ó
ƒå˜[c           @` s¾   d  d l  m Z m Z m Z m Z d  d l Z d  d l Z d  d l Z d  d l Z d  d l	 Z	 d  d l
 Z
 d  d l Z d  d l m Z d  d l Z e j e ƒ Z d Z d d d „  ƒ  YZ d S(   i    (   t   absolute_importt   divisiont   print_functiont   unicode_literalsN(   t   Topological_sortgš™™™™™©?t   Compact_graph_wholec           B` sb   e  Z d  „  Z d „  Z d „  Z d „  Z d „  Z d „  Z d „  Z d „  Z	 d „  Z
 d	 „  Z RS(
   c         C` s   d  S(   N(    (   t   self(    (    sƒ   /oak/stanford/groups/akundaje/marinovg/programs/trinityrnaseq-Trinity-v2.8.4/Analysis/SuperTranscripts/pylib/Compact_graph_whole.pyt   __init__   s    c         C` s5  t  j | j ƒ  ƒ } x| D]} | j ƒ  r4 q n  t j d j | j ƒ  ƒ ƒ t | j	 ƒ  ƒ } t
 | ƒ d k r | d } t
 | j ƒ  ƒ d k r» t j d j | | j ƒ  ƒ ƒ q n  t j d j | | ƒ ƒ | j | j ƒ  ƒ | j | j ƒ  | j ƒ  ƒ | j | j	 ƒ  | g ƒ | j | ƒ q q Wd  S(   Nu   compact_unbranched( {} )i   i    u8   prev node: {} id downward branched, so can't compact. {}u$   linear compaction of nodes {} and {}(   R   t   topologically_sortt   get_all_nodest   is_deadt   loggert   debugt   formatt   toStringt   listt   get_prev_nodest   lent   get_next_nodest   add_transcriptst   get_transcriptst   set_seqt   get_seqt	   add_edgest
   prune_node(   R   t   tgrapht	   all_nodest   nodet
   prev_nodest	   prev_node(    (    sƒ   /oak/stanford/groups/akundaje/marinovg/programs/trinityrnaseq-Trinity-v2.8.4/Analysis/SuperTranscripts/pylib/Compact_graph_whole.pyt   compact_unbranched   s     
c   
      C` sÿ  t  } d } xì| rú| d 7} t j d j | | ƒ ƒ | j ƒ  t } t j | j ƒ  ƒ } t	 j
 rž d j | | ƒ } | j | ƒ t j d j | ƒ ƒ n  xÿ | D]÷ } | j ƒ  d k rÃ q¥ n  t j d j | | j ƒ  ƒ ƒ | j ƒ  } t | ƒ d k r?|  j | ƒ r?|  j | | ƒ r?|  j | | ƒ r?t  } q?n  | j ƒ  }	 t |	 ƒ d k r¥ |  j |	 ƒ r¥ |  j | |	 ƒ r¥ |  j |	 | ƒ rœt  } qœq¥ q¥ W| r t	 j
 rçd j | | ƒ } | j | ƒ t j d j | ƒ ƒ n  |  j | ƒ q q Wd  S(   Ni    i   u)   
	### Num allowed variants: {}, Round: {}u8   ladeda.compacted_whole.BEGIN.num_allowed_{}.round_{}.dotu   -wrote dot: {}u5   

///////// R[{}]  Exploring compaction at node: {}

u6   ladeda.compacted_whole.END.num_allowed_{}.round_{}.dot(   t   TrueR   R   R   t   clear_touch_settingst   FalseR   R   R	   t   TGLOBALSt   DEBUGt
   draw_grapht   get_touched_valR   R   R   t	   untouchedt$   all_have_lower_topological_orderingst   compact_upwardR   t%   all_have_higher_topological_orderingst   compact_downwardR   (
   R   R   t   num_allowed_variantst   compacted_flagt   roundt   sorted_nodest   dot_filenameR   R   t
   next_nodes(    (    sƒ   /oak/stanford/groups/akundaje/marinovg/programs/trinityrnaseq-Trinity-v2.8.4/Analysis/SuperTranscripts/pylib/Compact_graph_whole.pyt   compact_graph8   s<    	

