillo-like RICTOR_V PF14668.1 AFZ81743.1 - 7.8e-06 25.7 1.9 0.41 10.6 0.1 5.0 4 2 2 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 IBB PF01749.15 AFZ81743.1 - 1.6e-05 25.0 10.2 0.00018 21.6 7.0 2.3 1 1 0 1 1 1 1 Importin beta binding domain Proteasom_PSMB PF10508.4 AFZ81743.1 - 7.6e-05 21.1 0.1 0.011 13.9 0.0 2.4 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 AFZ81743.1 - 0.00069 19.5 0.0 3.3 7.6 0.0 4.3 3 1 2 5 5 5 1 V-ATPase subunit H Adaptin_N PF01602.15 AFZ81743.1 - 0.0008 17.8 0.0 1 7.6 0.0 2.9 1 1 0 2 2 2 2 Adaptin N terminal region HEAT_PBS PF03130.11 AFZ81743.1 - 0.0069 16.7 0.0 1.2 9.7 0.0 3.8 3 0 0 3 3 2 1 PBS lyase HEAT-like repeat Neurochondrin PF05536.6 AFZ81743.1 - 0.017 13.4 0.1 7.1 4.8 0.0 3.0 3 0 0 3 3 3 0 Neurochondrin Nucleoplasmin PF03066.10 AFZ81744.1 - 2.9e-07 30.1 1.8 3.3e-07 29.9 1.3 1.1 1 0 0 1 1 1 1 Nucleoplasmin CDC45 PF02724.9 AFZ81744.1 - 0.14 10.1 1.3 0.13 10.2 0.9 1.0 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 AFZ81744.1 - 0.62 10.3 8.6 1.1 9.5 5.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 AFZ81744.1 - 1.2 9.4 5.4 1.8 8.9 3.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2040 PF09745.4 AFZ81745.1 - 4.7e-19 68.4 18.0 9.1e-18 64.3 6.6 2.3 1 1 1 2 2 2 2 Coiled-coil domain-containing protein 55 (DUF2040) MAS20 PF02064.10 AFZ81745.1 - 0.65 9.9 7.4 2.3 8.1 0.3 2.4 1 1 1 2 2 2 0 MAS20 protein import receptor RNA_pol_Rpb5_C PF01191.14 AFZ81746.1 - 2.4e-34 116.7 0.3 4e-34 116.0 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 AFZ81746.1 - 1.1e-24 86.6 2.3 1.1e-24 86.6 0.9 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 AFZ81746.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Sof1 PF04158.9 AFZ81746.1 - 0.084 12.9 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Sof1-like domain Molybdopterin PF00384.17 AFZ81746.1 - 0.11 11.1 0.1 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin oxidoreductase WD40 PF00400.27 AFZ81747.1 - 3.6e-07 29.8 2.3 0.0088 15.8 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Rieske PF00355.21 AFZ81748.1 - 7.1e-16 57.5 0.0 1.3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 AFZ81748.1 - 3.2e-05 24.0 0.0 6.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region FAINT PF04385.10 AFZ81749.1 - 2e-13 50.0 0.6 5.4e-06 26.1 0.1 3.4 3 0 0 3 3 3 3 Domain of unknown function, DUF529 A_deaminase PF00962.17 AFZ81750.1 - 6.3e-77 258.6 0.0 7.2e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase KdpA PF03814.10 AFZ81752.1 - 0.12 10.4 0.1 0.15 10.0 0.1 1.1 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit FAINT PF04385.10 AFZ81753.1 - 1.4e-18 66.4 0.0 8.4e-06 25.5 0.0 5.1 4 1 1 5 5 5 3 Domain of unknown function, DUF529 Cytochrom_B_N_2 PF13631.1 EKX71952.1 - 2.9e-31 108.5 15.3 2.9e-31 108.5 10.6 3.1 3 1 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.12 EKX71952.1 - 2.5e-18 66.1 6.4 2.5e-18 66.1 4.4 4.0 2 1 2 5 5 5 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_N PF00033.14 EKX71952.1 - 1.1e-08 34.6 22.0 1.1e-08 34.6 15.2 2.5 2 1 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB COX1 PF00115.15 EKX71953.1 - 5.2e-119 397.7 44.8 6.1e-119 397.5 31.0 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I GTP_EFTU PF00009.22 EKX71954.1 - 3.8e-57 192.7 3.4 5.5e-57 192.2 2.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EKX71954.1 - 3.3e-29 100.9 0.1 2.1e-27 95.1 0.1 2.6 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EKX71954.1 - 1.2e-16 60.6 6.0 1.8e-16 60.0 1.3 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EKX71954.1 - 5.4e-06 26.3 0.2 1.3e-05 25.1 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EKX71954.1 - 0.0013 19.2 0.2 0.003 18.0 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein DisA_N PF02457.11 EKX71954.1 - 0.018 14.2 0.1 0.059 12.5 0.0 1.8 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding Septin PF00735.13 EKX71954.1 - 0.067 12.2 1.6 0.1 11.6 0.1 1.8 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 EKX71954.1 - 0.14 11.6 3.3 6.5 6.2 2.0 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosom_S12_S23 PF00164.20 EKX71955.1 - 6.8e-41 138.5 4.3 7.6e-41 138.3 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S5 PF00333.15 EKX71956.1 - 0.00046 19.8 0.0 0.00074 19.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF2340 PF10209.4 EKX71957.1 - 0.087 12.9 7.3 0.21 11.7 5.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) Sec20 PF03908.8 EKX71957.1 - 2.4 7.9 6.4 3.3 7.4 2.3 2.6 1 1 1 2 2 2 0 Sec20 Peptidase_C24 PF03510.9 EKX71957.1 - 2.7 8.2 7.4 0.85 9.8 2.7 1.9 1 1 1 2 2 2 0 2C endopeptidase (C24) cysteine protease family Ribosomal_L5_C PF00673.16 EKX71958.1 - 1.9e-07 30.6 0.3 1.9e-07 30.6 0.2 1.6 2 0 0 2 2 2 1 ribosomal L5P family C-terminus CRAL_TRIO_2 PF13716.1 EKX71958.1 - 0.28 11.0 7.2 0.23 11.3 4.1 1.5 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain Ribosomal_L2_C PF03947.13 EKX71959.1 - 1.6e-27 95.8 0.4 3.2e-27 94.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EKX71959.1 - 0.00068 19.5 3.7 0.0011 18.8 1.4 2.1 2 1 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain S4 PF01479.20 EKX71960.1 - 7.5e-11 41.2 0.7 1.5e-10 40.3 0.1 1.8 2 0 0 2 2 2 1 S4 domain Ribosomal_S2 PF00318.15 EKX71961.1 - 5e-18 65.1 0.0 5.9e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 LSR PF05624.9 EKX71963.1 - 0.072 12.8 1.7 0.1 12.3 1.1 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) RNA_pol_Rpb2_6 PF00562.23 EKX71964.1 - 2.9e-69 233.6 0.0 3.9e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.15 EKX71964.1 - 8.1e-10 38.8 0.1 3.4e-09 36.8 0.0 2.1 1 1 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EKX71964.1 - 8.4e-08 31.8 0.0 2.1e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 MvaI_BcnI PF15515.1 EKX71964.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 MvaI/BcnI restriction endonuclease family AAA_2 PF07724.9 EKX71965.1 - 3.9e-15 56.1 0.0 5e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EKX71965.1 - 0.00048 19.8 0.0 0.00068 19.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EKX71966.1 - 1.9e-37 128.7 0.0 4.9e-37 127.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EKX71966.1 - 9.8e-09 35.0 0.0 9.7e-08 31.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EKX71966.1 - 1.3e-07 31.2 0.0 2.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 EKX71966.1 - 6.9e-07 29.5 0.1 3.7e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EKX71966.1 - 0.00012 21.2 0.2 0.00098 18.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 EKX71966.1 - 0.00023 21.2 1.3 0.00081 19.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKX71966.1 - 0.0073 17.1 0.1 0.05 14.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EKX71966.1 - 0.018 14.0 0.0 0.034 13.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EKX71966.1 - 0.023 13.8 0.0 0.064 12.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DEAD PF00270.24 EKX71966.1 - 0.069 12.6 1.5 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.22 EKX71966.1 - 0.078 13.2 0.1 0.078 13.2 0.0 2.4 2 1 0 2 2 1 0 ABC transporter AAA_33 PF13671.1 EKX71966.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Amdo_NSP PF12475.3 EKX71967.1 - 0.22 11.4 1.3 0.35 10.7 0.3 1.8 2 0 0 2 2 2 0 Amdovirus non-structural protein DUF663 PF04950.7 EKX71969.1 - 1.1e-78 264.2 0.6 1.1e-78 264.2 0.4 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EKX71969.1 - 5.1e-26 90.0 0.0 1.9e-25 88.2 0.0 2.1 2 0 0 2 2 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EKX71969.1 - 3.7e-06 26.4 0.4 3.7e-06 26.4 0.2 3.4 4 1 0 4 4 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EKX71969.1 - 6e-05 23.1 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EKX71969.1 - 0.00013 22.1 0.1 0.01 15.9 0.0 3.2 3 0 0 3 3 3 1 RNA helicase MobB PF03205.9 EKX71969.1 - 0.00027 20.6 0.2 0.001 18.8 0.1 2.0 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EKX71969.1 - 0.0003 20.4 0.0 0.00067 19.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Miro PF08477.8 EKX71969.1 - 0.00058 20.3 1.7 0.0023 18.3 0.1 2.9 3 0 0 3 3 2 1 Miro-like protein AAA_14 PF13173.1 EKX71969.1 - 0.0013 18.5 0.7 0.0046 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EKX71969.1 - 0.0034 17.5 0.0 0.013 15.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKX71969.1 - 0.007 16.4 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EKX71969.1 - 0.012 14.8 0.0 0.027 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EKX71969.1 - 0.013 14.9 0.0 0.013 14.9 0.0 2.7 3 1 0 3 3 3 0 AAA-like domain AAA_25 PF13481.1 EKX71969.1 - 0.018 14.4 0.0 0.054 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EKX71969.1 - 0.032 13.9 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EKX71969.1 - 0.036 14.8 3.2 0.073 13.8 0.0 3.0 3 1 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 EKX71969.1 - 0.046 13.6 0.8 0.16 11.8 0.2 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EKX71969.1 - 0.056 13.7 1.3 0.26 11.6 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 EKX71969.1 - 0.075 12.9 0.7 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EKX71969.1 - 0.12 11.9 0.0 0.36 10.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EKX71969.1 - 0.6 10.4 0.0 0.6 10.4 0.0 3.7 3 1 0 3 3 3 0 AAA domain FAINT PF04385.10 EKX71970.1 - 1.5e-07 31.1 0.8 3.2e-07 30.1 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function, DUF529 EMA PF02488.10 EKX71970.1 - 0.00066 19.2 0.8 0.00081 18.9 0.6 1.1 1 0 0 1 1 1 1 Merozoite Antigen DUF4141 PF13605.1 EKX71970.1 - 0.032 13.4 0.8 0.52 9.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4141) DUF1510 PF07423.6 EKX71971.1 - 0.0031 16.9 1.6 0.0034 16.7 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Folate_carrier PF01770.13 EKX71971.1 - 0.18 10.2 0.2 0.19 10.1 0.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier Macoilin PF09726.4 EKX71971.1 - 0.35 9.1 12.4 0.38 8.9 8.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Pox_Ag35 PF03286.9 EKX71971.1 - 0.68 9.4 9.0 0.76 9.2 6.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DDRGK PF09756.4 EKX71971.1 - 1.9 7.8 12.5 2.1 7.6 8.7 1.1 1 0 0 1 1 1 0 DDRGK domain DUF2828 PF11443.3 EKX71971.1 - 2.3 6.3 7.8 2.7 6.0 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Sec62 PF03839.11 EKX71971.1 - 3.1 7.1 10.6 3.7 6.8 7.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4647 PF15504.1 EKX71971.1 - 3.4 6.4 10.5 3.6 6.3 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) BTV_NS2 PF04514.7 EKX71971.1 - 4.7 5.9 10.8 5.6 5.7 7.5 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Neur_chan_memb PF02932.11 EKX71971.1 - 9.1 6.0 6.4 11 5.8 4.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paramyxo_ncap PF00973.14 EKX71971.1 - 9.9 4.7 7.3 11 4.5 5.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein zf-CW PF07496.10 EKX71972.1 - 1.7e-16 59.6 6.9 4e-16 58.4 4.8 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger EF-hand_1 PF00036.27 EKX71973.1 - 1.1e-29 99.4 4.4 4.6e-09 34.9 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EKX71973.1 - 3.2e-26 91.2 1.5 2.6e-16 59.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EKX71973.1 - 8.3e-25 84.4 0.4 7.4e-08 31.6 0.0 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EKX71973.1 - 2.1e-23 81.6 5.7 1.4e-11 43.8 0.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EKX71973.1 - 5.3e-18 63.4 7.5 2e-06 26.8 0.1 4.8 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.1 EKX71973.1 - 3.9e-11 42.7 0.0 6e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EKX71973.1 - 0.0017 18.0 1.2 2.1 8.1 0.0 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EKX71973.1 - 0.0034 17.3 0.0 0.36 10.8 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Ribosomal_L50 PF10501.4 EKX71973.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal subunit 39S IspD PF01128.14 EKX71974.1 - 5.3e-32 111.1 0.0 8.7e-29 100.6 0.0 2.4 2 0 0 2 2 2 2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.14 EKX71974.1 - 0.014 15.0 0.0 0.052 13.1 0.0 1.9 2 0 0 2 2 2 0 Cytidylyltransferase NTP_transf_3 PF12804.2 EKX71974.1 - 0.02 14.9 0.0 0.053 13.5 0.0 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain Ribophorin_I PF04597.9 EKX71975.1 - 5.1e-42 143.8 6.3 4.1e-41 140.9 4.3 1.9 1 1 0 1 1 1 1 Ribophorin I Asp PF00026.18 EKX71976.1 - 6.7e-69 232.5 0.0 1.1e-68 231.7 0.0 1.3 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EKX71976.1 - 8e-05 22.6 0.0 0.0002 21.3 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EKX71976.1 - 0.0054 16.2 0.0 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal FAINT PF04385.10 EKX71979.1 - 0.0029 17.4 5.2 0.015 15.1 0.1 3.6 3 0 0 3 3 3 1 Domain of unknown function, DUF529 AAA_31 PF13614.1 EKX71979.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain FAINT PF04385.10 EKX71980.1 - 1.4e-08 34.4 34.7 0.00074 19.3 1.3 7.1 6 1 0 6 6 6 4 Domain of unknown function, DUF529 EpuA PF11772.3 EKX71980.1 - 0.16 11.4 0.0 0.39 10.1 0.0 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Hydrolase_3 PF08282.7 EKX71981.1 - 9.8e-40 136.7 0.0 1.2e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX71981.1 - 1.1e-06 28.1 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EKX71981.1 - 0.00019 21.6 1.0 0.01 15.9 0.7 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAINT PF04385.10 EKX71982.1 - 5.4e-20 71.0 4.3 9.5e-07 28.5 0.0 4.4 4 0 0 4 4 4 4 Domain of unknown function, DUF529 FAINT PF04385.10 EKX71983.1 - 2.9e-12 46.2 11.8 0.00065 19.5 0.0 5.6 5 1 0 5 5 5 3 Domain of unknown function, DUF529 Abhydrolase_5 PF12695.2 EKX71983.1 - 4e-10 39.6 0.0 1.2e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKX71983.1 - 1.1e-09 38.4 0.0 2.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX71983.1 - 3e-09 36.6 0.2 3.9e-08 33.0 0.1 2.5 2 0 0 2 2 2 1 Putative lysophospholipase DUF829 PF05705.9 EKX71983.1 - 0.012 15.2 0.0 0.045 13.4 0.0 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Abhydrolase_4 PF08386.5 EKX71983.1 - 0.02 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_1 PF00561.15 EKX71983.1 - 0.063 12.8 0.0 3.7 7.0 0.0 2.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EKX71983.1 - 0.071 12.5 0.1 18 4.6 0.0 3.1 4 0 0 4 4 4 0 Phospholipase/Carboxylesterase dsDNA_bind PF01984.15 EKX71985.1 - 3.8e-20 71.8 10.3 4.2e-20 71.7 7.1 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4332 PF14229.1 EKX71985.1 - 0.00033 20.6 0.7 0.00052 19.9 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) LsmAD PF06741.8 EKX71985.1 - 0.26 11.4 3.8 0.75 9.9 0.2 2.3 2 0 0 2 2 2 0 LsmAD domain DUF572 PF04502.8 EKX71985.1 - 0.46 9.6 7.1 0.48 9.5 5.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) eIF3_subunit PF08597.5 EKX71985.1 - 0.82 9.1 6.5 0.39 10.2 0.8 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit CTNNBL PF08216.6 EKX71985.1 - 1 8.9 4.9 1 8.9 0.1 2.1 1 1 1 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear Ribosomal_S27e PF01667.12 EKX71987.1 - 1.1e-23 82.5 4.8 1.4e-23 82.1 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.7 EKX71987.1 - 0.0065 15.7 0.5 0.01 15.1 0.3 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.16 EKX71987.1 - 0.0074 16.1 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 IBR domain zf-LSD1 PF06943.7 EKX71987.1 - 0.013 15.0 1.4 1.5 8.4 0.1 2.6 2 1 0 2 2 2 0 LSD1 zinc finger EMA PF02488.10 EKX71989.1 - 1.1e-68 231.4 1.0 1.3e-68 231.1 0.7 1.1 1 0 0 1 1 1 1 Merozoite Antigen Ribosomal_L24e PF01246.15 EKX71991.1 - 3e-19 68.6 2.0 5.9e-19 67.6 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e DUF4407 PF14362.1 EKX71991.1 - 0.3 9.9 2.8 0.38 9.6 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1191 PF06697.7 EKX71992.1 - 0.026 13.3 0.5 3 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) DCP2 PF05026.8 EKX71993.1 - 6e-26 90.1 0.5 4e-23 81.0 0.1 2.3 2 0 0 2 2 2 2 Dcp2, box A domain NUDIX PF00293.23 EKX71993.1 - 4.1e-16 58.8 0.0 7e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CPSase_L_D2 PF02786.12 EKX71994.1 - 4.5e-89 297.2 0.0 2.3e-65 219.8 0.0 2.6 2 1 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EKX71994.1 - 8e-43 145.0 0.0 2.3e-42 143.6 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EKX71994.1 - 1.1e-40 139.1 0.0 2.9e-40 137.7 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 EKX71994.1 - 2.2e-35 121.0 0.1 5.7e-35 119.7 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EKX71994.1 - 4.3e-30 104.0 0.0 2.5e-15 56.5 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EKX71994.1 - 3.1e-24 85.3 0.0 2.8e-15 55.9 0.0 3.4 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EKX71994.1 - 5.1e-21 75.2 0.2 3.7e-13 49.6 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EKX71994.1 - 3.9e-10 39.5 0.1 3.4e-08 33.2 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 Dala_Dala_lig_C PF07478.8 EKX71994.1 - 1.5e-08 34.2 0.0 5.9e-05 22.5 0.0 3.4 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EKX71994.1 - 4.4e-08 32.6 0.0 5e-06 25.9 0.0 2.8 2 1 0 2 2 2 1 ATP-grasp domain MGS PF02142.17 EKX71994.1 - 4.9e-06 26.3 0.1 4.5e-05 23.3 0.0 2.7 2 1 0 2 2 2 1 MGS-like domain ATP-grasp_3 PF02655.9 EKX71994.1 - 0.00063 19.6 0.1 0.48 10.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain DUF1191 PF06697.7 EKX71995.1 - 0.048 12.4 0.6 5.8 5.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Pkinase PF00069.20 EKX71996.1 - 6e-63 212.4 0.0 7.1e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX71996.1 - 2.5e-28 98.8 0.0 3.5e-28 98.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKX71996.1 - 9.8e-06 24.7 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EKX71996.1 - 1e-05 24.6 0.0 0.00017 20.6 0.0 2.1 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EKX71996.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EKX71996.1 - 0.015 14.9 0.6 0.026 14.1 0.4 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Auxin_inducible PF02519.9 EKX71996.1 - 0.028 14.4 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Auxin responsive protein DUF1664 PF07889.7 EKX71997.1 - 0.052 13.3 1.5 2.8 7.7 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MMtag PF10159.4 EKX71998.1 - 3e-20 72.0 2.2 3e-20 72.0 1.5 2.5 2 1 0 2 2 2 1 Kinase phosphorylation protein MIP-T3 PF10243.4 EKX71998.1 - 6.8 5.0 23.5 8.7 4.6 16.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 WD40 PF00400.27 EKX71999.1 - 5.5e-14 51.4 3.4 1.1e-08 34.6 0.0 5.3 5 1 1 6 6 6 3 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EKX71999.1 - 5.9e-07 29.3 1.0 0.00092 18.9 0.0 2.7 3 0 0 3 3 3 2 Transcription factor IIIC subunit delta N-term P16-Arc PF04699.9 EKX72000.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Abhydrolase_6 PF12697.2 EKX72001.1 - 7.3e-10 39.1 0.0 1.3e-09 38.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX72001.1 - 1.7e-06 27.8 0.0 2.6e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKX72001.1 - 0.00019 21.0 0.0 0.00043 19.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DALR_1 PF05746.10 EKX72003.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 DALR anticodon binding domain UPF0147 PF03685.8 EKX72005.1 - 0.029 14.2 0.7 0.23 11.3 0.1 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) Alpha_GJ PF03229.8 EKX72006.1 - 0.68 10.2 2.9 1.1 9.5 2.0 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J FleQ PF06490.6 EKX72007.1 - 0.053 13.6 0.1 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ RRM_1 PF00076.17 EKX72009.1 - 4.9e-21 74.1 0.0 4.2e-09 35.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX72009.1 - 5.8e-14 51.8 0.0 6.3e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX72009.1 - 1.4e-12 47.2 0.0 8.6e-09 35.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EKX72009.1 - 0.0042 16.6 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 Calcipressin FAINT PF04385.10 EKX72010.1 - 3.1e-17 62.1 17.5 0.00028 20.6 0.5 4.6 4 0 0 4 4 4 4 Domain of unknown function, DUF529 RED_N PF07808.8 EKX72011.1 - 3.7e-20 72.1 25.2 2.6e-19 69.4 14.2 3.0 2 1 0 2 2 2 1 RED-like protein N-terminal region V-ATPase_H_C PF11698.3 EKX72012.1 - 1.4e-45 154.0 2.6 2.2e-45 153.4 0.7 2.2 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 EKX72012.1 - 4e-39 134.5 5.9 5.9e-39 134.0 4.1 1.2 1 0 0 1 1 1 1 V-ATPase subunit H Arm_2 PF04826.8 EKX72012.1 - 0.00083 18.5 1.0 0.083 11.9 0.0 2.2 2 0 0 2 2 2 2 Armadillo-like HEAT_2 PF13646.1 EKX72012.1 - 0.0071 16.6 0.0 1.1 9.6 0.0 2.6 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.18 EKX72012.1 - 0.11 12.3 0.0 20 5.2 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat AP2 PF00847.15 EKX72013.1 - 2.1e-08 34.1 2.8 1.1e-07 31.8 0.2 2.8 2 1 0 2 2 2 1 AP2 domain DUF310 PF03750.8 EKX72014.1 - 8.2 6.6 9.6 21 5.3 1.5 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF310) Adeno_E3_CR2 PF02439.10 EKX72018.1 - 0.0033 16.9 1.0 0.0069 15.9 0.7 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF4199 PF13858.1 EKX72018.1 - 0.038 13.9 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Plasmodium_Vir PF05795.6 EKX72018.1 - 0.15 11.2 3.1 0.27 10.3 2.1 1.4 1 1 0 1 1 1 0 Plasmodium vivax Vir protein YjbE PF11106.3 EKX72018.1 - 3.1 7.8 9.7 2.8 7.9 5.4 1.8 1 1 1 2 2 2 0 Exopolysaccharide production protein YjbE ABC_tran PF00005.22 EKX72019.1 - 4.6e-32 111.1 0.0 1.6e-17 64.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EKX72019.1 - 5.2e-08 33.2 2.4 0.0033 17.4 0.0 4.0 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EKX72019.1 - 1.4e-05 24.5 1.3 0.14 11.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EKX72019.1 - 2.9e-05 24.1 0.2 0.024 14.6 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EKX72019.1 - 4.3e-05 23.8 0.2 0.31 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EKX72019.1 - 0.00011 22.9 0.0 0.093 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EKX72019.1 - 0.00014 21.0 0.3 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EKX72019.1 - 0.00018 21.9 5.0 0.039 14.2 0.7 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EKX72019.1 - 0.00038 19.9 0.0 0.069 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EKX72019.1 - 0.00098 18.9 0.1 0.23 11.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.1 EKX72019.1 - 0.0011 18.6 0.1 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EKX72019.1 - 0.0019 17.0 0.4 0.018 13.8 0.0 2.1 2 0 0 2 2 2 1 ArgK protein MMR_HSR1 PF01926.18 EKX72019.1 - 0.0021 18.0 0.2 0.38 10.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.14 EKX72019.1 - 0.0024 17.1 0.3 0.04 13.1 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EKX72019.1 - 0.0032 16.9 0.1 0.7 9.3 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EKX72019.1 - 0.0041 16.2 0.2 2.3 7.2 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_15 PF13175.1 EKX72019.1 - 0.0047 16.0 0.1 1 8.3 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain T2SE PF00437.15 EKX72019.1 - 0.0058 15.5 0.3 1.1 8.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 EKX72019.1 - 0.0081 16.6 0.1 4.5 7.7 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 EKX72019.1 - 0.0084 15.8 1.1 1.1 8.9 0.0 2.8 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EKX72019.1 - 0.01 15.6 3.2 0.11 12.2 0.1 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 AAA_22 PF13401.1 EKX72019.1 - 0.011 15.8 0.0 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EKX72019.1 - 0.034 13.1 0.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain NACHT PF05729.7 EKX72019.1 - 0.047 13.3 0.6 9.3 5.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 EKX72019.1 - 0.051 13.3 1.1 6.3 6.6 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EKX72019.1 - 0.1 12.4 0.0 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EKX72019.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 EKX72019.1 - 0.14 11.7 0.7 4.8 6.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EKX72019.1 - 0.15 11.4 0.2 18 4.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 EKX72019.1 - 1.5 8.2 3.5 10 5.5 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_pol_L_2 PF13656.1 EKX72026.1 - 9e-20 69.9 0.0 1.3e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EKX72026.1 - 0.011 14.8 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain NIF PF03031.13 EKX72028.1 - 2.4e-51 173.5 0.7 3.5e-51 173.0 0.5 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase UQ_con PF00179.21 EKX72029.1 - 1.3e-15 57.0 0.0 1.6e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DnaJ PF00226.26 EKX72030.1 - 7.5e-16 57.6 2.4 7.5e-16 57.6 1.7 2.1 2 0 0 2 2 2 1 DnaJ domain DUF3850 PF12961.2 EKX72030.1 - 0.077 12.9 1.7 0.93 9.5 0.1 2.5 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3850) FAINT PF04385.10 EKX72031.1 - 4.1e-21 74.6 5.2 1.2e-07 31.4 0.0 4.9 4 1 0 4 4 4 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX72031.1 - 8.6e-12 45.4 0.0 2.5e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX72031.1 - 6.9e-10 38.8 0.0 1.9e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX72031.1 - 8.9e-07 28.6 0.2 8.1e-06 25.5 0.1 2.4 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EKX72031.1 - 4.2e-05 23.2 0.0 0.00017 21.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EKX72031.1 - 8.9e-05 22.0 0.1 0.0031 17.0 0.0 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EKX72031.1 - 0.0079 15.4 0.1 1.9 7.6 0.0 2.9 3 0 0 3 3 3 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 EKX72031.1 - 0.067 12.7 0.0 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase FAINT PF04385.10 EKX72032.1 - 2e-73 242.2 93.0 7e-06 25.8 1.2 20.8 21 0 0 21 21 21 18 Domain of unknown function, DUF529 TruB-C_2 PF09157.6 EKX72032.1 - 0.51 10.2 0.0 1.2 9.0 0.0 1.6 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal Aldo_ket_red PF00248.16 EKX72033.1 - 1.1e-61 208.1 0.0 1.3e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LON PF02190.11 EKX72034.1 - 1e-07 31.8 0.3 2e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain DNA_RNApol_7kD PF03604.8 EKX72035.1 - 1.5e-16 59.5 3.3 2.1e-16 59.0 2.3 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 EKX72035.1 - 0.00032 20.4 0.2 0.00038 20.2 0.1 1.1 1 0 0 1 1 1 1 Double zinc ribbon A2L_zn_ribbon PF08792.5 EKX72035.1 - 0.0016 17.8 1.9 0.19 11.2 0.0 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain HypA PF01155.14 EKX72035.1 - 0.0024 17.5 0.2 0.0026 17.4 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family zf-ISL3 PF14690.1 EKX72035.1 - 0.0028 17.6 1.4 0.026 14.5 0.1 2.1 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 GFA PF04828.9 EKX72035.1 - 0.0056 16.6 0.5 0.96 9.4 0.1 2.1 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-C4_Topoisom PF01396.14 EKX72035.1 - 0.013 14.9 0.5 4.2 6.9 0.1 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger TF_Zn_Ribbon PF08271.7 EKX72035.1 - 0.015 14.5 1.0 2.8 7.3 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding TFIIS_C PF01096.13 EKX72035.1 - 0.017 14.7 0.2 3.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) YhfH PF14149.1 EKX72035.1 - 0.029 14.1 1.4 6 6.7 0.3 2.2 1 1 1 2 2 2 0 YhfH-like protein DUF2296 PF10058.4 EKX72035.1 - 0.036 13.8 2.5 0.26 11.0 0.0 2.3 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) DUF2197 PF09963.4 EKX72035.1 - 0.037 13.9 1.1 5.7 6.9 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-dskA_traR PF01258.12 EKX72035.1 - 0.04 13.6 1.2 0.065 12.9 0.8 1.4 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger Prok-RING_1 PF14446.1 EKX72035.1 - 0.041 13.6 0.3 0.051 13.3 0.2 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF35_N PF12172.3 EKX72035.1 - 0.052 13.4 0.3 1.5 8.8 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ribbon_3 PF13248.1 EKX72035.1 - 0.053 12.7 3.1 0.53 9.5 2.5 2.0 1 1 1 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EKX72035.1 - 0.065 13.1 1.6 0.15 12.0 1.1 1.6 1 1 0 1 1 1 0 Zinc ribbon domain UPF0547 PF10571.4 EKX72035.1 - 0.073 12.7 2.5 0.14 11.8 1.7 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 EKX72035.1 - 0.1 12.1 3.4 1.2 8.7 2.4 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EKX72035.1 - 0.14 11.9 2.9 1.4 8.8 0.3 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain RRN7 PF11781.3 EKX72035.1 - 0.18 11.2 4.6 3.7 7.1 0.2 2.1 1 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 RNA_POL_M_15KD PF02150.11 EKX72035.1 - 0.23 11.1 1.7 0.63 9.7 1.1 1.8 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-HIT PF04438.11 EKX72035.1 - 0.41 10.3 2.4 1 9.0 1.6 1.7 1 1 0 1 1 1 0 HIT zinc finger zinc_ribbon_5 PF13719.1 EKX72035.1 - 0.93 9.1 3.0 1 9.0 0.2 2.0 1 1 1 2 2 2 0 zinc-ribbon domain zf-LSD1 PF06943.7 EKX72035.1 - 3 7.5 5.4 17 5.0 3.8 2.0 1 1 0 1 1 1 0 LSD1 zinc finger Zn_ribbon_recom PF13408.1 EKX72035.1 - 3.5 7.9 9.8 1.9 8.8 1.8 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF2688 PF10892.3 EKX72035.1 - 3.9 7.2 6.0 12 5.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) zf-C2H2_6 PF13912.1 EKX72035.1 - 5.4 7.0 5.2 5.2 7.1 0.1 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger PUB PF09409.5 EKX72036.1 - 4.1e-11 42.4 1.2 4.1e-11 42.4 0.8 2.0 2 0 0 2 2 2 1 PUB domain DMPK_coil PF08826.5 EKX72037.1 - 7.4 6.5 7.8 0.75 9.7 2.4 1.6 2 0 0 2 2 2 0 DMPK coiled coil domain like FAINT PF04385.10 EKX72038.1 - 1.7e-13 50.1 6.6 2.6e-10 40.0 1.3 3.2 3 0 0 3 3 3 2 Domain of unknown function, DUF529 ATE_C PF04377.10 EKX72038.1 - 0.05 13.6 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus CENP-I PF07778.6 EKX72038.1 - 0.072 11.2 0.0 0.092 10.9 0.0 1.1 1 0 0 1 1 1 0 Mis6 FAINT PF04385.10 EKX72040.1 - 2.2e-09 36.9 3.9 3.9e-09 36.2 2.7 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 U3_assoc_6 PF08640.6 EKX72041.1 - 2.2e-16 59.3 2.9 5e-16 58.2 2.0 1.6 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 WBS_methylT PF12589.3 EKX72042.1 - 2e-16 60.2 3.3 3e-16 59.6 2.3 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EKX72042.1 - 1.8e-10 41.1 0.0 3.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKX72042.1 - 1.6e-07 31.0 0.1 2.4e-07 30.4 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKX72042.1 - 3.6e-05 24.1 0.0 7.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKX72042.1 - 3.8e-05 23.9 0.1 9.5e-05 22.7 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKX72042.1 - 0.00021 21.0 0.0 0.0003 20.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKX72042.1 - 0.00048 20.6 0.0 0.0008 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EKX72042.1 - 0.0052 15.9 0.1 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6_N4_Mtase PF01555.13 EKX72042.1 - 0.007 15.8 0.1 0.042 13.3 0.0 2.0 2 1 0 2 2 2 1 DNA methylase MetW PF07021.7 EKX72042.1 - 0.0091 15.3 0.0 0.045 13.1 0.1 1.9 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW PCMT PF01135.14 EKX72042.1 - 0.0092 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EKX72042.1 - 0.016 14.3 0.3 0.032 13.2 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase TPMT PF05724.6 EKX72042.1 - 0.028 13.8 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.9 EKX72042.1 - 0.044 13.1 0.1 0.077 12.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EKX72042.1 - 0.099 12.6 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EKX72042.1 - 0.1 12.2 0.1 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Chromo PF00385.19 EKX72045.1 - 8.5e-21 73.3 3.2 5.1e-14 51.6 0.0 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_S10 PF00338.17 EKX72046.1 - 0.00078 19.2 0.2 0.0012 18.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e AFG1_ATPase PF03969.11 EKX72047.1 - 7.4e-71 238.8 0.1 1.7e-67 227.7 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA PF00004.24 EKX72047.1 - 1.2e-06 28.7 0.0 3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 EKX72047.1 - 0.0028 17.3 0.1 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial dnaA protein IstB_IS21 PF01695.12 EKX72047.1 - 0.0074 15.7 0.0 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 EKX72047.1 - 0.0099 16.0 1.2 0.034 14.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EKX72047.1 - 0.011 15.4 0.1 0.059 13.0 0.1 2.1 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EKX72047.1 - 0.013 15.4 0.1 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cnl2_NKP2 PF09447.5 EKX72047.1 - 0.035 13.7 0.1 1.6 8.4 0.0 2.7 2 0 0 2 2 2 0 Cnl2/NKP2 family protein NACHT PF05729.7 EKX72047.1 - 0.046 13.3 0.1 0.37 10.4 0.1 2.2 1 1 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EKX72047.1 - 0.053 13.2 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EKX72047.1 - 0.099 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EKX72047.1 - 0.11 12.6 0.1 0.71 10.0 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Ribosomal_L17 PF01196.14 EKX72048.1 - 1.2e-21 77.0 0.6 1.6e-21 76.6 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 Ribosomal_L18e PF00828.14 EKX72049.1 - 5.7e-14 52.5 2.3 1.7e-12 47.8 0.4 3.5 2 2 0 2 2 2 1 Ribosomal protein L18e/L15 Sulfotransfer_1 PF00685.22 EKX72049.1 - 0.0092 15.2 1.9 0.034 13.4 1.3 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Archease PF01951.11 EKX72050.1 - 5.9e-46 155.8 1.2 8.2e-46 155.3 0.8 1.2 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) EMA PF02488.10 EKX72053.1 - 9.9e-105 349.5 11.2 1.1e-104 349.3 7.7 1.0 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 EKX72053.1 - 0.0025 17.6 1.0 0.21 11.4 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72054.1 - 2.1e-11 43.5 0.4 8.3e-07 28.7 0.2 3.0 2 1 0 3 3 3 2 Domain of unknown function, DUF529 Fil_haemagg_2 PF13332.1 EKX72055.1 - 0.049 13.4 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Haemagluttinin repeat FAINT PF04385.10 EKX72057.1 - 8.3e-14 51.2 5.8 8.1e-05 22.4 0.3 4.0 3 1 1 4 4 4 3 Domain of unknown function, DUF529 Methylase_S PF01420.14 EKX72057.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain RRM_5 PF13893.1 EKX72059.1 - 1.6e-10 40.6 0.0 0.00074 19.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKX72059.1 - 2.3e-10 39.9 0.1 0.00057 19.4 0.1 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX72059.1 - 3.7e-08 33.2 0.1 0.0047 16.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1343 PF07075.6 EKX72059.1 - 0.0028 16.5 0.0 0.0047 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1343) MIP-T3 PF10243.4 EKX72059.1 - 0.0095 14.4 3.3 0.011 14.1 2.3 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 EKX72059.1 - 0.015 15.0 38.8 0.034 13.8 26.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) NTP_transferase PF00483.18 EKX72060.1 - 1.8e-11 43.7 0.0 7.5e-11 41.7 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EKX72060.1 - 1e-08 35.3 0.0 5.4e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EKX72060.1 - 4e-06 26.0 3.1 0.00018 20.8 0.4 2.8 1 1 1 2 2 2 1 Bacterial transferase hexapeptide (six repeats) KAP PF05804.7 EKX72060.1 - 0.013 13.4 0.1 0.023 12.6 0.1 1.3 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Pentapeptide_3 PF13576.1 EKX72060.1 - 0.017 15.0 0.7 1.5 8.7 0.0 3.2 3 1 1 4 4 4 0 Pentapeptide repeats (9 copies) potato_inhibit PF00280.13 EKX72060.1 - 0.044 13.9 1.7 1.5 9.0 0.0 3.7 5 0 0 5 5 5 0 Potato inhibitor I family Hexapep_2 PF14602.1 EKX72060.1 - 1.3 8.6 3.9 17 5.0 1.2 2.8 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase FAST_1 PF06743.10 EKX72061.1 - 0.00099 18.7 3.3 0.3 10.8 0.1 4.5 4 0 0 4 4 4 2 FAST kinase-like protein, subdomain 1 Glyco_transf_20 PF00982.16 EKX72062.1 - 3.9e-96 322.4 0.0 1.3e-95 320.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EKX72062.1 - 5.5e-40 136.7 0.0 1.8e-39 135.0 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase CBM_20 PF00686.14 EKX72062.1 - 8.5e-13 47.7 0.1 3.8e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 Starch binding domain Hydrolase_3 PF08282.7 EKX72062.1 - 0.0083 15.7 0.1 0.073 12.6 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DELLA PF12041.3 EKX72062.1 - 0.026 14.1 0.3 0.06 13.0 0.2 1.5 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal RabGAP-TBC PF00566.13 EKX72063.1 - 3.2e-53 180.3 0.6 4e-53 180.0 0.4 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CAMSAP_CKK PF08683.6 EKX72064.1 - 0.012 15.2 0.2 0.032 13.9 0.0 1.7 1 1 1 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated ROF PF07073.7 EKX72064.1 - 0.085 12.8 0.2 16 5.5 0.0 2.6 1 1 2 3 3 3 0 Modulator of Rho-dependent transcription termination (ROF) PAP_central PF04928.12 EKX72064.1 - 0.1 11.3 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain eIF-1a PF01176.14 EKX72065.1 - 7e-06 25.3 0.3 1e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PBP_sp32 PF07222.7 EKX72065.1 - 0.024 13.8 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Sec_GG PF07549.9 EKX72065.1 - 0.04 13.1 0.0 0.076 12.2 0.0 1.5 1 0 0 1 1 1 0 SecD/SecF GG Motif Ribosomal_60s PF00428.14 EKX72065.1 - 5.9 7.3 7.8 10 6.6 5.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3546 PF12066.3 EKX72066.1 - 7.1e-19 67.8 7.8 1.5e-18 66.8 4.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 EKX72066.1 - 0.0051 16.3 0.1 0.018 14.6 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 EKX72066.1 - 0.0059 16.8 0.5 0.013 15.7 0.4 1.5 1 0 0 1 1 1 1 Arsenite-resistance protein 2 zf-C2H2_4 PF13894.1 EKX72066.1 - 0.0083 16.3 1.1 0.031 14.6 0.8 2.1 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.2 EKX72066.1 - 0.039 14.1 0.4 0.09 13.0 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EKX72066.1 - 1.5 9.3 6.7 0.1 12.9 0.9 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type COG4 PF08318.7 EKX72067.1 - 4.4e-16 58.5 3.6 8.2e-14 51.1 2.5 2.5 1 1 0 1 1 1 1 COG4 transport protein Metal_hydrol PF10118.4 EKX72067.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase PseudoU_synth_1 PF01416.15 EKX72069.1 - 3.9e-33 114.0 0.1 1.5e-19 70.3 0.1 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase UBACT PF02134.16 EKX72070.1 - 8.5e-13 47.6 0.0 1.4e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EKX72070.1 - 0.00012 21.3 0.8 0.0002 20.6 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site ThiF PF00899.16 EKX72070.1 - 0.0049 16.6 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family EMA PF02488.10 EKX72071.1 - 5e-63 212.8 7.1 6.2e-63 212.5 4.9 1.0 1 0 0 1 1 1 1 Merozoite Antigen Nepo_coat PF03391.10 EKX72071.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, central domain FAINT PF04385.10 EKX72071.1 - 8.3 6.3 9.8 13 5.6 3.4 3.1 2 1 0 2 2 2 0 Domain of unknown function, DUF529 RVT_1 PF00078.22 EKX72073.1 - 3e-34 118.2 0.1 5.1e-34 117.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAINT PF04385.10 EKX72074.1 - 3e-08 33.3 0.3 0.0019 18.0 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72074.1 - 4.4e-05 23.0 1.7 0.019 14.4 0.4 2.3 2 0 0 2 2 2 2 Merozoite Antigen 4HB_MCP_1 PF12729.2 EKX72074.1 - 0.54 9.5 4.7 2.5 7.3 1.0 2.2 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction FAINT PF04385.10 EKX72075.1 - 4.1e-44 148.3 11.0 3.1e-08 33.3 0.0 5.6 5 0 0 5 5 5 5 Domain of unknown function, DUF529 EMA PF02488.10 EKX72075.1 - 2.2e-08 33.9 21.1 5.3e-06 26.0 6.7 3.8 2 1 2 4 4 4 3 Merozoite Antigen Saf-Nte_pilin PF09460.5 EKX72075.1 - 7.8e-05 22.4 0.7 0.29 10.9 0.0 3.5 3 1 0 3 3 3 2 Saf-pilin pilus formation protein ABC_tran PF00005.22 EKX72076.1 - 8.6e-32 110.3 0.0 1.1e-17 64.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EKX72076.1 - 1.8e-06 28.1 8.8 0.023 14.6 0.0 4.7 6 0 0 6 6 5 2 AAA domain AAA_18 PF13238.1 EKX72076.1 - 7.3e-06 26.3 0.0 0.16 12.3 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EKX72076.1 - 7.8e-06 25.9 0.1 0.0071 16.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 EKX72076.1 - 4.2e-05 23.9 3.7 0.15 12.3 0.6 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EKX72076.1 - 5.9e-05 22.5 0.7 0.096 12.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EKX72076.1 - 0.0001 21.8 0.0 0.13 11.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain ArgK PF03308.11 EKX72076.1 - 0.00013 20.8 0.4 0.00038 19.3 0.0 1.8 2 0 0 2 2 2 1 ArgK protein AAA_30 PF13604.1 EKX72076.1 - 0.00015 21.4 0.1 0.039 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EKX72076.1 - 0.00021 20.4 0.2 0.38 9.8 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 EKX72076.1 - 0.00039 21.2 0.0 0.13 13.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EKX72076.1 - 0.00051 19.2 0.3 0.053 12.6 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EKX72076.1 - 0.00096 18.8 0.4 0.35 10.5 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EKX72076.1 - 0.0011 17.9 1.1 0.86 8.4 0.0 2.5 3 0 0 3 3 2 2 Type II/IV secretion system protein Dynamin_N PF00350.18 EKX72076.1 - 0.0042 16.9 0.3 0.49 10.2 0.0 2.5 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 EKX72076.1 - 0.0043 16.5 0.2 1.7 8.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Fer4_NifH PF00142.13 EKX72076.1 - 0.0048 16.1 0.1 2.2 7.3 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF87 PF01935.12 EKX72076.1 - 0.0072 16.1 1.6 0.059 13.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 EKX72076.1 - 0.0081 16.6 0.1 5.3 7.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_19 PF13245.1 EKX72076.1 - 0.0089 15.7 1.4 2.4 7.9 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EKX72076.1 - 0.0094 16.0 0.1 4.8 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EKX72076.1 - 0.01 15.5 0.4 4.9 6.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.14 EKX72076.1 - 0.011 15.0 0.4 0.22 10.7 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EKX72076.1 - 0.011 15.6 0.2 0.18 11.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.17 EKX72076.1 - 0.014 14.2 0.1 0.13 11.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 EKX72076.1 - 0.019 14.5 2.1 0.46 10.1 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EKX72076.1 - 0.02 14.6 0.0 9.7 5.8 0.0 2.6 3 0 0 3 3 2 0 Archaeal ATPase AAA_15 PF13175.1 EKX72076.1 - 0.025 13.6 3.9 6.4 5.7 0.0 3.9 5 0 0 5 5 4 0 AAA ATPase domain cobW PF02492.14 EKX72076.1 - 0.029 13.8 1.7 3.7 6.9 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 EKX72076.1 - 0.038 12.6 0.2 3.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 EKX72076.1 - 0.049 13.5 0.1 4.1 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EKX72076.1 - 0.058 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EKX72076.1 - 0.11 11.9 0.3 4.1 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain NTPase_1 PF03266.10 EKX72076.1 - 0.11 12.1 0.2 11 5.7 0.1 2.4 2 0 0 2 2 2 0 NTPase DnaB_C PF03796.10 EKX72076.1 - 0.13 11.0 0.0 3.3 6.5 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain SRP54 PF00448.17 EKX72076.1 - 0.23 10.8 0.4 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF2791 PF10923.3 EKX72076.1 - 0.25 9.8 0.0 2.2 6.8 0.0 2.0 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) FAINT PF04385.10 EKX72078.1 - 1.6e-07 31.0 0.0 0.033 14.0 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function, DUF529 DUF3721 PF12518.3 EKX72078.1 - 0.0063 16.0 0.9 0.011 15.3 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function Frataxin_Cyay PF01491.11 EKX72078.1 - 0.023 14.4 0.0 0.32 10.8 0.0 2.4 2 0 0 2 2 2 0 Frataxin-like domain Choline_kinase PF01633.15 EKX72079.1 - 2.8e-38 131.5 0.0 4.3e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EKX72079.1 - 1.3e-13 51.2 0.0 2.2e-13 50.5 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EKX72079.1 - 9.2e-05 21.7 0.2 0.00016 20.9 0.2 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase F5_F8_type_C PF00754.20 EKX72080.1 - 9 6.1 11.2 0.17 11.7 0.3 3.0 4 0 0 4 4 4 0 F5/8 type C domain FAINT PF04385.10 EKX72082.1 - 1.6e-14 53.4 1.5 1.1e-06 28.3 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function, DUF529 TBP PF00352.16 EKX72085.1 - 1.9e-59 197.0 0.4 5.2e-29 99.4 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) MIF4G PF02854.14 EKX72086.1 - 2.3e-21 76.1 0.5 2.3e-21 76.1 0.3 1.9 2 0 0 2 2 2 1 MIF4G domain FAINT PF04385.10 EKX72087.1 - 0.0076 16.0 0.3 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function, DUF529 Pex14_N PF04695.8 EKX72089.1 - 0.89 9.6 4.1 9.5 6.2 0.2 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_21 PF13304.1 EKX72091.1 - 0.001 19.1 0.0 0.001 19.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain PPR_2 PF13041.1 EKX72091.1 - 0.0037 17.2 0.0 0.024 14.6 0.0 2.1 1 1 1 2 2 2 2 PPR repeat family AfsA PF03756.8 EKX72091.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain C1_3 PF07649.7 EKX72093.1 - 0.23 11.5 0.9 0.47 10.5 0.6 1.5 1 0 0 1 1 1 0 C1-like domain FAINT PF04385.10 EKX72094.1 - 4.6e-17 61.6 0.5 1.4e-09 37.7 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72094.1 - 4.3e-05 23.1 6.5 0.0021 17.5 2.7 2.1 2 0 0 2 2 2 2 Merozoite Antigen FAINT PF04385.10 EKX72096.1 - 0.027 14.3 0.8 0.12 12.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function, DUF529 Amidohydro_4 PF13147.1 EKX72096.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.4 2 0 0 2 2 2 0 Amidohydrolase DUF1281 PF06924.6 EKX72098.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) Peptidase_C1 PF00112.18 EKX72099.1 - 3e-36 125.3 0.8 6.9e-36 124.1 0.1 1.9 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKX72099.1 - 0.00024 21.3 0.3 0.00046 20.4 0.2 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF1510 PF07423.6 EKX72099.1 - 0.022 14.1 21.7 0.35 10.2 15.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1628 PF07790.6 EKX72099.1 - 1.4 9.7 3.2 6.1 7.6 2.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) DUF4175 PF13779.1 EKX72099.1 - 2.2 5.8 18.5 3.6 5.1 12.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Gastrin PF00918.12 EKX72099.1 - 4.7 8.0 10.1 0.86 10.4 0.7 2.5 1 1 1 2 2 2 0 Gastrin/cholecystokinin family Herpes_LMP1 PF05297.6 EKX72099.1 - 6.7 5.5 14.0 11 4.8 9.7 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) EMA PF02488.10 EKX72101.1 - 0.0018 17.8 1.4 0.015 14.7 0.1 2.0 2 0 0 2 2 2 1 Merozoite Antigen FAINT PF04385.10 EKX72101.1 - 0.0067 16.2 0.4 0.018 14.8 0.3 1.8 1 1 0 1 1 1 1 Domain of unknown function, DUF529 FG-GAP PF01839.18 EKX72101.1 - 0.032 13.9 2.7 1.6 8.4 1.7 2.5 2 0 0 2 2 2 0 FG-GAP repeat VCBS PF13517.1 EKX72101.1 - 1.9 8.9 10.7 9.8 6.6 4.5 2.7 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FAINT PF04385.10 EKX72102.1 - 1.1e-15 57.2 4.0 3.7e-07 29.8 0.7 3.8 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX72102.1 - 1.9e-15 57.3 0.0 4e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX72102.1 - 1.2e-09 38.1 0.0 2.9e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX72102.1 - 4.8e-08 32.7 0.1 3.3e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 Putative lysophospholipase PGAP1 PF07819.8 EKX72102.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.7 EKX72102.1 - 0.017 14.4 0.2 0.092 12.0 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 EKX72102.1 - 0.057 12.9 0.0 0.24 10.9 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Shugoshin_N PF07558.6 EKX72104.1 - 0.0031 17.1 3.6 0.0031 17.1 2.5 2.9 2 1 1 3 3 2 1 Shugoshin N-terminal coiled-coil region DivIC PF04977.10 EKX72104.1 - 0.016 14.6 1.4 0.016 14.6 0.9 3.7 3 1 0 4 4 4 0 Septum formation initiator Herpes_BLRF2 PF05812.7 EKX72104.1 - 0.059 13.1 0.8 0.059 13.1 0.5 2.8 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF2353 PF09789.4 EKX72104.1 - 0.072 12.3 16.3 0.025 13.8 6.6 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF4200 PF13863.1 EKX72104.1 - 0.14 12.0 18.6 0.14 12.1 1.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Cep57_CLD_2 PF14197.1 EKX72104.1 - 0.28 11.1 16.3 0.098 12.6 6.9 3.0 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF3373 PF11853.3 EKX72104.1 - 0.55 8.7 3.5 0.88 8.0 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Allexi_40kDa PF05549.6 EKX72104.1 - 0.74 9.0 6.2 0.33 10.1 2.7 1.5 1 1 0 2 2 2 0 Allexivirus 40kDa protein DUF1192 PF06698.6 EKX72104.1 - 0.92 9.3 8.4 1.5 8.6 0.0 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF1192) SlyX PF04102.7 EKX72104.1 - 0.97 9.8 4.9 2.1 8.7 0.5 3.2 2 1 1 3 3 3 0 SlyX DUF1843 PF08898.5 EKX72104.1 - 2 8.5 5.3 0.78 9.8 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Herpes_UL6 PF01763.11 EKX72104.1 - 2 6.4 10.4 0.66 8.0 4.7 1.8 1 1 1 2 2 2 0 Herpesvirus UL6 like DUF972 PF06156.8 EKX72104.1 - 2.5 8.4 17.7 0.45 10.8 3.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) CDC37_N PF03234.9 EKX72104.1 - 3.2 8.0 13.9 4 7.7 9.2 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF904 PF06005.7 EKX72104.1 - 3.3 8.0 29.4 2.9 8.2 0.5 4.5 2 2 1 3 3 3 0 Protein of unknown function (DUF904) Syntaxin_2 PF14523.1 EKX72104.1 - 3.7 7.6 14.9 0.2 11.7 5.2 2.5 2 1 1 3 3 3 0 Syntaxin-like protein IncA PF04156.9 EKX72104.1 - 5.3 6.5 18.2 2.1 7.8 8.2 2.4 1 1 2 3 3 3 0 IncA protein Atg14 PF10186.4 EKX72104.1 - 7.5 5.4 16.7 2.9 6.7 9.4 1.8 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EKX72104.1 - 8.6 5.2 14.9 1.7 7.5 7.8 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 FAINT PF04385.10 EKX72107.1 - 2e-12 46.7 0.1 6.6e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72107.1 - 0.0073 15.8 0.0 0.025 14.0 0.0 1.8 1 1 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 EKX72108.1 - 1.8e-05 24.5 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72110.1 - 6.3e-17 61.1 10.5 9.2e-06 25.4 0.2 4.1 3 2 0 3 3 3 3 Domain of unknown function, DUF529 CpeS PF09367.5 EKX72110.1 - 0.0081 16.0 1.6 0.092 12.6 0.4 2.5 3 0 0 3 3 3 1 CpeS-like protein FAINT PF04385.10 EKX72111.1 - 1.7e-18 66.2 1.2 1.2e-07 31.4 0.0 4.0 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX72111.1 - 1.7e-13 50.9 0.0 4.2e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX72111.1 - 4.4e-11 42.7 0.0 1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX72111.1 - 3.9e-09 36.2 1.1 8.5e-08 31.9 0.3 2.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EKX72111.1 - 0.00022 20.9 0.0 0.00066 19.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKX72111.1 - 0.0011 18.2 1.5 0.028 13.6 0.1 2.6 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EKX72111.1 - 0.0032 17.0 0.1 0.015 14.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 EKX72111.1 - 0.031 13.6 0.0 0.073 12.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) FAINT PF04385.10 EKX72112.1 - 1.8e-09 37.3 1.0 0.00082 19.1 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF4110 PF13422.1 EKX72112.1 - 0.092 12.5 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) Sugar_tr PF00083.19 EKX72113.1 - 3.4e-60 203.9 33.1 4.2e-60 203.6 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKX72113.1 - 4.5e-12 45.3 34.5 4.6e-12 45.3 18.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EKX72113.1 - 5e-05 21.7 2.4 5e-05 21.7 1.6 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FAINT PF04385.10 EKX72115.1 - 7.2e-09 35.3 7.8 9.4e-05 22.1 0.6 2.7 2 1 1 3 3 3 2 Domain of unknown function, DUF529 Ras PF00071.17 EKX72116.1 - 3.2e-56 189.1 0.2 3.9e-56 188.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKX72116.1 - 3e-18 66.4 0.1 6.2e-18 65.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKX72116.1 - 2.5e-14 52.8 0.1 3.4e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKX72116.1 - 0.00027 20.1 0.1 0.00035 19.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKX72116.1 - 0.016 14.6 0.1 0.057 12.8 0.0 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKX72116.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase FAINT PF04385.10 EKX72117.1 - 0.14 11.9 2.8 0.73 9.7 0.1 3.4 2 2 1 3 3 3 0 Domain of unknown function, DUF529 RRM_1 PF00076.17 EKX72118.1 - 2.7e-10 39.7 0.0 4e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX72118.1 - 6.7e-10 38.8 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3760 PF12586.3 EKX72118.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3760) DUF1764 PF08576.5 EKX72119.1 - 3e-21 76.0 2.9 3.7e-21 75.8 2.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) LRS4 PF10422.4 EKX72119.1 - 0.39 10.0 4.7 0.52 9.6 3.3 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 UPF0020 PF01170.13 EKX72120.1 - 5.6e-12 45.6 0.0 7.2e-11 41.9 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EKX72120.1 - 2.9e-08 33.7 0.0 4.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EKX72120.1 - 2.3e-05 23.9 0.0 0.056 12.9 0.0 2.5 2 0 0 2 2 2 2 DNA methylase SF3a60_bindingd PF12108.3 EKX72120.1 - 0.013 15.0 1.6 0.028 13.9 0.1 2.1 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain TP_methylase PF00590.15 EKX72121.1 - 1e-25 90.7 0.0 1.5e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases ADK PF00406.17 EKX72122.1 - 4.2e-52 176.0 0.0 5.2e-52 175.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EKX72122.1 - 8.1e-13 47.8 0.0 1.6e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EKX72122.1 - 4.1e-05 23.4 0.0 8.8e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKX72122.1 - 7.2e-05 23.5 0.0 0.00014 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKX72122.1 - 0.00086 19.6 0.4 0.0033 17.7 0.1 2.1 2 1 0 2 2 2 1 AAA domain DAP3 PF10236.4 EKX72122.1 - 0.0069 15.3 0.0 0.067 12.1 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 Homez PF11569.3 EKX72122.1 - 0.015 14.3 0.1 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Zeta_toxin PF06414.7 EKX72122.1 - 0.024 13.7 0.0 0.09 11.8 0.0 1.9 2 1 0 2 2 2 0 Zeta toxin RHH_1 PF01402.16 EKX72122.1 - 0.087 12.7 0.0 11 6.0 0.0 2.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family AAA_28 PF13521.1 EKX72122.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain FAINT PF04385.10 EKX72123.1 - 2.2e-51 171.5 39.5 2.9e-08 33.4 0.2 10.9 10 1 0 10 10 10 10 Domain of unknown function, DUF529 DUF2510 PF10708.4 EKX72123.1 - 0.23 10.9 1.5 23 4.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2510) zf-C2H2_jaz PF12171.3 EKX72124.1 - 1.7e-05 24.8 6.8 0.019 15.1 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EKX72124.1 - 9.3e-05 22.5 4.2 0.23 11.8 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EKX72124.1 - 0.012 15.8 3.8 0.17 12.2 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 EKX72124.1 - 0.02 14.5 0.3 0.02 14.5 0.2 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.2 EKX72124.1 - 0.046 13.9 2.8 2.8 8.2 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type LIM PF00412.17 EKX72124.1 - 0.068 13.2 4.1 0.13 12.3 2.8 1.4 1 0 0 1 1 1 0 LIM domain zf-Di19 PF05605.7 EKX72124.1 - 0.083 13.0 3.1 2 8.6 0.9 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EKX72124.1 - 0.11 12.5 4.8 4.1 7.5 2.4 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EKX72124.1 - 0.22 11.5 5.5 0.27 11.1 0.3 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger TFIIS_C PF01096.13 EKX72124.1 - 0.3 10.7 2.5 2.5 7.8 0.0 2.9 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-C4_ClpX PF06689.8 EKX72124.1 - 0.68 9.4 3.4 0.78 9.3 1.4 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger GidB PF02527.10 EKX72125.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DER1 PF04511.10 EKX72126.1 - 0.1 12.0 0.1 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Der1-like family HA2 PF04408.18 EKX72127.1 - 5.3e-28 97.0 0.9 1.6e-26 92.2 0.0 2.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EKX72127.1 - 1.2e-23 83.0 0.0 2.9e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EKX72127.1 - 5.4e-14 51.8 0.0 2.1e-13 49.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EKX72127.1 - 5.3e-06 26.6 0.0 1.8e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EKX72127.1 - 2.4e-05 23.8 1.0 9.3e-05 21.9 0.1 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 EKX72127.1 - 0.00099 18.0 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EKX72127.1 - 0.034 14.1 0.5 0.63 10.0 0.0 3.1 4 0 0 4 4 4 0 AAA ATPase domain AAA_19 PF13245.1 EKX72127.1 - 0.066 12.9 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EKX72127.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family DIM1 PF02966.11 EKX72128.1 - 6.8e-63 210.1 0.8 8.1e-63 209.8 0.6 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EKX72128.1 - 0.026 14.2 0.1 0.036 13.7 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin DUF2205 PF10224.4 EKX72129.1 - 3.1e-05 23.4 0.6 5.6e-05 22.6 0.4 1.4 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) BLOC1_2 PF10046.4 EKX72129.1 - 0.00029 20.9 0.5 0.00058 19.9 0.4 1.5 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 EKX72129.1 - 0.0017 18.6 1.2 0.0039 17.4 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF904) ADIP PF11559.3 EKX72129.1 - 0.0027 17.6 0.8 0.0044 16.9 0.6 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 EKX72129.1 - 0.0037 17.0 3.2 0.0071 16.1 2.2 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Filament PF00038.16 EKX72129.1 - 0.012 15.1 0.3 0.018 14.5 0.2 1.2 1 0 0 1 1 1 0 Intermediate filament protein DivIC PF04977.10 EKX72129.1 - 0.015 14.7 0.7 0.032 13.6 0.5 1.5 1 0 0 1 1 1 0 Septum formation initiator TBPIP PF07106.8 EKX72129.1 - 0.015 14.8 1.0 0.015 14.8 0.7 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 EKX72129.1 - 0.017 13.0 0.1 0.022 12.6 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.6 EKX72129.1 - 0.018 14.8 1.1 0.028 14.2 0.8 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) UPF0184 PF03670.8 EKX72129.1 - 0.03 14.4 0.2 0.069 13.3 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) IncA PF04156.9 EKX72129.1 - 0.03 13.9 0.2 0.03 13.9 0.1 1.4 2 0 0 2 2 1 0 IncA protein bZIP_1 PF00170.16 EKX72129.1 - 0.037 13.9 1.7 0.088 12.7 1.2 1.6 1 0 0 1 1 1 0 bZIP transcription factor DUF4047 PF13256.1 EKX72129.1 - 0.044 13.7 0.1 0.088 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) TPR_MLP1_2 PF07926.7 EKX72129.1 - 0.044 13.5 0.5 0.044 13.5 0.3 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3573 PF12097.3 EKX72129.1 - 0.051 12.1 0.1 0.07 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DNA_RNApol_7kD PF03604.8 EKX72129.1 - 0.061 12.7 0.7 0.061 12.7 0.5 4.6 3 1 1 4 4 2 0 DNA directed RNA polymerase, 7 kDa subunit Myosin_tail_1 PF01576.14 EKX72129.1 - 0.064 10.9 0.5 0.086 10.5 0.4 1.1 1 0 0 1 1 1 0 Myosin tail DUF2443 PF10398.4 EKX72129.1 - 0.075 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) DUF2730 PF10805.3 EKX72129.1 - 0.089 12.5 0.3 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) FlxA PF14282.1 EKX72129.1 - 0.11 12.4 2.7 0.21 11.5 1.9 1.5 1 0 0 1 1 1 0 FlxA-like protein NPV_P10 PF05531.7 EKX72129.1 - 0.11 12.7 0.4 0.17 12.1 0.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.1 EKX72129.1 - 0.14 11.0 0.1 0.2 10.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atrophin-1 PF03154.10 EKX72129.1 - 0.18 9.9 0.4 0.25 9.4 0.3 1.2 1 0 0 1 1 1 0 Atrophin-1 family FAINT PF04385.10 EKX72130.1 - 4.5e-08 32.8 1.3 0.00061 19.5 0.0 2.6 3 0 0 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72131.1 - 2.7e-20 71.9 0.2 0.00023 20.9 0.0 4.3 4 0 0 4 4 4 4 Domain of unknown function, DUF529 EMA PF02488.10 EKX72131.1 - 0.0023 17.4 2.1 0.04 13.3 0.0 2.7 3 0 0 3 3 3 1 Merozoite Antigen Inh PF02974.9 EKX72131.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Protease inhibitor Inh FAINT PF04385.10 EKX72132.1 - 0.0012 18.6 3.2 0.0019 18.0 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function, DUF529 SH3_5 PF08460.5 EKX72132.1 - 0.016 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain FAINT PF04385.10 EKX72133.1 - 2.6e-08 33.5 1.7 0.0038 17.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF2871 PF11070.3 EKX72134.1 - 0.037 14.1 0.2 12 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) FAINT PF04385.10 EKX72135.1 - 0.00025 20.8 0.0 0.00087 19.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function, DUF529 EMA PF02488.10 EKX72135.1 - 0.019 14.4 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Merozoite Antigen DUF4196 PF13846.1 EKX72135.1 - 0.019 15.2 0.1 0.037 14.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) Guanylate_kin PF00625.16 EKX72137.1 - 0.012 15.0 0.3 0.017 14.5 0.2 1.2 1 0 0 1 1 1 0 Guanylate kinase FAINT PF04385.10 EKX72139.1 - 3.6e-14 52.3 0.6 2.6e-07 30.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function, DUF529 CDC50 PF03381.10 EKX72141.1 - 5.4e-22 78.2 2.1 7.6e-22 77.7 1.4 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ABC_tran PF00005.22 EKX72142.1 - 4e-31 108.1 0.0 1.7e-17 63.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 EKX72142.1 - 1.9e-05 24.7 0.1 0.028 14.4 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.1 EKX72142.1 - 7.8e-05 22.3 0.2 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EKX72142.1 - 0.00013 21.4 0.9 0.16 11.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EKX72142.1 - 0.00016 22.0 0.1 0.42 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EKX72142.1 - 0.00019 21.8 1.8 0.46 10.7 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EKX72142.1 - 0.00079 20.2 0.1 0.46 11.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.1 EKX72142.1 - 0.00099 19.1 9.6 0.088 12.7 0.1 3.8 5 0 0 5 5 3 2 AAA domain ArgK PF03308.11 EKX72142.1 - 0.001 17.9 1.1 0.0016 17.2 0.1 1.7 2 0 0 2 2 2 1 ArgK protein AAA_25 PF13481.1 EKX72142.1 - 0.0011 18.4 0.0 0.089 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EKX72142.1 - 0.0016 17.3 0.1 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 EKX72142.1 - 0.0022 17.2 0.3 0.17 11.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EKX72142.1 - 0.003 17.0 0.2 1 8.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 EKX72142.1 - 0.0051 16.6 2.2 0.13 12.0 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EKX72142.1 - 0.0074 15.4 0.2 2.9 6.9 0.1 2.5 2 0 0 2 2 2 1 Zeta toxin UPF0079 PF02367.12 EKX72142.1 - 0.0095 15.5 0.6 0.2 11.2 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 EKX72142.1 - 0.015 14.5 0.6 0.3 10.2 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 EKX72142.1 - 0.018 14.7 1.3 3.1 7.5 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain SbcCD_C PF13558.1 EKX72142.1 - 0.02 14.8 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EKX72142.1 - 0.021 14.5 0.3 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EKX72142.1 - 0.024 14.4 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Miro PF08477.8 EKX72142.1 - 0.025 15.0 0.0 15 6.1 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein DnaB_C PF03796.10 EKX72142.1 - 0.03 13.2 0.0 1 8.2 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_22 PF13401.1 EKX72142.1 - 0.035 14.2 0.1 13 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EKX72142.1 - 0.039 13.4 0.1 9 5.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 EKX72142.1 - 0.042 13.5 0.5 2.5 7.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.4 EKX72142.1 - 0.061 11.9 0.3 7.9 4.9 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF2791 PF10923.3 EKX72142.1 - 0.15 10.5 0.0 0.92 8.0 0.0 2.0 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) cobW PF02492.14 EKX72142.1 - 0.21 11.0 1.4 15 4.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FAINT PF04385.10 EKX72144.1 - 1.6e-12 47.0 0.1 4.3e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72144.1 - 0.042 13.3 0.0 0.12 11.8 0.0 1.6 1 1 1 2 2 2 0 Merozoite Antigen FAINT PF04385.10 EKX72145.1 - 0.00061 19.5 1.0 0.0013 18.5 0.4 1.7 1 1 0 1 1 1 1 Domain of unknown function, DUF529 EMA PF02488.10 EKX72145.1 - 0.0029 17.1 1.2 0.0042 16.6 0.8 1.2 1 0 0 1 1 1 1 Merozoite Antigen FAM163 PF15069.1 EKX72145.1 - 0.51 10.9 2.7 0.66 10.5 0.1 2.3 1 1 0 2 2 2 0 FAM163 family DUF2486 PF10667.4 EKX72145.1 - 3.7 8.0 20.7 6 7.3 14.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Peptidase_C1 PF00112.18 EKX72146.1 - 2.3e-20 73.4 0.0 5.3e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKX72146.1 - 0.0027 17.9 0.5 0.0055 16.9 0.3 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) PLDc_N PF13396.1 EKX72146.1 - 0.018 14.6 0.3 0.043 13.4 0.2 1.6 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal Cadherin_pro PF08758.6 EKX72148.1 - 0.045 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Cadherin prodomain like FAINT PF04385.10 EKX72149.1 - 1.4e-17 63.2 16.4 5.7e-09 35.6 1.3 4.2 4 0 0 4 4 4 3 Domain of unknown function, DUF529 EMA PF02488.10 EKX72149.1 - 0.00091 18.7 4.1 0.043 13.2 0.6 3.0 2 1 1 3 3 3 2 Merozoite Antigen FAINT PF04385.10 EKX72150.1 - 6.7e-19 67.5 2.1 1e-05 25.2 0.0 4.4 4 0 0 4 4 4 4 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72151.1 - 1.8e-17 62.9 0.0 0.00037 20.2 0.0 6.0 6 0 0 6 6 6 5 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72152.1 - 2.5e-08 33.6 0.0 0.062 13.1 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function, DUF529 HCBP_related PF06594.6 EKX72152.1 - 0.013 15.0 0.1 0.026 14.1 0.1 1.5 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain DHO_dh PF01180.16 EKX72152.1 - 0.14 11.1 0.1 4 6.2 0.0 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase GDPD PF03009.12 EKX72154.1 - 8.6e-12 45.0 0.0 5.9e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Usg PF06233.7 EKX72154.1 - 0.053 13.3 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Usg-like family Mitofilin PF09731.4 EKX72156.1 - 0.051 12.2 22.2 0.066 11.8 15.4 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HSBP1 PF06825.7 EKX72156.1 - 0.069 12.7 0.3 0.15 11.6 0.2 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 AAA_13 PF13166.1 EKX72156.1 - 7.9 4.8 18.4 2.9 6.2 11.3 1.4 1 1 0 1 1 1 0 AAA domain DUF572 PF04502.8 EKX72158.1 - 8.3e-55 186.2 8.1 1.1e-54 185.8 5.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) TF_Zn_Ribbon PF08271.7 EKX72158.1 - 4.5 6.6 6.1 0.27 10.5 0.3 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding FAINT PF04385.10 EKX72159.1 - 5.2e-23 80.6 1.8 8.8e-06 25.4 0.0 4.3 4 0 0 4 4 4 4 Domain of unknown function, DUF529 PAPS_reduct PF01507.14 EKX72160.1 - 1e-14 54.7 0.0 1.2e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family FAINT PF04385.10 EKX72161.1 - 2.1e-15 56.2 7.2 9.1e-10 38.2 0.1 3.8 3 2 0 3 3 3 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72161.1 - 6.1e-10 39.0 11.7 0.00027 20.5 0.5 3.2 2 1 1 3 3 3 3 Merozoite Antigen Thioredoxin_8 PF13905.1 EKX72161.1 - 0.12 12.4 0.5 39 4.4 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin-like FAINT PF04385.10 EKX72162.1 - 4.9e-09 35.9 0.4 9.2e-09 35.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function, DUF529 PAPS_reduct PF01507.14 EKX72162.1 - 2.8e-06 27.2 0.0 4.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family OrfB_Zn_ribbon PF07282.6 EKX72164.1 - 0.24 11.0 1.9 0.59 9.8 1.3 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain RRM_1 PF00076.17 EKX72165.1 - 9.8e-17 60.3 0.6 1.3e-16 60.0 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX72165.1 - 3.6e-13 49.2 0.0 6.4e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX72165.1 - 5.2e-08 32.6 0.0 8.7e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKX72165.1 - 0.088 12.5 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FAINT PF04385.10 EKX72168.1 - 0.011 15.5 1.4 0.21 11.4 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function, DUF529 Amidohydro_4 PF13147.1 EKX72168.1 - 0.18 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase FAINT PF04385.10 EKX72170.1 - 1.7e-11 43.7 2.0 2.9e-07 30.2 0.1 2.7 3 0 0 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72172.1 - 5.6e-10 38.9 0.6 2.2e-05 24.2 0.3 3.0 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72173.1 - 8.8e-24 83.1 2.0 5.2e-07 29.4 0.0 4.8 4 1 0 4 4 4 4 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72175.1 - 9.1e-13 47.8 7.4 0.00013 21.7 0.2 3.9 4 0 0 4 4 4 3 Domain of unknown function, DUF529 Thioredoxin_8 PF13905.1 EKX72175.1 - 2.9e-05 24.0 0.0 0.027 14.5 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like DUF237 PF03072.9 EKX72175.1 - 0.033 14.0 0.0 0.83 9.5 0.0 2.7 2 0 0 2 2 2 0 MG032/MG096/MG288 family 1 FAINT PF04385.10 EKX72176.1 - 4.8e-07 29.5 0.0 6.4e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72178.1 - 0.029 14.2 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, DUF529 EMA PF02488.10 EKX72178.1 - 0.054 12.9 0.0 0.064 12.7 0.0 1.1 1 0 0 1 1 1 0 Merozoite Antigen Raffinose_syn PF05691.7 EKX72178.1 - 0.1 10.1 0.0 0.11 9.9 0.0 1.0 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 FAINT PF04385.10 EKX72179.1 - 4e-09 36.1 0.0 0.00047 19.9 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72179.1 - 0.0016 18.0 0.4 11 5.4 0.0 3.6 2 1 2 4 4 4 3 Merozoite Antigen DUF3899 PF13038.1 EKX72179.1 - 0.042 13.9 0.1 0.15 12.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) RVT_1 PF00078.22 EKX72182.1 - 9.3e-30 103.5 0.1 1.4e-29 103.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAINT PF04385.10 EKX72183.1 - 2.2e-11 43.4 5.6 0.0027 17.5 0.1 4.6 3 1 1 4 4 4 3 Domain of unknown function, DUF529 Phenol_MetA_deg PF13557.1 EKX72186.1 - 0.11 12.3 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Putative MetA-pathway of phenol degradation FAINT PF04385.10 EKX72187.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Scytalone_dh PF02982.9 EKX72187.1 - 0.025 14.1 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase BPL_LplA_LipB PF03099.14 EKX72188.1 - 0.0014 18.6 0.0 0.051 13.6 0.0 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Flavodoxin_1 PF00258.20 EKX72190.1 - 7.6e-23 81.0 0.3 1.8e-22 79.8 0.2 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EKX72190.1 - 1.8e-14 54.2 0.0 5.4e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.15 EKX72190.1 - 2.5e-12 46.7 0.0 9.3e-12 44.8 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain FAINT PF04385.10 EKX72192.1 - 2.8e-05 23.8 2.5 0.023 14.5 0.0 3.2 4 0 0 4 4 4 2 Domain of unknown function, DUF529 RRP14 PF15459.1 EKX72192.1 - 0.052 13.6 1.4 0.41 10.7 0.0 2.6 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 AP2 PF00847.15 EKX72196.1 - 7e-08 32.5 0.5 1.6e-07 31.3 0.4 1.6 1 0 0 1 1 1 1 AP2 domain Filamin PF00630.14 EKX72197.1 - 2.4e-10 40.8 0.0 1.1e-05 25.9 0.0 2.6 2 0 0 2 2 2 2 Filamin/ABP280 repeat GST_C_3 PF14497.1 EKX72197.1 - 0.035 14.5 0.3 3.9 7.9 0.0 2.5 1 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SPX PF03105.14 EKX72197.1 - 0.66 9.7 4.6 0.97 9.1 3.2 1.3 1 0 0 1 1 1 0 SPX domain DUF2408 PF10303.4 EKX72197.1 - 1.8 8.6 6.8 7.1 6.7 4.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Syntaxin-6_N PF09177.6 EKX72197.1 - 8.9 6.7 7.5 8.4 6.8 2.0 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CRAL_TRIO_2 PF13716.1 EKX72198.1 - 1.1e-15 57.8 2.7 1.2e-15 57.7 0.8 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EKX72198.1 - 6.1e-07 29.1 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FAINT PF04385.10 EKX72200.1 - 8.8e-08 31.8 1.3 1.5e-07 31.1 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Arfaptin PF06456.8 EKX72200.1 - 0.00087 18.6 0.4 0.0014 18.0 0.3 1.2 1 0 0 1 1 1 1 Arfaptin-like domain HMG_box_5 PF14887.1 EKX72200.1 - 0.015 15.0 1.0 1.3 8.8 0.1 3.1 2 1 1 3 3 3 0 HMG (high mobility group) box 5 EMA PF02488.10 EKX72200.1 - 0.016 14.7 0.8 0.016 14.7 0.5 1.5 2 0 0 2 2 2 0 Merozoite Antigen COG2 PF06148.6 EKX72200.1 - 0.069 13.0 0.5 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TarH PF02203.10 EKX72200.1 - 0.094 12.5 1.1 0.24 11.2 0.2 1.8 2 0 0 2 2 2 0 Tar ligand binding domain homologue MSP1_C PF07462.6 EKX72200.1 - 2.6 6.3 10.6 0.21 9.9 0.3 2.8 3 0 0 3 3 3 0 Merozoite surface protein 1 (MSP1) C-terminus FAINT PF04385.10 EKX72201.1 - 5.3e-20 71.0 0.2 1.7e-05 24.5 0.0 3.8 3 1 0 3 3 3 3 Domain of unknown function, DUF529 Peptidase_C1 PF00112.18 EKX72203.1 - 1.2e-48 165.8 0.4 1.9e-48 165.2 0.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EKX72203.1 - 2.5e-06 26.3 0.3 4.3e-06 25.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase C1-like family FAINT PF04385.10 EKX72204.1 - 0.00031 20.5 2.7 0.00031 20.5 1.9 3.9 3 1 1 4 4 4 1 Domain of unknown function, DUF529 Saf-Nte_pilin PF09460.5 EKX72204.1 - 0.0098 15.6 0.2 0.9 9.3 0.1 2.3 2 0 0 2 2 2 2 Saf-pilin pilus formation protein FAINT PF04385.10 EKX72205.1 - 3.7e-05 23.4 0.8 0.35 10.7 0.1 3.2 3 1 0 3 3 3 2 Domain of unknown function, DUF529 ABC_tran PF00005.22 EKX72206.1 - 4.3e-34 117.7 0.0 2e-17 63.8 0.0 3.5 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EKX72206.1 - 2.4e-07 31.0 6.5 0.014 15.3 0.2 5.2 6 0 0 6 6 5 2 AAA domain AAA_16 PF13191.1 EKX72206.1 - 1.1e-06 28.8 0.6 0.006 16.5 0.0 2.9 4 0 0 4 4 2 2 AAA ATPase domain AAA_18 PF13238.1 EKX72206.1 - 3.3e-05 24.1 0.8 0.23 11.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EKX72206.1 - 3.8e-05 24.4 0.1 0.15 12.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EKX72206.1 - 6.8e-05 22.3 5.2 0.092 12.2 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain ArgK PF03308.11 EKX72206.1 - 7.1e-05 21.7 0.4 0.0014 17.4 0.1 2.1 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EKX72206.1 - 0.00013 22.4 0.7 3.6 8.1 0.0 3.8 4 0 0 4 4 3 1 Miro-like protein DUF258 PF03193.11 EKX72206.1 - 0.00013 21.1 1.2 0.12 11.5 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EKX72206.1 - 0.00019 20.8 0.0 0.032 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EKX72206.1 - 0.00035 20.4 1.8 0.06 13.1 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_30 PF13604.1 EKX72206.1 - 0.00048 19.7 1.6 0.067 12.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EKX72206.1 - 0.00056 18.9 1.1 0.29 9.9 0.1 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_23 PF13476.1 EKX72206.1 - 0.00082 19.7 10.2 0.0079 16.5 0.4 3.0 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.18 EKX72206.1 - 0.0014 18.5 2.5 0.53 10.0 0.0 3.5 3 0 0 3 3 3 1 Dynamin family FtsK_SpoIIIE PF01580.13 EKX72206.1 - 0.0016 17.9 0.6 0.27 10.6 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family SMC_N PF02463.14 EKX72206.1 - 0.0018 17.5 0.7 0.026 13.7 0.1 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EKX72206.1 - 0.003 17.5 1.2 0.31 10.9 0.0 3.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EKX72206.1 - 0.0038 16.3 0.2 2.8 7.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Fer4_NifH PF00142.13 EKX72206.1 - 0.0054 15.9 0.1 2.2 7.3 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.1 EKX72206.1 - 0.0062 16.6 0.9 2.3 8.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 EKX72206.1 - 0.0072 16.0 1.5 0.75 9.4 0.0 3.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 EKX72206.1 - 0.011 14.7 0.3 0.26 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 EKX72206.1 - 0.032 13.9 3.5 6.2 6.6 0.1 3.6 4 0 0 4 4 4 0 Part of AAA domain DUF2791 PF10923.3 EKX72206.1 - 0.033 12.8 0.1 0.25 9.9 0.0 2.2 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) Arch_ATPase PF01637.13 EKX72206.1 - 0.035 13.7 0.7 6.7 6.3 0.0 3.1 4 0 0 4 4 2 0 Archaeal ATPase AAA_10 PF12846.2 EKX72206.1 - 0.039 13.3 1.7 7.1 5.9 0.1 2.6 3 0 0 3 3 2 0 AAA-like domain AAA_14 PF13173.1 EKX72206.1 - 0.061 13.2 0.1 12 5.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EKX72206.1 - 0.063 12.9 2.7 6.1 6.4 0.0 2.8 3 0 0 3 3 2 0 NACHT domain RNA_helicase PF00910.17 EKX72206.1 - 0.07 13.3 0.0 9.3 6.4 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 EKX72206.1 - 0.072 12.9 0.7 5.5 6.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain UPF0079 PF02367.12 EKX72206.1 - 0.12 11.9 1.9 3 7.4 0.1 2.9 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 EKX72206.1 - 0.13 10.8 0.1 5.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SbcCD_C PF13558.1 EKX72206.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EKX72206.1 - 1.3 8.9 3.9 53 3.7 0.1 3.4 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EKX72206.1 - 1.5 8.2 4.7 7.4 5.9 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain FAINT PF04385.10 EKX72207.1 - 3.7e-11 42.7 1.4 6.4e-06 25.9 0.4 2.7 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72209.1 - 4.9e-06 26.2 0.0 9.8e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function, DUF529 zf-RING_2 PF13639.1 EKX72211.1 - 9.5e-10 38.1 1.7 9.5e-10 38.1 1.2 2.9 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EKX72211.1 - 4.8e-06 26.5 1.8 1.2e-05 25.3 1.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EKX72211.1 - 5.3e-06 26.3 1.6 5.3e-06 26.3 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKX72211.1 - 1.3e-05 24.7 2.1 4.5e-05 23.0 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKX72211.1 - 6e-05 22.6 0.6 6e-05 22.6 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKX72211.1 - 0.0012 18.4 2.8 0.0025 17.4 0.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EKX72211.1 - 0.011 15.5 0.2 0.022 14.5 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EKX72211.1 - 0.015 14.9 0.7 0.045 13.4 0.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger UPF0547 PF10571.4 EKX72211.1 - 0.057 13.1 0.3 8 6.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-FCS PF06467.9 EKX72211.1 - 0.12 12.0 2.3 2.9 7.6 0.2 2.7 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF2053 PF09767.4 EKX72212.1 - 1e-14 54.8 8.0 1.6e-14 54.1 5.5 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) SPW PF03779.9 EKX72212.1 - 0.42 10.0 2.4 1.1 8.7 1.7 1.7 1 0 0 1 1 1 0 SPW repeat DUF4231 PF14015.1 EKX72212.1 - 0.59 10.1 3.4 0.47 10.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DJ-1_PfpI PF01965.19 EKX72213.1 - 4.5e-21 74.8 0.1 6.1e-21 74.4 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EKX72213.1 - 4.3e-10 39.1 0.0 6.7e-10 38.4 0.0 1.3 1 1 0 1 1 1 1 Putative amidotransferase FAINT PF04385.10 EKX72215.1 - 8.3e-80 262.6 40.7 2.8e-09 36.6 0.2 13.6 13 0 0 13 13 13 13 Domain of unknown function, DUF529 Tox-SHH PF15652.1 EKX72215.1 - 0.71 10.4 6.8 72 4.0 0.0 5.0 5 0 0 5 5 5 0 HNH/Endo VII superfamily toxin with a SHH signature Peptidase_C1 PF00112.18 EKX72216.1 - 6.2e-28 98.1 0.0 1e-27 97.4 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Ribosomal_S13 PF00416.17 EKX72219.1 - 0.0046 17.3 0.3 0.011 16.1 0.0 1.7 1 1 1 2 2 2 1 Ribosomal protein S13/S18 DUF536 PF04394.9 EKX72219.1 - 0.11 12.2 2.4 0.13 11.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF536 FAINT PF04385.10 EKX72220.1 - 2.1e-14 53.1 0.2 4.5e-06 26.4 0.0 3.7 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 EKX72220.1 - 4e-07 29.7 5.8 0.0033 16.9 0.3 2.3 2 0 0 2 2 2 2 Merozoite Antigen Thiol-ester_cl PF10569.4 EKX72220.1 - 0.048 12.8 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 Alpha-macro-globulin thiol-ester bond-forming region YPEB PF14620.1 EKX72220.1 - 0.07 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 YpeB sporulation Ribosomal_L18p PF00861.17 EKX72222.1 - 3.9e-09 36.7 0.1 2.4e-08 34.2 0.1 2.0 1 1 0 1 1 1 1 Ribosomal L18p/L5e family FAINT PF04385.10 EKX72222.1 - 8.6e-09 35.1 0.0 0.0034 17.1 0.0 3.8 3 0 0 3 3 3 3 Domain of unknown function, DUF529 DNA_ligase_A_C PF04679.10 EKX72222.1 - 0.057 13.8 0.1 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region Nop14 PF04147.7 EKX72223.1 - 0.65 7.8 6.3 0.94 7.3 4.4 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L2 PF00181.18 EKX72226.1 - 0.022 14.7 0.4 0.041 13.8 0.3 1.4 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain FAINT PF04385.10 EKX72227.1 - 8.5e-09 35.1 0.1 0.0032 17.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF2745 PF10922.3 EKX72227.1 - 0.017 15.0 0.0 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2745) Sec1 PF00995.18 EKX72228.1 - 1.3e-88 298.0 4.1 1.9e-88 297.5 2.8 1.2 1 0 0 1 1 1 1 Sec1 family DUF1347 PF07079.6 EKX72230.1 - 0.019 13.2 0.1 0.024 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) Urm1 PF09138.6 EKX72231.1 - 0.014 15.5 0.2 0.039 14.0 0.1 1.7 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) FAINT PF04385.10 EKX72232.1 - 5.9e-94 308.0 115.7 1.7e-06 27.7 2.7 27.0 26 0 0 26 26 26 25 Domain of unknown function, DUF529 TruB-C_2 PF09157.6 EKX72232.1 - 0.74 9.7 0.0 1.7 8.5 0.0 1.5 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal FAINT PF04385.10 EKX72233.1 - 8.2e-06 25.5 0.2 1.2e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 EMA PF02488.10 EKX72233.1 - 0.036 13.5 0.3 0.045 13.2 0.2 1.2 1 0 0 1 1 1 0 Merozoite Antigen FAINT PF04385.10 EKX72234.1 - 1.2e-14 53.8 0.8 4.5e-06 26.4 0.0 3.0 2 1 1 3 3 3 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72234.1 - 4.7e-05 22.9 3.6 0.0029 17.1 0.3 2.1 1 1 0 2 2 2 2 Merozoite Antigen Saf-Nte_pilin PF09460.5 EKX72234.1 - 0.013 15.2 0.3 5.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Saf-pilin pilus formation protein FAINT PF04385.10 EKX72235.1 - 0.00043 20.0 1.7 0.00084 19.1 0.8 1.9 1 1 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72236.1 - 7.2e-09 35.3 5.2 1.1e-05 25.2 0.2 2.7 3 0 0 3 3 3 2 Domain of unknown function, DUF529 FAD_binding_9 PF08021.6 EKX72236.1 - 0.0043 17.0 0.0 4.2 7.3 0.0 2.6 2 1 0 2 2 2 2 Siderophore-interacting FAD-binding domain PilJ PF13675.1 EKX72237.1 - 0.017 15.4 4.0 1.8 8.9 0.0 3.9 2 2 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term WXG100 PF06013.7 EKX72237.1 - 0.13 12.3 6.1 42 4.2 0.0 5.2 5 1 0 5 5 5 0 Proteins of 100 residues with WXG Plasmid_stabil PF05016.9 EKX72237.1 - 0.77 10.1 3.5 3 8.3 0.2 3.1 3 0 0 3 3 3 0 Plasmid stabilisation system protein Syntaxin-6_N PF09177.6 EKX72237.1 - 5.7 7.4 25.0 1.2 9.5 0.9 4.4 2 2 2 4 4 4 0 Syntaxin 6, N-terminal DUF2203 PF09969.4 EKX72237.1 - 6.5 7.0 21.0 12 6.1 0.2 4.4 3 2 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) FAINT PF04385.10 EKX72238.1 - 0.0067 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72239.1 - 9.1e-12 44.6 4.7 6.6e-07 29.0 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 LMF1 PF06762.9 EKX72240.1 - 7.3e-55 186.3 4.0 2.6e-54 184.5 2.8 1.9 1 1 0 1 1 1 1 Lipase maturation factor FAINT PF04385.10 EKX72241.1 - 0.011 15.5 0.2 0.021 14.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Pyr_redox_2 PF07992.9 EKX72242.1 - 1.9e-32 112.8 0.4 2.6e-32 112.3 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EKX72242.1 - 4.8e-27 94.1 0.0 1.3e-26 92.7 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EKX72242.1 - 5.4e-15 55.5 2.7 4.4e-12 46.2 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKX72242.1 - 1.9e-10 41.1 0.0 4.2e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKX72242.1 - 6.6e-07 28.5 0.0 1.2e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 EKX72242.1 - 3.5e-06 26.1 3.0 6.9e-06 25.1 0.5 2.3 2 1 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EKX72242.1 - 0.00011 21.4 0.5 0.00017 20.7 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EKX72242.1 - 0.00013 20.6 0.7 0.0003 19.3 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EKX72242.1 - 0.00091 18.1 0.3 0.0014 17.5 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EKX72242.1 - 0.00094 19.1 4.5 0.001 19.0 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EKX72242.1 - 0.0018 17.4 0.3 0.0029 16.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EKX72242.1 - 0.0018 17.2 0.2 0.0018 17.2 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EKX72242.1 - 0.01 15.3 1.5 1.8 8.1 0.1 2.9 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EKX72242.1 - 0.058 13.6 0.2 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EKX72242.1 - 0.078 12.0 0.6 0.14 11.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Cnd2 PF05786.9 EKX72244.1 - 2.7e-32 112.1 13.4 5.7e-21 74.7 3.4 3.4 3 1 0 3 3 3 2 Condensin complex subunit 2 FAINT PF04385.10 EKX72245.1 - 4.2e-20 71.3 9.2 4.9e-05 23.1 0.0 4.9 5 0 0 5 5 5 4 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72246.1 - 6.9e-32 109.1 1.8 3.1e-05 23.7 0.0 6.5 6 0 0 6 6 6 5 Domain of unknown function, DUF529 EMA PF02488.10 EKX72246.1 - 0.00073 19.0 3.8 0.28 10.6 0.0 3.5 4 0 0 4 4 4 3 Merozoite Antigen FAINT PF04385.10 EKX72249.1 - 1.1e-10 41.1 2.2 6e-08 32.4 0.2 2.8 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72250.1 - 1.5e-11 43.9 9.1 7.3e-07 28.9 0.3 4.2 3 2 1 4 4 4 3 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72251.1 - 1.2e-46 156.4 31.3 2.6e-11 43.2 0.2 9.9 9 0 0 9 9 9 9 Domain of unknown function, DUF529 ThiC PF01964.13 EKX72251.1 - 0.084 11.3 0.0 0.42 9.0 0.0 1.9 2 0 0 2 2 2 0 ThiC family SDA1 PF05285.7 EKX72252.1 - 1.9e-14 53.6 66.8 5.2e-08 32.5 27.0 3.3 2 1 0 3 3 3 2 SDA1 DUF2457 PF10446.4 EKX72252.1 - 0.0012 17.7 27.8 0.0022 16.8 19.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CENP-T PF15511.1 EKX72252.1 - 0.014 14.6 15.6 0.022 14.0 10.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T IBP39 PF11422.3 EKX72252.1 - 0.028 13.9 1.2 0.054 12.9 0.1 1.9 2 0 0 2 2 2 0 Initiator binding protein 39 kDa Daxx PF03344.10 EKX72252.1 - 0.051 12.0 25.1 0.07 11.6 17.4 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EKX72252.1 - 0.63 7.9 33.7 0.11 10.4 20.9 1.5 2 0 0 2 2 2 0 Nop14-like family Collagen PF01391.13 EKX72253.1 - 0.049 13.1 13.8 0.16 11.5 9.6 1.8 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Tbf5 PF06331.7 EKX72255.1 - 1.7e-06 27.6 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Arf PF00025.16 EKX72256.1 - 2.7e-41 140.6 0.1 5e-41 139.8 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EKX72256.1 - 9.3e-06 24.5 0.0 2.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.5 EKX72256.1 - 0.0025 17.0 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EKX72256.1 - 0.014 14.8 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 Ras family Gtr1_RagA PF04670.7 EKX72256.1 - 0.015 14.4 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Arf PF00025.16 EKX72257.1 - 7.1e-19 67.7 0.3 7.5e-19 67.6 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EKX72257.1 - 0.00046 18.9 0.1 0.00051 18.8 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EKX72257.1 - 0.00069 19.5 0.1 0.00083 19.2 0.1 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKX72257.1 - 0.0026 17.0 0.0 0.0028 16.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EKX72257.1 - 0.008 15.9 0.2 0.0081 15.8 0.1 1.0 1 0 0 1 1 1 1 Archaeal ATPase PduV-EutP PF10662.4 EKX72257.1 - 0.022 14.2 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EKX72257.1 - 0.027 14.9 0.0 0.03 14.8 0.0 1.1 1 0 0 1 1 1 0 Miro-like protein AAA_15 PF13175.1 EKX72257.1 - 0.066 12.2 0.2 0.066 12.2 0.2 1.1 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 EKX72257.1 - 0.083 12.0 0.0 0.093 11.8 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 EKX72257.1 - 0.089 13.0 0.0 0.089 13.0 0.0 1.1 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EKX72257.1 - 0.09 12.6 0.0 0.093 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 EKX72257.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Ras family AAA_18 PF13238.1 EKX72257.1 - 0.12 12.7 0.1 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain FAINT PF04385.10 EKX72258.1 - 5.8e-06 26.0 0.0 9.8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Zona_pellucida PF00100.18 EKX72260.1 - 0.0058 16.1 0.3 0.0079 15.6 0.2 1.3 1 1 0 1 1 1 1 Zona pellucida-like domain FAINT PF04385.10 EKX72260.1 - 0.062 13.1 0.1 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Ribosomal_L13e PF01294.13 EKX72260.