# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- COX1 PF00115.15 ABU97452.1 - 1.4e-132 442.5 58.1 1.8e-132 442.1 40.3 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I zf-CHCC PF10276.4 ABU97452.1 - 0.018 14.8 0.0 0.063 13.1 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger domain COX3 PF00510.13 ABU97453.1 - 4.6e-13 49.2 20.8 2.7e-12 46.6 14.4 2.0 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III DUF1230 PF06799.6 ABU97453.1 - 3.2 7.5 6.4 0.35 10.7 0.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1230) Cytochrom_B_N_2 PF13631.1 ABU97454.1 - 4.4e-32 111.1 24.4 5.8e-32 110.7 12.6 2.4 2 0 0 2 2 2 2 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.12 ABU97454.1 - 4e-16 59.1 5.1 4e-16 59.1 3.5 3.7 2 1 0 3 3 3 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_N PF00033.14 ABU97454.1 - 1.3e-06 27.8 28.8 5.6e-06 25.8 20.0 2.0 1 1 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB MGC-24 PF05283.6 EDO05048.1 - 2.4 7.9 20.3 10 5.8 0.7 4.3 2 2 2 4 4 4 0 Multi-glycosylated core protein 24 (MGC-24) VESA1_N PF12785.2 EDO05049.1 - 1.5e-17 63.7 2.0 3.4e-12 46.0 0.1 4.0 3 1 1 4 4 4 3 Variant erythrocyte surface antigen-1 Sporozoite_P67 PF05642.6 EDO05049.1 - 0.07 10.9 0.1 0.11 10.3 0.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen VESA1_N PF12785.2 EDO05050.1 - 4e-176 586.5 25.5 6.1e-174 579.3 17.7 2.0 1 1 0 1 1 1 1 Variant erythrocyte surface antigen-1 DDE_Tnp_1_assoc PF13808.1 EDO05050.1 - 0.007 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 DDE_Tnp_1-associated VESA1_N PF12785.2 EDO05051.1 - 8e-222 737.1 16.6 8e-222 737.1 11.5 2.1 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 WXG100 PF06013.7 EDO05051.1 - 0.048 13.6 0.0 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Baculo_PEP_C PF04513.7 EDO05051.1 - 0.12 12.1 1.1 3.4 7.4 0.0 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 EDO05051.1 - 0.14 11.6 0.2 0.75 9.2 0.1 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Prefoldin_2 PF01920.15 EDO05051.1 - 0.14 11.9 7.1 0.072 12.8 1.1 2.5 2 1 0 2 2 2 0 Prefoldin subunit DUF4164 PF13747.1 EDO05051.1 - 0.27 11.3 0.8 1.5 8.9 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) GvpK PF05121.7 EDO05051.1 - 0.4 10.5 5.6 4.4 7.1 2.4 2.6 2 0 0 2 2 2 0 Gas vesicle protein K Spore_III_AF PF09581.5 EDO05051.1 - 3.5 7.4 7.6 0.73 9.6 2.7 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) VESA1_N PF12785.2 EDO05052.1 - 3.3e-15 56.0 13.6 3.3e-15 56.0 9.4 6.2 3 1 2 5 5 5 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05054.1 - 2.6e-23 82.7 15.8 1.2e-19 70.6 7.0 2.7 1 1 1 2 2 2 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05055.1 - 7.2e-215 714.2 20.9 7.2e-215 714.2 14.5 2.7 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05057.1 - 7.3e-31 107.6 15.4 2.9e-29 102.3 5.7 4.8 3 2 1 4 4 4 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05058.1 - 4.7e-224 744.5 17.3 4.7e-224 744.5 12.0 2.2 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 DUF3439 PF11921.3 EDO05058.1 - 0.033 13.9 8.9 0.098 12.4 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) RBP_receptor PF14752.1 EDO05059.1 - 0.1 10.9 0.0 0.11 10.8 0.0 1.0 1 0 0 1 1 1 0 Retinol binding protein receptor SLR1-BP PF07333.7 EDO05059.1 - 0.22 11.7 4.2 2 8.7 2.2 2.2 2 0 0 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) VESA1_N PF12785.2 EDO05060.1 - 2.4e-23 82.8 23.4 6.3e-13 48.5 0.0 3.6 1 1 2 3 3 3 3 Variant erythrocyte surface antigen-1 CBF_beta PF02312.12 EDO05060.1 - 0.19 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Core binding factor beta subunit VESA1_N PF12785.2 EDO05061.1 - 1.1e-225 749.8 18.5 1.1e-225 749.8 12.8 2.3 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 Spc7 PF08317.6 EDO05061.1 - 0.18 10.4 1.9 1.7 7.2 0.0 2.5 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF4398 PF14346.1 EDO05061.1 - 0.96 9.5 3.6 0.52 10.3 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) VESA1_N PF12785.2 EDO05062.1 - 1.1e-14 54.2 41.4 2.6e-11 43.1 0.0 5.1 4 1 1 5 5 5 3 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05063.1 - 5e-216 718.0 18.0 5e-216 718.0 12.5 2.5 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 Ribosomal_S2 PF00318.15 EDO05064.1 - 2.7e-32 111.7 22.4 3e-32 111.5 15.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 RNA_pol_Rpb1_5 PF04998.12 EDO05066.1 - 3.2e-24 85.6 0.0 5.8e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EDO05067.1 - 6.5e-33 114.0 0.3 2e-32 112.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 EDO05067.1 - 0.0042 16.3 14.2 0.0062 15.8 0.3 3.5 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb2_6 PF00562.23 EDO05068.1 - 1.2e-54 185.6 10.6 1.2e-54 185.6 7.3 2.6 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.15 EDO05068.1 - 1.2e-09 38.2 0.8 7.3e-09 35.7 0.1 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EDO05068.1 - 6.8e-05 22.5 0.1 0.00019 21.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 AAA_2 PF07724.9 EDO05070.1 - 2.4e-38 131.7 0.0 8.6e-38 129.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EDO05070.1 - 2.7e-11 43.7 0.3 2.3e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO05070.1 - 2.1e-08 34.0 0.0 5.1e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EDO05070.1 - 7.3e-07 28.8 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 EDO05070.1 - 9.3e-05 21.6 0.0 0.00019 20.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EDO05070.1 - 0.0027 16.9 0.1 0.28 10.3 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EDO05070.1 - 0.0073 16.4 0.1 0.073 13.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain HPPK PF01288.15 EDO05070.1 - 0.04 13.6 3.1 5.8 6.6 0.0 2.9 3 0 0 3 3 3 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) RNA_helicase PF00910.17 EDO05070.1 - 0.04 14.0 0.7 0.04 14.0 0.5 3.2 3 2 1 4 4 4 0 RNA helicase AAA_3 PF07726.6 EDO05070.1 - 0.053 13.1 0.1 0.17 11.4 0.0 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EDO05070.1 - 0.065 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.7 EDO05070.1 - 0.1 11.6 0.5 0.84 8.6 0.0 2.5 4 0 0 4 4 4 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EDO05070.1 - 0.11 13.3 0.4 0.71 10.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.1 EDO05070.1 - 0.2 11.6 0.0 0.91 9.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EDO05070.1 - 0.23 11.3 0.1 0.57 10.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EDO05071.1 - 2.1e-40 138.4 0.1 5.5e-40 137.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EDO05071.1 - 2.3e-09 37.1 0.0 1.1e-08 34.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EDO05071.1 - 2.1e-07 31.2 0.0 5.9e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDO05071.1 - 7e-07 28.8 0.0 1.6e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 EDO05071.1 - 0.00041 19.4 0.0 0.00073 18.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 EDO05071.1 - 0.0015 18.6 0.1 0.0079 16.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO05071.1 - 0.01 16.6 0.6 0.12 13.1 0.0 2.9 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EDO05071.1 - 0.018 15.3 0.5 0.036 14.3 0.4 1.7 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EDO05071.1 - 0.021 14.8 0.0 0.063 13.2 0.0 1.6 1 1 0 2 2 2 0 AAA ATPase domain DUF2153 PF09921.4 EDO05071.1 - 0.058 12.9 0.0 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) DUF87 PF01935.12 EDO05071.1 - 0.084 12.6 9.8 0.049 13.4 1.8 3.4 3 1 0 3 3 3 0 Domain of unknown function DUF87 T2SE PF00437.15 EDO05071.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CotJB PF12652.2 EDO05071.1 - 0.14 12.2 1.2 0.53 10.3 0.8 2.1 1 0 0 1 1 1 0 CotJB protein AAA_19 PF13245.1 EDO05071.1 - 0.24 11.2 0.0 0.44 10.3 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain DUF2533 PF10752.4 EDO05071.1 - 0.35 11.1 3.3 10 6.5 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) AAA_18 PF13238.1 EDO05071.1 - 0.49 10.7 0.0 0.49 10.7 0.0 3.0 3 1 0 3 3 3 0 AAA domain DUF2177 PF09945.4 EDO05072.1 - 0.031 14.2 0.6 0.04 13.9 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) AsiA PF09010.5 EDO05072.1 - 3.4 7.5 6.9 1.2 9.0 1.5 2.2 2 1 1 3 3 3 0 Anti-Sigma Factor A Clathrin-link PF09268.5 EDO05074.1 - 0.39 9.8 1.9 2.5 7.2 0.1 2.4 2 0 0 2 2 2 0 Clathrin, heavy-chain linker GTP_EFTU PF00009.22 EDO05077.1 - 5.2e-56 189.0 0.8 7.3e-56 188.5 0.6 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDO05077.1 - 2.1e-25 88.7 0.0 8.3e-25 86.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDO05077.1 - 1.1e-14 54.2 0.5 4.9e-13 48.9 0.5 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EDO05077.1 - 1.3e-07 31.1 0.2 1.4e-06 27.8 0.2 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EDO05077.1 - 2.9e-05 24.0 0.1 6.4e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDO05077.1 - 0.00042 20.7 0.0 0.00096 19.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein PmbA_TldD PF01523.11 EDO05077.1 - 0.037 13.2 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative modulator of DNA gyrase MobB PF03205.9 EDO05077.1 - 0.072 12.7 0.3 0.23 11.1 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ExoD PF06055.7 EDO05078.1 - 0.018 14.1 0.1 0.022 13.8 0.1 1.1 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Caveolin PF01146.12 EDO05078.1 - 0.024 14.2 3.1 0.026 14.1 1.7 1.3 1 1 0 1 1 1 0 Caveolin DUF360 PF04020.8 EDO05078.1 - 0.61 10.4 5.1 0.95 9.8 3.5 1.5 1 1 0 1 1 1 0 Membrane protein of unknown function PDR_assoc PF08370.6 EDO05078.1 - 4.7 6.7 6.1 0.52 9.8 1.0 1.8 2 1 0 2 2 2 0 Plant PDR ABC transporter associated Vac14_Fab1_bd PF12755.2 EDO05079.1 - 0.21 11.9 4.2 5.5 7.4 0.5 2.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Scs3p PF10261.4 EDO05080.1 - 0.059 12.4 0.2 0.062 12.3 0.1 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Scs3p PF10261.4 EDO05081.1 - 0.059 12.3 0.2 0.062 12.3 0.1 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Scs3p PF10261.4 EDO05082.1 - 0.059 12.3 0.2 0.062 12.3 0.1 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Ribosomal_S7 PF00177.16 EDO05083.1 - 0.0015 18.1 0.8 0.0032 17.0 0.6 1.6 1 1 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosom_S12_S23 PF00164.20 EDO05084.1 - 1e-33 115.3 6.8 1.1e-33 115.2 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 FeoC PF09012.5 EDO05084.1 - 0.038 13.6 0.1 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator DUF538 PF04398.7 EDO05084.1 - 0.066 13.4 0.1 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF538 Ribosomal_S11 PF00411.14 EDO05085.1 - 0.0097 16.0 1.0 0.12 12.5 0.7 2.3 1 1 0 1 1 1 1 Ribosomal protein S11 DUF3991 PF13154.1 EDO05085.1 - 0.52 10.5 3.8 0.14 12.3 0.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3991) Tet_JBP PF12851.2 EDO05086.1 - 1.2 8.4 3.8 0.41 9.9 0.9 1.5 2 0 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily YjcQ PF09639.5 EDO05087.1 - 0.62 10.1 6.5 1.7 8.8 4.2 2.3 1 1 0 1 1 1 0 YjcQ protein Ribosomal_S8 PF00410.14 EDO05088.1 - 6.6e-10 38.9 0.3 7.4e-10 38.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L14 PF00238.14 EDO05090.1 - 2.3e-11 43.4 1.2 3.8e-11 42.7 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L16 PF00252.13 EDO05091.1 - 2.7e-32 111.2 0.1 3.3e-32 111.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_S3_C PF00189.15 EDO05092.1 - 7.8e-16 58.0 3.3 7.8e-16 58.0 2.3 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain Ribosomal_L2_C PF03947.13 EDO05093.1 - 7.5e-31 106.6 0.0 1.2e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EDO05093.1 - 8.3e-05 22.4 5.3 8.3e-05 22.4 3.7 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain DUF2058 PF09831.4 EDO05093.1 - 0.079 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) NYD-SP28_assoc PF14775.1 EDO05094.1 - 0.96 9.1 7.7 0.2 11.3 1.4 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain Myb_DNA-bind_4 PF13837.1 EDO05094.1 - 1.1 9.4 4.4 0.47 10.6 1.4 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain S4 PF01479.20 EDO05095.1 - 2.3e-07 30.1 0.1 8.4e-07 28.3 0.0 2.1 1 0 0 1 1 1 1 S4 domain VESA1_N PF12785.2 EDO05096.1 - 7.1e-22 78.0 9.4 7.1e-22 78.0 6.5 5.1 3 1 1 4 4 4 3 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05097.1 - 7.9e-227 753.7 15.9 7.9e-227 753.7 11.1 2.8 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 DUF1542 PF07564.6 EDO05097.1 - 0.02 14.9 4.0 0.073 13.0 2.8 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Spc7 PF08317.6 EDO05097.1 - 2.8 6.5 6.3 0.7 8.5 1.7 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3989 PF13150.1 EDO05098.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) VESA1_N PF12785.2 EDO05099.1 - 5.6e-15 55.2 18.2 3.4e-11 42.7 0.0 4.7 4 1 1 5 5 5 3 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05100.1 - 1.1e-216 720.2 13.9 2.6e-216 719.0 9.6 1.7 1 0 0 1 1 1 1 Variant erythrocyte surface antigen-1 Myosin_tail_1 PF01576.14 EDO05100.1 - 0.011 13.4 11.4 0.017 12.8 7.9 1.2 1 0 0 1 1 1 0 Myosin tail CDC37_N PF03234.9 EDO05100.1 - 0.16 12.2 8.6 0.34 11.2 2.2 2.8 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding Acyl-CoA_dh_2 PF08028.6 EDO05100.1 - 0.23 11.7 0.4 0.6 10.3 0.3 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DUF4407 PF14362.1 EDO05100.1 - 0.26 10.2 9.7 0.5 9.2 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.6 EDO05100.1 - 0.31 11.4 3.6 9.9 6.6 0.0 3.2 3 0 0 3 3 3 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.14 EDO05100.1 - 8.4 4.0 4.4 6.3 4.5 1.1 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NARP1 PF12569.3 EDO05100.1 - 9.8 4.8 9.2 22 3.6 6.4 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 VESA1_N PF12785.2 EDO05101.1 - 5.5e-26 91.5 19.2 1.4e-11 44.0 0.0 3.1 2 1 1 3 3 3 3 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05102.1 - 1.1e-212 707.0 21.6 1.1e-212 707.0 14.9 2.8 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 WXG100 PF06013.7 EDO05102.1 - 0.041 13.8 0.2 0.58 10.2 0.0 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Apolipoprotein PF01442.13 EDO05102.1 - 0.068 12.6 1.5 0.19 11.2 0.5 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 EDO05102.1 - 0.16 11.7 2.4 2.2 8.1 0.1 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PEP-utilisers_N PF05524.8 EDO05102.1 - 0.3 10.8 1.2 7.3 6.4 0.2 2.4 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Sipho_Gp157 PF05565.6 EDO05102.1 - 0.31 10.5 3.5 0.64 9.5 2.4 1.5 1 0 0 1 1 1 0 Siphovirus Gp157 HSCB_C PF07743.8 EDO05102.1 - 0.72 10.3 3.3 7.5 7.0 0.1 3.5 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain Prefoldin_2 PF01920.15 EDO05102.1 - 1.5 8.6 13.3 0.13 12.0 3.5 3.1 3 0 0 3 3 3 0 Prefoldin subunit SecY PF00344.15 EDO05103.1 - 2.3e-92 309.6 14.2 3e-92 309.2 9.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EDO05103.1 - 5.2e-19 67.4 0.1 2.3e-18 65.3 0.0 2.2 1 0 0 1 1 1 1 Plug domain of Sec61p vATP-synt_E PF01991.13 EDO05104.1 - 5.4e-29 100.8 8.6 6.2e-29 100.6 6.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit NARG2_C PF10505.4 EDO05104.1 - 0.0078 15.4 0.2 0.018 14.2 0.0 1.6 1 1 1 2 2 2 1 NMDA receptor-regulated gene protein 2 C-terminus AP2 PF00847.15 EDO05105.1 - 0.0015 18.6 3.1 0.0015 18.6 2.1 2.1 1 1 1 2 2 2 1 AP2 domain polyprenyl_synt PF00348.12 EDO05106.1 - 2.6e-44 151.0 0.0 1.1e-25 90.0 0.0 2.1 1 1 1 2 2 2 2 Polyprenyl synthetase MBF1 PF08523.5 EDO05107.1 - 1.4e-18 66.6 0.2 2.8e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EDO05107.1 - 5.4e-12 45.3 0.2 8.6e-12 44.7 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EDO05107.1 - 2.2e-08 34.1 0.0 3.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EDO05107.1 - 9.2e-07 28.8 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 EDO05107.1 - 0.0054 16.3 0.0 0.0087 15.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TFIIF_beta PF02270.10 EDO05108.1 - 7.1e-06 26.0 0.7 1.1e-05 25.3 0.5 1.3 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit RPA_C PF08784.6 EDO05108.1 - 0.0061 16.9 0.0 0.0094 16.3 0.0 1.5 1 1 0 1 1 1 1 Replication protein A C terminal ThiF PF00899.16 EDO05109.1 - 3.4e-06 26.9 0.0 5.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family Ish1 PF10281.4 EDO05110.1 - 0.0069 16.4 0.3 0.078 13.0 0.2 2.6 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein GAT PF03127.9 EDO05110.1 - 0.49 10.4 5.2 2.5 8.1 0.9 3.0 3 0 0 3 3 3 0 GAT domain Pkinase PF00069.20 EDO05111.1 - 2.7e-52 177.4 0.0 2e-51 174.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO05111.1 - 4.5e-26 91.4 0.0 1.5e-18 66.8 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDO05111.1 - 0.0041 16.1 0.0 0.66 8.8 0.0 3.0 3 0 0 3 3 3 1 Kinase-like RIO1 PF01163.17 EDO05111.1 - 0.01 15.1 0.4 0.14 11.5 0.0 2.2 1 1 0 2 2 2 0 RIO1 family APH PF01636.18 EDO05111.1 - 0.019 14.7 1.1 0.51 10.0 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family CBFD_NFYB_HMF PF00808.18 EDO05112.1 - 2.6e-23 81.8 0.2 4.2e-23 81.1 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDO05112.1 - 3.8e-05 23.7 0.0 7.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Peptidase_C13 PF01650.13 EDO05114.1 - 5.8e-09 35.6 1.1 1.8e-06 27.4 0.1 2.2 2 0 0 2 2 2 2 Peptidase C13 family ParA PF10609.4 EDO05116.1 - 7.5e-30 102.6 0.1 1.3e-29 101.8 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EDO05116.1 - 3.6e-16 59.1 0.0 4.1e-15 55.6 0.0 2.0 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EDO05116.1 - 3.5e-08 33.5 0.2 2e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EDO05116.1 - 1.8e-06 27.2 0.9 0.002 17.2 0.1 2.7 2 1 1 3 3 3 2 Anion-transporting ATPase MipZ PF09140.6 EDO05116.1 - 2.5e-05 23.4 0.4 4.8e-05 22.5 0.1 1.6 2 0 0 2 2 2 1 ATPase MipZ YhjQ PF06564.7 EDO05116.1 - 8.2e-05 22.0 0.1 0.0025 17.2 0.1 2.1 2 0 0 2 2 2 1 YhjQ protein AAA_26 PF13500.1 EDO05116.1 - 0.0038 16.8 0.1 0.23 11.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EDO05116.1 - 0.05 13.0 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain VirC1 PF07015.6 EDO05116.1 - 0.085 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein ArgK PF03308.11 EDO05116.1 - 0.094 11.4 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 ArgK protein CobA_CobO_BtuR PF02572.10 EDO05116.1 - 0.19 11.3 0.2 24 4.5 0.2 2.3 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Ribosomal_S7 PF00177.16 EDO05117.1 - 4e-43 146.5 0.5 4.7e-43 146.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Arf PF00025.16 EDO05118.1 - 1.9e-13 50.0 0.0 2.1e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EDO05118.1 - 3.7e-05 24.2 0.0 5.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EDO05118.1 - 0.0002 20.6 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 EDO05118.1 - 0.0047 16.8 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EDO05118.1 - 0.018 14.9 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EDO05118.1 - 0.032 13.3 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 EDO05118.1 - 0.063 13.1 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain HsbA PF12296.3 EDO05119.1 - 0.0063 16.3 3.5 0.049 13.4 0.1 3.3 3 0 0 3 3 3 1 Hydrophobic surface binding protein A DUF1192 PF06698.6 EDO05119.1 - 0.015 15.0 0.1 0.038 13.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) FlxA PF14282.1 EDO05119.1 - 9.2 6.2 9.6 0.5 10.3 0.3 2.7 2 0 0 2 2 2 0 FlxA-like protein Rep_2 PF01719.12 EDO05120.1 - 0.018 14.5 0.6 0.093 12.2 0.1 2.1 2 0 0 2 2 2 0 Plasmid replication protein Alpha_adaptinC2 PF02883.15 EDO05120.1 - 0.046 14.0 0.0 0.38 11.0 0.0 2.6 2 0 0 2 2 2 0 Adaptin C-terminal domain Pro_isomerase PF00160.16 EDO05122.1 - 1.8e-46 158.1 1.9 3.1e-46 157.3 1.3 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.23 EDO05122.1 - 7.5e-29 99.6 0.0 1.6e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 EDO05122.1 - 1.2e-17 63.3 9.5 5.3e-09 35.6 0.1 2.4 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EDO05122.1 - 1.3e-07 30.9 0.0 0.008 15.7 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO05122.1 - 2.7e-06 26.8 0.6 0.29 11.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDO05122.1 - 0.00042 20.1 0.0 0.00087 19.0 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO05122.1 - 0.00051 20.6 1.0 0.56 10.9 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDO05122.1 - 0.00058 19.6 0.3 0.0016 18.2 0.0 1.8 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 EDO05122.1 - 0.015 15.2 2.7 0.25 11.3 0.1 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDO05122.1 - 0.017 15.5 0.4 26 5.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDO05122.1 - 0.047 14.0 0.5 6.2 7.2 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EDO05122.1 - 0.059 13.5 2.4 0.26 11.4 0.7 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EDO05122.1 - 0.081 12.7 2.4 8.5 6.4 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EDO05122.1 - 0.14 12.0 4.1 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain PIG-S PF10510.4 EDO05123.1 - 0.093 11.3 0.5 0.32 9.6 0.1 1.8 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein Actin PF00022.14 EDO05124.1 - 1.4e-151 504.4 0.0 1.6e-151 504.2 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EDO05124.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Phosphodiest PF01663.17 EDO05124.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase FAD_binding_3 PF01494.14 EDO05125.1 - 6.2e-41 140.6 0.0 1.2e-24 87.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EDO05125.1 - 0.034 13.2 0.1 0.4 9.7 0.0 2.2 2 1 0 2 2 2 0 Thi4 family SE PF08491.5 EDO05125.1 - 0.041 12.7 0.3 0.42 9.4 0.2 2.1 1 1 0 1 1 1 0 Squalene epoxidase DAO PF01266.19 EDO05125.1 - 0.049 12.5 0.0 0.14 11.0 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.16 EDO05125.1 - 0.12 12.1 0.5 0.54 10.0 0.4 2.0 1 1 1 2 2 2 0 ThiF family RNase_P_p30 PF01876.11 EDO05128.1 - 3.9e-15 55.3 0.0 5.4e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Pkinase PF00069.20 EDO05129.1 - 1.3e-43 149.0 0.0 1.5e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO05129.1 - 3.4e-20 72.2 0.0 4.4e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO05129.1 - 4.4e-05 23.3 0.0 0.00054 19.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EDO05129.1 - 8.1e-05 21.7 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDO05129.1 - 0.00044 19.2 0.0 0.0006 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EDO05129.1 - 0.032 13.7 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase TAXi_C PF14541.1 EDO05130.1 - 0.11 12.0 0.0 0.33 10.4 0.0 1.8 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal XPG_I PF00867.13 EDO05131.1 - 1.5e-27 95.4 0.2 3e-27 94.4 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EDO05131.1 - 1.4e-24 86.2 0.0 3.4e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EDO05131.1 - 7.3e-06 26.1 0.0 4.6e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.11 EDO05131.1 - 0.0026 17.1 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain HHH_2 PF12826.2 EDO05131.1 - 0.049 13.5 0.0 0.31 10.9 0.0 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.1 EDO05131.1 - 0.093 12.9 0.0 0.56 10.4 0.0 2.3 1 1 0 1 1 1 0 Helix-hairpin-helix domain zf-RanBP PF00641.13 EDO05132.1 - 6.7e-09 34.6 17.3 6.6e-05 21.9 5.4 2.5 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EDO05132.1 - 0.0073 16.1 12.1 0.12 12.1 3.2 2.2 1 1 1 2 2 2 2 Double zinc ribbon Ribosomal_L37e PF01907.14 EDO05132.1 - 0.56 10.0 12.7 1.2 9.0 3.9 2.2 1 1 1 2 2 2 0 Ribosomal protein L37e DUF3279 PF11682.3 EDO05132.1 - 1.4 8.5 9.9 1.1 8.7 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3279) zf-C2H2_3 PF13878.1 EDO05132.1 - 4.7 6.8 12.1 1.5 8.4 1.9 2.9 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO GBP PF02263.14 EDO05133.1 - 3.8e-06 26.1 0.2 2e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain DUF3554 PF12074.3 EDO05133.1 - 0.0069 15.8 0.2 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3554) PRESAN PF09687.5 EDO05133.1 - 0.007 16.4 6.0 0.0079 16.2 1.0 2.8 2 0 0 2 2 2 1 Plasmodium RESA N-terminal AAA PF00004.24 EDO05134.1 - 1e-36 126.0 0.0 1.7e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDO05134.1 - 2.5e-05 23.4 0.0 4.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EDO05134.1 - 5.7e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EDO05134.1 - 7e-05 22.5 0.0 0.00035 20.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EDO05134.1 - 0.00013 22.7 0.0 0.00036 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO05134.1 - 0.00014 21.5 0.2 0.00049 19.8 0.1 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_22 PF13401.1 EDO05134.1 - 0.0002 21.5 0.1 0.0031 17.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDO05134.1 - 0.0012 18.7 0.0 0.0029 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDO05134.1 - 0.0015 18.3 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDO05134.1 - 0.0027 17.1 0.9 0.0094 15.3 0.3 2.0 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EDO05134.1 - 0.0045 17.2 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO05134.1 - 0.0095 15.9 0.1 0.043 13.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EDO05134.1 - 0.011 15.2 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 EDO05134.1 - 0.013 15.2 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 EDO05134.1 - 0.015 14.3 0.0 0.058 12.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 EDO05134.1 - 0.021 14.4 0.2 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EDO05134.1 - 0.021 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EDO05134.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EDO05134.1 - 0.041 14.1 0.0 0.13 12.6 0.0 1.8 2 0 0 2 2 1 0 ABC transporter MCM PF00493.18 EDO05134.1 - 0.045 12.5 0.0 0.091 11.5 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family TIP49 PF06068.8 EDO05134.1 - 0.053 12.2 0.0 0.087 11.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 EDO05134.1 - 0.053 13.6 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase UPF0079 PF02367.12 EDO05134.1 - 0.058 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EDO05134.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EDO05134.1 - 0.13 11.6 0.1 0.46 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 EDO05134.1 - 0.13 11.9 0.0 7.8 6.1 0.0 2.6 1 1 1 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 EDO05134.1 - 0.18 10.6 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EDO05134.1 - 0.19 11.3 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Form_Nir_trans PF01226.12 EDO05135.1 - 2.3e-59 200.2 19.7 2.6e-59 200.1 13.6 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter zf-rbx1 PF12678.2 EDO05136.1 - 1.2e-07 31.7 3.9 2.3e-06 27.6 2.8 3.0 2 0 0 2 2 2 1 RING-H2 zinc finger FANCL_C PF11793.3 EDO05136.1 - 1e-06 28.6 5.2 5.1e-06 26.3 3.6 2.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EDO05136.1 - 3.9e-06 26.5 8.8 3.9e-06 26.5 6.1 2.6 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 EDO05136.1 - 3.4e-05 23.5 2.1 0.00018 21.3 1.5 2.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EDO05136.1 - 0.0048 16.5 11.9 0.012 15.2 7.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EDO05136.1 - 0.081 12.9 7.7 0.36 10.8 5.3 2.2 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.1 EDO05136.1 - 0.46 10.5 17.2 0.033 14.1 7.5 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EDO05136.1 - 0.59 9.6 5.2 2 8.0 3.6 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Bax1-I PF01027.15 EDO05137.1 - 4.5e-23 81.9 27.2 5.4e-23 81.6 18.9 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 MRP-L28 PF09812.4 EDO05138.1 - 0.041 13.7 2.3 0.041 13.7 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 TruD PF01142.13 EDO05139.1 - 5.4e-50 170.1 0.0 4.1e-48 163.9 0.0 3.1 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) Longin PF13774.1 EDO05140.1 - 6.5e-12 44.8 0.0 1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EDO05140.1 - 7.2e-08 31.9 0.5 1.2e-07 31.1 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF3407 PF11887.3 EDO05140.1 - 0.027 13.7 0.2 0.038 13.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) Gp-FAR-1 PF05823.7 EDO05140.1 - 0.083 12.8 1.0 0.13 12.1 0.7 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Seryl_tRNA_N PF02403.17 EDO05140.1 - 0.089 12.8 0.3 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IMS PF00817.15 EDO05141.1 - 6.1e-36 123.4 1.1 2.5e-35 121.4 0.2 2.4 3 0 0 3 3 3 1 impB/mucB/samB family IMS_HHH PF11798.3 EDO05141.1 - 0.00053 19.8 0.0 0.0021 17.9 0.0 2.1 2 0 0 2 2 2 1 IMS family HHH motif Borealin PF10512.4 EDO05141.1 - 0.0094 15.8 0.2 0.022 14.6 0.2 1.6 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 IMS_C PF11799.3 EDO05141.1 - 0.029 14.2 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain DUF1805 PF08827.6 EDO05141.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) AAA PF00004.24 EDO05142.1 - 1.5e-43 148.1 0.0 8.6e-43 145.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO05142.1 - 3.3e-10 39.8 0.1 3.4e-09 36.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDO05142.1 - 8.7e-07 29.0 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDO05142.1 - 7e-06 26.1 0.2 7.4e-05 22.8 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDO05142.1 - 1.3e-05 25.3 0.1 0.00033 20.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO05142.1 - 4e-05 24.4 0.1 0.00031 21.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDO05142.1 - 9.8e-05 21.5 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDO05142.1 - 0.00017 21.3 0.1 0.00043 19.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EDO05142.1 - 0.00052 19.4 0.0 0.00095 18.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EDO05142.1 - 0.00084 19.2 0.4 0.003 17.4 0.0 2.0 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 EDO05142.1 - 0.0011 17.7 0.0 0.0022 16.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 EDO05142.1 - 0.0033 16.5 0.1 0.0092 15.1 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 EDO05142.1 - 0.0036 17.2 0.0 0.0091 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDO05142.1 - 0.0041 17.0 0.0 0.0085 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EDO05142.1 - 0.0048 16.5 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EDO05142.1 - 0.0088 15.2 0.1 0.022 13.9 0.0 1.6 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EDO05142.1 - 0.0094 16.2 0.0 0.032 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EDO05142.1 - 0.014 15.0 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EDO05142.1 - 0.015 14.5 0.0 0.083 12.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 EDO05142.1 - 0.017 14.2 0.0 0.052 12.6 0.0 1.8 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.17 EDO05142.1 - 0.02 15.0 0.0 0.045 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 EDO05142.1 - 0.022 14.2 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 EDO05142.1 - 0.023 14.1 0.1 0.098 12.0 0.0 1.8 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 EDO05142.1 - 0.029 14.0 0.0 0.6 9.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 EDO05142.1 - 0.036 12.9 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EDO05142.1 - 0.042 12.7 0.0 0.087 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 EDO05142.1 - 0.048 13.7 0.0 0.22 11.5 0.0 2.2 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EDO05142.1 - 0.064 13.5 0.1 0.26 11.5 0.0 2.4 2 1 0 2 2 2 0 ABC transporter DUF1759 PF03564.10 EDO05143.1 - 0.052 13.3 0.4 10 5.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) PP2C PF00481.16 EDO05145.1 - 2e-43 148.6 0.1 3.9e-43 147.6 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EDO05145.1 - 0.014 14.8 0.0 0.12 11.7 0.0 2.4 1 1 1 2 2 2 0 Protein phosphatase 2C SpoIIE PF07228.7 EDO05145.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Tho2 PF11262.3 EDO05146.1 - 8.5e-91 304.0 0.1 1.3e-90 303.4 0.1 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EDO05146.1 - 1.8e-06 27.6 0.0 4.7e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Spectrin PF00435.16 EDO05146.1 - 0.034 14.4 0.7 0.094 13.0 0.5 1.7 1 0 0 1 1 1 0 Spectrin repeat Fcf2 PF08698.6 EDO05147.1 - 3.1e-12 46.3 0.3 3.1e-12 46.3 0.2 1.8 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing BNIP2 PF12496.3 EDO05147.1 - 0.059 13.5 0.5 0.11 12.6 0.4 1.4 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Peptidase_C1 PF00112.18 EDO05148.1 - 7.9e-41 140.3 1.4 1.7e-40 139.2 1.0 1.6 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.6 EDO05148.1 - 1.3e-07 31.7 0.0 5.5e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.10 EDO05148.1 - 0.33 9.4 3.2 0.25 9.7 0.8 1.7 2 0 0 2 2 2 0 Peptidase C1-like family zf-CCCH PF00642.19 EDO05150.1 - 2.3e-05 23.9 0.4 6.1e-05 22.5 0.2 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Bud13 PF09736.4 EDO05151.1 - 2.7e-45 154.1 1.9 4e-45 153.6 1.3 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex SRPRB PF09439.5 EDO05153.1 - 4.9e-11 42.1 0.1 5.1e-11 42.1 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EDO05153.1 - 5.1e-08 32.3 0.0 6.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EDO05153.1 - 0.00078 19.9 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EDO05153.1 - 0.0012 18.2 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 EDO05153.1 - 0.0014 18.0 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO05153.1 - 0.0044 16.9 0.0 0.0062 16.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EDO05153.1 - 0.013 14.6 0.1 0.015 14.4 0.1 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 EDO05154.1 - 6.2e-33 114.0 0.1 1e-32 113.2 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EDO05154.1 - 9e-23 81.0 15.3 1.2e-22 80.6 10.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EDO05154.1 - 4.2e-09 35.9 0.2 1.7e-07 30.7 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDO05154.1 - 4.5e-09 36.6 0.5 0.00017 21.6 0.1 2.3 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDO05154.1 - 0.00021 21.3 0.1 0.00043 20.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EDO05154.1 - 0.00084 18.5 0.0 0.0076 15.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 EDO05154.1 - 0.01 16.0 0.2 0.17 12.1 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EDO05154.1 - 0.018 14.5 0.1 0.058 12.9 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EDO05154.1 - 0.019 14.7 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EDO05154.1 - 0.021 14.1 0.0 0.069 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DLIC PF05783.6 EDO05154.1 - 0.029 13.0 0.0 0.06 12.0 0.0 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.1 EDO05154.1 - 0.031 14.4 1.7 0.31 11.1 1.2 2.3 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EDO05154.1 - 0.034 14.6 0.0 0.13 12.7 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein ATP-synt_ab PF00006.20 EDO05154.1 - 0.05 13.1 0.4 0.45 9.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 EDO05154.1 - 0.054 13.1 1.7 2.7 7.6 0.1 2.7 3 0 0 3 3 3 0 NACHT domain ABC_ATPase PF09818.4 EDO05154.1 - 0.081 11.4 0.0 0.18 10.3 0.0 1.6 1 1 0 1 1 1 0 Predicted ATPase of the ABC class AAA_15 PF13175.1 EDO05154.1 - 0.45 9.5 1.5 3.4 6.6 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain Ftsk_gamma PF09397.5 EDO05155.1 - 0.033 13.8 0.2 0.084 12.5 0.1 1.6 1 0 0 1 1 1 0 Ftsk gamma domain ATP11 PF06644.6 EDO05158.1 - 9.3e-16 58.1 0.0 1e-15 57.9 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Pyr_redox_2 PF07992.9 EDO05162.1 - 4.3e-06 26.7 0.0 8.7e-05 22.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO05162.1 - 5.5e-05 23.1 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EDO05162.1 - 0.004 16.9 0.0 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EDO05162.1 - 0.0052 17.1 0.0 0.22 11.9 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EDO05162.1 - 0.0078 15.7 0.0 0.024 14.2 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 EDO05162.1 - 0.049 13.6 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FF PF01846.14 EDO05162.1 - 0.055 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 FF domain ThiF PF00899.16 EDO05162.1 - 0.37 10.6 1.5 3.3 7.5 0.1 2.4 2 0 0 2 2 2 0 ThiF family Ribosomal_S14 PF00253.16 EDO05164.1 - 1.7e-17 62.5 0.3 3.5e-17 61.5 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PP2C PF00481.16 EDO05165.1 - 7.6e-59 199.1 0.0 8.9e-51 172.7 0.0 2.6 2 1 0 2 2 2 2 Protein phosphatase 2C PIG-F PF06699.6 EDO05166.1 - 0.011 15.6 11.0 0.026 14.4 7.5 1.8 1 1 0 1 1 1 0 GPI biosynthesis protein family Pig-F HALZ PF02183.13 EDO05167.1 - 0.00031 20.3 1.6 0.00031 20.3 1.1 2.6 2 0 0 2 2 2 1 Homeobox associated leucine zipper Seryl_tRNA_N PF02403.17 EDO05167.1 - 0.0038 17.2 5.2 0.0038 17.2 3.6 2.3 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 EDO05167.1 - 0.0044 16.4 12.1 0.027 13.9 4.7 2.7 1 1 1 2 2 2 1 Septum formation initiator Syntaxin-6_N PF09177.6 EDO05167.1 - 0.0074 16.6 3.3 0.17 12.3 2.5 2.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DivIVA PF05103.8 EDO05167.1 - 0.017 15.1 6.6 0.017 15.1 4.6 2.5 1 1 1 2 2 2 0 DivIVA protein Bcl-2_3 PF15286.1 EDO05167.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Occludin_ELL PF07303.8 EDO05167.1 - 0.33 11.7 7.8 0.71 10.6 3.2 2.9 1 1 1 2 2 2 0 Occludin homology domain IncA PF04156.9 EDO05167.1 - 0.55 9.7 17.9 3.7 7.0 10.9 2.5 1 1 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EDO05167.1 - 0.57 7.9 5.3 0.93 7.2 3.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.6 EDO05167.1 - 0.97 9.3 3.3 9.2 6.2 0.4 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF342 PF03961.8 EDO05167.1 - 1.4 7.2 5.2 2.5 6.3 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 EDO05167.1 - 6 6.5 12.8 3.8 7.2 4.4 3.4 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF4446 PF14584.1 EDO05167.1 - 7.1 6.4 7.8 0.58 9.9 1.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) APG6 PF04111.7 EDO05167.1 - 7.9 5.4 14.4 1.3 7.9 7.1 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 Metallophos PF00149.23 EDO05168.1 - 4.5e-41 140.4 0.2 5.7e-41 140.1 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDO05168.1 - 0.0077 16.0 0.0 0.0088 15.8 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Urm1 PF09138.6 EDO05169.1 - 1.6e-23 82.6 0.0 2e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) KASH PF10541.4 EDO05170.1 - 2.8 7.8 5.5 0.35 10.7 0.9 1.7 2 0 0 2 2 2 0 Nuclear envelope localisation domain Guanylate_cyc PF00211.15 EDO05171.1 - 1.5e-76 255.8 1.0 5.7e-39 133.3 0.3 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain E1-E2_ATPase PF00122.15 EDO05171.1 - 3.6e-14 52.3 0.1 3.6e-14 52.3 0.0 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EDO05171.1 - 1.7e-13 51.4 0.0 4.3e-12 46.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDO05171.1 - 1.6e-11 44.7 1.3 5.7e-11 42.9 0.9 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDO05171.1 - 1.5e-07 31.2 0.0 4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ELMO_CED12 PF04727.8 EDO05172.1 - 5.8e-32 110.5 0.2 8.2e-32 110.0 0.1 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3631 PF12307.3 EDO05172.1 - 0.093 12.6 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) zf-C2H2_4 PF13894.1 EDO05173.1 - 2 8.9 3.8 1 9.8 0.6 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Atg14 PF10186.4 EDO05174.1 - 0.00052 19.0 2.8 0.0012 17.9 1.9 1.5 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EDO05174.1 - 0.0017 17.9 4.2 0.0027 17.3 2.9 1.3 1 0 0 1 1 1 1 IncA protein Transcrip_act PF04949.8 EDO05174.1 - 0.0019 17.8 3.8 0.0036 16.9 2.6 1.4 1 0 0 1 1 1 1 Transcriptional activator Cast PF10174.4 EDO05174.1 - 0.026 12.5 9.9 0.033 12.2 6.2 1.3 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF3972 PF13118.1 EDO05174.1 - 0.028 14.5 2.4 0.028 14.5 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) DUF641 PF04859.7 EDO05174.1 - 0.035 13.8 3.8 0.067 12.9 2.6 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Mod_r PF07200.8 EDO05174.1 - 0.069 13.0 10.4 0.16 11.9 7.0 1.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ATG16 PF08614.6 EDO05174.1 - 0.084 12.6 10.9 0.15 11.8 7.6 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 EDO05174.1 - 0.11 11.5 8.7 0.18 10.8 6.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 FlgN PF05130.7 EDO05174.1 - 0.11 12.6 8.6 0.26 11.5 6.0 1.6 1 0 0 1 1 1 0 FlgN protein FlaC_arch PF05377.6 EDO05174.1 - 0.27 11.1 2.4 0.57 10.1 1.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Bacillus_HBL PF05791.6 EDO05174.1 - 0.39 10.0 6.2 1.6 8.0 2.6 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TBPIP PF07106.8 EDO05174.1 - 1.1 8.8 9.5 1.7 8.2 6.2 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sin_N PF04801.8 EDO05175.1 - 4.5e-18 65.3 2.5 4.4e-13 48.8 0.0 4.1 4 0 0 4 4 4 3 Sin-like protein conserved region Kelch_4 PF13418.1 EDO05176.1 - 1.4e-46 156.0 18.3 1.3e-11 44.0 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EDO05176.1 - 3.6e-32 109.7 16.1 1.2e-05 25.2 0.6 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.20 EDO05176.1 - 3e-26 90.7 12.3 3.5e-06 26.4 0.1 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EDO05176.1 - 3e-25 87.2 21.1 1.2e-05 25.2 0.3 6.4 4 2 2 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EDO05176.1 - 3.1e-24 84.4 14.7 8.9e-06 25.5 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EDO05176.1 - 6.4e-17 60.5 16.5 5.4e-05 22.7 0.5 6.2 6 1 0 6 6 6 5 Kelch motif EB PF01683.13 EDO05176.1 - 0.0077 16.2 0.5 0.014 15.4 0.4 1.5 1 0 0 1 1 1 1 EB module EGF_2 PF07974.8 EDO05176.1 - 0.029 14.5 11.3 0.029 14.5 7.8 2.2 2 0 0 2 2 2 0 EGF-like domain EGF_alliinase PF04863.8 EDO05176.1 - 0.16 11.9 1.7 0.35 10.8 1.2 1.6 1 0 0 1 1 1 0 Alliinase EGF-like domain hEGF PF12661.2 EDO05176.1 - 0.6 10.3 3.6 1.5 9.0 2.5 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF KxDL PF10241.4 EDO05177.1 - 0.09 12.6 1.4 9.1 6.2 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein FtsA PF14450.1 EDO05177.1 - 0.16 11.8 0.2 0.33 10.8 0.1 1.5 1 1 0 1 1 1 0 Cell division protein FtsA CPW_WPC PF09717.5 EDO05178.1 - 1.5e-14 54.3 7.0 2.9e-14 53.4 4.9 1.5 1 0 0 1 1 1 1 Plasmodium falciparum domain of unknown function (CPW_WPC) DUF4319 PF14203.1 EDO05178.1 - 0.16 11.5 1.1 0.27 10.8 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) Phage_XkdX PF09693.5 EDO05178.1 - 1.1 8.8 3.7 2.3 7.8 0.2 2.5 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) Hexokinase_1 PF00349.16 EDO05180.1 - 1.1e-54 184.8 0.0 1.7e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EDO05180.1 - 3.9e-47 160.5 0.1 5.9e-47 159.9 0.1 1.3 1 0 0 1 1 1 1 Hexokinase DUF3883 PF13020.1 EDO05181.1 - 8.5e-20 70.3 0.1 1.6e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.1 EDO05181.1 - 0.012 15.3 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDO05181.1 - 0.051 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AKAP7_NLS PF10469.4 EDO05182.1 - 0.00065 19.4 0.0 0.0035 17.0 0.0 2.0 2 0 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.11 EDO05182.1 - 0.0021 17.9 0.1 0.067 13.1 0.0 2.8 2 0 0 2 2 2 1 LigT like Phosphoesterase PB1 PF00564.19 EDO05182.1 - 0.063 12.9 0.0 1.4 8.5 0.0 2.7 2 0 0 2 2 2 0 PB1 domain RNase_HII PF01351.13 EDO05183.1 - 4.9e-46 156.8 0.0 5.8e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII Exo5 PF09810.4 EDO05184.1 - 2.1e-78 263.8 9.4 1.2e-76 258.0 6.5 2.2 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EDO05184.1 - 4.4e-09 36.1 0.2 6.5e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Brix PF04427.13 EDO05185.1 - 1.1e-48 165.5 0.3 1.5e-48 165.0 0.2 1.2 1 0 0 1 1 1 1 Brix domain PAP_central PF04928.12 EDO05187.1 - 7.3e-102 339.5 0.0 9.5e-102 339.1 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EDO05187.1 - 2.2e-35 121.5 0.6 3.9e-35 120.6 0.4 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EDO05187.1 - 1.1e-05 25.6 0.0 2.9e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain ORC2 PF04084.9 EDO05188.1 - 6.7e-48 163.2 0.0 8.2e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 CTDII PF01556.13 EDO05190.1 - 2.6e-24 84.8 0.6 4.2e-19 68.2 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EDO05190.1 - 3.3e-21 74.7 0.7 6e-21 73.9 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EDO05190.1 - 0.042 13.9 2.7 0.077 13.0 1.8 1.4 1 0 0 1 1 1 0 DnaJ central domain GatB_N PF02934.10 EDO05193.1 - 9.5e-51 172.3 0.0 1.8e-46 158.3 0.0 2.3 2 1 0 2 2 2 2 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EDO05193.1 - 5e-05 23.0 0.0 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 GatB domain TrmE_N PF10396.4 EDO05194.1 - 4.3e-31 107.2 0.1 1.4e-30 105.6 0.0 1.9 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 EDO05194.1 - 2.2e-24 85.6 0.9 7.8e-24 83.8 0.6 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 EDO05194.1 - 1.4e-16 60.6 0.6 1.4e-16 60.6 0.4 2.7 3 0 0 3 3 3 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 EDO05194.1 - 2.7e-13 49.4 1.9 5.1e-13 48.5 1.3 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EDO05194.1 - 1e-09 38.4 5.7 0.00021 21.1 0.1 3.1 3 1 1 4 4 3 2 Dynamin family Gtr1_RagA PF04670.7 EDO05194.1 - 4.7e-07 29.1 0.3 4.7e-07 29.1 0.2 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDO05194.1 - 3.2e-06 27.6 0.2 9.8e-06 26.0 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EDO05194.1 - 0.00023 20.3 1.0 0.00052 19.1 0.6 1.7 1 1 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EDO05194.1 - 0.00034 19.8 0.4 0.00098 18.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EDO05194.1 - 0.00057 20.1 1.4 0.0013 19.0 0.3 2.2 1 1 1 2 2 2 1 ABC transporter GTP_EFTU PF00009.22 EDO05194.1 - 0.0017 17.8 1.6 0.29 10.5 1.1 3.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EDO05194.1 - 0.008 16.9 1.3 0.082 13.7 0.0 2.9 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EDO05194.1 - 0.0094 16.2 1.4 0.0094 16.2 1.0 2.3 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 EDO05194.1 - 0.018 14.4 0.8 2 7.8 0.0 2.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2383 PF09537.5 EDO05194.1 - 0.019 15.2 0.1 0.062 13.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) AAA PF00004.24 EDO05194.1 - 0.02 15.1 0.5 0.19 11.9 0.0 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EDO05194.1 - 0.033 13.6 1.6 0.15 11.4 0.3 2.5 2 1 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 EDO05194.1 - 0.069 13.1 0.0 0.24 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDO05194.1 - 0.073 12.4 0.0 0.22 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF1890 PF09001.6 EDO05194.1 - 0.079 12.9 2.8 0.28 11.2 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1890) AAA_16 PF13191.1 EDO05194.1 - 0.23 11.3 2.0 4 7.3 0.0 3.0 2 1 1 3 3 3 0 AAA ATPase domain DUF445 PF04286.7 EDO05194.1 - 1.4 8.3 13.8 7.7 5.9 8.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF445) CENP-Q PF13094.1 EDO05194.1 - 1.6 8.7 5.7 3.5 7.6 1.6 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit JHBP PF06585.6 EDO05195.1 - 0.033 12.9 0.0 0.18 10.6 0.0 1.8 2 0 0 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) GEMIN8 PF15348.1 EDO05195.1 - 0.22 11.5 2.8 0.23 11.5 1.2 1.5 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Kei1 PF08552.6 EDO05195.1 - 1.5 8.4 3.2 2.4 7.7 2.2 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 D123 PF07065.9 EDO05195.1 - 3.1 6.7 5.4 3.5 6.6 1.3 2.1 1 1 1 2 2 2 0 D123 ThiF PF00899.16 EDO05196.1 - 9.6e-33 112.8 2.3 1.3e-32 112.4 0.2 2.0 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 EDO05196.1 - 1.6e-05 25.0 7.2 0.00047 20.2 1.2 3.2 2 1 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase E2_bind PF08825.5 EDO05196.1 - 4.4e-05 23.1 0.2 0.00011 21.9 0.2 1.7 1 0 0 1 1 1 1 E2 binding domain NAD_binding_7 PF13241.1 EDO05196.1 - 0.001 19.2 5.1 0.0013 18.9 0.8 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding UBACT PF02134.16 EDO05196.1 - 0.009 15.5 3.8 0.022 14.3 2.6 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein DUF507 PF04368.8 EDO05196.1 - 0.02 14.5 1.1 0.02 14.5 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF507) UBA_e1_C PF09358.5 EDO05196.1 - 0.026 14.6 0.2 0.026 14.6 0.2 2.1 2 0 0 2 2 2 0 Ubiquitin-activating enzyme e1 C-terminal domain TrkA_N PF02254.13 EDO05196.1 - 0.44 10.5 4.4 0.22 11.5 1.0 2.1 2 1 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.22 EDO05196.1 - 0.93 9.9 3.4 1 9.8 0.3 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3546 PF12066.3 EDO05197.1 - 2e-16 59.9 5.2 3.6e-16 59.1 3.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 EDO05197.1 - 1.2e-06 27.9 0.1 3.2e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-met PF12874.2 EDO05197.1 - 0.11 12.7 0.4 0.36 11.1 0.3 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type ARS2 PF04959.8 EDO05197.1 - 0.15 12.2 3.8 0.45 10.6 2.6 1.8 1 1 0 1 1 1 0 Arsenite-resistance protein 2 zf-C2H2 PF00096.21 EDO05197.1 - 3.3 8.2 7.1 0.32 11.4 1.3 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Phage_DsbA PF11126.3 EDO05198.1 - 0.061 13.4 0.1 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulator DsbA CheR PF01739.13 EDO05200.1 - 0.04 13.2 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain VID27 PF08553.5 EDO05202.1 - 4.6e-05 21.8 10.3 5.8e-05 21.5 7.1 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein RRN3 PF05327.6 EDO05202.1 - 0.00034 18.8 4.2 0.00034 18.8 2.9 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Zip PF02535.17 EDO05202.1 - 0.00061 18.8 0.4 0.00094 18.2 0.3 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Ycf1 PF05758.7 EDO05202.1 - 0.0022 15.8 2.2 0.002 15.9 1.5 1.1 1 0 0 1 1 1 1 Ycf1 DUF1510 PF07423.6 EDO05202.1 - 0.0031 16.9 11.4 0.0031 16.9 7.9 1.5 2 0 0 2 2 1 1 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 EDO05202.1 - 0.006 15.6 6.5 0.0092 15.0 4.5 1.3 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF2722 PF10846.3 EDO05202.1 - 0.0075 15.3 1.4 0.0081 15.2 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Nop14 PF04147.7 EDO05202.1 - 0.015 13.2 15.3 0.019 12.8 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family AIF_C PF14721.1 EDO05202.1 - 0.016 15.4 1.4 0.032 14.4 1.0 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RNA_pol_Rpc4 PF05132.9 EDO05202.1 - 0.021 14.8 7.1 0.046 13.7 4.9 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 GAGA_bind PF06217.7 EDO05202.1 - 0.023 14.6 1.2 0.031 14.2 0.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 EDO05202.1 - 0.03 14.1 3.2 0.056 13.2 2.2 1.4 1 0 0 1 1 1 0 DDHD domain Pox_Ag35 PF03286.9 EDO05202.1 - 0.042 13.3 13.3 0.073 12.5 9.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Trypan_glycop_C PF10659.4 EDO05202.1 - 0.049 13.9 10.4 0.1 12.8 7.2 1.5 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain NARP1 PF12569.3 EDO05202.1 - 0.066 11.9 7.7 0.09 11.5 5.4 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CobT PF06213.7 EDO05202.1 - 0.07 12.2 14.0 0.12 11.5 9.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.7 EDO05202.1 - 0.12 11.0 1.4 0.17 10.6 1.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) EST1 PF10374.4 EDO05202.1 - 0.15 12.0 0.3 0.33 10.9 0.2 1.7 1 0 0 1 1 1 0 Telomerase activating protein Est1 Anoctamin PF04547.7 EDO05202.1 - 0.17 10.5 2.2 0.25 9.9 1.5 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel Peptidase_S49_N PF08496.5 EDO05202.1 - 0.22 11.3 5.6 0.37 10.5 3.9 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Fmp27 PF10344.4 EDO05202.1 - 0.26 8.8 5.4 0.86 7.2 3.7 1.7 2 0 0 2 2 2 0 Mitochondrial protein from FMP27 SMN PF06003.7 EDO05202.1 - 0.39 9.7 4.9 60 2.6 5.3 2.0 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Serinc PF03348.10 EDO05202.1 - 0.54 8.9 1.6 0.7 8.5 1.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) TEX19 PF15553.1 EDO05202.1 - 0.89 9.4 8.1 1.9 8.3 5.6 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF1682 PF07946.9 EDO05202.1 - 0.95 8.2 13.4 1.4 7.7 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TFIIF_alpha PF05793.7 EDO05202.1 - 1.2 7.4 23.7 1.8 6.8 16.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Tom37_C PF11801.3 EDO05202.1 - 1.5 8.6 7.7 2.8 7.7 5.3 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain Tim54 PF11711.3 EDO05202.1 - 1.6 7.2 9.5 2.3 6.7 6.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNase_H2_suC PF08615.6 EDO05202.1 - 1.6 8.5 7.5 3.4 7.5 4.9 1.5 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RNA_pol_3_Rpc31 PF11705.3 EDO05202.1 - 1.7 8.5 24.6 2.9 7.7 17.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.7 EDO05202.1 - 2.5 7.2 20.9 0.12 11.6 10.8 1.4 2 0 0 2 2 1 0 SDA1 TSA PF03249.8 EDO05202.1 - 2.5 6.5 5.6 3.4 6.1 3.9 1.1 1 0 0 1 1 1 0 Type specific antigen Vfa1 PF08432.5 EDO05202.1 - 2.6 8.0 16.1 4.6 7.2 11.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 YqfQ PF14181.1 EDO05202.1 - 4.1 7.4 17.3 9 6.3 12.0 1.5 1 0 0 1 1 1 0 YqfQ-like protein Sec62 PF03839.11 EDO05202.1 - 4.3 6.6 8.3 7 5.9 5.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 MIP-T3 PF10243.4 EDO05202.1 - 6.2 5.1 21.4 8.9 4.6 14.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Paf1 PF03985.8 EDO05202.1 - 7.6 5.1 22.7 13 4.4 15.8 1.3 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.9 EDO05202.1 - 9.4 4.1 19.0 13 3.6 13.2 1.1 1 0 0 1 1 1 0 CDC45-like protein ATP-synt_E PF05680.7 EDO05202.1 - 9.7 6.2 11.6 19 5.2 8.0 1.4 1 0 0 1 1 1 0 ATP synthase E chain DUF1049 PF06305.6 EDO05203.1 - 3.8 7.0 13.4 6.2 6.3 1.8 4.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Borrelia_lipo_2 PF06238.6 EDO05204.1 - 0.0068 16.4 0.3 0.019 15.0 0.2 1.7 1 0 0 1 1 1 1 Borrelia burgdorferi BBR25 lipoprotein DUF1049 PF06305.6 EDO05204.1 - 0.81 9.2 11.8 6 6.4 1.8 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) F-box-like_2 PF13013.1 EDO05205.1 - 3.5e-08 33.1 2.3 0.0019 17.9 0.1 2.8 1 1 2 3 3 3 3 F-box-like domain Band_7 PF01145.20 EDO05205.1 - 0.00048 20.0 0.0 2.5 7.9 0.0 3.0 1 1 2 3 3 3 2 SPFH domain / Band 7 family DUF1958 PF09211.5 EDO05205.1 - 0.031 14.3 0.0 0.096 12.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) F-box-like_2 PF13013.1 EDO05206.1 - 0.0053 16.4 0.0 0.008 15.8 0.0 1.2 1 0 0 1 1 1 1 F-box-like domain VESA1_N PF12785.2 EDO05207.1 - 2.4e-121 405.9 6.9 5.3e-120 401.5 1.1 3.6 3 1 1 4 4 4 2 Variant erythrocyte surface antigen-1 DUF1664 PF07889.7 EDO05207.1 - 0.033 14.0 0.4 6.5 6.5 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) F-box-like_2 PF13013.1 EDO05209.1 - 1.2e-05 25.0 0.1 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like domain F-box-like_2 PF13013.1 EDO05210.1 - 0.00049 19.7 0.8 0.002 17.8 0.1 2.2 2 1 1 3 3 3 2 F-box-like domain DUF2076 PF09849.4 EDO05210.1 - 0.096 12.7 0.2 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) F-box-like_2 PF13013.1 EDO05211.1 - 2.2e-06 27.3 0.0 5.9e-05 22.7 0.0 2.3 1 1 2 3 3 3 2 F-box-like domain VESA1_N PF12785.2 EDO05212.1 - 7.2e-11 41.7 0.1 8.3e-11 41.5 0.1 1.0 1 0 0 1 1 1 1 Variant erythrocyte surface antigen-1 DUF4231 PF14015.1 EDO05214.1 - 0.0054 16.7 0.2 0.0093 15.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) Fumarate_red_D PF02313.12 EDO05214.1 - 0.022 14.6 1.0 0.4 10.5 0.0 2.2 2 0 0 2 2 2 0 Fumarate reductase subunit D DUF2207 PF09972.4 EDO05214.1 - 0.093 11.2 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CRPA PF05745.6 EDO05214.1 - 0.14 11.9 1.9 0.17 11.6 0.7 1.5 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF4199 PF13858.1 EDO05214.1 - 0.23 11.3 1.8 0.32 10.9 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF1469 PF07332.6 EDO05214.1 - 2.6 7.7 10.8 0.41 10.3 4.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF1980 PF09323.5 EDO05215.1 - 0.043 13.5 1.2 3.5 7.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) OppC_N PF12911.2 EDO05215.1 - 0.48 9.8 8.7 11 5.4 0.1 3.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C ODV-E18 PF10717.4 EDO05215.1 - 0.84 9.1 7.3 12 5.4 0.1 3.5 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Baculo_11_kDa PF06143.6 EDO05215.1 - 3.1 7.2 10.3 7.9 5.9 1.7 3.2 3 0 0 3 3 3 0 Baculovirus 11 kDa family VESA1_N PF12785.2 EDO05216.1 - 8e-14 51.4 12.0 2.5e-11 43.2 5.2 2.1 1 1 1 2 2 2 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05217.1 - 1.8e-214 712.9 17.0 1.8e-214 712.9 11.8 2.1 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05218.1 - 3e-08 33.1 3.6 7.9e-08 31.6 0.2 2.0 1 1 1 2 2 2 2 Variant erythrocyte surface antigen-1 CBF_beta PF02312.12 EDO05218.1 - 0.1 12.2 0.1 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 Core binding factor beta subunit EphA2_TM PF14575.1 EDO05219.1 - 0.23 11.8 3.6 6.1 7.3 0.2 2.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SPC25 PF06703.6 EDO05219.1 - 1.7 8.2 4.9 5.2 6.6 0.0 2.5 1 1 2 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4083 PF13314.1 EDO05219.1 - 4.6 7.1 9.2 15 5.4 0.7 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) PGG PF13962.1 EDO05219.1 - 5.2 6.7 12.3 3.2 7.3 1.1 2.9 2 1 1 3 3 3 0 Domain of unknown function DUF2207 PF09972.4 EDO05220.1 - 0.0009 17.9 0.1 0.0011 17.7 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) EpsG PF14897.1 EDO05220.1 - 0.015 14.2 1.0 0.022 13.6 0.7 1.2 1 0 0 1 1 1 0 EpsG family STT3 PF02516.9 EDO05220.1 - 0.017 14.1 0.9 0.027 13.4 0.6 1.3 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit TMCO5 PF14992.1 EDO05220.1 - 0.069 12.2 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 TMCO5 family DUF4191 PF13829.1 EDO05220.1 - 0.11 11.5 0.1 0.19 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF4519 PF15012.1 EDO05220.1 - 0.14 12.1 0.9 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) 7TM-7TMR_HD PF07698.6 EDO05220.1 - 0.28 10.6 4.9 0.038 13.4 0.8 1.4 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Potass_KdpF PF09604.5 EDO05220.1 - 2.4 8.0 5.2 5 7.0 0.1 2.4 2 0 0 2 2 2 0 F subunit of K+-transporting ATPase (Potass_KdpF) DUF1469 PF07332.6 EDO05223.1 - 0.0036 17.0 0.1 0.0056 16.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) OppC_N PF12911.2 EDO05223.1 - 0.035 13.4 0.5 0.035 13.4 0.4 2.2 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Na_H_Exchanger PF00999.16 EDO05223.1 - 0.043 12.3 0.7 0.07 11.6 0.5 1.4 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family TatC PF00902.13 EDO05223.1 - 0.056 12.8 0.1 2.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) SepZ PF06066.6 EDO05223.1 - 0.096 12.6 0.3 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 SepZ DUF4199 PF13858.1 EDO05223.1 - 0.097 12.5 0.4 0.16 11.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) P12 PF12669.2 EDO05223.1 - 0.099 12.8 6.3 1.9 8.7 0.3 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family DUF2207 PF09972.4 EDO05223.1 - 0.15 10.6 0.6 0.15 10.5 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) UPF0104 PF03706.8 EDO05223.1 - 0.17 11.1 1.3 0.21 10.8 0.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) O-antigen_lig PF13425.1 EDO05223.1 - 0.52 10.2 6.3 4.1 7.3 4.1 2.0 1 1 1 2 2 2 0 O-antigen ligase like membrane protein ABC2_membrane_5 PF13346.1 EDO05223.1 - 0.6 9.3 5.3 0.34 10.1 2.4 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Imm10 PF15562.1 EDO05223.1 - 1.3 8.8 12.1 0.34 10.7 0.4 3.1 3 0 0 3 3 3 0 Immunity protein 10 DUF1218 PF06749.7 EDO05224.1 - 0.055 13.9 0.8 0.24 11.8 0.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) CoA_binding_3 PF13727.1 EDO05224.1 - 0.31 10.8 5.3 0.21 11.4 0.4 2.4 2 0 0 2 2 2 0 CoA-binding domain VESA1_N PF12785.2 EDO05225.1 - 1.6e-20 73.5 9.2 2.7e-11 43.1 0.0 5.4 4 2 2 6 6 6 3 Variant erythrocyte surface antigen-1 F-box-like_2 PF13013.1 EDO05226.1 - 8.7e-08 31.8 0.0 0.14 11.9 0.0 3.7 1 1 3 4 4 4 4 F-box-like domain VESA1_N PF12785.2 EDO05227.1 - 4.7e-218 724.7 18.8 4.7e-218 724.7 13.0 3.3 4 0 0 4 4 4 1 Variant erythrocyte surface antigen-1 DDE_Tnp_1_assoc PF13808.1 EDO05227.1 - 0.065 12.9 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 DDE_Tnp_1-associated ALIX_LYPXL_bnd PF13949.1 EDO05227.1 - 0.09 11.7 0.0 0.25 10.2 0.0 1.7 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV FlaC_arch PF05377.6 EDO05227.1 - 0.11 12.4 0.1 0.41 10.5 0.1 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 EDO05227.1 - 1 7.9 2.3 9.6 4.7 0.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein VESA1_N PF12785.2 EDO05228.1 - 5.1e-203 675.1 21.8 5.1e-203 675.1 15.1 2.9 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 SSV1_ORF_D-335 PF07935.6 EDO05228.1 - 0.0094 15.6 0.1 0.058 13.1 0.0 2.4 2 0 0 2 2 2 1 ORF D-335-like protein ALIX_LYPXL_bnd PF13949.1 EDO05228.1 - 0.041 12.8 0.9 0.097 11.6 0.6 1.6 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF892 PF05974.7 EDO05228.1 - 0.75 9.5 4.2 0.46 10.2 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Baculo_PEP_C PF04513.7 EDO05228.1 - 1.1 9.0 6.1 0.58 9.9 0.6 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3829 PF12889.2 EDO05228.1 - 1.8 7.6 6.1 0.88 8.7 2.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3829) NPV_P10 PF05531.7 EDO05228.1 - 3 8.1 4.9 1 9.6 0.5 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4404 PF14357.1 EDO05228.1 - 5.2 7.5 4.7 21 5.6 0.5 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) RRM_1 PF00076.17 EDO05229.1 - 7e-15 54.4 0.0 1.4e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO05229.1 - 2.2e-09 37.1 0.0 4.5e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO05229.1 - 0.004 16.9 0.1 0.0092 15.8 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RAP PF08373.5 EDO05230.1 - 9e-14 51.0 0.2 2.5e-13 49.5 0.2 1.8 1 0 0 1 1 1 1 RAP domain Apis_Csd PF11671.3 EDO05230.1 - 0.035 13.9 0.0 0.035 13.9 0.0 1.9 2 0 0 2 2 2 0 Complementary sex determiner protein A_deaminase PF00962.17 EDO05231.1 - 4.2e-45 154.1 0.0 4.8e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Proteasome PF00227.21 EDO05232.1 - 2e-52 177.2 0.0 2.8e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO05232.1 - 1.1e-12 46.9 0.0 1.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature bPH_3 PF14470.1 EDO05232.1 - 0.063 13.5 0.1 0.34 11.2 0.0 2.1 2 1 1 3 3 3 0 Bacterial PH domain CLASP_N PF12348.3 EDO05233.1 - 0.0001 21.7 1.9 0.00017 21.0 1.3 1.4 1 0 0 1 1 1 1 CLASP N terminal Pox_VLTF3 PF04947.9 EDO05234.1 - 0.022 14.2 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Ribosomal_L33 PF00471.15 EDO05235.1 - 0.0061 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L33 Sad1_UNC PF07738.8 EDO05236.1 - 1e-13 51.2 0.3 2.1e-13 50.2 0.2 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Sec63 PF02889.11 EDO05237.1 - 7.1e-75 252.1 8.2 9.1e-47 159.7 1.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EDO05237.1 - 1.3e-50 171.1 1.9 1.1e-24 86.7 0.1 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EDO05237.1 - 3.1e-22 79.2 0.4 7e-10 39.0 0.0 3.1 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDO05237.1 - 6.7e-19 67.5 0.1 1.2e-08 34.6 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EDO05237.1 - 1.3e-08 35.0 3.1 0.0072 16.4 0.0 4.0 5 0 0 5 5 4 2 AAA domain PhoH PF02562.11 EDO05237.1 - 4.5e-07 29.3 0.0 0.02 14.1 0.1 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA PF00004.24 EDO05237.1 - 6.6e-07 29.6 0.5 0.039 14.1 0.2 3.6 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EDO05237.1 - 2.4e-05 23.9 0.0 0.17 11.6 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain T2SE PF00437.15 EDO05237.1 - 0.00012 21.1 0.0 0.36 9.7 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein IstB_IS21 PF01695.12 EDO05237.1 - 0.00021 20.7 0.2 0.61 9.4 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_11 PF13086.1 EDO05237.1 - 0.054 13.0 0.0 1.7 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EDO05237.1 - 0.084 13.1 0.1 0.74 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain CBFD_NFYB_HMF PF00808.18 EDO05238.1 - 5.9e-17 61.4 0.1 8.6e-17 60.9 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDO05238.1 - 1.9e-11 43.8 0.0 3.2e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EDO05238.1 - 0.17 11.8 0.3 0.41 10.6 0.1 1.6 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) Pkinase PF00069.20 EDO05240.1 - 2.4e-35 121.9 0.0 2.1e-18 66.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO05240.1 - 5.9e-13 48.4 0.0 1e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDO05240.1 - 0.0036 16.2 0.0 2.4 7.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EDO05240.1 - 0.086 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PPR_2 PF13041.1 EDO05244.1 - 7.2e-43 144.3 5.4 4.2e-11 42.6 0.0 6.8 4 1 2 6 6 6 5 PPR repeat family PPR PF01535.15 EDO05244.1 - 2.9e-25 86.4 8.8 1.9e-05 24.3 0.1 8.3 10 0 0 10 10 10 5 PPR repeat PPR_3 PF13812.1 EDO05244.1 - 8.8e-24 81.7 6.6 0.00026 21.0 0.0 9.3 10 0 0 10 10 10 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 EDO05244.1 - 1.4e-13 50.0 2.4 0.064 12.7 0.0 7.3 8 0 0 8 8 8 3 PPR repeat RPM2 PF08579.6 EDO05244.1 - 6.8e-05 22.9 0.2 1 9.4 0.0 4.7 3 2 2 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.6 EDO05244.1 - 0.00072 18.4 0.0 0.7 8.7 0.0 4.2 4 0 0 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway ATP13 PF12921.2 EDO05244.1 - 0.039 13.2 0.2 17 4.8 0.0 4.0 3 1 0 3 3 3 0 Mitochondrial ATPase expression DUF2686 PF10887.3 EDO05245.1 - 0.034 12.8 0.4 0.069 11.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) Zip PF02535.17 EDO05245.1 - 1.3 7.9 3.2 2 7.3 2.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3994 PF13159.1 EDO05245.1 - 2.6 8.3 10.6 0.095 12.9 2.2 2.3 2 2 0 2 2 2 0 Domain of unknown function (DUF3994) DUF663 PF04950.7 EDO05246.1 - 6.7e-73 245.2 0.0 8.7e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EDO05246.1 - 2.7e-18 65.3 0.0 5.7e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain CLAG PF03805.8 EDO05247.1 - 7.5e-17 60.0 0.1 2.6e-11 41.7 0.2 2.2 2 0 0 2 2 2 2 Cytoadherence-linked asexual protein DUF454 PF04304.8 EDO05247.1 - 0.073 13.1 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF454) DUF1376 PF07120.6 EDO05247.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) LRR_4 PF12799.2 EDO05248.1 - 2.6e-39 132.2 55.6 1.8e-11 43.3 2.2 6.2 4 1 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDO05248.1 - 3.5e-24 84.3 52.3 1.5e-08 34.2 6.2 4.2 2 1 3 5 5 5 5 Leucine rich repeat LRR_7 PF13504.1 EDO05248.1 - 1.7e-14 51.4 28.4 0.079 13.2 0.1 9.9 10 0 0 10 10 10 5 Leucine rich repeat LRR_1 PF00560.28 EDO05248.1 - 6.9e-12 43.6 40.6 0.066 13.2 0.1 9.3 9 1 0 9 9 9 7 Leucine Rich Repeat LRR_6 PF13516.1 EDO05248.1 - 2.7e-11 42.3 37.4 0.095 12.8 0.3 9.7 8 2 2 10 10 10 5 Leucine Rich repeat LRR_9 PF14580.1 EDO05248.1 - 1.2e-06 28.2 16.0 0.009 15.5 2.3 3.5 1 1 3 4 4 4 3 Leucine-rich repeat LRR_2 PF07723.8 EDO05248.1 - 4.6 7.8 13.0 2.2 8.9 0.2 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat GCV_T PF01571.16 EDO05249.1 - 2.8e-11 43.1 0.0 4.4e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain PhoPQ_related PF10142.4 EDO05251.1 - 0.11 10.9 0.0 0.26 9.7 0.0 1.5 1 1 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein DUF469 PF04320.9 EDO05252.1 - 0.028 15.1 0.3 0.56 11.0 0.1 2.4 2 1 0 2 2 2 0 Protein with unknown function (DUF469) HMG_box PF00505.14 EDO05252.1 - 0.053 13.7 1.6 6.8 7.0 0.1 2.7 2 0 0 2 2 2 0 HMG (high mobility group) box UvrD-helicase PF00580.16 EDO05252.1 - 0.092 12.0 2.3 0.12 11.6 1.6 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF2497 PF10691.4 EDO05252.1 - 2.1 8.3 4.8 14 5.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2497) GRIM-19 PF06212.7 EDO05253.1 - 0.1 12.2 0.1 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 GRIM-19 protein AAA PF00004.24 EDO05254.1 - 2.7e-21 76.1 0.0 1.5e-14 54.3 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDO05254.1 - 1.6e-12 47.7 0.3 8.3e-09 35.6 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EDO05254.1 - 4.7e-10 39.7 1.9 6.5e-06 26.3 0.1 4.4 4 1 0 4 4 2 1 AAA domain AAA_2 PF07724.9 EDO05254.1 - 9.3e-10 38.6 0.0 8.9e-06 25.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EDO05254.1 - 1.5e-08 34.4 0.6 0.0016 18.2 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EDO05254.1 - 4.5e-07 29.8 0.5 4.5e-06 26.5 0.2 2.7 2 1 0 2 2 1 1 Archaeal ATPase RuvB_N PF05496.7 EDO05254.1 - 6.4e-07 28.6 0.3 0.00029 19.9 0.1 2.9 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EDO05254.1 - 2.4e-06 27.0 0.1 6.6e-05 22.4 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_14 PF13173.1 EDO05254.1 - 2.4e-06 27.4 0.1 9.6e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain TniB PF05621.6 EDO05254.1 - 0.00036 19.3 0.2 0.05 12.3 0.0 2.7 3 0 0 3 3 3 1 Bacterial TniB protein AAA_17 PF13207.1 EDO05254.1 - 0.00044 21.0 0.1 0.18 12.6 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDO05254.1 - 0.00045 20.5 0.0 0.58 10.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EDO05254.1 - 0.00053 19.5 0.0 0.1 11.9 0.0 3.2 2 1 1 3 3 3 1 AAA-like domain DUF258 PF03193.11 EDO05254.1 - 0.00083 18.5 0.2 0.044 12.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EDO05254.1 - 0.0011 19.1 0.0 0.21 11.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 EDO05254.1 - 0.0013 18.4 0.0 0.027 14.1 0.0 2.9 3 0 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.16 EDO05254.1 - 0.0029 16.7 0.5 0.19 10.9 0.0 2.8 3 1 0 3 3 2 1 Magnesium chelatase, subunit ChlI Med4 PF10018.4 EDO05254.1 - 0.0062 15.9 0.2 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 IncA PF04156.9 EDO05254.1 - 0.0085 15.7 2.1 0.019 14.5 1.4 1.5 1 0 0 1 1 1 1 IncA protein AAA_19 PF13245.1 EDO05254.1 - 0.0094 15.6 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain DEAD PF00270.24 EDO05254.1 - 0.019 14.4 0.0 0.67 9.4 0.0 2.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.1 EDO05254.1 - 0.02 14.2 0.0 0.13 11.6 0.0 2.3 3 0 0 3 3 2 0 AAA domain Clp_N PF02861.15 EDO05254.1 - 0.033 14.1 0.0 0.32 10.9 0.0 2.5 2 0 0 2 2 2 0 Clp amino terminal domain NTPase_1 PF03266.10 EDO05254.1 - 0.044 13.4 0.2 2.8 7.6 0.0 3.6 4 0 0 4 4 4 0 NTPase Zeta_toxin PF06414.7 EDO05254.1 - 0.044 12.8 0.0 0.79 8.7 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.10 EDO05254.1 - 0.045 13.5 2.7 1.7 8.4 0.0 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Miro PF08477.8 EDO05254.1 - 0.056 13.9 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_33 PF13671.1 EDO05254.1 - 0.064 13.1 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EDO05254.1 - 0.074 13.1 0.2 0.51 10.3 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EDO05254.1 - 0.088 12.2 0.0 3 7.2 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain MMR_HSR1 PF01926.18 EDO05254.1 - 0.11 12.4 0.7 1.5 8.8 0.0 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EDO05254.1 - 0.11 12.4 0.0 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EDO05254.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArgK PF03308.11 EDO05254.1 - 0.12 11.1 0.0 0.59 8.8 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_29 PF13555.1 EDO05254.1 - 0.13 11.7 0.0 0.5 9.9 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain SlyX PF04102.7 EDO05254.1 - 0.27 11.6 2.7 13 6.1 0.9 2.7 2 0 0 2 2 2 0 SlyX CDC37_N PF03234.9 EDO05255.1 - 9.5e-06 26.0 2.6 9.5e-06 26.0 1.8 1.8 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding DUF4550 PF15084.1 EDO05255.1 - 2.5 8.2 5.6 1.2 9.3 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4550) V-SNARE_C PF12352.3 EDO05256.1 - 2.8e-07 30.5 6.2 5e-07 29.6 1.3 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DASH_Duo1 PF08651.5 EDO05256.1 - 0.00042 19.8 7.9 0.099 12.2 0.2 2.7 2 0 0 2 2 2 2 DASH complex subunit Duo1 SIMPL PF04402.9 EDO05256.1 - 0.075 12.8 1.9 0.1 12.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Phospholamban PF04272.9 EDO05256.1 - 0.11 11.9 3.0 0.35 10.3 2.1 1.8 1 0 0 1 1 1 0 Phospholamban NPV_P10 PF05531.7 EDO05256.1 - 0.13 12.5 10.0 1.4 9.2 0.9 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DP PF08781.5 EDO05256.1 - 0.14 11.8 7.2 0.052 13.2 3.1 1.7 2 0 0 2 2 2 0 Transcription factor DP DUF106 PF01956.11 EDO05256.1 - 0.17 11.3 4.5 19 4.7 3.2 2.2 1 1 0 1 1 1 0 Integral membrane protein DUF106 ApoC-I PF04691.7 EDO05256.1 - 0.19 11.4 7.7 1 9.1 0.2 4.0 3 1 1 4 4 4 0 Apolipoprotein C-I (ApoC-1) TNV_CP PF03898.8 EDO05256.1 - 0.22 10.5 3.7 0.3 10.1 2.5 1.3 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein Flagellin_N PF00669.15 EDO05256.1 - 0.3 10.8 5.8 5.1 6.8 0.2 2.6 1 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region Homoserine_dh PF00742.14 EDO05256.1 - 0.84 9.2 4.0 1.4 8.5 2.8 1.3 1 1 0 1 1 1 0 Homoserine dehydrogenase Tweety PF04906.8 EDO05256.1 - 0.85 7.9 10.8 0.34 9.2 1.0 2.1 1 1 0 2 2 2 0 Tweety L31 PF09784.4 EDO05256.1 - 1.1 9.3 3.5 17 5.5 0.3 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 V-SNARE PF05008.10 EDO05256.1 - 2.7 8.2 12.0 2.9 8.1 4.4 2.7 2 2 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF4140 PF13600.1 EDO05256.1 - 4.4 7.7 10.0 1.1 9.7 1.5 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Plasmid_RAQPRD PF09686.5 EDO05256.1 - 4.5 7.4 5.4 13 5.9 0.1 3.0 3 0 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF1664 PF07889.7 EDO05256.1 - 6.9 6.4 7.2 4.2 7.1 0.4 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.6 EDO05256.1 - 8.8 5.5 9.0 7.5 5.7 1.8 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein AdoHcyase PF05221.12 EDO05258.1 - 7.4e-85 284.1 0.0 8.6e-85 283.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EDO05258.1 - 1.8e-60 203.4 0.8 2.7e-60 202.9 0.6 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EDO05258.1 - 4.5e-10 38.9 0.4 8.1e-10 38.1 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EDO05258.1 - 1.5e-06 27.6 0.3 2.3e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EDO05258.1 - 0.00034 20.5 0.3 0.00071 19.5 0.2 1.6 1 1 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 EDO05258.1 - 0.0053 16.4 0.4 0.0091 15.6 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EDO05258.1 - 0.007 16.4 0.5 0.015 15.3 0.4 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EDO05258.1 - 0.0098 16.1 0.2 0.019 15.2 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EDO05258.1 - 0.013 15.1 1.0 0.029 13.9 0.7 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.12 EDO05258.1 - 0.022 15.1 0.1 0.05 14.0 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.14 EDO05258.1 - 0.023 13.7 0.1 0.16 11.0 0.1 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ELFV_dehydrog PF00208.16 EDO05258.1 - 0.95 8.9 3.5 2.7 7.5 2.4 1.7 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF3698 PF12479.3 EDO05260.1 - 0.017 15.2 0.2 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) Phasin PF05597.6 EDO05261.1 - 0.031 14.0 4.7 0.031 14.0 1.2 2.1 1 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Gp-FAR-1 PF05823.7 EDO05261.1 - 0.12 12.3 2.5 0.11 12.4 0.8 1.7 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PMEI PF04043.10 EDO05261.1 - 0.54 10.1 3.9 0.46 10.3 1.7 1.6 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DegS PF05384.6 EDO05261.1 - 0.64 9.2 10.2 2 7.6 7.1 1.7 1 1 0 1 1 1 0 Sensor protein DegS GWT1 PF06423.7 EDO05262.1 - 0.0065 16.5 0.4 0.014 15.5 0.0 1.7 2 0 0 2 2 2 1 GWT1 UPF0233 PF06781.7 EDO05262.1 - 0.17 11.5 0.5 0.46 10.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) eIF3_subunit PF08597.5 EDO05263.1 - 4.2e-09 36.3 4.2 4.2e-09 36.3 2.9 1.9 1 1 1 2 2 2 1 Translation initiation factor eIF3 subunit PPV_E1_N PF00524.13 EDO05263.1 - 0.13 12.4 3.9 0.54 10.4 1.0 2.4 2 0 0 2 2 2 0 E1 Protein, N terminal domain YqzH PF14164.1 EDO05263.1 - 1 9.3 4.9 4.3 7.3 0.0 3.1 4 0 0 4 4 4 0 YqzH-like protein Corona_M PF01635.13 EDO05264.1 - 1.3 7.8 9.0 1.2 7.9 3.9 2.0 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein MgtE PF01769.11 EDO05264.1 - 1.6 9.0 7.3 0.75 10.0 2.8 2.1 2 1 0 2 2 2 0 Divalent cation transporter Histone PF00125.19 EDO05265.1 - 8e-34 115.6 0.5 1.3e-33 114.9 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDO05265.1 - 6.3e-05 23.0 0.0 9.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDO05265.1 - 0.0057 16.6 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EDO05265.1 - 0.04 13.6 0.1 0.091 12.5 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit RRM_6 PF14259.1 EDO05266.1 - 0.017 15.0 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Propep_M14 PF02244.11 EDO05266.1 - 0.09 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase activation peptide eIF3_subunit PF08597.5 EDO05267.1 - 4.2e-09 36.3 4.2 4.2e-09 36.3 2.9 1.9 1 1 1 2 2 2 1 Translation initiation factor eIF3 subunit PPV_E1_N PF00524.13 EDO05267.1 - 0.13 12.4 3.9 0.54 10.4 1.0 2.4 2 0 0 2 2 2 0 E1 Protein, N terminal domain YqzH PF14164.1 EDO05267.1 - 1 9.3 4.9 4.3 7.3 0.0 3.1 4 0 0 4 4 4 0 YqzH-like protein Histone PF00125.19 EDO05270.1 - 8e-34 115.6 0.5 1.3e-33 114.9 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDO05270.1 - 6.3e-05 23.0 0.0 9.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDO05270.1 - 0.0057 16.6 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EDO05270.1 - 0.04 13.6 0.1 0.091 12.5 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DUF2443 PF10398.4 EDO05271.1 - 0.21 11.3 7.7 5.1 6.9 0.1 4.3 4 1 0 4 4 4 0 Protein of unknown function (DUF2443) DUF848 PF05852.6 EDO05271.1 - 3.7 7.3 51.0 0.3 10.9 3.7 5.5 2 1 4 6 6 6 0 Gammaherpesvirus protein of unknown function (DUF848) Adaptin_N PF01602.15 EDO05272.1 - 3.9e-40 137.6 1.6 4.9e-40 137.3 1.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EDO05272.1 - 2.9e-06 27.4 0.0 0.014 15.6 0.0 4.0 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.17 EDO05272.1 - 0.0021 18.0 1.2 0.051 13.6 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.2 EDO05272.1 - 0.0049 16.7 1.3 0.26 11.1 0.1 3.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.7 EDO05272.1 - 0.015 15.0 2.5 3.8 7.1 0.0 3.5 1 1 1 3 3 3 0 rRNA processing/ribosome biogenesis Arm PF00514.18 EDO05272.1 - 0.046 13.5 0.0 0.39 10.6 0.0 2.8 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Synaptobrevin PF00957.16 EDO05274.1 - 8.7e-11 41.2 0.0 1.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EDO05274.1 - 0.00082 18.8 0.0 0.0023 17.4 0.0 1.7 1 1 1 2 2 2 1 Regulated-SNARE-like domain AAA_12 PF13087.1 EDO05275.1 - 2.1e-30 105.6 0.0 4.1e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EDO05275.1 - 2e-23 83.2 0.0 1.7e-22 80.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO05275.1 - 5.6e-06 26.0 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EDO05275.1 - 6e-05 22.6 0.4 0.026 14.0 0.0 4.0 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EDO05275.1 - 0.00011 21.8 0.0 0.54 9.8 0.0 2.6 3 0 0 3 3 3 2 AAA domain UvrD_C_2 PF13538.1 EDO05275.1 - 0.0034 17.4 0.0 0.0078 16.3 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 EDO05275.1 - 0.01 15.2 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDO05275.1 - 0.04 13.6 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDO05275.1 - 0.06 13.4 0.0 0.48 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EDO05275.1 - 0.061 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EDO05275.1 - 0.2 10.6 0.6 0.33 9.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ArsA_ATPase PF02374.10 EDO05277.1 - 8.1e-85 284.5 4.0 1.2e-79 267.6 0.6 2.2 1 1 1 2 2 2 2 Anion-transporting ATPase CbiA PF01656.18 EDO05277.1 - 3e-14 52.8 0.2 6.3e-14 51.8 0.1 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EDO05277.1 - 7.8e-09 35.6 0.0 5.8e-08 32.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EDO05277.1 - 0.00021 20.5 0.0 0.00048 19.3 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.17 EDO05277.1 - 0.0003 19.7 0.1 0.00078 18.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain SRP54 PF00448.17 EDO05277.1 - 0.00096 18.6 0.2 0.035 13.5 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 EDO05277.1 - 0.0017 17.7 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 YhjQ protein DEAD PF00270.24 EDO05277.1 - 0.0034 16.8 0.0 0.0071 15.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase NACHT PF05729.7 EDO05277.1 - 0.0051 16.4 0.6 0.033 13.8 0.2 2.4 2 1 0 2 2 2 1 NACHT domain PIF1 PF05970.9 EDO05277.1 - 0.0055 15.6 0.2 0.022 13.6 0.0 2.0 2 1 1 3 3 3 1 PIF1-like helicase AAA_25 PF13481.1 EDO05277.1 - 0.0074 15.7 0.1 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EDO05277.1 - 0.0085 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 ATPase MipZ AAA_16 PF13191.1 EDO05277.1 - 0.0087 16.0 0.1 0.025 14.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EDO05277.1 - 0.019 14.0 0.0 0.042 12.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EDO05277.1 - 0.021 15.6 0.1 0.21 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EDO05277.1 - 0.029 13.7 0.1 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.22 EDO05277.1 - 0.038 14.3 0.2 0.14 12.4 0.0 2.0 2 1 0 2 2 2 0 ABC transporter APS_kinase PF01583.15 EDO05277.1 - 0.04 13.5 0.1 0.23 11.1 0.1 2.2 1 1 1 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EDO05277.1 - 0.093 12.9 0.1 0.62 10.2 0.0 2.4 2 1 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 EDO05277.1 - 0.094 12.4 0.1 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EDO05277.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EDO05277.1 - 0.12 12.0 0.2 0.32 10.6 0.1 1.7 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.12 EDO05277.1 - 0.32 10.4 2.8 0.4 10.1 0.2 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EDO05277.1 - 0.62 10.3 3.9 0.49 10.7 0.3 2.5 2 2 0 2 2 2 0 AAA domain Arm PF00514.18 EDO05278.1 - 1.4e-09 37.4 0.0 0.00051 19.7 0.0 4.4 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EDO05278.1 - 0.0009 19.4 0.7 0.71 10.2 0.0 2.7 1 1 0 2 2 2 2 HEAT repeats Pkinase PF00069.20 EDO05279.1 - 1.6e-64 217.6 0.0 2.4e-64 216.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO05279.1 - 1.1e-27 96.7 0.0 1.7e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO05279.1 - 0.0099 14.8 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Cortex-I_coil PF09304.5 EDO05280.1 - 0.19 11.7 7.6 0.48 10.4 2.0 2.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil tRNA-synt_1g PF09334.6 EDO05281.1 - 3.3e-97 325.5 0.0 1.5e-95 320.1 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EDO05281.1 - 2.9e-30 104.8 0.3 2.1e-19 69.0 0.1 3.9 2 1 2 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EDO05281.1 - 2.4e-10 40.0 0.0 1.9e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EDO05281.1 - 4.6e-07 28.8 0.0 0.00033 19.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1d PF00750.14 EDO05281.1 - 0.047 12.5 0.1 0.89 8.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 EDO05281.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Amidohydro_5 PF13594.1 EDO05283.1 - 0.036 13.9 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase MMR_HSR1 PF01926.18 EDO05284.1 - 1.1e-18 67.2 0.0 4e-18 65.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDO05284.1 - 1.5e-05 24.5 0.1 0.0012 18.2 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EDO05284.1 - 1.5e-05 24.8 0.0 0.0077 16.0 0.0 2.3 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.13 EDO05284.1 - 5.4e-05 22.5 0.0 8e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3625 PF12293.3 EDO05284.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3625) ABC_tran PF00005.22 EDO05284.1 - 0.094 13.0 0.0 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 ABC transporter LAGLIDADG_3 PF14528.1 EDO05284.1 - 0.095 12.9 0.1 0.53 10.5 0.0 2.1 2 0 0 2 2 2 0 LAGLIDADG-like domain Evr1_Alr PF04777.8 EDO05285.1 - 7.8e-10 38.5 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family CRAL_TRIO PF00650.15 EDO05286.1 - 5.9e-35 120.1 0.0 9.9e-35 119.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EDO05286.1 - 4.8e-09 36.2 0.0 7.3e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF4309 PF14172.1 EDO05286.1 - 0.14 12.1 0.2 15 5.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4309) TFIIS_M PF07500.9 EDO05288.1 - 4.9e-19 68.4 0.9 1e-18 67.4 0.6 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain E1_dh PF00676.15 EDO05290.1 - 3.9e-51 173.5 0.0 5.9e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.19 EDO05290.1 - 1.3e-50 171.3 0.0 2.1e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DUF2815 PF10991.3 EDO05292.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) HEAT_2 PF13646.1 EDO05294.1 - 0.0001 22.5 0.0 0.00052 20.2 0.0 2.1 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.17 EDO05294.1 - 0.0021 17.9 0.0 8.7 6.7 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat NolV PF06635.7 EDO05294.1 - 0.092 11.9 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein NolV Trp_Tyr_perm PF03222.8 EDO05295.1 - 0.00011 21.1 11.3 0.0013 17.6 0.7 2.5 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family Aa_trans PF01490.13 EDO05295.1 - 0.00062 18.3 17.4 0.0031 16.0 12.1 2.1 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Arf PF00025.16 EDO05297.1 - 1.5e-67 226.2 0.3 1.7e-67 226.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EDO05297.1 - 7.5e-10 38.0 2.8 3.2e-06 26.0 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDO05297.1 - 1.4e-09 37.4 0.0 1.6e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EDO05297.1 - 1.2e-08 34.3 0.0 1.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EDO05297.1 - 1.3e-08 34.7 0.0 1.7e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EDO05297.1 - 5.9e-08 32.2 0.0 6.9e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO05297.1 - 1.3e-06 28.9 0.0 1.8e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EDO05297.1 - 3.7e-05 23.2 0.0 0.0013 18.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EDO05297.1 - 0.0074 16.5 0.4 0.022 15.0 0.2 1.7 1 1 0 1 1 1 1 ABC transporter PduV-EutP PF10662.4 EDO05297.1 - 0.018 14.5 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EDO05297.1 - 0.043 13.2 0.1 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EDO05297.1 - 0.1 12.4 0.0 1.6 8.4 0.0 2.1 1 1 1 2 2 2 0 Dynamin family Tbf5 PF06331.7 EDO05298.1 - 5.5e-23 80.5 0.1 6.2e-23 80.3 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 SDA1 PF05285.7 EDO05299.1 - 7.3e-21 74.7 41.2 3.1e-15 56.2 8.2 2.8 2 1 1 3 3 3 2 SDA1 Cnd2 PF05786.9 EDO05300.1 - 2.6e-31 108.9 0.0 9.4e-21 74.0 0.1 3.0 2 1 0 2 2 2 2 Condensin complex subunit 2 DUF2271 PF10029.4 EDO05300.1 - 0.2 11.1 0.1 0.39 10.1 0.1 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) Pyr_redox_2 PF07992.9 EDO05301.1 - 8.2e-31 107.4 0.0 1.5e-30 106.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EDO05301.1 - 2.3e-24 85.5 0.0 6e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EDO05301.1 - 1.1e-18 67.3 1.4 6.7e-14 52.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO05301.1 - 7.1e-10 39.2 0.0 1.6e-08 34.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDO05301.1 - 1.5e-06 27.6 0.6 2.5e-06 26.8 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EDO05301.1 - 2.8e-06 26.4 0.7 9.8e-06 24.6 0.2 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EDO05301.1 - 4.5e-06 25.7 0.5 1.7e-05 23.8 0.0 2.2 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EDO05301.1 - 1.8e-05 24.6 4.9 0.00032 20.6 0.2 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDO05301.1 - 0.00047 19.1 2.9 0.0005 19.0 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EDO05301.1 - 0.00056 18.5 0.2 0.0013 17.2 0.1 1.7 1 0 0 1 1 1 1 HI0933-like protein K_oxygenase PF13434.1 EDO05301.1 - 0.0029 16.5 0.0 0.032 13.1 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EDO05301.1 - 0.0041 16.2 0.1 0.008 15.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 EDO05301.1 - 0.016 14.7 0.7 0.03 13.8 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EDO05301.1 - 0.13 12.0 0.0 6.7 6.4 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EDO05301.1 - 0.27 10.2 1.4 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain LMF1 PF06762.9 EDO05302.1 - 1.4e-38 132.7 0.3 2.4e-38 131.9 0.2 1.4 1 0 0 1 1 1 1 Lipase maturation factor Sec1 PF00995.18 EDO05303.1 - 5.8e-87 292.6 0.0 7e-87 292.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Ribosomal_L18p PF00861.17 EDO05306.1 - 1.2e-19 70.6 2.7 1.3e-18 67.2 1.8 2.0 1 1 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_S13 PF00416.17 EDO05308.1 - 0.027 14.9 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S13/S18 zf-RING_2 PF13639.1 EDO05309.1 - 2.9e-09 36.6 8.6 2.9e-09 36.6 6.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EDO05309.1 - 4e-07 30.0 5.6 1.1e-06 28.6 3.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EDO05309.1 - 4.2e-06 26.3 7.2 9.5e-06 25.1 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO05309.1 - 1e-05 25.1 9.8 2.6e-05 23.8 6.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDO05309.1 - 2.4e-05 23.8 8.8 5.8e-05 22.6 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO05309.1 - 9.3e-05 22.3 9.1 0.00026 20.9 6.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO05309.1 - 0.00013 21.5 2.8 0.0003 20.4 2.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EDO05309.1 - 0.00036 20.3 3.8 0.001 18.8 2.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EDO05309.1 - 0.55 9.8 8.5 1.5 8.4 5.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EDO05309.1 - 0.96 9.1 9.8 2.4 7.9 6.8 1.7 1 0 0 1 1 1 0 PHD-finger DUF2053 PF09767.4 EDO05310.1 - 2.6e-17 63.2 3.6 3.1e-17 63.0 2.5 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) PrsW-protease PF13367.1 EDO05310.1 - 0.00051 19.2 0.5 0.00069 18.8 0.4 1.4 1 1 0 1 1 1 1 Protease prsW family Na_Pi_cotrans PF02690.10 EDO05310.1 - 0.008 15.8 1.7 0.036 13.7 0.4 2.1 1 1 1 2 2 2 1 Na+/Pi-cotransporter DUF4131 PF13567.1 EDO05310.1 - 0.45 9.8 2.5 0.72 9.2 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DJ-1_PfpI PF01965.19 EDO05311.1 - 1.2e-23 83.2 2.3 1.6e-23 82.7 1.6 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EDO05311.1 - 5.6e-13 48.4 0.4 7e-13 48.1 0.3 1.1 1 0 0 1 1 1 1 Putative amidotransferase NMO PF03060.10 EDO05311.1 - 0.0014 17.8 1.8 0.0018 17.5 1.3 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase CRAL_TRIO_2 PF13716.1 EDO05312.1 - 4.1e-24 85.1 0.5 8.1e-24 84.2 0.4 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EDO05312.1 - 3.6e-08 33.1 0.0 6.3e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 EDO05312.1 - 0.029 13.1 0.0 0.059 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Filamin PF00630.14 EDO05313.1 - 1e-05 25.9 0.0 0.046 14.2 0.0 2.5 2 0 0 2 2 2 2 Filamin/ABP280 repeat bZIP_Maf PF03131.12 EDO05313.1 - 1 9.7 3.5 0.65 10.3 0.6 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor AP2 PF00847.15 EDO05314.1 - 4.5e-07 29.9 1.0 4.5e-07 29.9 0.7 2.0 2 0 0 2 2 2 1 AP2 domain Flavodoxin_1 PF00258.20 EDO05315.1 - 4.1e-26 91.6 0.0 7.5e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EDO05315.1 - 3.5e-16 59.7 0.0 1.5e-15 57.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.15 EDO05315.1 - 2.1e-14 53.5 0.1 3.9e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_6 PF00970.19 EDO05315.1 - 0.0079 16.2 0.1 0.052 13.6 0.0 2.3 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain Chordopox_G3 PF06129.7 EDO05315.1 - 0.64 10.1 5.4 4.3 7.5 1.1 2.8 2 0 0 2 2 2 0 Chordopoxvirus G3 protein PAPS_reduct PF01507.14 EDO05316.1 - 5.3e-17 62.1 0.0 7.1e-11 42.2 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.17 EDO05317.1 - 3.4e-16 58.6 0.0 5.5e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO05317.1 - 1.3e-14 53.8 0.0 2.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO05317.1 - 4.1e-08 32.9 0.1 7.3e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CKS PF01111.14 EDO05318.1 - 6.4e-23 80.3 0.1 1e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit BPL_LplA_LipB PF03099.14 EDO05319.1 - 0.00035 20.5 0.0 0.00093 19.2 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Collagen_bind PF05737.7 EDO05319.1 - 0.084 13.0 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Collagen binding domain DUF572 PF04502.8 EDO05321.1 - 7.5e-49 166.6 4.8 8.8e-49 166.4 3.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) NACHT PF05729.7 EDO05321.1 - 0.14 11.8 0.1 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain tRNA-synt_1e PF01406.14 EDO05322.1 - 5.4e-118 393.5 0.0 7.9e-118 392.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EDO05322.1 - 2.2e-10 39.7 0.2 0.00026 19.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EDO05322.1 - 0.00019 19.5 0.0 0.00034 18.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.16 EDO05322.1 - 0.034 12.8 0.1 0.11 11.0 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Upf2 PF04050.9 EDO05324.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DUF2975 PF11188.3 EDO05325.1 - 0.0059 16.3 0.4 0.0063 16.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) DUF2101 PF09874.4 EDO05325.1 - 0.04 13.3 0.2 0.041 13.3 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) DUF2393 PF09624.5 EDO05325.1 - 0.061 12.8 0.6 0.06 12.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DUF2077 PF09850.4 EDO05325.1 - 0.11 11.9 0.8 0.13 11.6 0.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) FtsH_ext PF06480.10 EDO05325.1 - 0.16 12.1 0.6 0.19 11.9 0.4 1.2 1 0 0 1 1 1 0 FtsH Extracellular 4HBT PF03061.17 EDO05329.1 - 1.4e-06 28.3 0.3 5.1e-06 26.5 0.2 1.9 1 1 0 1 1 1 1 Thioesterase superfamily CHCH PF06747.8 EDO05332.1 - 0.0021 17.9 0.1 0.0055 16.5 0.1 1.7 1 0 0 1 1 1 1 CHCH domain Urb2 PF10441.4 EDO05332.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Urb2/Npa2 family Pet191_N PF10203.4 EDO05332.1 - 0.078 13.0 1.2 0.16 12.0 0.5 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Plant_tran PF04827.9 EDO05332.1 - 0.12 11.7 0.1 14 5.0 0.0 2.1 2 0 0 2 2 2 0 Plant transposon protein CS PF04969.11 EDO05333.1 - 6.4e-17 61.8 0.6 9.4e-17 61.3 0.4 1.2 1 0 0 1 1 1 1 CS domain HSP20 PF00011.16 EDO05333.1 - 0.081 12.7 0.2 0.29 10.9 0.1 1.9 1 1 1 2 2 2 0 Hsp20/alpha crystallin family DUF3449 PF11931.3 EDO05335.1 - 1.2e-79 266.4 3.0 1.2e-79 266.4 2.1 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EDO05335.1 - 5e-11 41.9 3.1 1.7e-10 40.2 0.6 2.8 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain RepA_C PF04796.7 EDO05335.1 - 0.041 13.4 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 Plasmid encoded RepA protein zf-met PF12874.2 EDO05335.1 - 0.1 12.8 0.7 0.37 11.0 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Desulfoferrod_N PF06397.7 EDO05335.1 - 0.21 11.0 0.9 0.4 10.1 0.6 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Fumerase PF05681.9 EDO05336.1 - 9e-89 297.1 0.0 1.2e-88 296.7 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 EDO05336.1 - 5.2e-75 251.0 0.0 9.4e-75 250.2 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus IBN_N PF03810.14 EDO05336.1 - 0.014 15.2 0.1 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Importin-beta N-terminal domain EST1 PF10374.4 EDO05338.1 - 0.041 13.8 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 Telomerase activating protein Est1 G-patch_2 PF12656.2 EDO05339.1 - 5.1e-15 55.0 0.0 1.1e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 DExH-box splicing factor binding site Lipin_N PF04571.9 EDO05339.1 - 0.046 13.3 2.8 0.33 10.6 0.1 2.3 1 1 0 2 2 2 0 lipin, N-terminal conserved region GCS PF03074.11 EDO05340.1 - 4.1e-85 286.0 1.1 5.7e-85 285.6 0.7 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase 2OG-FeII_Oxy_2 PF13532.1 EDO05341.1 - 1.7e-23 83.4 0.0 2.4e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RNA_pol_A_bac PF01000.21 EDO05342.1 - 3.7e-22 78.6 0.0 2e-21 76.2 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EDO05342.1 - 8e-16 56.9 0.0 1e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.1 EDO05342.1 - 0.059 12.8 0.2 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Dus PF01207.12 EDO05343.1 - 1.8e-56 191.2 0.0 2.2e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EDO05343.1 - 0.00021 20.6 0.0 0.0004 19.7 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF86 PF01934.12 EDO05344.1 - 0.036 13.6 1.7 2.6 7.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF86 Bin3 PF06859.7 EDO05344.1 - 0.048 13.6 0.8 0.071 13.0 0.6 1.3 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) POTRA_2 PF08479.6 EDO05344.1 - 0.083 12.5 1.3 6 6.6 0.0 2.4 2 0 0 2 2 2 0 POTRA domain, ShlB-type Fib_alpha PF08702.5 EDO05344.1 - 0.98 9.5 6.8 1.3 9.1 4.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Alpha-mann_mid PF09261.6 EDO05345.1 - 0.14 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Alpha mannosidase, middle domain CS PF04969.11 EDO05347.1 - 0.011 16.2 0.3 0.011 16.2 0.2 2.4 3 0 0 3 3 3 0 CS domain HD_5 PF13487.1 EDO05347.1 - 0.042 13.8 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 HD domain Siah-Interact_N PF09032.6 EDO05347.1 - 0.16 12.0 7.8 4.8 7.3 0.1 2.9 1 1 1 2 2 2 0 Siah interacting protein, N terminal Aminotran_5 PF00266.14 EDO05348.1 - 2.2e-85 286.6 0.0 4.6e-85 285.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EDO05348.1 - 2.9e-09 36.4 0.0 4.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EDO05348.1 - 2.8e-07 29.9 0.0 5.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EDO05348.1 - 0.12 10.7 0.0 0.19 10.1 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain GCD14 PF08704.5 EDO05349.1 - 0.33 10.3 3.2 0.5 9.8 2.2 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DNMT1-RFD PF12047.3 EDO05350.1 - 0.0014 18.3 0.0 0.0039 16.9 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain WHIM2 PF15613.1 EDO05350.1 - 0.0026 17.6 2.1 0.0086 15.9 1.5 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 DUF3738 PF12543.3 EDO05352.1 - 0.096 12.2 0.1 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) cwf18 PF08315.7 EDO05353.1 - 1.5e-16 61.0 2.3 1.9e-16 60.6 1.6 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Tn7_Tnp_TnsA_C PF08721.6 EDO05353.1 - 0.032 14.2 0.5 0.055 13.4 0.2 1.5 1 1 0 1 1 1 0 TnsA endonuclease C terminal Sec5 PF15469.1 EDO05353.1 - 0.067 12.9 1.0 0.085 12.5 0.7 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 Citrate_synt PF00285.16 EDO05353.1 - 0.11 11.2 0.1 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Citrate synthase Imm2 PF14426.1 EDO05353.1 - 0.44 10.5 2.1 1.3 9.1 0.5 2.3 2 0 0 2 2 2 0 Immunity protein Imm2 PA14 PF07691.7 EDO05354.1 - 3.5e-19 68.9 0.0 5.6e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain BNR_2 PF13088.1 EDO05355.1 - 0.0016 17.8 0.1 0.49 9.6 0.1 3.5 1 1 2 3 3 3 2 BNR repeat-like domain BNR PF02012.15 EDO05355.1 - 0.0039 16.7 12.7 1.8 8.7 0.0 7.5 8 0 0 8 8 8 2 BNR/Asp-box repeat DUF1982 PF09326.6 EDO05357.1 - 0.21 11.7 0.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1982) zf-CCCH PF00642.19 EDO05358.1 - 0.0061 16.2 0.8 0.0061 16.2 0.6 3.8 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) bZIP_C PF12498.3 EDO05358.1 - 0.5 11.6 4.5 1.1 10.5 3.1 1.5 1 0 0 1 1 1 0 Basic leucine-zipper C terminal zf-CCHC PF00098.18 EDO05359.1 - 7.1e-18 63.6 25.1 2e-05 24.2 0.5 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 EDO05359.1 - 4.4e-06 26.2 31.3 0.02 14.5 0.9 4.4 5 0 0 5 5 5 4 Zinc knuckle AATF-Che1 PF13339.1 EDO05359.1 - 0.048 13.8 0.3 0.065 13.3 0.2 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor zf-CCHC_5 PF14787.1 EDO05359.1 - 0.2 11.1 27.4 0.33 10.4 0.1 4.0 5 0 0 5 5 5 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.1 EDO05359.1 - 1.2 8.7 18.9 0.17 11.3 0.6 3.9 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_3 PF13917.1 EDO05359.1 - 3.6 7.3 17.0 3.1 7.6 1.6 3.8 1 1 2 3 3 3 0 Zinc knuckle Amnionless PF14828.1 EDO05359.1 - 3.9 5.8 8.7 5.4 5.3 6.1 1.2 1 0 0 1 1 1 0 Amnionless zf-DHHC PF01529.15 EDO05360.1 - 3.1e-30 104.8 10.4 4.1e-30 104.4 7.2 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase COX2_TM PF02790.10 EDO05360.1 - 0.039 13.9 5.9 1.6 8.7 2.3 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Corona_7 PF02398.11 EDO05360.1 - 0.51 10.8 5.6 0.11 13.0 1.6 1.6 2 0 0 2 2 2 0 Coronavirus protein 7 DUF2244 PF10003.4 EDO05360.1 - 6.2 6.1 5.6 0.37 10.1 0.4 1.5 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Methyltransf_11 PF08241.7 EDO05361.1 - 2.2e-13 50.4 0.1 4.6e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO05361.1 - 1e-07 31.6 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO05361.1 - 3.8e-05 23.4 0.0 5.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO05361.1 - 4.9e-05 23.6 0.5 0.00015 22.0 0.1 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO05361.1 - 0.00044 20.2 0.0 0.00084 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO05361.1 - 0.001 19.6 0.0 0.0019 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO05361.1 - 0.0043 16.1 0.0 0.0073 15.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 EDO05361.1 - 0.0052 16.1 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.7 EDO05361.1 - 0.01 16.2 0.1 0.025 15.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EDO05361.1 - 0.083 11.9 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ebp2 PF05890.7 EDO05362.1 - 2e-29 102.7 27.4 2.4e-29 102.5 19.0 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Brix PF04427.13 EDO05363.1 - 9.3e-34 116.7 0.0 1.3e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain Josephin PF02099.12 EDO05364.1 - 1.3e-17 63.8 0.0 1.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Josephin UBX PF00789.15 EDO05364.1 - 1.1e-07 31.7 0.0 3.9e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 UBX domain EF-hand_7 PF13499.1 EDO05365.1 - 2.9e-06 27.3 0.4 0.0022 18.0 0.3 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EDO05365.1 - 1.3e-05 24.6 0.6 0.0052 16.5 0.1 3.3 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EDO05365.1 - 0.00025 20.1 0.2 0.0076 15.4 0.0 3.2 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 EDO05365.1 - 0.0007 19.1 1.0 0.45 10.1 0.0 4.1 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_5 PF13202.1 EDO05365.1 - 0.033 13.5 0.4 0.17 11.2 0.0 2.4 3 0 0 3 3 3 0 EF hand EFhand_Ca_insen PF08726.5 EDO05365.1 - 0.044 13.7 0.2 11 6.1 0.1 3.0 2 1 0 2 2 2 0 Ca2+ insensitive EF hand Rho_N PF07498.7 EDO05365.1 - 0.13 12.0 0.0 0.42 10.4 0.0 1.9 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain TK PF00265.13 EDO05366.1 - 0.041 13.4 2.0 0.22 11.0 0.1 2.4 2 0 0 2 2 2 0 Thymidine kinase Rapamycin_bind PF08771.6 EDO05366.1 - 0.042 13.9 0.9 0.16 12.0 0.1 2.5 2 1 1 3 3 3 0 Rapamycin binding domain Syntaxin_2 PF14523.1 EDO05366.1 - 0.71 9.9 3.1 0.76 9.8 0.9 2.0 2 0 0 2 2 2 0 Syntaxin-like protein DUF2935 PF11155.3 EDO05366.1 - 2.3 8.3 5.0 6.8 6.8 1.5 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF2935) Ribosomal_L3 PF00297.17 EDO05367.1 - 8.3e-104 346.6 2.9 1e-103 346.3 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 HTH_Tnp_1_2 PF13022.1 EDO05367.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase ENTH PF01417.15 EDO05369.1 - 5.7e-21 74.6 0.0 9.7e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 ENTH domain Marek_SORF3 PF07153.6 EDO05370.1 - 0.037 12.7 0.3 0.064 11.9 0.2 1.3 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein Tim54 PF11711.3 EDO05370.1 - 0.068 11.7 1.0 0.11 11.0 0.7 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EMG1 PF03587.9 EDO05371.1 - 1.8e-47 161.2 0.0 2.2e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase CNRIP1 PF15043.1 EDO05371.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 CB1 cannabinoid receptor-interacting protein 1 RNase_H2-Ydr279 PF09468.5 EDO05372.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) TFIIS_M PF07500.9 EDO05373.1 - 3.9e-27 94.5 1.9 3.9e-27 94.5 1.3 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EDO05373.1 - 2.6e-19 68.5 3.5 4.8e-19 67.6 2.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EDO05373.1 - 4.3e-13 48.5 0.8 9.5e-13 47.4 0.6 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Cytochrom_NNT PF03264.9 EDO05373.1 - 0.058 12.8 1.1 0.11 11.8 0.7 1.5 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Elf1 PF05129.8 EDO05373.1 - 0.083 12.5 0.9 0.19 11.4 0.6 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Cytochrome_C7 PF14522.1 EDO05373.1 - 0.091 12.4 0.2 0.22 11.1 0.2 1.6 1 0 0 1 1 1 0 Cytochrome c7 Cytochrome_C554 PF13435.1 EDO05373.1 - 1 9.4 5.1 0.19 11.7 0.8 1.8 2 0 0 2 2 2 0 Cytochrome c554 and c-prime Tho2 PF11262.3 EDO05374.1 - 0.016 14.2 0.2 0.058 12.4 0.0 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 WD40 PF00400.27 EDO05375.1 - 4.8e-13 48.4 12.5 0.058 13.3 0.4 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF3312 PF11768.3 EDO05375.1 - 0.092 10.9 0.0 0.62 8.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) HA2 PF04408.18 EDO05376.1 - 4.1e-30 103.8 0.1 1.3e-29 102.1 0.1 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDO05376.1 - 2.2e-29 101.5 0.5 6.8e-29 100.0 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EDO05376.1 - 3.9e-09 36.2 0.0 1.1e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EDO05376.1 - 2.1e-07 30.9 1.3 7.7e-07 29.1 0.6 2.2 2 0 0 2 2 2 1 S1 RNA binding domain DEAD PF00270.24 EDO05376.1 - 8.6e-06 25.3 0.1 2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDO05376.1 - 1.4e-05 25.2 0.0 5.9e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EDO05376.1 - 0.0023 16.8 0.0 0.0047 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 EDO05376.1 - 0.045 13.7 0.4 0.55 10.2 0.0 2.9 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA_29 PF13555.1 EDO05376.1 - 0.091 12.3 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Spt4 PF06093.8 EDO05377.1 - 2.4e-17 62.5 0.2 8e-17 60.8 0.1 1.7 1 1 0 1 1 1 1 Spt4/RpoE2 zinc finger GLE1 PF07817.8 EDO05378.1 - 9.5e-16 57.5 0.2 9.5e-16 57.5 0.1 1.7 2 0 0 2 2 2 1 GLE1-like protein zf-RING-like PF08746.6 EDO05378.1 - 0.025 14.5 0.2 0.069 13.1 0.1 1.7 1 0 0 1 1 1 0 RING-like domain DUF2057 PF09829.4 EDO05378.1 - 0.18 11.4 7.5 11 5.5 0.0 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2057) Fib_alpha PF08702.5 EDO05378.1 - 5.3 7.1 9.4 1 9.4 1.5 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PI3_PI4_kinase PF00454.22 EDO05379.1 - 1.9e-30 106.1 0.1 1.2e-28 100.1 0.1 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EDO05379.1 - 3.1e-10 39.5 0.0 5.9e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Thiolase_N PF00108.18 EDO05380.1 - 1.5e-31 109.3 0.0 2.5e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDO05380.1 - 1.4e-19 69.7 0.0 2.6e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EDO05380.1 - 0.031 13.9 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.7 EDO05380.1 - 0.033 13.2 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein MSA-2c PF12238.3 EDO05381.1 - 7.9e-91 303.2 2.9 7.9e-91 303.2 2.0 1.4 2 0 0 2 2 2 1 Merozoite surface antigen 2c Viral_DNA_Zn_bi PF03728.8 EDO05381.1 - 0.093 12.8 0.6 0.18 11.8 0.0 1.8 2 1 0 2 2 2 0 Viral DNA-binding protein, zinc binding domain Spc7_N PF15402.1 EDO05381.1 - 0.44 8.4 6.3 0.71 7.8 4.3 1.3 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Pex14_N PF04695.8 EDO05381.1 - 0.71 9.9 7.2 0.42 10.6 3.3 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MSA-2c PF12238.3 EDO05382.1 - 1.9e-87 292.2 28.1 1.9e-80 269.3 6.2 2.4 2 1 1 3 3 3 2 Merozoite surface antigen 2c MSA-2c PF12238.3 EDO05383.1 - 2e-83 279.0 31.2 2e-76 256.2 8.4 2.4 2 1 1 3 3 3 2 Merozoite surface antigen 2c Sp100 PF03172.8 EDO05383.1 - 0.022 14.7 1.1 0.15 12.0 0.1 2.2 1 1 1 2 2 2 0 Sp100 domain DUF605 PF04652.11 EDO05383.1 - 0.11 11.8 20.4 0.19 11.1 14.1 1.4 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EDO05383.1 - 5.8 5.0 19.2 1.8 6.6 11.1 1.7 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF2413 PF10310.4 EDO05383.1 - 9.5 4.9 8.8 18 3.9 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) MSA-2c PF12238.3 EDO05384.1 - 9.1e-52 175.7 1.7 1.3e-51 175.2 1.2 1.2 1 0 0 1 1 1 1 Merozoite surface antigen 2c DUF162 PF02589.10 EDO05384.1 - 0.039 13.4 0.0 0.055 12.9 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 ALMT PF11744.3 EDO05386.1 - 0.034 12.7 0.5 0.046 12.3 0.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Bax1-I PF01027.15 EDO05387.1 - 4.6e-24 85.1 31.8 5.3e-24 84.9 22.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 EmrE PF13536.1 EDO05387.1 - 1.1 9.4 21.5 0.12 12.6 11.4 2.0 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF2839 PF10999.3 EDO05387.1 - 9 6.4 7.8 1.7 8.7 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2839) MSA-2c PF12238.3 EDO05388.1 - 1.4e-20 73.8 21.9 3.4e-18 66.0 15.2 2.1 1 1 0 1 1 1 1 Merozoite surface antigen 2c rpo132 PF12415.3 EDO05388.1 - 0.1 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase SIR2 PF02146.12 EDO05389.1 - 2.1e-26 92.7 0.0 3.1e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family zf-Nse PF11789.3 EDO05390.1 - 4.8e-12 45.2 0.1 8.1e-12 44.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EDO05390.1 - 0.0033 17.2 0.6 0.017 14.9 0.1 2.2 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EDO05390.1 - 0.017 14.8 0.1 0.11 12.2 0.1 2.3 2 1 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.2 EDO05390.1 - 0.034 14.2 1.6 0.15 12.2 1.1 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 EDO05390.1 - 0.57 9.7 3.3 0.99 8.9 0.9 2.4 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger GTP_EFTU PF00009.22 EDO05391.1 - 1.4e-59 200.7 0.0 2e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EDO05391.1 - 1.3e-33 115.1 0.0 4.2e-33 113.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EDO05391.1 - 2.9e-21 75.1 0.0 6.2e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EDO05391.1 - 5.1e-15 55.0 0.0 1e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EDO05391.1 - 1.8e-12 47.1 1.3 3.2e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO05391.1 - 0.0005 20.0 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cwf21 PF08312.7 EDO05392.1 - 4.5e-06 26.4 5.5 1.1e-05 25.1 3.8 1.8 1 0 0 1 1 1 1 cwf21 domain NapE PF06796.6 EDO05393.1 - 0.15 11.3 0.1 0.37 10.1 0.1 1.6 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE Apolipoprotein PF01442.13 EDO05394.1 - 0.00015 21.3 25.0 0.042 13.3 4.9 4.1 1 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain Dynein_light PF01221.13 EDO05394.1 - 0.1 12.6 0.1 0.1 12.6 0.0 4.4 4 1 1 5 5 5 0 Dynein light chain type 1 Snapin_Pallidin PF14712.1 EDO05394.1 - 0.68 10.2 21.4 4.3 7.7 0.0 5.4 4 1 2 6 6 6 0 Snapin/Pallidin Uso1_p115_C PF04871.8 EDO05395.1 - 0.47 10.3 5.0 1.2 9.0 3.5 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HhH-GPD PF00730.20 EDO05396.1 - 3.3e-25 88.4 0.0 4.1e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EDO05396.1 - 2.8e-08 33.0 0.0 7.4e-08 31.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EDO05396.1 - 0.058 13.5 0.0 0.38 10.9 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain Cdd1 PF11731.3 EDO05396.1 - 0.074 12.9 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 Pathogenicity locus DUF2413 PF10310.4 EDO05397.1 - 0.01 14.7 3.9 0.012 14.5 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Ribosomal_L19e PF01280.15 EDO05398.1 - 1.4e-58 196.8 7.1 1.4e-58 196.8 4.9 1.4 2 0 0 2 2 2 1 Ribosomal protein L19e DUF2407 PF10302.4 EDO05398.1 - 0.23 11.6 1.4 0.7 10.1 1.0 1.8 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Fe_hyd_lg_C PF02906.9 EDO05399.1 - 3.6e-56 190.5 0.0 7.2e-56 189.5 0.0 1.5 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain ABC_tran PF00005.22 EDO05400.1 - 1.5e-29 103.0 0.0 7.4e-15 55.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDO05400.1 - 1.7e-10 40.7 7.5 1.7e-10 40.7 5.2 3.9 4 0 0 4 4 3 1 ABC transporter transmembrane region AAA_29 PF13555.1 EDO05400.1 - 6.1e-09 35.2 0.5 0.0041 16.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EDO05400.1 - 1.5e-07 30.6 0.3 0.001 18.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EDO05400.1 - 3.3e-07 29.9 0.3 0.005 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EDO05400.1 - 7e-07 29.2 0.6 0.015 15.2 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 EDO05400.1 - 7.7e-07 29.6 1.9 0.018 15.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EDO05400.1 - 2.8e-06 26.9 0.0 0.023 14.1 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_16 PF13191.1 EDO05400.1 - 1e-05 25.6 0.6 0.024 14.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EDO05400.1 - 1.9e-05 24.2 0.0 0.041 13.3 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 EDO05400.1 - 2e-05 25.3 0.0 0.057 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EDO05400.1 - 3.4e-05 23.9 0.5 0.16 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EDO05400.1 - 4.6e-05 22.6 0.2 0.048 12.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin SMC_N PF02463.14 EDO05400.1 - 7.8e-05 22.0 0.4 0.63 9.2 0.0 3.4 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 EDO05400.1 - 9.8e-05 22.0 0.5 1.5 8.3 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EDO05400.1 - 0.00011 21.8 2.3 0.0051 16.5 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain T2SE PF00437.15 EDO05400.1 - 0.00013 20.9 0.5 0.14 11.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein NACHT PF05729.7 EDO05400.1 - 0.00015 21.4 1.5 0.29 10.7 0.1 2.7 2 0 0 2 2 2 2 NACHT domain Miro PF08477.8 EDO05400.1 - 0.00017 22.0 0.5 0.22 12.0 0.2 2.8 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 EDO05400.1 - 0.00027 21.1 0.5 0.014 15.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EDO05400.1 - 0.00048 19.9 1.7 0.81 9.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin family AAA_22 PF13401.1 EDO05400.1 - 0.00053 20.1 0.0 0.87 9.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDO05400.1 - 0.00066 19.9 1.9 1.3 9.3 1.0 3.1 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EDO05400.1 - 0.00092 18.9 0.1 0.045 13.4 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 EDO05400.1 - 0.0014 18.4 1.7 0.25 11.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EDO05400.1 - 0.0022 17.4 6.1 0.023 14.1 0.4 2.8 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 EDO05400.1 - 0.0052 16.6 5.1 0.0081 16.0 0.4 2.8 3 0 0 3 3 3 1 Domain of unknown function DUF87 MobB PF03205.9 EDO05400.1 - 0.013 15.1 0.3 0.93 9.1 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EDO05400.1 - 0.019 13.7 0.3 1.5 7.5 0.1 2.3 2 0 0 2 2 2 0 ArgK protein SbcCD_C PF13558.1 EDO05400.1 - 0.02 14.8 0.0 0.059 13.2 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EDO05400.1 - 0.027 14.6 0.1 7.6 6.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.1 EDO05400.1 - 0.03 13.9 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EDO05400.1 - 0.047 12.5 0.4 3.1 6.5 0.2 2.3 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.12 EDO05400.1 - 0.059 12.8 0.2 15 5.0 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 EDO05400.1 - 0.062 13.0 1.1 7.7 6.1 0.1 2.3 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 EDO05400.1 - 0.079 12.6 2.9 2.6 7.7 0.2 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.13 EDO05400.1 - 0.079 12.2 0.3 3.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Mg_chelatase PF01078.16 EDO05400.1 - 0.097 11.8 0.3 3.1 6.8 0.1 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EDO05400.1 - 0.11 12.0 0.3 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EDO05400.1 - 0.11 11.9 0.1 13 5.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EDO05400.1 - 0.11 12.3 2.4 5.1 7.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EDO05400.1 - 0.14 11.7 0.7 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 EDO05400.1 - 0.15 11.9 0.0 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EDO05400.1 - 0.33 9.9 0.0 7.6 5.4 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain TrwB_AAD_bind PF10412.4 EDO05400.1 - 0.63 8.5 1.3 5.6 5.4 0.1 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.12 EDO05400.1 - 1 8.7 2.7 12 5.2 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein Ank_5 PF13857.1 EDO05402.1 - 0.12 12.6 0.0 1.4 9.2 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Big_2 PF02368.13 EDO05403.1 - 6.6 6.6 11.6 12 5.8 0.1 5.7 8 0 0 8 8 8 0 Bacterial Ig-like domain (group 2) Beta-Casp PF10996.3 EDO05406.1 - 4e-21 75.2 0.0 1.2e-20 73.7 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EDO05406.1 - 2.8e-13 49.4 0.0 6.7e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EDO05406.1 - 3.2e-13 49.6 0.0 2e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EDO05406.1 - 8e-12 45.2 0.9 5.1e-08 32.7 0.7 3.2 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily FtsJ PF01728.14 EDO05407.1 - 4.6e-31 108.1 0.1 1.7e-22 80.2 0.0 2.7 2 1 0 3 3 3 2 FtsJ-like methyltransferase CARD PF00619.16 EDO05407.1 - 0.018 14.8 0.1 7.4 6.4 0.0 3.5 3 0 0 3 3 3 0 Caspase recruitment domain HTH_10 PF04967.7 EDO05408.1 - 0.012 15.1 0.1 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_23 PF13384.1 EDO05408.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain CAP_C PF08603.6 EDO05410.1 - 1.3e-40 138.3 7.1 1.5e-40 138.1 5.0 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EDO05410.1 - 0.31 10.4 10.1 1 8.7 6.6 1.9 1 1 1 2 2 2 0 Tubulin binding cofactor C SAP PF02037.22 EDO05411.1 - 3.8e-07 29.4 4.1 7.9e-07 28.4 2.8 1.6 1 0 0 1 1 1 1 SAP domain PhoD PF09423.5 EDO05412.1 - 1e-17 63.8 0.0 5.7e-09 35.0 0.0 3.3 3 0 0 3 3 3 3 PhoD-like phosphatase Ank_2 PF12796.2 EDO05413.1 - 9.5e-47 157.2 5.0 4.6e-17 62.1 0.1 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDO05413.1 - 4.8e-38 128.8 6.0 1.5e-12 47.6 0.1 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EDO05413.1 - 3e-31 105.6 0.6 8e-08 31.7 0.0 5.8 5 1 0 5 5 5 4 Ankyrin repeat RNA_GG_bind PF10258.4 EDO05413.1 - 7.9e-31 105.6 0.0 1.9e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 PHAX RNA-binding domain Ank_5 PF13857.1 EDO05413.1 - 6.5e-23 80.2 1.0 8.1e-10 38.6 0.1 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO05413.1 - 1.3e-21 74.4 0.9 0.0018 18.3 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat ParA PF10609.4 EDO05413.1 - 0.093 12.6 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 ParA/MinD ATPase like DUF936 PF06075.7 EDO05413.1 - 7.5 5.3 18.4 1.2 7.9 10.0 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF936) Methyltransf_16 PF10294.4 EDO05414.1 - 2.3e-07 30.4 0.0 0.00014 21.4 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase MTS PF05175.9 EDO05414.1 - 0.0021 17.4 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF2905 PF11146.3 EDO05415.1 - 0.1 12.5 3.5 1 9.3 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2905) Cpn60_TCP1 PF00118.19 EDO05416.1 - 4.1e-142 474.2 5.2 4.6e-142 474.0 3.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2161 PF09929.4 EDO05416.1 - 0.052 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) CDC50 PF03381.10 EDO05417.1 - 2.6e-26 92.4 2.8 5.9e-26 91.2 1.9 1.6 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RNA_pol_Rpb1_5 PF04998.12 EDO05418.1 - 7.4e-99 330.4 0.1 1.6e-98 329.3 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EDO05418.1 - 1.1e-94 317.4 1.1 1.5e-94 317.0 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EDO05418.1 - 3.4e-66 222.2 0.0 7.8e-66 221.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EDO05418.1 - 1.9e-46 157.6 0.0 5e-46 156.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_6 PF04992.9 EDO05418.1 - 4.6e-45 153.6 0.2 1e-44 152.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.7 EDO05418.1 - 3e-42 143.5 4.1 6.5e-42 142.4 2.8 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EDO05418.1 - 2e-37 127.2 0.0 4.9e-37 125.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EDO05418.1 - 3.7e-11 42.1 224.4 0.015 15.3 5.0 14.5 12 3 0 13 13 13 10 RNA polymerase Rpb1 C-terminal repeat Band_7 PF01145.20 EDO05419.1 - 2.2e-26 92.8 0.2 2.2e-26 92.8 0.1 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EDO05419.1 - 0.003 17.1 0.8 0.025 14.0 0.0 2.2 2 0 0 2 2 2 1 SPFH domain-Band 7 family NAD_kinase PF01513.16 EDO05419.1 - 0.005 15.6 0.5 0.1 11.3 0.0 2.3 2 0 0 2 2 2 1 ATP-NAD kinase L_biotic_typeA PF04604.8 EDO05421.1 - 0.062 12.9 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Type-A lantibiotic Ribosomal_L21p PF00829.16 EDO05423.1 - 4e-21 74.9 0.1 6.6e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein GTP_EFTU PF00009.22 EDO05424.1 - 1.2e-31 109.5 1.7 1.3e-30 106.2 1.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO05424.1 - 4.2e-06 26.7 0.0 1.1e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EDO05424.1 - 1.7e-05 24.3 0.0 3.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Ras family PduV-EutP PF10662.4 EDO05424.1 - 0.00025 20.5 0.1 0.00063 19.2 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EDO05424.1 - 0.00047 20.6 0.0 0.0016 18.9 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO05424.1 - 0.00099 18.3 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family IF-2 PF11987.3 EDO05424.1 - 0.008 16.0 0.0 0.092 12.6 0.0 2.4 1 1 1 2 2 2 1 Translation-initiation factor 2 FeoB_N PF02421.13 EDO05424.1 - 0.0087 15.3 0.3 0.082 12.1 0.2 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B DEAD PF00270.24 EDO05425.1 - 1e-40 139.0 0.1 5e-40 136.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO05425.1 - 2.4e-20 72.1 0.0 1.4e-19 69.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EDO05425.1 - 2.3e-08 33.7 2.8 2.3e-08 33.7 1.9 2.8 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ResIII PF04851.10 EDO05425.1 - 0.00012 21.9 2.0 0.00042 20.1 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDO05425.1 - 0.057 13.5 0.3 0.62 10.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain HSP70 PF00012.15 EDO05426.1 - 4e-31 107.6 0.8 1.3e-28 99.3 0.0 2.5 2 1 0 2 2 2 2 Hsp70 protein TPR_11 PF13414.1 EDO05426.1 - 1.8e-14 53.1 9.5 5e-08 32.4 0.2 3.6 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EDO05426.1 - 6.6e-07 28.6 11.7 0.015 14.9 0.1 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDO05426.1 - 6.5e-06 25.9 0.1 0.00054 19.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDO05426.1 - 0.00014 22.1 0.8 0.0037 17.5 0.0 3.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDO05426.1 - 0.0002 21.0 9.9 0.21 11.6 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 EDO05426.1 - 0.00087 19.0 0.1 0.0031 17.3 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDO05426.1 - 0.0014 19.0 0.3 1.2 10.0 0.3 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDO05426.1 - 0.17 12.6 0.0 0.17 12.6 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO05426.1 - 4.7 7.2 8.2 0.27 11.1 0.2 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Flavokinase PF01687.12 EDO05427.1 - 3.3e-25 88.3 0.0 5.9e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase MMR_HSR1 PF01926.18 EDO05428.1 - 6.4e-18 64.7 0.0 1.3e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EDO05428.1 - 8.5e-14 51.1 0.0 1.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EDO05428.1 - 2.8e-12 46.1 0.0 4.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EDO05428.1 - 0.0001 22.1 0.0 0.043 13.6 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AAA_28 PF13521.1 EDO05428.1 - 0.0024 17.8 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO05428.1 - 0.0076 17.0 1.2 0.054 14.3 0.9 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO05428.1 - 0.014 15.7 0.1 0.029 14.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.11 EDO05428.1 - 0.026 13.6 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Mg_chelatase PF01078.16 EDO05428.1 - 0.027 13.6 0.0 0.063 12.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EDO05428.1 - 0.032 14.4 0.1 3.9 7.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 EDO05428.1 - 0.04 12.7 0.5 0.37 9.5 0.0 2.3 2 1 1 3 3 3 0 ArgK protein Miro PF08477.8 EDO05428.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Ribosomal_S13_N PF08069.7 EDO05429.1 - 1.6e-27 95.0 0.8 2.9e-27 94.2 0.6 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EDO05429.1 - 1.4e-20 72.8 0.4 2.6e-20 71.9 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 PAX PF00292.13 EDO05429.1 - 0.097 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain HMG_box_2 PF09011.5 EDO05430.1 - 5.5e-05 23.4 0.0 8.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 HMG-box domain CBFD_NFYB_HMF PF00808.18 EDO05430.1 - 0.00097 19.1 0.0 0.0021 18.0 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Myosin_head PF00063.16 EDO05431.1 - 7e-174 579.6 0.9 1e-173 579.0 0.6 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 EDO05431.1 - 0.0075 16.4 0.1 0.073 13.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EDO05431.1 - 0.062 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MurB_C PF02873.11 EDO05433.1 - 0.0063 16.2 0.0 0.011 15.4 0.0 1.6 1 1 0 1 1 1 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Exo_endo_phos PF03372.18 EDO05434.1 - 1.4e-18 67.7 0.3 3e-18 66.6 0.2 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.17 EDO05435.1 - 1.1e-55 185.1 0.0 1.9e-19 69.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO05435.1 - 2.2e-39 133.2 0.1 1.4e-12 47.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO05435.1 - 5.3e-32 109.4 0.4 6.5e-11 41.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 EDO05435.1 - 2.5e-09 36.8 3.2 7.2e-09 35.3 2.2 1.8 1 0 0 1 1 1 1 WW domain RNA_bind PF08675.6 EDO05435.1 - 5.1e-06 26.3 0.0 0.061 13.3 0.0 3.0 3 0 0 3 3 3 2 RNA binding domain Limkain-b1 PF11608.3 EDO05435.1 - 0.00011 21.8 0.1 0.64 9.8 0.0 2.6 2 0 0 2 2 2 2 Limkain b1 Nup35_RRM PF05172.8 EDO05435.1 - 0.0022 17.7 0.0 0.059 13.1 0.0 2.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RNB PF00773.14 EDO05436.1 - 1.5e-95 320.2 0.0 2.4e-95 319.5 0.0 1.4 1 0 0 1 1 1 1 RNB domain PEPCK_ATP PF01293.15 EDO05437.1 - 2.2e-211 702.3 0.0 2.6e-211 702.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 EDO05437.1 - 0.06 12.8 1.2 0.11 12.0 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EDO05437.1 - 0.092 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDO05437.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AP2 PF00847.15 EDO05438.1 - 2.7e-06 27.4 0.1 0.28 11.3 0.0 3.4 3 0 0 3 3 3 3 AP2 domain DUF192 PF02643.10 EDO05439.1 - 0.0026 17.4 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 UDPGP PF01704.13 EDO05440.1 - 3.5e-21 75.1 0.0 4.6e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EDO05440.1 - 0.0009 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Kelch_1 PF01344.20 EDO05441.1 - 1e-55 185.0 3.2 1.5e-11 43.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EDO05441.1 - 3.7e-33 112.3 0.5 5.2e-06 26.3 0.0 6.3 4 1 2 6 6 6 6 Kelch motif Kelch_4 PF13418.1 EDO05441.1 - 1.2e-25 89.0 1.3 0.00018 21.2 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EDO05441.1 - 4.7e-22 77.5 5.3 0.0013 18.8 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB_2 PF02214.17 EDO05441.1 - 1.6e-18 66.6 0.0 5.2e-18 65.0 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.1 EDO05441.1 - 2.4e-10 40.1 0.6 1.3 9.0 0.0 6.8 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.10 EDO05441.1 - 1.4e-08 34.1 4.2 0.66 9.8 0.0 6.6 7 0 0 7 7 7 3 Kelch motif DUF501 PF04417.7 EDO05441.1 - 0.0027 17.5 1.2 0.0027 17.5 0.8 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF501) Chorein_N PF12624.2 EDO05442.1 - 7.9e-19 67.3 0.8 1.6e-18 66.3 0.2 1.8 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter WD40 PF00400.27 EDO05443.1 - 1.5e-38 129.3 3.3 8.1e-07 28.6 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EDO05443.1 - 9.1e-14 50.4 2.5 9.1e-14 50.4 1.7 1.9 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Nup160 PF11715.3 EDO05443.1 - 0.008 14.3 0.1 0.98 7.4 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EDO05443.1 - 0.029 13.8 0.0 0.058 12.8 0.0 1.5 1 1 0 1 1 1 0 PQQ-like domain MFS_1 PF07690.11 EDO05444.1 - 5e-11 41.9 7.0 5e-11 41.9 4.9 4.0 2 2 0 3 3 3 2 Major Facilitator Superfamily YbhQ PF11076.3 EDO05444.1 - 0.39 10.3 9.5 0.2 11.2 2.4 3.6 3 0 0 3 3 3 0 Putative inner membrane protein YbhQ GCV_T PF01571.16 EDO05445.1 - 1.2e-28 99.8 0.0 1.9e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EDO05445.1 - 1.6e-24 85.7 0.0 5.1e-24 84.1 0.0 2.0 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain HSP70 PF00012.15 EDO05446.1 - 1.6e-49 168.3 14.8 1.6e-49 168.3 10.2 2.8 2 1 0 2 2 2 1 Hsp70 protein Hydantoinase_A PF01968.13 EDO05446.1 - 0.42 9.6 4.4 0.13 11.2 0.1 2.2 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase FHA PF00498.21 EDO05447.1 - 1.2e-12 47.7 1.8 1.1e-11 44.6 0.2 2.8 3 0 0 3 3 3 1 FHA domain RINGv PF12906.2 EDO05447.1 - 4.5e-10 39.4 7.7 4.5e-10 39.4 5.4 1.8 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EDO05447.1 - 0.05 13.4 6.3 0.099 12.4 4.3 1.6 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 EDO05447.1 - 0.12 12.3 5.6 0.12 12.3 2.7 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain OTCace_N PF02729.16 EDO05448.1 - 9.9e-46 154.9 0.0 1.6e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EDO05448.1 - 2.2e-38 131.6 0.1 1.2e-37 129.1 0.0 2.2 3 0 0 3 3 3 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain NAD_Gly3P_dh_N PF01210.18 EDO05448.1 - 0.0036 17.0 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HVSL PF09749.4 EDO05450.1 - 3.7e-26 91.6 0.2 7.2e-26 90.6 0.1 1.4 1 1 0 2 2 2 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 EDO05450.1 - 8.7e-06 25.5 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Thioredoxin PF00085.15 EDO05451.1 - 1.2e-18 66.6 0.0 1.8e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EDO05451.1 - 4.6e-06 26.8 0.0 1.6e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDO05451.1 - 6.4e-05 23.0 0.0 0.0028 17.7 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EDO05451.1 - 0.00028 20.8 0.0 0.00047 20.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.11 EDO05451.1 - 0.008 14.9 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Phosducin AhpC-TSA PF00578.16 EDO05451.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family HyaE PF07449.6 EDO05451.1 - 0.042 13.7 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE KaiB PF07689.7 EDO05451.1 - 0.05 13.0 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 KaiB domain Rhomboid PF01694.17 EDO05452.1 - 1.4e-12 47.8 19.4 2.1e-10 40.7 4.6 2.4 2 0 0 2 2 2 2 Rhomboid family IMCp PF12314.3 EDO05455.1 - 5.7e-21 74.4 62.1 2.5e-13 49.9 20.9 3.0 2 1 1 3 3 3 2 Inner membrane complex protein Dopey_N PF04118.9 EDO05456.1 - 1.2e-103 346.1 2.6 1.2e-103 346.1 1.8 2.1 2 0 0 2 2 2 1 Dopey, N-terminal Bromodomain PF00439.20 EDO05457.1 - 3.4e-26 90.9 2.8 7e-26 89.9 1.0 2.1 2 0 0 2 2 2 1 Bromodomain Acetyltransf_7 PF13508.1 EDO05457.1 - 2e-11 43.8 1.6 3.9e-11 42.9 1.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDO05457.1 - 1.8e-10 40.6 0.1 3.4e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDO05457.1 - 6.8e-05 22.9 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDO05457.1 - 0.0015 18.6 0.1 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDO05457.1 - 0.007 16.2 0.2 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDO05457.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein CIAPIN1 PF05093.8 EDO05458.1 - 4.9e-20 71.4 12.5 2.2e-18 66.1 8.7 2.3 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis tRNA-synt_2b PF00587.20 EDO05459.1 - 2.4e-59 199.7 0.0 8.2e-59 198.0 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDO05459.1 - 4.1e-22 77.9 0.0 9e-21 73.6 0.0 2.7 3 0 0 3 3 3 1 Anticodon binding domain zf-DNL PF05180.7 EDO05460.1 - 8.3e-28 95.9 0.2 1.1e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 DNL zinc finger MutS_V PF00488.16 EDO05463.1 - 2.9e-87 291.9 0.1 4.5e-87 291.3 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDO05463.1 - 3.3e-32 111.9 0.1 7.4e-32 110.7 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EDO05463.1 - 7.1e-08 32.5 1.2 1.9e-07 31.1 0.8 1.8 1 0 0 1 1 1 1 MutS family domain IV FlaC_arch PF05377.6 EDO05463.1 - 0.12 12.2 6.7 0.94 9.4 0.1 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) LigT_PEase PF02834.11 EDO05464.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 LigT like Phosphoesterase VESA1_N PF12785.2 EDO05465.1 - 2.5e-198 659.7 18.8 5.4e-198 658.6 13.1 1.5 1 0 0 1 1 1 1 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05466.1 - 8.7e-211 700.8 20.4 8.7e-211 700.8 14.2 2.5 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 DUF3236 PF11576.3 EDO05466.1 - 0.27 10.6 1.0 0.51 9.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Muted PF14942.1 EDO05466.1 - 1.1 9.1 6.5 0.15 11.8 0.9 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein FliE PF02049.13 EDO05466.1 - 1.1 9.3 8.8 0.099 12.6 2.4 2.0 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE DUF948 PF06103.6 EDO05466.1 - 2.4 8.0 7.9 2.4 8.0 1.6 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) G0-G1_switch_2 PF15103.1 EDO05468.1 - 0.11 12.6 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF2149 PF09919.4 EDO05468.1 - 0.12 12.4 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) VESA1_N PF12785.2 EDO05469.1 - 9e-146 486.4 6.5 1.4e-145 485.8 4.5 1.2 1 0 0 1 1 1 1 Variant erythrocyte surface antigen-1 F-box-like_2 PF13013.1 EDO05470.1 - 0.12 12.1 0.0 0.45 10.2 0.0 1.8 1 1 1 2 2 2 0 F-box-like domain DUF3420 PF11900.3 EDO05470.1 - 1.2 9.3 3.6 24 5.1 0.0 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF3420) F-box-like_2 PF13013.1 EDO05471.1 - 2.3e-08 33.7 0.4 4.7e-05 23.0 0.0 2.7 1 1 0 2 2 2 2 F-box-like domain DUF4630 PF15443.1 EDO05471.1 - 0.056 13.2 1.8 5.5 6.7 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4630) Telomerase_RBD PF12009.3 EDO05471.1 - 0.32 10.9 2.2 1.8 8.4 0.1 2.3 2 0 0 2 2 2 0 Telomerase ribonucleoprotein complex - RNA binding domain VESA1_N PF12785.2 EDO05472.1 - 5.3e-181 602.6 33.8 5.3e-181 602.6 23.4 3.3 3 1 0 3 3 3 1 Variant erythrocyte surface antigen-1 RPW8 PF05659.6 EDO05472.1 - 0.32 10.5 4.2 0.42 10.1 0.2 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PEP-utilisers_N PF05524.8 EDO05472.1 - 1 9.1 3.2 24 4.7 0.1 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4164 PF13747.1 EDO05472.1 - 2.3 8.4 4.9 1 9.5 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Spc7 PF08317.6 EDO05472.1 - 8.4 4.9 10.1 0.17 10.4 1.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein VESA1_N PF12785.2 EDO05473.1 - 3.3e-219 728.5 20.7 3.3e-219 728.5 14.3 2.2 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 FliJ PF02050.11 EDO05473.1 - 0.023 14.7 0.2 0.023 14.7 0.1 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein Baculo_PEP_C PF04513.7 EDO05473.1 - 0.042 13.6 0.7 12 5.7 0.1 3.7 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Latarcin PF10279.4 EDO05473.1 - 0.047 13.8 1.6 0.14 12.3 0.0 2.4 2 0 0 2 2 2 0 Latarcin precursor DUF2077 PF09850.4 EDO05473.1 - 0.11 11.9 0.2 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) Serine_rich PF08824.5 EDO05473.1 - 0.14 11.8 0.6 0.62 9.7 0.1 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain RPW8 PF05659.6 EDO05473.1 - 0.23 10.9 4.1 0.19 11.2 0.5 2.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BMFP PF04380.8 EDO05473.1 - 1.4 9.1 6.3 2 8.6 0.1 2.9 3 0 0 3 3 3 0 Membrane fusogenic activity DUF4618 PF15397.1 EDO05473.1 - 1.8 7.8 11.9 17 4.5 8.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF4175 PF13779.1 EDO05473.1 - 2.3 5.8 7.2 4.2 4.9 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1515 PF07439.6 EDO05473.1 - 2.7 7.8 4.3 5.5 6.8 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Adeno_IVa2 PF02456.10 EDO05474.1 - 0.027 13.1 0.1 0.03 12.9 0.1 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein BPL_LplA_LipB PF03099.14 EDO05475.1 - 2.5e-21 76.0 0.1 4.6e-20 71.8 0.0 2.7 3 0 0 3 3 3 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.4 EDO05475.1 - 7.4e-07 28.7 0.1 2.1e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus RCC1_2 PF13540.1 EDO05476.1 - 0.00011 21.7 0.4 0.01 15.4 0.0 2.4 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EDO05476.1 - 0.0055 16.8 0.2 4.6 7.5 0.0 2.5 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat CWC25 PF12542.3 EDO05477.1 - 6e-16 58.6 0.4 4.8e-15 55.7 0.0 2.8 2 0 0 2 2 2 1 Pre-mRNA splicing factor TMCO5 PF14992.1 EDO05477.1 - 0.26 10.3 5.7 0.051 12.7 1.3 1.7 2 0 0 2 2 2 0 TMCO5 family GTP_EFTU PF00009.22 EDO05478.1 - 1e-20 73.9 0.4 1.3e-19 70.3 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EDO05478.1 - 1.5e-11 44.1 0.0 3.4e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 Miro PF08477.8 EDO05478.1 - 1.1e-07 32.3 0.0 2.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDO05478.1 - 1.7e-07 31.1 0.0 3.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EDO05478.1 - 2.2e-05 23.8 0.0 4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Ras family PduV-EutP PF10662.4 EDO05478.1 - 0.00034 20.1 0.0 0.0029 17.0 0.0 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EDO05478.1 - 0.0021 17.8 0.1 0.0058 16.4 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MobB PF03205.9 EDO05478.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 EDO05478.1 - 0.012 14.8 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EDO05478.1 - 0.023 13.9 0.0 0.11 11.7 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Toxin-deaminase PF14424.1 EDO05478.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases zf-B_box PF00643.19 EDO05479.1 - 5.9e-10 38.8 20.0 5.5e-05 22.9 5.0 2.5 2 0 0 2 2 2 2 B-box zinc finger PH PF00169.24 EDO05479.1 - 3.2e-06 27.2 0.0 6.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 PH domain IBR PF01485.16 EDO05479.1 - 0.99 9.3 18.3 1.1 9.1 2.5 3.1 3 0 0 3 3 3 0 IBR domain HEAT PF02985.17 EDO05480.1 - 0.022 14.8 0.2 12 6.2 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat Phe_hydrox_dim PF07976.7 EDO05481.1 - 0.047 13.3 0.0 0.089 12.3 0.0 1.5 1 1 1 2 2 2 0 Phenol hydroxylase, C-terminal dimerisation domain Actin PF00022.14 EDO05482.1 - 4e-76 255.9 0.0 2.2e-75 253.5 0.0 2.1 1 1 0 1 1 1 1 Actin NGP1NT PF08153.7 EDO05483.1 - 2.8e-39 134.0 1.8 5.4e-39 133.1 1.3 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EDO05483.1 - 7.9e-17 61.2 0.0 2.8e-14 53.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase PP-binding PF00550.20 EDO05483.1 - 9.2e-08 32.2 0.1 2.1e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site FeoB_N PF02421.13 EDO05483.1 - 1.9e-07 30.4 0.0 0.00015 21.1 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B PP-binding_2 PF14573.1 EDO05483.1 - 1e-05 25.4 0.4 3e-05 23.9 0.3 1.8 1 0 0 1 1 1 1 Acyl-carrier Arf PF00025.16 EDO05483.1 - 0.00061 19.0 0.1 0.5 9.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 EDO05483.1 - 0.00082 18.5 0.0 0.0018 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDO05483.1 - 0.0012 18.7 1.3 1.3 8.7 0.0 3.7 3 1 1 4 4 4 1 Dynamin family GTP_EFTU PF00009.22 EDO05483.1 - 0.0022 17.4 0.2 0.52 9.7 0.1 2.8 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Hpt PF01627.18 EDO05483.1 - 0.16 11.9 0.1 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 Hpt domain SHS2_Rpb7-N PF03876.12 EDO05484.1 - 5.6e-10 39.2 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RRF PF01765.14 EDO05485.1 - 9.3e-35 119.5 0.6 1.3e-34 119.0 0.4 1.2 1 0 0 1 1 1 1 Ribosome recycling factor DUF883 PF05957.8 EDO05485.1 - 0.1 12.9 2.1 0.52 10.7 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) COG2 PF06148.6 EDO05485.1 - 0.34 10.7 3.9 0.48 10.2 1.1 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Macro PF01661.16 EDO05486.1 - 0.00041 20.2 0.0 0.0008 19.2 0.0 1.4 1 0 0 1 1 1 1 Macro domain CRAL_TRIO_2 PF13716.1 EDO05486.1 - 0.0032 17.3 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF866 PF05907.8 EDO05487.1 - 1.8e-21 76.2 0.0 2e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF2874 PF11396.3 EDO05487.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) Molydop_binding PF01568.16 EDO05487.1 - 0.13 12.0 0.1 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain IP_trans PF02121.13 EDO05488.1 - 2.5e-39 135.0 0.1 3.7e-39 134.4 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein PH PF00169.24 EDO05488.1 - 1.7e-08 34.6 1.5 1.8e-08 34.5 0.1 1.8 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EDO05488.1 - 0.0015 18.7 0.0 0.0046 17.1 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EDO05488.1 - 0.0021 18.3 2.0 0.022 14.9 0.9 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain EF-hand_1 PF00036.27 EDO05489.1 - 3.6e-37 122.8 8.5 1.6e-09 36.3 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EDO05489.1 - 1.1e-34 118.3 3.0 1.1e-19 70.3 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EDO05489.1 - 1.6e-30 104.4 8.5 1.9e-16 59.3 0.2 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EDO05489.1 - 1.1e-27 93.3 5.9 5.8e-09 35.0 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EDO05489.1 - 2.7e-26 89.6 6.6 3.6e-07 29.2 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EDO05489.1 - 7.2e-11 41.8 0.0 3.9e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EDO05489.1 - 3e-09 36.5 0.2 0.00019 21.1 0.0 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EDO05489.1 - 6.5e-07 29.3 0.0 0.00054 19.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EDO05489.1 - 5.1e-06 26.0 0.0 0.017 14.7 0.0 2.8 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.8 EDO05489.1 - 0.00014 21.4 0.1 0.062 12.8 0.0 2.6 2 1 1 3 3 3 1 Caleosin related protein EFhand_Ca_insen PF08726.5 EDO05489.1 - 0.00015 21.6 0.8 0.001 19.0 0.1 2.4 2 2 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 EDO05489.1 - 0.013 14.8 0.5 0.015 14.6 0.3 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) LNS2 PF08235.8 EDO05489.1 - 0.015 14.8 0.0 0.15 11.5 0.0 2.0 1 1 1 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) TerB PF05099.8 EDO05489.1 - 0.03 14.0 0.1 4 7.1 0.0 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB VCBS PF13517.1 EDO05489.1 - 0.067 13.5 0.7 8.9 6.7 0.2 2.4 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF853 PF05872.7 EDO05489.1 - 0.079 11.2 0.1 0.75 8.0 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) RNA_pol_Rpb4 PF03874.11 EDO05489.1 - 0.085 12.8 0.4 2.6 8.0 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb4 Toprim_2 PF13155.1 EDO05489.1 - 0.12 12.6 0.1 20 5.5 0.0 2.3 1 1 1 2 2 2 0 Toprim-like Fe_hyd_lg_C PF02906.9 EDO05489.1 - 0.13 11.5 0.7 0.51 9.5 0.4 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF3650 PF12368.3 EDO05489.1 - 4.4 6.8 6.7 20 4.7 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) DUF3661 PF12400.3 EDO05491.1 - 4.9e-27 94.5 4.2 2.2e-22 79.5 1.1 2.5 2 0 0 2 2 2 2 Vaculolar membrane protein Ribosomal_L22 PF00237.14 EDO05492.1 - 3.1e-31 107.4 0.0 4.6e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Baculo_LEF5 PF04838.7 EDO05494.1 - 0.043 13.5 0.1 0.051 13.3 0.1 1.2 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 Nucleoplasmin PF03066.10 EDO05495.1 - 0.19 11.2 4.7 0.29 10.6 3.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EDO05495.1 - 0.23 9.4 5.9 0.24 9.3 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 EDO05495.1 - 1.4 6.7 6.1 1.5 6.5 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen IMCp PF12314.3 EDO05496.1 - 1.5e-23 82.7 40.8 1.5e-23 82.7 28.3 5.0 1 1 2 4 4 4 2 Inner membrane complex protein DUF3674 PF12426.3 EDO05496.1 - 1.1 8.7 3.1 6.5 6.2 0.2 2.8 2 0 0 2 2 2 0 RNA dependent RNA polymerase FGGY_N PF00370.16 EDO05498.1 - 8e-62 208.7 0.5 1.1e-61 208.2 0.3 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EDO05498.1 - 9.5e-46 155.9 0.0 1.4e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 EDO05498.1 - 0.015 14.5 0.0 4.2 6.5 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Pox_A14 PF05767.7 EDO05499.1 - 0.031 14.2 0.1 0.031 14.2 0.1 2.1 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 Pkinase PF00069.20 EDO05500.1 - 7e-60 202.3 0.0 1.1e-59 201.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO05500.1 - 1.1e-33 116.4 0.0 1.6e-31 109.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDO05500.1 - 4.6e-09 35.6 0.0 7.7e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO05500.1 - 0.0014 18.4 0.1 0.023 14.4 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family DEAD PF00270.24 EDO05501.1 - 2.6e-49 166.9 0.1 6.2e-48 162.4 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO05501.1 - 7.8e-23 80.1 0.0 2.5e-22 78.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO05501.1 - 0.00012 21.9 0.0 0.0003 20.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDO05501.1 - 0.0013 17.6 0.0 0.0018 17.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4242 PF14026.1 EDO05501.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) FAINT PF04385.10 EDO05502.1 - 2.1e-22 78.7 9.8 1.7e-06 27.7 0.6 6.6 6 0 0 6 6 6 6 Domain of unknown function, DUF529 DEAD PF00270.24 EDO05503.1 - 3.1e-49 166.7 0.1 6.8e-48 162.3 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO05503.1 - 8.3e-23 80.0 0.0 2.7e-22 78.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO05503.1 - 0.00013 21.9 0.0 0.00036 20.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDO05503.1 - 0.0016 17.2 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4242 PF14026.1 EDO05503.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) LSM PF01423.17 EDO05504.1 - 3.6e-16 58.4 0.3 5.2e-16 57.9 0.2 1.2 1 0 0 1 1 1 1 LSM domain TPR_11 PF13414.1 EDO05505.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 TPR repeat V-SNARE_C PF12352.3 EDO05506.1 - 0.00039 20.4 8.0 0.001 19.1 1.0 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus NPV_P10 PF05531.7 EDO05506.1 - 0.00081 19.5 10.2 0.24 11.6 0.2 2.6 2 1 0 2 2 2 2 Nucleopolyhedrovirus P10 protein SNARE PF05739.14 EDO05506.1 - 0.00095 18.8 9.7 0.12 12.0 0.4 2.6 2 0 0 2 2 2 2 SNARE domain BLOC1_2 PF10046.4 EDO05506.1 - 0.0041 17.2 7.6 0.029 14.4 1.2 2.5 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec20 PF03908.8 EDO05506.1 - 0.015 14.9 3.6 0.015 14.9 2.5 2.3 2 1 0 2 2 2 0 Sec20 DUF769 PF05590.6 EDO05506.1 - 0.018 14.2 0.9 0.026 13.7 0.5 1.5 1 1 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) DASH_Dam1 PF08653.5 EDO05506.1 - 0.13 12.0 2.8 1.8 8.4 0.1 3.0 2 1 1 3 3 3 0 DASH complex subunit Dam1 Laminin_II PF06009.7 EDO05506.1 - 0.14 11.9 13.0 1.1 8.9 1.3 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF2392 PF10288.4 EDO05506.1 - 0.18 12.1 4.7 0.19 12.1 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2392) Muted PF14942.1 EDO05506.1 - 0.2 11.5 6.3 0.23 11.3 0.5 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF745 PF05335.8 EDO05506.1 - 0.26 10.7 9.3 0.67 9.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Vps5 PF09325.5 EDO05506.1 - 0.27 10.4 6.0 1 8.5 0.2 2.6 2 1 1 3 3 3 0 Vps5 C terminal like DUF1664 PF07889.7 EDO05506.1 - 0.41 10.4 10.8 1.8 8.3 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.7 EDO05506.1 - 0.41 10.8 8.3 5.6 7.1 1.6 2.6 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Sec34 PF04136.10 EDO05506.1 - 0.77 9.4 5.8 1.4 8.5 0.5 2.2 2 0 0 2 2 2 0 Sec34-like family PspB PF06667.7 EDO05506.1 - 0.85 9.5 3.7 2.1 8.3 0.7 2.3 2 0 0 2 2 2 0 Phage shock protein B DUF3508 PF12018.3 EDO05506.1 - 0.97 8.3 6.1 3.4 6.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3508) DUF2664 PF10867.3 EDO05506.1 - 1 9.9 7.3 1.3 9.7 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2664) Toxin_52 PF15605.1 EDO05506.1 - 1.2 9.0 5.6 4 7.3 0.2 2.6 2 1 0 2 2 2 0 Putative toxin 52 DASH_Duo1 PF08651.5 EDO05506.1 - 1.8 8.2 10.7 2.3 7.8 0.6 3.4 2 2 2 4 4 4 0 DASH complex subunit Duo1 DUF4446 PF14584.1 EDO05506.1 - 2 8.2 5.6 7.1 6.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF948 PF06103.6 EDO05506.1 - 2.2 8.1 11.5 0.22 11.4 2.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cauli_AT PF03233.8 EDO05506.1 - 5.3 6.7 10.3 1.7 8.3 0.6 2.3 1 1 1 2 2 2 0 Aphid transmission protein MCPsignal PF00015.16 EDO05506.1 - 6.2 6.2 14.0 2.5 7.5 1.6 2.2 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec8_exocyst PF04048.9 EDO05506.1 - 8.1 6.0 13.6 2.2 7.9 2.7 3.3 2 2 0 2 2 2 0 Sec8 exocyst complex component specific domain Peptidase_S26 PF10502.4 EDO05507.1 - 7.4e-08 32.0 0.0 6.3e-07 28.9 0.0 1.9 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 EDO05507.1 - 0.00077 19.0 0.3 0.0028 17.2 0.2 1.9 1 1 1 2 2 2 1 Peptidase S24-like ClpS PF02617.12 EDO05508.1 - 8.1e-15 54.3 0.4 2.4e-14 52.7 0.1 1.8 1 1 1 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS AP2 PF00847.15 EDO05509.1 - 1.4e-08 34.7 2.3 2.5e-08 33.9 1.6 1.4 1 0 0 1 1 1 1 AP2 domain OGG_N PF07934.7 EDO05510.1 - 1.2e-17 64.0 0.0 2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EDO05510.1 - 3.7e-09 36.8 0.0 5.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EDO05510.1 - 3.3e-07 29.6 0.0 1.2e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_2 PF12826.2 EDO05510.1 - 0.11 12.3 0.0 1.2 9.0 0.0 2.5 4 0 0 4 4 4 0 Helix-hairpin-helix motif CTP_transf_2 PF01467.21 EDO05511.1 - 1.7e-28 99.6 0.0 4.8e-15 55.9 0.0 2.5 2 1 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 EDO05511.1 - 1.2e-05 24.9 2.3 0.16 11.6 0.4 3.2 2 1 0 2 2 2 2 FAD synthetase CytoC_RC PF02276.13 EDO05513.1 - 0.03 13.4 0.0 0.045 12.8 0.0 1.1 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit PXT1 PF15214.1 EDO05513.1 - 0.086 13.1 1.3 15 5.9 0.1 2.9 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 HA2 PF04408.18 EDO05515.1 - 3.3e-24 84.8 0.0 6.4e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDO05515.1 - 2.6e-18 65.9 0.1 5.8e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EDO05515.1 - 3.7e-12 45.9 0.0 8.3e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO05515.1 - 2.3e-09 36.9 0.8 4.9e-09 35.9 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.9 EDO05515.1 - 6.9e-08 32.3 0.1 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_22 PF13401.1 EDO05515.1 - 0.00012 22.2 0.5 0.00072 19.7 0.0 2.5 3 1 0 3 3 2 1 AAA domain SRP54 PF00448.17 EDO05515.1 - 0.001 18.5 0.6 0.0035 16.7 0.4 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ABC_tran PF00005.22 EDO05515.1 - 0.0015 18.8 0.2 0.19 12.0 0.1 2.5 1 1 1 2 2 2 1 ABC transporter ResIII PF04851.10 EDO05515.1 - 0.0026 17.6 0.1 0.095 12.5 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit KaiC PF06745.8 EDO05515.1 - 0.0032 16.6 0.0 0.006 15.7 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_30 PF13604.1 EDO05515.1 - 0.0071 15.9 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EDO05515.1 - 0.0071 15.2 0.0 0.018 13.9 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 EDO05515.1 - 0.009 15.7 0.1 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase UPF0079 PF02367.12 EDO05515.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EDO05515.1 - 0.016 14.2 0.1 0.077 12.0 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EDO05515.1 - 0.038 13.7 0.9 0.098 12.4 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain PhoH PF02562.11 EDO05515.1 - 0.044 13.0 0.1 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein cobW PF02492.14 EDO05515.1 - 0.045 13.2 0.1 0.4 10.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zot PF05707.7 EDO05515.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_29 PF13555.1 EDO05515.1 - 0.053 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EDO05515.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EDO05515.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EDO05515.1 - 0.079 12.8 0.2 1.7 8.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EDO05515.1 - 0.12 11.3 0.1 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 EDO05515.1 - 0.13 12.5 0.1 0.52 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain zf-C3HC4_3 PF13920.1 EDO05518.1 - 4.1e-14 51.9 5.0 8.5e-14 50.9 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO05518.1 - 1.9e-08 34.2 9.7 4.3e-08 33.0 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO05518.1 - 1.2e-06 28.0 9.1 2.4e-06 27.1 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO05518.1 - 5.7e-06 26.0 9.3 1.2e-05 25.0 6.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EDO05518.1 - 5.3e-05 22.8 7.4 0.00012 21.7 5.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EDO05518.1 - 0.012 15.1 4.0 0.026 14.0 2.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EDO05518.1 - 0.024 14.3 2.1 0.22 11.2 1.5 2.3 1 1 1 2 2 2 0 RING-type zinc-finger PgaD PF13994.1 EDO05518.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein DZR PF12773.2 EDO05518.1 - 0.11 12.2 2.4 0.27 11.0 1.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon DUF1272 PF06906.6 EDO05518.1 - 0.34 10.7 4.7 0.9 9.4 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.1 EDO05518.1 - 0.47 10.3 11.6 0.066 13.0 4.4 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EDO05518.1 - 0.6 9.7 4.5 1.3 8.6 3.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ribosomal_L10 PF00466.15 EDO05519.1 - 6.3e-10 38.8 0.1 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 tRNA-synt_1d PF00750.14 EDO05520.1 - 3e-51 174.3 0.0 5.1e-27 94.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EDO05520.1 - 2.7e-16 59.5 0.6 5.1e-16 58.7 0.1 1.8 2 0 0 2 2 2 1 DALR anticodon binding domain Utp12 PF04003.7 EDO05521.1 - 4.5e-16 58.7 0.4 6.9e-16 58.1 0.3 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ribosomal_L36 PF00444.13 EDO05521.1 - 0.00056 19.8 0.1 0.0024 17.8 0.1 2.2 1 0 0 1 1 1 1 Ribosomal protein L36 CLTH PF10607.4 EDO05522.1 - 2.2e-20 72.8 0.9 2.2e-20 72.8 0.6 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Utp11 PF03998.8 EDO05523.1 - 3.1e-39 135.2 10.4 3.7e-39 135.0 7.2 1.1 1 0 0 1 1 1 1 Utp11 protein Alpha-2-MRAP_N PF06400.6 EDO05523.1 - 0.0097 15.5 0.9 0.018 14.7 0.6 1.4 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, N-terminal domain Dala_Dala_lig_N PF01820.16 EDO05523.1 - 0.044 14.1 0.9 0.12 12.6 0.0 2.1 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus MutS_V PF00488.16 EDO05524.1 - 3.2e-80 268.9 0.0 5.6e-80 268.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.15 EDO05524.1 - 4.1e-32 110.5 0.0 1.1e-31 109.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.13 EDO05524.1 - 3.1e-29 102.2 2.1 3.3e-29 102.1 0.4 1.9 2 0 0 2 2 2 1 MutS domain III NfeD PF01957.13 EDO05524.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding TPR_2 PF07719.12 EDO05525.1 - 1.1e-08 34.3 1.4 0.013 15.3 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDO05525.1 - 1.3e-08 34.3 3.6 0.36 10.5 0.0 6.3 6 1 2 8 8 8 2 TPR repeat SRP72 PF08492.7 EDO05525.1 - 2e-08 34.5 0.4 2e-08 34.5 0.3 2.1 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_14 PF13428.1 EDO05525.1 - 3e-05 24.2 0.0 0.057 14.0 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EDO05525.1 - 3.9e-05 23.7 10.3 0.01 15.9 0.6 5.1 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EDO05525.1 - 7.5e-05 22.9 0.0 0.11 12.9 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO05525.1 - 8e-05 23.2 0.0 0.64 10.7 0.0 4.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO05525.1 - 0.00023 20.6 0.6 1.2 9.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO05525.1 - 0.00044 20.1 3.1 0.42 10.5 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO05525.1 - 0.0018 18.6 0.1 16 6.1 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDO05525.1 - 0.0051 16.5 0.0 0.035 13.9 0.0 2.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDO05525.1 - 0.0064 16.0 2.1 2.9 7.