GenomeFlowInterface Settings: shuffle: True pos_sampling_rate: 0.05 validation_chroms: ['chr22'] holdout_chroms: ['chr1', 'chr8', 'chr21'] optimizer: adam learning rate: 0.0003 batch size: 256 epoch size: 2500000 max num of epochs: 100 early stopping metrics: auPRC early stopping patience: 4 Epoch 1: Metrics across all datasets: Balanced Accuracy: 91.89% auROC: 0.995 auPRC: 0.321 Recall at 5% | 10% | 25% | 50% FDR: 1.1% | 3.8% | 10.0% | 26.5% Num Positives: 548 Num Negatives: 1024331 New best auPRC. Saving model. Epoch 2: Metrics across all datasets: Balanced Accuracy: 89.78% auROC: 0.990 auPRC: 0.257 Recall at 5% | 10% | 25% | 50% FDR: 0.5% | 0.5% | 1.5% | 18.6% Num Positives: 548 Num Negatives: 1024331 Epoch 3: Metrics across all datasets: Balanced Accuracy: 89.60% auROC: 0.983 auPRC: 0.203 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 0.0% | 14.2% Num Positives: 548 Num Negatives: 1024331 Epoch 4: Metrics across all datasets: Balanced Accuracy: 80.28% auROC: 0.981 auPRC: 0.252 Recall at 5% | 10% | 25% | 50% FDR: 0.5% | 0.5% | 1.1% | 19.9% Num Positives: 548 Num Negatives: 1024331 Epoch 5: Metrics across all datasets: Balanced Accuracy: 84.49% auROC: 0.989 auPRC: 0.236 Recall at 5% | 10% | 25% | 50% FDR: 1.6% | 2.0% | 3.1% | 9.3% Num Positives: 548 Num Negatives: 1024331 Epoch 6: Metrics across all datasets: Balanced Accuracy: 80.79% auROC: 0.987 auPRC: 0.272 Recall at 5% | 10% | 25% | 50% FDR: 2.0% | 3.3% | 6.6% | 21.2% Num Positives: 548 Num Negatives: 1024331 Finished training after 6 epochs. The best model's architecture and weights (from epoch 1) were saved to /users/marinovg/2018-01-25-histone-mods/tfdragonn-SequenceAndDnaseClassifier-K562-ATAC-02-cuts-CTCF-N-ChIP/model.arch.json and /users/marinovg/2018-01-25-histone-mods/tfdragonn-SequenceAndDnaseClassifier-K562-ATAC-02-cuts-CTCF-N-ChIP/model.weights.h5