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L13e FAINT PF04385.10 EKX72261.1 - 2.2e-20 72.2 0.5 0.032 14.0 0.0 5.9 5 0 0 5 5 5 5 Domain of unknown function, DUF529 Collagen PF01391.13 EKX72262.1 - 0.14 11.7 9.9 0.18 11.3 6.9 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) AAA_31 PF13614.1 EKX72263.1 - 0.01 15.7 0.1 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain HEAT PF02985.17 EKX72265.1 - 0.0028 17.5 0.0 0.011 15.7 0.0 2.0 1 0 0 1 1 1 1 HEAT repeat HEAT_2 PF13646.1 EKX72265.1 - 0.06 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats IFRD PF05004.8 EKX72265.1 - 0.081 11.9 1.0 1.1 8.2 0.1 2.2 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 EKX72267.1 - 3.9e-05 23.8 0.0 0.0011 19.2 0.0 2.7 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EKX72267.1 - 0.026 14.5 0.0 1.7 8.9 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat EMA PF02488.10 EKX72270.1 - 1.3e-13 51.0 0.6 1.9e-13 50.5 0.4 1.2 1 0 0 1 1 1 1 Merozoite Antigen RVT_1 PF00078.22 EKX72272.1 - 1e-20 74.0 0.0 1.2e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAINT PF04385.10 EKX72274.1 - 1.1e-07 31.5 0.2 0.0056 16.5 0.5 2.6 2 1 0 2 2 2 2 Domain of unknown function, DUF529 Laminin_II PF06009.7 EKX72275.1 - 0.05 13.3 2.4 1.7 8.3 0.4 2.1 1 1 1 2 2 2 0 Laminin Domain II TarH PF02203.10 EKX72275.1 - 0.11 12.3 1.5 1.9 8.2 0.8 2.1 1 1 1 2 2 2 0 Tar ligand binding domain homologue TBCA PF02970.11 EKX72275.1 - 0.27 11.3 3.4 0.42 10.7 0.7 2.2 1 1 0 2 2 2 0 Tubulin binding cofactor A COG2 PF06148.6 EKX72275.1 - 0.31 10.9 2.4 0.49 10.2 0.4 1.9 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PTS_IIA PF02255.11 EKX72275.1 - 0.33 10.8 2.4 2.6 7.9 0.3 2.3 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF4398 PF14346.1 EKX72275.1 - 0.34 11.0 6.1 0.34 10.9 0.6 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4398) Stm1_N PF09598.5 EKX72275.1 - 1.6 9.4 7.7 3.8 8.2 5.3 1.7 1 0 0 1 1 1 0 Stm1 DUF4131 PF13567.1 EKX72276.1 - 4.4 6.6 7.1 19 4.6 1.1 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4131) Cas_Csy4 PF09618.5 EKX72277.1 - 0.0059 16.4 0.9 0.01 15.6 0.7 1.3 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csy4) FAINT PF04385.10 EKX72279.1 - 2.3e-06 27.3 0.1 0.055 13.3 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72279.1 - 0.0033 16.9 0.1 0.0081 15.6 0.0 1.6 1 1 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 EKX72281.1 - 1.7e-05 24.5 0.4 5.3e-05 22.9 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function, DUF529 CBM_25 PF03423.8 EKX72281.1 - 0.092 12.8 0.0 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Serglycin PF04360.7 EKX72283.1 - 0.22 11.2 0.5 0.38 10.4 0.3 1.3 1 0 0 1 1 1 0 Serglycin FAINT PF04385.10 EKX72284.1 - 3.8e-05 23.4 0.0 8.3e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function, DUF529 DUF4428 PF14471.1 EKX72285.1 - 0.002 17.8 0.1 0.0079 15.9 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) SUKH_5 PF14567.1 EKX72285.1 - 0.17 11.2 1.4 2.1 7.8 0.0 2.8 3 0 0 3 3 3 0 SMI1-KNR4 cell-wall FAINT PF04385.10 EKX72286.1 - 1.5e-05 24.7 0.1 1.5e-05 24.7 0.1 2.2 2 1 1 3 3 3 1 Domain of unknown function, DUF529 GCR PF02155.10 EKX72286.1 - 0.027 13.1 0.5 0.027 13.1 0.3 1.6 2 0 0 2 2 2 0 Glucocorticoid receptor zf-HIT PF04438.11 EKX72287.1 - 1.7 8.3 12.6 0.24 11.0 6.3 1.5 2 0 0 2 2 2 0 HIT zinc finger zf-tcix PF14952.1 EKX72287.1 - 3.2 7.1 11.5 6.4 6.1 8.0 1.5 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Sugar_tr PF00083.19 EKX72291.1 - 3.6e-58 197.2 36.4 4.5e-58 196.9 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKX72291.1 - 9e-12 44.3 37.6 9.4e-08 31.1 11.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EKX72291.1 - 3.9e-05 22.0 2.2 3.9e-05 22.0 1.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) KH_1 PF00013.24 EKX72292.1 - 0.11 12.1 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 KH domain PPP4R2 PF09184.6 EKX72293.1 - 0.0037 16.8 9.3 0.0057 16.2 6.5 1.2 1 0 0 1 1 1 1 PPP4R2 DUF3295 PF11702.3 EKX72293.1 - 0.36 9.7 3.7 0.41 9.5 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) PRTP PF01366.13 EKX72293.1 - 4.3 5.1 5.4 8.4 4.2 1.5 2.0 2 0 0 2 2 2 0 Herpesvirus processing and transport protein Nop14 PF04147.7 EKX72293.1 - 4.5 5.0 16.3 5.6 4.7 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family RhoGEF PF00621.15 EKX72296.1 - 0.017 15.0 1.6 0.041 13.7 0.2 2.1 2 0 0 2 2 2 0 RhoGEF domain Prok_Ub PF14454.1 EKX72301.1 - 0.092 12.4 0.1 0.47 10.1 0.0 2.2 3 0 0 3 3 3 0 Prokaryotic Ubiquitin FAINT PF04385.10 EKX72303.1 - 1.4e-11 44.0 0.3 6.7e-07 29.0 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Syntaxin PF00804.20 EKX72304.1 - 0.0019 18.3 4.8 0.0021 18.1 0.7 2.6 3 0 0 3 3 3 1 Syntaxin Baculo_PEP_C PF04513.7 EKX72304.1 - 0.0051 16.6 5.5 0.11 12.2 1.1 3.1 3 1 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 EKX72304.1 - 0.03 14.1 0.1 0.094 12.5 0.0 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4547 PF15080.1 EKX72304.1 - 0.077 12.4 1.1 5.4 6.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4547) PspA_IM30 PF04012.7 EKX72304.1 - 0.91 8.8 9.5 0.35 10.1 4.0 2.1 2 0 0 2 2 2 0 PspA/IM30 family Cortex-I_coil PF09304.5 EKX72304.1 - 1 9.4 6.9 8 6.5 0.2 3.3 2 2 1 3 3 3 0 Cortexillin I, coiled coil Syntaxin-6_N PF09177.6 EKX72304.1 - 1.3 9.4 5.4 15 6.0 0.0 3.9 3 1 2 5 5 5 0 Syntaxin 6, N-terminal Spc7 PF08317.6 EKX72304.1 - 3.3 6.2 5.6 0.75 8.3 0.8 2.0 3 0 0 3 3 3 0 Spc7 kinetochore protein Transket_pyr PF02779.19 EKX72305.1 - 1.1e-50 171.5 0.0 2.3e-50 170.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EKX72305.1 - 1.5e-49 168.3 0.0 2.3e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF3538 PF12057.3 EKX72305.1 - 0.21 11.1 0.1 2.3 7.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3538) TFIIS_M PF07500.9 EKX72306.1 - 7.6e-16 58.2 0.5 7.6e-16 58.2 0.4 1.9 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain CDC45 PF02724.9 EKX72306.1 - 3 5.7 8.8 4.5 5.1 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2407_C PF13373.1 EKX72312.1 - 0.085 12.7 0.1 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 DUF2407 C-terminal domain TBP-binding PF09247.6 EKX72312.1 - 1.4 9.2 5.7 20 5.4 1.5 2.5 2 0 0 2 2 2 0 TATA box-binding protein binding Gram_pos_anchor PF00746.16 EKX72312.1 - 8.3 6.3 6.0 0.98 9.3 0.7 2.1 2 0 0 2 2 2 0 Gram positive anchor Neur_chan_memb PF02932.11 EKX72312.1 - 8.5 6.1 7.2 20 4.9 5.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAINT PF04385.10 EKX72313.1 - 7e-06 25.7 1.1 0.13 12.0 0.1 2.8 3 0 0 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72314.1 - 6e-06 26.0 0.3 0.00046 19.9 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 23S_rRNA_IVP PF05635.6 EKX72314.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein FAINT PF04385.10 EKX72316.1 - 1.4e-13 50.4 2.3 9.8e-06 25.3 0.0 3.9 4 0 0 4 4 4 3 Domain of unknown function, DUF529 SNF2_N PF00176.18 EKX72317.1 - 2.6e-63 213.6 0.2 1.2e-62 211.4 0.0 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKX72317.1 - 1.1e-17 63.6 0.1 8.9e-17 60.7 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.20 EKX72317.1 - 3.1e-11 43.0 0.1 1.8e-10 40.5 0.0 2.4 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.10 EKX72317.1 - 1.7e-08 34.5 0.0 2e-06 27.7 0.0 4.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit QLQ PF08880.6 EKX72317.1 - 0.0043 16.4 0.0 0.0087 15.4 0.0 1.5 1 0 0 1 1 1 1 QLQ FAINT PF04385.10 EKX72318.1 - 9.6e-07 28.5 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 CRAL_TRIO PF00650.15 EKX72319.1 - 6.5e-35 119.9 0.2 9.5e-35 119.4 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EKX72319.1 - 4.4e-09 36.4 0.1 6.6e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain EMA PF02488.10 EKX72320.1 - 0.00023 20.7 0.1 0.00028 20.4 0.1 1.2 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 EKX72320.1 - 0.0011 18.7 0.4 0.0027 17.5 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72321.1 - 0.00083 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Snf7 PF03357.16 EKX72322.1 - 9.5e-27 93.4 11.7 1.2e-26 93.1 8.1 1.1 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 EKX72322.1 - 0.0066 16.6 2.9 0.13 12.5 0.5 2.6 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein YPEB PF14620.1 EKX72322.1 - 0.24 10.3 8.5 5 6.0 0.0 2.0 1 1 1 2 2 2 0 YpeB sporulation Evr1_Alr PF04777.8 EKX72324.1 - 2e-10 40.4 0.2 2.5e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Erv1 / Alr family MMR_HSR1 PF01926.18 EKX72325.1 - 1.9e-14 53.6 0.0 4.1e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKX72325.1 - 0.00011 21.5 0.0 0.00028 20.2 0.0 1.8 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EKX72325.1 - 0.00038 19.9 0.0 0.0024 17.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EKX72325.1 - 0.049 13.4 0.0 5.4 6.7 0.0 2.4 1 1 1 2 2 2 0 Dynamin family DUF258 PF03193.11 EKX72325.1 - 0.06 12.5 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FAINT PF04385.10 EKX72327.1 - 3.8e-13 49.0 0.2 0.01 15.6 0.0 4.7 4 1 0 4 4 4 4 Domain of unknown function, DUF529 CBF_beta PF02312.12 EKX72327.1 - 0.013 15.1 0.0 0.25 10.9 0.0 2.2 2 0 0 2 2 2 0 Core binding factor beta subunit AAA_13 PF13166.1 EKX72328.1 - 0.0034 15.9 6.6 0.004 15.6 4.6 1.1 1 0 0 1 1 1 1 AAA domain ISN1 PF06437.6 EKX72328.1 - 0.09 11.4 1.8 0.13 10.9 1.2 1.2 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase P35 PF02331.10 EKX72328.1 - 0.096 11.7 2.4 0.15 11.1 1.5 1.3 1 1 0 1 1 1 0 Apoptosis preventing protein Vac_Fusion PF02346.11 EKX72328.1 - 0.11 11.8 1.8 0.35 10.3 1.3 1.8 1 0 0 1 1 1 0 Chordopoxvirus fusion protein DUF4613 PF15390.1 EKX72328.1 - 0.15 10.2 4.5 0.18 9.9 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Cytochrom_C_2 PF01322.15 EKX72328.1 - 0.17 12.3 4.9 0.28 11.7 3.4 1.3 1 0 0 1 1 1 0 Cytochrome C' PTRF_SDPR PF15237.1 EKX72328.1 - 0.23 10.8 10.2 0.41 10.0 7.1 1.4 1 0 0 1 1 1 0 PTRF/SDPR family DUF4407 PF14362.1 EKX72328.1 - 0.27 10.1 3.5 0.38 9.6 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Osmo_CC PF08946.5 EKX72328.1 - 0.69 9.9 9.0 2.1 8.4 6.2 1.9 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF848 PF05852.6 EKX72328.1 - 0.91 9.3 8.5 0.6 9.9 3.2 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1788 PF08747.6 EKX72328.1 - 1.8 8.4 4.9 5.9 6.7 2.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1788) DUF4446 PF14584.1 EKX72328.1 - 3.5 7.4 9.4 1.1 9.0 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF1700 PF08006.6 EKX72328.1 - 4.8 6.4 7.0 1.7 7.9 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) EMP24_GP25L PF01105.19 EKX72328.1 - 5.7 6.6 6.4 6.4 6.4 3.6 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Ndufs5 PF10200.4 EKX72328.1 - 6 6.9 8.7 11 6.1 2.0 2.8 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa IncA PF04156.9 EKX72328.1 - 7 6.1 16.0 24 4.4 9.5 2.7 1 1 1 2 2 2 0 IncA protein DNA_primase_lrg PF04104.9 EKX72328.1 - 8.6 5.5 8.5 2.4 7.3 2.2 2.0 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit PFL PF02901.10 EKX72329.1 - 0.049 12.0 3.1 0.061 11.7 2.1 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase Mnd1 PF03962.10 EKX72329.1 - 0.1 12.2 9.2 0.14 11.7 6.4 1.2 1 0 0 1 1 1 0 Mnd1 family Seryl_tRNA_N PF02403.17 EKX72329.1 - 0.14 12.2 12.2 0.25 11.3 8.5 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Not1 PF04054.10 EKX72329.1 - 0.22 10.3 2.0 0.29 9.9 1.4 1.1 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 ProRS-C_2 PF09181.5 EKX72329.1 - 6.9 6.6 6.5 3.8 7.5 0.1 2.8 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal GST_C PF00043.20 EKX72330.1 - 0.0014 18.5 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKX72330.1 - 0.003 18.0 0.0 0.007 16.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1g PF09334.6 EKX72331.1 - 5.7e-108 361.0 0.5 5.3e-107 357.8 0.3 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EKX72331.1 - 6.1e-29 100.4 0.9 3.9e-14 51.5 0.1 3.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EKX72331.1 - 5.6e-11 42.1 0.0 0.00016 20.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EKX72331.1 - 0.00039 19.2 0.0 0.0057 15.3 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (K) NT-C2 PF10358.4 EKX72333.1 - 0.00099 18.6 0.1 0.0015 18.0 0.1 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins FAINT PF04385.10 EKX72334.1 - 2.1e-34 117.1 1.4 2.2e-08 33.8 0.0 6.9 6 1 1 7 7 7 6 Domain of unknown function, DUF529 Focal_AT PF03623.8 EKX72335.1 - 0.0063 16.0 0.7 0.022 14.2 0.5 1.9 1 1 0 1 1 1 1 Focal adhesion targeting region Med4 PF10018.4 EKX72335.1 - 2.2 7.6 7.0 1.8 7.8 3.2 2.0 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Pkinase PF00069.20 EKX72336.1 - 6.2e-65 218.9 0.0 2.6e-64 216.8 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX72336.1 - 1e-30 106.6 0.0 3.4e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EKX72336.1 - 0.00034 19.6 0.0 0.00078 18.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKX72336.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FAINT PF04385.10 EKX72337.1 - 8.4e-34 115.2 19.9 1e-05 25.3 0.8 6.6 6 1 0 6 6 6 6 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72338.1 - 2.1e-16 59.5 0.1 6.9e-05 22.6 0.0 4.6 4 0 0 4 4 4 4 Domain of unknown function, DUF529 EMA PF02488.10 EKX72338.1 - 0.0011 18.4 1.5 0.13 11.7 0.0 2.9 3 0 0 3 3 3 2 Merozoite Antigen SPACA7 PF15307.1 EKX72340.1 - 0.076 13.1 0.6 1.4 9.0 0.0 3.1 3 0 0 3 3 3 0 Sperm acrosome-associated protein 7 Ribosomal_L37ae PF01780.14 EKX72341.1 - 0.18 11.6 1.6 0.44 10.4 1.1 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family FAINT PF04385.10 EKX72342.1 - 3.2e-10 39.7 0.8 7.7e-06 25.6 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72343.1 - 3.5e-06 26.7 2.0 0.025 14.4 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 HEAT_2 PF13646.1 EKX72344.1 - 2.1e-05 24.7 0.0 0.019 15.2 0.0 2.1 1 1 2 3 3 3 2 HEAT repeats Arm PF00514.18 EKX72344.1 - 2.6e-05 23.8 0.0 0.00036 20.2 0.0 2.6 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat WAPL PF07814.8 EKX72344.1 - 0.042 12.5 0.0 0.067 11.9 0.0 1.3 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin Hydrolase_3 PF08282.7 EKX72345.1 - 4.7e-32 111.5 0.0 6.1e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKX72345.1 - 4.6e-05 23.6 0.1 0.0015 18.7 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX72345.1 - 0.00017 21.0 0.0 0.0033 16.7 0.0 2.1 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_6 PF13344.1 EKX72345.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ArsA_ATPase PF02374.10 EKX72346.1 - 1.1e-52 179.0 3.9 2e-44 151.8 0.4 2.0 1 1 1 2 2 2 2 Anion-transporting ATPase Cor1 PF04803.7 EKX72346.1 - 0.012 15.3 0.8 0.012 15.3 0.6 1.8 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region CbiA PF01656.18 EKX72346.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EKX72346.1 - 0.067 13.1 0.5 6.4 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain THOC7 PF05615.8 EKX72346.1 - 0.082 13.1 2.4 0.29 11.4 0.3 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 DUF3453 PF11935.3 EKX72346.1 - 0.15 11.4 1.1 0.65 9.3 0.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3453) DUF1825 PF08855.5 EKX72346.1 - 0.91 9.5 6.5 0.23 11.4 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1825) ArsA_ATPase PF02374.10 EKX72347.1 - 1e-09 37.8 0.3 1.7e-09 37.1 0.2 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EKX72347.1 - 1.3e-06 27.9 0.2 2.3e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 EKX72347.1 - 0.00021 21.5 0.5 0.0026 18.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 EKX72347.1 - 0.0073 15.1 0.0 0.13 11.0 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_26 PF13500.1 EKX72347.1 - 0.02 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EKX72347.1 - 0.032 13.8 0.0 0.096 12.2 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 EKX72347.1 - 0.043 13.4 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EKX72347.1 - 0.047 13.8 0.1 0.23 11.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_31 PF13614.1 EKX72347.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EKX72347.1 - 0.064 14.0 0.0 0.24 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EKX72347.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2782 PF11191.3 EKX72350.1 - 0.14 12.1 0.0 3 7.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) FAINT PF04385.10 EKX72351.1 - 0.00015 21.5 0.7 0.00036 20.3 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function, DUF529 Actino_peptide PF14408.1 EKX72352.1 - 1.4 8.9 6.8 2.7 8.0 4.7 1.4 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes Pox_L3_FP4 PF03339.9 EKX72353.1 - 0.046 12.1 0.2 0.097 11.1 0.0 1.5 2 0 0 2 2 2 0 Poxvirus L3/FP4 protein FAINT PF04385.10 EKX72354.1 - 1.4e-06 28.0 0.0 0.014 15.2 0.0 4.1 4 0 0 4 4 4 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72354.1 - 2.8e-05 23.7 2.7 1.8 7.9 0.2 3.3 3 0 0 3 3 3 3 Merozoite Antigen HMG_box PF00505.14 EKX72354.1 - 0.19 12.0 2.0 0.92 9.8 0.8 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box FAINT PF04385.10 EKX72357.1 - 1.1e-12 47.6 2.6 0.0025 17.5 0.4 3.5 3 0 0 3 3 3 3 Domain of unknown function, DUF529 AAA_11 PF13086.1 EKX72358.1 - 3.2e-31 108.7 0.0 6.1e-15 55.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.1 EKX72358.1 - 8.3e-27 93.8 0.0 3.4e-26 91.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKX72358.1 - 2.2e-07 30.5 0.0 5.7e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EKX72358.1 - 2.6e-06 27.1 0.0 0.0058 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.1 EKX72358.1 - 0.00034 20.6 0.4 0.0016 18.5 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EKX72358.1 - 0.0046 16.3 0.0 0.009 15.3 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 EKX72358.1 - 0.0048 16.9 0.0 0.03 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EKX72358.1 - 0.014 14.8 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EKX72358.1 - 0.017 14.8 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 EKX72358.1 - 0.022 14.3 0.1 1.7 8.1 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EKX72358.1 - 0.037 14.2 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKX72358.1 - 0.051 13.7 0.0 0.31 11.1 0.0 2.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EKX72358.1 - 0.063 13.4 0.0 5.5 7.2 0.0 2.9 2 1 0 2 2 2 0 RNA helicase FAINT PF04385.10 EKX72359.1 - 7.4e-28 96.2 6.6 1.9e-09 37.2 0.0 4.4 4 0 0 4 4 4 4 Domain of unknown function, DUF529 EMA PF02488.10 EKX72359.1 - 0.55 9.6 9.8 0.86 9.0 0.4 3.1 3 1 1 4 4 4 0 Merozoite Antigen Adeno_E3_CR2 PF02439.10 EKX72360.1 - 0.033 13.7 2.6 0.062 12.8 1.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pex14_N PF04695.8 EKX72360.1 - 0.047 13.7 1.0 0.13 12.3 0.7 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Amnionless PF14828.1 EKX72360.1 - 0.063 11.7 0.0 0.11 10.9 0.0 1.4 1 0 0 1 1 1 0 Amnionless zf-piccolo PF05715.8 EKX72360.1 - 0.23 11.4 3.9 0.53 10.3 2.7 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger Mucin PF01456.12 EKX72360.1 - 1.8 8.3 14.1 0.12 12.1 5.7 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein MGC-24 PF05283.6 EKX72360.1 - 1.8 8.2 12.0 0.37 10.5 3.1 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) ERbeta_N PF12497.3 EKX72362.1 - 0.012 15.4 1.3 0.12 12.2 0.6 2.3 2 0 0 2 2 2 0 Estrogen receptor beta Synaptobrevin PF00957.16 EKX72363.1 - 2.9e-11 42.8 0.1 5.1e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Adaptin_N PF01602.15 EKX72364.1 - 9.7e-27 93.4 0.0 1.2e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region DUF1654 PF07867.6 EKX72364.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) TAF4 PF05236.9 EKX72365.1 - 0.025 13.8 0.1 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Adaptin_N PF01602.15 EKX72366.1 - 4.4e-11 41.7 0.3 6e-11 41.3 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region BT1 PF03092.11 EKX72367.1 - 1.1e-52 179.2 21.1 1.9e-52 178.4 14.6 1.3 1 1 0 1 1 1 1 BT1 family FAINT PF04385.10 EKX72368.1 - 1.8e-12 46.9 0.0 9.8e-06 25.3 0.0 3.7 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 EKX72368.1 - 0.027 13.9 3.8 3.9 6.8 0.0 3.7 2 1 1 3 3 3 0 Merozoite Antigen CDC45 PF02724.9 EKX72370.1 - 0.81 7.6 4.1 1.3 7.0 2.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.1 EKX72370.1 - 3.3 7.3 6.0 5.7 6.5 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pox_Ag35 PF03286.9 EKX72370.1 - 4 6.9 10.8 8.6 5.8 7.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Matrilin_ccoil PF10393.4 EKX72371.1 - 1.8 7.9 10.3 0.95 8.8 0.2 4.1 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Hydrolase_3 PF08282.7 EKX72372.1 - 3e-26 92.5 0.0 2.5e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKX72372.1 - 0.00014 22.1 0.0 0.00045 20.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAINT PF04385.10 EKX72373.1 - 3.2e-39 132.6 24.8 2.1e-05 24.2 0.0 11.0 11 0 0 11 11 11 10 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72377.1 - 9.3e-26 89.4 4.0 1.1e-07 31.5 0.0 4.5 4 0 0 4 4 4 4 Domain of unknown function, DUF529 RRM_3 PF08777.6 EKX72378.1 - 0.0068 16.2 0.0 0.0081 15.9 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif RRM_6 PF14259.1 EKX72378.1 - 0.0075 16.2 0.0 0.018 15.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.19 EKX72379.1 - 9.3e-23 80.1 0.0 1.3e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EKX72379.1 - 0.048 13.7 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1183 PF06682.7 EKX72381.1 - 0.069 12.7 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) HpaP PF09483.5 EKX72381.1 - 0.07 13.0 2.9 0.098 12.5 2.0 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) SOG2 PF10428.4 EKX72381.1 - 0.15 10.7 1.4 0.17 10.4 1.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SDA1 PF05285.7 EKX72381.1 - 0.47 9.6 6.7 0.57 9.3 4.6 1.1 1 0 0 1 1 1 0 SDA1 DUF4611 PF15387.1 EKX72381.1 - 0.56 10.3 7.3 1.1 9.4 4.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) TFIIF_alpha PF05793.7 EKX72381.1 - 0.59 8.4 9.3 0.73 8.1 6.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2890 PF11081.3 EKX72381.1 - 4 7.4 8.8 8.7 6.3 6.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Hydrolase_3 PF08282.7 EKX72382.1 - 1.8e-38 132.6 0.1 2.1e-38 132.3 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX72382.1 - 3.2e-06 26.6 0.0 0.033 13.4 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Sugar_tr PF00083.19 EKX72385.1 - 1.5e-53 182.0 34.3 2e-53 181.6 23.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKX72385.1 - 1e-11 44.1 29.5 1e-11 44.1 19.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EKX72385.1 - 1.3e-05 23.6 2.9 2.7e-05 22.5 2.0 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAINT PF04385.10 EKX72386.1 - 5.2e-16 58.2 0.0 6.1e-09 35.6 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 EKX72386.1 - 5.6e-08 32.5 1.2 0.095 12.1 0.1 3.8 3 1 1 4 4 4 3 Merozoite Antigen Corona_S2 PF01601.11 EKX72386.1 - 0.088 10.9 0.7 0.13 10.3 0.5 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF706 PF05153.10 EKX72387.1 - 0.0051 16.1 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF706) Cadherin_2 PF08266.7 EKX72387.1 - 0.09 12.3 0.1 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 Cadherin-like FAINT PF04385.10 EKX72391.1 - 9.6e-30 102.2 13.4 2.2e-06 27.3 0.0 7.2 7 0 0 7 7 7 6 Domain of unknown function, DUF529 DUF3883 PF13020.1 EKX72393.1 - 0.025 14.3 0.4 3.4 7.4 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3883) FAINT PF04385.10 EKX72394.1 - 2e-09 37.1 0.0 0.00042 20.0 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 EKX72394.1 - 0.062 12.7 0.0 0.2 11.0 0.0 1.6 1 1 0 1 1 1 0 Merozoite Antigen AP2 PF00847.15 EKX72395.1 - 0.043 13.9 0.5 0.069 13.3 0.3 1.3 1 0 0 1 1 1 0 AP2 domain Nop14 PF04147.7 EKX72395.1 - 0.096 10.5 3.1 0.086 10.7 2.2 1.0 1 0 0 1 1 1 0 Nop14-like family Bd3614-deam PF14439.1 EKX72395.1 - 1 9.2 5.7 1.6 8.6 4.0 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase DUF2890 PF11081.3 EKX72395.1 - 2.1 8.3 7.4 2.5 8.0 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CENP-B_dimeris PF09026.5 EKX72395.1 - 5.1 7.3 15.2 7.7 6.8 10.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BT1 PF03092.11 EKX72396.1 - 2.5e-53 181.3 27.3 3.9e-53 180.7 18.9 1.3 1 1 0 1 1 1 1 BT1 family MFS_1 PF07690.11 EKX72396.1 - 1.1e-06 27.5 19.9 1.1e-06 27.5 13.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FAINT PF04385.10 EKX72397.1 - 1.3e-08 34.5 0.1 0.00013 21.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72399.1 - 0.024 14.4 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72400.1 - 3.5e-12 45.9 0.6 3.5e-12 45.9 0.4 1.4 2 0 0 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72401.1 - 0.00097 18.9 0.1 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72402.1 - 0.074 12.9 0.6 0.5 10.2 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function, DUF529 5_nucleotid PF05761.9 EKX72402.1 - 0.089 11.2 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family Laminin_G_2 PF02210.19 EKX72402.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain Abhydrolase_6 PF12697.2 EKX72403.1 - 3e-11 43.6 0.0 5.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX72403.1 - 2e-09 37.3 0.0 4.8e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family FAINT PF04385.10 EKX72403.1 - 5.1e-09 35.8 6.8 1.4e-05 24.8 0.0 3.8 4 0 0 4 4 4 2 Domain of unknown function, DUF529 Hydrolase_4 PF12146.3 EKX72403.1 - 4.1e-07 29.7 0.0 1.9e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EKX72403.1 - 0.029 13.9 0.0 0.07 12.6 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0565 PF10561.4 EKX72403.1 - 0.031 13.1 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Peptidase_S9 PF00326.16 EKX72403.1 - 0.071 12.3 0.3 1.4 8.0 0.1 2.8 3 0 0 3 3 3 0 Prolyl oligopeptidase family ATPase-cat_bd PF12156.3 EKX72404.1 - 0.16 12.5 0.1 0.39 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase YejG PF13989.1 EKX72407.1 - 0.0037 17.3 0.0 0.0086 16.1 0.0 1.6 1 0 0 1 1 1 1 YejG-like protein SRP1_TIP1 PF00660.12 EKX72407.1 - 0.025 14.3 0.3 0.34 10.7 0.0 2.7 3 0 0 3 3 3 0 Seripauperin and TIP1 family MRJP PF03022.11 EKX72407.1 - 0.041 13.1 0.1 0.065 12.4 0.1 1.2 1 0 0 1 1 1 0 Major royal jelly protein FAINT PF04385.10 EKX72408.1 - 1.1e-15 57.1 0.5 3.5e-07 29.9 0.2 3.3 3 0 0 3 3 3 3 Domain of unknown function, DUF529 AhpC-TSA PF00578.16 EKX72410.1 - 0.047 13.3 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family BRX_N PF13713.1 EKX72410.1 - 0.12 11.9 0.2 0.24 10.9 0.2 1.5 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain FAINT PF04385.10 EKX72412.1 - 5.4e-05 22.9 0.0 0.00018 21.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72414.1 - 5.6e-30 103.0 6.5 2.7e-08 33.5 0.1 6.1 5 1 1 6 6 6 5 Domain of unknown function, DUF529 EMA PF02488.10 EKX72414.1 - 1.6e-07 31.0 13.7 0.0005 19.6 3.0 3.6 2 1 0 3 3 3 3 Merozoite Antigen Saf-Nte_pilin PF09460.5 EKX72414.1 - 0.023 14.4 3.0 3.4 7.4 0.0 4.1 3 1 0 4 4 4 0 Saf-pilin pilus formation protein Flavi_capsid PF01003.14 EKX72414.1 - 0.31 10.5 2.4 4.2 6.9 0.0 3.5 4 0 0 4 4 4 0 Flavivirus capsid protein C PI-PLC-X PF00388.14 EKX72415.1 - 0.053 12.9 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Histone PF00125.19 EKX72416.1 - 2.7e-33 113.9 0.5 4.7e-33 113.1 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EKX72416.1 - 7.7e-05 22.8 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EKX72416.1 - 0.0061 16.5 1.1 0.0084 16.1 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EKX72416.1 - 0.041 13.6 0.3 0.079 12.7 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit FAINT PF04385.10 EKX72417.1 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function, DUF529 DUF2567 PF10821.3 EKX72418.1 - 0.72 9.3 4.1 0.99 8.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2567) FAINT PF04385.10 EKX72420.1 - 0.0053 16.5 0.0 1.1 9.1 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72421.1 - 1.4e-21 76.1 0.0 1.6e-05 24.6 0.0 4.7 4 1 0 4 4 4 4 Domain of unknown function, DUF529 EMA PF02488.10 EKX72421.1 - 5.9e-07 29.2 4.1 0.00042 19.8 0.7 3.1 3 0 0 3 3 3 2 Merozoite Antigen Flavi_capsid PF01003.14 EKX72421.1 - 0.19 11.2 1.1 13 5.3 0.0 2.9 3 0 0 3 3 3 0 Flavivirus capsid protein C ABC_tran PF00005.22 EKX72422.1 - 9.6e-31 106.8 0.0 4.5e-17 62.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_23 PF13476.1 EKX72422.1 - 1.7e-06 28.5 2.6 0.017 15.4 0.2 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EKX72422.1 - 1.4e-05 25.1 0.2 0.023 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EKX72422.1 - 3.3e-05 23.3 1.5 0.071 12.6 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EKX72422.1 - 5.4e-05 23.5 0.1 0.13 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EKX72422.1 - 0.00014 22.6 0.0 0.11 13.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EKX72422.1 - 0.00016 21.7 0.3 0.021 14.8 0.0 5.1 7 0 0 7 7 6 2 AAA domain AAA_25 PF13481.1 EKX72422.1 - 0.00022 20.6 0.0 0.062 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EKX72422.1 - 0.00027 20.5 0.1 0.1 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EKX72422.1 - 0.0012 17.7 0.3 0.0033 16.2 0.0 1.7 2 0 0 2 2 2 1 ArgK protein FtsK_SpoIIIE PF01580.13 EKX72422.1 - 0.0018 17.7 0.2 0.57 9.6 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 EKX72422.1 - 0.0022 16.9 0.4 1.6 7.5 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 EKX72422.1 - 0.0023 17.1 0.1 0.27 10.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF87 PF01935.12 EKX72422.1 - 0.0032 17.3 3.5 0.035 13.9 0.0 2.6 3 0 0 3 3 2 1 Domain of unknown function DUF87 MobB PF03205.9 EKX72422.1 - 0.0046 16.6 0.2 0.66 9.6 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EKX72422.1 - 0.0053 16.3 0.5 0.18 11.4 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EKX72422.1 - 0.0055 15.8 0.2 2.5 7.1 0.1 2.5 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 EKX72422.1 - 0.0056 16.3 0.5 2.2 7.8 0.1 2.5 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 EKX72422.1 - 0.0076 15.5 0.4 0.16 11.2 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EKX72422.1 - 0.0095 16.0 0.1 4 7.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EKX72422.1 - 0.0098 16.3 0.1 4.5 7.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_19 PF13245.1 EKX72422.1 - 0.015 15.0 1.1 3.3 7.5 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain MMR_HSR1 PF01926.18 EKX72422.1 - 0.03 14.2 0.6 0.22 11.5 0.0 2.6 3 0 0 3 3 2 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 EKX72422.1 - 0.056 12.0 0.2 5 5.6 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 EKX72422.1 - 0.06 12.8 0.1 8.9 5.7 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 EKX72422.1 - 0.062 12.7 0.2 1.5 8.2 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein NTPase_1 PF03266.10 EKX72422.1 - 0.073 12.7 0.2 5.4 6.6 0.1 2.4 2 0 0 2 2 2 0 NTPase cobW PF02492.14 EKX72422.1 - 0.091 12.1 1.4 11 5.4 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.10 EKX72422.1 - 0.094 11.5 0.1 3.9 6.2 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_10 PF12846.2 EKX72422.1 - 0.13 11.6 0.3 8.2 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EKX72422.1 - 0.16 11.8 0.1 7.3 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Disintegrin PF00200.18 EKX72422.1 - 0.19 11.9 1.2 0.35 11.1 0.9 1.4 1 0 0 1 1 1 0 Disintegrin Dynamin_N PF00350.18 EKX72422.1 - 0.22 11.3 3.0 4.4 7.0 0.0 2.8 3 0 0 3 3 3 0 Dynamin family AAA_28 PF13521.1 EKX72422.1 - 0.41 10.6 0.9 21 5.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain FAINT PF04385.10 EKX72423.1 - 7.9e-05 22.4 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 EMA PF02488.10 EKX72423.1 - 0.0011 18.5 0.1 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Merozoite Antigen Peptidase_S6 PF02395.11 EKX72423.1 - 0.018 13.1 0.1 0.022 12.9 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin A1 protease FAINT PF04385.10 EKX72424.1 - 0.013 15.3 0.1 0.03 14.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function, DUF529 ThiC PF01964.13 EKX72424.1 - 0.15 10.5 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 ThiC family eIF3_subunit PF08597.5 EKX72426.1 - 1.9e-07 30.9 9.2 3.2e-07 30.1 6.4 1.4 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit Ole-e-6 PF09253.5 EKX72426.1 - 0.063 12.9 3.2 1 9.0 0.1 2.6 2 0 0 2 2 2 0 Pollen allergen ole e 6 Sirohm_synth_C PF14823.1 EKX72427.1 - 0.012 14.9 0.1 0.012 14.9 0.0 2.4 4 0 0 4 4 4 0 Sirohaem biosynthesis protein C-terminal MRP-L47 PF06984.8 EKX72427.1 - 0.065 13.1 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Hydrolase_3 PF08282.7 EKX72428.1 - 1.5e-33 116.4 0.0 3.2e-33 115.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GWT1 PF06423.7 EKX72428.1 - 1.9e-10 40.9 7.9 1.9e-10 40.9 5.5 2.2 2 0 0 2 2 2 1 GWT1 HAD PF12710.2 EKX72428.1 - 0.0095 16.1 0.1 0.039 14.1 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX72428.1 - 0.012 14.9 0.0 0.033 13.4 0.0 1.6 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase D-aminoacyl_C PF07908.7 EKX72428.1 - 0.19 11.0 0.2 0.51 9.6 0.1 1.7 1 0 0 1 1 1 0 D-aminoacylase, C-terminal region ATPase-cat_bd PF12156.3 EKX72429.1 - 0.16 12.5 0.1 0.39 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase FAINT PF04385.10 EKX72430.1 - 2.4e-15 56.1 6.3 0.00021 21.0 0.5 3.6 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX72430.1 - 3.3e-13 50.0 0.0 6.2e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX72430.1 - 7e-09 35.5 0.0 1.7e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX72430.1 - 7.7e-07 28.8 0.1 2.1e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EKX72430.1 - 0.0064 15.9 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EKX72430.1 - 0.03 13.8 0.1 0.088 12.3 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold FAINT PF04385.10 EKX72432.1 - 7.3e-08 32.1 0.9 0.0044 16.8 0.3 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72432.1 - 0.011 15.2 0.5 0.02 14.3 0.3 1.4 1 0 0 1 1 1 0 Merozoite Antigen Pam17 PF08566.5 EKX72432.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 DEDD_Tnp_IS110 PF01548.12 EKX72432.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Transposase VCBS PF13517.1 EKX72435.1 - 0.077 13.3 0.1 0.24 11.7 0.1 1.9 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FAINT PF04385.10 EKX72436.1 - 1.7e-19 69.4 8.1 1.9e-08 34.0 0.4 3.9 4 0 0 4 4 4 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX72436.1 - 2.7e-13 50.3 0.0 5.4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX72436.1 - 1.3e-10 41.2 0.0 3e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family EMA PF02488.10 EKX72436.1 - 1.3e-08 34.6 0.0 0.00013 21.5 0.0 2.9 1 1 2 3 3 3 2 Merozoite Antigen Hydrolase_4 PF12146.3 EKX72436.1 - 6.2e-07 29.1 3.6 5.9e-06 26.0 0.7 3.1 2 1 1 3 3 3 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EKX72436.1 - 0.00064 19.0 0.0 0.0037 16.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EKX72436.1 - 0.0035 16.8 0.0 0.97 8.8 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase UPF0565 PF10561.4 EKX72436.1 - 0.025 13.5 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 LIP PF03583.9 EKX72436.1 - 0.039 13.1 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Methyltransf_23 PF13489.1 EKX72436.1 - 0.045 13.4 0.0 0.18 11.5 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Abhydrolase_3 PF07859.8 EKX72436.1 - 0.13 11.8 0.0 0.7 9.4 0.0 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold MIF4G PF02854.14 EKX72437.1 - 0.053 12.9 0.6 0.59 9.5 0.1 2.2 1 1 1 2 2 2 0 MIF4G domain Tup_N PF08581.5 EKX72437.1 - 0.095 12.9 0.5 0.99 9.6 0.0 2.2 2 0 0 2 2 2 0 Tup N-terminal FAINT PF04385.10 EKX72438.1 - 0.00013 21.6 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Collagen PF01391.13 EKX72439.1 - 1.2e-07 31.1 26.6 1.2e-07 31.1 18.4 3.0 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) Syndecan PF01034.15 EKX72440.1 - 0.0079 15.8 0.3 0.02 14.5 0.2 1.6 1 0 0 1 1 1 1 Syndecan domain FAM101 PF15068.1 EKX72440.1 - 0.2 11.0 4.3 0.31 10.4 3.0 1.3 1 0 0 1 1 1 0 FAM101 family Zn-ribbon_8 PF09723.5 EKX72440.1 - 3.6 7.6 8.6 3.5 7.6 0.1 2.8 3 0 0 3 3 3 0 Zinc ribbon domain Choline_kinase PF01633.15 EKX72441.1 - 2.1e-38 132.0 0.0 2.9e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EKX72441.1 - 4.7e-13 49.4 0.0 8.1e-13 48.6 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EKX72441.1 - 6.5e-05 22.2 0.1 0.00011 21.4 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase PapJ PF14855.1 EKX72443.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.3 1 1 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone FAINT PF04385.10 EKX72444.1 - 1e-14 54.0 0.0 2.5e-09 36.8 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Baculo_p24 PF05073.7 EKX72445.1 - 0.096 12.2 1.2 0.38 10.2 0.1 2.1 2 0 0 2 2 2 0 Baculovirus P24 capsid protein FUSC PF04632.7 EKX72445.1 - 0.13 10.6 0.2 0.2 10.0 0.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TarH PF02203.10 EKX72445.1 - 0.15 11.8 5.0 0.07 12.9 0.4 2.3 2 0 0 2 2 2 0 Tar ligand binding domain homologue DUF2422 PF10337.4 EKX72445.1 - 1.7 7.3 6.8 0.8 8.4 3.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) Syntaxin-6_N PF09177.6 EKX72445.1 - 6.1 7.3 12.4 0.18 12.2 1.6 2.9 3 0 0 3 3 3 0 Syntaxin 6, N-terminal TMPIT PF07851.8 EKX72445.1 - 6.9 5.6 10.4 0.09 11.8 1.6 1.9 2 1 0 2 2 2 0 TMPIT-like protein FAINT PF04385.10 EKX72446.1 - 0.017 14.9 0.3 0.025 14.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function, DUF529 AAA_2 PF07724.9 EKX72449.1 - 6.8e-54 182.3 0.0 4.2e-51 173.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EKX72449.1 - 1.1e-23 82.9 0.1 9.8e-23 79.8 0.0 2.8 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EKX72449.1 - 2.3e-22 79.5 0.0 2.1e-11 44.1 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKX72449.1 - 2.4e-16 59.7 0.1 4e-11 42.8 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EKX72449.1 - 3.4e-09 36.9 2.3 0.027 14.5 0.0 4.8 4 2 0 4 4 3 2 AAA domain AAA_16 PF13191.1 EKX72449.1 - 7e-09 35.9 4.5 0.00024 21.1 0.0 4.8 4 3 0 6 6 5 2 AAA ATPase domain Sigma54_activat PF00158.21 EKX72449.1 - 1.9e-08 33.9 0.0 7.2e-06 25.5 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EKX72449.1 - 3.6e-08 33.3 0.0 0.0079 16.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EKX72449.1 - 8.4e-07 29.8 0.6 0.021 15.6 0.0 4.0 2 2 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EKX72449.1 - 4.1e-06 27.1 1.5 0.066 13.5 0.0 3.7 4 0 0 4 4 3 2 AAA domain RuvB_N PF05496.7 EKX72449.1 - 7.3e-06 25.1 3.7 0.012 14.6 0.0 3.7 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EKX72449.1 - 1.2e-05 24.8 0.0 0.14 11.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Torsin PF06309.6 EKX72449.1 - 3e-05 23.9 0.0 8.9e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Torsin Arch_ATPase PF01637.13 EKX72449.1 - 3.4e-05 23.6 11.4 0.028 14.1 0.2 5.4 4 2 2 6 6 5 2 Archaeal ATPase RNA_helicase PF00910.17 EKX72449.1 - 0.00016 21.8 0.0 0.38 10.9 0.0 3.1 3 0 0 3 3 2 1 RNA helicase Mg_chelatase PF01078.16 EKX72449.1 - 0.00051 19.2 0.0 0.62 9.1 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EKX72449.1 - 0.00052 19.7 0.0 0.38 10.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EKX72449.1 - 0.00094 18.8 0.0 0.43 10.3 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain MobB PF03205.9 EKX72449.1 - 0.00094 18.9 0.0 0.29 10.8 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EKX72449.1 - 0.001 19.3 0.5 0.19 11.9 0.0 3.5 3 1 0 3 3 3 1 ABC transporter NTPase_1 PF03266.10 EKX72449.1 - 0.0014 18.3 0.9 6.4 6.4 0.0 4.1 4 0 0 4 4 4 0 NTPase Zeta_toxin PF06414.7 EKX72449.1 - 0.0014 17.7 0.0 0.055 12.5 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 EKX72449.1 - 0.0015 17.7 0.0 1.3 8.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_24 PF13479.1 EKX72449.1 - 0.0022 17.5 0.0 2.2 7.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EKX72449.1 - 0.0058 16.2 0.0 2.7 7.5 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EKX72449.1 - 0.009 15.6 0.0 3.2 7.3 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EKX72449.1 - 0.0093 15.4 1.6 0.44 9.9 0.0 3.4 3 1 0 3 3 3 1 AAA-like domain Bac_DnaA PF00308.13 EKX72449.1 - 0.0094 15.6 0.0 4.3 6.9 0.0 3.3 3 0 0 3 3 3 0 Bacterial dnaA protein ResIII PF04851.10 EKX72449.1 - 0.014 15.2 0.1 1 9.1 0.0 3.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EKX72449.1 - 0.018 14.4 0.0 1.3 8.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.1 EKX72449.1 - 0.02 14.5 0.0 0.11 12.1 0.0 2.2 2 1 0 2 2 1 0 DNA polymerase III, delta subunit UBN2 PF14223.1 EKX72449.1 - 0.024 14.4 1.1 0.34 10.6 0.4 2.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type PduV-EutP PF10662.4 EKX72449.1 - 0.037 13.4 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EKX72449.1 - 0.04 13.8 0.0 6.9 6.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 EKX72449.1 - 0.076 13.5 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 EKX72449.1 - 0.1 12.5 0.0 6 6.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.12 EKX72449.1 - 0.17 11.6 6.7 0.69 9.6 0.0 4.1 4 1 1 5 5 4 0 Domain of unknown function DUF87 AAA_23 PF13476.1 EKX72449.1 - 1.5 9.1 4.6 1.5e+02 2.5 0.0 3.5 2 1 0 2 2 2 0 AAA domain FAINT PF04385.10 EKX72451.1 - 7.5e-15 54.5 0.5 3.3e-07 30.0 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function, DUF529 HTH_Tnp_Tc3_1 PF11427.3 EKX72452.1 - 0.11 12.1 0.0 0.46 10.1 0.0 2.0 2 0 0 2 2 2 0 Tc3 transposase AdoHcyase PF05221.12 EKX72454.1 - 8.1e-83 277.4 0.0 1e-82 277.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EKX72454.1 - 9.2e-57 191.4 2.9 1.3e-56 190.9 2.0 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EKX72454.1 - 4.9e-08 32.3 0.4 1.1e-07 31.2 0.3 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EKX72454.1 - 0.00055 19.3 0.4 0.00092 18.6 0.3 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 EKX72454.1 - 0.0061 16.8 0.3 0.013 15.7 0.2 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EKX72454.1 - 0.0091 15.5 2.2 0.027 14.0 0.7 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EKX72454.1 - 0.017 15.1 0.4 0.043 13.9 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 EKX72454.1 - 0.023 13.8 1.5 0.16 11.0 1.1 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.13 EKX72454.1 - 0.047 13.6 1.0 0.12 12.3 0.7 1.8 1 1 0 1 1 1 0 TrkA-N domain VSP PF03302.8 EKX72455.1 - 0.11 11.1 0.2 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF2507 PF10702.4 EKX72456.1 - 0.21 11.2 0.0 0.62 9.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) Btz PF09405.5 EKX72457.1 - 0.15 12.1 5.7 0.091 12.8 2.3 1.8 1 1 1 2 2 2 0 CASC3/Barentsz eIF4AIII binding F-box PF00646.28 EKX72459.1 - 6.9e-05 22.3 1.4 0.00019 21.0 0.3 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EKX72459.1 - 0.0027 17.4 0.9 0.0075 15.9 0.6 1.8 1 0 0 1 1 1 1 F-box-like Phosphoprotein PF00922.12 EKX72459.1 - 0.044 12.9 0.4 0.057 12.6 0.2 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Methyltransf_13 PF08421.6 EKX72461.1 - 0.0026 17.2 0.2 0.0085 15.5 0.1 1.9 2 0 0 2 2 2 1 Putative zinc binding domain Trypan_PARP PF05887.6 EKX72464.1 - 8.4 6.2 20.8 18 5.1 14.4 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAINT PF04385.10 EKX72465.1 - 2.5e-21 75.3 13.5 5.8e-07 29.2 0.3 4.4 5 0 0 5 5 5 3 Domain of unknown function, DUF529 DUF2716 PF10898.3 EKX72465.1 - 0.1 12.6 0.1 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) DUF2981 PF11200.3 EKX72467.1 - 0.011 14.8 0.1 0.02 13.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2981) CotJB PF12652.2 EKX72467.1 - 0.026 14.5 0.3 0.044 13.8 0.2 1.5 1 0 0 1 1 1 0 CotJB protein FAINT PF04385.10 EKX72468.1 - 1.1e-16 60.3 0.2 5.2e-07 29.4 0.2 2.6 2 1 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72468.1 - 1.2e-06 28.2 10.3 0.0047 16.4 0.8 2.1 1 1 1 2 2 2 2 Merozoite Antigen Tox-SHH PF15652.1 EKX72468.1 - 0.021 15.4 0.3 0.24 11.9 0.1 2.2 2 0 0 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature FAINT PF04385.10 EKX72469.1 - 2.8e-95 312.2 83.6 4.2e-07 29.7 0.1 18.6 18 0 0 18 18 18 18 Domain of unknown function, DUF529 Saf-Nte_pilin PF09460.5 EKX72469.1 - 0.00045 20.0 7.4 0.15 11.8 0.0 6.0 6 0 0 6 6 6 2 Saf-pilin pilus formation protein C1_3 PF07649.7 EKX72470.1 - 0.0096 15.9 0.5 1.4 9.0 0.0 2.7 2 0 0 2 2 2 1 C1-like domain Romo1 PF10247.4 EKX72470.1 - 0.085 13.0 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Elf1 PF05129.8 EKX72470.1 - 0.35 10.5 7.1 0.37 10.5 0.9 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like C1_2 PF03107.11 EKX72470.1 - 1.1 9.4 8.2 3.2 7.9 0.1 3.6 3 0 0 3 3 3 0 C1 domain zf-CHY PF05495.7 EKX72470.1 - 5.8 7.1 10.0 1.6 8.9 2.1 2.5 2 0 0 2 2 2 0 CHY zinc finger HhH-GPD PF00730.20 EKX72474.1 - 5.7e-22 78.0 0.0 9.5e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EKX72474.1 - 9.5e-10 37.6 0.3 7.1e-09 34.8 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_2 PF12826.2 EKX72474.1 - 0.18 11.7 0.0 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Ribosomal_L19e PF01280.15 EKX72475.1 - 2.7e-58 195.9 4.7 2.7e-58 195.9 3.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L19e EPO_TPO PF00758.13 EKX72475.1 - 0.0069 16.0 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Erythropoietin/thrombopoietin SAC3_GANP PF03399.11 EKX72476.1 - 3.6e-19 69.1 0.2 4.9e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EKX72476.1 - 6.8e-17 61.5 0.2 5.7e-15 55.3 0.0 2.2 2 0 0 2 2 2 2 COP9 signalosome, subunit CSN8 Fe_hyd_lg_C PF02906.9 EKX72477.1 - 2.4e-52 177.9 0.0 5.2e-51 173.6 0.0 2.2 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain ABC_tran PF00005.22 EKX72478.1 - 6.9e-29 100.9 0.0 4.6e-13 49.6 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EKX72478.1 - 1.9e-12 47.1 6.6 1.9e-12 47.1 4.6 2.7 3 0 0 3 3 3 1 ABC transporter transmembrane region DUF258 PF03193.11 EKX72478.1 - 1.3e-07 30.9 0.1 0.016 14.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EKX72478.1 - 2.1e-07 31.4 0.0 0.029 14.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EKX72478.1 - 7.7e-07 28.5 0.9 0.011 15.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 EKX72478.1 - 6.6e-06 25.7 1.2 0.067 12.6 0.0 3.7 4 0 0 4 4 4 1 AAA-like domain MMR_HSR1 PF01926.18 EKX72478.1 - 7.9e-06 25.8 0.0 0.088 12.7 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 EKX72478.1 - 1.5e-05 25.1 0.7 0.32 10.8 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 EKX72478.1 - 2.1e-05 25.3 0.2 0.27 12.0 0.0 3.6 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EKX72478.1 - 6.6e-05 23.2 0.2 0.53 10.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EKX72478.1 - 8.1e-05 22.1 0.1 0.27 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EKX72478.1 - 0.00017 21.7 0.5 4.9 7.3 0.1 3.5 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.14 EKX72478.1 - 0.00048 19.4 3.7 0.025 13.8 0.1 3.9 5 0 0 5 5 5 1 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.18 EKX72478.1 - 0.00069 19.4 2.8 0.4 10.4 0.0 3.3 3 0 0 3 3 3 2 Dynamin family Miro PF08477.8 EKX72478.1 - 0.00088 19.7 1.8 0.33 11.4 0.1 2.9 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 EKX72478.1 - 0.00091 18.2 0.4 0.062 12.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 EKX72478.1 - 0.0018 18.0 0.4 0.38 10.4 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EKX72478.1 - 0.0024 17.8 0.8 0.32 10.9 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain ArgK PF03308.11 EKX72478.1 - 0.011 14.4 0.4 0.051 12.3 0.0 2.0 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 EKX72478.1 - 0.02 14.3 1.9 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EKX72478.1 - 0.021 14.5 1.7 1.4 8.5 0.1 3.3 3 1 0 3 3 3 0 Archaeal ATPase IstB_IS21 PF01695.12 EKX72478.1 - 0.027 13.8 1.0 1.4 8.2 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.1 EKX72478.1 - 0.034 14.0 0.3 3.5 7.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.1 EKX72478.1 - 0.058 12.9 0.4 19 4.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 EKX72478.1 - 0.059 12.8 2.3 1.8 8.0 0.1 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 EKX72478.1 - 0.059 12.4 0.1 5.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin UPF0079 PF02367.12 EKX72478.1 - 0.064 12.8 0.3 4.8 6.8 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 Helicase_RecD PF05127.9 EKX72478.1 - 0.093 12.3 0.0 0.31 10.6 0.0 1.9 1 0 0 1 1 1 0 Helicase cobW PF02492.14 EKX72478.1 - 0.16 11.4 1.6 12 5.3 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Hydrolase_3 PF08282.7 EKX72479.1 - 3.6e-26 92.2 0.0 5.8e-26 91.6 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX72479.1 - 5.6e-05 22.5 0.0 0.1 11.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase VCBS PF13517.1 EKX72480.1 - 0.14 12.5 0.1 0.36 11.2 0.1 1.7 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FAINT PF04385.10 EKX72481.1 - 1.6e-18 66.2 0.0 2.6e-05 24.0 0.3 3.4 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Podoplanin PF05808.6 EKX72485.1 - 0.037 13.5 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Podoplanin HEXIM PF15313.1 EKX72486.1 - 0.066 13.3 1.4 0.085 13.0 1.0 1.2 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein Prosystemin PF07376.6 EKX72486.1 - 2.1 7.6 7.5 4.1 6.7 5.2 1.5 1 1 0 1 1 1 0 Prosystemin DUF3595 PF12166.3 EKX72487.1 - 0.004 16.0 0.0 0.0053 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) Na_Ala_symp PF01235.12 EKX72487.1 - 1.4 7.4 9.0 1.8 7.0 6.2 1.0 1 0 0 1 1 1 0 Sodium:alanine symporter family DnaJ-X PF14308.1 EKX72489.1 - 0.0052 16.0 0.0 0.0099 15.1 0.0 1.5 1 0 0 1 1 1 1 X-domain of DnaJ-containing Sugar_tr PF00083.19 EKX72493.1 - 1.6e-60 204.9 34.0 2e-60 204.6 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKX72493.1 - 7.1e-12 44.6 36.0 6e-08 31.7 9.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EKX72493.1 - 4.1e-05 21.9 2.9 4.1e-05 21.9 2.0 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2668 PF10873.3 EKX72493.1 - 4.3 7.4 8.0 0.42 10.7 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2668) Duffy_binding PF05424.6 EKX72494.1 - 0.024 14.4 5.1 0.32 10.7 0.0 2.3 1 1 0 2 2 2 0 Duffy binding domain Retrotrans_gag PF03732.12 EKX72494.1 - 0.47 10.5 3.3 2 8.5 0.3 2.7 2 1 1 3 3 3 0 Retrotransposon gag protein FAINT PF04385.10 EKX72496.1 - 7.1e-05 22.5 0.3 0.05 13.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72497.1 - 1.9e-10 40.4 0.3 0.00056 19.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Beta-Casp PF10996.3 EKX72498.1 - 3.8e-22 78.5 0.0 8.3e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.2 EKX72498.1 - 5.3e-14 52.2 0.1 3.4e-12 46.3 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EKX72498.1 - 1.1e-13 50.7 0.0 2.2e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EKX72498.1 - 1.9e-09 37.4 0.9 5.2e-08 32.7 0.6 2.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily FtsJ PF01728.14 EKX72499.1 - 1.3e-30 106.7 0.0 5.3e-23 81.9 0.0 2.5 2 0 0 2 2 2 2 FtsJ-like methyltransferase Methyltrans_Mon PF14314.1 EKX72499.1 - 4.5e-07 28.1 1.9 0.0022 15.9 0.3 2.3 2 0 0 2 2 2 2 Virus-capping methyltransferase Pox_mRNA-cap PF03341.8 EKX72499.1 - 0.026 13.5 3.5 0.054 12.5 0.2 2.5 2 0 0 2 2 2 0 Poxvirus mRNA capping enzyme, small subunit DUF4303 PF14136.1 EKX72502.1 - 0.022 14.4 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) DUF4649 PF15507.1 EKX72502.1 - 0.05 13.3 0.7 11 5.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4649) FAINT PF04385.10 EKX72505.1 - 3.5e-10 39.5 0.2 5.1e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function, DUF529 SOG2 PF10428.4 EKX72505.1 - 0.34 9.5 3.4 0.42 9.2 2.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FAINT PF04385.10 EKX72506.1 - 1.6e-06 27.8 5.8 0.00036 20.3 0.1 3.1 3 1 1 4 4 4 2 Domain of unknown function, DUF529 Baculo_IE-1 PF05290.6 EKX72506.1 - 0.04 13.6 0.1 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) MarR_2 PF12802.2 EKX72508.1 - 0.0065 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.1 EKX72508.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Big_4 PF07532.6 EKX72508.1 - 0.025 14.1 0.8 0.045 13.2 0.6 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) OAD_gamma PF04277.8 EKX72510.1 - 0.041 14.2 0.2 0.041 14.2 0.1 6.3 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CAP_C PF08603.6 EKX72511.1 - 1.6e-38 131.5 2.8 2.8e-38 130.7 1.9 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EKX72511.1 - 0.029 13.7 2.9 0.066 12.6 2.0 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor C Imm6 PF14434.1 EKX72511.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Immunity protein Imm6 CAV_VP3 PF04771.7 EKX72511.1 - 0.13 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein Abhydrolase_6 PF12697.2 EKX72512.1 - 2.7e-13 50.3 0.0 5.1e-12 46.1 0.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family FAINT PF04385.10 EKX72512.1 - 2.8e-10 39.9 3.1 2.5e-06 27.2 0.0 4.6 4 1 1 5 5 5 1 Domain of unknown function, DUF529 Hydrolase_4 PF12146.3 EKX72512.1 - 5.1e-10 39.0 1.0 1.3e-08 34.6 0.2 3.1 3 0 0 3 3 3 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EKX72512.1 - 1.6e-08 34.3 0.0 4.7e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKX72512.1 - 0.00036 19.8 0.1 0.0016 17.7 0.0 2.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EKX72512.1 - 0.04 13.4 0.0 0.22 11.0 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EKX72512.1 - 0.059 12.9 0.0 2.9 7.3 0.0 2.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold FAINT PF04385.10 EKX72515.1 - 5.4e-14 51.8 7.0 1.8e-05 24.4 0.1 3.7 3 1 0 3 3 3 3 Domain of unknown function, DUF529 DUF4362 PF14275.1 EKX72515.1 - 0.063 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) FAINT PF04385.10 EKX72516.1 - 3e-06 26.9 4.9 0.07 12.9 1.1 3.8 4 0 0 4 4 4 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72516.1 - 0.023 14.2 0.4 0.48 9.8 0.0 2.4 2 0 0 2 2 2 0 Merozoite Antigen SAP PF02037.22 EKX72517.1 - 8.8e-12 44.2 0.2 2.6e-11 42.7 0.1 1.9 1 0 0 1 1 1 1 SAP domain Peptidase_C37 PF05416.7 EKX72517.1 - 0.0084 14.4 1.6 0.0091 14.3 1.1 1.1 1 0 0 1 1 1 1 Southampton virus-type processing peptidase PhoD PF09423.5 EKX72518.1 - 1.4e-08 33.7 0.0 2.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD PF09423.5 EKX72519.1 - 0.0013 17.3 0.1 0.0013 17.3 0.1 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Acetyltransf_9 PF13527.1 EKX72520.1 - 0.071 12.9 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain BIR PF00653.16 EKX72521.1 - 0.21 12.0 3.3 0.45 10.9 2.3 1.5 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain Methyltransf_16 PF10294.4 EKX72523.1 - 0.038 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FAINT PF04385.10 EKX72528.1 - 6.6e-23 80.3 8.1 3.9e-05 23.4 0.0 6.3 6 1 0 6 6 6 5 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72529.1 - 0.0003 20.5 0.1 0.00069 19.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function, DUF529 EMA PF02488.10 EKX72529.1 - 0.008 15.6 0.1 1.6 8.1 0.0 2.2 2 0 0 2 2 2 2 Merozoite Antigen DUF3312 PF11768.3 EKX72532.1 - 0.079 11.1 0.6 0.092 10.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Cytochrom_B561 PF03188.11 EKX72532.1 - 0.11 12.2 1.1 0.2 11.4 0.0 1.8 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 DUF1211 PF06736.6 EKX72532.1 - 2.2 8.4 8.5 75 3.5 5.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1211) Cpn60_TCP1 PF00118.19 EKX72535.1 - 6.7e-142 473.5 8.5 7.5e-142 473.3 5.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L37ae PF01780.14 EKX72536.1 - 0.0087 15.9 0.4 0.39 10.6 0.1 2.3 2 0 0 2 2 2 1 Ribosomal L37ae protein family zf-HIT PF04438.11 EKX72536.1 - 0.066 12.8 3.3 3.7 7.2 0.3 2.6 2 0 0 2 2 2 0 HIT zinc finger Lar_restr_allev PF14354.1 EKX72536.1 - 0.071 13.4 0.1 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-C2HC5 PF06221.8 EKX72536.1 - 0.074 12.8 1.2 1.9 8.3 0.2 2.3 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type DUF2296 PF10058.4 EKX72536.1 - 0.29 10.8 4.3 0.97 9.2 0.3 2.4 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-ribbon_3 PF13248.1 EKX72536.1 - 0.47 9.7 2.9 2.7 7.3 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.8 EKX72536.1 - 0.75 9.5 3.1 2.8 7.7 0.1 2.8 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like DUF1610 PF07754.6 EKX72536.1 - 1.2 9.2 5.2 2.1 8.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) CDC50 PF03381.10 EKX72537.1 - 7.6e-25 87.6 0.1 1.4e-24 86.7 0.1 1.4 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SdpI PF13630.1 EKX72537.1 - 0.8 9.4 5.8 2.1 8.1 0.3 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family RNA_pol_Rpb1_1 PF04997.7 EKX72538.1 - 3.1e-100 335.7 0.2 8e-100 334.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EKX72538.1 - 1.1e-99 333.2 0.1 3.3e-99 331.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EKX72538.1 - 4.8e-67 225.0 0.0 9.6e-67 224.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EKX72538.1 - 1.5e-45 154.7 0.0 3e-45 153.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EKX72538.1 - 3.1e-43 146.7 2.9 6.6e-43 145.6 2.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_6 PF04992.9 EKX72538.1 - 5.3e-43 146.9 0.1 9.7e-43 146.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_4 PF05000.12 EKX72538.1 - 2.2e-37 127.0 0.6 5.5e-37 125.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EKX72538.1 - 4.2e-17 60.6 221.5 0.0045 16.9 4.7 14.5 8 3 1 12 12 12 9 RNA polymerase Rpb1 C-terminal repeat Band_7 PF01145.20 EKX72539.1 - 4.4e-27 95.1 2.1 4.5e-27 95.1 0.0 1.9 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EKX72539.1 - 0.003 17.0 0.0 0.0061 16.0 0.0 1.6 1 0 0 1 1 1 1 SPFH domain-Band 7 family MHCassoc_trimer PF08831.5 EKX72541.1 - 0.0031 17.3 0.0 0.0084 15.9 0.0 1.7 1 0 0 1 1 1 1 Class II MHC-associated invariant chain trimerisation domain FAINT PF04385.10 EKX72542.1 - 5e-05 23.0 0.0 0.0017 18.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function, DUF529 BChl_A PF02327.12 EKX72543.1 - 0.1 11.2 0.2 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Bacteriochlorophyll A protein DUF498 PF04430.9 EKX72543.1 - 0.18 11.3 1.4 0.45 10.0 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) DUF4537 PF15057.1 EKX72544.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) Ribosomal_L21p PF00829.16 EKX72546.1 - 9.5e-19 67.3 0.1 1.7e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein ProRS-C_2 PF09181.5 EKX72547.1 - 0.015 15.2 0.1 0.049 13.5 0.0 1.9 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal GTP_EFTU PF00009.22 EKX72548.1 - 5.1e-36 123.8 3.5 3.2e-35 121.2 2.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.17 EKX72548.1 - 5.8e-10 38.7 2.4 2.1e-07 30.4 0.1 2.8 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EKX72548.1 - 1.6e-08 34.5 0.7 1.5e-07 31.3 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EKX72548.1 - 2.5e-08 34.4 0.4 1.3e-07 32.1 0.1 2.4 2 0 0 2 2 2 1 Miro-like protein IF-2 PF11987.3 EKX72548.1 - 2.4e-06 27.4 0.0 0.00031 20.6 0.0 3.3 3 0 0 3 3 2 1 Translation-initiation factor 2 Arf PF00025.16 EKX72548.1 - 1.8e-05 24.0 0.1 4.2e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 EKX72548.1 - 3e-05 23.3 1.0 0.0002 20.6 0.7 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EKX72548.1 - 4.1e-05 22.8 1.3 0.00022 20.5 0.9 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EKX72548.1 - 0.0012 18.3 0.7 0.0044 16.4 0.5 2.0 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EKX72548.1 - 0.0037 17.0 0.1 2.3 8.0 0.0 2.6 1 1 1 2 2 2 2 Dynamin family AAA_24 PF13479.1 EKX72548.1 - 0.064 12.8 1.8 0.63 9.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain Polysacc_deac_1 PF01522.16 EKX72548.1 - 0.068 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase Cullin_Nedd8 PF10557.4 EKX72548.1 - 2.5 7.9 5.4 3.9 7.3 0.0 3.3 4 0 0 4 4 4 0 Cullin protein neddylation domain DEAD PF00270.24 EKX72549.1 - 1.4e-40 138.5 0.1 5.1e-40 136.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKX72549.1 - 1.9e-21 75.6 0.1 1.1e-20 73.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Hydrolase_3 PF08282.7 EKX72552.1 - 1.4e-34 119.8 0.0 3.1e-34 118.7 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKX72552.1 - 0.0012 19.1 0.1 0.014 15.6 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX72552.1 - 0.0055 16.0 0.0 0.031 13.5 0.0 2.0 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase D-aminoacyl_C PF07908.7 EKX72552.1 - 0.12 11.7 0.2 0.3 10.4 0.1 1.7 1 0 0 1 1 1 0 D-aminoacylase, C-terminal region Parvo_coat PF00740.13 EKX72553.1 - 0.003 16.5 7.2 0.0038 16.2 5.0 1.0 1 0 0 1 1 1 1 Parvovirus coat protein VP2 Mitofilin PF09731.4 EKX72553.1 - 0.033 12.8 27.1 0.041 12.5 18.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Salp15 PF12115.3 EKX72553.1 - 0.068 13.3 0.0 0.98 9.6 0.0 2.7 1 1 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Aldedh PF00171.17 EKX72553.1 - 0.095 11.0 1.5 0.13 10.5 1.1 1.4 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Erythro-docking PF09277.6 EKX72553.1 - 0.1 12.3 0.0 0.46 10.2 0.0 2.2 2 0 0 2 2 2 0 Erythronolide synthase, docking Hid1 PF12722.2 EKX72553.1 - 1.3 6.6 16.2 1.6 6.3 11.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tfb4 PF03850.9 EKX72553.1 - 8.1 5.6 8.6 0.31 10.2 0.2 2.1 2 0 0 2 2 2 0 Transcription factor Tfb4 FAINT PF04385.10 EKX72554.1 - 4.1e-35 119.4 14.6 0.00013 21.7 0.0 7.7 7 0 0 7 7 7 7 Domain of unknown function, DUF529 EMA PF02488.10 EKX72554.1 - 6e-09 35.7 28.0 0.0028 17.1 0.7 6.1 6 1 1 7 7 7 4 Merozoite Antigen RNA_pol_A_bac PF01000.21 EKX72555.1 - 1.9e-08 34.4 0.0 4.6e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EKX72555.1 - 0.029 13.4 0.0 0.068 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain FAINT PF04385.10 EKX72556.1 - 0.00024 20.8 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function, DUF529 PT-TG PF14449.1 EKX72557.1 - 0.076 12.8 0.4 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 Pre-toxin TG efThoc1 PF11957.3 EKX72557.1 - 0.13 10.7 0.1 0.18 10.2 0.1 1.1 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor Suc_Fer-like PF06999.7 EKX72559.1 - 0.055 13.4 0.1 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Sucrase/ferredoxin-like FAINT PF04385.10 EKX72561.1 - 3.1e-14 52.5 1.0 3.3e-07 30.0 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72562.1 - 0.011 15.5 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function, DUF529 RRM_6 PF14259.1 EKX72563.1 - 1.4e-17 63.4 0.0 1.7e-13 50.3 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKX72563.1 - 6.5e-13 48.1 0.0 0.00013 21.5 0.0 5.0 3 2 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX72563.1 - 4e-06 26.5 0.0 0.042 13.6 0.0 4.0 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKX72563.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif DUF727 PF05303.7 EKX72563.1 - 0.13 12.0 0.0 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF727) DoxA PF07680.6 EKX72564.1 - 0.0076 15.8 0.0 0.59 9.7 0.0 2.5 2 0 0 2 2 2 2 TQO small subunit DoxA FlpD PF02662.11 EKX72565.1 - 0.04 13.6 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Archaeal_AmoA PF12942.2 EKX72568.1 - 0.067 12.9 0.1 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Archaeal ammonia monooxygenase subunit A (AmoA) FAINT PF04385.10 EKX72569.1 - 1.2e-15 57.1 4.3 5.6e-05 22.9 0.0 3.9 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX72569.1 - 1.3e-13 51.3 0.0 2.5e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX72569.1 - 2.6e-09 36.8 0.0 1.2e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EKX72569.1 - 7.3e-09 35.5 0.0 1.7e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EKX72569.1 - 0.05 13.0 0.0 7.1 6.0 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EKX72569.1 - 0.084 12.4 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAINT PF04385.10 EKX72570.1 - 2.8e-12 46.2 4.6 8.5e-06 25.5 1.5 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72570.1 - 5.8e-05 22.6 0.2 0.00026 20.5 0.1 1.9 2 0 0 2 2 2 1 Merozoite Antigen zf-NPL4 PF05020.10 EKX72571.1 - 0.00066 19.3 0.3 0.0013 18.4 0.2 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region Syndecan PF01034.15 EKX72571.1 - 0.0036 16.9 0.7 0.008 15.8 0.5 1.5 1 0 0 1 1 1 1 Syndecan domain DNA_pol_B PF00136.16 EKX72572.1 - 3.8e-97 325.9 0.0 6.5e-97 325.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B FAINT PF04385.10 EKX72572.1 - 7.5e-17 60.9 10.5 1.7e-05 24.5 0.2 4.8 5 0 0 5 5 5 3 Domain of unknown function, DUF529 DNA_pol_B_exo1 PF03104.14 EKX72573.1 - 4.2e-25 88.3 1.0 5.7e-25 87.8 0.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EKX72573.1 - 2.5e-13 49.6 10.2 4.9e-13 48.6 7.1 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal WD40 PF00400.27 EKX72574.1 - 4.2e-15 54.9 6.7 6.9e-05 22.5 0.3 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EKX72574.1 - 0.00026 20.4 0.0 0.0027 17.1 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 EKX72574.1 - 0.0034 17.1 5.4 15 5.2 0.0 5.6 7 0 0 7 7 7 2 Transcription factor IIIC subunit delta N-term WD40 PF00400.27 EKX72575.1 - 2e-14 52.8 0.3 3e-10 39.5 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat OTOS PF15182.1 EKX72576.1 - 0.028 14.0 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 Otospiralin DRP PF06044.7 EKX72578.1 - 0.019 13.9 0.3 0.035 13.0 0.2 1.3 1 0 0 1 1 1 0 Dam-replacing family Thioredoxin PF00085.15 EKX72579.1 - 1.4e-05 24.6 0.0 4.2e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 EKX72579.1 - 0.049 13.6 0.0 6.9 6.7 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin-like YlbD_coat PF14071.1 EKX72579.1 - 0.23 11.5 2.5 9.4 6.3 0.0 2.9 2 1 0 2 2 2 0 Putative coat protein NTP_transf_2 PF01909.18 EKX72580.1 - 7.5e-05 22.9 0.0 0.00018 21.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EKX72580.1 - 0.0044 16.9 0.8 0.02 14.8 0.0 2.4 2 0 0 2 2 2 1 Cid1 family poly A polymerase Cpn60_TCP1 PF00118.19 EKX72581.1 - 5.6e-101 338.5 4.8 7.1e-101 338.2 3.3 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF572 PF04502.8 EKX72583.1 - 2e-38 132.4 15.4 2e-37 129.1 10.7 2.2 1 1 0 1 1 1 1 Family of unknown function (DUF572) ATP-synt_10 PF05176.9 EKX72584.1 - 0.019 14.2 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 ATP10 protein FAINT PF04385.10 EKX72586.1 - 3.5e-15 55.6 18.3 4.5e-06 26.4 0.2 5.4 5 0 0 5 5 5 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX72586.1 - 1.1e-10 41.7 0.0 1.9e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX72586.1 - 2e-07 30.8 0.0 4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX72586.1 - 6.9e-07 29.0 0.1 2.1e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 Putative lysophospholipase SIS_2 PF13580.1 EKX72586.1 - 0.0096 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 SIS domain Abhydrolase_3 PF07859.8 EKX72586.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAINT PF04385.10 EKX72588.1 - 1.5e-40 136.8 7.0 2.1e-10 40.2 0.1 5.5 5 0 0 5 5 5 5 Domain of unknown function, DUF529 EMA PF02488.10 EKX72588.1 - 0.001 18.6 1.0 0.12 11.7 0.0 3.2 3 0 0 3 3 3 1 Merozoite Antigen FAINT PF04385.10 EKX72589.1 - 1.5e-43 146.5 11.1 7e-08 32.2 0.0 7.8 7 0 0 7 7 7 7 Domain of unknown function, DUF529 Glyoxalase_5 PF14696.1 EKX72592.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal FAINT PF04385.10 EKX72593.1 - 3e-06 26.9 0.1 4.9e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Chibby PF14645.1 EKX72593.1 - 0.024 14.4 0.2 0.046 13.6 0.1 1.5 2 0 0 2 2 2 0 Chibby family FAINT PF04385.10 EKX72594.1 - 5.4e-07 29.3 0.1 1e-06 28.4 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function, DUF529 Cpn60_TCP1 PF00118.19 EKX72595.1 - 6.6e-143 476.8 8.1 7.6e-143 476.6 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Adeno_52K PF03052.10 EKX72596.1 - 0.0057 15.9 0.0 0.0084 15.3 0.0 1.2 1 0 0 1 1 1 1 Adenoviral protein L1 52/55-kDa ESSS PF10183.4 EKX72596.1 - 2.1 8.7 3.6 6.6 7.1 0.0 3.1 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3311 PF11755.3 EKX72596.1 - 2.7 7.5 11.1 0.23 11.0 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) SF3b1 PF08920.5 EKX72597.1 - 1.1e-29 103.3 1.3 6e-24 84.7 0.0 2.6 2 0 0 2 2 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EKX72597.1 - 1.4e-14 54.1 8.0 0.0013 18.9 0.0 7.4 4 2 3 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 EKX72597.1 - 3.8e-09 36.7 8.8 0.087 13.3 0.0 7.8 9 1 1 10 10 10 3 HEAT-like repeat HEAT PF02985.17 EKX72597.1 - 6e-07 29.0 9.7 0.024 14.6 0.0 8.2 10 0 0 10 10 10 2 HEAT repeat CLASP_N PF12348.3 EKX72597.1 - 0.0011 18.4 0.3 2.3 7.5 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 EKX72597.1 - 0.01 16.1 0.0 0.3 11.4 0.0 3.0 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Arm PF00514.18 EKX72597.1 - 0.032 14.0 5.7 6.4 6.7 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.5 EKX72597.1 - 0.056 13.0 0.0 0.45 10.0 0.0 2.5 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) DNA_methylase PF00145.12 EKX72598.1 - 2.7e-13 49.7 0.7 8.1e-07 28.4 0.0 4.8 3 1 0 3 3 3 3 C-5 cytosine-specific DNA methylase DUF4602 PF15375.1 EKX72598.1 - 0.05 13.6 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) Cons_hypoth95 PF03602.10 EKX72598.1 - 0.12 11.7 0.0 26 4.1 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical protein 95 MethyltransfD12 PF02086.10 EKX72598.1 - 0.15 11.4 0.9 0.3 10.5 0.0 1.9 2 1 1 3 3 3 0 D12 class N6 adenine-specific DNA methyltransferase FluMu_gp41 PF10109.4 EKX72599.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Mu-like prophage FluMu protein gp41 Matrilin_ccoil PF10393.4 EKX72600.1 - 0.067 12.5 0.0 0.2 11.0 0.0 1.8 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Prp19 PF08606.6 EKX72601.1 - 7e-31 105.7 0.8 1.4e-30 104.8 0.5 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EKX72601.1 - 3.1e-26 90.2 14.6 2.1e-05 24.1 0.2 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat U-box PF04564.10 EKX72601.1 - 1.5e-05 24.8 0.0 3.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 U-box domain DUF3312 PF11768.3 EKX72601.1 - 0.0047 15.2 0.0 4.8 5.2 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF3312) FAINT PF04385.10 EKX72602.1 - 5.6e-11 42.1 1.3 1.2e-05 25.0 0.0 3.1 2 1 0 2 2 2 2 Domain of unknown function, DUF529 Carbpep_Y_N PF05388.6 EKX72602.1 - 0.054 13.6 0.0 7.8 6.6 0.0 2.3 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide Hydrolase_3 PF08282.7 EKX72603.1 - 5.9e-32 111.2 0.0 7.5e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX72603.1 - 8e-05 22.0 0.0 0.22 10.7 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EKX72603.1 - 0.0084 16.2 0.1 0.018 15.1 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAINT PF04385.10 EKX72604.1 - 0.00019 21.1 3.7 0.0019 18.0 0.0 3.2 4 0 0 4 4 4 2 Domain of unknown function, DUF529 Elf1 PF05129.8 EKX72605.1 - 0.07 12.8 0.5 0.18 11.5 0.3 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DUF2273 PF10031.4 EKX72605.1 - 0.3 10.7 3.4 0.65 9.6 2.3 1.5 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) DEAD PF00270.24 EKX72606.1 - 2.1e-31 108.6 1.1 3.7e-31 107.8 0.3 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKX72606.1 - 1e-21 76.5 0.0 2.8e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKX72606.1 - 3.3e-05 23.7 0.0 7.7e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EKX72606.1 - 0.00021 19.8 0.2 0.0046 15.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 EKX72606.1 - 0.0075 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_22 PF13401.1 EKX72606.1 - 0.0089 16.1 1.3 0.043 13.9 0.4 2.4 2 1 0 2 2 2 1 AAA domain T4SS-DNA_transf PF02534.9 EKX72606.1 - 0.016 13.8 0.0 0.032 12.8 0.0 1.5 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer CobA_CobO_BtuR PF02572.10 EKX72606.1 - 0.085 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP IMPDH PF00478.20 EKX72607.1 - 1.1e-127 425.7 1.6 1.4e-127 425.4 1.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EKX72607.1 - 7.4e-12 45.0 5.8 1.7e-06 27.4 1.7 2.8 3 1 1 4 4 4 2 Nitronate monooxygenase FMN_dh PF01070.13 EKX72607.1 - 9.3e-09 34.5 0.6 1.3e-07 30.7 0.5 2.6 2 1 0 2 2 2 1 FMN-dependent dehydrogenase CBS PF00571.23 EKX72607.1 - 4.1e-08 32.8 0.3 0.0091 15.7 0.0 2.8 2 1 0 2 2 2 2 CBS domain His_biosynth PF00977.16 EKX72607.1 - 0.0024 17.1 0.6 0.022 14.0 0.4 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein Response_reg PF00072.19 EKX72607.1 - 0.0026 17.7 0.1 0.058 13.3 0.0 2.9 4 0 0 4 4 4 1 Response regulator receiver domain Glu_synthase PF01645.12 EKX72607.1 - 0.0036 16.2 1.7 0.0081 15.1 1.1 1.6 1 1 1 2 2 2 1 Conserved region in glutamate synthase DHO_dh PF01180.16 EKX72607.1 - 0.017 14.1 3.2 0.037 12.9 0.5 2.2 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase B12-binding PF02310.14 EKX72607.1 - 0.027 14.3 0.1 0.089 12.6 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain ThiG PF05690.9 EKX72607.1 - 0.04 13.0 1.2 0.094 11.7 0.5 1.8 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG PcrB PF01884.12 EKX72607.1 - 0.074 12.2 5.8 1.9 7.6 0.1 4.0 4 1 1 5 5 5 0 PcrB family FAINT PF04385.10 EKX72608.1 - 2e-19 69.2 13.6 4.6e-06 26.3 0.6 4.9 4 0 0 4 4 4 4 Domain of unknown function, DUF529 EMA PF02488.10 EKX72611.1 - 2.2e-05 24.0 0.3 3e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 EKX72615.1 - 3.4e-25 87.6 8.8 5.7e-08 32.4 0.1 4.9 5 0 0 5 5 5 4 Domain of unknown function, DUF529 CRAL_TRIO PF00650.15 EKX72617.1 - 1.1e-31 109.5 0.0 1.7e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EKX72617.1 - 7.8e-08 32.3 0.1 2.5e-07 30.7 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain FAINT PF04385.10 EKX72618.1 - 1.8e-25 88.5 8.6 1.4e-06 28.0 0.1 7.0 6 1 1 7 7 7 6 Domain of unknown function, DUF529 Rhodanese PF00581.15 EKX72618.1 - 0.032 14.5 0.1 0.09 13.1 0.1 1.8 1 0 0 1 1 1 0 Rhodanese-like domain FAINT PF04385.10 EKX72621.1 - 9.8e-07 28.5 0.1 2.2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function, DUF529 EMA PF02488.10 EKX72621.1 - 0.00023 20.7 1.1 0.00027 20.4 0.8 1.1 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 EKX72622.1 - 5.8e-15 54.8 0.0 2.1e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72622.1 - 0.00011 21.7 0.1 0.0042 16.5 0.2 2.0 2 0 0 2 2 2 1 Merozoite Antigen DUF1381 PF07129.6 EKX72622.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) CBM_25 PF03423.8 EKX72622.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) zf-DHHC PF01529.15 EKX72623.1 - 3.8e-30 104.5 9.5 3.8e-30 104.5 6.6 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase IncA PF04156.9 EKX72623.1 - 0.058 12.9 0.2 0.058 12.9 0.1 2.0 2 0 0 2 2 2 0 IncA protein Pex24p PF06398.6 EKX72623.1 - 0.36 9.5 0.0 0.36 9.5 0.0 2.3 2 1 1 3 3 3 0 Integral peroxisomal membrane peroxin DUF2207 PF09972.4 EKX72623.1 - 0.68 8.4 5.5 0.29 9.6 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.1 EKX72623.1 - 0.88 8.9 0.0 0.88 8.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.20 EKX72624.1 - 7.8e-67 225.1 0.0 2.9e-66 223.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.24 EKX72624.1 - 8.3e-63 208.2 2.9 1.3e-18 66.5 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 EKX72624.1 - 1.1e-32 113.1 0.0 3.6e-32 111.4 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 EKX72624.1 - 3.6e-06 26.1 0.0 6.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Cupin_2 PF07883.6 EKX72624.1 - 7.1e-05 22.2 5.1 0.4 10.2 0.1 4.3 4 0 0 4 4 4 2 Cupin domain Kdo PF06293.9 EKX72624.1 - 0.0088 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKX72624.1 - 0.01 15.5 0.0 0.027 14.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EKX72624.1 - 0.042 13.1 0.1 1.7 7.9 0.0 2.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Metallophos PF00149.23 EKX72625.1 - 0.00032 20.1 0.2 0.00092 18.6 0.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKX72625.1 - 0.01 15.7 0.0 0.07 12.9 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Zip PF02535.17 EKX72626.1 - 1.9e-18 66.5 8.2 2.2e-18 66.3 5.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Ribosomal_L3 PF00297.17 EKX72627.1 - 1.5e-26 93.3 1.0 6.6e-26 91.2 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L3 RRM_1 PF00076.17 EKX72628.1 - 4e-32 109.6 1.1 1.6e-15 56.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX72628.1 - 6.9e-28 96.4 0.1 6.8e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX72628.1 - 4.5e-11 42.4 0.1 5.3e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKX72628.1 - 6.9e-05 22.5 0.1 0.083 12.6 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 EKX72628.1 - 0.022 14.2 0.1 4.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain Peptidase_C25 PF01364.13 EKX72628.1 - 0.044 12.7 1.6 1.7 7.5 0.2 2.2 2 0 0 2 2 2 0 Peptidase family C25 Mitofilin PF09731.4 EKX72628.1 - 6.8 5.2 13.6 8.3 4.9 9.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LSM PF01423.17 EKX72629.1 - 2.4e-14 52.5 0.0 3.3e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EKX72629.1 - 0.00092 19.0 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain RAP PF08373.5 EKX72630.1 - 0.001 18.8 1.0 0.0022 17.7 0.0 2.1 2 0 0 2 2 2 1 RAP domain Telomerase_RBD PF12009.3 EKX72633.1 - 3.3e-27 95.0 9.6 2.3e-26 92.2 4.4 2.7 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EKX72633.1 - 1.2e-12 47.6 0.0 2.2e-11 43.5 0.0 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Macro PF01661.16 EKX72634.1 - 6.4e-06 26.0 0.0 3e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Macro domain FYVE PF01363.16 EKX72636.1 - 3.1e-06 26.9 7.2 5.8e-06 26.1 5.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 EKX72636.1 - 0.034 14.0 4.5 0.26 11.2 0.3 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger ParB PF08775.5 EKX72636.1 - 0.046 14.0 2.4 0.15 12.3 0.7 2.3 2 1 0 2 2 2 0 ParB family C1_1 PF00130.17 EKX72636.1 - 0.098 12.3 9.5 0.82 9.4 0.6 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UPF0547 PF10571.4 EKX72636.1 - 0.56 9.9 0.1 0.56 9.9 0.1 3.0 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 IBR PF01485.16 EKX72636.1 - 2.3 8.1 9.4 0.084 12.7 2.1 1.9 2 0 0 2 2 2 0 IBR domain Sdh5 PF03937.11 EKX72638.1 - 0.0062 16.1 0.1 0.01 15.5 0.1 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase AP2 PF00847.15 EKX72639.1 - 1.5e-34 117.8 13.9 2.2e-11 43.7 0.2 3.4 3 0 0 3 3 3 3 AP2 domain DUF2389 PF09493.5 EKX72639.1 - 0.0026 18.0 0.1 7.2 6.9 0.0 3.2 3 0 0 3 3 3 2 Tryptophan-rich protein (DUF2389) Rubredoxin PF00301.15 EKX72640.1 - 6.6e-06 25.9 2.0 2.6e-05 23.9 1.4 2.0 1 1 0 1 1 1 1 Rubredoxin Zn_Tnp_IS1595 PF12760.2 EKX72640.1 - 0.0048 16.6 0.4 1.7 8.5 0.0 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Auto_anti-p27 PF06677.7 EKX72640.1 - 0.0053 16.4 0.6 2.3 8.0 0.0 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.1 EKX72640.1 - 0.0093 15.1 2.2 0.041 13.1 0.3 2.4 2 0 0 2 2 2 1 zinc-ribbon domain zf-Mss51 PF13824.1 EKX72640.1 - 0.0094 15.7 1.8 0.66 9.8 0.1 2.4 1 1 1 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF1610 PF07754.6 EKX72640.1 - 0.013 15.5 5.4 0.026 14.6 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zinc_ribbon_2 PF13240.1 EKX72640.1 - 0.022 14.2 2.5 0.2 11.1 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.1 EKX72640.1 - 0.03 14.0 0.5 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Nudix N-terminal zf-HIT PF04438.11 EKX72640.1 - 0.031 13.9 1.7 1.8 8.3 0.1 2.8 2 0 0 2 2 2 0 HIT zinc finger DUF164 PF02591.10 EKX72640.1 - 0.036 13.8 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 Putative zinc ribbon domain TF_Zn_Ribbon PF08271.7 EKX72640.1 - 0.072 12.4 1.6 0.69 9.2 0.2 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding DUF35_N PF12172.3 EKX72640.1 - 0.074 12.9 2.8 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2296 PF10058.4 EKX72640.1 - 0.11 12.2 2.4 5.7 6.7 0.1 2.7 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) HypA PF01155.14 EKX72640.1 - 0.15 11.7 0.2 0.27 10.9 0.1 1.6 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family TFIIS_C PF01096.13 EKX72640.1 - 0.32 10.6 2.5 3.5 7.3 0.2 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) GFA PF04828.9 EKX72640.1 - 0.7 9.8 3.6 1.8 8.5 0.1 2.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn-ribbon_8 PF09723.5 EKX72640.1 - 1 9.3 4.2 7.6 6.5 2.9 2.3 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2 PF00096.21 EKX72640.1 - 1.3 9.5 3.6 31 5.1 0.3 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Elf1 PF05129.8 EKX72640.1 - 2.3 7.9 7.4 1.9 8.2 0.4 2.8 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Ribonuc_red_lgC PF02867.10 EKX72641.1 - 2.3e-216 719.5 0.0 3.2e-216 719.0 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EKX72641.1 - 1.5e-22 79.1 0.3 9.2e-22 76.6 0.0 2.4 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EKX72641.1 - 3.2e-11 43.4 0.0 1.1e-10 41.7 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 EKX72641.1 - 0.00012 20.3 0.0 0.00019 19.6 0.0 1.2 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase CLP_protease PF00574.18 EKX72643.1 - 2.1e-36 125.2 0.0 5.9e-36 123.8 0.0 1.6 1 1 0 1 1 1 1 Clp protease OpcA PF07239.6 EKX72643.1 - 0.0011 17.8 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein OpcA DUF1296 PF06972.6 EKX72643.1 - 0.044 13.7 0.1 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) IF2_N PF04760.10 EKX72643.1 - 0.088 12.4 0.4 0.088 12.4 0.3 2.0 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region HIT PF01230.18 EKX72644.1 - 1.2e-19 70.6 0.1 2.7e-19 69.5 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EKX72644.1 - 1.4e-08 34.9 0.0 2.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MFS_1 PF07690.11 EKX72645.1 - 6.1e-17 61.3 16.6 6.1e-17 61.3 11.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2484 PF10658.4 EKX72645.1 - 0.19 11.8 0.2 0.19 11.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2484) PgaD PF13994.1 EKX72645.1 - 3.2 7.2 5.3 1.3 8.5 0.0 2.8 4 0 0 4 4 4 0 PgaD-like protein Sld5 PF05916.6 EKX72646.1 - 2.6e-08 34.0 0.0 4.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein UQ_con PF00179.21 EKX72647.1 - 5.9e-43 145.6 0.0 6.7e-43 145.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKX72647.1 - 0.00088 19.0 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EKX72647.1 - 0.032 14.1 0.2 0.064 13.1 0.2 1.8 1 1 0 1 1 1 0 RWD domain Pyr_redox_2 PF07992.9 EKX72648.1 - 1.2e-17 64.4 0.0 3.8e-17 62.8 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKX72648.1 - 9.5e-09 35.5 0.0 2.8e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKX72648.1 - 0.081 12.9 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.2 EKX72649.1 - 5e-23 81.2 0.6 1.5e-20 73.2 0.2 3.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 EKX72649.1 - 7.2e-21 72.8 2.4 1.1e-06 28.1 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EKX72649.1 - 3.7e-19 66.8 1.1 0.0004 20.3 0.0 5.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EKX72649.1 - 4.1e-16 59.0 4.1 2.5e-11 43.7 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKX72649.1 - 6.5e-12 45.2 1.3 4e-07 30.0 0.1 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) TPR_16 PF13432.1 EKX72649.1 - 0.0025 18.4 0.0 0.051 14.2 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKX72649.1 - 0.078 13.3 0.2 0.48 10.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2183 PF09949.4 EKX72650.1 - 6.2e-06 26.0 0.0 1.6e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) TPT PF03151.11 EKX72651.1 - 3.3e-29 101.5 25.2 2.9e-27 95.2 6.5 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EKX72651.1 - 2.1e-07 31.0 28.5 2e-06 27.8 8.8 2.8 2 2 1 3 3 3 2 EamA-like transporter family UAA PF08449.6 EKX72651.1 - 0.0047 15.8 17.2 0.088 11.7 11.9 2.4 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EKX72651.1 - 0.013 14.6 9.2 0.029 13.4 0.4 2.7 1 1 1 3 3 3 0 Nucleotide-sugar transporter RCC1 PF00415.13 EKX72652.1 - 1e-112 368.2 46.4 2.9e-13 49.7 0.2 15.0 15 2 0 15 15 15 13 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EKX72652.1 - 1.3e-49 164.8 90.1 4.2e-07 29.3 0.7 14.0 14 2 0 14 14 14 10 Regulator of chromosome condensation (RCC1) repeat Stk19 PF10494.4 EKX72652.1 - 0.021 14.2 0.2 0.053 12.9 0.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 RasGAP_C PF03836.10 EKX72652.1 - 0.17 11.5 2.8 0.35 10.5 0.8 2.3 2 0 0 2 2 2 0 RasGAP C-terminus DUF4213 PF13938.1 EKX72652.1 - 0.25 11.4 1.5 7.8 6.7 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4213) DEAD PF00270.24 EKX72653.1 - 4.4e-45 153.2 0.0 1.8e-44 151.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKX72653.1 - 1.1e-24 86.1 0.1 5.7e-24 83.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EKX72653.1 - 8.6e-05 21.4 0.0 0.00016 20.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1777 PF08648.7 EKX72653.1 - 8 6.1 43.4 5.1 6.8 27.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) DEAD PF00270.24 EKX72655.1 - 3.2e-49 166.6 0.0 4.1e-48 163.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKX72655.1 - 2e-27 94.8 0.1 6.4e-27 93.2 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EKX72655.1 - 3.4e-05 22.4 0.0 0.00029 19.3 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1253) ResIII PF04851.10 EKX72655.1 - 0.024 14.4 0.0 0.073 12.8 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit HAD PF12710.2 EKX72656.1 - 2.4e-13 50.6 2.0 7.3e-13 49.1 1.4 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EKX72656.1 - 1.7e-12 46.8 0.0 1.7e-12 46.8 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EKX72656.1 - 7e-11 42.9 0.0 2.5e-09 37.8 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EKX72656.1 - 0.012 15.1 0.4 0.056 13.0 0.0 2.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKX72656.1 - 0.024 14.5 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF4191 PF13829.1 EKX72656.1 - 5.7 5.9 10.1 1 8.4 1.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Claudin_2 PF13903.1 EKX72657.1 - 0.028 14.1 2.0 0.49 10.0 0.2 2.9 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Hydrolase_3 PF08282.7 EKX72658.1 - 7.6e-41 140.3 0.0 1e-40 139.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKX72658.1 - 1.1e-05 25.6 0.0 0.00024 21.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX72658.1 - 0.00017 20.9 0.0 0.089 12.0 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EKX72658.1 - 0.023 15.0 0.0 0.87 9.9 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase POTRA_1 PF08478.5 EKX72658.1 - 0.053 13.5 0.0 1.2 9.2 0.0 2.8 3 0 0 3 3 3 0 POTRA domain, FtsQ-type FAINT PF04385.10 EKX72659.1 - 0.0026 17.5 1.0 0.99 9.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Clathrin PF00637.15 EKX72660.1 - 1.8e-139 458.8 42.7 5.4e-27 94.1 0.2 8.4 8 0 0 8 8 8 8 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EKX72660.1 - 4.7e-23 80.8 0.6 4.2e-22 77.8 0.0 2.8 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 EKX72660.1 - 1e-05 25.4 0.3 1.6 9.2 0.0 4.7 4 0 0 4 4 4 2 Clathrin propeller repeat TPR_12 PF13424.1 EKX72660.1 - 0.00016 21.5 8.1 1.5 8.7 0.6 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EKX72660.1 - 0.076 12.9 0.1 0.076 12.9 0.0 7.2 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 EKX72660.1 - 0.08 12.7 12.7 0.17 11.7 0.2 5.8 5 2 1 6 6 6 0 Tetratricopeptide repeat Ssl1 PF04056.9 EKX72661.1 - 6.6e-54 182.4 0.0 8.9e-54 182.0 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 EKX72661.1 - 2.5e-12 47.2 0.0 3.1e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.7 EKX72661.1 - 1.1e-05 25.3 14.8 1.1e-05 25.3 10.3 2.8 2 1 0 2 2 2 1 TFIIH C1-like domain Tfb4 PF03850.9 EKX72661.1 - 0.00032 20.0 0.2 0.00032 20.0 0.1 1.7 2 0 0 2 2 2 1 Transcription factor Tfb4 VWA PF00092.23 EKX72661.1 - 0.0007 19.3 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-U1 PF06220.7 EKX72661.1 - 0.031 13.8 4.3 0.11 12.1 3.0 1.9 1 0 0 1 1 1 0 U1 zinc finger DZR PF12773.2 EKX72661.1 - 2.7 7.9 30.1 6 6.7 6.3 3.4 2 1 1 3 3 3 0 Double zinc ribbon UBN2 PF14223.1 EKX72662.1 - 0.15 11.8 7.2 0.03 14.1 1.9 2.2 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type DUF981 PF06168.6 EKX72664.1 - 0.11 12.2 4.6 0.19 11.4 2.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF981) Ribosomal_L34e PF01199.13 EKX72667.1 - 1.4e-35 121.4 6.9 1.4e-35 121.4 4.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L34e Wound_ind PF08186.6 EKX72667.1 - 0.83 9.6 5.3 0.19 11.6 0.5 2.2 1 1 1 2 2 2 0 Wound-inducible basic protein family tRNA-synt_2 PF00152.15 EKX72668.1 - 1.5e-79 267.1 0.0 1.9e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EKX72668.1 - 4.8e-09 35.9 0.0 8.1e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EKX72668.1 - 2.5e-05 23.6 0.1 0.22 10.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) AAA PF00004.24 EKX72669.1 - 7.8e-91 301.1 0.0 4e-45 153.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EKX72669.1 - 5.7e-15 54.9 0.0 2.7e-06 26.6 0.0 3.2 3 2 1 4 4 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EKX72669.1 - 6e-14 52.3 0.0 3.3e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EKX72669.1 - 3.5e-12 47.2 0.0 6.5e-05 23.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EKX72669.1 - 3.8e-12 46.5 0.1 0.0002 21.4 0.0 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EKX72669.1 - 7.3e-12 45.5 0.4 0.003 17.6 0.0 4.3 2 2 1 3 3 3 3 AAA domain AAA_5 PF07728.9 EKX72669.1 - 1.2e-11 44.5 0.1 7e-05 22.5 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EKX72669.1 - 4.6e-11 42.7 0.0 0.00024 20.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EKX72669.1 - 2.7e-10 39.6 0.0 9.9e-05 21.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 EKX72669.1 - 4.4e-10 39.6 0.0 0.00014 21.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EKX72669.1 - 8.5e-10 37.8 0.0 0.00024 19.9 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EKX72669.1 - 4.5e-08 32.7 0.4 0.004 16.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EKX72669.1 - 5.9e-08 32.3 4.2 0.0025 17.5 0.8 3.2 3 0 0 3 3 3 2 Part of AAA domain CDC48_N PF02359.13 EKX72669.1 - 7.5e-08 32.2 0.4 1.9e-07 30.8 0.3 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_18 PF13238.1 EKX72669.1 - 1.9e-07 31.4 0.0 0.016 15.5 0.0 3.3 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 EKX72669.1 - 3.6e-07 30.3 0.0 0.012 15.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 EKX72669.1 - 5.3e-07 29.4 0.1 0.23 11.0 0.0 3.7 3 1 0 4 4 4 2 NACHT domain Mg_chelatase PF01078.16 EKX72669.1 - 1.1e-06 27.9 0.9 0.027 13.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EKX72669.1 - 1.2e-06 28.9 0.1 0.072 13.3 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_28 PF13521.1 EKX72669.1 - 1.5e-06 28.2 0.0 0.033 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EKX72669.1 - 1.5e-06 27.7 2.7 0.24 10.8 0.0 4.0 3 1 1 4 4 4 2 AAA domain Viral_helicase1 PF01443.13 EKX72669.1 - 1.6e-06 27.8 0.0 0.0032 17.0 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.1 EKX72669.1 - 3.7e-06 27.0 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 EKX72669.1 - 2.5e-05 23.8 0.0 0.1 12.