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 EDO05525.1 - 0.022 15.1 0.0 0.41 11.2 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat NARP1 PF12569.3 EDO05525.1 - 0.1 11.3 0.0 0.82 8.3 0.0 2.3 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 Proteasome PF00227.21 EDO05526.1 - 2.5e-36 124.7 0.0 2.8e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PB1 PF00564.19 EDO05526.1 - 0.034 13.7 0.1 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 PB1 domain Band_7 PF01145.20 EDO05527.1 - 8.3e-26 90.9 0.6 1.3e-25 90.3 0.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Lactamase_B_2 PF12706.2 EDO05528.1 - 7.6e-12 45.1 0.0 9.9e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EDO05528.1 - 4.4e-06 26.4 0.0 9.7e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Vac_Fusion PF02346.11 EDO05528.1 - 0.17 11.3 0.2 0.38 10.2 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus fusion protein Cpn10 PF00166.16 EDO05529.1 - 6.9e-26 90.0 0.0 7.7e-26 89.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pro_isomerase PF00160.16 EDO05530.1 - 3.9e-21 75.8 0.0 4.8e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AhpC-TSA PF00578.16 EDO05531.1 - 4.3e-30 103.9 0.0 5.9e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EDO05531.1 - 4e-14 52.4 0.0 5.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EDO05531.1 - 1.6e-05 24.4 0.0 2.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.1 EDO05531.1 - 0.017 15.0 0.0 0.075 12.9 0.0 2.1 2 1 0 2 2 2 0 AhpC/TSA antioxidant enzyme VESA1_N PF12785.2 EDO05532.1 - 1.3e-17 63.9 13.6 1.3e-17 63.9 9.4 5.7 3 2 1 4 4 4 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05533.1 - 1.4e-218 726.4 20.9 1.4e-218 726.4 14.5 2.4 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 NPV_P10 PF05531.7 EDO05533.1 - 0.031 14.5 9.1 2.8 8.2 1.2 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein APG17 PF04108.7 EDO05533.1 - 0.07 11.9 2.9 0.12 11.1 2.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 Spectrin PF00435.16 EDO05533.1 - 0.11 12.8 6.8 0.048 13.9 1.0 2.5 2 0 0 2 2 2 0 Spectrin repeat Baculo_p24 PF05073.7 EDO05533.1 - 0.16 11.4 0.3 0.63 9.5 0.1 1.9 1 1 1 2 2 2 0 Baculovirus P24 capsid protein AAA_13 PF13166.1 EDO05533.1 - 0.46 8.8 3.6 0.87 7.9 2.5 1.3 1 0 0 1 1 1 0 AAA domain Acyl-CoA_dh_C PF12806.2 EDO05533.1 - 2.1 8.1 8.4 7 6.5 2.3 3.2 2 1 1 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like EntA_Immun PF08951.5 EDO05533.1 - 2.9 8.0 6.9 1.9 8.6 1.6 2.7 2 0 0 2 2 2 0 Enterocin A Immunity CK2S PF15011.1 EDO05533.1 - 3.5 7.3 5.3 4.4 7.0 1.4 2.7 2 1 0 2 2 2 0 Casein Kinase 2 substrate BACK PF07707.10 EDO05534.1 - 0.0099 15.6 0.0 0.058 13.2 0.0 2.2 2 1 0 2 2 2 1 BTB And C-terminal Kelch Telomere_Sde2 PF13019.1 EDO05536.1 - 1.1e-13 51.2 1.2 2.4e-13 50.0 0.8 1.6 1 0 0 1 1 1 1 Telomere stability and silencing SRP9-21 PF05486.7 EDO05536.1 - 0.097 12.4 0.1 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) PRELI PF04707.9 EDO05537.1 - 1.5e-09 37.6 0.2 1.7e-09 37.4 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family zf-CSL PF05207.8 EDO05538.1 - 8.8e-18 63.5 0.8 1.1e-17 63.2 0.6 1.2 1 0 0 1 1 1 1 CSL zinc finger zf-like PF04071.7 EDO05538.1 - 0.079 12.6 0.5 0.12 12.0 0.4 1.3 1 0 0 1 1 1 0 Cysteine-rich small domain MMR_HSR1 PF01926.18 EDO05539.1 - 1.5e-26 92.6 0.7 9.1e-20 70.7 0.0 2.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDO05539.1 - 2.2e-15 56.5 0.3 1.6e-09 37.5 0.0 3.5 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EDO05539.1 - 1.9e-11 43.4 0.1 6.8e-10 38.4 0.1 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EDO05539.1 - 6.9e-08 33.0 0.1 0.00052 20.4 0.0 2.6 3 0 0 3 3 3 2 Miro-like protein Dynamin_N PF00350.18 EDO05539.1 - 1.1e-07 31.8 0.5 0.0083 15.9 0.1 3.1 2 1 1 3 3 3 2 Dynamin family cobW PF02492.14 EDO05539.1 - 7.9e-06 25.4 0.1 3.1e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.11 EDO05539.1 - 2.8e-05 23.3 0.2 0.0085 15.2 0.0 2.2 2 0 0 2 2 2 2 AIG1 family Ras PF00071.17 EDO05539.1 - 8.1e-05 22.0 0.0 0.004 16.5 0.0 2.6 2 1 0 2 2 2 1 Ras family SRPRB PF09439.5 EDO05539.1 - 0.0072 15.5 0.3 0.11 11.7 0.0 2.5 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Ligase_CoA PF00549.14 EDO05539.1 - 0.013 15.0 0.7 0.095 12.3 0.0 2.4 3 0 0 3 3 3 0 CoA-ligase ABC_tran PF00005.22 EDO05539.1 - 0.02 15.2 0.1 0.035 14.3 0.1 1.6 1 1 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EDO05539.1 - 0.024 13.8 0.2 0.065 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Prenyltrans PF00432.16 EDO05541.1 - 9.9e-45 149.7 4.4 2e-13 49.6 0.1 5.5 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDO05541.1 - 4.3e-41 139.8 0.0 5.6e-22 78.2 0.0 3.8 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EDO05541.1 - 4.2e-10 39.6 0.0 0.00056 19.8 0.0 3.4 1 1 4 5 5 5 4 Prenyltransferase-like A2M_comp PF07678.9 EDO05541.1 - 0.15 11.2 0.0 8 5.6 0.0 2.5 2 0 0 2 2 2 0 A-macroglobulin complement component Pec_lyase PF09492.5 EDO05541.1 - 0.21 10.6 0.0 0.44 9.6 0.0 1.4 1 0 0 1 1 1 0 Pectic acid lyase SAC3_GANP PF03399.11 EDO05542.1 - 1.1e-37 129.5 4.5 2e-37 128.7 3.1 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Helicase_C_2 PF13307.1 EDO05543.1 - 1.9e-39 135.2 0.0 7e-39 133.4 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EDO05543.1 - 4.3e-35 120.6 1.2 8.2e-35 119.7 0.8 1.5 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 EDO05543.1 - 3e-06 26.8 0.0 0.0055 16.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EDO05543.1 - 0.0001 22.1 0.0 0.088 12.6 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDO05543.1 - 0.0073 15.1 0.0 0.018 13.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA PF00004.24 EDO05543.1 - 0.017 15.2 0.0 0.39 10.9 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO05543.1 - 0.027 14.6 0.0 3.5 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain ESCRT-II PF05871.7 EDO05544.1 - 1.4e-16 60.6 0.2 2.7e-14 53.2 0.1 2.7 1 1 1 2 2 2 1 ESCRT-II complex subunit DDRGK PF09756.4 EDO05545.1 - 2.8e-53 180.1 20.0 3.4e-53 179.8 13.8 1.1 1 0 0 1 1 1 1 DDRGK domain IncA PF04156.9 EDO05545.1 - 0.00036 20.1 11.0 0.00063 19.3 7.6 1.3 1 0 0 1 1 1 1 IncA protein Ycf1 PF05758.7 EDO05545.1 - 0.00061 17.6 10.3 0.00076 17.3 7.1 1.1 1 0 0 1 1 1 1 Ycf1 DUF1510 PF07423.6 EDO05545.1 - 0.0013 18.1 9.6 0.0018 17.6 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Mem_trans PF03547.13 EDO05545.1 - 0.0025 16.2 1.0 0.0026 16.0 0.7 1.1 1 0 0 1 1 1 1 Membrane transport protein Neur_chan_memb PF02932.11 EDO05545.1 - 0.012 15.4 0.2 0.013 15.3 0.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.7 EDO05545.1 - 0.016 15.1 7.7 0.035 14.0 5.5 1.5 2 0 0 2 2 1 0 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.5 EDO05545.1 - 0.082 12.6 16.9 2.2 8.0 3.1 2.1 1 1 1 2 2 2 0 Peptidase family S49 N-terminal His_Phos_2 PF00328.17 EDO05545.1 - 0.09 12.0 2.6 0.1 11.9 1.8 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Ribosomal_L18ae PF01775.12 EDO05545.1 - 0.14 12.0 4.0 0.2 11.5 2.8 1.2 1 0 0 1 1 1 0 Ribosomal L18ae/LX protein domain ETRAMP PF09716.5 EDO05545.1 - 0.16 11.9 0.5 0.71 9.8 0.3 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DDHD PF02862.12 EDO05545.1 - 0.19 11.4 6.7 0.3 10.8 4.6 1.3 1 0 0 1 1 1 0 DDHD domain DUF2756 PF10956.3 EDO05545.1 - 0.19 11.9 3.9 0.29 11.4 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) CAF-1_p150 PF11600.3 EDO05545.1 - 0.22 10.8 30.4 0.3 10.4 21.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Rgp1 PF08737.5 EDO05545.1 - 0.23 10.4 7.4 0.3 10.1 5.1 1.1 1 0 0 1 1 1 0 Rgp1 Apt1 PF10351.4 EDO05545.1 - 0.27 10.0 8.7 0.42 9.4 6.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_M3_N PF08439.5 EDO05545.1 - 0.28 11.2 8.7 0.26 11.3 4.3 2.1 2 0 0 2 2 2 0 Oligopeptidase F OmpH PF03938.9 EDO05545.1 - 0.37 10.7 19.5 0.51 10.2 13.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Vfa1 PF08432.5 EDO05545.1 - 0.55 10.2 17.6 2.5 8.1 12.0 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 eIF3_subunit PF08597.5 EDO05545.1 - 0.66 9.4 21.0 0.89 9.0 14.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CK_II_beta PF01214.13 EDO05545.1 - 1.7 8.1 5.2 2.2 7.7 2.5 1.9 1 1 1 2 2 2 0 Casein kinase II regulatory subunit LMBR1 PF04791.11 EDO05545.1 - 2.3 6.7 4.3 3.3 6.1 2.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_11 PF13086.1 EDO05545.1 - 3.8 7.0 11.3 6 6.3 7.8 1.3 1 0 0 1 1 1 0 AAA domain DUF4557 PF15101.1 EDO05545.1 - 4.2 7.1 9.8 6.7 6.4 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CagX PF03524.10 EDO05545.1 - 4.6 6.4 7.4 11 5.1 5.1 1.7 1 1 0 1 1 1 0 Conjugal transfer protein SID-1_RNA_chan PF13965.1 EDO05545.1 - 6 4.8 6.2 11 4.0 4.3 1.5 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 PolyA_pol PF01743.15 EDO05546.1 - 1.4e-27 96.3 0.1 3.3e-27 95.1 0.1 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EDO05546.1 - 0.00066 19.1 0.2 0.0017 17.9 0.0 1.7 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A DUF4222 PF13973.1 EDO05547.1 - 0.12 11.8 0.7 0.23 10.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4222) zf-DHHC PF01529.15 EDO05549.1 - 1.1e-27 96.4 16.7 1.4e-27 96.2 11.6 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF3112 PF11309.3 EDO05549.1 - 0.022 14.5 7.6 0.05 13.4 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) Pkinase PF00069.20 EDO05550.1 - 4.8e-65 219.2 0.0 1.4e-64 217.7 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.24 EDO05550.1 - 1.7e-63 210.3 0.8 3.3e-19 68.5 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 EDO05550.1 - 3.3e-29 101.7 0.0 5.6e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO05550.1 - 5.1e-06 25.6 0.0 1.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Cupin_2 PF07883.6 EDO05550.1 - 0.00015 21.1 1.5 1.2 8.6 0.0 3.8 4 0 0 4 4 4 2 Cupin domain Kdo PF06293.9 EDO05550.1 - 0.0033 16.5 0.0 0.0068 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO05550.1 - 0.0084 15.8 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Zip PF02535.17 EDO05552.1 - 4.2e-17 62.1 8.4 5.2e-17 61.8 5.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DctQ PF04290.7 EDO05552.1 - 0.0044 16.7 3.9 0.0082 15.8 2.3 1.7 1 1 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component Cyt-b5 PF00173.23 EDO05553.1 - 8e-25 86.4 0.0 9.4e-25 86.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CotJB PF12652.2 EDO05553.1 - 0.11 12.5 0.3 2.2 8.4 0.0 2.2 1 1 1 2 2 2 0 CotJB protein Ribosomal_L3 PF00297.17 EDO05554.1 - 7.1e-28 97.7 0.4 6.3e-27 94.6 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L3 RRM_1 PF00076.17 EDO05555.1 - 3.7e-13 48.8 0.0 4.7e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO05555.1 - 1e-09 38.1 0.0 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO05555.1 - 0.0091 15.7 0.0 0.035 13.8 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EDO05555.1 - 0.016 15.0 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO05556.1 - 1.2e-14 53.7 0.0 2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO05556.1 - 4.5e-11 42.5 0.0 8.1e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO05556.1 - 2.5e-06 27.2 0.0 5.5e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M9 PF01752.12 EDO05556.1 - 0.017 14.0 2.3 0.024 13.5 1.6 1.1 1 0 0 1 1 1 0 Collagenase Nup35_RRM_2 PF14605.1 EDO05556.1 - 0.069 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Use1 PF09753.4 EDO05556.1 - 0.55 9.6 8.1 0.74 9.2 5.5 1.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 LSM PF01423.17 EDO05557.1 - 4.7e-10 38.8 0.0 6.7e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain Feld-I_B PF09252.5 EDO05557.1 - 0.018 14.9 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Allergen Fel d I-B chain Telomerase_RBD PF12009.3 EDO05561.1 - 3.5e-29 101.4 0.7 3.5e-29 101.4 0.5 2.2 3 0 0 3 3 3 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EDO05561.1 - 2.1e-09 37.0 0.0 3.4e-06 26.5 0.0 2.7 2 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Leader_Trp PF08255.6 EDO05561.1 - 0.086 12.5 0.9 0.35 10.6 0.6 2.1 1 0 0 1 1 1 0 Trp-operon Leader Peptide Macro PF01661.16 EDO05562.1 - 3.1e-05 23.8 0.0 9e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Macro domain Nckap1 PF09735.4 EDO05562.1 - 0.096 10.1 0.0 0.13 9.6 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Peptidase_S39 PF02122.10 EDO05562.1 - 0.1 11.8 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Peptidase S39 DUF1129 PF06570.6 EDO05563.1 - 0.062 12.5 0.0 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) FYVE PF01363.16 EDO05564.1 - 0.43 10.5 9.9 0.04 13.8 3.6 1.7 2 0 0 2 2 2 0 FYVE zinc finger zf-Sec23_Sec24 PF04810.10 EDO05564.1 - 0.44 10.1 9.7 0.16 11.5 3.3 2.7 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger LIM PF00412.17 EDO05564.1 - 1.2 9.2 8.4 0.93 9.6 1.9 3.1 1 1 2 3 3 3 0 LIM domain C1_1 PF00130.17 EDO05564.1 - 2 8.2 10.5 0.9 9.3 5.3 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OTT_1508_deam PF14441.1 EDO05564.1 - 5.9 6.6 9.3 64 3.3 5.5 3.0 2 1 1 3 3 3 0 OTT_1508-like deaminase Sdh5 PF03937.11 EDO05565.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase AP2 PF00847.15 EDO05566.1 - 7e-36 122.1 15.8 6.2e-13 48.6 0.3 3.3 3 0 0 3 3 3 3 AP2 domain DUF2389 PF09493.5 EDO05566.1 - 0.00086 19.5 0.0 2.6 8.3 0.0 3.3 3 0 0 3 3 3 2 Tryptophan-rich protein (DUF2389) Rubredoxin PF00301.15 EDO05567.1 - 5e-05 23.0 1.9 0.00022 21.0 1.3 1.9 1 1 0 1 1 1 1 Rubredoxin DUF164 PF02591.10 EDO05567.1 - 0.00087 19.0 0.1 0.0022 17.7 0.0 1.7 1 0 0 1 1 1 1 Putative zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EDO05567.1 - 0.0012 18.6 0.4 0.17 11.7 0.1 2.3 2 0 0 2 2 2 1 Transposase zinc-ribbon domain DUF1610 PF07754.6 EDO05567.1 - 0.0039 17.2 4.7 0.018 15.1 0.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1610) zf-Mss51 PF13824.1 EDO05567.1 - 0.0066 16.2 1.8 0.85 9.5 0.0 2.2 1 1 1 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.1 EDO05567.1 - 0.034 13.3 0.4 0.034 13.3 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DUF2296 PF10058.4 EDO05567.1 - 0.053 13.2 0.5 2.8 7.7 0.1 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) OrfB_Zn_ribbon PF07282.6 EDO05567.1 - 0.059 13.0 2.3 0.68 9.6 0.1 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-nanos PF05741.8 EDO05567.1 - 0.07 13.1 0.6 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Nanos RNA binding domain TFIIS_C PF01096.13 EDO05567.1 - 0.074 12.6 1.4 6.9 6.3 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) HypA PF01155.14 EDO05567.1 - 0.12 12.0 0.7 0.22 11.2 0.2 1.6 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF35_N PF12172.3 EDO05567.1 - 0.28 11.1 3.8 2.9 7.9 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn-ribbon_8 PF09723.5 EDO05567.1 - 0.5 10.3 4.3 2.4 8.1 3.0 2.0 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 EDO05567.1 - 0.61 9.6 4.2 0.55 9.7 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.8 EDO05567.1 - 0.62 9.8 2.4 1.2 8.9 0.3 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like TF_Zn_Ribbon PF08271.7 EDO05567.1 - 5.6 6.3 6.1 1.4 8.3 0.3 2.1 1 1 0 2 2 2 0 TFIIB zinc-binding Ribonuc_red_lgC PF02867.10 EDO05568.1 - 2.1e-215 716.3 0.0 2.9e-215 715.9 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EDO05568.1 - 1.4e-22 79.2 0.0 3.8e-22 77.8 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EDO05568.1 - 1.6e-11 44.4 0.0 4.9e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 EDO05568.1 - 0.0056 14.8 0.0 0.0089 14.1 0.0 1.2 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase L27_1 PF09058.5 EDO05570.1 - 0.044 13.6 0.0 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 L27_1 Gemin7 PF11095.3 EDO05571.1 - 0.1 12.3 0.1 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) HIT PF01230.18 EDO05572.1 - 8.5e-21 74.3 0.1 1.5e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EDO05572.1 - 5.6e-07 29.7 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3080 PF11279.3 EDO05572.1 - 0.054 12.6 0.0 0.066 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) DUF3653 PF12375.3 EDO05572.1 - 0.088 13.0 0.0 3.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Phage protein Glyco_hydro_2 PF00703.16 EDO05572.1 - 0.12 12.8 0.1 0.24 11.8 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 2 zinc_ribbon_6 PF14599.1 EDO05572.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon DEAD PF00270.24 EDO05573.1 - 7.2e-42 142.7 0.0 2.3e-41 141.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO05573.1 - 2.5e-24 84.9 0.0 9.9e-24 83.0 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EDO05573.1 - 0.0012 18.9 0.1 0.096 12.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain RCC1 PF00415.13 EDO05574.1 - 3.5e-33 113.5 17.7 7.6e-12 45.2 0.0 5.3 5 1 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDO05574.1 - 1.5e-09 37.2 29.9 1.6e-05 24.4 1.7 5.5 4 2 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EDO05575.1 - 1e-61 204.9 24.9 4.8e-13 49.0 0.1 12.0 11 1 0 11 11 11 10 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDO05575.1 - 3.8e-30 102.8 52.0 6.8e-07 28.7 0.1 9.9 10 0 0 10 10 10 9 Regulator of chromosome condensation (RCC1) repeat YbfN PF13982.1 EDO05575.1 - 0.13 12.4 0.2 0.38 10.9 0.1 1.7 1 0 0 1 1 1 0 YbfN-like lipoprotein TPT PF03151.11 EDO05576.1 - 7.1e-33 113.4 26.0 3.4e-29 101.4 7.7 2.2 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EDO05576.1 - 2.9e-12 46.7 34.8 7.4e-09 35.7 8.8 2.8 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 EDO05576.1 - 1.3e-07 30.8 22.6 3.8e-07 29.3 15.6 1.7 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EDO05577.1 - 5.8e-28 97.4 19.9 2.4e-26 92.2 4.1 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EDO05577.1 - 1.3e-13 51.1 22.0 2.4e-08 34.0 6.5 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EDO05577.1 - 0.0023 16.9 18.2 0.084 11.7 12.6 2.5 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EDO05577.1 - 0.012 14.6 2.7 0.63 9.0 0.2 2.3 2 0 0 2 2 2 0 Nucleotide-sugar transporter EmrE PF13536.1 EDO05577.1 - 6.1 7.0 23.0 1.1 9.4 6.5 3.4 2 2 1 3 3 3 0 Multidrug resistance efflux transporter TPT PF03151.11 EDO05578.1 - 2.6e-28 98.6 28.3 3e-27 95.1 7.2 2.4 2 1 1 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 EDO05578.1 - 9.9e-11 41.7 28.0 6.3e-07 29.4 8.2 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EDO05578.1 - 6.9e-06 25.1 20.8 4.6e-05 22.4 3.8 2.5 2 1 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.10 EDO05578.1 - 0.00029 20.0 5.0 0.068 12.2 0.2 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter Pyr_redox_2 PF07992.9 EDO05579.1 - 3.4e-22 79.3 0.0 4.8e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO05579.1 - 2.3e-07 31.1 0.1 1.5e-06 28.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO05579.1 - 0.002 18.1 0.0 0.12 12.4 0.0 2.9 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.2 EDO05580.1 - 9.6e-18 64.3 0.8 8.7e-15 54.8 0.1 3.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDO05580.1 - 1.1e-15 56.5 5.1 7.1e-08 31.8 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EDO05580.1 - 3.6e-14 52.8 4.0 5.2e-08 33.2 0.1 5.1 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO05580.1 - 2.2e-13 49.0 0.2 0.0056 16.8 0.0 5.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EDO05580.1 - 1.4e-09 37.8 1.1 5.3e-05 23.3 0.1 4.6 3 1 2 5 5 5 2 Ankyrin repeats (many copies) GRDA PF04723.9 EDO05580.1 - 0.42 10.3 3.2 2.5 7.7 0.2 2.4 2 0 0 2 2 2 0 Glycine reductase complex selenoprotein A DUF2183 PF09949.4 EDO05581.1 - 3.4e-06 26.9 0.0 7.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) RLL PF10036.4 EDO05582.1 - 1.8e-05 24.3 0.0 1.8e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Putative carnitine deficiency-associated protein Trp_repressor PF01371.14 EDO05583.1 - 0.054 13.4 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 Trp repressor protein DNA_topoisoIV PF00521.15 EDO05583.1 - 0.12 11.2 0.6 0.18 10.6 0.4 1.3 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Sld5 PF05916.6 EDO05584.1 - 6.2e-06 26.4 0.0 9.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein MFS_1 PF07690.11 EDO05585.1 - 4e-16 58.6 21.5 4e-16 58.6 14.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UQ_con PF00179.21 EDO05586.1 - 3.1e-41 140.1 0.0 3.5e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO05586.1 - 0.0083 15.8 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UQ_con PF00179.21 EDO05587.1 - 3.1e-41 140.1 0.0 3.5e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO05587.1 - 0.0083 15.8 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B MFS_1 PF07690.11 EDO05588.1 - 4e-16 58.6 21.5 4e-16 58.6 14.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sld5 PF05916.6 EDO05589.1 - 6.2e-06 26.4 0.0 9.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Elf1 PF05129.8 EDO05590.1 - 7.4e-22 76.8 1.3 7.4e-22 76.8 0.9 1.6 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like Trp_repressor PF01371.14 EDO05591.1 - 0.06 13.2 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Trp repressor protein VESA1_N PF12785.2 EDO05592.1 - 6.5e-160 533.0 11.0 6.5e-160 533.0 7.6 3.2 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 DDE_Tnp_1_assoc PF13808.1 EDO05592.1 - 0.022 14.3 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 DDE_Tnp_1-associated WEMBL PF05701.6 EDO05592.1 - 0.032 12.7 11.3 0.1 11.0 7.7 1.7 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Spc7 PF08317.6 EDO05592.1 - 0.13 10.9 7.8 0.34 9.5 5.4 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF892 PF05974.7 EDO05592.1 - 0.14 11.9 1.8 0.4 10.4 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF892) TBCA PF02970.11 EDO05592.1 - 0.15 12.1 3.3 0.49 10.5 2.3 1.9 1 0 0 1 1 1 0 Tubulin binding cofactor A VESA1_N PF12785.2 EDO05594.1 - 7e-17 61.5 42.4 8.2e-11 41.5 0.0 5.4 4 1 1 5 5 5 3 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05595.1 - 1.4e-216 719.9 21.1 1.4e-216 719.9 14.6 2.4 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 IncA PF04156.9 EDO05595.1 - 0.0058 16.2 2.2 0.0089 15.6 0.1 2.0 2 0 0 2 2 2 1 IncA protein Spectrin PF00435.16 EDO05595.1 - 0.0058 16.8 3.3 0.0058 16.8 2.3 2.5 2 0 0 2 2 2 1 Spectrin repeat BAR_2 PF10455.4 EDO05595.1 - 0.02 13.8 7.2 0.66 8.8 2.0 2.2 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking NPV_P10 PF05531.7 EDO05595.1 - 0.024 14.8 10.7 2 8.7 1.1 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein APG17 PF04108.7 EDO05595.1 - 0.028 13.2 3.7 0.049 12.4 2.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 Senescence PF06911.7 EDO05595.1 - 0.062 12.9 8.9 2.8 7.6 4.4 3.1 2 1 0 2 2 2 0 Senescence-associated protein Baculo_p24 PF05073.7 EDO05595.1 - 0.071 12.6 0.5 0.21 11.1 0.2 1.9 1 1 1 2 2 2 0 Baculovirus P24 capsid protein AAA_27 PF13514.1 EDO05595.1 - 0.14 9.7 5.7 0.22 9.1 3.9 1.2 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 EDO05595.1 - 0.31 9.4 5.5 0.59 8.5 3.8 1.3 1 0 0 1 1 1 0 AAA domain Herpes_U30 PF04523.8 EDO05595.1 - 0.33 8.3 0.3 0.82 7.0 0.1 1.4 1 1 0 1 1 1 0 Herpes virus tegument protein U30 CAGE1 PF15066.1 EDO05595.1 - 0.83 8.0 8.6 0.22 9.9 0.2 2.2 2 0 0 2 2 2 0 Cancer-associated gene protein 1 family Transposase_22 PF02994.9 EDO05595.1 - 1.1 7.7 5.5 1.9 6.8 3.8 1.3 1 0 0 1 1 1 0 L1 transposable element V_ATPase_I PF01496.14 EDO05595.1 - 1.6 6.4 2.3 2.8 5.7 1.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IFT57 PF10498.4 EDO05595.1 - 2.3 6.9 8.2 0.33 9.6 0.7 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Acyl-CoA_dh_C PF12806.2 EDO05595.1 - 2.6 7.9 9.1 7 6.5 2.3 3.4 2 1 1 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like TPR_MLP1_2 PF07926.7 EDO05595.1 - 4.6 7.0 12.5 50 3.6 8.7 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 EDO05595.1 - 4.6 7.0 9.2 18 5.1 2.3 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CK2S PF15011.1 EDO05595.1 - 5.3 6.8 6.5 6.1 6.6 2.1 2.7 2 1 0 2 2 2 0 Casein Kinase 2 substrate EntA_Immun PF08951.5 EDO05595.1 - 6.1 7.0 8.9 3.4 7.8 2.7 2.9 2 1 1 3 3 2 0 Enterocin A Immunity F-box-like_2 PF13013.1 EDO05596.1 - 0.00058 19.5 0.4 0.33 10.6 0.0 2.3 2 0 0 2 2 2 2 F-box-like domain DUF3989 PF13150.1 EDO05597.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) VESA1_N PF12785.2 EDO05598.1 - 5.2e-21 75.1 27.6 7.2e-20 71.3 8.6 3.7 2 1 1 3 3 3 2 Variant erythrocyte surface antigen-1 RBP_receptor PF14752.1 EDO05598.1 - 0.029 12.7 0.1 0.21 9.8 0.0 2.0 2 0 0 2 2 2 0 Retinol binding protein receptor DUF3989 PF13150.1 EDO05598.1 - 0.049 13.0 0.0 8.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) DUF308 PF03729.8 EDO05598.1 - 0.31 11.0 10.6 2.4 8.2 0.4 3.3 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) CBF_beta PF02312.12 EDO05598.1 - 0.33 10.5 0.0 0.57 9.7 0.0 1.3 1 0 0 1 1 1 0 Core binding factor beta subunit DUF2956 PF11169.3 EDO05598.1 - 0.82 9.6 6.0 11 6.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) DUF2530 PF10745.4 EDO05598.1 - 5.3 7.0 8.1 19 5.2 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) VESA1_N PF12785.2 EDO05599.1 - 1.3e-215 716.7 22.4 1.3e-215 716.7 15.5 2.3 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 Baculo_PEP_C PF04513.7 EDO05599.1 - 0.1 12.4 1.2 0.6 9.9 0.1 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.1 EDO05599.1 - 0.17 11.1 0.5 0.46 9.7 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Syndecan PF01034.15 EDO05599.1 - 0.19 11.4 0.1 0.4 10.3 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain VESA1_N PF12785.2 EDO05600.1 - 1.4e-214 713.2 17.1 1.4e-214 713.2 11.9 2.8 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 HisKA_3 PF07730.8 EDO05600.1 - 0.046 14.0 0.0 4.4 7.7 0.0 2.9 2 0 0 2 2 2 0 Histidine kinase WEMBL PF05701.6 EDO05600.1 - 0.055 11.9 6.1 0.098 11.0 4.2 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Baculo_PEP_C PF04513.7 EDO05600.1 - 0.064 13.0 0.7 0.58 9.9 0.1 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PuR_N PF09182.5 EDO05600.1 - 0.22 11.1 0.0 0.49 10.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal DUF1664 PF07889.7 EDO05600.1 - 0.24 11.2 5.3 2.6 7.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Tic20 PF09685.5 EDO05601.1 - 0.00041 20.2 2.7 0.00082 19.3 1.8 1.5 1 0 0 1 1 1 1 Tic20-like protein DUF2207 PF09972.4 EDO05601.1 - 0.056 12.0 0.2 0.062 11.8 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF912 PF06024.7 EDO05602.1 - 0.28 11.2 0.2 0.28 11.2 0.1 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Baculo_11_kDa PF06143.6 EDO05602.1 - 3 7.2 9.6 2.1 7.7 0.2 3.3 3 0 0 3 3 3 0 Baculovirus 11 kDa family DUF2929 PF11151.3 EDO05602.1 - 8.2 6.5 11.3 3.8 7.6 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2929) SIT PF15330.1 EDO05602.1 - 9.4 6.4 10.5 30 4.8 0.2 3.4 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT VESA1_N PF12785.2 EDO05603.1 - 3.2e-12 46.1 2.9 1.3e-07 31.0 0.2 2.1 1 1 1 2 2 2 2 Variant erythrocyte surface antigen-1 F-box-like_2 PF13013.1 EDO05604.1 - 0.0017 18.0 0.0 0.0042 16.7 0.0 1.6 2 0 0 2 2 2 1 F-box-like domain CytochromB561_N PF09786.4 EDO05605.1 - 0.017 13.6 4.0 0.028 12.9 2.8 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal Herpes_UL45 PF05473.7 EDO05605.1 - 0.32 10.3 6.5 9.3 5.6 0.2 3.4 3 0 0 3 3 3 0 UL45 protein VESA1_N PF12785.2 EDO05606.1 - 3.6e-156 520.7 15.8 3.6e-156 520.7 11.0 2.1 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 LMP PF04778.7 EDO05606.1 - 0.31 10.7 3.5 0.19 11.4 0.2 2.0 2 0 0 2 2 2 0 LMP repeated region DUF2418 PF10332.4 EDO05610.1 - 0.15 12.3 0.0 0.15 12.3 0.0 3.4 5 1 0 5 5 5 0 Protein of unknown function (DUF2418) GRIM-19 PF06212.7 EDO05611.1 - 0.94 9.1 2.7 3.8 7.2 0.7 2.8 2 1 0 2 2 2 0 GRIM-19 protein RNase_PH PF01138.16 EDO05612.1 - 3e-19 69.6 0.0 3.8e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF3157 PF11355.3 EDO05612.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) Aldo_ket_red PF00248.16 EDO05613.1 - 4.8e-68 229.0 0.0 7e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family NIF PF03031.13 EDO05615.1 - 3.4e-24 85.3 0.7 6.5e-24 84.4 0.5 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.21 EDO05615.1 - 0.015 15.4 0.0 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Metallophos PF00149.23 EDO05616.1 - 4.8e-37 127.2 0.0 7.6e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EDO05616.1 - 6.1e-17 61.0 6.1 7.5e-10 38.3 0.2 3.1 2 1 1 3 3 3 2 TPR repeat PPP5 PF08321.7 EDO05616.1 - 3.6e-15 55.7 0.2 1.3e-08 34.7 0.0 2.7 2 0 0 2 2 2 2 PPP5 TPR repeat region TPR_1 PF00515.23 EDO05616.1 - 1.2e-09 37.3 4.5 3.6e-05 23.1 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO05616.1 - 8e-08 31.6 4.3 0.017 14.9 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDO05616.1 - 0.00074 19.1 0.3 0.075 12.8 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 EDO05616.1 - 0.0018 18.0 0.0 0.0045 16.8 0.0 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.1 EDO05616.1 - 0.0029 17.5 1.0 5.7 6.9 0.3 3.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDO05616.1 - 0.12 12.5 0.3 1.8 8.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin PF00085.15 EDO05617.1 - 5.4e-06 26.0 0.1 7.7e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EDO05617.1 - 1.4e-05 23.9 0.0 1.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Phosducin Ribosomal_S8e PF01201.17 EDO05619.1 - 4.7e-51 172.3 0.1 5.7e-51 172.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e VESA1_N PF12785.2 EDO05620.1 - 5.6e-12 45.3 12.4 5.9e-07 28.8 3.3 2.1 1 1 1 2 2 2 2 Variant erythrocyte surface antigen-1 BRX_N PF13713.1 EDO05620.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain DUF3638 PF12340.3 EDO05622.1 - 1.4e-18 66.7 0.5 3.7e-18 65.3 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EDO05622.1 - 1e-16 59.7 0.1 2.2e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF946 PF06101.6 EDO05622.1 - 5e-07 28.0 0.0 8.4e-07 27.3 0.0 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) EF-hand_7 PF13499.1 EDO05622.1 - 0.018 15.1 0.0 11 6.2 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain pair Cpn60_TCP1 PF00118.19 EDO05623.1 - 3.1e-153 510.8 0.2 3.7e-153 510.6 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ATP12 PF07542.6 EDO05624.1 - 3.2e-05 23.8 0.0 6.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 ATP12 chaperone protein SIS PF01380.17 EDO05625.1 - 1.3e-32 112.1 2.2 1.5e-15 56.9 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 EDO05625.1 - 5.3e-17 62.0 0.0 1.3e-16 60.7 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EDO05625.1 - 2.7e-15 55.9 0.2 5.4e-12 45.1 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 EDO05625.1 - 5.5e-10 39.0 0.0 2.1e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EDO05625.1 - 0.00016 20.4 0.0 0.0003 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II EF-hand_4 PF12763.2 EDO05626.1 - 5.1e-17 61.5 0.3 3.4e-07 29.9 0.1 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EDO05626.1 - 2e-11 43.8 6.8 5.6e-09 36.0 1.3 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EDO05626.1 - 2.7e-10 38.7 1.9 0.046 13.0 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EDO05626.1 - 1.1e-05 24.8 4.2 0.022 14.6 0.1 4.3 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.1 EDO05626.1 - 0.00021 20.8 3.8 0.5 10.0 0.1 3.7 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EDO05626.1 - 0.00065 18.9 0.5 2.8 7.4 0.0 3.5 3 0 0 3 3 3 2 EF hand TSC22 PF01166.13 EDO05626.1 - 0.03 14.2 9.6 0.057 13.3 0.9 3.0 2 0 0 2 2 2 0 TSC-22/dip/bun family Spc7 PF08317.6 EDO05626.1 - 0.053 12.1 15.3 0.093 11.3 10.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 EDO05626.1 - 0.13 11.1 11.6 0.21 10.5 8.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_TATA_bd PF12325.3 EDO05626.1 - 0.13 11.9 23.0 0.044 13.5 2.7 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 EDO05626.1 - 0.17 11.7 23.9 0.095 12.5 3.7 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EDO05626.1 - 0.19 11.3 14.5 0.32 10.5 10.0 1.5 1 0 0 1 1 1 0 IncA protein Peptidase_C98 PF15499.1 EDO05626.1 - 0.2 10.8 3.0 0.5 9.6 2.1 1.6 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DivIC PF04977.10 EDO05626.1 - 0.6 9.6 12.9 0.77 9.2 0.7 2.5 1 1 0 2 2 2 0 Septum formation initiator AAA_23 PF13476.1 EDO05626.1 - 0.64 10.3 3.9 0.9 9.8 2.7 1.3 1 0 0 1 1 1 0 AAA domain FUSC PF04632.7 EDO05626.1 - 0.92 7.8 8.8 1.3 7.4 6.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ly49 PF08391.5 EDO05626.1 - 1.4 9.0 6.7 4.2 7.5 4.7 1.8 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region ADIP PF11559.3 EDO05626.1 - 3.1 7.7 21.7 0.18 11.7 11.0 1.9 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.1 EDO05626.1 - 6.3 7.2 10.9 8.6 6.8 3.1 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Shugoshin_N PF07558.6 EDO05626.1 - 9.5 6.0 9.2 0.29 10.8 0.1 2.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.10 EDO05626.1 - 9.7 6.1 17.2 0.49 10.2 1.3 3.1 1 1 2 3 3 3 0 Basic region leucine zipper RRM_1 PF00076.17 EDO05627.1 - 4.7e-38 128.6 5.0 3.7e-16 58.5 0.0 6.4 7 0 0 7 7 7 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO05627.1 - 4.5e-29 100.2 2.8 1.1e-12 47.7 0.0 5.5 5 1 0 5 5 5 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO05627.1 - 5.7e-17 61.3 4.5 6.1e-06 25.9 0.0 4.9 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDO05627.1 - 0.00027 20.6 1.0 0.34 10.6 0.0 4.4 5 0 0 5 5 5 2 Limkain b1 Cgr1 PF03879.9 EDO05628.1 - 0.11 12.7 23.9 0.24 11.5 16.5 1.5 1 1 0 1 1 1 0 Cgr1 family GIDA_assoc_3 PF13932.1 EDO05628.1 - 0.94 9.5 5.8 1.6 8.8 1.8 2.4 1 1 1 2 2 2 0 GidA associated domain 3 SpoU_sub_bind PF08032.7 EDO05628.1 - 2.9 8.1 6.2 50 4.1 4.3 2.2 1 1 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding DUF2514 PF10721.4 EDO05628.1 - 7 6.3 14.9 11 5.6 10.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) DUF883 PF05957.8 EDO05628.1 - 7.7 6.9 9.3 11 6.5 5.3 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) MtrH PF02007.13 EDO05629.1 - 0.08 11.9 0.2 3.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit Big_3_2 PF12245.3 EDO05629.1 - 0.088 12.3 0.0 2.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DER1 PF04511.10 EDO05630.1 - 8.8e-34 116.7 9.2 1.1e-33 116.4 6.4 1.1 1 0 0 1 1 1 1 Der1-like family Peptidase_M48 PF01435.13 EDO05631.1 - 1.1e-41 142.8 0.1 1.9e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 DUF1634 PF07843.6 EDO05631.1 - 0.0052 16.4 4.3 0.015 14.9 3.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1634) DUF1144 PF06610.8 EDO05631.1 - 0.0061 16.3 1.5 0.009 15.7 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1144) MARVEL PF01284.18 EDO05631.1 - 1.1 9.0 12.6 1.8 8.3 0.0 3.1 3 0 0 3 3 3 0 Membrane-associating domain Proteasome PF00227.21 EDO05632.1 - 4.5e-49 166.3 1.0 5.4e-49 166.0 0.7 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO05632.1 - 3.4e-14 51.8 0.0 6.1e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2207 PF09972.4 EDO05633.1 - 0.02 13.4 0.2 0.025 13.1 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4519 PF15012.1 EDO05633.1 - 0.048 13.5 0.2 0.091 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Got1 PF04178.7 EDO05633.1 - 0.071 13.2 0.3 0.071 13.2 0.2 1.6 2 0 0 2 2 2 0 Got1/Sft2-like family DUF1358 PF07096.6 EDO05633.1 - 0.095 12.3 0.1 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) Tic20 PF09685.5 EDO05633.1 - 0.3 11.0 2.2 0.7 9.8 0.2 2.0 2 0 0 2 2 2 0 Tic20-like protein Cation_ATPase_C PF00689.16 EDO05634.1 - 0.54 9.7 29.3 0.05 13.1 6.3 3.1 1 1 2 3 3 3 0 Cation transporting ATPase, C-terminus VESA1_N PF12785.2 EDO05635.1 - 1.3e-10 40.8 10.4 7e-07 28.5 0.3 2.2 1 1 1 2 2 2 2 Variant erythrocyte surface antigen-1 Ad_cyc_g-alpha PF08509.6 EDO05636.1 - 0.00093 18.4 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain OPA3 PF07047.7 EDO05638.1 - 7.2e-41 139.0 0.0 8.5e-41 138.8 0.0 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) GTP_EFTU PF00009.22 EDO05639.1 - 1.3e-07 31.2 2.5 0.0033 16.8 0.0 3.4 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO05639.1 - 1.2e-06 28.4 0.5 1.6e-05 24.8 0.1 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDO05639.1 - 0.0012 18.7 0.0 0.074 12.8 0.0 2.6 2 0 0 2 2 2 1 Dynamin family PduV-EutP PF10662.4 EDO05639.1 - 0.0042 16.5 0.0 0.057 12.9 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EDO05639.1 - 0.022 13.9 0.1 0.048 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDO05639.1 - 0.041 13.8 0.0 0.099 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 EDO05639.1 - 0.075 12.7 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EDO05639.1 - 0.11 11.8 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.24 EDO05640.1 - 1.2e-26 93.1 0.0 2.3e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO05640.1 - 8.2e-21 73.6 0.1 2.2e-20 72.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EDO05640.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain TPR_19 PF14559.1 EDO05643.1 - 1.2e-16 60.7 10.9 0.0018 18.5 0.1 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDO05643.1 - 2.7e-14 53.3 5.6 5.9e-05 23.6 0.0 8.4 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDO05643.1 - 1.6e-13 49.9 0.1 0.0026 18.2 0.0 8.7 7 2 2 9 9 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO05643.1 - 2.4e-08 33.2 24.1 0.028 14.3 0.0 10.7 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_11 PF13414.1 EDO05643.1 - 1.3e-06 27.9 31.5 0.0018 17.8 0.1 9.2 10 1 1 11 11 11 3 TPR repeat TPR_17 PF13431.1 EDO05643.1 - 8.2e-05 22.5 4.3 17 5.9 0.0 7.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDO05643.1 - 0.0017 18.6 8.8 0.049 14.1 0.1 4.6 5 0 0 5 5 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EDO05643.1 - 0.0029 17.7 0.4 0.0029 17.7 0.3 5.9 6 3 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EDO05643.1 - 0.038 13.7 8.6 43 4.2 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO05643.1 - 1 9.1 17.6 15 5.4 0.2 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO05643.1 - 5 7.1 30.7 0.4 10.6 0.1 8.5 9 2 1 10 10 10 0 Tetratricopeptide repeat RAP PF08373.5 EDO05644.1 - 0.0055 16.4 0.0 0.038 13.7 0.0 2.3 2 0 0 2 2 2 1 RAP domain PP2C PF00481.16 EDO05646.1 - 4e-43 147.6 0.0 4.9e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EDO05646.1 - 1.8e-05 24.2 0.0 5.1e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EDO05646.1 - 0.00051 19.7 0.0 0.12 12.0 0.0 2.4 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) ABC1 PF03109.11 EDO05647.1 - 3.8e-29 101.0 0.0 1.8e-28 98.9 0.0 2.0 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 EDO05647.1 - 0.0082 15.8 0.0 0.3 10.7 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF4325 PF14213.1 EDO05647.1 - 0.033 13.8 0.1 0.088 12.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4325) Ribosomal_L33 PF00471.15 EDO05648.1 - 4.7e-19 68.3 1.9 7.1e-19 67.7 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L33 ACBP PF00887.14 EDO05649.1 - 6.1e-30 102.7 1.1 6.6e-30 102.6 0.7 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Corona_NS2 PF04753.7 EDO05649.1 - 0.0027 17.6 0.1 0.0032 17.3 0.1 1.1 1 0 0 1 1 1 1 Coronavirus non-structural protein NS2 AP2 PF00847.15 EDO05650.1 - 5.4e-11 42.4 4.1 9.7e-11 41.6 2.9 1.4 1 0 0 1 1 1 1 AP2 domain JmjC PF02373.17 EDO05651.1 - 2.7e-35 121.0 0.1 5.8e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.11 EDO05651.1 - 3.4e-10 39.8 13.7 8.9e-10 38.4 9.5 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger JmjN PF02375.12 EDO05651.1 - 0.0017 17.8 0.0 0.0039 16.6 0.0 1.7 1 0 0 1 1 1 1 jmjN domain HEAT_EZ PF13513.1 EDO05652.1 - 9.2e-10 38.7 1.9 1.9e-05 25.0 0.0 4.3 3 1 0 3 3 3 2 HEAT-like repeat IBN_N PF03810.14 EDO05652.1 - 1.9e-08 34.1 0.0 1.2e-07 31.5 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.17 EDO05652.1 - 6.2e-07 28.9 0.1 0.018 15.0 0.0 5.0 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 EDO05652.1 - 8.5e-06 25.9 2.2 0.024 14.9 0.0 5.1 4 3 1 5 5 5 1 HEAT repeats Arm PF00514.18 EDO05652.1 - 0.0018 18.0 0.2 0.13 12.1 0.0 3.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat UME PF08064.8 EDO05652.1 - 0.012 15.5 1.1 5.2 7.0 0.0 4.4 4 1 1 5 5 5 0 UME (NUC010) domain DUF2164 PF09932.4 EDO05652.1 - 0.11 12.3 0.0 2.2 8.1 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2164) FTR_C PF02741.10 EDO05652.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 FTR, proximal lobe Pribosyltran PF00156.22 EDO05653.1 - 8.6e-17 61.0 0.1 1.3e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CPT PF07931.7 EDO05653.1 - 0.029 13.9 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RIIa PF02197.12 EDO05655.1 - 0.0097 15.3 0.5 0.038 13.4 0.0 2.3 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit DUF3467 PF11950.3 EDO05655.1 - 0.032 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) APG17 PF04108.7 EDO05655.1 - 0.13 11.0 2.1 0.44 9.3 0.7 1.9 2 0 0 2 2 2 0 Autophagy protein Apg17 OS-D PF03392.8 EDO05655.1 - 0.16 11.9 0.8 0.31 11.0 0.5 1.5 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D Nol1_Nop2_Fmu PF01189.12 EDO05656.1 - 1e-21 77.5 0.0 3e-20 72.7 0.0 2.8 2 1 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EDO05656.1 - 0.018 15.1 0.0 0.065 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 EDO05656.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase HECT PF00632.20 EDO05657.1 - 3.6e-70 236.6 0.0 6e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) LSM PF01423.17 EDO05658.1 - 0.0026 17.2 1.5 0.0088 15.5 0.0 2.4 3 0 0 3 3 3 1 LSM domain Trep_Strep PF09605.5 EDO05659.1 - 0.0027 17.4 0.4 0.15 11.6 0.0 2.1 2 0 0 2 2 2 2 Hypothetical bacterial integral membrane protein (Trep_Strep) B56 PF01603.15 EDO05661.1 - 5.2e-129 430.4 5.4 6.6e-129 430.1 3.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) V-SNARE PF05008.10 EDO05662.1 - 3.9e-05 23.7 2.7 6e-05 23.1 1.9 1.4 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus Allexi_40kDa PF05549.6 EDO05662.1 - 0.0016 17.7 4.1 0.002 17.4 2.9 1.0 1 0 0 1 1 1 1 Allexivirus 40kDa protein Gp37_Gp68 PF07505.6 EDO05662.1 - 0.0023 17.1 0.1 0.0026 16.9 0.1 1.0 1 0 0 1 1 1 1 Phage protein Gp37/Gp68 Muted PF14942.1 EDO05662.1 - 0.016 15.0 4.2 0.021 14.6 2.9 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF939_C PF11728.3 EDO05662.1 - 0.017 14.9 0.6 0.017 14.9 0.4 1.8 1 1 1 2 2 2 0 DUF939 C-terminal domain IL22 PF14565.1 EDO05662.1 - 0.025 14.6 0.3 0.048 13.7 0.1 1.5 1 1 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Seryl_tRNA_N PF02403.17 EDO05662.1 - 0.046 13.7 6.5 2 8.4 4.2 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF947 PF06102.7 EDO05662.1 - 0.072 12.9 0.9 0.1 12.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF947) BLOC1_2 PF10046.4 EDO05662.1 - 0.084 13.0 5.5 0.9 9.7 0.2 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TSC22 PF01166.13 EDO05662.1 - 0.09 12.7 2.5 1.4 8.8 0.5 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF2422 PF10337.4 EDO05662.1 - 0.097 11.4 0.1 0.34 9.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2422) Fib_alpha PF08702.5 EDO05662.1 - 0.14 12.2 4.5 0.65 10.1 3.1 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.8 EDO05662.1 - 0.16 11.0 4.0 0.18 10.8 2.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.4 EDO05662.1 - 0.17 10.8 4.5 0.19 10.6 3.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Frataxin_Cyay PF01491.11 EDO05662.1 - 0.17 11.6 1.3 1.4 8.6 0.7 2.2 1 1 0 1 1 1 0 Frataxin-like domain GTPase_Cys_C PF12631.2 EDO05662.1 - 0.24 11.8 2.2 4.6 7.7 0.8 2.3 2 1 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Ly49 PF08391.5 EDO05662.1 - 0.26 11.4 3.0 0.34 11.0 2.1 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF964 PF06133.6 EDO05662.1 - 0.38 10.7 4.2 0.39 10.7 2.2 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF964) Spc7 PF08317.6 EDO05662.1 - 0.42 9.2 4.9 0.52 8.9 3.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EDO05662.1 - 0.48 9.9 4.0 0.62 9.6 2.8 1.1 1 0 0 1 1 1 0 IncA protein DUF607 PF04678.8 EDO05662.1 - 0.55 10.1 2.0 0.6 10.0 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF607 VPS11_C PF12451.3 EDO05662.1 - 0.65 9.8 4.4 4 7.3 0.3 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Orthopox_A5L PF06193.6 EDO05662.1 - 0.81 9.6 4.5 1.7 8.5 3.1 1.6 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like APG6 PF04111.7 EDO05662.1 - 0.85 8.6 5.6 1.1 8.3 3.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 YlqD PF11068.3 EDO05662.1 - 0.85 9.6 4.0 0.64 10.0 1.9 1.4 2 0 0 2 2 1 0 YlqD protein DivIVA PF05103.8 EDO05662.1 - 0.95 9.5 7.9 2.2 8.3 5.5 1.6 1 1 0 1 1 1 0 DivIVA protein Fzo_mitofusin PF04799.8 EDO05662.1 - 1 8.7 5.1 10 5.4 2.8 2.0 1 1 1 2 2 2 0 fzo-like conserved region DUF3847 PF12958.2 EDO05662.1 - 1.3 8.8 4.7 10 5.9 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) FlaC_arch PF05377.6 EDO05662.1 - 1.5 8.7 3.7 10 6.0 0.1 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) CCDC-167 PF15188.1 EDO05662.1 - 2.1 8.3 6.2 5.2 7.0 4.0 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 RRM_1 PF00076.17 EDO05663.1 - 4.7e-16 58.1 0.0 1.7e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO05663.1 - 5.7e-11 42.2 0.0 4.6e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 EDO05663.1 - 5e-10 39.0 4.1 1.1e-09 37.9 2.8 1.6 1 0 0 1 1 1 1 WW domain RRM_5 PF13893.1 EDO05663.1 - 2.1e-07 30.6 0.0 8e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EDO05663.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain Suf PF05843.9 EDO05664.1 - 9.5e-07 28.8 8.3 0.13 11.9 0.4 5.6 5 1 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_12 PF13424.1 EDO05664.1 - 2.6e-05 24.0 7.1 0.45 10.4 0.0 6.2 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDO05664.1 - 5.1e-05 23.5 4.7 12 6.8 0.0 7.6 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDO05664.1 - 0.00089 18.8 1.9 0.32 10.6 0.0 4.6 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.1 EDO05664.1 - 0.0037 16.9 7.2 0.02 14.6 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EDO05664.1 - 0.033 13.9 0.5 0.033 13.9 0.3 5.9 4 2 1 6 6 6 0 Mad3/BUB1 homology region 1 TPR_2 PF07719.12 EDO05664.1 - 0.081 12.8 9.8 0.31 11.0 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDO05664.1 - 0.12 13.0 7.6 1.4 9.6 0.0 4.9 7 0 0 7 7 7 0 Tetratricopeptide repeat HAT PF02184.11 EDO05664.1 - 8.7 6.1 12.0 28 4.5 0.1 5.7 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat DUF1411 PF07199.6 EDO05665.1 - 7.2e-08 32.0 0.0 0.072 12.5 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1411) PRANC PF09372.5 EDO05666.1 - 0.0073 16.2 0.2 0.065 13.2 0.0 2.8 2 1 1 3 3 3 1 PRANC domain Lant_dehyd_C PF04738.8 EDO05666.1 - 0.013 13.7 0.2 0.23 9.6 0.1 2.4 2 0 0 2 2 2 0 Lantibiotic dehydratase, C terminus DUF2203 PF09969.4 EDO05666.1 - 0.092 12.9 0.1 2.2 8.5 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) NPV_P10 PF05531.7 EDO05666.1 - 0.76 10.0 5.9 8.4 6.7 0.3 3.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PNK3P PF08645.6 EDO05667.1 - 2.3e-41 140.8 0.0 3.5e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EDO05667.1 - 3.3e-14 52.9 0.0 1.3e-12 47.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 EDO05667.1 - 1.1e-05 24.8 0.8 0.0023 17.1 0.1 2.4 1 1 1 2 2 2 2 Chromatin associated protein KTI12 AAA_14 PF13173.1 EDO05667.1 - 0.0066 16.3 0.0 0.023 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EDO05667.1 - 0.011 14.8 0.0 0.5 9.4 0.0 2.6 2 1 1 3 3 3 0 Zeta toxin AAA_17 PF13207.1 EDO05667.1 - 0.026 15.3 0.4 0.4 11.4 0.2 2.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EDO05667.1 - 0.03 14.4 0.0 0.093 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EDO05667.1 - 0.043 14.0 0.0 0.094 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EDO05667.1 - 0.049 12.8 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 EDO05667.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ParcG PF10274.4 EDO05668.1 - 0.12 12.2 3.1 0.4 10.5 0.1 3.4 4 0 0 4 4 4 0 Parkin co-regulated protein COX2 PF00116.15 EDO05669.1 - 0.025 14.4 0.1 0.049 13.4 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, periplasmic domain Use1 PF09753.4 EDO05670.1 - 8.8e-05 22.0 4.0 0.00012 21.6 2.6 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 Muted PF14942.1 EDO05670.1 - 0.038 13.8 0.2 0.038 13.8 0.1 1.9 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein TFIIA PF03153.8 EDO05671.1 - 0.83 9.4 6.3 1.5 8.6 4.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec23_trunk PF04811.10 EDO05672.1 - 2.8e-40 138.2 0.0 4.5e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EDO05672.1 - 2.3e-22 79.3 0.1 5.9e-22 78.0 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EDO05672.1 - 7.1e-16 57.4 5.1 1.4e-15 56.5 3.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 EDO05672.1 - 4.9e-13 48.3 0.0 1.1e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 EDO05672.1 - 2.2e-07 30.4 0.0 4.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat VWA PF00092.23 EDO05672.1 - 0.0043 16.7 0.0 0.035 13.8 0.0 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RanBP PF00641.13 EDO05672.1 - 0.72 9.0 5.2 0.069 12.2 0.3 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PRMT5 PF05185.11 EDO05673.1 - 5.5e-145 483.6 0.4 6.8e-145 483.4 0.3 1.0 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 EDO05673.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DUF1411 PF07199.6 EDO05674.1 - 0.00018 20.9 0.2 0.36 10.2 0.0 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF1411) DUF1411 PF07199.6 EDO05675.1 - 6e-06 25.8 0.0 2.1e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1411) Glycolytic PF00274.14 EDO05677.1 - 1.8e-163 542.8 0.0 2.1e-163 542.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Prefoldin PF02996.12 EDO05678.1 - 2.8e-23 81.8 0.7 4.1e-23 81.3 0.5 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EDO05678.1 - 0.0033 17.1 2.4 0.077 12.7 0.1 2.3 2 0 0 2 2 2 1 Prefoldin subunit Fib_alpha PF08702.5 EDO05678.1 - 0.0044 17.1 5.8 0.28 11.2 0.7 2.1 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family IncA PF04156.9 EDO05678.1 - 0.0051 16.4 7.1 0.029 13.9 0.4 2.4 2 1 0 2 2 2 1 IncA protein SlyX PF04102.7 EDO05678.1 - 0.031 14.6 0.7 0.031 14.6 0.5 2.4 2 1 0 2 2 2 0 SlyX Laminin_II PF06009.7 EDO05678.1 - 0.043 13.5 2.1 0.39 10.4 0.1 2.1 2 0 0 2 2 2 0 Laminin Domain II Cep57_MT_bd PF06657.8 EDO05678.1 - 0.065 13.1 2.9 1.8 8.5 0.3 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Myc-LZ PF02344.10 EDO05678.1 - 0.071 12.7 1.3 0.16 11.6 0.1 2.1 2 0 0 2 2 2 0 Myc leucine zipper domain DUF4600 PF15372.1 EDO05678.1 - 0.081 13.1 3.6 2.1 8.5 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) COG5 PF10392.4 EDO05678.1 - 0.1 12.5 3.6 0.24 11.3 0.3 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF1192 PF06698.6 EDO05678.1 - 0.13 12.0 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF1664 PF07889.7 EDO05678.1 - 0.15 11.8 4.5 1.4 8.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Med10 PF09748.4 EDO05678.1 - 0.15 11.8 2.2 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex ING PF12998.2 EDO05678.1 - 0.21 11.8 3.6 0.8 10.0 2.5 2.0 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Tropomyosin_1 PF12718.2 EDO05678.1 - 0.31 10.8 4.4 2.7 7.8 0.4 2.3 2 1 0 2 2 2 0 Tropomyosin like DUF4200 PF13863.1 EDO05678.1 - 0.37 10.7 3.9 3.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Rootletin PF15035.1 EDO05678.1 - 0.55 10.1 6.5 1.2 9.0 0.7 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Spectrin PF00435.16 EDO05678.1 - 0.65 10.3 3.3 5.1 7.4 0.3 2.1 2 0 0 2 2 2 0 Spectrin repeat DUF869 PF05911.6 EDO05678.1 - 0.78 7.9 7.8 1.8 6.7 0.6 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) TMF_DNA_bd PF12329.3 EDO05678.1 - 3.1 7.6 7.5 0.98 9.2 0.3 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding OB_NTP_bind PF07717.11 EDO05679.1 - 1.1e-16 60.7 0.0 2.2e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EDO05679.1 - 1.5e-12 47.4 0.0 3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) CtaG_Cox11 PF04442.9 EDO05680.1 - 3.3e-52 176.3 0.1 4.5e-52 175.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Longin PF13774.1 EDO05681.1 - 0.00075 19.0 0.0 0.0018 17.7 0.0 1.7 2 0 0 2 2 2 1 Regulated-SNARE-like domain Shisa PF13908.1 EDO05681.1 - 0.048 13.8 0.2 0.068 13.3 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RWD PF05773.17 EDO05681.1 - 0.07 13.0 0.1 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain Chordopox_A33R PF05966.7 EDO05681.1 - 0.11 11.2 1.6 0.18 10.5 1.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein DUF4408 PF14364.1 EDO05681.1 - 5.6 6.6 7.3 11 5.7 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) MMS19_N PF14500.1 EDO05682.1 - 0.0018 17.5 1.2 0.35 10.0 0.1 2.3 2 0 0 2 2 2 2 Dos2-interacting transcription regulator of RNA-Pol-II Kin17_mid PF10357.4 EDO05683.1 - 2.6e-45 153.1 0.8 4.5e-45 152.3 0.6 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein KOW PF00467.24 EDO05683.1 - 0.0063 16.1 0.0 0.045 13.4 0.0 2.5 2 0 0 2 2 2 1 KOW motif zf-met PF12874.2 EDO05683.1 - 0.0065 16.6 3.3 0.02 15.1 2.3 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDO05683.1 - 0.02 15.0 5.1 0.046 13.8 3.6 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF3593 PF12159.3 EDO05683.1 - 0.055 13.2 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) zf-C2H2_2 PF12756.2 EDO05683.1 - 5.1 7.2 10.0 2.2 8.4 3.5 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Ribosomal_L22 PF00237.14 EDO05684.1 - 2.4e-06 27.4 0.0 5.8e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e WbqC PF08889.6 EDO05684.1 - 0.022 14.2 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 WbqC-like protein family Phage_RpbA PF10789.4 EDO05684.1 - 0.039 13.7 1.0 4 7.3 0.0 2.5 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA MgtE_N PF03448.12 EDO05684.1 - 0.041 14.2 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain TPR_8 PF13181.1 EDO05685.1 - 0.00071 19.1 0.0 0.41 10.5 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDO05685.1 - 0.0035 16.9 0.1 1.9 8.2 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.1 EDO05685.1 - 0.0099 16.4 0.0 47 5.0 0.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDO05685.1 - 0.01 16.1 1.5 7.6 6.9 0.1 3.7 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO05685.1 - 0.02 14.8 0.7 2 8.3 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO05685.1 - 0.065 12.8 0.3 6.8 6.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.15 EDO05685.1 - 0.15 11.6 5.6 2 7.9 0.1 3.5 3 1 0 3 3 3 0 Region in Clathrin and VPS RPN7 PF10602.4 EDO05685.1 - 0.3 10.4 4.5 9.1 5.6 0.0 3.5 2 1 0 3 3 3 0 26S proteasome subunit RPN7 RRM_1 PF00076.17 EDO05686.1 - 9e-06 25.2 0.0 0.0014 18.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.8 EDO05686.1 - 0.0017 18.8 0.0 0.0049 17.3 0.0 1.8 2 0 0 2 2 2 1 SPOC domain RRM_5 PF13893.1 EDO05686.1 - 0.0061 16.3 0.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO05686.1 - 0.038 13.9 0.0 4.8 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TPK_catalytic PF04263.11 EDO05688.1 - 0.04 13.4 0.1 0.042 13.4 0.1 1.3 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain Methyltransf_5 PF01795.14 EDO05689.1 - 8e-80 268.3 0.1 1.2e-78 264.5 0.0 2.0 1 1 0 1 1 1 1 MraW methylase family Methyltransf_18 PF12847.2 EDO05689.1 - 0.003 18.1 0.0 0.58 10.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EDO05689.1 - 0.0077 16.2 0.0 0.026 14.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Rotamase PF00639.16 EDO05690.1 - 1.9e-20 73.3 0.0 2.9e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EDO05690.1 - 2.6e-16 59.9 0.0 3.6e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EDO05690.1 - 1.2e-05 25.9 0.0 1.6e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain TAP42 PF04177.7 EDO05691.1 - 1.3e-42 145.9 4.3 2.5e-42 145.0 3.0 1.4 1 1 0 1 1 1 1 TAP42-like family Lactamase_B_2 PF12706.2 EDO05692.1 - 9.9e-20 70.9 0.0 2.1e-15 56.7 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EDO05692.1 - 9.2e-08 31.9 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Glycos_transf_4 PF00953.16 EDO05693.1 - 7.5e-33 113.5 14.3 1.5e-32 112.5 9.9 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 4 DUF3096 PF11295.3 EDO05693.1 - 0.4 10.2 6.5 0.3 10.6 0.9 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3096) AMP-binding PF00501.23 EDO05694.1 - 1.8e-79 267.0 0.0 2.4e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDO05694.1 - 0.0094 16.8 0.0 0.028 15.3 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain SMC_N PF02463.14 EDO05695.1 - 3.5e-11 42.7 0.0 3.9e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EDO05695.1 - 1.5e-10 41.7 0.0 1.7e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EDO05695.1 - 0.0082 16.1 0.0 0.0093 15.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EDO05695.1 - 0.015 14.4 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EDO05695.1 - 0.023 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.1 EDO05696.1 - 3.5e-05 22.4 77.2 4.6e-05 22.1 13.7 3.8 2 2 2 4 4 4 3 AAA domain SbcCD_C PF13558.1 EDO05696.1 - 0.00072 19.4 0.2 0.033 14.1 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Filament PF00038.16 EDO05696.1 - 0.0063 16.0 18.0 0.0063 16.0 12.5 5.4 2 2 2 4 4 4 2 Intermediate filament protein MscS_porin PF12795.2 EDO05696.1 - 0.024 13.9 53.7 0.011 15.0 2.3 5.2 2 2 2 4 4 4 0 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 EDO05696.1 - 0.031 13.4 25.9 1.6 7.8 0.1 5.3 2 2 4 6 6 6 0 Reovirus sigma C capsid protein DUF948 PF06103.6 EDO05696.1 - 0.051 13.4 0.3 0.051 13.4 0.2 6.0 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) WEMBL PF05701.6 EDO05696.1 - 0.065 11.6 67.0 0.0067 14.9 21.4 2.3 2 0 0 2 2 2 0 Weak chloroplast movement under blue light SMC_N PF02463.14 EDO05696.1 - 0.35 10.0 29.6 0.032 13.4 16.9 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Spc7 PF08317.6 EDO05696.1 - 3.6 6.1 81.7 0.0059 15.3 15.5 5.7 2 2 3 5 5 5 0 Spc7 kinetochore protein Wyosine_form PF08608.7 EDO05698.1 - 1.1e-24 86.3 0.1 2.8e-24 84.9 0.1 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 EDO05698.1 - 1.2e-20 74.2 0.0 2.7e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily DUF3861 PF12977.2 EDO05698.1 - 0.0057 16.7 0.1 0.038 14.0 0.0 2.4 2 1 1 3 3 3 1 Domain of Unknown Function with PDB structure (DUF3861) DUF4336 PF14234.1 EDO05698.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Hydrolase_6 PF13344.1 EDO05698.1 - 0.069 13.0 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RNA_pol_A_bac PF01000.21 EDO05699.1 - 9.1e-10 38.6 0.0 2.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EDO05699.1 - 0.00068 18.7 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF4079 PF13301.1 EDO05699.1 - 0.11 12.4 0.1 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF1411 PF07199.6 EDO05700.1 - 2.2e-09 37.0 0.1 1.3e-05 24.7 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1411) F-actin_cap_A PF01267.12 EDO05700.1 - 0.053 12.5 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 F-actin capping protein alpha subunit ThiF PF00899.16 EDO05702.1 - 3.5e-39 133.7 0.1 2.3e-38 131.0 0.1 2.1 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EDO05702.1 - 1e-22 79.4 0.6 1.9e-22 78.5 0.4 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EDO05702.1 - 1.3e-18 66.0 1.6 1.9e-18 65.5 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EDO05702.1 - 3.1e-08 33.5 0.0 1.5e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 EDO05702.1 - 0.0049 16.9 0.4 0.015 15.3 0.1 1.9 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EDO05702.1 - 0.013 15.7 0.1 0.042 14.1 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding ZZ PF00569.12 EDO05703.1 - 4.5e-06 26.0 10.6 1.2e-05 24.7 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EDO05703.1 - 4.7e-06 26.5 0.1 1.9e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Thioredoxin PF00085.15 EDO05704.1 - 2.7e-18 65.5 0.0 9.2e-18 63.8 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.1 EDO05704.1 - 8.6e-08 32.2 5.0 0.0011 18.7 1.4 3.7 2 1 3 5 5 5 2 Thioredoxin-like domain Glutaredoxin PF00462.19 EDO05704.1 - 3.5e-05 23.6 0.0 8.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.1 EDO05704.1 - 0.0017 18.3 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EDO05704.1 - 0.0028 17.8 0.1 0.014 15.5 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDO05704.1 - 0.079 13.0 0.1 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like Suf PF05843.9 EDO05705.1 - 3.6e-07 30.2 4.4 0.00028 20.7 0.0 3.7 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EDO05705.1 - 4.2e-05 23.7 0.1 0.081 13.5 0.0 4.5 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDO05705.1 - 0.0042 16.6 0.1 0.82 9.3 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 EDO05705.1 - 0.0049 17.5 0.0 0.064 13.9 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Flp_N PF03930.9 EDO05705.1 - 0.027 14.2 0.4 0.057 13.1 0.2 1.5 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus DUF760 PF05542.6 EDO05706.1 - 3.5e-42 142.4 0.7 2.6e-22 78.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF760) DUF1720 PF08226.6 EDO05706.1 - 0.01 15.8 2.8 0.03 14.3 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1720) ArfGap PF01412.13 EDO05709.1 - 1e-38 131.6 0.0 1.6e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Macro_2 PF14519.1 EDO05709.1 - 0.0089 15.1 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Macro-like domain IMCp PF12314.3 EDO05710.1 - 2.8e-21 75.4 52.9 8.7e-13 48.2 18.8 2.2 1 1 1 2 2 2 2 Inner membrane complex protein Sof1 PF04158.9 EDO05710.1 - 1.5 8.8 10.7 3.5 7.7 1.8 2.6 1 1 1 2 2 2 0 Sof1-like domain SpoU_methylase PF00588.14 EDO05711.1 - 1.5e-07 31.3 0.0 2.8e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family WD40 PF00400.27 EDO05712.1 - 3.5e-21 74.2 13.9 4.7e-06 26.2 0.2 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat WD40 PF00400.27 EDO05713.1 - 9.2e-17 60.2 4.7 6.1e-06 25.9 0.0 5.3 4 1 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EDO05713.1 - 6.7e-13 48.3 0.0 1.2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex tRNA-synt_His PF13393.1 EDO05716.1 - 1.9e-44 152.0 0.0 2.9e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EDO05716.1 - 1.5e-15 57.2 0.0 2.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDO05716.1 - 3.3e-08 33.3 0.0 1.1e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EDO05716.1 - 0.00055 18.8 2.6 0.016 14.0 0.0 3.1 3 1 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EDO05716.1 - 0.0034 16.6 0.0 0.0067 15.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) DEAD PF00270.24 EDO05717.1 - 4.2e-34 117.4 0.3 7.8e-34 116.5 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO05717.1 - 3.3e-17 62.1 2.1 1.3e-16 60.2 0.5 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDO05717.1 - 9.8e-06 24.5 0.7 1.5e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 EDO05717.1 - 0.0054 16.5 0.7 0.016 15.0 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDO05717.1 - 0.0056 16.8 2.9 0.068 13.3 0.5 3.1 2 2 0 2 2 2 1 AAA domain OmdA PF13376.1 EDO05717.1 - 0.051 13.2 0.3 0.2 11.3 0.2 2.0 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated YfhD PF14151.1 EDO05717.1 - 3.8 7.7 10.4 0.21 11.7 2.8 2.1 2 0 0 2 2 2 0 YfhD-like protein FSH1 PF03959.8 EDO05718.1 - 2.9e-31 108.5 0.0 4.1e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EDO05718.1 - 0.00028 20.6 0.0 0.001 18.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO05718.1 - 0.001 18.9 0.0 0.064 13.1 0.0 2.7 2 1 1 3 3 3 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EDO05718.1 - 0.0011 18.6 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DLH PF01738.13 EDO05718.1 - 0.0016 17.7 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF2048 PF09752.4 EDO05718.1 - 0.087 11.6 0.0 8.6 5.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_3 PF07859.8 EDO05718.1 - 0.13 11.8 0.0 0.38 10.3 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold DAP3 PF10236.4 EDO05719.1 - 1.4e-26 93.1 0.1 1.5e-15 56.9 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.1 EDO05719.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EDO05719.1 - 0.024 14.7 0.1 0.14 12.2 0.0 2.2 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EDO05719.1 - 0.035 13.7 0.2 0.59 9.7 0.1 2.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 EDO05719.1 - 0.056 13.4 0.1 0.32 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.20 EDO05720.1 - 4.1e-49 167.0 0.0 5.2e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO05720.1 - 2.1e-21 76.1 0.1 3.8e-21 75.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EDO05720.1 - 0.015 15.0 0.0 3.4 7.3 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EDO05720.1 - 0.025 13.9 1.3 0.12 11.7 0.0 2.4 2 0 0 2 2 2 0 RIO1 family HAP1_N PF04849.8 EDO05721.1 - 0.041 12.8 1.0 0.063 12.2 0.7 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Peptidase_M16 PF00675.15 EDO05723.1 - 2.8e-46 156.9 0.0 5.7e-46 155.9 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDO05723.1 - 2e-32 112.3 0.0 5.2e-32 111.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Spc97_Spc98 PF04130.8 EDO05724.1 - 5.1e-30 104.3 5.3 6.3e-26 90.8 0.2 2.3 1 1 1 2 2 2 2 Spc97 / Spc98 family TPR_MLP1_2 PF07926.7 EDO05725.1 - 0.00012 21.8 21.8 0.051 13.3 1.7 4.2 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EDO05725.1 - 0.043 13.6 35.1 0.026 14.3 4.2 4.9 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EDO05725.1 - 0.044 13.3 29.4 0.27 10.8 7.4 2.7 2 0 0 2 2 2 0 IncA protein DUF3166 PF11365.3 EDO05725.1 - 3 8.3 16.5 0.54 10.7 0.3 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF3166) Prefoldin_2 PF01920.15 EDO05725.1 - 4.4 7.1 21.5 0.16 11.7 1.6 4.4 2 2 2 5 5 5 0 Prefoldin subunit DUF1227 PF06777.6 EDO05727.1 - 1.2e-50 170.9 0.0 2.5e-50 169.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 EDO05727.1 - 9.6e-43 146.0 0.0 4.9e-42 143.7 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EDO05727.1 - 4e-21 75.1 0.7 9.1e-12 44.7 0.0 3.1 2 1 0 2 2 2 2 DEAD_2 ResIII PF04851.10 EDO05727.1 - 1e-07 31.9 0.0 0.00033 20.5 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.24 EDO05727.1 - 0.001 18.6 0.2 0.042 13.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase CytadhesinP1 PF12378.3 EDO05727.1 - 0.062 13.2 0.1 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Trypsin-sensitive surface-exposed protein UBX PF00789.15 EDO05728.1 - 2.8e-13 49.7 0.0 6e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain MORN PF02493.15 EDO05729.1 - 9.5e-81 260.9 95.4 7e-08 31.7 2.9 14.2 14 0 0 14 14 14 14 MORN repeat Mpp10 PF04006.7 EDO05730.1 - 5.4e-18 64.7 74.5 2.2e-16 59.3 51.7 3.0 1 1 0 1 1 1 1 Mpp10 protein tRNA-synt_2b PF00587.20 EDO05731.1 - 3.3e-33 114.7 0.0 6.9e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EDO05731.1 - 1.2e-06 28.4 0.5 2.6e-06 27.4 0.3 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Syntaxin_2 PF14523.1 EDO05731.1 - 0.007 16.3 1.1 0.022 14.8 0.7 1.9 1 0 0 1 1 1 1 Syntaxin-like protein Img2 PF05046.9 EDO05731.1 - 0.0078 16.4 0.7 0.7 10.1 0.1 3.4 3 0 0 3 3 3 1 Mitochondrial large subunit ribosomal protein (Img2) Atg14 PF10186.4 EDO05731.1 - 0.016 14.1 0.5 0.058 12.3 0.3 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LXG PF04740.7 EDO05731.1 - 0.035 13.9 0.8 0.068 12.9 0.6 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily FliD_C PF07195.7 EDO05731.1 - 0.045 13.0 0.7 0.089 12.0 0.5 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus TBPIP PF07106.8 EDO05731.1 - 0.16 11.4 1.4 0.38 10.2 1.0 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EDO05731.1 - 0.21 11.1 1.9 0.42 10.1 1.3 1.4 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EDO05731.1 - 0.21 11.0 2.1 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator SRP19 PF01922.12 EDO05733.1 - 2.2e-27 95.4 0.1 3e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 SRP19 protein MACPF PF01823.14 EDO05734.1 - 1.4e-42 145.7 1.6 3.5e-42 144.5 1.1 1.7 1 0 0 1 1 1 1 MAC/Perforin domain CDC45 PF02724.9 EDO05734.1 - 0.39 8.7 39.5 0.094 10.7 11.3 2.1 1 1 0 2 2 2 0 CDC45-like protein Gemini_mov PF01708.11 EDO05735.1 - 3.2 7.3 11.6 6.5 6.3 1.0 2.8 2 0 0 2 2 2 0 Geminivirus putative movement protein ProRS-C_1 PF09180.6 EDO05736.1 - 1.8e-24 85.4 0.3 3.9e-23 81.1 0.0 2.8 3 0 0 3 3 3 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.10 EDO05736.1 - 3.1e-23 81.9 0.0 5.4e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.20 EDO05736.1 - 3.4e-21 75.6 0.6 7.2e-21 74.5 0.2 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDO05736.1 - 1.7e-17 63.0 0.1 7.9e-17 60.9 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain Hexapep PF00132.19 EDO05737.1 - 1.7e-05 24.0 12.3 0.015 14.7 1.0 2.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EDO05737.1 - 0.011 15.1 0.1 0.047 12.9 0.0 2.1 2 0 0 2 2 2 0 Nucleotidyl transferase UvrD_C PF13361.1 EDO05737.1 - 0.027 13.9 0.3 0.062 12.7 0.1 1.6 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Fucokinase PF07959.7 EDO05737.1 - 0.063 11.8 2.0 0.16 10.4 0.5 2.1 2 0 0 2 2 2 0 L-fucokinase Sec23_helical PF04815.10 EDO05738.1 - 0.065 12.6 0.3 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Sec23/Sec24 helical domain CHCH PF06747.8 EDO05738.1 - 2.9 7.9 5.7 18 5.3 0.5 2.5 2 0 0 2 2 2 0 CHCH domain Phosphodiest PF01663.17 EDO05739.1 - 3.4e-05 23.3 0.1 6.5e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EDO05739.1 - 0.0028 17.0 0.1 0.0048 16.3 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily zf-RNPHF PF08080.7 EDO05740.1 - 0.1 12.1 0.2 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 RNPHF zinc finger VKOR PF07884.9 EDO05740.1 - 0.63 9.8 6.9 3.3 7.5 1.7 2.8 3 0 0 3 3 3 0 Vitamin K epoxide reductase family Prenyltrans PF00432.16 EDO05741.1 - 6.8e-17 60.7 1.8 0.0011 18.4 0.0 5.0 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDO05741.1 - 1.3e-11 44.8 0.0 3.3e-08 33.9 0.0 3.5 3 1 1 4 4 4 3 Prenyltransferase-like Fer2 PF00111.22 EDO05743.1 - 1.3e-05 24.8 4.2 7.8e-05 22.3 2.9 2.0 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1364 PF07102.7 EDO05743.1 - 0.051 13.4 0.1 0.082 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Tim17 PF02466.14 EDO05745.1 - 0.066 13.2 0.8 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Polysacc_synt_C PF14667.1 EDO05745.1 - 0.14 11.9 19.8 0.039 13.7 2.2 3.0 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain DUF4383 PF14325.1 EDO05745.1 - 0.51 10.3 6.9 0.16 11.9 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4383) TauE PF01925.14 EDO05745.1 - 0.73 9.2 20.2 0.34 10.3 11.1 2.1 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE DUF1673 PF07895.6 EDO05745.1 - 3.3 7.1 13.1 7.7 5.9 9.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) VESA1_N PF12785.2 EDO05746.1 - 1.1e-28 100.4 5.1 1.8e-27 96.4 0.7 3.8 3 1 1 4 4 4 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05747.1 - 1.4e-215 716.6 23.7 1.4e-215 716.6 16.4 2.4 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 DDE_Tnp_1_assoc PF13808.1 EDO05747.1 - 0.094 12.3 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-associated RBP_receptor PF14752.1 EDO05748.1 - 0.0013 17.2 0.1 0.0014 17.0 0.1 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor DUF2956 PF11169.3 EDO05748.1 - 0.015 15.2 0.1 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) TAFH PF07531.9 EDO05748.1 - 0.062 12.9 0.4 0.09 12.4 0.3 1.2 1 0 0 1 1 1 0 NHR1 homology to TAF DNA_ligase_A_M PF01068.16 EDO05749.1 - 3.2e-59 199.6 0.1 6e-59 198.8 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EDO05749.1 - 9.3e-42 142.8 0.2 2.7e-41 141.3 0.1 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EDO05749.1 - 6.5e-27 93.7 0.0 1.5e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region PUB PF09409.5 EDO05750.1 - 1.5e-13 50.3 0.0 2.9e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 PUB domain Acyltransferase PF01553.16 EDO05751.1 - 1.7e-14 53.3 0.0 3.2e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF3894 PF13033.1 EDO05751.1 - 2.1 8.3 5.5 2.8 8.0 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3894) SET PF00856.23 EDO05752.1 - 1.2e-12 48.3 2.6 4.6e-11 43.2 0.1 3.0 2 1 2 4 4 4 1 SET domain SAF PF08666.7 EDO05752.1 - 0.17 12.2 0.0 29 5.1 0.0 3.1 3 0 0 3 3 3 0 SAF domain PGC7_Stella PF15549.1 EDO05753.1 - 0.065 13.2 0.1 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain PSD2 PF07624.6 EDO05755.1 - 0.11 12.2 0.0 1.4 8.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1585) FGF-BP1 PF06473.7 EDO05756.1 - 0.041 13.4 0.1 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) G6PD_C PF02781.11 EDO05757.1 - 1.7e-52 178.0 0.0 2.7e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Glucosamine_iso PF01182.15 EDO05757.1 - 2.5e-39 135.0 0.0 3.7e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase G6PD_N PF00479.17 EDO05757.1 - 4.5e-39 134.5 0.0 8.4e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF4134 PF13572.1 EDO05758.1 - 0.098 12.7 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) VMA21 PF09446.5 EDO05758.1 - 0.21 11.5 1.8 0.26 11.2 1.2 1.2 1 0 0 1 1 1 0 VMA21-like domain DUF410 PF04190.8 EDO05759.1 - 2.6e-06 27.1 0.0 1.7e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF410) DUF4479 PF14794.1 EDO05759.1 - 0.015 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) SNAP PF14938.1 EDO05759.1 - 0.051 12.7 0.0 0.1 11.7 0.0 1.4 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 EDO05759.1 - 0.11 12.8 1.5 0.69 10.2 0.3 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat CPSF73-100_C PF11718.3 EDO05760.1 - 3.5e-34 118.0 0.2 5.6e-34 117.3 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EDO05760.1 - 1e-30 106.2 0.0 2.3e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EDO05760.1 - 2.2e-16 60.0 0.2 5.7e-16 58.7 0.1 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EDO05760.1 - 1e-11 44.4 0.0 2e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EDO05760.1 - 1.6e-11 44.1 0.5 9.2e-11 41.6 0.1 2.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EDO05760.1 - 0.00047 19.8 0.0 0.0034 17.1 0.0 2.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain MMR_HSR1_C PF08438.5 EDO05761.1 - 3e-30 104.6 0.0 6.6e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EDO05761.1 - 4.4e-16 58.8 0.0 1.1e-15 57.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EDO05761.1 - 0.00058 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EDO05761.1 - 0.0016 17.7 0.1 0.0063 15.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Tox-REase-7 PF15649.1 EDO05761.1 - 0.027 14.5 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 7 AAA_33 PF13671.1 EDO05761.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain HSP20 PF00011.16 EDO05762.1 - 7.7e-13 48.1 0.1 1.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Lung_7-TM_R PF06814.8 EDO05763.1 - 1.8e-07 30.3 10.2 2.8e-07 29.7 7.1 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 EDO05763.1 - 0.00031 20.0 6.3 0.00069 18.8 4.4 1.7 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Ribosomal_L34e PF01199.13 EDO05765.1 - 3.4e-38 129.7 9.6 3.4e-38 129.7 6.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L34e Hc1 PF07432.8 EDO05765.1 - 0.0057 16.8 17.2 0.0092 16.1 11.9 1.3 1 0 0 1 1 1 1 Histone H1-like protein Hc1 Calreticulin PF00262.13 EDO05765.1 - 0.03 12.9 0.1 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 Calreticulin family DUF2461 PF09365.5 EDO05765.1 - 0.05 13.0 0.6 0.067 12.5 0.4 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) DUF1428 PF07237.6 EDO05765.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1428) DUF4549 PF15082.1 EDO05765.1 - 0.089 12.4 0.7 0.13 11.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) Pox_A3L PF05288.6 EDO05765.1 - 0.24 11.1 1.7 0.36 10.6 0.1 1.9 2 0 0 2 2 2 0 Poxvirus A3L Protein tRNA-synt_2 PF00152.15 EDO05766.1 - 5.6e-67 225.9 0.2 7.8e-67 225.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDO05766.1 - 4.1e-09 36.1 0.1 8.3e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain AAA PF00004.24 EDO05767.1 - 2e-93 309.5 0.0 2.9e-45 153.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDO05767.1 - 1.6e-14 53.5 0.0 7.2e-06 25.2 0.0 3.2 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EDO05767.1 - 2.7e-14 54.0 0.2 1.7e-06 28.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDO05767.1 - 1.6e-12 47.8 0.2 6.7e-05 22.9 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EDO05767.1 - 2.1e-12 47.3 0.7 0.00051 20.1 0.2 4.3 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EDO05767.1 - 2.4e-12 46.7 0.1 1.2e-05 25.0 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDO05767.1 - 4.6e-12 46.1 0.0 1e-05 25.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EDO05767.1 - 2.4e-11 43.0 0.1 1e-05 24.7 0.0 2.7 3 0 0 3 3 3 2 Zeta toxin AAA_14 PF13173.1 EDO05767.1 - 4.2e-11 42.8 0.0 0.00016 21.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EDO05767.1 - 1.1e-10 41.5 0.0 3.2e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EDO05767.1 - 4.4e-10 38.8 1.7 5.9e-05 21.9 0.0 2.6 3 0 0 3 3 3 2 TIP49 C-terminus AAA_19 PF13245.1 EDO05767.1 - 2e-09 37.0 1.3 0.00049 19.8 0.4 3.1 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 EDO05767.1 - 7e-09 35.3 0.1 0.0042 16.5 0.1 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EDO05767.1 - 7.8e-08 32.6 0.1 0.004 17.4 0.1 2.9 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EDO05767.1 - 1.8e-07 31.3 0.0 0.013 15.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EDO05767.1 - 1.8e-07 31.2 0.0 0.0053 16.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EDO05767.1 - 4.7e-07 29.6 0.3 0.24 11.0 0.0 3.9 3 1 1 4 4 4 2 NACHT domain Mg_chelatase PF01078.16 EDO05767.1 - 8e-07 28.4 0.3 0.016 14.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 EDO05767.1 - 1e-06 28.4 0.0 0.0034 16.9 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.1 EDO05767.1 - 2.6e-06 27.5 0.0 0.1 12.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EDO05767.1 - 4.8e-06 25.6 0.1 0.028 13.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 EDO05767.1 - 7.1e-06 25.8 0.0 0.16 11.5 0.0 3.2 3 0 0 3 3 3 2 Bacterial dnaA protein AAA_25 PF13481.1 EDO05767.1 - 8.1e-06 25.3 1.4 0.27 10.6 0.0 3.8 2 2 1 3 3 3 2 AAA domain Vps4_C PF09336.5 EDO05767.1 - 1.5e-05 24.7 0.0 6.2e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.21 EDO05767.1 - 1.7e-05 24.3 0.1 0.23 10.9 0.0 3.5 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EDO05767.1 - 1.9e-05 24.9 0.0 0.22 11.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter KaiC PF06745.8 EDO05767.1 - 3.7e-05 22.9 0.0 0.037 13.1 0.0 2.8 2 1 0 2 2 2 1 KaiC Arch_ATPase PF01637.13 EDO05767.1 - 4.5e-05 23.2 0.2 0.9 9.1 0.1 3.5 2 2 1 3 3 3 2 Archaeal ATPase NTPase_1 PF03266.10 EDO05767.1 - 5.1e-05 23.0 0.6 4.3 7.0 0.0 4.2 3 1 1 4 4 4 0 NTPase CDC48_N PF02359.13 EDO05767.1 - 6.7e-05 22.7 0.2 0.00026 20.8 0.3 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_3 PF07726.6 EDO05767.1 - 7.6e-05 22.3 0.0 0.26 10.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EDO05767.1 - 9.4e-05 21.7 0.0 0.25 10.5 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.17 EDO05767.1 - 0.00045 19.1 0.0 0.29 9.9 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain DUF2075 PF09848.4 EDO05767.1 - 0.00048 19.2 0.0 0.14 11.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EDO05767.1 - 0.00059 19.7 0.0 0.3 10.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.8 EDO05767.1 - 0.00064 18.7 0.0 0.44 9.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 EDO05767.1 - 0.00094 18.8 0.1 0.23 11.0 0.0 2.5 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 EDO05767.1 - 0.0023 17.5 0.1 1.8 8.2 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EDO05767.1 - 0.0029 17.2 0.2 0.36 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EDO05767.1 - 0.0032 17.0 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Cytidylate_kin2 PF13189.1 EDO05767.1 - 0.0051 16.7 2.0 0.24 11.3 0.0 2.7 3 0 0 3 3 2 1 Cytidylate kinase-like family AAA_30 PF13604.1 EDO05767.1 - 0.0072 15.9 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 EDO05767.1 - 0.02 14.7 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase T2SE PF00437.15 EDO05767.1 - 0.022 13.6 0.0 3.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 EDO05767.1 - 0.023 15.0 2.7 4.8 7.4 0.0 3.2 3 1 1 4 4 3 0 AAA domain DAP3 PF10236.4 EDO05767.1 - 0.027 13.4 0.0 3.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 KTI12 PF08433.5 EDO05767.1 - 0.058 12.5 0.1 6 5.9 0.0 2.7 3 0 0 3 3 2 0 Chromatin associated protein KTI12 KAP_NTPase PF07693.9 EDO05767.1 - 0.059 12.3 0.0 3.6 6.4 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain cobW PF02492.14 EDO05767.1 - 0.078 12.4 0.1 7.6 5.9 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Torsin PF06309.6 EDO05767.1 - 0.099 12.5 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Torsin Molydop_binding PF01568.16 EDO05767.1 - 0.2 11.5 0.0 0.92 9.3 0.0 2.0 2 0 0 2 2 1 0 Molydopterin dinucleotide binding domain DNA_mis_repair PF01119.14 EDO05768.1 - 5.7e-26 90.3 0.1 1.3e-25 89.2 0.1 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EDO05768.1 - 4e-14 52.4 0.0 2.6e-13 49.7 0.0 2.3 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EDO05768.1 - 4.6e-09 36.0 0.3 1.5e-08 34.3 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDO05768.1 - 1.4e-07 31.2 0.1 4.1e-07 29.6 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UCH PF00443.24 EDO05770.1 - 3e-47 160.9 0.8 4.5e-47 160.4 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO05770.1 - 5.8e-19 68.6 0.1 2.4e-11 43.6 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EDO05770.1 - 1.7e-09 37.4 0.1 5.7e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal DUF211 PF02680.9 EDO05770.1 - 0.14 11.9 0.1 0.36 10.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 CSTF_C PF14304.1 EDO05771.1 - 0.047 12.9 0.1 0.1 11.8 0.1 1.5 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal RNA_pol_3_Rpc31 PF11705.3 EDO05771.1 - 0.062 13.2 4.5 0.072 13.0 1.7 1.7 1 1 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2185 PF09951.4 EDO05771.1 - 0.089 12.5 2.9 0.13 12.0 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) Fzo_mitofusin PF04799.8 EDO05772.1 - 0.12 11.7 0.9 0.18 11.1 0.6 1.3 1 0 0 1 1 1 0 fzo-like conserved region Lzipper-MIP1 PF14389.1 EDO05772.1 - 0.3 11.2 3.2 2.8 8.0 0.8 2.7 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 CCDC-167 PF15188.1 EDO05772.1 - 0.57 10.1 6.2 0.92 9.4 3.1 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 EPSP_synthase PF00275.15 EDO05773.1 - 0.042 12.2 0.3 0.065 11.6 0.2 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Nol1_Nop2_Fmu PF01189.12 EDO05774.1 - 6.7e-15 55.2 0.0 1.3e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EDO05774.1 - 0.00028 20.5 0.0 0.00061 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO05774.1 - 0.00091 19.7 0.0 0.0023 18.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO05774.1 - 0.0019 18.2 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EDO05774.1 - 0.024 14.6 0.0 0.06 13.3 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EDO05774.1 - 0.03 14.6 0.0 0.069 13.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 EDO05774.1 - 0.074 12.0 0.0 1.5 7.8 0.0 2.2 1 1 0 2 2 2 0 O-methyltransferase YhfH PF14149.1 EDO05774.1 - 1.2 8.9 4.6 0.49 10.2 0.7 2.1 2 0 0 2 2 2 0 YhfH-like protein Vps51 PF08700.6 EDO05775.1 - 1.3e-11 44.1 1.0 2.3e-10 40.1 0.1 2.8 2 0 0 2 2 2 1 Vps51/Vps67 Hist_deacetyl PF00850.14 EDO05777.1 - 6.4e-69 232.6 0.0 1.7e-68 231.2 0.0 1.7 1 0 0 1 1 1 1 Histone deacetylase domain Ank_4 PF13637.1 EDO05777.1 - 6.3e-11 42.4 0.6 2.5e-05 24.6 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDO05777.1 - 8e-10 38.6 0.1 0.001 19.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDO05777.1 - 1.5e-07 31.6 0.0 0.0018 18.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EDO05777.1 - 1.4e-05 24.8 0.2 0.13 12.5 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 EDO05777.1 - 0.0027 17.4 3.1 3.9 7.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ssl1 PF04056.9 EDO05778.1 - 1e-50 171.9 0.0 1.5e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 EDO05778.1 - 6.1e-12 45.9 0.0 9e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EDO05778.1 - 1.3e-05 25.0 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EDO05778.1 - 0.0011 18.3 0.6 0.0017 17.6 0.4 1.3 1 0 0 1 1 1 1 Transcription factor Tfb4 Clathrin PF00637.15 EDO05779.1 - 2.6e-146 480.9 19.2 1.4e-29 102.4 0.3 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EDO05779.1 - 2.7e-22 78.4 0.1 4e-21 74.6 0.0 2.9 2 0 0 2 2 2 1 Clathrin-H-link Coatomer_WDAD PF04053.9 EDO05779.1 - 1.3e-06 27.5 1.8 0.1 11.3 0.0 3.6 3 0 0 3 3 3 3 Coatomer WD associated region Clathrin_propel PF01394.15 EDO05779.1 - 2.4e-05 24.3 0.9 1.1 9.6 0.0 4.0 3 0 0 3 3 3 2 Clathrin propeller repeat TPR_1 PF00515.23 EDO05779.1 - 3.7e-05 23.1 6.1 0.096 12.3 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDO05779.1 - 0.0013 19.2 8.1 83 4.2 0.0 8.3 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDO05779.1 - 0.0013 18.4 11.0 0.046 13.6 0.0 5.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO05779.1 - 0.0056 16.3 1.6 32 4.6 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDO05779.1 - 0.013 15.2 11.6 10 6.2 0.0 6.9 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDO05779.1 - 0.028 15.0 9.8 0.25 12.0 0.5 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EDO05779.1 - 0.49 10.0 0.0 0.49 10.0 0.0 4.8 6 0 0 6 6 5 0 TPR repeat E1-E2_ATPase PF00122.15 EDO05780.1 - 3.2e-14 52.5 1.2 1.4e-13 50.4 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EDO05780.1 - 1.5e-11 44.8 0.2 4.5e-11 43.2 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO05780.1 - 4.3e-11 43.6 0.1 1.1e-06 29.1 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDO05780.1 - 0.0096 15.5 0.1 0.036 13.6 0.0 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GATase_4 PF13230.1 EDO05780.1 - 0.013 14.2 0.2 0.044 12.4 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferases class-II DEAD PF00270.24 EDO05781.1 - 1.7e-48 164.2 0.0 5.1e-48 162.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO05781.1 - 1.1e-27 95.6 0.1 2.7e-26 91.2 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EDO05781.1 - 0.00018 20.0 0.1 0.00093 17.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) Med6 PF04934.9 EDO05783.1 - 7.7e-27 93.5 0.0 1.2e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component HECT_2 PF09814.4 EDO05784.1 - 0.00024 19.9 0.4 0.0047 15.7 0.0 2.6 3 0 0 3 3 3 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DZR PF12773.2 EDO05784.1 - 1.2 9.0 4.0 29 4.5 3.2 2.6 1 1 1 2 2 2 0 Double zinc ribbon Sua5_yciO_yrdC PF01300.13 EDO05785.1 - 6.6e-39 132.9 0.0 1.1e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EDO05785.1 - 7.7e-14 51.8 0.0 1.3e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding AAA PF00004.24 EDO05787.1 - 4.8e-15 55.9 0.2 3.6e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO05787.1 - 2.5e-09 37.3 0.0 7.5e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO05787.1 - 6e-08 32.8 0.0 1e-06 28.8 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EDO05787.1 - 1.2e-06 27.7 0.0 2.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EDO05787.1 - 6e-06 26.1 2.4 5e-05 23.1 1.7 2.3 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EDO05787.1 - 3e-05 23.7 0.0 5.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EDO05787.1 - 0.00089 19.4 2.2 0.21 11.7 0.3 3.0 2 1 0 2 2 2 1 RNA helicase AAA_17 PF13207.1 EDO05787.1 - 0.0012 19.7 0.0 0.0039 17.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain ORC4_C PF14629.1 EDO05787.1 - 0.003 16.9 0.1 0.0056 16.0 0.1 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_19 PF13245.1 EDO05787.1 - 0.01 15.5 0.2 0.029 14.1 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_11 PF13086.1 EDO05787.1 - 0.011 15.3 0.1 0.032 13.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EDO05787.1 - 0.023 14.6 0.1 0.054 13.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EDO05787.1 - 0.034 13.7 0.1 0.77 9.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EDO05787.1 - 0.042 12.8 0.0 0.083 11.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KAP_NTPase PF07693.9 EDO05787.1 - 0.05 12.5 0.5 0.49 9.3 0.1 2.2 1 1 1 2 2 2 0 KAP family P-loop domain ArgK PF03308.11 EDO05787.1 - 0.058 12.1 0.2 0.1 11.3 0.2 1.3 1 0 0 1 1 1 0 ArgK protein UPF0079 PF02367.12 EDO05787.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EDO05787.1 - 0.081 11.8 0.2 0.16 10.8 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein HMG_box PF00505.14 EDO05788.1 - 2.1e-25 88.7 2.2 2.8e-25 88.3 1.5 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDO05788.1 - 2.1e-15 56.8 2.3 2.7e-15 56.4 1.6 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EDO05788.1 - 0.0029 17.3 2.9 0.0051 16.5 2.0 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box 5 YABBY PF04690.8 EDO05788.1 - 0.014 15.6 1.5 0.015 15.5 0.8 1.3 1 1 0 1 1 1 0 YABBY protein DUF2582 PF10771.4 EDO05788.1 - 0.04 13.7 0.1 0.086 12.7 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2582) DUF4355 PF14265.1 EDO05788.1 - 0.43 10.5 3.7 0.59 10.0 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) AATF-Che1 PF13339.1 EDO05789.1 - 7.4e-06 26.1 4.1 8.7e-06 25.9 1.2 2.2 1 1 1 2 2 2 1 Apoptosis antagonizing transcription factor DNA_gyraseB PF00204.20 EDO05789.1 - 3.9 6.6 6.6 1.4 8.1 0.1 2.6 3 0 0 3 3 3 0 DNA gyrase B FbpA PF05833.6 EDO05790.1 - 9.1e-32 110.1 0.2 9.7e-22 77.1 0.0 2.2 2 0 0 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EDO05790.1 - 6.7e-24 83.5 0.0 1.2e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DUF3441 PF11923.3 EDO05790.1 - 9.7e-22 76.6 0.0 2.2e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) Rav1p_C PF12234.3 EDO05791.1 - 3.3e-20 71.8 0.0 2.3e-19 69.0 0.0 2.1 2 0 0 2 2 2 1 RAVE protein 1 C terminal YqgF PF14639.1 EDO05791.1 - 0.11 12.1 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Peptidase_M24 PF00557.19 EDO05792.1 - 1.2e-42 145.8 0.7 3.9e-23 82.1 0.1 2.2 2 0 0 2 2 2 2 Metallopeptidase family M24 FHA PF00498.21 EDO05793.1 - 1.6e-20 72.9 0.8 7.9e-10 38.7 0.7 2.7 2 0 0 2 2 2 2 FHA domain zf-C3HC4_4 PF15227.1 EDO05793.1 - 1.2e-08 34.6 11.0 3.9e-08 33.0 7.6 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EDO05793.1 - 1.7e-07 30.7 8.4 5.6e-07 29.1 5.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO05793.1 - 6.7e-07 28.8 4.8 6.7e-07 28.8 3.3 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO05793.1 - 7.4e-07 28.9 11.0 7.4e-07 28.9 7.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDO05793.1 - 6.3e-06 26.1 10.6 6.3e-06 26.1 7.4 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO05793.1 - 0.00024 20.7 5.5 0.00083 19.0 3.8 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EDO05793.1 - 0.0028 17.3 9.7 0.0092 15.6 6.7 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EDO05793.1 - 1.2 9.2 6.6 5 7.3 4.6 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger CactinC_cactus PF09732.4 EDO05797.1 - 1.4e-42 144.1 0.2 2.7e-42 143.2 0.1 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 EDO05797.1 - 4.4e-25 88.0 0.5 4.3e-24 84.8 0.3 2.1 1 1 0 1 1 1 1 Conserved mid region of cactin TPR_11 PF13414.1 EDO05798.1 - 1.3e-15 56.8 0.9 1.3e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 TPR repeat SHNi-TPR PF10516.4 EDO05798.1 - 4e-15 54.7 0.0 1e-13 50.2 0.0 2.4 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.1 EDO05798.1 - 4.7e-13 48.8 0.3 1.5e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO05798.1 - 9.8e-09 34.4 0.1 0.01 15.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO05798.1 - 1.4e-08 33.9 0.1 0.03 13.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO05798.1 - 4.1e-06 26.1 0.1 0.37 10.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 EDO05798.1 - 2.4e-05 23.6 5.9 8.9e-05 21.7 2.7 2.6 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 EDO05798.1 - 0.00039 20.0 0.0 0.054 13.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EDO05798.1 - 0.033 14.1 0.0 0.97 9.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDO05798.1 - 0.033 14.8 0.2 3.3 8.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDO05798.1 - 0.036 14.6 0.2 9.5 7.1 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EDO05798.1 - 0.97 9.6 4.6 40 4.4 2.9 3.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Myb_DNA-binding PF00249.26 EDO05799.1 - 0.0037 17.2 0.0 0.01 15.8 0.0 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF726 PF05277.7 EDO05800.1 - 6.5e-76 255.4 0.5 1.5e-75 254.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Cutinase PF01083.17 EDO05800.1 - 0.013 15.2 0.0 0.04 13.6 0.0 1.8 2 0 0 2 2 2 0 Cutinase DUF676 PF05057.9 EDO05800.1 - 0.044 13.0 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) VirJ PF06057.6 EDO05800.1 - 0.069 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 EDO05800.1 - 0.1 12.3 0.5 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family UQ_con PF00179.21 EDO05801.1 - 4.3e-53 178.4 0.1 4.9e-53 178.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO05801.1 - 1.9e-06 27.6 0.0 2.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDO05801.1 - 0.0013 18.5 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EDO05801.1 - 0.012 15.3 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 0 UEV domain NAP PF00956.13 EDO05802.1 - 3.7e-67 225.9 6.5 3.7e-67 225.9 4.5 1.8 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) FCH PF00611.18 EDO05802.1 - 0.05 13.7 0.1 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Phage_Mu_Gam PF07352.7 EDO05802.1 - 0.051 13.0 0.3 0.051 13.0 0.2 2.9 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein Mst1_SARAH PF11629.3 EDO05802.1 - 0.058 13.2 3.0 0.26 11.1 0.8 2.4 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Nucleoplasmin PF03066.10 EDO05802.1 - 0.33 10.4 4.5 0.51 9.8 3.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin Proteasome PF00227.21 EDO05803.1 - 1.7e-23 82.8 0.0 2.3e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit PCNA_N PF00705.13 EDO05804.1 - 9.1e-42 141.5 1.6 1.5e-41 140.8 1.1 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EDO05804.1 - 5.3e-25 87.7 0.0 9.8e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EDO05804.1 - 0.002 17.3 0.1 0.0026 16.9 0.0 1.1 1 0 0 1 1 1 1 Rad9 DUF106 PF01956.11 EDO05805.1 - 0.0027 17.2 0.0 0.0028 17.2 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 RhoGAP PF00620.22 EDO05805.1 - 0.096 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 RhoGAP domain TIP49 PF06068.8 EDO05806.1 - 1e-163 544.7 0.0 1.2e-163 544.4 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EDO05806.1 - 8.2e-08 32.5 0.0 5.3e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO05806.1 - 1.5e-06 28.3 0.0 0.0091 16.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EDO05806.1 - 2.5e-05 23.4 0.0 4.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EDO05806.1 - 2.8e-05 23.3 1.0 0.00031 19.9 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EDO05806.1 - 5.8e-05 23.1 0.2 0.00084 19.3 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EDO05806.1 - 0.00011 22.9 0.0 0.00045 21.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EDO05806.1 - 0.00082 19.6 0.1 0.0046 17.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.10 EDO05806.1 - 0.00084 18.2 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain RuvB_N PF05496.7 EDO05806.1 - 0.0014 17.7 2.9 0.009 15.0 0.0 3.0 4 0 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus CPT PF07931.7 EDO05806.1 - 0.0014 18.2 0.0 0.058 13.0 0.0 2.4 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.21 EDO05806.1 - 0.0031 17.0 0.1 0.15 11.5 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 EDO05806.1 - 0.0036 17.0 0.1 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EDO05806.1 - 0.0043 16.5 0.3 0.01 15.3 0.1 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EDO05806.1 - 0.0049 16.3 0.1 0.012 14.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO05806.1 - 0.0061 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Zot PF05707.7 EDO05806.1 - 0.034 13.6 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) NACHT PF05729.7 EDO05806.1 - 0.04 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KaiC PF06745.8 EDO05806.1 - 0.056 12.5 0.3 0.13 11.3 0.2 1.5 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.12 EDO05806.1 - 0.056 12.8 0.2 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 EDO05806.1 - 0.057 13.3 0.0 0.15 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EDO05806.1 - 0.063 12.8 0.0 8.2 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EDO05806.1 - 0.087 11.7 0.0 0.24 10.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF1053 PF06327.9 EDO05806.1 - 0.1 12.9 1.6 0.23 11.8 0.0 2.4 3 0 0 3 3 2 0 Domain of Unknown Function (DUF1053) DEAD PF00270.24 EDO05806.1 - 0.11 11.9 0.1 3.2 7.2 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase KfrA_N PF11740.3 EDO05808.1 - 0.0019 18.6 0.3 0.003 17.9 0.2 1.3 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term Transpep_BrtH PF14399.1 EDO05808.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase NYN PF01936.13 EDO05809.1 - 0.11 12.8 0.0 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 NYN domain DUF382 PF04037.8 EDO05811.1 - 1.9e-55 186.1 3.0 1.9e-55 186.1 2.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EDO05811.1 - 5.7e-24 83.2 5.0 1e-23 82.4 2.7 2.0 2 0 0 2 2 2 1 PSP GlutR_dimer PF00745.15 EDO05811.1 - 0.98 9.3 12.3 0.11 12.5 2.5 3.0 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain TPR_11 PF13414.1 EDO05812.1 - 8.5e-17 60.5 5.3 4.7e-11 42.1 0.8 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EDO05812.1 - 4.9e-10 38.5 2.3 0.0018 17.7 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO05812.1 - 5.3e-09 35.3 4.4 0.00081 19.1 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO05812.1 - 1.3e-05 25.0 4.2 0.0098 15.8 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO05812.1 - 9.4e-05 21.9 3.6 0.00043 19.8 0.5 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO05812.1 - 0.00017 22.1 6.1 0.0065 17.1 0.6 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDO05812.1 - 0.0027 17.7 1.4 0.056 13.6 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDO05812.1 - 0.027 14.3 0.5 0.099 12.5 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDO05812.1 - 0.44 10.4 2.9 14 5.7 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDO05812.1 - 0.44 11.3 4.0 8.2 7.3 0.2 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EDO05812.1 - 0.66 9.2 3.5 5.7 6.2 0.1 3.3 4 0 0 4 4 4 0 SHNi-TPR TPR_6 PF13174.1 EDO05812.1 - 0.89 10.1 4.5 9.2 6.9 0.7 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.24 EDO05813.1 - 1.1e-13 51.0 0.0 1.4e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDO05813.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EDO05813.1 - 0.053 12.8 0.0 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF4137 PF13593.1 EDO05813.1 - 0.064 12.3 0.0 0.064 12.3 0.0 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) PhoH PF02562.11 EDO05813.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein TPR_11 PF13414.1 EDO05816.1 - 2.6e-07 30.1 1.0 3.6e-07 29.7 0.7 1.2 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 EDO05816.1 - 0.0056 17.3 0.6 0.0079 16.8 0.4 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDO05816.1 - 0.011 15.3 0.1 2.3 7.9 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDO05816.1 - 0.013 15.3 0.2 0.098 12.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.24 EDO05817.1 - 5.1e-32 110.6 1.0 8.5e-32 109.9 0.7 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO05817.1 - 6.6e-15 54.7 0.1 2.1e-14 53.0 0.1 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO05817.1 - 4e-06 26.8 0.1 8.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EDO05817.1 - 0.00076 18.5 0.1 0.0013 17.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EDO05817.1 - 0.0029 17.7 0.2 0.017 15.2 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EDO05817.1 - 0.045 13.5 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EDO05818.1 - 2e-15 57.1 0.0 4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EDO05818.1 - 1.4e-14 53.8 0.5 9.5e-14 51.1 0.0 2.3 2 1 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EDO05818.1 - 1.9e-12 47.1 0.1 1.2e-10 41.3 0.1 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EDO05818.1 - 1.6e-08 33.7 0.1 0.00019 20.2 0.1 2.3 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EDO05818.1 - 1.2e-07 31.6 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO05818.1 - 4.6e-07 30.0 0.0 0.00019 21.4 0.0 2.7 2 1 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.7 EDO05818.1 - 1.1e-06 27.8 0.1 5.3e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EDO05818.1 - 1.8e-06 27.2 0.0 5e-05 22.5 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EDO05818.1 - 2.5e-06 27.6 0.5 0.021 14.9 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 EDO05818.1 - 1.9e-05 24.3 0.0 4.9e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EDO05818.1 - 0.00016 21.3 0.0 0.00046 19.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 EDO05818.1 - 0.00016 21.2 0.2 0.00027 20.4 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.1 EDO05818.1 - 0.00041 19.9 0.0 0.00054 19.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EDO05818.1 - 0.00047 19.7 0.2 0.006 16.0 0.0 2.2 1 1 1 2 2 2 1 FtsK/SpoIIIE family DEAD PF00270.24 EDO05818.1 - 0.00063 19.2 0.1 0.23 10.9 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase NTPase_1 PF03266.10 EDO05818.1 - 0.0012 18.6 0.9 1.2 8.8 0.1 2.3 1 1 0 2 2 2 2 NTPase IstB_IS21 PF01695.12 EDO05818.1 - 0.002 17.5 0.2 0.0064 15.9 0.1 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EDO05818.1 - 0.002 18.1 0.0 0.0076 16.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_10 PF12846.2 EDO05818.1 - 0.0023 17.4 0.1 0.018 14.5 0.1 2.2 1 1 0 1 1 1 1 AAA-like domain AAA_3 PF07726.6 EDO05818.1 - 0.0026 17.3 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDO05818.1 - 0.0048 16.3 0.1 0.015 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EDO05818.1 - 0.0074 15.8 0.0 0.015 14.7 0.0 1.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 EDO05818.1 - 0.01 14.6 0.2 0.27 9.9 0.0 2.1 1 1 1 2 2 2 1 TIP49 C-terminus SRP54 PF00448.17 EDO05818.1 - 0.026 13.9 0.0 0.06 12.7 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.1 EDO05818.1 - 0.028 14.7 0.1 0.089 13.1 0.0 1.9 1 1 0 2 2 2 0 AAA domain MCM PF00493.18 EDO05818.1 - 0.031 13.0 0.1 0.075 11.8 0.1 1.7 1 1 0 1 1 1 0 MCM2/3/5 family RNA_helicase PF00910.17 EDO05818.1 - 0.032 14.3 0.0 0.14 12.3 0.0 2.1 1 1 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EDO05818.1 - 0.033 14.0 0.2 0.059 13.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EDO05818.1 - 0.035 12.9 0.4 3.7 6.2 0.0 2.2 1 1 0 2 2 2 0 SNF2 family N-terminal domain KTI12 PF08433.5 EDO05818.1 - 0.054 12.7 0.0 0.12 11.6 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 PhoH PF02562.11 EDO05818.1 - 0.084 12.0 0.0 4.7 6.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 EDO05818.1 - 0.12 11.8 0.0 6.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ArgK PF03308.11 EDO05818.1 - 0.12 11.1 0.1 0.47 9.1 0.0 1.9 2 1 1 3 3 3 0 ArgK protein RBFA PF02033.13 EDO05819.1 - 6.1e-12 45.4 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Ribosome-binding factor A RseA_C PF03873.8 EDO05819.1 - 0.037 13.8 0.6 0.037 13.8 0.4 2.2 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain S4 PF01479.20 EDO05820.1 - 4.5e-09 35.6 0.1 9.1e-09 34.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_L22e PF01776.12 EDO05820.1 - 0.42 10.6 4.8 0.86 9.6 3.3 1.5 1 0 0 1 1 1 0 Ribosomal L22e protein family Ribosomal_S28e PF01200.13 EDO05821.1 - 8.4e-32 108.7 2.1 9e-32 108.6 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MORN PF02493.15 EDO05825.1 - 4.9e-28 95.1 38.5 3.9e-06 26.2 0.1 8.1 7 1 0 7 7 7 7 MORN repeat SM-ATX PF14438.1 EDO05825.1 - 0.057 13.3 3.8 2.9 7.9 0.1 4.3 3 1 1 4 4 4 0 Ataxin 2 SM domain ParA PF10609.4 EDO05826.1 - 9.9e-24 83.0 0.3 2e-23 82.0 0.2 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EDO05826.1 - 5.6e-16 58.5 0.0 7.6e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EDO05826.1 - 5e-08 33.0 0.0 1.5e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EDO05826.1 - 6.9e-06 25.3 0.4 2.9e-05 23.2 0.1 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EDO05826.1 - 0.00013 21.1 0.1 0.00061 18.9 0.1 1.9 1 1 0 1 1 1 1 ATPase MipZ AAA_17 PF13207.1 EDO05826.1 - 0.0048 17.7 0.0 0.01 16.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDO05826.1 - 0.0073 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EDO05826.1 - 0.0084 14.9 0.3 0.024 13.5 0.1 1.7 2 0 0 2 2 2 1 NB-ARC domain DUF258 PF03193.11 EDO05826.1 - 0.012 14.8 0.2 0.023 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ArgK PF03308.11 EDO05826.1 - 0.014 14.1 0.2 0.022 13.5 0.1 1.2 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 EDO05826.1 - 0.019 15.2 0.0 0.065 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EDO05826.1 - 0.026 13.7 0.1 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EDO05826.1 - 0.032 14.2 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EDO05826.1 - 0.054 13.2 0.1 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_26 PF13500.1 EDO05826.1 - 0.16 11.5 0.2 2.9 7.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain DNA_primase_lrg PF04104.9 EDO05827.1 - 3.7e-62 209.9 0.0 5.7e-62 209.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Prenyltransf PF01255.14 EDO05828.1 - 1.3e-59 201.0 0.0 1.4e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase SET PF00856.23 EDO05829.1 - 4.5e-23 82.3 0.3 1.9e-22 80.3 0.2 2.0 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EDO05829.1 - 2.1e-12 47.1 1.2 5.6e-12 45.8 0.8 1.8 1 0 0 1 1 1 1 Pre-SET motif SAD_SRA PF02182.12 EDO05829.1 - 3.6e-10 39.3 0.0 5.9e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain Thioredoxin PF00085.15 EDO05830.1 - 2e-47 159.1 0.0 3e-27 94.3 0.0 3.7 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EDO05830.1 - 1.5e-30 106.3 0.1 5.9e-19 68.5 0.3 4.2 2 2 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDO05830.1 - 1.4e-12 47.5 0.0 3.9e-05 23.6 0.0 4.3 4 1 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EDO05830.1 - 2e-10 40.8 0.7 9.8e-05 22.5 0.1 4.5 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EDO05830.1 - 6.2e-09 35.6 0.0 0.0037 16.9 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.1 EDO05830.1 - 6.9e-07 29.2 0.0 0.018 15.0 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.5 EDO05830.1 - 0.0016 18.0 0.1 0.098 12.1 0.0 2.7 3 0 0 3 3 3 1 Redoxin 2OG-FeII_Oxy_3 PF13640.1 EDO05831.1 - 3e-08 34.0 0.4 1.3e-06 28.7 0.0 2.5 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EDO05831.1 - 9e-07 29.1 0.1 3.8e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EDO05831.1 - 1.4e-05 24.6 0.2 4.7e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily LSM PF01423.17 EDO05832.1 - 2.6e-15 55.7 0.0 3.2e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain tRNA-synt_1 PF00133.17 EDO05834.1 - 5.8e-40 136.8 3.2 3e-25 88.3 0.0 5.7 3 2 3 6 6 6 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EDO05834.1 - 6.9e-26 90.8 0.0 4.9e-17 61.6 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EDO05834.1 - 5.8e-10 39.1 0.1 1.8e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 EDO05834.1 - 1.1e-06 28.0 0.0 1.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EDO05834.1 - 0.0007 18.8 0.1 0.029 13.4 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain UPF0542 PF15086.1 EDO05834.1 - 0.079 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 ubiquitin PF00240.18 EDO05836.1 - 3.1e-13 48.9 0.0 5.3e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EDO05836.1 - 7.4e-09 35.1 0.1 2e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDO05836.1 - 0.00013 22.1 0.0 0.0004 20.5 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EDO05836.1 - 0.013 15.3 0.0 0.061 13.2 0.0 2.0 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Methyltransf_11 PF08241.7 EDO05837.1 - 1.8e-14 53.9 0.0 2.7e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO05837.1 - 1.4e-09 37.3 0.0 1.8e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EDO05837.1 - 9.3e-07 28.5 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO05837.1 - 2e-06 27.6 0.0 2.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO05837.1 - 2.3e-06 27.9 0.0 4.6e-06 26.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO05837.1 - 0.018 15.4 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Tim17 PF02466.14 EDO05838.1 - 5.5e-26 91.1 3.3 6.4e-26 90.8 2.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ERO1 PF04137.10 EDO05839.1 - 3.9e-65 220.2 0.0 4.9e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Beach PF02138.13 EDO05840.1 - 1.8e-80 270.2 0.1 2.6e-80 269.7 0.1 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EDO05840.1 - 0.00074 19.3 0.0 0.00074 19.3 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat FIST PF08495.5 EDO05840.1 - 0.051 12.7 0.0 0.14 11.3 0.0 1.7 1 0 0 1 1 1 0 FIST N domain 60KD_IMP PF02096.15 EDO05841.1 - 6.4e-12 45.5 7.2 2.3e-11 43.7 5.0 1.8 1 1 0 1 1 1 1 60Kd inner membrane protein RVT_N PF13655.1 EDO05841.1 - 0.078 13.0 0.5 0.21 11.6 0.3 1.7 1 0 0 1 1 1 0 N-terminal domain of reverse transcriptase Band_7 PF01145.20 EDO05842.1 - 1.9e-28 99.5 1.3 3.3e-28 98.8 0.4 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family BT1 PF03092.11 EDO05843.1 - 2e-70 237.6 16.7 3e-70 237.1 11.6 1.2 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 EDO05843.1 - 2.7e-11 42.8 23.4 1.3e-05 24.1 6.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily FliH PF02108.11 EDO05844.1 - 0.053 13.4 0.2 0.053 13.4 0.1 1.9 2 0 0 2 2 2 0 Flagellar assembly protein FliH DUF1767 PF08585.7 EDO05845.1 - 0.13 12.5 0.1 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1767) Prok-RING_1 PF14446.1 EDO05846.1 - 0.0015 18.2 1.2 0.0026 17.4 0.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-UDP PF14569.1 EDO05846.1 - 0.0048 16.6 0.5 0.011 15.4 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger DZR PF12773.2 EDO05846.1 - 0.0063 16.3 3.3 0.01 15.6 2.3 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_4 PF13717.1 EDO05846.1 - 0.016 14.8 3.7 0.15 11.8 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain TerY-C PF15616.1 EDO05846.1 - 0.018 14.9 0.8 0.037 13.9 0.5 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zinc_ribbon_5 PF13719.1 EDO05846.1 - 0.032 13.8 4.5 0.14 11.7 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.1 EDO05846.1 - 0.078 12.5 3.4 0.15 11.6 2.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Glutaredoxin PF00462.19 EDO05846.1 - 0.14 12.1 0.8 3.5 7.6 0.0 3.2 3 1 0 3 3 3 0 Glutaredoxin ADK_lid PF05191.9 EDO05846.1 - 0.27 10.9 3.4 0.83 9.3 0.2 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid CpXC PF14353.1 EDO05846.1 - 1.1 9.2 4.2 1.5 8.8 0.2 2.4 1 1 1 2 2 2 0 CpXC protein PPR_2 PF13041.1 EDO05847.1 - 8.5e-66 217.7 26.8 2e-14 53.2 0.2 9.4 1 1 8 9 9 9 8 PPR repeat family PPR PF01535.15 EDO05847.1 - 4.1e-50 164.3 24.1 2.2e-08 33.5 0.1 11.4 11 0 0 11 11 11 9 PPR repeat PPR_3 PF13812.1 EDO05847.1 - 1e-48 159.5 3.3 1.4e-06 28.1 0.1 11.8 12 0 0 12 12 12 7 Pentatricopeptide repeat domain PPR_1 PF12854.2 EDO05847.1 - 1.4e-48 162.0 16.0 5.9e-08 32.0 0.1 9.5 10 0 0 10 10 10 8 PPR repeat TPR_14 PF13428.1 EDO05847.1 - 0.0017 18.8 0.1 56 4.7 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat ATP13 PF12921.2 EDO05847.1 - 0.0023 17.2 0.1 2.6 7.3 0.0 4.2 3 1 0 4 4 4 1 Mitochondrial ATPase expression ECSIT PF06239.6 EDO05847.1 - 0.0058 15.5 1.2 3.1 6.5 0.0 3.3 2 1 1 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway TPR_7 PF13176.1 EDO05847.1 - 0.024 14.4 0.0 3.6 7.6 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EDO05847.1 - 0.046 13.8 1.7 50 4.1 0.0 4.6 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 MRP-S27 PF10037.4 EDO05847.1 - 0.13 11.1 0.1 0.34 9.7 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Brix PF04427.13 EDO05849.1 - 4.7e-38 130.7 0.6 6.6e-38 130.2 0.4 1.2 1 0 0 1 1 1 1 Brix domain DUF2691 PF10903.3 EDO05849.1 - 0.049 13.4 0.0 5 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2691) EF-hand_8 PF13833.1 EDO05849.1 - 0.078 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair ParG PF09274.5 EDO05849.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 ParG Gaa1 PF04114.9 EDO05850.1 - 0.00048 18.9 0.0 0.00048 18.9 0.0 2.1 3 0 0 3 3 3 1 Gaa1-like, GPI transamidase component Vps36_ESCRT-II PF11605.3 EDO05851.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 ERCC4 PF02732.10 EDO05852.1 - 9.1e-22 77.3 0.5 6.4e-21 74.6 0.0 2.6 3 0 0 3 3 3 1 ERCC4 domain OB_NTP_bind PF07717.11 EDO05853.1 - 9.1e-25 86.7 0.0 2.5e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EDO05853.1 - 1.6e-21 76.2 0.0 4.9e-21 74.6 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDO05853.1 - 6.5e-11 41.9 0.0 3.8e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO05853.1 - 1.6e-06 27.7 0.0 3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDO05853.1 - 8e-06 26.0 0.0 2.4e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDO05853.1 - 0.003 17.4 0.1 0.066 13.1 0.1 2.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EDO05853.1 - 0.011 15.6 0.0 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EDO05853.1 - 0.016 14.0 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 EDO05853.1 - 0.016 14.2 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 EDO05853.1 - 0.037 12.9 0.0 0.075 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 EDO05853.1 - 0.039 13.4 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EDO05853.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.9 EDO05853.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Miro PF08477.8 EDO05853.1 - 0.11 13.0 0.0 0.51 10.8 0.0 2.2 1 0 0 1 1 1 0 Miro-like protein NUC173 PF08161.7 EDO05854.1 - 3.4e-07 29.8 0.1 3e-06 26.7 0.0 2.6 2 0 0 2 2 2 1 NUC173 domain CTD_bind PF04818.8 EDO05856.1 - 0.00038 20.6 0.1 0.0011 19.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF87 PF01935.12 EDO05858.1 - 0.0083 15.9 0.8 0.026 14.3 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function DUF87 DUF4602 PF15375.1 EDO05859.1 - 5.2e-12 45.9 8.8 1.2e-11 44.8 6.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) tRNA-synt_2 PF00152.15 EDO05860.1 - 2.1e-82 276.6 0.0 2.7e-82 276.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDO05860.1 - 5.4e-11 42.2 0.1 1.4e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EDO05860.1 - 2.7e-09 36.5 0.1 1.9e-05 24.0 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EDO05860.1 - 0.0054 16.3 0.0 2.8 7.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) LSM PF01423.17 EDO05861.1 - 3.6e-15 55.2 0.0 4.1e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.15 EDO05862.1 - 1.5e-43 148.3 0.1 2.6e-43 147.5 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease ERCC4 PF02732.10 EDO05864.1 - 2.1e-18 66.4 0.0 1.2e-17 64.0 0.0 2.0 1 1 0 1 1 1 1 ERCC4 domain DUF2959 PF11172.3 EDO05865.1 - 0.0025 17.6 1.4 3 7.5 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF2959) SNARE PF05739.14 EDO05865.1 - 0.022 14.4 0.4 0.022 14.4 0.3 2.1 3 0 0 3 3 3 0 SNARE domain Syntaxin-6_N PF09177.6 EDO05865.1 - 0.023 15.1 1.7 0.22 11.9 0.2 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.1 EDO05865.1 - 0.03 14.3 2.1 0.099 12.6 0.1 2.2 2 1 0 2 2 2 0 Syntaxin-like protein Vhr1 PF04001.8 EDO05865.1 - 0.14 12.0 1.5 0.63 9.9 0.1 2.6 3 1 0 3 3 3 0 Transcription factor Vhr1 Laminin_II PF06009.7 EDO05865.1 - 0.18 11.5 2.2 0.86 9.3 0.1 2.6 2 1 0 2 2 2 0 Laminin Domain II V-SNARE PF05008.10 EDO05865.1 - 0.34 11.1 2.3 4.7 7.4 0.1 3.3 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF818 PF05677.7 EDO05867.1 - 0.00095 17.9 0.0 0.0015 17.3 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Xpo1 PF08389.7 EDO05868.1 - 3e-05 23.9 4.3 4.7e-05 23.3 0.1 3.5 4 1 1 5 5 5 1 Exportin 1-like protein TFIIB PF00382.14 EDO05869.1 - 5.8e-25 86.9 0.5 4.4e-13 48.8 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EDO05869.1 - 4.4e-19 68.5 4.3 7.6e-19 67.7 3.0 1.4 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EDO05869.1 - 5.6e-07 28.7 1.5 1.2e-06 27.6 1.1 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 EDO05869.1 - 7.2e-05 22.1 6.5 0.00012 21.4 3.8 1.9 2 0 0 2 2 2 1 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 EDO05869.1 - 0.062 12.5 4.7 0.032 13.4 1.4 2.0 2 0 0 2 2 2 0 zinc-ribbon domain E1-E2_ATPase PF00122.15 EDO05870.1 - 8e-22 77.4 1.2 1.2e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EDO05870.1 - 7.2e-17 62.5 0.1 1.4e-15 58.3 0.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDO05870.1 - 1.5e-14 54.5 0.0 4e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDO05870.1 - 0.0076 15.6 0.3 0.06 12.8 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EDO05870.1 - 0.023 14.6 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DEAD PF00270.24 EDO05872.1 - 5.2e-36 123.6 0.0 8.3e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO05872.1 - 2.1e-25 88.3 0.0 1.2e-24 85.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EDO05872.1 - 0.067 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_L37ae PF01780.14 EDO05873.1 - 2.2e-36 123.5 6.1 2.5e-36 123.4 4.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EDO05873.1 - 0.00019 21.1 3.5 0.00027 20.6 2.4 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Lar_restr_allev PF14354.1 EDO05873.1 - 0.0074 16.5 0.6 0.017 15.3 0.4 1.6 1 1 0 1 1 1 1 Restriction alleviation protein Lar A2L_zn_ribbon PF08792.5 EDO05873.1 - 0.017 14.5 1.8 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-BED PF02892.10 EDO05873.1 - 0.027 14.2 3.1 0.59 9.9 0.2 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.1 EDO05873.1 - 0.051 13.8 1.9 0.51 10.7 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Elf1 PF05129.8 EDO05873.1 - 0.053 13.2 1.7 0.14 11.8 1.1 1.8 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2_4 PF13894.1 EDO05873.1 - 0.11 12.9 0.9 4.2 7.9 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger OrfB_Zn_ribbon PF07282.6 EDO05873.1 - 0.11 12.1 0.8 0.17 11.5 0.5 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Prim_Zn_Ribbon PF08273.7 EDO05873.1 - 0.9 9.6 4.0 1.5 8.9 2.7 1.4 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Zn-ribbon_8 PF09723.5 EDO05873.1 - 2.7 8.0 4.8 2.7 8.0 0.1 2.2 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2 PF00096.21 EDO05873.1 - 4.2 7.9 6.8 1.7 9.1 0.2 2.5 3 0 0 3 3 2 0 Zinc finger, C2H2 type SecE PF00584.15 EDO05874.1 - 6.1e-12 44.9 0.1 7.8e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Sec20 PF03908.8 EDO05874.1 - 0.086 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Sec20 SNF PF00209.13 EDO05875.1 - 6.3e-12 44.7 29.6 6.3e-12 44.7 20.5 2.1 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family NAD_kinase PF01513.16 EDO05877.1 - 2e-54 184.3 0.7 5.1e-54 182.9 0.5 1.6 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EDO05877.1 - 0.00021 20.7 0.2 0.00047 19.5 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain YgbB PF02542.11 EDO05878.1 - 8.1e-48 162.2 0.2 9.5e-48 161.9 0.1 1.1 1 0 0 1 1 1 1 YgbB family ApoC-I PF04691.7 EDO05878.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) zf-RING_2 PF13639.1 EDO05879.1 - 0.05 13.4 2.0 0.25 11.1 1.4 2.0 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 EDO05879.1 - 0.12 12.2 1.3 1.6 8.6 0.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EDO05879.1 - 0.12 11.9 1.2 1.7 8.4 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RBP_receptor PF14752.1 EDO05880.1 - 0.00081 17.8 0.1 0.71 8.1 0.0 2.2 2 0 0 2 2 2 2 Retinol binding protein receptor DUF308 PF03729.8 EDO05880.1 - 0.014 15.3 5.7 1.7 8.6 0.4 2.7 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF3989 PF13150.1 EDO05880.1 - 0.29 10.5 0.1 18 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) DUF2530 PF10745.4 EDO05880.1 - 1.6 8.7 8.2 13 5.8 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) VESA1_N PF12785.2 EDO05881.1 - 4.4e-21 75.3 28.8 9.5e-19 67.7 10.0 4.6 2 1 1 3 3 3 1 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05882.1 - 2.1e-195 650.1 22.6 9.5e-131 436.9 0.9 3.3 2 1 1 3 3 3 2 Variant erythrocyte surface antigen-1 RBP_receptor PF14752.1 EDO05883.1 - 0.0014 17.0 0.1 0.0014 17.0 0.1 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor UPF0020 PF01170.13 EDO05885.1 - 7.3e-13 48.4 0.0 3.8e-07 29.8 0.0 2.6 2 1 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EDO05885.1 - 6e-11 42.3 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EDO05885.1 - 1.3e-06 28.0 0.0 0.0033 16.9 0.0 2.4 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.11 EDO05885.1 - 0.033 13.2 0.0 0.16 10.9 0.0 2.0 1 1 0 1 1 1 0 N-6 DNA Methylase DUF1764 PF08576.5 EDO05886.1 - 6.1e-27 94.3 2.2 7.7e-27 94.0 1.3 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) DUF1014 PF06244.7 EDO05886.1 - 0.16 12.1 2.9 0.22 11.7 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) EFP PF01132.15 EDO05887.1 - 0.00011 21.7 0.1 0.00018 21.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Ras PF00071.17 EDO05888.1 - 1.7e-57 193.3 0.1 2e-57 193.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO05888.1 - 5.4e-19 68.8 0.0 9.5e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO05888.1 - 2.6e-13 49.5 0.0 3.4e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDO05888.1 - 6.6e-06 25.6 0.1 5.9e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO05888.1 - 0.00055 19.8 0.0 0.00083 19.3 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EDO05888.1 - 0.0024 17.0 0.0 0.0032 16.6 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 EDO05888.1 - 0.045 13.5 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Dynamin family DUF258 PF03193.11 EDO05888.1 - 0.091 11.9 0.0 0.32 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 TP_methylase PF00590.15 EDO05889.1 - 3.2e-25 89.0 0.1 4.7e-25 88.5 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PetM PF08041.6 EDO05889.1 - 1.3 8.5 3.3 2.8 7.4 2.3 1.6 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 ADK PF00406.17 EDO05890.1 - 2.7e-51 173.3 0.0 3.5e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EDO05890.1 - 8.5e-13 47.7 0.0 2.2e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EDO05890.1 - 4.8e-06 26.4 0.0 9.7e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO05890.1 - 4.9e-05 23.6 0.0 9.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO05890.1 - 0.0035 18.1 0.0 0.0085 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain zf-C2H2_4 PF13894.1 EDO05891.1 - 0.00031 20.8 2.3 0.21 12.0 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDO05891.1 - 0.0021 18.1 4.7 0.7 10.1 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EDO05891.1 - 0.0037 17.5 2.7 0.31 11.4 0.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 EDO05891.1 - 0.028 14.5 3.8 2.5 8.2 0.3 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.17 EDO05891.1 - 0.27 11.3 3.3 0.49 10.4 2.3 1.4 1 0 0 1 1 1 0 LIM domain zf-C2H2_6 PF13912.1 EDO05891.1 - 0.37 10.7 3.5 3.2 7.7 0.0 2.6 1 1 1 2 2 2 0 C2H2-type zinc finger AMP-binding PF00501.23 EDO05892.1 - 5.7e-05 21.6 0.0 9.1e-05 21.0 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme Beta-Casp PF10996.3 EDO05893.1 - 0.0046 16.8 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain TBP PF00352.16 EDO05894.1 - 1.5e-61 203.7 0.5 5.9e-30 102.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) MIF4G PF02854.14 EDO05895.1 - 1e-22 80.5 0.1 1.5e-22 80.0 0.1 1.2 1 0 0 1 1 1 1 MIF4G domain WD40 PF00400.27 EDO05898.1 - 0.01 15.7 2.9 0.042 13.7 0.1 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat Myb_DNA-binding PF00249.26 EDO05900.1 - 5e-19 68.0 5.6 2.8e-10 40.1 0.2 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO05900.1 - 2.9e-16 59.2 3.2 3.1e-11 43.2 1.8 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_Cef PF11831.3 EDO05900.1 - 4.4e-14 52.2 0.7 4.4e-14 52.2 0.5 2.9 3 1 0 3 3 3 1 pre-mRNA splicing factor component RAP PF08373.5 EDO05901.1 - 1.7e-16 59.7 2.6 4.1e-16 58.5 1.8 1.6 1 0 0 1 1 1 1 RAP domain DUF559 PF04480.7 EDO05901.1 - 0.00024 20.7 0.1 0.00058 19.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF559) FAST_1 PF06743.10 EDO05901.1 - 0.12 12.0 1.8 0.91 9.2 0.1 2.6 2 1 1 3 3 3 0 FAST kinase-like protein, subdomain 1 MORN PF02493.15 EDO05903.1 - 1e-29 100.4 15.2 1.7e-06 27.3 0.1 7.7 7 0 0 7 7 7 7 MORN repeat Rep_fac_C PF08542.6 EDO05904.1 - 8.5e-17 60.9 0.0 5.3e-16 58.3 0.0 2.2 2 1 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EDO05904.1 - 2.5e-10 40.2 0.0 4.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 EDO05904.1 - 0.00025 21.1 0.2 0.056 13.4 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain Rad17 PF03215.10 EDO05904.1 - 0.0027 16.4 0.1 0.02 13.6 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 EDO05904.1 - 0.016 13.9 0.7 0.18 10.4 0.3 2.0 2 0 0 2 2 2 0 TIP49 C-terminus RuvB_N PF05496.7 EDO05904.1 - 0.067 12.2 0.5 0.47 9.4 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Prenyltrans_2 PF13249.1 EDO05904.1 - 0.098 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Prenyltransferase-like FF PF01846.14 EDO05905.1 - 1.2e-09 37.9 3.5 1.1e-06 28.4 0.2 3.6 4 0 0 4 4 4 2 FF domain WW PF00397.21 EDO05905.1 - 1.8e-05 24.4 2.2 3e-05 23.7 1.5 1.4 1 0 0 1 1 1 1 WW domain Not1 PF04054.10 EDO05906.1 - 1.1e-38 133.0 0.3 9.3e-28 97.1 0.0 2.8 3 0 0 3 3 3 2 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EDO05906.1 - 3.6e-38 130.5 3.6 7.5e-38 129.5 2.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) zf-CHY PF05495.7 EDO05907.1 - 2.6e-16 59.5 13.3 2.6e-16 59.5 9.2 3.9 4 0 0 4 4 4 2 CHY zinc finger Myb_DNA-binding PF00249.26 EDO05907.1 - 0.003 17.5 0.0 0.0066 16.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO05907.1 - 0.071 13.2 0.4 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain HD_3 PF13023.1 EDO05908.1 - 0.026 14.2 2.0 0.042 13.5 1.4 1.3 1 0 0 1 1 1 0 HD domain Lin-8 PF03353.10 EDO05908.1 - 0.16 11.2 7.1 0.21 10.8 4.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist HALZ PF02183.13 EDO05909.1 - 0.0024 17.5 0.5 0.005 16.5 0.3 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF2786 PF10979.3 EDO05910.1 - 0.035 13.8 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) DnaJ PF00226.26 EDO05910.1 - 0.069 12.8 0.2 0.19 11.4 0.1 1.8 1 1 0 1 1 1 0 DnaJ domain Thioredoxin_8 PF13905.1 EDO05911.1 - 6e-16 58.3 0.0 8.4e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EDO05911.1 - 8.2e-07 28.7 0.0 9.3e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EDO05911.1 - 7e-05 22.4 0.0 8.8e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin Ski_Sno PF02437.12 EDO05911.1 - 0.04 13.4 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 SKI/SNO/DAC family SNARE_assoc PF09335.6 EDO05912.1 - 1.6e-16 60.6 13.9 1.6e-16 60.6 9.6 2.2 2 1 1 3 3 3 1 SNARE associated Golgi protein Orbi_NS3 PF01616.11 EDO05912.1 - 0.41 9.5 1.5 0.8 8.6 1.1 1.4 1 0 0 1 1 1 0 Orbivirus NS3 CoA_binding_3 PF13727.1 EDO05912.1 - 0.6 9.9 10.8 0.19 11.5 1.8 2.7 1 1 2 3 3 3 0 CoA-binding domain Sugar_tr PF00083.19 EDO05913.1 - 6.4e-67 226.0 38.4 1.4e-66 224.9 26.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO05913.1 - 1.5e-18 66.6 33.9 1.5e-18 66.6 23.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EDO05913.1 - 0.00029 19.1 7.1 0.00029 19.1 5.0 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3302 PF11742.3 EDO05913.1 - 0.0021 17.8 2.0 1.7 8.5 0.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3302) Sugar_tr PF00083.19 EDO05914.1 - 3e-61 207.3 22.6 3.5e-44 151.1 6.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDO05914.1 - 5e-20 71.5 8.9 5e-20 71.5 6.2 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EDO05914.1 - 0.0023 16.3 1.5 0.0023 16.3 1.0 3.5 2 2 1 3 3 3 2 MFS/sugar transport protein DUF2985 PF11204.3 EDO05914.1 - 0.031 14.0 0.8 0.12 12.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) TPR_19 PF14559.1 EDO05914.1 - 0.12 12.7 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat ubiquitin PF00240.18 EDO05915.1 - 1.8e-35 120.1 0.5 2.3e-35 119.8 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EDO05915.1 - 1.5e-29 101.3 9.4 2.4e-29 100.6 6.5 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EDO05915.1 - 1.4e-20 72.7 0.4 1.9e-20 72.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDO05915.1 - 2.1e-06 27.9 0.1 7.1e-06 26.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDO05915.1 - 0.0003 20.5 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDO05915.1 - 0.0065 16.3 0.0 0.016 15.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDO05915.1 - 0.024 14.8 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EDO05915.1 - 0.058 13.3 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 GLUT4 regulating protein TUG zf-CHY PF05495.7 EDO05915.1 - 0.33 11.1 4.9 0.51 10.5 3.4 1.2 1 0 0 1 1 1 0 CHY zinc finger Fer2_3 PF13085.1 EDO05915.1 - 5.6 6.8 6.2 8.4 6.2 0.0 2.5 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain TrmB PF01978.14 EDO05916.1 - 2.6e-05 23.8 0.4 0.0001 21.8 0.1 2.1 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 EDO05916.1 - 0.0011 18.7 0.0 0.0027 17.5 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_24 PF13412.1 EDO05916.1 - 0.0014 17.9 0.1 0.0014 17.9 0.1 2.1 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding DUF4423 PF14394.1 EDO05916.1 - 0.0017 17.9 0.3 0.0099 15.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) HTH_20 PF12840.2 EDO05916.1 - 0.0055 16.4 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain GntR PF00392.16 EDO05916.1 - 0.0084 15.5 0.2 0.023 14.1 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FaeA PF04703.7 EDO05916.1 - 0.015 15.4 0.1 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 FaeA-like protein FeoC PF09012.5 EDO05916.1 - 0.022 14.4 0.0 0.11 12.2 0.0 2.2 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_45 PF14947.1 EDO05916.1 - 0.052 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_5 PF01022.15 EDO05916.1 - 0.093 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family PaaX PF07848.7 EDO05916.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 PaaX-like protein Pkinase PF00069.20 EDO05917.1 - 3.9e-80 268.7 0.1 5.1e-80 268.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO05917.1 - 2e-42 145.0 0.0 2.8e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EDO05917.1 - 3.3e-28 94.7 11.2 7.7e-07 27.9 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EDO05917.1 - 1.5e-24 85.8 11.8 3.5e-12 46.2 1.4 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EDO05917.1 - 2.5e-22 77.1 11.8 1.1e-06 27.6 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EDO05917.1 - 4.9e-22 75.7 10.0 1.4e-06 27.6 0.0 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 EDO05917.1 - 1.2e-18 66.4 12.3 9.8e-06 25.0 0.4 4.6 1 1 3 4 4 4 4 EF-hand domain pair Kinase-like PF14531.1 EDO05917.1 - 8.6e-07 28.1 0.0 0.018 14.0 0.0 3.1 3 0 0 3 3 3 3 Kinase-like SPARC_Ca_bdg PF10591.4 EDO05917.1 - 1.2e-05 25.2 0.1 0.06 13.3 0.0 2.8 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.9 EDO05917.1 - 2.1e-05 23.7 0.0 5.5e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO05917.1 - 0.0012 18.6 0.0 0.025 14.3 0.0 2.4 2 1 0 3 3 3 1 Phosphotransferase enzyme family EF-hand_4 PF12763.2 EDO05917.1 - 0.0029 17.3 7.3 0.45 10.2 0.4 4.1 2 1 2 4 4 4 1 Cytoskeletal-regulatory complex EF hand Hydrolase_3 PF08282.7 EDO05918.1 - 1.8e-38 132.5 1.7 2.1e-38 132.3 1.1 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EDO05918.1 - 1.7e-05 24.2 0.0 0.03 13.6 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Acid_phosphat_B PF03767.9 EDO05918.1 - 0.037 13.3 1.8 1.9 7.8 0.1 2.9 2 2 1 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_3 PF08282.7 EDO05919.1 - 6.9e-38 130.6 0.0 8.9e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EDO05919.1 - 3.1e-08 33.2 0.0 2.7e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EDO05919.1 - 0.00047 20.6 0.0 0.059 13.7 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDO05919.1 - 0.0007 19.8 0.5 0.0017 18.5 0.4 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.3 EDO05919.1 - 0.0055 15.7 0.0 0.016 14.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2608) Hydrolase_3 PF08282.7 EDO05920.1 - 7.2e-34 117.4 0.0 8.7e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EDO05920.1 - 1.2e-07 31.3 0.0 0.0012 18.1 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EDO05920.1 - 0.0013 18.9 0.7 0.0022 18.2 0.5 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3756 PF12581.3 EDO05921.1 - 0.093 12.4 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) DUF4662 PF15578.1 EDO05922.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) NAP PF00956.13 EDO05923.1 - 7.9e-35 120.1 2.2 1.1e-34 119.7 1.5 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Inhibitor_I71 PF12628.2 EDO05924.1 - 0.00073 19.2 0.0 0.021 14.4 0.0 2.0 1 1 0 1 1 1 1 Falstatin, cysteine peptidase inhibitor Inhibitor_I42 PF09394.5 EDO05924.1 - 0.036 14.3 0.0 5 7.5 0.0 2.3 1 1 1 2 2 2 0 Chagasin family peptidase inhibitor I42 GTP_EFTU PF00009.22 EDO05925.1 - 2.7e-52 176.9 0.0 5.2e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EDO05925.1 - 1.1e-15 57.2 0.0 2.5e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EDO05925.1 - 2.2e-06 27.4 0.0 4.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EDO05925.1 - 0.0018 18.3 0.0 0.0046 17.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EDO05925.1 - 0.028 13.9 0.0 0.51 9.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor G, domain IV PDCD2_C PF04194.8 EDO05926.1 - 8.5e-27 93.7 0.6 4.8e-24 84.7 0.1 2.2 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain YdjO PF14169.1 EDO05926.1 - 0.015 14.7 1.6 5.3 6.5 0.0 3.0 3 0 0 3 3 3 0 Cold-inducible protein YdjO Lar_restr_allev PF14354.1 EDO05926.1 - 0.098 12.9 4.5 1.3 9.3 0.1 3.2 2 1 1 3 3 3 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 EDO05926.1 - 6.1 6.8 8.7 13 5.8 0.0 3.9 4 0 0 4 4 4 0 Zinc ribbon domain Hydrolase_3 PF08282.7 EDO05927.1 - 5.3e-37 127.7 0.0 6.7e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EDO05927.1 - 1.4e-05 24.4 0.0 0.041 13.1 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EDO05927.1 - 0.0078 16.3 0.0 0.15 12.2 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO05927.1 - 0.016 15.6 0.0 0.083 13.2 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2666 PF10869.3 EDO05928.1 - 0.0031 17.5 0.8 0.0064 16.5 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2666) FIVAR PF07554.8 EDO05928.1 - 0.018 15.2 0.8 0.048 13.8 0.6 1.8 1 0 0 1 1 1 0 Uncharacterised Sugar-binding Domain WD40 PF00400.27 EDO05929.1 - 2.9e-27 93.4 0.5 1.2e-07 31.3 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Ricin_B_lectin PF00652.17 EDO05929.1 - 0.018 15.0 1.2 0.29 11.1 0.1 2.3 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain PQQ_2 PF13360.1 EDO05929.1 - 0.03 13.7 0.0 0.1 12.0 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain DUF1258 PF06869.7 EDO05929.1 - 0.085 11.9 0.2 0.17 10.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1258) Aminotran_5 PF00266.14 EDO05931.1 - 2e-112 375.5 0.4 5.7e-112 374.1 0.2 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EDO05931.1 - 3.8e-10 39.2 0.3 6e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EDO05931.1 - 1.1e-06 28.0 0.3 1.7e-06 27.3 0.1 1.4 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EDO05931.1 - 3.3e-05 23.1 0.1 0.00021 20.5 0.0 1.9 1 1 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EDO05931.1 - 0.00013 20.4 0.1 0.00017 19.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme NAD_kinase PF01513.16 EDO05932.1 - 1.4e-09 37.1 0.0 0.00023 20.0 0.0 2.6 3 0 0 3 3 3 2 ATP-NAD kinase DAGK_cat PF00781.19 EDO05932.1 - 0.00019 20.8 0.0 0.00072 18.9 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Glyco_trans_4_3 PF12000.3 EDO05932.1 - 0.037 13.6 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 Gkycosyl transferase family 4 group Cullin_Nedd8 PF10557.4 EDO05932.1 - 0.076 12.8 0.4 0.77 9.6 0.1 2.4 2 0 0 2 2 2 0 Cullin protein neddylation domain EF1_GNE PF00736.14 EDO05933.1 - 3.9e-30 103.3 2.1 9.2e-30 102.1 1.5 1.6 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EDO05933.1 - 0.00046 20.2 2.2 0.00046 20.2 1.5 3.2 2 1 1 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EDO05933.1 - 0.0075 16.7 0.3 0.028 14.8 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GDH_N PF12466.3 EDO05933.1 - 0.043 13.8 0.6 1.2 9.1 0.5 2.3 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal PBP1_TM PF14812.1 EDO05933.1 - 0.069 13.4 8.1 0.87 9.9 0.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GST_C_2 PF13410.1 EDO05933.1 - 0.079 12.8 0.3 0.63 9.9 0.2 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Kinesin PF00225.18 EDO05934.1 - 1.5e-85 286.8 0.3 2.1e-85 286.4 0.2 1.1 1 0 0 1 1 1 1 Kinesin motor domain TFIIA PF03153.8 EDO05935.1 - 6.4e-07 29.6 0.1 8.6e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit P2 PF07194.6 EDO05935.1 - 2 8.3 4.7 0.39 10.6 0.5 1.8 2 0 0 2 2 2 0 P2 response regulator binding domain Pro_isomerase PF00160.16 EDO05936.1 - 3.2e-40 137.8 0.0 4.2e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Mito_carr PF00153.22 EDO05937.1 - 2.9e-40 135.8 3.8 1.1e-21 76.3 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein ArsB PF02040.10 EDO05937.1 - 0.031 13.2 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Arsenical pump membrane protein ATP_bind_1 PF03029.12 EDO05938.1 - 4.8e-57 193.2 0.1 6.1e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EDO05938.1 - 2.7e-06 26.9 0.1 5.4e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EDO05938.1 - 4.3e-05 22.4 0.1 0.00011 21.0 0.0 1.6 3 0 0 3 3 2 1 ArgK protein AAA_16 PF13191.1 EDO05938.1 - 0.0002 21.3 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EDO05938.1 - 0.00021 21.0 0.1 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EDO05938.1 - 0.00031 20.2 0.0 0.00054 19.4 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EDO05938.1 - 0.00037 20.1 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EDO05938.1 - 0.00044 19.2 0.0 0.00064 18.6 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EDO05938.1 - 0.0011 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EDO05938.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDO05938.1 - 0.0017 17.8 0.0 0.015 14.7 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NACHT PF05729.7 EDO05938.1 - 0.0024 17.5 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Pox_A32 PF04665.7 EDO05938.1 - 0.0029 16.9 0.0 0.0073 15.6 0.0 1.7 1 0 0 1 1 1 1 Poxvirus A32 protein NTPase_1 PF03266.10 EDO05938.1 - 0.0033 17.1 0.2 0.014 15.0 0.2 1.9 1 1 0 1 1 1 1 NTPase MipZ PF09140.6 EDO05938.1 - 0.0035 16.4 0.0 0.012 14.7 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ KTI12 PF08433.5 EDO05938.1 - 0.0045 16.2 0.0 0.007 15.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Arch_ATPase PF01637.13 EDO05938.1 - 0.0051 16.5 0.0 0.007 16.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EDO05938.1 - 0.0056 16.5 0.1 0.0096 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EDO05938.1 - 0.0081 15.6 0.3 0.064 12.7 0.1 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Septin PF00735.13 EDO05938.1 - 0.014 14.4 0.0 0.51 9.2 0.0 2.1 2 0 0 2 2 2 0 Septin Gemini_BL1 PF00845.14 EDO05938.1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Geminivirus BL1 movement protein AAA_10 PF12846.2 EDO05938.1 - 0.019 14.4 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 EDO05938.1 - 0.019 15.8 0.5 0.041 14.7 0.2 1.7 2 1 0 2 2 1 0 AAA domain LpxK PF02606.9 EDO05938.1 - 0.027 13.4 0.1 0.04 12.8 0.1 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase AAA_33 PF13671.1 EDO05938.1 - 0.035 13.9 0.0 0.074 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EDO05938.1 - 0.042 13.3 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Flavoprotein PF02441.14 EDO05938.1 - 0.042 13.5 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Flavoprotein UPF0079 PF02367.12 EDO05938.1 - 0.048 13.2 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 EDO05938.1 - 0.052 12.1 0.0 0.091 11.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.8 EDO05938.1 - 0.056 12.3 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EDO05938.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PduV-EutP PF10662.4 EDO05938.1 - 0.063 12.7 0.1 0.56 9.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Thymidylate_kin PF02223.12 EDO05938.1 - 0.069 12.5 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase NB-ARC PF00931.17 EDO05938.1 - 0.071 11.9 0.2 0.24 10.1 0.1 1.8 1 1 1 2 2 2 0 NB-ARC domain DUF87 PF01935.12 EDO05938.1 - 0.073 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF463 PF04317.7 EDO05938.1 - 0.099 11.1 0.0 0.21 10.1 0.0 1.4 1 1 0 1 1 1 0 YcjX-like family, DUF463 ArsA_ATPase PF02374.10 EDO05938.1 - 0.11 11.5 0.1 0.33 9.9 0.0 1.7 1 1 1 2 2 2 0 Anion-transporting ATPase AAA PF00004.24 EDO05938.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GAF PF01590.21 EDO05939.1 - 4.1e-16 59.4 0.2 4.2e-13 49.7 0.1 2.6 2 1 0 2 2 2 2 GAF domain GAF_2 PF13185.1 EDO05939.1 - 5.1e-13 49.7 0.0 7.8e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 EDO05939.1 - 3.3e-10 40.1 0.0 3e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 GAF domain Patatin PF01734.17 EDO05940.1 - 0.0082 16.0 0.5 0.26 11.1 0.0 2.5 1 1 0 2 2 2 2 Patatin-like phospholipase CPSF_A PF03178.10 EDO05941.1 - 9.4e-19 67.6 0.2 5.7e-13 48.6 0.0 3.2 4 0 0 4 4 4 2 CPSF A subunit region DUF1869 PF08956.5 EDO05941.1 - 0.014 14.9 0.3 0.3 10.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) SICA_beta PF12878.2 EDO05941.1 - 0.086 12.6 2.8 0.52 10.0 0.0 2.6 2 0 0 2 2 2 0 SICA extracellular beta domain eRF1_2 PF03464.10 EDO05942.1 - 3.4e-45 153.6 0.0 5.8e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EDO05942.1 - 2.3e-35 121.2 0.4 4.8e-35 120.2 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EDO05942.1 - 1.3e-25 89.5 0.0 2.3e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 DUF1317 PF07026.6 EDO05943.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) HSP70 PF00012.15 EDO05945.1 - 5.4e-268 889.9 7.8 6.1e-268 889.7 5.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO05945.1 - 6.3e-17 61.1 4.4 1.7e-15 56.4 0.6 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EDO05945.1 - 0.0027 17.3 0.0 0.0072 15.9 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EDO05945.1 - 0.011 15.5 4.3 1.8 8.3 0.0 3.9 3 1 0 3 3 3 0 Cell division protein FtsA PADR1 PF08063.7 EDO05945.1 - 0.019 14.3 0.2 0.034 13.5 0.2 1.4 1 0 0 1 1 1 0 PADR1 (NUC008) domain BcrAD_BadFG PF01869.15 EDO05945.1 - 0.044 13.0 1.3 6.2 6.0 0.0 2.6 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family ATP-synt_B PF00430.13 EDO05945.1 - 0.048 13.4 6.8 0.12 12.1 4.7 1.7 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF1947 PF09183.5 EDO05945.1 - 0.23 11.2 0.9 1 9.1 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1947) Ribosomal_S14 PF00253.16 EDO05947.1 - 9.8e-05 21.6 3.3 0.00022 20.5 0.4 2.3 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e DUF2347 PF09804.4 EDO05948.1 - 0.02 14.1 0.5 0.035 13.3 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) EF-hand_9 PF14658.1 EDO05948.1 - 0.027 14.3 0.0 0.75 9.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Ribosomal_S5 PF00333.15 EDO05950.1 - 5.1e-25 86.9 0.5 1e-24 86.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EDO05950.1 - 1.3e-18 66.0 0.0 2.5e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF3389 PF11869.3 EDO05951.1 - 0.0032 17.3 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3389) Glu_cyclase_2 PF05096.7 EDO05952.1 - 4.4e-22 78.3 0.1 7.5e-22 77.6 0.1 1.3 1 1 0 1 1 1 1 Glutamine cyclotransferase zf-DHHC PF01529.15 EDO05953.1 - 2.9e-18 65.8 25.9 2.9e-18 65.8 18.0 3.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase ORC5_C PF14630.1 EDO05955.1 - 2.5e-05 23.8 0.0 0.00011 21.7 0.0 1.9 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus Ribosomal_L12 PF00542.14 EDO05956.1 - 6.8e-22 77.2 1.3 6.4e-20 70.9 0.6 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain TF_Zn_Ribbon PF08271.7 EDO05958.1 - 0.055 12.8 0.9 0.17 11.2 0.6 1.9 1 0 0 1 1 1 0 TFIIB zinc-binding DZR PF12773.2 EDO05958.1 - 0.22 11.3 0.8 0.47 10.3 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon E1-E2_ATPase PF00122.15 EDO05959.1 - 5.9e-18 64.7 0.4 4.8e-17 61.7 0.0 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EDO05959.1 - 1.3e-17 64.9 0.1 2.2e-16 60.9 0.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDO05959.1 - 5.1e-13 49.6 0.5 1.5e-12 48.0 0.3 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDO05959.1 - 1.9e-08 34.1 0.1 4.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDO05959.1 - 0.00081 19.0 0.1 0.0027 17.3 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EDO05959.1 - 0.026 14.7 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DNA_topoisoIV PF00521.15 EDO05960.1 - 2.5e-118 395.6 0.0 4.1e-118 394.9 0.0 1.4 1 1 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.8 EDO05960.1 - 0.0018 17.5 0.2 13 5.2 0.0 4.6 4 1 0 4 4 4 2 DNA gyrase C-terminal domain, beta-propeller HTH_31 PF13560.1 EDO05960.1 - 0.063 13.4 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.17 EDO05960.1 - 0.083 12.7 0.2 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix YajC PF02699.10 EDO05961.1 - 0.0058 16.2 0.0 69 3.2 0.0 4.3 4 0 0 4 4 4 2 Preprotein translocase subunit Big_3_3 PF13750.1 EDO05963.1 - 0.13 11.6 0.0 0.34 10.3 0.0 1.6 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 3) VESA1_N PF12785.2 EDO05964.1 - 2.6e-10 39.8 10.6 6.9e-09 35.1 4.4 2.1 1 1 1 2 2 2 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05965.1 - 1.3e-216 719.9 19.0 1.3e-216 719.9 13.1 2.1 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 YPEB PF14620.1 EDO05965.1 - 0.0066 15.5 0.4 0.01 14.8 0.3 1.2 1 0 0 1 1 1 1 YpeB sporulation ALIX_LYPXL_bnd PF13949.1 EDO05965.1 - 0.0069 15.3 0.4 0.012 14.6 0.3 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Baculo_PEP_C PF04513.7 EDO05965.1 - 0.018 14.8 1.1 0.072 12.9 0.5 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1759 PF03564.10 EDO05965.1 - 0.15 11.8 1.8 14 5.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) ApoLp-III PF07464.6 EDO05965.1 - 0.22 11.5 7.6 0.52 10.3 5.2 1.6 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF3584 PF12128.3 EDO05965.1 - 0.25 8.6 2.7 0.35 8.1 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 EDO05965.1 - 0.42 9.2 5.2 0.67 8.5 1.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein PspA_IM30 PF04012.7 EDO05965.1 - 0.76 9.0 4.3 1.4 8.1 3.0 1.4 1 0 0 1 1 1 0 PspA/IM30 family DUF4175 PF13779.1 EDO05965.1 - 1.1 6.8 0.7 1.6 6.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) F-box-like_2 PF13013.1 EDO05967.1 - 1.2e-14 53.9 2.1 2.2e-13 49.8 0.3 2.4 1 1 2 3 3 3 2 F-box-like domain DUF3420 PF11900.3 EDO05967.1 - 0.077 13.1 0.4 7.8 6.6 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3420) DUF1689 PF07954.6 EDO05968.1 - 0.4 10.5 2.1 1.1 9.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) DUF1469 PF07332.6 EDO05969.1 - 0.00064 19.4 1.9 0.00064 19.4 1.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1469) ETRAMP PF09716.5 EDO05969.1 - 0.013 15.4 1.8 0.019 14.9 0.2 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) UPF0104 PF03706.8 EDO05969.1 - 0.014 14.6 1.9 0.014 14.6 1.3 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0104) RseC_MucC PF04246.7 EDO05969.1 - 0.14 11.7 0.6 0.2 11.1 0.4 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF4203 PF13886.1 EDO05969.1 - 0.15 11.5 8.2 0.22 10.9 5.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4203) Na_H_Exchanger PF00999.16 EDO05969.1 - 0.18 10.2 6.4 0.3 9.5 3.4 1.9 1 1 1 2 2 2 0 Sodium/hydrogen exchanger family DUF3382 PF11862.3 EDO05969.1 - 0.28 11.1 2.6 0.55 10.1 1.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) Cytochrom_B_N PF00033.14 EDO05969.1 - 0.94 8.8 4.5 0.41 9.9 1.7 1.4 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Flavi_NS2B PF01002.14 EDO05969.1 - 1.2 8.6 7.4 6.8 6.3 0.0 2.4 2 1 1 3 3 3 0 Flavivirus non-structural protein NS2B DUF1279 PF06916.8 EDO05970.1 - 0.23 11.7 3.9 3.7 7.9 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) CoA_binding_3 PF13727.1 EDO05970.1 - 0.36 10.6 5.8 0.11 12.3 0.4 2.2 2 0 0 2 2 2 0 CoA-binding domain VESA1_N PF12785.2 EDO05971.1 - 1.1e-21 77.3 10.4 1.1e-21 77.3 7.2 3.9 3 1 1 4 4 4 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05972.1 - 9e-226 750.2 14.2 9e-226 750.2 9.9 2.3 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 Baculo_PEP_C PF04513.7 EDO05972.1 - 0.025 14.4 6.4 4.4 7.1 0.1 4.6 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med11 PF10280.4 EDO05972.1 - 0.097 12.7 0.1 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Mediator complex protein Latarcin PF10279.4 EDO05972.1 - 0.21 11.7 1.2 5.3 7.3 0.9 2.8 1 1 0 1 1 1 0 Latarcin precursor DUF4239 PF14023.1 EDO05973.1 - 0.012 15.0 0.2 0.012 15.0 0.1 4.9 4 2 2 6 6 6 0 Protein of unknown function (DUF4239) DUF1129 PF06570.6 EDO05973.1 - 0.66 9.2 24.8 0.055 12.7 1.5 4.1 3 2 1 4 4 4 0 Protein of unknown function (DUF1129) DUF2231 PF09990.4 EDO05973.1 - 1.3 9.4 13.3 0.57 10.5 0.2 4.1 2 2 0 3 3 3 0 Predicted membrane protein (DUF2231) Mito_carr PF00153.22 EDO05975.1 - 2e-44 149.2 3.1 6.5e-22 77.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Intein_splicing PF14890.1 EDO05977.1 - 0.12 11.1 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Intein splicing domain Peptidase_C1 PF00112.18 EDO05978.1 - 7.4e-27 94.6 12.3 8.1e-26 91.2 7.3 3.0 2 1 0 2 2 2 1 Papain family cysteine protease CathepsinC_exc PF08773.6 EDO05978.1 - 8.7e-07 29.1 0.0 5.6e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.10 EDO05978.1 - 0.25 9.8 1.7 0.25 9.8 0.4 1.4 2 0 0 2 2 2 0 Peptidase C1-like family AAA PF00004.24 EDO05980.1 - 1.1e-43 148.6 0.0 2.2e-43 147.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 EDO05980.1 - 2.5e-12 46.4 1.3 2.5e-12 46.4 0.9 1.7 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 EDO05980.1 - 2.4e-06 27.7 0.0 0.0007 19.7 0.0 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDO05980.1 - 2.6e-06 26.6 0.0 5.8e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EDO05980.1 - 3.9e-06 26.9 0.6 8.3e-05 22.6 0.1 3.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EDO05980.1 - 4.3e-06 27.5 0.1 1.6e-05 25.7 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EDO05980.1 - 1.2e-05 25.0 0.0 5.7e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EDO05980.1 - 1.7e-05 24.6 0.0 3.7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EDO05980.1 - 1.9e-05 24.6 0.0 3.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EDO05980.1 - 1.9e-05 24.1 0.2 0.1 11.9 0.1 2.8 2 1 1 3 3 3 2 AAA domain TIP49 PF06068.8 EDO05980.1 - 2.6e-05 23.1 0.0 6.7e-05 21.7 0.0 1.4 1 1 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EDO05980.1 - 0.00029 20.7 0.0 0.001 18.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EDO05980.1 - 0.00042 19.7 0.0 0.00082 18.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EDO05980.1 - 0.0019 17.9 0.0 0.0055 16.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 EDO05980.1 - 0.0026 17.3 0.2 0.0098 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EDO05980.1 - 0.0036 16.2 0.0 0.006 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EDO05980.1 - 0.0041 17.2 0.0 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 RNA helicase PhoH PF02562.11 EDO05980.1 - 0.0083 15.3 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_18 PF13238.1 EDO05980.1 - 0.0095 16.2 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EDO05980.1 - 0.0095 15.6 0.0 0.39 10.3 0.0 2.4 1 1 1 2 2 2 1 Archaeal ATPase Zeta_toxin PF06414.7 EDO05980.1 - 0.013 14.5 0.0 0.032 13.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 EDO05980.1 - 0.016 14.3 0.0 0.41 9.7 0.0 2.3 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.16 EDO05980.1 - 0.02 14.0 0.0 0.044 12.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ResIII PF04851.10 EDO05980.1 - 0.032 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.7 EDO05980.1 - 0.034 13.8 0.1 0.38 10.3 0.0 2.4 2 1 1 3 3 2 0 NACHT domain Bac_DnaA PF00308.13 EDO05980.1 - 0.038 13.6 0.0 0.22 11.1 0.0 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_3 PF07726.6 EDO05980.1 - 0.04 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EDO05980.1 - 0.048 12.5 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EDO05980.1 - 0.081 12.3 0.0 0.28 10.6 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 EDO05980.1 - 0.12 11.2 0.2 6.2 5.7 0.0 2.5 2 1 1 3 3 3 0 KAP family P-loop domain UPF0079 PF02367.12 EDO05980.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Viral_Hsp90 PF03225.9 EDO05980.1 - 0.16 10.2 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Pro_isomerase PF00160.16 EDO05981.1 - 1.3e-49 168.4 0.0 1.5e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EDO05982.1 - 3.6e-10 39.3 0.3 0.004 16.9 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat STT3 PF02516.9 EDO05983.1 - 6.9e-59 200.0 33.4 1.3e-58 199.1 23.2 1.3 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DUF676 PF05057.9 EDO05984.1 - 2.7e-15 56.2 0.0 3.5e-14 52.6 0.0 2.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EDO05984.1 - 0.041 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EDO05984.1 - 0.14 11.7 0.1 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein PGI PF00342.14 EDO05985.1 - 2e-161 537.7 0.0 2.5e-161 537.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase CBF PF03914.12 EDO05987.1 - 6.1e-10 38.7 1.4 1.4e-09 37.5 1.0 1.6 1 0 0 1 1 1 1 CBF/Mak21 family MMR_HSR1 PF01926.18 EDO05988.1 - 7.7e-10 38.7 0.0 4.6e-09 36.2 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase NOG1 PF06858.9 EDO05988.1 - 1.5e-09 37.6 0.0 1.3e-08 34.5 0.0 2.6 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) AAA_14 PF13173.1 EDO05988.1 - 3.7e-05 23.6 0.6 0.026 14.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain FeoB_N PF02421.13 EDO05988.1 - 0.019 14.2 0.1 0.1 11.9 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B COG4 PF08318.7 EDO05989.1 - 2.7e-09 36.2 0.2 2.7e-09 36.2 0.1 2.6 3 0 0 3 3 3 1 COG4 transport protein MBOAT_2 PF13813.1 EDO05989.1 - 0.39 10.8 1.7 23 5.1 0.2 3.3 3 0 0 3 3 3 0 Membrane bound O-acyl transferase family RabGAP-TBC PF00566.13 EDO05991.1 - 3.8e-53 180.1 8.0 4.3e-53 179.9 5.5 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CPSase_L_D3 PF02787.14 EDO05991.1 - 0.094 12.4 0.2 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain SUV3_C PF12513.3 EDO05991.1 - 0.25 10.8 2.3 0.52 9.7 0.8 2.2 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal Glyco_transf_20 PF00982.16 EDO05992.1 - 4.8e-101 338.5 0.0 6e-101 338.