	33	c         C` s+   x$ | D] } | j  ƒ  d k r t Sq Wt S(   Ni   (   R%   R!   R   (   R   t	   node_listR   (    (    sƒ   /oak/stanford/groups/akundaje/marinovg/programs/trinityrnaseq-Trinity-v2.8.4/Analysis/SuperTranscripts/pylib/Compact_graph_whole.pyR&   g   s    c         C` sR   | j  ƒ  } | d k  r' t d ƒ ‚ n  x$ | D] } | j  ƒ  | k r. t Sq. Wt S(   Ni    u*   Error, must run topological ordering first(   t   get_topological_ordert   RuntimeErrorR!   R   (   R   R   t   other_nodes_listt
   topo_ordert
   other_node(    (    sƒ   /oak/stanford/groups/akundaje/marinovg/programs/trinityrnaseq-Trinity-v2.8.4/Analysis/SuperTranscripts/pylib/Compact_graph_whole.pyR'   o   s    c         C` sR   | j  ƒ  } | d k  r' t d ƒ ‚ n  x$ | D] } | j  ƒ  | k  r. t Sq. Wt S(   Ni    u*   Error, must run topological ordering first(   R3   R4   R!   R   (   R   R   R5   R6   R7   (    (    sƒ   /oak/stanford/groups/akundaje/marinovg/programs/trinityrnaseq-Trinity-v2.8.4/Analysis/SuperTranscripts/pylib/Compact_graph_whole.pyR)   z   s    c         C` s’   t  j d j | | ƒ ƒ t | ƒ } xf t d t | ƒ d ƒ D]K } xB t | d t | ƒ ƒ D]' } |  j | | | | | ƒ r_ t Sq_ Wq? Wt S(   Nu+   compact_upward: {} max_allowed_variants: {}i    i   (	   R   R   R   R   t   rangeR   t   compact_upward_node_pairR   R!   (   R   R   R+   t   it   j(    (    sƒ   /oak/stanford/groups/akundaje/marinovg/programs/trinityrnaseq-Trinity-v2.8.4/Analysis/SuperTranscripts/pylib/Compact_graph_whole.pyR(   ˆ   s      c         C` s  t  j d j | | | ƒ ƒ | j | ƒ s: | j | ƒ rW t  j d j | | ƒ ƒ t St  j d j | | ƒ ƒ t | j ƒ  ƒ t | j ƒ  ƒ k  r¤ | | } } n  | j ƒ  } | j ƒ  } t | ƒ } | d  d  d … } | d  d  d … } d }	 x8 t d | ƒ D]' }
 | |
 | |
 k r|	 d 7}	 qqW|	 | k r^t  j d j |	 | | | ƒ ƒ t S|	 | t k r”t  j d j |	 | t | | ƒ ƒ t S| j	 ƒ  } t  j d	 j | j
 ƒ  ƒ ƒ t  j d
 j | j
 ƒ  ƒ ƒ | j | j ƒ  ƒ | j | g | j ƒ  ƒ | j | g | j ƒ  ƒ | j ƒ  | j ƒ  t | ƒ | k r†t | ƒ | } | d | !} | j | ƒ | j | g | g ƒ n& | j | j ƒ  | g ƒ | j | ƒ t  j d j | j
 ƒ  ƒ ƒ t  j d j | j
 ƒ  ƒ ƒ t  j d j | | ƒ ƒ t S(   Nu9   compact_upward_node_pair({}, {}, num_allowed_variants: {}u6   -not parallel paths. excluding compaction of {} and {}u   -not ancestral: {}, {}iÿÿÿÿi    i   u.   num_mm: {} exceeds {} for node pair: {} and {}uE   num_mm: {} / len: {} exceeds max mm rate: {} for node pair: {} and {}u   node_A before mods: {}u   node_B before mods: {}u   node_A after mods: {}u   node_B after mods: {}u%   