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EKX72669.1 - 3.8e-05 23.5 0.0 0.5 10.0 0.0 3.6 2 2 1 3 3 3 2 Archaeal ATPase Parvo_NS1 PF01057.12 EKX72669.1 - 5.1e-05 22.2 0.2 0.026 13.3 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 PhoH PF02562.11 EKX72669.1 - 5.9e-05 22.3 0.2 0.17 11.1 0.1 2.5 2 1 0 2 2 2 2 PhoH-like protein Vps4_C PF09336.5 EKX72669.1 - 8.1e-05 22.4 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.21 EKX72669.1 - 0.00013 21.4 0.1 1.3 8.4 0.0 3.7 3 1 0 3 3 2 2 Sigma-54 interaction domain NB-ARC PF00931.17 EKX72669.1 - 0.00021 20.2 0.1 0.24 10.2 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Bac_DnaA PF00308.13 EKX72669.1 - 0.00023 20.8 0.0 0.91 9.1 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein UPF0079 PF02367.12 EKX72669.1 - 0.00072 19.1 0.1 0.59 9.7 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Molydop_binding PF01568.16 EKX72669.1 - 0.00073 19.3 0.0 0.0031 17.3 0.0 1.9 2 0 0 2 2 1 1 Molydopterin dinucleotide binding domain NTPase_1 PF03266.10 EKX72669.1 - 0.00094 18.9 0.4 4.1 7.0 0.0 4.1 3 1 1 4 4 3 0 NTPase KaiC PF06745.8 EKX72669.1 - 0.0011 18.1 0.1 2.7 7.0 0.0 3.1 2 1 1 3 3 3 1 KaiC DUF2075 PF09848.4 EKX72669.1 - 0.0015 17.5 0.0 0.58 9.0 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.1 EKX72669.1 - 0.002 18.0 0.2 0.56 10.0 0.0 2.9 2 1 1 3 3 3 1 Cytidylate kinase-like family AAA_23 PF13476.1 EKX72669.1 - 0.0029 17.9 0.8 3.6 7.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain ResIII PF04851.10 EKX72669.1 - 0.0053 16.6 0.0 4.1 7.2 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EKX72669.1 - 0.0054 16.3 0.1 0.35 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EKX72669.1 - 0.0054 16.3 0.0 2.6 7.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain SKI PF01202.17 EKX72669.1 - 0.0094 15.8 0.0 2.3 8.0 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase DUF815 PF05673.8 EKX72669.1 - 0.011 14.7 0.0 0.43 9.4 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EKX72669.1 - 0.015 14.8 0.0 1.5 8.2 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain KTI12 PF08433.5 EKX72669.1 - 0.016 14.4 0.0 1.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 T2SE PF00437.15 EKX72669.1 - 0.018 13.9 0.0 4.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 EKX72669.1 - 0.022 14.3 0.0 6.8 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EKX72669.1 - 0.034 13.1 0.5 3 6.7 0.0 2.9 3 1 0 3 3 2 0 KAP family P-loop domain Zot PF05707.7 EKX72669.1 - 0.035 13.5 0.3 3.6 7.0 0.0 3.6 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) cobW PF02492.14 EKX72669.1 - 0.037 13.4 0.1 3.2 7.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CPT PF07931.7 EKX72669.1 - 0.069 12.7 0.0 2.9 7.4 0.0 2.7 2 1 1 3 3 2 0 Chloramphenicol phosphotransferase-like protein AAA_10 PF12846.2 EKX72669.1 - 0.077 12.4 0.1 5 6.4 0.0 3.0 3 1 0 3 3 2 0 AAA-like domain DAP3 PF10236.4 EKX72669.1 - 0.099 11.5 0.0 11 4.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Glyco_trans_1_4 PF13692.1 EKX72670.1 - 1.4e-09 38.1 0.0 3.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EKX72670.1 - 2.9e-07 30.0 0.0 6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DNA_mis_repair PF01119.14 EKX72671.1 - 4.3e-24 84.2 0.1 9.2e-24 83.1 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EKX72671.1 - 1.6e-16 60.1 0.0 7.4e-16 58.0 0.0 2.1 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EKX72671.1 - 6.8e-13 48.4 0.4 1.5e-12 47.2 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EKX72671.1 - 8.2e-10 38.3 0.1 2.2e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UCH PF00443.24 EKX72673.1 - 7.7e-46 156.3 4.3 7.7e-46 156.3 3.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKX72673.1 - 1.9e-18 66.9 0.1 5.1e-10 39.2 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EKX72673.1 - 5.4e-11 42.3 0.9 9.5e-10 38.2 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal Ribosomal_S21 PF01165.15 EKX72674.1 - 0.25 10.8 5.0 0.12 11.8 1.0 2.3 2 1 0 2 2 2 0 Ribosomal protein S21 Nol1_Nop2_Fmu PF01189.12 EKX72675.1 - 9.4e-17 61.2 0.0 2.9e-16 59.7 0.0 1.8 2 1 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EKX72675.1 - 9.8e-08 31.7 0.1 6.6e-07 29.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKX72675.1 - 5.8e-05 23.3 0.0 0.00026 21.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKX72675.1 - 9.9e-05 22.3 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKX72675.1 - 0.00026 21.5 0.0 0.00083 19.9 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EKX72675.1 - 0.0097 15.9 0.0 0.024 14.6 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.7 EKX72675.1 - 0.065 13.7 0.0 2.1 8.8 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain POR PF01558.13 EKX72675.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Methyltransf_23 PF13489.1 EKX72675.1 - 0.15 11.8 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Vps51 PF08700.6 EKX72676.1 - 2.1e-14 53.1 0.5 7.6e-14 51.3 0.4 2.1 1 0 0 1 1 1 1 Vps51/Vps67 DUF605 PF04652.11 EKX72677.1 - 4.4e-19 69.1 4.5 9.1e-10 38.4 0.5 3.0 1 1 1 2 2 2 2 Vta1 like Hist_deacetyl PF00850.14 EKX72679.1 - 2.1e-71 240.7 0.0 5e-71 239.5 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain Ank_4 PF13637.1 EKX72679.1 - 4.3e-11 43.0 0.2 0.00013 22.4 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKX72679.1 - 0.00011 22.4 0.0 0.37 11.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKX72679.1 - 0.00048 20.2 0.0 0.25 11.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKX72679.1 - 0.0062 16.6 0.1 2.1 8.8 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat GpcrRhopsn4 PF10192.4 EKX72680.1 - 0.00011 21.4 13.4 0.00011 21.4 9.3 1.7 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.8 EKX72680.1 - 0.059 12.3 18.9 0.086 11.7 13.1 1.2 1 0 0 1 1 1 0 Lung seven transmembrane receptor HSP20 PF00011.16 EKX72681.1 - 5e-10 39.1 0.2 7.6e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PIH1 PF08190.7 EKX72681.1 - 0.049 13.0 0.1 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Beta-Casp PF10996.3 EKX72682.1 - 4.7e-31 107.3 0.0 1.1e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain CPSF73-100_C PF11718.3 EKX72682.1 - 1.1e-26 93.5 6.6 1.7e-26 92.9 4.6 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B PF00753.22 EKX72682.1 - 5.3e-13 49.0 0.1 2e-12 47.1 0.1 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EKX72682.1 - 4.6e-12 45.5 0.0 1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EKX72682.1 - 1.2e-09 38.0 0.3 4.1e-09 36.2 0.3 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EKX72682.1 - 0.014 15.0 0.0 0.046 13.4 0.0 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF410 PF04190.8 EKX72683.1 - 4.9e-16 59.0 0.1 1.1e-15 57.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF410) RseC_MucC PF04246.7 EKX72684.1 - 0.005 16.4 0.4 0.0059 16.1 0.3 1.1 1 0 0 1 1 1 1 Positive regulator of sigma(E), RseC/MucC BPD_transp_1 PF00528.17 EKX72684.1 - 0.025 14.0 2.2 0.031 13.7 1.5 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component VMA21 PF09446.5 EKX72684.1 - 0.098 12.5 2.3 0.14 12.1 1.6 1.2 1 0 0 1 1 1 0 VMA21-like domain G6PD_C PF02781.11 EKX72685.1 - 1.2e-58 198.3 0.0 2.5e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EKX72685.1 - 3.1e-39 135.1 0.0 6.2e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Glucosamine_iso PF01182.15 EKX72685.1 - 3.2e-36 124.9 0.0 5.3e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF2704 PF10866.3 EKX72685.1 - 0.061 12.7 0.1 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) MRP-L27 PF09809.4 EKX72687.1 - 0.078 12.5 0.0 0.27 10.8 0.0 1.9 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 SET PF00856.23 EKX72689.1 - 6.5e-05 23.2 0.1 0.00018 21.8 0.1 1.8 1 0 0 1 1 1 1 SET domain zf-C3HC4_2 PF13923.1 EKX72690.1 - 0.005 16.8 13.7 0.005 16.8 9.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKX72690.1 - 0.011 15.3 13.2 0.023 14.3 9.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EKX72690.1 - 0.021 14.6 6.5 0.045 13.5 4.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EKX72690.1 - 0.34 10.6 12.6 0.63 9.8 8.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EKX72690.1 - 1.5 8.7 12.4 2.8 7.8 8.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 EKX72690.1 - 6.4 6.7 12.4 17 5.4 8.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RLL PF10036.4 EKX72691.1 - 4e-19 69.0 0.9 1e-14 54.6 0.1 2.2 1 1 1 2 2 2 2 Putative carnitine deficiency-associated protein DUF4611 PF15387.1 EKX72691.1 - 0.049 13.7 0.2 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PUB PF09409.5 EKX72692.1 - 6.8e-12 44.9 1.1 1.9e-11 43.5 0.7 1.8 1 0 0 1 1 1 1 PUB domain DNA_ligase_A_M PF01068.16 EKX72693.1 - 2.8e-53 180.2 0.0 4.2e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EKX72693.1 - 2.6e-39 134.8 0.2 4.4e-39 134.1 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EKX72693.1 - 3e-23 82.0 0.0 5.3e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 EKX72693.1 - 0.047 13.3 0.1 0.8 9.3 0.1 2.3 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain FAINT PF04385.10 EKX72694.1 - 1.6e-10 40.6 0.2 2.6e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 DUF4028 PF13220.1 EKX72694.1 - 0.0094 15.5 0.3 0.016 14.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4028) EMA PF02488.10 EKX72694.1 - 0.15 11.4 1.3 0.27 10.6 0.9 1.3 1 1 0 1 1 1 0 Merozoite Antigen CorA PF01544.13 EKX72696.1 - 2.2e-05 23.6 1.8 2.9e-05 23.2 0.1 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Vac_Fusion PF02346.11 EKX72696.1 - 2.2 7.7 4.9 24 4.4 0.3 3.2 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Elf1 PF05129.8 EKX72697.1 - 2.3e-25 88.1 1.6 3.8e-25 87.3 1.1 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like MFS_1 PF07690.11 EKX72698.1 - 2.9e-20 72.2 14.0 2.9e-20 72.2 9.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2484 PF10658.4 EKX72698.1 - 0.077 13.1 2.6 0.67 10.1 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) FAINT PF04385.10 EKX72700.1 - 4.6e-09 35.9 0.8 2.4e-08 33.6 0.1 2.1 1 1 2 3 3 3 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72701.1 - 6.7e-49 163.6 8.7 1.1e-08 34.8 0.1 6.4 6 0 0 6 6 6 6 Domain of unknown function, DUF529 EMA PF02488.10 EKX72701.1 - 3.4e-17 62.7 18.5 2.3e-05 24.0 0.3 5.8 5 2 0 5 5 5 5 Merozoite Antigen Trp_DMAT PF11991.3 EKX72701.1 - 3e-05 23.4 0.0 0.19 10.9 0.0 2.7 3 0 0 3 3 3 2 Tryptophan dimethylallyltransferase Saf-Nte_pilin PF09460.5 EKX72701.1 - 0.00021 21.0 2.6 1.6 8.4 0.0 4.9 5 0 0 5 5 5 1 Saf-pilin pilus formation protein CBM_25 PF03423.8 EKX72701.1 - 0.0017 18.4 0.8 1.5 8.9 0.0 3.7 3 0 0 3 3 3 2 Carbohydrate binding domain (family 25) DUF3549 PF12069.3 EKX72702.1 - 0.014 14.1 0.5 0.016 14.0 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Med6 PF04934.9 EKX72703.1 - 5e-07 29.3 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 2 MED6 mediator sub complex component HECT_2 PF09814.4 EKX72704.1 - 0.00076 18.2 2.7 0.0011 17.7 1.9 1.3 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding LBP_BPI_CETP PF01273.20 EKX72704.1 - 0.016 14.5 0.1 0.045 13.1 0.0 1.7 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain RIG-I_C-RD PF11648.3 EKX72704.1 - 0.88 9.4 5.7 2.3 8.0 0.3 3.1 3 0 0 3 3 3 0 C-terminal domain of RIG-I Sua5_yciO_yrdC PF01300.13 EKX72705.1 - 5.7e-20 71.3 0.0 6.8e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EKX72707.1 - 5.3e-17 62.0 0.0 9.2e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Sua5_yciO_yrdC PF01300.13 EKX72707.1 - 6.9e-16 57.9 0.0 1.3e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination DUF3680 PF12441.3 EKX72707.1 - 0.08 12.8 0.6 0.15 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3680) SRP14 PF02290.10 EKX72708.1 - 1.7e-08 34.2 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Orbi_VP6 PF01516.11 EKX72711.1 - 0.075 12.0 7.5 0.085 11.9 5.2 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 RXT2_N PF08595.6 EKX72711.1 - 4.5 7.0 9.2 7.5 6.3 6.4 1.4 1 1 0 1 1 1 0 RXT2-like, N-terminal Collagen PF01391.13 EKX72712.1 - 0.37 10.3 14.9 1.4 8.5 10.3 1.9 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) FAINT PF04385.10 EKX72713.1 - 1.1e-15 57.2 5.0 4.3e-07 29.6 0.2 3.9 4 0 0 4 4 4 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX72713.1 - 2.3e-14 53.8 0.0 4.7e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX72713.1 - 1.1e-10 41.4 0.0 2.6e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX72713.1 - 2.3e-07 30.5 4.2 5.9e-06 26.0 0.7 3.2 2 1 1 3 3 3 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EKX72713.1 - 0.00032 19.9 0.0 0.0037 16.5 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EKX72713.1 - 0.0008 18.9 0.0 0.27 10.6 0.0 2.6 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase LIP PF03583.9 EKX72713.1 - 0.024 13.8 0.0 0.067 12.3 0.0 1.7 2 0 0 2 2 2 0 Secretory lipase Methyltransf_23 PF13489.1 EKX72713.1 - 0.046 13.4 0.0 0.19 11.4 0.0 2.0 2 1 1 3 3 3 0 Methyltransferase domain Abhydrolase_3 PF07859.8 EKX72713.1 - 0.08 12.4 0.0 0.44 10.0 0.0 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold VCBS PF13517.1 EKX72714.1 - 0.1 12.9 0.4 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella ABC_tran PF00005.22 EKX72715.1 - 2.9e-29 102.1 0.0 2.1e-17 63.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 EKX72715.1 - 2.4e-05 23.7 1.3 0.12 11.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EKX72715.1 - 0.0001 22.3 0.1 0.31 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain ArgK PF03308.11 EKX72715.1 - 0.00027 19.8 0.6 0.002 16.9 0.1 2.1 2 0 0 2 2 2 1 ArgK protein AAA_23 PF13476.1 EKX72715.1 - 0.00042 20.7 0.5 1.2 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EKX72715.1 - 0.00042 21.1 0.0 0.15 12.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EKX72715.1 - 0.00067 19.7 8.8 0.3 11.0 0.1 4.3 6 0 0 6 6 3 2 AAA domain DUF258 PF03193.11 EKX72715.1 - 0.00071 18.7 0.4 0.13 11.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EKX72715.1 - 0.0018 18.5 0.2 0.37 11.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EKX72715.1 - 0.0022 17.4 0.0 0.35 10.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EKX72715.1 - 0.0028 17.4 3.4 0.018 14.8 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_30 PF13604.1 EKX72715.1 - 0.0032 17.0 0.2 0.63 9.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EKX72715.1 - 0.0044 16.8 1.9 0.71 9.6 0.1 2.5 2 0 0 2 2 2 1 Dynamin family T2SE PF00437.15 EKX72715.1 - 0.0045 15.9 0.2 1.2 7.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EKX72715.1 - 0.0062 16.0 0.8 1.5 8.2 0.0 2.9 3 0 0 3 3 3 1 FtsK/SpoIIIE family MobB PF03205.9 EKX72715.1 - 0.0069 16.0 0.6 0.48 10.1 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EKX72715.1 - 0.012 16.0 0.3 5.9 7.4 0.1 2.6 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 EKX72715.1 - 0.018 14.1 0.2 6.1 5.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 EKX72715.1 - 0.02 15.0 0.1 6 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EKX72715.1 - 0.027 13.7 1.4 0.25 10.5 0.1 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EKX72715.1 - 0.047 13.6 0.3 0.41 10.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EKX72715.1 - 0.071 12.6 0.3 13 5.2 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 EKX72715.1 - 0.072 12.9 0.2 3.3 7.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EKX72715.1 - 0.12 11.2 0.1 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.7 EKX72715.1 - 0.14 11.7 0.7 18 4.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 EKX72715.1 - 0.37 10.5 1.4 25 4.7 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain FAINT PF04385.10 EKX72717.1 - 2.2e-10 40.2 3.2 5.5e-06 26.1 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX72717.1 - 0.0022 17.5 0.3 0.0044 16.5 0.2 1.5 1 0 0 1 1 1 1 Merozoite Antigen DUF948 PF06103.6 EKX72717.1 - 0.17 11.7 2.6 0.41 10.5 1.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_22 PF13401.1 EKX72718.1 - 5.5e-12 45.9 0.0 1.5e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EKX72718.1 - 3e-11 43.6 0.0 1e-10 41.9 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKX72718.1 - 9.5e-08 32.2 0.0 3.6e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EKX72718.1 - 0.00025 20.7 0.0 0.00044 19.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EKX72718.1 - 0.00053 19.7 0.9 0.0015 18.3 0.1 2.1 2 1 0 2 2 2 1 Archaeal ATPase DUF2075 PF09848.4 EKX72718.1 - 0.0036 16.3 0.0 0.0059 15.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EKX72718.1 - 0.0066 16.1 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EKX72718.1 - 0.0089 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EKX72718.1 - 0.021 13.5 0.1 0.06 12.0 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EKX72718.1 - 0.03 15.1 0.0 0.1 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EKX72718.1 - 0.041 13.7 0.1 0.12 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain F-box PF00646.28 EKX72718.1 - 0.052 13.2 0.4 0.12 12.0 0.2 1.8 2 0 0 2 2 1 0 F-box domain RNA_helicase PF00910.17 EKX72718.1 - 0.058 13.5 0.1 0.97 9.6 0.0 2.7 2 1 0 2 2 2 0 RNA helicase ArgK PF03308.11 EKX72718.1 - 0.097 11.4 0.3 0.17 10.6 0.2 1.2 1 0 0 1 1 1 0 ArgK protein AAA_30 PF13604.1 EKX72718.1 - 0.11 12.0 0.0 1.5 8.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain HMG_box PF00505.14 EKX72720.1 - 2.6e-23 82.0 3.5 4.6e-23 81.2 2.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EKX72720.1 - 3.8e-15 55.9 3.2 3.8e-15 55.9 2.2 1.5 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 EKX72720.1 - 0.00021 21.0 3.5 0.00021 21.0 2.4 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box 5 YABBY PF04690.8 EKX72720.1 - 0.018 15.3 0.9 0.022 15.0 0.5 1.3 1 1 0 1 1 1 0 YABBY protein DUF2582 PF10771.4 EKX72720.1 - 0.064 13.1 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2582) Peptidase_M61 PF05299.7 EKX72720.1 - 0.12 12.4 0.1 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DUF342 PF03961.8 EKX72722.1 - 1.8 6.8 20.4 1.1 7.5 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF3782 PF12644.2 EKX72722.1 - 2.6 7.9 8.6 7.5 6.4 1.5 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) FTA4 PF13093.1 EKX72722.1 - 2.7 7.3 18.8 0.014 14.8 3.8 2.4 2 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TRAUB PF08164.7 EKX72723.1 - 1e-08 35.1 2.1 1e-08 35.1 1.5 2.0 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EKX72723.1 - 0.0037 17.4 3.6 0.0037 17.4 2.5 2.2 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor Adeno_E1B_19K PF01691.11 EKX72723.1 - 0.37 10.0 2.5 0.61 9.3 0.2 2.2 2 0 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen Mlp PF03304.8 EKX72723.1 - 7.1 6.6 11.7 0.11 12.5 1.1 2.9 2 1 1 3 3 3 0 Mlp lipoprotein family FbpA PF05833.6 EKX72724.1 - 8.1e-19 67.4 0.4 1.3e-18 66.8 0.3 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF4643 PF15485.1 EKX72724.1 - 0.44 9.9 2.6 0.81 9.1 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) DUF3441 PF11923.3 EKX72725.1 - 5e-25 87.2 2.3 8.7e-25 86.5 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 EKX72725.1 - 1.7e-24 85.4 0.0 5.1e-24 83.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF814) CDC45 PF02724.9 EKX72725.1 - 0.61 8.0 18.8 0.088 10.8 10.3 1.7 2 0 0 2 2 2 0 CDC45-like protein Astro_capsid PF03115.9 EKX72725.1 - 2.4 6.3 10.0 0.16 10.1 3.5 1.5 2 0 0 2 2 2 0 Astrovirus capsid protein precursor Sporozoite_P67 PF05642.6 EKX72725.1 - 4.1 5.1 16.5 7.9 4.2 11.4 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Rav1p_C PF12234.3 EKX72726.1 - 7.1e-27 93.8 0.0 2.1e-21 75.7 0.0 2.4 2 0 0 2 2 2 2 RAVE protein 1 C terminal Peptidase_M24 PF00557.19 EKX72729.1 - 8.9e-45 152.8 0.0 1.8e-22 79.9 0.0 2.2 2 0 0 2 2 2 2 Metallopeptidase family M24 FHA PF00498.21 EKX72730.1 - 4.2e-18 65.2 0.1 1.4e-07 31.5 0.1 2.7 2 0 0 2 2 2 2 FHA domain zf-C3HC4_4 PF15227.1 EKX72730.1 - 2.9e-09 36.6 10.7 7.8e-09 35.2 7.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EKX72730.1 - 9.8e-08 31.5 4.8 2.2e-07 30.4 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKX72730.1 - 1.2e-07 31.6 9.7 3.3e-07 30.2 6.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKX72730.1 - 1.1e-06 28.1 7.6 2.9e-06 26.8 5.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKX72730.1 - 3.9e-06 26.5 8.9 3.9e-06 26.5 6.2 2.3 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.1 EKX72730.1 - 1.9e-05 24.2 1.3 3.9e-05 23.2 0.4 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EKX72730.1 - 2.3e-05 24.0 8.3 7.9e-05 22.2 5.8 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EKX72730.1 - 0.028 13.9 4.9 0.029 13.9 1.8 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain VHS PF00790.14 EKX72730.1 - 0.07 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 VHS domain zf-Nse PF11789.3 EKX72730.1 - 0.24 10.9 2.4 0.64 9.5 1.7 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EKX72730.1 - 1.9 8.6 6.0 1.3 9.1 2.2 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger FAINT PF04385.10 EKX72731.1 - 0.0016 18.2 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 DUF3098 PF11297.3 EKX72732.1 - 0.069 12.8 0.1 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) DUF1542 PF07564.6 EKX72732.1 - 0.16 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) PNK3P PF08645.6 EKX72734.1 - 0.012 15.0 0.1 0.025 14.0 0.1 1.6 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Acid_phosphat_B PF03767.9 EKX72734.1 - 0.11 11.8 0.4 0.21 10.9 0.3 1.5 1 1 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) FAINT PF04385.10 EKX72735.1 - 0.0067 16.2 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72736.1 - 2.3e-31 107.4 38.1 4.3e-05 23.2 1.5 9.4 9 0 0 9 9 9 7 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX72737.1 - 2.9e-12 46.9 0.0 7.3e-12 45.6 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family FAINT PF04385.10 EKX72737.1 - 1.1e-11 44.3 12.1 0.001 18.8 0.1 4.3 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Abhydrolase_5 PF12695.2 EKX72737.1 - 4.9e-08 32.8 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX72737.1 - 8.5e-05 22.3 0.0 0.00098 18.9 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EKX72737.1 - 0.0016 17.7 0.2 0.11 11.6 0.1 2.4 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EKX72737.1 - 0.0044 16.6 0.1 0.042 13.4 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0565 PF10561.4 EKX72737.1 - 0.0056 15.6 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 Abhydrolase_3 PF07859.8 EKX72737.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAINT PF04385.10 EKX72741.1 - 4.5e-13 48.8 0.2 2.1e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 dCMP_cyt_deam_1 PF00383.17 EKX72742.1 - 2.8e-11 42.9 0.3 4.4e-11 42.3 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region TIP120 PF08623.5 EKX72742.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) FAINT PF04385.10 EKX72744.1 - 2e-43 146.1 21.6 1.1e-08 34.8 0.0 6.6 6 0 0 6 6 6 6 Domain of unknown function, DUF529 EMA PF02488.10 EKX72744.1 - 3.3e-11 43.1 12.9 0.0039 16.7 0.3 6.0 6 0 0 6 6 6 3 Merozoite Antigen DUF3519 PF12033.3 EKX72744.1 - 0.00038 20.5 4.1 0.0015 18.7 1.4 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3519) CactinC_cactus PF09732.4 EKX72745.1 - 7.2e-48 161.3 7.5 1.9e-47 159.9 5.2 1.7 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 EKX72745.1 - 1.1e-32 112.9 2.1 1.1e-32 112.9 1.5 1.6 2 0 0 2 2 2 1 Conserved mid region of cactin PAT1 PF09770.4 EKX72745.1 - 0.0014 16.9 3.5 0.0021 16.3 2.4 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Cytochrom_C_2 PF01322.15 EKX72745.1 - 0.019 15.5 0.1 0.05 14.1 0.1 1.7 1 0 0 1 1 1 0 Cytochrome C' FAINT PF04385.10 EKX72746.1 - 6.1e-13 48.4 3.0 4.6e-08 32.7 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72747.1 - 3.7e-18 65.1 0.0 1e-07 31.7 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 EKX72747.1 - 0.0042 16.5 0.7 0.23 10.9 0.1 2.6 3 0 0 3 3 3 2 Merozoite Antigen DUF2757 PF10955.3 EKX72749.1 - 0.13 12.5 0.2 0.32 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) TarH PF02203.10 EKX72749.1 - 0.19 11.5 5.2 0.07 12.9 0.8 2.1 2 0 0 2 2 2 0 Tar ligand binding domain homologue Atg14 PF10186.4 EKX72749.1 - 2.3 7.0 9.9 5 5.9 6.8 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin-6_N PF09177.6 EKX72749.1 - 4.4 7.7 11.4 0.17 12.3 1.6 2.8 3 0 0 3 3 3 0 Syntaxin 6, N-terminal ESSS PF10183.4 EKX72750.1 - 0.44 10.9 5.5 16 5.9 0.9 3.1 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TPR_11 PF13414.1 EKX72751.1 - 5.7e-16 57.9 4.1 1.5e-08 34.1 0.0 3.0 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.1 EKX72751.1 - 4.1e-12 45.8 0.1 1.5e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EKX72751.1 - 3.1e-11 42.3 7.2 0.0011 18.7 0.1 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EKX72751.1 - 2.6e-09 36.2 3.8 0.0015 18.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKX72751.1 - 6.8e-09 34.8 7.8 0.053 13.3 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 EKX72751.1 - 1.1e-08 34.1 0.2 4e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 SHNi-TPR TPR_16 PF13432.1 EKX72751.1 - 2e-06 28.3 0.0 0.00044 20.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Syntaxin-6_N PF09177.6 EKX72751.1 - 0.00096 19.5 0.9 0.0024 18.2 0.6 1.7 1 0 0 1 1 1 1 Syntaxin 6, N-terminal TPR_7 PF13176.1 EKX72751.1 - 0.0039 16.8 0.5 5.6 7.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EKX72751.1 - 0.0048 17.0 2.3 0.15 12.2 0.4 2.9 1 1 3 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TruD PF01142.13 EKX72751.1 - 0.007 15.0 0.2 0.0091 14.6 0.2 1.2 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) TPR_14 PF13428.1 EKX72751.1 - 0.016 15.8 0.0 42 5.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF892 PF05974.7 EKX72751.1 - 0.016 15.0 2.1 0.016 15.0 0.5 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF892) SPO22 PF08631.5 EKX72751.1 - 0.043 12.9 3.7 0.83 8.6 0.0 2.5 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like 4HB_MCP_1 PF12729.2 EKX72751.1 - 0.33 10.2 7.5 1.3 8.3 5.2 2.0 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction Prefoldin PF02996.12 EKX72751.1 - 1.5 8.4 10.1 5.2 6.7 0.4 3.4 2 1 1 3 3 3 0 Prefoldin subunit DUF4200 PF13863.1 EKX72751.1 - 9.9 6.1 14.7 0.78 9.6 1.8 2.8 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) MreB_Mbl PF06723.8 EKX72752.1 - 0.16 10.5 0.0 0.33 9.5 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein DUF726 PF05277.7 EKX72753.1 - 1.6e-76 257.4 2.4 1.1e-75 254.7 1.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF726) DUF676 PF05057.9 EKX72753.1 - 0.00027 20.3 0.1 0.0014 17.9 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EKX72753.1 - 0.00058 19.4 0.1 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 EKX72753.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 EKX72753.1 - 0.0071 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.6 EKX72753.1 - 0.0097 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DDR PF08841.5 EKX72753.1 - 0.13 11.1 1.2 0.23 10.2 0.8 1.3 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain UQ_con PF00179.21 EKX72755.1 - 2.7e-53 179.1 0.1 3e-53 178.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKX72755.1 - 2.4e-06 27.3 0.0 2.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EKX72755.1 - 0.0017 18.2 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EKX72755.1 - 0.013 15.2 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 0 UEV domain NAP PF00956.13 EKX72756.1 - 1.6e-67 227.1 6.6 2.2e-67 226.7 4.6 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) FCH PF00611.18 EKX72756.1 - 0.0017 18.5 0.2 0.0078 16.3 0.1 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Mst1_SARAH PF11629.3 EKX72756.1 - 0.002 17.9 6.5 0.37 10.6 0.5 3.6 4 0 0 4 4 4 2 C terminal SARAH domain of Mst1 Phage_lysis PF03245.8 EKX72756.1 - 0.039 13.9 1.6 0.051 13.5 0.0 1.9 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein PKK PF12474.3 EKX72756.1 - 0.37 10.5 8.3 0.57 9.8 2.2 2.4 2 0 0 2 2 2 0 Polo kinase kinase Proteasome PF00227.21 EKX72757.1 - 3.9e-33 114.3 0.2 4.6e-33 114.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit FAINT PF04385.10 EKX72759.1 - 0.004 16.9 4.1 0.04 13.7 0.1 3.2 3 1 0 3 3 3 1 Domain of unknown function, DUF529 DUF2846 PF11008.3 EKX72759.1 - 0.0076 16.0 0.1 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2846) PCNA_N PF00705.13 EKX72760.1 - 1.7e-41 140.6 1.4 1.7e-41 140.6 1.0 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EKX72760.1 - 4e-27 94.6 0.0 7.4e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain DUF106 PF01956.11 EKX72761.1 - 6.1e-21 74.6 0.1 7.6e-21 74.3 0.1 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 Hydrolase_3 PF08282.7 EKX72762.1 - 2e-39 135.6 0.0 2.5e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX72762.1 - 0.00035 19.9 0.0 0.68 9.1 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EKX72762.1 - 0.028 14.5 0.3 0.094 12.8 0.2 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Fer4_19 PF06902.6 EKX72762.1 - 0.058 13.2 0.9 13 5.7 0.0 2.4 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster FAINT PF04385.10 EKX72763.1 - 2.4e-07 30.4 6.0 0.0051 16.6 0.2 2.8 3 0 0 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72764.1 - 1.1e-15 57.1 5.6 3.2e-08 33.2 0.2 4.7 4 0 0 4 4 4 3 Domain of unknown function, DUF529 Hydrolase_3 PF08282.7 EKX72765.1 - 2e-32 112.7 0.0 2.5e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKX72765.1 - 0.0002 21.5 0.1 0.00034 20.8 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX72765.1 - 0.012 14.9 0.0 0.62 9.3 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase AalphaY_MDB PF04611.7 EKX72767.1 - 0.29 11.0 0.2 1.2 8.9 0.1 2.1 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region TIP49 PF06068.8 EKX72768.1 - 6.4e-171 568.4 0.1 7.5e-171 568.2 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EKX72768.1 - 6.2e-08 32.0 0.3 2.1e-05 23.8 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA PF00004.24 EKX72768.1 - 7.8e-08 32.5 0.3 7.3e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKX72768.1 - 1.1e-07 32.0 0.0 0.0011 19.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EKX72768.1 - 1.3e-06 27.6 0.2 0.0047 16.0 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EKX72768.1 - 1.6e-05 24.0 0.0 3.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EKX72768.1 - 7.1e-05 22.8 0.1 0.001 19.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DnaB_C PF03796.10 EKX72768.1 - 0.0002 20.3 0.0 0.00038 19.4 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_17 PF13207.1 EKX72768.1 - 0.00022 22.0 0.0 0.0018 19.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EKX72768.1 - 0.00043 19.7 0.0 0.62 9.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 EKX72768.1 - 0.00047 19.9 0.1 0.073 12.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) CPT PF07931.7 EKX72768.1 - 0.00057 19.5 0.0 0.0087 15.7 0.0 2.2 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 EKX72768.1 - 0.00081 19.6 0.2 0.0064 16.8 0.0 2.7 3 1 0 3 3 1 1 AAA domain AAA_25 PF13481.1 EKX72768.1 - 0.004 16.5 0.0 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKX72768.1 - 0.0041 16.8 0.0 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_29 PF13555.1 EKX72768.1 - 0.006 16.0 0.3 0.02 14.4 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF2075 PF09848.4 EKX72768.1 - 0.0064 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Zot PF05707.7 EKX72768.1 - 0.0084 15.5 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) KaiC PF06745.8 EKX72768.1 - 0.051 12.6 0.2 0.12 11.4 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.1 EKX72768.1 - 0.17 11.7 0.0 0.62 9.9 0.0 2.0 3 0 0 3 3 3 0 AAA domain CHCH PF06747.8 EKX72771.1 - 0.0067 16.3 1.4 0.01 15.7 1.0 1.3 1 0 0 1 1 1 1 CHCH domain Colipase-like PF15083.1 EKX72771.1 - 0.024 14.5 1.0 0.029 14.3 0.7 1.1 1 0 0 1 1 1 0 Colipase-like DUF1690 PF07956.6 EKX72771.1 - 0.063 13.2 1.3 0.074 13.0 0.9 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF382 PF04037.8 EKX72774.1 - 1.2e-58 196.4 1.6 1.2e-58 196.4 1.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EKX72774.1 - 8.1e-23 79.5 3.9 2.1e-22 78.2 2.3 2.0 2 0 0 2 2 2 1 PSP Choline_kinase PF01633.15 EKX72776.1 - 1.1e-28 100.2 0.1 1.6e-28 99.7 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EKX72776.1 - 6.9e-06 25.9 0.0 9.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EKX72776.1 - 0.092 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase FAINT PF04385.10 EKX72777.1 - 2.6e-16 59.2 0.4 1.9e-05 24.4 0.0 4.0 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX72777.1 - 3.3e-13 50.0 0.0 6.2e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX72777.1 - 1.4e-08 34.4 0.4 4.4e-07 29.6 0.1 3.0 2 1 1 3 3 3 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EKX72777.1 - 2e-08 34.1 0.0 5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKX72777.1 - 0.00094 18.8 0.0 0.0053 16.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EKX72777.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.8 EKX72777.1 - 0.022 14.3 0.0 0.054 13.0 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF900 PF05990.7 EKX72777.1 - 0.027 13.7 0.3 0.16 11.2 0.0 2.3 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2305 PF10230.4 EKX72777.1 - 0.048 13.0 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) FAINT PF04385.10 EKX72780.1 - 9.2e-09 35.0 0.2 2.3e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72781.1 - 1.4e-08 34.4 4.0 0.00047 19.9 0.0 3.9 3 0 0 3 3 3 3 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72782.1 - 0.00019 21.2 0.0 0.00034 20.4 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function, DUF529 Lactococcin PF04369.8 EKX72783.1 - 0.093 12.6 0.1 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Lactococcin-like family FAINT PF04385.10 EKX72784.1 - 1.5e-07 31.1 0.0 0.0025 17.6 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72785.1 - 0.0081 15.9 0.3 0.014 15.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 DUF2300 PF10062.4 EKX72785.1 - 0.021 14.5 0.2 0.021 14.5 0.1 1.7 2 0 0 2 2 2 0 Predicted secreted protein (DUF2300) DUF1180 PF06679.7 EKX72785.1 - 6.9 6.5 6.2 12 5.7 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) FAINT PF04385.10 EKX72787.1 - 2.5e-06 27.2 0.1 4.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function, DUF529 YkuD_2 PF13645.1 EKX72787.1 - 0.0039 16.4 0.3 0.015 14.5 0.0 1.9 2 0 0 2 2 2 1 L,D-transpeptidase catalytic domain GATA PF00320.22 EKX72787.1 - 0.055 12.8 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 GATA zinc finger TPR_11 PF13414.1 EKX72788.1 - 2.5e-18 65.4 3.4 4.9e-13 48.5 0.5 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EKX72788.1 - 4.5e-18 64.0 0.8 2.9e-06 26.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKX72788.1 - 1.4e-14 52.7 0.6 2.2e-05 24.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EKX72788.1 - 1.7e-08 34.2 1.1 3.3e-06 26.9 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKX72788.1 - 1.9e-06 27.2 0.6 0.13 12.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKX72788.1 - 1.7e-05 24.2 3.6 0.00011 21.6 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EKX72788.1 - 0.00018 21.3 2.8 0.014 15.2 0.1 2.7 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 EKX72788.1 - 0.0011 18.7 0.1 5.4 6.9 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKX72788.1 - 0.0027 18.2 0.2 2.1 9.2 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKX72788.1 - 0.0064 17.1 0.3 0.71 10.6 0.0 2.6 1 1 1 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EKX72788.1 - 0.011 15.8 0.8 0.047 13.8 0.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 EKX72788.1 - 0.021 13.9 1.6 0.03 13.4 1.1 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 EKX72788.1 - 0.033 14.5 0.5 5.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EKX72788.1 - 0.11 12.6 0.3 72 3.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RNF111_N PF15303.1 EKX72789.1 - 1.5 8.2 11.4 0.057 12.9 3.7 1.7 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus Helicase_C PF00271.26 EKX72790.1 - 4.8e-17 61.5 0.0 8.2e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKX72790.1 - 8.1e-08 31.9 0.0 1.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase IZUMO PF15005.1 EKX72790.1 - 0.028 14.4 0.7 0.072 13.1 0.2 1.8 2 0 0 2 2 2 0 Izumo sperm-egg fusion Rep_fac_C PF08542.6 EKX72791.1 - 1.1e-16 60.5 1.9 2.4e-16 59.4 0.1 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.24 EKX72791.1 - 8.3e-16 58.3 0.5 2.2e-15 57.0 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EKX72791.1 - 2.8e-14 53.0 0.5 4.6e-12 45.8 0.4 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EKX72791.1 - 6.8e-08 32.4 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EKX72791.1 - 7.3e-07 28.2 0.1 0.00011 21.1 0.0 2.4 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EKX72791.1 - 3.3e-06 26.3 0.3 2e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EKX72791.1 - 4.9e-06 26.6 0.1 0.00025 21.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EKX72791.1 - 5e-06 26.6 0.3 0.00027 21.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKX72791.1 - 2.4e-05 23.9 0.0 6e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EKX72791.1 - 4.8e-05 23.0 0.1 0.00024 20.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EKX72791.1 - 6.9e-05 22.4 0.1 0.017 14.5 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain DNA_pol3_delta PF06144.8 EKX72791.1 - 7.7e-05 22.2 0.3 0.00013 21.5 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 EKX72791.1 - 0.0001 21.5 0.0 0.0019 17.4 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EKX72791.1 - 0.00022 20.8 0.2 0.0011 18.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EKX72791.1 - 0.00024 20.8 1.6 0.26 10.9 0.2 2.3 1 1 1 2 2 2 2 NTPase FtsK_SpoIIIE PF01580.13 EKX72791.1 - 0.00046 19.7 0.0 0.005 16.3 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.1 EKX72791.1 - 0.00078 19.4 0.1 0.0024 17.9 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain DEAD PF00270.24 EKX72791.1 - 0.0016 17.9 0.2 0.34 10.4 0.0 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 EKX72791.1 - 0.0021 17.5 0.1 0.0057 16.1 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.13 EKX72791.1 - 0.0025 17.3 0.0 0.0044 16.5 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 EKX72791.1 - 0.0028 17.2 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EKX72791.1 - 0.0031 16.9 0.0 0.0083 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EKX72791.1 - 0.0046 16.2 0.1 0.01 15.0 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 TIP49 PF06068.8 EKX72791.1 - 0.0063 15.2 0.1 0.093 11.4 0.0 2.0 1 1 1 2 2 2 1 TIP49 C-terminus AAA_18 PF13238.1 EKX72791.1 - 0.0096 16.2 0.0 0.022 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EKX72791.1 - 0.011 15.8 0.1 0.07 13.3 0.1 2.2 1 1 0 1 1 1 0 RNA helicase MCM PF00493.18 EKX72791.1 - 0.016 14.0 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA_24 PF13479.1 EKX72791.1 - 0.021 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EKX72791.1 - 0.03 13.2 0.0 0.054 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 EKX72791.1 - 0.033 14.0 0.2 0.067 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EKX72791.1 - 0.043 12.5 0.2 1.5 7.5 0.0 2.1 1 1 1 2 2 2 0 SNF2 family N-terminal domain PhoH PF02562.11 EKX72791.1 - 0.065 12.4 0.0 2.8 7.1 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 EKX72791.1 - 0.093 12.2 0.0 0.3 10.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EKX72791.1 - 0.096 13.5 0.1 0.24 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EKX72791.1 - 0.11 11.9 0.1 0.27 10.6 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 EKX72791.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain CobA_CobO_BtuR PF02572.10 EKX72791.1 - 0.12 11.9 0.3 20 4.7 0.0 2.6 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ArgK PF03308.11 EKX72791.1 - 0.13 11.0 0.1 0.71 8.5 0.0 2.1 2 1 1 3 3 3 0 ArgK protein KaiC PF06745.8 EKX72791.1 - 1.1 8.3 4.5 11 5.0 0.0 3.2 1 1 2 3 3 3 0 KaiC Mito_carr PF00153.22 EKX72792.1 - 5.7e-52 173.4 3.0 5.8e-20 70.8 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RBFA PF02033.13 EKX72793.1 - 6.6e-11 42.1 0.0 2.6e-10 40.2 0.0 2.0 1 0 0 1 1 1 1 Ribosome-binding factor A FAINT PF04385.10 EKX72794.1 - 2.3e-07 30.5 3.0 3.1e-05 23.7 0.6 2.8 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72795.1 - 8.9e-11 41.4 1.2 0.00017 21.3 0.1 2.7 2 1 0 2 2 2 2 Domain of unknown function, DUF529 Lipase_GDSL_3 PF14606.1 EKX72795.1 - 0.093 12.4 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family FAINT PF04385.10 EKX72796.1 - 1e-15 57.2 0.0 7.5e-05 22.5 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 EKX72796.1 - 3.9e-06 26.5 0.0 6.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 EKX72797.1 - 3.3e-07 30.0 0.8 5.3e-07 29.3 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function, DUF529 EMA PF02488.10 EKX72797.1 - 0.0012 18.3 0.2 0.0012 18.3 0.1 1.0 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 EKX72800.1 - 0.0016 18.2 2.6 0.022 14.5 0.3 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72801.1 - 3e-07 30.1 0.1 7.2e-07 28.9 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function, DUF529 DUF866 PF05907.8 EKX72801.1 - 0.037 13.5 0.1 1.2 8.6 0.0 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Saf-Nte_pilin PF09460.5 EKX72801.1 - 0.091 12.5 0.1 0.1 12.3 0.1 1.0 1 0 0 1 1 1 0 Saf-pilin pilus formation protein S4 PF01479.20 EKX72802.1 - 5e-09 35.4 0.0 9.6e-09 34.5 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EKX72802.1 - 5e-09 36.4 1.1 9.7e-09 35.5 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_S28e PF01200.13 EKX72803.1 - 1.3e-31 108.1 1.7 1.4e-31 108.0 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e FAINT PF04385.10 EKX72804.1 - 0.039 13.8 2.1 0.043 13.6 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function, DUF529 Pex14_N PF04695.8 EKX72805.1 - 0.017 15.1 0.4 0.03 14.3 0.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region POM121 PF15229.1 EKX72805.1 - 0.03 13.7 7.7 0.042 13.2 5.3 1.1 1 0 0 1 1 1 0 POM121 family vMSA PF00695.14 EKX72805.1 - 0.062 12.5 4.6 0.08 12.1 3.2 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Pneumo_phosprot PF02478.11 EKX72805.1 - 6.8 6.1 8.1 8.5 5.8 5.6 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein MORN PF02493.15 EKX72806.1 - 4.6e-27 92.0 44.8 1.4e-05 24.5 0.9 8.9 8 1 0 8 8 8 8 MORN repeat ParA PF10609.4 EKX72807.1 - 5.3e-23 80.6 0.1 8.8e-23 79.9 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EKX72807.1 - 8.1e-22 77.5 0.0 1.1e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EKX72807.1 - 4.9e-08 32.3 0.0 1.8e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EKX72807.1 - 7.3e-08 31.8 2.4 1.6e-05 24.0 0.2 2.4 2 1 1 3 3 3 2 Anion-transporting ATPase AAA_31 PF13614.1 EKX72807.1 - 1.4e-07 31.5 0.0 8e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.1 EKX72807.1 - 8.8e-05 22.1 0.1 0.29 10.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EKX72807.1 - 0.00038 19.3 0.1 0.00057 18.7 0.1 1.2 1 0 0 1 1 1 1 ArgK protein YhjQ PF06564.7 EKX72807.1 - 0.012 14.9 0.1 0.056 12.7 0.1 1.9 1 1 0 1 1 1 0 YhjQ protein APS_kinase PF01583.15 EKX72807.1 - 0.014 15.0 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.17 EKX72807.1 - 0.022 14.1 0.1 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 EKX72807.1 - 0.023 15.4 0.1 0.043 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 EKX72807.1 - 0.024 13.8 0.2 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MobB PF03205.9 EKX72807.1 - 0.028 14.1 0.1 0.098 12.3 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EKX72807.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EKX72807.1 - 0.08 12.1 0.1 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKX72807.1 - 0.088 12.7 0.1 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 EKX72807.1 - 0.092 11.5 0.2 0.18 10.6 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 EKX72807.1 - 0.1 12.3 0.6 0.18 11.5 0.1 1.6 2 0 0 2 2 2 0 NTPase KTI12 PF08433.5 EKX72807.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.9 EKX72807.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EKX72807.1 - 0.19 11.3 0.1 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain P12 PF12669.2 EKX72807.1 - 0.58 10.3 4.9 1.5 9.1 3.4 1.6 1 1 0 1 1 1 0 Virus attachment protein p12 family DNA_primase_lrg PF04104.9 EKX72808.1 - 1.6e-65 220.9 0.1 3.8e-65 219.7 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit SPRY PF00622.23 EKX72809.1 - 8.8e-10 38.7 0.1 1.7e-08 34.5 0.1 2.3 2 0 0 2 2 2 1 SPRY domain Prenyltransf PF01255.14 EKX72810.1 - 8.5e-53 178.7 0.0 6.4e-52 175.8 0.0 1.9 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF2787 PF10980.3 EKX72810.1 - 0.051 13.5 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2787) SAD_SRA PF02182.12 EKX72811.1 - 2.8e-11 42.9 0.0 5.1e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain SET PF00856.23 EKX72813.1 - 1.5e-22 80.6 0.1 9.8e-22 77.9 0.1 2.1 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EKX72813.1 - 2e-10 40.8 2.5 2e-10 40.8 1.8 1.9 2 0 0 2 2 2 1 Pre-SET motif Thioredoxin PF00085.15 EKX72814.1 - 3e-44 148.9 0.4 5.7e-27 93.4 0.1 3.6 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EKX72814.1 - 1.1e-25 90.4 3.8 3.5e-15 56.2 1.4 3.5 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EKX72814.1 - 1.4e-09 38.1 1.8 3.4e-05 23.9 0.1 4.3 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EKX72814.1 - 1.6e-08 34.5 0.9 0.036 14.1 0.0 4.4 3 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EKX72814.1 - 1.7e-08 34.3 0.6 2.7e-05 24.1 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 EKX72814.1 - 1.9e-07 30.7 0.2 0.00034 20.2 0.0 3.0 2 1 1 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 EKX72814.1 - 1.5e-05 24.5 0.2 0.0026 17.3 0.0 2.6 2 0 0 2 2 2 1 Redoxin ERp29_N PF07912.8 EKX72814.1 - 6.2e-05 22.9 0.1 0.35 10.7 0.0 2.8 2 0 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_9 PF14595.1 EKX72814.1 - 0.00056 19.4 0.0 0.029 13.9 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin TMEM154 PF15102.1 EKX72815.1 - 0.07 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family 2OG-FeII_Oxy_3 PF13640.1 EKX72816.1 - 3.9e-09 36.9 0.0 4.3e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EKX72816.1 - 2.1e-08 34.3 0.0 4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EKX72816.1 - 6.1e-05 22.5 0.0 0.00021 20.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-P11 PF03854.9 EKX72817.1 - 0.045 13.2 1.1 0.085 12.3 0.8 1.4 1 0 0 1 1 1 0 P-11 zinc finger FAINT PF04385.10 EKX72818.1 - 7e-07 28.9 0.0 0.0053 16.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Acetyltransf_2 PF00797.12 EKX72819.1 - 3.6e-73 246.0 1.0 4.3e-73 245.8 0.7 1.0 1 0 0 1 1 1 1 N-acetyltransferase FAINT PF04385.10 EKX72820.1 - 7.2e-36 121.8 19.3 1.9e-07 30.8 0.1 5.7 6 0 0 6 6 6 5 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72821.1 - 4e-06 26.5 0.7 0.057 13.2 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function, DUF529 LSM PF01423.17 EKX72824.1 - 6.6e-15 54.4 0.3 8.2e-15 54.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain tRNA-synt_1 PF00133.17 EKX72826.1 - 2.1e-41 141.6 8.0 1.6e-26 92.4 0.2 4.7 3 2 1 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EKX72826.1 - 8.8e-26 90.4 0.1 2.3e-17 62.7 0.0 3.6 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EKX72826.1 - 1.6e-11 44.1 0.1 4.9e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 EKX72826.1 - 4.8e-06 25.9 0.0 8.4e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EKX72826.1 - 0.00054 19.1 0.0 0.053 12.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain ubiquitin PF00240.18 EKX72828.1 - 1.9e-20 72.0 0.0 3.5e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKX72828.1 - 1.5e-08 34.1 0.0 3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EKX72828.1 - 2.1e-05 24.7 0.0 8.1e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EKX72828.1 - 0.04 13.8 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Methyltransf_11 PF08241.7 EKX72829.1 - 7.5e-17 61.6 0.0 1.2e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKX72829.1 - 2.5e-14 52.9 0.0 1.5e-13 50.4 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EKX72829.1 - 6.5e-11 42.0 0.0 9.8e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKX72829.1 - 2.1e-07 31.2 0.0 5e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKX72829.1 - 1.6e-06 27.9 0.0 2.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKX72829.1 - 1.3e-05 25.5 0.0 2.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EKX72829.1 - 0.0067 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_18 PF12847.2 EKX72829.1 - 0.014 15.9 0.0 0.026 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FAINT PF04385.10 EKX72830.1 - 2e-51 171.7 57.4 1.7e-05 24.5 1.9 15.5 15 0 0 15 15 15 13 Domain of unknown function, DUF529 DUF432 PF04254.8 EKX72830.1 - 0.032 14.1 0.0 0.13 12.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF432) TruB-C_2 PF09157.6 EKX72830.1 - 0.41 10.5 0.0 0.9 9.4 0.0 1.5 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal RVT_1 PF00078.22 EKX72831.1 - 1.4e-34 119.3 0.1 2.5e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PI3_PI4_kinase PF00454.22 EKX72832.1 - 0.028 13.8 1.7 0.05 13.0 0.4 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase DUF948 PF06103.6 EKX72832.1 - 0.15 11.9 12.1 2.4 8.0 0.0 5.2 4 2 2 6 6 6 0 Bacterial protein of unknown function (DUF948) Tim17 PF02466.14 EKX72835.1 - 6.9e-25 87.5 2.9 8.4e-25 87.2 2.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Aph-1 PF06105.7 EKX72835.1 - 0.0038 16.5 0.1 0.0053 16.0 0.1 1.2 1 0 0 1 1 1 1 Aph-1 protein ERO1 PF04137.10 EKX72836.1 - 4.6e-17 62.0 0.0 5.8e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ERO1 PF04137.10 EKX72838.1 - 9.7e-43 146.5 3.6 1.2e-42 146.2 2.5 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) SKG6 PF08693.5 EKX72838.1 - 0.089 12.1 3.1 0.14 11.5 1.1 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Beach PF02138.13 EKX72839.1 - 8.8e-75 251.6 0.0 1.4e-74 250.9 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EKX72839.1 - 0.11 12.3 6.7 1.5 8.8 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat 60KD_IMP PF02096.15 EKX72840.1 - 3.9e-19 69.0 0.9 5.4e-19 68.6 0.6 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF4519 PF15012.1 EKX72840.1 - 0.62 10.0 0.0 0.62 10.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) Band_7 PF01145.20 EKX72841.1 - 8.8e-30 103.9 0.4 3.6e-29 101.9 0.1 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family dNK PF01712.14 EKX72842.1 - 0.035 14.0 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase BT1 PF03092.11 EKX72843.1 - 1e-63 215.5 21.8 1.6e-63 214.9 15.1 1.2 1 0 0 1 1 1 1 BT1 family UK PF02512.9 EKX72844.1 - 0.064 13.6 0.1 0.23 11.8 0.0 2.0 1 0 0 1 1 1 0 Virulence determinant DUF713 PF05218.9 EKX72846.1 - 0.058 13.1 1.1 0.31 10.7 0.3 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF713) Glutaredoxin PF00462.19 EKX72847.1 - 0.05 13.5 1.7 0.17 11.9 0.0 2.5 2 1 0 2 2 2 0 Glutaredoxin PHD PF00628.24 EKX72847.1 - 0.063 12.9 1.9 0.13 11.9 1.3 1.5 1 0 0 1 1 1 0 PHD-finger Nrf1_DNA-bind PF10491.4 EKX72847.1 - 0.15 11.1 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 PPR_2 PF13041.1 EKX72848.1 - 3.4e-70 231.8 34.3 3.4e-15 55.7 0.1 9.2 2 1 8 10 10 10 9 PPR repeat family PPR PF01535.15 EKX72848.1 - 2.6e-51 168.0 27.7 1.2e-07 31.2 0.3 11.2 11 0 0 11 11 11 8 PPR repeat PPR_1 PF12854.2 EKX72848.1 - 3.6e-49 163.9 11.4 2.4e-08 33.3 0.1 8.8 9 0 0 9 9 9 7 PPR repeat PPR_3 PF13812.1 EKX72848.1 - 1.1e-46 153.2 0.1 2.6e-06 27.2 0.0 11.5 12 0 0 12 12 12 8 Pentatricopeptide repeat domain TPR_14 PF13428.1 EKX72848.1 - 4.5e-05 23.7 0.0 17 6.3 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat ATP13 PF12921.2 EKX72848.1 - 0.0001 21.6 0.4 3.7 6.9 0.0 5.2 5 1 0 5 5 5 1 Mitochondrial ATPase expression TPR_19 PF14559.1 EKX72848.1 - 0.00039 20.6 0.0 0.59 10.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ECSIT PF06239.6 EKX72848.1 - 0.0061 15.4 0.9 2.1 7.1 0.0 4.1 3 1 2 5 5 5 1 Evolutionarily conserved signalling intermediate in Toll pathway Apc3 PF12895.2 EKX72848.1 - 0.0088 16.1 0.7 3.2 7.9 0.0 4.4 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3212 PF11486.3 EKX72848.1 - 0.3 10.8 3.0 1.1 8.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3212) DUF849 PF05853.7 EKX72848.1 - 0.35 9.7 0.0 0.64 8.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) Brix PF04427.13 EKX72852.1 - 7.8e-39 133.3 0.4 1.1e-38 132.7 0.3 1.2 1 0 0 1 1 1 1 Brix domain Gaa1 PF04114.9 EKX72853.1 - 6.2e-21 74.6 7.9 1.9e-20 73.0 1.1 2.8 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component Vps36_ESCRT-II PF11605.3 EKX72854.1 - 0.078 12.7 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 ERCC4 PF02732.10 EKX72855.1 - 3.6e-17 62.4 0.0 1.8e-16 60.1 0.0 2.3 2 0 0 2 2 2 1 ERCC4 domain OB_NTP_bind PF07717.11 EKX72856.1 - 1.8e-24 85.7 0.0 4.3e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EKX72856.1 - 8.2e-23 80.3 0.0 5.5e-22 77.7 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EKX72856.1 - 7.1e-11 41.8 0.0 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKX72856.1 - 2.1e-07 30.6 0.0 4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKX72856.1 - 2e-06 27.9 0.0 5.8e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EKX72856.1 - 0.00089 19.1 1.1 0.7 9.6 0.0 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_14 PF13173.1 EKX72856.1 - 0.001 18.9 0.2 0.031 14.1 0.1 3.0 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EKX72856.1 - 0.0046 15.8 0.0 0.0087 14.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain SRP54 PF00448.17 EKX72856.1 - 0.0056 16.1 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EKX72856.1 - 0.0085 15.5 0.1 0.22 10.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain T2SE PF00437.15 EKX72856.1 - 0.0088 14.9 0.0 0.031 13.1 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.22 EKX72856.1 - 0.013 15.7 0.0 0.047 13.9 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 EKX72856.1 - 0.02 14.5 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PCI PF01399.22 EKX72856.1 - 0.036 14.3 0.0 0.17 12.2 0.0 2.1 1 0 0 1 1 1 0 PCI domain KaiC PF06745.8 EKX72856.1 - 0.053 12.6 0.3 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.1 EKX72856.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 EKX72856.1 - 0.72 10.1 0.0 0.72 10.1 0.0 3.8 3 1 0 3 3 2 0 AAA domain NUC173 PF08161.7 EKX72857.1 - 8.3e-08 31.8 0.0 2.4e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 NUC173 domain CTD_bind PF04818.8 EKX72859.1 - 2.6e-06 27.5 0.1 7.7e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Vps16_C PF04840.7 EKX72860.1 - 0.012 14.5 0.1 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Vps16, C-terminal region Unstab_antitox PF09720.5 EKX72860.1 - 0.046 13.4 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 Putative addiction module component TRCF PF03461.10 EKX72860.1 - 0.055 13.4 0.1 0.1 12.5 0.1 1.6 1 1 0 1 1 1 0 TRCF domain DUF4602 PF15375.1 EKX72862.1 - 2.9e-07 30.6 10.9 4.7e-07 29.9 7.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) tRNA-synt_2 PF00152.15 EKX72863.1 - 2.2e-86 289.6 0.1 2.2e-67 227.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EKX72863.1 - 2.2e-10 40.2 0.0 5.3e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EKX72863.1 - 6.2e-10 38.6 0.2 2.4e-05 23.6 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EKX72863.1 - 0.00088 18.9 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) LSM PF01423.17 EKX72864.1 - 1.4e-13 50.1 0.0 1.5e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.15 EKX72865.1 - 2.2e-45 154.3 0.1 5.8e-45 152.9 0.0 1.7 2 0 0 2 2 2 1 3'-5' exonuclease Rhabdo_glycop PF00974.13 EKX72865.1 - 0.067 11.4 0.0 0.13 10.5 0.0 1.4 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein ERCC4 PF02732.10 EKX72867.1 - 6.3e-24 84.3 0.0 1.1e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain GvpG PF05120.7 EKX72867.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Gas vesicle protein G SNARE PF05739.14 EKX72868.1 - 0.013 15.1 2.5 0.013 15.1 1.7 2.9 4 0 0 4 4 4 0 SNARE domain Syntaxin_2 PF14523.1 EKX72868.1 - 0.02 14.9 3.4 0.02 14.9 2.3 2.2 2 0 0 2 2 2 0 Syntaxin-like protein DUF948 PF06103.6 EKX72868.1 - 0.036 13.9 2.9 0.24 11.2 0.0 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF818 PF05677.7 EKX72870.1 - 0.002 16.9 0.0 0.002 16.9 0.0 1.9 2 0 0 2 2 2 1 Chlamydia CHLPS protein (DUF818) Xpo1 PF08389.7 EKX72872.1 - 0.00038 20.3 1.2 0.00038 20.3 0.8 4.7 6 0 0 6 6 6 2 Exportin 1-like protein TFIIB PF00382.14 EKX72873.1 - 6.5e-25 86.7 0.0 8.2e-13 47.9 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EKX72873.1 - 3.7e-15 55.9 7.3 6.8e-15 55.0 5.1 1.4 1 0 0 1 1 1 1 Brf1-like TBP-binding domain A2L_zn_ribbon PF08792.5 EKX72873.1 - 1.6e-06 27.3 0.8 9.8e-06 24.8 0.8 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.7 EKX72873.1 - 9.3e-05 21.6 0.6 0.0002 20.5 0.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding FAINT PF04385.10 EKX72875.1 - 0.0011 18.7 1.4 0.0016 18.2 0.9 1.4 1 1 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX72877.1 - 3.7e-14 52.3 16.7 1.3e-08 34.5 0.5 4.1 3 1 1 4 4 4 3 Domain of unknown function, DUF529 EMA PF02488.10 EKX72877.1 - 0.00012 21.6 1.9 0.0027 17.2 0.1 2.4 2 1 0 2 2 2 2 Merozoite Antigen E1-E2_ATPase PF00122.15 EKX72878.1 - 1.5e-22 79.7 0.1 3.8e-22 78.4 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EKX72878.1 - 1.9e-13 51.0 0.0 3.5e-06 27.3 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKX72878.1 - 7.9e-13 49.3 0.0 5.2e-07 30.2 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 EKX72879.1 - 2.3e-11 43.0 27.8 3.2e-11 42.5 19.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DEAD PF00270.24 EKX72880.1 - 7.8e-35 119.8 0.0 1.2e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKX72880.1 - 1.6e-25 88.7 0.0 1.2e-24 85.9 0.0 2.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EKX72880.1 - 0.02 13.3 0.2 0.031 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 EKX72880.1 - 0.035 13.1 0.0 0.07 12.1 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PITH PF06201.8 EKX72881.1 - 9.7e-31 106.5 1.2 1.2e-30 106.2 0.8 1.1 1 0 0 1 1 1 1 PITH domain Ribosomal_L37ae PF01780.14 EKX72882.1 - 7.2e-39 131.5 5.7 8.4e-39 131.3 3.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EKX72882.1 - 5.6e-05 22.8 2.3 8.3e-05 22.3 1.6 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EKX72882.1 - 0.0095 15.5 0.6 0.015 14.9 0.4 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Lar_restr_allev PF14354.1 EKX72882.1 - 0.018 15.3 1.5 0.03 14.6 1.0 1.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar A2L_zn_ribbon PF08792.5 EKX72882.1 - 0.022 14.2 3.3 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.1 EKX72882.1 - 0.036 14.3 1.5 0.65 10.3 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 EKX72882.1 - 0.037 13.7 3.0 0.28 10.9 0.3 2.3 1 1 1 2 2 2 0 BED zinc finger Terminase_GpA PF05876.7 EKX72882.1 - 0.053 11.8 0.5 0.057 11.7 0.4 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-Di19 PF05605.7 EKX72882.1 - 0.055 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 EKX72882.1 - 0.066 13.1 1.5 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 EKX72882.1 - 0.072 12.7 2.1 0.15 11.7 1.3 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Sgf11 PF08209.6 EKX72882.1 - 0.11 11.8 0.7 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2_4 PF13894.1 EKX72882.1 - 0.14 12.5 0.8 2.5 8.6 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4428 PF14471.1 EKX72882.1 - 0.51 10.1 3.0 0.27 11.0 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C2H2 PF00096.21 EKX72882.1 - 1.6 9.2 4.7 4.5 7.8 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-XS PF03470.9 EKX72882.1 - 3.1 7.9 5.0 29 4.8 0.1 3.1 3 0 0 3 3 3 0 XS zinc finger domain Ribosomal_L44 PF00935.14 EKX72882.1 - 9.3 6.3 9.7 3.6 7.6 1.7 2.5 1 1 1 2 2 2 0 Ribosomal protein L44 SecE PF00584.15 EKX72883.1 - 5.1e-13 48.3 0.1 6.3e-13 48.0 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex SNF PF00209.13 EKX72884.1 - 8.3e-15 54.2 34.3 1.3e-14 53.6 23.8 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF438 PF04282.8 EKX72884.1 - 0.17 11.7 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF438) Myb_DNA-bind_6 PF13921.1 EKX72885.1 - 0.01 15.9 0.0 0.029 14.4 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Atg14 PF10186.4 EKX72885.1 - 0.9 8.4 6.1 15 4.4 3.9 2.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 NAD_kinase PF01513.16 EKX72886.1 - 8.8e-57 192.0 0.1 1.1e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EKX72886.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain YgbB PF02542.11 EKX72887.1 - 2.4e-54 183.4 0.1 3e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 YgbB family Abhydrolase_5 PF12695.2 EKX72890.1 - 2.6e-21 75.8 0.0 3.6e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKX72890.1 - 2.9e-12 46.9 0.0 5.1e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKX72890.1 - 9.3e-09 35.1 0.1 0.00064 19.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKX72890.1 - 0.00024 20.3 0.0 0.0065 15.7 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EKX72890.1 - 0.00027 20.7 0.2 0.00051 19.8 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 EKX72890.1 - 0.0058 16.5 0.0 0.0097 15.7 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.8 EKX72890.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) MoaE PF02391.12 EKX72890.1 - 0.031 14.0 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 MoaE protein LIP PF03583.9 EKX72890.1 - 0.062 12.4 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Mt_ATP-synt_B PF05405.9 EKX72891.1 - 0.12 11.7 2.6 0.26 10.7 0.1 2.8 4 0 0 4 4 4 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SF3a60_bindingd PF12108.3 EKX72891.1 - 0.34 10.4 2.9 2.7 7.6 0.1 2.8 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Mito_carr PF00153.22 EKX72892.1 - 1.4e-66 220.2 0.0 8.7e-23 79.8 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4199 PF13858.1 EKX72892.1 - 0.093 12.6 1.0 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Peptidase_C1 PF00112.18 EKX72895.1 - 5.7e-25 88.4 8.7 1.3e-19 70.9 6.4 2.9 2 1 0 2 2 2 2 Papain family cysteine protease CathepsinC_exc PF08773.6 EKX72895.1 - 2.6e-06 27.5 0.0 0.001 19.2 0.0 2.6 2 0 0 2 2 2 2 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.10 EKX72895.1 - 2.4e-05 23.0 1.1 0.0097 14.4 0.5 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Med4 PF10018.4 EKX72897.1 - 0.051 12.9 0.3 0.069 12.5 0.2 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 AAA PF00004.24 EKX72899.1 - 2.9e-42 143.9 0.0 5.3e-42 143.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EKX72899.1 - 1.1e-16 60.4 0.0 3.6e-15 55.5 0.0 2.8 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EKX72899.1 - 4.8e-16 58.3 2.9 1.4e-15 56.9 2.0 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_25 PF13481.1 EKX72899.1 - 2.1e-06 27.2 0.4 0.054 12.8 0.1 2.6 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 EKX72899.1 - 3e-06 26.4 0.0 5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EKX72899.1 - 3.7e-06 26.9 0.0 7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EKX72899.1 - 2.2e-05 24.6 0.2 0.0011 19.1 0.1 2.9 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EKX72899.1 - 3.5e-05 23.5 0.0 0.00013 21.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EKX72899.1 - 5.5e-05 23.0 0.0 0.00025 20.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKX72899.1 - 9.3e-05 23.2 0.0 0.00031 21.5 0.0 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EKX72899.1 - 0.00021 20.7 0.0 0.00052 19.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 EKX72899.1 - 0.00022 20.9 0.1 0.011 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKX72899.1 - 0.00034 20.6 0.0 0.0037 17.2 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EKX72899.1 - 0.00042 20.2 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_Hsp90 PF03225.9 EKX72899.1 - 0.00044 18.6 0.2 0.00066 18.0 0.2 1.2 1 0 0 1 1 1 1 Viral heat shock protein Hsp90 homologue TIP49 PF06068.8 EKX72899.1 - 0.00058 18.6 0.0 0.00099 17.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus KaiC PF06745.8 EKX72899.1 - 0.0015 17.7 0.1 0.5 9.4 0.0 2.4 1 1 1 2 2 2 1 KaiC ResIII PF04851.10 EKX72899.1 - 0.0024 17.7 0.0 0.0045 16.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 EKX72899.1 - 0.003 16.7 0.0 0.007 15.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EKX72899.1 - 0.0044 17.3 0.0 0.014 15.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EKX72899.1 - 0.0058 16.1 0.0 0.39 10.1 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.11 EKX72899.1 - 0.0069 15.6 0.4 0.019 14.1 0.1 1.8 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 EKX72899.1 - 0.0073 16.0 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EKX72899.1 - 0.0085 16.2 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Parvo_NS1 PF01057.12 EKX72899.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EKX72899.1 - 0.027 13.3 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ocr PF08684.5 EKX72899.1 - 0.05 13.6 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 DNA mimic ocr Bac_DnaA PF00308.13 EKX72899.1 - 0.081 12.5 0.0 0.27 10.8 0.0 1.9 2 1 0 2 2 2 0 Bacterial dnaA protein Zeta_toxin PF06414.7 EKX72899.1 - 0.089 11.8 0.0 0.33 10.0 0.0 1.7 1 1 1 2 2 2 0 Zeta toxin EF1G PF00647.14 EKX72899.1 - 0.1 12.3 0.4 0.22 11.2 0.3 1.5 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain NACHT PF05729.7 EKX72899.1 - 0.11 12.1 0.0 0.67 9.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 EKX72899.1 - 0.12 12.0 0.0 12 5.6 0.0 2.3 1 1 1 2 2 2 0 NTPase TPR_11 PF13414.1 EKX72899.1 - 0.13 11.9 0.9 0.29 10.7 0.6 1.6 1 0 0 1 1 1 0 TPR repeat UIM PF02809.15 EKX72899.1 - 0.14 11.8 0.5 0.34 10.5 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif TPR_1 PF00515.23 EKX72899.1 - 0.59 9.8 3.5 2.5 7.8 2.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EKX72899.1 - 1.3 9.1 6.6 0.67 10.0 1.7 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Pro_isomerase PF00160.16 EKX72900.1 - 1.4e-49 168.3 0.0 1.6e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EKX72901.1 - 5e-08 32.5 8.2 0.0044 16.8 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat STT3 PF02516.9 EKX72902.1 - 1.3e-53 182.7 37.4 1.1e-52 179.6 25.9 2.0 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit BT1 PF03092.11 EKX72903.1 - 1.3e-50 172.4 19.6 6.6e-50 170.0 13.6 1.8 1 1 0 1 1 1 1 BT1 family MFS_1 PF07690.11 EKX72903.1 - 1e-12 47.4 49.4 1.5e-10 40.3 18.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF676 PF05057.9 EKX72904.1 - 1.5e-11 43.9 0.2 1e-09 37.9 0.1 2.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGI PF00342.14 EKX72905.1 - 1.4e-164 548.1 0.0 1.7e-164 547.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Abhydrolase_6 PF12697.2 EKX72906.1 - 2.3e-14 53.8 0.0 6.8e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX72906.1 - 6.9e-12 45.3 0.0 2.1e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family FAINT PF04385.10 EKX72906.1 - 7.7e-11 41.6 10.4 0.0034 17.1 0.0 6.4 5 1 0 5 5 5 3 Domain of unknown function, DUF529 Hydrolase_4 PF12146.3 EKX72906.1 - 3.9e-09 36.2 0.5 3.8e-08 33.0 0.2 2.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 EKX72906.1 - 0.0011 18.8 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein DUF676 PF05057.9 EKX72906.1 - 0.006 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_2 PF02230.11 EKX72906.1 - 0.0061 16.0 0.1 1.9 7.8 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF829 PF05705.9 EKX72906.1 - 0.012 15.2 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Abhydrolase_1 PF00561.15 EKX72906.1 - 0.062 12.8 0.1 1.5 8.2 0.1 2.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EKX72906.1 - 0.065 12.8 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.16 EKX72906.1 - 0.1 11.8 0.9 0.52 9.4 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family DUF3783 PF12646.2 EKX72907.1 - 0.08 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) PAH PF02671.16 EKX72907.1 - 0.12 12.0 0.3 0.25 10.9 0.2 1.6 1 0 0 1 1 1 0 Paired amphipathic helix repeat PIG-U PF06728.8 EKX72908.1 - 3.6e-31 108.3 30.4 2.4e-30 105.6 21.0 1.9 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U WGG PF10273.4 EKX72908.1 - 2.7e-18 65.8 0.3 8e-18 64.3 0.2 1.7 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 ER_lumen_recept PF00810.13 EKX72909.1 - 6.9e-38 130.4 8.6 6.9e-38 130.4 6.0 2.5 3 0 0 3 3 3 1 ER lumen protein retaining receptor Cytomega_TRL10 PF06084.6 EKX72909.1 - 0.65 9.7 3.8 4.2 7.1 0.5 2.4 1 1 1 2 2 2 0 Cytomegalovirus TRL10 protein CLTH PF10607.4 EKX72910.1 - 7.6e-14 51.6 2.4 4.8e-13 49.0 0.0 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain DUF3834 PF12916.2 EKX72910.1 - 0.89 8.5 5.2 0.81 8.6 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3834) MFS_1 PF07690.11 EKX72911.1 - 8.8e-20 70.7 28.4 8.8e-20 70.7 19.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKX72911.1 - 4.5e-06 25.5 15.8 4.5e-06 25.5 10.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EKX72911.1 - 0.00022 19.4 31.6 0.012 13.6 4.4 4.1 2 2 2 4 4 4 4 Organic Anion Transporter Polypeptide (OATP) family Arf PF00025.16 EKX72912.1 - 1e-15 57.3 0.0 1.4e-14 53.7 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKX72912.1 - 2.3e-07 30.4 0.0 6.4e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 EKX72912.1 - 2.1e-05 25.0 0.3 0.00032 21.1 0.2 2.4 1 1 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EKX72912.1 - 0.0016 17.6 0.5 0.11 11.6 0.3 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EKX72912.1 - 0.025 14.0 0.0 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EKX72912.1 - 0.041 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 EKX72912.1 - 0.044 13.7 0.1 0.61 10.0 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EKX72912.1 - 0.097 12.9 0.1 0.18 12.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter RRM_1 PF00076.17 EKX72914.1 - 6.2e-15 54.5 0.6 1.2e-14 53.6 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX72914.1 - 4.3e-11 42.6 0.0 7e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX72914.1 - 1.5e-10 40.7 0.2 2.2e-10 40.1 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EKX72914.1 - 3.8 7.1 29.1 7.5 6.2 20.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) UQ_con PF00179.21 EKX72915.1 - 1.7e-48 163.5 0.0 2e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKX72915.1 - 0.0012 18.5 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EKX72915.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain Nudc_N PF14050.1 EKX72916.1 - 3.1e-16 59.0 1.5 5.6e-16 58.2 1.0 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.11 EKX72916.1 - 5.8e-14 52.3 1.2 1.2e-13 51.4 0.9 1.5 1 0 0 1 1 1 1 CS domain DUF4160 PF13711.1 EKX72916.1 - 0.057 13.2 0.6 3.7 7.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) TetR_C_8 PF14278.1 EKX72916.1 - 1.1 9.6 4.8 3.3 8.1 1.0 3.2 3 1 0 3 3 3 0 Transcriptional regulator C-terminal region SecIII_SopE_N PF05364.9 EKX72919.1 - 0.025 14.4 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus CENP-Q PF13094.1 EKX72919.1 - 0.13 12.2 4.6 0.26 11.3 2.0 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-F_leu_zip PF10473.4 EKX72919.1 - 0.4 10.5 6.6 0.16 11.8 2.2 2.0 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-RanBP PF00641.13 EKX72920.1 - 3.5e-05 22.8 6.9 9.6e-05 21.4 4.8 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-U1 PF06220.7 EKX72921.1 - 3.3e-19 68.1 2.7 4.4e-19 67.7 1.9 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EKX72921.1 - 0.0053 16.8 3.8 0.0099 15.9 2.7 1.5 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Ribosomal_L12 PF00542.14 EKX72922.1 - 7e-10 38.7 1.7 3.4e-09 36.5 0.1 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EKX72922.1 - 0.037 14.4 3.9 0.037 14.4 2.7 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein DivIC PF04977.10 EKX72924.1 - 4.9 6.6 12.0 19 4.8 0.1 3.9 4 0 0 4 4 4 0 Septum formation initiator IncA PF04156.9 EKX72924.1 - 9.1 5.8 14.9 1 8.9 0.0 2.9 2 1 0 2 2 2 0 IncA protein CS PF04969.11 EKX72925.1 - 1.8e-10 41.2 4.9 4.8e-10 39.8 3.4 1.8 1 0 0 1 1 1 1 CS domain DnaJ PF00226.26 EKX72926.1 - 6.1e-07 29.0 0.6 1.6e-06 27.7 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain HSCB_C PF07743.8 EKX72926.1 - 8.1e-06 26.2 0.7 1.3e-05 25.5 0.1 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain 4HB_MCP_1 PF12729.2 EKX72926.1 - 1.3 8.2 7.1 1.8 7.8 0.2 2.2 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Biotin_lipoyl PF00364.17 EKX72927.1 - 1e-11 44.2 0.1 1.7e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.14 EKX72927.1 - 7.9e-05 22.3 0.2 0.00042 19.9 0.0 1.9 1 1 1 2 2 2 1 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.1 EKX72927.1 - 0.015 14.9 0.0 0.067 12.8 0.0 2.0 2 0 0 2 2 2 0 Biotin-lipoyl like Aldo_ket_red PF00248.16 EKX72928.1 - 2e-55 187.6 0.0 2.8e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Citrate_synt PF00285.16 EKX72929.1 - 3e-21 75.5 0.0 5.5e-21 74.6 0.0 1.4 1 1 0 1 1 1 1 Citrate synthase Citrate_synt PF00285.16 EKX72930.1 - 0.0012 17.6 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase IRF-3 PF10401.4 EKX72931.1 - 0.026 14.1 0.1 0.47 9.9 0.0 2.2 2 0 0 2 2 2 0 Interferon-regulatory factor 3 RRM_1 PF00076.17 EKX72932.1 - 6.9e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX72932.1 - 0.00046 20.1 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EKX72933.1 - 2.8e-39 134.8 0.0 3.2e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX72933.1 - 1.7e-16 60.0 0.0 2.3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKX72933.1 - 5.8e-06 26.2 0.0 0.00092 19.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EKX72933.1 - 0.0086 14.9 0.1 0.0086 14.9 0.1 1.5 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EKX72933.1 - 0.074 11.9 0.0 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 EKX72933.1 - 0.077 12.0 0.1 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SMC_N PF02463.14 EKX72935.1 - 1.3e-41 142.3 39.5 3.3e-39 134.4 27.4 4.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EKX72935.1 - 5.2e-20 71.6 0.1 1.8e-19 69.8 0.1 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EKX72935.1 - 2.5e-15 57.3 32.9 2.5e-15 57.3 22.8 7.2 1 1 2 3 3 3 1 AAA domain AAA_21 PF13304.1 EKX72935.1 - 5.7e-13 49.4 13.1 3.4e-09 37.0 2.6 4.6 3 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EKX72935.1 - 9.5e-05 21.8 0.0 0.00025 20.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF1409 PF07197.7 EKX72935.1 - 0.15 12.1 8.8 3.3 7.8 0.1 5.2 4 1 0 4 4 4 0 Protein of unknown function (DUF1409) DUF3584 PF12128.3 EKX72935.1 - 0.27 8.4 77.5 0.15 9.3 26.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 EKX72935.1 - 0.3 10.2 45.7 0.015 14.4 1.5 5.4 2 2 3 5 5 5 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EKX72935.1 - 0.37 11.0 0.0 0.37 11.0 0.0 6.4 4 2 1 5 5 5 0 ABC transporter WXG100 PF06013.7 EKX72935.1 - 1.9 8.5 26.9 0.12 12.4 0.6 7.6 6 2 1 7 7 7 0 Proteins of 100 residues with WXG FAINT PF04385.10 EKX72937.1 - 2.1e-08 33.9 4.8 2.3e-07 30.5 0.1 3.4 2 1 2 4 4 4 3 Domain of unknown function, DUF529 Methyltransf_8 PF05148.10 EKX72938.1 - 3.1e-70 236.2 0.0 3.9e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EKX72938.1 - 2e-05 24.9 0.1 0.00012 22.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKX72938.1 - 0.0053 16.4 0.0 0.012 15.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKX72938.1 - 0.015 14.7 0.0 0.86 8.9 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase small domain AAA_21 PF13304.1 EKX72938.1 - 1.2 9.0 6.1 0.25 11.2 1.1 1.8 2 0 0 2 2 2 0 AAA domain Elong-fact-P_C PF09285.6 EKX72939.1 - 4.8e-11 41.8 0.2 1.4e-10 40.3 0.1 1.9 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.7 EKX72939.1 - 0.00067 19.4 0.0 0.0018 18.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.15 EKX72939.1 - 0.083 12.5 0.0 0.68 9.6 0.0 2.2 1 1 1 2 2 2 0 Elongation factor P (EF-P) OB domain Asp PF00026.18 EKX72940.1 - 1.3e-61 208.6 0.0 2e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EKX72940.1 - 7e-05 22.8 0.1 0.00026 21.0 0.0 2.1 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal DUF2082 PF09855.4 EKX72941.1 - 0.53 10.1 6.7 1.1 9.1 0.1 3.2 3 0 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Arv1 PF04161.8 EKX72943.1 - 3.5e-23 82.5 19.1 3.4e-20 72.8 13.3 2.4 1 1 0 1 1 1 1 Arv1-like family Zn_Tnp_IS1595 PF12760.2 EKX72943.1 - 1.4 8.8 5.1 4.3 7.2 3.6 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain RF-1 PF00472.15 EKX72944.1 - 9.9e-32 109.1 0.4 2.1e-31 108.0 0.3 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EKX72944.1 - 1.7e-12 47.0 1.1 3.4e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 PCRF domain SEP PF08059.8 EKX72945.1 - 6.6e-17 61.5 0.1 1.5e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 SEP domain Ribosomal_S6 PF01250.12 EKX72945.1 - 2.4e-05 24.0 0.1 4.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6 UBX PF00789.15 EKX72945.1 - 0.0001 22.2 0.0 0.00035 20.5 0.0 1.9 2 0 0 2 2 2 1 UBX domain Pkinase PF00069.20 EKX72948.1 - 1.8e-37 128.9 0.0 2.7e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX72948.1 - 2.6e-23 82.4 0.0 1.3e-22 80.1 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EKX72948.1 - 0.011 14.5 1.1 0.013 14.3 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EKX72948.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-CCCH PF00642.19 EKX72950.1 - 1.6e-10 40.4 12.9 6.7e-06 25.6 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EKX72950.1 - 1.4e-09 37.6 0.0 2.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKX72950.1 - 0.00036 20.1 0.0 0.0011 18.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX72950.1 - 0.041 13.8 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LRV_FeS PF05484.6 EKX72950.1 - 0.068 12.7 2.1 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 LRV protein FeS4 cluster Proteasome PF00227.21 EKX72951.1 - 2.4e-36 124.8 0.0 4.6e-36 123.8 0.0 1.5 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EKX72951.1 - 5.4e-14 51.1 0.1 8.6e-14 50.5 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RecA PF00154.16 EKX72951.1 - 0.07 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PROCN PF08083.6 EKX72952.1 - 4e-213 707.3 7.8 5.9e-213 706.7 5.4 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EKX72952.1 - 1.4e-121 404.1 0.3 2.3e-121 403.4 0.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EKX72952.1 - 7e-92 305.0 2.9 1.3e-91 304.1 2.0 1.5 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EKX72952.1 - 7.3e-80 265.9 3.4 1.7e-79 264.7 2.3 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EKX72952.1 - 1.6e-68 228.5 0.1 3.2e-68 227.5 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EKX72952.1 - 2.1e-42 142.9 0.5 5.1e-42 141.6 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EKX72952.1 - 2.9e-32 110.9 0.1 7.6e-32 109.6 0.1 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain EamA PF00892.15 EKX72953.1 - 5.8e-09 36.0 0.4 5.8e-09 36.0 0.3 2.3 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EKX72953.1 - 0.00031 20.9 0.3 0.00031 20.9 0.2 2.1 1 1 1 2 2 2 1 Multidrug resistance efflux transporter Asp-Al_Ex PF06826.7 EKX72953.1 - 0.00066 19.2 3.3 0.05 13.1 1.3 2.3 1 1 1 2 2 2 2 Predicted Permease Membrane Region PhaG_MnhG_YufB PF03334.9 EKX72953.1 - 0.022 14.7 1.9 0.022 14.7 1.3 2.3 2 1 0 2 2 2 0 Na+/H+ antiporter subunit DUF485 PF04341.7 EKX72953.1 - 8.4 6.1 6.5 0.59 9.8 0.3 2.3 3 1 0 3 3 3 0 Protein of unknown function, DUF485 AAA PF00004.24 EKX72955.1 - 4.2e-08 33.4 0.0 6.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KH_dom-like PF14714.1 EKX72956.1 - 2.5e-22 78.6 0.0 9e-22 76.8 0.0 2.0 2 0 0 2 2 2 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal MMR_HSR1 PF01926.18 EKX72956.1 - 8.1e-21 74.1 0.5 1.7e-18 66.6 0.1 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKX72956.1 - 4.9e-07 29.1 0.0 2.8e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EKX72956.1 - 5.2e-06 25.7 0.0 2.8e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EKX72956.1 - 2.3e-05 23.9 0.0 0.2 11.0 0.1 3.9 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EKX72956.1 - 0.00012 21.3 0.1 0.00021 20.4 0.1 1.4 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 EKX72956.1 - 0.0022 17.2 0.1 0.095 11.9 0.0 3.0 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EKX72956.1 - 0.011 16.2 0.1 1.8 9.0 0.0 3.3 2 2 0 2 2 2 0 Miro-like protein HLH PF00010.21 EKX72956.1 - 0.061 13.0 1.6 0.14 11.8 0.5 2.1 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain AAA_29 PF13555.1 EKX72956.1 - 0.085 12.3 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 EKX72956.1 - 0.13 12.0 3.2 0.55 10.0 0.3 2.8 3 0 0 3 3 3 0 Dynamin family AAA_21 PF13304.1 EKX72956.1 - 0.19 11.6 4.8 0.44 10.4 3.3 1.7 1 1 0 1 1 1 0 AAA domain SCAMP PF04144.8 EKX72958.1 - 0.00072 19.4 0.1 0.00094 19.1 0.1 1.1 1 0 0 1 1 1 1 SCAMP family BolA PF01722.13 EKX72959.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 BolA-like protein rve_2 PF13333.1 EKX72959.1 - 0.061 13.4 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Peptidase_C1 PF00112.18 EKX72960.1 - 1.3e-59 201.7 0.7 2e-59 201.1 0.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKX72960.1 - 2.8e-08 33.8 3.1 8.3e-08 32.3 2.2 1.9 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EKX72960.1 - 5.5e-05 21.8 0.4 0.0043 15.6 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Lectin_N PF03954.9 EKX72960.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF3650 PF12368.3 EKX72960.1 - 0.16 11.4 0.8 28 4.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) GTP_EFTU PF00009.22 EKX72961.1 - 4.6e-44 150.1 0.0 8.7e-44 149.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EKX72961.1 - 1.5e-07 31.1 0.1 3.9e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus Miro PF08477.8 EKX72961.1 - 0.00037 20.9 0.0 0.00084 19.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 EKX72961.1 - 0.0012 17.8 1.0 0.012 14.6 0.1 2.2 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EKX72961.1 - 0.0022 17.9 0.1 0.0049 16.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EKX72961.1 - 0.0099 15.0 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 AIG1 family EFG_II PF14492.1 EKX72961.1 - 0.026 14.3 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EKX72961.1 - 0.041 14.0 0.7 0.13 12.4 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 2 ATP-synt_Eps PF04627.8 EKX72962.1 - 3.8e-05 23.1 0.0 4.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF2729 PF10870.3 EKX72962.1 - 0.11 12.2 0.1 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) MIF4G PF02854.14 EKX72965.1 - 3.8e-25 88.5 2.3 4.7e-25 88.2 1.6 1.1 1 0 0 1 1 1 1 MIF4G domain WD40 PF00400.27 EKX72966.1 - 1.6e-06 27.7 12.5 0.19 11.6 0.0 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKX72966.1 - 0.0024 17.6 0.1 5.8 6.7 0.0 3.8 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region BofC_C PF08955.5 EKX72966.1 - 0.12 12.4 0.0 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 BofC C-terminal domain tRNA_anti-codon PF01336.20 EKX72968.1 - 0.019 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Frataxin_Cyay PF01491.11 EKX72969.1 - 6.1e-20 71.0 1.0 1.5e-19 69.7 0.1 2.2 2 0 0 2 2 2 1 Frataxin-like domain Ribosomal_L2_C PF03947.13 EKX72970.1 - 1.6e-45 154.1 0.1 2.3e-45 153.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EKX72970.1 - 1.3e-25 89.1 0.3 4e-25 87.5 0.2 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PRP38 PF03371.10 EKX72971.1 - 1.6e-60 203.6 0.0 1.9e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 PRP38 family CKS PF01111.14 EKX72972.1 - 1.9e-16 59.6 1.5 3.2e-16 58.9 0.2 2.1 2 1 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Baculo_LEF-11 PF06385.7 EKX72973.1 - 0.056 13.5 1.6 0.12 12.4 1.1 1.6 1 0 0 1 1 1 0 Baculovirus LEF-11 protein S1-P1_nuclease PF02265.11 EKX72974.1 - 5.8e-10 39.2 0.0 4.6e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 S1/P1 Nuclease UPF0104 PF03706.8 EKX72974.1 - 0.39 9.9 4.5 0.74 9.0 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0104) FAINT PF04385.10 EKX72976.1 - 9.7e-19 67.0 18.6 5.7e-06 26.0 1.6 5.2 5 0 0 5 5 5 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX72976.1 - 3.6e-10 40.1 0.0 1.6e-09 38.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX72976.1 - 6e-09 35.8 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKX72976.1 - 0.00014 21.5 0.0 0.0017 17.9 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EKX72976.1 - 0.019 14.3 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 EKX72976.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Hydrolase_4 PF12146.3 EKX72976.1 - 0.11 12.3 0.2 1.5 8.7 0.1 2.6 2 0 0 2 2 2 0 Putative lysophospholipase Autophagy_act_C PF03987.10 EKX72977.1 - 4.4e-21 74.8 0.1 8.3e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_N PF03986.8 EKX72977.1 - 0.016 14.9 0.6 0.026 14.2 0.4 1.4 1 1 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF2080 PF09853.4 EKX72977.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) RabGAP-TBC PF00566.13 EKX72978.1 - 5.6e-54 182.8 0.5 7.6e-54 182.4 0.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ATP_bind_3 PF01171.15 EKX72979.1 - 6e-32 110.6 3.1 8.7e-20 70.9 0.0 3.2 2 1 0 2 2 2 2 PP-loop family Acatn PF13000.2 EKX72980.1 - 7.9e-58 196.3 17.3 3.9e-48 164.3 4.8 2.1 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 RRM_6 PF14259.1 EKX72981.1 - 0.0013 18.6 0.0 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX72981.1 - 0.0047 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CinA PF02464.12 EKX72981.1 - 0.0048 16.3 0.8 0.0082 15.6 0.6 1.3 1 0 0 1 1 1 1 Competence-damaged protein RRM_1 PF00076.17 EKX72981.1 - 0.037 13.6 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chordopox_E11 PF06138.7 EKX72982.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus E11 protein ATP_bind_1 PF03029.12 EKX72983.1 - 1.1e-58 198.6 0.0 2e-43 148.6 0.0 2.9 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EKX72983.1 - 6.4e-05 23.7 0.0 0.00017 22.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKX72983.1 - 0.00032 21.0 0.0 0.00056 20.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EKX72983.1 - 0.002 17.6 0.0 0.0022 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain PhoH PF02562.11 EKX72983.1 - 0.002 17.3 0.0 0.28 10.3 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.1 EKX72983.1 - 0.012 15.7 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EKX72983.1 - 0.018 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EKX72983.1 - 0.035 13.8 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EKX72983.1 - 0.037 13.8 0.0 0.072 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EKX72983.1 - 0.063 13.0 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 EKX72983.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EKX72983.1 - 0.18 10.6 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4598 PF15370.1 EKX72984.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) Sipho_Gp157 PF05565.6 EKX72984.1 - 0.33 10.5 1.9 8 6.0 0.4 2.2 2 0 0 2 2 2 0 Siphovirus Gp157 DEAD PF00270.24 EKX72985.1 - 1.2e-13 50.9 0.0 2.2e-11 43.5 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EKX72985.1 - 2.8e-09 36.7 0.1 2e-08 33.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ECH PF00378.15 EKX72986.1 - 0.00046 19.3 0.0 0.0011 18.1 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EKX72986.1 - 0.05 13.7 0.1 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region GRASP55_65 PF04495.9 EKX72987.1 - 3.7e-49 166.2 0.0 2.9e-39 134.2 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EKX72987.1 - 3.5e-09 36.4 0.0 0.00052 19.8 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.19 EKX72987.1 - 0.033 14.3 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Cons_hypoth95 PF03602.10 EKX72990.1 - 3.1e-35 121.2 0.0 5.4e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EKX72990.1 - 1.6e-10 41.0 0.0 2.7e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKX72990.1 - 1.9e-07 30.7 0.0 2.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKX72990.1 - 9.2e-06 25.1 0.0 1.