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EDO05992.1 - 2e-37 128.3 0.0 4.6e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase CBM_20 PF00686.14 EDO05992.1 - 1e-12 47.4 0.0 2.4e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain TPR_9 PF13371.1 EDO05992.1 - 0.092 12.6 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Hydrolase_3 PF08282.7 EDO05992.1 - 0.24 10.9 0.0 0.44 10.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NTP_transferase PF00483.18 EDO05994.1 - 2e-13 50.2 0.1 8.8e-13 48.1 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EDO05994.1 - 4.4e-05 23.6 0.0 6.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EDO05994.1 - 0.0032 17.0 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase RRM_1 PF00076.17 EDO05995.1 - 2.7e-11 42.9 0.1 9e-05 22.0 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO05995.1 - 3.2e-10 39.8 0.1 7.3e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO05995.1 - 6.6e-09 35.4 0.0 5.2e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Topoisom_bac PF01131.15 EDO05996.1 - 1.6e-92 310.4 0.0 1.9e-92 310.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EDO05996.1 - 8.1e-13 48.2 0.0 1.9e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Ribosomal_S27e PF01667.12 EDO05996.1 - 0.034 13.6 0.2 0.034 13.6 0.1 2.9 3 0 0 3 3 3 0 Ribosomal protein S27 RNA_pol_N PF01194.12 EDO05996.1 - 0.1 12.6 0.0 0.1 12.6 0.0 2.4 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit VESA1_N PF12785.2 EDO05997.1 - 9.4e-232 769.9 19.0 9.4e-232 769.9 13.2 2.6 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 Baculo_PEP_C PF04513.7 EDO05997.1 - 0.5 10.1 2.4 2.4 7.9 0.0 3.0 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus VESA1_N PF12785.2 EDO05998.1 - 4.9e-23 81.8 9.8 3.7e-12 45.9 0.0 4.7 2 2 2 4 4 4 3 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO05999.1 - 1.4e-201 670.4 22.8 1.4e-201 670.4 15.8 2.7 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 DDE_Tnp_1_assoc PF13808.1 EDO05999.1 - 0.0034 17.0 0.0 0.01 15.5 0.0 1.8 1 0 0 1 1 1 1 DDE_Tnp_1-associated Baculo_PEP_C PF04513.7 EDO05999.1 - 2.8 7.7 6.2 3 7.6 0.2 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.6 EDO05999.1 - 6.3 7.2 5.6 1.7 9.1 0.0 2.7 3 0 0 3 3 3 0 Syntaxin 6, N-terminal F-box-like_2 PF13013.1 EDO06000.1 - 0.00011 21.8 0.1 0.06 13.0 0.0 2.2 2 0 0 2 2 2 2 F-box-like domain DUF3874 PF12990.2 EDO06001.1 - 0.00022 21.2 0.0 0.00066 19.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknonw function from B. Theta Gene description (DUF3874) zf-RING_5 PF14634.1 EDO06002.1 - 2e-08 33.8 6.5 5.1e-08 32.5 4.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDO06002.1 - 2.1e-08 33.7 8.5 9.1e-08 31.6 5.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO06002.1 - 3.3e-08 33.2 5.5 7.6e-08 32.0 3.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDO06002.1 - 9.8e-08 31.9 7.5 6.6e-07 29.2 5.2 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO06002.1 - 1.1e-05 24.9 6.7 2.7e-05 23.7 4.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDO06002.1 - 3.2e-05 23.9 0.8 3.2e-05 23.9 0.6 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger Rtf2 PF04641.7 EDO06002.1 - 0.0052 16.0 0.4 0.0078 15.4 0.3 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EDO06002.1 - 0.011 15.3 4.7 0.038 13.7 2.3 2.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EDO06002.1 - 0.018 14.9 4.6 0.018 14.9 3.2 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EDO06002.1 - 0.13 11.8 10.5 0.84 9.2 7.4 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EDO06002.1 - 0.17 11.4 5.3 0.13 11.7 0.7 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EDO06002.1 - 0.55 10.0 4.2 1 9.2 0.9 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.7 EDO06002.1 - 0.67 9.7 4.6 1 9.1 1.6 2.2 1 1 2 3 3 3 0 zinc-ribbons zf-MIZ PF02891.15 EDO06002.1 - 1.2 8.6 9.0 0.24 10.9 0.8 2.6 3 0 0 3 3 2 0 MIZ/SP-RING zinc finger SURF1 PF02104.10 EDO06003.1 - 1.8e-32 112.8 0.0 3.8e-32 111.8 0.0 1.4 1 1 0 1 1 1 1 SURF1 family RabGAP-TBC PF00566.13 EDO06004.1 - 5.8e-07 29.1 0.1 1.2e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rrf2 PF02082.15 EDO06005.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator zf-C2H2_jaz PF12171.3 EDO06006.1 - 1.2e-05 25.3 2.3 2.7e-05 24.1 1.6 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 EDO06006.1 - 0.00058 19.6 1.1 0.0008 19.2 0.8 1.3 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-met PF12874.2 EDO06006.1 - 0.0028 17.7 1.6 0.0058 16.7 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SPASM PF13186.1 EDO06006.1 - 0.0028 17.9 0.0 0.093 13.0 0.0 2.2 1 1 1 2 2 2 2 Iron-sulfur cluster-binding domain zf-C2H2_2 PF12756.2 EDO06006.1 - 0.0076 16.3 0.7 0.0098 15.9 0.5 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF3505 PF12013.3 EDO06006.1 - 0.01 16.0 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) tRNA_m1G_MT PF01746.16 EDO06007.1 - 2.6e-09 36.9 1.3 2.6e-09 36.9 0.9 2.5 2 1 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Plectin PF00681.15 EDO06007.1 - 0.00042 19.7 0.0 0.00086 18.7 0.0 1.5 1 0 0 1 1 1 1 Plectin repeat Pox_Ag35 PF03286.9 EDO06007.1 - 0.00051 19.6 8.1 0.00053 19.5 5.0 1.4 1 1 0 1 1 1 1 Pox virus Ag35 surface protein SAGA-Tad1 PF12767.2 EDO06007.1 - 0.039 13.6 6.6 0.067 12.8 4.6 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit GST_C PF00043.20 EDO06007.1 - 0.69 9.9 2.6 1.6 8.7 1.8 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EF-hand_8 PF13833.1 EDO06008.1 - 0.00012 21.6 0.1 0.25 11.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 EDO06008.1 - 0.0019 18.3 1.4 0.23 11.6 0.2 2.7 2 1 1 3 3 3 1 EF-hand domain pair NADPH_Ox PF08414.5 EDO06008.1 - 0.0081 16.2 0.3 0.038 14.0 0.0 2.0 2 0 0 2 2 2 1 Respiratory burst NADPH oxidase EF-hand_6 PF13405.1 EDO06008.1 - 0.019 14.8 0.4 13 6.0 0.0 4.0 4 0 0 4 4 4 0 EF-hand domain DUF2624 PF11116.3 EDO06008.1 - 0.048 14.1 4.6 0.15 12.6 1.0 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF2624) STAS PF01740.16 EDO06008.1 - 0.061 12.7 0.9 0.23 10.8 0.7 1.8 1 1 0 1 1 1 0 STAS domain NTNH_C PF08470.5 EDO06008.1 - 0.071 12.7 2.7 0.18 11.4 0.9 1.9 1 1 0 2 2 2 0 Nontoxic nonhaemagglutinin C-terminal Lip_prot_lig_C PF10437.4 EDO06008.1 - 0.087 12.5 2.7 0.54 9.9 0.1 3.0 3 1 1 4 4 4 0 Bacterial lipoate protein ligase C-terminus TerB PF05099.8 EDO06008.1 - 0.12 12.1 0.2 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TerB p25-alpha PF05517.7 EDO06008.1 - 0.77 10.0 3.6 14 5.9 0.3 2.2 1 1 1 2 2 2 0 p25-alpha zf-Tim10_DDP PF02953.10 EDO06009.1 - 1.2e-09 37.2 1.0 1.4e-09 37.0 0.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CDtoxinA PF03498.9 EDO06009.1 - 0.011 15.0 0.2 0.012 14.9 0.1 1.1 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family c-SKI_SMAD_bind PF08782.5 EDO06009.1 - 0.014 15.4 0.3 0.019 15.0 0.2 1.2 1 0 0 1 1 1 0 c-SKI Smad4 binding domain XPG_I PF00867.13 EDO06010.1 - 4.9e-26 90.6 0.0 1.4e-25 89.1 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EDO06010.1 - 1.6e-15 57.1 0.0 3.3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EDO06010.1 - 0.00086 18.8 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EDO06010.1 - 0.043 14.0 0.2 0.24 11.6 0.0 2.3 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold TFIIS_C PF01096.13 EDO06011.1 - 1.5e-20 72.5 4.0 1.5e-20 72.5 2.8 3.2 2 1 0 2 2 1 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 EDO06011.1 - 9.2e-05 22.1 9.1 0.0001 22.0 0.6 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 EDO06011.1 - 0.0011 18.7 1.4 0.065 13.0 0.0 3.0 3 1 1 4 4 4 1 PhnA Zinc-Ribbon DZR PF12773.2 EDO06011.1 - 0.011 15.4 9.8 0.049 13.4 0.7 2.4 2 1 0 2 2 2 0 Double zinc ribbon DUF2387 PF09526.5 EDO06011.1 - 0.064 13.1 5.2 0.21 11.5 0.6 2.3 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) TF_Zn_Ribbon PF08271.7 EDO06011.1 - 0.095 12.0 11.6 0.095 12.0 0.9 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding zf-CHY PF05495.7 EDO06011.1 - 0.24 11.5 9.6 0.94 9.6 1.2 2.5 2 1 0 2 2 2 0 CHY zinc finger Cytochrom_c3_2 PF14537.1 EDO06011.1 - 0.25 11.6 5.4 3.1 8.1 3.7 2.1 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 EDO06011.1 - 0.46 10.1 9.6 0.099 12.2 1.2 2.4 2 1 0 2 2 2 0 Cytochrome c7 HNH PF01844.18 EDO06011.1 - 0.67 9.8 0.1 0.67 9.8 0.1 2.8 4 0 0 4 4 3 0 HNH endonuclease Cytochrome_C554 PF13435.1 EDO06011.1 - 0.68 9.9 5.1 0.13 12.3 1.1 1.7 2 0 0 2 2 2 0 Cytochrome c554 and c-prime zf-NADH-PPase PF09297.6 EDO06011.1 - 1.7 8.2 6.2 17 4.9 0.0 3.4 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-RING_3 PF14369.1 EDO06011.1 - 1.9 8.5 10.1 4.1 7.4 0.1 3.9 4 0 0 4 4 4 0 zinc-finger Lar_restr_allev PF14354.1 EDO06011.1 - 2 8.7 8.2 1.1 9.6 0.3 2.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar Baculo_LEF5_C PF11792.3 EDO06011.1 - 2.9 7.3 6.9 0.96 8.8 1.6 2.5 2 1 1 3 3 2 0 Baculoviridae late expression factor 5 C-terminal domain HypA PF01155.14 EDO06011.1 - 4 7.1 6.1 4.5 6.9 2.5 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-DNA_Pol PF08996.5 EDO06011.1 - 6.2 6.1 7.2 0.37 10.1 0.5 1.9 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger Cytochrom_CIII PF02085.11 EDO06011.1 - 7.5 6.7 8.8 16 5.6 4.9 2.4 1 1 1 2 2 2 0 Class III cytochrome C family Kelch_3 PF13415.1 EDO06012.1 - 1e-14 54.1 0.2 3.5e-08 33.3 0.0 3.6 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.1 EDO06012.1 - 1.9e-10 40.3 4.3 0.0083 15.8 0.5 3.9 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EDO06012.1 - 2.1e-09 37.0 2.4 0.05 13.5 0.0 3.3 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 EDO06012.1 - 2.4e-08 33.8 0.1 0.01 15.9 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 EDO06012.1 - 0.00084 18.8 1.7 0.17 11.4 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 EDO06012.1 - 0.11 12.3 0.6 32 4.4 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Ret_tiss PF10044.4 EDO06014.1 - 0.039 14.4 0.2 0.54 10.8 0.0 2.4 2 0 0 2 2 2 0 Retinal tissue protein AdoHcyase_NAD PF00670.16 EDO06014.1 - 0.079 12.7 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Mannosyl_trans PF05007.8 EDO06015.1 - 6.4e-61 206.2 27.1 8.9e-61 205.7 18.8 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EDO06015.1 - 1.2e-07 30.9 28.1 4.1e-07 29.1 19.1 2.2 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EDO06015.1 - 0.0001 21.9 7.9 0.0001 21.9 5.5 2.7 2 2 1 3 3 3 1 Protein of unknown function (DUF2029) Sec8_exocyst PF04048.9 EDO06016.1 - 0.0023 17.6 1.9 0.0084 15.7 1.1 2.2 1 1 0 1 1 1 1 Sec8 exocyst complex component specific domain Snapin_Pallidin PF14712.1 EDO06016.1 - 0.56 10.5 6.6 0.34 11.2 2.2 2.5 2 0 0 2 2 2 0 Snapin/Pallidin RRF PF01765.14 EDO06018.1 - 2.7e-07 30.1 0.6 3.7e-07 29.7 0.4 1.3 1 0 0 1 1 1 1 Ribosome recycling factor zf-UBR PF02207.15 EDO06020.1 - 2.8e-16 59.0 13.3 2.8e-16 59.0 9.2 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Pkinase PF00069.20 EDO06021.1 - 8.4e-71 238.1 0.1 1.5e-70 237.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO06021.1 - 3.8e-36 124.4 0.0 7.5e-36 123.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EDO06021.1 - 4.3e-13 49.3 0.4 1.6e-12 47.5 0.0 2.2 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 EDO06021.1 - 4.1e-11 42.3 0.0 1.6e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like EF-hand_6 PF13405.1 EDO06021.1 - 1.3e-09 37.0 0.7 0.0096 15.7 0.0 4.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EDO06021.1 - 1e-08 33.8 3.6 0.0034 16.5 0.2 4.1 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 EDO06021.1 - 2.9e-06 27.3 4.1 0.00016 21.7 1.4 4.0 3 1 2 5 5 5 3 EF-hand domain pair Kdo PF06293.9 EDO06021.1 - 2.1e-05 23.6 0.1 4.5e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_8 PF13833.1 EDO06021.1 - 2.8e-05 23.6 2.5 0.12 12.0 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair PH_11 PF15413.1 EDO06021.1 - 4.5e-05 23.6 2.2 0.0012 19.0 0.9 3.0 2 0 0 2 2 2 1 Pleckstrin homology domain RIO1 PF01163.17 EDO06021.1 - 0.00055 19.3 0.6 0.0018 17.6 0.4 1.8 1 1 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EDO06021.1 - 0.00074 18.9 0.0 0.0078 15.5 0.0 2.2 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 EDO06021.1 - 0.0036 16.1 0.4 0.0066 15.2 0.3 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EDO06021.1 - 0.015 15.0 0.0 4.8 6.8 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family EF-hand_5 PF13202.1 EDO06021.1 - 0.038 13.3 1.2 1.2 8.6 0.0 2.9 2 0 0 2 2 2 0 EF hand LRR_8 PF13855.1 EDO06022.1 - 1.3e-07 31.2 9.8 1.6e-05 24.5 2.1 3.8 3 2 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 EDO06022.1 - 5.1e-07 29.1 8.3 0.0025 17.4 3.1 4.3 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EDO06022.1 - 6.9e-07 28.4 3.9 1.8 8.8 0.0 5.7 4 1 1 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 EDO06022.1 - 4.9e-06 26.0 9.6 1.6 9.0 0.1 6.7 8 1 0 8 8 8 3 Leucine Rich repeat LRR_7 PF13504.1 EDO06022.1 - 0.079 13.2 6.9 84 4.0 0.2 5.6 6 0 0 6 6 6 0 Leucine rich repeat zf-RING_2 PF13639.1 EDO06023.1 - 5.2e-10 38.9 8.1 1.4e-09 37.6 5.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EDO06023.1 - 1.6e-09 37.2 8.4 4e-09 36.0 5.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EDO06023.1 - 5.9e-09 35.6 9.9 5.9e-09 35.6 6.9 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EDO06023.1 - 3.6e-08 32.9 6.1 6.7e-08 32.0 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO06023.1 - 1.7e-07 30.7 8.6 4.2e-07 29.5 6.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO06023.1 - 1.7e-07 31.1 8.9 1.7e-07 31.1 6.1 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO06023.1 - 5.9e-06 25.9 3.9 1.6e-05 24.5 1.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger U-box PF04564.10 EDO06023.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.1 EDO06023.1 - 0.005 16.3 5.1 0.016 14.7 3.5 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 EDO06023.1 - 0.0073 16.3 3.2 0.0073 16.3 2.2 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EDO06023.1 - 0.029 14.1 3.0 0.069 12.9 2.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EDO06023.1 - 0.4 10.5 4.9 0.21 11.4 1.1 2.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger GTP_EFTU PF00009.22 EDO06024.1 - 3.2e-45 153.9 0.0 3.9e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDO06024.1 - 5.9e-19 68.0 0.6 2.1e-18 66.2 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDO06024.1 - 4.9e-07 29.7 0.2 1.4e-06 28.2 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO06024.1 - 0.0029 17.5 0.0 0.0068 16.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.10 EDO06024.1 - 0.23 11.0 0.1 0.23 11.0 0.1 2.8 3 0 0 3 3 3 0 Ataxin-2 C-terminal region Ribosomal_L37 PF08561.5 EDO06025.1 - 3.7e-12 45.6 0.0 5.2e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 RAP PF08373.5 EDO06026.1 - 5.4e-12 45.3 0.5 5.4e-12 45.3 0.3 2.1 2 0 0 2 2 2 1 RAP domain DUF1411 PF07199.6 EDO06027.1 - 0.011 15.1 0.3 0.011 15.1 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) DUF2281 PF10047.4 EDO06028.1 - 0.14 12.4 5.7 60 4.0 0.0 5.0 4 1 1 5 5 5 0 Protein of unknown function (DUF2281) DUF1411 PF07199.6 EDO06029.1 - 0.012 15.1 0.1 0.022 14.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) CPSF100_C PF13299.1 EDO06029.1 - 0.015 15.5 0.2 0.025 14.7 0.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NPV_P10 PF05531.7 EDO06029.1 - 0.018 15.2 0.1 0.06 13.5 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2267 PF10025.4 EDO06029.1 - 0.11 12.5 1.0 4.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) IncA PF04156.9 EDO06029.1 - 0.14 11.7 1.3 1.3 8.5 0.9 2.0 1 1 0 1 1 1 0 IncA protein Med21 PF11221.3 EDO06029.1 - 3.7 7.5 7.1 11 5.9 0.8 2.8 2 1 0 2 2 2 0 Subunit 21 of Mediator complex DUF4414 PF14377.1 EDO06030.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4414) eIF-3c_N PF05470.7 EDO06030.1 - 0.11 10.6 0.1 0.11 10.5 0.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF1411 PF07199.6 EDO06031.1 - 0.0013 18.2 0.5 0.0039 16.6 0.1 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1411) DUF2281 PF10047.4 EDO06031.1 - 0.15 12.3 2.5 0.93 9.8 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2281) FKBP_N PF01346.13 EDO06031.1 - 0.17 11.9 9.5 0.03 14.3 2.8 2.5 2 1 1 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase IncA PF04156.9 EDO06031.1 - 0.61 9.6 7.1 6.1 6.4 4.2 2.1 2 0 0 2 2 2 0 IncA protein Xpo1 PF08389.7 EDO06031.1 - 1.6 8.5 4.8 2.6 7.9 0.7 2.3 2 1 0 2 2 2 0 Exportin 1-like protein Herpes_LMP1 PF05297.6 EDO06031.1 - 1.8 7.3 6.1 3 6.6 4.2 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Syntaxin_2 PF14523.1 EDO06031.1 - 4.9 7.2 7.2 40 4.3 2.6 2.8 2 1 0 2 2 2 0 Syntaxin-like protein DUF4414 PF14377.1 EDO06031.1 - 4.9 7.1 7.4 43 4.0 3.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4414) SMN PF06003.7 EDO06031.1 - 6.8 5.7 11.7 2.6 7.0 6.2 1.7 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) DUF1510 PF07423.6 EDO06033.1 - 0.0061 15.9 2.5 0.0072 15.7 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF1411 PF07199.6 EDO06033.1 - 0.11 11.9 2.6 0.12 11.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1411) Myb_DNA-binding PF00249.26 EDO06035.1 - 4.1e-11 42.7 0.0 0.00016 21.6 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO06035.1 - 0.00072 19.6 4.8 0.011 15.8 0.8 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Pkinase PF00069.20 EDO06036.1 - 7.9e-30 103.8 0.0 1.7e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO06036.1 - 1.9e-24 86.1 0.0 4.1e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO06036.1 - 0.0067 15.4 0.0 0.016 14.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like CesA PF11439.3 EDO06036.1 - 0.054 13.4 0.6 0.19 11.6 0.4 1.9 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA DUF4131 PF13567.1 EDO06037.1 - 0.042 13.2 0.0 0.22 10.8 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) TM_helix PF05552.7 EDO06037.1 - 0.048 13.3 0.2 0.089 12.4 0.1 1.4 1 0 0 1 1 1 0 Conserved TM helix Thymidylat_synt PF00303.14 EDO06038.1 - 8.1e-114 379.1 0.0 1e-113 378.8 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.14 EDO06038.1 - 3.8e-31 107.8 0.0 2e-30 105.4 0.0 1.9 1 1 0 1 1 1 1 Dihydrofolate reductase MreB_Mbl PF06723.8 EDO06038.1 - 0.068 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein RibD_C PF01872.12 EDO06038.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 RibD C-terminal domain Porin_O_P PF07396.6 EDO06038.1 - 0.097 11.5 0.0 0.21 10.4 0.0 1.4 1 1 0 1 1 1 0 Phosphate-selective porin O and P AMP-binding PF00501.23 EDO06040.1 - 2.7e-06 26.0 0.0 0.001 17.5 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme DEAD PF00270.24 EDO06041.1 - 3.3e-18 65.7 0.0 1.8e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO06041.1 - 1e-16 60.5 0.0 3.6e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 EDO06041.1 - 5.8e-16 58.1 0.0 1.2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 RQC domain ResIII PF04851.10 EDO06041.1 - 6.4e-05 22.8 0.0 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SMC_N PF02463.14 EDO06042.1 - 4e-14 52.3 10.6 2.6e-06 26.8 5.4 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDO06042.1 - 4.6e-06 26.7 3.2 0.0061 16.5 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EDO06042.1 - 4.9e-06 27.0 6.7 4.9e-06 27.0 4.6 3.6 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EDO06042.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain CDC45 PF02724.9 EDO06043.1 - 0.0023 16.0 8.2 0.0029 15.7 5.7 1.2 1 0 0 1 1 1 1 CDC45-like protein Daxx PF03344.10 EDO06043.1 - 0.029 12.8 15.4 0.038 12.4 10.7 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EDO06043.1 - 0.091 12.0 18.8 0.13 11.5 13.1 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EDO06043.1 - 0.19 9.6 19.8 0.27 9.1 13.7 1.1 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.17 EDO06043.1 - 2 7.3 4.7 2.7 6.9 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 EDO06043.1 - 2.7 7.3 17.8 4 6.7 12.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2457 PF10446.4 EDO06043.1 - 3.2 6.3 24.3 4.6 5.8 16.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Kri1_C PF12936.2 EDO06045.1 - 3e-21 75.1 2.1 3e-21 75.1 1.4 3.4 3 0 0 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.7 EDO06045.1 - 1.3e-13 51.0 9.6 1.3e-13 51.0 6.6 3.7 2 2 1 3 3 3 1 KRI1-like family ZZ PF00569.12 EDO06045.1 - 0.35 10.4 6.5 1.2 8.6 4.5 1.9 1 0 0 1 1 1 0 Zinc finger, ZZ type Peptidase_M41 PF01434.13 EDO06047.1 - 4.2e-58 196.3 1.0 6e-58 195.8 0.7 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EDO06047.1 - 7.9e-43 145.8 0.0 2.1e-42 144.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDO06047.1 - 4.4e-06 26.8 0.9 0.00048 20.1 0.1 2.9 3 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 EDO06047.1 - 5e-05 22.1 0.3 0.00013 20.8 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 EDO06047.1 - 6.9e-05 22.0 0.0 0.00015 20.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EDO06047.1 - 0.00016 21.1 0.3 0.2 11.0 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 EDO06047.1 - 0.00022 22.0 0.0 0.00083 20.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO06047.1 - 0.00025 20.7 0.1 0.00063 19.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EDO06047.1 - 0.00027 21.0 1.2 0.015 15.4 0.1 3.4 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EDO06047.1 - 0.0013 18.6 0.1 0.037 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EDO06047.1 - 0.0016 17.9 0.0 0.0035 16.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EDO06047.1 - 0.0017 17.4 0.0 0.0047 16.0 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EDO06047.1 - 0.0039 17.1 0.1 0.011 15.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EDO06047.1 - 0.0051 16.5 0.1 0.021 14.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EDO06047.1 - 0.01 16.1 0.0 0.029 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EDO06047.1 - 0.02 14.0 0.2 0.043 12.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EDO06047.1 - 0.023 14.5 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.7 EDO06047.1 - 0.048 13.3 0.1 0.67 9.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Ribosomal_L6e PF01159.14 EDO06048.1 - 9e-32 109.5 0.2 1.2e-31 109.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L6e NUMOD3 PF07460.6 EDO06048.1 - 0.086 12.7 0.3 0.23 11.3 0.2 1.7 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) KOW PF00467.24 EDO06048.1 - 0.16 11.7 0.6 0.62 9.8 0.0 2.1 2 0 0 2 2 2 0 KOW motif EF1G PF00647.14 EDO06049.1 - 1.1e-35 121.5 1.2 3.1e-35 120.1 0.5 1.9 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EDO06049.1 - 0.0025 17.7 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDO06049.1 - 0.0028 17.5 0.0 0.012 15.4 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDO06049.1 - 0.0045 17.4 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain VESA1_N PF12785.2 EDO06050.1 - 3.8e-221 734.9 22.5 3.8e-221 734.9 15.6 2.7 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 TMP_2 PF06791.8 EDO06050.1 - 0.22 11.1 3.8 0.49 9.9 2.6 1.5 1 0 0 1 1 1 0 Prophage tail length tape measure protein ApoLp-III PF07464.6 EDO06050.1 - 0.54 10.2 20.8 0.038 14.0 1.1 3.5 3 1 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) YPEB PF14620.1 EDO06050.1 - 0.91 8.4 5.6 4.6 6.1 3.9 1.9 1 1 0 1 1 1 0 YpeB sporulation DUF148 PF02520.12 EDO06050.1 - 1.6 8.5 5.7 1.3 8.8 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF724 PF05266.9 EDO06050.1 - 1.8 8.1 6.7 4.2 6.9 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) VESA1_N PF12785.2 EDO06051.1 - 3.4e-17 62.5 10.6 2.2e-10 40.1 0.1 5.4 4 1 1 6 6 6 3 Variant erythrocyte surface antigen-1 MFS_1 PF07690.11 EDO06053.1 - 6.6e-17 61.2 18.3 6.6e-17 61.2 12.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily VESA1_N PF12785.2 EDO06054.1 - 3.8e-39 134.9 0.8 5.8e-39 134.3 0.5 1.2 1 0 0 1 1 1 1 Variant erythrocyte surface antigen-1 SprT-like PF10263.4 EDO06055.1 - 2.6e-29 101.9 1.6 1.5e-28 99.4 1.1 1.8 1 1 0 1 1 1 1 SprT-like family DUF4368 PF14287.1 EDO06055.1 - 0.028 14.2 0.1 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) Peptidase_M76 PF09768.4 EDO06055.1 - 0.045 13.2 0.2 0.093 12.1 0.1 1.4 1 1 0 1 1 1 0 Peptidase M76 family BBIP10 PF14777.1 EDO06056.1 - 0.15 11.4 0.2 0.15 11.4 0.1 2.2 3 0 0 3 3 3 0 Cilia BBSome complex subunit 10 zf-rbx1 PF12678.2 EDO06056.1 - 0.17 11.9 4.4 0.37 10.9 3.0 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 EDO06056.1 - 0.39 10.5 4.7 0.82 9.5 2.9 1.8 2 0 0 2 2 2 0 Ring finger domain WD40 PF00400.27 EDO06060.1 - 1e-36 123.5 48.0 8.7e-11 41.2 0.2 10.9 13 0 0 13 13 13 5 WD domain, G-beta repeat Utp12 PF04003.7 EDO06060.1 - 4.9e-10 39.2 0.0 8.6e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EDO06060.1 - 0.00017 21.3 1.6 0.2 11.3 0.0 5.2 7 0 0 7 7 7 1 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.6 EDO06060.1 - 0.0087 14.9 1.1 4.1 6.2 0.0 4.0 5 0 0 5 5 5 1 Protein of unknown function (DUF1513) CPSF_A PF03178.10 EDO06060.1 - 0.099 11.7 0.0 18 4.3 0.0 3.2 3 0 0 3 3 3 0 CPSF A subunit region OHA PF14418.1 EDO06061.1 - 4.9e-21 74.0 0.0 1e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 OST-HTH Associated domain TPR_11 PF13414.1 EDO06062.1 - 7.1e-06 25.5 10.2 0.00013 21.5 1.7 3.7 3 0 0 3 3 3 2 TPR repeat Arm PF00514.18 EDO06062.1 - 0.0038 16.9 0.3 3.8 7.4 0.1 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat TPR_8 PF13181.1 EDO06062.1 - 0.0092 15.6 2.3 0.089 12.6 0.2 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EDO06062.1 - 0.011 15.8 1.1 0.011 15.8 0.8 3.9 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EDO06062.1 - 0.062 13.9 1.8 27 5.6 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO06062.1 - 0.14 12.0 5.3 0.073 13.0 0.6 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat ABA_GPCR PF12430.3 EDO06063.1 - 1.7e-33 115.3 7.2 1.7e-33 115.3 5.0 2.0 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EDO06063.1 - 0.047 13.7 0.2 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) Ribosomal_S6 PF01250.12 EDO06064.1 - 3.2e-11 42.9 0.0 4.2e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Ribosomal_L44 PF00935.14 EDO06065.1 - 4.5e-33 113.1 14.3 6.2e-33 112.6 9.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 RPA PF10134.4 EDO06066.1 - 0.0084 15.3 0.3 0.016 14.5 0.2 1.4 1 0 0 1 1 1 1 Replication initiator protein A Peptidase_C14 PF00656.17 EDO06067.1 - 1.7e-34 119.6 0.0 2.9e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Caspase domain RHD3 PF05879.7 EDO06068.1 - 2.6e-96 323.2 0.0 3.4e-96 322.8 0.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EDO06068.1 - 0.00041 19.4 0.0 0.00072 18.6 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EDO06068.1 - 0.0038 17.0 0.2 0.01 15.7 0.2 1.7 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EDO06068.1 - 0.029 14.8 0.0 0.078 13.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 EDO06068.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RrnaAD PF00398.15 EDO06069.1 - 5.2e-54 183.0 0.0 6.7e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 EDO06069.1 - 1e-10 41.3 0.0 1.7e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO06069.1 - 2.4e-08 33.9 0.0 3.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO06069.1 - 3.6e-06 27.5 0.0 5.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO06069.1 - 3.7e-05 22.9 0.0 6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EDO06069.1 - 6.6e-05 22.0 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EDO06069.1 - 8.6e-05 22.3 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO06069.1 - 0.00012 22.4 0.0 0.00022 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO06069.1 - 0.0017 18.8 0.0 0.0029 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO06069.1 - 0.0018 18.5 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDO06069.1 - 0.0027 17.2 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.6 EDO06069.1 - 0.024 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.7 EDO06069.1 - 0.033 13.0 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase HCNGP PF07818.8 EDO06069.1 - 0.042 13.8 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 HCNGP-like protein PrmA PF06325.8 EDO06069.1 - 0.06 12.4 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF43 PF01861.11 EDO06069.1 - 0.061 12.3 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 tRNA_U5-meth_tr PF05958.6 EDO06069.1 - 0.16 10.5 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase HEAT PF02985.17 EDO06070.1 - 8.4e-20 69.0 18.9 0.009 16.0 0.0 10.5 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.1 EDO06070.1 - 4.2e-12 46.1 0.2 0.021 15.0 0.0 5.8 3 3 2 5 5 5 4 HEAT repeats Vac14_Fab1_bd PF12755.2 EDO06070.1 - 3.2e-05 24.2 3.0 0.069 13.5 0.0 4.9 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EDO06070.1 - 4.6e-05 22.8 1.5 0.19 11.0 0.0 3.8 3 1 0 3 3 3 2 CLASP N terminal DUF2454 PF10521.4 EDO06070.1 - 0.0016 17.5 0.1 0.063 12.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) Adaptin_N PF01602.15 EDO06070.1 - 0.0023 16.3 7.1 2.1 6.5 0.0 3.3 3 0 0 3 3 3 3 Adaptin N terminal region DUF2435 PF10363.4 EDO06070.1 - 0.031 14.1 0.2 5.1 7.0 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2435) ALAD PF00490.16 EDO06071.1 - 2e-95 319.4 0.0 2.4e-95 319.1 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Peptidase_M16_C PF05193.16 EDO06072.1 - 5.5e-23 81.6 0.6 3.4e-10 39.8 0.0 3.9 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EDO06072.1 - 3.1e-16 59.4 0.1 1.3e-14 54.1 0.0 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) zf-B_box PF00643.19 EDO06073.1 - 1.8e-10 40.5 17.0 1.9e-05 24.4 3.9 2.6 2 0 0 2 2 2 2 B-box zinc finger ALIX_LYPXL_bnd PF13949.1 EDO06073.1 - 0.055 12.4 1.0 0.098 11.6 0.5 1.5 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV RNA_pol_L_2 PF13656.1 EDO06074.1 - 4.6e-28 96.4 0.0 5.3e-28 96.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EDO06074.1 - 4.5e-07 28.8 0.0 5.9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain tRNA-synt_2 PF00152.15 EDO06075.1 - 1.4e-69 234.4 0.0 2e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDO06075.1 - 3.1e-07 30.1 0.1 5.3e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EDO06075.1 - 4.2e-07 29.4 0.0 7.3e-05 22.0 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EDO06075.1 - 0.0007 19.2 0.2 0.0099 15.4 0.1 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Prefoldin_2 PF01920.15 EDO06076.1 - 1.3e-15 57.0 2.6 1.6e-15 56.7 1.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin PF00804.20 EDO06076.1 - 0.0065 16.6 0.7 0.03 14.4 0.0 2.0 2 0 0 2 2 2 1 Syntaxin DUF1978 PF09321.5 EDO06076.1 - 0.037 13.4 1.5 0.89 8.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) Sec8_exocyst PF04048.9 EDO06076.1 - 0.043 13.4 0.9 0.35 10.5 0.2 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Kinetocho_Slk19 PF12709.2 EDO06076.1 - 0.63 10.1 4.1 0.79 9.8 0.1 2.2 2 0 0 2 2 2 0 Central kinetochore-associated bZIP_1 PF00170.16 EDO06076.1 - 5.7 6.9 8.7 16 5.5 0.2 2.2 2 0 0 2 2 2 0 bZIP transcription factor s48_45 PF07422.8 EDO06077.1 - 2e-21 76.1 5.2 4.4e-10 39.6 0.0 4.9 5 0 0 5 5 5 4 Sexual stage antigen s48/45 domain s48_45 PF07422.8 EDO06078.1 - 1.4e-20 73.4 3.1 1e-10 41.6 0.1 4.8 4 0 0 4 4 4 4 Sexual stage antigen s48/45 domain s48_45 PF07422.8 EDO06079.1 - 2.2e-22 79.2 2.6 9.9e-11 41.7 0.1 4.1 4 0 0 4 4 4 3 Sexual stage antigen s48/45 domain RRM_1 PF00076.17 EDO06080.1 - 2.1e-06 27.2 0.0 4.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06080.1 - 0.00027 20.7 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF507 PF04368.8 EDO06080.1 - 0.084 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF507) TIM PF00121.13 EDO06081.1 - 6.9e-79 264.3 0.0 7.7e-79 264.1 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MobB PF03205.9 EDO06082.1 - 1.3e-06 28.1 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Clp1 PF06807.9 EDO06082.1 - 0.031 14.0 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Pre-mRNA cleavage complex II protein Clp1 AAA_16 PF13191.1 EDO06082.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Rad21_Rec8 PF04824.11 EDO06083.1 - 3e-08 32.7 0.0 7.6e-08 31.4 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EDO06083.1 - 0.037 13.6 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 ScpA/B protein Motile_Sperm PF00635.21 EDO06084.1 - 1.4e-23 82.5 0.0 2.4e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Tricorn_C1 PF14684.1 EDO06084.1 - 0.15 11.9 0.0 0.55 10.1 0.0 1.8 2 0 0 2 2 2 0 Tricorn protease C1 domain RNA_pol_Rpb6 PF01192.17 EDO06085.1 - 1e-16 60.4 0.3 1.4e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb6 LNS2 PF08235.8 EDO06086.1 - 2.4e-63 212.4 0.0 3.9e-63 211.7 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EDO06086.1 - 9.6e-24 83.1 0.0 4.2e-18 65.0 0.0 2.4 2 0 0 2 2 2 2 lipin, N-terminal conserved region zf-DHHC PF01529.15 EDO06087.1 - 5.9e-37 126.7 4.9 5.9e-37 126.7 3.4 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.2 EDO06087.1 - 1.3e-36 124.7 0.2 1.7e-16 60.3 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EDO06087.1 - 3.2e-23 80.3 6.8 2e-08 33.5 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EDO06087.1 - 4.6e-22 77.9 2.4 4.6e-09 36.5 0.2 4.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDO06087.1 - 3.7e-19 68.3 3.7 5.9e-05 23.1 0.0 5.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO06087.1 - 2.1e-17 61.4 5.3 0.00028 20.8 0.3 5.4 5 0 0 5 5 5 4 Ankyrin repeat Spc97_Spc98 PF04130.8 EDO06088.1 - 1.3e-55 188.7 19.4 2e-55 188.1 13.4 1.3 1 1 0 1 1 1 1 Spc97 / Spc98 family DUF1944 PF09175.5 EDO06088.1 - 0.058 13.0 0.5 0.25 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1944) 2-oxoacid_dh PF00198.18 EDO06089.1 - 4.6e-64 215.8 0.0 6.9e-64 215.2 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EDO06089.1 - 2.3e-17 62.3 0.3 6.3e-17 60.9 0.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EDO06089.1 - 6.5e-12 44.8 0.8 3.3e-11 42.6 0.1 2.4 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EDO06089.1 - 0.002 17.7 0.0 0.0057 16.2 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD PF00529.15 EDO06089.1 - 0.0049 16.2 0.2 0.013 14.7 0.0 1.8 2 0 0 2 2 2 1 HlyD family secretion protein GCV_H PF01597.14 EDO06089.1 - 0.04 13.6 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein KorB PF08535.5 EDO06089.1 - 0.093 12.8 0.0 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 KorB domain IMCp PF12314.3 EDO06090.1 - 1.2e-26 92.6 95.5 6.8e-20 71.0 30.7 3.8 2 2 2 4 4 4 3 Inner membrane complex protein Cuticle_3 PF11018.3 EDO06090.1 - 0.0065 16.6 1.5 2.8 8.0 0.0 2.6 1 1 2 3 3 3 2 Pupal cuticle protein C1 TLD PF07534.11 EDO06091.1 - 2e-18 66.7 0.2 3.7e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.13 EDO06091.1 - 5.4e-09 35.8 2.8 1.2e-08 34.6 2.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rad51 PF08423.6 EDO06092.1 - 1.3e-12 47.2 0.0 3.7e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EDO06092.1 - 2.1e-10 40.3 0.2 1.6e-09 37.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 EDO06092.1 - 8.4e-06 25.0 0.3 0.00015 20.9 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_22 PF13401.1 EDO06092.1 - 0.00011 22.3 0.0 0.00025 21.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 EDO06092.1 - 0.00014 21.1 0.0 0.0048 16.0 0.0 2.2 2 0 0 2 2 2 1 KaiC CobU PF02283.11 EDO06092.1 - 0.00051 19.4 0.1 0.048 13.0 0.0 2.1 1 1 1 2 2 2 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_19 PF13245.1 EDO06092.1 - 0.0031 17.2 0.0 0.84 9.4 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain SEFIR PF08357.6 EDO06092.1 - 0.0038 17.2 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 SEFIR domain AAA_24 PF13479.1 EDO06092.1 - 0.0046 16.5 0.0 0.011 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EDO06092.1 - 0.04 14.1 0.1 0.76 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EDO06092.1 - 0.08 12.4 0.0 0.25 10.8 0.0 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF2075 PF09848.4 EDO06092.1 - 0.098 11.6 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EDO06092.1 - 0.098 12.3 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EDO06092.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 NACHT domain PhoH PF02562.11 EDO06092.1 - 0.11 11.6 0.1 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Fumble PF03630.9 EDO06093.1 - 8.5e-40 136.6 3.9 1.2e-39 136.2 2.7 1.1 1 0 0 1 1 1 1 Fumble VESA1_N PF12785.2 EDO06095.1 - 4.5e-23 81.9 33.2 9.8e-18 64.3 8.9 4.5 2 1 1 3 3 3 3 Variant erythrocyte surface antigen-1 F-box-like_2 PF13013.1 EDO06096.1 - 1.3e-08 34.4 0.2 9.7e-06 25.2 0.0 2.7 2 1 1 3 3 3 3 F-box-like domain F-box-like_2 PF13013.1 EDO06097.1 - 0.0016 18.1 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 F-box-like domain VESA1_N PF12785.2 EDO06098.1 - 1.7e-205 683.3 26.5 1.7e-205 683.3 18.4 2.2 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 Spc7 PF08317.6 EDO06098.1 - 0.035 12.7 3.7 0.067 11.8 2.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein RPW8 PF05659.6 EDO06098.1 - 0.079 12.4 0.9 0.21 11.1 0.6 1.7 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Baculo_PEP_C PF04513.7 EDO06098.1 - 0.1 12.4 1.6 0.38 10.5 0.1 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF937 PF06078.6 EDO06098.1 - 0.44 10.7 3.3 0.94 9.7 0.6 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF937) TPR_MLP1_2 PF07926.7 EDO06098.1 - 1.9 8.2 7.9 0.84 9.3 3.7 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein VESA1_N PF12785.2 EDO06099.1 - 2.3e-209 696.1 20.2 2.3e-209 696.1 14.0 2.9 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 GTPase_Cys_C PF12631.2 EDO06099.1 - 0.0041 17.4 0.1 0.038 14.4 0.2 2.6 3 0 0 3 3 3 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE HsbA PF12296.3 EDO06099.1 - 0.047 13.5 0.5 3.9 7.3 0.0 3.4 4 0 0 4 4 4 0 Hydrophobic surface binding protein A COG2 PF06148.6 EDO06099.1 - 0.057 13.2 2.5 4.6 7.1 0.0 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 EDO06099.1 - 0.079 12.7 0.5 4.2 7.1 0.2 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EDO06099.1 - 0.095 12.2 6.5 1.4 8.4 2.4 2.4 2 0 0 2 2 2 0 IncA protein HCR PF07111.7 EDO06099.1 - 0.22 9.4 4.1 0.32 8.9 2.8 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) Laminin_II PF06009.7 EDO06099.1 - 0.6 9.8 3.7 13 5.5 0.1 2.3 2 0 0 2 2 2 0 Laminin Domain II FliJ PF02050.11 EDO06099.1 - 5.6 7.0 13.2 12 6.0 3.0 3.1 3 0 0 3 3 3 0 Flagellar FliJ protein Wzy_C PF04932.10 EDO06100.1 - 0.13 12.0 4.9 0.28 10.9 0.1 2.6 2 1 0 2 2 2 0 O-Antigen ligase zf-CCCH PF00642.19 EDO06101.1 - 1.4e-08 34.1 22.0 2.7e-07 30.1 4.2 4.0 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_jaz PF12171.3 EDO06102.1 - 4e-08 33.1 1.4 7.5e-08 32.2 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Wbp11 PF09429.5 EDO06102.1 - 0.007 16.3 1.0 0.007 16.3 0.7 1.8 2 0 0 2 2 2 1 WW domain binding protein 11 zf-C2H2 PF00096.21 EDO06102.1 - 0.0075 16.5 2.1 0.0075 16.5 1.4 1.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EDO06102.1 - 0.019 15.0 2.2 0.029 14.4 1.4 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 EDO06102.1 - 0.019 14.4 2.3 0.043 13.3 1.6 1.6 1 0 0 1 1 1 0 U1 zinc finger Rpr2 PF04032.11 EDO06102.1 - 0.073 12.9 0.5 0.13 12.1 0.4 1.6 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain JAB PF01398.16 EDO06103.1 - 4.2e-15 55.4 0.1 7.2e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EDO06103.1 - 0.026 14.5 0.2 0.053 13.6 0.2 1.5 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function MA3 PF02847.12 EDO06103.1 - 0.048 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 MA3 domain ATP-synt_ab PF00006.20 EDO06106.1 - 1.1e-58 198.2 0.0 1.5e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDO06106.1 - 1.4e-17 64.1 0.1 2.6e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDO06106.1 - 3.6e-10 39.9 1.9 6.4e-10 39.0 1.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EDO06106.1 - 0.0016 18.2 0.4 0.0042 16.9 0.3 1.7 1 0 0 1 1 1 1 HAS barrel domain PCI PF01399.22 EDO06109.1 - 1.1e-19 70.6 0.4 1.3e-18 67.2 0.0 2.5 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 EDO06109.1 - 1.4e-14 54.1 0.3 4.4e-14 52.6 0.2 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal Ste50p-SAM PF09235.5 EDO06109.1 - 0.0094 15.9 0.0 0.26 11.3 0.0 2.8 2 0 0 2 2 2 1 Ste50p, sterile alpha motif PCI_Csn8 PF10075.4 EDO06109.1 - 0.037 13.7 0.0 0.097 12.4 0.0 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 EDO06109.1 - 0.041 13.8 0.8 0.041 13.8 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EDO06109.1 - 0.44 10.2 5.7 3.3 7.4 0.5 3.0 2 1 1 3 3 3 0 TPR repeat TPR_12 PF13424.1 EDO06109.1 - 0.65 9.9 10.7 1.3 9.0 0.7 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF972 PF06156.8 EDO06110.1 - 0.0039 17.5 4.6 5.1 7.4 0.9 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF972) HALZ PF02183.13 EDO06110.1 - 0.02 14.6 16.1 0.73 9.6 0.4 5.1 5 0 0 5 5 5 0 Homeobox associated leucine zipper Fib_alpha PF08702.5 EDO06110.1 - 0.032 14.3 5.2 0.67 10.0 1.0 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family HAUS5 PF14817.1 EDO06110.1 - 0.092 11.2 15.4 1.2 7.6 3.3 3.1 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 5 DivIC PF04977.10 EDO06110.1 - 0.12 11.8 8.4 1.8 8.1 0.0 4.0 3 1 2 5 5 5 0 Septum formation initiator DUF641 PF04859.7 EDO06110.1 - 0.32 10.7 5.3 0.68 9.6 1.0 2.9 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.6 EDO06110.1 - 0.4 10.1 4.6 15 5.0 0.1 3.3 3 1 0 3 3 3 0 Phage minor structural protein GP20 bZIP_1 PF00170.16 EDO06110.1 - 0.47 10.4 12.1 3.5 7.6 0.0 4.4 3 1 1 4 4 4 0 bZIP transcription factor TMF_DNA_bd PF12329.3 EDO06110.1 - 0.66 9.8 12.4 0.4 10.5 0.2 4.0 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding GrpE PF01025.14 EDO06110.1 - 0.8 9.2 3.8 2.1 7.8 0.0 2.8 3 0 0 3 3 3 0 GrpE DUF904 PF06005.7 EDO06110.1 - 1.2 9.4 12.4 8.1 6.8 0.0 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF904) DivIVA PF05103.8 EDO06110.1 - 4.1 7.4 7.7 6.3 6.8 0.1 3.3 3 1 0 3 3 3 0 DivIVA protein DUF4200 PF13863.1 EDO06110.1 - 5.5 6.9 9.4 4.2 7.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Cortex-I_coil PF09304.5 EDO06110.1 - 6 6.9 11.6 0.88 9.6 0.3 3.9 3 1 2 5 5 5 0 Cortexillin I, coiled coil Kinesin-relat_1 PF12711.2 EDO06110.1 - 9.2 6.7 12.7 19 5.7 0.1 3.8 4 0 0 4 4 4 0 Kinesin motor vATP-synt_AC39 PF01992.11 EDO06111.1 - 1.2e-47 162.6 0.0 1.5e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit HEPN PF05168.9 EDO06111.1 - 0.17 11.7 0.6 19 5.2 0.0 3.0 2 1 1 3 3 3 0 HEPN domain PRT_C PF08372.5 EDO06112.1 - 0.0006 19.3 1.9 0.008 15.6 0.0 2.7 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal PH PF00169.24 EDO06112.1 - 0.0016 18.5 0.0 0.0066 16.6 0.0 2.1 1 0 0 1 1 1 1 PH domain Gcw_chp PF09694.5 EDO06112.1 - 0.02 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (Gcw_chp) Pex24p PF06398.6 EDO06112.1 - 0.47 9.1 16.8 0.14 10.8 0.5 3.5 3 0 0 3 3 3 0 Integral peroxisomal membrane peroxin YL1 PF05764.8 EDO06113.1 - 5.5e-36 124.3 24.8 5.5e-36 124.3 17.2 2.1 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 EDO06113.1 - 1.1e-13 50.4 1.4 9.5e-13 47.4 0.3 2.3 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Pga1 PF10333.4 EDO06113.1 - 0.044 13.4 0.2 0.084 12.5 0.1 1.4 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator DivIC PF04977.10 EDO06115.1 - 2.3e-06 26.9 12.2 0.0019 17.6 0.9 3.8 3 1 0 3 3 3 2 Septum formation initiator CENP-F_leu_zip PF10473.4 EDO06115.1 - 3.1e-05 23.8 6.4 3.1e-05 23.8 4.4 3.5 4 0 0 4 4 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 EDO06115.1 - 0.00067 19.9 13.8 0.011 16.1 1.3 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF972) ADIP PF11559.3 EDO06115.1 - 0.012 15.5 6.5 0.012 15.5 4.5 3.7 4 0 0 4 4 3 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.16 EDO06115.1 - 0.024 14.5 17.8 0.054 13.4 0.2 4.3 3 1 2 5 5 5 0 bZIP transcription factor DUF2383 PF09537.5 EDO06115.1 - 0.031 14.5 0.2 0.031 14.5 0.2 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF2383) DUF2205 PF10224.4 EDO06115.1 - 0.079 12.5 13.9 1.3 8.6 4.0 3.4 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) HALZ PF02183.13 EDO06115.1 - 0.094 12.4 9.6 0.12 12.1 1.5 3.9 3 1 1 4 4 4 0 Homeobox associated leucine zipper Occludin_ELL PF07303.8 EDO06115.1 - 0.11 13.2 5.8 9.2 7.0 0.3 3.5 4 0 0 4 4 3 0 Occludin homology domain KLRAQ PF10205.4 EDO06115.1 - 0.2 11.6 15.2 3.1 7.8 3.5 3.6 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein NPV_P10 PF05531.7 EDO06115.1 - 0.21 11.8 14.6 1.4 9.1 0.5 4.5 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3135 PF11333.3 EDO06115.1 - 0.24 11.5 5.1 37 4.5 0.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3135) DUF904 PF06005.7 EDO06115.1 - 0.33 11.2 21.5 0.44 10.8 3.9 4.3 4 2 1 5 5 4 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 EDO06115.1 - 0.35 11.3 13.9 2.9 8.3 0.1 4.0 4 0 0 4 4 3 0 N-terminal domain of unknown function (DUF4140) Reo_sigmaC PF04582.7 EDO06115.1 - 0.4 9.8 13.7 0.15 11.2 3.1 2.6 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Shugoshin_N PF07558.6 EDO06115.1 - 0.46 10.2 7.9 0.3 10.8 1.8 2.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region SlyX PF04102.7 EDO06115.1 - 0.55 10.6 17.5 0.12 12.8 0.8 4.9 4 1 1 5 5 5 0 SlyX Cep57_CLD_2 PF14197.1 EDO06115.1 - 0.67 9.9 19.9 0.57 10.1 0.5 4.5 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 zf-ZPR1 PF03367.8 EDO06115.1 - 0.73 8.9 5.9 4.3 6.4 0.1 3.6 4 1 0 4 4 4 0 ZPR1 zinc-finger domain Lge1 PF11488.3 EDO06115.1 - 0.81 9.9 9.2 1.7 8.8 2.4 3.5 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 DUF4200 PF13863.1 EDO06115.1 - 1.5 8.7 14.3 1.9 8.4 2.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 EDO06115.1 - 2.1 6.1 11.6 1.7 6.4 3.3 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TSC22 PF01166.13 EDO06115.1 - 2.4 8.1 13.8 3.4 7.6 0.1 4.4 3 1 2 5 5 5 0 TSC-22/dip/bun family DUF724 PF05266.9 EDO06115.1 - 3.5 7.1 11.7 0.23 11.0 1.6 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF724) Phage_GP20 PF06810.6 EDO06115.1 - 3.6 7.0 18.5 4.7 6.6 0.1 3.9 4 0 0 4 4 4 0 Phage minor structural protein GP20 Baculo_PEP_C PF04513.7 EDO06115.1 - 4 7.2 18.8 0.12 12.2 2.6 3.2 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EDO06115.1 - 5.5 6.5 27.2 5.3 6.5 0.8 3.1 2 1 1 3 3 3 0 IncA protein DUF641 PF04859.7 EDO06115.1 - 6.1 6.6 12.6 0.69 9.6 0.5 3.9 2 2 1 4 4 4 0 Plant protein of unknown function (DUF641) Nsp1_C PF05064.8 EDO06115.1 - 6.7 6.3 12.5 0.038 13.6 1.6 2.5 3 0 0 3 3 3 0 Nsp1-like C-terminal region Vps5 PF09325.5 EDO06115.1 - 8.3 5.5 13.8 7.3 5.7 2.6 3.2 3 0 0 3 3 3 0 Vps5 C terminal like Fzo_mitofusin PF04799.8 EDO06115.1 - 9.6 5.5 9.5 3.1 7.1 1.1 2.8 3 0 0 3 3 2 0 fzo-like conserved region NOC3p PF07540.6 EDO06116.1 - 0.0025 18.0 0.0 0.012 15.8 0.0 2.3 1 1 0 1 1 1 1 Nucleolar complex-associated protein UPF0113 PF03657.8 EDO06117.1 - 6.9e-11 42.0 0.0 8.9e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 EDO06117.1 - 4.3e-05 23.5 0.0 7.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 pre-rRNA processing and ribosome biogenesis AP2 PF00847.15 EDO06118.1 - 1.8e-12 47.2 0.2 3e-12 46.5 0.2 1.4 1 0 0 1 1 1 1 AP2 domain BING4CT PF08149.6 EDO06118.1 - 0.08 12.4 0.0 0.66 9.5 0.0 2.2 2 0 0 2 2 2 0 BING4CT (NUC141) domain PC_rep PF01851.17 EDO06119.1 - 1.2e-30 103.9 17.2 0.00029 20.9 0.1 10.1 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EDO06119.1 - 8.8e-15 54.7 8.2 5.4e-10 39.4 0.1 5.3 3 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EDO06119.1 - 4.5e-06 26.2 1.9 0.52 10.5 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EDO06119.1 - 0.00095 19.5 8.6 0.021 15.2 0.1 5.1 4 1 2 6 6 6 3 HEAT-like repeat HEAT_PBS PF03130.11 EDO06119.1 - 0.059 13.8 3.4 6.8 7.4 0.1 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat RNase_H_2 PF13482.1 EDO06119.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 RNase_H superfamily Kelch_5 PF13854.1 EDO06120.1 - 2.5e-39 132.6 3.7 2.3e-06 27.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Metallophos PF00149.23 EDO06120.1 - 5.2e-35 120.6 0.6 8.6e-35 119.9 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_4 PF13418.1 EDO06120.1 - 2.7e-33 113.5 9.1 1.5e-08 34.2 0.2 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EDO06120.1 - 1.2e-29 101.7 18.0 4.4e-06 26.7 0.2 7.9 9 0 0 9 9 9 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EDO06120.1 - 4.5e-24 83.5 8.7 0.0021 18.1 0.0 6.6 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EDO06120.1 - 1.7e-23 81.3 6.6 0.00016 21.2 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EDO06120.1 - 2.5e-20 71.7 1.4 6.2e-05 22.4 0.0 6.5 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.9 EDO06120.1 - 1.3e-05 24.1 0.4 0.59 8.7 0.1 4.0 5 0 0 5 5 5 2 Recombination activating protein 2 Ribosomal_S3_C PF00189.15 EDO06122.1 - 4e-17 62.2 0.2 1.2e-16 60.6 0.5 1.5 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EDO06122.1 - 3.7e-09 36.0 0.1 5.9e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EDO06122.1 - 0.046 14.0 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 DUF2427 PF10348.4 EDO06123.1 - 0.11 12.1 0.2 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) BK_channel_a PF03493.13 EDO06124.1 - 3.4e-25 87.9 0.1 2.6e-23 81.8 0.0 2.6 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 EDO06124.1 - 1.5e-11 43.8 1.9 1.5e-11 43.8 1.3 1.9 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.26 EDO06124.1 - 0.007 15.6 2.3 0.015 14.5 1.6 1.5 1 0 0 1 1 1 1 Ion transport protein TrkA_C PF02080.16 EDO06124.1 - 0.022 14.3 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-C domain Med4 PF10018.4 EDO06125.1 - 5e-06 26.0 0.1 7.6e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 TBPIP PF07106.8 EDO06126.1 - 0.23 11.0 2.3 1.3 8.5 1.3 2.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CCDC-167 PF15188.1 EDO06126.1 - 0.78 9.7 7.5 0.4 10.6 1.1 3.0 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 COX6A PF02046.10 EDO06127.1 - 0.035 14.0 0.2 0.058 13.3 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa PFU PF09070.6 EDO06128.1 - 0.043 13.8 0.1 0.083 12.9 0.1 1.4 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) PP2C PF00481.16 EDO06129.1 - 1.7e-35 122.6 0.0 2e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EDO06129.1 - 2.1e-05 24.0 0.0 5.2e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SMC_N PF02463.14 EDO06130.1 - 5.4e-65 218.6 0.0 3.8e-64 215.9 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDO06130.1 - 1.5e-16 60.4 0.1 6.2e-16 58.4 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EDO06130.1 - 1.4e-13 51.4 2.1 2.2e-06 27.8 0.5 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EDO06130.1 - 3.7e-10 40.4 3.0 3.7e-10 40.4 2.1 5.5 2 2 0 2 2 1 1 AAA domain Reo_sigmaC PF04582.7 EDO06130.1 - 0.0065 15.6 34.8 0.022 13.9 1.2 5.6 3 2 2 6 6 6 3 Reovirus sigma C capsid protein Cep57_CLD PF14073.1 EDO06130.1 - 0.0089 15.8 3.3 0.0089 15.8 2.3 6.5 4 3 2 6 6 6 1 Centrosome localisation domain of Cep57 AAA_15 PF13175.1 EDO06130.1 - 0.0099 14.9 9.5 0.26 10.2 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EDO06130.1 - 0.019 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain APG6 PF04111.7 EDO06130.1 - 0.034 13.2 60.4 0.0084 15.1 7.5 5.5 3 2 1 5 5 5 0 Autophagy protein Apg6 LacI PF00356.16 EDO06130.1 - 0.087 12.4 0.8 1.7 8.3 0.0 3.1 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family ABC_tran PF00005.22 EDO06130.1 - 0.095 13.0 16.8 8.3 6.7 5.5 5.0 3 1 0 3 3 3 0 ABC transporter PA28_beta PF02252.13 EDO06130.1 - 0.3 10.5 6.1 0.18 11.2 0.5 2.8 3 0 0 3 3 3 0 Proteasome activator pa28 beta subunit Tropomyosin_1 PF12718.2 EDO06130.1 - 0.93 9.3 78.5 0.11 12.3 6.4 6.7 5 1 1 6 6 6 0 Tropomyosin like Spc7 PF08317.6 EDO06130.1 - 1.5 7.3 60.1 0.015 13.9 3.3 5.7 3 2 2 5 5 5 0 Spc7 kinetochore protein Histone PF00125.19 EDO06132.1 - 1.1e-18 67.1 0.0 1.5e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDO06132.1 - 3.7e-06 26.8 0.2 8e-06 25.8 0.2 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EDO06132.1 - 0.0011 19.1 0.1 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EDO06132.1 - 0.11 11.9 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Replication protein C N-terminal domain CactinC_cactus PF09732.4 EDO06133.1 - 0.067 12.7 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein Myb_DNA-binding PF00249.26 EDO06134.1 - 7.4e-16 57.9 0.7 4.9e-07 29.6 0.1 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain DnaJ PF00226.26 EDO06134.1 - 6.8e-13 48.1 0.5 2.2e-12 46.4 0.4 2.0 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-bind_6 PF13921.1 EDO06134.1 - 5.7e-09 35.9 0.8 0.0002 21.3 0.0 3.8 2 2 1 3 3 3 2 Myb-like DNA-binding domain RRM_1 PF00076.17 EDO06135.1 - 4.1e-58 192.9 3.7 4.4e-17 61.4 0.0 6.1 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06135.1 - 8.1e-48 160.2 0.2 2.3e-13 49.9 0.0 5.7 5 1 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06135.1 - 2.2e-35 120.2 0.1 2.6e-10 39.9 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C97 PF05903.9 EDO06137.1 - 1.2e-30 106.2 0.1 1.8e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain POTRA_1 PF08478.5 EDO06137.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 POTRA domain, FtsQ-type Symplekin_C PF12295.3 EDO06138.1 - 1e-24 87.4 0.2 2.5e-24 86.2 0.1 1.6 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal HEAT PF02985.17 EDO06138.1 - 0.063 13.3 0.1 0.27 11.4 0.1 2.2 1 0 0 1 1 1 0 HEAT repeat PCI PF01399.22 EDO06140.1 - 4e-09 36.7 0.4 1.1e-08 35.2 0.0 2.0 2 0 0 2 2 2 1 PCI domain BCL_N PF04714.8 EDO06140.1 - 0.078 12.5 0.7 0.18 11.3 0.5 1.6 1 0 0 1 1 1 0 BCL7, N-terminal conserver region RPN7 PF10602.4 EDO06141.1 - 3.9e-52 176.1 1.2 5.9e-52 175.6 0.9 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EDO06141.1 - 8.6e-13 48.5 0.3 3.6e-12 46.5 0.1 2.1 2 0 0 2 2 2 1 PCI domain TPR_11 PF13414.1 EDO06141.1 - 0.033 13.8 0.6 0.087 12.4 0.0 2.0 2 0 0 2 2 2 0 TPR repeat Ribosomal_L22e PF01776.12 EDO06142.1 - 4.4e-48 161.9 0.7 5.2e-48 161.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family RRM_1 PF00076.17 EDO06143.1 - 9.8e-18 63.5 0.0 1.4e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06143.1 - 8.4e-16 57.7 0.0 1.3e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06143.1 - 8.9e-09 35.0 0.0 1.3e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EDO06144.1 - 2.6e-09 37.0 0.0 5.3e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EDO06144.1 - 5.9e-08 32.2 0.0 2.4e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06144.1 - 0.00062 19.6 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.19 EDO06145.1 - 1.7e-33 114.5 0.4 2.7e-33 113.9 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDO06145.1 - 0.00024 21.1 0.0 0.00037 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDO06145.1 - 0.005 16.8 0.0 0.0097 15.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EDO06145.1 - 0.12 12.1 0.1 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EDO06146.1 - 2.3e-25 88.5 0.0 3.1e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDO06146.1 - 0.00028 20.8 0.0 0.00055 19.9 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TPR_11 PF13414.1 EDO06147.1 - 3.4e-18 65.0 6.9 1.9e-05 24.1 0.0 6.3 5 1 1 6 6 6 4 TPR repeat TPR_14 PF13428.1 EDO06147.1 - 3.8e-16 58.1 0.7 0.12 13.1 0.0 8.2 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EDO06147.1 - 4.8e-12 45.4 0.6 0.39 11.2 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO06147.1 - 5.3e-12 44.6 8.8 0.022 14.6 0.0 7.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDO06147.1 - 1.8e-11 44.4 0.5 0.15 12.7 0.0 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EDO06147.1 - 3.7e-10 38.9 11.8 0.0036 16.8 0.1 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDO06147.1 - 4.9e-09 36.3 8.7 0.00013 22.2 0.1 6.9 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDO06147.1 - 1.1e-08 34.9 8.6 0.061 13.2 0.0 7.5 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO06147.1 - 2.7e-07 29.9 1.7 0.21 11.4 0.0 6.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDO06147.1 - 1.8e-06 27.2 2.5 6.3 6.8 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDO06147.1 - 2.3e-05 24.2 11.8 0.25 11.6 0.0 7.4 9 0 0 9 9 7 1 Tetratricopeptide repeat Apc3 PF12895.2 EDO06147.1 - 0.00064 19.8 16.1 0.16 12.0 0.4 6.3 5 3 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EDO06147.1 - 0.0073 16.1 0.3 4.1 7.3 0.0 4.2 4 1 1 5 5 4 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EDO06147.1 - 0.039 14.1 0.1 23 5.1 0.0 3.2 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation DUF3854 PF12965.2 EDO06147.1 - 0.045 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) HEAT_2 PF13646.1 EDO06147.1 - 0.049 13.9 0.0 7.7 6.8 0.0 3.2 2 0 0 2 2 2 0 HEAT repeats Apc5 PF12862.2 EDO06147.1 - 0.066 13.0 1.0 6.5 6.6 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 ATP-synt_ab_C PF00306.22 EDO06147.1 - 0.52 10.7 3.5 0.52 10.7 0.2 2.8 3 0 0 3 3 2 0 ATP synthase alpha/beta chain, C terminal domain Ribosomal_L19 PF01245.15 EDO06148.1 - 1e-16 60.7 0.7 2.9e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L19 Slu7 PF11708.3 EDO06149.1 - 1.9e-60 204.6 0.0 2.5e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EDO06149.1 - 0.047 13.3 0.1 0.093 12.4 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-DHHC PF01529.15 EDO06150.1 - 1.2e-08 34.6 28.5 1.2e-08 34.5 12.0 3.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase CRT-like PF08627.5 EDO06150.1 - 2.2 8.2 8.0 0.26 11.2 2.3 1.8 2 0 0 2 2 2 0 CRT-like MACPF PF01823.14 EDO06153.1 - 3.3e-28 98.8 2.8 3.8e-21 75.7 0.2 2.4 1 1 1 2 2 2 2 MAC/Perforin domain MOSC_N PF03476.11 EDO06153.1 - 0.1 12.3 0.1 4.2 7.1 0.0 2.5 3 0 0 3 3 3 0 MOSC N-terminal beta barrel domain RNA_pol_Rpb2_6 PF00562.23 EDO06154.1 - 1.3e-113 379.6 0.2 1.9e-113 379.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EDO06154.1 - 4.9e-31 107.2 0.0 7.6e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EDO06154.1 - 9.3e-23 79.7 0.0 2.2e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 EDO06154.1 - 9.9e-19 67.3 0.0 9e-18 64.3 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EDO06154.1 - 0.0026 17.1 0.1 0.0096 15.3 0.0 2.0 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 2 zf-Mss51 PF13824.1 EDO06154.1 - 0.081 12.7 2.0 11 5.9 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF1610 PF07754.6 EDO06154.1 - 0.6 10.2 3.4 0.4 10.8 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) PLDc_2 PF13091.1 EDO06156.1 - 1.7e-22 79.4 0.0 1.2e-12 47.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EDO06156.1 - 1.7e-12 46.6 0.6 9.5e-05 22.0 0.3 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif Haemagg_act PF05860.8 EDO06157.1 - 0.77 9.5 2.9 8.7 6.1 0.1 2.7 3 0 0 3 3 3 0 haemagglutination activity domain MACPF PF01823.14 EDO06158.1 - 3.3e-26 92.2 0.1 5.5e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain Colicin PF01024.14 EDO06158.1 - 0.051 13.1 0.8 0.083 12.4 0.5 1.4 1 0 0 1 1 1 0 Colicin pore forming domain MRP-L47 PF06984.8 EDO06159.1 - 7.1e-21 73.9 0.2 1.5e-19 69.7 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF3172 PF11371.3 EDO06160.1 - 0.04 13.4 0.1 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) DUF1832 PF08870.6 EDO06160.1 - 0.074 12.7 0.1 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1832) RNA_pol_Rpb2_6 PF00562.23 EDO06161.1 - 1.1e-119 399.6 0.0 1.9e-119 398.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EDO06161.1 - 9.5e-59 197.7 0.0 1.3e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EDO06161.1 - 2.6e-48 163.9 0.0 5.9e-48 162.8 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EDO06161.1 - 6.2e-32 109.7 0.0 1.5e-31 108.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EDO06161.1 - 4.6e-25 87.1 0.0 9.3e-25 86.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 EDO06161.1 - 1.4e-22 79.2 0.0 3.3e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EDO06161.1 - 8.8e-22 76.8 2.2 2.2e-21 75.5 1.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Dr_adhesin PF12393.3 EDO06161.1 - 0.023 14.7 0.9 0.061 13.4 0.6 1.8 1 0 0 1 1 1 0 Dr family adhesin VIT1 PF01988.14 EDO06163.1 - 1.1e-51 175.3 2.1 1.3e-51 175.1 1.5 1.0 1 0 0 1 1 1 1 VIT family Transmemb_17 PF09799.4 EDO06163.1 - 0.032 14.5 0.9 0.064 13.5 0.6 1.5 1 0 0 1 1 1 0 Predicted membrane protein DUF1129 PF06570.6 EDO06163.1 - 0.059 12.6 1.8 0.68 9.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Kelch_1 PF01344.20 EDO06164.1 - 2e-44 148.9 8.3 3.9e-11 42.2 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 EDO06164.1 - 3.9e-40 135.3 10.1 9.8e-11 41.2 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EDO06164.1 - 7.7e-38 127.1 9.9 3.5e-09 36.4 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 EDO06164.1 - 4.7e-35 118.9 10.7 4.1e-09 36.2 0.0 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_2 PF07646.10 EDO06164.1 - 5.4e-31 105.1 8.5 8.3e-08 31.7 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EDO06164.1 - 9.3e-31 105.2 21.3 4.2e-07 29.9 0.0 7.4 7 1 0 7 7 7 6 Galactose oxidase, central domain BTB PF00651.26 EDO06164.1 - 3.3e-16 59.2 0.5 1.3e-15 57.3 0.1 2.0 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 EDO06164.1 - 0.0035 17.1 0.7 0.11 12.3 0.1 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch PUB PF09409.5 EDO06164.1 - 0.16 11.7 0.0 23 4.8 0.0 2.4 2 0 0 2 2 2 0 PUB domain PEPcase PF00311.12 EDO06165.1 - 1.1e-215 718.0 0.0 1.3e-215 717.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.1 EDO06165.1 - 2.5e-05 22.8 0.0 3.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase IncA PF04156.9 EDO06166.1 - 4e-06 26.5 87.1 0.031 13.8 5.0 8.8 6 2 2 8 8 8 5 IncA protein CENP-Q PF13094.1 EDO06166.1 - 0.0013 18.8 0.2 0.0013 18.8 0.1 9.3 7 4 2 9 9 9 1 CENP-Q, a CENPA-CAD centromere complex subunit Hat1_N PF10394.4 EDO06166.1 - 0.17 11.9 0.7 0.5 10.4 0.5 1.8 1 0 0 1 1 1 0 Histone acetyl transferase HAT1 N-terminus Mnd1 PF03962.10 EDO06166.1 - 0.39 10.3 51.0 0.028 14.0 2.1 7.2 7 0 0 7 7 7 0 Mnd1 family GAS PF13851.1 EDO06166.1 - 1.8 7.7 61.6 0.13 11.4 0.6 8.7 6 2 2 9 9 9 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.7 EDO06166.1 - 2.5 8.3 19.1 22 5.3 0.0 7.6 7 1 0 7 7 7 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 EDO06166.1 - 2.6 7.0 65.8 0.31 10.0 3.1 7.5 6 1 0 7 7 7 0 Autophagy protein Apg6 HVSL PF09749.4 EDO06168.1 - 0.065 12.2 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein UCR_hinge PF02320.11 EDO06170.1 - 3.4e-17 62.1 2.5 5.1e-17 61.5 1.8 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein PRP3 PF08572.5 EDO06171.1 - 8.1e-47 159.4 13.1 8.1e-47 159.4 9.1 2.0 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EDO06171.1 - 1.6e-26 92.4 0.1 1.6e-26 92.4 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) HORMA PF02301.13 EDO06172.1 - 1.5e-53 181.3 0.0 2.2e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 HORMA domain Gar1 PF04410.9 EDO06173.1 - 1.6e-37 128.3 0.0 2.1e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region FtsJ PF01728.14 EDO06174.1 - 2.1e-52 177.7 0.1 2.6e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EDO06174.1 - 0.0013 18.3 0.2 0.038 13.5 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO06174.1 - 0.004 16.8 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NSP13 PF06460.7 EDO06174.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP13 Thioredoxin_8 PF13905.1 EDO06175.1 - 7.2e-49 163.8 0.6 2.2e-24 85.3 0.1 2.6 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EDO06175.1 - 1.1e-08 35.2 0.0 0.00052 20.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.1 EDO06175.1 - 0.0025 17.6 1.2 0.022 14.5 0.0 2.8 3 1 0 3 3 3 1 Thioredoxin-like domain MIP-T3 PF10243.4 EDO06177.1 - 0.0087 14.5 15.0 0.0073 14.8 10.4 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 EDO06177.1 - 0.14 10.1 3.6 0.11 10.5 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Borrelia_P83 PF05262.6 EDO06177.1 - 0.17 10.0 10.3 0.16 10.2 7.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Cnd1 PF12717.2 EDO06178.1 - 5.1e-46 156.7 7.6 1.8e-45 154.9 0.8 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EDO06178.1 - 1.4e-05 23.6 1.3 1.4e-05 23.6 0.9 3.3 3 1 0 3 3 3 2 Adaptin N terminal region XRN_N PF03159.13 EDO06179.1 - 1.8e-93 312.3 1.0 2.2e-93 312.0 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus VWA_2 PF13519.1 EDO06180.1 - 0.0012 18.9 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain tRNA-synt_1b PF00579.20 EDO06181.1 - 4.6e-48 163.8 0.0 6.9e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) VESA1_N PF12785.2 EDO06182.1 - 1.8e-195 650.2 19.6 1.8e-195 650.2 13.6 2.8 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 DUF2524 PF10732.4 EDO06182.1 - 0.0021 18.1 0.0 0.86 9.7 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2524) GTPase_Cys_C PF12631.2 EDO06182.1 - 0.014 15.7 0.4 0.14 12.6 0.3 2.7 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE SF-assemblin PF06705.6 EDO06182.1 - 0.014 14.5 1.6 0.023 13.8 1.1 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin Sec8_exocyst PF04048.9 EDO06182.1 - 0.015 14.9 2.5 0.93 9.1 0.0 3.0 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Lac_bphage_repr PF06543.7 EDO06182.1 - 0.049 13.1 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor LXG PF04740.7 EDO06182.1 - 0.06 13.1 3.9 1 9.0 0.1 2.5 1 1 1 2 2 2 0 LXG domain of WXG superfamily Myosin_tail_1 PF01576.14 EDO06182.1 - 0.093 10.4 5.9 0.15 9.7 4.1 1.2 1 0 0 1 1 1 0 Myosin tail Perilipin PF03036.11 EDO06182.1 - 0.13 11.0 0.7 0.21 10.3 0.5 1.2 1 0 0 1 1 1 0 Perilipin family AAA_13 PF13166.1 EDO06182.1 - 0.24 9.8 1.1 0.4 9.1 0.8 1.2 1 0 0 1 1 1 0 AAA domain ApoLp-III PF07464.6 EDO06182.1 - 0.35 10.8 6.7 8.6 6.3 3.5 2.7 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TelA PF05816.6 EDO06182.1 - 0.36 9.5 5.1 3.7 6.1 1.0 2.1 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) IncA PF04156.9 EDO06182.1 - 0.58 9.7 7.0 3.1 7.3 4.9 2.0 1 1 0 1 1 1 0 IncA protein COG2 PF06148.6 EDO06182.1 - 0.59 10.0 2.4 1.9 8.3 0.2 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.2 EDO06182.1 - 0.64 9.8 10.3 0.36 10.6 4.2 2.3 2 0 0 2 2 2 0 Tropomyosin like Baculo_PEP_C PF04513.7 EDO06182.1 - 0.83 9.4 1.6 12 5.6 0.1 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.15 EDO06182.1 - 1.2 8.9 12.7 2.4 7.9 4.7 3.4 2 2 1 3 3 3 0 Prefoldin subunit DUF4618 PF15397.1 EDO06182.1 - 2.2 7.5 5.6 36 3.5 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Spc7 PF08317.6 EDO06182.1 - 2.8 6.4 10.0 0.32 9.6 3.8 1.7 2 1 0 2 2 2 0 Spc7 kinetochore protein RRF PF01765.14 EDO06182.1 - 3 7.2 4.8 1.2 8.6 1.1 1.9 1 1 1 2 2 2 0 Ribosome recycling factor TPR_MLP1_2 PF07926.7 EDO06182.1 - 4.9 6.8 10.2 11 5.7 3.9 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein VESA1_N PF12785.2 EDO06183.1 - 1.8e-223 742.6 20.9 1.8e-223 742.6 14.5 2.5 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 GTPase_Cys_C PF12631.2 EDO06183.1 - 0.002 18.4 0.5 2.9 8.3 0.1 3.1 3 0 0 3 3 3 2 Catalytic cysteine-containing C-terminus of GTPase, MnmE Chordopox_A30L PF06015.7 EDO06183.1 - 0.12 12.0 0.0 0.36 10.4 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus A30L protein F-box-like_2 PF13013.1 EDO06184.1 - 9.4e-10 38.1 1.0 1.3e-05 24.9 0.0 3.7 3 1 2 5 5 5 4 F-box-like domain Renin_r PF07850.9 EDO06185.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.6 1 1 1 2 2 2 0 Renin receptor-like protein VESA1_N PF12785.2 EDO06186.1 - 2.7e-208 692.5 18.6 2.7e-208 692.5 12.9 2.8 3 0 0 3 3 2 1 Variant erythrocyte surface antigen-1 DUF2524 PF10732.4 EDO06186.1 - 0.0023 18.0 0.0 0.88 9.7 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2524) GTPase_Cys_C PF12631.2 EDO06186.1 - 0.012 15.9 0.4 0.14 12.5 0.3 2.9 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE SF-assemblin PF06705.6 EDO06186.1 - 0.014 14.5 1.6 0.024 13.8 1.1 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin Sec8_exocyst PF04048.9 EDO06186.1 - 0.017 14.7 2.5 0.96 9.0 0.0 2.9 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Lac_bphage_repr PF06543.7 EDO06186.1 - 0.038 13.5 0.1 0.11 12.0 0.1 1.8 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor LXG PF04740.7 EDO06186.1 - 0.062 13.0 3.9 1.1 9.0 0.1 2.5 1 1 1 2 2 2 0 LXG domain of WXG superfamily Myosin_tail_1 PF01576.14 EDO06186.1 - 0.097 10.3 5.9 0.16 9.6 4.1 1.2 1 0 0 1 1 1 0 Myosin tail Perilipin PF03036.11 EDO06186.1 - 0.13 11.0 0.7 0.22 10.3 0.5 1.2 1 0 0 1 1 1 0 Perilipin family AAA_13 PF13166.1 EDO06186.1 - 0.24 9.7 1.1 0.41 9.0 0.8 1.2 1 0 0 1 1 1 0 AAA domain ApoLp-III PF07464.6 EDO06186.1 - 0.34 10.9 6.7 6.1 6.8 3.4 2.7 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TelA PF05816.6 EDO06186.1 - 0.37 9.4 5.1 3.9 6.0 1.0 2.1 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) DUF3584 PF12128.3 EDO06186.1 - 0.53 7.5 2.6 0.81 6.9 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 EDO06186.1 - 0.61 9.6 7.1 3.3 7.2 4.9 2.0 1 1 0 1 1 1 0 IncA protein COG2 PF06148.6 EDO06186.1 - 0.68 9.8 2.6 2 8.3 0.2 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.2 EDO06186.1 - 0.68 9.7 10.3 0.37 10.6 4.2 2.3 2 0 0 2 2 2 0 Tropomyosin like Prefoldin_2 PF01920.15 EDO06186.1 - 1.2 8.9 12.7 2.4 7.9 4.7 3.4 2 2 1 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.7 EDO06186.1 - 1.9 8.2 3.5 11 5.8 0.1 3.5 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 EDO06186.1 - 2.5 6.6 9.8 0.26 9.9 3.6 1.7 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF4618 PF15397.1 EDO06186.1 - 2.5 7.3 5.7 37 3.5 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) RRF PF01765.14 EDO06186.1 - 3 7.2 4.7 1.2 8.5 1.1 1.9 1 1 1 2 2 2 0 Ribosome recycling factor TPR_MLP1_2 PF07926.7 EDO06186.1 - 5.1 6.8 10.2 11 5.7 3.9 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein VESA1_N PF12785.2 EDO06187.1 - 1.7e-30 106.4 13.7 1.2e-27 97.0 5.5 3.1 1 1 1 2 2 2 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO06188.1 - 2.4e-182 607.0 47.9 2.4e-182 607.0 33.2 4.1 3 1 0 3 3 3 1 Variant erythrocyte surface antigen-1 Baculo_PEP_C PF04513.7 EDO06188.1 - 0.0063 16.3 0.8 0.097 12.5 0.6 2.8 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4175 PF13779.1 EDO06188.1 - 0.34 8.5 2.4 1.1 6.8 1.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4175) Proteasome PF00227.21 EDO06189.1 - 1.1e-26 93.3 0.2 2.1e-26 92.3 0.1 1.5 1 1 1 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO06189.1 - 1.8e-13 49.5 0.0 3.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Peptidase_S9 PF00326.16 EDO06190.1 - 8.6e-23 80.6 0.0 1.3e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DSHCT PF08148.7 EDO06191.1 - 2.1e-52 176.9 0.0 5.6e-52 175.5 0.0 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EDO06191.1 - 2.9e-22 78.9 0.0 5.2e-21 74.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO06191.1 - 2.3e-06 27.3 0.0 7.2e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO06191.1 - 0.00013 21.8 0.1 0.0012 18.7 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit IBN_N PF03810.14 EDO06192.1 - 2.1e-05 24.3 0.1 0.00044 20.0 0.1 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain WD40 PF00400.27 EDO06193.1 - 2.3e-07 30.4 5.8 9.6e-06 25.2 0.0 5.5 8 0 0 8 8 8 1 WD domain, G-beta repeat DUF974 PF06159.8 EDO06194.1 - 3.9e-05 23.2 0.2 0.00058 19.3 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF974) Prp19_bind PF06991.6 EDO06195.1 - 8.6e-66 222.0 28.8 8.6e-66 222.0 19.9 1.8 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain TMEM237 PF15383.1 EDO06195.1 - 0.49 9.4 5.5 1 8.4 3.8 1.6 1 0 0 1 1 1 0 Transmembrane protein 237 PhoQ_Sensor PF08918.5 EDO06195.1 - 6.1 6.3 6.6 0.4 10.1 0.7 1.9 2 1 0 2 2 2 0 PhoQ Sensor LSM PF01423.17 EDO06197.1 - 8.9e-15 54.0 0.5 1.2e-14 53.5 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDO06197.1 - 0.0018 18.1 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain RINGv PF12906.2 EDO06198.1 - 1.1e-13 51.0 3.5 2.1e-13 50.0 2.4 1.6 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.21 EDO06198.1 - 4.9e-10 39.3 0.2 5.1e-09 36.1 0.2 2.4 2 0 0 2 2 2 1 FHA domain zf-RING_2 PF13639.1 EDO06198.1 - 0.0017 18.1 2.5 0.0034 17.1 1.8 1.6 1 0 0 1 1 1 1 Ring finger domain FAST_1 PF06743.10 EDO06199.1 - 0.079 12.6 15.1 0.57 9.9 0.1 5.6 4 2 2 6 6 6 0 FAST kinase-like protein, subdomain 1 tRNA-synt_1 PF00133.17 EDO06200.1 - 0.1 10.6 0.0 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) RabGAP-TBC PF00566.13 EDO06202.1 - 7.4e-49 166.1 1.0 7.4e-49 166.1 0.7 1.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.27 EDO06204.1 - 1.9e-06 27.5 0.4 0.13 12.2 0.0 6.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Prismane PF03063.15 EDO06205.1 - 0.056 11.8 2.2 0.06 11.7 1.2 1.3 1 1 0 1 1 1 0 Prismane/CO dehydrogenase family Rep_fac_C PF08542.6 EDO06206.1 - 5.9e-17 61.4 0.0 4.1e-16 58.7 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EDO06206.1 - 3.4e-15 56.0 0.1 3e-14 52.9 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EDO06206.1 - 1.4e-14 54.4 0.0 2.5e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO06206.1 - 3.2e-08 33.7 0.3 1.4e-06 28.4 0.1 2.8 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.10 EDO06206.1 - 1.4e-07 30.6 0.0 1.9e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 EDO06206.1 - 1.2e-05 25.0 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO06206.1 - 1.4e-05 25.2 0.0 0.00023 21.2 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 EDO06206.1 - 3.3e-05 23.5 0.0 0.00011 21.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO06206.1 - 8.6e-05 22.2 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EDO06206.1 - 0.00025 20.7 0.0 0.00071 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EDO06206.1 - 0.00059 18.9 0.0 0.0016 17.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EDO06206.1 - 0.00065 19.6 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EDO06206.1 - 0.0014 18.1 0.4 0.027 13.9 0.0 2.5 2 1 1 3 3 3 1 DEAD/DEAH box helicase Mg_chelatase PF01078.16 EDO06206.1 - 0.0018 17.4 0.0 0.0038 16.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EDO06206.1 - 0.0019 17.2 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 EDO06206.1 - 0.016 14.8 0.0 0.043 13.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EDO06206.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EDO06206.1 - 0.022 14.4 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase ResIII PF04851.10 EDO06206.1 - 0.025 14.4 0.0 0.11 12.2 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 EDO06206.1 - 0.026 14.8 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EDO06206.1 - 0.026 14.4 0.0 0.11 12.3 0.0 2.1 1 1 2 3 3 3 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EDO06206.1 - 0.041 14.7 0.0 0.093 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EDO06206.1 - 0.055 12.3 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.8 EDO06206.1 - 0.056 12.1 0.0 0.38 9.4 0.0 2.0 2 0 0 2 2 2 0 TIP49 C-terminus AAA_33 PF13671.1 EDO06206.1 - 0.06 13.2 0.2 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain Torsin PF06309.6 EDO06206.1 - 0.067 13.0 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Torsin DNA_pol3_delta PF06144.8 EDO06206.1 - 0.1 12.0 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 1 0 DNA polymerase III, delta subunit AAA_10 PF12846.2 EDO06206.1 - 0.13 11.7 0.1 12 5.2 0.0 2.6 2 1 1 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 EDO06206.1 - 0.16 12.1 0.3 0.74 10.0 0.1 2.3 2 1 0 2 2 2 0 RNA helicase AAA PF00004.24 EDO06207.1 - 1.1e-10 41.8 0.2 1.1e-08 35.3 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDO06207.1 - 1.7e-05 24.2 0.1 0.00039 19.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO06207.1 - 3.2e-05 24.0 0.4 0.0011 19.1 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EDO06207.1 - 6.7e-05 22.9 0.1 0.045 13.7 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain AAA_14 PF13173.1 EDO06207.1 - 0.0001 22.1 0.2 0.0024 17.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EDO06207.1 - 0.00039 20.1 0.0 0.001 18.7 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EDO06207.1 - 0.00061 19.3 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 EDO06207.1 - 0.0025 17.2 0.0 0.0055 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EDO06207.1 - 0.004 16.8 0.3 0.059 13.0 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_23 PF13476.1 EDO06207.1 - 0.0043 17.3 1.2 0.0043 17.3 0.8 2.7 1 1 0 2 2 1 1 AAA domain T2SE PF00437.15 EDO06207.1 - 0.012 14.5 0.1 0.033 13.0 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 EDO06207.1 - 0.018 15.5 0.0 0.051 14.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein ABC_ATPase PF09818.4 EDO06207.1 - 0.019 13.5 0.0 0.033 12.7 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.18 EDO06207.1 - 0.026 14.4 0.0 0.094 12.6 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 EDO06207.1 - 0.041 13.5 1.2 0.11 12.1 0.1 2.2 3 0 0 3 3 3 0 NACHT domain AAA_10 PF12846.2 EDO06207.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain IF3_C PF00707.17 EDO06208.1 - 1.6e-07 30.9 0.1 7.3e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain Gp_dh_C PF02800.15 EDO06209.1 - 2.4e-70 235.0 0.0 3.2e-70 234.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EDO06209.1 - 3.1e-57 192.7 0.0 5.1e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EDO06209.1 - 0.016 15.1 0.0 0.059 13.2 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 EDO06209.1 - 0.027 13.9 0.0 0.077 12.5 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Cytochrom_C1 PF02167.10 EDO06210.1 - 5.6e-83 277.8 0.0 1.1e-82 276.9 0.0 1.4 2 0 0 2 2 2 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EDO06210.1 - 0.0024 18.0 0.0 0.0071 16.4 0.0 1.8 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EDO06210.1 - 0.016 16.0 0.0 0.049 14.4 0.0 1.9 1 0 0 1 1 1 0 Cytochrome c zf-C2H2_jaz PF12171.3 EDO06211.1 - 1.4e-07 31.4 1.8 2.5e-07 30.6 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDO06211.1 - 1.9e-06 27.8 1.6 3.8e-06 26.9 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 EDO06211.1 - 0.00035 20.0 0.8 0.001 18.5 0.5 1.8 1 0 0 1 1 1 1 U1 zinc finger DDE_Tnp_IS240 PF13610.1 EDO06211.1 - 0.0037 17.2 3.1 0.0063 16.4 2.2 1.3 1 0 0 1 1 1 1 DDE domain Med9 PF07544.8 EDO06211.1 - 0.0063 16.2 7.2 0.0079 15.9 3.3 2.1 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 zf-C2H2_2 PF12756.2 EDO06211.1 - 0.0098 15.9 1.0 0.0098 15.9 0.7 1.8 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Thy1 PF02511.10 EDO06211.1 - 0.012 15.0 0.2 0.014 14.7 0.1 1.2 1 0 0 1 1 1 0 Thymidylate synthase complementing protein Fucose_iso_N2 PF07882.7 EDO06211.1 - 0.2 11.2 3.1 0.31 10.6 2.1 1.3 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain GH-E PF14410.1 EDO06211.1 - 0.27 11.4 3.7 0.29 11.3 0.0 2.6 2 1 1 3 3 3 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Seryl_tRNA_N PF02403.17 EDO06211.1 - 4.2 7.4 14.4 4.4 7.3 7.4 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1411 PF07199.6 EDO06212.1 - 1.5e-93 311.6 0.0 1.9e-93 311.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1411) DUF1411 PF07199.6 EDO06213.1 - 1.8e-92 308.1 1.4 2.5e-92 307.6 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1411) PPP4R2 PF09184.6 EDO06213.1 - 0.0024 17.4 0.3 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 PPP4R2 Rep_3 PF01051.16 EDO06213.1 - 0.013 15.1 0.2 0.11 12.0 0.0 2.0 1 1 1 2 2 2 0 Initiator Replication protein Reo_sigmaC PF04582.7 EDO06213.1 - 0.1 11.7 0.2 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1411 PF07199.6 EDO06214.1 - 1.4e-74 249.7 9.2 3.9e-55 186.3 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1411) CDC73 PF05179.9 EDO06215.1 - 1.2e-38 133.1 0.2 1.6e-38 132.6 0.1 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family NUDIX PF00293.23 EDO06216.1 - 6.8e-22 77.5 0.0 8.3e-22 77.2 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain Phage_min_tail PF05939.8 EDO06216.1 - 0.083 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Phage minor tail protein Armet PF10208.4 EDO06216.1 - 0.088 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Endothelin PF00322.12 EDO06216.1 - 0.32 10.2 0.1 0.32 10.2 0.1 1.8 2 0 0 2 2 2 0 Endothelin family LSM PF01423.17 EDO06217.1 - 1.2e-11 43.9 0.0 1.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 EDO06217.1 - 0.0098 15.6 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain TSP_1 PF00090.14 EDO06218.1 - 0.0022 18.0 26.0 0.54 10.4 5.8 4.0 2 2 0 2 2 2 2 Thrombospondin type 1 domain PcF PF09461.5 EDO06218.1 - 0.7 9.8 14.7 0.54 10.1 0.2 4.2 5 0 0 5 5 5 0 Phytotoxin PcF protein Late_protein_L1 PF00500.13 EDO06219.1 - 0.11 11.0 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 L1 (late) protein VWA PF00092.23 EDO06220.1 - 2.4e-29 102.3 0.0 4.5e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EDO06220.1 - 2.8e-11 43.8 0.1 4.6e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4366 PF14283.1 EDO06220.1 - 0.00056 19.3 1.0 0.0019 17.6 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) vWA-TerF-like PF10138.4 EDO06220.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus NEL PF14496.1 EDO06221.1 - 0.075 12.3 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 C-terminal novel E3 ligase, LRR-interacting Ribosomal_S4 PF00163.14 EDO06222.1 - 1.1e-21 77.0 3.3 1.8e-21 76.3 2.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EDO06222.1 - 8.1e-13 47.5 0.3 2.8e-12 45.8 0.2 1.9 1 0 0 1 1 1 1 S4 domain SPT16 PF08644.6 EDO06224.1 - 2.5e-52 176.7 1.0 2.5e-52 176.7 0.7 2.6 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.19 EDO06224.1 - 2.9e-21 76.0 0.1 7e-21 74.7 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 Rtt106 PF08512.7 EDO06224.1 - 7.4e-20 70.7 0.1 1.3e-18 66.7 0.0 3.1 3 1 1 4 4 4 1 Histone chaperone Rttp106-like DUF1949 PF09186.6 EDO06224.1 - 0.015 14.9 0.0 0.063 12.8 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) RRM_1 PF00076.17 EDO06225.1 - 1.6e-29 101.3 0.0 2.7e-17 62.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06225.1 - 1.4e-16 60.1 0.0 5.3e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06225.1 - 2e-06 27.5 0.0 0.0001 22.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDO06225.1 - 0.00011 22.0 0.1 0.36 10.7 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif SelP_N PF04592.9 EDO06225.1 - 0.37 10.1 2.0 0.49 9.7 1.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Proteasome PF00227.21 EDO06227.1 - 1.1e-33 116.0 0.4 1.3e-33 115.8 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Psu PF07455.6 EDO06227.1 - 0.016 14.6 0.0 0.083 12.3 0.0 1.8 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) Cyclin PF08613.6 EDO06228.1 - 5.8e-30 104.6 2.5 9e-30 104.0 1.7 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EDO06228.1 - 1.8e-11 43.6 0.4 2.9e-11 43.0 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ATP-synt_C PF00137.16 EDO06229.1 - 5.8e-29 99.7 28.4 4.8e-16 58.4 5.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF998 PF06197.8 EDO06229.1 - 0.52 9.6 18.9 0.048 12.9 8.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF998) GerA PF03323.8 EDO06229.1 - 7.5 4.5 8.2 4.8 5.1 1.1 2.3 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein PT-VENN PF04829.8 EDO06229.1 - 8.3 6.0 6.7 2.1e+02 1.5 4.6 2.6 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Ribosomal_L14 PF00238.14 EDO06230.1 - 4e-19 68.5 0.7 4.5e-19 68.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF2179 PF10035.4 EDO06230.1 - 0.078 12.5 0.2 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) SLBP_RNA_bind PF15247.1 EDO06231.1 - 2.3e-17 62.4 1.0 2.3e-17 62.4 0.7 2.0 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain PCIF1_WW PF12237.3 EDO06231.1 - 0.051 12.8 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain tRNA-synt_1d PF00750.14 EDO06233.1 - 4.9e-93 311.7 0.1 6.2e-93 311.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EDO06233.1 - 3.5e-22 78.5 0.1 3.2e-21 75.4 0.0 2.3 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EDO06233.1 - 5.4e-14 52.4 0.2 3.8e-13 49.7 0.0 2.4 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 EDO06233.1 - 0.011 14.8 0.1 0.023 13.8 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.17 EDO06233.1 - 0.064 11.2 0.0 0.095 10.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) PI3_PI4_kinase PF00454.22 EDO06234.1 - 8.4e-20 71.2 0.0 3.8e-19 69.0 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Ribosomal_L13 PF00572.13 EDO06235.1 - 1.4e-27 96.3 1.9 6.9e-27 94.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L13 DSBA PF01323.15 EDO06235.1 - 0.051 13.1 0.0 1.2 8.6 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain SNARE PF05739.14 EDO06236.1 - 1.2e-11 44.0 2.9 1.2e-11 44.0 2.0 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 EDO06236.1 - 0.01 15.8 1.5 0.36 10.8 0.1 3.1 2 2 0 2 2 2 0 Syntaxin-like protein Med30 PF11315.3 EDO06236.1 - 0.014 15.5 2.4 0.026 14.6 1.7 1.5 1 0 0 1 1 1 0 Mediator complex subunit 30 Myb_DNA-bind_5 PF13873.1 EDO06236.1 - 0.027 14.3 0.2 10 6.0 0.0 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Lipase_GDSL_3 PF14606.1 EDO06236.1 - 0.15 11.8 1.8 0.67 9.6 0.0 2.6 1 1 4 5 5 5 0 GDSL-like Lipase/Acylhydrolase family MutS_III PF05192.13 EDO06236.1 - 0.17 11.6 0.9 0.32 10.7 0.6 1.4 1 0 0 1 1 1 0 MutS domain III MCPsignal PF00015.16 EDO06236.1 - 0.17 11.3 2.8 0.16 11.4 0.9 1.7 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1411 PF07199.6 EDO06237.1 - 5e-98 326.2 0.0 6.9e-98 325.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1411) DUF1411 PF07199.6 EDO06238.1 - 1.9e-100 334.1 0.0 3.3e-100 333.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1411) RasGAP_C PF03836.10 EDO06238.1 - 0.0043 16.7 0.9 0.0073 15.9 0.6 1.3 1 0 0 1 1 1 1 RasGAP C-terminus DUF3066 PF11266.3 EDO06238.1 - 0.11 12.2 0.2 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3066) Chordopox_G2 PF05796.7 EDO06238.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.4 1 1 0 1 1 1 0 Chordopoxvirus protein G2 Fork_head PF00250.13 EDO06238.1 - 0.3 11.1 2.9 0.72 9.9 0.2 2.3 2 1 0 2 2 2 0 Fork head domain CDC73 PF05179.9 EDO06239.1 - 9.9e-39 133.3 0.1 1.3e-38 132.8 0.1 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family NUDIX PF00293.23 EDO06240.1 - 2e-21 76.0 0.0 2.5e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain Phage_min_tail PF05939.8 EDO06240.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Phage minor tail protein Endothelin PF00322.12 EDO06240.1 - 0.32 10.2 0.1 0.32 10.2 0.1 1.9 2 0 0 2 2 2 0 Endothelin family LSM PF01423.17 EDO06241.1 - 1.2e-11 43.9 0.0 1.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 EDO06241.1 - 0.0098 15.6 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain VWA PF00092.23 EDO06242.1 - 1.8e-05 24.5 0.1 0.00013 21.7 0.0 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 EDO06242.1 - 0.0022 18.1 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain NVEALA PF14055.1 EDO06242.1 - 2.6 7.7 5.1 0.7 9.6 0.5 2.2 2 0 0 2 2 2 0 NVEALA protein DUF1411 PF07199.6 EDO06243.1 - 1.1e-135 449.1 0.3 1.2e-104 347.9 0.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1411) SR-25 PF10500.4 EDO06243.1 - 0.018 14.4 7.0 0.038 13.4 4.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TerD PF02342.13 EDO06243.1 - 0.024 13.9 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 TerD domain DUF605 PF04652.11 EDO06243.1 - 0.029 13.7 23.6 0.037 13.4 16.4 1.2 1 0 0 1 1 1 0 Vta1 like TFIIF_alpha PF05793.7 EDO06243.1 - 0.58 8.4 11.5 0.92 7.8 8.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) VWA PF00092.23 EDO06244.1 - 1.2e-14 54.4 0.4 1.8e-08 34.3 0.1 2.8 2 1 0 2 2 2 2 von Willebrand factor type A domain TSP_1 PF00090.14 EDO06244.1 - 0.0017 18.4 23.4 0.035 14.2 0.7 3.9 3 1 0 3 3 3 2 Thrombospondin type 1 domain NCD3G PF07562.9 EDO06244.1 - 0.032 13.9 1.7 8.4 6.2 0.1 2.9 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR FTR1 PF03239.9 EDO06244.1 - 0.28 10.1 0.0 0.61 8.9 0.0 1.5 1 0 0 1 1 1 0 Iron permease FTR1 family LSM PF01423.17 EDO06245.1 - 1.2e-11 43.9 0.0 1.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 EDO06245.1 - 0.0098 15.6 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain NUDIX PF00293.23 EDO06246.1 - 2e-21 76.0 0.0 2.5e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain Phage_min_tail PF05939.8 EDO06246.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Phage minor tail protein Endothelin PF00322.12 EDO06246.1 - 0.32 10.2 0.1 0.32 10.2 0.1 1.9 2 0 0 2 2 2 0 Endothelin family zf-CDGSH PF09360.5 EDO06247.1 - 2.4e-10 40.0 0.5 3.5e-10 39.5 0.3 1.3 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type zf-DHHC PF01529.15 EDO06248.1 - 3.5e-35 120.9 9.8 3.5e-35 120.9 6.8 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase Pox_F17 PF04767.7 EDO06248.1 - 4.1 7.7 5.3 1.4 9.2 1.6 1.7 2 0 0 2 2 2 0 DNA-binding 11 kDa phosphoprotein DUF1014 PF06244.7 EDO06249.1 - 1.1e-27 96.6 4.0 1.1e-27 96.6 2.8 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 EDO06249.1 - 0.026 14.7 1.4 0.026 14.7 1.0 2.7 2 1 0 2 2 2 0 HMG (high mobility group) box NHS PF15273.1 EDO06249.1 - 2.6 6.5 5.4 3 6.3 3.7 1.1 1 0 0 1 1 1 0 NHS-like DSS1_SEM1 PF05160.8 EDO06250.1 - 0.00038 20.1 12.8 0.00069 19.3 8.9 1.6 1 1 0 1 1 1 1 DSS1/SEM1 family Adaptin_N PF01602.15 EDO06251.1 - 7.7e-67 225.7 14.7 1e-66 225.3 10.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EDO06251.1 - 2e-24 86.1 0.1 6.4e-24 84.4 0.1 1.9 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EDO06251.1 - 1.8e-08 34.5 0.9 0.86 9.9 0.0 5.2 2 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EDO06251.1 - 0.00043 20.1 5.2 3.1 8.1 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat Cript PF10235.4 EDO06252.1 - 5.9e-19 68.2 10.8 5.9e-19 68.2 7.5 1.5 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DUF1272 PF06906.6 EDO06252.1 - 0.03 14.1 2.7 0.03 14.1 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.2 EDO06252.1 - 1.9 8.3 16.5 68 3.3 11.4 2.6 1 1 0 1 1 1 0 Double zinc ribbon HIPIP PF01355.12 EDO06252.1 - 7.3 6.8 12.4 31 4.8 5.3 2.7 1 1 1 2 2 2 0 High potential iron-sulfur protein Dynamin_M PF01031.15 EDO06253.1 - 4.7e-86 288.2 0.0 9.6e-86 287.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EDO06253.1 - 1.8e-45 154.7 0.0 8.2e-45 152.6 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EDO06253.1 - 1.7e-18 66.2 1.1 6.6e-18 64.4 0.8 2.1 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EDO06253.1 - 0.026 14.4 0.0 0.2 11.5 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase DIRP PF06584.8 EDO06253.1 - 0.055 13.3 0.2 0.21 11.4 0.1 2.0 1 0 0 1 1 1 0 DIRP FliG_N PF14842.1 EDO06253.1 - 0.058 13.5 0.4 3.3 7.8 0.1 3.0 2 0 0 2 2 2 0 FliG N-terminal domain DUF3752 PF12572.3 EDO06254.1 - 0.0011 19.0 0.2 0.0025 17.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Peptidase_M22 PF00814.20 EDO06255.1 - 3e-74 249.9 0.0 3.5e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family APH PF01636.18 EDO06255.1 - 0.046 13.4 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Prok-RING_2 PF14445.1 EDO06255.1 - 0.093 12.6 0.2 0.28 11.1 0.2 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 PCI PF01399.22 EDO06256.1 - 1.5e-11 44.5 3.3 8.3e-11 42.1 0.1 2.8 2 1 1 3 3 3 1 PCI domain SpoU_methylase PF00588.14 EDO06258.1 - 1.3e-05 25.1 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family LRR_4 PF12799.2 EDO06259.1 - 4.8e-33 112.2 26.2 1.8e-09 37.0 0.8 6.4 3 1 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDO06259.1 - 1.1e-29 101.9 50.6 1.5e-08 34.2 3.4 4.7 1 1 6 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 EDO06259.1 - 4e-15 53.5 18.4 0.33 11.1 0.0 8.8 7 2 1 8 8 8 6 Leucine Rich Repeat LRR_7 PF13504.1 EDO06259.1 - 1.8e-11 42.2 14.3 6.1 7.5 0.0 9.0 8 1 1 9 9 9 5 Leucine rich repeat LRR_9 PF14580.1 EDO06259.1 - 1.8e-11 43.8 9.8 1e-07 31.7 2.8 3.1 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.1 EDO06259.1 - 3.1e-11 42.1 18.9 1.1 9.5 0.1 8.5 5 1 3 8 8 8 5 Leucine Rich repeat DUF2322 PF10084.4 EDO06259.1 - 0.14 11.8 1.0 6 6.6 0.1 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) WD40 PF00400.27 EDO06260.1 - 1.4e-61 202.3 35.1 1.1e-13 50.5 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EDO06260.1 - 0.017 13.2 8.6 0.79 7.7 2.3 3.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EDO06260.1 - 0.049 13.9 0.1 0.47 10.7 0.0 2.7 2 0 0 2 2 2 0 PQQ-like domain Nucleoporin_N PF08801.6 EDO06260.1 - 0.66 8.6 6.7 26 3.4 0.0 3.7 2 2 1 3 3 3 0 Nup133 N terminal like RPAP1_C PF08620.5 EDO06261.1 - 4e-22 77.8 0.0 9.5e-22 76.6 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EDO06261.1 - 0.0013 18.2 0.6 0.0032 17.0 0.0 2.0 2 0 0 2 2 2 1 RPAP1-like, N-terminal FAST_1 PF06743.10 EDO06262.1 - 0.027 14.1 0.1 0.2 11.3 0.1 2.3 1 1 1 2 2 2 0 FAST kinase-like protein, subdomain 1 WD40 PF00400.27 EDO06263.1 - 1.7e-77 252.7 33.5 9.3e-13 47.5 0.2 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 EDO06263.1 - 4.4e-14 52.2 0.6 7.7e-14 51.4 0.4 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EDO06263.1 - 8e-07 27.5 0.6 1.7 6.6 0.1 4.3 2 2 1 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDO06263.1 - 0.0001 21.2 3.8 0.068 11.9 0.1 2.7 2 1 0 3 3 3 2 Nup133 N terminal like DUF1258 PF06869.7 EDO06263.1 - 0.094 11.7 0.0 7.2 5.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) HTH_9 PF08221.6 EDO06264.1 - 6.4e-10 38.7 2.3 1.2e-09 37.8 0.1 2.7 4 0 0 4 4 4 1 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 EDO06264.1 - 0.031 13.8 0.3 3.5 7.0 0.0 2.3 1 1 0 2 2 2 0 RNA polymerase III subunit RPC82 DUF3988 PF13149.1 EDO06264.1 - 0.2 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3988) DUF1049 PF06305.6 EDO06265.1 - 0.00032 20.1 0.0 0.00032 20.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) FtsX PF02687.16 EDO06265.1 - 0.0086 15.8 0.3 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 FtsX-like permease family Yip1 PF04893.12 EDO06265.1 - 0.014 14.8 2.2 0.02 14.4 1.5 1.1 1 0 0 1 1 1 0 Yip1 domain DctQ PF04290.7 EDO06265.1 - 0.089 12.5 1.7 0.12 12.1 1.2 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component TMEM190 PF15431.1 EDO06265.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 190 DUF2721 PF11026.3 EDO06265.1 - 0.18 11.4 5.2 0.69 9.5 3.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) HAMP PF00672.20 EDO06265.1 - 0.45 10.7 5.7 0.82 9.8 0.0 2.2 2 0 0 2 2 2 0 HAMP domain ATP_synt_I PF03899.10 EDO06265.1 - 0.47 10.6 5.3 1.2 9.3 3.7 1.6 1 1 0 1 1 1 0 ATP synthase I chain Ribosomal_L11_N PF03946.9 EDO06266.1 - 3.2e-18 64.9 0.0 4.6e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EDO06266.1 - 1.3e-11 44.4 0.1 2.2e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain TraH PF06122.6 EDO06266.1 - 0.12 11.1 0.3 0.21 10.3 0.1 1.4 1 1 1 2 2 2 0 Conjugative relaxosome accessory transposon protein Cbl_N PF02262.11 EDO06267.1 - 0.011 15.4 0.3 0.08 12.6 0.0 2.2 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 CPL PF08144.6 EDO06267.1 - 0.025 14.4 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 CPL (NUC119) domain GTP_EFTU PF00009.22 EDO06268.1 - 3.2e-24 85.3 1.6 7.8e-23 80.8 1.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EDO06268.1 - 6e-17 61.4 3.9 6.5e-17 61.3 0.8 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 EDO06268.1 - 2.7e-09 36.9 0.1 7.9e-08 32.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 EDO06268.1 - 1.9e-06 27.3 0.1 4.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EDO06268.1 - 6.8e-06 25.4 0.1 2.1e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EDO06268.1 - 0.00013 21.4 0.3 0.00036 20.0 0.2 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EDO06268.1 - 0.00048 20.6 0.0 0.0012 19.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 EDO06268.1 - 0.0021 17.3 1.8 0.0025 17.0 0.0 2.1 3 0 0 3 3 3 1 Ferrous iron transport protein B Arf PF00025.16 EDO06268.1 - 0.0064 15.7 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU_D4 PF14578.1 EDO06268.1 - 0.0098 15.5 1.0 0.09 12.4 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 4 AIG1 PF04548.11 EDO06268.1 - 0.05 12.7 0.1 0.11 11.5 0.1 1.6 1 0 0 1 1 1 0 AIG1 family PseudoU_synth_1 PF01416.15 EDO06270.1 - 4.5e-09 36.6 0.0 1.3e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 tRNA pseudouridine synthase Ribosomal_S11 PF00411.14 EDO06271.1 - 1.3e-40 137.9 0.3 2e-40 137.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 EDO06271.1 - 0.019 13.8 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Toprim_3 PF13362.1 EDO06271.1 - 0.079 13.2 1.7 0.62 10.3 0.1 2.2 1 1 0 2 2 2 0 Toprim domain Pilus_CpaD PF09476.5 EDO06271.1 - 0.096 12.1 0.2 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Mon1 PF03164.9 EDO06272.1 - 0.32 9.5 0.3 0.59 8.6 0.2 1.3 1 0 0 1 1 1 0 Trafficking protein Mon1 DUF3827 PF12877.2 EDO06272.1 - 2.2 6.2 5.5 3.6 5.5 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Macoilin PF09726.4 EDO06272.1 - 2.9 6.0 3.4 4.4 5.4 2.3 1.1 1 0 0 1 1 1 0 Transmembrane protein NIF PF03031.13 EDO06273.1 - 3.6e-36 124.2 0.3 4.5e-36 123.9 0.2 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BolA PF01722.13 EDO06274.1 - 2.1e-20 72.4 0.0 2.4e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein zf-B_box PF00643.19 EDO06276.1 - 5.4e-15 54.9 13.6 3.1e-07 30.1 1.9 2.5 2 0 0 2 2 2 2 B-box zinc finger PARP PF00644.15 EDO06276.1 - 0.0038 16.6 0.0 0.015 14.7 0.0 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain DUF2318 PF10080.4 EDO06276.1 - 0.18 11.5 3.1 0.44 10.3 1.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) zf-C3HC4_4 PF15227.1 EDO06277.1 - 0.00035 20.3 2.8 0.00085 19.1 1.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EDO06277.1 - 0.0077 16.2 5.4 0.0077 16.2 3.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Egg_lysin PF01303.12 EDO06277.1 - 0.051 13.5 0.2 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) zf-C3HC4 PF00097.20 EDO06277.1 - 0.058 13.0 3.5 0.14 11.8 2.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO06277.1 - 0.2 11.3 5.2 0.46 10.2 3.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EDO06277.1 - 0.43 10.4 7.9 0.17 11.7 3.6 1.7 2 0 0 2 2 2 0 Ring finger domain AP2 PF00847.15 EDO06278.1 - 2.4e-07 30.8 7.2 8.4e-05 22.6 0.7 2.4 2 0 0 2 2 2 2 AP2 domain DCX PF03607.12 EDO06279.1 - 2e-10 40.0 0.0 4.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Doublecortin p25-alpha PF05517.7 EDO06279.1 - 6.2e-08 33.0 0.2 1.1e-07 32.2 0.1 1.5 1 0 0 1 1 1 1 p25-alpha eIF2A PF08662.6 EDO06280.1 - 2e-29 102.6 0.2 1.7e-21 76.8 0.2 4.5 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EDO06280.1 - 4.6e-05 22.9 0.1 0.0003 20.3 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06280.1 - 0.0034 17.3 0.0 0.013 15.4 0.0 2.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EDO06280.1 - 0.0051 16.6 6.9 7 6.7 0.0 4.7 5 1 0 5 5 5 2 WD domain, G-beta repeat Complex1_LYR_2 PF13233.1 EDO06280.1 - 0.21 12.0 2.9 0.53 10.7 0.6 2.3 2 0 0 2 2 2 0 Complex1_LYR-like UbiA PF01040.13 EDO06281.1 - 1e-25 90.4 11.0 1.4e-25 90.0 7.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosomal_S24e PF01282.14 EDO06282.1 - 4.6e-30 103.2 0.0 7.3e-30 102.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e DEAD PF00270.24 EDO06283.1 - 1.5e-40 138.4 0.1 1.6e-38 131.8 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO06283.1 - 9.7e-27 92.6 0.1 2.5e-26 91.3 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EDO06283.1 - 0.018 15.2 1.1 0.23 11.6 0.0 3.1 3 1 0 3 3 3 0 AAA domain WD40 PF00400.27 EDO06284.1 - 4.3e-26 89.8 13.8 1.2e-09 37.6 0.6 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat CLTH PF10607.4 EDO06284.1 - 0.0057 16.3 0.9 0.01 15.5 0.6 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PUF PF00806.14 EDO06285.1 - 5.8e-53 173.4 8.4 2.9e-07 29.5 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF1732 PF08340.6 EDO06285.1 - 0.081 12.7 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) CAF1 PF04857.15 EDO06286.1 - 2.2e-14 53.4 0.0 1.6e-08 34.2 0.0 2.0 2 0 0 2 2 2 2 CAF1 family ribonuclease RRN3 PF05327.6 EDO06288.1 - 8.6e-40 136.3 0.4 1.4e-38 132.3 0.2 2.3 2 1 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF3223 PF11523.3 EDO06288.1 - 0.0042 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3223) AMMECR1 PF01871.12 EDO06289.1 - 7.3e-40 135.8 0.0 8.6e-40 135.6 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 EF_TS PF00889.14 EDO06291.1 - 2.7e-32 111.8 0.5 4.5e-16 58.8 0.0 2.2 2 0 0 2 2 2 2 Elongation factor TS Sec1 PF00995.18 EDO06292.1 - 2.6e-116 389.5 0.0 3.1e-116 389.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family RabGAP-TBC PF00566.13 EDO06293.1 - 2.5e-28 99.0 10.8 2.7e-26 92.4 7.5 2.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain NUC153 PF08159.7 EDO06294.1 - 0.0033 16.9 1.5 0.0071 15.9 1.1 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EDO06294.1 - 0.037 13.9 1.1 11 6.0 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF3991 PF13154.1 EDO06294.1 - 0.14 12.3 1.8 0.41 10.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3991) DUF2077 PF09850.4 EDO06294.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) zf-primase PF09329.6 EDO06296.1 - 2.7e-09 36.4 3.0 6.1e-09 35.3 0.8 2.6 2 0 0 2 2 2 1 Primase zinc finger Mcm10 PF09332.6 EDO06296.1 - 0.009 15.3 19.7 0.027 13.8 13.6 1.7 1 1 0 1 1 1 1 Mcm10 replication factor Atg31 PF09795.4 EDO06296.1 - 0.052 13.2 0.4 0.052 13.2 0.3 2.2 2 0 0 2 2 2 0 Autophagy-related protein 31 PDZ_1 PF12812.2 EDO06296.1 - 0.16 11.8 0.8 0.93 9.4 0.0 2.5 2 1 1 3 3 3 0 PDZ-like domain HAD_2 PF13419.1 EDO06297.1 - 5.3e-06 26.7 0.3 0.032 14.4 0.1 3.2 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EDO06297.1 - 0.0001 21.9 0.1 0.00091 18.9 0.0 2.2 2 1 0 2 2 2 1 Acid Phosphatase RF-1 PF00472.15 EDO06298.1 - 5.6e-30 103.4 3.5 9.2e-30 102.7 2.4 1.3 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EDO06298.1 - 3.8e-15 55.6 0.2 1.9e-14 53.3 0.0 2.2 2 1 0 2 2 2 1 PCRF domain MIF4G PF02854.14 EDO06299.1 - 2.5e-29 102.2 2.2 3.9e-29 101.5 1.5 1.3 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.10 EDO06299.1 - 8.6e-07 28.0 0.4 0.053 13.0 0.3 2.6 2 0 0 2 2 2 2 Ataxin-2 C-terminal region MA3 PF02847.12 EDO06299.1 - 0.019 14.6 0.7 0.06 13.0 0.1 2.2 2 0 0 2 2 2 0 MA3 domain Bystin PF05291.6 EDO06300.1 - 1.5e-97 326.2 1.5 2.5e-97 325.4 1.0 1.3 1 0 0 1 1 1 1 Bystin Ribosomal_L36e PF01158.13 EDO06301.1 - 1.2e-38 131.0 2.9 1.4e-38 130.7 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF2423 PF10338.4 EDO06302.1 - 0.00027 20.8 0.1 0.00027 20.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) MitMem_reg PF13012.1 EDO06303.1 - 5.6e-29 100.5 0.1 8.8e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EDO06303.1 - 6.7e-26 90.2 0.0 1.4e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CUE PF02845.11 EDO06303.1 - 0.023 14.1 0.1 0.046 13.2 0.1 1.5 1 0 0 1 1 1 0 CUE domain DnaJ PF00226.26 EDO06304.1 - 1.9e-18 65.9 0.6 1.9e-18 65.9 0.4 2.7 2 1 0 2 2 2 1 DnaJ domain Mgr1 PF08602.5 EDO06304.1 - 0.019 13.9 0.8 0.029 13.4 0.6 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF4239 PF14023.1 EDO06304.1 - 0.15 11.3 1.0 0.26 10.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) PSD5 PF07637.6 EDO06304.1 - 0.69 9.9 4.8 9.5 6.3 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1595) Fib_alpha PF08702.5 EDO06304.1 - 4.5 7.3 7.6 3.4 7.7 3.9 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Med26 PF08711.6 EDO06306.1 - 1.8e-05 24.1 0.0 4.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SLBP_RNA_bind PF15247.1 EDO06306.1 - 0.077 12.7 0.2 0.22 11.2 0.2 1.8 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain MS_channel PF00924.13 EDO06308.1 - 1.2e-11 44.3 3.0 2.5e-11 43.3 2.1 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel Rad51 PF08423.6 EDO06309.1 - 1.2e-108 361.8 0.0 1.9e-108 361.2 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EDO06309.1 - 1.5e-10 40.8 0.0 3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EDO06309.1 - 1.9e-08 33.7 0.0 3.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EDO06309.1 - 7.1e-07 28.5 0.1 1.6e-06 27.4 0.1 1.7 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 EDO06309.1 - 0.00018 21.6 1.5 0.00029 20.9 0.3 1.9 3 0 0 3 3 3 1 Helix-hairpin-helix domain AAA_22 PF13401.1 EDO06309.1 - 0.0088 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 EDO06309.1 - 0.048 13.1 0.6 0.11 12.0 0.4 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_pol_A_CTD PF03118.10 EDO06309.1 - 0.062 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain Pescadillo_N PF06732.6 EDO06310.1 - 5.9e-85 284.9 2.3 8.5e-85 284.4 1.6 1.2 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.21 EDO06310.1 - 0.0041 17.2 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain MS_channel PF00924.13 EDO06311.1 - 4.1e-17 62.1 0.9 7.4e-17 61.3 0.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_8 PF13833.1 EDO06311.1 - 0.024 14.2 0.3 0.055 13.0 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.1 EDO06311.1 - 0.12 12.5 0.3 5.9 7.1 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Bromodomain PF00439.20 EDO06312.1 - 8.5e-14 51.2 0.0 2.4e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Bromodomain PI3K_p85B PF02192.11 EDO06313.1 - 0.046 13.1 0.0 1.8 8.0 0.0 2.6 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain Mago_nashi PF02792.9 EDO06314.1 - 3e-67 224.7 0.4 4.1e-67 224.3 0.2 1.1 1 0 0 1 1 1 1 Mago nashi protein Bunya_G2 PF03563.8 EDO06314.1 - 0.054 12.3 2.1 0.089 11.6 1.5 1.4 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 PQQ PF01011.16 EDO06315.1 - 0.046 13.2 0.1 0.47 10.0 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat DUF3639 PF12341.3 EDO06315.1 - 1.6 8.7 3.7 0.71 9.9 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) START PF01852.14 EDO06316.1 - 5.8e-07 29.0 0.2 7.3e-07 28.7 0.1 1.1 1 0 0 1 1 1 1 START domain AMP-binding PF00501.23 EDO06318.1 - 1.7e-89 300.0 0.1 2.1e-89 299.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDO06318.1 - 2.5e-14 53.9 0.1 8.4e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HEAT_EZ PF13513.1 EDO06319.1 - 1e-19 70.4 0.3 5.5e-10 39.4 0.0 7.7 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.1 EDO06319.1 - 3.4e-16 59.2 0.5 1.6e-07 31.5 0.1 6.6 4 3 2 6 6 6 4 HEAT repeats HEAT PF02985.17 EDO06319.1 - 4.3e-13 48.1 11.0 0.024 14.6 0.0 8.7 9 0 0 9 9 9 4 HEAT repeat IBN_N PF03810.14 EDO06319.1 - 9.9e-07 28.5 0.8 0.00018 21.3 0.0 4.1 5 0 0 5 5 5 1 Importin-beta N-terminal domain DUF3437 PF11919.3 EDO06319.1 - 0.0025 17.4 0.2 1.1 9.0 0.1 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) Arm PF00514.18 EDO06319.1 - 0.0075 16.0 7.8 4.7 7.1 0.0 5.3 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 EDO06319.1 - 0.057 13.7 0.2 2 8.8 0.0 3.3 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Anticodon_1 PF08264.8 EDO06319.1 - 0.15 11.8 2.4 0.2 11.3 0.0 2.4 3 0 0 3 3 3 0 Anticodon-binding domain of tRNA Thioredoxin PF00085.15 EDO06320.1 - 1.9e-26 91.7 0.1 2.1e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EDO06320.1 - 2e-07 31.0 0.3 5.1e-06 26.5 0.1 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EDO06320.1 - 4.7e-05 23.5 0.3 0.00047 20.3 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EDO06320.1 - 0.00051 19.8 0.0 0.015 15.0 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin domain Redoxin PF08534.5 EDO06320.1 - 0.0006 19.3 0.1 0.001 18.6 0.1 1.3 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EDO06320.1 - 0.013 15.1 0.2 0.024 14.3 0.1 1.4 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.1 EDO06320.1 - 0.028 13.9 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.1 EDO06320.1 - 0.055 13.5 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.11 EDO06320.1 - 0.071 11.8 0.0 0.071 11.8 0.0 1.1 1 0 0 1 1 1 0 Phosducin Sep15_SelM PF08806.6 EDO06320.1 - 0.13 12.0 0.1 0.22 11.2 0.1 1.5 1 1 0 1 1 1 0 Sep15/SelM redox domain Ribosomal_L28 PF00830.14 EDO06321.1 - 0.00018 21.2 0.4 0.00087 19.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal L28 family STAG PF08514.6 EDO06322.1 - 2.4e-06 27.2 1.2 3.9e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 STAG domain Adaptin_N PF01602.15 EDO06323.1 - 1.1e-74 251.6 0.3 2.6e-74 250.4 0.2 1.5 2 0 0 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.1 EDO06323.1 - 6.8e-05 23.0 0.2 0.86 9.9 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 EDO06323.1 - 0.00024 20.9 2.6 0.004 17.0 0.2 3.1 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 C2 PF00168.25 EDO06324.1 - 2.9e-10 39.8 0.0 0.0078 16.0 0.0 4.1 4 0 0 4 4 4 3 C2 domain DUF4294 PF14127.1 EDO06324.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) F5_F8_type_C PF00754.20 EDO06325.1 - 7e-14 51.7 1.5 8e-09 35.4 0.2 2.7 2 0 0 2 2 2 2 F5/8 type C domain LCCL PF03815.14 EDO06325.1 - 3.6e-12 46.1 0.1 3.6e-12 46.1 0.1 2.6 3 0 0 3 3 3 1 LCCL domain Ricin_B_lectin PF00652.17 EDO06325.1 - 1e-07 32.0 1.2 1.7e-07 31.3 0.1 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Fibrinogen_C PF00147.13 EDO06325.1 - 0.0062 16.1 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Vac_Fusion PF02346.11 EDO06325.1 - 4.9 6.6 5.5 3.9 6.9 0.2 3.1 3 0 0 3 3 3 0 Chordopoxvirus fusion protein RAP PF08373.5 EDO06327.1 - 0.0037 17.0 0.0 0.0099 15.6 0.0 1.7 1 0 0 1 1 1 1 RAP domain Arm PF00514.18 EDO06329.1 - 9.8e-05 22.0 0.1 0.27 11.1 0.0 3.4 2 1 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EDO06329.1 - 0.072 13.3 0.1 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 HEAT repeats HlyIII PF03006.15 EDO06330.1 - 3.1e-15 56.2 15.4 3.9e-15 55.8 10.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Methyltransf_31 PF13847.1 EDO06333.1 - 0.0013 18.3 0.0 0.0013 18.3 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain DUF2304 PF10066.4 EDO06334.1 - 0.028 14.2 0.2 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) RNA_pol_Rpb4 PF03874.11 EDO06334.1 - 0.044 13.7 1.3 1.1 9.2 0.0 3.3 3 1 0 3 3 3 0 RNA polymerase Rpb4 Imm3 PF14425.1 EDO06334.1 - 0.06 13.3 1.7 0.14 12.1 0.2 2.3 2 0 0 2 2 2 0 Immunity protein Imm3 NanE PF04131.9 EDO06334.1 - 0.1 11.5 0.4 0.24 10.3 0.0 1.8 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase QueF_N PF14819.1 EDO06334.1 - 0.13 12.4 0.6 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term NAP PF00956.13 EDO06335.1 - 1e-22 80.4 0.2 1.3e-22 80.1 0.1 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) PMEI PF04043.10 EDO06335.1 - 0.00059 19.7 0.1 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor Baculo_PEP_C PF04513.7 EDO06335.1 - 0.0075 16.1 0.3 0.011 15.5 0.2 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1351 PF07083.6 EDO06335.1 - 0.098 12.2 0.2 0.41 10.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) WD40 PF00400.27 EDO06336.1 - 3.9e-27 93.1 23.9 1.3e-06 28.0 0.6 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EDO06336.1 - 0.025 14.8 0.2 77 3.7 0.0 4.3 5 0 0 5 5 5 0 PQQ-like domain Antig_Caf1 PF09255.5 EDO06336.1 - 0.084 12.7 0.1 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 Caf1 Capsule antigen Hira PF07569.6 EDO06336.1 - 0.086 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split SF-assemblin PF06705.6 EDO06337.1 - 1.4e-31 109.5 28.5 1.9e-31 109.1 19.8 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin Baculo_PEP_C PF04513.7 EDO06337.1 - 0.0021 17.9 12.5 0.073 12.8 2.8 2.5 2 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EDO06337.1 - 0.1 12.3 13.8 0.79 9.5 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2317 PF10079.4 EDO06337.1 - 0.12 10.9 20.4 0.29 9.6 8.1 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2317) NPV_P10 PF05531.7 EDO06337.1 - 0.44 10.8 8.4 0.71 10.1 0.5 3.6 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF310 PF03750.8 EDO06337.1 - 0.59 10.3 11.7 3 8.0 3.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF310) DUF948 PF06103.6 EDO06337.1 - 1.3 8.9 9.9 4.3 7.2 1.0 3.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FAD-SLDH PF12318.3 EDO06337.1 - 2.7 7.6 5.2 2.9 7.5 0.2 2.7 1 1 2 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase FlaC_arch PF05377.6 EDO06337.1 - 4.9 7.1 12.8 0.65 9.9 0.2 4.1 3 2 0 3 3 3 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.8 EDO06337.1 - 5.2 7.8 18.7 10 6.9 3.3 3.6 2 1 1 3 3 3 0 Occludin homology domain DUF4407 PF14362.1 EDO06337.1 - 6.1 5.7 12.3 68 2.2 8.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RWD PF05773.17 EDO06338.1 - 4.1e-14 52.4 0.1 7.8e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 RWD domain CASP_C PF08172.7 EDO06339.1 - 0.041 12.9 0.1 0.071 12.1 0.1 1.4 1 0 0 1 1 1 0 CASP C terminal XPG_I PF00867.13 EDO06341.1 - 3.5e-25 87.8 0.0 1.2e-24 86.1 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EDO06341.1 - 1.7e-16 60.3 0.0 4.3e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EDO06341.1 - 5.8e-05 22.7 0.1 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing zf-CCCH PF00642.19 EDO06342.1 - 9.4e-09 34.7 2.6 9.4e-09 34.7 1.8 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NUFIP1 PF10453.4 EDO06342.1 - 1.6e-07 30.6 0.4 2.8e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH_2 PF14608.1 EDO06342.1 - 0.018 14.9 1.3 0.018 14.9 0.9 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type GAPT PF11770.3 EDO06342.1 - 0.086 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Dpoe2NT PF12213.3 EDO06343.1 - 0.0029 17.5 1.0 1.4 8.8 0.0 3.5 3 0 0 3 3 3 2 DNA polymerases epsilon N terminal Vac14_Fab1_bd PF12755.2 EDO06343.1 - 0.076 13.4 0.1 0.96 9.8 0.0 2.8 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region WD40 PF00400.27 EDO06344.1 - 9.3e-49 161.6 5.4 1.3e-09 37.5 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EDO06344.1 - 9.2e-05 21.3 0.0 0.00015 20.6 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like PQQ PF01011.16 EDO06344.1 - 0.00043 19.6 0.0 1.4 8.5 0.0 3.0 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.1 EDO06344.1 - 0.0037 16.7 0.0 0.092 12.1 0.0 2.6 2 1 1 3 3 3 1 PQQ-like domain DUF3312 PF11768.3 EDO06344.1 - 0.084 11.0 0.0 1.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) PQQ_3 PF13570.1 EDO06344.1 - 0.085 13.1 5.8 15 6.0 0.0 5.0 6 1 2 8 8 8 0 PQQ-like domain AAA PF00004.24 EDO06345.1 - 5.9e-42 142.9 0.0 1.1e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EDO06345.1 - 1e-06 28.7 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDO06345.1 - 6.4e-06 26.2 0.1 0.00013 21.9 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 EDO06345.1 - 7.2e-06 25.7 0.1 0.00018 21.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EDO06345.1 - 1.7e-05 24.0 0.0 3.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EDO06345.1 - 4.9e-05 23.4 0.2 0.0032 17.6 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EDO06345.1 - 0.00031 21.5 0.6 0.00071 20.3 0.0 1.9 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 EDO06345.1 - 0.0005 19.0 0.0 0.00084 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EDO06345.1 - 0.00098 19.2 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 EDO06345.1 - 0.0025 17.2 0.1 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EDO06345.1 - 0.0028 17.3 0.1 0.0087 15.7 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_3 PF07726.6 EDO06345.1 - 0.0032 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EDO06345.1 - 0.0034 16.5 0.1 0.0067 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EDO06345.1 - 0.0035 16.1 0.0 0.0063 15.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EDO06345.1 - 0.0041 16.5 0.3 0.017 14.5 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EDO06345.1 - 0.0056 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO06345.1 - 0.0063 16.8 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Med4 PF10018.4 EDO06345.1 - 0.0094 15.3 1.2 0.027 13.8 0.1 2.1 3 0 0 3 3 3 1 Vitamin-D-receptor interacting Mediator subunit 4 AAA_24 PF13479.1 EDO06345.1 - 0.01 15.4 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EDO06345.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EDO06345.1 - 0.02 14.3 0.0 0.067 12.6 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EDO06345.1 - 0.022 13.8 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 EDO06345.1 - 0.028 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDO06345.1 - 0.035 14.0 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EDO06345.1 - 0.047 12.7 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EDO06345.1 - 0.078 12.6 0.1 0.66 9.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 EDO06345.1 - 0.08 12.9 0.0 0.2 11.6 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 EDO06345.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EDO06345.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 HEAT_EZ PF13513.1 EDO06347.1 - 1.1e-10 41.6 9.1 0.42 11.1 0.0 9.9 9 2 2 11 11 11 3 HEAT-like repeat HEAT PF02985.17 EDO06347.1 - 6e-10 38.3 8.9 0.0011 18.8 0.0 8.4 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 EDO06347.1 - 3.6e-09 36.7 5.0 0.017 15.3 0.0 8.8 7 2 3 10 10 10 2 HEAT repeats CLASP_N PF12348.3 EDO06347.1 - 1.2e-07 31.3 0.1 0.0043 16.4 0.0 5.3 5 0 0 5 5 5 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 EDO06347.1 - 5.5e-07 29.8 3.0 0.35 11.2 0.0 7.1 7 0 0 7 7 7 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 EDO06347.1 - 0.077 12.8 4.8 1.4 8.8 0.0 5.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Got1 PF04178.7 EDO06350.1 - 3.2e-16 59.5 16.0 3.7e-16 59.2 11.1 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family Macoilin PF09726.4 EDO06351.1 - 7.9 4.6 7.6 9 4.4 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein INCENP_ARK-bind PF03941.10 EDO06352.1 - 0.0028 17.4 0.1 0.0052 16.6 0.1 1.5 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region RBFA PF02033.13 EDO06354.1 - 1.8e-06 27.8 0.0 3.3e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Ribosome-binding factor A CBFD_NFYB_HMF PF00808.18 EDO06354.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MMR_HSR1 PF01926.18 EDO06355.1 - 3e-13 49.7 0.0 3.5e-12 46.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EDO06355.1 - 2e-05 23.7 0.0 6.7e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 AIG1 family FeoB_N PF02421.13 EDO06355.1 - 9e-05 21.8 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EDO06355.1 - 0.0023 17.7 0.0 0.061 13.1 0.0 2.5 2 1 0 2 2 2 1 Dynamin family Ribosomal_S16 PF00886.14 EDO06355.1 - 0.034 13.8 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S16 PriCT_1 PF08708.6 EDO06355.1 - 0.062 13.1 0.1 17 5.3 0.0 2.6 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) DUF258 PF03193.11 EDO06355.1 - 0.11 11.6 0.0 0.31 10.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Acetyltransf_1 PF00583.19 EDO06356.1 - 5.1e-08 32.8 0.1 8.2e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EDO06356.1 - 0.00098 18.8 0.1 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EDO06356.1 - 0.045 13.6 0.2 0.056 13.3 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO06356.1 - 0.06 13.4 0.0 0.087 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S10 PF00338.17 EDO06357.1 - 6.4e-27 93.2 0.1 8.9e-27 92.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Chorismate_synt PF01264.16 EDO06357.1 - 0.022 13.2 0.0 0.026 13.0 0.0 1.1 1 0 0 1 1 1 0 Chorismate synthase IMCp PF12314.3 EDO06358.1 - 3.6e-29 100.7 47.8 3.3e-28 97.6 23.9 2.7 1 1 2 3 3 3 2 Inner membrane complex protein MKT1_C PF12246.3 EDO06359.1 - 4.3e-51 173.2 0.0 7.6e-51 172.4 0.0 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EDO06359.1 - 8.4e-21 74.0 0.1 2.8e-20 72.4 0.0 2.0 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EDO06359.1 - 4.1e-11 42.7 0.0 7.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EDO06359.1 - 0.00016 21.8 0.0 0.0004 20.6 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain PLD_C PF12357.3 EDO06359.1 - 0.051 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Phospholipase D C terminal GTP_EFTU PF00009.22 EDO06360.1 - 3.4e-29 101.6 0.0 5.1e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EDO06360.1 - 5.4e-21 74.3 0.0 1.3e-20 73.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EDO06360.1 - 6.8e-19 67.5 0.0 2e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDO06360.1 - 1.7e-08 34.4 0.1 4.7e-08 33.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EDO06360.1 - 2.5e-08 33.6 0.0 4.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 EDO06360.1 - 0.0013 19.1 0.0 0.0035 17.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDO06360.1 - 0.0024 17.8 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Laminin_G_3 PF13385.1 EDO06361.1 - 2e-13 50.8 0.1 7.7e-12 45.7 0.0 2.6 1 1 1 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 EDO06361.1 - 2.6e-05 24.2 0.0 5.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 EDO06361.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain DUF1080 PF06439.6 EDO06361.1 - 0.075 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) Big_5 PF13205.1 EDO06361.1 - 0.15 12.6 0.0 0.98 10.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain Sialidase PF02973.11 EDO06361.1 - 0.16 10.9 0.2 4.8 6.1 0.0 2.6 2 1 0 3 3 3 0 Sialidase, N-terminal domain CLP_protease PF00574.18 EDO06362.1 - 2.2e-65 219.7 0.1 2.7e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Clp protease HSP20 PF00011.16 EDO06363.1 - 5.7e-12 45.4 0.0 1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Peptidase_C48 PF02902.14 EDO06364.1 - 3.5e-36 124.8 3.3 5.5e-36 124.2 0.3 2.0 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF4208 PF13907.1 EDO06364.1 - 0.0085 16.2 0.2 0.017 15.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) AAA_2 PF07724.9 EDO06365.1 - 1.4e-54 184.5 0.0 2.5e-51 173.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EDO06365.1 - 3.6e-26 91.9 0.0 5.8e-14 52.4 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EDO06365.1 - 2.5e-23 81.7 0.7 1.9e-22 78.9 0.5 2.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EDO06365.1 - 2e-17 63.1 0.0 6.2e-12 45.4 0.0 3.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 EDO06365.1 - 3.1e-16 59.0 0.0 5.2e-11 42.3 0.0 3.0 2 0 0 2 2 2 2 Clp amino terminal domain AAA_16 PF13191.1 EDO06365.1 - 2e-10 40.9 0.6 0.0016 18.5 0.0 4.8 3 2 2 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.21 EDO06365.1 - 1.3e-09 37.7 0.0 6.2e-06 25.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 EDO06365.1 - 2.1e-09 37.3 0.0 0.0023 17.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EDO06365.1 - 5.3e-09 36.4 0.3 0.0052 17.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EDO06365.1 - 2.4e-08 34.1 4.1 0.0099 16.0 0.0 4.7 4 1 0 4 4 3 2 AAA domain IstB_IS21 PF01695.12 EDO06365.1 - 3.4e-08 33.0 0.0 0.0098 15.3 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 EDO06365.1 - 8.6e-08 33.0 5.1 0.0035 18.1 0.0 4.8 5 1 0 5 5 5 2 AAA domain Zeta_toxin PF06414.7 EDO06365.1 - 3.9e-05 22.8 0.4 0.01 14.9 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin Mg_chelatase PF01078.16 EDO06365.1 - 5.6e-05 22.4 0.0 0.27 10.3 0.0 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EDO06365.1 - 5.9e-05 22.2 1.7 0.71 8.8 0.0 3.9 2 2 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Torsin PF06309.6 EDO06365.1 - 9.2e-05 22.3 0.0 0.0023 17.8 0.0 2.6 2 0 0 2 2 2 1 Torsin RNA_helicase PF00910.17 EDO06365.1 - 0.00012 22.1 0.3 0.32 11.1 0.0 3.1 4 0 0 4 4 2 1 RNA helicase Arch_ATPase PF01637.13 EDO06365.1 - 0.00017 21.3 9.5 0.54 9.9 0.0 5.0 4 3 2 6 6 6 2 Archaeal ATPase NACHT PF05729.7 EDO06365.1 - 0.0002 21.0 0.0 0.29 10.7 0.0 3.1 2 1 0 2 2 2 1 NACHT domain Bac_DnaA PF00308.13 EDO06365.1 - 0.00045 19.9 0.0 1.1 8.8 0.0 3.9 3 0 0 3 3 3 1 Bacterial dnaA protein ABC_tran PF00005.22 EDO06365.1 - 0.0019 18.4 0.6 0.1 12.9 0.0 3.3 3 1 0 3 3 3 1 ABC transporter AAA_19 PF13245.1 EDO06365.1 - 0.002 17.8 0.0 1.1 9.0 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain NTPase_1 PF03266.10 EDO06365.1 - 0.0022 17.7 2.4 3 7.5 0.0 4.4 4 0 0 4 4 4 1 NTPase MobB PF03205.9 EDO06365.1 - 0.0027 17.4 0.0 0.28 10.8 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EDO06365.1 - 0.0036 16.9 0.0 3.3 7.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EDO06365.1 - 0.004 16.1 0.1 0.02 13.7 0.0 2.4 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 EDO06365.1 - 0.0054 16.2 6.7 0.063 12.6 0.0 4.4 3 2 1 5 5 5 1 AAA-like domain AAA_25 PF13481.1 EDO06365.1 - 0.0059 16.0 0.0 0.83 9.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EDO06365.1 - 0.01 15.4 0.0 1.5 8.4 0.0 2.8 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 EDO06365.1 - 0.013 15.0 0.0 4.5 6.8 0.0 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EDO06365.1 - 0.014 15.3 0.0 2.2 8.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EDO06365.1 - 0.015 15.2 0.0 9.4 6.1 0.0 3.1 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EDO06365.1 - 0.021 14.2 0.0 0.24 10.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EDO06365.1 - 0.023 13.8 0.0 3.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Prominin PF05478.6 EDO06365.1 - 0.036 11.6 1.9 0.053 11.0 0.8 1.6 2 0 0 2 2 2 0 Prominin ResIII PF04851.10 EDO06365.1 - 0.039 13.7 0.9 4.8 6.9 0.0 3.8 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit SRP54 PF00448.17 EDO06365.1 - 0.05 13.0 0.3 4.9 6.5 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF87 PF01935.12 EDO06365.1 - 0.084 12.6 1.9 2.3 7.9 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function DUF87 VESA1_N PF12785.2 EDO06366.1 - 1.6e-52 179.0 1.8 1.8e-52 178.8 1.2 1.0 1 0 0 1 1 1 1 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO06367.1 - 2.4e-222 738.9 22.5 2.4e-222 738.9 15.6 2.5 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO06368.1 - 5.3e-23 81.7 34.5 9.8e-13 47.8 0.0 4.6 2 1 2 4 4 4 3 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO06369.1 - 2.8e-216 718.9 15.9 2.8e-216 718.9 11.0 2.1 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 LXG PF04740.7 EDO06369.1 - 0.0029 17.4 7.3 0.044 13.5 0.2 3.3 4 0 0 4 4 4 2 LXG domain of WXG superfamily MutS_III PF05192.13 EDO06369.1 - 0.03 14.1 0.3 0.08 12.7 0.2 1.7 1 0 0 1 1 1 0 MutS domain III Hydrolase_6 PF13344.1 EDO06369.1 - 0.075 12.9 0.1 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Reo_sigmaC PF04582.7 EDO06369.1 - 0.13 11.4 2.0 0.67 9.0 0.6 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein APG17 PF04108.7 EDO06369.1 - 0.36 9.5 1.2 3.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Autophagy protein Apg17 DHC_N1 PF08385.7 EDO06369.1 - 0.58 8.4 1.0 0.7 8.2 0.0 1.5 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 Mnd1 PF03962.10 EDO06369.1 - 0.59 9.7 4.7 8.3 6.0 0.5 2.4 2 0 0 2 2 2 0 Mnd1 family PEP-utilisers_N PF05524.8 EDO06369.1 - 0.8 9.5 2.8 6.1 6.6 0.1 2.6 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal NPV_P10 PF05531.7 EDO06369.1 - 1.3 9.3 8.3 3.9 7.7 0.4 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ApoLp-III PF07464.6 EDO06369.1 - 2.3 8.2 8.9 3.3 7.7 1.9 2.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) FliD_N PF02465.13 EDO06369.1 - 3.8 7.9 5.2 39 4.7 0.0 3.5 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 N-terminus DUF3486 PF11985.3 EDO06369.1 - 5.3 7.0 8.2 16 5.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) DUF4175 PF13779.1 EDO06369.1 - 7.3 4.1 6.2 8.7 3.9 2.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4175) F-box-like_2 PF13013.1 EDO06370.1 - 4.5e-06 26.3 0.3 0.0063 16.2 0.0 2.4 2 0 0 2 2 2 2 F-box-like domain SUKH-4 PF14435.1 EDO06370.1 - 0.0075 16.0 0.2 3.5 7.3 0.0 3.0 1 1 1 3 3 3 2 SUKH-4 immunity protein Enterotoxin_ST PF02048.11 EDO06372.1 - 0.4 10.9 2.2 0.8 10.0 1.5 1.4 1 0 0 1 1 1 0 Heat-stable enterotoxin ST MFS_1 PF07690.11 EDO06373.1 - 1.8e-16 59.7 22.0 1.8e-16 59.7 15.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily VESA1_N PF12785.2 EDO06374.1 - 0.00036 19.6 46.6 0.0022 17.0 21.5 3.7 3 1 0 3 3 3 1 Variant erythrocyte surface antigen-1 Virul_fac_BrkB PF03631.10 EDO06375.1 - 4.1 6.6 24.2 0.71 9.1 4.1 3.6 4 0 0 4 4 4 0 Virulence factor BrkB F-box-like_2 PF13013.1 EDO06377.1 - 0.0047 16.6 0.1 1.4 8.6 0.0 2.6 1 1 2 3 3 3 2 F-box-like domain SURF1 PF02104.10 EDO06377.1 - 0.024 14.4 0.0 6.7 6.4 0.0 2.1 2 0 0 2 2 2 0 SURF1 family DUF2770 PF10968.3 EDO06377.1 - 0.17 11.5 2.4 0.54 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2770) AP2 PF00847.15 EDO06378.1 - 6.6e-11 42.1 0.1 2.1e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 AP2 domain Ribosomal_L7Ae PF01248.21 EDO06380.1 - 7.4e-16 57.4 0.1 7.4e-16 57.4 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EDO06380.1 - 1.2e-05 25.2 0.7 1.5e-05 24.8 0.5 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 AAA_18 PF13238.1 EDO06380.1 - 0.077 13.3 0.1 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ran_BP1 PF00638.13 EDO06381.1 - 7.1e-40 135.8 1.8 1.2e-39 135.1 1.2 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EDO06381.1 - 0.01 15.5 0.8 0.098 12.3 0.5 2.2 1 1 0 1 1 1 0 WH1 domain MMS1_N PF10433.4 EDO06382.1 - 1e-87 294.4 0.0 1.5e-87 293.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EDO06382.1 - 7.8e-80 268.3 0.1 3e-78 263.1 0.0 3.2 4 0 0 4 4 4 1 CPSF A subunit region CPW_WPC PF09717.5 EDO06383.1 - 6.4e-72 238.0 45.9 3.9e-15 56.2 3.2 7.7 8 0 0 8 8 8 7 Plasmodium falciparum domain of unknown function (CPW_WPC) PSII_Pbs27 PF13326.1 EDO06383.1 - 0.21 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Photosystem II Pbs27 CAS_CSE1 PF03378.10 EDO06384.1 - 2.4e-50 171.1 2.3 6.5e-50 169.6 1.3 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EDO06384.1 - 1.4e-43 148.8 0.5 4.2e-43 147.3 0.3 1.9 2 0 0 2 2 2 1 Cse1 Proteasom_PSMB PF10508.4 EDO06384.1 - 0.00034 19.0 1.3 0.00077 17.8 0.2 2.1 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit IBN_N PF03810.14 EDO06384.1 - 0.0068 16.2 0.2 0.34 10.8 0.0 3.5 3 1 0 3 3 3 1 Importin-beta N-terminal domain Arf PF00025.16 EDO06385.1 - 7e-57 191.4 0.0 8.2e-57 191.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EDO06385.1 - 1e-09 37.6 0.1 7.2e-07 28.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EDO06385.1 - 4.8e-08 32.9 0.0 6.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDO06385.1 - 6.1e-08 33.1 0.0 8.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EDO06385.1 - 1.8e-07 30.6 0.0 2.3e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 EDO06385.1 - 1.6e-06 27.4 0.0 2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EDO06385.1 - 1e-05 24.8 0.0 1.3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO06385.1 - 0.00011 21.6 0.0 0.0029 17.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF2582 PF10771.4 EDO06385.1 - 0.0036 17.1 0.5 0.01 15.6 0.1 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2582) PduV-EutP PF10662.4 EDO06385.1 - 0.017 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EDO06385.1 - 0.023 14.6 0.0 0.084 12.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EDO06385.1 - 0.027 14.6 0.0 0.064 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EDO06385.1 - 0.03 13.9 0.1 0.75 9.4 0.1 2.2 1 1 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 EDO06385.1 - 0.058 12.7 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Band_7 PF01145.20 EDO06387.1 - 1.6e-06 28.1 0.3 2.1e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Maf1 PF09174.5 EDO06388.1 - 1.3e-29 103.2 5.2 1.6e-29 103.0 3.6 1.1 1 0 0 1 1 1 1 Maf1 regulator CRAL_TRIO PF00650.15 EDO06389.1 - 1.3e-27 96.2 0.2 2.2e-27 95.5 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDO06389.1 - 4.9e-05 23.3 0.5 0.00014 21.9 0.4 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain LETM1 PF07766.8 EDO06390.1 - 2.2e-62 210.5 11.8 2.2e-62 210.5 8.2 1.8 2 0 0 2 2 2 1 LETM1-like protein DUF2340 PF10209.4 EDO06390.1 - 0.0072 16.4 0.7 0.028 14.5 0.5 2.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Memo PF01875.12 EDO06391.1 - 1.9e-48 164.7 1.5 7.1e-44 149.7 0.0 2.8 1 1 2 3 3 3 2 Memo-like protein Patched PF02460.13 EDO06391.1 - 0.034 12.0 0.0 0.041 11.7 0.0 1.1 1 0 0 1 1 1 0 Patched family Pkinase PF00069.20 EDO06393.1 - 7.1e-73 244.9 0.0 1.6e-72 243.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO06393.1 - 1.1e-36 126.2 0.0 2e-36 125.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO06393.1 - 7.2e-07 28.4 0.0 1.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO06393.1 - 0.0024 17.6 0.3 0.36 10.5 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family CITED PF04487.7 EDO06393.1 - 0.093 12.9 0.2 0.62 10.2 0.0 2.1 2 0 0 2 2 2 0 CITED Mito_carr PF00153.22 EDO06394.1 - 1.6e-34 117.4 2.3 4.6e-13 48.6 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF3561 PF12084.3 EDO06394.1 - 0.17 11.7 1.8 0.39 10.5 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3561) BTB_2 PF02214.17 EDO06395.1 - 7.6e-14 51.6 0.3 4.4e-13 49.2 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain SecA_DEAD PF07517.9 EDO06395.1 - 0.047 12.9 0.1 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain TH1 PF04858.8 EDO06396.1 - 2.7e-13 48.9 4.9 5.6e-06 24.7 1.3 3.0 3 0 0 3 3 3 2 TH1 protein INTS5_N PF14837.1 EDO06396.1 - 0.034 13.5 0.2 0.5 9.7 0.0 2.7 3 0 0 3 3 3 0 Integrator complex subunit 5 N-terminus FH2 PF02181.18 EDO06397.1 - 1.1e-66 225.2 0.0 1.9e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain TPR_12 PF13424.1 EDO06397.1 - 1.8e-12 46.9 0.4 2.4e-06 27.3 0.0 4.7 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 EDO06397.1 - 3.4e-06 26.7 0.0 0.047 13.6 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDO06397.1 - 0.0011 18.6 0.3 0.042 13.5 0.0 3.3 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 EDO06397.1 - 0.04 13.5 0.5 1.7 8.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SpoVR PF04293.8 EDO06397.1 - 0.081 11.2 0.0 0.14 10.5 0.0 1.3 1 0 0 1 1 1 0 SpoVR like protein CPW_WPC PF09717.5 EDO06398.1 - 9.3e-35 119.0 17.2 1.4e-17 64.0 1.0 2.2 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) CSTF2_hinge PF14327.1 EDO06399.1 - 3.5e-19 68.6 0.4 7.4e-19 67.6 0.3 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 Peptidase_M17 PF00883.16 EDO06400.1 - 1.5e-109 365.7 0.2 1.8e-109 365.3 0.2 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF2156 PF09924.4 EDO06400.1 - 0.14 10.9 0.0 0.27 9.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) DUF826 PF05696.6 EDO06401.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF826) Erp_C PF06780.6 EDO06401.1 - 0.22 11.3 0.0 0.57 10.0 0.0 1.7 1 0 0 1 1 1 0 Erp protein C-terminus DEAD PF00270.24 EDO06402.1 - 4.8e-44 149.8 0.0 3.2e-43 147.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO06402.1 - 7.7e-27 92.9 0.0 2.2e-26 91.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO06402.1 - 0.00013 21.8 0.0 0.00045 20.1 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EDO06402.1 - 0.037 13.9 0.0 0.079 12.9 0.0 1.6 2 0 0 2 2 2 0 Helicase C-terminal domain SPOC PF07744.8 EDO06403.1 - 9.7e-14 51.8 0.0 1.4e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 SPOC domain Methyltransf_26 PF13659.1 EDO06404.1 - 5.1e-10 39.3 0.0 8e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDO06404.1 - 2.1e-06 27.2 0.5 3e-05 23.4 0.4 2.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EDO06404.1 - 0.00012 21.7 0.0 0.00021 20.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO06404.1 - 0.0022 18.3 0.0 0.007 16.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.1 EDO06404.1 - 0.014 16.1 0.0 0.025 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EDO06404.1 - 0.019 15.5 0.0 0.046 14.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EDO06404.1 - 0.027 13.8 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Met_10 PF02475.11 EDO06404.1 - 0.038 13.5 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.14 EDO06404.1 - 0.042 13.3 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EDO06404.1 - 0.3 10.1 0.8 2.8 6.9 0.5 2.0 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Baculo_PEP_C PF04513.7 EDO06406.1 - 0.0073 16.1 0.2 0.46 10.3 0.1 3.0 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus EzrA PF06160.7 EDO06406.1 - 0.4 8.7 0.2 0.65 8.1 0.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA COX4 PF02936.9 EDO06408.1 - 0.0029 17.3 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF896 PF05979.7 EDO06410.1 - 0.099 12.2 1.2 0.3 10.7 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) RRM_1 PF00076.17 EDO06411.1 - 0.00055 19.5 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S17 PF00366.15 EDO06412.1 - 4.1e-27 94.0 0.3 4.1e-27 94.0 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 L51_S25_CI-B8 PF05047.11 EDO06413.1 - 7.9e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LysR_substrate PF03466.15 EDO06413.1 - 0.047 12.7 0.1 0.078 12.0 0.1 1.3 1 0 0 1 1 1 0 LysR substrate binding domain DUF1754 PF08555.5 EDO06415.1 - 0.015 15.8 0.4 0.015 15.8 0.2 1.8 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) HA2 PF04408.18 EDO06416.1 - 2.5e-22 78.8 0.9 4.6e-22 77.9 0.6 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDO06416.1 - 3e-16 59.2 0.0 5.3e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EDO06416.1 - 1.8e-12 46.9 0.0 4.2e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO06416.1 - 1.8e-08 34.0 0.5 5.4e-08 32.5 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDO06416.1 - 3.3e-07 30.5 0.1 9.6e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EDO06416.1 - 0.00031 21.0 0.0 0.00082 19.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EDO06416.1 - 0.00041 19.8 0.1 0.001 18.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2075 PF09848.4 EDO06416.1 - 0.0015 17.6 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 EDO06416.1 - 0.0015 18.1 0.0 0.0062 16.1 0.0 2.0 3 0 0 3 3 2 1 Helicase T2SE PF00437.15 EDO06416.1 - 0.0033 16.3 0.1 0.007 15.3 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EDO06416.1 - 0.0072 16.0 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EDO06416.1 - 0.0084 16.0 0.1 0.062 13.1 0.1 2.4 2 1 0 2 2 1 1 AAA domain UPF0079 PF02367.12 EDO06416.1 - 0.0085 15.7 0.0 0.03 13.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 EDO06416.1 - 0.009 15.2 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NACHT PF05729.7 EDO06416.1 - 0.0097 15.5 0.0 0.031 13.9 0.0 2.0 2 1 0 2 2 2 1 NACHT domain Flavi_DEAD PF07652.9 EDO06416.1 - 0.0098 15.6 0.1 0.029 14.1 0.0 1.8 2 0 0 2 2 1 1 Flavivirus DEAD domain cobW PF02492.14 EDO06416.1 - 0.011 15.1 0.1 0.03 13.7 0.1 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EDO06416.1 - 0.015 15.6 0.4 0.11 12.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EDO06416.1 - 0.017 14.8 0.2 0.082 12.5 0.0 2.2 3 0 0 3 3 2 0 Archaeal ATPase NB-ARC PF00931.17 EDO06416.1 - 0.019 13.8 0.1 0.064 12.0 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 EDO06416.1 - 0.041 13.2 0.0 0.092 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 EDO06416.1 - 0.042 12.7 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EDO06416.1 - 0.049 13.6 0.4 0.19 11.6 0.3 2.0 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EDO06416.1 - 0.05 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 EDO06416.1 - 0.054 12.9 0.1 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain ResIII PF04851.10 EDO06416.1 - 0.077 12.8 0.0 6.1 6.6 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EDO06416.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EDO06416.1 - 0.13 12.0 0.6 2.5 7.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 EDO06416.1 - 0.15 11.8 0.8 0.66 9.7 0.6 2.1 1 1 0 1 1 1 0 Dynamin family IPP-2 PF04979.9 EDO06418.1 - 7.6e-07 29.4 7.5 7e-06 26.3 0.3 2.3 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Prosystemin PF07376.6 EDO06418.1 - 0.066 12.5 3.3 0.11 11.8 2.3 1.4 1 1 0 1 1 1 0 Prosystemin DLD PF14878.1 EDO06418.1 - 0.26 11.3 2.0 1.7 8.8 1.0 2.1 1 1 1 2 2 2 0 Death-like domain of SPT6 IR1-M PF12185.3 EDO06418.1 - 1.5 8.6 3.9 0.72 9.6 0.1 2.2 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain Spt5_N PF11942.3 EDO06418.1 - 4.1 8.0 12.0 0.52 10.9 4.6 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Longin PF13774.1 EDO06419.1 - 4e-20 71.1 0.2 6.5e-20 70.4 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EDO06419.1 - 3.5e-07 29.7 0.5 1e-06 28.2 0.3 1.8 1 0 0 1 1 1 1 Synaptobrevin TcpA PF05946.7 EDO06419.1 - 0.07 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA Cpn60_TCP1 PF00118.19 EDO06420.1 - 9.3e-145 482.9 4.4 1.1e-144 482.7 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family APP_N PF02177.11 EDO06420.1 - 0.068 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding UQ_con PF00179.21 EDO06421.1 - 4.2e-47 159.1 0.1 4.8e-47 158.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDO06421.1 - 0.033 14.0 0.3 0.045 13.6 0.2 1.4 1 1 0 1 1 1 0 RWD domain Exo_endo_phos PF03372.18 EDO06422.1 - 1.4e-14 54.6 0.1 2e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DEAD PF00270.24 EDO06423.1 - 9.8e-17 60.9 0.4 2.8e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO06423.1 - 3.1e-13 49.3 0.2 6.3e-12 45.1 0.0 2.7 1 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF747 PF05346.6 EDO06424.1 - 6.7e-122 406.6 17.5 8.5e-122 406.3 12.1 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DNA_pol_E_B PF04042.11 EDO06425.1 - 3e-21 75.6 0.1 3.4e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B RecA PF00154.16 EDO06427.1 - 0.013 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_16 PF13191.1 EDO06427.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain CTDII PF01556.13 EDO06428.1 - 2.2e-17 62.7 4.6 1.9e-08 34.0 0.1 3.9 4 1 0 4 4 4 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EDO06428.1 - 6.6e-12 45.3 15.8 1.2e-11 44.4 10.9 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 EDO06428.1 - 8.9e-09 34.9 0.8 4.7e-08 32.6 0.4 2.3 2 1 0 2 2 2 1 DnaJ domain TBCA PF02970.11 EDO06428.1 - 0.38 10.8 2.7 0.31 11.1 0.1 2.0 2 0 0 2 2 2 0 Tubulin binding cofactor A zf-DHHC PF01529.15 EDO06428.1 - 0.53 9.6 9.6 4 6.8 0.5 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase Fis1_TPR_C PF14853.1 EDO06429.1 - 7e-12 45.0 0.6 7e-12 45.0 0.4 2.1 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 EDO06429.1 - 1.5e-07 30.7 0.9 0.00013 21.5 0.1 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDO06429.1 - 6.6e-07 28.8 0.5 2.6e-06 26.9 0.1 2.1 1 1 0 1 1 1 1 TPR repeat Fis1_TPR_N PF14852.1 EDO06429.1 - 3.1e-06 26.3 0.0 5.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_6 PF13174.1 EDO06429.1 - 2.6e-05 24.3 0.9 0.0017 18.6 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDO06429.1 - 8.7e-05 22.7 1.0 0.00017 21.8 0.1 1.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO06429.1 - 0.0004 20.9 2.7 0.021 15.5 0.1 2.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO06429.1 - 0.0005 19.9 1.9 0.0026 17.6 0.6 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDO06429.1 - 0.00053 20.3 2.6 0.011 16.2 0.2 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDO06429.1 - 0.0017 17.9 1.0 0.0091 15.5 0.0 2.7 3 1 1 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EDO06429.1 - 0.0018 18.3 0.7 0.0035 17.4 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EDO06429.1 - 0.082 12.7 2.4 0.17 11.7 1.2 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDO06429.1 - 0.41 10.5 2.9 2.4 8.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L39 PF00832.15 EDO06430.1 - 1.1e-21 75.9 12.2 1.3e-21 75.7 8.5 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein DUF2439 PF10382.4 EDO06432.1 - 1.9e-08 34.4 0.1 5e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Ribosomal_L9_N PF01281.14 EDO06434.1 - 7.4e-16 57.1 0.0 1.6e-15 56.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain PUL PF08324.6 EDO06435.1 - 6.9e-14 51.2 0.9 1.2e-13 50.4 0.6 1.4 1 1 0 1 1 1 1 PUL domain WD40 PF00400.27 EDO06436.1 - 9.9e-24 82.3 11.5 2e-06 27.4 0.2 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.1 EDO06436.1 - 0.09 13.0 0.3 79 3.7 0.0 3.9 2 1 2 4 4 4 0 PQQ-like domain IGPS PF00218.16 EDO06437.1 - 7e-23 80.9 0.0 1.1e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase NMO PF03060.10 EDO06437.1 - 0.0011 18.2 0.8 0.06 12.4 0.1 3.0 3 0 0 3 3 3 1 Nitronate monooxygenase FMN_dh PF01070.13 EDO06437.1 - 0.02 13.7 1.1 0.091 11.5 0.4 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase His_biosynth PF00977.16 EDO06437.1 - 0.028 13.6 0.1 0.067 12.4 0.0 1.7 1 0 0 1 1 1 0 Histidine biosynthesis protein QRPTase_C PF01729.14 EDO06437.1 - 0.039 13.4 0.1 0.2 11.1 0.0 2.1 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF3427 PF11907.3 EDO06437.1 - 0.15 10.9 4.7 0.38 9.6 2.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3427) HATPase_c_5 PF14501.1 EDO06437.1 - 0.36 10.5 3.3 1.6 8.4 0.3 2.6 3 0 0 3 3 3 0 GHKL domain DUF900 PF05990.7 EDO06439.1 - 2.3e-13 50.0 0.0 6.1e-12 45.3 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) NifQ PF04891.7 EDO06439.1 - 0.48 10.5 1.2 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 NifQ RRM_1 PF00076.17 EDO06441.1 - 2.1e-18 65.7 0.0 3.4e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06441.1 - 4.9e-12 45.6 0.0 7.6e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06441.1 - 0.00019 21.1 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EDO06441.1 - 0.067 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain MDH PF02315.11 EDO06441.1 - 0.068 13.1 0.4 0.39 10.6 0.1 2.1 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit HEAT PF02985.17 EDO06442.1 - 0.0069 16.3 0.6 3.3 8.0 0.0 3.8 3 0 0 3 3 3 2 HEAT repeat zf-MIZ PF02891.15 EDO06443.1 - 7.3e-19 67.0 3.8 7.3e-19 67.0 2.6 1.9 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EDO06443.1 - 3.3e-05 23.3 1.8 7.2e-05 22.2 1.3 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 EDO06443.1 - 0.081 12.6 17.1 0.11 12.1 5.1 2.5 2 0 0 2 2 2 0 PHD-finger PINIT PF14324.1 EDO06443.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 PINIT domain M16C_assoc PF08367.6 EDO06444.1 - 7.7e-32 110.0 8.0 2.4e-31 108.4 3.7 2.6 2 1 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EDO06444.1 - 1.6e-19 70.2 0.0 5e-14 52.3 0.0 3.4 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EDO06444.1 - 7e-10 38.8 0.0 4.1e-08 33.1 0.0 3.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Ion_trans_2 PF07885.11 EDO06445.1 - 1.1e-10 41.0 2.8 4.5e-10 39.1 1.7 2.1 2 0 0 2 2 2 1 Ion channel BK_channel_a PF03493.13 EDO06445.1 - 1.8e-06 27.8 0.5 0.00012 22.0 0.1 3.2 3 0 0 3 3 3 1 Calcium-activated BK potassium channel alpha subunit SNF2_N PF00176.18 EDO06446.1 - 6.4e-65 218.8 0.0 1e-64 218.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO06446.1 - 1.7e-13 50.2 0.0 2.2e-12 46.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO06446.1 - 8.5e-05 22.4 1.0 0.0005 19.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA PF00004.24 EDO06447.1 - 7.1e-45 152.4 0.1 2.5e-44 150.6 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO06447.1 - 1e-08 34.9 0.1 3.9e-08 33.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDO06447.1 - 1.9e-07 31.1 0.0 6.4e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EDO06447.1 - 4.1e-06 26.9 0.7 0.00087 19.4 0.5 2.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO06447.1 - 7.4e-06 26.0 0.1 2.9e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EDO06447.1 - 2.4e-05 24.6 0.1 0.0039 17.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDO06447.1 - 3.2e-05 23.0 0.0 7.8e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EDO06447.1 - 3.9e-05 22.7 0.0 0.00011 21.2 0.0 1.8 2 1 0 2 2 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EDO06447.1 - 5.4e-05 23.9 0.1 0.0002 22.1 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EDO06447.1 - 0.00016 21.7 0.0 0.00038 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO06447.1 - 0.00031 20.4 0.2 0.00082 19.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EDO06447.1 - 0.001 18.9 0.1 0.0062 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EDO06447.1 - 0.001 19.1 0.0 0.0033 17.5 0.0 1.9 2 0 0 2 2 1 1 RNA helicase Mg_chelatase PF01078.16 EDO06447.1 - 0.0013 17.9 0.5 0.004 16.3 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EDO06447.1 - 0.0013 18.1 1.2 0.0022 17.4 0.1 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.7 EDO06447.1 - 0.0015 18.1 0.4 0.085 12.5 0.1 2.6 3 0 0 3 3 2 1 NACHT domain AAA_25 PF13481.1 EDO06447.1 - 0.002 17.5 0.7 0.016 14.5 0.1 2.2 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 EDO06447.1 - 0.0021 16.8 0.2 0.011 14.4 0.0 2.2 2 1 1 3 3 3 1 TIP49 C-terminus AAA_33 PF13671.1 EDO06447.1 - 0.0024 17.7 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EDO06447.1 - 0.0036 16.9 0.1 0.0077 15.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EDO06447.1 - 0.0037 16.9 0.0 0.036 13.7 0.0 2.3 2 0 0 2 2 2 1 NTPase Zeta_toxin PF06414.7 EDO06447.1 - 0.0037 16.3 0.0 0.007 15.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EDO06447.1 - 0.0037 16.7 0.2 0.1 12.0 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 EDO06447.1 - 0.0072 15.9 0.0 0.021 14.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prefoldin_2 PF01920.15 EDO06447.1 - 0.0088 15.7 2.0 0.018 14.7 1.4 1.5 1 0 0 1 1 1 1 Prefoldin subunit UPF0079 PF02367.12 EDO06447.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 EDO06447.1 - 0.018 13.9 0.1 0.049 12.5 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EDO06447.1 - 0.022 14.8 0.0 0.064 13.3 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain GrpE PF01025.14 EDO06447.1 - 0.022 14.2 3.5 0.026 14.0 0.2 2.3 3 0 0 3 3 2 0 GrpE AAA_11 PF13086.1 EDO06447.1 - 0.049 13.2 0.2 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EDO06447.1 - 0.085 11.6 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EDO06447.1 - 0.09 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain IPT PF01745.11 EDO06447.1 - 0.092 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase DUF1664 PF07889.7 EDO06447.1 - 0.12 12.1 0.4 0.24 11.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) KaiC PF06745.8 EDO06447.1 - 0.13 11.3 0.8 1.2 8.2 0.0 2.5 3 0 0 3 3 3 0 KaiC ADIP PF11559.3 EDO06447.1 - 0.18 11.6 4.0 0.38 10.6 2.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding AAA_23 PF13476.1 EDO06447.1 - 0.3 11.4 3.3 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain YycI PF09648.5 EDO06448.1 - 0.02 14.3 1.5 0.03 13.7 1.0 1.2 1 0 0 1 1 1 0 YycH protein Adenylsucc_synt PF00709.16 EDO06449.1 - 2.3e-152 507.5 0.0 2.6e-152 507.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase RRM_1 PF00076.17 EDO06450.1 - 1.1e-33 114.6 2.6 7.1e-19 67.2 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06450.1 - 1.5e-26 92.1 0.4 2.7e-10 40.0 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06450.1 - 5e-21 74.2 0.2 1.7e-05 24.5 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 EDO06450.1 - 0.023 14.6 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Smg-4/UPF3 family AhpC-TSA PF00578.16 EDO06451.1 - 9.5e-37 125.4 0.0 1.6e-36 124.7 0.0 1.3 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EDO06451.1 - 2.1e-16 59.7 0.0 2.6e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EDO06451.1 - 6.8e-13 48.0 0.1 1.4e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin GN3L_Grn1 PF08701.6 EDO06452.1 - 7.1e-09 35.4 14.7 7.1e-09 35.4 10.2 1.4 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase DUF148 PF02520.12 EDO06452.1 - 0.074 12.8 0.4 0.074 12.8 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF148 LexA_DNA_bind PF01726.11 EDO06452.1 - 0.08 12.5 1.1 0.17 11.4 0.3 1.8 2 0 0 2 2 2 0 LexA DNA binding domain DUF2786 PF10979.3 EDO06452.1 - 1.7 8.4 5.5 7.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) VCBS PF13517.1 EDO06453.1 - 3.1e-26 91.4 5.9 2.2e-08 34.3 0.0 6.6 5 2 3 8 8 8 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EDO06453.1 - 9e-23 79.3 12.5 0.00028 20.4 0.0 7.3 7 0 0 7 7 7 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 EDO06453.1 - 2.3e-07 30.4 2.5 0.7 9.3 0.0 5.1 4 2 2 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region Dickkopf_N PF04706.7 EDO06453.1 - 7.9 6.7 7.7 19 5.5 0.3 2.4 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Med2 PF11214.3 EDO06455.1 - 0.0071 16.3 0.3 0.015 15.2 0.2 1.6 1 0 0 1 1 1 1 Mediator complex subunit 2 FEZ PF07763.8 EDO06455.1 - 0.016 14.9 2.3 0.52 9.9 0.8 2.2 2 0 0 2 2 2 0 FEZ-like protein PUA PF01472.15 EDO06456.1 - 1.6e-16 59.8 0.0 2.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 PUA domain EAP30 PF04157.11 EDO06457.1 - 5.8e-47 159.7 0.0 6.8e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family HTH_IclR PF09339.5 EDO06457.1 - 0.015 14.8 0.0 0.039 13.5 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain Ribosomal_L16 PF00252.13 EDO06458.1 - 5.8e-17 61.6 0.0 7.4e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CTP_transf_1 PF01148.15 EDO06459.1 - 9e-56 189.3 34.5 1e-54 185.9 23.9 2.0 1 1 0 1 1 1 1 Cytidylyltransferase family Fer2 PF00111.22 EDO06460.1 - 3.2e-17 62.0 3.8 4.6e-17 61.5 2.6 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Ribosomal_S19 PF00203.16 EDO06461.1 - 1.1e-29 101.8 0.3 1.6e-29 101.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Ctr PF04145.10 EDO06462.1 - 2.8e-19 69.5 20.7 2.9e-14 53.3 0.8 2.3 1 1 1 2 2 2 2 Ctr copper transporter family PRA1 PF03208.14 EDO06462.1 - 0.24 10.7 9.0 0.53 9.6 6.2 1.5 1 0 0 1 1 1 0 PRA1 family protein DUF4212 PF13937.1 EDO06464.1 - 0.061 13.3 0.2 0.061 13.3 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4212) DUF4014 PF13198.1 EDO06464.1 - 0.15 12.4 1.3 1.8 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) CBF PF03914.12 EDO06465.1 - 3.8e-28 98.0 0.5 3.8e-28 98.0 0.4 2.2 2 1 0 2 2 2 1 CBF/Mak21 family NOA36 PF06524.7 EDO06465.1 - 9.7 5.3 9.7 17 4.5 6.7 1.3 1 0 0 1 1 1 0 NOA36 protein SPAN-X PF07458.7 EDO06466.1 - 0.5 10.6 7.3 0.38 11.0 1.6 2.6 1 1 0 2 2 2 0 Sperm protein associated with nucleus, mapped to X chromosome MCM PF00493.18 EDO06468.1 - 3.6e-122 407.2 0.0 5.1e-122 406.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDO06468.1 - 3.3e-11 43.7 0.0 8.4e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDO06468.1 - 9.6e-06 24.8 0.0 7.1e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDO06468.1 - 0.00075 19.2 0.0 0.0025 17.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDO06468.1 - 0.0071 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RRM_1 PF00076.17 EDO06469.1 - 0.00064 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06469.1 - 0.0065 16.4 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GAGA_bind PF06217.7 EDO06469.1 - 0.039 13.9 4.7 0.07 13.0 3.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Nup88 PF10168.4 EDO06469.1 - 1 7.1 4.2 1.4 6.6 2.9 1.1 1 0 0 1 1 1 0 Nuclear pore component UCH PF00443.24 EDO06470.1 - 1.9e-31 109.1 0.0 2.7e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EDO06470.1 - 8.8e-11 41.7 2.2 8.8e-11 41.7 1.5 1.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EDO06470.1 - 7.6e-07 28.8 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EPL1 PF10513.4 EDO06471.1 - 3.8e-06 27.2 0.1 6.7e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Enhancer of polycomb-like DUF3776 PF12618.3 EDO06472.1 - 0.0023 18.4 2.5 0.0049 17.4 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3776) DMPK_coil PF08826.5 EDO06472.1 - 0.024 14.5 1.1 0.045 13.6 0.2 1.8 1 1 1 2 2 2 0 DMPK coiled coil domain like OmpH PF03938.9 EDO06472.1 - 0.12 12.3 2.2 0.12 12.2 1.