GenomeFlowInterface Settings: shuffle: True pos_sampling_rate: 0.05 validation_chroms: ['chr22'] holdout_chroms: ['chr1', 'chr8', 'chr21'] optimizer: adam learning rate: 0.0003 batch size: 256 epoch size: 2500000 max num of epochs: 100 early stopping metrics: auPRC early stopping patience: 4 Epoch 1: Metrics across all datasets: Balanced Accuracy: 88.75% auROC: 0.985 auPRC: 0.290 Recall at 5% | 10% | 25% | 50% FDR: 0.6% | 0.6% | 0.9% | 19.2% Num Positives: 1135 Num Negatives: 1022650 New best auPRC. Saving model. Epoch 2: Metrics across all datasets: Balanced Accuracy: 83.18% auROC: 0.967 auPRC: 0.278 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 0.0% | 0.0% Num Positives: 1135 Num Negatives: 1022650 Epoch 3: Metrics across all datasets: Balanced Accuracy: 79.32% auROC: 0.968 auPRC: 0.278 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 0.0% | 0.0% Num Positives: 1135 Num Negatives: 1022650 Epoch 4: Metrics across all datasets: Balanced Accuracy: 79.39% auROC: 0.977 auPRC: 0.254 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 0.0% | 2.5% Num Positives: 1135 Num Negatives: 1022650 Epoch 5: Metrics across all datasets: Balanced Accuracy: 73.37% auROC: 0.958 auPRC: 0.268 Recall at 5% | 10% | 25% | 50% FDR: 0.1% | 0.1% | 0.1% | 16.1% Num Positives: 1135 Num Negatives: 1022650 Epoch 6: Metrics across all datasets: Balanced Accuracy: 77.16% auROC: 0.971 auPRC: 0.260 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 0.0% | 0.0% Num Positives: 1135 Num Negatives: 1022650 Finished training after 6 epochs. The best model's architecture and weights (from epoch 1) were saved to /users/marinovg/2018-01-25-histone-mods/tfdragonn-SequenceAndDnaseClassifier-K562-ATAC-cuts-SP1/model.arch.json and /users/marinovg/2018-01-25-histone-mods/tfdragonn-SequenceAndDnaseClassifier-K562-ATAC-cuts-SP1/model.weights.h5