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 EKX72990.1 - 3e-05 23.6 0.0 4.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 EKX72990.1 - 0.00018 22.0 0.0 0.00033 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EKX72990.1 - 0.0012 18.4 0.1 0.0034 16.9 0.0 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.1 EKX72990.1 - 0.0028 17.9 0.0 0.0067 16.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 EKX72990.1 - 0.023 13.8 0.0 0.078 12.0 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MethyltransfD12 PF02086.10 EKX72990.1 - 0.048 13.1 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase DNA_methylase PF00145.12 EKX72990.1 - 0.069 12.2 0.3 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase Mannosyl_trans2 PF04188.8 EKX72991.1 - 1.5e-20 73.5 30.0 3.7e-18 65.6 17.2 2.7 2 1 0 2 2 2 2 Mannosyltransferase (PIG-V)) Nop14 PF04147.7 EKX72992.1 - 2.1e-05 22.7 15.1 2.1e-05 22.7 10.5 2.3 2 0 0 2 2 2 1 Nop14-like family CDC45 PF02724.9 EKX72992.1 - 0.00023 19.3 13.0 0.00039 18.5 9.0 1.3 1 0 0 1 1 1 1 CDC45-like protein Daxx PF03344.10 EKX72992.1 - 0.002 16.7 17.1 0.0031 16.1 11.8 1.2 1 0 0 1 1 1 1 Daxx Family CobT PF06213.7 EKX72992.1 - 0.07 12.2 21.6 0.13 11.3 15.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.6 EKX72992.1 - 0.076 11.1 17.5 0.067 11.3 10.8 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.8 EKX72992.1 - 0.38 8.4 37.5 0.26 9.0 0.0 2.6 2 0 0 2 2 2 0 DNA polymerase phi SDA1 PF05285.7 EKX72992.1 - 0.49 9.6 25.8 0.93 8.7 17.9 1.4 1 0 0 1 1 1 0 SDA1 RP-C_C PF11800.3 EKX72992.1 - 0.49 10.0 4.8 1.5 8.4 3.3 1.8 1 0 0 1 1 1 0 Replication protein C C-terminal region Astro_capsid PF03115.9 EKX72992.1 - 1.7 6.7 5.9 2.5 6.2 4.1 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor TFIIA PF03153.8 EKX72992.1 - 3 7.6 21.6 4.7 7.0 15.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 EKX72992.1 - 3.8 6.8 25.8 7.6 5.8 17.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2457 PF10446.4 EKX72992.1 - 9.2 4.8 29.7 19 3.8 20.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Guanylate_cyc PF00211.15 EKX72993.1 - 2.7e-18 65.9 0.0 1.1e-07 31.4 0.0 2.9 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain ABC_tran PF00005.22 EKX72994.1 - 3.7e-31 108.2 0.0 2.5e-17 63.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_23 PF13476.1 EKX72994.1 - 7.2e-06 26.4 1.9 0.058 13.7 0.5 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EKX72994.1 - 4.9e-05 23.0 0.1 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EKX72994.1 - 8.5e-05 22.0 1.2 0.16 11.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EKX72994.1 - 0.00011 22.2 0.1 0.1 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EKX72994.1 - 0.00013 22.0 6.9 0.02 14.8 0.1 3.7 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.1 EKX72994.1 - 0.00019 20.8 0.0 0.038 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKX72994.1 - 0.00072 19.8 0.1 0.64 10.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKX72994.1 - 0.00072 20.3 0.0 0.66 10.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EKX72994.1 - 0.00084 18.5 0.1 0.67 9.0 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family FtsK_SpoIIIE PF01580.13 EKX72994.1 - 0.001 18.5 0.1 0.77 9.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EKX72994.1 - 0.0012 17.9 1.1 0.75 8.8 0.0 2.6 3 0 0 3 3 2 2 Zeta toxin DUF258 PF03193.11 EKX72994.1 - 0.0013 17.9 0.1 0.16 11.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_membrane PF00664.18 EKX72994.1 - 0.0018 17.7 14.4 0.0018 17.7 10.0 3.3 3 0 0 3 3 3 1 ABC transporter transmembrane region DUF87 PF01935.12 EKX72994.1 - 0.0033 17.2 1.5 0.16 11.7 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 SMC_N PF02463.14 EKX72994.1 - 0.0048 16.1 0.2 0.17 11.0 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 EKX72994.1 - 0.0051 16.4 0.9 0.16 11.6 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 EKX72994.1 - 0.0061 15.3 0.3 0.018 13.8 0.0 1.8 2 0 0 2 2 2 1 ArgK protein T2SE PF00437.15 EKX72994.1 - 0.008 15.1 0.3 1.7 7.4 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 EKX72994.1 - 0.0088 15.7 0.7 1.4 8.6 0.0 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EKX72994.1 - 0.015 15.0 1.1 3.9 7.2 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EKX72994.1 - 0.02 14.5 0.5 2.2 7.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 EKX72994.1 - 0.03 14.4 0.0 14 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EKX72994.1 - 0.04 13.8 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EKX72994.1 - 0.043 14.3 0.1 17 5.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 EKX72994.1 - 0.052 13.3 0.1 3.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Dynamin family cobW PF02492.14 EKX72994.1 - 0.054 12.9 0.8 10 5.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 EKX72994.1 - 0.081 11.5 0.2 5 5.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.18 EKX72994.1 - 0.086 12.8 0.1 0.73 9.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DnaB_C PF03796.10 EKX72994.1 - 0.15 10.9 0.0 6.2 5.6 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_33 PF13671.1 EKX72994.1 - 1.6 8.6 3.2 6.6 6.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain CKS PF01111.14 EKX72996.1 - 7e-14 51.4 0.8 7e-14 51.4 0.6 1.9 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit zf-HIT PF04438.11 EKX72997.1 - 8.5e-09 34.9 11.5 1.8e-08 33.8 8.0 1.6 1 0 0 1 1 1 1 HIT zinc finger Ribosomal_S25 PF03297.10 EKX72997.1 - 0.072 13.1 0.3 0.2 11.6 0.1 1.8 1 1 0 1 1 1 0 S25 ribosomal protein Archaeal_AmoA PF12942.2 EKX72999.1 - 0.013 15.2 0.4 0.029 14.1 0.3 1.5 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) EMA PF02488.10 EKX73002.1 - 0.036 13.5 0.1 0.058 12.8 0.1 1.3 1 0 0 1 1 1 0 Merozoite Antigen Myosin_tail_1 PF01576.14 EKX73003.1 - 0.014 13.1 0.2 0.014 13.1 0.1 1.5 2 0 0 2 2 2 0 Myosin tail Mod_r PF07200.8 EKX73003.1 - 0.018 14.9 0.2 0.018 14.9 0.1 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CPG4 PF15481.1 EKX73003.1 - 0.026 14.8 1.8 0.043 14.1 0.1 2.2 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 Syntaxin PF00804.20 EKX73003.1 - 1.1 9.4 4.9 2.9 8.0 0.2 3.2 3 0 0 3 3 3 0 Syntaxin TFIIF_alpha PF05793.7 EKX73005.1 - 0.94 7.7 6.1 1.5 7.1 4.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sigma70_r1_2 PF00140.15 EKX73006.1 - 0.12 12.0 0.1 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 ABC_tran PF00005.22 EKX73007.1 - 1.6e-31 109.4 0.0 1.9e-17 63.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_23 PF13476.1 EKX73007.1 - 9.3e-06 26.1 1.9 0.057 13.7 0.5 2.4 2 0 0 2 2 2 2 AAA domain ABC_membrane PF00664.18 EKX73007.1 - 2.3e-05 23.9 24.2 2.3e-05 23.9 16.8 3.3 4 0 0 4 4 3 2 ABC transporter transmembrane region AAA_30 PF13604.1 EKX73007.1 - 4.5e-05 23.1 0.1 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EKX73007.1 - 4.9e-05 22.8 0.0 0.037 13.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EKX73007.1 - 7.8e-05 22.7 0.5 0.12 12.3 0.0 2.9 3 1 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 EKX73007.1 - 0.0001 23.0 0.1 0.68 10.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EKX73007.1 - 0.00013 21.4 2.3 0.16 11.4 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EKX73007.1 - 0.00057 20.1 0.9 0.89 9.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EKX73007.1 - 0.00072 18.6 0.2 0.72 8.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.13 EKX73007.1 - 0.00083 18.8 0.1 0.77 9.1 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_21 PF13304.1 EKX73007.1 - 0.0012 18.9 15.2 0.021 14.8 0.1 4.7 4 1 1 5 5 5 2 AAA domain DUF258 PF03193.11 EKX73007.1 - 0.0012 18.0 0.2 0.15 11.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF87 PF01935.12 EKX73007.1 - 0.0036 17.1 1.5 0.16 11.7 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 ArgK PF03308.11 EKX73007.1 - 0.005 15.6 0.3 0.018 13.8 0.0 1.9 2 0 0 2 2 2 1 ArgK protein SMC_N PF02463.14 EKX73007.1 - 0.005 16.0 0.3 0.17 11.0 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 EKX73007.1 - 0.0052 16.4 0.9 0.16 11.6 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EKX73007.1 - 0.0052 16.4 0.7 3.9 7.3 0.1 3.1 3 0 0 3 3 2 1 Part of AAA domain T2SE PF00437.15 EKX73007.1 - 0.0081 15.0 0.4 1.6 7.5 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 EKX73007.1 - 0.012 15.3 0.4 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EKX73007.1 - 0.012 15.7 0.0 12 5.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EKX73007.1 - 0.016 14.8 0.5 2.2 7.9 0.1 2.7 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.12 EKX73007.1 - 0.026 14.0 3.2 6.4 6.2 0.0 3.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Arc_PepC_II PF06847.6 EKX73007.1 - 0.035 14.5 0.1 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Miro PF08477.8 EKX73007.1 - 0.037 14.5 0.1 17 5.9 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein SbcCD_C PF13558.1 EKX73007.1 - 0.041 13.8 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 EKX73007.1 - 0.053 13.3 0.1 3.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Dynamin family cobW PF02492.14 EKX73007.1 - 0.062 12.7 1.0 10 5.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EKX73007.1 - 0.069 11.9 0.8 0.68 8.7 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain NTPase_1 PF03266.10 EKX73007.1 - 0.074 12.7 0.3 5.4 6.7 0.1 2.8 2 0 0 2 2 2 0 NTPase TrwB_AAD_bind PF10412.4 EKX73007.1 - 0.084 11.4 0.3 5 5.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.18 EKX73007.1 - 0.1 12.5 0.1 0.73 9.7 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase DnaB_C PF03796.10 EKX73007.1 - 0.13 11.0 0.0 6.2 5.6 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_33 PF13671.1 EKX73007.1 - 0.16 11.8 0.1 6.9 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EKX73007.1 - 0.37 10.2 1.2 2.4 7.5 0.0 2.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain FAINT PF04385.10 EKX73008.1 - 2.1e-15 56.3 4.8 1.3e-07 31.2 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX73008.1 - 0.0034 16.9 0.9 0.3 10.5 0.0 2.1 2 0 0 2 2 2 2 Merozoite Antigen TPR_7 PF13176.1 EKX73008.1 - 0.16 11.8 0.2 0.71 9.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat FAINT PF04385.10 EKX73009.1 - 8.3e-10 38.3 1.5 2.2e-09 37.0 1.0 1.8 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Toxin_45 PF15524.1 EKX73009.1 - 0.22 11.6 2.8 0.45 10.6 1.0 2.0 1 1 0 2 2 2 0 Putative toxin 45 polyprenyl_synt PF00348.12 EKX73010.1 - 4.4e-41 140.4 0.1 7.2e-41 139.7 0.0 1.3 1 1 0 1 1 1 1 Polyprenyl synthetase FH2 PF02181.18 EKX73014.1 - 7.3e-44 150.1 4.5 1.2e-43 149.4 3.1 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain BLOC1_2 PF10046.4 EKX73014.1 - 0.079 13.1 2.6 5.3 7.2 0.2 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UBA PF00627.26 EKX73014.1 - 0.19 11.6 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain FAINT PF04385.10 EKX73015.1 - 0.022 14.6 0.1 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73016.1 - 3.1e-10 39.7 0.0 5.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 EMA PF02488.10 EKX73016.1 - 0.041 13.3 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Merozoite Antigen Macoilin PF09726.4 EKX73016.1 - 1.2 7.3 8.2 1.1 7.4 5.7 1.1 1 0 0 1 1 1 0 Transmembrane protein MCM PF00493.18 EKX73019.1 - 1.7e-121 405.1 0.0 2.2e-121 404.6 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 EKX73019.1 - 2.2e-06 26.9 0.6 0.00058 19.0 0.0 2.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EKX73019.1 - 2.2e-06 27.4 0.0 6.3e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EKX73019.1 - 4.8e-06 26.2 0.1 6.3e-05 22.5 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EKX73019.1 - 0.021 14.2 0.0 0.08 12.4 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF2357 PF09823.4 EKX73019.1 - 0.031 13.3 0.5 1.5 7.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) MCM_N PF14551.1 EKX73019.1 - 0.085 13.3 0.0 0.34 11.3 0.0 2.1 1 0 0 1 1 1 0 MCM N-terminal domain TF_Zn_Ribbon PF08271.7 EKX73020.1 - 0.14 11.5 0.8 0.29 10.5 0.6 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Jacalin PF01419.12 EKX73022.1 - 0.043 13.7 1.3 0.061 13.2 0.1 1.9 2 0 0 2 2 2 0 Jacalin-like lectin domain DUF900 PF05990.7 EKX73023.1 - 1.6e-22 79.9 0.0 1.1e-21 77.3 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 EKX73023.1 - 0.037 13.7 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2796 PF10986.3 EKX73024.1 - 0.12 12.3 4.2 0.22 11.5 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Nucleoplasmin PF03066.10 EKX73024.1 - 0.17 11.3 8.4 0.26 10.8 5.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 EKX73024.1 - 0.62 9.8 5.2 0.96 9.2 3.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4106 PF13388.1 EKX73024.1 - 5.7 5.7 12.2 7.8 5.3 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Tubulin PF00091.20 EKX73027.1 - 2.3e-73 246.5 0.0 4.2e-73 245.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EKX73027.1 - 2.5e-43 147.1 0.4 5.3e-43 146.0 0.2 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EKX73027.1 - 9.7e-06 25.6 0.0 2.3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Mic1 PF07035.7 EKX73027.1 - 0.041 13.2 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like Tubulin_2 PF13809.1 EKX73027.1 - 0.059 12.3 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin like tRNA-synt_2b PF00587.20 EKX73030.1 - 3.4e-35 121.1 0.0 5.2e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EKX73030.1 - 8.9e-14 51.4 4.8 1.6e-13 50.6 3.3 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain TBPIP PF07106.8 EKX73030.1 - 0.0089 15.5 5.2 0.016 14.7 3.6 1.4 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3807 PF12720.2 EKX73030.1 - 0.022 14.9 3.1 0.045 13.9 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Coatomer_E PF04733.9 EKX73030.1 - 0.053 12.7 0.1 0.13 11.4 0.1 1.6 2 0 0 2 2 2 0 Coatomer epsilon subunit TMF_DNA_bd PF12329.3 EKX73030.1 - 2 8.3 9.1 3.5 7.5 1.0 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FAINT PF04385.10 EKX73031.1 - 5.9e-11 42.0 0.0 7.6e-05 22.4 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function, DUF529 DUF2812 PF11193.3 EKX73031.1 - 0.13 12.4 0.7 0.26 11.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2812) FAINT PF04385.10 EKX73032.1 - 9.3e-06 25.4 0.0 1.2e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function, DUF529 RPAP2_Rtr1 PF04181.8 EKX73033.1 - 0.04 14.0 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Rtr1/RPAP2 family FAINT PF04385.10 EKX73034.1 - 2e-33 114.0 13.7 5.3e-08 32.5 1.8 6.8 6 1 0 6 6 6 6 Domain of unknown function, DUF529 SLT_beta PF02258.11 EKX73034.1 - 0.12 12.2 0.1 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Shiga-like toxin beta subunit MFS_1 PF07690.11 EKX73035.1 - 1.4e-12 46.9 18.0 2.2e-12 46.3 12.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily RTC PF01137.16 EKX73036.1 - 6.8e-11 41.3 0.0 6.8e-05 21.7 0.0 2.1 2 0 0 2 2 2 2 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EKX73036.1 - 4.8e-06 26.5 0.1 9.5e-05 22.3 0.1 2.1 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain SUKH-4 PF14435.1 EKX73036.1 - 0.16 11.7 0.0 0.71 9.5 0.0 1.9 2 0 0 2 2 2 0 SUKH-4 immunity protein FAD_binding_2 PF00890.19 EKX73039.1 - 6.3e-122 407.4 4.1 8.5e-122 406.9 2.8 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EKX73039.1 - 9e-49 164.6 0.2 1.3e-48 164.0 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 EKX73039.1 - 5.2e-07 29.0 0.1 0.027 13.5 0.0 3.3 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.9 EKX73039.1 - 3.3e-06 27.1 0.9 5.2e-05 23.2 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKX73039.1 - 6.6e-05 21.9 0.3 0.00019 20.4 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EKX73039.1 - 0.00053 18.9 0.8 0.0019 17.1 0.8 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EKX73039.1 - 0.001 18.1 0.1 0.0016 17.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EKX73039.1 - 0.028 12.8 0.3 0.076 11.4 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein FAINT PF04385.10 EKX73040.1 - 1.6e-13 50.2 5.2 1.1e-05 25.1 0.1 4.0 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX73040.1 - 6e-12 45.9 0.0 1.1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX73040.1 - 4.5e-08 32.9 0.0 9.5e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX73040.1 - 1.1e-05 25.2 0.1 0.00065 19.4 0.0 2.5 2 0 0 2 2 2 1 Putative lysophospholipase EMA PF02488.10 EKX73040.1 - 0.00018 21.0 1.1 0.17 11.3 0.2 3.0 1 1 2 3 3 3 2 Merozoite Antigen Abhydrolase_1 PF00561.15 EKX73040.1 - 0.0016 18.0 0.1 0.049 13.1 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EKX73040.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKX73040.1 - 0.019 14.2 0.2 1.4 8.1 0.0 2.3 1 1 0 2 2 2 0 Prolyl oligopeptidase family DUF829 PF05705.9 EKX73040.1 - 0.025 14.2 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) UPF0565 PF10561.4 EKX73040.1 - 0.026 13.4 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 CPSase_L_chain PF00289.17 EKX73040.1 - 0.067 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain PAP1 PF08601.5 EKX73042.1 - 0.027 14.1 11.5 0.26 10.9 6.3 2.0 2 0 0 2 2 2 0 Transcription factor PAP1 Ribosomal_L27 PF01016.14 EKX73043.1 - 4.3e-23 80.8 1.2 4.6e-18 64.7 0.3 2.9 2 0 0 2 2 2 2 Ribosomal L27 protein Img2 PF05046.9 EKX73044.1 - 0.013 15.7 0.6 0.13 12.4 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Pyr_redox_2 PF07992.9 EKX73045.1 - 7.4e-37 127.1 3.6 4.1e-36 124.7 2.5 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EKX73045.1 - 2.8e-32 111.0 0.1 5.2e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EKX73045.1 - 1.8e-21 76.3 9.9 1.3e-17 63.9 0.5 3.9 4 1 1 5 5 5 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EKX73045.1 - 2.5e-10 39.7 4.8 1.8e-07 30.3 1.5 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EKX73045.1 - 5.3e-10 39.7 0.2 2.4e-05 24.4 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKX73045.1 - 5.6e-10 38.6 7.6 0.00015 20.8 0.1 4.0 3 1 1 4 4 4 3 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EKX73045.1 - 8.4e-10 38.2 1.9 8.9e-10 38.2 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKX73045.1 - 1e-09 37.7 5.6 5.6e-07 28.7 0.6 3.6 3 1 1 4 4 4 2 FAD binding domain HI0933_like PF03486.9 EKX73045.1 - 1.2e-09 37.1 7.8 8.4e-05 21.2 0.1 3.9 3 1 1 4 4 4 3 HI0933-like protein NAD_binding_8 PF13450.1 EKX73045.1 - 3.9e-09 36.4 1.6 9.4e-05 22.3 0.3 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EKX73045.1 - 2.8e-06 26.5 5.3 0.00011 21.3 0.2 3.1 2 1 1 3 3 3 2 Thi4 family Lycopene_cycl PF05834.7 EKX73045.1 - 0.00013 21.0 2.0 0.013 14.4 0.1 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EKX73045.1 - 0.00027 20.5 0.3 0.019 14.5 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EKX73045.1 - 0.00053 19.1 4.8 0.03 13.3 0.2 2.5 2 1 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.13 EKX73045.1 - 0.00092 18.9 2.1 0.015 14.9 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EKX73045.1 - 0.0026 17.4 0.8 0.27 10.9 0.0 2.9 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus XdhC_C PF13478.1 EKX73045.1 - 0.0045 17.3 0.0 4.3 7.6 0.0 2.4 2 0 0 2 2 2 2 XdhC Rossmann domain NAD_binding_7 PF13241.1 EKX73045.1 - 0.066 13.4 3.7 0.98 9.7 0.1 3.0 3 1 0 3 3 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 EKX73045.1 - 0.07 12.2 0.0 1.9 7.5 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAINT PF04385.10 EKX73047.1 - 3.3e-08 33.2 12.0 5.4e-05 22.9 0.2 3.0 4 1 0 4 4 4 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73048.1 - 5.7e-13 48.5 0.0 0.00018 21.2 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 EKX73048.1 - 6.2e-05 22.6 0.1 0.00025 20.5 0.0 1.9 1 1 1 2 2 2 1 Merozoite Antigen ChaB PF06150.7 EKX73048.1 - 0.12 12.1 0.3 5.1 6.9 0.0 2.4 2 0 0 2 2 2 0 ChaB FAINT PF04385.10 EKX73049.1 - 6.3e-54 179.7 31.4 8.8e-07 28.6 0.1 11.6 11 0 0 11 11 11 11 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73054.1 - 1.3e-26 92.2 0.4 2.5e-09 36.8 0.0 5.4 5 0 0 5 5 5 4 Domain of unknown function, DUF529 EMA PF02488.10 EKX73054.1 - 8.3e-09 35.2 6.3 1.7e-05 24.4 0.5 3.0 3 0 0 3 3 3 2 Merozoite Antigen RRM_1 PF00076.17 EKX73055.1 - 3.9e-20 71.2 0.0 5.7e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX73055.1 - 1.3e-14 53.9 0.0 2.1e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX73055.1 - 1.8e-13 50.1 0.0 3.2e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Skp1 PF01466.14 EKX73059.1 - 3.9e-30 103.7 0.2 5.8e-30 103.1 0.2 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EKX73059.1 - 3e-17 62.4 0.9 5.6e-17 61.5 0.6 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Peptidase_M17 PF00883.16 EKX73061.1 - 4.4e-69 232.7 1.9 7.3e-69 232.0 1.3 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Prefoldin_2 PF01920.15 EKX73064.1 - 1.3e-07 31.3 10.4 1.8e-07 30.8 6.6 1.6 1 1 1 2 2 2 1 Prefoldin subunit Sec3_C PF09763.4 EKX73064.1 - 0.0053 14.9 1.5 0.0062 14.7 1.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 MIF4G_like_2 PF09090.6 EKX73064.1 - 0.032 13.4 2.7 0.036 13.2 1.9 1.1 1 0 0 1 1 1 0 MIF4G like Seryl_tRNA_N PF02403.17 EKX73064.1 - 0.14 12.2 8.4 1.8 8.6 1.8 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.1 EKX73064.1 - 0.16 10.3 6.3 0.21 10.0 4.4 1.2 1 0 0 1 1 1 0 AAA domain FlxA PF14282.1 EKX73064.1 - 0.17 11.8 6.6 0.12 12.3 2.3 2.1 2 0 0 2 2 2 0 FlxA-like protein COG5 PF10392.4 EKX73064.1 - 0.18 11.7 3.8 0.45 10.4 1.4 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Spc7 PF08317.6 EKX73064.1 - 0.91 8.1 9.1 9.5 4.7 4.6 1.9 1 1 0 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 EKX73064.1 - 1.2 8.8 6.9 11 5.8 0.4 2.1 1 1 1 2 2 2 0 Laminin Domain II DivIC PF04977.10 EKX73064.1 - 3.8 7.0 8.9 4 6.9 2.7 2.5 1 1 0 2 2 2 0 Septum formation initiator Ribosomal_L24e PF01246.15 EKX73066.1 - 2e-28 98.0 1.7 4.3e-28 96.9 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 EKX73066.1 - 0.005 16.4 2.9 0.0095 15.5 2.0 1.5 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif FAM183 PF14886.1 EKX73066.1 - 0.075 13.5 3.1 0.16 12.4 2.2 1.6 1 0 0 1 1 1 0 FAM183A and FAM183B related UAE_UbL PF14732.1 EKX73066.1 - 0.092 12.8 0.4 0.17 12.0 0.3 1.3 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain A_deaminase_N PF08451.6 EKX73066.1 - 0.53 10.3 5.4 0.99 9.4 3.5 1.6 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal SYF2 PF08231.7 EKX73067.1 - 7.4e-38 130.0 12.6 7.4e-38 130.0 8.7 2.9 2 1 1 3 3 3 1 SYF2 splicing factor Pro_isomerase PF00160.16 EKX73067.1 - 2.7e-25 89.3 0.5 2.6e-22 79.6 0.3 2.6 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EMA PF02488.10 EKX73069.1 - 0.001 18.6 0.2 0.0013 18.2 0.1 1.1 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 EKX73069.1 - 0.0033 17.2 0.1 0.0051 16.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73070.1 - 2.9e-09 36.6 0.0 0.00075 19.2 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73071.1 - 2.3e-10 40.1 15.8 0.0027 17.5 0.1 5.0 4 1 1 5 5 5 4 Domain of unknown function, DUF529 ABC_tran PF00005.22 EKX73072.1 - 3.8e-31 108.1 0.0 3.5e-17 62.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_23 PF13476.1 EKX73072.1 - 8.5e-06 26.2 4.4 0.062 13.6 0.6 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EKX73072.1 - 1.5e-05 25.1 13.1 0.022 14.7 0.2 4.7 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.1 EKX73072.1 - 2.9e-05 24.1 0.1 0.029 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EKX73072.1 - 4.3e-05 22.9 1.1 0.085 12.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EKX73072.1 - 0.00012 21.5 0.0 0.036 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EKX73072.1 - 0.00023 20.8 0.1 0.053 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKX73072.1 - 0.00026 21.7 0.0 0.22 12.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EKX73072.1 - 0.00074 18.7 0.4 0.077 12.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EKX73072.1 - 0.00086 19.6 0.2 0.37 11.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EKX73072.1 - 0.0026 16.9 0.3 2.5 7.1 0.1 2.6 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.12 EKX73072.1 - 0.0028 17.4 2.9 0.055 13.2 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 ArgK PF03308.11 EKX73072.1 - 0.003 16.3 0.4 0.0083 14.9 0.0 1.7 2 0 0 2 2 2 1 ArgK protein FtsK_SpoIIIE PF01580.13 EKX73072.1 - 0.0031 17.0 0.3 0.79 9.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 EKX73072.1 - 0.0049 15.8 0.9 1.9 7.3 0.1 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein UPF0079 PF02367.12 EKX73072.1 - 0.0049 16.4 1.1 0.16 11.5 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EKX73072.1 - 0.006 16.2 0.6 0.8 9.4 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EKX73072.1 - 0.0072 16.4 0.1 3 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EKX73072.1 - 0.0075 15.9 1.0 2.3 7.8 0.2 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EKX73072.1 - 0.0082 15.8 1.6 4 7.2 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain SMC_N PF02463.14 EKX73072.1 - 0.0091 15.2 1.3 0.19 10.9 0.1 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Miro PF08477.8 EKX73072.1 - 0.011 16.2 0.1 4.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein DnaB_C PF03796.10 EKX73072.1 - 0.019 13.8 0.0 1 8.1 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ATP_bind_1 PF03029.12 EKX73072.1 - 0.022 14.2 0.1 8.2 5.8 0.1 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EKX73072.1 - 0.024 14.6 0.7 0.18 11.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EKX73072.1 - 0.071 12.9 0.6 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Dynamin family NB-ARC PF00931.17 EKX73072.1 - 0.079 11.7 0.1 1.1 8.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 EKX73072.1 - 0.1 12.3 0.4 5.5 6.6 0.1 2.3 2 0 0 2 2 2 0 NTPase AAA_10 PF12846.2 EKX73072.1 - 0.16 11.3 0.4 9.7 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain TrwB_AAD_bind PF10412.4 EKX73072.1 - 0.18 10.3 0.5 5.9 5.4 0.1 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.1 EKX73072.1 - 0.71 9.8 1.3 21 5.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EKX73072.1 - 1 9.2 3.2 6.6 6.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 EKX73072.1 - 2.4 7.5 7.1 6.9 6.0 0.0 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain FAINT PF04385.10 EKX73075.1 - 0.00063 19.5 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73077.1 - 1.3e-23 82.6 0.2 1.1e-05 25.1 0.0 4.8 4 1 1 5 5 5 4 Domain of unknown function, DUF529 Thioredoxin_8 PF13905.1 EKX73077.1 - 0.0059 16.6 0.0 3.7 7.7 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like BRCA-2_OB1 PF09103.5 EKX73082.1 - 0.13 11.9 0.1 12 5.6 0.0 2.3 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 RNase_PH PF01138.16 EKX73083.1 - 2.3e-19 70.0 0.0 3.4e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EKX73083.1 - 0.0085 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1012 PF06241.7 EKX73083.1 - 0.04 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1012) Aldo_ket_red PF00248.16 EKX73084.1 - 4.1e-67 225.9 0.0 6.3e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2721 PF11026.3 EKX73086.1 - 0.085 12.5 4.1 0.3 10.7 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) NIF PF03031.13 EKX73087.1 - 2.2e-22 79.4 0.7 4.5e-22 78.4 0.5 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Metallophos PF00149.23 EKX73088.1 - 1.1e-35 122.8 0.3 1.9e-35 122.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EKX73088.1 - 2.3e-18 66.0 1.3 4.5e-17 61.8 0.2 2.7 2 1 1 3 3 3 1 PPP5 TPR repeat region TPR_11 PF13414.1 EKX73088.1 - 8.6e-16 57.3 3.9 4.3e-12 45.5 0.9 2.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EKX73088.1 - 1.2e-12 46.8 3.0 0.00047 19.6 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKX73088.1 - 3e-12 45.4 0.8 0.00061 19.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat Metallophos_2 PF12850.2 EKX73088.1 - 0.0083 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPR_8 PF13181.1 EKX73088.1 - 0.11 12.2 1.3 38 4.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EKX73088.1 - 0.17 11.8 0.7 2.3 8.1 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat Phosducin PF02114.11 EKX73089.1 - 3.2e-06 26.0 0.2 3.5e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EKX73089.1 - 1.1e-05 25.0 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin EF-1_beta_acid PF10587.4 EKX73089.1 - 0.33 11.1 2.6 0.83 9.8 1.8 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Ran_BP1 PF00638.13 EKX73091.1 - 0.00012 22.0 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain CDC45 PF02724.9 EKX73091.1 - 1.3 6.9 11.7 2.3 6.1 8.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S8e PF01201.17 EKX73092.1 - 2.4e-53 179.7 0.0 2.9e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e DUF3638 PF12340.3 EKX73094.1 - 7.7e-17 61.0 0.0 2.8e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EKX73094.1 - 1.8e-14 52.5 0.1 3.8e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF946 PF06101.6 EKX73094.1 - 7.5e-05 20.9 0.0 0.00013 20.0 0.0 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) EF-hand_5 PF13202.1 EKX73094.1 - 0.0081 15.4 0.1 0.021 14.1 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EKX73094.1 - 0.01 15.9 0.3 0.046 13.8 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 EKX73094.1 - 0.029 13.6 0.2 0.097 12.0 0.1 1.9 1 0 0 1 1 1 0 EF hand Cpn60_TCP1 PF00118.19 EKX73095.1 - 4.9e-151 503.6 0.9 5.7e-151 503.4 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ATP12 PF07542.6 EKX73096.1 - 3.5e-15 56.0 0.0 5.3e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein SIS PF01380.17 EKX73097.1 - 3.7e-33 113.9 0.1 7.4e-16 57.9 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 EKX73097.1 - 1.4e-14 54.2 0.0 2.4e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EKX73097.1 - 2e-13 49.7 0.4 8.1e-10 37.9 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 EKX73097.1 - 7.4e-06 25.7 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EKX73097.1 - 0.00081 18.1 0.1 0.0016 17.1 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II RPAP1_N PF08621.5 EKX73097.1 - 0.16 11.6 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal EF-hand_4 PF12763.2 EKX73098.1 - 6.4e-22 77.2 0.4 9.6e-11 41.3 0.0 3.8 4 0 0 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EKX73098.1 - 2.2e-08 32.7 0.3 0.0052 15.9 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EKX73098.1 - 5.9e-08 32.7 6.8 0.0001 22.3 0.9 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EKX73098.1 - 1.7e-05 23.9 0.4 0.31 10.4 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EKX73098.1 - 0.00031 20.3 4.3 0.032 13.8 0.1 3.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EKX73098.1 - 0.00058 19.5 0.2 1.7 8.7 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain WEMBL PF05701.6 EKX73098.1 - 0.35 9.2 25.4 1.6 7.1 17.5 1.7 1 1 0 1 1 1 0 Weak chloroplast movement under blue light IncA PF04156.9 EKX73098.1 - 3.3 7.2 21.7 0.044 13.3 5.2 2.3 1 1 1 2 2 2 0 IncA protein SPARC_Ca_bdg PF10591.4 EKX73098.1 - 4.5 7.3 13.1 0.29 11.1 0.1 3.8 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region RRM_1 PF00076.17 EKX73099.1 - 4e-44 148.0 3.7 8.6e-18 63.7 0.1 5.7 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX73099.1 - 1.1e-38 131.0 4.1 4.1e-15 55.5 0.0 5.4 4 1 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX73099.1 - 4.3e-20 71.3 3.2 2.5e-07 30.4 0.0 5.5 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Reoviridae_Vp9 PF08978.5 EKX73101.1 - 0.12 11.2 3.2 0.15 11.0 2.2 1.1 1 0 0 1 1 1 0 Reoviridae VP9 DUF1932 PF09130.6 EKX73101.1 - 0.16 11.6 1.2 0.51 10.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) Cgr1 PF03879.9 EKX73101.1 - 0.21 11.7 25.1 0.48 10.6 17.4 1.5 1 1 0 1 1 1 0 Cgr1 family DUF2833 PF11090.3 EKX73101.1 - 0.31 11.2 2.9 1.7 8.8 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2833) FTCD_C PF04961.7 EKX73101.1 - 0.47 9.8 4.8 0.6 9.5 3.3 1.1 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Sec10 PF07393.6 EKX73101.1 - 0.51 8.4 8.0 0.61 8.1 5.6 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 DUF2072 PF09845.4 EKX73101.1 - 0.61 10.0 8.9 0.91 9.4 6.0 1.5 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DUF972 PF06156.8 EKX73101.1 - 1.2 9.5 8.1 1.9 8.8 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Relaxase PF03432.9 EKX73101.1 - 1.4 8.2 10.5 1.9 7.8 7.3 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain TMPIT PF07851.8 EKX73101.1 - 1.4 7.9 6.8 1.9 7.4 4.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3987 PF13148.1 EKX73101.1 - 2.2 6.7 8.2 2.4 6.6 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF948 PF06103.6 EKX73101.1 - 2.2 8.1 6.0 0.71 9.7 0.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.8 EKX73101.1 - 3.2 8.1 6.2 2.8 8.3 2.7 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF106 PF01956.11 EKX73101.1 - 8.1 5.9 10.8 14 5.1 7.5 1.4 1 1 0 1 1 1 0 Integral membrane protein DUF106 DER1 PF04511.10 EKX73103.1 - 7.4e-30 103.9 16.3 1.1e-29 103.3 11.3 1.2 1 0 0 1 1 1 1 Der1-like family FAST_1 PF06743.10 EKX73104.1 - 2.8e-07 30.1 0.6 1.2e-05 24.9 0.0 3.4 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 1 FAINT PF04385.10 EKX73105.1 - 2.6e-34 116.8 9.3 4.8e-09 35.9 0.3 7.2 6 1 0 6 6 6 6 Domain of unknown function, DUF529 Rad9_Rad53_bind PF08605.5 EKX73106.1 - 0.038 13.7 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding BCNT PF07572.7 EKX73109.1 - 1.9e-12 46.9 3.3 1.9e-12 46.9 2.3 2.5 3 1 0 3 3 3 1 Bucentaur or craniofacial development Polyketide_cyc PF03364.15 EKX73112.1 - 3.6e-13 49.6 0.0 4.5e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EKX73112.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DEAD PF00270.24 EKX73113.1 - 4.5e-42 143.4 0.0 6e-41 139.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKX73113.1 - 6.4e-25 86.8 0.0 1.4e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKX73113.1 - 0.00017 21.4 0.0 0.00047 20.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EKX73113.1 - 0.0039 16.2 0.0 0.0083 15.2 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EKX73113.1 - 0.012 15.4 0.1 2.5 7.9 0.1 2.9 3 0 0 3 3 3 0 Part of AAA domain Helicase_C_2 PF13307.1 EKX73113.1 - 0.049 13.5 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain Spt5-NGN PF03439.8 EKX73114.1 - 4.7e-22 77.5 0.0 1e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EKX73114.1 - 3e-13 50.1 12.1 3e-13 50.1 8.4 1.9 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EKX73114.1 - 6.2e-08 32.0 22.9 0.0012 18.4 0.2 7.8 8 0 0 8 8 8 3 KOW motif YajC PF02699.10 EKX73114.1 - 0.69 9.6 10.8 9.5 5.9 0.3 4.7 4 1 1 5 5 5 0 Preprotein translocase subunit NIF PF03031.13 EKX73116.1 - 8.8e-21 74.2 6.8 1.1e-20 73.9 1.9 2.8 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EKX73116.1 - 0.00022 21.4 0.1 0.00049 20.3 0.1 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase BRCT PF00533.21 EKX73116.1 - 0.037 14.1 0.1 0.15 12.2 0.1 2.1 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EKX73116.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain AP2 PF00847.15 EKX73117.1 - 1.8e-05 24.8 1.0 3.7e-05 23.7 0.7 1.6 1 0 0 1 1 1 1 AP2 domain SAP18 PF06487.7 EKX73118.1 - 3e-15 56.0 1.3 7.1e-15 54.8 0.1 2.3 2 1 1 3 3 3 1 Sin3 associated polypeptide p18 (SAP18) Sld5 PF05916.6 EKX73119.1 - 2.4e-12 47.0 0.3 6.1e-10 39.3 0.0 2.6 2 0 0 2 2 2 2 GINS complex protein Ribosomal_S8e PF01201.17 EKX73120.1 - 2.3e-31 108.6 1.6 3.9e-31 107.9 1.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3959 PF13105.1 EKX73120.1 - 3.1 7.0 11.4 0.086 12.1 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3959) Spo12 PF05032.7 EKX73120.1 - 5.4 6.7 5.5 1.2 8.8 0.9 2.2 2 0 0 2 2 2 0 Spo12 family DUF1604 PF07713.8 EKX73121.1 - 4.5e-10 39.1 0.9 1e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) DUF4230 PF14014.1 EKX73121.1 - 0.029 14.2 2.4 0.21 11.4 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4230) DUF2800 PF10926.3 EKX73121.1 - 0.042 12.9 1.1 0.077 12.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) DUF1754 PF08555.5 EKX73122.1 - 7.3e-14 52.1 1.5 1.3e-13 51.3 1.1 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DUF1542 PF07564.6 EKX73122.1 - 0.018 15.0 0.6 0.018 15.0 0.4 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) LIN37 PF15306.1 EKX73122.1 - 0.023 14.6 2.1 0.028 14.4 1.5 1.1 1 0 0 1 1 1 0 LIN37 ZapA PF05164.8 EKX73122.1 - 0.091 12.7 1.1 0.13 12.2 0.8 1.2 1 0 0 1 1 1 0 Cell division protein ZapA RRF_GI PF12614.3 EKX73122.1 - 0.1 12.4 0.8 0.2 11.4 0.6 1.5 1 1 0 1 1 1 0 Ribosome recycling factor GvpL_GvpF PF06386.6 EKX73122.1 - 0.15 11.6 1.4 0.2 11.2 1.0 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF3826 PF12875.2 EKX73122.1 - 0.36 10.4 3.9 0.54 9.9 2.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3826) Ku_C PF03730.9 EKX73123.1 - 0.38 11.3 3.0 1.2 9.7 0.1 2.3 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm GTP_EFTU PF00009.22 EKX73124.1 - 7.9e-59 198.2 0.0 1.2e-58 197.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EKX73124.1 - 6.7e-30 103.1 0.0 1.4e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EKX73124.1 - 1.6e-28 98.3 0.0 3.4e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EKX73124.1 - 3e-25 87.8 0.0 7.8e-25 86.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EKX73124.1 - 1.3e-10 41.1 0.0 3.3e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 EKX73124.1 - 0.024 15.1 0.0 0.055 13.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein CbiA PF01656.18 EKX73124.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FAINT PF04385.10 EKX73126.1 - 1.5e-07 31.1 2.7 0.0019 18.0 0.5 3.0 2 1 0 2 2 2 2 Domain of unknown function, DUF529 MACPF PF01823.14 EKX73130.1 - 7.6e-26 91.1 3.6 9.4e-25 87.5 2.5 2.1 1 1 0 1 1 1 1 MAC/Perforin domain Proteasome PF00227.21 EKX73131.1 - 2.6e-58 196.4 0.0 4e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EKX73131.1 - 1.2e-10 40.5 0.8 2.3e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Bac_surface_Ag PF01103.18 EKX73132.1 - 4.8e-22 78.8 8.5 6.8e-22 78.3 5.9 1.1 1 0 0 1 1 1 1 Surface antigen CPW_WPC PF09717.5 EKX73133.1 - 4.4e-57 190.5 52.9 4.2e-14 52.9 4.3 6.2 5 1 0 5 5 5 5 Plasmodium falciparum domain of unknown function (CPW_WPC) 1-cysPrx_C PF10417.4 EKX73133.1 - 5.3 6.7 6.6 6.9 6.4 0.0 3.4 3 0 0 3 3 3 0 C-terminal domain of 1-Cys peroxiredoxin Peptidase_S24 PF00717.18 EKX73134.1 - 3.4e-12 45.8 0.1 5.6e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like M11L PF11099.3 EKX73135.1 - 0.13 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Apoptosis regulator M11L like UbiA PF01040.13 EKX73136.1 - 3.6e-29 101.7 7.0 4.9e-29 101.3 4.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family BTP PF05232.7 EKX73136.1 - 0.058 13.1 0.4 0.22 11.3 0.3 2.0 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family MACPF PF01823.14 EKX73137.1 - 3.4e-37 128.1 2.3 4.3e-37 127.8 1.6 1.1 1 0 0 1 1 1 1 MAC/Perforin domain Fil_haemagg_2 PF13332.1 EKX73137.1 - 0.24 11.1 9.7 0.14 11.9 3.8 2.0 2 0 0 2 2 2 0 Haemagluttinin repeat MACPF PF01823.14 EKX73138.1 - 7.5e-57 192.4 10.9 4.5e-30 104.9 1.8 2.5 2 1 0 2 2 2 2 MAC/Perforin domain DUF1980 PF09323.5 EKX73138.1 - 0.013 15.2 0.5 0.035 13.8 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) OHA PF14418.1 EKX73139.1 - 7.9e-24 82.9 0.0 1.8e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 OST-HTH Associated domain OST-HTH PF12872.2 EKX73139.1 - 8.7e-05 22.2 0.3 0.00025 20.8 0.2 1.7 1 0 0 1 1 1 1 OST-HTH/LOTUS domain MMR_HSR1 PF01926.18 EKX73140.1 - 4.8e-20 71.6 0.0 1.3e-19 70.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP1_OBG PF01018.17 EKX73140.1 - 7.2e-18 64.7 3.4 8e-17 61.3 2.4 2.0 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.13 EKX73140.1 - 1.7e-14 53.4 0.0 2.7e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EKX73140.1 - 7.8e-06 25.4 0.0 0.00043 19.7 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EKX73140.1 - 6.5e-05 22.2 0.0 9.7e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EKX73140.1 - 0.00052 19.2 0.0 0.00079 18.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EKX73140.1 - 0.012 16.1 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Gtr1_RagA PF04670.7 EKX73140.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ArgK PF03308.11 EKX73140.1 - 0.16 10.6 0.0 0.76 8.5 0.0 1.9 2 0 0 2 2 2 0 ArgK protein dCMP_cyt_deam_1 PF00383.17 EKX73142.1 - 1.6e-15 56.5 0.5 2.2e-15 56.1 0.3 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region gag_pre-integrs PF13976.1 EKX73142.1 - 0.071 12.7 1.0 0.13 11.8 0.7 1.4 1 0 0 1 1 1 0 GAG-pre-integrase domain Bd3614-deam PF14439.1 EKX73142.1 - 0.072 12.9 0.4 0.12 12.2 0.3 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase SPC25 PF06703.6 EKX73143.1 - 2.1e-05 24.1 0.5 2.9e-05 23.7 0.4 1.3 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) HlyIII PF03006.15 EKX73143.1 - 0.0068 15.8 1.1 0.0094 15.3 0.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related COX4_pro PF03626.9 EKX73143.1 - 0.029 14.4 0.7 0.041 13.9 0.5 1.3 1 0 0 1 1 1 0 Prokaryotic Cytochrome C oxidase subunit IV Methyltransf_3 PF01596.12 EKX73143.1 - 0.1 11.6 0.2 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 O-methyltransferase Snf7 PF03357.16 EKX73144.1 - 2.2e-15 56.4 3.0 2.9e-15 56.0 2.1 1.1 1 0 0 1 1 1 1 Snf7 DUF655 PF04919.7 EKX73144.1 - 0.023 14.4 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF655) DEAD PF00270.24 EKX73145.1 - 7.2e-31 106.9 0.0 3.5e-30 104.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKX73145.1 - 6.4e-15 54.7 0.0 2.1e-14 53.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain POP1 PF06978.6 EKX73146.1 - 8.5e-42 142.9 20.2 3e-24 85.7 6.1 2.2 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EKX73146.1 - 1.6e-20 72.7 0.0 4.3e-20 71.3 0.0 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain Hist_deacetyl PF00850.14 EKX73147.1 - 2.6e-96 322.5 0.0 3.5e-96 322.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain IPK PF03770.11 EKX73147.1 - 9.5e-39 133.0 0.4 1.8e-38 132.2 0.3 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase RTP801_C PF07809.6 EKX73147.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 RTP801 C-terminal region eIF-3_zeta PF05091.7 EKX73148.1 - 7.2e-179 595.7 10.6 8.2e-179 595.5 7.3 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Selenoprotein_S PF06936.6 EKX73148.1 - 0.17 11.4 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Selenoprotein S (SelS) Patatin PF01734.17 EKX73149.1 - 4.5e-30 105.1 0.0 9.6e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase zf-HC5HC2H_2 PF13832.1 EKX73150.1 - 4.4e-16 58.8 23.7 4.9e-10 39.3 4.6 5.6 7 0 0 7 7 7 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EKX73150.1 - 9.5e-14 51.3 20.7 7.6e-09 35.5 3.6 6.0 5 1 1 6 6 6 3 PHD-like zinc-binding domain PHD PF00628.24 EKX73150.1 - 1.1e-05 25.0 10.4 1.1e-05 25.0 7.2 8.4 8 2 1 9 9 9 4 PHD-finger Rhomboid PF01694.17 EKX73151.1 - 2.8e-24 85.8 13.1 5.6e-16 58.8 1.6 3.0 1 1 2 3 3 3 2 Rhomboid family Ribosomal_L15e PF00827.12 EKX73153.1 - 4.7e-95 316.5 9.1 5.4e-95 316.3 6.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 Clat_adaptor_s PF01217.15 EKX73154.1 - 5.2e-16 58.6 0.5 6.8e-16 58.2 0.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CHASE4 PF05228.8 EKX73154.1 - 0.092 12.3 0.1 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 CHASE4 domain dNK PF01712.14 EKX73154.1 - 0.099 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase AP2 PF00847.15 EKX73155.1 - 6.7e-14 51.7 1.0 1.5e-13 50.6 0.7 1.6 1 0 0 1 1 1 1 AP2 domain DAO PF01266.19 EKX73156.1 - 3.5e-17 62.3 0.0 5.1e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.10 EKX73156.1 - 1.8e-15 56.1 0.0 6e-15 54.4 0.0 1.7 1 1 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox_3 PF13738.1 EKX73156.1 - 0.003 17.6 0.0 0.97 9.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKX73156.1 - 0.031 14.3 0.0 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EKX73156.1 - 0.085 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EKX73156.1 - 0.12 12.1 0.0 14 5.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding GCFC PF07842.7 EKX73157.1 - 0.0056 16.0 0.1 0.04 13.2 0.0 2.3 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein IBB PF01749.15 EKX73157.1 - 0.011 15.8 0.5 0.047 13.8 0.3 2.1 1 0 0 1 1 1 0 Importin beta binding domain Cytomega_gL PF01801.11 EKX73158.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L Y_Y_Y PF07495.8 EKX73159.1 - 0.012 15.3 1.5 0.079 12.7 0.3 2.6 2 0 0 2 2 2 0 Y_Y_Y domain DUF4539 PF15072.1 EKX73161.1 - 2.6e-20 71.9 0.0 3.8e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) Zip PF02535.17 EKX73162.1 - 1.3e-27 96.6 3.8 1.3e-27 96.6 2.7 1.9 1 1 1 2 2 2 1 ZIP Zinc transporter NUDIX PF00293.23 EKX73163.1 - 6.9e-09 35.4 0.0 1.1e-08 34.8 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain CPSase_L_D3 PF02787.14 EKX73166.1 - 0.052 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain SpoOE-like PF09388.5 EKX73166.1 - 0.092 12.2 0.1 0.26 10.8 0.1 1.7 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein FAINT PF04385.10 EKX73168.1 - 2.9e-14 52.6 12.1 1.8e-08 34.0 0.3 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 ETRAMP PF09716.5 EKX73168.1 - 0.021 14.7 2.3 0.24 11.3 0.0 2.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Saf-Nte_pilin PF09460.5 EKX73168.1 - 0.042 13.6 1.4 7.5 6.3 0.1 2.3 2 0 0 2 2 2 0 Saf-pilin pilus formation protein Abi PF02517.11 EKX73169.1 - 3e-12 46.5 4.1 3e-12 46.5 2.8 2.8 2 1 0 2 2 2 1 CAAX protease self-immunity UBA_4 PF14555.1 EKX73170.1 - 0.056 12.9 0.1 0.22 11.0 0.0 2.1 1 0 0 1 1 1 0 UBA-like domain Lyase_1 PF00206.15 EKX73171.1 - 5.4e-39 134.2 0.0 8.1e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.6 EKX73171.1 - 4.9e-33 113.3 0.0 2.9e-32 110.9 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal Ribosomal_S9 PF00380.14 EKX73172.1 - 1.5e-24 86.5 0.0 2.6e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ras PF00071.17 EKX73173.1 - 1.4e-62 209.8 2.0 1.9e-62 209.4 1.4 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKX73173.1 - 1.1e-21 77.4 0.1 1.8e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKX73173.1 - 2.4e-17 62.7 0.3 2.8e-17 62.5 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKX73173.1 - 4.2e-06 26.0 0.4 5.4e-06 25.7 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKX73173.1 - 9.6e-06 25.1 1.3 6.4e-05 22.4 0.9 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKX73173.1 - 1.3e-05 24.5 0.7 4.3e-05 22.7 0.2 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKX73173.1 - 0.00014 21.7 0.5 0.00027 20.8 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EKX73173.1 - 0.00068 19.7 0.1 0.0048 17.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain PduV-EutP PF10662.4 EKX73173.1 - 0.0018 17.7 1.3 0.03 13.7 0.8 2.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EKX73173.1 - 0.0027 17.2 0.2 0.027 13.9 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EKX73173.1 - 0.005 16.8 0.0 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EKX73173.1 - 0.0064 15.9 0.5 0.33 10.3 0.1 2.1 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EKX73173.1 - 0.0066 16.1 2.3 0.13 11.8 1.6 2.0 1 1 0 1 1 1 1 Archaeal ATPase CPT PF07931.7 EKX73173.1 - 0.0078 15.8 0.0 0.014 15.0 0.0 1.3 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_5 PF07728.9 EKX73173.1 - 0.014 15.1 0.1 0.061 13.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EKX73173.1 - 0.015 14.4 0.1 0.036 13.2 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EKX73173.1 - 0.015 15.5 0.6 0.028 14.7 0.4 1.7 1 1 0 1 1 1 0 ABC transporter PRK PF00485.13 EKX73173.1 - 0.019 14.5 0.6 0.051 13.1 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Septin PF00735.13 EKX73173.1 - 0.025 13.6 0.2 0.084 11.8 0.0 1.8 2 0 0 2 2 2 0 Septin NACHT PF05729.7 EKX73173.1 - 0.043 13.4 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Methyltransf_31 PF13847.1 EKX73173.1 - 0.047 13.2 0.1 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain FeoB_N PF02421.13 EKX73173.1 - 0.069 12.4 0.6 0.76 9.0 0.4 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.1 EKX73173.1 - 0.084 12.7 0.2 0.18 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EKX73173.1 - 0.13 13.0 0.2 0.29 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 EKX73173.1 - 0.87 8.2 5.6 7 5.2 0.0 2.6 1 1 1 2 2 2 0 G-protein alpha subunit CBS PF00571.23 EKX73174.1 - 4.3e-13 48.8 0.2 0.0017 18.1 0.1 3.7 4 0 0 4 4 4 3 CBS domain DASH_Dad3 PF08656.5 EKX73176.1 - 0.013 15.1 2.1 0.013 15.1 1.5 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 Microtub_assoc PF07989.6 EKX73176.1 - 0.087 12.6 3.2 0.17 11.7 2.2 1.5 1 0 0 1 1 1 0 Microtubule associated DUF972 PF06156.8 EKX73176.1 - 0.14 12.5 1.6 0.29 11.4 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 EKX73176.1 - 4.6 6.7 7.0 6.5 6.3 2.3 2.3 2 1 0 2 2 2 0 Septum formation initiator ATLF PF07737.6 EKX73177.1 - 0.0011 18.4 1.0 0.0011 18.4 0.7 1.7 2 0 0 2 2 2 1 Anthrax toxin lethal factor, N- and C-terminal domain NUC153 PF08159.7 EKX73180.1 - 1.7e-05 24.2 1.8 1.7e-05 24.2 1.2 3.3 3 0 0 3 3 3 2 NUC153 domain Proteasom_PSMB PF10508.4 EKX73181.1 - 9.1e-11 40.6 1.5 2.4e-09 35.9 1.0 2.8 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit Reo_sigmaC PF04582.7 EKX73182.1 - 0.027 13.6 6.1 0.011 14.9 2.1 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Cpn60_TCP1 PF00118.19 EKX73183.1 - 8e-133 443.5 1.7 9.5e-133 443.3 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RF-1 PF00472.15 EKX73184.1 - 2.5e-16 59.5 2.8 3.3e-16 59.1 1.9 1.1 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 EKX73184.1 - 9.7e-05 22.4 0.8 0.00012 22.0 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein LrgB PF04172.11 EKX73185.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 LrgB-like family Vps39_1 PF10366.4 EKX73186.1 - 0.051 13.6 0.1 0.074 13.0 0.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 PetG PF02529.10 EKX73186.1 - 0.17 11.4 1.6 0.58 9.7 0.0 2.3 3 0 0 3 3 3 0 Cytochrome B6-F complex subunit 5 W2 PF02020.13 EKX73187.1 - 0.0034 17.2 4.5 0.0037 17.1 1.2 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Tom37_C PF11801.3 EKX73187.1 - 0.66 9.8 6.0 0.37 10.6 0.4 2.7 2 1 0 2 2 2 0 Tom37 C-terminal domain CBFB_NFYA PF02045.10 EKX73188.1 - 0.00039 20.8 1.1 0.00082 19.8 0.8 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DAO PF01266.19 EKX73189.1 - 7.9e-38 130.2 0.0 3e-37 128.3 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKX73189.1 - 2.8e-08 33.0 0.4 3.9e-06 25.9 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EKX73189.1 - 5.4e-05 22.4 1.3 6.8e-05 22.1 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EKX73189.1 - 0.00011 21.4 0.0 0.038 13.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EKX73189.1 - 0.00014 21.7 0.0 0.00054 19.9 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EKX73189.1 - 0.0024 16.8 0.6 0.012 14.5 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EKX73189.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EKX73189.1 - 0.03 13.4 0.0 0.07 12.2 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EKX73189.1 - 0.043 12.7 0.1 0.12 11.3 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 EKX73189.1 - 0.084 11.3 0.1 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 EKX73189.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sec63 PF02889.11 EKX73191.1 - 1.3e-155 517.3 0.1 1.4e-89 300.4 0.0 2.6 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 EKX73191.1 - 1.6e-36 125.3 0.0 4.1e-26 91.4 0.0 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EKX73191.1 - 6.8e-10 38.6 0.0 2e-07 30.7 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EKX73191.1 - 1.8e-08 34.3 0.0 4.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RNA_pol_Rpb2_6 PF00562.23 EKX73192.1 - 1.5e-112 376.2 0.3 9.5e-112 373.5 0.2 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EKX73192.1 - 2.7e-40 137.4 0.3 2.6e-24 85.3 0.1 2.3 2 0 0 2 2 2 2 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EKX73192.1 - 4.6e-28 97.2 0.0 1.4e-27 95.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EKX73192.1 - 1.4e-20 72.8 1.0 3.4e-20 71.6 0.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.9 EKX73192.1 - 1.6e-17 63.5 0.2 1.8e-16 60.1 0.1 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EKX73192.1 - 5.7e-16 58.0 0.1 5.7e-16 58.0 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EKX73192.1 - 1.7e-09 37.4 0.2 4e-09 36.2 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosom_S12_S23 PF00164.20 EKX73193.1 - 1.4e-40 137.5 1.0 1.7e-40 137.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L30 PF00327.15 EKX73194.1 - 6.3e-16 57.7 1.9 1.2e-15 56.7 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 EKX73194.1 - 1.1e-15 57.3 14.2 1.8e-15 56.6 9.8 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain CH PF00307.26 EKX73195.1 - 9e-10 38.5 1.0 9e-10 38.5 0.7 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain EB1 PF03271.12 EKX73195.1 - 7.6e-09 35.4 1.5 7.6e-09 35.4 1.0 3.2 4 0 0 4 4 4 1 EB1-like C-terminal motif SlyX PF04102.7 EKX73195.1 - 0.14 12.5 1.2 0.31 11.4 0.2 2.0 2 0 0 2 2 2 0 SlyX DUF972 PF06156.8 EKX73195.1 - 0.85 9.9 6.3 0.59 10.4 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF603 PF04645.7 EKX73195.1 - 3 7.7 9.9 0.68 9.8 2.1 2.5 2 1 1 3 3 3 0 Protein of unknown function, DUF603 IncA PF04156.9 EKX73196.1 - 9.7e-05 22.0 7.5 9.7e-05 22.0 5.2 1.7 2 0 0 2 2 2 1 IncA protein TMF_DNA_bd PF12329.3 EKX73196.1 - 0.00019 21.1 7.2 0.00019 21.1 5.0 2.9 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 EKX73196.1 - 0.001 18.7 5.7 0.0018 17.9 3.2 1.7 2 0 0 2 2 2 1 Mnd1 family ATG16 PF08614.6 EKX73196.1 - 0.0022 17.8 5.0 0.0022 17.8 3.5 2.3 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF342 PF03961.8 EKX73196.1 - 0.0025 16.3 3.1 0.0035 15.8 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Sec34 PF04136.10 EKX73196.1 - 0.0026 17.4 3.3 0.0026 17.4 2.3 1.6 2 0 0 2 2 1 1 Sec34-like family DUF4201 PF13870.1 EKX73196.1 - 0.0048 16.3 8.7 0.09 12.2 5.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) PAH PF02671.16 EKX73196.1 - 0.0052 16.3 0.2 0.0052 16.3 0.1 2.2 2 0 0 2 2 2 1 Paired amphipathic helix repeat DUF2353 PF09789.4 EKX73196.1 - 0.0065 15.7 4.1 0.011 14.9 2.9 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Katanin_con80 PF13925.1 EKX73196.1 - 0.007 16.1 2.1 0.026 14.2 0.6 2.0 2 0 0 2 2 2 1 con80 domain of Katanin Filament PF00038.16 EKX73196.1 - 0.0081 15.6 6.1 0.045 13.2 3.9 2.0 2 0 0 2 2 2 1 Intermediate filament protein Scaffolding_pro PF11418.3 EKX73196.1 - 0.0081 16.4 4.8 0.0085 16.3 1.6 2.0 2 1 0 2 2 2 1 Phi29 scaffolding protein EzrA PF06160.7 EKX73196.1 - 0.015 13.5 7.3 0.0076 14.4 3.5 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA FliJ PF02050.11 EKX73196.1 - 0.022 14.8 7.9 0.14 12.1 4.2 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Mt_ATP-synt_D PF05873.7 EKX73196.1 - 0.029 13.9 0.1 0.057 13.0 0.1 1.5 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1395 PF07160.7 EKX73196.1 - 0.039 13.4 3.4 0.063 12.7 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) HlyD PF00529.15 EKX73196.1 - 0.054 12.7 2.8 0.74 9.0 2.9 1.8 2 0 0 2 2 2 0 HlyD family secretion protein Spc7 PF08317.6 EKX73196.1 - 0.078 11.6 10.9 0.21 10.2 6.1 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein Mating_N PF12731.2 EKX73196.1 - 0.08 12.8 7.0 1.8 8.4 0.1 3.5 2 1 1 3 3 3 0 Mating-type protein beta 1 GAS PF13851.1 EKX73196.1 - 0.085 12.0 8.4 0.19 10.9 4.7 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 EKX73196.1 - 0.099 12.4 9.1 0.16 11.8 5.6 1.9 2 1 0 2 2 1 0 Tropomyosin like V_ATPase_I PF01496.14 EKX73196.1 - 0.1 10.4 2.8 0.11 10.2 1.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DASH_Spc34 PF08657.5 EKX73196.1 - 0.1 12.2 7.0 0.049 13.2 3.1 1.7 1 1 1 2 2 2 0 DASH complex subunit Spc34 TMF_TATA_bd PF12325.3 EKX73196.1 - 0.11 12.1 10.1 0.29 10.8 5.9 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 EKX73196.1 - 0.16 11.1 1.3 0.23 10.6 0.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1843 PF08898.5 EKX73196.1 - 0.17 11.9 4.9 2.3 8.3 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF3450 PF11932.3 EKX73196.1 - 0.2 10.8 6.1 0.66 9.2 3.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ADIP PF11559.3 EKX73196.1 - 0.23 11.3 11.7 0.054 13.4 5.7 1.7 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding DUF3137 PF11335.3 EKX73196.1 - 0.34 10.5 3.8 1.2 8.7 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3137) DUF1192 PF06698.6 EKX73196.1 - 0.44 10.3 4.7 4.7 7.1 0.3 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) APG6 PF04111.7 EKX73196.1 - 0.54 9.2 8.0 0.4 9.6 4.6 1.4 2 0 0 2 2 1 0 Autophagy protein Apg6 Tnp_P_element PF12017.3 EKX73196.1 - 0.73 9.0 7.2 0.61 9.2 0.5 2.3 1 1 1 2 2 2 0 Transposase protein Striatin PF08232.7 EKX73196.1 - 0.74 10.1 7.7 20 5.4 5.4 2.2 1 1 0 1 1 1 0 Striatin family CENP-Q PF13094.1 EKX73196.1 - 0.94 9.4 11.6 0.7 9.8 6.5 1.9 2 1 0 2 2 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.7 EKX73196.1 - 1.1 9.0 5.7 7.5 6.3 1.4 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) DivIC PF04977.10 EKX73196.1 - 1.8 8.1 9.3 1.7 8.1 3.4 2.8 2 1 1 3 3 3 0 Septum formation initiator TPR_MLP1_2 PF07926.7 EKX73196.1 - 2 8.1 11.3 0.69 9.6 3.8 2.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 EKX73196.1 - 2.3 7.0 8.3 3 6.6 5.0 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 EKX73196.1 - 2.3 8.5 8.6 1.6 9.1 4.2 2.0 2 1 0 2 2 1 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 EKX73196.1 - 2.6 8.1 5.9 17 5.5 0.4 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 EKX73196.1 - 4.7 7.0 12.9 7.3 6.4 7.4 2.2 2 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.6 EKX73196.1 - 4.7 6.9 10.5 13 5.5 0.4 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Syntaxin PF00804.20 EKX73196.1 - 4.8 7.4 10.5 3.3 7.9 5.6 2.1 2 1 0 2 2 1 0 Syntaxin KLRAQ PF10205.4 EKX73196.1 - 5.6 7.0 9.4 2.5 8.2 4.3 1.9 2 1 0 2 2 1 0 Predicted coiled-coil domain-containing protein Prefoldin PF02996.12 EKX73196.1 - 5.8 6.5 10.2 11 5.6 0.4 2.7 2 1 1 3 3 3 0 Prefoldin subunit bZIP_1 PF00170.16 EKX73196.1 - 6.6 6.7 9.7 0.95 9.4 1.4 2.7 3 0 0 3 3 2 0 bZIP transcription factor Atracotoxin PF05353.6 EKX73198.1 - 0.044 13.6 1.9 0.15 11.9 1.3 1.9 1 0 0 1 1 1 0 Delta Atracotoxin DUF2583 PF10762.4 EKX73198.1 - 1.4 9.1 7.5 2.3 8.3 1.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) FAINT PF04385.10 EKX73199.1 - 1.7e-18 66.1 22.2 1.9e-09 37.2 0.8 5.6 6 1 0 6 6 6 3 Domain of unknown function, DUF529 Hydrolase_4 PF12146.3 EKX73199.1 - 7.7e-09 35.2 0.1 6.7e-07 29.0 0.0 2.5 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EKX73199.1 - 8.1e-07 28.9 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKX73199.1 - 1.7e-05 24.8 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EKX73199.1 - 0.032 13.5 0.0 0.068 12.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) RRM_6 PF14259.1 EKX73200.1 - 5e-09 36.0 0.1 1.7e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKX73200.1 - 5.3e-06 25.9 0.1 5.8e-05 22.6 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YajC PF02699.10 EKX73200.1 - 0.0027 17.3 0.9 0.0077 15.8 0.6 1.8 1 0 0 1 1 1 1 Preprotein translocase subunit zf-Tim10_DDP PF02953.10 EKX73201.1 - 2.5e-14 52.3 1.2 3.1e-14 52.0 0.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger MPC PF03650.8 EKX73202.1 - 6.2e-29 100.3 0.1 7.8e-29 100.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) WD40 PF00400.27 EKX73203.1 - 3.3e-61 201.1 23.0 1.7e-10 40.3 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EKX73203.1 - 6.5e-06 25.5 1.6 0.0085 15.5 0.1 3.1 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EKX73203.1 - 7.2e-05 20.8 0.3 0.00062 17.7 0.2 2.1 1 1 0 1 1 1 1 IKI3 family zf-C2H2 PF00096.21 EKX73204.1 - 2.2e-20 71.6 28.7 1.3e-05 25.2 2.4 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKX73204.1 - 3.1e-15 55.3 24.0 0.00045 20.3 1.8 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKX73204.1 - 1.9e-13 49.9 32.6 6.3e-05 23.0 3.5 5.9 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.1 EKX73204.1 - 3.9e-11 42.4 24.9 0.00018 21.2 1.1 5.2 5 1 0 5 5 5 4 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 EKX73204.1 - 0.0057 16.5 21.2 0.3 11.0 0.2 5.0 4 1 0 4 4 4 1 Zinc ribbon domain zf-C2HC_2 PF13913.1 EKX73204.1 - 0.0076 15.8 12.4 0.45 10.2 0.7 4.6 4 0 0 4 4 4 1 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EKX73204.1 - 0.0091 16.1 17.0 0.25 11.5 3.2 4.1 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EKX73204.1 - 0.0099 16.0 1.8 0.0099 16.0 1.3 4.4 5 2 0 5 5 3 1 C2H2-type zinc-finger domain HAUS5 PF14817.1 EKX73204.1 - 0.012 14.2 1.1 0.015 13.8 0.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 XPA_N PF01286.13 EKX73204.1 - 0.013 15.1 6.5 4.7 6.9 0.4 3.5 3 0 0 3 3 3 0 XPA protein N-terminal zf-C2H2_jaz PF12171.3 EKX73204.1 - 0.016 15.3 16.3 0.52 10.5 0.8 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding C1_1 PF00130.17 EKX73204.1 - 0.016 14.9 8.9 6.6 6.5 0.0 3.6 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Marek_A PF02124.10 EKX73204.1 - 0.057 12.8 0.1 0.099 12.0 0.1 1.4 1 0 0 1 1 1 0 Marek's disease glycoprotein A zf-BED PF02892.10 EKX73204.1 - 0.068 12.9 0.9 0.068 12.9 0.6 3.6 3 1 1 4 4 3 0 BED zinc finger zf-LYAR PF08790.6 EKX73204.1 - 0.088 12.5 13.5 0.12 12.1 0.3 4.6 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger IBR PF01485.16 EKX73204.1 - 0.19 11.6 0.1 0.19 11.6 0.1 3.8 2 1 1 3 3 2 0 IBR domain Prok-RING_1 PF14446.1 EKX73204.1 - 0.41 10.4 10.7 9 6.1 0.2 4.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 zf-met PF12874.2 EKX73204.1 - 0.49 10.6 10.7 1.5 9.1 0.2 4.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Rpr2 PF04032.11 EKX73204.1 - 0.52 10.2 6.4 8.4 6.3 1.4 2.6 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain SprT-like PF10263.4 EKX73204.1 - 0.84 9.2 15.7 14 5.3 2.8 3.0 1 1 1 2 2 2 0 SprT-like family Desulfoferrod_N PF06397.7 EKX73204.1 - 1.4 8.4 8.8 5.4 6.4 0.2 3.2 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain HNH PF01844.18 EKX73204.1 - 5.2 7.0 8.7 20 5.1 0.1 3.9 4 0 0 4 4 4 0 HNH endonuclease Rep_fac-A_C PF08646.5 EKX73204.1 - 5.4 6.7 15.6 1.2 8.8 0.5 3.4 3 2 0 3 3 3 0 Replication factor-A C terminal domain Mut7-C PF01927.11 EKX73204.1 - 5.6 6.9 13.9 11 5.9 0.1 3.4 1 1 2 3 3 3 0 Mut7-C RNAse domain C1_4 PF07975.7 EKX73204.1 - 5.9 6.9 21.9 7.1 6.7 1.8 4.1 2 2 2 4 4 4 0 TFIIH C1-like domain CpXC PF14353.1 EKX73204.1 - 9.7 6.1 14.5 1.4 8.9 0.4 3.5 2 2 1 3 3 3 0 CpXC protein LSM PF01423.17 EKX73205.1 - 1.4e-17 62.9 0.0 1.8e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Mago-bind PF09282.5 EKX73206.1 - 4e-14 51.8 0.8 8.1e-14 50.8 0.5 1.5 1 0 0 1 1 1 1 Mago binding DUF2012 PF09430.5 EKX73207.1 - 0.0001 22.1 0.3 0.00021 21.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) eIF-5_eIF-2B PF01873.12 EKX73208.1 - 3.5e-35 120.3 0.0 5.5e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EKX73208.1 - 1.4e-06 28.1 1.2 2e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Neur_chan_memb PF02932.11 EKX73208.1 - 0.17 11.7 0.1 0.24 11.2 0.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2387 PF09526.5 EKX73208.1 - 0.31 10.9 1.9 0.94 9.4 1.3 1.8 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) Ribosomal_L7Ae PF01248.21 EKX73209.1 - 1.9e-23 81.7 0.2 2.4e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.7 EKX73209.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Ribosomal_S19e PF01090.14 EKX73210.1 - 1.1e-47 160.9 0.0 1.3e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e GDI PF00996.13 EKX73211.1 - 9e-190 630.6 0.0 1e-189 630.4 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor DAO PF01266.19 EKX73211.1 - 0.034 13.0 0.0 0.49 9.2 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKX73211.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Tautomerase_3 PF14832.1 EKX73211.1 - 0.11 12.5 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme SWIRM PF04433.12 EKX73212.1 - 8.9e-27 93.0 0.0 2.1e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EKX73212.1 - 4.4e-09 36.2 0.0 1.5e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKX73212.1 - 2.2e-07 30.8 0.0 1.1e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain PPTA PF01239.17 EKX73214.1 - 2.1e-24 83.7 14.0 2e-05 23.7 0.1 5.6 5 1 1 6 6 6 4 Protein prenyltransferase alpha subunit repeat EMA PF02488.10 EKX73216.1 - 1.1e-74 251.0 14.3 1.3e-74 250.8 9.9 1.0 1 0 0 1 1 1 1 Merozoite Antigen FAINT PF04385.10 EKX73216.1 - 0.048 13.5 2.4 0.21 11.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73217.1 - 4.8e-08 32.7 11.8 0.0015 18.3 1.7 3.6 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Ribosomal_S17e PF00833.13 EKX73219.1 - 3.1e-59 198.0 0.5 3.5e-59 197.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 DUF3596 PF12167.3 EKX73219.1 - 0.031 13.8 0.1 0.053 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) Met_10 PF02475.11 EKX73220.1 - 7.6e-55 185.6 5.6 2.3e-54 184.0 3.9 1.8 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EKX73220.1 - 0.0051 16.8 0.0 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.10 EKX73220.1 - 0.036 13.5 0.3 0.12 11.7 0.1 1.9 2 1 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase SET PF00856.23 EKX73221.1 - 3e-07 30.8 0.2 1.1e-06 29.0 0.1 1.8 2 0 0 2 2 2 1 SET domain Ribosomal_L28e PF01778.12 EKX73223.1 - 5.2e-27 94.5 0.4 5.2e-27 94.5 0.3 2.1 2 1 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EKX73223.1 - 3.3e-14 52.8 2.3 6e-14 51.9 1.6 1.5 1 0 0 1 1 1 1 Mak16 protein C-terminal region PNPase PF03726.9 EKX73223.1 - 0.08 13.2 3.5 0.13 12.5 1.8 1.8 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF3523 PF12037.3 EKX73224.1 - 1.1e-104 349.2 26.3 1.5e-104 348.8 18.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.24 EKX73224.1 - 5.9e-26 91.2 0.0 1.3e-25 90.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EKX73224.1 - 2.9e-07 29.7 1.4 1.2e-06 27.7 0.0 2.6 2 2 1 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EKX73224.1 - 2.7e-05 24.3 4.6 0.0022 18.1 0.0 3.2 2 2 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EKX73224.1 - 0.00021 21.0 0.2 0.0042 16.8 0.1 2.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EKX73224.1 - 0.00027 21.7 0.0 0.00027 21.7 0.0 2.7 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKX73224.1 - 0.0016 18.4 7.9 0.0083 16.1 0.0 3.3 2 2 1 3 3 2 1 AAA ATPase domain AAA_33 PF13671.1 EKX73224.1 - 0.002 18.0 3.3 0.0045 16.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 EKX73224.1 - 0.0032 17.0 0.1 0.0093 15.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EKX73224.1 - 0.0038 17.1 0.0 0.014 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EKX73224.1 - 0.0041 17.1 0.0 0.012 15.6 0.0 1.9 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_19 PF13245.1 EKX73224.1 - 0.0058 16.3 0.0 0.074 12.8 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EKX73224.1 - 0.0061 15.9 0.0 0.034 13.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EKX73224.1 - 0.02 14.0 3.2 0.022 13.9 0.0 2.6 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EKX73224.1 - 0.021 15.1 5.5 0.023 14.9 0.0 3.4 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EKX73224.1 - 0.034 14.3 0.0 0.091 12.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EKX73224.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EKX73224.1 - 0.88 9.0 0.0 0.88 9.0 0.0 3.2 2 1 0 2 2 1 0 AAA domain Ins_P5_2-kin PF06090.7 EKX73225.1 - 4.7e-11 42.2 1.5 1.7e-09 37.1 1.0 2.1 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Pkinase PF00069.20 EKX73226.1 - 2.2e-50 171.2 0.0 4.2e-50 170.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX73226.1 - 6e-18 64.8 0.0 8e-16 57.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Rpr2 PF04032.11 EKX73227.1 - 1e-09 38.1 1.1 1.3e-09 37.8 0.7 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF4346 PF14251.1 EKX73227.1 - 0.066 12.9 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) SRP40_C PF05022.7 EKX73228.1 - 4.9e-23 81.4 1.4 4.9e-23 81.4 0.9 1.9 2 0 0 2 2 2 1 SRP40, C-terminal domain Pkinase PF00069.20 EKX73230.1 - 8.7e-13 48.0 0.3 1.3e-12 47.4 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX73230.1 - 2.1e-07 30.3 0.1 2.9e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKX73230.1 - 0.061 12.2 0.0 0.48 9.3 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Ribosomal_S15 PF00312.17 EKX73230.1 - 0.07 12.8 0.9 0.23 11.2 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S15 GTP_EFTU PF00009.22 EKX73231.1 - 1.2e-57 194.3 0.0 1.7e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EKX73231.1 - 3.5e-22 78.4 0.0 1.4e-21 76.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EKX73231.1 - 6.7e-16 58.1 4.7 1.3e-15 57.2 3.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EKX73231.1 - 5.9e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EKX73231.1 - 0.0013 19.2 0.0 0.43 11.0 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein cobW PF02492.14 EKX73231.1 - 0.035 13.5 0.0 0.083 12.3 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EKX73231.1 - 0.077 12.6 2.0 0.65 9.7 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Polyoma_lg_T_C PF06431.6 EKX73231.1 - 0.16 10.5 0.1 2.1 6.8 0.0 2.0 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus TMA7 PF09072.5 EKX73232.1 - 1.1e-12 48.2 11.1 1.5e-12 47.8 7.7 1.2 1 0 0 1 1 1 1 Translation machinery associated TMA7 Ribosomal_S3Ae PF01015.13 EKX73233.1 - 7.7e-79 263.5 0.8 9.1e-79 263.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family PA28_alpha PF02251.13 EKX73233.1 - 0.064 13.4 0.2 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit PX PF00787.19 EKX73235.1 - 9.8e-13 47.8 0.3 3.1e-12 46.2 0.2 2.0 1 0 0 1 1 1 1 PX domain PEP-utilisers_N PF05524.8 EKX73235.1 - 0.41 10.4 2.3 0.93 9.3 0.1 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal XkdW PF09636.5 EKX73235.1 - 0.59 10.0 8.1 0.44 10.4 0.2 3.4 3 1 0 3 3 3 0 XkdW protein Rootletin PF15035.1 EKX73235.1 - 0.71 9.8 15.5 11 5.9 10.7 2.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.7 EKX73235.1 - 1.2 9.5 7.2 37 4.7 1.0 4.1 3 1 1 4 4 4 0 SlyX DUF1515 PF07439.6 EKX73235.1 - 1.2 8.9 5.3 17 5.3 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF1439 PF07273.7 EKX73235.1 - 1.5 8.5 11.0 1.1 8.9 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1439) Ham1p_like PF01725.11 EKX73236.1 - 3.8e-51 173.1 0.0 4.3e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Glyco_transf_7N PF13733.1 EKX73238.1 - 0.013 14.8 0.6 0.022 14.1 0.4 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 TAF PF02969.12 EKX73239.1 - 4.7e-08 32.8 0.3 1.8e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 EKX73239.1 - 0.00011 22.2 0.0 0.00066 19.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) UBN2 PF14223.1 EKX73239.1 - 0.21 11.4 4.8 5.8 6.7 0.4 3.1 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EKX73239.1 - 0.27 10.8 7.1 4.3 6.9 1.2 2.5 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Topoisom_bac PF01131.15 EKX73240.1 - 3.6e-102 342.2 0.0 4.5e-102 341.8 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EKX73240.1 - 4e-16 58.8 0.0 8.1e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain AAA_assoc PF14363.1 EKX73240.1 - 0.13 12.3 0.2 0.56 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain associated at C-terminal with AAA RRM_1 PF00076.17 EKX73241.1 - 6.4e-44 147.4 0.9 7.9e-18 63.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX73241.1 - 1.8e-34 117.3 1.1 4.7e-12 45.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX73241.1 - 1.3e-30 105.1 0.1 2.9e-12 46.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EKX73241.1 - 5.6e-07 29.2 0.2 0.31 10.8 0.0 4.1 4 0 0 4 4 4 2 Limkain b1 DUF1866 PF08952.6 EKX73241.1 - 8.8e-05 22.0 0.0 0.015 14.8 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) Calcipressin PF04847.7 EKX73241.1 - 0.025 14.1 0.3 4 6.9 0.0 3.1 3 0 0 3 3 3 0 Calcipressin BRAP2 PF07576.7 EKX73241.1 - 0.029 13.9 0.2 3.6 7.2 0.0 3.0 3 0 0 3 3 3 0 BRCA1-associated protein 2 Nup35_RRM_2 PF14605.1 EKX73241.1 - 0.14 11.9 0.2 12 5.7 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif COX15-CtaA PF02628.10 EKX73242.1 - 0.12 11.2 2.2 2 7.1 0.2 2.1 1 1 0 2 2 2 0 Cytochrome oxidase assembly protein DUF1097 PF06496.6 EKX73242.1 - 0.13 12.0 5.3 0.13 12.0 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) DUF3273 PF11677.3 EKX73243.1 - 1.3e-102 342.5 9.3 1.5e-102 342.3 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Vps52 PF04129.7 EKX73244.1 - 1.1e-37 129.8 22.2 1.8e-37 129.0 15.4 1.3 1 0 0 1 1 1 1 Vps52 / Sac2 family V-ATPase_G PF03179.10 EKX73245.1 - 9.9e-15 54.7 6.8 1.1e-14 54.5 4.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EKX73245.1 - 5.1e-05 23.0 4.8 6.9e-05 22.6 3.4 1.2 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) DUF3552 PF12072.3 EKX73245.1 - 0.0055 15.9 4.9 0.0063 15.7 3.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF2960 PF11173.3 EKX73245.1 - 0.038 14.2 0.4 0.067 13.4 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2960) DUF3301 PF11743.3 EKX73245.1 - 0.059 12.8 0.2 0.079 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) vATP-synt_E PF01991.13 EKX73245.1 - 0.061 12.6 6.1 0.067 12.4 4.2 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit FliD_N PF02465.13 EKX73245.1 - 0.34 11.3 2.9 0.12 12.7 0.7 1.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Acetyltransf_1 PF00583.19 EKX73246.1 - 3.8e-14 52.4 0.0 6.4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKX73246.1 - 2.1e-08 34.2 0.2 3.3e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKX73246.1 - 2.5e-05 24.3 0.0 3.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKX73246.1 - 0.00037 20.1 0.0 0.00063 19.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EKX73246.1 - 0.00087 19.1 0.0 0.0032 17.3 0.0 2.0 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EKX73246.1 - 0.0048 17.0 0.0 0.006 16.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L23 PF00276.15 EKX73247.1 - 2.3e-18 65.9 0.1 2.3e-18 65.9 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 EKX73247.1 - 9.2e-07 28.8 9.8 9.2e-07 28.8 6.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Pyrophosphatase PF00719.14 EKX73247.1 - 0.078 12.4 0.2 0.22 10.9 0.1 1.9 1 1 0 1 1 1 0 Inorganic pyrophosphatase Paf1 PF03985.8 EKX73248.1 - 6.9e-14 51.4 6.5 7.4e-08 31.5 0.2 3.2 3 0 0 3 3 3 3 Paf1 DUF1461 PF07314.6 EKX73249.1 - 0.12 12.0 1.2 0.45 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Got1 PF04178.7 EKX73250.1 - 9e-23 80.6 20.9 1.3e-22 80.0 14.5 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1510 PF07423.6 EKX73251.1 - 2.7e-06 26.9 7.8 3.2e-06 26.6 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Trypan_PARP PF05887.6 EKX73251.1 - 2.9e-05 23.9 7.0 3.8e-05 23.5 4.9 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) MIP-T3 PF10243.4 EKX73251.1 - 0.0085 14.6 18.9 0.0094 14.4 13.1 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Neur_chan_memb PF02932.11 EKX73251.1 - 0.036 13.9 0.2 0.049 13.5 0.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PhrC_PhrF PF11131.3 EKX73251.1 - 0.049 13.1 2.3 0.092 12.3 1.6 1.3 1 0 0 1 1 1 0 Rap-phr extracellular signalling Herpes_US9 PF06072.6 EKX73251.1 - 0.052 13.3 0.3 0.085 12.7 0.2 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Calc_CGRP_IAPP PF00214.14 EKX73251.1 - 0.055 13.5 0.4 0.12 12.4 0.1 1.6 1 1 1 2 2 2 0 Calcitonin / CGRP / IAPP family Asp-B-Hydro_N PF05279.6 EKX73251.1 - 0.059 13.2 10.4 0.07 12.9 7.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Herpes_DNAp_acc PF04929.7 EKX73251.1 - 0.23 10.3 6.4 0.27 10.1 4.5 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Shisa PF13908.1 EKX73251.1 - 0.85 9.7 3.1 1.6 8.8 2.2 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator CDC45 PF02724.9 EKX73251.1 - 1.1 7.2 6.9 1.1 7.1 4.8 1.0 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.3 EKX73251.1 - 1.1 7.8 5.3 1.2 7.7 3.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3357 PF11837.3 EKX73251.1 - 1.9 8.3 8.4 22 4.9 5.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DUF2201_N PF13203.1 EKX73251.1 - 2 7.5 7.1 2.3 7.3 4.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Pox_Ag35 PF03286.9 EKX73251.1 - 8.4 5.8 14.5 11 5.4 10.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RCC1 PF00415.13 EKX73252.1 - 6.8e-42 141.4 3.3 1.3e-11 44.5 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EKX73252.1 - 2.3e-26 90.7 14.5 1e-07 31.3 0.8 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat DZR PF12773.2 EKX73252.1 - 0.046 13.5 4.0 0.11 12.3 2.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.13 EKX73252.1 - 0.05 12.7 8.1 0.12 11.4 5.6 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others eIF2A PF08662.6 EKX73252.1 - 0.075 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Asp PF00026.18 EKX73253.1 - 1.4e-17 63.9 2.0 4.9e-17 62.1 1.4 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EKX73253.1 - 2.6e-16 59.9 3.5 7.2e-16 58.5 2.4 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EKX73253.1 - 4.8e-07 29.4 0.0 6.3e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal UCH PF00443.24 EKX73254.1 - 5.9e-36 123.9 3.0 1.7e-35 122.4 2.1 1.9 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKX73254.1 - 1.7e-18 67.0 4.1 7e-18 65.0 2.8 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase LYTB PF02401.13 EKX73255.1 - 1.5e-95 319.3 0.3 1.7e-95 319.1 0.2 1.0 1 0 0 1 1 1 1 LytB protein DUF3228 PF11539.3 EKX73256.1 - 5.6e-82 273.6 0.1 7.7e-82 273.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) TMEM95 PF15203.1 EKX73256.1 - 0.0032 16.8 0.2 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 TMEM95 family Pyr_redox_2 PF07992.9 EKX73257.1 - 7.6e-25 87.9 0.2 1.4e-24 87.0 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKX73257.1 - 2.4e-15 56.6 0.8 1.5e-12 47.6 0.1 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EKX73257.1 - 5.3e-13 48.3 0.1 1.3e-12 47.1 0.1 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DAO PF01266.19 EKX73257.1 - 1.8e-09 36.9 0.3 0.00023 20.1 0.0 3.4 3 1 0 3 3 3 2 FAD dependent oxidoreductase Rieske_2 PF13806.1 EKX73257.1 - 8.7e-07 28.6 0.0 4.6e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.1 EKX73257.1 - 2.1e-05 24.7 0.0 0.00023 21.3 0.0 2.4 2 0 0 2 2 2 1 Reductase C-terminal Pyr_redox_3 PF13738.1 EKX73257.1 - 6.5e-05 23.0 0.0 0.0021 18.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKX73257.1 - 0.00015 20.7 0.6 13 4.5 0.0 4.0 2 2 2 4 4 4 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 EKX73257.1 - 0.0016 18.6 0.1 0.66 10.2 0.1 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding TrkA_N PF02254.13 EKX73257.1 - 0.01 15.7 0.0 4 7.4 0.0 2.9 3 1 0 3 3 3 0 TrkA-N domain NAD_binding_9 PF13454.1 EKX73257.1 - 0.017 14.9 0.1 0.22 11.2 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF1344 PF07076.6 EKX73257.1 - 0.046 13.3 1.8 0.099 12.2 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) NAD_binding_8 PF13450.1 EKX73257.1 - 0.059 13.4 0.2 2.6 8.1 0.1 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EKX73257.1 - 0.1 11.0 1.5 0.85 8.0 0.0 2.8 4 0 0 4 4 4 0 HI0933-like protein Chorein_N PF12624.2 EKX73258.1 - 1.3e-29 102.0 1.5 5.1e-29 100.2 0.2 2.7 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EKX73258.1 - 0.00049 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 ATG C terminal domain DEAD PF00270.24 EKX73259.1 - 6e-16 58.4 0.0 1.6e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EKX73259.1 - 4.2e-08 33.2 0.1 3.1e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EKX73259.1 - 0.0011 18.7 0.0 0.0031 17.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ras PF00071.17 EKX73260.1 - 9e-57 190.9 0.4 1.1e-56 190.7 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKX73260.1 - 4.7e-21 75.4 0.1 1.4e-20 73.9 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKX73260.1 - 7.6e-13 48.0 0.0 8.7e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKX73260.1 - 1.8e-07 31.1 0.0 2.6e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKX73260.1 - 6.4e-06 25.4 0.1 7.3e-06 25.2 0.1 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKX73260.1 - 3.2e-05 23.4 0.1 0.0011 18.4 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKX73260.1 - 0.0002 20.6 0.0 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EKX73260.1 - 0.0005 19.8 0.0 0.00067 19.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase Septin PF00735.13 EKX73260.1 - 0.00065 18.8 0.1 0.002 17.2 0.0 1.7 2 0 0 2 2 2 1 Septin DUF258 PF03193.11 EKX73260.1 - 0.00068 18.8 0.0 0.0014 17.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EKX73260.1 - 0.0022 17.7 0.0 0.0066 16.1 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EKX73260.1 - 0.0025 17.9 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EKX73260.1 - 0.0025 17.4 0.3 0.15 11.5 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EKX73260.1 - 0.0033 17.0 0.0 0.0077 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKX73260.1 - 0.0055 16.7 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.10 EKX73260.1 - 0.0081 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 NTPase NACHT PF05729.7 EKX73260.1 - 0.01 15.4 0.0 0.029 14.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 EKX73260.1 - 0.011 15.2 0.1 0.02 14.3 0.0 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EKX73260.1 - 0.021 14.2 0.1 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 EKX73260.1 - 0.026 13.9 0.2 0.048 13.1 0.1 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EKX73260.1 - 0.031 14.4 0.1 0.081 13.1 0.0 1.8 2 1 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 EKX73260.1 - 0.036 13.9 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKX73260.1 - 0.039 14.2 0.4 0.053 13.8 0.3 1.6 1 1 0 1 1 1 0 ABC transporter AIG1 PF04548.11 EKX73260.1 - 0.064 12.3 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 AIG1 family PRK PF00485.13 EKX73260.1 - 0.069 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 EKX73260.1 - 0.083 12.8 0.1 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EKX73260.1 - 0.089 12.0 0.2 0.31 10.2 0.0 2.0 2 1 1 3 3 3 0 Ferrous iron transport protein B G-alpha PF00503.15 EKX73260.1 - 0.11 11.1 2.6 0.25 10.0 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Rer1 PF03248.8 EKX73261.1 - 4.7e-60 202.1 8.9 6.1e-60 201.8 6.2 1.1 1 0 0 1 1 1 1 Rer1 family Cullin PF00888.17 EKX73263.1 - 8.6e-40 136.8 30.4 3.1e-39 135.0 21.1 2.0 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EKX73263.1 - 6.1e-06 25.9 0.1 6.1e-06 25.9 0.1 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain DOT1 PF08123.8 EKX73264.1 - 0.002 17.4 0.0 0.0048 16.2 0.0 1.7 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 EKX73264.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-RanBP PF00641.13 EKX73265.1 - 1.9e-06 26.8 1.8 4e-06 25.8 1.3 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Zip PF02535.17 EKX73265.1 - 2.1 7.2 7.4 3 6.7 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter zf-XS PF03470.9 EKX73266.1 - 0.046 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 XS zinc finger domain Steroid_dh PF02544.11 EKX73267.1 - 1.6e-31 109.0 15.5 1.6e-31 109.0 10.8 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF805 PF05656.9 EKX73267.1 - 0.12 12.1 9.3 0.12 12.2 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Alba PF01918.16 EKX73268.1 - 1.4e-14 53.4 0.1 2e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Alba IF3_C PF00707.17 EKX73268.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 1 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain Peptidase_U32 PF01136.14 EKX73268.1 - 0.042 12.7 0.0 0.053 12.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family U32 ATP_synt_H PF05493.8 EKX73269.1 - 5.2e-11 42.4 5.4 8.1e-11 41.8 3.8 1.3 1 1 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 EKX73269.1 - 0.0055 16.1 0.8 0.0063 15.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF4149 PF13664.1 EKX73269.1 - 0.019 15.0 3.3 0.025 14.6 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Ammonium_transp PF00909.16 EKX73269.1 - 0.023 13.1 0.3 0.026 13.0 0.2 1.0 1 0 0 1 1 1 0 Ammonium Transporter Family Arif-1 PF06770.6 EKX73269.1 - 0.07 12.4 2.3 0.081 12.2 1.6 1.0 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) O-antigen_lig PF13425.1 EKX73269.1 - 0.089 12.7 1.1 0.1 12.5 0.8 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ABC2_membrane PF01061.19 EKX73269.1 - 0.099 11.7 4.8 0.11 11.6 3.3 1.1 1 0 0 1 1 1 0 ABC-2 type transporter MNHE PF01899.11 EKX73269.1 - 0.16 11.5 1.7 0.2 11.2 1.2 1.1 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit DUF2206 PF09971.4 EKX73269.1 - 0.19 10.5 1.1 0.2 10.4 0.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) TMEM213 PF15192.1 EKX73269.1 - 0.23 11.4 0.1 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 TMEM213 family DUF4234 PF14018.1 EKX73269.1 - 0.62 9.8 4.1 1.1 9.0 2.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) YrhC PF14143.1 EKX73269.1 - 0.97 9.4 4.0 4.7 7.2 0.1 2.2 1 1 1 2 2 2 0 YrhC-like protein PIG-P PF08510.7 EKX73269.1 - 4 7.0 8.0 0.31 10.6 1.5 1.8 1 1 1 2 2 2 0 PIG-P AAA_12 PF13087.1 EKX73270.1 - 1.9e-54 184.0 0.0 9.4e-54 181.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EKX73270.1 - 6.6e-43 146.9 0.1 3.9e-42 144.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKX73270.1 - 6.5e-13 48.2 0.0 2.1e-12 46.6 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 EKX73270.1 - 4.8e-08 32.8 0.0 3.1e-07 30.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 EKX73270.1 - 3.4e-06 26.4 0.0 0.011 15.0 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.4 EKX73270.1 - 0.00047 19.2 0.2 0.031 13.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EKX73270.1 - 0.00084 18.8 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 EKX73270.1 - 0.0015 18.1 0.0 0.0073 15.9 0.0 2.2 2 0 0 2 2 2 1 NACHT domain KaiC PF06745.8 EKX73270.1 - 0.0022 17.1 0.1 1.4 7.9 0.0 2.4 2 0 0 2 2 2 2 KaiC ResIII PF04851.10 EKX73270.1 - 0.0025 17.6 0.0 0.015 15.1 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EKX73270.1 - 0.0098 16.0 0.1 0.15 12.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EKX73270.1 - 0.018 15.2 0.0 0.047 13.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EKX73270.1 - 0.021 14.3 0.0 0.11 11.9 0.0 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase Nbas_N PF15492.1 EKX73270.1 - 0.022 13.8 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal AAA_16 PF13191.1 EKX73270.1 - 0.03 14.3 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain dsrm PF00035.20 EKX73270.1 - 0.034 14.7 0.7 30 5.2 0.0 3.6 3 0 0 3 3 3 0 Double-stranded RNA binding motif AAA_25 PF13481.1 EKX73270.1 - 0.041 13.2 0.0 0.15 11.4 0.0 1.8 1 1 1 2 2 2 0 AAA domain Zot PF05707.7 EKX73270.1 - 0.044 13.2 0.2 6.9 6.0 0.0 3.7 4 0 0 4 4 4 0 Zonular occludens toxin (Zot) Ribosomal_S18 PF01084.15 EKX73271.1 - 0.0072 16.1 1.0 0.029 14.2 0.5 1.9 1 1 1 2 2 2 1 Ribosomal protein S18 HHH_7 PF14635.1 EKX73273.1 - 2.9e-19 69.1 0.1 1.3e-18 66.9 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif SH2_2 PF14633.1 EKX73273.1 - 1.8e-12 46.8 0.0 4.7e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.1 EKX73273.1 - 2.5e-10 40.3 0.9 1.4e-09 37.9 0.7 2.3 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 RRM_1 PF00076.17 EKX73274.1 - 4.5e-17 61.4 0.0 5.6e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX73274.1 - 2.4e-15 56.2 0.0 3e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX73274.1 - 6.2e-11 41.9 0.0 1.2e-10 41.0 0.0 1.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKX73274.1 - 1.6e-05 24.7 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.3 EKX73274.1 - 0.087 12.5 0.0 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 Limkain b1 NYD-SP28_assoc PF14775.1 EKX73275.1 - 0.0059 16.2 3.2 0.033 13.8 2.2 2.4 1 0 0 1 1 1 1 Sperm tail C-terminal domain DUF904 PF06005.7 EKX73275.1 - 1.3 9.3 15.7 0.37 11.1 3.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 EKX73275.1 - 1.4 8.8 15.0 0.75 9.7 3.8 2.9 2 0 0 2 2 2 0 bZIP transcription factor MOZART1 PF12554.3 EKX73276.1 - 4.2e-18 64.5 0.3 5.1e-18 64.2 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.2 EKX73276.1 - 0.0022 17.5 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SpoVIF PF14069.1 EKX73276.1 - 0.025 14.2 0.1 0.1 12.3 0.0 1.7 1 1 1 2 2 2 0 Stage VI sporulation protein F CM_2 PF01817.16 EKX73276.1 - 0.097 12.7 0.0 0.32 11.1 0.0 1.7 1 1 1 2 2 2 0 Chorismate mutase type II NPV_P10 PF05531.7 EKX73277.1 - 0.025 14.8 1.8 0.025 14.8 1.2 4.7 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Img2 PF05046.9 EKX73279.1 - 4.3e-10 39.6 0.3 9e-10 38.6 0.2 1.5 1 1 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) DctQ PF04290.7 EKX73280.1 - 0.042 13.6 0.1 0.067 12.9 0.1 1.3 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component EF-hand_7 PF13499.1 EKX73281.1 - 1.4e-27 95.6 2.6 3.4e-16 59.1 1.