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Dendrin PF15498.1 EDO06472.1 - 0.15 10.4 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin TMF_TATA_bd PF12325.3 EDO06472.1 - 1.2 8.9 7.7 2.3 7.9 5.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EDO06472.1 - 5.5 6.5 7.0 7.7 6.0 4.8 1.2 1 0 0 1 1 1 0 IncA protein CTP_transf_2 PF01467.21 EDO06474.1 - 8.2e-28 97.4 0.4 7.9e-15 55.2 0.0 2.8 2 1 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 EDO06474.1 - 0.0022 17.6 3.8 1.1 8.8 0.2 3.2 4 0 0 4 4 4 2 FAD synthetase HTH_16 PF12645.2 EDO06474.1 - 0.0071 16.2 0.2 1.7 8.6 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain WW PF00397.21 EDO06475.1 - 1.5e-16 59.8 18.2 2e-09 37.1 2.2 3.6 3 0 0 3 3 3 2 WW domain FF PF01846.14 EDO06475.1 - 2.1e-12 46.7 3.0 3e-05 23.8 0.4 4.5 5 0 0 5 5 5 2 FF domain SNAP PF14938.1 EDO06476.1 - 5.1e-75 252.2 12.7 6.2e-75 251.9 8.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 EDO06476.1 - 8.8e-09 34.5 9.9 0.023 14.4 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDO06476.1 - 1.1e-06 28.4 15.9 0.0054 16.6 0.3 4.0 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO06476.1 - 3.2e-05 23.5 16.3 0.022 14.6 2.5 5.6 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDO06476.1 - 0.00021 20.8 20.7 0.13 11.9 0.9 4.9 1 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.1 EDO06476.1 - 0.00046 20.5 8.9 1.9 9.3 0.1 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.2 EDO06476.1 - 0.0013 17.5 3.0 0.0022 16.7 2.0 1.4 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_1 PF00515.23 EDO06476.1 - 0.0028 17.1 19.8 0.22 11.2 2.8 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO06476.1 - 0.087 12.6 10.3 1.4 8.8 1.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EDO06476.1 - 0.31 10.4 4.8 0.76 9.2 1.5 2.4 2 1 0 2 2 2 0 Foie gras liver health family 1 Clathrin PF00637.15 EDO06476.1 - 0.88 9.1 5.5 4.1 6.9 0.3 3.4 2 1 1 4 4 4 0 Region in Clathrin and VPS TPR_19 PF14559.1 EDO06476.1 - 1.1 9.6 11.3 0.61 10.4 0.4 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF1079 PF06435.6 EDO06476.1 - 2 8.4 7.4 7.8 6.5 0.1 3.6 3 0 0 3 3 3 0 Repeat of unknown function (DUF1079) TPR_6 PF13174.1 EDO06476.1 - 3.1 8.4 11.5 32 5.2 0.6 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 EDO06476.1 - 3.3 7.6 11.9 23 4.9 0.2 4.2 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 EDO06476.1 - 5.1 7.5 6.6 3.2 8.1 0.4 3.7 4 1 1 5 5 5 0 Tetratricopeptide repeat CDP-OH_P_transf PF01066.16 EDO06477.1 - 1.7e-14 53.8 6.1 3.1e-14 53.1 4.2 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase GCD14 PF08704.5 EDO06478.1 - 8.6e-62 208.8 0.4 8.3e-61 205.6 0.0 1.9 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EDO06478.1 - 1.2e-08 34.6 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EDO06478.1 - 5.7e-06 25.5 0.0 8.2e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EDO06478.1 - 5.4e-05 23.7 0.0 9.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDO06478.1 - 0.0012 18.4 0.1 0.0053 16.3 0.0 1.9 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 EDO06478.1 - 0.002 18.9 0.0 0.0037 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDO06478.1 - 0.039 13.3 0.0 0.076 12.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 EDO06478.1 - 0.043 14.3 0.0 0.089 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EDO06478.1 - 0.065 12.2 0.0 0.15 11.0 0.0 1.6 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 EDO06478.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EDO06478.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Myb_DNA-bind_6 PF13921.1 EDO06479.1 - 3.5e-17 62.2 3.1 1.8e-08 34.3 0.3 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDO06479.1 - 4.5e-16 58.6 1.6 2.5e-08 33.8 0.5 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDO06479.1 - 0.02 15.0 4.4 0.25 11.5 1.3 3.4 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 EDO06479.1 - 0.051 13.4 1.2 0.13 12.1 0.1 2.2 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Pkinase PF00069.20 EDO06480.1 - 9.9e-25 87.1 0.0 1.9e-23 82.9 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO06480.1 - 2.2e-12 46.5 0.0 9.7e-12 44.5 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EDO06480.1 - 0.0034 17.1 0.1 0.038 13.7 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EDO06480.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EDO06480.1 - 0.028 13.4 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arf PF00025.16 EDO06481.1 - 8.7e-12 44.6 0.1 6.6e-11 41.7 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDO06481.1 - 0.00037 19.7 0.2 0.0099 15.1 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EDO06481.1 - 0.0026 18.2 0.1 0.0045 17.4 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDO06481.1 - 0.014 15.3 0.5 0.063 13.2 0.3 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EDO06481.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EDO06481.1 - 0.12 12.3 0.1 0.2 11.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 EDO06481.1 - 0.12 11.4 2.9 0.82 8.7 2.0 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 EDO06481.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EDO06481.1 - 0.13 11.9 0.5 8.8 5.9 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DUF2945 PF11160.3 EDO06481.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2945) SSB PF00436.20 EDO06483.1 - 6.8e-11 41.9 0.2 1e-10 41.4 0.2 1.2 1 0 0 1 1 1 1 Single-strand binding protein family DNA_primase_S PF01896.14 EDO06484.1 - 5.8e-44 149.4 0.3 8.2e-44 148.9 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DYW_deaminase PF14432.1 EDO06484.1 - 0.14 12.1 0.5 0.4 10.6 0.3 1.7 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases CTP_synth_N PF06418.9 EDO06485.1 - 1.9e-107 358.4 0.0 4e-107 357.4 0.0 1.5 1 1 1 2 2 2 1 CTP synthase N-terminus GATase PF00117.23 EDO06485.1 - 1.9e-41 141.6 0.0 3.2e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EDO06485.1 - 7.5e-07 28.8 0.0 2e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EDO06485.1 - 0.0035 16.7 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PA28_beta PF02252.13 EDO06486.1 - 2.1e-60 202.5 3.1 3.8e-60 201.7 2.2 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 EDO06486.1 - 0.059 13.5 0.2 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit Med28 PF11594.3 EDO06486.1 - 0.1 12.8 0.7 0.35 11.1 0.1 2.1 1 1 0 2 2 2 0 Mediator complex subunit 28 TBPIP PF07106.8 EDO06486.1 - 0.18 11.3 3.7 0.48 9.9 0.0 2.6 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SUI1 PF01253.17 EDO06487.1 - 1.1e-09 38.0 0.0 2.2e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.15 EDO06487.1 - 0.0016 18.1 0.0 0.0043 16.7 0.0 1.8 1 0 0 1 1 1 1 PUA domain SCIMP PF15050.1 EDO06487.1 - 0.028 14.3 0.2 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 SCIMP protein DUF544 PF04424.8 EDO06489.1 - 8.4e-07 28.8 0.2 1.9e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF2012 PF09430.5 EDO06489.1 - 0.036 13.9 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Sec63 PF02889.11 EDO06490.1 - 4.5e-40 137.7 0.0 6e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EDO06490.1 - 3.1e-20 71.6 0.1 7.4e-20 70.4 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain PLAC8 PF04749.12 EDO06490.1 - 0.061 13.8 1.3 0.2 12.2 0.2 2.4 3 0 0 3 3 3 0 PLAC8 family AAA_13 PF13166.1 EDO06491.1 - 1.7e-05 23.5 30.3 3e-05 22.7 12.7 2.0 1 1 1 2 2 2 2 AAA domain IFT57 PF10498.4 EDO06491.1 - 0.00032 19.5 13.4 0.00032 19.5 9.3 3.0 1 1 2 3 3 3 1 Intra-flagellar transport protein 57 SlyX PF04102.7 EDO06491.1 - 0.0025 18.1 21.0 0.0063 16.8 0.1 5.0 3 1 2 5 5 5 1 SlyX DUF3552 PF12072.3 EDO06491.1 - 0.0046 16.1 9.2 0.0046 16.1 6.4 2.9 1 1 2 3 3 3 1 Domain of unknown function (DUF3552) Prefoldin PF02996.12 EDO06491.1 - 0.0047 16.5 1.1 0.0047 16.5 0.8 4.4 2 1 0 3 3 3 1 Prefoldin subunit Myosin_tail_1 PF01576.14 EDO06491.1 - 0.0093 13.7 35.8 0.081 10.6 7.7 2.1 1 1 1 2 2 2 2 Myosin tail ATG16 PF08614.6 EDO06491.1 - 0.035 13.9 33.6 0.26 11.0 7.9 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.6 EDO06491.1 - 0.043 12.1 25.6 0.053 11.8 7.1 2.7 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fib_alpha PF08702.5 EDO06491.1 - 0.07 13.2 28.5 0.15 12.1 8.4 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 EDO06491.1 - 0.09 11.9 10.5 0.7 9.0 2.8 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein PAH PF02671.16 EDO06491.1 - 0.1 12.2 1.3 0.2 11.2 0.2 2.1 2 0 0 2 2 2 0 Paired amphipathic helix repeat Spc7 PF08317.6 EDO06491.1 - 0.11 11.0 33.9 0.24 10.0 8.6 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF3450 PF11932.3 EDO06491.1 - 0.14 11.3 22.9 0.38 9.9 1.6 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF812 PF05667.6 EDO06491.1 - 0.16 10.4 29.7 0.04 12.4 15.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF4349 PF14257.1 EDO06491.1 - 0.17 11.0 9.6 0.38 9.9 5.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) HTH_Tnp_Tc3_1 PF11427.3 EDO06491.1 - 0.19 11.4 0.9 0.76 9.4 0.2 2.4 1 1 1 2 2 2 0 Tc3 transposase WEMBL PF05701.6 EDO06491.1 - 0.29 9.5 29.9 0.16 10.3 18.7 1.7 1 1 1 2 2 2 0 Weak chloroplast movement under blue light MCPsignal PF00015.16 EDO06491.1 - 0.31 10.5 14.4 0.38 10.2 0.7 2.8 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Atg14 PF10186.4 EDO06491.1 - 0.33 9.8 31.5 0.16 10.8 12.2 2.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 EDO06491.1 - 0.56 10.0 18.1 3 7.6 4.8 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.1 EDO06491.1 - 0.57 10.1 20.6 1.1 9.1 0.2 4.1 2 1 1 4 4 4 0 FlxA-like protein DUF948 PF06103.6 EDO06491.1 - 0.62 9.9 16.8 1.2 9.0 1.0 4.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) MerR-DNA-bind PF09278.6 EDO06491.1 - 1 9.7 8.1 29 5.1 1.9 3.8 2 1 1 3 3 3 0 MerR, DNA binding Sugarporin_N PF11471.3 EDO06491.1 - 1.3 8.7 9.5 0.29 10.8 0.3 3.0 2 1 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Med9 PF07544.8 EDO06491.1 - 2.7 7.8 17.6 1.1 9.0 1.7 3.5 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 BRCA2 PF00634.13 EDO06491.1 - 3.3 7.0 4.9 14 5.0 0.2 3.0 3 0 0 3 3 3 0 BRCA2 repeat Hema_stalk PF08720.5 EDO06491.1 - 3.5 7.1 8.6 10 5.5 1.0 2.4 1 1 0 2 2 2 0 Influenza C hemagglutinin stalk Tropomyosin_1 PF12718.2 EDO06491.1 - 4.6 7.0 31.8 13 5.5 0.1 3.5 2 1 2 4 4 4 0 Tropomyosin like Laminin_II PF06009.7 EDO06491.1 - 6.1 6.6 27.1 1.6 8.4 6.6 3.4 1 1 3 4 4 4 0 Laminin Domain II Cortex-I_coil PF09304.5 EDO06491.1 - 7.1 6.7 30.3 0.51 10.4 5.5 3.8 1 1 3 4 4 4 0 Cortexillin I, coiled coil IncA PF04156.9 EDO06491.1 - 8 6.0 33.6 3.2 7.3 12.1 3.2 1 1 2 3 3 3 0 IncA protein Solute_trans_a PF03619.11 EDO06493.1 - 1.4e-50 172.2 13.1 2e-50 171.6 9.1 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha cNMP_binding PF00027.24 EDO06494.1 - 1.6e-36 124.0 0.1 3.9e-21 74.6 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Corona_RPol_N PF06478.8 EDO06494.1 - 0.041 12.5 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 Coronavirus RPol N-terminus Peptidase_U35_2 PF14550.1 EDO06496.1 - 0.019 14.5 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative phage protease XkdF Rhamno_transf PF11316.3 EDO06498.1 - 0.0036 16.5 2.1 0.0045 16.2 1.5 1.1 1 0 0 1 1 1 1 Putative rhamnosyl transferase ERM PF00769.14 EDO06498.1 - 0.018 14.5 25.3 0.024 14.1 17.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Borrelia_P83 PF05262.6 EDO06498.1 - 0.032 12.5 15.4 0.033 12.4 10.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Birna_RdRp PF04197.7 EDO06498.1 - 0.086 10.8 10.0 0.099 10.6 6.9 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) 7TM_transglut PF14402.1 EDO06498.1 - 0.41 9.5 1.6 0.52 9.1 1.1 1.1 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Asp-B-Hydro_N PF05279.6 EDO06498.1 - 0.49 10.2 18.3 0.6 9.9 12.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Neur_chan_memb PF02932.11 EDO06498.1 - 0.5 10.2 9.6 0.71 9.7 6.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOBP PF15279.1 EDO06498.1 - 0.87 9.9 10.0 0.94 9.7 7.0 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Ycf1 PF05758.7 EDO06498.1 - 2.1 5.9 11.9 2.2 5.9 8.3 1.1 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 EDO06498.1 - 8.1 5.7 18.6 12 5.1 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AP2 PF00847.15 EDO06499.1 - 1.8e-05 24.7 0.8 3.3e-05 23.9 0.5 1.5 1 0 0 1 1 1 1 AP2 domain Acyl-CoA_dh_2 PF08028.6 EDO06499.1 - 0.0033 17.6 0.3 5.3 7.2 0.3 3.0 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain DEAD PF00270.24 EDO06500.1 - 7.8e-38 129.6 0.0 2.6e-37 127.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO06500.1 - 8.9e-18 63.9 0.0 2.1e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EDO06500.1 - 2.5e-05 23.7 0.2 0.0001 21.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EDO06500.1 - 0.00079 19.3 0.0 0.0086 15.9 0.0 2.6 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDO06500.1 - 0.03 14.4 0.0 0.13 12.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain CAF1A PF12253.3 EDO06501.1 - 1.9e-06 27.8 7.6 6.2e-06 26.2 5.3 1.9 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A PX PF00787.19 EDO06501.1 - 0.0087 15.8 1.0 32 4.3 0.0 4.0 5 0 0 5 5 5 2 PX domain DEAD PF00270.24 EDO06502.1 - 1e-20 73.9 0.0 2.8e-20 72.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO06502.1 - 1.3e-17 63.3 0.0 8.4e-16 57.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO06502.1 - 0.002 17.9 0.0 0.013 15.3 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit TH1 PF04858.8 EDO06502.1 - 0.11 10.6 0.3 0.18 9.9 0.2 1.2 1 0 0 1 1 1 0 TH1 protein DKCLD PF08068.7 EDO06503.1 - 3.9e-29 100.3 0.8 5.1e-28 96.7 0.0 3.1 4 0 0 4 4 4 1 DKCLD (NUC011) domain TruB_N PF01509.13 EDO06503.1 - 1.1e-24 87.3 0.7 1.8e-16 60.6 0.1 3.2 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EDO06503.1 - 8.6e-16 57.4 1.6 8.6e-16 57.4 1.1 1.6 2 0 0 2 2 2 1 PUA domain Not1 PF04054.10 EDO06504.1 - 1.8e-48 165.3 8.0 1.8e-48 165.3 5.5 2.5 3 1 0 3 3 3 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EDO06504.1 - 4.1e-17 62.2 1.2 4.1e-17 62.2 0.8 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) Peptidase_C54 PF03416.14 EDO06505.1 - 2.1e-25 89.4 0.0 1.2e-15 57.3 0.0 2.1 1 1 1 2 2 2 2 Peptidase family C54 Peptidase_C78 PF07910.8 EDO06505.1 - 0.039 13.0 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C78 HSA PF07529.8 EDO06506.1 - 0.0061 16.3 0.2 0.017 14.8 0.1 1.8 1 0 0 1 1 1 1 HSA cNMP_binding PF00027.24 EDO06507.1 - 1.2e-34 117.9 0.1 4.4e-12 45.6 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain DUF904 PF06005.7 EDO06507.1 - 0.19 12.0 2.6 0.25 11.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF904) PHO4 PF01384.15 EDO06508.1 - 1.5e-103 345.9 20.2 2.1e-103 345.4 14.0 1.2 1 0 0 1 1 1 1 Phosphate transporter family Host_attach PF10116.4 EDO06509.1 - 1.3 9.2 8.0 2.4 8.3 5.6 1.4 1 0 0 1 1 1 0 Protein required for attachment to host cells Dpy19 PF10034.4 EDO06510.1 - 2.9e-48 164.5 7.2 2e-25 89.0 9.8 2.7 1 1 1 2 2 2 2 Q-cell neuroblast polarisation SKIP_SNW PF02731.10 EDO06511.1 - 3e-61 205.4 6.5 3e-61 205.4 4.5 2.7 3 0 0 3 3 3 1 SKIP/SNW domain AvrPphF-ORF-2 PF09143.5 EDO06511.1 - 0.57 9.8 3.3 2.9 7.5 0.0 2.6 3 0 0 3 3 3 0 AvrPphF-ORF-2 GBP PF02263.14 EDO06512.1 - 5.4e-13 48.5 4.2 2.7e-09 36.4 0.0 3.0 3 0 0 3 3 3 2 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EDO06512.1 - 0.018 14.9 0.7 0.08 12.7 0.1 2.5 2 1 0 2 2 2 0 Dynamin family cwf21 PF08312.7 EDO06513.1 - 0.05 13.4 7.0 0.1 12.4 4.8 1.5 1 0 0 1 1 1 0 cwf21 domain DnaJ-X PF14308.1 EDO06514.1 - 9.6e-29 100.1 0.4 4.2e-28 98.0 0.3 1.9 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 EDO06514.1 - 2e-24 85.0 2.8 4.6e-24 83.9 1.9 1.6 1 0 0 1 1 1 1 DnaJ domain Glyco_tran_28_C PF04101.11 EDO06515.1 - 8.7e-20 71.0 0.2 1.1e-19 70.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain LUC7 PF03194.10 EDO06516.1 - 1.5e-54 185.1 8.7 3e-54 184.2 6.1 1.4 1 1 0 1 1 1 1 LUC7 N_terminus DUF1509 PF07420.6 EDO06516.1 - 2.5 7.2 14.6 4.1 6.5 10.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) rRNA_proc-arch PF13234.1 EDO06517.1 - 4.1e-57 193.3 4.4 4.1e-57 193.3 3.0 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 EDO06517.1 - 2.1e-55 186.7 0.5 5.5e-55 185.3 0.2 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EDO06517.1 - 4.7e-21 75.0 0.0 2e-20 72.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO06517.1 - 2.5e-08 33.6 0.1 1e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FANCI_S2 PF14676.1 EDO06517.1 - 0.019 14.8 1.0 2 8.2 0.2 2.7 2 0 0 2 2 2 0 FANCI solenoid 2 Ribosomal_L29 PF00831.18 EDO06517.1 - 1.7 8.4 9.6 0.28 10.9 3.3 2.3 2 0 0 2 2 2 0 Ribosomal L29 protein MAT1 PF06391.8 EDO06519.1 - 1.1e-08 34.9 1.9 1.7e-08 34.2 1.3 1.3 1 1 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 C2 PF00168.25 EDO06520.1 - 1e-29 102.1 0.0 1.4e-06 28.0 0.0 5.6 5 0 0 5 5 5 5 C2 domain FerI PF08151.7 EDO06520.1 - 0.011 15.7 0.0 0.034 14.1 0.0 1.9 1 0 0 1 1 1 0 FerI (NUC094) domain E1-E2_ATPase PF00122.15 EDO06521.1 - 3.7e-69 232.2 4.8 1.8e-68 230.0 1.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDO06521.1 - 3.4e-44 150.5 3.8 3.4e-44 150.5 2.6 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDO06521.1 - 5.4e-34 118.4 0.0 4.2e-33 115.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDO06521.1 - 1e-19 69.7 0.9 2.2e-19 68.7 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EDO06521.1 - 1.7e-16 59.8 0.0 3.8e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDO06521.1 - 2e-15 57.4 0.0 4.5e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDO06521.1 - 1.1e-05 25.1 2.3 0.00012 21.7 1.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TRM PF02005.11 EDO06522.1 - 4.9e-92 308.7 0.2 7e-72 242.4 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 EDO06522.1 - 4.7e-05 23.3 0.0 0.00013 21.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ras PF00071.17 EDO06523.1 - 8.3e-15 54.5 0.0 6.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EDO06523.1 - 6.5e-06 26.6 0.0 0.023 15.2 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EDO06523.1 - 0.0016 17.6 0.0 0.7 8.9 0.0 2.1 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region NACHT PF05729.7 EDO06523.1 - 0.019 14.6 0.0 0.54 9.9 0.0 2.6 2 1 1 3 3 3 0 NACHT domain MobB PF03205.9 EDO06523.1 - 0.022 14.4 0.0 0.058 13.0 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EDO06523.1 - 0.053 13.4 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 EDO06523.1 - 0.062 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EDO06523.1 - 0.092 12.2 0.0 1.5 8.3 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EDO06523.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain TAFII55_N PF04658.8 EDO06524.1 - 2.4e-35 121.4 0.1 4.8e-35 120.4 0.1 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region A_deaminase PF00962.17 EDO06524.1 - 0.0048 15.8 0.0 0.005 15.8 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF1128 PF06569.6 EDO06524.1 - 1.5 8.5 4.2 0.69 9.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) tRNA-synt_1 PF00133.17 EDO06527.1 - 1e-98 330.9 0.0 1.5e-98 330.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EDO06527.1 - 9.5e-15 54.6 0.1 2.4e-14 53.3 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EDO06527.1 - 1.8e-14 53.2 3.4 5.1e-06 25.3 0.0 4.1 5 0 0 5 5 5 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 EDO06527.1 - 2.5e-05 23.7 3.9 2.5e-05 23.7 2.7 2.1 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS MPC PF03650.8 EDO06528.1 - 2.8e-34 117.6 0.2 3.5e-34 117.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) U1snRNP70_N PF12220.3 EDO06530.1 - 2.8e-24 85.2 2.1 4.5e-24 84.5 1.4 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EDO06530.1 - 2.1e-18 65.7 0.0 3.6e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06530.1 - 6.2e-14 51.7 0.0 9.6e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06530.1 - 5.8e-08 32.4 0.0 9.8e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_1 PF00175.16 EDO06531.1 - 1.1e-10 41.9 0.0 2.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EDO06531.1 - 2.2e-06 27.7 0.0 0.00031 20.7 0.0 2.7 2 1 1 3 3 3 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EDO06531.1 - 0.016 15.1 0.3 0.56 10.1 0.0 2.4 1 1 0 2 2 2 0 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EDO06531.1 - 0.036 14.0 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Kp4 PF09044.5 EDO06532.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Kp4 Flavodoxin_2 PF02525.12 EDO06532.1 - 4.2 6.8 10.5 2.1 7.8 1.7 2.1 1 1 1 2 2 2 0 Flavodoxin-like fold RRM_1 PF00076.17 EDO06533.1 - 8.4e-17 60.5 0.0 1.3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06533.1 - 5.7e-12 45.4 0.0 9.5e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06533.1 - 3.4e-09 36.3 0.0 6.1e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1188 PF06690.6 EDO06533.1 - 0.03 13.4 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Sel1 PF08238.7 EDO06534.1 - 3.6e-11 43.3 19.9 0.0015 19.0 0.3 6.9 6 1 1 7 7 7 4 Sel1 repeat 5_3_exonuc_N PF02739.11 EDO06535.1 - 4.1e-26 91.3 0.2 3e-19 69.0 0.0 2.8 3 0 0 3 3 3 2 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.15 EDO06535.1 - 1e-19 70.5 0.0 1.8e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF3332 PF11810.3 EDO06535.1 - 0.0018 17.9 0.0 0.0039 16.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3332) U3_assoc_6 PF08640.6 EDO06535.1 - 0.056 13.2 0.1 2.8 7.7 0.1 2.5 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Peptidase_S29 PF02907.10 EDO06537.1 - 0.12 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease ATP-synt_D PF01813.12 EDO06539.1 - 0.0078 15.7 1.0 0.011 15.3 0.7 1.3 1 0 0 1 1 1 1 ATP synthase subunit D DUF4303 PF14136.1 EDO06539.1 - 0.01 15.4 0.3 0.01 15.4 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) CIAPIN1 PF05093.8 EDO06539.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.6 1 1 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis MCM PF00493.18 EDO06540.1 - 2.2e-119 398.1 0.0 1.2e-117 392.4 0.0 2.2 1 1 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EDO06540.1 - 2.7e-17 63.1 20.5 2.7e-17 63.1 14.2 2.8 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EDO06540.1 - 1.8e-12 47.8 0.5 5.7e-12 46.1 0.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDO06540.1 - 1.1e-08 34.5 0.1 3.8e-06 26.2 0.0 2.9 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDO06540.1 - 1.8e-05 24.5 0.0 5.3e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EDO06540.1 - 0.00016 21.1 0.0 0.0009 18.7 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EDO06540.1 - 0.013 15.1 0.0 0.04 13.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EDO06540.1 - 0.034 14.3 0.0 0.18 12.0 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CHCH PF06747.8 EDO06541.1 - 1.3e-08 34.4 1.9 2.7e-05 23.9 0.4 2.7 2 1 0 2 2 2 2 CHCH domain DUF1903 PF08991.5 EDO06541.1 - 0.66 10.1 5.2 0.38 10.9 1.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1903) Cmc1 PF08583.5 EDO06541.1 - 0.76 9.6 6.8 1.7 8.4 0.8 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 EDO06541.1 - 1.8 8.6 5.3 19 5.3 4.2 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb UFD1 PF03152.9 EDO06542.1 - 8.9e-74 246.4 0.0 1.1e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EDO06542.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Rhomboid PF01694.17 EDO06543.1 - 2.7e-24 85.8 9.7 2.7e-24 85.8 6.7 2.0 2 0 0 2 2 2 1 Rhomboid family Rhomboid PF01694.17 EDO06544.1 - 4.8e-25 88.2 11.1 4.8e-25 88.2 7.7 1.7 2 0 0 2 2 2 1 Rhomboid family DUF3938 PF13074.1 EDO06544.1 - 0.21 11.4 1.4 0.77 9.6 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3938) Rhomboid PF01694.17 EDO06545.1 - 4.6e-25 88.3 11.1 4.6e-25 88.3 7.7 1.9 3 0 0 3 3 3 1 Rhomboid family DUF3938 PF13074.1 EDO06545.1 - 0.21 11.4 1.4 0.77 9.6 1.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3938) Proteasome PF00227.21 EDO06547.1 - 9.2e-38 129.4 0.2 8.2e-21 74.1 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Ras PF00071.17 EDO06548.1 - 8.1e-51 171.6 0.0 9.8e-51 171.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO06548.1 - 1.9e-17 63.8 0.0 2.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO06548.1 - 5.5e-14 51.7 0.0 7.1e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDO06548.1 - 2.2e-07 30.4 0.1 6.4e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO06548.1 - 7.7e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EDO06548.1 - 0.00013 21.1 0.0 0.00016 20.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DAP3 PF10236.4 EDO06548.1 - 0.079 11.8 0.0 0.31 9.9 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.1 EDO06548.1 - 0.14 12.2 0.1 1.9 8.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain Nol1_Nop2_Fmu PF01189.12 EDO06549.1 - 3.5e-84 282.5 0.0 4.4e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EDO06549.1 - 0.0001 22.3 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EDO06549.1 - 0.0011 18.6 0.1 0.0017 17.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO06549.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.12 EDO06549.1 - 0.0043 16.0 0.0 0.0082 15.0 0.0 1.4 1 0 0 1 1 1 1 Fibrillarin PCMT PF01135.14 EDO06549.1 - 0.019 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 EDO06549.1 - 0.028 13.9 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Profilin PF00235.14 EDO06550.1 - 1.3e-07 31.7 0.1 1.6e-07 31.4 0.1 1.3 1 1 0 1 1 1 1 Profilin DUF2590 PF10761.4 EDO06550.1 - 0.092 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2590) DUF3208 PF11482.3 EDO06550.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3208) DUF21 PF01595.15 EDO06551.1 - 5.9e-31 107.1 5.1 7.7e-31 106.7 3.5 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EDO06551.1 - 0.00088 19.0 2.9 0.58 9.9 0.2 2.7 2 0 0 2 2 2 2 CBS domain DUF1212 PF06738.7 EDO06551.1 - 3 7.2 6.6 0.72 9.2 0.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1212) Sulfate_transp PF00916.15 EDO06553.1 - 5.3e-23 81.4 13.9 5.3e-23 81.4 9.6 3.4 4 0 0 4 4 4 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EDO06553.1 - 1.3e-13 50.3 1.6 1.3e-13 50.3 1.1 2.7 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif Herpes_U55 PF06501.6 EDO06553.1 - 0.00011 20.9 0.0 0.00018 20.2 0.0 1.2 1 0 0 1 1 1 1 Human herpesvirus U55 protein STAS PF01740.16 EDO06553.1 - 0.0033 16.8 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain Nop PF01798.13 EDO06554.1 - 7.8e-54 181.0 0.5 1.4e-53 180.2 0.3 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EDO06554.1 - 5.6e-24 83.7 0.0 2.6e-23 81.5 0.0 2.0 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EDO06554.1 - 1.2e-20 73.3 0.2 2.6e-20 72.3 0.1 1.6 1 0 0 1 1 1 1 NOP5NT (NUC127) domain SIP1 PF04938.7 EDO06555.1 - 1.5e-06 27.7 0.0 3e-06 26.7 0.0 1.4 2 0 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Rep-A_N PF04057.7 EDO06555.1 - 0.045 13.5 0.1 7.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Replication factor-A protein 1, N-terminal domain Borealin PF10512.4 EDO06555.1 - 0.095 12.6 0.0 2.7 7.9 0.0 2.4 1 1 1 2 2 2 0 Cell division cycle-associated protein 8 Metallophos PF00149.23 EDO06556.1 - 4.9e-12 45.6 2.5 8e-12 44.9 1.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DBR1 PF05011.8 EDO06556.1 - 1.1e-10 41.5 0.0 2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos_2 PF12850.2 EDO06556.1 - 0.00076 19.3 0.4 0.0016 18.2 0.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Rhomboid PF01694.17 EDO06557.1 - 5.5e-16 58.9 15.1 5.5e-16 58.9 10.5 2.1 2 1 0 2 2 2 1 Rhomboid family DUF3270 PF11674.3 EDO06557.1 - 1 9.4 4.0 2.7 8.0 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) NPL4 PF05021.10 EDO06559.1 - 9.9e-75 251.5 0.0 1.3e-74 251.1 0.0 1.1 1 0 0 1 1 1 1 NPL4 family UN_NPL4 PF11543.3 EDO06559.1 - 9.2e-11 41.8 0.1 2.1e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 zf-NPL4 PF05020.10 EDO06559.1 - 2.6e-05 23.9 0.0 5.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region Rad60-SLD PF11976.3 EDO06559.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rhomboid PF01694.17 EDO06560.1 - 4.7e-18 65.6 7.9 4.7e-18 65.6 5.5 1.5 2 0 0 2 2 2 1 Rhomboid family DUF161 PF02588.10 EDO06560.1 - 3.3 8.0 7.3 37 4.7 5.4 2.6 1 1 1 2 2 2 0 Uncharacterized BCR, YitT family COG1284 Ribosomal_L4 PF00573.17 EDO06561.1 - 7.3e-44 149.4 0.9 7.3e-44 149.4 0.7 1.6 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EDO06561.1 - 3.1e-05 23.7 0.2 0.00011 22.0 0.2 2.0 1 1 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain MORN PF02493.15 EDO06562.1 - 0.00017 21.0 16.9 0.003 17.1 1.4 4.1 4 0 0 4 4 4 2 MORN repeat Guanylate_kin PF00625.16 EDO06566.1 - 1.5e-43 148.4 0.0 1.7e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 EDO06566.1 - 2.5e-06 27.8 0.1 3.7e-05 24.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDO06566.1 - 3.3e-06 27.0 0.0 0.00034 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDO06566.1 - 1.5e-05 25.7 0.0 0.00011 22.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 EDO06566.1 - 3.7e-05 23.8 0.0 7.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EDO06566.1 - 0.00028 21.0 0.0 0.00085 19.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EDO06566.1 - 0.00047 20.4 0.0 0.0007 19.9 0.0 1.4 1 1 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EDO06566.1 - 0.00065 18.9 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 EDO06566.1 - 0.0011 18.7 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EDO06566.1 - 0.002 18.1 0.0 0.0049 16.8 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EDO06566.1 - 0.0034 16.8 0.2 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain AAA_14 PF13173.1 EDO06566.1 - 0.0043 16.9 0.0 0.0071 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EDO06566.1 - 0.0045 16.7 0.3 0.0078 15.9 0.2 1.7 1 1 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 EDO06566.1 - 0.0077 16.3 0.0 0.012 15.8 0.0 1.4 1 1 0 1 1 1 1 RNA helicase NB-ARC PF00931.17 EDO06566.1 - 0.013 14.3 0.0 0.027 13.3 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 EDO06566.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EDO06566.1 - 0.021 14.7 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EDO06566.1 - 0.025 14.2 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 EDO06566.1 - 0.032 14.1 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EDO06566.1 - 0.037 13.7 0.2 0.1 12.3 0.0 1.8 2 1 0 2 2 2 0 NTPase AAA_5 PF07728.9 EDO06566.1 - 0.057 13.1 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.7 EDO06566.1 - 0.067 12.4 0.1 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein MMR_HSR1 PF01926.18 EDO06566.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 EDO06566.1 - 0.073 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 EDO06566.1 - 0.077 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_15 PF13175.1 EDO06566.1 - 0.097 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EDO06566.1 - 0.1 12.1 0.0 0.31 10.6 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EDO06566.1 - 0.17 12.1 1.0 0.41 10.9 0.7 1.9 1 1 0 1 1 1 0 AAA domain PFK PF00365.15 EDO06567.1 - 2.9e-36 124.8 0.0 1.1e-22 80.3 0.0 2.3 2 0 0 2 2 2 2 Phosphofructokinase zf-C3HC PF07967.8 EDO06568.1 - 0.0041 16.8 0.0 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 C3HC zinc finger-like IPPT PF01715.12 EDO06568.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 IPP transferase RXT2_N PF08595.6 EDO06568.1 - 0.23 11.2 0.3 0.54 10.0 0.2 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Pro_isomerase PF00160.16 EDO06569.1 - 2.3e-49 167.5 0.2 4.1e-49 166.7 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EDO06569.1 - 2e-08 33.8 0.7 6.2e-05 22.3 0.0 3.2 2 1 1 3 3 3 2 Rtf2 RING-finger zf-Nse PF11789.3 EDO06569.1 - 1.6e-07 30.6 0.2 2.6e-06 26.8 0.1 2.7 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EDO06569.1 - 3.2e-06 26.9 0.1 3.3e-05 23.7 0.0 2.7 3 0 0 3 3 3 1 U-box domain KOW PF00467.24 EDO06570.1 - 0.011 15.3 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 KOW motif YpzI PF14140.1 EDO06571.1 - 0.00073 18.9 8.0 26 4.4 0.1 6.3 1 1 5 6 6 6 3 YpzI-like protein DUF1425 PF07233.7 EDO06571.1 - 5.3 6.6 12.4 30 4.2 0.2 5.2 2 1 4 6 6 6 0 Protein of unknown function (DUF1425) CK_II_beta PF01214.13 EDO06573.1 - 3.9e-66 222.0 0.0 6.5e-66 221.3 0.0 1.3 2 0 0 2 2 2 1 Casein kinase II regulatory subunit Ribosomal_L33 PF00471.15 EDO06573.1 - 0.1 12.8 0.7 0.2 11.9 0.5 1.4 1 0 0 1 1 1 0 Ribosomal protein L33 PseudoU_synth_2 PF00849.17 EDO06575.1 - 0.00074 19.3 0.0 0.0017 18.2 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase DIL PF01843.14 EDO06575.1 - 0.04 13.7 2.7 0.25 11.2 1.9 2.2 1 1 0 1 1 1 0 DIL domain Hom_end PF05204.9 EDO06575.1 - 1.2 9.1 5.7 1.4 8.9 0.6 2.7 2 1 1 3 3 3 0 Homing endonuclease RNase_H2_suC PF08615.6 EDO06576.1 - 2.6e-16 59.6 0.0 3.4e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Peptidase_M8 PF01457.11 EDO06576.1 - 0.1 10.9 0.1 0.13 10.5 0.1 1.1 1 0 0 1 1 1 0 Leishmanolysin UBN2_2 PF14227.1 EDO06577.1 - 0.0071 15.9 1.8 0.024 14.1 0.9 2.2 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type PIP49_C PF12260.3 EDO06577.1 - 0.01 15.2 2.8 0.012 15.0 0.5 2.2 2 1 0 2 2 2 0 Protein-kinase domain of FAM69 TLD PF07534.11 EDO06578.1 - 7.3e-32 110.2 1.5 1.1e-31 109.6 1.0 1.3 1 0 0 1 1 1 1 TLD GRAM PF02893.15 EDO06578.1 - 0.049 13.1 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 GRAM domain SRP-alpha_N PF04086.8 EDO06579.1 - 3.1 7.1 17.9 5.7 6.2 12.4 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PPP4R2 PF09184.6 EDO06580.1 - 4.4e-07 29.7 0.0 5.8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 PPP4R2 TEP1_N PF05386.6 EDO06581.1 - 0.026 13.9 3.4 0.26 10.7 0.2 2.7 2 0 0 2 2 2 0 TEP1 N-terminal domain RAP PF08373.5 EDO06581.1 - 0.067 12.9 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 RAP domain Prp31_C PF09785.4 EDO06582.1 - 5.6e-41 139.8 1.8 4.7e-40 136.8 1.3 2.2 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 EDO06582.1 - 4.1e-31 107.3 3.4 5e-30 103.7 0.7 2.8 2 1 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 EDO06582.1 - 2.7e-15 55.9 0.9 5e-15 55.0 0.6 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain MogR_DNAbind PF12181.3 EDO06582.1 - 0.018 14.7 0.1 0.045 13.5 0.1 1.6 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) DUF3402 PF11882.3 EDO06582.1 - 0.35 9.8 3.0 0.31 10.0 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3402) ubiquitin PF00240.18 EDO06583.1 - 3.2e-07 29.6 0.0 6e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin family Pro_isomerase PF00160.16 EDO06584.1 - 2.8e-39 134.8 0.0 4e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LRR_4 PF12799.2 EDO06585.1 - 3e-11 42.6 25.6 0.00045 19.7 0.9 7.3 5 2 0 6 6 6 4 Leucine Rich repeats (2 copies) CAP_GLY PF01302.20 EDO06585.1 - 6.9e-10 38.4 0.0 1.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.1 EDO06585.1 - 1e-07 31.6 26.0 0.0018 17.9 3.5 5.3 3 2 3 6 6 6 5 Leucine rich repeat LRR_6 PF13516.1 EDO06585.1 - 0.0066 16.4 21.3 4.4 7.6 0.3 8.6 9 0 0 9 9 9 1 Leucine Rich repeat LRR_9 PF14580.1 EDO06585.1 - 0.074 12.6 2.2 0.17 11.4 0.3 2.4 1 1 2 3 3 3 0 Leucine-rich repeat LRR_7 PF13504.1 EDO06585.1 - 2.9 8.4 24.6 7.6 7.2 0.4 7.8 9 0 0 9 9 9 0 Leucine rich repeat LRR_1 PF00560.28 EDO06585.1 - 8.8 6.7 27.7 7.5 7.0 0.1 7.9 6 2 1 7 7 7 0 Leucine Rich Repeat PCNA_N PF00705.13 EDO06586.1 - 1e-27 96.1 0.4 2.6e-27 94.8 0.2 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EDO06586.1 - 1.4e-22 79.9 0.2 2.3e-21 76.0 0.0 2.2 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EDO06586.1 - 1.5e-08 34.0 0.0 9.2e-08 31.5 0.0 2.0 1 1 0 1 1 1 1 Rad9 Rad1 PF02144.11 EDO06586.1 - 0.0002 20.2 0.1 0.071 11.8 0.0 2.2 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Thioredoxin PF00085.15 EDO06588.1 - 1.6e-26 91.9 0.0 2.8e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EDO06588.1 - 3.3e-06 27.1 0.1 0.0044 17.1 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EDO06588.1 - 1.3e-05 25.3 0.0 0.00011 22.3 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EDO06588.1 - 0.00094 18.7 0.1 0.0015 18.1 0.1 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_6 PF13848.1 EDO06588.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EDO06588.1 - 0.0033 17.0 0.1 0.01 15.4 0.0 2.1 1 1 1 2 2 2 1 AhpC/TSA family TraF PF13728.1 EDO06588.1 - 0.0096 15.4 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 EDO06588.1 - 0.01 15.8 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.1 EDO06588.1 - 0.027 14.2 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain BTD PF09270.5 EDO06588.1 - 0.071 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain MMR_HSR1 PF01926.18 EDO06589.1 - 1.3e-09 37.9 0.1 5.7e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.16 EDO06589.1 - 0.015 14.5 0.0 3.9 6.6 0.0 2.2 1 1 1 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.18 EDO06589.1 - 0.019 14.7 0.3 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 Dynamin family MobB PF03205.9 EDO06589.1 - 0.031 13.9 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EDO06589.1 - 0.057 12.3 0.0 0.13 11.1 0.0 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein Gtr1_RagA PF04670.7 EDO06589.1 - 0.1 11.7 0.0 0.24 10.5 0.0 1.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region IIGP PF05049.8 EDO06589.1 - 0.19 10.5 0.0 0.43 9.3 0.0 1.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Fer4_2 PF12797.2 EDO06589.1 - 2.9 7.9 4.6 0.84 9.6 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain PRCC PF10253.4 EDO06590.1 - 5.2e-19 69.6 4.5 5.2e-19 69.6 3.2 1.6 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Mito_carr PF00153.22 EDO06592.1 - 1e-55 185.4 0.5 2.3e-19 68.8 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Polysacc_synt_C PF14667.1 EDO06592.1 - 0.051 13.3 0.4 2.2 8.0 0.0 2.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain 14-3-3 PF00244.15 EDO06593.1 - 1.7e-104 348.0 9.9 1.9e-104 347.9 6.9 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4518 PF15008.1 EDO06593.1 - 0.038 13.0 0.3 0.069 12.1 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) DUF3106 PF11304.3 EDO06593.1 - 0.21 12.0 2.3 1.5 9.2 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3106) Fcf1 PF04900.7 EDO06594.1 - 1.6e-38 130.8 1.6 2.6e-38 130.1 1.1 1.3 1 0 0 1 1 1 1 Fcf1 PilI PF10623.4 EDO06594.1 - 0.025 14.5 0.8 0.046 13.6 0.4 1.6 1 1 0 1 1 1 0 Plasmid conjugative transfer protein PilI DUF842 PF05811.8 EDO06595.1 - 3e-30 104.3 5.3 3.7e-30 104.0 3.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Histone PF00125.19 EDO06596.1 - 5.7e-22 77.6 0.1 7.3e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDO06596.1 - 0.00029 20.8 0.0 0.00041 20.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TRAPP PF04051.11 EDO06597.1 - 1.7e-28 99.0 0.0 1.9e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DEAD PF00270.24 EDO06598.1 - 2.9e-40 137.5 0.0 4e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO06598.1 - 1.9e-23 82.0 0.4 3.6e-23 81.2 0.1 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA PF00004.24 EDO06598.1 - 0.073 13.2 0.0 0.31 11.2 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2559 PF10832.3 EDO06598.1 - 0.097 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) zf-RING_2 PF13639.1 EDO06600.1 - 2.9e-13 49.4 5.4 4.5e-13 48.8 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDO06600.1 - 5.4e-10 39.2 5.1 1.5e-09 37.8 3.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDO06600.1 - 1.1e-07 31.3 4.5 1.8e-07 30.6 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO06600.1 - 9.3e-07 28.4 4.3 1.5e-06 27.8 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDO06600.1 - 1.8e-06 27.8 5.3 2.9e-06 27.1 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO06600.1 - 6.7e-06 25.6 2.6 1.1e-05 24.9 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EDO06600.1 - 0.00097 19.1 6.5 0.00097 19.1 4.5 1.5 2 0 0 2 2 1 1 RING-variant domain zf-Apc11 PF12861.2 EDO06600.1 - 0.002 17.8 3.9 0.0056 16.5 2.7 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EDO06600.1 - 0.033 13.6 1.0 0.067 12.7 0.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-PHD-like PF15446.1 EDO06600.1 - 0.044 13.0 2.9 0.085 12.1 2.0 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-RING_UBOX PF13445.1 EDO06600.1 - 0.24 11.1 2.1 1.7 8.4 1.4 2.3 1 1 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 EDO06600.1 - 0.29 10.8 4.3 0.56 9.9 3.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-P11 PF03854.9 EDO06600.1 - 2.3 7.7 4.7 4.7 6.7 3.3 1.5 1 1 0 1 1 1 0 P-11 zinc finger FANCL_C PF11793.3 EDO06600.1 - 2.9 7.9 6.6 9.2 6.3 4.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain TSP_1 PF00090.14 EDO06601.1 - 0.00027 20.9 32.4 0.019 15.0 0.1 6.0 5 0 0 5 5 5 3 Thrombospondin type 1 domain Pox_Ag35 PF03286.9 EDO06601.1 - 2.9 7.3 10.0 5.9 6.3 6.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cg6151-P PF10233.4 EDO06603.1 - 1.3 9.0 7.7 4.9 7.1 1.4 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein CG6151-P DUF2427 PF10348.4 EDO06603.1 - 1.3 8.6 5.5 0.71 9.4 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) TSP_1 PF00090.14 EDO06604.1 - 3.5e-08 33.4 17.2 0.00042 20.3 4.9 4.2 3 0 0 3 3 3 3 Thrombospondin type 1 domain DnaJ PF00226.26 EDO06606.1 - 1.9e-27 94.7 1.1 3.1e-27 94.0 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EDO06606.1 - 8.6e-26 89.6 0.2 3.4e-21 74.9 0.0 2.9 2 1 0 2 2 2 2 DnaJ C terminal domain Leu_Phe_trans PF03588.9 EDO06608.1 - 2.3e-32 111.5 0.2 3.4e-32 110.9 0.1 1.2 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase Acetyltransf_6 PF13480.1 EDO06608.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HJURP_C PF12347.3 EDO06608.1 - 0.062 12.8 0.3 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat s48_45 PF07422.8 EDO06610.1 - 1.2e-24 86.6 0.2 1.1e-13 51.2 0.0 2.8 3 0 0 3 3 3 2 Sexual stage antigen s48/45 domain s48_45 PF07422.8 EDO06611.1 - 1.3e-23 83.2 15.3 1.2e-15 57.5 3.0 2.8 3 0 0 3 3 3 2 Sexual stage antigen s48/45 domain s48_45 PF07422.8 EDO06612.1 - 6.1e-22 77.8 8.3 1.1e-13 51.3 3.5 2.5 2 0 0 2 2 2 2 Sexual stage antigen s48/45 domain s48_45 PF07422.8 EDO06613.1 - 4.1e-30 104.2 0.8 3.7e-14 52.7 0.0 3.4 3 0 0 3 3 3 3 Sexual stage antigen s48/45 domain s48_45 PF07422.8 EDO06614.1 - 5.3e-31 107.0 7.9 1.4e-15 57.3 0.5 3.1 3 0 0 3 3 3 2 Sexual stage antigen s48/45 domain KH_1 PF00013.24 EDO06615.1 - 0.0003 20.3 0.9 0.00069 19.2 0.6 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EDO06615.1 - 0.031 13.9 0.0 0.078 12.6 0.0 1.8 1 0 0 1 1 1 0 KH domain KH_4 PF13083.1 EDO06615.1 - 0.062 12.9 0.1 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 KH domain BRF1 PF07741.8 EDO06615.1 - 5.1 7.3 13.0 1.4e+02 2.7 9.0 2.5 1 1 0 1 1 1 0 Brf1-like TBP-binding domain SNARE PF05739.14 EDO06616.1 - 0.0081 15.8 0.2 0.0081 15.8 0.1 2.5 3 0 0 3 3 3 1 SNARE domain Laminin_I PF06008.9 EDO06616.1 - 0.0097 15.2 3.0 0.024 13.9 1.1 2.2 1 1 0 1 1 1 1 Laminin Domain I DUF3375 PF11855.3 EDO06616.1 - 0.011 14.4 0.6 0.014 14.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3375) RNA_pol PF00940.14 EDO06616.1 - 0.012 14.1 0.5 0.016 13.6 0.3 1.5 1 1 0 1 1 1 0 DNA-dependent RNA polymerase DUF2935 PF11155.3 EDO06616.1 - 0.041 13.9 0.6 0.089 12.8 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF1176 PF06674.6 EDO06616.1 - 0.058 12.4 1.8 0.076 12.1 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Syntaxin-6_N PF09177.6 EDO06616.1 - 0.48 10.8 3.7 0.73 10.2 0.7 2.6 1 1 3 4 4 4 0 Syntaxin 6, N-terminal AATF-Che1 PF13339.1 EDO06616.1 - 1.5 9.0 6.8 1.5 8.9 0.5 2.3 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor MCPsignal PF00015.16 EDO06616.1 - 6.6 6.2 12.9 5.6 6.4 2.6 2.5 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Ribosomal_L22 PF00237.14 EDO06617.1 - 4.8e-15 55.3 0.1 7.8e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Na_H_Exchanger PF00999.16 EDO06618.1 - 1.7e-08 33.3 10.1 2.5e-08 32.8 7.0 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3816 PF12822.2 EDO06618.1 - 0.071 13.0 11.7 0.24 11.2 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) DUF368 PF04018.8 EDO06618.1 - 0.073 12.2 6.0 0.04 13.1 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF368) DUF2324 PF10086.4 EDO06618.1 - 0.17 11.0 3.1 1.2 8.2 0.5 2.2 2 0 0 2 2 2 0 Putative membrane peptidase family (DUF2324) DUF2955 PF11168.3 EDO06618.1 - 2.8 7.5 10.3 2 8.0 1.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2955) zf-met PF12874.2 EDO06621.1 - 2.1e-05 24.5 0.5 2.1e-05 24.5 0.3 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 EDO06621.1 - 0.011 15.2 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein DnaJ PF00226.26 EDO06622.1 - 1e-17 63.6 0.3 3.8e-17 61.7 0.1 2.1 1 1 1 2 2 2 1 DnaJ domain Thioredoxin PF00085.15 EDO06622.1 - 2.9e-05 23.6 0.0 5.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Viral_Beta_CD PF04530.7 EDO06622.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Viral Beta C/D like family NTP_transferase PF00483.18 EDO06623.1 - 7.5e-47 159.7 0.0 9.3e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EDO06623.1 - 2.4e-12 45.7 11.9 9.8e-06 24.8 2.1 4.6 2 2 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EDO06623.1 - 2.1e-09 37.6 0.0 2.8e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EDO06623.1 - 3e-05 23.4 9.7 0.0051 16.3 3.2 3.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 EDO06623.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase UQ_con PF00179.21 EDO06624.1 - 1.8e-25 89.0 0.0 2.3e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO06624.1 - 1.8e-07 30.9 0.0 4.1e-07 29.8 0.0 1.5 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EDO06624.1 - 0.011 15.5 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 EDO06624.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain MACPF PF01823.14 EDO06625.1 - 1.2e-10 41.4 0.1 1.2e-10 41.4 0.1 3.1 2 1 0 3 3 3 1 MAC/Perforin domain DUF778 PF05608.7 EDO06625.1 - 0.021 14.7 0.7 0.072 13.0 0.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF778) TMEM219 PF14940.1 EDO06625.1 - 0.36 9.8 2.9 1.7 7.6 0.3 2.7 2 1 0 3 3 3 0 Transmembrane 219 Adap_comp_sub PF00928.16 EDO06626.1 - 5.5e-56 189.5 0.0 7.3e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EDO06626.1 - 0.0024 17.5 0.1 0.0042 16.8 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain VESA1_N PF12785.2 EDO06628.1 - 6.3e-218 724.3 16.7 6.3e-218 724.3 11.6 2.7 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 DUF4398 PF14346.1 EDO06628.1 - 0.49 10.4 3.5 0.3 11.1 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Baculo_PEP_C PF04513.7 EDO06628.1 - 5.4 6.8 7.9 2.9 7.7 0.9 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus VESA1_N PF12785.2 EDO06629.1 - 9.4e-23 80.8 12.4 9.4e-23 80.8 8.6 5.1 5 1 1 6 6 6 2 Variant erythrocyte surface antigen-1 F-box-like_2 PF13013.1 EDO06630.1 - 0.0042 16.7 0.1 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 F-box-like domain F-box-like_2 PF13013.1 EDO06631.1 - 2.9e-07 30.1 0.1 0.023 14.3 0.0 2.5 1 1 1 2 2 2 2 F-box-like domain Band_7 PF01145.20 EDO06631.1 - 0.0071 16.2 0.0 0.51 10.2 0.0 2.1 1 1 1 2 2 2 2 SPFH domain / Band 7 family DUF2076 PF09849.4 EDO06631.1 - 0.072 13.1 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Malate_DH PF12434.3 EDO06631.1 - 5.7 6.7 5.4 12 5.6 0.2 3.2 3 0 0 3 3 3 0 Malate dehydrogenase enzyme VESA1_N PF12785.2 EDO06632.1 - 2.4e-20 72.9 16.0 2e-11 43.5 0.0 3.2 1 1 1 2 2 2 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO06633.1 - 1.4e-214 713.3 19.3 1.4e-214 713.3 13.4 2.9 4 0 0 4 4 4 1 Variant erythrocyte surface antigen-1 Baculo_PEP_C PF04513.7 EDO06633.1 - 1.2 8.9 4.8 57 3.5 0.1 3.9 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1978 PF09321.5 EDO06633.1 - 1.6 8.1 7.4 0.58 9.5 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1978) Syntaxin-6_N PF09177.6 EDO06633.1 - 6.9 7.1 7.2 8.7 6.8 0.1 3.2 3 1 0 3 3 3 0 Syntaxin 6, N-terminal GTPase_Cys_C PF12631.2 EDO06633.1 - 8.4 6.8 6.3 11 6.5 0.1 4.0 5 0 0 5 5 5 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Abhydrolase_6 PF12697.2 EDO06634.1 - 9.4e-31 107.4 0.0 5e-30 105.0 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO06634.1 - 8.5e-23 80.7 0.2 2.3e-22 79.3 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO06634.1 - 2.4e-19 69.7 0.0 3.3e-16 59.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EDO06634.1 - 1.8e-07 30.8 0.3 3.5e-07 29.9 0.2 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EDO06634.1 - 6.4e-06 24.8 0.0 1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family DLH PF01738.13 EDO06634.1 - 6.8e-06 25.5 0.0 0.01 15.1 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EDO06634.1 - 3.8e-05 23.3 0.0 0.00023 20.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDO06634.1 - 9e-05 21.7 0.0 0.023 13.9 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.8 EDO06634.1 - 0.00063 19.2 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2305 PF10230.4 EDO06634.1 - 0.0013 18.2 0.0 0.006 16.0 0.0 2.0 1 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 EDO06634.1 - 0.0045 16.4 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_4 PF08386.5 EDO06634.1 - 0.0054 16.6 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.6 EDO06634.1 - 0.0057 16.3 0.0 0.019 14.6 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 EDO06634.1 - 0.026 13.9 0.0 0.86 8.9 0.0 2.7 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.2 EDO06634.1 - 0.081 11.8 0.0 0.24 10.2 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase enzyme WD40 PF00400.27 EDO06636.1 - 1.4e-15 56.4 8.9 0.00048 19.8 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40 PF00400.27 EDO06637.1 - 2.4e-38 128.6 8.2 1.8e-06 27.6 0.1 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Utp13 PF08625.6 EDO06637.1 - 1.5e-31 108.9 0.2 2.9e-31 108.0 0.2 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.27 EDO06638.1 - 6.7e-20 70.1 2.2 8e-06 25.5 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.1 EDO06638.1 - 0.04 14.1 3.5 36 4.7 0.0 5.4 7 0 0 7 7 7 0 PQQ-like domain PQQ PF01011.16 EDO06638.1 - 0.21 11.1 2.5 7 6.3 0.0 3.9 5 0 0 5 5 5 0 PQQ enzyme repeat Pkinase PF00069.20 EDO06639.1 - 1.3e-51 175.2 0.0 9.1e-41 139.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO06639.1 - 1e-27 96.8 0.0 3.4e-22 78.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDO06639.1 - 0.0068 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO06639.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EDO06639.1 - 0.16 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Flavoprotein PF02441.14 EDO06640.1 - 2.4e-41 140.4 0.0 2.9e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Snf7 PF03357.16 EDO06641.1 - 3.3e-17 62.3 9.7 4.2e-17 62.0 6.7 1.1 1 0 0 1 1 1 1 Snf7 DUF3336 PF11815.3 EDO06641.1 - 0.008 15.6 2.7 0.015 14.7 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Peptidase_S46 PF10459.4 EDO06641.1 - 0.019 13.4 3.8 0.023 13.1 2.6 1.1 1 0 0 1 1 1 0 Peptidase S46 RIX1 PF08167.7 EDO06641.1 - 0.07 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis Citrate_synt PF00285.16 EDO06642.1 - 8.4e-98 327.3 0.0 9.9e-98 327.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase GcpE PF04551.9 EDO06643.1 - 4.6e-157 522.4 0.0 2e-156 520.3 0.0 1.8 1 1 0 1 1 1 1 GcpE protein zf-HYPF PF07503.7 EDO06643.1 - 0.083 12.3 0.1 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 HypF finger zf-CDGSH PF09360.5 EDO06644.1 - 2.3e-22 78.5 10.0 1.7e-14 53.3 1.1 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Acyltransferase PF01553.16 EDO06645.1 - 3.1e-15 55.7 0.0 4.7e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase VPS9 PF02204.13 EDO06646.1 - 4.8e-26 90.8 0.0 9e-26 89.9 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CAF1C_H4-bd PF12265.3 EDO06647.1 - 2.2e-19 69.1 0.0 4.5e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 EDO06647.1 - 4.1e-18 64.5 17.8 7.2e-07 28.8 0.6 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF3312 PF11768.3 EDO06647.1 - 0.0036 15.5 0.1 0.0095 14.2 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3312) Clathrin_propel PF01394.15 EDO06647.1 - 0.023 14.9 0.0 0.46 10.8 0.0 2.8 3 0 0 3 3 3 0 Clathrin propeller repeat PX PF00787.19 EDO06648.1 - 1e-06 28.4 0.0 2.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 PX domain WD40 PF00400.27 EDO06648.1 - 0.0013 18.5 0.4 0.96 9.4 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat Enterotoxin_a PF01375.12 EDO06648.1 - 0.031 13.5 0.1 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain MFS_1 PF07690.11 EDO06649.1 - 6.7e-07 28.3 17.8 1.8e-06 26.9 12.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EDO06650.1 - 4.6e-13 48.6 21.1 6.7e-13 48.0 14.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EDO06650.1 - 0.036 12.4 30.8 0.02 13.2 4.3 2.6 1 1 1 2 2 2 0 MFS/sugar transport protein Spc97_Spc98 PF04130.8 EDO06651.1 - 5.6e-58 196.5 1.6 3.4e-57 193.9 1.1 1.9 1 1 0 1 1 1 1 Spc97 / Spc98 family CAF1 PF04857.15 EDO06652.1 - 2.4e-62 210.6 0.1 3.2e-62 210.2 0.1 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.6 EDO06652.1 - 0.00043 20.2 0.1 0.0012 18.7 0.1 1.7 1 0 0 1 1 1 1 RNA binding domain DUF2826 PF11442.3 EDO06653.1 - 0.051 13.2 0.2 0.079 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) SPT16 PF08644.6 EDO06653.1 - 6.9 6.4 10.0 22 4.8 6.9 1.9 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) eIF-5_eIF-2B PF01873.12 EDO06654.1 - 4.7e-34 116.7 0.3 1.1e-33 115.4 0.1 1.6 1 1 1 2 2 2 1 Domain found in IF2B/IF5 zf-RanBP PF00641.13 EDO06654.1 - 0.3 10.2 2.2 3.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Ribosomal_L28 PF00830.14 EDO06656.1 - 1.2e-18 66.6 6.6 2.2e-18 65.8 1.2 2.7 3 0 0 3 3 3 2 Ribosomal L28 family GHMP_kinases_C PF08544.8 EDO06657.1 - 0.0023 18.0 0.0 0.005 17.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EDO06657.1 - 0.013 15.5 4.0 0.015 15.3 0.4 2.3 2 0 0 2 2 2 0 GHMP kinases N terminal domain PPR_2 PF13041.1 EDO06658.1 - 0.0086 16.0 0.2 0.038 13.9 0.0 2.0 2 0 0 2 2 2 1 PPR repeat family Exonuc_VII_L PF02601.10 EDO06658.1 - 0.044 12.9 1.3 0.09 11.9 0.0 1.8 1 1 1 2 2 2 0 Exonuclease VII, large subunit PDGF_N PF04692.8 EDO06658.1 - 0.066 13.7 1.8 0.1 13.1 0.0 2.1 2 1 0 2 2 2 0 Platelet-derived growth factor, N terminal region AAA PF00004.24 EDO06659.1 - 9.5e-07 29.0 0.0 3.7e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDO06659.1 - 1.8e-05 24.7 0.0 5.3e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDO06659.1 - 0.00024 21.2 0.0 0.00059 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO06659.1 - 0.002 17.8 0.0 0.0065 16.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EDO06659.1 - 0.002 17.1 0.0 0.0026 16.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 EDO06659.1 - 0.0043 16.0 0.1 0.012 14.6 0.0 1.6 2 0 0 2 2 2 1 PIF1-like helicase NACHT PF05729.7 EDO06659.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.6 1 1 0 1 1 1 1 NACHT domain ArgK PF03308.11 EDO06659.1 - 0.032 13.0 0.3 4.8 5.8 0.0 2.3 2 0 0 2 2 2 0 ArgK protein T2SE PF00437.15 EDO06659.1 - 0.057 12.3 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EDO06659.1 - 0.07 12.8 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 EDO06659.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DNA_pol_B_palm PF14792.1 EDO06660.1 - 0.013 15.5 2.6 0.043 13.8 0.1 2.9 3 0 0 3 3 3 0 DNA polymerase beta palm MRP-L27 PF09809.4 EDO06661.1 - 4.7e-11 42.2 0.0 5.5e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 AP2 PF00847.15 EDO06662.1 - 7.7e-07 29.1 2.9 0.00022 21.3 0.2 2.7 2 0 0 2 2 2 2 AP2 domain RcsC PF09456.5 EDO06662.1 - 0.11 12.1 0.1 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) XRN_N PF03159.13 EDO06664.1 - 6.9e-83 277.6 0.0 1.3e-82 276.7 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus MACPF PF01823.14 EDO06665.1 - 1.8e-33 116.0 0.3 1.8e-33 116.0 0.2 2.0 2 0 0 2 2 2 1 MAC/Perforin domain PI31_Prot_C PF08577.6 EDO06665.1 - 0.036 14.6 0.5 18 6.0 0.0 2.8 2 0 0 2 2 2 0 PI31 proteasome regulator KIF1B PF12423.3 EDO06665.1 - 0.17 11.9 13.3 4.8 7.3 0.4 3.8 3 0 0 3 3 3 0 Kinesin protein 1B tRNA-synt_2d PF01409.15 EDO06667.1 - 1e-35 123.0 0.4 2.7e-19 69.3 0.0 3.1 2 1 1 3 3 3 3 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EDO06667.1 - 8.7e-17 61.0 0.0 2.7e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 EDO06667.1 - 0.0059 15.4 0.1 0.2 10.3 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) Motilin_ghrelin PF04644.7 EDO06667.1 - 0.14 11.9 0.3 0.32 10.8 0.2 1.6 1 0 0 1 1 1 0 Motilin/ghrelin C2 PF00168.25 EDO06668.1 - 3.2e-09 36.4 0.1 1.5e-06 27.9 0.0 2.8 2 0 0 2 2 2 2 C2 domain DHO_dh PF01180.16 EDO06669.1 - 6.3e-87 291.2 0.4 7.4e-87 291.0 0.3 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.10 EDO06669.1 - 0.0052 15.9 0.0 0.0098 15.0 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase PcrB PF01884.12 EDO06669.1 - 0.04 13.1 0.6 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 PcrB family DeoC PF01791.4 EDO06669.1 - 0.04 13.2 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase AAA PF00004.24 EDO06670.1 - 1.9e-53 180.1 0.0 1.4e-38 132.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO06670.1 - 4.3e-12 46.3 2.4 0.00072 19.6 0.4 4.9 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.9 EDO06670.1 - 7.5e-12 45.1 0.0 6.8e-06 25.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_N PF02359.13 EDO06670.1 - 4.1e-10 39.4 0.0 1.2e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_16 PF13191.1 EDO06670.1 - 1.2e-09 38.4 0.2 0.00043 20.3 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EDO06670.1 - 1.9e-09 38.3 0.0 0.00043 21.1 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_2 PF07724.9 EDO06670.1 - 2e-08 34.3 0.0 1.8e-06 27.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EDO06670.1 - 2.3e-08 33.9 0.0 0.0029 17.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EDO06670.1 - 1e-07 31.9 0.0 0.0017 18.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EDO06670.1 - 1.9e-07 30.1 0.0 0.011 14.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Arch_ATPase PF01637.13 EDO06670.1 - 2e-06 27.6 0.1 2.6 7.6 0.0 4.1 2 2 1 4 4 4 1 Archaeal ATPase RNA_helicase PF00910.17 EDO06670.1 - 2.9e-06 27.4 0.0 0.013 15.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 EDO06670.1 - 3.1e-06 26.4 0.0 0.0051 15.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EDO06670.1 - 4e-06 27.1 0.0 0.00091 19.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDO06670.1 - 1.1e-05 25.0 0.4 0.055 13.2 0.0 2.8 3 0 0 3 3 2 2 Part of AAA domain RuvB_N PF05496.7 EDO06670.1 - 1.5e-05 24.1 0.1 0.058 12.4 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EDO06670.1 - 1.7e-05 24.5 0.3 0.22 11.1 0.0 3.3 3 1 0 3 3 3 2 NACHT domain AAA_28 PF13521.1 EDO06670.1 - 2.9e-05 24.0 0.0 0.019 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EDO06670.1 - 0.00011 21.6 0.0 0.53 9.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EDO06670.1 - 0.00018 21.0 0.1 0.035 13.5 0.0 2.9 3 1 1 4 4 3 1 AAA domain NB-ARC PF00931.17 EDO06670.1 - 0.00018 20.4 0.0 1.3 7.8 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain IstB_IS21 PF01695.12 EDO06670.1 - 0.0005 19.5 0.0 0.16 11.3 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.22 EDO06670.1 - 0.00055 20.2 0.1 0.27 11.5 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Parvo_NS1 PF01057.12 EDO06670.1 - 0.00068 18.5 0.0 0.18 10.6 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 EDO06670.1 - 0.00075 18.6 0.1 0.23 10.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 EDO06670.1 - 0.00083 18.9 0.1 0.019 14.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EDO06670.1 - 0.00098 17.9 0.2 0.71 8.4 0.0 2.6 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein KaiC PF06745.8 EDO06670.1 - 0.0016 17.6 0.0 0.017 14.2 0.0 2.2 2 0 0 2 2 2 1 KaiC SKI PF01202.17 EDO06670.1 - 0.0044 16.8 0.0 0.45 10.3 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase DUF2075 PF09848.4 EDO06670.1 - 0.0048 15.9 0.1 0.01 14.8 0.0 1.5 2 0 0 2 2 1 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 EDO06670.1 - 0.0068 16.0 0.0 0.061 12.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EDO06670.1 - 0.007 16.4 0.1 1.6 8.7 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AFG1_ATPase PF03969.11 EDO06670.1 - 0.0073 15.1 0.0 1.6 7.4 0.0 2.3 2 0 0 2 2 2 1 AFG1-like ATPase DAP3 PF10236.4 EDO06670.1 - 0.013 14.4 0.0 0.51 9.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 UPF0079 PF02367.12 EDO06670.1 - 0.013 15.0 0.1 0.97 9.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EDO06670.1 - 0.014 14.6 0.0 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF815 PF05673.8 EDO06670.1 - 0.016 14.1 0.0 0.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DNA_pol3_delta2 PF13177.1 EDO06670.1 - 0.019 14.6 0.0 0.14 11.8 0.0 2.4 3 1 0 3 3 2 0 DNA polymerase III, delta subunit ATP-synt_ab PF00006.20 EDO06670.1 - 0.056 12.9 0.0 0.39 10.1 0.0 2.2 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain CDC48_2 PF02933.12 EDO06670.1 - 0.061 12.9 0.1 0.32 10.6 0.0 2.2 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 AAA_11 PF13086.1 EDO06670.1 - 0.085 12.4 0.0 0.9 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EDO06670.1 - 0.094 11.9 0.0 0.41 9.7 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 EDO06670.1 - 0.12 11.9 0.2 11 5.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_PrkA PF08298.6 EDO06670.1 - 0.12 11.0 0.0 1.8 7.1 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_30 PF13604.1 EDO06670.1 - 0.17 11.4 0.0 1.7 8.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain CRM1_C PF08767.6 EDO06672.1 - 2.9e-127 424.0 3.3 2.9e-127 424.0 2.3 2.9 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EDO06672.1 - 1.4e-33 115.9 1.5 1.4e-33 115.9 1.0 3.4 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EDO06672.1 - 2e-08 34.0 0.2 5.4e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Pkinase PF00069.20 EDO06673.1 - 7.2e-49 166.2 0.4 2.4e-48 164.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO06673.1 - 7.5e-19 67.7 0.0 1.6e-17 63.4 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase TYW3 PF02676.9 EDO06674.1 - 6.2e-36 123.4 0.0 1e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 PHF5 PF03660.9 EDO06675.1 - 5.2e-46 155.1 14.7 1.6e-45 153.5 10.2 1.8 1 0 0 1 1 1 1 PHF5-like protein GTP_EFTU PF00009.22 EDO06675.1 - 2.1e-30 105.5 0.0 1.5e-29 102.7 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EDO06675.1 - 1.6e-19 69.8 0.2 4.3e-19 68.4 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EDO06675.1 - 1.4e-14 53.9 2.8 5.4e-09 36.0 0.4 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EDO06675.1 - 4.6e-07 29.3 0.2 1.4e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EDO06675.1 - 5e-05 23.2 0.0 0.0003 20.7 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EDO06675.1 - 0.0059 16.1 0.0 0.036 13.6 0.0 2.3 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein DUF4225 PF13988.1 EDO06675.1 - 0.029 13.8 0.1 0.65 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) AAA_16 PF13191.1 EDO06675.1 - 0.22 11.5 3.0 0.57 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain zf-RING_2 PF13639.1 EDO06676.1 - 6.8e-13 48.2 6.3 6.8e-13 48.2 4.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EDO06676.1 - 7.7e-08 32.3 1.6 1.8e-07 31.1 1.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EDO06676.1 - 4.3e-06 26.3 2.9 4.3e-06 26.3 2.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO06676.1 - 1.4e-05 25.0 6.9 1.4e-05 25.0 4.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO06676.1 - 1.8e-05 24.3 3.2 1.8e-05 24.3 2.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain RINGv PF12906.2 EDO06676.1 - 0.001 19.0 5.2 0.001 19.0 3.6 1.9 2 0 0 2 2 2 1 RING-variant domain zf-C3HC4 PF00097.20 EDO06676.1 - 0.0045 16.6 4.4 0.0045 16.6 3.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EDO06676.1 - 0.017 15.0 1.3 0.017 15.0 0.9 2.0 2 1 0 2 2 2 0 FANCL C-terminal domain zf-Apc11 PF12861.2 EDO06676.1 - 0.043 13.6 4.9 0.23 11.3 3.4 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 EDO06676.1 - 0.12 11.5 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Baculo_RING PF05883.6 EDO06676.1 - 0.16 11.7 2.2 0.38 10.5 1.6 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain ABC_membrane PF00664.18 EDO06676.1 - 0.22 10.8 2.4 0.35 10.2 1.6 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region EXS PF03124.9 EDO06677.1 - 1.4e-69 234.7 23.0 2e-69 234.2 16.0 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EDO06677.1 - 9.8e-14 51.7 1.9 1.8e-06 27.9 0.0 2.3 2 1 0 2 2 2 2 SPX domain WD40 PF00400.27 EDO06678.1 - 5.3e-08 32.4 1.8 0.00027 20.7 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat IncA PF04156.9 EDO06680.1 - 0.0004 20.0 0.7 0.00063 19.3 0.1 1.7 2 1 0 2 2 2 1 IncA protein Fez1 PF06818.10 EDO06680.1 - 0.0054 16.7 2.8 0.008 16.2 1.8 1.4 1 1 0 1 1 1 1 Fez1 TMV_coat PF00721.16 EDO06680.1 - 0.026 14.4 0.6 0.074 12.9 0.0 1.9 1 1 1 2 2 2 0 Virus coat protein (TMV like) DUF4407 PF14362.1 EDO06680.1 - 0.047 12.6 2.2 0.14 11.0 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.5 EDO06680.1 - 0.049 13.7 6.9 1.8 8.7 0.2 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2951 PF11166.3 EDO06680.1 - 0.41 10.5 8.6 0.36 10.6 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) CorA PF01544.13 EDO06680.1 - 0.91 8.5 7.4 0.26 10.2 3.0 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4164 PF13747.1 EDO06680.1 - 1.2 9.3 12.8 0.25 11.4 4.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) GYF PF02213.11 EDO06681.1 - 3.1e-15 55.4 4.7 8.3e-15 54.1 3.3 1.8 1 0 0 1 1 1 1 GYF domain KOW PF00467.24 EDO06682.1 - 2.2e-05 23.9 2.3 4.6e-05 22.9 1.6 1.5 1 0 0 1 1 1 1 KOW motif TAXi_C PF14541.1 EDO06684.1 - 0.0084 15.6 0.0 0.025 14.1 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Glutaredoxin PF00462.19 EDO06686.1 - 5.1e-19 68.0 0.0 1.5e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EDO06686.1 - 0.00049 19.7 0.0 0.00097 18.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin ArsC PF03960.10 EDO06686.1 - 0.016 15.2 0.0 0.049 13.6 0.0 1.7 2 0 0 2 2 2 0 ArsC family GST_N_3 PF13417.1 EDO06686.1 - 0.025 14.7 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.1 EDO06686.1 - 0.031 14.4 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain SH3BGR PF04908.10 EDO06686.1 - 0.052 13.5 0.0 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein GST_N_2 PF13409.1 EDO06686.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Methyltransf_23 PF13489.1 EDO06687.1 - 1.3e-18 67.2 0.0 1.8e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO06687.1 - 4.1e-18 65.4 0.1 5.9e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO06687.1 - 2.1e-15 56.9 0.0 4.4e-15 55.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO06687.1 - 1.5e-14 54.5 0.0 2.7e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO06687.1 - 2.6e-14 53.5 0.1 9.5e-14 51.6 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO06687.1 - 1.5e-12 47.7 0.0 2.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO06687.1 - 5.5e-07 29.6 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDO06687.1 - 2.7e-06 26.6 0.2 1.5e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 EDO06687.1 - 4.3e-05 22.9 1.3 0.0041 16.5 0.9 2.2 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EDO06687.1 - 8.1e-05 22.0 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EDO06687.1 - 0.00011 21.4 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EDO06687.1 - 0.00046 19.8 0.0 0.00097 18.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDO06687.1 - 0.00097 18.7 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.6 EDO06687.1 - 0.0013 18.1 0.2 0.076 12.4 0.1 2.1 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 EDO06687.1 - 0.0016 17.1 0.0 0.0026 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.9 EDO06687.1 - 0.01 14.9 0.0 0.019 14.1 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.15 EDO06687.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TPMT PF05724.6 EDO06687.1 - 0.065 12.6 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) AdoMet_MTase PF07757.8 EDO06687.1 - 0.087 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Cyclin_N PF00134.18 EDO06688.1 - 8.3e-12 44.7 0.7 1.7e-11 43.7 0.5 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.20 EDO06689.1 - 8.9e-46 156.1 0.1 1.2e-45 155.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO06689.1 - 9.2e-27 93.7 0.0 1.3e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDO06689.1 - 1e-06 27.9 0.1 1.8e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TAXi_C PF14541.1 EDO06691.1 - 0.013 15.0 0.0 0.035 13.6 0.0 1.8 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal SmpB PF01668.13 EDO06692.1 - 0.12 12.2 0.3 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 SmpB protein PIP49_C PF12260.3 EDO06692.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Glutaredoxin PF00462.19 EDO06693.1 - 4.9e-19 68.0 0.0 1.5e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EDO06693.1 - 0.00026 20.6 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin ArsC PF03960.10 EDO06693.1 - 0.016 15.2 0.0 0.049 13.6 0.0 1.7 2 0 0 2 2 2 0 ArsC family GST_N_3 PF13417.1 EDO06693.1 - 0.025 14.7 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.1 EDO06693.1 - 0.027 14.6 0.0 0.24 11.5 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain SH3BGR PF04908.10 EDO06693.1 - 0.051 13.5 0.0 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein GST_N_2 PF13409.1 EDO06693.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Methyltransf_23 PF13489.1 EDO06694.1 - 6.2e-24 84.5 0.0 1.3e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO06694.1 - 2.3e-19 69.4 0.0 3.7e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO06694.1 - 3.8e-17 62.5 0.3 1.2e-16 60.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO06694.1 - 6.6e-17 62.0 0.2 4.1e-16 59.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO06694.1 - 1.3e-14 54.4 0.6 5e-14 52.5 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain PDCD2_C PF04194.8 EDO06694.1 - 1.2e-12 47.7 0.0 1.9e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Methyltransf_25 PF13649.1 EDO06694.1 - 1.5e-12 47.7 0.0 3.7e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO06694.1 - 3.2e-09 36.8 0.0 6.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDO06694.1 - 1.1e-07 31.2 0.1 4.5e-07 29.2 0.1 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EDO06694.1 - 2.2e-05 23.7 0.1 3.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EDO06694.1 - 0.00041 19.5 0.0 0.00082 18.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 EDO06694.1 - 0.00042 19.7 0.0 0.014 14.8 0.0 2.2 1 1 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 EDO06694.1 - 0.0005 19.5 0.0 0.00093 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EDO06694.1 - 0.00065 19.3 0.1 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 EDO06694.1 - 0.00071 18.3 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 EDO06694.1 - 0.00077 19.1 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EDO06694.1 - 0.00078 18.8 1.3 0.038 13.3 0.9 2.2 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.6 EDO06694.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.15 EDO06694.1 - 0.022 13.7 0.0 0.048 12.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.9 EDO06694.1 - 0.067 12.3 0.1 0.2 10.7 0.0 1.8 1 1 0 1 1 1 0 Tellurite resistance protein TehB Pox_MCEL PF03291.11 EDO06694.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme ADH_zinc_N PF00107.21 EDO06694.1 - 0.12 11.8 0.1 0.75 9.3 0.0 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Topoisom_I PF01028.15 EDO06695.1 - 8.6e-95 316.3 1.7 1.9e-94 315.1 1.2 1.6 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.10 EDO06695.1 - 7e-80 267.3 1.3 7e-80 267.3 0.9 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.1 EDO06695.1 - 5.5e-33 112.4 0.2 1.7e-32 110.8 0.2 1.9 1 0 0 1 1 1 1 C-terminal topoisomerase domain Bromodomain PF00439.20 EDO06696.1 - 7.9e-13 48.1 0.1 2.4e-12 46.5 0.1 1.8 1 0 0 1 1 1 1 Bromodomain PIP5K PF01504.13 EDO06697.1 - 2.1e-74 249.8 0.0 3.4e-74 249.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_6 PF13405.1 EDO06697.1 - 3.2e-05 23.4 0.1 0.0025 17.5 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 EDO06697.1 - 3.2e-05 23.4 0.0 0.00035 20.1 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EDO06697.1 - 7.9e-05 21.8 0.0 0.00026 20.1 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 EDO06697.1 - 0.00036 19.6 0.0 0.0016 17.5 0.0 2.2 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EDO06697.1 - 0.00071 19.6 0.5 0.0051 16.9 0.0 2.6 3 1 0 3 3 3 1 EF-hand domain pair JAB PF01398.16 EDO06698.1 - 3.2e-32 110.6 0.0 6.3e-32 109.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EDO06698.1 - 1e-21 77.1 1.8 1.7e-21 76.4 1.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EDO06698.1 - 6.4e-10 38.5 0.0 1.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Zn_ribbon_recom PF13408.1 EDO06699.1 - 0.11 12.8 0.8 0.19 12.0 0.6 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain UPF0547 PF10571.4 EDO06699.1 - 0.14 11.8 0.5 0.14 11.8 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 TF_Zn_Ribbon PF08271.7 EDO06700.1 - 5.2e-08 32.0 0.4 1e-07 31.1 0.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIB PF00382.14 EDO06700.1 - 8.6e-05 22.2 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Transcription factor TFIIB repeat ArfGap PF01412.13 EDO06700.1 - 0.01 15.6 1.3 0.017 14.8 0.6 1.6 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DUF1283 PF06932.6 EDO06700.1 - 0.012 15.5 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) OrfB_Zn_ribbon PF07282.6 EDO06700.1 - 0.12 12.0 0.2 0.12 12.0 0.2 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain AAA_18 PF13238.1 EDO06701.1 - 2e-17 63.7 0.3 2.4e-17 63.4 0.2 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO06701.1 - 1.8e-12 48.1 0.3 2.2e-12 47.8 0.2 1.2 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EDO06701.1 - 1.4e-05 24.8 0.1 0.0018 18.0 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA PF00004.24 EDO06701.1 - 1.5e-05 25.2 0.0 2.1e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDO06701.1 - 5.3e-05 23.2 0.1 7.3e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 EDO06701.1 - 0.00017 21.5 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO06701.1 - 0.00099 19.2 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDO06701.1 - 0.0018 18.1 0.0 0.0092 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EDO06701.1 - 0.0025 17.0 0.0 0.0034 16.6 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ADK PF00406.17 EDO06701.1 - 0.003 17.4 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase RNA_helicase PF00910.17 EDO06701.1 - 0.0033 17.5 0.0 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 EDO06701.1 - 0.0052 16.5 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.1 EDO06701.1 - 0.0066 16.3 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Cytidylate kinase-like family RuvB_N PF05496.7 EDO06701.1 - 0.0079 15.2 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus SKI PF01202.17 EDO06701.1 - 0.012 15.5 0.0 0.1 12.4 0.0 2.1 1 1 0 1 1 1 0 Shikimate kinase AAA_19 PF13245.1 EDO06701.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_3 PF07726.6 EDO06701.1 - 0.028 14.0 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EDO06701.1 - 0.034 13.6 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EDO06701.1 - 0.034 13.8 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 EDO06701.1 - 0.042 12.8 0.0 0.042 12.8 0.0 1.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 EDO06701.1 - 0.06 12.4 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 EDO06701.1 - 0.063 12.9 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EDO06701.1 - 0.067 13.0 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EDO06701.1 - 0.096 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 EDO06701.1 - 0.098 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EDO06701.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Nol1_Nop2_Fmu PF01189.12 EDO06702.1 - 1.2e-27 97.0 0.0 4.3e-13 49.2 0.0 2.1 1 1 1 2 2 2 2 NOL1/NOP2/sun family Ubie_methyltran PF01209.13 EDO06702.1 - 4.2e-05 22.7 0.0 7.8e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EDO06702.1 - 0.00023 20.8 0.0 0.031 13.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO06702.1 - 0.0031 17.5 0.0 0.063 13.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDO06702.1 - 0.0057 16.0 0.0 0.045 13.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain RNA_POL_M_15KD PF02150.11 EDO06704.1 - 9.5e-09 34.8 2.8 3.3e-08 33.0 0.6 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 EDO06704.1 - 5.3e-08 32.3 1.2 5.3e-08 32.3 0.9 4.0 4 1 1 5 5 5 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 EDO06704.1 - 0.00026 21.2 5.3 0.00054 20.2 0.6 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar DZR PF12773.2 EDO06704.1 - 0.00067 19.4 0.7 0.061 13.1 0.2 2.5 2 0 0 2 2 2 1 Double zinc ribbon zf-CSL PF05207.8 EDO06704.1 - 0.049 13.1 0.5 0.049 13.1 0.4 2.5 2 1 0 2 2 2 0 CSL zinc finger IBR PF01485.16 EDO06704.1 - 0.05 13.4 4.1 1.7 8.5 0.2 3.0 3 0 0 3 3 3 0 IBR domain Zn_Tnp_IS1595 PF12760.2 EDO06704.1 - 0.053 13.3 7.0 0.39 10.5 0.0 3.0 3 1 0 3 3 3 0 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.1 EDO06704.1 - 0.13 12.5 3.0 0.23 11.7 0.1 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Elf1 PF05129.8 EDO06704.1 - 0.18 11.5 2.2 2.4 7.8 0.1 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-B_box PF00643.19 EDO06704.1 - 0.21 11.5 3.3 9.6 6.2 0.5 2.7 2 1 0 2 2 2 0 B-box zinc finger OrfB_Zn_ribbon PF07282.6 EDO06704.1 - 0.27 10.8 8.5 1.1 9.0 0.2 2.5 3 0 0 3 3 2 0 Putative transposase DNA-binding domain DUF2082 PF09855.4 EDO06704.1 - 0.34 10.7 3.8 16 5.4 0.0 3.1 2 1 1 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) RecR PF02132.10 EDO06704.1 - 0.38 10.2 4.9 0.55 9.7 0.0 3.1 3 0 0 3 3 3 0 RecR protein zinc_ribbon_2 PF13240.1 EDO06704.1 - 0.98 8.9 7.3 7.9 6.1 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Rubredoxin PF00301.15 EDO06704.1 - 1.1 9.1 7.5 0.93 9.4 0.2 3.4 3 0 0 3 3 3 0 Rubredoxin zf-ribbon_3 PF13248.1 EDO06704.1 - 1.9 7.8 11.3 1.6 8.0 0.1 2.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-RanBP PF00641.13 EDO06704.1 - 2.4 7.3 6.7 0.69 9.0 0.8 2.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Zn-ribbon_8 PF09723.5 EDO06704.1 - 3.9 7.5 8.2 12 5.9 0.1 3.7 4 0 0 4 4 4 0 Zinc ribbon domain Nudix_N_2 PF14803.1 EDO06704.1 - 7.6 6.3 9.0 49 3.7 0.1 3.3 2 1 0 2 2 2 0 Nudix N-terminal Evr1_Alr PF04777.8 EDO06705.1 - 6.6e-20 70.8 0.0 9.9e-20 70.2 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family PhaP_Bmeg PF09602.5 EDO06706.1 - 0.0022 17.8 5.8 0.0022 17.8 4.0 1.7 2 0 0 2 2 2 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) AcylCoA_dehyd_C PF12186.3 EDO06706.1 - 0.005 16.6 2.0 0.014 15.2 1.2 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase C terminal UQ_con PF00179.21 EDO06706.1 - 0.006 16.0 0.3 0.019 14.4 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Alpha_TIF PF02232.10 EDO06706.1 - 0.0092 14.8 0.3 0.013 14.3 0.2 1.2 1 0 0 1 1 1 1 Alpha trans-inducing protein (Alpha-TIF) UPF0262 PF06793.7 EDO06706.1 - 0.03 14.0 0.2 0.098 12.3 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0262) Mod_r PF07200.8 EDO06706.1 - 0.71 9.7 12.4 5.7 6.8 3.5 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CTP_transf_1 PF01148.15 EDO06708.1 - 3.9e-06 26.7 12.3 3.9e-06 26.7 8.5 3.0 1 1 2 3 3 3 1 Cytidylyltransferase family Sec23_trunk PF04811.10 EDO06709.1 - 2.5e-60 203.8 0.1 4.5e-60 203.0 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EDO06709.1 - 2.2e-34 117.8 0.2 2.2e-34 117.8 0.2 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 EDO06709.1 - 1.6e-31 107.8 1.5 3.2e-31 106.8 1.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EDO06709.1 - 1.4e-14 53.3 1.6 1.4e-14 53.3 1.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EDO06709.1 - 2.3e-09 36.8 0.0 6.6e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.1 EDO06709.1 - 0.0027 17.8 0.0 0.0085 16.2 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EDO06709.1 - 0.0046 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain LSM PF01423.17 EDO06710.1 - 7.1e-16 57.5 0.2 8.4e-16 57.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain UPF0121 PF03661.8 EDO06711.1 - 5.1e-10 38.9 2.9 5.1e-10 38.9 2.0 1.5 1 1 0 2 2 2 1 Uncharacterised protein family (UPF0121) FNIP PF05725.7 EDO06711.1 - 0.058 13.3 0.3 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 FNIP Repeat Pox_A14 PF05767.7 EDO06712.1 - 0.062 13.2 0.1 0.062 13.2 0.1 3.6 3 1 0 3 3 3 0 Poxvirus virion envelope protein A14 BCAS2 PF05700.6 EDO06713.1 - 6.5e-20 71.5 0.5 7.8e-20 71.2 0.4 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Pkinase PF00069.20 EDO06714.1 - 8.8e-63 211.8 0.0 1.4e-62 211.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO06714.1 - 2.5e-27 95.6 0.0 3.7e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_8 PF13833.1 EDO06714.1 - 2.7e-07 30.0 0.2 0.0013 18.3 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EDO06714.1 - 5.3e-07 28.4 0.0 0.0024 17.0 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EDO06714.1 - 1.6e-06 28.1 0.0 0.058 13.5 0.0 3.0 2 1 1 3 3 3 3 EF-hand domain pair Kinase-like PF14531.1 EDO06714.1 - 0.00053 19.0 0.0 0.00094 18.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like EF-hand_6 PF13405.1 EDO06714.1 - 0.0011 18.6 0.2 0.98 9.4 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EDO06714.1 - 0.0041 16.3 0.0 2.3 7.7 0.0 2.9 2 0 0 2 2 2 2 EF hand Kdo PF06293.9 EDO06714.1 - 0.014 14.5 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO06714.1 - 0.042 13.5 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3490 PF11995.3 EDO06714.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) EcKinase PF02958.15 EDO06714.1 - 0.075 12.1 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase PV-1 PF06637.6 EDO06714.1 - 0.17 10.4 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) ADIP PF11559.3 EDO06715.1 - 0.00085 19.2 4.6 0.00085 19.2 3.2 4.4 3 2 1 4 4 4 2 Afadin- and alpha -actinin-Binding Rootletin PF15035.1 EDO06715.1 - 0.0058 16.6 5.2 0.0058 16.6 3.6 4.1 2 1 0 3 3 3 1 Ciliary rootlet component, centrosome cohesion EF_assoc_1 PF08355.7 EDO06715.1 - 0.047 12.9 0.1 0.14 11.4 0.1 1.8 1 0 0 1 1 1 0 EF hand associated Reo_sigmaC PF04582.7 EDO06715.1 - 0.54 9.3 7.4 0.072 12.2 1.2 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 EDO06715.1 - 5.4 6.5 32.9 3.3 7.2 5.5 3.0 1 1 2 3 3 3 0 IncA protein TMF_DNA_bd PF12329.3 EDO06716.1 - 0.02 14.6 1.9 0.02 14.6 1.3 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 EDO06716.1 - 0.032 13.2 5.8 0.043 12.8 4.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Mycoplasma_p37 PF06646.6 EDO06716.1 - 0.054 12.5 0.4 0.12 11.4 0.2 1.5 1 1 0 1 1 1 0 High affinity transport system protein p37 DUF262 PF03235.9 EDO06716.1 - 0.11 12.4 3.8 0.14 12.1 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 MutS_IV PF05190.13 EDO06716.1 - 0.13 12.4 3.1 1.9 8.6 0.8 2.7 1 1 1 2 2 2 0 MutS family domain IV WGG PF10273.4 EDO06716.1 - 0.14 12.2 1.3 0.49 10.5 0.1 2.3 1 1 1 2 2 2 0 Pre-rRNA-processing protein TSR2 NPV_P10 PF05531.7 EDO06716.1 - 0.22 11.8 1.5 2.2 8.6 0.4 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein SPX PF03105.14 EDO06716.1 - 0.23 11.1 4.1 0.27 10.9 2.9 1.2 1 0 0 1 1 1 0 SPX domain V_ATPase_I PF01496.14 EDO06716.1 - 0.31 8.8 5.3 0.31 8.8 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 EDO06716.1 - 0.66 10.0 7.9 0.58 10.1 0.8 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 EDO06716.1 - 0.7 10.2 4.6 2.6 8.4 3.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4398 PF14346.1 EDO06716.1 - 3.6 7.7 9.5 0.6 10.1 4.1 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4398) DUF4140 PF13600.1 EDO06716.1 - 4.3 7.8 8.2 0.3 11.5 1.2 2.4 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.6 EDO06716.1 - 4.4 7.0 11.2 2.1e+02 1.6 7.8 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Cwf_Cwc_15 PF04889.7 EDO06716.1 - 6.9 6.2 9.6 11 5.6 6.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RabGAP-TBC PF00566.13 EDO06717.1 - 1.8e-48 164.8 1.4 2.8e-48 164.2 1.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ADK PF00406.17 EDO06718.1 - 7.1e-30 103.8 0.0 8.5e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 EDO06718.1 - 4.8e-13 49.1 0.0 5e-12 45.9 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EDO06718.1 - 3.8e-12 47.0 0.0 5.8e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO06718.1 - 9.6e-09 35.6 0.0 2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDO06718.1 - 6.9e-06 25.2 0.0 4.1e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 EDO06718.1 - 0.00057 20.0 0.0 0.011 15.8 0.0 2.4 1 1 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EDO06718.1 - 0.00058 19.8 0.0 0.0012 18.8 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDO06718.1 - 0.0011 19.0 0.0 0.0022 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EDO06718.1 - 0.0014 18.1 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.9 EDO06718.1 - 0.0021 17.8 0.0 0.0046 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EDO06718.1 - 0.0031 17.2 0.0 0.016 14.9 0.0 2.2 2 1 0 2 2 2 1 Part of AAA domain AAA_29 PF13555.1 EDO06718.1 - 0.0098 15.4 0.1 0.056 12.9 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_14 PF13173.1 EDO06718.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 EDO06718.1 - 0.02 13.6 0.0 0.048 12.4 0.0 1.6 1 0 0 1 1 1 0 ArgK protein MobB PF03205.9 EDO06718.1 - 0.023 14.3 0.0 0.1 12.2 0.0 2.0 1 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 EDO06718.1 - 0.037 13.2 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.13 EDO06718.1 - 0.038 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EDO06718.1 - 0.043 14.0 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EDO06718.1 - 0.045 12.6 0.0 0.065 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EDO06718.1 - 0.064 12.3 0.1 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 KaiC CPT PF07931.7 EDO06718.1 - 0.088 12.4 0.3 0.41 10.2 0.1 2.1 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.10 EDO06718.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 NTPase Mg_chelatase PF01078.16 EDO06718.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CoaE PF01121.15 EDO06718.1 - 0.12 11.7 0.0 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_10 PF12846.2 EDO06718.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain ATP_bind_1 PF03029.12 EDO06718.1 - 0.13 11.7 0.1 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SMC_N PF02463.14 EDO06718.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EDO06718.1 - 0.17 11.2 0.2 0.56 9.5 0.1 1.9 1 1 0 2 2 2 0 AAA domain UPF0203 PF05254.7 EDO06719.1 - 1.3e-12 47.3 6.6 1.6e-12 47.0 4.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.8 EDO06719.1 - 0.0022 17.8 5.5 0.98 9.4 0.1 3.0 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 EDO06719.1 - 0.027 14.2 7.4 0.18 11.6 5.2 2.3 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 EDO06719.1 - 0.18 11.8 7.9 0.13 12.2 0.5 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb COX17 PF05051.8 EDO06719.1 - 0.4 10.7 6.2 1.5 8.9 2.0 2.6 1 1 2 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.11 EDO06719.1 - 0.61 10.0 9.5 1.9 8.4 2.7 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein NDUF_B7 PF05676.8 EDO06719.1 - 2.1 7.8 5.8 1.4 8.4 0.3 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) KorB PF08535.5 EDO06720.1 - 0.0003 20.8 0.2 0.73 10.0 0.0 2.2 2 0 0 2 2 2 2 KorB domain Phage_min_cap2 PF06152.6 EDO06720.1 - 0.0086 15.0 0.5 0.0096 14.9 0.3 1.0 1 0 0 1 1 1 1 Phage minor capsid protein 2 DUF4413 PF14372.1 EDO06720.1 - 0.033 14.1 0.2 0.085 12.8 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4413) DUF1687 PF07955.6 EDO06720.1 - 0.076 12.9 0.3 0.16 11.9 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1687) TFX_C PF14601.1 EDO06720.1 - 0.12 12.1 0.2 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term VitK2_biosynth PF02621.9 EDO06720.1 - 0.12 11.5 0.2 0.25 10.4 0.1 1.5 1 1 1 2 2 2 0 Menaquinone biosynthesis BRE1 PF08647.6 EDO06720.1 - 0.15 12.0 2.1 0.32 10.9 1.5 1.6 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase ThiF PF00899.16 EDO06721.1 - 2.8e-43 147.0 10.5 3.6e-29 101.3 0.1 3.2 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 EDO06721.1 - 8.5e-35 119.6 0.0 2.2e-34 118.3 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EDO06721.1 - 1.9e-24 84.9 1.0 9.8e-24 82.7 0.2 2.6 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EDO06721.1 - 1e-21 75.9 0.8 2e-21 75.1 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Vac14_Fab1_bd PF12755.2 EDO06722.1 - 4.8e-25 87.7 0.1 4.8e-25 87.7 0.0 3.7 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.3 EDO06722.1 - 1e-22 80.1 1.7 2e-22 79.2 0.1 2.3 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.17 EDO06722.1 - 0.012 15.5 0.1 0.81 9.9 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat TatD_DNase PF01026.16 EDO06724.1 - 9.7e-48 162.5 0.0 1.2e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 EDO06724.1 - 0.01 15.4 0.0 0.13 11.7 0.0 2.1 1 1 0 2 2 2 0 Amidohydrolase Terpene_synth_C PF03936.11 EDO06724.1 - 0.04 13.1 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Kinesin PF00225.18 EDO06725.1 - 6.7e-83 278.1 0.1 9.5e-83 277.6 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Consortin_C PF15281.1 EDO06726.1 - 2.1 7.8 6.1 21 4.6 0.6 4.1 4 0 0 4 4 4 0 Consortin C-terminus DUF2207 PF09972.4 EDO06729.1 - 0.0016 17.1 0.3 0.002 16.7 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TspO_MBR PF03073.10 EDO06729.1 - 0.011 15.2 0.7 0.011 15.2 0.5 1.6 2 0 0 2 2 2 0 TspO/MBR family DUF3357 PF11837.3 EDO06729.1 - 0.022 14.5 0.2 0.52 10.1 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) RELT PF12606.3 EDO06729.1 - 0.023 13.8 2.7 0.023 13.8 1.9 1.8 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 DUF872 PF05915.7 EDO06729.1 - 0.11 12.3 0.1 2.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3624 PF12292.3 EDO06730.1 - 0.096 13.1 0.5 0.096 13.1 0.4 4.0 3 2 0 3 3 3 0 Protein of unknown function (DUF3624) VESA1_N PF12785.2 EDO06731.1 - 5.6e-202 671.7 52.2 1.2e-193 644.2 14.9 4.1 3 1 1 4 4 4 3 Variant erythrocyte surface antigen-1 Enolase_C PF00113.17 EDO06731.1 - 0.028 13.3 0.7 0.046 12.6 0.5 1.2 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain Rho_Binding PF08912.6 EDO06731.1 - 0.075 13.3 0.8 6.1 7.2 0.0 2.8 2 1 1 3 3 3 0 Rho Binding DUF937 PF06078.6 EDO06731.1 - 6.3 7.0 8.8 40 4.4 6.0 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF937) VESA1_N PF12785.2 EDO06733.1 - 8.2e-13 48.1 2.8 9.7e-13 47.8 1.9 1.1 1 0 0 1 1 1 1 Variant erythrocyte surface antigen-1 zf-piccolo PF05715.8 EDO06733.1 - 2.8 8.0 8.2 4.4 7.3 5.6 1.4 1 1 0 1 1 1 0 Piccolo Zn-finger AA_permease PF00324.16 EDO06735.1 - 0.0026 16.1 0.7 0.0036 15.7 0.5 1.2 1 0 0 1 1 1 1 Amino acid permease Cyto_ox_2 PF02322.10 EDO06735.1 - 0.0033 16.6 0.5 0.0036 16.5 0.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase subunit II Serpentine_r_xa PF03383.10 EDO06735.1 - 0.0048 16.6 0.1 0.0067 16.1 0.1 1.1 1 0 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa Baculo_11_kDa PF06143.6 EDO06735.1 - 0.01 15.1 1.4 0.32 10.4 0.2 2.3 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF2207 PF09972.4 EDO06735.1 - 0.011 14.4 0.4 0.012 14.1 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SdpI PF13630.1 EDO06735.1 - 0.019 14.6 2.2 0.044 13.4 1.5 1.7 1 0 0 1 1 1 0 SdpI/YhfL protein family ABC2_membrane_5 PF13346.1 EDO06735.1 - 0.02 14.2 0.7 0.026 13.8 0.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein YjgP_YjgQ PF03739.9 EDO06735.1 - 0.023 13.4 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family CopD PF05425.8 EDO06735.1 - 0.026 14.7 1.5 0.026 14.7 1.0 1.5 2 0 0 2 2 2 0 Copper resistance protein D DUF4079 PF13301.1 EDO06735.1 - 0.027 14.4 0.8 0.033 14.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF1385 PF07136.6 EDO06735.1 - 0.04 12.9 0.4 0.067 12.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1385) DUF3671 PF12420.3 EDO06735.1 - 0.049 13.5 0.9 0.11 12.4 0.1 1.9 2 1 1 3 3 3 0 Protein of unknown function DUF2142 PF09913.4 EDO06735.1 - 0.072 11.7 3.6 0.11 11.1 2.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF805 PF05656.9 EDO06735.1 - 0.096 12.5 2.6 0.17 11.6 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) TMEM237 PF15383.1 EDO06735.1 - 0.11 11.6 0.4 3.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 237 DUF4231 PF14015.1 EDO06735.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF2839 PF10999.3 EDO06735.1 - 0.16 12.0 4.2 8.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) DUF4173 PF13777.1 EDO06735.1 - 0.29 10.4 3.0 0.4 9.9 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) Fumarate_red_D PF02313.12 EDO06735.1 - 0.6 10.0 0.0 0.6 10.0 0.0 2.7 2 1 1 3 3 2 0 Fumarate reductase subunit D XK-related PF09815.4 EDO06735.1 - 1.5 7.7 4.7 2 7.3 3.3 1.1 1 0 0 1 1 1 0 XK-related protein DUF998 PF06197.8 EDO06735.1 - 1.7 7.9 10.4 0.44 9.8 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Sdh_cyt PF01127.17 EDO06735.1 - 2.6 7.9 5.9 11 5.8 3.3 1.9 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SHP PF03579.8 EDO06735.1 - 3 7.2 5.7 1.5 8.2 0.1 2.2 2 0 0 2 2 2 0 Small hydrophobic protein ACDC PF14733.1 EDO06736.1 - 0.00092 19.2 0.1 0.0023 18.0 0.1 1.7 1 0 0 1 1 1 1 AP2-coincident C-terminal DUF1411 PF07199.6 EDO06736.1 - 0.036 13.5 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) Actin PF00022.14 EDO06737.1 - 1.2e-45 155.5 0.0 1.5e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EDO06737.1 - 0.01 14.4 0.1 0.014 13.9 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein MtN3_slv PF03083.11 EDO06739.1 - 2.1e-25 88.4 16.9 3.9e-15 55.4 1.9 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange LAB_N PF07578.6 EDO06739.1 - 0.0031 17.3 0.5 0.0031 17.3 0.3 2.3 2 1 0 2 2 2 1 Lipid A Biosynthesis N-terminal domain ATP_bind_1 PF03029.12 EDO06740.1 - 1.3e-61 208.1 0.0 1.6e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EDO06740.1 - 0.0014 19.4 0.0 0.0042 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 EDO06740.1 - 0.0068 15.8 0.0 0.0079 15.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EDO06740.1 - 0.0088 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_19 PF13245.1 EDO06740.1 - 0.014 15.1 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EDO06740.1 - 0.026 14.3 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EDO06740.1 - 0.036 13.6 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EDO06740.1 - 0.037 14.2 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 EDO06740.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EDO06740.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDO06740.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CLP_protease PF00574.18 EDO06741.1 - 1.7e-58 197.3 0.1 2e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Clp protease PfkB PF00294.19 EDO06742.1 - 5.9e-38 130.7 0.0 7.1e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MtN3_slv PF03083.11 EDO06743.1 - 2.1e-25 88.4 16.9 3.9e-15 55.4 1.9 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange LAB_N PF07578.6 EDO06743.1 - 0.0031 17.3 0.5 0.0031 17.3 0.3 2.3 2 1 0 2 2 2 1 Lipid A Biosynthesis N-terminal domain ATP_bind_1 PF03029.12 EDO06745.1 - 1.3e-61 208.1 0.0 1.6e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EDO06745.1 - 0.0014 19.4 0.0 0.0042 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 EDO06745.1 - 0.0068 15.8 0.0 0.0079 15.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EDO06745.1 - 0.0088 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_19 PF13245.1 EDO06745.1 - 0.014 15.1 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EDO06745.1 - 0.026 14.3 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EDO06745.1 - 0.036 13.6 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EDO06745.1 - 0.037 14.2 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 EDO06745.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EDO06745.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDO06745.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CLP_protease PF00574.18 EDO06746.1 - 3.1e-58 196.4 0.1 4e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Clp protease PfkB PF00294.19 EDO06747.1 - 1.3e-44 152.5 0.0 1.6e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EDO06747.1 - 0.0087 15.2 0.0 0.021 14.0 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase ThiF PF00899.16 EDO06748.1 - 2.6e-37 127.6 0.1 4.4e-37 126.9 0.1 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EDO06748.1 - 5.7e-18 64.2 1.3 1.2e-17 63.2 0.9 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EDO06748.1 - 2e-05 24.9 0.0 6.2e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EDO06748.1 - 0.0011 19.0 0.2 0.034 14.2 0.1 2.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 EDO06748.1 - 0.023 14.6 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DnaJ PF00226.26 EDO06749.1 - 0.0043 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DUF2205 PF10224.4 EDO06749.1 - 0.11 12.1 0.5 0.4 10.2 0.3 1.9 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Rad60-SLD PF11976.3 EDO06751.1 - 2e-23 81.8 0.0 2.3e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EDO06751.1 - 1.2e-08 34.1 0.0 1.6e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family UBX PF00789.15 EDO06751.1 - 0.047 13.7 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 UBX domain DUF4115 PF13464.1 EDO06751.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4115) HEAT PF02985.17 EDO06752.1 - 0.0029 17.5 0.6 5.7 7.2 0.1 3.8 4 0 0 4 4 4 2 HEAT repeat Laminin_II PF06009.7 EDO06753.1 - 0.00044 20.0 2.7 0.00073 19.3 1.8 1.3 1 0 0 1 1 1 1 Laminin Domain II Seryl_tRNA_N PF02403.17 EDO06753.1 - 0.0021 18.0 5.0 0.0033 17.4 3.4 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain ALIX_LYPXL_bnd PF13949.1 EDO06753.1 - 0.0089 15.0 2.8 0.014 14.3 1.9 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Occludin_ELL PF07303.8 EDO06753.1 - 0.036 14.8 1.5 0.068 13.9 1.1 1.5 1 0 0 1 1 1 0 Occludin homology domain TMF_TATA_bd PF12325.3 EDO06753.1 - 0.13 11.9 5.6 0.2 11.4 3.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 EDO06753.1 - 0.18 12.1 2.1 0.37 11.1 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) T2SM PF04612.7 EDO06753.1 - 0.35 10.6 3.1 0.94 9.2 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF4140 PF13600.1 EDO06753.1 - 0.64 10.5 6.8 6.8 7.1 0.3 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 EDO06753.1 - 0.72 9.4 4.0 1.1 8.8 2.8 1.2 1 0 0 1 1 1 0 IncA protein RAP PF08373.5 EDO06754.1 - 4.5e-15 55.1 0.4 1e-14 54.0 0.3 1.7 1 0 0 1 1 1 1 RAP domain DUF559 PF04480.7 EDO06754.1 - 0.0023 17.5 0.1 0.0075 15.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF559) Myb_DNA-bind_6 PF13921.1 EDO06755.1 - 3e-15 56.0 0.6 1.9e-13 50.2 0.2 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDO06755.1 - 0.1 12.6 1.1 6.4 6.9 0.0 3.0 3 0 0 3 3 3 0 Myb-like DNA-binding domain IRF-3 PF10401.4 EDO06757.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Interferon-regulatory factor 3 RRM_1 PF00076.17 EDO06758.1 - 1.1e-22 79.3 0.3 3.3e-22 77.9 0.2 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06758.1 - 2.3e-18 65.9 0.1 8.6e-18 64.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06758.1 - 6.9e-14 51.4 0.7 1.6e-13 50.2 0.5 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO06758.1 - 0.074 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EDO06758.1 - 0.097 12.5 0.9 0.31 10.9 0.0 2.1 2 1 0 2 2 2 0 RNA binding motif SseB_C PF14581.1 EDO06758.1 - 0.12 12.2 0.0 0.37 10.6 0.0 1.9 2 1 0 2 2 2 0 SseB protein C-terminal domain AAR2 PF05282.6 EDO06760.1 - 4.7e-100 335.0 0.0 6e-100 334.6 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein Bromodomain PF00439.20 EDO06761.1 - 6.2e-09 35.6 0.1 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain WD40 PF00400.27 EDO06761.1 - 4e-07 29.6 10.0 0.007 16.2 0.4 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat zf-HC5HC2H PF13771.1 EDO06761.1 - 1.8e-05 24.7 1.6 8.3e-05 22.6 1.1 2.2 1 0 0 1 1 1 1 PHD-like zinc-binding domain WD40 PF00400.27 EDO06762.1 - 3e-19 68.1 9.4 1.8e-05 24.4 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat UTP15_C PF09384.5 EDO06762.1 - 2.1e-15 56.7 0.1 3.4e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal Dexa_ind PF15198.1 EDO06763.1 - 0.015 15.1 0.1 0.058 13.3 0.0 1.9 2 0 0 2 2 2 0 Dexamethasone-induced Cyclase_polyket PF04673.7 EDO06764.1 - 0.012 15.5 0.0 0.36 10.9 0.1 2.4 2 0 0 2 2 2 0 Polyketide synthesis cyclase Ribosomal_S11 PF00411.14 EDO06765.1 - 2.7e-06 27.5 0.2 4.1e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L18p PF00861.17 EDO06765.1 - 0.00014 22.0 0.1 0.00025 21.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L18p/L5e family EF-hand_7 PF13499.1 EDO06765.1 - 0.049 13.7 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair NifU_N PF01592.11 EDO06766.1 - 1.1e-45 154.7 0.2 1.3e-45 154.4 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain IL7 PF01415.11 EDO06766.1 - 0.088 12.4 0.5 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 Interleukin 7/9 family 6PGD PF00393.14 EDO06767.1 - 6e-82 275.1 0.6 7.5e-82 274.8 0.4 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EDO06767.1 - 2e-33 115.5 0.0 3.7e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EDO06767.1 - 0.002 17.8 0.0 0.0041 16.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EDO06767.1 - 0.023 14.0 0.0 0.062 12.6 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HC2 PF07382.6 EDO06769.1 - 0.00058 19.7 34.7 0.00058 19.7 24.0 2.4 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 Alg14 PF08660.6 EDO06770.1 - 1.5e-42 145.4 0.0 1.9e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Gsf2 PF11055.3 EDO06770.1 - 0.042 12.3 0.1 0.058 11.9 0.1 1.2 1 0 0 1 1 1 0 Glucose signalling factor 2 MMR_HSR1 PF01926.18 EDO06771.1 - 2.7e-17 62.7 0.0 5.1e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO06771.1 - 6.2e-09 35.3 0.0 0.00019 20.7 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 EDO06771.1 - 1.1e-06 28.1 0.0 0.0021 17.5 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EDO06771.1 - 3e-05 23.9 0.0 0.0079 16.0 0.0 2.3 2 0 0 2 2 2 2 Dynamin family DUF258 PF03193.11 EDO06771.1 - 7e-05 22.0 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EDO06771.1 - 0.00053 19.0 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 Septin Miro PF08477.8 EDO06771.1 - 0.004 17.6 0.0 0.0099 16.3 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EDO06771.1 - 0.012 14.7 0.0 0.036 13.1 0.0 1.8 2 0 0 2 2 2 0 AIG1 family MobB PF03205.9 EDO06771.1 - 0.022 14.4 0.0 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 EDO06771.1 - 0.026 13.3 0.0 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 EDO06771.1 - 0.093 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.1 EDO06771.1 - 0.093 11.7 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain zf-RING_4 PF14570.1 EDO06772.1 - 1.1e-18 66.5 12.1 2.1e-18 65.6 8.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 EDO06772.1 - 3.4e-07 30.0 0.0 6.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EDO06772.1 - 4.8e-06 26.1 6.9 9.4e-06 25.2 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 EDO06772.1 - 9.8e-05 21.9 0.0 0.00024 20.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO06772.1 - 0.004 16.8 0.1 0.0096 15.6 0.1 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-UDP PF14569.1 EDO06772.1 - 0.0093 15.6 2.6 0.023 14.4 1.8 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-C3HC4 PF00097.20 EDO06772.1 - 0.23 11.1 10.7 0.49 10.1 7.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDO06772.1 - 8 6.4 11.0 35 4.3 7.8 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ZPR1 PF03367.8 EDO06773.1 - 1.9e-70 235.1 0.0 2.2e-35 121.2 0.0 3.0 2 1 0 2 2 2 2 ZPR1 zinc-finger domain zinc_ribbon_4 PF13717.1 EDO06773.1 - 0.0026 17.4 3.9 5.4 6.7 0.2 3.5 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EDO06773.1 - 0.0035 16.9 3.8 7.1 6.3 0.2 3.6 3 0 0 3 3 3 1 zinc-ribbon domain zf-H2C2_2 PF13465.1 EDO06773.1 - 0.0037 17.4 2.1 7.7 7.0 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain Zn-ribbon_8 PF09723.5 EDO06773.1 - 0.025 14.5 5.1 13 5.7 0.1 4.0 4 0 0 4 4 4 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EDO06773.1 - 0.037 13.2 15.2 2.1 7.6 0.2 4.0 4 0 0 4 4 4 0 zinc-ribbon domain CorC_HlyC PF03471.12 EDO06773.1 - 0.12 12.1 0.5 3.3 7.5 0.0 2.9 3 0 0 3 3 3 0 Transporter associated domain zf-AN1 PF01428.11 EDO06773.1 - 0.16 11.8 4.6 20 5.1 0.0 3.5 3 0 0 3 3 3 0 AN1-like Zinc finger zf-DNL PF05180.7 EDO06773.1 - 0.2 11.3 1.5 3.5 7.4 0.0 2.9 3 0 0 3 3 3 0 DNL zinc finger OrfB_Zn_ribbon PF07282.6 EDO06773.1 - 0.41 10.3 6.2 11 5.8 0.0 3.3 2 1 1 3 3 3 0 Putative transposase DNA-binding domain DZR PF12773.2 EDO06773.1 - 0.53 10.1 10.4 1.4 8.7 0.1 3.3 2 2 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EDO06773.1 - 1.9 8.0 16.8 15 5.2 0.2 4.3 4 0 0 4 4 4 0 zinc-ribbon domain UPF0547 PF10571.4 EDO06773.1 - 2.2 8.0 10.1 3.4 7.4 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-Mss51 PF13824.1 EDO06773.1 - 2.8 7.8 10.3 18 5.3 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Sgf11 PF08209.6 EDO06773.1 - 3.7 6.9 5.6 14 5.0 0.1 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-ISL3 PF14690.1 EDO06773.1 - 4.7 7.3 10.0 17 5.5 0.8 3.5 4 0 0 4 4 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.2 EDO06773.1 - 7.4 6.4 11.2 33 4.3 0.0 3.3 3 1 1 4 4 3 0 Transposase zinc-ribbon domain DUF2428 PF10350.4 EDO06774.1 - 4.9e-18 65.0 0.0 1.2e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) RRM_1 PF00076.17 EDO06776.1 - 1.5e-18 66.1 0.3 2.2e-18 65.6 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06776.1 - 9.6e-13 47.7 0.0 1.3e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06776.1 - 1.8e-12 47.0 0.1 2.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO06776.1 - 0.011 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif TB2_DP1_HVA22 PF03134.14 EDO06778.1 - 5.9e-12 45.1 4.7 1.3e-11 44.0 3.2 1.5 1 1 0 1 1 1 1 TB2/DP1, HVA22 family KH_5 PF13184.1 EDO06779.1 - 0.048 13.4 0.3 1.4 8.8 0.1 2.6 3 0 0 3 3 3 0 NusA-like KH domain Ribosomal_L12 PF00542.14 EDO06779.1 - 0.12 12.3 0.0 16 5.6 0.0 3.0 3 0 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain GTP_EFTU PF00009.22 EDO06780.1 - 4.7e-39 133.7 0.0 7.3e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EDO06780.1 - 2.2e-36 123.7 0.0 6.2e-36 122.3 0.0 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EDO06780.1 - 1.3e-10 41.2 3.6 1.6e-10 40.9 0.5 2.5 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO06780.1 - 0.0039 17.1 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF824 PF05688.6 EDO06780.1 - 0.049 13.2 1.4 7.5 6.2 0.0 3.0 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) TRAPP PF04051.11 EDO06783.1 - 1.6e-29 102.3 0.1 1.9e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Acetyltransf_CG PF14542.1 EDO06783.1 - 0.11 12.4 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase NOB1_Zn_bind PF08772.6 EDO06784.1 - 1.3e-24 85.7 0.1 3.1e-24 84.5 0.1 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DUF2321 PF10083.4 EDO06784.1 - 0.0032 16.9 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2321) Nudix_N_2 PF14803.1 EDO06784.1 - 0.26 11.0 0.1 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Nudix N-terminal TPM PF04536.9 EDO06785.1 - 2.1e-05 24.3 0.0 2.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase UPF0054 PF02130.12 EDO06786.1 - 1.2e-20 73.3 0.8 1.6e-20 72.8 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 DUF3591 PF12157.3 EDO06787.1 - 7e-34 117.0 0.0 1.3e-29 102.9 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3591) Bromodomain PF00439.20 EDO06787.1 - 6.2e-11 42.0 1.9 1.5e-10 40.8 0.1 2.4 2 0 0 2 2 2 1 Bromodomain zf-CCHC_6 PF15288.1 EDO06787.1 - 0.00086 18.9 1.0 0.0031 17.1 0.7 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EDO06787.1 - 0.02 14.8 0.3 0.046 13.6 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle EMP24_GP25L PF01105.19 EDO06788.1 - 1.4e-24 86.8 0.7 2.7e-24 85.8 0.0 1.8 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD Tubulin PF00091.20 EDO06790.1 - 7.8e-62 208.9 0.0 1.1e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDO06790.1 - 2.1e-46 157.0 0.1 4.7e-46 155.9 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Glutaredoxin PF00462.19 EDO06793.1 - 4.4e-16 58.6 0.0 8.6e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 EDO06793.1 - 0.0018 18.0 0.0 0.0028 17.4 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 EDO06793.1 - 0.0025 18.0 0.2 0.0033 17.6 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EDO06793.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin DUF836 PF05768.9 EDO06793.1 - 0.039 14.2 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.1 EDO06793.1 - 0.078 12.9 0.1 6.7 6.6 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Trypsin PF00089.21 EDO06794.1 - 7.1e-19 68.2 0.1 1.2e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EDO06794.1 - 1.1e-11 44.7 0.3 2e-11 43.9 0.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EDO06794.1 - 1e-06 28.5 0.1 1.7e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 PDZ domain Ribosomal_L10 PF00466.15 EDO06795.1 - 4.2e-07 29.8 0.0 1.4e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L10 UCH PF00443.24 EDO06796.1 - 3.2e-48 164.1 0.3 1.1e-47 162.4 0.7 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO06796.1 - 3.1e-15 56.3 0.0 7.6e-15 55.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EDO06796.1 - 2.3e-12 46.8 1.4 9.5e-12 44.8 0.0 2.5 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EDO06796.1 - 1e-09 37.9 3.4 0.00013 21.6 0.3 2.7 2 0 0 2 2 2 2 UBA/TS-N domain Adaptin_N PF01602.15 EDO06796.1 - 0.026 12.8 0.1 0.042 12.1 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region ubiquitin PF00240.18 EDO06797.1 - 9.7e-05 21.6 0.0 0.0002 20.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EDO06797.1 - 0.083 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain RRM_1 PF00076.17 EDO06798.1 - 1.2e-16 60.0 0.1 4.7e-16 58.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06798.1 - 3.6e-14 52.4 0.0 8.6e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06798.1 - 6.9e-09 35.4 0.0 1.6e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.3 EDO06798.1 - 1.3e-08 34.8 0.3 2.1e-08 34.1 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Nup35_RRM_2 PF14605.1 EDO06798.1 - 0.12 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Folate_rec PF03024.9 EDO06799.1 - 0.082 12.5 0.3 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 Folate receptor family CDtoxinA PF03498.9 EDO06799.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family Pox_A_type_inc PF04508.7 EDO06799.1 - 0.19 11.5 1.8 0.42 10.5 1.3 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat ELM2 PF01448.19 EDO06800.1 - 1.2e-05 25.8 0.4 1.7e-05 25.3 0.3 1.7 1 1 0 1 1 1 1 ELM2 domain DnaJ PF00226.26 EDO06802.1 - 1e-18 66.7 0.6 1.3e-18 66.4 0.4 1.2 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 EDO06803.1 - 1e-05 25.0 0.0 0.0013 18.3 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06803.1 - 0.00024 21.0 0.0 0.00079 19.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06803.1 - 0.0017 18.1 0.2 0.012 15.4 0.1 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EXOSC1 PF10447.4 EDO06804.1 - 4.5e-20 71.3 0.1 6.6e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 EDO06804.1 - 0.0096 15.9 0.0 0.052 13.6 0.0 2.1 1 1 0 1 1 1 1 S1 RNA binding domain Leptin PF02024.10 EDO06804.1 - 0.061 12.9 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Leptin TRAPPC9-Trs120 PF08626.6 EDO06805.1 - 0.0091 13.3 0.2 0.019 12.3 0.0 1.5 2 0 0 2 2 2 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Borealin PF10512.4 EDO06806.1 - 0.047 13.6 27.8 3.2 7.7 0.3 9.3 4 3 4 10 10 10 0 Cell division cycle-associated protein 8 Rieske_2 PF13806.1 EDO06807.1 - 7.9e-05 22.3 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 EDO06807.1 - 9.3e-05 21.9 0.2 0.00026 20.4 0.1 1.7 1 1 1 2 2 2 1 Rieske [2Fe-2S] domain Pkinase PF00069.20 EDO06808.1 - 2.9e-48 164.2 0.0 5.2e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO06808.1 - 2.3e-21 76.0 0.0 7.2e-21 74.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EDO06808.1 - 1.9e-05 24.5 0.0 4.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDO06808.1 - 0.0053 16.1 0.1 0.4 10.0 0.0 2.5 2 0 0 2 2 2 1 RIO1 family Pox_ser-thr_kin PF05445.6 EDO06808.1 - 0.026 13.3 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase NAD_Gly3P_dh_N PF01210.18 EDO06809.1 - 7.4e-45 152.4 0.2 2.7e-44 150.6 0.1 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EDO06809.1 - 4.3e-43 146.5 0.2 6.9e-43 145.9 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 2-Hacid_dh_C PF02826.14 EDO06809.1 - 1.2e-05 24.5 0.1 0.048 12.8 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EDO06809.1 - 0.0045 16.3 1.3 3.4 7.0 0.0 3.9 4 0 0 4 4 4 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EDO06809.1 - 0.0072 16.7 0.0 0.19 12.1 0.0 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 EDO06809.1 - 0.057 13.2 0.4 0.18 11.5 0.0 2.0 2 1 0 2 2 2 0 ThiF family U-box PF04564.10 EDO06810.1 - 3e-25 87.9 0.2 7.5e-25 86.6 0.0 1.8 2 0 0 2 2 2 1 U-box domain TPR_11 PF13414.1 EDO06810.1 - 5e-23 80.5 2.3 3.9e-18 64.8 0.9 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDO06810.1 - 9e-17 59.5 3.4 6.7e-05 22.5 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EDO06810.1 - 5.1e-16 57.5 4.6 9.8e-06 24.9 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDO06810.1 - 3.1e-12 45.6 0.7 1.7e-06 27.7 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EDO06810.1 - 5.9e-12 45.5 0.7 1.4e-11 44.3 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EDO06810.1 - 6.3e-10 39.4 0.1 1.4e-05 25.6 0.0 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO06810.1 - 6.1e-07 29.2 1.1 0.00029 20.7 0.1 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDO06810.1 - 1e-06 28.0 6.1 0.028 14.1 0.2 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDO06810.1 - 4.9e-06 26.7 0.0 0.31 11.7 0.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDO06810.1 - 5.8e-06 26.5 0.6 0.037 14.3 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat NARP1 PF12569.3 EDO06810.1 - 0.00031 19.6 0.0 0.00046 19.0 0.0 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 EDO06810.1 - 0.00033 19.8 0.3 0.00051 19.1 0.2 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDO06810.1 - 0.00059 19.6 0.0 0.014 15.2 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO06810.1 - 0.0025 18.1 2.4 4.9 7.8 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat AF0941-like PF14591.1 EDO06810.1 - 0.062 13.3 0.7 0.4 10.7 0.4 2.1 1 1 1 2 2 2 0 AF0941-like TPR_7 PF13176.1 EDO06810.1 - 0.092 12.5 0.3 1.2e+02 2.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat GTP1_OBG PF01018.17 EDO06811.1 - 3.4e-31 108.0 2.3 4e-31 107.7 1.1 1.4 2 0 0 2 2 2 1 GTP1/OBG MMR_HSR1 PF01926.18 EDO06812.1 - 4.2e-18 65.3 0.3 2.6e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF1967 PF09269.6 EDO06812.1 - 1.9e-16 59.5 0.1 3.4e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) Dynamin_N PF00350.18 EDO06812.1 - 5.1e-06 26.4 0.3 0.00015 21.6 0.2 2.3 1 1 0 1 1 1 1 Dynamin family GTP1_OBG PF01018.17 EDO06812.1 - 6.5e-06 25.8 0.1 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.13 EDO06812.1 - 7e-06 25.4 0.7 0.0016 17.7 0.0 2.5 2 1 0 2 2 2 2 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EDO06812.1 - 0.00016 20.9 0.0 0.0023 17.1 0.1 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region cobW PF02492.14 EDO06812.1 - 0.00032 20.2 0.1 0.0052 16.2 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 EDO06812.1 - 0.0042 16.5 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.16 EDO06812.1 - 0.0078 15.4 0.2 0.029 13.6 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_21 PF13304.1 EDO06812.1 - 0.03 14.2 0.3 0.03 14.2 0.2 2.4 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EDO06812.1 - 0.033 13.6 0.0 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation EF-hand_7 PF13499.1 EDO06813.1 - 1.6e-07 31.3 0.0 2.9e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EDO06813.1 - 1e-06 27.5 0.1 0.00012 21.1 0.0 3.4 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 EDO06813.1 - 4.9e-06 25.9 0.0 0.11 12.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EDO06813.1 - 1.8e-05 24.2 0.0 5.6e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EDO06813.1 - 0.0059 15.9 0.4 0.03 13.6 0.0 2.4 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 EDO06813.1 - 0.021 14.6 0.0 0.77 9.7 0.0 2.4 3 0 0 3 3 3 0 EF-hand domain IncA PF04156.9 EDO06814.1 - 0.00024 20.7 38.3 0.11 12.0 2.2 5.6 6 0 0 6 6 6 4 IncA protein Tup_N PF08581.5 EDO06814.1 - 0.0017 18.5 3.0 0.0017 18.5 2.1 3.7 6 0 0 6 6 6 1 Tup N-terminal DUF4047 PF13256.1 EDO06814.1 - 0.14 12.1 5.3 0.13 12.2 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) Ribosomal_L10 PF00466.15 EDO06815.1 - 2.3e-20 72.3 0.0 4.9e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EDO06815.1 - 1.1e-16 61.0 1.7 1.1e-16 61.0 1.2 2.1 3 0 0 3 3 3 1 60s Acidic ribosomal protein Ribosomal_L38e PF01781.13 EDO06816.1 - 9.3e-28 95.7 0.3 1e-27 95.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Lactamase_B PF00753.22 EDO06817.1 - 3.4e-18 66.0 0.2 4.8e-18 65.5 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EDO06817.1 - 1.8e-05 24.3 0.0 2.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2981 PF11200.3 EDO06818.1 - 5.5e-35 120.9 2.4 5.6e-28 97.9 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2981) Tetraspannin PF00335.15 EDO06818.1 - 0.57 9.4 9.1 1.2 8.3 6.3 1.4 1 0 0 1 1 1 0 Tetraspanin family AAA PF00004.24 EDO06819.1 - 4.5e-42 143.3 0.0 8.9e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO06819.1 - 1.6e-07 31.0 0.1 1e-06 28.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO06819.1 - 3.7e-06 27.0 0.1 0.001 19.1 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EDO06819.1 - 2.2e-05 23.6 0.0 6.6e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EDO06819.1 - 3.3e-05 23.8 0.0 0.00012 22.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EDO06819.1 - 0.00031 20.6 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO06819.1 - 0.00034 20.7 0.4 0.015 15.4 0.3 2.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EDO06819.1 - 0.0011 18.1 0.2 0.024 13.7 0.1 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EDO06819.1 - 0.0015 18.1 0.3 0.0036 17.0 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EDO06819.1 - 0.0032 17.3 0.0 0.0068 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EDO06819.1 - 0.0044 16.2 0.1 0.01 15.0 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein TIP49 PF06068.8 EDO06819.1 - 0.0059 15.3 1.2 0.068 11.8 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 EDO06819.1 - 0.006 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EDO06819.1 - 0.013 14.6 0.1 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.21 EDO06819.1 - 0.02 14.3 0.1 0.13 11.7 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 EDO06819.1 - 0.023 15.5 0.3 0.071 13.9 0.0 2.1 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.1 EDO06819.1 - 0.029 13.9 0.2 0.13 11.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EDO06819.1 - 0.043 12.9 0.1 0.21 10.6 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_3 PF07726.6 EDO06819.1 - 0.071 12.7 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EDO06819.1 - 0.075 12.6 0.3 1.2 8.7 0.0 2.3 1 1 1 2 2 2 0 NACHT domain DUF3510 PF12022.3 EDO06820.1 - 1.9e-29 102.2 3.5 1.9e-29 102.2 2.4 4.1 4 2 1 6 6 6 1 Domain of unknown function (DUF3510) Ufm1 PF03671.9 EDO06821.1 - 8.3e-25 86.3 0.1 9.6e-25 86.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein RA PF00788.18 EDO06821.1 - 0.026 14.9 0.0 0.031 14.7 0.0 1.2 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain SMC_N PF02463.14 EDO06822.1 - 9.2e-56 188.5 0.0 2.8e-55 186.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDO06822.1 - 9.6e-19 67.5 0.1 1e-17 64.1 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EDO06822.1 - 1.2e-14 54.9 10.2 2.5e-08 34.2 0.2 3.5 2 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EDO06822.1 - 1e-12 48.8 14.5 1e-12 48.8 10.1 5.4 2 2 1 3 3 2 1 AAA domain AAA_29 PF13555.1 EDO06822.1 - 1.9e-08 33.6 0.0 4.3e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.6 EDO06822.1 - 0.0025 17.6 11.1 0.0025 17.6 7.7 6.4 3 2 2 6 6 6 1 Autophagy protein 16 (ATG16) SbcCD_C PF13558.1 EDO06822.1 - 0.0036 17.1 0.1 0.0093 15.8 0.1 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF4200 PF13863.1 EDO06822.1 - 0.0046 16.9 7.5 0.0046 16.9 5.2 7.7 7 1 2 9 9 9 2 Domain of unknown function (DUF4200) AAA_22 PF13401.1 EDO06822.1 - 0.0064 16.6 4.4 1 9.5 0.0 4.0 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.22 EDO06822.1 - 0.036 14.3 0.0 0.036 14.3 0.0 4.8 4 1 0 4 4 3 0 ABC transporter DUF869 PF05911.6 EDO06822.1 - 0.19 9.9 72.6 0.018 13.2 8.7 4.4 2 2 1 4 4 4 0 Plant protein of unknown function (DUF869) GAS PF13851.1 EDO06822.1 - 0.43 9.7 76.4 0.5 9.5 0.0 6.9 4 1 3 7 7 7 0 Growth-arrest specific micro-tubule binding AAA_15 PF13175.1 EDO06822.1 - 0.96 8.4 24.7 0.72 8.8 10.4 3.7 3 1 0 3 3 3 0 AAA ATPase domain RRM_1 PF00076.17 EDO06823.1 - 4.1e-21 74.3 0.0 2.9e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06823.1 - 2.9e-17 62.4 0.0 4.1e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06823.1 - 1.9e-11 43.6 0.0 4.7e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT_2 PF13646.1 EDO06826.1 - 1.9e-18 66.4 0.2 3.7e-06 27.1 0.0 7.0 5 3 2 7 7 7 5 HEAT repeats HEAT PF02985.17 EDO06826.1 - 5e-16 57.2 8.3 0.034 14.2 0.0 10.1 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 EDO06826.1 - 1.2e-11 44.7 0.0 0.0031 17.9 0.0 8.1 8 1 1 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EDO06826.1 - 1.7e-09 37.9 9.5 0.0032 17.8 0.0 6.6 5 3 2 7 7 7 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EDO06826.1 - 0.0013 18.4 0.1 28 4.7 0.0 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF3730 PF12530.3 EDO06826.1 - 0.0014 18.5 2.4 0.0087 16.0 0.2 3.2 2 2 1 3 3 3 1 Protein of unknown function (DUF3730) Ku_PK_bind PF08785.6 EDO06826.1 - 0.033 14.0 1.6 9.9 6.0 0.0 4.1 4 0 0 4 4 4 0 Ku C terminal domain like MIF4G PF02854.14 EDO06826.1 - 4.6 6.5 12.9 35 3.7 0.1 5.4 4 3 0 4 4 4 0 MIF4G domain SET PF00856.23 EDO06829.1 - 1.2e-17 64.6 0.1 5.3e-17 62.6 0.0 2.2 1 1 0 1 1 1 1 SET domain Ribosomal_S6 PF01250.12 EDO06829.1 - 0.079 12.8 0.1 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S6 TFIID_30kDa PF03540.8 EDO06830.1 - 0.08 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit TGS PF02824.16 EDO06831.1 - 2e-21 75.5 0.1 3.7e-21 74.7 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EDO06831.1 - 1.6e-20 73.1 0.0 4e-20 71.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO06831.1 - 4.6e-13 48.7 0.1 1.3e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EDO06831.1 - 1.3e-06 28.3 0.1 0.0098 15.7 0.0 2.5 1 1 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EDO06831.1 - 0.00078 18.9 0.6 2.1 7.7 0.0 4.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EDO06831.1 - 0.0012 17.6 0.2 0.003 16.3 0.1 1.7 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EDO06831.1 - 0.003 18.0 0.0 0.0069 16.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EDO06831.1 - 0.0098 15.0 0.1 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 EDO06831.1 - 0.043 13.0 0.0 0.079 12.1 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EDO06831.1 - 0.092 13.0 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EDO06831.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EDO06832.1 - 1.2e-58 197.6 0.0 2e-58 196.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EDO06832.1 - 1.3e-37 128.0 0.0 2.7e-37 127.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EDO06832.1 - 6.4e-29 99.6 0.0 1.3e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EDO06832.1 - 1.9e-24 85.3 0.0 3.6e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDO06832.1 - 1e-16 60.7 0.2 2.3e-16 59.6 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO06832.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-MYND PF01753.13 EDO06833.1 - 4.8e-11 42.3 15.5 9.9e-11 41.3 10.8 1.5 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.2 EDO06833.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) TCTP PF00838.12 EDO06834.1 - 5.2e-44 150.1 0.6 6.1e-44 149.9 0.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Avl9 PF09794.4 EDO06835.1 - 3.2e-28 98.3 2.3 3.5e-24 84.9 1.2 3.2 2 1 0 2 2 2 2 Transport protein Avl9 MORN PF02493.15 EDO06835.1 - 2.2e-25 86.8 39.4 8.7e-05 22.0 1.1 10.8 11 0 0 11 11 11 8 MORN repeat DENN PF02141.16 EDO06835.1 - 0.19 11.4 2.6 8.8 6.0 0.2 2.5 2 0 0 2 2 2 0 DENN (AEX-3) domain CGI-121 PF08617.5 EDO06836.1 - 1.9e-26 92.6 2.2 2.4e-17 63.0 1.0 2.1 1 1 1 2 2 2 2 Kinase binding protein CGI-121 DUF416 PF04222.7 EDO06836.1 - 0.073 12.2 1.5 0.19 10.8 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF416) Voldacs PF03517.8 EDO06836.1 - 0.087 12.6 0.8 1.6 8.5 0.6 2.1 1 1 1 2 2 2 0 Regulator of volume decrease after cellular swelling VBS PF08913.5 EDO06836.1 - 0.12 12.6 0.3 0.34 11.1 0.2 1.7 1 1 0 1 1 1 0 Vinculin Binding Site DUF4217 PF13959.1 EDO06837.1 - 0.0047 16.4 0.0 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Colipase PF01114.13 EDO06838.1 - 0.11 11.9 0.4 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 Colipase, N-terminal domain Dus PF01207.12 EDO06839.1 - 6.2e-69 232.1 0.0 7.6e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EDO06839.1 - 3.8e-06 26.3 0.0 5.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 EDO06839.1 - 2.5e-05 23.4 0.0 3.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EDO06839.1 - 0.0054 15.6 0.0 0.0084 15.0 0.0 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain G3P_antiterm PF04309.7 EDO06839.1 - 0.055 12.5 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator NMO PF03060.10 EDO06839.1 - 0.057 12.5 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.16 EDO06839.1 - 0.12 11.2 0.0 0.59 9.0 0.0 2.0 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase GDH_N PF12466.3 EDO06840.1 - 0.071 13.1 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal Prefoldin_2 PF01920.15 EDO06841.1 - 4.4e-15 55.3 3.3 5e-15 55.1 2.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit ING PF12998.2 EDO06841.1 - 0.0012 19.1 2.6 0.0016 18.7 1.8 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Prefoldin_3 PF13758.1 EDO06841.1 - 0.003 17.3 1.3 0.008 15.9 0.9 1.7 1 1 0 1 1 1 1 Prefoldin subunit Syntaxin PF00804.20 EDO06841.1 - 0.0055 16.8 4.0 0.0094 16.0 2.7 1.4 1 1 0 1 1 1 1 Syntaxin DUF948 PF06103.6 EDO06841.1 - 0.014 15.2 3.5 0.11 12.3 0.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF342 PF03961.8 EDO06841.1 - 0.021 13.2 2.5 0.023 13.1 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) EzrA PF06160.7 EDO06841.1 - 0.038 12.1 5.7 0.072 11.2 3.9 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA MADF_DNA_bdg PF10545.4 EDO06841.1 - 0.058 13.5 0.2 12 6.1 0.0 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Atg14 PF10186.4 EDO06841.1 - 0.06 12.2 4.3 0.1 11.5 3.0 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 POLO_box PF00659.13 EDO06841.1 - 0.066 13.1 0.2 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 POLO box duplicated region ASD2 PF08687.6 EDO06841.1 - 0.079 12.2 2.6 0.11 11.8 1.8 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Lebercilin PF15619.1 EDO06841.1 - 0.098 12.0 2.6 0.16 11.3 1.8 1.3 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.1 EDO06841.1 - 0.12 10.8 3.3 0.13 10.6 2.3 1.0 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.7 EDO06841.1 - 0.13 12.5 2.5 13 6.1 1.8 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FliD_C PF07195.7 EDO06841.1 - 0.13 11.4 1.6 0.17 11.1 1.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF1664 PF07889.7 EDO06841.1 - 0.14 12.0 1.8 0.23 11.2 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PspA_IM30 PF04012.7 EDO06841.1 - 0.14 11.5 2.5 0.16 11.3 1.7 1.1 1 0 0 1 1 1 0 PspA/IM30 family Seryl_tRNA_N PF02403.17 EDO06841.1 - 0.14 12.1 3.5 1.8 8.6 2.4 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.12 EDO06841.1 - 0.14 11.7 5.3 0.45 10.1 0.7 2.1 2 0 0 2 2 2 0 Prefoldin subunit Tex_N PF09371.5 EDO06841.1 - 0.18 11.0 2.5 0.17 11.1 0.4 1.7 2 0 0 2 2 2 0 Tex-like protein N-terminal domain Ded_cyto PF06920.8 EDO06841.1 - 0.2 10.9 1.3 0.5 9.6 0.1 1.8 2 0 0 2 2 2 0 Dedicator of cytokinesis Osmo_CC PF08946.5 EDO06841.1 - 0.27 11.2 1.4 13 5.9 0.0 2.4 2 1 0 2 2 2 0 Osmosensory transporter coiled coil Tropomyosin_1 PF12718.2 EDO06841.1 - 0.3 10.9 5.3 1.7 8.5 3.7 1.8 1 1 0 1 1 1 0 Tropomyosin like Mnd1 PF03962.10 EDO06841.1 - 0.49 10.0 3.5 6.8 6.3 0.1 2.0 1 1 1 2 2 2 0 Mnd1 family Fib_alpha PF08702.5 EDO06841.1 - 0.59 10.2 4.4 0.74 9.9 3.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 EDO06841.1 - 0.7 10.2 4.5 1.3 9.4 0.2 2.1 1 1 0 2 2 2 0 Snapin/Pallidin Spc7 PF08317.6 EDO06841.1 - 1.2 7.6 6.2 2.2 6.8 4.3 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EDO06841.1 - 1.5 8.3 5.6 2.5 7.6 3.9 1.3 1 1 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.7 EDO06841.1 - 1.5 8.5 8.5 1.6 8.4 0.9 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GSH_synth_ATP PF03917.12 EDO06843.1 - 1.8e-47 161.7 0.0 4.9e-47 160.2 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EDO06843.1 - 2e-13 50.3 0.0 1.7e-12 47.3 0.0 2.2 1 1 0 1 1 1 1 Eukaryotic glutathione synthase MATH PF00917.21 EDO06844.1 - 0.00018 21.7 0.1 0.0005 20.3 0.0 1.7 1 0 0 1 1 1 1 MATH domain 2-oxoacid_dh PF00198.18 EDO06845.1 - 4.3e-76 255.1 0.1 5.7e-76 254.8 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EDO06845.1 - 1.4e-17 63.1 1.8 3.1e-17 61.9 1.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.14 EDO06845.1 - 0.001 18.7 0.3 0.0023 17.6 0.2 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein Nsp1_C PF05064.8 EDO06846.1 - 0.048 13.2 0.1 0.33 10.5 0.1 2.2 2 1 1 3 3 3 0 Nsp1-like C-terminal region DUF3681 PF12442.3 EDO06851.1 - 0.17 12.0 1.5 0.24 11.6 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) ABC_tran PF00005.22 EDO06852.1 - 6.7e-30 104.1 0.0 1.1e-28 100.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EDO06852.1 - 7e-30 104.3 0.1 1e-29 103.8 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EDO06852.1 - 0.00012 21.4 0.0 0.03 13.5 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDO06852.1 - 0.0012 18.8 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDO06852.1 - 0.0057 16.8 0.1 0.046 13.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO06852.1 - 0.0085 16.0 0.2 0.03 14.2 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.12 EDO06852.1 - 0.038 13.8 0.2 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_13 PF13166.1 EDO06852.1 - 0.043 12.2 0.2 2.6 6.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Bax1-I PF01027.15 EDO06852.1 - 0.054 13.0 3.5 0.34 10.4 0.7 2.2 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 AAA_29 PF13555.1 EDO06852.1 - 0.069 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.17 EDO06852.1 - 0.098 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EDO06852.1 - 0.17 11.8 0.0 4.2 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Laminin_G_3 PF13385.1 EDO06854.1 - 0.0013 19.0 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Thg1C PF14413.1 EDO06857.1 - 3.5e-40 136.4 0.0 5.6e-40 135.7 0.0 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EDO06857.1 - 3.8e-31 107.5 0.1 3.4e-29 101.1 0.1 2.2 1 1 0 1 1 1 1 tRNAHis guanylyltransferase DNA_pol3_beta_2 PF02767.11 EDO06857.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain MBOAT PF03062.14 EDO06858.1 - 1.4e-16 60.4 24.8 1.4e-16 60.4 17.2 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Tropomyosin_1 PF12718.2 EDO06859.1 - 0.0081 16.0 51.3 0.036 13.9 1.4 5.1 2 1 3 5 5 5 4 Tropomyosin like IncA PF04156.9 EDO06859.1 - 0.01 15.4 57.1 2.4 7.6 10.7 4.7 2 1 3 5 5 5 0 IncA protein Reo_sigmaC PF04582.7 EDO06859.1 - 0.018 14.2 17.1 0.92 8.6 1.9 3.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein ATG16 PF08614.6 EDO06859.1 - 0.023 14.5 47.9 2.3 8.0 5.2 4.5 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 EDO06859.1 - 0.025 14.9 1.7 0.025 14.9 1.2 6.1 2 1 4 6 6 6 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 EDO06859.1 - 0.061 13.1 54.2 0.1 12.4 12.1 5.2 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EDO06859.1 - 0.12 10.0 52.3 0.13 9.9 5.4 3.9 2 1 1 3 3 3 0 Myosin tail WEMBL PF05701.6 EDO06859.1 - 0.17 10.3 47.4 0.5 8.7 18.8 3.1 2 1 1 3 3 3 0 Weak chloroplast movement under blue light DUF869 PF05911.6 EDO06859.1 - 0.27 9.4 41.1 1.1 7.4 21.7 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Filament PF00038.16 EDO06859.1 - 0.39 10.1 48.9 2.9 7.2 16.3 4.3 2 1 1 4 4 4 0 Intermediate filament protein CALCOCO1 PF07888.6 EDO06859.1 - 1 7.5 42.2 1.9 6.7 4.4 3.4 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like EzrA PF06160.7 EDO06859.1 - 1.7 6.7 37.3 0.14 10.2 10.8 3.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA ADIP PF11559.3 EDO06859.1 - 1.8 8.4 55.0 0.43 10.4 4.9 5.6 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding YlqD PF11068.3 EDO06859.1 - 2.2 8.3 39.9 0.34 10.9 0.2 5.3 3 1 2 5 5 5 0 YlqD protein FlaC_arch PF05377.6 EDO06859.1 - 2.2 8.2 23.8 28 4.6 0.0 7.7 4 3 3 7 7 7 0 Flagella accessory protein C (FlaC) GAS PF13851.1 EDO06859.1 - 2.5 7.2 51.3 0.07 12.3 9.2 4.7 2 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EDO06859.1 - 3.7 7.3 23.0 0.62 9.8 2.0 4.7 2 1 2 5 5 5 0 Protein of unknown function (DUF1664) APG6 PF04111.7 EDO06859.1 - 3.8 6.4 52.3 0.11 11.5 11.5 4.1 2 1 3 5 5 5 0 Autophagy protein Apg6 WXG100 PF06013.7 EDO06859.1 - 4.3 7.4 20.7 0.26 11.3 0.2 6.1 3 2 3 7 7 7 0 Proteins of 100 residues with WXG BLOC1_2 PF10046.4 EDO06859.1 - 5 7.3 32.8 3.7 7.7 3.1 6.9 4 2 2 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.6 EDO06859.1 - 5.5 5.5 46.3 0.78 8.3 9.7 4.1 2 1 2 4 4 4 0 Spc7 kinetochore protein Hemerythrin PF01814.18 EDO06859.1 - 8 6.6 11.8 27 4.9 0.1 4.2 1 1 3 4 4 4 0 Hemerythrin HHE cation binding domain mRNA_triPase PF02940.10 EDO06860.1 - 1.5e-39 135.9 0.1 2e-39 135.5 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Pro_isomerase PF00160.16 EDO06861.1 - 2.7e-46 157.6 0.3 3.2e-46 157.3 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CPSF_A PF03178.10 EDO06862.1 - 6.5e-40 137.1 1.2 4.8e-38 131.0 0.7 3.1 2 1 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EDO06862.1 - 2.6e-13 48.9 0.2 6.1e-12 44.4 0.0 2.4 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Utp21 PF04192.7 EDO06863.1 - 4.3e-24 84.9 0.0 5.9e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EDO06863.1 - 6e-08 32.2 10.4 0.00021 21.0 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EDO06863.1 - 0.0014 18.1 0.1 0.46 9.9 0.0 3.1 2 1 0 2 2 2 2 PQQ-like domain Hira PF07569.6 EDO06863.1 - 0.011 14.9 1.0 8.2 5.5 0.0 3.4 3 0 0 3 3 3 0 TUP1-like enhancer of split Cpn60_TCP1 PF00118.19 EDO06864.1 - 5e-141 470.6 18.8 5.6e-141 470.4 13.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.27 EDO06865.1 - 0.0019 17.9 3.8 0.13 12.1 1.1 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-CCCH_2 PF14608.1 EDO06865.1 - 0.0089 15.9 1.7 0.024 14.6 1.2 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type RRM_1 PF00076.17 EDO06867.1 - 1.3e-15 56.7 0.0 2.4e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06867.1 - 4e-10 39.5 0.0 6.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06867.1 - 0.00013 21.7 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 EDO06868.1 - 6.6e-10 39.1 3.2 0.0012 18.6 0.1 3.4 2 2 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EDO06868.1 - 4e-09 36.2 0.0 0.067 13.8 0.0 4.4 2 1 2 4 4 4 3 Tetratricopeptide repeat NRDE-2 PF08424.5 EDO06868.1 - 0.00026 19.9 1.4 0.27 10.0 0.1 3.5 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference TPR_19 PF14559.1 EDO06868.1 - 0.00045 20.4 0.0 0.061 13.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO06868.1 - 0.0084 16.7 0.0 2.4 8.9 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDO06868.1 - 0.0097 15.7 0.0 0.59 10.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDO06868.1 - 0.032 13.8 0.0 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.15 EDO06868.1 - 0.034 14.1 0.5 1.4 9.0 0.0 3.4 3 0 0 3 3 3 0 PPR repeat TPR_11 PF13414.1 EDO06868.1 - 0.063 12.9 0.0 1.2 8.8 0.0 2.4 1 1 1 2 2 2 0 TPR repeat S1 PF00575.18 EDO06869.1 - 9.5e-07 28.8 8.3 0.00059 19.8 0.0 4.1 4 0 0 4 4 4 3 S1 RNA binding domain PCI PF01399.22 EDO06870.1 - 0.0057 16.9 0.0 0.0057 16.9 0.0 4.1 4 1 1 5 5 5 1 PCI domain Dynein_light PF01221.13 EDO06871.1 - 1.7e-37 127.3 0.3 1.9e-37 127.1 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RNA_pol_Rpb8 PF03870.10 EDO06872.1 - 8.1e-35 120.0 0.6 9.1e-35 119.8 0.4 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 GerPC PF10737.4 EDO06873.1 - 0.014 15.2 0.2 0.019 14.7 0.1 1.2 1 0 0 1 1 1 0 Spore germination protein GerPC Aconitase_B_N PF11791.3 EDO06873.1 - 0.051 13.3 0.5 0.071 12.9 0.3 1.2 1 0 0 1 1 1 0 Aconitate B N-terminal domain PTH2 PF01981.11 EDO06873.1 - 0.08 12.6 0.3 6.9 6.3 0.0 2.1 1 1 1 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 Sof1 PF04158.9 EDO06874.1 - 2.9e-26 91.3 10.7 4.7e-26 90.6 7.4 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.27 EDO06874.1 - 8.6e-26 88.8 9.3 3.3e-05 23.5 0.2 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EDO06874.1 - 0.00023 20.9 0.1 0.0097 15.6 0.0 2.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A HECT PF00632.20 EDO06876.1 - 2.3e-91 306.2 0.0 4.1e-91 305.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 EDO06876.1 - 1.6e-54 185.1 0.0 5e-54 183.4 0.0 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 EDO06876.1 - 1.6e-35 122.9 8.2 4.9e-35 121.4 5.7 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EDO06876.1 - 8.5e-13 48.1 0.0 2.3e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) EF-hand_8 PF13833.1 EDO06877.1 - 4.8e-28 96.5 12.3 2.9e-12 45.9 0.7 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 EDO06877.1 - 2.9e-27 91.8 10.6 3.1e-07 29.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EDO06877.1 - 1.1e-23 83.1 6.7 3.7e-11 42.9 2.3 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EDO06877.1 - 1.3e-23 80.6 6.2 4.2e-07 29.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EDO06877.1 - 3.1e-15 54.7 10.9 0.00012 21.2 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 EDO06877.1 - 8.8e-15 54.3 0.1 2e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EDO06877.1 - 0.00017 21.2 2.9 0.43 10.3 0.0 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Toprim_2 PF13155.1 EDO06877.1 - 0.0041 17.4 2.5 0.26 11.6 0.0 2.9 1 1 1 3 3 3 1 Toprim-like Ribosomal_L50 PF10501.4 EDO06877.1 - 0.037 13.9 0.0 0.066 13.1 0.0 1.6 1 1 0 1 1 1 0 Ribosomal subunit 39S SHS2_Rpb7-N PF03876.12 EDO06878.1 - 8.3e-16 57.8 0.0 1.4e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EDO06878.1 - 7.8e-08 32.2 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain AhpC-TSA PF00578.16 EDO06879.1 - 3.6e-16 58.9 0.0 4.4e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EDO06879.1 - 1.2e-11 44.3 0.0 1.6e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin Rsm22 PF09243.5 EDO06880.1 - 3.8e-08 32.7 0.0 5.5e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Acyltransferase PF01553.16 EDO06881.1 - 3.1e-16 58.9 0.0 1.6e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase DUF872 PF05915.7 EDO06881.1 - 0.018 14.9 0.6 0.039 13.8 0.4 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) TPR_2 PF07719.12 EDO06882.1 - 4.4e-15 54.2 2.3 4.1e-05 23.1 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EDO06882.1 - 1.4e-13 50.2 3.7 4.2e-10 39.1 3.3 2.5 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EDO06882.1 - 1.5e-13 49.7 2.7 5.7e-06 25.7 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDO06882.1 - 1e-11 45.1 0.9 1.8e-09 37.9 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDO06882.1 - 7.2e-10 38.6 0.7 4.8e-05 23.6 0.0 3.7 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDO06882.1 - 1.5e-07 31.6 0.2 0.0045 17.2 0.0 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO06882.1 - 3.6e-07 29.5 4.3 0.0067 16.1 0.1 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDO06882.1 - 7.8e-07 28.4 1.7 0.0098 15.6 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO06882.1 - 1.4e-06 28.1 3.9 4.6e-06 26.4 2.7 1.9 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDO06882.1 - 1.7e-05 24.5 4.0 0.088 12.7 0.4 2.6 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 EDO06882.1 - 0.00013 21.9 14.1 0.0036 17.4 2.1 2.1 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EDO06882.1 - 0.00029 20.8 3.8 0.92 9.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDO06882.1 - 0.002 18.4 0.6 5.1 7.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EDO06882.1 - 0.027 14.3 0.2 0.77 9.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 EDO06882.1 - 0.034 14.2 0.8 4.1 7.5 0.1 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 EDO06882.1 - 0.042 13.6 0.2 4 7.3 0.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 EDO06882.1 - 0.047 13.5 0.1 35 4.2 0.0 3.3 2 1 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region Lumazine_bd PF12870.2 EDO06882.1 - 0.066 13.2 0.9 5 7.2 0.0 2.5 2 1 1 3 3 2 0 Lumazine-binding domain Alkyl_sulf_dimr PF14863.1 EDO06882.1 - 0.1 12.8 0.2 0.46 10.7 0.0 1.9 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation Metallophos PF00149.23 EDO06883.1 - 1.7e-28 99.3 0.2 2.9e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.1 EDO06883.1 - 3.7e-19 68.6 3.7 2.6e-07 30.6 0.1 5.2 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.27 EDO06883.1 - 1.1e-12 46.2 0.5 0.036 13.3 0.0 6.6 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 EDO06883.1 - 1.8e-10 39.8 1.6 0.0079 15.9 0.0 6.1 6 0 0 6 6 6 3 EF-hand domain EF-hand_8 PF13833.1 EDO06883.1 - 5e-09 35.6 0.9 0.0002 20.9 0.0 4.0 3 1 0 3 3 3 2 EF-hand domain pair IQ PF00612.22 EDO06883.1 - 0.00054 19.3 1.6 0.0013 18.1 1.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif PPP5 PF08321.7 EDO06883.1 - 0.0071 16.3 1.5 0.064 13.2 0.0 3.3 4 0 0 4 4 4 1 PPP5 TPR repeat region MS_channel PF00924.13 EDO06883.1 - 0.07 12.4 0.3 0.18 11.0 0.2 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel CNH PF00780.17 EDO06884.1 - 3.8e-08 33.0 0.1 9.5e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 EDO06884.1 - 0.00017 21.7 3.2 0.0002 21.4 0.0 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EDO06884.1 - 0.008 15.7 3.3 0.008 15.7 2.3 3.0 3 0 0 3 3 3 1 Region in Clathrin and VPS DUF2392 PF10288.4 EDO06884.1 - 0.046 14.0 0.2 0.26 11.6 0.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) Desmo_N PF06771.6 EDO06884.1 - 0.06 13.2 0.3 0.06 13.2 0.2 2.6 3 0 0 3 3 3 0 Viral Desmoplakin N-terminus Vps39_1 PF10366.4 EDO06884.1 - 5.4 7.0 12.0 7.1 6.7 1.9 3.0 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 Pkinase PF00069.20 EDO06885.1 - 8.9e-05 21.7 0.2 0.0023 17.1 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain PRESAN PF09687.5 EDO06885.1 - 0.087 12.8 9.6 1.8 8.6 0.6 2.7 2 0 0 2 2 2 0 Plasmodium RESA N-terminal BCIP PF13862.1 EDO06886.1 - 3.9e-42 143.9 0.0 6.5e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein RF-1 PF00472.15 EDO06887.1 - 1.2e-20 73.4 3.0 3.3e-20 72.0 2.1 1.7 1 1 0 1 1 1 1 RF-1 domain DUF3734 PF12536.3 EDO06887.1 - 0.054 13.6 2.8 0.094 12.8 2.0 1.3 1 0 0 1 1 1 0 Patatin phospholipase TPR_2 PF07719.12 EDO06887.1 - 1.5 8.9 3.5 16 5.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.24 EDO06888.1 - 1.4e-14 53.9 0.0 6.5e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO06888.1 - 1.9e-12 46.8 0.1 5.2e-12 45.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Methyltransf_18 PF12847.2 EDO06888.1 - 0.0044 17.5 0.1 1.5 9.4 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_32 PF13679.1 EDO06888.1 - 0.0061 16.2 0.0 0.037 13.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ResIII PF04851.10 EDO06888.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Methyltransf_11 PF08241.7 EDO06888.1 - 0.021 15.2 0.0 1.2 9.7 0.0 3.0 2 0 0 2 2 2 0 Methyltransferase domain LCM PF04072.9 EDO06888.1 - 0.086 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase Fer2_3 PF13085.1 EDO06889.1 - 2.6e-34 117.3 0.1 4.3e-34 116.6 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EDO06889.1 - 1.3e-10 41.4 5.8 1.3e-10 41.4 4.0 2.5 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EDO06889.1 - 5.4e-08 32.7 5.5 5.4e-08 32.7 3.8 2.7 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EDO06889.1 - 2e-07 31.3 2.3 2e-07 31.3 1.6 3.1 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EDO06889.1 - 1.8e-05 24.3 5.9 1.8e-05 24.3 4.1 3.1 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EDO06889.1 - 0.00026 21.2 14.1 0.0068 16.6 0.4 3.7 3 1 0 3 3 3 2 4Fe-4S dicluster domain SAA PF00277.13 EDO06889.1 - 0.006 16.9 0.1 0.01 16.1 0.1 1.3 1 0 0 1 1 1 1 Serum amyloid A protein Fer4_7 PF12838.2 EDO06889.1 - 0.011 16.0 8.1 0.011 16.0 5.6 3.4 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer2 PF00111.22 EDO06889.1 - 0.012 15.3 2.7 0.012 15.3 1.9 2.4 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_21 PF14697.1 EDO06889.1 - 1.2 9.0 14.3 5.4 6.9 1.4 3.6 3 1 0 3 3 3 0 4Fe-4S dicluster domain Bromodomain PF00439.20 EDO06890.1 - 4.6e-15 55.2 0.0 1.1e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain DUF1674 PF07896.7 EDO06892.1 - 4.3e-07 30.0 0.1 6.5e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Virulence_fact PF13769.1 EDO06893.1 - 0.018 14.8 0.1 0.061 13.1 0.0 1.8 2 0 0 2 2 2 0 Virulence factor Ndc80_HEC PF03801.8 EDO06894.1 - 4.8e-23 81.3 0.1 1.2e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family SnoaL PF07366.7 EDO06894.1 - 0.016 14.7 0.0 7.6 6.1 0.0 2.9 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase PTH2 PF01981.11 EDO06894.1 - 0.43 10.2 0.0 0.43 10.2 0.0 2.9 2 1 2 4 4 4 0 Peptidyl-tRNA hydrolase PTH2 WD40 PF00400.27 EDO06895.1 - 6.5e-36 120.9 4.5 1.6e-07 30.9 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EDO06895.1 - 1.6e-05 23.8 3.1 0.042 12.5 0.3 3.3 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 EDO06895.1 - 0.014 13.5 0.1 1.9 6.5 0.0 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EDO06895.1 - 0.073 13.3 0.1 10 6.5 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain ATP-synt PF00231.14 EDO06896.1 - 3.4e-79 266.2 0.1 3.9e-79 266.0 0.1 1.0 1 0 0 1 1 1 1 ATP synthase Ribosomal_S9 PF00380.14 EDO06897.1 - 7.2e-38 129.5 0.3 8.3e-38 129.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.13 EDO06898.1 - 1.5e-44 151.5 2.1 2e-44 151.2 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e DUF4473 PF14747.1 EDO06898.1 - 0.072 13.3 0.5 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) FAINT PF04385.10 EDO06900.1 - 0.021 14.6 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Tim54 PF11711.3 EDO06900.1 - 5.9 5.3 12.5 13 4.2 5.5 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 GTP_EFTU PF00009.22 EDO06901.1 - 7.9e-53 178.6 0.1 1.2e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EDO06901.1 - 1.1e-10 41.2 0.0 2.6e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EDO06901.1 - 7.9e-06 25.8 0.0 2.5e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDO06901.1 - 0.0002 21.8 0.0 0.00047 20.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EDO06901.1 - 0.0016 17.6 0.4 0.003 16.6 0.0 1.6 2 0 0 2 2 2 1 AIG1 family CbiA PF01656.18 EDO06901.1 - 0.0095 15.3 0.1 0.045 13.1 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Septin PF00735.13 EDO06901.1 - 0.053 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Septin MobB PF03205.9 EDO06901.1 - 0.081 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SBDS PF01172.13 EDO06902.1 - 8.6e-32 108.7 0.5 1.6e-31 107.9 0.4 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 EDO06902.1 - 4.1e-24 84.6 0.3 7.6e-24 83.8 0.2 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain zf-C2H2_jaz PF12171.3 EDO06902.1 - 0.078 13.1 1.0 0.19 11.9 0.7 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding ING PF12998.2 EDO06903.1 - 1.3e-06 28.6 1.8 0.00027 21.1 1.2 2.4 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding FAM75 PF14650.1 EDO06903.1 - 0.027 13.8 3.8 0.051 12.9 2.7 1.4 1 0 0 1 1 1 0 FAM75 family SOG2 PF10428.4 EDO06903.1 - 0.077 11.6 10.6 0.097 11.3 7.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RAP PF08373.5 EDO06904.1 - 1.4e-07 31.2 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 RAP domain DUF3797 PF12677.2 EDO06905.1 - 0.0047 16.5 0.2 0.009 15.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3797) Ribosomal_S13 PF00416.17 EDO06906.1 - 2.8e-35 120.9 1.6 3.4e-35 120.7 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EDO06906.1 - 0.0076 14.8 0.0 0.0076 14.8 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_L5_C PF00673.16 EDO06907.1 - 2.1e-25 88.2 0.1 2.9e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EDO06907.1 - 9.3e-17 60.5 0.0 2.1e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 CCDC-167 PF15188.1 EDO06908.1 - 1.1 9.2 4.9 30 4.6 1.6 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 HTH_38 PF13936.1 EDO06908.1 - 4.2 6.9 7.8 3.9 7.0 0.1 3.2 4 0 0 4 4 4 0 Helix-turn-helix domain Actin PF00022.14 EDO06909.1 - 1.3e-61 208.1 0.0 2.9e-61 207.0 0.0 1.4 1 1 0 1 1 1 1 Actin CDC50 PF03381.10 EDO06910.1 - 2.4e-36 125.3 0.2 3.1e-36 124.9 0.2 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family WD40 PF00400.27 EDO06912.1 - 1.6e-06 27.7 16.1 1.4e-05 24.8 0.3 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Pkinase PF00069.20 EDO06913.1 - 3.7e-61 206.5 0.1 3.3e-39 134.5 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO06913.1 - 1.5e-28 99.5 0.0 2.6e-23 82.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase YokU PF14122.1 EDO06913.1 - 0.12 12.0 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 YokU-like protein Kinase-like PF14531.1 EDO06913.1 - 0.13 11.1 0.0 0.61 8.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like WD40 PF00400.27 EDO06914.1 - 5.6e-26 89.4 13.0 1.6e-05 24.5 0.1 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EDO06914.1 - 0.012 15.2 0.0 0.85 9.2 0.0 2.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PQQ PF01011.16 EDO06914.1 - 0.036 13.6 0.2 0.11 12.0 0.1 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat RabGAP-TBC PF00566.13 EDO06915.1 - 5e-50 169.9 0.5 9e-50 169.1 0.4 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RAP PF08373.5 EDO06916.1 - 0.00012 21.8 1.7 0.00022 20.9 0.0 2.1 2 0 0 2 2 2 1 RAP domain IMPDH PF00478.20 EDO06917.1 - 6.3e-75 252.2 0.9 1.5e-74 251.0 0.6 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EDO06917.1 - 1.2e-07 30.9 0.7 3.6e-06 26.0 0.2 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EDO06917.1 - 0.0088 15.0 0.7 0.015 14.2 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase Peptidase_M24 PF00557.19 EDO06918.1 - 1.1e-27 96.9 0.7 1.5e-27 96.5 0.5 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 BHD_1 PF10403.4 EDO06920.1 - 1.2e-10 40.7 0.0 4.5e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.4 EDO06920.1 - 6.3e-07 29.0 0.0 1.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 EDO06920.1 - 0.002 18.4 0.0 0.0084 16.4 0.0 2.2 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Methyltrn_RNA_3 PF02598.12 EDO06921.1 - 2.3e-51 174.9 0.0 8.5e-39 133.6 0.0 3.0 2 1 0 2 2 2 2 Putative RNA methyltransferase Ubiquitin_2 PF14560.1 EDO06922.1 - 9.3e-22 77.0 1.7 2.8e-21 75.5 0.0 2.3 3 0 0 3 3 3 1 Ubiquitin-like domain CAP_GLY PF01302.20 EDO06922.1 - 2.5e-15 55.9 0.4 4.1e-15 55.2 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.18 EDO06922.1 - 0.00026 20.3 1.2 0.096 12.0 0.0 3.3 4 0 0 4 4 4 2 Ubiquitin family Tcp10_C PF07202.8 EDO06922.1 - 0.054 13.0 0.1 0.086 12.3 0.1 1.3 1 0 0 1 1 1 0 T-complex protein 10 C-terminus Ribosomal_L13 PF00572.13 EDO06923.1 - 2.4e-15 56.7 0.0 3.4e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Helicase_Sgs1 PF11408.3 EDO06924.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Sgs1 RecQ helicase Peptidase_S49_N PF08496.5 EDO06924.1 - 6.6 6.5 5.7 18 5.1 0.0 2.9 3 0 0 3 3 3 0 Peptidase family S49 N-terminal TMEM156 PF15106.1 EDO06924.1 - 7.7 5.6 7.2 6.6 5.8 0.3 3.1 3 0 0 3 3 3 0 TMEM156 protein family VESA1_N PF12785.2 EDO06925.1 - 1.9e-11 43.6 6.8 2.3e-11 43.3 4.7 1.0 1 0 0 1 1 1 1 Variant erythrocyte surface antigen-1 TIG PF01833.19 EDO06925.1 - 0.14 12.1 3.2 0.22 11.5 2.2 1.3 1 0 0 1 1 1 0 IPT/TIG domain CBF_beta PF02312.12 EDO06925.1 - 0.15 11.6 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Core binding factor beta subunit LMP PF04778.7 EDO06927.1 - 0.032 13.9 2.1 0.072 12.8 1.1 1.7 1 1 1 2 2 2 0 LMP repeated region DUF869 PF05911.6 EDO06927.1 - 0.05 11.8 3.7 0.062 11.5 2.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 EDO06927.1 - 0.054 12.6 3.5 0.078 12.1 2.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF2616 PF11077.3 EDO06927.1 - 0.12 11.8 4.0 0.052 13.0 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) VESA1_N PF12785.2 EDO06928.1 - 2.3e-24 86.2 13.0 2.3e-24 86.2 9.0 4.6 3 1 1 4 4 4 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO06929.1 - 3.4e-221 735.1 20.6 3.4e-221 735.1 14.3 2.5 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 DUF4175 PF13779.1 EDO06929.1 - 0.019 12.6 1.3 0.03 12.0 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Abhydrolase_5 PF12695.2 EDO06930.1 - 2.2e-16 59.9 0.0 2.9e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO06930.1 - 0.00037 20.4 0.4 0.0049 16.7 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO06930.1 - 0.00044 19.8 0.0 0.00067 19.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDO06930.1 - 0.025 13.8 0.0 0.05 12.8 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 EDO06930.1 - 0.048 13.5 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.8 EDO06930.1 - 0.062 12.7 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EDO06930.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ribosomal_L13 PF00572.13 EDO06931.1 - 1e-37 129.0 0.1 1.3e-37 128.