OMA StandAlone Version 0.99z.2 ---------------------------------- Installation ------------ To install this software on your system, run the included installer script: ./install.sh [install_prefix] If you do not choose an install prefix, OMA will be installed in /usr/local/OMA (for that, you might need to install it using the root account or sudo). After installation, make sure the bin folder of OMA is in your PATH variable, e.g., if you are using bash, add a line in ~/.profile such as: export PATH=$PATH:/usr/local/OMA/bin For other shells, choose the appropriate syntax. Usage ----- First, set up a working directory. Copy the file 'parameters.drw' into this folder and change it to your needs. Create a directory 'DB' in your working directory that holds the genome data in fasta format (filename ending with .fa)and copy your data into this directory. If you want to use ESPRIT, the fasta file should be called {YourGenome}.contig.fa . Then, simply call oma from your working directory to run OMA and/or ESPRIT. If you have not installed OMA yet, use the complete path to 'bin/oma' in the installer folder to start OMA. To get a first impression of OMA, you could cd into the 'ToyExample' directory, have a look at 'parameters.drw' and run 'oma' to process our example files. For more information about OMA and ESPRIT, please have a look at http://omabrowser.org/Algorithm.html . OMA/ESPRIT is built on top of Darwin, a bioinformatics software package created by CBRG at ETHZ. For more information about Darwin itself, have a look at http://www.cbrg.ethz.ch/darwin/index or [Gonnet, 2000, 'Darwin v.2.0: An interpreted computer language for the biosciences', Bioinformatics Vol. 16/2]. License ------- OMA standalone is licensed under a Mozilla Public License Version 2.0. For more info, please consult the following page: http://www.mozilla.org/MPL/2.0/ In a nutshell, OMA standalone is open source and free for commercial and non-commercial use. Software distributed under the License is distributed on an "AS IS" basis, WITHOUT WARRANTY OF ANY KIND, either express or implied. See the License for the specific language governing rights and limitations under the License.