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EKX73281.1 - 2e-24 82.9 4.9 1.1e-07 30.6 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EKX73281.1 - 7.7e-21 72.0 2.9 1.4e-07 30.8 0.0 3.9 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EKX73281.1 - 2.4e-19 68.6 7.0 6.6e-11 41.6 0.3 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EKX73281.1 - 3.1e-15 54.7 5.6 4.7e-05 22.5 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EKX73281.1 - 5.2e-08 32.6 0.0 8.6e-06 25.5 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_4 PF12763.2 EKX73281.1 - 0.0011 18.6 0.6 0.031 14.0 0.1 2.6 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 EKX73281.1 - 0.0092 15.5 0.1 0.043 13.3 0.1 2.1 1 1 0 1 1 1 1 Caleosin related protein PMBR PF09373.5 EKX73281.1 - 0.14 12.1 0.1 15 5.7 0.0 3.8 5 0 0 5 5 5 0 Pseudomurein-binding repeat FAST_1 PF06743.10 EKX73283.1 - 0.048 13.3 0.2 19 5.0 0.0 3.4 3 1 1 4 4 4 0 FAST kinase-like protein, subdomain 1 HTH_10 PF04967.7 EKX73285.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain Ribosomal_L28e PF01778.12 EKX73286.1 - 3.8e-19 69.2 0.4 4.4e-19 68.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF1398 PF07166.6 EKX73286.1 - 0.006 16.4 0.0 0.0069 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1398) FAINT PF04385.10 EKX73287.1 - 2.2e-18 65.8 4.5 5.9e-06 26.0 0.0 4.7 4 0 0 4 4 4 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX73287.1 - 1.9e-12 47.5 0.0 4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX73287.1 - 1.9e-09 37.4 0.0 4.6e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX73287.1 - 9.6e-09 34.9 0.3 7.9e-08 32.0 0.1 2.5 2 0 0 2 2 2 1 Putative lysophospholipase EMA PF02488.10 EKX73287.1 - 3.9e-05 23.2 6.5 0.0023 17.4 0.0 2.9 2 1 0 2 2 2 2 Merozoite Antigen Abhydrolase_3 PF07859.8 EKX73287.1 - 0.083 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Kei1 PF08552.6 EKX73289.1 - 0.0043 16.7 0.1 0.011 15.4 0.1 1.8 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 ABC_tran PF00005.22 EKX73290.1 - 6.6e-32 110.6 0.0 1.8e-17 63.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_23 PF13476.1 EKX73290.1 - 1.7e-05 25.2 6.2 0.012 15.9 0.7 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EKX73290.1 - 1.9e-05 24.7 0.1 0.026 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EKX73290.1 - 0.00011 21.6 1.9 0.074 12.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.1 EKX73290.1 - 0.00025 20.6 0.2 0.12 11.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EKX73290.1 - 0.00028 20.1 0.2 0.25 10.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EKX73290.1 - 0.001 18.5 0.0 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKX73290.1 - 0.0013 19.5 0.0 0.2 12.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EKX73290.1 - 0.0015 17.3 0.3 0.0075 15.0 0.0 1.9 2 0 0 2 2 2 1 ArgK protein Zeta_toxin PF06414.7 EKX73290.1 - 0.0018 17.4 0.1 0.63 9.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_15 PF13175.1 EKX73290.1 - 0.0024 17.0 0.2 1 8.3 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain Miro PF08477.8 EKX73290.1 - 0.0045 17.4 0.0 4.3 7.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EKX73290.1 - 0.0062 16.6 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EKX73290.1 - 0.0064 16.1 0.4 0.79 9.4 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EKX73290.1 - 0.013 15.1 0.6 0.32 10.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EKX73290.1 - 0.013 15.2 1.0 4.7 7.0 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain MMR_HSR1 PF01926.18 EKX73290.1 - 0.013 15.4 0.3 0.36 10.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EKX73290.1 - 0.017 14.6 0.4 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 EKX73290.1 - 0.018 13.9 0.8 1.7 7.4 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.1 EKX73290.1 - 0.025 14.8 0.1 0.78 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EKX73290.1 - 0.038 13.4 0.1 0.28 10.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.12 EKX73290.1 - 0.042 13.6 2.1 0.14 11.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 SMC_N PF02463.14 EKX73290.1 - 0.062 12.5 1.2 0.58 9.3 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EKX73290.1 - 0.075 12.6 0.5 9.8 5.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 EKX73290.1 - 0.08 12.7 0.1 16 5.2 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_21 PF13304.1 EKX73290.1 - 0.095 12.6 0.0 0.095 12.6 0.0 4.6 6 0 0 6 6 4 0 AAA domain cobW PF02492.14 EKX73290.1 - 0.12 11.7 1.8 10 5.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 EKX73290.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit TrwB_AAD_bind PF10412.4 EKX73290.1 - 0.16 10.5 0.2 5.4 5.5 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Vasculin PF15337.1 EKX73291.1 - 0.076 13.4 2.4 0.17 12.3 0.1 2.5 3 0 0 3 3 3 0 Vascular protein family Vasculin-like 1 Tbf5 PF06331.7 EKX73293.1 - 3.8e-11 42.6 0.1 4.7e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 FAINT PF04385.10 EKX73294.1 - 6.5e-12 45.1 5.5 7.4e-06 25.7 1.2 2.8 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF4398 PF14346.1 EKX73294.1 - 0.058 13.4 4.9 1.6 8.8 3.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) COG2 PF06148.6 EKX73294.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.6 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.7 EKX73294.1 - 3.1 7.5 11.1 1.1 9.0 0.3 3.6 3 1 1 4 4 4 0 Laminin Domain II TPR_11 PF13414.1 EKX73295.1 - 0.059 13.0 0.3 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.1 EKX73295.1 - 0.94 9.4 4.0 46 4.1 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3316 PF11777.3 EKX73296.1 - 0.0026 17.5 0.1 0.0089 15.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3316) Pex14_N PF04695.8 EKX73296.1 - 0.13 12.2 0.2 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAINT PF04385.10 EKX73297.1 - 4.9e-13 48.7 6.0 2.5e-05 24.0 0.0 5.1 5 0 0 5 5 5 3 Domain of unknown function, DUF529 Hydrolase_4 PF12146.3 EKX73297.1 - 1.9e-08 34.0 0.0 8.7e-08 31.9 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EKX73297.1 - 6.4e-07 29.4 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX73297.1 - 6.4e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family FAINT PF04385.10 EKX73298.1 - 1.1e-22 79.7 24.4 0.0077 16.0 0.0 9.6 8 2 1 9 9 9 8 Domain of unknown function, DUF529 PolyA_pol PF01743.15 EKX73301.1 - 7.5e-27 94.0 0.0 1.3e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EKX73301.1 - 0.0009 18.7 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DDRGK PF09756.4 EKX73302.1 - 9.1e-46 155.6 25.6 1.3e-45 155.1 17.8 1.2 1 0 0 1 1 1 1 DDRGK domain DUF1510 PF07423.6 EKX73302.1 - 0.0064 15.8 13.8 0.011 15.1 9.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Pex24p PF06398.6 EKX73302.1 - 0.035 12.8 1.6 0.051 12.3 1.1 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin IncA PF04156.9 EKX73302.1 - 0.077 12.5 21.2 0.12 11.9 14.7 1.5 1 1 0 1 1 1 0 IncA protein Ycf1 PF05758.7 EKX73302.1 - 0.16 9.6 17.9 0.044 11.5 10.2 1.5 2 0 0 2 2 2 0 Ycf1 SID-1_RNA_chan PF13965.1 EKX73302.1 - 0.29 9.2 3.9 0.39 8.8 2.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.11 EKX73302.1 - 0.32 10.8 2.1 0.42 10.4 1.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S64 PF08192.6 EKX73302.1 - 0.54 8.5 7.1 0.7 8.1 4.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 Borrelia_P83 PF05262.6 EKX73302.1 - 0.89 7.7 20.6 1.1 7.4 14.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein V_ATPase_I PF01496.14 EKX73302.1 - 1.2 6.8 9.4 1.5 6.5 6.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CAF-1_p150 PF11600.3 EKX73302.1 - 1.2 8.4 39.6 1.8 7.8 27.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1980 PF09323.5 EKX73302.1 - 2.5 7.8 9.5 0.14 11.9 1.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) DUF4407 PF14362.1 EKX73302.1 - 2.6 6.9 10.1 3.5 6.4 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PLRV_ORF5 PF01690.12 EKX73302.1 - 4.2 6.4 12.2 4.8 6.2 8.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein RNA_pol_Rpb1_5 PF04998.12 EKX73302.1 - 5.6 6.1 7.1 6.9 5.8 4.9 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 RR_TM4-6 PF06459.7 EKX73302.1 - 5.9 6.6 22.4 8.9 6.1 15.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ETRAMP PF09716.5 EKX73302.1 - 9.2 6.2 6.4 35 4.4 4.2 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Helicase_C_2 PF13307.1 EKX73303.1 - 4.2e-28 98.4 0.0 5.2e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain FAINT PF04385.10 EKX73305.1 - 0.00045 20.0 1.7 0.00075 19.2 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function, DUF529 Dyp_perox PF04261.7 EKX73305.1 - 0.004 15.9 0.0 0.0061 15.3 0.0 1.2 1 0 0 1 1 1 1 Dyp-type peroxidase family PRELI PF04707.9 EKX73306.1 - 5.8e-21 74.6 0.2 6.9e-21 74.4 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family DUF1977 PF09320.6 EKX73306.1 - 0.03 14.5 0.7 0.042 14.1 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) Telomere_Sde2 PF13019.1 EKX73307.1 - 1.5e-15 57.2 0.2 2.3e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 Telomere stability and silencing Gcd10p PF04189.8 EKX73307.1 - 0.042 12.9 7.7 0.061 12.4 5.4 1.2 1 0 0 1 1 1 0 Gcd10p family Armet PF10208.4 EKX73308.1 - 0.0052 16.4 3.4 0.012 15.2 0.1 2.7 1 1 2 3 3 3 1 Degradation arginine-rich protein for mis-folding CFTR_R PF14396.1 EKX73308.1 - 0.028 13.7 0.9 0.043 13.1 0.6 1.2 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain BACK PF07707.10 EKX73309.1 - 0.00014 21.6 0.0 0.00063 19.5 0.0 2.1 2 1 0 2 2 2 1 BTB And C-terminal Kelch ESCRT-II PF05871.7 EKX73310.1 - 2.7e-12 46.7 0.0 8.6e-12 45.1 0.0 1.9 1 1 0 1 1 1 1 ESCRT-II complex subunit FH2 PF02181.18 EKX73310.1 - 0.039 12.8 0.1 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Prenyltrans PF00432.16 EKX73311.1 - 6.4e-38 127.9 5.8 6.6e-09 35.1 0.1 5.1 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EKX73311.1 - 2.2e-31 108.5 0.0 2.1e-15 57.0 0.0 3.7 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EKX73311.1 - 1.7e-09 37.6 0.0 1.9e-05 24.6 0.0 3.8 2 1 2 4 4 4 2 Prenyltransferase-like CDC27 PF09507.5 EKX73312.1 - 8.5e-07 28.5 41.8 1.1e-05 24.8 4.7 2.0 1 1 0 2 2 2 2 DNA polymerase subunit Cdc27 Mitofilin PF09731.4 EKX73312.1 - 4.4 5.8 23.0 6.7 5.2 15.9 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MMR_HSR1 PF01926.18 EKX73313.1 - 3.8e-47 159.0 0.6 5.7e-23 81.0 0.0 2.6 3 0 0 3 3 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.1 EKX73313.1 - 8.6e-26 89.7 0.0 2.5e-25 88.2 0.0 1.9 1 1 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.13 EKX73313.1 - 3e-23 81.8 0.1 3.3e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Miro PF08477.8 EKX73313.1 - 7.7e-20 71.5 0.2 1.3e-09 38.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 EKX73313.1 - 1.3e-18 67.0 0.3 2.2e-11 43.5 0.0 4.0 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Ras PF00071.17 EKX73313.1 - 6.6e-14 51.6 0.1 7.6e-08 31.8 0.0 2.4 2 1 0 2 2 2 2 Ras family Dynamin_N PF00350.18 EKX73313.1 - 1.4e-13 51.0 0.5 0.00088 19.1 0.0 4.4 2 2 2 4 4 4 3 Dynamin family AIG1 PF04548.11 EKX73313.1 - 3.1e-13 49.3 1.8 1.8e-06 27.2 0.2 3.2 3 1 0 3 3 3 2 AIG1 family Gtr1_RagA PF04670.7 EKX73313.1 - 1.4e-09 37.5 0.6 3.9e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKX73313.1 - 2.1e-09 36.8 0.4 0.0012 18.1 0.2 2.5 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EKX73313.1 - 1.3e-08 34.4 0.0 0.0066 15.9 0.0 2.8 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EKX73313.1 - 8.3e-07 28.3 0.2 0.014 14.6 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function, DUF258 ABC_tran PF00005.22 EKX73313.1 - 1.6e-05 25.1 0.1 0.27 11.5 0.0 2.8 2 1 0 2 2 2 2 ABC transporter Arf PF00025.16 EKX73313.1 - 7.7e-05 21.9 0.4 0.0012 18.1 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_22 PF13401.1 EKX73313.1 - 0.00049 20.2 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EKX73313.1 - 0.0024 16.7 0.0 0.34 9.7 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain ArgK PF03308.11 EKX73313.1 - 0.006 15.3 0.0 7.7 5.1 0.0 3.3 3 0 0 3 3 3 0 ArgK protein Arch_ATPase PF01637.13 EKX73313.1 - 0.01 15.5 0.6 7.2 6.2 0.0 3.2 3 2 0 3 3 2 0 Archaeal ATPase AAA_18 PF13238.1 EKX73313.1 - 0.011 15.9 0.1 0.28 11.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 EKX73313.1 - 0.013 15.6 0.0 5 7.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 EKX73313.1 - 0.02 15.0 0.0 1.7 8.8 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EKX73313.1 - 0.04 13.6 0.2 7.4 6.2 0.0 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EKX73313.1 - 0.15 12.0 0.0 21 5.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain zf-CSL PF05207.8 EKX73314.1 - 3.7e-19 67.9 3.1 5e-19 67.5 2.1 1.2 1 0 0 1 1 1 1 CSL zinc finger YGGT PF02325.12 EKX73315.1 - 1.2e-14 53.9 0.6 1.6e-14 53.5 0.4 1.2 1 0 0 1 1 1 1 YGGT family FAINT PF04385.10 EKX73316.1 - 9.1e-06 25.4 0.1 1.8e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function, DUF529 ABC_tran PF00005.22 EKX73317.1 - 4.2e-33 114.5 0.0 6e-18 65.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EKX73317.1 - 2.1e-07 31.2 0.3 0.0041 17.1 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EKX73317.1 - 2.3e-06 28.0 0.8 0.018 15.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EKX73317.1 - 7e-06 25.4 0.9 0.13 11.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EKX73317.1 - 0.00012 22.1 0.2 0.16 11.9 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EKX73317.1 - 0.00013 21.5 0.1 0.015 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EKX73317.1 - 0.00018 20.7 0.2 0.15 11.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EKX73317.1 - 0.00021 20.7 0.0 0.066 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EKX73317.1 - 0.00063 18.6 0.7 0.0051 15.6 0.1 2.1 2 0 0 2 2 2 1 ArgK protein FtsK_SpoIIIE PF01580.13 EKX73317.1 - 0.00092 18.7 0.1 0.69 9.3 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EKX73317.1 - 0.0011 18.1 0.3 0.97 8.4 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_15 PF13175.1 EKX73317.1 - 0.0013 17.8 0.6 0.79 8.7 0.1 3.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EKX73317.1 - 0.0015 19.3 0.0 0.87 10.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKX73317.1 - 0.0018 18.5 0.3 1.1 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EKX73317.1 - 0.0019 18.0 2.0 0.048 13.4 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EKX73317.1 - 0.0026 17.6 0.3 0.61 10.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.14 EKX73317.1 - 0.003 16.8 2.0 0.039 13.1 0.2 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain MobB PF03205.9 EKX73317.1 - 0.004 16.8 0.3 0.63 9.7 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EKX73317.1 - 0.0046 16.7 0.3 0.28 10.9 0.0 2.5 2 0 0 2 2 2 1 Dynamin family KAP_NTPase PF07693.9 EKX73317.1 - 0.0075 15.2 0.0 0.4 9.6 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain Fer4_NifH PF00142.13 EKX73317.1 - 0.0088 15.2 0.1 2.3 7.3 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Miro PF08477.8 EKX73317.1 - 0.02 15.3 0.1 15 6.1 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein T2SE PF00437.15 EKX73317.1 - 0.042 12.7 0.5 7.8 5.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.1 EKX73317.1 - 0.048 13.8 0.2 17 5.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.1 EKX73317.1 - 0.059 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EKX73317.1 - 0.087 13.0 0.1 14 5.9 0.0 3.1 3 0 0 3 3 2 0 RNA helicase AAA_33 PF13671.1 EKX73317.1 - 0.1 12.4 0.1 5.4 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EKX73317.1 - 0.11 11.8 0.3 14 4.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain DnaB_C PF03796.10 EKX73317.1 - 0.12 11.2 0.1 8.7 5.1 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_19 PF13245.1 EKX73317.1 - 0.14 11.9 1.4 13 5.6 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EKX73317.1 - 0.15 11.6 0.7 14 5.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EKX73317.1 - 0.16 11.5 0.7 4.7 6.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 EKX73317.1 - 0.21 10.1 2.2 8.2 4.9 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FAINT PF04385.10 EKX73318.1 - 1.5e-12 47.1 5.5 3.6e-07 29.9 0.3 2.9 2 0 0 2 2 2 2 Domain of unknown function, DUF529 SAC3_GANP PF03399.11 EKX73319.1 - 9.3e-38 129.8 7.6 1.5e-37 129.1 5.3 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Methyltransf_29 PF03141.11 EKX73319.1 - 0.046 12.0 0.1 0.07 11.4 0.1 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DEAD_2 PF06733.10 EKX73320.1 - 6.8e-37 126.5 1.6 1.5e-36 125.4 1.1 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EKX73320.1 - 2.1e-36 125.3 0.0 7.5e-36 123.5 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 EKX73320.1 - 4e-05 23.1 0.0 0.0031 17.0 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 EKX73320.1 - 0.00058 19.7 1.3 0.025 14.3 0.0 3.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DUF1947 PF09183.5 EKX73320.1 - 0.053 13.2 0.5 0.57 9.9 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1947) FAINT PF04385.10 EKX73322.1 - 2.2e-09 37.0 0.0 0.014 15.2 0.0 4.0 4 0 0 4 4 4 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX73322.1 - 3e-05 23.6 2.5 1.9 7.8 0.0 3.3 3 0 0 3 3 3 3 Merozoite Antigen HMG_box PF00505.14 EKX73322.1 - 0.37 11.1 1.6 2.6 8.4 0.5 2.7 3 0 0 3 3 3 0 HMG (high mobility group) box RVT_1 PF00078.22 EKX73323.1 - 9.8e-09 34.8 0.0 2.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IPK PF03770.11 EKX73324.1 - 1.7e-20 73.5 0.2 4.2e-20 72.2 0.2 1.7 1 1 0 1 1 1 1 Inositol polyphosphate kinase Rib_5-P_isom_A PF06026.9 EKX73325.1 - 4e-38 130.4 0.1 6.2e-38 129.8 0.1 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EKX73325.1 - 0.019 14.6 0.6 2.8 7.5 0.3 2.6 2 1 0 2 2 2 0 DeoR C terminal sensor domain Rod-binding PF10135.4 EKX73325.1 - 0.034 14.1 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Rod binding protein DUF3213 PF11491.3 EKX73325.1 - 0.1 12.4 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) Sugar-bind PF04198.8 EKX73325.1 - 0.11 11.3 0.1 0.17 10.7 0.1 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain Synaptobrevin PF00957.16 EKX73326.1 - 5.3e-08 32.3 5.3 9.2e-08 31.5 0.8 2.1 1 1 1 2 2 2 1 Synaptobrevin DUF869 PF05911.6 EKX73326.1 - 0.001 17.4 1.9 0.0012 17.1 1.3 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) BLOC1_2 PF10046.4 EKX73326.1 - 0.0027 17.8 5.4 0.29 11.3 1.0 2.2 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4201 PF13870.1 EKX73326.1 - 0.0051 16.2 4.2 0.0065 15.9 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Tmemb_cc2 PF10267.4 EKX73326.1 - 0.0092 14.6 1.0 0.012 14.2 0.7 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein KLRAQ PF10205.4 EKX73326.1 - 0.017 15.1 2.6 0.018 15.0 0.1 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF745 PF05335.8 EKX73326.1 - 0.048 13.1 2.5 0.67 9.4 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Med11 PF10280.4 EKX73326.1 - 0.049 13.6 0.5 0.24 11.4 0.1 1.9 2 0 0 2 2 2 0 Mediator complex protein Laminin_II PF06009.7 EKX73326.1 - 0.05 13.3 6.9 0.72 9.6 4.8 2.0 1 1 0 1 1 1 0 Laminin Domain II EAP30 PF04157.11 EKX73326.1 - 0.053 12.6 4.0 0.87 8.7 0.4 2.1 1 1 1 2 2 2 0 EAP30/Vps36 family MCPsignal PF00015.16 EKX73326.1 - 0.066 12.7 1.6 0.47 9.9 0.7 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BCAS2 PF05700.6 EKX73326.1 - 0.07 12.5 2.1 0.093 12.1 1.5 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Baculo_FP PF03258.9 EKX73326.1 - 0.076 12.1 2.2 0.12 11.4 1.5 1.4 1 1 0 1 1 1 0 Baculovirus FP protein DUF2317 PF10079.4 EKX73326.1 - 0.09 11.3 2.2 0.11 11.1 0.7 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) Fzo_mitofusin PF04799.8 EKX73326.1 - 0.092 12.1 2.8 0.38 10.1 0.1 2.1 2 0 0 2 2 2 0 fzo-like conserved region DUF4337 PF14235.1 EKX73326.1 - 0.1 12.4 3.0 0.73 9.6 2.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) CorA PF01544.13 EKX73326.1 - 0.1 11.5 3.3 0.24 10.3 2.3 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Sec20 PF03908.8 EKX73326.1 - 0.11 12.1 1.3 0.79 9.4 0.1 2.2 1 1 0 2 2 2 0 Sec20 Filament PF00038.16 EKX73326.1 - 0.12 11.8 8.2 0.078 12.4 1.4 2.0 1 1 1 2 2 2 0 Intermediate filament protein WXG100 PF06013.7 EKX73326.1 - 0.12 12.3 1.5 1.8 8.6 0.3 2.6 1 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF1664 PF07889.7 EKX73326.1 - 0.12 12.1 5.6 0.45 10.3 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Dor1 PF04124.7 EKX73326.1 - 0.13 10.6 3.7 0.6 8.5 0.1 2.0 1 1 0 2 2 2 0 Dor1-like family Spc7 PF08317.6 EKX73326.1 - 0.16 10.6 4.1 0.21 10.2 2.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1319 PF07028.6 EKX73326.1 - 0.16 12.1 2.5 0.23 11.6 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) ISG65-75 PF11727.3 EKX73326.1 - 0.17 10.9 2.1 0.21 10.6 1.4 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein HisKA PF00512.20 EKX73326.1 - 0.3 11.1 2.2 6.5 6.8 0.1 2.3 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF1409 PF07197.7 EKX73326.1 - 0.32 11.0 4.3 0.51 10.4 0.3 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF1409) OmpH PF03938.9 EKX73326.1 - 0.51 10.2 4.0 1.1 9.1 2.8 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-H PF05837.7 EKX73326.1 - 0.54 10.4 4.2 2.8 8.1 0.8 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4200 PF13863.1 EKX73326.1 - 0.63 9.9 7.5 2.3 8.1 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Syntaxin PF00804.20 EKX73326.1 - 0.99 9.6 7.6 1.2 9.3 1.6 2.1 1 1 0 2 2 2 0 Syntaxin NPV_P10 PF05531.7 EKX73326.1 - 1.8 8.9 4.2 99 3.2 2.9 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein zf-CpG_bind_C PF12269.3 EKX73326.1 - 2 7.8 5.4 6.7 6.1 0.3 2.2 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain H-kinase_dim PF02895.9 EKX73326.1 - 4.3 7.7 6.7 26 5.2 0.4 2.8 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain CTP_transf_2 PF01467.21 EKX73327.1 - 5.7e-21 75.2 0.0 6.8e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Phage_Gp19 PF09355.5 EKX73328.1 - 0.069 13.0 0.0 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 CS PF04969.11 EKX73329.1 - 2.4e-12 47.2 0.7 3.8e-12 46.5 0.5 1.3 1 0 0 1 1 1 1 CS domain SGS PF05002.10 EKX73329.1 - 1.4e-11 43.9 0.7 2.9e-11 42.9 0.5 1.5 1 0 0 1 1 1 1 SGS domain Siah-Interact_N PF09032.6 EKX73329.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Siah interacting protein, N terminal DUF2042 PF09743.4 EKX73330.1 - 3.7e-47 160.9 0.9 8e-47 159.8 0.3 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2042) FAINT PF04385.10 EKX73332.1 - 3.2e-06 26.8 0.1 0.038 13.8 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73333.1 - 0.043 13.6 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, DUF529 VSP PF03302.8 EKX73334.1 - 0.014 14.0 0.1 0.029 13.0 0.1 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein FAINT PF04385.10 EKX73335.1 - 0.00029 20.6 0.2 0.0004 20.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 DUF948 PF06103.6 EKX73336.1 - 0.00053 19.8 1.6 1.4 8.8 0.0 3.5 2 2 1 3 3 3 2 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.1 EKX73336.1 - 0.003 17.5 6.0 0.54 10.3 0.1 3.0 2 2 0 2 2 2 2 Syntaxin-like protein LXG PF04740.7 EKX73336.1 - 0.048 13.4 5.3 2.7 7.7 0.4 2.4 2 0 0 2 2 2 0 LXG domain of WXG superfamily RHSP PF07999.6 EKX73336.1 - 0.47 8.9 3.6 0.26 9.8 0.7 1.7 2 0 0 2 2 2 0 Retrotransposon hot spot protein DUF4298 PF14131.1 EKX73336.1 - 0.51 10.2 2.7 18 5.2 0.3 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4298) Ferritin PF00210.19 EKX73336.1 - 0.62 9.8 3.5 0.44 10.3 0.1 2.3 2 1 0 2 2 2 0 Ferritin-like domain DUF643 PF04867.7 EKX73336.1 - 3.3 8.1 9.4 2.5 8.5 3.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF643) V-SNARE PF05008.10 EKX73336.1 - 5.4 7.2 8.0 0.85 9.8 0.2 3.3 4 0 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus DUF3395 PF11875.3 EKX73339.1 - 4.8e-27 94.4 0.0 9.3e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EKX73339.1 - 3e-15 55.6 0.0 7.2e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain HAT PF02184.11 EKX73339.1 - 0.048 13.4 1.1 3.7 7.3 0.1 2.4 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat Bromo_TP PF07524.8 EKX73340.1 - 0.00045 19.8 0.0 0.00077 19.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated FAINT PF04385.10 EKX73341.1 - 1.4e-05 24.8 2.1 0.0017 18.1 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function, DUF529 RE_ScaI PF09569.5 EKX73341.1 - 0.014 14.8 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 ScaI restriction endonuclease Ribosomal_L6e PF01159.14 EKX73341.1 - 0.058 13.6 1.3 0.091 13.0 0.9 1.3 1 0 0 1 1 1 0 Ribosomal protein L6e FAINT PF04385.10 EKX73342.1 - 6.5e-15 54.7 5.1 1.8e-07 30.9 0.6 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX73342.1 - 1e-06 28.4 4.0 1.6e-06 27.8 2.8 1.1 1 0 0 1 1 1 1 Merozoite Antigen DUF824 PF05688.6 EKX73342.1 - 0.069 12.7 0.0 1.5 8.4 0.0 3.0 4 0 0 4 4 4 0 Salmonella repeat of unknown function (DUF824) FAINT PF04385.10 EKX73344.1 - 2.4e-19 68.9 6.1 5.5e-10 38.9 1.9 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX73344.1 - 0.0003 20.3 1.2 0.00091 18.7 0.1 1.9 2 0 0 2 2 2 1 Merozoite Antigen zf-DHHC PF01529.15 EKX73345.1 - 7.3e-35 119.9 8.0 7.3e-35 119.9 5.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pox_A14 PF05767.7 EKX73345.1 - 0.16 11.9 8.8 0.96 9.4 1.0 2.6 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 CbtA PF09490.5 EKX73345.1 - 0.19 10.9 2.8 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) MRAP PF15183.1 EKX73345.1 - 3.8 7.1 7.4 0.82 9.3 2.1 2.2 2 1 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF2207 PF09972.4 EKX73345.1 - 6.3 5.2 7.3 1 7.8 0.8 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Inhibitor_I42 PF09394.5 EKX73346.1 - 0.072 13.4 2.4 2 8.7 0.0 3.6 3 1 0 3 3 3 0 Chagasin family peptidase inhibitor I42 SPC25 PF06703.6 EKX73346.1 - 0.094 12.2 1.2 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) ubiquitin PF00240.18 EKX73347.1 - 0.004 16.5 0.0 0.0042 16.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Med31 PF05669.7 EKX73348.1 - 2.8e-35 120.1 4.3 4.2e-35 119.5 3.0 1.2 1 0 0 1 1 1 1 SOH1 LANC_like PF05147.8 EKX73351.1 - 0.065 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein EMG1 PF03587.9 EKX73352.1 - 4.1e-13 49.0 0.1 5.3e-13 48.7 0.1 1.5 1 1 0 1 1 1 1 EMG1/NEP1 methyltransferase Myc_N PF01056.13 EKX73352.1 - 0.003 16.7 3.9 0.0034 16.5 2.7 1.1 1 0 0 1 1 1 1 Myc amino-terminal region CDC45 PF02724.9 EKX73352.1 - 0.034 12.1 3.5 0.035 12.1 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EKX73352.1 - 0.037 13.5 4.8 0.053 13.0 3.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin YL1 PF05764.8 EKX73352.1 - 0.061 12.9 10.2 0.11 12.1 7.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nucleo_P87 PF07267.6 EKX73352.1 - 0.072 11.7 3.6 0.084 11.5 2.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Prothymosin PF03247.9 EKX73352.1 - 0.23 11.6 14.8 0.43 10.7 10.3 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family TLP-20 PF06088.6 EKX73352.1 - 0.28 10.8 6.5 0.39 10.3 4.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.1 EKX73352.1 - 0.48 10.0 7.7 0.49 10.0 4.6 1.5 1 1 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 EKX73352.1 - 1.1 9.6 8.9 1.9 8.8 6.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1676 PF07898.8 EKX73352.1 - 8.9 6.6 7.6 34 4.8 3.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1676) rRNA_processing PF08524.6 EKX73354.1 - 7.3e-07 29.0 19.8 7.3e-07 29.0 13.7 2.1 2 0 0 2 2 2 1 rRNA processing DOR PF14839.1 EKX73354.1 - 2.8 7.6 12.6 3.5 7.3 8.2 1.6 1 1 0 1 1 1 0 DOR family CAF-1_p150 PF11600.3 EKX73354.1 - 3.1 7.0 31.9 0.072 12.4 17.1 1.8 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 EKX73354.1 - 4.3 6.5 15.6 5.4 6.2 10.8 1.1 1 0 0 1 1 1 0 SprA-related family Plasmid_parti PF01672.11 EKX73355.1 - 0.097 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative plasmid partition protein Zn_Tnp_IS1595 PF12760.2 EKX73355.1 - 3.6 7.4 8.7 2.4 8.0 0.5 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Fcf1 PF04900.7 EKX73356.1 - 5.7e-23 80.9 0.1 1.8e-21 76.1 0.0 2.1 2 0 0 2 2 2 1 Fcf1 MNE1 PF13762.1 EKX73356.1 - 0.00029 20.9 0.0 0.00046 20.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial splicing apparatus component WD40 PF00400.27 EKX73359.1 - 7.9e-15 54.0 7.2 1.9e-05 24.3 0.0 5.0 4 1 0 4 4 4 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKX73359.1 - 0.012 15.3 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region BCDHK_Adom3 PF10436.4 EKX73360.1 - 0.0086 15.6 0.4 0.018 14.5 0.3 1.7 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Rrn6 PF10214.4 EKX73360.1 - 0.016 13.3 1.5 0.019 13.1 1.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor NPV_P10 PF05531.7 EKX73360.1 - 0.071 13.3 0.5 0.22 11.7 0.3 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 EKX73360.1 - 0.076 11.4 12.0 0.089 11.2 8.3 1.1 1 0 0 1 1 1 0 AAA domain Ycf1 PF05758.7 EKX73360.1 - 0.56 7.8 10.4 0.68 7.5 7.2 1.1 1 0 0 1 1 1 0 Ycf1 DUF848 PF05852.6 EKX73360.1 - 0.68 9.7 11.3 2.7 7.8 0.7 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4463 PF14703.1 EKX73360.1 - 1.3 9.6 11.9 0.96 10.0 6.9 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4463) DUF2570 PF10828.3 EKX73360.1 - 5 6.7 9.0 0.17 11.5 1.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2570) DUF883 PF05957.8 EKX73360.1 - 8.8 6.7 7.0 3.9 7.9 1.6 2.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) ABC_tran PF00005.22 EKX73361.1 - 4.1e-32 111.3 0.0 5e-17 62.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EKX73361.1 - 1.6e-06 28.2 12.2 0.0046 16.9 0.2 4.9 6 0 0 6 6 5 2 AAA domain AAA_16 PF13191.1 EKX73361.1 - 3.2e-06 27.2 0.1 0.0025 17.8 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain ArgK PF03308.11 EKX73361.1 - 5e-06 25.4 0.5 5.8e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 ArgK protein AAA_29 PF13555.1 EKX73361.1 - 9.4e-06 25.0 1.4 0.14 11.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.1 EKX73361.1 - 0.00014 21.4 0.1 0.018 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EKX73361.1 - 0.00015 22.1 4.4 0.039 14.2 0.7 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EKX73361.1 - 0.0002 20.5 0.5 0.13 11.3 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EKX73361.1 - 0.00023 20.6 0.0 0.06 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_membrane PF00664.18 EKX73361.1 - 0.00025 20.5 19.5 0.00025 20.5 13.5 3.2 4 0 0 4 4 3 1 ABC transporter transmembrane region AAA_17 PF13207.1 EKX73361.1 - 0.00034 21.4 0.0 0.18 12.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKX73361.1 - 0.00067 19.9 0.3 0.36 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EKX73361.1 - 0.0014 18.4 0.7 0.24 11.2 0.0 2.5 2 0 0 2 2 2 1 Dynamin family MobB PF03205.9 EKX73361.1 - 0.0015 18.2 0.3 0.24 11.0 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EKX73361.1 - 0.0021 17.1 0.4 1.7 7.6 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.18 EKX73361.1 - 0.0037 17.2 0.8 0.43 10.5 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EKX73361.1 - 0.0043 16.5 0.3 0.71 9.3 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 EKX73361.1 - 0.0046 16.8 4.1 0.043 13.6 0.2 2.7 3 0 0 3 3 3 1 Domain of unknown function DUF87 T2SE PF00437.15 EKX73361.1 - 0.0052 15.7 0.4 0.86 8.4 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_15 PF13175.1 EKX73361.1 - 0.007 15.4 1.0 0.88 8.5 0.0 3.3 4 0 0 4 4 4 1 AAA ATPase domain Miro PF08477.8 EKX73361.1 - 0.0097 16.3 0.2 4.7 7.7 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein SMC_N PF02463.14 EKX73361.1 - 0.012 14.8 2.2 0.063 12.5 0.2 2.4 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EKX73361.1 - 0.017 15.2 0.1 4.7 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EKX73361.1 - 0.059 11.9 0.6 5.4 5.5 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 EKX73361.1 - 0.06 13.1 1.4 5 6.9 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EKX73361.1 - 0.06 13.2 0.1 5.2 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EKX73361.1 - 0.061 12.3 0.1 7.5 5.4 0.0 2.7 3 0 0 3 3 3 0 KAP family P-loop domain NACHT PF05729.7 EKX73361.1 - 0.064 12.9 0.7 12 5.4 0.1 2.6 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.8 EKX73361.1 - 0.075 11.9 0.8 1.3 7.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 EKX73361.1 - 0.076 12.4 0.3 10 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain NB-ARC PF00931.17 EKX73361.1 - 0.11 11.2 0.1 0.75 8.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain FAINT PF04385.10 EKX73362.1 - 7.9e-73 240.3 83.2 4.3e-05 23.2 1.4 21.3 21 0 0 21 21 21 19 Domain of unknown function, DUF529 TruB-C_2 PF09157.6 EKX73362.1 - 0.18 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal MHCassoc_trimer PF08831.5 EKX73363.1 - 0.0034 17.2 0.0 0.0084 15.9 0.0 1.6 1 0 0 1 1 1 1 Class II MHC-associated invariant chain trimerisation domain MatE PF01554.13 EKX73364.1 - 2.6e-05 23.9 0.6 0.012 15.2 0.0 2.2 2 0 0 2 2 2 2 MatE DUF4149 PF13664.1 EKX73364.1 - 4 7.5 11.7 3e+02 1.5 8.1 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) RFC1 PF08519.7 EKX73365.1 - 5.3e-38 130.2 0.1 1.4e-37 128.8 0.1 1.7 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.24 EKX73365.1 - 1.1e-11 45.0 0.0 2.7e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 EKX73365.1 - 7.4e-08 32.4 0.1 2.3e-07 30.8 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA_22 PF13401.1 EKX73365.1 - 0.00027 21.1 0.0 0.0054 16.8 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKX73365.1 - 0.00036 21.3 0.0 0.0018 19.0 0.0 2.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EKX73365.1 - 0.0016 17.5 0.0 0.0053 15.8 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EKX73365.1 - 0.0039 17.1 0.0 0.0092 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EKX73365.1 - 0.0041 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EKX73365.1 - 0.0043 16.1 0.0 0.025 13.6 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EKX73365.1 - 0.018 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activ_2 PF14532.1 EKX73365.1 - 0.028 14.4 0.0 0.12 12.3 0.0 2.1 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 EKX73365.1 - 0.038 13.9 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain DNA_pol3_delta PF06144.8 EKX73365.1 - 0.039 13.4 1.4 0.049 13.1 0.0 2.0 2 0 0 2 2 1 0 DNA polymerase III, delta subunit AAA_28 PF13521.1 EKX73365.1 - 0.05 13.5 0.1 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EKX73365.1 - 0.057 13.1 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Abhydrolase_1 PF00561.15 EKX73365.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAINT PF04385.10 EKX73367.1 - 8.6e-08 31.9 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73370.1 - 4.2e-10 39.3 2.5 0.00043 20.0 0.4 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF605 PF04652.11 EKX73372.1 - 0.69 9.2 14.8 1.2 8.4 10.3 1.3 1 0 0 1 1 1 0 Vta1 like Abhydrolase_6 PF12697.2 EKX73373.1 - 4.3e-15 56.2 0.0 7.1e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX73373.1 - 1e-10 41.5 0.0 2.7e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX73373.1 - 1.3e-08 34.6 0.4 3.5e-08 33.1 0.2 1.8 1 0 0 1 1 1 1 Putative lysophospholipase FAINT PF04385.10 EKX73373.1 - 1.4e-05 24.8 8.9 0.0081 15.9 1.1 4.3 3 0 0 3 3 3 2 Domain of unknown function, DUF529 Abhydrolase_1 PF00561.15 EKX73373.1 - 9.8e-05 22.0 1.8 0.0066 16.0 0.1 3.0 2 1 1 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKX73373.1 - 0.0034 16.6 0.4 2.6 7.2 0.0 3.1 3 1 1 4 4 4 2 Prolyl oligopeptidase family PGAP1 PF07819.8 EKX73373.1 - 0.0055 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.7 EKX73373.1 - 0.01 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.9 EKX73373.1 - 0.034 13.4 0.0 0.45 9.7 0.0 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF2305 PF10230.4 EKX73373.1 - 0.057 12.8 0.6 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 EKX73373.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAINT PF04385.10 EKX73374.1 - 0.0031 17.3 1.2 0.0059 16.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function, DUF529 Collagen PF01391.13 EKX73375.1 - 0.057 12.9 13.8 0.18 11.3 9.6 1.8 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Ribosomal_S30 PF04758.9 EKX73377.1 - 2.2e-26 91.3 10.1 2.5e-26 91.1 7.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Sec1 PF00995.18 EKX73378.1 - 2.9e-111 372.8 3.9 3.4e-111 372.6 2.7 1.0 1 0 0 1 1 1 1 Sec1 family DIRP PF06584.8 EKX73379.1 - 0.078 12.8 2.3 0.71 9.7 0.3 2.2 2 0 0 2 2 2 0 DIRP FAINT PF04385.10 EKX73381.1 - 6.7e-13 48.3 3.6 1.8e-05 24.5 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function, DUF529 DUF1664 PF07889.7 EKX73382.1 - 0.28 10.9 13.4 4.3 7.1 2.0 4.4 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) Hpt PF01627.18 EKX73382.1 - 0.38 10.7 2.9 0.56 10.2 0.0 2.7 3 1 0 3 3 3 0 Hpt domain TMPIT PF07851.8 EKX73382.1 - 0.41 9.6 5.2 0.45 9.5 0.0 2.2 2 0 0 2 2 2 0 TMPIT-like protein IncA PF04156.9 EKX73382.1 - 1.4 8.4 12.4 5.6 6.5 1.0 2.6 2 1 0 2 2 2 0 IncA protein FAINT PF04385.10 EKX73383.1 - 0.00016 21.4 0.0 0.0003 20.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73384.1 - 2.3e-30 104.2 8.5 3.8e-07 29.8 0.0 6.1 5 0 0 5 5 5 5 Domain of unknown function, DUF529 Pox_L3_FP4 PF03339.9 EKX73387.1 - 0.022 13.2 0.6 0.039 12.4 0.0 1.6 2 0 0 2 2 2 0 Poxvirus L3/FP4 protein EMA PF02488.10 EKX73388.1 - 0.016 14.7 0.4 0.021 14.3 0.3 1.1 1 0 0 1 1 1 0 Merozoite Antigen FAINT PF04385.10 EKX73388.1 - 0.14 12.0 1.8 0.25 11.1 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function, DUF529 ATP-synt_ab PF00006.20 EKX73389.1 - 1.6e-70 236.9 0.0 2.4e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EKX73389.1 - 1.9e-22 79.8 0.7 5.4e-22 78.4 0.1 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EKX73389.1 - 2.5e-16 59.6 2.2 8.1e-16 58.0 1.5 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EKX73389.1 - 2.3e-07 30.6 1.6 4.5e-07 29.6 1.1 1.5 1 0 0 1 1 1 1 HAS barrel domain AAA_25 PF13481.1 EKX73389.1 - 0.012 14.9 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Tex_N PF09371.5 EKX73389.1 - 0.047 12.9 0.1 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Cpn10 PF00166.16 EKX73389.1 - 0.058 13.3 0.1 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit CSD PF00313.17 EKX73390.1 - 1.2e-23 82.6 0.1 1.6e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 EKX73390.1 - 0.00081 18.8 0.2 0.0021 17.5 0.1 1.7 1 1 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.18 EKX73390.1 - 0.0014 18.6 0.1 0.0019 18.2 0.1 1.1 1 0 0 1 1 1 1 S1 RNA binding domain Sin3_corepress PF08295.7 EKX73390.1 - 0.059 13.1 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Sin3 family co-repressor CECR6_TMEM121 PF14997.1 EKX73391.1 - 4.3e-15 55.8 8.2 4.3e-15 55.8 5.7 3.0 3 1 0 3 3 3 1 CECR6/TMEM121 family S_100 PF01023.14 EKX73391.1 - 0.18 11.1 1.3 3.7 6.9 0.1 3.2 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain ABC_tran PF00005.22 EKX73392.1 - 2.2e-30 105.7 0.0 7.4e-17 61.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 EKX73392.1 - 7.1e-07 29.3 0.2 0.0013 18.7 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EKX73392.1 - 8.2e-06 25.9 4.3 0.02 14.8 0.1 4.2 5 0 0 5 5 4 2 AAA domain AAA_23 PF13476.1 EKX73392.1 - 8.9e-06 26.1 1.5 0.036 14.3 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EKX73392.1 - 1.5e-05 24.6 0.3 0.0026 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKX73392.1 - 5.7e-05 23.4 0.2 0.35 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EKX73392.1 - 8.4e-05 22.0 1.0 0.16 11.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EKX73392.1 - 0.00013 21.4 0.1 0.058 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EKX73392.1 - 0.00026 19.8 1.4 0.00032 19.5 0.1 1.6 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 EKX73392.1 - 0.00038 21.2 0.0 0.46 11.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EKX73392.1 - 0.0011 18.1 0.3 0.66 9.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin T2SE PF00437.15 EKX73392.1 - 0.0012 17.8 1.1 1.3 7.8 0.0 2.9 3 0 0 3 3 3 2 Type II/IV secretion system protein DUF258 PF03193.11 EKX73392.1 - 0.0014 17.8 1.3 0.073 12.2 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EKX73392.1 - 0.0021 17.7 0.2 0.27 10.9 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EKX73392.1 - 0.0021 17.5 0.7 0.78 9.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 EKX73392.1 - 0.0027 17.5 2.9 0.042 13.6 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 SMC_N PF02463.14 EKX73392.1 - 0.0041 16.3 0.4 0.16 11.2 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 EKX73392.1 - 0.0066 16.0 1.0 0.18 11.3 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_NifH PF00142.13 EKX73392.1 - 0.0076 15.4 0.3 0.68 9.0 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF2791 PF10923.3 EKX73392.1 - 0.01 14.4 0.0 0.1 11.2 0.0 2.1 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) AAA_19 PF13245.1 EKX73392.1 - 0.011 15.4 1.1 4.2 7.1 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain SRP54 PF00448.17 EKX73392.1 - 0.03 13.7 0.7 0.44 9.9 0.0 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EKX73392.1 - 0.035 14.2 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EKX73392.1 - 0.04 14.4 0.1 18 5.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 EKX73392.1 - 0.052 13.2 1.3 2.2 7.8 0.1 2.4 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 EKX73392.1 - 0.055 12.3 1.0 0.37 9.6 0.1 2.5 3 0 0 3 3 3 0 NB-ARC domain MMR_HSR1 PF01926.18 EKX73392.1 - 0.06 13.3 0.1 0.62 10.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 EKX73392.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EKX73392.1 - 0.066 13.0 0.1 7.7 6.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EKX73392.1 - 0.085 12.6 0.3 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family TrwB_AAD_bind PF10412.4 EKX73392.1 - 0.11 11.1 0.6 9.5 4.7 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 EKX73392.1 - 0.12 11.8 1.3 13 5.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.10 EKX73392.1 - 0.12 11.1 0.0 10 4.9 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain NTPase_1 PF03266.10 EKX73392.1 - 0.17 11.5 1.1 5.7 6.6 0.1 2.4 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.21 EKX73392.1 - 0.18 11.2 0.2 5.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Arteri_nucleo PF01481.11 EKX73394.1 - 0.13 12.3 0.1 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein SMK-1 PF04802.10 EKX73395.1 - 1.7e-22 79.9 5.6 1.7e-22 79.9 3.8 2.1 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 TFIIA_gamma_N PF02268.11 EKX73395.1 - 0.029 13.9 1.5 2.7 7.6 0.3 2.6 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain Glyco_hydro_20b PF02838.10 EKX73395.1 - 0.052 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 DNA_pol_E_B PF04042.11 EKX73396.1 - 1.2e-26 93.2 0.4 1.9e-26 92.5 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Orbi_VP5 PF00901.12 EKX73396.1 - 0.016 13.4 0.1 0.024 12.8 0.1 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 BING4CT PF08149.6 EKX73397.1 - 1.3e-32 111.1 0.0 5.5e-31 105.9 0.0 2.7 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 EKX73397.1 - 0.00011 21.9 0.3 0.0074 16.1 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Syntaxin PF00804.20 EKX73397.1 - 0.072 13.2 5.5 0.051 13.7 2.0 2.0 2 0 0 2 2 2 0 Syntaxin Cwf_Cwc_15 PF04889.7 EKX73398.1 - 2.3e-45 155.2 22.7 3.1e-43 148.2 15.7 2.4 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3295 PF11702.3 EKX73398.1 - 0.1 11.5 8.3 0.14 11.1 5.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3295) DUF2890 PF11081.3 EKX73398.1 - 0.17 11.9 10.8 0.021 14.9 4.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Cytochrom_C552 PF02335.10 EKX73398.1 - 1.1 7.9 4.4 0.57 8.8 1.7 1.4 1 1 0 1 1 1 0 Cytochrome c552 DUF1697 PF08002.6 EKX73398.1 - 1.4 8.9 4.6 1.4 8.9 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1697) YchF-GTPase_C PF06071.8 EKX73399.1 - 2.7e-39 132.8 0.1 7e-39 131.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EKX73399.1 - 6.4e-17 61.5 0.0 1.8e-16 60.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKX73399.1 - 1.1e-05 24.7 0.0 2.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.24 EKX73399.1 - 0.0037 17.4 0.1 0.014 15.5 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKX73399.1 - 0.0057 17.4 0.1 0.12 13.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 EKX73399.1 - 0.019 14.7 0.2 2 8.2 0.0 3.0 2 1 1 3 3 3 0 Dynamin family ABC_tran PF00005.22 EKX73399.1 - 0.1 12.8 0.0 1.9 8.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter NuA4 PF09340.5 EKX73400.1 - 0.00062 19.3 0.3 0.0024 17.4 0.1 2.2 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Cmc1 PF08583.5 EKX73401.1 - 5.8e-12 45.2 6.1 6.5e-12 45.0 4.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 EKX73401.1 - 0.072 12.5 1.4 0.099 12.0 1.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.8 EKX73401.1 - 0.078 12.9 2.6 0.3 11.0 1.7 1.9 1 1 0 1 1 1 0 CHCH domain IL4Ra_N PF09238.5 EKX73401.1 - 0.089 12.9 0.3 0.1 12.7 0.2 1.2 1 0 0 1 1 1 0 Interleukin-4 receptor alpha chain, N-terminal TRAP-gamma PF07074.7 EKX73401.1 - 0.15 11.5 0.3 0.17 11.4 0.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3316 PF11777.3 EKX73402.1 - 0.021 14.6 0.7 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) Pex14_N PF04695.8 EKX73402.1 - 0.045 13.7 0.7 0.11 12.5 0.5 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-MYND PF01753.13 EKX73404.1 - 1.9e-05 24.3 7.6 1.9e-05 24.3 5.3 1.9 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 EKX73404.1 - 0.00011 21.9 3.8 0.00027 20.7 2.7 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Piwi PF02171.12 EKX73404.1 - 0.017 14.1 0.0 0.037 13.0 0.0 1.5 1 0 0 1 1 1 0 Piwi domain zf-HIT PF04438.11 EKX73404.1 - 0.2 11.3 6.5 0.54 9.9 4.5 1.8 1 0 0 1 1 1 0 HIT zinc finger MRP-S25 PF13741.1 EKX73405.1 - 5.5e-05 22.7 0.4 0.0019 17.7 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 EKX73405.1 - 0.078 12.8 1.6 0.081 12.8 0.1 1.8 2 1 0 2 2 2 0 Mitochondrial ribosomal protein S23 TGT PF01702.13 EKX73406.1 - 8.3e-30 103.8 0.0 1.1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase TPR_11 PF13414.1 EKX73407.1 - 4.4e-72 237.6 39.4 1.9e-21 75.4 0.5 6.8 6 1 0 7 7 7 6 TPR repeat TPR_1 PF00515.23 EKX73407.1 - 4.3e-58 190.6 41.4 4.4e-08 32.3 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 EKX73407.1 - 1.2e-47 155.9 34.6 1.4e-05 24.6 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 EKX73407.1 - 1e-26 92.6 20.4 4.3e-09 36.1 0.4 7.3 3 2 4 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 EKX73407.1 - 3.3e-23 79.9 21.0 0.0014 18.6 0.1 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EKX73407.1 - 5.3e-23 79.0 40.2 0.00029 20.3 0.1 9.9 9 1 1 10 10 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EKX73407.1 - 7e-23 80.7 12.0 6.1e-05 23.5 0.0 7.1 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EKX73407.1 - 1.4e-21 76.5 25.1 6.6e-07 29.5 0.3 7.3 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EKX73407.1 - 3.1e-19 67.7 9.2 0.75 10.5 0.0 9.4 5 3 5 10 10 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 EKX73407.1 - 3.8e-16 58.7 1.6 0.019 14.8 0.0 6.5 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 EKX73407.1 - 7.6e-15 53.4 19.6 0.0051 16.5 0.3 9.1 9 0 0 9 9 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EKX73407.1 - 9e-10 38.5 24.6 4.8e-06 26.6 3.6 5.2 5 1 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EKX73407.1 - 5.6e-06 26.3 9.1 0.53 10.4 0.0 5.7 4 1 2 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKX73407.1 - 9.3e-05 22.2 18.9 4.3 7.2 0.0 8.2 8 0 0 8 8 8 1 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.2 EKX73407.1 - 0.00026 20.8 6.5 3.8 7.3 0.0 4.9 4 2 0 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 EKX73407.1 - 0.00028 21.1 28.8 5 7.7 0.5 8.4 8 1 1 9 9 7 1 Tetratricopeptide repeat Coatomer_E PF04733.9 EKX73407.1 - 0.00037 19.7 11.2 0.041 13.0 0.4 4.5 3 1 1 5 5 5 2 Coatomer epsilon subunit TPR_10 PF13374.1 EKX73407.1 - 0.0011 18.7 8.2 5.3 7.1 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.7 EKX73407.1 - 0.0059 16.3 12.8 0.012 15.3 0.6 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 EKX73407.1 - 0.026 14.3 14.4 19 5.2 0.0 6.2 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.1 EKX73407.1 - 0.065 13.4 5.1 4.7 7.4 0.2 3.4 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation SNN_linker PF09050.5 EKX73407.1 - 0.12 11.9 0.9 0.29 10.7 0.6 1.7 1 0 0 1 1 1 0 Stannin unstructured linker DnaI_N PF07319.6 EKX73407.1 - 0.79 10.0 6.9 0.38 11.0 0.1 3.4 3 1 0 3 3 3 0 Primosomal protein DnaI N-terminus PPR PF01535.15 EKX73407.1 - 0.89 9.6 13.8 8.5 6.6 0.1 6.1 6 0 0 6 6 5 0 PPR repeat SHNi-TPR PF10516.4 EKX73407.1 - 1.4 8.1 9.8 20 4.5 0.0 5.6 8 0 0 8 8 6 0 SHNi-TPR Sel1 PF08238.7 EKX73407.1 - 5.2 7.8 9.2 3.5 8.3 0.2 4.0 4 0 0 4 4 3 0 Sel1 repeat Clathrin PF00637.15 EKX73407.1 - 8.4 5.9 20.0 0.18 11.4 3.9 3.1 4 0 0 4 4 4 0 Region in Clathrin and VPS AAA_5 PF07728.9 EKX73409.1 - 1.7e-89 296.7 0.0 4.9e-20 71.6 0.0 8.8 8 0 0 8 8 8 7 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EKX73409.1 - 4.2e-28 97.5 0.0 5.1e-10 39.0 0.0 6.1 7 0 0 7 7 5 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EKX73409.1 - 1.6e-19 70.4 0.0 8.9e-05 22.7 0.0 5.8 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKX73409.1 - 4.3e-15 56.6 0.0 0.052 14.3 0.0 7.6 6 0 0 6 6 6 3 AAA domain AAA_18 PF13238.1 EKX73409.1 - 1.3e-14 54.5 1.5 0.08 13.2 0.2 7.0 6 1 0 6 6 5 4 AAA domain AAA_16 PF13191.1 EKX73409.1 - 4.2e-14 52.9 0.4 0.041 13.8 0.0 5.8 5 0 0 5 5 5 3 AAA ATPase domain Sigma54_activ_2 PF14532.1 EKX73409.1 - 1.8e-12 47.4 0.0 0.055 13.5 0.0 6.1 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_22 PF13401.1 EKX73409.1 - 1.8e-12 47.5 0.0 0.45 10.6 0.0 6.2 5 0 0 5 5 5 3 AAA domain Sigma54_activat PF00158.21 EKX73409.1 - 1.8e-10 40.5 0.0 0.016 14.7 0.0 5.1 5 1 0 5 5 4 2 Sigma-54 interaction domain UPF0079 PF02367.12 EKX73409.1 - 1.5e-09 37.5 1.4 0.18 11.4 0.0 4.8 4 0 0 4 4 4 2 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EKX73409.1 - 8e-09 34.7 1.3 1.8 7.3 0.0 5.3 5 0 0 5 5 5 2 Type II/IV secretion system protein AAA_33 PF13671.1 EKX73409.1 - 9.9e-09 35.2 0.0 1.3 8.8 0.0 5.8 5 1 0 5 5 5 2 AAA domain AAA_19 PF13245.1 EKX73409.1 - 1.4e-08 34.3 4.8 0.0073 16.0 0.0 4.8 5 0 0 5 5 4 2 Part of AAA domain Miro PF08477.8 EKX73409.1 - 2e-07 31.5 0.4 0.19 12.2 0.0 5.8 5 0 0 5 5 5 1 Miro-like protein AAA_29 PF13555.1 EKX73409.1 - 3e-07 29.8 0.4 5.7 6.5 0.0 5.4 5 0 0 5 5 5 0 P-loop containing region of AAA domain NACHT PF05729.7 EKX73409.1 - 5.6e-07 29.3 0.2 1.4 8.5 0.0 4.7 4 0 0 4 4 4 2 NACHT domain Mg_chelatase PF01078.16 EKX73409.1 - 1.3e-06 27.6 1.1 0.17 11.0 0.0 6.2 6 1 1 7 7 7 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EKX73409.1 - 1.4e-06 28.6 0.4 0.085 13.1 0.0 4.9 4 0 0 4 4 4 1 ABC transporter RNA_helicase PF00910.17 EKX73409.1 - 3.3e-06 27.2 0.9 8.8 6.5 0.0 6.0 6 0 0 6 6 4 0 RNA helicase MobB PF03205.9 EKX73409.1 - 1.8e-05 24.4 4.0 2.4 7.8 0.0 5.5 6 0 0 6 6 6 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EKX73409.1 - 2.3e-05 23.5 0.1 3.6 6.6 0.0 5.1 6 0 0 6 6 5 1 Zeta toxin PduV-EutP PF10662.4 EKX73409.1 - 4.8e-05 22.8 0.2 0.79 9.2 0.0 3.8 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.7 EKX73409.1 - 0.00016 20.7 0.2 1 8.3 0.0 3.8 4 0 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EKX73409.1 - 0.0002 20.2 1.1 0.31 9.7 0.1 3.3 3 0 0 3 3 3 2 TIP49 C-terminus ResIII PF04851.10 EKX73409.1 - 0.00021 21.1 0.0 1.5 8.5 0.0 3.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 EKX73409.1 - 0.00051 19.5 0.1 5.7 6.3 0.0 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_25 PF13481.1 EKX73409.1 - 0.0013 18.1 0.0 3.3 7.0 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.1 EKX73409.1 - 0.0024 17.4 0.0 16 5.0 0.0 4.2 4 0 0 4 4 4 0 AAA domain ATP-synt_ab PF00006.20 EKX73409.1 - 0.0037 16.7 0.0 0.55 9.6 0.0 2.9 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain Phe_ZIP PF08916.6 EKX73409.1 - 0.011 16.0 1.0 0.86 9.9 0.0 3.0 2 0 0 2 2 2 0 Phenylalanine zipper SRP54 PF00448.17 EKX73409.1 - 0.039 13.3 1.4 5.8 6.3 0.0 3.7 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 EKX73409.1 - 0.042 13.8 3.7 33 4.4 0.0 5.4 6 0 0 6 6 5 0 AAA domain FtsK_SpoIIIE PF01580.13 EKX73409.1 - 0.23 10.9 4.4 10 5.5 0.1 3.9 5 0 0 5 5 3 0 FtsK/SpoIIIE family DUF3482 PF11981.3 EKX73409.1 - 2.3 7.3 5.4 0.25 10.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) DBI_PRT PF02277.12 EKX73409.1 - 6.1 5.8 0.2 16 4.4 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosyltransferase MAM33 PF02330.11 EKX73410.1 - 7e-19 68.4 1.1 8.3e-17 61.6 0.8 2.1 1 1 0 1 1 1 1 Mitochondrial glycoprotein DUF2095 PF09868.4 EKX73410.1 - 0.063 13.0 0.2 9.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) Peptidase_M24 PF00557.19 EKX73412.1 - 9.6e-46 155.9 0.1 1.2e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Tweety PF04906.8 EKX73412.1 - 0.17 10.3 0.0 0.29 9.5 0.0 1.3 1 0 0 1 1 1 0 Tweety COX15-CtaA PF02628.10 EKX73413.1 - 5.9e-74 248.6 5.9 6.8e-74 248.4 4.1 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein RNase_H2-Ydr279 PF09468.5 EKX73414.1 - 1.1e-28 100.2 0.1 2.8e-28 99.0 0.1 1.5 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF1077 PF06417.7 EKX73415.1 - 1.2e-12 47.2 0.9 1.6e-12 46.8 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF3985 PF13153.1 EKX73415.1 - 0.0011 18.6 1.3 0.0025 17.6 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3985) NPCC PF08058.6 EKX73415.1 - 0.46 10.3 3.6 0.65 9.8 2.5 1.2 1 0 0 1 1 1 0 Nuclear pore complex component Clathrin_lg_ch PF01086.12 EKX73416.1 - 0.00017 21.6 14.7 0.0002 21.3 10.2 1.1 1 0 0 1 1 1 1 Clathrin light chain Phage_min_cap2 PF06152.6 EKX73416.1 - 0.024 13.6 4.8 0.027 13.4 3.3 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 CAF-1_p150 PF11600.3 EKX73416.1 - 0.066 12.5 13.9 0.09 12.1 9.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GLYCAM-1 PF05242.6 EKX73416.1 - 1.3 8.9 7.8 2.7 7.9 5.5 1.6 1 1 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) V-ATPase_H_C PF11698.3 EKX73418.1 - 1.5 8.7 6.9 2.9 7.8 0.1 3.8 3 0 0 3 3 3 0 V-ATPase subunit H FAINT PF04385.10 EKX73419.1 - 9.7e-17 60.5 9.1 3.1e-06 26.9 0.3 4.6 4 0 0 4 4 4 4 Domain of unknown function, DUF529 SHOCT PF09851.4 EKX73419.1 - 6.4 6.4 7.2 0.19 11.2 0.2 2.0 2 0 0 2 2 2 0 Short C-terminal domain Tropomyosin_1 PF12718.2 EKX73421.1 - 0.00028 20.7 19.2 0.00028 20.7 13.3 8.3 2 2 4 6 6 6 1 Tropomyosin like GAS PF13851.1 EKX73421.1 - 0.0039 16.3 23.4 0.0039 16.3 16.2 8.1 2 1 5 8 8 8 4 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EKX73421.1 - 0.0042 16.3 2.5 0.0042 16.3 1.7 5.8 2 1 3 5 5 5 3 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EKX73421.1 - 0.005 16.6 14.6 0.005 16.6 10.1 13.4 7 4 5 12 12 12 4 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EKX73421.1 - 0.0057 16.2 15.8 0.0057 16.2 11.0 8.7 2 2 6 8 8 8 4 IncA protein ADIP PF11559.3 EKX73421.1 - 0.006 16.4 5.0 0.006 16.4 3.5 10.6 2 2 5 10 10 10 4 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 EKX73421.1 - 0.38 8.4 153.5 0.016 12.9 85.7 3.8 2 1 0 2 2 2 0 Myosin tail BOP1NT PF08145.7 EKX73422.1 - 3.4e-97 325.2 9.3 5.2e-97 324.6 6.4 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EKX73422.1 - 0.2 11.5 2.0 1.7 8.6 0.4 3.1 4 0 0 4 4 4 0 WD domain, G-beta repeat RGCC PF15151.1 EKX73422.1 - 0.84 10.0 5.2 0.4 11.1 1.2 2.2 2 0 0 2 2 2 0 Response gene to complement 32 protein family cobW PF02492.14 EKX73425.1 - 3.4e-33 114.5 0.1 7.3e-33 113.4 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EKX73425.1 - 7.2e-07 28.8 0.0 1.6e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain FluMu_gp41 PF10109.4 EKX73425.1 - 0.0039 17.0 0.0 0.092 12.6 0.0 2.3 2 0 0 2 2 2 1 Mu-like prophage FluMu protein gp41 AAA_33 PF13671.1 EKX73425.1 - 0.0051 16.6 0.2 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF1875 PF08961.5 EKX73425.1 - 0.0054 16.0 0.5 0.0089 15.3 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) AAA_18 PF13238.1 EKX73425.1 - 0.015 15.6 0.4 0.11 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EKX73425.1 - 0.019 15.4 0.5 0.46 10.9 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_19 PF13245.1 EKX73425.1 - 0.028 14.1 0.2 0.1 12.3 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 EKX73425.1 - 0.033 12.9 1.1 3.7 6.2 0.1 2.5 2 0 0 2 2 2 0 ArgK protein Rox3 PF08633.5 EKX73425.1 - 0.037 14.3 0.2 0.06 13.6 0.2 1.3 1 0 0 1 1 1 0 Rox3 mediator complex subunit AAA_22 PF13401.1 EKX73425.1 - 0.037 14.1 0.6 0.18 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain FlgN PF05130.7 EKX73425.1 - 0.041 14.1 2.6 0.057 13.6 0.5 2.1 2 0 0 2 2 2 0 FlgN protein AAA PF00004.24 EKX73425.1 - 0.056 13.6 0.8 4.6 7.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EKX73425.1 - 0.073 12.7 1.2 0.19 11.4 0.5 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Porin_3 PF01459.17 EKX73426.1 - 7.1e-08 32.0 0.2 1.4e-07 31.1 0.2 1.4 1 1 0 1 1 1 1 Eukaryotic porin Ribosomal_L35Ae PF01247.13 EKX73427.1 - 1.5e-41 140.0 1.0 1.8e-41 139.8 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EKX73427.1 - 0.0023 17.8 0.0 0.6 10.0 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Cyclin_N PF00134.18 EKX73428.1 - 0.00023 20.7 0.7 0.00023 20.7 0.5 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain FAINT PF04385.10 EKX73429.1 - 2.7e-05 23.9 0.0 6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function, DUF529 DUF3508 PF12018.3 EKX73429.1 - 0.32 9.9 4.3 0.62 9.0 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3508) RVT_1 PF00078.22 EKX73430.1 - 1.8e-17 63.3 0.0 3.5e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAINT PF04385.10 EKX73432.1 - 1.1e-16 60.3 1.8 2.5e-08 33.6 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX73432.1 - 1.7e-05 24.4 0.3 0.087 12.2 0.1 2.2 1 1 1 2 2 2 2 Merozoite Antigen RVT_1 PF00078.22 EKX73433.1 - 1.4e-34 119.3 0.1 2.5e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAINT PF04385.10 EKX73435.1 - 3.9e-08 33.0 0.2 1e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73436.1 - 6.5e-12 45.1 5.5 7.4e-06 25.7 1.2 2.8 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF4398 PF14346.1 EKX73436.1 - 0.058 13.4 4.9 1.6 8.8 3.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) COG2 PF06148.6 EKX73436.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.6 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.7 EKX73436.1 - 3.1 7.5 11.1 1.1 9.0 0.3 3.6 3 1 1 4 4 4 0 Laminin Domain II Tbf5 PF06331.7 EKX73437.1 - 3.8e-11 42.6 0.1 4.7e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 ABC2_membrane_4 PF12730.2 EKX73439.1 - 0.58 9.2 15.7 0.92 8.6 10.9 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-DHHC PF01529.15 EKX73440.1 - 4.4e-30 104.3 10.2 4.4e-30 104.3 7.1 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase IncA PF04156.9 EKX73440.1 - 0.056 13.0 0.2 0.056 13.0 0.1 1.9 2 0 0 2 2 2 0 IncA protein DUF2207 PF09972.4 EKX73440.1 - 0.64 8.5 5.5 0.28 9.7 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.1 EKX73440.1 - 0.84 9.0 0.0 0.84 9.0 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.20 EKX73441.1 - 7.8e-67 225.1 0.0 2.9e-66 223.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.24 EKX73441.1 - 8.3e-63 208.2 2.9 1.3e-18 66.5 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 EKX73441.1 - 1.1e-32 113.1 0.0 3.6e-32 111.4 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 EKX73441.1 - 3.6e-06 26.1 0.0 6.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Cupin_2 PF07883.6 EKX73441.1 - 7.1e-05 22.2 5.1 0.4 10.2 0.1 4.3 4 0 0 4 4 4 2 Cupin domain Kdo PF06293.9 EKX73441.1 - 0.0088 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKX73441.1 - 0.01 15.5 0.0 0.027 14.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EKX73441.1 - 0.042 13.1 0.1 1.7 7.9 0.0 2.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Metallophos PF00149.23 EKX73442.1 - 0.00032 20.1 0.2 0.00092 18.6 0.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKX73442.1 - 0.01 15.7 0.0 0.07 12.9 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HIT PF01230.18 EKX73443.1 - 9.8e-26 90.1 0.5 3e-25 88.6 0.1 1.8 1 1 1 2 2 2 1 HIT domain DcpS_C PF11969.3 EKX73443.1 - 4.4e-22 78.5 0.4 6.3e-22 77.9 0.3 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Peptidase_M48 PF01435.13 EKX73445.1 - 3.8e-39 134.5 0.1 5.5e-39 134.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF955 PF06114.8 EKX73445.1 - 0.014 15.1 0.1 0.08 12.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF955) DUF1144 PF06610.8 EKX73445.1 - 0.028 14.1 0.1 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1144) DUF1191 PF06697.7 EKX73445.1 - 0.19 10.4 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Proteasome PF00227.21 EKX73446.1 - 3.7e-44 150.2 0.3 4.5e-44 150.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EKX73446.1 - 3.6e-14 51.7 0.0 6.4e-14 50.9 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PGM_PMM_I PF02878.11 EKX73447.1 - 1.9e-11 43.6 0.0 3.1e-07 29.9 0.0 2.6 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 EKX73447.1 - 4.4e-08 33.0 0.0 9.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 EKX73447.1 - 0.00094 19.4 0.0 0.0027 17.9 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Longin PF13774.1 EKX73449.1 - 1.3e-11 43.8 0.0 2.1e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EKX73449.1 - 1.6e-08 33.9 0.8 3e-08 33.1 0.5 1.5 1 0 0 1 1 1 1 Synaptobrevin Imm23 PF15593.1 EKX73449.1 - 0.015 15.5 4.3 0.23 11.6 3.0 2.2 1 1 0 1 1 1 0 Immunity protein 23 Seryl_tRNA_N PF02403.17 EKX73449.1 - 0.083 12.9 0.5 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.6 EKX73449.1 - 0.69 9.8 2.6 1.3 8.8 1.4 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 EKX73449.1 - 1.1 9.0 5.5 3.9 7.2 2.3 2.2 2 1 0 2 2 2 0 Laminin Domain II TruD PF01142.13 EKX73450.1 - 1.4e-45 155.6 0.0 1.7e-43 148.7 0.0 3.4 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) MRP-L28 PF09812.4 EKX73451.1 - 0.00016 21.5 0.6 0.00016 21.5 0.4 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 YjeF_N PF03853.10 EKX73452.1 - 5.2e-32 110.7 0.0 6.5e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Bax1-I PF01027.15 EKX73453.1 - 7.4e-23 81.2 18.3 8.9e-23 80.9 12.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3043 PF11241.3 EKX73453.1 - 2.4 7.7 7.5 1.6 8.2 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) zf-rbx1 PF12678.2 EKX73454.1 - 3e-06 27.2 7.9 1.3e-05 25.1 4.9 2.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EKX73454.1 - 4e-06 26.5 8.2 2.6e-05 23.9 5.7 2.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EKX73454.1 - 0.00013 21.8 7.1 0.00013 21.8 4.9 3.4 3 0 0 3 3 3 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EKX73454.1 - 0.0007 19.3 6.1 0.0013 18.4 3.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 EKX73454.1 - 1.1 9.3 12.4 0.64 10.0 5.6 2.9 2 0 0 2 2 2 0 RING-like domain Form_Nir_trans PF01226.12 EKX73455.1 - 1.2e-58 197.9 13.5 1.4e-58 197.7 9.4 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter AAA PF00004.24 EKX73456.1 - 2.2e-36 124.9 0.1 3.9e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EKX73456.1 - 3e-05 23.5 1.1 0.031 13.6 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 EKX73456.1 - 6.6e-05 22.6 0.0 0.00027 20.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EKX73456.1 - 7.1e-05 22.7 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EKX73456.1 - 0.00017 21.5 0.0 0.0006 19.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EKX73456.1 - 0.00019 20.5 0.0 0.00051 19.1 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EKX73456.1 - 0.00042 21.1 0.1 0.0019 19.0 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EKX73456.1 - 0.00052 19.7 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EKX73456.1 - 0.00061 20.1 0.2 0.013 15.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EKX73456.1 - 0.0013 18.8 0.9 0.011 15.8 0.2 2.7 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 EKX73456.1 - 0.0037 16.0 0.0 0.0079 14.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_11 PF13086.1 EKX73456.1 - 0.0095 15.5 0.9 0.035 13.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 EKX73456.1 - 0.026 14.8 0.1 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.16 EKX73456.1 - 0.032 13.3 0.0 0.072 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EKX73456.1 - 0.04 13.3 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 EKX73456.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 EKX73456.1 - 0.066 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA_16 PF13191.1 EKX73456.1 - 0.084 12.8 0.1 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain SKI PF01202.17 EKX73456.1 - 0.096 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_28 PF13521.1 EKX73456.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 EKX73456.1 - 0.12 12.2 0.3 1.6 8.5 0.0 2.7 3 0 0 3 3 3 0 Torsin GBP PF02263.14 EKX73457.1 - 8.4e-06 25.0 0.1 2.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain zf-RanBP PF00641.13 EKX73458.1 - 1.6e-12 46.3 16.2 1.6e-06 27.0 1.5 2.1 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EKX73458.1 - 0.00054 19.7 8.6 0.00091 18.9 5.9 1.4 1 0 0 1 1 1 1 Double zinc ribbon Ribosomal_L37e PF01907.14 EKX73458.1 - 0.0076 16.0 9.9 0.29 10.9 1.9 2.4 1 1 1 2 2 2 2 Ribosomal protein L37e zf-P11 PF03854.9 EKX73458.1 - 0.0084 15.5 1.5 1.9 8.0 0.2 2.2 2 0 0 2 2 2 2 P-11 zinc finger Auto_anti-p27 PF06677.7 EKX73458.1 - 0.29 10.9 5.3 23 4.8 0.1 3.3 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF968 PF06147.6 EKX73458.1 - 0.36 10.7 1.5 7.5 6.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF968) C1_3 PF07649.7 EKX73458.1 - 0.46 10.5 5.5 11 6.1 0.1 3.1 3 0 0 3 3 3 0 C1-like domain C1_1 PF00130.17 EKX73458.1 - 0.63 9.8 5.2 0.36 10.5 0.7 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Mut7-C PF01927.11 EKX73458.1 - 0.75 9.7 3.1 1.1 9.2 2.2 1.3 1 0 0 1 1 1 0 Mut7-C RNAse domain Cytochrome_C7 PF14522.1 EKX73458.1 - 0.99 9.0 7.3 1.8 8.2 5.1 1.4 1 0 0 1 1 1 0 Cytochrome c7 DUF35_N PF12172.3 EKX73458.1 - 1.3 8.9 4.1 2 8.3 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HypA PF01155.14 EKX73458.1 - 3 7.5 5.5 5.5 6.7 3.8 1.5 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-HIT PF04438.11 EKX73458.1 - 5.2 6.7 8.4 22 4.8 0.8 3.1 3 0 0 3 3 3 0 HIT zinc finger Rubredoxin PF00301.15 EKX73458.1 - 6.1 6.7 8.9 29 4.6 0.0 3.3 2 1 1 3 3 3 0 Rubredoxin Rpr2 PF04032.11 EKX73458.1 - 6.7 6.6 8.0 28 4.6 5.4 1.9 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain XPG_I PF00867.13 EKX73459.1 - 2.8e-28 97.7 0.1 7.3e-28 96.4 0.1 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EKX73459.1 - 5e-27 94.1 0.0 1.4e-26 92.7 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EKX73459.1 - 5.9e-06 26.4 0.0 2.8e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.11 EKX73459.1 - 0.00023 20.5 0.0 0.0008 18.8 0.0 1.8 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain HHH_2 PF12826.2 EKX73459.1 - 0.011 15.5 0.0 0.051 13.4 0.0 2.2 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.1 EKX73459.1 - 0.056 13.6 0.0 0.75 10.0 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain Sigma70_r1_1 PF03979.9 EKX73459.1 - 0.16 11.9 5.1 0.88 9.5 0.0 3.6 4 0 0 4 4 4 0 Sigma-70 factor, region 1.1 DUF1233 PF06806.7 EKX73460.1 - 0.042 13.4 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Putative excisionase (DUF1233) CRAM_rpt PF07016.6 EKX73460.1 - 0.042 13.1 1.5 0.066 12.5 1.0 1.3 1 0 0 1 1 1 0 Cysteine-rich acidic integral membrane protein precursor Nipped-B_C PF12830.2 EKX73461.1 - 0.029 14.0 0.9 0.044 13.4 0.1 1.7 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Pkinase PF00069.20 EKX73462.1 - 1.9e-46 158.3 0.2 3.3e-46 157.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX73462.1 - 1e-22 80.4 0.1 1.5e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKX73462.1 - 3.2e-07 29.6 0.0 4.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EKX73462.1 - 0.00018 21.1 0.1 0.00049 19.7 0.1 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EKX73462.1 - 0.0019 17.9 0.0 0.0032 17.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EKX73462.1 - 0.0034 16.4 0.2 0.02 13.9 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_P_p30 PF01876.11 EKX73463.1 - 2.1e-15 56.2 0.0 3.9e-15 55.3 0.0 1.4 1 1 0 1 1 1 1 RNase P subunit p30 FAD_binding_3 PF01494.14 EKX73466.1 - 3.4e-49 167.8 0.0 1.7e-31 109.5 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.12 EKX73466.1 - 0.053 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Actin PF00022.14 EKX73468.1 - 9.4e-152 504.9 0.0 1.1e-151 504.7 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EKX73468.1 - 0.056 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Phosphodiest PF01663.17 EKX73468.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase PIG-S PF10510.4 EKX73469.1 - 7.6e-12 44.6 3.7 6.5e-11 41.6 1.3 2.4 2 1 0 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein DUF1654 PF07867.6 EKX73469.1 - 0.0074 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1654) Pro_isomerase PF00160.16 EKX73470.1 - 2.6e-47 160.8 0.8 4.6e-47 160.0 0.6 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.23 EKX73470.1 - 7.4e-31 106.0 0.0 1.7e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 EKX73470.1 - 1.8e-14 53.1 8.7 1.6e-08 34.0 1.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EKX73470.1 - 2.8e-07 29.9 2.4 0.0085 15.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EKX73470.1 - 0.00017 21.3 0.1 0.00026 20.7 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EKX73470.1 - 0.00055 19.4 8.8 0.015 14.8 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKX73470.1 - 0.049 13.5 1.2 0.38 10.6 0.2 2.4 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.1 EKX73470.1 - 0.094 13.4 4.3 0.35 11.6 2.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKX73470.1 - 0.097 13.3 0.8 0.39 11.4 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EKX73470.1 - 0.11 12.6 4.9 0.5 10.5 1.7 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EKX73470.1 - 0.13 12.1 0.9 1.6 8.7 0.2 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat CotJB PF12652.2 EKX73470.1 - 0.2 11.7 0.5 3.5 7.7 0.4 2.4 2 0 0 2 2 2 0 CotJB protein TPR_17 PF13431.1 EKX73470.1 - 0.2 11.9 2.1 2.9 8.3 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat MAM PF00629.18 EKX73471.1 - 0.0082 15.9 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 MAM domain DUF2450 PF10475.4 EKX73475.1 - 0.0001 21.3 0.1 0.00035 19.5 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) BING4CT PF08149.6 EKX73475.1 - 0.058 12.9 0.0 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 BING4CT (NUC141) domain AAA PF00004.24 EKX73477.1 - 4.8e-43 146.5 0.0 9.7e-43 145.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKX73477.1 - 8.3e-09 35.2 0.0 2.6e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EKX73477.1 - 6.3e-07 29.4 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EKX73477.1 - 3.2e-06 27.2 0.4 2.2e-05 24.5 0.3 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EKX73477.1 - 1.1e-05 25.6 0.2 0.00026 21.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKX73477.1 - 8.7e-05 23.3 0.1 0.00034 21.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EKX73477.1 - 9.7e-05 21.5 0.0 0.00018 20.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EKX73477.1 - 0.00017 21.2 0.0 0.0004 20.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EKX73477.1 - 0.00049 19.5 0.0 0.00093 18.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EKX73477.1 - 0.00079 19.3 0.3 0.0029 17.5 0.0 2.0 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 EKX73477.1 - 0.0011 17.7 0.0 0.0023 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_3 PF07726.6 EKX73477.1 - 0.0032 17.0 0.0 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EKX73477.1 - 0.0036 17.2 0.0 0.0091 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EKX73477.1 - 0.0042 16.9 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EKX73477.1 - 0.0043 16.1 0.0 0.0082 15.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KaiC PF06745.8 EKX73477.1 - 0.0069 15.5 0.2 0.027 13.5 0.0 2.0 3 0 0 3 3 3 1 KaiC AAA_18 PF13238.1 EKX73477.1 - 0.0072 16.6 0.0 0.023 15.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 EKX73477.1 - 0.0099 15.0 0.1 0.022 13.9 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EKX73477.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EKX73477.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EKX73477.1 - 0.016 14.6 0.1 0.086 12.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 EKX73477.1 - 0.018 14.6 0.0 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 EKX73477.1 - 0.025 13.8 0.0 0.08 12.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 EKX73477.1 - 0.026 13.9 0.0 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EKX73477.1 - 0.036 12.9 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EKX73477.1 - 0.04 12.8 0.0 0.064 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) V-SNARE PF05008.10 EKX73477.1 - 0.056 13.5 0.4 0.19 11.9 0.3 1.8 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus HR1 PF02185.11 EKX73477.1 - 0.06 13.0 3.0 0.23 11.2 2.1 2.0 1 1 0 1 1 1 0 Hr1 repeat Histone PF00125.19 EKX73477.1 - 0.072 13.2 0.1 0.2 11.7 0.0 1.8 2 0 0 2 2 1 0 Core histone H2A/H2B/H3/H4 Sigma54_activ_2 PF14532.1 EKX73477.1 - 0.075 13.0 0.0 0.19 11.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 EKX73477.1 - 0.1 12.1 0.1 0.22 11.0 0.0 1.7 2 1 0 2 2 1 0 AAA domain ABC_tran PF00005.22 EKX73477.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.9 1 1 0 1 1 1 0 ABC transporter THUMP PF02926.12 EKX73478.1 - 1.2e-10 41.3 0.8 1.4e-09 37.9 0.6 2.1 1 1 0 1 1 1 1 THUMP domain FYDLN_acid PF09538.5 EKX73478.1 - 0.06 13.9 3.6 0.094 13.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PP2C PF00481.16 EKX73479.1 - 1.8e-47 161.8 0.0 4.9e-47 160.4 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKX73479.1 - 2e-07 30.6 0.0 1.5e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKX73479.1 - 0.00099 18.8 0.0 0.0033 17.1 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Mak16 PF04874.9 EKX73479.1 - 1.5 8.9 9.6 5.3 7.1 1.0 2.6 2 0 0 2 2 2 0 Mak16 protein C-terminal region Tho2 PF11262.3 EKX73480.1 - 1.3e-82 277.2 0.7 1.3e-82 277.2 0.5 2.1 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EKX73480.1 - 3.7e-07 29.8 0.6 2.1e-06 27.4 0.2 2.5 2 0 0 2 2 2 1 Transcription- and export-related complex subunit FAINT PF04385.10 EKX73481.1 - 1.9e-05 24.3 0.8 0.033 14.0 0.0 3.1 2 2 1 4 4 4 2 Domain of unknown function, DUF529 Thr_dehydrat_C PF00585.13 EKX73481.1 - 0.093 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase FAINT PF04385.10 EKX73482.1 - 1.2e-10 41.0 0.2 2.6e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF2827 PF10933.3 EKX73482.1 - 0.024 13.1 0.1 0.1 11.0 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2827) EMA PF02488.10 EKX73482.1 - 0.099 12.1 0.0 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 Merozoite Antigen FAINT PF04385.10 EKX73485.1 - 1e-18 66.9 9.2 2.1e-06 27.4 0.1 4.6 4 0 0 4 4 4 4 Domain of unknown function, DUF529 GATA PF00320.22 EKX73485.1 - 0.0045 16.2 1.3 0.013 14.8 0.2 2.3 2 0 0 2 2 2 1 GATA zinc finger Fcf2 PF08698.6 EKX73486.1 - 3e-12 46.3 0.0 6.5e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Peptidase_C1 PF00112.18 EKX73487.1 - 9e-38 130.3 2.9 2.5e-37 128.8 2.0 1.8 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.6 EKX73487.1 - 0.00022 21.3 3.4 0.00043 20.4 0.0 3.1 3 1 1 4 4 4 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.10 EKX73487.1 - 0.091 11.2 1.5 0.26 9.7 0.8 1.8 1 1 1 2 2 2 0 Peptidase C1-like family ABC_tran PF00005.22 EKX73489.1 - 1.5e-34 119.2 0.1 3.1e-34 118.1 0.1 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EKX73489.1 - 1.5e-28 99.9 13.2 2.1e-28 99.4 9.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EKX73489.1 - 4.1e-07 29.4 2.3 1.6e-06 27.5 1.6 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EKX73489.1 - 3.3e-05 24.0 5.7 0.0013 18.7 4.0 2.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EKX73489.1 - 0.002 17.3 0.0 0.0049 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 EKX73489.1 - 0.0027 16.3 0.0 0.011 14.4 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_14 PF13173.1 EKX73489.1 - 0.0068 16.3 0.4 0.2 11.5 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EKX73489.1 - 0.016 14.7 0.0 0.055 13.0 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EKX73489.1 - 0.037 14.3 1.5 0.09 13.0 1.0 1.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EKX73489.1 - 0.052 14.0 0.1 0.21 12.1 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein T2SE PF00437.15 EKX73489.1 - 0.08 11.8 0.0 0.2 10.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein FAINT PF04385.10 EKX73490.1 - 2.3e-10 40.1 0.5 0.00032 20.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Bud13 PF09736.4 EKX73491.1 - 0.00038 20.7 0.7 0.00038 20.7 0.5 1.5 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex zf-CCCH PF00642.19 EKX73492.1 - 0.00022 20.8 0.7 0.00062 19.3 0.1 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FYVE PF01363.16 EKX73492.1 - 0.79 9.6 9.1 0.24 11.3 3.8 2.2 2 1 0 2 2 2 0 FYVE zinc finger EF-hand_7 PF13499.1 EKX73493.1 - 1.9e-06 27.8 1.1 3.1e-05 24.0 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EKX73493.1 - 0.0015 18.2 2.0 0.11 12.4 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain DUF148 PF02520.12 EKX73493.1 - 0.0021 17.8 1.6 0.081 12.7 1.1 2.3 1 1 0 1 1 1 1 Domain of unknown function DUF148 EF-hand_8 PF13833.1 EKX73493.1 - 0.0026 17.3 0.4 0.0074 15.8 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EKX73493.1 - 0.0033 16.6 0.7 0.066 12.5 0.2 2.6 2 0 0 2 2 2 1 EF hand FTA4 PF13093.1 EKX73493.1 - 0.0037 16.7 1.6 0.0049 16.3 1.1 1.2 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1978 PF09321.5 EKX73493.1 - 0.0081 15.6 3.1 0.6 9.5 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1978) TBPIP PF07106.8 EKX73493.1 - 0.015 14.8 0.3 0.015 14.8 0.2 1.6 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RapA_C PF12137.3 EKX73493.1 - 0.052 12.3 0.4 0.076 11.8 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Bacillus_HBL PF05791.6 EKX73493.1 - 0.068 12.5 0.9 0.15 11.4 0.6 1.5 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Syntaxin PF00804.20 EKX73493.1 - 0.092 12.9 1.2 0.11 12.6 0.1 1.8 2 0 0 2 2 2 0 Syntaxin FliD_C PF07195.7 EKX73493.1 - 0.14 11.4 2.8 0.31 10.2 0.3 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Syntaxin-6_N PF09177.6 EKX73493.1 - 0.26 11.7 2.2 2.4 8.6 0.6 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Erp_C PF06780.6 EKX73493.1 - 0.29 10.9 3.9 1.9 8.3 1.2 2.3 1 1 1 2 2 2 0 Erp protein C-terminus MIF4G_like_2 PF09090.6 EKX73493.1 - 0.77 8.9 4.8 0.81 8.8 1.0 2.0 1 1 0 2 2 2 0 MIF4G like FAINT PF04385.10 EKX73494.1 - 3.8e-06 26.6 0.1 0.0067 16.2 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX73494.1 - 0.00048 19.6 0.8 0.65 9.4 0.0 2.1 2 0 0 2 2 2 2 Merozoite Antigen ABC_tran PF00005.22 EKX73495.1 - 2.6e-09 37.4 0.0 4.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EKX73495.1 - 0.0016 18.4 0.2 0.0016 18.4 0.1 2.4 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EKX73495.1 - 0.0058 16.9 0.7 0.011 16.1 0.5 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EKX73495.1 - 0.0079 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EKX73495.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EKX73495.1 - 0.021 14.6 0.6 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Dynamin family AAA_29 PF13555.1 EKX73495.1 - 0.023 14.2 0.1 0.048 13.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EKX73495.1 - 0.15 11.4 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Hydrolase_3 PF08282.7 EKX73497.1 - 5e-40 137.6 0.0 6.3e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX73497.1 - 1.8e-09 37.2 0.0 5.6e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EKX73497.1 - 0.0037 17.4 0.1 0.0046 17.1 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase VBS PF08913.5 EKX73498.1 - 0.025 14.8 0.4 0.084 13.1 0.2 1.8 1 1 0 1 1 1 0 Vinculin Binding Site Vps5 PF09325.5 EKX73498.1 - 0.27 10.4 2.1 0.23 10.6 0.5 1.4 2 0 0 2 2 2 0 Vps5 C terminal like FAINT PF04385.10 EKX73500.1 - 7.7e-27 92.9 33.0 3.8e-09 36.2 1.4 8.4 7 2 1 8 8 8 7 Domain of unknown function, DUF529 Nucleoplasmin PF03066.10 EKX73503.1 - 0.018 14.5 1.2 0.024 14.1 0.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin S-antigen PF05756.6 EKX73503.1 - 0.048 13.6 1.0 0.089 12.7 0.7 1.5 1 0 0 1 1 1 0 S-antigen protein FAINT PF04385.10 EKX73503.1 - 0.13 12.1 1.9 0.92 9.3 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function, DUF529 BSP_II PF05432.6 EKX73503.1 - 0.69 9.1 7.6 0.9 8.7 5.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) ATP11 PF06644.6 EKX73504.1 - 1.6e-34 119.6 0.4 1.9e-34 119.3 0.3 1.0 1 0 0 1 1 1 1 ATP11 protein FAINT PF04385.10 EKX73505.1 - 1.1e-07 31.6 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 DUF4111 PF13427.1 EKX73506.1 - 0.011 15.5 0.1 0.037 13.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Yopt PF09467.5 EKX73506.1 - 0.019 14.8 0.1 0.11 12.2 0.1 2.3 1 1 0 1 1 1 0 Hypothetical protein Yopt Herpes_IE1 PF07340.6 EKX73506.1 - 0.031 12.7 2.3 0.23 9.8 0.0 2.3 2 0 0 2 2 2 0 Cytomegalovirus IE1 protein DUF641 PF04859.7 EKX73506.1 - 1.2 8.8 9.3 0.13 12.0 0.2 3.3 3 2 2 5 5 5 0 Plant protein of unknown function (DUF641) FAINT PF04385.10 EKX73508.1 - 2e-16 59.6 3.6 7.6e-05 22.4 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 EKX73508.1 - 0.00019 20.9 6.8 0.0019 17.7 1.6 2.7 1 1 2 3 3 3 2 Merozoite Antigen FAINT PF04385.10 EKX73510.1 - 3.1e-05 23.7 0.0 4.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73513.1 - 1.8e-07 30.9 0.4 3e-07 30.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function, DUF529 Baculo_RING PF05883.6 EKX73513.1 - 0.011 15.5 0.2 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain EMA PF02488.10 EKX73513.1 - 0.029 13.8 0.9 0.049 13.1 0.6 1.3 1 1 0 1 1 1 0 Merozoite Antigen FAINT PF04385.10 EKX73514.1 - 1.3e-13 50.5 1.3 6.9e-07 29.0 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function, DUF529 Glyco_hydro_32N PF00251.15 EKX73514.1 - 0.00086 18.7 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Gly-zipper_OmpA PF13436.1 EKX73515.1 - 1.6 8.4 4.0 3.7 7.2 2.8 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain FAINT PF04385.10 EKX73516.1 - 1.6e-16 59.8 0.0 1.5e-08 34.3 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 PyrI_C PF02748.10 EKX73517.1 - 0.16 11.4 0.6 0.38 10.2 0.4 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain SRPRB PF09439.5 EKX73519.1 - 1.2e-21 76.7 0.4 4.9e-21 74.7 0.1 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EKX73519.1 - 6.5e-10 38.5 0.0 8.8e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKX73519.1 - 9.3e-10 38.4 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EKX73519.1 - 6.6e-09 36.2 0.2 1.3e-08 35.3 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EKX73519.1 - 6.9e-07 28.8 0.1 0.00016 21.1 0.1 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Ras PF00071.17 EKX73519.1 - 5.3e-06 25.9 0.1 9.2e-06 25.1 0.0 1.4 1 1 0 1 1 1 1 Ras family MobB PF03205.9 EKX73519.1 - 0.004 16.8 0.0 0.0075 15.9 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EKX73519.1 - 0.015 14.8 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EKX73519.1 - 0.046 13.5 0.2 8.3 6.1 0.0 2.2 1 1 1 2 2 2 0 Dynamin family AAA_16 PF13191.1 EKX73519.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain FAINT PF04385.10 EKX73520.1 - 0.014 15.2 0.2 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73523.1 - 1.3e-14 53.8 0.9 4e-05 23.3 0.0 4.5 4 1 0 4 4 4 3 Domain of unknown function, DUF529 Curto_V3 PF07436.6 EKX73527.1 - 0.086 12.9 0.1 8 6.6 0.0 2.6 2 0 0 2 2 2 0 Curtovirus V3 protein FAINT PF04385.10 EKX73528.1 - 2.6e-15 56.0 6.1 2.7e-08 33.5 0.1 4.5 5 0 0 5 5 5 3 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73529.1 - 9.1e-12 44.6 0.0 3.3e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX73529.1 - 2.7e-05 23.7 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 2 Merozoite Antigen FAINT PF04385.10 EKX73530.1 - 0.0046 16.7 0.2 0.012 15.3 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function, DUF529 Hydrolase_3 PF08282.7 EKX73534.1 - 4.3e-31 108.4 0.1 6.8e-26 91.3 0.0 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX73534.1 - 0.00054 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase FAINT PF04385.10 EKX73534.1 - 0.0022 17.7 3.9 0.034 14.0 0.0 3.7 2 1 0 2 2 2 1 Domain of unknown function, DUF529 Ub-Mut7C PF14451.1 EKX73534.1 - 0.055 12.9 0.1 30 4.2 0.0 3.3 3 0 0 3 3 3 0 Mut7-C ubiquitin Ribosomal_S14 PF00253.16 EKX73536.1 - 2.2e-16 58.9 0.1 3.8e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF1947 PF09183.5 EKX73537.1 - 0.25 11.1 4.7 1.9 8.2 0.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1947) FAINT PF04385.10 EKX73539.1 - 8.4e-08 31.9 0.0 8.4e-08 31.9 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73540.1 - 1e-20 73.3 4.5 7.5e-10 38.5 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Pyr_redox PF00070.22 EKX73541.1 - 1.1e-05 25.7 0.3 0.093 13.1 0.0 3.8 4 1 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKX73541.1 - 1.3e-05 25.0 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKX73541.1 - 6.7e-05 22.8 0.0 0.042 13.7 0.0 3.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EKX73541.1 - 7.7e-05 21.9 0.0 0.002 17.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EKX73541.1 - 0.0005 19.8 0.0 0.0015 18.3 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EKX73541.1 - 0.0074 16.3 0.0 2.3 8.2 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKX73541.1 - 0.017 14.0 0.0 0.97 8.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.1 EKX73541.1 - 0.029 13.3 0.0 7.3 5.4 0.0 2.7 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EKX73541.1 - 0.031 13.3 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EKX73541.1 - 0.034 12.7 0.0 0.23 10.0 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 EKX73541.1 - 0.064 11.7 0.1 0.14 10.6 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein DUF498 PF04430.9 EKX73541.1 - 0.13 11.7 0.0 20 4.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) Coatomer_WDAD PF04053.9 EKX73542.1 - 0.045 12.5 0.0 0.093 11.5 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region Death PF00531.17 EKX73543.1 - 0.075 12.8 0.2 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Death domain FAINT PF04385.10 EKX73544.1 - 3.8e-10 39.4 0.0 8e-07 28.8 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function, DUF529 MAD PF05557.8 EKX73544.1 - 0.15 10.0 0.0 0.21 9.6 0.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF167 PF02594.11 EKX73547.1 - 0.042 13.7 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 FAINT PF04385.10 EKX73548.1 - 7.7e-11 41.6 0.3 7.6e-06 25.6 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 RNA_bind PF08675.6 EKX73548.1 - 0.038 13.9 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA binding domain EMA PF02488.10 EKX73548.1 - 0.1 12.0 0.9 0.18 11.2 0.5 1.5 1 1 1 2 2 2 0 Merozoite Antigen DNA_pol_alpha_N PF12254.3 EKX73548.1 - 0.29 10.9 2.1 0.56 10.0 1.5 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal SHOCT PF09851.4 EKX73548.1 - 0.32 10.5 4.2 0.55 9.7 2.9 1.4 1 0 0 1 1 1 0 Short C-terminal domain Aldo_ket_red PF00248.16 EKX73549.1 - 8.9e-62 208.4 0.0 1e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAINT PF04385.10 EKX73550.1 - 1.5e-17 63.2 0.0 1.4e-10 40.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73551.1 - 1.8e-07 30.9 0.3 0.00019 21.