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 TipAS PF07739.8 EDO06932.1 - 0.18 12.1 2.8 4.6 7.5 0.0 3.3 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain Sec23_trunk PF04811.10 EDO06934.1 - 2.8e-16 59.6 0.0 4.6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EDO06934.1 - 7e-15 55.3 0.2 1.6e-14 54.1 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 EDO06934.1 - 1.8e-08 33.7 0.1 5.7e-08 32.1 0.1 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EDO06934.1 - 2.7e-07 30.0 1.3 7e-07 28.7 0.9 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EDO06934.1 - 0.00012 21.6 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Coleoptericin PF06286.6 EDO06934.1 - 0.018 14.9 0.3 0.04 13.8 0.2 1.5 1 0 0 1 1 1 0 Coleoptericin DEAD PF00270.24 EDO06935.1 - 2.8e-22 78.9 0.0 4.5e-20 71.8 0.0 2.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO06935.1 - 2.3e-21 75.4 0.1 5.9e-21 74.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LSM PF01423.17 EDO06937.1 - 3.2e-17 61.8 0.0 4.4e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDO06937.1 - 1.1e-05 25.2 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain dUTPase PF00692.14 EDO06938.1 - 9e-19 67.2 0.0 3.4e-17 62.0 0.0 2.0 1 1 0 1 1 1 1 dUTPase Rhomboid PF01694.17 EDO06940.1 - 3.3e-13 49.8 9.1 3.3e-13 49.8 6.3 1.7 2 0 0 2 2 2 1 Rhomboid family DnaJ PF00226.26 EDO06941.1 - 0.0012 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DNA_pol_A PF00476.15 EDO06942.1 - 4.7e-62 209.8 0.1 6.5e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EDO06942.1 - 6.8e-27 94.0 0.0 1.2e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease AAA_25 PF13481.1 EDO06942.1 - 1.4e-22 80.0 0.0 3.6e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO06942.1 - 1.8e-06 28.0 0.0 6.1e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain Toprim_4 PF13662.1 EDO06942.1 - 1.5e-05 24.9 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Toprim domain KaiC PF06745.8 EDO06942.1 - 0.00042 19.5 0.0 0.00085 18.4 0.0 1.5 1 0 0 1 1 1 1 KaiC Toprim_3 PF13362.1 EDO06942.1 - 0.00045 20.4 0.0 0.0021 18.2 0.0 2.2 2 0 0 2 2 2 1 Toprim domain Toprim_2 PF13155.1 EDO06942.1 - 0.00087 19.5 0.0 0.0024 18.1 0.0 1.8 1 0 0 1 1 1 1 Toprim-like AAA_17 PF13207.1 EDO06942.1 - 0.03 15.1 0.0 0.15 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EDO06942.1 - 0.046 13.7 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EDO06942.1 - 0.12 12.6 1.7 1.6 9.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.1 EDO06942.1 - 0.19 11.3 0.7 0.63 9.6 0.2 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain MA3 PF02847.12 EDO06943.1 - 1.3e-10 40.9 7.0 7e-09 35.3 0.0 3.2 3 0 0 3 3 3 2 MA3 domain ATP-synt_ab PF00006.20 EDO06944.1 - 3.9e-65 219.3 0.0 1.2e-64 217.8 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDO06944.1 - 1.4e-21 77.0 0.5 2.4e-21 76.2 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDO06944.1 - 5.6e-19 68.1 0.1 1.2e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain MobB PF03205.9 EDO06944.1 - 0.0033 17.1 0.3 5.9 6.5 0.1 3.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EDO06944.1 - 0.0085 16.2 0.2 0.34 11.1 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDO06944.1 - 0.013 14.9 0.1 0.032 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EDO06944.1 - 0.014 14.5 0.1 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KaiC PF06745.8 EDO06944.1 - 0.044 12.9 0.5 0.081 12.0 0.4 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EDO06944.1 - 0.057 13.0 0.2 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 EDO06944.1 - 0.063 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 EDO06944.1 - 0.063 12.1 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EDO06944.1 - 0.13 12.2 0.1 0.44 10.5 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain SHMT PF00464.14 EDO06945.1 - 1.4e-174 580.1 0.0 1.6e-174 579.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase HTH_25 PF13413.1 EDO06945.1 - 0.065 12.8 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MT-A70 PF05063.9 EDO06946.1 - 4e-33 114.4 0.3 1.2e-22 80.3 0.1 2.7 1 1 1 2 2 2 2 MT-A70 Med26 PF08711.6 EDO06947.1 - 6.3e-11 41.6 0.1 1.2e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ribosomal_L35p PF01632.14 EDO06949.1 - 5e-14 51.9 11.0 5e-14 51.9 7.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L35 Coatomer_WDAD PF04053.9 EDO06950.1 - 9.9e-102 340.9 0.0 2.7e-101 339.5 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EDO06950.1 - 3.2e-38 128.2 19.1 2.6e-09 36.5 0.1 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat Snf7 PF03357.16 EDO06951.1 - 9.1e-12 44.6 9.3 1.2e-11 44.3 6.4 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EDO06951.1 - 0.009 15.4 6.3 0.017 14.4 3.4 1.9 1 1 1 2 2 2 1 Regulator of Vps4 activity in the MVB pathway DUF4230 PF14014.1 EDO06951.1 - 0.71 9.7 5.3 1.6 8.5 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4230) RNB PF00773.14 EDO06952.1 - 1.4e-81 274.3 0.5 2.3e-81 273.6 0.4 1.3 1 0 0 1 1 1 1 RNB domain Exo_endo_phos PF03372.18 EDO06953.1 - 3.9e-12 46.6 0.2 3e-10 40.4 0.2 2.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3458 PF11940.3 EDO06954.1 - 9.9e-93 310.8 0.1 4.1e-49 167.3 0.2 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 EDO06954.1 - 6.9e-62 209.7 0.0 9.7e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 EDO06954.1 - 1.6e-14 54.0 0.0 3.9e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily LcrR PF09621.5 EDO06954.1 - 0.12 11.5 0.1 17 4.7 0.0 2.4 2 0 0 2 2 2 0 Type III secretion system regulator (LcrR) RNase_PH PF01138.16 EDO06955.1 - 1.5e-19 70.6 0.7 3.1e-19 69.5 0.1 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EDO06955.1 - 0.01 15.7 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 LRR_4 PF12799.2 EDO06957.1 - 3.4e-14 52.0 9.6 5.1e-06 25.9 0.2 4.5 2 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDO06957.1 - 4.6e-13 48.7 5.9 2.1e-06 27.3 0.6 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.1 EDO06957.1 - 6.6e-10 38.8 1.1 2.8e-07 30.2 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 EDO06957.1 - 0.001 18.8 5.3 5.9 7.5 0.1 5.5 6 0 0 6 6 6 1 Leucine rich repeat LRR_1 PF00560.28 EDO06957.1 - 0.0022 17.7 3.5 14 6.2 0.1 4.5 4 1 1 5 5 5 2 Leucine Rich Repeat Merozoite_SPAM PF07133.6 EDO06957.1 - 6.6 6.6 26.1 14 5.5 18.1 1.6 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) LRR_6 PF13516.1 EDO06957.1 - 9.3 6.6 10.6 20 5.6 0.4 4.4 5 1 1 6 6 6 0 Leucine Rich repeat Wbp11 PF09429.5 EDO06958.1 - 4.6e-16 58.5 11.7 4.6e-16 58.5 8.1 1.7 2 0 0 2 2 2 1 WW domain binding protein 11 DUF2956 PF11169.3 EDO06958.1 - 5.3 7.0 12.0 0.87 9.5 3.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2956) BTV_NS2 PF04514.7 EDO06958.1 - 6 5.6 12.6 8 5.2 8.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Complex1_30kDa PF00329.14 EDO06959.1 - 0.079 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit AKAP95 PF04988.7 EDO06959.1 - 0.34 10.6 3.1 0.34 10.6 0.2 2.2 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) HTH_20 PF12840.2 EDO06960.1 - 0.082 12.7 0.1 0.57 10.0 0.0 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain MFS_1 PF07690.11 EDO06961.1 - 4.9e-13 48.5 48.2 2.3e-11 43.0 25.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rota_NS26 PF01525.11 EDO06961.1 - 0.75 9.5 4.5 1.2 8.9 3.1 1.2 1 0 0 1 1 1 0 Rotavirus NS26 Asn_synthase PF00733.16 EDO06963.1 - 1e-25 90.7 0.0 2.2e-13 50.3 0.0 2.5 2 1 0 2 2 2 2 Asparagine synthase ThiI PF02568.9 EDO06963.1 - 0.0055 16.1 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) GATase_7 PF13537.1 EDO06963.1 - 0.008 15.9 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain HEAT PF02985.17 EDO06964.1 - 1.7e-05 24.4 3.4 0.14 12.3 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EDO06964.1 - 3.4e-05 24.0 0.0 0.43 10.9 0.0 3.2 1 1 1 2 2 2 2 HEAT repeats CLASP_N PF12348.3 EDO06964.1 - 0.087 12.1 0.8 9.1 5.5 0.1 2.5 1 1 0 2 2 2 0 CLASP N terminal Vac14_Fab1_bd PF12755.2 EDO06964.1 - 0.1 12.9 0.5 12 6.3 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Ribosomal_L6 PF00347.18 EDO06968.1 - 6.4e-27 93.8 6.2 9e-14 51.7 0.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S15 PF00312.17 EDO06969.1 - 1.9e-14 53.1 0.5 3.1e-14 52.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 TPR_11 PF13414.1 EDO06970.1 - 2e-17 62.5 0.1 1.6e-09 37.2 0.0 3.3 3 1 1 4 4 3 2 TPR repeat TPR_2 PF07719.12 EDO06970.1 - 7.5e-15 53.5 0.1 0.00047 19.8 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EDO06970.1 - 1.5e-14 52.8 1.7 0.00047 19.6 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDO06970.1 - 5.3e-13 47.7 0.3 0.00016 21.1 0.0 5.6 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDO06970.1 - 2.3e-10 40.1 0.0 0.0055 17.2 0.0 5.0 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDO06970.1 - 4.8e-10 39.6 0.0 0.00075 19.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO06970.1 - 4.2e-09 36.2 0.2 0.0057 16.5 0.1 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDO06970.1 - 1.1e-07 32.3 0.0 1.3e-05 25.6 0.0 2.9 2 1 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EDO06970.1 - 0.00013 22.0 0.1 0.015 15.3 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDO06970.1 - 0.00021 21.5 0.0 0.32 11.5 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDO06970.1 - 0.0036 17.0 0.0 11 6.1 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EDO06970.1 - 0.015 15.1 0.0 0.86 9.4 0.0 3.0 2 1 2 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.4 EDO06970.1 - 0.019 14.3 0.7 0.63 9.3 0.0 2.9 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_15 PF13429.1 EDO06970.1 - 0.021 13.8 0.0 2.5 7.0 0.0 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDO06970.1 - 0.045 13.9 2.0 13 6.2 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDO06970.1 - 0.12 12.3 0.1 0.43 10.5 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat RRM_1 PF00076.17 EDO06971.1 - 0.0005 19.6 0.0 0.00066 19.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06971.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_M6 PF05547.6 EDO06971.1 - 0.14 10.1 0.0 0.15 10.0 0.0 1.0 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Mito_fiss_reg PF05308.6 EDO06973.1 - 0.31 10.3 4.3 0.44 9.8 3.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Pkinase PF00069.20 EDO06975.1 - 1.6e-12 47.1 0.2 4.5e-12 45.6 0.2 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO06975.1 - 2.9e-07 29.8 0.3 1.2e-06 27.8 0.2 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RWD PF05773.17 EDO06975.1 - 3.8e-05 23.5 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 RWD domain RF-1 PF00472.15 EDO06976.1 - 2.9e-27 94.7 4.6 9.7e-27 93.0 3.2 1.9 1 1 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EDO06976.1 - 4.6e-11 42.4 0.1 1.9e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 PCRF domain Spore_III_AF PF09581.5 EDO06976.1 - 0.23 11.3 3.8 0.15 11.9 1.2 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) TBP PF00352.16 EDO06977.1 - 4.3e-26 90.1 1.9 3.7e-06 26.2 0.0 4.2 4 0 0 4 4 4 4 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EDO06977.1 - 0.0084 16.1 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3378) UFC1 PF08694.6 EDO06978.1 - 5.2e-75 250.3 0.1 5.9e-75 250.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.21 EDO06978.1 - 0.00064 19.1 0.1 0.0012 18.3 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO06978.1 - 0.0012 18.5 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDO06978.1 - 0.0061 16.4 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain MIF4G_like_2 PF09090.6 EDO06981.1 - 2.8e-05 23.4 1.7 3.7e-05 23.0 0.2 1.9 2 0 0 2 2 2 1 MIF4G like LRR_9 PF14580.1 EDO06983.1 - 1.8e-45 154.6 0.0 2.2e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EDO06983.1 - 2.5e-20 71.6 23.8 8.8e-09 34.7 0.3 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDO06983.1 - 3.7e-10 39.3 8.0 3.4e-09 36.3 1.4 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EDO06983.1 - 3.8e-07 29.2 7.8 0.41 10.8 0.1 5.2 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EDO06983.1 - 4.3e-06 26.0 6.2 1.4 9.4 0.2 4.9 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 EDO06983.1 - 0.0085 16.0 6.9 1.3 9.3 0.4 4.8 5 0 0 5 5 5 1 Leucine Rich repeat GCC2_GCC3 PF07699.8 EDO06984.1 - 5.6e-26 89.8 114.4 2e-10 40.0 3.6 11.8 12 0 0 12 12 12 9 GCC2 and GCC3 GCC2_GCC3 PF07699.8 EDO06985.1 - 3.3e-32 109.8 114.1 4e-10 39.1 2.3 12.2 11 1 2 13 13 13 10 GCC2 and GCC3 He_PIG PF05345.7 EDO06985.1 - 0.00088 19.2 0.3 0.0026 17.7 0.2 1.8 1 0 0 1 1 1 1 Putative Ig domain Tektin PF03148.9 EDO06985.1 - 0.6 8.6 0.6 0.98 7.8 0.4 1.2 1 0 0 1 1 1 0 Tektin family TMF_DNA_bd PF12329.3 EDO06985.1 - 1.3 8.8 2.3 3 7.7 1.6 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF1192 PF06698.6 EDO06985.1 - 7 6.5 3.2 30 4.5 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Tau95 PF09734.4 EDO06986.1 - 4.9e-36 124.6 1.0 2.2e-35 122.4 0.1 2.2 2 1 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HEAT PF02985.17 EDO06987.1 - 0.0016 18.3 0.6 5.7 7.3 0.0 5.4 4 0 0 4 4 4 2 HEAT repeat Ribosomal_L29 PF00831.18 EDO06988.1 - 6.3e-07 28.9 0.6 9.1e-07 28.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal L29 protein WD40_alt PF14077.1 EDO06988.1 - 0.18 11.4 0.8 0.41 10.3 0.6 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF1786 PF08735.5 EDO06989.1 - 0.12 11.5 0.1 0.18 10.9 0.0 1.3 1 1 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) DUF445 PF04286.7 EDO06990.1 - 0.0026 17.3 0.9 0.0026 17.3 0.6 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF445) IPPT PF01715.12 EDO06991.1 - 4.6e-15 55.3 0.1 7.3e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 IPP transferase Zeta_toxin PF06414.7 EDO06991.1 - 0.0018 17.4 0.0 0.0024 16.9 0.0 1.3 1 1 0 1 1 1 1 Zeta toxin IPT PF01745.11 EDO06991.1 - 0.0054 15.9 0.0 0.0093 15.1 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase KTI12 PF08433.5 EDO06991.1 - 0.011 14.9 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.1 EDO06991.1 - 0.012 15.3 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 EDO06991.1 - 0.019 15.7 0.1 0.041 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EDO06991.1 - 0.033 14.3 0.0 0.049 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDO06991.1 - 0.039 14.2 0.6 0.089 13.0 0.4 1.9 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EDO06991.1 - 0.04 13.3 0.0 0.082 12.3 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF1611 PF07755.6 EDO06991.1 - 0.056 12.0 0.0 0.093 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1611) PhoH PF02562.11 EDO06991.1 - 0.096 11.9 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein IPPT PF01715.12 EDO06992.1 - 1.1e-06 27.9 0.1 1.5e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 IPP transferase NOT2_3_5 PF04153.13 EDO06992.1 - 0.056 13.3 0.1 0.066 13.0 0.1 1.1 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family RRM_1 PF00076.17 EDO06993.1 - 1.9e-07 30.6 0.0 2.5e-05 23.8 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO06993.1 - 0.001 19.0 0.0 0.0034 17.3 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO06993.1 - 0.0014 18.4 0.0 0.0045 16.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4047 PF13256.1 EDO06996.1 - 0.15 11.9 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) VESA1_N PF12785.2 EDO06997.1 - 9e-183 608.4 24.4 9e-183 608.4 16.9 2.4 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 Acyl-CoA_dh_C PF12806.2 EDO06997.1 - 0.16 11.8 0.6 0.58 10.0 0.4 2.0 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Zw10 PF06248.8 EDO06997.1 - 0.19 9.8 0.1 0.95 7.5 0.1 2.0 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 F-box-like_2 PF13013.1 EDO06998.1 - 6e-08 32.3 4.3 0.00044 19.9 0.1 4.2 2 2 2 4 4 4 3 F-box-like domain VESA1_N PF12785.2 EDO06999.1 - 4.2e-213 708.4 18.6 4.2e-213 708.4 12.9 2.2 2 0 0 2 2 1 1 Variant erythrocyte surface antigen-1 Baculo_PEP_C PF04513.7 EDO06999.1 - 0.00097 18.9 1.0 0.01 15.6 0.4 2.7 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 EDO06999.1 - 0.0019 17.7 0.8 0.0039 16.7 0.6 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.7 EDO06999.1 - 0.011 15.5 0.3 2 8.2 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PEP-utilisers_N PF05524.8 EDO06999.1 - 0.058 13.1 1.0 12 5.7 0.4 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Carbpep_Y_N PF05388.6 EDO06999.1 - 0.074 13.2 0.2 0.67 10.1 0.0 2.5 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide ApoLp-III PF07464.6 EDO06999.1 - 0.096 12.7 10.3 1.2 9.1 6.7 2.8 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) WXG100 PF06013.7 EDO06999.1 - 0.11 12.4 1.0 7.7 6.6 0.0 2.9 2 0 0 2 2 2 0 Proteins of 100 residues with WXG AAA_13 PF13166.1 EDO06999.1 - 0.19 10.1 2.8 0.34 9.2 2.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2580 PF10824.3 EDO06999.1 - 0.2 12.0 0.2 0.54 10.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) CK2S PF15011.1 EDO06999.1 - 0.38 10.5 0.9 2.9 7.6 0.3 2.4 2 0 0 2 2 2 0 Casein Kinase 2 substrate DUF4618 PF15397.1 EDO06999.1 - 0.39 10.0 4.3 2.7 7.2 3.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) HisKA_3 PF07730.8 EDO06999.1 - 0.4 11.0 0.6 27 5.2 0.2 2.9 2 0 0 2 2 2 0 Histidine kinase Glutaredoxin2_C PF04399.8 EDO06999.1 - 2.1 7.9 2.8 46 3.6 0.0 3.3 4 0 0 4 4 4 0 Glutaredoxin 2, C terminal domain RRF PF01765.14 EDO06999.1 - 2.1 7.7 8.3 0.099 12.1 0.7 2.3 2 1 1 3 3 3 0 Ribosome recycling factor Myosin_tail_1 PF01576.14 EDO06999.1 - 3.1 5.4 9.3 0.72 7.5 4.0 1.6 2 0 0 2 2 2 0 Myosin tail VESA1_N PF12785.2 EDO07000.1 - 4.1e-224 744.7 21.7 4.1e-224 744.7 15.0 2.4 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 Baculo_PEP_C PF04513.7 EDO07000.1 - 0.021 14.6 6.8 1.8 8.4 0.0 4.0 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SOG2 PF10428.4 EDO07000.1 - 0.094 11.3 0.0 0.17 10.5 0.0 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein ApoLp-III PF07464.6 EDO07000.1 - 0.1 12.6 1.8 0.3 11.1 0.3 2.4 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) ALIX_LYPXL_bnd PF13949.1 EDO07000.1 - 0.4 9.6 0.1 0.77 8.6 0.1 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV PTS_IIA PF02255.11 EDO07000.1 - 0.44 10.4 0.5 28 4.6 0.0 2.3 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF4175 PF13779.1 EDO07000.1 - 6.1 4.4 4.5 26 2.3 3.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4175) F-box-like_2 PF13013.1 EDO07001.1 - 1.3e-06 28.1 0.9 0.1 12.3 0.1 4.2 3 1 0 3 3 3 2 F-box-like domain DUF2770 PF10968.3 EDO07001.1 - 0.072 12.7 1.0 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2770) Band_7 PF01145.20 EDO07001.1 - 0.085 12.7 0.0 7.6 6.4 0.0 2.7 2 2 1 3 3 3 0 SPFH domain / Band 7 family F-box-like_2 PF13013.1 EDO07002.1 - 0.13 12.0 0.2 0.52 10.0 0.1 1.8 1 1 1 2 2 2 0 F-box-like domain EMP24_GP25L PF01105.19 EDO07004.1 - 1.8e-24 86.4 0.5 2.1e-24 86.2 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ribonuc_red_sm PF00268.16 EDO07005.1 - 2.1e-31 108.9 1.5 1e-30 106.6 1.1 1.8 1 1 0 1 1 1 1 Ribonucleotide reductase, small chain DUF3993 PF13158.1 EDO07005.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) Exo_endo_phos PF03372.18 EDO07008.1 - 2.4e-17 63.7 0.0 2.8e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PDEase_I PF00233.14 EDO07010.1 - 3.7e-48 164.3 0.6 3.7e-48 164.3 0.4 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 EDO07010.1 - 0.0017 18.3 0.2 0.008 16.1 0.1 2.1 1 1 1 2 2 2 1 HD domain RRM_1 PF00076.17 EDO07011.1 - 2.2e-25 88.0 0.0 7.9e-16 57.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07011.1 - 6e-16 58.1 0.0 7.2e-11 41.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 EDO07011.1 - 9.4e-08 31.7 4.1 9.4e-08 31.7 2.9 1.8 2 0 0 2 2 2 1 WW domain RRM_5 PF13893.1 EDO07011.1 - 1.3e-07 31.3 0.1 1.9e-06 27.5 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 EDO07011.1 - 0.00023 20.6 0.0 0.00047 19.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Nup35_RRM PF05172.8 EDO07011.1 - 0.0082 15.8 0.0 0.036 13.8 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 EDO07011.1 - 0.033 14.1 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA binding domain Nup35_RRM_2 PF14605.1 EDO07011.1 - 0.037 13.8 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MA3 PF02847.12 EDO07012.1 - 8.8e-21 73.7 1.5 2e-20 72.6 1.1 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.14 EDO07012.1 - 1.8e-19 69.9 0.6 1.8e-19 69.9 0.4 2.8 3 0 0 3 3 3 1 MIF4G domain Ribosomal_S8 PF00410.14 EDO07013.1 - 6.9e-17 61.4 0.0 8.3e-17 61.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 zf-RING_2 PF13639.1 EDO07013.1 - 0.043 13.6 0.0 0.097 12.5 0.0 1.6 2 0 0 2 2 2 0 Ring finger domain Ras PF00071.17 EDO07014.1 - 1.4e-57 193.6 0.5 1.7e-57 193.3 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO07014.1 - 6.1e-17 62.2 0.1 9.2e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO07014.1 - 1.6e-12 47.0 0.1 2e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDO07014.1 - 3.2e-07 30.3 0.3 4.7e-07 29.7 0.2 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDO07014.1 - 0.00013 21.5 0.1 0.0021 17.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EDO07014.1 - 0.00055 19.1 0.0 0.00077 18.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EDO07014.1 - 0.0012 18.0 0.1 0.0015 17.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EDO07014.1 - 0.0059 16.7 0.0 0.022 14.8 0.0 1.9 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 EDO07014.1 - 0.013 14.8 0.1 0.024 13.8 0.0 1.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.1 EDO07014.1 - 0.035 14.0 0.1 0.095 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF2460 PF09343.5 EDO07014.1 - 0.074 12.3 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) Cyclin_N PF00134.18 EDO07015.1 - 1.3e-08 34.4 0.2 3.9e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDO07015.1 - 0.021 14.7 1.3 0.03 14.2 0.1 1.9 2 0 0 2 2 2 0 Cyclin, C-terminal domain Dsh_C PF12316.3 EDO07015.1 - 9.7 6.2 15.6 16 5.5 10.8 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal zf-RING_2 PF13639.1 EDO07017.1 - 1.3e-12 47.3 3.7 1.3e-12 47.3 2.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EDO07017.1 - 1e-09 38.3 2.9 1e-09 38.3 2.0 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDO07017.1 - 6.2e-06 25.7 2.9 6.2e-06 25.7 2.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO07017.1 - 7.4e-06 25.8 12.0 1.3e-05 25.0 1.7 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO07017.1 - 2.3e-05 23.9 11.3 0.00038 20.0 1.7 2.4 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDO07017.1 - 6.9e-05 22.6 2.0 0.00016 21.4 1.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EDO07017.1 - 0.00068 19.5 3.3 0.00068 19.5 2.3 2.0 2 1 0 2 2 2 1 FANCL C-terminal domain zf-RING_5 PF14634.1 EDO07017.1 - 0.0033 17.0 2.4 0.0033 17.0 1.7 2.7 2 1 0 2 2 2 1 zinc-RING finger domain Rad50_zn_hook PF04423.9 EDO07017.1 - 0.017 14.6 1.3 0.074 12.5 0.1 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_3 PF14369.1 EDO07017.1 - 3.6 7.6 11.7 2.5 8.1 3.2 3.8 3 1 0 3 3 3 0 zinc-finger PHD PF00628.24 EDO07017.1 - 3.7 7.3 13.5 1.5 8.5 2.7 3.0 2 1 1 3 3 3 0 PHD-finger zf-P11 PF03854.9 EDO07017.1 - 6.6 6.2 8.3 0.75 9.3 0.4 2.5 2 1 0 2 2 2 0 P-11 zinc finger DUF1253 PF06862.7 EDO07018.1 - 1.8e-135 451.7 4.4 2.4e-135 451.3 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) tRNA-synt_1g PF09334.6 EDO07019.1 - 1.2e-78 264.5 0.2 3.3e-39 134.6 0.0 2.7 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EDO07019.1 - 1.4e-09 36.5 0.1 0.00067 17.7 0.2 4.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EDO07019.1 - 5e-07 29.1 0.3 7.8e-06 25.2 0.1 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Mito_carr PF00153.22 EDO07021.1 - 0.00014 21.5 0.1 0.0039 16.8 0.0 2.5 2 1 0 2 2 2 1 Mitochondrial carrier protein Clp1 PF06807.9 EDO07023.1 - 0.11 12.3 0.1 0.16 11.6 0.0 1.4 1 1 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 DUF4404 PF14357.1 EDO07023.1 - 0.12 12.7 0.7 3.9 7.9 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) RRM_1 PF00076.17 EDO07024.1 - 5.6e-30 102.7 0.6 5.5e-15 54.7 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07024.1 - 3.1e-21 75.1 0.2 1.3e-11 44.3 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07024.1 - 1.1e-14 53.9 0.2 1.2e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDO07024.1 - 1.7e-05 24.6 0.5 0.23 11.3 0.1 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EDO07024.1 - 0.0006 19.5 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mo25 PF08569.6 EDO07025.1 - 0.025 13.6 0.3 0.036 13.1 0.2 1.1 1 0 0 1 1 1 0 Mo25-like FA_desaturase_2 PF03405.9 EDO07026.1 - 0.00028 19.7 0.1 0.00036 19.4 0.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DnaJ PF00226.26 EDO07027.1 - 4.1e-16 58.4 0.4 4.1e-16 58.4 0.3 1.9 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 EDO07027.1 - 2e-09 37.3 1.9 7.7e-09 35.4 0.2 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDO07027.1 - 6.9e-09 35.6 0.7 6.9e-09 35.6 0.5 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EDO07027.1 - 0.00015 21.8 0.2 0.00057 20.0 0.2 2.1 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO07027.1 - 0.00015 21.9 0.4 0.00059 20.0 0.3 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EDO07027.1 - 0.0085 15.9 0.6 0.35 10.8 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EDO07027.1 - 0.022 14.8 5.3 0.022 14.8 3.7 3.2 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) CHORD PF04968.7 EDO07027.1 - 0.028 14.6 0.6 0.11 12.7 0.4 2.1 1 0 0 1 1 1 0 CHORD zf-DBF PF07535.7 EDO07027.1 - 0.037 13.7 0.6 0.037 13.7 0.4 2.2 2 0 0 2 2 2 0 DBF zinc finger DUF848 PF05852.6 EDO07027.1 - 0.11 12.3 7.4 0.23 11.3 5.1 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4239 PF14023.1 EDO07027.1 - 0.37 10.1 3.2 0.62 9.3 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Transpos_assoc PF13963.1 EDO07027.1 - 0.46 10.5 7.0 1.8 8.5 0.4 3.2 2 1 0 3 3 3 0 Transposase-associated domain Peptidase_C97 PF05903.9 EDO07028.1 - 1.4e-30 106.0 0.3 9.4e-30 103.3 0.0 2.0 2 0 0 2 2 2 1 PPPDE putative peptidase domain DUF3858 PF12970.2 EDO07028.1 - 0.032 14.0 1.4 17 5.2 0.0 3.3 2 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3858) LRAT PF04970.8 EDO07028.1 - 0.035 14.0 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 Lecithin retinol acyltransferase RRM_1 PF00076.17 EDO07029.1 - 7.5e-37 124.8 0.0 5.1e-19 67.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07029.1 - 2.1e-26 91.6 0.0 4e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07029.1 - 1.4e-12 47.2 0.0 9.9e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDO07029.1 - 0.079 12.8 0.0 8.8 6.2 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif RHSP PF07999.6 EDO07029.1 - 0.11 11.0 0.1 0.79 8.2 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon hot spot protein DUF2256 PF10013.4 EDO07029.1 - 0.12 12.1 2.7 5.9 6.7 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Myb_DNA-bind_5 PF13873.1 EDO07029.1 - 0.32 10.9 2.1 16 5.5 0.3 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Phosducin PF02114.11 EDO07030.1 - 3.9e-07 29.0 0.4 4.9e-07 28.7 0.3 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EDO07030.1 - 4e-07 29.6 0.3 1.5e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin RNA_lig_T4_1 PF09511.5 EDO07030.1 - 0.051 13.0 0.6 0.078 12.4 0.4 1.3 1 0 0 1 1 1 0 RNA ligase Radial_spoke_3 PF06098.6 EDO07030.1 - 0.068 12.1 4.0 0.092 11.7 2.7 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 DUF4376 PF14301.1 EDO07030.1 - 0.073 13.2 0.3 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) BLOC1_2 PF10046.4 EDO07030.1 - 0.12 12.5 1.5 0.2 11.7 1.0 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Auto_anti-p27 PF06677.7 EDO07031.1 - 4e-08 32.8 1.9 6.9e-08 32.1 1.3 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribosomal_L37ae PF01780.14 EDO07031.1 - 0.0091 15.8 0.3 0.015 15.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 EDO07031.1 - 0.11 12.0 1.8 0.25 10.8 1.2 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain Peptidase_M24 PF00557.19 EDO07032.1 - 4.5e-46 157.0 0.0 5.5e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EDO07032.1 - 0.28 11.0 7.8 0.81 9.6 5.4 1.7 1 0 0 1 1 1 0 MYND finger BIR PF00653.16 EDO07033.1 - 0.011 16.0 0.2 0.038 14.4 0.0 1.9 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain NTP_transf_2 PF01909.18 EDO07034.1 - 2.7e-06 27.5 0.0 6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 EDO07034.1 - 0.00029 19.7 0.0 0.63 8.7 0.0 2.4 2 0 0 2 2 2 2 Poly(A) polymerase central domain PAP_assoc PF03828.14 EDO07034.1 - 0.26 11.2 3.0 1.1 9.2 1.4 2.5 2 1 0 2 2 2 0 Cid1 family poly A polymerase Cpn60_TCP1 PF00118.19 EDO07035.1 - 8.6e-121 403.9 6.6 9.9e-121 403.7 4.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_S5 PF00333.15 EDO07037.1 - 2e-08 33.8 0.1 4e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EDO07037.1 - 3.7e-06 26.1 0.0 9.8e-06 24.7 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF3249 PF11615.3 EDO07039.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3249) Histone PF00125.19 EDO07040.1 - 1e-18 67.1 0.3 1.5e-18 66.6 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 EDO07040.1 - 0.0029 17.8 0.4 0.0044 17.2 0.0 1.4 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EDO07040.1 - 0.0075 16.3 0.1 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RRM_1 PF00076.17 EDO07041.1 - 2.1e-20 72.1 0.0 2.8e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07041.1 - 6.2e-15 54.9 0.0 8.7e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07041.1 - 2.4e-12 46.5 0.0 3.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 EDO07041.1 - 0.026 14.0 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) RRM_3 PF08777.6 EDO07041.1 - 0.058 13.2 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif DUF1777 PF08648.7 EDO07041.1 - 0.16 11.6 24.5 0.5 10.0 17.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Corona_nucleoca PF00937.13 EDO07041.1 - 9.9 4.9 12.2 12 4.7 8.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Skp1 PF01466.14 EDO07042.1 - 1.3e-34 118.0 1.6 1.9e-34 117.4 1.1 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EDO07042.1 - 3.3e-13 49.5 0.0 6.5e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DUF2101 PF09874.4 EDO07043.1 - 0.37 10.2 2.7 0.16 11.4 0.3 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) Ribosomal_L24e PF01246.15 EDO07044.1 - 1.5e-29 101.6 2.2 4.7e-29 100.0 1.5 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 EDO07044.1 - 0.0043 16.6 2.7 0.0083 15.7 1.7 1.7 1 1 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif DUF4478 PF14793.1 EDO07044.1 - 0.053 13.1 0.2 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) RNase_H2-Ydr279 PF09468.5 EDO07044.1 - 0.53 9.4 10.6 0.76 8.9 7.3 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SYF2 PF08231.7 EDO07045.1 - 3.8e-41 140.7 13.3 5.5e-41 140.2 9.2 1.2 1 0 0 1 1 1 1 SYF2 splicing factor Pro_isomerase PF00160.16 EDO07045.1 - 5.7e-25 88.3 0.1 1.2e-24 87.2 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD IMPDH PF00478.20 EDO07046.1 - 2.9e-126 421.1 3.2 3.6e-126 420.8 2.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EDO07046.1 - 2.3e-15 56.2 0.9 1.1e-13 50.8 0.3 2.7 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EDO07046.1 - 4.7e-15 55.5 0.9 2.1e-07 30.3 0.3 3.1 3 0 0 3 3 3 2 Nitronate monooxygenase CBS PF00571.23 EDO07046.1 - 5.8e-14 51.6 0.1 2.1e-07 30.5 0.0 2.7 2 0 0 2 2 2 2 CBS domain His_biosynth PF00977.16 EDO07046.1 - 1.1e-05 24.7 0.4 0.067 12.4 0.0 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein Glu_synthase PF01645.12 EDO07046.1 - 4.9e-05 22.4 1.3 4.9e-05 22.4 0.9 1.8 1 1 1 2 2 2 1 Conserved region in glutamate synthase NanE PF04131.9 EDO07046.1 - 5.1e-05 22.3 1.1 0.0018 17.3 0.6 3.3 1 1 1 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.16 EDO07046.1 - 0.00019 20.5 4.1 0.0012 17.8 0.5 2.5 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.9 EDO07046.1 - 0.0018 17.4 5.0 0.0038 16.3 1.1 2.6 2 1 1 3 3 3 1 Thiazole biosynthesis protein ThiG Response_reg PF00072.19 EDO07046.1 - 0.015 15.2 0.1 0.16 12.0 0.0 2.4 2 0 0 2 2 2 0 Response regulator receiver domain PcrB PF01884.12 EDO07046.1 - 0.022 13.9 4.9 1.4 8.0 0.0 3.4 2 1 1 3 3 3 0 PcrB family B12-binding PF02310.14 EDO07046.1 - 0.039 13.8 0.3 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain QRPTase_C PF01729.14 EDO07046.1 - 0.046 13.2 0.0 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Aldolase PF01081.14 EDO07046.1 - 0.28 10.3 2.2 1.4 7.9 0.1 2.6 3 0 0 3 3 3 0 KDPG and KHG aldolase DEAD PF00270.24 EDO07047.1 - 9.8e-31 106.5 0.2 2.6e-30 105.1 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO07047.1 - 7.9e-20 70.5 0.0 1.7e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO07047.1 - 2.8e-10 40.3 0.0 5.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EDO07047.1 - 0.0026 16.2 0.0 0.41 9.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_22 PF13401.1 EDO07047.1 - 0.0069 16.5 0.1 0.031 14.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 EDO07047.1 - 0.0073 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein T4SS-DNA_transf PF02534.9 EDO07047.1 - 0.066 11.7 0.0 0.19 10.2 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Helicase_C_2 PF13307.1 EDO07047.1 - 0.066 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain WD40 PF00400.27 EDO07048.1 - 2.2e-31 106.5 14.3 2.9e-07 30.0 0.1 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat Prp19 PF08606.6 EDO07048.1 - 3.9e-31 106.5 0.9 1.1e-30 105.1 0.6 1.8 1 1 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 EDO07048.1 - 1.7e-07 31.0 0.0 3.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain DUF3312 PF11768.3 EDO07048.1 - 4.1e-06 25.3 0.0 0.12 10.6 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF3312) zf-Nse PF11789.3 EDO07048.1 - 0.0014 18.0 0.6 0.032 13.7 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit eIF2A PF08662.6 EDO07048.1 - 0.0072 16.0 0.0 3.5 7.3 0.0 3.8 1 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EDO07048.1 - 0.026 12.7 1.8 0.056 11.5 0.8 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Rtf2 PF04641.7 EDO07048.1 - 0.028 13.6 0.1 0.053 12.7 0.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Matrilin_ccoil PF10393.4 EDO07050.1 - 0.00071 18.8 0.2 0.17 11.2 0.0 2.2 2 0 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin PspB PF06667.7 EDO07050.1 - 0.0016 18.3 1.7 0.023 14.5 0.0 2.2 2 0 0 2 2 2 1 Phage shock protein B FlgN PF05130.7 EDO07050.1 - 0.0035 17.5 0.4 0.0043 17.3 0.3 1.1 1 0 0 1 1 1 1 FlgN protein Mnd1 PF03962.10 EDO07050.1 - 0.0037 16.9 0.5 0.0048 16.5 0.3 1.1 1 0 0 1 1 1 1 Mnd1 family HalX PF08663.5 EDO07050.1 - 0.01 15.7 0.2 0.15 12.0 0.0 2.4 2 1 0 2 2 2 0 HalX domain Rootletin PF15035.1 EDO07050.1 - 0.015 15.2 1.6 0.021 14.7 1.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion BLOC1_2 PF10046.4 EDO07050.1 - 0.025 14.7 0.7 1.8 8.7 0.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PspA_IM30 PF04012.7 EDO07050.1 - 0.036 13.4 0.1 0.5 9.6 0.0 2.0 2 0 0 2 2 2 0 PspA/IM30 family Gp-FAR-1 PF05823.7 EDO07050.1 - 0.041 13.8 0.2 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Syntaxin PF00804.20 EDO07050.1 - 0.059 13.5 1.3 0.1 12.7 0.9 1.4 1 1 0 1 1 1 0 Syntaxin DUF4559 PF15112.1 EDO07050.1 - 0.065 12.3 0.7 0.085 12.0 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) AKNA PF12443.3 EDO07050.1 - 0.068 13.1 0.2 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF1664 PF07889.7 EDO07050.1 - 0.076 12.8 0.2 3.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.10 EDO07050.1 - 0.09 12.2 1.9 2.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator Lebercilin PF15619.1 EDO07050.1 - 0.11 11.8 3.8 2.8 7.2 0.2 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4140 PF13600.1 EDO07050.1 - 0.12 12.8 0.1 9.7 6.7 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3037 PF11236.3 EDO07050.1 - 0.13 12.3 0.1 0.34 10.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3037) Ada3 PF10198.4 EDO07050.1 - 0.15 11.8 1.1 0.24 11.1 0.2 1.7 1 1 1 2 2 2 0 Histone acetyltransferases subunit 3 Spectrin PF00435.16 EDO07050.1 - 0.26 11.5 2.5 0.83 9.9 1.2 2.0 1 1 1 2 2 2 0 Spectrin repeat CENP-Q PF13094.1 EDO07050.1 - 0.32 11.0 3.0 0.43 10.6 2.1 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SF-assemblin PF06705.6 EDO07050.1 - 0.41 9.7 3.1 9.8 5.2 0.3 2.0 1 1 0 2 2 2 0 SF-assemblin/beta giardin DUF4200 PF13863.1 EDO07050.1 - 0.44 10.4 3.7 11 5.9 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) IncA PF04156.9 EDO07050.1 - 0.75 9.3 3.8 2.9 7.4 0.4 2.0 1 1 1 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 EDO07050.1 - 0.99 9.1 5.1 2.6 7.7 0.9 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EDO07050.1 - 2 8.3 6.1 15 5.4 2.9 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding SF3b1 PF08920.5 EDO07051.1 - 3.6e-32 111.4 2.1 8e-32 110.2 1.5 1.6 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT PF02985.17 EDO07051.1 - 1.6e-14 52.6 3.9 0.063 13.3 0.1 9.5 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.1 EDO07051.1 - 4.5e-14 52.4 4.0 0.0023 18.1 0.0 7.7 4 2 3 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 EDO07051.1 - 1.7e-12 47.4 2.0 0.054 13.9 0.0 8.2 7 2 3 10 10 10 3 HEAT-like repeat Adaptin_N PF01602.15 EDO07051.1 - 4.1e-06 25.4 2.7 0.00016 20.1 0.0 3.1 3 0 0 3 3 3 1 Adaptin N terminal region Arm PF00514.18 EDO07051.1 - 0.00029 20.5 5.6 0.64 9.9 0.3 5.4 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EDO07051.1 - 0.005 16.2 0.3 1.1 8.5 0.0 3.4 4 0 0 4 4 4 1 CLASP N terminal DUF2363 PF10155.4 EDO07051.1 - 0.016 15.0 0.4 1.8 8.5 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) Vac14_Fab1_bd PF12755.2 EDO07051.1 - 0.085 13.2 0.2 21 5.5 0.0 3.8 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region DUF457 PF04307.9 EDO07051.1 - 0.19 11.0 0.8 0.41 9.9 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Dopey_N PF04118.9 EDO07051.1 - 0.23 10.2 1.0 9.9 4.8 0.1 2.9 3 0 0 3 3 3 0 Dopey, N-terminal Cpn60_TCP1 PF00118.19 EDO07053.1 - 7.7e-147 489.8 9.4 8.9e-147 489.6 6.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ATP-synt_10 PF05176.9 EDO07054.1 - 0.072 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP10 protein DUF572 PF04502.8 EDO07055.1 - 8.1e-30 104.1 4.4 2.3e-28 99.3 0.4 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF572) Tox-REase-7 PF15649.1 EDO07055.1 - 0.3 11.2 2.1 0.93 9.6 0.3 2.2 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 7 Cpn60_TCP1 PF00118.19 EDO07057.1 - 3.8e-104 349.0 4.3 5.1e-104 348.5 3.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PAP_assoc PF03828.14 EDO07059.1 - 0.096 12.6 0.4 0.46 10.4 0.1 2.3 3 0 0 3 3 3 0 Cid1 family poly A polymerase Thioredoxin PF00085.15 EDO07060.1 - 0.0017 17.9 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin WD40 PF00400.27 EDO07061.1 - 5.1e-31 105.4 6.1 3.6e-08 32.9 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EDO07061.1 - 0.00025 20.8 1.6 10 5.7 0.0 5.1 4 1 1 5 5 5 2 Transcription factor IIIC subunit delta N-term eIF2A PF08662.6 EDO07061.1 - 0.0013 18.4 0.0 3.9 7.1 0.0 4.0 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EDO07061.1 - 0.0016 17.9 0.0 0.009 15.4 0.0 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EDO07061.1 - 0.042 12.6 0.0 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region PD40 PF07676.7 EDO07061.1 - 0.045 13.4 2.7 53 3.6 0.1 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF902 PF06001.8 EDO07061.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) DNA_pol_B PF00136.16 EDO07062.1 - 2.2e-100 336.6 3.8 6.7e-100 335.0 0.5 2.7 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EDO07062.1 - 4.2e-22 78.4 4.0 7e-22 77.7 2.8 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EDO07062.1 - 4.5e-14 52.0 12.0 1.1e-13 50.7 8.3 1.7 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal RRM_6 PF14259.1 EDO07063.1 - 2e-20 72.4 0.0 1.1e-15 57.3 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO07063.1 - 3.9e-12 45.6 0.1 0.0019 17.7 0.0 5.3 3 2 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07063.1 - 4.9e-11 42.3 0.1 0.0007 19.3 0.0 3.4 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosom_S12_S23 PF00164.20 EDO07064.1 - 2e-37 127.3 1.1 4.6e-37 126.1 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein S12/S23 EMP24_GP25L PF01105.19 EDO07065.1 - 6.1e-37 127.1 3.3 7e-37 126.9 2.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3899 PF13038.1 EDO07065.1 - 0.012 15.7 0.2 6.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF2098 PF09871.4 EDO07065.1 - 0.038 13.9 1.0 0.094 12.6 0.6 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Filamin PF00630.14 EDO07065.1 - 0.064 13.8 0.6 0.3 11.6 0.1 2.0 2 0 0 2 2 2 0 Filamin/ABP280 repeat MCM PF00493.18 EDO07066.1 - 6.5e-107 357.1 0.1 1.7e-106 355.7 0.1 1.7 1 1 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDO07066.1 - 3.8e-09 37.0 0.0 1.3e-08 35.3 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDO07066.1 - 9.3e-09 34.7 0.1 0.00044 19.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDO07066.1 - 2.6e-07 30.4 0.0 1.6e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDO07066.1 - 1.1e-05 25.1 0.0 4.1e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EDO07066.1 - 9.9e-05 22.5 0.0 0.0014 18.7 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDO07066.1 - 0.0041 16.6 0.0 3.9 6.9 0.0 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_22 PF13401.1 EDO07066.1 - 0.04 14.0 0.0 0.4 10.8 0.0 2.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EDO07066.1 - 0.092 12.7 0.7 0.8 9.6 0.1 2.8 3 0 0 3 3 3 0 AAA ATPase domain UQ_con PF00179.21 EDO07067.1 - 1.3e-44 151.0 0.0 1.5e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO07067.1 - 0.001 18.8 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EDO07067.1 - 0.0033 17.1 0.1 0.0059 16.2 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EDO07067.1 - 0.0062 16.4 0.1 0.0076 16.1 0.1 1.5 1 1 0 1 1 1 1 RWD domain DUF1411 PF07199.6 EDO07069.1 - 0.019 14.4 0.1 0.089 12.2 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1411) DUF1411 PF07199.6 EDO07070.1 - 6.7e-05 22.4 0.1 0.00015 21.2 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1411) Nop14 PF04147.7 EDO07071.1 - 3.2 5.5 6.6 4 5.2 4.6 1.1 1 0 0 1 1 1 0 Nop14-like family PHD PF00628.24 EDO07072.1 - 0.0012 18.4 5.8 0.032 13.9 4.0 3.0 1 1 0 1 1 1 1 PHD-finger OST-HTH PF12872.2 EDO07073.1 - 0.017 14.9 0.1 0.077 12.8 0.0 2.1 2 0 0 2 2 2 0 OST-HTH/LOTUS domain zf-RING_2 PF13639.1 EDO07074.1 - 3e-09 36.5 8.5 3e-09 36.5 5.9 3.0 2 1 0 2 2 1 1 Ring finger domain PHD PF00628.24 EDO07074.1 - 2e-08 33.8 10.2 2e-08 33.8 7.1 2.6 2 1 0 2 2 1 1 PHD-finger zf-C3HC4_3 PF13920.1 EDO07074.1 - 2.4e-08 33.4 5.7 2.4e-08 33.4 4.0 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO07074.1 - 1.1e-07 31.3 9.2 1.1e-07 31.3 6.4 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO07074.1 - 3.1e-06 27.1 10.8 3.1e-06 27.1 7.5 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDO07074.1 - 3.7e-06 26.9 4.0 3.7e-06 26.9 2.8 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EDO07074.1 - 9e-06 25.3 8.0 9e-06 25.3 5.6 2.8 3 1 0 3 3 2 1 zinc-RING finger domain zf-RING_3 PF14369.1 EDO07074.1 - 0.0004 20.3 3.4 0.00046 20.1 0.6 2.6 2 0 0 2 2 2 1 zinc-finger Baculo_IE-1 PF05290.6 EDO07074.1 - 0.0016 18.2 1.3 0.0031 17.2 0.9 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 EDO07074.1 - 0.021 14.4 6.8 0.058 12.9 4.7 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EDO07074.1 - 0.11 12.1 8.6 0.032 13.9 1.2 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EDO07074.1 - 0.58 10.0 11.2 0.65 9.9 5.2 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EDO07074.1 - 1.1 9.1 13.3 0.12 12.1 0.5 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD_2 PF13831.1 EDO07074.1 - 7 6.0 16.2 0.021 14.1 2.9 2.5 2 0 0 2 2 2 0 PHD-finger Pyr_redox_2 PF07992.9 EDO07075.1 - 1.4e-39 136.0 13.7 1.1e-38 133.1 9.5 3.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EDO07075.1 - 4.8e-33 113.4 0.3 1.4e-32 111.9 0.1 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EDO07075.1 - 2.9e-23 82.0 6.2 1.1e-18 67.4 0.9 3.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO07075.1 - 1.7e-11 44.5 0.4 1.1e-09 38.6 0.3 2.5 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDO07075.1 - 4.4e-11 42.2 11.8 0.00028 19.9 0.1 4.1 3 1 1 4 4 4 3 FAD dependent oxidoreductase GIDA PF01134.17 EDO07075.1 - 7e-10 38.3 8.1 7.3e-06 25.0 0.5 3.1 3 0 0 3 3 3 3 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EDO07075.1 - 8.8e-10 38.4 1.5 1.8e-05 24.6 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EDO07075.1 - 6.8e-09 35.3 6.5 5e-08 32.4 0.1 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EDO07075.1 - 2e-08 33.1 12.6 0.0002 19.9 0.2 4.5 2 2 2 5 5 5 2 HI0933-like protein Thi4 PF01946.12 EDO07075.1 - 1.7e-07 30.5 3.4 6.9e-05 22.0 0.2 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 EDO07075.1 - 1.4e-06 27.4 7.1 7.7e-05 21.7 0.3 2.8 2 1 1 3 3 3 2 FAD binding domain FAD_binding_3 PF01494.14 EDO07075.1 - 2.9e-06 26.5 2.2 0.012 14.7 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.13 EDO07075.1 - 5.3e-06 26.2 2.6 0.0009 18.9 0.1 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EDO07075.1 - 6.8e-06 25.2 1.6 0.029 13.3 0.1 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_7 PF13241.1 EDO07075.1 - 0.00026 21.1 1.0 0.051 13.8 0.2 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding XdhC_C PF13478.1 EDO07075.1 - 0.0012 19.1 0.0 0.25 11.6 0.0 2.4 2 0 0 2 2 2 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 EDO07075.1 - 0.0021 17.2 0.7 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EDO07075.1 - 0.0048 16.4 0.3 0.043 13.3 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EDO07075.1 - 0.012 15.3 0.8 0.16 11.6 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EDO07075.1 - 0.022 14.1 3.9 0.48 9.7 0.3 2.6 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EDO07075.1 - 0.057 13.4 0.9 0.58 10.1 0.1 2.8 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 EDO07075.1 - 1.7 8.3 5.0 1.9 8.2 0.0 3.0 4 0 0 4 4 4 0 FAD-NAD(P)-binding Ribosomal_L27 PF01016.14 EDO07076.1 - 6.2e-29 99.6 1.2 8.1e-29 99.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein DUF342 PF03961.8 EDO07076.1 - 0.097 11.0 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FAD_binding_2 PF00890.19 EDO07077.1 - 5.6e-124 414.1 1.8 6.1e-124 414.0 0.6 1.5 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.15 EDO07077.1 - 7.2e-47 158.4 0.4 1.1e-46 157.8 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EDO07077.1 - 1.3e-06 28.4 0.1 0.00016 21.5 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDO07077.1 - 9.2e-06 24.7 0.1 0.00028 19.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EDO07077.1 - 7.4e-05 21.7 0.4 0.026 13.3 0.7 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.12 EDO07077.1 - 8.3e-05 21.7 0.4 0.017 14.2 0.1 2.5 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 EDO07077.1 - 0.00055 19.1 0.2 0.00092 18.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EDO07077.1 - 0.039 12.4 0.5 0.16 10.3 0.2 2.1 3 0 0 3 3 3 0 HI0933-like protein RTC PF01137.16 EDO07079.1 - 2.2e-14 52.7 0.0 2.7e-13 49.2 0.0 2.0 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EDO07079.1 - 2.1e-06 27.6 0.1 2.1e-05 24.4 0.1 2.2 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain tRNA-synt_2b PF00587.20 EDO07080.1 - 4e-32 111.1 0.1 1.1e-31 109.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EDO07080.1 - 9.4e-14 51.3 2.3 3.2e-13 49.6 1.6 1.9 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Tubulin PF00091.20 EDO07081.1 - 4.4e-75 252.2 0.0 9.5e-75 251.1 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDO07081.1 - 1e-47 161.3 0.4 1.7e-47 160.5 0.3 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EDO07081.1 - 3.4e-06 27.1 0.0 7.6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 EDO07081.1 - 0.017 14.1 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Tubulin like DUF900 PF05990.7 EDO07083.1 - 6.5e-06 25.6 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) MCM PF00493.18 EDO07084.1 - 1.4e-123 411.9 0.1 2e-123 411.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDO07084.1 - 1.4e-13 51.3 2.5 4.8e-12 46.4 0.1 2.8 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDO07084.1 - 6.6e-07 28.6 1.1 4.4e-05 22.7 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EDO07084.1 - 8.3e-06 25.4 0.0 2.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO07084.1 - 0.00059 19.5 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NUC194 PF08163.7 EDO07084.1 - 0.023 13.5 1.0 0.04 12.7 0.7 1.3 1 0 0 1 1 1 0 NUC194 domain AAA_8 PF12780.2 EDO07084.1 - 0.079 11.9 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 DivIC PF04977.10 EDO07084.1 - 2.9 7.4 6.3 19 4.8 0.1 3.3 4 0 0 4 4 4 0 Septum formation initiator FH2 PF02181.18 EDO07085.1 - 2.7e-42 144.9 5.3 3.7e-42 144.5 3.6 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain PTEN_C2 PF10409.4 EDO07085.1 - 8.6e-06 25.5 0.0 5.8e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein polyprenyl_synt PF00348.12 EDO07087.1 - 9e-35 119.7 0.2 1.7e-34 118.8 0.2 1.4 1 1 0 1 1 1 1 Polyprenyl synthetase Sigma70_r1_2 PF00140.15 EDO07088.1 - 0.06 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Vac14_Fab1_bd PF12755.2 EDO07089.1 - 0.02 15.2 0.9 4.2 7.8 0.1 3.1 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Exotox-A_target PF09102.5 EDO07089.1 - 0.083 12.3 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Exotoxin A, targeting DUF445 PF04286.7 EDO07089.1 - 0.28 10.6 3.9 1 8.8 1.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF445) TaqI_C PF12950.2 EDO07090.1 - 0.086 12.6 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 TaqI-like C-terminal specificity domain zf-HIT PF04438.11 EDO07091.1 - 0.00036 20.1 13.3 0.00036 20.1 9.2 1.8 2 0 0 2 2 2 1 HIT zinc finger Guanylate_cyc PF00211.15 EDO07092.1 - 8.3e-16 57.8 0.0 6.7e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain SDA1 PF05285.7 EDO07093.1 - 2 7.5 24.2 4.5 6.4 16.8 1.5 1 0 0 1 1 1 0 SDA1 Mannosyl_trans2 PF04188.8 EDO07094.1 - 1e-20 74.1 27.7 4.3e-12 45.6 14.6 3.1 2 1 0 2 2 2 2 Mannosyltransferase (PIG-V)) DUF3329 PF11808.3 EDO07094.1 - 0.54 10.3 3.9 0.39 10.8 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) s48_45 PF07422.8 EDO07095.1 - 0.00087 19.3 11.8 0.22 11.6 1.1 4.0 3 1 0 3 3 3 3 Sexual stage antigen s48/45 domain MIF4G PF02854.14 EDO07096.1 - 3.3e-27 95.2 0.7 4e-27 94.9 0.5 1.1 1 0 0 1 1 1 1 MIF4G domain CBM_X2 PF03442.9 EDO07096.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain X2 tRNA_anti-codon PF01336.20 EDO07098.1 - 0.02 14.7 0.1 0.04 13.7 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Ribosomal_L2_C PF03947.13 EDO07101.1 - 6.6e-46 155.3 0.3 9.5e-46 154.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EDO07101.1 - 3.7e-28 97.2 0.1 1.2e-27 95.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain WD40 PF00400.27 EDO07103.1 - 1.9e-07 30.7 4.5 0.59 10.1 0.0 6.1 7 0 0 7 7 7 2 WD domain, G-beta repeat PQQ PF01011.16 EDO07103.1 - 0.00028 20.2 0.1 0.047 13.2 0.0 3.1 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_3 PF13570.1 EDO07103.1 - 0.017 15.3 0.1 3.6 7.9 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain PQQ_2 PF13360.1 EDO07103.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 PQQ-like domain CSD PF00313.17 EDO07103.1 - 0.069 12.9 0.2 1.2 8.9 0.0 2.7 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain s48_45 PF07422.8 EDO07104.1 - 1.4e-06 28.3 4.4 0.0017 18.4 0.0 4.3 5 0 0 5 5 5 2 Sexual stage antigen s48/45 domain PRP38 PF03371.10 EDO07105.1 - 1.1e-62 210.6 0.1 1.3e-62 210.4 0.1 1.0 1 0 0 1 1 1 1 PRP38 family CKS PF01111.14 EDO07106.1 - 2.2e-17 62.6 0.3 5.3e-17 61.4 0.2 1.7 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit S1-P1_nuclease PF02265.11 EDO07108.1 - 1.6e-08 34.5 0.0 0.00021 21.0 0.0 2.2 2 0 0 2 2 2 2 S1/P1 Nuclease RabGAP-TBC PF00566.13 EDO07109.1 - 5.7e-50 169.7 0.9 7.8e-50 169.3 0.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Qn_am_d_aIV PF09100.5 EDO07109.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV ATP_bind_3 PF01171.15 EDO07110.1 - 3.2e-08 33.2 0.0 5.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 PP-loop family ATP_bind_3 PF01171.15 EDO07111.1 - 3.3e-15 56.0 2.0 1.9e-05 24.2 0.0 3.1 3 0 0 3 3 3 3 PP-loop family Adeno_E4_ORF3 PF06931.6 EDO07111.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Mastadenovirus E4 ORF3 protein AP_endonuc_2 PF01261.19 EDO07111.1 - 0.097 11.9 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Acatn PF13000.2 EDO07112.1 - 1.4e-49 169.0 14.9 4.1e-37 127.9 5.1 3.8 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MFS_1 PF07690.11 EDO07112.1 - 0.00043 19.0 9.7 0.02 13.6 1.2 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily NTF2 PF02136.15 EDO07113.1 - 1.1e-10 41.8 0.1 9.7e-10 38.8 0.1 2.2 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_6 PF14259.1 EDO07113.1 - 0.084 12.8 0.1 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cons_hypoth95 PF03602.10 EDO07115.1 - 1.3e-27 96.3 0.0 1.7e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EDO07115.1 - 9.7e-11 41.7 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO07115.1 - 1.9e-08 34.0 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO07115.1 - 1.5e-06 28.7 0.0 2.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EDO07115.1 - 5.3e-06 26.0 0.1 7.7e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EDO07115.1 - 2e-05 24.0 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EDO07115.1 - 0.00027 21.2 0.0 0.00038 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EDO07115.1 - 0.0048 16.4 0.0 0.0074 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MethyltransfD12 PF02086.10 EDO07115.1 - 0.013 14.9 0.2 0.036 13.5 0.0 1.6 1 1 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.8 EDO07115.1 - 0.024 13.7 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF445 PF04286.7 EDO07117.1 - 0.073 12.5 4.9 0.25 10.8 2.4 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF445) DUF2856 PF11043.3 EDO07117.1 - 0.086 12.9 0.5 0.38 10.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) GRASP55_65 PF04495.9 EDO07118.1 - 5.8e-53 178.5 0.1 2.8e-44 150.4 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EDO07118.1 - 7.7e-08 32.1 0.0 0.0028 17.5 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.19 EDO07118.1 - 0.038 14.1 0.0 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) ECH PF00378.15 EDO07119.1 - 0.00035 19.7 0.0 0.00089 18.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DEAD PF00270.24 EDO07120.1 - 5.9e-16 58.4 0.0 2.7e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO07120.1 - 1.1e-10 41.2 0.0 2.1e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO07120.1 - 0.025 14.3 0.0 0.39 10.5 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TBP PF00352.16 EDO07121.1 - 6.1e-11 41.5 0.2 0.00014 21.1 0.0 3.1 3 0 0 3 3 3 2 Transcription factor TFIID (or TATA-binding protein, TBP) LAT PF15234.1 EDO07121.1 - 0.098 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells ATP_bind_1 PF03029.12 EDO07123.1 - 1.2e-57 195.1 0.0 2.7e-51 174.4 0.1 3.0 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EDO07123.1 - 6.8e-07 30.1 0.0 1.4e-06 29.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO07123.1 - 3.9e-05 23.9 0.0 0.00011 22.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EDO07123.1 - 0.0001 22.2 0.1 0.00027 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EDO07123.1 - 0.00062 19.3 0.0 0.00089 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EDO07123.1 - 0.0021 17.7 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EDO07123.1 - 0.0078 16.1 0.0 0.071 13.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EDO07123.1 - 0.0079 16.3 0.1 0.015 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 EDO07123.1 - 0.01 15.2 0.0 0.034 13.5 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain KTI12 PF08433.5 EDO07123.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EDO07123.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EDO07123.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 EDO07123.1 - 0.024 14.5 0.0 0.071 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EDO07123.1 - 0.024 14.8 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EDO07123.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EDO07123.1 - 0.031 14.0 0.0 0.057 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO07123.1 - 0.033 14.1 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 EDO07123.1 - 0.035 13.2 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 EDO07123.1 - 0.037 13.4 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 EDO07123.1 - 0.069 12.6 0.0 0.3 10.5 0.0 1.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ArsA_ATPase PF02374.10 EDO07123.1 - 0.075 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_29 PF13555.1 EDO07123.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EDO07123.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter PRK PF00485.13 EDO07123.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PhoH PF02562.11 EDO07123.1 - 0.17 11.1 0.0 1.9 7.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein ATP-synt_Eps PF04627.8 EDO07125.1 - 9.5e-05 21.8 0.1 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain GTP_EFTU PF00009.22 EDO07126.1 - 2e-43 148.0 0.0 5.1e-43 146.7 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EDO07126.1 - 3.7e-07 29.9 0.0 1.2e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 EDO07126.1 - 6.7e-06 25.8 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EDO07126.1 - 0.00027 20.8 0.0 0.00064 19.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDO07126.1 - 0.00056 20.3 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EDO07126.1 - 0.002 17.3 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 EDO07126.1 - 0.0029 16.6 0.1 0.01 14.8 0.0 1.8 2 0 0 2 2 2 1 Septin GTP_EFTU_D2 PF03144.20 EDO07126.1 - 0.013 15.6 1.3 0.077 13.1 0.9 2.2 1 1 0 1 1 1 0 Elongation factor Tu domain 2 FeoB_N PF02421.13 EDO07126.1 - 0.022 14.0 0.0 0.089 12.0 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B F_bP_aldolase PF01116.15 EDO07126.1 - 0.027 13.5 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Peptidase_C1 PF00112.18 EDO07127.1 - 2.3e-62 210.7 1.4 2.3e-62 210.7 1.0 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EDO07127.1 - 4e-08 33.3 5.2 7.9e-08 32.4 3.6 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EDO07127.1 - 1e-06 27.6 0.9 0.00011 20.9 0.0 2.4 2 1 0 2 2 2 2 Peptidase C1-like family RNase_E_G PF10150.4 EDO07129.1 - 0.0082 15.4 4.5 0.4 9.8 0.1 2.5 2 1 0 3 3 3 2 Ribonuclease E/G family KH_dom-like PF14714.1 EDO07130.1 - 1.1e-21 76.5 0.0 3.6e-21 74.9 0.0 1.9 2 0 0 2 2 2 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal MMR_HSR1 PF01926.18 EDO07130.1 - 1.5e-18 66.8 0.1 5.7e-18 64.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO07130.1 - 2e-08 33.6 0.0 3.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 EDO07130.1 - 0.0005 19.2 0.1 0.00081 18.5 0.1 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EDO07130.1 - 0.00052 19.2 0.2 0.0011 18.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDO07130.1 - 0.00057 19.7 0.1 0.28 10.9 0.4 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EDO07130.1 - 0.0011 19.4 0.0 0.0045 17.4 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 EDO07130.1 - 0.032 13.6 0.1 6.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Ras family GTP_EFTU PF00009.22 EDO07130.1 - 0.033 13.6 0.0 0.84 9.0 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EDO07130.1 - 0.042 13.0 0.1 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.24 EDO07131.1 - 3.5e-07 30.4 0.0 5.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PROCN PF08083.6 EDO07133.1 - 1.8e-217 721.6 6.5 2.6e-217 721.1 4.5 1.2 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EDO07133.1 - 4.3e-124 412.3 0.3 6.8e-124 411.6 0.2 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EDO07133.1 - 4.3e-93 308.9 1.9 8.6e-93 307.9 1.3 1.5 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EDO07133.1 - 1e-78 262.2 6.2 1.1e-78 262.1 2.4 2.5 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EDO07133.1 - 3.3e-69 230.7 0.1 6.1e-69 229.8 0.0 1.4 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EDO07133.1 - 6.2e-43 144.5 0.2 1.5e-42 143.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EDO07133.1 - 1.6e-33 115.0 0.0 4.8e-33 113.5 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain Proteasome PF00227.21 EDO07134.1 - 9.1e-38 129.4 0.1 1.9e-37 128.3 0.0 1.5 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO07134.1 - 1.6e-13 49.7 0.1 2.6e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-CCCH PF00642.19 EDO07135.1 - 2.3e-11 43.0 13.3 7e-06 25.5 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EDO07135.1 - 6.5e-09 35.5 0.0 2.2e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO07135.1 - 0.00029 20.4 0.0 0.00067 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRV_FeS PF05484.6 EDO07135.1 - 0.2 11.2 3.0 6 6.5 0.0 2.5 2 0 0 2 2 2 0 LRV protein FeS4 cluster Pkinase PF00069.20 EDO07137.1 - 1.6e-36 125.8 0.0 3.2e-36 124.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO07137.1 - 6.8e-25 87.6 0.0 1.3e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO07137.1 - 0.00028 19.9 0.0 0.00045 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2367 PF10164.4 EDO07138.1 - 0.093 12.5 0.0 0.17 11.7 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) SEP PF08059.8 EDO07139.1 - 1.4e-16 60.5 0.0 3.2e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 SEP domain ubiquitin PF00240.18 EDO07139.1 - 0.0035 16.6 0.1 0.092 12.1 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin family PBP_dimer PF03717.10 EDO07142.1 - 0.04 13.9 0.6 0.068 13.2 0.4 1.3 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain PhnA_Zn_Ribbon PF08274.7 EDO07142.1 - 0.15 11.8 4.2 2.1 8.1 0.1 2.9 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DZR PF12773.2 EDO07142.1 - 0.15 11.8 1.4 0.47 10.3 1.0 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 EDO07142.1 - 0.31 11.0 0.1 0.31 11.0 0.1 2.3 2 0 0 2 2 2 0 zinc-finger zf-ribbon_3 PF13248.1 EDO07142.1 - 8.8 5.6 8.0 68 2.8 5.5 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Asp PF00026.18 EDO07143.1 - 1e-61 208.9 0.0 1.7e-61 208.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDO07143.1 - 2.7e-05 24.2 0.0 9.7e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EDO07143.1 - 0.068 13.6 0.1 30 5.1 0.1 3.2 2 1 0 2 2 2 0 Aspartyl protease Methyltransf_8 PF05148.10 EDO07144.1 - 3.9e-30 105.1 0.5 2.1e-22 79.8 0.0 2.0 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EDO07144.1 - 6.8e-05 23.2 0.0 8.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO07144.1 - 0.0025 16.9 0.0 0.0062 15.6 0.0 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family VESA1_N PF12785.2 EDO07145.1 - 2.8e-206 685.9 17.4 2.8e-206 685.9 12.0 2.3 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 Baculo_PEP_C PF04513.7 EDO07145.1 - 0.14 11.9 0.3 1.2 8.9 0.0 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.6 EDO07145.1 - 0.35 11.3 0.1 6.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal ALIX_LYPXL_bnd PF13949.1 EDO07145.1 - 0.46 9.4 0.1 0.81 8.5 0.1 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF4175 PF13779.1 EDO07145.1 - 5.8 4.4 4.0 9 3.8 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) VESA1_N PF12785.2 EDO07146.1 - 5e-184 612.5 27.8 3.1e-121 405.5 3.0 3.6 4 1 1 5 5 5 2 Variant erythrocyte surface antigen-1 Baculo_PEP_C PF04513.7 EDO07146.1 - 0.003 17.3 0.1 0.36 10.6 0.0 3.0 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EDO07146.1 - 0.013 15.2 0.6 1.1 9.0 0.1 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_21 PF09976.4 EDO07146.1 - 0.052 13.4 3.9 0.094 12.6 1.8 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_27 PF13514.1 EDO07146.1 - 0.053 11.2 0.1 0.083 10.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain DegS PF05384.6 EDO07146.1 - 0.099 11.8 0.5 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 Sensor protein DegS DUF3584 PF12128.3 EDO07146.1 - 0.32 8.2 1.9 0.39 7.9 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) HisKA_3 PF07730.8 EDO07146.1 - 0.39 11.0 0.3 6.9 7.1 0.0 2.9 2 0 0 2 2 2 0 Histidine kinase ApoLp-III PF07464.6 EDO07146.1 - 0.95 9.4 8.8 2.1 8.3 2.2 2.8 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Spc7 PF08317.6 EDO07146.1 - 4.6 5.7 5.8 4.3 5.9 1.2 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein F-box-like_2 PF13013.1 EDO07147.1 - 5e-12 45.5 0.7 1.2e-07 31.4 0.0 2.7 1 1 2 3 3 3 2 F-box-like domain Sec8_exocyst PF04048.9 EDO07148.1 - 0.0063 16.1 4.2 2.5 7.7 0.2 3.0 2 1 1 3 3 3 1 Sec8 exocyst complex component specific domain NPV_P10 PF05531.7 EDO07148.1 - 0.013 15.7 0.1 5 7.4 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 EDO07148.1 - 0.013 14.1 1.3 0.018 13.7 0.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Holin_LLH PF09682.5 EDO07148.1 - 0.014 15.4 2.9 0.019 15.0 2.0 1.2 1 0 0 1 1 1 0 Phage holin protein (Holin_LLH) Enolase_C PF00113.17 EDO07148.1 - 0.027 13.4 0.8 0.035 13.0 0.5 1.1 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain IFT57 PF10498.4 EDO07148.1 - 0.029 13.0 0.4 0.035 12.8 0.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 WEMBL PF05701.6 EDO07148.1 - 0.036 12.5 4.4 0.053 11.9 3.0 1.2 1 1 0 1 1 1 0 Weak chloroplast movement under blue light GTPase_Cys_C PF12631.2 EDO07148.1 - 0.053 13.9 0.1 0.75 10.2 0.0 2.2 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE ApoLp-III PF07464.6 EDO07148.1 - 0.058 13.4 5.2 0.3 11.1 3.6 2.0 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.7 EDO07148.1 - 0.059 13.1 1.6 0.57 9.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 EDO07148.1 - 0.059 13.1 0.0 0.2 11.4 0.0 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-SNARE PF05008.10 EDO07148.1 - 0.067 13.3 0.3 1.6 8.9 0.1 2.6 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus NusA_N PF08529.6 EDO07148.1 - 0.071 13.1 0.5 0.09 12.7 0.3 1.3 1 1 0 1 1 1 0 NusA N-terminal domain DUF651 PF04895.7 EDO07148.1 - 0.12 12.0 0.0 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF651) HsbA PF12296.3 EDO07148.1 - 0.12 12.2 0.6 0.24 11.2 0.1 1.7 1 1 0 1 1 1 0 Hydrophobic surface binding protein A PMEI PF04043.10 EDO07148.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor LXG PF04740.7 EDO07148.1 - 0.15 11.7 0.4 0.23 11.2 0.2 1.3 1 1 0 1 1 1 0 LXG domain of WXG superfamily DUF948 PF06103.6 EDO07148.1 - 0.18 11.7 0.9 2.1 8.2 0.3 2.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) zf-ZPR1 PF03367.8 EDO07148.1 - 0.18 10.9 1.8 3.5 6.7 0.1 2.2 1 1 1 2 2 2 0 ZPR1 zinc-finger domain Kinocilin PF15033.1 EDO07148.1 - 0.4 10.2 2.0 4.8 6.7 0.2 2.3 1 1 1 2 2 2 0 Kinocilin protein Clp_N PF02861.15 EDO07148.1 - 4.5 7.2 6.0 1.8 8.5 0.2 2.7 3 0 0 3 3 3 0 Clp amino terminal domain Seryl_tRNA_N PF02403.17 EDO07148.1 - 6.3 6.8 8.8 18 5.3 4.1 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain VESA1_N PF12785.2 EDO07149.1 - 8e-163 542.6 21.0 8e-163 542.6 14.5 1.9 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 Baculo_PEP_C PF04513.7 EDO07149.1 - 0.18 11.5 0.0 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4175 PF13779.1 EDO07149.1 - 5.5 4.5 7.2 8.1 3.9 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) F-box-like_2 PF13013.1 EDO07150.1 - 0.00078 19.1 0.1 0.0022 17.6 0.0 1.7 1 1 1 2 2 2 1 F-box-like domain DUF2076 PF09849.4 EDO07150.1 - 0.04 13.9 0.1 0.052 13.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) F-box-like_2 PF13013.1 EDO07151.1 - 0.00068 19.3 0.0 0.0028 17.3 0.0 1.9 1 1 1 2 2 2 1 F-box-like domain SLIDE PF09111.5 EDO07151.1 - 0.14 11.9 1.2 16 5.2 0.0 3.2 4 0 0 4 4 4 0 SLIDE VESA1_N PF12785.2 EDO07152.1 - 8.1e-23 81.1 13.8 8.1e-23 81.1 9.6 4.8 3 1 1 4 4 4 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO07153.1 - 6.4e-225 747.4 17.0 6.4e-225 747.4 11.8 2.4 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 GTPase_Cys_C PF12631.2 EDO07153.1 - 0.00045 20.5 4.7 1.3 9.4 0.0 4.0 4 0 0 4 4 3 2 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF1110 PF06533.7 EDO07153.1 - 0.11 12.2 1.5 0.24 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1110) THOC7 PF05615.8 EDO07153.1 - 0.19 12.0 0.1 0.19 12.0 0.1 3.1 3 1 0 3 3 3 0 Tho complex subunit 7 DUF2524 PF10732.4 EDO07153.1 - 0.23 11.5 0.1 3.5 7.7 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) Syntaxin-6_N PF09177.6 EDO07153.1 - 0.31 11.4 3.5 0.43 11.0 0.0 2.8 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.7 EDO07153.1 - 0.36 10.6 3.1 25 4.6 0.1 3.4 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HisKA_3 PF07730.8 EDO07153.1 - 0.46 10.8 0.4 60 4.0 0.0 3.1 2 0 0 2 2 2 0 Histidine kinase Sec8_exocyst PF04048.9 EDO07153.1 - 0.56 9.8 2.0 26 4.4 0.1 2.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain PEP-utilisers_N PF05524.8 EDO07153.1 - 0.82 9.4 4.0 12 5.7 0.1 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4164 PF13747.1 EDO07153.1 - 0.97 9.6 7.2 3.1 8.0 2.6 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) HrpB7 PF09486.5 EDO07153.1 - 1.7 8.5 4.9 21 5.0 0.2 2.8 3 0 0 3 3 2 0 Bacterial type III secretion protein (HrpB7) DUF4618 PF15397.1 EDO07153.1 - 2 7.7 3.4 13 5.0 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) COG2 PF06148.6 EDO07153.1 - 2.4 8.0 3.6 38 4.1 0.0 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF883 PF05957.8 EDO07153.1 - 3.8 7.9 9.6 2.3 8.6 0.1 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.7 EDO07153.1 - 5.3 6.8 5.5 16 5.3 0.2 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) TSP_1 PF00090.14 EDO07154.1 - 0.0054 16.8 3.8 0.0054 16.8 2.6 2.5 3 0 0 3 3 3 1 Thrombospondin type 1 domain WD40 PF00400.27 EDO07155.1 - 3.6e-09 36.1 15.1 0.00077 19.2 0.1 6.1 6 1 0 6 6 6 3 WD domain, G-beta repeat DUF763 PF05559.6 EDO07155.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Tfb2 PF03849.9 EDO07156.1 - 5.4e-43 147.0 4.8 7.8e-29 100.4 1.5 3.0 1 1 1 2 2 2 2 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EDO07156.1 - 1.3e-05 24.9 0.0 3.3e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain PH PF00169.24 EDO07157.1 - 0.00028 21.0 0.3 0.00054 20.1 0.2 1.5 1 0 0 1 1 1 1 PH domain Treacle PF03546.9 EDO07157.1 - 0.0056 15.5 0.4 0.0068 15.2 0.3 1.1 1 0 0 1 1 1 1 Treacher Collins syndrome protein Treacle POP1 PF06978.6 EDO07157.1 - 0.045 13.4 0.6 0.066 12.8 0.4 1.3 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 EFG_C PF00679.19 EDO07157.1 - 0.092 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Elongation factor G C-terminus Synaptobrevin PF00957.16 EDO07158.1 - 1.1e-06 28.1 1.5 2.3e-06 27.0 1.1 1.6 1 0 0 1 1 1 1 Synaptobrevin I_LWEQ PF01608.12 EDO07158.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 I/LWEQ domain Nucleoporin_C PF03177.9 EDO07158.1 - 0.034 12.6 0.6 0.046 12.2 0.4 1.1 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal LSM PF01423.17 EDO07159.1 - 1.6e-12 46.8 0.0 2e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDO07159.1 - 0.00035 20.4 0.0 0.00036 20.3 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Pribosyltran_N PF13793.1 EDO07160.1 - 1.8e-38 130.8 0.0 1.7e-36 124.4 0.0 2.6 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EDO07160.1 - 1.1e-16 61.1 1.2 2.1e-16 60.2 0.7 1.5 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EDO07160.1 - 2.6e-08 33.6 0.2 5.1e-08 32.6 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EDO07160.1 - 0.00013 21.2 0.1 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PGK PF00162.14 EDO07161.1 - 2.1e-139 464.3 0.1 2.4e-139 464.1 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Ribosomal_L29 PF00831.18 EDO07163.1 - 1.7e-18 66.0 0.8 1.7e-18 66.0 0.6 1.8 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EDO07163.1 - 0.00023 21.4 1.8 0.00027 21.1 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF2508 PF10704.4 EDO07163.1 - 0.011 15.8 3.6 0.033 14.3 2.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2508) TMP_2 PF06791.8 EDO07163.1 - 0.019 14.5 0.2 0.023 14.3 0.1 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein Macro PF01661.16 EDO07163.1 - 0.12 12.3 0.2 0.13 12.1 0.2 1.2 1 0 0 1 1 1 0 Macro domain Phage_DsbA PF11126.3 EDO07163.1 - 0.21 11.6 1.5 0.27 11.3 0.0 1.9 3 0 0 3 3 3 0 Transcriptional regulator DsbA Antimicrobial_3 PF08025.6 EDO07163.1 - 0.22 11.2 1.0 1.4 8.6 0.7 2.2 1 1 0 1 1 1 0 Spider antimicrobial peptide ADK PF00406.17 EDO07164.1 - 2.9e-30 105.1 0.0 3.7e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EDO07164.1 - 9.3e-08 32.4 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO07164.1 - 1.1e-07 32.7 0.0 2.7e-07 31.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EDO07164.1 - 5.4e-05 23.0 0.0 9.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.9 EDO07164.1 - 0.0034 16.9 1.1 0.0081 15.8 0.8 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA PF00004.24 EDO07164.1 - 0.016 15.3 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDO07164.1 - 0.041 12.9 0.0 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus SKI PF01202.17 EDO07164.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase RRM_1 PF00076.17 EDO07165.1 - 1.2e-11 44.0 0.0 1.6e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07165.1 - 1.4e-10 41.0 0.0 1.9e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07165.1 - 1.9e-09 37.2 0.0 4.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EAP30 PF04157.11 EDO07166.1 - 1.4e-17 63.5 2.1 1.4e-17 63.5 1.5 1.9 2 0 0 2 2 2 1 EAP30/Vps36 family Pox_E2-like PF04497.7 EDO07166.1 - 0.0081 14.2 2.9 0.012 13.6 2.0 1.2 1 0 0 1 1 1 1 Poxviridae protein ABC_tran PF00005.22 EDO07168.1 - 1.2e-37 129.2 3.6 5.1e-19 68.9 0.0 4.5 5 0 0 5 5 4 3 ABC transporter AAA_21 PF13304.1 EDO07168.1 - 6.2e-23 82.1 22.2 5.6e-11 42.9 5.1 4.2 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EDO07168.1 - 6.1e-13 48.5 7.1 1.5e-07 30.8 0.5 3.9 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EDO07168.1 - 5.7e-11 42.1 8.1 0.0027 16.8 0.1 4.5 4 0 0 4 4 4 4 AAA ATPase domain AAA_29 PF13555.1 EDO07168.1 - 1.1e-09 37.6 0.3 0.0013 18.2 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EDO07168.1 - 1.7e-07 31.4 0.0 0.042 13.8 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 EDO07168.1 - 2.6e-06 27.9 9.6 0.01 16.2 3.3 3.3 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EDO07168.1 - 1.6e-05 24.1 0.2 0.046 12.9 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EDO07168.1 - 2.1e-05 25.0 0.0 0.21 12.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EDO07168.1 - 6.1e-05 23.1 1.7 1.5 9.0 0.0 4.4 4 1 0 4 4 4 1 AAA domain MobB PF03205.9 EDO07168.1 - 0.00086 19.0 0.0 2 8.1 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EDO07168.1 - 0.0013 19.5 0.3 5.1 7.9 0.0 3.5 4 0 0 4 4 3 0 AAA domain MMR_HSR1 PF01926.18 EDO07168.1 - 0.0014 18.5 0.2 0.79 9.6 0.1 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.9 EDO07168.1 - 0.0028 17.3 0.1 4.1 7.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) ArgK PF03308.11 EDO07168.1 - 0.0032 16.2 0.0 1.2 7.8 0.0 2.4 2 0 0 2 2 2 1 ArgK protein SbcCD_C PF13558.1 EDO07168.1 - 0.0066 16.3 0.0 12 5.8 0.0 3.4 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Fcf1 PF04900.7 EDO07168.1 - 0.0068 16.4 0.3 0.039 14.0 0.0 2.1 2 0 0 2 2 2 1 Fcf1 AAA_10 PF12846.2 EDO07168.1 - 0.01 15.3 0.3 6.7 6.0 0.2 3.9 3 1 0 3 3 3 0 AAA-like domain AAA_28 PF13521.1 EDO07168.1 - 0.011 15.7 0.2 4 7.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EDO07168.1 - 0.012 15.2 0.0 2.9 7.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain TEX12 PF15219.1 EDO07168.1 - 0.014 15.3 0.6 0.059 13.3 0.0 2.3 2 0 0 2 2 2 0 Testis-expressed 12 AAA_30 PF13604.1 EDO07168.1 - 0.02 14.4 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EDO07168.1 - 0.021 14.3 0.0 5 6.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 EDO07168.1 - 0.024 14.2 0.1 8.1 6.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EDO07168.1 - 0.034 13.5 0.0 9.5 5.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.8 EDO07168.1 - 0.04 12.8 4.1 0.079 11.8 0.1 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EDO07168.1 - 0.04 13.3 0.2 5.6 6.4 0.0 3.5 4 0 0 4 4 4 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EDO07168.1 - 0.06 13.5 0.0 14 5.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 EDO07168.1 - 0.061 13.5 0.1 27 4.9 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EDO07168.1 - 0.064 12.1 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 EDO07168.1 - 0.07 12.2 0.1 0.55 9.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EDO07168.1 - 0.074 12.6 0.0 9.6 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EDO07168.1 - 0.12 11.8 0.0 6.3 6.1 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 EDO07168.1 - 0.15 11.5 0.0 8.5 5.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF4215 PF13948.1 EDO07169.1 - 0.14 12.4 0.0 0.14 12.4 0.0 4.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4215) PLU-1 PF08429.6 EDO07170.1 - 4.3e-84 282.2 2.0 2.1e-83 279.9 0.2 2.2 2 1 0 2 2 2 2 PLU-1-like protein ThiF PF00899.16 EDO07171.1 - 2.5e-17 62.9 0.0 4.3e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family tRNA-synt_2b PF00587.20 EDO07172.1 - 3.8e-44 150.2 0.1 6.6e-44 149.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDO07172.1 - 1.3e-19 69.8 0.7 2.4e-19 69.0 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.9 EDO07172.1 - 5.9e-06 26.0 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Transket_pyr PF02779.19 EDO07173.1 - 2.8e-41 140.9 0.0 3.8e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EDO07173.1 - 4.8e-36 123.4 0.0 8.9e-36 122.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PcfK PF14058.1 EDO07174.1 - 0.16 12.1 2.7 0.29 11.2 1.8 1.4 1 0 0 1 1 1 0 PcfK-like protein MMS19_N PF14500.1 EDO07175.1 - 8.5e-31 107.1 0.9 1.7e-30 106.1 0.5 1.7 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II PhyH PF05721.8 EDO07175.1 - 1.4e-08 35.0 0.0 3.3e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Imm6 PF14434.1 EDO07175.1 - 0.044 13.4 0.5 0.12 12.0 0.4 1.8 1 0 0 1 1 1 0 Immunity protein Imm6 Tim17 PF02466.14 EDO07176.1 - 6.8e-32 110.1 3.7 8.3e-32 109.9 2.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Tim44 PF04280.10 EDO07177.1 - 8e-31 106.9 0.0 5.3e-30 104.3 0.0 2.2 3 0 0 3 3 3 1 Tim44-like domain DUF3702 PF12486.3 EDO07177.1 - 0.092 12.4 1.0 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 ImpA domain protein LSM PF01423.17 EDO07178.1 - 1.7e-14 53.1 1.2 2.4e-14 52.6 0.8 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDO07178.1 - 0.021 14.7 0.2 0.027 14.4 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.12 EDO07178.1 - 0.13 11.9 0.3 0.25 11.0 0.2 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain GrpE PF01025.14 EDO07180.1 - 1.3e-43 148.3 5.3 1.9e-43 147.9 3.7 1.3 1 1 0 1 1 1 1 GrpE V_ATPase_I PF01496.14 EDO07180.1 - 0.0019 16.1 5.1 0.0023 15.8 3.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family COG5 PF10392.4 EDO07180.1 - 0.035 14.0 0.6 0.071 13.0 0.4 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 YtzH PF14165.1 EDO07180.1 - 0.052 13.7 0.9 0.14 12.4 0.2 2.0 2 0 0 2 2 2 0 YtzH-like protein RRS1 PF04939.7 EDO07181.1 - 1e-52 177.9 0.0 1e-52 177.9 0.0 1.4 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) RRM_1 PF00076.17 EDO07182.1 - 3.7e-78 257.1 1.1 8.4e-20 70.1 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07182.1 - 4.8e-51 170.6 0.1 9e-14 51.2 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07182.1 - 1.3e-35 121.0 0.4 3.7e-09 36.2 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EDO07182.1 - 2.3e-29 100.8 1.6 2e-28 97.8 0.5 2.8 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 EDO07182.1 - 0.00019 21.2 0.3 5.4 6.9 0.0 3.8 3 1 0 3 3 3 2 RNA binding motif RNA_bind PF08675.6 EDO07182.1 - 0.00035 20.4 0.1 0.039 13.9 0.0 3.2 3 0 0 3 3 3 1 RNA binding domain Nup35_RRM_2 PF14605.1 EDO07182.1 - 0.0013 18.5 0.1 49 3.8 0.0 4.2 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EDO07182.1 - 0.0043 16.7 0.1 0.36 10.5 0.0 3.2 2 1 1 3 3 3 1 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 EDO07184.1 - 1.8e-36 125.6 0.1 6.2e-31 107.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO07184.1 - 1.6e-22 79.8 0.1 1.4e-17 63.6 0.0 2.3 2 1 1 3 3 3 2 Protein tyrosine kinase Choline_kinase PF01633.15 EDO07185.1 - 5.7e-40 137.1 0.2 8.3e-40 136.6 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EDO07185.1 - 4e-13 49.6 0.0 5.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EDO07185.1 - 0.00013 21.0 0.1 0.00027 20.0 0.0 1.5 2 0 0 2 2 2 1 Fructosamine kinase EcKinase PF02958.15 EDO07185.1 - 0.001 18.2 0.1 0.0018 17.4 0.1 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 EDO07185.1 - 0.002 17.4 0.4 0.017 14.4 0.1 2.2 2 0 0 2 2 2 1 RIO1 family SapB_1 PF05184.10 EDO07185.1 - 0.026 14.3 0.0 2.5 8.0 0.0 2.9 2 0 0 2 2 2 0 Saposin-like type B, region 1 Choline_kinase PF01633.15 EDO07186.1 - 2.5e-42 144.8 0.3 3.5e-42 144.3 0.2 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EDO07186.1 - 3.9e-10 39.8 0.0 6.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EDO07186.1 - 0.0024 17.0 0.1 0.0045 16.1 0.1 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 EDO07186.1 - 0.005 15.8 0.0 0.0087 15.0 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase DUF4546 PF15079.1 EDO07187.1 - 0.32 10.1 1.7 0.51 9.4 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) LSM PF01423.17 EDO07188.1 - 7.9e-10 38.1 0.0 1.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDO07188.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 Ataxin 2 SM domain AAA PF00004.24 EDO07190.1 - 3.8e-95 315.1 0.0 3.2e-46 156.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EDO07190.1 - 5.7e-23 80.6 0.2 1.5e-22 79.3 0.1 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_16 PF13191.1 EDO07190.1 - 1.4e-12 47.9 0.1 9.2e-05 22.5 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 EDO07190.1 - 2.2e-12 46.5 0.0 2.8e-05 23.3 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EDO07190.1 - 2.2e-12 47.0 0.0 6.1e-06 26.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EDO07190.1 - 4.4e-12 46.8 0.0 2.6e-05 25.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EDO07190.1 - 5.2e-12 46.0 0.0 2.8e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EDO07190.1 - 1e-11 45.0 0.1 0.00047 20.2 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EDO07190.1 - 4.5e-11 42.6 0.4 4.3e-06 26.5 0.0 3.4 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EDO07190.1 - 6.2e-09 35.8 0.0 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EDO07190.1 - 1.3e-08 34.0 0.0 0.00048 18.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 EDO07190.1 - 1.7e-08 33.7 0.0 0.0015 17.6 0.0 2.6 2 1 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EDO07190.1 - 3.1e-08 33.2 0.9 0.077 12.3 0.0 3.7 2 1 0 3 3 3 2 AAA domain CDC48_2 PF02933.12 EDO07190.1 - 4.5e-08 32.6 0.0 1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.1 EDO07190.1 - 2.4e-07 31.0 0.0 0.018 15.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EDO07190.1 - 6.7e-07 29.4 0.0 0.016 15.4 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 EDO07190.1 - 7.6e-07 28.7 2.0 0.016 14.9 0.1 3.1 3 0 0 3 3 3 2 Part of AAA domain Mg_chelatase PF01078.16 EDO07190.1 - 8.1e-07 28.4 0.2 0.03 13.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EDO07190.1 - 1e-06 28.6 0.0 0.036 13.7 0.0 3.6 2 2 2 4 4 4 2 Archaeal ATPase IstB_IS21 PF01695.12 EDO07190.1 - 1.2e-06 28.0 0.0 0.047 13.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 EDO07190.1 - 5.3e-06 26.4 0.0 0.14 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EDO07190.1 - 2.4e-05 24.0 0.0 0.39 10.3 0.0 3.6 3 1 0 4 4 4 2 NACHT domain Sigma54_activ_2 PF14532.1 EDO07190.1 - 3.4e-05 23.9 0.0 0.093 12.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 EDO07190.1 - 5.3e-05 22.8 0.1 0.31 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 EDO07190.1 - 5.6e-05 23.4 0.0 0.22 11.7 0.0 3.0 2 1 0 2 2 2 2 ABC transporter KaiC PF06745.8 EDO07190.1 - 6.1e-05 22.2 0.2 2 7.4 0.0 3.3 2 1 1 3 3 3 1 KaiC Viral_helicase1 PF01443.13 EDO07190.1 - 9.3e-05 22.0 0.0 0.0096 15.4 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 EDO07190.1 - 0.0002 20.2 0.0 0.44 9.3 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EDO07190.1 - 0.00025 20.0 0.1 0.6 8.9 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.21 EDO07190.1 - 0.00055 19.4 0.0 0.78 9.1 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain Vps4_C PF09336.5 EDO07190.1 - 0.00062 19.6 0.3 0.017 15.0 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ResIII PF04851.10 EDO07190.1 - 0.00081 19.2 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EDO07190.1 - 0.0012 18.1 0.2 1.2 8.3 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.8 EDO07190.1 - 0.0012 17.8 0.0 0.49 9.2 0.0 2.6 3 0 0 3 3 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 EDO07190.1 - 0.0017 17.9 0.0 2.1 7.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 EDO07190.1 - 0.0024 17.5 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein SKI PF01202.17 EDO07190.1 - 0.0031 17.4 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.10 EDO07190.1 - 0.0045 16.7 0.1 2.6 7.7 0.0 3.6 2 1 0 3 3 3 1 NTPase DUF2075 PF09848.4 EDO07190.1 - 0.0065 15.4 0.0 0.99 8.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EDO07190.1 - 0.018 14.6 0.0 6.5 6.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain UFD1 PF03152.9 EDO07190.1 - 0.021 13.9 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 UPF0079 PF02367.12 EDO07190.1 - 0.022 14.4 0.1 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EDO07190.1 - 0.025 14.0 0.6 6.8 6.0 0.0 3.3 2 1 1 3 3 3 0 AAA-like domain Cytidylate_kin2 PF13189.1 EDO07190.1 - 0.036 13.9 0.0 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_23 PF13476.1 EDO07190.1 - 0.053 13.8 0.0 9.6 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 EDO07190.1 - 0.059 12.8 0.2 5.4 6.4 0.1 3.2 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_29 PF13555.1 EDO07190.1 - 0.065 12.7 0.0 5.3 6.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.1 EDO07190.1 - 0.083 12.4 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EDO07190.1 - 0.085 12.3 0.0 19 4.6 0.0 3.2 2 1 1 3 3 3 0 DEAD/DEAH box helicase Molydop_binding PF01568.16 EDO07190.1 - 0.09 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain KTI12 PF08433.5 EDO07190.1 - 0.12 11.5 0.0 8.4 5.5 0.0 2.6 3 0 0 3 3 2 0 Chromatin associated protein KTI12 SRR1 PF07985.7 EDO07191.1 - 4.5e-16 58.5 0.1 2.7e-15 56.0 0.2 2.1 2 0 0 2 2 2 1 SRR1 SNF2_N PF00176.18 EDO07192.1 - 2.6e-76 256.2 0.0 4.6e-76 255.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EDO07192.1 - 2.3e-32 111.2 0.1 5.2e-32 110.0 0.0 1.7 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.26 EDO07192.1 - 5e-17 61.5 0.0 1.3e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO07192.1 - 3.7e-10 39.9 0.2 1.3e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDO07192.1 - 2.4e-07 30.3 0.0 5.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 EDO07192.1 - 0.0055 16.7 0.0 0.025 14.6 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain AAA_14 PF13173.1 EDO07192.1 - 0.01 15.7 0.3 0.04 13.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EDO07192.1 - 0.56 9.7 3.8 0.78 9.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain Fumble PF03630.9 EDO07193.1 - 1.6e-21 76.5 0.1 1.2e-20 73.7 0.0 2.2 2 1 0 2 2 2 1 Fumble HSP90 PF00183.13 EDO07194.1 - 1.9e-124 416.0 16.3 3.7e-122 408.4 6.5 2.4 2 1 1 3 3 3 2 Hsp90 protein HATPase_c_3 PF13589.1 EDO07194.1 - 2.8e-13 49.7 0.4 9e-13 48.0 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDO07194.1 - 1.3e-07 31.3 0.1 3.7e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YyzF PF14116.1 EDO07194.1 - 0.012 15.5 1.4 0.046 13.6 0.9 2.0 1 0 0 1 1 1 0 YyzF-like protein DUF4413 PF14372.1 EDO07194.1 - 0.046 13.7 3.4 0.098 12.6 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) RNA_pol_Rpb1_5 PF04998.12 EDO07194.1 - 6.9 5.8 7.0 12 5.0 0.9 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 TRAPPC-Trs85 PF12739.2 EDO07195.1 - 1.2e-09 37.3 0.0 1.9e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit CARDB PF07705.6 EDO07195.1 - 0.038 14.0 0.4 0.23 11.5 0.0 2.5 2 0 0 2 2 2 0 CARDB 5-FTHF_cyc-lig PF01812.15 EDO07196.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family Elong-fact-P_C PF09285.6 EDO07197.1 - 1.4e-09 37.1 0.0 3.4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.7 EDO07197.1 - 3.9e-07 29.8 0.1 7.9e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.15 EDO07197.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain C9orf72-like PF15019.1 EDO07198.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 C9orf72-like protein family CDC14 PF08045.6 EDO07198.1 - 0.024 13.7 0.7 0.044 12.8 0.5 1.6 1 1 0 1 1 1 0 Cell division control protein 14, SIN component TRF PF08558.5 EDO07198.1 - 0.03 13.6 0.2 0.067 12.5 0.1 1.6 1 1 1 2 2 2 0 Telomere repeat binding factor (TRF) OSCP PF00213.13 EDO07201.1 - 6.8e-41 139.9 0.0 7.8e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit p25-alpha PF05517.7 EDO07202.1 - 1.1e-25 90.6 0.0 1.2e-25 90.5 0.0 1.0 1 0 0 1 1 1 1 p25-alpha NDUF_B12 PF08122.7 EDO07202.1 - 0.053 13.2 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF3791 PF12668.2 EDO07202.1 - 0.13 11.9 0.1 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) Prefoldin PF02996.12 EDO07203.1 - 3.7e-22 78.2 0.1 4.8e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Baculo_PEP_C PF04513.7 EDO07203.1 - 0.0058 16.4 0.2 1.1 9.0 0.1 2.1 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.4 EDO07203.1 - 0.043 13.7 0.1 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein NPV_P10 PF05531.7 EDO07203.1 - 0.049 13.8 0.1 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 EDO07203.1 - 0.16 12.1 0.8 13 5.9 0.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.6 EDO07203.1 - 0.19 12.1 1.0 5.5 7.4 0.0 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal RRM_1 PF00076.17 EDO07204.1 - 1.2e-20 72.9 0.0 1.7e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07204.1 - 8.7e-15 54.4 0.0 1.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07204.1 - 1.8e-08 34.0 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO07204.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Cofilin_ADF PF00241.15 EDO07205.1 - 3.2e-12 46.4 0.1 3.8e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HEAT PF02985.17 EDO07206.1 - 2.7e-08 33.1 0.5 0.15 12.2 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EDO07206.1 - 0.00042 20.6 0.1 6.4 7.2 0.0 3.6 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region Pkinase PF00069.20 EDO07206.1 - 0.00059 19.0 1.4 0.00093 18.4 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Ribosomal_L31e PF01198.14 EDO07207.1 - 1e-37 127.6 2.8 1.3e-37 127.2 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Helicase_C PF00271.26 EDO07208.1 - 2e-16 59.5 0.5 7.5e-16 57.7 0.3 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO07208.1 - 2.1e-09 37.1 0.5 3.5e-08 33.1 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Glutaredoxin2_C PF04399.8 EDO07208.1 - 0.083 12.4 0.0 0.87 9.1 0.0 2.3 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain E1-E2_ATPase PF00122.15 EDO07209.1 - 2e-20 72.8 2.0 3.2e-20 72.1 0.5 2.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EDO07209.1 - 3.2e-14 53.8 0.0 1.3e-12 48.6 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDO07209.1 - 4.6e-14 53.0 0.2 1.2e-13 51.6 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDO07209.1 - 0.029 13.8 0.0 0.091 12.2 0.0 1.8 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EDO07209.1 - 0.039 13.9 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit WD40 PF00400.27 EDO07212.1 - 5e-07 29.3 1.7 0.00031 20.4 0.0 4.0 3 0 0 3 3 3 1 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EDO07212.1 - 0.018 14.5 0.2 0.091 12.2 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Rpr2 PF04032.11 EDO07214.1 - 5.7e-24 83.7 0.4 9.3e-24 83.1 0.3 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain BaffR-Tall_bind PF09256.5 EDO07215.1 - 0.3 10.6 2.4 4.8 6.8 0.0 3.0 3 0 0 3 3 3 0 BAFF-R, TALL-1 binding TRAP_alpha PF03896.11 EDO07216.1 - 0.012 14.5 0.8 0.018 14.0 0.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.1 EDO07216.1 - 0.032 13.9 0.4 0.088 12.4 0.3 1.7 1 0 0 1 1 1 0 FAM176 family AIG1 PF04548.11 EDO07216.1 - 0.086 11.9 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family DUF2890 PF11081.3 EDO07216.1 - 0.71 9.9 5.9 0.59 10.1 3.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Hpt PF01627.18 EDO07218.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Hpt domain zf-RING_5 PF14634.1 EDO07219.1 - 0.02 14.5 12.0 0.02 14.5 8.3 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EDO07219.1 - 0.57 9.8 11.4 1.6 8.4 7.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Proteasome PF00227.21 EDO07220.1 - 1.7e-46 157.9 0.0 2e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit RNase_PH PF01138.16 EDO07221.1 - 0.072 13.4 0.4 0.13 12.5 0.3 1.6 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 Cyclin_N PF00134.18 EDO07222.1 - 0.00047 19.7 0.0 0.0012 18.4 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Syja_N PF02383.13 EDO07223.1 - 2.6e-74 249.8 0.1 3.8e-74 249.3 0.1 1.2 1 0 0 1 1 1 1 SacI homology domain CHCH PF06747.8 EDO07225.1 - 0.61 10.0 2.4 4 7.4 1.9 2.1 1 1 1 2 2 2 0 CHCH domain CwfJ_C_1 PF04677.10 EDO07227.1 - 4.6e-22 77.9 0.3 8.1e-22 77.1 0.2 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.17 EDO07227.1 - 7.2e-10 38.3 0.0 1.7e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07227.1 - 4.8e-09 36.0 0.0 8.6e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07227.1 - 0.0085 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3133 PF11331.3 EDO07227.1 - 0.024 14.1 0.2 0.055 13.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3133) RRM_3 PF08777.6 EDO07227.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Noc2 PF03715.8 EDO07228.1 - 1.3e-93 313.1 5.1 1.3e-93 313.1 3.5 1.8 2 0 0 2 2 2 1 Noc2p family DNA_pol_B PF00136.16 EDO07229.1 - 9.9e-129 430.1 0.7 1.7e-128 429.3 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EDO07229.1 - 1.9e-73 247.1 0.2 2.9e-73 246.5 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EDO07229.1 - 9.7e-21 73.5 7.8 9.7e-21 73.5 5.4 1.8 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 EDO07229.1 - 0.0039 15.9 0.2 0.0075 14.9 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral RNase_PH PF01138.16 EDO07230.1 - 8.1e-12 45.6 0.0 1.3e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EDO07230.1 - 5.4e-05 23.0 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF2400 PF09674.5 EDO07232.1 - 0.23 11.1 2.8 0.23 11.1 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2400) Sec61_beta PF03911.11 EDO07233.1 - 0.00012 21.7 0.1 0.00016 21.3 0.1 1.2 1 0 0 1 1 1 1 Sec61beta family MobB PF03205.9 EDO07235.1 - 0.0019 17.8 0.0 0.018 14.7 0.0 2.5 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 EDO07235.1 - 0.0022 17.2 0.0 0.0064 15.7 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_10 PF12846.2 EDO07235.1 - 0.0035 16.8 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EDO07235.1 - 0.0036 17.2 0.0 0.011 15.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EDO07235.1 - 0.007 17.1 0.0 0.018 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Clp1 PF06807.9 EDO07235.1 - 0.017 14.9 0.0 0.12 12.1 0.0 2.2 1 1 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 DUF1611 PF07755.6 EDO07235.1 - 0.021 13.4 0.0 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1611) AAA_19 PF13245.1 EDO07235.1 - 0.028 14.1 0.0 0.097 12.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain DAP3 PF10236.4 EDO07235.1 - 0.028 13.3 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_28 PF13521.1 EDO07235.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EDO07235.1 - 0.043 13.2 0.0 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EDO07235.1 - 0.1 12.9 0.1 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ribosomal_L4 PF00573.17 EDO07238.1 - 3.3e-52 176.6 0.0 4.3e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family zf-CCCH PF00642.19 EDO07239.1 - 0.14 11.8 6.0 0.078 12.6 2.4 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.19 EDO07240.1 - 0.14 11.8 6.0 0.078 12.6 2.4 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Med7 PF05983.6 EDO07241.1 - 4.8e-10 39.4 0.2 5.4e-10 39.2 0.1 1.0 1 0 0 1 1 1 1 MED7 protein KH_1 PF00013.24 EDO07242.1 - 4.9e-07 29.2 0.8 1.4e-06 27.8 0.5 1.8 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EDO07242.1 - 0.012 15.2 0.8 0.028 14.0 0.5 1.6 1 0 0 1 1 1 0 KH domain Cyto_heme_lyase PF01265.12 EDO07243.1 - 1.2e-45 156.2 0.3 4.5e-44 150.9 0.2 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase FRD2 PF03197.8 EDO07243.1 - 0.057 13.9 0.0 0.087 13.3 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage FRD2 protein zf-Tim10_DDP PF02953.10 EDO07244.1 - 9.5e-20 69.6 0.3 1.1e-19 69.4 0.2 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EDO07244.1 - 0.023 14.1 0.3 0.026 13.9 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) eIF-5a PF01287.15 EDO07245.1 - 1.2e-26 92.3 0.1 1.8e-26 91.8 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EDO07245.1 - 0.00088 18.9 0.2 0.003 17.2 0.1 2.1 2 0 0 2 2 2 1 KOW motif EFP_N PF08207.7 EDO07245.1 - 0.002 17.9 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Rad17 PF03215.10 EDO07246.1 - 1.2e-13 50.5 0.7 6.6e-05 21.7 0.1 3.4 3 1 0 3 3 3 3 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EDO07246.1 - 2.2e-05 25.2 0.0 5.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO07246.1 - 0.0059 16.9 0.0 0.034 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDO07246.1 - 0.0092 15.9 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EDO07246.1 - 0.018 15.2 0.1 0.12 12.5 0.0 2.4 1 1 2 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO07246.1 - 0.061 13.4 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EDO07246.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 EDO07246.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EDO07247.1 - 0.03 15.1 0.0 0.079 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDO07247.1 - 0.061 12.7 0.0 0.095 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDO07247.1 - 0.099 12.9 0.1 0.24 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EDO07247.1 - 0.11 11.5 0.2 6.3 5.8 0.1 2.1 2 0 0 2 2 2 0 KaiC TGF_beta_GS PF08515.7 EDO07247.1 - 0.3 10.4 1.6 0.73 9.2 1.1 1.7 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif CK_II_beta PF01214.13 EDO07249.1 - 2e-69 232.8 1.2 2.4e-69 232.5 0.8 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit IBR PF01485.16 EDO07249.1 - 0.068 13.0 0.8 0.24 11.2 0.6 1.9 1 1 0 1 1 1 0 IBR domain RIO1 PF01163.17 EDO07250.1 - 7.4e-56 188.4 0.0 1.6e-55 187.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EDO07250.1 - 0.022 14.5 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family FAINT PF04385.10 EDO07251.1 - 0.062 13.1 0.1 0.062 13.1 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function, DUF529 RRM_1 PF00076.17 EDO07252.1 - 1.9e-33 113.8 1.0 6.6e-16 57.7 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07252.1 - 2e-25 88.5 0.1 1e-12 47.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07252.1 - 4.2e-12 45.7 0.0 0.0001 22.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDO07252.1 - 0.00097 18.9 0.1 0.52 10.1 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif OB_RNB PF08206.6 EDO07252.1 - 0.14 11.6 3.8 1.7 8.2 0.0 2.9 3 0 0 3 3 3 0 Ribonuclease B OB domain Ras PF00071.17 EDO07253.1 - 4e-59 198.6 0.0 4.7e-59 198.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO07253.1 - 9.3e-19 68.0 0.0 1.4e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO07253.1 - 5.6e-12 45.2 0.1 6.3e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDO07253.1 - 7.4e-06 25.9 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EDO07253.1 - 1.2e-05 24.5 0.0 1.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO07253.1 - 0.00075 18.9 0.0 0.0047 16.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EDO07253.1 - 0.0039 16.8 0.0 0.013 15.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 EDO07253.1 - 0.017 15.2 0.0 0.077 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain DNA_pol_E_B PF04042.11 EDO07253.1 - 0.023 13.9 0.0 0.031 13.5 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B AAA_14 PF13173.1 EDO07253.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Proteasome PF00227.21 EDO07254.1 - 7.3e-52 175.4 0.2 8.9e-52 175.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit zf-C3HC4 PF00097.20 EDO07255.1 - 9.3e-08 31.6 5.2 9.3e-08 31.6 3.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO07255.1 - 1.1e-07 31.5 7.8 3.1e-07 30.1 5.4 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDO07255.1 - 1.3e-06 28.3 7.8 1.3e-06 28.3 5.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO07255.1 - 7.2e-06 25.5 4.9 7.2e-06 25.5 3.4 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO07255.1 - 9e-06 25.3 4.2 9e-06 25.3 2.9 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EDO07255.1 - 0.00035 20.6 4.4 0.0019 18.2 3.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EDO07255.1 - 0.00064 19.5 7.3 0.00064 19.5 5.0 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EDO07255.1 - 0.0012 18.5 4.0 0.0043 16.7 2.8 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EDO07255.1 - 0.0022 17.8 1.7 0.0047 16.7 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EDO07255.1 - 0.018 14.5 2.2 0.041 13.4 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 EDO07255.1 - 4.6 6.8 13.6 0.15 11.6 5.1 1.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger KH_1 PF00013.24 EDO07257.1 - 8.4e-18 63.7 4.1 1.3e-09 37.5 0.1 5.1 5 0 0 5 5 5 3 KH domain KH_3 PF13014.1 EDO07257.1 - 6.7e-09 35.1 2.7 5.5e-05 22.7 0.4 4.4 4 0 0 4 4 4 2 KH domain SLS PF14611.1 EDO07257.1 - 9.5e-06 25.1 0.5 0.00014 21.4 0.3 2.7 2 1 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 EDO07257.1 - 0.0075 15.7 0.0 0.032 13.8 0.0 2.1 1 0 0 1 1 1 1 KH domain DUF4370 PF14290.1 EDO07257.1 - 0.031 13.7 1.0 0.058 12.8 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4370) BMC PF00936.14 EDO07257.1 - 0.081 12.6 0.0 5.1 6.8 0.0 3.4 3 0 0 3 3 3 0 BMC domain XPC-binding PF09280.6 EDO07258.1 - 5.4e-22 77.0 5.8 1e-21 76.1 4.0 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 EDO07258.1 - 3.4e-19 68.0 4.4 9e-10 38.1 0.2 2.9 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.18 EDO07258.1 - 4.3e-10 38.8 0.5 7.5e-10 38.0 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EDO07258.1 - 2.6e-05 23.8 0.4 5e-05 22.8 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDO07258.1 - 0.0019 18.3 0.7 0.0032 17.6 0.1 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain HD_5 PF13487.1 EDO07258.1 - 0.018 15.0 0.2 1.4 8.9 0.2 2.7 2 0 0 2 2 2 0 HD domain mTERF PF02536.9 EDO07258.1 - 0.046 12.3 0.0 0.37 9.3 0.0 2.3 2 1 0 2 2 2 0 mTERF Rap1_C PF11626.3 EDO07258.1 - 0.047 13.5 0.0 0.54 10.1 0.0 2.5 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Jnk-SapK_ap_N PF09744.4 EDO07260.1 - 0.12 12.3 4.3 0.16 11.9 3.0 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Tubulin PF00091.20 EDO07261.1 - 1.2e-42 146.1 0.4 1.9e-42 145.5 0.3 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DUF4047 PF13256.1 EDO07261.1 - 0.014 15.3 0.0 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Tubulin_C PF03953.12 EDO07261.1 - 0.03 14.3 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Tubulin C-terminal domain Tubulin_3 PF14881.1 EDO07261.1 - 0.056 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.1 EDO07261.1 - 0.092 11.6 1.2 0.52 9.1 0.1 2.0 1 1 1 2 2 2 0 Tubulin like SNF2_N PF00176.18 EDO07262.1 - 2.8e-65 220.0 1.0 7.9e-65 218.5 0.2 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 EDO07262.1 - 8.6e-19 66.9 6.4 1e-08 34.6 0.1 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EDO07262.1 - 2e-15 56.3 0.1 9.3e-15 54.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO07262.1 - 6.9e-07 28.9 0.0 2.1e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4208 PF13907.1 EDO07262.1 - 0.0013 18.9 0.4 0.0013 18.9 0.3 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) AAA_22 PF13401.1 EDO07262.1 - 0.04 14.0 0.2 0.65 10.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain Thioredoxin PF00085.15 EDO07264.1 - 1.3e-27 95.4 0.0 2.1e-23 81.9 0.0 2.7 2 1 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EDO07264.1 - 7.1e-11 42.2 0.0 0.00016 21.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EDO07264.1 - 1.2e-09 38.3 0.2 3.2e-05 24.0 0.2 4.2 3 2 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDO07264.1 - 1.5e-05 25.0 0.1 0.0032 17.5 0.0 3.4 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EDO07264.1 - 0.00097 18.9 0.0 0.2 11.4 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_9 PF14595.1 EDO07264.1 - 0.031 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.1 EDO07264.1 - 0.032 14.2 0.0 0.084 12.9 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Glycos_trans_3N PF02885.12 EDO07264.1 - 0.09 12.3 0.0 5.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Thioredoxin_4 PF13462.1 EDO07264.1 - 0.1 12.6 0.0 2 8.3 0.0 2.7 2 1 1 3 3 3 0 Thioredoxin GMP_synt_C PF00958.17 EDO07265.1 - 1.6e-29 101.4 0.1 3.5e-29 100.3 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EDO07265.1 - 9.8e-15 54.5 0.0 1.9e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EDO07265.1 - 8.4e-11 41.2 0.0 6.3e-09 35.0 0.0 2.2 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.16 EDO07265.1 - 1.4e-05 24.7 0.1 0.00042 19.8 0.0 2.3 2 0 0 2 2 2 1 Asparagine synthase tRNA_Me_trans PF03054.11 EDO07265.1 - 0.0021 16.7 0.0 0.0037 15.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.8 EDO07265.1 - 0.014 14.6 0.1 0.062 12.5 0.0 2.1 3 0 0 3 3 3 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.14 EDO07265.1 - 0.027 14.3 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Peptidase_C26 PF07722.8 EDO07265.1 - 0.099 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase C26 DRTGG PF07085.7 EDO07265.1 - 0.1 12.1 0.0 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 DRTGG domain UCR_14kD PF02271.11 EDO07266.1 - 1.6e-15 56.7 0.1 2.2e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit PTH2 PF01981.11 EDO07267.1 - 2.7e-17 62.4 1.3 3e-17 62.3 0.2 1.6 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 TFIIS_C PF01096.13 EDO07268.1 - 3.1e-13 49.1 3.6 3.1e-13 49.1 2.5 2.4 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF3895 PF13034.1 EDO07268.1 - 0.083 12.3 0.2 0.48 9.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3895) DZR PF12773.2 EDO07268.1 - 0.17 11.7 7.8 2.1 8.2 0.6 2.5 2 1 0 2 2 2 0 Double zinc ribbon Mu-like_Com PF10122.4 EDO07268.1 - 0.22 10.6 1.9 7.3 5.7 0.1 3.0 3 0 0 3 3 3 0 Mu-like prophage protein Com Zn_Tnp_IS1595 PF12760.2 EDO07268.1 - 1.1 9.0 6.5 1.1 9.1 0.6 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF1610 PF07754.6 EDO07268.1 - 1.2 9.2 8.5 3.6 7.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) Gar1 PF04410.9 EDO07269.1 - 6.2e-18 64.7 0.0 9.2e-18 64.1 0.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region G-patch PF01585.18 EDO07270.1 - 1.4e-13 50.3 3.6 2.3e-13 49.6 2.5 1.3 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 EDO07270.1 - 0.00098 18.7 0.0 0.0031 17.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07270.1 - 0.034 14.1 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) UPF0203 PF05254.7 EDO07271.1 - 0.082 12.7 0.8 4.4 7.2 0.1 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) TPR_12 PF13424.1 EDO07272.1 - 4.5e-09 36.1 0.0 8.7e-08 31.9 0.0 2.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO07272.1 - 3.3e-06 26.4 0.0 0.0011 18.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO07272.1 - 0.00072 19.0 0.0 0.027 14.0 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDO07272.1 - 0.0033 17.0 0.0 0.056 13.1 0.0 1.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDO07272.1 - 0.012 15.5 0.0 0.11 12.4 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat EIF_2_alpha PF07541.7 EDO07273.1 - 4.6e-31 106.8 0.0 9.2e-31 105.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EDO07273.1 - 2.6e-11 43.4 0.1 5.5e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 EDO07273.1 - 0.021 14.7 0.1 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 Sigma70_ner PF04546.8 EDO07273.1 - 4.3 6.9 7.4 13 5.3 2.0 2.6 2 1 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.8 EDO07273.1 - 8.5 4.0 9.2 12 3.5 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi SRP54 PF00448.17 EDO07275.1 - 7.2e-76 254.0 0.5 1.3e-75 253.2 0.4 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EDO07275.1 - 5.6e-25 87.6 0.1 5.6e-25 87.6 0.0 3.5 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.14 EDO07275.1 - 2.3e-13 50.0 2.4 2.3e-13 50.0 1.7 2.7 3 0 0 3 3 2 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EDO07275.1 - 3.2e-06 26.7 0.1 1e-05 25.0 0.1 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 EDO07275.1 - 4.5e-06 26.2 0.1 2.2e-05 23.9 0.1 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 EDO07275.1 - 3.6e-05 23.6 0.0 9.6e-05 22.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 EDO07275.1 - 4.2e-05 23.2 0.2 0.00023 20.8 0.0 2.4 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EDO07275.1 - 4.3e-05 23.6 0.9 0.00038 20.5 0.0 2.9 4 0 0 4 4 3 1 AAA domain ArgK PF03308.11 EDO07275.1 - 0.0002 20.2 0.1 0.00078 18.3 0.0 2.0 2 1 0 2 2 2 1 ArgK protein Zeta_toxin PF06414.7 EDO07275.1 - 0.00023 20.3 0.0 0.00043 19.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EDO07275.1 - 0.0023 18.7 0.0 0.0067 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EDO07275.1 - 0.0038 17.1 0.0 3.2 7.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDO07275.1 - 0.0055 16.7 0.5 0.19 11.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain APS_kinase PF01583.15 EDO07275.1 - 0.0065 16.1 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_10 PF12846.2 EDO07275.1 - 0.007 15.8 0.0 1.5 8.1 0.0 3.1 2 1 0 2 2 2 1 AAA-like domain XkdN PF08890.6 EDO07275.1 - 0.0076 15.9 0.3 0.029 14.1 0.0 2.1 2 0 0 2 2 1 1 Phage XkdN-like protein KaiC PF06745.8 EDO07275.1 - 0.008 15.3 0.1 0.008 15.3 0.0 2.6 4 0 0 4 4 4 1 KaiC SRPRB PF09439.5 EDO07275.1 - 0.0082 15.3 0.7 1.4 8.1 0.5 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ResIII PF04851.10 EDO07275.1 - 0.017 14.9 0.4 0.058 13.2 0.2 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2209 PF09974.4 EDO07275.1 - 0.028 14.5 0.5 0.13 12.3 0.2 2.2 3 0 0 3 3 1 0 Uncharacterized protein conserved in archaea (DUF2209) AAA_18 PF13238.1 EDO07275.1 - 0.036 14.3 0.1 0.19 12.0 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EDO07275.1 - 0.045 13.3 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EDO07275.1 - 0.052 12.9 0.3 0.36 10.1 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase Fe-ADH PF00465.14 EDO07275.1 - 0.067 11.8 0.2 0.19 10.3 0.0 1.8 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase VirE PF05272.6 EDO07275.1 - 0.069 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E PduV-EutP PF10662.4 EDO07275.1 - 0.069 12.6 2.1 2.3 7.7 0.0 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EDO07275.1 - 0.079 13.1 0.3 1.5 9.0 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDO07275.1 - 0.11 11.9 0.1 0.38 10.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDO07275.1 - 0.11 12.2 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 EDO07275.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EDO07275.1 - 0.25 10.4 1.6 3.3 6.8 0.0 2.9 3 1 0 3 3 3 0 Chromatin associated protein KTI12 DDE_Tnp_1_3 PF13612.1 EDO07275.1 - 0.73 9.5 3.7 1.1 8.9 0.2 2.4 2 0 0 2 2 2 0 Transposase DDE domain ArsA_ATPase PF02374.10 EDO07275.1 - 0.8 8.6 6.6 0.62 9.0 0.6 3.4 3 1 0 3 3 3 0 Anion-transporting ATPase KH_1 PF00013.24 EDO07276.1 - 8.1e-05 22.1 0.0 0.032 13.8 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 EDO07276.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 KH domain XPG_I PF00867.13 EDO07277.1 - 2.4e-11 43.5 1.8 3.5e-11 43.0 0.3 2.0 3 0 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.15 EDO07277.1 - 0.0004 20.5 0.0 0.00075 19.6 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 EDO07277.1 - 0.066 13.1 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif mTERF PF02536.9 EDO07278.1 - 2.6e-15 55.8 0.0 7.5e-13 47.7 0.0 2.3 2 0 0 2 2 2 2 mTERF Ufm1 PF03671.9 EDO07281.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein Syntaxin-6_N PF09177.6 EDO07282.1 - 8.6e-20 70.9 0.5 8.6e-20 70.9 0.4 1.8 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EDO07282.1 - 4.4e-06 26.2 4.0 4.4e-06 26.2 2.8 3.1 3 0 0 3 3 3 1 SNARE domain ArsR PF09824.4 EDO07282.1 - 0.0036 16.6 4.0 0.027 13.8 0.1 2.2 1 1 0 2 2 2 1 ArsR transcriptional regulator Sigma_1_2 PF03084.9 EDO07282.1 - 0.014 14.0 0.1 0.018 13.6 0.1 1.3 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family Cellulase-like PF12876.2 EDO07282.1 - 0.065 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like E2R135 PF11570.3 EDO07282.1 - 0.069 13.2 2.7 0.15 12.1 1.8 1.6 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 TBPIP PF07106.8 EDO07282.1 - 0.15 11.6 5.2 0.059 12.9 0.9 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 EDO07282.1 - 0.35 9.9 3.5 1.1 8.3 0.4 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 EDO07282.1 - 0.36 10.2 4.7 0.53 9.7 1.8 2.0 1 1 1 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.5 EDO07282.1 - 1.3 9.1 8.0 1.9 8.5 1.8 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AAA PF00004.24 EDO07283.1 - 6.5e-43 146.0 0.0 1.5e-42 144.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO07283.1 - 2.4e-07 30.9 0.1 6.8e-05 23.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EDO07283.1 - 3.6e-06 27.0 0.0 7.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EDO07283.1 - 4.8e-06 26.3 0.1 2.9e-05 23.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO07283.1 - 1.1e-05 25.5 0.0 2.9e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EDO07283.1 - 5e-05 22.4 0.0 0.0001 21.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EDO07283.1 - 5.2e-05 22.2 0.0 8.9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EDO07283.1 - 6.1e-05 22.5 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EDO07283.1 - 0.00025 21.8 0.0 0.00081 20.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EDO07283.1 - 0.00046 19.8 0.0 0.29 10.7 0.0 3.1 2 1 1 3 3 3 1 NACHT domain AAA_19 PF13245.1 EDO07283.1 - 0.00059 19.5 0.2 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EDO07283.1 - 0.0016 18.3 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO07283.1 - 0.0021 18.3 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EDO07283.1 - 0.003 17.7 0.0 0.0065 16.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 EDO07283.1 - 0.0031 17.4 0.3 0.006 16.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EDO07283.1 - 0.0043 16.9 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDO07283.1 - 0.0048 16.3 0.4 0.071 12.5 0.1 2.3 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 EDO07283.1 - 0.0093 14.7 0.0 0.019 13.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EDO07283.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EDO07283.1 - 0.015 14.9 0.2 0.033 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EDO07283.1 - 0.015 14.5 0.2 0.075 12.2 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.7 EDO07283.1 - 0.029 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EDO07283.1 - 0.055 13.5 0.0 0.18 11.8 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EDO07283.1 - 0.057 12.5 0.0 0.35 9.9 0.0 2.2 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.17 EDO07283.1 - 0.075 11.8 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_3 PF07726.6 EDO07283.1 - 0.099 12.2 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EDO07283.1 - 0.12 12.1 0.1 0.41 10.2 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase Parvo_NS1 PF01057.12 EDO07283.1 - 0.13 11.0 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EDO07283.1 - 0.15 11.4 0.1 1.2 8.5 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EDO07283.1 - 0.28 10.8 1.4 1.8 8.2 0.3 2.6 2 1 0 2 2 2 0 NTPase UQ_con PF00179.21 EDO07284.1 - 1.3e-17 63.5 0.0 2.7e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Nup54 PF13874.1 EDO07284.1 - 5.2e-11 42.3 0.4 1.2e-10 41.2 0.3 1.5 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 ATG16 PF08614.6 EDO07284.1 - 0.052 13.3 5.6 0.11 12.3 3.9 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PLU-1 PF08429.6 EDO07284.1 - 0.056 12.3 5.2 3.9 6.2 0.0 2.5 2 1 0 2 2 2 0 PLU-1-like protein CorA PF01544.13 EDO07284.1 - 0.13 11.2 2.4 0.13 11.3 0.3 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF445 PF04286.7 EDO07284.1 - 0.16 11.4 2.4 0.18 11.3 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Snf7 PF03357.16 EDO07284.1 - 0.22 10.9 5.2 0.083 12.2 1.3 1.9 2 0 0 2 2 2 0 Snf7 FAD_binding_2 PF00890.19 EDO07284.1 - 0.23 10.2 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Ly49 PF08391.5 EDO07284.1 - 1.3 9.1 4.9 1.7 8.7 0.4 2.7 3 0 0 3 3 3 0 Ly49-like protein, N-terminal region XRN_N PF03159.13 EDO07285.1 - 2.2e-55 187.6 0.1 3e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus CbiK PF06180.6 EDO07285.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Antifungal_prot PF11402.3 EDO07285.1 - 0.43 10.8 4.1 0.29 11.3 0.3 2.3 2 0 0 2 2 2 0 Antifungal protein Transglut_core PF01841.14 EDO07286.1 - 0.0074 16.4 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily FAD_binding_1 PF00667.15 EDO07289.1 - 8.4e-15 54.8 0.0 2.8e-14 53.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 EDO07289.1 - 5e-13 49.2 0.0 1.3e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EDO07289.1 - 0.077 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain zf-RING_UBOX PF13445.1 EDO07291.1 - 9.6e-13 47.6 5.0 2.2e-12 46.4 3.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EDO07291.1 - 7.3e-06 25.7 5.5 1.9e-05 24.4 3.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EDO07291.1 - 8.1e-05 22.4 5.1 0.00015 21.5 2.8 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EDO07291.1 - 0.00019 21.3 6.4 0.00048 20.1 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO07291.1 - 0.00021 20.9 4.5 0.00046 19.7 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO07291.1 - 0.00093 18.8 6.4 0.0022 17.5 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO07291.1 - 0.0012 18.5 8.1 0.0032 17.1 5.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-MIZ PF02891.15 EDO07291.1 - 0.2 11.2 6.0 0.55 9.7 4.2 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.1 EDO07291.1 - 2.3 7.8 7.4 2.5 7.6 3.6 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 AAA_6 PF12774.2 EDO07292.1 - 2.7e-47 161.2 0.1 6e-47 160.1 0.1 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 EDO07292.1 - 5.5e-33 114.0 10.6 5.5e-33 114.0 7.3 4.6 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 MT PF12777.2 EDO07292.1 - 3.3e-20 72.1 14.8 5e-20 71.5 9.1 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.10 EDO07292.1 - 1e-14 53.5 1.2 1e-14 53.5 0.8 2.0 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA PF00004.24 EDO07292.1 - 2.6e-06 27.6 0.1 0.18 12.0 0.0 4.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO07292.1 - 9.1e-06 25.4 0.0 0.12 12.1 0.0 4.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO07292.1 - 0.0037 17.2 0.0 1 9.3 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EDO07292.1 - 0.0048 16.4 0.0 0.87 9.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Neuromodulin_N PF10580.4 EDO07292.1 - 0.0099 15.5 1.8 0.023 14.3 1.2 1.6 1 0 0 1 1 1 1 Gap junction protein N-terminal region AAA_19 PF13245.1 EDO07292.1 - 0.13 12.0 0.0 6.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EDO07292.1 - 0.15 12.2 8.8 1.5 8.9 0.0 5.5 7 0 0 7 7 7 0 AAA domain AAA_17 PF13207.1 EDO07292.1 - 0.42 11.4 5.2 41 5.0 0.0 5.0 5 0 0 5 5 4 0 AAA domain Adaptin_N PF01602.15 EDO07294.1 - 1.2e-61 208.6 12.6 1.6e-61 208.2 8.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EDO07294.1 - 0.0049 17.1 0.0 0.02 15.1 0.0 2.1 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.17 EDO07294.1 - 0.9 9.7 3.2 2e+02 2.5 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat FtsJ PF01728.14 EDO07295.1 - 8.4e-59 198.5 0.2 1.1e-58 198.1 0.1 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase NinF PF05810.7 EDO07295.1 - 0.058 13.2 0.1 0.058 13.2 0.0 2.7 3 0 0 3 3 3 0 NinF protein Brix PF04427.13 EDO07296.1 - 7.4e-27 94.2 0.3 7.4e-27 94.2 0.2 1.5 2 0 0 2 2 2 1 Brix domain Bd3614_N PF14442.1 EDO07296.1 - 0.26 11.2 1.8 0.46 10.4 1.3 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal NMD3 PF04981.8 EDO07297.1 - 5.3e-61 205.7 15.6 9.9e-61 204.8 10.8 1.5 1 0 0 1 1 1 1 NMD3 family C1_1 PF00130.17 EDO07297.1 - 4.7 7.0 16.1 34 4.2 0.1 3.2 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SRP9-21 PF05486.7 EDO07298.1 - 6.9e-21 73.7 0.2 1e-20 73.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) RRM_6 PF14259.1 EDO07299.1 - 4.3e-12 45.8 0.0 1.4e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO07299.1 - 1.2e-08 34.4 0.2 1e-05 25.0 0.1 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07299.1 - 1.5e-07 31.1 0.1 0.0049 16.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Minor_capsid_2 PF11114.3 EDO07300.1 - 0.25 11.2 2.1 0.3 10.9 0.6 1.8 2 0 0 2 2 2 0 Minor capsid protein RabGAP-TBC PF00566.13 EDO07301.1 - 3.4e-11 43.0 1.3 4.2e-11 42.7 0.2 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 EDO07301.1 - 6.8e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.20 EDO07302.1 - 2.2e-13 49.9 0.6 7.4e-13 48.2 0.4 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO07302.1 - 1.2e-08 34.3 0.0 2.7e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO07302.1 - 0.021 13.7 0.0 0.23 10.4 0.0 2.1 1 1 0 1 1 1 0 Kinase-like SspK PF08176.7 EDO07303.1 - 0.024 14.6 0.1 11 6.0 0.0 3.3 3 0 0 3 3 3 0 Small acid-soluble spore protein K family DEAD PF00270.24 EDO07304.1 - 6.9e-39 133.0 0.1 1.1e-38 132.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO07304.1 - 7.5e-20 70.5 0.0 1.5e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EDO07304.1 - 1.8e-15 56.2 0.1 4.3e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EDO07304.1 - 4.7e-05 23.2 0.0 0.00011 22.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EDO07304.1 - 0.48 9.4 4.6 1.9 7.4 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Nse4_C PF08743.5 EDO07305.1 - 5.9e-21 74.2 0.1 2e-20 72.5 0.0 1.9 2 0 0 2 2 2 1 Nse4 C-terminal PI3_PI4_kinase PF00454.22 EDO07306.1 - 1.3e-31 109.8 0.3 1.1e-29 103.6 0.0 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EDO07306.1 - 2.8e-09 36.4 0.5 5.9e-09 35.3 0.4 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) tRNA-synt_2 PF00152.15 EDO07307.1 - 1.5e-56 191.6 0.0 4.4e-56 190.0 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EDO07307.1 - 0.00032 19.9 0.0 0.021 14.0 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Pro_isomerase PF00160.16 EDO07309.1 - 9e-49 165.6 0.1 1.8e-48 164.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EDO07309.1 - 3.5e-06 26.6 0.2 0.016 15.1 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-CCCH PF00642.19 EDO07310.1 - 0.0034 17.0 0.3 0.0034 17.0 0.2 4.4 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF285 PF03382.9 EDO07310.1 - 0.02 14.4 0.2 0.046 13.2 0.1 1.6 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 Mu-like_Pro PF10123.4 EDO07310.1 - 0.074 12.4 0.1 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein AATF-Che1 PF13339.1 EDO07310.1 - 0.39 10.8 2.4 0.71 10.0 0.0 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor zf-CCCH PF00642.19 EDO07311.1 - 3.6e-09 36.0 2.3 6.7e-09 35.2 1.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 EDO07311.1 - 6.5e-06 25.7 7.4 1.2e-05 24.8 5.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDO07311.1 - 1.1e-05 24.9 6.6 2.1e-05 24.0 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO07311.1 - 0.0001 21.8 9.3 0.00022 20.8 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO07311.1 - 0.00022 20.9 6.7 0.0004 20.1 4.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDO07311.1 - 0.00037 20.4 9.4 0.00072 19.5 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ebp2 PF05890.7 EDO07311.1 - 0.013 14.8 5.6 0.013 14.8 3.9 1.4 2 0 0 2 2 2 0 Eukaryotic rRNA processing protein EBP2 Siah-Interact_N PF09032.6 EDO07311.1 - 0.062 13.3 4.7 0.17 11.9 3.2 1.8 1 0 0 1 1 1 0 Siah interacting protein, N terminal RP-C_C PF11800.3 EDO07311.1 - 0.08 12.6 2.1 0.14 11.7 1.5 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region zf-RING_UBOX PF13445.1 EDO07311.1 - 0.087 12.5 3.9 0.2 11.4 2.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EDO07311.1 - 0.49 10.3 8.6 2.4 8.1 6.0 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING CDC45 PF02724.9 EDO07311.1 - 0.64 7.9 8.5 0.15 10.0 3.4 1.6 2 0 0 2 2 2 0 CDC45-like protein Ndc1_Nup PF09531.5 EDO07311.1 - 1.1 7.5 3.7 1.6 7.0 2.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NARP1 PF12569.3 EDO07311.1 - 2 7.0 7.6 3.1 6.4 5.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CoaE PF01121.15 EDO07312.1 - 5.5e-40 136.6 0.1 3.5e-39 134.0 0.1 1.9 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 EDO07312.1 - 1.9e-08 34.6 0.3 4.1e-07 30.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO07312.1 - 2.2e-08 34.9 0.1 3.4e-08 34.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDO07312.1 - 7.3e-06 25.9 0.0 0.00051 19.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EDO07312.1 - 0.00037 20.4 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO07312.1 - 0.013 15.2 0.1 0.058 13.1 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain SKI PF01202.17 EDO07312.1 - 0.015 15.1 0.1 0.3 10.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.1 EDO07312.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EDO07312.1 - 0.021 15.1 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Cytidylate_kin2 PF13189.1 EDO07312.1 - 0.029 14.2 0.1 4.3 7.1 0.1 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_16 PF13191.1 EDO07312.1 - 0.039 13.9 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_2 PF03668.10 EDO07312.1 - 0.065 12.3 0.2 0.14 11.2 0.1 1.5 2 0 0 2 2 2 0 P-loop ATPase protein family ArfGap PF01412.13 EDO07313.1 - 2.2e-31 108.0 1.8 3.4e-31 107.4 0.0 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf RNA_pol_Rpb1_5 PF04998.12 EDO07314.1 - 4.9e-85 285.1 0.0 1.5e-84 283.5 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EDO07314.1 - 8.5e-56 188.4 0.0 1.7e-55 187.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EDO07314.1 - 1.9e-27 95.9 0.0 6.7e-27 94.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EDO07314.1 - 4.8e-15 55.2 0.1 1.2e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 EDO07314.1 - 4.5e-14 52.4 1.0 1.8e-10 40.5 0.1 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 1 Nop14 PF04147.7 EDO07314.1 - 2.4 5.9 12.4 3.8 5.3 8.6 1.2 1 0 0 1 1 1 0 Nop14-like family Ufd2P_core PF10408.4 EDO07315.1 - 4.5e-122 408.4 24.3 5.9e-122 408.0 16.8 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EDO07315.1 - 3.4e-24 84.5 1.2 9.3e-24 83.1 0.8 1.8 1 0 0 1 1 1 1 U-box domain Phe_tRNA-synt_N PF02912.13 EDO07315.1 - 0.065 12.9 0.1 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain LSM PF01423.17 EDO07317.1 - 6.3e-20 70.5 0.1 7e-20 70.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain SNF2_N PF00176.18 EDO07318.1 - 2.2e-58 197.4 0.0 3.5e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO07318.1 - 8.2e-13 48.0 0.0 1.8e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO07318.1 - 4.7e-08 33.0 0.8 1.3e-07 31.6 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDO07318.1 - 6.4e-08 32.2 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EDO07318.1 - 0.018 14.0 0.0 0.049 12.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EDO07318.1 - 0.13 12.4 0.0 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain UQ_con PF00179.21 EDO07319.1 - 5.9e-37 126.2 0.1 7.9e-37 125.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Asp PF00026.18 EDO07320.1 - 9.9e-38 130.1 1.2 2.7e-36 125.4 0.8 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDO07320.1 - 0.054 13.9 0.1 0.83 10.1 0.0 2.8 2 1 0 2 2 2 0 Aspartyl protease Ribosomal_L1 PF00687.16 EDO07321.1 - 8.8e-47 159.2 0.5 1.4e-46 158.6 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family FAST_1 PF06743.10 EDO07322.1 - 0.00081 19.0 3.5 1.6 8.5 0.0 4.4 3 1 0 3 3 3 2 FAST kinase-like protein, subdomain 1 zf-Tim10_DDP PF02953.10 EDO07323.1 - 3.9e-18 64.5 2.7 5.1e-18 64.1 1.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Antimicrobial17 PF08129.6 EDO07324.1 - 0.023 14.4 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta enterocin family G-patch PF01585.18 EDO07325.1 - 9.6e-15 54.1 2.0 1.9e-14 53.1 1.4 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EDO07325.1 - 3.4e-06 26.8 0.4 3.4e-06 26.8 0.3 2.4 2 1 1 3 3 3 1 DExH-box splicing factor binding site RNA_pol_Rpc82 PF05645.8 EDO07325.1 - 0.063 12.8 3.4 0.086 12.3 2.3 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 DUF1754 PF08555.5 EDO07325.1 - 1.2 9.7 12.9 2.5 8.7 9.0 1.5 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) PRP1_N PF06424.7 EDO07326.1 - 1.1e-41 142.2 5.1 1.4e-35 122.5 0.2 2.7 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EDO07326.1 - 1.1e-24 84.6 28.0 0.13 12.9 0.1 15.1 7 4 10 17 17 17 7 Tetratricopeptide repeat TPR_19 PF14559.1 EDO07326.1 - 1e-18 67.3 11.4 0.12 12.7 0.0 9.6 6 3 3 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 EDO07326.1 - 6.1e-09 35.4 14.2 0.16 11.6 0.0 8.8 7 3 2 10 10 10 3 TPR repeat TPR_17 PF13431.1 EDO07326.1 - 4.7e-07 29.5 1.9 0.39 11.0 0.0 7.6 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO07326.1 - 8.4e-07 29.5 20.0 0.82 10.4 0.0 8.8 9 2 1 10 10 10 2 Tetratricopeptide repeat Suf PF05843.9 EDO07326.1 - 2.8e-05 23.9 0.3 5.6 6.6 0.0 5.6 6 1 0 6 6 6 1 Suppressor of forked protein (Suf) TPR_2 PF07719.12 EDO07326.1 - 5.7e-05 22.7 13.5 0.48 10.4 0.0 8.6 10 0 0 10 10 9 2 Tetratricopeptide repeat DUF3808 PF10300.4 EDO07326.1 - 0.00014 20.5 0.6 0.14 10.7 0.0 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF3808) TPR_7 PF13176.1 EDO07326.1 - 0.017 14.8 1.8 2.2 8.2 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO07326.1 - 0.027 14.0 4.2 0.3 10.7 0.0 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO07326.1 - 0.037 13.9 13.4 11 5.9 0.0 7.3 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.4 EDO07326.1 - 0.41 10.5 7.4 0.53 10.2 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EDO07326.1 - 3.7 7.4 8.6 3.1 7.7 0.1 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat CC2D2AN-C2 PF15625.1 EDO07327.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain Vps35 PF03635.12 EDO07328.1 - 3.5e-170 567.7 11.6 4.3e-170 567.4 8.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Glutaminase PF04960.10 EDO07328.1 - 0.16 10.9 1.3 0.28 10.1 0.9 1.3 1 0 0 1 1 1 0 Glutaminase DUF3811 PF11656.3 EDO07329.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 YjbD family (DUF3811) Pro_isomerase PF00160.16 EDO07330.1 - 0.078 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1281 PF06924.6 EDO07330.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) Nol1_Nop2_Fmu PF01189.12 EDO07331.1 - 0.0045 16.3 0.0 0.017 14.5 0.0 1.9 2 0 0 2 2 2 1 NOL1/NOP2/sun family Es2 PF09751.4 EDO07332.1 - 1.7e-48 166.0 11.1 5.2e-27 95.3 2.0 3.3 1 1 2 3 3 3 3 Nuclear protein Es2 Actin PF00022.14 EDO07333.1 - 1e-71 241.5 0.0 1.2e-71 241.2 0.0 1.0 1 0 0 1 1 1 1 Actin Ribosomal_L11 PF00298.14 EDO07334.1 - 2.2e-20 72.5 0.0 3.3e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EDO07334.1 - 4.3e-19 67.7 0.0 2e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Gcd10p PF04189.8 EDO07335.1 - 8.1e-56 189.3 0.1 1.2e-55 188.7 0.1 1.2 1 0 0 1 1 1 1 Gcd10p family RICTOR_phospho PF14665.1 EDO07335.1 - 0.07 13.2 0.3 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site SPOB_a PF14689.1 EDO07335.1 - 0.11 12.1 0.2 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain DUF2762 PF10960.3 EDO07335.1 - 0.13 12.0 1.8 0.35 10.6 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) PROL5-SMR PF15621.1 EDO07336.1 - 5.7 7.4 8.2 1.6 9.2 3.2 1.9 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family DUF2465 PF10239.4 EDO07338.1 - 0.002 17.3 3.1 0.0026 17.0 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) PMM PF03332.8 EDO07339.1 - 6e-98 326.7 0.8 6.9e-98 326.5 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EDO07339.1 - 1.2e-12 47.9 0.3 3.7e-12 46.3 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EDO07339.1 - 1.6e-05 24.3 0.0 0.0011 18.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EDO07339.1 - 0.025 15.0 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 EDO07339.1 - 0.03 13.2 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Trehalose-phosphatase HAD PF12710.2 EDO07339.1 - 0.13 12.4 2.0 2.2 8.4 1.3 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RAP-1 PF03085.10 EDO07340.1 - 4.4e-106 353.8 4.0 8.4e-106 352.9 2.8 1.5 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) DUF4325 PF14213.1 EDO07340.1 - 0.00041 19.9 0.4 16 5.2 0.1 4.7 2 1 2 4 4 4 1 Domain of unknown function (DUF4325) PHA_synth_III_E PF09712.5 EDO07340.1 - 0.0021 17.5 2.3 2 7.7 0.1 3.1 1 1 2 3 3 3 3 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) REF PF05755.7 EDO07340.1 - 0.016 14.9 0.7 0.56 9.9 0.2 2.7 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) Foie-gras_1 PF11817.3 EDO07340.1 - 0.052 13.0 0.1 0.095 12.1 0.1 1.4 1 0 0 1 1 1 0 Foie gras liver health family 1 FliP PF00813.15 EDO07340.1 - 0.2 11.3 4.8 3.2 7.4 0.2 3.3 1 1 3 4 4 4 0 FliP family RAP-1 PF03085.10 EDO07341.1 - 4.4e-106 353.8 4.0 8.4e-106 352.9 2.8 1.5 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) DUF4325 PF14213.1 EDO07341.1 - 0.00041 19.9 0.4 16 5.2 0.1 4.7 2 1 2 4 4 4 1 Domain of unknown function (DUF4325) PHA_synth_III_E PF09712.5 EDO07341.1 - 0.0021 17.5 2.3 2 7.7 0.1 3.1 1 1 2 3 3 3 3 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) REF PF05755.7 EDO07341.1 - 0.016 14.9 0.7 0.56 9.9 0.2 2.7 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) Foie-gras_1 PF11817.3 EDO07341.1 - 0.052 13.0 0.1 0.095 12.1 0.1 1.4 1 0 0 1 1 1 0 Foie gras liver health family 1 FliP PF00813.15 EDO07341.1 - 0.2 11.3 4.8 3.2 7.4 0.2 3.3 1 1 3 4 4 4 0 FliP family HEAT_2 PF13646.1 EDO07342.1 - 4.1e-26 91.0 8.4 2.2e-16 59.8 0.3 2.7 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 EDO07342.1 - 1.2e-17 62.4 8.5 0.0026 18.0 0.0 6.3 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EDO07342.1 - 5.4e-07 29.9 0.4 0.042 14.3 0.0 3.6 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.17 EDO07342.1 - 9.3e-05 22.2 1.8 0.026 14.5 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 EDO07342.1 - 0.024 14.4 0.5 0.79 9.6 0.0 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DnaJ PF00226.26 EDO07343.1 - 1.2e-26 92.2 0.4 2.2e-26 91.3 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EDO07343.1 - 1.2e-19 70.0 0.1 2e-18 66.0 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EDO07343.1 - 1.4e-14 53.8 15.3 2.5e-14 53.0 10.6 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EDO07343.1 - 0.12 12.0 7.5 3 7.5 2.2 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family eIF2A PF08662.6 EDO07344.1 - 2.9e-57 193.5 0.0 3e-56 190.2 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A FHA PF00498.21 EDO07345.1 - 0.00014 21.8 0.0 0.0004 20.4 0.0 1.8 1 0 0 1 1 1 1 FHA domain Cmyb_C PF09316.5 EDO07345.1 - 0.013 15.1 0.1 0.069 12.8 0.0 2.0 2 0 0 2 2 2 0 C-myb, C-terminal PC_rep PF01851.17 EDO07346.1 - 2.3e-11 43.2 21.0 0.0039 17.3 0.1 8.3 9 0 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EDO07346.1 - 0.048 13.9 2.6 3.2 8.1 0.0 3.4 3 1 1 4 4 4 0 HEAT repeats AAA PF00004.24 EDO07348.1 - 2.5e-42 144.2 0.0 1e-41 142.2 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO07348.1 - 5.5e-07 29.7 0.1 5.4e-05 23.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDO07348.1 - 1.5e-06 27.9 0.0 5.4e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO07348.1 - 9.7e-05 22.4 0.1 0.00023 21.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EDO07348.1 - 0.00018 21.4 0.0 0.00035 20.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EDO07348.1 - 0.0002 22.1 0.1 0.00038 21.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO07348.1 - 0.00098 18.8 0.1 0.0021 17.7 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EDO07348.1 - 0.0012 17.9 0.0 0.0025 16.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EDO07348.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EDO07348.1 - 0.016 15.1 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDO07348.1 - 0.017 15.3 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EDO07348.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EDO07348.1 - 0.02 13.8 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EDO07348.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EDO07348.1 - 0.037 13.6 0.1 0.086 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EDO07348.1 - 0.043 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EDO07348.1 - 0.044 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 EDO07348.1 - 0.053 12.2 0.0 0.098 11.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Histone PF00125.19 EDO07348.1 - 0.059 13.4 0.5 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 NB-ARC PF00931.17 EDO07348.1 - 0.064 12.1 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 EDO07348.1 - 0.077 12.0 0.0 1.1 8.3 0.0 2.6 3 0 0 3 3 3 0 KaiC RNA_helicase PF00910.17 EDO07348.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 EDO07348.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDO07348.1 - 0.13 11.6 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EDO07348.1 - 0.13 11.7 0.0 0.51 9.7 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EDO07348.1 - 0.16 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Adap_comp_sub PF00928.16 EDO07349.1 - 2.5e-81 272.6 0.1 3e-81 272.3 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EDO07349.1 - 1.8e-09 37.4 1.1 3.3e-09 36.5 0.8 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain VirB8 PF04335.8 EDO07349.1 - 0.016 14.8 0.1 0.026 14.0 0.1 1.2 1 0 0 1 1 1 0 VirB8 protein Intron_maturas2 PF01348.16 EDO07350.1 - 0.05 13.5 0.3 0.05 13.5 0.2 2.1 2 1 0 2 2 2 0 Type II intron maturase TPT PF03151.11 EDO07351.1 - 2e-19 69.7 6.2 2e-19 69.7 4.3 2.2 1 1 1 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EDO07351.1 - 1.3e-06 28.4 22.9 5.6e-05 23.1 6.1 3.2 3 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EDO07351.1 - 0.0043 17.2 15.2 0.048 13.8 3.2 2.7 3 0 0 3 3 3 2 Multidrug resistance efflux transporter UAA PF08449.6 EDO07351.1 - 0.96 8.2 14.6 18 4.1 10.1 2.3 1 1 0 1 1 1 0 UAA transporter family Ribosomal_S16 PF00886.14 EDO07352.1 - 4.8e-09 35.7 0.0 1.5e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S16 GCFC PF07842.7 EDO07353.1 - 3.3e-10 39.7 1.7 3.3e-10 39.7 1.2 1.8 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EDO07353.1 - 5.9e-10 38.7 5.8 1.5e-09 37.4 4.0 1.7 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.3 EDO07353.1 - 0.0055 16.7 3.4 0.015 15.3 2.3 1.7 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal DUF1110 PF06533.7 EDO07353.1 - 0.04 13.7 0.5 9 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1110) G-patch_2 PF12656.2 EDO07353.1 - 0.11 12.3 1.3 0.35 10.7 0.9 1.8 1 0 0 1 1 1 0 DExH-box splicing factor binding site PFEMP PF03011.10 EDO07355.1 - 1.6 9.0 7.9 1.1 9.6 3.7 2.0 1 1 1 2 2 2 0 PFEMP DBL domain E1-E2_ATPase PF00122.15 EDO07356.1 - 1.1e-62 211.0 8.3 1.1e-62 211.0 5.7 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDO07356.1 - 1.9e-34 118.8 1.6 7.7e-34 116.8 0.0 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDO07356.1 - 1.8e-26 93.9 0.0 9.5e-25 88.2 0.0 3.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDO07356.1 - 7.3e-18 63.7 0.0 1.5e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EDO07356.1 - 2e-12 47.7 0.0 5.4e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDO07356.1 - 2.1e-12 46.8 0.0 7.8e-12 44.9 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDO07356.1 - 0.00013 21.6 1.0 0.00033 20.3 0.5 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ubiquitin PF00240.18 EDO07357.1 - 3.5e-106 346.6 11.8 8.3e-35 118.0 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 EDO07357.1 - 9.2e-62 204.6 10.9 7.1e-20 70.4 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDO07357.1 - 1.8e-21 76.1 3.6 2.5e-05 24.4 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDO07357.1 - 1.3e-16 60.6 0.1 0.00015 21.5 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDO07357.1 - 1.4e-11 44.2 0.8 0.05 13.4 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDO07357.1 - 5.7e-10 39.2 0.2 0.14 12.3 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EDO07357.1 - 5.3e-09 35.8 1.1 0.25 11.2 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF2870 PF11069.3 EDO07357.1 - 6.1e-08 32.5 0.0 1 9.4 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EDO07357.1 - 8.5e-06 25.4 0.6 3.7 7.3 0.0 3.3 3 0 0 3 3 3 3 FlgD Ig-like domain USP7_C2 PF14533.1 EDO07357.1 - 9.2e-05 21.9 1.7 4.2 6.7 0.0 3.1 1 1 0 3 3 3 3 Ubiquitin-specific protease C-terminal Phage_pRha PF09669.5 EDO07357.1 - 0.002 18.4 0.1 8.1 6.8 0.0 3.2 3 0 0 3 3 3 0 Phage regulatory protein Rha (Phage_pRha) CTDII PF01556.13 EDO07357.1 - 0.0024 17.7 8.8 1.9 8.4 0.2 3.3 1 1 1 3 3 3 2 DnaJ C terminal domain Plexin_cytopl PF08337.7 EDO07357.1 - 0.003 15.9 5.5 3.9 5.6 0.1 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain FERM_N PF09379.5 EDO07357.1 - 0.0032 17.4 3.4 27 4.8 0.1 4.7 3 3 0 3 3 3 0 FERM N-terminal domain GABP-alpha PF11620.3 EDO07357.1 - 0.012 15.5 0.8 39 4.3 0.0 3.0 3 0 0 3 3 3 0 GA-binding protein alpha chain CpeS PF09367.5 EDO07357.1 - 0.015 15.2 0.1 27 4.5 0.0 3.0 3 0 0 3 3 3 0 CpeS-like protein YfmQ PF10787.4 EDO07357.1 - 0.016 14.5 0.2 34 3.7 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein from bacillus cereus group EMG1 PF03587.9 EDO07357.1 - 0.018 14.3 0.1 13 4.9 0.0 3.1 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase DUF3781 PF12636.2 EDO07357.1 - 0.35 10.8 1.9 1.1e+02 2.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) YajC PF02699.10 EDO07357.1 - 0.65 9.7 4.1 38 4.0 0.0 3.1 3 0 0 3 3 3 0 Preprotein translocase subunit Sec_GG PF07549.9 EDO07357.1 - 5 6.5 8.3 1.8e+02 1.6 0.0 5.3 6 0 0 6 6 6 0 SecD/SecF GG Motif MCM PF00493.18 EDO07358.1 - 1.5e-128 428.2 1.2 2.3e-128 427.6 0.9 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDO07358.1 - 1.1e-07 32.3 2.0 1.6e-07 31.8 0.2 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDO07358.1 - 2.5e-07 30.0 0.0 2.4e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDO07358.1 - 0.012 15.3 0.0 0.047 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) zf-Di19 PF05605.7 EDO07358.1 - 0.014 15.4 0.4 0.082 13.0 0.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding AAA_3 PF07726.6 EDO07358.1 - 0.016 14.7 0.0 0.046 13.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDO07358.1 - 0.021 14.3 0.0 0.07 12.5 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain Amino_oxidase PF01593.19 EDO07359.1 - 7.7e-50 170.2 0.0 6.3e-36 124.4 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EDO07359.1 - 3.8e-12 46.0 0.1 1.1e-11 44.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDO07359.1 - 6.8e-07 28.6 0.1 2.1e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EDO07359.1 - 6.9e-06 25.1 3.3 1.6e-05 24.0 1.9 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDO07359.1 - 6.1e-05 23.1 0.1 0.00058 19.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDO07359.1 - 0.00014 20.8 2.3 0.0002 20.3 1.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EDO07359.1 - 0.00022 21.1 0.2 0.00073 19.4 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO07359.1 - 0.00023 21.4 0.2 0.00069 19.9 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EDO07359.1 - 0.00028 19.8 0.4 0.00052 18.9 0.3 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EDO07359.1 - 0.00037 19.7 1.6 0.00078 18.6 1.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EDO07359.1 - 0.00041 19.4 1.6 0.00071 18.7 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain zf-HC5HC2H PF13771.1 EDO07359.1 - 0.013 15.6 0.5 0.033 14.3 0.3 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain HI0933_like PF03486.9 EDO07359.1 - 0.021 13.3 1.0 0.035 12.5 0.7 1.3 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EDO07359.1 - 0.031 13.8 0.6 0.065 12.7 0.4 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EDO07359.1 - 0.13 12.3 0.0 0.52 10.4 0.0 2.0 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EDO07359.1 - 0.22 10.3 0.3 0.41 9.5 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.16 EDO07359.1 - 0.31 10.8 1.9 0.82 9.4 1.3 1.7 1 0 0 1 1 1 0 ThiF family DnaJ PF00226.26 EDO07360.1 - 5.6e-28 96.4 0.7 5.6e-28 96.4 0.5 1.9 3 0 0 3 3 3 1 DnaJ domain RPT PF13446.1 EDO07360.1 - 0.13 11.6 0.0 0.38 10.1 0.0 1.7 1 1 1 2 2 2 0 A repeated domain in UCH-protein PDEase_I PF00233.14 EDO07361.1 - 5.9e-48 163.6 0.4 9.6e-48 162.9 0.3 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ribosomal_S18 PF01084.15 EDO07362.1 - 7.9e-18 64.0 0.2 7.9e-18 64.0 0.1 2.8 3 0 0 3 3 3 1 Ribosomal protein S18 GRAM PF02893.15 EDO07363.1 - 3.6e-08 32.8 0.1 9.9e-08 31.4 0.0 1.8 1 0 0 1 1 1 1 GRAM domain bPH_6 PF10756.4 EDO07363.1 - 0.0075 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial PH domain Methyltransf_15 PF09445.5 EDO07364.1 - 1.2e-19 70.4 0.3 2.3e-19 69.5 0.2 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RNA_GG_bind PF10258.4 EDO07364.1 - 1.5e-10 40.6 0.0 2.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 PHAX RNA-binding domain Methyltransf_26 PF13659.1 EDO07364.1 - 8.2e-06 25.8 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO07364.1 - 0.00054 20.5 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO07364.1 - 0.0079 15.7 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Adap_comp_sub PF00928.16 EDO07365.1 - 2.7e-34 118.4 1.9 9e-34 116.7 1.3 1.7 1 1 0 1 1 1 1 Adaptor complexes medium subunit family GDPD PF03009.12 EDO07366.1 - 2.2e-17 63.4 0.0 1.6e-13 50.7 0.0 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Dynamin_N PF00350.18 EDO07367.1 - 6.8e-13 48.7 0.0 2.7e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 Dynamin family Dickkopf_N PF04706.7 EDO07367.1 - 3.6 7.8 8.0 6.6 6.9 5.6 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region adh_short PF00106.20 EDO07368.1 - 7.8e-12 45.4 0.0 5e-11 42.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 EDO07368.1 - 0.00013 21.2 0.0 0.00019 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EDO07368.1 - 0.18 11.4 0.0 0.41 10.2 0.0 1.8 1 1 0 1 1 1 0 KR domain Nrap PF03813.9 EDO07370.1 - 1.7e-69 234.4 0.6 1e-68 231.8 0.4 2.1 1 1 0 1 1 1 1 Nrap protein zf-RING_2 PF13639.1 EDO07372.1 - 6.3e-13 48.3 10.1 6.3e-13 48.3 7.0 2.5 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EDO07372.1 - 7.4e-10 38.8 5.2 1.9e-09 37.4 3.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EDO07372.1 - 2.6e-07 30.1 5.8 2.6e-07 30.1 4.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO07372.1 - 3.4e-06 26.6 9.6 6.9e-06 25.6 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO07372.1 - 3.8e-06 26.8 10.4 1e-05 25.4 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO07372.1 - 0.00027 20.5 9.5 0.00027 20.5 6.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EDO07372.1 - 0.0017 18.1 4.8 0.0038 17.0 3.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EDO07372.1 - 0.23 11.3 8.4 0.5 10.2 5.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EDO07372.1 - 0.3 11.0 8.0 1.9 8.5 5.6 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Rad50_zn_hook PF04423.9 EDO07372.1 - 0.48 9.9 4.6 8.7 5.9 0.6 3.1 2 0 0 2 2 2 0 Rad50 zinc hook motif Endonuclease_7 PF02945.10 EDO07372.1 - 7.1 6.4 8.1 2.8 7.7 0.2 2.5 1 1 1 2 2 2 0 Recombination endonuclease VII zf-RING_4 PF14570.1 EDO07372.1 - 9.3 5.9 11.4 2.6 7.7 5.2 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_L1 PF00687.16 EDO07373.1 - 3.7e-14 52.6 0.1 8e-14 51.5 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family MRL1 PF13003.2 EDO07373.1 - 3.9e-05 23.4 0.0 8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L1 Peptidase_M3_N PF08439.5 EDO07373.1 - 0.045 13.7 0.2 0.85 9.6 0.1 2.6 3 0 0 3 3 3 0 Oligopeptidase F Ribosomal_S25 PF03297.10 EDO07374.1 - 4e-35 120.0 9.0 4.4e-35 119.8 6.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Rrf2 PF02082.15 EDO07374.1 - 0.011 15.7 0.1 0.02 14.9 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator GntR PF00392.16 EDO07374.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DDRGK PF09756.4 EDO07374.1 - 0.035 13.5 1.0 0.054 12.8 0.7 1.3 1 1 0 1 1 1 0 DDRGK domain DUF3516 PF12029.3 EDO07374.1 - 0.06 12.1 1.9 0.063 12.0 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) RNA_pol_Rpc34 PF05158.7 EDO07374.1 - 0.068 12.3 0.4 0.11 11.6 0.1 1.3 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit DUF1667 PF07892.6 EDO07374.1 - 0.13 11.9 1.6 3.1 7.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1667) CRAL_TRIO PF00650.15 EDO07376.1 - 0.011 15.1 0.5 0.064 12.7 0.0 2.4 2 0 0 2 2 2 0 CRAL/TRIO domain Cu_amine_oxidN3 PF02728.11 EDO07376.1 - 0.042 13.9 0.0 0.16 12.0 0.0 2.0 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain E7 PF00527.13 EDO07376.1 - 0.15 12.2 1.4 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 E7 protein, Early protein DUF4094 PF13334.1 EDO07376.1 - 0.27 11.6 3.7 3 8.2 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) Pkinase PF00069.20 EDO07377.1 - 2.5e-62 210.3 0.0 3.1e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO07377.1 - 9.3e-32 110.1 0.1 1.7e-31 109.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EDO07377.1 - 0.00075 18.9 0.1 0.0013 18.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EDO07377.1 - 0.0018 18.0 0.0 0.037 13.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDO07377.1 - 0.007 15.3 0.0 0.014 14.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDO07377.1 - 0.014 14.4 0.2 0.041 12.9 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPRY PF00622.23 EDO07379.1 - 1.6e-14 54.0 0.7 2.8e-14 53.2 0.5 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 EDO07379.1 - 3.1e-12 46.4 0.6 4.9e-12 45.7 0.4 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-AD PF07776.10 EDO07380.1 - 0.018 15.0 0.8 0.74 9.8 0.1 2.2 1 1 1 2 2 2 0 Zinc-finger associated domain (zf-AD) Ssl1 PF04056.9 EDO07380.1 - 0.042 13.4 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 Ssl1-like MHCassoc_trimer PF08831.5 EDO07380.1 - 0.069 13.0 0.4 0.2 11.5 0.1 1.9 1 1 1 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Elf1 PF05129.8 EDO07380.1 - 0.12 12.1 3.3 0.26 11.0 2.3 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Ank_2 PF12796.2 EDO07381.1 - 2e-24 85.7 1.8 5.9e-14 52.1 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Bromodomain PF00439.20 EDO07381.1 - 3.7e-19 68.4 0.1 7.7e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Ank_4 PF13637.1 EDO07381.1 - 6.3e-18 64.7 2.5 8.6e-08 32.5 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EDO07381.1 - 1.4e-17 62.4 2.5 2.6e-06 26.9 0.1 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EDO07381.1 - 3.4e-14 51.5 1.2 0.0026 17.8 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EDO07381.1 - 2.1e-10 40.5 7.0 1.4e-06 28.3 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) RAP-1 PF03085.10 EDO07382.1 - 1.2e-83 280.2 8.7 1.5e-83 279.9 6.0 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) DUF3511 PF12023.3 EDO07382.1 - 0.0058 15.9 0.6 0.019 14.2 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3511) PP28 PF10252.4 EDO07383.1 - 6.9e-21 74.0 19.3 2.8e-20 72.1 13.4 2.1 1 1 0 1 1 1 1 Casein kinase substrate phosphoprotein PP28 AMA-1 PF02430.10 EDO07383.1 - 0.063 12.1 0.5 0.072 11.9 0.3 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 Trypan_PARP PF05887.6 EDO07383.1 - 1.7 8.4 6.2 2.2 8.0 4.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.9 EDO07383.1 - 6.8 4.5 14.6 7.2 4.5 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2407 PF10302.4 EDO07383.1 - 7.4 6.8 7.7 0.38 10.9 0.8 2.0 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain SNARE PF05739.14 EDO07384.1 - 7.2e-05 22.4 3.3 7.6e-05 22.3 0.9 2.1 2 0 0 2 2 2 1 SNARE domain DUF2365 PF10157.4 EDO07384.1 - 0.02 14.7 2.1 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) NPV_P10 PF05531.7 EDO07384.1 - 0.14 12.4 3.2 0.42 10.8 0.6 2.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein eIF-5a PF01287.15 EDO07384.1 - 0.22 11.5 1.3 28 4.7 0.0 3.1 3 0 0 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold FliJ PF02050.11 EDO07384.1 - 0.5 10.4 6.0 1.2 9.1 0.4 3.0 2 1 0 3 3 3 0 Flagellar FliJ protein Allexi_40kDa PF05549.6 EDO07384.1 - 0.66 9.2 10.1 0.28 10.4 1.2 2.1 1 1 0 2 2 2 0 Allexivirus 40kDa protein GAS PF13851.1 EDO07384.1 - 1.3 8.1 13.2 0.28 10.3 6.7 1.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding AATF-Che1 PF13339.1 EDO07384.1 - 2.4 8.3 5.6 0.9 9.6 1.0 2.0 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor FlaC_arch PF05377.6 EDO07384.1 - 6.2 6.7 9.5 12 5.8 0.1 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Helicase_C PF00271.26 EDO07385.1 - 1.1e-10 41.1 0.2 3.5e-10 39.5 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 EDO07385.1 - 3.4e-05 23.8 0.0 0.0001 22.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 EDO07385.1 - 0.00074 19.0 0.1 0.01 15.3 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDO07385.1 - 0.0013 18.8 0.0 0.0037 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EDO07385.1 - 0.0051 15.9 0.4 0.013 14.6 0.0 1.7 2 0 0 2 2 2 1 KaiC DUF2075 PF09848.4 EDO07385.1 - 0.0061 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EDO07385.1 - 0.09 11.6 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EDO07385.1 - 0.09 11.9 0.0 0.28 10.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.1 EDO07385.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-RING_2 PF13639.1 EDO07386.1 - 5.2e-14 51.7 4.8 1.2e-13 50.6 3.