# FREQS A 0.275 C 0.225 G 0.225 T 0.275
    A   R   G   C   Y   T   K   M   S   W   N   X
A   9   2  -4 -15 -16 -17 -10  -2  -9  -3  -1 -30
R   0   1   2 -15 -15 -16  -6  -7  -6  -7  -1 -30
G  -8   1  10 -15 -15 -14  -2 -11  -2 -11  -1 -30
C -14 -15 -15  10   1  -8 -11  -2  -2 -11  -1 -30
Y -16 -15 -15   2   1   0  -7  -6  -6  -7  -1 -30
T -17 -16 -15  -4   2   9  -2 -10  -9  -3  -1 -30
K -12  -7  -2  -9  -6  -2  -2 -11  -6  -7  -1 -30
M  -2  -6  -9  -2  -7 -12 -11  -2  -6  -7  -1 -30
S -11  -7  -2  -2  -7 -11  -7  -7  -2 -11  -1 -30
W  -3  -6  -9  -9  -6  -3  -6  -6  -9  -3  -1 -30
N  -1  -1  -1  -1  -1  -1  -1  -1  -1  -1  -1 -30
X -30 -30 -30 -30 -30 -30 -30 -30 -30 -30 -30 -30