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF4463 PF14703.1 EKX73551.1 - 0.085 13.3 0.1 0.25 11.8 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) FAINT PF04385.10 EKX73552.1 - 1.2e-12 47.4 2.2 0.00012 21.8 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73553.1 - 4.1e-10 39.3 0.1 0.00089 19.0 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73554.1 - 1.2e-12 47.4 0.0 7.4e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF4343 PF14243.1 EKX73554.1 - 0.096 12.5 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) PP2C PF00481.16 EKX73556.1 - 2e-64 217.4 0.0 4.9e-51 173.5 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EKX73556.1 - 0.00069 19.3 0.0 0.0059 16.3 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) RNase_T PF00929.19 EKX73556.1 - 0.094 12.9 0.0 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 Exonuclease Cuticle_2 PF08184.6 EKX73558.1 - 0.054 13.2 2.8 2.6 7.9 0.0 3.0 3 0 0 3 3 3 0 Cuticle protein 7 isoform family PIG-F PF06699.6 EKX73559.1 - 3.7e-09 36.7 1.4 4.9e-09 36.4 0.9 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F LysE PF01810.13 EKX73559.1 - 0.079 12.2 8.1 0.25 10.5 2.9 2.8 2 1 0 2 2 2 0 LysE type translocator Ninjurin PF04923.7 EKX73559.1 - 0.69 9.6 5.0 0.44 10.2 0.2 2.4 2 1 0 2 2 2 0 Ninjurin DUF3278 PF11683.3 EKX73559.1 - 1.1 9.2 6.6 0.11 12.4 0.7 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) ETRAMP PF09716.5 EKX73559.1 - 1.4 8.9 5.8 37 4.3 3.3 3.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FAINT PF04385.10 EKX73560.1 - 6e-05 22.8 0.8 9.1e-05 22.2 0.1 1.7 2 1 0 2 2 2 1 Domain of unknown function, DUF529 TBPIP PF07106.8 EKX73562.1 - 0.075 12.5 14.7 0.047 13.2 5.1 2.6 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Allexi_40kDa PF05549.6 EKX73562.1 - 0.09 12.0 9.0 0.21 10.8 0.7 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein Sigma70_ner PF04546.8 EKX73562.1 - 0.16 11.5 10.4 0.28 10.7 7.0 1.6 1 1 0 1 1 1 0 Sigma-70, non-essential region DUF2959 PF11172.3 EKX73562.1 - 0.31 10.7 11.1 0.13 11.9 1.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2959) NYD-SP28_assoc PF14775.1 EKX73562.1 - 0.57 9.9 9.3 0.25 11.0 2.5 2.9 3 0 0 3 3 3 0 Sperm tail C-terminal domain Phage_lysis PF03245.8 EKX73562.1 - 0.58 10.1 7.1 0.47 10.4 3.3 2.0 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein IncA PF04156.9 EKX73562.1 - 6 6.4 12.7 11 5.5 6.3 2.3 2 0 0 2 2 2 0 IncA protein Metallophos PF00149.23 EKX73563.1 - 3.9e-41 140.6 0.2 5.3e-41 140.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Urm1 PF09138.6 EKX73564.1 - 2.4e-27 94.9 0.0 3.5e-27 94.3 0.0 1.3 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) KASH PF10541.4 EKX73565.1 - 0.069 12.9 2.0 0.13 12.0 1.4 1.4 1 0 0 1 1 1 0 Nuclear envelope localisation domain DUF4013 PF13197.1 EKX73565.1 - 0.078 12.3 0.2 0.078 12.3 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4013) IncA PF04156.9 EKX73565.1 - 5 6.6 12.8 0.13 11.8 1.6 2.1 2 0 0 2 2 2 0 IncA protein Guanylate_cyc PF00211.15 EKX73567.1 - 6.9e-81 270.0 0.1 2.4e-45 154.1 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain E1-E2_ATPase PF00122.15 EKX73567.1 - 1.1e-16 60.5 0.2 5.5e-16 58.2 0.1 2.2 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EKX73567.1 - 2.4e-11 44.1 0.0 8e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKX73567.1 - 2.1e-08 34.8 0.0 1.8e-05 25.2 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKX73567.1 - 6e-05 22.9 0.1 0.00022 21.1 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EKX73567.1 - 0.00015 21.4 1.3 0.00037 20.1 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4191 PF13829.1 EKX73567.1 - 0.3 10.1 3.7 1.2 8.1 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) PspB PF06667.7 EKX73567.1 - 1.3 8.9 6.0 0.63 10.0 0.0 3.0 3 0 0 3 3 3 0 Phage shock protein B Adaptin_N PF01602.15 EKX73568.1 - 0.0076 14.6 0.2 0.0076 14.6 0.2 2.6 2 1 0 2 2 2 1 Adaptin N terminal region dUTPase_2 PF08761.6 EKX73568.1 - 0.014 15.4 0.3 0.077 13.0 0.0 2.3 2 0 0 2 2 2 0 dUTPase VHS PF00790.14 EKX73568.1 - 0.034 13.7 0.2 0.28 10.8 0.0 2.3 2 0 0 2 2 2 0 VHS domain HEAT PF02985.17 EKX73568.1 - 0.099 12.7 0.2 15 6.0 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat ELMO_CED12 PF04727.8 EKX73569.1 - 7.6e-33 113.4 1.0 1.5e-32 112.4 0.3 1.7 1 1 1 2 2 2 1 ELMO/CED-12 family DUF3417 PF11897.3 EKX73569.1 - 0.027 14.4 0.8 0.063 13.2 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3417) WD40 PF00400.27 EKX73570.1 - 5.1e-08 32.5 0.2 0.00057 19.6 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat CBF PF03914.12 EKX73572.1 - 5.6e-20 71.4 2.1 3.4e-19 68.8 0.3 2.6 2 0 0 2 2 2 1 CBF/Mak21 family CLASP_N PF12348.3 EKX73572.1 - 0.013 14.9 0.4 0.013 14.9 0.3 2.2 2 0 0 2 2 2 0 CLASP N terminal MMR_HSR1 PF01926.18 EKX73573.1 - 3.3e-11 43.1 0.0 2.7e-10 40.2 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase NOG1 PF06858.9 EKX73573.1 - 2.4e-08 33.7 0.2 3.1e-06 26.9 0.0 3.3 4 0 0 4 4 4 1 Nucleolar GTP-binding protein 1 (NOG1) GTP_EFTU PF00009.22 EKX73573.1 - 0.00059 19.3 0.0 0.0018 17.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EKX73573.1 - 0.0067 16.9 0.4 0.1 13.1 0.1 2.7 1 1 1 2 2 2 1 Miro-like protein Arch_ATPase PF01637.13 EKX73573.1 - 0.012 15.3 0.1 4.5 6.9 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase MobB PF03205.9 EKX73573.1 - 0.012 15.2 1.3 0.016 14.9 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 EKX73573.1 - 0.077 12.2 0.0 0.66 9.2 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B FAINT PF04385.10 EKX73575.1 - 3.1e-11 42.9 0.2 4.5e-11 42.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 EMA PF02488.10 EKX73575.1 - 0.071 12.5 1.3 0.093 12.1 0.9 1.1 1 0 0 1 1 1 0 Merozoite Antigen CG-1 PF03859.11 EKX73575.1 - 0.095 12.2 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 CG-1 domain zf-Mss51 PF13824.1 EKX73575.1 - 0.095 12.5 0.2 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 tRNA-synt_1e PF01406.14 EKX73576.1 - 5.3e-121 403.3 0.1 9.6e-121 402.5 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EKX73576.1 - 6.1e-13 48.1 1.4 4.1e-07 29.0 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EKX73576.1 - 4.4e-05 21.6 0.0 8.9e-05 20.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.16 EKX73576.1 - 0.017 13.8 0.4 0.053 12.1 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.13 EKX73576.1 - 0.036 12.7 0.1 0.14 10.8 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (K) Alba PF01918.16 EKX73579.1 - 3.1e-09 36.2 0.3 4.3e-09 35.8 0.2 1.2 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 EKX73579.1 - 0.0036 16.9 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P NOT2_3_5 PF04153.13 EKX73580.1 - 3.5e-33 114.3 3.7 4.2e-33 114.0 2.5 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family 4HBT PF03061.17 EKX73584.1 - 6.3e-06 26.2 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily CHCH PF06747.8 EKX73589.1 - 3.2 7.7 11.0 0.93 9.4 4.4 2.5 2 1 0 2 2 2 0 CHCH domain DUF1947 PF09183.5 EKX73590.1 - 0.67 9.7 6.2 0.43 10.3 0.4 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1947) FAINT PF04385.10 EKX73591.1 - 2e-12 46.7 0.4 4.4e-07 29.6 0.2 3.2 3 0 0 3 3 3 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX73591.1 - 0.002 17.6 2.4 0.84 9.0 0.2 2.1 2 0 0 2 2 2 2 Merozoite Antigen Phospho_p8 PF10195.4 EKX73591.1 - 2.2 8.2 7.4 2 8.3 0.5 3.1 3 0 0 3 3 3 0 DNA-binding nuclear phosphoprotein p8 Abhydrolase_6 PF12697.2 EKX73592.1 - 2.2e-09 37.5 0.0 4.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FAINT PF04385.10 EKX73592.1 - 2.7e-09 36.7 1.2 4e-06 26.5 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Abhydrolase_5 PF12695.2 EKX73592.1 - 7.4e-06 25.7 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX73592.1 - 0.00025 20.8 0.1 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase DUF900 PF05990.7 EKX73592.1 - 0.044 13.0 0.0 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) LIP PF03583.9 EKX73593.1 - 5.9e-06 25.6 0.0 6.1e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 EKX73593.1 - 0.00028 20.1 0.0 0.00032 19.9 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EKX73593.1 - 0.0017 18.2 0.0 0.0021 17.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EKX73593.1 - 0.024 14.0 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EKX73593.1 - 0.047 13.4 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family CS PF04969.11 EKX73594.1 - 7.9e-16 58.3 0.1 1.1e-15 57.8 0.1 1.2 1 0 0 1 1 1 1 CS domain DUF619 PF04768.8 EKX73596.1 - 0.03 13.7 0.2 0.06 12.7 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF619) DUF3449 PF11931.3 EKX73599.1 - 1.5e-76 256.3 1.2 3.3e-76 255.1 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EKX73599.1 - 4.8e-05 22.8 0.6 0.00016 21.1 0.4 1.9 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain EMA PF02488.10 EKX73600.1 - 0.021 14.3 3.1 0.41 10.0 2.0 2.4 1 1 1 2 2 2 0 Merozoite Antigen DUF3228 PF11539.3 EKX73600.1 - 0.039 13.0 0.1 0.087 11.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3228) FAINT PF04385.10 EKX73601.1 - 6.5e-13 48.3 1.1 3.2e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX73601.1 - 0.064 12.7 0.4 0.094 12.1 0.3 1.1 1 0 0 1 1 1 0 Merozoite Antigen PLAC9 PF15205.1 EKX73602.1 - 0.021 15.0 1.7 2.9 8.2 0.0 3.2 3 1 0 3 3 3 0 Placenta-specific protein 9 FAINT PF04385.10 EKX73603.1 - 1.9e-05 24.4 0.2 1.9e-05 24.4 0.2 3.1 2 1 1 3 3 3 2 Domain of unknown function, DUF529 NADH_oxidored PF08040.6 EKX73606.1 - 0.07 12.7 0.3 3.5 7.3 0.0 2.8 2 0 0 2 2 2 0 MNLL subunit FAINT PF04385.10 EKX73607.1 - 0.0002 21.1 0.0 0.26 11.1 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73608.1 - 1.5e-16 59.9 3.2 0.00014 21.6 0.0 3.7 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 EKX73608.1 - 3.8e-06 26.5 3.7 0.039 13.4 1.2 2.1 2 0 0 2 2 2 2 Merozoite Antigen CbbQ_C PF08406.5 EKX73608.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal DUF3488 PF11992.3 EKX73609.1 - 0.14 10.7 2.5 0.17 10.5 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Fumerase_C PF05683.7 EKX73611.1 - 2.2e-75 252.2 0.0 5e-75 251.1 0.0 1.6 2 0 0 2 2 2 1 Fumarase C-terminus Fumerase PF05681.9 EKX73611.1 - 2e-72 243.5 0.0 2.9e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) B2-adapt-app_C PF09066.5 EKX73611.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain DUF1510 PF07423.6 EKX73612.1 - 1.1 8.6 13.7 1.9 7.8 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Fumerase PF05681.9 EKX73613.1 - 1.3e-07 30.9 0.0 1.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) FTH PF01827.22 EKX73613.1 - 0.042 13.4 0.2 0.18 11.4 0.1 1.9 1 1 0 1 1 1 0 FTH domain DUF2252 PF10009.4 EKX73615.1 - 0.055 12.3 0.0 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF1628 PF07790.6 EKX73616.1 - 0.013 16.2 0.9 0.024 15.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) DUF1312 PF07009.6 EKX73616.1 - 0.035 13.9 0.2 0.13 12.1 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1312) DUF1923 PF09083.5 EKX73616.1 - 0.038 13.4 1.0 4.4 6.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) CRAL_TRIO_2 PF13716.1 EKX73616.1 - 0.063 13.1 0.1 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF2567 PF10821.3 EKX73616.1 - 0.068 12.6 0.1 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) Spore_III_AF PF09581.5 EKX73616.1 - 0.3 10.9 5.2 0.59 9.9 3.4 1.8 1 1 1 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) FAINT PF04385.10 EKX73617.1 - 6.7e-12 45.0 9.4 2.1e-05 24.2 0.5 4.6 4 0 0 4 4 4 3 Domain of unknown function, DUF529 Nucleoporin_FG PF13634.1 EKX73618.1 - 0.0033 17.6 10.0 0.0066 16.6 6.9 1.4 1 1 0 1 1 1 1 Nucleoporin FG repeat region FAINT PF04385.10 EKX73624.1 - 2.2e-10 40.2 0.9 1.4e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF4591 PF15261.1 EKX73624.1 - 0.017 15.4 0.9 0.029 14.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) Mito_fiss_reg PF05308.6 EKX73624.1 - 0.076 12.3 3.6 0.14 11.5 2.5 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator FAINT PF04385.10 EKX73625.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Ashwin PF15323.1 EKX73625.1 - 0.092 12.7 2.8 0.12 12.3 1.9 1.2 1 0 0 1 1 1 0 Developmental protein Pap_E4 PF02711.9 EKX73625.1 - 1.7 9.5 4.0 0.92 10.3 0.9 1.9 1 1 1 2 2 2 0 E4 protein G-patch_2 PF12656.2 EKX73626.1 - 2.1e-12 46.7 0.8 5.7e-12 45.3 0.6 1.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF3252 PF11623.3 EKX73626.1 - 0.044 13.1 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3252) GCS PF03074.11 EKX73627.1 - 2.3e-89 300.0 1.8 3.4e-89 299.5 1.3 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase Siva PF05458.7 EKX73627.1 - 0.052 13.1 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) HTS PF04204.11 EKX73627.1 - 0.087 11.5 0.1 0.21 10.2 0.0 1.6 2 0 0 2 2 2 0 Homoserine O-succinyltransferase CAP PF00188.21 EKX73629.1 - 0.007 16.8 3.9 0.043 14.2 0.0 3.0 3 0 0 3 3 3 1 Cysteine-rich secretory protein family HCV_NS5a_C PF12941.2 EKX73629.1 - 0.26 10.8 8.5 0.23 11.0 2.8 2.2 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region PAZ PF02170.17 EKX73631.1 - 0.027 13.7 5.3 0.051 12.8 0.1 2.2 2 0 0 2 2 2 0 PAZ domain Zn-ribbon_8 PF09723.5 EKX73631.1 - 0.11 12.5 0.4 0.2 11.6 0.3 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DUF3452 PF11934.3 EKX73633.1 - 0.021 14.1 1.1 2.4 7.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) Sec20 PF03908.8 EKX73633.1 - 0.084 12.5 0.8 2.3 7.9 0.0 2.6 1 1 1 2 2 2 0 Sec20 SIT PF15330.1 EKX73633.1 - 0.087 12.9 0.5 0.19 11.8 0.4 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF885 PF05960.6 EKX73633.1 - 0.1 11.7 0.3 0.12 11.4 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) IncA PF04156.9 EKX73633.1 - 3.9 7.0 13.9 35 3.9 8.1 2.6 1 1 1 2 2 2 0 IncA protein FAINT PF04385.10 EKX73634.1 - 0.00069 19.4 10.2 0.0023 17.7 1.6 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73635.1 - 1.2e-10 41.0 0.3 4.1e-05 23.3 0.0 2.8 2 2 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73636.1 - 4.8e-05 23.1 0.0 0.0052 16.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73637.1 - 8.9e-48 160.0 12.9 5.1e-05 23.0 0.2 9.6 9 0 0 9 9 9 9 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73638.1 - 1.1e-15 57.2 5.3 5.4e-05 22.9 0.0 4.2 4 0 0 4 4 4 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX73638.1 - 1.6e-12 47.7 0.0 2.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX73638.1 - 9.7e-09 35.1 0.0 2.1e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family EMA PF02488.10 EKX73638.1 - 5.1e-08 32.6 0.0 9.7e-05 21.9 0.0 2.5 1 1 1 2 2 2 2 Merozoite Antigen Hydrolase_4 PF12146.3 EKX73638.1 - 3e-06 26.9 0.1 8.3e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase LIP PF03583.9 EKX73638.1 - 0.00029 20.1 0.0 0.00046 19.4 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 EKX73638.1 - 0.0012 18.1 0.0 0.0035 16.5 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family FAINT PF04385.10 EKX73641.1 - 1.6e-24 85.5 0.2 3.2e-08 33.2 0.0 3.3 3 0 0 3 3 3 3 Domain of unknown function, DUF529 EMA PF02488.10 EKX73641.1 - 3.3e-05 23.4 1.3 0.095 12.1 0.0 3.3 3 1 1 4 4 4 2 Merozoite Antigen DUF605 PF04652.11 EKX73641.1 - 0.071 12.4 20.6 0.1 11.9 14.3 1.1 1 0 0 1 1 1 0 Vta1 like FAINT PF04385.10 EKX73645.1 - 1.8e-06 27.6 0.1 1.8e-06 27.6 0.1 3.6 3 1 0 3 3 3 1 Domain of unknown function, DUF529 EMA PF02488.10 EKX73645.1 - 0.013 15.0 1.2 0.013 15.0 0.8 3.0 4 0 0 4 4 4 0 Merozoite Antigen FAINT PF04385.10 EKX73646.1 - 1.2e-13 50.6 1.0 0.0003 20.5 0.0 4.0 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX73646.1 - 5.5e-12 46.0 0.0 1.3e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX73646.1 - 8.8e-10 38.3 0.1 1.6e-07 31.0 0.1 3.1 3 0 0 3 3 3 1 Putative lysophospholipase EMA PF02488.10 EKX73646.1 - 1.7e-07 31.0 2.9 0.0023 17.4 0.1 3.8 2 2 1 3 3 3 2 Merozoite Antigen Abhydrolase_5 PF12695.2 EKX73646.1 - 2.7e-05 23.9 0.0 7.9e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family AMA-1 PF02430.10 EKX73647.1 - 2.3e-139 465.3 3.8 2.4e-138 461.9 2.6 2.1 1 1 0 1 1 1 1 Apical membrane antigen 1 FAINT PF04385.10 EKX73648.1 - 5.6e-11 42.1 0.0 1.6e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Cut12 PF11500.3 EKX73648.1 - 0.011 15.4 0.6 4.6 6.9 0.1 2.6 2 1 0 2 2 2 0 Spindle pole body formation-associated protein EMA PF02488.10 EKX73648.1 - 0.012 15.0 0.5 0.027 13.9 0.3 1.6 1 1 0 1 1 1 0 Merozoite Antigen BRX_N PF13713.1 EKX73650.1 - 0.028 13.8 0.1 0.058 12.8 0.1 1.6 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain HATPase_c_4 PF13749.1 EKX73651.1 - 0.059 13.1 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal Syntaxin PF00804.20 EKX73653.1 - 0.12 12.4 0.8 0.51 10.5 0.2 1.9 2 0 0 2 2 2 0 Syntaxin RTTN_N PF14726.1 EKX73653.1 - 0.24 11.9 3.2 0.31 11.6 0.2 2.4 3 0 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning FAINT PF04385.10 EKX73654.1 - 2e-12 46.7 1.6 0.0057 16.4 0.0 3.6 3 0 0 3 3 3 3 Domain of unknown function, DUF529 ATP-cone PF03477.11 EKX73655.1 - 0.058 13.8 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 ATP cone domain RRM_6 PF14259.1 EKX73656.1 - 2.7e-12 46.4 0.0 7.2e-12 45.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.21 EKX73656.1 - 4.7e-12 45.8 0.2 2e-11 43.8 0.0 2.2 3 0 0 3 3 3 1 FHA domain RRM_1 PF00076.17 EKX73656.1 - 7.9e-12 44.6 0.1 3.1e-11 42.7 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1768 PF08719.6 EKX73656.1 - 1.6e-09 37.6 0.0 3.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_5 PF13893.1 EKX73656.1 - 6.5e-08 32.3 0.1 3.2e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKX73656.1 - 0.00017 21.2 0.0 0.00055 19.6 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF2071 PF09844.4 EKX73656.1 - 0.064 12.6 0.6 0.11 11.8 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) FAINT PF04385.10 EKX73658.1 - 1.7e-06 27.7 0.9 1.7e-06 27.7 0.6 1.8 2 1 0 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73659.1 - 4.3e-18 64.9 4.3 0.0056 16.5 0.0 5.9 5 1 0 5 5 5 4 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73661.1 - 2.4e-44 149.0 25.9 7.1e-06 25.7 0.1 9.6 9 0 0 9 9 9 8 Domain of unknown function, DUF529 BING4CT PF08149.6 EKX73661.1 - 0.036 13.5 0.0 0.13 11.7 0.0 1.9 1 0 0 1 1 1 0 BING4CT (NUC141) domain FAINT PF04385.10 EKX73662.1 - 2e-11 43.5 5.2 0.00057 19.6 0.1 3.5 3 0 0 3 3 3 3 Domain of unknown function, DUF529 Collagen PF01391.13 EKX73664.1 - 8.9 5.9 14.6 0.71 9.4 5.2 2.5 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) RNA_pol_Rpc34 PF05158.7 EKX73665.1 - 1e-33 116.9 3.5 1.4e-30 106.5 2.4 2.4 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit Gelsolin PF00626.17 EKX73665.1 - 0.12 12.0 0.1 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Gelsolin repeat Atracotoxin PF05353.6 EKX73666.1 - 0.018 14.8 0.7 0.059 13.2 0.5 1.8 1 0 0 1 1 1 0 Delta Atracotoxin DUF2583 PF10762.4 EKX73666.1 - 1.1 9.4 5.8 1.9 8.6 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) RecA PF00154.16 EKX73667.1 - 0.084 11.9 0.1 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein DUF2847 PF11009.3 EKX73667.1 - 0.14 11.7 0.3 0.3 10.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) FAINT PF04385.10 EKX73668.1 - 0.0094 15.7 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73669.1 - 0.00048 19.9 0.2 0.0011 18.8 0.1 1.7 1 1 1 2 2 2 1 Domain of unknown function, DUF529 ChuX_HutX PF06228.8 EKX73669.1 - 0.089 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX FAINT PF04385.10 EKX73670.1 - 4.2e-20 71.3 18.6 6.2e-06 25.9 0.2 4.8 4 0 0 4 4 4 4 Domain of unknown function, DUF529 Laminin_II PF06009.7 EKX73670.1 - 0.63 9.7 7.7 2.2 8.0 0.3 3.9 3 1 1 4 4 4 0 Laminin Domain II Ribonuc_2-5A PF06479.7 EKX73673.1 - 0.059 13.2 0.5 6 6.7 0.0 2.6 1 1 1 2 2 2 0 Ribonuclease 2-5A HD_4 PF13328.1 EKX73673.1 - 0.062 13.0 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 HD domain HisKA_3 PF07730.8 EKX73673.1 - 0.081 13.2 1.9 0.82 10.0 0.1 2.8 2 0 0 2 2 2 0 Histidine kinase HrpB2 PF09487.5 EKX73673.1 - 0.095 12.8 1.3 0.36 11.0 0.3 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) DUF1664 PF07889.7 EKX73673.1 - 0.49 10.1 3.5 1 9.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 EKX73673.1 - 1.6 8.2 7.5 1.1 8.8 1.8 2.3 2 0 0 2 2 2 0 IncA protein SPOUT_MTase PF02590.12 EKX73673.1 - 1.6 8.3 5.9 4.5 6.9 0.0 2.9 2 1 1 3 3 3 0 Predicted SPOUT methyltransferase RRF PF01765.14 EKX73673.1 - 8.9 5.7 7.9 1.1 8.6 0.7 2.5 2 1 1 3 3 3 0 Ribosome recycling factor FAINT PF04385.10 EKX73674.1 - 3e-15 55.8 0.8 8.2e-10 38.3 0.1 2.5 2 1 0 2 2 2 2 Domain of unknown function, DUF529 AviRa PF11599.3 EKX73674.1 - 0.17 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa OST3_OST6 PF04756.8 EKX73676.1 - 0.013 15.1 3.1 0.1 12.1 2.1 2.1 1 1 0 1 1 1 0 OST3 / OST6 family FAINT PF04385.10 EKX73678.1 - 1.8e-17 62.9 4.0 6.7e-08 32.2 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function, DUF529 DNA_pol3_delt_C PF14840.1 EKX73678.1 - 0.12 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term Ribosomal_S25 PF03297.10 EKX73679.1 - 2.3e-38 130.4 5.5 2.5e-38 130.3 3.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR PF01047.17 EKX73679.1 - 0.049 13.3 0.2 0.085 12.5 0.1 1.3 1 0 0 1 1 1 0 MarR family MotA_activ PF09114.5 EKX73679.1 - 0.097 12.4 0.4 0.13 11.9 0.3 1.2 1 0 0 1 1 1 0 Transcription factor MotA, activation domain DUF3516 PF12029.3 EKX73679.1 - 0.11 11.2 0.3 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) HTH_24 PF13412.1 EKX73679.1 - 0.15 11.5 0.7 0.23 10.8 0.5 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DHDPS PF00701.17 EKX73680.1 - 0.1 11.1 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family F5_F8_type_C PF00754.20 EKX73680.1 - 1.3 8.8 4.4 1.3 8.8 0.6 2.4 1 1 1 2 2 2 0 F5/8 type C domain FAINT PF04385.10 EKX73680.1 - 8.6 6.2 8.8 7 6.5 3.6 2.5 2 1 0 2 2 2 0 Domain of unknown function, DUF529 Ribosomal_L1 PF00687.16 EKX73681.1 - 8.5e-13 48.1 0.1 2.5e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MRL1 PF13003.2 EKX73681.1 - 0.0073 16.1 0.1 0.04 13.7 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein L1 zf-RING_2 PF13639.1 EKX73684.1 - 9.3e-11 41.3 11.0 9.3e-11 41.3 7.6 2.7 4 0 0 4 4 2 1 Ring finger domain zf-rbx1 PF12678.2 EKX73684.1 - 1.5e-06 28.2 10.2 5.4e-06 26.4 7.1 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EKX73684.1 - 1.6e-05 24.4 12.9 2e-05 24.1 6.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKX73684.1 - 2.4e-05 23.8 6.9 2.4e-05 23.8 4.8 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKX73684.1 - 5.6e-05 23.0 13.7 0.00011 22.1 7.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKX73684.1 - 0.0015 18.1 9.6 0.0015 18.1 6.6 2.4 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EKX73684.1 - 0.0084 15.9 12.8 0.021 14.7 6.1 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EKX73684.1 - 0.021 14.5 4.1 0.068 12.9 2.8 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EKX73684.1 - 0.083 12.7 7.4 0.84 9.5 5.1 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EKX73684.1 - 0.13 12.2 8.6 1.2 9.1 6.0 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EKX73684.1 - 1.2 8.9 6.9 4.9 6.9 4.8 2.1 1 0 0 1 1 1 0 RING-type zinc-finger DUF869 PF05911.6 EKX73687.1 - 0.12 10.5 0.1 0.14 10.3 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Nrap PF03813.9 EKX73688.1 - 2.3e-54 184.3 0.1 1.9e-53 181.3 0.1 2.2 1 1 0 1 1 1 1 Nrap protein Adeno_hexon_C PF03678.9 EKX73688.1 - 0.096 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, C-terminal domain CcmB PF03379.8 EKX73688.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 CcmB protein FAINT PF04385.10 EKX73691.1 - 1.5e-86 284.2 91.6 4.9e-07 29.5 0.8 23.0 23 0 0 23 23 23 20 Domain of unknown function, DUF529 TruB-C_2 PF09157.6 EKX73691.1 - 0.21 11.4 0.0 0.47 10.3 0.0 1.5 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal ABC_tran PF00005.22 EKX73692.1 - 5.2e-30 104.5 0.0 2.1e-16 60.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 EKX73692.1 - 1.1e-06 28.8 0.2 0.015 15.3 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EKX73692.1 - 0.00011 21.6 1.5 0.11 11.9 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.1 EKX73692.1 - 0.00019 21.0 0.1 0.061 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EKX73692.1 - 0.00021 20.7 0.0 0.082 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EKX73692.1 - 0.00025 19.9 0.5 0.0006 18.6 0.0 1.7 2 0 0 2 2 2 1 ArgK protein AAA_23 PF13476.1 EKX73692.1 - 0.00025 21.4 4.2 0.079 13.2 0.6 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EKX73692.1 - 0.00031 19.7 0.4 0.62 8.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 EKX73692.1 - 0.00043 21.1 0.0 0.24 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EKX73692.1 - 0.0018 17.5 0.8 0.098 11.8 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EKX73692.1 - 0.0018 18.5 0.1 0.89 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EKX73692.1 - 0.0025 17.2 0.2 0.42 10.0 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_21 PF13304.1 EKX73692.1 - 0.003 17.5 11.0 0.049 13.5 0.0 4.6 5 0 0 5 5 4 1 AAA domain MobB PF03205.9 EKX73692.1 - 0.0035 17.0 0.5 0.79 9.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EKX73692.1 - 0.0039 16.9 0.5 2 8.2 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Miro PF08477.8 EKX73692.1 - 0.0041 17.6 0.1 4.1 7.9 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EKX73692.1 - 0.0042 17.2 0.0 3.4 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EKX73692.1 - 0.0094 15.7 2.9 0.14 11.9 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function DUF87 NACHT PF05729.7 EKX73692.1 - 0.013 15.1 0.7 3.6 7.2 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 EKX73692.1 - 0.019 14.0 0.3 5.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin UPF0079 PF02367.12 EKX73692.1 - 0.021 14.4 0.6 0.52 9.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EKX73692.1 - 0.021 14.5 0.1 8.2 6.0 0.0 2.7 3 0 0 3 3 2 0 Archaeal ATPase SMC_N PF02463.14 EKX73692.1 - 0.025 13.8 1.1 0.2 10.8 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EKX73692.1 - 0.06 13.3 1.2 0.34 10.8 0.0 2.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase NB-ARC PF00931.17 EKX73692.1 - 0.063 12.1 0.2 0.66 8.7 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain SbcCD_C PF13558.1 EKX73692.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 EKX73692.1 - 0.12 12.2 1.5 16 5.2 0.1 2.9 3 0 0 3 3 3 0 Dynamin family AAA_33 PF13671.1 EKX73692.1 - 0.14 12.0 0.5 11 5.8 0.1 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EKX73692.1 - 0.16 11.4 1.4 10 5.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2791 PF10923.3 EKX73692.1 - 0.23 9.9 0.0 1.4 7.4 0.0 2.0 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) AAA_10 PF12846.2 EKX73692.1 - 0.25 10.7 1.1 5.9 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain DUF2275 PF10039.4 EKX73692.1 - 0.53 10.1 0.6 0.92 9.3 0.4 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) FAINT PF04385.10 EKX73693.1 - 8.2e-16 57.6 9.2 2.5e-05 24.0 0.2 4.2 3 2 2 5 5 5 3 Domain of unknown function, DUF529 adh_short PF00106.20 EKX73694.1 - 4.4e-19 69.0 0.0 6.9e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKX73694.1 - 7.4e-05 22.4 0.0 0.0021 17.7 0.0 2.3 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EKX73694.1 - 0.00017 21.4 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EKX73694.1 - 0.0023 17.9 0.0 0.025 14.6 0.0 2.1 1 1 1 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 EKX73694.1 - 0.0035 16.5 0.0 0.019 14.1 0.0 1.8 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) COX14 PF14880.1 EKX73695.1 - 0.057 13.0 0.2 0.081 12.5 0.1 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Dynamin_N PF00350.18 EKX73696.1 - 8.6e-13 48.4 0.0 3.4e-12 46.5 0.0 2.0 1 0 0 1 1 1 1 Dynamin family GDPD PF03009.12 EKX73697.1 - 1.4e-15 57.4 0.0 1.5e-13 50.8 0.0 2.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PAX PF00292.13 EKX73697.1 - 0.042 13.5 0.0 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 'Paired box' domain DUF433 PF04255.9 EKX73697.1 - 0.065 12.6 0.0 26 4.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF433) Adap_comp_sub PF00928.16 EKX73698.1 - 9.2e-47 159.3 0.1 1.2e-46 158.9 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Methyltransf_15 PF09445.5 EKX73699.1 - 1.7e-25 89.4 0.0 2.9e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RNA_GG_bind PF10258.4 EKX73699.1 - 4.2e-07 29.5 0.0 8.4e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 PHAX RNA-binding domain Methyltransf_26 PF13659.1 EKX73699.1 - 1.7e-05 24.8 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKX73699.1 - 0.045 14.3 0.0 0.13 12.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain GRAM PF02893.15 EKX73700.1 - 1.8e-07 30.5 2.1 9.5e-07 28.2 0.1 2.7 2 0 0 2 2 2 1 GRAM domain zf-primase PF09329.6 EKX73700.1 - 0.053 13.1 1.1 0.21 11.2 0.1 2.3 2 0 0 2 2 2 0 Primase zinc finger Angiomotin_C PF12240.3 EKX73700.1 - 0.062 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Angiomotin C terminal Ribosomal_S18 PF01084.15 EKX73701.1 - 1.3e-16 60.1 0.1 1.3e-16 60.1 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S18 Mt_ATP-synt_D PF05873.7 EKX73701.1 - 0.0069 16.0 1.2 0.02 14.5 0.8 1.7 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF327 PF03885.8 EKX73701.1 - 0.29 10.9 3.5 0.18 11.6 0.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF327) PDEase_I PF00233.14 EKX73702.1 - 3.1e-49 167.8 0.0 5.1e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase YolD PF08863.5 EKX73702.1 - 0.065 13.0 0.1 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 YolD-like protein DnaJ PF00226.26 EKX73703.1 - 7.4e-29 99.2 1.5 1e-28 98.7 1.0 1.2 1 0 0 1 1 1 1 DnaJ domain MCM PF00493.18 EKX73704.1 - 7.1e-76 255.1 0.0 1e-75 254.6 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 EKX73704.1 - 2e-09 36.9 0.1 2.3e-06 26.9 0.1 2.6 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EKX73704.1 - 4.5e-08 32.7 0.0 9.9e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKX73704.1 - 5.2e-08 32.7 0.0 1.1e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EKX73704.1 - 4.4e-07 30.1 0.0 8.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EKX73704.1 - 6.2e-06 25.7 0.0 0.0049 16.3 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain MMR_HSR1 PF01926.18 EKX73704.1 - 0.0011 18.8 0.1 0.05 13.5 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EKX73704.1 - 0.0019 18.1 0.1 0.0051 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EKX73704.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EKX73704.1 - 0.019 15.1 0.0 0.064 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF3497 PF12003.3 EKX73704.1 - 0.06 12.7 0.1 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3497) NACHT PF05729.7 EKX73704.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 EKX73704.1 - 0.098 12.0 0.1 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.7 EKX73704.1 - 0.1 11.6 0.0 0.44 9.5 0.0 2.0 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Gag_p10 PF02337.12 EKX73705.1 - 0.05 13.3 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral GAG p10 protein Amino_oxidase PF01593.19 EKX73706.1 - 3.9e-46 158.0 0.0 6.7e-35 121.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EKX73706.1 - 8e-12 45.0 0.1 1.9e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EKX73706.1 - 1.1e-07 31.1 0.1 1.7e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKX73706.1 - 3.3e-07 29.5 0.0 5.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EKX73706.1 - 1.8e-06 27.2 0.0 3.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EKX73706.1 - 4.1e-06 26.1 0.2 7.7e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EKX73706.1 - 1.2e-05 24.5 0.8 2.1e-05 23.7 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EKX73706.1 - 2.4e-05 24.3 0.0 4.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKX73706.1 - 0.00024 21.4 1.1 0.00063 20.0 0.0 2.3 3 0 0 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKX73706.1 - 0.0011 17.5 0.2 0.0025 16.3 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EKX73706.1 - 0.0011 19.0 0.0 0.0031 17.5 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EKX73706.1 - 0.0011 17.8 0.2 0.0019 17.1 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EKX73706.1 - 0.0022 16.9 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein zf-RING-like PF08746.6 EKX73706.1 - 0.007 16.3 4.1 0.019 14.9 2.8 1.8 1 0 0 1 1 1 1 RING-like domain Trp_halogenase PF04820.9 EKX73706.1 - 0.1 11.2 0.2 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MCM PF00493.18 EKX73707.1 - 2.3e-128 427.6 3.7 2.3e-128 427.6 0.3 2.0 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EKX73707.1 - 9.6e-08 32.5 1.0 9.6e-08 32.5 0.7 2.0 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EKX73707.1 - 3.8e-07 29.4 0.0 2.5e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EKX73707.1 - 0.0076 15.7 0.0 0.023 14.2 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 EKX73707.1 - 0.0088 15.7 0.0 0.024 14.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EKX73707.1 - 0.037 13.6 0.0 0.082 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ubiquitin PF00240.18 EKX73708.1 - 1.5e-71 235.7 5.2 3.4e-35 119.2 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 EKX73708.1 - 6.4e-42 141.0 4.6 2.9e-20 71.7 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EKX73708.1 - 9.9e-15 54.5 1.0 1.1e-05 25.6 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EKX73708.1 - 2e-10 40.5 0.0 0.00059 19.5 0.0 2.0 2 0 0 2 2 2 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EKX73708.1 - 1e-07 31.8 0.3 0.022 14.6 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EKX73708.1 - 2e-06 27.9 0.1 0.067 13.3 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EKX73708.1 - 5.6e-06 26.1 0.2 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 GLUT4 regulating protein TUG DUF2870 PF11069.3 EKX73708.1 - 5.2e-05 23.1 0.0 0.53 10.3 0.0 2.7 2 2 0 2 2 2 2 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EKX73708.1 - 0.0011 18.6 0.2 2 8.2 0.0 2.3 2 0 0 2 2 2 2 FlgD Ig-like domain USP7_C2 PF14533.1 EKX73708.1 - 0.0031 16.9 0.3 2 7.7 0.0 2.1 1 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal Plexin_cytopl PF08337.7 EKX73708.1 - 0.016 13.5 2.5 1.7 6.8 0.1 3.3 2 1 1 3 3 3 0 Plexin cytoplasmic RasGAP domain FERM_N PF09379.5 EKX73708.1 - 0.017 15.1 1.1 13 5.8 0.1 3.4 2 2 0 2 2 2 0 FERM N-terminal domain CTDII PF01556.13 EKX73708.1 - 0.017 14.9 3.5 0.83 9.5 0.2 2.3 1 1 1 2 2 2 0 DnaJ C terminal domain GABP-alpha PF11620.3 EKX73708.1 - 0.13 12.3 0.3 16 5.5 0.0 2.1 2 0 0 2 2 2 0 GA-binding protein alpha chain DUF2207 PF09972.4 EKX73708.1 - 0.17 10.4 2.1 6.2 5.2 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) E1-E2_ATPase PF00122.15 EKX73709.1 - 6.1e-62 208.6 5.8 6.1e-62 208.6 4.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EKX73709.1 - 5.4e-35 120.5 0.4 3e-34 118.1 0.0 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EKX73709.1 - 2.5e-30 106.4 0.0 4.9e-29 102.2 0.0 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EKX73709.1 - 6.3e-17 60.7 0.1 1.9e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EKX73709.1 - 8.6e-15 55.4 0.2 1.8e-13 51.0 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKX73709.1 - 7.2e-13 48.3 0.0 2.4e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EKX73709.1 - 0.00077 19.1 1.6 0.018 14.6 0.6 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EKX73709.1 - 0.022 14.9 0.0 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TAF1D PF15333.1 EKX73710.1 - 0.0069 16.2 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 TATA box-binding protein-associated factor 1D AKAP7_RIRII_bdg PF10470.4 EKX73710.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein M11L PF11099.3 EKX73710.1 - 0.052 13.2 0.2 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Apoptosis regulator M11L like GCFC PF07842.7 EKX73712.1 - 4.3e-14 52.5 0.9 1.9e-12 47.1 0.1 2.5 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EKX73712.1 - 5.3e-10 38.9 5.6 5.3e-10 38.9 3.9 1.9 2 0 0 2 2 2 1 G-patch domain HALZ PF02183.13 EKX73712.1 - 0.00054 19.6 0.1 0.0017 18.0 0.1 1.8 1 0 0 1 1 1 1 Homeobox associated leucine zipper TIP_N PF12457.3 EKX73712.1 - 0.086 12.9 7.0 14 5.8 4.9 2.6 1 1 0 1 1 1 0 Tuftelin interacting protein N terminal Reo_sigmaC PF04582.7 EKX73712.1 - 0.49 9.5 3.3 1.9 7.5 0.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein MscS_porin PF12795.2 EKX73712.1 - 1.4 8.1 5.9 1 8.6 0.9 2.5 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Ribosomal_S16 PF00886.14 EKX73713.1 - 1.9e-09 37.0 0.0 1.3e-08 34.4 0.0 2.3 3 0 0 3 3 3 1 Ribosomal protein S16 TPT PF03151.11 EKX73714.1 - 8.8e-20 70.8 5.3 8.8e-20 70.8 3.7 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EKX73714.1 - 5e-06 26.5 20.2 0.0012 18.8 2.3 3.1 3 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EKX73714.1 - 1.8e-05 24.8 14.5 0.012 15.7 1.6 3.3 3 0 0 3 3 3 2 Multidrug resistance efflux transporter UAA PF08449.6 EKX73714.1 - 0.0046 15.9 14.4 0.021 13.7 10.0 1.9 1 1 0 1 1 1 1 UAA transporter family Phage_antitermQ PF06530.7 EKX73715.1 - 0.028 13.9 2.5 6.7 6.2 0.0 3.5 2 1 1 3 3 3 0 Phage antitermination protein Q FliG_N PF14842.1 EKX73715.1 - 0.054 13.6 0.0 0.85 9.7 0.0 2.5 2 1 1 3 3 3 0 FliG N-terminal domain Adap_comp_sub PF00928.16 EKX73716.1 - 4.1e-80 268.6 0.6 5.1e-80 268.3 0.4 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EKX73716.1 - 4.6e-07 29.6 1.7 8e-07 28.8 1.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA PF00004.24 EKX73717.1 - 6.5e-41 139.6 0.0 1.3e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKX73717.1 - 7.6e-07 29.3 0.1 8.3e-05 22.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EKX73717.1 - 1.2e-05 25.1 0.0 3.8e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EKX73717.1 - 2.4e-05 24.3 0.0 6.7e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EKX73717.1 - 0.00018 22.3 0.1 0.00039 21.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EKX73717.1 - 0.00034 20.5 0.0 0.00074 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EKX73717.1 - 0.00041 20.0 0.1 0.00091 18.9 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EKX73717.1 - 0.0011 18.1 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EKX73717.1 - 0.0033 16.3 0.0 0.0056 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EKX73717.1 - 0.011 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EKX73717.1 - 0.016 15.1 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EKX73717.1 - 0.017 15.3 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EKX73717.1 - 0.03 14.2 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EKX73717.1 - 0.041 14.0 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 EKX73717.1 - 0.043 13.3 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EKX73717.1 - 0.049 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EKX73717.1 - 0.06 12.5 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EKX73717.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EKX73717.1 - 0.077 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 EKX73717.1 - 0.083 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 EKX73717.1 - 0.088 11.9 0.0 1.2 8.1 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.1 EKX73717.1 - 0.098 12.0 0.0 0.81 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EKX73717.1 - 0.13 11.9 0.0 9.3 5.8 0.0 2.4 1 1 0 2 2 2 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EKX73717.1 - 0.13 12.2 0.0 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain PC_rep PF01851.17 EKX73719.1 - 3.5e-17 61.5 19.2 0.0014 18.7 0.0 8.7 10 0 0 10 10 10 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EKX73719.1 - 5.8e-05 23.2 0.1 0.019 15.2 0.0 3.7 3 1 1 4 4 4 1 HEAT repeats eIF2A PF08662.6 EKX73721.1 - 6.7e-65 218.4 0.1 1.5e-63 214.0 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DnaJ PF00226.26 EKX73722.1 - 6.3e-25 86.7 3.4 1e-24 86.0 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EKX73722.1 - 1.6e-18 66.3 2.9 2.4e-17 62.6 0.0 3.3 3 1 1 4 4 4 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EKX73722.1 - 1.3e-14 54.0 19.7 2.4e-14 53.1 13.7 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EKX73722.1 - 0.029 14.0 10.1 0.25 11.0 0.3 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family A2L_zn_ribbon PF08792.5 EKX73722.1 - 3.2 7.3 16.9 12 5.5 0.3 4.4 4 0 0 4 4 4 0 A2L zinc ribbon domain Cytochrom_c3_2 PF14537.1 EKX73722.1 - 8.8 6.7 16.8 0.35 11.2 6.6 2.3 2 1 0 2 2 2 0 Cytochrome c3 HEAT_2 PF13646.1 EKX73723.1 - 3.2e-29 101.0 0.1 9.4e-13 48.2 0.0 3.5 1 1 3 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 EKX73723.1 - 5.5e-17 60.4 0.2 0.0017 18.6 0.0 7.1 7 0 0 7 7 7 3 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EKX73723.1 - 2.4e-09 37.3 0.0 0.0084 16.5 0.0 4.4 3 2 1 4 4 4 3 HEAT-like repeat HEAT PF02985.17 EKX73723.1 - 8.4e-09 34.7 1.1 0.0025 17.7 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.18 EKX73723.1 - 0.0007 19.3 1.1 0.35 10.7 0.0 4.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat RAP-1 PF03085.10 EKX73724.1 - 3.7e-84 282.0 25.6 4.1e-29 101.6 7.2 3.3 1 1 2 3 3 3 3 Rhoptry-associated protein 1 (RAP-1) DUF2533 PF10752.4 EKX73724.1 - 2.2e-06 27.8 0.1 1.1 9.5 0.0 3.9 3 0 0 3 3 3 3 Protein of unknown function (DUF2533) RAP-1 PF03085.10 EKX73725.1 - 2.6e-69 233.3 3.2 3.8e-42 144.3 0.5 2.3 1 1 1 2 2 2 2 Rhoptry-associated protein 1 (RAP-1) UPF0731 PF14982.1 EKX73725.1 - 0.016 15.1 0.4 5 7.1 0.1 2.3 2 0 0 2 2 2 0 UPF0731 family PP28 PF10252.4 EKX73726.1 - 2.8e-22 78.5 13.2 8.7e-22 76.9 9.2 1.8 1 0 0 1 1 1 1 Casein kinase substrate phosphoprotein PP28 DUF2407 PF10302.4 EKX73726.1 - 0.025 14.7 2.3 0.025 14.7 1.6 1.9 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain DUF399 PF04187.8 EKX73726.1 - 0.39 10.1 5.2 0.51 9.8 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF399 TRAP_alpha PF03896.11 EKX73726.1 - 0.9 8.4 4.5 1.2 8.0 3.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 EKX73726.1 - 3.9 5.3 16.9 4.1 5.3 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SNARE PF05739.14 EKX73727.1 - 0.00051 19.6 2.2 0.00051 19.6 1.5 2.2 3 0 0 3 3 3 1 SNARE domain ODV-E18 PF10717.4 EKX73727.1 - 0.022 14.1 2.4 0.022 14.1 1.7 1.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Use1 PF09753.4 EKX73727.1 - 0.026 13.9 6.8 0.059 12.7 4.7 1.7 1 1 0 1 1 1 0 Membrane fusion protein Use1 Hormone_1 PF00103.15 EKX73727.1 - 0.05 12.9 1.3 0.17 11.2 0.1 2.2 1 1 0 2 2 2 0 Somatotropin hormone family DUF1664 PF07889.7 EKX73727.1 - 0.19 11.5 4.1 3.3 7.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EKX73727.1 - 0.41 10.9 3.4 5.5 7.3 0.0 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_11_kDa PF06143.6 EKX73727.1 - 1.8 7.9 6.4 4.4 6.7 4.4 1.7 1 1 0 1 1 1 0 Baculovirus 11 kDa family Helicase_C PF00271.26 EKX73728.1 - 1.9e-12 46.8 0.1 3.9e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 EKX73728.1 - 7.7e-09 35.5 0.0 2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 EKX73728.1 - 4.6e-05 22.9 0.5 0.00034 20.1 0.1 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EKX73728.1 - 0.00037 19.5 0.0 0.00091 18.2 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EKX73728.1 - 0.00061 19.9 0.0 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EKX73728.1 - 0.0067 15.5 0.2 0.016 14.3 0.1 1.5 1 0 0 1 1 1 1 KaiC AAA_29 PF13555.1 EKX73728.1 - 0.018 14.5 0.0 0.055 13.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EKX73728.1 - 0.022 13.6 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EKX73728.1 - 0.055 12.6 0.1 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Apc1 PF12859.2 EKX73728.1 - 0.065 13.4 0.0 0.29 11.3 0.0 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Sigma54_activat PF00158.21 EKX73728.1 - 0.13 11.7 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain zf-RING_2 PF13639.1 EKX73729.1 - 1.9e-12 46.8 4.2 1.9e-12 46.8 2.9 2.2 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EKX73729.1 - 5.7e-08 32.7 2.2 5.7e-08 32.7 1.5 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EKX73729.1 - 1.7e-06 27.9 3.6 1.7e-06 27.9 2.5 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKX73729.1 - 1.7e-06 27.5 2.3 1.7e-06 27.5 1.6 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKX73729.1 - 5.8e-06 25.9 2.2 5.8e-06 25.9 1.5 2.2 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EKX73729.1 - 0.012 15.2 5.4 0.012 15.2 3.7 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MRAP PF15183.1 EKX73729.1 - 0.32 10.6 6.7 1.1 8.9 2.4 2.6 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family zf-Apc11 PF12861.2 EKX73729.1 - 0.37 10.6 8.3 0.4 10.5 3.4 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 EKX73729.1 - 0.43 10.3 3.5 1 9.1 2.4 1.7 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EKX73729.1 - 0.49 10.4 6.5 3.2 7.7 4.1 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EKX73729.1 - 0.82 9.5 8.1 3.2 7.7 2.7 2.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 EKX73729.1 - 4.1 6.9 11.6 30 4.1 4.7 3.0 2 1 0 2 2 2 0 P-11 zinc finger Ion_trans PF00520.26 EKX73730.1 - 0.00072 18.8 3.9 0.0012 18.1 2.7 1.4 1 0 0 1 1 1 1 Ion transport protein NAD4L PF06235.6 EKX73730.1 - 0.015 15.0 2.9 0.037 13.7 2.0 1.6 1 0 0 1 1 1 0 NADH dehydrogenase subunit 4L (NAD4L) EBP PF05241.7 EKX73730.1 - 0.073 12.0 0.3 0.11 11.4 0.2 1.3 1 1 0 1 1 1 0 Emopamil binding protein PTPA PF03095.10 EKX73731.1 - 5.3e-76 255.6 0.0 6.9e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein His_Phos_2 PF00328.17 EKX73732.1 - 1.8e-47 162.3 0.0 3e-46 158.3 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EKX73732.1 - 5.2e-06 26.0 0.0 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.17 EKX73732.1 - 0.00025 21.1 0.0 0.0019 18.3 0.0 2.3 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Asp PF00026.18 EKX73733.1 - 1.4e-50 172.3 1.7 2.2e-50 171.7 1.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EKX73733.1 - 8.2e-08 32.3 0.5 2.8e-07 30.6 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal VPS28 PF03997.7 EKX73734.1 - 5.1e-35 120.7 0.0 6.1e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Pigment_DH PF06324.6 EKX73734.1 - 0.025 13.8 0.0 0.063 12.5 0.0 1.7 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) FAST_1 PF06743.10 EKX73736.1 - 0.001 18.7 0.1 0.96 9.2 0.0 4.9 4 1 0 4 4 4 1 FAST kinase-like protein, subdomain 1 CBF PF03914.12 EKX73736.1 - 0.061 12.7 4.8 0.066 12.6 0.5 2.6 2 1 0 2 2 2 0 CBF/Mak21 family Fibrinogen_aC PF12160.3 EKX73736.1 - 0.13 11.7 0.4 0.29 10.6 0.3 1.6 1 0 0 1 1 1 0 Fibrinogen alpha C domain Adaptin_N PF01602.15 EKX73737.1 - 1.8e-50 171.7 19.5 1.8e-50 171.7 13.5 2.0 2 0 0 2 2 2 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EKX73737.1 - 1.4e-28 99.1 0.0 3.3e-15 55.9 0.0 2.9 1 1 1 2 2 2 2 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EKX73737.1 - 2.9e-13 49.6 0.5 1e-12 47.9 0.3 1.9 1 1 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EKX73737.1 - 2.2e-05 24.6 0.2 0.0032 17.7 0.0 4.0 4 0 0 4 4 4 1 HEAT repeats DUF2435 PF10363.4 EKX73737.1 - 0.00031 20.5 2.8 0.01 15.6 0.0 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) HEAT PF02985.17 EKX73737.1 - 0.0022 17.9 2.2 0.37 10.9 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat DUF975 PF06161.6 EKX73738.1 - 0.064 12.9 1.5 0.085 12.5 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF975) Ribosomal_L18e PF00828.14 EKX73739.1 - 1.7e-05 25.1 0.4 5.5e-05 23.5 0.2 2.0 1 1 0 1 1 1 1 Ribosomal protein L18e/L15 Diphthamide_syn PF01866.12 EKX73740.1 - 1.2e-29 103.5 0.4 1.3e-16 60.6 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein CPW_WPC PF09717.5 EKX73741.1 - 2.3e-29 101.7 28.6 1.5e-13 51.1 1.5 3.1 3 0 0 3 3 3 3 Plasmodium falciparum domain of unknown function (CPW_WPC) COX2 PF00116.15 EKX73742.1 - 5.9e-39 132.6 0.0 7.1e-39 132.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Ribosomal_L17 PF01196.14 EKX73743.1 - 6.6e-19 68.2 0.1 1.5e-18 67.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 MMR_HSR1 PF01926.18 EKX73744.1 - 6.4e-17 61.5 0.5 1e-14 54.4 0.0 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKX73744.1 - 1.9e-06 27.2 0.2 7.9e-06 25.2 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EKX73744.1 - 0.0023 17.1 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 EKX73744.1 - 0.021 14.5 0.5 0.16 11.6 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Pkinase PF00069.20 EKX73746.1 - 5e-69 232.3 0.6 8.9e-69 231.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX73746.1 - 1.4e-31 109.5 0.2 2.7e-31 108.5 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKX73746.1 - 2.7e-06 26.5 0.0 2.4e-05 23.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EKX73746.1 - 0.0016 17.5 0.3 0.0027 16.8 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ATP-grasp_2 PF08442.5 EKX73747.1 - 5.5e-60 202.2 0.1 7.8e-60 201.7 0.1 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EKX73747.1 - 6e-19 68.1 0.0 1.3e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EKX73747.1 - 0.00024 20.3 0.1 0.00063 19.0 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 EKX73747.1 - 0.00043 19.9 0.0 0.00075 19.1 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain SF-assemblin PF06705.6 EKX73748.1 - 5.3e-17 61.7 26.9 6.5e-17 61.5 18.7 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Terpene_synth_C PF03936.11 EKX73748.1 - 0.0076 15.5 2.1 0.097 11.8 0.2 2.5 1 1 1 3 3 3 1 Terpene synthase family, metal binding domain TraC_F_IV PF11130.3 EKX73748.1 - 0.045 13.1 2.0 2.4 7.5 0.5 2.2 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer Apolipoprotein PF01442.13 EKX73748.1 - 0.1 12.0 16.0 0.7 9.3 0.5 2.4 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Mating_N PF12731.2 EKX73748.1 - 0.11 12.3 5.0 0.35 10.7 0.2 3.0 2 1 1 3 3 3 0 Mating-type protein beta 1 DUF2746 PF10874.3 EKX73748.1 - 0.16 12.1 11.6 0.51 10.5 0.4 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF2746) V-ATPase_G PF03179.10 EKX73748.1 - 0.94 9.8 15.8 1.2 9.4 4.1 2.5 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF1848 PF08902.6 EKX73748.1 - 2.1 7.8 7.2 0.68 9.4 2.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1848) Baculo_PEP_C PF04513.7 EKX73748.1 - 2.4 7.9 21.8 8.7 6.1 7.4 3.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 EKX73748.1 - 3.4 8.1 6.5 3.8 7.9 1.7 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4303 PF14136.1 EKX73748.1 - 6.5 6.3 10.7 2.5 7.7 0.9 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4303) YjcZ PF13990.1 EKX73748.1 - 6.5 5.7 11.5 2.5 7.1 5.7 1.8 1 1 1 2 2 2 0 YjcZ-like protein Phasin PF05597.6 EKX73748.1 - 6.6 6.5 15.8 2 8.1 4.6 2.9 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF651 PF04895.7 EKX73748.1 - 6.9 6.3 12.0 5.9 6.5 1.0 3.4 1 1 3 4 4 4 0 Archaeal protein of unknown function (DUF651) Ribosomal_L14e PF01929.12 EKX73749.1 - 8.5e-24 83.7 2.5 1.1e-23 83.3 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EKX73749.1 - 0.015 14.9 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 KOW motif DUF773 PF05600.7 EKX73750.1 - 2.5e-19 69.4 16.9 5.6e-15 55.1 0.4 2.2 2 1 0 2 2 2 2 Protein of unknown function (DUF773) FlaC_arch PF05377.6 EKX73750.1 - 1.5 8.7 11.0 0.67 9.8 0.8 4.0 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) THOC7 PF05615.8 EKX73751.1 - 0.025 14.8 3.3 0.023 14.9 1.3 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 HSBP1 PF06825.7 EKX73751.1 - 0.068 12.7 0.2 15 5.2 0.0 2.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF4041 PF13250.1 EKX73751.1 - 0.068 12.7 1.4 4.2 6.9 0.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4041) SNARE PF05739.14 EKX73751.1 - 0.085 12.5 1.5 0.34 10.6 1.1 2.1 1 0 0 1 1 1 0 SNARE domain BLOC1_2 PF10046.4 EKX73751.1 - 0.09 12.9 10.7 9.6 6.4 3.3 3.3 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin_2 PF14523.1 EKX73751.1 - 0.22 11.5 12.1 0.36 10.8 2.8 3.2 1 1 1 2 2 2 0 Syntaxin-like protein DUF948 PF06103.6 EKX73751.1 - 0.28 11.0 3.4 1 9.2 0.9 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CheZ PF04344.8 EKX73751.1 - 0.37 10.4 4.4 0.48 10.0 1.9 1.8 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ Syntaxin PF00804.20 EKX73751.1 - 0.85 9.8 12.2 0.25 11.5 0.3 2.7 1 1 1 2 2 2 0 Syntaxin DUF4460 PF14687.1 EKX73751.1 - 0.86 9.3 5.3 0.27 10.9 0.3 2.6 2 1 1 4 4 4 0 Domain of unknown function (DUF4460) Fib_alpha PF08702.5 EKX73751.1 - 0.87 9.6 10.7 0.92 9.6 3.9 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Nup54 PF13874.1 EKX73751.1 - 3 7.5 7.6 8.5 6.0 0.1 3.6 2 1 2 4 4 4 0 Nucleoporin complex subunit 54 Seryl_tRNA_N PF02403.17 EKX73751.1 - 3.9 7.5 9.5 2.1 8.4 2.4 2.9 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.6 EKX73751.1 - 8.9 5.7 9.7 5.4 6.4 3.0 2.8 2 2 1 3 3 3 0 Phage minor structural protein GP20 Nop10p PF04135.7 EKX73752.1 - 4.8e-20 71.0 0.7 5.3e-20 70.8 0.5 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Rtf2 PF04641.7 EKX73753.1 - 8.3e-47 159.5 0.1 1e-46 159.2 0.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EKX73753.1 - 9.5e-05 22.0 2.7 0.00025 20.6 1.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EKX73753.1 - 0.056 13.2 1.0 0.095 12.5 0.7 1.4 1 0 0 1 1 1 0 Ring finger domain DUF2072 PF09845.4 EKX73753.1 - 0.06 13.2 0.1 0.099 12.5 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) TF_Zn_Ribbon PF08271.7 EKX73753.1 - 0.075 12.3 2.9 0.25 10.7 1.6 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding zf-Nse PF11789.3 EKX73753.1 - 0.6 9.6 6.6 0.51 9.8 0.4 2.3 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RAP PF08373.5 EKX73754.1 - 0.00096 18.8 0.1 0.0024 17.6 0.1 1.7 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.10 EKX73754.1 - 0.058 13.1 0.2 1.7 8.4 0.0 3.1 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Rrp15p PF07890.7 EKX73756.1 - 0.03 14.3 4.9 0.057 13.4 3.4 1.6 1 1 0 1 1 1 0 Rrp15p DUF3452 PF11934.3 EKX73756.1 - 0.062 12.6 1.2 0.067 12.5 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) BDV_P10 PF06515.6 EKX73756.1 - 0.11 12.2 0.2 0.13 12.1 0.2 1.2 1 0 0 1 1 1 0 Borna disease virus P10 protein FAM217 PF15344.1 EKX73756.1 - 3.6 7.0 7.6 1.2 8.6 3.0 1.4 1 1 0 1 1 1 0 FAM217 family Abhydrolase_6 PF12697.2 EKX73757.1 - 6.2e-13 49.1 0.0 1.1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX73757.1 - 4.9e-11 42.5 0.0 1.4e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX73757.1 - 1.4e-08 34.4 0.2 3.1e-06 26.9 0.1 2.4 2 0 0 2 2 2 2 Putative lysophospholipase Abhydrolase_2 PF02230.11 EKX73757.1 - 0.0021 17.5 0.0 0.16 11.3 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EKX73757.1 - 0.0041 16.3 0.0 0.012 14.8 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EKX73757.1 - 0.047 13.2 0.0 0.12 11.8 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EKX73757.1 - 0.057 12.9 0.5 14 5.1 0.0 2.9 3 0 0 3 3 3 0 alpha/beta hydrolase fold zf-HC5HC2H_2 PF13832.1 EKX73758.1 - 2.9e-16 59.4 37.7 1.3e-14 54.1 3.7 4.5 3 2 1 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EKX73758.1 - 1.1e-09 38.3 15.5 8.7e-07 29.0 2.1 5.3 4 1 1 5 5 5 2 PHD-like zinc-binding domain Sybindin PF04099.7 EKX73759.1 - 6.2e-18 64.8 0.4 7.7e-18 64.5 0.3 1.3 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EKX73759.1 - 1e-06 28.6 0.0 1.7e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region MutS_V PF00488.16 EKX73760.1 - 1.3e-16 60.7 0.2 2.8e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.15 EKX73760.1 - 1.3e-08 34.8 0.0 3.3e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 MutS domain I AAA_14 PF13173.1 EKX73760.1 - 0.0045 16.8 0.5 0.036 13.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain GIY-YIG PF01541.19 EKX73760.1 - 0.22 11.8 9.4 0.073 13.4 2.8 2.8 2 1 0 2 2 2 0 GIY-YIG catalytic domain Ribonuc_red_sm PF00268.16 EKX73761.1 - 2.5e-106 354.8 0.4 3e-106 354.5 0.3 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain GTP_EFTU PF00009.22 EKX73762.1 - 1.8e-54 184.0 0.0 2.8e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EKX73762.1 - 1.1e-34 118.5 1.6 1e-33 115.3 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EKX73762.1 - 2.1e-15 56.5 0.2 6.3e-15 55.0 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EKX73762.1 - 8.4e-05 22.5 0.1 0.00037 20.4 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EKX73762.1 - 0.0023 17.5 0.1 0.0096 15.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.13 EKX73762.1 - 0.056 13.2 0.7 0.1 12.4 0.2 1.7 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.22 EKX73763.1 - 1.8e-54 184.0 0.0 2.8e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EKX73763.1 - 1.1e-34 118.5 1.6 1e-33 115.3 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EKX73763.1 - 2.1e-15 56.5 0.2 6.3e-15 55.0 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EKX73763.1 - 8.4e-05 22.5 0.1 0.00037 20.4 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EKX73763.1 - 0.0023 17.5 0.1 0.0096 15.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.13 EKX73763.1 - 0.056 13.2 0.7 0.1 12.4 0.2 1.7 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain tRNA-synt_1c PF00749.16 EKX73764.1 - 1.2e-75 254.0 0.5 4.7e-74 248.8 0.3 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Plasmid_parti PF01672.11 EKX73764.1 - 0.82 10.1 6.2 0.11 12.9 0.4 2.5 3 0 0 3 3 3 0 Putative plasmid partition protein Pkinase PF00069.20 EKX73765.1 - 6e-76 255.0 0.0 6.7e-76 254.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX73765.1 - 3e-33 115.0 0.0 3.7e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKX73765.1 - 0.00012 21.1 0.0 0.00019 20.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKX73765.1 - 0.0055 16.4 0.2 0.015 15.0 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EKX73765.1 - 0.034 13.2 0.0 0.097 11.7 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EKX73765.1 - 0.038 13.3 0.0 0.18 11.1 0.0 1.9 1 1 1 2 2 2 0 RIO1 family Cmc1 PF08583.5 EKX73766.1 - 0.003 17.3 1.9 0.0045 16.7 1.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like dTMP_synthase PF02593.9 EKX73766.1 - 0.004 16.5 0.1 0.0053 16.1 0.1 1.1 1 0 0 1 1 1 1 Thymidylate synthase Pet191_N PF10203.4 EKX73766.1 - 0.21 11.6 1.7 0.36 10.9 1.2 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DnaJ PF00226.26 EKX73767.1 - 1.6e-22 79.0 3.4 3.1e-22 78.0 2.3 1.5 1 0 0 1 1 1 1 DnaJ domain RCC1 PF00415.13 EKX73768.1 - 1.1e-37 127.9 9.2 5.1e-14 52.2 0.3 7.3 6 2 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EKX73768.1 - 2.2e-23 81.2 13.3 9.9e-09 34.5 0.0 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.20 EKX73769.1 - 2e-16 59.9 0.2 2.9e-09 36.4 0.1 3.9 2 2 0 2 2 2 2 Protein kinase domain UQ_con PF00179.21 EKX73770.1 - 1.6e-47 160.4 0.0 2.5e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.26 EKX73770.1 - 7.8e-06 25.5 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.1 EKX73770.1 - 3.4e-05 23.6 0.0 4.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_4 PF14555.1 EKX73770.1 - 0.00099 18.6 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain RWD PF05773.17 EKX73770.1 - 0.0032 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EKX73770.1 - 0.058 13.0 0.1 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Tim17 PF02466.14 EKX73771.1 - 1.1e-21 77.2 5.2 1.3e-21 76.9 3.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UEV PF05743.8 EKX73772.1 - 2e-24 85.5 0.3 2e-24 85.5 0.2 2.2 3 0 0 3 3 3 1 UEV domain Vps23_core PF09454.5 EKX73772.1 - 2.7e-05 23.6 0.2 6.1e-05 22.5 0.2 1.7 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 EKX73772.1 - 7.6e-05 22.1 0.6 0.00019 20.8 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4162 PF13732.1 EKX73772.1 - 0.09 13.3 1.8 0.22 12.0 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) DUF1664 PF07889.7 EKX73772.1 - 0.14 11.9 2.9 0.52 10.1 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Glutaredoxin PF00462.19 EKX73773.1 - 3.7e-16 58.8 0.1 7.9e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Cauli_DNA-bind PF03310.8 EKX73773.1 - 0.46 10.3 4.1 0.37 10.6 1.5 1.8 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein Cys_rich_VLP PF14194.1 EKX73773.1 - 1.3 8.8 5.4 7.3 6.4 0.0 2.8 2 1 0 2 2 2 0 Cysteine-rich VLP Spc7 PF08317.6 EKX73774.1 - 0.0004 19.1 36.4 0.0004 19.1 25.2 4.0 2 1 2 4 4 4 2 Spc7 kinetochore protein DUF3552 PF12072.3 EKX73774.1 - 0.0037 16.4 22.1 0.0037 16.4 15.3 5.8 2 1 4 6 6 6 4 Domain of unknown function (DUF3552) Flagellin_C PF00700.16 EKX73774.1 - 0.016 15.3 24.3 0.77 9.9 2.6 5.0 1 1 2 4 4 4 0 Bacterial flagellin C-terminal helical region Reo_sigmaC PF04582.7 EKX73774.1 - 0.82 8.7 23.9 1 8.4 3.9 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EKX73774.1 - 1.7 8.9 43.0 0.94 9.7 2.5 4.8 1 1 4 5 5 5 0 Nucleopolyhedrovirus P10 protein Sas10 PF09368.5 EKX73776.1 - 8.2e-21 73.9 7.6 8.2e-21 73.9 5.3 3.1 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EKX73776.1 - 2.3e-15 56.5 4.7 2.4e-15 56.4 1.2 2.6 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Filamin PF00630.14 EKX73777.1 - 6.2e-11 42.7 0.0 7.2e-10 39.3 0.0 2.7 2 0 0 2 2 2 1 Filamin/ABP280 repeat Perilipin PF03036.11 EKX73780.1 - 0.077 11.8 0.9 0.11 11.3 0.1 1.6 2 0 0 2 2 2 0 Perilipin family Ank_2 PF12796.2 EKX73782.1 - 5.5e-21 74.7 0.1 8.6e-21 74.0 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EKX73782.1 - 7.6e-21 72.8 0.7 3.2e-11 42.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EKX73782.1 - 3.7e-17 61.9 0.6 2.2e-11 43.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKX73782.1 - 2e-15 56.7 0.0 4.1e-08 33.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ACBP PF00887.14 EKX73782.1 - 1.4e-14 53.5 0.0 2.9e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_3 PF13606.1 EKX73782.1 - 1.4e-14 52.6 0.4 1.6e-06 27.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat SET PF00856.23 EKX73783.1 - 1.1e-08 35.5 0.0 3.1e-07 30.8 0.0 2.4 1 1 0 1 1 1 1 SET domain TPR_8 PF13181.1 EKX73783.1 - 2 8.4 7.1 12 5.9 1.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Nop PF01798.13 EKX73784.1 - 3.5e-54 182.1 0.1 5.9e-54 181.4 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EKX73784.1 - 1.7e-22 78.9 0.0 5.7e-21 74.0 0.0 2.3 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EKX73784.1 - 2.1e-19 69.4 0.1 2.1e-19 69.4 0.0 2.7 2 0 0 2 2 2 1 NOP5NT (NUC127) domain MOZ_SAS PF01853.13 EKX73786.1 - 2.3e-70 235.6 0.6 3.5e-70 235.1 0.4 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EKX73786.1 - 1.1e-11 44.2 0.3 2.5e-11 43.0 0.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-C2H2 PF00096.21 EKX73786.1 - 0.11 12.8 2.1 0.45 10.9 1.5 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKX73786.1 - 8.9 6.9 7.8 1.3 9.5 2.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M16_C PF05193.16 EKX73787.1 - 6.7e-15 55.2 0.0 8.5e-07 28.8 0.0 3.9 3 1 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EKX73787.1 - 4.1e-09 36.3 0.0 1.8e-07 31.0 0.0 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) HSP90 PF00183.13 EKX73788.1 - 7.1e-77 259.0 9.0 1.7e-76 257.7 4.9 1.9 1 1 1 2 2 2 1 Hsp90 protein HATPase_c_3 PF13589.1 EKX73788.1 - 1.4e-13 50.6 0.2 3.2e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EKX73788.1 - 3.9e-07 29.7 0.0 1.1e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hen1_L PF12623.2 EKX73788.1 - 0.0082 14.9 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 RNA repair, ligase-Pnkp-associating, region of Hen1 Clat_adaptor_s PF01217.15 EKX73789.1 - 5e-49 165.6 4.3 5.7e-49 165.4 3.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DNA_mis_repair PF01119.14 EKX73792.1 - 2.7e-18 65.5 0.3 6e-18 64.4 0.2 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EKX73792.1 - 5.5e-14 51.9 0.0 1.3e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EKX73792.1 - 4.4e-09 36.0 0.0 9.5e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ras PF00071.17 EKX73793.1 - 3.5e-48 163.0 0.0 4.2e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKX73793.1 - 5.6e-15 55.8 0.0 1.4e-14 54.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKX73793.1 - 2.8e-12 46.2 0.0 3.7e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKX73793.1 - 0.0016 17.6 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 EKX73793.1 - 0.0017 18.5 0.0 0.0072 16.4 0.0 1.9 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.15 EKX73793.1 - 0.004 15.8 0.1 0.35 9.4 0.1 2.8 2 1 1 3 3 3 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EKX73793.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EKX73793.1 - 0.02 15.0 0.2 0.21 11.7 0.1 2.2 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EKX73793.1 - 0.039 13.9 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EKX73793.1 - 0.061 13.6 0.1 0.89 9.8 0.0 2.3 2 1 0 2 2 2 0 ABC transporter NACHT PF05729.7 EKX73793.1 - 0.085 12.5 0.3 0.29 10.7 0.1 1.8 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 EKX73793.1 - 0.1 11.4 0.1 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Septin PF00735.13 EKX73793.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.4 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 EKX73793.1 - 0.12 11.9 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EKX73793.1 - 0.13 12.0 0.1 0.33 10.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EKX73793.1 - 0.14 11.7 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EKX73793.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 efThoc1 PF11957.3 EKX73794.1 - 0.00078 18.0 5.3 0.02 13.4 3.7 2.8 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor tRNA-synt_1b PF00579.20 EKX73796.1 - 1.4e-36 126.1 0.6 5.1e-36 124.2 0.4 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF3273 PF11677.3 EKX73797.1 - 1.8e-110 368.3 17.7 2.3e-110 368.0 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Clat_adaptor_s PF01217.15 EKX73799.1 - 5e-43 146.2 5.1 5.5e-43 146.0 3.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3232 PF11554.3 EKX73799.1 - 0.083 12.8 0.2 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) FAINT PF04385.10 EKX73800.1 - 9.1e-17 60.6 13.3 6.1e-05 22.7 1.4 4.5 4 0 0 4 4 4 4 Domain of unknown function, DUF529 PAS_10 PF13596.1 EKX73800.1 - 8e-05 22.8 0.1 0.19 11.9 0.0 3.1 3 0 0 3 3 3 2 PAS domain FAINT PF04385.10 EKX73801.1 - 2.7e-11 43.1 1.9 0.00089 19.0 0.6 3.3 3 0 0 3 3 3 3 Domain of unknown function, DUF529 DEAD PF00270.24 EKX73803.1 - 3.4e-43 147.0 0.6 2.4e-42 144.3 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKX73803.1 - 7.2e-29 99.4 0.3 9.8e-28 95.8 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EKX73803.1 - 4.3e-05 23.1 0.1 0.00046 19.8 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 EKX73803.1 - 0.0004 20.2 0.7 0.0026 17.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EKX73803.1 - 0.0015 18.1 0.0 0.0048 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 EKX73803.1 - 0.023 13.7 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PhoH PF02562.11 EKX73803.1 - 0.043 13.0 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein TilS_C PF11734.3 EKX73804.1 - 0.055 12.6 0.0 0.55 9.4 0.0 2.2 2 0 0 2 2 2 0 TilS substrate C-terminal domain ABC_tran PF00005.22 EKX73807.1 - 4.7e-29 101.4 0.0 7.5e-15 55.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 EKX73807.1 - 1.6e-05 25.0 0.1 0.024 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EKX73807.1 - 2.8e-05 23.5 1.4 0.19 11.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EKX73807.1 - 0.00013 22.0 10.0 0.067 13.1 0.1 4.2 4 1 0 4 4 2 2 AAA domain AAA_17 PF13207.1 EKX73807.1 - 0.00019 22.2 0.0 0.1 13.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKX73807.1 - 0.00022 21.5 0.1 0.73 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EKX73807.1 - 0.00023 20.0 0.5 0.0021 16.8 0.0 2.0 2 0 0 2 2 2 1 ArgK protein AAA_25 PF13481.1 EKX73807.1 - 0.00039 19.8 0.0 0.063 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EKX73807.1 - 0.00091 19.0 0.4 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 EKX73807.1 - 0.0011 18.7 2.1 0.11 12.2 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 T2SE PF00437.15 EKX73807.1 - 0.0019 17.1 1.3 0.41 9.4 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_30 PF13604.1 EKX73807.1 - 0.002 17.7 0.1 0.25 10.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EKX73807.1 - 0.002 18.4 3.6 0.52 10.6 0.3 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EKX73807.1 - 0.0024 17.0 0.2 0.66 9.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EKX73807.1 - 0.0052 16.2 0.3 0.59 9.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 EKX73807.1 - 0.0076 16.7 0.1 3.7 8.0 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein Zeta_toxin PF06414.7 EKX73807.1 - 0.008 15.2 0.2 3.5 6.6 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin SMC_N PF02463.14 EKX73807.1 - 0.01 15.0 0.8 0.1 11.8 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EKX73807.1 - 0.013 15.6 0.0 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EKX73807.1 - 0.014 15.0 0.4 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Fer4_NifH PF00142.13 EKX73807.1 - 0.016 14.3 0.1 4.2 6.4 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MMR_HSR1 PF01926.18 EKX73807.1 - 0.019 14.8 0.2 0.42 10.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 EKX73807.1 - 0.028 14.0 0.4 7.8 6.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 EKX73807.1 - 0.041 13.7 0.1 4.8 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EKX73807.1 - 0.086 12.3 0.1 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 EKX73807.1 - 0.11 12.1 0.6 3 7.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EKX73807.1 - 0.14 11.5 0.5 14 4.9 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 EKX73807.1 - 0.14 11.0 0.1 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 EKX73807.1 - 0.18 11.5 0.7 24 4.7 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain NB-ARC PF00931.17 EKX73807.1 - 0.18 10.5 0.2 0.76 8.5 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain DUF605 PF04652.11 EKX73808.1 - 0.23 10.8 10.8 0.33 10.2 7.5 1.2 1 0 0 1 1 1 0 Vta1 like F-box PF00646.28 EKX73809.1 - 0.11 12.2 2.0 0.15 11.7 0.3 2.1 2 0 0 2 2 2 0 F-box domain CAF1C_H4-bd PF12265.3 EKX73812.1 - 8.2e-20 70.4 0.0 1.7e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 EKX73812.1 - 1.8e-19 68.8 12.8 4.1e-06 26.4 0.3 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EKX73812.1 - 0.0038 16.9 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A FAINT PF04385.10 EKX73814.1 - 4.7e-05 23.1 0.0 7.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Myosin_head PF00063.16 EKX73815.1 - 4.3e-189 629.9 4.3 7.3e-189 629.1 3.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) WD40 PF00400.27 EKX73815.1 - 4.4e-16 58.0 4.3 5.3e-05 22.9 0.1 7.4 6 1 0 6 6 6 3 WD domain, G-beta repeat IQ PF00612.22 EKX73815.1 - 4.7e-11 41.3 17.0 0.00092 18.6 0.0 4.8 4 0 0 4 4 4 3 IQ calmodulin-binding motif AAA_22 PF13401.1 EKX73815.1 - 5.1e-07 29.8 3.9 0.14 12.3 0.0 4.2 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.1 EKX73815.1 - 6.5e-05 22.9 0.0 0.39 10.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.17 EKX73815.1 - 0.0008 19.5 0.1 3.2 7.9 0.0 3.5 2 0 0 2 2 2 2 RNA helicase Reo_sigmaC PF04582.7 EKX73815.1 - 0.0062 15.7 0.7 0.0062 15.7 0.5 1.8 2 0 0 2 2 2 1 Reovirus sigma C capsid protein AAA_17 PF13207.1 EKX73815.1 - 0.0075 17.0 0.0 3.1 8.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EKX73815.1 - 0.018 14.1 4.8 1.2 8.1 0.1 3.6 4 0 0 4 4 4 0 Zeta toxin ABC_tran PF00005.22 EKX73815.1 - 0.021 15.1 0.9 4.7 7.5 0.0 3.1 3 0 0 3 3 2 0 ABC transporter AAA_18 PF13238.1 EKX73815.1 - 0.034 14.4 0.1 5.1 7.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EKX73815.1 - 0.047 13.2 0.3 2.2 7.8 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EKX73815.1 - 0.05 13.3 0.3 1.4 8.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EKX73815.1 - 0.4 10.0 3.4 6.7 6.0 0.0 3.5 4 0 0 4 4 4 0 AAA-like domain IncA PF04156.9 EKX73815.1 - 0.87 9.1 12.4 1.1 8.8 7.9 1.6 1 1 0 1 1 1 0 IncA protein Myosin_N PF02736.14 EKX73816.1 - 0.029 14.0 1.3 0.045 13.4 0.9 1.4 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Ogr_Delta PF04606.7 EKX73817.1 - 0.05 13.2 0.4 0.1 12.2 0.3 1.5 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.5 EKX73817.1 - 0.14 12.1 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DUF1610 PF07754.6 EKX73817.1 - 5.8 7.1 6.6 1 9.5 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) PI-PLC-X PF00388.14 EKX73818.1 - 2.1e-39 134.2 0.0 4.5e-39 133.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EKX73818.1 - 1.2e-24 86.5 0.0 2.8e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EKX73818.1 - 2.3e-08 33.7 1.0 1.2e-07 31.4 0.7 2.2 1 1 0 1 1 1 1 C2 domain Mcp5_PH PF12814.2 EKX73818.1 - 0.0001 22.2 0.2 0.00021 21.1 0.1 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology FAINT PF04385.10 EKX73819.1 - 6.1e-06 25.9 3.1 0.00013 21.7 0.2 2.9 3 0 0 3 3 3 2 Domain of unknown function, DUF529 Pico_P2A PF00947.14 EKX73821.1 - 0.045 13.5 0.4 0.14 11.9 0.3 1.8 1 0 0 1 1 1 0 Picornavirus core protein 2A HAUS-augmin3 PF14932.1 EKX73822.1 - 0.084 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Lar_restr_allev PF14354.1 EKX73824.1 - 0.16 12.3 2.9 0.1 12.8 0.2 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar Utp14 PF04615.8 EKX73826.1 - 1.3e-47 162.4 49.8 1.3e-47 162.4 34.5 3.6 2 1 0 2 2 2 1 Utp14 protein DUF3958 PF13125.1 EKX73829.1 - 0.037 13.9 0.4 0.12 12.2 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) SUKH_6 PF14568.1 EKX73829.1 - 2.3 8.7 9.4 0.46 10.9 0.4 3.1 4 0 0 4 4 4 0 SMI1-KNR4 cell-wall FAINT PF04385.10 EKX73830.1 - 3.3e-07 30.0 7.2 0.00041 20.1 1.5 2.7 2 1 0 2 2 2 2 Domain of unknown function, DUF529 Pribosyltran PF00156.22 EKX73831.1 - 1.1e-19 70.4 0.0 1.4e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EKX73831.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Aconitase_2_N PF06434.8 EKX73831.1 - 0.075 12.4 0.1 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Aconitate hydratase 2 N-terminus BT1 PF03092.11 EKX73832.1 - 3.9e-43 147.7 6.7 4.4e-43 147.5 4.6 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 EKX73832.1 - 0.0018 17.0 0.0 0.0024 16.6 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EKX73832.1 - 0.049 12.0 4.6 0.042 12.2 1.2 1.9 2 0 0 2 2 2 0 MFS/sugar transport protein FAINT PF04385.10 EKX73833.1 - 3.6e-42 142.0 22.7 1.5e-07 31.1 0.2 8.6 8 0 0 8 8 8 8 Domain of unknown function, DUF529 BT1 PF03092.11 EKX73834.1 - 3.1e-13 49.2 5.0 4.3e-13 48.7 3.5 1.2 1 0 0 1 1 1 1 BT1 family MFS_2 PF13347.1 EKX73834.1 - 0.12 10.7 10.0 2.2 6.6 4.9 2.1 1 1 1 2 2 2 0 MFS/sugar transport protein FAINT PF04385.10 EKX73836.1 - 7.1e-86 282.1 88.4 6.1e-06 26.0 0.0 23.1 22 0 0 22 22 22 21 Domain of unknown function, DUF529 TruB-C_2 PF09157.6 EKX73836.1 - 0.78 9.6 0.0 1.8 8.4 0.0 1.5 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal Myb_DNA-binding PF00249.26 EKX73837.1 - 4e-09 36.3 0.5 1.6e-08 34.4 0.0 2.3 2 1 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 EKX73837.1 - 5.1e-06 25.9 7.0 1e-05 24.9 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Baculo_IE-1 PF05290.6 EKX73837.1 - 0.0058 16.3 3.7 0.016 14.9 2.5 1.7 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) AP2 PF00847.15 EKX73838.1 - 0.0047 17.0 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 AP2 domain Pkinase PF00069.20 EKX73839.1 - 4.1e-57 193.2 0.0 5.1e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX73839.1 - 3.8e-24 85.1 0.2 8.9e-24 83.9 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKX73839.1 - 0.00053 19.0 0.0 0.00097 18.2 0.0 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3800 PF12686.2 EKX73839.1 - 0.0065 16.1 0.3 0.011 15.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3800) RIO1 PF01163.17 EKX73839.1 - 0.015 14.6 0.3 0.024 13.9 0.2 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EKX73839.1 - 0.093 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SPRY PF00622.23 EKX73842.1 - 3.9e-15 56.0 1.0 7e-15 55.2 0.2 1.8 2 0 0 2 2 2 1 SPRY domain LisH PF08513.6 EKX73842.1 - 0.0003 20.4 0.0 0.00059 19.5 0.0 1.5 1 0 0 1 1 1 1 LisH CLTH PF10607.4 EKX73842.1 - 0.0012 18.5 0.1 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DUF2719 PF10891.3 EKX73846.1 - 0.0095 15.6 0.0 0.0095 15.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2719) Ank_2 PF12796.2 EKX73847.1 - 9.8e-29 99.5 0.8 2.2e-16 59.9 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EKX73847.1 - 1.2e-22 78.4 0.2 5.1e-07 29.1 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EKX73847.1 - 7.3e-21 74.1 4.3 4.9e-08 33.2 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKX73847.1 - 2.4e-20 70.5 1.2 1.8e-05 24.5 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Bromodomain PF00439.20 EKX73847.1 - 4.5e-17 61.7 0.1 1.2e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Ank_5 PF13857.1 EKX73847.1 - 1.6e-15 56.7 4.3 8.4e-07 29.0 0.1 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) SSURE PF11966.3 EKX73847.1 - 0.015 14.8 0.1 0.65 9.6 0.0 2.8 1 1 2 3 3 3 0 Fibronectin-binding repeat Toxin_30 PF08117.6 EKX73847.1 - 0.53 10.3 5.9 34 4.5 0.0 3.5 3 1 0 3 3 3 0 Ptu family PMM PF03332.8 EKX73848.1 - 2.2e-75 253.0 0.4 3e-48 164.2 0.1 2.2 2 0 0 2 2 2 2 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EKX73848.1 - 1.2e-08 34.8 0.0 2.7e-06 27.1 0.0 2.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX73848.1 - 0.0011 18.3 0.0 0.5 9.6 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Tet_JBP PF12851.2 EKX73848.1 - 0.03 13.6 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily DUF1319 PF07028.6 EKX73849.1 - 0.07 13.3 3.5 0.47 10.6 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) LRR_4 PF12799.2 EKX73849.1 - 1 9.0 5.3 0.8 9.3 0.6 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Yip1 PF04893.12 EKX73852.1 - 0.00067 19.1 17.2 0.0012 18.4 11.8 1.6 1 1 0 1 1 1 1 Yip1 domain Gcd10p PF04189.8 EKX73853.1 - 4.3e-54 183.6 0.7 8.3e-54 182.7 0.5 1.4 1 0 0 1 1 1 1 Gcd10p family FAINT PF04385.10 EKX73853.1 - 2.2e-11 43.4 0.2 0.025 14.4 0.0 4.0 3 0 0 3 3 3 3 Domain of unknown function, DUF529 MTS PF05175.9 EKX73853.1 - 0.00089 18.6 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ribosomal_L11_N PF03946.9 EKX73854.1 - 3.2e-20 71.3 0.1 1.3e-19 69.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EKX73854.1 - 5.3e-19 68.1 0.0 8.2e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Actin PF00022.14 EKX73855.1 - 2.7e-86 289.4 0.0 3.1e-86 289.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EKX73855.1 - 0.2 10.2 0.0 1.9 7.0 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Es2 PF09751.4 EKX73858.1 - 3.9e-50 171.5 5.1 3.6e-38 132.0 0.4 3.1 2 1 1 3 3 3 2 Nuclear protein Es2 FMN_bind_2 PF04299.7 EKX73860.1 - 0.094 12.1 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Putative FMN-binding domain DUF1451 PF07295.6 EKX73860.1 - 0.11 12.2 0.9 0.18 11.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Nol1_Nop2_Fmu PF01189.12 EKX73861.1 - 9.6e-20 71.1 0.0 5.3e-16 58.8 0.0 2.1 2 0 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EKX73861.1 - 5e-05 22.9 0.0 0.0034 16.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKX73861.1 - 0.0015 18.5 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKX73861.1 - 0.0036 17.8 0.0 0.01 16.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EKX73861.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase FAINT PF04385.10 EKX73864.1 - 2.9e-11 43.0 0.1 5.2e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 EMA PF02488.10 EKX73864.1 - 0.019 14.4 0.5 0.036 13.5 0.4 1.4 1 1 0 1 1 1 0 Merozoite Antigen Vps35 PF03635.12 EKX73866.1 - 1.4e-183 612.0 4.5 3.6e-181 604.1 2.0 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 FAINT PF04385.10 EKX73868.1 - 8.5e-28 96.0 7.1 4.9e-07 29.5 0.0 4.8 4 1 1 5 5 5 4 Domain of unknown function, DUF529 EMA PF02488.10 EKX73868.1 - 1.7e-10 40.8 11.7 8.5e-06 25.4 1.3 3.2 2 1 1 3 3 3 3 Merozoite Antigen CwfJ_C_1 PF04677.10 EKX73868.1 - 0.068 12.8 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 zf-CCCH PF00642.19 EKX73869.1 - 8.5e-09 34.8 2.5 8.5e-09 34.8 1.7 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 EKX73869.1 - 0.00019 21.0 11.3 0.00062 19.4 7.9 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKX73869.1 - 0.00054 19.9 9.3 0.0015 18.5 6.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKX73869.1 - 0.00095 18.7 9.4 0.0023 17.5 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKX73869.1 - 0.008 15.9 10.3 0.018 14.8 7.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EKX73869.1 - 0.014 15.0 12.2 0.041 13.5 8.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nop53 PF07767.6 EKX73869.1 - 0.036 13.0 15.0 0.054 12.4 10.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Ebp2 PF05890.7 EKX73869.1 - 0.16 11.2 8.4 0.34 10.1 5.9 1.5 1 1 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 AF-4 PF05110.8 EKX73869.1 - 0.38 8.5 12.4 0.54 8.0 8.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.7 EKX73869.1 - 1 9.0 13.4 1.6 8.3 9.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-P11 PF03854.9 EKX73869.1 - 1.7 8.1 11.3 4.2 6.9 7.8 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.1 EKX73869.1 - 2.9 7.8 13.5 0.12 12.2 3.5 2.7 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING CoaE PF01121.15 EKX73870.1 - 1.8e-39 135.0 0.0 2.3e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EKX73870.1 - 0.0019 19.0 0.1 0.0029 18.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKX73870.1 - 0.011 16.0 0.4 0.046 14.0 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EKX73870.1 - 0.07 13.0 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EKX73870.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EKX73870.1 - 0.088 12.3 0.4 0.24 10.9 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ArfGap PF01412.13 EKX73871.1 - 1.6e-30 105.2 0.0 3.6e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Apo-CIII PF05778.7 EKX73871.1 - 0.19 11.1 1.5 3.7 7.0 0.2 2.3 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) RNA_pol_Rpb1_5 PF04998.12 EKX73872.1 - 2.2e-84 282.9 0.0 4.3e-84 282.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EKX73872.1 - 3.2e-57 193.0 0.0 6.6e-57 192.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EKX73872.1 - 1.3e-28 99.6 0.2 5.6e-28 97.6 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EKX73872.1 - 9e-19 67.9 7.1 4.5e-18 65.6 0.4 3.6 2 1 1 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EKX73872.1 - 3.2e-13 49.3 0.0 1.2e-12 47.5 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 FAINT PF04385.10 EKX73874.1 - 5.7e-16 58.1 3.3 8.3e-07 28.7 1.2 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX73877.1 - 9.6e-13 48.5 0.0 3.8e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX73877.1 - 3.9e-12 46.1 0.0 1.4e-11 44.3 0.0 2.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX73877.1 - 4.1e-09 36.1 0.3 3.7e-07 29.8 0.1 3.3 3 0 0 3 3 3 1 Putative lysophospholipase FAINT PF04385.10 EKX73877.1 - 9.5e-06 25.3 10.2 0.013 15.3 0.7 4.2 3 0 0 3 3 3 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX73877.1 - 2e-05 24.2 7.1 0.0004 19.9 0.0 2.4 1 1 1 2 2 2 1 Merozoite Antigen Abhydrolase_1 PF00561.15 EKX73877.1 - 0.00035 20.2 0.1 0.01 15.3 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKX73877.1 - 0.01 15.0 0.0 4.6 6.3 0.0 2.9 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EKX73877.1 - 0.069 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EKX73877.1 - 0.098 12.5 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein DUF2305 PF10230.4 EKX73877.1 - 0.13 11.6 0.3 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) RNase_H2-Ydr279 PF09468.5 EKX73879.1 - 0.29 10.2 2.9 0.42 9.7 2.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) BRF1 PF07741.8 EKX73879.1 - 0.34 11.1 6.4 0.73 10.0 4.5 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Bap31 PF05529.7 EKX73879.1 - 3.8 6.9 6.0 6.6 6.1 4.1 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like PRP1_N PF06424.7 EKX73881.1 - 2e-36 125.2 0.8 2e-36 125.2 0.5 3.1 3 0 0 3 3 3 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EKX73881.1 - 8.6e-19 66.3 11.6 0.01 16.3 0.1 10.2 4 3 6 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 EKX73881.1 - 2e-11 44.2 4.4 0.033 14.8 0.7 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EKX73881.1 - 5.1e-10 39.5 9.1 0.0037 17.5 0.2 7.3 4 2 5 9 9 9 3 Tetratricopeptide repeat TPR_21 PF09976.4 EKX73881.1 - 4.3e-05 23.5 3.9 0.0068 16.3 0.6 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF3808 PF10300.4 EKX73881.1 - 0.00087 17.9 0.2 7.8 4.9 0.0 3.9 3 1 1 4 4 4 2 Protein of unknown function (DUF3808) TPR_17 PF13431.1 EKX73881.1 - 0.0019 18.2 1.3 7.3 7.0 0.0 6.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKX73881.1 - 0.0077 16.0 15.1 4.4 7.4 0.1 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 EKX73881.1 - 0.11 12.3 1.3 0.53 10.1 0.0 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF963 PF06131.6 EKX73881.1 - 0.22 10.8 1.1 0.51 9.6 0.8 1.5 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) TPR_12 PF13424.1 EKX73881.1 - 0.44 10.5 7.9 4 7.4 0.4 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EKX73881.1 - 6.5 6.8 9.5 5.3 7.0 0.2 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKX73883.1 - 4.1e-05 23.8 0.8 0.27 11.9 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat VSP PF03302.8 EKX73883.1 - 8e-05 21.4 0.1 8e-05 21.4 0.0 1.5 2 0 0 2 2 2 1 Giardia variant-specific surface protein TPR_19 PF14559.1 EKX73883.1 - 0.00028 21.1 0.1 3.2 8.1 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EKX73883.1 - 0.0023 17.7 0.2 2.1 8.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKX73883.1 - 0.0072 16.9 0.3 1.5 9.5 0.1 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKX73883.1 - 0.012 15.4 0.0 4.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EKX73883.1 - 0.069 12.8 0.1 2.7 7.6 0.0 3.1 3 1 1 4 4 4 0 TPR repeat G-patch PF01585.18 EKX73884.1 - 4e-17 61.7 0.2 7.6e-17 60.8 0.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EKX73884.1 - 3.2e-08 33.3 0.2 3.2e-08 33.3 0.1 1.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site zf-Tim10_DDP PF02953.10 EKX73888.1 - 1.1e-17 63.0 1.2 1.4e-17 62.6 0.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EKX73888.1 - 0.089 12.2 2.2 0.14 11.6 1.6 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) FAST_1 PF06743.10 EKX73890.1 - 0.00014 21.4 13.7 0.13 11.9 0.6 4.9 3 1 0 4 4 4 3 FAST kinase-like protein, subdomain 1 Collagen PF01391.13 EKX73891.1 - 6.2 6.4 37.8 0.19 11.3 8.3 3.1 3 0 0 3 3 3 0 Collagen triple helix repeat (20 copies) Asp PF00026.18 EKX73893.1 - 1.3e-34 119.9 0.7 1.7e-34 119.5 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EKX73893.1 - 0.0044 16.9 0.0 0.04 13.8 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal YlbD_coat PF14071.1 EKX73895.1 - 0.022 14.8 1.1 0.04 13.9 0.7 1.3 1 0 0 1 1 1 0 Putative coat protein AAA_23 PF13476.1 EKX73895.1 - 0.48 10.7 7.3 0.7 10.1 4.8 1.6 1 1 0 1 1 1 0 AAA domain Lipoprotein_20 PF13942.1 EKX73895.1 - 1.2 8.6 4.1 1.9 8.0 2.9 1.2 1 0 0 1 1 1 0 YfhG lipoprotein DUF4110 PF13422.1 EKX73895.1 - 2.8 7.8 5.9 0.79 9.5 2.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) UQ_con PF00179.21 EKX73896.1 - 1.1e-36 125.2 0.0 1.4e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SNF2_N PF00176.18 EKX73897.1 - 2.3e-56 190.7 0.0 6.5e-45 153.1 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EKX73897.1 - 1.2e-11 44.2 0.0 2.9e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKX73897.1 - 0.0005 19.9 0.0 0.0041 16.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit LSM PF01423.17 EKX73898.1 - 2.9e-18 65.1 0.0 3.3e-18 64.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain Ufd2P_core PF10408.4 EKX73900.1 - 1.7e-142 475.8 22.7 2.1e-142 475.5 15.7 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EKX73900.1 - 1.8e-23 82.2 0.3 4.3e-23 81.0 0.2 1.7 1 0 0 1 1 1 1 U-box domain DUF3525 PF12039.3 EKX73900.1 - 0.064 11.7 0.1 5 5.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3525) zf-CCCH PF00642.19 EKX73902.1 - 0.00045 19.8 15.9 0.0012 18.4 0.2 4.2 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pro_isomerase PF00160.16 EKX73903.1 - 1.3e-47 161.8 0.0 2.6e-47 160.