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDO07386.1 - 3.3e-10 39.9 1.1 6.6e-10 38.9 0.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDO07386.1 - 3.1e-09 36.3 4.4 7e-09 35.1 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO07386.1 - 1e-07 31.8 4.5 1e-07 31.8 3.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO07386.1 - 2e-07 30.5 2.6 3.6e-07 29.7 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO07386.1 - 1.9e-06 27.4 3.3 1.9e-06 27.4 2.3 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EDO07386.1 - 0.0079 16.0 4.3 0.053 13.3 3.0 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EDO07386.1 - 0.038 13.9 4.3 0.12 12.3 3.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EDO07386.1 - 0.068 13.2 5.5 0.17 11.9 3.8 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EDO07386.1 - 0.13 12.0 3.8 0.08 12.6 1.0 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 EDO07386.1 - 0.14 11.7 2.1 0.26 10.8 1.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EDO07386.1 - 2.3 8.1 6.6 1.6 8.6 2.6 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING PTPA PF03095.10 EDO07387.1 - 2e-77 260.3 0.2 2.6e-77 259.9 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein His_Phos_2 PF00328.17 EDO07388.1 - 6.3e-46 157.2 0.0 1.6e-44 152.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EDO07388.1 - 2.3e-06 27.2 0.0 5.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.17 EDO07388.1 - 0.00039 20.5 0.3 0.005 16.9 0.0 2.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Asp PF00026.18 EDO07389.1 - 1.8e-46 158.8 0.0 3.1e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDO07389.1 - 8.3e-05 22.5 0.0 0.00034 20.6 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EDO07389.1 - 0.00012 21.6 0.0 0.0082 15.7 0.0 2.6 2 1 1 3 3 3 1 Xylanase inhibitor C-terminal VPS28 PF03997.7 EDO07390.1 - 2.7e-29 102.1 0.3 1.2e-28 100.0 0.2 1.8 1 1 0 1 1 1 1 VPS28 protein GvpG PF05120.7 EDO07390.1 - 0.013 15.2 0.6 0.028 14.2 0.4 1.5 1 0 0 1 1 1 0 Gas vesicle protein G Birna_VP5 PF03042.9 EDO07391.1 - 0.24 10.9 5.9 0.41 10.1 4.1 1.3 1 0 0 1 1 1 0 Birnavirus VP5 protein ELFV_dehydrog PF00208.16 EDO07392.1 - 3.7e-78 262.4 0.1 4.5e-78 262.1 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EDO07392.1 - 4.8e-47 158.8 0.0 9.5e-47 157.8 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EDO07392.1 - 0.017 15.3 0.1 0.074 13.3 0.0 1.9 2 1 0 2 2 2 0 Putative NAD(P)-binding FAST_1 PF06743.10 EDO07393.1 - 0.00013 21.6 2.6 0.44 10.2 0.0 4.7 5 0 0 5 5 5 3 FAST kinase-like protein, subdomain 1 Adaptin_N PF01602.15 EDO07394.1 - 8.9e-56 189.2 2.4 8.9e-56 189.2 1.7 1.4 2 0 0 2 2 2 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EDO07394.1 - 4e-20 71.8 0.0 3.3e-09 36.5 0.0 2.8 2 0 0 2 2 2 2 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EDO07394.1 - 3.5e-14 52.6 0.8 6.9e-14 51.6 0.6 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EDO07394.1 - 4.1e-06 26.9 0.4 0.0027 17.9 0.0 3.7 4 0 0 4 4 4 1 HEAT repeats Cnd1 PF12717.2 EDO07394.1 - 0.0003 20.6 2.7 0.16 11.7 0.0 4.8 4 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EDO07394.1 - 0.0016 18.3 0.1 0.33 10.8 0.0 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF2435) HEAT PF02985.17 EDO07394.1 - 0.014 15.3 0.4 6.1 7.2 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Ribosomal_L18e PF00828.14 EDO07395.1 - 0.00027 21.3 0.6 0.00064 20.0 0.1 2.0 2 1 0 2 2 2 1 Ribosomal protein L18e/L15 Diphthamide_syn PF01866.12 EDO07396.1 - 3.5e-30 105.2 0.1 1.1e-29 103.6 0.1 1.7 1 1 0 1 1 1 1 Putative diphthamide synthesis protein COX2 PF00116.15 EDO07397.1 - 2.2e-36 124.3 0.0 2.6e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Ribosomal_L17 PF01196.14 EDO07398.1 - 6.3e-20 71.5 0.0 1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 MMR_HSR1 PF01926.18 EDO07399.1 - 1.8e-17 63.3 0.2 2.1e-14 53.4 0.0 3.1 2 1 1 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO07399.1 - 5.6e-07 28.9 0.5 3.2e-06 26.4 0.1 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EDO07399.1 - 0.014 14.6 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDO07399.1 - 0.065 13.0 1.4 13 5.5 0.0 3.5 3 1 1 4 4 4 0 Dynamin family Pkinase PF00069.20 EDO07401.1 - 1.7e-66 224.0 0.0 2.7e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO07401.1 - 6.7e-28 97.4 0.0 1e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO07401.1 - 0.00019 20.5 0.0 0.005 15.8 0.0 2.5 1 1 1 2 2 2 1 Kinase-like FeoB_N PF02421.13 EDO07401.1 - 0.042 13.1 0.1 0.075 12.3 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B ATP-grasp_2 PF08442.5 EDO07402.1 - 6.7e-56 188.8 0.1 1.1e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EDO07402.1 - 2.5e-20 72.6 0.3 4.1e-20 71.9 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EDO07402.1 - 0.00017 20.8 0.1 0.0018 17.5 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 EDO07402.1 - 0.00021 20.8 0.2 0.00039 20.0 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_4 PF13535.1 EDO07402.1 - 0.052 13.2 0.0 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain SF-assemblin PF06705.6 EDO07403.1 - 1.6e-09 37.2 15.7 2e-09 36.9 10.9 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Baculo_PEP_C PF04513.7 EDO07403.1 - 0.0002 21.2 5.5 0.0045 16.8 3.4 2.6 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus FlaF PF07309.6 EDO07403.1 - 0.023 14.5 5.0 8.5 6.2 0.0 2.7 2 1 1 3 3 3 0 Flagellar protein FlaF HSBP1 PF06825.7 EDO07403.1 - 0.028 13.9 0.5 0.087 12.4 0.0 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 MobA_MobL PF03389.10 EDO07403.1 - 0.046 13.1 0.5 0.079 12.3 0.3 1.3 1 0 0 1 1 1 0 MobA/MobL family Apolipoprotein PF01442.13 EDO07403.1 - 0.079 12.4 7.7 0.16 11.4 4.5 2.1 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain V_ATPase_I PF01496.14 EDO07403.1 - 0.11 10.3 4.2 0.15 9.8 2.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S46 PF10459.4 EDO07403.1 - 0.11 10.8 3.3 0.12 10.7 2.3 1.1 1 0 0 1 1 1 0 Peptidase S46 Corona_S2 PF01601.11 EDO07403.1 - 0.13 10.3 2.4 0.14 10.1 1.3 1.3 1 1 0 1 1 1 0 Coronavirus S2 glycoprotein CAP_N PF01213.14 EDO07403.1 - 0.13 11.5 1.0 0.61 9.3 0.1 2.0 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF4041 PF13250.1 EDO07403.1 - 0.14 11.7 3.0 2.5 7.7 0.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Fib_alpha PF08702.5 EDO07403.1 - 0.2 11.7 9.0 0.11 12.6 0.7 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BDV_P24 PF06595.6 EDO07403.1 - 0.24 11.1 5.2 0.56 9.9 0.1 2.2 1 1 1 2 2 2 0 Borna disease virus P24 protein DUF1664 PF07889.7 EDO07403.1 - 0.29 10.9 5.6 0.21 11.4 1.3 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Phasin PF05597.6 EDO07403.1 - 0.3 10.8 11.3 0.25 11.0 5.4 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF2746 PF10874.3 EDO07403.1 - 0.4 10.8 9.7 4.7 7.4 0.3 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2746) DUF1515 PF07439.6 EDO07403.1 - 0.5 10.2 5.0 1.5 8.6 1.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) SlyX PF04102.7 EDO07403.1 - 0.65 10.4 5.0 0.9 9.9 0.2 3.0 1 1 2 3 3 3 0 SlyX SPT16 PF08644.6 EDO07403.1 - 1 9.2 7.3 1.2 8.9 2.4 2.2 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Phe_tRNA-synt_N PF02912.13 EDO07403.1 - 1.8 8.3 11.4 2.9 7.6 2.4 3.5 2 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF2452 PF10504.4 EDO07403.1 - 1.9 7.7 5.1 9.4 5.4 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2452) Prefoldin_2 PF01920.15 EDO07403.1 - 2.7 7.8 11.6 6.4 6.5 1.4 3.8 2 1 2 4 4 4 0 Prefoldin subunit Kinetocho_Slk19 PF12709.2 EDO07403.1 - 5 7.2 10.3 2.2 8.3 1.7 3.3 3 1 0 3 3 3 0 Central kinetochore-associated PGBA_C PF15437.1 EDO07403.1 - 6.9 6.8 12.9 1.3 9.2 6.1 1.9 2 0 0 2 2 1 0 Plasminogen-binding protein pgbA C-terminal Ribosomal_L14e PF01929.12 EDO07404.1 - 7.7e-27 93.4 2.2 9.4e-27 93.1 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EDO07404.1 - 1e-05 25.0 0.0 2.9e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 KOW motif DUF773 PF05600.7 EDO07405.1 - 1.6e-16 60.1 18.3 1e-11 44.3 3.6 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF773) TPR_MLP1_2 PF07926.7 EDO07405.1 - 0.0016 18.2 1.3 0.0016 18.2 0.9 3.1 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein MitMem_reg PF13012.1 EDO07405.1 - 0.013 15.5 0.7 0.05 13.6 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function CCDC155 PF14662.1 EDO07405.1 - 0.021 14.4 0.8 0.021 14.4 0.6 3.2 4 1 2 6 6 6 0 Coiled-coil region of CCDC155 DUF1515 PF07439.6 EDO07405.1 - 0.036 13.8 1.2 7.5 6.4 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1515) KH_5 PF13184.1 EDO07405.1 - 0.077 12.8 1.8 6.2 6.7 0.1 3.5 4 0 0 4 4 4 0 NusA-like KH domain MutS_III PF05192.13 EDO07405.1 - 0.09 12.5 1.8 4.7 6.9 1.5 2.8 1 1 0 1 1 1 0 MutS domain III DUF641 PF04859.7 EDO07405.1 - 0.14 11.9 5.0 2.1 8.1 0.1 2.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Prefoldin PF02996.12 EDO07405.1 - 0.41 10.2 14.6 0.18 11.4 2.2 4.0 4 1 0 4 4 4 0 Prefoldin subunit COG2 PF06148.6 EDO07405.1 - 0.84 9.5 6.2 0.45 10.3 0.7 3.1 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 EDO07405.1 - 1.8 8.0 9.6 5.2 6.6 4.5 2.7 2 1 0 2 2 2 0 IncA protein DUF948 PF06103.6 EDO07405.1 - 2.3 8.1 9.0 2.6 7.9 0.4 4.3 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF745 PF05335.8 EDO07405.1 - 2.8 7.4 6.3 5.8 6.3 2.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF745) SNARE PF05739.14 EDO07406.1 - 3.6e-05 23.3 0.7 0.00012 21.7 0.3 2.1 2 0 0 2 2 2 1 SNARE domain DUF2383 PF09537.5 EDO07406.1 - 0.0021 18.2 7.0 0.1 12.8 0.1 3.7 2 1 1 4 4 3 1 Domain of unknown function (DUF2383) Spc42p PF11544.3 EDO07406.1 - 0.0083 16.0 8.6 0.014 15.2 0.1 3.4 2 1 0 3 3 3 1 Spindle pole body component Spc42p Retrotrans_gag PF03732.12 EDO07406.1 - 0.086 12.9 9.4 0.12 12.4 0.5 3.1 1 1 2 3 3 3 0 Retrotransposon gag protein DUF737 PF05300.6 EDO07406.1 - 0.14 12.1 7.3 0.17 11.8 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) LMBR1 PF04791.11 EDO07406.1 - 0.14 10.6 2.6 0.2 10.2 1.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Syntaxin PF00804.20 EDO07406.1 - 0.17 12.0 10.4 0.73 10.0 2.7 2.5 2 1 0 2 2 2 0 Syntaxin SlyX PF04102.7 EDO07406.1 - 0.31 11.4 4.7 0.44 10.9 0.3 2.8 3 0 0 3 3 2 0 SlyX Fib_alpha PF08702.5 EDO07406.1 - 0.53 10.3 14.0 2.5 8.2 4.4 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 EDO07406.1 - 0.76 9.5 7.5 0.54 10.0 0.1 2.5 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bap31 PF05529.7 EDO07406.1 - 1.5 8.2 8.5 6 6.2 5.8 2.2 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Syntaxin-6_N PF09177.6 EDO07406.1 - 2.4 8.6 11.9 17 5.9 0.2 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal IncA PF04156.9 EDO07406.1 - 2.6 7.5 12.1 7 6.2 4.9 2.6 1 1 1 2 2 2 0 IncA protein Vac_Fusion PF02346.11 EDO07406.1 - 4.1 6.8 6.9 18 4.8 0.0 3.5 3 0 0 3 3 3 0 Chordopoxvirus fusion protein TACC PF05010.9 EDO07406.1 - 4.9 6.8 13.7 15 5.2 9.3 1.8 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Nop10p PF04135.7 EDO07407.1 - 3.3e-22 77.9 0.1 3.7e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Rtf2 PF04641.7 EDO07408.1 - 2e-45 155.0 0.2 2.6e-45 154.6 0.2 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EDO07408.1 - 8.9e-05 22.1 3.7 0.00024 20.7 2.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EDO07408.1 - 0.0014 18.1 6.4 0.42 10.1 0.0 3.4 3 1 0 3 3 3 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EDO07408.1 - 0.017 14.9 5.0 0.032 14.0 3.5 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_3 PF14369.1 EDO07408.1 - 0.05 13.5 0.1 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 zinc-finger zf-C3HC4_3 PF13920.1 EDO07408.1 - 0.3 10.7 3.8 0.54 9.9 2.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_6 PF12697.2 EDO07409.1 - 7.6e-14 52.1 0.0 1.4e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO07409.1 - 3.1e-11 43.2 0.0 1.1e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDO07409.1 - 3.4e-08 33.2 1.1 1.3e-06 28.2 0.2 2.4 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EDO07409.1 - 7.5e-05 22.4 0.0 0.00026 20.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EDO07409.1 - 0.00036 20.1 0.1 0.0057 16.2 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDO07409.1 - 0.00071 18.8 0.0 0.087 12.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EDO07409.1 - 0.0073 15.7 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase LIP PF03583.9 EDO07409.1 - 0.052 12.7 0.1 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Secretory lipase zf-HC5HC2H_2 PF13832.1 EDO07410.1 - 1.2e-18 67.1 27.7 2.1e-12 46.9 4.6 3.8 3 1 0 3 3 3 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EDO07410.1 - 1.3e-11 44.5 13.9 2.1e-08 34.1 1.3 4.4 3 1 1 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.24 EDO07410.1 - 3.4e-05 23.4 36.8 9.3e-05 22.0 4.8 4.5 4 1 0 4 4 4 3 PHD-finger C1_1 PF00130.17 EDO07410.1 - 0.0024 17.5 2.8 0.0024 17.5 2.0 4.4 4 0 0 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EDO07410.1 - 0.0075 15.5 16.3 2.8 7.3 0.1 3.9 2 1 0 2 2 2 2 PHD-finger Sybindin PF04099.7 EDO07411.1 - 1.2e-16 60.6 0.0 1.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EDO07411.1 - 0.024 14.4 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region MutS_V PF00488.16 EDO07412.1 - 2.4e-17 63.1 0.1 5.9e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 MutS domain V AAA_23 PF13476.1 EDO07412.1 - 1.5e-05 25.4 0.0 3.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain GIY-YIG PF01541.19 EDO07412.1 - 0.00013 22.2 0.1 0.00083 19.6 0.1 2.3 1 1 0 1 1 1 1 GIY-YIG catalytic domain Arch_ATPase PF01637.13 EDO07412.1 - 0.00024 20.9 0.0 0.00079 19.1 0.0 1.8 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EDO07412.1 - 0.00045 20.1 0.0 0.0034 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EDO07412.1 - 0.00086 18.7 0.1 0.002 17.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EDO07412.1 - 0.0063 16.5 0.3 0.031 14.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EDO07412.1 - 0.0085 16.5 0.1 0.37 11.2 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein Sigma54_activ_2 PF14532.1 EDO07412.1 - 0.0085 16.1 0.0 0.029 14.4 0.0 1.9 2 0 0 2 2 1 1 Sigma-54 interaction domain MMR_HSR1 PF01926.18 EDO07412.1 - 0.024 14.5 0.4 0.14 12.0 0.2 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.1 EDO07412.1 - 0.052 13.1 0.0 0.19 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EDO07412.1 - 0.053 13.8 0.4 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 EDO07412.1 - 0.086 12.3 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family SMC_N PF02463.14 EDO07412.1 - 0.18 11.0 3.3 0.47 9.6 0.1 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain MutS_I PF01624.15 EDO07413.1 - 0.014 15.4 0.5 0.14 12.1 0.0 2.8 2 1 1 3 3 3 0 MutS domain I Ribonuc_red_sm PF00268.16 EDO07414.1 - 3.9e-108 360.7 0.3 4.8e-108 360.4 0.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain GTP_EFTU PF00009.22 EDO07415.1 - 9.4e-56 188.2 0.1 1.4e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDO07415.1 - 5.7e-35 119.4 0.7 9.8e-34 115.4 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDO07415.1 - 1.4e-14 53.9 0.1 4.2e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO07415.1 - 3.5e-05 23.7 0.2 0.00017 21.4 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EDO07415.1 - 0.00044 19.8 0.1 0.0018 17.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.13 EDO07415.1 - 0.066 13.0 0.7 0.11 12.3 0.1 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.22 EDO07416.1 - 9.4e-56 188.2 0.1 1.4e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDO07416.1 - 5.7e-35 119.4 0.7 9.8e-34 115.4 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDO07416.1 - 1.4e-14 53.9 0.1 4.2e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO07416.1 - 3.5e-05 23.7 0.2 0.00017 21.4 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EDO07416.1 - 0.00044 19.8 0.1 0.0018 17.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.13 EDO07416.1 - 0.066 13.0 0.7 0.11 12.3 0.1 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain tRNA-synt_1c PF00749.16 EDO07417.1 - 1.9e-69 233.7 0.0 2e-67 227.0 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain MerE PF05052.7 EDO07417.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 MerE protein tRNA-synt_1f PF01921.13 EDO07417.1 - 0.14 10.7 0.1 0.32 9.6 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (K) Pkinase PF00069.20 EDO07418.1 - 4e-75 252.3 0.0 4.5e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO07418.1 - 5.6e-34 117.3 0.0 7e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO07418.1 - 0.00011 21.3 0.0 0.00025 20.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EDO07418.1 - 0.0016 17.8 0.0 0.0032 16.8 0.0 1.4 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 EDO07418.1 - 0.031 14.0 0.0 0.066 12.9 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EDO07418.1 - 0.17 10.9 0.1 0.37 9.8 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cmc1 PF08583.5 EDO07419.1 - 0.085 12.6 0.8 0.13 12.0 0.6 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DnaJ PF00226.26 EDO07420.1 - 5.1e-21 74.1 5.6 8.2e-21 73.5 3.9 1.3 1 0 0 1 1 1 1 DnaJ domain DUF2051 PF09738.4 EDO07420.1 - 0.023 14.0 0.7 0.03 13.6 0.5 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) RCC1 PF00415.13 EDO07421.1 - 1e-27 96.0 10.7 2.3e-08 34.1 0.1 7.9 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDO07421.1 - 4.1e-16 58.0 9.8 7.4e-05 22.2 0.0 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.20 EDO07422.1 - 2.7e-18 66.0 0.0 2.7e-10 39.8 0.1 3.3 3 1 0 3 3 3 2 Protein kinase domain UQ_con PF00179.21 EDO07423.1 - 5.3e-48 162.0 0.1 6.7e-48 161.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO07423.1 - 6.9e-06 25.8 0.0 9.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_4 PF14555.1 EDO07423.1 - 0.00061 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 EDO07423.1 - 0.00092 18.9 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RWD PF05773.17 EDO07423.1 - 0.0073 16.1 0.4 0.015 15.1 0.3 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EDO07423.1 - 0.033 13.8 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 UEV domain Tim17 PF02466.14 EDO07424.1 - 1.8e-17 63.5 6.1 2.2e-17 63.3 4.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UEV PF05743.8 EDO07425.1 - 1.2e-15 57.2 0.0 2.2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain DUF3142 PF11340.3 EDO07425.1 - 0.00033 20.3 0.3 0.0013 18.4 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3142) UQ_con PF00179.21 EDO07425.1 - 0.00099 18.5 0.1 0.0018 17.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Vps23_core PF09454.5 EDO07425.1 - 0.0016 18.0 0.4 0.0035 16.9 0.3 1.5 1 0 0 1 1 1 1 Vps23 core domain Glutaredoxin PF00462.19 EDO07426.1 - 3.2e-05 23.8 0.0 6.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin COX16 PF14138.1 EDO07426.1 - 0.097 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Sas10 PF09368.5 EDO07429.1 - 7e-22 77.3 6.7 7e-22 77.3 4.6 2.8 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EDO07429.1 - 7.4e-15 54.9 0.8 7.4e-15 54.9 0.5 2.4 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Snapin_Pallidin PF14712.1 EDO07429.1 - 0.33 11.2 10.7 4.6 7.6 0.1 4.5 4 0 0 4 4 4 0 Snapin/Pallidin Filamin PF00630.14 EDO07430.1 - 1e-14 54.8 0.1 4.8e-12 46.3 0.0 4.0 4 0 0 4 4 4 1 Filamin/ABP280 repeat Streptin-Immun PF11083.3 EDO07430.1 - 0.04 13.8 2.0 0.058 13.3 0.1 2.2 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein DUF4061 PF13270.1 EDO07432.1 - 0.14 12.3 0.1 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Ank_2 PF12796.2 EDO07434.1 - 2.1e-20 72.8 0.0 3.3e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EDO07434.1 - 1.3e-19 68.8 1.6 4.6e-11 41.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EDO07434.1 - 4.4e-16 58.9 0.2 1.7e-11 44.3 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ACBP PF00887.14 EDO07434.1 - 6.5e-16 57.7 0.0 1.1e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.1 EDO07434.1 - 4e-15 55.4 2.0 5.6e-09 35.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO07434.1 - 1.2e-13 49.8 0.1 2.5e-06 27.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Elf1 PF05129.8 EDO07435.1 - 0.033 13.8 0.1 0.08 12.6 0.1 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2_4 PF13894.1 EDO07435.1 - 6.2 7.3 5.7 11 6.6 0.1 3.4 4 0 0 4 4 4 0 C2H2-type zinc finger SET PF00856.23 EDO07436.1 - 7.2e-09 36.1 0.0 1.7e-06 28.4 0.0 2.2 1 1 1 2 2 2 2 SET domain Sialidase_penC PF12135.3 EDO07436.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 Sialidase enzyme penultimate C terminal domain Nop PF01798.13 EDO07437.1 - 8.1e-50 168.0 0.5 1.8e-49 166.8 0.3 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EDO07437.1 - 1.4e-23 82.3 0.0 3e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EDO07437.1 - 8.9e-20 70.6 0.0 8.9e-20 70.6 0.0 3.1 3 0 0 3 3 3 1 NOP5NT (NUC127) domain MOZ_SAS PF01853.13 EDO07439.1 - 2e-72 242.4 0.1 2.9e-72 241.8 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EDO07439.1 - 1.6e-11 43.7 0.7 3.4e-11 42.6 0.5 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Peptidase_M16_C PF05193.16 EDO07440.1 - 5.3e-19 68.6 0.1 9.6e-11 41.6 0.0 4.3 4 0 0 4 4 4 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EDO07440.1 - 3.2e-07 30.1 0.0 1.2e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Fib_alpha PF08702.5 EDO07440.1 - 0.78 9.8 1.9 1.9 8.6 1.3 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HSP90 PF00183.13 EDO07441.1 - 1.1e-73 248.5 11.6 7.2e-73 245.7 6.6 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 EDO07441.1 - 5.2e-14 52.0 0.1 1.1e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDO07441.1 - 1.2e-06 28.1 0.0 3.1e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hen1_L PF12623.2 EDO07441.1 - 0.0039 15.9 0.0 0.007 15.1 0.0 1.3 1 0 0 1 1 1 1 RNA repair, ligase-Pnkp-associating, region of Hen1 Clat_adaptor_s PF01217.15 EDO07442.1 - 6.8e-48 161.9 4.4 7.7e-48 161.8 3.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MarR PF01047.17 EDO07443.1 - 0.087 12.5 0.0 0.34 10.6 0.0 2.0 1 0 0 1 1 1 0 MarR family DNA_mis_repair PF01119.14 EDO07444.1 - 1.3e-25 89.1 0.6 2.9e-25 88.0 0.4 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EDO07444.1 - 6.1e-16 58.3 0.0 1.3e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDO07444.1 - 1.4e-12 47.2 0.0 3.2e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ras PF00071.17 EDO07445.1 - 1.5e-47 161.0 0.0 1.8e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO07445.1 - 6.1e-15 55.7 0.0 2.1e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EDO07445.1 - 1.2e-11 44.1 0.0 1.6e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EDO07445.1 - 0.0014 18.7 0.0 0.0057 16.8 0.0 1.9 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EDO07445.1 - 0.0023 17.0 0.0 0.003 16.7 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EDO07445.1 - 0.026 13.2 0.2 0.35 9.4 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit AAA_16 PF13191.1 EDO07445.1 - 0.03 14.3 0.2 0.066 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EDO07445.1 - 0.037 14.1 0.2 0.2 11.7 0.1 2.1 1 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EDO07445.1 - 0.045 13.7 0.0 0.079 12.9 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EDO07445.1 - 0.088 13.1 0.1 0.91 9.8 0.0 2.3 2 1 1 3 3 3 0 ABC transporter AAA_29 PF13555.1 EDO07445.1 - 0.12 11.9 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 EDO07445.1 - 0.12 11.2 0.1 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Septin PF00735.13 EDO07445.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Septin DUF258 PF03193.11 EDO07445.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EDO07445.1 - 0.14 11.6 0.1 0.22 11.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EDO07445.1 - 0.18 11.4 0.5 0.29 10.7 0.1 1.6 2 0 0 2 2 2 0 NACHT domain efThoc1 PF11957.3 EDO07446.1 - 0.00022 19.8 1.6 0.0026 16.3 0.1 2.8 2 1 0 2 2 2 1 THO complex subunit 1 transcription elongation factor tRNA-synt_1b PF00579.20 EDO07448.1 - 2.8e-40 138.3 0.1 1.3e-39 136.0 0.1 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 EDO07448.1 - 9.7e-06 24.9 0.0 5e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 S4 domain DUF3273 PF11677.3 EDO07449.1 - 9.2e-117 388.9 15.2 1.1e-116 388.7 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF2484 PF10658.4 EDO07449.1 - 0.58 10.3 5.5 0.18 11.9 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) Clat_adaptor_s PF01217.15 EDO07451.1 - 3.3e-42 143.5 2.0 3.7e-42 143.3 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DEAD PF00270.24 EDO07452.1 - 2.5e-42 144.2 0.1 3.2e-41 140.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO07452.1 - 1.1e-29 102.0 0.4 2e-28 98.0 0.2 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EDO07452.1 - 3.4e-05 23.5 0.1 0.0002 21.0 0.0 2.1 1 1 1 2 2 2 1 Part of AAA domain ResIII PF04851.10 EDO07452.1 - 0.00046 20.0 0.1 0.004 16.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EDO07452.1 - 0.0031 17.1 0.0 0.0071 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 EDO07452.1 - 0.044 12.9 0.0 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein CMS1 PF14617.1 EDO07452.1 - 0.074 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_11 PF13086.1 EDO07452.1 - 0.092 12.3 0.4 0.18 11.3 0.3 1.8 1 1 0 1 1 1 0 AAA domain RFX_DNA_binding PF02257.10 EDO07453.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain F-box-like PF12937.2 EDO07456.1 - 0.068 12.9 0.2 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 F-box-like CAF1C_H4-bd PF12265.3 EDO07457.1 - 7.5e-21 73.8 0.1 2.6e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 EDO07457.1 - 3e-20 71.2 2.7 1.7e-05 24.5 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Myosin_head PF00063.16 EDO07458.1 - 7.6e-194 645.6 0.2 9.8e-194 645.2 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) WD40 PF00400.27 EDO07458.1 - 7.8e-13 47.7 5.1 0.00034 20.3 0.1 7.1 7 1 0 7 7 7 3 WD domain, G-beta repeat IQ PF00612.22 EDO07458.1 - 1.9e-11 42.5 29.1 0.00081 18.8 0.3 5.7 5 0 0 5 5 5 3 IQ calmodulin-binding motif Zeta_toxin PF06414.7 EDO07458.1 - 4e-05 22.8 0.1 0.057 12.5 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.1 EDO07458.1 - 0.00015 21.8 1.1 0.28 11.1 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EDO07458.1 - 0.00062 19.9 2.1 1.1 9.3 0.0 4.0 3 1 0 3 3 3 1 AAA domain Nup160 PF11715.3 EDO07458.1 - 0.0025 16.0 0.1 0.01 14.0 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 AAA_33 PF13671.1 EDO07458.1 - 0.0046 16.8 0.6 0.76 9.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain V_ATPase_I PF01496.14 EDO07458.1 - 0.044 11.6 2.7 0.069 10.9 1.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 EDO07458.1 - 0.078 12.8 14.4 0.048 13.4 7.7 2.0 2 0 0 2 2 2 0 Tropomyosin like AAA_17 PF13207.1 EDO07458.1 - 0.13 13.1 0.0 9 7.1 0.0 3.2 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.4 EDO07458.1 - 0.23 9.6 13.7 0.012 13.9 5.3 1.7 2 0 0 2 2 2 0 Transmembrane protein CENP-Q PF13094.1 EDO07458.1 - 0.32 11.0 9.3 0.75 9.8 4.3 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Mnd1 PF03962.10 EDO07458.1 - 0.33 10.6 12.8 0.16 11.5 5.6 2.3 1 1 1 2 2 2 0 Mnd1 family DivIC PF04977.10 EDO07458.1 - 0.44 10.0 9.7 0.2 11.1 3.4 2.6 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 EDO07458.1 - 1.2 8.6 12.9 0.088 12.3 5.3 1.7 2 0 0 2 2 2 0 IncA protein Viral_P18 PF04521.8 EDO07458.1 - 5.6 6.4 7.6 2.4 7.6 2.8 2.2 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein CENP-F_leu_zip PF10473.4 EDO07458.1 - 7.7 6.3 15.7 0.98 9.2 7.8 1.7 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PI-PLC-X PF00388.14 EDO07459.1 - 1.6e-40 137.8 0.0 3.2e-40 136.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EDO07459.1 - 2.4e-24 85.5 0.0 7.5e-24 83.9 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EDO07459.1 - 7e-09 35.4 0.0 2.5e-08 33.6 0.0 2.0 1 1 0 1 1 1 1 C2 domain Mcp5_PH PF12814.2 EDO07459.1 - 2.5e-05 24.2 0.0 5.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology RAP-1 PF03085.10 EDO07463.1 - 0.11 11.7 0.2 0.15 11.3 0.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YARHG PF13308.1 EDO07463.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.7 1 1 0 1 1 1 0 YARHG domain Utp14 PF04615.8 EDO07464.1 - 5.1e-18 64.6 64.7 7.5e-18 64.0 21.1 3.8 1 1 3 4 4 4 2 Utp14 protein DUF2183 PF09949.4 EDO07464.1 - 0.33 10.9 2.6 0.38 10.7 0.1 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2183) Myb_DNA-binding PF00249.26 EDO07465.1 - 2.8e-05 24.0 0.0 6.7e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.12 EDO07465.1 - 0.028 14.5 0.0 0.075 13.1 0.0 1.7 1 0 0 1 1 1 0 SWIRM domain DTHCT PF08070.6 EDO07466.1 - 0.04 14.5 0.8 0.057 14.0 0.6 1.2 1 0 0 1 1 1 0 DTHCT (NUC029) region RNA_pol_Rpc34 PF05158.7 EDO07467.1 - 5.8e-39 134.1 2.4 5.7e-30 104.6 0.1 2.3 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 EDO07467.1 - 0.0006 19.6 0.1 0.0017 18.1 0.0 1.8 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_20 PF12840.2 EDO07467.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4423 PF14394.1 EDO07467.1 - 0.062 12.8 0.2 1.6 8.2 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4423) HA2 PF04408.18 EDO07468.1 - 5.2e-25 87.4 0.1 1.9e-24 85.6 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDO07468.1 - 7.8e-23 80.4 0.0 1.7e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EDO07468.1 - 1.9e-11 43.6 0.0 6.5e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO07468.1 - 7.4e-08 32.0 0.2 3.4e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDO07468.1 - 3.1e-06 27.3 0.0 0.00016 21.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EDO07468.1 - 0.0019 17.1 0.0 0.0042 16.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EDO07468.1 - 0.021 14.5 0.2 0.051 13.3 0.2 1.7 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EDO07468.1 - 0.032 13.6 0.0 0.1 12.0 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EDO07468.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.9 3 1 0 3 3 3 0 AAA domain DIM1 PF02966.11 EDO07469.1 - 1.7e-65 218.5 0.2 1.9e-65 218.3 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EDO07469.1 - 0.015 15.0 0.1 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin HALZ PF02183.13 EDO07470.1 - 0.0028 17.3 4.8 0.0055 16.3 3.3 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper EMP24_GP25L PF01105.19 EDO07470.1 - 0.011 15.5 2.4 0.011 15.5 1.7 1.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD GrpE PF01025.14 EDO07470.1 - 0.057 12.9 1.8 0.11 11.9 1.3 1.5 1 0 0 1 1 1 0 GrpE DivIC PF04977.10 EDO07470.1 - 0.18 11.2 4.5 0.22 11.0 1.3 2.3 2 0 0 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.14 EDO07470.1 - 0.4 8.4 4.9 0.18 9.5 1.5 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Cep57_MT_bd PF06657.8 EDO07470.1 - 0.6 10.0 3.6 0.26 11.2 0.4 1.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Uso1_p115_C PF04871.8 EDO07470.1 - 0.72 9.7 7.1 0.16 11.8 1.0 2.4 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3391 PF11871.3 EDO07470.1 - 0.92 9.7 3.8 0.39 10.9 0.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF904 PF06005.7 EDO07470.1 - 0.98 9.7 10.6 0.054 13.7 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) PEPCK_ATP PF01293.15 EDO07472.1 - 0.098 11.1 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase CDC50 PF03381.10 EDO07474.1 - 2.9e-21 75.8 0.5 4.5e-21 75.2 0.2 1.5 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4311 PF14188.1 EDO07474.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) AMA-1 PF02430.10 EDO07475.1 - 3e-205 682.5 2.8 3.5e-205 682.3 1.9 1.0 1 0 0 1 1 1 1 Apical membrane antigen 1 Molydop_binding PF01568.16 EDO07476.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain NARP1 PF12569.3 EDO07477.1 - 6.9e-28 97.6 13.0 6.1e-16 58.2 0.2 3.8 4 0 0 4 4 4 3 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 EDO07477.1 - 6.2e-13 49.0 0.8 0.003 18.1 0.0 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EDO07477.1 - 6.9e-11 41.6 8.7 0.00066 19.2 0.1 5.3 5 1 0 5 5 5 2 TPR repeat TPR_2 PF07719.12 EDO07477.1 - 2.7e-09 36.2 15.9 0.4 10.7 0.1 7.5 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDO07477.1 - 7.4e-09 35.4 0.4 0.0011 18.9 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDO07477.1 - 9.4e-09 35.1 0.0 0.45 11.2 0.0 6.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDO07477.1 - 1.4e-08 33.9 11.6 4.6e-05 22.8 0.1 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO07477.1 - 1.6e-05 24.3 8.3 0.0023 17.5 0.1 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDO07477.1 - 0.00039 20.3 1.1 0.45 10.8 0.0 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EDO07477.1 - 0.00046 20.2 8.8 0.0095 16.0 0.1 4.5 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDO07477.1 - 0.0012 19.2 4.7 5 7.8 0.3 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDO07477.1 - 0.0016 18.7 4.1 4.3 7.7 0.1 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDO07477.1 - 0.0083 15.9 0.4 0.29 11.0 0.1 3.2 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Xol-1_N PF09108.5 EDO07477.1 - 0.0095 15.6 0.1 0.03 14.0 0.1 1.8 1 0 0 1 1 1 1 Switch protein XOL-1, N-terminal TPR_21 PF09976.4 EDO07477.1 - 0.027 14.4 0.4 2.1 8.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DNApol3-delta_C PF09115.5 EDO07477.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal Prp18 PF02840.10 EDO07478.1 - 3e-55 186.0 2.5 3e-55 186.0 1.7 2.6 2 1 1 3 3 3 1 Prp18 domain PRP4 PF08799.6 EDO07478.1 - 9.4e-11 40.7 0.3 1.7e-10 39.9 0.2 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Fe_hyd_SSU PF02256.12 EDO07478.1 - 0.011 15.7 7.1 0.048 13.6 0.1 3.2 3 0 0 3 3 3 0 Iron hydrogenase small subunit DUF1707 PF08044.6 EDO07478.1 - 0.098 12.4 0.3 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) CG-1 PF03859.11 EDO07478.1 - 0.55 9.7 5.1 1.3 8.5 2.0 2.4 2 0 0 2 2 2 0 CG-1 domain Ldh_1_N PF00056.18 EDO07479.1 - 6.8e-33 113.4 0.3 1.2e-32 112.6 0.2 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EDO07479.1 - 2.3e-31 108.8 0.0 4.4e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 EDO07479.1 - 6.3e-05 22.3 0.2 0.0002 20.7 0.0 1.9 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase TMEM240 PF15207.1 EDO07479.1 - 0.059 12.9 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 TMEM240 family UDPG_MGDP_dh_N PF03721.9 EDO07479.1 - 0.084 12.2 0.3 0.21 10.9 0.2 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1512 PF07431.7 EDO07479.1 - 0.097 11.3 0.3 0.15 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) DUF1168 PF06658.7 EDO07480.1 - 2.2e-32 111.5 11.9 2.8e-32 111.1 8.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DRY_EERY PF09750.4 EDO07480.1 - 0.043 13.9 5.3 0.077 13.1 3.7 1.4 1 0 0 1 1 1 0 Alternative splicing regulator Peptidase_S49_N PF08496.5 EDO07480.1 - 1.4 8.6 6.6 2 8.1 4.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Peptidase_S30 PF01577.11 EDO07480.1 - 1.6 8.0 13.5 2.2 7.6 9.3 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease NAD_binding_1 PF00175.16 EDO07481.1 - 3e-16 59.9 0.0 3.8e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EDO07481.1 - 0.00081 19.3 0.2 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Cnl2_NKP2 PF09447.5 EDO07482.1 - 0.05 13.2 0.1 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Cnl2/NKP2 family protein EGF PF00008.22 EDO07483.1 - 0.00052 19.9 41.8 0.0022 17.9 4.2 4.7 3 1 0 3 3 3 2 EGF-like domain EGF_2 PF07974.8 EDO07483.1 - 0.0063 16.6 5.6 0.0063 16.6 3.9 4.1 4 1 0 4 4 4 2 EGF-like domain EGF_alliinase PF04863.8 EDO07483.1 - 0.016 15.1 1.6 0.016 15.1 1.1 3.3 2 1 2 4 4 4 0 Alliinase EGF-like domain EGF_3 PF12947.2 EDO07483.1 - 0.03 14.2 7.5 0.03 14.2 5.2 3.9 3 1 0 3 3 3 0 EGF domain Acetyltransf_1 PF00583.19 EDO07484.1 - 4.1e-11 42.7 0.0 6.4e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO07484.1 - 3e-09 36.9 0.0 5.1e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDO07484.1 - 1.2e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDO07484.1 - 4.5e-05 23.3 0.0 8.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO07484.1 - 0.0012 18.9 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDO07484.1 - 0.0013 18.9 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EDO07484.1 - 0.018 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EDO07484.1 - 0.098 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 HECT PF00632.20 EDO07485.1 - 1.1e-44 152.8 0.0 2.3e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_4 PF13637.1 EDO07485.1 - 4.3e-09 36.6 5.9 4.4e-05 23.8 0.1 5.3 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDO07485.1 - 7.4e-09 35.8 0.1 5.1e-08 33.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDO07485.1 - 2.9e-07 30.4 0.4 0.0062 16.7 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EDO07485.1 - 1e-06 28.2 0.5 0.00021 20.9 0.0 3.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 EDO07485.1 - 0.00066 19.6 2.5 0.1 12.8 0.0 5.0 4 0 0 4 4 4 1 Ankyrin repeat UPF0086 PF01868.11 EDO07486.1 - 1.4e-06 27.8 0.0 3e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function UPF0086 DUF1846 PF08903.6 EDO07487.1 - 0.061 11.7 2.2 0.11 10.9 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1846) Myb_DNA-binding PF00249.26 EDO07487.1 - 0.2 11.7 1.8 0.46 10.5 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain Herpes_env PF01673.13 EDO07487.1 - 0.41 9.1 2.6 0.79 8.1 1.8 1.4 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein CDP-OH_P_transf PF01066.16 EDO07488.1 - 5.8e-20 71.4 1.1 5.8e-20 71.4 0.8 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.20 EDO07489.1 - 6.2e-28 97.6 0.0 1.3e-17 63.7 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO07489.1 - 1.6e-13 50.3 0.0 9.2e-09 34.7 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EDO07489.1 - 0.044 12.5 0.1 0.078 11.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ERp29_N PF07912.8 EDO07489.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 ERp29, N-terminal domain KH_1 PF00013.24 EDO07490.1 - 5.2e-08 32.4 0.0 1.2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EDO07490.1 - 7.8e-06 25.4 6.4 0.021 14.4 0.6 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 EDO07490.1 - 1.1e-05 25.0 0.8 0.082 12.6 0.1 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 EDO07490.1 - 3.5e-05 23.5 4.2 0.0039 17.0 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EDO07490.1 - 0.00015 21.3 0.1 0.00035 20.1 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 EDO07490.1 - 0.036 13.7 6.6 0.55 9.9 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle MFS_1 PF07690.11 EDO07492.1 - 2.5e-25 88.9 32.9 2.5e-25 88.9 22.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily SUV3_C PF12513.3 EDO07493.1 - 2e-14 52.7 0.1 4.7e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EDO07493.1 - 9e-13 47.9 0.2 3.8e-12 45.8 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PAS_10 PF13596.1 EDO07495.1 - 0.024 14.8 0.4 0.3 11.3 0.1 3.0 3 0 0 3 3 3 0 PAS domain Helicase_C PF00271.26 EDO07496.1 - 9.2e-10 38.2 0.0 3.2e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EDO07496.1 - 0.0064 14.9 0.0 0.011 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) GUCT PF08152.7 EDO07496.1 - 0.13 12.2 0.0 0.63 10.0 0.0 2.1 2 0 0 2 2 2 0 GUCT (NUC152) domain Serpin PF00079.15 EDO07496.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) RAP PF08373.5 EDO07497.1 - 0.00095 18.9 0.2 0.0035 17.1 0.2 1.9 2 0 0 2 2 2 1 RAP domain AAA PF00004.24 EDO07498.1 - 3e-85 283.0 0.0 6.6e-47 159.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO07498.1 - 5.8e-11 42.6 0.1 0.0018 18.3 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EDO07498.1 - 6e-11 42.5 0.0 2e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDO07498.1 - 6.8e-11 42.4 0.5 0.001 19.1 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 EDO07498.1 - 7.8e-11 41.8 0.0 0.00036 20.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EDO07498.1 - 1.5e-10 41.9 0.0 0.00011 23.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EDO07498.1 - 2.3e-10 39.9 0.0 0.00022 20.3 0.0 2.8 2 2 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EDO07498.1 - 9.9e-10 38.4 0.0 0.00017 21.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EDO07498.1 - 2.9e-09 36.8 0.0 0.00052 19.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EDO07498.1 - 1.5e-08 34.2 0.0 0.0037 16.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EDO07498.1 - 1.1e-07 31.1 0.0 0.017 14.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EDO07498.1 - 1.4e-07 31.1 3.9 1.1 8.6 0.1 4.6 3 2 1 5 5 4 2 AAA domain Sigma54_activat PF00158.21 EDO07498.1 - 7e-07 28.8 0.0 0.38 10.2 0.0 3.8 3 1 0 3 3 3 2 Sigma-54 interaction domain AAA_19 PF13245.1 EDO07498.1 - 9.2e-07 28.5 0.1 0.075 12.7 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 EDO07498.1 - 1.3e-06 28.5 0.0 0.045 13.9 0.0 3.2 4 0 0 4 4 2 2 RNA helicase ABC_tran PF00005.22 EDO07498.1 - 1.5e-06 28.5 0.0 0.084 13.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_18 PF13238.1 EDO07498.1 - 2.6e-06 27.7 0.0 0.086 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EDO07498.1 - 3e-06 26.5 1.4 0.031 13.4 0.1 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EDO07498.1 - 1e-05 24.4 0.1 0.08 11.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_28 PF13521.1 EDO07498.1 - 1.4e-05 25.1 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EDO07498.1 - 4e-05 23.3 0.1 0.36 10.4 0.0 3.1 3 0 0 3 3 3 2 NACHT domain CPT PF07931.7 EDO07498.1 - 7.6e-05 22.4 0.0 0.0034 17.0 0.0 2.4 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.13 EDO07498.1 - 0.00029 20.4 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EDO07498.1 - 0.00038 20.2 0.0 0.28 10.8 0.0 2.9 2 1 1 3 3 3 1 Archaeal ATPase AAA_3 PF07726.6 EDO07498.1 - 0.00041 19.9 0.0 0.92 9.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EDO07498.1 - 0.0011 17.9 0.0 0.21 10.4 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Parvo_NS1 PF01057.12 EDO07498.1 - 0.0014 17.5 0.2 0.49 9.2 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EDO07498.1 - 0.0019 17.1 0.0 1.1 8.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_24 PF13479.1 EDO07498.1 - 0.0028 17.2 0.2 0.092 12.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EDO07498.1 - 0.0034 17.4 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_29 PF13555.1 EDO07498.1 - 0.0045 16.4 0.1 0.21 11.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Cytidylate_kin2 PF13189.1 EDO07498.1 - 0.0068 16.3 0.1 1.8 8.4 0.0 2.6 3 0 0 3 3 2 1 Cytidylate kinase-like family SKI PF01202.17 EDO07498.1 - 0.017 14.9 0.1 5.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.10 EDO07498.1 - 0.021 14.5 0.0 2.7 7.6 0.0 2.7 2 0 0 2 2 2 0 NTPase DAP3 PF10236.4 EDO07498.1 - 0.022 13.6 0.0 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 UPF0079 PF02367.12 EDO07498.1 - 0.023 14.3 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 EDO07498.1 - 0.035 13.3 0.1 2.4 7.3 0.0 3.0 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain KaiC PF06745.8 EDO07498.1 - 0.044 12.8 0.1 0.88 8.6 0.0 2.5 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 EDO07498.1 - 0.054 12.7 0.4 3.1 6.9 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 EDO07498.1 - 0.06 12.9 0.0 8.1 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EDO07498.1 - 0.066 13.5 0.0 8.8 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EDO07498.1 - 0.077 11.8 0.0 2.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein KTI12 PF08433.5 EDO07498.1 - 0.08 12.1 0.1 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ATP-synt_ab PF00006.20 EDO07498.1 - 0.093 12.2 0.0 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EDO07498.1 - 0.096 12.1 0.2 14 4.9 0.0 2.7 2 1 0 2 2 2 0 AAA-like domain AAA_11 PF13086.1 EDO07498.1 - 0.12 11.8 0.0 8.4 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EDO07498.1 - 0.13 11.7 0.0 15 5.0 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DDHD PF02862.12 EDO07499.1 - 4.2e-27 95.4 0.8 6.7e-27 94.7 0.0 1.7 2 0 0 2 2 2 1 DDHD domain Abhydrolase_1 PF00561.15 EDO07499.1 - 0.026 14.0 0.0 0.53 9.8 0.0 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDO07499.1 - 0.14 11.9 0.0 0.66 9.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Sod_Fe_C PF02777.13 EDO07500.1 - 8.3e-38 128.4 0.8 4.8e-37 126.0 0.1 2.1 3 0 0 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EDO07500.1 - 1.9e-28 98.5 1.3 1.9e-28 98.5 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain RAP PF08373.5 EDO07502.1 - 1.4e-15 56.7 0.1 3.8e-15 55.4 0.1 1.8 1 0 0 1 1 1 1 RAP domain FlhD PF05247.8 EDO07502.1 - 0.29 11.1 5.2 0.062 13.3 0.8 2.1 3 0 0 3 3 3 0 Flagellar transcriptional activator (FlhD) DnaJ PF00226.26 EDO07504.1 - 1.7e-18 66.1 0.5 3.4e-18 65.1 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 EDO07504.1 - 0.0098 15.7 0.0 0.042 13.7 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.4 EDO07504.1 - 0.083 12.8 1.0 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDO07504.1 - 0.29 10.9 2.4 0.59 10.0 0.2 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat SPRY PF00622.23 EDO07505.1 - 0.0038 17.2 0.0 0.066 13.3 0.0 2.5 2 1 0 2 2 2 1 SPRY domain CLPTM1 PF05602.7 EDO07506.1 - 1.8e-116 389.4 6.4 2.2e-116 389.1 4.4 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 EDO07506.1 - 5.2e-08 32.3 1.7 0.0046 16.4 0.1 3.0 2 0 0 2 2 2 2 PQ loop repeat DUF1240 PF06836.7 EDO07506.1 - 5.3 7.3 18.8 2.3 8.4 2.9 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1240) Peptidase_M18 PF02127.10 EDO07507.1 - 6.3e-87 291.8 0.3 1.3e-73 247.9 0.0 2.2 1 1 1 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EDO07507.1 - 3.4e-06 26.0 0.1 0.00079 18.2 0.0 3.2 2 1 0 2 2 2 2 M42 glutamyl aminopeptidase Exo_endo_phos PF03372.18 EDO07508.1 - 7.2e-18 65.4 0.0 1.1e-17 64.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Syja_N PF02383.13 EDO07509.1 - 1.3e-61 208.1 0.0 2.2e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EDO07509.1 - 3.4e-18 66.4 0.0 5.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Helicase_C PF00271.26 EDO07510.1 - 3e-15 55.8 0.0 6.8e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO07510.1 - 1.5e-11 44.1 0.1 5.4e-11 42.2 0.0 1.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDO07510.1 - 0.043 13.9 0.8 2.8 8.1 0.0 2.9 3 1 1 4 4 4 0 AAA domain Dynactin_p22 PF07426.6 EDO07510.1 - 0.17 11.1 0.3 0.59 9.3 0.2 1.8 1 1 0 1 1 1 0 Dynactin subunit p22 GPI2 PF06432.6 EDO07512.1 - 8.1e-10 38.5 0.0 9.8e-10 38.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase HALZ PF02183.13 EDO07513.1 - 0.023 14.3 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Exo_endo_phos PF03372.18 EDO07515.1 - 2.6e-11 43.9 0.1 3.5e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Acylphosphatase PF00708.13 EDO07517.1 - 3.5e-23 81.4 0.1 3.8e-23 81.4 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase Lipocalin PF00061.18 EDO07517.1 - 0.11 12.4 0.0 11 6.0 0.0 2.1 1 1 1 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family DSPc PF00782.15 EDO07518.1 - 6.8e-09 35.4 0.1 2.7e-08 33.4 0.0 1.8 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDO07518.1 - 6.7e-07 28.8 0.0 1.5e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DUF1411 PF07199.6 EDO07519.1 - 0.004 16.6 0.1 0.0071 15.8 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1411) DEP PF00610.16 EDO07519.1 - 0.035 13.8 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1411 PF07199.6 EDO07520.1 - 6.3e-05 22.4 0.0 0.22 10.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1411) AP2 PF00847.15 EDO07521.1 - 0.00017 21.6 1.6 0.057 13.5 0.4 2.5 2 0 0 2 2 2 2 AP2 domain DUF2175 PF09943.4 EDO07521.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) TPR_11 PF13414.1 EDO07522.1 - 1.9e-08 33.8 0.3 4.3e-08 32.6 0.1 1.7 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EDO07522.1 - 3.6e-06 26.3 2.9 0.0009 18.7 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDO07522.1 - 1.2e-05 24.7 2.4 0.07 13.0 0.1 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EDO07522.1 - 0.0017 18.4 1.0 0.0071 16.4 0.3 2.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EDO07522.1 - 0.019 15.6 0.0 0.083 13.5 0.0 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDO07522.1 - 0.028 14.1 1.9 6.3 6.8 0.3 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO07522.1 - 0.038 13.9 0.2 2.1 8.3 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDO07522.1 - 0.058 13.2 0.0 32 4.6 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat RPA_interact_N PF14766.1 EDO07522.1 - 0.22 10.9 3.7 12 5.5 0.7 2.6 3 0 0 3 3 3 0 Replication protein A interacting N-terminal ubiquitin PF00240.18 EDO07523.1 - 5.1e-19 67.4 0.0 9.5e-19 66.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EDO07523.1 - 4e-10 39.2 0.1 7e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 EDO07523.1 - 0.00021 21.0 0.0 0.00069 19.3 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Ubiquitin_2 PF14560.1 EDO07523.1 - 0.00025 21.2 0.0 0.00062 19.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain ComX PF05952.7 EDO07523.1 - 0.003 17.0 8.2 0.62 9.6 0.3 3.4 3 0 0 3 3 3 2 Bacillus competence pheromone ComX DUF2407 PF10302.4 EDO07523.1 - 0.0096 16.0 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EDO07523.1 - 0.032 14.1 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 EDO07523.1 - 0.92 9.0 3.2 1 8.9 0.1 2.4 2 0 0 2 2 2 0 CUE domain XPC-binding PF09280.6 EDO07523.1 - 2 7.9 26.2 16 5.0 0.0 4.1 2 1 0 2 2 2 0 XPC-binding domain UAA PF08449.6 EDO07524.1 - 8.4e-53 179.2 17.9 1.3e-52 178.5 12.4 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EDO07524.1 - 1e-07 31.6 21.6 5e-05 22.9 7.3 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EDO07524.1 - 0.0026 17.7 1.1 0.0026 17.7 0.7 2.9 3 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EDO07524.1 - 0.0073 16.4 0.8 0.0073 16.4 0.6 4.2 3 2 1 4 4 4 1 Multidrug resistance efflux transporter DUF3671 PF12420.3 EDO07524.1 - 0.22 11.5 0.1 0.22 11.5 0.1 4.1 1 1 1 2 2 2 0 Protein of unknown function UFD1 PF03152.9 EDO07525.1 - 5.1e-33 113.6 0.0 4.5e-26 91.0 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 hemP PF10636.4 EDO07525.1 - 0.14 11.7 0.6 0.28 10.7 0.4 1.4 1 0 0 1 1 1 0 Hemin uptake protein hemP OMPdecase PF00215.19 EDO07528.1 - 1e-28 100.3 0.0 1.3e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family SNF2_N PF00176.18 EDO07529.1 - 1.5e-69 234.0 0.7 1.5e-69 234.0 0.5 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO07529.1 - 4.6e-15 55.2 0.1 1.3e-14 53.7 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IncA PF04156.9 EDO07530.1 - 0.14 11.7 0.2 0.22 11.0 0.2 1.3 1 0 0 1 1 1 0 IncA protein PLDc_2 PF13091.1 EDO07531.1 - 3.8e-11 42.8 0.0 0.00011 21.9 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EDO07531.1 - 0.0039 16.9 5.3 0.02 14.6 0.1 3.6 3 1 0 3 3 3 1 Phospholipase D Active site motif Ribosomal_L23 PF00276.15 EDO07534.1 - 3.3e-13 49.4 0.0 7.8e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 ACDC PF14733.1 EDO07535.1 - 9.2e-19 67.3 0.0 1.5e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 EDO07535.1 - 3.9e-08 33.3 0.8 1.8e-07 31.1 0.6 2.2 2 0 0 2 2 2 1 AP2 domain Toxin_56 PF15534.1 EDO07536.1 - 0.063 13.7 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 Putative toxin 56 DUF2721 PF11026.3 EDO07536.1 - 0.46 10.1 3.8 0.79 9.3 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DNA_gyraseB PF00204.20 EDO07537.1 - 9.4e-43 145.4 0.3 1.7e-42 144.5 0.2 1.5 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EDO07537.1 - 4e-27 94.1 0.0 1.3e-26 92.5 0.0 1.9 1 1 0 1 1 1 1 Toprim domain DNA_gyraseB_C PF00986.16 EDO07537.1 - 7.7e-26 89.6 1.2 1.5e-25 88.7 0.9 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.21 EDO07537.1 - 3.1e-11 42.9 0.0 3.3e-10 39.6 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EDO07537.1 - 0.005 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim_4 PF13662.1 EDO07537.1 - 0.01 15.8 0.0 0.42 10.6 0.0 2.4 2 0 0 2 2 2 0 Toprim domain DUF3701 PF12482.3 EDO07537.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Phage integrase protein HK PF02110.10 EDO07538.1 - 0.0017 17.5 0.2 0.0031 16.7 0.1 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Peptidase_S41 PF03572.13 EDO07538.1 - 0.046 13.1 0.2 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S41 Peptidase_M41 PF01434.13 EDO07539.1 - 1.7e-67 227.0 0.4 2.4e-67 226.5 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EDO07539.1 - 1.5e-43 148.1 0.0 2.7e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDO07539.1 - 4.5e-07 29.1 0.5 2.8e-06 26.5 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EDO07539.1 - 3.4e-06 27.8 0.0 1.1e-05 26.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EDO07539.1 - 6.1e-06 25.9 0.0 2.3e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDO07539.1 - 8.5e-06 25.9 0.6 0.0018 18.4 0.0 3.5 2 1 1 3 3 2 1 AAA domain TIP49 PF06068.8 EDO07539.1 - 9.6e-05 21.2 0.0 0.00018 20.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EDO07539.1 - 0.00035 20.6 1.3 0.0026 17.7 0.0 2.5 2 1 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EDO07539.1 - 0.00038 19.9 0.0 0.00072 19.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EDO07539.1 - 0.00055 19.8 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EDO07539.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EDO07539.1 - 0.0016 18.4 1.0 0.0063 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDO07539.1 - 0.0016 18.2 0.0 0.0044 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDO07539.1 - 0.0017 17.4 0.5 0.0045 16.0 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EDO07539.1 - 0.0024 17.5 2.5 0.0045 16.7 0.3 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EDO07539.1 - 0.0028 17.5 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EDO07539.1 - 0.0029 17.2 1.1 0.044 13.4 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AAA_25 PF13481.1 EDO07539.1 - 0.0036 16.7 1.0 0.092 12.1 0.2 2.5 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 EDO07539.1 - 0.0095 14.8 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 EDO07539.1 - 0.037 13.6 0.1 0.88 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EDO07539.1 - 0.039 13.1 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 EDO07539.1 - 0.075 12.4 0.0 0.21 11.0 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 EDO07539.1 - 0.079 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain BetR PF08667.5 EDO07539.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 BetR domain ABC_tran PF00005.22 EDO07539.1 - 0.14 12.4 1.0 0.97 9.7 0.0 2.8 4 0 0 4 4 3 0 ABC transporter Vps16_N PF04841.8 EDO07540.1 - 2e-19 69.4 0.0 1.6e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.7 EDO07540.1 - 1.4e-08 34.0 0.0 0.0014 17.6 0.0 2.1 2 0 0 2 2 2 2 Vps16, C-terminal region WD40 PF00400.27 EDO07541.1 - 1.7e-28 97.4 12.8 2.7e-08 33.3 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Ribosomal_L1 PF00687.16 EDO07541.1 - 3.9e-15 55.7 0.0 6e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family eIF2A PF08662.6 EDO07541.1 - 4.7e-06 26.4 0.0 0.0038 16.9 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EDO07541.1 - 0.044 11.6 0.0 0.46 8.2 0.0 2.3 3 0 0 3 3 3 0 IKI3 family SH3_3 PF08239.6 EDO07543.1 - 0.051 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Macoilin PF09726.4 EDO07543.1 - 0.98 7.6 10.0 1.2 7.3 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Rpp20 PF12328.3 EDO07545.1 - 2.1e-07 30.6 0.0 0.021 14.4 0.0 2.6 2 1 0 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EDO07545.1 - 0.028 14.0 0.0 0.11 12.1 0.0 2.0 2 1 0 2 2 2 0 Alba RPAP2_Rtr1 PF04181.8 EDO07547.1 - 6.6e-13 48.5 0.4 1.3e-12 47.6 0.2 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family CofC PF01983.11 EDO07547.1 - 0.04 12.8 0.0 0.085 11.8 0.0 1.5 1 0 0 1 1 1 0 Guanylyl transferase CofC like Cpn60_TCP1 PF00118.19 EDO07548.1 - 3.2e-139 464.6 4.7 3.6e-139 464.5 3.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ADH_zinc_N PF00107.21 EDO07548.1 - 0.0046 16.5 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PrpR_N PF06506.6 EDO07548.1 - 0.018 14.4 0.1 0.066 12.6 0.1 2.1 1 0 0 1 1 1 0 Propionate catabolism activator zf-CCHC PF00098.18 EDO07550.1 - 1.6e-05 24.5 3.3 2.8e-05 23.8 2.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EDO07550.1 - 0.57 9.8 3.7 1.1 8.9 2.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-C3HC4_3 PF13920.1 EDO07552.1 - 1.3e-13 50.3 16.9 2.2e-13 49.6 11.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO07552.1 - 5.2e-07 29.5 16.2 1.1e-06 28.5 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO07552.1 - 2.5e-05 24.0 16.4 5.9e-05 22.8 11.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EDO07552.1 - 0.017 14.8 14.6 0.031 14.0 10.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.9 EDO07552.1 - 0.31 10.5 9.0 0.59 9.6 6.2 1.5 1 0 0 1 1 1 0 P-11 zinc finger DZR PF12773.2 EDO07552.1 - 3.1 7.6 9.4 7.7 6.4 6.5 1.6 1 1 0 1 1 1 0 Double zinc ribbon PqiA PF04403.8 EDO07554.1 - 6.2e-09 35.6 16.3 1.4e-07 31.2 3.8 3.7 2 2 0 2 2 2 2 Paraquat-inducible protein A Josephin PF02099.12 EDO07554.1 - 0.019 14.6 0.7 0.034 13.7 0.5 1.3 1 0 0 1 1 1 0 Josephin Myosin_head PF00063.16 EDO07555.1 - 2.6e-165 551.3 0.0 6.4e-165 550.0 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) RCC1 PF00415.13 EDO07555.1 - 4.2e-20 71.6 10.9 4.9e-10 39.4 0.1 5.0 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDO07555.1 - 1.7e-14 52.9 34.8 7e-05 22.3 0.9 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.22 EDO07555.1 - 3e-12 45.0 29.0 6.5e-05 22.2 0.2 6.9 7 0 0 7 7 7 4 IQ calmodulin-binding motif AAA_22 PF13401.1 EDO07555.1 - 0.0051 16.9 0.0 0.022 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDO07555.1 - 0.023 14.6 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EDO07555.1 - 0.049 12.8 0.0 0.31 10.2 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EDO07555.1 - 0.17 10.9 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Myosin_N PF02736.14 EDO07555.1 - 0.32 10.7 0.4 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Pkinase PF00069.20 EDO07557.1 - 2.2e-20 72.9 0.8 3.3e-19 69.0 0.5 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO07557.1 - 9.1e-06 24.9 1.1 4.5e-05 22.6 0.7 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase ArfGap PF01412.13 EDO07558.1 - 3.8e-31 107.2 0.6 8.7e-31 106.1 0.0 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Pro_isomerase PF00160.16 EDO07559.1 - 4.1e-36 124.5 0.2 4.7e-36 124.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arg_repressor_C PF02863.13 EDO07559.1 - 0.15 11.5 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain PseudoU_synth_1 PF01416.15 EDO07560.1 - 9.7e-29 99.8 0.0 6.5e-13 49.0 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF3687 PF12459.3 EDO07561.1 - 7.9 5.8 10.1 1.9 7.8 0.2 3.7 3 0 0 3 3 3 0 D-Ala-teichoic acid biosynthesis protein DUF2207 PF09972.4 EDO07563.1 - 5.2e-05 22.0 0.4 5.8e-05 21.8 0.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) MFS_Mycoplasma PF07672.8 EDO07563.1 - 0.0051 16.0 1.6 0.0073 15.5 1.1 1.3 1 0 0 1 1 1 1 Mycoplasma MFS transporter DUF4519 PF15012.1 EDO07563.1 - 0.0096 15.8 0.7 0.08 12.8 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4519) Tic20 PF09685.5 EDO07563.1 - 0.012 15.5 2.2 0.097 12.6 1.1 2.2 2 0 0 2 2 2 0 Tic20-like protein DUF3671 PF12420.3 EDO07563.1 - 0.028 14.3 4.4 0.047 13.6 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2269 PF10027.4 EDO07563.1 - 0.059 13.1 0.7 0.19 11.5 0.2 1.9 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) EXS PF03124.9 EDO07563.1 - 0.07 12.1 0.5 0.073 12.0 0.3 1.2 1 1 0 1 1 1 0 EXS family Peroxin-3 PF04882.7 EDO07563.1 - 0.091 11.4 0.4 0.15 10.6 0.1 1.5 2 0 0 2 2 2 0 Peroxin-3 DUF3357 PF11837.3 EDO07563.1 - 0.096 12.5 0.1 0.95 9.3 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF912 PF06024.7 EDO07563.1 - 0.1 12.6 1.5 0.1 12.6 0.1 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Amnionless PF14828.1 EDO07563.1 - 0.14 10.6 0.4 0.19 10.1 0.1 1.3 1 1 0 1 1 1 0 Amnionless TMEM192 PF14802.1 EDO07563.1 - 0.23 10.2 1.8 0.19 10.5 0.3 1.6 2 0 0 2 2 2 0 TMEM192 family Choline_transpo PF04515.7 EDO07563.1 - 0.25 10.0 7.6 0.37 9.4 3.4 2.0 1 1 1 2 2 2 0 Plasma-membrane choline transporter DUF4293 PF14126.1 EDO07563.1 - 0.67 9.8 3.5 0.64 9.9 0.8 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) DUF2852 PF11014.3 EDO07563.1 - 1 9.3 3.6 1.7 8.6 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2852) zf-DHHC PF01529.15 EDO07563.1 - 1.7 8.0 5.1 1.2 8.4 2.4 1.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF962 PF06127.6 EDO07564.1 - 0.017 14.9 0.0 0.17 11.7 0.0 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF962) DUF2231 PF09990.4 EDO07564.1 - 0.32 11.3 18.8 0.42 10.9 1.7 4.1 2 1 2 4 4 4 0 Predicted membrane protein (DUF2231) VESA1_N PF12785.2 EDO07565.1 - 5e-78 263.1 33.4 6.3e-78 262.7 23.1 1.0 1 0 0 1 1 1 1 Variant erythrocyte surface antigen-1 F-box-like_2 PF13013.1 EDO07566.1 - 0.0013 18.4 0.0 0.0042 16.7 0.0 1.8 1 1 1 2 2 2 1 F-box-like domain Malate_DH PF12434.3 EDO07566.1 - 5.4 6.8 5.5 2.1 8.1 0.2 2.6 3 0 0 3 3 3 0 Malate dehydrogenase enzyme VESA1_N PF12785.2 EDO07567.1 - 1.6e-09 37.2 30.2 2e-05 23.7 17.4 2.8 1 1 1 2 2 2 2 Variant erythrocyte surface antigen-1 SIT PF15330.1 EDO07568.1 - 0.22 11.7 3.3 0.17 12.0 0.5 2.1 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF3357 PF11837.3 EDO07568.1 - 5.4 6.9 8.2 12 5.7 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Methyltransf_28 PF02636.12 EDO07571.1 - 0.1 12.0 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase VESA1_N PF12785.2 EDO07573.1 - 8.9e-183 608.4 30.8 8.9e-183 608.4 21.3 2.6 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 ApoLp-III PF07464.6 EDO07573.1 - 0.011 15.7 1.9 0.011 15.7 1.3 2.5 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) AAA_13 PF13166.1 EDO07573.1 - 0.036 12.5 1.4 0.055 11.9 0.9 1.2 1 0 0 1 1 1 0 AAA domain Glutaredoxin2_C PF04399.8 EDO07573.1 - 0.051 13.1 0.5 9.7 5.7 0.0 2.6 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain T4SS PF07996.6 EDO07573.1 - 0.063 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion system proteins DUF4398 PF14346.1 EDO07573.1 - 0.078 13.0 3.8 0.64 10.0 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Baculo_PEP_C PF04513.7 EDO07573.1 - 1.1 9.1 2.2 9.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 EDO07573.1 - 3.5 6.1 8.6 1.4e+02 0.9 5.9 2.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1542 PF07564.6 EDO07573.1 - 3.6 7.6 7.3 0.44 10.5 1.1 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) Prefoldin_2 PF01920.15 EDO07573.1 - 6.9 6.4 13.0 11 5.8 1.1 2.6 2 0 0 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.6 EDO07573.1 - 7.9 6.4 6.7 5.2 7.0 0.5 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) F-box-like_2 PF13013.1 EDO07574.1 - 3.9e-22 78.0 3.7 4.2e-21 74.7 0.8 2.4 1 1 2 3 3 3 1 F-box-like domain NOT2_3_5 PF04153.13 EDO07574.1 - 0.064 13.1 0.4 0.11 12.3 0.3 1.4 1 1 0 1 1 1 0 NOT2 / NOT3 / NOT5 family DUF3420 PF11900.3 EDO07574.1 - 0.076 13.1 0.7 7 6.8 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3420) Cyto_ox_2 PF02322.10 EDO07575.1 - 0.48 9.5 29.6 0.17 11.0 3.8 3.1 2 1 1 3 3 3 0 Cytochrome oxidase subunit II DUF1469 PF07332.6 EDO07576.1 - 0.0023 17.6 0.6 0.0041 16.8 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) Na_H_Exchanger PF00999.16 EDO07576.1 - 0.0091 14.5 0.8 0.013 14.0 0.6 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family UPF0104 PF03706.8 EDO07576.1 - 0.021 14.1 1.1 0.021 14.1 0.8 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0104) DUF2207 PF09972.4 EDO07576.1 - 0.026 13.1 0.7 0.028 13.0 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2567 PF10821.3 EDO07576.1 - 0.051 13.1 0.1 0.056 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) SepZ PF06066.6 EDO07576.1 - 0.068 13.1 0.7 0.092 12.7 0.5 1.2 1 0 0 1 1 1 0 SepZ DUF4199 PF13858.1 EDO07576.1 - 0.075 12.9 0.3 0.075 12.9 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF4229 PF14012.1 EDO07576.1 - 0.11 12.4 1.8 0.16 11.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) TatC PF00902.13 EDO07576.1 - 0.12 11.7 1.2 2.2 7.6 0.0 2.1 1 1 1 2 2 2 0 Sec-independent protein translocase protein (TatC) ABC2_membrane_5 PF13346.1 EDO07576.1 - 0.81 8.9 6.2 0.14 11.4 2.0 1.4 2 0 0 2 2 2 0 ABC-2 family transporter protein MLANA PF14991.1 EDO07576.1 - 0.9 9.5 3.2 0.87 9.6 0.2 1.9 1 1 1 2 2 2 0 Protein melan-A O-antigen_lig PF13425.1 EDO07576.1 - 2.2 8.2 8.1 4.2 7.3 1.3 2.0 1 1 1 2 2 2 0 O-antigen ligase like membrane protein P12 PF12669.2 EDO07576.1 - 2.7 8.2 11.3 1.3 9.2 0.2 2.5 3 0 0 3 3 3 0 Virus attachment protein p12 family PLDc_N PF13396.1 EDO07576.1 - 6.1 6.5 7.6 0.21 11.2 1.2 1.7 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal Orbi_NS3 PF01616.11 EDO07577.1 - 0.2 10.6 0.2 2.1 7.2 0.0 2.4 2 1 0 2 2 2 0 Orbivirus NS3 NPCC PF08058.6 EDO07577.1 - 0.2 11.4 0.0 0.2 11.4 0.0 2.0 3 0 0 3 3 3 0 Nuclear pore complex component T_cell_tran_alt PF15128.1 EDO07577.1 - 0.32 10.4 5.4 1.6 8.2 0.0 3.1 2 1 1 3 3 3 0 T-cell leukemia translocation-altered CoA_binding_3 PF13727.1 EDO07577.1 - 1.5 8.6 7.3 0.093 12.5 0.4 2.2 2 0 0 2 2 2 0 CoA-binding domain VESA1_N PF12785.2 EDO07578.1 - 1.2e-22 80.5 25.4 6.1e-22 78.2 6.6 4.3 2 1 1 3 3 3 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO07579.1 - 9.7e-211 700.6 21.5 9.7e-211 700.6 14.9 2.7 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 Baculo_PEP_C PF04513.7 EDO07579.1 - 0.00015 21.5 3.2 0.00033 20.4 1.3 2.3 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus GTPase_Cys_C PF12631.2 EDO07579.1 - 0.00029 21.1 0.3 0.01 16.2 0.1 3.4 5 1 0 5 5 5 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MscS_porin PF12795.2 EDO07579.1 - 0.18 11.1 0.4 0.37 10.0 0.3 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ApoLp-III PF07464.6 EDO07579.1 - 0.72 9.8 5.7 0.74 9.8 2.0 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Rab5-bind PF09311.6 EDO07579.1 - 0.87 9.4 4.9 2.5 7.9 0.8 2.4 2 0 0 2 2 2 0 Rabaptin-like protein COX17 PF05051.8 EDO07581.1 - 7e-21 73.9 7.6 8.6e-21 73.7 5.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) BCNT PF07572.7 EDO07582.1 - 6.4e-11 42.0 0.6 6.4e-11 42.0 0.4 2.3 3 0 0 3 3 3 1 Bucentaur or craniofacial development Polyketide_cyc PF03364.15 EDO07585.1 - 4.9e-06 26.5 0.0 5.9e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DEAD PF00270.24 EDO07586.1 - 5e-47 159.5 0.0 2.3e-45 154.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO07586.1 - 7e-26 89.9 1.7 1.5e-25 88.8 0.6 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO07586.1 - 0.00025 20.9 0.0 0.00061 19.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDO07586.1 - 0.00062 18.6 0.0 0.00089 18.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 EDO07586.1 - 0.065 11.6 0.1 0.9 7.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) Spt5-NGN PF03439.8 EDO07587.1 - 1.4e-19 69.5 0.0 8.4e-19 67.1 0.0 2.4 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EDO07587.1 - 2.6e-17 63.2 12.4 7e-17 61.8 8.6 1.8 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EDO07587.1 - 1e-12 47.2 31.0 0.0016 18.0 1.7 7.6 8 0 0 8 8 8 4 KOW motif DUF3912 PF13051.1 EDO07587.1 - 9.3e-05 22.0 1.2 0.42 10.4 0.0 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3912) YajC PF02699.10 EDO07587.1 - 0.21 11.2 11.4 10 5.9 0.0 5.0 5 1 0 5 5 5 0 Preprotein translocase subunit NIF PF03031.13 EDO07589.1 - 2.3e-19 69.6 0.8 1.5e-18 66.9 0.2 2.5 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EDO07589.1 - 0.0061 16.7 0.1 0.017 15.3 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SAP18 PF06487.7 EDO07591.1 - 1.2e-08 34.7 0.1 4.3e-08 32.9 0.1 2.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Sld5 PF05916.6 EDO07592.1 - 3.6e-11 43.3 0.2 8.6e-11 42.0 0.1 1.7 1 0 0 1 1 1 1 GINS complex protein Ribosomal_S8e PF01201.17 EDO07593.1 - 1.4e-37 128.8 9.4 7.7e-37 126.3 6.5 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e DUF1048 PF06304.6 EDO07593.1 - 0.12 12.6 0.2 0.12 12.6 0.2 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1048) DUF3959 PF13105.1 EDO07593.1 - 1.1 8.5 13.3 0.028 13.7 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Peptidase_S24 PF00717.18 EDO07594.1 - 1.2e-10 40.9 0.1 1.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like DUF2269 PF10027.4 EDO07594.1 - 0.033 13.9 0.6 0.053 13.2 0.4 1.5 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) CPW_WPC PF09717.5 EDO07595.1 - 2.6e-47 159.2 35.1 4.3e-15 56.0 1.9 6.1 6 0 0 6 6 6 6 Plasmodium falciparum domain of unknown function (CPW_WPC) Bac_surface_Ag PF01103.18 EDO07597.1 - 1.4e-13 51.0 0.1 1.8e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 Surface antigen Surf_Ag_VNR PF07244.10 EDO07597.1 - 0.0029 17.9 0.1 0.0066 16.8 0.0 1.6 1 0 0 1 1 1 1 Surface antigen variable number repeat Proteasome PF00227.21 EDO07598.1 - 2.5e-56 189.9 0.0 4.6e-56 189.1 0.0 1.4 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO07598.1 - 2e-09 36.5 0.2 4.8e-09 35.3 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature MACPF PF01823.14 EDO07599.1 - 2.4e-21 76.4 0.1 1.6e-20 73.6 0.0 2.0 1 1 0 1 1 1 1 MAC/Perforin domain RNA_pol_A_bac PF01000.21 EDO07602.1 - 0.0074 16.4 1.7 2.7 8.1 0.1 2.9 3 0 0 3 3 3 2 RNA polymerase Rpb3/RpoA insert domain GTP_EFTU PF00009.22 EDO07603.1 - 3.6e-54 183.0 0.0 5.7e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EDO07603.1 - 2e-29 101.2 0.1 3.9e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EDO07603.1 - 4.1e-29 100.5 0.0 1.4e-28 98.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EDO07603.1 - 1.2e-23 82.7 0.1 3.1e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDO07603.1 - 2.5e-10 40.2 0.0 7e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 FAD_binding_3 PF01494.14 EDO07604.1 - 0.12 11.3 1.0 0.18 10.8 0.7 1.1 1 0 0 1 1 1 0 FAD binding domain DUF1754 PF08555.5 EDO07605.1 - 1.1e-09 38.7 0.8 1.1e-09 38.7 0.5 3.2 3 0 0 3 3 3 1 Eukaryotic family of unknown function (DUF1754) DUF1604 PF07713.8 EDO07605.1 - 7.5e-06 25.6 0.0 7.5e-06 25.6 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) Synaptobrevin PF00957.16 EDO07605.1 - 0.016 14.7 2.6 0.05 13.2 1.8 1.8 1 0 0 1 1 1 0 Synaptobrevin TCTP PF00838.12 EDO07605.1 - 0.61 10.0 7.0 0.16 11.9 1.5 2.2 2 0 0 2 2 2 0 Translationally controlled tumour protein C2-set PF05790.10 EDO07606.1 - 0.088 12.7 0.1 0.62 10.0 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin C2-set domain UbiA PF01040.13 EDO07607.1 - 1.9e-26 92.8 13.1 2.5e-26 92.4 9.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family MACPF PF01823.14 EDO07608.1 - 1.6e-81 273.0 20.5 6.9e-28 97.7 0.3 3.3 3 0 0 3 3 3 3 MAC/Perforin domain OHA PF14418.1 EDO07609.1 - 1.5e-23 82.0 0.0 4.5e-23 80.5 0.0 1.9 2 0 0 2 2 2 1 OST-HTH Associated domain OST-HTH PF12872.2 EDO07609.1 - 2.8e-06 27.0 0.6 1.2e-05 25.0 0.0 2.3 3 0 0 3 3 3 1 OST-HTH/LOTUS domain MMR_HSR1 PF01926.18 EDO07610.1 - 8.4e-21 74.0 0.0 1.3e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.17 EDO07610.1 - 9.8e-15 54.5 3.8 1.2e-12 47.8 2.6 2.2 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.13 EDO07610.1 - 1.2e-12 47.3 0.0 3.1e-12 46.0 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 EDO07610.1 - 1.5e-07 30.8 0.0 2.2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDO07610.1 - 3.5e-07 29.8 0.1 0.00011 21.6 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 EDO07610.1 - 1.3e-05 25.6 0.0 2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EDO07610.1 - 8.4e-05 21.4 0.1 0.22 10.2 0.0 2.1 2 0 0 2 2 2 2 ArgK protein SRPRB PF09439.5 EDO07610.1 - 0.00013 21.2 0.0 0.00019 20.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EDO07610.1 - 0.0095 15.5 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein NOG1 PF06858.9 EDO07610.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Dynamin_N PF00350.18 EDO07610.1 - 0.017 14.9 0.1 1 9.1 0.0 2.3 1 1 1 2 2 2 0 Dynamin family Gtr1_RagA PF04670.7 EDO07610.1 - 0.057 12.5 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region dCMP_cyt_deam_1 PF00383.17 EDO07612.1 - 5e-16 58.2 0.6 2.2e-15 56.1 0.2 1.9 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EDO07612.1 - 0.071 12.9 1.3 0.17 11.7 0.9 1.6 1 1 0 1 1 1 0 Bd3614-like deaminase Snf7 PF03357.16 EDO07613.1 - 7.2e-19 67.8 1.4 9.6e-19 67.3 1.0 1.0 1 0 0 1 1 1 1 Snf7 Plus-3 PF03126.13 EDO07613.1 - 0.043 13.8 0.1 0.17 11.9 0.0 1.9 1 1 1 2 2 2 0 Plus-3 domain Ins_beta PF03488.9 EDO07613.1 - 0.073 12.8 0.7 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type DEAD PF00270.24 EDO07614.1 - 1.2e-32 112.7 0.2 2.8e-32 111.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO07614.1 - 1.1e-17 63.5 0.0 1.6e-15 56.6 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDO07614.1 - 0.0037 16.1 0.3 0.0037 16.1 0.2 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain YqzH PF14164.1 EDO07614.1 - 0.016 15.1 0.8 0.077 12.9 0.2 2.5 2 0 0 2 2 2 0 YqzH-like protein POP1 PF06978.6 EDO07615.1 - 3.1e-44 150.8 18.7 1.1e-41 142.5 11.4 3.0 2 1 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EDO07615.1 - 1.3e-10 41.0 0.0 2.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain eIF-3_zeta PF05091.7 EDO07617.1 - 1e-179 598.5 0.0 1.1e-179 598.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Patatin PF01734.17 EDO07618.1 - 1.7e-24 86.8 0.6 3.5e-24 85.8 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase DUF2090 PF09863.4 EDO07618.1 - 0.0048 15.7 0.2 0.068 11.9 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2090) zf-HC5HC2H_2 PF13832.1 EDO07619.1 - 2.6e-17 62.7 29.5 6.9e-11 42.1 6.6 4.5 3 1 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EDO07619.1 - 6.3e-13 48.6 25.3 1.9e-08 34.3 7.4 5.1 5 0 0 5 5 5 2 PHD-like zinc-binding domain PHD PF00628.24 EDO07619.1 - 1.9e-06 27.4 4.4 1.9e-06 27.4 3.1 8.5 7 2 1 8 8 8 2 PHD-finger Rhomboid PF01694.17 EDO07620.1 - 2.6e-23 82.6 13.0 1.1e-15 57.8 2.0 2.8 3 0 0 3 3 3 2 Rhomboid family DUF1751 PF08551.5 EDO07620.1 - 0.14 12.5 0.1 0.14 12.5 0.0 2.3 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) Spc97_Spc98 PF04130.8 EDO07621.1 - 0.06 11.6 1.5 0.11 10.8 0.1 1.9 2 0 0 2 2 2 0 Spc97 / Spc98 family Ribosomal_L15e PF00827.12 EDO07622.1 - 1.9e-94 314.5 12.6 2.2e-94 314.3 8.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 Clat_adaptor_s PF01217.15 EDO07623.1 - 1.8e-09 37.4 0.1 7.7e-09 35.4 0.1 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain AP2 PF00847.15 EDO07624.1 - 2.5e-15 56.3 1.9 5.3e-15 55.3 1.3 1.6 1 0 0 1 1 1 1 AP2 domain HA PF03457.9 EDO07624.1 - 0.061 13.4 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 Helicase associated domain Poxvirus_B22R_N PF13169.1 EDO07624.1 - 0.1 12.7 1.8 0.26 11.4 0.0 2.3 2 1 1 3 3 3 0 Poxvirus B22R protein N-terminal DAO PF01266.19 EDO07625.1 - 4.4e-21 75.1 0.0 5.7e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.10 EDO07625.1 - 7.7e-21 73.8 0.0 5.1e-20 71.1 0.0 1.8 1 1 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox_3 PF13738.1 EDO07625.1 - 4.1e-07 30.2 0.0 0.0019 18.2 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EDO07625.1 - 0.013 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 EDO07625.1 - 0.021 14.8 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Peptidase_M4_C PF02868.10 EDO07625.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain NUDIX PF00293.23 EDO07629.1 - 7e-09 35.4 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Zip PF02535.17 EDO07630.1 - 2e-36 125.5 5.0 2e-36 125.5 3.4 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter DUF95 PF01944.12 EDO07630.1 - 7.9 6.0 14.2 0.92 9.1 0.7 3.2 3 1 0 3 3 3 0 Integral membrane protein DUF95 NUDIX PF00293.23 EDO07631.1 - 2e-12 46.9 0.0 3.2e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF1456 PF07308.8 EDO07631.1 - 0.07 13.1 0.2 16 5.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) HD_assoc PF13286.1 EDO07632.1 - 0.4 10.9 6.9 0.84 9.9 0.0 3.3 4 0 0 4 4 4 0 Phosphohydrolase-associated domain PGM_PMM_I PF02878.11 EDO07633.1 - 9.4e-16 57.5 0.1 1.8e-08 33.9 0.0 2.5 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EDO07633.1 - 6.6e-09 36.0 0.0 2.5e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EDO07633.1 - 7.7e-09 35.4 0.1 4e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain VESA1_N PF12785.2 EDO07634.1 - 2.7e-31 109.0 15.5 2.5e-14 53.1 0.1 3.3 2 1 1 3 3 3 3 Variant erythrocyte surface antigen-1 Activator-TraM PF11657.3 EDO07634.1 - 0.27 10.7 1.2 0.67 9.4 0.8 1.7 1 1 0 1 1 1 0 Transcriptional activator TraM F-box-like_2 PF13013.1 EDO07636.1 - 0.098 12.3 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 F-box-like domain VESA1_N PF12785.2 EDO07637.1 - 1.6e-20 73.5 10.0 1.5e-11 43.9 0.1 4.4 3 1 1 5 5 5 3 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO07638.1 - 4.3e-192 639.1 23.0 3.2e-122 408.8 0.9 3.4 3 1 1 4 4 3 2 Variant erythrocyte surface antigen-1 GTPase_Cys_C PF12631.2 EDO07638.1 - 0.023 15.0 2.8 0.089 13.2 0.9 2.8 3 0 0 3 3 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE EzrA PF06160.7 EDO07638.1 - 0.03 12.5 6.0 0.045 11.9 4.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA IncA PF04156.9 EDO07638.1 - 0.052 13.1 1.4 0.12 11.9 1.0 1.5 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 EDO07638.1 - 0.073 11.7 9.4 0.14 10.8 6.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2580 PF10824.3 EDO07638.1 - 0.17 12.2 0.1 0.53 10.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2580) Mnd1 PF03962.10 EDO07638.1 - 0.17 11.5 7.5 0.37 10.4 5.2 1.6 1 0 0 1 1 1 0 Mnd1 family APG6 PF04111.7 EDO07638.1 - 0.17 10.8 7.4 0.33 9.9 5.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Baculo_PEP_C PF04513.7 EDO07638.1 - 0.23 11.2 3.4 0.7 9.7 0.4 3.1 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4175 PF13779.1 EDO07638.1 - 0.23 9.1 3.9 0.35 8.5 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Sec8_exocyst PF04048.9 EDO07638.1 - 0.72 9.4 5.3 0.18 11.4 1.0 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF3584 PF12128.3 EDO07638.1 - 1 6.5 6.8 1.4 6.1 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RRF PF01765.14 EDO07638.1 - 1.4 8.3 8.1 3 7.2 5.6 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Bap31 PF05529.7 EDO07638.1 - 4.4 6.7 7.9 12 5.2 5.5 1.7 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1664 PF07889.7 EDO07638.1 - 6.7 6.5 10.1 27 4.5 3.9 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DNA_pol_B_2 PF03175.8 EDO07639.1 - 0.013 14.2 0.6 0.018 13.7 0.4 1.3 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Baculo_LEF-3 PF05847.6 EDO07640.1 - 0.04 12.8 0.6 0.051 12.4 0.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) Abi PF02517.11 EDO07641.1 - 4e-12 46.1 3.9 4e-12 46.1 2.7 2.5 2 1 0 2 2 2 1 CAAX protease self-immunity Lyase_1 PF00206.15 EDO07643.1 - 3.9e-40 137.9 0.0 5.1e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.6 EDO07643.1 - 1.7e-36 124.5 0.0 3e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Ribosomal_S9 PF00380.14 EDO07644.1 - 4.9e-25 88.1 0.0 9.2e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ras PF00071.17 EDO07645.1 - 4.5e-62 208.2 2.5 5.4e-62 207.9 1.7 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO07645.1 - 4.2e-22 78.8 0.6 8e-22 77.9 0.4 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO07645.1 - 4.6e-18 65.0 0.3 5.9e-18 64.7 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDO07645.1 - 7.4e-07 28.5 0.5 1.1e-06 28.0 0.3 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO07645.1 - 9.9e-06 25.1 0.9 0.00018 21.0 0.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EDO07645.1 - 1.2e-05 24.6 0.4 1.7e-05 24.1 0.3 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EDO07645.1 - 8.6e-05 22.4 0.4 0.00017 21.5 0.2 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EDO07645.1 - 0.00034 20.2 0.2 0.0046 16.5 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EDO07645.1 - 0.00037 20.6 0.1 0.0079 16.3 0.0 2.2 1 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EDO07645.1 - 0.0078 15.4 0.2 0.029 13.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EDO07645.1 - 0.0088 16.3 0.8 0.019 15.2 0.6 1.8 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EDO07645.1 - 0.0096 15.9 0.1 0.077 12.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EDO07645.1 - 0.024 14.0 0.5 3.8 6.9 0.0 2.3 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EDO07645.1 - 0.028 14.0 0.6 0.063 12.8 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EDO07645.1 - 0.03 13.8 0.1 0.076 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain CPT PF07931.7 EDO07645.1 - 0.03 13.9 0.1 0.069 12.7 0.0 1.6 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 EDO07645.1 - 0.05 14.4 0.1 0.083 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EDO07645.1 - 0.051 13.2 2.6 1 8.9 1.8 2.0 1 1 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 EDO07645.1 - 0.054 12.9 0.2 0.17 11.3 0.2 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EDO07645.1 - 0.054 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_10 PF12846.2 EDO07645.1 - 0.071 12.5 0.6 0.31 10.4 0.0 1.9 1 1 0 2 2 2 0 AAA-like domain PRK PF00485.13 EDO07645.1 - 0.072 12.6 0.2 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 EDO07645.1 - 0.089 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.1 EDO07645.1 - 0.11 12.3 1.1 0.22 11.4 0.8 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EDO07645.1 - 0.61 10.3 5.0 2.9 8.1 3.6 1.8 1 1 0 1 1 1 0 AAA domain CBS PF00571.23 EDO07646.1 - 0.00038 20.1 0.0 4.6 7.1 0.1 3.6 4 0 0 4 4 4 3 CBS domain SnoaL_3 PF13474.1 EDO07647.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain Microtub_assoc PF07989.6 EDO07648.1 - 0.0063 16.3 0.4 0.013 15.2 0.3 1.6 1 0 0 1 1 1 1 Microtubule associated GAS PF13851.1 EDO07648.1 - 0.046 12.9 0.9 0.08 12.1 0.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DASH_Dad3 PF08656.5 EDO07648.1 - 0.064 12.9 0.5 0.17 11.5 0.3 1.8 1 1 0 1 1 1 0 DASH complex subunit Dad3 DUF972 PF06156.8 EDO07648.1 - 0.21 11.9 1.3 0.27 11.6 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EDO07648.1 - 0.75 9.6 5.0 1.6 8.5 3.5 1.5 1 0 0 1 1 1 0 Basic region leucine zipper NUC153 PF08159.7 EDO07652.1 - 2.1e-06 27.1 6.4 0.00013 21.5 0.5 3.5 2 0 0 2 2 2 2 NUC153 domain Spectrin PF00435.16 EDO07654.1 - 0.0011 19.2 6.8 0.0011 19.2 4.7 7.2 2 1 6 8 8 8 1 Spectrin repeat DUF3552 PF12072.3 EDO07654.1 - 0.009 15.2 117.5 0.018 14.2 10.7 5.5 1 1 4 5 5 5 3 Domain of unknown function (DUF3552) AAA_27 PF13514.1 EDO07654.1 - 0.27 8.8 75.3 0.36 8.4 52.2 1.2 1 0 0 1 1 1 0 AAA domain Filament PF00038.16 EDO07654.1 - 1.9 7.8 100.4 0.61 9.5 11.8 3.5 1 1 1 3 3 3 0 Intermediate filament protein DUF869 PF05911.6 EDO07654.1 - 2.6 6.1 88.6 0.55 8.4 34.8 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Spc7 PF08317.6 EDO07654.1 - 5.2 5.6 100.3 0.97 8.0 22.0 4.5 2 2 2 4 4 4 0 Spc7 kinetochore protein Cpn60_TCP1 PF00118.19 EDO07655.1 - 5.8e-132 440.7 1.1 6.8e-132 440.5 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family S-AdoMet_synt_N PF00438.15 EDO07655.1 - 0.09 13.0 0.0 20 5.4 0.0 3.0 2 1 0 2 2 2 0 S-adenosylmethionine synthetase, N-terminal domain DUF4083 PF13314.1 EDO07656.1 - 0.1 12.4 0.9 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) PAT1 PF09770.4 EDO07656.1 - 0.19 9.9 14.0 0.19 9.9 9.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EDO07656.1 - 1.7 8.4 5.0 1.7 8.4 3.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CBFB_NFYA PF02045.10 EDO07659.1 - 0.00034 21.0 0.8 0.00053 20.4 0.5 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DAO PF01266.19 EDO07660.1 - 6.8e-40 137.0 0.0 1.1e-39 136.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDO07660.1 - 9.3e-11 41.2 1.2 8.3e-06 24.8 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 EDO07660.1 - 1.7e-08 33.8 0.0 0.00092 18.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EDO07660.1 - 2.7e-08 33.3 2.8 2.5e-05 23.5 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDO07660.1 - 0.00011 22.2 0.0 0.0055 16.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO07660.1 - 0.00043 20.2 0.1 0.0014 18.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EDO07660.1 - 0.0016 17.3 1.0 0.018 13.9 0.2 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EDO07660.1 - 0.017 14.2 0.0 0.041 12.9 0.0 1.6 1 0 0 1 1 1 0 Thi4 family GDI PF00996.13 EDO07660.1 - 0.051 11.8 0.4 1.3 7.2 0.0 2.5 3 0 0 3 3 3 0 GDP dissociation inhibitor zf-Mss51 PF13824.1 EDO07660.1 - 0.055 13.3 0.4 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 3HCDH_N PF02737.13 EDO07660.1 - 0.12 11.9 0.1 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GvpD PF07088.6 EDO07660.1 - 0.14 10.4 0.0 0.28 9.4 0.0 1.4 2 0 0 2 2 2 0 GvpD gas vesicle protein Lycopene_cycl PF05834.7 EDO07660.1 - 0.16 10.8 1.2 0.24 10.2 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 EDO07660.1 - 0.26 9.7 0.2 0.4 9.1 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein OSTMP1 PF09777.4 EDO07661.1 - 0.11 11.6 0.1 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Sec63 PF02889.11 EDO07662.1 - 1.1e-161 537.3 0.0 8.1e-94 314.3 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EDO07662.1 - 5e-42 143.2 0.2 7.7e-26 90.5 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO07662.1 - 1.2e-07 31.4 0.0 1.2e-06 28.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO07662.1 - 4.9e-06 26.5 0.0 4.7e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDO07662.1 - 0.0048 17.0 0.2 0.033 14.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EDO07662.1 - 0.066 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EDO07662.1 - 0.072 12.5 0.0 6.1 6.2 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein RNA_pol_Rpb2_6 PF00562.23 EDO07663.1 - 5.9e-114 380.8 0.1 8.7e-114 380.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EDO07663.1 - 4.4e-41 140.0 0.0 7e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EDO07663.1 - 2e-29 101.6 0.0 4.5e-29 100.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EDO07663.1 - 3.2e-23 81.3 0.5 6.8e-23 80.2 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.9 EDO07663.1 - 6.5e-22 77.8 0.0 1.2e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EDO07663.1 - 5.3e-18 64.5 0.1 1.4e-17 63.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EDO07663.1 - 9.3e-12 44.7 0.0 3.8e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Ribosom_S12_S23 PF00164.20 EDO07664.1 - 5e-40 135.7 0.8 5.9e-40 135.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L30_N PF08079.7 EDO07665.1 - 5.2e-18 64.8 12.4 8.2e-18 64.1 8.6 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EDO07665.1 - 1.3e-16 59.9 2.6 4.7e-16 58.1 1.5 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e EB1 PF03271.12 EDO07666.1 - 1.6e-09 37.6 0.2 5.4e-09 35.9 0.1 1.9 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EDO07666.1 - 9.2e-09 35.3 4.8 3.1e-08 33.6 0.0 3.1 2 1 1 3 3 3 1 Calponin homology (CH) domain Filament PF00038.16 EDO07666.1 - 2.3e-05 24.0 13.5 4.1e-05 23.2 9.4 1.4 1 0 0 1 1 1 1 Intermediate filament protein DUF812 PF05667.6 EDO07666.1 - 5.8e-05 21.8 7.2 7e-05 21.5 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF869 PF05911.6 EDO07666.1 - 0.00032 19.0 7.5 0.00042 18.7 5.2 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 EDO07666.1 - 0.00056 19.1 3.4 0.00096 18.4 2.4 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EDO07666.1 - 0.0013 18.5 9.9 0.0021 17.8 6.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PspA_IM30 PF04012.7 EDO07666.1 - 0.0018 17.6 12.1 0.0029 16.9 8.0 1.6 1 1 0 1 1 1 1 PspA/IM30 family Spc7 PF08317.6 EDO07666.1 - 0.0061 15.2 12.0 0.012 14.2 8.3 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein WEMBL PF05701.6 EDO07666.1 - 0.0062 15.0 15.8 0.0076 14.7 5.8 2.0 1 1 1 2 2 2 1 Weak chloroplast movement under blue light Macoilin PF09726.4 EDO07666.1 - 0.016 13.5 9.1 0.019 13.2 6.3 1.1 1 0 0 1 1 1 0 Transmembrane protein MAD PF05557.8 EDO07666.1 - 0.016 13.2 14.2 0.022 12.8 9.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF641 PF04859.7 EDO07666.1 - 0.018 14.7 12.1 0.11 12.2 3.3 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.6 EDO07666.1 - 0.02 14.3 22.2 0.044 13.2 10.2 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 Kinetocho_Slk19 PF12709.2 EDO07666.1 - 0.021 14.8 13.2 0.1 12.6 2.4 3.3 1 1 1 2 2 2 0 Central kinetochore-associated Bap31 PF05529.7 EDO07666.1 - 0.026 13.9 14.0 0.026 13.9 2.1 2.7 2 1 1 3 3 2 0 B-cell receptor-associated protein 31-like APG6 PF04111.7 EDO07666.1 - 0.027 13.5 13.5 0.036 13.1 9.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF947 PF06102.7 EDO07666.1 - 0.035 13.9 14.0 0.062 13.1 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF947) ADIP PF11559.3 EDO07666.1 - 0.046 13.6 18.2 0.049 13.5 10.1 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2968 PF11180.3 EDO07666.1 - 0.081 12.2 7.8 0.13 11.6 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) FlaC_arch PF05377.6 EDO07666.1 - 0.11 12.4 11.6 0.16 11.9 1.9 3.5 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) THOC7 PF05615.8 EDO07666.1 - 0.16 12.2 14.7 0.94 9.7 10.1 2.1 1 1 0 1 1 1 0 Tho complex subunit 7 AAA_23 PF13476.1 EDO07666.1 - 0.19 12.0 15.9 0.38 11.0 11.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.3 EDO07666.1 - 0.2 10.9 15.9 0.38 9.9 3.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BRE1 PF08647.6 EDO07666.1 - 0.2 11.6 14.3 1.4 8.9 5.3 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.7 EDO07666.1 - 0.28 10.9 9.5 0.87 9.3 6.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 EDO07666.1 - 0.28 10.7 12.4 0.67 9.5 8.4 1.7 1 1 1 2 2 2 0 IncA protein Atg14 PF10186.4 EDO07666.1 - 0.29 10.0 12.4 0.43 9.4 8.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MscS_porin PF12795.2 EDO07666.1 - 0.29 10.4 15.9 0.14 11.4 9.4 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF2730 PF10805.3 EDO07666.1 - 0.46 10.2 4.6 1.3 8.8 3.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) HR1 PF02185.11 EDO07666.1 - 0.53 10.0 14.7 0.35 10.6 1.8 2.7 1 1 1 2 2 2 0 Hr1 repeat V_ATPase_I PF01496.14 EDO07666.1 - 0.8 7.4 9.4 1.1 6.9 6.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF603 PF04645.7 EDO07666.1 - 0.9 9.4 16.4 9.3 6.1 10.2 2.6 2 1 0 2 2 1 0 Protein of unknown function, DUF603 DUF4140 PF13600.1 EDO07666.1 - 2 8.8 8.8 2.6 8.5 2.9 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.1 EDO07666.1 - 2.6 6.9 10.4 4.7 6.0 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.3 EDO07666.1 - 7 6.5 18.2 2.4 8.0 4.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EDO07667.1 - 0.00011 22.0 3.4 0.00021 21.1 0.8 2.2 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) EzrA PF06160.7 EDO07667.1 - 0.0048 15.1 0.8 0.0048 15.1 0.6 1.4 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA Tropomyosin_1 PF12718.2 EDO07667.1 - 0.0054 16.5 1.8 0.0054 16.5 1.2 1.8 2 0 0 2 2 2 1 Tropomyosin like CENP-F_leu_zip PF10473.4 EDO07667.1 - 0.0062 16.3 1.1 0.0062 16.3 0.8 1.5 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 EDO07667.1 - 0.0072 16.0 4.2 0.44 10.2 1.4 2.2 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF2353 PF09789.4 EDO07667.1 - 0.012 14.9 1.1 0.012 14.9 0.8 1.6 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) HOOK PF05622.7 EDO07667.1 - 0.02 12.7 2.1 0.021 12.6 0.6 1.5 2 0 0 2 2 2 0 HOOK protein Ino80_Iec3 PF14612.1 EDO07667.1 - 0.028 14.4 0.6 0.057 13.4 0.2 1.6 1 1 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Sec34 PF04136.10 EDO07667.1 - 0.029 14.0 0.8 0.052 13.2 0.6 1.4 1 0 0 1 1 1 0 Sec34-like family APG6 PF04111.7 EDO07667.1 - 0.037 13.0 2.3 0.067 12.2 1.6 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 EDO07667.1 - 0.043 12.4 2.0 0.086 11.4 0.2 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Scaffolding_pro PF11418.3 EDO07667.1 - 0.055 13.7 2.0 0.21 11.9 0.3 2.2 2 0 0 2 2 2 0 Phi29 scaffolding protein Katanin_con80 PF13925.1 EDO07667.1 - 0.056 13.1 0.4 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 con80 domain of Katanin DivIC PF04977.10 EDO07667.1 - 0.069 12.6 6.4 0.093 12.2 0.9 2.9 2 1 1 3 3 3 0 Septum formation initiator Mt_ATP-synt_D PF05873.7 EDO07667.1 - 0.076 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) TMF_DNA_bd PF12329.3 EDO07667.1 - 0.085 12.6 7.3 1.3 8.9 0.4 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding HAUS-augmin3 PF14932.1 EDO07667.1 - 0.11 11.6 3.8 0.051 12.7 1.2 1.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 IncA PF04156.9 EDO07667.1 - 0.14 11.6 6.8 0.039 13.5 2.3 1.7 2 0 0 2 2 2 0 IncA protein V_ATPase_I PF01496.14 EDO07667.1 - 0.16 9.8 0.4 0.17 9.7 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.3 EDO07667.1 - 0.19 11.6 7.1 0.16 11.8 2.9 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1192 PF06698.6 EDO07667.1 - 0.19 11.5 9.1 0.15 11.8 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF972 PF06156.8 EDO07667.1 - 0.23 11.7 1.8 0.34 11.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) GAS PF13851.1 EDO07667.1 - 0.24 10.5 5.0 0.2 10.8 2.0 1.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-Q PF13094.1 EDO07667.1 - 0.48 10.4 7.7 1.2 9.1 3.2 2.4 2 1 0 2 2 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 EDO07667.1 - 0.7 8.7 6.3 0.41 9.5 3.2 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 EDO07667.1 - 0.8 10.0 7.2 2.8 8.2 2.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Striatin PF08232.7 EDO07667.1 - 0.82 9.9 4.1 6 7.1 1.0 2.4 1 1 1 2 2 2 0 Striatin family Adeno_PIX PF03955.9 EDO07667.1 - 1.3 9.5 3.7 2.1 8.9 0.7 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) TPR_MLP1_2 PF07926.7 EDO07667.1 - 2.7 7.7 7.1 1.2 8.8 1.7 2.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EDO07668.1 - 0.028 13.4 5.3 0.034 13.1 2.1 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Takusan PF04822.8 EDO07668.1 - 2.2 8.0 12.3 1.1 9.0 5.5 2.6 3 0 0 3 3 3 0 Takusan RRM_6 PF14259.1 EDO07669.1 - 5.6e-07 29.4 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO07669.1 - 0.00049 19.6 0.0 0.0012 18.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-Tim10_DDP PF02953.10 EDO07670.1 - 3.9e-14 51.6 0.6 4.7e-14 51.4 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger MPC PF03650.8 EDO07671.1 - 1.4e-29 102.4 0.1 1.7e-29 102.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) WD40 PF00400.27 EDO07672.1 - 2.3e-41 138.2 35.6 1.4e-10 40.6 0.5 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EDO07672.1 - 3.1e-05 23.3 0.3 0.086 12.3 0.1 3.0 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 EDO07672.1 - 0.023 13.4 5.6 0.058 12.1 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like zf-C2H2 PF00096.21 EDO07673.1 - 1.1e-20 72.6 31.3 1.8e-05 24.7 0.3 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO07673.1 - 1.1e-12 47.2 27.2 0.00093 19.3 1.5 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDO07673.1 - 5.7e-07 29.5 10.1 0.77 9.9 0.2 4.8 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDO07673.1 - 9.2e-06 25.6 7.5 0.0056 16.8 0.2 4.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EDO07673.1 - 0.00021 21.4 27.9 0.0071 16.5 0.4 6.3 7 0 0 7 7 7 3 Zinc-finger double domain zf-trcl PF13451.1 EDO07673.1 - 0.0095 15.5 0.9 0.024 14.2 0.6 1.6 1 0 0 1 1 1 1 Probable zinc-binding domain C1_4 PF07975.7 EDO07673.1 - 5 7.2 16.2 3.4 7.7 4.6 3.2 2 1 2 4 4 4 0 TFIIH C1-like domain zf-C2H2_6 PF13912.1 EDO07673.1 - 5.8 6.9 19.2 8.2 6.4 0.0 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger zf-LYAR PF08790.6 EDO07673.1 - 7.7 6.3 9.8 13 5.5 0.5 4.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger LSM PF01423.17 EDO07674.1 - 2.1e-15 56.0 0.1 2.6e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain Mago-bind PF09282.5 EDO07675.1 - 1.8e-12 46.6 4.6 2.7e-12 45.9 3.2 1.3 1 0 0 1 1 1 1 Mago binding eIF-5_eIF-2B PF01873.12 EDO07676.1 - 1.5e-36 124.7 0.1 3e-36 123.8 0.1 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EDO07676.1 - 3.8e-07 29.9 3.0 4.9e-07 29.6 0.0 2.6 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon U79_P34 PF03064.11 EDO07676.1 - 0.14 11.6 9.9 0.22 11.0 6.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2201_N PF13203.1 EDO07676.1 - 0.29 10.2 2.4 0.41 9.7 1.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain RNA_pol_Rpc4 PF05132.9 EDO07676.1 - 0.41 10.6 5.8 0.84 9.6 4.0 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Med19 PF10278.4 EDO07676.1 - 2.1 7.9 14.7 4.3 6.9 10.2 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Protocadherin PF08374.6 EDO07676.1 - 6.5 6.3 8.3 9.8 5.7 5.8 1.2 1 0 0 1 1 1 0 Protocadherin Ribosomal_L7Ae PF01248.21 EDO07677.1 - 1.4e-18 66.1 0.4 2e-18 65.6 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATPgrasp_Ter PF15632.1 EDO07677.1 - 0.06 12.0 0.0 0.084 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon X8 PF07983.8 EDO07677.1 - 0.13 12.7 0.1 0.21 12.1 0.1 1.4 1 0 0 1 1 1 0 X8 domain Ribosomal_S19e PF01090.14 EDO07678.1 - 6.1e-44 148.8 0.0 7.1e-44 148.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e GDI PF00996.13 EDO07679.1 - 9.8e-190 630.4 0.1 1.1e-189 630.2 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Ribosomal_S17e PF00833.13 EDO07681.1 - 9.8e-33 112.5 0.0 1.2e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cytochrom_B_N_2 PF13631.1 EDO07681.1 - 0.0088 15.8 0.9 0.011 15.5 0.5 1.3 1 1 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Phlebovirus_G1 PF07243.6 EDO07681.1 - 0.063 11.4 0.5 0.073 11.2 0.3 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 VESA1_N PF12785.2 EDO07682.1 - 3.1e-13 49.4 0.0 3.1e-13 49.4 0.0 2.5 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO07683.1 - 1.2e-95 321.2 2.9 1.6e-95 320.7 2.0 1.2 1 0 0 1 1 1 1 Variant erythrocyte surface antigen-1 TFIIE_beta PF02186.10 EDO07683.1 - 0.055 13.4 0.3 0.47 10.4 0.1 2.5 2 1 0 3 3 3 0 TFIIE beta subunit core domain Ribosomal_L12 PF00542.14 EDO07683.1 - 2.4 8.2 16.9 0.19 11.7 2.0 3.1 3 1 1 4 4 4 0 Ribosomal protein L7/L12 C-terminal domain Ribosomal_S17e PF00833.13 EDO07684.1 - 9.8e-33 112.5 0.0 1.2e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cytochrom_B_N_2 PF13631.1 EDO07684.1 - 0.0088 15.8 0.9 0.011 15.5 0.5 1.3 1 1 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Phlebovirus_G1 PF07243.6 EDO07684.1 - 0.063 11.4 0.5 0.073 11.2 0.3 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 PIRT PF15099.1 EDO07686.1 - 1.4 8.1 14.0 7.3 5.8 0.0 4.3 4 0 0 4 4 4 0 Phosphoinositide-interacting protein family ComX PF05952.7 EDO07688.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacillus competence pheromone ComX Chitin_synth_2 PF03142.10 EDO07688.1 - 1.9 6.7 8.2 2 6.7 4.8 1.6 1 1 0 1 1 1 0 Chitin synthase VESA1_N PF12785.2 EDO07689.1 - 2e-170 567.7 57.4 6.9e-162 539.6 16.9 2.6 2 1 0 2 2 2 2 Variant erythrocyte surface antigen-1 Laminin_II PF06009.7 EDO07689.1 - 0.053 13.2 1.6 0.12 12.0 0.4 2.0 2 0 0 2 2 2 0 Laminin Domain II Pox_A6 PF04924.7 EDO07689.1 - 0.38 9.5 0.0 0.63 8.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A6 protein Cytochrom_B562 PF07361.6 EDO07689.1 - 1.1 9.7 3.9 0.79 10.1 1.1 1.9 2 0 0 2 2 2 0 Cytochrome b562 DUF3493 PF11998.3 EDO07690.1 - 0.014 15.3 0.2 0.014 15.3 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) Lon_2 PF13337.1 EDO07691.1 - 0.0089 14.4 0.0 0.037 12.3 0.0 1.8 1 1 1 2 2 2 1 Putative ATP-dependent Lon protease ING PF12998.2 EDO07691.1 - 0.064 13.5 0.3 2.2 8.6 0.1 2.6 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4414 PF14377.1 EDO07691.1 - 0.082 12.8 0.4 24 4.9 0.2 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4414) Ribosomal_S17e PF00833.13 EDO07692.1 - 8.4e-61 203.1 1.2 9.6e-61 202.9 0.9 1.0 1 0 0 1 1 1 1 Ribosomal S17 Met_10 PF02475.11 EDO07693.1 - 5.8e-62 208.8 0.3 7.4e-62 208.5 0.2 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.5 EDO07693.1 - 0.0025 17.3 0.1 0.0062 16.1 0.0 1.6 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EDO07693.1 - 0.0025 17.8 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO07693.1 - 0.011 16.3 0.1 0.025 15.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 EDO07693.1 - 0.014 14.5 0.1 0.65 9.0 0.0 2.5 2 1 1 3 3 3 0 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.11 EDO07693.1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_23 PF13489.1 EDO07693.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EDO07693.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 VESA1_N PF12785.2 EDO07694.1 - 1.1e-19 70.8 1.3 1.1e-19 70.8 0.9 3.0 3 1 0 3 3 3 1 Variant erythrocyte surface antigen-1 Peptidase_S49 PF01343.13 EDO07694.1 - 0.12 12.1 0.1 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 VESA1_N PF12785.2 EDO07695.1 - 2.7e-183 610.1 19.6 2.7e-183 610.1 13.6 3.4 3 1 0 3 3 3 1 Variant erythrocyte surface antigen-1 DisA-linker PF10635.4 EDO07695.1 - 0.51 9.8 1.6 0.58 9.6 0.0 1.9 2 0 0 2 2 2 0 DisA bacterial checkpoint controller linker region MCPVI PF02993.9 EDO07695.1 - 0.7 9.9 3.5 18 5.3 0.7 2.3 2 0 0 2 2 2 0 Minor capsid protein VI Claudin_2 PF13903.1 EDO07696.1 - 0.84 9.3 26.1 0.035 13.7 2.1 4.1 1 1 2 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction ODV-E18 PF10717.4 EDO07696.1 - 1.5 8.2 5.4 10 5.6 0.0 3.0 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 VESA1_N PF12785.2 EDO07697.1 - 3.7e-155 517.4 14.6 3.7e-155 517.4 10.1 1.4 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 BTP PF05232.7 EDO07698.1 - 0.019 14.6 2.3 0.019 14.6 1.6 3.3 4 0 0 4 4 4 0 Bacterial Transmembrane Pair family DUF2561 PF10812.3 EDO07698.1 - 8.7 5.8 11.4 0.37 10.3 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2561) DUF3094 PF11293.3 EDO07698.1 - 9.3 5.8 9.0 0.68 9.4 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) DUF3493 PF11998.3 EDO07700.1 - 3.2 7.7 7.0 0.15 11.9 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) PMP1_2 PF08114.6 EDO07700.1 - 6 6.4 9.1 3.4 7.2 0.0 3.6 3 0 0 3 3 3 0 ATPase proteolipid family ING PF12998.2 EDO07701.1 - 0.0055 16.9 0.8 0.1 12.8 0.2 2.7 1 1 2 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding WAC_Acf1_DNA_bd PF10537.4 EDO07701.1 - 0.008 16.3 0.4 8.7 6.5 0.0 3.4 1 1 2 4 4 4 2 ATP-utilising chromatin assembly and remodelling N-terminal Lon_2 PF13337.1 EDO07701.1 - 0.068 11.5 0.0 0.12 10.6 0.0 1.5 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease FliG_M PF14841.1 EDO07701.1 - 0.098 12.6 0.1 5.7 7.0 0.0 3.0 3 0 0 3 3 3 0 FliG middle domain Ribosomal_S17e PF00833.13 EDO07702.1 - 8.4e-61 203.1 1.2 9.6e-61 202.9 0.9 1.0 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_L28e PF01778.12 EDO07704.1 - 1.2e-25 90.1 0.2 1.2e-25 90.1 0.1 1.8 1 1 1 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EDO07704.1 - 1.1e-13 51.1 13.0 2.7e-13 49.8 9.0 1.6 1 0 0 1 1 1 1 Mak16 protein C-terminal region RHH_3 PF12651.2 EDO07704.1 - 0.019 14.6 1.0 0.27 10.9 0.1 2.9 3 1 0 3 3 3 0 Ribbon-helix-helix domain D123 PF07065.9 EDO07704.1 - 0.049 12.7 2.8 0.033 13.2 0.6 1.6 1 1 1 2 2 2 0 D123 DUF2250 PF10007.4 EDO07704.1 - 0.79 9.6 6.4 0.91 9.4 2.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) DUF3523 PF12037.3 EDO07705.1 - 4.4e-85 285.0 41.7 4.4e-85 285.0 28.9 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3523) AAA PF00004.24 EDO07705.1 - 1.6e-25 89.8 0.0 3.5e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDO07705.1 - 4.4e-05 22.6 0.0 4.4e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EDO07705.1 - 6.5e-05 23.0 4.4 0.0038 17.2 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EDO07705.1 - 8.1e-05 22.7 5.6 0.011 15.8 0.0 3.2 2 1 0 3 3 3 2 AAA domain AAA_14 PF13173.1 EDO07705.1 - 0.00021 21.1 0.0 0.00076 19.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zot PF05707.7 EDO07705.1 - 0.00067 19.1 0.0 0.018 14.4 0.0 2.7 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_25 PF13481.1 EDO07705.1 - 0.00079 18.8 3.7 0.15 11.4 0.1 2.8 2 1 1 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EDO07705.1 - 0.0011 18.1 0.6 0.0049 16.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EDO07705.1 - 0.0012 18.4 0.0 0.0045 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EDO07705.1 - 0.0013 18.2 0.0 0.0038 16.6 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EDO07705.1 - 0.0017 18.0 0.1 0.013 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 EDO07705.1 - 0.0032 17.5 0.0 0.01 15.8 0.0 1.9 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_17 PF13207.1 EDO07705.1 - 0.0041 17.9 3.5 0.0082 16.9 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EDO07705.1 - 0.015 15.0 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 EDO07705.1 - 0.017 15.2 0.0 0.049 13.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EDO07705.1 - 0.024 14.5 0.1 0.024 14.5 0.0 2.8 2 2 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EDO07705.1 - 0.19 12.0 0.1 0.19 12.0 0.1 3.3 3 2 0 3 3 2 0 AAA domain AAA_11 PF13086.1 EDO07705.1 - 1.5 8.3 0.0 1.5 8.3 0.0 3.3 2 1 0 2 2 1 0 AAA domain Ins_P5_2-kin PF06090.7 EDO07706.1 - 1.5e-14 53.8 0.0 1.8e-13 50.2 0.0 2.1 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Pkinase PF00069.20 EDO07707.1 - 1e-55 188.6 0.0 1.5e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO07707.1 - 2.5e-25 89.0 0.0 2e-24 86.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO07707.1 - 0.003 16.5 0.0 0.37 9.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EDO07707.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SRP40_C PF05022.7 EDO07708.1 - 1.7e-26 92.4 3.4 2.8e-26 91.8 2.4 1.3 1 0 0 1 1 1 1 SRP40, C-terminal domain TAF PF02969.12 EDO07709.1 - 8.8e-08 31.9 0.0 1.5e-06 28.0 0.0 3.1 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 EDO07709.1 - 2.1e-06 27.7 0.0 8.9e-06 25.7 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) DUF4111 PF13427.1 EDO07709.1 - 0.021 14.6 0.2 0.38 10.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4111) PMBR PF09373.5 EDO07710.1 - 0.062 13.2 0.0 0.46 10.5 0.0 2.6 3 0 0 3 3 3 0 Pseudomurein-binding repeat Ham1p_like PF01725.11 EDO07712.1 - 5.2e-55 185.7 0.0 5.9e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Rdx PF10262.4 EDO07712.1 - 0.081 12.9 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 Rdx family PX PF00787.19 EDO07713.1 - 0.00092 18.9 0.7 0.0029 17.3 0.2 2.0 2 0 0 2 2 2 1 PX domain Syntaxin-6_N PF09177.6 EDO07713.1 - 0.056 13.8 8.0 0.052 13.9 1.1 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Sipho_Gp157 PF05565.6 EDO07713.1 - 0.85 9.1 5.6 0.1 12.1 0.6 1.8 2 0 0 2 2 2 0 Siphovirus Gp157 DUF2356 PF10189.4 EDO07714.1 - 0.0012 17.9 0.2 0.0027 16.7 0.1 1.5 1 0 0 1 1 1 1 Conserved protein (DUF2356) Ribosomal_S3Ae PF01015.13 EDO07715.1 - 5.8e-78 260.7 2.7 7e-78 260.4 1.9 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family TMA7 PF09072.5 EDO07716.1 - 2.2e-14 53.6 14.7 2.7e-14 53.3 10.2 1.2 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF2458 PF10454.4 EDO07716.1 - 0.055 13.3 1.5 0.055 13.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF2335 PF10097.4 EDO07716.1 - 0.96 9.1 4.3 1.3 8.6 3.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) GTP_EFTU PF00009.22 EDO07717.1 - 2.4e-60 203.2 0.0 3.3e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDO07717.1 - 3e-22 78.6 0.0 5.2e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDO07717.1 - 1.9e-15 56.7 2.5 1.9e-15 56.7 1.7 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO07717.1 - 1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDO07717.1 - 0.0054 17.2 0.1 0.052 14.0 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 EDO07717.1 - 0.0088 15.5 0.2 0.084 12.3 0.0 2.3 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU_D4 PF14578.1 EDO07717.1 - 0.011 15.3 1.1 0.029 13.9 0.7 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 EDO07717.1 - 0.14 11.6 4.8 0.37 10.2 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Polyoma_lg_T_C PF06431.6 EDO07717.1 - 0.15 10.7 0.0 4.7 5.7 0.0 2.1 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus Topoisom_bac PF01131.15 EDO07718.1 - 4.7e-98 328.6 0.0 5.7e-98 328.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EDO07718.1 - 3.7e-17 62.1 0.0 1.6e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 Toprim domain RRM_1 PF00076.17 EDO07719.1 - 1.1e-36 124.2 0.4 8.3e-15 54.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07719.1 - 6.2e-34 115.6 1.3 1e-12 47.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07719.1 - 1.7e-29 101.5 0.4 2.3e-12 46.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EDO07719.1 - 0.0077 16.4 0.2 0.024 14.9 0.0 1.8 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein ALS_ss_C PF10369.4 EDO07719.1 - 0.063 13.0 0.2 0.21 11.3 0.1 1.9 1 0 0 1 1 1 0 Small subunit of acetolactate synthase RRM_3 PF08777.6 EDO07719.1 - 0.34 10.7 0.0 0.34 10.7 0.0 3.2 4 0 0 4 4 4 0 RNA binding motif MFS_1 PF07690.11 EDO07720.1 - 0.16 10.6 7.7 0.073 11.7 3.4 1.8 2 0 0 2 2 2 0 Major Facilitator Superfamily Peptidase_U4 PF03419.8 EDO07720.1 - 0.91 8.5 13.6 0.04 12.9 5.5 1.6 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DUF3273 PF11677.3 EDO07721.1 - 8.7e-110 366.1 10.5 1e-109 365.8 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Vps52 PF04129.7 EDO07722.1 - 2.8e-39 135.0 3.4 7.4e-39 133.6 2.3 1.6 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EDO07722.1 - 0.0027 15.9 6.0 0.18 9.9 0.2 3.1 3 0 0 3 3 3 2 Exocyst complex component Sec3 DUF3829 PF12889.2 EDO07722.1 - 0.019 14.1 0.2 0.074 12.2 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Bacillus_HBL PF05791.6 EDO07722.1 - 0.92 8.8 6.4 5.5 6.3 0.1 3.3 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) V-ATPase_G PF03179.10 EDO07723.1 - 4.3e-18 65.5 8.1 5e-18 65.3 5.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit CHASE3 PF05227.8 EDO07723.1 - 0.01 15.5 1.9 0.013 15.1 1.0 1.5 1 1 0 1 1 1 0 CHASE3 domain DUF3584 PF12128.3 EDO07723.1 - 0.014 12.7 4.7 0.016 12.5 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATP-synt_B PF00430.13 EDO07723.1 - 0.026 14.3 10.6 0.066 13.0 6.6 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) MRP-S27 PF10037.4 EDO07723.1 - 0.039 12.8 4.3 0.051 12.5 3.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Thioredoxin_9 PF14595.1 EDO07723.1 - 0.098 12.2 0.2 0.16 11.5 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin Retrotrans_gag PF03732.12 EDO07723.1 - 0.099 12.7 0.8 0.2 11.7 0.6 1.6 1 1 0 1 1 1 0 Retrotransposon gag protein YlqD PF11068.3 EDO07723.1 - 0.15 12.1 4.2 0.13 12.2 2.4 1.3 1 1 0 1 1 1 0 YlqD protein Hemerythrin PF01814.18 EDO07723.1 - 0.19 11.9 5.1 0.28 11.3 3.6 1.2 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain SelB-wing_2 PF09106.6 EDO07723.1 - 0.26 11.2 2.6 7.2 6.6 0.2 2.7 3 0 0 3 3 3 0 Elongation factor SelB, winged helix DUF2962 PF11176.3 EDO07723.1 - 0.36 10.4 4.2 0.45 10.0 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) Myb_DNA-binding PF00249.26 EDO07723.1 - 0.4 10.7 1.8 1.8 8.7 1.3 2.1 1 1 0 1 1 1 0 Myb-like DNA-binding domain Exonuc_VII_L PF02601.10 EDO07723.1 - 0.91 8.6 3.9 1.1 8.4 2.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Acetyltransf_1 PF00583.19 EDO07724.1 - 2.2e-17 62.8 0.0 4.7e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO07724.1 - 1.1e-09 38.2 0.0 2.8e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO07724.1 - 2.3e-05 24.4 0.1 7.5e-05 22.8 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EDO07724.1 - 2.4e-05 24.3 0.0 5.7e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EDO07724.1 - 0.0026 17.6 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EDO07724.1 - 0.0031 17.2 0.0 0.0082 15.8 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein DUF3749 PF12568.3 EDO07724.1 - 0.038 13.5 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L23 PF00276.15 EDO07725.1 - 5.3e-19 67.9 1.0 5.3e-19 67.9 0.7 2.3 2 2 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 EDO07725.1 - 6.7e-06 26.0 5.8 6.7e-06 26.0 4.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain SRPRB PF09439.5 EDO07725.1 - 0.0037 16.5 0.4 0.0051 16.0 0.2 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ribosomal_L4 PF00573.17 EDO07725.1 - 0.6 9.4 3.5 0.73 9.1 2.4 1.3 1 1 0 1 1 1 0 Ribosomal protein L4/L1 family Paf1 PF03985.8 EDO07726.1 - 2.6e-05 23.1 0.0 0.00013 20.8 0.0 2.1 2 1 0 2 2 2 1 Paf1 Tox-REase-2 PF15646.1 EDO07726.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 Got1 PF04178.7 EDO07728.1 - 2.5e-22 79.2 18.5 3.2e-22 78.8 12.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1218 PF06749.7 EDO07728.1 - 0.83 10.1 7.3 0.88 10.0 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) RCC1 PF00415.13 EDO07730.1 - 1.9e-32 111.2 6.5 3.3e-13 49.6 0.0 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDO07730.1 - 9.7e-24 82.4 13.8 3.2e-06 26.6 0.0 6.5 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RE_TaqI PF09573.5 EDO07730.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 TaqI restriction endonuclease Asp PF00026.18 EDO07731.1 - 1.3e-13 50.8 1.8 1.5e-10 40.7 0.1 2.9 2 2 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDO07731.1 - 5.1e-12 46.0 0.7 8e-12 45.4 0.1 1.6 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EDO07731.1 - 0.011 15.5 0.0 7.7 6.4 0.0 2.8 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDO07731.1 - 0.03 14.8 0.1 19 5.8 0.0 3.7 4 0 0 4 4 4 0 Aspartyl protease UCH PF00443.24 EDO07732.1 - 6e-29 100.9 0.0 1.1e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO07732.1 - 8.8e-08 31.9 0.0 1.2e-06 28.2 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase LYTB PF02401.13 EDO07733.1 - 7.4e-93 310.5 0.1 9.5e-93 310.1 0.1 1.1 1 0 0 1 1 1 1 LytB protein DUF3228 PF11539.3 EDO07734.1 - 4.8e-84 280.3 0.0 5.4e-84 280.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) Pyr_redox_2 PF07992.9 EDO07735.1 - 4.1e-24 85.5 0.0 1.2e-23 84.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EDO07735.1 - 3e-14 52.3 0.5 6.9e-14 51.1 0.3 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 EDO07735.1 - 5.9e-14 52.2 3.1 2.8e-12 46.8 0.8 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDO07735.1 - 8.1e-10 38.1 0.2 0.0002 20.4 0.1 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase Rieske_2 PF13806.1 EDO07735.1 - 4.7e-08 32.6 0.1 6.2e-07 29.0 0.0 2.6 3 0 0 3 3 2 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.1 EDO07735.1 - 4.9e-07 30.0 0.2 3.2e-05 24.1 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EDO07735.1 - 2.7e-05 24.3 0.0 0.00013 22.1 0.0 2.2 2 0 0 2 2 2 1 Reductase C-terminal TrkA_N PF02254.13 EDO07735.1 - 0.021 14.8 0.4 9.4 6.2 0.0 3.7 3 1 1 4 4 4 0 TrkA-N domain NAD_binding_7 PF13241.1 EDO07735.1 - 0.023 14.9 0.8 0.46 10.7 0.2 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EDO07735.1 - 0.027 14.2 0.0 0.027 14.2 0.0 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF1188 PF06690.6 EDO07735.1 - 0.031 13.4 0.9 0.46 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) 3HCDH_N PF02737.13 EDO07735.1 - 0.034 13.7 1.7 0.062 12.9 1.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EDO07735.1 - 0.048 13.6 0.6 35 4.5 0.3 3.6 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain SH3_5 PF08460.5 EDO07735.1 - 0.11 12.4 0.1 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain Amino_oxidase PF01593.19 EDO07735.1 - 0.3 10.1 0.7 0.54 9.2 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EDO07735.1 - 0.42 9.4 6.4 5.7 5.7 0.0 3.6 3 1 1 4 4 4 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EDO07735.1 - 5.5 5.4 8.5 1.1 7.8 0.2 3.0 2 1 1 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.9 EDO07735.1 - 7.7 4.8 8.4 2.1 6.7 0.0 3.3 3 1 1 4 4 4 0 HI0933-like protein Chorein_N PF12624.2 EDO07737.1 - 5.5e-30 103.3 0.1 1.3e-29 102.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EDO07737.1 - 0.035 14.2 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 ATG C terminal domain DEAD PF00270.24 EDO07738.1 - 7.3e-15 54.8 0.0 1.4e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDO07738.1 - 5e-07 29.7 0.0 8.5e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDO07738.1 - 0.0011 18.7 0.0 0.0028 17.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ras PF00071.17 EDO07739.1 - 4.2e-57 192.0 0.7 5.1e-57 191.7 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO07739.1 - 2e-19 70.2 0.1 4.6e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EDO07739.1 - 1.5e-12 47.0 0.0 1.9e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDO07739.1 - 5.4e-07 29.5 0.0 9.2e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EDO07739.1 - 7.4e-07 28.5 0.1 8.9e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO07739.1 - 2.4e-05 23.8 0.2 0.00056 19.4 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 EDO07739.1 - 0.00012 21.8 0.1 0.00019 21.2 0.1 1.6 1 1 0 1 1 1 1 Archaeal ATPase DUF258 PF03193.11 EDO07739.1 - 0.00025 20.2 0.0 0.0011 18.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Septin PF00735.13 EDO07739.1 - 0.00071 18.6 0.1 0.0032 16.5 0.0 1.9 2 0 0 2 2 2 1 Septin MobB PF03205.9 EDO07739.1 - 0.00075 19.2 0.0 0.0017 18.0 0.0 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EDO07739.1 - 0.0014 18.7 0.0 0.0035 17.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.5 EDO07739.1 - 0.0016 17.7 0.1 0.0028 16.9 0.0 1.4 2 0 0 2 2 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EDO07739.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EDO07739.1 - 0.0029 17.0 0.1 0.0078 15.6 0.0 1.7 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EDO07739.1 - 0.0043 16.6 0.2 0.51 9.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EDO07739.1 - 0.0051 16.8 0.0 0.013 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 EDO07739.1 - 0.013 15.0 0.1 0.026 13.9 0.0 1.3 1 1 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 EDO07739.1 - 0.017 14.6 0.1 0.035 13.5 0.1 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EDO07739.1 - 0.02 14.5 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 EDO07739.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.1 EDO07739.1 - 0.036 13.9 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDO07739.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EDO07739.1 - 0.05 13.8 0.4 0.082 13.2 0.3 1.7 1 1 0 1 1 1 0 ABC transporter TrwB_AAD_bind PF10412.4 EDO07739.1 - 0.062 11.9 0.0 0.13 10.8 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATP-synt_ab PF00006.20 EDO07739.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.15 EDO07739.1 - 0.081 11.6 1.3 0.28 9.8 0.1 2.1 2 1 0 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.13 EDO07739.1 - 0.084 12.1 0.3 0.4 9.9 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF2305 PF10230.4 EDO07740.1 - 0.15 11.4 0.3 0.17 11.2 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Rer1 PF03248.8 EDO07741.1 - 1.1e-61 207.5 8.5 1.3e-61 207.3 5.9 1.0 1 0 0 1 1 1 1 Rer1 family EmrE PF13536.1 EDO07741.1 - 1.4 9.1 9.9 0.87 9.8 2.2 2.3 2 0 0 2 2 2 0 Multidrug resistance efflux transporter Cullin PF00888.17 EDO07743.1 - 1.9e-44 152.2 8.8 3e-44 151.5 6.1 1.2 1 0 0 1 1 1 1 Cullin family DOT1 PF08123.8 EDO07744.1 - 2e-05 24.0 0.0 4.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 Apc4 PF12896.2 EDO07744.1 - 0.087 12.1 0.1 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 zf-RanBP PF00641.13 EDO07745.1 - 0.00023 20.2 1.9 0.00038 19.4 1.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Img2 PF05046.9 EDO07746.1 - 4.4e-11 42.8 0.7 4.4e-11 42.8 0.5 1.5 2 1 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) DinI PF06183.8 EDO07746.1 - 0.037 14.0 0.0 1.1 9.3 0.0 2.2 1 1 0 1 1 1 0 DinI-like family AAA_12 PF13087.1 EDO07748.1 - 3.6e-54 183.2 0.0 1.3e-53 181.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EDO07748.1 - 1.5e-42 145.7 0.0 9.2e-42 143.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO07748.1 - 1.1e-13 50.6 0.1 4.1e-13 48.8 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EDO07748.1 - 6.3e-09 35.6 0.0 1.7e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain dsrm PF00035.20 EDO07748.1 - 6.6e-06 26.6 0.3 0.024 15.2 0.0 3.8 4 1 0 4 4 3 1 Double-stranded RNA binding motif PIF1 PF05970.9 EDO07748.1 - 0.00038 19.5 0.0 0.012 14.5 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.4 EDO07748.1 - 0.00067 18.7 0.0 0.17 10.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EDO07748.1 - 0.00092 18.4 0.0 0.0095 15.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.10 EDO07748.1 - 0.0022 17.8 0.0 0.01 15.6 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EDO07748.1 - 0.005 16.5 0.0 0.016 14.8 0.0 1.9 1 1 0 1 1 1 1 Helicase T2SE PF00437.15 EDO07748.1 - 0.0075 15.2 0.0 0.019 13.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.24 EDO07748.1 - 0.0083 15.6 0.0 0.02 14.3 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 EDO07748.1 - 0.012 15.0 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EDO07748.1 - 0.013 14.7 0.0 0.071 12.2 0.0 2.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EDO07748.1 - 0.013 15.6 0.0 0.17 12.0 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDO07748.1 - 0.026 13.9 0.0 0.19 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EDO07748.1 - 0.028 14.7 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.9 EDO07748.1 - 0.032 13.9 0.3 0.21 11.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DNA_pol3_alpha PF07733.7 EDO07748.1 - 0.054 11.9 0.4 6.7 5.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial DNA polymerase III alpha subunit UvrD-helicase PF00580.16 EDO07748.1 - 0.078 12.2 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain NACHT PF05729.7 EDO07748.1 - 0.083 12.5 0.0 0.26 10.9 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Alba PF01918.16 EDO07749.1 - 1.6e-12 46.8 0.0 2.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Alba Steroid_dh PF02544.11 EDO07750.1 - 6.9e-31 107.0 13.3 1.1e-30 106.3 9.2 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase UAE_UbL PF14732.1 EDO07750.1 - 0.12 12.4 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain BRE1 PF08647.6 EDO07751.1 - 0.00033 20.5 21.1 0.00039 20.3 6.4 3.3 3 0 0 3 3 3 1 BRE1 E3 ubiquitin ligase CorA PF01544.13 EDO07751.1 - 0.0023 17.0 9.4 0.0023 17.0 6.5 2.5 1 1 2 3 3 3 2 CorA-like Mg2+ transporter protein NPV_P10 PF05531.7 EDO07751.1 - 0.0026 17.9 12.5 0.89 9.8 0.0 4.4 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 EDO07751.1 - 0.0039 17.0 8.7 0.0039 17.0 6.0 2.7 2 1 1 3 3 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 EDO07751.1 - 0.012 14.0 27.1 0.033 12.6 18.8 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Nup54 PF13874.1 EDO07751.1 - 0.015 14.9 19.3 0.019 14.6 6.3 2.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 USP8_interact PF08941.5 EDO07751.1 - 0.019 14.3 0.3 0.019 14.3 0.2 2.4 2 1 0 2 2 2 0 USP8 interacting Pox_A_type_inc PF04508.7 EDO07751.1 - 0.042 13.6 0.2 0.042 13.6 0.1 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Mnd1 PF03962.10 EDO07751.1 - 0.089 12.4 24.2 0.08 12.6 10.2 2.8 1 1 1 2 2 2 0 Mnd1 family ATG16 PF08614.6 EDO07751.1 - 0.11 12.3 30.3 1.4 8.7 7.0 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EDO07751.1 - 0.16 11.5 34.8 0.035 13.6 14.9 2.7 2 1 1 3 3 2 0 IncA protein Med9 PF07544.8 EDO07751.1 - 0.21 11.3 20.1 0.32 10.7 3.9 3.7 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2937 PF11157.3 EDO07751.1 - 0.99 8.7 4.3 1.4 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF972 PF06156.8 EDO07751.1 - 1.4 9.2 26.3 0.45 10.8 3.1 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 EDO07751.1 - 2 8.1 30.0 3.4 7.4 8.8 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 EDO07751.1 - 3.4 7.4 17.2 0.39 10.4 3.3 3.9 3 1 0 3 3 3 0 Homeobox associated leucine zipper Fib_alpha PF08702.5 EDO07751.1 - 5.4 7.1 21.7 12 6.0 9.4 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.6 EDO07751.1 - 6.2 7.2 22.8 3.5 8.0 4.4 3.7 2 2 1 3 3 3 0 Syntaxin 6, N-terminal APG6 PF04111.7 EDO07751.1 - 6.7 5.6 32.3 3.1 6.7 10.4 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF342 PF03961.8 EDO07751.1 - 7.7 4.8 26.1 3.8 5.8 5.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EDO07751.1 - 8.6 4.0 22.9 0.22 9.3 4.7 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF1515 PF07439.6 EDO07751.1 - 8.9 6.1 12.3 14 5.5 0.4 3.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) MOZART1 PF12554.3 EDO07752.1 - 8.8e-22 76.3 0.1 1.1e-21 75.9 0.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.2 EDO07752.1 - 0.063 12.8 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF1364 PF07102.7 EDO07752.1 - 0.08 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) DUF3893 PF13032.1 EDO07752.1 - 0.094 12.8 0.0 0.11 12.6 0.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3893) PH PF00169.24 EDO07753.1 - 0.17 12.1 6.5 4.5 7.5 0.0 3.9 3 2 0 3 3 3 0 PH domain Reo_sigmaC PF04582.7 EDO07753.1 - 0.31 10.1 10.7 0.22 10.6 5.1 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Tropomyosin PF00261.15 EDO07753.1 - 1.2 8.1 23.1 0.08 12.0 5.5 3.6 3 1 1 4 4 4 0 Tropomyosin ADIP PF11559.3 EDO07753.1 - 9.7 6.0 30.5 0.096 12.5 2.9 3.7 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding RRM_1 PF00076.17 EDO07754.1 - 1.9e-19 69.0 0.0 2.3e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07754.1 - 5.6e-16 58.2 0.0 6.5e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07754.1 - 7.5e-10 38.5 0.0 9.8e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDO07754.1 - 0.0002 21.1 0.0 0.00025 20.8 0.0 1.1 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 EDO07754.1 - 0.00027 20.6 0.0 0.00046 19.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EDO07754.1 - 0.036 13.8 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 CorC_HlyC PF03471.12 EDO07754.1 - 0.12 12.1 0.1 0.28 10.9 0.1 1.6 1 1 0 1 1 1 0 Transporter associated domain HHH_7 PF14635.1 EDO07755.1 - 3.9e-23 81.5 0.0 8.9e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 EDO07755.1 - 3.1e-09 36.8 0.1 9.4e-09 35.3 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2_2 PF14633.1 EDO07755.1 - 3.4e-09 36.0 0.0 7e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SPT6_acidic PF14632.1 EDO07755.1 - 8.4e-05 22.6 17.2 8.4e-05 22.6 11.9 4.0 3 1 0 3 3 3 1 Acidic N-terminal SPT6 MT-A70 PF05063.9 EDO07757.1 - 7.4e-53 178.6 0.3 1.2e-52 178.0 0.2 1.3 1 0 0 1 1 1 1 MT-A70 EF-hand_7 PF13499.1 EDO07758.1 - 3.3e-26 91.2 5.1 5.3e-15 55.3 1.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EDO07758.1 - 1.8e-24 83.1 5.6 1.3e-07 30.3 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EDO07758.1 - 1.3e-21 74.4 4.6 9.4e-08 31.3 0.0 4.7 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 EDO07758.1 - 6.6e-19 67.2 10.0 7.1e-09 35.1 0.6 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EDO07758.1 - 2.7e-16 58.0 7.0 4.6e-05 22.5 0.0 4.4 3 1 1 4 4 4 3 EF hand EF-hand_9 PF14658.1 EDO07758.1 - 8.6e-08 31.9 0.0 2e-05 24.4 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain Caleosin PF05042.8 EDO07758.1 - 0.0028 17.2 0.1 0.0063 16.0 0.0 1.8 1 1 0 1 1 1 1 Caleosin related protein DUF2764 PF10962.3 EDO07758.1 - 0.04 13.1 0.4 0.051 12.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) PMBR PF09373.5 EDO07758.1 - 0.067 13.1 0.6 11 6.1 0.0 3.7 3 1 1 4 4 4 0 Pseudomurein-binding repeat EF-hand_4 PF12763.2 EDO07758.1 - 0.15 11.8 1.6 13 5.5 0.1 2.8 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand CRISPR_Cse2 PF09485.5 EDO07761.1 - 0.028 14.4 0.0 0.04 13.9 0.0 1.3 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Ribosomal_L28e PF01778.12 EDO07762.1 - 1.7e-22 80.0 0.3 2e-22 79.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF3291 PF11695.3 EDO07762.1 - 0.035 13.5 0.0 0.074 12.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3291) Cyclin_N PF00134.18 EDO07763.1 - 7.1e-06 25.6 0.4 1.5e-05 24.5 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L35Ae PF01247.13 EDO07764.1 - 2.4e-42 142.6 0.9 2.8e-42 142.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EDO07764.1 - 0.0016 18.2 0.0 0.39 10.6 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Porin_3 PF01459.17 EDO07765.1 - 0.0016 17.7 1.1 0.002 17.4 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic porin cobW PF02492.14 EDO07766.1 - 3.8e-33 114.4 0.0 1.2e-32 112.8 0.0 1.9 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EDO07766.1 - 1.5e-05 24.6 0.0 5.3e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain ArgK PF03308.11 EDO07766.1 - 0.00023 20.0 0.0 0.16 10.6 0.0 2.3 2 0 0 2 2 2 2 ArgK protein AAA_33 PF13671.1 EDO07766.1 - 0.00083 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EDO07766.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EDO07766.1 - 0.0014 18.7 0.3 0.018 15.1 0.0 2.5 2 1 1 3 3 3 1 AAA domain MobB PF03205.9 EDO07766.1 - 0.0016 18.1 0.0 0.007 16.0 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EDO07766.1 - 0.012 15.9 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EDO07766.1 - 0.049 13.1 0.2 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 EDO07766.1 - 0.06 12.8 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EDO07766.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EDO07766.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain BOP1NT PF08145.7 EDO07767.1 - 9.9e-94 313.8 7.1 1.4e-93 313.4 4.9 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EDO07767.1 - 0.011 15.5 2.1 40 4.3 0.0 5.0 6 0 0 6 6 6 0 WD domain, G-beta repeat DUF1843 PF08898.5 EDO07768.1 - 2.8 8.0 14.1 5.9 7.0 0.0 6.3 5 1 2 7 7 7 0 Domain of unknown function (DUF1843) IKKbetaNEMObind PF12179.3 EDO07768.1 - 4.9 7.0 10.8 4.3 7.2 0.2 3.8 4 0 0 4 4 4 0 I-kappa-kinase-beta NEMO binding domain WD40 PF00400.27 EDO07770.1 - 5.8e-22 76.7 7.0 2.4e-08 33.5 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EDO07770.1 - 0.03 14.0 0.0 0.16 11.7 0.0 2.2 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Fcf1 PF04900.7 EDO07771.1 - 1.5e-24 86.0 0.3 3.7e-23 81.5 0.0 2.1 2 0 0 2 2 2 1 Fcf1 rRNA_processing PF08524.6 EDO07772.1 - 4.6e-07 29.7 7.2 4.6e-07 29.7 5.0 3.0 2 1 0 3 3 3 1 rRNA processing ABC_tran_2 PF12848.2 EDO07772.1 - 1.7 8.5 13.4 0.14 11.9 3.5 2.3 2 0 0 2 2 2 0 ABC transporter Vma12 PF11712.3 EDO07772.1 - 4.2 7.0 6.0 2.3 7.9 0.6 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase EMG1 PF03587.9 EDO07773.1 - 1.9e-30 105.6 0.3 3.8e-30 104.6 0.0 1.6 2 0 0 2 2 2 1 EMG1/NEP1 methyltransferase VanW PF04294.8 EDO07773.1 - 0.014 14.6 0.0 0.038 13.2 0.0 1.7 2 0 0 2 2 2 0 VanW like protein RFC1 PF08519.7 EDO07774.1 - 1.5e-36 125.4 0.0 2.8e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.24 EDO07774.1 - 2e-13 50.6 0.0 5.4e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 EDO07774.1 - 2.5e-10 40.3 0.0 6.9e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.10 EDO07774.1 - 5.6e-07 28.6 0.0 4.5e-06 25.6 0.0 2.6 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EDO07774.1 - 1.6e-05 25.7 0.3 4.9e-05 24.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EDO07774.1 - 3.1e-05 23.1 0.0 5.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 EDO07774.1 - 0.00041 19.9 0.0 0.00096 18.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EDO07774.1 - 0.00053 19.8 0.0 0.008 16.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain PTCB-BRCT PF12738.2 EDO07774.1 - 0.00056 19.7 0.0 0.0021 17.9 0.0 2.1 1 0 0 1 1 1 1 twin BRCT domain AAA_18 PF13238.1 EDO07774.1 - 0.00095 19.4 0.2 0.0034 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EDO07774.1 - 0.0017 17.5 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EDO07774.1 - 0.0024 17.8 0.0 0.0075 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EDO07774.1 - 0.0036 17.1 0.0 0.0097 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO07774.1 - 0.0038 17.3 0.1 0.014 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO07774.1 - 0.0047 16.6 0.1 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EDO07774.1 - 0.0088 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EDO07774.1 - 0.023 13.6 0.0 0.05 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 EDO07774.1 - 0.034 13.8 0.1 0.11 12.2 0.1 1.8 1 1 1 2 2 2 0 NTPase Sigma54_activ_2 PF14532.1 EDO07774.1 - 0.081 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4381 PF14316.1 EDO07775.1 - 0.47 10.5 2.9 0.25 11.4 0.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Ribosomal_S30 PF04758.9 EDO07776.1 - 4.4e-27 93.5 8.3 4.8e-27 93.4 5.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Sec1 PF00995.18 EDO07777.1 - 2.3e-110 369.8 0.2 2.6e-110 369.6 0.1 1.0 1 0 0 1 1 1 1 Sec1 family ATP-synt_ab PF00006.20 EDO07780.1 - 1.2e-70 237.4 0.0 1.6e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDO07780.1 - 5.7e-24 84.7 0.2 1.2e-23 83.7 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDO07780.1 - 3.5e-14 52.7 3.6 1.1e-13 51.2 2.5 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EDO07780.1 - 1.9e-07 30.8 2.4 3.9e-07 29.8 1.7 1.5 1 0 0 1 1 1 1 HAS barrel domain AAA_25 PF13481.1 EDO07780.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain CECR6_TMEM121 PF14997.1 EDO07781.1 - 2.8e-15 56.4 6.9 2.8e-15 56.4 4.8 2.9 2 2 1 3 3 3 1 CECR6/TMEM121 family SMK-1 PF04802.10 EDO07782.1 - 7.4e-24 84.3 0.5 1.5e-23 83.3 0.4 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Ran_BP1 PF00638.13 EDO07782.1 - 0.024 14.7 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 RanBP1 domain DNA_pol_E_B PF04042.11 EDO07783.1 - 1.1e-23 83.6 0.0 1.7e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B BING4CT PF08149.6 EDO07784.1 - 7.4e-28 95.8 1.4 1.1e-26 92.0 0.0 3.0 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.27 EDO07784.1 - 0.00014 21.6 0.0 0.0063 16.3 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat Cwf_Cwc_15 PF04889.7 EDO07785.1 - 7.7e-35 120.7 22.2 1e-32 113.7 15.4 2.0 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2721 PF11026.3 EDO07785.1 - 0.36 10.4 2.8 0.76 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) EF-1_beta_acid PF10587.4 EDO07785.1 - 1.8 8.8 9.7 17 5.7 6.7 2.8 1 1 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region YchF-GTPase_C PF06071.8 EDO07786.1 - 1.8e-39 133.4 0.1 4.7e-39 132.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EDO07786.1 - 6.9e-16 58.2 0.0 1.5e-15 57.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO07786.1 - 1.7e-05 24.1 0.0 3.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.24 EDO07786.1 - 0.0026 17.9 0.0 0.005 17.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDO07786.1 - 0.011 16.5 0.0 0.068 14.0 0.0 2.5 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 EDO07786.1 - 0.064 12.0 0.5 0.79 8.4 0.0 2.2 2 1 0 2 2 2 0 ArgK protein FHA PF00498.21 EDO07786.1 - 0.13 12.3 0.1 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 FHA domain NuA4 PF09340.5 EDO07787.1 - 0.00032 20.2 3.8 0.0036 16.9 0.1 3.4 2 2 0 2 2 2 1 Histone acetyltransferase subunit NuA4 BMFP PF04380.8 EDO07787.1 - 0.048 13.7 0.1 0.096 12.8 0.1 1.5 1 0 0 1 1 1 0 Membrane fusogenic activity zf-MYND PF01753.13 EDO07788.1 - 3.2e-06 26.9 6.4 3.2e-06 26.9 4.5 2.1 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 EDO07788.1 - 0.011 15.5 2.8 0.028 14.2 2.0 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 MRP-S25 PF13741.1 EDO07789.1 - 0.00018 21.0 0.0 0.00026 20.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 TPR_11 PF13414.1 EDO07790.1 - 4.6e-73 240.8 30.1 2.9e-19 68.4 0.4 6.3 5 1 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 EDO07790.1 - 2.8e-64 210.2 35.7 4.2e-09 35.6 0.2 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 EDO07790.1 - 1.4e-54 177.7 32.2 1.2e-07 31.0 0.1 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 EDO07790.1 - 1.2e-30 105.2 17.9 2.7e-09 36.8 0.9 6.2 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDO07790.1 - 2.2e-29 98.9 28.2 0.00015 21.3 0.9 9.4 9 1 1 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 EDO07790.1 - 3.6e-29 100.7 18.2 2.9e-05 24.6 0.2 6.7 4 3 3 7 7 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 EDO07790.1 - 6.5e-26 88.4 12.4 0.037 14.6 0.0 9.9 5 3 5 10 10 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 EDO07790.1 - 1.5e-25 87.1 14.1 3.8e-05 23.5 0.2 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EDO07790.1 - 4.4e-20 71.8 18.4 7.7e-07 29.3 0.4 6.8 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_9 PF13371.1 EDO07790.1 - 1.2e-17 63.4 8.2 3.6e-05 23.5 0.1 6.5 2 2 4 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 EDO07790.1 - 2.1e-13 48.9 20.8 0.002 17.7 0.2 8.8 9 1 0 9 9 9 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDO07790.1 - 2.2e-10 40.2 14.9 0.47 10.3 0.2 7.1 8 0 0 8 8 7 4 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 EDO07790.1 - 5.8e-09 35.9 19.1 0.00081 19.4 3.8 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDO07790.1 - 3.6e-07 30.1 24.1 0.86 10.1 0.2 8.5 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_10 PF13374.1 EDO07790.1 - 2e-06 27.5 14.7 0.52 10.3 0.0 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 EDO07790.1 - 4.8e-06 26.5 3.6 0.62 10.2 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.4 EDO07790.1 - 6.6e-06 26.1 11.3 0.05 13.5 0.5 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF3856 PF12968.2 EDO07790.1 - 0.00059 19.6 9.4 5 6.9 0.1 5.8 3 3 0 4 4 4 0 Domain of Unknown Function (DUF3856) NARP1 PF12569.3 EDO07790.1 - 0.0012 17.7 26.9 0.12 11.1 0.2 5.5 2 1 4 6 6 6 3 NMDA receptor-regulated protein 1 ChAPs PF09295.5 EDO07790.1 - 0.0036 16.1 2.2 0.71 8.5 0.0 3.6 3 1 1 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.12 EDO07790.1 - 0.0056 16.9 9.3 5.3 7.3 0.5 5.1 3 2 2 5 5 5 0 Bacterial transcriptional activator domain Rapsyn_N PF10579.4 EDO07790.1 - 0.015 15.0 0.6 0.098 12.4 0.1 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region MIT PF04212.13 EDO07790.1 - 0.018 14.9 18.9 0.21 11.5 1.3 6.0 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain XPC-binding PF09280.6 EDO07790.1 - 0.055 12.9 11.4 1.3 8.5 0.4 4.3 3 1 1 4 4 4 0 XPC-binding domain Alkyl_sulf_dimr PF14863.1 EDO07790.1 - 0.099 12.8 4.3 1.1 9.4 0.7 3.2 2 1 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_3 PF07720.7 EDO07790.1 - 0.12 12.2 15.3 2.2 8.1 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.15 EDO07790.1 - 0.12 12.4 4.6 16 5.7 0.1 4.7 4 0 0 4 4 3 0 PPR repeat Virulence_fact PF13769.1 EDO07790.1 - 0.24 11.2 5.7 0.25 11.2 0.6 3.2 3 1 0 3 3 2 0 Virulence factor TPR_4 PF07721.9 EDO07790.1 - 0.28 11.7 4.6 12 6.6 0.0 4.6 6 0 0 6 6 3 0 Tetratricopeptide repeat DUF3391 PF11871.3 EDO07790.1 - 0.3 11.2 4.7 3.6 7.8 1.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) vMSA PF00695.14 EDO07790.1 - 0.68 9.0 1.8 1.2 8.2 1.2 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus SHNi-TPR PF10516.4 EDO07790.1 - 2 7.6 13.0 34 3.7 0.1 6.5 7 0 0 7 7 7 0 SHNi-TPR DUF4137 PF13593.1 EDO07791.1 - 0.053 12.6 1.5 0.06 12.4 1.1 1.0 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) AAA_5 PF07728.9 EDO07792.1 - 6.3e-103 340.2 0.0 8.8e-20 70.8 0.0 8.7 7 1 1 8 8 8 8 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDO07792.1 - 5.5e-29 100.4 0.0 4.5e-10 39.2 0.0 6.3 7 0 0 7 7 6 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EDO07792.1 - 1.1e-15 58.0 0.1 0.026 14.7 0.0 5.8 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDO07792.1 - 3.9e-13 49.7 0.6 0.039 13.9 0.0 5.5 5 1 0 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 EDO07792.1 - 1.3e-12 48.0 0.0 0.13 12.4 0.0 5.3 4 0 0 4 4 4 3 AAA domain Sigma54_activ_2 PF14532.1 EDO07792.1 - 2.1e-12 47.2 0.0 0.049 13.6 0.0 5.8 5 0 0 5 5 5 3 Sigma-54 interaction domain AAA_18 PF13238.1 EDO07792.1 - 4.4e-12 46.4 0.1 0.021 15.1 0.0 5.2 5 0 0 5 5 4 2 AAA domain AAA_17 PF13207.1 EDO07792.1 - 7.7e-12 46.1 0.0 0.11 13.3 0.0 6.4 5 0 0 5 5 5 2 AAA domain Sigma54_activat PF00158.21 EDO07792.1 - 1.3e-09 37.7 0.0 0.081 12.4 0.0 5.6 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA_14 PF13173.1 EDO07792.1 - 1.5e-09 37.7 0.0 0.011 15.6 0.0 6.9 7 1 0 7 7 6 1 AAA domain AAA_33 PF13671.1 EDO07792.1 - 3e-09 36.8 0.0 0.2 11.5 0.0 6.5 6 0 0 6 6 6 1 AAA domain Miro PF08477.8 EDO07792.1 - 3.3e-07 30.8 0.1 0.36 11.3 0.0 5.4 5 0 0 5 5 5 1 Miro-like protein AAA_19 PF13245.1 EDO07792.1 - 5e-07 29.3 0.8 0.72 9.6 0.0 4.5 4 0 0 4 4 4 2 Part of AAA domain ABC_tran PF00005.22 EDO07792.1 - 8.9e-07 29.2 0.0 0.083 13.1 0.0 5.1 5 0 0 5 5 5 1 ABC transporter MobB PF03205.9 EDO07792.1 - 2.8e-06 27.0 0.1 2.1 8.0 0.0 5.1 5 0 0 5 5 5 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EDO07792.1 - 3.4e-06 26.1 0.1 0.1 11.4 0.0 4.2 4 0 0 4 4 4 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 EDO07792.1 - 3.5e-06 26.3 0.6 3.4 6.7 0.0 6.6 8 1 0 8 8 6 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 EDO07792.1 - 6.1e-06 25.8 1.9 3.2 7.4 0.0 5.2 5 0 0 5 5 5 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EDO07792.1 - 7.9e-06 25.6 1.2 2.1 7.9 0.1 5.1 5 0 0 5 5 5 1 NACHT domain AAA_29 PF13555.1 EDO07792.1 - 2e-05 24.0 0.1 19 4.8 0.0 5.5 5 0 0 5 5 5 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 EDO07792.1 - 2.4e-05 23.8 0.1 1.2 8.6 0.0 4.3 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EDO07792.1 - 2.9e-05 24.4 0.0 0.65 10.2 0.0 3.8 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.17 EDO07792.1 - 0.0002 20.8 0.2 3.3 7.1 0.0 3.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 EDO07792.1 - 0.0002 21.4 0.1 14 5.9 0.0 5.0 5 0 0 5 5 4 0 RNA helicase DUF815 PF05673.8 EDO07792.1 - 0.00022 20.2 0.8 11 4.9 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF815) VWA_2 PF13519.1 EDO07792.1 - 0.00042 20.4 0.0 0.0013 18.8 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Zeta_toxin PF06414.7 EDO07792.1 - 0.00052 19.1 0.0 8.2 5.4 0.0 4.4 4 0 0 4 4 4 0 Zeta toxin Arch_ATPase PF01637.13 EDO07792.1 - 0.00056 19.6 0.2 0.37 10.4 0.0 4.0 5 0 0 5 5 3 1 Archaeal ATPase AAA_30 PF13604.1 EDO07792.1 - 0.0013 18.3 0.0 7.8 6.0 0.0 4.2 4 0 0 4 4 4 0 AAA domain KaiC PF06745.8 EDO07792.1 - 0.0017 17.5 0.0 0.38 9.8 0.0 3.4 3 0 0 3 3 3 1 KaiC IstB_IS21 PF01695.12 EDO07792.1 - 0.002 17.5 0.0 10 5.4 0.0 4.3 4 0 0 4 4 4 0 IstB-like ATP binding protein ResIII PF04851.10 EDO07792.1 - 0.0024 17.7 0.1 2.5 7.8 0.0 2.9 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDO07792.1 - 0.0039 16.6 0.1 15 5.0 0.0 4.3 5 0 0 5 5 5 0 DEAD/DEAH box helicase Dynein_heavy PF03028.10 EDO07792.1 - 0.0043 15.1 0.0 2.6 5.9 0.0 3.4 4 0 0 4 4 4 1 Dynein heavy chain and region D6 of dynein motor AAA_25 PF13481.1 EDO07792.1 - 0.0056 16.1 0.2 11 5.3 0.0 4.0 4 0 0 4 4 4 0 AAA domain ATP-synt_ab PF00006.20 EDO07792.1 - 0.02 14.4 0.0 6.8 6.1 0.0 3.3 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain MCM PF00493.18 EDO07792.1 - 0.021 13.6 0.0 7.3 5.2 0.0 3.7 4 0 0 4 4 3 0 MCM2/3/5 family AAA_PrkA PF08298.6 EDO07792.1 - 0.027 13.1 0.2 1.7 7.2 0.0 3.0 4 0 0 4 4 4 0 PrkA AAA domain RuvB_N PF05496.7 EDO07792.1 - 0.028 13.4 0.3 1.8 7.5 0.0 3.4 4 0 0 4 4 4 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EDO07792.1 - 0.077 12.9 3.2 85 3.0 0.0 4.8 6 0 0 6 6 4 0 AAA domain MarR_2 PF12802.2 EDO07792.1 - 0.15 11.7 0.0 25 4.6 0.0 3.1 2 0 0 2 2 2 0 MarR family PhoH PF02562.11 EDO07792.1 - 0.16 11.2 0.0 5 6.3 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.8 EDO07792.1 - 0.2 10.3 0.0 8.3 5.0 0.0 2.7 2 0 0 2 2 2 0 TIP49 C-terminus Bac_DnaA PF00308.13 EDO07792.1 - 0.51 9.9 0.0 31 4.1 0.0 2.9 3 0 0 3 3 2 0 Bacterial dnaA protein NTPase_1 PF03266.10 EDO07792.1 - 0.52 10.0 1.8 57 3.3 0.0 3.9 4 0 0 4 4 4 0 NTPase MAM33 PF02330.11 EDO07793.1 - 1.6e-19 70.5 1.6 1.8e-15 57.2 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial glycoprotein Peptidase_M24 PF00557.19 EDO07794.1 - 3.1e-42 144.5 0.0 4e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Y_phosphatase3 PF13350.1 EDO07794.1 - 0.05 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family COX15-CtaA PF02628.10 EDO07795.1 - 3.8e-71 239.4 7.2 4.5e-71 239.1 5.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein RNase_H2-Ydr279 PF09468.5 EDO07796.1 - 3.3e-18 65.9 1.5 2e-17 63.3 1.0 1.9 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) VESA1_N PF12785.2 EDO07797.1 - 6.2e-220 730.9 22.8 6.2e-220 730.9 15.8 3.6 4 0 0 4 4 4 1 Variant erythrocyte surface antigen-1 DDE_Tnp_1_assoc PF13808.1 EDO07797.1 - 0.011 15.3 0.0 0.036 13.7 0.0 1.8 1 0 0 1 1 1 0 DDE_Tnp_1-associated PhoU_div PF01865.11 EDO07797.1 - 0.02 14.0 1.2 0.055 12.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF47 Mlp PF03304.8 EDO07797.1 - 0.14 12.1 8.2 3 7.8 0.0 3.3 3 0 0 3 3 3 0 Mlp lipoprotein family DUF948 PF06103.6 EDO07797.1 - 0.17 11.7 3.1 2 8.3 0.3 3.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Mg_chelatase PF01078.16 EDO07797.1 - 0.21 10.7 0.0 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI LXG PF04740.7 EDO07797.1 - 0.53 10.0 2.8 7.1 6.3 0.4 2.9 2 1 0 2 2 2 0 LXG domain of WXG superfamily SF-assemblin PF06705.6 EDO07797.1 - 0.6 9.2 5.8 4.2 6.4 0.3 2.3 2 0 0 2 2 2 0 SF-assemblin/beta giardin VESA1_N PF12785.2 EDO07798.1 - 5e-27 94.9 8.7 5e-27 94.9 6.0 4.3 3 1 1 4 4 4 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO07799.1 - 1.5e-206 686.8 19.6 1.5e-206 686.8 13.6 2.5 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 Pox_A6 PF04924.7 EDO07799.1 - 0.1 11.3 0.2 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A6 protein F-box-like_2 PF13013.1 EDO07800.1 - 1.5e-08 34.3 0.2 2.6e-06 27.1 0.0 2.4 2 1 0 2 2 2 2 F-box-like domain DUF2076 PF09849.4 EDO07801.1 - 0.04 13.9 0.1 0.051 13.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) OppC_N PF12911.2 EDO07802.1 - 0.16 11.3 5.3 1.4 8.3 0.0 3.7 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C VESA1_N PF12785.2 EDO07803.1 - 1.1e-235 782.8 47.7 1e-224 746.7 16.3 3.2 2 1 1 3 3 3 3 Variant erythrocyte surface antigen-1 DDE_Tnp_1_assoc PF13808.1 EDO07803.1 - 0.0052 16.4 0.0 0.032 13.8 0.0 2.3 3 0 0 3 3 3 1 DDE_Tnp_1-associated AAA_13 PF13166.1 EDO07803.1 - 0.56 8.6 4.1 3.1 6.1 0.2 2.2 2 0 0 2 2 2 0 AAA domain ATP-synt_DE PF00401.15 EDO07803.1 - 2.8 7.9 10.9 2.5 8.0 1.0 2.9 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF4175 PF13779.1 EDO07803.1 - 3.7 5.1 8.4 0.12 10.0 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) FIVAR PF07554.8 EDO07803.1 - 8.8 6.6 7.4 2.4 8.4 0.6 2.8 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain DUF2458 PF10454.4 EDO07804.1 - 1.1 9.1 5.3 0.77 9.6 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Med31 PF05669.7 EDO07806.1 - 3.4e-34 116.6 3.9 4e-34 116.4 2.7 1.1 1 0 0 1 1 1 1 SOH1 ubiquitin PF00240.18 EDO07807.1 - 6.8e-07 28.5 0.4 1.8e-06 27.2 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EDO07807.1 - 0.00016 21.8 0.3 0.00052 20.2 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 EDO07807.1 - 0.12 12.1 0.6 0.95 9.1 0.4 2.0 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like zf-DHHC PF01529.15 EDO07808.1 - 9.1e-34 116.3 14.3 9.1e-34 116.3 9.9 2.1 2 1 1 3 3 3 1 DHHC palmitoyltransferase YbjM PF11045.3 EDO07808.1 - 0.012 15.3 0.6 0.012 15.3 0.4 2.2 2 1 0 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae PepSY_TM PF03929.11 EDO07808.1 - 0.033 14.5 5.9 0.3 11.5 0.0 3.3 3 0 0 3 3 3 0 PepSY-associated TM helix DUF2705 PF10920.3 EDO07808.1 - 0.15 11.2 10.0 0.057 12.6 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2705) AtpR PF12966.2 EDO07808.1 - 0.24 11.5 5.2 0.56 10.3 3.6 1.6 1 0 0 1 1 1 0 N-ATPase, AtpR subunit Bromo_TP PF07524.8 EDO07809.1 - 0.00094 18.8 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated DUF3395 PF11875.3 EDO07810.1 - 4.6e-23 81.5 0.0 8.6e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EDO07810.1 - 1.5e-20 72.6 0.7 2.8e-20 71.8 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain TipAS PF07739.8 EDO07810.1 - 0.031 14.5 0.1 0.082 13.2 0.1 1.6 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain IPK PF03770.11 EDO07811.1 - 1.7e-22 80.0 0.0 3.6e-22 78.9 0.0 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase Rib_5-P_isom_A PF06026.9 EDO07812.1 - 1.7e-46 157.7 0.1 2.1e-46 157.4 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EDO07812.1 - 4e-05 23.3 0.2 0.023 14.3 0.1 2.2 1 1 1 2 2 2 2 DeoR C terminal sensor domain Sugar-bind PF04198.8 EDO07812.1 - 0.0085 15.0 0.7 0.021 13.7 0.1 1.8 2 0 0 2 2 2 1 Putative sugar-binding domain DUF2042 PF09743.4 EDO07813.1 - 5e-81 271.9 1.3 2.8e-80 269.5 0.3 2.3 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2042) DUF1213 PF06740.7 EDO07813.1 - 0.51 10.4 2.8 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1213) CTP_transf_2 PF01467.21 EDO07814.1 - 8.8e-18 64.8 0.0 1.1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase TACI-CRD2 PF09305.5 EDO07814.1 - 0.39 10.5 2.3 0.52 10.1 0.0 2.4 3 0 0 3 3 3 0 TACI, cysteine-rich domain AMP-binding PF00501.23 EDO07815.1 - 3.6e-74 249.6 0.0 4.5e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDO07815.1 - 0.012 16.5 0.1 0.032 15.1 0.1 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Methyltransf_31 PF13847.1 EDO07816.1 - 2.1e-10 40.4 0.2 4.1e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDO07816.1 - 3.8e-08 32.7 0.1 6.1e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EDO07816.1 - 1.2e-07 32.2 0.0 3.4e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO07816.1 - 1e-05 25.5 0.0 2.9e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EDO07816.1 - 5.5e-05 22.6 0.1 0.00013 21.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EDO07816.1 - 6.5e-05 23.3 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDO07816.1 - 0.00023 20.7 0.1 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EDO07816.1 - 0.0005 19.8 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO07816.1 - 0.0022 18.3 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EDO07816.1 - 0.0057 16.1 0.1 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EDO07816.1 - 0.0099 15.0 0.1 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 EDO07816.1 - 0.014 14.1 0.0 0.024 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DOT1 PF08123.8 EDO07816.1 - 0.015 14.5 0.1 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Met_10 PF02475.11 EDO07816.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Nudc_N PF14050.1 EDO07817.1 - 6.8e-17 61.1 0.4 1.2e-16 60.3 0.2 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.11 EDO07817.1 - 2.3e-15 56.9 0.0 4.5e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 CS domain KfrA_N PF11740.3 EDO07817.1 - 0.0062 16.9 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term tRNA-synt_1b PF00579.20 EDO07818.1 - 8.5e-25 87.4 0.0 1.4e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-C2HC5 PF06221.8 EDO07819.1 - 5.4e-14 51.6 5.6 5.4e-14 51.6 3.9 1.6 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type PPTA PF01239.17 EDO07820.1 - 4.2e-22 76.4 10.1 5.4e-05 22.3 0.1 4.5 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat COPI_C PF06957.6 EDO07820.1 - 0.1 11.1 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Dehalogenase PF13486.1 EDO07823.1 - 0.058 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Reductive dehalogenase subunit tRNA_m1G_MT PF01746.16 EDO07824.1 - 9.9e-26 90.4 0.0 1.2e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase EGF_MSP1_1 PF12946.2 EDO07824.1 - 0.041 13.6 0.1 0.095 12.4 0.1 1.6 1 0 0 1 1 1 0 MSP1 EGF domain 1 DXP_synthase_N PF13292.1 EDO07825.1 - 7.1e-81 271.0 0.1 1.6e-79 266.6 0.0 2.6 2 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.19 EDO07825.1 - 1.3e-33 116.0 0.1 2.8e-33 114.8 0.1 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EDO07825.1 - 6.9e-18 64.7 0.2 2.5e-17 62.9 0.0 2.0 3 0 0 3 3 3 1 Transketolase, C-terminal domain Transketolase_N PF00456.16 EDO07825.1 - 0.005 15.6 0.1 0.11 11.2 0.0 2.4 3 0 0 3 3 3 1 Transketolase, thiamine diphosphate binding domain Peptidase_M3 PF01432.15 EDO07826.1 - 8.4e-47 160.2 0.0 3.5e-46 158.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M3 Rib PF08428.5 EDO07826.1 - 0.058 13.1 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Rib/alpha-like repeat Ank_2 PF12796.2 EDO07827.1 - 5.7e-42 141.9 0.0 8.8e-17 61.2 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EDO07827.1 - 9.2e-40 132.5 6.2 1.1e-08 34.4 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 EDO07827.1 - 4e-30 100.8 3.0 7.9e-07 28.7 0.0 7.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 EDO07827.1 - 2.5e-28 97.4 7.8 3.4e-08 33.4 0.1 5.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDO07827.1 - 9.5e-28 96.0 1.9 2.2e-09 37.5 0.0 5.8 3 3 2 5 5 5 5 Ankyrin repeats (many copies) TPR_11 PF13414.1 EDO07827.1 - 9.2e-13 47.6 0.0 4.6e-12 45.4 0.0 2.1 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDO07827.1 - 2.6e-05 23.7 0.0 0.078 12.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO07827.1 - 0.00051 19.9 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO07827.1 - 0.0012 18.4 0.1 0.04 13.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDO07827.1 - 0.053 13.1 0.0 0.28 10.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat COPI_assoc PF08507.5 EDO07829.1 - 6.5e-05 22.6 4.7 9.9e-05 22.0 3.3 1.2 1 0 0 1 1 1 1 COPI associated protein CTV_P33 PF07184.6 EDO07829.1 - 0.016 14.0 0.1 0.021 13.6 0.1 1.1 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein SpoVAB PF13782.1 EDO07829.1 - 0.038 13.9 0.3 0.067 13.1 0.2 1.3 1 1 0 1 1 1 0 Stage V sporulation protein AB Anoctamin PF04547.7 EDO07829.1 - 1.3 7.5 5.9 0.45 9.1 1.7 1.7 2 0 0 2 2 2 0 Calcium-activated chloride channel CTP_transf_2 PF01467.21 EDO07830.1 - 0.015 15.3 0.0 0.041 13.9 0.0 1.8 2 0 0 2 2 2 0 Cytidylyltransferase FAD_syn PF06574.7 EDO07830.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase 7TM_GPCR_Sri PF10327.4 EDO07831.1 - 0.012 14.5 0.1 0.022 13.7 0.1 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri zf-A20 PF01754.11 EDO07832.1 - 8.3e-13 47.6 7.8 8.3e-13 47.6 5.4 2.9 4 0 0 4 4 4 1 A20-like zinc finger zf-AN1 PF01428.11 EDO07832.1 - 9.1e-10 38.2 8.2 9.1e-10 38.2 5.7 2.3 3 1 0 3 3 3 1 AN1-like Zinc finger Carla_C4 PF01623.12 EDO07832.1 - 5.4 6.8 8.1 0.55 10.0 1.6 2.0 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein RrnaAD PF00398.15 EDO07834.1 - 1.9e-28 99.2 0.0 2.1e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MA3 PF02847.12 EDO07835.1 - 0.28 10.9 2.4 1.7 8.3 0.2 2.6 2 0 0 2 2 2 0 MA3 domain WD40 PF00400.27 EDO07837.1 - 1.9e-16 59.2 5.1 0.0012 18.6 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EDO07837.1 - 8.3e-11 42.1 1.4 1.5e-10 41.3 0.9 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EDO07837.1 - 0.0095 14.1 0.3 0.031 12.4 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF1230 PF06799.6 EDO07837.