# FREQS A 0.305 C 0.195 G 0.195 T 0.305
    A   R   G   C   Y   T   K   M   S   W   N   X
A   8   2  -4 -14 -16 -17 -11  -2  -9  -4  -1 -30
R   0   1   3 -14 -15 -16  -6  -7  -5  -8  -1 -30
G  -8   1  10 -14 -14 -15  -2 -11  -1 -11  -1 -30
C -15 -14 -14  10   1  -8 -11  -2  -1 -11  -1 -30
Y -16 -15 -14   3   1   0  -7  -6  -5  -8  -1 -30
T -17 -16 -14  -4   2   8  -2 -11  -9  -4  -1 -30
K -13  -7  -1  -9  -6  -3  -2 -11  -5  -8  -1 -30
M  -3  -6  -9  -1  -7 -13 -11  -2  -5  -8  -1 -30
S -11  -6  -1  -1  -6 -11  -6  -6  -1 -11  -1 -30
W  -4  -6  -9  -9  -6  -4  -6  -6  -9  -4  -1 -30
N  -1  -1  -1  -1  -1  -1  -1  -1  -1  -1  -1 -30
X -30 -30 -30 -30 -30 -30 -30 -30 -30 -30 -30 -30