	*** compacted nodes: {} and {} ***(   R   R   R   t   is_ancestralR!   R   R   R8   t   MAX_MM_RATEt	   get_graphR   R   R   R   R   t   prune_edgest   touchR   R   R   R   (   R   t   node_At   node_BR+   t   seqAt   seqBt   shorter_lent   seqA_revt   seqB_revt   num_mmR:   R   t   delta(    (    sƒ   /oak/stanford/groups/akundaje/marinovg/programs/trinityrnaseq-Trinity-v2.8.4/Analysis/SuperTranscripts/pylib/Compact_graph_whole.pyR9   •   sT    $

c         C` s’   t  j d j | | ƒ ƒ t | ƒ } xf t d t | ƒ d ƒ D]K } xB t | d t | ƒ ƒ D]' } |  j | | | | | ƒ r_ t Sq_ Wq? Wt S(   Nu-   compact_downward: {} max_allowed_variants: {}i    i   (	   R   R   R   R   R8   R   t   compact_downward_node_pairR   R!   (   R   R0   R+   R:   R;   (    (    sƒ   /oak/stanford/groups/akundaje/marinovg/programs/trinityrnaseq-Trinity-v2.8.4/Analysis/SuperTranscripts/pylib/Compact_graph_whole.pyR*   ì   s      c   
      C` s“  | j  | ƒ s | j  | ƒ r; t j d j | | ƒ ƒ t St | j ƒ  ƒ t | j ƒ  ƒ k  ro | | } } n  | j ƒ  } | j ƒ  } t | ƒ } d } x8 t d | ƒ D]' } | | | | k r© | d 7} q© q© W| | k rt j d j | | | | ƒ ƒ t S| | t k r9t j d j | | t | | ƒ ƒ t S| j	 ƒ  }	 t j d j | j
 ƒ  ƒ ƒ t j d j | j
 ƒ  ƒ ƒ | j | j ƒ  ƒ |	 j | j ƒ  | g ƒ |	 j | j ƒ  | g ƒ | j ƒ  | j ƒ  t | ƒ | k r| | } | j | ƒ |	 j | g | g ƒ n& |	 j | g | j ƒ  ƒ |	 j | ƒ t j d j | j
 ƒ  ƒ ƒ t j d	 j | j
 ƒ  ƒ ƒ t j d
 j | | ƒ ƒ t S(   Nu6   -not parallel paths. excluding compaction of {} and {}i    i   u.   num_mm: {} exceeds {} for node pair: {} and {}uE   num_mm: {} / len: {} exceeds max mm rate: {} for node pair: {} and {}u   node_A before mods: {}u   node_B before mods: {}u   node_A after mods: {}u   node_B after mods: {}u%   

	*** compacted nodes: {} and {} ***(   t   is_descendantR   R   R   R!   R   R   R8   R=   R>   R   R   R   R   R   R?   R@   R   R   R   R   (
   R   RA   RB   R+   RC   RD   RE   RH   R:   R   (    (    sƒ   /oak/stanford/groups/akundaje/marinovg/programs/trinityrnaseq-Trinity-v2.8.4/Analysis/SuperTranscripts/pylib/Compact_graph_whole.pyRJ   ø   sJ    $


(   t   __name__t
   __module__R   R   R1   R&   R'   R)   R(   R9   R*   RJ   (    (    (    sƒ   /oak/stanford/groups/akundaje/marinovg/programs/trinityrnaseq-Trinity-v2.8.4/Analysis/SuperTranscripts/pylib/Compact_graph_whole.pyR      s   			/					W	(    (   t
   __future__R    R   R   R   t   ost   syst   ret   loggingt   TGrapht   TNodet   Node_alignmentR   R"   t	   getLoggerRL   R   R=   R   (    (    (    sƒ   /oak/stanford/groups/akundaje/marinovg/programs/trinityrnaseq-Trinity-v2.8.4/Analysis/SuperTranscripts/pylib/Compact_graph_whole.pyt   <module>   s   "$