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1230) GDI PF00996.13 EDO07838.1 - 1.4e-36 125.8 0.0 2.7e-35 121.5 0.0 2.6 1 1 0 1 1 1 1 GDP dissociation inhibitor Phytoreo_S7 PF07236.6 EDO07838.1 - 0.00014 20.3 0.1 0.00022 19.7 0.1 1.2 1 0 0 1 1 1 1 Phytoreovirus S7 protein Arch_fla_DE PF04659.8 EDO07838.1 - 0.067 12.9 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 Archaeal flagella protein DAN PF03045.10 EDO07838.1 - 0.11 11.8 4.2 1.7 8.0 0.1 2.8 2 1 0 2 2 2 0 DAN domain DUF658 PF04936.7 EDO07839.1 - 0.0039 17.0 2.2 0.0075 16.1 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF658) DUF1777 PF08648.7 EDO07841.1 - 3.8e-24 85.4 40.7 3.8e-24 85.4 28.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) SNF2_N PF00176.18 EDO07842.1 - 1.6e-50 171.6 0.4 8.9e-41 139.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO07842.1 - 1.9e-13 50.0 0.0 1.6e-12 47.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO07842.1 - 8.7e-07 28.5 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDO07842.1 - 7e-06 25.9 1.0 2.5e-05 24.2 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Cpn60_TCP1 PF00118.19 EDO07843.1 - 1.3e-157 525.3 3.0 1.6e-157 525.0 2.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tubulin PF00091.20 EDO07846.1 - 3.4e-70 236.2 0.0 4.7e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDO07846.1 - 1.4e-50 170.5 0.2 2.8e-50 169.5 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain DUF4253 PF14062.1 EDO07846.1 - 0.016 14.8 0.0 0.28 10.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4253) Tubulin_3 PF14881.1 EDO07846.1 - 0.034 13.6 0.0 0.1 12.0 0.0 1.9 1 0 0 1 1 1 0 Tubulin domain Ribosomal_L32e PF01655.13 EDO07847.1 - 3.6e-46 155.7 4.6 4.2e-46 155.5 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Protamine_P2 PF00841.14 EDO07847.1 - 3 8.4 8.9 1.3 9.6 4.1 1.8 2 0 0 2 2 2 0 Sperm histone P2 RabGAP-TBC PF00566.13 EDO07848.1 - 9.6e-18 64.4 1.9 1.6e-17 63.7 0.1 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RasGAP_C PF03836.10 EDO07848.1 - 0.084 12.5 1.6 0.13 11.9 1.1 1.2 1 0 0 1 1 1 0 RasGAP C-terminus Adaptin_N PF01602.15 EDO07849.1 - 4.2e-73 246.4 7.4 4.2e-73 246.4 5.1 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.2 EDO07849.1 - 5.1e-10 39.4 2.2 7.8e-05 22.5 0.0 3.0 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EDO07849.1 - 7.4e-07 28.7 0.1 0.0092 15.9 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EDO07849.1 - 1.4e-06 28.4 0.0 0.0049 17.1 0.0 3.9 3 2 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EDO07849.1 - 9.6e-06 25.9 0.0 0.34 11.4 0.0 3.5 2 0 0 2 2 2 2 HEAT-like repeat Cnd3 PF12719.2 EDO07849.1 - 0.24 10.3 6.3 0.092 11.7 0.2 2.7 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain PH PF00169.24 EDO07850.1 - 0.05 13.8 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 PH domain SPC22 PF04573.7 EDO07851.1 - 1.6e-28 99.1 0.0 1.7e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Prefoldin_2 PF01920.15 EDO07852.1 - 3.3e-16 58.9 9.2 3.8e-16 58.7 6.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit Chibby PF14645.1 EDO07852.1 - 0.0031 17.3 1.0 0.0041 16.9 0.7 1.2 1 0 0 1 1 1 1 Chibby family HR1 PF02185.11 EDO07852.1 - 0.0072 16.0 9.9 0.013 15.1 1.6 2.2 2 0 0 2 2 2 1 Hr1 repeat DUF2353 PF09789.4 EDO07852.1 - 0.0083 15.4 3.8 0.011 15.0 2.6 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Rootletin PF15035.1 EDO07852.1 - 0.0088 16.0 5.8 0.013 15.4 4.0 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Prefoldin PF02996.12 EDO07852.1 - 0.012 15.2 6.1 0.33 10.6 0.5 2.1 2 0 0 2 2 2 0 Prefoldin subunit Sec8_exocyst PF04048.9 EDO07852.1 - 0.017 14.7 3.8 1.5 8.4 0.1 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain MIP-T3 PF10243.4 EDO07852.1 - 0.025 13.0 2.9 0.47 8.8 0.1 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Seryl_tRNA_N PF02403.17 EDO07852.1 - 0.029 14.3 6.9 1.1 9.2 0.3 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc24 PF08286.6 EDO07852.1 - 0.032 13.9 7.9 0.41 10.3 0.7 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Lectin_N PF03954.9 EDO07852.1 - 0.036 13.4 1.0 0.048 13.0 0.7 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain SMP_2 PF10144.4 EDO07852.1 - 0.049 12.7 0.6 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin Sec20 PF03908.8 EDO07852.1 - 0.051 13.2 5.1 0.87 9.3 0.2 2.2 2 0 0 2 2 2 0 Sec20 Snapin_Pallidin PF14712.1 EDO07852.1 - 0.056 13.7 5.8 2.7 8.3 3.7 2.4 1 1 0 1 1 1 0 Snapin/Pallidin GAS PF13851.1 EDO07852.1 - 0.084 12.0 8.2 0.46 9.6 0.8 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3321 PF11968.3 EDO07852.1 - 0.088 12.4 0.9 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase (DUF3321) APG6 PF04111.7 EDO07852.1 - 0.089 11.8 10.7 0.2 10.7 1.5 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EDO07852.1 - 0.09 12.6 11.8 0.2 11.4 1.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 EDO07852.1 - 0.09 12.5 2.4 0.16 11.8 1.7 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus YscO PF07321.7 EDO07852.1 - 0.091 12.5 7.0 0.23 11.2 0.3 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO Ax_dynein_light PF10211.4 EDO07852.1 - 0.1 12.4 7.8 0.31 10.8 0.6 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain Fmp27_WPPW PF10359.4 EDO07852.1 - 0.13 10.6 2.7 0.17 10.2 1.9 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain MCC-bdg_PDZ PF10506.4 EDO07852.1 - 0.14 12.0 2.5 0.23 11.3 0.3 2.2 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4200 PF13863.1 EDO07852.1 - 0.14 12.0 10.3 0.15 11.9 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Noelin-1 PF12308.3 EDO07852.1 - 0.14 11.9 1.3 0.24 11.1 0.4 1.7 1 1 1 2 2 2 0 Neurogenesis glycoprotein V-SNARE PF05008.10 EDO07852.1 - 0.15 12.2 6.0 4.2 7.5 0.7 2.2 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Glyco_tran_28_C PF04101.11 EDO07852.1 - 0.15 11.6 3.9 1.3 8.6 0.2 2.0 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain DUF4140 PF13600.1 EDO07852.1 - 0.15 12.4 5.3 5.2 7.5 0.2 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 EDO07852.1 - 0.16 11.4 9.8 0.52 9.8 0.6 2.2 2 0 0 2 2 2 0 Septum formation initiator Glutaredoxin2_C PF04399.8 EDO07852.1 - 0.2 11.2 4.5 3.8 7.0 0.2 2.1 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain CENP-K PF11802.3 EDO07852.1 - 0.23 10.6 7.2 0.28 10.3 5.0 1.1 1 0 0 1 1 1 0 Centromere-associated protein K DUF406 PF04175.7 EDO07852.1 - 0.24 11.9 4.0 0.2 12.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF406) PspA_IM30 PF04012.7 EDO07852.1 - 0.24 10.7 6.3 1.2 8.4 0.9 2.0 2 0 0 2 2 2 0 PspA/IM30 family DUF2730 PF10805.3 EDO07852.1 - 0.27 10.9 2.4 1.2 8.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) TMF_TATA_bd PF12325.3 EDO07852.1 - 0.28 10.9 11.3 1.2 8.8 1.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding AKNA PF12443.3 EDO07852.1 - 0.29 11.1 4.3 5.3 7.1 0.1 2.5 2 1 0 2 2 2 0 AT-hook-containing transcription factor TMF_DNA_bd PF12329.3 EDO07852.1 - 0.31 10.8 11.9 0.2 11.4 2.5 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1241 PF06840.6 EDO07852.1 - 0.34 10.1 3.6 0.55 9.4 2.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1241) NTR2 PF15458.1 EDO07852.1 - 0.35 10.0 9.5 0.46 9.6 0.5 2.1 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Takusan PF04822.8 EDO07852.1 - 0.35 10.6 7.1 1.4 8.7 0.9 2.3 2 0 0 2 2 2 0 Takusan Fib_alpha PF08702.5 EDO07852.1 - 0.36 10.9 4.7 0.9 9.6 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Viral_P18 PF04521.8 EDO07852.1 - 0.36 10.2 3.5 4.8 6.6 0.3 2.1 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein COG5 PF10392.4 EDO07852.1 - 0.36 10.7 7.1 2.8 7.9 0.2 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 T2SM PF04612.7 EDO07852.1 - 0.38 10.5 3.5 2.2 8.0 0.2 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DivIVA PF05103.8 EDO07852.1 - 0.39 10.7 10.2 0.8 9.7 1.2 2.1 2 0 0 2 2 2 0 DivIVA protein DUF607 PF04678.8 EDO07852.1 - 0.4 10.5 3.2 7.8 6.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF607 DUF3450 PF11932.3 EDO07852.1 - 0.41 9.8 6.5 2.9 7.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Adaptin_binding PF10199.4 EDO07852.1 - 0.42 10.8 4.0 8.8 6.6 0.2 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 IFP_35_N PF07334.8 EDO07852.1 - 0.49 10.4 7.5 3.9 7.5 0.9 2.5 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Spc7 PF08317.6 EDO07852.1 - 0.5 8.9 8.2 0.69 8.5 5.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.3 EDO07852.1 - 0.7 9.7 8.0 2.8 7.8 0.8 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.6 EDO07852.1 - 0.76 9.6 3.2 8.8 6.2 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PCRF PF03462.13 EDO07852.1 - 0.84 9.3 7.9 4 7.1 0.3 2.2 1 1 1 2 2 2 0 PCRF domain DUF3847 PF12958.2 EDO07852.1 - 0.86 9.4 8.6 3.3 7.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) FlxA PF14282.1 EDO07852.1 - 0.86 9.5 8.1 5.7 6.9 1.1 2.2 2 0 0 2 2 2 0 FlxA-like protein P4Ha_N PF08336.6 EDO07852.1 - 0.91 9.3 4.9 1.9 8.3 0.4 2.2 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region H-kinase_dim PF02895.9 EDO07852.1 - 1.1 9.6 6.2 2.7 8.3 0.6 2.2 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain CENP-Q PF13094.1 EDO07852.1 - 1.2 9.1 9.0 1 9.3 0.3 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit YvrJ PF12841.2 EDO07852.1 - 1.2 8.4 4.7 6 6.2 0.5 2.4 2 0 0 2 2 2 0 YvrJ protein family DP PF08781.5 EDO07852.1 - 1.3 8.7 11.5 2.2 7.9 0.9 2.4 2 1 0 2 2 2 0 Transcription factor DP DUF2968 PF11180.3 EDO07852.1 - 1.3 8.3 7.2 2.2 7.6 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) CorA PF01544.13 EDO07852.1 - 1.3 7.9 5.4 2.3 7.1 3.1 1.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein MerR-DNA-bind PF09278.6 EDO07852.1 - 1.8 9.0 6.3 8 6.9 0.2 2.2 2 0 0 2 2 2 0 MerR, DNA binding MRP-L28 PF09812.4 EDO07852.1 - 2 8.1 5.2 3.4 7.4 0.2 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 Fzo_mitofusin PF04799.8 EDO07852.1 - 2.1 7.6 5.1 6.3 6.1 0.3 2.0 2 0 0 2 2 2 0 fzo-like conserved region Nup54 PF13874.1 EDO07852.1 - 2.2 7.9 7.1 18 5.0 4.9 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 ACCA PF03255.9 EDO07852.1 - 2.6 7.5 5.9 4.4 6.8 0.3 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF972 PF06156.8 EDO07852.1 - 4.7 7.6 11.0 5.8 7.3 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 EDO07852.1 - 5.9 6.9 10.3 10 6.1 0.6 2.3 2 0 0 2 2 2 0 bZIP transcription factor Bap31 PF05529.7 EDO07852.1 - 5.9 6.2 9.1 17 4.7 6.3 1.7 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF342 PF03961.8 EDO07852.1 - 6.2 5.1 8.5 12 4.2 5.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) M PF02370.11 EDO07852.1 - 7.5 7.2 17.8 0.63 10.5 2.1 3.2 3 0 0 3 3 2 0 M protein repeat AAA_23 PF13476.1 EDO07852.1 - 8.3 6.6 13.2 13 5.9 8.9 1.5 1 1 0 1 1 1 0 AAA domain OmpH PF03938.9 EDO07852.1 - 9 6.2 8.9 20 5.0 6.1 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Bac_DNA_binding PF00216.16 EDO07853.1 - 1.2e-19 70.1 0.3 1.6e-19 69.7 0.2 1.2 1 0 0 1 1 1 1 Bacterial DNA-binding protein DUF4496 PF14908.1 EDO07853.1 - 0.0015 18.4 0.7 0.049 13.5 0.1 1.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4496) FliG_N PF14842.1 EDO07853.1 - 0.021 14.9 0.3 0.035 14.2 0.2 1.3 1 0 0 1 1 1 0 FliG N-terminal domain Proteasom_PSMB PF10508.4 EDO07853.1 - 0.061 11.5 0.0 0.076 11.2 0.0 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit PfUIS3 PF11567.3 EDO07853.1 - 0.12 12.5 0.1 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein Pkinase PF00069.20 EDO07854.1 - 1.5e-38 132.4 0.0 1.8e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO07854.1 - 5.8e-16 58.3 0.0 7.1e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO07854.1 - 7.1e-06 25.9 0.0 0.002 17.9 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EDO07854.1 - 0.011 14.5 0.2 0.011 14.5 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase SMC_N PF02463.14 EDO07856.1 - 7.3e-48 162.6 0.0 7e-47 159.4 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDO07856.1 - 1.9e-24 85.9 0.0 1.1e-23 83.4 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EDO07856.1 - 2e-15 57.5 0.5 6.4e-07 29.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EDO07856.1 - 2.3e-14 54.2 1.6 2.3e-14 54.2 1.1 4.8 3 2 1 4 4 3 1 AAA domain AAA_15 PF13175.1 EDO07856.1 - 5.5e-11 42.1 0.4 1.6e-05 24.1 1.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.1 EDO07856.1 - 0.00069 18.2 55.3 0.16 10.3 7.7 5.0 3 2 2 5 5 5 5 AAA domain TMF_TATA_bd PF12325.3 EDO07856.1 - 0.0011 18.7 3.3 0.0011 18.7 2.3 8.2 2 2 7 9 9 9 3 TATA element modulatory factor 1 TATA binding DUF948 PF06103.6 EDO07856.1 - 0.0019 18.0 34.4 0.12 12.1 0.7 7.3 8 1 1 9 9 7 3 Bacterial protein of unknown function (DUF948) AAA_25 PF13481.1 EDO07856.1 - 0.0021 17.4 0.0 1.1 8.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain IncA PF04156.9 EDO07856.1 - 0.0038 16.8 82.9 0.01 15.4 3.3 7.4 2 2 4 6 6 6 3 IncA protein AAA_29 PF13555.1 EDO07856.1 - 0.0041 16.6 0.0 0.0088 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EDO07856.1 - 0.0045 17.2 17.3 0.013 15.8 0.0 5.0 4 3 1 5 5 5 2 ABC transporter CENP-F_leu_zip PF10473.4 EDO07856.1 - 0.0046 16.8 11.1 0.0046 16.8 7.7 7.3 2 2 5 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 EDO07856.1 - 0.0062 16.3 4.9 0.0062 16.3 3.4 6.9 2 2 4 6 6 6 3 Autophagy protein 16 (ATG16) Shugoshin_N PF07558.6 EDO07856.1 - 0.0075 15.9 1.1 2.2 8.0 0.1 4.2 2 1 1 3 3 3 1 Shugoshin N-terminal coiled-coil region Reo_sigmaC PF04582.7 EDO07856.1 - 0.071 12.2 57.8 0.61 9.1 0.1 6.6 2 2 5 7 7 7 0 Reovirus sigma C capsid protein WEMBL PF05701.6 EDO07856.1 - 0.32 9.4 70.5 0.13 10.7 10.4 4.7 2 2 1 3 3 3 0 Weak chloroplast movement under blue light DUF3584 PF12128.3 EDO07856.1 - 0.42 7.8 56.8 0.02 12.2 19.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) Laminin_II PF06009.7 EDO07856.1 - 2.6 7.8 60.2 0.14 11.9 2.1 6.7 3 2 4 7 7 7 0 Laminin Domain II Ribosomal_S26e PF01283.14 EDO07858.1 - 6.3e-49 164.9 9.3 7.2e-49 164.7 6.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e SRP19 PF01922.12 EDO07858.1 - 0.039 14.5 0.2 0.1 13.1 0.1 1.9 1 1 0 1 1 1 0 SRP19 protein zf-ribbon_3 PF13248.1 EDO07858.1 - 0.08 12.1 0.1 0.08 12.1 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon domain DNA_pol3_delta2 PF13177.1 EDO07860.1 - 4.3e-14 52.4 0.0 9.9e-14 51.3 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EDO07860.1 - 2e-13 50.6 0.0 4.6e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EDO07860.1 - 8.6e-08 31.2 0.0 4.6e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EDO07860.1 - 3.8e-07 29.9 0.0 8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 EDO07860.1 - 4.3e-07 30.1 0.1 3.1e-06 27.3 0.0 2.3 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EDO07860.1 - 2.8e-06 27.0 0.0 7.8e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDO07860.1 - 9.7e-06 25.2 0.0 2.6e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EDO07860.1 - 1.6e-05 24.5 0.0 3.7e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDO07860.1 - 2.4e-05 24.2 0.0 5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDO07860.1 - 6.3e-05 22.7 0.0 0.00018 21.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO07860.1 - 0.00034 20.6 0.0 0.0011 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EDO07860.1 - 0.0006 18.8 0.0 0.00091 18.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.7 EDO07860.1 - 0.00075 18.6 0.0 0.0017 17.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DEAD PF00270.24 EDO07860.1 - 0.00079 18.9 0.5 0.36 10.2 0.0 2.9 2 2 1 3 3 3 1 DEAD/DEAH box helicase PhoH PF02562.11 EDO07860.1 - 0.0024 17.1 0.5 0.21 10.8 0.0 2.3 1 1 0 2 2 2 1 PhoH-like protein SNF2_N PF00176.18 EDO07860.1 - 0.0035 16.2 0.0 0.027 13.2 0.0 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain TIP49 PF06068.8 EDO07860.1 - 0.0038 16.0 0.0 0.071 11.8 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 EDO07860.1 - 0.0045 16.4 0.0 0.071 12.5 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 EDO07860.1 - 0.0054 17.5 0.0 0.013 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDO07860.1 - 0.0054 16.1 0.1 0.014 14.8 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EDO07860.1 - 0.03 13.9 0.0 0.084 12.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GRDB PF07355.7 EDO07860.1 - 0.032 13.1 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) AAA_28 PF13521.1 EDO07860.1 - 0.034 14.0 0.0 0.085 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EDO07860.1 - 0.038 13.1 0.2 0.22 10.6 0.1 2.2 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EDO07860.1 - 0.049 13.9 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDO07860.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EDO07860.1 - 0.073 12.8 0.0 0.94 9.2 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EDO07860.1 - 0.074 12.4 0.3 1.4 8.2 0.0 2.5 2 1 0 3 3 3 0 AAA-like domain Zot PF05707.7 EDO07860.1 - 0.086 12.3 0.0 0.24 10.8 0.0 1.7 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) PAP2 PF01569.16 EDO07861.1 - 0.031 13.9 0.1 0.042 13.5 0.1 1.1 1 0 0 1 1 1 0 PAP2 superfamily Rad60-SLD_2 PF13881.1 EDO07861.1 - 0.069 13.0 0.0 0.22 11.4 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Mt_ATP-synt_B PF05405.9 EDO07862.1 - 0.011 15.2 3.1 0.022 14.2 2.2 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF445 PF04286.7 EDO07862.1 - 0.068 12.6 0.5 0.097 12.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) RNA_pol PF00940.14 EDO07863.1 - 2.2e-141 471.0 0.0 3.1e-141 470.5 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EDO07863.1 - 1.2e-20 74.0 0.7 4.6e-19 68.8 0.5 2.8 1 1 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Gly-zipper_Omp PF13488.1 EDO07864.1 - 0.00039 19.9 1.2 0.00039 19.9 0.8 2.5 2 0 0 2 2 2 1 Glycine zipper Gly-zipper_YMGG PF13441.1 EDO07864.1 - 0.6 9.6 18.4 0.067 12.7 7.6 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper Beta-APP PF03494.8 EDO07864.1 - 2.9 7.4 7.4 7.3 6.1 5.1 1.7 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Gly-zipper_OmpA PF13436.1 EDO07864.1 - 4.9 6.8 11.7 0.47 10.1 4.1 2.0 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain zf-C3HC4_3 PF13920.1 EDO07865.1 - 4.9e-11 42.1 14.4 1.1e-10 41.0 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO07865.1 - 0.0021 18.0 19.6 0.0058 16.6 13.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Snf7 PF03357.16 EDO07866.1 - 6.2e-18 64.7 14.9 1.3e-17 63.7 10.3 1.6 1 1 0 1 1 1 1 Snf7 DUF512 PF04459.7 EDO07866.1 - 0.031 13.3 0.7 0.057 12.4 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF512) Rho_Binding PF08912.6 EDO07866.1 - 0.16 12.2 3.7 0.11 12.7 0.6 2.2 2 0 0 2 2 2 0 Rho Binding Band_7 PF01145.20 EDO07866.1 - 0.18 11.6 4.6 0.22 11.3 3.2 1.2 1 0 0 1 1 1 0 SPFH domain / Band 7 family CCP_MauG PF03150.9 EDO07866.1 - 0.22 11.8 1.9 0.68 10.2 1.0 1.8 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase NYD-SP28 PF14772.1 EDO07866.1 - 0.7 10.0 9.2 0.062 13.3 0.8 2.7 2 2 0 2 2 2 0 Sperm tail SUI1 PF01253.17 EDO07867.1 - 4.4e-27 93.7 0.1 5.3e-27 93.4 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 GIDA PF01134.17 EDO07868.1 - 3.6e-140 467.2 0.0 6.9e-140 466.3 0.0 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EDO07868.1 - 7.9e-11 41.8 0.0 7e-07 29.2 0.0 2.8 2 0 0 2 2 2 2 GidA associated domain 3 DAO PF01266.19 EDO07868.1 - 1.1e-07 31.1 1.5 0.0034 16.3 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDO07868.1 - 1.8e-07 31.2 0.8 4.9e-07 29.8 0.6 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDO07868.1 - 3.7e-07 29.5 2.8 7.1e-07 28.6 2.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDO07868.1 - 3.7e-06 26.0 5.4 0.00026 19.9 1.7 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 EDO07868.1 - 0.00023 21.4 0.4 0.00069 19.9 0.3 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDO07868.1 - 0.00048 18.7 3.5 0.024 13.1 1.0 3.2 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.7 EDO07868.1 - 0.0022 17.0 1.2 0.054 12.4 0.3 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EDO07868.1 - 0.027 14.5 0.6 0.19 11.7 0.5 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EDO07868.1 - 0.033 13.7 0.1 0.079 12.5 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EDO07868.1 - 0.049 13.3 0.1 0.049 13.3 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EDO07868.1 - 0.088 11.8 0.4 0.17 10.8 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 EDO07868.1 - 0.11 12.5 1.7 0.28 11.2 0.7 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EDO07868.1 - 0.21 10.1 3.4 0.23 10.0 0.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase C2 PF00168.25 EDO07869.1 - 8.3e-08 31.9 0.1 9.7e-07 28.5 0.1 2.7 2 0 0 2 2 2 1 C2 domain ArsR PF09824.4 EDO07869.1 - 0.0075 15.5 0.5 0.02 14.1 0.3 1.7 1 0 0 1 1 1 1 ArsR transcriptional regulator VESA1_N PF12785.2 EDO07870.1 - 9.1e-24 84.2 19.5 4.2e-15 55.6 0.2 4.1 2 1 2 4 4 4 3 Variant erythrocyte surface antigen-1 RRP7 PF12923.2 EDO07871.1 - 1.2e-05 25.2 0.0 2.7e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) DUF3501 PF12007.3 EDO07871.1 - 0.049 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3501) PCI PF01399.22 EDO07872.1 - 9.4e-09 35.5 0.1 2.5e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.1 EDO07872.1 - 0.15 11.8 0.9 0.43 10.4 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDO07872.1 - 0.33 10.9 1.2 0.66 10.0 0.3 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat VESA1_N PF12785.2 EDO07873.1 - 1.9e-21 76.5 28.4 6.1e-12 45.2 0.0 3.7 3 1 1 4 4 4 3 Variant erythrocyte surface antigen-1 FTCD_C PF04961.7 EDO07873.1 - 0.03 13.7 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase VESA1_N PF12785.2 EDO07874.1 - 3.4e-196 652.7 30.7 3.4e-196 652.7 21.3 2.9 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 RBP_receptor PF14752.1 EDO07875.1 - 0.02 13.2 0.0 0.021 13.1 0.0 1.0 1 0 0 1 1 1 0 Retinol binding protein receptor Pkinase PF00069.20 EDO07877.1 - 3.7e-52 177.0 0.0 4.5e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO07877.1 - 2.4e-37 128.4 0.0 3.2e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO07877.1 - 2.1e-07 30.2 0.0 3.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO07877.1 - 0.00013 21.7 0.1 0.044 13.4 0.3 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EDO07877.1 - 0.0088 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EDO07877.1 - 0.14 11.5 0.1 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Abhydrolase_6 PF12697.2 EDO07878.1 - 3.4e-13 49.9 0.0 4.8e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO07878.1 - 3.3e-06 26.9 0.0 4.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO07878.1 - 1.4e-05 24.7 0.0 3.5e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EDO07878.1 - 3.8e-05 22.3 0.0 5.8e-05 21.7 0.0 1.4 1 1 0 1 1 1 1 Ndr family DUF1057 PF06342.7 EDO07878.1 - 0.00064 18.6 0.0 0.001 17.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) PUF PF00806.14 EDO07879.1 - 2.5e-15 54.9 5.2 0.00023 20.4 0.2 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat DUF2854 PF11016.3 EDO07879.1 - 0.03 13.8 0.0 0.078 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) ABC_tran_2 PF12848.2 EDO07879.1 - 1.4 8.7 5.0 20 5.0 0.2 2.5 2 0 0 2 2 2 0 ABC transporter LCM PF04072.9 EDO07880.1 - 4e-17 62.3 0.0 5.1e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase MTS PF05175.9 EDO07880.1 - 3.3e-05 23.3 0.0 4.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain SSrecog PF03531.9 EDO07881.1 - 1.3e-49 168.5 0.3 2.1e-49 167.8 0.2 1.3 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EDO07881.1 - 4.4e-25 87.4 4.2 2.4e-24 85.1 0.1 3.5 4 0 0 4 4 4 1 Histone chaperone Rttp106-like KTSC PF13619.1 EDO07881.1 - 0.24 11.0 2.5 0.82 9.3 0.0 3.0 4 0 0 4 4 4 0 KTSC domain DUF2457 PF10446.4 EDO07881.1 - 0.68 8.6 15.6 0.81 8.3 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1676 PF07898.8 EDO07881.1 - 1.2 9.4 8.3 0.61 10.4 3.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1676) NOA36 PF06524.7 EDO07881.1 - 2.7 7.1 10.6 3.7 6.7 7.3 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L1 PF00687.16 EDO07882.1 - 1.6e-48 164.9 1.7 1.9e-48 164.7 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Nbl1_Borealin_N PF10444.4 EDO07882.1 - 0.059 12.7 0.3 0.72 9.2 0.0 2.5 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal DUF4368 PF14287.1 EDO07882.1 - 0.076 12.8 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) Pox_Ag35 PF03286.9 EDO07883.1 - 0.17 11.3 17.7 0.22 11.0 12.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2392 PF10288.4 EDO07884.1 - 0.00018 21.8 0.2 0.00055 20.2 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2392) SpvB PF03534.8 EDO07884.1 - 0.027 13.5 0.1 0.04 12.9 0.1 1.2 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein RVT_1 PF00078.22 EDO07884.1 - 0.051 12.9 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 EDO07885.1 - 1.1e-60 205.0 0.0 1.5e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO07885.1 - 2.5e-30 105.4 0.0 4.6e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDO07885.1 - 5.4e-05 22.3 0.0 9.8e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDO07885.1 - 0.041 12.8 0.0 3.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like WD40 PF00400.27 EDO07886.1 - 9e-05 22.2 0.7 0.85 9.6 0.1 3.4 3 1 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EDO07886.1 - 0.0077 15.0 2.3 0.011 14.4 1.6 1.5 1 1 0 1 1 1 1 Nup133 N terminal like PQQ_2 PF13360.1 EDO07886.1 - 0.03 13.7 0.1 0.1 12.0 0.1 1.7 1 1 0 1 1 1 0 PQQ-like domain PQQ_3 PF13570.1 EDO07886.1 - 0.069 13.4 5.4 0.51 10.6 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain Cadherin-like PF12733.2 EDO07886.1 - 0.13 12.5 0.2 0.32 11.2 0.1 1.7 1 1 0 1 1 1 0 Cadherin-like beta sandwich domain WD40 PF00400.27 EDO07887.1 - 1.2e-14 53.5 8.7 7.2e-06 25.6 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 EDO07887.1 - 0.0065 14.6 1.1 0.78 7.8 0.1 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 RRM_1 PF00076.17 EDO07888.1 - 4.4e-06 26.2 0.0 9.2e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07888.1 - 5.4e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07888.1 - 0.0046 16.7 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDO07888.1 - 0.088 12.6 0.4 8.4 6.2 0.0 2.7 3 1 0 3 3 3 0 RNA binding motif DUF1383 PF07134.6 EDO07889.1 - 0.032 13.1 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) Tmemb_cc2 PF10267.4 EDO07889.1 - 0.095 11.2 0.3 0.16 10.5 0.2 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Aldo_ket_red PF00248.16 EDO07890.1 - 1.1e-57 194.9 0.0 1.7e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Biotin_lipoyl PF00364.17 EDO07891.1 - 3.2e-15 55.5 0.6 5.2e-15 54.8 0.4 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EDO07891.1 - 6.5e-06 25.7 1.3 0.024 14.2 0.1 2.3 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.14 EDO07891.1 - 0.045 13.4 0.1 0.16 11.6 0.1 1.9 1 1 0 1 1 1 0 Glycine cleavage H-protein Imm18 PF15566.1 EDO07893.1 - 0.6 9.4 4.1 1.6 8.1 2.8 1.8 1 1 0 1 1 1 0 Immunity protein 18 APG6 PF04111.7 EDO07893.1 - 0.68 8.9 8.6 1.1 8.2 6.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EDO07893.1 - 9.1 5.8 10.9 10 5.6 5.3 2.4 1 1 1 2 2 2 0 IncA protein DUF1641 PF07849.6 EDO07894.1 - 0.0093 15.5 0.0 4 7.1 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1641) Ribosomal_L12 PF00542.14 EDO07895.1 - 3e-06 27.1 2.1 4.4e-06 26.5 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EDO07895.1 - 0.0087 16.4 1.2 0.0087 16.4 0.8 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein Tom22 PF04281.8 EDO07896.1 - 1.5e-07 31.0 0.1 1.7e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 CinA PF02464.12 EDO07896.1 - 0.096 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Competence-damaged protein Glyco_hydro_31 PF01055.21 EDO07896.1 - 0.12 11.1 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 zf-U1 PF06220.7 EDO07897.1 - 2.6e-18 65.2 2.4 3.6e-18 64.8 1.7 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EDO07897.1 - 0.03 14.4 2.9 0.054 13.6 2.0 1.5 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Adenine_glyco PF03352.8 EDO07898.1 - 0.073 12.5 0.1 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyladenine glycosylase ArfGap PF01412.13 EDO07899.1 - 0.011 15.5 0.9 0.02 14.6 0.6 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Nudc_N PF14050.1 EDO07901.1 - 3.5e-20 71.7 1.3 6e-20 70.9 0.9 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.11 EDO07901.1 - 1.5e-12 47.8 0.9 2.5e-12 47.1 0.1 1.8 2 0 0 2 2 2 1 CS domain TRAPPC10 PF12584.3 EDO07901.1 - 0.0051 16.3 0.1 0.0075 15.7 0.1 1.3 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DUF4365 PF14280.1 EDO07901.1 - 0.0084 15.8 0.3 0.036 13.7 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4365) UQ_con PF00179.21 EDO07902.1 - 3.1e-48 162.7 0.0 3.6e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDO07902.1 - 0.0014 18.4 0.1 0.0026 17.6 0.1 1.7 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EDO07902.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B RRM_1 PF00076.17 EDO07903.1 - 3.5e-16 58.6 0.0 5.7e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07903.1 - 1.4e-11 44.2 0.0 2.3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07903.1 - 1.3e-08 34.5 0.0 2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Parvo_coat PF00740.13 EDO07903.1 - 0.021 13.8 0.1 0.026 13.4 0.1 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Arf PF00025.16 EDO07905.1 - 1.6e-17 63.3 0.0 2.3e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDO07905.1 - 9.8e-08 31.4 0.0 1.4e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EDO07905.1 - 0.0025 17.7 0.1 0.046 13.6 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase MFS_1 PF07690.11 EDO07906.1 - 7.2e-21 74.2 49.4 2.7e-20 72.3 32.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 EDO07906.1 - 0.76 9.8 12.7 0.24 11.4 1.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) CLTH PF10607.4 EDO07907.1 - 2.4e-23 82.4 0.0 4.1e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain ATP_bind_2 PF03668.10 EDO07907.1 - 0.074 12.1 0.2 0.13 11.2 0.2 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family ER_lumen_recept PF00810.13 EDO07908.1 - 8.2e-35 120.4 9.0 8.2e-35 120.4 6.2 2.4 3 0 0 3 3 3 1 ER lumen protein retaining receptor Colicin_im PF03857.8 EDO07908.1 - 0.18 11.5 0.2 0.18 11.5 0.1 2.8 2 2 0 3 3 3 0 Colicin immunity protein BPD_transp_1 PF00528.17 EDO07908.1 - 2.9 7.3 7.9 0.6 9.5 0.1 2.6 3 0 0 3 3 3 0 Binding-protein-dependent transport system inner membrane component PIG-U PF06728.8 EDO07909.1 - 1.7e-13 50.2 11.2 2e-13 49.9 7.8 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF4342 PF14242.1 EDO07909.1 - 0.48 10.2 4.0 0.96 9.2 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4342) TMC PF07810.8 EDO07909.1 - 0.86 10.0 4.5 10 6.6 0.3 2.4 1 1 1 2 2 2 0 TMC domain DUF663 PF04950.7 EDO07910.1 - 1.8e-72 243.8 0.0 3.1e-72 243.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EDO07910.1 - 8.4e-25 86.1 0.0 3.4e-24 84.1 0.0 2.1 2 0 0 2 2 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EDO07910.1 - 7.9e-06 25.4 0.0 0.00016 21.1 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EDO07910.1 - 1.7e-05 24.0 0.0 3.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EDO07910.1 - 1.8e-05 25.5 0.3 9.5e-05 23.2 0.0 2.5 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EDO07910.1 - 0.00013 21.4 0.0 0.014 14.7 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 EDO07910.1 - 0.00031 20.7 0.1 0.0014 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 EDO07910.1 - 0.00063 20.0 0.2 0.0025 18.1 0.0 2.1 2 0 0 2 2 1 1 ABC transporter RNA_helicase PF00910.17 EDO07910.1 - 0.0011 19.0 0.0 0.0052 16.9 0.0 2.3 1 0 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.18 EDO07910.1 - 0.0021 18.0 0.1 0.0079 16.1 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EDO07910.1 - 0.0021 17.7 0.1 0.0058 16.3 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EDO07910.1 - 0.0023 17.5 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_10 PF12846.2 EDO07910.1 - 0.0034 16.8 0.7 0.018 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 EDO07910.1 - 0.0088 15.9 0.0 0.04 13.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EDO07910.1 - 0.0091 15.9 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO07910.1 - 0.011 16.0 1.9 0.023 15.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EDO07910.1 - 0.014 15.5 0.0 0.041 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EDO07910.1 - 0.015 15.7 0.1 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 EDO07910.1 - 0.019 13.9 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 Septin AAA PF00004.24 EDO07910.1 - 0.023 14.9 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EDO07910.1 - 0.024 14.3 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 EDO07910.1 - 0.027 13.9 0.0 0.071 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EDO07910.1 - 0.029 14.0 0.2 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.10 EDO07910.1 - 0.033 12.8 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein NTPase_1 PF03266.10 EDO07910.1 - 0.037 13.7 0.1 0.081 12.6 0.1 1.6 1 0 0 1 1 1 0 NTPase Guanylate_kin PF00625.16 EDO07910.1 - 0.041 13.3 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase KAP_NTPase PF07693.9 EDO07910.1 - 0.085 11.8 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.12 EDO07910.1 - 0.11 12.0 0.1 0.27 10.7 0.1 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.14 EDO07910.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain zf-CW PF07496.10 EDO07911.1 - 4.8e-17 61.3 6.6 9.5e-17 60.4 4.6 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger EF-hand_7 PF13499.1 EDO07912.1 - 1e-20 73.6 1.8 9.4e-11 41.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EDO07912.1 - 3.6e-19 66.5 6.5 2e-07 29.8 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EDO07912.1 - 1.7e-18 64.7 2.6 3.1e-06 26.5 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EDO07912.1 - 3.3e-18 65.0 4.4 3.4e-10 39.3 0.2 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EDO07912.1 - 9.2e-08 31.1 0.8 0.032 13.5 0.1 3.9 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EDO07912.1 - 0.0021 17.9 0.5 0.76 9.7 0.0 3.0 1 1 2 3 3 3 1 EF-hand domain Acetyltransf_11 PF13720.1 EDO07912.1 - 0.042 14.0 0.1 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 EF-hand_4 PF12763.2 EDO07912.1 - 0.095 12.4 1.1 2.2 8.0 0.1 2.5 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Sigma70_r1_1 PF03979.9 EDO07912.1 - 0.42 10.5 2.9 1.6 8.7 1.0 2.5 1 1 1 2 2 2 0 Sigma-70 factor, region 1.1 IspD PF01128.14 EDO07913.1 - 1e-35 123.2 0.0 6.9e-34 117.2 0.0 2.3 2 0 0 2 2 2 2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Ribophorin_I PF04597.9 EDO07914.1 - 1.7e-19 69.6 4.2 2.1e-19 69.3 2.9 1.1 1 0 0 1 1 1 1 Ribophorin I ASF1_hist_chap PF04729.8 EDO07914.1 - 0.024 14.2 1.5 0.65 9.6 0.0 3.2 3 1 0 3 3 3 0 ASF1 like histone chaperone Asp PF00026.18 EDO07915.1 - 5.1e-70 236.2 0.0 8.5e-69 232.2 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDO07915.1 - 3.6e-06 27.0 0.0 1.1e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EDO07915.1 - 0.003 18.0 0.0 0.76 10.3 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease Alpha-amylase_C PF02806.13 EDO07915.1 - 0.064 13.4 0.2 0.48 10.5 0.0 2.4 2 1 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain V-SNARE PF05008.10 EDO07916.1 - 0.25 11.5 4.0 0.084 13.0 0.7 1.8 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus dsDNA_bind PF01984.15 EDO07918.1 - 2.2e-18 66.2 11.3 2.7e-18 65.8 7.8 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF1376 PF07120.6 EDO07918.1 - 0.027 14.5 0.1 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) Selenoprotein_S PF06936.6 EDO07918.1 - 1.4 8.4 8.8 0.55 9.7 2.3 2.1 1 1 0 2 2 2 0 Selenoprotein S (SelS) Ribosomal_S27e PF01667.12 EDO07920.1 - 3.3e-25 87.3 5.3 4.2e-25 87.0 3.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.7 EDO07920.1 - 0.0018 17.5 1.1 0.0044 16.3 0.5 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding IBR PF01485.16 EDO07920.1 - 0.0046 16.7 0.1 0.0074 16.1 0.1 1.3 1 0 0 1 1 1 1 IBR domain zf-LSD1 PF06943.7 EDO07920.1 - 0.0055 16.2 1.1 0.81 9.3 0.1 2.6 2 1 0 2 2 2 2 LSD1 zinc finger zinc_ribbon_4 PF13717.1 EDO07920.1 - 0.29 10.8 1.6 3.7 7.3 1.1 2.6 1 1 0 1 1 1 0 zinc-ribbon domain Ribosomal_L24e PF01246.15 EDO07921.1 - 2.6e-21 75.2 1.8 2.6e-21 75.2 1.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2992 PF11208.3 EDO07921.1 - 0.9 9.4 9.5 1.3 8.9 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF2188 PF09954.4 EDO07921.1 - 1.7 8.5 5.4 4.9 7.1 3.8 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) DCP2 PF05026.8 EDO07922.1 - 6.6e-21 74.0 2.4 4.4e-20 71.3 0.5 2.3 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.23 EDO07922.1 - 5.8e-15 55.1 0.0 1.1e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CPSase_L_D2 PF02786.12 EDO07923.1 - 2.4e-83 278.5 0.0 3.9e-63 212.5 0.0 2.9 2 1 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 EDO07923.1 - 1.1e-43 149.0 0.0 3.6e-43 147.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EDO07923.1 - 2.1e-41 140.5 0.0 5e-41 139.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.14 EDO07923.1 - 5.3e-38 129.5 0.0 9.7e-38 128.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EDO07923.1 - 4.1e-36 123.4 0.0 1.3e-16 60.6 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EDO07923.1 - 4.7e-24 85.1 0.0 1.4e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDO07923.1 - 1.7e-17 63.1 0.1 8.4e-13 47.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.8 EDO07923.1 - 1.3e-10 41.1 0.8 8.1e-09 35.2 0.1 2.7 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp PF02222.17 EDO07923.1 - 2e-10 40.2 0.0 5.3e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDO07923.1 - 7.3e-08 32.0 1.0 0.00011 21.7 0.1 3.4 3 0 0 3 3 3 1 D-ala D-ala ligase C-terminus MGS PF02142.17 EDO07923.1 - 1.2e-06 28.3 0.0 1.3e-05 24.9 0.0 2.7 1 1 0 1 1 1 1 MGS-like domain RimK PF08443.6 EDO07923.1 - 0.00044 19.7 0.0 0.02 14.3 0.0 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Pkinase PF00069.20 EDO07924.1 - 6.7e-63 212.2 0.0 1e-62 211.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO07924.1 - 2.7e-27 95.4 0.0 3.9e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO07924.1 - 2.6e-05 23.3 0.0 0.00081 18.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EDO07924.1 - 0.0017 17.4 0.0 0.0029 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO07924.1 - 0.0033 17.2 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDO07924.1 - 0.02 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EDO07924.1 - 0.037 12.6 0.3 0.29 9.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) SAC3_GANP PF03399.11 EDO07925.1 - 1.6e-27 96.3 0.7 2.2e-27 95.9 0.5 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EDO07925.1 - 2.7e-13 49.8 0.1 5.5e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 zf-RING_2 PF13639.1 EDO07926.1 - 1.4e-11 44.0 7.0 3e-11 42.9 4.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDO07926.1 - 1.4e-07 31.0 4.4 3e-07 29.9 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO07926.1 - 3.8e-07 30.0 6.8 1e-06 28.6 4.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO07926.1 - 2.2e-06 27.2 6.7 4.6e-06 26.1 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDO07926.1 - 3.4e-06 27.0 5.5 7.6e-06 25.9 3.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EDO07926.1 - 1.5e-05 24.6 6.0 3.1e-05 23.6 4.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EDO07926.1 - 0.004 16.7 3.8 0.0092 15.5 2.6 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 EDO07926.1 - 0.026 14.3 1.5 0.053 13.3 1.1 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 EDO07926.1 - 0.09 12.5 1.6 0.29 10.8 1.1 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EDO07926.1 - 0.15 11.8 4.8 0.51 10.2 3.3 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EDO07926.1 - 0.84 9.7 8.0 1.8 8.6 5.6 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EDO07926.1 - 1 9.3 8.7 7.3 6.6 6.0 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-P11 PF03854.9 EDO07926.1 - 2 7.9 6.8 7.2 6.1 4.7 2.1 1 1 0 1 1 1 0 P-11 zinc finger Sensor PF13796.1 EDO07927.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative sensor WD40 PF00400.27 EDO07928.1 - 4.2e-08 32.7 9.2 2.1e-07 30.5 0.0 5.1 6 0 0 6 6 6 1 WD domain, G-beta repeat Proteasome PF00227.21 EDO07928.1 - 0.072 12.3 0.1 0.25 10.6 0.0 1.9 3 0 0 3 3 3 0 Proteasome subunit MMtag PF10159.4 EDO07930.1 - 2.5e-21 75.4 0.8 3.8e-21 74.9 0.5 1.3 1 0 0 1 1 1 1 Kinase phosphorylation protein WD40 PF00400.27 EDO07931.1 - 6.3e-08 32.2 9.2 2.3e-07 30.4 0.0 5.0 6 0 0 6 6 6 1 WD domain, G-beta repeat Proteasome PF00227.21 EDO07931.1 - 0.069 12.4 0.1 0.22 10.7 0.0 1.8 3 0 0 3 3 3 0 Proteasome subunit Abhydrolase_5 PF12695.2 EDO07932.1 - 3.4e-05 23.6 0.0 5.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO07932.1 - 0.0046 16.8 0.0 0.017 15.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1286 PF06939.6 EDO07932.1 - 0.024 14.7 0.2 0.089 12.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1286) UPF0449 PF15136.1 EDO07933.1 - 0.042 14.0 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Paf67 PF10255.4 EDO07936.1 - 4.4e-138 460.5 4.9 5.4e-138 460.2 3.4 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EDO07936.1 - 0.068 13.1 0.1 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat IBN_N PF03810.14 EDO07937.1 - 2e-07 30.7 0.2 1.6e-06 27.8 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain RIX1 PF08167.7 EDO07937.1 - 3.4e-06 26.8 2.5 9.6e-05 22.1 0.3 3.4 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis TFIIA PF03153.8 EDO07937.1 - 0.021 14.7 2.0 0.031 14.1 1.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNARE PF05739.14 EDO07938.1 - 4.2e-12 45.5 1.9 6.9e-12 44.8 0.4 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EDO07938.1 - 1.9e-07 31.1 1.5 9e-07 29.0 0.2 2.2 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 EDO07938.1 - 1e-05 25.4 2.3 1e-05 25.4 1.6 2.5 2 2 0 2 2 2 1 Syntaxin-like protein SCPU PF05229.10 EDO07938.1 - 0.052 13.6 0.5 0.097 12.7 0.4 1.4 1 0 0 1 1 1 0 Spore Coat Protein U domain AAA_13 PF13166.1 EDO07938.1 - 0.15 10.4 5.7 0.062 11.7 2.3 1.5 1 1 0 1 1 1 0 AAA domain Spc24 PF08286.6 EDO07938.1 - 0.2 11.3 3.5 2.7 7.7 0.3 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 MCM_N PF14551.1 EDO07938.1 - 0.23 11.9 1.2 0.52 10.8 0.8 1.9 1 1 0 1 1 1 0 MCM N-terminal domain Lipoprotein_6 PF01441.14 EDO07938.1 - 0.34 10.7 7.3 0.24 11.2 2.6 2.4 2 1 0 2 2 2 0 Lipoprotein FliE PF02049.13 EDO07938.1 - 1 9.4 5.2 0.51 10.4 0.2 2.8 3 1 0 3 3 3 0 Flagellar hook-basal body complex protein FliE WD40 PF00400.27 EDO07939.1 - 7.2e-14 51.0 5.4 3.7e-09 36.1 0.0 3.9 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EDO07939.1 - 0.0097 14.0 0.0 0.015 13.4 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDO07939.1 - 0.11 11.2 0.1 0.55 8.9 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like AP2 PF00847.15 EDO07940.1 - 7.4e-11 42.0 1.2 1.1e-10 41.5 0.9 1.3 1 0 0 1 1 1 1 AP2 domain SMI1_KNR4 PF09346.5 EDO07941.1 - 0.046 13.7 0.8 0.21 11.5 0.6 2.0 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) EmrE PF13536.1 EDO07942.1 - 0.019 15.1 4.5 0.019 15.1 3.1 2.7 3 1 0 3 3 3 0 Multidrug resistance efflux transporter CAP PF00188.21 EDO07943.1 - 2.5e-17 63.5 0.1 3.3e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ribosomal_S14 PF00253.16 EDO07944.1 - 8.2e-18 63.5 4.0 8.6e-18 63.4 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EDO07944.1 - 0.0092 15.7 0.1 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) zf-C3HC4_3 PF13920.1 EDO07944.1 - 0.094 12.4 0.6 11 5.7 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.9 EDO07944.1 - 0.11 12.0 1.1 0.13 11.7 0.8 1.2 1 0 0 1 1 1 0 P-11 zinc finger DnaJ-X PF14308.1 EDO07945.1 - 7.7e-54 182.0 2.8 7.7e-54 182.0 1.9 1.9 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EDO07945.1 - 8.8e-23 79.8 0.4 1.8e-22 78.8 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.6 EDO07945.1 - 0.016 15.3 0.0 0.088 12.9 0.0 2.3 1 0 0 1 1 1 0 ATG C terminal domain Peptidase_M16 PF00675.15 EDO07948.1 - 7.4e-29 100.4 0.0 7.6e-28 97.1 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDO07948.1 - 7e-28 97.5 0.0 1.3e-27 96.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Tmemb_40 PF10160.4 EDO07948.1 - 0.091 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein Reo_sigmaC PF04582.7 EDO07949.1 - 9.3e-06 25.0 26.7 6.6e-05 22.2 1.9 3.5 1 1 3 4 4 4 3 Reovirus sigma C capsid protein AAA_13 PF13166.1 EDO07949.1 - 2.4e-05 23.0 19.1 2.4e-05 23.0 13.3 2.1 1 1 0 2 2 2 1 AAA domain Laminin_I PF06008.9 EDO07949.1 - 0.0017 17.7 7.9 0.0017 17.7 5.5 4.4 1 1 2 3 3 3 1 Laminin Domain I BLOC1_2 PF10046.4 EDO07949.1 - 0.0088 16.1 2.9 0.0088 16.1 2.0 5.3 1 1 3 6 6 6 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.3 EDO07949.1 - 0.064 10.5 49.7 0.056 10.7 7.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) RICH PF05062.7 EDO07949.1 - 0.43 10.7 11.1 0.39 10.8 0.9 3.6 2 1 1 3 3 3 0 RICH domain BicD PF09730.4 EDO07949.1 - 0.81 7.9 47.3 0.013 13.8 4.2 3.0 2 1 1 3 3 3 0 Microtubule-associated protein Bicaudal-D ATG16 PF08614.6 EDO07949.1 - 1.3 8.7 54.9 3.4 7.4 7.4 5.1 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Vac_Fusion PF02346.11 EDO07949.1 - 5.1 6.6 14.4 0.38 10.2 0.7 4.9 5 1 0 5 5 5 0 Chordopoxvirus fusion protein ADIP PF11559.3 EDO07949.1 - 5.5 6.8 56.3 0.94 9.3 4.1 5.3 2 2 2 5 5 5 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 EDO07949.1 - 5.6 5.5 50.8 0.42 9.2 14.5 4.0 1 1 3 4 4 4 0 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 EDO07949.1 - 6.3 4.3 55.8 0.37 8.4 8.2 3.2 1 1 1 2 2 2 0 Myosin tail zf-CCCH PF00642.19 EDO07950.1 - 5e-08 32.4 19.1 2.1e-05 24.0 3.0 5.0 4 1 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EDO07950.1 - 2.6 8.1 17.1 11 6.1 1.0 4.6 4 1 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type DEAD PF00270.24 EDO07951.1 - 2.7e-29 101.8 0.0 6.1e-29 100.6 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase SPRY PF00622.23 EDO07951.1 - 1.6e-15 57.3 0.4 2.8e-15 56.4 0.3 1.4 1 0 0 1 1 1 1 SPRY domain Helicase_C PF00271.26 EDO07951.1 - 5.1e-15 55.1 0.0 1e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain G10 PF01125.12 EDO07952.1 - 7.8e-65 216.8 1.4 8.8e-65 216.6 1.0 1.0 1 0 0 1 1 1 1 G10 protein DUF1364 PF07102.7 EDO07952.1 - 1.9 8.4 9.7 1.5 8.7 5.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1364) Archease PF01951.11 EDO07954.1 - 1.3e-51 174.1 0.1 1.6e-51 173.8 0.1 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Ribosomal_L18e PF00828.14 EDO07955.1 - 1.8e-12 47.7 2.5 3e-12 47.0 0.3 2.5 2 1 0 2 2 2 1 Ribosomal protein L18e/L15 Ribosomal_L17 PF01196.14 EDO07956.1 - 2.9e-23 82.2 0.5 3.8e-23 81.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 AFG1_ATPase PF03969.11 EDO07957.1 - 1.3e-67 228.1 0.6 1.7e-65 221.1 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.13 EDO07957.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial dnaA protein AAA PF00004.24 EDO07957.1 - 0.023 14.9 0.0 0.059 13.5 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO07957.1 - 0.063 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EDO07957.1 - 0.079 13.2 0.0 1.4 9.1 0.0 2.6 2 1 0 3 3 3 0 ABC transporter AAA_29 PF13555.1 EDO07957.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Chromo PF00385.19 EDO07958.1 - 9.6e-19 66.8 6.1 1.5e-13 50.1 0.2 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Hid1 PF12722.2 EDO07958.1 - 0.032 11.9 7.0 0.04 11.6 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 EDO07958.1 - 0.068 11.5 3.5 0.075 11.4 2.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pox_Ag35 PF03286.9 EDO07958.1 - 0.45 10.0 11.1 0.87 9.0 7.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein LON PF02190.11 EDO07959.1 - 8.5e-08 32.1 0.2 2e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain Hydant_A_N PF05378.8 EDO07959.1 - 0.029 13.8 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region PUB PF09409.5 EDO07960.1 - 1.2e-11 44.2 0.4 5.8e-11 41.9 0.1 2.3 3 0 0 3 3 3 1 PUB domain 7TMR-HDED PF07697.6 EDO07960.1 - 0.011 15.5 0.8 0.017 14.8 0.6 1.4 1 0 0 1 1 1 0 7TM-HD extracellular Baculo_p24 PF05073.7 EDO07960.1 - 0.034 13.7 0.7 1.1 8.7 0.0 2.6 1 1 1 2 2 2 0 Baculovirus P24 capsid protein HAP1_N PF04849.8 EDO07960.1 - 1.3 7.8 7.2 1.9 7.3 1.4 2.3 3 0 0 3 3 3 0 HAP1 N-terminal conserved region WBS_methylT PF12589.3 EDO07963.1 - 4.4e-17 62.3 6.6 6.6e-17 61.7 4.6 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EDO07963.1 - 8.5e-12 45.4 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO07963.1 - 2.3e-08 33.7 0.0 2.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO07963.1 - 2.2e-05 24.8 0.0 5.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO07963.1 - 3.9e-05 23.9 0.0 8e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO07963.1 - 0.00011 22.7 0.0 0.00028 21.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO07963.1 - 0.00053 19.7 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EDO07963.1 - 0.0024 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EDO07963.1 - 0.035 13.4 0.0 0.083 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 EDO07963.1 - 0.036 13.6 0.2 0.07 12.6 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EDO07963.1 - 0.064 12.9 0.3 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EDO07963.1 - 0.066 12.2 0.4 0.11 11.5 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_26 PF13659.1 EDO07963.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.13 EDO07963.1 - 0.077 12.4 0.7 0.41 10.1 0.0 2.2 2 1 0 2 2 2 0 DNA methylase U3_assoc_6 PF08640.6 EDO07964.1 - 8.7e-20 70.2 2.2 1.9e-19 69.1 1.5 1.6 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 DnaJ PF00226.26 EDO07965.1 - 2.2e-16 59.3 1.6 5.5e-16 58.0 1.1 1.8 1 0 0 1 1 1 1 DnaJ domain Sds3 PF08598.6 EDO07965.1 - 5.2 6.5 20.2 1.1 8.7 9.6 2.5 1 1 1 2 2 2 0 Sds3-like UQ_con PF00179.21 EDO07966.1 - 2.7e-19 68.9 0.0 3.2e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDO07966.1 - 0.011 15.6 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain NIF PF03031.13 EDO07967.1 - 1.9e-46 157.6 0.1 2.8e-46 157.0 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase FB_lectin PF07367.6 EDO07967.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Fungal fruit body lectin RNA_pol_L_2 PF13656.1 EDO07968.1 - 1.3e-12 46.9 0.0 1.8e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain AP2 PF00847.15 EDO07972.1 - 2.3e-07 30.8 0.3 0.0038 17.3 0.0 2.6 2 0 0 2 2 2 2 AP2 domain V-ATPase_H_C PF11698.3 EDO07973.1 - 3e-46 156.1 0.2 1.3e-45 154.0 0.2 2.1 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 EDO07973.1 - 2e-38 132.3 0.5 2.7e-38 131.8 0.4 1.2 1 0 0 1 1 1 1 V-ATPase subunit H Arm PF00514.18 EDO07973.1 - 0.0059 16.3 0.0 3.4 7.6 0.0 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat DUF310 PF03750.8 EDO07973.1 - 0.0082 16.3 0.0 0.12 12.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF310) RED_N PF07808.8 EDO07974.1 - 1.4e-18 67.0 8.5 1.4e-18 67.0 5.9 2.8 2 1 0 2 2 2 1 RED-like protein N-terminal region RRM_1 PF00076.17 EDO07975.1 - 1.6e-17 62.9 0.2 1.9e-08 33.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO07975.1 - 1.2e-16 60.4 0.4 1.5e-07 31.2 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO07975.1 - 9.9e-14 50.9 0.3 1e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3452 PF11934.3 EDO07977.1 - 0.061 12.6 1.0 0.22 10.8 0.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) TyeA PF09059.5 EDO07977.1 - 0.19 11.6 2.2 0.67 9.9 0.4 2.6 2 0 0 2 2 2 0 TyeA YfkB PF08756.5 EDO07981.1 - 0.043 13.3 0.2 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 YfkB-like domain Arf PF00025.16 EDO07985.1 - 4.7e-74 247.3 0.2 5.4e-74 247.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDO07985.1 - 4e-14 52.2 0.0 5.3e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EDO07985.1 - 5.8e-13 48.5 0.0 6.4e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EDO07985.1 - 1.6e-12 46.8 1.6 2.2e-08 33.2 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDO07985.1 - 3.4e-10 39.4 0.0 4.2e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDO07985.1 - 3.5e-09 37.1 0.1 6.2e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDO07985.1 - 1.3e-05 25.0 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EDO07985.1 - 0.0024 17.0 0.1 0.0036 16.4 0.1 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EDO07985.1 - 0.011 15.6 0.4 0.034 14.0 0.2 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EDO07985.1 - 0.031 13.9 0.1 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 EDO07985.1 - 0.22 12.3 1.1 1 10.2 0.7 2.1 1 1 0 1 1 1 0 AAA domain HSP90 PF00183.13 EDO07986.1 - 1.6e-254 845.2 29.9 2.2e-254 844.8 20.7 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EDO07986.1 - 3.6e-12 46.0 0.5 3.6e-12 46.0 0.3 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDO07986.1 - 8.5e-11 41.5 0.1 1.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1510 PF07423.6 EDO07986.1 - 0.0028 17.0 15.2 0.0028 17.0 10.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) LOH1CR12 PF10158.4 EDO07986.1 - 0.019 14.7 0.5 0.057 13.2 0.1 1.9 2 0 0 2 2 2 0 Tumour suppressor protein SF3a60_bindingd PF12108.3 EDO07986.1 - 0.049 13.1 4.1 3.9 7.0 0.5 2.9 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain GAGA_bind PF06217.7 EDO07986.1 - 4.1 7.2 10.6 0.27 11.1 3.2 1.9 2 0 0 2 2 2 0 GAGA binding protein-like family DDHD PF02862.12 EDO07986.1 - 6.2 6.5 12.1 0.7 9.6 4.8 2.0 2 0 0 2 2 2 0 DDHD domain HSP70 PF00012.15 EDO07987.1 - 7.4e-81 271.8 0.0 1.4e-80 270.9 0.0 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EDO07987.1 - 9.2e-07 27.7 0.2 4.2e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein EMP24_GP25L PF01105.19 EDO07987.1 - 4.2 7.0 6.5 41 3.8 0.8 3.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD SCO1-SenC PF02630.9 EDO07988.1 - 2.5e-50 170.4 0.0 3.4e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EDO07988.1 - 1.1e-06 28.2 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EDO07988.1 - 0.0017 17.8 0.1 0.021 14.3 0.1 2.1 1 1 0 1 1 1 1 Redoxin Kdo PF06293.9 EDO07990.1 - 5.2e-14 51.7 0.1 7.9e-14 51.2 0.1 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EDO07990.1 - 7.6e-14 51.4 0.4 9.4e-14 51.1 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDO07990.1 - 9.4e-12 45.1 0.4 5.1e-05 23.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EDO07990.1 - 4.3e-11 42.4 0.2 6.2e-11 41.9 0.1 1.3 1 1 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EDO07990.1 - 8.2e-10 38.1 0.3 1e-09 37.8 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EDO07990.1 - 0.0002 20.9 0.1 0.0018 17.8 0.1 1.9 1 1 1 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.15 EDO07990.1 - 0.00055 19.1 0.0 0.00073 18.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase WaaY PF06176.6 EDO07990.1 - 0.007 15.6 1.2 0.0087 15.3 0.8 1.3 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH_6_hur PF04655.9 EDO07990.1 - 0.053 12.6 0.2 0.77 8.8 0.0 2.2 1 1 1 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase RNA_pol_N PF01194.12 EDO07992.1 - 4.1e-31 106.7 0.7 5.2e-31 106.4 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EDO07992.1 - 0.021 14.9 0.3 0.029 14.4 0.2 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Ribosomal_L37e PF01907.14 EDO07994.1 - 3.7e-24 84.2 11.3 6.7e-24 83.4 7.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EDO07994.1 - 0.0011 18.7 3.0 0.0021 17.8 2.1 1.5 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 EDO07994.1 - 0.069 12.8 0.3 0.092 12.4 0.2 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 EDO07994.1 - 0.42 10.3 5.5 0.23 11.2 2.2 1.7 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDO07994.1 - 0.46 10.2 3.6 0.77 9.4 1.4 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO07994.1 - 0.73 9.9 4.9 0.39 10.7 1.8 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GCV_H PF01597.14 EDO07995.1 - 0.00073 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein NOG1 PF06858.9 EDO07998.1 - 2.5e-26 91.3 0.2 5e-26 90.3 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EDO07998.1 - 2.4e-23 81.5 0.5 6e-23 80.2 0.3 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EDO07998.1 - 1.5e-15 57.1 0.0 3.7e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO07998.1 - 5.9e-10 38.6 0.0 1.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EDO07998.1 - 0.00051 20.5 0.1 0.0025 18.2 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EDO07998.1 - 0.017 14.9 1.4 7.6 6.3 0.0 3.3 3 1 1 4 4 4 0 Dynamin family AIG1 PF04548.11 EDO07998.1 - 0.024 13.7 0.0 0.05 12.7 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AAA_18 PF13238.1 EDO07998.1 - 0.047 13.9 0.1 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EDO07998.1 - 0.12 11.6 0.0 0.39 9.9 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EDO07998.1 - 0.17 11.4 0.0 8.1 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain LRR_4 PF12799.2 EDO07999.1 - 2.4e-10 39.7 9.2 0.00019 21.0 0.1 3.8 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDO07999.1 - 3.4e-06 26.7 5.0 0.0027 17.4 0.4 3.5 3 0 0 3 3 3 2 Leucine rich repeat ADIP PF11559.3 EDO08000.1 - 0.022 14.6 31.0 0.23 11.3 4.4 4.3 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding Sipho_Gp157 PF05565.6 EDO08000.1 - 0.032 13.8 21.8 0.96 9.0 3.7 3.7 3 1 0 3 3 3 0 Siphovirus Gp157 Reo_sigmaC PF04582.7 EDO08000.1 - 0.14 11.2 16.2 1.6 7.8 0.5 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF972 PF06156.8 EDO08000.1 - 0.76 10.1 24.7 0.26 11.6 5.1 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF972) FadA PF09403.5 EDO08000.1 - 0.86 9.6 22.3 0.028 14.4 4.8 3.4 2 1 2 4 4 4 0 Adhesion protein FadA Cep57_CLD_2 PF14197.1 EDO08000.1 - 1.3 9.0 25.8 0.44 10.5 1.7 5.0 3 2 2 5 5 5 0 Centrosome localisation domain of PPC89 Rootletin PF15035.1 EDO08000.1 - 1.5 8.7 26.5 0.53 10.2 5.9 3.2 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.10 EDO08000.1 - 2.8 7.5 27.7 0.28 10.7 3.3 4.8 3 1 1 4 4 4 0 Septum formation initiator IncA PF04156.9 EDO08000.1 - 3.3 7.2 37.5 13 5.3 6.2 3.3 1 1 1 2 2 2 0 IncA protein Mto2_bdg PF12808.2 EDO08000.1 - 4.4 7.4 12.0 5.3 7.2 0.9 2.8 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GNAT_acetyltr_2 PF13718.1 EDO08001.1 - 4.7e-65 218.5 0.0 7.7e-65 217.8 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EDO08001.1 - 4.1e-52 176.3 0.0 7.5e-52 175.5 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 EDO08001.1 - 5.5e-34 115.7 0.1 1.3e-33 114.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EDO08001.1 - 2.7e-20 72.3 0.1 9e-20 70.6 0.0 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain ATP-synt_DE_N PF02823.11 EDO08003.1 - 3.4e-15 55.5 0.2 4.7e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Ras PF00071.17 EDO08008.1 - 8.2e-58 194.3 0.2 1e-57 194.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO08008.1 - 3.6e-22 79.0 0.1 5.9e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO08008.1 - 6.6e-18 64.5 0.1 8.5e-18 64.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDO08008.1 - 1.9e-10 40.3 0.1 2.2e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO08008.1 - 4.1e-07 29.6 0.1 1.1e-05 24.9 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EDO08008.1 - 5.8e-07 28.8 0.1 9.3e-07 28.2 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EDO08008.1 - 4.1e-05 23.5 0.0 7.7e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO08008.1 - 0.00024 20.4 0.4 0.0066 15.7 0.3 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 EDO08008.1 - 0.064 12.9 0.1 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase Dynamin_N PF00350.18 EDO08008.1 - 0.086 12.6 0.1 1.1 9.0 0.0 2.4 2 1 1 3 3 3 0 Dynamin family ATP_bind_3 PF01171.15 EDO08009.1 - 8.2e-12 44.9 0.0 5.7e-10 38.9 0.0 2.4 2 1 0 2 2 2 1 PP-loop family PAPS_reduct PF01507.14 EDO08009.1 - 0.011 15.5 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family DUF2392 PF10288.4 EDO08009.1 - 0.013 15.8 0.1 0.035 14.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2392) Asn_synthase PF00733.16 EDO08009.1 - 0.055 12.9 0.1 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 Asparagine synthase ATP_bind_3 PF01171.15 EDO08011.1 - 9.4e-11 41.5 0.0 1.8e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 EDO08011.1 - 0.056 11.9 0.1 0.22 10.0 0.0 1.8 2 0 0 2 2 2 0 tRNA methyl transferase Asn_synthase PF00733.16 EDO08011.1 - 0.081 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase NAD_synthase PF02540.12 EDO08011.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 NAD synthase ATP_bind_3 PF01171.15 EDO08013.1 - 9.4e-11 41.5 0.0 1.8e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 EDO08013.1 - 0.056 11.9 0.1 0.22 10.0 0.0 1.8 2 0 0 2 2 2 0 tRNA methyl transferase Asn_synthase PF00733.16 EDO08013.1 - 0.081 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase NAD_synthase PF02540.12 EDO08013.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 NAD synthase COX2_TM PF02790.10 EDO08015.1 - 0.0042 17.0 0.0 0.0055 16.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain Methyltransf_18 PF12847.2 EDO08016.1 - 0.00038 21.0 0.0 0.001 19.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO08016.1 - 0.065 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 EDO08016.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase TTL PF03133.10 EDO08017.1 - 2.5e-43 148.0 0.0 4.2e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 EDO08017.1 - 2.2e-09 36.4 0.2 5e-07 28.7 0.0 2.8 2 1 1 3 3 3 2 YheC/D like ATP-grasp RimK PF08443.6 EDO08017.1 - 3e-05 23.5 0.0 0.29 10.5 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDO08017.1 - 0.00013 21.4 0.2 0.71 9.2 0.0 3.0 3 1 0 3 3 3 2 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 EDO08017.1 - 0.00037 20.2 0.0 0.0037 17.0 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain Plasmid_killer PF05015.8 EDO08017.1 - 0.0094 16.0 0.1 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 Plasmid maintenance system killer protein CPSase_L_D2 PF02786.12 EDO08017.1 - 0.044 13.0 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 EDO08017.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Prenyltrans PF00432.16 EDO08018.1 - 3.9e-35 119.0 13.7 5.3e-07 29.0 0.1 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDO08018.1 - 2.9e-16 59.8 0.0 1.6e-07 31.6 0.0 3.4 1 1 1 3 3 3 3 Prenyltransferase-like EF-hand_1 PF00036.27 EDO08019.1 - 8.8e-08 30.9 1.1 0.011 14.9 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 EDO08019.1 - 2.3e-07 29.8 0.6 0.0048 16.1 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EDO08019.1 - 2.2e-06 27.0 0.4 0.16 11.9 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EDO08019.1 - 1.3e-05 25.2 0.2 0.95 9.6 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 EDO08019.1 - 0.02 14.4 0.3 4.9 6.8 0.1 3.0 2 0 0 2 2 2 0 EF-hand domain pair PITH PF06201.8 EDO08020.1 - 1.3e-27 96.4 0.0 1.6e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain RRM_1 PF00076.17 EDO08022.1 - 8.6e-36 121.4 0.2 3.1e-17 61.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO08022.1 - 6.2e-30 102.9 0.0 1.1e-14 54.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO08022.1 - 4e-19 68.2 0.1 2.7e-08 33.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO08022.1 - 0.00028 20.5 0.1 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EDO08022.1 - 0.0079 16.0 1.3 0.17 11.7 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif MerC PF03203.9 EDO08023.1 - 3.4e-11 43.5 8.4 4.6e-11 43.1 5.8 1.1 1 0 0 1 1 1 1 MerC mercury resistance protein DUF2101 PF09874.4 EDO08023.1 - 0.054 12.9 3.6 0.068 12.6 2.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Ost4 PF10215.4 EDO08023.1 - 1.6 8.3 3.8 1.4 8.4 1.1 2.0 2 0 0 2 2 2 0 Oligosaccaryltransferase DUF2108 PF09881.4 EDO08023.1 - 2 8.2 10.1 0.16 11.7 3.3 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2108) DUF4491 PF14898.1 EDO08023.1 - 3.1 7.9 8.4 1.2 9.3 3.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4491) ATP-synt_C PF00137.16 EDO08025.1 - 6.3e-14 51.6 9.1 8.5e-14 51.2 6.3 1.2 1 0 0 1 1 1 1 ATP synthase subunit C Ribosomal_L18ae PF01775.12 EDO08026.1 - 1.8e-49 166.7 0.1 2.2e-49 166.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Ribosomal_L18e PF00828.14 EDO08027.1 - 2.6e-19 69.8 0.1 4e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 ATP-synt_D PF01813.12 EDO08028.1 - 1.4e-55 187.9 1.5 1.7e-55 187.6 1.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit D HALZ PF02183.13 EDO08028.1 - 0.059 13.0 2.2 0.068 12.9 0.1 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper HAUS2 PF15003.1 EDO08028.1 - 0.17 10.9 2.2 0.23 10.5 0.1 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 Ribosomal_S6e PF01092.14 EDO08029.1 - 1.4e-53 179.8 0.1 3.2e-53 178.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e CS PF04969.11 EDO08030.1 - 3e-07 30.8 0.0 4.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 CS domain RAP PF08373.5 EDO08031.1 - 6.6e-07 29.0 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 RAP domain Leo1 PF04004.8 EDO08032.1 - 2.4e-20 72.9 0.0 3.7e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Leo1-like protein SPG48 PF14764.1 EDO08033.1 - 0.08 11.4 0.0 0.086 11.3 0.0 1.0 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking E1-E2_ATPase PF00122.15 EDO08034.1 - 0.0027 16.7 1.5 0.0047 15.9 0.0 2.1 2 1 0 2 2 2 1 E1-E2 ATPase SF3b10 PF07189.6 EDO08035.1 - 6.3e-38 128.4 0.7 7.2e-38 128.2 0.5 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Med14 PF08638.6 EDO08036.1 - 3.3e-06 26.4 0.0 7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 TPR_16 PF13432.1 EDO08038.1 - 3.2e-29 100.9 8.0 0.00019 21.9 0.2 7.6 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 EDO08038.1 - 3.8e-25 86.0 14.4 0.00026 21.3 0.1 11.7 5 2 8 13 13 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 EDO08038.1 - 6.7e-23 80.8 0.1 5.2e-07 29.9 0.0 7.1 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDO08038.1 - 2.5e-17 61.2 11.8 0.0027 17.5 0.0 10.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_11 PF13414.1 EDO08038.1 - 1.9e-16 59.4 5.7 0.00017 21.1 0.0 7.3 6 2 2 8 8 8 3 TPR repeat HAT PF02184.11 EDO08038.1 - 2.2e-14 52.8 37.0 1.6e-05 24.5 0.0 9.2 12 0 0 12 12 9 4 HAT (Half-A-TPR) repeat Suf PF05843.9 EDO08038.1 - 1.3e-12 48.0 12.8 3.6e-06 26.9 1.1 7.1 2 2 3 5 5 5 2 Suppressor of forked protein (Suf) TPR_8 PF13181.1 EDO08038.1 - 2.1e-12 45.8 1.5 2.9 7.8 0.0 9.0 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDO08038.1 - 3.3e-12 46.1 13.3 7.9e-05 22.5 0.1 7.0 5 4 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDO08038.1 - 3.3e-10 39.3 2.5 0.0075 16.3 0.0 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO08038.1 - 3.8e-10 38.9 7.3 0.27 10.8 0.0 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDO08038.1 - 1.6e-07 30.5 12.5 0.31 10.9 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EDO08038.1 - 6.6e-06 25.2 11.7 0.061 12.2 0.1 5.2 3 3 1 4 4 4 3 NRDE-2, necessary for RNA interference Fis1_TPR_C PF14853.1 EDO08038.1 - 2e-05 24.3 0.3 1.8 8.5 0.0 5.6 7 0 0 7 7 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.1 EDO08038.1 - 2.6e-05 23.4 12.7 0.0079 15.2 1.3 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EDO08038.1 - 4.4e-05 23.5 3.1 0.51 10.5 0.1 4.5 4 1 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EDO08038.1 - 0.00013 21.7 2.0 1 9.2 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDO08038.1 - 0.00015 21.9 16.8 3.9 8.1 0.0 8.9 10 0 0 10 10 9 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EDO08038.1 - 0.00037 20.1 19.4 0.036 13.8 0.2 7.0 5 3 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_4 PF07721.9 EDO08038.1 - 0.21 12.1 9.9 1.4 9.5 0.0 5.4 7 0 0 7 7 4 0 Tetratricopeptide repeat DUF1625 PF07787.7 EDO08039.1 - 5.3e-53 179.8 0.0 7.7e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1625) DAGK_acc PF00609.14 EDO08039.1 - 9.8e-37 126.5 0.0 1.5e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EDO08039.1 - 1.5e-12 47.1 0.0 4.9e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain EpsG PF14897.1 EDO08039.1 - 0.0007 18.6 2.2 0.0012 17.8 1.5 1.2 1 0 0 1 1 1 1 EpsG family PHO4 PF01384.15 EDO08039.1 - 0.018 13.6 0.1 0.023 13.3 0.1 1.2 1 0 0 1 1 1 0 Phosphate transporter family TFIIF_alpha PF05793.7 EDO08040.1 - 0.12 10.7 3.8 0.15 10.4 2.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF566 PF04484.7 EDO08040.1 - 1.1 8.7 6.9 1.2 8.5 4.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Tmemb_cc2 PF10267.4 EDO08042.1 - 0.013 14.1 0.1 0.017 13.7 0.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Mnd1 PF03962.10 EDO08042.1 - 0.016 14.8 0.7 0.023 14.3 0.5 1.2 1 0 0 1 1 1 0 Mnd1 family HSCB_C PF07743.8 EDO08042.1 - 0.13 12.7 1.6 0.21 12.0 1.1 1.3 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain DNA_pol_E_B PF04042.11 EDO08043.1 - 5.8e-32 110.6 0.0 1.3e-31 109.4 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_topoisoIV PF00521.15 EDO08045.1 - 5.6e-126 420.8 0.0 9.4e-126 420.0 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EDO08045.1 - 4.3e-30 104.2 1.1 1.1e-29 102.8 0.7 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EDO08045.1 - 2.5e-12 46.6 0.0 7.1e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Seryl_tRNA_N PF02403.17 EDO08046.1 - 0.001 19.0 6.7 0.001 19.0 4.7 2.4 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain EzrA PF06160.7 EDO08046.1 - 0.0011 17.3 10.9 0.0017 16.6 7.6 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA GAS PF13851.1 EDO08046.1 - 0.0022 17.2 6.3 0.0022 17.2 4.3 2.2 1 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EDO08046.1 - 0.0083 16.4 12.1 0.33 11.3 1.3 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF972) ATG16 PF08614.6 EDO08046.1 - 0.011 15.5 13.2 0.02 14.7 9.2 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 EDO08046.1 - 0.031 14.1 17.3 1.8 8.4 10.8 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.1 EDO08046.1 - 0.14 12.2 10.5 0.049 13.7 3.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Laminin_II PF06009.7 EDO08046.1 - 0.21 11.3 9.1 0.45 10.2 2.1 2.4 1 1 1 2 2 2 0 Laminin Domain II FlaC_arch PF05377.6 EDO08046.1 - 0.33 10.8 7.0 5.6 6.9 0.4 3.2 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 EDO08046.1 - 0.36 9.8 15.4 0.94 8.4 9.7 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF904 PF06005.7 EDO08046.1 - 0.36 11.1 17.6 0.13 12.5 2.5 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF904) DUF3166 PF11365.3 EDO08046.1 - 0.41 11.1 4.9 14 6.1 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) DUF724 PF05266.9 EDO08046.1 - 0.43 10.1 6.7 2.3 7.8 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4140 PF13600.1 EDO08046.1 - 0.46 10.9 11.1 3.1 8.2 0.2 3.2 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.7 EDO08046.1 - 0.47 10.2 8.3 0.086 12.6 1.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Nsp1_C PF05064.8 EDO08046.1 - 0.48 10.0 8.8 0.65 9.6 4.3 2.5 2 1 1 3 3 2 0 Nsp1-like C-terminal region Baculo_PEP_C PF04513.7 EDO08046.1 - 0.54 10.0 6.4 0.74 9.6 1.2 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 EDO08046.1 - 1.1 7.0 10.5 1.5 6.5 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med4 PF10018.4 EDO08046.1 - 1.2 8.4 13.0 0.024 14.0 2.6 2.2 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 IncA PF04156.9 EDO08046.1 - 1.6 8.2 18.2 7.3 6.1 12.6 1.9 1 1 0 1 1 1 0 IncA protein CENP-H PF05837.7 EDO08046.1 - 1.6 8.9 11.9 1 9.5 1.7 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Occludin_ELL PF07303.8 EDO08046.1 - 1.9 9.2 7.6 0.74 10.5 2.7 2.2 1 1 1 2 2 2 0 Occludin homology domain DivIC PF04977.10 EDO08046.1 - 2.1 7.8 14.7 0.48 9.9 0.7 3.9 3 1 1 4 4 4 0 Septum formation initiator DUF4200 PF13863.1 EDO08046.1 - 2.6 7.9 14.7 1.4 8.8 5.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 EDO08046.1 - 5.6 6.7 13.4 38 4.0 9.1 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FHA PF00498.21 EDO08047.1 - 4.1e-17 62.0 0.1 8.7e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 FHA domain FYTT PF07078.6 EDO08047.1 - 0.063 12.5 0.0 4.4 6.5 0.0 2.1 2 0 0 2 2 2 0 Forty-two-three protein AAA_23 PF13476.1 EDO08047.1 - 0.11 12.8 9.5 0.15 12.3 6.6 1.2 1 0 0 1 1 1 0 AAA domain DUF2968 PF11180.3 EDO08047.1 - 2.3 7.5 9.8 0.22 10.8 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Tubulin PF00091.20 EDO08048.1 - 3.1e-72 242.9 0.0 4.9e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDO08048.1 - 4.1e-48 162.5 0.3 6.4e-48 161.9 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EDO08048.1 - 1.5e-05 24.9 0.0 3.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EDO08048.1 - 0.0035 16.8 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Rcd1 PF04078.8 EDO08049.1 - 1.3e-106 355.2 0.3 1.6e-106 354.9 0.2 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Pkinase PF00069.20 EDO08050.1 - 7.8e-12 44.8 0.0 1.3e-11 44.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain EppA_BapA PF07268.6 EDO08051.1 - 0.0038 16.9 0.2 0.01 15.5 0.1 1.7 1 0 0 1 1 1 1 Exported protein precursor (EppA/BapA) Apolipo_F PF15148.1 EDO08051.1 - 0.016 14.5 0.5 0.082 12.2 0.1 2.1 1 1 0 2 2 2 0 Apolipoprotein F DUF1073 PF06381.6 EDO08051.1 - 0.016 13.6 3.0 0.035 12.5 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1073) Syntaxin-6_N PF09177.6 EDO08051.1 - 3.2 8.2 7.5 45 4.5 0.4 4.2 3 2 1 4 4 4 0 Syntaxin 6, N-terminal ABC_tran PF00005.22 EDO08053.1 - 2.6e-37 128.1 0.0 5.4e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EDO08053.1 - 1.1e-14 54.5 11.0 1.4e-14 54.1 7.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EDO08053.1 - 2e-08 33.7 0.0 2e-05 23.9 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDO08053.1 - 1.5e-07 31.6 0.1 4.2e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO08053.1 - 3.6e-05 23.9 0.1 0.00073 19.6 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_29 PF13555.1 EDO08053.1 - 0.00034 20.0 0.1 0.00082 18.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_membrane_2 PF06472.10 EDO08053.1 - 0.00065 18.9 1.9 0.0012 18.0 1.3 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 AAA_16 PF13191.1 EDO08053.1 - 0.00076 19.5 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EDO08053.1 - 0.0016 17.6 0.1 0.0031 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EDO08053.1 - 0.0026 17.2 0.2 0.021 14.2 0.0 2.4 3 0 0 3 3 3 1 AAA-like domain Gtr1_RagA PF04670.7 EDO08053.1 - 0.003 16.7 0.3 0.041 13.0 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_17 PF13207.1 EDO08053.1 - 0.0037 18.0 0.0 0.011 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 EDO08053.1 - 0.0068 15.9 0.1 0.016 14.7 0.1 1.6 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EDO08053.1 - 0.0084 16.4 0.0 0.024 14.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EDO08053.1 - 0.0088 15.1 0.0 0.028 13.4 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.15 EDO08053.1 - 0.0097 15.5 0.9 0.028 14.0 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_23 PF13476.1 EDO08053.1 - 0.011 16.0 0.1 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EDO08053.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF87 PF01935.12 EDO08053.1 - 0.013 15.3 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_14 PF13173.1 EDO08053.1 - 0.014 15.2 0.3 0.12 12.3 0.0 2.4 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.1 EDO08053.1 - 0.017 14.9 0.4 0.24 11.3 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EDO08053.1 - 0.023 14.9 0.0 0.16 12.1 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EDO08053.1 - 0.028 14.1 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EDO08053.1 - 0.033 13.8 0.0 0.088 12.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EDO08053.1 - 0.035 12.9 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DEAD PF00270.24 EDO08053.1 - 0.046 13.2 0.1 0.13 11.7 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase G-alpha PF00503.15 EDO08053.1 - 0.068 11.8 0.0 0.086 11.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF815 PF05673.8 EDO08053.1 - 0.069 12.0 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Miro PF08477.8 EDO08053.1 - 0.078 13.4 0.1 0.22 12.0 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein AAA_30 PF13604.1 EDO08053.1 - 0.079 12.5 0.0 0.23 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDO08053.1 - 0.092 12.4 0.0 1.7 8.3 0.0 2.7 2 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EDO08053.1 - 0.095 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain UCH_1 PF13423.1 EDO08054.1 - 1.6e-07 31.0 2.2 1.6e-07 31.0 1.5 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EDO08055.1 - 2.4e-19 70.2 0.0 4.4e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Exonuclease Oleosin PF01277.12 EDO08056.1 - 4.4 6.8 7.0 11 5.5 0.5 3.0 2 2 0 2 2 2 0 Oleosin Ubiq_cyt_C_chap PF03981.7 EDO08059.1 - 4.9e-24 84.7 0.1 7.2e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone YxiJ PF14176.1 EDO08059.1 - 0.018 15.1 0.4 0.049 13.7 0.2 1.7 1 0 0 1 1 1 0 YxiJ-like protein GTP1_OBG PF01018.17 EDO08060.1 - 3.5e-16 59.2 0.3 5.3e-16 58.6 0.2 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 EDO08060.1 - 1.9e-13 50.4 0.0 3.1e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO08060.1 - 1.7e-08 33.8 0.0 3.3e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EDO08060.1 - 8.3e-06 25.3 0.0 0.016 14.6 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDO08060.1 - 0.00036 19.7 0.0 0.0005 19.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDO08060.1 - 0.033 14.6 0.0 0.095 13.2 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein Ras PF00071.17 EDO08060.1 - 0.046 13.1 0.0 9 5.6 0.0 2.1 2 0 0 2 2 2 0 Ras family MobB PF03205.9 EDO08060.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 EDO08060.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Tubulin PF00091.20 EDO08061.1 - 1.5e-25 90.2 0.2 4e-25 88.9 0.1 1.8 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DUF2036 PF09724.4 EDO08062.1 - 0.0043 16.2 3.1 0.76 8.8 0.0 3.2 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2036) Ctf8 PF09696.5 EDO08062.1 - 0.017 14.8 0.0 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 Ctf8 WD40 PF00400.27 EDO08063.1 - 1.5e-06 27.8 11.2 0.087 12.7 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 EDO08063.1 - 5.4e-06 25.6 0.2 2.5e-05 23.5 0.0 2.0 2 1 1 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus CDT1 PF08839.6 EDO08064.1 - 1.2e-21 77.3 0.0 2.1e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like CDT1 PF08839.6 EDO08067.1 - 1.2e-21 77.3 0.0 2.1e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like LisH PF08513.6 EDO08068.1 - 1.3e-11 43.8 0.2 2.8e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 LisH WD40 PF00400.27 EDO08068.1 - 3.1e-06 26.8 11.2 0.1 12.5 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 EDO08068.1 - 7.1e-06 25.2 0.2 3.1e-05 23.1 0.0 2.0 2 1 1 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3223 PF11523.3 EDO08069.1 - 2.9e-21 75.5 0.2 1e-20 73.7 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3223) La PF05383.12 EDO08069.1 - 3.9e-05 23.3 0.1 0.00011 21.9 0.0 1.8 2 0 0 2 2 2 1 La domain Reoviridae_Vp9 PF08978.5 EDO08070.1 - 0.092 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Reoviridae VP9 Y_Y_Y PF07495.8 EDO08070.1 - 0.39 10.5 2.0 14 5.5 0.3 3.2 3 0 0 3 3 3 0 Y_Y_Y domain zf-DHHC PF01529.15 EDO08071.1 - 2.8e-38 131.0 10.5 2.8e-38 131.0 7.3 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 EDO08071.1 - 4.9 7.0 7.6 10 6.0 5.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon ATP-synt_F PF01990.12 EDO08072.1 - 2.9e-30 104.4 0.8 3.6e-30 104.2 0.6 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF2972 PF11186.3 EDO08072.1 - 0.019 14.8 0.1 0.019 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) ATP_bind_4 PF01902.12 EDO08073.1 - 1.3e-46 158.7 0.1 3.2e-46 157.4 0.1 1.6 1 1 0 1 1 1 1 ATP-binding region QueC PF06508.8 EDO08073.1 - 3.5e-05 23.2 0.0 4.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EDO08073.1 - 0.0027 16.3 0.0 0.0047 15.5 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase Rep_fac-A_C PF08646.5 EDO08074.1 - 5.8e-26 90.9 1.2 5.8e-26 90.9 0.8 2.6 2 1 0 3 3 3 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 EDO08074.1 - 7.6e-08 32.1 0.3 2.3e-06 27.3 0.0 3.3 4 0 0 4 4 4 1 OB-fold nucleic acid binding domain SSB PF00436.20 EDO08074.1 - 0.0074 16.1 2.9 0.37 10.6 0.0 3.4 3 1 1 4 4 4 1 Single-strand binding protein family DUF223 PF02721.9 EDO08074.1 - 0.014 15.4 0.4 0.047 13.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF223 Ribosomal_S27 PF01599.14 EDO08074.1 - 0.021 14.6 1.3 0.045 13.5 0.2 2.1 2 0 0 2 2 2 0 Ribosomal protein S27a Brix PF04427.13 EDO08076.1 - 6.4e-45 153.1 0.0 8.3e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Brix domain PNP_UDP_1 PF01048.15 EDO08077.1 - 3.8e-22 78.4 0.0 4.5e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.15 EDO08078.1 - 8.9e-10 37.9 0.0 1e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Mito_carr PF00153.22 EDO08079.1 - 1.3e-55 185.1 1.5 1.5e-19 69.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein eIF2A PF08662.6 EDO08080.1 - 1.8e-52 177.9 0.3 3.8e-51 173.5 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A tRNA-synt_His PF13393.1 EDO08081.1 - 6.8e-30 104.1 0.0 1.1e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EDO08081.1 - 9.5e-06 25.2 0.0 0.00028 20.4 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) CS PF04969.11 EDO08082.1 - 0.0019 18.6 0.0 0.0034 17.8 0.0 1.4 1 0 0 1 1 1 1 CS domain ThiF PF00899.16 EDO08083.1 - 1.7e-36 124.9 0.8 3.7e-36 123.9 0.5 1.5 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 EDO08083.1 - 0.0069 15.4 2.0 0.034 13.1 1.4 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase MoeZ_MoeB PF05237.8 EDO08083.1 - 0.018 14.5 0.0 0.047 13.2 0.0 1.7 1 0 0 1 1 1 0 MoeZ/MoeB domain NAD_binding_7 PF13241.1 EDO08083.1 - 0.021 15.0 0.1 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 EDO08083.1 - 0.026 13.6 0.1 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EDO08083.1 - 0.066 12.2 1.3 0.11 11.5 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 EDO08083.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DEAD PF00270.24 EDO08085.1 - 5.3e-37 126.9 0.1 9e-37 126.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO08085.1 - 1.8e-19 69.3 0.0 9.5e-18 63.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EDO08085.1 - 8.1e-18 63.7 0.1 2e-17 62.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DUF3658 PF12395.3 EDO08085.1 - 0.04 13.4 2.3 0.092 12.3 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function Arteri_nucleo PF01481.11 EDO08085.1 - 0.08 13.0 0.0 0.58 10.2 0.0 2.4 2 0 0 2 2 2 0 Arterivirus nucleocapsid protein ResIII PF04851.10 EDO08085.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Peptidase_M41 PF01434.13 EDO08086.1 - 8.8e-64 214.8 0.0 1.3e-63 214.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EDO08086.1 - 5.7e-41 139.8 0.0 1e-40 138.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EDO08086.1 - 9.8e-07 28.9 0.0 3.4e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 EDO08086.1 - 7e-05 23.6 0.0 0.00019 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO08086.1 - 0.00046 20.3 0.1 0.016 15.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EDO08086.1 - 0.002 16.9 0.0 0.0032 16.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EDO08086.1 - 0.0024 17.6 0.0 0.0077 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EDO08086.1 - 0.013 14.5 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EDO08086.1 - 0.024 13.7 0.0 0.057 12.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EDO08086.1 - 0.031 14.1 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EDO08086.1 - 0.036 13.4 0.1 0.075 12.4 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.9 EDO08086.1 - 0.046 13.6 0.0 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EDO08086.1 - 0.052 13.2 1.2 0.12 12.1 0.2 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 EDO08086.1 - 0.059 13.3 0.1 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EDO08086.1 - 0.067 12.3 0.3 0.32 10.1 0.1 2.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EDO08086.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EDO08086.1 - 0.083 12.8 0.1 0.39 10.6 0.1 1.9 1 1 1 2 2 2 0 AAA ATPase domain Peptidase_M50B PF13398.1 EDO08086.1 - 0.17 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase M50B-like AAA_25 PF13481.1 EDO08086.1 - 0.27 10.6 1.3 0.75 9.1 0.4 2.0 1 1 1 2 2 2 0 AAA domain SUI1 PF01253.17 EDO08087.1 - 2.1e-17 62.6 0.1 3.2e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GTP_EFTU_D2 PF03144.20 EDO08087.1 - 0.11 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Elongation factor Tu domain 2 SRP54 PF00448.17 EDO08091.1 - 5.9e-54 182.4 0.2 2.7e-53 180.3 0.1 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EDO08091.1 - 8.6e-15 54.8 9.0 1.4e-11 44.2 0.5 2.3 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 EDO08091.1 - 7e-07 28.8 0.4 2.7e-06 26.9 0.3 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EDO08091.1 - 5.2e-05 22.1 0.0 0.00028 19.7 0.0 2.2 1 1 1 2 2 2 1 ArgK protein AAA_16 PF13191.1 EDO08091.1 - 0.00034 20.6 0.2 0.0013 18.7 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain SRP54_N PF02881.14 EDO08091.1 - 0.0005 20.1 0.2 0.0005 20.1 0.2 3.2 4 0 0 4 4 4 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.1 EDO08091.1 - 0.0018 17.8 0.0 0.0047 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO08091.1 - 0.0059 16.7 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EDO08091.1 - 0.0061 16.2 0.1 0.37 10.4 0.1 3.2 2 1 1 3 3 3 1 NTPase AAA_29 PF13555.1 EDO08091.1 - 0.0085 15.5 0.1 0.052 13.0 0.1 2.3 1 1 1 2 2 2 1 P-loop containing region of AAA domain APS_kinase PF01583.15 EDO08091.1 - 0.042 13.5 0.4 0.77 9.4 0.0 2.7 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_10 PF12846.2 EDO08091.1 - 0.044 13.2 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain Fer4_NifH PF00142.13 EDO08091.1 - 0.052 12.7 0.1 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ABC_tran PF00005.22 EDO08091.1 - 0.086 13.1 0.5 1 9.6 0.0 2.5 2 0 0 2 2 2 0 ABC transporter NDK PF00334.14 EDO08092.1 - 4.6e-50 168.9 0.0 5.2e-50 168.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase TadE PF07811.7 EDO08092.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 TadE-like protein DUF501 PF04417.7 EDO08093.1 - 2e-14 53.6 0.0 6.1e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF501) zf-Tim10_DDP PF02953.10 EDO08094.1 - 0.037 13.3 1.0 0.25 10.6 0.0 2.7 3 0 0 3 3 3 0 Tim10/DDP family zinc finger Clat_adaptor_s PF01217.15 EDO08095.1 - 4.3e-35 120.5 1.2 4.6e-35 120.4 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fe-S_assembly PF04384.8 EDO08095.1 - 0.16 12.3 0.5 16 5.9 0.0 2.6 2 1 1 3 3 3 0 Iron-sulphur cluster assembly DUF2953 PF11167.3 EDO08096.1 - 0.5 10.3 3.4 1.1 9.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) DnaJ PF00226.26 EDO08097.1 - 6.1e-13 48.2 1.3 1e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 EDO08097.1 - 4e-05 23.1 3.8 0.0015 18.1 0.1 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EDO08097.1 - 0.0044 16.5 0.5 0.044 13.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat V_ATPase_I PF01496.14 EDO08097.1 - 0.069 10.9 2.5 0.15 9.9 1.7 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CTNNBL PF08216.6 EDO08098.1 - 1.1e-22 79.6 0.0 3.6e-22 78.0 0.0 1.9 1 1 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear ParcG PF10274.4 EDO08098.1 - 0.043 13.7 0.4 0.24 11.2 0.2 2.1 1 1 1 2 2 2 0 Parkin co-regulated protein DUF1098 PF06497.6 EDO08098.1 - 0.074 13.1 5.0 0.69 10.0 0.2 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1098) Carb_anhydrase PF00194.16 EDO08099.1 - 4.8e-11 42.1 0.1 4.8e-11 42.1 0.0 2.9 3 1 0 3 3 3 2 Eukaryotic-type carbonic anhydrase WD40 PF00400.27 EDO08101.1 - 4.3e-34 115.1 10.7 7.2e-09 35.1 1.2 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EDO08101.1 - 0.00027 20.5 0.1 0.0039 16.6 0.0 2.5 3 0 0 3 3 3 1 PQQ-like domain eIF2A PF08662.6 EDO08101.1 - 0.018 14.7 0.1 2.2 7.9 0.0 2.9 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF367 PF04034.8 EDO08102.1 - 5.6e-41 139.1 0.0 7.8e-41 138.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EDO08102.1 - 5.4e-13 48.2 0.2 8.8e-13 47.6 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Glyco_trans_1_4 PF13692.1 EDO08102.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 CwfJ_C_1 PF04677.10 EDO08103.1 - 5.9e-17 61.4 0.1 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EDO08103.1 - 2.8e-12 46.9 0.0 5.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF3369 PF11849.3 EDO08103.1 - 0.013 15.4 0.3 0.024 14.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) IQ PF00612.22 EDO08104.1 - 1.3e-11 43.0 41.3 2.5e-05 23.5 1.3 7.1 7 0 0 7 7 7 4 IQ calmodulin-binding motif RCC1 PF00415.13 EDO08104.1 - 3.1e-11 43.2 10.5 1e-07 32.0 1.5 4.9 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDO08104.1 - 1.3e-09 37.4 5.8 1.6e-07 30.7 0.0 3.9 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat TPR_11 PF13414.1 EDO08105.1 - 2.6e-15 55.8 8.5 1.3e-11 43.9 1.1 3.1 2 1 1 3 3 3 2 TPR repeat Aha1_N PF09229.6 EDO08105.1 - 2.5e-13 50.0 1.4 4.1e-13 49.3 0.1 2.1 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal TPR_2 PF07719.12 EDO08105.1 - 1.1e-06 28.0 6.9 0.47 10.4 0.4 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat DUF3856 PF12968.2 EDO08105.1 - 4.4e-06 26.5 0.3 1.5e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.1 EDO08105.1 - 0.00011 22.5 2.9 0.0026 18.0 0.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO08105.1 - 0.00082 19.9 5.5 0.0054 17.3 0.5 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDO08105.1 - 0.00094 18.6 10.4 0.3 10.7 0.2 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDO08105.1 - 0.002 18.6 0.3 0.057 14.0 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDO08105.1 - 0.0073 16.1 0.9 0.1 12.5 0.2 2.7 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat DUF3281 PF11685.3 EDO08105.1 - 0.0075 15.4 1.4 0.98 8.5 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3281) TPR_9 PF13371.1 EDO08105.1 - 0.0087 15.8 0.4 0.021 14.6 0.3 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDO08105.1 - 0.036 13.9 0.9 0.094 12.6 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDO08105.1 - 0.18 12.0 2.7 17 5.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 EDO08106.1 - 6.9e-06 26.0 0.1 1.8e-05 24.6 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO08106.1 - 0.0013 18.7 0.1 0.0035 17.4 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDO08106.1 - 0.016 15.3 0.1 0.095 12.8 0.1 2.2 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EDO08106.1 - 0.089 12.6 0.6 0.8 9.6 0.1 2.2 1 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain AAA_16 PF13191.1 EDO08107.1 - 1.3e-08 35.1 0.0 1e-07 32.1 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EDO08107.1 - 3.4e-07 30.2 0.1 4.9e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EDO08107.1 - 3.4e-06 26.8 0.1 5.3e-05 22.9 0.0 2.6 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EDO08107.1 - 8.8e-06 25.8 0.1 1.9e-05 24.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO08107.1 - 1.2e-05 24.9 0.0 7.6e-05 22.3 0.0 2.3 3 0 0 3 3 2 1 Part of AAA domain DUF2075 PF09848.4 EDO08107.1 - 0.00012 21.1 0.0 0.00021 20.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EDO08107.1 - 0.00023 21.9 0.1 0.00072 20.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EDO08107.1 - 0.00042 20.5 0.1 0.0016 18.6 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EDO08107.1 - 0.001 18.0 0.0 0.0023 16.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.1 EDO08107.1 - 0.0012 18.7 0.5 0.011 15.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 EDO08107.1 - 0.0016 18.1 0.3 0.0038 16.9 0.2 1.8 1 1 0 1 1 1 1 NTPase NB-ARC PF00931.17 EDO08107.1 - 0.0025 16.7 0.1 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RNA12 PF10443.4 EDO08107.1 - 0.003 16.1 0.0 0.0051 15.3 0.0 1.3 1 0 0 1 1 1 1 RNA12 protein Viral_helicase1 PF01443.13 EDO08107.1 - 0.0041 16.6 0.0 0.009 15.5 0.0 1.6 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase KTI12 PF08433.5 EDO08107.1 - 0.0099 15.1 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EDO08107.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EDO08107.1 - 0.017 15.4 0.3 0.052 13.8 0.2 2.0 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 EDO08107.1 - 0.023 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Sigma54_activ_2 PF14532.1 EDO08107.1 - 0.026 14.5 0.0 0.08 12.9 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 EDO08107.1 - 0.028 13.8 0.1 0.096 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.4 EDO08107.1 - 0.032 13.1 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 cobW PF02492.14 EDO08107.1 - 0.034 13.5 0.0 0.061 12.7 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.1 EDO08107.1 - 0.039 13.5 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EDO08107.1 - 0.049 12.5 0.0 0.089 11.6 0.0 1.5 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain LRR_adjacent PF08191.6 EDO08107.1 - 0.049 13.3 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 LRR adjacent IstB_IS21 PF01695.12 EDO08107.1 - 0.055 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zot PF05707.7 EDO08107.1 - 0.063 12.7 0.1 0.62 9.4 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) ResIII PF04851.10 EDO08107.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EDO08107.1 - 0.065 12.5 0.2 0.14 11.4 0.1 1.7 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain PhoH PF02562.11 EDO08107.1 - 0.072 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 EDO08107.1 - 0.08 12.8 0.1 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EDO08107.1 - 0.091 11.7 0.1 0.37 9.7 0.0 1.7 1 1 0 2 2 2 0 KAP family P-loop domain ArgK PF03308.11 EDO08107.1 - 0.092 11.5 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 ArgK protein RNA_helicase PF00910.17 EDO08107.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF1796 PF08795.5 EDO08107.1 - 0.14 11.7 0.5 0.45 10.1 0.2 1.6 1 1 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) Oxysterol_BP PF01237.13 EDO08108.1 - 1.9e-130 434.5 0.0 2.5e-130 434.1 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein DUF1965 PF09248.5 EDO08109.1 - 0.028 14.3 0.2 0.046 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Pkinase PF00069.20 EDO08110.1 - 1.5e-74 250.4 0.2 2.3e-74 249.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO08110.1 - 4.6e-37 127.4 0.1 7e-37 126.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 EDO08110.1 - 9e-18 64.1 0.2 9.8e-11 41.6 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EDO08110.1 - 2.1e-17 61.0 1.7 8.9e-06 24.6 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EDO08110.1 - 2e-14 52.9 3.5 1.3e-06 27.9 0.5 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EDO08110.1 - 3.8e-13 48.1 1.2 0.0049 16.6 0.0 4.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EDO08110.1 - 8.2e-10 37.5 3.2 0.022 14.0 0.0 4.0 4 0 0 4 4 4 3 EF hand APH PF01636.18 EDO08110.1 - 4.1e-05 23.4 0.0 0.00072 19.3 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EDO08110.1 - 0.0047 16.3 0.1 0.022 14.1 0.0 2.0 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EDO08110.1 - 0.0058 15.7 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EDO08110.1 - 0.024 14.2 0.0 0.11 12.0 0.0 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase EF-hand_9 PF14658.1 EDO08110.1 - 0.089 12.7 0.7 2.3 8.2 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain YdjO PF14169.1 EDO08110.1 - 0.21 11.0 6.5 0.38 10.2 1.8 2.4 2 0 0 2 2 2 0 Cold-inducible protein YdjO UBA PF00627.26 EDO08111.1 - 9.1e-05 22.1 0.1 0.00022 20.9 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 EDO08111.1 - 0.002 17.5 0.0 0.0051 16.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Nitr_red_assoc PF09655.5 EDO08111.1 - 0.14 12.4 0.3 0.25 11.6 0.2 1.3 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) PseudoU_synth_1 PF01416.15 EDO08112.1 - 5.3e-32 110.3 0.0 1.6e-15 57.3 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.4 EDO08112.1 - 0.0007 19.1 0.0 0.00097 18.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) Requiem_N PF14051.1 EDO08112.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. Glyco_hydro_35 PF01301.14 EDO08114.1 - 0.046 13.0 0.4 0.066 12.5 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Cytochrom_C PF00034.16 EDO08115.1 - 1.1e-13 51.7 0.1 1.7e-13 51.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EDO08115.1 - 6.7e-07 29.3 2.5 2.2e-06 27.7 1.7 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EDO08115.1 - 8.6e-05 22.0 0.1 0.00018 20.9 0.1 1.5 1 0 0 1 1 1 1 Cytochrome c-550 domain Haem_bd PF14376.1 EDO08115.1 - 0.033 13.8 0.3 0.053 13.2 0.0 1.4 2 0 0 2 2 2 0 Haem-binding domain Cytochrom_C1 PF02167.10 EDO08115.1 - 0.036 13.7 0.0 0.068 12.8 0.0 1.4 2 0 0 2 2 2 0 Cytochrome C1 family DUF1111 PF06537.6 EDO08115.1 - 0.14 10.4 0.4 0.24 9.6 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1111) TMC PF07810.8 EDO08116.1 - 0.19 12.1 4.6 0.11 12.8 1.1 2.2 2 1 0 2 2 2 0 TMC domain DUF2809 PF10990.3 EDO08116.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2809) Sec62 PF03839.11 EDO08118.1 - 4.7e-21 75.2 7.8 8.1e-21 74.4 5.4 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 Ribosomal_L20 PF00453.13 EDO08119.1 - 5.3e-29 100.3 1.5 6.3e-29 100.0 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 HTH_1 PF00126.22 EDO08119.1 - 0.057 13.1 0.1 0.27 11.0 0.0 2.0 2 1 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family ABC_tran PF00005.22 EDO08120.1 - 3.5e-32 111.5 0.0 4.9e-15 56.0 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDO08120.1 - 4.5e-10 39.9 0.7 0.025 14.5 0.0 4.6 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EDO08120.1 - 6.7e-07 29.8 1.7 0.0069 16.7 0.2 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EDO08120.1 - 1.1e-06 27.9 0.2 0.0018 17.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDO08120.1 - 5e-06 26.6 0.0 0.037 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EDO08120.1 - 8.3e-06 25.2 0.3 0.15 11.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 EDO08120.1 - 2.1e-05 24.3 0.0 0.00016 21.5 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EDO08120.1 - 5.8e-05 22.7 0.2 0.043 13.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EDO08120.1 - 8.9e-05 23.2 0.0 0.71 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EDO08120.1 - 9.8e-05 21.5 0.1 0.1 11.6 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin UPF0079 PF02367.12 EDO08120.1 - 0.00015 21.3 0.6 0.046 13.3 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 EDO08120.1 - 0.00016 21.6 0.2 0.15 12.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EDO08120.1 - 0.00018 21.8 0.1 1 9.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 EDO08120.1 - 0.00026 20.7 0.3 0.013 15.1 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EDO08120.1 - 0.00027 21.0 0.1 0.72 9.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EDO08120.1 - 0.00027 20.7 0.5 0.042 13.5 0.0 2.7 3 0 0 3 3 2 1 Archaeal ATPase NACHT PF05729.7 EDO08120.1 - 0.00028 20.5 0.5 0.8 9.3 0.1 2.6 2 0 0 2 2 2 2 NACHT domain ArgK PF03308.11 EDO08120.1 - 0.00039 19.3 0.6 0.016 14.0 0.1 2.2 2 0 0 2 2 2 1 ArgK protein NB-ARC PF00931.17 EDO08120.1 - 0.00096 18.0 0.8 0.049 12.4 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain AAA_25 PF13481.1 EDO08120.1 - 0.0011 18.4 0.0 1.7 7.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EDO08120.1 - 0.0012 19.3 0.2 0.42 11.1 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 EDO08120.1 - 0.0043 16.0 0.1 1.7 7.5 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein PduV-EutP PF10662.4 EDO08120.1 - 0.01 15.2 2.3 1.7 8.1 0.0 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EDO08120.1 - 0.024 14.8 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EDO08120.1 - 0.032 14.0 0.6 0.24 11.2 0.1 2.2 2 0 0 2 2 2 0 Dynamin family SMC_N PF02463.14 EDO08120.1 - 0.035 13.3 0.5 0.77 8.9 0.1 2.5 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain KAP_NTPase PF07693.9 EDO08120.1 - 0.053 12.5 0.0 3.3 6.6 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain cobW PF02492.14 EDO08120.1 - 0.053 12.9 0.5 0.74 9.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EDO08120.1 - 0.054 13.4 2.9 21 5.0 0.1 3.6 4 0 0 4 4 3 0 AAA domain AAA_10 PF12846.2 EDO08120.1 - 0.058 12.8 0.1 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_15 PF13175.1 EDO08120.1 - 0.08 11.9 0.0 2.1 7.2 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain DUF815 PF05673.8 EDO08120.1 - 0.086 11.7 0.3 0.49 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PRK PF00485.13 EDO08120.1 - 0.098 12.1 0.2 4.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.1 EDO08120.1 - 0.16 11.7 1.1 23 4.8 0.0 2.8 3 0 0 3 3 2 0 Part of AAA domain ABC_ATPase PF09818.4 EDO08120.1 - 0.3 9.6 0.1 11 4.4 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class CorA PF01544.13 EDO08123.1 - 0.09 11.7 2.7 0.38 9.7 1.7 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF1411 PF07199.6 EDO08123.1 - 0.18 11.1 0.1 0.18 11.1 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1411) Suf PF05843.9 EDO08123.1 - 5.3 6.6 17.0 8.1 6.0 11.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 EDO08123.1 - 6.6 4.2 21.1 7.7 4.0 14.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2201_N PF13203.1 EDO08123.1 - 7.2 5.6 23.1 12 4.9 16.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1411 PF07199.6 EDO08126.1 - 0.0019 17.6 0.1 0.0064 15.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1411) DUF1411 PF07199.6 EDO08127.1 - 0.0048 16.3 0.0 0.15 11.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1411) DUF1411 PF07199.6 EDO08128.1 - 0.097 12.1 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1411) YCII PF03795.9 EDO08130.1 - 0.0054 16.8 0.0 0.071 13.3 0.0 2.3 2 0 0 2 2 2 1 YCII-related domain DUF1408 PF07193.6 EDO08130.1 - 0.092 12.2 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) WD40 PF00400.27 EDO08131.1 - 9e-06 25.3 10.2 2.7 8.0 0.0 7.7 7 1 0 7 7 7 3 WD domain, G-beta repeat HSP90 PF00183.13 EDO08131.1 - 0.13 10.6 0.8 0.2 10.0 0.6 1.1 1 0 0 1 1 1 0 Hsp90 protein LSM14 PF12701.2 EDO08132.1 - 7.1e-30 102.6 0.7 3e-29 100.6 0.0 2.3 3 0 0 3 3 3 1 Scd6-like Sm domain SM-ATX PF14438.1 EDO08132.1 - 1.1e-06 28.4 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.5 EDO08132.1 - 2e-05 25.0 4.0 2e-05 25.0 2.7 2.4 2 0 0 2 2 2 1 FDF domain Ion_trans PF00520.26 EDO08133.1 - 2.6e-13 49.7 14.4 4.6e-13 48.8 10.0 1.4 1 0 0 1 1 1 1 Ion transport protein SpoIISA_toxin PF14171.1 EDO08133.1 - 0.0052 16.0 1.9 0.0052 16.0 1.3 2.2 2 0 0 2 2 2 1 Toxin SpoIISA, type II toxin-antitoxin system AA_permease PF00324.16 EDO08133.1 - 0.096 11.0 10.5 1.1 7.5 3.0 2.6 1 1 1 2 2 2 0 Amino acid permease Matrilin_ccoil PF10393.4 EDO08133.1 - 0.097 12.0 1.2 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin PI31_Prot_C PF08577.6 EDO08134.1 - 0.0071 16.9 8.0 0.0071 16.9 5.5 2.6 1 1 1 2 2 2 1 PI31 proteasome regulator TruB_N PF01509.13 EDO08135.1 - 4.6e-38 130.7 0.3 2.6e-37 128.2 0.2 1.9 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) Metallophos PF00149.23 EDO08136.1 - 0.0001 21.7 0.0 0.00022 20.7 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.1 EDO08136.1 - 0.00012 22.1 2.5 0.017 15.2 0.0 3.5 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.27 EDO08136.1 - 0.0026 16.9 0.3 0.4 10.1 0.0 3.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EDO08136.1 - 0.003 17.2 0.0 0.79 9.7 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain DUF1762 PF08574.5 EDO08136.1 - 0.03 14.7 4.1 0.58 10.6 2.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1762) EF-hand_8 PF13833.1 EDO08136.1 - 0.039 13.5 0.1 9 6.0 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair Pkinase PF00069.20 EDO08137.1 - 7.6e-64 215.3 0.0 8.9e-64 215.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO08137.1 - 1.7e-35 122.3 0.0 2.2e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO08137.1 - 3.3e-05 23.0 0.0 4.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RRM_1 PF00076.17 EDO08138.1 - 1.7e-20 72.3 0.1 3.1e-09 36.3 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO08138.1 - 1.7e-13 50.1 0.0 3.9e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO08138.1 - 2.4e-10 40.2 0.0 1.6e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PCI PF01399.22 EDO08139.1 - 1.5e-11 44.5 2.3 1.6e-11 44.4 0.1 2.3 2 0 0 2 2 2 1 PCI domain PRP21_like_P PF12230.3 EDO08143.1 - 3.6e-40 137.8 5.0 2.5e-39 135.1 3.4 1.9 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EDO08143.1 - 1.8e-33 113.9 0.1 1.4e-15 56.6 0.0 2.7 2 0 0 2 2 2 2 Surp module FinO_N PF12602.3 EDO08143.1 - 2.4 8.5 4.4 0.95 9.8 0.5 2.2 2 1 0 2 2 2 0 Fertility inhibition protein N terminal ABC_tran PF00005.22 EDO08144.1 - 2.1e-32 112.2 0.0 7.2e-18 65.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDO08144.1 - 2.8e-12 46.6 19.5 2.8e-12 46.6 13.5 3.2 3 0 0 3 3 3 1 ABC transporter transmembrane region AAA_21 PF13304.1 EDO08144.1 - 5.6e-07 29.8 0.5 0.39 10.6 0.0 4.1 3 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EDO08144.1 - 1.8e-06 27.4 1.4 0.025 14.0 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 EDO08144.1 - 1.5e-05 24.8 0.0 7.7e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EDO08144.1 - 4.9e-05 23.7 1.9 0.19 12.0 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDO08144.1 - 5.6e-05 23.2 0.1 0.054 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EDO08144.1 - 8.4e-05 21.7 0.3 0.22 10.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin MobB PF03205.9 EDO08144.1 - 0.00013 21.6 0.6 0.37 10.4 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EDO08144.1 - 0.00015 22.2 0.3 0.3 11.5 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EDO08144.1 - 0.00016 21.5 2.1 0.0071 16.1 0.1 2.5 2 0 0 2 2 2 1 Dynamin family UPF0079 PF02367.12 EDO08144.1 - 0.00028 20.4 0.4 0.2 11.3 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 EDO08144.1 - 0.0004 21.2 0.0 0.39 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EDO08144.1 - 0.00044 19.4 0.1 0.31 10.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 EDO08144.1 - 0.00059 18.8 0.2 0.32 9.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EDO08144.1 - 0.0012 18.3 0.0 0.64 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EDO08144.1 - 0.0012 18.7 0.1 0.1 12.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EDO08144.1 - 0.0019 18.3 0.3 3.9 7.6 0.1 3.1 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EDO08144.1 - 0.0019 17.8 0.7 2.2 7.9 0.1 2.8 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.1 EDO08144.1 - 0.0044 16.6 0.9 0.12 11.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDO08144.1 - 0.009 16.3 0.1 4 7.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EDO08144.1 - 0.01 14.6 1.1 0.018 13.8 0.1 1.9 2 0 0 2 2 2 0 ArgK protein Arch_ATPase PF01637.13 EDO08144.1 - 0.022 14.4 0.1 2.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EDO08144.1 - 0.023 14.1 0.3 3.7 6.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 EDO08144.1 - 0.036 13.5 1.8 3.6 7.0 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.13 EDO08144.1 - 0.04 13.4 0.4 0.86 9.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.9 EDO08144.1 - 0.041 12.8 0.0 2.6 6.9 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA_10 PF12846.2 EDO08144.1 - 0.045 13.1 0.6 8 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 EDO08144.1 - 0.047 13.4 0.5 9 6.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain SMC_N PF02463.14 EDO08144.1 - 0.066 12.4 1.1 2.7 7.1 0.1 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain ATP_bind_1 PF03029.12 EDO08144.1 - 0.072 12.6 2.5 4.5 6.7 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 EDO08144.1 - 0.09 12.4 0.7 6.3 6.4 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 EDO08144.1 - 0.11 12.0 0.2 11 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EDO08144.1 - 0.15 11.9 0.2 9.8 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EDO08144.1 - 0.25 11.1 3.8 0.23 11.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF1411 PF07199.6 EDO08145.1 - 0.0099 15.3 0.3 0.033 13.6 0.0 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1411) DUF445 PF04286.7 EDO08145.1 - 0.064 12.7 2.6 0.18 11.3 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF445) GlutR_dimer PF00745.15 EDO08145.1 - 0.18 11.7 3.1 13 5.8 1.3 2.7 2 1 1 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Hormone_1 PF00103.15 EDO08145.1 - 0.22 10.8 1.4 0.53 9.5 0.6 1.7 2 0 0 2 2 2 0 Somatotropin hormone family DUF1411 PF07199.6 EDO08146.1 - 9.4e-06 25.2 0.2 0.0056 16.1 0.1 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1411) PH_3 PF14593.1 EDO08146.1 - 0.062 13.1 0.1 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 PH domain Rabaptin PF03528.10 EDO08147.1 - 0.022 14.6 1.6 0.19 11.6 0.3 2.5 2 0 0 2 2 2 0 Rabaptin Cep57_MT_bd PF06657.8 EDO08147.1 - 0.041 13.8 1.6 0.22 11.4 0.3 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Rho_Binding PF08912.6 EDO08147.1 - 0.11 12.8 4.8 0.12 12.6 0.3 2.8 2 0 0 2 2 2 0 Rho Binding ThiF PF00899.16 EDO08149.1 - 7.9e-32 109.9 4.2 7.1e-24 84.1 0.3 3.2 3 0 0 3 3 3 2 ThiF family UBACT PF02134.16 EDO08149.1 - 1.5e-18 66.1 5.2 5e-18 64.4 0.1 3.7 4 0 0 4 4 4 1 Repeat in ubiquitin-activating (UBA) protein Shikimate_DH PF01488.15 EDO08149.1 - 0.00016 21.7 0.4 0.079 13.0 0.0 3.2 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EDO08149.1 - 0.097 12.9 2.5 0.36 11.1 0.1 3.1 4 0 0 4 4 4 0 Putative NAD(P)-binding DUF1305 PF06996.6 EDO08149.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1305) DEAD PF00270.24 EDO08150.1 - 1.5e-34 118.9 0.0 4.6e-34 117.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO08150.1 - 5e-25 87.1 0.4 1.3e-24 85.8 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain eIF-6 PF01912.13 EDO08151.1 - 1.5e-73 246.1 1.7 4.7e-72 241.2 1.2 2.1 1 1 0 1 1 1 1 eIF-6 family AP_endonuc_2 PF01261.19 EDO08152.1 - 8.1e-25 87.3 0.0 1.6e-24 86.4 0.0 1.4 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel HTH_20 PF12840.2 EDO08154.1 - 0.083 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain WD40 PF00400.27 EDO08155.1 - 7.3e-10 38.3 9.5 0.013 15.3 0.0 6.1 7 1 0 7 7 7 4 WD domain, G-beta repeat Atg8 PF02991.11 EDO08156.1 - 2e-17 63.0 0.1 4.9e-17 61.7 0.1 1.6 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EDO08156.1 - 0.002 18.2 0.1 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 tRNA_Me_trans PF03054.11 EDO08157.1 - 3.8e-98 328.3 0.0 5e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 EDO08157.1 - 5.5e-06 25.9 0.0 2.1e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) SufE PF02657.10 EDO08157.1 - 9.1e-06 25.3 0.0 2.4e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Fe-S metabolism associated domain QueC PF06508.8 EDO08157.1 - 0.019 14.2 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Kp4 PF09044.5 EDO08157.1 - 0.063 13.1 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 Kp4 Asn_synthase PF00733.16 EDO08157.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase NPHI_C PF08469.5 EDO08158.1 - 0.033 14.0 0.0 2 8.2 0.0 2.3 2 0 0 2 2 2 0 Nucleoside triphosphatase I C-terminal DUF1232 PF06803.7 EDO08158.1 - 0.045 13.1 0.1 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) Diphthamide_syn PF01866.12 EDO08159.1 - 1.2e-89 300.5 0.0 2.9e-48 164.6 0.0 2.1 1 1 1 2 2 2 2 Putative diphthamide synthesis protein SET PF00856.23 EDO08161.1 - 1.9e-22 80.3 1.1 1.9e-22 80.3 0.8 3.0 2 1 0 2 2 2 1 SET domain LSM PF01423.17 EDO08162.1 - 3.9e-18 64.7 0.0 5.1e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDO08162.1 - 0.015 15.1 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Lon_C PF05362.8 EDO08163.1 - 6.1e-61 205.3 0.7 2.4e-52 177.2 0.0 2.7 3 0 0 3 3 3 2 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EDO08163.1 - 4.8e-29 101.5 0.0 8.6e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EDO08163.1 - 5.2e-21 75.2 0.0 3.9e-20 72.3 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EDO08163.1 - 5.5e-07 29.1 0.0 1.3e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EDO08163.1 - 1.4e-06 28.1 0.0 3.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EDO08163.1 - 2.8e-06 28.1 0.0 8.7e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EDO08163.1 - 9.5e-06 25.6 0.0 2.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EDO08163.1 - 1.7e-05 24.9 0.0 0.00046 20.3 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EDO08163.1 - 4.1e-05 23.6 0.0 0.00021 21.3 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.6 EDO08163.1 - 4.9e-05 22.1 0.0 8.6e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_18 PF13238.1 EDO08163.1 - 0.00029 21.1 0.3 0.0018 18.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EDO08163.1 - 0.00057 19.3 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EDO08163.1 - 0.00062 18.8 0.0 0.0019 17.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EDO08163.1 - 0.0011 17.7 0.1 0.0056 15.4 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 EDO08163.1 - 0.0036 17.1 0.1 0.047 13.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 EDO08163.1 - 0.012 15.8 0.0 3.2 8.0 0.1 3.0 2 1 0 2 2 2 0 ABC transporter NTPase_1 PF03266.10 EDO08163.1 - 0.017 14.8 0.0 0.082 12.6 0.0 2.2 1 1 1 2 2 2 0 NTPase AAA_10 PF12846.2 EDO08163.1 - 0.03 13.7 0.0 0.82 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Mg_chelatase PF01078.16 EDO08163.1 - 0.034 13.3 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EDO08163.1 - 0.037 13.7 0.1 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 EDO08163.1 - 0.066 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EDO08163.1 - 0.07 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EDO08163.1 - 0.1 11.9 0.4 0.27 10.6 0.1 1.8 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 EDO08163.1 - 0.18 11.6 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Nsp1_C PF05064.8 EDO08164.1 - 8.8e-08 31.7 4.0 8.8e-08 31.7 2.8 2.6 2 1 1 3 3 3 1 Nsp1-like C-terminal region Arfaptin PF06456.8 EDO08164.1 - 0.0016 17.8 7.0 0.29 10.4 0.5 2.1 1 1 1 2 2 2 2 Arfaptin-like domain DASH_Dad3 PF08656.5 EDO08164.1 - 0.0043 16.7 3.0 0.0043 16.7 2.0 2.8 3 1 0 3 3 3 1 DASH complex subunit Dad3 Fez1 PF06818.10 EDO08164.1 - 0.0093 16.0 2.3 0.0093 16.0 1.6 1.7 2 0 0 2 2 2 1 Fez1 Myosin_tail_1 PF01576.14 EDO08164.1 - 0.023 12.4 7.8 0.031 12.0 5.4 1.1 1 0 0 1 1 1 0 Myosin tail CENP-K PF11802.3 EDO08164.1 - 0.028 13.6 4.4 0.04 13.1 3.1 1.2 1 0 0 1 1 1 0 Centromere-associated protein K OmpH PF03938.9 EDO08164.1 - 0.077 12.9 2.3 0.12 12.2 1.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GAS PF13851.1 EDO08164.1 - 0.14 11.3 11.4 0.036 13.2 3.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Surfac_D-trimer PF09006.6 EDO08164.1 - 0.16 11.7 0.5 0.46 10.2 0.3 1.7 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation DUF4164 PF13747.1 EDO08164.1 - 0.17 12.0 6.9 0.37 10.9 0.3 2.6 2 1 1 3 3 2 0 Domain of unknown function (DUF4164) DUF1664 PF07889.7 EDO08164.1 - 0.18 11.6 2.9 3 7.6 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BAG PF02179.11 EDO08164.1 - 0.19 11.8 1.8 0.62 10.2 1.2 1.9 1 1 0 1 1 1 0 BAG domain Med4 PF10018.4 EDO08164.1 - 0.22 10.8 7.8 0.47 9.8 3.7 2.5 1 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 BLOC1_2 PF10046.4 EDO08164.1 - 0.22 11.6 14.7 0.69 10.0 0.0 3.7 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.2 EDO08164.1 - 0.28 11.0 9.8 0.12 12.2 4.9 1.7 2 0 0 2 2 1 0 Tropomyosin like Sec8_exocyst PF04048.9 EDO08164.1 - 0.74 9.4 10.2 0.24 11.0 4.9 1.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Spectrin PF00435.16 EDO08164.1 - 0.94 9.7 6.3 1.4 9.2 3.3 2.1 1 1 1 2 2 2 0 Spectrin repeat Nucleoporin_FG PF13634.1 EDO08164.1 - 1.1 9.5 88.9 0.48 10.6 27.6 2.6 1 1 1 2 2 2 0 Nucleoporin FG repeat region CENP-F_leu_zip PF10473.4 EDO08164.1 - 1.2 9.0 14.3 4.3 7.1 7.1 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 EDO08164.1 - 1.2 8.8 8.6 3.9 7.2 1.6 2.7 2 1 0 2 2 2 0 Laminin Domain II DUF972 PF06156.8 EDO08164.1 - 1.7 9.0 8.0 8.7 6.7 5.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Occludin_ELL PF07303.8 EDO08164.1 - 2.3 8.9 7.6 10 6.9 3.3 2.5 1 1 1 2 2 2 0 Occludin homology domain YlqD PF11068.3 EDO08164.1 - 4.4 7.3 7.7 7.3 6.6 3.2 2.5 1 1 1 3 3 3 0 YlqD protein Fib_alpha PF08702.5 EDO08164.1 - 6.7 6.8 11.7 9.7 6.3 1.7 2.8 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 EDO08164.1 - 8.1 4.7 9.7 16 3.7 6.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) RNA_pol_Rpb4 PF03874.11 EDO08165.1 - 9.1e-19 67.5 0.1 1.2e-18 67.2 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 PCI PF01399.22 EDO08166.1 - 2.4e-08 34.2 0.0 5.7e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.1 EDO08166.1 - 0.0049 16.5 1.3 0.013 15.2 0.3 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDO08166.1 - 0.0071 16.1 1.8 0.012 15.4 0.5 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDO08166.1 - 0.015 15.0 0.0 0.27 11.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO08166.1 - 0.094 12.6 0.1 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO08166.1 - 0.42 10.2 2.2 0.42 10.3 0.4 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat RRP7 PF12923.2 EDO08167.1 - 9.3e-06 25.6 0.1 1.8e-05 24.7 0.1 1.4 1 1 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) VESA1_N PF12785.2 EDO08168.1 - 2.4e-198 659.8 28.1 2.4e-198 659.8 19.5 2.6 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO08169.1 - 1.7e-23 83.3 33.6 2.2e-12 46.7 0.1 4.1 2 1 2 4 4 4 3 Variant erythrocyte surface antigen-1 Abhydrolase_5 PF12695.2 EDO08170.1 - 1.3e-16 60.6 0.0 2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO08170.1 - 5.8e-08 32.8 0.0 6.2e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDO08170.1 - 1.2e-07 31.4 0.4 1.9e-05 24.2 0.2 2.7 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase LIP PF03583.9 EDO08170.1 - 1.5e-05 24.3 0.0 0.0002 20.6 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_3 PF07859.8 EDO08170.1 - 0.0019 17.7 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EDO08170.1 - 0.0052 16.3 0.0 1.1 8.8 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDO08170.1 - 0.015 14.5 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1057 PF06342.7 EDO08170.1 - 0.015 14.1 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) FSH1 PF03959.8 EDO08170.1 - 0.034 13.5 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Thioredoxin_6 PF13848.1 EDO08171.1 - 6.7e-07 29.2 0.2 0.36 10.6 0.0 3.5 2 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.15 EDO08171.1 - 1.1e-06 28.1 0.0 2.7e-05 23.7 0.0 2.9 3 1 0 3 3 3 1 Thioredoxin Thioredoxin_8 PF13905.1 EDO08171.1 - 0.0014 18.6 0.2 0.058 13.5 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EDO08171.1 - 0.0025 17.9 0.0 0.11 12.6 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain KaiB PF07689.7 EDO08171.1 - 0.0056 16.1 0.0 0.018 14.4 0.0 1.9 1 0 0 1 1 1 1 KaiB domain TrbC_Ftype PF09673.5 EDO08171.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein mRNA_cap_enzyme PF01331.14 EDO08172.1 - 1e-45 155.8 0.0 1.4e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EDO08172.1 - 4.4e-11 43.0 0.1 2e-06 28.0 0.1 2.4 1 1 1 2 2 2 2 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EDO08172.1 - 0.00031 20.1 0.0 0.0029 16.9 0.0 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain ABC1 PF03109.11 EDO08173.1 - 1.4e-25 89.5 0.3 3.4e-25 88.3 0.1 1.8 2 0 0 2 2 2 1 ABC1 family Beta-lactamase PF00144.19 EDO08173.1 - 1.8e-22 79.8 0.0 2.3e-20 72.9 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase APH PF01636.18 EDO08173.1 - 0.0022 17.7 0.5 0.0043 16.8 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Metallophos PF00149.23 EDO08174.1 - 4.9e-44 150.1 0.2 5.9e-44 149.8 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-CCHC_2 PF13696.1 EDO08175.1 - 7.8e-05 22.0 2.1 0.00022 20.6 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EDO08175.1 - 0.0001 22.2 11.3 0.0001 22.2 7.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDO08175.1 - 0.00032 20.4 11.5 0.00032 20.4 7.9 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EDO08175.1 - 0.015 15.1 10.1 0.015 15.1 7.0 2.6 3 0 0 3 3 3 0 Ring finger domain zf-RING_6 PF14835.1 EDO08175.1 - 0.022 14.5 7.4 0.07 12.9 5.1 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DHODB_Fe-S_bind PF10418.4 EDO08175.1 - 0.099 12.1 3.7 0.37 10.3 2.5 2.1 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B PhnA_Zn_Ribbon PF08274.7 EDO08175.1 - 0.29 10.9 4.2 0.98 9.2 0.6 2.8 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-C3HC4 PF00097.20 EDO08175.1 - 2.2 8.0 17.8 0.19 11.4 7.9 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.18 EDO08175.1 - 7.2 6.7 9.8 2.8 8.0 3.2 2.8 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_S9 PF00380.14 EDO08176.1 - 1.1e-31 109.5 0.2 1.8e-31 108.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AT_hook PF02178.14 EDO08176.1 - 0.55 10.0 8.9 0.16 11.7 3.8 2.0 2 0 0 2 2 2 0 AT hook motif Nop53 PF07767.6 EDO08177.1 - 7e-27 94.4 13.5 1.1e-22 80.5 9.4 3.0 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF1609 PF07753.6 EDO08177.1 - 0.085 12.1 4.0 0.15 11.3 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) Snapin_Pallidin PF14712.1 EDO08177.1 - 0.83 10.0 6.4 0.095 13.0 0.9 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Gastrin PF00918.12 EDO08177.1 - 4.5 8.1 6.7 4.7 8.0 2.0 2.4 2 0 0 2 2 2 0 Gastrin/cholecystokinin family RNA_pol_Rbc25 PF08292.7 EDO08178.1 - 4.9e-15 55.8 0.0 7.4e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EDO08178.1 - 2.3e-11 43.6 0.1 3.6e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 UCH PF00443.24 EDO08179.1 - 9.6e-36 123.2 0.2 1.4e-35 122.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO08179.1 - 5.8e-21 75.2 0.1 8.7e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Proteasom_Rpn13 PF04683.8 EDO08180.1 - 9.9e-23 80.0 0.0 1.3e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF4094 PF13334.1 EDO08181.1 - 0.39 11.1 1.8 0.74 10.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Helicase_C_2 PF13307.1 EDO08182.1 - 5.3e-41 140.3 0.0 1.2e-40 139.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EDO08182.1 - 2.3e-19 69.4 7.8 3.5e-07 29.7 1.9 3.8 3 0 0 3 3 3 3 DEAD_2 DEAD PF00270.24 EDO08182.1 - 3.6e-06 26.5 0.1 0.00011 21.7 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 EDO08182.1 - 0.001 18.9 0.0 0.0094 15.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EDO08182.1 - 0.002 17.8 0.0 0.006 16.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain RRM_1 PF00076.17 EDO08183.1 - 2.3e-40 136.0 0.1 2.6e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO08183.1 - 5.3e-25 87.1 0.1 3.9e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO08183.1 - 2.3e-20 72.1 0.0 5.1e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EDO08183.1 - 2.6e-05 23.6 0.5 0.012 15.1 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain UDG PF03167.14 EDO08184.1 - 3.5e-27 94.7 0.0 5.4e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily YTH PF04146.10 EDO08185.1 - 9.7e-38 128.9 0.0 1.4e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain zf-CCCH PF00642.19 EDO08185.1 - 4.2e-05 23.0 2.1 0.027 14.1 0.2 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UMP1 PF05348.6 EDO08186.1 - 1.2e-11 44.6 0.0 1.3e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Ribosomal_60s PF00428.14 EDO08187.1 - 3e-24 85.2 8.0 3.7e-24 84.9 5.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DFP PF04127.10 EDO08188.1 - 3.8e-19 69.0 0.2 2.2e-08 33.9 0.1 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein NAD_binding_10 PF13460.1 EDO08188.1 - 0.054 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding DSPc PF00782.15 EDO08189.1 - 3.2e-19 68.8 0.1 5e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDO08189.1 - 0.0014 18.0 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase N2227 PF07942.7 EDO08190.1 - 4.2e-81 271.8 0.0 5.3e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Ribosomal_L9_N PF01281.14 EDO08191.1 - 8.6e-14 50.5 0.7 2.8e-13 48.8 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 EDO08191.1 - 0.088 12.8 0.6 0.19 11.8 0.4 1.5 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain DcpS_C PF11969.3 EDO08192.1 - 2.7e-05 24.3 0.4 0.016 15.4 0.0 2.4 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding BDV_P24 PF06595.6 EDO08192.1 - 0.092 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Borna disease virus P24 protein PWI PF01480.12 EDO08193.1 - 2.6e-33 113.9 0.0 3.8e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 PWI domain DUF632 PF04782.7 EDO08193.1 - 4.8 6.1 8.5 18 4.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF632) YTH PF04146.10 EDO08194.1 - 1.2e-39 135.1 0.0 1.9e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain HD_4 PF13328.1 EDO08194.1 - 0.025 14.2 0.0 0.072 12.8 0.0 1.7 2 0 0 2 2 2 0 HD domain EMP24_GP25L PF01105.19 EDO08195.1 - 7.3e-22 77.9 0.1 8.5e-22 77.7 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pox_MCEL PF03291.11 EDO08196.1 - 1.9e-44 151.8 0.0 3.1e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 EDO08196.1 - 7.3e-10 38.7 0.0 1.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO08196.1 - 8e-09 35.8 0.0 1.8e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO08196.1 - 6.1e-08 33.0 0.0 1.6e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO08196.1 - 1.2e-07 31.4 0.0 2.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO08196.1 - 6.3e-07 29.7 0.0 1.6e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO08196.1 - 1e-05 26.0 0.0 2.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO08196.1 - 0.0048 16.9 0.0 0.0091 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain LCCL PF03815.14 EDO08197.1 - 2.3e-23 82.0 0.9 7.5e-23 80.3 0.6 1.9 1 0 0 1 1 1 1 LCCL domain Ricin_B_lectin PF00652.17 EDO08197.1 - 1.9e-10 40.8 0.1 3.3e-09 36.8 0.1 2.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain DUF1080 PF06439.6 EDO08197.1 - 0.00013 21.8 0.0 0.00065 19.6 0.0 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1080) Fibrinogen_C PF00147.13 EDO08197.1 - 0.0037 16.8 0.0 0.0037 16.8 0.0 2.1 3 0 0 3 3 3 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF3161 PF11362.3 EDO08198.1 - 3e-09 36.6 0.0 6.9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3161) BAR PF03114.13 EDO08198.1 - 0.01 15.3 1.1 0.013 14.9 0.7 1.1 1 0 0 1 1 1 0 BAR domain COP23 PF14218.1 EDO08198.1 - 0.021 14.3 0.1 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Circadian oscillating protein COP23 SNARE PF05739.14 EDO08199.1 - 1.8e-10 40.3 6.6 2.7e-10 39.7 2.3 2.7 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EDO08199.1 - 5.7e-05 23.2 13.9 0.00029 20.9 2.4 2.7 2 1 2 4 4 4 2 Syntaxin Syntaxin-6_N PF09177.6 EDO08199.1 - 0.0019 18.5 8.2 0.033 14.5 0.3 3.6 2 1 1 3 3 3 1 Syntaxin 6, N-terminal DUF148 PF02520.12 EDO08199.1 - 0.0049 16.6 6.5 0.24 11.1 0.4 3.0 2 1 1 3 3 3 2 Domain of unknown function DUF148 Tup_N PF08581.5 EDO08199.1 - 0.0084 16.2 9.9 0.052 13.7 0.3 3.1 3 1 1 4 4 4 2 Tup N-terminal Vps53_N PF04100.7 EDO08199.1 - 0.0089 14.8 1.8 0.0089 14.8 1.2 2.1 1 1 1 2 2 2 1 Vps53-like, N-terminal V-SNARE PF05008.10 EDO08199.1 - 0.011 15.9 7.3 0.94 9.6 0.4 3.6 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF1351 PF07083.6 EDO08199.1 - 0.011 15.3 0.6 0.011 15.3 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) HSBP1 PF06825.7 EDO08199.1 - 0.035 13.6 4.3 0.17 11.4 1.2 2.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Med9 PF07544.8 EDO08199.1 - 0.051 13.3 6.9 2.1 8.1 0.1 3.1 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.7 EDO08199.1 - 0.073 12.8 8.3 3.1 7.6 1.1 3.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vac_Fusion PF02346.11 EDO08199.1 - 0.09 12.2 3.8 5.8 6.4 0.0 2.8 2 1 1 3 3 3 0 Chordopoxvirus fusion protein FlaC_arch PF05377.6 EDO08199.1 - 0.14 12.0 5.8 3.9 7.4 0.0 4.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) ACCA PF03255.9 EDO08199.1 - 0.19 11.2 9.0 0.18 11.3 0.8 3.1 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit AAA_13 PF13166.1 EDO08199.1 - 0.23 9.8 8.6 0.08 11.3 3.4 1.8 1 1 0 2 2 2 0 AAA domain TBPIP PF07106.8 EDO08199.1 - 0.24 10.9 9.5 0.036 13.6 1.3 2.6 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF310 PF03750.8 EDO08199.1 - 0.25 11.5 5.5 0.89 9.7 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF310) NPV_P10 PF05531.7 EDO08199.1 - 0.28 11.4 5.1 0.93 9.7 0.1 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Tweety PF04906.8 EDO08199.1 - 0.8 8.0 9.3 0.44 8.9 0.1 2.9 1 1 2 3 3 3 0 Tweety Ead_Ea22 PF13935.1 EDO08199.1 - 2.6 8.3 8.1 0.62 10.4 1.5 2.4 2 2 0 2 2 2 0 Ead/Ea22-like protein IncA PF04156.9 EDO08199.1 - 2.6 7.5 13.7 0.95 9.0 5.1 2.2 2 0 0 2 2 2 0 IncA protein Tropomyosin_1 PF12718.2 EDO08199.1 - 5.5 6.8 9.7 1.5 8.6 3.2 2.4 1 1 1 2 2 2 0 Tropomyosin like Syntaxin_2 PF14523.1 EDO08199.1 - 6.2 6.9 11.0 13 5.9 2.5 3.1 2 1 1 3 3 3 0 Syntaxin-like protein Ribosomal_L14 PF00238.14 EDO08200.1 - 2.1e-35 121.1 0.0 2.3e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e tRNA-synt_1c PF00749.16 EDO08201.1 - 6.2e-94 314.1 0.0 5e-93 311.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EDO08201.1 - 3.9e-39 134.1 0.0 6.2e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain PTPLA PF04387.9 EDO08202.1 - 2.6e-10 39.9 1.7 2.6e-10 39.9 1.2 1.4 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA HSA PF07529.8 EDO08203.1 - 0.0094 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 HSA RPAP1_N PF08621.5 EDO08203.1 - 0.089 12.3 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 RPAP1-like, N-terminal Pkinase PF00069.20 EDO08204.1 - 3.9e-48 163.8 0.0 6.3e-37 127.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO08204.1 - 7e-23 81.0 0.0 1.8e-22 79.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Thymidylate_kin PF02223.12 EDO08205.1 - 3.1e-36 124.4 0.0 3.7e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 EDO08205.1 - 0.0059 15.8 0.1 0.045 12.9 0.1 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 EDO08205.1 - 0.023 14.6 0.0 0.034 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EDO08206.1 - 3e-31 108.5 0.0 8.4e-17 61.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDO08206.1 - 2.1e-13 50.2 17.9 2.1e-13 50.2 12.4 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_23 PF13476.1 EDO08206.1 - 8.3e-06 26.2 4.3 0.0084 16.4 0.3 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EDO08206.1 - 1.5e-05 24.4 2.9 0.018 14.5 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EDO08206.1 - 8.9e-05 21.9 0.0 0.48 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EDO08206.1 - 9.7e-05 22.4 3.1 0.42 10.5 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 EDO08206.1 - 0.00011 22.9 0.0 0.44 11.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EDO08206.1 - 0.00017 20.8 1.5 0.3 10.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 EDO08206.1 - 0.00072 18.5 0.8 0.14 11.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 EDO08206.1 - 0.0012 19.3 2.9 0.22 12.0 0.2 2.8 2 0 0 2 2 2 1 Miro-like protein UPF0079 PF02367.12 EDO08206.1 - 0.0017 17.9 0.7 0.098 12.2 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EDO08206.1 - 0.0019 17.3 0.3 0.16 11.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 EDO08206.1 - 0.002 18.1 0.5 0.41 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EDO08206.1 - 0.0023 17.6 2.1 0.2 11.3 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase Dynamin_N PF00350.18 EDO08206.1 - 0.0036 17.1 4.1 0.017 14.9 0.2 2.5 2 0 0 2 2 2 1 Dynamin family NACHT PF05729.7 EDO08206.1 - 0.004 16.8 0.7 0.6 9.7 0.1 2.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EDO08206.1 - 0.0041 17.2 1.4 0.39 10.8 0.1 2.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EDO08206.1 - 0.0064 16.2 2.0 0.9 9.2 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EDO08206.1 - 0.0087 15.7 0.5 1.6 8.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EDO08206.1 - 0.009 16.3 0.0 8.1 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EDO08206.1 - 0.0097 15.8 2.7 0.66 9.9 0.3 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ArgK PF03308.11 EDO08206.1 - 0.029 13.1 0.7 0.34 9.6 0.1 2.2 2 0 0 2 2 2 0 ArgK protein AAA_30 PF13604.1 EDO08206.1 - 0.033 13.7 0.3 2.3 7.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EDO08206.1 - 0.039 13.0 0.1 5.5 5.9 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain SMC_N PF02463.14 EDO08206.1 - 0.056 12.6 2.6 1 8.5 0.2 2.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 EDO08206.1 - 0.096 12.1 2.1 4.9 6.5 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EDO08206.1 - 0.12 12.1 1.8 2.1 8.0 0.1 2.4 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.13 EDO08206.1 - 0.12 11.7 1.2 11 5.4 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EDO08206.1 - 0.14 11.5 1.9 5 6.4 0.2 2.3 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 EDO08206.1 - 0.35 10.6 4.3 0.31 10.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF1411 PF07199.6 EDO08207.1 - 0.0007 19.0 0.7 0.0013 18.1 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1411) DUF1411 PF07199.6 EDO08209.1 - 0.013 14.9 1.6 0.022 14.1 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1411) Ycf1 PF05758.7 EDO08209.1 - 0.048 11.3 5.6 0.045 11.4 3.9 1.1 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 EDO08209.1 - 0.22 9.1 12.0 0.26 8.9 8.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NARP1 PF12569.3 EDO08209.1 - 0.26 9.9 13.2 0.33 9.6 9.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4604 PF15377.1 EDO08209.1 - 1.2 9.2 22.5 2.3 8.4 15.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DDHD PF02862.12 EDO08209.1 - 3.2 7.4 11.2 3.5 7.3 7.2 1.5 1 1 0 1 1 1 0 DDHD domain OmpH PF03938.9 EDO08209.1 - 4.1 7.3 11.9 7 6.5 8.3 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Phosducin PF02114.11 EDO08209.1 - 6.2 5.4 10.8 12 4.5 7.5 1.4 1 0 0 1 1 1 0 Phosducin DUF4611 PF15387.1 EDO08209.1 - 7.5 6.7 24.6 0.069 13.2 3.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) CDC45 PF02724.9 EDO08209.1 - 9.8 4.0 19.5 14 3.5 13.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1411 PF07199.6 EDO08211.1 - 0.02 14.3 2.3 0.023 14.1 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1411) Hid1 PF12722.2 EDO08211.1 - 0.071 10.7 12.8 0.085 10.5 8.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 EDO08211.1 - 0.12 10.0 5.5 0.13 9.9 3.8 1.2 1 0 0 1 1 1 0 Ycf1 Hex_IIIa PF02455.11 EDO08211.1 - 0.99 8.0 5.8 1.3 7.5 4.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Nop14 PF04147.7 EDO08211.1 - 1.2 6.9 24.2 1.6 6.5 16.8 1.2 1 0 0 1 1 1 0 Nop14-like family RP-C_C PF11800.3 EDO08211.1 - 2.4 7.7 7.1 4.9 6.7 4.9 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF572 PF04502.8 EDO08211.1 - 7.7 5.6 21.6 6.7 5.8 12.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF1411 PF07199.6 EDO08215.1 - 0.0025 17.2 0.2 0.0077 15.6 0.0 1.8 2 1 1 3 3 3 1 Protein of unknown function (DUF1411) DUF3216 PF11505.3 EDO08215.1 - 0.024 14.4 0.0 0.15 11.8 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3216) Syntaxin PF00804.20 EDO08215.1 - 0.074 13.2 1.0 0.42 10.7 0.8 2.0 1 1 1 2 2 2 0 Syntaxin DUF2281 PF10047.4 EDO08215.1 - 0.11 12.8 2.4 1.6 9.0 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2281) DUF4175 PF13779.1 EDO08215.1 - 0.12 10.0 4.3 0.18 9.4 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Nucleoporin_FG PF13634.1 EDO08216.1 - 3.6e-17 62.6 201.6 1.7e-08 34.6 29.5 6.2 2 1 4 6 6 6 5 Nucleoporin FG repeat region Ribosomal_L18e PF00828.14 EDO08217.1 - 4.4e-34 117.6 0.4 5.2e-34 117.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 TRAPP PF04051.11 EDO08218.1 - 5e-26 91.0 0.0 5.7e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF1042 PF06294.6 EDO08218.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1042) RelB_N PF12910.2 EDO08219.1 - 0.11 11.8 0.1 0.66 9.3 0.0 2.1 2 0 0 2 2 2 0 Antitoxin of toxin-antitoxin stability system N-terminal Sedlin_N PF04628.8 EDO08222.1 - 2.2e-32 111.6 0.0 2.8e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PAP_assoc PF03828.14 EDO08223.1 - 0.0028 17.5 0.1 0.0062 16.4 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase Peptidase_C54 PF03416.14 EDO08223.1 - 0.026 13.6 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C54 Cpn10 PF00166.16 EDO08224.1 - 2.3e-29 101.1 0.1 8.3e-14 51.2 0.0 2.3 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit tRNA-synt_1 PF00133.17 EDO08225.1 - 1.3e-204 680.6 0.0 1.7e-204 680.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EDO08225.1 - 1e-20 73.7 1.3 1.9e-07 30.1 0.4 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EDO08225.1 - 1.6e-18 66.9 0.1 6.3e-18 64.9 0.0 2.1 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EDO08225.1 - 0.0028 16.8 0.0 0.0085 15.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Rapamycin_bind PF08771.6 EDO08226.1 - 0.12 12.4 0.1 0.3 11.2 0.1 1.6 1 0 0 1 1 1 0 Rapamycin binding domain JAB PF01398.16 EDO08227.1 - 6e-06 25.9 0.0 0.00037 20.2 0.0 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2170 PF09938.4 EDO08227.1 - 0.079 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) Ribosomal_L7Ae PF01248.21 EDO08229.1 - 5.7e-23 80.2 0.0 6.5e-23 80.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family APP_Cu_bd PF12924.2 EDO08229.1 - 0.014 15.8 0.1 0.059 13.8 0.1 2.0 1 1 1 2 2 2 0 Copper-binding of amyloid precursor, CuBD Adaptin_N PF01602.15 EDO08230.1 - 1.1e-118 396.9 0.7 1.6e-118 396.2 0.5 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EDO08230.1 - 3.9e-21 75.6 0.1 1.2e-19 70.8 0.0 2.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EDO08230.1 - 1.2e-13 51.1 4.6 3.1e-10 40.2 0.0 5.2 5 1 2 7 7 7 2 HEAT repeats HEAT PF02985.17 EDO08230.1 - 1.2e-12 46.7 0.6 0.0012 18.7 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EDO08230.1 - 6e-05 23.3 0.8 0.56 10.7 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat Arm PF00514.18 EDO08230.1 - 0.00061 19.5 0.0 0.043 13.6 0.0 3.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 EDO08230.1 - 0.0053 15.9 0.0 0.015 14.3 0.0 1.7 1 0 0 1 1 1 1 Armadillo-like Alpha_adaptinC2 PF02883.15 EDO08230.1 - 0.0089 16.3 0.1 0.017 15.4 0.1 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain CLASP_N PF12348.3 EDO08230.1 - 0.026 13.9 0.0 0.71 9.1 0.0 2.8 2 1 1 3 3 3 0 CLASP N terminal Cohesin_HEAT PF12765.2 EDO08230.1 - 0.068 13.1 0.0 1.9 8.5 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion PCI_Csn8 PF10075.4 EDO08231.1 - 1.1e-19 70.6 0.0 1.5e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EDO08231.1 - 5.7e-10 39.0 0.1 8.6e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DAD PF02109.11 EDO08232.1 - 0.034 14.2 0.4 2.1 8.4 0.3 2.1 1 1 1 2 2 2 0 DAD family Sybindin PF04099.7 EDO08233.1 - 1.4e-37 128.5 0.1 1.6e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EDO08233.1 - 1.1e-06 28.5 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PI3_PI4_kinase PF00454.22 EDO08235.1 - 3.6e-32 111.7 0.0 7.2e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase tRNA-synt_1 PF00133.17 EDO08236.1 - 8.1e-63 212.3 1.7 1.3e-43 148.9 0.4 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EDO08236.1 - 2.4e-13 49.5 0.5 1.5e-06 27.1 0.0 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EDO08236.1 - 0.0051 15.9 0.1 0.56 9.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EDO08236.1 - 0.015 15.0 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA zf-HC5HC2H_2 PF13832.1 EDO08237.1 - 1.2e-30 105.7 37.9 1.6e-18 66.6 3.5 4.9 4 1 0 4 4 4 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EDO08237.1 - 2.5e-12 46.7 12.6 6.3e-09 35.8 3.8 6.0 3 2 3 6 6 6 3 PHD-like zinc-binding domain PHD PF00628.24 EDO08237.1 - 5.9e-12 45.0 48.4 3.1e-05 23.5 2.7 5.7 5 0 0 5 5 5 4 PHD-finger PHD_2 PF13831.1 EDO08237.1 - 8.4e-09 34.6 2.2 8.4e-09 34.6 1.5 5.5 4 1 0 4 4 4 3 PHD-finger HAP2-GCS1 PF10699.4 EDO08238.1 - 1.4e-19 69.7 1.2 3e-19 68.7 0.0 2.2 2 0 0 2 2 2 1 Male gamete fusion factor Ras PF00071.17 EDO08239.1 - 9.5e-43 145.3 0.5 1.8e-40 137.9 0.4 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EDO08239.1 - 1.6e-15 57.6 0.1 5.8e-15 55.8 0.1 1.9 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO08239.1 - 2.5e-13 49.6 0.1 9.2e-11 41.2 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDO08239.1 - 2.9e-06 26.8 0.1 4.4e-06 26.2 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EDO08239.1 - 0.00084 18.9 0.1 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EDO08239.1 - 0.0042 17.0 0.0 0.009 15.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDO08239.1 - 0.0053 16.5 0.3 0.026 14.3 0.2 2.0 1 1 0 1 1 1 1 Dynamin family Gtr1_RagA PF04670.7 EDO08239.1 - 0.0062 15.7 0.1 0.014 14.5 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region rve_2 PF13333.1 EDO08241.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Cyclin_N PF00134.18 EDO08242.1 - 2.6e-06 27.0 0.5 5.9e-06 25.8 0.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF2009 PF09418.5 EDO08243.1 - 2.4e-186 620.0 2.3 3.7e-118 395.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2009) CAF1 PF04857.15 EDO08244.1 - 1.3e-64 218.1 0.2 1.9e-64 217.5 0.1 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease DUF647 PF04884.9 EDO08246.1 - 8e-24 84.1 4.8 1.3e-23 83.4 3.3 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis tRNA-synt_1 PF00133.17 EDO08247.1 - 9.6e-37 126.2 0.0 4.6e-21 74.4 0.0 4.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EDO08247.1 - 1.8e-17 63.0 0.0 1.5e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EDO08247.1 - 1.3e-15 57.4 0.0 2.6e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EDO08247.1 - 6e-09 35.4 0.0 1.7e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Baculo_VP1054 PF05789.6 EDO08247.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Baculovirus VP1054 protein tRNA-synt_1f PF01921.13 EDO08247.1 - 0.057 12.0 0.0 0.18 10.4 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (K) Mito_carr PF00153.22 EDO08248.1 - 4.9e-32 109.4 3.1 8e-11 41.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cullin PF00888.17 EDO08249.1 - 3.3e-43 148.1 7.9 3.2e-42 144.8 5.5 2.0 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EDO08249.1 - 0.019 14.7 0.4 0.076 12.8 0.3 2.1 1 1 0 1 1 1 0 Cullin protein neddylation domain DUF3437 PF11919.3 EDO08250.1 - 2.7e-25 87.9 0.0 1.4e-24 85.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) Metal_resist PF13801.1 EDO08250.1 - 0.38 10.7 0.0 0.68 9.9 0.0 1.4 1 0 0 1 1 1 0 Heavy-metal resistance Fe-S_biosyn PF01521.15 EDO08251.1 - 8.6e-11 41.7 0.0 9.8e-11 41.5 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Pox_F12L PF03337.8 EDO08252.1 - 0.054 11.4 0.0 0.081 10.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein VESA1_N PF12785.2 EDO08253.1 - 3e-19 69.3 1.6 3e-19 69.3 1.1 3.7 4 1 0 4 4 4 1 Variant erythrocyte surface antigen-1 SNF2_N PF00176.18 EDO08255.1 - 8.5e-54 182.3 0.1 1.5e-53 181.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.24 EDO08255.1 - 6.3e-18 64.2 79.5 5.7e-10 38.7 4.2 6.8 6 1 0 6 6 6 4 PHD-finger Helicase_C PF00271.26 EDO08255.1 - 5.6e-14 51.7 0.0 1.9e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-PHD-like PF15446.1 EDO08255.1 - 3.4e-08 32.9 40.6 0.0009 18.5 4.8 6.3 3 2 2 6 6 6 5 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 EDO08255.1 - 1.7e-06 27.6 11.5 3.2e-06 26.7 1.6 7.2 6 2 0 7 7 7 2 Prokaryotic RING finger family 1 ResIII PF04851.10 EDO08255.1 - 1.9e-05 24.6 0.0 0.00012 21.9 0.0 2.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDO08255.1 - 4.4e-05 23.0 0.0 0.00012 21.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase C1_1 PF00130.17 EDO08255.1 - 0.0002 21.0 7.5 0.0018 17.9 1.1 8.1 7 2 2 9 9 9 3 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EDO08255.1 - 0.00055 19.1 1.0 0.00055 19.1 0.7 7.8 9 0 0 9 9 9 3 PHD-finger AAA_14 PF13173.1 EDO08255.1 - 0.064 13.1 0.6 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EDO08256.1 - 1.1e-31 109.7 0.0 1.7e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO08256.1 - 0.00017 21.5 0.0 0.00047 20.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EDO08256.1 - 0.029 14.5 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EDO08256.1 - 0.061 12.5 0.3 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDO08256.1 - 0.073 12.8 0.1 5.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Dynamin family SRPRB PF09439.5 EDO08256.1 - 0.13 11.4 0.1 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Nop52 PF05997.7 EDO08257.1 - 2.2e-56 190.7 6.9 2.2e-56 190.7 4.8 1.9 2 1 0 2 2 2 1 Nucleolar protein,Nop52 DUF1090 PF06476.7 EDO08257.1 - 0.007 16.0 3.4 0.56 9.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1090) Nipped-B_C PF12830.2 EDO08257.1 - 0.048 13.2 1.6 0.08 12.5 0.4 1.8 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus NifU PF01106.12 EDO08258.1 - 2.5e-18 65.6 0.2 3.3e-18 65.1 0.2 1.2 1 0 0 1 1 1 1 NifU-like domain Ank_2 PF12796.2 EDO08259.1 - 3.9e-63 209.7 13.4 2.6e-18 66.1 0.8 4.9 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EDO08259.1 - 3e-33 111.9 8.8 0.0015 18.2 0.0 10.5 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 EDO08259.1 - 4.4e-28 97.1 6.4 4.4e-08 33.4 0.0 7.7 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDO08259.1 - 3.7e-26 90.5 2.0 9.4e-09 35.2 0.1 6.8 3 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO08259.1 - 4.2e-25 85.2 9.4 0.0062 16.6 0.0 9.8 10 0 0 10 10 10 7 Ankyrin repeat LRR_6 PF13516.1 EDO08259.1 - 0.081 13.0 2.6 5.2 7.4 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Kelch_3 PF13415.1 EDO08260.1 - 3.2e-32 109.9 14.1 5.3e-08 32.8 0.0 7.9 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EDO08260.1 - 7.7e-30 102.4 10.4 6.9e-08 32.1 0.0 6.6 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EDO08260.1 - 1.4e-24 85.2 13.2 7.7e-08 32.1 0.0 6.3 4 1 2 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EDO08260.1 - 3.4e-23 81.1 8.0 4.2e-05 23.3 0.1 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EDO08260.1 - 9.5e-12 44.2 18.6 0.00077 18.9 0.1 6.4 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EDO08260.1 - 1.6e-08 34.0 13.2 0.071 12.9 0.0 6.1 6 0 0 6 6 6 4 Kelch motif PK PF00224.16 EDO08261.1 - 6.8e-138 459.0 2.4 8.7e-138 458.6 1.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EDO08261.1 - 3.1e-22 78.3 1.3 8.7e-22 76.8 0.9 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HTH_DeoR PF08220.7 EDO08261.1 - 0.14 11.7 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain adh_short PF00106.20 EDO08263.1 - 5.6e-20 71.9 0.0 8.9e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EDO08263.1 - 5.1e-09 35.9 0.0 6.9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EDO08263.1 - 1.1e-07 31.7 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDO08263.1 - 1.3e-07 31.6 0.1 2.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TIR-like PF10137.4 EDO08263.1 - 0.0051 16.4 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 Predicted nucleotide-binding protein containing TIR-like domain 3Beta_HSD PF01073.14 EDO08263.1 - 0.018 13.7 0.0 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 EDO08263.1 - 0.066 12.2 0.1 0.14 11.1 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EDO08263.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding HAD PF12710.2 EDO08263.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RNase_PH PF01138.16 EDO08264.1 - 9.5e-06 25.9 0.0 4e-05 23.9 0.0 2.0 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EDO08264.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 AP2 PF00847.15 EDO08265.1 - 4.8e-05 23.4 3.2 8.5e-05 22.6 2.2 1.5 1 0 0 1 1 1 1 AP2 domain UCR_UQCRX_QCR9 PF05365.7 EDO08266.1 - 9e-06 25.2 0.0 2.3e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like RAP PF08373.5 EDO08267.1 - 2.8e-10 39.8 0.1 7.7e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 RAP domain Rep_fac_C PF08542.6 EDO08268.1 - 0.0034 17.3 1.3 0.47 10.4 0.0 3.2 3 0 0 3 3 3 2 Replication factor C C-terminal domain PIG-L PF02585.12 EDO08269.1 - 1.7e-22 80.3 0.0 2.2e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP11 PF06644.6 EDO08269.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein Sarcolipin PF05366.6 EDO08269.1 - 1.7 8.1 4.7 17 4.9 0.1 2.5 2 0 0 2 2 2 0 Sarcolipin Proteasome PF00227.21 EDO08270.1 - 5.3e-43 146.5 0.0 6e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit VESA1_N PF12785.2 EDO08272.1 - 9.7e-19 67.6 3.2 9.7e-19 67.6 2.3 3.2 3 1 0 3 3 3 1 Variant erythrocyte surface antigen-1 Fe-S_biosyn PF01521.15 EDO08274.1 - 1.2e-10 41.3 0.1 1.3e-10 41.1 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis VESA1_N PF12785.2 EDO08275.1 - 1.4e-12 47.3 5.7 7.4e-08 31.7 0.0 5.0 6 1 0 6 6 6 2 Variant erythrocyte surface antigen-1 Thioredoxin_7 PF13899.1 EDO08276.1 - 0.00064 19.6 0.3 0.0014 18.5 0.2 1.6 1 0 0 1 1 1 1 Thioredoxin-like Atrophin-1 PF03154.10 EDO08276.1 - 0.072 11.2 1.1 0.097 10.7 0.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family Thioredoxin PF00085.15 EDO08276.1 - 0.19 11.4 2.0 0.23 11.1 0.2 2.1 1 1 1 2 2 2 0 Thioredoxin TMF_TATA_bd PF12325.3 EDO08276.1 - 0.44 10.2 14.1 0.55 9.9 4.5 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF2570 PF10828.3 EDO08276.1 - 0.93 9.1 17.3 0.54 9.8 8.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) CENP-Q PF13094.1 EDO08276.1 - 3.9 7.4 12.7 14 5.6 6.5 2.8 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Microtub_assoc PF07989.6 EDO08276.1 - 4.6 7.1 11.6 0.16 11.7 3.2 2.2 3 0 0 3 3 3 0 Microtubule associated Sec2p PF06428.6 EDO08276.1 - 4.9 7.0 13.9 4.7 7.1 0.3 2.8 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p AAA PF00004.24 EDO08277.1 - 2.2e-08 34.3 0.2 1.5e-07 31.7 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EDO08277.1 - 4.3e-07 29.0 0.1 1e-05 24.4 0.0 2.4 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EDO08277.1 - 1.8e-06 28.7 0.2 9.1e-06 26.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EDO08277.1 - 9.6e-05 21.6 0.0 0.00022 20.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDO08277.1 - 0.00019 21.5 0.7 0.0045 17.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EDO08277.1 - 0.00023 21.4 0.2 0.0016 18.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO08277.1 - 0.00055 19.9 1.4 0.016 15.2 0.0 3.3 1 1 3 4 4 4 1 AAA ATPase domain AAA_5 PF07728.9 EDO08277.1 - 0.0013 18.4 0.0 0.0042 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EDO08277.1 - 0.0015 18.4 0.0 0.0057 16.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDO08277.1 - 0.0032 16.5 0.0 0.0087 15.1 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EDO08277.1 - 0.02 14.6 0.0 0.071 12.8 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain DsrC PF04358.8 EDO08277.1 - 0.021 15.0 0.1 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 DsrC like protein AAA_33 PF13671.1 EDO08277.1 - 0.026 14.3 0.0 0.075 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EDO08277.1 - 0.029 14.6 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.1 EDO08277.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain LexA_DNA_bind PF01726.11 EDO08277.1 - 0.09 12.3 0.1 1.7 8.3 0.0 2.7 2 0 0 2 2 2 0 LexA DNA binding domain PAP2_C PF14360.1 EDO08278.1 - 7.3e-16 58.2 9.5 7.3e-16 58.2 6.6 2.3 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 EDO08278.1 - 7.1e-07 28.9 7.9 7.1e-07 28.9 5.5 1.8 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EDO08278.1 - 0.0065 16.0 9.9 0.0065 16.0 6.8 2.0 2 1 0 2 2 2 1 PAP2 superfamily Peptidase_M50 PF02163.17 EDO08278.1 - 0.09 11.7 0.1 0.23 10.3 0.1 1.7 1 1 0 1 1 1 0 Peptidase family M50 Mito_carr PF00153.22 EDO08279.1 - 3.3e-06 26.7 0.1 0.017 14.8 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein PA14 PF07691.7 EDO08281.1 - 2.7e-17 62.7 0.0 8.8e-17 61.1 0.0 1.9 2 0 0 2 2 2 1 PA14 domain fn2 PF00040.14 EDO08281.1 - 0.077 13.0 1.0 0.2 11.6 0.7 1.8 1 0 0 1 1 1 0 Fibronectin type II domain Ded_cyto PF06920.8 EDO08281.1 - 0.096 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Dedicator of cytokinesis NUDIX_2 PF13869.1 EDO08282.1 - 4.1e-58 195.8 0.0 6.1e-58 195.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotide hydrolase Acetyltransf_1 PF00583.19 EDO08284.1 - 1.2e-11 44.4 0.0 1.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO08284.1 - 4.2e-07 30.0 0.1 6.2e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO08284.1 - 4.4e-07 30.0 0.0 5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDO08284.1 - 1.2e-05 25.0 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EDO08284.1 - 3.2e-05 24.1 0.0 3.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDO08284.1 - 0.00085 19.2 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EDO08284.1 - 0.035 14.0 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDO08284.1 - 0.043 13.6 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA-synt_2d PF01409.15 EDO08285.1 - 1e-57 195.1 0.0 1.4e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EDO08285.1 - 6.6e-07 29.0 0.0 4.9e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EDO08285.1 - 0.00012 21.0 2.0 0.00031 19.6 0.1 2.3 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Mre11_DNA_bind PF04152.9 EDO08286.1 - 8.6e-19 68.0 0.0 1.9e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EDO08286.1 - 3.3e-18 65.8 1.3 8e-18 64.5 0.9 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDO08286.1 - 1.5e-08 34.5 0.0 2.3e-07 30.7 0.0 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Iso_dh PF00180.15 EDO08287.1 - 2.3e-63 214.2 0.0 2.7e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.6 EDO08287.1 - 0.089 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Phenylalanine zipper UAE_UbL PF14732.1 EDO08289.1 - 0.13 12.3 0.1 0.26 11.4 0.0 1.5 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Fe-S_biosyn PF01521.15 EDO08290.1 - 1e-10 41.5 0.0 1.5e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Homeobox_KN PF05920.6 EDO08290.1 - 0.13 11.9 0.0 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Homeobox KN domain D123 PF07065.9 EDO08291.1 - 4.4e-21 75.2 0.5 2.4e-20 72.8 0.4 1.9 1 1 0 1 1 1 1 D123 Sec1 PF00995.18 EDO08292.1 - 2.1e-43 148.8 0.0 3.6e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Sec1 family ATP-synt_F6 PF05511.6 EDO08292.1 - 0.24 11.3 0.9 2.6 8.0 0.0 3.1 4 0 0 4 4 4 0 Mitochondrial ATP synthase coupling factor 6 OTU PF02338.14 EDO08293.1 - 7.1e-08 33.0 0.0 2.2e-06 28.2 0.0 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease HAD_2 PF13419.1 EDO08294.1 - 0.0076 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase OTU PF02338.14 EDO08294.1 - 0.0093 16.5 0.0 0.86 10.2 0.0 2.3 2 0 0 2 2 2 2 OTU-like cysteine protease GATA PF00320.22 EDO08295.1 - 4.4e-07 29.1 3.8 1e-06 27.9 2.6 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF164 PF02591.10 EDO08295.1 - 0.014 15.2 5.0 0.087 12.6 3.5 2.1 1 1 0 1 1 1 0 Putative zinc ribbon domain SRR PF07709.6 EDO08296.1 - 0.068 13.3 0.0 5.1 7.7 0.0 2.8 3 0 0 3 3 3 0 Seven Residue Repeat RVT_3 PF13456.1 EDO08296.1 - 0.078 12.7 0.5 0.13 12.0 0.2 1.5 1 1 0 1 1 1 0 Reverse transcriptase-like Ras PF00071.17 EDO08297.1 - 6.9e-60 201.1 0.0 8.1e-60 200.