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EKX73903.1 - 6.3e-13 48.0 2.3 1.3e-05 24.9 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat HHH_2 PF12826.2 EKX73904.1 - 0.063 13.1 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif TauE PF01925.14 EKX73905.1 - 2e-21 76.5 20.6 2.5e-12 46.7 9.6 2.1 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE Pho88 PF10032.4 EKX73905.1 - 0.064 12.4 0.4 0.52 9.5 0.0 2.5 1 1 1 2 2 2 0 Phosphate transport (Pho88) tRNA-synt_2 PF00152.15 EKX73906.1 - 6.9e-62 209.1 0.0 9.1e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EKX73906.1 - 5.6e-08 32.5 0.5 1.6e-07 31.0 0.2 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EKX73906.1 - 0.00014 21.1 0.1 0.0036 16.5 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA_anti-like PF12869.2 EKX73906.1 - 0.0082 15.6 0.2 0.047 13.1 0.0 2.2 2 1 0 2 2 2 1 tRNA_anti-like DUF1848 PF08902.6 EKX73906.1 - 0.065 12.7 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) PI3_PI4_kinase PF00454.22 EKX73907.1 - 1.6e-28 99.7 0.0 1.3e-26 93.5 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EKX73907.1 - 1.5e-09 37.2 0.6 2.9e-09 36.3 0.4 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Nse4_C PF08743.5 EKX73908.1 - 8.9e-11 41.6 0.0 2.9e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Nse4 C-terminal DUF4057 PF13266.1 EKX73908.1 - 0.07 12.5 0.5 0.12 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) DEAD PF00270.24 EKX73909.1 - 1.8e-41 141.4 0.0 3.2e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKX73909.1 - 1.7e-17 63.0 0.0 4.3e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EKX73909.1 - 7.9e-16 57.3 0.2 2e-15 56.0 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EKX73909.1 - 4.3e-05 23.4 0.2 0.00032 20.5 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Xin PF08043.7 EKX73910.1 - 3e-05 23.3 22.0 24 4.9 0.0 11.6 12 0 0 12 12 12 4 Xin repeat RAMPs PF03787.10 EKX73910.1 - 0.018 14.8 10.5 10 5.8 7.3 3.4 1 1 0 1 1 1 0 RAMP superfamily Pkinase PF00069.20 EKX73911.1 - 1.6e-19 70.0 0.0 5.7e-18 64.9 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain RabGAP-TBC PF00566.13 EKX73911.1 - 1.1e-13 51.2 4.3 3.9e-13 49.3 2.1 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Pkinase_Tyr PF07714.12 EKX73911.1 - 3.4e-13 49.2 0.0 5.3e-12 45.3 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EKX73911.1 - 2.4e-05 23.4 0.0 0.00011 21.2 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Rhodanese PF00581.15 EKX73911.1 - 0.00045 20.5 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain RRM_6 PF14259.1 EKX73913.1 - 2.8e-14 52.8 0.0 4.8e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKX73913.1 - 7.8e-11 41.4 0.3 1.1e-05 24.9 0.1 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX73913.1 - 6.7e-10 38.6 0.2 2.7e-06 27.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.7 EKX73913.1 - 0.02 14.4 0.0 0.056 13.0 0.0 1.8 1 0 0 1 1 1 0 BRCA1-associated protein 2 Sod_Cu PF00080.15 EKX73913.1 - 0.045 13.9 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) LIN37 PF15306.1 EKX73913.1 - 0.097 12.6 5.8 0.25 11.3 4.0 1.7 1 0 0 1 1 1 0 LIN37 U3_snoRNA_assoc PF08297.6 EKX73913.1 - 0.42 10.8 9.9 1.4 9.1 6.9 1.8 1 0 0 1 1 1 0 U3 snoRNA associated YqfQ PF14181.1 EKX73913.1 - 1.2 9.1 7.7 2.7 8.0 5.4 1.6 1 0 0 1 1 1 0 YqfQ-like protein WBS_methylT PF12589.3 EKX73913.1 - 6.3 7.3 16.2 1 9.8 7.1 2.3 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome TSGP1 PF07771.6 EKX73913.1 - 9.7 6.0 11.1 36 4.2 4.7 2.8 3 0 0 3 3 3 0 Tick salivary peptide group 1 SRP9-21 PF05486.7 EKX73914.1 - 4.8e-18 64.6 0.5 6.7e-18 64.2 0.4 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) NMD3 PF04981.8 EKX73915.1 - 7.1e-46 156.2 3.4 1.3e-45 155.4 2.3 1.4 1 0 0 1 1 1 1 NMD3 family FtsJ PF01728.14 EKX73916.1 - 2e-55 187.5 0.2 3.1e-55 186.9 0.2 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Brix PF04427.13 EKX73916.1 - 3.3e-34 118.2 0.6 3.3e-34 118.2 0.4 2.0 2 0 0 2 2 2 1 Brix domain Adaptin_N PF01602.15 EKX73917.1 - 4e-69 233.3 19.2 5.3e-69 232.9 13.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region B2-adapt-app_C PF09066.5 EKX73917.1 - 6e-07 29.3 0.1 2.2e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.1 EKX73917.1 - 0.00025 21.2 0.3 2.1 8.6 0.0 4.0 3 2 1 4 4 4 2 HEAT repeats AAA_6 PF12774.2 EKX73919.1 - 4.2e-42 144.2 0.4 1e-41 142.9 0.3 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 EKX73919.1 - 5e-34 117.4 19.6 5e-34 117.4 13.6 5.1 4 1 1 6 6 6 1 Dynein heavy chain, N-terminal region 2 MT PF12777.2 EKX73919.1 - 7.1e-16 57.8 14.4 7.1e-16 57.8 10.0 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EKX73919.1 - 2.4e-07 30.5 0.0 0.026 14.2 0.0 3.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EKX73919.1 - 4.3e-05 24.3 1.7 0.2 12.4 0.1 5.4 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.1 EKX73919.1 - 0.0075 15.8 0.0 0.4 10.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKX73919.1 - 0.52 10.0 0.1 4.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain zf-RING_UBOX PF13445.1 EKX73920.1 - 1e-14 53.9 5.1 2.6e-14 52.6 3.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EKX73920.1 - 4.4e-07 29.6 4.7 1e-06 28.4 3.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EKX73920.1 - 7.8e-07 28.7 5.4 1.9e-06 27.4 3.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKX73920.1 - 1e-06 28.6 4.1 3.1e-06 27.1 2.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKX73920.1 - 4.2e-06 26.3 4.9 9e-06 25.2 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKX73920.1 - 7.3e-06 25.7 3.3 1.6e-05 24.6 2.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EKX73920.1 - 8.7e-05 22.1 5.9 0.00021 20.8 4.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EKX73920.1 - 0.0003 20.2 3.1 0.001 18.5 2.1 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EKX73920.1 - 0.01 15.4 3.3 0.022 14.3 2.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CLTH PF10607.4 EKX73920.1 - 0.05 13.3 0.1 0.42 10.2 0.1 2.5 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain zf-MIZ PF02891.15 EKX73920.1 - 0.051 13.1 4.7 0.1 12.1 3.3 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 EKX73920.1 - 0.26 11.4 3.3 0.84 9.7 2.3 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EKX73921.1 - 0.0062 16.1 9.0 0.0062 16.1 6.2 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Abhydrolase_6 PF12697.2 EKX73924.1 - 3.7e-15 56.4 0.0 7.5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX73924.1 - 9.6e-14 51.3 0.0 2.1e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family FAINT PF04385.10 EKX73924.1 - 3.2e-13 49.3 10.9 7.4e-05 22.5 0.0 4.2 4 0 0 4 4 4 3 Domain of unknown function, DUF529 Hydrolase_4 PF12146.3 EKX73924.1 - 1.9e-09 37.2 0.5 1.6e-08 34.2 0.2 2.4 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EKX73924.1 - 1.3e-05 24.4 0.0 0.001 18.3 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EKX73924.1 - 0.00041 19.9 0.0 0.016 14.7 0.0 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EKX73924.1 - 0.00072 19.1 0.0 0.01 15.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 EKX73924.1 - 0.0016 17.7 0.1 0.016 14.5 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_2 PF02230.11 EKX73924.1 - 0.0047 16.4 1.1 0.11 11.9 0.1 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 EKX73924.1 - 0.0065 16.0 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.8 EKX73924.1 - 0.0085 15.7 0.1 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.7 EKX73924.1 - 0.014 14.7 0.0 0.032 13.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 EKX73924.1 - 0.02 13.8 1.2 0.038 12.9 0.1 2.0 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase DUF2305 PF10230.4 EKX73924.1 - 0.089 12.1 1.4 0.12 11.7 0.2 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Hydrolase_3 PF08282.7 EKX73926.1 - 3.9e-42 144.5 0.0 4.6e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX73926.1 - 2.4e-09 36.8 0.0 2e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EKX73926.1 - 0.00067 19.8 0.0 0.0024 18.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKX73926.1 - 0.0017 18.8 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PH_7 PF15408.1 EKX73926.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Hydrolase_6 PF13344.1 EKX73926.1 - 0.03 14.1 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EKX73926.1 - 0.078 13.1 0.0 0.87 9.7 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FAINT PF04385.10 EKX73927.1 - 4.2e-14 52.1 6.3 2.6e-08 33.6 0.7 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX73927.1 - 4.5e-06 26.3 1.8 0.0005 19.6 1.3 2.2 1 1 0 1 1 1 1 Merozoite Antigen Neisseria_TspB PF05616.8 EKX73927.1 - 0.58 8.4 10.2 0.9 7.8 7.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Peptidase_C1 PF00112.18 EKX73929.1 - 6.8e-59 199.3 0.1 9.9e-59 198.8 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKX73929.1 - 3.8e-06 27.0 7.9 5.5e-06 26.5 4.6 2.0 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EKX73929.1 - 1.5e-05 23.6 0.1 0.003 16.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family FAD_binding_1 PF00667.15 EKX73930.1 - 8.6e-19 67.8 0.1 6.1e-17 61.8 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain Flavodoxin_1 PF00258.20 EKX73930.1 - 1.2e-13 51.2 0.0 2.6e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EKX73930.1 - 0.0048 17.4 0.0 0.0099 16.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2685 PF10886.3 EKX73930.1 - 0.07 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) zf-Tim10_DDP PF02953.10 EKX73931.1 - 0.0024 17.1 1.8 1.5 8.1 0.0 2.4 2 0 0 2 2 2 2 Tim10/DDP family zinc finger COBRA1 PF06209.8 EKX73932.1 - 0.00074 18.2 0.9 0.0022 16.6 0.1 2.0 2 0 0 2 2 2 1 Cofactor of BRCA1 (COBRA1) Transglut_core PF01841.14 EKX73934.1 - 0.0094 16.1 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily tRNA_int_endo PF01974.12 EKX73936.1 - 1.8e-18 66.0 0.0 2e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain XRN_N PF03159.13 EKX73937.1 - 7.8e-58 195.6 0.0 1.2e-57 195.0 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Nup54 PF13874.1 EKX73938.1 - 1.3e-07 31.3 0.4 1.3e-07 31.3 0.3 1.9 2 1 0 2 2 2 1 Nucleoporin complex subunit 54 Plasmid_stabil PF05016.9 EKX73938.1 - 0.0077 16.6 0.5 0.6 10.5 0.1 2.7 2 0 0 2 2 2 1 Plasmid stabilisation system protein V_ATPase_I PF01496.14 EKX73938.1 - 2.1 6.0 8.6 0.21 9.4 1.6 1.9 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EKX73938.1 - 4 6.9 13.0 1.5 8.3 3.7 2.7 2 1 0 2 2 2 0 IncA protein UQ_con PF00179.21 EKX73939.1 - 7.3e-22 77.3 0.0 8.3e-22 77.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAINT PF04385.10 EKX73940.1 - 8.4e-37 124.8 7.9 7.6e-08 32.0 0.2 5.5 5 0 0 5 5 5 5 Domain of unknown function, DUF529 Saf-Nte_pilin PF09460.5 EKX73940.1 - 0.026 14.3 1.0 25 4.6 0.1 3.9 4 0 0 4 4 4 0 Saf-pilin pilus formation protein FAINT PF04385.10 EKX73941.1 - 1.4e-09 37.6 0.1 4.1e-05 23.3 0.2 2.7 2 0 0 2 2 2 2 Domain of unknown function, DUF529 EMA PF02488.10 EKX73941.1 - 8.9e-07 28.6 1.5 0.002 17.6 0.6 3.4 2 1 1 3 3 3 3 Merozoite Antigen FAINT PF04385.10 EKX73942.1 - 1.3e-08 34.5 0.0 0.00011 21.9 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function, DUF529 ABC_tran PF00005.22 EKX73944.1 - 1.1e-29 103.4 0.0 3.6e-16 59.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 EKX73944.1 - 6.2e-06 26.3 0.2 0.045 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EKX73944.1 - 1.1e-05 25.6 0.3 0.022 14.7 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EKX73944.1 - 2e-05 24.0 2.2 0.1 12.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EKX73944.1 - 0.00014 22.2 5.3 0.11 12.8 0.5 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EKX73944.1 - 0.00021 20.7 0.0 0.065 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKX73944.1 - 0.00023 21.9 0.1 0.14 13.0 0.0 3.3 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 EKX73944.1 - 0.00026 19.8 0.1 0.0039 15.9 0.0 2.1 2 0 0 2 2 2 1 ArgK protein DUF258 PF03193.11 EKX73944.1 - 0.00036 19.7 0.3 0.11 11.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EKX73944.1 - 0.00058 20.1 0.1 0.42 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EKX73944.1 - 0.0007 19.2 0.1 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EKX73944.1 - 0.00086 19.0 0.0 2.3 7.8 0.0 3.0 2 1 0 2 2 2 2 Archaeal ATPase DUF87 PF01935.12 EKX73944.1 - 0.0011 18.8 1.9 0.097 12.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EKX73944.1 - 0.0011 18.4 0.2 0.26 10.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 EKX73944.1 - 0.0014 17.6 0.3 1 8.1 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 EKX73944.1 - 0.0044 17.1 0.0 2.8 8.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 EKX73944.1 - 0.0059 17.0 0.1 4.7 7.7 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein SMC_N PF02463.14 EKX73944.1 - 0.0062 15.7 1.2 0.084 12.0 0.2 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EKX73944.1 - 0.0097 14.9 0.2 6.4 5.7 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain MMR_HSR1 PF01926.18 EKX73944.1 - 0.011 15.7 0.1 0.25 11.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EKX73944.1 - 0.016 14.3 0.2 3.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 EKX73944.1 - 0.016 14.8 0.3 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EKX73944.1 - 0.032 13.8 0.3 9 5.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.8 EKX73944.1 - 0.035 13.0 0.1 0.34 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_NifH PF00142.13 EKX73944.1 - 0.065 12.4 0.1 7 5.7 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Dynamin_N PF00350.18 EKX73944.1 - 0.071 12.9 0.8 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_19 PF13245.1 EKX73944.1 - 0.077 12.7 0.2 16 5.3 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_10 PF12846.2 EKX73944.1 - 0.08 12.3 0.6 12 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EKX73944.1 - 0.17 11.7 0.2 10 6.0 0.1 2.9 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 EKX73944.1 - 0.2 11.3 0.5 7.4 6.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EKX73945.1 - 1.5e-43 148.1 0.1 3.9e-43 146.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKX73945.1 - 2.5e-07 30.9 0.1 6.8e-05 23.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EKX73945.1 - 2.1e-06 27.7 0.0 4.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EKX73945.1 - 7.5e-06 25.7 0.5 7.2e-05 22.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EKX73945.1 - 2.5e-05 23.4 0.0 4.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EKX73945.1 - 2.7e-05 24.0 0.0 0.0023 17.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EKX73945.1 - 4.7e-05 22.4 0.0 9.1e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EKX73945.1 - 9.3e-05 22.4 0.0 0.00029 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EKX73945.1 - 0.00012 22.8 0.0 0.0004 21.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKX73945.1 - 0.0006 20.1 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EKX73945.1 - 0.00068 19.0 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EKX73945.1 - 0.0014 18.3 0.3 0.0029 17.3 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EKX73945.1 - 0.0026 17.7 0.1 0.0073 16.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EKX73945.1 - 0.0031 17.3 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EKX73945.1 - 0.0037 17.4 0.0 0.0085 16.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EKX73945.1 - 0.0041 15.8 0.0 0.0089 14.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus NACHT PF05729.7 EKX73945.1 - 0.0052 16.4 0.1 0.22 11.1 0.0 2.8 2 1 1 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 EKX73945.1 - 0.0074 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin NTPase_1 PF03266.10 EKX73945.1 - 0.0074 16.0 1.6 0.3 10.7 0.2 3.0 2 1 0 2 2 2 1 NTPase Mg_chelatase PF01078.16 EKX73945.1 - 0.012 14.7 0.1 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EKX73945.1 - 0.012 14.9 0.9 0.14 11.5 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EKX73945.1 - 0.012 15.1 0.2 0.03 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EKX73945.1 - 0.013 14.7 0.3 0.081 12.1 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein Arch_ATPase PF01637.13 EKX73945.1 - 0.026 14.2 0.1 0.19 11.3 0.0 2.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_3 PF07726.6 EKX73945.1 - 0.028 14.0 0.0 0.075 12.6 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EKX73945.1 - 0.029 13.2 0.0 0.062 12.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.21 EKX73945.1 - 0.079 12.4 0.1 0.77 9.2 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EKX73945.1 - 0.093 11.5 0.1 0.23 10.2 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EKX73945.1 - 0.094 12.7 0.0 0.32 11.0 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EKX73945.1 - 0.12 12.6 0.2 0.31 11.3 0.1 2.0 1 1 0 1 1 1 0 ABC transporter Syntaxin-6_N PF09177.6 EKX73946.1 - 9.8e-21 73.9 3.6 9.8e-21 73.9 2.5 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EKX73946.1 - 5.2e-09 35.6 2.7 5.2e-09 35.6 1.9 3.2 4 0 0 4 4 4 1 SNARE domain PTE PF02126.13 EKX73946.1 - 0.016 14.2 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family DUF892 PF05974.7 EKX73946.1 - 0.032 14.0 1.9 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF892) NPV_P10 PF05531.7 EKX73946.1 - 0.044 14.0 3.2 0.29 11.4 0.0 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ArsR PF09824.4 EKX73946.1 - 0.12 11.6 2.4 0.34 10.2 0.1 2.2 1 1 0 2 2 2 0 ArsR transcriptional regulator TMF_TATA_bd PF12325.3 EKX73946.1 - 0.15 11.7 7.0 0.17 11.6 0.1 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TBPIP PF07106.8 EKX73946.1 - 0.22 11.0 11.1 0.16 11.5 2.6 2.1 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Helicase_IV_N PF12462.3 EKX73946.1 - 0.24 11.0 1.6 0.29 10.7 0.3 1.7 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal AAA_13 PF13166.1 EKX73946.1 - 0.38 9.1 11.6 0.71 8.2 8.1 1.4 1 1 0 1 1 1 0 AAA domain CHASE3 PF05227.8 EKX73946.1 - 0.43 10.2 4.2 0.34 10.5 0.4 2.3 2 1 0 2 2 2 0 CHASE3 domain ATG16 PF08614.6 EKX73946.1 - 0.47 10.2 12.6 3 7.6 0.9 2.1 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Cauli_AT PF03233.8 EKX73946.1 - 0.49 10.0 6.8 0.57 9.8 2.8 2.1 2 0 0 2 2 2 0 Aphid transmission protein Prefoldin_2 PF01920.15 EKX73946.1 - 1 9.1 8.9 0.58 9.9 1.1 3.2 1 1 2 3 3 3 0 Prefoldin subunit Syntaxin PF00804.20 EKX73946.1 - 1.2 9.2 11.1 7.3 6.8 5.1 2.8 1 1 2 3 3 3 0 Syntaxin DUF1664 PF07889.7 EKX73946.1 - 1.3 8.8 8.9 2.9 7.6 2.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3552 PF12072.3 EKX73946.1 - 1.7 7.8 9.3 0.48 9.5 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) AATF-Che1 PF13339.1 EKX73946.1 - 1.7 8.7 9.1 0.74 9.9 1.7 2.7 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor V_ATPase_I PF01496.14 EKX73946.1 - 3.7 5.2 6.8 5.3 4.7 4.2 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family AKNA PF12443.3 EKX73946.1 - 4 7.5 7.4 0.44 10.5 1.0 2.2 2 1 0 2 2 2 0 AT-hook-containing transcription factor ESSS PF10183.4 EKX73947.1 - 1.3 9.4 3.6 1.1 9.6 0.2 2.5 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) BRX_N PF13713.1 EKX73948.1 - 0.026 13.9 0.3 0.14 11.6 0.0 2.2 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain Rossmann-like PF10727.4 EKX73949.1 - 0.048 13.3 0.1 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain zf-C2HC5 PF06221.8 EKX73949.1 - 8.5 6.2 14.9 0.28 10.9 3.5 3.0 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type mTERF PF02536.9 EKX73951.1 - 3.8e-12 45.4 0.2 1.2e-09 37.2 0.1 2.4 2 0 0 2 2 2 2 mTERF FAINT PF04385.10 EKX73952.1 - 9.1e-26 89.5 11.9 5.5e-05 22.9 0.1 6.6 7 0 0 7 7 7 6 Domain of unknown function, DUF529 NADH-u_ox-rdase PF10785.4 EKX73953.1 - 4 7.7 8.0 14 5.9 0.7 4.1 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit IF3_C PF00707.17 EKX73955.1 - 3.1e-05 23.6 0.2 4.9e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain XPG_I PF00867.13 EKX73956.1 - 1.5e-12 47.3 0.0 3.8e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EKX73956.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 XPG N-terminal domain KH_1 PF00013.24 EKX73957.1 - 0.00015 21.3 0.0 0.58 9.8 0.0 2.7 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 EKX73957.1 - 0.061 12.8 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 KH domain Hydrolase_3 PF08282.7 EKX73959.1 - 6.5e-39 134.0 0.0 8.4e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX73959.1 - 6.8e-07 28.8 0.0 0.0019 17.5 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EKX73959.1 - 0.033 14.3 0.0 0.042 14.0 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Endonuc-FokI_C PF09254.6 EKX73959.1 - 0.077 12.0 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Hydrolase PF00702.21 EKX73959.1 - 0.09 13.1 0.0 0.23 11.8 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SRP54 PF00448.17 EKX73960.1 - 1.8e-77 259.2 0.2 3.2e-77 258.4 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EKX73960.1 - 4e-25 88.0 0.3 4e-25 88.0 0.2 2.7 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.14 EKX73960.1 - 1.2e-13 50.8 2.1 3e-13 49.6 1.5 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EKX73960.1 - 2.9e-06 26.8 0.0 8.2e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 EKX73960.1 - 9.9e-05 21.8 0.0 0.00048 19.5 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 EKX73960.1 - 0.00013 21.8 0.0 0.00031 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EKX73960.1 - 0.00013 20.8 0.0 0.00042 19.1 0.0 1.8 1 1 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EKX73960.1 - 0.00017 21.6 0.1 0.0086 16.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain VirE PF05272.6 EKX73960.1 - 0.00018 21.0 0.0 0.00035 20.1 0.0 1.4 1 0 0 1 1 1 1 Virulence-associated protein E AAA_22 PF13401.1 EKX73960.1 - 0.00037 20.6 0.1 0.0044 17.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EKX73960.1 - 0.00065 19.4 0.0 0.0021 17.7 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EKX73960.1 - 0.0037 16.3 0.0 0.0067 15.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.1 EKX73960.1 - 0.0051 16.4 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EKX73960.1 - 0.0062 16.4 0.0 4.8 7.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain APS_kinase PF01583.15 EKX73960.1 - 0.007 16.0 0.1 0.022 14.3 0.0 1.8 2 0 0 2 2 2 1 Adenylylsulphate kinase KaiC PF06745.8 EKX73960.1 - 0.021 13.9 0.2 0.11 11.5 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_17 PF13207.1 EKX73960.1 - 0.022 15.5 0.0 0.057 14.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Fe-ADH PF00465.14 EKX73960.1 - 0.042 12.4 0.0 0.1 11.2 0.0 1.6 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase PduV-EutP PF10662.4 EKX73960.1 - 0.05 13.0 0.9 6.1 6.3 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 EKX73960.1 - 0.094 12.5 0.3 1.1 9.0 0.1 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EKX73960.1 - 0.11 11.8 0.1 0.4 10.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Methyltransf_24 PF13578.1 EKX73960.1 - 0.13 13.1 0.2 0.42 11.4 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain DUF2209 PF09974.4 EKX73960.1 - 0.16 12.0 0.2 0.16 12.0 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) ArsA_ATPase PF02374.10 EKX73960.1 - 0.97 8.4 5.2 0.6 9.1 0.2 3.2 3 1 0 3 3 3 0 Anion-transporting ATPase FAINT PF04385.10 EKX73962.1 - 0.00011 21.9 6.4 0.0016 18.2 0.7 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 PI3_PI4_kinase PF00454.22 EKX73963.1 - 2.9e-28 98.9 0.0 2e-26 92.9 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAINT PF04385.10 EKX73963.1 - 1.1e-13 50.7 16.4 1.5e-05 24.7 0.3 5.0 4 0 0 4 4 4 3 Domain of unknown function, DUF529 PI3Ka PF00613.15 EKX73963.1 - 1.2e-09 37.6 0.7 3e-09 36.3 0.5 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4448 PF14610.1 EKX73964.1 - 0.019 14.4 0.0 0.048 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EIF_2_alpha PF07541.7 EKX73965.1 - 1.5e-30 105.2 0.0 2.8e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EKX73965.1 - 4.1e-11 42.8 0.4 9.7e-11 41.6 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 EKX73965.1 - 0.0029 17.5 0.3 0.02 14.8 0.0 2.5 2 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 EcKinase PF02958.15 EKX73965.1 - 0.028 13.5 0.2 0.07 12.2 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase RepL PF05732.6 EKX73965.1 - 0.032 13.4 0.6 1.3 8.1 0.2 2.2 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) TPR_12 PF13424.1 EKX73966.1 - 1.3e-19 69.8 8.1 6.1e-09 35.6 2.4 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EKX73966.1 - 7.6e-09 35.0 11.0 4.4e-06 26.2 4.2 2.9 1 1 3 4 4 4 3 TPR repeat TPR_10 PF13374.1 EKX73966.1 - 4.2e-07 29.6 1.3 0.0072 16.2 0.2 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EKX73966.1 - 9.2e-07 28.3 12.1 0.0041 16.9 0.7 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKX73966.1 - 8.2e-06 25.2 19.6 0.00053 19.5 0.0 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKX73966.1 - 9e-06 25.1 4.6 0.0018 17.9 0.2 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.13 EKX73966.1 - 0.001 18.8 0.3 0.001 18.8 0.2 2.8 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 EKX73966.1 - 0.006 16.1 14.9 0.22 11.2 1.3 4.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKX73966.1 - 0.056 14.1 0.6 9 7.1 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKX73966.1 - 0.087 13.3 0.9 33 5.2 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKX73966.1 - 0.12 13.0 0.2 38 5.3 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat FAINT PF04385.10 EKX73968.1 - 1.5e-12 47.2 2.9 9.8e-06 25.3 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX73971.1 - 3.7e-11 42.6 0.0 2.8e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 ABC_tran PF00005.22 EKX73972.1 - 1.3e-29 103.2 0.0 4e-16 59.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 EKX73972.1 - 1.6e-05 24.3 0.7 0.16 11.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EKX73972.1 - 2.1e-05 24.6 0.1 0.03 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 EKX73972.1 - 0.00017 21.8 0.1 0.31 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EKX73972.1 - 0.00022 20.7 0.0 0.064 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EKX73972.1 - 0.00022 21.6 1.4 0.34 11.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EKX73972.1 - 0.00027 21.7 0.0 0.18 12.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EKX73972.1 - 0.00069 19.2 0.2 0.088 12.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EKX73972.1 - 0.00072 19.4 3.3 0.083 12.7 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF87 DUF258 PF03193.11 EKX73972.1 - 0.00079 18.6 0.4 0.2 10.8 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ArgK PF03308.11 EKX73972.1 - 0.00082 18.2 0.8 0.0066 15.2 0.1 2.1 2 0 0 2 2 2 1 ArgK protein AAA_21 PF13304.1 EKX73972.1 - 0.0021 18.0 0.3 0.067 13.1 0.1 4.8 7 0 0 7 7 4 2 AAA domain T2SE PF00437.15 EKX73972.1 - 0.0021 17.0 0.6 0.62 8.9 0.1 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EKX73972.1 - 0.004 16.6 0.4 0.61 9.5 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family SMC_N PF02463.14 EKX73972.1 - 0.0077 15.4 0.2 0.098 11.8 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Miro PF08477.8 EKX73972.1 - 0.01 16.3 0.1 4.3 7.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 EKX73972.1 - 0.011 15.5 4.0 0.23 11.2 0.0 2.7 3 0 0 3 3 2 0 Dynamin family AAA_22 PF13401.1 EKX73972.1 - 0.012 15.7 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EKX73972.1 - 0.013 15.1 0.3 0.96 9.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EKX73972.1 - 0.02 14.8 1.3 0.34 10.8 0.0 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EKX73972.1 - 0.025 13.7 2.3 3.4 6.6 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin NACHT PF05729.7 EKX73972.1 - 0.028 14.0 0.3 7.8 6.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.12 EKX73972.1 - 0.035 13.6 0.1 5.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 EKX73972.1 - 0.052 13.3 1.0 6.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_10 PF12846.2 EKX73972.1 - 0.078 12.3 0.2 14 4.9 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 EKX73972.1 - 0.08 12.5 0.6 3 7.4 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EKX73972.1 - 0.087 13.0 0.0 14 5.8 0.0 3.2 3 0 0 3 3 2 0 RNA helicase AAA_33 PF13671.1 EKX73972.1 - 0.1 12.4 0.1 5.3 6.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EKX73972.1 - 0.14 11.0 0.1 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Peptidase_C1 PF00112.18 EKX73973.1 - 6.5e-48 163.4 2.3 6.5e-48 163.4 1.6 1.6 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EKX73973.1 - 3.7e-07 29.0 0.6 0.00012 20.7 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family DUF1510 PF07423.6 EKX73973.1 - 0.0064 15.8 12.1 0.01 15.2 8.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Inhibitor_I29 PF08246.7 EKX73973.1 - 0.033 14.4 1.0 0.098 12.9 0.5 1.9 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) Peptidase_S49_N PF08496.5 EKX73973.1 - 0.04 13.6 0.5 0.04 13.6 0.4 2.0 1 1 1 2 2 2 0 Peptidase family S49 N-terminal DUF1980 PF09323.5 EKX73973.1 - 0.047 13.4 0.2 0.047 13.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Ndc1_Nup PF09531.5 EKX73973.1 - 1.7 6.9 5.3 2.5 6.4 3.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RVT_1 PF00078.22 EKX73975.1 - 1e-34 119.7 0.1 2.3e-34 118.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PGK PF00162.14 EKX73978.1 - 3e-09 35.9 0.4 3.5e-09 35.6 0.3 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase Lactococcin_972 PF09683.5 EKX73978.1 - 0.15 12.3 2.0 0.2 12.0 1.4 1.2 1 0 0 1 1 1 0 Bacteriocin (Lactococcin_972) G-patch PF01585.18 EKX73980.1 - 7.1e-15 54.5 2.0 1.5e-14 53.4 1.4 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EKX73980.1 - 0.018 14.8 0.6 0.018 14.8 0.4 2.0 2 0 0 2 2 2 0 DExH-box splicing factor binding site Gar1 PF04410.9 EKX73981.1 - 1.8e-25 89.1 1.2 5.6e-25 87.5 0.7 1.8 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Ribosomal_L2 PF00181.18 EKX73982.1 - 0.11 12.4 0.5 0.33 10.9 0.5 1.6 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain TFIIS_C PF01096.13 EKX73983.1 - 1.8e-13 49.8 2.4 1.8e-13 49.8 1.6 2.4 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) DUF2757 PF10955.3 EKX73983.1 - 0.016 15.4 4.5 0.73 10.0 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2757) zf-3CxxC PF13695.1 EKX73983.1 - 0.04 14.1 7.1 2.4 8.4 3.7 2.9 1 1 1 2 2 2 0 Zinc-binding domain Lar_restr_allev PF14354.1 EKX73983.1 - 0.059 13.6 4.9 0.32 11.3 0.3 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar DUF2724 PF10893.3 EKX73983.1 - 0.13 12.1 0.5 0.23 11.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) E7 PF00527.13 EKX73983.1 - 0.24 11.5 5.3 1.2 9.3 0.0 2.8 3 1 0 3 3 2 0 E7 protein, Early protein Baculo_LEF5_C PF11792.3 EKX73983.1 - 0.28 10.6 9.1 0.03 13.6 2.3 2.4 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Zn_Tnp_IS1595 PF12760.2 EKX73983.1 - 0.28 10.9 5.1 0.24 11.2 0.8 2.6 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Ribosomal_L44 PF00935.14 EKX73983.1 - 0.49 10.4 5.0 3.3 7.7 0.2 2.9 3 0 0 3 3 3 0 Ribosomal protein L44 Rpr2 PF04032.11 EKX73983.1 - 0.66 9.8 3.3 1.8 8.4 0.4 2.6 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1610 PF07754.6 EKX73983.1 - 1.3 9.2 5.7 25 5.0 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) DNA_RNApol_7kD PF03604.8 EKX73983.1 - 1.4 8.4 10.3 11 5.5 0.2 3.7 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit PHD PF00628.24 EKX73983.1 - 1.7 8.4 6.9 3.1 7.5 0.8 2.8 3 0 0 3 3 3 0 PHD-finger Zn-ribbon_8 PF09723.5 EKX73983.1 - 1.7 8.6 8.8 13 5.8 0.1 3.6 4 0 0 4 4 3 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.10 EKX73983.1 - 1.9 8.1 0.0 1.9 8.1 0.0 3.5 5 0 0 5 5 5 0 Sec23/Sec24 zinc finger DZR PF12773.2 EKX73983.1 - 4.9 7.0 9.3 4.9e+02 0.6 6.4 3.2 1 1 0 1 1 1 0 Double zinc ribbon RNA_POL_M_15KD PF02150.11 EKX73983.1 - 6.9 6.4 6.7 33 4.2 0.0 3.9 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit Tnp_zf-ribbon_2 PF13842.1 EKX73983.1 - 7.9 6.9 7.3 72 3.9 0.3 3.5 4 0 0 4 4 4 0 DDE_Tnp_1-like zinc-ribbon NOB1_Zn_bind PF08772.6 EKX73983.1 - 9.3 6.1 7.6 3.4 7.5 0.2 3.0 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.1 EKX73983.1 - 9.3 5.8 8.5 5.8 6.5 0.1 2.8 3 0 0 3 3 2 0 zinc-ribbon domain PTH2 PF01981.11 EKX73984.1 - 3.9e-43 145.8 0.0 5e-43 145.4 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 UCR_14kD PF02271.11 EKX73985.1 - 1.5e-13 50.4 0.0 1.9e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Hydrolase_3 PF08282.7 EKX73986.1 - 1.1e-25 90.7 0.0 1.8e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKX73986.1 - 0.00026 20.3 0.0 0.022 14.0 0.0 2.7 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase FAINT PF04385.10 EKX73986.1 - 0.0018 18.0 0.8 0.0048 16.7 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function, DUF529 HAD PF12710.2 EKX73986.1 - 0.064 13.4 0.0 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GMP_synt_C PF00958.17 EKX73987.1 - 4.1e-27 93.7 0.0 1.3e-26 92.1 0.1 1.8 2 0 0 2 2 2 1 GMP synthase C terminal domain GATase PF00117.23 EKX73987.1 - 1.8e-24 86.2 0.0 3.7e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EKX73987.1 - 1e-06 27.8 0.1 7.2e-06 25.0 0.0 2.1 2 0 0 2 2 2 1 NAD synthase Peptidase_C26 PF07722.8 EKX73987.1 - 0.0014 18.0 0.1 0.01 15.3 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 Asn_synthase PF00733.16 EKX73987.1 - 0.0017 17.9 0.0 0.0042 16.6 0.0 1.6 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 EKX73987.1 - 0.002 16.7 0.0 0.0031 16.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Thioredoxin PF00085.15 EKX73988.1 - 2.2e-52 175.0 0.5 6.7e-31 106.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EKX73988.1 - 1.3e-15 57.5 3.3 1.6e-07 31.5 0.1 4.4 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.1 EKX73988.1 - 2.7e-12 46.8 0.0 7.3e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EKX73988.1 - 1.1e-11 44.6 2.9 0.00021 21.3 0.1 4.7 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EKX73988.1 - 4e-09 36.3 1.3 0.0017 18.3 0.1 2.6 2 1 0 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EKX73988.1 - 9.9e-06 25.1 0.0 0.0079 15.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.1 EKX73988.1 - 0.00036 20.2 0.2 1.1 9.1 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin domain TraF PF13728.1 EKX73988.1 - 0.00057 19.4 0.2 1.4 8.3 0.1 2.8 1 1 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 EKX73988.1 - 0.013 15.5 4.0 1.8 8.5 0.3 3.5 2 2 2 4 4 4 0 Thioredoxin LcrR PF09621.5 EKX73988.1 - 0.016 14.4 0.0 4.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Type III secretion system regulator (LcrR) Thioredoxin_5 PF13743.1 EKX73988.1 - 0.08 12.5 0.1 22 4.5 0.0 3.1 2 1 1 3 3 3 0 Thioredoxin Fucose_iso_N2 PF07882.7 EKX73989.1 - 0.15 11.7 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain FAINT PF04385.10 EKX73990.1 - 4.3e-05 23.2 1.7 6.9e-05 22.6 0.7 1.8 1 1 0 1 1 1 1 Domain of unknown function, DUF529 RRM_1 PF00076.17 EKX73992.1 - 2.8e-31 106.9 0.0 3e-18 65.1 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX73992.1 - 4.6e-20 71.3 0.0 3.3e-13 49.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX73992.1 - 1.8e-11 43.6 0.0 8.1e-10 38.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKX73992.1 - 1.3e-07 31.4 0.1 0.02 14.7 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EKX73992.1 - 0.0049 16.6 0.1 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif FAINT PF04385.10 EKX73993.1 - 3.2e-12 46.1 4.5 1.2e-05 24.9 1.2 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Phage_head_chap PF11113.3 EKX73993.1 - 0.032 14.1 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 Head assembly gene product DUF749 PF05370.6 EKX73994.1 - 0.027 14.3 0.3 0.075 12.9 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF749) Serglycin PF04360.7 EKX73996.1 - 0.27 10.9 7.0 0.71 9.5 4.9 1.6 1 0 0 1 1 1 0 Serglycin Macoilin PF09726.4 EKX73996.1 - 8.8 4.4 8.6 14 3.8 6.0 1.2 1 0 0 1 1 1 0 Transmembrane protein SNF2_N PF00176.18 EKX73997.1 - 2.4e-67 226.8 1.2 4.4e-67 225.9 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 EKX73997.1 - 1.4e-22 79.1 6.3 6.7e-11 41.6 0.1 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EKX73997.1 - 1.1e-15 57.2 0.0 3.1e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EKX73997.1 - 2e-13 49.8 0.2 3.9e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EKX73997.1 - 3.3e-08 33.5 0.0 3.5e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EKX73997.1 - 4.7e-07 29.4 0.0 1.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKX73997.1 - 0.0068 16.5 0.1 0.11 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Mtf2_C PF14061.1 EKX73997.1 - 0.077 12.8 0.1 1.2 9.0 0.0 2.6 3 0 0 3 3 3 0 Polycomb-like MTF2 factor 2 FAINT PF04385.10 EKX73999.1 - 9.3e-08 31.8 3.6 0.00082 19.1 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Tho2 PF11262.3 EKX73999.1 - 0.04 12.9 0.2 0.062 12.3 0.1 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Phage_T4_Ndd PF06591.6 EKX73999.1 - 0.082 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) Nucleoporin_FG PF13634.1 EKX74001.1 - 6.7e-31 106.8 202.6 5.7e-08 32.9 23.1 9.0 2 2 5 7 7 7 7 Nucleoporin FG repeat region XPC-binding PF09280.6 EKX74004.1 - 4.7e-21 73.9 8.2 4.7e-21 73.9 5.7 2.2 2 0 0 2 2 2 1 XPC-binding domain UBA PF00627.26 EKX74004.1 - 1.2e-17 63.1 8.9 4.6e-10 39.0 0.6 3.6 4 0 0 4 4 4 2 UBA/TS-N domain ubiquitin PF00240.18 EKX74004.1 - 1.2e-11 43.8 2.1 2.4e-11 42.8 1.4 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKX74004.1 - 2.1e-07 30.5 2.2 4.2e-07 29.5 1.5 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EKX74004.1 - 0.00099 19.2 0.1 0.0019 18.3 0.1 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rap1_C PF11626.3 EKX74004.1 - 0.0053 16.6 0.0 0.11 12.3 0.0 2.7 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF4012 PF13196.1 EKX74004.1 - 0.016 15.3 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) UBA_3 PF09288.5 EKX74004.1 - 0.042 13.4 0.0 6.7 6.3 0.0 3.0 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.1 EKX74004.1 - 0.065 13.1 0.5 0.14 12.0 0.3 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ub-RnfH PF03658.9 EKX74004.1 - 0.11 12.4 0.4 0.25 11.2 0.3 1.6 1 0 0 1 1 1 0 RnfH family Ubiquitin ArsC PF03960.10 EKX74004.1 - 0.16 12.0 1.2 1.2 9.2 0.2 2.4 2 0 0 2 2 2 0 ArsC family KH_1 PF00013.24 EKX74005.1 - 9.1e-11 41.2 0.8 4.9e-05 22.9 0.0 5.8 6 0 0 6 6 6 1 KH domain SLS PF14611.1 EKX74005.1 - 0.00039 19.8 7.1 0.012 15.0 0.0 3.7 3 0 0 3 3 3 2 Mitochondrial inner-membrane-bound regulator KH_3 PF13014.1 EKX74005.1 - 0.00046 19.7 0.5 0.085 12.5 0.1 3.5 3 0 0 3 3 3 1 KH domain TAFII55_N PF04658.8 EKX74005.1 - 0.0057 16.1 0.4 0.034 13.6 0.0 2.3 2 0 0 2 2 2 1 TAFII55 protein conserved region KH_4 PF13083.1 EKX74005.1 - 0.068 12.8 0.2 0.35 10.5 0.1 2.3 1 0 0 1 1 1 0 KH domain FlxA PF14282.1 EKX74005.1 - 0.34 10.8 5.7 5.4 7.0 1.8 2.7 1 1 1 2 2 2 0 FlxA-like protein Proteasome PF00227.21 EKX74007.1 - 3.9e-49 166.5 0.2 4.6e-49 166.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Peptidase_C1 PF00112.18 EKX74010.1 - 4.1e-27 95.5 0.3 7e-27 94.7 0.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKX74010.1 - 0.00063 19.9 0.8 0.0014 18.8 0.5 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) ABC2_membrane_3 PF12698.2 EKX74010.1 - 0.18 10.7 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein EMA PF02488.10 EKX74011.1 - 0.0052 16.2 0.5 0.21 11.0 0.6 2.0 1 1 1 2 2 2 2 Merozoite Antigen FAINT PF04385.10 EKX74011.1 - 0.04 13.7 0.1 0.23 11.3 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function, DUF529 FAINT PF04385.10 EKX74012.1 - 2.1e-16 59.4 14.8 2.9e-06 27.0 0.1 4.6 4 1 1 5 5 5 3 Domain of unknown function, DUF529 FAINT PF04385.10 EKX74013.1 - 0.00011 22.0 1.0 0.0023 17.7 0.1 3.0 3 1 0 3 3 3 1 Domain of unknown function, DUF529 SRP_SPB PF02978.14 EKX74014.1 - 0.011 16.0 0.2 0.046 13.9 0.0 2.1 2 0 0 2 2 2 0 Signal peptide binding domain Ras PF00071.17 EKX74015.1 - 2.5e-58 196.0 0.1 3e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKX74015.1 - 4.5e-18 65.8 0.0 6.6e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKX74015.1 - 5.2e-12 45.3 0.0 6.5e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKX74015.1 - 4.8e-06 26.5 0.0 8.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKX74015.1 - 6.8e-05 22.1 0.0 8.4e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKX74015.1 - 0.00036 20.0 0.0 0.0018 17.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DNA_pol_E_B PF04042.11 EKX74015.1 - 0.027 13.7 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B AAA_22 PF13401.1 EKX74015.1 - 0.03 14.4 0.0 0.089 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EKX74015.1 - 0.041 13.4 0.0 0.082 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EKX74015.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF3391 PF11871.3 EKX74016.1 - 0.21 11.7 4.6 0.34 11.1 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) RRM_1 PF00076.17 EKX74017.1 - 4.3e-33 112.7 0.8 4.9e-16 58.1 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX74017.1 - 5e-24 84.0 0.1 1.5e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX74017.1 - 1.1e-08 34.8 0.1 7.7e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKX74017.1 - 2.2e-05 24.2 0.3 0.12 12.2 0.1 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EKX74017.1 - 0.0004 20.0 2.0 0.41 10.4 0.2 2.7 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 EKX74017.1 - 0.012 15.0 2.9 1.5 8.3 0.0 3.0 2 1 0 2 2 2 0 Ribonuclease B OB domain DUF1509 PF07420.6 EKX74017.1 - 2.4 7.3 19.4 1.7 7.8 12.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) RIO1 PF01163.17 EKX74018.1 - 1.4e-65 220.2 0.3 3e-65 219.1 0.2 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EKX74018.1 - 0.0015 18.3 0.0 0.022 14.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family CK_II_beta PF01214.13 EKX74019.1 - 8.6e-67 224.2 1.4 1.1e-66 223.8 1.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit IBR PF01485.16 EKX74019.1 - 0.069 13.0 1.1 0.24 11.2 0.5 2.1 2 1 0 2 2 2 0 IBR domain Prok-RING_1 PF14446.1 EKX74019.1 - 0.52 10.0 4.6 3.3 7.5 0.1 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Hat1_N PF10394.4 EKX74020.1 - 0.041 13.9 1.5 0.18 11.8 1.0 1.9 1 1 1 2 2 2 0 Histone acetyl transferase HAT1 N-terminus Baculo_PEP_C PF04513.7 EKX74020.1 - 0.16 11.8 0.2 9.4 6.0 0.0 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_17 PF13207.1 EKX74021.1 - 5.5e-07 30.4 0.1 1.9e-06 28.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKX74021.1 - 4.3e-05 23.6 0.1 0.00011 22.2 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EKX74021.1 - 0.0002 21.6 0.1 0.00076 19.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EKX74021.1 - 0.00021 21.5 0.0 0.0023 18.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad51 PF08423.6 EKX74021.1 - 0.00061 18.7 0.1 0.0016 17.3 0.0 1.7 1 1 0 1 1 1 1 Rad51 AAA_14 PF13173.1 EKX74021.1 - 0.00085 19.2 0.1 0.0028 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKX74021.1 - 0.0012 18.8 0.0 0.0029 17.6 0.0 1.6 1 1 1 2 2 1 1 AAA ATPase domain AAA_33 PF13671.1 EKX74021.1 - 0.01 15.7 0.0 0.028 14.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EKX74021.1 - 0.011 15.1 0.0 0.029 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EKX74021.1 - 0.012 15.7 0.0 0.042 14.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_5 PF07728.9 EKX74021.1 - 0.015 15.0 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.11 EKX74021.1 - 0.018 14.3 0.1 0.24 10.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein RuvB_N PF05496.7 EKX74021.1 - 0.02 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 EKX74021.1 - 0.021 15.1 0.2 0.04 14.2 0.2 1.8 1 1 0 1 1 1 0 ABC transporter DUF87 PF01935.12 EKX74021.1 - 0.039 13.7 0.2 0.21 11.4 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function DUF87 T2SE PF00437.15 EKX74021.1 - 0.039 12.8 0.0 0.073 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 EKX74021.1 - 0.045 13.4 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CobU PF02283.11 EKX74021.1 - 0.082 12.3 0.0 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_24 PF13479.1 EKX74021.1 - 0.096 12.2 0.1 4.9 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EKX74021.1 - 0.11 11.6 0.6 0.27 10.3 0.0 1.8 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.12 EKX74021.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.10 EKX74022.1 - 2e-07 30.0 10.8 0.00014 20.6 5.6 2.9 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein eIF-5a PF01287.15 EKX74023.1 - 6.6e-23 80.4 0.0 9.3e-23 79.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 EKX74023.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 EKX74023.1 - 0.042 13.5 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 KOW motif zf-Tim10_DDP PF02953.10 EKX74024.1 - 9.7e-20 69.6 0.0 1.2e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cyto_heme_lyase PF01265.12 EKX74025.1 - 4.7e-60 203.3 0.0 5.5e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase KH_1 PF00013.24 EKX74026.1 - 4.8e-07 29.3 0.6 1.6e-06 27.6 0.4 1.9 1 0 0 1 1 1 1 KH domain FlhE PF06366.8 EKX74026.1 - 0.011 15.6 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 Flagellar protein FlhE DUF508 PF04370.7 EKX74026.1 - 0.015 14.8 0.0 0.047 13.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF508) KH_3 PF13014.1 EKX74026.1 - 0.031 13.9 0.5 0.084 12.5 0.3 1.8 1 0 0 1 1 1 0 KH domain Reticulon PF02453.12 EKX74027.1 - 8.3e-09 35.2 3.7 1.1e-08 34.8 2.6 1.2 1 0 0 1 1 1 1 Reticulon Pex24p PF06398.6 EKX74027.1 - 2.6 6.7 7.2 0.067 11.9 0.7 1.5 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF639 PF04842.7 EKX74027.1 - 2.7 6.0 4.9 0.17 9.9 0.2 1.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Med7 PF05983.6 EKX74029.1 - 4.1e-15 55.9 0.6 5.4e-15 55.5 0.4 1.1 1 0 0 1 1 1 1 MED7 protein Peptidase_S37 PF05576.6 EKX74029.1 - 0.029 12.8 0.0 0.032 12.6 0.0 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 MCM_N PF14551.1 EKX74029.1 - 0.095 13.1 0.8 0.22 12.0 0.6 1.6 1 1 0 1 1 1 0 MCM N-terminal domain Ribosomal_L4 PF00573.17 EKX74030.1 - 4.6e-51 172.9 0.0 6.8e-51 172.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family GN3L_Grn1 PF08701.6 EKX74030.1 - 1.3 8.9 6.0 0.78 9.6 0.7 2.4 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase MobB PF03205.9 EKX74033.1 - 0.00012 21.8 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DAP3 PF10236.4 EKX74033.1 - 0.0095 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_17 PF13207.1 EKX74033.1 - 0.014 16.2 0.0 0.03 15.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKX74033.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.5 EKX74033.1 - 0.057 12.6 0.0 0.091 11.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_10 PF12846.2 EKX74033.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Poty_PP PF08440.5 EKX74035.1 - 0.0049 15.9 0.0 0.0061 15.6 0.0 1.1 1 0 0 1 1 1 1 Potyviridae polyprotein RPAP3_C PF13877.1 EKX74035.1 - 0.055 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 COG5 PF10392.4 EKX74037.1 - 0.003 17.5 5.4 0.0069 16.3 0.1 3.1 3 0 0 3 3 3 1 Golgi transport complex subunit 5 RNase_PH PF01138.16 EKX74038.1 - 5.4e-10 39.7 0.1 9.5e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EKX74038.1 - 0.078 12.9 0.1 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DNA_pol_B PF00136.16 EKX74039.1 - 2.1e-130 435.6 0.2 5.3e-130 434.3 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EKX74039.1 - 3.8e-75 252.7 1.9 5.8e-75 252.1 1.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EKX74039.1 - 8.5e-08 32.0 1.2 6.4e-07 29.2 1.1 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Noc2 PF03715.8 EKX74040.1 - 7.2e-74 248.3 3.4 1.8e-73 247.0 2.4 1.7 1 0 0 1 1 1 1 Noc2p family CwfJ_C_1 PF04677.10 EKX74041.1 - 3.5e-25 87.9 2.0 6e-25 87.2 1.4 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.17 EKX74041.1 - 1.6e-06 27.6 0.0 5.4e-06 25.9 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX74041.1 - 1.8e-05 24.6 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CHCH PF06747.8 EKX74043.1 - 0.0016 18.2 0.7 0.0022 17.8 0.5 1.2 1 0 0 1 1 1 1 CHCH domain Tricho_coat PF05892.6 EKX74044.1 - 0.081 12.1 0.1 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Trichovirus coat protein Oxidored_molyb PF00174.14 EKX74044.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain Syja_N PF02383.13 EKX74045.1 - 5.5e-73 245.5 0.2 8.7e-73 244.8 0.1 1.2 1 0 0 1 1 1 1 SacI homology domain DUF1974 PF09317.6 EKX74045.1 - 0.22 10.8 0.2 0.45 9.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1974) Cyclin_N PF00134.18 EKX74046.1 - 0.00099 18.6 2.7 0.005 16.3 0.3 2.6 1 1 1 2 2 2 1 Cyclin, N-terminal domain RNase_PH PF01138.16 EKX74048.1 - 1.9e-05 25.0 0.4 3.3e-05 24.2 0.3 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EKX74048.1 - 6e-05 22.9 0.1 0.00014 21.7 0.1 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF3855 PF12967.2 EKX74048.1 - 0.043 13.3 0.0 0.093 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) DUF1391 PF07151.7 EKX74048.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) Proteasome PF00227.21 EKX74049.1 - 1.8e-48 164.3 0.2 2.3e-48 164.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EKX74049.1 - 0.0013 17.9 0.0 0.0052 16.0 0.0 2.0 2 0 0 2 2 2 1 Proteasome beta subunits C terminal zf-RING_5 PF14634.1 EKX74050.1 - 0.013 15.1 9.4 0.013 15.1 6.5 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-DNA_Pol PF08996.5 EKX74050.1 - 0.016 14.6 1.0 0.029 13.7 0.7 1.3 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Sigma70_r1_1 PF03979.9 EKX74050.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-70 factor, region 1.1 zf-C2H2 PF00096.21 EKX74050.1 - 0.2 12.0 0.1 0.2 12.0 0.1 3.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKX74050.1 - 0.74 10.2 0.1 0.74 10.2 0.1 3.2 2 1 1 3 3 3 0 C2H2-type zinc finger zf-C3HC4 PF00097.20 EKX74050.1 - 1.6 8.4 7.8 3 7.5 4.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKX74050.1 - 4.3 7.4 8.6 18 5.4 6.0 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKX74050.1 - 7.3 6.5 10.4 3.1 7.6 5.2 1.8 1 1 1 2 2 2 0 Ring finger domain BRCA-2_OB1 PF09103.5 EKX74051.1 - 0.0061 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Rpr2 PF04032.11 EKX74056.1 - 6.5e-21 74.0 1.4 8.9e-21 73.5 1.0 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF164 PF02591.10 EKX74056.1 - 0.053 13.3 0.4 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 Putative zinc ribbon domain Fer4_8 PF13183.1 EKX74056.1 - 0.062 13.3 1.8 0.15 12.0 1.3 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain DUF2683 PF10884.3 EKX74056.1 - 0.13 12.1 0.2 0.39 10.6 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2683) Fer4_9 PF13187.1 EKX74056.1 - 0.68 10.2 4.7 2.5 8.4 3.2 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain WD40 PF00400.27 EKX74058.1 - 2.5e-07 30.3 8.3 8.1e-05 22.3 0.1 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat Sec16_C PF12931.2 EKX74058.1 - 9.4e-05 22.2 0.0 0.00027 20.7 0.0 1.9 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 E1-E2_ATPase PF00122.15 EKX74061.1 - 1.6e-19 69.8 0.4 4.7e-19 68.3 0.3 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EKX74061.1 - 1e-16 61.9 0.0 1.9e-15 57.8 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKX74061.1 - 2.1e-16 60.6 0.0 6.3e-16 59.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKX74061.1 - 0.0011 18.8 0.1 0.0037 17.1 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EKX74061.1 - 0.11 11.9 0.2 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus DEAD PF00270.24 EKX74062.1 - 9.6e-25 87.0 5.4 3.5e-23 81.9 0.1 2.2 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EKX74062.1 - 3.3e-16 58.8 0.3 1.2e-15 57.0 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKX74062.1 - 4.1e-06 26.7 1.2 1.2e-05 25.1 0.0 2.0 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EKX74062.1 - 0.0014 17.4 3.8 0.0014 17.4 2.7 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Spore_GerQ PF09671.5 EKX74062.1 - 0.0031 17.1 0.0 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 Spore coat protein (Spore_GerQ) DUF1744 PF08490.7 EKX74062.1 - 0.0033 16.0 1.0 0.0058 15.2 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DUF2115 PF09888.4 EKX74062.1 - 0.059 13.4 4.4 0.089 12.8 0.4 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) Fe-ADH PF00465.14 EKX74062.1 - 0.076 11.6 0.1 0.56 8.7 0.0 2.1 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase ArsC PF03960.10 EKX74062.1 - 0.87 9.6 5.9 0.25 11.4 1.5 2.1 2 0 0 2 2 2 0 ArsC family Ribosomal_L31e PF01198.14 EKX74063.1 - 2.3e-37 126.4 3.9 2.9e-37 126.2 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e HEAT PF02985.17 EKX74064.1 - 1.5e-07 30.8 0.6 0.6 10.3 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat Pkinase PF00069.20 EKX74064.1 - 1.3e-05 24.4 0.0 2.8e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Vac14_Fab1_bd PF12755.2 EKX74064.1 - 0.00014 22.1 1.7 0.63 10.4 0.1 3.8 1 1 3 4 4 4 3 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 EKX74064.1 - 0.0037 17.2 0.0 15 5.6 0.0 3.5 3 0 0 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation CLASP_N PF12348.3 EKX74064.1 - 0.0038 16.6 0.1 0.07 12.4 0.0 2.1 1 1 1 2 2 2 2 CLASP N terminal Cnd1 PF12717.2 EKX74064.1 - 0.021 14.7 4.1 0.21 11.4 0.1 3.1 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF2373 PF10180.4 EKX74064.1 - 0.038 13.5 0.0 0.095 12.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Cofilin_ADF PF00241.15 EKX74065.1 - 1.5e-09 37.7 0.0 1.9e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RRM_1 PF00076.17 EKX74066.1 - 3.6e-21 74.5 0.0 5.1e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX74066.1 - 3.3e-15 55.8 0.0 4.7e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX74066.1 - 2.7e-09 36.7 0.0 3.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKX74066.1 - 0.042 13.6 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Prefoldin PF02996.12 EKX74067.1 - 1.5e-21 76.2 0.1 1.9e-21 75.9 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit KxDL PF10241.4 EKX74067.1 - 0.011 15.5 0.3 0.055 13.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein BLOC1_2 PF10046.4 EKX74067.1 - 0.026 14.6 0.5 2.7 8.1 0.1 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.15 EKX74067.1 - 0.094 12.4 0.3 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit Orbi_NS3 PF01616.11 EKX74068.1 - 0.17 10.8 0.0 0.41 9.5 0.0 1.7 1 0 0 1 1 1 0 Orbivirus NS3 DUF2637 PF10935.3 EKX74068.1 - 1 9.2 6.2 27 4.6 4.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2637) DUF912 PF06024.7 EKX74069.1 - 0.0071 16.3 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 EKX74069.1 - 0.054 13.1 0.1 0.14 11.8 0.1 1.6 1 1 0 1 1 1 0 TMEM154 protein family p25-alpha PF05517.7 EKX74071.1 - 8.5e-24 84.5 0.0 9.4e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 p25-alpha DUF4250 PF14056.1 EKX74071.1 - 0.0036 16.9 0.7 0.026 14.2 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4250) OSCP PF00213.13 EKX74072.1 - 1.1e-42 145.8 0.1 1.3e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit TRAPPC-Trs85 PF12739.2 EKX74075.1 - 2.6e-13 49.4 0.5 4.5e-13 48.6 0.3 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit HSP90 PF00183.13 EKX74076.1 - 4.9e-128 427.8 19.3 8.8e-128 426.9 9.8 4.0 2 1 1 4 4 4 2 Hsp90 protein HATPase_c_3 PF13589.1 EKX74076.1 - 3.7e-12 46.0 0.2 3.7e-12 46.0 0.2 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EKX74076.1 - 9.4e-08 31.7 0.0 2.6e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SMI1_KNR4 PF09346.5 EKX74076.1 - 0.25 11.3 7.7 3.6 7.6 1.0 3.3 3 1 0 3 3 3 0 SMI1 / KNR4 family (SUKH-1) ARL2_Bind_BART PF11527.3 EKX74076.1 - 0.28 11.0 8.8 3.9 7.2 0.1 4.3 4 0 0 4 4 4 0 The ARF-like 2 binding protein BART ACDC PF14733.1 EKX74077.1 - 2.4e-13 49.9 1.3 2.4e-13 49.9 0.9 1.5 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.15 EKX74077.1 - 9.4e-10 38.4 0.2 1.9e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 AP2 domain Fumble PF03630.9 EKX74078.1 - 2.8e-22 79.0 0.1 5.5e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Fumble SNF2_N PF00176.18 EKX74079.1 - 6.7e-79 264.7 1.5 3.4e-78 262.4 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 EKX74079.1 - 3.8e-30 104.0 1.0 1.1e-29 102.5 0.7 1.8 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.26 EKX74079.1 - 1.9e-17 62.8 0.0 6.3e-17 61.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKX74079.1 - 4.6e-10 39.6 1.1 3.4e-09 36.8 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EKX74079.1 - 6e-07 29.1 0.1 3.6e-06 26.5 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EKX74079.1 - 0.014 15.2 3.2 0.017 14.9 0.1 2.8 4 1 0 4 4 4 0 AAA domain SRR1 PF07985.7 EKX74080.1 - 3.6e-05 23.5 0.0 7.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 SRR1 AAA PF00004.24 EKX74081.1 - 5.5e-96 317.8 0.0 5.1e-47 159.3 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EKX74081.1 - 3.5e-22 78.1 0.1 9.7e-22 76.7 0.1 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EKX74081.1 - 2.6e-12 46.2 0.0 3.5e-05 22.9 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EKX74081.1 - 2.9e-12 46.9 0.2 0.00021 21.3 0.0 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.9 EKX74081.1 - 4.7e-12 46.1 0.0 4.4e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EKX74081.1 - 7.1e-12 45.4 0.0 6.7e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EKX74081.1 - 8.2e-12 46.0 0.0 4.9e-05 24.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EKX74081.1 - 1.1e-11 44.9 0.1 0.00046 20.3 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EKX74081.1 - 8.3e-11 41.7 0.4 8.7e-06 25.5 0.0 3.4 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.12 EKX74081.1 - 2e-09 36.9 0.0 4.1e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 EKX74081.1 - 7.9e-09 35.4 0.0 0.002 18.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EKX74081.1 - 1.5e-08 33.7 0.0 0.00057 18.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 EKX74081.1 - 5.2e-08 33.2 0.1 0.011 16.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EKX74081.1 - 6.4e-08 31.9 0.0 0.0046 16.0 0.0 2.6 2 1 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EKX74081.1 - 7e-08 32.1 2.6 0.11 11.9 0.0 4.1 2 2 2 4 4 4 2 AAA domain Mg_chelatase PF01078.16 EKX74081.1 - 7.3e-07 28.5 0.2 0.03 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EKX74081.1 - 8.2e-07 28.6 2.1 0.018 14.7 0.2 3.1 3 0 0 3 3 3 2 Part of AAA domain RNA_helicase PF00910.17 EKX74081.1 - 8.7e-07 29.0 0.0 0.015 15.4 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Arch_ATPase PF01637.13 EKX74081.1 - 1.4e-06 28.2 0.0 0.065 12.9 0.0 3.7 2 2 2 4 4 4 2 Archaeal ATPase IstB_IS21 PF01695.12 EKX74081.1 - 1.6e-06 27.6 0.0 0.047 13.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 EKX74081.1 - 5e-06 26.2 0.0 0.39 10.3 0.0 3.9 3 1 0 4 4 4 2 NACHT domain AAA_28 PF13521.1 EKX74081.1 - 1e-05 25.5 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 EKX74081.1 - 3.9e-05 23.9 0.0 0.21 11.9 0.0 3.3 2 1 0 2 2 2 2 ABC transporter Sigma54_activ_2 PF14532.1 EKX74081.1 - 4.8e-05 23.4 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 EKX74081.1 - 5.1e-05 22.9 0.0 0.31 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 EKX74081.1 - 5.4e-05 22.4 0.2 2 7.4 0.0 3.4 2 1 1 3 3 3 1 KaiC ResIII PF04851.10 EKX74081.1 - 7.1e-05 22.7 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EKX74081.1 - 0.00012 21.6 0.0 0.01 15.3 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EKX74081.1 - 0.00025 19.9 0.1 0.61 8.9 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain Parvo_NS1 PF01057.12 EKX74081.1 - 0.00026 19.9 0.0 0.44 9.3 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EKX74081.1 - 0.0005 19.5 0.0 0.93 8.9 0.0 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.8 EKX74081.1 - 0.0011 17.9 0.0 0.34 9.8 0.0 2.6 3 0 0 3 3 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 EKX74081.1 - 0.0014 17.8 0.2 1.2 8.3 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Vps4_C PF09336.5 EKX74081.1 - 0.0022 17.8 0.4 0.021 14.6 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 EKX74081.1 - 0.0025 17.4 0.0 2.1 7.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 EKX74081.1 - 0.0049 16.5 0.0 2.2 7.8 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein SKI PF01202.17 EKX74081.1 - 0.006 16.4 0.1 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.10 EKX74081.1 - 0.0061 16.2 0.1 2.5 7.7 0.0 3.4 3 1 0 3 3 3 1 NTPase DUF2075 PF09848.4 EKX74081.1 - 0.0074 15.2 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EKX74081.1 - 0.018 14.6 0.0 6.6 6.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain UPF0079 PF02367.12 EKX74081.1 - 0.023 14.3 0.1 5.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EKX74081.1 - 0.031 13.7 0.6 6.8 6.0 0.0 3.2 2 1 0 3 3 3 0 AAA-like domain AAA_23 PF13476.1 EKX74081.1 - 0.041 14.1 0.0 7.5 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 EKX74081.1 - 0.045 13.6 0.0 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family DEAD PF00270.24 EKX74081.1 - 0.063 12.7 0.0 21 4.5 0.0 3.2 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_29 PF13555.1 EKX74081.1 - 0.064 12.8 0.0 5.3 6.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.1 EKX74081.1 - 0.07 12.6 0.0 9.9 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain UFD1 PF03152.9 EKX74081.1 - 0.071 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 SRPRB PF09439.5 EKX74081.1 - 0.074 12.2 0.0 29 3.8 0.0 3.5 3 1 0 3 3 3 0 Signal recognition particle receptor beta subunit Zot PF05707.7 EKX74081.1 - 0.081 12.3 0.2 5.1 6.5 0.1 3.0 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) KTI12 PF08433.5 EKX74081.1 - 0.16 11.1 0.0 8.4 5.5 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IFT57 PF10498.4 EKX74083.1 - 0.0044 15.8 2.1 0.0074 15.0 0.2 1.9 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 LSM PF01423.17 EKX74084.1 - 1.2e-10 40.8 0.0 2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EKX74084.1 - 0.025 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF1014 PF06244.7 EKX74084.1 - 0.13 12.4 0.7 0.22 11.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) Bromodomain PF00439.20 EKX74085.1 - 0.0051 16.7 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 Bromodomain Choline_kinase PF01633.15 EKX74086.1 - 8.4e-52 175.8 0.7 6.5e-51 172.9 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EKX74086.1 - 9.6e-14 51.6 0.0 3e-13 50.0 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EKX74086.1 - 0.064 12.3 0.1 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.20 EKX74087.1 - 1.2e-61 208.1 0.0 1.4e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX74087.1 - 4e-40 137.5 0.0 5.5e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKX74087.1 - 0.00072 18.6 0.0 0.00098 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKX74087.1 - 0.065 12.2 0.2 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.17 EKX74089.1 - 8.2e-81 265.6 0.7 2e-20 72.1 0.1 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX74089.1 - 5.5e-56 186.4 0.0 2.5e-14 53.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX74089.1 - 1.3e-41 140.2 0.0 2.8e-09 36.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EKX74089.1 - 9.9e-27 92.4 0.7 2.8e-26 90.9 0.2 2.0 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EKX74089.1 - 4.6e-06 26.3 0.5 0.39 10.5 0.0 4.2 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EKX74089.1 - 6.6e-06 25.9 0.2 0.4 10.5 0.0 3.8 4 0 0 4 4 4 2 RNA binding motif Limkain-b1 PF11608.3 EKX74089.1 - 4e-05 23.3 0.0 0.26 11.0 0.0 3.8 4 0 0 4 4 4 2 Limkain b1 RRS1 PF04939.7 EKX74090.1 - 3.4e-31 107.9 7.5 5.9e-31 107.1 5.2 1.4 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) CBM_11 PF03425.8 EKX74090.1 - 0.036 13.7 0.3 0.09 12.4 0.1 1.6 2 0 0 2 2 2 0 Carbohydrate binding domain (family 11) GrpE PF01025.14 EKX74091.1 - 1.7e-41 141.5 17.0 1.2e-40 138.7 11.7 1.9 1 1 0 1 1 1 1 GrpE Mnd1 PF03962.10 EKX74091.1 - 0.0018 17.9 6.2 0.003 17.2 4.3 1.3 1 0 0 1 1 1 1 Mnd1 family APG6 PF04111.7 EKX74091.1 - 0.046 12.7 9.7 0.063 12.3 6.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ORF6C PF10552.4 EKX74091.1 - 0.052 13.2 14.2 0.049 13.3 1.9 3.2 3 0 0 3 3 3 0 ORF6C domain V_ATPase_I PF01496.14 EKX74091.1 - 0.068 11.0 6.4 0.077 10.8 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bap31 PF05529.7 EKX74091.1 - 0.48 9.8 4.8 0.72 9.2 3.3 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF2730 PF10805.3 EKX74091.1 - 0.56 9.9 9.5 1.1 9.0 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF1664 PF07889.7 EKX74091.1 - 0.71 9.6 8.7 0.38 10.5 4.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 EKX74091.1 - 0.71 9.4 14.4 1 8.9 10.0 1.1 1 0 0 1 1 1 0 IncA protein DUF1644 PF07800.7 EKX74091.1 - 2.5 7.9 6.6 16 5.3 4.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) TPD52 PF04201.10 EKX74091.1 - 3.6 7.3 12.4 4.3 7.0 8.1 1.5 2 0 0 2 2 2 0 Tumour protein D52 family DUF3498 PF12004.3 EKX74091.1 - 8 5.4 11.4 12 4.8 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) LSM PF01423.17 EKX74093.1 - 9e-14 50.7 2.1 1.2e-13 50.4 1.4 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.12 EKX74093.1 - 0.007 16.0 0.5 0.013 15.1 0.1 1.6 2 0 0 2 2 2 1 Biotin protein ligase C terminal domain Gemin7 PF11095.3 EKX74093.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Tim44 PF04280.10 EKX74094.1 - 5.5e-27 94.5 0.0 1.3e-26 93.3 0.0 1.7 2 0 0 2 2 2 1 Tim44-like domain DUF773 PF05600.7 EKX74094.1 - 0.81 8.3 7.2 5 5.7 5.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF773) Tim17 PF02466.14 EKX74095.1 - 7.5e-30 103.5 3.5 7.5e-30 103.5 2.4 1.3 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family MMS19_N PF14500.1 EKX74096.1 - 2.7e-27 95.6 5.0 6.4e-27 94.4 3.4 1.7 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II PhyH PF05721.8 EKX74097.1 - 0.0091 16.0 0.0 0.03 14.3 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FAINT PF04385.10 EKX74098.1 - 3.3e-13 49.2 9.1 0.0064 16.3 0.2 4.6 4 0 0 4 4 4 4 Domain of unknown function, DUF529 EMA PF02488.10 EKX74098.1 - 9.1e-06 25.3 11.1 0.017 14.6 0.4 3.5 2 1 1 3 3 3 3 Merozoite Antigen Lipocalin PF00061.18 EKX74099.1 - 0.12 12.4 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Transket_pyr PF02779.19 EKX74102.1 - 1.2e-40 138.8 0.0 1.7e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EKX74102.1 - 3.2e-36 123.9 0.1 5.4e-36 123.2 0.1 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain tRNA-synt_2b PF00587.20 EKX74103.1 - 3.2e-43 147.2 0.0 9.2e-43 145.8 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EKX74103.1 - 3e-19 68.7 0.1 7.5e-19 67.4 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EKX74103.1 - 7.5e-09 35.3 0.0 1.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_His PF13393.1 EKX74103.1 - 0.12 11.3 0.0 0.31 10.0 0.0 1.6 2 0 0 2 2 2 0 Histidyl-tRNA synthetase ThiF PF00899.16 EKX74104.1 - 1.2e-22 80.2 0.0 1.9e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.14 EKX74104.1 - 0.00072 18.7 0.0 0.008 15.3 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EKX74104.1 - 0.004 17.2 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EKX74104.1 - 0.077 13.4 0.8 0.55 10.6 0.6 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EKX74104.1 - 0.17 11.8 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain PLU-1 PF08429.6 EKX74105.1 - 5.9e-28 97.7 3.1 1.6e-25 89.7 1.2 2.3 2 0 0 2 2 2 2 PLU-1-like protein EGF_3 PF12947.2 EKX74106.1 - 4.4e-05 23.3 34.5 7e-05 22.6 4.0 4.0 4 0 0 4 4 4 3 EGF domain FXa_inhibition PF14670.1 EKX74106.1 - 0.002 18.1 5.5 0.002 18.1 3.8 4.5 4 1 1 5 5 5 1 Coagulation Factor Xa inhibitory site hEGF PF12661.2 EKX74106.1 - 0.022 14.8 12.3 0.69 10.1 0.3 4.3 3 0 0 3 3 3 0 Human growth factor-like EGF cEGF PF12662.2 EKX74106.1 - 1.3 8.7 32.8 0.32 10.6 0.3 5.0 6 0 0 6 6 6 0 Complement Clr-like EGF-like EGF_2 PF07974.8 EKX74106.1 - 3.6 7.8 26.4 0.96 9.6 3.3 4.6 4 1 0 4 4 4 0 EGF-like domain EGF PF00008.22 EKX74106.1 - 8.8 6.4 37.4 0.15 12.0 5.8 4.9 4 2 1 5 5 5 0 EGF-like domain ABC_tran PF00005.22 EKX74107.1 - 8.3e-39 133.0 6.6 9.9e-19 68.0 0.0 4.5 3 2 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EKX74107.1 - 2.7e-22 80.0 29.9 2.8e-13 50.4 6.2 3.9 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 EKX74107.1 - 3.3e-09 36.3 8.7 6.4e-07 28.8 0.4 3.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EKX74107.1 - 1.6e-07 30.7 0.1 0.006 16.0 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EKX74107.1 - 2.5e-07 30.0 0.4 0.0099 15.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKX74107.1 - 9.5e-07 28.9 0.0 0.013 15.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EKX74107.1 - 1e-06 28.8 2.1 1.1 9.4 0.0 4.1 4 0 0 4 4 3 3 AAA domain AAA_18 PF13238.1 EKX74107.1 - 2.4e-06 27.8 3.1 0.0063 16.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 EKX74107.1 - 3.5e-06 26.7 0.0 0.032 13.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain Miro PF08477.8 EKX74107.1 - 3.9e-06 27.3 0.6 0.016 15.7 0.1 3.4 3 0 0 3 3 2 2 Miro-like protein AAA_23 PF13476.1 EKX74107.1 - 4.7e-06 27.0 0.5 4.7e-06 27.0 0.3 4.0 3 1 1 4 4 3 1 AAA domain AAA_17 PF13207.1 EKX74107.1 - 2.6e-05 25.0 0.1 0.21 12.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain NB-ARC PF00931.17 EKX74107.1 - 3.6e-05 22.7 0.0 0.17 10.7 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain MMR_HSR1 PF01926.18 EKX74107.1 - 4.1e-05 23.5 3.7 0.036 14.0 1.0 3.2 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 EKX74107.1 - 0.0001 21.5 39.9 0.026 13.5 0.1 5.8 2 2 0 5 5 4 4 AAA ATPase domain AAA_10 PF12846.2 EKX74107.1 - 0.00064 19.2 2.0 4.8 6.5 1.3 3.5 2 1 0 2 2 2 1 AAA-like domain MobB PF03205.9 EKX74107.1 - 0.00067 19.3 1.6 0.065 12.9 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EKX74107.1 - 0.00086 19.4 0.4 1.6 8.9 0.0 3.2 3 0 0 3 3 2 2 RNA helicase AAA PF00004.24 EKX74107.1 - 0.0021 18.2 0.0 3.5 7.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EKX74107.1 - 0.0022 17.9 0.0 0.21 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EKX74107.1 - 0.0031 17.1 2.0 0.091 12.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 EKX74107.1 - 0.0033 17.1 0.2 1 9.0 0.0 2.6 2 0 0 2 2 2 1 NTPase SbcCD_C PF13558.1 EKX74107.1 - 0.0055 16.5 0.2 0.21 11.5 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit FeoB_N PF02421.13 EKX74107.1 - 0.0098 15.1 0.3 2.3 7.4 0.1 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_33 PF13671.1 EKX74107.1 - 0.013 15.3 0.0 3.9 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EKX74107.1 - 0.016 14.9 0.2 12 5.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 EKX74107.1 - 0.027 13.2 0.0 1.4 7.5 0.0 2.4 2 0 0 2 2 2 0 ArgK protein ABC_tran_2 PF12848.2 EKX74107.1 - 0.055 13.3 0.1 0.055 13.3 0.1 3.0 2 1 1 3 3 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 EKX74107.1 - 0.055 12.9 0.1 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.1 EKX74107.1 - 0.07 12.5 0.0 8.1 5.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain EAP30 PF04157.11 EKX74109.1 - 3.5e-14 52.5 0.2 8.5e-14 51.2 0.2 1.6 1 1 0 1 1 1 1 EAP30/Vps36 family DUF759 PF05537.6 EKX74109.1 - 0.0078 15.0 0.3 0.01 14.6 0.2 1.2 1 0 0 1 1 1 1 Borrelia burgdorferi protein of unknown function (DUF759) RRM_1 PF00076.17 EKX74110.1 - 5.8e-12 45.0 0.0 8.6e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX74110.1 - 1.7e-11 43.9 0.0 2.5e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX74110.1 - 3.8e-09 36.2 0.0 6.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CXCXC PF03128.9 EKX74110.1 - 6.6 7.1 7.7 1.3 9.2 2.4 2.0 2 0 0 2 2 2 0 CXCXC repeat ADK PF00406.17 EKX74111.1 - 3.1e-29 101.7 0.0 4.1e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 EKX74111.1 - 1.5e-09 38.7 0.0 3.7e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKX74111.1 - 3e-08 34.0 0.0 8e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EKX74111.1 - 1e-06 28.6 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EKX74111.1 - 2.2e-05 24.6 0.0 3.9e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ADK_lid PF05191.9 EKX74111.1 - 7e-05 22.4 0.8 0.00013 21.5 0.5 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_22 PF13401.1 EKX74111.1 - 0.00027 21.0 0.0 0.00043 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EKX74111.1 - 0.00077 19.3 0.1 0.0024 17.7 0.0 1.8 2 0 0 2 2 2 1 Shikimate kinase Rad17 PF03215.10 EKX74111.1 - 0.0036 16.0 0.0 0.0053 15.5 0.0 1.5 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EKX74111.1 - 0.0048 15.9 0.0 0.0091 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EKX74111.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EKX74111.1 - 0.019 14.5 0.0 0.042 13.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EKX74111.1 - 0.027 13.5 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 EKX74111.1 - 0.032 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EKX74111.1 - 0.034 13.5 0.0 0.096 12.0 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 EKX74111.1 - 0.039 13.1 0.0 0.07 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EKX74111.1 - 0.039 14.2 0.0 0.071 13.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 EKX74111.1 - 0.047 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EKX74111.1 - 0.069 12.5 0.1 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain Ribosomal_L29 PF00831.18 EKX74112.1 - 6.3e-18 64.2 1.7 6.3e-18 64.2 1.1 2.5 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EKX74112.1 - 0.005 17.0 3.7 0.0064 16.7 2.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PP_kinase_C PF13090.1 EKX74112.1 - 0.017 13.7 0.6 0.019 13.5 0.4 1.1 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain TMP_2 PF06791.8 EKX74112.1 - 0.024 14.2 1.1 0.029 13.9 0.8 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein Muted PF14942.1 EKX74112.1 - 0.085 12.7 10.0 0.19 11.6 6.9 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF2152 PF10222.4 EKX74112.1 - 0.2 9.8 5.5 0.22 9.6 3.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) Snapin_Pallidin PF14712.1 EKX74112.1 - 0.25 11.6 10.1 0.072 13.4 2.0 2.2 1 1 0 2 2 2 0 Snapin/Pallidin Mgr1 PF08602.5 EKX74112.1 - 0.59 9.0 5.7 0.7 8.8 3.9 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF4407 PF14362.1 EKX74112.1 - 1.1 8.1 7.3 2.2 7.1 4.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4404 PF14357.1 EKX74112.1 - 2.7 8.4 5.3 2.1 8.8 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF2413 PF10310.4 EKX74112.1 - 3.4 6.3 9.1 5 5.8 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) MerR-DNA-bind PF09278.6 EKX74112.1 - 7.7 6.9 6.9 8.3 6.8 1.0 2.6 2 1 0 2 2 2 0 MerR, DNA binding DUF2637 PF10935.3 EKX74113.1 - 0.33 10.8 12.1 0.13 12.1 2.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2637) PGK PF00162.14 EKX74114.1 - 2.5e-13 49.3 2.2 3.2e-13 49.0 1.5 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase FAD_binding_4 PF01565.18 EKX74116.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAINT PF04385.10 EKX74117.1 - 8.7e-08 31.9 21.6 0.00026 20.7 0.2 6.0 4 2 1 5 5 5 3 Domain of unknown function, DUF529 Tropomyosin PF00261.15 EKX74119.1 - 0.039 13.0 0.1 0.095 11.7 0.1 1.6 1 0 0 1 1 1 0 Tropomyosin PGK PF00162.14 EKX74121.1 - 5.7e-149 495.8 0.0 6.4e-149 495.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase OGG_N PF07934.7 EKX74123.1 - 8.4e-21 74.1 0.1 1.3e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EKX74123.1 - 2.8e-15 56.5 0.0 4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EKX74123.1 - 1.2e-06 27.9 0.0 2.9e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF2400 PF09674.5 EKX74123.1 - 0.0062 16.2 0.0 0.043 13.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2400) AP2 PF00847.15 EKX74124.1 - 2.8e-06 27.3 3.4 5.5e-06 26.4 2.4 1.5 1 0 0 1 1 1 1 AP2 domain EFhand_Ca_insen PF08726.5 EKX74124.1 - 0.015 15.2 0.0 0.078 12.9 0.0 2.1 2 0 0 2 2 2 0 Ca2+ insensitive EF hand DLL_N PF12413.3 EKX74124.1 - 6.5 7.8 9.3 0.94 10.5 3.4 1.8 2 0 0 2 2 2 0 Homeobox protein distal-less-like N terminal ClpS PF02617.12 EKX74125.1 - 6e-19 67.5 0.1 9.7e-19 66.8 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS GATase_7 PF13537.1 EKX74125.1 - 0.068 12.9 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferase domain Peptidase_S26 PF10502.4 EKX74126.1 - 7.9e-06 25.4 0.0 3.1e-05 23.4 0.0 1.8 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 EKX74126.1 - 0.021 14.4 0.1 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase S24-like CHD5 PF04420.9 EKX74127.1 - 0.012 15.2 3.1 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 CHD5-like protein PspB PF06667.7 EKX74127.1 - 0.013 15.4 0.6 0.031 14.2 0.4 1.6 1 0 0 1 1 1 0 Phage shock protein B DUF1664 PF07889.7 EKX74127.1 - 0.05 13.3 0.3 6.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EKX74127.1 - 0.12 12.6 3.1 0.72 10.1 0.6 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GP41 PF00517.12 EKX74127.1 - 0.21 11.1 4.9 0.94 9.0 0.6 2.3 2 0 0 2 2 2 0 Retroviral envelope protein DASH_Duo1 PF08651.5 EKX74127.1 - 0.35 10.4 4.1 11 5.6 0.6 2.4 2 0 0 2 2 2 0 DASH complex subunit Duo1 SlyX PF04102.7 EKX74127.1 - 0.47 10.8 5.4 0.19 12.1 0.3 2.6 3 0 0 3 3 3 0 SlyX DASH_Dad4 PF08650.5 EKX74127.1 - 0.92 9.4 4.3 5.6 6.9 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad4 DUF4200 PF13863.1 EKX74127.1 - 2.8 7.8 5.7 4.2 7.3 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) FlaC_arch PF05377.6 EKX74127.1 - 3.8 7.4 5.9 8.2 6.4 0.8 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FAINT PF04385.10 EKX74128.1 - 5.7e-09 35.6 0.0 0.00024 20.9 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function, DUF529 zf-C3HC4_3 PF13920.1 EKX74129.1 - 2.1e-10 40.1 10.0 5.4e-10 38.7 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DNA_binding_2 PF13724.1 EKX74130.1 - 0.07 13.2 0.8 0.39 10.9 0.0 2.1 2 0 0 2 2 2 0 DNA-binding domain FAINT PF04385.10 EKX74132.1 - 1.4e-18 66.4 0.1 5.8e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.10 EKX74133.1 - 1.3e-24 85.8 17.9 5.4e-07 29.3 0.4 6.6 6 1 0 6 6 6 5 Domain of unknown function, DUF529 Cu_bind_like PF02298.12 EKX74133.1 - 0.052 13.3 0.4 7.4 6.4 0.0 3.4 3 0 0 3 3 3 0 Plastocyanin-like domain FAINT PF04385.10 EKX74134.1 - 1e-08 34.8 0.7 0.00059 19.6 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function, DUF529 NAPRTase PF04095.11 EKX74134.1 - 0.087 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Fimbrial_PilY2 PF14481.1 EKX74134.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 Abhydrolase_5 PF12695.2 EKX74135.1 - 1.9e-13 50.3 0.0 8.8e-13 48.2 0.0 2.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKX74135.1 - 2.1e-13 50.6 0.0 4.5e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX74135.1 - 1.1e-09 37.9 0.4 4.1e-08 32.9 0.1 3.1 3 0 0 3 3 3 1 Putative lysophospholipase FAINT PF04385.10 EKX74135.1 - 2.2e-09 37.0 6.2 0.07 12.9 0.0 5.3 5 0 0 5 5 5 3 Domain of unknown function, DUF529 Abhydrolase_1 PF00561.15 EKX74135.1 - 0.00066 19.3 0.0 0.017 14.6 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EKX74135.1 - 0.0019 17.7 0.1 0.004 16.6 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EKX74135.1 - 0.0084 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_4 PF08386.5 EKX74135.1 - 0.0095 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein DUF676 PF05057.9 EKX74135.1 - 0.01 15.1 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 EKX74135.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EKX74135.1 - 0.06 12.9 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) DUF900 PF05990.7 EKX74135.1 - 0.098 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) FAINT PF04385.10 EKX74136.1 - 4e-17 61.8 20.8 1.8e-07 30.8 1.6 4.4 4 0 0 4 4 4 3 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.2 EKX74136.1 - 6.1e-12 45.9 0.0 1.4e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKX74136.1 - 1.1e-08 34.8 0.0 3.5e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX74136.1 - 7.8e-06 25.6 0.0 2.2e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase EMA PF02488.10 EKX74136.1 - 9.9e-06 25.2 21.4 0.0014 18.1 8.2 2.3 1 1 1 2 2 2 2 Merozoite Antigen Abhydrolase_3 PF07859.8 EKX74136.1 - 0.00083 18.9 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EKX74136.1 - 0.0022 17.5 0.0 0.0086 15.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF456 PF04306.8 EKX74137.1 - 0.01 15.9 0.9 0.01 15.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Romo1 PF10247.4 EKX74137.1 - 0.011 15.9 0.1 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF4310 PF14187.1 EKX74137.1 - 0.02 14.4 0.4 0.021 14.3 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) Mid2 PF04478.7 EKX74137.1 - 0.061 12.7 0.2 0.062 12.7 0.1 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor PetG PF02529.10 EKX74137.1 - 3.8 7.1 5.3 4.5 6.8 3.1 1.6 1 1 0 1 1 1 0 Cytochrome B6-F complex subunit 5 RNA_pol PF00940.14 EKX74139.1 - 1.5e-134 448.5 0.0 2.3e-134 447.9 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EKX74139.1 - 3.8e-19 69.0 0.0 2.8e-18 66.2 0.0 2.2 1 1 0 1 1 1 1 DNA-directed RNA polymerase N-terminal RNA_pol_Rpb4 PF03874.11 EKX74140.1 - 0.043 13.8 0.7 0.043 13.8 0.5 2.8 2 1 1 3 3 3 0 RNA polymerase Rpb4 ubiquitin PF00240.18 EKX74141.1 - 2.9e-06 26.6 0.0 4.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family SPC25 PF06703.6 EKX74141.1 - 0.031 13.8 1.6 0.054 13.0 1.1 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Rad60-SLD PF11976.3 EKX74141.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EKX74141.1 - 0.11 12.3 0.1 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rep_fac_C PF08542.6 EKX74142.1 - 0.0059 16.5 0.0 0.0078 16.1 0.0 1.1 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EKX74144.1 - 6.4e-16 58.4 1.0 1.3e-15 57.3 0.2 1.9 2 1 0 2 2 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EKX74144.1 - 9.2e-13 48.5 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EKX74144.1 - 1.5e-09 37.0 0.1 2.2e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 EKX74144.1 - 5.5e-08 32.6 0.0 8.9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKX74144.1 - 1.1e-06 28.8 0.0 3.1e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EKX74144.1 - 3.2e-06 26.8 0.0 4.2e-06 26.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EKX74144.1 - 1e-05 25.4 0.0 2.5e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKX74144.1 - 1.7e-05 24.4 0.0 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EKX74144.1 - 6.4e-05 22.6 0.0 0.00014 21.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EKX74144.1 - 6.5e-05 22.0 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus SNF2_N PF00176.18 EKX74144.1 - 0.00013 20.8 0.2 0.0042 15.9 0.0 2.1 1 1 1 2 2 2 1 SNF2 family N-terminal domain TIP49 PF06068.8 EKX74144.1 - 0.00024 19.9 0.2 0.014 14.0 0.0 2.4 2 1 0 3 3 3 1 TIP49 C-terminus DEAD PF00270.24 EKX74144.1 - 0.00024 20.6 0.1 0.26 10.7 0.0 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase AAA_16 PF13191.1 EKX74144.1 - 0.00039 20.4 0.0 0.00092 19.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EKX74144.1 - 0.00042 19.4 0.0 0.00059 18.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EKX74144.1 - 0.0008 18.6 0.6 0.014 14.6 0.0 2.3 1 1 0 2 2 2 1 PhoH-like protein AAA_17 PF13207.1 EKX74144.1 - 0.00084 20.1 0.0 0.0011 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 EKX74144.1 - 0.00096 18.7 0.1 0.0015 18.1 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit IstB_IS21 PF01695.12 EKX74144.1 - 0.001 18.4 0.0 0.037 13.4 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ResIII PF04851.10 EKX74144.1 - 0.0017 18.1 0.2 0.029 14.2 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EKX74144.1 - 0.0021 17.5 0.1 0.0059 16.0 0.1 1.9 2 1 0 2 2 1 1 AAA domain Zot PF05707.7 EKX74144.1 - 0.0042 16.5 0.1 0.047 13.1 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) KTI12 PF08433.5 EKX74144.1 - 0.0047 16.1 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Mg_chelatase PF01078.16 EKX74144.1 - 0.0058 15.8 0.1 0.074 12.1 0.0 2.3 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EKX74144.1 - 0.0086 15.5 0.2 0.41 10.0 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain TPR_6 PF13174.1 EKX74144.1 - 0.015 15.6 0.4 4.7 7.8 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat ArgK PF03308.11 EKX74144.1 - 0.023 13.4 0.1 0.88 8.2 0.0 2.0 1 1 1 2 2 2 0 ArgK protein AAA_18 PF13238.1 EKX74144.1 - 0.023 15.0 0.0 0.044 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain NYD-SP12_N PF15015.1 EKX74144.1 - 0.025 12.8 0.0 0.035 12.3 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal AAA_33 PF13671.1 EKX74144.1 - 0.032 14.1 0.1 0.053 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EKX74144.1 - 0.045 13.2 0.8 0.21 11.0 0.0 1.9 1 1 1 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 EKX74144.1 - 0.045 12.3 0.0 0.071 11.7 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain CobA_CobO_BtuR PF02572.10 EKX74144.1 - 0.07 12.7 0.5 1.4 8.5 0.1 2.2 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP RNA_helicase PF00910.17 EKX74144.1 - 0.072 13.2 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EKX74144.1 - 0.089 12.7 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain FAINT PF04385.10 EKX74146.1 - 1.1e-06 28.3 1.4 2e-06 27.5 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX74147.1 - 7.9e-25 86.5 0.0 5.4e-07 29.3 0.0 4.4 4 0 0 4 4 4 4 Domain of unknown function, DUF529 FAINT PF04385.10 EKX74149.1 - 5.1e-12 45.4 0.1 0.00014 21.6 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 ORF11CD3 PF10549.4 EKX74149.1 - 0.0052 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 ORF11CD3 domain FAINT PF04385.10 EKX74151.1 - 1.2e-17 63.5 16.7 5.5e-07 29.3 0.9 4.7 5 0 0 5 5 5 4 Domain of unknown function, DUF529 AAA_4 PF04326.9 EKX74153.1 - 0.044 13.9 0.0 9.5 6.3 0.0 2.6 2 1 0 2 2 2 0 Divergent AAA domain Ribosomal_S26e PF01283.14 EKX74154.1 - 8.1e-49 164.6 8.4 9e-49 164.4 5.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e SRP19 PF01922.12 EKX74154.1 - 0.031 14.8 0.2 0.071 13.6 0.2 1.8 1 1 0 1 1 1 0 SRP19 protein zf-ribbon_3 PF13248.1 EKX74154.1 - 0.079 12.1 0.1 0.079 12.1 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Eapp_C PF10238.4 EKX74155.1 - 4.8e-19 68.6 7.3 7.8e-19 67.9 5.0 1.3 1 1 0 1 1 1 1 E2F-associated phosphoprotein Yippee-Mis18 PF03226.9 EKX74155.1 - 0.65 10.0 6.0 1 9.4 4.2 1.3 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Pkinase PF00069.20 EKX74157.1 - 1.7e-77 260.1 0.0 2.4e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX74157.1 - 2.1e-41 141.6 0.0 3e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EKX74157.1 - 1.6e-26 89.5 11.7 6.7e-08 31.2 0.5 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EKX74157.1 - 9.2e-24 83.3 4.3 1.1e-11 44.6 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EKX74157.1 - 3.8e-21 73.4 13.6 1.5e-05 24.0 0.9 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EKX74157.1 - 1.2e-20 71.4 7.4 6.8e-05 22.4 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EKX74157.1 - 1.3e-18 66.3 10.5 1.1e-05 24.9 0.4 4.6 2 1 2 4 4 4 4 EF-hand domain pair Kinase-like PF14531.1 EKX74157.1 - 1.4e-07 30.7 0.0 2.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like SPARC_Ca_bdg PF10591.4 EKX74157.1 - 2.5e-07 30.7 0.6 0.054 13.5 0.0 3.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EKX74157.1 - 3.9e-07 29.7 3.9 0.0009 18.9 0.1 3.4 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand APH PF01636.18 EKX74157.1 - 7.1e-05 22.6 0.0 0.0086 15.8 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EKX74157.1 - 0.00025 20.1 0.0 0.00046 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EKX74157.1 - 0.0017 17.7 0.2 0.0054 16.0 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL VCBS PF13517.1 EKX74157.1 - 6.1 7.2 7.2 60 4.1 0.1 3.2 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella WD40 PF00400.27 EKX74158.1 - 0.00059 19.6 0.4 0.13 12.1 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF1344 PF07076.6 EKX74158.1 - 0.0053 16.3 0.0 0.035 13.6 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1344) WD40 PF00400.27 EKX74160.1 - 7.9e-09 35.0 0.7 3.5e-06 26.6 0.2 3.3 3 1 0 3 3 3 1 WD domain, G-beta repeat eIF2A PF08662.6 EKX74160.1 - 0.11 12.1 0.1 1.5 8.4 0.1 2.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Topo-VIb_trans PF09239.6 EKX74161.1 - 0.031 13.7 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Topoisomerase VI B subunit, transducer FAINT PF04385.10 EKX74163.1 - 2.7e-24 84.8 1.9 8.9e-07 28.6 0.0 5.4 5 0 0 5 5 5 5 Domain of unknown function, DUF529 Tfb2 PF03849.9 EKX74165.1 - 7.1e-48 163.0 7.2 5.6e-32 110.7 0.3 3.3 2 1 1 3 3 3 2 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EKX74165.1 - 5.7e-08 32.5 0.0 1.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIN PF02760.10 EKX74165.1 - 0.0083 15.5 1.0 0.021 14.2 0.7 1.7 1 0 0 1 1 1 1 HIN-200/IF120x domain AHH PF14412.1 EKX74165.1 - 0.021 14.7 1.6 0.056 13.4 0.0 2.4 2 1 1 3 3 3 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF3782 PF12644.2 EKX74165.1 - 0.23 11.2 2.6 0.4 10.