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO08297.1 - 1.5e-18 67.3 0.0 2.4e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO08297.1 - 8.3e-16 57.7 0.0 1.1e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDO08297.1 - 5.8e-07 28.8 0.0 6.8e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO08297.1 - 5.8e-05 22.6 0.0 9.8e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO08297.1 - 9.3e-05 22.3 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EDO08297.1 - 0.0013 17.9 0.0 0.0017 17.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EDO08297.1 - 0.0067 16.5 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain CENP-M PF11111.3 EDO08297.1 - 0.051 12.8 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) G-alpha PF00503.15 EDO08297.1 - 0.06 12.0 0.3 2.6 6.6 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Cas_Cas5d PF09704.5 EDO08297.1 - 0.071 12.7 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) DUF258 PF03193.11 EDO08297.1 - 0.098 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDO08297.1 - 0.11 12.5 0.1 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_M29 PF02073.10 EDO08297.1 - 0.12 11.1 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) AAA_5 PF07728.9 EDO08297.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Pkinase PF00069.20 EDO08298.1 - 4.4e-36 124.3 0.0 2.3e-18 66.2 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO08298.1 - 3.1e-09 36.2 0.0 0.0019 17.3 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase HSP90 PF00183.13 EDO08299.1 - 2.2e-128 429.0 11.9 1.6e-120 403.0 3.7 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 EDO08299.1 - 1.2e-13 50.9 0.1 2.7e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDO08299.1 - 1.8e-08 34.0 0.1 3.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RNA_pol_Rpb1_5 PF04998.12 EDO08301.1 - 3.2e-91 305.4 0.2 5.2e-91 304.7 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EDO08301.1 - 8.8e-75 252.0 0.9 1.4e-74 251.4 0.6 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EDO08301.1 - 2.5e-66 222.7 0.0 5.5e-66 221.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EDO08301.1 - 1.1e-32 112.9 0.0 3.9e-32 111.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EDO08301.1 - 6e-29 99.9 0.0 1.5e-28 98.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Gpi16 PF04113.9 EDO08303.1 - 3.2e-17 61.7 0.3 2.3e-08 32.5 0.0 2.4 2 1 0 2 2 2 2 Gpi16 subunit, GPI transamidase component Ribosomal_S15 PF00312.17 EDO08304.1 - 1.4e-15 56.8 0.3 3.7e-15 55.4 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S15 Adaptin_binding PF10199.4 EDO08304.1 - 0.0093 16.2 0.1 0.017 15.3 0.1 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 PsbN PF02468.10 EDO08304.1 - 0.22 11.1 0.6 0.39 10.3 0.4 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Apq12 PF12716.2 EDO08306.1 - 1.2 8.8 14.7 0.092 12.4 4.0 3.0 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis ABC_ATPase PF09818.4 EDO08308.1 - 6.2e-157 522.7 0.0 3.6e-155 516.9 0.0 2.2 1 1 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.1 EDO08308.1 - 0.00024 21.4 0.3 0.00059 20.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain Helicase_C PF00271.26 EDO08311.1 - 4.5e-11 42.4 0.0 9.2e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO08312.1 - 6.7e-13 48.4 0.1 1.2e-12 47.6 0.0 1.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase EF-hand_7 PF13499.1 EDO08313.1 - 5.8e-24 84.0 12.9 9.1e-11 41.7 0.1 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EDO08313.1 - 6.3e-21 72.7 12.9 0.00039 19.6 0.3 5.5 5 0 0 5 5 5 5 EF hand EF-hand_1 PF00036.27 EDO08313.1 - 3.1e-20 69.8 19.1 0.00011 21.1 0.4 5.9 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.1 EDO08313.1 - 1.8e-18 64.7 10.9 0.0017 18.0 0.0 5.7 6 0 0 6 6 6 5 EF-hand domain EF-hand_8 PF13833.1 EDO08313.1 - 4e-07 29.5 17.0 0.27 10.8 1.2 5.7 4 2 1 5 5 5 5 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EDO08313.1 - 0.0053 16.7 7.3 1.5 8.8 0.8 4.2 2 2 2 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EDO08313.1 - 0.27 10.9 3.2 0.65 9.7 0.2 2.7 3 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand Ribosomal_S4e PF00900.15 EDO08314.1 - 4.8e-28 96.6 0.1 1.1e-27 95.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 EDO08314.1 - 1.7e-19 69.3 5.9 3.6e-19 68.3 4.1 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 EDO08314.1 - 1.2e-06 28.0 3.5 2.3e-06 27.0 0.5 2.9 3 0 0 3 3 3 1 KOW motif S4 PF01479.20 EDO08314.1 - 0.00026 20.3 0.0 0.00051 19.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain DUF3857 PF12969.2 EDO08314.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) EF-hand_6 PF13405.1 EDO08315.1 - 5.8e-10 38.2 0.9 1.2e-06 27.8 0.1 3.6 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.1 EDO08315.1 - 7.8e-10 38.7 1.2 2.3e-09 37.2 0.3 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EDO08315.1 - 1.4e-08 33.4 0.3 6e-06 25.1 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EDO08315.1 - 5.1e-05 22.7 3.3 0.0018 17.8 0.3 3.0 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 EDO08315.1 - 0.00035 19.7 0.1 0.0013 18.0 0.1 2.0 1 0 0 1 1 1 1 EF hand Caleosin PF05042.8 EDO08315.1 - 0.079 12.5 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Caleosin related protein Pkinase PF00069.20 EDO08316.1 - 8.6e-45 152.9 0.0 1.1e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO08316.1 - 4.4e-17 62.0 0.0 6.7e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDO08316.1 - 3.3e-08 32.8 0.0 5.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO08316.1 - 0.0026 17.5 0.0 0.0066 16.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDO08316.1 - 0.0032 16.4 0.2 0.027 13.4 0.1 2.0 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 EDO08316.1 - 0.01 14.6 0.1 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Histone PF00125.19 EDO08317.1 - 6.9e-14 51.7 0.1 8.3e-14 51.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDO08317.1 - 0.0002 21.4 0.1 0.00029 20.9 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EDO08317.1 - 0.00073 19.4 0.0 0.00097 19.0 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EDO08317.1 - 0.001 19.0 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EDO08317.1 - 0.0057 15.9 0.0 0.0061 15.8 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EDO08317.1 - 0.03 14.0 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated EF-hand_6 PF13405.1 EDO08318.1 - 9e-06 25.1 0.1 0.0013 18.4 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EDO08318.1 - 3.1e-05 23.5 0.0 0.00084 18.9 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.1 EDO08318.1 - 4e-05 23.6 0.5 0.00052 20.0 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair RAP PF08373.5 EDO08318.1 - 0.00032 20.4 0.2 0.0009 18.9 0.1 1.8 1 0 0 1 1 1 1 RAP domain EF-hand_1 PF00036.27 EDO08318.1 - 0.00037 19.6 0.0 0.0015 17.7 0.0 2.1 2 0 0 2 2 2 1 EF hand zf-rbx1 PF12678.2 EDO08319.1 - 5.8e-33 112.8 14.2 7.2e-33 112.5 9.8 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EDO08319.1 - 1.4e-16 60.0 11.3 2.8e-16 59.1 7.8 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EDO08319.1 - 5.8e-06 26.0 14.9 9.6e-05 22.1 10.3 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDO08319.1 - 0.012 15.3 14.1 0.28 10.8 9.8 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Toxin_18 PF08087.6 EDO08319.1 - 0.016 14.9 0.9 0.033 13.9 0.6 1.7 1 0 0 1 1 1 0 Conotoxin O-superfamily zf-C3HC4_3 PF13920.1 EDO08319.1 - 0.021 14.5 12.2 3.2 7.5 8.5 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO08319.1 - 0.16 11.7 13.5 1.9 8.2 9.4 2.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EDO08319.1 - 0.18 11.5 6.9 0.22 11.2 1.5 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EDO08319.1 - 0.21 11.6 13.7 0.31 11.1 6.5 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 EDO08319.1 - 0.62 10.0 11.4 7.2 6.6 7.9 2.1 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 EDO08319.1 - 1.7 8.6 13.2 11 6.1 9.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EDO08319.1 - 4.3 7.3 10.4 0.58 10.0 0.5 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING WD40 PF00400.27 EDO08320.1 - 2.2e-06 27.3 6.8 0.14 12.0 0.2 5.3 5 1 0 5 5 5 3 WD domain, G-beta repeat PD40 PF07676.7 EDO08320.1 - 0.019 14.5 0.8 6.4 6.5 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat E1-E2_ATPase PF00122.15 EDO08321.1 - 9.8e-14 50.9 5.7 1.5e-12 47.0 0.0 3.7 4 0 0 4 4 4 1 E1-E2 ATPase HAD PF12710.2 EDO08321.1 - 1.8e-07 31.5 0.2 9.8e-07 29.1 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO08321.1 - 1e-06 29.3 0.0 0.015 15.6 0.0 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDO08321.1 - 9.6e-05 22.2 0.0 0.00066 19.5 0.0 2.3 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDO08321.1 - 0.058 12.9 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1682 PF07946.9 EDO08322.1 - 9.1e-55 185.7 3.7 1.2e-54 185.3 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) HCNGP PF07818.8 EDO08323.1 - 4e-19 68.4 3.4 4e-19 68.4 2.4 1.5 1 1 1 2 2 2 1 HCNGP-like protein WH1 PF00568.18 EDO08324.1 - 0.013 15.2 0.1 0.042 13.5 0.0 1.9 3 0 0 3 3 3 0 WH1 domain DUF2198 PF09964.4 EDO08324.1 - 0.13 12.0 3.6 0.31 10.8 2.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2198) DUF3611 PF12263.3 EDO08324.1 - 0.76 9.1 10.7 0.028 13.8 1.4 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3611) Tetraspannin PF00335.15 EDO08324.1 - 7.6 5.7 18.5 27 3.9 12.7 2.0 1 1 0 1 1 1 0 Tetraspanin family WD40 PF00400.27 EDO08325.1 - 2.2e-53 176.3 20.6 1e-08 34.7 1.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EDO08325.1 - 9.9e-05 21.2 0.8 0.042 12.5 0.0 2.8 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 EDO08325.1 - 0.0054 14.9 7.2 0.79 7.7 0.1 4.0 2 2 2 4 4 4 4 Nucleoporin Nup120/160 FAT PF02259.18 EDO08326.1 - 2.1e-22 79.5 0.5 2.4e-21 76.1 0.1 2.5 2 0 0 2 2 2 1 FAT domain Peptidase_C2 PF00648.16 EDO08327.1 - 3.5e-27 95.2 0.0 2.6e-25 89.0 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.17 EDO08327.1 - 8.2e-18 64.4 1.7 4.4e-15 55.5 0.2 3.5 2 2 0 2 2 2 2 Calpain large subunit, domain III TIP49 PF06068.8 EDO08328.1 - 1.8e-165 550.5 0.1 2.1e-165 550.3 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EDO08328.1 - 1.1e-10 41.8 0.0 1.1e-08 35.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EDO08328.1 - 4e-10 40.0 1.3 1.1e-06 28.9 0.1 3.4 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDO08328.1 - 6.9e-07 28.5 1.4 2.3e-05 23.5 0.0 2.9 4 0 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EDO08328.1 - 3e-06 27.3 0.9 0.0072 16.4 0.0 2.9 3 1 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 EDO08328.1 - 9.3e-05 21.9 0.1 0.032 13.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.22 EDO08328.1 - 0.00011 22.4 0.1 0.00019 21.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 EDO08328.1 - 0.00014 21.5 0.1 0.0078 15.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EDO08328.1 - 0.00055 19.3 0.1 0.0026 17.1 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 EDO08328.1 - 0.00059 19.7 0.1 0.002 17.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDO08328.1 - 0.00065 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO08328.1 - 0.00072 19.2 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EDO08328.1 - 0.0015 17.7 0.3 0.01 14.9 0.1 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EDO08328.1 - 0.003 16.7 0.0 0.0052 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EDO08328.1 - 0.0032 17.1 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 EDO08328.1 - 0.0035 18.1 0.0 0.013 16.3 0.0 1.9 1 1 1 2 2 1 1 AAA domain DNA_pol3_delta2 PF13177.1 EDO08328.1 - 0.0052 16.4 0.4 0.025 14.2 0.0 2.2 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_32 PF13654.1 EDO08328.1 - 0.0057 15.3 0.0 0.0094 14.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO08328.1 - 0.0059 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDO08328.1 - 0.0059 16.5 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EDO08328.1 - 0.0089 14.9 0.0 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EDO08328.1 - 0.011 15.1 0.1 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.11 EDO08328.1 - 0.015 14.5 0.1 0.043 13.0 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein DnaB_C PF03796.10 EDO08328.1 - 0.017 13.9 0.1 0.026 13.3 0.1 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.17 EDO08328.1 - 0.026 14.7 0.0 0.071 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EDO08328.1 - 0.038 13.7 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EDO08328.1 - 0.039 13.9 0.0 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.10 EDO08328.1 - 0.047 13.5 0.1 0.091 12.5 0.1 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EDO08328.1 - 0.051 13.0 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 EDO08328.1 - 0.056 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_2 PF07724.9 EDO08328.1 - 0.062 13.2 0.1 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) APS_kinase PF01583.15 EDO08328.1 - 0.085 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase VESA1_N PF12785.2 EDO08329.1 - 2.7e-218 725.5 22.3 2.7e-218 725.5 15.4 2.6 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 Prominin PF05478.6 EDO08329.1 - 0.012 13.1 0.4 0.029 11.9 0.3 1.5 1 0 0 1 1 1 0 Prominin Dehydrin PF00257.14 EDO08329.1 - 0.022 15.0 9.2 0.068 13.4 4.9 2.6 2 0 0 2 2 2 0 Dehydrin COG2 PF06148.6 EDO08329.1 - 0.14 11.9 4.9 3.8 7.3 0.4 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 EDO08329.1 - 1.9 8.2 9.6 3.2 7.5 1.0 2.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 EDO08329.1 - 2.3 8.0 5.8 6.4 6.6 0.3 3.4 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus VESA1_N PF12785.2 EDO08330.1 - 2.3e-24 86.2 30.0 2.7e-19 69.4 16.0 4.2 1 1 1 2 2 2 2 Variant erythrocyte surface antigen-1 VESA1_N PF12785.2 EDO08332.1 - 4.7e-224 744.5 19.5 4.7e-224 744.5 13.5 2.6 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 CENP-K PF11802.3 EDO08332.1 - 0.29 10.3 1.6 0.58 9.3 1.1 1.4 1 0 0 1 1 1 0 Centromere-associated protein K VESA1_N PF12785.2 EDO08333.1 - 7.1e-219 727.4 17.9 7.1e-219 727.4 12.4 2.2 2 0 0 2 2 2 1 Variant erythrocyte surface antigen-1 F-box-like_2 PF13013.1 EDO08334.1 - 1.4e-06 28.0 0.1 3.2e-05 23.6 0.0 2.3 1 1 1 2 2 2 2 F-box-like domain TatD_DNase PF01026.16 EDO08335.1 - 0.093 11.9 0.0 0.093 11.9 0.0 1.0 1 0 0 1 1 1 0 TatD related DNase DUF1320 PF07030.7 EDO08336.1 - 0.086 12.5 0.1 3.8 7.2 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1320) RtcB PF01139.12 EDO08337.1 - 4.4e-116 388.3 0.1 5.1e-116 388.1 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Ligase_CoA PF00549.14 EDO08338.1 - 1.6e-23 83.0 0.2 2.6e-23 82.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 EDO08338.1 - 2.3e-23 82.4 0.6 8.8e-23 80.6 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 EDO08338.1 - 1e-10 41.3 0.0 1.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EDO08338.1 - 0.0087 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 EDO08338.1 - 0.023 15.2 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pkinase PF00069.20 EDO08339.1 - 6.9e-63 212.2 0.2 8.3e-63 211.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO08339.1 - 1.1e-23 83.6 0.0 1.5e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO08339.1 - 2.2e-08 34.1 0.0 3.6e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDO08339.1 - 0.012 15.1 0.1 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EDO08339.1 - 0.017 14.2 0.1 0.029 13.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SCO1-SenC PF02630.9 EDO08339.1 - 0.032 13.8 0.6 0.054 13.1 0.4 1.3 1 0 0 1 1 1 0 SCO1/SenC Kinase-like PF14531.1 EDO08339.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like HSP70 PF00012.15 EDO08340.1 - 9.3e-246 816.4 14.0 1.1e-245 816.2 9.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO08340.1 - 2.2e-20 72.5 4.8 8.2e-20 70.6 1.8 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EDO08340.1 - 0.039 13.5 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EDO08340.1 - 0.091 12.6 16.4 2.4 8.0 2.0 5.0 3 2 0 3 3 3 0 Cell division protein FtsA DUF615 PF04751.9 EDO08340.1 - 2 8.0 8.9 0.23 11.1 1.6 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF615) Hydantoinase_A PF01968.13 EDO08340.1 - 2.6 7.0 12.8 0.31 10.0 0.4 3.4 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase DUF1712 PF08217.6 EDO08341.1 - 3.9e-11 41.9 9.2 5e-08 31.6 3.3 2.3 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) TPR_11 PF13414.1 EDO08342.1 - 1.5e-21 75.7 9.7 3e-15 55.6 0.6 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EDO08342.1 - 4.2e-07 29.2 7.4 4.4e-05 22.8 0.0 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDO08342.1 - 4.4e-05 23.3 2.1 0.22 11.7 0.0 3.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO08342.1 - 0.00019 21.1 5.1 0.0037 17.0 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF357 PF04010.8 EDO08342.1 - 0.00074 19.1 2.5 0.46 10.2 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF357) TPR_14 PF13428.1 EDO08342.1 - 0.0033 17.9 0.1 0.13 12.9 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF2118 PF09891.4 EDO08342.1 - 0.013 15.2 2.0 0.02 14.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) L27 PF02828.11 EDO08342.1 - 0.037 13.7 0.8 0.35 10.6 0.1 2.3 2 0 0 2 2 2 0 L27 domain DUF4284 PF14112.1 EDO08342.1 - 0.07 13.6 1.1 0.43 11.0 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4284) TPR_8 PF13181.1 EDO08342.1 - 0.071 12.9 4.5 8 6.4 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO08342.1 - 0.086 12.7 8.6 4.5 7.2 0.3 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat BSD PF03909.12 EDO08342.1 - 0.12 12.1 0.7 1 9.1 0.0 2.5 1 1 1 2 2 2 0 BSD domain TPR_20 PF14561.1 EDO08342.1 - 0.31 11.1 3.7 3.9 7.6 0.0 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDO08342.1 - 0.31 11.7 4.3 1.1 9.9 0.3 2.6 2 1 1 3 3 2 0 Tetratricopeptide repeat Gly_radical PF01228.16 EDO08343.1 - 0.075 13.3 0.1 0.4 11.0 0.0 1.8 1 1 1 2 2 2 0 Glycine radical DnaJ PF00226.26 EDO08344.1 - 6.6e-24 83.4 2.2 1.1e-23 82.6 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.15 EDO08344.1 - 1.3e-13 50.5 0.9 2.4e-12 46.4 0.2 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.1 EDO08344.1 - 2.3e-06 27.5 0.2 2.3e-06 27.5 0.1 1.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EDO08344.1 - 0.00082 19.1 0.3 0.0021 17.7 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin domain Glutaredoxin PF00462.19 EDO08344.1 - 0.0087 16.0 1.0 0.03 14.3 0.3 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_8 PF13905.1 EDO08344.1 - 0.053 13.6 0.7 1.2 9.2 0.5 3.2 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.1 EDO08344.1 - 0.11 12.6 5.5 3.2 7.9 1.2 3.3 3 1 0 3 3 3 0 Thioredoxin-like domain AhpC-TSA PF00578.16 EDO08344.1 - 0.12 12.0 1.2 0.77 9.4 0.1 2.6 3 0 0 3 3 3 0 AhpC/TSA family Acetyltransf_1 PF00583.19 EDO08345.1 - 2.1e-11 43.6 0.0 3.9e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO08345.1 - 1.1e-07 31.8 0.0 2.8e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EDO08345.1 - 1.3e-05 25.1 0.1 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDO08345.1 - 0.0021 18.2 0.0 0.0048 17.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDO08345.1 - 0.0079 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EDO08345.1 - 0.067 12.5 0.0 0.18 11.1 0.0 1.7 1 1 0 1 1 1 0 GNAT acetyltransferase 2 His_Phos_1 PF00300.17 EDO08346.1 - 3.5e-42 144.1 0.0 8.9e-42 142.8 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Exc PF07825.6 EDO08346.1 - 0.099 12.4 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Excisionase-like protein Abhydrolase_5 PF12695.2 EDO08347.1 - 6.6e-17 61.6 0.0 8.3e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO08347.1 - 1.2e-12 48.2 0.0 2.9e-06 27.3 0.0 3.0 2 1 1 3 3 3 3 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO08347.1 - 1.5e-09 37.7 0.0 3.5e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EDO08347.1 - 0.0047 16.5 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase Peptidase_S9 PF00326.16 EDO08347.1 - 0.031 13.5 0.0 0.1 11.7 0.0 2.0 2 1 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.8 EDO08347.1 - 0.077 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 EDO08347.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase NPDC1 PF06809.6 EDO08348.1 - 0.14 10.9 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) Sel1 PF08238.7 EDO08350.1 - 1.3e-21 76.5 23.8 4.5e-06 27.1 0.0 9.8 11 0 0 11 11 11 7 Sel1 repeat TPR_16 PF13432.1 EDO08350.1 - 0.00061 20.3 12.9 19 6.1 0.2 7.0 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDO08350.1 - 0.0025 17.4 6.0 24 4.6 0.0 5.9 5 1 2 7 7 7 2 TPR repeat TPR_12 PF13424.1 EDO08350.1 - 0.11 12.5 9.5 1.4 8.9 0.0 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat Tom7 PF08038.7 EDO08350.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 TOM7 family SART-1 PF03343.8 EDO08352.1 - 7.9e-85 285.4 15.9 6.2e-60 203.2 6.6 2.9 1 1 1 2 2 2 2 SART-1 family BSD PF03909.12 EDO08353.1 - 2.5e-11 43.1 0.1 4.8e-06 26.2 0.0 2.7 2 0 0 2 2 2 2 BSD domain ApoC-I PF04691.7 EDO08353.1 - 0.099 12.3 0.1 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) eIF3g PF12353.3 EDO08354.1 - 0.016 15.1 3.0 0.044 13.7 2.1 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G TUDOR PF00567.19 EDO08354.1 - 0.018 14.8 5.7 0.22 11.3 0.3 3.3 1 1 3 4 4 4 0 Tudor domain SH3_1 PF00018.23 EDO08354.1 - 0.27 10.6 1.3 1.4 8.3 0.0 2.8 4 0 0 4 4 4 0 SH3 domain Enolase_C PF00113.17 EDO08355.1 - 1.5e-151 503.4 0.2 1.8e-151 503.1 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EDO08355.1 - 4.9e-53 178.5 0.1 8e-53 177.8 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 EDO08355.1 - 6.7e-06 25.2 0.2 1.1e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 EDO08355.1 - 0.037 14.0 0.1 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Enolase C-terminal domain-like B-block_TFIIIC PF04182.7 EDO08357.1 - 0.0025 17.6 0.0 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC Maf PF02545.9 EDO08359.1 - 1e-29 103.0 0.0 1.9e-29 102.2 0.0 1.4 1 1 0 1 1 1 1 Maf-like protein 2-Hacid_dh PF00389.25 EDO08359.1 - 0.044 13.2 0.0 0.061 12.7 0.0 1.3 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain eRF1_1 PF03463.10 EDO08360.1 - 5.3e-26 90.7 0.2 1.4e-25 89.3 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EDO08360.1 - 5.1e-15 55.7 1.1 1.6e-14 54.0 0.1 2.3 3 0 0 3 3 3 1 eRF1 domain 3 eRF1_2 PF03464.10 EDO08360.1 - 2.5e-14 53.7 0.1 7.9e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 2 Pam16 PF03656.8 EDO08361.1 - 2.9e-10 40.0 0.0 3.1e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.26 EDO08361.1 - 9.6e-08 31.6 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain E1_dh PF00676.15 EDO08361.1 - 0.049 12.3 0.0 0.051 12.2 0.0 1.1 1 0 0 1 1 1 0 Dehydrogenase E1 component DUF1279 PF06916.8 EDO08362.1 - 1.1e-07 31.9 0.2 1.1e-07 31.9 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) MotA_ExbB PF01618.11 EDO08363.1 - 0.036 13.6 0.8 0.2 11.2 0.4 2.3 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family FPL PF09758.4 EDO08364.1 - 5.1e-32 110.6 3.9 1.1e-31 109.5 2.7 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3395 PF11875.3 EDO08365.1 - 1.5e-21 76.5 0.0 2.6e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EDO08365.1 - 3.4e-15 55.5 0.3 6.2e-15 54.6 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1279 PF06916.8 EDO08365.1 - 0.0071 16.6 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) PET PF06297.9 EDO08365.1 - 0.046 13.3 0.1 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 PET Domain Ribosomal_L27 PF01016.14 EDO08366.1 - 7.8e-12 44.8 0.6 1.8e-06 27.6 0.1 2.2 1 1 1 2 2 2 2 Ribosomal L27 protein Pinin_SDK_memA PF04696.8 EDO08368.1 - 2.4e-08 33.6 3.0 2.4e-08 33.6 2.1 1.6 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Syntaxin PF00804.20 EDO08368.1 - 0.017 15.2 2.1 0.017 15.2 1.5 1.8 2 0 0 2 2 2 0 Syntaxin Uds1 PF15456.1 EDO08368.1 - 0.025 14.5 11.7 0.64 10.0 0.2 2.3 2 0 0 2 2 2 0 Up-regulated During Septation DASH_Spc19 PF08287.6 EDO08368.1 - 0.056 13.0 0.4 0.056 13.0 0.3 2.4 2 1 0 2 2 2 0 Spc19 CASP_C PF08172.7 EDO08368.1 - 0.063 12.2 10.6 0.061 12.3 0.8 2.2 1 1 0 2 2 2 0 CASP C terminal DUF775 PF05603.7 EDO08368.1 - 0.072 12.6 0.5 0.11 12.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Prominin PF05478.6 EDO08368.1 - 0.13 9.7 2.1 0.16 9.4 1.5 1.1 1 0 0 1 1 1 0 Prominin DUF479 PF04336.7 EDO08368.1 - 0.16 12.0 3.1 0.14 12.2 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF479 CDC37_N PF03234.9 EDO08368.1 - 0.19 12.0 8.5 0.76 10.0 5.6 1.9 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Seryl_tRNA_N PF02403.17 EDO08368.1 - 0.27 11.2 8.7 0.11 12.4 3.9 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fmp27_WPPW PF10359.4 EDO08368.1 - 0.4 9.0 6.5 0.94 7.8 1.4 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Prefoldin PF02996.12 EDO08368.1 - 0.56 9.8 7.6 13 5.4 3.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit OmpH PF03938.9 EDO08368.1 - 0.68 9.8 11.4 0.98 9.3 7.9 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin_2 PF14523.1 EDO08368.1 - 0.83 9.7 8.8 1.7 8.7 3.6 2.7 1 1 1 2 2 2 0 Syntaxin-like protein Tropomyosin_1 PF12718.2 EDO08368.1 - 0.84 9.4 14.0 5.4 6.8 0.2 2.4 2 1 0 2 2 2 0 Tropomyosin like Atg14 PF10186.4 EDO08368.1 - 1.1 8.1 12.5 0.55 9.1 4.4 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PGC7_Stella PF15549.1 EDO08368.1 - 1.4 8.8 8.0 0.53 10.2 2.0 2.7 1 1 1 2 2 2 0 PGC7/Stella/Dppa3 domain DUF4200 PF13863.1 EDO08368.1 - 3.4 7.6 13.0 2.2 8.2 3.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) eIF3_p135 PF12807.2 EDO08369.1 - 7.1e-09 35.8 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.1 EDO08369.1 - 0.0056 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria TPR_2 PF07719.12 EDO08369.1 - 0.047 13.6 0.2 0.99 9.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.24 EDO08371.1 - 1.5e-14 53.8 0.0 3e-14 52.8 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDO08371.1 - 0.018 14.8 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ribosomal_60s PF00428.14 EDO08372.1 - 1.5e-24 86.2 9.8 1.9e-24 85.8 6.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytochrom_C PF00034.16 EDO08373.1 - 1.4e-07 32.2 0.0 2.5e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EDO08373.1 - 2.1e-05 24.5 1.2 9.6e-05 22.4 0.8 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C1 PF02167.10 EDO08373.1 - 0.00079 19.1 0.1 0.0015 18.2 0.1 1.4 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrom_C550 PF14495.1 EDO08373.1 - 0.0014 18.0 3.0 0.027 13.9 0.4 2.4 1 1 0 2 2 2 2 Cytochrome c-550 domain Haem_bd PF14376.1 EDO08373.1 - 0.0077 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Haem-binding domain ATP-synt_ab PF00006.20 EDO08375.1 - 1.3e-99 332.0 0.0 1.9e-99 331.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDO08375.1 - 1e-17 64.5 0.0 2.1e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDO08375.1 - 8.1e-16 58.0 1.5 2.5e-15 56.4 0.2 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_31 PF13614.1 EDO08375.1 - 0.062 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain GYF PF02213.11 EDO08376.1 - 0.0003 20.3 0.6 0.00067 19.1 0.4 1.6 1 0 0 1 1 1 1 GYF domain AAA_11 PF13086.1 EDO08377.1 - 7.2e-71 238.5 0.0 1.9e-70 237.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EDO08377.1 - 2.8e-63 212.9 0.0 4.3e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO08377.1 - 1.7e-12 46.9 0.4 4.5e-08 32.7 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_30 PF13604.1 EDO08377.1 - 1.9e-07 30.8 0.0 0.0011 18.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 EDO08377.1 - 8.8e-07 28.6 0.1 0.0007 19.1 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EDO08377.1 - 0.0034 17.5 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDO08377.1 - 0.0037 16.6 0.0 0.0066 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EDO08377.1 - 0.006 15.5 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EDO08377.1 - 0.0075 16.2 0.0 0.027 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain UvrD-helicase PF00580.16 EDO08377.1 - 0.01 15.1 0.0 0.4 9.9 0.0 2.6 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EDO08377.1 - 0.012 15.1 0.0 0.049 13.1 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase Helicase_RecD PF05127.9 EDO08377.1 - 0.014 15.0 0.0 0.54 9.8 0.0 3.0 2 1 0 2 2 2 0 Helicase DUF3477 PF11963.3 EDO08377.1 - 0.014 14.4 0.2 0.024 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3477) AAA PF00004.24 EDO08377.1 - 0.039 14.1 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EDO08377.1 - 0.04 14.2 0.0 0.082 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EDO08377.1 - 0.11 11.4 0.0 0.62 8.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EDO08377.1 - 0.12 12.5 0.0 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ResIII PF04851.10 EDO08377.1 - 0.19 11.5 0.0 0.82 9.4 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Acetyltransf_1 PF00583.19 EDO08378.1 - 7.5e-07 29.0 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO08378.1 - 4e-06 26.9 0.0 6.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO08378.1 - 0.0051 16.9 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CheR_N PF03705.10 EDO08378.1 - 0.044 13.1 0.3 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain FR47 PF08445.5 EDO08378.1 - 0.057 13.1 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_9 PF13527.1 EDO08378.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SNARE PF05739.14 EDO08379.1 - 0.0029 17.2 0.3 0.0029 17.2 0.2 1.9 2 0 0 2 2 2 1 SNARE domain DUF1359 PF07097.6 EDO08379.1 - 0.046 13.7 1.4 20 5.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1359) DASH_Duo1 PF08651.5 EDO08379.1 - 0.36 10.4 3.0 8.5 6.0 0.0 3.2 2 1 1 3 3 3 0 DASH complex subunit Duo1 E1_dh PF00676.15 EDO08380.1 - 4.1e-81 271.9 0.1 5e-81 271.6 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component MRP-S28 PF10213.4 EDO08382.1 - 2.2e-10 40.6 0.0 4.4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein CedA PF10729.4 EDO08383.1 - 0.034 13.6 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 Cell division activator CedA RRM_1 PF00076.17 EDO08385.1 - 1.3e-10 40.7 0.0 2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO08385.1 - 4.4e-07 29.7 0.0 6.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDO08385.1 - 0.0087 15.8 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.1 EDO08385.1 - 0.0095 15.7 0.0 0.014 15.1 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDO08385.1 - 0.06 13.1 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 TraL PF07178.6 EDO08386.1 - 0.051 13.6 4.0 0.046 13.7 1.1 2.3 1 1 0 1 1 1 0 TraL protein DUF3815 PF12821.2 EDO08386.1 - 0.14 12.0 2.7 2.5 8.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3815) DEAD PF00270.24 EDO08387.1 - 1.2e-31 109.4 1.3 2.2e-31 108.6 0.9 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO08387.1 - 1e-18 66.9 0.1 2.7e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDO08387.1 - 0.00011 21.1 0.1 0.00024 20.0 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain YEATS PF03366.11 EDO08388.1 - 2.3e-28 97.7 0.3 3.9e-28 96.9 0.2 1.4 1 0 0 1 1 1 1 YEATS family V_ATPase_I PF01496.14 EDO08390.1 - 3.1e-159 531.3 6.8 3.7e-159 531.0 4.7 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family MMR_HSR1 PF01926.18 EDO08391.1 - 3.5e-18 65.6 0.0 6.6e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.8 EDO08391.1 - 6.3e-06 25.2 0.0 1.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 EDO08391.1 - 3.9e-05 22.9 0.1 0.00011 21.5 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EDO08391.1 - 0.00013 21.4 0.1 0.0027 17.1 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EDO08391.1 - 0.001 18.9 0.1 0.81 9.4 0.1 2.6 1 1 1 2 2 2 2 Dynamin family Septin PF00735.13 EDO08391.1 - 0.0035 16.4 0.0 0.0082 15.1 0.0 1.6 1 0 0 1 1 1 1 Septin Miro PF08477.8 EDO08391.1 - 0.0048 17.3 0.1 0.016 15.7 0.1 2.0 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EDO08391.1 - 0.0065 15.6 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EDO08391.1 - 0.022 13.8 0.1 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 AIG1 family MobB PF03205.9 EDO08391.1 - 0.037 13.7 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EDO08391.1 - 0.053 13.0 4.9 1.6 8.1 0.2 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 EDO08391.1 - 0.17 11.4 0.1 0.47 10.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ribosomal_L3 PF00297.17 EDO08392.1 - 1.3e-21 77.1 0.9 8.4e-21 74.5 0.7 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 RRM_6 PF14259.1 EDO08393.1 - 0.0025 17.7 0.1 3.2 7.8 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Plant_all_beta PF10532.4 EDO08393.1 - 0.058 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Plant specific N-all beta domain L1R_F9L PF02442.12 EDO08393.1 - 0.11 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses Nucleoporin2 PF04096.9 EDO08394.1 - 4.6e-38 130.2 0.0 8.1e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EDO08394.1 - 4.8e-33 113.7 291.5 2.1e-11 44.0 34.4 8.3 2 2 4 6 6 6 5 Nucleoporin FG repeat region DUF1347 PF07079.6 EDO08394.1 - 0.68 8.0 0.4 1 7.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) Ribosomal_S21e PF01249.13 EDO08395.1 - 1.2e-32 111.6 0.0 1.3e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Img2 PF05046.9 EDO08396.1 - 1.2e-18 67.1 0.0 1.9e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Peptidase_M24 PF00557.19 EDO08397.1 - 6.8e-40 136.8 0.0 1.1e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EDO08397.1 - 1.8e-15 57.5 0.0 7.2e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain eIF-3c_N PF05470.7 EDO08398.1 - 1.7e-97 326.9 29.9 1.8e-71 240.9 1.2 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EDO08398.1 - 1.5e-11 44.5 0.4 2.8e-10 40.4 0.0 3.0 3 0 0 3 3 3 1 PCI domain FAT PF02259.18 EDO08398.1 - 0.0038 16.2 0.2 0.0072 15.3 0.1 1.5 1 0 0 1 1 1 1 FAT domain DUF2089 PF09862.4 EDO08398.1 - 0.01 15.5 0.6 0.024 14.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) FeoC PF09012.5 EDO08398.1 - 0.035 13.8 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 FeoC like transcriptional regulator DUF2201_N PF13203.1 EDO08398.1 - 0.78 8.8 15.4 0.069 12.3 5.5 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF2457 PF10446.4 EDO08398.1 - 1.2 7.8 33.0 2.8 6.5 22.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) tRNA-synt_1 PF00133.17 EDO08399.1 - 8.5e-183 608.6 0.0 5.9e-182 605.8 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EDO08399.1 - 2.6e-40 137.6 0.0 5.2e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EDO08399.1 - 2.8e-18 65.7 0.2 2.7e-08 32.8 0.0 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EDO08399.1 - 1.9e-08 33.8 0.5 2.6e-07 30.1 0.0 2.6 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 EDO08399.1 - 9.6e-06 25.5 1.8 9.6e-06 25.5 1.3 1.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1b PF00579.20 EDO08399.1 - 0.0067 15.5 0.2 0.19 10.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) tRNA-synt_1c PF00749.16 EDO08399.1 - 0.063 11.9 0.0 0.25 9.9 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain UPF0020 PF01170.13 EDO08401.1 - 0.013 15.0 0.0 0.059 12.9 0.0 1.9 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Rad9 PF04139.8 EDO08402.1 - 3.2e-16 59.2 0.0 4.7e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Rad9 PCNA_N PF00705.13 EDO08402.1 - 0.013 15.0 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain NESP55 PF06390.7 EDO08402.1 - 0.049 12.9 3.7 0.07 12.4 2.5 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) RimM PF01782.13 EDO08403.1 - 1.3e-15 57.1 0.0 2.4e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 RimM N-terminal domain zf-C2H2_6 PF13912.1 EDO08403.1 - 0.035 14.0 0.3 0.064 13.1 0.2 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger APO_RNA-bind PF05634.6 EDO08403.1 - 0.051 12.7 2.2 0.42 9.7 0.0 2.6 2 1 0 2 2 2 0 APO RNA-binding zf-met PF12874.2 EDO08403.1 - 0.053 13.7 0.9 0.097 12.9 0.6 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EDO08403.1 - 0.11 12.8 0.2 0.29 11.5 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Cyclin_C PF02984.14 EDO08405.1 - 0.0052 16.7 1.1 0.12 12.2 0.1 2.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 EDO08405.1 - 0.0066 16.0 0.1 2.1 7.9 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Ribosomal_S2 PF00318.15 EDO08406.1 - 5.6e-43 146.6 0.3 5.7e-21 74.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 PPI_Ypi1 PF07491.6 EDO08407.1 - 5.5e-21 73.9 1.4 7e-21 73.6 1.0 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor Surp PF01805.15 EDO08409.1 - 2e-14 52.9 0.6 6.6e-14 51.2 0.0 2.2 3 0 0 3 3 3 1 Surp module RRM_1 PF00076.17 EDO08409.1 - 4.4e-10 39.0 0.0 1.2e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO08409.1 - 5.3e-05 23.1 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO08409.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EDO08409.1 - 0.45 10.8 4.3 0.21 11.8 0.1 2.6 3 1 0 3 3 3 0 RNA polymerase II-binding domain. Ribosomal_S27 PF01599.14 EDO08410.1 - 4e-22 77.7 3.5 9.2e-22 76.6 2.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 EDO08410.1 - 0.0025 17.1 0.0 0.017 14.5 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family zf-CGNR PF11706.3 EDO08410.1 - 0.014 14.8 1.3 0.014 14.8 0.9 1.6 2 0 0 2 2 2 0 CGNR zinc finger UBX PF00789.15 EDO08410.1 - 0.11 12.6 0.0 19 5.3 0.0 2.2 2 0 0 2 2 2 0 UBX domain Fer2_3 PF13085.1 EDO08410.1 - 0.16 11.7 1.3 0.28 11.0 0.9 1.5 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain WW PF00397.21 EDO08411.1 - 0.00023 20.9 1.6 0.00095 18.9 0.0 2.4 2 0 0 2 2 2 1 WW domain Myticin-prepro PF10690.4 EDO08411.1 - 0.13 12.2 0.9 4.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel DUF1700 PF08006.6 EDO08411.1 - 0.27 10.5 0.8 0.45 9.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) zf-U1 PF06220.7 EDO08411.1 - 0.28 10.7 3.6 0.75 9.4 2.5 1.8 1 1 0 1 1 1 0 U1 zinc finger zf-C2H2_jaz PF12171.3 EDO08411.1 - 1.9 8.7 5.1 5 7.4 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DivIC PF04977.10 EDO08411.1 - 9.2 5.8 7.7 0.83 9.1 0.6 2.6 2 1 0 2 2 2 0 Septum formation initiator SAC3_GANP PF03399.11 EDO08413.1 - 9.2e-22 77.5 0.9 2.1e-21 76.4 0.6 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Nucleoporin_FG PF13634.1 EDO08413.1 - 0.61 10.3 153.9 0.33 11.1 21.3 6.3 1 1 4 5 5 5 0 Nucleoporin FG repeat region DCP1 PF06058.8 EDO08414.1 - 4.3e-30 104.2 0.3 2e-29 102.1 0.1 1.9 2 0 0 2 2 2 1 Dcp1-like decapping family TFIIA PF03153.8 EDO08414.1 - 1.4 8.7 4.6 2.1 8.1 3.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIGA PF08288.7 EDO08416.1 - 5e-33 113.3 0.4 1.3e-32 111.9 0.3 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EDO08416.1 - 6.6e-26 90.7 0.0 9.3e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EDO08416.1 - 3.4e-12 46.6 0.0 7.3e-12 45.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EDO08416.1 - 1.5e-07 31.6 0.0 2.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EDO08416.1 - 7.5e-07 29.0 0.0 2.3e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 EDO08416.1 - 0.0011 19.1 0.0 0.0051 17.0 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EDO08416.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like NOSIC PF08060.8 EDO08416.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 NOSIC (NUC001) domain DUF547 PF04784.9 EDO08417.1 - 0.0036 17.1 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 WD40 PF00400.27 EDO08417.1 - 0.054 13.4 3.6 0.13 12.2 0.2 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat Macoilin PF09726.4 EDO08417.1 - 6.6 4.8 7.9 10 4.2 5.4 1.2 1 0 0 1 1 1 0 Transmembrane protein PCI PF01399.22 EDO08418.1 - 9.2e-18 64.4 1.2 9.2e-18 64.4 0.9 2.4 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EDO08418.1 - 0.048 13.4 1.2 0.084 12.6 0.2 1.9 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 SNAP PF14938.1 EDO08418.1 - 0.071 12.2 0.7 0.97 8.5 0.0 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP LRRC37AB_C PF14914.1 EDO08419.1 - 0.065 12.6 0.2 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DER1 PF04511.10 EDO08420.1 - 1.3e-28 99.8 21.8 1.7e-28 99.5 15.1 1.0 1 0 0 1 1 1 1 Der1-like family DUF2627 PF11118.3 EDO08420.1 - 0.023 14.8 1.3 0.023 14.8 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) DUF155 PF02582.9 EDO08421.1 - 1.7e-10 41.0 0.2 2.4e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 RRM_1 PF00076.17 EDO08422.1 - 1.1e-29 101.8 0.6 5.7e-15 54.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO08422.1 - 1.3e-25 89.1 0.2 5.7e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO08422.1 - 7.6e-06 25.6 1.9 0.0091 15.8 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UCH PF00443.24 EDO08423.1 - 1.5e-38 132.4 0.0 3.5e-38 131.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO08423.1 - 8e-08 32.0 0.2 4e-07 29.7 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EDO08423.1 - 2.4e-06 26.8 0.0 9.4e-06 24.9 0.0 2.1 3 0 0 3 3 3 1 Ubiquitin family Thermopsin PF05317.6 EDO08424.1 - 0.00022 20.2 4.2 0.00022 20.2 2.9 1.4 2 0 0 2 2 2 1 Thermopsin DUF4448 PF14610.1 EDO08424.1 - 0.05 13.0 5.2 0.093 12.2 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) GYF PF02213.11 EDO08424.1 - 0.05 13.1 2.0 0.11 12.0 1.4 1.7 1 0 0 1 1 1 0 GYF domain Peptidase_M24 PF00557.19 EDO08425.1 - 1.5e-37 129.1 0.4 1.8e-37 128.9 0.3 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 EF-hand_1 PF00036.27 EDO08426.1 - 1.2e-14 52.3 2.3 4.3e-06 25.6 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EDO08426.1 - 1.9e-13 50.2 1.2 1.5e-06 28.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EDO08426.1 - 8.2e-13 47.0 2.0 2.4e-05 23.8 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EDO08426.1 - 1.1e-10 40.2 0.6 1.8e-05 23.8 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EDO08426.1 - 3.1e-08 33.0 2.0 0.013 15.1 0.2 3.6 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EDO08426.1 - 0.013 15.4 0.1 1.1 9.2 0.0 2.6 2 1 1 3 3 3 0 EF-hand domain UPF0154 PF03672.8 EDO08426.1 - 0.038 13.6 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_10 PF14788.1 EDO08426.1 - 0.084 12.5 0.1 31 4.3 0.0 3.2 3 0 0 3 3 3 0 EF hand KOW PF00467.24 EDO08427.1 - 2.5e-08 33.2 0.6 6.1e-08 32.0 0.4 1.6 1 0 0 1 1 1 1 KOW motif SNF2_N PF00176.18 EDO08428.1 - 1.8e-60 204.2 3.1 4.6e-31 107.7 0.6 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO08428.1 - 4.9e-14 51.9 0.0 1.1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EDO08428.1 - 2e-07 30.6 9.3 2e-07 30.6 6.4 2.3 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 EDO08428.1 - 9.6e-05 22.4 2.6 0.00041 20.3 1.8 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EDO08428.1 - 0.00076 19.1 9.6 0.00076 19.1 6.6 2.6 2 0 0 2 2 1 1 zinc-RING finger domain ResIII PF04851.10 EDO08428.1 - 0.0011 18.8 0.8 0.0041 16.9 0.2 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C2HC_2 PF13913.1 EDO08428.1 - 0.0015 18.1 0.0 0.0049 16.4 0.0 1.8 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C3HC4 PF00097.20 EDO08428.1 - 0.0035 16.9 9.4 0.0035 16.9 6.5 2.9 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDO08428.1 - 0.032 14.0 1.7 0.1 12.4 1.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SAP PF02037.22 EDO08428.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 SAP domain AAA_22 PF13401.1 EDO08428.1 - 0.051 13.7 0.0 0.39 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain zf-C3HC4_2 PF13923.1 EDO08428.1 - 9.9 6.2 21.9 0.016 15.1 6.4 2.9 2 1 1 3 3 2 0 Zinc finger, C3HC4 type (RING finger) DUF1900 PF08954.6 EDO08429.1 - 1.6e-32 111.8 0.0 2.3e-31 108.1 0.0 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) WD40 PF00400.27 EDO08429.1 - 1.7e-15 56.2 6.5 1.5e-06 27.8 0.2 4.8 4 1 0 4 4 4 2 WD domain, G-beta repeat DUF1899 PF08953.6 EDO08429.1 - 0.00011 21.7 0.0 0.00029 20.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Coatomer_WDAD PF04053.9 EDO08429.1 - 0.094 11.4 0.4 0.21 10.3 0.2 1.5 1 1 0 1 1 1 0 Coatomer WD associated region DEAD PF00270.24 EDO08431.1 - 8.1e-42 142.5 0.4 8.1e-42 142.5 0.3 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO08431.1 - 1e-19 70.1 0.0 2.9e-19 68.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain tRNA-synt_1b PF00579.20 EDO08433.1 - 2.3e-52 177.9 0.0 2.7e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pkinase PF00069.20 EDO08434.1 - 4.5e-50 170.2 0.0 7.3e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO08434.1 - 8.4e-29 100.4 0.0 1.6e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO08434.1 - 0.00012 21.1 0.0 0.00018 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Peptidase_C71 PF12386.3 EDO08435.1 - 0.063 12.7 0.9 0.11 11.9 0.6 1.4 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei TSKS PF15358.1 EDO08435.1 - 0.076 11.1 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate DUF221 PF02714.10 EDO08436.1 - 6.9e-10 38.2 0.6 6.9e-10 38.2 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 Vps26 PF03643.10 EDO08437.1 - 2.6e-77 259.2 1.8 4.3e-65 219.2 2.2 2.0 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 TPR_11 PF13414.1 EDO08438.1 - 2.5e-06 27.0 0.1 1e-05 25.0 0.1 2.1 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EDO08438.1 - 0.15 11.6 2.9 1.6 8.4 0.9 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C_2 PF13307.1 EDO08439.1 - 5e-53 179.4 0.1 1.6e-52 177.8 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EDO08439.1 - 4.6e-45 153.1 0.4 1.1e-44 151.9 0.3 1.7 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 EDO08439.1 - 3.8e-06 26.4 0.2 0.0017 17.8 0.1 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EDO08439.1 - 0.00037 20.3 1.0 0.058 13.2 0.2 2.7 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EDO08439.1 - 0.022 14.5 0.0 0.083 12.6 0.0 1.9 1 1 0 1 1 1 0 Part of AAA domain Cwf_Cwc_15 PF04889.7 EDO08440.1 - 9.7 5.8 17.0 5.4 6.6 10.0 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein LsmAD PF06741.8 EDO08441.1 - 2.1e-10 40.5 0.3 2.1e-10 40.5 0.2 2.6 4 0 0 4 4 4 1 LsmAD domain PAM2 PF07145.10 EDO08441.1 - 0.08 12.4 1.9 0.24 10.9 1.3 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region DUF1236 PF06823.7 EDO08441.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1236) MMR_HSR1 PF01926.18 EDO08442.1 - 1.5e-17 63.5 0.0 2.5e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO08442.1 - 1.4e-06 27.7 0.0 0.00019 20.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 EDO08442.1 - 2.3e-05 23.7 0.1 0.002 17.3 0.0 2.9 2 1 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.18 EDO08442.1 - 0.00027 20.7 0.0 0.0076 16.0 0.1 2.2 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 EDO08442.1 - 0.00028 20.3 0.0 0.22 10.9 0.0 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EDO08442.1 - 0.0018 17.7 0.0 0.11 11.9 0.0 2.7 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EDO08442.1 - 0.0044 16.4 0.6 0.67 9.3 0.0 2.7 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.7 EDO08442.1 - 0.0095 15.0 0.0 0.02 14.0 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GBP PF02263.14 EDO08442.1 - 0.02 13.9 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Miro PF08477.8 EDO08442.1 - 0.053 14.0 0.0 1 9.9 0.0 2.4 1 1 0 1 1 1 0 Miro-like protein Ras PF00071.17 EDO08442.1 - 0.054 12.8 0.0 0.64 9.4 0.0 2.3 2 0 0 2 2 2 0 Ras family KH_2 PF07650.12 EDO08442.1 - 0.07 12.6 0.0 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 KH domain RNA_helicase PF00910.17 EDO08442.1 - 0.081 13.0 0.0 0.49 10.5 0.0 2.1 1 1 0 1 1 1 0 RNA helicase Ubiq_cyt_C_chap PF03981.7 EDO08443.1 - 2.4e-08 33.9 1.5 3.3e-08 33.4 1.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone ACDC PF14733.1 EDO08444.1 - 1e-24 86.4 3.9 1.6e-24 85.8 2.7 1.3 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 EDO08444.1 - 2.3e-14 53.2 0.8 5.3e-14 52.1 0.6 1.7 1 0 0 1 1 1 1 AP2 domain Pkinase PF00069.20 EDO08445.1 - 1.6e-41 142.2 0.0 1.2e-39 136.0 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO08445.1 - 1.2e-14 53.9 0.0 1.2e-11 44.1 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Trm112p PF03966.11 EDO08446.1 - 2.7e-10 40.4 0.0 9.5e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Trm112p-like protein zinc_ribbon_4 PF13717.1 EDO08446.1 - 0.054 13.1 0.2 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EDO08446.1 - 0.059 12.9 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DUF2683 PF10884.3 EDO08446.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) PRP38 PF03371.10 EDO08447.1 - 1.1e-46 158.5 0.3 1.6e-46 158.0 0.2 1.2 1 0 0 1 1 1 1 PRP38 family PAPS_reduct PF01507.14 EDO08448.1 - 0.03 14.1 3.9 0.24 11.1 2.7 2.0 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family T2SF PF00482.18 EDO08448.1 - 0.034 14.0 0.6 0.097 12.5 0.1 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F MSC PF09402.5 EDO08448.1 - 0.036 12.7 2.8 0.023 13.4 0.5 1.6 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain Pex24p PF06398.6 EDO08448.1 - 0.12 11.1 0.6 0.18 10.5 0.4 1.5 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF892 PF05974.7 EDO08448.1 - 0.13 12.1 3.1 6.1 6.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF892) HeLo PF14479.1 EDO08448.1 - 0.21 11.3 4.5 0.32 10.7 3.1 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation Spectrin PF00435.16 EDO08448.1 - 0.23 11.7 7.5 1.7 8.9 0.2 2.4 2 1 0 2 2 2 0 Spectrin repeat FliT PF05400.8 EDO08448.1 - 9.5 6.7 8.1 11 6.4 0.2 3.6 2 2 2 4 4 4 0 Flagellar protein FliT Fibrillarin PF01269.12 EDO08449.1 - 2e-108 360.6 0.0 2.4e-108 360.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EDO08449.1 - 0.00019 20.9 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 EDO08449.1 - 0.0029 18.1 0.0 0.0051 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO08449.1 - 0.012 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EDO08449.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LCCL PF03815.14 EDO08450.1 - 1.4e-82 271.7 13.1 1.2e-23 82.9 0.2 5.4 5 0 0 5 5 5 4 LCCL domain SRCR PF00530.13 EDO08450.1 - 9.2e-33 112.5 12.4 1.2e-16 60.8 1.4 3.2 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain PLAT PF01477.18 EDO08450.1 - 6e-15 55.6 0.1 7.8e-12 45.5 0.0 2.6 2 0 0 2 2 2 2 PLAT/LH2 domain Laminin_G_3 PF13385.1 EDO08450.1 - 7.4e-10 39.2 0.0 1.6e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SRCR_2 PF15494.1 EDO08450.1 - 2.2e-08 34.2 2.6 0.00062 19.9 0.6 2.8 2 1 0 2 2 2 2 Scavenger receptor cysteine-rich domain Rxt3 PF08642.5 EDO08450.1 - 8.7e-07 29.1 0.1 0.099 12.8 0.0 3.0 3 0 0 3 3 3 2 Histone deacetylation protein Rxt3 YecR PF13992.1 EDO08450.1 - 0.063 13.4 0.8 0.65 10.2 0.1 2.6 2 0 0 2 2 2 0 YecR-like lipoprotein Radical_SAM PF04055.16 EDO08451.1 - 6.8e-12 45.8 0.0 1.9e-11 44.4 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 EDO08451.1 - 0.0037 17.2 0.0 0.0088 16.0 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3273 PF11677.3 EDO08452.1 - 1.2e-85 286.9 7.5 1.5e-85 286.6 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Metallophos_2 PF12850.2 EDO08454.1 - 1.5e-20 73.6 0.0 1.8e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EDO08454.1 - 0.032 13.6 0.3 0.071 12.4 0.1 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase AAA_2 PF07724.9 EDO08455.1 - 2.1e-47 161.1 0.2 1.5e-46 158.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EDO08455.1 - 1.4e-21 77.0 0.2 9e-10 38.8 0.0 3.6 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO08455.1 - 1.7e-19 69.8 0.1 5.8e-12 45.5 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 EDO08455.1 - 1.6e-16 59.9 0.6 5e-07 29.5 0.1 2.9 2 0 0 2 2 2 2 Clp amino terminal domain ClpB_D2-small PF10431.4 EDO08455.1 - 3.4e-15 55.6 0.2 2.4e-14 52.9 0.1 2.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.1 EDO08455.1 - 4.3e-14 52.7 2.3 4.2e-06 26.9 0.1 4.4 4 2 0 4 4 2 2 AAA domain AAA_16 PF13191.1 EDO08455.1 - 1.1e-09 38.5 0.1 0.029 14.3 0.0 4.1 3 1 1 4 4 3 3 AAA ATPase domain Mg_chelatase PF01078.16 EDO08455.1 - 4e-07 29.4 0.0 0.026 13.6 0.0 3.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EDO08455.1 - 6.2e-07 29.0 0.0 3.9e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 EDO08455.1 - 6.2e-07 28.7 0.1 0.00027 20.1 0.0 3.7 4 0 0 4 4 4 1 Zeta toxin AAA_18 PF13238.1 EDO08455.1 - 1.9e-06 28.2 4.9 0.0024 18.1 0.4 3.6 3 1 0 3 3 2 2 AAA domain DNA_pol3_delta2 PF13177.1 EDO08455.1 - 3.2e-06 26.9 1.4 0.067 12.8 0.0 4.3 3 1 1 4 4 4 2 DNA polymerase III, delta subunit AAA_33 PF13671.1 EDO08455.1 - 1e-05 25.4 0.0 0.24 11.2 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EDO08455.1 - 1.5e-05 24.8 0.6 0.084 12.7 0.0 3.5 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.17 EDO08455.1 - 4.4e-05 23.6 0.2 0.24 11.5 0.0 3.5 3 0 0 3 3 3 1 RNA helicase AAA_17 PF13207.1 EDO08455.1 - 5.5e-05 23.9 0.9 0.028 15.2 0.0 3.8 2 2 1 3 3 2 1 AAA domain RuvB_N PF05496.7 EDO08455.1 - 6.1e-05 22.1 0.0 0.087 11.8 0.0 3.5 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EDO08455.1 - 6.9e-05 22.3 0.1 0.24 10.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_10 PF12846.2 EDO08455.1 - 0.0002 20.9 0.1 0.16 11.3 0.0 3.5 3 0 0 3 3 3 1 AAA-like domain AAA_25 PF13481.1 EDO08455.1 - 0.00023 20.6 0.2 0.12 11.7 0.0 3.1 4 0 0 4 4 2 1 AAA domain MMR_HSR1 PF01926.18 EDO08455.1 - 0.00073 19.4 0.3 1.5 8.7 0.0 3.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EDO08455.1 - 0.00079 19.7 0.2 0.4 10.9 0.0 2.8 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 EDO08455.1 - 0.00093 18.8 0.0 0.018 14.6 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.6 EDO08455.1 - 0.0017 17.9 0.5 0.49 10.0 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 EDO08455.1 - 0.0043 16.3 0.2 0.47 9.6 0.0 3.1 3 0 0 3 3 3 1 Chromatin associated protein KTI12 NTPase_1 PF03266.10 EDO08455.1 - 0.0065 16.2 0.6 2.5 7.7 0.0 3.6 4 0 0 4 4 3 1 NTPase DUF258 PF03193.11 EDO08455.1 - 0.012 14.8 0.0 3.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 EDO08455.1 - 0.014 15.1 0.0 0.25 11.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 EDO08455.1 - 0.02 14.4 0.6 1 8.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain Torsin PF06309.6 EDO08455.1 - 0.021 14.6 0.0 0.096 12.5 0.0 2.1 2 0 0 2 2 1 0 Torsin AAA_30 PF13604.1 EDO08455.1 - 0.044 13.3 0.0 3.4 7.1 0.0 3.3 2 1 0 2 2 2 0 AAA domain Hydrolase PF00702.21 EDO08455.1 - 0.048 14.0 0.2 0.53 10.6 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3753 PF12575.3 EDO08455.1 - 0.68 9.7 4.8 7.8 6.3 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) PPR PF01535.15 EDO08456.1 - 7.5e-16 56.9 20.2 0.0025 17.6 0.0 8.6 9 1 0 9 9 9 5 PPR repeat PPR_3 PF13812.1 EDO08456.1 - 3.3e-11 42.5 6.0 0.011 15.9 0.0 6.6 8 0 0 8 8 7 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EDO08456.1 - 2.5e-10 40.1 23.5 0.051 13.5 0.1 8.0 4 2 5 9 9 9 5 PPR repeat family TPR_14 PF13428.1 EDO08456.1 - 5.3e-08 32.8 0.5 2.3 9.1 0.1 6.4 5 2 2 7 7 6 1 Tetratricopeptide repeat Clathrin PF00637.15 EDO08456.1 - 5.6e-05 22.7 15.8 0.0022 17.6 4.1 3.5 1 1 2 3 3 3 2 Region in Clathrin and VPS TPR_7 PF13176.1 EDO08456.1 - 0.00019 20.9 10.1 1.2 9.1 0.0 6.3 7 2 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 EDO08456.1 - 0.00022 20.4 5.8 0.0012 17.9 2.8 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EDO08456.1 - 0.00025 21.0 14.7 0.0031 17.5 1.5 4.6 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 RPM2 PF08579.6 EDO08456.1 - 0.00026 21.0 8.5 0.0032 17.5 1.0 3.4 1 1 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) BTAD PF03704.12 EDO08456.1 - 0.00032 21.0 0.8 0.089 13.0 0.0 4.0 3 2 0 3 3 3 1 Bacterial transcriptional activator domain Rad33 PF08730.5 EDO08456.1 - 0.0018 17.7 4.6 0.0022 17.5 2.1 2.0 1 1 0 1 1 1 1 Rad33 TPR_19 PF14559.1 EDO08456.1 - 0.0053 17.0 10.8 3.5 8.0 0.4 5.0 3 1 4 7 7 7 2 Tetratricopeptide repeat DUF2450 PF10475.4 EDO08456.1 - 0.011 14.6 9.8 1.2 8.0 5.1 2.7 1 1 1 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) TPR_16 PF13432.1 EDO08456.1 - 0.013 16.2 1.3 15 6.4 0.1 4.7 4 2 1 5 5 5 0 Tetratricopeptide repeat PPR_1 PF12854.2 EDO08456.1 - 0.028 13.8 2.1 13 5.3 0.0 4.0 5 0 0 5 5 5 0 PPR repeat TPR_2 PF07719.12 EDO08456.1 - 0.029 14.2 16.1 6.9 6.8 0.1 6.6 6 1 1 7 7 7 0 Tetratricopeptide repeat MA3 PF02847.12 EDO08456.1 - 0.16 11.7 2.0 0.32 10.6 0.2 2.3 1 1 2 3 3 3 0 MA3 domain DUF357 PF04010.8 EDO08456.1 - 0.2 11.3 3.7 0.82 9.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF357) TPR_12 PF13424.1 EDO08456.1 - 0.24 11.3 12.6 8.8 6.3 0.9 5.7 3 2 1 4 4 4 0 Tetratricopeptide repeat DUF59 PF01883.14 EDO08457.1 - 1.1e-07 31.6 0.0 2.2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 DS PF01916.12 EDO08457.1 - 0.12 11.4 0.3 0.14 11.2 0.2 1.1 1 0 0 1 1 1 0 Deoxyhypusine synthase TPT PF03151.11 EDO08458.1 - 4.6e-10 39.3 22.2 7e-10 38.7 10.1 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EDO08458.1 - 0.082 11.9 16.0 0.18 10.8 11.1 1.5 1 1 0 1 1 1 0 Nucleotide-sugar transporter EamA PF00892.15 EDO08458.1 - 0.29 11.1 24.5 0.33 10.9 2.7 3.3 3 1 0 3 3 3 0 EamA-like transporter family Ubie_methyltran PF01209.13 EDO08459.1 - 3.8e-73 245.4 0.1 7.9e-73 244.4 0.1 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EDO08459.1 - 1.5e-15 57.4 0.0 4.1e-15 56.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO08459.1 - 2.5e-13 49.8 0.0 7.4e-13 48.3 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO08459.1 - 7.9e-11 42.2 0.0 2.4e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO08459.1 - 8.1e-10 39.0 0.0 2.2e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO08459.1 - 9.4e-10 39.0 0.0 5.5e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO08459.1 - 1.9e-08 34.1 0.0 2.9e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EDO08459.1 - 9.9e-05 22.0 0.0 0.00048 19.8 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 EDO08459.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EDO08459.1 - 0.018 14.2 0.0 0.72 8.9 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase Spo0A_C PF08769.6 EDO08459.1 - 0.071 12.9 0.3 0.26 11.1 0.1 1.9 2 1 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal Peptidase_C78 PF07910.8 EDO08460.1 - 4.5e-45 153.4 0.5 6.6e-45 152.9 0.3 1.2 1 0 0 1 1 1 1 Peptidase family C78 UPF0020 PF01170.13 EDO08461.1 - 1.4e-09 37.8 0.0 5.2e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EDO08461.1 - 0.00038 20.4 0.0 0.0006 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF4205 PF13898.1 EDO08462.1 - 8.5e-56 189.1 0.0 2.8e-55 187.4 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4205) NLE PF08154.7 EDO08463.1 - 1e-15 57.4 0.1 1.9e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.27 EDO08463.1 - 3.1e-12 45.8 0.1 0.00042 20.0 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 EDO08463.1 - 0.0054 16.5 0.0 0.16 11.7 0.0 2.7 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region SET PF00856.23 EDO08464.1 - 2.5e-27 96.1 0.3 9.8e-27 94.2 0.2 2.1 1 0 0 1 1 1 1 SET domain DUF2635 PF10948.3 EDO08464.1 - 0.065 12.5 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) DNA_pol_B_exo1 PF03104.14 EDO08465.1 - 3e-45 154.5 0.1 3e-45 154.5 0.0 2.1 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EDO08465.1 - 1.4e-16 60.3 1.9 9.9e-15 54.2 1.6 2.8 2 1 0 2 2 2 1 DNA polymerase family B DUF1744 PF08490.7 EDO08465.1 - 1.4e-14 53.5 0.0 3.3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo2 PF10108.4 EDO08465.1 - 9.8e-07 28.5 0.6 1.5e-05 24.6 0.4 2.3 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB PGK PF00162.14 EDO08465.1 - 0.00028 19.5 0.0 0.00049 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglycerate kinase RNase_H_2 PF13482.1 EDO08465.1 - 0.00082 19.2 0.0 0.0033 17.2 0.0 2.0 2 0 0 2 2 2 1 RNase_H superfamily CPW_WPC PF09717.5 EDO08467.1 - 8.9e-34 115.9 7.9 3e-19 69.3 2.5 2.4 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) SPATIAL PF15256.1 EDO08467.1 - 0.11 12.5 0.2 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 SPATIAL OmpH PF03938.9 EDO08467.1 - 0.17 11.7 1.2 0.24 11.3 0.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin PF00804.20 EDO08467.1 - 0.17 12.0 1.3 0.27 11.3 0.9 1.3 1 0 0 1 1 1 0 Syntaxin DUF740 PF05340.7 EDO08467.1 - 1.8 6.7 5.7 2.4 6.4 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Pkinase PF00069.20 EDO08469.1 - 4.5e-72 242.3 0.0 5.2e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO08469.1 - 1.7e-36 125.6 0.0 1.9e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO08469.1 - 1.1e-11 44.2 0.0 4.4e-11 42.2 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EDO08469.1 - 0.00029 19.9 0.3 0.00055 19.0 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO08469.1 - 0.00045 20.0 0.0 0.15 11.7 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF2805 PF10985.3 EDO08469.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2805) RIO1 PF01163.17 EDO08469.1 - 0.013 14.8 0.3 0.024 14.0 0.2 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EDO08469.1 - 0.032 13.8 0.2 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DEAD PF00270.24 EDO08470.1 - 9.3e-44 148.8 0.0 1.8e-43 147.9 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EDO08470.1 - 3.6e-21 74.4 0.4 7.4e-21 73.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EDO08470.1 - 1.9e-19 69.3 0.0 3.6e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO08470.1 - 0.0057 16.4 0.0 0.017 14.9 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDO08470.1 - 0.087 12.9 0.3 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain zf-RanBP PF00641.13 EDO08471.1 - 1.7e-07 30.1 0.9 1.7e-07 30.1 0.6 2.0 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RRM_6 PF14259.1 EDO08471.1 - 0.0045 16.9 0.0 0.045 13.7 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Tfb4 PF03850.9 EDO08472.1 - 3.5e-16 59.2 0.8 4.7e-16 58.8 0.6 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 BLOC1_2 PF10046.4 EDO08472.1 - 0.00036 20.6 1.3 0.00063 19.8 0.9 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 VWA_2 PF13519.1 EDO08472.1 - 0.081 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain ER_lumen_recept PF00810.13 EDO08473.1 - 5.3e-52 176.2 15.2 5.3e-52 176.2 10.5 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor Romo1 PF10247.4 EDO08475.1 - 6.2e-22 77.5 12.8 8.1e-22 77.2 8.9 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Proteasome PF00227.21 EDO08476.1 - 9.6e-54 181.5 0.0 1.2e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO08476.1 - 2.4e-13 49.1 0.6 4.1e-13 48.3 0.4 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Proteasome PF00227.21 EDO08477.1 - 1.7e-56 190.5 0.5 2.3e-56 190.1 0.4 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO08477.1 - 3.3e-13 48.6 0.0 6.1e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature FtsJ PF01728.14 EDO08478.1 - 3.4e-54 183.5 0.1 9.3e-54 182.1 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Spb1_C PF07780.7 EDO08478.1 - 4.5e-53 179.9 25.4 4.5e-53 179.9 17.6 3.4 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EDO08478.1 - 1.6e-30 105.7 3.5 1.6e-30 105.7 2.5 4.4 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) ATP-synt_C PF00137.16 EDO08479.1 - 2.8e-30 104.0 26.0 2.9e-17 62.3 5.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Vip3A_N PF12495.3 EDO08480.1 - 0.04 13.6 0.7 0.04 13.6 0.5 1.9 2 0 0 2 2 2 0 Vegetative insecticide protein 3A N terminal DUF2150 PF09920.4 EDO08480.1 - 0.052 13.1 0.5 0.097 12.2 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) Glyco_hydro_56 PF01630.13 EDO08480.1 - 0.091 11.3 0.1 0.16 10.5 0.1 1.3 1 0 0 1 1 1 0 Hyaluronidase TACC PF05010.9 EDO08480.1 - 0.17 11.6 2.4 0.33 10.6 0.7 1.9 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Prefoldin_3 PF13758.1 EDO08480.1 - 0.43 10.3 3.5 0.25 11.1 0.4 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF544 PF04424.8 EDO08481.1 - 0.028 14.2 0.1 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF544) FoP_duplication PF13865.1 EDO08482.1 - 0.0095 16.3 1.1 0.0095 16.3 0.8 1.7 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 S10_plectin PF03501.10 EDO08483.1 - 3.5e-40 135.7 0.1 4.3e-40 135.4 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Methyltransf_10 PF05971.7 EDO08484.1 - 1e-59 202.1 3.1 5.9e-45 153.6 0.1 4.3 3 1 0 3 3 3 3 Protein of unknown function (DUF890) MTS PF05175.9 EDO08484.1 - 6.8e-08 32.0 0.0 1.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EDO08484.1 - 3.2e-06 26.5 0.0 5.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EDO08484.1 - 7.8e-06 25.9 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO08484.1 - 0.051 14.1 0.0 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 EDO08484.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RRM_1 PF00076.17 EDO08485.1 - 2.2e-21 75.2 2.9 1.7e-19 69.1 0.2 3.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO08485.1 - 2.7e-20 72.1 1.4 2.2e-15 56.3 0.0 3.3 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO08485.1 - 1.9e-06 27.6 0.4 0.00012 21.9 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1664 PF07889.7 EDO08486.1 - 4e-05 23.3 33.5 0.011 15.4 2.5 3.9 2 1 2 4 4 4 3 Protein of unknown function (DUF1664) ERM PF00769.14 EDO08486.1 - 0.00012 21.7 18.1 0.00012 21.7 12.5 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 EDO08486.1 - 0.00047 19.4 3.2 0.00047 19.4 2.2 2.2 1 1 2 3 3 3 1 Reovirus sigma C capsid protein DUF869 PF05911.6 EDO08486.1 - 0.0012 17.1 39.1 0.0019 16.5 27.1 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DUF4164 PF13747.1 EDO08486.1 - 0.0027 17.7 7.9 0.0027 17.7 5.5 3.7 1 1 1 3 3 3 1 Domain of unknown function (DUF4164) IncA PF04156.9 EDO08486.1 - 0.0037 16.8 13.8 0.0037 16.8 9.5 2.7 1 1 1 2 2 2 1 IncA protein DUF3019 PF11456.3 EDO08486.1 - 0.019 15.2 3.0 0.019 15.2 2.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3019) Cast PF10174.4 EDO08486.1 - 0.025 12.6 35.6 0.11 10.5 13.1 2.1 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone Helicase_Sgs1 PF11408.3 EDO08486.1 - 0.13 12.0 4.1 7.6 6.4 1.0 3.3 2 1 0 2 2 2 0 Sgs1 RecQ helicase WEMBL PF05701.6 EDO08486.1 - 0.28 9.5 39.3 1.8 6.9 27.2 1.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light AAA_13 PF13166.1 EDO08486.1 - 0.71 8.2 46.0 0.011 14.3 25.3 2.1 1 1 1 2 2 2 0 AAA domain Syntaxin-6_N PF09177.6 EDO08486.1 - 0.78 10.1 25.4 1.9 8.9 5.6 3.9 2 1 2 4 4 3 0 Syntaxin 6, N-terminal MCPsignal PF00015.16 EDO08486.1 - 2.3 7.7 26.4 0.58 9.6 8.0 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.7 EDO08486.1 - 4.1 7.1 28.2 0.2 11.4 5.8 3.7 1 1 4 5 5 5 0 Laminin Domain II APG6 PF04111.7 EDO08486.1 - 4.2 6.3 42.8 0.023 13.7 14.6 3.2 1 1 3 4 4 4 0 Autophagy protein Apg6 GAS PF13851.1 EDO08486.1 - 4.3 6.4 47.0 0.023 13.9 11.1 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EDO08486.1 - 4.3 7.1 46.9 0.035 13.9 12.7 3.7 1 1 3 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF745 PF05335.8 EDO08486.1 - 4.5 6.7 26.0 1.7 8.0 3.9 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF745) DUF2968 PF11180.3 EDO08486.1 - 8.3 5.7 21.9 0.038 13.3 2.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) DUF3735 PF12537.3 EDO08486.1 - 9.3 6.3 7.6 4 7.5 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3735) DUF3399 PF11879.3 EDO08487.1 - 0.033 14.3 3.5 0.067 13.4 2.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3399) Oligomerisation PF02410.10 EDO08490.1 - 6.5e-07 29.3 0.1 1.2e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 Oligomerisation domain Ribosomal_S7e PF01251.13 EDO08491.1 - 2.6e-62 209.6 5.8 3.1e-62 209.4 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e NadA PF02445.11 EDO08491.1 - 0.054 12.3 0.2 0.063 12.0 0.1 1.1 1 0 0 1 1 1 0 Quinolinate synthetase A protein FCH PF00611.18 EDO08492.1 - 2.9e-05 24.1 0.0 0.00018 21.6 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DnaJ PF00226.26 EDO08493.1 - 7.3e-05 22.4 0.0 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L21p PF00829.16 EDO08494.1 - 4.7e-09 36.2 0.0 1e-07 32.0 0.0 2.4 1 1 0 1 1 1 1 Ribosomal prokaryotic L21 protein RIO1 PF01163.17 EDO08495.1 - 3.7e-44 150.3 0.1 6e-44 149.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EDO08495.1 - 2.2e-29 101.3 0.1 1.6e-28 98.5 0.0 2.2 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 EDO08495.1 - 3e-08 33.6 1.8 0.00025 20.8 0.5 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EDO08495.1 - 1.2e-05 24.4 0.0 0.0066 15.5 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_45 PF14947.1 EDO08495.1 - 0.082 12.7 0.9 2.5 7.9 0.0 3.2 4 0 0 4 4 4 0 Winged helix-turn-helix DUF3456 PF11938.3 EDO08496.1 - 0.016 15.2 0.1 0.032 14.2 0.1 1.5 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP PNRC PF15365.1 EDO08496.1 - 0.86 9.6 5.5 0.91 9.5 2.2 2.4 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator UPF0160 PF03690.8 EDO08497.1 - 3.4e-109 365.1 0.1 3.8e-109 364.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Rad1 PF02144.11 EDO08498.1 - 6.8e-06 25.0 0.2 0.0037 16.0 0.0 2.1 1 1 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Peptidase_M22 PF00814.20 EDO08499.1 - 1.9e-45 155.4 0.0 4.4e-45 154.2 0.0 1.5 1 1 0 1 1 1 1 Glycoprotease family Ribosomal_S10 PF00338.17 EDO08500.1 - 1.8e-27 95.0 0.0 3.7e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ABC_tran PF00005.22 EDO08501.1 - 6e-35 120.5 0.0 1.3e-18 67.6 0.0 2.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDO08501.1 - 3e-13 50.3 7.2 0.00073 19.5 0.8 4.2 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EDO08501.1 - 4.1e-12 45.7 0.1 0.00091 18.5 0.0 3.2 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RLI PF04068.10 EDO08501.1 - 2.6e-11 42.9 6.5 6.1e-11 41.7 4.5 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.22 EDO08501.1 - 4.7e-08 32.2 2.9 4.7e-08 32.2 2.0 2.4 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_15 PF13175.1 EDO08501.1 - 4.2e-07 29.3 0.6 0.12 11.3 0.1 3.4 3 0 0 3 3 3 3 AAA ATPase domain DUF258 PF03193.11 EDO08501.1 - 3.9e-06 26.1 1.8 0.13 11.3 0.0 3.6 4 0 0 4 4 4 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDO08501.1 - 4.2e-06 26.9 0.0 0.0015 18.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EDO08501.1 - 1.5e-05 24.4 0.4 0.057 12.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.2 EDO08501.1 - 4.2e-05 23.2 2.4 4.2e-05 23.2 1.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.10 EDO08501.1 - 9e-05 21.3 0.0 0.16 10.6 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein NACHT PF05729.7 EDO08501.1 - 0.00025 20.7 1.8 0.022 14.3 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AAA PF00004.24 EDO08501.1 - 0.00031 20.9 0.0 0.33 11.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EDO08501.1 - 0.00044 20.6 0.1 0.069 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.2 EDO08501.1 - 0.00059 20.1 1.5 0.00059 20.1 1.1 2.6 2 1 2 4 4 3 2 4Fe-4S dicluster domain MobB PF03205.9 EDO08501.1 - 0.00059 19.5 0.8 0.16 11.7 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_21 PF14697.1 EDO08501.1 - 0.00063 19.5 12.6 0.0013 18.5 8.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EDO08501.1 - 0.00071 19.3 2.4 0.00071 19.3 1.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.1 EDO08501.1 - 0.00092 19.2 0.1 0.27 11.2 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EDO08501.1 - 0.0014 18.3 0.2 1.4 8.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) VirE PF05272.6 EDO08501.1 - 0.0015 18.0 0.0 2.3 7.6 0.0 3.0 3 0 0 3 3 3 1 Virulence-associated protein E RNA_helicase PF00910.17 EDO08501.1 - 0.0023 18.0 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EDO08501.1 - 0.0026 17.6 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDO08501.1 - 0.0029 17.9 0.5 0.26 11.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain Fer4_10 PF13237.1 EDO08501.1 - 0.0046 16.7 1.4 0.0046 16.7 1.0 2.0 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_17 PF13207.1 EDO08501.1 - 0.0053 17.5 2.7 1.3 9.8 0.2 3.1 2 2 0 2 2 2 1 AAA domain SRP54 PF00448.17 EDO08501.1 - 0.008 15.6 4.1 0.12 11.7 0.1 2.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EDO08501.1 - 0.0086 15.5 0.1 1.7 7.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EDO08501.1 - 0.015 14.8 0.4 0.17 11.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Fer4_3 PF12798.2 EDO08501.1 - 0.016 15.7 4.3 0.016 15.7 3.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_16 PF13484.1 EDO08501.1 - 0.018 15.7 0.4 0.018 15.7 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 EDO08501.1 - 0.022 15.0 14.6 0.028 14.6 8.8 2.2 2 1 0 2 2 1 0 4Fe-4S dicluster domain Miro PF08477.8 EDO08501.1 - 0.023 15.2 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 EDO08501.1 - 0.031 13.8 0.8 0.77 9.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain Septin PF00735.13 EDO08501.1 - 0.045 12.7 0.0 1.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Septin Thymidylate_kin PF02223.12 EDO08501.1 - 0.046 13.0 1.3 11 5.3 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase AAA_14 PF13173.1 EDO08501.1 - 0.048 13.5 0.3 7.8 6.4 0.0 3.0 2 1 1 3 3 3 0 AAA domain Mg_chelatase PF01078.16 EDO08501.1 - 0.064 12.3 1.4 0.14 11.3 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Fer4_8 PF13183.1 EDO08501.1 - 0.066 13.2 8.4 0.2 11.7 6.0 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain SbcCD_C PF13558.1 EDO08501.1 - 0.072 13.0 0.0 27 4.7 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EDO08501.1 - 0.084 12.2 0.1 6.2 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 EDO08501.1 - 0.1 12.1 0.3 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EDO08501.1 - 0.13 12.2 0.1 11 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EDO08501.1 - 0.16 10.7 0.0 3.2 6.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 EDO08501.1 - 0.54 9.9 3.8 6.7 6.3 0.0 2.8 3 0 0 3 3 2 0 NTPase Fer4_4 PF12800.2 EDO08501.1 - 6 7.4 16.0 0.055 13.8 1.6 2.6 2 0 0 2 2 1 0 4Fe-4S binding domain DUF947 PF06102.7 EDO08502.1 - 1e-28 100.2 14.4 1e-28 100.2 10.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF947) DUF3427 PF11907.3 EDO08502.1 - 0.0094 14.9 1.9 0.015 14.2 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3427) Rpp20 PF12328.3 EDO08502.1 - 0.014 15.0 2.7 0.014 15.0 1.9 2.4 3 0 0 3 3 3 0 Rpp20 subunit of nuclear RNase MRP and P RAP PF08373.5 EDO08504.1 - 5.8e-24 83.6 0.2 5.8e-24 83.6 0.1 1.6 2 0 0 2 2 2 1 RAP domain MMtag PF10159.4 EDO08504.1 - 0.0093 15.9 1.0 0.0093 15.9 0.7 2.4 2 1 0 2 2 2 1 Kinase phosphorylation protein Glyco_tranf_2_4 PF13704.1 EDO08504.1 - 0.013 15.8 0.1 0.03 14.6 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF2407_C PF13373.1 EDO08504.1 - 4.9 7.0 5.5 0.63 9.9 0.7 1.7 2 0 0 2 2 2 0 DUF2407 C-terminal domain Chloroplast_duf PF14476.1 EDO08505.1 - 0.0027 16.5 0.4 0.0031 16.3 0.3 1.2 1 0 0 1 1 1 1 Petal formation-expressed Reo_sigmaC PF04582.7 EDO08505.1 - 0.003 16.7 0.7 0.42 9.7 0.0 2.0 2 0 0 2 2 2 2 Reovirus sigma C capsid protein BBP1_C PF15272.1 EDO08505.1 - 0.0057 16.2 0.3 0.0057 16.2 0.2 2.3 2 1 0 2 2 2 1 Spindle pole body component BBP1, C-terminal MscS_porin PF12795.2 EDO08505.1 - 0.0081 15.5 7.9 0.17 11.1 1.6 2.1 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain Trans_reg_C PF00486.23 EDO08505.1 - 0.01 15.7 0.2 0.022 14.6 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal CorA PF01544.13 EDO08505.1 - 0.01 14.9 1.7 0.011 14.7 1.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IFT57 PF10498.4 EDO08505.1 - 0.049 12.3 8.9 0.14 10.8 0.6 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF1611 PF07755.6 EDO08505.1 - 0.05 12.2 0.3 0.062 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1611) AAA_23 PF13476.1 EDO08505.1 - 0.13 12.5 3.5 0.2 11.9 2.4 1.2 1 0 0 1 1 1 0 AAA domain FlaC_arch PF05377.6 EDO08505.1 - 0.17 11.8 8.4 3.3 7.6 0.5 3.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.6 EDO08505.1 - 0.22 11.9 6.8 0.66 10.4 1.7 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 EDO08505.1 - 0.4 10.4 3.9 0.74 9.6 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YgaB PF14182.1 EDO08505.1 - 0.43 10.8 9.9 4.1 7.6 2.7 2.5 2 1 0 2 2 2 0 YgaB-like protein SpoIIIAH PF12685.2 EDO08505.1 - 0.53 9.7 8.0 0.84 9.0 5.5 1.3 1 1 0 1 1 1 0 SpoIIIAH-like protein SRI PF08236.6 EDO08505.1 - 0.55 10.2 4.8 0.29 11.1 1.3 2.0 1 1 1 2 2 2 0 SRI (Set2 Rpb1 interacting) domain BLOC1_2 PF10046.4 EDO08505.1 - 0.69 10.0 6.6 3.4 7.8 1.1 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 EDO08505.1 - 0.7 10.0 7.8 1.6 8.8 0.7 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 EDO08505.1 - 0.85 8.5 14.1 0.58 9.0 1.6 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF883 PF05957.8 EDO08505.1 - 1.2 9.5 4.3 5.3 7.5 0.2 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF607 PF04678.8 EDO08505.1 - 1.3 8.9 5.2 2.6 7.9 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF607 DUF972 PF06156.8 EDO08505.1 - 1.5 9.1 7.1 0.89 9.9 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Syntaxin PF00804.20 EDO08505.1 - 2.6 8.2 9.9 57 3.9 6.7 2.5 1 1 0 1 1 1 0 Syntaxin DUF2203 PF09969.4 EDO08505.1 - 2.8 8.1 6.1 15 5.8 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Mnd1 PF03962.10 EDO08505.1 - 3.8 7.1 10.5 13 5.3 7.3 1.8 1 1 0 1 1 1 0 Mnd1 family Wbp11 PF09429.5 EDO08505.1 - 7 6.7 11.4 1 9.3 3.9 2.3 2 1 0 2 2 2 0 WW domain binding protein 11 FANCI_S1 PF14675.1 EDO08506.1 - 0.032 13.5 0.7 0.07 12.4 0.5 1.5 1 0 0 1 1 1 0 FANCI solenoid 1 NAC PF01849.13 EDO08507.1 - 1.8e-22 78.5 0.2 3.1e-22 77.8 0.2 1.4 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 EDO08507.1 - 0.0049 16.6 0.2 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain HAND PF09110.6 EDO08508.1 - 0.023 15.0 6.0 1.7 9.0 0.1 2.3 2 0 0 2 2 2 0 HAND DUF4239 PF14023.1 EDO08508.1 - 0.027 13.8 0.4 0.027 13.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Ax_dynein_light PF10211.4 EDO08508.1 - 1.6 8.5 14.0 0.064 13.0 5.0 1.9 2 1 0 2 2 2 0 Axonemal dynein light chain Methyltrans_RNA PF04452.9 EDO08509.1 - 3.6e-39 134.1 0.0 4.2e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase DUF2893 PF11459.3 EDO08509.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknwon function (DUF2893) FAST_1 PF06743.10 EDO08510.1 - 1.9e-09 37.0 7.7 0.046 13.4 0.1 7.5 6 1 2 8 8 8 4 FAST kinase-like protein, subdomain 1 Med12 PF09497.5 EDO08511.1 - 0.033 14.1 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Transcription mediator complex subunit Med12 HEAT_2 PF13646.1 EDO08512.1 - 3.3e-05 24.0 1.1 3.6 7.9 0.0 5.2 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EDO08512.1 - 0.00026 21.3 2.3 0.13 12.7 0.0 5.0 4 0 0 4 4 4 1 HEAT-like repeat HEAT_PBS PF03130.11 EDO08512.1 - 0.053 14.0 0.9 14 6.5 0.0 3.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat HEAT PF02985.17 EDO08512.1 - 0.069 13.2 10.1 1.1 9.5 0.0 5.6 6 0 0 6 6 6 0 HEAT repeat B3_4 PF03483.12 EDO08515.1 - 2e-17 63.1 0.0 3.1e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EDO08515.1 - 1.6e-14 53.4 0.0 6.7e-12 45.0 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain AP2 PF00847.15 EDO08516.1 - 1.6e-07 31.3 0.6 3e-07 30.4 0.4 1.4 1 0 0 1 1 1 1 AP2 domain PPTA PF01239.17 EDO08517.1 - 1.6e-17 61.9 9.9 1.2e-05 24.4 0.1 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Sec7 PF01369.15 EDO08518.1 - 1.3e-74 250.0 0.6 3.2e-74 248.7 0.4 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EDO08518.1 - 7.9e-14 51.4 4.6 7.9e-14 51.4 3.2 3.8 2 1 1 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal EF_TS PF00889.14 EDO08519.1 - 5.3e-08 32.4 0.1 8.2e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor TS UBA_4 PF14555.1 EDO08519.1 - 0.00043 19.7 0.0 0.00083 18.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 EDO08519.1 - 0.029 14.1 0.1 0.094 12.5 0.0 1.9 1 1 0 1 1 1 0 UBA/TS-N domain PMI_typeI PF01238.16 EDO08520.1 - 6.5e-48 163.5 0.0 3.7e-46 157.7 0.0 2.3 1 1 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 EDO08520.1 - 0.065 12.9 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 AraC-like ligand binding domain Pkinase PF00069.20 EDO08521.1 - 7.1e-38 130.2 0.0 1.5e-36 125.8 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO08521.1 - 1.7e-10 40.4 0.0 3.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EDO08521.1 - 0.14 11.4 0.0 13 5.0 0.0 2.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Gpi1 PF05024.10 EDO08522.1 - 6.5e-28 97.6 9.3 6.5e-28 97.6 6.4 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Sm_multidrug_ex PF06695.6 EDO08522.1 - 0.46 10.6 7.9 3.1 7.9 1.6 2.5 1 1 1 2 2 2 0 Putative small multi-drug export protein Amidohydro_2 PF04909.9 EDO08523.1 - 2.1e-07 30.7 0.0 2.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase ELFV_dehydrog PF00208.16 EDO08524.1 - 5.8e-43 147.2 0.0 1.2e-42 146.1 0.0 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EDO08524.1 - 1.5e-20 72.3 0.0 5.6e-15 53.9 0.0 2.3 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EDO08524.1 - 0.00033 20.2 0.0 0.0019 17.7 0.0 2.4 1 1 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF976 PF06162.7 EDO08524.1 - 0.032 13.7 0.0 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF976) Gryzun PF07919.7 EDO08525.1 - 3.1e-07 29.1 0.5 5.8e-07 28.2 0.0 1.7 2 0 0 2 2 2 1 Gryzun, putative trafficking through Golgi Transglut_C PF00927.17 EDO08525.1 - 0.06 13.3 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain FeoB_C PF07664.7 EDO08526.1 - 0.16 11.4 0.1 0.16 11.4 0.1 3.7 5 0 0 5 5 5 0 Ferrous iron transport protein B C terminus DUF202 PF02656.10 EDO08526.1 - 0.58 10.4 0.0 0.58 10.4 0.0 3.9 3 2 0 3 3 3 0 Domain of unknown function (DUF202) TRIQK PF15168.1 EDO08526.1 - 2.5 8.0 5.1 8.1 6.4 1.4 2.9 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family DUF912 PF06024.7 EDO08526.1 - 4.5 7.3 5.5 2.2 8.3 0.0 2.8 2 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SNF2_N PF00176.18 EDO08527.1 - 5.3e-30 104.2 0.0 9.7e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO08527.1 - 1.4e-09 37.6 0.0 3.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO08527.1 - 0.0011 18.8 0.0 0.016 15.0 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit S1 PF00575.18 EDO08528.1 - 1.1e-11 44.5 0.2 9.2e-05 22.4 0.0 2.7 2 0 0 2 2 2 2 S1 RNA binding domain DUF3070 PF11270.3 EDO08528.1 - 0.053 13.3 1.7 0.25 11.1 1.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3070) Fasciclin PF02469.17 EDO08529.1 - 5.1e-11 42.6 0.0 6.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain Ribosomal_L7Ae PF01248.21 EDO08530.1 - 3.5e-26 90.5 0.2 4.6e-26 90.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EDO08530.1 - 0.022 14.6 0.1 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 S-AdoMet_synt_C PF02773.11 EDO08531.1 - 1.9e-58 196.1 0.0 3e-58 195.4 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EDO08531.1 - 3e-46 156.2 0.0 5.8e-46 155.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EDO08531.1 - 5.3e-42 142.1 0.2 9.1e-42 141.3 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Amidase PF01425.16 EDO08532.1 - 1.4e-83 281.2 0.0 1.9e-83 280.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Antigen_Bd37 PF11641.3 EDO08532.1 - 0.025 13.8 0.2 0.044 13.0 0.2 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein zf-C3HC4_2 PF13923.1 EDO08533.1 - 2.4e-12 46.6 10.0 3.4e-12 46.1 6.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO08533.1 - 1.5e-10 40.6 7.7 2.1e-10 40.1 5.3 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDO08533.1 - 2.6e-10 39.7 8.1 3.8e-10 39.2 5.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO08533.1 - 1.9e-09 37.1 11.3 2.6e-09 36.7 7.8 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDO08533.1 - 4.3e-09 35.9 5.8 6.5e-09 35.3 4.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO08533.1 - 1.4e-08 34.3 1.3 1.2e-07 31.3 0.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EDO08533.1 - 1.3e-06 28.1 8.9 2e-06 27.5 6.2 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EDO08533.1 - 7e-05 22.8 6.2 0.00011 22.1 4.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger Rtf2 PF04641.7 EDO08533.1 - 0.00032 19.9 0.1 0.00043 19.5 0.1 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EDO08533.1 - 0.0068 15.9 3.9 0.011 15.2 2.7 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EDO08533.1 - 0.011 15.4 3.3 0.017 14.9 2.3 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.10 EDO08533.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 U-box domain zf-Apc11 PF12861.2 EDO08533.1 - 0.065 13.0 6.7 0.1 12.4 4.7 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EDO08533.1 - 0.17 11.4 7.5 0.61 9.7 5.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RRN7 PF11781.3 EDO08533.1 - 0.2 11.2 0.0 0.2 11.2 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Baculo_IE-1 PF05290.6 EDO08533.1 - 0.21 11.3 4.0 0.31 10.7 2.8 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-MIZ PF02891.15 EDO08533.1 - 1.5 8.3 9.0 2.4 7.7 6.2 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger IBR PF01485.16 EDO08533.1 - 2.4 8.0 10.2 4.8 7.1 5.6 2.3 1 1 1 2 2 2 0 IBR domain EF-hand_7 PF13499.1 EDO08534.1 - 6.8e-05 22.9 0.1 0.00015 21.8 0.0 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EDO08534.1 - 0.00011 21.7 0.1 0.00081 19.0 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EDO08534.1 - 0.0049 16.0 0.5 0.014 14.6 0.1 2.0 2 0 0 2 2 2 1 EF hand PSCyt2 PF07583.6 EDO08534.1 - 0.0074 15.8 0.0 0.16 11.4 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1549) EF-hand_5 PF13202.1 EDO08534.1 - 0.024 13.9 0.1 0.069 12.5 0.1 1.8 1 0 0 1 1 1 0 EF hand SapB_1 PF05184.10 EDO08534.1 - 0.09 12.6 0.1 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Saposin-like type B, region 1 Glycos_trans_3N PF02885.12 EDO08534.1 - 0.1 12.2 0.0 0.8 9.3 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain EF-hand_9 PF14658.1 EDO08534.1 - 0.13 12.2 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain Patatin PF01734.17 EDO08536.1 - 0.00071 19.5 0.2 0.0023 17.8 0.1 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase AAA PF00004.24 EDO08537.1 - 9.8e-09 35.5 0.0 2.6e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDO08537.1 - 6e-05 23.1 0.1 0.05 13.5 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EDO08537.1 - 0.002 18.2 0.0 0.016 15.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EDO08537.1 - 0.0029 17.0 0.1 0.0078 15.6 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.7 EDO08537.1 - 0.0064 15.5 0.0 0.048 12.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EDO08537.1 - 0.034 12.8 0.0 0.052 12.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus ResIII PF04851.10 EDO08537.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit LSM PF01423.17 EDO08540.1 - 0.00021 20.7 0.0 0.00044 19.7 0.0 1.5 1 0 0 1 1 1 1 LSM domain WD40 PF00400.27 EDO08541.1 - 1.1e-05 25.1 0.1 0.26 11.2 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat UQ_con PF00179.21 EDO08542.1 - 2.6e-45 153.2 0.1 3e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO08542.1 - 0.038 13.7 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RRM_1 PF00076.17 EDO08543.1 - 2.3e-06 27.1 0.0 0.017 14.7 0.0 3.1 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO08543.1 - 0.00059 19.7 0.1 2.6 8.0 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NRDE-2 PF08424.5 EDO08543.1 - 0.0013 17.6 0.1 8.2 5.2 0.0 3.2 2 1 1 3 3 3 3 NRDE-2, necessary for RNA interference RRM_5 PF13893.1 EDO08543.1 - 0.018 14.9 0.0 9.5 6.1 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMS19_N PF14500.1 EDO08543.1 - 0.11 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Arm PF00514.18 EDO08544.1 - 3.3e-79 258.2 4.8 1.1e-14 53.6 0.0 8.3 8 0 0 8 8 8 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EDO08544.1 - 7.6e-24 83.8 0.0 2.8e-09 37.1 0.0 5.2 1 1 4 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 EDO08544.1 - 6.1e-23 80.6 0.0 1.8e-09 37.8 0.0 5.1 4 2 0 4 4 4 3 HEAT-like repeat HEAT PF02985.17 EDO08544.1 - 2.2e-16 58.3 0.1 7.5e-05 22.4 0.0 6.2 6 0 0 6 6 6 4 HEAT repeat Arm_2 PF04826.8 EDO08544.1 - 1.5e-09 37.3 0.0 0.0011 18.1 0.0 4.3 1 1 3 4 4 4 3 Armadillo-like IBB PF01749.15 EDO08544.1 - 8.4e-07 29.0 7.1 5.7e-06 26.4 4.9 2.3 1 1 0 1 1 1 1 Importin beta binding domain Adaptin_N PF01602.15 EDO08544.1 - 3.3e-05 22.4 0.0 0.014 13.7 0.0 2.6 1 1 2 3 3 3 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 EDO08544.1 - 8.2e-05 22.5 0.0 1.8 8.5 0.0 3.9 4 1 1 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 EDO08544.1 - 0.00029 19.2 0.0 0.0078 14.5 0.0 2.2 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EDO08544.1 - 0.0049 17.2 0.1 0.52 10.9 0.0 3.8 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat Neurochondrin PF05536.6 EDO08544.1 - 0.017 13.4 0.1 1.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Neurochondrin YadA_stalk PF05662.9 EDO08544.1 - 6.7 6.6 9.5 0.62 9.9 1.1 3.0 3 0 0 3 3 3 0 Coiled stalk of trimeric autotransporter adhesin Nucleoplasmin PF03066.10 EDO08545.1 - 4.1e-08 32.8 0.8 4.7e-08 32.6 0.5 1.1 1 0 0 1 1 1 1 Nucleoplasmin CDC45 PF02724.9 EDO08545.1 - 0.052 11.5 1.4 0.056 11.4 1.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.1 EDO08545.1 - 1.1 9.4 6.4 1.7 8.8 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 EDO08545.1 - 2.4 7.7 6.5 3.3 7.2 4.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 EDO08545.1 - 3.9 7.7 11.6 5.8 7.2 8.0 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 EDO08545.1 - 7.2 6.9 7.9 11 6.4 5.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_S17 PF00366.15 EDO08546.1 - 2.4e-11 43.4 0.7 3.8e-11 42.8 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 DUF2040 PF09745.4 EDO08547.1 - 1.2e-19 70.3 6.7 1.9e-18 66.5 1.7 2.5 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 55 (DUF2040) RNA_pol_Rpb5_C PF01191.14 EDO08548.1 - 4.3e-34 115.9 0.3 7.8e-34 115.1 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EDO08548.1 - 2e-23 82.5 0.7 3.7e-23 81.7 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EDO08548.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Restriction endonuclease RC-P840_PscD PF10657.4 EDO08548.1 - 0.12 12.2 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD Rieske PF00355.21 EDO08549.1 - 2.1e-16 59.2 0.0 4e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 EDO08549.1 - 0.0027 17.9 0.3 0.0063 16.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region FXa_inhibition PF14670.1 EDO08549.1 - 0.28 11.3 2.2 0.47 10.6 1.5 1.3 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site Mem_trans PF03547.13 EDO08550.1 - 0.01 14.1 0.2 0.01 14.1 0.2 2.7 2 1 1 3 3 3 0 Membrane transport protein ODV-E18 PF10717.4 EDO08550.1 - 0.6 9.5 6.1 4.3 6.8 0.3 3.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Coatomer_WDAD PF04053.9 EDO08551.1 - 1.2e-99 334.1 7.7 2.5e-99 333.0 5.4 1.6 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 EDO08551.1 - 5.3e-53 175.1 8.8 5.7e-11 41.8 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat COPI_C PF06957.6 EDO08551.1 - 9e-31 106.8 0.2 1.7e-30 105.9 0.1 1.4 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Nup160 PF11715.3 EDO08551.1 - 0.026 12.6 8.4 0.73 7.9 0.2 3.4 2 2 1 3 3 3 0 Nucleoporin Nup120/160 UQ_con PF00179.21 EDO08552.1 - 3e-40 136.9 0.0 3.2e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDO08552.1 - 0.0024 17.7 0.1 0.0031 17.3 0.1 1.2 1 0 0 1 1 1 1 RWD domain AAA_23 PF13476.1 EDO08553.1 - 4e-22 79.5 8.3 4e-22 79.5 5.8 6.3 1 1 1 2 2 2 1 AAA domain SMC_N PF02463.14 EDO08553.1 - 3.6e-11 42.7 19.7 1.1e-07 31.3 0.0 3.6 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EDO08553.1 - 4.8e-09 36.0 0.0 1.5e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EDO08553.1 - 5e-08 31.8 92.3 0.00093 17.7 1.8 6.0 1 1 3 6 6 6 4 AAA domain AAA_21 PF13304.1 EDO08553.1 - 2.4e-06 27.7 12.7 0.00019 21.5 0.0 4.2 4 2 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EDO08553.1 - 0.00066 19.1 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EDO08553.1 - 0.21 11.5 1.6 0.95 9.4 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EDO08553.1 - 0.21 11.7 0.0 0.21 11.7 0.0 4.3 4 1 1 5 5 5 0 AAA domain Beta-Casp PF10996.3 EDO08555.1 - 1.5e-17 63.7 0.1 4e-17 62.3 0.0 1.7 2 0 0 2 2 2 1 Beta-Casp domain zf-C3HC4_2 PF13923.1 EDO08556.1 - 3.2e-08 33.4 14.0 8.1e-08 32.1 9.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO08556.1 - 6.2e-08 32.1 14.3 1.5e-07 30.9 9.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO08556.1 - 2.2e-07 30.4 13.0 5.7e-07 29.1 9.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO08556.1 - 2.6e-07 30.2 14.3 7.3e-07 28.8 9.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EDO08556.1 - 9.8e-06 25.3 12.8 9.8e-06 25.3 8.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 EDO08556.1 - 0.00021 21.0 11.4 0.00047 19.9 7.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EDO08556.1 - 0.003 17.3 6.2 0.003 17.3 4.3 1.9 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EDO08556.1 - 0.0081 15.8 9.1 0.024 14.3 6.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger DUF972 PF06156.8 EDO08556.1 - 0.011 16.0 18.5 0.42 10.9 0.5 5.3 3 2 1 4 4 4 0 Protein of unknown function (DUF972) zf-RING_4 PF14570.1 EDO08556.1 - 0.017 14.6 9.7 0.043 13.4 6.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Filament PF00038.16 EDO08556.1 - 0.03 13.8 26.5 0.62 9.4 4.0 4.1 3 1 1 4 4 4 0 Intermediate filament protein zf-rbx1 PF12678.2 EDO08556.1 - 0.077 13.1 10.4 0.29 11.2 7.2 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EDO08556.1 - 0.085 12.4 8.4 0.051 13.1 4.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 GBP_C PF02841.9 EDO08556.1 - 0.096 11.8 14.0 0.059 12.5 7.5 2.1 1 1 1 2 2 2 0 Guanylate-binding protein, C-terminal domain HrpB7 PF09486.5 EDO08556.1 - 0.17 11.7 17.9 0.12 12.3 3.8 4.0 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB7) DUF904 PF06005.7 EDO08556.1 - 0.19 12.0 20.5 14 6.0 0.0 5.8 5 1 1 6 6 6 0 Protein of unknown function (DUF904) FliD_N PF02465.13 EDO08556.1 - 0.36 11.2 7.9 1.3 9.3 0.8 3.2 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus bZIP_1 PF00170.16 EDO08556.1 - 0.44 10.5 29.6 0.68 9.9 0.3 6.4 5 2 2 7 7 6 0 bZIP transcription factor bZIP_2 PF07716.10 EDO08556.1 - 0.89 9.4 21.8 6.6 6.6 0.3 5.9 5 0 0 5 5 5 0 Basic region leucine zipper DivIC PF04977.10 EDO08556.1 - 0.91 9.0 17.8 12 5.4 0.2 5.0 5 0 0 5 5 5 0 Septum formation initiator Reo_sigmaC PF04582.7 EDO08556.1 - 1 8.4 13.0 0.5 9.4 1.9 3.1 3 1 1 4 4 4 0 Reovirus sigma C capsid protein DivIVA PF05103.8 EDO08556.1 - 2.2 8.3 17.0 3 7.9 0.2 4.0 2 1 1 3 3 3 0 DivIVA protein TMF_TATA_bd PF12325.3 EDO08556.1 - 2.7 7.7 27.3 3.7 7.3 0.5 4.1 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF641 PF04859.7 EDO08556.1 - 8.9 6.0 15.2 1.9 8.2 1.3 3.7 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) HSP70 PF00012.15 EDO08557.1 - 4.7e-262 870.2 6.6 5.3e-262 870.1 4.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO08557.1 - 4.8e-15 54.9 0.4 7e-14 51.1 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EDO08557.1 - 0.0012 17.7 0.3 0.053 12.3 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EDO08557.1 - 0.014 14.5 1.1 0.096 11.7 0.1 2.7 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EDO08557.1 - 0.039 13.5 0.0 0.35 10.4 0.0 2.5 3 0 0 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 EDO08557.1 - 0.052 12.4 0.1 0.18 10.7 0.0 1.9 2 0 0 2 2 2 0 StbA protein FtsA PF14450.1 EDO08557.1 - 0.22 11.3 5.7 3.1 7.6 0.3 3.9 2 2 0 2 2 2 0 Cell division protein FtsA Radical_SAM PF04055.16 EDO08558.1 - 5.4e-13 49.4 0.1 1.8e-12 47.7 0.1 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EDO08558.1 - 7.3e-07 29.1 0.5 2.9e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family LPP PF04728.8 EDO08558.1 - 0.074 12.8 0.9 21 5.0 0.1 3.4 1 1 3 4 4 4 0 Lipoprotein leucine-zipper Helicase_C_3 PF13625.1 EDO08559.1 - 3.2e-21 75.4 0.1 1.8e-20 73.0 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO08559.1 - 3.9e-15 56.1 0.0 1.3e-14 54.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDO08559.1 - 6.5e-12 45.1 0.1 1.1e-10 41.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO08559.1 - 4.2e-06 26.3 0.0 1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SpoVIF PF14069.1 EDO08559.1 - 0.018 14.7 0.1 0.7 9.6 0.0 2.6 2 0 0 2 2 2 0 Stage VI sporulation protein F AAA_22 PF13401.1 EDO08559.1 - 0.027 14.5 0.1 0.12 12.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain Y_phosphatase3 PF13350.1 EDO08559.1 - 0.16 12.1 1.7 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 Tyrosine phosphatase family Dynamin_M PF01031.15 EDO08560.1 - 7.4e-95 317.1 0.3 1.4e-94 316.2 0.2 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EDO08560.1 - 4.4e-51 173.0 1.3 2.8e-50 170.4 0.0 2.4 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EDO08560.1 - 5.2e-29 99.9 4.8 1.6e-28 98.4 3.3 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EDO08560.1 - 2.4e-05 24.2 0.3 0.00018 21.4 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Condensin2nSMC PF12422.3 EDO08560.1 - 0.011 15.5 0.3 0.043 13.5 0.2 2.0 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Baculo_p74 PF04583.7 EDO08560.1 - 0.016 14.3 0.4 0.71 9.0 0.0 2.4 2 0 0 2 2 2 0 Baculoviridae p74 conserved region AAA_16 PF13191.1 EDO08560.1 - 0.022 14.7 0.0 0.085 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 EDO08560.1 - 0.053 14.0 0.0 0.17 12.3 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 EDO08560.1 - 0.07 12.4 0.5 11 5.3 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Ribosomal_S3Ae PF01015.13 EDO08560.1 - 0.6 9.4 4.1 0.59 9.4 0.8 2.3 2 0 0 2 2 2 0 Ribosomal S3Ae family ubiquitin PF00240.18 EDO08561.1 - 4.6e-28 96.4 1.8 1.9e-27 94.4 1.4 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EDO08561.1 - 1.5e-13 50.1 3.0 3.2e-13 49.1 2.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDO08561.1 - 3.2e-05 24.1 1.9 0.00017 21.7 0.6 2.4 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EDO08561.1 - 0.00039 20.2 0.4 0.0011 18.8 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDO08561.1 - 0.0076 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TrbI_Ftype PF09677.5 EDO08561.1 - 0.053 13.3 0.1 0.087 12.6 0.1 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) DUF1669 PF07894.7 EDO08561.1 - 0.085 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) GABP-alpha PF11620.3 EDO08561.1 - 0.22 11.5 3.2 0.23 11.4 0.8 1.9 1 1 1 2 2 2 0 GA-binding protein alpha chain Mito_carr PF00153.22 EDO08562.1 - 1.3e-65 217.1 5.0 7.3e-24 83.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Hydrolase_like2 PF13246.1 EDO08562.1 - 0.035 14.0 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Peptidase_C1 PF00112.18 EDO08563.1 - 7.5e-56 189.4 0.0 1.1e-55 188.8 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EDO08563.1 - 3.9e-13 49.4 8.1 2.6e-11 43.6 5.1 2.4 2 0 0 2 2 2 2 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EDO08563.1 - 2.3e-07 29.7 0.1 2.3e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Pkinase PF00069.20 EDO08564.1 - 5.8e-60 202.6 0.0 8.6e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO08564.1 - 5.3e-36 124.0 0.0 7.7e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO08564.1 - 9e-05 21.5 0.1 0.0063 15.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EDO08564.1 - 0.00041 20.1 1.2 0.31 10.7 0.1 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Y1_Tnp PF01797.11 EDO08565.1 - 0.053 13.3 0.1 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Transposase IS200 like S4 PF01479.20 EDO08566.1 - 1.8e-09 36.8 0.1 4.5e-09 35.6 0.1 1.7 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EDO08566.1 - 0.09 12.3 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 S4 domain PseudoU_synth_2 PF00849.17 EDO08566.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA pseudouridylate synthase BCL9 PF11502.3 EDO08567.1 - 0.42 10.1 0.1 0.42 10.1 0.0 2.9 4 0 0 4 4 4 0 B-cell lymphoma 9 protein DNA_pol_B PF00136.16 EDO08568.1 - 4.4e-68 230.1 0.1 7.4e-68 229.4 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EDO08568.1 - 1.1e-21 77.0 1.9 3.5e-11 42.5 0.1 2.9 2 1 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EDO08568.1 - 1.6e-08 34.4 2.5 5e-08 32.8 1.7 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta PK PF00224.16 EDO08569.1 - 6.5e-88 294.6 0.3 2.9e-48 164.2 0.0 2.2 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.11 EDO08569.1 - 0.0034 16.9 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain Mic1 PF07035.7 EDO08571.1 - 7.5e-10 38.4 0.3 3.4e-09 36.2 0.5 1.9 2 0 0 2 2 2 1 Colon cancer-associated protein Mic1-like Stn1 PF10451.4 EDO08571.1 - 0.042 12.6 0.0 0.079 11.7 0.0 1.3 1 0 0 1 1 1 0 Telomere regulation protein Stn1 DUF1662 PF07878.6 EDO08572.1 - 0.055 13.2 1.0 0.38 10.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1662) LXG PF04740.7 EDO08572.1 - 0.093 12.5 2.5 0.1 12.4 0.0 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily Peripla_BP_6 PF13458.1 EDO08572.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein RAP PF08373.5 EDO08573.1 - 6.5e-18 64.2 0.4 1.5e-17 63.1 0.3 1.6 1 0 0 1 1 1 1 RAP domain DUF559 PF04480.7 EDO08573.1 - 0.0011 18.5 0.0 0.0028 17.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF559) Zeta_toxin PF06414.7 EDO08573.1 - 0.055 12.5 0.2 0.11 11.5 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin Asp_protease PF09668.5 EDO08575.1 - 8.5e-43 144.8 1.0 1.5e-42 144.0 0.7 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EDO08575.1 - 8.6e-10 38.9 0.1 2e-09 37.8 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 EDO08575.1 - 2e-08 33.5 0.0 4.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP PF00077.15 EDO08575.1 - 4.3e-08 32.9 0.2 1.7e-07 31.0 0.1 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EDO08575.1 - 1.7e-06 27.7 0.0 4.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 EDO08575.1 - 0.0067 15.7 1.2 0.041 13.2 0.0 2.4 3 0 0 3 3 3 1 Ty3 transposon peptidase Rad60-SLD PF11976.3 EDO08575.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDO08575.1 - 0.086 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain His_Phos_1 PF00300.17 EDO08578.1 - 4.1e-07 30.2 0.0 5.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) OHA PF14418.1 EDO08579.1 - 1.7e-22 78.7 0.0 3e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 OST-HTH Associated domain OST-HTH PF12872.2 EDO08579.1 - 2.2e-05 24.2 0.0 5.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain tRNA_bind PF01588.15 EDO08580.1 - 2.7e-26 91.2 0.0 4.3e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.20 EDO08580.1 - 1.1e-07 31.6 0.0 2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDO08580.1 - 1.2e-05 25.6 0.0 2.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDO08580.1 - 0.00087 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DEAD PF00270.24 EDO08581.1 - 3.3e-40 137.3 0.9 7.1e-40 136.2 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO08581.1 - 8.8e-29 99.2 0.3 6.4e-28 96.4 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO08581.1 - 0.00053 19.8 0.1 0.0023 17.7 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EDO08581.1 - 0.0012 18.5 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Helicase_RecD PF05127.9 EDO08581.1 - 0.0013 18.4 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Helicase DUF1253 PF06862.7 EDO08581.1 - 0.0017 16.8 0.4 0.49 8.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_30 PF13604.1 EDO08581.1 - 0.0052 16.3 0.0 0.013 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain tRNA-synt_1b PF00579.20 EDO08581.1 - 0.039 13.0 0.2 0.081 12.0 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) CMS1 PF14617.1 EDO08581.1 - 0.044 12.8 0.1 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit PhoH PF02562.11 EDO08581.1 - 0.057 12.6 0.1 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein FUSC-like PF12805.2 EDO08581.1 - 0.11 11.3 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS EGF_3 PF12947.2 EDO08582.1 - 0.033 14.1 6.0 0.1 12.6 4.2 1.8 1 0 0 1 1 1 0 EGF domain EGF_MSP1_1 PF12946.2 EDO08582.1 - 0.034 13.9 12.9 0.027 14.2 6.6 2.3 2 0 0 2 2 2 0 MSP1 EGF domain 1 EB PF01683.13 EDO08582.1 - 0.056 13.5 8.0 0.031 14.3 3.9 1.8 2 0 0 2 2 2 0 EB module EGF PF00008.22 EDO08582.1 - 0.13 12.2 5.6 0.37 10.7 3.9 1.8 1 0 0 1 1 1 0 EGF-like domain DER1 PF04511.10 EDO08583.1 - 5.7e-14 52.0 0.5 5.7e-14 52.0 0.3 1.0 1 0 0 1 1 1 1 Der1-like family Kelch_3 PF13415.1 EDO08584.1 - 1.6e-24 85.4 1.9 7.1e-06 26.0 0.0 6.3 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EDO08584.1 - 9.5e-22 76.5 0.0 6.6e-05 22.7 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 EDO08584.1 - 3.5e-21 74.6 6.8 1.7e-05 24.4 0.2 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EDO08584.1 - 5.4e-14 51.6 6.2 0.0067 16.5 0.0 5.8 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EDO08584.1 - 2.9e-10 39.4 2.2 7.7e-06 25.4 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EDO08584.1 - 3.1e-09 36.2 4.4 0.022 14.3 0.0 5.0 6 0 0 6 6 6 3 Kelch motif HATPase_c_3 PF13589.1 EDO08584.1 - 8.8e-09 35.1 0.0 2.3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDO08584.1 - 1e-05 25.2 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RAG2 PF03089.9 EDO08584.1 - 0.067 11.8 0.0 0.56 8.8 0.0 2.1 2 0 0 2 2 2 0 Recombination activating protein 2 Bul1_N PF04425.7 EDO08585.1 - 0.066 11.7 0.0 0.082 11.4 0.0 1.1 1 0 0 1 1 1 0 Bul1 N terminus SMC_N PF02463.14 EDO08586.1 - 4.9e-59 199.2 55.0 2.9e-58 196.6 38.1 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDO08586.1 - 3.8e-23 81.7 2.1 1.6e-21 76.4 0.0 2.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EDO08586.1 - 7e-12 45.9 16.9 5.8e-07 29.7 1.0 3.9 3 2 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EDO08586.1 - 3.9e-11 43.6 21.7 3.9e-11 43.6 15.1 8.2 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.1 EDO08586.1 - 6e-07 28.8 0.0 1.6e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain TMF_DNA_bd PF12329.3 EDO08586.1 - 0.0042 16.8 4.2 0.0042 16.8 2.9 11.5 5 3 6 12 12 12 1 TATA element modulatory factor 1 DNA binding HSBP1 PF06825.7 EDO08586.1 - 0.028 14.0 0.1 0.028 14.0 0.1 7.3 7 1 0 7 7 7 0 Heat shock factor binding protein 1 Reo_sigmaC PF04582.7 EDO08586.1 - 0.03 13.5 33.0 0.052 12.7 3.1 4.9 2 2 1 4 4 4 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EDO08586.1 - 0.21 11.8 0.0 0.21 11.8 0.0 6.1 5 2 1 6 6 6 0 ABC transporter O-ag_pol_Wzy PF14296.1 EDO08587.1 - 0.0024 16.5 0.1 0.0026 16.3 0.1 1.1 1 0 0 1 1 1 1 O-antigen polysaccharide polymerase Wzy MpPF26 PF07666.6 EDO08587.1 - 0.012 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 M penetrans paralogue family 26 TMEM154 PF15102.1 EDO08587.1 - 0.019 14.6 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family DUF979 PF06166.7 EDO08587.1 - 0.02 13.8 0.0 0.025 13.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF979) DUF2177 PF09945.4 EDO08587.1 - 0.084 12.8 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) MCM PF00493.18 EDO08590.1 - 5.2e-133 442.9 0.0 7.3e-133 442.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDO08590.1 - 1.2e-08 35.5 0.4 3.6e-08 33.9 0.1 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDO08590.1 - 0.00014 21.1 0.0 0.0005 19.3 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDO08590.1 - 0.00059 19.5 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EDO08590.1 - 0.014 15.7 0.0 0.093 13.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EDO08590.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RAP PF08373.5 EDO08591.1 - 1.2e-12 47.4 0.2 4.3e-12 45.6 0.2 2.0 2 0 0 2 2 2 1 RAP domain TetR_C_2 PF08361.6 EDO08591.1 - 0.014 15.3 0.0 0.052 13.4 0.0 1.9 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region DsrD PF08679.6 EDO08591.1 - 0.13 12.3 0.0 0.93 9.5 0.0 2.5 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) HUN PF08729.5 EDO08592.1 - 6.6e-12 45.1 5.8 1.4e-11 44.0 4.0 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain TfoX_N PF04993.8 EDO08593.1 - 0.15 11.8 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 TfoX N-terminal domain LSM PF01423.17 EDO08594.1 - 1.7e-15 56.2 0.1 2.1e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain AMP-binding PF00501.23 EDO08595.1 - 7.3e-67 225.5 0.0 1e-66 225.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme YIF1 PF03878.10 EDO08596.1 - 0.11 11.6 4.3 1.3 8.1 0.1 2.4 2 0 0 2 2 2 0 YIF1 DNA_pol_A_exo1 PF01612.15 EDO08598.1 - 1.5e-24 86.4 0.0 2.2e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2_2 PF12756.2 EDO08599.1 - 2e-29 101.6 2.4 2.7e-25 88.4 0.4 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EDO08599.1 - 0.002 18.1 14.9 0.01 15.9 0.6 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.6 EDO08599.1 - 0.09 12.4 7.8 2.2 8.0 1.0 2.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger BIR PF00653.16 EDO08599.1 - 0.1 13.0 3.2 1.7 9.1 0.5 3.3 3 1 1 4 4 4 0 Inhibitor of Apoptosis domain zf-BED PF02892.10 EDO08599.1 - 0.13 12.0 4.1 0.39 10.5 1.4 2.6 2 0 0 2 2 2 0 BED zinc finger DUF3456 PF11938.3 EDO08599.1 - 0.15 12.0 2.9 0.21 11.6 0.9 2.0 2 0 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP zf-FCS PF06467.9 EDO08599.1 - 0.31 10.7 3.8 1.2 8.8 0.3 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif NOA36 PF06524.7 EDO08599.1 - 5 6.2 8.1 0.57 9.3 2.4 1.7 2 0 0 2 2 2 0 NOA36 protein CTDII PF01556.13 EDO08601.1 - 1.4e-28 98.5 5.3 1.3e-18 66.6 0.1 3.5 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 EDO08601.1 - 1.2e-19 69.8 2.0 1.8e-19 69.1 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EDO08601.1 - 2.1e-11 43.6 13.6 4.2e-11 42.7 9.5 1.5 1 0 0 1 1 1 1 DnaJ central domain Transcrip_act PF04949.8 EDO08601.1 - 0.055 13.0 0.2 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Transcriptional activator Rep_fac-A_C PF08646.5 EDO08602.1 - 3.5e-32 111.1 0.7 6.1e-30 103.8 0.2 3.0 3 0 0 3 3 3 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 EDO08602.1 - 2.7e-13 49.5 0.4 2.8e-09 36.6 0.0 4.0 2 1 2 4 4 4 2 OB-fold nucleic acid binding domain KOW PF00467.24 EDO08603.1 - 0.09 12.5 1.2 0.18 11.5 0.8 1.5 1 0 0 1 1 1 0 KOW motif Ribosomal_L16 PF00252.13 EDO08604.1 - 2.6e-31 108.1 0.1 3.5e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e NAC PF01849.13 EDO08605.1 - 1.6e-19 69.1 0.0 2.9e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 NAC domain Ribosomal_L21e PF01157.13 EDO08606.1 - 6.8e-36 122.0 2.1 1e-35 121.4 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_replicase_B PF03431.8 EDO08606.1 - 0.15 10.2 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 RNA replicase, beta-chain Methyltransf_26 PF13659.1 EDO08607.1 - 8.1e-11 41.9 0.0 1.5e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO08607.1 - 1.3e-10 41.0 0.0 2.3e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO08607.1 - 1.8e-09 37.9 0.0 4.6e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO08607.1 - 3.2e-09 37.3 0.0 7.7e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDO08607.1 - 4.2e-08 32.6 0.0 6.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EDO08607.1 - 1.4e-06 28.5 0.0 2.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EDO08607.1 - 6.9e-06 25.2 0.0 1.2e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.9 EDO08607.1 - 8.9e-06 25.1 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EDO08607.1 - 3.3e-05 24.2 0.0 8e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO08607.1 - 5.3e-05 22.9 0.0 0.00012 21.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EDO08607.1 - 0.0004 19.1 0.0 0.00081 18.1 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.4 EDO08607.1 - 0.00082 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 EDO08607.1 - 0.0044 16.2 0.0 0.0069 15.5 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.15 EDO08607.1 - 0.0045 16.1 0.0 0.0064 15.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.11 EDO08607.1 - 0.0045 16.6 0.0 0.0068 16.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EDO08607.1 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_3 PF01596.12 EDO08607.1 - 0.02 13.9 0.0 0.041 12.9 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_32 PF13679.1 EDO08607.1 - 0.039 13.6 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EDO08607.1 - 0.055 12.5 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EDO08607.1 - 0.091 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-CCCH PF00642.19 EDO08608.1 - 4e-08 32.7 15.6 1.6e-05 24.4 0.4 3.6 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Las1 PF04031.8 EDO08610.1 - 4.6e-37 127.0 0.2 5.2e-37 126.8 0.1 1.0 1 0 0 1 1 1 1 Las1-like Vma12 PF11712.3 EDO08611.1 - 0.017 14.8 0.3 0.03 14.0 0.2 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ribosomal_L7Ae PF01248.21 EDO08612.1 - 2.4e-21 75.0 1.5 3.8e-21 74.4 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EDO08612.1 - 0.0014 18.4 0.1 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit Pop3 Ribosomal_L18p PF00861.17 EDO08613.1 - 2.3e-38 131.0 0.1 2.3e-38 131.0 0.1 1.6 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EDO08613.1 - 2.3e-33 114.6 5.4 4.6e-33 113.6 3.7 1.5 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region EAL PF00563.15 EDO08613.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 EAL domain ECR1_N PF14382.1 EDO08614.1 - 2e-09 36.5 0.0 4.8e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 EDO08614.1 - 0.055 13.5 0.1 0.54 10.3 0.0 2.4 3 0 0 3 3 3 0 S1 RNA binding domain Ribosomal_L29e PF01779.12 EDO08615.1 - 2.2e-20 72.2 11.6 2.2e-20 72.2 8.0 1.4 2 0 0 2 2 2 1 Ribosomal L29e protein family Gemini_AL2 PF01440.11 EDO08615.1 - 0.21 11.6 1.9 0.22 11.6 1.3 1.1 1 0 0 1 1 1 0 Geminivirus AL2 protein zf-C2H2_jaz PF12171.3 EDO08615.1 - 0.35 11.0 0.2 0.35 11.0 0.1 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Peptidase_C12 PF01088.16 EDO08616.1 - 2.9e-45 154.0 0.0 1.3e-44 151.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Methyltransf_22 PF13383.1 EDO08618.1 - 0.0091 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ENTH PF01417.15 EDO08618.1 - 0.024 14.5 0.1 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 ENTH domain Cnd1 PF12717.2 EDO08618.1 - 0.04 13.7 1.4 1 9.2 0.1 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Ribosomal_L27e PF01777.13 EDO08620.1 - 3.1e-29 100.9 3.0 4.1e-29 100.5 2.1 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EDO08620.1 - 9.5e-05 21.9 1.0 0.0002 20.9 0.7 1.7 1 1 0 1 1 1 1 KOW motif Virulence_fact PF13769.1 EDO08620.1 - 0.13 12.1 0.2 2.7 7.9 0.1 2.2 2 1 0 2 2 2 0 Virulence factor zf-SNAP50_C PF12251.3 EDO08621.1 - 8.6e-60 201.4 1.7 1.2e-59 200.9 1.2 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Myb_DNA-bind_6 PF13921.1 EDO08622.1 - 0.0011 19.0 0.9 0.0023 17.9 0.2 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Pep3_Vps18 PF05131.9 EDO08623.1 - 4.4e-23 81.3 0.0 8.6e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.4 EDO08623.1 - 1.3e-05 25.3 0.2 2.8e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 EDO08623.1 - 0.00022 20.9 6.9 0.0019 18.0 4.9 2.5 1 1 1 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EDO08623.1 - 0.0009 19.3 0.9 0.0034 17.4 0.2 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDO08623.1 - 0.013 15.1 0.9 0.038 13.6 0.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO08623.1 - 0.026 14.2 5.9 0.1 12.3 4.1 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 EDO08623.1 - 0.034 13.9 0.0 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EDO08623.1 - 0.31 11.1 4.2 0.3 11.1 0.8 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GDI PF00996.13 EDO08624.1 - 0.072 11.3 0.0 0.1 10.8 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor TctB PF07331.6 EDO08625.1 - 1.9e-06 27.5 7.8 3.5e-06 26.7 5.4 1.4 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family DctQ PF04290.7 EDO08625.1 - 0.00017 21.3 6.8 0.00057 19.6 0.2 2.4 2 0 0 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component Tetraspannin PF00335.15 EDO08625.1 - 0.0094 15.2 11.2 0.0094 15.2 7.8 1.6 1 1 0 1 1 1 1 Tetraspanin family CopD PF05425.8 EDO08625.1 - 0.01 16.0 6.0 0.019 15.1 0.0 2.4 2 1 0 2 2 2 0 Copper resistance protein D PepSY_TM_2 PF13703.1 EDO08625.1 - 0.029 14.5 2.3 0.11 12.7 0.1 2.4 2 0 0 2 2 2 0 PepSY-associated TM helix MscS_TM PF12794.2 EDO08625.1 - 0.042 12.4 0.2 0.042 12.4 0.1 1.9 1 1 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Sensor PF13796.1 EDO08625.1 - 0.043 13.4 0.3 0.043 13.4 0.2 2.7 2 1 1 3 3 3 0 Putative sensor UPF0182 PF03699.8 EDO08625.1 - 0.051 11.5 2.6 0.058 11.3 1.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Lung_7-TM_R PF06814.8 EDO08625.1 - 0.069 12.0 5.9 0.1 11.4 4.1 1.2 1 0 0 1 1 1 0 Lung seven transmembrane receptor Cytochrom_B_N PF00033.14 EDO08625.1 - 0.095 12.0 5.2 0.2 10.9 3.6 1.6 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Cation_ATPase_C PF00689.16 EDO08625.1 - 0.13 11.8 9.9 0.098 12.1 5.9 1.5 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF3112 PF11309.3 EDO08625.1 - 0.36 10.6 7.5 0.19 11.4 3.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) Sugar_tr PF00083.19 EDO08625.1 - 0.86 8.1 12.3 1.2 7.6 8.5 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Ni_hydr_CYTB PF01292.15 EDO08625.1 - 1.5 8.1 5.9 1.7 7.9 0.5 2.3 1 1 2 3 3 3 0 Prokaryotic cytochrome b561 DUF4131 PF13567.1 EDO08625.1 - 1.6 8.0 7.6 0.14 11.5 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF202 PF02656.10 EDO08625.1 - 5.6 7.2 6.9 1.1e+02 3.1 4.7 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) MpPF26 PF07666.6 EDO08625.1 - 5.8 6.8 15.3 2.1 8.2 8.1 2.1 2 1 0 2 2 2 0 M penetrans paralogue family 26 DUF805 PF05656.9 EDO08625.1 - 6.3 6.6 13.8 0.81 9.5 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF805) DXPR_C PF13288.1 EDO08626.1 - 5e-37 126.6 0.0 8.4e-37 125.8 0.0 1.4 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_reductoisom PF02670.11 EDO08626.1 - 4.5e-34 117.7 0.1 7.7e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.7 EDO08626.1 - 1.1e-33 114.9 0.2 2.7e-27 94.4 0.0 2.8 2 0 0 2 2 2 2 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal Usp PF00582.21 EDO08626.1 - 0.006 16.7 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Universal stress protein family FAD_binding_2 PF00890.19 EDO08626.1 - 0.019 13.8 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain AAA_13 PF13166.1 EDO08629.1 - 0.00011 20.8 32.7 0.00044 18.8 9.7 2.2 1 1 1 2 2 2 2 AAA domain BRE1 PF08647.6 EDO08629.1 - 0.00011 22.0 2.4 0.00011 22.0 1.7 4.7 1 1 3 4 4 4 1 BRE1 E3 ubiquitin ligase Reo_sigmaC PF04582.7 EDO08629.1 - 0.00016 20.9 14.0 0.0028 16.9 1.6 2.9 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Tropomyosin PF00261.15 EDO08629.1 - 0.00021 20.4 40.0 0.00094 18.3 5.2 3.2 2 1 1 3 3 3 2 Tropomyosin CENP-F_leu_zip PF10473.4 EDO08629.1 - 0.00095 19.0 11.9 0.00095 19.0 8.2 4.1 2 1 2 4 4 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.6 EDO08629.1 - 0.00098 18.5 1.4 0.00098 18.5 1.0 5.1 1 1 4 5 5 5 2 Phage minor structural protein GP20 Spc7 PF08317.6 EDO08629.1 - 0.0025 16.5 41.9 0.007 15.0 11.3 3.2 1 1 2 3 3 3 3 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 EDO08629.1 - 0.0028 17.4 0.4 0.0028 17.4 0.3 5.4 1 1 4 5 5 5 1 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EDO08629.1 - 0.0095 15.8 10.5 0.0095 15.8 7.3 5.0 1 1 5 6 6 5 3 Afadin- and alpha -actinin-Binding GAS PF13851.1 EDO08629.1 - 0.011 14.9 43.2 0.075 12.2 10.5 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 EDO08629.1 - 0.019 14.8 49.2 0.028 14.2 11.8 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 EDO08629.1 - 0.022 12.5 49.7 0.028 12.1 15.9 2.5 1 1 1 2 2 2 0 Myosin tail Tropomyosin_1 PF12718.2 EDO08629.1 - 0.065 13.0 47.0 0.046 13.5 4.9 3.7 1 1 2 3 3 3 0 Tropomyosin like IncA PF04156.9 EDO08629.1 - 0.088 12.3 55.8 0.42 10.1 9.8 3.5 1 1 2 3 3 3 0 IncA protein APG6 PF04111.7 EDO08629.1 - 0.35 9.8 48.0 0.079 11.9 9.5 3.3 1 1 2 3 3 3 0 Autophagy protein Apg6 CCDC155 PF14662.1 EDO08629.1 - 0.51 9.9 52.3 3.3 7.2 14.7 3.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 MCPsignal PF00015.16 EDO08629.1 - 0.7 9.4 22.4 0.28 10.6 6.5 2.7 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3584 PF12128.3 EDO08629.1 - 1.6 5.9 50.9 0.33 8.2 16.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) EzrA PF06160.7 EDO08629.1 - 3.7 5.6 37.9 1.6e+02 0.2 26.3 2.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Sec8_exocyst PF04048.9 EDO08629.1 - 4.4 6.9 27.5 0.26 10.8 2.1 3.9 1 1 0 3 3 3 0 Sec8 exocyst complex component specific domain TPR_MLP1_2 PF07926.7 EDO08629.1 - 5.5 6.7 46.5 3.2 7.4 7.2 3.8 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein FYVE PF01363.16 EDO08630.1 - 6e-07 29.2 10.1 1.5e-06 28.0 7.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger GAS PF13851.1 EDO08630.1 - 0.0031 16.7 5.2 0.023 13.8 1.7 2.3 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF812 PF05667.6 EDO08630.1 - 0.0046 15.5 7.8 0.0061 15.1 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF2353 PF09789.4 EDO08630.1 - 0.0048 16.1 3.3 0.0048 16.1 2.3 1.8 2 1 1 3 3 3 1 Uncharacterized coiled-coil protein (DUF2353) Troponin PF00992.15 EDO08630.1 - 0.037 14.0 0.8 0.037 14.0 0.5 2.0 2 0 0 2 2 2 0 Troponin WEMBL PF05701.6 EDO08630.1 - 0.042 12.3 7.3 0.019 13.4 0.8 2.1 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DUF1664 PF07889.7 EDO08630.1 - 0.043 13.6 1.2 0.19 11.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 EDO08630.1 - 0.094 13.1 6.2 0.095 13.1 1.3 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Laminin_II PF06009.7 EDO08630.1 - 0.097 12.4 3.0 0.11 12.2 0.9 1.8 2 0 0 2 2 2 0 Laminin Domain II NPV_P10 PF05531.7 EDO08630.1 - 0.21 11.8 3.1 1.2 9.4 0.5 2.7 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 EDO08630.1 - 0.29 10.1 9.0 0.12 11.3 2.1 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 EDO08630.1 - 0.34 11.0 3.6 0.46 10.6 0.3 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MitMem_reg PF13012.1 EDO08630.1 - 0.4 10.7 5.3 0.49 10.4 0.6 2.7 1 1 0 2 2 2 0 Maintenance of mitochondrial structure and function PilJ PF13675.1 EDO08630.1 - 0.62 10.3 8.4 0.37 11.1 4.1 1.8 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Seryl_tRNA_N PF02403.17 EDO08630.1 - 0.93 9.5 6.0 0.24 11.4 1.2 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-H PF05837.7 EDO08630.1 - 1.1 9.4 11.8 3 8.0 2.8 3.0 2 1 1 3 3 3 0 Centromere protein H (CENP-H) CENP-F_leu_zip PF10473.4 EDO08630.1 - 3.2 7.6 11.1 3.4 7.5 3.7 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.3 EDO08630.1 - 3.5 6.9 13.0 0.46 9.8 6.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Rootletin PF15035.1 EDO08630.1 - 3.8 7.4 19.8 0.5 10.3 8.2 2.4 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.3 EDO08630.1 - 3.9 7.2 13.2 1.7 8.3 2.6 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Fzo_mitofusin PF04799.8 EDO08630.1 - 5.3 6.3 6.5 4.2 6.7 2.1 2.0 2 0 0 2 2 2 0 fzo-like conserved region GrpE PF01025.14 EDO08630.1 - 10 5.6 8.5 3.6 7.0 0.3 2.6 2 1 0 2 2 2 0 GrpE RRM_1 PF00076.17 EDO08631.1 - 2.2e-06 27.1 0.0 3.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDO08631.1 - 0.0008 19.2 0.1 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif RRM_6 PF14259.1 EDO08631.1 - 0.0023 17.8 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EDO08631.1 - 0.02 14.6 16.3 0.023 14.4 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) PRP38_assoc PF12871.2 EDO08631.1 - 0.093 13.2 26.2 0.16 12.5 18.1 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term TB2_DP1_HVA22 PF03134.14 EDO08632.1 - 3.5e-17 61.9 7.9 7.3e-16 57.6 5.5 2.2 1 1 0 1 1 1 1 TB2/DP1, HVA22 family Sulfate_tra_GLY PF13792.1 EDO08632.1 - 0.063 12.9 1.8 0.11 12.2 1.3 1.4 1 0 0 1 1 1 0 Sulfate transporter N-terminal domain with GLY motif Ribosomal_S8 PF00410.14 EDO08633.1 - 6.7e-23 80.9 0.0 8.4e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Nuf2 PF03800.9 EDO08634.1 - 3.9e-32 111.2 2.8 3.9e-32 111.2 0.0 2.4 2 1 1 3 3 3 1 Nuf2 family Flg_hook PF02120.11 EDO08634.1 - 0.035 13.7 2.7 0.11 12.1 1.9 1.8 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Filament PF00038.16 EDO08634.1 - 0.31 10.4 38.3 0.95 8.8 26.5 1.9 1 1 0 1 1 1 0 Intermediate filament protein HOOK PF05622.7 EDO08634.1 - 0.57 7.9 43.1 0.077 10.8 16.9 2.0 1 1 1 2 2 2 0 HOOK protein DUF1664 PF07889.7 EDO08634.1 - 1.1 9.0 24.9 0.14 11.9 1.0 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) ATP-synt_B PF00430.13 EDO08634.1 - 2.6 7.8 33.4 0.055 13.2 9.4 4.0 3 1 1 4 4 4 0 ATP synthase B/B' CF(0) KxDL PF10241.4 EDO08634.1 - 3.4 7.6 21.5 0.78 9.6 0.2 4.4 2 1 3 5 5 5 0 Uncharacterized conserved protein Pyrophosphatase PF00719.14 EDO08636.1 - 1.4e-51 174.0 0.0 1.7e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Spc97_Spc98 PF04130.8 EDO08637.1 - 7.5e-11 41.0 2.4 0.0013 17.1 0.3 3.2 3 0 0 3 3 3 3 Spc97 / Spc98 family CS PF04969.11 EDO08638.1 - 0.061 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 CS domain NMT PF01233.14 EDO08639.1 - 4.8e-75 250.6 0.0 7.2e-75 250.0 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EDO08639.1 - 5.6e-67 224.8 3.9 9.9e-67 224.0 2.7 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EDO08639.1 - 0.0053 16.6 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Phage_portal_2 PF05136.8 EDO08639.1 - 0.023 13.2 0.0 0.034 12.6 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family Acetyltransf_7 PF13508.1 EDO08639.1 - 0.098 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA PF00004.24 EDO08640.1 - 1.1e-78 261.7 0.0 3.8e-46 156.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDO08640.1 - 2e-09 36.8 0.0 0.00094 18.2 0.0 3.1 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EDO08640.1 - 1.6e-08 34.4 0.1 0.0013 18.4 0.0 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO08640.1 - 1.9e-08 34.5 0.0 0.0044 17.0 0.0 3.5 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EDO08640.1 - 2.6e-08 34.0 0.0 0.0029 17.7 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EDO08640.1 - 3.7e-08 33.4 0.0 0.0021 17.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EDO08640.1 - 3e-07 30.5 0.0 0.0075 16.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.7 EDO08640.1 - 3.1e-07 29.6 0.0 0.0023 17.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 EDO08640.1 - 6.4e-07 29.3 0.0 0.022 14.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EDO08640.1 - 1e-06 27.7 0.0 0.011 14.4 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.16 EDO08640.1 - 3.2e-06 26.4 0.1 0.012 14.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EDO08640.1 - 8.7e-06 26.5 0.0 0.034 14.9 0.0 3.8 4 0 0 4 4 2 1 AAA domain Sigma54_activ_2 PF14532.1 EDO08640.1 - 2.5e-05 24.3 0.0 0.074 13.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EDO08640.1 - 3.6e-05 23.5 0.1 0.069 12.8 0.0 3.9 2 2 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 EDO08640.1 - 5.6e-05 22.6 0.0 0.25 10.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 EDO08640.1 - 0.00022 20.9 0.0 0.023 14.3 0.0 3.3 3 1 0 3 3 3 1 NACHT domain AAA_24 PF13479.1 EDO08640.1 - 0.00028 20.5 0.2 0.04 13.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EDO08640.1 - 0.0004 19.5 0.4 3.1 6.8 0.0 3.6 3 1 1 4 4 4 2 KaiC DUF815 PF05673.8 EDO08640.1 - 0.00063 18.7 0.0 0.13 11.1 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EDO08640.1 - 0.001 19.0 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDO08640.1 - 0.0011 18.4 0.3 1.4 8.3 0.0 3.5 2 1 1 3 3 3 1 AAA domain ABC_tran PF00005.22 EDO08640.1 - 0.0015 18.8 0.0 0.17 12.1 0.0 2.6 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 EDO08640.1 - 0.0015 18.0 0.0 0.72 9.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 EDO08640.1 - 0.002 18.0 0.1 1.8 8.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EDO08640.1 - 0.0024 17.5 0.2 1.1 9.0 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain Bac_DnaA PF00308.13 EDO08640.1 - 0.0038 16.9 0.0 0.16 11.5 0.0 3.2 2 1 0 2 2 2 1 Bacterial dnaA protein NB-ARC PF00931.17 EDO08640.1 - 0.0042 15.9 0.0 0.3 9.8 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.10 EDO08640.1 - 0.0042 15.8 0.0 1.7 7.2 0.0 2.4 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 EDO08640.1 - 0.0063 16.8 0.0 0.083 13.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_11 PF13086.1 EDO08640.1 - 0.0074 15.8 0.2 0.78 9.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain KAP_NTPase PF07693.9 EDO08640.1 - 0.0086 15.1 0.0 0.024 13.6 0.0 1.7 2 0 0 2 2 1 1 KAP family P-loop domain ATP-synt_ab PF00006.20 EDO08640.1 - 0.0089 15.5 0.0 2.8 7.3 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Parvo_NS1 PF01057.12 EDO08640.1 - 0.016 14.0 0.0 0.42 9.4 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 EDO08640.1 - 0.026 14.1 0.0 4.1 7.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.6 EDO08640.1 - 0.04 12.6 0.0 0.075 11.7 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain AFG1_ATPase PF03969.11 EDO08640.1 - 0.14 10.9 0.0 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase UPF0079 PF02367.12 EDO08640.1 - 0.14 11.7 0.0 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DS PF01916.12 EDO08641.1 - 1.8e-125 417.9 0.0 2.1e-125 417.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Actin PF00022.14 EDO08642.1 - 2.7e-106 355.3 0.0 4.3e-106 354.6 0.0 1.3 1 1 0 1 1 1 1 Actin PIP5K PF01504.13 EDO08643.1 - 8.4e-52 175.7 0.0 1.7e-51 174.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EDO08643.1 - 4.2e-10 38.8 0.0 9.8e-10 37.6 0.0 1.5 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PIR PF00399.14 EDO08643.1 - 0.16 11.3 1.3 0.3 10.5 0.9 1.5 1 0 0 1 1 1 0 Yeast PIR protein repeat NTF2 PF02136.15 EDO08645.1 - 8.7e-25 87.4 0.0 9.7e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Pro_isomerase PF00160.16 EDO08646.1 - 2.9e-41 141.2 0.1 3.7e-41 140.9 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_TL5_C PF14693.1 EDO08647.1 - 0.018 15.2 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein TL5, C-terminal domain Cuticle_2 PF08184.6 EDO08647.1 - 0.055 13.2 0.1 6.8 6.5 0.0 3.0 3 0 0 3 3 3 0 Cuticle protein 7 isoform family Aminotran_1_2 PF00155.16 EDO08648.1 - 1.4e-50 172.3 0.0 1.6e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II COX5B PF01215.14 EDO08649.1 - 1.2e-12 47.7 0.0 1.8e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Histone PF00125.19 EDO08650.1 - 7.4e-14 51.6 1.3 3e-13 49.6 0.1 2.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 UPF0061 PF02696.9 EDO08650.1 - 0.017 13.4 0.8 0.027 12.8 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family Metallophos PF00149.23 EDO08651.1 - 4.4e-41 140.4 0.2 5.5e-41 140.1 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SLBP_RNA_bind PF15247.1 EDO08652.1 - 1.1e-20 73.1 0.5 1.1e-20 73.1 0.4 2.0 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain tRNA-synt_2b PF00587.20 EDO08653.1 - 6.9e-24 84.3 0.3 1.1e-23 83.6 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDO08653.1 - 1.5e-05 24.8 0.0 3.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EDO08653.1 - 0.016 14.0 0.5 0.043 12.5 0.3 1.7 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) Hist_deacetyl PF00850.14 EDO08654.1 - 3.5e-75 253.1 0.2 4.7e-75 252.7 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Yippee-Mis18 PF03226.9 EDO08655.1 - 1e-18 67.1 0.2 1.3e-18 66.7 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.4 EDO08655.1 - 0.0026 16.5 1.0 0.42 9.2 0.1 2.0 1 1 1 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding GFA PF04828.9 EDO08655.1 - 0.009 15.9 2.2 0.75 9.7 0.1 2.2 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme RIG-I_C-RD PF11648.3 EDO08655.1 - 0.016 15.0 0.3 0.045 13.6 0.2 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I Nudix_N_2 PF14803.1 EDO08655.1 - 0.017 14.7 1.5 1.7 8.4 0.1 3.0 3 0 0 3 3 3 0 Nudix N-terminal LIM PF00412.17 EDO08655.1 - 0.021 14.9 1.4 2 8.5 0.0 2.7 2 1 1 3 3 3 0 LIM domain DZR PF12773.2 EDO08655.1 - 0.055 13.3 1.3 0.62 9.9 0.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EDO08655.1 - 0.069 12.3 0.4 4.8 6.5 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-CHY PF05495.7 EDO08655.1 - 0.082 13.0 0.4 1.9 8.6 0.1 2.1 2 0 0 2 2 2 0 CHY zinc finger zinc_ribbon_6 PF14599.1 EDO08655.1 - 0.097 12.4 0.9 0.62 9.8 0.0 2.1 2 0 0 2 2 2 0 Zinc-ribbon Ribosomal_S27e PF01667.12 EDO08655.1 - 0.13 11.7 1.1 4.9 6.7 0.0 2.7 3 0 0 3 3 3 0 Ribosomal protein S27 C1_4 PF07975.7 EDO08655.1 - 0.16 12.0 1.7 3 7.9 0.2 2.2 2 0 0 2 2 2 0 TFIIH C1-like domain Avian_gp85 PF03708.9 EDO08655.1 - 0.4 9.8 4.4 2.8 7.1 1.0 2.0 1 1 1 2 2 2 0 Avian retrovirus envelope protein, gp85 Zn_Tnp_IS1595 PF12760.2 EDO08655.1 - 0.95 9.3 3.5 6.3 6.6 0.4 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Thioredoxin PF00085.15 EDO08656.1 - 6.8e-19 67.4 0.2 8.3e-19 67.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EDO08656.1 - 0.00058 19.9 0.0 0.0015 18.6 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EDO08656.1 - 0.011 15.8 0.1 0.04 14.1 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.19 EDO08656.1 - 0.016 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Redoxin PF08534.5 EDO08656.1 - 0.022 14.3 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Redoxin DUF953 PF06110.6 EDO08656.1 - 0.031 13.7 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.1 EDO08656.1 - 0.052 13.5 0.2 0.1 12.6 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.1 EDO08656.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain V-ATPase_C PF03223.10 EDO08657.1 - 1.8e-81 273.9 0.7 2.2e-81 273.6 0.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C HECT PF00632.20 EDO08662.1 - 2.2e-86 289.8 0.0 4.7e-86 288.8 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) LRR_4 PF12799.2 EDO08663.1 - 0.22 11.1 10.6 2.5 7.8 0.1 5.1 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EDO08663.1 - 7.5 7.0 20.8 26 5.3 0.1 6.8 7 1 0 7 7 7 0 Leucine Rich Repeat RPA_C PF08784.6 EDO08664.1 - 0.029 14.7 0.6 0.07 13.5 0.4 1.8 1 1 0 1 1 1 0 Replication protein A C terminal Telomere_reg-2 PF10193.4 EDO08665.1 - 0.0073 16.5 1.8 0.015 15.5 0.0 2.5 3 0 0 3 3 3 1 Telomere length regulation protein IF4E PF01652.13 EDO08667.1 - 3e-41 140.7 0.0 4e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ABC_tran PF00005.22 EDO08669.1 - 2.2e-37 128.4 0.0 6.7e-37 126.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EDO08669.1 - 7.3e-29 101.0 4.0 1e-28 100.5 2.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EDO08669.1 - 1e-06 28.1 1.0 4.1e-05 22.9 0.3 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDO08669.1 - 6.3e-05 23.0 0.1 0.048 13.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDO08669.1 - 0.00018 22.3 0.1 0.00052 20.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 EDO08669.1 - 0.0015 18.0 0.1 0.0073 15.8 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 EDO08669.1 - 0.0037 17.2 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EDO08669.1 - 0.0039 16.9 0.1 0.097 12.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EDO08669.1 - 0.004 16.5 0.0 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EDO08669.1 - 0.0067 16.2 0.1 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EDO08669.1 - 0.0071 16.4 0.4 0.051 13.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EDO08669.1 - 0.0074 15.7 0.3 0.019 14.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 EDO08669.1 - 0.0087 16.2 0.1 0.16 12.1 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EDO08669.1 - 0.013 14.4 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 EDO08669.1 - 0.013 14.9 0.1 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 EDO08669.1 - 0.017 15.4 0.2 0.044 14.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDO08669.1 - 0.024 14.9 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EDO08669.1 - 0.029 14.2 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.1 EDO08669.1 - 0.043 13.7 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EDO08669.1 - 0.044 12.9 0.1 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 EDO08669.1 - 0.071 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RecA PF00154.16 EDO08669.1 - 0.085 11.9 0.1 0.19 10.7 0.0 1.6 2 0 0 2 2 1 0 recA bacterial DNA recombination protein AAA_30 PF13604.1 EDO08669.1 - 0.091 12.3 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EDO08669.1 - 0.095 12.4 0.1 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EDO08669.1 - 0.12 12.1 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EDO08669.1 - 0.16 11.8 0.7 1.1 9.0 0.2 2.3 1 1 1 2 2 2 0 AAA domain SbcCD_C PF13558.1 EDO08669.1 - 0.21 11.5 1.5 3 7.8 0.4 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit WD40 PF00400.27 EDO08670.1 - 8.3e-51 168.1 28.7 1.7e-10 40.3 0.4 11.3 12 0 0 12 12 12 8 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EDO08670.1 - 5.2e-07 28.7 3.2 0.3 9.7 0.2 5.4 2 2 2 5 5 5 4 Nup133 N terminal like Nup160 PF11715.3 EDO08670.1 - 3e-05 22.3 1.1 0.23 9.5 0.1 3.3 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Utp12 PF04003.7 EDO08670.1 - 0.0012 18.7 3.1 0.0032 17.3 1.9 1.9 2 0 0 2 2 2 1 Dip2/Utp12 Family Val_tRNA-synt_C PF10458.4 EDO08672.1 - 0.058 13.4 0.9 13 5.9 0.0 3.0 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Reo_sigmaC PF04582.7 EDO08672.1 - 0.089 11.9 1.2 0.14 11.2 0.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Med4 PF10018.4 EDO08672.1 - 0.29 10.5 5.0 0.67 9.3 3.5 1.6 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 SlyX PF04102.7 EDO08672.1 - 0.38 11.1 6.1 0.61 10.4 0.8 3.3 1 1 2 3 3 3 0 SlyX DUF3571 PF12095.3 EDO08672.1 - 1.2 9.4 10.8 2.1 8.6 0.3 4.6 3 1 2 5 5 5 0 Protein of unknown function (DUF3571) Phage_Gp23 PF10669.4 EDO08672.1 - 3.5 7.7 7.7 0.9 9.6 1.1 2.7 2 1 1 3 3 3 0 Protein gp23 (Bacteriophage A118) IncA PF04156.9 EDO08672.1 - 7.9 6.0 17.9 6.2 6.3 9.2 2.6 2 1 0 2 2 2 0 IncA protein Glycos_transf_2 PF00535.21 EDO08673.1 - 1.1e-30 106.6 0.0 1.3e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EDO08673.1 - 2e-15 57.1 0.0 2.5e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EDO08673.1 - 2e-07 30.4 0.0 3.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 EDO08673.1 - 6.4e-05 22.1 0.0 0.0043 16.1 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EDO08673.1 - 0.029 14.0 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 OTU PF02338.14 EDO08674.1 - 1.7e-09 38.2 0.3 1.7e-09 38.2 0.2 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EDO08674.1 - 1.3e-07 31.2 0.8 0.00017 21.0 0.0 2.0 1 1 1 2 2 2 2 Peptidase C65 Otubain NNMT_PNMT_TEMT PF01234.12 EDO08674.1 - 0.042 12.8 0.3 0.057 12.3 0.2 1.4 1 1 0 1 1 1 0 NNMT/PNMT/TEMT family DUF2533 PF10752.4 EDO08674.1 - 0.72 10.1 4.9 3.8 7.8 1.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2533) C1_1 PF00130.17 EDO08675.1 - 0.066 12.9 0.5 0.066 12.9 0.3 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NIF PF03031.13 EDO08676.1 - 5.6e-29 100.8 0.0 2.9e-28 98.5 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF43 PF01861.11 EDO08676.1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 DUF2608 PF11019.3 EDO08676.1 - 0.062 12.2 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) HAD_2 PF13419.1 EDO08676.1 - 0.098 12.8 0.0 0.49 10.6 0.0 2.0 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Methyltransf_16 PF10294.4 EDO08677.1 - 6.3e-24 84.3 0.1 1.1e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ank_2 PF12796.2 EDO08677.1 - 1.4e-11 44.5 0.5 3.2e-11 43.3 0.4 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDO08677.1 - 1.6e-09 37.6 4.1 0.00031 20.8 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO08677.1 - 2.1e-08 33.5 0.1 0.0035 17.4 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 EDO08677.1 - 2.2e-08 33.5 0.0 0.0018 18.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EDO08677.1 - 3.8e-06 27.2 1.6 0.017 15.5 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) tRNA-synt_2 PF00152.15 EDO08679.1 - 1.1e-66 224.8 0.0 3.1e-65 220.1 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDO08679.1 - 8.1e-08 32.0 0.0 1.7e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EDO08679.1 - 0.00032 19.9 0.1 0.003 16.7 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) MFS_1 PF07690.11 EDO08680.1 - 3e-19 68.9 27.5 4.7e-19 68.3 19.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Flavi_NS4A PF01350.12 EDO08680.1 - 9.7 5.7 9.2 0.26 10.8 0.1 2.7 3 0 0 3 3 3 0 Flavivirus non-structural protein NS4A SKN1 PF03935.10 EDO08687.1 - 0.073 11.2 0.1 0.1 10.7 0.0 1.1 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Chorein_N PF12624.2 EDO08691.1 - 6.2e-09 35.4 1.9 2.8e-08 33.3 0.2 3.0 3 0 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter zf-CCCH PF00642.19 EDO08692.1 - 0.035 13.7 3.0 0.035 13.7 2.1 4.3 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EDO08692.1 - 1.3 9.1 13.7 2 8.5 1.8 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type RNA_pol_A_bac PF01000.21 EDO08693.1 - 5.9e-05 23.2 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EDO08693.1 - 0.0016 17.5 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain VHS PF00790.14 EDO08695.1 - 0.061 12.9 0.2 7.4 6.1 0.0 2.6 1 1 0 2 2 2 0 VHS domain FUN14 PF04930.10 EDO08696.1 - 0.0001 22.5 3.6 0.00026 21.1 2.5 1.7 1 1 0 1 1 1 1 FUN14 family zf-B_box PF00643.19 EDO08698.1 - 8e-05 22.4 8.5 0.00019 21.2 5.9 1.6 1 0 0 1 1 1 1 B-box zinc finger Wx5_PLAF3D7 PF09688.5 EDO08698.1 - 0.00045 20.1 4.9 0.0005 20.0 2.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (Wx5_PLAF3D7) Baculo_PEP_C PF04513.7 EDO08698.1 - 0.0074 16.1 0.7 0.048 13.4 0.3 2.0 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.6 EDO08698.1 - 0.027 14.5 0.9 0.044 13.7 0.7 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Sec20 PF03908.8 EDO08698.1 - 0.048 13.3 0.5 0.12 12.0 0.4 1.7 1 0 0 1 1 1 0 Sec20 Bacillus_HBL PF05791.6 EDO08698.1 - 0.057 12.7 1.9 0.082 12.2 0.8 1.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Med9 PF07544.8 EDO08698.1 - 0.076 12.7 1.5 1.6 8.5 0.0 2.8 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4463 PF14703.1 EDO08698.1 - 0.076 13.5 0.7 9.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Exonuc_VII_L PF02601.10 EDO08698.1 - 0.26 10.4 3.4 0.33 10.0 2.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fzo_mitofusin PF04799.8 EDO08698.1 - 0.42 9.9 7.2 1 8.7 3.3 2.0 1 1 1 2 2 2 0 fzo-like conserved region FHA PF00498.21 EDO08699.1 - 9.5e-19 67.2 0.1 2e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 FHA domain PI3_PI4_kinase PF00454.22 EDO08700.1 - 2e-32 112.5 0.1 5.2e-32 111.1 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EDO08700.1 - 5.7e-10 38.4 0.0 2.1e-09 36.6 0.0 2.1 1 0 0 1 1 1 1 FATC domain TPR_14 PF13428.1 EDO08700.1 - 0.0013 19.1 0.4 18 6.3 0.0 4.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDO08700.1 - 0.018 14.9 1.6 0.81 9.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDO08700.1 - 0.043 14.1 0.2 19 5.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDO08700.1 - 0.23 12.1 3.3 6.9 7.4 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.8 EDO08701.1 - 1.4e-69 232.6 0.1 2e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Cyto_heme_lyase PF01265.12 EDO08702.1 - 6.4e-65 219.3 0.4 7.7e-65 219.0 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Isy1 PF06246.7 EDO08703.1 - 5.8e-75 251.9 0.5 6.6e-75 251.8 0.3 1.0 1 0 0 1 1 1 1 Isy1-like splicing family CRAL_TRIO PF00650.15 EDO08704.1 - 7.9e-34 116.4 0.0 1.2e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDO08704.1 - 1.3e-09 38.0 0.1 1.6e-08 34.5 0.1 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EDO08704.1 - 8.5e-08 32.2 0.1 1.7e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain WD40 PF00400.27 EDO08705.1 - 0.017 15.0 0.2 0.22 11.4 0.0 2.6 3 0 0 3 3 3 0 WD domain, G-beta repeat RNA_pol_A_bac PF01000.21 EDO08706.1 - 1.5e-27 95.9 0.0 2.8e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EDO08706.1 - 4e-15 54.6 0.0 7e-15 53.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.2 EDO08706.1 - 0.0043 17.4 0.3 0.011 16.1 0.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EDO08706.1 - 0.051 13.3 0.5 0.097 12.4 0.3 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 EDO08706.1 - 0.069 13.4 0.3 0.18 12.0 0.2 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain eIF-1a PF01176.14 EDO08707.1 - 5.1e-28 96.2 0.1 7.5e-28 95.7 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PCI PF01399.22 EDO08708.1 - 5.3e-12 45.9 0.3 2.6e-11 43.7 0.0 2.4 3 0 0 3 3 3 1 PCI domain Brr6_like_C_C PF10104.4 EDO08709.1 - 5.3e-39 132.8 1.5 7.9e-39 132.2 1.0 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Tcf25 PF04910.9 EDO08712.1 - 4e-64 216.8 0.1 6.7e-64 216.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PseudoU_synth_2 PF00849.17 EDO08713.1 - 2.3e-28 99.0 0.0 3.4e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Stk19 PF10494.4 EDO08713.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 DWNN PF08783.6 EDO08714.1 - 1.4e-13 50.5 0.1 2.8e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-C3HC4 PF00097.20 EDO08714.1 - 1.3 8.7 10.9 2.7 7.7 7.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO08714.1 - 3.3 7.4 10.7 6.7 6.4 7.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NIF PF03031.13 EDO08715.1 - 1.4e-31 109.3 0.2 2e-31 108.7 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Vps53_N PF04100.7 EDO08716.1 - 6e-64 216.1 2.8 6e-64 216.1 1.9 1.8 3 0 0 3 3 3 1 Vps53-like, N-terminal Apc4 PF12896.2 EDO08716.1 - 0.026 13.8 0.3 0.15 11.3 0.2 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 tRNA-synt_2c PF01411.14 EDO08717.1 - 4.8e-191 635.7 0.0 6.5e-191 635.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EDO08717.1 - 1.6e-11 43.8 0.2 4e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain WD40 PF00400.27 EDO08718.1 - 3.1e-06 26.8 0.3 0.00016 21.4 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF814 PF05670.8 EDO08719.1 - 3.9e-21 74.7 0.0 8.1e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) FbpA PF05833.6 EDO08719.1 - 0.0013 17.3 0.0 0.0032 16.0 0.0 1.7 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1508 PF07411.7 EDO08719.1 - 0.062 12.7 0.1 0.18 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) Pigment_DH PF06324.6 EDO08720.1 - 0.073 12.3 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) DUF4477 PF14780.1 EDO08721.1 - 0.033 13.5 1.8 0.066 12.5 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Telomere_reg-2 PF10193.4 EDO08721.1 - 0.06 13.6 5.4 0.36 11.1 0.8 2.6 2 0 0 2 2 2 0 Telomere length regulation protein DUF3373 PF11853.3 EDO08721.1 - 0.076 11.5 1.2 0.11 10.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF2762 PF10960.3 EDO08721.1 - 0.21 11.2 5.7 0.11 12.1 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) Seryl_tRNA_N PF02403.17 EDO08721.1 - 0.4 10.7 17.9 0.27 11.2 10.0 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FUSC PF04632.7 EDO08721.1 - 1.5 7.1 2.5 2.2 6.6 1.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.4 EDO08721.1 - 2.5 6.9 12.5 4 6.3 8.1 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EDO08722.1 - 0.00034 20.2 1.0 0.0015 18.1 0.3 1.9 2 0 0 2 2 2 1 IncA protein TMF_TATA_bd PF12325.3 EDO08722.1 - 0.0023 17.6 5.4 0.0023 17.6 3.7 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 EDO08722.1 - 0.0076 16.1 11.8 0.27 11.0 0.1 3.1 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 EDO08722.1 - 0.01 15.5 8.1 3.5 7.4 0.5 3.2 3 0 0 3 3 3 0 Prefoldin subunit Laminin_II PF06009.7 EDO08722.1 - 0.014 15.1 3.0 0.014 15.1 2.1 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF3166 PF11365.3 EDO08722.1 - 0.021 15.2 2.8 0.055 13.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Atg14 PF10186.4 EDO08722.1 - 0.034 13.0 5.0 0.032 13.1 1.9 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 HrcA PF01628.16 EDO08722.1 - 0.036 13.6 0.4 0.061 12.9 0.2 1.3 1 0 0 1 1 1 0 HrcA protein C terminal domain Seryl_tRNA_N PF02403.17 EDO08722.1 - 0.11 12.4 9.5 0.1 12.5 2.7 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 EDO08722.1 - 0.12 12.1 6.7 2.4 7.9 2.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) CCDC-167 PF15188.1 EDO08722.1 - 0.21 11.5 8.3 0.057 13.3 3.3 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4407 PF14362.1 EDO08722.1 - 0.25 10.2 2.7 0.45 9.4 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PEP-utilisers_N PF05524.8 EDO08722.1 - 0.43 10.3 2.5 2.5 7.8 0.5 2.5 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DivIC PF04977.10 EDO08722.1 - 0.52 9.8 5.2 4.1 6.9 0.1 3.0 3 0 0 3 3 3 0 Septum formation initiator Reo_sigmaC PF04582.7 EDO08722.1 - 0.62 9.1 2.6 3.7 6.6 0.6 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Allexi_40kDa PF05549.6 EDO08722.1 - 0.65 9.2 8.5 1 8.5 3.7 2.5 2 1 0 2 2 2 0 Allexivirus 40kDa protein AATF-Che1 PF13339.1 EDO08722.1 - 1 9.5 5.6 1.1 9.3 2.3 2.2 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF3618 PF12277.3 EDO08722.1 - 1.2 9.1 4.9 2 8.4 1.4 2.5 2 1 0 2 2 1 0 Protein of unknown function (DUF3618) DUF4200 PF13863.1 EDO08722.1 - 1.5 8.7 11.5 1.5 8.7 4.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Med21 PF11221.3 EDO08722.1 - 1.7 8.5 6.2 1.4 8.8 0.3 2.8 3 0 0 3 3 3 0 Subunit 21 of Mediator complex TBPIP PF07106.8 EDO08722.1 - 1.8 8.0 10.8 1.7 8.1 4.0 2.6 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc24 PF08286.6 EDO08722.1 - 2.2 8.0 16.2 2.4 7.8 1.1 3.4 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Snapin_Pallidin PF14712.1 EDO08722.1 - 2.5 8.4 7.1 1.5 9.2 2.8 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Adeno_PIX PF03955.9 EDO08722.1 - 2.9 8.4 4.6 2.9 8.4 1.8 2.0 2 1 0 2 2 1 0 Adenovirus hexon-associated protein (IX) Prefoldin PF02996.12 EDO08722.1 - 5.2 6.7 7.9 1.4 8.5 0.5 2.7 3 0 0 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.3 EDO08722.1 - 5.2 6.9 10.6 4.4 7.1 0.3 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding PCRF PF03462.13 EDO08722.1 - 6.8 6.4 7.3 8.9 6.0 0.4 2.6 2 1 0 3 3 2 0 PCRF domain NOA36 PF06524.7 EDO08722.1 - 6.8 5.8 7.3 8.3 5.5 5.0 1.3 1 0 0 1 1 1 0 NOA36 protein DUF1640 PF07798.6 EDO08722.1 - 7.8 6.5 10.9 1.6 8.7 4.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) HHH_5 PF14520.1 EDO08723.1 - 3.6e-09 36.6 0.0 7.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EDO08723.1 - 0.0069 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.18 EDO08723.1 - 0.035 13.8 0.5 0.12 12.1 0.0 2.1 3 0 0 3 3 3 0 Helix-hairpin-helix motif GCC2_GCC3 PF07699.8 EDO08725.1 - 3.7e-45 151.2 114.3 3e-08 33.0 3.3 12.5 11 1 1 12 12 12 10 GCC2 and GCC3 DASH_Spc34 PF08657.5 EDO08725.1 - 0.012 15.3 5.0 0.019 14.6 3.5 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 GCC2_GCC3 PF07699.8 EDO08726.1 - 4.8e-36 122.1 116.2 1e-08 34.6 1.0 12.6 12 1 1 13 13 13 10 GCC2 and GCC3 NYD-SP28 PF14772.1 EDO08726.1 - 0.074 13.1 4.1 0.15 12.1 2.8 1.5 1 0 0 1 1 1 0 Sperm tail bZIP_1 PF00170.16 EDO08726.1 - 0.13 12.1 1.7 0.42 10.6 1.2 1.8 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 EDO08726.1 - 1.5 8.3 5.0 0.48 9.9 1.1 1.9 2 0 0 2 2 2 0 Septum formation initiator GTP_EFTU PF00009.22 EDO08727.1 - 7.4e-48 162.4 0.0 1.1e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EDO08727.1 - 4.5e-34 116.5 0.0 9.4e-34 115.5 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EDO08727.1 - 7.6e-19 67.3 0.0 1.7e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDO08727.1 - 4.7e-06 26.6 0.2 1.5e-05 25.0 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO08727.1 - 6e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 EDO08727.1 - 0.00011 21.9 0.1 0.00077 19.2 0.0 2.4 2 1 0 2 2 2 1 Elongation Factor G, domain II Miro PF08477.8 EDO08727.1 - 0.0014 19.1 0.0 0.0029 18.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EDO08727.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Ras family Porin_3 PF01459.17 EDO08728.1 - 2.9e-26 92.3 0.1 3.9e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin BRAP2 PF07576.7 EDO08728.1 - 0.054 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 Patatin PF01734.17 EDO08730.1 - 2e-09 37.6 0.0 3.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Aconitase PF00330.15 EDO08731.1 - 4.5e-132 440.8 0.0 5.8e-132 440.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDO08731.1 - 8.2e-41 139.1 0.0 1.4e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L2_C PF03947.13 EDO08732.1 - 1.4e-41 141.2 1.3 2.1e-41 140.7 0.9 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EDO08732.1 - 5.3e-16 58.3 0.9 1.1e-15 57.2 0.6 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain RNase_PH PF01138.16 EDO08733.1 - 4.6e-17 62.5 0.0 5.9e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Spc97_Spc98 PF04130.8 EDO08734.1 - 2.1e-08 32.9 0.0 0.00098 17.5 0.0 2.7 2 1 0 2 2 2 2 Spc97 / Spc98 family PSRP-3_Ycf65 PF04839.8 EDO08734.1 - 0.056 13.5 0.2 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) Yos1 PF08571.5 EDO08735.1 - 4.5e-21 74.7 4.2 6.1e-21 74.3 2.9 1.2 1 0 0 1 1 1 1 Yos1-like tRNA-synt_1c PF00749.16 EDO08736.1 - 3.3e-96 321.6 0.0 4.4e-96 321.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EDO08736.1 - 3.6e-37 127.6 0.0 1.3e-36 125.8 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EDO08736.1 - 2.1e-05 24.9 0.1 7e-05 23.2 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDO08736.1 - 0.0016 18.3 0.0 0.005 16.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ub-Mut7C PF14451.1 EDO08736.1 - 0.086 12.3 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Mut7-C ubiquitin HIT PF01230.18 EDO08739.1 - 4.6e-26 91.2 0.2 5.8e-26 90.8 0.2 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EDO08739.1 - 8e-22 77.6 0.1 1.1e-21 77.2 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CDH PF02611.10 EDO08739.1 - 0.065 12.4 0.1 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase CoA_binding_3 PF13727.1 EDO08743.1 - 7.6 6.3 9.1 0.33 10.7 0.7 2.3 2 0 0 2 2 2 0 CoA-binding domain LRR_adjacent PF08191.6 EDO08744.1 - 0.19 11.4 1.1 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 LRR adjacent Band_7 PF01145.20 EDO08745.1 - 0.00054 19.9 0.0 0.72 9.7 0.0 3.6 1 1 2 3 3 3 2 SPFH domain / Band 7 family DUF2014 PF09427.5 EDO08745.1 - 0.015 14.4 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2014) VESA1_N PF12785.2 EDO08746.1 - 4.3e-222 738.0 28.8 4.3e-222 738.0 19.9 2.4 3 0 0 3 3 3 1 Variant erythrocyte surface antigen-1 YtxH PF12732.2 EDO08746.1 - 0.015 15.6 1.4 0.071 13.4 0.0 2.7 2 1 0 2 2 2 0 YtxH-like protein VESA1_N PF12785.2 EDO08747.1 - 1.1e-21 77.4 17.0 1.1e-21 77.4 11.8 4.6 3 1 1 4 4 4 2 Variant erythrocyte surface antigen-1 F-box-like_2 PF13013.1 EDO08748.1 - 5.4e-05 22.8 0.2 0.0014 18.3 0.1 2.2 1 1 1 2 2 2 2 F-box-like domain VESA1_N PF12785.2 EDO08749.1 - 6.9e-10 38.4 9.7 1.1e-09 37.8 6.7 1.3 1 1 0 1 1 1 1 Variant erythrocyte surface antigen-1