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) PH PF00169.24 EKX74166.1 - 0.018 15.2 0.4 0.034 14.3 0.3 1.5 1 0 0 1 1 1 0 PH domain Synaptobrevin PF00957.16 EKX74167.1 - 2.1e-06 27.2 1.8 3.7e-06 26.4 1.3 1.5 1 0 0 1 1 1 1 Synaptobrevin I_LWEQ PF01608.12 EKX74167.1 - 0.044 13.7 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 I/LWEQ domain LSM PF01423.17 EKX74168.1 - 4.2e-13 48.6 0.0 4.8e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EKX74168.1 - 7.7e-05 22.5 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Pribosyltran_N PF13793.1 EKX74169.1 - 1.2e-39 134.6 0.0 1.2e-37 128.1 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EKX74169.1 - 3.6e-24 85.5 3.0 4.3e-24 85.2 1.4 1.5 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EKX74169.1 - 1.1e-10 41.2 0.6 5.5e-10 39.0 0.2 2.3 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EKX74169.1 - 0.00035 19.8 0.0 0.00056 19.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Rad10 PF03834.9 EKX74171.1 - 1.3e-21 76.0 0.4 3e-21 74.8 0.2 1.6 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EKX74171.1 - 6.4e-05 23.0 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EKX74171.1 - 0.0024 17.6 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif IncA PF04156.9 EKX74172.1 - 0.0057 16.2 5.0 0.007 15.9 3.4 1.1 1 0 0 1 1 1 1 IncA protein DUF4446 PF14584.1 EKX74172.1 - 0.098 12.4 4.9 1.1 9.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Surfac_D-trimer PF09006.6 EKX74172.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation PBP_sp32 PF07222.7 EKX74172.1 - 0.76 8.8 8.5 0.98 8.5 5.9 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SlyX PF04102.7 EKX74172.1 - 0.81 10.1 3.6 10 6.5 0.1 2.6 2 0 0 2 2 2 0 SlyX Fib_alpha PF08702.5 EKX74172.1 - 2.7 8.0 8.8 0.13 12.4 2.3 1.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family KLRAQ PF10205.4 EKX74172.1 - 3.1 7.8 10.0 3.2 7.8 2.5 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF3847 PF12958.2 EKX74172.1 - 4.7 7.0 8.3 2.3 8.0 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) GOLD_2 PF13897.1 EKX74172.1 - 5.9 7.1 7.4 34 4.6 0.0 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking ANAPC15 PF15243.1 EKX74172.1 - 8.7 6.4 18.0 0.28 11.2 6.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Vps53_N PF04100.7 EKX74173.1 - 3.9e-64 216.8 5.6 3.9e-64 216.8 3.9 2.2 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF342 PF03961.8 EKX74173.1 - 6.8 4.9 9.1 0.71 8.2 1.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF342) FlxA PF14282.1 EKX74173.1 - 7.5 6.5 10.0 0.7 9.8 2.0 2.7 3 0 0 3 3 3 0 FlxA-like protein O-ag_pol_Wzy PF14296.1 EKX74174.1 - 0.0024 16.5 3.2 0.0026 16.3 2.2 1.1 1 0 0 1 1 1 1 O-antigen polysaccharide polymerase Wzy DAD PF02109.11 EKX74174.1 - 0.015 15.3 1.2 0.02 14.9 0.8 1.2 1 0 0 1 1 1 0 DAD family DUF4173 PF13777.1 EKX74174.1 - 0.032 13.5 1.8 0.035 13.3 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) Erythrovirus_X PF06795.6 EKX74174.1 - 0.054 13.5 0.1 0.074 13.0 0.1 1.2 1 0 0 1 1 1 0 Erythrovirus X protein DUF4181 PF13789.1 EKX74174.1 - 0.064 13.1 1.7 0.091 12.6 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) Col_cuticle_N PF01484.12 EKX74174.1 - 0.079 12.6 2.8 1.6 8.5 0.1 2.4 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain YwiC PF14256.1 EKX74174.1 - 0.099 12.7 0.2 0.15 12.1 0.2 1.3 1 1 0 1 1 1 0 YwiC-like protein Jiraiya PF15038.1 EKX74174.1 - 0.74 9.2 4.8 0.19 11.1 1.2 1.6 1 1 1 2 2 2 0 Jiraiya tRNA-synt_2c PF01411.14 EKX74175.1 - 3.2e-192 639.6 0.0 4.4e-192 639.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EKX74175.1 - 7.9e-12 44.8 0.8 1.6e-11 43.8 0.6 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain NAAA-beta PF15508.1 EKX74175.1 - 0.25 11.7 0.9 9.9 6.5 0.0 3.2 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase WD40 PF00400.27 EKX74176.1 - 0.0012 18.6 0.1 0.096 12.6 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF814 PF05670.8 EKX74177.1 - 8.7e-21 73.6 0.1 2.2e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) FbpA PF05833.6 EKX74177.1 - 1e-07 30.8 0.2 1.5e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1662 PF07878.6 EKX74178.1 - 0.11 12.2 0.3 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1662) DUF948 PF06103.6 EKX74179.1 - 0.018 14.9 1.2 0.047 13.5 0.9 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YjcZ PF13990.1 EKX74179.1 - 0.17 10.9 7.5 0.29 10.2 5.2 1.3 1 0 0 1 1 1 0 YjcZ-like protein DUF724 PF05266.9 EKX74179.1 - 0.4 10.2 17.1 0.46 10.0 11.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) NIF PF03031.13 EKX74180.1 - 7.2e-32 110.2 0.3 1.2e-31 109.5 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DWNN PF08783.6 EKX74181.1 - 3.5e-14 52.4 0.0 1.1e-13 50.9 0.0 1.9 1 0 0 1 1 1 1 DWNN domain zf-C3HC4_3 PF13920.1 EKX74181.1 - 3.1 7.5 12.5 7 6.4 8.7 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PseudoU_synth_2 PF00849.17 EKX74182.1 - 7.8e-28 97.3 0.1 1.1e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase KNTase_C PF07827.6 EKX74182.1 - 0.034 13.8 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 KNTase C-terminal domain Tcf25 PF04910.9 EKX74183.1 - 1.7e-42 145.6 4.5 2.7e-42 145.0 3.1 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Actin PF00022.14 EKX74184.1 - 4.8e-48 163.5 0.0 5.8e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Actin Hydantoinase_A PF01968.13 EKX74184.1 - 0.15 11.1 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Ppx-GppA PF02541.11 EKX74184.1 - 0.17 11.0 0.1 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family MtN3_slv PF03083.11 EKX74185.1 - 3e-25 87.9 18.0 5.2e-13 48.6 1.6 3.0 2 1 1 3 3 3 2 Sugar efflux transporter for intercellular exchange LAB_N PF07578.6 EKX74185.1 - 0.049 13.5 0.7 0.049 13.5 0.5 2.8 2 1 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain DUF4231 PF14015.1 EKX74185.1 - 2.7 8.0 5.3 2 8.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) SNAPc_SNAP43 PF09808.4 EKX74186.1 - 1.6e-05 24.6 0.6 2.1e-05 24.3 0.4 1.1 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 ATP_bind_1 PF03029.12 EKX74187.1 - 3.2e-65 220.0 0.0 3.8e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EKX74187.1 - 0.0002 22.1 0.1 0.0011 19.8 0.0 2.2 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EKX74187.1 - 0.0025 17.9 0.0 0.0079 16.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EKX74187.1 - 0.004 17.1 0.0 0.011 15.6 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.9 EKX74187.1 - 0.011 15.5 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EKX74187.1 - 0.013 15.8 0.8 0.26 11.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EKX74187.1 - 0.018 14.4 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EKX74187.1 - 0.026 14.0 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EKX74187.1 - 0.028 14.7 0.0 0.32 11.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter ArgK PF03308.11 EKX74187.1 - 0.032 13.0 0.0 0.065 12.0 0.0 1.4 2 0 0 2 2 2 0 ArgK protein ADK PF00406.17 EKX74187.1 - 0.053 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Adenylate kinase AAA_33 PF13671.1 EKX74187.1 - 0.081 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain PTEN_C2 PF10409.4 EKX74188.1 - 0.036 13.7 0.1 0.073 12.7 0.0 1.7 1 1 1 2 2 2 0 C2 domain of PTEN tumour-suppressor protein ThiF PF00899.16 EKX74189.1 - 2.2e-36 124.6 0.1 3.6e-36 123.9 0.1 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EKX74189.1 - 7.3e-20 70.3 0.5 1.9e-19 69.0 0.4 1.7 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EKX74189.1 - 7.9e-08 32.6 0.0 1.8e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EKX74189.1 - 0.0081 16.2 0.2 0.023 14.7 0.1 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EKX74189.1 - 0.13 11.6 0.2 0.32 10.4 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DnaJ PF00226.26 EKX74190.1 - 0.0024 17.5 0.2 0.0092 15.6 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain SYF2 PF08231.7 EKX74190.1 - 0.0039 17.3 3.8 0.2 11.7 0.8 2.5 2 0 0 2 2 2 2 SYF2 splicing factor OB_NTP_bind PF07717.11 EKX74191.1 - 9e-24 83.5 0.1 2.1e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EKX74191.1 - 4.5e-23 81.1 0.0 9.1e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EKX74191.1 - 3.2e-11 42.9 0.0 7.6e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKX74191.1 - 7.6e-09 35.2 0.1 1.7e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKX74191.1 - 1.5e-06 28.3 0.2 4.8e-06 26.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain ResIII PF04851.10 EKX74191.1 - 4.9e-05 23.2 0.1 0.088 12.6 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EKX74191.1 - 0.0022 17.7 0.1 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.1 EKX74191.1 - 0.0038 16.8 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EKX74191.1 - 0.01 14.7 0.0 0.023 13.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EKX74191.1 - 0.02 14.1 0.1 0.048 12.8 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.17 EKX74191.1 - 0.032 13.6 0.6 0.14 11.5 0.4 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EKX74191.1 - 0.034 13.5 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EKX74191.1 - 0.04 13.0 0.0 0.077 12.1 0.0 1.4 1 0 0 1 1 1 0 KaiC UPF0079 PF02367.12 EKX74191.1 - 0.047 13.3 0.1 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 EKX74191.1 - 0.048 13.5 0.1 0.53 10.1 0.0 2.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKX74191.1 - 0.071 13.4 0.2 0.21 11.8 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_29 PF13555.1 EKX74191.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EKX74191.1 - 0.13 11.6 0.0 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.1 EKX74191.1 - 0.15 11.8 0.1 0.41 10.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EKX74191.1 - 0.15 11.6 0.3 0.45 10.1 0.1 1.9 2 0 0 2 2 2 0 NACHT domain Atg8 PF02991.11 EKX74193.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.4 1 1 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like DUF3519 PF12033.3 EKX74194.1 - 0.059 13.5 0.3 0.22 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) zf-C3HC4_3 PF13920.1 EKX74196.1 - 1.7e-12 46.7 5.1 3.9e-12 45.6 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKX74196.1 - 6.1e-06 26.1 8.7 6.1e-06 26.1 6.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKX74196.1 - 1.8e-05 24.3 7.2 1.8e-05 24.3 5.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKX74196.1 - 3.4e-05 23.4 7.1 3.4e-05 23.4 4.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EKX74196.1 - 5.9e-05 22.8 7.0 5.9e-05 22.8 4.9 2.2 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.1 EKX74196.1 - 0.0013 18.2 4.5 0.003 17.0 3.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EKX74196.1 - 0.02 14.5 3.2 0.12 12.0 2.3 2.4 1 1 0 1 1 1 0 RING-type zinc-finger Cut8_N PF14482.1 EKX74196.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Cut8 proteasome-binding domain Rad50_zn_hook PF04423.9 EKX74196.1 - 0.12 11.9 0.3 0.23 10.9 0.2 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif Ribosomal_L10 PF00466.15 EKX74197.1 - 1.8e-09 37.4 0.0 7.1e-09 35.4 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein L10 OS-D PF03392.8 EKX74197.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D tRNA-synt_1d PF00750.14 EKX74198.1 - 6.3e-47 160.1 1.5 8.5e-24 84.0 0.4 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EKX74198.1 - 3.8e-11 42.9 0.0 8.1e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1e PF01406.14 EKX74198.1 - 0.097 11.7 0.0 0.52 9.3 0.0 2.1 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain PhoU_div PF01865.11 EKX74200.1 - 0.011 14.9 0.0 0.028 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF47 YoqO PF14037.1 EKX74200.1 - 0.022 14.8 0.8 0.061 13.4 0.6 1.8 1 0 0 1 1 1 0 YoqO-like protein WD40 PF00400.27 EKX74201.1 - 2e-23 81.3 20.9 9.3e-09 34.8 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat UTP15_C PF09384.5 EKX74201.1 - 2.2e-18 66.3 0.2 3.4e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 UTP15 C terminal Utp13 PF08625.6 EKX74201.1 - 0.0025 17.4 0.4 0.015 14.9 0.3 2.0 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain Pkinase PF00069.20 EKX74202.1 - 1.6e-33 115.9 0.6 2.6e-33 115.2 0.4 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX74202.1 - 1.7e-11 43.6 0.1 2.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Bromodomain PF00439.20 EKX74203.1 - 1e-11 44.5 0.1 3.3e-11 42.9 0.1 1.9 1 0 0 1 1 1 1 Bromodomain WD40 PF00400.27 EKX74203.1 - 5.3e-07 29.2 13.1 0.013 15.3 0.9 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Prok-RING_1 PF14446.1 EKX74203.1 - 0.0087 15.7 3.8 0.032 13.9 2.7 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 EKX74203.1 - 0.22 11.5 4.5 0.68 10.0 0.9 3.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AAR2 PF05282.6 EKX74204.1 - 1.6e-73 247.7 1.6 2.2e-73 247.3 1.1 1.1 1 0 0 1 1 1 1 AAR2 protein RRM_1 PF00076.17 EKX74205.1 - 1.1e-21 76.2 0.7 3.2e-21 74.7 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX74205.1 - 4.7e-17 61.7 0.6 2.2e-16 59.5 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX74205.1 - 1e-12 47.7 0.4 3.2e-12 46.1 0.3 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SseB_C PF14581.1 EKX74205.1 - 0.00091 19.0 0.2 0.0093 15.8 0.0 2.1 2 0 0 2 2 2 1 SseB protein C-terminal domain FlgI PF02119.11 EKX74205.1 - 0.0074 14.9 1.9 0.012 14.2 0.6 1.8 1 1 1 2 2 2 1 Flagellar P-ring protein Limkain-b1 PF11608.3 EKX74205.1 - 0.027 14.2 0.1 0.083 12.6 0.0 1.9 1 1 0 1 1 1 0 Limkain b1 AAA_23 PF13476.1 EKX74205.1 - 0.95 9.7 13.1 1.3 9.3 9.1 1.3 1 0 0 1 1 1 0 AAA domain SPOUT_MTase PF02590.12 EKX74205.1 - 1.2 8.8 7.2 0.68 9.6 0.1 2.2 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase UPF0449 PF15136.1 EKX74205.1 - 3.6 7.8 7.5 2.2 8.5 1.4 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 WD40 PF00400.27 EKX74206.1 - 0.00067 19.4 4.7 3.6 7.6 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat NEP PF10167.4 EKX74207.1 - 0.014 15.1 1.1 0.023 14.3 0.8 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein DUF2363 PF10155.4 EKX74207.1 - 0.019 14.9 0.1 0.04 13.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) RVT_3 PF13456.1 EKX74207.1 - 0.076 12.8 0.0 0.26 11.0 0.0 1.9 1 1 1 2 2 2 0 Reverse transcriptase-like DUF1033 PF06279.6 EKX74207.1 - 0.17 11.6 2.0 0.25 11.1 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) DUF1441 PF07278.6 EKX74207.1 - 0.19 11.3 2.2 0.37 10.4 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1441) Cyclin_C PF02984.14 EKX74207.1 - 0.29 11.0 1.5 0.66 9.9 0.4 1.8 1 1 1 2 2 2 0 Cyclin, C-terminal domain SusD-like_3 PF14322.1 EKX74207.1 - 0.32 11.0 4.8 1.5 8.8 2.5 1.9 1 1 1 2 2 2 0 Starch-binding associating with outer membrane Myb_DNA-bind_6 PF13921.1 EKX74208.1 - 9.1e-10 38.5 0.4 9.3e-07 28.8 0.1 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKX74208.1 - 2.3e-06 27.5 4.6 0.0027 17.7 0.4 4.2 3 2 0 3 3 3 2 Myb-like DNA-binding domain Phage_terminase PF10668.4 EKX74208.1 - 0.005 16.5 6.7 0.18 11.5 0.8 3.3 3 0 0 3 3 3 2 Phage terminase small subunit Myb_DNA-bind_4 PF13837.1 EKX74208.1 - 0.0071 16.4 1.6 0.041 14.0 0.1 2.9 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain ABA_GPCR PF12430.3 EKX74208.1 - 0.1 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor RAP PF08373.5 EKX74209.1 - 1.6e-14 53.3 0.3 4.2e-14 52.0 0.2 1.8 1 0 0 1 1 1 1 RAP domain DUF559 PF04480.7 EKX74209.1 - 0.0011 18.5 0.0 0.0033 17.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF559) Utp13 PF08625.6 EKX74209.1 - 0.14 11.8 2.9 0.7 9.5 0.1 3.1 2 1 1 3 3 3 0 Utp13 specific WD40 associated domain Fer4_6 PF12837.2 EKX74209.1 - 3.8 7.5 6.8 3.3 7.7 2.9 2.3 1 1 1 2 2 2 0 4Fe-4S binding domain PRP21_like_P PF12230.3 EKX74210.1 - 5.3e-41 140.6 7.6 2.6e-40 138.3 5.3 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EKX74210.1 - 5.4e-34 115.6 0.9 2.4e-16 59.0 0.0 2.4 2 0 0 2 2 2 2 Surp module DUF1682 PF07946.9 EKX74210.1 - 0.0062 15.4 0.0 0.0062 15.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) Collagen PF01391.13 EKX74212.1 - 0.0022 17.5 9.1 0.0022 17.5 6.3 1.9 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) ABC_tran PF00005.22 EKX74214.1 - 1.1e-31 109.9 0.0 1.1e-17 64.6 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_23 PF13476.1 EKX74214.1 - 3.6e-06 27.4 2.8 0.029 14.6 0.2 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EKX74214.1 - 7.2e-06 25.4 0.9 0.15 11.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EKX74214.1 - 4.3e-05 23.6 0.6 0.0059 16.6 0.0 4.7 5 1 0 5 5 4 2 AAA domain AAA_16 PF13191.1 EKX74214.1 - 6e-05 23.1 0.2 0.1 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EKX74214.1 - 8.8e-05 21.7 0.5 0.048 12.8 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EKX74214.1 - 0.00014 21.3 0.0 0.06 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKX74214.1 - 0.00033 20.9 0.1 0.45 10.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EKX74214.1 - 0.00038 19.3 0.4 0.0037 16.0 0.1 2.1 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 EKX74214.1 - 0.00042 21.1 0.0 0.32 11.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EKX74214.1 - 0.0014 18.2 0.2 0.24 10.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EKX74214.1 - 0.0016 17.5 0.2 0.82 8.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.18 EKX74214.1 - 0.0019 18.0 0.4 0.54 10.0 0.0 2.8 3 0 0 3 3 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 EKX74214.1 - 0.002 17.6 0.3 0.47 9.8 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family SMC_N PF02463.14 EKX74214.1 - 0.0046 16.2 1.6 0.065 12.4 0.1 2.6 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EKX74214.1 - 0.0057 15.6 0.2 1.4 7.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EKX74214.1 - 0.0064 16.4 0.2 0.25 11.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EKX74214.1 - 0.012 16.1 0.7 3.7 8.0 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein DUF87 PF01935.12 EKX74214.1 - 0.016 15.0 6.3 0.13 12.0 0.1 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 Fer4_NifH PF00142.13 EKX74214.1 - 0.018 14.2 0.1 5 6.2 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Endothelin PF00322.12 EKX74214.1 - 0.028 13.6 0.2 0.071 12.3 0.1 1.7 1 0 0 1 1 1 0 Endothelin family NACHT PF05729.7 EKX74214.1 - 0.037 13.6 0.7 7.1 6.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 EKX74214.1 - 0.041 13.5 0.5 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EKX74214.1 - 0.043 13.4 0.6 2.6 7.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EKX74214.1 - 0.048 13.0 0.5 8.5 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EKX74214.1 - 0.066 13.0 0.1 6.8 6.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EKX74214.1 - 0.072 13.2 0.0 21 5.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EKX74214.1 - 0.15 10.6 0.2 8.4 4.8 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.8 EKX74214.1 - 0.16 10.8 0.1 1 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 EKX74214.1 - 0.25 11.1 1.3 25 4.7 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain GAS PF13851.1 EKX74215.1 - 0.013 14.7 16.2 0.021 14.0 11.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PSD2 PF07624.6 EKX74215.1 - 0.11 12.1 1.2 0.53 9.9 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1585) Occludin_ELL PF07303.8 EKX74215.1 - 6 7.6 11.8 1.6 9.5 5.4 2.2 2 1 0 2 2 2 0 Occludin homology domain Rad60-SLD PF11976.3 EKX74217.1 - 8.5e-22 76.6 0.0 1e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EKX74217.1 - 2e-09 36.7 0.1 2.4e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family DUF61 PF01886.11 EKX74217.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF61 CLP_protease PF00574.18 EKX74218.1 - 8.9e-62 207.9 0.1 1.1e-61 207.6 0.1 1.1 1 0 0 1 1 1 1 Clp protease Glyco_transf_20 PF00982.16 EKX74218.1 - 0.0093 14.4 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 GCC2_GCC3 PF07699.8 EKX74219.1 - 4.2e-38 128.6 130.9 6.4e-08 32.0 7.8 12.2 12 1 1 13 13 13 10 GCC2 and GCC3 GCC2_GCC3 PF07699.8 EKX74220.1 - 5.8e-41 137.8 135.8 5.9e-08 32.1 7.8 11.9 11 1 1 12 12 12 9 GCC2 and GCC3 CENP-F_leu_zip PF10473.4 EKX74220.1 - 0.017 14.9 1.8 0.031 14.1 1.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-6_N PF09177.6 EKX74220.1 - 0.054 13.9 0.6 0.17 12.3 0.4 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal GTP_EFTU PF00009.22 EKX74221.1 - 1.1e-49 168.3 1.0 1.9e-49 167.6 0.7 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EKX74221.1 - 3.4e-34 117.0 0.1 9.6e-34 115.5 0.1 1.8 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EKX74221.1 - 3e-20 71.8 0.0 7.3e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EKX74221.1 - 8.5e-08 32.2 1.7 2.2e-07 30.8 0.6 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EKX74221.1 - 3.3e-06 26.8 0.0 1e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EKX74221.1 - 7.5e-06 25.8 0.1 1.5e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EKX74221.1 - 1.4e-05 24.5 0.1 3.3e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EKX74221.1 - 0.0001 22.7 0.7 0.00032 21.1 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 EKX74221.1 - 0.00032 20.2 1.1 0.00032 20.2 0.7 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Cpn10 PF00166.16 EKX74221.1 - 0.054 13.4 0.1 0.16 11.9 0.1 1.8 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit Porin_3 PF01459.17 EKX74222.1 - 1.1e-26 93.8 0.2 1.4e-26 93.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin Peptidase_C39_2 PF13529.1 EKX74223.1 - 0.0071 16.7 0.0 0.0095 16.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase_C39 like family Patatin PF01734.17 EKX74224.1 - 1.9e-09 37.7 0.1 6.6e-09 35.9 0.0 1.9 2 1 0 2 2 2 1 Patatin-like phospholipase Phage_Coat_A PF05357.8 EKX74224.1 - 0.00015 21.2 1.4 0.00021 20.8 0.2 1.8 2 0 0 2 2 2 1 Phage Coat Protein A Myc_target_1 PF15179.1 EKX74224.1 - 0.036 13.6 0.7 0.061 12.9 0.5 1.3 1 0 0 1 1 1 0 Myc target protein 1 Aconitase PF00330.15 EKX74225.1 - 2.8e-135 451.4 0.0 3.4e-135 451.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EKX74225.1 - 2.9e-41 140.6 0.0 5.2e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L2_C PF03947.13 EKX74226.1 - 1.2e-40 138.2 0.7 1.2e-40 138.2 0.5 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EKX74226.1 - 3.2e-18 65.4 0.2 6.9e-18 64.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain RNase_PH PF01138.16 EKX74227.1 - 7.6e-17 61.8 0.0 9.3e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Yos1 PF08571.5 EKX74228.1 - 3.9e-08 33.2 0.1 1.8e-07 31.1 0.1 2.2 1 0 0 1 1 1 1 Yos1-like DUF2110 PF09883.4 EKX74228.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) tRNA-synt_1c PF00749.16 EKX74229.1 - 2e-100 335.4 0.1 3e-100 334.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EKX74229.1 - 5.1e-34 117.4 0.0 2.4e-33 115.2 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.20 EKX74229.1 - 2.6e-08 33.7 0.0 7.3e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKX74229.1 - 5.9e-05 23.4 0.1 0.00017 22.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EKX74229.1 - 8.8e-05 22.3 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Intein_splicing PF14890.1 EKX74229.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Intein splicing domain Ribonuc_P_40 PF08584.6 EKX74231.1 - 9.9e-05 21.4 0.4 0.00064 18.8 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit DUF1639 PF07797.9 EKX74231.1 - 0.014 14.7 0.0 0.033 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) EMA PF02488.10 EKX74232.1 - 5.6e-79 265.1 10.9 6.9e-79 264.8 7.5 1.0 1 0 0 1 1 1 1 Merozoite Antigen Peptidase_C97 PF05903.9 EKX74233.1 - 3.6e-31 107.9 0.2 6.9e-31 107.0 0.1 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EKX74233.1 - 0.063 13.2 0.1 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Lecithin retinol acyltransferase RRM_1 PF00076.17 EKX74234.1 - 2.8e-28 97.3 0.2 3.7e-14 52.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX74234.1 - 3.4e-19 68.5 0.0 2e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX74234.1 - 2.2e-13 49.8 0.1 4.8e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKX74234.1 - 0.006 16.4 0.3 1.7 8.5 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EKX74234.1 - 0.0083 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF655 PF04919.7 EKX74234.1 - 0.069 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF655) DRIM PF07539.7 EKX74235.1 - 0.034 13.5 0.4 0.077 12.4 0.0 1.8 2 1 0 2 2 2 0 Down-regulated in metastasis SCF PF02404.10 EKX74235.1 - 0.052 12.7 0.7 0.086 12.0 0.5 1.3 1 0 0 1 1 1 0 Stem cell factor Syntaxin PF00804.20 EKX74235.1 - 0.07 13.3 1.8 0.16 12.1 0.4 2.1 2 0 0 2 2 2 0 Syntaxin Nsp1_C PF05064.8 EKX74235.1 - 0.12 11.9 1.6 0.57 9.8 0.1 2.5 2 1 0 2 2 2 0 Nsp1-like C-terminal region FlaE PF07559.9 EKX74236.1 - 0.029 15.0 0.1 0.044 14.4 0.1 1.3 1 0 0 1 1 1 0 Flagellar basal body protein FlaE Mito_carr PF00153.22 EKX74237.1 - 3.6e-25 87.4 2.6 5.1e-11 42.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1g PF09334.6 EKX74239.1 - 1.6e-79 267.3 0.2 8e-77 258.5 0.1 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EKX74239.1 - 7.8e-21 73.7 1.7 2.4e-10 39.0 0.1 4.1 2 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EKX74239.1 - 7.6e-09 35.1 0.0 0.00012 21.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EKX74239.1 - 0.018 13.7 0.2 3.1 6.3 0.0 3.0 3 0 0 3 3 3 0 tRNA synthetases class I (K) DUF1253 PF06862.7 EKX74240.1 - 5.1e-135 450.2 0.5 7e-135 449.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Imm-NTF2 PF15655.1 EKX74240.1 - 0.087 13.2 0.0 0.53 10.7 0.0 2.2 2 0 0 2 2 2 0 NTF2 fold immunity protein DUF4638 PF15472.1 EKX74240.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) zf-RING_2 PF13639.1 EKX74241.1 - 7.3e-14 51.3 6.0 7.3e-14 51.3 4.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EKX74241.1 - 1.4e-10 41.0 4.0 1.4e-10 41.0 2.8 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EKX74241.1 - 1.5e-06 27.7 5.1 1.5e-06 27.7 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKX74241.1 - 2.7e-06 26.9 7.8 3.1e-05 23.5 1.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKX74241.1 - 2.9e-05 23.7 4.6 2.9e-05 23.7 3.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKX74241.1 - 5.3e-05 23.1 5.2 5.3e-05 23.1 3.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EKX74241.1 - 8.8e-05 22.4 1.3 8.8e-05 22.4 0.9 2.6 2 0 0 2 2 2 1 zinc-finger zf-Apc11 PF12861.2 EKX74241.1 - 0.001 18.8 3.6 0.0029 17.4 2.5 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EKX74241.1 - 0.0029 17.5 5.1 0.0029 17.5 3.6 2.6 2 1 0 2 2 2 1 FANCL C-terminal domain Rad50_zn_hook PF04423.9 EKX74241.1 - 0.015 14.7 0.9 0.069 12.6 0.0 2.5 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-CHY PF05495.7 EKX74241.1 - 0.25 11.5 6.5 0.34 11.0 0.1 2.3 2 0 0 2 2 2 0 CHY zinc finger Baculo_RING PF05883.6 EKX74241.1 - 0.38 10.5 2.8 0.29 10.9 0.5 1.9 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain Zn-ribbon_8 PF09723.5 EKX74241.1 - 0.57 10.1 9.6 0.15 11.9 0.5 3.0 3 0 0 3 3 3 0 Zinc ribbon domain Baculo_IE-1 PF05290.6 EKX74241.1 - 0.73 9.5 4.0 0.16 11.6 0.2 1.7 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zinc-ribbons_6 PF07191.7 EKX74241.1 - 6.2 6.6 8.4 19 5.1 0.3 3.2 3 1 0 3 3 3 0 zinc-ribbons zf-RING_4 PF14570.1 EKX74241.1 - 8.8 6.0 10.0 0.52 9.9 2.2 2.3 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Cyclin_N PF00134.18 EKX74243.1 - 1.6e-08 34.1 0.4 1.4e-07 31.1 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EKX74243.1 - 0.028 14.3 0.0 1.1 9.2 0.0 2.4 2 1 0 2 2 2 0 Cyclin, C-terminal domain TFIIB PF00382.14 EKX74243.1 - 0.04 13.7 0.5 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Transcription factor TFIIB repeat NARP1 PF12569.3 EKX74244.1 - 7.6e-38 130.5 16.3 1.2e-26 93.5 6.5 3.8 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 EKX74244.1 - 3.7e-19 67.0 8.0 4.1e-05 23.1 0.0 7.4 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 EKX74244.1 - 2.9e-17 62.0 7.5 0.0023 17.5 0.2 5.5 5 0 0 5 5 5 4 TPR repeat TPR_1 PF00515.23 EKX74244.1 - 2.6e-15 55.3 6.5 1.3e-06 27.7 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EKX74244.1 - 1.1e-10 41.9 0.0 0.0026 18.3 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EKX74244.1 - 3.2e-09 36.6 0.0 5.2 7.9 0.0 6.9 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKX74244.1 - 1e-08 34.9 1.9 0.23 11.4 0.0 5.9 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKX74244.1 - 3.7e-08 32.5 9.9 0.037 13.8 0.2 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.1 EKX74244.1 - 1.5e-06 27.5 0.0 0.095 11.7 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EKX74244.1 - 3.7e-06 27.0 0.2 2.4 8.7 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EKX74244.1 - 0.00012 21.6 0.1 0.63 9.9 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EKX74244.1 - 0.00022 21.0 0.0 0.38 10.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKX74244.1 - 0.0006 19.6 5.0 3.7 7.4 0.1 4.1 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 EKX74244.1 - 0.00091 19.2 0.0 14 6.1 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EKX74244.1 - 0.0013 18.9 0.0 53 4.2 0.0 5.6 4 2 1 5 5 5 0 Tetratricopeptide repeat Prp18 PF02840.10 EKX74245.1 - 2.6e-54 182.9 0.3 2.6e-54 182.9 0.2 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EKX74245.1 - 2e-08 33.3 2.8 2e-08 33.3 1.9 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Ldh_1_C PF02866.13 EKX74246.1 - 4.8e-31 107.8 0.0 8.5e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EKX74246.1 - 1.6e-29 102.5 1.4 1.8e-29 102.3 0.3 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 EKX74246.1 - 1.1e-06 28.0 0.1 3.3e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase DUF1168 PF06658.7 EKX74247.1 - 1.7e-28 98.9 15.0 2e-28 98.7 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF3987 PF13148.1 EKX74247.1 - 0.41 9.1 12.7 0.56 8.7 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Atg14 PF10186.4 EKX74247.1 - 0.92 8.3 6.5 0.89 8.4 4.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_S49_N PF08496.5 EKX74247.1 - 1.1 8.9 13.7 0.33 10.7 7.6 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3513 PF12026.3 EKX74247.1 - 4.2 6.8 9.5 6 6.3 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Malate_DH PF12434.3 EKX74247.1 - 8 6.2 7.5 26 4.6 2.0 2.3 2 0 0 2 2 2 0 Malate dehydrogenase enzyme NAD_binding_1 PF00175.16 EKX74248.1 - 6.2e-18 65.3 0.0 9.3e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EKX74248.1 - 0.00021 21.2 0.0 0.044 13.6 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EKX74248.1 - 0.0057 16.7 0.0 0.0099 15.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain RVT_1 PF00078.22 EKX74249.1 - 0.042 13.2 2.1 0.06 12.6 0.0 2.1 2 1 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) EGF PF00008.22 EKX74250.1 - 0.0033 17.3 42.3 0.033 14.1 6.5 5.0 4 1 0 4 4 4 3 EGF-like domain FXa_inhibition PF14670.1 EKX74250.1 - 0.025 14.6 7.5 0.025 14.6 5.2 4.4 3 1 1 4 4 4 0 Coagulation Factor Xa inhibitory site hEGF PF12661.2 EKX74250.1 - 1.3 9.2 25.0 0.17 12.0 1.4 4.7 4 1 0 4 4 4 0 Human growth factor-like EGF cEGF PF12662.2 EKX74250.1 - 2.1 8.0 12.5 3.2 7.4 0.1 4.0 3 0 0 3 3 3 0 Complement Clr-like EGF-like Acetyltransf_1 PF00583.19 EKX74251.1 - 1.6e-09 37.6 0.0 2.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKX74251.1 - 2.2e-09 37.3 0.0 4.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EKX74251.1 - 0.00012 21.9 0.0 0.00018 21.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKX74251.1 - 0.00075 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKX74251.1 - 0.0017 18.2 0.0 0.0031 17.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKX74251.1 - 0.002 17.8 0.0 0.0074 16.0 0.0 1.9 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EKX74251.1 - 0.037 14.1 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKX74251.1 - 0.066 13.3 0.0 0.069 13.3 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain HECT PF00632.20 EKX74252.1 - 1.1e-47 162.8 2.4 2.3e-47 161.7 0.2 2.6 2 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Ank_4 PF13637.1 EKX74252.1 - 2.3e-10 40.7 1.8 0.0036 17.7 0.0 4.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKX74252.1 - 9.3e-09 35.2 0.2 0.00012 22.2 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKX74252.1 - 6.5e-08 32.8 0.0 6.6e-07 29.5 0.0 2.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EKX74252.1 - 1.2e-07 31.1 0.0 0.0013 18.4 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EKX74252.1 - 0.00043 20.2 0.1 2.4 8.6 0.0 4.4 3 0 0 3 3 3 1 Ankyrin repeat UPF0086 PF01868.11 EKX74253.1 - 9.3e-21 73.2 0.0 1.5e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Myb_DNA-bind_6 PF13921.1 EKX74254.1 - 0.076 13.1 1.3 1.5 8.9 0.1 3.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain CDP-OH_P_transf PF01066.16 EKX74255.1 - 1.4e-18 66.9 1.9 4.5e-18 65.4 1.3 1.9 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.20 EKX74256.1 - 4.2e-32 111.3 0.0 7e-23 81.0 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKX74256.1 - 2.5e-16 59.5 0.0 2.5e-12 46.4 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase WBP-1 PF11669.3 EKX74256.1 - 0.0019 18.2 0.0 0.0079 16.2 0.0 2.1 1 0 0 1 1 1 1 WW domain-binding protein 1 KH_1 PF00013.24 EKX74257.1 - 1.1e-09 37.8 0.1 2e-07 30.5 0.0 2.5 2 0 0 2 2 2 1 KH domain zf-CCHC PF00098.18 EKX74257.1 - 8.4e-05 22.3 9.2 0.085 12.8 0.1 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EKX74257.1 - 0.00013 21.4 0.1 0.00031 20.3 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EKX74257.1 - 0.0011 18.6 3.2 0.22 11.2 0.5 2.5 1 1 1 2 2 2 2 Zinc knuckle DUF4206 PF13901.1 EKX74257.1 - 0.0057 16.2 0.6 0.0057 16.2 0.4 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4206) zf-CCHC_4 PF14392.1 EKX74257.1 - 0.022 14.4 7.6 0.76 9.4 0.1 2.7 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EKX74257.1 - 0.056 13.4 3.2 0.15 12.1 2.2 1.7 1 0 0 1 1 1 0 DnaJ central domain TORC_N PF12884.2 EKX74257.1 - 0.17 12.4 6.0 0.62 10.6 4.2 2.0 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus zf-CCHC_6 PF15288.1 EKX74257.1 - 0.61 9.7 7.2 0.77 9.4 0.0 2.6 2 0 0 2 2 2 0 Zinc knuckle SUV3_C PF12513.3 EKX74258.1 - 5e-13 48.2 0.3 1.2e-12 47.0 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EKX74258.1 - 4.7e-11 42.4 0.1 1.3e-10 41.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Acetyltransf_13 PF13880.1 EKX74260.1 - 0.1 12.3 0.1 15 5.4 0.0 2.6 3 0 0 3 3 3 0 ESCO1/2 acetyl-transferase BACK PF07707.10 EKX74260.1 - 0.51 10.1 4.7 0.14 12.0 0.5 2.1 2 0 0 2 2 2 0 BTB And C-terminal Kelch MFS_1 PF07690.11 EKX74261.1 - 1.6e-19 69.8 29.0 1.6e-19 69.8 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GATase PF00117.23 EKX74261.1 - 1.4e-10 40.9 0.0 1e-09 38.1 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EKX74261.1 - 0.003 17.0 0.1 0.054 12.9 0.1 2.7 2 1 0 2 2 2 1 Peptidase C26 GATase_3 PF07685.9 EKX74261.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF3007 PF11460.3 EKX74261.1 - 0.16 12.0 0.3 0.58 10.2 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Helicase_C PF00271.26 EKX74263.1 - 1e-07 31.7 0.0 3.4e-06 26.8 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain GUCT PF08152.7 EKX74263.1 - 0.004 17.1 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain RAP PF08373.5 EKX74265.1 - 0.0075 16.0 0.2 0.0075 16.0 0.1 2.7 3 0 0 3 3 3 1 RAP domain AAA PF00004.24 EKX74266.1 - 7.3e-84 278.5 0.0 2.3e-46 157.2 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EKX74266.1 - 8.9e-12 44.5 0.0 4.8e-05 22.5 0.0 2.8 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EKX74266.1 - 1.1e-11 45.6 0.0 0.00013 22.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EKX74266.1 - 6.7e-11 42.5 0.9 0.0015 18.5 0.0 4.0 2 2 0 4 4 4 2 AAA ATPase domain AAA_5 PF07728.9 EKX74266.1 - 1.5e-10 40.9 0.1 0.0017 18.1 0.0 3.9 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EKX74266.1 - 4.4e-09 36.5 1.0 0.0041 17.2 0.0 4.2 3 2 1 4 4 3 2 AAA domain TIP49 PF06068.8 EKX74266.1 - 4.8e-09 35.4 0.7 0.0014 17.4 0.0 2.9 3 0 0 3 3 3 2 TIP49 C-terminus RNA_helicase PF00910.17 EKX74266.1 - 7.3e-09 35.7 0.1 0.0032 17.6 0.0 3.8 3 1 1 4 4 3 2 RNA helicase IstB_IS21 PF01695.12 EKX74266.1 - 3.5e-08 33.0 0.0 0.0026 17.1 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EKX74266.1 - 3.7e-08 33.3 0.0 0.00028 20.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 EKX74266.1 - 5.4e-08 32.9 0.0 0.00078 19.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EKX74266.1 - 6e-08 33.0 0.0 0.02 15.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EKX74266.1 - 8.5e-08 31.5 0.0 0.0054 15.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.22 EKX74266.1 - 1e-07 32.3 0.2 0.024 14.9 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_33 PF13671.1 EKX74266.1 - 1.9e-07 31.0 0.0 0.0078 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EKX74266.1 - 6.4e-07 28.7 0.5 0.016 14.3 0.0 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EKX74266.1 - 8.4e-07 28.5 3.7 0.43 9.9 0.0 4.3 2 2 1 4 4 4 2 AAA domain AAA_28 PF13521.1 EKX74266.1 - 4e-06 26.8 0.0 0.14 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EKX74266.1 - 1.8e-05 24.5 2.4 0.16 11.6 0.0 3.9 3 2 1 4 4 3 2 Archaeal ATPase Parvo_NS1 PF01057.12 EKX74266.1 - 2.4e-05 23.3 0.1 0.2 10.5 0.0 2.8 3 0 0 3 3 3 2 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 EKX74266.1 - 2.5e-05 23.8 0.0 0.21 11.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EKX74266.1 - 2.6e-05 23.8 0.4 0.073 12.8 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain DUF815 PF05673.8 EKX74266.1 - 5.6e-05 22.2 0.0 0.28 10.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.7 EKX74266.1 - 6.4e-05 22.6 0.2 0.24 11.0 0.0 3.2 4 0 0 4 4 3 2 NACHT domain Sigma54_activat PF00158.21 EKX74266.1 - 6.6e-05 22.4 0.0 0.47 9.8 0.0 4.0 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_24 PF13479.1 EKX74266.1 - 0.00017 21.2 0.2 0.17 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EKX74266.1 - 0.00061 18.7 0.1 0.089 11.6 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain SKI PF01202.17 EKX74266.1 - 0.00089 19.1 0.5 2.4 8.0 0.0 3.2 4 0 0 4 4 3 1 Shikimate kinase T2SE PF00437.15 EKX74266.1 - 0.0013 17.6 0.1 2.6 6.8 0.0 2.9 3 0 0 3 3 3 2 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 EKX74266.1 - 0.0016 18.5 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_29 PF13555.1 EKX74266.1 - 0.0016 17.8 0.1 0.13 11.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 EKX74266.1 - 0.0017 17.9 0.0 0.0095 15.4 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 EKX74266.1 - 0.0023 17.6 0.0 0.35 10.5 0.0 3.1 2 1 0 2 2 2 1 NTPase CPT PF07931.7 EKX74266.1 - 0.0024 17.5 0.0 0.55 9.8 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Vps4_C PF09336.5 EKX74266.1 - 0.003 17.4 0.5 0.21 11.5 0.1 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain SMC_N PF02463.14 EKX74266.1 - 0.0046 16.2 0.1 1.1 8.4 0.0 3.3 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EKX74266.1 - 0.0056 17.0 4.2 1.3 9.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 EKX74266.1 - 0.0093 15.5 0.0 2.9 7.3 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.1 EKX74266.1 - 0.012 15.5 0.0 0.51 10.2 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_10 PF12846.2 EKX74266.1 - 0.014 14.8 0.2 6.1 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 EKX74266.1 - 0.014 15.0 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EKX74266.1 - 0.017 14.2 0.1 1.6 7.8 0.0 2.9 2 0 0 2 2 2 0 KaiC Bac_DnaA PF00308.13 EKX74266.1 - 0.036 13.7 0.0 0.7 9.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial dnaA protein MMR_HSR1 PF01926.18 EKX74266.1 - 0.037 13.9 0.1 8.8 6.3 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase KTI12 PF08433.5 EKX74266.1 - 0.057 12.6 1.6 3.4 6.7 0.0 2.7 3 0 0 3 3 3 0 Chromatin associated protein KTI12 CobU PF02283.11 EKX74266.1 - 0.068 12.5 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_21 PF13304.1 EKX74266.1 - 0.074 12.9 8.0 1.9 8.4 0.0 3.8 3 1 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 EKX74266.1 - 0.083 12.3 0.0 3.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EKX74266.1 - 0.24 10.9 0.0 20 4.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EKX74266.1 - 0.67 9.1 3.3 5 6.2 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein DDHD PF02862.12 EKX74267.1 - 4.7e-27 95.2 0.9 6.6e-27 94.7 0.1 1.6 2 0 0 2 2 2 1 DDHD domain Lipase_2 PF01674.13 EKX74267.1 - 0.018 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) GAT PF03127.9 EKX74267.1 - 0.03 14.3 0.1 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 GAT domain DUF676 PF05057.9 EKX74267.1 - 0.035 13.4 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Sod_Fe_C PF02777.13 EKX74268.1 - 6.5e-39 132.0 0.2 4.8e-37 126.0 0.1 2.2 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EKX74268.1 - 3.5e-30 104.0 2.1 4.4e-30 103.7 0.2 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain RAP PF08373.5 EKX74271.1 - 2.5e-14 52.7 0.1 3e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 RAP domain DnaJ PF00226.26 EKX74273.1 - 7.9e-21 73.5 0.6 2.1e-20 72.1 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 EKX74273.1 - 8.8e-10 38.7 1.3 2e-09 37.6 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) YfiO PF13525.1 EKX74273.1 - 0.0088 15.5 0.1 0.022 14.2 0.1 1.6 1 0 0 1 1 1 1 Outer membrane lipoprotein TPR_2 PF07719.12 EKX74273.1 - 0.014 15.2 0.0 0.046 13.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EKX74273.1 - 0.049 13.1 0.2 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Foie gras liver health family 1 Apc3 PF12895.2 EKX74273.1 - 0.051 13.7 1.4 0.24 11.5 0.4 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SPRY PF00622.23 EKX74274.1 - 0.044 13.8 0.2 0.33 11.0 0.1 2.2 1 1 0 1 1 1 0 SPRY domain CLPTM1 PF05602.7 EKX74275.1 - 8.9e-89 298.1 7.8 1.2e-88 297.7 5.4 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 EKX74275.1 - 2.5e-07 30.1 1.3 0.016 14.7 0.0 2.9 2 0 0 2 2 2 2 PQ loop repeat H_PPase PF03030.11 EKX74275.1 - 0.095 10.9 2.5 0.13 10.5 1.8 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DoxX_3 PF13781.1 EKX74275.1 - 0.5 10.7 3.4 2.8 8.3 0.4 2.6 2 0 0 2 2 2 0 DoxX-like family DUF161 PF02588.10 EKX74275.1 - 3.9 7.8 8.4 16 5.8 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized BCR, YitT family COG1284 Peptidase_M18 PF02127.10 EKX74276.1 - 1.5e-120 402.6 0.0 1.7e-120 402.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EKX74276.1 - 0.00052 18.8 0.0 0.05 12.3 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Syja_N PF02383.13 EKX74277.1 - 1.1e-65 221.4 0.0 2.1e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EKX74277.1 - 4.3e-23 82.5 0.1 1.1e-22 81.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AfaD PF05775.7 EKX74277.1 - 0.092 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein DEAD PF00270.24 EKX74278.1 - 7.1e-12 45.1 0.0 4.6e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EKX74278.1 - 2.5e-11 43.2 0.0 5.4e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GPI2 PF06432.6 EKX74280.1 - 4.2e-28 98.5 8.9 4.9e-28 98.2 6.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DHH PF01368.15 EKX74282.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 DHH family Exo_endo_phos PF03372.18 EKX74283.1 - 1.1e-13 51.6 0.1 1.4e-13 51.3 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family mRNA_cap_enzyme PF01331.14 EKX74284.1 - 6.2e-06 26.0 0.1 1.6e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain Acylphosphatase PF00708.13 EKX74285.1 - 1.8e-20 72.8 0.5 2.2e-20 72.5 0.3 1.1 1 0 0 1 1 1 1 Acylphosphatase Lipocalin PF00061.18 EKX74285.1 - 0.1 12.6 0.0 1.6 8.7 0.0 2.0 1 1 1 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family DSPc PF00782.15 EKX74286.1 - 3.7e-11 42.7 0.0 2e-10 40.3 0.0 1.9 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKX74286.1 - 2.2e-05 23.9 0.0 3.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase AP2 PF00847.15 EKX74287.1 - 8.1e-08 32.2 5.4 0.0045 17.1 0.7 2.9 3 0 0 3 3 3 2 AP2 domain CaATP_NAI PF12515.3 EKX74287.1 - 0.059 12.8 0.9 0.17 11.4 0.6 1.7 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain TPR_11 PF13414.1 EKX74288.1 - 1.1e-12 47.3 6.2 6.8e-07 28.8 1.3 2.2 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EKX74288.1 - 2.9e-12 45.6 0.4 0.0027 17.2 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKX74288.1 - 3.6e-12 45.1 0.1 0.0013 18.5 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKX74288.1 - 1.2e-05 25.7 0.0 0.0064 17.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKX74288.1 - 2.4e-05 24.0 2.3 0.0067 16.2 0.1 2.6 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EKX74288.1 - 4.8e-05 23.5 0.1 3.6 8.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKX74288.1 - 0.0014 18.2 1.5 2.2 8.2 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat YfiO PF13525.1 EKX74288.1 - 0.0038 16.7 1.6 0.12 11.8 1.1 2.4 1 1 0 1 1 1 1 Outer membrane lipoprotein TPR_19 PF14559.1 EKX74288.1 - 0.0039 17.5 0.4 0.82 10.0 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_18 PF13512.1 EKX74288.1 - 0.0099 15.9 1.2 0.29 11.1 0.8 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKX74288.1 - 0.011 15.5 0.5 6.1 6.8 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EKX74288.1 - 0.061 13.4 4.4 0.18 11.9 0.1 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ubiquitin PF00240.18 EKX74289.1 - 9.7e-19 66.5 0.0 1.9e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKX74289.1 - 7.5e-09 35.1 0.0 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 EKX74289.1 - 5.6e-06 26.0 0.0 1.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD_2 PF13881.1 EKX74289.1 - 0.00057 19.7 0.4 0.0023 17.7 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EKX74289.1 - 0.026 14.6 0.1 0.097 12.8 0.0 1.8 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 EKX74289.1 - 0.057 13.6 0.0 0.17 12.1 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain UAA PF08449.6 EKX74290.1 - 3.3e-57 193.7 21.4 4.4e-57 193.3 14.8 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EKX74290.1 - 1.2e-10 41.2 20.3 9e-08 31.8 5.0 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EKX74290.1 - 4.2e-08 33.2 24.9 1.7e-06 28.1 5.1 2.9 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EKX74290.1 - 0.0055 16.8 20.0 0.064 13.4 1.8 3.0 2 1 1 3 3 3 2 Multidrug resistance efflux transporter UFD1 PF03152.9 EKX74291.1 - 4.6e-35 120.3 0.9 1.6e-33 115.3 0.6 2.1 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF3804 PF12707.2 EKX74291.1 - 0.045 13.3 0.2 0.093 12.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3804) OMPdecase PF00215.19 EKX74293.1 - 2.2e-26 92.6 0.0 2.8e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family SNF2_N PF00176.18 EKX74294.1 - 7e-68 228.6 0.1 7e-68 228.6 0.1 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKX74294.1 - 7e-15 54.6 0.1 1.9e-14 53.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 EKX74294.1 - 0.0095 15.7 4.0 0.039 13.7 2.1 2.6 1 1 1 2 2 2 1 HSA CENP-H PF05837.7 EKX74295.1 - 0.12 12.5 0.7 0.77 9.9 0.0 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) PLDc_2 PF13091.1 EKX74296.1 - 1.9e-12 47.0 0.0 1.3e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EKX74296.1 - 0.0086 15.8 6.0 0.041 13.7 0.1 3.6 3 0 0 3 3 3 1 Phospholipase D Active site motif DUF1959 PF09218.5 EKX74296.1 - 0.097 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1959) Ribosomal_L23 PF00276.15 EKX74298.1 - 7.5e-14 51.4 0.4 1.3e-13 50.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 ACDC PF14733.1 EKX74299.1 - 1.3e-10 41.2 0.0 4e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 EKX74299.1 - 1.2e-09 38.1 0.5 1.2e-09 38.1 0.4 1.9 2 0 0 2 2 2 1 AP2 domain DUF3962 PF13111.1 EKX74300.1 - 0.033 13.5 0.1 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3962) DNA_gyraseB PF00204.20 EKX74301.1 - 1.7e-41 141.2 0.1 3.3e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EKX74301.1 - 1.2e-29 102.2 0.0 6.8e-28 96.5 0.0 3.2 3 0 0 3 3 3 1 Toprim domain DNA_gyraseB_C PF00986.16 EKX74301.1 - 2.2e-25 88.1 0.1 4.2e-25 87.2 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.21 EKX74301.1 - 8.4e-11 41.5 0.0 7.7e-10 38.4 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EKX74301.1 - 0.0077 15.8 0.3 0.026 14.1 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim_4 PF13662.1 EKX74301.1 - 0.14 12.2 0.0 0.56 10.2 0.0 2.1 1 1 0 1 1 1 0 Toprim domain HK PF02110.10 EKX74302.1 - 0.00028 20.1 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Peptidase_M41 PF01434.13 EKX74303.1 - 2.9e-68 229.5 1.1 4e-68 229.0 0.8 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EKX74303.1 - 1.4e-42 145.0 0.1 5e-42 143.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EKX74303.1 - 8.2e-07 28.3 0.0 4e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EKX74303.1 - 6.7e-06 26.9 0.0 2.3e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKX74303.1 - 1.8e-05 24.8 2.5 0.022 14.9 0.1 4.1 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.8 EKX74303.1 - 0.00021 20.1 0.0 0.00035 19.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EKX74303.1 - 0.00024 20.8 0.7 0.0011 18.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EKX74303.1 - 0.0011 18.1 0.1 0.0033 16.5 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 EKX74303.1 - 0.0017 17.8 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EKX74303.1 - 0.0018 18.3 0.9 0.042 13.8 0.1 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 EKX74303.1 - 0.0022 17.9 0.6 0.013 15.4 0.0 2.6 2 1 1 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 EKX74303.1 - 0.0028 17.6 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EKX74303.1 - 0.0043 16.2 0.2 0.0087 15.2 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EKX74303.1 - 0.0054 16.6 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EKX74303.1 - 0.013 14.3 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EKX74303.1 - 0.017 14.5 1.1 0.19 11.0 0.3 2.3 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.1 EKX74303.1 - 0.02 14.6 0.6 0.055 13.2 0.4 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EKX74303.1 - 0.023 14.5 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EKX74303.1 - 0.057 13.0 0.3 0.13 11.8 0.2 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EKX74303.1 - 0.084 13.1 0.3 0.23 11.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain Vps16_N PF04841.8 EKX74304.1 - 1.5e-21 76.4 0.0 1.4e-20 73.2 0.0 2.1 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EKX74304.1 - 2.7e-16 59.4 2.1 7.3e-08 31.7 0.0 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region DUF307 PF03733.8 EKX74304.1 - 0.049 14.0 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF307) WD40 PF00400.27 EKX74305.1 - 4.5e-31 105.5 9.8 1.8e-09 37.1 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EKX74305.1 - 6.2e-06 26.0 0.3 0.0018 18.0 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ribosomal_L1 PF00687.16 EKX74306.1 - 3.9e-19 68.8 0.9 5e-19 68.5 0.3 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family ig PF00047.20 EKX74307.1 - 0.029 14.4 0.1 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin domain SH3_3 PF08239.6 EKX74308.1 - 0.0065 16.6 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_2 PF07653.12 EKX74308.1 - 0.047 13.1 0.0 0.09 12.2 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.23 EKX74308.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Rpp20 PF12328.3 EKX74311.1 - 2.5e-06 27.2 0.0 0.016 14.8 0.0 2.7 2 2 0 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P DUF164 PF02591.10 EKX74311.1 - 0.0096 15.7 0.7 0.022 14.5 0.5 1.6 1 0 0 1 1 1 1 Putative zinc ribbon domain SIR2 PF02146.12 EKX74311.1 - 0.083 12.6 0.3 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Sir2 family RPAP2_Rtr1 PF04181.8 EKX74314.1 - 1.5e-14 53.8 1.4 2.8e-14 52.9 0.9 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family Cpn60_TCP1 PF00118.19 EKX74315.1 - 5e-133 444.2 8.7 5.7e-133 444.0 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2120 PF09893.4 EKX74316.1 - 0.064 13.2 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) zf-C3HC4_3 PF13920.1 EKX74319.1 - 1.7e-14 53.1 8.6 3.2e-14 52.3 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKX74319.1 - 1.7e-08 34.3 11.7 4.1e-08 33.1 8.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKX74319.1 - 1.9e-06 27.4 10.7 4.2e-06 26.3 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKX74319.1 - 0.00012 21.7 10.8 0.00025 20.8 7.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EKX74319.1 - 0.0061 16.2 9.5 0.0061 16.2 6.6 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EKX74319.1 - 0.17 11.7 11.6 0.4 10.6 8.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EKX74319.1 - 0.76 9.3 5.8 1.9 8.1 4.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 EKX74319.1 - 1.1 8.7 10.1 3 7.3 7.0 1.7 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.1 EKX74319.1 - 1.4 8.5 8.7 3.8 7.1 6.1 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PqiA PF04403.8 EKX74321.1 - 4.4e-05 23.1 3.8 4.4e-05 23.1 2.6 3.9 3 2 0 3 3 3 2 Paraquat-inducible protein A Neurensin PF14927.1 EKX74321.1 - 0.042 13.2 0.1 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 Neurensin Myosin_head PF00063.16 EKX74322.1 - 2.9e-167 557.7 16.3 6.6e-167 556.5 11.3 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) RCC1 PF00415.13 EKX74322.1 - 2.5e-29 101.2 2.2 2.2e-11 43.7 0.0 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EKX74322.1 - 7.2e-23 79.6 7.1 2.2e-07 30.3 0.1 5.4 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.22 EKX74322.1 - 6e-17 59.6 22.5 0.00018 20.8 0.2 6.8 7 0 0 7 7 7 4 IQ calmodulin-binding motif Myosin_N PF02736.14 EKX74322.1 - 0.0056 16.3 0.8 0.011 15.4 0.6 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 EKX74322.1 - 0.0086 16.2 0.0 0.029 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain CagY_M PF07337.6 EKX74322.1 - 0.014 14.8 0.1 0.25 10.8 0.0 2.5 2 0 0 2 2 2 0 DC-EC Repeat AAA_16 PF13191.1 EKX74322.1 - 0.086 12.8 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 EKX74322.1 - 0.15 11.1 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Pkinase PF00069.20 EKX74324.1 - 4.2e-19 68.6 0.0 3.1e-18 65.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX74324.1 - 1.3e-08 34.1 0.0 2.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ArfGap PF01412.13 EKX74325.1 - 3.4e-30 104.2 0.0 7.9e-30 103.0 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pro_isomerase PF00160.16 EKX74326.1 - 1.5e-37 129.2 0.3 1.7e-37 129.0 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PseudoU_synth_1 PF01416.15 EKX74327.1 - 4.1e-30 104.2 0.4 2.2e-14 53.7 0.1 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase ATP_bind_1 PF03029.12 EKX74328.1 - 1.8e-73 247.0 0.3 2.1e-73 246.8 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EKX74328.1 - 3.5e-07 29.8 0.0 4.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.22 EKX74328.1 - 2.6e-05 23.7 0.1 0.00048 19.6 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EKX74328.1 - 5.3e-05 23.3 0.0 9.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EKX74328.1 - 0.00016 20.5 0.1 0.00036 19.3 0.1 1.5 2 0 0 2 2 2 1 ArgK protein MobB PF03205.9 EKX74328.1 - 0.0011 18.7 0.1 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.7 EKX74328.1 - 0.0015 17.9 0.1 0.0049 16.2 0.0 1.9 2 0 0 2 2 2 1 Poxvirus A32 protein cobW PF02492.14 EKX74328.1 - 0.0015 18.0 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EKX74328.1 - 0.0015 18.5 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.10 EKX74328.1 - 0.0016 18.2 0.1 0.0032 17.2 0.1 1.6 1 1 0 1 1 1 1 NTPase MipZ PF09140.6 EKX74328.1 - 0.0017 17.4 0.0 0.0034 16.4 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ SRP54 PF00448.17 EKX74328.1 - 0.0018 17.7 0.5 0.012 15.0 0.2 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EKX74328.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EKX74328.1 - 0.0033 16.3 0.0 0.0052 15.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 EKX74328.1 - 0.0034 18.2 0.2 0.0091 16.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EKX74328.1 - 0.0041 17.0 0.4 0.0095 15.8 0.3 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 EKX74328.1 - 0.0046 16.6 0.1 0.0074 15.9 0.1 1.5 1 1 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 EKX74328.1 - 0.0061 16.1 0.1 0.0097 15.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EKX74328.1 - 0.011 15.6 0.1 0.022 14.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EKX74328.1 - 0.013 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase TrwB_AAD_bind PF10412.4 EKX74328.1 - 0.021 13.4 0.0 0.035 12.7 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain UPF0079 PF02367.12 EKX74328.1 - 0.025 14.1 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 EKX74328.1 - 0.026 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 EKX74328.1 - 0.027 14.0 0.1 0.04 13.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EKX74328.1 - 0.029 14.7 0.1 0.069 13.4 0.0 1.8 2 1 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 EKX74328.1 - 0.048 12.7 0.0 0.084 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.12 EKX74328.1 - 0.053 13.3 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 Viral_helicase1 PF01443.13 EKX74328.1 - 0.059 12.8 0.1 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EKX74328.1 - 0.08 11.7 0.1 0.15 10.9 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain Septin PF00735.13 EKX74328.1 - 0.092 11.7 0.1 0.88 8.5 0.0 2.1 1 1 0 1 1 1 0 Septin FtsK_SpoIIIE PF01580.13 EKX74328.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mito_carr PF00153.22 EKX74329.1 - 7.9e-38 128.0 7.4 2.3e-19 68.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Pro_isomerase PF00160.16 EKX74330.1 - 1.3e-36 126.1 0.0 2.1e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TFIIA PF03153.8 EKX74331.1 - 7.2e-08 32.7 10.4 2e-07 31.2 7.2 1.8 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit YpjP PF14005.1 EKX74331.1 - 0.082 12.6 0.4 0.73 9.6 0.1 2.4 2 1 1 3 3 3 0 YpjP-like protein Pheromone PF08015.6 EKX74331.1 - 2 9.3 6.9 0.41 11.4 1.3 2.3 1 1 1 2 2 2 0 Fungal mating-type pheromone Kinesin PF00225.18 EKX74332.1 - 2.9e-91 305.6 4.9 5.3e-91 304.7 3.4 1.4 1 0 0 1 1 1 1 Kinesin motor domain EF1_GNE PF00736.14 EKX74333.1 - 3.2e-30 103.6 1.2 6.4e-30 102.6 0.8 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EKX74333.1 - 0.025 14.7 6.0 0.025 14.7 4.2 2.7 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region PARP_reg PF02877.9 EKX74333.1 - 0.088 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain NAD_kinase PF01513.16 EKX74334.1 - 4.3e-07 29.0 0.0 0.0079 15.0 0.0 3.0 3 0 0 3 3 3 2 ATP-NAD kinase DAGK_cat PF00781.19 EKX74334.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Aminotran_5 PF00266.14 EKX74335.1 - 2.1e-119 398.5 0.0 2.4e-119 398.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EKX74335.1 - 1.6e-09 37.2 0.0 2.5e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EKX74335.1 - 0.00078 18.6 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EKX74335.1 - 0.0041 15.4 0.1 0.0065 14.8 0.1 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GDC-P PF02347.11 EKX74335.1 - 0.0069 15.1 0.0 0.012 14.3 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage system P-protein DegT_DnrJ_EryC1 PF01041.12 EKX74335.1 - 0.0074 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L38e PF01781.13 EKX74336.1 - 0.0076 15.9 0.4 0.014 15.1 0.3 1.5 1 0 0 1 1 1 1 Ribosomal L38e protein family tRNA-synt_1g PF09334.6 EKX74337.1 - 5.6e-95 318.2 0.1 4.1e-94 315.4 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EKX74337.1 - 1.4e-28 99.3 0.9 5.7e-18 64.2 0.0 3.5 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EKX74337.1 - 1e-13 51.0 0.0 2.4e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EKX74337.1 - 3.4e-05 22.7 0.0 0.00051 18.8 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1d PF00750.14 EKX74337.1 - 0.0045 15.8 0.0 0.16 10.7 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 EKX74337.1 - 0.17 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) ABC_tran PF00005.22 EKX74338.1 - 3.3e-31 108.4 0.0 1.2e-17 64.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EKX74338.1 - 5.9e-06 26.4 9.1 0.02 14.8 0.1 4.7 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.1 EKX74338.1 - 2.3e-05 24.4 0.1 0.031 14.2 0.0 2.6 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 EKX74338.1 - 9.1e-05 21.9 0.8 0.21 11.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EKX74338.1 - 0.00017 22.3 0.0 0.2 12.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EKX74338.1 - 0.00022 20.7 0.0 0.031 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKX74338.1 - 0.00031 21.0 0.1 0.31 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EKX74338.1 - 0.00042 19.9 0.2 0.096 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EKX74338.1 - 0.00049 20.4 5.1 0.057 13.7 0.5 2.5 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EKX74338.1 - 0.00078 18.4 1.2 0.42 9.4 0.1 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 EKX74338.1 - 0.0012 18.0 0.5 0.12 11.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ArgK PF03308.11 EKX74338.1 - 0.0022 16.8 0.5 0.0058 15.4 0.1 1.7 2 0 0 2 2 2 1 ArgK protein Zeta_toxin PF06414.7 EKX74338.1 - 0.0032 16.5 1.4 2.5 7.1 0.1 3.1 3 0 0 3 3 3 2 Zeta toxin DUF87 PF01935.12 EKX74338.1 - 0.0039 17.0 2.3 0.089 12.5 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EKX74338.1 - 0.0042 17.2 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EKX74338.1 - 0.0048 16.5 0.7 0.16 11.6 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EKX74338.1 - 0.0053 16.2 0.4 0.77 9.1 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 EKX74338.1 - 0.0082 15.8 0.4 2.2 7.8 0.1 2.6 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 EKX74338.1 - 0.0083 15.8 0.3 0.96 9.1 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EKX74338.1 - 0.0093 15.6 1.1 3.9 7.3 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain Miro PF08477.8 EKX74338.1 - 0.012 16.1 0.0 4.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein SMC_N PF02463.14 EKX74338.1 - 0.012 14.8 0.4 0.16 11.2 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ATP_bind_1 PF03029.12 EKX74338.1 - 0.029 13.9 0.1 5.2 6.5 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 EKX74338.1 - 0.032 14.0 1.7 3.5 7.4 0.0 2.7 3 0 0 3 3 2 0 Dynamin family MMR_HSR1 PF01926.18 EKX74338.1 - 0.04 13.8 0.2 0.33 10.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DnaB_C PF03796.10 EKX74338.1 - 0.12 11.1 0.1 5 5.9 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_33 PF13671.1 EKX74338.1 - 0.14 12.0 0.1 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EKX74338.1 - 0.19 10.5 0.8 1.4 7.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain TrwB_AAD_bind PF10412.4 EKX74338.1 - 0.35 9.4 0.4 7.6 5.0 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 EKX74338.1 - 0.98 8.8 5.8 8.4 5.7 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain WD40 PF00400.27 EKX74339.1 - 5.7e-29 98.9 4.6 3.4e-07 29.9 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Herpes_BBRF1 PF04793.7 EKX74340.1 - 0.028 13.2 0.3 0.043 12.5 0.2 1.2 1 0 0 1 1 1 0 BRRF1-like protein PDCD2_C PF04194.8 EKX74341.1 - 2.2e-29 102.1 2.5 9.2e-28 96.8 0.7 2.1 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain Zn-ribbon_8 PF09723.5 EKX74341.1 - 1.3 9.0 0.0 1.3 9.0 0.0 3.6 4 0 0 4 4 4 0 Zinc ribbon domain Cir_N PF10197.4 EKX74342.1 - 4.3e-13 49.0 9.7 4.3e-13 49.0 6.8 2.6 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3573 PF12097.3 EKX74342.1 - 0.012 14.2 0.9 0.018 13.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) GTP_EFTU PF00009.22 EKX74343.1 - 8.8e-51 172.0 0.0 1.5e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EKX74343.1 - 1.6e-16 59.9 0.0 1e-15 57.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 EKX74343.1 - 5.3e-06 26.1 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EKX74343.1 - 0.0083 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EKX74343.1 - 0.046 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Elongation factor G, domain IV PEGA PF08308.6 EKX74344.1 - 0.13 12.0 0.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 PEGA domain NAP PF00956.13 EKX74345.1 - 3.5e-35 121.2 3.0 4.8e-35 120.8 2.1 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Mst1_SARAH PF11629.3 EKX74345.1 - 4.3e-05 23.2 1.7 0.00011 21.9 1.2 1.8 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 DUF165 PF02592.10 EKX74347.1 - 0.019 15.1 0.1 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 Erf4 PF10256.4 EKX74348.1 - 0.085 12.7 0.4 0.11 12.3 0.2 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Pkinase PF00069.20 EKX74349.1 - 5.4e-78 261.7 0.1 7.2e-78 261.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX74349.1 - 1.4e-40 139.0 0.0 1.9e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EKX74349.1 - 3.5e-29 97.8 7.4 1e-07 30.7 0.1 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EKX74349.1 - 4.4e-26 90.7 11.0 1.2e-11 44.5 0.2 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EKX74349.1 - 5.1e-23 78.8 4.3 2.7e-05 23.6 0.0 4.9 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EKX74349.1 - 1.3e-22 78.0 7.1 3.6e-05 22.8 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EKX74349.1 - 3.1e-22 77.9 8.4 1.6e-07 30.8 0.1 5.3 3 1 2 5 5 5 4 EF-hand domain pair Kinase-like PF14531.1 EKX74349.1 - 3.7e-07 29.3 0.0 0.00013 21.0 0.0 2.9 2 1 0 2 2 2 1 Kinase-like SPARC_Ca_bdg PF10591.4 EKX74349.1 - 2.3e-05 24.3 1.0 0.16 12.0 0.1 3.0 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EKX74349.1 - 0.0003 20.4 4.7 0.38 10.4 0.3 4.3 2 1 2 4 4 4 1 Cytoskeletal-regulatory complex EF hand Kdo PF06293.9 EKX74349.1 - 0.0015 17.5 0.0 0.0036 16.3 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKX74349.1 - 0.0041 16.8 0.0 0.016 14.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_9 PF14658.1 EKX74349.1 - 0.0049 16.7 0.1 0.36 10.7 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain TGT PF01702.13 EKX74350.1 - 7.9e-87 290.4 0.0 1.1e-86 290.0 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase TFIIE_alpha PF02002.12 EKX74351.1 - 0.0035 16.8 3.5 0.09 12.2 2.4 2.5 1 1 0 1 1 1 1 TFIIE alpha subunit TrmB PF01978.14 EKX74351.1 - 0.0083 15.8 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Imm3 PF14425.1 EKX74351.1 - 0.013 15.4 0.3 0.033 14.1 0.2 1.7 1 0 0 1 1 1 0 Immunity protein Imm3 HTH_12 PF08461.5 EKX74351.1 - 0.02 14.5 1.7 0.28 10.9 0.1 3.4 4 0 0 4 4 4 0 Ribonuclease R winged-helix domain Herpes_capsid PF06112.6 EKX74351.1 - 0.078 13.0 10.0 0.15 12.1 6.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein GntR PF00392.16 EKX74351.1 - 0.11 11.9 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_24 PF13412.1 EKX74351.1 - 0.13 11.6 0.6 1.1 8.7 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 EKX74351.1 - 0.15 11.8 0.2 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain ubiquitin PF00240.18 EKX74352.1 - 1.8e-35 120.1 0.5 2.3e-35 119.8 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EKX74352.1 - 1.3e-29 101.4 10.7 2.2e-29 100.8 7.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EKX74352.1 - 1.4e-20 72.7 0.4 1.9e-20 72.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EKX74352.1 - 2.1e-06 27.9 0.1 7.1e-06 26.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EKX74352.1 - 0.00028 20.6 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EKX74352.1 - 0.0065 16.3 0.0 0.016 15.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EKX74352.1 - 0.026 14.6 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EKX74352.1 - 0.055 13.3 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 GLUT4 regulating protein TUG zf-CHY PF05495.7 EKX74352.1 - 0.15 12.2 5.9 0.24 11.6 4.1 1.2 1 0 0 1 1 1 0 CHY zinc finger Fer2_3 PF13085.1 EKX74352.1 - 0.84 9.4 5.2 8.8 6.2 0.0 2.5 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain zf-DHHC PF01529.15 EKX74352.1 - 2.4 7.5 5.1 3.6 6.9 3.5 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DDOST_48kD PF03345.9 EKX74354.1 - 2e-08 33.1 0.1 2.7e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF3157 PF11355.3 EKX74354.1 - 0.0096 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3157) Sugar_tr PF00083.19 EKX74355.1 - 7.4e-58 196.1 34.5 9.2e-58 195.8 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKX74355.1 - 1.8e-09 36.7 31.5 1.8e-09 36.7 21.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EKX74355.1 - 0.0002 19.7 1.4 0.0002 19.7 1.0 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HATPase_c PF02518.21 EKX74356.1 - 1.3e-10 40.9 0.0 1.6e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EKX74356.1 - 3.8e-09 36.3 0.0 4.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 EKX74356.1 - 0.014 15.0 0.2 0.027 14.1 0.1 1.5 1 1 0 1 1 1 0 GHKL domain SNARE_assoc PF09335.6 EKX74358.1 - 1.5e-24 86.5 11.4 1.5e-24 86.5 7.9 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein ADSL_C PF10397.4 EKX74358.1 - 0.13 12.2 0.8 0.38 10.7 0.1 1.9 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus DUF4234 PF14018.1 EKX74358.1 - 1.2 8.9 14.4 9 6.1 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) HAMP PF00672.20 EKX74358.1 - 5.1 7.3 10.0 1.3 9.2 0.9 3.0 3 0 0 3 3 3 0 HAMP domain DnaJ PF00226.26 EKX74359.1 - 0.0031 17.1 1.1 0.016 14.9 0.2 2.4 2 1 0 2 2 2 1 DnaJ domain CDC24 PF06395.6 EKX74359.1 - 0.084 12.9 0.2 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 CDC24 Calponin APG9 PF04109.11 EKX74360.1 - 0.0044 15.9 2.5 0.91 8.3 0.6 2.3 2 0 0 2 2 2 2 Autophagy protein Apg9 Myb_DNA-bind_6 PF13921.1 EKX74362.1 - 5.3e-05 23.2 0.7 0.00014 21.9 0.5 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKX74362.1 - 0.0011 18.9 0.3 0.0025 17.8 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Not1 PF04054.10 EKX74363.1 - 1e-41 143.0 3.0 4.5e-34 117.9 0.0 3.3 3 0 0 3 3 3 2 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EKX74363.1 - 2.1e-36 124.7 4.7 7.9e-36 122.9 3.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) FF PF01846.14 EKX74364.1 - 1.2e-06 28.3 13.0 0.00052 19.9 1.0 4.3 4 1 0 4 4 4 2 FF domain WW PF00397.21 EKX74364.1 - 2.3e-06 27.3 5.4 5e-06 26.2 3.7 1.6 1 0 0 1 1 1 1 WW domain Rep_fac_C PF08542.6 EKX74365.1 - 5.9e-20 71.0 0.1 1.7e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EKX74365.1 - 8.6e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 EKX74365.1 - 0.0028 17.6 0.3 0.66 9.9 0.0 2.9 1 1 1 3 3 3 1 AAA ATPase domain Rad17 PF03215.10 EKX74365.1 - 0.012 14.3 0.1 0.018 13.7 0.1 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 EKX74365.1 - 0.056 12.1 0.2 0.14 10.8 0.1 1.6 2 0 0 2 2 2 0 TIP49 C-terminus RuvB_N PF05496.7 EKX74365.1 - 0.11 11.5 0.0 0.28 10.1 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EKX74365.1 - 0.13 12.4 0.0 0.72 10.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain Abhydrolase_6 PF12697.2 EKX74366.1 - 7.6e-13 48.8 0.0 2.2e-12 47.3 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family FAINT PF04385.10 EKX74366.1 - 5.9e-12 45.2 8.9 0.00025 20.8 0.0 5.3 5 0 0 5 5 5 3 Domain of unknown function, DUF529 Abhydrolase_5 PF12695.2 EKX74366.1 - 2.4e-10 40.3 0.0 7.4e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKX74366.1 - 2.6e-09 36.8 0.3 3.9e-08 33.0 0.1 2.5 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EKX74366.1 - 0.0002 20.9 0.0 0.71 9.3 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EKX74366.1 - 0.0071 16.2 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.11 EKX74366.1 - 0.039 13.3 0.1 9.5 5.5 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase FAINT PF04385.10 EKX74367.1 - 0.044 13.6 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function, DUF529 RAP PF08373.5 EKX74369.1 - 3e-15 55.7 1.7 6.7e-15 54.6 1.2 1.6 1 0 0 1 1 1 1 RAP domain DUF559 PF04480.7 EKX74369.1 - 0.001 18.7 0.0 0.0029 17.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF559) TetR PF13972.1 EKX74369.1 - 0.011 15.1 0.2 0.029 13.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial transcriptional repressor FAST_1 PF06743.10 EKX74369.1 - 0.013 15.2 1.7 0.11 12.2 0.1 3.0 2 1 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Myb_Cef PF11831.3 EKX74370.1 - 5.5e-29 101.0 2.9 5.5e-29 101.0 2.0 3.4 3 1 1 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EKX74370.1 - 1.2e-21 76.4 5.4 3.5e-10 39.7 0.6 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKX74370.1 - 7.4e-17 61.2 6.4 6.8e-11 42.1 1.9 3.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Ras PF00071.17 EKX74372.1 - 5.1e-57 191.7 0.3 6.2e-57 191.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKX74372.1 - 2.2e-18 66.9 0.0 3.1e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKX74372.1 - 1.3e-13 50.5 0.0 1.7e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKX74372.1 - 2.3e-07 30.7 0.1 3.1e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKX74372.1 - 1.7e-06 27.6 0.0 1.8e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKX74372.1 - 9.1e-05 21.7 0.0 0.0002 20.6 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EKX74372.1 - 0.00057 19.1 0.0 0.00075 18.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 EKX74372.1 - 0.0075 16.1 0.1 0.025 14.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EKX74372.1 - 0.011 15.0 0.4 0.039 13.2 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 EKX74372.1 - 0.012 15.3 0.1 0.034 13.8 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 EKX74372.1 - 0.11 11.6 0.1 0.31 10.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKX74372.1 - 0.13 12.3 0.0 1.3 9.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain Ribosomal_S8 PF00410.14 EKX74373.1 - 2.6e-17 62.8 0.0 3e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 MIF4G PF02854.14 EKX74374.1 - 2.4e-25 89.2 1.7 5.9e-25 87.9 0.0 2.3 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EKX74374.1 - 3.3e-15 55.7 0.6 3.3e-15 55.7 0.4 2.0 2 0 0 2 2 2 1 MA3 domain Packaging_FI PF14000.1 EKX74374.1 - 0.046 13.9 0.3 0.13 12.5 0.2 1.7 1 0 0 1 1 1 0 DNA packaging protein FI CENP-B_dimeris PF09026.5 EKX74374.1 - 1.7 8.9 8.3 5 7.4 5.8 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3073 PF11273.3 EKX74374.1 - 3.5 8.2 6.6 62 4.2 3.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) RRM_1 PF00076.17 EKX74375.1 - 1.2e-33 114.4 0.1 2.1e-16 59.3 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKX74375.1 - 1.9e-23 82.1 0.0 6.3e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKX74375.1 - 3.5e-15 55.5 0.2 2.3e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 EKX74375.1 - 1.9e-09 37.2 1.5 4.4e-09 36.0 1.0 1.6 1 0 0 1 1 1 1 WW domain Nup35_RRM PF05172.8 EKX74375.1 - 0.00014 21.5 0.2 0.046 13.4 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.6 EKX74375.1 - 0.0019 17.7 0.0 0.88 9.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1866) Nup35_RRM_2 PF14605.1 EKX74375.1 - 0.023 14.4 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.7 EKX74375.1 - 0.055 13.4 0.1 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif 2 OB_RNB PF08206.6 EKX74375.1 - 0.11 12.0 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain Med3 PF11593.3 EKX74375.1 - 0.89 8.7 5.5 1.3 8.2 3.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PDEase_I PF00233.14 EKX74377.1 - 1.5e-57 195.0 0.1 2.2e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 EKX74377.1 - 0.00021 21.2 0.0 0.00056 19.9 0.0 1.7 1 0 0 1 1 1 1 HD domain Exo_endo_phos PF03372.18 EKX74378.1 - 8.6e-16 58.6 0.0 9.9e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DLH PF01738.13 EKX74379.1 - 0.037 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Ribonuc_red_sm PF00268.16 EKX74382.1 - 9.8e-35 119.9 8.0 9.8e-35 119.9 5.5 2.0 2 1 0 2 2 2 1 Ribonucleotide reductase, small chain EMP24_GP25L PF01105.19 EKX74383.1 - 3.1e-22 79.1 0.0 3.8e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TBCC PF07986.7 EKX74384.1 - 7.4e-27 93.1 0.3 1.4e-26 92.2 0.2 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Pinin_SDK_memA PF04696.8 EKX74385.1 - 5.2e-07 29.3 12.9 5.2e-07 29.3 9.0 1.8 2 1 0 2 2 2 1 pinin/SDK/memA/ protein conserved region TRF PF08558.5 EKX74385.1 - 0.081 12.2 5.8 0.14 11.4 4.0 1.4 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) HALZ PF02183.13 EKX74385.1 - 0.13 11.9 0.3 0.13 11.9 0.2 3.7 3 1 0 3 3 3 0 Homeobox associated leucine zipper Jacalin PF01419.12 EKX74385.1 - 0.13 12.1 1.1 0.26 11.1 0.7 1.5 1 0 0 1 1 1 0 Jacalin-like lectin domain RuvC PF02075.12 EKX74385.1 - 0.16 11.8 0.5 0.3 10.9 0.4 1.5 1 1 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC IlvC PF01450.14 EKX74385.1 - 0.23 11.3 5.9 0.39 10.6 2.5 2.4 2 1 1 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain Sulfatase_C PF14707.1 EKX74385.1 - 0.45 10.8 2.3 0.81 9.9 1.2 1.9 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Prefoldin_2 PF01920.15 EKX74385.1 - 0.61 9.8 17.7 4.7 7.0 8.7 2.6 2 0 0 2 2 2 0 Prefoldin subunit DUF2536 PF10750.4 EKX74385.1 - 0.86 9.2 9.1 3.9 7.1 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2536) Med9 PF07544.8 EKX74385.1 - 0.98 9.1 15.9 2.3 8.0 0.2 2.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 IATP PF04568.7 EKX74385.1 - 1.4 8.9 15.3 0.17 11.9 4.9 3.2 4 0 0 4 4 4 0 Mitochondrial ATPase inhibitor, IATP DUF4407 PF14362.1 EKX74385.1 - 1.6 7.5 11.3 1.4 7.7 2.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) RRF_GI PF12614.3 EKX74385.1 - 2 8.2 7.5 2.7 7.8 3.2 2.5 2 1 0 2 2 2 0 Ribosome recycling factor TMPIT PF07851.8 EKX74385.1 - 6.6 5.7 14.0 3 6.8 6.6 2.1 1 1 1 2 2 2 0 TMPIT-like protein HemX PF04375.9 EKX74385.1 - 6.8 5.1 10.5 2 6.9 4.9 1.8 2 1 1 3 3 3 0 HemX Syntaxin PF00804.20 EKX74385.1 - 9 6.5 20.3 0.14 12.3 4.1 3.0 3 1 0 3 3 3 0 Syntaxin BPL_LplA_LipB PF03099.14 EKX74386.1 - 6.4e-20 71.4 0.0 1.1e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.4 EKX74386.1 - 2.3e-07 30.3 0.4 1.1e-06 28.1 0.1 2.2 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus RCC1_2 PF13540.1 EKX74387.1 - 1.1e-26 91.7 15.0 3.6e-08 32.8 0.0 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EKX74387.1 - 1.6e-21 76.2 4.2 7.2e-08 32.5 0.0 7.9 8 2 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat SBBP PF06739.6 EKX74387.1 - 0.01 15.6 5.9 0.075 12.8 0.9 2.6 2 0 0 2 2 2 0 Beta-propeller repeat CWC25 PF12542.3 EKX74388.1 - 3.1e-16 59.5 0.2 3.1e-16 59.5 0.1 4.3 3 2 0 3 3 3 1 Pre-mRNA splicing factor CKS PF01111.14 EKX74389.1 - 1.4e-18 66.4 0.0 1.9e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit GTP_EFTU PF00009.22 EKX74390.1 - 4.5e-24 84.9 2.3 1.9e-22 79.5 1.6 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EKX74390.1 - 1.9e-11 43.8 0.1 3.1e-10 39.8 0.0 2.3 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 EKX74390.1 - 2e-06 27.7 0.0 4.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EKX74390.1 - 1.7e-05 24.6 0.4 0.00027 20.7 0.0 2.6 2 1 1 3 3 3 1 Dynamin family Miro PF08477.8 EKX74390.1 - 7.6e-05 23.2 0.0 0.00017 22.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EKX74390.1 - 0.00041 19.6 0.0 0.00073 18.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EKX74390.1 - 0.00075 19.0 0.1 0.024 14.1 0.0 2.9 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EKX74390.1 - 0.0071 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Ras PF00071.17 EKX74390.1 - 0.056 12.8 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Ras family zf-B_box PF00643.19 EKX74391.1 - 1.3e-11 44.1 15.0 9.4e-08 31.8 2.9 2.5 2 0 0 2 2 2 2 B-box zinc finger PH PF00169.24 EKX74391.1 - 6e-06 26.4 0.2 2.3e-05 24.5 0.1 2.1 1 0 0 1 1 1 1 PH domain Baculo_PEP_C PF04513.7 EKX74391.1 - 0.027 14.3 7.6 1.2 8.9 0.2 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IBR PF01485.16 EKX74391.1 - 0.83 9.5 8.4 6.4 6.7 1.1 2.5 2 0 0 2 2 2 0 IBR domain zf-UBR PF02207.15 EKX74391.1 - 4.3 7.1 13.4 0.3 10.8 1.8 2.7 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) CLASP_N PF12348.3 EKX74392.1 - 9.8e-06 25.0 2.5 0.00019 20.8 0.2 2.1 1 1 1 2 2 2 2 CLASP N terminal Cnd1 PF12717.2 EKX74392.1 - 0.0041 16.9 4.1 0.0043 16.9 1.7 1.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DUF918 PF06033.6 EKX74392.1 - 0.0045 16.5 0.5 0.0087 15.5 0.3 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF918) DUF29 PF01724.11 EKX74392.1 - 0.24 11.2 1.9 0.46 10.3 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF29 FAINT PF04385.10 EKX74393.1 - 1.4e-05 24.8 0.1 2e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.10 EKX74394.1 - 1.7e-07 30.9 0.0 2.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Neuropeptide_S PF14993.1 EKX74394.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Neuropeptide S precursor protein Neur_chan_memb PF02932.11 EKX74394.1 - 0.31 10.8 2.1 0.4 10.5 1.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.4 EKX74394.1 - 1.9 6.6 9.4 2.1 6.5 6.5 1.0 1 0 0 1 1 1 0 Transmembrane protein FAINT PF04385.10 EKX74397.1 - 1.8e-17 62.9 0.1 0.00013 21.7 0.0 5.4 4 2 1 5 5 5 3 Domain of unknown function, DUF529 Atracotoxin PF05353.6 EKX74398.1 - 5.2 6.9 8.9 0.15 11.9 1.3 2.1 2 0 0 2 2 2 0 Delta Atracotoxin MFS_1 PF07690.11 EKX74402.1 - 2.9e-16 59.1 38.2 4.3e-16 58.5 24.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3007 PF11460.3 EKX74402.1 - 0.099 12.7 0.6 0.27 11.3 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) MHCassoc_trimer PF08831.5 EKX74404.1 - 0.0056 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Class II MHC-associated invariant chain trimerisation domain BBS2_Mid PF14783.1 EKX74405.1 - 0.002 17.9 0.8 7.8 6.3 0.0 3.4 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region DUF4234 PF14018.1 EKX74405.1 - 0.12 12.1 0.0 0.41 10.4 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) Pkinase PF00069.20 EKX74406.1 - 6.4e-54 182.8 0.3 1.2e-53 181.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKX74406.1 - 1.2e-27 96.5 0.0 4.6e-27 94.7 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EKX74406.1 - 0.0004 20.2 0.0 0.028 14.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EKX74406.1 - 0.0017 17.3 0.0 0.011 14.7 0.0 2.1 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EKX74406.1 - 0.0095 15.2 3.6 0.12 11.7 0.0 2.8 3 0 0 3 3 3 1 RIO1 family DUF2305 PF10230.4 EKX74406.1 - 0.041 13.2 2.0 0.065 12.6 1.4 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) CBFD_NFYB_HMF PF00808.18 EKX74409.1 - 5.3e-23 80.8 0.0 8.2e-23 80.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EKX74409.1 - 8e-05 22.6 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 EKX74409.1 - 0.013 15.7 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Bromo_TP PF07524.8 EKX74409.1 - 0.022 14.5 0.0 0.059 13.1 0.0 1.8 1 1 1 2 2 2 0 Bromodomain associated Peptidase_C13 PF01650.13 EKX74411.1 - 3.1e-07 29.9 0.7 9.7e-07 28.3 0.5 1.7 1 1 0 1 1 1 1 Peptidase C13 family ParA PF10609.4 EKX74413.1 - 8.9e-31 105.6 0.1 2e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EKX74413.1 - 5.3e-14 52.0 0.0 9.1e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EKX74413.1 - 2.3e-06 27.6 0.0 9.8e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EKX74413.1 - 2.6e-05 23.4 0.1 0.00027 20.0 0.0 2.3 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EKX74413.1 - 0.00011 21.3 0.1 0.00066 18.8 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ YhjQ PF06564.7 EKX74413.1 - 0.014 14.7 0.1 0.19 11.0 0.0 2.1 2 0 0 2 2 2 0 YhjQ protein AAA_25 PF13481.1 EKX74413.1 - 0.16 11.3 0.1 0.34 10.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain Choline_kinase PF01633.15 EKX74414.1 - 1.9e-32 112.6 0.0 2.6e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EKX74414.1 - 6.8e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EKX74414.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase CcoS PF03597.10 EKX74415.1 - 0.024 14.1 1.3 0.043 13.2 0.9 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF4138 PF13595.1 EKX74415.1 - 0.055 12.4 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4138) Ribosomal_S7 PF00177.16 EKX74416.1 - 2.7e-42 143.8 1.1 3.2e-42 143.5 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Arf PF00025.16 EKX74417.1 - 1.6e-14 53.5 0.0 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKX74417.1 - 6.9e-06 25.3 0.0 8.1e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKX74417.1 - 2.1e-05 23.8 0.0 2.5e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EKX74417.1 - 0.00016 21.1 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKX74417.1 - 0.00032 21.1 0.0 0.00048 20.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EKX74417.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TFIIF_beta PF02270.10 EKX74418.1 - 9.4e-09 35.4 4.1 0.0021 17.9 0.0 2.4 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit Retinal PF15449.1 EKX74418.1 - 0.022 12.4 0.2 0.026 12.1 0.1 1.1 1 0 0 1 1 1 0 Retinal protein MBF1 PF08523.5 EKX74419.1 - 1.5e-17 63.3 0.4 1.5e-17 63.3 0.3 1.7 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EKX74419.1 - 9e-13 47.8 0.1 1.5e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EKX74419.1 - 1.4e-07 31.3 0.0 2.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EKX74419.1 - 2.6e-07 30.7 0.0 5e-07 29.8 0.0 1.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.1 EKX74419.1 - 0.034 13.7 0.8 0.099 12.2 0.3 1.8 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.1 EKX74419.1 - 0.13 12.5 0.1 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain polyprenyl_synt PF00348.12 EKX74420.1 - 2.7e-50 170.6 0.1 3.3e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase COPI_assoc PF08507.5 EKX74422.1 - 0.13 11.9 12.3 0.38 10.4 8.5 1.7 1 1 0 1 1 1 0 COPI associated protein DUF4239 PF14023.1 EKX74422.1 - 0.43 9.9 2.4 0.68 9.2 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) CD20 PF04103.10 EKX74422.1 - 1.5 8.7 8.0 8.4 6.3 5.5 2.1 1 1 0 1 1 1 0 CD20-like family AP2 PF00847.15 EKX74423.1 - 2.5e-08 33.9 2.7 6.1e-08 32.6 1.9 1.7 1 0 0 1 1 1 1 AP2 domain DUF3343 PF11823.3 EKX74423.1 - 0.11 11.7 0.1 0.36 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) vATP-synt_E PF01991.13 EKX74424.1 - 3.8e-36 124.2 9.8 4.5e-36 123.9 6.8 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF2710 PF10921.3 EKX74424.1 - 0.0054 16.8 0.9 0.013 15.5 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2710) CheR_N PF03705.10 EKX74424.1 - 0.013 14.8 0.2 0.039 13.3 0.1 1.8 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain DUF848 PF05852.6 EKX74424.1 - 0.023 14.5 9.7 0.18 11.6 3.2 2.4 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Peptidase_C41 PF05417.6 EKX74424.1 - 0.039 13.5 0.1 0.063 12.8 0.1 1.3 1 0 0 1 1 1 0 Hepatitis E cysteine protease Dehydratase_SU PF02287.10 EKX74424.1 - 0.067 12.9 0.5 0.067 12.9 0.4 2.0 2 0 0 2 2 2 0 Dehydratase small subunit HrpE PF06188.7 EKX74424.1 - 0.091 12.4 1.9 0.22 11.2 1.3 1.6 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Ycf1 PF05758.7 EKX74424.1 - 0.12 10.0 3.5 0.16 9.6 2.4 1.1 1 0 0 1 1 1 0 Ycf1 DUF4047 PF13256.1 EKX74424.1 - 0.42 10.5 9.1 0.55 10.1 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) YtxH PF12732.2 EKX74424.1 - 2.8 8.3 4.5 27 5.2 3.1 2.5 1 1 0 1 1 1 0 YtxH-like protein DivIVA PF05103.8 EKX74424.1 - 7.4 6.6 11.6 0.96 9.4 0.1 3.0 2 1 1 3 3 3 0 DivIVA protein SecY PF00344.15 EKX74425.1 - 1.7e-92 310.0 14.5 1.7e-92 310.0 10.1 1.3 2 0 0 2 2 2 1 SecY translocase Plug_translocon PF10559.4 EKX74425.1 - 1.6e-18 65.9 0.1 6.4e-18 63.9 0.1 2.2 1 0 0 1 1 1 1 Plug domain of Sec61p Glycoprotein_B PF00606.13 EKX74425.1 - 2.5 6.0 4.1 0.7 7.8 0.5 1.7 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B Mog1 PF04603.7 EKX74426.1 - 1.2e-16 60.8 0.0 2e-16 60.2 0.0 1.3 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Spindle_Spc25 PF08234.7 EKX74427.1 - 1.9e-17 63.0 0.0 6.2e-17 61.3 0.0 1.9 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 RasGAP_C PF03836.10 EKX74427.1 - 0.013 15.1 3.2 0.027 14.1 1.8 1.9 1 1 1 2 2 2 0 RasGAP C-terminus Cofilin_ADF PF00241.15 EKX74427.1 - 0.028 14.3 0.4 2.7 7.9 0.0 2.4 2 1 0 2 2 2 0 Cofilin/tropomyosin-type actin-binding protein Spc7 PF08317.6 EKX74427.1 - 0.037 12.6 4.5 0.055 12.1 3.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4200 PF13863.1 EKX74427.1 - 0.055 13.4 8.2 0.1 12.5 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Cep57_CLD_2 PF14197.1 EKX74427.1 - 0.2 11.6 4.1 0.23 11.4 1.5 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Med9 PF07544.8 EKX74427.1 - 0.23 11.1 3.8 0.48 10.1 2.6 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.7 EKX74427.1 - 0.26 11.0 7.3 0.5 10.1 4.3 1.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HIT PF01230.18 EKX74430.1 - 7.1e-26 90.6 0.1 8.8e-26 90.3 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EKX74430.1 - 1.5e-22 79.9 0.4 1.9e-22 79.7 0.3 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding